PharMolix/UniProtQA huggingface dataset:
Protein: SYK_NEIG2
Sequence: MSEQNHPQTEPQLDENQIIALRREKLNNIRQQRNAYPNDFKRDSFAADLQAQYGEIGKEELDPQAVPVKIAGRMMLKRQMGKASFATIQDVTGQIQLYLNNKGVSQEVLDGFNHWDLGDIVGAEGTLFKTNHGELTVRVSDIRLLSKSLRPLPDKHKGLSDQETKYRQRYVDLIANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMMHPIPGGATAKPFVTHHNALDIPLYLRIAPELYLKRLVVGGLERVFEINRSFRNEGMSVRHNPEFTMIEFYEAFSDYERMMQMAEDIIRNASRTVNGTANITYNGKEVDLESPFERLTILEAIKKYNPHYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDYPVEVSPLARASDTKQGLTERFELFVVGRELANGYSELNDPEDQAERFKSQVAQKDAGDDEAMHYDADYIRAMEFGLPPTGGCGIGIDRLVMLLTDLQTIRDVILFPQMRPE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_RICCN
Sequence: MSSLIKEIEEAWQIKDKLLQDSSKLITLKQTLNDIIESLNQGTIRVCEKQENSWHVNEWVKKAILLYFITTESQLYNNNYNSWYDKVAPKFSADTDKNTFKEAAIRKVPGAVVRTGTYIAKNVVIMPSFINIGAYIDEGTMIDTWATIGSCAQIGKNCHISGGTGIGGVLEPLQAKPVIIEDNCFIGARSEIAEGVIVEEGAVISMGVFIGSSTKIVYRDTGEIIYGRIPAYSVVVPGVLPAKEAGKPGLYCVVIVKQVDKTTRAKVSINDLLR
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_EHRCJ
Sequence: MSDSKNLNQERQKALDNAISQIEKAFGRGAIMKLKQGAIEKIDSISTGSIALDTALGIGGFPKGRIVEIFGPESSGKTTLALHVIAESQKKGGNCAFIDAEHALDIMYARKLGVNTGDLIVSQPDTGEQALHIVEYLVCSGAIDVIVVDSVAALTPRAEIEGDMGDQHMGLQARLLSHALRKLTSIVSKANCVLIFINQIRMKIGVVYGNPETTTGGNALKFYSSVRLDIRKVSAIKDKDLIIGNQTKVKVVKNKVAPPFKQVDFDIMYNEGISKVGEIIDMGVKLNIIEKAGAYYSYNGIRLGQGKENAKSYLKTNYTTADEIEQKIRNMLASDSDVTCFNTEGSDNLHEVEEAIF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_HELP2
Sequence: MDIKACYQNAQALLEGHFLLSSGFHSNYYLQSAKVLEDPKLAEQLAKELAKQIQEAHLNIECVCSPAIGGILAGYELARALGVRFIFTERVDNTMTLRRGFEVKKNEKILVCEDIITTGKSAMECTKVLEEKGAQIVAFGALANRGICKRTHSHLKAQEGACLPSHLPLFALEDFVFDMHKPNSCPLCATSVAIKPGSRGN
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RNY1A_CANAL
Sequence: MLSILSIAALLIATVQAADFSSSCPIDSPISCSSNGDTSNSCCYENPGGIILFTQFWDYNPASGPADSFTIHSIWNDYCSGGYPQFCDTSLEIDSTGSTIESIVVDQFGDQTLYDNMNKYWTDINGNNKKFWAHEFNKHGTCLNTLNPSCYSNYKQNENVYDYYSLVYQLFQKLPTYQWLVSAGIKPSTTATYTLSQIQSALKSKFGAEVYIACDSNNAINEVWYFYNIKGSILQQNYLPIDTVSKTNCPSSGIKFPPKGNSGANTLTTKTTGTTTSGSGSTSVPATSYINLTGKSGCLISNGKYYTSGTCATYHFNAGSSGNTQITSSKGNCGIDSSNQFTCSSSTSATDFQVSGGSIGYNGNFDWCLGAVTGSGSTAQTSVKLSDGSCSSFKLTLSS
What is the function of this protein?
Rnase which modulates cell survival under stress conditions.  Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death.  Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration (By similarity).
What are the official names of this protein?
Ribonuclease T2-like 1-A, RNase T2-like A.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Vacuole lumen. Cytoplasm. Note=Is released from the vacuole to the cytoplasm during stress conditions like oxidative stress or stationary phase stress.
Protein: RTC1_CANGA
Sequence: MNFSPNKNMPAGSGGNGQDRVLHRTSSSAGKNAMKGVFSQPHLSGANSSTHMYIHDSAVRPKLTAKYSYGSTYAVGSQWYDFSSSNRGPSNSYGSSYEDKFIMGNANRRRTGTPYQGNQFHGTHNHAHSHSQYSSSPHISSSRSKSSQKSDAKKSTIKFHHRTNNEISSIDKVNDPSMQGLICAGKTHLGYYKFSTVDNSMTCVHDFITSNNRNTPKGNSWILPNLSKRTKGAKISNIADVKCGFHNYSNVIAICNNSTDISLYDLNRTTPAEDPMIQILSGHTRAINSFDFNMSQTNLIISGGQDGCVKVWDIRSDSMKRQGRSDLNIKTANDSIRDVKWMPSHNFASLPSSADGKSLNISSPGYTFASIHDTGVLLKYDLRQTTQVDKKINAHSGPGLCLNWHPHQDYIATGGRDGKCSLWYVGDRRSTDQSPYSTTFLSSNATTNTSSIGIGYPGNPVASTFIPETTINTGSPITKLKFRPNYDKIALNSLIALSSMGDEAEVNIYSLARKYIPKHLLTTGKPSLGLVWWNSNLIFNVDSAGYINGWDITNEPTVLDELPKNIVRWRDVDGSGLLFLNQDTGSYEVSDQDELIDLHTFQKQSSSTVKGDTATPGIGLMANIKRGLSHNNVSHFPTERPIPKRSAFSNISKVPISSSTQSSVNKSSTSLSTLATQDELLENKFLKSPLVIPFELPEAYQYSRESKIMELNKRSYIPKVSSVRGSNIEVFKFLARELEFSFRQDKNNEDDAELSRQQSVNEENIRSDLMKRFDISENATWANIVKDKSNKTRERANSISIKQSPIVLSDESEIKSPTIQKLESGDNNVKYESNITKEIQQEKTKNFNPEYRINLLLELVESSNHNASVYSIIDDLPNFKIWMLIRDSLLWDIKMYSSFSENETPEELTGGQLEYPLTNTRKQSLVSDLSRLGTSELSSDYAEHPHAYHGKSDYSSDASEGIKSPVSKLGEQLKGEESNKFVLGRRLSSMSPKRSPDIPKLAAALKIHRQRNENNRESEIESSAIEEEEEDEEEDDDKFNDDEDFKGPATTKDNTIHSIPILNKREARTSFIDTFMTNENSPDAFHNVPYLNKNQSPGYGYSSPKNKNGPSHSFANTPSKLAFLKKLSPRTMSSHSVTRAPSSDWHVEHDPTLQVPPPEKKGAPDNLPPWNTTKLLRQIHANALEMGNVILAVNVLILFQDVYNIAPISIVKESVVHFVRLLHQYELFEIAAAILKYCPWDDLLGPEGDQSTVEIFCERCGELITNEQGKDLPHGYWYCQACSRTNTLCVVCNTPLRKLTMAALKCGHEGHFECFTQWFITEGMSECPAGCTAALL
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RTC1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: NUOC_CERS4
Sequence: MPEALQELAAHVRMRQPDAILGHRVEFGELTLDVVPNRIVGLVEFLRSDASCRFSSLVDITAIDHPERPARFDVVYHFLSMYQNQRIRLKMQVREDETVASIHSVHPSANWFEREVFDMFGILFTGHPDLRRILTDYGFRGHPMRKDFPTTGYTEVRYDEVQKRVVYEPVKLVQEYRQFDFLSPWEGADYILPGDDKART
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: XYNC_PHACH
Sequence: MFKFSASLAALAALVPFVAAQSPEWGQCGGIGWTGPTTCVAGTTCVESNPYYSQCLPGAASVAPPPPSGTSSAGGSTPSSSAKLHTLAKAAGKLYFGTATDNNELTDTAYTAILDDNTMFGQITPANSMKWDATEPQQGVFTFSGGDQIATLAKTNGMLLRGHNCVWYNQLPSWVSSGSFTAAQLTSIIQNHCSTLVTHYKGQVYAWDVVNEPFNDDGTWRTDVFYNTLGTSYVQIALEAARAADPNAKLYINEYNIEFAGAKATSLLNLVKSLKAADVPLDGIGFQCHLIVGEFSGPGLQTQLSTFAAQGVEVAITELDIRMTLPSTPALLAQQQTDYNSVITACMNVESCIGVTVWDWTDKYSWVPNTFSGQGAACPWDQNFVKKPAFNGIAAGFSA
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase C, Xylanase C, 1,4-beta-D-xylan xylanohydrolase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: METE_STAAC
Sequence: MTTIKTSNLGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDLHKENLLLQKYYHLDSIPVGDFSLYDHILDTSLLFNIIPERFQGRTIDDDLLFDIARGNKDHVASALIKWFNTNYHYIVPEWDNVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPITFVKLSKGGHQTFEEKVKTLLPLYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITREAYDYFEKAGVAKKLVIQTYFERAHLKFLSSLPVGGIGLDFVHDNGYNLKQIEAGDFDKSKTLYAGIIDGRNVWASDIEAKKVLIDKLLAHTNELVIQPSSSLLHVPVSLDDETLDTSVGEGLSFATEKLDELDALRRLFNQNDSVKYDKLKARYERFQNQSFKNLDYDFESVRTSRQSPFAQRIEQQQKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFLKNEIARWIKIQEDIGLDVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPIIYGDVKWTAPLTVDETVYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQIALAINEEVLALEAAGIKVIQVDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDETQIHTHMCYSQFGQIIHAIHDLDADVISIETSRSHGDLIKDFEDINYDLGIGLGVYDIHSPRIPTKEEITTAINRSLQQIDRSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKRQE
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: GATA_CAMHC
Sequence: MITLKEALKLSKDEILALRKELKDKILKTKDLGAYIEQLTGEDLNESGSGIPIAIKDNIQVKNWSVTSASNILQGYVAPYDATVITKLRSAGFAPFGRTNMDEFAMGSTTESSFYGKTLNPTDYSRVPGGSSGGSAAAVAAGIAVAALGSDTGGSIRQPAAFCGCVGFKPTYGRVSRYGLAAYSSSLDQIGPITQNVTDAAILFDVIAGYDKMDSTSYSKEFISTADKLNSDRKLTIAVIENFVNETKDEVKSALLKTIEKLKSAGHKIIYKNLLNSKYNIAAYYIIATAEASTNLSRYDGVRYGNRAKASNLNELYANTRSAGFGEEVQRRMLLGTFVLSSGYYDAYYIKAQKARAYIKKEYEKILDEADLIFMPIAPSVAYKFGELANPLDAYLSDVYTIGVNLAGLPAISVPIAKNSENLNISAQLIGRAYDEQTVLDGALNLEKIIKG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: GSA_GLAP5
Sequence: MTTSQSLFEKAQRVIPGGVNSPVRAFKGVGGTPVFIDSAKGAYITDSEGKRYIDYVGSWGPMVLGHNHPAIIDAVLKAVPNGLSFGAPTAIEIELAELVCKLVPSIEMVRMVSSGTEATMSAIRLARGYTKRDKIIKFEGCYHGHSDSLLVKAGSGALTLGQPSSPGVPEDFAKHTLTCEYNNLASVKQAFEQYPNDIACLIIEPVAGNMNCIPPKEGFLQGLRELCTQYGAVFIIDEVMTGFRVALGGAQSYYGVTPDLTTLGKIIGGGMPVGAFGGKKEIMEFIAPTGPVYQAGTLSGNPIAMSAGLACLTELSKAGNEQLLAEKTKTLAEGFKALADKHGIPMTVQYVGGMFGLFFTEQTKIESYQDVMKCDVKAFNTFFHKMLEKGVYLAPSAFEAGFMSLAHSDEDIAYTLEMADLALAEMK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_HISS2
Sequence: MKFIIKLFPEIMIKSESVRKRFVKILTGNIRNVLNKYDDTVAVVKHWDYIEVRSKNIENRTLLVELLGRIPGIHHFLEVEEKPFVTLHDIFEQTLSDVATQIENKTFCVRVKRKGKHDFSSLDAERYIGGGLNQAVASAKVQLSKPDVTVRIDIENDKMMLIKARHQGIGGYPIGTQEDVLSLISGGFDSGVSSYMLIRRGSRVHYCFFNLGGATHEIGVKQMAYHIWKRFSGSHKVRFVAINFEQVVAEILEKVDNGQMGVVLKRMMVRAASKVAQRFGIQAIVTGEALGQVSSQTLTNLRLIDEVAESLVLRPLITHDKEQIIAKAKEIGTEDIAKSMPEFCGAISKSPTVKAVKEKIEQEESYFDFSVLESAVQNAQYLDIRQIAEQTKKEVSEVDEITVLSANEVILDIRSPEEVDDKPLEISGQNIILMPFYKLSSHFAELDQSKNYVLYCERGVMSKLQALYLREKGFDNVKVLNKIS
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWR1_CRYNJ
Sequence: MSEHNQDLRFLISDDVLNEDPMSTGRFAEEDRGSSDTEQLTDNKNDGEEPKETAVQAAFDGSDDVNRLEEPHNPVSSTANIGNFALLESSSAEVSDASCPATMPILVRQSPKTCSQPRTRKVKLSTLSLSSDPDPDINDPEFKARLEDSNQDDQDEELDLEMEEADSAGRESGEGNRDSEDEGLLADADLPIEVLLRRYGYPVPEGEGAVNGEPEQSESKGREQAAPTSTVSETLPSTKLSLAQPANQTDQSLTDTALPEPRVPEQLIISGKRQRRKKEIWTPDDSEPQHLVGKKRIKKVEIVEKVEADVHQNGDGLVIVEEETMGDEDNDDSKVGQEEEDGHEYDSEEEYDEDEDEEEEGAKEDNVDWDDRQDKEGDIGPRVRQPFLLRGTLRPYQQAGLEWLASLWSNNMNGILADEMGLGKTIQTIALLGHLACDKGVWGQHLIIVPTSVILNWEMEFKKFLPGMKVLTYYGNQKERKEKRVGWHTENTWQVCITSYQIVLADQHIFRRKNWCYMILDEAHNIKNFRSQRWQTLLGFKAQRRLLLTGTPLQNNLMELWSLLYFLMPGGIGADATAVVGFANHKEFMEWFSNPMDKAIETGDAMDEETLETVAKLHTLLRPFILRRLKSEVETQLPGKFEHVVYCRLSKRQRFLYDEFMSRASTHEALTTGGYLGVMNTLMQLRKVCNHPDLFEMRPVKTSFAMDNVARDFEPSDILIRKRLLAEEDERRIDALAIGFGVAHNEAMSGWVARARQTYDASDKLPYAASPLRRGKLSAPPPKDTRSVELWLKYRVWAEEEFSKRRWESIRATNRQRCGISPIYGSTFLSLLGNLPNFLLPQDVQSRREETFADFTPPAAKFITSLPERAKSLEDVIDRFAVIPPNAVARNLATYALPGLEPISHPALTDPAFDTLHRSSVKLQIAFPDASLLQYDCGKLQKLFEMLRDLKSEGHRVLIFTQMTRVLDILEMFLSHNGHRYLRLDGSTKIEDRQVLTERFNSDSRIFVFIASSRSGGVGINLTGADTVFFYDSDWNPSMDRQCMDRAHRIGQTREVHIYRFVSSHTVEENMLRKAEQKRLLDKMVIQEGGFNNDWWGRVGWKDMFGDVPGITDVSGVVEKSGEGIIDIQVEGTPVAEDVEVTRPRAGEERELARALAEVEDEEDAQAARMAQGEGELDLQEFEEGPKAVAKRVRVFEPENSGTPVTTEAGETGDVVEEYDDEPGSVEEYMLKWVEEDWDYFSPYRA
What is the function of this protein?
Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.
What are the official names of this protein?
Helicase SWR1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_EUNNO
Sequence: MPHQQILMLFGLLPVATNISTWWNFGSMLIACSTLQVLTGFFLAVHYTANINLAFSSIIHITRDVPYGWLMQNLHAIGASMFFICIYIHIARGLYYGSYLNKETWLSGTTLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTMTTWLWGGFAINDPTLTRFFALHFILPFGIISMSSLHVMLLHEEGSSNPLGTNSDIDKIPFHPYHTYKDLLMLAAMTTLLLLIVSFSPDIFNDPDNFSKANPLVTPQRIKPEWYFLFAYGILRSIPNKLGGALALTMSIVILLTVPFTHTSKMRSMMFRPFMQMTFWLFAATFMVITWTATKPVEPPFTLIGQAASMIYFLFFISNPIMGWLENKIMKM
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DUSC_ECO57
Sequence: MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVKVFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKTVNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQAGATELVVHGRTKEQGYRAEHIDWQAIGEIRQRLNIPVIANGEIWDWQSAQECMAISGCDSVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQSDTGLYHVARIKQWLSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDIGKLR
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U16 in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(16) synthase, U16-specific dihydrouridine synthase, U16-specific Dus, tRNA-dihydrouridine synthase C.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusC subfamily.
Protein: NRDR_DESHY
Sequence: MHCPFCGNDETKVLESRQVEEGTAVRRRRECERCARRFTTFEKFEDTPLIVVKKDGRREEFSRGKLKAGILRACEKRPVSIEQIETLVYEIEKGLRNGSEREVQSKAIGEAVMNALVHLDEVAYIRFASVYREFKDVQRFLEELHELVEKKSSR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: VA726_ARATH
Sequence: MGQQSLIYSFVARGTVILAEYTEFKGNFTSVAAQCLQKLPSSNNKFTYNCDGHTFNYLADNGFTYCVVVIESAGRQIPMAFLERVKEDFNKRYGGGKASTAKANSLNKEFGSKLKEHMQYCADHPEEISKLSKVKAQVTEVKGVMMENIEKVLDRGEKIELLVDKTENLRSQAQDFRTQGTKMKRKLWFENMKIKLIVFGIIVALILIIILSVCHGFKCT
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
What are the official names of this protein?
Putative vesicle-associated membrane protein 726, AtVAMP726.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type IV membrane protein. Early endosome membrane; Single-pass type IV membrane protein.
Protein: UREF_PSEA7
Sequence: MNSIWARLRLASSQLPIGGYSYSQGLEAALDNGWVRDAESARTWLVDQLQLNLARFEAPLLAGLLRAALAGDWAACDAASERHRASRETRELAQESRQMGFSLQQLLEALPELDDAGRAWLARQDPPNLAAAWAMAARAWRLDAEEALSAWFWNWLENQLAVLMKTLPLGQLAAQKLASSLLPDLDRACAEALRRPAVEGSAAFGLALASMTHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLC5_CAEEL
Sequence: MLVFQTKLQKYQLATLISSVISNFLIFFATITPAWQVADDLDADRYVQSGLWLYCPGQAQCWYIFSDSLINYYEKVDVCRFFLIGDCRKKLLRTPYFFGWHYAVLILNVISMICMSLCAAAVIFSYVKPARSRISVIMLDVFAGFASLLLCVSLIVFMVNAEMLESKYLIGIKNTYEKEYGYSYYLAGLAFVISVITVLFAALVSTYTFLFPEEVADSEYTLKMSNNQFAVRYNNDLPQPYQPPMSQLSMQIPSTEHGSYIAGAISPRGDFKSQTRHFYSY
What are the official names of this protein?
Clc-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the Clc family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VPS8_HUMAN
Sequence: MENEPDHENVEQSLCAKTSEEELNKSFNLEASLSKFSYIDMDKELEFKNDLIDDKEFDIPQVDTPPTLESILNETDDEDESFILEDPTLLNIDTIDSHSYDTSSVASSDSGDRTNLKRKKKLPDSFSLHGSVMRHSLLKGISAQIVSAADKVDAGLPTAIAVSSLIAVGTSHGLALIFGKDQNQALRLCLGSTSVGGQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDPTLAICNDSGGSVFELTFKRVMGVRTCESRCLFSGSKGEVCCIEPLHSKPELKDHPITQFSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAWHFVAVQNYVNPMLAFCRGDVVHFLLVKRDESGAIHVTKQKHLHLYYDLINFTWINSRTVVLLDSVEKLHVIDRQTQEELETVEISEVQLVYNSSHFKSLATGGNVSQALALVGEKACYQSISSYGGQIFYLGTKSVYVMMLRSWRERVDHLLKQDCLTEALALAWSFHEGKAKAVVGLSGDASKRKAIVADRMVEILFHYADRALKKCPDQGKIQVMEQHFQDMVPVIVDYCLLLQRKDLLFSQMYDKLSENSVAKGVFLECLEPYILSDKLVGITPQVMKDLIVHFQDKKLMENVEALIVHMDITSLDIQQVVLMCWENRLYDAMIYVYNRGMNEFISPMEKLFRVIAPPLNAGKTLTDEQVVMGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQVFEFLIRLHSAEASPEEEIYPYIRTLLHFDTREFLNVLALTFEDFKNDKQAVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLARQLAKPDNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIRMAEKAEFYQICEFMYEREHQYDKIIDCYLRDPLREEEVFNYIHNILSIPGHSAEEKQSVWQKAMDHIEELVSLKPCKAAELVATHFSGHIETVIKKLQNQVLLFKFLRSLLDPREGIHVNQELLQISPCITEQFIELLCQFNPTQVIETLQVLECYRLEETIQITQKYQLHEVTAYLLEKKGDIHGAFLIMLERLQSKLQEVTHQGENTKEDPSLKDVEDTMVETIALCQRNSHNLNQQQREALWFPLLEAMMAPQKLSSSAIPHLHSEALKSLTMQVLNSMAAFIALPSILQRILQDPVYGKGKLGEIQGLILGMLDTFNYEQTLLETTTSLLNQDLHWSLCNLRASVTRGLNPKQDYCSICLQQYKRRQEMADEIIVFSCGHLYHSFCLQNKECTVEFEGQTRWTCYKCSSSNKVGKLSENSSEIKKGRITPSQVKMSPSYHQSKGDPTAKKGTSEPVLDPQQIQAFDQLCRLYRGSSRLALLTELSQNRSSESYRPFSGSQSAPAFNSIFQNENFQLQLIPPPVTED
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway.  Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.  The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290).  Functions predominantly in APPL1-containing endosomes (PubMed:25266290).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 8 homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS8 family.
Protein: RL25_AERS4
Sequence: MSFVFQAEVRSDLGKGASRRLRHADQVPAIIYGAGKEAQSITVDHKKFIIAQEKPEFYESVLTLVINGEEVNVKVKAIQRHPVKPKLVHLDFVRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: RL32_HERAR
Sequence: MAVQQNKKTPSKRGMHRSHDFLVAPQLSVEQTTGETHMRHHISPNGFYRGRKVLKTKNDE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: LEUC_KORVE
Sequence: MSGPRTLFEKIWSTHVVCVPDDQPPILYIDRHYVHEVTSPQAFDGLRAAGRKVRRTDLTFATVDHNVPTTSPRLVIKDDVAARQIDALRTNCAAFGVPLFDLTSEEQGIVHVIGPELGLTLPGMTIVCGDSHTSTHGAFGAFAFGIGTSEVEHVLATQCLPQRKPKTMKIEVSGTLPEGVTAKDLALGIIGKLGTDGATGHVIEYCGTAIRALSMEARMTLCNMSIEGGARAGLIGPDEITFAYIRNRQYAPKGAEWDTGVAEWAALNTDEGAKFDREIHINAADLQPQVTWGTNPGMVVSVGANVPDPKATSDDAQRQSYERALTYMDLKPGTPVAQIAVDRVFIGSCTNSRIEDLRAAAKVVSGYHVAATVHAMVVPGSQRIKAKAEEEGLDRVFRDAGFEWRESGCSMCLGMNPDILSPGQRCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAITGHFTDIREWEYK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CCSA_CALFG
Sequence: MIFSTLEHILTHISFSIISIVITIHLLNLLVHDTVGLCDSSEKGMMATFFCITGLLVTRWIYSRHFPLSDLYESLMFLSWSFSIIHMVPYFRNHKNSLSAITAPSAIFTQGFATSGLLTEMHQSAILVPALQSQWLMMHVSMMLLGYASLLCGSLLSVALLVITFRKTLGIPGKNNHFLIGSFPFGEIRYFNEKRKRSVLKKTSFFSFRNYHRYQLTQRLDHCSYRIISLGFTFSTIGILSGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHTRTNQRFQDVGPAIVASMGFLIIWICYFGVNLLGIGLHSYGSFALTSN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.