PharMolix/UniProtQA huggingface dataset:
Protein: LRC18_HUMAN
Sequence: MVKGEKGPKGKKITLKVARNCIKITFDGKKRLDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVPTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPFPKPGESEIFIDSIRRLENLYVVEEKDLCAACLRKCQNARDNLNRIKNMATTTPRKTIFPNLISPNSMAKDSWEDWRIRLTSS
What is the function of this protein?
May be involved in the regulation of spermatogenesis and sperm maturation.
What are the official names of this protein?
Leucine-rich repeat-containing protein 18.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_ECO5E
Sequence: MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HOG1_COCMI
Sequence: MAEFVRAQIFGTTFEITSRYTDLQLVGMGAFGLVCSAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQSLPKRERQPLANKFKNAEPDAVDLLENMLVFDPRKRVRAEQALAHAYLAPYHDPTDEPVADEKFDWSFNDADLPVDTWKIMMYSEILDYHNVDAAVQEQENGS
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase HOG1, MAP kinase HOG1, Mitogen-activated protein kinase SRM1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLCTK_BOVIN
Sequence: MAAALQVLRHLARAPSGPLLWGGPLARMASSMALAEQARQLFESTVGAVLPGPLLQRALSLDPDSGELKVRDRSFQLRQNLYLVGFGKAVLGMAAAAEELLGQHLVQGVISVPKGIRAAMEHAGKQEMLLKPHSRIQVFEGAEDNLPDRDALRAALAIRQLAEGLTADDLLLVLISGGGSALLPAPIPPVTLEEKQTLTKLLAARGATIQELNTIRKALSQLKGGGLAQAAYPAQVVSLILSDVVGDPVEVIASGPTVASIHSVQDCLYILNRYGLRTALPRSVKTVLARADSDPHGPHTCGHVLNVILGSNALALAEAQKQAEALGYRAVVLSTAIQGDVKSVAQFYGLLARVAGAHLALPGAGASVQEDERLYELAADLQLPDLQLKEALEAVVGAPGPVCLLAGGEPTVRLQGSGKGGRNQELALRVGVELGQWPLGTVDVLFLSGGTDGQDGPTEAAGAWVRPELTSQAAAEGLDVATFLAHNDSHTFFCRFQGGAHLLHTGLTGTNVTDAHFLFLHPQ
What are the official names of this protein?
Glycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the glycerate kinase type-2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y007_STRPN
Sequence: MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVNDQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV
What are the official names of this protein?
Uncharacterized protein SP_0007.
Protein: TRPB_STRT1
Sequence: MTYQQPDAKGFYGKFGGQFVPETLMTAVIELDKAYREAKEDSSFQAELDDLLKNYVGRETPLYHAKRLTDYIGGAQIYLKREDLNHTGAHKINNALGQVLLAKRMGKKKIIAETGAGQHGVATATAAALFDMDCTIYMGEEDVKRQALNVFRMELLGAKVFSVTDGSRVLKDAVNAALRAWVAGIEDTHYIMGSALGPAPFPEIVRDFQSVIGREAKRQYAEISGGKLPDAVMACIGGGSNAIGMFYPFVNDKSVAMYGAEASGLGLDTEKHAATFAKGRPGILHGALMDVLQDAHGQIMEAFSISAGLDYPGVGPEHCYFNEIGRATYDSITDEEALEGFKLLSCLEGIIPALESSHAIALAQKVAAKMSPDQSLIVCLSGRGDKDVMQVKERFEAEAEGK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: EAST_DROME
Sequence: MLKPSIICLFLGILAKSSAGQFYFPNEAAQVPNYGRCITPNRERALCIHLEDCKYLYGLLTTTPLRDTDRLYLSRSQCGYTNGKVLICCPDRYRESSSETTPPPKPNVTSNSLLPLPGQCGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQLSASNLKLKAAVEGSRMDECQNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTIES
What is the function of this protein?
Component of the extracellular signaling pathway that establishes the dorsal-ventral pathway of the embryo (PubMed:9477324, PubMed:2107028, PubMed:12493753).  Three proteases; ndl, gd and snk process easter to create active easter (PubMed:9477324).  Active easter defines cell identities along the dorsal-ventral continuum by activating the spz ligand for the Tl receptor in the ventral region of the embryo (PubMed:9477324).
What are the official names of this protein?
Serine protease easter.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPPH_NITSB
Sequence: MEKKRYRPNVAAIVLSSNYPKKVEFFIAARSDVPDSWQFPQGGIDKGESPKEALLRELKEEIGTDKIEIIAEFPEWVSYDFPKKIAKKMYPYDGQTQKYFLVKLKPEAKIDLDTKEPEFNDYKFVPYKDLFHYVTFFKRPVYKKVLEYFKKEGYF
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RLMD_RALPJ
Sequence: MPVAGPLDIVSLDGEARGIGRLTNEDGTPGKVVFVEGALPGERVMYRSHRVKPSYEQAGVVNILRQSASRVTPQCKFFGVCGGCSMQHLDSRAQVAIKQRVLEDDLWHLAKLRPDVVFRPIAGPDWGYRYRARLTVRHVAAKGGVLVGFHERKSSYVADMTSCEVLPPHVSALLVPLRELVGRLSIVQRMPQIELAVGQDVTALVLRNLEPITAEDEAELRAFADHHNIQFWLQPKGPDTVYPFYPLDRTLTYTLPEFGITMPFKPTDFTQVNHQINRVLMSRALKLLDAQPGDRLLDLFCGIGNFTLPMATRAREVMGIEGSEALTTRALANAQHNGLHTKTSFACRNLFEVSADDVAALGKFDRWLIDPPREGALAVSKALAELSQSGGDAADLLPKRIIYVSCNPATLARDAGLLVHEAGYRLAGAGVVNMFPHTSHVESMAVFERD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: MVP1_YEAST
Sequence: MDNYEGSDPWNTSSNAWTKDDDHVVSTTNSEPSLNGISGEFNTLNFSTPLDTNEEDTGFLPTNDVLEESIWDDSRNPLGATGMSQTPNIAANETVIDKNDARDQNIEESEADLLDWTNNVRKTYRPLDADIIIIEEIPEREGLLFKHANYLVKHLIALPSTSPSEERTVVRRYSDFLWLREILLKRYPFRMIPELPPKRIGSQNADQLFLKKRRIGLSRFINLVMKHPKLSNDDLVLTFLTVRTDLTSWRKQATYDTSNEFADKKISQEFMKMWKKEFAEQWNQAASCIDTSMELWYRITLLLERHEKRIMQMVHERNFFETLVDNFSEVTPKLYPVQQNDTILDINNNLSIIKKHLETTSSICKQETEEISGTLSPKFKIFTDILLSLRSLFERYKIMAANNVVELQRHVELNKEKLESMKGKPDVSGAEYDRIKKIIQKDRRSIIEQSNRAWLIRQCILEEFTIFQETQFLITRAFQDWAKLNSNHAGLKLNEWEKLVTSIMDMPISRE
What is the function of this protein?
Required for vacuolar protein sorting.
What are the official names of this protein?
Sorting nexin MVP1.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DCR1B_MOUSE
Sequence: MNGVVIPQTPIAVDFWSLRRAGSARLFFLTHMHCDHTVGLSSTWARPLYCSPITACLLHRRLQVSKHWIRALEVGESHVLPLDEIGQETMTVTLIDANHCPGSVMFLFEGYFGTILYTGDFRYTPSMLKEPALILGKQIHTLYLDNTNCNPALVLPSRQEATQQIVQLIRQFPQHNIKIGLYSLGKESLLEQLALEFRTWVVLSPQRLELVQLLGLADVFTVEEEAGRIHAVDHTEICHSAMLQWNQSHPTIAIFPTSRKVRSPHPSIYTVPYSDHSSYSELRAFVAALRPCQVVPIVHQKPCGEFFQDSLSPRLAMPLIPHSVQQYMSSSSRKTNVLWQLERRLKRPRTQGVVFESPEEKANQVKVDRDSKKHKKENLSPWAGHLERLCPHPLQARKQLFPDFCRKERDEPVLFCDSNKMATVLTAPLEFSVQLQPIDEFLFPETREKIGLESPLLSRGDSGSPARGNQSDCVGCGSPPAHISRAVPLTPESRGLALKYLLTPVHFLQAGFSSRNFDKQVEKHQRVQRSSPAVLSPVDVG
What is the function of this protein?
5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase.  Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse.  Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways.  Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase (TOP1, TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology.  Also involved in response to DNA damage: plays a role in response to DNA interstrand cross-links (ICLs) by facilitating double-strand break formation.  In case of spindle stress, involved in prophase checkpoint.  Possesses beta-lactamase activity, catalyzing the hydrolysis of penicillin G and nitrocefin (By similarity).  Exhibits no activity towards other beta-lactam antibiotic classes including cephalosporins (cefotaxime) and carbapenems (imipenem) (By similarity).
What are the official names of this protein?
5' exonuclease Apollo, Beta-lactamase MBLAC2, DNA cross-link repair 1B protein, SNM1 homolog B.
What is the protein family that this protein belongs to?
Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
What are the subcellular locations of this protein?
Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Mainly localizes to telomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome.
Protein: MPG1_DEBHA
Sequence: MKGLILVGGYGTRLRPLTLTLPKPLVEFGNRPMILHQIEALAKAGVTDIVLAVNYRPEVMVSTLKKYEAEYGVTITFSVEEEPLGTAGPLKLAEKVLKKDDTPIFVLNSDVICDYPFQELADFHKTSGGKATIVATKVDEPSKYGVIVHDRDTPNLIDRFVEKPVEFVGNRINAGLYILNPSVIDLIEMKPTSIEKETFPILVENKELYSFDLEGYWMDVGQPKDFLSGTVLYLTALSKKEPKKLCNEKFIHGGNVLVDPSAKIHPSALIGPNVVIGPNVVVGEGARIQRSVLLSNSEVKDHAWVKSTIVGWNSRIGKWARTDGITVLGDDVEIKNEVYVNGAKVLPHKSISSNVEHEAIIM
What is the function of this protein?
Involved in cell wall synthesis where it is required for glycosylation.  Involved in cell cycle progression through cell-size checkpoint (By similarity).
What are the official names of this protein?
Mannose-1-phosphate guanyltransferase, ATP-mannose-1-phosphate guanylyltransferase, GDP-mannose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM16_EMENI
Sequence: MAHRIVTQVVVTGARVFGRAFAEAYKQASAASKYQQKTGKSAGGSSSSGITLDEACKILNVKPPQAGETNLEQVMERFKKLFDLNDPQKGGSFYLQSKILRARERIEAEVREAERKAAHEKELKEGWKPKVYKDR
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  In the complex, it is required to regulate activity of mtHSP70 (SSC1/sscA) via its interaction with PAM18/TIM14.  May act by positioning PAM18/pamR in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim16, Presequence translocated-associated motor subunit pam16.
What is the protein family that this protein belongs to?
Belongs to the TIM16/PAM16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: RS10_BRASB
Sequence: MNGQNIRIRLKAFDHRILDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRSPHVDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GRAR_STAA9
Sequence: MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSRDNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIILEILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).  Upon phosphorylation by GraS, functions as a transcription regulator by direct binding to promoter regions of target genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis.  Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis.
What are the official names of this protein?
Response regulator protein GraR, Glycopeptide resistance-associated protein R.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERDL4_ARATH
Sequence: MSFRDDNTEEGRNDLRRPFLHTGSWYRMGSRQSSMLESSQVIRDSSISVLACVLIVALGPIQFGFTCGYSSPTQAAITKDLGLTVSEYSVFGSLSNVGAMVGAIASGQIAEYVGRKGSLMIAAIPNIIGWLSISFAKDTSFLYMGRLLEGFGVGIISYTVPVYIAEIAPQTMRGALGSVNQLSVTIGIMLAYLLGLFVPWRILAVLGVLPCTLLIPGLFFIPESPRWLAKMGLTDDFETSLQVLRGFETDITVEVNEIKRSVASSSKRSAVRFVDLKRRRYYFPLMVGIGLLALQQLGGINGVLFYSSTIFESAGVTSSNVATFGVGVVQVVATGIATWLVDKAGRRLLLMISSIGMTISLVIVAVAFYLKEFVSPDSNMYNILSMVSVVGVVAMVISCSLGMGPIPWLIMSEILPVNIKGLAGSIATLLNWFVSWLVTMTANMLLAWSSGGTFTLYALVCGFTVVFVSLWVPETKGKTLEEIQALFR
What is the function of this protein?
Sugar transporter.
What are the official names of this protein?
Sugar transporter ERD6-like 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL15_SHEHH
Sequence: MRLNTLSPAAGAKSAAKRVGRGIGSGTGKTCGRGHKGQKSRSGGGVRVGFEGGQMPLKIRLPKFGFTSRKALVSAEIRISELAKVNGDVIDLNALKDANLVTRNIQFAKIVLSGTIERPVTVKGLKVTQGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: METH_VIBVY
Sequence: MGSNIRAQIEAQLKQRILLIDGGMGTMIQGYKLQEQDYRGERFADWHSDLKGNNDLLVLTQPQLIKEIHHAYLEAGADILETNTFNATTIAMADYDMESLSEEINFAAAKLAREAADEWTAKNPAKPRYVAGVLGPTNRTCSISPDVNDPGYRNVSFDELVEAYSESTRALIRGGSDLILIETIFDTLNAKACAFAVESVFEELGFALPVMISGTITDASGRTLSGQTTEAFYNSLRHVRPISFGLNCALGPDELRPYVEELSRISETFVSTHPNAGLPNAFGEYDLSPEEMAEHVKEWAQSGFLNLIGGCCGTTPEHIRHMAMAVEGESPRVLPEIPVACRLSGLEPLTIAKDTLFVNVGERTNVTGSARFKRLIKEELYDEALDVAREQVENGAQIIDINMDEGMLDAEACMVRFLNLCASEPEISKVPIMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFVEQAKLIRRYGAAVIVMAFDEVGQADTRERKLEICTKAYRILVDEVGFPPEDVIFDPNIFAVATGIDEHNNYAVDFIEAVADIKRDLPHAMISGGVSNVSFSFRGNNYVREAIHAVFLYHCFKNGMDMGIVNAGQLEIYDNVPEKLREAVEDVVLNRRDDATERLLEIAEEYRENAVGKQEDASALEWRTWSVEKRLEHALVKGITEFIVEDTEEARLNASKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAHLEPFINASKQVGSSNGKILLATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVPCEQILKVAKEQQVDIIGLSGLITPSLDEMVHVAKEMERLGFDLPLLIGGATTSKAHTAVKIEQNYSHPVVYVNNASRAVGVCTSLLSDELRPAFVERLQADYELVRDQHNRKKPRTKPVTLEAARANKVAIDWQSYTPPAPSQPGVHVFDDFDVATLRQYIDWTPFFLTWSLVGKYPTIFEHEEVGEEAKRLFEDANEWLDRIEQEGLLKARGMCGLFPAASVGDDIEVYTDESRTQVAKVLHNLRQQTEKPKGANYCLSDYVAPKESGKKDWIGAFAVTGGVNERELADQFKAQGDDYNAIMIQAVADRLAEAFAEYLHERVRKEIWGYAADENLSNEELIREKYQGIRPAPGYPACPEHTEKGPLWELLNVEETIGMSLTSSYAMWPGASVSGWYFSHPDSRYFAIAQIQQDQVESYAKRKGWDLLEAEKWLGPNING
What is the function of this protein?
Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine.  Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity).
What are the official names of this protein?
Methionine synthase, 5-methyltetrahydrofolate--homocysteine methyltransferase, Methionine synthase, vitamin-B12 dependent, MS.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 dependent methionine synthase family.
Protein: GLND_BURO1
Sequence: MSAHAAPSPEALSRRAEFKAAKTEMLERFRHAANVASLMHALSKLTDDALKRVWDECGLPATLALVAVGGYGRGELAPYSDVDILVLLPDAHDAALDARIERFIGMAWDLGLEIGSSVRTVAQCIEEASQDVTVQTSLLEARRIVGSTALFERFTVRYHEALDARAFFTAKVLEMRQRHAKFQDTPYSLEPNVKESPGGLRDLQTILWIARAAGFGSSWRELDTRGLITDREARELRRNEGFLKTLRARLHVIAGRRQDMLVFDLQTQAAESFGYQPTQAKRASEQLMRRYYWAAKAVTQLATILIQNIEAQLFPATSGITRVLSADRFVEKQGMLEIVDDGVFERHPDAILEAFLLYETTRGVKGLSARTLRALYNSREIMNNAWRRDPQNRATFMRILQQPEGITHAFRLMNQTSVLGRYLLNFRRIVGQMQHDLYHVYTVDQHILMVLRNIRRFAVAEHAHEYPFCSQLIGNFERPWVLYVAALFHDIAKGRGGDHSTLGMADARRFCREHGIAGDDAALIVWLVQHHLTMSQVAQKQDTSDPEVIKRFAEVVGNERYLTALYLLTVADIRGTSPKVWNTWKGKLLEDLYRITLAVLGGANPDAHSELKSRQEQALALLRLETVPDDAHRALWDQLDVGFFLRHDAADIAWQTRVLYRHVNAETAIVRARPSPIGDALQVLVYVKDRPDLFAGICAYFDRNGLSVLDARVSTTRHGYALDNFIVTQTERDVRYRDIANLVEQQLATRLAETASLPEPSKGRLSRLSRTFPITPRVDLRADERGQYYILSVSANDRPGLLYSIARVLAEHRIGVHAARINTLGERVEDIFLLAGAGLSDNRLQIQLETELLRAIAV
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: EED1_CANAL
Sequence: MERRQFNTSNIRNGTGRPRKTPRSKLYMVYPPLSGEDSTNPEPEEGSSQENNPTEPSSSQSNSVQNQDQSEDQSQLPQQESNTQQESNTQQESNTPSPRASNTSTETPAPLSPIQPGIRNIPSGLLLPQEKVGRLMGYPFYRDFNFTLNPERYQKLIYVFQILKNAARNHRNGASLLRKYFSLARRSKRTTDMFVTTIEEMRKRSLENSRKRELEEAQEREESNKRQHTESSAEPNAESSTESTTESNAESGAEPNAEPSAESTTESNVESGAEPNAESGAESGAEPTAESNAELKQRIWEILSYRLEQSNNETNNTGESNSTSQQPRQLPNNELIMNIRVLQKNTHAKPVLGRIKFTPDKSNKTSLTGSQNKVHSTNTQQSQKHPQQILTNSETHKPQQYSAQSQQQMVHQTNSHEPSQKRSPPPQQQQQKQPSVPTSSVPLQVSQKQNQQQQELPLPPQPQPQQRTAPSAVKQQQSMQMQPPPQQQQQQQRHQPLQQSPPTMPLQQQPVPPVQQVQTVPPPSSQPQTQLSQQQQQQQQAQLQMQVPRCYQYQNRPPSQQRQYSQTPQYNQPPPQQKVYALPPQQVYAPPPRQVYAQPTIACKQQYPQQLYEQAPQEGSSYQHHYQQVQQRQNQQPYMQSAPTYQQPHVQTPKSTRSNKQEKQRLPKGQEQVPKATRTMFEAFTGSNIAVEKLRQRTLDNGREPERLRTEYVNVLSSPERAAEKSTSRSKQSSNQKPVVKQQSSFPPPIKHQQTQEQQGNILPPVSQLLAIQSSTVTSRGSNASGAVMGSGNTQRVASRSFTNTFVAEAVVNNANNRGGPVPPTGPETNTRGGRASTRSSGRPRGNRSTQRAEGNVTGRVARSTDGSQSQNSGKASKISNIRNLLN
What is the function of this protein?
Transcriptional regulator involved in extension of germ tubes into elongated hyphae and maintenance of filamentous growth.  Regulates expression of UME6.  Acts in a pathway that regulates maintenance of hyphal growth by repressing hyphal-to-yeast transition and allows dissemination within host epithelial tissues.  Dispensable for invasion into both host oral epithelial cells and enterocytes, but required for epithelial damage.
What are the official names of this protein?
Transcriptional regulator DEF1, EFG1-dependent transcript protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: KPBB_RABIT
Sequence: MAGATGLMAEVSWKVLERRARTKRSGSVYEPLKSINLPRPDNETLWDKLDYYYKIVKSTLLLYQSPTTGLFPTKTCGGDQTAKIHDSLYCAAGAWALALAYRRIDDDKGRTHELEHSAIKCMRGILYCYMRQADKVQQFKQDPRPTTCLHSLFNVHTGDELLSYEEYGHLQINAVSLYLLYLVEMISSGLQIIYNTDEVSFIQNLVFCVERVYRVPDFGVWERGSKYNNGSTELHSSSVGLAKAALEAINGFNLFGNQGCSWSVIFVDLDAHNRNRQTLCSLLPRESRSHNTDAALLPCISYPAFALDDDVLYNQTLDKVIRKLKGKYGFKRFLRDGYRTSLEDPKRRYYKPAEIKLFDGIECEFPIFFLYMMIDGVFRGNPKQVKEYQDLLTPVLHQTTEGYPVVPKYYYVPADFVEYEKRNPGSQKRFPSNCGRDGKLFLWGQALYIIAKLLADELISPKDIDPVQRYVPLQNQRNVSMRYSNQGPLENDLVVHVALVAESQRLQVFLNTYGIQTQTPQQVEPIQIWPQQELVKAYFHLGINEKLGLSGRPDRPIGCLGTSKIYRILGKTVVCYPIIFDLSDFYMSQDVLLLIDDIKNALQFIKQYWKMHGRPLFLVLIREDNIRGSRFNPMLDMLAALKNGMIGGVKVHVDRLQTLISGAVVEQLDFLRISDTEELPEFKSFEELEPPKHSKVKRQSSTSNAPELEQQPEVSVTEWRNKPTHEILQKLNDCSCLASQTILLGILLKREGPNFITQEGTVSDHIERLYRRAGSKKLWLAVRYGAAFTQKFSSSIAPHITTFLVHGKQVTLGAFGHEEEVISNPLSPRVIKNIIYYKCNTHDEREAVIQQELVIHIGWIISNNPELFSGMLKIRIGWIIHAMEYELQIRSGDKPAKDLYQLSPSEVKQLLLDILQPQQNGRCWLNKRQIDGSLNRTPTGFYDRVWQILERTPNGIIVAGKHLPQQPTLSDMTMYEMNFSLLVEDMLGNIDQPKYRQIVVELLMVVSIVLERNPELEFQDKVDLDKLVKEAFHEFQKDESRLKEIEKQDDMTSFYNTPPLGKRGTCSYLTKVVMNLLLEGEVKPSNEDSCLVS
What is the function of this protein?
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.  The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
What are the official names of this protein?
Phosphorylase b kinase regulatory subunit beta, Phosphorylase kinase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the phosphorylase b kinase regulatory chain family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: MIAA_PEDPA
Sequence: MEKVLAIVGPTAVGKTNLSIDIAKKFNGEIISGDSMQVYQKLDIGTAKVTIEEMQGIPHHLIDTKTIHDRFSAADFKETAQKLISEISQRGKLPIVVGGTGFYLQALLRDLELGGSNEDRNQIEAIRTELNQKENDELLSILKTIDLATYENIDRKNRRRIIRAIEVFKVSGQKMSEQQMQPTAVYDDLLIGLNTERSILYQRINHRVNMMLDAGLENEARWLFDETKVPQANKGIGYREWQDYFKNEKTLSETIELIQKDSRHYAKRQLTWFRNKMDVNWYDIIQNPQEQAKIYQKIENWLGVKNELER
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RNLE_SOLLC
Sequence: MASNSAFSLFLILLIITQCLSVLNAAKDFDFFYFVQQWPGSYCDTKQSCCYPTTGKPAADFGIHGLWPNNNDGTYPSNCDPNSPYDQSQISDLISSMQQNWPTLACPSGSGSTFWSHEWEKHGTCAESVLTNQHAYFKKALDLKNQIDLLSILQGADIHPDGESYDLVNIRNAIKSAIGYTPWIQCNVDQSGNSQLYQVYICVDGSGSSLIECPIFPGGKCGTSIEFPTF
What is the function of this protein?
Probably involved in plant phosphate-starvation rescue system.
What are the official names of this protein?
Extracellular ribonuclease LE, RNase LE.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Secreted, cell wall.
Protein: PXT1_MOUSE
Sequence: MQLRHIGDSVNHRVIQEHLAQEVGDVLAPFVALVFVRGQVLLRFFWNNHLL
What are the official names of this protein?
Peroxisomal testis-specific protein 1, Small testis-specific peroxisomal protein.
What are the subcellular locations of this protein?
Peroxisome.