PharMolix/UniProtQA huggingface dataset:
Protein: CH3L1_PIG
Sequence: MGLRVAQTGFVALVLLQSCAAYKLVCYYTSWSQYREGDGSCFPDAIDPFLCTHIIYSFANISNNEIDTWEWNDVTLYDTLNTLKNRNPNLKTLLSVGGWNFGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGRRDKRHLTTLVKEMKAEFIREAQAGTEQLLLSAAVSAGKVAIDRGYDIAQISQHLDFISLLTYDFHGAWRQTTGHHSPLFRGQEDASSDRFSNADYAVSYVLRLGAPANKLVMGIPTFGRSFTLASSKTDVGAPVSGPGIPGRFTKEKGILAYYEICDFLQGATTHRFRDQQVPYATKGNQWVGYDDQESVKNKAKYLKSRQLAGAMVWALDLDDFRGNFCGQNLRFPLTSAIKDVLAAA
What is the function of this protein?
Carbohydrate-binding lectin with a preference for chitin.  Has no chitinase activity.  May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment.  Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation.  Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs.  Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells.  Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance.  Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung (By similarity).  Stimulates migration and adhesion of cultured vascular smooth muscle cells.
What are the official names of this protein?
Chitinase-3-like protein 1, 38 kDa heparin-binding glycoprotein, Signal-processing protein, gp38k.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum.
Protein: CC153_DANRE
Sequence: MPPKKKGIGGSKKEKTKKSTPEKDDGLTEKYRRSVLDVSVLKEHLALRSGVARQATAVRDELKSQVRDLEQLLSQERSDMKDITADLNRQYKSMETDLQSKADKLEASVDLLEKQLAECQVELKSERELRENTEAEKDAIISDLQSKLDSMERECEKILHGCLDSLLSHLADTRMKWEEQSTVIHQDVKDMLREFGINPLHM
What are the official names of this protein?
Coiled-coil domain-containing protein 153.
What is the protein family that this protein belongs to?
Belongs to the UPF0610 family.
Protein: DEOC_THET2
Sequence: MDLAAHIDHTLLKPTATPEEVAKAAEEALEYGFYGLCIPPSYVAWVKARYPHAPFRLVTVVGFPLGYQEKEVKALEAALACARGADEVDMVLHLGRAKAGDLDYVEAEVRAVREAVPKAVLKVILETGYFSPEEIARLAEAAIRGGADFLKTSTGFGPRGASLEDVALLVRVAQGRAQVKAAGGIRDRETALRMLKAGASRLGTSSGVALVAGEGGTLGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_LEPIC
Sequence: MNGDIAVFAGNSNKQIAEEICTHLGIQSGKINLKKFSDGEISVKIEDNVRGKEVFIVQSTSAPANDHLMELILIMDALRRASVSSISVVIPYYGYGRQDRKVEPRVPISARVVADLIEVVGLDRILTMDLHADQIQGFFRVPVDNLHFAPVLAEYVNTKKIDDLVIVSPDSGGAERARAFGKKVNGSLAIIDKRRPKANVSEVMNVIGEIEGKNCILLDDMIDTAGTICKAADVLLKHGAKSVYCAATHGVLSGEAVDRINSTQFSEVVLANTIAIPESKKINKLKSLSVAPLFANAIQRIHTNQSVSTLFD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_XANC5
Sequence: MFQGETAITVDDKGRMAVPTAYRDLVARVSGNRLVLTYNPFEAGCLWLYAEKEWERVRDDVMSKPNTQRVVRTLQQKLVGSSAVLELDANGRLSIPASHRNAVGIEKKAVLLGMGDKFELWSEQAHRALIQQTLSDGDLGDELLDLRL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YKQC_SCHPO
Sequence: MSEEESPYQLTKTFSNPKNNKIGLAIFLIGAFINLIHIYKPKGPSNNPTKRNYHISFGPPGKIRWFPLGIRKEVRSNVSGREIIIKMIITFILVQTTLITLDLYVFGATGLGLILSWKLFEVACANPEDEALLAERKQRLKEQREKKEQKKEQKKEKKTERRKKKKL
What are the official names of this protein?
Uncharacterized protein C688.12c.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: ACN2_ACAGO
Sequence: DVYKGGGGGRYGGGRYGGGGGYGGGLGGGGLGGGGLGGGKGLGGGGLGGGGLGGGGLGGGGLGGGKGLGGGGLGGGGLGGGGLGGGGLGGGKGLGGGGLGGGGLGGGRGGYGGGGYGGGYGGGYGGGKYKG
What is the function of this protein?
Antimicrobial protein.  Strong activity against the Gram-negative bacterium E. coli SBS363 and yeast C. albicans.  No detectable activity against the Gram-positive bacterium M. luteus.
What are the official names of this protein?
Acanthoscurrin-2.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_XYLFM
Sequence: MARYIGPSCKLARREGADLSLKSPSRALDSKCKLEQRPGQHGAVRKSKLSDYASQLREKQKVKRIYGVLERQFRNYYKNASTKKGNTGENLLQLLETRLDNVIYRMGFAVTRPAARQLVSHRGVLVNGKIVNLPSYHVKPGDIVALSQRAQKYLCVQESLTIKDQHGSAFSWVEVDSEKFSGVFKALPDRADLPSDINEALIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CLPS_YERPY
Sequence: MGKNNDWLNFEHLVKDKQIEALQPPSMYKVILNNDDYTPMEFVIDVLQKFFSYDIERATQLMLNVHYQGKAICGVFTAEVAETKVAHVNQYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: SYFA_BACMK
Sequence: MEARLKELKQKALELIEEAKELKGLNDVRVAYLGKKGPITEVLRGMGKLSAEERPRMGALVNEVREAIQTRLEDKIGNLEKAVIEAKLATETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFYITEETLLRTHTSSVQARTMEKNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFGEDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAMLKYGVDDIRHFYTNDVRFLQQFKRA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_MYCPA
Sequence: MTGAVCPGSFDPVTLGHVDVFERASAQFDEVVVAILTNPAKKGMFDLDERIAMIEESTTHLSNLRVEAGQGLVVDFVRSRGMTAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNRRLREKLSGRS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_DICNV
Sequence: MTMSNYQRQLFAKHQQLHALLRPFSAPKIRIYPSPEKHYRMRAEFRIWRDDEQLFYAMSRGGALTAQNIVRLHNFPPAYITIDRCMPLLLDALRADPVLHHKLYEVHFLASLRGELLVSLIYHRALTDEWTAAAKALAKRFHILLIGRSRKQKITLERDFILETLNVDGRAFHYHQYEQSFSQPNAYVCQKMLRWACAQAGENAGDLLELYCGNGNFTLPLASHFRRVLATEISKSSITALQENIFLNQTNNIAVARLSAEEFTQAWQKERDFYRLKQAGIELADYQFETVFVDPPRAGIDDNTLFLLQKFPKIIYISCNPHTLAANLQTLTQTHELCAAALFDQFPDTPHIECGVVLRKK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: HGD_RHOPB
Sequence: MNITTAPGLIGRSTQAITPGYMSGFGNSFETEALPGALPIGRNSPQRAPYGLYAEQLSGSPFTAPRGSNERSWLYRIRPSVQHSGRFEKAEAGLWRSAPCHEHDMPIAQLRWDPPPLPQRAQTFLQGVETMTTAGDVNTQAGMAAHMYLISASMVNQHFYNADGELMFVPQQGGLRLVTEFGVIGVAPGEIAVIPRGVKFRVELIDGPARGYLCENYGGGFTLPERGPIGANCLANARDFLTPVAAYEDSDTPTELYVKWGGALWVTQLPHSPIDVVAWHGNYAPYKYDLRTFSPVGAIGFDHPDPSIFTVLTSPSETAGTANIDFVIFPERWMVAENTFRPPWYHMNIMSEFMGLIYGVYDAKPQGFLPGGASLHNMMLPHGPDREAFDHASNAELKPVKLEGTLAFMFETRYPQRVTVHAATSSTLQADYAECWRGLQKRFDPTKP
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: KITH_THEKO
Sequence: MKPMHPGGFLEVITGPMFAGKTTELIKRVERQIFAKRKAALFKPAIDNRYSEREVVAHNGLRYEAFVVPTTEKGVERIKEITLNEGYEVIGIDEVQFFPMSVVEALNELADQGIYVIASGLNLDFKGDPFPVTKELLVRADNIVYLTAVCTVCGKPATRSQRLIDGKPAPRNSPVILVGGRESYEARCREHHLVPDE
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPY6R_HUMAN
Sequence: MEVSLNHPASNTTSTKNNNSAFFYFESCQPPSPALLLLCIAYTVVLIVGLFGNLSLIIIIFKKQRKAQNFTSILIANLSLSDTLVCVMCIHFTIIYTLMDHWIFGDTMCRLTSYVQSVSISVSIFSLVFTAVERYQLIVNPRGWKPSVTHAYWGITLIWLFSLLLSIPFFLSYHLTDEPFRNLSLPTDLYTHQVACVENWPSKKDRLLFTTSLFLLQYFVPLGFILICYLKIVICLRRRNAKVDKKKENEGRLNENKRINTMLISIVVTFGACWLPRISSMSSLTGIMRC
What is the function of this protein?
When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function.
What are the official names of this protein?
Putative neuropeptide Y receptor type 6, NPY6-R, NPY Y1-like receptor, Putative pancreatic polypeptide receptor 2, PP2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PPM1K_BOVIN
Sequence: MSTAALLTLVRSGGNQVRRRVLLRARGLQDDRWVMPTCHSSTSEPKWSRFDPDGSGRPATWDNFGIWDNRLEEPILLPPSIKYGKPIPKVSLQNVGSASQIGKRKENEDRFGFAQLTNEVLYFAVYDGHGGPAAADFCHTHMEKCILDLLPKEENLETVLTLAFLEIDKTFARHAHLSADATLLTSGTTATVALLRDGIELVIASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSLGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNTTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA
What is the function of this protein?
Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development.
What are the official names of this protein?
Protein phosphatase 1K, mitochondrial, Protein phosphatase 2C isoform kappa, PP2C-kappa.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ARGR2_STRP1
Sequence: MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRDLREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVLANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPI1_YEAS7
Sequence: MTKSRKQKQKKQDFLRKKLKVGKPKEKARNATDTSFVSKTISIRNQHLDQNPHDLTKRLTLLKHHNINVRKETLTTFQKSIPSIIKSRLMTPLLTQSIPLICDESQQVRQGLIDLVDEIGSHDAEILKLHCNIFVLYINMAMTHIVTQIQADSTKFLSHLLKYCGDEVVRKSWVKLLNGVFGVLGWGQVGKNDSASIVQTKKRNAKYVTIHLNALYTLVEYGCQDERARSDGDTAETTEDSGTLRNPYLIPDYPQPFEHLKLFTRELKVQDATSSGVNATLLSLATQDIDTRKAVFIEQFLPIVRKKIEVIIKEGGECGKSANKLKTLLAKIFD
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein IPI1, Involved in processing IST2 protein 1.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ETF2_VAR67
Sequence: MRYIVSPQLVLQVGKGQEVERALYLTPYDYIDEKSPIYYFLRSHLNIQQPEIVKRHILLTLRMTQLKGYLGNLLDIKDDIIIYSHKNNLEYSYVDNTIFNPFVYTQKKTLLKNDSFLYNVYPGACDFLVIWVARACDTSIPEFGSYEDVDNNIIKFETMLMDVFPQLDLDITVESKFNNIFRTNLKLTGLKKIIQRVQDLDINYKSLLSRYDEHFINMTGNHFILNDEQLNLSIWDLDGTLALSSDGDTVMINNVKLFTDLVSDIDTQMERIKGDITYKVHLATPINSRIKLDIETSFIFIETATNNILLSSDKKISIILAKNHISIKVKNHIPNIEKYFTFLVIAINAMFNSVQKSADFTKVETVYWSRICQNTKNKNRKPVIINYLDPGMKKISNNFYRSDEKEVFINDNDIMFTCMDPLGKYNKVGFLNIFHDMRKYCIPCCFLHDQSHRSTFSSCVHQIDVEKKIVSPYILNFGKVVTESKMSFLPIIFDAFLNDGMTANMEQDNKRLKETSGYHIVRCCTGNDIVRLRTTSNIIQFVNEDKNILIVNDMVYFPMNASDIGKKIHILIQEIVHEVMIVKKKESSDKIDFFPPNYKLLKDLFPKQTIQTPIQSDAGMVLTTDGFYIDGKLFNEDLSSKYVTFTKNVITSDAVAKYFSPLFKYVISEAKDRFIKTWMINIMIHMNVDPNNIIPTLEKYYPNFGRVQIN
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from early gene promoters.  Is recruited by the RPO-associated protein of 94 kDa RAP94/OPG109 to form the early transcription complex, which also contains the core RNA polymerase.  ETF heterodimer binds to early gene promoters.
What are the official names of this protein?
Early transcription factor 82 kDa subunit, ETF large subunit, VETF A7 subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae VETF large subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: SCG3_HUMAN
Sequence: MGFLGTGTWILVLVLPIQAFPKPGGSQDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEDPNKPTSWTENQAGKIPEKVTPMAAIQDGLAKGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNISKLFPAPSEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL
What is the function of this protein?
Member of the granin protein family that regulates the biogenesis of secretory granules (PubMed:19357184).  Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (By similarity).  May also play a role in angiogenesis.  Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (PubMed:29154827).
What are the official names of this protein?
Secretogranin-3, Secretogranin III, SgIII.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts.
Protein: CXA1_DANRE
Sequence: MGDWSALGRLLDKVQAYSTAGGKVWLSVLFIFRILVLGTAVESAWGDEQSAFKCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSTPTLLYLAHVFYLMRKEEKLNRKEEELKAVQNDGGDVELHLKKIELKKFKHGLEEHGKVKMKGSLLRTYIFSIIFKSICEVVFLVIQWYLYGFSLSAVYTCERTPCPHRVDCFLSRPTEKTIFIIFMLVVSLFSLLLNIIELFYVLFKRIKDRVKSRQNTQFPTGTLSPTPKELSTTKYAYYNGCSSPTAPLSPMSPPGYKLATGERTNSCRNYNKQANEQNWANYSTEQNRLGQNGSTISNSHAQAFDYPDDTHEHKKLTPGHELQPLALIDARPCSRASSRMSSRARPDDLDV
What is the function of this protein?
Plays a role in regulation of fin bone size and growth.
What are the official names of this protein?
Gap junction alpha-1 protein, Connexin-43, Cx43, Short fin protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Note=Localizes at the intercalated disk (ICD) in cardiomyocytes and proper localization at ICD is dependent on TMEM65.
Protein: YI44_SCHPO
Sequence: MNLVQLGKLHENVLDAGCEPNRNARYLASLGYKVVGIDISERAISKAIDKTSSEKSNVNFNQRDFSRLNEFKGHFDTVIDIGCFHSILNSDHEPYTASLSHICHSDSSVFLRAFSETNKSRYRRWQGHKRYSLALKRNNVKKLSL
What is the function of this protein?
Probable methyltransferase.
What are the official names of this protein?
Uncharacterized methyltransferase C1348.04.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: MLAA_HAEIN
Sequence: MKTKTILTALLSAIALTGCANNNDTKQVSERNDSLEDFNRTMWKFNYNVIDRYVLEPAAKGWNNYVPKPISSGLAGIANNLDEPVSFINRLIEGEPKKAFVHFNRFWINTVFGLGGFIDFASASKELRIDNQRGFGETLGSYGVDAGTYIVLPIYNATTPRQLTGAVVDAAYMYPFWQWVGGPWALVKYGVQAVDARAKNLNNAELLRQAQDPYITFREAYYQNLQFKVNDGKLVESKESLPDDILKEID
What is the function of this protein?
Involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane.
What are the official names of this protein?
Intermembrane phospholipid transport system lipoprotein MlaA.
What is the protein family that this protein belongs to?
Belongs to the MlaA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: FER3L_MOUSE
Sequence: MAAYPESCLDATVLNFVADLSLASPRHPLLCEFPPGVPFGDRTLGYREGRPGRLSQFDERYQEVEGDEVEYEDPEEEEEEGEGRGRVASLLGRPKRKRVITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLQSKEEKEAS
What is the function of this protein?
Transcription factor that binds to the E-box and functions as inhibitor of transcription.  DNA binding requires dimerization with an E protein.  Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins.
What are the official names of this protein?
Fer3-like protein, Basic helix-loop-helix protein N-twist, Nephew of atonal 3, Neuronal twist.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMA_CALS8
Sequence: MKKKVLVAMSGGVDSSVAAAILKEEGYEVYGATMQIWQNECGEELITGKSCCSIYAVDDARKVANILDIPYYVFNMKDDFRKIVIDYFIDEYIKGRTPNPCIMCNRKIKFELFLKKAIAIGMDYIATGHYAIIEYDSSLNRYLLKRSKAKEKDQTYVLYNMTQEMLSKTLFPLGRFSKDEVRKLAEKFKLPVAKKPDSQEICFIPDNNYGKFIEKETGIREDGVYVDTEGNILGKSKAYYNYTIGQRKGLGISTGKRMYVVAIKPEENKVVLGEEGKIFADALIATDLNFIPFDKLESEIEVTAKIRYTAKEAKAKIVPMENNKVLVKFYEKQRAITPGQSVVFYNNDIVVGGGIIEKALV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHM_NOSS1
Sequence: MENATLLKSTTRHIRIFAAEIDRDGELVPSNQVLTLDIDPDNEFNWNEDALQKIYRKFDELVEASSGADLTDYNLRRIGSDLEHYLRSLLQKGEISYNLSARVTNYSLGLPQVAVEDK
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit M, NAD(P)H dehydrogenase I subunit M, NDH-1 subunit M, NDH-M.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhM subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FGF2_CAVPO
Sequence: VGGRGRGRGTAAAARREPGGAMAAGSITTLPALPEGGDGGAFAPGHFKDPNGGFFLRIHPDGRVDGVREKTDPHIKLQLQAEDRGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
What is the function of this protein?
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).  Also acts as an integrin ligand which is required for FGF2 signaling (By similarity).  Binds to integrin ITGAV:ITGB3 (By similarity).  Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity).  Functions as a potent mitogen in vitro (By similarity).  Can induce angiogenesis (By similarity).  Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity).
What are the official names of this protein?
Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2, Prostatic growth factor.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism (By similarity). Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol (By similarity). Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity).
Protein: LEUC_BIFA0
Sequence: MGMTLAEKVWADHLVRKGSDGAPDLLYIDLMLMHEVTSPQAFEGLRLAGRTPRHLDQLIATEDHNTPTVDIDKPNPDETSATQLTTLEKNCREFGVRLHPLGDADQGIVHAFAPMLGLTQPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVMATQTLSLKPFKTMAINIEGDLPAGVSAKDIILAIIAKIGTGGGQGYVLEYRGRAIEQLSMDARMTICNMSIEAGARAGMIAPDETTFAYLKGRPHAPKGEMWDQAVEYWKTLRTDDDAVFDAEVTLRAEDLEPFVTWGTNPGQGVAISGVVPAPDDFADATERSAAERALDYMGLEPGTPIRDIPVDTVFIGSCTNGRIEDLRIAAEIMKGHKKADSIHRVLVVPASSRIRLQAEREGLDRIFKDFGAEWRNAGCSMCLGMNPDKLVAHERSISTSNRNFEGRQGKGSRTHLASPAVAAATAIRGTISTPADL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SYGA_PROM1
Sequence: MYFQDIISNLNNFWSEKGCLLLQPYDLEKGAGTMSPHSFLRAIGPEPWAVAYPEPCRRPTDGRYGDNPNRAQHYFQYQVLIKPSLDGIQEIYLSSLEALGISAKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGLDCKPVSIEITYGLERLAMYLQNVESIWDLSWNKKTKYGDIWLPFEKGQCKYNFEESNSENLRKLFEIYEEEAHQLIAKKLPAPCLDYVLKCSHTFNLLEARGVISVTERTKIIARIRSLARKVAEAWLEERGTLGFPLCAEN
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.