PharMolix/UniProtQA huggingface dataset:
Protein: HSLV_ANAMM
Sequence: MSHRDSYTMYGTTILCIRQGGSVIIAGDGQVSMGSAIMKTSAKKIKRLAGDSVITGFAGATADAFTLFERLEAKLEKHPGQLMRACVELAKDWRRDKYLRRLEAMMIVADKSVSLIISGGGDVLEPENGIAAIGSGGNFALSAARALCAARDELSLDMTLEYIATAAMAVASEICVYTNNNIIMEKIEE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_VIBC3
Sequence: MAKLTKRMRTIRAKVDVTKEYDINEAVALLKEMATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRDIRVAVFTQGANAEAAKAAGAELVGMEDLADLVKKGEMNFDVVIASPDAMRVVGQLGTILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVTFEADQLKENLEALLVALKKAKPSSAKGVFVKKVSISTTMGAGVAVDQNTLSAQV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: SARR_STAAC
Sequence: MSKINDINDLVNATFQVKKFFRDTKKKFNLNYEEIYILNHILRSESNEISSKEIAKCSEFKPYYLTKALQKLKDLKLLSKKRSLQDERTVIVYVTDTQKANIQKLISELEEYIKN
What is the function of this protein?
Negative regulator of sarA transcription at late exponential and stationary growth phases.  It contributes to the modulation of target genes downstream of the sarA regulatory cascade.  Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarR, Staphylococcal accessory regulator R.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRCA_SERP5
Sequence: MITGIQITKANDQALVNSFWLLDDEKSEARCVCAKANYAEDQVVPVSELGQIEYREVPLEMQSTVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: PSBF_NELLU
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUOI_ECOL5
Sequence: MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKDKGEAENEAKPIDVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FCG3A_MUSPF
Sequence: MWQLLPSTALLLVASARPQAADLPKAVVVSDPPGNRVLTLDSVTFTCQGANPSGNHSTRWLHNGTLISSQTSYFIRAASVENSGEYRCQTGLSELSDPVQLEVHVGWLLLQTPQRVFQEGEPIRLRCHSWKNKPVWNVQYFQNRRGKKFSYGNSEFYIPAARSEHNGSYFCRGLIGKRNESSEAVDIIIQGPPVPSTSALLPFWPHIPFAVVMALLFAVDTGLYFAMQRHLHNSKRAWENSKVSWKQDP
What is the function of this protein?
Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG).  Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC).  Does not bind free monomeric IgG, thus avoiding inappropriate effector cell activation in the absence of antigenic trigger (By similarity).  Mediates IgG effector functions on natural killer (NK) cells.  Binds antigen-IgG complexes generated upon infection and triggers NK cell-dependent cytokine production and degranulation to limit viral load and propagation (By similarity).  Fc-binding subunit that associates with FCER1G adapter to form functional signaling complexes.  Following the engagement of antigen-IgG complexes, triggers phosphorylation of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapter with subsequent activation of phosphatidylinositol 3-kinase signaling and sustained elevation of intracellular calcium that ultimately drive NK cell activation (By similarity).  Mediates enhanced ADCC in response to afucosylated IgGs (PubMed:34485821).
What are the official names of this protein?
Low affinity immunoglobulin gamma Fc region receptor III-A, IgG Fc receptor III-A, Fc-gamma RIII-alpha, FcgammaRIIIA.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DAPEL_LACLS
Sequence: MINLIEIRRQLHQIPEIGLEEHKTQKYLLTIIHQIIQNKSFIQVETWQTGILVYLKGSQGQKTIGWRTDIDGLPVEELTNLPFASKNGRMHACGHDIHMTVALGLLEKLSESQPKNNLLFLFQPAEENEAGGKLMYDGGAFKNWLPDEFYGLHVRPDLKVGDIATNEQTLFAGTCEVELTFVGTGGHAAFPHTANDALVAAAYFVTQVQTIVSRNVDPLDSAVVTFGKMEAGTTNNIIAERAFLHGTIRSLTQEVNELTQKRLTELAKGVAQSFDMTIDLKLKQGGYLPVENNPKLAKELMDFFRNETKANLIDIAPAMTGEDFGYLLSKIPGVMFWLGINSEAPLHSQKMQADEEVLDFAVEAIGQFLDFKANRN
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: Y1533_ARCFU
Sequence: MLEILMSLTAAICWAFNGIAYRKGVKDVSAFTANFHRTLFATVYFLPLALRDFPGVVIDLQTALVLVISAMLSFYIGDLSYFASLKRSPVSIALPASSTYPVYVVLLSTVIYGAELSLNALISAILVFVAVYIIYGSGEKGETSGLFYALLAAFSWALAILTLDFLTDRLPVSIVAFVRLLLCLILLSFTAKKDELSTEIRLFFRSVRGIFLLLGIMLFITAIKVSSSWNVVQPSSTSPVFAAIFGAIFLKERISFRLVAGIFVIILAILLLLLPPLQ
What are the official names of this protein?
Uncharacterized transporter AF_1533.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPE_LEGPL
Sequence: MSITTHLDIVSAEHEIFSGVVELVVATGELGEIGITPGHAPLLTVLRPGEVRITLQGGTQDIYYVQGGMLEVQPHCVTILADVAERAEHLDEAAALAAKAKAEAAIASKGGDIDYSVAAAELARAVAQIRAIQKTRKKMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HEM1_XYLF2
Sequence: MTLWVLGLNHQTAPMELRERASFVGDALPRALDSLRNLPNVNEAALLSTCNRTELYAETTNAQMLLNWLEQHRPGLQNHLYQYRDAAAVRHLFRVATGLDSMVLGESQILGQVKDSWSMARTHGTLGNTLDRLFQHSFSVAKHARTNTRIGTNPVSIASTAVRLAQDAFSPLNESTVLLIGAGETIQLAAKHLSEGRVQRLLIANRTHAKAQMLASQHGGYALPLTELNLHLAEADIIFSATAAPTPIVTQSNVESALHIRKRKPILLFDLAIPRDIETEVGTLTDAYLYTIDDLERAVEENRHSRREAAETAEAIIELQVKRYMDTLQAQAHQAPLRRLRTFGTTTRDELLTRARRQLANGRPAEEVLEQLAHGLTNRLLHPPTAALREAALANNTELVRAAEQLFPEKPGYHHPTLQTTIVKTDETDPAS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: LPXG_CHLTR
Sequence: MFVSVGITASLTTILAAPVLTWVWANHLEPNLLRVTRLNWNLPKKFAHLHGLRIVQISDLHLNHSTPDAFLKKVSRKISSLSPDILVFTGDFVCRAKVETPERLKHFLCSLHAPLGCFACLGNHDYATYVSRDIHGKINTISAMNSRPLKRAFTSVYQSLFASSRNEFADTLNPQIPNPHLVSILRNTPFQLLHNQSATLSDTINIVGLGDFFAKQFDPKKAFTDYNPTLPGIILSHNPDTIHHLQDYPGDVVFSGHSHGPQISLPWPKFANTITNKLSGLENPELARGLFSFPEESRLLYVNRGLGGWKRIRFCSPPEICLMRCLYEP
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to form 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipooligosaccharide (LOS) to the outer membrane of the cell.  Can functionally complement lpxH deficiency in E. coli.  Overexpression of LpxG results in toxic accumulation of lipid X and profoundly reduces the infectivity of C. trachomatis.  Can utilize UDP-2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosamine as substrate in vitro, but the substrate is likely UDP-2-N-((3R)-3-hydroxyicosanoyl),3-O-(tetradecanoyl)-alpha-D-glucosamine in vivo.
What are the official names of this protein?
UDP-2,3-diacylglucosamine pyrophosphatase LpxG, UDP-DAGn pyrophosphatase, UDP-2,3-diacylglucosamine hydrolase LpxG, UDP-DAGn hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. LpxG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: KGUA_ALKCK
Sequence: MKREKGLLIVLSGPAGVGKGTVCGALRNQNTAIEYSVSATTRKPREGEKHGVNYFFKTREQFEQMIEDGKLLEWAEYVGNYYGTPIDYVQETINAGKDIILEIEVQGAQKVRTVFPEGVFIFLAPPSLKELRDRIVGRGTETEDIINERMTVAKEEIDLMTMYDYVVENDKVEWAVERIKAIVTAEHCKRERLIKKYKELVEVEK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSQ_PSEAE
Sequence: MNGVLLRHQQPGGLGRAPRKPMPRGASRLVAKEPLSVRLPKADFSFLKYLAWPLLLAVLGYGAYRGAEYILPYADRPIAKVSVEGDLSYISQRAVQQRISPYLAASFFTIDLAGMRGQLEQMPWIAHAEVRRVWPDQVVIRLDEQLPIARWGDEALLNNQGQAFTPKELANYEHLPRLHGPQRAQQQVMQQYQLLSQLLRPLGFSIARLEMSDRGGWALTTAQGVEIQIGRDHVVDKIRRFVSIYDKALKDQISNIARIDLRYPNGLAVAWREPVTPATVATASAVQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.  May control correct divisome assembly.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: MGRN1_HUMAN
Sequence: MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSLEFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDFSEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGISDGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPLGGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPALGPDSCSVGIDE
What is the function of this protein?
E3 ubiquitin-protein ligase.  Mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H.  Plays a role in the regulation of endosome-to-lysosome trafficking.  Impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production.  Does not inhibit ADRB2-signaling.  Does not promote MC1R ubiquitination.  Acts also as a negative regulator of hedgehog signaling (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase MGRN1, Mahogunin RING finger protein 1, RING finger protein 156, RING-type E3 ubiquitin transferase MGRN1.
What are the subcellular locations of this protein?
Early endosome. Note=The endosomal localization is dependent on the interaction with TSG101. SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm, cytosol. Nucleus. Note=Translocation from the cytosol to the nucleus is seen only in the presence of MC1R and MC4R, but not TBXA2R. Excluded from nucleoli. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytosol. Nucleus. Note=Translocation from the cytosol to the nucleus is seen only in the presence of MC1R and MC4R, but not TBXA2R. Excluded from nucleoli. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm, cytosol. Cell membrane. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm, cytosol. Cell membrane.
Protein: IPYR4_ARATH
Sequence: MAPPIEVSTKSYVEKHVSLPTLNERILSSMSHRSVAAHPWHDLEIGPEAPIIFNCVVEIGKGSKVKYELDKTTGLIKVDRILYSSVVYPHNYGFIPRTLCEDSDPIDVLVIMQEPVIPGCFLRAKAIGLMPMIDQGEKDDKIIAVCADDPEYRHYNDISELPPHRMAEIRRFFEDYKKNENKEVAVNDFLPATAAYDAVQHSMDLYADYVVENLRR
What is the function of this protein?
Catalyzes the irreversible hydrolysis of pyrophosphate (PPi) to phosphate.  The MgPPi(2-) complex binds to the enzyme only after a free Mg(2+) ion has bound.  No activity with glycerol-3-phosphate, glucose-6-phosphate, p-nitrophenylphosphate, ADP, NADP(+), NAD(+),NADH, NADPH or phosphoribosyl pyrophosphate as substrates.
What are the official names of this protein?
Soluble inorganic pyrophosphatase 4, Pyrophosphate phospho-hydrolase 4, PPase 4.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_SHESH
Sequence: MPRRRVVGQRKILPDPKFNSELLAKFINVIMQDGKKSTAEKIIYKALDTASEKKSEDHLVILEAALENVRPSVEVKSRRVGGSTYQVPCEVRPVRRNALGMRWLVEAARKRGEKSMALRLAGELLDASDNKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: HEM3_PYRCJ
Sequence: MKIRVATRGSKLSLLQTQELLDQVKAVEPKVEFELVVVKTTGDVVQDRPLYQIGVKGIFEKEVNLAVLRGEADVAVHSLKDLPSELTPGLVIAGFSRRAPPYDVVASREGYSLYTLPKGAVVGTSSVRRAEFLRAVRPDVEVRPLRGNVDTRVGKILSGQYDAAIMAMAGLVRLYGWEAPVKLSPIRPEEIPPPPGQGIVVAVVKEGEAWLIDILRRASDRRAAVEATAEREFLMHVGAGCHVAVGGLARYEDGGMSFVAGYASGGRRYVIKLWGEDPREVGRRAAEEIRKIREGD
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Probable porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: F1142_HUMAN
Sequence: MSDKDDIETPLLTEAAPILEDGNCEPAKNSESVDQGAKPESKSEPVVSTRKRPETKPSSDLETSKVLPIQDNVSKDVPQTRWGYWGSWGKSILSSASATVATVGQGISNVIEKAETSLGIPGPSEISTEVKYVAGETNAKENENSSPVAGAFGVFSTISTAVQSTGKSVISGGLDALEFIGKKTMDVIAEGDPGFKRTKGLMNRNATLSQVLREAKEKEEIRTSNEVTVETDKKTHYGLLFDEFQGLSHLEALEMLSQESEIKVKSILNSLSGEELETLKVELEQLKETFSLAEFCEEEEEEKKGDEDFTKDITELFSQLHVSSKPEKLARARNTAHEWIRKSLTKPLAENEEGEKQSEAENTEQVNKNSIEDIHAFAIRSLAELTACSIELFHKTAALVLHGRKQEVTAIERSQTLSQMTIVLCKELSSLSKEFTTCLTTAGVKEMADVLNPLITAVFLEASNSASYIQDAFQLLLPVLEISLIENKIESHRHELQGQKPLLEH
What are the official names of this protein?
Protein FAM114A2.
What is the protein family that this protein belongs to?
Belongs to the FAM114 family.
Protein: GLNA3_RHILP
Sequence: MTLDLAAFARDKSIKYFMISYTDLFGGQRAKLVPAEAIADMQKDGAGFAGFATWLDLTPAHPDLFAVPDASSVIQLPWKKDVAWVAADCVMDDRPVEQAPRVVLKRLVAEAAKEGLRVKTGVEPEFFLISADGSVISDQFDTAEKPCYDQQAVMRRYDVIAEICDYMLELGWKPYQNDHEDANGQFEMNWEYDDVLKTADKHSFFKFMVKSVAEKHGLRATFMPKPFKGLTGNGCHAHISVWDVDGRVNAFADKEMAFGLSAQGKTFLGGIMKHAPALAAITNPTVNSYKRINAPRTTSGATWSPNTVTWTGNNRTHMVRVPGPGRFELRLPDGAVNPYLLQAIIIAAGLEGIRSQADPGQHYDIDMYAEGHLVKDAPRLPLNLLDALRAFDADEGLKAAIGAEFSSAYLKLKHLEWNAYCSHFTQWERDSTLDI
What is the function of this protein?
Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase III, GSIII.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
Protein: TDL1A_ORYSJ
Sequence: MRVSSASSTPPPPAFAAAAWAVVLLAMLRSDVALAAAASSNDDTGLSPLMPPPPLAAPVPAAVSPAPATPPAVLSPRKLLRPQGADVVGVGFVSGSGGGGGGDGVRTRRVDDGCAGADDIAIYQGRATPLPSGVPAYTVDVMNRCAGGGGGDEECAIAGIHVRCGWFSSVSLVDPRVFRRLGHDDCLLNDGRPLLAGETVSFEYTNSFPYKLSVSVATCVVDPAAP
What is the function of this protein?
Involved in cell specification during anther development.  Required for the differentiation of primary parietal cells into secondary parietal cells in anthers (PubMed:22913653).  May serve as an extracellular ligand for the MSP1 receptor kinase to limit sporocyte number in ovules (PubMed:18248596).
What are the official names of this protein?
TPD1 protein homolog 1A, Protein MICROSPORELESS 2, TPD1-like protein 1A, OsTDL1A.
Protein: TSAD_SORC5
Sequence: MRVLGIETSCDETAAAVVTEGGDVLSDVVRSQVALHAPYGGVVPEVAARDHARAVVPVVREALSRAGVSAADLDGIAVTSRPGLAGALLVGLQAAKGLAWAAGKPLVGVDHLVGHLLAVFLRRGGAPLSDERERPSFPYVALLASGGHTAIYRVDGPALGAIRELGATRDDAAGEAFDKVAKLLGLGYPGGPVVDRLAAGGDAAAAADAVPALMARKESLEFSFSGIKSSVARHVAKRGRPEGQALRDLCAAFQGAVVDALVQKTVRAARAEGIGRVVLGGGVAANQGLRAKMAAACERRGLALFVPPLASCTDNGAMIAYAGALRLAAGERDTLDLAPETRTALPRVTRKGGGAR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_CITBB
Sequence: MRLIIAGGGTGGHLFPGIAVADEFLARSPENEVLFVGTERGIEARLLPKLGYKLALISASGMKGMGTIKKIMSAGRLLYGYSQSRKILKEFRPDLVLGVGGYASAPIVLAARGMGIRRFIHEQNAFPGLTNKVLGRFVDGVFISMPEAESFFPKEMTQMTGNPIRKEILWGFQERVRSIGDTFSILVFGGSAGAQRVNSALLEALPHLEGVKGKLRITHQTGEKDAARVREGYQAQGFQAQVLSFIDDMSAAYGAADLVVCRAGATTIAEVTACGKGCIFIPFPYAADDHQRKNAESLVHKNAGVMILEEDLTGERLAAKILELMEHPAELAEIEKNARALAQLDAAQAIVSAMVSKN
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: WNT2B_HUMAN
Sequence: MLRPGGAEEAAQLPLRRASAPVPVPSPAAPDGSRASARLGLACLLLLLLLTLPARVDTSWWYIGALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRVMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQDGANFTAARQGYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWLDQT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt/beta-catenin signaling pathway.  Plays a redundant role in embryonic lung development.
What are the official names of this protein?
Protein Wnt-2b, Protein Wnt-13.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: TYW3_THESM
Sequence: MFLYEKNFDLQKKKALESLNDALEKGLVDSDIISLLNKINSLKNYFTTSSCSGRISIMQMPDLGDKLNAIWLGKWHREVKIEEVLDTINKHDGGMLWFMVHSPILHVSAKTLEDAVELLNLAMACGFKHSNIKSVSHKKLVVEIRSTERMDIPLGSDGELWVNESYLVKIVSMANLQLRRTKEKLRKLEDEIQKLKK
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway.  Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.
What are the official names of this protein?
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase, tRNA wyosine derivatives biosynthesis protein Taw3.
What is the protein family that this protein belongs to?
Belongs to the TYW3 family.
Protein: MURG_RHOPA
Sequence: MTDAPLILLAAGGTGGHLFPAEALGVVLIRRGYRVRLVTDHRATRYSGLFTAEMTDVVPSETVRGRTPWALAKTALKLGSGALLAFNLIGRLKPAAVVGFGGYPTLPPLLAATWRRVPTLIHEQNAVMGRANRFLAPRVDAIATGFPGHEIAWPVLASKITNTGNPIRPAVADAATVAYDPPAAGGSLRVLVFGGSQGARVMADIVPPALEKLDPALLRRLVLTQQVRDEDMGRVRAVYDRLQLNCELAPFFTDLPQRLASSQLVVSRSGAGTVAELAAIGRPGILVPLPGALDQDQFANAGVLTAAGGALRIVQPDFTPDRLAAEITALAADPAKLTQMAAAARQIGRLDAAERLADVVGRVAKV
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GATA_STRSY
Sequence: MTFNNKTIDELHDLLVKKEISAVELTKATLEDIKSREGAVDAFLTITEDAALAQAAALDEKGIDADNVMAGIPLAVKDNISTKGILTTAASKMLYNYEPIFDATSVAQAYAKDMIIVGKTNMDEFAMGGSNENSAFKPTKNAWDQTKVPGGSSGGSAAAVASGQVRLSLGSDTGGSIRQPAAFNGIVGMKPTYGTVSRFGLIAFGSSLDQIGPFSQTVKENAQLLNVISGHDVKDATSTINEIADFTSKIGQDIKGMKIALPKEYMGEGIDPQVKETILKAAKHLESLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAEDATNLDEIYVKTRSQGFGEEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFADYDLILGPTAPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGLSIPAGFVEGLPVGLQLIGPKYSEETIYQVAAAFEATTDYHKQQPVIFGGAN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.