PharMolix/UniProtQA huggingface dataset:
Protein: PRMA_SYNP6
Sequence: MPVSQSWWQVEVHCDPLLEDLLYWRLSEAGGRGFVCESKAQGLQVHSYFPAELWEETIRDRLLQEINADAADLGLPTPSLSWQTLDEEDWSESWKRHWQPQELGDRFLIQPAWLEPEPSDRLLLQLDPGTAFGTGAHPTTQLCLEGLETVPVADKVIADVGCGSGILAIGALLLGAKQVYAVDTDPLAVGATQANAALNDLEGDRFWTAIGSADQLQPLHAQGVRFDGFLCNILAHIIQALTPTLSELASPGSWAIFSGLLTSQADTVSVTLEEYGWVIRDRASQGDWCRLVADFRPER
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UFC1_ORYSJ
Sequence: MEGWDKGTKSVVGEIPLLSTRAGPRDGEAWRQRLKEEYRALIAYTSVNKSKDNDWFRISAANPEGTRWEGTCWYVHNLRRYEFPLQFDIPVAYPQVAPEIELPTLDGKTHKMYRGGKICLTVHFKPLWAKNCPRFGIAHALCLGLAPWLAAEVPILVDSGMVKHKDDEAAPADAAAAASGSAAAS
What is the function of this protein?
E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: ITM2C_PIG
Sequence: MVKISFQPAVAGIKGDKADKASASASAPAPAPAAEILLTPAREERPPHHRYKKGSSVGGVCYLSMGMVVLLMGLVFASVYIYRYFFLAQLARDNFFHCGVLYEDSLSSQARTRMELEEDVKIYLEENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFWELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTYRLRRRATRRRINKRGAKNCNAIRHFENTFVVETLICGVV
What is the function of this protein?
Negative regulator of amyloid-beta peptide production.  May inhibit the processing of APP by blocking its access to alpha- and beta-secretase.  Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor.  May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
What are the official names of this protein?
Integral membrane protein 2C.
What is the protein family that this protein belongs to?
Belongs to the ITM2 family.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass type II membrane protein. Cell membrane; Single- pass type II membrane protein.
Protein: Y3936_BACC0
Sequence: MGFPKVERLLINYKTLDEFKKFKGCGAQELSMLEELQANIIENDSESPFYGIYYGGSLIARMSLYMKRNGGEPFEITGTYLELYKLEVLPNFQKQGFGEMLVNYAKGLQFPIKTIARIHSAGFWDKLNFQPVSVPDGDFYVWHPETNLNAVTNEESA
What are the official names of this protein?
Uncharacterized N-acetyltransferase BCAH820_3936.
Protein: RNC_PHOPR
Sequence: MTSPANRLQRRLGYQFNSSELMTLSLTHRSANGKHNERLEFLGDSILSFVIADDLYHRFPHVDEGDMSRMRATLVRGKTLAELGREFELGDYLLLGPGELKSGGFRRDSILADCVEAIIGAIYLDSDTEQVRKVILSWYQSRLETIQPGINQKDPKTRLQECLQGRRLALPAYTVTKVHGEAHNQEFTVQCEVTGLDKPVIGKGSSRRKAEQAAAELALKQLES
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAHO_CAVPO
Sequence: MTATRCCLWLLLLGTCMALLLPEAWGAPLEPVYPGDDATPQQMAQYAAEMRRYINMLTRPRYGKSAEEDALGLPVWRQSHAAAPGGSHRHPPAGLPAAKGGTGVSGSPPKPWDCLPCRAHSLPSQS
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2.
What are the official names of this protein?
Pancreatic polypeptide prohormone.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL31B_METFK
Sequence: MKPGIHPEYREVVFQDIGADFSFLTRSTIAAKETIKWTDGKEYPLVKIEVSSQSHPFYTGKQKILDTAGRVEKFRQKYGM
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: GLGB_DESVV
Sequence: MTIPCSRPLFIEPFDLYLFGMGRHRHLYRILGAHPAVQDGEAGYRFAVWAPNARSVHLSGDCNGWRHEGCPLFPVGVSGVWAAFVPGVRRGSLYKFVVRGADGRQEQKADPFALWAEMRPGVASVAWDIDNHAWGDGAWMAERARQGLPLERPVSIYEVHLGSWRRRHGDGHPFLTYDELGDQLIPYATGMGFTHLELLPVAEHPLDQSWGYQTGHYYAPTSRFGSPEGFKRFVDRCHQAGLGVILDWVPAHFPRDAWSLGRFDGTALYEHLDPRLGEHPDWGTYIFNYGRNEVRNFLTANALYWLREFHIDGLRMDAVASMLYLDYSREAGQWLPNRHGGRENLDAVDFLREVNTVIHAEFPGAMTLAEESTAWPGVSRPVYTGGLGFSFKWNMGWMHDTLGYLAEDPIHRAYHHGSLTFSMLYAFSENFVLPLSHDEVVHGKGALLSKMPGDMWQQQANLRLLYAYQWAHPGKKLLFMGGEFGQWNEWDESRELDWCLYRFPAHEGIARLVGDLNRLLRSEPAMHRRDHDWSGFRWVDFADYGSSVISFLRLAEGERPLLWIFNFTPVVRRFYRVPCPRGGTWRELCNTDSAYYGGSDVGNAGAVMAREDHWGGGHFIELTLPPLAAMCFAPVTGQGT
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: NDK_METPB
Sequence: MANERTFSILKPDATRRNITGAVNAVIEAAGLRIVGQRRIRMTRAQAEKFYEVHKERPFFGELVEFMTSGPVVVQVLEGENAVAKYREVMGATNPAQAADGTIRKQFAESVGENTVHGSDSADNAKIEIAQFFTDADIAA
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BACCQ
Sequence: MFVDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFVVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGRKSEDLIVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVIVHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDLLFEVANLLETTPEFPIHEVADESDTSVMYKLETEGVKFDITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGMGIDEALRARGAKDGDIVKILEYEFEFID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YA745_GIBZE
Sequence: MAMFPPVEDSVLQNNPDFVNLYNKLTNVVLNSDCSTQNGPRAKERASVRQELDRRRLISAKQHLLTCAISSATPSSTPPATRASSRLQPPKGHQAGGSNSQQQQPSLPEPLLDLLIVLPPLLDANNPPLPQDTLQLLFAHPPLSELETLLPALAPIIASNLRTWALGLARIAHPSTNASFLHRHIASLPTTLSGWRSDLAAAETELSSHRLRSLAALTSLLQAATNALSLLIRALEVKHGKVARSLELRAAEASLHARRYDADAVIAAASVRRAFYTPEAITALRNYGAHLRDAKMRSEERVRGLAAELGEYGVGVDGGENKEKKMREMSRVYREMTRQMDDTRRDLDRLNQG
What are the official names of this protein?
Uncharacterized protein FGSG_10745.
Protein: DPO3A_ECOL6
Sequence: MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDFTNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNIGYQNLTLLISKAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEEHFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVAIHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEYFLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLDTELQVINQMGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVVGLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKGGYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAKAEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKEIERYVGGVRLKDMHPTERGKVTTAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVMLFTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISLTDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDLRGLIGSEQVELEFD
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTPBA_XENTR
Sequence: MVWCCRPLLRKYGNFIDNLRIYVKGGAGGMGLPRLGGQGGKGGDVKLVAKKEVTLKKIKDKFPHKRFIGGVGGNSSVRALKGQPGEVCQVEVPSGIVITTEHGVKIGELDKEGDEIRVARGGQGGVFQTDFLPSKGQKRIIHLDLKLISDVGLVGFPNAGKSSLLSRISHAKPQVAEYAFTTVKPELGRIMYPDYKQISVADLPGLIEGAHYNRGMGHKFLKHIERTRQLLFVVDVAGFQLSASTLYRSAFETVLLLTLELQLYKQELLDKPALLAVNKMDLPNANEKFEELLKQLENPAGNFHLLPDELVPERPIEFKHIIPVSAATGQGLENLIGCIRKTMDEQADMEIRELAQERLQSLQKETSRTVKRNLKNSPQRTHH
What is the function of this protein?
May be involved in the ribosome maturation process.
What are the official names of this protein?
GTP-binding protein 10.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Found in the dense fibrillar compartment region of the nucleolus.
Protein: ACCD_CUSGR
Sequence: MQNWIDNSFQAEFEQESYFGSLGENSTNPSSGGDRYPEALIIRDITGKTSAIYFDITDDILENDPHQTILLSPIENDIWTEKDVIIDTYRYINELIFCDEKSQQKQKDRTEFIKKEQLQLISNRNPDHYRNLWNQCENCFIPNYKKVLKSNMQICEECGSYFKMTSSDRIDLLIDEGTWNPLDQDMVSLDSSEFDSEAELECYEDNIKEWNEEMCQAFMRKLSKDLKEGQALERTANLIEEPWLPEYIQPEEKVEEWTKPDLDEGEESQDEERWIWELDKGEESQEIEDSEANDEDDDDAPYVERLAFYKKETGLLDAVQTGVGQLNGRPVALGVMDFRFLAGSMGCVVGEKITRLIEYATNNLLPLIILSASGGARVHEGSLSLMQMAKISAALYDYQSNKRLFYISILTSPTTGGVTASFAMLGDIIITEPGTFVAFAGPRVVQQILNETIPEEEQEAEALFEKGFFDLIVPRHLLKNVISELLNLHAL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid.
Protein: MED5_PHANO
Sequence: MCVPAKQGTLHAKSPLPGLKIAGLLLRPRAANASSVDPRVIIYLERLLALKKVDASDVLSSAFQYSKDRLPKTGDDGSSKDSGWHNPPELEEVVFHRLSKAFQAEERPVNSTEGLRTLVVVTRWMQTMVTSHTSDTMIQAMAGIQQQPQQQSINVREGLGMLVVGVIENQKMLNILNKHHIKNCKSPGRSRKSNTTFTTNLATGEWRSERRSRTETQDLKSLRSNFEAVDWIFPTINTRAGLYIFLNSLIDSQNMATDLITAAFDILANAMYRSEPSQNMFCLKSFLINKIPILLLQISSSMFPMTAELSITQALSHVDPNAFPAFSQGFDDMLGNTNSLADVRQDFLNACALHGLITTATVERLLGETPMQGPPGTKYDKSTLLEQCKSNFDKISMYIDELDNLDGNAGAIVGAIAEFIPHLCETQMTMYLKQLSSLLFKKPQAIDVILQFTSPASILRPLCQILDDWHYDSDQGEYQPVYDEFGAVLVLVMTFMYRYDLTYHDIGIGAESFVARLMTKGNQSMLPDEMTDEQSKHLGHWLKGLYDAGNEGLSNDVFASCSPREFYFIVPTLFKQTVMALSAGILTFESVKGGLEYLMETFLLPSLIGGLIWMSSYALIQSHSDLDAIMRIFREVISSAPSSGDAQAMHSTILSIVSSRLEKCLRTIQRRDASRANSIEPLIQAIKGNLHSERSMFASMKELEQWTNAPNSTLHTSLRHTVQQLSQWASTSSIQPNPPSYTHRQVYVSLKIMGASKVIKAIVDELKAQTEASNGAAALDVGVSIICAPTVDDSPVPVAWLSSPIPASNPPRTRLNLREMLKHEFDNAAALVATDPLAAETVVRLHRRVEAQLSSIAENALQGHGSVLNLPNVNMGDMQSQSIPDDITKAIDDAAAASIADDITTMDNKALQRSMDDLTGPDGLDLSSIGMGTGDAGTGDMGAELGNLPDLDLGDMSGMGMDMDMDMAMGGGGDDDWGLDFDNM
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 5, Mediator complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSTB2_NATPD
Sequence: MTLLSTLRGISSPARQQPGTQSESRRGGDTLAERGLAVAGVSHGFDGTAVLESVTLAVDRGETVAIIGPSGTGKTTLLRLLALFSEPDDGTIGLDGTDVWRQSERQRLAARRRIGMVFQKANLFDTTVRRNVRYGLSVRRSWRERLRSWLGGRKRQESVFEALDIVGLADAASQSASSLSGGEAQRVAFARALAYDPDFLLLDEPTSDLDPRNTAVIEEAVDAARSRGLGVAVATHDMHQARRIADRIVVLLDGQVIEAGPTERVFSDPDDARARKFINGELVY
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ENOPH_CANDC
Sequence: MASTTNNTPIDTVILDIEGTVCPITFVKDTLFPYFIEKLPSILQKFQYPLPTTTTSDNDDDDDDDPVLNILKQLPENIIQSWESIFNHFKNLVDQDIKDPILKSLQGLIWKQGYENNELKAPIYQDSIKFIESFPTVKSKDNQRKIYIYSSGSIKAQILLFGHVKNSSTSTTSSSIDNDTIDLNDKLNGYFDITTVGFKNQSNSYIKILQEINKSQYPQSVLFLSDNINEVNAAINAGMKSYIVIRPGNSPINDEDKKFHKIIYSLDELDL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CCMA_JANSC
Sequence: MVLTVTDLACARGPAQVLSGVSFSVSAGEALILRGPNGAGKTTLLRTLAGLTPPLAGTISHAEDAIAYAAHADGLKAQLTVAENLTFWATIFGTLDIAPAIAAFALAPLADRPAGELSAGQKRRLSLARLLVTGRPIWALDEPTVSLDTENTARFAAAVEAHLRAGGAAIIATHIDLGLPNARSLDITPFIAKGLPASDPFADDPFLGAAL
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CCL4_PIG
Sequence: MKLCVTVLSLLVLVAAFCSPALSAPMGSDPPTSCCFTYTVRKLPRNFVTDYYETSSLCSQPAVVFQTKKGRQVCANPSDDWVQEYMDDLELN
What is the function of this protein?
Monokine with inflammatory and chemokinetic properties.
What are the official names of this protein?
C-C motif chemokine 4, Macrophage inflammatory protein 1-beta, MIP-1-beta, Small-inducible cytokine A4.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIPF4_HUMAN
Sequence: MQPPGPPPAYAPTNGDFTFVSSADAEDLSGSIASPDVKLNLGGDFIKESTATTFLRQRGYGWLLEVEDDDPEDNKPLLEELDIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLAVVLFFSMISLYGQFRVVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPLIVIAPVLLVVGSFEVVSTLIKLFGVFWAAYSAASLLVGEEFKTKKPLLIYPIFLLYIYFLSLYTGV
What is the function of this protein?
Involved in the maintenance of the Golgi structure.
What are the official names of this protein?
Protein YIPF4, YIP1 family member 4.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
Protein: MSD2_MOUSE
Sequence: MAAPCGSELPANSPLKIPKMEVLSPASPGDLSDGNPSLSDPSTPRGASPLGPGSAAGSGAAASGGLGLGLGGRGAASSSVSFSPGGGSGGAAAAAAAACRGMSWTPAETNALIAVWGNERLVEARYQQLEGAGTVFGSKAPGPAMYERVSRALAELGYERTPSQCRERIKTLRRCYSRVKEHGVGKRKSSYTFEQLEQVFGQGGWDAQPCQPVLINSSGLYQELESDGSTMEDYSQEDWGNHSQELHGYPTDQELDEMPVSKRTLKIKQESSEEAQKRDTMQNIVQILESVQLKWELFQSWTDFSRLHLSNKLAIFGIGYNTRWKEDIRYHYAEISSQVPLGKRLREYFNSEKPEGRIIMTRVQKMNWKNVYYKFLEITISEARCLELHMEIDWIPIAHSKPTGGNVVQYLLPGGIPKSPGLYAIGYEECIERPLSPDVERHALDPGKEGRVDLETLSAQASLQVEVEPTRIIYCYLGIAEVRTLQQCLFLHFQANAKTFSKEWVGINGFLSQNCIVDPGVSPKSIYIKFVEVERDFLSAGSLVECLEKAIGYPLKFNN
What are the official names of this protein?
Myb/SANT-like DNA-binding domain-containing protein 2.
Protein: MICA2_XENTR
Sequence: MGENGDDKHGRSGQLFENFIQATTCKGTLQAFNILTRQLELDPQDHRHFYAKLKSKVTSWKAKALWNKLDKKHGQKEYKKGKACIGTKCLIIGGGPCGLRTAIELSCLGAKVVVVEKRDTFSRNNVLHLWPYTIHDLRCLGAKKFYGKFCAGAIDHISIWQLQLMLFKIALLHGIEIHVNVEFMKLLEPLEDQENQNIIALFCTESESPDNSECKTRLSAPVVFRCIVGIGGDHSFPNTLAFAFIYIYMNRNKEAVGPSPVWALAGRPRPLHTALLQPGRQQNRIDLENIVYYKDSTHYFVMTAKKQSLLDKGVIINDYADAEMLLCAENVDQDNLQSYAREAADFATNYQLPSLDFAINHYGQPDVAMFDFTSMYASENAALVRERHGHQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVRSWAQGALPLELLAERISLLIFLNHRLTWQFLNPKKGLQTCHPNVWIPSHALRLSHHVKHLFITNELQTCSLERASSIRRSVGVSRHESDVRPNKLLIWCQKQTEGYGNVTVTNLTSSWKSGLALCALIHRFRPELVDFGSLKEDDVVGNNQLAFDIAEREFGISPMTTGKEMAATEEPDKLSMVLYLSKFYELFRGAPLRPVDTASKDNGDARSAKPSNLIVNNYLNLTLPRKRVPKDEKTSDDSDLNKRRKTVFRCFEEPANVPSRNVNSGNECNDTKEVINQNKVKSMATQLLAKFEENAPNTSLRRQESLTLSEADQAVTAPLTDPPPVNPRFAKPQEPTPSPPQAETKRQFQAVSRTQPVVRPPVQPRPGPAKPTRELRVVERAQSHPDDLGRSESLSSACPSALVLSNILERLQDLEEKAQQKRAQNLANRDFHKKNIKEKAAHLASLFGSVDLPKNKLPSLGFSHHSPQIPYSSSRTPDPPPPSSSSDSSPSSAPSRKSGMSWKGSTFFSKHSLNVWILMTVGKVSSGIGAVAEVLVNLYMCDHKPKPKSSHLGSLRKEFPANIGGSDTCYFCKRRVYVVERLSAEGHFFHRECFKCAFCSTSIRLGNYVFNVEDGNFYCQPHFMHSVTKNKHRKRRTESKAQLEEDKTWRSGEAEAAEVATDSAYSACSSSGDSSPVPLVPFNIPVLDPLIG
What is the function of this protein?
Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the srf signaling.  Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (By similarity).  Acts as a key regulator of the srf signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase mkl1/mrtf-a presence in the nucleus and promote srf:mkl1/mrtf-a-dependent gene transcription (By similarity).
What are the official names of this protein?
[F-actin]-monooxygenase mical2, Molecule interacting with CasL protein 2, MICAL-2.
What is the protein family that this protein belongs to?
Belongs to the Mical family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: DPHB_METAR
Sequence: MLTFIGLGLYDQKDISVKGLEAIREADVVYAEFYTSRLMGATLEDMQELYGKPVKVLMREDVEQHPKDTVLSDAVDKKVVFLTGGDAMVATTHVDLRLRAKKMGIETRLIHGASIQSAVCGLTGLQNYRFGKSATIAFPYKDIISETPYDTILMNKKNGLHTLLFLDIDREKGYMTVNRGIELLLKVEERRKEGAVAGALCVGIARAGSPSPCVRAGRIEELQAFDFGGPLHIMVMPADLHFLEEEALQDLAGLKLG
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: RRP36_YARLI
Sequence: MKRDSNRNLVRKRADDSDSDDYNTFAGLEKDSGPEEMSSLSFGAIRNAQKNLDKENEDDSDSDSDSGPEENSGGYERSSYKGNNKGKGNNKEDGGPKKRLKHAPSEASSKKRVSVIRPIPGLTMTKSGADSASRDSKLYRDIRFDATYGKANEDRVREDYAFLDEYRREEIAELQAKLKKTEESYIRSQIQTQIQSLQSKLKTLEKRDFRKKVLNEHRQQQREQAKDGKNPYYLKRSDQRKLVLTEQFKTMKKKDIDRAIERRRKKITGKEKKDMFSGRD
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ASMT_HUMAN
Sequence: MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK
What is the function of this protein?
Does not show Acetylserotonin O-methyltransferase activity.
What are the official names of this protein?
Acetylserotonin O-methyltransferase, Hydroxyindole O-methyltransferase, HIOMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: CCNJ_XENLA
Sequence: MELEGLWWKGQLAVDIHQTLRYKELKLPSYKGQSPQLNLRRYFADLIAIVSNRFKLCPTARHLAVYLLDLFMDRYDISIQQLHIVALSCLLLASKFEDKEDRVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFEWNLCLPTPAHFIEYYLSIAVHDTDLHDGWPMICLEKTKIYMAKYADYFLEVSLQDHMFLNYGPSLVAAACVAASRIILRLSPSWPTRLHRLTVYAWDILVPCIERLLIAHDNDVKEASKHKNHLSHTAAQCLFPPASPAPPQAHVQQHMPPYLQSQHHQLQFHHSAPQPQNCQPIITAAHASAFPLQTCASAIPTSIQARGHIQTTASVSLAAVPIEVKPCIGVSYNRSYQVNGHYSRLTQCFDR
What are the official names of this protein?
Cyclin-J.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin J subfamily.
Protein: KEX1_VANPO
Sequence: MMVSYKLLSLITLLFVAQCTTGLLKQDDYVVRPDLLPGISSIKDKALIPKMYAGHIPLNLQKTTDENENTDESDSNSNTNYFFWKFQHQSVESPNLIFWLNGGPGCSSMDGALVETGPFRVDKNGKLYPNEGSWHSRGDLVYIDQPIGTGLSTSAAIPNLLDDLKEVSDNFILFLENYFTIFPNDLDKDIIIAGESYAGQYIPFFAKAIKEYNQKISDNKKKINLRMLLIGNGWIDPITQSLSYLPFAIEKNLVGKDTPDFETLLKAHEKCQNKINSISEDDNSFSHEECESIINMLVSVTKDNSPNVKSNEVCINIYDFNLRDSFPACGANWPIDVSHVAKFFSTPGVIEALNLNAEEVPRWKECNYDVLNHLTNPVSKPSVRLLPELLESGIEIILFNGENDLVCNNKGITDMISKLTWNGATGFSDKVQKYEWLFRDLTKDTEEPAGTVTFDRNLTFISVYNASHMVAYDKSIVARGILDIYLDNVMLVEKETDSPDVLISTNEPTFSDIEEEELDGEKEDEKDGVTEGDGEKSDTDEGKDTDKGKDEKNDDDDDDDDDSDDDSDDDDDDDDDDDDDDDDDDDSDDDDDDDDDSDDNEKDDKSESETKTHPKAKIALLLLLFISVFGITGSQALRQRNFQFRRAPLTSNSFSSSSSPNDPSNWDSNDDFDFDIENDPLPSTNNKHKAAKKKKDYVSIPSDIDESFELAEI
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.