PharMolix/UniProtQA huggingface dataset:
Protein: CAV1_GORGO
Sequence: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation.  Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity).  Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).  Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.  Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity).  Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity).  Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Caveolin-1.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: CAS2A_THET2
Sequence: MRELYLVIAYDTPDDRRRARLAKLLKGFGERRQYSVFEARLTREQWAHLKGKLEALVNKEEDVLAVYFLPPEAVGRTWRIGHEGLKRLEDPDFV
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: SYC_AZOPC
Sequence: MKNQLFIYNTLTGRKELFQSLYPKRVGLYVCGPTVYGDPHLGHARPAITFDILFRYLMHLNYKVRYVRNITDVGHLTSDSDLGEDKIARKARLEDLEPMEVVQHYLNLYHKTMDALNVLPPSIEPHASAHIIEQIQLIKEILEKGYAYESKGSVYFDVEKYNKKYNYGKLSGQNIADMLNTTRKLDGQEGKRNPIDFALWKKASSKHIMQWISPWSNGFPGWHLECTTMSRKYLGNLFDIHGGGMDLIFPHHECEIAQKVASTGYEGVKYWMHNNMVTVNGQKMGKSSNNFINLEQLFNGTNPLLIQSYNPMTVRFFILQSHYRNTIDFSNKALQASKKGLSRLLEANNNIKQLTAQTTNSTVNIEGLRNKSIEAMNDDLNTPIIISYLFEATRIVNSALAKQTQLTTEDIQQLKDFFQLFLFNLLGIKDELKYKNTSYNSFAKAVDLLLQIRVQAKQEKNWIFADKIRDELTVLGFEVKDTKNGFEWKLSK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_CHLPB
Sequence: MRNLAVFGTASDVGKSVVATALCRIFSNAGLDVAPFKAQNMSNNSGVTPDGLEMGRAQIVQAEAARVVPTADMNPVLLKPNTDTGAQVVLQGKAVANRSARDYFGNTEVWAEAAFESLERLTGRHDLVVIEGAGSCAEMNLYDRDFVNFRTAKEADAPVILVADIDRGGVFAQVAGTLSVIPPEDRARVKGVIINRFRGDSVLFDDGIRILEELSGVPVLGVIPYFRGIHIEAEDAVPLQAVVDPAASPDPGKISIAIVYFPHISNFTDFAVFDLLDDAEVHYLHHPKDLADYDAVILPGSKNVRGDLDWMIFMGWKERLAEYRKRGGIIAGICGGYQMLGISVADPHGLEGEPGETSGLGLLPVHTLLKKEKQLFNAKGCLFDDTIPVEGYEIHMGETRLTGKASPLLQLTARNNRHSSDTDGVISHDEKVFGTYFHGIFDGSAFRGWFLGKLRPDSAVNDTITEKDTEYNRLAEHFLSHLNMGKVYEIIGRGK
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: DDL_DESPS
Sequence: MQEQRAERLRIALIAGGTSGEREVSLTGADGVERILDKEKYLVSRYDSATDLPRLAADAASIDFAFILLHGLHGEDGTIQGFLDLLGIPYQGSGVLGSALAMDKDLAKEFYYNAELPVADWHTIAAGDFFYSEELIEDLGLPLVVKPACAGSSIGISLAHTEEELLAGINHARDCSAGAIMVEQFIKGRELTCAVLGNDDLQALPVLEIVPGDKYAFFDYEAKYQPGASEEICPALIADALREQVQDHAIRAHQALRLRGYSRTDFIYGEDGKLYLLETNTIPGMTETSILPQEAAATGMDFPSLLDTLIELGLEKSKGKKG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_I01A1
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGNTLGLDIETATRAGKQIVERILEEESDEALKMPASRYLTDMTLEEMSRGWFMLMPKQKVAGSLCIKMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGALIGGLEWNDNTVRVSETLQRFAWRSSDEDGRPPLPPNQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: LEGB6_VICFA
Sequence: GIPYWTYNNGDEPLVAISLLDTSNIANQLDSTPRVFYLGGNPEVEFPETQEEQQERHQQKHSLPVGRRGGQHQQEEDGNSVLSGFSSEFLAQTFNTEEDTAKRLRSPRDKRNQIVRVEGGLRIINPEGQQEEEEEEEEEKQRSEQGRNGLEETICSLKIRENIAQPARADLYNPRAGSISTANSLTLPILRYLRLSAEYVRLYRNGIYAPHWNINANSLLYVIRGEGRVRIVNSQGNAVFDNKVRKGQLVVVPQNFVVAEQAGEEEGLEYLVFKTNDRAAVSHVQQVFRATPADVLANAFGLRQRQVTELKLSGNRGPLVHPQSQSQSN
What is the function of this protein?
This protein found in the seeds of many leguminous and non-leguminous plants is the source of sulfur-containing amino acids in seed meals.
What are the official names of this protein?
Legumin type B.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: CAS2_MYXXD
Sequence: MAEPRRWYLITYDIRDPKRWRKVHALLKGYGEWLQLSVFRCSLTDRDREKLRWELSRRMDAVDTLLVIGLCGGCVERVRAINAKEDWPEEPAPFKVL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: RPOC2_SYNP6
Sequence: MAETKSAPIFRNRVIDKKQLKKLIGWTFAHYGTAKTAVVADDLKALGFRYATRAGVSISIDDLKVPGSKAELLESAEKRIQETEDRYTRGEITEVERFQKVIDTWANTNDELTDRVVKNFRESDPLNSVYMMAFSGARGNISQVRQLVGMRGLMANPQGEIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGYLTRRLVDVSQDVIIHEVDCGTSRGLFVEAMTDGDRILIPISQRLLGRVTAEAVLDPSTDEVLAEAGQDINEDLANRIEKAGIKKVKVRSPLTCEAARSVCQKCYGWSLAHAQMVDMGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGETARLLRAPVAGTIKLGKKARTRPYRTRHGEEALLAEANFDLVLEGKGRKETFAILQGSTIFVQDGDKVAAEAILAEVPVSGRTKRTVEKATKDVATDLAGEIRFQDIVPEEKTDRQGNTTRIAQRGGLLWVLAGDVYNLLPGAEPTVKNGDRVEVGDVLAETKLTTERGGTVRMGEDNGSSTHREVEIITASVVLDTATVKAEASQGREHYVIETKGGQRFNLLAAPGTKVTTGHVVAELIDSRYRTQTGGLLKYSGVEISKKGRAKAKQGYEVTKGGTLLWIPEETHEVNKDISLLNVEDGQLVEAGTEVVKDIFCQTTGIVSVTQNNDILREIVIKPGDVHVLDDPDTAAKYDEGRLVNAGEEVFPGLTAEQLVWAEAVDGTDGPLLLLRPVQELVIPDEPPVPSQDSSQESSSRSIRLRAVQRLQFQDGERIKSVEGVDLLRTQLVLESEEGSSQLSADIELLPDSKDPETLRLQLVIIEPVVTRRDVASDTTHGSTHTELRVKDGQKVKPGAVIACTQIQCKEAGVVRGIQEGSEAVRRLLVERERDCVTLDLDVTAATQLQPGSLIVAGTQLVDGIIAPESGEARAIAPGQLQLRIARPYRVSQGAVLHVEDKGLVQRGDNLVLLVFERAKTGDIIQGLPRIEELLEARKPKEACILARRPGVAHINYSDDDAIDIQVIEADGTQADYPVGPGQPLIISDGETVDAGQALTDGPANPHDLLEIYYDYFREQLGEDYEAALESLRRVQALLVNEVQSVYQSQGIDISDKHIEVIVRQMTSKVRIDDGGDTIMLPGELHELREVYNSNNTMALTGMAPAQFTPVLLGITKASLNTNSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFKAYEESLLTDVDGGYEDRVYDDDLADVVIDDRAARSYTLNEGRDFSRSMTFAEGESMILDDGEELIDDSSASLRNLVDVDED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: MCP_FRG3G
Sequence: MSSVTGSGITSGFIDLATYDNLERAMYGGSDATTYFVKEHYPVGWFTKLPSLAAKMSGNPAFGQQFSVGVPRSGDYILNAWLVLKTPEVELLAANQLGDNGTIRWTKNPMHNIVESVTLSFNDISAQSFNTAYLDAWSEYTMPEAKRTGYYNMIGNTSDLINPAPATGQDGARVLPAKNLVLPLPFFFSRDSGLALPVVSLPYNEIRITVKLRAIHDLLILQHNTTGAISPIVASDLAGGLPDTVEANVYMTVALITGDERQAMSSTVRDMVVEQVQAAPVHMVNPRNATTFHTDMRFSHAVKALMFMVQNVTHPSVGSNYTCVTPVVGVGNTVLEPALAVDPVKSASLVYENTTRLPDMGVEYYSLVEPWYYATSIPVSTGHHLYSYALSLQDPHPSGSTNYGRLTNASLNVTLSAEATTAAAGGGGNNSGYTTAQKYALIVLAINHNIIRIMNGSMGFPIL
What is the function of this protein?
Major capsid protein that self assembles to form a T=133 or T=147 icosahedral capsid.
What are the official names of this protein?
Major capsid protein, MCP, P50.
What is the protein family that this protein belongs to?
Belongs to the NCLDV major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: HMP_VIBCH
Sequence: MLTQEHINIIKSTIPLLESAGPALTQHFYQRMFSHNPELKHIFNMTHQKTGRQSVALFEAIAAYAKHIDNLAALTSAVERIAHKHTSFNIQPEHYQIVGHHLLETLRELAPDAFTQPVEEAWTAAYFFLAQVFIDREGALYLERKQALGGWRDGRTFVVREKQVESAYVTSFVLVPADGGAVLDYQPGQYIGIEVTPEGSDYREIRQYSLSHASNGREYRISVKREGVGSDNPGLVSHYLHNNVKVGDSVKLYAPAGDFFYVERERPVVLISAGVGATPMQAILHTLAKQNKSGVTYLYACNSAKEHTFAQETAQLIAQQGWMQQVWYRDESADDVLQGEMQLAELILPIEDGDFYLCGPIGFMQYVVKQLLALGVDKARIHYEVFGPHAQLAA
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress (By similarity).
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: GRAR_STAES
Sequence: MQILLVEDDNTLFQELKKELEQWDFNVVGVEDFSHVMETFETFNPEIVILDVQLPKYDGFYWCRKMRQQSNVPILFLSSRDNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFGVEEKRTLSWQDATVDLSKDSIQKDDKTIFLSKTEMIILEMLINKRNQIVTRDTLITALWDDEAFVSDNTLTVNVNRLRKKLSEIDMDSAIETKVGKGYLAHE
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).
What are the official names of this protein?
Response regulator protein GraR, Glycopeptide resistance-associated protein R.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_PSEU2
Sequence: MNDQRKGSDAEPTTHFGYKNVPESQKAEKVAEVFHSVAAKYDLMNDLLSGGMHRLWKRFAIELSGVRTGNRVLDIAGGTGDLTRKFSNLVGPTGQVVLADINASMLKVGRDRLLDLGVSGNVEFVQADAEKLPFPDNHFDCVTIAFGLRNVTHKEDALRSMLRVLKPGGRLLVLEFSKPTNKLMSKAYDAYSFAFMPLMGKLVTNDSESYRYLAESIRMHPNQETLKSMMVEAGFDRVTYHNMTAGVVALHRGIKP
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: AK10B_ARATH
Sequence: MTIAAAPARQTDRSATGFNPAYVTTAKAVSVPVQVPPATVVSEGLGKDALISWFRGEFAAANAIIDAMCSHLRIAEEAVSGSEYEAVFAAIHRRRLNWIPVLQMQKYHSIAEVAIELQKVAAKKAEDLKQKKTEEEAEEDLKEVVATEEEEVKKECFNGEKVTENDVNGDVEDVEDDSPTSDITDSGSHQDVHQTVVADTAHQIICHSHEDCDARSCEIKPIKGFQAKEQVKGHTVNVVKGLKLYEELLKEDEISKLLDFVAELREAGINGKLAGESFILFNKQIKGNKRELIQLGVPIFGHVKADENSNDTNNSVNIEPIPPLLESVIDHFVTWRLIPEYKRPNGCVINFFEEGEYSQPFLKPPHLEQPISTLVLSESTMAYGRILSSDNEGNFRGPLTLSLKQGSLLVMRGNSADMARHVMCPSQNKRVSITFFRIRPDTYHNHSQPNSPRNDGVMTMWQPYQMTPTPFLNGYDHSIDMMPKLGVLRPPMVMMAPPPVQPMILPSPNVMGTGGGTGVFLPWASVNSSRKHVKHLPPRAQKKRLLPLPPAASSSPAGGSTSEPVITVG
What is the function of this protein?
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:29180595).  ALKBH10B-mediated mRNA m6A demethylation stabilizes the mRNA of the key flowering time regulators FT, SPL3 and SPL9, which are involved in the control of floral transition (PubMed:29180595).
What are the official names of this protein?
RNA demethylase ALKBH10B, Alkylated DNA repair protein alkB homolog 10B, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 10B.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
Protein: YL775_MIMIV
Sequence: MSGKAIFVVIIAIVLLLLIGSLIGFYFYERRRRQNAPVSPVSPVTPVQPGPPVSPTTCPAYYTIDSSDISGFNMSTINNLATQDDCSQECSKNPNCSWYNYDPNNKVCYLKKTVATPNTTTTFRIRNTGNYDKCTQWAPSINGDIPGFDIKDINNNTEDECKQECIQYDCDWYNYNSDSKACYIKKTQKQNGIVTSFRTGSNS
What are the official names of this protein?
Putative PAN domain-containing protein L775.
Protein: QUEF_CHLPB
Sequence: MQKELLEVFDNRFPDRDYTIEIVNPEFTSVCPITGLPDFGTITIRYIPDKVCVELKSLKYYYLEFRNAGIFYENVTNTILDHLVDLLKPRTLTVTTAWKARGGITETVTVSYSAGQDE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATIN_DROME
Sequence: MPKEKSKHRHRSRSRERRDHRSPDPRSSRNRDRDREREREKDRDHRDHRDKERDQRREREKDKSRDKKREHKSRRRRSSSSSSSPSSSTSSSVPGAPRSPLVKSPMKLLQTLEARRLVEQKDRQRKKEELKAHETPEEKRARRLREKQAKEQRRRERMGWDNEYQTYSNEDNPFGDSNLTSTFHWGKKLEVEGLSNLSTKTVEVLSLQKQLENRRELEKVKKRRQERELERQVREDDLMMQQRAKEAVQFREWQRQEDQFHLEQARLRSEIRIRDGRAKPIDLLAQYVAAGNEPLEECLEMQMHEPYVLLNGLPVEELEDLLVDIKVYEELEQGKHIDFWNDMITIVQDELQRQQKLEAENSSLNQRRDGIHQAVVKDVADIFRGKNAQQLEEMRHRIEAKISGRADGVDISYWESLLSQLKAHMARARLRDRHQALLREKLSLLKRENDNETLQEKVAPQVKEEEMETQDAEDPEVEEGSPEDEEDPLNELRKTVRLYQAGNYSPRYIREEDFTGRRAQNEDVDEPEAEGLLYEEEDDERRTQRQRLLILHPERVDNNQLTPQELRMRNEAKQGMQGDEAEFSVETTLDAVPQLATDKYRPRKPRYFNRVHTGFEWNKYNQTHYDMDNPPPKIVQGYKFNIFYPDLMDKSQTPQYFLTPCADNGDFAVLRFHTGPPYEDIAFKIVNREWEFSYKRGFRCQFHNNIFQLWFHFKRYRYRR
What is the function of this protein?
Plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (By similarity).  Plays a role during early embryonic development (PubMed:10842059).  Involved in the dorsal-ventral embryonic patterning (PubMed:10842059).  Probably acts as a negative regulator of the NF-kappa-B (Rel) signaling pathway (PubMed:10842059).
What are the official names of this protein?
Splicing factor Cactin, Cactus-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the CACTIN family.
Protein: MDTD_YERPA
Sequence: MVTQATSVRWQLWIVAFGFFMQTLDTTIVNTALPSIAASLGENPLRMQSVIVSYVLTVAVMLPASGWLADRIGVKWVFFSAIILFTFGSLMCAQSATLNELILSRVLQGVGGAMMVPVGRLTVMKIVPREQYMAAMAFVTLPGQIGPLVGPALGGFLVEFASWHWIFLINLPVGVIGALATLLLMPNHKMSTRRFDISGFIMLAIGMATLTLALDGHTGLGLSPLAIAGLILCGVIALGSYWWHALGNRFALFSLHLFKNKIYTLGLVGSMSARIGSGMLPFMTPIFLQIGLGFSPFHAGLMMIPMIIGSMGMKRIIVQVVNRFGYRRVLVNATLLLAVVSLSLPLVAIMGWTLLMPVVLFFQGMLNALRFSTMNTLTLKTLPDRLASSGNSLLSMAMQLSMSIGVSTAGILLGTFAHHQVATNTPATHSAFLYSYLCMAIIIALPALIFNRVPPDTGANRHLAR
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METE_BURMS
Sequence: MTTAHILGFPRIGAQRELKFALERYWRDGASADAERALVDTGRALRAEHWRIERDAGLDCVTVGDFAWYDHVLTTLAHVGGLPRRFGFDARALTLADYFAAARGNAAQPAMEMTKWFDTNYHYLVPEYSPATTFGPGVEWLFDEVREARALGYRAKAALVGPLTLLWLGKARDGLVERLALLPRLVPAYRALLARLREAGVDWVQIDEPIFSLDLPDAWRDAARPTYEALAPGAPKLLVATYFDDASEHAALLKALPVAGLHVDLVRADAQLDAFVADYPADKVLSCGIVDGRNVWRNDLDRSLARLAPVRDALGERLWVATSCSLLHVPVDLAHEPRLDEELKTWLAFAAQKTREVAALRDALVKGRAAVAAEFDDAAVVAAARRTSARIHNPLVKRRVAALTDADARRASAYSVRAAAQRARFGLPLLPTTTIGSFPQTPEIRRARAAFKQGVLDHLGYLEAMREQVRIAIDKQLAYGLDVLVHGEAERNDMVEYFGELLWGFAITSNGWVQSYGSRCVKPPLVYGDVYLPEPMTVGWASYAQSLSAKPVKGMLTGPVTMLQWSFVRDDQPRATTALQIALALRQETLDLEKAGIGMIQIDEPALREGLPLKARERAAYLDWAVRAFGIAASGVADDTQIHTHMCYSEFGDILPSIAALDADVISIETTRSNMELLDAFETFDYPNEIGPGVYDIHSPRVPDADEIERLILLALERIPAQRLWVNPDCGLKTREWRQVDAALAAMVDAAKRVRQKVEEAAPA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: PSAK_SYNPW
Sequence: MFLSLLAITPASVSWTPKVALVMIICNVIAIAIGKATIKYPNEGAKMPSASFFGGMSHGAMLGCTSFGHLLGMGAILGLSTRGVF
What are the official names of this protein?
Photosystem I reaction center subunit PsaK, Photosystem I subunit X.
What is the protein family that this protein belongs to?
Belongs to the PsaG/PsaK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PELO_METBF
Sequence: MRVTNRSLKGREGEIAVTAETLDDLWHLKYIIEKGDLVFSVTKRKADSASDKIRPEKVEKVKVRLGIRVDDLEFHKFANRLRLHGMIERGMDVGSYHTLNIEIGTNLSVIKEHWKNDQLQRIKDAEEASKRPKVVMVAIEEGDADIGFVHHYGIEIYSHIRQSSGKRETGLRNEFFREVVEQLRHAVPEEASIVIAGPGFTKEDFIKYFQETEPAMASKALIEDTSMIGMSGFQEVLRRGAVDRIMQESRIARESALMEDLIREISMDGKAAYGLGDVKNALNFGAVETLLVADETLREGREKGEDIDKLLREVEQAQGKVVVFSTAFEPGEKLHKLGGIAALLRFKVRG
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOPE_SALET
Sequence: MTKITLSPQNFRIQKQETTLLKEKSTEKNSLAKSILAVKNHFIELRSKLSERFISHKNTESSATHFHRGSASEGRAVLTNKVVKDFMLQTLNDIDIRGSASKDPAYASQTREAILSAVYSKNKDQCCNLLISKGINIAPFLQEIGEAAKNAGLPGTTKNDVFTPSGAGANPFITPLISSANSKYPRMFINQHQQASFKIYAEKIIMTEVAPLFNECAMPTPQQFQLILENIANKYIQYTP
What is the function of this protein?
Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF).  This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells (By similarity).
What are the official names of this protein?
Guanine nucleotide exchange factor SopE, Effector protein SopE, Toxin SopE.
What is the protein family that this protein belongs to?
Belongs to the GEF (guanine exchange factor) SopE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS).
Protein: SYY2_VIBVU
Sequence: MASIEAALAEIKRGVEELIPEEELIAKLKEGRPLRIKLGADPTAPDIHLGHTVILNKLRAFQDLGHDVTFLIGDFTGMVGDPTGKNSTRPPLTREDVLRNAETYKQQVFKILDPAKTKIQFNSEWLSELGAEGMIRLAANQTVARMLERDDFKKRYAGGQPIAIHEFMYPLLQGYDSVAMETDVELGGTDQKFNLLMGRELQKANGQKPQVVLMMPLLVGLDGEKKMSKSANNYIGVSEAPSEMFGKIMSISDDLMWSYYELLSFRPLEELAQFKADVAAGKNPRDIKVLLAKEIIARFHSEADADAAEQEFVNRFAKNQIPDEMPEFTFAAGTPMANLLKEAELCSSTSEAMRMVKQGAAKMDGEKVEDAKAEPAVGTYVFQVGKRKFARITIA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase 2, Tyrosyl-tRNA synthetase 2, TyrRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_BACFN
Sequence: MGRLKKLKKIRIHREGTHILWGSFFLLLIINLALYWGIDCKIPFYLVALVSIVVYLLMVNFFRCPIRLFGQDTEKIVVAPADGKIVVIEEVDEHEYFHDRRIMVSIFMSILNVHANWYPVDGVVKKVTHDNGKFMKAWLPKASTENERSMIVIETPEGVEVMARQIAGAMARRIVTYAEPGEECYIDEHLGFIKFGSRVDVYLPLGTEICVSMGQLTTGNQTVIAKLK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RR4_BABST
Sequence: RFKKIRRLGALPGLTSKRPRSGSDLKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQILLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKNKQRSKALIQNFIASSPHQEELPNHLTIDPFQYKGLVNKIIDSKWIGLKIN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRF_STRP7
Sequence: MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAGPEIVSYLKALGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNIHAAGGVEMMKAAREGLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEVQVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPVAAYHAIKDEWTQDWN
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.