PharMolix/UniProtQA huggingface dataset:
Protein: SYN_STRA5
Sequence: MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSAFFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITDLEVIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYSTYEFFDQNGFIKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVEALKRYIAEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPTFVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDDYDALVAKMDELGMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIKP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBG_ENTH1
Sequence: MPREIITLNVGQCGNQLGSEFFKKICSEHGILPDGSLSTNEFIDDRKDVFFYQADDQRYVPRSINIDLEPRVLDSIRTSEWSNFYNPENFIIPTNNGAGNSWANGYYTTEKMSEIEEIIDREVEHCDSLEGFFFCHSICGGTGSGLGSKIMEMISEKYPKNILTSFSVMVKENPDVVVSPYNSILTLRRLITECQSVVVFDNSALADITHTQFGVDEATVFDMNSIISSSMSAFTANLRFPSTLYNSLNSLMIHLCPSRFSHFLMTSYTPLRQVNQISSRTSAIDVMKRLIQPQNIMARTRLKEGKYISMCDFFQGDVSYDEINEALQRFTDRRLAEFVPWNKEAIKVVHTRVSPLVKRGNRMSGMLLANNTSIRYYFQDILKAFDQMFKKRVYLESYREQFHDNFQEFEESKEIVKCVIEEYAKAESIEYSDYSYPIHKYLKGIAKEKIAE
What is the function of this protein?
Tubulin is the major constituent of microtubules (Probable).  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly (PubMed:15500912).
What are the official names of this protein?
Tubulin gamma chain, Gamma-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
Protein: RHBL4_RAT
Sequence: MQRRTRGIDTGLLLLLSQVFHIGINNIPPVTLATLAVNVWFFLNPWKPLYHSCISVEKCYQQNDWQRLLLSPVHHGDDWHLYFNMVSMLWKGVKLEKRLGSRWFAYIIATFSLLTGVVYLLLQFASAELMNQPDFKRNCAVGFSGVLFALKVLSNHYCPGGFVNILGFPVPNRFACWAELAAIHFCTPGTSFAGHLAGILVGLMYTQGPLKKIMDACAGIFISNAGSSGQQYHFNNAGPSGYQNRYTDGRPVNYEATYRNYDIYTAGLSEEEQLERALRASIWDRGNTRNGPIPYGFRLPPEEEMRRQRLHRFDGQ
What is the function of this protein?
Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions.  Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.  Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins.  Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins.  Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner.  Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing.  Involved in the regulation of exosomal secretion; inhibits the TSAP6-mediated secretion pathway.  Involved in the regulation of apoptosis; modulates BIK-mediated apoptotic activity.  Also plays a role in the regulation of spermatogenesis; inhibits apoptotic activity in spermatogonia (By similarity).
What are the official names of this protein?
Rhomboid-related protein 4, RRP4, Rhomboid domain-containing protein 1, rRHBDD1, Rhomboid-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein.
Protein: WHIA_STRGC
Sequence: MSFTVKVKEELLGLGTKSKSELAAIMKMSGSLGIASQGLTLSITTENAKIARHIYELLLSFYQVKSDIRHHQKTNLRKNRVYTVFLDEKVEDILSDLHLADAFFGIQEGIDPLILSDDEASRAYLRGAFLSNGSMRDPESGKYQLEIVSVYLDHAQGLASLMQRFLLDAKTIERKKGAVTYLQRAEDIMDFLIVVGAMEAMAEFEAVKILRETRNDLNRANNAETANIARTVTASMKTINNIVKIMETSGLENLPIDLQEVAHLRVNHPDYSIQQLADSLSKPLTKSGVNHRLRKINKIADEL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: GPDA_CUPMC
Sequence: MKLTILGAGAWGTALASHAATAAADHDVVLWGRDPAQLAGIAATGVNATYLPGVSLSPRLVCEPDFDRAVDHALTDPEGLLIIGTPVSGLREMTRRLAARRKGPLAMLWLCKGFEAETHAMPHQMVHDELNALGVAPGEIEYGVLTGPSFAKEVAQGLPCALTVAGTAHVLIDRAQAAFHHHAMRIYGSDDLIGVEVGGAVKNVLAIATGASDGLGLGLNARAALITRGLAEMTRLGLALGGRVETFMGLAGMGDLILTATGDLSRNRKVGQQLAGGKTLDQILADLGHVAEGVRCAQAVAALAARVGVEMPITRAVCAVLFEGLPVADAVSQLLQRDARDE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAN3_CRYNJ
Sequence: MLPPPKSAAVQIVRPPSPSSEKAKEKEKKHSPEKRETAQRICRNVMIYGYCKYQDQGCIYYHPPAGADPSTPQNSSPVAHAPTPSAPTPLAGTPAREKPTLSIEHLAAPVFVPKGLDSSPRASTPSVPTPSAPTPPVWPSLPSTGLLPRQDVQVSAQPSHAQLSATASPMAYDDPSHIALSAAHAHAQAQALTHGILDPHAHAPPVDQSMYLPPRQPLDYNLYAAPLPSIGGNPLYPTHPHAFFVSDDLRRAIQAKQEAVYAGANGASAPGLPQELGVYHSLIPLPLPAPTAQCPPTQSQPSKVYGLPSPVYRATSEVDGNTYCLRRVEGFKLVNQLAFASMDTWRRMRHPNIVGLKEAFTTKTFGDNSLIMVYDYHPLSTTLYDEYLSPNPPEPSPASALANQPPKRRSSPPERILWSYVTQIANALKAIHSSGLAVRNLDASKILLTGKNRIRLNGCGVWDVLAFDNKTPVQAFQQEDLLSFGKLIISLTCDFFQPTLPFSLPLEHISRHYSSDLSNLILYLISKPAQGQIKSIDEVVKMMGPRILNELDAVQSYADVLENELGAEVENGRIVRLLTKLGFINERAEFELDPRWSDTGDRYILKLFRDYVFHSVGVDGKPILDLSHVLVCLNKLDAGLDERVMLVSRDDQSCLVVSYREIKHCIEAAFNELKNAGNNHRVHR
What is the function of this protein?
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.  PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex subunit PAN3, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. PAN3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK2_ADICA
Sequence: MVMRSYRDYTPNARKQDIPEEGRHKPCKKLTRGKISGNGRNNRGVITSRHRGGAHKRLYREIDFRRNKLDIVGRVGSVEYDPNRNAFICLINYVDGDKRYILHPKGMGIGDIVLSSPNASISAGNALPLTKMPLGTIIHNIELKSGRGAQLVRSAGTVAKVIAKEGRLATLRLPSGEIRLVPRDCLASVGRVGNVDISNKGLKKAGSKRWLGRRPKVRGSAMNPVDHPHGGGEGRTSIGRKKPLTPWGRVTLGKRSRGKKCINPLILRRRKSS
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: REPA_RHIRD
Sequence: MFQQIGAVQAKSGTDEPAHPCEKFPPERKCEAVFWKPLPRHEAREILLAARKYELAMKQPGKRTGPLGHVALEVLDYLTNLVDFGNGRLDPSISTIMEKIGRAESCMSALYPNRQRGRRPAGAADKQRLPLEPAGARPRALLGKYVRKAAPLPDDAAQARQERHDTIKAHMDSLSPADRLRETVEDRTRAEQLAGYVERAAQNRPSGPRKAARRRQQSRCSFTTPNRPRRTLPSSHPQKFGGTKGRKAFE
What is the function of this protein?
Required for replication.  It likely regulates pTAR copy number.
What are the official names of this protein?
Replicating protein.
Protein: CNM67_YEAST
Sequence: MTDFDLMNFPFHERLDSPVSENGEIKDGEPIPQNWLNENHVGKSILPLFVNPEDVINCNFSNARDSYEENKSPSMDQMNYARNTSYQESPGLQERPKNEKDKSPIGTDVHKKDVPNFIHSTPRENSSKHFTRANEQASAQPTDEHTSPDISIEDCNGAKIFLQNSLSKEDFRMLENVILGYQKKVIELGRDNLRQEERANSLQKELEAATKSNDKTLDNKKKIEEQTVLIENLTKDLSLNKEMLEKANDTIQTKHTALLSLTDSLRKAELFEIPIGILFFDLYDSEENSSKLDHILQEKYPNIKGFLCASQQEELSRISQRFKNAKAEAEDLRNELENKKIEIQTMREKNNTLIGTNKTLSKQNKILCDKFDKLTIDEKEILKGCNEEIKIKLERLNERLGSWEKSKEKYETSLKDKEKMLADAEKKTNTLSKELDNLRSRFGNLEGNTSERITIKNILQSRPDISAEECNFLMVEQIDSANLTTLQNTVKEIVLAVGIPYPKLRRKIPLLAIKLKYENIMLSNFAQRLHRQVYSQEMNLKKFTDQAYYDFMSTRRMDSIDHHLERCLDHLYDHILEKMVK
What is the function of this protein?
Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation.  Required for the proper formation of the spindle pole body (SPB) outer plaque.  May connect the outer plaque to the central plaque embedded in the nuclear envelope.
What are the official names of this protein?
Chaotic nuclear migration protein 67.
Protein: 285L_IIV6
Sequence: MDNKCTFSRKEDGVCEYKKNEVRTSQSEVPKTSIKKSDNGEKDEKEEKELNLENIIKKASANPQQRKNQKKYHRASSDCDSSDDEKDEPYYHGSKASTTLTREQALKLSLRKKIDERKLNK
What are the official names of this protein?
Uncharacterized protein 285L.
Protein: METK_THET8
Sequence: MRALRLVTSESVTEGHPDKLADRISDAILDALIAQDKKARVAAETLVTTGLVFVAGEITTEGYVDIPNLVRKTVREVGYTRAKYGFDADTCAVLTAIDEQSPDIAGGVNLSYEWRVLKSTDPLDRVGAGDQGLMFGYATDETPELMPLPITLAHRLTMRLAEVRKTGLLPYLRPDGKAQVTVVYEGDKPLYVKTVVVSAQHSPEVEQEQLREDLIREVVRQAIPPEYLKDGETEYLINPSGRFILGGPHADTGLTGRKIIVDTYGGAVPHGGGAFSGKDPTKVDRSASYYARYMAKNIVAAGLARRALVELAYAIGKARPVSLRVETFGTGVLPDEKLTEIAKKVFDPRPLAIIEELDLLRPIYTPTSAYGHFGRPGFPWEETDRVEALRREAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_CHESB
Sequence: MSRTMIKNDLKQTDFTEAGEPFRLFAEWLRDAEQSEPNDPNATALATVDPEGMPNVRMVLLKGFDEQGFVFYTNFESAKGQEILSSMKAAMCFHWKSLRRQVRVRGPVEKVTDEEANAYYASRPRGSRIGAWASKQSRPLEGRFALEKAVAEYTAKYAVGEIPRPDYWSGFRIKPVSIEFWHDRPFRLHDRILFERESGGLWTKTRLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: LAC1_PHLRA
Sequence: MHTFLRSTALVVAGLSARALASIGPVTDFHIVNAAVSPDGFSRQAVLAEGVFPGPLIAGNKGDNFQINVIDELTNATMLKTTTIHWHGFFQHGTNWADGPAFINQCPIASGDSFLYNFQVPDQAGTFWYHSHLSTQYCDGLRGPFVVYDPADPYLDQYDVDDDSTVITLADWYHTAARLGSPFPAADTTLINGLGRCGEAGCPVSDLAVISVTKGKRYRFRLVSISCDSFFTFSIDGHSLNVIEVDATNHQPLTVDELTIYAGQRYSFILTADQDVDNYWIRANPGIGITTGFAGGINSAILRYDGADVVEPTTTQATSPVVLSESNLAPLTNAAAPGLPEVGGVDLALNFNLTFDGPSLKFQINGVTFVPPTVPVLLQILSGAQSAADLLPSGSVYALPSNATIELSLPAGALGGPHPFHLHGHTFSVVRPAGSTTYNYVNPVQRDVVSIGNTGDNVTIRFDTNNPGPWFLHCHIDWHLEAGFAVVFAEDIPDVASINPVPQDWSNLCPIYNALDASDH
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase, Benzenediol:oxygen oxidoreductase, Diphenol oxidase, Ligninolytic phenoloxidase, Urishiol oxidase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQGF_BRUMB
Sequence: MATAEIEEIPALLKPGQTVAGLDLGTKTIGLAVSDLGLSFAHPRPVIKRVKFTIDAQVLLKALETDKVGVIVIGLPMNMDGTAGPRVQATRAFVRTMQPLTDLPFVFWDERLSTVAAERALIGMDVSRGKRADRIDSAAAAFILQGALDRLHMMRRNDYDAG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_CALS4
Sequence: MAIQIVLIVGPTATGKSRLAVDVAKRFNGEVVSADSMQIYKYMDIGTAKITKEEMQGIPHHMIDIVEPNEEFSVAEYEKRAKAIIKDIHERGKLPIIVGGTGLYINSIVYIMHFSDFEGSKEFREKMKKLAETYGTSYLYEKLKEVDPEAARKIHPNDLRRIIRALEVYEFTGKPISHYQKMSGMRKNPEYDPIMIGLNYKNRQLLYEKINRRVDEMIKNNLVEEVVNLLKIGYNKYGTSMQALGYKEIVEYLNGEISLEEAVEKIKKGTRRYAKRQITWFKAYDFIKWFFVDDYKTYEELRENIFEYLAGKLKF
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: HSLO_STAA8
Sequence: MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIADANAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIMVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVGLGVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNCSHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPN6_SCHPO
Sequence: MSSKSSLELANNAVKSNDIEKAIDLYKEVLNKGVSKDEKVANEQEQALTNLSDLYVRENRHNDLAQLVQQSRPLMANFSKAKSAKIVRTLIDKFSGEKKSLPLQIEVANDCIKWAIKEKRTFLRQALETKLISLYYDNSSYTDAINLINTLLSELKRMDDKMLLTEVHLLESKVYHAIRNIPKARASLTAAKTSANAVYCPPMLQGNLDLQSGILHADDMDFKTAYSYFYEAYEGFTSLDDDKKALSSLKYMLLSQIMLNSVSEVKSLLTGKHAIRYAGRDIEAMRAIAQAHENRSLADFEKALQDYKPELASDPIIRSHLSSLYDNLLEQNLLRVVEPFSRVEVSHIAELIGLSTVQVEGKLSQMILDKIFYGILDQGSGCLIVYDEPQQDKTYEAALEVIKNMGTVVDLLIENKASALL
What is the function of this protein?
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  In the complex, rpn6 is required for proteasome assembly (By similarity).
What are the official names of this protein?
Probable 26S proteasome regulatory subunit rpn6.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S9 family.
Protein: SYK2_MYCPU
Sequence: MNENIKLTEQEIIRREKLKKYEDLGVETFKKFDHEKINIYSNEINQKYSNLTKDELLEKQIKLIVAGRILTQRGPFIVIQDTNGKIQLYIDKKELEERKETLALLDIGDIIYVKGTLMKTMKGELTIKVNFFDLLTKGLTPLAEKYHGLVDVEERYRKRYLDLISNPNIKEIFWTRTKIISKIREFFDKQNFMEVETPMLHSILGGASARPFKTYHNSLSSSFNLRIATELPLKKLLVGGIDRVYEIGRIFRNEGIDTTHNPEFTSIEFYQAYSNLEIMMEQTENLIKFIAKELGLSKIKNHDVEIDLLADFKKINMVDAVSEATKVDFRNIDLNKAIEIAKSYKIKVEKYFKVGHIINELFELLIEKTLIQPTFVMGYPIEVSPLAACSKDKRFTERAELFINTKEYANMFTELNDPLDQRRRFEAQFEEKESGNEEASEIDEDFLNALEYGLPPAGGCGIGIDRLVMLLTQKESIREVILFPTLKKKQL
What are the official names of this protein?
Lysine--tRNA ligase 2, Lysyl-tRNA synthetase 2, LysRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACS1_DEBHA
Sequence: MTPHSTHVTLDHEGIIQPPAEFKERSKSKPNLADFETYSKMYKESIENPSKFFGEQALEHLSWDRPFDEARYPVSSEQDFADGDIASWFVNGQLNASYNAVDRWAIKNPNKPAIIYEADEENEGRIITYGQLLKDVCKLAQCLTKLGIRKGDSVAVYLPMIPEALVTLLAIVRIGAVHSVVFAGFSSSSLKDRILDASSKIVITTDESKRGGKTIETKKIVDDALKNCPDVTNVLLFKRTGNAHIPFTEGRDLWWHEEMAKYGPYFPPVPVNSEDPLFLLYTSGSTGKPKGIQHSTAGYLLGAAMTSKYTFDVHEDDVLFTAGDVGWITGHTYVVYGPLLCGATTVVFEGTPAHPNYSRYWEIVDKYQVTQFYVAPTALRLLKRAGTKYIENYKLDSLRVLGSVGEPIAAEIWHWYNDNIGRRKCHIVDTYWQTESGSHMLAPLAGITPTKPGSASLPCFGIDAKILDPVSGKELKENDVEGVLCVKSCWPSISRGIYNDYARFIETYLKPYPNHYFSGDGAARDVDGFYWILGRVDDVVNVSGHRLSTAEIEAALILHESVAECAVVGYADELTGQAVAAYVSLKSNVSEDLEVIKKELILTVRKEIGPFATPKTILLVDDLPKTRSGKIMRRILRKVLAGEEDQLGDISTLSNPGVVAQIIDVVKATRK
What are the official names of this protein?
Acetyl-coenzyme A synthetase 1, Acetate--CoA ligase 1, Acyl-activating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RS18_KLEP3
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: URTF_STAAS
Sequence: MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI
What are the official names of this protein?
Probable uridylyltransferase SAS2072.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 1 family.
Protein: DAPB_STRGC
Sequence: MGIKIIIAGFKGKMGQAAYKMVTEDPELELVGLLDPFTDEKEVAGVPVFNAKEELAGLEAHVWVDFTTPKVAYDNTRFALEQGFCPVVGTTGFTPEQLEELITLSREKQLGGLIAPNFALGAVLLMQFAAQAAKYFPNVEIIELHHDQKKDAPSGTAIKTAELISQVRPSKQQGAADEEESIAGARGAYFDGMRIHSVRLPGLVAHQEVIFGSQGEGLTLRHDSYDRASFMTGVNLAIKEVVKRSELVYGLEHLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAQR8_MOUSE
Sequence: MTTAILERLSTLSMSGQQLRRLPKILEEGLPKMPCTVPETDVPQLFREPYIHAGYRPTGHEWRYYFFSLFQKHNEVVNVWTHLLAALAVLLRFWAFVEAGALQWASPHTLPLLLFILSSITYLTCSLLAHLLQSKSELSHYTFYFVDYVGVSVYQYGSALAHFFYSSDQAWYELFWIFFLPAAAFCGWLSCAGCCYAKYRYRRPYPVMRKICQVVPAGLAFVLDISPVAHRVALCHLAGCQEQAAWYHTLQILFFLVSAYFFSCPVPEKYFPGSCDIVGHGHQIFHAFLSVCTLSQLEAILLDYQGRHEIFLQRHGPLSVYSACLSFFVLAACSAATATLLRHKVKDRLIKKDS
What is the function of this protein?
Plasma membrane progesterone (P4) receptor coupled to G proteins.  Seems to act through a G(i) mediated pathway (By similarity).  May be involved in oocyte maturation (PubMed:12601167).  Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (By similarity).
What are the official names of this protein?
Membrane progestin receptor beta, mPR beta, Lysosomal membrane protein in brain 1, Membrane progesterone P4 receptor beta, Membrane progesterone receptor beta, Progesterone and adipoQ receptor family member 8, Progestin and adipoQ receptor family member 8, Progestin and adipoQ receptor family member VIII.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalizes with a lysosomal protein CTSD/cathepsin D.
Protein: GLMU_LISMF
Sequence: MSKRYAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDQISTLNVDKVVTIVGHGAEKVQEHLAGKSEFVKQEEQLGTAHAVLQAKAELAGKDGVTLVVCGDTPLIEASTMEALLKYHHEKRAKATILTTVIEDPTGYGRIIRDDLGIVEKIVEHKDATEKEQRISEINTGTYCFDNKALFEALENVSNDNVQGEYYLPDVIKILKDSDEVVAAYRMESFEESLGVNDRIALAEASRLMQRRINENHMRNGVTLVNPENTYIDIDVKIGQDTVIEPGVMLRGETVIGDDCVVTSGSEIVNSVIGERVHVRTSSIFESKVGDDVQIGPYAHLRPESDIHDHVKIGNYVETKKAVVGEGTKLPHFIYMGDAEIGKNVNVGCGSIAVNYDGKNKAKTIIGDNVFVGCNSNLIAPVKVGDRAFIAAGSTITKDVPDDALGIARAKQDNKLGYAKHLNHGK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHD_BACHK
Sequence: MKEIEKLKEEYPLLNKLIATEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASYIAKVFPETKETKGIIESPLLKIPSMKQALEKNYEQPILGELLLKCDSHLPISGSIKARGGIYEVLKHAEQLALQHGMLTEEDNYAILDSDTCREFFATYSIAVGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGRRQADADPSCYFVDDENSHDLFLGYAVAASRLQKQLEELKIVVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFAEPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDAYLQKQQLMEKVQKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: LEXA_LEPIC
Sequence: MKDLTDKQQAVLAFITAIIKERGFPPTIREIGDEFGITAKGAYDHLKAIEKKGYLKTAKNQSRAIELIRQSPMESLPVQATSIPVIGQVAAGLPIFAEENIESYIPVPDEMAKGNVPMYALRVQGDSMIEVGINDGDIAIIEKRDIARNGEIVVALIEDEATLKVYYKEQDQIRLEARNPKYKPIKTKKATVMGKLIGLYRIY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: AROC_CHESB
Sequence: MSHNTFGHLFRVTTWGESHGPAIGCVVDGCPPGIHFTQAEIQADLDRRRPGQSRFVTQRREPDEVKILSGVMQDGETLVTTGTPISMLIENVDQRSKDYGEIAERYRPGHADYTYDAKYGVRDYRGGGRSSARETATRVAAGALARKIVPGMVVRGALISMGEKEIDRANWDWDFLHDPENPFFTPDPKSVSEFADYLDGVRKAGSSVGAVIEIVAEGVPAGLGAPLYGKLDQDICANLMSINAVKGVEIGIGFQAARIHGEENADEMRSGNDGYPRFLSNNAGGILGGISTGQPIIARFAVKPTSSILTPRRSIDRKGAEVEVVTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGKG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: AIDAA_XENLA
Sequence: MSDMNKILHKWSASLKKGTDFDSWGQLVEAIDEYQILARQLQKEAQSPANSSDFTEDQKKTIGKIATCLGLRSAALQYTQSQEGFTLEDVKKLEPILSSIVTFNKEFPFDVQPVPLRRILAPGEEENLEVDEEEEDGGAGIGSPDLFPARVPGTLLPRLPSEPGMTLLTIKIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPMATRKEDTYVHFNVEIEIQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGQTVIELYKKPTDFKRKKLQLLTKKPLYLHLLQTLLKD
What is the function of this protein?
Acts as a ventralizing factor during embryogenesis.  Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization.  This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by axin/JNK-signaling (By similarity).
What are the official names of this protein?
Axin interactor, dorsalization-associated protein A, Axin interaction partner and dorsalization antagonist A.
What is the protein family that this protein belongs to?
Belongs to the AIDA family.