PharMolix/UniProtQA huggingface dataset:
Protein: ERA_RICBR
Sequence: MTKQIQKTVSVCIIGRPNSGKSTLLNRIIGEKLSIVTPKVQTTRSIITGIITLNDTQIILYDTPGIFEPKGTLEKAMVRCAWSSLHSADIVMLIIDSLKPLDSITHDILNKLRSLNVVPVFLLNKIDVESKYIDDTKAFLAENYSDSLLFPISAISGENVDKLLEYITSKAKIAPWLYEEDDITDLPMRFIAAEITREQLFLGLQQELPYKLTVQTEKWEELKDKSVKINQIIVVSRESYKTIILGKNGSKIKELGAKSRMQMQQFFGFPVHLFLFVKVQELWEDNSDYYEYMKI
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: IF2B_METTH
Sequence: MDDYEKLLERAIDQLPPEVFETKRFEVPKAYSVIQGNRTFIQNFREVADALNRDPQHLLKFLLRELGTAGNLEGGRAILQGKFTHFLINERIEDYVNKFVICHECNRPDTRIIREGRISLLKCEACGAKAPLKNV
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: LIPB_ACICJ
Sequence: MDRAVSTTTNAVEWAKAPGLTDYPSALAEMQARAAAIRAGEEAERVWLVEHPPLYTAGTSARDADLLHPGDAQVFRSGRGGQWTYHGPGQRVAYVMLDLSRPHGRVPARDVRGFVAGLEAWLIDTLAGFGVRGELREGRVGIWVANPLGGESKIAAIGVRVSRWVSYHGIALNVAPDLGRFGGIVPCGISEHGVTSLAALGVAATLDAVDAALARSFERVFDAAPQPV
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_ACTPJ
Sequence: MSQIKLIVGLANSGTKYEDTRHNAGEWLINEIARQFNVSLKEEAKFFGKVAKINAAGGEVRLLVPTTFMNLSGKAVGALANFYRIKPEEILVAHDELDLPPGVAKIKQGGGHGGHNGLKDIIASLGNSNNFYRVRIGIGHPGSKELVAGYVLGKPSPQDQEKINAAVDEAGRCVDLLLKDGITKATNRLNAFKA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_GEOSW
Sequence: MAIKKYKPTSNGRRGMTVLDFSEITTDQPEKSLLAPLKKKAGRNNQGKITVRHQGGGHKRQYRIIDFKRDKDGIPGRVATIEYDPNRSANIALIHYADGEKRYIIAPKNLKVGMEIMSGPDADIKVGNALPLENIPVGTFVHNIELKPGRGGQLVRAAGTSAQVLGKEGKYVIVRLASGEVRMILGACRATVGEVGNEQHELVKIGKAGRARWLGIRPTVRGSVMNPVDHPHGGGEGKAPIGRKSPMTPWGKPTLGFKTRKKKNKSDKFIIRRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CYSH_PSEAB
Sequence: MPPFATIPATERNSAAQHQDPSPMSQPFDLPALASSLADKSPQDILKAAFEHFGDELWISFSGAEDVVLVDMAWKLNRNVKVFSLDTGRLHPETYRFIDQVREHYGIAIDVLSPDPRLLEPLVKEKGLFSFYRDGHGECCGIRKIEPLKRKLAGVRAWATGQRRDQSPGTRSQVAVLEIDGAFSTPEKPLYKFNPLSSMTSEEVWGYIRMLELPYNSLHERGYISIGCEPCTRPVLPNQHEREGRWWWEEATHKECGLHAGNLISKA
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCF8_ORYSJ
Sequence: MEEVVVGGKERKRPRGALVGVGGGGASAATAAAWRTSRVARAAAGGKDRHSKVVTSRGLRDRRVRLSVPTAIAFYDIQDRLGVDQPSKAIEWLIRAAAAAIDALPSLDCSFALPAAASSPPPPAADDAEVSTSETSKSSVLSLANAPCDNGGGAFAELLHCSNTNGSKPLQQQQQATLAYYAAAQSAHMAAPMSFEVMAMPPHLAFSQEQQQHATVAAFDRGTLQSNASLWPPPPQPPPSQHPFLLQRFAAAPAEVAGLPFFLAGGVGGAAAAAPAATTNGGERRLQLWDFKEERKT
What is the function of this protein?
Transcription activator.  Binds the promoter core sequence 5'-GGNCC-3'.
What are the official names of this protein?
Transcription factor PCF8.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMM_ECOSE
Sequence: MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIEFCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEAALGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CRTC3_HUMAN
Sequence: MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHGGSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL
What is the function of this protein?
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.  Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation.  Enhances the interaction of CREB1 with TAF4.  Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR.  Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells.  Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
What are the official names of this protein?
CREB-regulated transcription coactivator 3, Transducer of regulated cAMP response element-binding protein 3, TORC-3, Transducer of CREB protein 3.
What is the protein family that this protein belongs to?
Belongs to the TORC family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Appears to be mainly nuclear (PubMed:15454081). Translocates to the nucleus following adenylyl cyclase or MAP kinase activation (PubMed:30611118).
Protein: RL1_STRPM
Sequence: MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEVAYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVAKINGGWLDFDVVIATPDMMAIVSRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQGVGIKVDPNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YJLB_BACSU
Sequence: MERETQTYFFPDDGRIPNHPDFPLVVYQNALKDTGLAERIVTRHGWSNSWSGSVFPYHHYHSNTHEVLIALRREAVIQFGGEKGAAIPFKSGDAVVIPAGVGHKKLSSSPDFTVLGAYPGGVQYDMKTGKPNEREEAVKQIKQAALPANDPITGKREPLLEIWVK
What are the official names of this protein?
Uncharacterized protein YjlB.
Protein: BUK1_CALS4
Sequence: MGLALILVINPGSTSTKVAVFRDKEPVFTETLRHSTEELSKYKRIIDQFEFRTQAILDMLKEKGISLSQIDAIVGRGGLLKPIESGTYIVNEKMLEDLKKAERGEHASNLGAIIAYTLAKEHNIPAYIVDPVVVDELEDVARITGLPEIEKQSIFHALNQKAIARRLASDLGKRYDEVNLIIAHLGGGISVGAHRKGRVIDVNDALNGEGPFSPERAGGLPVLDLVKLCYSGKYTFEEMKKKLIGKGGIVAHLGTNDVREVYKMIENGDKNAELILDAMAYQTAKEIGSMAVVLKGKVDAIGITGGIAHNEDFVRRIRERVEFIAPVYVYPGEDEMLALAEGAYRVLTGEENPKTYS
What are the official names of this protein?
Probable butyrate kinase 1, BK 1, Branched-chain carboxylic acid kinase 1.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS49_CVBON
Sequence: MKTKFVFDLLAPDDILHPSNHVNLIIRLI
What are the official names of this protein?
Truncated non-structural protein of 4.9 kDa, Truncated ns4.9, Truncated 4.9 kDa accessory protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns4.9 protein family.
Protein: DAPB_PROMH
Sequence: MSATELRLAVVGAGGRMGRQLIQAINQQQGVVLGAAFERTNSSLIGADAGELAGIGHIGITVTDNLLAQVGQFDILIDFTRPEGTLSHLAFCVEHHKGMIIGTTGFDEEGKKAINCAAQTIPIVFAANFSVGVNLVLKLLEKAAKVMGSYSDIEIVEAHHRHKVDAPSGTALAMGESIAETLGRDLKDCAVYQRVGHTGERDPRSIGFATIRAGDIVGEHTAIFADIGERVEISHKASSRMTFANGAVKSAIWLSEKKSGLYNMKDVLSLEEL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CKLF6_MOUSE
Sequence: MENGAVYSPTTEAAPGTGRGARSGLAAYFVLGRLPWHRRILKGLQLLLSLLAFICEEVVSECGLCGGLYFFEFVSCSAFLLSLLLLIVYCTPVHDRVDTGKVKSSDFYITLGTGCVFLLASIIFVSTHSGTSAEIAAIVFGFLASSMFLLDFVVMLCEKLRESPLRKPENNAKVEALTEPLNA
What is the function of this protein?
Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity.  Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination.  May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.
What are the official names of this protein?
CKLF-like MARVEL transmembrane domain-containing protein 6, Chemokine-like factor superfamily member 6.
What is the protein family that this protein belongs to?
Belongs to the chemokine-like factor family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Recycling endosome membrane. Note=Co-localizes with PD-L1/CD274 in the plasma membrane and in recycling endosomes.
Protein: UDGB_MYCBO
Sequence: MHPKTGRAFRSPVEPGSGWPGDPATPQTPVAADAAQVSALAGGAGSICELNALISVCRACPRLVSWREEVAVVKRRAFADQPYWGRPVPGWGSKRPRLLILGLAPAAHGANRTGRMFTGDRSGDQLYAALHRAGLVNSPVSVDAADGLRANRIRITAPVRCAPPGNSPTPAERLTCSPWLNAEWRLVSDHIRAIVALGGFAWQVALRLAGASGTPKPRFGHGVVTELGAGVRLLGCYHPSQQNMFTGRLTPTMLDDIFREAKKLAGIE
What is the function of this protein?
DNA glycosylase with broad substrate specificity.
What are the official names of this protein?
Type-5 uracil-DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.
Protein: VMA21_DROSI
Sequence: MSTKNKKAAGGNGGAPKQTRQQSHDSQDYSSFKTVLFYCMLIVFLPVLTFFVLKGFVLDQFLDISEVKVNIASAVGAVVALHIALGLYIYRAYFGAPGSKGSKTD
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein VMA21 homolog.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: RL3_PSELT
Sequence: MKMILGRKIGMTRLFINDVSIPVTVVRAGPCYVVQKKNPQIDGYCAIQVGFEHLKRVNKPLEGHFKKAQVKPLRLLREIRLEDENELDSYEIGQEIKLDIFQPGEKVDITGWTKGRGFSGGIKRWGFSGGPRAHGSKFHRELGSLGQHTEPAKIFKGKKMPGRYGNERVTIHNLEVIKIDLENNLLVLKGSVPGARGSLVIIKSPRRTRK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: KHSE_BACVZ
Sequence: MNEAEMLFSITVPGSTANLGPGFDSVGMALSRYLKLSVFRNDEWQFSAETETVAGIPQGTDNLIYQVAKRTADRYQKELPPAHVKVWSDIPLARGLGSSAAAIVAAIELADELCGLQLSESDKLHLASLEEGHPDNAAASLAGGLVIGLHEEGETHIVRVAEADIDVVAVIPFYEVLTRDARDVLPKELPYRHAVKASAVSNLLVAAIMSNDWALAGKMMRKDILHQPYRAMLVPELSKVEHAAEMKGAYGTALSGAGPTILVLIEKGKGEELRKQLSEHFPHCEIAALTVPSEGSVIERNPLEQVKSV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_MYCBT
Sequence: MGLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDIARFGMERFSATPRQADLMIVAGRVSQKMAPVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVDHVVPVDIYLPGCPPRPEMLLHAILKLHEKIQQMPLGINRERAIAEAEEAALLARPTIEMRGLLR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DEOB_RHIME
Sequence: MARAFLFVLDSFGIGNAPDAEAFGDLGADTLGHIAEFCAAGAADRAGLREGPLHLPNMSALGLMHAARLATGRLPAGMALPERVYGIYGAASEVSRGKDTPSGHWEIAGTPVTFDWGYFPAEGDAFPPELVEAICREGDVPGILGNCHASGTDIIARHGEEHMRSGKPICYTSSDSVFQIAAHEQTFGLERLLNLCEVVRRLVDDYNIGRVIARPFVGSDPGSFTRTGNRRDYSVLPPEPTVLDRLQEAGRTVHAIGKIGDIFAHQGVTRLTKANGNMALFDASLEAIEEAEDGALVFTNFVDFDMLYGHRRDVSGYAAALEAFDARLPDLDRRLKPGDMVILTADHGCDPTWRGTDHTRERVPVLMFGPTLRSRSFGIADSFAHIGETVARHLGIGVGPHGRSLI
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADEC_METTP
Sequence: MRIEDLIAAARGELEADLLLEGGKLVNVFSGEIHRADISIYGGFVAGFDCPSARRVISVEDHLIAPGSIDAHVHIESSMLMPSEYARAVVPRGTLTVIADPHEIANVLGVDGISYLLRCAEGIPMRFLVTAPSCVPATHLETSGAALGVSEIASLLDDHRVVGLGEMMNYPGVIHRDKPVLAKLKVAASKNKTICGHAPGLGGRDLHAYAAALIEDDHECTRAEEAMEQLRAGICIMIREGSAARNLDELVKIIREYNTPNIMLCTDDLDPRDIVHRHIDHMIRRIIEAGTDPVAAIQMATINPARHFGLRRTGAVAPGYRADIIVMDHDFNVRRVIFEGEEVARDGRLTASFESKRLPVQTSMNVRLPITRESFRIPATGRIVRVIGVAPNQILTETIAARPEVRNGEVISDTRNDILKVAVVERHRATGNVGLGLVSGFGLKRGAIASSVSHDSHNIIVVGEDEESMVRAVESLISMGGGWVSVDGTTIASLPLPIAGLLSERRVEDVVEEAENVIAASHSLGSELEDSFMTLSFLALPVIPELRITDRGLVDVREFGHVPLFME
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: TAL_JANSC
Sequence: MKFFVDTADIDAIRELHELGMVDGVTTNPSLIMKSGRDIKEVTAEICALVDGPVSAETVALDADGMINEGRELAKIADNITIKVPLTWAGLQACKVLSGEGRMVNVTLCFSANQALLAAKAGATFISPFVGRLDDLNMDGMDLIAEIRQIYDNYGFETEILVASIRSANHMKDAALIGADVATAPPGVIKAMANHVMTDKGLDAFMADWAKTGQSIV
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB5A_BOVIN
Sequence: MANRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSTRGRGVDLTEPTQPTRSQCCSN
What is the function of this protein?
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states.  In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:16476778) (By similarity).  RAB5A is required for the fusion of plasma membranes and early endosomes.  Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan.  Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.
What are the official names of this protein?
Ras-related protein Rab-5A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Cytoplasmic vesicle. Cell projection, ruffle. Membrane. Cytoplasm, cytosol. Cytoplasmic vesicle, phagosome membrane. Endosome membrane. Note=Enriched in stage I melanosomes. Alternates between membrane-bound and cytosolic forms.
Protein: RNH2_BORBU
Sequence: MICGIDEVGRGCIFGPILSAAVVFKKKPSFIKELDDSKKLKKEKREYLSSLILENSYYAFAEISNITIEKINIHNASLLAMQTAYENLKLNCSLVLVDGKFVPKITAKNVKAIIKGDSIIDEIKAASIIAKVKRDKLMDKYDKIYPLYLLKKNKGYPTKEHKNAIKKYGVLSLHRKNFKLI
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y606_STAS1
Sequence: MVKVYIAGPIPEVGLNLLKDQGFEVDMYEGTGIIDKETLKQGVKDADALISLLSTSVDKEVIDAANNLKIITNYGAGFNNVDIDYARQQNIDVTNTPKASTNSTAELTFALVLAVARRIPEGDKLCRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAVARRAKAFDMNILYTGPHQKVDKEREIGAKYVDLETLLKNADFVTINAAYNPSLHHQIDKAQFEMMKPTSYLINASRGPIVHEKALVQALKDKEIEGAALDVFEFEPEINDELKTLDNVVITPHIGNATFESRDMMSKIVANDTISKLNNDQPKFIVN
What are the official names of this protein?
Putative 2-hydroxyacid dehydrogenase SSP0606.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: ACCD_XANCP
Sequence: MSWLSKLMPSGIRTENTPAKKRSVPEGLWEKCSNCGSALYGPELEENLEVCPKCDHHMAIRARARLAALFDLDSPTTEIAAQLGPVDVLKFKDQKKYGERIKASQKSSGEYDALIAMRGMLKGNPLVAAAFDFAFMGGSMGSVVGERFARAAEVALEVGCPFVCFSASGGARMQEGLFSLMQMAKTSAALGRLREAGLPYISVLTHPTTGGVSASFAMLGDINIAEPHALIGFAGPRVIEQTVRETLPEGFQRSEFLLDHGAIDQICDRRDMRDRIAELTTMMMRQPHPQDADAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTDT_SHIFL
Sequence: MKPSTEWWRYLAPLAVIAIIALLPVPAGLENHTWLYFAVFTGVIVGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSVIWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSARGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLLIGLMKSASHATLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETELQAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSNKAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTMVMVTLIVVFYLLRYFFASATAYTCALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYGSGYLPTADYWRLGAIFGLIFLVLLVITGLLWMPVVLL
What is the function of this protein?
Catalyzes the uptake of tartrate in exchange for intracellular succinate.  Essential for anaerobic L-tartrate fermentation (By similarity).
What are the official names of this protein?
L-tartrate/succinate antiporter, Tartrate carrier, Tartrate transporter.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TI214_CHAGL
Sequence: MITTYSTFLFNFLSQFQYLVNIPEPLILFGLYYGFLTTLPISFSHIVVIRNRLIEGKTSSVMAFCGLITGQLCMIGTIYYTPLYKLFIKPHLILLLSIIYSFFYWQRLRNNQNYDDLREAQSLINVRNFFSFFDSFVFQILNPILLPTPIFFRLNNVFLFRYSNNLNFFLSFFIGSLIGNFLFFNALNWIRYRFEQDSNVIYPVLKLLINKSIIPIVFCICLIPIAKYSHIPFCTMKQKEGQSSYSFDKNWPNIIFDSNQPHRPIRIFSETKTDDNLNINDNLSKKQTSQFFFKECISDGNVRISYTYPSTLANFQTDLSSSFQDFSLSEQSFDNLYSNWKLEKLSRKDNLNNLLLTKIKLLNNKKEWFYKHFQNKFGTFIKDDNNYNKFVKKSNDVRLKQSSKIQIKKSKLLTSDIRDISTTQSGFYDLKKNKLKSFISQKFKMNSNNSTLPVWNHLNKQLLQNELKRIKKQLQDKTKNIKENDFNNLKLLKSNIETIDNTINDIHHNKIKQITSVDLIKIFATNNKTLLLETLAFNKKITQKDNFNFNKLFQHKNKKFTTNSGNENTYLNLNDIFKNIKRLPKWRTFSKHVVYDEVSDIRRRAIKSNSKLKIANKDSDIIIFEYKKSLNFRARLPKGSLRARRKNKFTWKLFHNNLNSPFFIRSKQLLNKTDIPFLKYNENYLNFFKNFISPDKNINYLNNDISEMRRQELLFKWDKTNVHILRSMVLVGQAFFRKYIKLPIFIFFKNLSRQLLYQPSEWTKDWSNWMNEWYIFCYYDGTELAKDQWPEMWLQRGIQIKLINPFYIKPWYIQKSFIKNKQNKKTRTSYLTVFGSQQELPFGKKIRMPSFWKPVRREVSKSIKLKLYFPFLTLQKNTIILFEKVFNKKRINEDNKTIEKSILNKKNEQLILKKDEVIPNNKSIAGKLSKLDFHNQNITKTSIKNATKQILIKNEYNSLLKENKNLFTKNKIVFLKIKNILNKLNLKLIKVKINFTYKIKTVLKIISRNLLKFYSIIQFQLENLGRNNSNDLSYKNQLSYQKDFPNFNNFCLNQANIIQNLCKNNILKHKKLNQNFQINSKNLNQTNIIDVNPENIKAQDFKNLLENIYTFTPTINLWDKLSTNNWKISVQNNWKQKSYNNYDLTKKALVSKNLNFISYFYQNNLINNLNKKIKHTKIFNLSKNYLSLNNLNQNQIKNFDFQNSLNNNITYKKNIKNFTIRQNVPSQLRRWDWKNNKIKKFVNRLLQKNTILLKEEVFNLIPFFDRFTIQNPMIRNWSHPISSILDDEIFTYELLDTFLQINKNIDFLHTKQIEDNLSSNSNQAIASLPLSSTTAENFLYYLTTVEDLISIEDKKELKILNSLNFNKSTPNYIKTNVVEKSLNENLSKNLQSILSKETLDSINNTQILKKFLWASYRCEDLACMNRFWFSTNNGSRFGTLRLRLYPNLKN
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.