PharMolix/UniProtQA huggingface dataset:
Protein: SYT_NITMU
Sequence: MAVVRLPDGSERVYEHSVTVGEVAASIGAGLARAALAGKVNGKLVDLSARIENDSDVAIITEKDAEGLEIIRHSSAHLLAHAVKELFPEAQVTIGPVIEDGFYYDFSYKRPFTPEDLAAIEKRMAEISTRNLKVERQVWDRSEAINFFKNQGEHYKAQIIEAIPGDEDVSLYSQGNFTDLCRGPHVPATSRLKVFKLMKLAGAYWRGDSHNEMLQRIYGTAWTNKDDQNAYLRRLEEAEKRDHRKLGKQLGLFHLQEEAPGMVFWHPKGWVVWQQVEQYMRDIFRNNGYLEIRTPSVLDKGLWERSGHWENFRENMFVTQAEDREFSVKPMNCPGHVQVFKQGLKSYRDLPLRLAEFGSCHRNEPSGALHGIMRVRAFTQDDAHIFCTESQVQDEAVQFIDLLQKVYNDFGFNDILVKLSTRPAKRVGSEEQWDKAEEALRSALNHKNLIWELQPGEGAFYGPKIEFSLKDSIGRIWQCGTLQLDFSMPERLGAEFVAEDNSRQIPVMLHRAILGSLERFIGILIENHAGALPLWLSPDHAVVLNISEGQADYAREVTEELRRAGIRAYADLRNEKITYKIREHSLQKLPYQIIVGDKEVAAQRVAVRTRSGSDLGQMTLPALVDRLKEEIRTRAGAA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_STRT2
Sequence: MISGIINLKKEAGMTSHDAVFKLRKILHEKKIGHGGTLDPDVTGVLPIAVGKATRVIEYMTEAGKVYEGEITIGFSTTTEDASGEVVQTTPITELDGATVDQAMASFEGEITQIPPMYSAVKINGKKLYEYARAGEEVERPQRQVKITEFVRTSPIELENGTARFTFRVACSKGTYVRTLSVDLGVKLGFASHMSALRRTASAGLTLDSSLSLSQISEMVEAGDQSFLLPIEFGVQDLPAVQVTEDDAKEISFGRFISINSQEPLVAAFLGDKVLAIMEKRGQVYKPRKVLSQ
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: MNTP_CLOPE
Sequence: MSILSIVLTGFGLAMDAFAVSVAKGITLTRVKAKDALKVALFFGGFQALMPLIGWGAGRYFADYIKAFDHWIAFILLSFIGGKMIFEALKEDDEEKAEVAVSMEVSKNKEREFANMKRKEELSAKNLTVLAIATSIDALAVGVSFAFLGISIVQTIIIIGIITFVLCFLGVIIGEKLGDIFKNYAEIVGGVILILIGINILLEHTGIIEKLFS
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDUV1_BOVIN
Sequence: MLAARRLLGGSLPARVSVRFSGDTTAPKKTSFGSLKDEDRIFTNLYGRHDWRLKGAQSRGDWYKTKEILLKGPDWILGEVKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEGEPGTCKDREIIRHDPHKLVEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAGLIGKNACGSGYDFDVFVVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPTTVANVETVAVSPTICRRGGAWFASFGRERNSGTKLFNISGHVNNPCTVEEEMSVPLKELIEKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALIQAQTGLGTAAVIVMDRSTDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVRGDARPAEIDSLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPELEERMQQFAQQHQARQAAF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, Complex I-51kD, CI-51kD, NADH dehydrogenase flavoprotein 1, NADH-ubiquinone oxidoreductase 51 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: MUTS_ANADE
Sequence: MPEIAQAHTPMMRQYLETKARYPDAILFFRLGDFYEMFFEDALTASEALQITLTARSKGDDKVPMCGVPYHAARGYVARLLEKGFKVAICDQVEEPGKSQLVKREVTRVVTPGMVLDDQVLDPREASWLGAVALEGGRAGLALLDASTGQLQCGEVDGDERLVDELRRAGVRELVFSSAADGARTEAIARAVGAPAARRDAAEFERAEDRLRKHLGVPSLDGFGVSGLPLGLSAAAAALAYLADTQRAAPRHVDRISRLSTDDVLLLDEATRTNLELERTLSGGRKKGTLLALLDRTVTAPGGRRLAEWLRYPLADLARIGARLDAVEELSGASVAREELAGALRPVADLERLLSRLVLGQGNARDLRALAGALLALPALADVLEARGAALLREAGGRLRGLEALAAHLDAAVAEEPPATLREGGFIRRGHSAELDEIVAISEDGKGWIAGLEAKERERTGIGSLKVRFNKVFGYYLEVTKPNLHLVPKDWERRQTTVGGERFVTPELKGFEEKVLTAEERRAALEERLFEALRQAVAAEAPRVRTAADAVATADALLSLARVAAERGYVRPEVDASEALEIVDGRHPVVEAVLPDGPAAYVPNDVLVASRGAPECAEHGALLVITGPNMAGKSTVMRQAALVVLLAQMGAFVPARRARIGLVDRIFTRVGASDDLARGRSTFMVEMTETAAILHNATRRSLVVLDEIGRGTSTFDGVSIAWAVAEHLHDVTGCRTLFATHYHELQDLARERPAVRNLTVAVREVGDRVVFLRKLVQGGASRSYGIEVAKLAGLPAEVLARAREILKNLEAMEVDEGGHPALARGRRRRAGPAAAQLGLFGGGAAADPAADEVAKAIRALDLDALRPLDALNLLAGWKRSLE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: TRHO_YERPP
Sequence: MPVLHNRISNEELKARMLAETEPRTTVSFYKYFTLEDAKTFRDNLYSQFVKLGVFGRVYVAKEGINAQISVPANRYDEFKIALFASHPALDQVRLNVAHEDDGKSFWVLRLKVRERIVADGIDDDSFDPANIGHYLKADQVNQMIDDPDTLFVDMRNHYEYEVGHFENAIEVPSDTFREQLPMAVDMLQHDKEKNIVMYCTGGIRCEKASAYMLHNGFKNVYHVEGGIIEYARKAKEQGLPLKFIGKNFVFDERMGERISDDVIAHCHQCGTPCDAHTNCKNDGCHLLFIQCPVCAAKFEGCCSQICQEELKLPQEEQRSRRAGRENGIKIFNKSKGLLQATMHIPSPEKSADEK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: PSAF_GRATL
Sequence: MKKICVLFCMIILYTSINPINSLAEVETAGLTKCQESPAFTKRLNNSVKKLETRLAKYDANTPPAIALQTQIIKTKIRFNKYAKSGILCGTDGLPHLITDGRWNHAGEFMIPGVLFLYITGWIGWVGRGYLRDISQTTKPTEKEIILDVPLALKYCLSGFTWPLAAIKELTSGELVADNKDIPISPR
What is the function of this protein?
Probably participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria).  This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.
What are the official names of this protein?
Photosystem I reaction center subunit III, PSI-F.
What is the protein family that this protein belongs to?
Belongs to the PsaF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: GLNE_MYCUA
Sequence: MNVTKPATQRPKLPSVGRLGLVDALAGAHLAELGWTEHDDQAHVDLLWSLSRAPDADAALKVLVRLAENPDTGWDELNAALLNERSLRGRLFAVLGSSLSLGDHLVANPQSWKLLRGKVALPSHAALLESFVDLAEEVAAAPASAVHRLRALHRDHVLVLAGLDLAATVEDEPVLSFTVVAAHLADIADAALAAALRLAEKTVCRDRTPPRLAVIAVGKCGARELNYVSDVDVIFVAERADPISIRVAGEMMRVASSTFFEVDAGLRPEGRSGELVRTVESHIAYYQRWAKTWEFQALLKARAAVGDAELGQRYLAALMPMVWTACERDDFVAEVQAMRRRVEQLVPADIRGRELKLGTGGLRDVEFVAQLLQLVHGRSDESLHVASTVDALSALGEGGYIGREDAANMIASYEFLRLLEHRLQLQRLKRTHLLPEFDDEEAVRWLARAAHIRPDGRHDAAGMLREELKHQNVRVSRLHAKLFYQPLLESIAPAGLEIAGRGMTSEAAERQLAALGYEGPQTALKHMAALVNHSGRRARVQSVLLPRLLDWLSYAPDPDGGLLAYRRLSEALAPQSWYLSTLRDKPTVGRRLMHVLGTSAFVPDLLMRAPEVIQNYGDSRTGPKLLETEPAAVARALIASAGRYSDPLRAIAAARTLRRRELARIGSADLLGLLEVTEVCRALTSVWVAVLQSALEAMIRANTPEGGRPLARIAVIGMGRLGGSELSYGSDADVMYVCEPASGVTDAQGVKWSTAVAEQVRAKLGTPSVDPPLEVDANLRPEGRNGPLVRTLASYGAYYAQWAQAWEIQALLRAHAVAGDAALGQRFLLLVDHTRYPPDGVSAEAVHEIRRIKARVESERLPRGADPNTHTKLGRGGLADIEWTVQLLQLQNAHEIEALHNTSTLESLDAIAEAKLVAEDEVKLLRQAWLTATRARNALVLVRGKPTDQLPGPGRQLNAVAVAAGWHNDDGGEFLDNYLRVTRRAKAVVRKVFGS
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: EFTU_MICLC
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAISKVLYDKYPDLNEARDFATIDSAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMAQTREHVLLARQVGVPALLVALNKSDMVEDEELLELVEMEVRELLSSQEFDGDEAPVIRTSGLKALEGDPQWVKSVEDLMDAVDEYIPDPVRDKDKPFLMPIEDVFTITGRGTVVTGRAERGTLKINSEVEIVGIRDVQKTTVTGIEMFHKQLDEAWAGENCGLLLRGLKRDDVERGQVVVEPGSITPHTNFEANVYILSKDEGGRHNPFYSNYRPQFYFRTTDVTGVITLPEGTEMVMPGDTTEMSVELIQPIAMEEGLGFAIREGGRTVGSGRVTKITK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_STRPN
Sequence: MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNYTRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: NUSB_SYNP6
Sequence: MQPRRIARELALLSLSQLPAKAEPPSDQMLSELLLAATRTLAAEARDHLEAASAELKQSSDRLLLSTLGSADLESSRAMLQEVIEMAQAAINRTGNALDLPEWVQLTDREEVRKFGGRLVLQVSNNRERIDRTLNDVMVDWQLHRVPRLDQDILRLAAAEILFLGTPEQVAINEAVELANRYSDEEGRRFINGVLRRLSTMLGKAARAARPSS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ACPS_POLNA
Sequence: MIYGLGTDICDIRRIRASLERHGERFAQRILSDAELATWTARSARWPDRGVSYLATRFSAKEAFSKAIGLGMRMPMTWRHCEIANAASGKPEIVLHGALKDWFDARQLTAHVTVSDETDYAASFCVVEKK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSE1_ASPFU
Sequence: MATTSNMFMYSLTIQPPTAITQAILGQFAGTKEQQIVTASGSKLTIHRPDPTQGKITPIYSQDVFGIIRTLAAFRLAGSSKDYIIIGSDSGRITIIEYVPSQNRFNRIHLETFGKSGVRRVVPGQYLAVDPKGRACLIASVEKNKLVYVLNRNSQAELTISSPLEAHKPQTVVFAMTALDVGYENPIFAALEVDYSEADQDPTGRAYEESEKLLVYYELDLGLNHVVRKWADPVDRTASMLFQVPGGADGPSGVLVCAEDNITYRHSNQDAFRVPIPRRIGATENPERKRSIVAGVMHKMRGAFFFLLQTEDGDLFKVTIDMVEDDNGQLTGEVKRLKIKYFDTVPIASSLLILKSGFLYVASEAGNHHFYQFEKLGDDDEETEFNSENFPADLSVPCEPVFFQPRGAENLNLVETLNSLNPLIDSKIVNLNEDDAPQIYTVSGSGARSSFRTLKHGLEVSEIVESELPSVPSAVWTTKLTRADEFDAYIILSFANGTLVLSIGETVEEVTDTGFLSTAPTLAVQQLGEDSLIQVHPRGIRHILADRRVNEWPAPQHRSIVAAATNERQVAVALSSGEIVYFEMDADGTLAEYDERRQMSGTVTCLSLGEVPEGRVRSSFLAVGCDDSTVRILSLDPDSTLENKSVQALTSAPSALNIMSMADSSSGGTTLYLHIGLYSGVYLRTVLDEVTGELSDTRTRFLGAKPVKLFRVSVKGQTAVLALSSRPWLGYSDIQTKGFMLTPLDYVGLEWGWNFSSEQCVEGMVGIQAQNLRIFSIEKLDNNILQESIPLSNTPRRMLKHPEQPLFYVIESDNNVLSPATRARLIEDSKARNGETNVLPPEDFGYPRATGHWASCIQIVDPLDAKAVISTIELEENEAAVSMAAVPFSSQDDETFLVVGTAKDMIVNPPSSAGGFIHIYRFQEDGKELEFIHKTKVEEPPLALLGFQGRLLAGIGSTLRIYDLGMKQLLRKCQAQVVSKTIVGLQTQGSRIVVSDVRESVTYVVYKYQDNILIPFVDDSVSRWTTSTTMVDYETVAGGDKFGNLWLVRCPKKASEEADEDGSGAHLIHERGYLHGAPNRLDLMIHTYTQDIPTSLHKTQLVAGGRDILVWTGFQGTIGMLVPFVSREDVDFFQNLEMQLASQCPPLAGRDHLIYRSYYAPVKGVIDGDLCEMYFLLPNDTKMMIAAELDRSVREIERKISVRYANEGSVLIILMAIPASVCKGL
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle control.
What are the official names of this protein?
Pre-mRNA-splicing factor rse1.
What is the protein family that this protein belongs to?
Belongs to the RSE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LYTA_STAAU
Sequence: MQAKLTKNEFIERLKTSEGKQFNVDLWYGFQCFDYANAGWKVLFGLLLKGLGAKDIPFANNFDGLATVYQNTPDFLAQPGDMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWTDGIEQPAGVGKKLQDDNMLMISLCGLSVRILKVRQRHDQFNLLHKHPKKETAKPQPKAVELKIIKDVVKGYDLPKRGSNPKGIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYVSGNTVWQALDESQVGWHTANQIGNKYYYGIEVCQSMGADNATFLKNEQATFQECARLLKKWGLPANRNTIRLHNEFTSTSCPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYMDGKIPVATVSNESSASSNTVKPVASAWKRNKYGTYYMEESARFTNGNQPITVRKVGPFLSCPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEIS
What is the function of this protein?
Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation.  Autolysin strictly depends on the presence of choline-containing cell walls for activity.
What are the official names of this protein?
Autolysin, N-acetylmuramoyl-L-alanine amidase.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: COX2_ONCFA
Sequence: MATWMNINLQDANSSTMEQLTMFHDHTLMILTMITSIVTFIMVSMTTNTLINRYLLEGQTIEFIWTTIPAITLIFIALPSLHLLYLIDEINNPEMTLKVIGHQWYWSYEYSDFKNIEFDSYMKPTNELMNNEFRLLEVDNRVLLPMNKQIRILITAADVLHSWAIPSLGVKIDATPGRLNQGSIKINRPGILFGQCSEICGANHSFMPIVIESVPIKNFLKWINKSLSS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y7243_DICDI
Sequence: MIDYKINEILVKQLNDDYNCSICVDPVLNSLPLEQHQALSCKNGHLLCQACWGKQLALRKECCICKIKVESISELCRNIFLEKGFRNKKVHCPNGFENFKVDEKLIKDESDGCKSVITIDQLESHLRECEFVFIECPNDPIRCKDKFRKNQTDKHMNKCQYVTINCEHCKEPVIKNDMPTHIENDCSIISLECEFCKDKFGRRSLENHIANECPNVVIDCPHKEGGCTARIKRCYLSQHLTEEDNHIRYMQKIIEKHRIQVEESDRIIKKLRVDYKELEKRVEITSRYKGNWTIENWSQKLTHYPNNERLKSPYFCIGSKSFYVGLYPNGFNQTNAGFMSIFLHLYEKPSTSTTVVRFSFELLHSDPTKSLKFEKSNKYTENKGSGFSQFIDIKMINNFIIDGKLTINIDVEVIPPSSSLVTK
What is the function of this protein?
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
What are the official names of this protein?
TNF receptor-associated factor family protein DDB_G0277243.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_PSYIN
Sequence: MRLCDTHIEEYLDAGKIVITPRPPKSAISGVSVDIRLGNEFRVFSEHTTPYIDLSGPKEEVSSALDKVMSEPIIIAKNESFFLHPGELALAVTYENVTLPDDIVGWLDGRSSLARLGLMVHVTAHRIDPGWSGKIVLEFYNSGKIPLALRPEMTIAALNFEVLSAPAARPYNKRVDAKYQVQQGAVASRINQDN
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: MOAC_PSE14
Sequence: MLTHLDSQGRANMVDVTDKAVTSREAVAEAVVRMLPTTLQMIVSGGHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLTSIKVHLAADGDDAVRITASCKLAGQTGVEMEALTAASIAALTIYDMCKAVDRGMVIESVRLLEKLGGKSGHFIADQAQVSS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: ADAL_HUMAN
Sequence: MIEAEEQQPCKTDFYSELPKVELHAHLNGSISSHTMKKLIAQKPDLKIHDQMTVIDKGKKRTLEECFQMFQTIHQLTSSPEDILMVTKDVIKEFADDGVKYLELRSTPRRENATGMTKKTYVESILEGIKQSKQENLDIDVRYLIAVDRRGGPLVAKETVKLAEEFFLSTEGTVLGLDLSGDPTVGQAKDFLEPLLEAKKAGLKLALHLSEIPNQKKETQILLDLLPDRIGHGTFLNSGEGGSLDLVDFVRQHRIPLELCLTSNVKSQTVPSYDQHHFGFWYSIAHPSVICTDDKGVFATHLSQEYQLAAETFNLTQSQVWDLSYESINYIFASDSTRSELRKKWNHLKPRVLHI
What is the function of this protein?
Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine (PubMed:21755941, PubMed:29884623).  Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A) (PubMed:21755941, PubMed:29884623).  Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro (PubMed:21755941).
What are the official names of this protein?
Adenosine deaminase-like protein, Adenosine deaminase-like protein isoform 1, N6-mAMP deaminase, HsMAPDA, N6-methyl-AMP aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: BIOD_FRAT1
Sequence: MKKFFIIGTDTEVGKTYISTKLIEVCEHQNIKSLCLKPVASGQSQFSELCEDVESILNAYKHKFTAAEINLISFNQAVAPHIIAAKTKVDISIENLKQFIEDKYNQDLDILFIEGAGGLLTPYSDHTTQLDLIKALQIPVLLVSAIKVGCINHTLLTINELNRHNIKLAGWIANCNDSNIKYIDEQINTIEELSGYKCSAKISRNADYLDFIDLSKILISPEENE
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_NITSB
Sequence: MNFENNSTIAAIATAYGVGSIAIVRISGPKSLSIAQKLSKKKDIQPRVAHLVTLYDDQSEPIDQAILIYFQAPKSFTGEDVVEFQCHGGVVVANMILQELLKAGARLANPGEFSKRAFFNGKIDLSEAEAIAKMIEAKSEDAAKILAKQIKGELKNYIENLREKLIRILAYVEVNIDYAEEDLPKDLQEQIEQQLNDIQEELQKIVASSKRRAGLIEGFKVAIIGKPNTGKSSLLNALLDYERAIVSDIAGTTRDTIEESVRIGTHLVRFVDTAGIREAHDTIEKIGIERSIQAIEESDIVIAMFDASKPLDAEDKKILELIESYKDQKEFIVVANKVDKGKHLDLSDFDALYMSVKKEITPLTQKLQKLLDSFANTEEIMLVTSRQIEAVTYALENINQARTPLQMGELEIFAFHINRVIESIGSITRPMQSSELLDKMFGEFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_ROTH3
Sequence: MGKYNLILSEYLSFIYNSQSAVQIPIYYSSNSDLEKRCIEFHSKCLENSKKGLSLKNIFLEYKDVTENATLLSILSYSYDKYNAVERKLVHYAKGKPLEADLNANELDYENNKLTSDLFPTAEEYTDSLMDPAILTSLSSNLNAVMFWLERHANDTAERAKIYKRRLDLFAIVASTVNKYGVPRHNAKYRYEYEVMKDKPYYLVTWANSSIEMLMSVFSHEDYLIAKELIILSYSNRSTLAKLVSSPMSILVALVDINGTFITNEELELEFSNKYVRAIVPDQTFDELKEILDNMKKAGLVDIPKMIQDWLVDCSIEKFPLMAKIYSWSFHVGFRKQKMLDAALDQLKTEYTEDVDDEMYREYTMLIRDEVVKMLEEAVKHDDHLLQDSELAGLLSMSSASNGESRQLKFGRKTIFSTKKNMHVMDDMANGKYTPGVIPPVNVDKPIPLGRRDVPGRRTRIIFILPYEYFIAQHAVVEKMLIYAKHTREYAEFYSQSNQLLSYGDVTRFLSNNAMVLYTDVSQWDSSQHNTQPFRKGIIMGLDILANMTNDAKVIQTLHLYKQTQINLMDSYVQIPDGNVIKKIQYGAVASGEKQTKAANSIANLALIKTVLSRIANKYSFVTKIIRVDGDDNYAVLQFNTEVTKQMVQDVSNDVRDTYARMNAKVKALVSTVGIEIAKRYIAGGKIFFRAGINLLNNEKRGQSTQWDQAAVLYSNYIVNRLRGFETDREFILTKIMQMTSVAITGSLRLFPSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQRAFMSLSSQKSGIADEIAASQTFKNYVSKLSDQLLVSKNVIVSRGIALTEKAKLNSYAPVSLEKRRAQISALLTMLQKPVTFKSNKITINDILHDIKPYFVTSEANLPIQYQKFMPTLPNNVQYIIQCIGSRTYQIEDDGSKSAISRLISKYSVYRPSIEELYKVISLHEQEIQLYLVSLGIPKIDADTYVGSKIYSQDKYRILESYVYNLLSINYGCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHLYAKLEIINYAIKNGSWISLFCNYPKSEMIKLWKKMWNITSLRSPYTNANFFQD
What is the function of this protein?
RNA-directed RNA polymerase that is involved in both transcription and genome replication.  Together with VP3 capping enzyme, forms an enzyme complex positioned near the channels situated at each of the five-fold vertices of the core.  Following infection, the outermost layer of the virus is lost, leaving a double-layered particle (DLP) made up of the core and VP6 shell.  VP1 then catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded through the DLP's channels into the cytoplasm where they function as mRNAs for translation of viral proteins.  One copy of each of the viral (+)RNAs is also recruited during core assembly, together with newly synthesized polymerase complexes and VP2.  The polymerase of these novo-formed particles catalyzes the synthesis of complementary minus-strands leading to dsRNA formation.  To do so, the polymerase specifically recognizes and binds 4 bases 5'-UGUG-3' in the conserved 3'-sequence of plus-strand RNA templates.  VP2 presumably activates the autoinhibited VP1-RNA complex to coordinate packaging and genome replication.  Once dsRNA synthesis is complete, the polymerase switches to the transcriptional mode, thus providing secondary transcription (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, Protein VP1.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging (By similarity).