PharMolix/UniProtQA huggingface dataset:
Protein: VP4_ROTF1
Sequence: MASLIYRQLLSNSYVTNISDEVNEIGTKKTTNVTVNPGPFAQTGYAPVDWGHGELPDSTLVQPTLDGPYQPTSLNLPVDYWMLIAPTREGRVAEGTNTTDRWFACVLVEPNVQNTQRQYVLDGQNVQLQVSNDSSTSWKFILFIKLTPDGTYTQYSTLSTPHKLCSWMKRDNRVYWYQGSSPNASESYYLTINNDNSNVSSDAEFYLIPQSQTAMCTQYINNGLPPIQNTRNIVPVNIASRQIKDIRAQMNEDIVISKTSLWKEMQYNRDIIIRFKFANSIIKSGGLGYKWSEISFKPMNYQYTYTRDGEEVTAHTTCSVNGVNDFNYNGGTLPTDFAISRFEVIKENSYVYVDYWDDSQAFRNMVYVRSLAANLNDVVCSGGSYSFALPVGNHPVMSGGAVTLTSAGVTLSTQYTDYVSLNSLRFRFRLAVSEPSFSISRTRMSGIYGLPAVNPNNNAEYYEIAGRFSLISLVPTNDDYQTPIANSVTVRQDLERQLGELREEFNSLSQEIAVSQLIDLATLPLDMFSMFSGIKSTVEAVKSMTTNVMKRFKTSSLANAISDLTSNMSEAASSVRLTSVRSIGTVTLPRARVSLQVSDDLRSMQDVSTQVSNVSRNLRLKEFTTQTDTLSFDDISAAVLKTKLDKSTQISQQTMPDIIAESSEKFIPKRSYRIVDEDTAFETGIDGTFYAYKVDTFNEIPFDMERFNKLITDSPVLSAIIDFKTLKNLNDNYGITKKQAMELLHSNPKTLKEFINNNNPIIRNRIENLISQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: NU1C_PSINU
Sequence: MIIFMKDFEEQVMNLVNLLGISKDLFFILWTVLSILTLLLGVTMGVLVIVWLERKISAGMQQRMGPEYTGPLGILQTLMDGIKLLLKEDIVPAKGNTWLFNLGPAIVVIPVFLSYLVIPFGQKMILSDLGIGVFFWIAVSSIVPLGLLMTGYGSNNKYSFLGGLRAAAQSISYEIPLALCVLSISLLSNSLSTVDIVEAQSKYGILGWNLWRQPVGFIVFIVSSLAECERLPFDLPEAEEELVAGYQTEYSSIKFGFFFIGSYLNLLVSSLFVTVLYLGGWDLSLPFLPGLNHITMTWYSSDGITEVPSIFLSFFITLIKAFLFLFVSIAARWTLPRVRMDQLLDLGWKFLLPIALGNLLLTASFQLLLLG
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ACYP2_ANAPL
Sequence: MSTLGKAPGALKSVDYEVFGRVQGVCFRMYTEEEARKLGVVGWVKNTSQGTVTGQVQGPEDKVNAMKSWLTKVGSPSSRIDRTNFSNEKEISKLDFSGFSTRY
What is the function of this protein?
Its physiological role is not yet clear.
What are the official names of this protein?
Acylphosphatase-2, Acylphosphatase, muscle type isozyme, Acylphosphate phosphohydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: PRRC1_DANRE
Sequence: MMEESGIESTPPATPPPPSTVVASPPPLTSGATRPQTVPSPSGISAFTPGDFSSPVPSVALTSTLPPMQSSVPPLPLSSISSPLGLSGPYGIPSASFASPAAGPPLSTGPPLGPVLSAPPMGPPTTGFSVSGGYDITRGHAGRTPQTPLMPSFSSASPMPGIVTNPMMQQPVSGGLDVSSPITFPEDVEDPRVTPDSNAPGGLWGFIKGVAGNPMVKTVLDKTKHSVESMITTLDPGMAPYIKSGGDVDIVVTSDKEVKVAAVRDAFQEVFGLAMVTGEAGQSNIAPQPVGYAAGVKGAQERIDSLRRAAVIHEKQPVVSVENFIAELFPDKWFDIGCLILDDPGYGIHIETFTQATPVALEHVQQAQSLTPPDYNLRWSGLLVTVGEVLERNVPNVSRTDWHQAFTGMSRRQMIYSAAKALAGMYKLRLPSRTV
What are the official names of this protein?
Protein PRRC1, Proline-rich and coiled-coil-containing protein 1, Protein misty somites.
What is the protein family that this protein belongs to?
Belongs to the PRRC1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: NPD_LISMO
Sequence: MNKLNEALKKAERIVFLTGAGVSVPSGIPDYRSKNGLYAGMSSPEYMLSHTCLVREPEKFYQFVTENMYYPNAVPNVIHKKMAEIETEKDVTIITQNIDGLHEKAGSKKVVNFHGSLYHCYCQNCGMTVTAKDYLKSDIHTDCGGVIRPDVVLYEEAISESAIDQSLTAIRKADLIVIVGTSFRVSPFCNLTDYRNKKARIFAVNKERISLPYPFEMMESDAVKVFEEI
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTA_RABIT
Sequence: MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, aortic smooth muscle, Alpha-actin-2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SMAD4_HUMAN
Sequence: MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTMPIADPQPLD
What is the function of this protein?
In muscle physiology, plays a central role in the balance between atrophy and hypertrophy.  When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4.  MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8.  Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.  Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions (By similarity).  Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor).  Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling (PubMed:25514493).  Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription.  Component of the multimeric SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site; required for synergistic transcriptional activity in response to TGF-beta.  May act as a tumor suppressor.  Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
What are the official names of this protein?
Mothers against decapentaplegic homolog 4, MAD homolog 4, Mothers against DPP homolog 4, Deletion target in pancreatic carcinoma 4, SMAD family member 4, SMAD 4, Smad4, hSMAD4.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
Protein: PHL1_LEPIN
Sequence: MITKRNIPPCKKNWKYKKKSISLTLITICYMFLFLTSCKPGKKNSINLLLLLLNTLDNKNVNEKIEDSTNTDPSSNVNEEDENSINANANDNAPSDSDSSNPRSPDKNPVNPTSPNSSSADIGIKILSHSIFMAPTNLSSWGDLGQEERAQRIASSSYIKNQDIIVFEGLSHNNAEKILLEKIRSEYPYQTNVVGRTKKGWNATLGAYTTSPMANGGVIIVSKWPIEEKVQYIFNNSNCGQDQYYNKGFAYVKINKDGKKFHVIGTQLQAREPDCFNSGETIRKLQLNDIKSFIDSKDIPKDETVLITGDLNIIKGSNEYFDMISKLNVNEPRYVGVPFTLDTKTNALAAYYYEKEKPIYLDYILVSKLHAQPPVWQNLAYDPISNTTWKRSDGYTSYEFSDRYPVYGFIYADSSTPTKSGHKRKYDQVSFQSTFNRKFIQADHNKKDGWLKADTRIKTDFTKFNLLQENVSESNPSCMNSGSVRIESSYYLNYYWNWFIGAASGDYGYYTKFNNGSDSLGIKNLDNGCLKDGSRVAFYDWDTIGGGYYYLTVWDKGSWKEHLFLWVQSFLSSREIFYLHLDSNPPKDWSKDLIYHH
What are the official names of this protein?
Sphingomyelinase C 1, Sphingomyelin phosphodiesterase 1, SMase 1.
What are the subcellular locations of this protein?
Secreted.
Protein: NCLX_MOUSE
Sequence: MASRWLALLWAPVFLCVALILETASGTGDPSTKAHGHIQFSAGSVNQTAMADCRAVCGLNTSDRCDFVRRNPDCRSEAGYLDYLEGIFCYFPPNLLPLAITLYVFWLLYLFLILGVTAAKFFCPNLSAISTNLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPRTAGLAIGALFGAGVLVTTVVAGGITILHPFMAASRPFLRDIAFYMVAVFLTFTALYLGRITLTWALGYLGLYVFYVVTVIICTWVYQRQRSRSLVHSISETPELLSESEEDQMSSNTNSYDYGDEYRPLLLGRETTVQILIQALNPLDYRKWRTQSISWRVLKVVKLPVEFLLLLTVPVVDPDKDDRNWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWAVVVIVGTALASVTFFATSNREPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVIFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQIIRNHVVEVKLEPDGLLVWVLASALGLSLIFSLVSVPLQCFQLSKAYGLCLLLFYICFLVVVLLTEFGVIHLKKA
What is the function of this protein?
Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, by mediating the exchange of 3 sodium ions per 1 calcium ion (PubMed:20018762, PubMed:28445457).  Plays a central role in mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion: calcium efflux is essential for mitochondrial function and cell survival, notably in cardiomyocytes (PubMed:24067497, PubMed:28445457).  Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses (By similarity).  Required for store-operated Ca(2+) entry (SOCE) and Ca(2+) release-activated Ca(2+) (CRAC) channel regulation: sodium transport by SLC8B1 leads to promote calcium-shuttling that modulates mitochondrial redox status, thereby regulating SOCE activity (By similarity).  Involved in B-lymphocyte chemotaxis (PubMed:27328625).  Able to transport Ca(2+) in exchange of either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange (By similarity).  In contrast to other members of the family its function is independent of K(+) (By similarity).
What are the official names of this protein?
Mitochondrial sodium/calcium exchanger protein, Na(+)/K(+)/Ca(2+)-exchange protein 6, Sodium/calcium exchanger protein, mitochondrial, Sodium/potassium/calcium exchanger 6, Solute carrier family 24 member 6, Solute carrier family 8 member B1.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Note=Mainly localizes to mitochondrion inner membrane (PubMed:20018762). SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane; Multi-pass membrane protein.
Protein: F16PA_VIBA3
Sequence: MSEMRTLGEFIVEKQSDFPHASGDLSSLLSSIRLAAKIVNREINKAGLVDITGAVGTDNVQGEEQQKLDLYANDKFKAALEARDQVCGVASEEEDEAVAFNKELNKNAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVSPVGTPPTQEDFLQPGHKQVAAGYVIYGSSTMLVYTTGAGVNGFTYDPSLGTFCLSHENMMIPDEGKIYSINEGNYIRFPTGVKKYIKYCQENEPSDNRPYTSRYIGSLVSDFHRNLLKGGIYLYPSTQSHPQGKLRLLYECNPIAFIMEQAGGIASDGAQRIMDIKPTELHQRVPFFVGSKNMVKKVEEFLELNRD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB3I_HUMAN
Sequence: MGLKKMKGLSYDEAFAMANDPLEGFHEVNLASPTSPDLLGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYSSPRRLNCAEISSISFHVTDPAPCSTSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDGSDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVREANIKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLPGGKTPFKKGHTRNKSTSSAMSGSHQDLSVIQPIVKDCKEADLSLYNEFRLWKDEPTMDRTCPFLDKIYQEDIFPCLTFSKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKSCKHRIKLGDSSNYYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B (PubMed:12221131, PubMed:26824392).  Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (PubMed:12221131, PubMed:26824392).  Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5 (PubMed:20937701, PubMed:26824392).  Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface (PubMed:12221131).  Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (PubMed:20890297).
What are the official names of this protein?
Rab-3A-interacting protein, Rab3A-interacting protein, Rabin-3, SSX2-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the SEC2 family.
Protein: TP8L2_MOUSE
Sequence: MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPKAQRVIKDLIKVAVKVAVLHRSGCFGPGELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLVECRDILLELVEHHLTPKSHDRIRHVFDHYSDPDLLAALYGPDFTQHLGKICDGLRKLLDEGKL
What is the function of this protein?
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis.  Negative regulator of Toll-like receptor and T-cell receptor function.  Prevents hyperresponsiveness of the immune system and maintains immune homeostasis.  Inhibits JUN/AP1 and NF-kappa-B activation.  Promotes Fas-induced apoptosis.
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 8-like protein 2, TIPE2, TNF alpha-induced protein 8-like protein 2, TNFAIP8-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
Protein: MABA_MYCBO
Sequence: MTATATEGAKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMTRALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGGMGMGH
What is the function of this protein?
Part of the mycobacterial fatty acid elongation system FAS-II, which is involved in mycolic acid biosynthesis.  Catalyzes the NADPH-dependent reduction of beta-ketoacyl derivatives, the second step of the FAS-II elongation cycle.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase MabA, 3-ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase, Beta-ketoacyl-acyl carrier protein reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: MURE_BORGP
Sequence: MNKKLKDVLLKLDQDLIKHVKGSLDLEISGVTYSSKLVLPRYVFFALPGIRFDGHDFIETAIQKGSNVIVCSRDMDFYSPNVTYIKVDDFNIRKFMSNFSNIFYDEPSKKLKVIGVTGTDGKSSVCYYIYLLLKKKGVKVGFISTVFFDDGNGSLIKNPYRQSTPESTEIHLFLSNMVKNNVQYAILESTSHGLDLKTARLIDVNYFAVVFTNIGHEHLEFHGTIQNYLNAKLGLFRSVSDDAGFGVINFDDPYYSDFKNAVKKSFTYSLKSSKADFFVSFIDEKIDSTRFEFYHKGVKYFANVSLLGSFNVENIMAALILVSQILNSDIQDIVDKLICIKSLDGRMDSVNLGQNFSVIIDYAHTPGAFSKLFPIFKRFATNRLISVFGSAGERDVAKRFLQGQIADIYSDLIVLCDEDPRGENSMYIIKDIAKGIVNKVVNQDLFFIPDRRLAIEKAISLARAGDLVVALGKGHENSIIYKNKELFWNEQEAVKNAILSLEESEKDR
What is the function of this protein?
Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramyl-tripeptide synthetase, UDP-MurNAc-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEG3_HUMAN
Sequence: MLPPKHLSATKPKKSWAPNLYELDSDLTKEPDVIIGEGPTDSEFFHQRFRNLIYVEFVGPRKTLIKLRNLCLDWLQPETRTKEEIIELLVLEQYLTIIPEKLKPWVRAKKPENCEKLVTLLENYKEMYQPEDDNNSDVTSDDDMTRNRRESSPPHSVHSFSDRDWDRRGRSRDMEPRDRWSHTRNPRSRMPPRDLSLPVVAKTSFEMDREDDRDSRAYESRSQDAESYQNVVDLAEDRKPHNTIQDNMENYRKLLSLVQLAEDDGHSHMTQGHSSRSKRSAYPSTSRGLKTMPEAKKSTHRRGICEDESSHGVIMEKFIKDVSRSSKSGRARESSDRSQRFPRMSDDNWKDISLNKRESVIQQRVYEGNAFRGGFRFNSTLVSRKRVLERKRRYHFDTDGKGSIHDQKGCPRKKPFECGSEMRKAMSVSSLSSLSSPSFTESQPIDFGAMPYVCDECGRSFSVISEFVEHQIMHTRENLYEYGESFIHSVAVSEVQKSQVGGKRFECKDCGETFNKSAALAEHRKIHARGYLVECKNQECEEAFMPSPTFSELQKIYGKDKFYECRVCKETFLHSSALIEHQKIHFGDDKDNEREHERERERERGETFRPSPALNEFQKMYGKEKMYECKVCGETFLHSSSLKEHQKIHTRGNPFENKGKVCEETFIPGQSLKRRQKTYNKEKLCDFTDGRDAFMQSSELSEHQKIHSRKNLFEGRGYEKSVIHSGPFTESQKSHTITRPLESDEDEKAFTISSNPYENQKIPTKENVYEAKSYERSVIHSLASVEAQKSHSVAGPSKPKVMAESTIQSFDAINHQRVRAGGNTSEGREYSRSVIHSLVASKPPRSHNGNELVESNEKGESSIYISDLNDKRQKIPARENPCEGGSKNRNYEDSVIQSVFRAKPQKSVPGEGSGEFKKDGEFSVPSSNVREYQKARAKKKYIEHRSNETSVIHSLPFGEQTFRPRGMLYECQECGECFAHSSDLTEHQKIHDREKPSGSRNYEWSVIRSLAPTDPQTSYAQEQYAKEQARNKCKDFRQFFATSEDLNTNQKIYDQEKSHGEESQGENTDGEETHSEETHGQETIEDPVIQGSDMEDPQKDDPDDKIYECEDCGLGFVDLTDLTDHQKVHSRKCLVDSREYTHSVIHTHSISEYQRDYTGEQLYECPKCGESFIHSSFLFEHQRIHEQDQLYSMKGCDDGFIALLPMKPRRNRAAERNPALAGSAIRCLLCGQGFIHSSALNEHMRLHREDDLLEQSQMAEEAIIPGLALTEFQRSQTEERLFECAVCGESFVNPAELADHVTVHKNEPYEYGSSYTHTSFLTEPLKGAIPFYECKDCGKSFIHSTVLTKHKELHLEEEEEDEAAAAAAAAAQEVEANVHVPQVVLRIQGLNVEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEAAEPIGEAGQPNGEAEQPNGDADEPDGAGIEDPEERAEEPEGKAEEPEGDADEPDGVGIEDPEEGEDQEIQVEEPYYDCHECTETFTSSTAFSEHLKTHASMIIFEPANAFGECSGYIERASTSTGGANQADEKYFKCDVCGQLFNDRLSLARHQNTHTG
What is the function of this protein?
Induces apoptosis in cooperation with SIAH1A.  Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage.  Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity).  Possesses a tumor suppressing activity in glioma cells.
What are the official names of this protein?
Paternally-expressed gene 3 protein, Zinc finger and SCAN domain-containing protein 24.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ITPA_NEUCR
Sequence: MSAPSQARHIVNFITGNANKLGEVKAILEPAIQVENQALDLLEIQGTLEEVTLDKCRRAADLVQGPVLVEDTCLCFNALKGLPGPYIKWFMNSLGHEGLNNLLAAYEDKSAKAVCTFGYSAGPGHEPILFQGITDGKIVPPRGPPNFGWDAIFEYEGQTYAEMDKAEKNKISHRAKALAKLQEWFAKEMTA
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1363_MYCTO
Sequence: MAETTEPPSDAGTSQADAMALAAEAEAAEAEALAAAARARARAARLKREALAMAPAEDENVPEEYADWEDAEDYDDYDDYEAADQEAARSASWRRRLRVRLPRLSTIAMAAAVVIICGFTGLSGYIVWQHHEATERQQRAAAFAAGAKQGVINMTSLDFNKAKEDVARVIDSSTGEFRDDFQQRAADFTKVVEQSKVVTEGTVNATAVESMNEHSAVVLVAATSRVTNSAGAKDEPRAWRLKVTVTEEGGQYKMSKVEFVP
What are the official names of this protein?
Uncharacterized protein MT1408.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1362c.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ABDA_ARTSF
Sequence: PNGCPRRRGRQTYTRYQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARKDREEQEHKIRSSSSDDGSIGKGVGIPLDASLLKSNDSQSVSLNHLTHKSPDGMMDKTPKSII
What is the function of this protein?
Required for segmental identity of the second through eighth abdominal segments.  Once a pattern of abdA expression is turned on in a given parasegment, it remains on the more posterior parasegment, so that the complex pattern of expression is built up in the successive parasegments.  The abdA product appears to repress expression of Ubx whenever they appear in the same cell, but abdA is repressed by AbdB only in the eight and ninth abdominal segments.
What are the official names of this protein?
Homeobox protein abdominal-A homolog.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RELL1_MOUSE
Sequence: MALWGLPGSAVLAASVFVGGAVSSPLVAADNTGSHTLHSRAETTPSSPTNNPGNGHPEYIAYVLVPVFFVMGLLGVLICHLLKKKGYRCTTEAEQEVEEEKVEKIELNDSINENSDTVGQIVQYIMKNEANADILKAMVADNSVGDIESPVTPSTPGSPPVSPGPLSPGATPGKHVCGHHLHTVGGVVERDVCQRCRHKRWHFIKPTNKTKEGRPRRQGEVTVLSVGRFRVTKVEHKSNQKERRSLMSVSGIESVNGDVPATPVKRERSDTE
What is the function of this protein?
Induces activation of MAPK14/p38 cascade, when overexpressed.  Induces apoptosis, when overexpressed.
What are the official names of this protein?
RELT-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the RELT family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RL332_STRGG
Sequence: MAATDVRPKITLACVECKERNYITKKNRRNNPDRLEMKKHCPRCNSHTAHRETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PTH_MYCCT
Sequence: MKVIIGLGNIGKEYEKTRHNAGFIAIDLLLEKYKYNSIKEEFNSLVYTSIINNQKVLFVKPLTFMNNSGLTVKQIINFYKIDLNDLIVIHDDKDLNISRIQFKKDGSSAGHNGIKSIINNLNTQDFYRLRIGINKPANQWKIVDWVLSKFSDDELNLLKESFNNKSEFINDFTNNKTFTYLMNKYN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y14C_BPT4
Sequence: MRLQRQSIKDSEVRGKWYFNIIGKDSELVEKAEHLLRDMGWEDECDGCPLYEDGESAGFWIYHSDVEQFKADWKIVKKSV
What are the official names of this protein?
Uncharacterized 9.5 kDa protein in frd-Gp32 intergenic region.