PharMolix/UniProtQA huggingface dataset:
Protein: MNMG_LIGS1
Sequence: MEFGKRYKAKDYDVIVVGAGHAGCEAALASARMGNETLLITINLEMVAFMPCNPSIGGPAKGIVVREIDAMGGEMGRNIDKTYVQMRMLNTGKGPAVRALRAQADKRQYSIEMKHTIEQTPHLTLRQGIVDDLIIEDGEVKGVVTNTGACYGAKSVVLTTGTAARGKIIIGELMYSSGPNNTQPALELSKNLAKLGFELKRFKTGTPPRVDGNTIDYDKTEEQPGDVEPNHFSYESKDEDYLKVKDQLSCWLTYTNEYTHKIIQDNLDRAPMFTGVIEGVGPRYCPSIEDKIVRFSDKPRHQLFLEPEGRNTDEYYVQGLSTSLPEEVQQEMVRSIDGLEHAEMMRPGYAIEYDVVSPYQLRPTLETKLIKGLYTAGQTNGTSGYEEAAGQGFIAGVNAGRRAKGLEEITLKRSDAYIGVMIDDLVTKGTNEPYRLLTSRAEYRLILRHDNADLRLTELGHEIGLISDERYAAFEEKKAQIEAEKQRLSKIRIKPNAEVNAFVEAHGDRELKDGVLATEFLRRPYVTYQDLLKFIPAPAEPLDRRVIEQIEIQFKYEGYIKKEYAKVEKLKRMEAKKIPARIDYSRIEGIATEAQQKLAKIQPETLAQAGRISGVNPADLSILAVYIEQGKIARVDD
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KARG_HOMGA
Sequence: MADAATIAKLEEGFKKLEAATDCKSLLKKYLSKDIFDSLKAKKTSLGATLLDVIQSGVENLDSGVGIYAPDAEAYSLFAPLFDPIIEDYHKGFKQTDKHPAKDFGDVSKFINVDPEGTFVISTRVRCGRSMEGYPFNPCLTEAQYKEMEEKVSSTLSGLEGELKGSYFPLTGMTKEVQQKLIDDHFLFKEGDRFLQAANACRYWPAGRGIYHNDNKTFLVWCNEEDHLRIISMQMGGDLGQVYRRLVSAVNDIEKRVPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAAKFSLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEM
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: QUEA_ANAD2
Sequence: MRLSDFDFALPEGLVAQAPVTPRDASRLMVLAPEEGSPAHRGFADLPELLAPGDLLVFNDTRVIPARLLGHKASGGKVELLLCEPLEGGLGRRWRAMGQASKPIREGAVLTFDGLEARVDDVEGEGFYRVTLDRQGPELEAALGRAGRIPLPPYIRRAPDAEDAARYQTIWARAPGSAAAPTAGLHFTEPLLARLAARGIRRTAVTLHVGPGTFLPIRGDDLDLHRMHGERYEVSPAAAAELAATRARGGRIVAVGTTSVRTLESAWRDGAVAAGPGRTELFIRPGHPFHAVDAMVTNFHLPRSTLLVLVCAFGGQGRVLAAYREAVARGYRFFSYGDAMLLLRR
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_FRACC
Sequence: MPPKKKKITAIIKLQINAGKATPAPPVGPALGQHGVNIMEFCKQYNAATESQAGNVVPVEITVYDDRSFTFVTKTPPAARLILKAAGVEKGSGTPHRDKVAKLTTAQIREIAQTKLPDLNATSIEAAEKIIAGTARSMGITVGE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NU4C2_NOSS1
Sequence: MNTANFPWLTTIILLPIAASLLIPIIPDKDGKTIRWYALTVGLIDFALIVYAFYTSYDFANPDLQLVESYPWVPQLDLNWSVGADGLSMPLIILTGFITTLATLAAWPVTLKPRLFYFLLLAMYGGQIAVFAVQDMLLFFLVWELELIPVYLLLAIWGGKKRQYAATKFILYTAGGSLFILLASLTMAFYGDTVTFDMRSLALKDYALNFQLLLYAGFLIAYAIKLPIIPLHTWLPDAHGEATAPAHMLLAGILLKMGGYALIRMNAGILPDAHAYFAPVLVVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVIIGFASFTDLGLSGAVLQMVSHGLIGASLFFLVGATYDRTHTLMLDEMGGVGKRMPKIFAMFTACSMASLALPGMSGFVAELMVFVGFATSDAYSSTFKVIVVFLMAVGVILTPIYLLSMLREIFYGKENEELVSHQQLIDAEPREVFVIACLLVPIIGIGFYPKLLTQMYDATTVQLTARLRDSVPTLAQEKQEVARVSLSAPVIGN
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4-2, NAD(P)H dehydrogenase I, subunit D-2, NDH-1, chain 4-2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi- pass membrane protein.
Protein: TRDMT_HUMAN
Sequence: MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPPCQPFTRIGRQGDMTDSRTNSFLHILDILPRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAKLIKILYE
What is the function of this protein?
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
What are the official names of this protein?
tRNA (cytosine(38)-C(5))-methyltransferase, DNA (cytosine-5)-methyltransferase-like protein 2, Dnmt2, DNA methyltransferase homolog HsaIIP, DNA MTase homolog HsaIIP, M.HsaIIP, PuMet.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAB_SALPA
Sequence: MTFRHCVAVDLGASSGRVMLARYDSKHRTLTLREIHRFVNCLQKTDGFDTWDIDSLEKDIRLGLKKVCNEGILIDSIGIDTWGVDYVLLDKQGQRVGLPVSYRDNRTTGIMPQALVQIGKSEIYRRSGIQFLPFNTIYQLRALTKQQPELTAQVAHALLMPDYFSYRLTGEMNWEYTNATTTQLVNINTDDWDDTLLAWTGAKKSWFGRPSHPGNVIGDWICPQGNRIPVVAVASHDTASAVIASPLANKHSAYLSSGTWSLMGFESKKPYTTDEALAANITNEGGAEGRYRVLKNIMGLWLLQRVLKERRITDLPALIAQTEALPACRFLINPNDDRFINPDDMHAEIQAACRETDQPVPVSDAELARCIFDSLALLYADILHELANLRGEKFTQLHIVGGGCQNALLNQLCADACGIRVMAGPVEASTLGNIGIQLMTLDELNNIDDFRQVVSANYDLTTYIPNPDSEIARHVAQFQPKRQTKELCA
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: H13C1_CYRHA
Sequence: MKTAIFTVVLALAVFAVLSFGWEANEKALSEEFTELIHEKEAASETEARECRYFWGECHDHMPCCDWLVCRYKWPITYNICVWSRTFPEK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U7-theraphotoxin-Hhn1c, U7-TRTX-Hhn1c, Hainantoxin-XIII-3, HNTX-XIII-3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 13 (Hntx-13) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NTXA_DENEC
Sequence: MRFALVAAITIALLVAGSVADESSEDIDNIVIKTPLDLPRCDSPFCSLFRIGLCGDKCTCVPLPIFGLCVPDV
What is the function of this protein?
Neurotoxin certainly responsible of defensive persistent and painful stings of the giant stinging tree, since it provokes similar effects (PubMed:32938666).  Acts by potently delaying voltage-gated sodium channel (Nav) inactivation in a concentration-dependent manner (EC(50)=58 nM) (PubMed:32938666).  Mainly targets Nav1. 7/SCN9A channels, since the two Nav1. 7/SCN9A inhibitors tetrodotoxin and the spider toxin Pn3a potently reduce nocifensive behaviors it causes (PubMed:32938666).  On the Nav1. 7/SCN9A channel, this toxin causes a significant hyperpolarizing shift in the voltage dependence of activation, but has no significant effect on the voltage dependence of steady-state fast inactivation (PubMed:32938666).  Its effects on Nav currents are irreversible, with no apparent reduction in activity even after repeated wash steps over 30 minutes (PubMed:32938666).  In vivo, it causes nocifensive behavior in mice (licking or biting and shaking or lifting of the affected paw) lasting for approximately 1 hour (PubMed:32938666).
What are the official names of this protein?
Excelsatoxin A, ExTxA.
What is the protein family that this protein belongs to?
Belongs to the gympietide family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURB2_BACCR
Sequence: MNMQEVYKYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANEYNIPVTFLGNGSNVIIKDGGIRGITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLTGLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGDGELRTLTKEAFEFGYRKSVFANNHYIILEARFELEEGVHEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLIQDSGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRIIGEDKE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase 2, UDP-N-acetylmuramate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPG_PENCH
Sequence: MADLVDHSPHHATKAAKLASASNVILIDNYDSFTWNIYQYLVLEGATVTVYRNDEVTVEDLVAKKPTQLVISPGPGHPDTDAGISNAVIKHFSGKVPIFGVCMGQQCMITSFGGKVDVTGEILHGKTSELKHDSKGVYQGLPTSLEVTRYHSLAGTHSTIPDCLEVTSRVELGDASGKNIIMGVRHKEFAVEGVQFHPESILTQYGRKMFRNFLELTAGTWDNKQGAAVAAPADKKLSILDKIYAHRKNAVDEQKKIPALRPEALQAAYDLNIAPPQLSFPDRLRQSDYPLSLMAEIKRASPSKGIISANVCAPAQAREYAKAGASVISVLTEPEWFKGTIDDLRAVRQSLEGLPNRPAVLRKEFVFEEYQILEARLAGADTVLLIVKMLDIELLTRLYHYSRSLGMEPLVEVNTPEEMKIAVDLGSEVIGVNNRDLTSFEVDLGTTSRLMDQVPESTIVCALSGISGPQDVEAYKKEGVKAILVGEALMRAPDTSAFVAQLLGGSNQNFAGASPSSPLVKICGTRTEEGALAAIQAGADLIGIIMVQGRSRLVPDDVALGISRVVKSTPRPADTLQQPSSATSLEWFDHSTNILRHPSRALLVGVFMNQPLSYVVSQQQKLGLDVVQLHGSEPLEWSSLIPVPVIRKFAPGDIGIARRAYHTLPLLDSGAGGSGELLEESGVKKVLDSDEGLRVILAGGLNPDNVAGTVKKLGQSGQKVVGLDVSSGVETNGAQDLEKIRAFVKSAKSIRQ
What is the function of this protein?
Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
What are the official names of this protein?
Multifunctional tryptophan biosynthesis protein.
Protein: UREG_PROMM
Sequence: MSSKLRLGVAGPVGSGKTALVEAMCRRLRDQLQLAVVTNDIYTQEDAEFLTRVGALEPERIRGVETGGCPHTAIREDCSINRAAVEDLERNFPDLDVVLVESGGDNLAASFSPELVDLCIYVIDVAAGDKIPRKGGPGITRSDLLVINKIDLAVHVGADLEVMKRDTTRMRGERPWCFTNLRSGDGLESVLHFLLQQLPNRP
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_STRSY
Sequence: MKQSKMIIPTLREMPSDASVISHALMLRAGYVRQISAGIYSYLPLANRVIEKAKNIMREEFDKIDAIEFLAPALLSADIWRESGRYETYGDDLYKLKNREGSDFILGPTHEETVTLLARDAVQSYKQLPLNIYQIQPKYRDEKRPRNGLLRGREFIMKDGYSFHASYESLDQTYDDYKAAYEAIFTRAGLEFKAIIGDGGAMGGKDSQEFMAITPDRTDLDRWVVLDKSVASFEEIPEDVLEAFKAELLAWSVSGEDTIAYSSESGYAANLEMATSEYKPSTAVVVEEDLVKVATPDAKTIDEVAAFLNVAEEQTIKTMLFMADGEPVVALLVGNDQVNDVKLKNHLAADFFDVASPADAEKVFGAGFGSLGPVGLPENIKIIADRKVQDVKNAVVGANEDGFHYTGANAGRDFQVTEYVDIREVKEGEPSPDGHGVLNFARGIEIGHIFKLGTRYSDSMNANILDENGRSMPIIMGCYGIGVSRLLSAVLEQHARLFVNKTPKGEYRYAWGINFPKELAPFDVHLIPVNVKDEAAMELTQSIEASLVGAGYEVLTDDRNERVGVKFSDSDLIGLPIRVTVGKKAADGIVEVKIKGTGDTVEVHVDQLLETLQILTKENE
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK2_SHEON
Sequence: MRIAILSQGPELYSTKRLVEAATLRGHEVKVINPLECYMNINMRQSSIHIGGEELPPFDAVIPRIGASITFYGSAVLRQFEMMGVYALNDSVGISRSRDKLRSMQLMSRRGIGLPITGFANKPSDIPDLIDMVGGAPLVIKLLEGTQGIGVVLAETRKAAESVIEAFMGLKANIMVQEYIKEANGADIRCFVLGDKVVAAMKRQAMPGEFRSNLHRGGTASLVKLTPEERSVAIRAAKTMGLNVAGVDLLRSNHGPLVMEVNSSPGLEGIEGATAKDVAGAIIEFVEKNALKTKKPTQA
What are the official names of this protein?
Probable alpha-L-glutamate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: Y1315_STRPC
Sequence: MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDHTLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYIDYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFSKAYITIWYKRYLELKNR
What are the official names of this protein?
UPF0374 protein MGAS9429_Spy1315.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: P33_MALP2
Sequence: MKIKKIKLLKALALTGAFGIVATVPVIVSSCSSTDNNGGTGDNNTGGGGSGTDQQQGTTYTPAIKSDVTLSGALSKIYDTTNTGDSRKNTNTLIAEDIKANPENYFTNGEDLKKVEGWSVTVDGSFDSNSVWTGDAYSKWSAVADTHKGVYKSTSKQLNINSLKDLKSQLDTSAKIKAICDESNLVFSTADADSYKIQNELGFTGGDLLHINVTATQAGKTLNMDLGIPVSDLNLKITDLKVSVTASNNSTGNNVAAVSDLTTNFTYNIGIKEEVTAPTEKPNLAKTDKGEVMKVLKALGYTQTGDETKLDNDKVSNSLGLYNCEFTAVSATPVEGSEDKFTIKLKAKPLTDYVWEDGTNTEKEISFEATFTMTGN
What are the official names of this protein?
Lipoprotein p33.
What is the protein family that this protein belongs to?
Belongs to the p35 lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: L_BCCV
Sequence: MEKYREIHQRVREIAPGTGSALDCMDLLDRLYAVRHDLVDQMIKHDWSDNKDVETPIGQVLLMAGVPNDIIQGMEKKIIPNSPTGQILKSFFKMTPDNFKITGNQIEFIEVTVTADVARGIREKRLKYESGLRFTEELLELEVKKGNLQQVYRISFNVVAVKTDGSNISTQWPSRRNEGVVQQMRLVQADINYVREHLIMQDERASLEAMFNLKFHVTGPRLRYFSIPDYRPQPLCNPTIDGLLQYCKQWLTEEHKFIFKEVSGTNVMGSFEVNEKKHKERYLESRKPRNFLLLQTTIQGSYLPSTISSDQCNTRIGCLEICKNIPETPVQALASDIAFKYISLDKDEVINYYNPRIHFKPGQNVKEPGTLKIGLSQMNPLSKAILDNIGKHKSDKGLFGQAIESINIASQIQLNECSKVIEQILSNLEINISDVSENIPLPKKTTCVDELLGKFYENEITKYMLGILRKTVAWHIGHLIRDITESLIAHSGLRRSKYWSVHAYDHGNVILFILPSKSLEVAGSYIRFFTVFKDGIGLVDNDNTDSKTEIDGITWIYSKVMSIDLNRLLALNIAFEKALLATATWFQYYTEDQGHFPLQHALRSVFSFHLLLCVSQKMKICAIFDNLRYLIPSVTSLYSGYELLIEKFFERPFKSALDVYLYSIIKSLLVSLAQNNKVRFYSKVRLLGLTVDQSTVGASGVYPSLMSRVVYKHYRSLISEATTCFFLFEKGLHGNLTEEAKIHLETVEWARKFNEKENRYGDILMKEGYTIELVENQNVTVEQQLFCQEVVELSAMELNKYLHAKSQVLCANIMNKHWDKPYFSQVRNISLKGMSGSLQEDGHLASSVTLIEAIRFLNSSQINPNVIDMYERTKHCKAQARIVRKYQRTEADRGFFITTLPTRVRLEIIEDYYDAIAKVVPEEYISYGGERKILNIQSALEKALRWASGISEIITSTGKKIRFKRKLMYVSADATKWSPGDNSAKFRRFTQAIYDGLNDDKLKCCVVDSLKNIYETEFFMSRKLHRYIDSMESKSEAVEDFLSFFSGGVSATVKGNWLQGNLNKCSSLFGVAVSLLFKRVWVELFPELECFFEFAHHSDDALFIYGYLEPEDDGTDWFMYVSQQIQAGHYHWHAVNQEMWKSMFNLHEQLLLMGSIRVSPKKTTVSPTNAEFLSTFFEGCAVSIPFIKILLGSLSDLPGLGFFDDLAASQSRCVKALDLGACPQLAQLAIVLCTSKVERLYGTADGMINSPISFLKVNKAHIPIALGGDGSMSIMELATAGIGMADKNILKKAFYSYKHTKRDGDRYILGLFKFLMSLSDDVFQHDRLGEFSFVGKVQWKVFTPKSEFEFYDQYSMTYLQAWSKQHPVYDYIIPRGRDNLLVYLVRKLNDPSIITAMTMQSPLQLRFRMQAKQHMKVCKLEGEWVTFREILAAADSFASTYQPNEKDLDLFNTLVSCTFSKEYAWKDFLNEVRCEVTTARHVHRPKVARTFTVREKDQVIQNPITSVIGYKYASTVDEISDVLDSAFFPDSLSADLQVMKEGVYRELGLDIGLPEVLKRIAPLLYKAGKSRIVIVEGNIEGTAESICSYWLKNMSLIKTIKVKPRKEVLKAVSLYGTKDNLSLQDDLAATRICIEVWRWCKANNQNVQEWFTALYFENQTLYDWIERFRRKGVVPVDPEIQCMALLLYDVLGFKNVLQMQANRRAYSGKQYDAYCVQTYNEETKLYEGDLRVTFNFGLDCARLEVFWDKKEYVLETSITQKHVLRLMMEEVSKELVRCGMRFKTEQVSHTRSLVLFKTESGFEWGKPNIPCIVYKHCALRTGLRTKHPINKEFMINIQSDGFRAIAQMDIESPRFLLAHAYHTLRDVRYQAVQAVGNVWFRTEQHKLFINPIISSGLLENFMKGLPAAIPPAAYSLIMNKAKISVDLFMFNELLALINKNNILDLSGIEETSEGYSTVTSMSSKQWSEEMSLMSDDDIDDDEEFTIALDDIDFEQVDLEEDIQHFLQDESAYVGDLLIQTEEVEVKRIRGVTRILEPVKLIKSWVSKGLAIDKVYNPVGILLMARYMSKNYDFHSVPLALMNPYDLTEFESVVKGWGETINDRFQEIDLEAQRLVREQNIQPEDILPDSLFSFRHVDVLLKRLFPRDPISSFY
What is the function of this protein?
RNA-dependent RNA polymerase, which is responsible for the replication and transcription of the viral RNA genome using antigenomic RNA as an intermediate (By similarity).  During transcription, synthesizes subgenomic RNAs and assures their capping by a cap-snatching mechanism, which involves the endonuclease activity cleaving the host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral transcription.  Cleaves ssRNA substrates but not DNA (By similarity).  Seems to downregulate the expression of its own and heterologous mRNAs through its endonuclease activity (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the Bunyavirales RNA polymerase family.
What are the subcellular locations of this protein?
Host cytoplasm, host perinuclear region.
Protein: PDXB_SERP5
Sequence: MKILVDENMPYATELFSRLGNVQAVPGRPIPSDALADADALMVRSVTKVNEALLAGTRIGFVGTATAGTDHVDDVWLQQQGIGFSAAPGCNAIAVVEYVFSALMLLAERDGFQLRDKTVGIIGVGNVGSRLDARLKALGVRTLLCDPPRAERGDAGEFWPLEKLVAEADVLTFHTPLNKSGPYNSLHLVDAELLAALPDNRILINACRGAVVDNAALLQALEKGKKLSTVLDVWEPEPELSLPLLARVDIGTAHIAGYTLEGKARGTTQVFEAFSRHLGQPQQIELASLLPVPEFSQIQLNGPLDEGKLKRLMHLVYDVRRDDAPLRKVAGQPGEFDRLRKHYQERREWSSLRVQCDDSASAELLHKLGFLTA
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS82_METCA
Sequence: MSITTLAVPGVRGLTPYQPGKPIGELEREFALKRIVKLASNENPLGASPKVLEVVRRILGGTHLYPDGSGFELKAALAEKLGVEPAQIVLGNGSNDVLDLVARAFLTAGRNAVYSEYAFAVYPIATQTAGATGKTAPAHDGSRGPRFGHDLETMLERVDPDTRVVFIANPNNPTGTLLGRGELYSFLAALPEHVIAVVDEAYFEYARRPDHPDALEWLGEFPGLIVTRTFSKAYGLAGLRVGYAVTGVEIADLLNRARQPFNVNTLGLAAAAAALEDTGFLEATVQANDAGRSQLEAGFRERGFDFIPSAGNFVSFDLGRPATPVFDALLREGVIVRPLGNYGLPNHLRVSVGTAEEIDLFFAALDRVLVP
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: KATG_XYLFT
Sequence: MRDMRASSPETTSAVKCPFNKTAVEGTHNKDWWPNQLRVDLLHQHSNKSNPLGETFDYAKEFQKLDYAALKRDLHALMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRIGDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKKKYGQQISWADLIVLAGNVALESMGFKTFGFAGGRVDTWEPDQDVYWGREMTWLGGDVRYGAVSEGVHHPDEHRGAKEKASKNSDSRVLENPLAAVQMGLIYVNPEGPDGCPDPLASARDIRETFARMAMNDEETVALIAGGHTFGKTHGAAPADNVGPEPEAGELEQQGLGWHNRFGSGKAGDTITSGLEVTWTKTPTQWSNDFFEHLFGYEWELTKSPAGAYQWVAKDAAATIPHAHDPSKKLLPMMLTSDLALRFDPVYEKISRHFHAHPDQFADAFARAWFKLTHRDMGPRVRYLGPEVPAEELIWQDPVPKVSHVLVDAQDLLALKHKISASGLGISQLVSTAWASASTFRGSDKRGGANGGRLCLAPQSQWEVNQPQQLSVVLETLRRVQAEFNAQAGDKRISLADLIVLAGGVGVEQAAKRAGIVLEVPFVPGRTDALQEQTDVSSFAPLEPFADGFRNYVKEGCVVPSEHLLIDRAQLLTLTAPEMTVLIGGLRVLGANVGGVKHGVFTDRLGTLSNDFFINLLDMGTEWAPVSKERHLFEGRDRRTGALKWTGTRVDLVFGSNSLLRALAEVYAAVDAQEKFVRDFVAAWSKVMHLDRFDLV
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: AROC_XANOM
Sequence: MSANAFGKLFTVTTFGESHGPAIGCVVDGCPPGLEIAPEEFSHDLQRRASGKSRHTSARREADEIEILSGVYEGRTTGTPIGLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLGEIRPAGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVLAGGVPAGWGEPIYGKLDAELAAALMSINAVKGVEIGDGFASAAQKGTEHRDLITPEGFRSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGSVVDVITTGRHDPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEISPRIPGQVDV
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PYRE_CLOBM
Sequence: MSNINVIDILKESDALLEGHFLLSSGRHSNRYCQCAKLLQCPQKAEKVISVIAEKLKEVDFNIIVGPAMGGVIVSYELARQTNKPGIFAERKEGVMCIRRGFEIKKGDKVIISEDVVTTGKSSLEVAKVIEEMGGEVVGIACIVDRRAEDVKTNYPIYSACKLEIETYEKDNCELCKKNIPFVKPGSREQK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RL20_AERHH
Sequence: MPRVKRGVTARARHKKVMKAAKGYYGARSRVYRVAVQAVTKAGQYAYRDRRQKKRQFRQLWIARINAAARQNGLSYSRLINGLKKASIEIDRKILSDIAVHDKLAFTALVEKAKAALV
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ADDB_GEOTN
Sequence: MSLRFLLGRSGSGKTTACLEEIRRQLQEDPKGRTIVYLVPEQMTFQCEYALIHTEGTEGMIRAQVFSFPRLAWRVLQETGGMNRYHVHDVGVQMMIRKIIEQRKQELKLFGRAADKSGFVEQLHEMIAECKRYCLTPDELRRHAGVLESGSGQPGRRLLADKLSDVALVYEELERSLLGHYLDSEDYLRLLVEHIPRSSYLHGADIYIDGFHHFSPQEYMVIEQLLHRCRRVTVCLTADRPYDVGMPDELDLFYLPAQTYRQLRELALANDIMIESPVVLSVNRRHQDKALAHLEEQFHRRPLLPYEAETDAICLYEAANRRAEIEAVAREIIRLVRDEGARYRDIALIIRQTEAYRDLVKTVFFDFDIPYFMDEKEPMHYHPLIELVRAALETVVTRWRYEAVFRAVKTDLLFPVDGDLAMWREAADKLENYVLAHGVKGEKWTSDERWTYRRYQALDGLNVPQTDEERQFEDKLNEWREALAAPLRRLERRLRRAADGRGLCTALYLFLEELQIPKKLEQMSAQAEADGRLVEARQHEQAWNAVVDLLDQYVEMLGAEPLPLAEFAKIIEAGLDRLEFALVPPAIDQVIVAQLDRSRLIDVKYAFIIGVNDGVIPAKVKDEGLVAEVEREQLRELGVALAPGGREQLFYDPFFVYLALACPSRRLYVTYPLADGEGKALMPSPLIKQLVQLFPRVSVHLCGNDPFDAPEEKPETFVTVPRATQTYLISQLRAWKRNYGIDPLWWDVYNVLISHPEWRARVEQAVSGLFYTNQAVLKREWSRRLYGKKIQASVSRMEQFQKCPYAHFASHGLRLKERNVFRLEAPDVGQLFHAAIKQIADRVREQHLDWKQLSRSECERLSAEAVERIAPLIQQQVLSSSNRYEYMKRKLKNVVARTTHVLSEHARASGFAPVGFELSFGPGGDLPPLRFQLRDGTVMELVGRIDRVDKAESSQGVLLRIIDYKSSAKTLDLTEVYYGLALQMFTYLDIVLTYAEQLVGEPALPAGVLYFHIHNPIIQAKQWLDNEMEVARKLLEPFRMRGLLLADAETIRLMDSQTENGQWSLIVPAQLTRTGAIHSRSSVASASDFAALRQHVRRLFVDIGGQIADGVVSIAPYKLKNKTACEFCAFKPVCQFDEALSGNGYRKLTPQTKDAVIETLGKREEES
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.