PharMolix/UniProtQA huggingface dataset:
Protein: YCHN_SHIFL
Sequence: MQKIVIVANGAPYGSESLFNSLRLAIALREQESNLDLRLFLMSDAVTAGLRGQKPGEGYNIQQMLEILTAQNVPVKLCKTCTDGRGISTLPLIDGVEIGTLVELAQWTLSADKVLTF
What are the official names of this protein?
Protein YchN.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0989.
Protein: DXS_NOCSJ
Sequence: MGLLDSIASPADLRGLSDAQLEQLASEIRDLLIRTVATNTGHLGPNLGVVELTLAIHRVFDSPRDRVVFDTGHQAYVHKLVCGRAASFGTLRREGGVSGYPSQAESPHDIVENSHASTALSYADGLAKAYTIRGEDRHVIAVIGDGALTGGMAWEALNNIAIAKASKLVIVVNDNGRSYTPTIGGLATALTSLRTNPRYENVLDLVKRRLNAVPGVGPAAYDALHAMKKGLKDALAPQGLFEDLGLKYVGPVDGHDRAAMEQVLAQAKRFNGPVIVHAITRKGYGYDPAERHEADQFHAPGPFDVQTGAEKPKGRIWTDVFSEEIVHLGHRRKDLVGITAAMMHPVGLDAFQKHFPERTFDVGIAEQHAATSAAGLAMGGMHPVVALYGTFLNRAFDQVLMDVALHKCGVTFVLDRSGVTGDDGASHNGMWDMSILQVVPGLRLAAPRDPARLRELLNEAVEVDDAPTVVRFPKGSPPEDIEAVDRAGGADILVRNGTKDVLVVAVGAMGTTAVDVAQRLTAQGIGVTVVDPRWVKPVDPAIVELAREHRLVVSIEDNGETGGCGAVLLQTLNAAGVHTPFRLHGIPQQFLGHAKRAAILERIGLTPQAIALRIVEDMTSLTEGRSPLDVEQAT
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: GCOA_AMYS7
Sequence: MTTTERPDLAWLDEVTMTQLERNPYEVYERLRAEAPLAFVPVLGSYVASTAEVCREVATSPDFEAVITPAGGRTFGHPAIIGVNGDIHADLRSMVEPALQPAEVDRWIDDLVRPIARRYLERFENDGHAELVAQYCEPVSVRSLGDLLGLQEVDSDKLREWFAKLNRSFTNAAVDENGEFANPEGFAEGDQAKAEIRAVVDPLIDKWIEHPDDSAISHWLHDGMPPGQTRDREYIYPTIYVYLLGAMQEPGHGMASTLVGLFSRPEQLEEVVDDPTLIPRAIAEGLRWTSPIWSATARISTKPVTIAGVDLPAGTPVMLSYGSANHDTGKYEAPSQYDLHRPPLPHLAFGAGNHACAGIYFANHVMRIALEELFEAIPNLERDTREGVEFWGWGFRGPTSLHVTWEV
What is the function of this protein?
Part of a two-component P450 system that efficiently O-demethylates diverse aromatic substrates such as guaiacol and a wide variety of lignin-derived monomers.  Is likely involved in lignin degradation, allowing Amycolatopsis sp.  ATCC 39116 to catabolize plant biomass.  GcoA binds and processes the substrate with electrons supplied by the GcoB subunit.
What are the official names of this protein?
Aromatic O-demethylase, cytochrome P450 subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RLMN1_MYXXD
Sequence: MPSDTSANLYDLTRPALGALLSGWGFGPYHRDQLWTALYRRHATTFDELDGLKPELLRMLREHTRLGQLATHHESFSSDGFTHKLLLRLDDGQTIETVLMRFKGRATVCISTQAGCAMGCVFCATGQMGLSRHLTPGEIVGQILHVNRILRASGETLRNVVLMGMGEPLHNYEHTMSAVDVLVDALGLAMGPRFITLSTVGVVPGIRRLADEERPIHLAVSLHGATDAERAALVPAGRRWPLDELMDACRYYSEKRKRRIFFEWTLISGRNDTAEHAHTLGQLLRGMDAHVNVIPLNPTVGYDGGPSRPESVRAFQDVLATYDVPSTVRQRRGIDIDAGCGQLKATVERRSRRSLPTSA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN 1, 23S rRNA (adenine(2503)-C(2))-methyltransferase 1, 23S rRNA m2A2503 methyltransferase 1, Ribosomal RNA large subunit methyltransferase N 1, tRNA (adenine(37)-C(2))-methyltransferase 1, tRNA m2A37 methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_SYNR3
Sequence: MATASPTRTKMRIRKGDTVQVIAGKDKGKTGEVLRTLPWENRVVVQGVNLRTRHVKPAQEGESGRIVTEEASLHASNVMVYSTDKKVASRVEIVVDKDGNKKRKLKKTGELLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: TATC_ARATH
Sequence: MSSTSTSSALIHHFRLTTRNLGSPTKQRCPYAVTFCNSWREAGLRYSVTQRRSKGFGPVSALNDDDSPTETTPGVGSAVEDRPPDSSEDRSSSVYEFLYPRKEELPDDKEMTIFDHLEELRERIFVSVLAVGAAILGCFAFSKDLIVFLEAPVKTQGVRFLQLAPGEFFFTTLKVSGYCGLLLGSPVILYEIIAFVLPGLTRAERRFLGPIVFGSSLLFYAGLAFSYWVLTPAALNFFVNYAEGVVESLWSIDQYFEFVLVLMFSTGLSFQVPVIQLLLGQVGVVSGDQMLSIWRYVVVGAVVAAAVVTPSTDPVTQMLLATPLLGLYLGGAWMVKLTGR
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane.  Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation.  TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TATC, chloroplastic, Protein ALBINO AND PALE GREEN 2, Protein TWIN-ARGININE TRANSLOCATION C, Protein UNFERTILIZED EMBRYO SAC 3.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=The N-terminus is located in the stroma.
Protein: VPS4_DICDI
Sequence: MGDVNFLQKAIQIVQQATEQDNAKNYAEAHRLYIQSLEWFTTALKYEKSERSKATIKAKTLEYLQRAEQLKEYLDKSKNKKPVAVGGNKSNSAGSANGAGKSAKEDDEDMDPEDKKRNDSLSSSIVTTKPNVKWDDVAGLYQAKEYLKEAVIFPIKFPQMFTGNRKPWKGILLYGPPGTGKSYLAKAVATEISSTFFSISPSDIVTKWLGDSEKLVKQLFEMAREKNNSVIFIDEVDSLCSSRNDQESESARRIKTEFLIQMNGVGNDSDGILVLAATNIPWGLDLAIRRRFEKRIYIGLPEPQARAKMFQIHIGSTPNTLVQADYKKLADLTEGYSGSDIGSLVKDAIMQPVRAVQCATHFKQIRAPSREDPSVMTDYVTPCSPGDPLAQEMTWMDIDPTKLKEPEITIADCLKSLRVIKPSVNKADLDRYVEFTNDFGQDGV
What is the function of this protein?
Involved in intracellular protein transport probably out of a prevacuolar endosomal compartment.  May be involved in the release of components of the bilayered coat from the endosomal membrane.  The association with ESCRT-III complex mediates the ATP-dependent disassembly of the ESCRT-III complex (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 4.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Prevacuolar compartment membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: ACPS_YERPE
Sequence: MAILGLGTDIVEISRIQAVVERTGERLARRILSPSEWQHYQQHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVVNDALGKPTLRLHSRAAELAVELGVKSLHVTLADERRYACATVIIES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_RHIEC
Sequence: MGRTPELKLYNTLTREKSAFKPIDAENVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGEDHVTYARNITDVDDKINARALRDHPGLPLNEAIRAVTEKTETQFHADVAELGCLEPSVEPRATDNIAEMIQIIEKLIGNGHAYVAAGEVLFDTKSMADYGELSKRPLDEQQAGARVAVDAHKKNPGDFVLWKLSSHNEPGWESPWGRGRPGWHIECSAMSRRYLGDIFDIHGGGLDLIFPHHENEIAQSRCAHGTEVMANVWMHNGFVQVEGRKMSKSEGNFVTIHDLLHTETFGGRKWPGEVLRLAMLMTHYREPIDFSIKRLEEAERLLAKWPTAEAGDAAPDESVLNALADDLNTVAAVQALHALAQPGNDAVFAASAVLLGVLPKKVEIDEAFAAAVDALVAMRLEVLKAKNFVEADRIRDELGAKGIQLKDGKDPETGERVTTWEVKR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_EDWI9
Sequence: MFTGSIVALVTPMDDKGNVDRASLRKLVDYHVASGTSAIVAVGTTGESATLSHDEHVNVVLQTLELADGRIPVIAGAGANATAEAIALTECFNHCGVVGCLSVTPYYNKPTQEGLYQHFRAIASCTDLPQILYNVPSRTGCDMLPETVARLAQINNIIAIKEATGNLSRVGQIQDLVNDDRFILLSGDDASALDFMCLGGKGVISVTANVAARQMAEMCRLTLAGDVHAARRLNQSLMPLHRDLFIEANPIPVKWATKVLGLIATDTLRLPLTPLSASARPAVERALQHAGVL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_SHIBS
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADSL1_ARATH
Sequence: MGDTTKDDGSSQSKAVRGEKRAFFFRKWTRIDIARASAVGAVHLLCLLAPFNYKWEALRFGVILAIVTSLSITFSYHRNLTHKSFKLPKWLEYPFAYSALFALQGHPIDWVSTHRFHHQFTDSDRDPHSPIEGFWFSHVFWIFDTSYIREKCGGRDNVMDLKQQWFYRFLRNTIGLHILTFWTLVYLWGGLPYLTCGVGVGGTIGYNGTWLINSACHIWGSRAWNTKDTSRNIWWLGPFTMGESWHNNHHAFEASARHGLEWYQVDLTWYLICFFQALGLATDVKLPTDAQKRKLAFAR
What are the official names of this protein?
Delta-9 desaturase-like 1 protein.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ENO_BORDL
Sequence: MGFHIYEIKARQIIDSRGNPTVEADVILEDGTLGRAAVPSGASTGTNEAVELRDGDKSVYMGKGVLKAVENIINIISPELEGMSALNQVEIDRKMLELDGTPNKSKLGANAILAVSMATARAAAEHLGLKVYQYLGTYKANILPTPMCNIINGGAHSDNSVDFQEFMIMPIGAKTFSDAIRMSAEVFHTLKSILSKKGYATSVGDEGGFAPNLKSNEEACEVIMEAIKSAGYTPGTDIAIALDPATSELYDPKTKKYVFKWSTKEELTSQEMVEYWAKWVEKYPIISIEDGMAEEDWDGWKKLTDKIGNKIQLVGDDLFVTNTSFLKKGIEMKVANAILIKVNQIGTLTETFEAVEMAKKAGYTAIVSHRSGETEDTTIADLVVALGTGQIKTGSLSRTDRIAKYNQLLRIEEELGSIAEYHGKDVFYSINK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PAND_ECOK1
Sequence: MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_KOCRD
Sequence: MAGQKIRIRLKSYDHEVIDVSARKIVETVTRAGATVVGPVPLPTEKNVYCVIRSPHKYKDSREHFEMRTHKRLIDIIDPTPKAVDSLMRLDLPADVNIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RS16_BACSU
Sequence: MAVKIRLKRMGAKKSPFYRIVVADSRSPRDGRFIETVGTYNPVAKPAEVKIDEELALKWLQTGAKPSDTVRNLFSSQGIMEKFHNAKQGK
What are the official names of this protein?
30S ribosomal protein S16, BS17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: IF2_VIBPA
Sequence: MTQLTVKALSDEIGTPVDRLIEQLADAGMKKASSDNVTDEEKQKLLSHLKKEHGDKSGDAEPTRLTLQRKTRSTLSVNAGGGKSKNVQVEVRKKRTYVKRSTIEDEAKREAEEVAKREAEEAAKRVAEETAKREAEEAAKREAEDAVKREAEEKAKREAEEKAKRDADTNAQRNAEEKAKRDAEEKIKQEAARKEADELKRRQEEEAKRKAEEESQRKLEEARELAEKNKERWSAAEEKKGDMEDTDYHVTTSQYAREAEDEADRKEEAGRRNKKKKKPSTKDEQARNSGRSQRGGKGGRKGKLAKPTSMQHGFDKSATVAKQDVVIGETIVLSELANKMSVKATEVIKVMMKMGAMATINQVIDQETAQLVAEEMGHKVVLRKENELEEAVLSDRDTNAESVPRAPVVTIMGHVDHGKTSTLDYIRRTHVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTAMRARGAQATDIVVLVVAADDGVMPQTVEAIQHAKAAGVPLIVAVNKIDKEDANPDNVKNELAQYDVIPEEWGGENMFVHISAKQGTNIDGLLEAILLQSEVLELTAVKEGMASGVVVESRLDKGRGPVATVLVQSGTLHKGDIVLCGQEYGRVRAMRDELGQEITEAGPSIPVEILGLSGVPASGDEATVVRDERKAREVANYRAGKFREVKLARQQKSKLENMFSNMTAGEVAELNVVLKADVQGSVEAIADSLLKLSTDEVKVNIVGSGVGGITETDVVLAEASNAIILGFNVRADASARRAVEAAAVDLRYYSIIYQLIDEVKQAMGGMLAPEFKQEIIGLAEVRDVFKSPKLGAIAGCMVTEGLIKRNNPIRVLRDNVVIYEGELESLRRFKDDVQEVKNGYECGIGVKNYNDVRVGDQIEVFEIVEIQRTLD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y035_CHLTR
Sequence: MKRILVYSDRGVSPYYLRHTVRWLKQVAAPFQMEVCRVNGRFLIHEPLWEETTQLLVIPGGADVPYHNVLHGLGTARIDNYVREGGCYLGICAGAYFGCAQFEFLEPTGSLFVAKRDLGFFPGAANGPVYESAFSYTSSSGVLAAPLVFADFPGESFSLFNGGCCFENAEHFPEICIEARYNNLLGKPAAIVSRRLDKGLVVLSGPHIEYLPEFCSLQEDNVIQAREQIAAHSSSLEEYKQFLIHRLLSNVVEHVLY
What are the official names of this protein?
Uncharacterized protein CT_035.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0128/CT_035/TC_0305 family.
Protein: ATP6_RICCK
Sequence: MTLNPLVQFDIKKLIEIKIFGFDISFTNSSIYMLLASILALTYFYLAFYNWKLVPSRLQVSAEIVYNLVADMLNQNIGAKGHKFIPLFFSLFIFILFCNLLGMTPYSFTVTSHIIVTFALAILVFLTITIVGFVKHSLRFLTLFLPHGTPLWLAPLMIVIELFTYLARPISLSLRLAANMMAGHVLLKVIASFTISLMIYLKFISIPLMVILIGFEIFIAVLQAYIFTILSCMYLNDAINLH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL20_CLOTE
Sequence: MARVKRAMNARKKHKKILKLSKGYFGGKSRLFKTANESVIRALRNAYTGRKLKKRDYRKLWIARINAATRANGLSYSRFMNGLKLAGIDMNRKMLSEIAINDPKAFSELVEAAKKQLNA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: LELP1_BOVIN
Sequence: MSSDDKNKPGEPKNEPKQCDPGCEQKCETKCQPSCLKRLLQRCSEKCQPPKCPPPKCTPCPPCPPSCPPPPKCPPPCPPPCPPPCPPPCPPKPCVKSCPPKCPPPCPPPE
What are the official names of this protein?
Late cornified envelope-like proline-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
Protein: 042R_IIV6
Sequence: MATLQQAQQQNNQLTQQNNQLTQQNNQLTQRVNELTRFLEDANRKIQIKENVIKSSEAENRKNLAEINRLHSENHRLIQQSTRTICQKCSMRSN
What are the official names of this protein?
Uncharacterized protein 042R.
Protein: ACTB_CRIGR
Sequence: MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQEMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells.  Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction.  In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.  Part of the ACTR1A/ACTB filament around which the dynactin complex is built.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
Actin, cytoplasmic 1, Beta-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: NAGS_CRYNB
Sequence: MLTGSSGKAFILSILQASPSARDSRSYLSSFAPPQPVDIATATPAATPSDGAQPPAQNPLVNALLNPILRRPALVKIQGPFTDAQLESICRGMAHLQKLGLVSVIVVDRDDLPSTESSDRYEAQRQRAIVRHEVERVVHFLSRHRAAARPVFSTVARIADPELEPEEAQKGVFVEEEGLDHVRRAVGEGEIPVLLPVALDSGCRSRRIPANRVLLALASAMSTHTSSPVDLTPRRLLVINREGGIPSYARQGLPHLYINLASEFSYINRTFQPQWNDSHPTALSNLFLANGCLAHMPREASALIVSHRSPAALIANLITNKPAHSASLPHALLVESEGRITRDTPTLIRKGLPVRVLRSMEEVDQDKLTHLLETSFKRTLDREGFYNRLKNDLDFVIVIGDYAGAAVCTLEGKPVSDSFAYPPNHPEPICYLDKFAVHPSHQGDGTVDFLWVALRDETYGLGQLDASNPSIGSLRGVGRGRDLVWRSRSDNPVNKWYYERSSGFLKTRDEKWKVFWCDAEQRLGEIWREREFGGGRLVRVVEKEEKGRVKWWEEVIGAIPSAWSA
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: COXX_MYCSK
Sequence: MSIRERHLSHGAPSRIRTTVLAYLALTKPRVIELLLVTAIPAMLLADRGSVDPLLILNTLIGGMLAAAGANTLNCVADADIDKKMKRTARRPLARDTVPTRNALIFGLVLSVGSFFWLWGTSNLLSGLLAVATIAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTRQILIYTWLTVLTTLALALATGWLYASVAVLAGTWFLVMAHQLYNGVKRGEPVKPLRLFLQSNNYLAVVFAALAVDSVLALPTLLGS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1602_METBF
Sequence: MISMKKYDVVIIGAGPAGSYAAYMLAKSKINVLVIDKYSFPRYKPCAGGLTAKAFNSFDFPISKEVKYSTNSIVTSYKNQIFHNISGNKTLVKMIERKEFDDFLIKKAVDSGATFLDGMKVTEITWENAEFSIKTDSEFFRCNYLIGADGTNGIVNRTFNIVERDLYGFAVEINCPVSRDNIGKFNMTFDFGTVPNGYLWIFPKDEYVCVGAYTTNRKMKNIQKYLLDYIEKLGLVPESEKLKGHIIPYYGINYKQPDFPCVLVGDAAGFGEYWTGEGIYYAVKSGTIAAEVISSSIKSGIFDRQALQRRYQREIIRGLKLAYYIGKFFYGNLPLSFNLVMSYLPVGIMYESASRGLTFDQSFSKIHVALSSLILNKSHISNNKYHR
What are the official names of this protein?
Uncharacterized protein Mbar_A1602, ORF3.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. ChlP subfamily.
Protein: VP3_CAV26
Sequence: MNALQEDTPPGPSTVFRPPTSSRPLETPHCEIRIGIAGITITLSLCGCANARAPTLRSATADSSESTGFKNAPDLRTDQPKPPSKKRSCDPSEYRVSELKENLITTTPSRPRTARRCIRL
What is the function of this protein?
May act as transcriptional regulator.  Induces apoptosis in infected cells.  Element of infectious replication cycle.
What are the official names of this protein?
Apoptin.
What is the protein family that this protein belongs to?
Belongs to the gyrovirus apoptin family.
What are the subcellular locations of this protein?
Host nucleus. Note=Host nucleus of infected cells.
Protein: RNP1_METMA
Sequence: MRSKVEILPSTLIFHELIGLEIKVSNSTNPSLIGIRGRVINETKNMLVVENSESRELKIPKADSEFVFRIPAELSEKGRRSDIFVKIQGNLLLSQPENRIKNIKKLRKWG
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_BRASO
Sequence: MIRATRVLGQHRWKEAAADSVLLDFDDRHRRRLAMTGTRGLEFLLDLEHATALRGGDALVLEDGRLIEVVAAAEPLLEIRAGDPHHLVRLAWHLGNRHLPTQIMAKSLRIRRDHVIEAMVKGLGARVIEIEAPFDPEGGAYAEPSHAHGDHDHDHHGHDHHGHDHTSHDHAHHSHAHHDHDHGHAHDDHVHDEHCGHDHHHGHSHAHDHK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2641_SINMW
Sequence: MAGHSQFKNIMHRKGRQDAVRSKMFSKLAREITVAAKAGLPDPAMNPRLRLAIQNAKAQSMPKDNIERAVKKAAGGDAETYEEVRYEGYGPAGVAVIVEALTDNRNRTASNVRSIFTKAGGALGETGSVSFSFDRVGEITYKLSVGDADTVMEAAIEAGADDVETDEEGHTITCGFEDIGEVSKALEGALGEAETVKAVWKPQNTVPVDEEKAQSLMKLIDNLEDDDDVQNVYSNFEVSEEVLAKLSA
What are the official names of this protein?
Probable transcriptional regulatory protein Smed_2641.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_PSEPK
Sequence: MQLNVNDAQAIEVSELTFGGEFNETLVHQAVVAYMAGGRQGTKQQKTRSDVAGGGKRPWRQKGTGRARAGTTRGPIWRGGGVTFAARPQDHSQKLNKKMYRAALRSILAELVRSDRLVVVQDFAVEAPKTKDLLNKLNGMGLSDVLIVSDAVDQNLYLAARNLPHVDVRDVQGSDPVSLIAYEKVLITVSAVKKFEELLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: TYSY_VIBC3
Sequence: MKQYLDLCQRIVDQGVWVENERTGKRCLTVINADLTYDVGNNQFPLVTTRKSFWKAAVAELLGYIRGYDNAADFRQLGTKTWDANANLNQAWLNNPYRKGEDDMGRVYGVQGRAWAKPDGGHIDQLKKIVDDLSRGVDDRGEILNFYNPGEFHMGCLRPCMYSHHFSLLGDTLYLNSTQRSCDVPLGLNFNMVQVYVFLALMAQITGKKPGLAYHKIVNAHIYQDQLELMRDVQLKREPFPAPQFHINPKIKTLQDLETWVTLDDFDVTGYQFHDPIQYPFSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.