PharMolix/UniProtQA huggingface dataset:
Protein: PEX21_YEAST
Sequence: MPSVCHTSPIEKIIQQGHRIQNDSLIPSKRTKLAHTELTAHYATEDSHVEKHFLHNGSNFDGIDNVRYQNQPSPLTFITPNNTVDSSDWVPQFSSMKIDDSLEFSSEYKRLYSNYESQQRLNSSRQHLPFKNCMIRKTSCTYPPQKTLRQQRQGNRDNPTDAFQFDAEFQVLEREIQKERYEPITRRDEKWFDQDQSELQRIATDIVKCCTPPPSSASSSSTLSSSVESKLSESKFIQLMRNISSGDVTLKKNADGNSASELFSSNNGELVGNRHIFVKDEIHKDILD
What is the function of this protein?
Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal via its interaction with PEX7 (PubMed:12167700, PubMed:9864360, PubMed:23812376).  Interaction with PEX7 only takes place when PEX7 is associated with cargo proteins containing a PTS2 peroxisomal targeting signal (By similarity).  PEX7 along with PTS2-containing cargo proteins are then translocated through the PEX13-PEX14 docking complex together with PEX21 (PubMed:23812376).  Acts as an activator of the seryl-tRNA synthetase SES1 by increasing its binding to tRNA (PubMed:12204379, PubMed:17451428).
What are the official names of this protein?
Peroxisomal protein PEX21, Peroxin-21.
What is the protein family that this protein belongs to?
Belongs to the peroxin-21 family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FUMH_MACFA
Sequence: MYRALWLLARSRRLVRPPASALASAPGLSGAAVPSFWPPNAARMASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAVTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK
What is the function of this protein?
Catalyzes the dehydration of L-malate to fumarate.  Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism (By similarity).  Also plays a role in DNA repair by promoting non-homologous end-joining (NHEJ).  In response to DNA damage and phosphorylation by PRKDC, translocates to the nucleus and accumulates at DNA double-strand breaks (DSBs): acts by catalyzing formation of fumarate, an inhibitor of KDM2B histone demethylase activity, resulting in enhanced dimethylation of histone H3 'Lys-36' (H3K36me2) (By similarity).
What are the official names of this protein?
Fumarate hydratase, mitochondrial, Fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm, cytosol. Nucleus. Chromosome. Note=Translocates to the nucleus in response to DNA damage: localizes to DNA double-strand breaks (DSBs) following phosphorylation by PRKDC.
Protein: HIS6_RHOJR
Sequence: MTLAVRVIPCLDVDAGRVVKGVNFENLRDAGDPVELAAAYDAQGADELTFLDVTASTADRGTMLDVVSRTAEQVFIPLTVGGGVRTVEDVDRLLRAGADKVSVNTAAIARPELLRELSERFGSQCIVLSVDARTVPQGQPDTPSGWEVTTHGGKRGTGIDAVEWAVRGAELGVGEILLNSMDADGTKAGFDLPMIRAVRAAVHVPVIASGGAGAVEHFAPAVGAGADAVLAASVFHFGDMTIGDVKKSMREEGITVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_LEPCP
Sequence: MSHPNLLVELFVEELPPKALKKLGESFAGTLAASLKAGGLAGADAVVTPFASPRRLAVHVTGVAAKAADKSVLHKLMPVAVALDAAGNATPALLKKLAALGADASVVPSLKRQPDGKAEALFLDSQVAGATLAEGLQKALDDALAKLPIPKVMGYQLADGWTSVNFVRPAHGLVALHGDDVVPVATLGLVAGRSTHGHRFEAAVPTVELRHADSYAEQLETEGAVIAGFEARRAEIVRQLDAAAAAQGLKPIDDDALLDEVTALVERPNVLVCQFEPEFLAVPQECLILTMKANQKYFPLLDAAGKLTHKFLIVSNIRPDDASAVIGGNERVVRPRLADAKFFFDQDRKKTLESRVPGLARVVYHGKLGTQGERAERVRAIGHAIVNQLRMATIPYTVDAQDEFAVLDSKVQQAALLAKTDLLTDMVGEFPELQGIMGGYYARHEGLRDGVAIAIEDHYKPRFAGDALPRNHTGTVLALADKLETLVGLFGIGQLPTGDRDPFALRRHALGVIRILVEKNLPLDLPALLNGAVPAFGELIEDPRLALFDFMRDRLAVNLRDQGYSAQEVDAVLALEPARLGDVPKRLAAVRAFAALPEAAALAAANKRIGNILKKAEGTVEARIDAALLAEPAEQQLAAALAQVQPGADALFAQGEYAASLQALAALKAPVDAFFDDVMVNAEDPALRANRLGLLATLHGAMNRVAELARLAA
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTD_CROTZ
Sequence: MKLRISDAPFPGAPVMVMISGLGGLGGYWLAQQNALSQAYQVVVYDQRGTGDNADTLPEGYTLTDMAQELHRALALHGVQRYAVLGHALGGLVGLELALAYPRAVSALVIINGWLSLGTWTRRCFDARERLLLDSGPAVYVAAQPLFLYPPQWAQENQPRLEAEEALQNAHFQGTENLLRRLWALKTADYRERAARVTTPVQLICARDDVLVPWTCSQALHEALPHSRLDVMTSGGHACNVTAPQRFNSLLYAGLAALTPAPHKETV
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: DEOD_ECOL6
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGVDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: RS15_NEIG2
Sequence: MALTVEQKAQIVKDFQRKEGDTGSSEVQVALLTFRINDLTPHFKANPKDHHSRRGLLKMVSQRRRLLAYLRRTQPDTYRALITRLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: YCF92_GRATL
Sequence: MNLSQSFLLNRYIQSPRTWLHRLNSNNKIYFLFFYLSIFPYTDVKYMTYSIIFYTILFLYLKHIDKNYKIFILRIVYKVCIFTLAISCLSKLLLSVNIFRLKYISDFFLNLMSICTRNILYIRSVLILTHYFCTVHITFMTTTYEDIIFAFIPLFTQYQNNIIKKVAFISIFALQAIENTLIKIYSILITIKMKQFTKVFKFQYYIYIYLILKFIQDIYNDIYRISTVFYVRELNHKMSYFTYIY
What are the official names of this protein?
Uncharacterized protein ycf92.
What is the protein family that this protein belongs to?
Belongs to the ycf92 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: APT_SALHS
Sequence: MTATAQQLEFLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIELLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPRKLPRETIAETYALEYGTDQLEIHVDAIKPGDNVLVVDDLLATGGTIEATVKLIRRLGGKVTDAAFIINLFDLGGEQRLEKQGITCYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGS4_MOUSE
Sequence: MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHSSSHSKKDKVVTCQRVSQEEVKKWAESLENLIHHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLQPTITCFDEAQKKIFNLMERDSYRRFLKSRFYLDLTNPSSCGAEKQKGAKSSADCTSLVSQCA
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein.  Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 4, RGS4.
Protein: PSAB_TOBAC
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFESWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSAISLIAGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGEYVRWNNFLDVLPHPQGLGPLFTGQWNLYAQNPDSSSHLFGTAQGAGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFIFLVAGHMYRTNFGIGHSMKDLLDAHIPPGGRLGRGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLEHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTSGPAFNAGRSIWLPGWLNAVNENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: STLP5_ORYSJ
Sequence: MARAPPPLSSLPPPPRRPTVVLLLGLALAFCLAVLSIQSSFFTAPRLASRLDLDSDEVRALSGFQSRVQQCVARRGLGLTADIIDHCKLVLRFPKGTNSTWYNTQFKYFEPLEYNYDVCETILLWEQYRNMTTVLTREYLDVRPDGWLDYAAKRIAQLGADKCYNRTLCEELLSVLLPAKPPFHPRQFATCAVVGNSGDLLKTEFGQEIDAHDAVFRDNEAPVNKKYAKYVGLKRDFRLVVRGAARNMAPILKGSSDEVLIIKSLTHKEINAVIKELPNPVYLFQGIVLRRGAKGTGMKSIELALSMCDIIDMYGFTVDPNYTEWTRYFSPPRKGHNPLQGRAYYQLLECLGVIRIHSPMRAKRVEDWSDIPSREEIRTAHAAAFRLKRHETGQSDQMGPFSNCKVWGTVDPDYGPVSGTPDMSETRKSSNYKKWEVLPFDSLRMEAQEHHVQMGGVSLYKMDGNKLDDLVCVRHERSSS
What is the function of this protein?
May possess sialyltransferase-like activity in vitro.
What are the official names of this protein?
Sialyltransferase-like protein 5, OsSTLP5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: LAP1_ASPOR
Sequence: MKIRAALALSATASGVLAAVVPQQALLNNPQIHHENEKYLIELAPYQTRWVTEEEKWALKLDGVNFIDITEERNPGFYPTLHQASNVRYPTKMEHVEEVVGLTHRLTKANMERDLEKFTSFHTRYYKSQTGIESATWLYNQVQTVIEQSGAAEHGATVDRFAHSWGQFSIIARIPGKSNKTVVLGAHQDSINLFLPSILAAPGADDDGSGTVTILEALRGLLQSDTVAQGKAPNTIEFHWYSAEEGGMLGSQAIFSQYKQERRDIKAMLQQDMTGYVQGALNAGRKEAVGIMIDYVDRGLTQFLKDVVTAYCNVGYLETKCGYACSDHTSASKYGYPSAMATEAEMENTNKRIHTTDDRIKYLSFDHMLEHAKLTLGFAYELAFASF
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS1_CHESB
Sequence: MTVTLALPSKGRLKDATVELLREAGYPIRLPENERRYRAGIDGLDGLEVTFLSASEIARELDRGSIDLGVTGEDLVRETIPDWESRVEIAARLGFGHADVVVAVPEIWFDVSTMADLDDVAADFRHRHSRRLRIATKYWRLTQQFFSQKHGIQVYRIVESLGATEGAPAAGSADIIVDITSTGSTLKANHLKVLDDGVILRSQACLVVAKKKRPAEDARLIAELAKAVRR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_PAEAT
Sequence: MLSGLVIVDKPQGWTSHDVVGRMRRLAGTRKVGHAGTLDPMATGVLVLGINKATRLLTYIVGTSKTYTATIRLGETTITDDAEGEVTEARTAAHITDDAVAVGVAALTGPIQQVPSSVSAIKVNGERSYARVRSGEEVKLAARPVTIHRFDVHSITRIDGGRVVDVDVTVECSSGTYIRALARDLGNALGIGGHLTALRRTQVGPYSLDQARTLEELAEELEVLEMSLAARSLMPNRELSEQETTEISFGRRIAAGPGAGTPDAATAEKPAAAFAPSGELVALLADTGSFAKPVLVFAPGTGTGTGTGQAK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RECO_POLSJ
Sequence: MATKRIGDEPAYVLHRYDWSESSLILEIFTRQYGRVALVARGAKKPSSSFRPILLPLQPLHIAFGGDAEIRTLKSAEWQGGHVMPTGDALLSGYYLNELLMRLLARDDPHPVLFDAYSATVQLLASQSVDTLQLALRAFELRLLRDIGLLPLLDAETATLAPLEPQARYVLVAEAGLRQAHDDDRNSLPGVQWQALQQALGDNALFSDTVRACIPGLNELKTQLRALLHYHCGVKVLKTRQMMMDLQAL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RL35_ECO45
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: DMD10_CAEEL
Sequence: MVADVLRQSVLVPISMYPQYPVPRRYTTSVFKEYQKKKKIYYCQRCLNHDVPRPRKNHKCECPYADCTCEKCGLVEKRRILNIRLQNYNQFNIENENDSKLIIVEDDDKKKQGERVPNCQKCGQHGRKSRLKGHKRSCPFRECPCAKCAVVSERQKLMADQIKIRRRQRKDTLLTFAKNSITSTMFPSNQISLNALNSLLYGSINTSPQPLLSSPTSSDASSCSPSMPFTPSIPMFMPTSADCSPTTQTPTSSIPSSIASTSPLMTSLPLRLSGFPLLNIRDPSAEASLLNLGCNADAAALLKTILDQYRMLEEASMSMSSSPSKDDESGDEDSDGLNSNSIIDVITV
What is the function of this protein?
Transcription factor (By similarity).  Plays a role in neuronal signaling in polymodal sensory neuron ASH, downstream of sensory receptor activation (PubMed:33665029).  Required for maintenance of AVG synapses (PubMed:27144354).
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor dmd-10.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DDIT3_HUMAN
Sequence: MAAESLPFSFGTLSSWELEAWYEDLQEVLSSDENGGTYVSPPGNEEEESKIFTTLDPASLAWLTEEEPEPAEVTSTSQSPHSPDSSQSSLAQEEEEEDQGRTRKRKQSGHSPARAGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVEATRRALIDRMVNLHQA
What is the function of this protein?
Multifunctional transcription factor in endoplasmic reticulum (ER) stress response (PubMed:15322075, PubMed:15775988, PubMed:19672300).  Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress (PubMed:15322075, PubMed:15775988).  Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes (By similarity).  Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes (By similarity).  Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L (PubMed:15775988, PubMed:17709599, PubMed:22761832, PubMed:20876114).  Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG) (PubMed:18940792, PubMed:19672300, PubMed:20829347).  Together with ATF4, mediates ER-mediated cell death by promoting expression of genes involved in cellular amino acid metabolic processes, mRNA translation and the unfolded protein response (UPR) in response to ER stress (By similarity).  Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity (PubMed:16434966).  Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response (By similarity).  Acts as a major regulator of postnatal neovascularization through regulation of endothelial nitric oxide synthase (NOS3)-related signaling (By similarity).
What are the official names of this protein?
DNA damage-inducible transcript 3 protein, DDIT-3, C/EBP zeta, C/EBP-homologous protein, CHOP, C/EBP-homologous protein 10, CHOP-10, CCAAT/enhancer-binding protein homologous protein, Growth arrest and DNA damage-inducible protein GADD153.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Present in the cytoplasm under non-stressed conditions and ER stress leads to its nuclear accumulation.
Protein: EREX_ARATH
Sequence: MNLYAHDLSLLDFNYNVSGPFGEPLSHRFLSPGPFFQGEEDDYRRNTSYSHDGANGREPDTDSRASPPHRHDGRSPLPLGMDWSSPPRHLEGRDTVWPHDHRTGWSYCVTVPSWVDLPKSSVSDPAVFYRVQVAIQSPEGITSARLVLRRFNDFLELYSSIKKEFVKKSLPQAPPKKILRMRNQTLLEERRCSLEDWMNRLLSDIDISRSALIATFLELEAAVRSYFNDEYQETEDTSGDIPSLLPTTISDVPGSSSVTIDHDNDSADETSNASTMKHDEANLKNLFSRNSTAVDNVTDWHELITEYGLLDQSSFQEKVERLSSTNGDAATGTVTRGGISSGVGIQRLDGSDRKFQELTIESIKKTHVSDFEASTAVEPDLVNQGAMDIHGEAHGNMYGAVGGDTETQKDLAIVFQSEERHKLKRVIDTLKQRLETAKADTEDLISRLNQELAVRQFLSTKVRDLEVELETTRESCKQGMEKTVLDEKERFTQIQWDMEELRKQCMEMESFLNSIKDEKTHIETANESLVQENQMLLQQINDIRENFENFHKEHEELEVKAKAELKVLVKEVKSLRTTQSDLRQELSGIMKEKLEMERIVQREKDREETAKNADKKLLHECDVLQNRLQECNVKFDIEEEGKLIMDSSSLSEAIELLATSDNRIGLLIAETQLLSEEVEKLKLTSGGHRGTDDLVRKMLTEVLIDNARLRKQVNSVLRCSLSGHGISVREAGTEVDDEEGSIDLARTVMSKILEK
What is the function of this protein?
Acts as an effector of RABF2A and RABF2B.  Involved in vacuolar transport of storage proteins.  Regulates membrane trafficking to protein storage vacuoles (PSVs).  Binds specifically to phosphatidylinositol 3-monophosphate (PtdIns3P).
What are the official names of this protein?
PX domain-containing protein EREX, Protein ENDOSOMAL RAB EFFECTOR WITH PX-DOMAIN.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein. Note=The endosomal localization depends on the active state of RABF2B. Binding of phosphatidylinositol 3-monophosphate via the PX domain is required for the endosomal localization.
Protein: MQO_BURCH
Sequence: MKKGSAVIKTLRVILSALALCVATSSAHAADTKKVDVLLVGGGIMSSTLGVWLHELQPNWSMTMVERLDGVALESSNGWNNAGTGHSALAELNYTPEKADGKVDISKAIEINESFQISRQFWAWQVKQGVLKNPHSFINSTPHMSFVWGDDNVRFLKKRYEALQASPLFRGMQYSEDYDQIKQWVPLMMEGRDRNQKVAATWTPIGTDVNFGEITRQFVGYLKTQPNFTLSLSSEVREITRNADGTWHVSWVKLHSDEPPQSVDAKFVFIGAGGGALHLLQASGIPEAKDYGAFPVGGSFLVTDNPEVVKQHLAKAYGKASVGSPPMSVPHLDTRIIDGKKIILFGPFATFSTKFLKNGSYFDLAKSTNLHNVAPMMRVGVDEFPLVQYLAGQLMLTDDDRFNALKEYFPNAKKEDWRLWQAGQRVQIIKRDPVKGGVLKLGTEIVASQDGSIAGLLGASPGASTAAPIMLNLMQKVFKDKVATPEWQQKIRQIVPSYGTKLNDSPAKVVEEWTYTSDVLQLSPPPKIDLGAPSQATGNAPARPAKASADMAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: PUR7_STRT2
Sequence: MSNQLIYTGKAKDIYSTEDENVIKSVYKDQATMLNGARKETIKGKGVLNNQISSLIFEKLNAAGVATHFIKRISDTEQLNKKVTIIPLEVVLRNVTAGSFSKRFGVEEGLDLKTPIVEFYYKNDDLDDPFINDEHVKFLDIANDEQIAYIKEETRRINELLKDWFEQIGLRLIDFKLEFGFDKDGKIILADEFSPDNCRLWDAEGHHMDKDVFRRDLGSLTDVYEVVLEKLQGLK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: ATPF_STAAS
Sequence: MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLKDVMDKRERDINRDIDDAEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQEQIIHEANVRANGMIETAQSEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQKALVDKYLKEAGDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CLP1_CANGA
Sequence: MAEVEALPGLKQPVDDAGLLEDANQVHTLVIPSGHIWRVELSSDEKLSLKVTAGIGEIFGTELANNVEYTFWDWKFGIYAVEELEIEWKCPQLHDRELSIVENTTAHNVYNLHFALEKMRSSTFDGPRIMVVGEKNTGKTALCRTLCSYAIKNKPYQPMFVNLNPVEPIFSPPGCVTAVPISSTLDAQLPRWGETMTSGATRLHGKQPIIKNFGFETIAENRSLYKLVTKKLFETVSERLQNDSLVHRSGCIVDSPPLENCDDEYSELVEAIVGLRINYLIILCNDNDKGREIYTKVSKIVNTYVGERLLRVPTMAGVFEKDDVYIRAQQRAAIREYFYGDTRTVLSPYNLGCDTSDITVWRPKSVLQGENTNLDTLEVAPVDSSTLQYALVAITYASRKSDSEEVLQAPILGFGLITELNEKRNKLKILLPVPGRLPPNAMILTSFRYLE
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA cleavage and polyadenylation factor CLP1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIQ_SODGM
Sequence: MITLDKVTWLYRHLPLRFDLHVDAGEKVAILGPSGAGKSTLLNLMAGFLTPHSGELWLNGATHNKTPPARRPVSMLFQENNLFAHLTVAENIGLGLHPGLRLTSAQRCQLKDTARQVGLENLLERLPAAISGGQRQRTALARCLVRQQPILLLDEPFSALDPALRAEMVKLLDEVCATRRLTLLMVSHNLDDALRLAPRTLLVVDGRIYYDGPTAALASGESQAAAILGIDC
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.