PharMolix/UniProtQA huggingface dataset:
Protein: RBSD_HAEIN
Sequence: MKKTALLNAQLSHCIATLGHTESLTICDAGLPIPLSVERIDLALTAGVPSFLQTLNVVTNEMYVERVVIAEEIKEKNPEILTALLTQLQKLESHQGNQIQVEFVSHETFKKFTLESKAIVRTGECSPYANVILYSGVPF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_UREPA
Sequence: MANLTKLKIVTPYAQILEKDVYSVELKTSEGRITVLPDHNPLMSTIENHVAYIRELPNTPRKPLLLLDGIVYIEQHQVRVFSDYFKFLDEIQIDEINSSLNQLKHDLNNEEDDKKKLQLKSKIKLNESILIAYKDR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RAPA_SHEB2
Sequence: MPFALGQRWISDTESELGLGTVVQVEGRMVTVLFPATGENRMFSRAEAPLTRVIYNPGDSVESHEGWSLAVSELTEKDGIVIYHGIHSETGEQVTLRETLLNHNIRFNKPQDRLFAGQIDRLDRFGVRYQCQMLRHKLASSDLLGLQGPRVGLIPHQMWIAHEVGRRYAPRVLLADEVGLGKTIEAGLIIHQQLLTGRAERILIIVPDTLRHQWLVEMLRRFNLRFSVFDEDRCVEAYADHDNPFYTEQLVICSLELLRKKKRLDQALDADWDLLVVDEAHHLEWTEEAPSRAYQVVEALSEVIPGVLLLTATPDQLGHESHFARLRLLDPDRFYDYDAFLAEEDSYKDVAIAAEALAGNAKLPDAAINSLTELLGEKDISPSIRLIQADGIDAEVQQAARSELLQELLDRHGTGRVLYRNSRASVKGFPKRFFNAYPHAMPDQYQTAARVSGMMGGHKSLEAKAAQALSPEKLYQEFEDNSASWWKFDPRVDWLIEFLKSHRSKKVLIIASQAETALSLEEALRTREGIQATVFHEGMSIIERDKAGAYFAQEEGGAQALICSEIGSEGRNFQFASHLVLFDLPLNPDLLEQRIGRLDRIGQKNDIQIHLPYLEDTAQERLMQWYHQGLNAFELTCPSGHVLYSEFAEDLLNVLVVDDSDELTNLLNHTQSRYKELKHAMEQGRDKLLEINSHGGEKAMAIVQRLAQNDGDTHLIGSVIRLWDIIGVDQEDKGENSIILRPSEHMMFPTYPGLPEDGVTVTFDRDTALSRDDIALITQEHPLVQTGLDLITGSETGTTSVAILKNKALPAGTLFLELIYMADASAPKSSQLYRYLPPTPIRVLLDKNGNDLSAKVDYASFDKQLSAVNRHIGGKLVTASQPILHPLFAKGEEYAQVVVDEMVAQAREKMTQQLSAELSRLESLKAVNPNIREEELEYLRNQMQELNTYLDASQLQLDAIRMVLVSHV
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: RSMA_THEP1
Sequence: MKTSDYLKKYGVKLKKHLGQVFLSDDRIAKRIVKEVGLTPEDVVVEIGAGAGTLTEELAKTGARVIAYEIDESLAPVLRERLSKYPNVELRFEDFLKAKDIPEGAICVSNIPYSITGPIMEKIIEWKFKRAIVMVQKEVGERILAKPGKKTYGYLSVVVQTFYEVKKLFDVSRSCFVPNPEVDSTVVDLRRKSVDLDFEKFRKFVSMIFAKKRKTLKNNLRPFLSVFEGVDLSRRAEQLTVEEIVEFYEKWRRALECSKE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITN_BACSU
Sequence: MLAILGFVMMIVFMYLIMSNRLSALIALIVVPIVFALISGFGKDLGEMMIQGVTDLAPTGIMLLFAILYFGIMIDSGLFDPLIAKILSFVKGDPLKIAVGTAVLTMTISLDGDGTTTYMITIAAMLPLYKRLGMNRLVLAGIAMLGSGVMNIIPWGGPTARVLASLKLDTSEVFTPLIPAMIAGILWVIAVAYILGKKERKRLGVISIDHAPSSDPEAAPLKRPALQWFNLLLTVALMAALITSLLPLPVLFMTAFAVALMVNYPNVKEQQKRISAHAGNALNVVSMVFAAGIFTGILSGTKMVDAMAHSLVSLIPDAMGPHLPLITAIVSMPFTFFMSNDAFYFGVLPIIAEAASAYGIDAAEIGRASLLGQPVHLLSPLVPSTYLLVGMAGVSFGDHQKFTIKWAVGTTIVMTIAALLIGIISF
What is the function of this protein?
Transports the free citrate anion.  Probably cotransports citrate and at least three or four protons.  The citrate uptake is inhibited by the presence of magnesium ions.
What are the official names of this protein?
Citrate transporter.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RH12_ARATH
Sequence: MNTNRGRYPPGVGTGRGAPPNPDYHQSYRQQQPPQDQQYVQRGYSQNPQQMQLQQQHQQQQQQQQWSRRPQLPGNASNANEVVQQTTQPEASSDANGQDWKATLRLPPPDTRYQTADVTATKGNEFEDYFLKRDLLKGIYEKGFEKPSPIQEESIPIALTGSDILARAKNGTGKTGAFCIPVLEKIDPNNNVIQAMILVPTRELALQTSQVCKELSKYLNIQVMVTTGGTSLRDDIMRLHQPVHLLVGTPGRILDLTKKGVCVLKDCAMLVMDEADKLLSAEFQPSLEELIQFLPQNRQFLMFSATFPVTVKAFKDRHLRKPYVINLMDQLTLMGVTQYYAFVEERQKVHCLNTLFSKLQINQSIIFCNSVNRVELLAKKITELGYSCFYIHAKMVQDHRNRVFHEFRNGACRNLVCTDLFTRGIDIQAVNVVINFDFPRTSESYLHRVGRSGRFGHLGLAVNLVTYEDRFKMYQTEQELGTEIKPIPSNIDQAIYCQ
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 12.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: ALGA_PSESM
Sequence: MIPVILSGGSGSRLWPLSRKQFPKQFLALTGEHTLFQQTLQRLVFEGMQEPIVVCNKDHRFIVNEQLAALNLETQAILMEPFGRNTAPAVALTAMKLVNEGNDGLMLVLPADHVIEDQKALQRALALATVTAERGEMVLFGVPANKPETGYGYIKSTADALLPEGVSRVSQFVEKPDEKRAKEFVEAGGYYWNSGMFLFRASRFLEELKKHDPDIYDTCLLTLERSVQDGDALEIDASTFACCPDNSIDYAVMEKTQRACVVPLSAGWSDVGCWSSLWEVNAKDAHGNVTKGDVVIQDSRNCMIHGNGKLVSVIGLDNIVVVETKDAMMIAHKDKVQGVKQMVATLNEQGRTETQNHLEVYRPWGSYDSVDMGGRFQVKRISVKPGACLSLQMHHHRAEHWIVVSGTAQVTCDENVFLLTENQSTYIPIASVHRLRNPGKIPLEIIEVQSGSYLGEDDIERFEDIYGRSNALEAGVKTQTIAR
What is the function of this protein?
Produces a precursor for alginate polymerization.  The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity).
What are the official names of this protein?
Alginate biosynthesis protein AlgA.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 2 family.
Protein: QUEA_TRIL1
Sequence: MLVKEYSFTLPDELIARYPANQRDGSRLMVLDRQTAARSEIAFSQIVEWLRPDDLLVLNDTKVIPARLFGQKETGGRIELFLVEPVGDACWRCLLRSSKRCRTGQSIRLAEGVTAEVVEQLGEQDWLIRFHGSDDFESWLQRVGQMPIPPYLNRESEELDRVRYQTVYASESGAVAAPTAGLHFTQELLERIQEKGIRLARVTLHVGLGTFQPVRVERVQDHVIHRERYRLPSETAAAVTETRARGGRVIAVGTTACRTLEYAADNAGHLQAGQGEADIFIYPGYRFKVVDALLTNFHLPESTLLMLVSAFGGKEFILSAYEAAVNRQFRFYSYGDAMLIV
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRL_MACMU
Sequence: MNIKGSPWKGSLLLLLVSNLLLCQNVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFDKRYTHGRGFITRAINSCHTSSLPTPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTEVRGMEEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWTGLPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNNNC
What is the function of this protein?
Prolactin acts primarily on the mammary gland by promoting lactation.
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAB_SYNY3
Sequence: MATKFPKFSQDLAQDPTTRRIWYGIATAHDFETHDGMTEENLYQKIFASHFGHIAIIFLWTSGTLFHVAWQGNFEQWIKDPLNIRPIAHAIWDPHFGEGAVNAFTQAGASNPVNIAYSGVYHWFYTIGMTTNQELYSGAVFLLVLASLFLFAGWLHLQPKFRPSLAWFKNAESRLNHHLAGLFGVSSLAWAGHLVHVAIPEARGQHVGWDNFLSTPPHPAGLMPFFTGNWGVYAADPDTAGHIFGTSEGAGTAILTFLGGFHPQTESLWLTDIAHHHLAIAVIFIIAGHMYRTNWGIGHSIKEILNAHKGPLTGAGHTNLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPSYAFIAQDHTTQAALYTHHQYIAGFLMVGAFAHGAIFFVRDYDPVANKDNVLARMLEHKEALISHLSWVSLFLGFHTLGLYVHNDVVVAFGTPEKQILIEPVFAQWIQATSGKALYGFDVLLSNPDSIASTTGAAWLPGWLDAINSGTNSLFLTIGPGDFLVHHAIALGLHTTALILIKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAMFWMLNTLGWLTFYWHWKHLGVWSGNVAQFNENSTYLMGWFRDYLWANSAQLINGYNPYGVNNLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETIVWAHERTPLANLVRWKDKPVALSIVQARLVGLAHFTVGYVLTYAAFLIASTAGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CC049_HUMAN
Sequence: MAQPQLYLPEPFKIAYRKVGQCRRFQQLKKKNGSFKRKGIERWHRAVSTNLLKQNVLVPKEESSSDSDMGFHESQQNQKSNLKTKVKTAFGRMLSYKYRSKPACASQEGSTDHKEALLSNTQSLLPRIVKEFSSPKLFTAKMRKLSENATIQLDVVEAETEEITQGNTLLRARRTTKRLSVTSLPSGLQKGPYSPKKRPHFPALKKKKRGMENILRKSDLTVGKLQMQVDDLIETVTDKSMKLLAQRHAELQQCEFLGDEILQSSKQFQRISKRTMRKYKLKNMTTKGPGDS
What are the official names of this protein?
Putative uncharacterized protein C3orf49.
Protein: IRS4_SCLS1
Sequence: MADPIFNGDASDTKTAKLTRPVTGTSTAARNTQQSAAFENSASVSASTSTLQSTTSSTPRINHNPSINSLRNTHVGGAGTETGRGISAAQNAALTGASLAFSNAKEGRAKARVVPPVPNKGNVQLGEKGLNGNGGALAAAAKAGAVGHNAGGGGRTRSPSKVSAMDEGTVHGQHILGSEKTGESQTTDGGSINGRLEHQIGHTGLQKRKQRSNGHLLPPFSGSGNSMTEHGANMKSSSAAFMAANLAAKRSRESSPSQSHGTGIGIGGGLGKQGSPLMSRRQSYASSIDSLDRRLDVSSIPPTSNLVGMWEQANRGVKKGGAGGGGESSSDRGNEVVSRQESLRRPASSHAPVPVLKPEGLTRPVSSHVPDVELVKSSATKPAVQPPNTSSQASISDEIKSPGKPAVQPQIVYSHTSELEPKKSAAKASVPLRPSSSQDLISEETKSTSKPAVQQRPVSSYTPGSVTLKPSSKSPAQKPVIHNTRPVSSHGPSPNFSAKPSIQKLSRPVSSHSPPPTKPSAKPSSQSIRPISPRAMESTESLSKSPVQKPSIPPSRHTPADAPALNTQSAKPQVQAPRPLSMHSPILKPADRDEPSLKPPVQPPRHSSTKTPPKSPRPKPPFEPPVSKQSYNNNYDDDDGSSDDSFVSASSQPKPKSPSFRAKIAQQKRSQSTSISSMNVNSLANAIVAGSLASSRASTPSISSGTTRAPAPPPTRRHKNLHIFHSDNSRTPTPPHNNGSAAGVPIMKTTMRKPKTGKELKEEEGEGEKRRAKKHLVKKHPNKHNEGNRKRWRDGITERERKRYEAVWASNKGLFPYTINQDGEMVEVDGAVDTVPGIVVRDIWERSRLGEDVLEEVWGLVEGRGYRSRLVANMKAGGRLEKDEFVVGLWLIDQRLKGRKLPGRVGSSVWGSAGPMGGIKIRS
What is the function of this protein?
Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway.  Involved in rDNA silencing (By similarity).
What are the official names of this protein?
Increased rDNA silencing protein 4.
What is the protein family that this protein belongs to?
Belongs to the IRS4 family.
Protein: CKX3_ARATH
Sequence: MASYNLRSQVRLIAITIVIIITLSTPITTNTSPQPWNILSHNEFAGKLTSSSSSVESAATDFGHVTKIFPSAVLIPSSVEDITDLIKLSFDSQLSFPLAARGHGHSHRGQASAKDGVVVNMRSMVNRDRGIKVSRTCLYVDVDAAWLWIEVLNKTLELGLTPVSWTDYLYLTVGGTLSNGGISGQTFRYGPQITNVLEMDVITGKGEIATCSKDMNSDLFFAVLGGLGQFGIITRARIKLEVAPKRAKWLRFLYIDFSEFTRDQERVISKTDGVDFLEGSIMVDHGPPDNWRSTYYPPSDHLRIASMVKRHRVIYCLEVVKYYDETSQYTVNEEMEELSDSLNHVRGFMYEKDVTYMDFLNRVRTGELNLKSKGQWDVPHPWLNLFVPKTQISKFDDGVFKGIILRNNITSGPVLVYPMNRNKWNDRMSAAIPEEDVFYAVGFLRSAGFDNWEAFDQENMEILKFCEDANMGVIQYLPYHSSQEGWVRHFGPRWNIFVERKYKYDPKMILSPGQNIFQKINSS
What is the function of this protein?
Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group (PubMed:14555694).  Catalyzes in vitro the oxidation of various types of cytokinin nucleotides that are known as direct products of cytokinin biosynthesis (PubMed:20825956).  In association with CKX5 regulates the activity of the reproductive meristems, flower organ size and ovule formation (PubMed:21224426).
What are the official names of this protein?
Cytokinin dehydrogenase 3, Cytokinin oxidase 3, AtCKX3, CKO 3.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Vacuole.
Protein: STAR4_HUMAN
Sequence: MEGLSDVASFATKLKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVIDDLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFSYTVGYKEGLLSCGISLDWDEKRPEFVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGMIPQSAVDTAMASTLTNFYGDLRKAL
What is the function of this protein?
Involved in the intracellular transport of cholesterol.  Binds cholesterol or other sterols.
What are the official names of this protein?
StAR-related lipid transfer protein 4, START domain-containing protein 4, StARD4.
Protein: ATAD2_YEAST
Sequence: MARNLRNRRGSDVEDASNAKVGYETQIKDENGIIHTTTRSLRKINYAEIEKVFDFLEDDQVMDKDETPVDVTSDEHHNNNQKGDDEDDDVDLVSPHENARTNEELTNERNLRKRKAHDPEEDDESFHEEDVDDDEEEEEADEFEDEYLDEDSKDNNRRRRAADRKFVVPDPDDDEEYDEDDEEGDRISHSASSKRLKRANSRRTRSSRHPETPPPVRRALRSRTRHSRTSNEENDDENDNSRNEALTLADEIRELQEDSPIREKRFLRERTKPVNYKLPPPLTASNAEEFIDKNNNALSFHNPSPARRGRGGWNASQNSGPTRRLFPTGGPFGGNDVTTIFGKNTNFYNQVPSAFSDNNNNKLILDSDSSDDEILPLGVTPKTKKENTQKKKKKKPEIADLDPLGVDMNVNFDDIGGLDNYIDQLKEMVALPLLYPELYQNFNITPPRGVLFHGPPGTGKTLMARALAASCSSDERKITFFMRKGADILSKWVGEAERQLRLLFEEAKKHQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGMDNRGQVIVIGATNRPDAVDPALRRPGRFDREFYFPLPDVKARFKILQIQTRKWSSPLSTNFIDKLAFLTKGYGGADLRSLCTEAALISIQRSFPQIYRSNDKLLVDPSKIKVKVSDFMLALKKIVPSSARSTGSSPQPLPELIKPLLADQLNNLKNKLDYMLNIKDTTFQRNTSLLQNFIDYEEYSGEEEEHDKYGGNEDTSSFRSYEFFESMAESQICKPRLLINGPKGNGQQYVGAAILNYLEEFNVQNLDLASLVSESSRTIEAAVVQSFMEAKKRQPSVVFIPNLDIWINTIPENVILVLSGLFRSLQSNEKILLLCLAENLDISEVKNGILSDFAFDKNIFQLHKPSKENITRYFSNLIELLKTKPSDIPMKKRRVKPLPELQKVTSNAAPTNFDENGEPLSEKVVLRRKLKSFQHQDMRLKNVLKIKLSGLMDLFKNRYKRFRKPPIDDAFLVHLFEPETSNDPNWQPAYIKDENMILEVSTGRKFFNMDLDIVEERLWNGYYSEPKQFLKDIELIYRDANTIGDRERVIKASEMFANAQMGIEEISTPDFIQECKATRQRDLERQELFLEDEEKRAAMELEAKEQSQENILQEPDLKDNKANEFGVAAGNQLQAQLQTTINTASIVNNSEVPQPIDTNLYKKEIPAAIPSAVDKEKAVIPEDSGANEEYTTELIQATCTSEITTDDDERARKEPKENEDSLQTQVTEENFSKIDANTNNINHVKEIQSVNKPNSLHETVEKRERSPIPKEVVEPEQGKKSDKELILTPEQIKKVSACLIEHCQNFTVSQLEDVHSSVAKIIWKSKSAWDKTGTVDEIIKFLSE
What is the function of this protein?
Functions as an ATP-dependent nucleosome disassembly factor that helps evict canonical histone H3 from the 5'-end of genes upon their induction (PubMed:25406467).  Also contributes to kinetochore assembly by cooperating with SCM3 to load the histone H3 variant CSE4/CENP-A at centromeres (PubMed:32079723).  Provides a chromatin boundary function at the 5'-end of genes that restricts access by RTT106 and thus prevents ectopic spreading of repressive chromatin into coding regions (PubMed:19683497, PubMed:25406467, PubMed:22156209).  Also prevents heterochromatin spreading downstream of the silent mating-type locus HMR, this function is independent of the tRNA boundary element (PubMed:16079223).  Contributes to appropriate cell cycle regulation of histone gene expression by recruiting RNA polymerase II to histone genes, and subsequent CDK1- and casein kinase II-dependent eviction from chromatin is required to promote transcriptional elongation (PubMed:22156209).
What are the official names of this protein?
ATPase histone chaperone YTA7, ATPase family AAA domain-containing protein YTA7, AAA-ATPase, Tat-binding homolog 7.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Chromosome, centromere. Nucleus. Chromosome. Note=Binds near the 5'-end within protein-coding genes (PubMed:25406467, PubMed:19683497). Localizes to the negative regulatory element NEG and promoter of the HTA1 gene during G2 and M-phase, and its open reading frame during G1/S (PubMed:22156209, PubMed:19683497).
Protein: DAPB_AZOVD
Sequence: MRRIAVMGAAGRMGKALIEAARQAPGAGLTAAIGRPDSTLVGVDAGELAGQGRIGVSLSGELATVLDRFDVLIDFTHPTVTLKNLDICRRAGKAMVIGTTGFSADERRMLDEAAREIPIVFAANFSVGVNLCLKLLDTAARVLGDEVDIEIVEAHHRHKVDAPSGTALRMGEVVASALGRDLQKVAVYGREGQTGARTRETIGFATVRAGDIVGDHTVLFAAEGERVEITHKASSRMTFAKGAVRAALWLEGRDPALYDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCF1_AJECH
Sequence: MSNTPLPSSFDAHPEFFQETKWQKFTRRIKEEPLIPIGYAATSYALWRAYKSMKAGDSVELNRMFRARIYGHAFTLFAIVAGGIYYGQERRQRKEFEKALQQKQDQEKRDAWLKELEIRDKEDKDWRQRHAAIEMAAKEAEKKRG
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: POXA_PENOX
Sequence: MPASDRTSETGDVEKVTAAETPKEVPASNAAESTALTGLPLYTVLVGLGLALFLGAMDMAMLGTAVPSITSTFHTTADIGWYGAAYPLTMSSIQLLAGKIYAQFPQKLVFLVFFGLFMLGSLLCGVAVNSPMFIVGRATAGAGAAGVLSGTLAIVSAVVPLDKQSLILGLMMSLVGTAVVLGPVISGLLTDHSTWRWCFYLNLPCGGVTLLALILFFRPPKRPTRTTPLSIPELIKKLDLAGCLGFIPAVVMLLLALQWGGDGSKEHAWNSATIIGLFCGAGVSLILFLIWEHYQGDDAMLPLKFFRDLTIIASCLYGFALLGGYVVVGYFLPEWFQIIKGANPQSSAVMLLPNVITNFISKAVIGVIVNKTGYFNPWLFFGAAVLAIGSGLETNFHPSTPRPNWIGYQILQGAALGIIQAPTLGVQVALAKQKHLIPVALSLVIFFQYFGSSIMLSISLTIFQNLLRPGLVSKAGMTEAQVQQYVAAGNSEVRELTAQIDPSRLGVVLEVYNDAIAGVMWLSTAAALFGFLVSFGFPWKSLKAQTEENKKEAAEEEEEVKVAAVEA
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of oxaleimides, cytotoxic compounds containing an unusual disubstituted succinimide moiety.
What are the official names of this protein?
MFS-type transporter poxA, Oxaleimides biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ULAE_ECOLU
Sequence: MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETDDRLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYPLMNSISKALGYTHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMAKAGMVEAA
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 3-epimerase UlaE, L-ascorbate utilization protein E, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: GUAA_BRUO2
Sequence: MSTTAYPDTILIIDFGSQVTQLIARRVREANVYCEIVPFQSADEAFKRLQPKGVILSGSPHSTTDIGSPRAPQAIFDAGIPVLGICYGEQTMCAQLGGNVESGHDREFGRAFLDVQEDSPLFAGIWAKGTRHQVWMSHGDRVTSLPDGFTIIGTSPNAPYAVIADEKRKYYGVQFHPEVVHTPDGAKLLQNFVHRIVGVKPGWTMGAYREQAVEAIRKQVGSGKVICALSGGVDSSVAALLAHEAVGDQLTCILVDHGLMRKDEAQQVVEMFREHYNLPLILVDASDRFIGALESESDPEKKRKTIGRLFIEVFEEEARKLGGADFLVQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRLLGKELGLPDSFIGRHPFPGPGLAIRCPGGVTREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMNFLGNAATRIINEVRGINRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: LEU3_BUCRP
Sequence: MKKKFRIAVLPGDGIGPEIMREAYKILNILEKNFSLPLEIREFSVGGIAIDREGIALPEETLRGCENSDAILFGSVGGKKWDYLPIESRPERASLLPLRKHFNLFSNLRPAKLYSDLKNLSPLRSNIVRNGFDILCVRELTGGIYFGKPKGRSKNENGEYSFDTEIYYDFEIKRIAHLAFELASSRRCKVCSIDKSNVLASSILWREIVEEVSKNYPNIILSHLYIDNACMQIIKNPSQFDVLLCSNIFGDIISDECAMITGSIGMLPSASLNSKKFGLYEPAGGSAPDIEGKNIANPIAQILSLSMLIRHSMNLNEIADKIDSSVYRALKAGYRTLDISDGKNYIKTNEMGDIIAKFLINGK
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity).
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPG2_RICCN
Sequence: MSLNFSRFQYISNIFFILIISFPGGLIYLLIGSTLSFWLRESGFDKITIGLFSLVNFIHIFKFLWGPLLEKVSFAPLSKRGYKYCLIIALVSCIFCVYVLTNFNPNTHFIPFALCLVAVAFFSSIYDMLLQSSQMLLITNKNWGISEAACTTGFRIGILIAGSGALYLSTIISWQDVYRAMAILCIPSLLLIIIYPLKFKDKIIINDFDRFWHAFYDFVKKPKWLIIVSFMLLYRLQDNFLSVMPNMFYLDIGYTKKDLALGYKAFGMCATILGGFIGGFLCRKYEYSYLLKRVLIYHALSSLSFLFLYFYNRDITSLYIAVFFQEFTKGLTMSPFFSYQLRCCSAKYCITQIALITSIAYISTILFGSISGYAATYLGWTYFFIVAGFCFIPAYILIRYLPPYVISS
What are the official names of this protein?
Putative transporter AmpG 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOC_MYCSK
Sequence: MLDVNFFDELRIGLATADDIRQWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITDVNDEMRHNELSTLEAEMVVEKKAVEDQRDADLEARAQKLEADLAELEAEGAKSDVRRKVRDGGEREMRQLRDRAQRELDRLDEIWTTFTKLAPKQLIVDEVLYRELVDRYGEYFTGAMGAESIKKLIENFDIEAEAENLRETIRSGKGQKKLRALKRLKVVAAFQTNRNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGKPLAMPRLDMVTGLYFLTTMIEGDKGEYRPAATDQPEEGVYSSPAEAIMAMDRGALSVRAKIKVRLTQLRPPAALEAELFENGWKPGLAWTAETTLGRVMFNELLPISYPFINEQMHKKVQARIINDLAERFPMIVVAQTVDKLKDAGFHWATRSGVTVSMADVLVPPQKQEILDRYEAEADGIERKYQRGALNHKERNDSLVKIWQDATEEVGKALEEHYPADNPIITIVKSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPIKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCETERGINVTLAERQPDGSLIRDPHVETSAFARTLATDAVDADGNVVIERGHDLGDPAIDKLLAAGIDHVKVRSVLTCASATGVCAMCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGEDITGGLPRVQELFEARVPRNKAPIADVSGRVQLEEGERFYKITIVPDDGGEEVVYDKLSKRQRLRVIKHEDGSEGVLSDGDHVEVGDQLMEGSADPHEVLRVQGPREVQIHLVHEVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGATEFLPGSLTERAEFESENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLQGLKENVIIGKLIPAGTGINRYRNIQVQPTEEARAAAYTIPSYEDQYYSPDFGQATGAAVPLDDYGYSDYR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.