PharMolix/UniProtQA huggingface dataset:
Protein: OBG_STRPI
Sequence: MFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGGNVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAETGKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKILADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGLIEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLMERPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATAELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNFDRDESVMKFARQLRGMGGDEALRARGAKDGDLVRIGKFEFEFVD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_MYCBT
Sequence: MLSPEALTTAVDAAQQAIALADTLDVLARVKTEHLGDRSPLALARQALAVLPKEQRAEAGKRVNAARNAAQRSYDERLATLRAERDAAVLVAEGIDVTLPSTRVPAGARHPIIMLAEHVADTFIAMGWELAEGPEVETEQFNFDALNFPADHPARGEQDTFYIAPEDSRQLLRTHTSPVQIRTLLARELPVYIISIGRTFRTDELDATHTPIFHQVEGLAVDRGLSMAHLRGTLDAFARAEFGPSARTRIRPHFFPFTEPSAEVDVWFANKIGGADWVEWGGCGMVHPNVLRATGIDPDLYSGFAFGMGLERTLQFRNGIPDMRDMVEGDVRFSLPFGVGA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENY2_CULQU
Sequence: MTFTKSVDQTTILQGDRSKLKDLLRVRLNACGWNDQVRLLCRETIKDQDTVNCDALVQQVTPKARALIPDTVKKELLQKIKAILIQQEGIDI
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histones.  The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (By similarity).
What are the official names of this protein?
Enhancer of yellow 2 transcription factor.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: ARSB_STAAS
Sequence: MTTLATLIFLVTLLFVLWQPKGLDIGITALTGAFIAVITGVVSFSDVFEVTGIVWNATLTFVSVILISLILDKVGLFEWSAIHMLHASKGNGLKMFAYIILLGAIVAAFFANDGAALILTPIVLAMVKNIGFSKRAIFPFIIASGFIADTTSLPLIVSNLVNIISADYFHIGFIRYFSRMIIPNLFSLLASIIVLWLYFRKAIPKTFDDNNIKHPKDAINDLKLFKISWIVLVILLFGYLISEFTKIPVSIFTGIIAFIFLMLARKSNALNIKQVIKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLFSTILGMGFISAFLSSIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVLTQKDVKISWGTYFKTGIIITIPVLFITLIGLYLTLIIF
What is the function of this protein?
Involved in arsenical resistance.  Thought to form the channel of an arsenite pump.
What are the official names of this protein?
Arsenical pump membrane protein, Arsenic efflux pump protein.
What is the protein family that this protein belongs to?
Belongs to the ArsB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS13_MYCSJ
Sequence: MARLVGVDLPRDKRMEIALTYIYGVGRTRSQEILEATGIDRDLRTKDLTDDQVTQLRDYIEANLKVEGDLRREVQADIRRKIEIGCYQGLRHRRGLPVRGQRTKTNARTRKGPKRTIAGKKKAR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: YM17_PARTE
Sequence: MPLIFYSSCCFFLVSTSAFCSWVCSRPSQSSLCSLCLSCLFFILLFWSPSTSYLILVFFLLYTCVVLQTQLAYSLSAFMNYIGVLAFFTRLIVQFLRLVLMFVVYCMMHDTVMLQNYSQKNFLVGDSFWEELMSVQPNGTSIFFFLFATFPLRLFYWCYECMHTFFVVTVQFSAFFTIVFWLFLLFYTFFVYEKYEHHFDNITKMHKKLIEELKSLKKDSF
What are the official names of this protein?
Uncharacterized mitochondrial protein ORF17.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RSMH_LIMRD
Sequence: MAEFKHVTVLLKEAVAGLNVQPTGTYVDATLGGGGHTQAILQQLVDGHLYSFDQDQTAIDYNKEHLKTAIEQQKLTLVEDNFRNLKAELNSYNVKHVNGILYDLGVSSPQFDDAKRGFSYQHDAPLDMRMNQEQKLSAMEVVNEWPYERLVKILYRYGEEKFAKSIARKIEQRRKVAPIKTTFELVDVIKEGIPAAARRHGGHPAKKSFQAIRIAVNDELGALEESLEQALDLLDVGGRISVITFQSLEDRLVKTMFREKTSLSGDVPQGLPVIPAGMEPNFKLINKKPIVASDEELAANHRAHSAKLRIIEKIREGK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_BACC7
Sequence: MNIAKLIDHTILKANATKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTVIGFPLGASTTETKAFETKDAIAKGATEVDMVINVGALKDGDDELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGVKASGGVRTREDADKMVAAGASRIGASASVAIVLNDAKDATDNY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_ECODH
Sequence: MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGMEIAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYDPSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAAMLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: AAKB1_MOUSE
Sequence: MGNTSSERAALERQAGHKTPRRDSSGGAKDGDRPKILMDSPEDADIFHSEEIKAPEKEEFLAWQHDLEANDKAPAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSQNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELSSSPPGPYHQEPYMSKPEERFKAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI
What is the function of this protein?
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.  In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.  AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.  Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.  Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3) (By similarity).
What are the official names of this protein?
5'-AMP-activated protein kinase subunit beta-1, AMPK subunit beta-1, AMPKb.
What is the protein family that this protein belongs to?
Belongs to the 5'-AMP-activated protein kinase beta subunit family.
Protein: PSBP_BRAJU
Sequence: EDDTSTVSRRLALTLLVGAAAVGSKVSPADAAYGEAANVFGKPKTNTDFTAINGDGFQVQVPAKWNPSREVEYPGQVLRYEDNFDATSNLNVMVTPTDKKSITDYGSPEEFLSQVNYLLGKQAYFGETACEGGFDNNAVATANILETNIQDVGGKPYYYLSVLTRTADEDEGGKHQLITATVNGGKLYICKAQAGDKRWFKGANKFVEKAATSFSVA
What is the function of this protein?
May be involved in the regulation of photosystem II.
What are the official names of this protein?
Oxygen-evolving enhancer protein 2, chloroplastic, OEE2, 23 kDa subunit of oxygen evolving system of photosystem II, 23 kDa thylakoid membrane protein, OEC 23 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the psbP family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: BPHA2_PSES1
Sequence: MTRVAMAQKTAELIQEFAWPAQPVSPQLQHEVEQFYYREAQLLDHHNYNAWFDLLEQDIHYWMPIRTTRIKRENDKEYIPAGANAHFDENHETMRGRIRQRTSELNWAEDPLSRTRHIVSNVIVRETDTPATLEVASAFLVYRNRLERQVDIFAGERRDVLRRANNGLGFKIARRTILIDQSTILANNLSVFF
What is the function of this protein?
The beta subunit may be responsible for the substrate specificity of the enzyme.
What are the official names of this protein?
Biphenyl dioxygenase subunit beta, Biphenyl 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.
Protein: RL5_POLAQ
Sequence: MSTRFQEHYQEKVVADLITKFGYKSVMEVPRITKVTLNMGLGDAVNDKKIIENAVGDLTKVAGQKPVVTKAKKAIAGFKIRQGYPIGAMVTLRGQRMYEFLDRFVTVALPRVRDFRGISGKAFDGRGNYNIGVKEQIIFPEIEYDKIDALRGLNISITTTAKTDEEAKALLAAFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TRM1_PYRAR
Sequence: MSRIVLRREGTVEFYAPDPRAYGSIYSAPVFYNPAMEKNRTLSVLFLKAYGATGLTVCEPLSGTGVRGIRYAVETGAVGRLILNDISREAVELIKKNLEVNGVDAEVYNEDANVLLHRLRDKCDVVDIDPFGSPAPFLQAGFRALREEGVICVTATDTAVLVGRYPKKCLRRYGAVMFKTPFYIEAGLRNLTGYVARVAASEDYGFEPLFAYWEGHYFRLCARAVRGARDADSNFNFIGYVEYKKPSRKVVRRPGERSLGPLWVGPMGDPILVNKMAEYGPYGDFLQLLSEEYSVAAPWFFKVPEFALGGVSRGIEEALNALKKGGIYAVRTHMAPDGFKTEVSAGEVERVLRIVI
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: RS10_TRIEI
Sequence: MATIQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTGATAIGPIPLPTKRRIYCLLRSPHVDKDSREHFETRTHRRIVDIYQPSSKTIDALMKLDLPAGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: FAL1_GIBZE
Sequence: MAEGSGIDRKADERMEFSTSKEVTVHPTFESMSLKENLLRGIYAYGYESPSAVQSRAIVQVCKGRDTIAQAQSGTGKTATFSISMLQVIDTAVRETQALVLSPTRELATQIQSVVMALGDYMNVQCHACIGGTNVGEDIRKLDYGQHIVSGTPGRVADMIRRRHLRTRHIKMLVLDEADELLNKGFREQIYDVYRYLPPATQVVVVSATLPYDVLDMTTKFMTDPVRILVKRDELTLEGLKQYFIAVEKEDWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGDMPQKERDSIMQDFRQGNSRVLISTDVWARGIDVQQVSLVINYDLPSNRENYIHRIGRSGRFGRKGVAINFVTTEDVRILRDIELYYSTQIDEMPMNVADLIA
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase FAL1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ENY2_DROAN
Sequence: MTVSNTVDQYTVLSGDRSKIKDLLCNRLTECGWRDEVRLLCRTILLEKGTGNSFTVEQLITEVTPKARTLVPDAVKKELLMKIRTILTENESEIEDAEEP
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes.  The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B.  The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.  Required for nuclear receptor-mediated transactivation.  Involved in transcription elongation by recruiting the THO complex onto nascent mRNA.  The AMEX complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  AMEX participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (By similarity).
What are the official names of this protein?
Enhancer of yellow 2 transcription factor.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm.
Protein: EMP24_YEAST
Sequence: MASFATKFVIACFLFFSASAHNVLLPAYGRRCFFEDLSKGDELSISFQFGDRNPQSSSQLTGDFIIYGPERHEVLKTVRDTSHGEITLSAPYKGHFQYCFLNENTGIETKDVTFNIHGVVYVDLDDPNTNTLDSAVRKLSKLTREVKDEQSYIVIRERTHRNTAESTNDRVKWWSIFQLGVVIANSLFQIYYLRRFFEVTSLV
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi.
What are the official names of this protein?
Endosomal protein P24B, 24 kDa endomembrane protein, Basic 24 kDa late endocytic intermediate component.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Recycles between endoplasmic reticulum and Golgi (PubMed:11560939).
Protein: MSPI1_MELSA
Sequence: EQQCTPGQTKKEDCNNCTSGD
What is the function of this protein?
Probable serine protease inhibitor.
What are the official names of this protein?
Serine protease inhibitor 1, Protease inhibitor MSPI-1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I19 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TIG_XYLF2
Sequence: MPVLIESIGNLERRLTFSVPEDRLESHVDERLREIARAARINGFRAGKVPAKVIEQRFGEKVRAEVLDSLLRETLDSAIRAHSLRLAGAARIDHANEGGLNFVATFEVVPDFGEIDVSKLGVVRRTAKVTDVDIDQMIENLRLQRRTWRVAEHGAQVGYLVALETWSQAGDERLPIEGVEAGSTILGSGVMFEQIERGLEGLSKGDENVLDVTFPDDWRVMQLAGKAVQVHVKVIEVSEPVLLEVNEEFIKSFGVKSGKLEDFRADIRANLERELKGALVSHLRREIGEQLIAAYAHVEMPPRLVEKEARLMLAKQIEQIRLSGRDPTVIPDDAHIGFMDAACKRVLVGLLVGEIAGRNRLRLDPMRVTETLHLIASTYEEPEEVFQMYRNDPKLMEGVQSLVMEEQVIEWIADRAQKTEQVLSFQEAIQQ
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: IGBP1_HUMAN
Sequence: MAAEDELQLPRLPELFETGRQLLDEVEVATEPAGSRIVQEKVFKGLDLLEKAAEMLSQLDLFSRNEDLEEIASTDLKYLLVPAFQGALTMKQVNPSKRLDHLQRAREHFINYLTQCHCYHVAEFELPKTMNNSAENHTANSSMAYPSLVAMASQRQAKIQRYKQKKELEHRLSAMKSAVESGQADDERVREYYLLHLQRWIDISLEEIESIDQEIKILRERDSSREASTSNSSRQERPPVKPFILTRNMAQAKVFGAGYPSLPTMTVSDWYEQHRKYGALPDQGIAKAAPEEFRKAAQQQEEQEEKEEEDDEQTLHRAREWDDWKDTHPRGYGNRQNMG
What is the function of this protein?
Associated to surface IgM-receptor; may be involved in signal transduction.  Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.
What are the official names of this protein?
Immunoglobulin-binding protein 1, B-cell signal transduction molecule alpha 4, Protein alpha-4, CD79a-binding protein 1, Protein phosphatase 2/4/6 regulatory subunit, Renal carcinoma antigen NY-REN-16.
What is the protein family that this protein belongs to?
Belongs to the IGBP1/TAP42 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPC12_HUMAN
Sequence: MEDAGGGEETPAPEAPHPPQLAPPEEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHMMESVLISDSPNSEGDAGDLGRVRDEAEPGGEGDPGPEPAGTPSPSGEADGDCAPEDAAPSSGGAPRQDAAREVPGSEAARPEQEPPVAEPVPVCTIFSQRAPPASGDGFEPQMVKSPSFGGASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSAFISVSNPGAGSPAPASPPPLAVPGTEGRPEPVAMRGPQAAAPPASPEPFAHIQAVFAGSDDPFATALSMSEMDRRNDAWLPGEATRGVLRAVATQQRGAVFVDKENLTMPGLRFDNIQGDAVKDLMLRFLGEKAAAKRQVLNADSVEQSFVGLKQLISCRNWRAAVDLCGRLLTAHGQGYGKSGLLTSHTTDSLQLWFVRLALLVKLGLFQNAEMEFEPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSMRILHAELQQYLGNPQESLDRLHKVKTVCSKILANLEQGLAEDGGMSSVTQEGRQASIRLWRSRLGRVMYSMANCLLLMKDYVLAVEAYHSVIKYYPEQEPQLLSGIGRISLQIGDIKTAEKYFQDVEKVTQKLDGLQGKIMVLMNSAFLHLGQNNFAEAHRFFTEILRMDPRNAVANNNAAVCLLYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLTTMYELESSRSMQKKQALLEAVAGKEGDSFNTQCLKLA
What is the function of this protein?
Component of the TRAPP complex, which is involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage (PubMed:21525244, PubMed:28777934).  Also plays a role in chromosome congression, kinetochore assembly and stability and controls the recruitment of CENPE to the kinetochores (PubMed:25918224).
What are the official names of this protein?
Trafficking protein particle complex subunit 12, Tetratricopeptide repeat protein 15, TPR repeat protein 15, TTC-15, Trafficking of membranes and mitosis.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment. Nucleus. Note=Mainly localizes to structures resembling the Golgi and a small amount is found in the nucleus.
Protein: TX90B_PHORI
Sequence: GCKARGDTCQKDCDCCGCFYKCHCPLDWFGGKWHPLGCSCVYGDKYICEKKKKECPNV
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
U7-ctenitoxin-Pr1a, U7-CNTX-Pr1a, PRTx19, Probable neurotoxin PRTx20C1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 09 (Tx3-6) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMA_ESCF3
Sequence: MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQQAEVLRDALRAQNLNVHLIGRATKTKIELDQDYIDERLPVAGREMIYRQVENSFTQPNAAMNIQMLEWALDVTKDSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: LEUC_SHEPC
Sequence: MTTVPKNAVAKTLYQKVWDAHVVATPEGEAPIIYVDRHLVHEVTSPQAFSGLKVAGRKLRAPEKTFATMDHNTSTRSASLDALSPMARTQVETLAQNCKDFGVRLYDIHHPNQGIVHVMGPELGITFPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLRQLKAKTMKIEVRGHVSDGVTAKDIVLAIIGKIGMDGGTGYVVEFCGEAIEALSMEGRMTVCNMAIEMGAKAGMVAPDQTTFDYLAGREFAPKGEDWAEAVAYWQAIKTDDGAVFDAVVELDAADIAPQLTWGTNPGQVVAIDGKVPNPLDEANPSTRASMEKALEYIGLSAGTPMTDISINKVFIGSCTNSRIEDLRSAAVHAKGRKVASGVTAIVVPGSGQVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNDDRLEAGDRCASTSNRNFEGRQGRGSRTHLVSPAMAAAAAVAGHFVDIRKPY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: YABA_STAA9
Sequence: MDRNEIFEKIMRLEMNVNQLSKETSELKAHAVELVEENVALQLENDNLKKVLGNDEPTTIDTANSKPAKAVKKPLPSKDNLAILYGEGFHICKGELFGKHRHGEDCLFCLEVLSD
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: DHQS_METB6
Sequence: MKQFWVDARPWNKDVVTTAIESGADAVVAEKAADVKRLGRITTVAPDGDLVPGKDVIECTITDKASENEAAANGKNRIVIVTTSDWTVIPLENLVAQSDKIIAEVKNVHEAELAIHVLEKGVYGILLKTSDPAVVKAVAALVKSTSGSVQLVPFTVTKIHPVGMGDRVCVDTCSMLADGDGMLMGNTSSAMLLVHAETLENPYVAPRPFRVNAGAVHAYILLPDGKTAYLADLSIGGQVLVSDHKGAGRSAIVGRTKIERRPLLLVEATAEGGAKASLILQNAETIRLVAPDGSAISVVNLAPGNKILGCALEGGRHFGMAVKETIREK
What is the function of this protein?
Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.
What are the official names of this protein?
3-dehydroquinate synthase, DHQ synthase, 3-dehydroquinate synthase II.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type DHQ synthase family.
Protein: PAIP2_CHICK
Sequence: MKDPSRSSTSPSIISEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDSSSLEDLVVKSNLNPNAKEFVPGVKYLNI
What is the function of this protein?
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs.  Its inhibitory activity on translation is mediated via its action on PABPC1.  Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1.  Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein-interacting protein 2, PABP-interacting protein 2, PAIP-2, Poly(A)-binding protein-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the PAIP2 family.
What are the subcellular locations of this protein?
Cytoplasm.