PharMolix/UniProtQA huggingface dataset:
Protein: MALT_SALA4
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALVTSPAGYGKTTLVSQWAAGKNELGWYSLDEGDNQQERFASYLIAAIQQATGGHCSTSEAMAQKRQYASLTSLFAQLFIELAQWHRPLYLVIDDYHLITNPVIHDAMRFFLRHQPENFTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFNHQEAKQFFDRRLSSPIEAAESSRMCDDVAGWATALQLIALSARQNHTSAHHSARRLAGINASHLSDYLVDEVLDNVDVSTRHFLLKSAILRSMNDALIVRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFSYHPLFGSFLRQRCQWELAAELPEIHRAAAESWMEQGFPSEAIHHALAAGDAQMLRDILLNHAWGLFNHSELALLEESLKALPWESLLENPRLVLLQAWLMQSQHRYSEVNTLLARAEQEIKGVMDGTLHAEFNALRAQVAINDGNPEEAERLAKLALDELPLAWFYSRIVATSVHGEVLHCKGDLSQSLSLMQQTEQMARHHDVWHYALWSLIQQSEIQFAQGFLQAAWETQERAFQLIKEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIAVLSTFQPQQQLQCLTLLVQCSLARGDLDNARSQLNRLENLLGNGRYHCDWISNADKVRVIYWQLTGDKKSAANWLRHTPKPAFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQSGRKNDAQRVLLDALQLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPEMEQHRAQRILREINQHHRHKFAHFDEGFVERLLNHPDVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELAVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: LEU3_BACFR
Sequence: MDFKIAVLAGDGIGPEISVQGVEVMSAVCEKFGHKVNYEYAICGADAIDKVGDPFPEETYRVCKNADAVLFSAVGDPKFDNDPTAKVRPEQGLLAMRKKLGLFANIRPVQTFKCLVHKSPLRAELVEGADFLCIRELTGGMYFGEKYQDNDKAYDTNMYTRPEIERILKVGFEYAMKRRKHLTVVDKANVLASSRLWRQIAQEMAPQYPEVTTDYMFVDNAAMKMIQEPKFFDVMVTENTFGDILTDEGSVISGSMGLLPSASTGESTPVFEPIHGSWPQAKGLNIANPLAQILSVAMLFEYFDCKAEGALIRKAVDASLDANVRTPEIQVEGGEKFGTKEVGAWIVDYIRKA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity).
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCH_MYCTU
Sequence: MLHRDDHINPPRPRGLDVPCARLRATNPLRALARCVQAGKPGTSSGHRSVPHTADLRIEAWAPTRDGCIRQAVLGTVESFLDLESAHAVHTRLRRLTADRDDDLLVAVLEEVIYLLDTVGETPVDLRLRDVDGGVDVTFATTDASTLVQVGAVPKAVSLNELRFSQGRHGWRCAVTLDV
What is the function of this protein?
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB.  Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation.  Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
What are the official names of this protein?
Probable protein archease.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: F149B_RAT
Sequence: MELDQNATEKVKAMFTAIDELLYEQKPSVHTQSLQKECQQWASSFPHLRILGRQIITSSEGYGLYPRSPSAVSASHEAILPQERESTIFGIRGKKLHFSSSYKASPSTKASGSSADGEEADCIIFSEGIIEEYLAFDHTDMEEGFHGNKSEAATEKQKLGYPPIAPFYCMKEDVLAYVFDNVWSKAVGCMEQLTRSHWEGFASDDESNVEITRLDSGSPYMLNEQQPLVLPRVPQSKVMSVTSNPMNFCQASGHQPNVNGLLIHGMPLQPRNLSLMDKLLDLDDKLLMRPGSSSVLSNRNWPNRAMELSTSSLSYTTQSARRRNPPPRTLHPISTSHSRTGTPWPAEEILRGPRLPMTADSLSSPSPMTMGRNNLLPPIGTADVEHLSILGSQRPTKPHGDSSRARSAAVDEPNQQPQERLLLPVFSRPNTTQSFLPETQYRSSCASECPHHARPGRGSAGPQSHGSTKPQSRGGPISRTRQ
What is the function of this protein?
Involved in the localization of proteins to the cilium and cilium assembly.  Indirectly regulates the signaling functions of the cilium, being required for normal SHH/smoothened signaling and proper development.
What are the official names of this protein?
Primary cilium assembly protein FAM149B1.
What is the protein family that this protein belongs to?
Belongs to the FAM149 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: ORNAT_THEKO
Sequence: MVVRPNVKELPGPKAKEVIERNFKYLAMTTQDPENLPIVIERGEGIRVYDVDGNVFYDFASGVGVINVGHSHPRVVEAIKKQAEKFTHYSLTDFFYENAIILAEKLIELAPGDIERKVVYGNSGAEANEAAMKLVKYGTGRKQFLAFYHAFHGRTQAVLSLTASKWVQQDGFFPTMPGVTHIPYPNPYRNTWGIDGYEEPDELTNRVLDFIEEYVFRHVPPHEIGAIFFEPIQGEGGYVVPPKGFFKALKKFADEYGILLADDEVQMGIGRTGKFWAIEHFGVEPDLIQFGKAIGGGLPLAGVIHRADITFDKPGRHATTFGGNPVAIAAGIEVVEIVKELLPHVQEVGDYLHKYLEEFKEKYEVIGDARGLGLAQAVEIVKSKETKEKYPELRDRIVKESAKRGLVLLGCGDNSIRFIPPLIVTKEEIDVAMEIFEEALKAALK
What is the function of this protein?
L-ornithine aminotransferase involved in L-proline biosynthesis.  Also shows high activity toward L-lysine.  2-oxoglutarate is the best amino acceptor, but 2-oxoadipate also leads to moderate activity.
What are the official names of this protein?
Ornithine aminotransferase, Orn-AT, Lysine aminotransferase, Lys-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: PHYD1_RAT
Sequence: MACLSPSQLKKFQEDGFLLLEGFFTADECVVMQQRIGEIVAEMDVPLHCRTEFSTQEDEQLQTQGNTDYFLSSGDKIRFFFEKGVFDEKGNFLVPPEKSINKIGHALHAHDPVFRSITHSPKVQALVRSLGLQIPVVVQSMYIFKQPHFGGEVSPHQDATFLYTEPLGRVLGLWIATEDAMLENGCLWFIPGSHTSGVSRRMIRAPSDSGPGTSFLGSEPAWDNNLFVPLPVRRGGLVLIHGEVVHKSEQNLSDHSRQAYTFHLMEAAGTVWSPGNWLQPTTELPFPPLYI
What is the function of this protein?
2-oxoglutarate(2OG)-dependent dioxygenase that catalyzes the conversion of 2-oxoglutarate to succinate and CO(2) in an iron-dependent manner.  However, does not couple 2OG turnover to the hydroxylation of acyl-coenzyme A derivatives, implying that it is not directly involved in phytanoyl coenzyme-A metabolism.  Does not show detectable activity towards fatty acid CoA thioesters.
What are the official names of this protein?
Phytanoyl-CoA dioxygenase domain-containing protein 1, Protein PHYHD1.
What is the protein family that this protein belongs to?
Belongs to the PhyH family. PHYHD1 subfamily.
Protein: SYL_STRM5
Sequence: MTSVEPNVYDPQQVESAAQQYWDATRAFEVDEASDKPKYYCLSMLPYPSGALHMGHVRNYTIGDVISRYKRMTGHNVLQPMGWDAFGLPAENAAIKNKTAPAAWTYKNIDHMRTQLKSLGYAIDWSREFATCRPDYYVHEQRMFTRLMRKGLAYRRNAVVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPQWFLRITDYAQELLDGLDELDGWPESVKTMQRNWIGRSEGLEIQFDVRDVDGGVLDPLRVFTTRPDTVMGVTFVSIAAEHPLALHAAKNNPELAALLADLKQGGVSEAELETQEKRGMDTGLRAIHPVTGEQVPVWVANFVLMGYGTGAVMAVPGHDQRDNEVANKYGLPIVQVIALKDPRSEEERSWDATRWQDWYSDKSRAFELVNSAEFDGLDFQGAFEALAERFERKAQGQRRVNYRLRDWGVSRQRYWGCPIPVIYCAKCGAVPVPEEQLPVVLPEDVAFAGTGSPIKTDPEWRKTTCPECGGAAERETDTFDTFMESSWYYARYTSPGARDAVDKRGNYWLPVDQYIGGIEHAILHLMYFRFYHKLLRDARMVDSNEPARNLLCQGMVIAETYYRPNPDGSRDWINPADVDVQRDERGRITGATLIADGQPVVVGGTEKMSKSKNNGVDPQAMVGKYGADTVRLFSMFAAPPEQSLEWNEAGVDGMARFLRRLWAQVQKHAADGAAPALDVAVLDASQKALRRKTHETIGKVGDDYGRRHSFNTAIAAVMELMNALAKFDDGSDQGRAVRQEALQAIVLLLNPITPHASHTLWQVLGHGETLLEDQPFPQADAAALVRDALTLAVQVNGKLRGTIEVAADAPREQVEALALAEPNAAKFMEGLTVRKIIIVPGKIVNIVVA
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MK16A_XENLA
Sequence: MQHDDVIWDVVGNKQFCSFKIKTKTQNFCRNEYNITGLCNRSACPLANSQYATIKEEKGICYLYMKTIERAAFPARMWERVRLSKNYEQALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALVAAQLDNAIEKELLERLKQGAYGDIYNFPIQAFDKALEQQEDASASESSADEEEEDDEEIGKREFVEDDNVDESDLSDFEDMDKLGASGDEDKHSSESEEESSEEEEEAGKAKSKGKAPLKGHLIRKRPRVEIEYEQETEPQHKAKVT
What are the official names of this protein?
Protein MAK16 homolog A, MAK16-like protein A.
What is the protein family that this protein belongs to?
Belongs to the MAK16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: COAX_CLOP1
Sequence: MILLIDVGNTNIVLGIHDNEKYIASWRISTDSKKTSDEYSIQVMQLFNQAKLNPEEVEGIIISSVVPNIMHSLENMVRKCFCKEPIVVGPGIKTGINIKYDNPKEVGADRIVNAVAAFEKHKKPMIIIDFGTATTFCAITEKGDYLGGNICPGIQISADALFERAAKLPRIELEKPKSVICKNTVTSMQAGIIYGYIGKVEYIVKRMKKEMMDLGEKEPFVLATGGLAKLVYSETDVIDEVDRKLTLEGLKILYEKNKE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHBG_YERPA
Sequence: MEKLLIVNADDFGLCKGQNYGIIDAFRNGVVSSTTAMMNSVDINHAAELSAQYPALPVGMHFVLTFGRPLTAMPSLTDANGELGKWLWQRAGAGTLDLNEIAQELECQFERFSAVFGRPPTHIDSHHHVHMLPQIYPLVAAFAREKSLPLRIDRHEVQQHGLTLDNPRSSEWFNAGFYGENLSEPSFLQLLEHADQQGVNSLEIMCHPAFIDQTLMTSGYCYPRLTELAILTSPTLKPAIAQRGYRLGSFLDC
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_SHEB8
Sequence: MAPKVFYISDGTAITAEVFGHAVLSQFPLEFESLTIPFVETLTKAEQVKRQINDCFITTGERPLVFHSIVKAEIRDIIYSSEGLDYDFLNTFVAPLEQHLGVSASPVLHRTHGKANHGYEARIDAINFAMDNDDGQTMKHMDQADLVLLGVSRCGKTPSSLYLSMQFGIKAANYPFTEDDMDNLKLPDALKRNKKKLFGLTIDPVRLHEIRQSRMENSRYSSLKQCRLEVKEVEMLFKRERIPYIDTTNHSVEEIATKILDVTGLERHMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: RM51_ASHGO
Sequence: MVVKALRQISVGQNGVGAFIFPCKKITLQYCNWGGSSQGLRDFLTSKRLAKWAEKYPQIQFEVVAKAGHPVLKAEYINGLNKAICVRNLNVDHVELKLKLLRESSGAQLRHYPKNANVLSLNQSVRGVWSPLHVDPALRHRV
What are the official names of this protein?
54S ribosomal protein L51, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL43 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FL2D_DANRE
Sequence: MTNEEPLPKKVRLSESDMKTLTREELCTRWKQHETYVQMLEAKYADLNSNDVTGLKESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSAAQLRSSMVDPAINLFFLKMKAELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLRETRQQLSQMNQTQGTSSGAGPSRTSPSTASEPSTQSEPANASSSNVGKDCGRVSNGPSNGNSSQRGASGSSLYREASSADEDYPPSPSVSSPTHDGISKLSNHSEDAVSQRGGEGYVTQLSAGYESVDSPTGSETSVTQHSNDTDSNADSHEAAAVPKGSRTAGTRHSTQNGLDSSAAAVATNTSNASAGSVL
What is the function of this protein?
Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing.
What are the official names of this protein?
Pre-mRNA-splicing regulator WTAP, Female-lethal(2)D homolog, WT1-associated protein, Wilms tumor 1-associating protein.
What is the protein family that this protein belongs to?
Belongs to the fl(2)d family.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm.
Protein: STX4_BOVIN
Sequence: MRDRTHELRQGDDSSDDEDKERVALVVHPGTARLGSPDDEFFQKVRTIRQTIVKLENKVRELEKQQVTILATPLPEESMKQDLQNLRDEIKQLGRDIRAQLKAIEPQKEEADENYNSVNTRMRKTQHGVLSQQFVELINKCNLMQSEYREKNVERIRRQLKITNAGMVSDKELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHEIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKVALENQKKARKKKVFIAICLSITVLILVVIIVISTLV
What is the function of this protein?
Plasma membrane t-SNARE that mediates docking of transport vesicles (By similarity).  Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane (By similarity).  In neurons, recruited at neurite tips to membrane domains rich in the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) which promotes neurite tip surface expression of the dopamine transporter SLC6A3/DAT by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane (By similarity).  Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes and in docking of synaptic vesicles at presynaptic active zones (By similarity).
What are the official names of this protein?
Syntaxin-4.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type IV membrane protein. Cell projection, neuron projection. Note=Localizes to neurite tips in neuronal cells.
Protein: UBIB_ECOSE
Sequence: MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWMPNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDGKLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAFKEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGATLVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NSP4_ROTME
Sequence: MEKLADLNYTLGVITLLNDTLHNILEEPGMVYFPYVASALTVLFTMHKASLPAMKLAMRTSQCSYRIIKRVVVTLINTLLRLGGYNDYLTDKDETEKQINRVVKELRQQLTMIEKLTTREIEQVELLKRIYDMMVVRHDREIDMSKETNQKAFNTLHDWGNDRNYDDNTDVIAPL
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: MOS_HUMAN
Sequence: MPSPLALRPYLRSEFSPSVDARPCSSPSELPAKLLLGATLPRAPRLPRRLAWCSIDWEQVCLLQRLGAGGFGSVYKATYRGVPVAIKQVNKCTKNRLASRRSFWAELNVARLRHDNIVRVVAASTRTPAGSNSLGTIIMEFGGNVTLHQVIYGAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQSIVHLDLKPANILISEQDVCKISDFGCSEKLEDLLCFQTPSYPLGGTYTHRAPELLKGEGVTPKADIYSFAITLWQMTTKQAPYSGERQHILYAVVAYDLRPSLSAAVFEDSLPGQRLGDVIQRCWRPSAAQRPSARLLLVDLTSLKAELG
What are the official names of this protein?
Proto-oncogene serine/threonine-protein kinase mos, Oocyte maturation factor mos, Proto-oncogene c-Mos.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: UFC1_CAEBR
Sequence: MDETTKSSLKAIPLCKTKAGPRDGDLWMERLKAKYEAIIAAVQNNKTSDRDWFKLEANERGTKWFGKCWYFHNMVKYEFDVEFDIPITYPVTAPEIALPELDGKTAKMYRGGKICLSEHFKPLWARNTPKFGIAHAFALGLGPWMAVEIPDLIEKGIIQPKA
What is the function of this protein?
E2-like enzyme which forms an intermediate with ufm-1.  The intermediate is formed via a thioester linkage.
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: GUAA_CUPTR
Sequence: MHDKILILDFGSQVTQLIARRVREAHVYCEIHPNDVSDAFVREFAPKAIILSGSHASTYEDHQLRAPQAVWDLGVPVLGICYGMQTMAVQLGGKVEWSDHREFGYAEMRAHGHTELLKDIEDFRTPEGHGMLKVWMSHGDKVTGLPPGFKLMASTPSCPIAGMADETRHYYAVQFHPEVTHTVKGRQMLERFVLQIAGCKPDWVMRDHIEEAVAKIREQVGDEEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRQDEGKLVMEMFVGRLHAKVVHVDASEQFLGHLAGVTDPEQKRKIIGREFVEVFQAEARKLTNAKWLAQGTIYPDVVESGGTKTKKATTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVELGLPPEMVYRHPFPGPGLGVRILGEVKRDYADLLRRADAIFIEELRKTIATEHDAAAGLCEPEQVGKSWYDLTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVQTTDFMTAHWAHLPYALLGRCSNRIINEVRGLNRVVYDVSGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: PAPA1_MYCBP
Sequence: MRIGPVELSAVKDWDPAPGVLVSWHPTPASCAKALAAPVSAVPPSYVQARQIRSFSEQAARGLDHSRLLIASVEVFGHCDLRAMTYVINAHLRRHDTYRSWFELRDTDHIVRHSIADPADIEFVPTTHGEMTSADLRQHIVATPDSLHWDCFSFGVIQRADSFTFYASIDHLHADGQFVGVGLMEFQSMYTALIMGEPPIGLSEAGSYVDFCVRQHEYTSALTVDSPEVRAWIDFAEINNGTFPEFPLPLGDPSVRCGGDLLSMMLMDEQQTQRFESACMAANARFIGGMLACIAIAIHELTGADTYFGITPKDIRTPADLMTQGWFTGQIPVTVPVAGLSFNEIARIAQTSFDTGADLAKVPFERVVELSPSLRRPQPLFSLVNFFDAQVGPLSAVTKLFEGLNVGTYSDGRVTYPLSTMVGRFDETAASVLFPDNPVARESVTAYLRAIRSVCMRIANGGTAERVGNVVALSPGRRNNIERMTWRSCRAGDFIDICNLKVANVTVDREA
What is the function of this protein?
Catalyzes the acylation of trehalose-2-sulfate-2'-palmitate (SL659) by adding the (hydroxy)phthioceranoyl group at the 3'-position to yield the diacylated intermediate 2-palmitoyl-3-(C43)-phthioceranyl-alpha, alpha'-D-trehalose-2'-sulfate (SL1278).
What are the official names of this protein?
2'-acyl-2-O-sulfo-trehalose (hydroxy)phthioceranyltransferase PapA1, Polyketide synthase-associated protein A1, SL659 acyltransferase PapA1.
What is the protein family that this protein belongs to?
Belongs to the PapA acyltransferase family.
Protein: EFP_RHOCS
Sequence: MKVNANTMRKGHILEDGGKLYVITAANIVQPGKGGAFIQLEMKDVRTGTKTSMRFRTQETVERARLDEHEMSFLFAEGDQYTFMDKESFEQVTIPGDVIGDGKVFLQDGMEVVVQSFEGAPLSVELPQTVTLRIVEADPVVKGQTASSSYKPAVLENGVRVLVPPHVDAGTRIVVNVEDGTYLERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_SALSV
Sequence: MPESKYRQQTIRAPRGTVLTAKSWLTEAPLRMLMNNLDPDVAENPHELVVYGGIGRAARNWECYDAIVDALTRLEADETLLIQSGKPVGVFKTHDNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYNGTLAGRWVLTAGLGGMGGAQPLAATLAGACSLTIECQQSRIDFRLRTRYVDEQAATLDDALARITRYTREGKAVSVALCANAADILPELVNRGVRPDLVTDQTSAHDPLHGYLPSGWRWEEYQKNAQSDPHGTMQAAKRSMAAHVRAMLAFSQMGVPTFDYGNNIRQMAKEMGVENAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIVAEDKHLHHWLDMARERIHFQGLPARICWVGLEWRQKLGLAFNEMVRCGEVSAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCDGTDEAAARIRRVLHNDPATGVMRHADAGYDLAVECAVEQGLNLPMVAATQGKG
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMIP_PICGU
Sequence: MSSILLRSYRHHAKVWTRPSSKSSFIRSLASRSNPTSSFEHVRRVFDDDKYYQDFNNGTLSRKIFSGPRTGLFKNEKLTTPQGLIDFSGQCLTEAQTLVDTMIREAETSDQGKIHYIRRLDQLSDILCRVIDVAEFIRVAHPNSKWTHAAQQTHELMFEYMNQLNTNVQLHTILGNILADKSITSKLSSEEIMVGEYLKQDFERSGIYMEPHTRENFVALTQEISVLGSHFNNGIHELKDYWCEISQQEYEAIDNADLKREIRRFQQKSPRSSRNSVYIPLAGSLPYSILQRCSMESVRRKVWIALHNASEEQISTLNLFLKYRATLSKMLGYESFAHYQLEHKMAKNPENVLTFLENLQRKMVDGENSGLISELESLYAMSNHWKPGASKSDIIHAIQPWDRDYLLHKLQEEKKETQLDDNISEYLSVGTIMSGLSQLFHSIYSIELLPEPSASGETWASQVRKIKVFDNETQSTLGFLYLDFWSPNVLPSHFTIVCSRQLNKDLGEKVEVMKPLVQLDETESHQLPVISLVCNFHQGNSFIGRFAGLETSKPTLLTLDQVDTIFHEMGHAMHSMIGRTKLQNLSGTRCSTDFVELPSVLMESFSKDPRVLGRIARHYSTNELLPHDILAKHQHYRNVLENSETYMQSKMAMLDQVLHGKSIVKQLEMARDDIDSTTMYHSLEKELKVFSDQWSTWHGKFPHLFSYGAVYFSYLFDRAIAEKIWKSLFQNDPWSREAGTTYKEAILKWGGTRDPWHCLADALSNQELSKGDEKAMRIIGGETKDL
What is the function of this protein?
Cleaves proteins, imported into the mitochondrion, to their mature size.  While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial intermediate peptidase, MIP, Octapeptidyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: FLHD_ECOL5
Sequence: MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK6_RAT
Sequence: QLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWKPEDCRRFYREHEGRFFYQRLVEFMTSGPIRAYILAHKDAIQLWRTLMGPTRVFRARHIAPDSIRGSLGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEEGIHCAAETGGPKPA
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase 6, NDK 6, NDP kinase 6, nm23-R6.
What is the protein family that this protein belongs to?
Belongs to the NDK family.