PharMolix/UniProtQA huggingface dataset:
Protein: RN168_RAT
Sequence: MAAPKNSIPSLAECQCGICMEILVEPVTLPCNHTLCNPCFQSTVEKANLCCPFCRRRVSSWTRYHTRRNSLVNTDLWEIIQKHYAKECKLRISGQESKEIVDEYQPVRLLSKPGELRREYEEEISKVEAERQASKEEENKASEEYIQRLLAEEEEEEKRRTERRRSEMEEQLRGDEELARRLSTSINSNYERNILASPLSSRKSDPVTNKSQKKNTNKQKNFGDIQRYLSPKSKPGTAWACKTEHGEDMCKSKETDSSDTKSPVLQDTDVEESMPTHSPQTCPETQGQGPEPLTEMPVPWLCARNAEQCLEGKAEAVSTNPDDSCIVNDGGPRAIVSNSKEAAVKPPTKIENEEYSVSGVTQLTGGNGVPTESRVYDLLVGKEISERENQESVFEEVMDPCFSAKRRKIFITSSLDQEETEVNFTQKLIDLEHMLFERHKQEEQDRLLALQLQKEADKEKMVPNRQKGSPDQYQLRTSSPPDGLLNGQRKNVKDRNSPKQTADRSKSQRSRKGEYWETFESTWKGSVNGTKMPTPRKDSCNVSKRACPLQHRSAQKSILQMFQR
What is the function of this protein?
E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage.  Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination.  Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates.  This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1.  Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair.  H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates.  Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair.  Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites.  Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region.  Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF168, RING finger protein 168, RING-type E3 ubiquitin transferase RNF168.
What is the protein family that this protein belongs to?
Belongs to the RNF168 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to double-strand breaks (DSBs) sites of DNA damage.
Protein: DAPE_ALBFT
Sequence: MPKTLHLAEQLIARPSLTPDDAGCQQIIAERLAPLGFSCETITSGPADFRVTNLWAKRAAAPVKSAQHTTKLVVFAGHTDIVPSGPVQQWRCHPFTPTQFDGKLYGRGAADMKTSLAAFVVAVEEFLTAQPDTALAIGFLLTSDEEGPALDGTVKVCEALQARGERIDYCIVGEPTSLERTGDMIKNGRRGTLSARLTVKGVQGHIAYPHLAKNPIHLVAPALAELVGVEWDRGNAFFPPTSWQISNIHSGTGASNVIPGAVVIDFNFRFSTESTPESLQTRLAAVLERHELDYELAWTLGGTPFLTEPGTLVDAVVDAIKQETGLTTVLSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHINVADIEPLTNIYRRVLENLSAGLSA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MAP22_TALSN
Sequence: MGAKTYEGGDHHEDATNVLSTKSNAVGGKPRGANMLEDGDGEFGSDDDDDGGDGQDSSLAMVNPDDAAKPKKKKRSKKKKNNKKKSGAGAQRQTSPPRVPLSQLFPDGKYPIGQMVEVQDENLRRTTDEEFRYLSRGTITDDEALNDYRKAAEVHRQVRRWIHETIQPGSSLTELAVGIEDGVRALLEHQGLEPGDSLKGGMGFPTGLALNNCAAHYTPNPGQKDIILKTDDVLKIDFGVHVNGWIVDSAFTVTFDPVYDNLVAAVKDATNTGLKCAGVDARVGEIGGFIQEAMESYEVEINGKVYPVKSIRSITGHDILRYRVHGGKQVPFVKSNDQTKMEEGEVFAIETFGSTGKGYLRDGPGVYGYSKEPHAGNVHLPLASARALLKTINQNFGTIPFCRRYLDRLGIEKYLLGMNSLISHGIVQMYPPLVDIAGSYTAQFEHTILINSSGNEIISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2-2, MAP 2-2, MetAP 2-2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YUXL_BACSU
Sequence: MKKLITADDITAIVSVTDPQYAPDGTRAAYVKSQVNQEKDSYTSNIWIYETKTGGSVPWTHGEKRSTDPRWSPDGRTLAFISDREGDAAQLYIMSTEGGEARKLTDIPYGVSKPLWSPDGESILVTVSLGEGESIDDREKTEQDSYEPVEVQGLSYKRDGKGLTRGAYAQLVLVSVKSGEMKELTSHKADHGDPAFSPDGKWLVFSANLTETDDASKPHDVYIMSLESGDLKQVTPHRGSFGSSSFSPDGRYLALLGNEKEYKNATLSKAWLYDIEQGRLTCLTEMLDVHLADALIGDSLIGGAEQRPIWTKDSQGFYVIGTDQGSTGIYYISIEGLVYPIRLEKEYINSFSLSPDEQHFIASVTKPDRPSELYSIPLGQEEKQLTGANDKFVREHTISIPEEIQYATEDGVMVNGWLMRPAQMEGETTYPLILNIHGGPHMMYGHTYFHEFQVLAAKGYAVVYINPRGSHGYGQEFVNAVRGDYGGKDYDDVMQAVDEAIKRDPHIDPKRLGVTGGSYGGFMTNWIVGQTNRFKAAVTQRSISNWISFHGVSDIGYFFTDWQLEHDMFEDTEKLWDRSPLKYAANVETPLLILHGERDDRCPIEQAEQLFIALKKMGKETKLVRFPNASHNLSRTGHPRQRIKRLNYISSWFDQHL
What are the official names of this protein?
Uncharacterized peptidase YuxL.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
Protein: O16A_CONFU
Sequence: ILSLSLLDRSTRCKGTGKSCSRIAYNCCTGSCRSGKCG
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).  This peptide reversibly and selectively inhibits Cav2. 2/CACNA1B (IC(50)=11. 5 nM) voltage-gated calcium channels.  Channel time recovery after toxin exposure is short (about 50 seconds).  In vivo, it effectively and dose-dependently reduces nociceptive behavior in the formalin test and in neuropathic pain models, and reduces mechanical and thermal allodynia in the tail nerve injury rat model.  It also shows significant analgesic effects on writhing in mouse neurotransmitter- and cytokine-induced pain models, though it has no effect on acute thermal pain and interferon-gamma-induced pain.  It also depresses blood pressure immediately after administration, but pressure recovers relatively quickly and completely.
What are the official names of this protein?
Conotoxin FVIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
Protein: DPO3B_MYCLE
Sequence: MDLAKTNVGCSDLKFCLARESFASAVSWVAKYLPTRPTVPVLSGVLLTGSDSGLTISGFDYEVSAEVQVAAEIASSGSVLVSGRLLSDITRALPNKPVHFYVDGNRVALTCGSARFSLPTMAVEDYPTLPTLPDETGTLPSDVFAEAIGQVAIAAGRDYTLPMLTGIRIEISGDTVVLAATDRFRLAVRELKWSVLSSDFEASVLVPAKTLVEVAKAGTDGSGVCLSLGAGVGVGKDGLFGISGGGKRSTTRLLDAEFPKFRQLLPAEHTAVATIDVAELTEAIKLVALVADRGAQVRMEFGDGILRLSAGADDVGRAEEDLAVAFTGEPLTIAFNPNYLTDGLASVHSERVSFGFTTPSKPALLRPTSNDDVHPTHDGPFPALPTDYVYLLMPVRLPG
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO1A1_ACRYE
Sequence: SAGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGSGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGAPGQMGPRGPGERGRPGASGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGPPGPKGNSGEPGAPGSKAKGEPGPTGIQGPPGPAGEEGKRGARGEPGPTGLPGPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGSSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGAPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGAPGPIGNLGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKEGGKGPRGETGPAGEVGPPGPPGPGEKGSPGADGPAGAPGTPGPQGISGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGSSGERGPPGPMGPPGLAGPPGESGREGPGAEGSPGRDGSPGPKGDRGETGPGPPGAPGAPGAPGPVGPAGKSGDRGETGPGPAGPAGPAGARGPAGPQGPRGDKGETGEQGDRGIKRGFSGLQGPAGPPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: TPIS_PARMW
Sequence: MRRPVIAGNWKMHMTCAQARDYMAAFLPQIERAPQDREIVLAPPFTALSTMAAAAEHSVVGLASQNVHWQDHGAFTAEISAEMLLEHGVAYTIVGHSEPRKYFSESDEQINHRARCSQAKGLIPIVCVGESDEQRERGEAERVIRRQIEQGLEGLDANKLVVAYEPIWAIGTGKTCEAAEANRICGLIRSWVGATDLIIQYGGSVKPTNIDELMAMSDIDGVLVGGASLKPDSFARIANYQAI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_METHO
Sequence: MAKEFILGIDLGTTNSVVSVIENGTPKILENPNGKRTTPSVVAFKNGETIIGESAKRQLESNKDSVASIKRLMGTSQTVHLNNKDYKPEEISAMILSYMKDYADKKLGQPVKKAVITVPAYFDNAQREATKNAGIIAGLDVVRIINEPTAAALAFGLNKDKNENQKILVFDLGGGTFDVSLLEMESGTFEVLATAGDNHLGGDDWDHEIVKWMVEQIKSKYNFDPTTDKMAMARLKEEAERAKITLSEQLIANISLPFLAMNENGPVNVELEITRATFESMTEHLLQRTRKPLLDVLSEAKLTWNDINEVLLVGGSTRMPAVQKLVAEVTNKKPNNSINPDEVVSVGAAIQGAILAGEIQDVLLLDVTPLTLGIVVEGDVVAPLIPRNTTIPVTKSQIFSTAVDNQTAVTIVITQGERQLARDNKILGQFNLEGIEPAPRGIPQIEVSFSIDVNGITKVTAKDKKTNKEQTITIQNTSSLSKEEVEKMVKDAEANREADQKKRHEIEVIVKAEQLSNDLEKTLKSEQAKNLGEPQKQELQKEIDEIKELINKKDIEQLEKKITEFEQKMAQAAEFLKKQQGNNNPNTNNDNPQTN
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: Y095_ANADF
Sequence: MPSFDVVSELNLMEVENAFNQARKEILQRFDFKGTSTDLERDKDENVVVKAGSEGRAEAALQVLMEKLAKRGVPLEGLDPQKLEPASGGSVRQLVKLKRGLKQEDAKRIVALMKESGLKVQAAIQGEAVRISGKKKDDLQAAMQAIRTGGLGVPLQFQNFRE
What are the official names of this protein?
UPF0234 protein Anae109_0095.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: FIXA_ESCF3
Sequence: MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTATALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILDIPVVNGVSKIISLTTDTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAVEAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixA.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: MIAA_BLOPB
Sequence: MGPTASGKTSLAIDLKKRKEKIDIISVDSALIYRDMDIGTAKPVAEELKLAPHKLINIRDPVECYSAADFYRDADNEMENIIQSEHTPFLVGGTMLYFKTLLDGLFFLPATNQKIRDDLEYEAKRTGWINIHDLLKHIDPISANKIHLNDHKRIIRALEIFFISGKTWTELKLINNQKLKYRFHQFAVVPSSRDLLYKRIEERFHRMLDIGFEDEVIKLFNRSDLHTKEVKSSISCVGYRQMWEYLSGDINYNQMIIKGICATRQLAKRQLTWLRRWPNLCWLNSDNLSAATDSISKILIEKSI
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SEPF_CALBD
Sequence: MFDNLQRKFLNLIGIEIEEEDKPQEVSKTKDENAKPKHETPKVVTIGKANQTEVTVYNLKLFDEVVKVCDALRENKIVVFNLEQVAEEHIQRIIDFVSGAVYVLDAKIHKVSKKIFVVVPRSIDLEVDEQLKEEFRSKGVFAWLK
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RL32_MYCPN
Sequence: MAVQQRRSSKHRRDKRRSHDALTAQALSVCQKCGKKKLFHRVCSCGMYGDLRVKKAY
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SYT_HELPY
Sequence: MSAELIAVYKDEQIIDLESAKVLGLSDGIKALNGTEPIYFDDSPLALEVIRHSCAHLLAQSLKALYPDAKFFVGPVVEEGFYYDFKTSSKISEEDLPKIEAKMKEFAKLKLAITKETLTREQALERFKGDELKHAVMSKIGGDAFGVYQQGEFEDLCKGPHLPNTRFLNHFKLTKLAGAYLGGDENNEMLIRIYGIAFATKEGLKDYLFQIEEAKKRDHRKLGVELGLFSFDDEIGAGLPLWLPKGARLRKRIEDLLSQALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEYGIKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLRVREFTQDDAHIFCSFEQIQSEVSAILDFTHKIMQAFDFSYEMELSTRPAKSIGDDKVWEKATNALKEALKEHRIDYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNEYNHAEQPVMIHRAILGSFERFIAILSEHFGGNFPFFVAPTQIALIPINEEHHVFALKLKEALKKRDIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETEILSIRDREKQDQYKMPLKEFLNMVESKMQEVSF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_TRIL1
Sequence: MKHKRSDKVAETIHTTISTILSRGLNDPRIGFVTITGVEVTDDLHLARIFFTVIGDEAAKKSSEAGLNSAARFIRHELGKVLKMRYTPDILFKYDHSQEYGQRIDDLLREVGTGNDGNDSEDR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIP1_MYCTO
Sequence: MMFVTGIVLFALAILISVALHECGHMWVARRTGMKVRRYFVGFGPTLWSTRRGETEYGVKAVPLGGFCDIAGMTPVEELDPDERDRAMYKQATWKRVAVLFAGPGMNLAICLVLIYAIALVWGLPNLHPPTRAVIGETGCVAQEVSQGKLEQCTGPGPAALAGIRSGDVVVKVGDTPVSSFDEMAAAVRKSHGSVPIVVERDGTAIVTYVDIESTQRWIPNGQGGELQPATVGAIGVGAARVGPVRYGVFSAMPATFAVTGDLTVEVGKALAALPTKVGALVRAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLILAAINLLPLLPFDGGHIAVAVFERIRNMVRSARGKVAAAPVNYLKLLPATYVVLVLVVGYMLLTVTADLVNPIRLFQ
What is the function of this protein?
Regulated intramembrane proteolysis (RIP) occurs when an extracytoplasmic signal (possibly oxidative stress) triggers a concerted proteolytic cascade to transmit information and elicit cellular responses.  The membrane-spanning regulatory substrate protein (includes anti-sigma factors RskA, RslA, RsmA, and PbpB in M. tuberculosis) is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, this entry), while cytoplasmic proteases finish degrading the regulatory protein, liberating the effector protein (ECF sigma factors SigK, SigL and SigM) (By similarity).
What are the official names of this protein?
Zinc metalloprotease Rip1, Regulator of sigma KLM proteases, S2P endopeptidase, Site-2 protease Rip1, S2P protease Rip1, Site-2-type intramembrane protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CASB_RABIT
Sequence: MKVLILACLVALALAREKEQLSVPTEAVGSVSSSEEITHINKQKLETIKHVEQLLREEKLQDKILPFIQSLFPFAERIPYPTLPQNILNLAQLDMLLPLLQPEIMEDPKAKETIIPKHKLMPFLKSPKTVPFVDSQILNLREMKNQHLLLPQLLPFMHQVFQPFPQTPIPYPQALLSLPQSKFMPIVPQVVPYPQRDMPIQALQLFQELLFPTHQGYPVVQPIAPVNV
What is the function of this protein?
Important role in determination of the surface properties of the casein micelles.
What are the official names of this protein?
Beta-casein.
What is the protein family that this protein belongs to?
Belongs to the beta-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: KUP_CHLPM
Sequence: MTVNARGPEGRTDGAVPEGAGGMKKLAGISLAALGVVFGDIGTSPLYAIRECFHGDYGIAASNANILGVLSLLFWALILIVSLKYLTFIMRADNEGEGGILALTALIIGQSIKKKKDRWVLVSIGLFGASVLLGEAMITPAISVLSATEGLQIIAPAFADMVIPATVVILAGLFLFQHNGTARLGALFGPIILLWFFCLGTLGIIQIIQYPQILEAVMPWYGINFLLNNQLHGFLVLGAVFLAVTGAEALYADMGHFGRRPIRLTWVLFVLPALLLNYFGQGAFLLASPEASSHPFYALVPSWAMIPMVLLATVATVIASQALITGVYSITQQAMQLGYLPRLTVTHTSASHIGQIYVPAANWALMAATIGLVLGFGSSSRLAAAYGASMTTTMLISTILFFFVARDLWKWRPPVLWALVSLFAVVDLSFFGASMSKLFHGAWFPLAVGLLMFTLMNTWKQGRRLLMRQLQDRTLTVDGFLDSLALQEPQRVPGQAVYLTANPDIVPIALLHNLRHNKVLHSEVALFHFSSERVPRVPNSKKVEFVRLKDGFTQVVARYGFLEYPNIRQVLELANALGLNFKPEAISFFLSREKIVADEKTKILPSRKKMFALMARNALSATAYYGLPSGQVIEIGVQVQI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLMA_ACTP2
Sequence: MIQPTVKMPKKSVKERQQQVLEVLIGLLNSEDGMQRVTTERLAKAVGVSEGALYRYFPSKTKMFEALIERIEQTLTGYINASKRKENTTASTVKAILYTVIEFARKNPGVTRILTGHALMFEDDQLKARVAKFFDGLEFQFANILQMSKLREGKTFEDERALAGYLVNFCEGQFLRLVRSNFSYNQHQHFEKQWALIKPLFE
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NU4C_CAPBU
Sequence: MNDFPWLTIIVVFPISAGSLMLFLPHRGNKVNKWYTICICILELLLTTYAFCYNFKMDDPLIQLSEDYKWINFFDFYWRMGIDGLSIGTILLTGFITTLATLAAFPVTRDSRLFHFLMLAMYSGQIGSFSSRDLLLFFIMWELELIPVYLLLAMWGGKKRLYSATKFILYTAGSSIFLLIGVLGISLYGSNEPTLNLELLANQSYPVTLEILFYIGFLIAFAVKSPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLPHAHSMFSPWLMVVGTIQIIYAASTSPGQRNLKKRIAYSSVSHMGFIIIGISSITDPGLNGAILQIISHGFIGAALFFLAGTSYDRIRLVYLDEMGGMAISIPKIFTMFTILSMASLALPGMSGFIAELIVFFGIITSQKYFLIFKILIIFVMAIGMILTPIYLLSMSRQMFYGYKLINVKNFSFFDSGPRELFLSISILIPIIGIGIYPDFVLSLASDKVESILSNYFYG
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HIS2_RUEST
Sequence: MTLLHDLEQTILSRKGTDPDTSWTAKLLSKGPEKCAEKFGEEAIEAIIEAVKDDKAKLASEGADVLYHFLVMLAARDVALDDVLTVLAERQGLSGLAEKAARPKG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPEG_ARATH
Sequence: MATTMTRVSVGVVLFVLLVSLVAVSAARSGPDDVIKLPSQASRFFRPAENDDDSNSGTRWAVLVAGSSGYWNYRHQADICHAYQLLRKGGLKEENIVVFMYDDIANNYENPRPGTIINSPHGKDVYQGVPKDYTGDDVNVDNLFAVILGDKTAVKGGSGKVVDSGPNDHIFIFYSDHGGPGVLGMPTSPYLYANDLNDVLKKKHALGTYKSLVFYLEACESGSIFEGLLPEGLNIYATTASNAEESSWGTYCPGEEPSPPPEYETCLGDLYSVAWMEDSGMHNLQTETLHQQYELVKRRTAPVGYSYGSHVMQYGDVGISKDNLDLYMGTNPANDNFTFADANSLKPPSRVTNQRDADLVHFWEKYRKAPEGSARKTEAQKQVLEAMSHRLHIDNSVILVGKILFGISRGPEVLNKVRSAGQPLVDDWNCLKNQVRAFERHCGSLSQYGIKHMRSFANICNAGIQMEQMEEAASQACTTLPTGPWSSLNRGFSA
What is the function of this protein?
Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms (PubMed:10417725).  Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds (PubMed:14688293).
What are the official names of this protein?
Vacuolar-processing enzyme gamma-isozyme, Asparaginyl endopeptidase gamma-VPE, Gamma-VPE.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
Protein: FM521_ASPOR
Sequence: MANTALIGCTGMVGSFILNNLLAHPSVARVDTISRRTPQAASAAQTKLTTIVSDDTSRWASELSSLTPTPSIFFSAFATTRASAGGFENQYKIEHGLNVEMARAARDAGTKVYVLISSAGADKNAYFAYPRMKAEIEEDVKALGFERTVILRPGLIAGQREESRPMEAAIRCIAGFAGKIHSGLKDGWAQEADVIARAAVNAGLKALEGDVPTGSEKVWVLGGSDIIKYGAGSKN
What are the official names of this protein?
Protein fmp52-1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP52 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.
Protein: VF077_IIV3
Sequence: MSVKVMTHDNMFVGMKEVDHYLAPSDYEDESESELFYESYYSDDIFEDNESDLWVDHEDDPWIEQLDDPVKTPKIIKPYPWMTSPTKSVDKAAQKEKKMPDWWTKPTTVTPTRNEQGILNYSLLLPPSTKKPTQPNKRRKNGGAKPPNSKPLGNPAKPNGVSQQQQGPKRDSTQQPTRLCKSVLKQAKCYFGAQCGYAHRYSDLKECSYGKNCKKIVLVRVNQDGTLHLANKPGAVCNFKHTNEAQQSYLARLPQSTASPKNPRKK
What are the official names of this protein?
Putative zinc finger protein 034R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 077L family.
Protein: RL321_LISMF
Sequence: MAVPARRTSKAKKNKRRTHKGLTTPGLSRDSETGEYRMSHRISPDGTYKGRTIIEK
What are the official names of this protein?
50S ribosomal protein L32-1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ATPE_XANCB
Sequence: MSTIRCDIVSAEQEIFRGEATLVVATGELGELGIAPKHAPLITRLKPGKVVVTTASGEQLDFAISGGILEVQPQVVTVLVDTAIRAQDIDEAAVRKAKEEAERLLANRGDTVDVEQAQRQLAEATVQLQALERLRRTLKH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.