PharMolix/UniProtQA huggingface dataset:
Protein: Y1401_METJA
Sequence: MLIVRKPKKKKDEIEIVKVGGKIEDGIEVKNNQKIFANYKKVGDKYKLYRCRVGDKLIQPSKVLELLKSDKIFILKENEEEIEEVLKSYNLKFDYIELCPFCLLKNIYKRLTRNNRCRYGNLEICINCGINEIKEEVKISEEFIEKFLKRFKDVDKVLSLLRIRNPLDKPELTRYDIITGSEEDKIENYKIDELDIPEELKEIIKSRGIEELLPVQTLSVKAGLLNGDDLLIISATSSGKTLIGELAGIKNLIKTGKKFLFLVPLVALANQKYLEFKERYEKLGFKVSLRVGLGRIGKKVDVETSLDADIIVGTYEGIDYLIRTKRLKDIGTVVIDEIHSLNLEERGARLDGLIGRLRFLFKEAQKIYLSATIGNPKELAKQLNAKLVLYNGRPVPLERHIIFCKNDFAKLNIIKEIVKREWQNISKFGYRGQCLIFTYSRKRAEYLAKALKSKGIKAEFYHGGMEYIKRRKVEDDFANQKIQCVVTTAALSAGVDFPASTVILESLAMGADWLNPAEFQQMCGRAGRKGMHEIGKVYLLVEIGKKYHAKMENTEDEVAFKLLNAVPEDVKVEYNEDEEEEQILATISAGITNRYDIDRVPYIGRAFSLNKILSNLESYGMIKANNDVKLTNYGSAVAISFLYPKVAEKIKEGIIENKEIIKLITEIMPFENVYLSNNLKIKLSKILNINVPSRFFDALEVIREGMEKIKDKKLKEDLTLIIMEFEGVEVEEKILEMIINLRISGKTPGQISKTLYEEFKIQTYSGDIYYYLEQLLNLLDATERIARIFNKRYAEKVKELKEKIENPK
What are the official names of this protein?
Probable ATP-dependent helicase MJ1401.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: ALR_NITOC
Sequence: MNFPQAIIDASALRHNLQRVRELAPRSQIMAVVKADGYGHGLTRVADVLVAADAFAVARLEEATALRQAGHRCPVVLLGGISDKEQLQLAAAHRLTLVVHEFAQLDLLERVRITSPLPVWVKADTGMHRLGFPPQVVAKAIARLRCCPAVASVVGLMSHLASADESEDFLTPIQLQTFEGIAAPGLLRSMANSAAVMVYPYAHFDWVRPGLMLYGASPFAHGTGAAVGLKSVMTLQTRLIAIHHLRPGDSIGYGATWVCPEAMTVGVAALGYGDGYPRHAVSGTPVLVNGRPVPLVGRVSMDMITLDLRTQPKAKVGDPVIAWGPNLPVEEVARHATTIPYELLCQVTGRVPRTME
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: V_NDVU2
Sequence: MATFTDAEIDELFETSGTVIDSIITAQGKPVETVGRSAIPRGKTKALSSAWEKHGSVQSPASQDTPDRQDRSDKQLSTPEQVTPHDSPPATSTDQPPTQAADEAGDTQLKTGASNSLLSMLDKLSNKSSNAKKGPMVKPPGRASSTSDSTAGESTKPRKQSRETAEPGQGRPWKPGHRREHSISWTMGGVTTISWCNPSCSPIRAEPRQYSCTCGSCPATCRLCASDDVYDGGDITEGK
What is the function of this protein?
Protects the virus against cell antiviral state by blocking host interferon signaling.  Mechanistically, targets host phosphorylated STAT1 (phospho-STAT1) for degradation, thereby inhibiting the interferon alpha signaling pathway.  Plays a role in the inhibition of host apoptosis.  Interacts with and down-regulates the expression of host TXNL1.  In turn, inhibits TXNL1-induced apoptosis through the BCL2-BAX-caspase 3 pathway.  Inhibits host apoptosis also by negatively regulating host CacyBP/SIP.  Promotes viral replication by activating the extracellular signal-regulated kinase (ERK) pathway.
What are the official names of this protein?
Non-structural protein V.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: EXO1_DICDI
Sequence: MGISGLLPALSPVTKAIHVKDYANKRVAIDGYSWLHKGAYSCSQEIVLGIPTRNYINYFISRIKMLISYKVIPVVIFDGGPLPNKKLKEQERLRHREEYKNKAKAYLLEGNKSQANICFQKAVDITPRMAFLLIKELRALKVEYLVAPYEADAQLTYLSITGQVDAIITEDSDLVAFGATHIIFKMDKYGYAQEIKTEDLGSCKKDGYDFIDFNQTMLRQMCILSGCDYLPSLSGMGLKTSFKLLKQHRDIEKVFKYLKREKSNFSQEYEQQFYKADFTFKHQRVFDPVSRILTTLLPLPTIIDSRFLNDNNNNTNDGDSNGDGSSGGSGSGGGFLDFIGPVIDDEIAEKIALGIIDPETHEQFDKTQPYPKNTFTPQPKKLLSPISFNTKEFKNQTNNNNNNNNNIKSNNGTNNKNGMILNEGKLVQKGRNLNDQFTFASNKITQYMTTTTTTTTTTTTTKNNNNNQKQQPMIEDDTGYDFQIDSFEIDDCLNDDDDDESIILSNNLNNQENVLESDCEFDDDDDQRGIDVDDSEKKDSFVLDSDYEDEKEEEEVKSSTFNSSSSISSGNSSKIKKTLVSSKFFVSSESSVLESDDDDGGDDDDDSFNHNQNFSSSGNNIQPNSNIFHNGELSSYGYQKNQKNFKNVNSNSSSNSSNSSNSSSGNSNSGNRIFNSGNSSNKNNTNGGIVKSTLLSSNDRVSLNFFDQFQFDGKKKQSILVSQSRKSFSSPTLSNNEDYDSSFVSSTIPSSIGDDYDQMNSCSNNNNFNYNNSSNFNNNNINNSNNNRNSGFSGFLKRKSSSQTAAPTTPTTPTTPKTSSSSSSTLTNSTITTEHSSYILKKPKYQATSNSPISTLDSSQNYNDQSFISKKAHSFSSLDSDLIFKEDDVDNLIFNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNDNNNKITTPSNKSFNSIVLTTTSATTSITQQDNEIYTTPKKKLPSTPISSSSNDIISKYFSSPSKVGPKSEGAPPTPVNLEGMSLRSVLSLRYQQTMASSPTK
What is the function of this protein?
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity.  Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch.  Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment (By similarity).
What are the official names of this protein?
Exonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYQ_XANC5
Sequence: MSETLATDATAPAEKKDFIRQIVREDLASGKHTVIRTRFPPEPNGYLHIGHAKAICLDFGLAAEFGGLCNLRLDDTNPAKEDPEFVVAIQDDVRWLGYEWAQLRHASDYFQVYYLAAQKLIRDGHAFVCDLSAEQVRQYRGTLTEPGRNSPFRERSVEENLELFARMRAGEFPDGARTLRAKIDMASGNINLRDPALYRIKHVEHQNTGNAWPIYPMYDFAHSLGDAVEGITHSLCTLEFEDHRPLYDWCVDKVDLAGHPELLQPLLDKGLPREAAKPRQIEFSRLNINYTVMSKRKLTALVEEQLVDGWDDPRMYTLQGLRRRGYTPAAMRLFVDRVGISKQNSLIDFSVLEGCLREDLDAAAPRRMAVIDPLKLVLTNLPEGHTETLQFSNHPKDESFGTREVPFARELWIEREDFAEVPPKGWKRLVPGGEIRLRGAGIARVDEVIKNADGEIVELRGWLDPESRPGMEGANRKVKGTIHWVSAVHAVEAEIRLYDRLFSVEKPDDESEGKTYRDYLNPESKRNVRGYVEPSAAMAAPEQAFQFERSGYFVADRRDHSAATPVFNRSVTLRDTWAK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_STAA1
Sequence: MNLIAAAIAIGLSALGAGIGNGLIVSRTVEGVARQPEARGQLMGIMFIGVGLVEALPIIGVVIAFMTFAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: M1_I77AF
Sequence: MSLLTEVETYVLSIIPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVAGQARQMVQAMRTIGTHPSSSAGLKNDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: FETP_POLSJ
Sequence: MARMVKCIKLGREAEGLDFPPYPGPLGKRLWEEVSKEAWADWMKQQTMLVNENRLNLADARARQYLARQMEKHFFGDGADAVQGYVPPSA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: GLPB_YERPA
Sequence: MKFDVIIIGGGLAGLACGIRLAEQGKYCAIVSSGQNALHFSSGSLDLLAKLPDGQAVSQPLSALSALAELAPEHPYSKMRNITQLDELVQEAEALLRRCGLDIVGSSAENHLRLTPLGSCRPTWLSLADIPVAPLNGPLPWQRVAVIGIEGFLDFQPQMVASALQDQGIDATADYLHLPALDRLRDNPSEFRAVNIARILDLPENRQPLADELSRLSSTAEMILLPACIGLDKSAPLDALRAVVGKPIQLLPTLPPSLLGMRLHQALRHRFQQLGGLVMPGDAVLRAELVDNRITGLYSRNHGDIPLRAAQMVLASGSFFSNGLVATFDKIYEPILDLDILSLPHRADWSHSNLFAPQPYLQFGVNTDNHLRPLRGGVALENLHAIGAVLGGYDPLQQGCGAGVSLTSAVFVAEQIISEMAVTL
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: CLD11_RAT
Sequence: MVATCLQVVGFVTSFVGWIGIIVTTSTNDWVVTCSYTIPTCRKMDELGSKGLWADCVMATGLHHCKPLVDILILPGYAQACRALMIAASVLGLPGILLLLTVLPCIRMGHEPGVAKYRRAQLAGVLLILLALCAIVATIWFPVCAHREITIVSFGYSLYAGWIGAVMCLVGGCVIVCCSGDAQSFGENRFYYSSGSSSPTHAKSAHV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-11.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: DCUP_CHLCH
Sequence: MLKNDLFLRALKRQPCSRTPIWVMRQAGRYLPEYRAVREKTDFLTLCKTPELATEVTIQPVELVGVDAAIIFSDILVVNEAMGQEVNIIETKGIKLAPPIRSQADIDKLIVPDIDEKLGYVLDALRMTKKELDNRVPLIGFSGAAWTLFTYAVEGGGSKNYAYAKQMMYREPQMAHSLLSKISQTITAYTLKQIEAGADAIQIFDSWASALSEDDYREYALPYIKDTVQAIKAKHPETPVIVFSKDCNTILSDIADTGCDAVGLGWGIDISKARTELNDRVALQGNLDPTVLYGTQERIKIEAGKILKSFGQHNHHSGHVFNLGHGILPDMDPDNLRCLVEFVKEESAKYH
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6C_OENPA
Sequence: MDLPGPIHDFLLVFLGSGLIVGGLGVVLLTNPIFSAFSLGLVLVCISLFFSLSNSYFVAAAQLLIYVGAINVLILFAVMFMNGSEYSKDLTLWTVGDGITSLVCTSIFISLITTILDTSWYGIIWTTKSNQIIEQDLIGNSQQIGIHLSTDFFLPFELISIILLVSLIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LIFO_VIBVU
Sequence: MKKTALTIITIALGSLGAVYFLPSEPAAQKDIRATSQHDTSVDNTSAKAFLDYSLSTLGEKPLQTITQDVVREERALGELQLDEQLFALYLRYKQALADLDIEITGSDIISLETLHQAILDLQREYFSAQQIDLIFGEENQLRALALEKARLSEQGYSAEEQKQLWRDHLALQPEYVQESDANRRLMSELAQGEDAQTTYLKRVELVGEAGAQRLEVLDQNRAEFDRVFQHYLVQRSAILDDLGLSDEQKHKQITMLRETSFDAKQWRRIEALERIADGG
What is the function of this protein?
May be involved in the folding of the extracellular lipase during its passage through the periplasm.
What are the official names of this protein?
Lipase chaperone, Lipase activator protein, Lipase foldase, Lipase helper protein, Lipase modulator.
What is the protein family that this protein belongs to?
Belongs to the lipase chaperone family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: POL_VILV2
Sequence: MAKQGSKEKKGYPELKEVIKATCKIRVGPGKETLTEGNCLWALKTIDFIFEDLKTEPWTITKMYTVWDRLKGLTPEETSKREFASLQATLACIMCSQMGMKPETVQAAKGIISMKEGLQENKEAKGEKVEQLYPNLEKHREVYPIVNLQAGGRSWKAVESVVFQQLQTVAMQHGLVSEDFERQLAYYATTWTSKDILEVLVMMPGNRAQKELIQGKLNEEAERWVRQNPPGPNVLTVDQIMGVGQTNQQASQANMDQARQICLQWVITALRSVRHMSHRPGNPMLVKQKNTESYEDFIARLLEAIDAEPVMDPIKTYLKVTLSYTNASTDCQKQMDRTLGTRVQQATVEEKMQACRDVGSEGFKMQLLAQALRPQGKAGHKGVNQKCYNCGKPGHLARQCRQGIICHHCGKRGHMQKDCRQKKQQGKQQEGATCGAVRAPYVVTEAPPKIEIKVGTRWKKLLVDTGADKTIVTSHDMSGIPKGRIILQGIGGIIEGEKWEQVHLQYKDKMIKGTIVVLATSPVEVLGRDNMRELGIGLIMANLEEKKIPSTRVRLKEGCKGPHIAQWPLTQEKLEGLKEIVDRLEKEGKVGRAPPHWTCNTPIFCIKKKSGKWRMLIDFRELNKQTEDLAEAQLGLPHPGGLQRKKHVTILDIGDAYFTIPLYEPYRQYTCFTMLSPNNLGPCVRYYWKVLPQGWKLSPAVYQFTMQKILRGWIEEHPMIQFGIYMDDIYIGSDLGLEEHRGIVNELASYIAQYGFMLPEDKRQEGYPAKWLGFELHPEKWKFQKHTLPEITEGPITLNKLQKLVGDLVWRQSLIGKSIPNILKLMEGDRALQSERYIESIHVREWEACRQKLKEMEGNYYDEEKDIYGQLDWGNKAIEYIVFQEKGKPLWVNVVHSIKNLSQAQQIIKAAQKLTQEVIIRTGKIPWILLPGREEDWILELQMGNINWMPSFWSCYKGSVRWKKRNVIAEVVPGPTYYTDGGKKNGRGSLGYIASTGEKFRIHEEGTNQQLELRAIEEACKQGPEKMNIVTDSRYAYEFMLRNWDEEVIRNPIQARIMELVHNKEKIGVHWVPGHKGIPQNEEIDRYISEIFLAKEGRGILQKRAEDAGYDLICPQEISIPAGQVKRIAIDLKINLKKDQWAMIGTKSSFANKGVFVQGGIIDSGYQGTIQVVIYNSNNKEVVIPQGRKFAQLILMPLIHEELKPWGETRKTERGEQGFGSTGMYWIENIPLAEEEHNKWHQDAVSLHLEFGIPRTAAEDIVQQCDVCQENKMPSTLRGSNKRGIDHWQVDYTHYEDKIILVWVETNSGLIYAERVKGETGQEFRVQTMKWYAMFAPKSLQSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQALVERTHQTLKNTLEKLIPMFNAFESALAGTLITLNIKRKGGLGTSPMDIFIFNKEQQRIQQQSKSKQEKIRFCYYRTRKRGHPGEWQGPTQVLWGGDGAIVVKDRGTDRYLVIANKDVKFIPPPKEIQKE
What is the function of this protein?
Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions.
What are the official names of this protein?
Gag-Pol polyprotein.
What is the protein family that this protein belongs to?
Belongs to the retroviral Pol polyprotein family.
What are the subcellular locations of this protein?
[Matrix protein p16]: Virion. SUBCELLULAR LOCATION: [Capsid protein p25]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p14]: Virion.
Protein: KPRA_HUMAN
Sequence: MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD
What is the function of this protein?
Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.
What are the official names of this protein?
Phosphoribosyl pyrophosphate synthase-associated protein 1, PRPP synthase-associated protein 1, 39 kDa phosphoribosypyrophosphate synthase-associated protein, PAP39.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
Protein: MIAA_TROW8
Sequence: MLSLDAARDFNGHIVNADSMQLYRDMDIGTAKLSHSARQGIPHHQIDVIDPSSEASVARYKLSAQTCIKHIHALNSIPFLVGGSGLYVSSVVHNLQFPPTDGRVRKLLEDEADKSGIGVLHDRLLKLHPGFTVSRGNRRRIIRALEVAYITGRSPNPVLPLQNRANNFIVINLICDKGTLDIRLQKRVESFYDNGLIDEVRLLQEKYVLGRTAAKAIGYKQAIMYLAGEISCADAKDSTLQETIRLANKQIKWFRRYSGQHIVDTTDMSVAYEQIRSILNKSFRIS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SYR_STAAW
Sequence: MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE5_HPV51
Sequence: LYRHIVTIAVFIILLFVLCLCVCLVLCCLLPLLLSQYVFAAALLLILCFWFVVATSQLTTFFVYLIFFYLPCLLLHLYTFLLLQ
What are the official names of this protein?
Probable protein E5.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E5 protein family.
Protein: EREG_RAT
Sequence: METFPAAWVLALLCLGSHLLQAVISTTVIPSCIPEESEDNCTALVQMEDDPRVAQVLITKCSSDMDGYCLHGHCIYLVDMSEKYCRCEVGYTGLRCEHFFLTVHQPLSREYVALTVILVFLFLIVTAGSMYYFCRWYRNRKSKKSREEYERVTSGGPGLPQV
What is the function of this protein?
Ligand of the EGF receptor/EGFR and ERBB4.  Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9990076).  Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357).
What are the official names of this protein?
Proepiregulin.
What are the subcellular locations of this protein?
[Epiregulin]: Secreted, extracellular space. SUBCELLULAR LOCATION: [Proepiregulin]: Cell membrane; Single-pass type I membrane protein.
Protein: EX7S_STRPB
Sequence: MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKELQKTLQAAEKTLVKVMQADGTEVDMDD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_PSYIN
Sequence: MINNTEIRQNWTVAEVDQLFEMPFMDLVFQAQTTHRANFPLNEVQVSTLLSIKTGACPEDCKYCPQSARYNTGLAKEQLIEVAKVVKAAKEAKATGSTRFCMGAAWKNPKQRDMPYLLDMIKEVRALGLESCMTLGMLDNNQAEQLSNAGLDYYNHNLDTSPEYYDKIITTRTYQDRLDTLENVRNSGMKVCSGGIVGLGEAGSDRSGLLVQLANLPQQPESVPINKLVKVKGTPLENADDLDDFTFIKTIAIARLLMPKSHVRLSAGRDDMNEQTQALCFMAGANSIFYGCKLLTTANPDENSDTRLFEKLGINKEAINFSPSEAEKKVDAAIVRFNEKDELFFDATSKA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: UREG_PSEPG
Sequence: MQSYQQPLRVGVGGPVGSGKTALLEALCKAMRDHYQIAVVTNDIYTKEDQRILTEAGALEPERIVGVETGGCPHTAIREDASMNLAAVEALARKFGNLEVIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVGASLEVMERDTQRMRPQRPWTFSNLKKGEGLQAVIDFIVERGMLGVRG
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_STRCO
Sequence: MAVKIKLKRLGKIRSPHYRIVVADSRTRRDGRAIEEIGKYHPTYNPSVMEVDAERVAYWLGVGAQPTEPVLAILKKTGDWQKFKGEPAPAPLLQPAEKAARPSFEAIGGEDEGKGEAITQKKKADKKDEAAAESSASEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PQE1_CAEEL
Sequence: MFNGGYGSGNSFNLQNYAPIDPMTGIPGFGPSQNAQQQQQQASAPGTSSGGPSQAVSGASSGASMKTEPVARQVSTAQMKRDLEQAAVYVPTPIPEGSTQPQQRQQQQSQPQARQMSTQQAANLRKNAAAAGTPPKQAMQGASREQGNAHQPTAGQIPQSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQVQNAPQRIPQHVPMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQTPARGRPANAQLAQNAQQRNPQQVPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAPVQGPHRGAPQMAQQPGPHGAAQHPSSGTVAPMHITSLPGNHPLNRTHLLFNRQVVPALDIRNLIAQHRLMVDDFVRAQICYRLPENHQDYWPPGGHPIPMQQQQMRQGAGLPNMAMPPPPLMRHPGPHQNPIHAMQSMQVQPPLSPDQMNMQMFQQRALMMQQQAMQMQMQNPPPVHQQPPPQQPPQQQRQKQQRSQPAPARVPPQVPSQVPVTGGVAADEPPPPCSYSPVAQSSESKIEPVDVKPRVAPVPPQVPVTPTKPVITNNKKKRIDVVTLDEDAPRRVQVKQEIPEVSSTSDATKSDAAPTARGAVRIKQEVESDVAPNTILISAKKFERMKAEAEDKEDMKKKIAALQEALFNIQEERRVEKEIAAFATTNQAVPQNQPASSVQIAQVSTSESDAPGTSEAAATETMTSPKTKNNVIVETEGEQEEDEDEIPIKKSKKRRAKIVSNDEEEEPVRHPKRRSDEKREKRHVSYAESDDDMPVVKKKRRNQSPEDPEYSAASPSEDEDDDIGSFVVSDNEDDDADSFVVGDDEPIEYEEEDEDDMIERRSSRKRRSDSRSKKSATPTDRRRSRDTPTGSRSMRSTSPNDRRKSRETPPGNRSMRRTSPSDGRKSRDTPTASSSMSSSTLSYCKKSKETPMSYEEIEQQKKAKRQRNCKTREENRERKRLAQLEELESSETTGVRRTLRSTQDNSDPLDASLATTIEEFRKTKKKDAKSSENRAKEKQKPMNKRPTSSASVDSNDDGVHIPAKRMAHASSVPGPSRSKPPMIGAVKNRPNHTEMLDKRNKESEEKRRKDRDELERLRNKKHTTEEEKIKMARLQNALKVVGKAAGLKATVKKELTGSPAKKQKPAPAVPKILDFSVGRTFTAIRQTAIKLVFDTFLERDSPNAAREAQEFELSIAKQYTDGQKYRINIGHKVAALRKENTSGILEVNKNAVSHDKILAGGPKDNCTVARGRKTHVDHRQLSIEKLHPLLLQFKLTTSELETNAYPMRRDGSTKAVSIADTVYTQNKKMFLDDYDMSRNCSRCNKEFKLSPNGTMIRSTGICRYHNRGVAINGKRDTFRKRYSCCNEEFNVALGCKFSDVHVTDQLFKKELSTFVSTPVPVPNDQRSTRVYALDCEMVYTIAGPALARLTMVDMQRNRVLDVFVKPPTDVLDPNTEFSGLTMEQINSAPDTLKTCHQKLFKYVNADTILIGHSLESDLKAMRVVHKNVIDTAILFRSTRDTKVALKVLSAKLLHKNIQGDNEDAIGHDSMEDALTCVDLIFYGLRNPESIAIREANTNC
What is the function of this protein?
Putative RNA exonuclease which protects neurons from the toxic effects of expanded poly-Q disease proteins (PubMed:12486229).  It is unknown whether this is via participation in the pathogenic mechanism underlying poly-Q-induced neurodegeneration or if it is by acting as a genetic modifier of the age of onset or progression of neurodegeneration (PubMed:12486229).  Regulates gene expression in neurons (PubMed:22870397).
What are the official names of this protein?
Putative RNA exonuclease pqe-1, PolyQ enhancer protein 1.
What is the protein family that this protein belongs to?
Belongs to the REXO1/REXO3 family.
What are the subcellular locations of this protein?
[Isoform a]: Nucleus. Note=Forms aggregates in the nucleus.
Protein: GATB_AQUAE
Sequence: MNEKYEAVIGLEIHVQMDTKTKMFCGCKVEFGAEPNTNVCPVCLGMPGALPIVNKRAVEYAIRASLALNCEVHEESVFARKHYFYPDLPKGYQISQYEKPLATNGWVELNLPNGEKKKVRIRRLHIEEDAGKNIHEGDKTLVDLNRAGTPLMEIVTEPDIRTPEEARLFLEKLRNIMRYAGVSKADMEKGQLRCDINVSIRPKGSKEFGTRVEIKNVNSFRFVQKALEYEIERQINVVEEGGEVVQETRTFDPQTGKTYPMRTKEEAEDYRYFPDPDLVPLKVKKEWIEEIKKNMPELPDQRFERLIKEYGLSEYEAGILVNHKEVGDFFEEAVRHFKEPKGIVNWLINDLLGLLRDKGISIEESPVKPEHLAELVKLIKEKVISTKIGKEVIKEMVETGKTPSQIVEEKGLKQITDENQIKELVKKIFEKHPKEVERLKQGEEKLIGFFVGQVMRETRGKANPQVVNKVIRELVKEV
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.