Protein: FYV1_DICDI
Sequence: MAESFQQLGVGSKSNERSFFSKFFGTDDSQKDFGPLPEIEYSDEQRFNPYPAIYEKKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNGNGNRSNSSLNNSNNNNQVRRTHSPSVSNKSDESNTTNTNTNITTNTNITTNTNTNTNTNSTNNDTSSNVTQQQLLTNLGQSKIISALKTKFQRPLPPVDDKKFWMPDHSSAVCYECSEEFTTFKRRHHCRLCGQIFCWKCSQKTLTDGKGERVRVCNFCYRRYMAPDDLDMEGYHYDPITGTVISLITNNDDGTNLNNGNGLIKLDGSTHNMNVSLGNSGDNSSFVQSPNNNFSQSPTFSQQQQQQQQQQQQQQQQQQQQQQQQTTGVMSGLNPFSNSTLLFGRNNNNNNQQQQQPIIEEDKQYYGDINTSYNNSYFNNNGFNNFNNEHYNNTNFNATSLNLNSQLHSNLLANTNGELFYDNSQHSISNYGNLDHHQQQQQSNSHGSLSATPSNTPSGLISPIVGAPSILDPNKMIFYSDQEGNYDNLDDYETSSSDGSDNDNEDNHLKSSHSSANDLGTSNTVSTGESNSESKLSSSSNDISIHHHHYHHHHHHSHGNLLKSNSLTPLNLNNNNIIINNNNINNNNNNDNGNDDNNNNNNDNNNNTTIEVDPRHSMPSKTSNTSFSMASLPSIFKLPTIGRNNNNNNNSGSGNSQYLSANSNASNSISPPNSARGSSSNPNSMTPTPTLSSSFSNLPNAETSPPSLVKAKQQQQQQQQQQQQPQPVLQPTIHHPLKTSLPMFSTQSPPPPTNQLAQSTSMAPPPSIFSPLGKLQALSHPSSSSNNQQQQQPQIVKPIIIAPNSLFFSDPSIVSLKSHPKTTNKTKFLEKYPLPKKYYESTENIIDTFGFKRTPSTEGNLLSQMLATSKQKEFDEKERLKISNNPQMSVYIQHINNLVSEQLEKNNIDLSWRSIIIDLTKKATDNVKIFVRKGDKMSTNEYIKIKKIPGGNKSECNYVDGVVMTKILTHKKMKDKFINPKILLLSCSVEFQRVENKFLYFDQLLQQEKEYLRILVSKIAERKPDLVLVEKTVSRHAQDFLLDAGISLALNVKPKLLERLGRCLGGEVLPTLDIIYNNNSNNNNSNSIQLQQQQNSNSPASLQNSTTTTNNNNNNNNNSTTLGSCGQFKVITYSEIGLKEKEILGKKTLMYFEKCPVELGATIIIRGEDLAVLKIIKKILKLSIFSMHNAYLELKYLNDQSSTSNLLFVNNNGQNLSCSPQIKFPLPKTYPTIPWKYQFTSQHIPVKKALLTSFYKPHSDFGQQQSVIQWTSDDEVLGIGTSDAFKHCDMKFPIENESIYDHQSIVFSHSIFCNSNQCIPFEIHAIDYYTDNDLTLGEFLSKFCFSLHICNIKECNRPLIEHERTFMNSTTRINICVQKTQTIQDRPTNSSPAQQRNQPVQRAGINVINLCKICNKFSPESPMSEEAWEMSFGKFLELCFFGFLPIKTGISPECSHNNAKDHISYFYYQDLAAIFSYEPLPSLELSLPPKNLKATYTEKQRQSVRAKELEIMNQCANQVYSAIHERLYEIGQENQGDRVQELIPSLVQEKQLICSKIESLLLLPESAHKSNDQIINLTKLLYANFMTWNSQLTGLIDSTSYQRSKRNVQQQQQQQQHQQSQQPQPQILIGGDVYSDSHLHTDSVKKINSKQHSHNTILLQSIQSNQEQQLEQQEEFEINVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTIDNKSENENENKNENKNENENENENKNENKNENENENKKENENQLEIKNENNDSGEEITNNNNNNNNNNNNNNNNNNNNNNNIDNNNNKDENISSTPLLSPSSVLGVSNSGINQAFLNAPNNTYNSVEQDLTLPLNHQSLNFAVGGLVSPGSSSGGLPVGSVPNSSSMPSIHNGGSGNIPSNLVGSASGLSTNYSPNALKDPKKLKIIDTIAGIVSSISQTRILGPTMPYLLLESTDNVALFENEPSTTIAYTLSSSDFKIALNSLLDEEWKRISEIEKQYELQQQQQQDSQDLESSSQQQQQQQQQQQEQQEQPSLPTPSHPLSQSMNFSPSSLLKISSSSLPKDNNNSSENKPNSETNDIVRSRGSVKLSGSPISISPLSNAFEKRKSTSLSSSANNSPISSILEKEKKLKQQSPSLSNSLSGQTIINNNQQQQQQQQPSPIIIDEKDDRNTEKSSIIETDSIIEDLNINQDESNITNEDGGKIGDYESELLYDHHQQGDSENNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNNEQQINNSDTEGDSDSIKSSNSNIYSEKNIKLSKLMVSTQRKEIRSRFKFEKNGYELNIFCSSYYPVQFHALREYMCGDQEFIQSLTRSKIWNAKGGKSGSSWNKTLDDRFILKQVSRIELESFLDFAPLYFEYICKSFLNQIPTALCKILGVFTVRWKDSNGKALKKDLIVMENLFHSKCISKTYDLKGSLRGRLVKNESEVLLDENLLQASFASPICLGEYDKTRVALAVWNDTAFLSSLNVMDYSLLSGIDNQSNQLVVGIIDYMRKFTWDKALEMKVKQSGIMGGGGKVPTVISPKQYKLRFRDAMWLYFTLSPDKFTKVKHLMPYEKKKNNNNNYNYNNFNNNNFNNNNNISNNGNGNINQRQVQQINK
What is the function of this protein?
Dual specificity kinase part of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate.
What are the official names of this protein?
1-phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase, FYVE finger-containing phosphoinositide kinase, PIKfyve, Phosphatidylinositol 3-phosphate 5-kinase type III, PIPkin-III, Type III PIP kinase, Serine-protein kinase PIKFYVE.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Cytoplasmic vesicle, phagosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein.