PharMolix/UniProtQA huggingface dataset:
Protein: EF2_CALJA
Sequence: MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAERAKKVEDMMKKLWGDRYFDPATGKFSKSASSPDGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNTSRPSQVVAETRKRKGLKEGIPALDNFLDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C- terminal cleavage product.
Protein: TPIS_HAEDU
Sequence: MARRPLVMGNWKLNGSKAFTQQLIAELKTELAEITGCDVAIAPPVMYLSEAEIALAGQSTIRLGAQNVDINTQGAFTGDISTAMLQEFCAKYIIIGHSERRTYHAESDQFIAKKFAALKTAGLTPVLCIGETEAENEAGQTQQVCARQIDAIINSLGVEAFNQAVIAYEPIWAIGTGKSATPAQAQAVHAFIRQHIAEKSQAVADQLIIQYGGSVNDTNAAELFSQPDIDGALVGGASLKATAFAEIVKAAEKAKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_ECOL6
Sequence: MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDILEWRVDHYADLSNVESVIAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: EI3D1_DROPE
Sequence: MSETINTAAQFPSFEKPTVQFNERGWGPCELPDTFKDVPYQPFSKNDRLGKICDWTSTSNNDKKYQNKYASSFGTGNQYSYYHEEDETTFHLVDTARVQKPPHQRGRFRNMRGRGGRGRNPRGGLNNHHHHGMTTLNGKNVKARDTRRGMGKKFGHRGPPPKMRESSVAVRADWASIEEMDFPRLIKLSLPNIKDGVDIATCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTTDDPVIRRLSKTVGNVFATDAILATIMCSTRSNYSWDIVIEKVGDKPPTDDDSSCNSPRNLAIEATFINHNFSQQVLKTGDQEAKFKFEEPNPFISEDEDIQVASVGYRYKKWELGSDIVLVARCEHDGVLQTPSGEPQFMSIKALNEWDSKLANGVEWRQKLDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNAWGVLRCIIDLVMKQKDGKYLIMKDPNKPIIRLYDIPDNTFDSDDSDDGEGDDGEGFQQVYNYANNSNKI
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D-1, eIF3d-1, Eukaryotic translation initiation factor 3 subunit 7-1, Eukaryotic translation initiation factor 3 subunit p66.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_BEII9
Sequence: MRLILLGPPGAGKGTQSERLREQCKIPQLSTGDMLRAAVKAGTPIGLKAKAVMDAGGLVSDDIVVGIVADRIEEPDARNGFILDGFPRTVKQAEALTTMLHEKKMDLDAVIELVVDENALLARIEKRAKETLAAGGTVRADDNPAAFKTRIDTYREQTAPVSAYYASQGVLKTVDGMADIDTVTAAIDKILKA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFB_ECOLC
Sequence: MKITLSKRIGLLAILLPCALALSTTVHAETNKLVIESGDSAQSRQHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVITP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: Y2501_STAAW
Sequence: METLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKDHFTVVAVDRRDYGESELTEPLPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSEFEIRQYTHSDITLDDFTKYSDKITLLNGTDSRGSFPQDVNFYINKETSIPIVDIPGGHLGYIQKPEGFADVLLNMWG
What are the official names of this protein?
Uncharacterized hydrolase MW2501.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: TET5B_RAT
Sequence: MMPSESGDESLEQPAAQVGTGAASAVATAGAAGGGPDLEASSASLGRHQSRLSWPQVKRLDALLKEPIPIHGRGNFPTLSVQPQQIVQVVRSSLEEQGLHVHSVRLHGSAASHVLHPESGLGYKDLDLVFQMDLQSEASFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKVCTDLDRWSLISLSNKSGKNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQCSSTPMSEAFHPTVTGESLYGDFAEALEHLQHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDPVEQRRILERYLEAHFGGAEAARRYACLVTLHRVVNESTVCLMSHERRQTLDLITMLALQALAEQGPAAMAALAWRRPGSDGVVPATVNYYVTPMQPLLPRAHSYPTWLPCN
What is the function of this protein?
Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group in an ATP hydrolysis-dependent manner.  May be involved in maintaining the translation efficiency of at least some genes through preventing degradation of their mRNAs.  Prefers RNA molecules that are adenosine-rich close to 3'-end.  In addition, may inhibit cell proliferation and cell cycle progression through ubiquitination of beta-catenin/CTNNB1.
What are the official names of this protein?
Terminal nucleotidyltransferase 5B, Non-canonical poly(A) polymerase FAM46B.
What is the protein family that this protein belongs to?
Belongs to the TENT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MNS4_ARATH
Sequence: MDSNFKWLLFAILISLTFSGFVLHHGVLAESVKPDEAKQLRDEVRGMFYHAFDGYMNNAFPLDELRPLSCQGEDTLGGYALTLIDSLDTLALLGDRERFTSSVEWIGKNLQFNINKTVSVFETTIRVLGGLLSAHLIASDYATGMRIPSYNNELLVLAENLARRMLPAFDTPTGIPFGSVNLMYGVDKHESKITSTAGGGTLSLEFGVLSRLTNDPVFEQVAKNAVRGLWARRSNLDLVGAHINVFTGEWTQKDAGIGTSIDSFYEYLLKAYILFGDEEYLYIFQEAYRSAMQYLHKDPWYVEVNMDSAAIVWPVFNSLQAFWPGLQVLAGDVDPAIRTHTAFFSVWKRYGFTPEGFNLATLSVQYGQKSYPLRPELIESTYWLYKATRDPRYLDAGRDFVASLQYGAKCPCGYCHITDVELHKQEDHMESFFLAETVKYLWLLFDLAVDSDNLVDNGPYKYIFSTEGHLLPITPQISLAREHCSYFGGYCPSNSTKLEQEVLGEDSSNDDHSNDYPYHESFPVTGLIKGLCPGLTHAQKYGFSYVLPEKTDREDVNQPKPVVTSSSIVLISDQTVEKRPQEEEGFTSQSEPIMTISGGSSNDQTGQELTLLESETDDQRSYSS
What is the function of this protein?
Can convert Man(9)GlcNAc(2) and Man(8)GlcNAc(2) into N-glycans with a terminal alpha-1,6-linked Man residue in the C-branch.  Functions in the formation of unique N-glycan structures that are specifically recognized by components of the endoplasmic reticulum-associated degradation (ERAD) machinery, which leads to the degradation of misfolded glycoproteins.  Most likely generates N-glycan signal on misfolded glycoproteins that is subsequently recognized by OS9.  Required for ERAD of the heavily glycosylated and misfolded BRI1 variants BRI1-5 and BRI1-9.  Does not seem to play role in N-glycan processing of correctly folded proteins destined for secretion.
What are the official names of this protein?
Alpha-mannosidase I MNS4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: VKTF1_CYRHA
Sequence: MGTARFLRAVLLLSVLLMVTFPALLSAEHHDGRVGICRLPSDSGDCLRFFEMWYFDGTTCTKFVYGGYGGNNNRFPTEKACMKRCAKA
What is the function of this protein?
Serine protease inhibitor that inhibits chymotrypsin and blocks voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type U15-theraphotoxin-Hhn1f, U15-TRTX-Hhn1f, Kunitz-type serine protease inhibitor hainantoxin-XI-6, HNTX-XI-6.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 03 (sub-Kunitz) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DSDX_ECOLI
Sequence: MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSVDVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPPHPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKTLPSLGATLFTILLPIALMLVKTIAELNMARESGLYILVEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNAILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII
What is the function of this protein?
A D-serine-specific transporter, may function as a H(+) symporter.
What are the official names of this protein?
D-serine transporter DsdX.
What is the protein family that this protein belongs to?
Belongs to the GntP permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNFE_YERP3
Sequence: MSEAKNLLAQGLWKNNSALVQLLGLCPLLAVSSTATNALGLGLATTLVLVCTNTAVSALRRWVPSEIRIPIYVMIIASVVSTVQMLINAYAFGLYQSLGIFIPLIVTNCIVIGRAEAYAAKNPVGLSALDGFAMGMGATCALFVLGALREILGNGTLFDGADMLLGSWATVLRIDILHLDTPFLLAMLPPGAFIGLGLLLAGKYVIDEKMKARKANTRVSVPQLQDGDAEKAL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR19_SPIMX
Sequence: MTRSLKKGPNVADHLLKKIENLNSQGEKRVIVTWSRGSTIVPAMIGHTIAVYNGREHLPIFVTDLMVGHKLGEFSPTRTFRGHAKSDKKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FER2_PEA
Sequence: ATYNIKLITPEGTKEITCSDSEYILDAAEEKGLDLPYSCR
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin-2, Ferredoxin II.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSMA_STRP4
Sequence: MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEIDDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDILKVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRISAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVEDENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLAEFAGLADALKGQGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1859_ARCFU
Sequence: MSFSLQLTRLKARLYFPQYHLPPFLGNKFRGGFGSVLLKAVCSYLKPSCNICKSVDDCLYHALYTRDRQKRGRSQPVRPIVFIPPFFGRSVSGRGELTLYINVFGDYVKYLPHIIYGLRYLGKMGLNATSKYEIVSISDAISGKEVYDGETVFVENLSSIELGKIKPREVEKEIEVDYLTPMEAKTPINLPFLIHIVRRRLILFVNEYGSGEVPEFYCEAETLESSWEKHELHHRSKRQGLRSFFGVTGRARYSISEIDDNALTLLSIGELIGGGAKASFGMGFFRIRS
What are the official names of this protein?
Uncharacterized protein AF_1859.
Protein: MLTF_CITK8
Sequence: MKKLKINYLFIGILTLLLAAALWPSIPWFGKADNRIAAIQSRGELRVSTIESPLTYARINGKKYGLDYELAQQFASYLGVKLKITVRQNISQLFDDLDNGNADLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYRVGQYRPRTLATVNESQLSIAPGHVVVNDLQALKETKFPDLSWKVDDKKGTAALLSEVISGNLDYTIADSVAISLFQRVHPELAVALDVTDEQPVTWFSQLDDDNTLSAALLDFFNTINEDGSLARMEEKYLGHGDDFDYVDTRTFLRAVDGVLPDLQPLFEKYAQEIDWRLLAAISYQESHWDPLATSPTGVRGLMMLTKNTAQSLGLTDRTDAEQSISGGVRYIQDMMGKVPETVPEEERIWFALAAYNMGYAHMLDARALTVKTRGNPDSWADVKQRLPLLSQKQYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQAAEAIKLAQDYPAVSPAEFDTETFPFSSFLSQPSSNYLSHSPSLPFSLKKKDEN
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: DBP8_CANGA
Sequence: MTEEVSRKQNFRQLGLSKWLVESLDAMRIRTPTAIQSGCIPEILKGRDCIGGAKTGSGKTIAFAGPMLTQWSEDPTGMFGIVLTPTRELAMQIAEQFTALGSYMNIRVALVVGGESIVDQALQLQRKPHFIIATPGRLAHHILNSGDDTVGGLKRVKYLVLDEADILLTETFSNDLKTCVGALPPKEKRQTLLFTATITDQVRALQDAPVQKGKQPLFCYEVENVDNVAIPSTLNTEYVLVPEHVKEAYLYQLLTCESYANSTAIIFVNRTTAAEVLRRTLKALDVRVASLHSQMPQQERTNSMHRFRANAARVLIATDVASRGLDIPTVELVINYDIPSDPDTFIHRSGRTARAGRKGDAISFITQRDVSRIEAIEARINMKMTECDKVHDTAVIRKALTKVSKAKREALMAMEKENFGERRKLQKRKTQKDGKRV
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ACPS_CHLAB
Sequence: MQIAHIGTDIIEISRIRKAIKTHNQRMLNKIFTKKEQVYCLRLIDPCPSLAARFAGKEAVAKALGTGIGKIVGWKDIEILKISKQPEVFLPERVYQKLGISKVLLSISHSREYATAMAIALI
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_CHRSD
Sequence: MSWWTPQVAAIAFALFQAVVILLAAVGAAALLTMVERRLLGLWQDRHGPNRVGPFGVLQIVADMLKIVFKEDWIPPFADRGLFVLAPAIAMASLLLSFMVIPITPSWGVADLHIGLLFFFAMAGINVYAVLFAGWSSGNKYALLGAMRASAQTLSYEVFMGLSLMGVVAMAGSFNMREIVAAQETLWFIVPQFFGFCTFLVAGIAVTHRHPFDQPEAEQELADGYHIEYSGMKWGMFFVGEYVGIVLVSALMVTLFLGGWHGPWLPPIVWFLLKTAVFVGFFILLRAALPRPRYDAVMSFGWKVCLPLTLINLLVTGALILIFSPAGG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VP1_POVK6
Sequence: MSCTPCRPQKRLTRPRSQVPRVQTLATEVKKGGVEVLAAVPLSEETEFKVELFVKPVIGNTTAAQDGREPTPHYWSISSAIHDKESGSSIKVEETPDADTTVCYSLAEIAPPDIPNQVSECDMKVWELYRMETELLVVPLVNALGNTNGVVHGLAGTQLYFWAVGGQPLDVVGVTPTDKYKGPTTYTINPPGDPRTLHVYNSNTPKAKVTSERYSVESWAPDPSRNDNCRYFGRVVGGAATPPVVSYGNNSTIPLLDENGIGILCLQGRLYITCADMLGTANSRIHTPMARFFRLHFRQRRVKNPFTMNVLYKQVFNRPTETVDAQVGVTEVTMVEEIGPLPPSIQTTLPTSVNLTQLPRTVTLQSQAPLLNTQQNSK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins.  Interacts with sialic acids on the cell surface to provide virion attachment to target cell.  Once attached, the virion is internalized by endocytosis and traffics to the endoplasmic reticulum.  Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.  Next, the virion uses the endoplasmic reticulum-associated degradation machinery to probably translocate in the cytosol before reaching the nucleus.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2/Vp3 nuclear localization signal.  In late phase of infection, neo-synthesized VP1 encapsulates replicated genomic DNA in the nucleus, and participates in rearranging nucleosomes around the viral DNA.
What are the official names of this protein?
Major capsid protein VP1, Major structural protein VP1.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses coat protein VP1 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: KDUI_ECO45
Sequence: MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDRIIVGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: SYDN_CAEEL
Sequence: MGEPSPSRRRSITSGIPCPSPTKQVLPPPPPEELHNILRKRPRSSAIPTTSQTHVRAPRKETDVVDRIWHDIDEEQREKLARRKEEAAKRKEQQPAQHIRDYLPLTATNLRNFRNEDSTISDFIHRQGMVDKLLGYKMLLGKMENCGTLGYEKMSEDEVQQLSREWLKNFFPSEQAHVGPRTPPSPAVDSDGGSYPKRPRRGPKTPPGSPGPSMDQAAVNRRELIEQLARNFGISSYKVEETLGTGLDKALEDCSKKLKNELMETFKDQLLSQIDRKTKIRDDLSDQMELVSDCSLSPDLIKKEEPDVVYHMAVPPPPIPPPIQPPPYSYYPVAPAAAPQVYHYAPPPPPPPPHPQQGLYQQNMMAYPPPMQHFNAPPPPMAPYQHQAPPSIVLPPVNVPPPPIGVRIDTPIPTAVLPIPTMVPPPPLPPPQAPFSGDCWRAQPAAPVPASVPVSSAPPPSVVVNVQSTLFSALGLHHKPPPPPPPPPPPTTSSTTTSHIPPPPPPPLPFSSAPPPPPPLPMVAAGPSPPSFVPPPPPPNPNQNPSIVLSPSAVTGGGGYRHRVNQFPPQQQQSFSNF
What is the function of this protein?
Acts as a negative regulator of nuclear pre-mRNA 3'-end processing (mRNA polyadenylation) (Probable) (PubMed:26588990).  Plays a role in tissue-specific expression of protein isoforms by regulating differential processing of pre-mRNA 3'-end (alternative polyadenylation) (PubMed:26588990, PubMed:28087624).  In neurons, regulates alternative polyadenylation of specific mRNAs including unc-44 and dlk-1 by interacting with phosphatase ssup-72 and thus preventing ssup-72 dephosphorylation of RNA polymerase II subunit ama-1 (PubMed:26588990).  Specifically, alters the usage of internal polyadenylation sites (PAS) to promote the production of neuron-specific unc-44 isoform and dlk-1 isoform c, both required for normal synapse and axon development (PubMed:26588990).  Conversely, in the epidermis, by inhibiting ssup-72 function, promotes the usage of an internal PAS preventing the production of one of unc-44 isoforms (PubMed:28087624).  In neurons, also negatively regulates protein levels of pre-RNA processing protein psf-2 (PubMed:20530551).
What are the official names of this protein?
Synaptic defective enhancer 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Also localizes to a small subnuclear ring in neurons. In neurons, partially co-localizes with pfs-2 in the nucleus.
Protein: G6PI_SYNP6
Sequence: MTAQQLWQRYLDWLYYDPSLEFYLDISRMGFDDAFVTSMQPKFQHAFAAMAELEAGAIANPDEQRMVGHYWLRDPELAPTPELQTQIRDTLAAIQDFALKVHSGVLRPPTGSRFTDILSIGIGGSALGPQFVSEALRPQAALLQIHFFDNTDPAGFDRVLADLGDRLASTLVIVISKSGGTPETRNGMLEVQSAFAQRGIAFAPQAVAVTGVGSHLDHVAITERWLARFPMEDWVGGRTSELSAVGLLSAALLGIDITAMLAGARQMDALTRHSDLRQNPAALLALSWYWAGNGQGKKDMVILPYKDSLLLFSRYLQQLIMESLGKERDLLGKVVHQGIAVYGNKGSTDQHAYVQQLREGIPNFFATFIEVLEDRQGPSPVVEPGITSGDYLSGLLQGTRAALYENGRESITITVPRVDAQQVGALIALYERAVGLYASLVGINAYHQPGVEAGKKAAAGVLEIQRQIVELLQQGQPLSIAAIADDLGQSEQIETIYKILRHLEANQRGVQLTGDRHNPLSLIASWQR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXJ1_HETVE
Sequence: DDCGTLFSGCDTSKDCCEGYVCHLWCKYK
What is the function of this protein?
Inhibitor of voltage-gated potassium channels of the Kv4/KCND family (By similarity).  Blocks calcium channels (Cav).
What are the official names of this protein?
Kappa-sparatoxin-Hv1e, Kappa-SPRTX-Hv1e, Toxin KJ1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 19 (HpTX2) subfamily.
What are the subcellular locations of this protein?
Secreted.