PharMolix/UniProtQA huggingface dataset:
Protein: GATA_PELPD
Sequence: MDLFDLTLHELHAKLKSKEVSSREATSAMLDRIAELEPRINAFITVTPERALAEAEAADRRIAAGEADVLTGIPLAVKDIFLTEGTLTTCGSRILNNFIPPYSATSFEKLKQRGMVLLGKLNQDEFAMGSSNESSASGPCRNPWNTDCIPGGSSGGSAAAIAARQATVTLGTDTGGSIRQPASHCGCVGLKPTYGRVSRYGVIAYASSLDQVGPLTRDVTDCAIMLGALAGHDPKDSTSVDRPVPDYQAALTNDIRGLRIGLPREYFIEGLDPDVQASMDQAIETYRRLGAEFTEISLPHTDYAVASYYLIATAEASANLARYDGVRFGHRAEQAEGLLEMYSRSRSQGFGSEVKRRIMLGTYALSSGYYDAYYLKAQKVRTLIMADFIQAFEGVDLILTPVAPTPAFRIGEKVNDPLQMYLSDIFTIPVNLAGTCAMSLPAGISGQGLPIGVQLIGKPFGEETILRAAHAFEQATEWHSLRAPL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RL17_SYNS3
Sequence: MRHQCRVPLLGRPADQRKALLRGLTTQLIREGRVTTTKARAKALRDEAERMITLAKNGSLASRRRVLGYVYDKQLVHALFDKAPTRYGDRNGGYTRITRTVPRRGDNAEMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL7_MYCAP
Sequence: MAKLTKESFISSLKEMSIKEVMELVEAMKEEFGIDPSAVAVAAAAPAAEAEEKKSTLSVILKSDNGKKLAIVKAVKELLNLALMDANKLVSTLPATLKENIPAAEAEALKAKLVEAGADVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: IDI2_METMA
Sequence: MINTTSRRKIEHLKLCAESPVEARQVSAGFEDVTLIHRALPELNMDELDLSVDFLGKRIKAPFLIASITGGHPDTIPVNAALAAAAEELGVGIGVGSQRAAIDDPSQEDSFRVVRDEAPDAFVYGNVGAAQIRQYGVEGVEKLIEMIDADALAIHLNFLQEAVQPEGDRDATGCLDMITEICSQIKTPVIVKETGAGISREDAILFQKAGVSAIDVGGAGGTSWAGVEVYRAKESRDSVSERLGELFWDFGIPTVASLIESRVSLPLIATGGIRNGLDIAKSIALGASAASAALPFVGPSLEGKESVVRVLSCMLEEFKAAMFLCGCGNIKDLHNSPVVVTGWTREYLEQRGFNVKDLSLPGNAL
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HELX_METTH
Sequence: MIKKQERMYTSGEIHSILHPWVSEWFRRTFDDFTEAQRYAIMDIHRGRNVLVSSPTGSGKTLTAFLSIISELTRLADDGELEDSVYCIYISPLKALDNDIERNLEEPLSAIRDIAAGEGRDLEIRKAVRTGDTTSYERSRMLKKPPHILITTPETLSILLVAPKFREKLSTVRYVIVDEIHSLADNKRGVHLSLSLERLQHLVGDFTRIGLSATVHPLERVARFLVGYSYGSERECLIVDVSYLKELDIDLICPVDDIVAADPEEIGNALYDILHDLIEDHRTTLIFTNTRSGTESVVYNLKSRFPESYSDSNIMAHHSSLSREIRLETEEKLKRGELKAVVSSTSLELGIDIGYIDLVVLLSSPKSVSRALQRIGRSGHQLHQRSKGRIVVVDRDDLVECSLILKNALEGKIDSIKVPENCLDVLAQHIYGMAIENPWDIDHALAVIRNSYCYRNLSREDYLSVLSYLAGEYVELEERYVYAKIWVDYDKNQFGKRGKLARMLYSTNIGTIPDRSAAVVKCGGKVVGRIEEDFMEKLRKGDTFVLGGRIYRFNYARGMTVNVTPASGPPTIPSWFSEQLPLSFDLALDIQRFRDIMDGKFQYGRSRDEIMEFIMSYLHVDERAASSIYEYFREQYLYAGIPSIRRMLVEYYTGFGGRKFIVFHSLFGRRVNDAISRAVAYVIARRYRRDVMISVSDNGFYLSSEGKMGGLEAFRELEPENLRNVLKKALDRTETLASRFRHCAGRALMILRRYRGEEKSVGRQQVRGKILLKFVSELDDKFPILEEARREVMEDYMDIENAIRVLEWIRDGDMEIKQINTRIPSPFAFNLVAQGYLDVLKYEDRIEFIRRMHQAIIDEIKR
What are the official names of this protein?
Uncharacterized ATP-dependent helicase MTH_1802.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
Protein: EFTS_SYNC1
Sequence: MKITASMVSELRTKTGAGMMDCKKALSEADGNIEEAVDILRKKGLSAAAKKADRAAAEGLVVGLNEGSCGVLVEVNAETDFVAKNANFQEFTNGVAKVVVSSKPADLEALKALPFPGTDRTVAEEQTHQIATIGENINLRRFVCFDVAQGAVAVYIHGVGKIGVLVELETSKGDDERVAALGRNLAMHIAAANPQYLNRDEVSAEVVEKEKEIMRTKALESGKPEKIVEKIIAGQINKYFGEVCLLEQAYVIDPDLTVTKVVENLGKEIGAEVTLSRYVRFQLGEGLEKRSDDFAAEVASMTK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTC_CAUVN
Sequence: MSAHRVLLEVCVDTPAGLAAAIAGGADRVELCSALALQGLTPAPGLMAQAASAPIPVYPMIRPRHGDFCYDARDLDAMRRDIDAVRGYGLPGVTIGASQANGALDLKVLRKLVEQAEGLGTTLHRAFDVVPDMSEALEIAVELGFERVLTSGGALSALDATDRLAALVEQAGERISIMAGAGVRPGNIAELVRRTGVREAHGSFGGPVPGADPRSQLGAMGFVPPELRDTSQAAVAEAVKALRAL
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK_ESCF3
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEVLDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGSAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAKGRDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASIACITEREREIALKAARTMALDVAGVDILRAERGPLVMEVNASPGLEGIEKTTGVDIAGKMIRWIERHATPEFCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: VA0D1_PONAB
Sequence: MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLTVSVIDDRLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTLYKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  May play a role in coupling of proton transport and ATP hydrolysis (By similarity).  In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity).  May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit d 1, V-ATPase subunit d 1, Vacuolar proton pump subunit d 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: CHED_DESHD
Sequence: MSNVISVGMADLKTTKAPNILMTAGLGSCIGICVHDPIQKVGGMAHIMLPTAGSAPGGNPAKYADTAMDLLVTEILRLGASKSRLRAKMAGGAQMFSFPGKPPVLKIGDRNAEQVIVELKRLGIPLLVSDVGGSFGRTIHFDVGTGDLKVRTINHGEKVI
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: LRK22_ARATH
Sequence: MAGVLRSLRFWMIICVQVLSLVLAQDRDEFVYHDFSQADLHLDGMASIDDGRLHLTNNTTKSTGHAFWKIPMNFTTSPSSSLSFSTEFVFAIFPLLGDGQGMAFVVAPFMDIRYSGDAASYLGLFNRKNDNKTENHILAVELDTNSSPEAIEDSDNHVGIDINSIISEDSANASYFSGTEGKNISFRLASEKSILVWIDYNGTEKLLNVTVAPVPTPKPALPYLSSSIKPRKPLLSRFINISEIFNGTMFVGFSGSTGTVKSDQYILGWSFKKGGQAESLDLSKILDPPNRPPPPSSPPPPPPPPPTPPTSRSKDSKNIIIICVTVTSIAFLLMLGGFLYLYKKKKYAEVLEHWENEYSPQRYSFRNLYKAIRGFRENRLLGAGGFGKVYKGELPSGTQIAVKRVYHNAEQGMKQYAAEIASMGRLRHKNLVQLLGYCRRKGELLLVYDYMPNGSLDDYLFNKNKLKDLTWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGRLGDFGLARFHDRGENLQATRVVGTIGYMAPELTAMGVATTKTDIYAFGSFILEVVCGRRPVEPDRPPEQMHLLKWVATCGKRDTLMDVVDSKLGDFKAKEAKLLLKLGMLCSQSNPESRPSMRHIIQYLEGNATIPSISFDTAGFGIPNISNETITQMTATSSSANFSFEDVTILFGGR
What are the official names of this protein?
Putative L-type lectin-domain containing receptor kinase II.2, LecRK-II.2.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SYY_CLOBB
Sequence: MANVLDELLDRGYIKQFTHEEETRKLLENEKVTFYIGFDPTADSLHVGHFIAMMFMAHMQRAGHRPIALLGGGTAMVGDPSGKTDMRKMLTKEQIQHNVDSIKKQMERFIDFSDDKALIVNNADWLLDLNYVDFLREVGVHFSVNRMLSAECFKQRLEKGLSFLEFNYMLMQGYDFYVLNQKYGCKMELGGDDQWSNMIAGVELVRRKAQGDAMAMTCTLLTNSQGQKMGKTVGGALWLDADKVSPFDFYQYWRNVDDADVEKCLALLTFLPMDEVRRLGALEGAEINGAKKILAYEVTKLVHGDEEAKKAEEAANALFSGGADMSNVPTVIISKEDLGSTVLDVIAKVKIVPSKKEGRRLIEQGGLSINGEKITELTRTLNDDDFKDGSALIKRGKKNYNKIEIQ
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_FRAP2
Sequence: MARVTVEDCLDKVETRFDLVVLASMRANNILKKGYSESADNEKKEKATVVALREIAESEITPDQILRNEIEG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: LFTR_DESVH
Sequence: MRLYLLPDDACIFPDVGEAGPDGLLAIGGDLTPERLLRAYEEGIFPWYGPGDPILWWSPDPRCVLPLDALHVPRRLMRTVRAKTFEVRLDTAFADVLEQCAATPRPGQGGTWLVPEMRAAYTRLHHLGHAHSVEAWYGGRLVGGLYGVALGGGFFGESMFHAMPDASKVAFVWLARLLVSWGFRFVDCQQTTSHMLRFGAVEMPRTDFLACLHDATRQPSRIGRWRLPQDFVPW
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPCF_SYNY3
Sequence: MEGNSVVTPEIERLIQAVETADSAAKLVGAVRALAATRSPLAVPQLTTVLRYNNPGAAVAAVDGLIQIGDAAMTHLLANMDGYNYGARAWATRACAGIGDPRALALLQEAALTDFALSVRRAAAKGLGFLRWQSLPQEEQETVQKAIYDTLIQVCEDPEWVVRYGAIAGLENLAKQAQHYRQPLKDFLQSFVEQEPEAIVGERILWTLENIGPI
What is the function of this protein?
Required for the chromophorylation of the cpcA gene product.
What are the official names of this protein?
Phycocyanin alpha phycocyanobilin lyase CpcF.
What is the protein family that this protein belongs to?
Belongs to the CpcE/RpcE/PecE family.
Protein: METK_SYNWW
Sequence: MARTLFTSESVTEGHPDKVADQISDAILDAIMELDPYGRVAAETIVTTGLVLVAGEITTNCYVDIPRLVRSTIEDIGYTRAKYGFDAETCAVLTSLDEQSGDIALGVDRAFEAKKGEMDDKELDAIGAGDQGMMFGYASNETAVLMPMPIYLASKMAERLGEVRKEGIIPYLRPDGKTQVTVEYEDYKPLRVTTVVVSAQHHPEVSSATIEKDIIEHVIKAVIPPEMIDAHTIFYVNPTGRFVIGGPQGDSGLTGRKIIVDTYGGMARHGGGAFSGKDPTKVDRSASYMLRYVAKNIVAAGLAERCEIQVAYAIGVANPLSINVNTFGTGKISDDKIIELIKKNFDLRPAAIIRDLDLRRPIYRKTAAYGHFGREDAEFTWERTDKADTLREQAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDPM_SCHPO
Sequence: MELRVKGRVRHTYIQCSNPIRMTFGHSKEINRRLGTKSENSIPKIQYIYISSFVITNTESYSYPPLLIISESS
What are the official names of this protein?
Uncharacterized protein C29A4.22.
Protein: RS4_GOSHI
Sequence: MARGLKKHLKRLNAPRHWMLDKLGGAFAPKPSSGPHKSRECLPLILILRNRLKYALTYREVIAILMQRHVMVDGKVRTDKTYPAGFMDVVSIPKTNEDFRLLYDTKGRFCLHAITGDETKFKLCKVRSVQFGQKGIPYLNTYDGRTIRYPDPLIKANDTIKLDLESNKIVDFIKFDVGNVVMVTGGRNRGRVGVIKNREKHKGSFETIHVQDAAGHEFATRLGNVFTIGKGTKPWVSLPKRKGIKLSIIEEARKRLAAQNAA
What are the official names of this protein?
40S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_SHIDS
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PLSY_CHLPD
Sequence: MLTLIAILAISYLVGAIPTGIMAGKMLKGIDIRQFGSGNAGGTNAFRVLGWKAGLAVTLLDILKGIVAAVSIVAFFRHHPVGAFPDINEVALRLLAGMSAVIGHVFTVFAGFKGGKGVSTAAGMLIGIAPVSMLIVIGIFLLTVYVSRYVSVASILAAIAFPLIIAIRKYIFELGGGLDYYVKLFGERFSFHDSLDYHLMIFGLIVALAILYTHRANIRRLLSGTENRIKFGRHS
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DBP9_ASPFU
Sequence: MRKTFQPVVSYNQASFKGPSQRLLELCVVNMKRKLDANDVPSTEVEEEKNTKDADNTDFESLNLDPRLRQALIKEQFTKPTPVQSKAIPLALEGKDILARAKTGSGKTAAYVLPILQTILQKKAADPSLKATTGLILVPTRELAEQVQSVIIKFSAFCGKDVRSVNLTQKVSDAVQRTMLADYPDLIVSTPARVIANLGTSALSLENLTHLVIDEADLVLSYGYDEDINALAKAIPRGVQTFLMSATLTSEVDTLKGLFCRSPVILKLEDKEDEGAGISQFVVRCAEDEKFLLTYVIFKLQLIKGKVIIFVGDIDRCYRLKLFLEQFGIKSCVLNSELPINSRIHVVQEFNKGVYDIIIAADEQEVMGLRTSSKKSKEATDGDDEAKDKMGSSEDEDNEPEQSGKSARPEKRRKTSGKAKDYGISRGIDFQNVACVLNFDLPTTSKSYTHRIGRTGRAGKAGMALSFVVPADKFGKHKPTSFPTAKHDESVLAKIVKKQAKLGHEVKPYHFEMKQVDAFRYRMTDALRAVTRLAIQEARAREIRQELVKSEKLKRHFEENPEELKQLRHDGELRAARIQPHLKHIPDYLMPSKGRKGISSEDVGFVGFRKSGDNRIRKAREKNRGKGKGRKPSGVRKVDPLKTFNRGRK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL5_PROA2
Sequence: MTKKDEKGSNLDIPVSRLAESYKEKVVPALMERFQYKNIMMVPKLTKISINIGVGEAASEPKLLETAMQELAQITGQKPQIRKARKAISNFKLREGQPIGCRVTLRKKYMYEFLDRFVTLAVPRIRDFRGLSNTSFDGRGNYTLGIREQIIFPEIDIDKVPRIQGMDISFVTTARTDEEAFALLSELGMPFKKKNN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: P14_ASFK5
Sequence: MADLNSPIQYLKDDFKDQTSIGSLEYDENSDTMIPSFAAGLENYEPIPSPTTSSSLYSHLTHNMEKIAEEDDINFLHDTREFTSLVPDEADNKPEDDEESGGAKPKKKKHLFPKLSSHKSK
What is the function of this protein?
Structural protein required for transport of intracellular particles from the assembly sites to the plasma membrane (By similarity).  Binds to both ssDNA and dsDNA (By similarity).  Suppressed the activation of the cGAS/STING pathway by interfering with the recruitment of IRF3 to TBK1, which in turn suppresses IRF3 phosphorylation, decreasing interferon production (By similarity).
What are the official names of this protein?
Protein p14.5, pE120R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus structural protein p14.5 family.
What are the subcellular locations of this protein?
Virion. Note=Localizes at the surface of the intracellular virion.
Protein: UVRA_RICBR
Sequence: MNQEYIKVRGAKEHNLKNINVDIPRNKFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSSYARQFLHLQNKPNVESISGLSPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLYARVGIPYSPATGLPIHSQTVSEMVDIINELPQGTKIYLLAPIVRGHKGEFKREIMNLKKQGFQKLIVNGETCEIDDLPKLDKNKKHNIEVIVDRIVLDENLGNRLADSLESSLNLADGITYLEIVELPTAANTEYEKNQRITFSEKYSCPVSGFQLTEIEPRIFSFNSPFGACPKCEGIGKEFFFDRDLIVPDHRISIKDGAIVPWGSTSSKFILETLKALAEHYRFSIESPFSALSDNIKTILFEGSGEEAIRFEFHDGSKTQVIHQPFAGIIPSLQEKDRTIESVLIKEELAKFKSEHKCTACNGYRLKDEALCVKIVNIHIGEVADMSIATLQQWFAHLEQKLNKKQLFIAERILKEINERLKFLMNVGLDYLTLSRESGTLSGGESQRIRLASQIGSGLSGVLYVLDEPSIGLHQRDNTRLIETLKRLRDLGNTVLVVEHDEETMYEADHIIDIGPGAGIHGGRVIAEGNAEEIKNFEESITGRYLSGRQTIKVPTQTRTGHDNRAIELIGAVSNNLDNVDIKIPLGTFTAITGVSGSGKSSLMIHTLYKAALKHLEPTAKVFPGKYQKLKGLEYIDKIIDINQSPIGRTPRSNPATYTGAFTHIRDWFVELPESKARGYKVGRFSFNVKGGRCEACQGDGLIKIEMHFLPDVYVKCDICNGHRYNRETLEIKYKGKSIADILMMTVEDAMQFFEKIPLIYEKLITLNEVGLGYIKIGQSATTLSGGEAQRVKLAKELSRRSTGKTLYILDEPTTGLHIDDINKLLKVLHKLVDMGNTVLVIEHNLDVIKTADYIIDVGPEGGDKGGKIVVHGTPADIAACSESHTGRYLKQYLK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_ECO45
Sequence: MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: CCD25_BOVIN
Sequence: MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRLHKGEKIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKMERFPDLEAEKECRDHEERNEKKAQIQEMKRREKEEMKKKREMDELRSYSSLMKVENMSSNQDGNDSDEFM
What is the function of this protein?
Transmembrane receptor that senses neutrophil extracellular traps (NETs) and triggers the ILK-PARVB pathway to enhance cell motility.  NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation.  Formation of NETs is also associated with cancer metastasis, NET-DNA acting as a chemotactic factor to attract cancer cells.  Specifically binds NETs on its extracellular region, in particular the 8-OHdG-enriched DNA present in NETs, and recruits ILK, initiating the ILK-PARVB cascade to induce cytoskeleton rearrangement and directional migration of cells.
What are the official names of this protein?
Coiled-coil domain-containing protein 25.
What is the protein family that this protein belongs to?
Belongs to the CCDC25 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endomembrane system. Note=Localizes to cytoplasmic membrane in tumor cells.
Protein: ITAV_HUMAN
Sequence: MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET
What is the function of this protein?
(Microbial infection) In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
What are the official names of this protein?
Integrin alpha-V, Vitronectin receptor, Vitronectin receptor subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.
Protein: EFCB8_MOUSE
Sequence: MPSSLHAPLSGEVSAFSLSCPYFRCQDSTGEDLGRFPSPLPFLMCLLLFFPFRARWPRLMSSEKPGESPKPQKMAQPGGSQKKETSRSVPVTDPTSHNSEINQRDQQFSDMHLADLQKVFEKEADENGALKKEGFIRIMKGVLSSMSEEMLELLFLKVDSDCNGFVTWQKYVDYMMREFQGKEEMRKSQYRLRFHLPMTVIPL
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 8.
Protein: CREN7_SULTO
Sequence: MIGMAEKKVKVKTPSGKEAELAPEKVWVLAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPV
What is the function of this protein?
A probable chromatin protein, binds double-strand DNA without sequence specificity.  Constrains negative DNA supercoils.
What are the official names of this protein?
Chromatin protein Cren7.
What is the protein family that this protein belongs to?
Belongs to the Cren7 family.
What are the subcellular locations of this protein?
Cytoplasm.