PharMolix/UniProtQA huggingface dataset:
Protein: RBFA_CHLTB
Sequence: MAENRRMKKVNAMLREAIAKVILKDVKHPKISNRWITITRVSLSRDLQSACVYVSIMPHENSQEETLAALKASAGFIAFQASKDLVLKYFPDLNFYVEDIFSPQDHIESLLLKIAEQDKKTNP
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARMX3_RAT
Sequence: MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGPGDVEDAGDCSGARYNDWSDDDDDSNESKSIVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKIYMNQVCDDTVTSRLNSSVQLAGLRLLTNMTVTNEYQHILANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLGAHVPSSLGSLFNKKEYKEVILKLLSIFENINDNFKWEENEPAQNHFSEGSLFFFLKEFQVCADKVLGIESHHDFQVRVKVGKFVTKLTERMFPKSQE
What is the function of this protein?
Regulates mitochondrial aggregation and transport in axons in living neurons.  May link mitochondria to the Trak2-kinesin motor complex via its interaction with Miro and Trak2.  Mitochondrial distribution and dynamics is regulated through Armcx3 protein degradation, which is promoted by PCK and negatively regulated by Wnt1.  Enhances the Sox10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters.
What are the official names of this protein?
Armadillo repeat-containing X-linked protein 3.
What is the protein family that this protein belongs to?
Belongs to the eutherian X-chromosome-specific Armcx family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus.
Protein: BACB_BACLI
Sequence: MSMSIMDFINDLKKKNITLYHNKGKIKIIGPQELLTADLKQQIKRYKEDIIAALEAGETDIERSFPKAAPSKSGTYPLSREQKRMFILNQLDDSKTAYNMPLAVKINGEVQISRLEQAWKALIKRHESLRTSFVMLDGEPVQKIEQEAEFRLEYSELGDQSIQEKISRFIKPFELEKAPLLRAEIVKVDEAEHMMMVDMHHIISDGVSIGILMKEFADCCEGKELSPLAVQYKDYSEWQRDIEQQSRLKKQEAYWLNTFRGDIPVLNMPLDFPRPKIRSFQGNRTVVELDQDTTKKLKTIAAKNGVTMYMLLLAGYTILLSKYTGQEDIIVGSPIAGRPHADLNGTIGMFVGTLALRNRPKGNMTFSEYVQTVKNNTLKAYENQDYQFDALIEHLGLTHDMSRNPLFDTMFDLQHADDFASEAGGGHFETYDIPFHVAKFDVSLTAFLHGDNLKFDFQYCTDLYKKETVERMAGHFLNVLKDAAHHPELALSEIRMMSEEEKDIILHTFNHEKTDGPKNKTLSRLFEERAEKTPDHTAVIFEDQQLTYRELNEKANQLAWLLREKGVKPDTIVAIMTDRSLEMIIGIIGILKAGGAYLPIDPDYPEDRVKYMLEDSGADMVVIQEPFKSKIDGRQLITAEDTRSFSKENLPNVNKASDLAYVIYTSGSSGRPKGVMTTHRNVVHYVDAFTKRIPLSEHDTVLQVVSFSFDAFSEEVYPILACSGRLVISRKVSDLNIDELVKTIGKYRVTLVSCSPLLLNEIDKNQHLTFHPQMKFISGGDVLKFEYVENIIKGADVYNSYGPTEATVCATYYQLSSADRKKTSIPIGKPLSNYKVYIADQYGRPQPVGVPGELLIGGEGVARGYLNHETLTKAAFVVDESGERVYRTGDLARWLSDGNIEFLGRIDSQVKIRGYRIELEEIEHRLLMNDNINEAIVVAKEDQENSKYLCAYIAFNNKNADIEQVQERLAKDLPEYMIPSCFIKLDQIPRTINGKADLKALPEPDRRAFAQARYEAPRNQTEALLLSIWQDILPAEQIGINDHFFDIGGHSLKAFSMAAKIQSALKVEVTLKEIFNHSTIQDLAAYIAQKQKQVQSDIQKAEKKEYYPLSSAQKRLYILNQIEEGQTAYNMPFAMKIKGELQTDKAEKAFRTLIKRHESSRTSFVTINGEPVQNINEEVTFEMKYRELDNCSLRERMNQFIRPFELEKAPLLRAELVRVNAAEHILLLDMHHIISDGVSIGILMKEWAALYEEKELAPLKIQYKDYSEWQRDPWQKDRLKKQEESWLSVFQNDIPVLNMPTDFPRPQMQSYEGDRIAFAIERELTDKLKKTAKENGVTMYMLLLAGYTILLSKYTGQEDIIVGSPIAGRTREELEQTVGMFVGTLAMRNHPKGGRTFIEYLQDVKENTFNAYENQDYPFDELVDKLDLERDISRNALFDTMFDMQALDDAEPDIEGLHVEPVDLEFQISKFDLSLTAAESAGVITFHLEFCTRLYKKETAETLAQHFVNILRDISDHPQKTLNDISMLSEEERHTVLYQFNDTNTEHPSGIFSELFEEQAEKSPNHPAAVFKDQMLTYRELNEKANQLARTLRQKGVQRESVVGIMAERSLEMLTGILAVLKAGGAYMPIDPGLPKERIQYLITDSGADLLLTQHQLIGSISFAGEIIQIDQADAYDTDGSNLEHLNSPGDLAYVIYTSGTTGNPKGVMVEHRNIIHAHYTWRKHYELASFSVNLLQLASMSFDVFAGDLCRSLLNGGTMYIVPDDVKLEMNLLYDMINKYGIHMLESTPSLIIPLMKYIDHHKLDFSSMKLLIMGSDTCTIKDYKWLVERFGQRMRIINSYGVTEASVDSGYYEEALDRIPEIANTPIGKPLDNTAFYILDPSLNPQPVGVYGELYIGGEGIARGYLNKPELTKERFVPNRFAAGGNMYKTGDLARWLPDGNVEFLGRIDHQVKIRGFRIETGEIETKLLENQNISEAVVIDREDKKGHKYLCAYIVARAKTNTNELREYLSDHLPDYMLPSYFIQINKMPLTPNGKIDRKALPEPAGDVIAASGYEAPRNETEEKLAAVWQEVLDRDKIGINDNFFEIGGDSIKALQIVSKLSRADLKLQVKDLFTNPFIRHLSKYVKKETKARTSEIVQGQVPLTPVQRSFFEANQREQNHYNQAFMLYRENGFAERIVEKVFRKLTEHHDALRMVYWEKNGDIIQHNRGLEDSVFDLYVYDLKTEKNLEKTVYQIATNIQKDISISEGKMIKLCVFKTTEGDHLLIAIHHLLVDGVSWRILFEDFEAAYGQALQGKPIELGYKTDSYKTFSEKLAEYANSKKLLKEQEYWREISKGKMAFLPKHRQAAHDNYENSRTLRISLSQTETEQLLKEAHKAYNTQINDLLLTALLIASRQLTGENRLKILMEGHGRDDILQDVDITRTVGWFTAMYPVFIDLEDEADLSVMIKIVKETLRKIPNNGIGYGILKYLRKDEGLLKDEKPPILFNYLGELDHDLTTEQFSSSKLSAGQSIGEKSARDASVEIDSVVAGRQLMISTTFNEYEYSPDTISELNQAFKESLQMVISHCTGKHETEKTSSDYGYDKLSLEDLEELLNEYESVDS
What is the function of this protein?
Activates two amino acids and incorporate a D-ornithine from its second active site into bacitracin.
What are the official names of this protein?
Bacitracin synthase 2, BA2.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: YCGL_ECOLC
Sequence: MPKPGILKSKSMFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMILPLDGRKKLVNADIEKVKLALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK
What are the official names of this protein?
Protein YcgL.
Protein: CFBM1_XENBM
Sequence: GLGSVLGKILKMGANLLGGAPKGA
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Caerulein precursor fragment BM1, CPF-BM1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL4_MACFA
Sequence: MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHSIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQRALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRWNTILRQARNHKLRVDKAAAAAAALEAKSDEKAAVAGKKPVVGKKGKKVAVGVKKQKKPLVGKKAAATKKPAPEKKSTEKKPTTEEKKPAA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICAM3_BOVIN
Sequence: MIASGPPPRVYWTSLIFLLLACCLLPTGAQGQTYQVRVEPKDPVVPFGEPLVVNCTLDCPGPGLISLETALSKEPHSRGLGWAAFRLTNVTGDMEILCSGICNKSQVVGFSNITVFGFPKRVELAPLPLWQPVGEELNLSCLVSGGAPRAHLSVVLLRGEEELGRQPLGKEEPAKVTFMVQPRREDHGTNFSCRSELDLRSQGLELFQNTSAPRKLQTYAMPKTAPRLVFPRFWEMETSWPVNCSLNGLFPASEAHIQLALGNQMLNATVVSHADTLTATATAKTEQEGTQEIVCNVTLGVENRETRESLVAYRFQGPNLNLSESNATEGTPVTVTCAAGPQVQVMLDGVPAAVPGQPAQLQLKATEMDDRRTFFCNATLKVHGVTLHRNRSIQLRVLYGPTIDRAKCPQRLMWKEKTMHILQCQARGNPNPQLQCLREGSKFKVPVGIPFLVLLNYSGTYSCQAASSRGTDKMLVMMDVQGRNPVTINIVLGVLAILGLVTLAAASVYVFWVQRQHDIYHLTPRSTRWRLTSTQPVTVAEELS
What is the function of this protein?
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).  ICAM3 is also a ligand for integrin alpha-D/beta-2.  In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages.
What are the official names of this protein?
Intercellular adhesion molecule 3, ICAM-3.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. ICAM family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PUR7_BACHK
Sequence: MQKLELLYEGKAKRIYRTESADMVWVEYKDSATAFNGEKKETITGKGRLNNEITTLLFRKLQEVGIKTHFVEKLSETEQLVKKVSIIPLEVVTRNVLAGSLSKRLGMEEGTVLAEPIVEFYFKDDDLGDPLVTEDHIRVLNVASPEQVSVLRDMALQINQVLIDHFASCRVRLVDFKLEFGVTDEGAIILADEISPDTCRLWDETSNEKFDKDVFRRDLGNLTDAYEEILKRLGGISHV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: G1PDH_METBU
Sequence: MDVTHDMNGQKKWMQLPRNVVIGNGVINEVRDVCTDLKLIDNALVVTGKSTKGIAGEIVQDSLQDAGQNVELVISESASMKEVERIRKHAIESGTKYFLGVGSGKTIDVAKLAATDLEVPFISVPTAASHDGIVSSRASIKDGKTTTSVQANAPMAVIADTEIIANAPYRLLAAGCGDIISNCTAVLDWQLASRLQNVQFSEYAAALASMTAQILIDSADSIKPELESSVRMVVKALVSSGVAMSIAGSSRPASGSEHMFSHALDRVADEPALHGEQCGVGTILMMYLHGGDWKKISDALKLIGAPTTAKELGIEDKYILEALVLSHTIRPERYTILGTGLTPDAAEIVARKTKVIS
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_DESDA
Sequence: MSEEKIKVSELAKEFPAVPNKDMLRALRELGASAKSMAGSLTTEEAARVREHFAEQKQADAERSGSHPNVIVRRRRKDADKADAPEVTEAAPAAREEVAPPAEEKPAAVEAPAQAEPVAEAPAASPHKVEEKAAPEAAKAEPAEKAKSSKARVVSAARVISRPGEEEEKKPEPVVESKPEPVAEISPVAAALAAREAAARAEEKSSEKGEEKGAKAARLARPDASAMPEGSSAPTLPQRAPEARTEAWKDADASAAADAAPRRAPRADGGQAPSAAPQVRIISRPAPGSQPDRSTRPAGGRPGAPGGPRGDSAGRPPRPGGPRPSGPGGPRPAGGPRPGGFGQQPAAPASPTDTRDGQSKKKRLKGRRTVDFQQGDFGGRRDDDDSQRLNRGKGRRKGGKPTSSQATQPLKAAKRKIRVTEAIRVADMAHQMGLKANEIIKVLFGLGVMATINQALDFDTATLVASEFGYEVEKAGFSEDDYLTPKEVDAPETLKPRPPVVTIMGHVDHGKTSLLDAIRKSNVTSGEAGGITQHIGAYHVKTKRGEIVFLDTPGHEAFTAMRARGAQVTDLVILVVAADDGVMEQTREAINHARAAGVPIMVAVNKMDKPSADPDRVLRELAELGLQAEEWGGDTIVAKVAAKTRMGLDDLLEMVALQSEIMELKANPDKAAKGHIVEAKLDKGRGPVATVLIQEGTLRQGDSFVCGPFSGRVRALMNDQGKKVKEAGPSLPVEVQGFEGVPEAGEEFFVVSDEKLARRIADSRAIKQRERELASESRVTLETFLSQRKSDQETLTLNLVLKSDVQGSLEAITEALLKQSTDKVRINVVHGGTGAITESDILLASASQAIIIGFNVRPTAKIKDVAEHENVDIRFYEIIYKLVDDIKSAMAGLLAPVQREVYLGQAEVRDTFSVPKIGLIAGSYVADGKIARNAGVRLLRDGVVVYTGKISSLKRFKDDAREVVKGNECGVGLENFNDVKIGDIIEAFETVEEAATL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMP13_HORSE
Sequence: MHPGVLAAFLFLSWTRCWSLPVPNDDDDDDDMSEEDFQLAERYLKSYYYPLNPAGILKKTAANSVVDRLREMQSFFGLEVTGKLDDNTLDIMKKPRCGVPDVGEYNVFPRTLKWPKMNLTYRIVNYTPDLTHSEVEKAFKKAFKVWSDVTPLNFTRLYNGTADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFVLPDDDVQGIQYLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGETMVFKDRFFWRLHPQLVDAELFLTKSFWPELPNRIDAAYEHPSKDLIFIFRGRKFWALNGYDILEGYPQKISELGFPKDVKKISAAVHFEDTGKTLFFSGNQVWRYDDTNRMMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPTNSLLWC
What is the function of this protein?
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN.  Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen.  Can also degrade collagen type IV, type XIV and type X.  May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2.  Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification.  Required for normal embryonic bone development and ossification.  Plays a role in the healing of bone fractures via endochondral ossification.  Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2.  Plays a role in keratinocyte migration during wound healing.  May play a role in cell migration and in tumor cell invasion (By similarity).
What are the official names of this protein?
Collagenase 3, Matrix metalloproteinase-13, MMP-13.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: ENGB_WOLTR
Sequence: MVRRITLNSNFMFGASDIKSLPNESAPEIAFAGRSNVGKSSLINLLINSKKAARVSSKPGCTRQINFYSMYNDKFRLVDLPGYGCSHASKDETIQYLGLVEYYLIHRRNLRRVFVLIDSKVRLKEIDKDFIYWLTYNNINFDVVLTKIDKVDRENLDAIIESTRKWINNESVSIRQISVRVKYEMTKVRDEFFKFTR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CART_BOVIN
Sequence: MESPRLRLLPLLGAALLLLLPLLGALAQEDAELQPRALDIYSAVEDASHEKELIEALQEVLKKLKSKRIPIYEKKYGQVPMCDAGEQCAVRKGARIGKLCDCPRGTSCNSFLLKCL
What is the function of this protein?
Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus.
What are the official names of this protein?
Cocaine- and amphetamine-regulated transcript protein.
What is the protein family that this protein belongs to?
Belongs to the CART family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASSY_STAEQ
Sequence: MKDKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDVVYQKALDMGAVECHIIDATKEFSDDYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSIGIAHGCTGKGNDQVRFEVAIKALNPKLKAFAPVREWAWSREEEIDYAIKHNIPVSINYDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTTPLEETPDNADEIILTFKQGIPVQVDGKDYQLDDLILYLNQLAGKHGIGRIDHVENRMVGIKSREIYETPGAEVILKAHKALETITLTKDVAHFKPVIEKQFSEQIYNGLWFSPLTDSLKLFIDSTQQYVEGDVRIKLFKGNAIVNGRQSPYTLYDEKLATYTKEDAFNQESAVGFIDIYGLPTQVNALLHGGYSNEQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSAA_STAES
Sequence: MKKIATATIATAGIATFAFAHHDAQAAEQNNDGYNPNDPYSYSYTYTIDAEGNYHYTWKGNWSPDRVNTSYNYNNYNNYNYYGYNNYSNYNNYSNYNNYNNYQSNNTQSQRTTQPTGGLGASYSTSSSNVHVTTTSAPSSNGVSLSNARSASGNLYTSGQCTYYVFDRVGGKIGSTWGNANNWANAAARSGYTVNNSPAKGAILQTSQGAYGHVAYVEGVNSNGSIRVSEMNYGHGAGVVTSRTISASQAASYNYIH
What is the function of this protein?
Not known; immunogenic protein.
What are the official names of this protein?
Staphylococcal secretory antigen SsaA.
What are the subcellular locations of this protein?
Secreted.
Protein: NU5C_PANGI
Sequence: MEQTYQYAWIIPFLPLPVPMLIGVGLLLFPTATKNLRRMWAFQSVLLLSIVMIFSINLSIQQINSSSIYQYVWSWIINNDFSLEFGYLIDPLTSIMSILITTVGIVVLVYSDNYMSHDQGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPVAANACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFKIFSNLIYNNEVNFLFVTLCAVLLFAGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLIPLFIVIPHIMNLISLVGIITVLLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSVIHSMETLVGYSPKKSQNMVFMGGLTKHVPITKTSFLFGTLSLCGIPPLACFWSKDEIINDTWLYSPIFAIIAWSTAGLTAFYMFRIYLLTFEGHLNVHFQNYKNTPFYSISLWGKEGSKRINKNFPLLTLLTMNNHEIASFFSKKTYQMDQNVRNITQPFITITYFGNKNIFSYPYESDNTMLFPILVLVLFTLFIGFLGIPFNQEGANLDILSKWLTPSINLLHQNLNNLIDWDEFAKDAIFSVSIAFFGIFIASFLYKPVYSSLQNLDLINSFVKIGPKRIFLDKIINGIYGWSCNRGYIDAFYATFFTGGIRGLAELTSFFDRQVIDGITNGVGVLSFFVGESIKSVGGGRISSYLFLYLSYVSIFLLIYYFLDL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TIMP1_BOVIN
Sequence: MAPFAPMASGILLLLWLTAPSRACTCVPPHPQTAFCNSDVVIRAKFVGTAEVNETALYQRYEIKMTKMFKGFSALRDAPDIRFIYTPAMESVCGYFHRSQNRSEEFLIAGQLSNGHLHITTCSFVAPWNSMSSAQRRGFTKTYAAGCEECTVFPCSSIPCKLQSDTHCLWTDQLLTGSDKGFQSRHLACLPREPGLCTWQSLRAQMA
What is the function of this protein?
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor.  Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16.  Does not act on MMP14.  Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1.  Plays a role in integrin signaling.
What are the official names of this protein?
Metalloproteinase inhibitor 1, Embryogenin-1, EG-1, Tissue inhibitor of metalloproteinases 1, TIMP-1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SNPC5_MOUSE
Sequence: MLSRLQELRKEEETLLRLKAALHDQLNRLKVEELALQSMINSRGRTETLSSQPAPEQLCDMSLHVDNEVTINQTTLKLSTRSPMEEEEEEEEEEEEEEESDS
What is the function of this protein?
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes.  Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes.  Recruits TBP and BRF2 to the U6 snRNA TATA box (By similarity).
What are the official names of this protein?
snRNA-activating protein complex subunit 5, SNAPc subunit 5, Small nuclear RNA-activating complex polypeptide 5, snRNA-activating protein complex 19 kDa subunit, SNAPc 19 kDa subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS3A_FELCA
Sequence: KNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity).
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: MATK_FILMA
Sequence: MEELKGYLEKSRSKQQHFLYPLLFQEYIFVLAHDHGLNVNGSIFYEPAEISGYDKKFSSLLVKRLITRMYQQNYLINSVNDSNQNRFVGHNKNFDSQMISEGFAVIVEIPFSLRLVSSLEEKKEIQKSQNLRSIHSIFPFFEDKLSHLICVLDILIPYPVHLEILVQILQCWIQDVPSLHLLRFFFHEYNNWSNLITPKKSNYYGFSKENPRLFLFLYNSYVVECESIFVFLRKQSSYLRSTSSGTFLERTHFHEKIEQHLVVLCCNDFQKTLWLFKDPFMHYVRYQGKSILASKGTRFLMKKWKSYFVNFWQCHFHFWSQSCRIHINQFPNFSLHFLGYLSSVPINPSAVKSQMLENSFLIDTVTKKFETLVPIISMIGSLSKAKFCNVSGNPISKPVWADLSDSDIIDRFGRICRNLSHYYSGSSKKQSLYRIKYILRLSCARTLARKHKSTVRAFLQRLGSEFLEEFFTEEEKVLSLILPRISYPLHKLYRERIWYLDIIRINDLVNHL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FIBA_VULVU
Sequence: TNSKEGEFIAEGGGVR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEF_DESPS
Sequence: MTENINAGIPLGKQVGHSETYDPSHLFPVARREARKSLGLADDLPFSGPDIWNAYELSWLDSKGKPCVALGEITFPCTSENIIESKSLKLYLNSFNLTRFTSTARVKEIIREDLSRVAGAEVEVKILTPEEFTEVTISAPEGSCIDDLELEEEINAYRPTANYLSTGPEETEEELYTNLLRTNCPVTGQPDWATVIINYRGKAIDQRGLLRYIISFRQHEGFHENCVERIFMDILNRCAPARLTVYARFTRRGGLDINPYRTTHAEHFVNLRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALS3_ARATH
Sequence: MAMVKEKEQNTKDKKLLVGVIWNFSAELKLTFMALLVLCTLATLLPFIPSSFSLSTSDFRFCISRFSSAVPLNTTTTVEESSSSPSPEKNLDRVLDNGVIKRTFTGYGSAAYNFVSMSAYRGGVNSFAVIGLSSKPLHVYGHPSYRCEWVSLDPTQDPISTTGFKILTDWGYGRIYTTVVVNCTFSSISAVNPQNSGGTLILHATTGDPTLNLTDSISVLTEPPKSVDFDLYNSTKKTKKYDYLYCGSSLYGNLSPQRVREWIAYHVRFFGERSHFVLHDAGGIHEEVFEVLKPWIELGRVTLHDIRDQERFDGYYHNQFMIVNDCLHRYRFMTKWMFFFDVDEFLHVPVKETISSVMESLEEYSQFTIEQMPMSSRICYSGDGPARTYRKWGIEKLAYRDVKKVPRRDRKYAVQPENVFATGVHMSQNLQGKTYHKAESKIRYFHYHGSISQRREPCRQLFNDSRVVFENTPYVLDTTICDVGLAVRTFELRTIGDRLLRTRQ
What is the function of this protein?
Involved in the biosynthesis of beta-1,4-galactan.  Beta-1,4-galactans are abundant polysaccharides in plant cell walls and are found as side-chain of rhamnogalacturonan I, which is a major component of pectin.
What are the official names of this protein?
Galactan beta-1,4-galactosyltransferase GALS3, Beta-1,4-galactan synthase, Galactan synthase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 92 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass membrane protein.