PharMolix/UniProtQA huggingface dataset:
Protein: CO6_BOVIN
Sequence: MARHSVMYFILLSALIDKSQACFCDHYPWSQWSSCSKTCNSGTQTRQRRIVTDKYYFENFCGQLCTKQESRECNWQTCPINCRLGDYGPWSDCDPCVQKRFKVRSILRPSQFGGQPCTEPLMTFQPCIPSKLCKIEEIDCKNKFRCDSGRCIASKLECNGENDCGDNSDERNCGRKKTVCSRSHNPIPGVQLMGMGFHFLAGEPRGEVLDNSFTGGVCRTVKSSRASNPYRVPANLENVNFEVQTKEDDLEADFYDDLIPLEDNKDQEALGSGLATSSFRVPIFYSSKRSQSSSHSSAFKQAIQASQKKASSFIRIHKVIKVLNFTMKTKDLQLSDVFLKALNHLPLEYNSALYSRIFDDFGTHYFTSGSLGGVYDLLYQFSKEELKNSGLTQEEAKNCIRIETKKRFLFVKKTKVEHRCTTNKLSEKYEGSFMQGSEKSISLVQGGRSAYAAALAWEKGSPVPEERVFSDWLESVKENPSVIDFALAPITDLVRNIPCAVTRRNNLRRAFREYAAKFDPCQCARCPNSGRPVLSGTECLCVCQSGTYGENCERRSPDYKSNAVDGNWGCWSSWSSCDATYRRSRTRECNNPAPQQGGKRCEGERRQEEHCTFSIMQNDGQPCISDDEDMKETDLPELESDSGCPQPVPPENGFIRNEKKQYSVGEEVEILCFTGFKAVGYQYFRCLPDRSWRQGDVECQRTECLKPIVPEGLTLSPFQTLYKIGDSIELTCPRGLVVNGPSRYTCSGDSWTPPISDSLSCEKDVLTGLRGHCQPGQKQLGSECVCMSPEEDCGHYSEEICVLDTTSSDYFTSSACKLLAEKCLNNQQLHFVHIGSCEEGPQLKWGLERIKLSSSSTKNESCGYDTCYNWEKCSATTSKCVCLLPSQCTKGGDQLFCVQIGSSANGKTMNICEVGAVKCAKREMEILHSGRC
What is the function of this protein?
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
What are the official names of this protein?
Complement component C6.
What is the protein family that this protein belongs to?
Belongs to the complement C6/C7/C8/C9 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MEND_KLEP3
Sequence: MSVSAFNRRWAAVILEALTRHGVQHICIAPGSRSTPLTLAAAENRAFIHHTHFDERGLGHLALGLAKASRQPVAVIVTSGTATANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPSQTISLPRPSQDIPARWLVSTIDQALGALHAGGVHINCPFAEPLYGDMDETGVEWQQQLGNWWQSDKPWLRQALQLESEKQRDWFFWRQKRGVVVAGRMSAAEGKKVAEWAQTLGWPLIGDVLSQTGQPLQCADLWLGNGKAVSELAQAQIVVQLGSSLTGKRILQWQATCEPDEYWLVDNLPGRLDPAQHRGRRLLASVERWLELHPAEKRQPWATVIPELSRQAWQAAVASNEPFGEAQLAQRIRRYLPEQGQLFVGNSLVVRLIDALAQLPAGYPVYSNRGASGIDGLIATAAGVQRASARPTLAIVGDLSALYDLNSLALLRQASAPLVLIVVNNNGGQIFSMLPTPQDERRQFYLMPQDVDFSHAAAMFGLAYHRPDDWQSLDEALAGAWRRAGATVIELAVNETDGTQTLQQLLAQVSRL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: Y539_PYRAB
Sequence: MIRYPAVAGQFYPEGETLVEMLEEFFRDLGEQGNSRKITAGVAPHAGYVFSGYTASRTYKAIYEDGLPETFVIFGPNHTGLGSPIAVYPEGDWVTPLGKVKIDSELAKEIVKLSKIADLDDLAHKYEHSIEVQLPFIQYIAEKAGTDFRIVPITLGIQDEDVSEALGRAVFEAAEALGRDVIVIASTDFMHYGSFYGYVPFRGRANELPNMVKEWDMRIIRRILDFDLKGMFEEIREMDHTMCGPGGVGAGIVYSRLMNAREAELLHYTTSFEVSRSTDAIVGYASIVMRR
What are the official names of this protein?
MEMO1 family protein PYRAB05390.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: KEFC_ECO57
Sequence: MDSHTLVQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLAASSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLIENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYICLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANC_NEIMF
Sequence: MQIIHTIRELRAWRKNAGKVAFVPTMGNLHEGHLALVREAKKRADNVVVSIFVNRLQFGQGEDFDKYPRTLQQDADKLEAEGVAVVFAPDEKELYPNVEQRYSVEPPNLQNELCGKFRPGHFLGVATVVSKLFNIVAPDVACFGKKDYQQLAVIKGLTEDLNFDVEIVPVDTGRAEDGLALSSRNQYLSAAERDEAPRLYRELKAVAESLAQGSLDYAGLEKRAVQSLTEYGWVVDYVEIRRADTLEVARAGDKKLVVLAAARLGTTRLIDNLEIKLP
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_MYCTU
Sequence: MPDEPTGSADPLTSTEEAGGAGEPNAPAPPRRLRMLLSVAVVVLTLDIVTKVVAVQLLPPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWALGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVILSIFGFDFDTVGRRHADGDTVGRRKADG
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSRB_STAAW
Sequence: MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMLRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: KLCA1_ECOLX
Sequence: MNTQDQPVTASLVAEAQRLDFLPTYFGPRLMMRGEALVYAWLRRLCERYNGAYWHYYTLSDGGFYLAPDLAERLEIEVDGNGFRGELSADAAGIVATLFALGQLAAEIAGTDAADALIDRYHFLRGFAAGHPEAAAIYRAID
What is the function of this protein?
Could be involved in overcoming restriction barriers during establishment after conjugative transfer.
What are the official names of this protein?
Antirestriction protein KlcA.
What is the protein family that this protein belongs to?
Belongs to the antirestriction protein family.
Protein: MPI1_LYMST
Sequence: MAGVRLVFTKAFMVTVLLTLLLNIGVKPAEGQFSACNINDRPHRRGVCGSALADLVDFACSSSNQPAMVKRNAETDLDDPLRNIKLSSESALTYLTKRQGTTNIVCECCMKPCTLSELRQYCP
What are the official names of this protein?
Molluscan insulin-related peptide 1, MIP I.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules.
Protein: FABZ_SHISS
Sequence: MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_BORT9
Sequence: MSEKLDKEDVLYKKRHSIAHVMAEAVIELFPNTKIAIGPPIKDGFYYDFDFEKHIIEDDLLLIEQKMREILKTGSSFVKEVITKEQALMLFKDEPYKIDLIHELDIADEISIYKSHNFTDLCKGPHIDNMGKIDPKAFKLISIAGAYWRGDEKNKMLTRIYGTLWNNEKDLKAYLKLREEIKRRDHRKLGRELDLFSVHEEIGPGLIFFHPSGARIRALIEDFWREEHFKNGYDILFTPHVGKSWLWETSGHLDFYKESMFEKMEMDKSNYYVKPMNCPFHIAIYNTGRHSYRDLPFRWAELGTVYRYEKVGALHGTMRVRGFTQDDAHIICTYDQVKFEVQEVLRFALYMWNKFGFTALKAYLSTKPEKSVGDEDDWIMSVKVLKEALINLGIDYDIDEGGGAFYGPKIDLKIIDSLGREWQMSTIQFDFNLPARFKMTYTAEDGKERQPFMIHRALLGSIERFFGILVEHYGGAFPVWLAPLQVVIIPVNNIVEEYALEVLSRFKKEGIRIKLDNDCNMRMNAKIRQYQSQKVPYMFIVGEKEVVEGKISIRTRTNEQINGLELKEALEFVKLKVSNKEIL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESPE_MYCTU
Sequence: MASGSGLCKTTSNFIWGQLLLLGEGIPDPGDIFNTGSSLFKQISDKMGLAIPGTNWIGQAAEAYLNQNIAQQLRAQVMGDLDKLTGNMISNQAKYVSDTRDVLRAMKKMIDGVYKVCKGLEKIPLLGHLWSWELAIPMSGIAMAVVGGALLYLTIMTLMNATNLRGILGRLIEMLTTLPKFPGLPGLPSLPDIIDGLWPPKLPDIPIPGLPDIPGLPDFKWPPTPGSPLFPDLPSFPGFPGFPEFPAIPGFPALPGLPSIPNLFPGLPGLGDLLPGVGDLGKLPTWTELAALPDFLGGFAGLPSLGFGNLLSFASLPTVGQVTATMGQLQQLVAAGGGPSQLASMGSQQAQLISSQAQQGGQQHATLVSDKKEDEEGVAEAERAPIDAGTAASQRGQEGTVL
What are the official names of this protein?
ESX-1 secretion-associated protein EspE.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=Localizes at or near the cell pole in (on average) 1 discrete spot upon overexpression in M.smegmatis (PubMed:22233444).
Protein: NPY1R_RAT
Sequence: MNSTLFSRVENYSVHYNVSENSPFLAFENDDCHLPLAVIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAVMCLPFTFVYTLMDHWVFGETMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYIGITVIWVLAVASSLPFVIYQILTDEPFQNVSLAAFKDKYVCFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKIRDSKYRSSETKRINVMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKISMNDNEKI
What is the function of this protein?
Receptor for neuropeptide Y and peptide YY.
What are the official names of this protein?
Neuropeptide Y receptor type 1, NPY1-R, FC5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GUAC_CHRVO
Sequence: MIKTELNYGDVYLVPKKTVVDSRKECDTSVQFGPRRFAMPVYPSNMKSVVSAETCELFAREGWFYTLHRFNVDAVAFTRYMQEQGLFASISVGVNDDTYEQLDALKAAGLSPEYMTLDIANAWCVKAERMIKHIKQHFPNTFLIGGNVATAEAARDLEAWGCDAIKAGIAGGRVCITKNKTGFHRPMVSTVRDCVAAVTIPVIADGGIVEHGDIAKALVCGATMVMAGSLFAGYDESAGDIVEIAGKHYKEYFGSASQFNKGAYVNVEGKKILVEYKGSMGKLLRELQEDLQSSVSYAGGTTLAALREVEMIQVYR
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: H3_VOLCA
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKTPATGGVKKPHRYRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSQAVLALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MUKB_SALHS
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLSLAELKDKLDEMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRLTLEAIRVTQSDRDLFKHLISEATDYVAADYMRHANERRVHLDQALAFRRELYTSRKQLAAEQYKHVDMARELGEHNGAEGSLEADYQAASDHLNLVQTALRQQEKIERYEADLEELQIRLEEQNEVVAEAAEMQDENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAISALSRAKELCHLPDLTPESAAEWLDTFQAKEQEATEKLLSLEQKMSVAQTAHSQFEQAYQLVAAINGPLARSEAWDVARELLRDGVNQRHLAEQVQPLRMRLSELEQRLREQQEAERLLAEFCKRQGKNFDIDELEALHQELEARIASLSDSVSSASEQRMALRQEQEQLQSRIQHLMRRAPVWLAAQNSLNQLSEQCGEEFTSSQEVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGAEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQIAEQLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPSLPIFGRAARENRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLSVAFEDDPEAEIRRLNGRRVELERALATHESDNQQQRLQFEQAKEGVSALNRLLPRLNLLADETLADRVDEIQERLDEAQEAARFVQQYGNQLAKLEPVVSVLQSDPEQFEQLKEDYAWSQQMQRDARQQAFALAEVVERRAHFSYSDSAEMLSGNSDLNEKLRQRLEQAEAERTRAREALRSHAAQLSQYSQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARQRRDELHAQLSNNRSRRNQLEKALTFCEAEMENLTRKLRKLERDYHEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQSVSFGQVNSVRLNVNVRETHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDEARRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTQTEDTPSEAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: PYRG_CHLT3
Sequence: MARSKIVKHIFVTGGVVSSLGKGILSASLGALLKSRGLRVAIQKYDPYINVDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFLDEATSRASNMTMGRIYKTVLDNERRGDYLGGTVQVVPHVIDEIKARMLDLAKKGSFDVVITEIGGTVGDIESLPFLEAMRQLKLQLGSKNLVNIHLTLVPYIKSAAELKTKPTQHSVKMLLEIGIQPDILVCRSEHPLSKDIKHKIGLFCNLSDSDVVGLCDAETIYEVPLVLHEEKIDSLVLKKLMLKSPKPADIKDWKDFSGKVKFPKDGVVEIGVCGKYTKYPDAYKSIVESFIHAGAANNVKVKVRWMHSEDLEQKDCKVNEMLQGISGILVAPGFGERGIEGKIEIVKIARERNIPFFGICLGMQCATIEYARNVCGMEGAHSTEFVKKTKYPVIDLMEHQRSVKQKGGTMRLGSYPCILEENTNAFAAYGKNLINERHRHRYEFNNQFKEELSAKGLVIAGASPDGELVEIIELKGHRWFVGVQFHPELKSRVHKPHPLFISFVAEAKKFRDEMAVHHYETSSVETV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: KELC_ANOST
Sequence: MLSFIQYTLGIMSSLGNGNNQHNINSNTGSSQNSAAEGTMERGSCILVRYASQNSLDESSQKQLPRSNGKEKTTGAYRNNIHTQRSFEAMNMMREQNLLCDVVLVAEGIEIPAHKMVLASCSPYFYAMFTGFEESRQDRITLQGVDPRALQLLIEYVYRAVVEVTEDNVQILLTAANLLQLTDVRDACCDYLQTQLDPSNCLGIRDFADIHGCIDLLNYAETYIEQHFSEVVQFDEFLNLTSDQVAHLIKSDRLSVPTEEKVYECVITWIQYDVNGRQHHLAELMEHVRLPLLSQDYLVQYVEKEQLMKGDLQCKDYIIEALKYHLLKGEQKTCFKTPRTIPRQPVGLPKVLLVIGGQAPKAIRSVECYDLREEKWYQVAEMPTRRCRAGLAVLGDKVYAVGGFNGSLRVKTVDVYDPVLDQWTTSHNMEARRSTLGVAVLNNCIYAVGGFDGSTGLSSAEMFDPKRQEWRLIASMSTRRSSVGVGVVNGLLYAVGGYDGASRQCLASVERYNPSTDTWTQIAEMSARRSGAGVGVLDNILYAVGGHDGPLVRKSVEAYDPATNTWRAVGDMAFCRRNAGVVAHNGMLYVVGGDDGLSNLASVEVYSPESDSWRILPSSMSIGRSYAGVAMIDKPLUSEQQGARVATKQSYASHHPTGTIYSRYANCAALQQAQNEAAAGQAAGFGNDDENSQAEGLNPEPANSNNSAPNGNNVHYENIYESIEQFAPLNGGNGGNGGAHAGIPAGSNPLQYAVLNQPQPGPSGLGPGQAHRSLGGERGAVGGGGGGGGAVGGGCIPPPPPSMLHSMQQLYHPMAYRNELYDRTAGYDVPRGRPAPSYYQNQPPTGPSANGRCPNLHLDLNRVRYPSGASAQQQQRTPRQRSFDDTESYHYYRCQNQSNGTAKYDNLYERVREEPAYQNTGSFAPAANRAAGLFGRFDVIGHGVGRIERHLSSSCGNIDHYSLGGHYAVLGHSHLGTMGHIRLNQSNSSSASSASPYGANGPATTSQPNPTKDSSSVNVKSFLSCLGGENSQSMNNLNKSSAAHGTASGSAPAANGNEATLPGSISGGASGGGAGGAGSSGGNGGQGSSIMGGLASAAAVGVNGTGASTSTTLGGKSTGAIPKISRKSKQSQQQGPSDPTAGTSAPQSLAGGNGLPPVDVSLGAPADPMYANGCGGRVTKPSLQWLLVNKWLPLWVGQTPPDYKFIDFNFMFSRNCDGCSSAGGSHGQQQQQPQELVRYGTIDQADYIPPAREYPTMTGSYPRVLRNTPQLARLREHEYENVPLNDPPPGRGLRGIASPLQVGRARSESPSRPPGSDPLRTWAFDFENNTFRPARSPALATSSGLAINREKPREVRRITDGTFGARDLAQPDTEKPGPSGLASKLALLKQPEPDKEDGRLSSASSSSDSDNFAIESLAAESSGGQPDEEEEEEGGSTRSGVGRRDDGGRVVGNSTEKENVGSSSNETSDSLNYDGPASADRSLSEDEVEAARPDNTASE
What is the function of this protein?
May play a role in organizing the actin cytoskeleton.
What are the official names of this protein?
Ring canal kelch homolog, Kelch-like protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: VE6_PAPVE
Sequence: MCGECYAYLTCIWCKKGLDKVDAKRCHEKKIRIACRNGKHCAVCTSCLENGLYLERSLFPGRPIYPGDLYEPDPWVMFNDIRCMYCGGCLTRDEKERHRLFCEDFWIFRHQVRGRCYLCTRHGSRPPYKETPAAV
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: GCS2_RALPJ
Sequence: MSLEPFSKSEALTFGVELELQLVNRHDYDLASASPDLLRMLKGKEYPGDIKPEITDSMIEISTGICHSHDEALWQLREMRDRMAEAATALNIGICGGGTHPFQQWSQRQISQSPRYQYISDLYGYLAKQFTVFGQHVHIGCPNPDDALYLLHAMSRYVPHFIALAASSPFVQGVDTGFASARMNSVSAFPMSGRAPFVLTWDAFIAYFDKMHATGVIESMKDFYWDIRPKPEFGTIEVRVMDTPLTVERAAAIAAYIQALGRWLLLDRPFMPVEDDYLVYTFNRFQACRFGLAGEYVDPATGNRGALADHILETSKLLSAHAEALSSEGALDMVREVVEARDADAEWIRAAQRETRNLHETVRRGCGRWTQAATQPA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: Y924_THET8
Sequence: MEGRTLEEVQEEVFKRHGVLVPKKELEDLAKALEEAGLLLTEKVEARLKEEEEKLKRERPMRLAGLSYPEGEREARAFLEAFRASYPGEGEEARVLLMPHLEPSRVPEVYGAALAALEKTPPPERIYLVGVAHRPLKEKAAALPVPFQTPFGPALPDLPALQALDALLPFELFNTPLAFREEHSLELPLFFLKGRFPEARVLPLLVARRSPELGEALKVVLRDFPGLLVLAVDLSHVGPRFGDTPLTRTLAEEARRRDLGFLERLAEGEPEAALAFLGANPTRIDGVEVVASLLPLLRERKGKVLAHRLDLEAPTLSAVGAGTLVL
What are the official names of this protein?
MEMO1 family protein TTHA0924.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: RISB_BACSU
Sequence: MNIIQGNLVGTGLKIGIVVGRFNDFITSKLLSGAEDALLRHGVDTNDIDVAWVPGAFEIPFAAKKMAETKKYDAIITLGTVIRGATTHYDYVCNEAAKGIAQAANTTGVPVIFGIVTTENIEQAIERAGTKAGNKGVDCAVSAIEMANLNRSFE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.  Is able to use the non-natural R enantiomer of 3,4-dihydroxy-2-butanone 4-phosphate as a substrate, but with less efficiency than the natural S enantiomer.  Cannot use unphosphorylated 3,4-dihydroxy-2-butanone, 3,4-dihydroxy-2-butanone 3-phosphate or diacetyl as substrates.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase, Heavy riboflavin synthase beta subunit, HRS beta subunit.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: HEM1_ACIB5
Sequence: MSFFALGVNHQTASVELREQIAFNAERLSNLLAEQRHHESLKDLVVVSTCNRTEVYAMAEDAESLLKWLADANNIDVKQLIHHVYRYENAQAITHLMRVASGLDSLMLGEPQILGQVKSALALSKEAQTVSPELNSVFEYAFYAAKRVRSETAVGSHAVSMGYAVAQLALQVFSKPEKLTVMVVAAGEMNSLVAKHLAEMGVAKMIICNRSRERADQLAQEIAHQVEVEIIDFSDLAENLYRADVVSSCTGSLHQVIAYADVKTALKKRRYQQMLMVDLAVPRDIDPKVESLDGVYLYGVDDLQSVIDENLAQRRQAAVEAEVMVNQLATQLITHQKVKEAGSTIHAYRQHSEEISQRELTHALEALHHGGNPEQVLQQFAHRLTQKLIHPTSMLLREAAKAESPDYFEWLQQHLQDVFDHERKPKR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SUCC_RHOP2
Sequence: MNIHEYQAKAVLREFGVPVSHGYPIFKASEAEAAATKLGGPVWVVKSQIHAGGRGKGKFKEASAGDKGGVRLAKSVDEVKTYAEQMLHATLVTVQTGPAGKQVNRLYIEEGSEIDKEFYLSLLVDRATSRISFVVSTEGGMSIEDVAHDTPEKIVSFTVDPATGIMSHHGRAVANALGLKGDQAKQAESLVTKLYTAFLAKDMEMLEINPLVLTKQGDLKCLDAKMSFDGNSLYRHADIQGLRDESEEDAKEIEASKYDLNYVTLDGTIGCMVNGAGLAMATMDIIKLYGMTPANFLDVGGGASKEKVTAAFKIITADPNVKGILINIFGGIMKCDIIAEGVVAAVKEVGLDVPLVVRLEGTNVEAGKKIIKHSGLNVLPADNLDDAAQKIVNAVKGA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.