PharMolix/UniProtQA huggingface dataset:
Protein: PHMF_PHANO
Sequence: MAEAFTTVPAKSSPARFRYTKANPVKDPTTSFAGKTILITGPNAGLGFEAATKFARLGASKLIFGVRSLERGQEAKTKIEQLTKCKRDAIQLVQLDMGSYASIEKFAKSVTDEFPVIHAAVLNAGVAPPSYKLSQEGWEMSLQVNVISTAYLAILLLPKLRESGRAIGEPAYLEFVSSTGHGDVTTESVRDGKSILKKVNDPANFKFTAQYQITKLLEIWAMEHIAAKTSPKEVIVNSACPGLCKSSIGRDFGIVLRGLDAVFKGIFAQTAEAGSRILVSAVTAGTDSHGGFWALDAVSVPGELVTSDEGKALSKQFWAEVLDVLRKQNADVEAILNG
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of the mycotoxins phomacins, leucine-derived cytochalasans with potent actin polymerization-inhibitory activities and monocot-specific antigerminative activities (PubMed:31815421).  The first step in the pathway is catalyzed by the hybrid PKS-NRPS phmA, assisted by the enoyl reductase phmE, that are responsible for fusion of the leucine precursor and the polyketide backbone to produce a 2-pyrrolidone intermediate (PubMed:31815421).  The polyketide synthase module (PKS) of phmA is responsible for the synthesis of the polyketide backbone and the downstream nonribosomal peptide synthetase (NRPS) amidates the carboxyl end of the polyketide with the leucine precursor (PubMed:31815421).  Because phmA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase phmE (PubMed:31815421).  Reduction by the hydrolyase phmG, followed by dehydration and intra-molecular Diels-Alder cyclization by the Diels-Alderase phmD then yield the required isoindolone-fused macrocycle (Probable).  A number of oxidative steps catalyzed by the tailoring cytochrome P450 monooxygenase phmB, the FAD-linked oxidoreductase phmC and the short-chain dehydrogenase/reductase phmF, are further required to afford the final products, phomacin D and phomacin E (PubMed:31815421).
What are the official names of this protein?
Short-chain dehydrogenase/reductase phmF, Phomacin biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: JCAD_BOVIN
Sequence: MYSVEDLLISHGYKLSRKLPAPHEDDGERRQPARTTVPAGPGLLNGCDDGPAALPRGKASPGTGLLSDPESRRLGPRGHGERPSTAAAARISEAGFYHQPVLAWSSQPLTGRSHAYWRRREQEAREDPGGRGPVPSLPTHPREGPWEVGGRSEHVMKKAVWEDELGMAGPARWQDVSVRSWNQPPRLGRQMSDGVGEKLFQDLYPFMLGEHGLTSQSKGKSQSLPRVLSPESLSCMEVPIPLSDGHLPGVPKVPLQPPNCASNLESTRNPKKAGTSAPLPQPRFGRPLKPPSYGSQPHSKAGAENGSYTDSRQLDPGAAHSARTNSARQDLYGPDPGLEPPVYVPPPSYKSPPQPAAHPCPEEAVSRHEGRGRRVPQHPMERPAAGGQPLSGSRGAGSEWGASPCSPVGVPPQPHHTTAYDGSILIIPFDDPRIRHIKLPRPHGFWEDVKLDGAVPAPDPRSLQQEGAVWGPSGKERGPAPADPSPSWLWGQPPRNGENGSSPDQRDPCIVTQRKQPDVSGSPQEYPESLVSSPSPQGESSCEMQTQLRKFEAGLQPKRSSKKKTSETIFCLVSIPVKSESQLPGTDTNNNDLKQSASLQEQSVLSLSSTDLELQALTGSMATRTELPRPDPGGPGRGRQADDLRFPSPAKHRALAWPGPWPGHHFRDQQTQTSFAHEPQSLQPLPGERPGGSPDPVLPPRCLDPAPFEVQMHMALASSDPNQRPGAHSPKSQGSLSPSSNSAFSGSSWPRNQGPVPRASLGQQGSDGPGRRASPVSRGEVIKGETTGPCNSRQLFGQFLLKPVSRRPWDLISQLESFNKELQEEEGSSGSSSDGSGSEDSDTELPWGSCARPAPQLPGLLKDIVPEDPRTRPGRVKSKSESWSEEGRPRSPRPWQAEGRGSVWLSPPGSWIAEDGDREVEDRVAQLAVSPRPVKRAISSGLNDAKPEPPPDPAEQREPLPSQELPGSRGAVELSAAGPPRAGGGEQGSTRAPLSLAGKSRGLSAPDLRSVGLTLVQEHSTSQLAGSPGDANAIEIPPNESLEARAARILGIEVAVESLLPGAQRAGQRRHPEPDGSALRPESPRQEAAASLAQPNESTAPADAFYGRRKCGWTKSPLFVGERDSTRQVPRASEPADVDGAVPTKAPETPPSPLESQPFLPKDVETKPPFRSTLFHFIERTPNLAFSEKKLRNTSRVIESLQEKLVSPPRKADPDRLTRMKEVSSVSRMRLLTSRAADSAEEPKAERGPGAWLGGLVAPSAGHKLSDPQGALSLEADGHPAARRENGGRDFWCPDSYDPSRVERV
What are the official names of this protein?
Junctional cadherin 5-associated protein, Junctional protein associated with coronary artery disease homolog, JCAD.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Note=Colocalizes with CDH5/VE-Cadherin in endothelial cells but not in epithelial cells.
Protein: YDHB_BACSU
Sequence: MLIILVMFLLGIILGFIGAGGAGFVIALLTLLFHIPIHTALGTSLAGMAFTSLSGAYSHYREGNIQMKIGLIVGGFAAVGSFFGAKLTSFIPADLLHYLTAGMLFLSAILILIRLFILKEKAQVNQSTLSTYTRAVILGIAAGVLSGTFGIGSAPFIQIGLMIMLNLSIRHSVGTTMLVIIPLAVGGGIGYITEGFVDYVLLVKVLVGTMCGAYVGAKFTNLMPKVVLKSAIFLTPAIAGLLLLF
What are the official names of this protein?
Probable membrane transporter protein YdhB.
What is the protein family that this protein belongs to?
Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH601_CHLAA
Sequence: MPKQLYFNEEARRALKRGVDLVADAVKTTLGPRGRNVAIDKKFGSPTVTHDGVTVAKEIELKDPFENMGAQLLKEAATKTNDVAGDGTTTATVLAQAIVTEGLKVVAAGANAMLLKRGLDRGAEALVAAIKASAVPVRDRADIAHVATNSAADSEIGELIAEVMEKVGKDGVITVEESKGVTFEKEYTEGMQFDRGYISGYMVTNVERQEAELDEPYILITDKKISSIQEILPVLEKVLQVTKNFVIIAEDVDGEALATLVVNKLRGTINALAVKAPGFGDRRKAMLQDIAILTGGTVISEEIGRKLDSATIEDLGRARKVIATKDDTTIIEGRGDEAAIRARIEQIRAQIATTTSDFDREKLQERLAKLAGGVAVIKVGAATEPELKEKKHRVEDALSATRAAVEEGIVPGGGVALINAIPALDNVQVAHEDEKVGLQILRRALEEPLRILARNAGEDGSVIIANVRRLQEEKGDKTIGYNVLTGQYGSMIEQGIIDPVKVTRSAVQNAVSIAGMILTTEALITDIPEDKPAATPGAGGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABPL_LETCA
Sequence: DSANFDEYMKAIGIGFAMRQIGSVTKPTLIISAEGDHVTLKTTSTFKNMEWNFTLGEEFDETTADERKTKSTFTVDGDKLVQVQRWEGKETTISRAVSGDSMVATCSIGDVVCA
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
What are the official names of this protein?
Fatty acid-binding protein, liver, Liver-type fatty acid-binding protein, L-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_PARMW
Sequence: MVRVRLAPSPTGTLHIGTARTAVFNWLYARRQQGSFLLRIEDTDKERSKPEYTQNILEGLRWLGIDWDEEPLIQSEQVQQHRAAIETLLQKGLAYRCYANEAELDAMREAQKASNQAPRYDNRHRNLTPEQEAAFQSEGREAVIRFRIDDNAEIRWNDMVRGAMSWRGADLGGDMVVARRAPADQIGDPLYNLVVVVDDAAMAISHVIRGEDHIANTAKQLLLYEALDLPAPTFAHAPLILNAEGRKLSKRDGVTSINDFRTMGYTAEAIANYMTLLGWSVPEGMEERFTLPEAAAVFSFDRVNKAGARFDWDKLNWLNGQVLHALPAQQLLDDLRPLWAEQGWTLPDDSSWGLELCELLGPSLTLLKEGVEQATPFFKCPDLEDDGVRQLEADGARTAVAQLLQILEAEPWDGKDTDRAKQLLADAAKGAGVKKGVVMKSLRAALLGRLQGPDLITTWCLLARIGEDLPRLQRCLA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_METC4
Sequence: MGKVIGIDLGTTNSCVAVMEGTQPRVIENAEGARTTPSIVAFTDDGERLVGQPAKRQAVTNPERTFFAIKRLIGRTYDDPLTQKDKGLVPYKIARGDNGDAWVEADGKKYSPSQISAFTLQKMKETAESHLGQPVTQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKKKAGTIAVYDLGGGTFDVSILEIGDGVFEVKSTNGDTFLGGEDFDNRVVEYLTAEFKKEQGIDLTKDKLALQRLKEAAEKAKIELSSATQTEINLPYITADASGPKHLALKLSRAKFESLVDDLVQRTIEPCRKALKDAGVSASEIDEVVLVGGQTRMPKVQEVVKAFFGKEPHKGVNPDEVVAIGAAVQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIDRNTTIPTKKSQVFSTAEDNQNAVTIRVFQGEREMAADNKLLGQFDLVGIPPAPRGMPQIEVTFDIDANGIVNVTAKDKATNKEHQIRIQASGGLSDADIEKMVKDAEANAEADKKRRELVEVKNQGESLIHATEKSVAEYGDKVSAADKGAIESAITALRSALEGEDAEGIKAKTNDLMQASMKLGEAMYAASQTEGAPGADGAASTDEKKDDVIDADFQEVDENERKKRA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SYGB_PSEE4
Sequence: MSAQDFLVELGTEELPPKALASLGDAFLAGIEKGLQAAGLNYTSKQVYAAPRRLAVLLRQLDVQQPDRSINIDGPPRQAAFDAEGNPTQAALGFAKKCGVELSDIDQSGPKLRFSQHIPGKATASLLPTIVEDSLNDLPIPKRMHWGASREEFVRPTQWLVMLLGDQVVDCTILAQKAGRESRGHRFHHPENVVITTPANYVEDLRKAYVLADFAERRELISKRTAELAMQQEGSAIVPPALLDEVTALVEWPVPLVCSFEERFLEVPQEALITTMQDNQKYFCLLDSEGKLLPRFITVANVESRDPKQIVEGNEKVVRPRLTDAEFFFKQDKKQPLESFNERLKNVVFQAQLGTVFDKAERVSKLAAFIAPYIGGSAANAGRAGLLSKCDLASEMVGEFPEMQGIAGYYYALNDGEPQDVALALNEQYMPRGAGAELPQTLTGAAVAIADKLDTLVGIFGIGMLPTGSKDPYALRRAALGVLRILIEKQLDLDLTTAVEFAVKQFGTKVKAAGLSEQVLEFIFDRLRARYEDEGIDVATYLSVRALKPGSALDFDQRVQAVQAFRKLPEANALAAANKRVSNLLGKAEGAIADQVEPKYFDNANEFSLYSAIQQADQAVQPMASARQYNEALARLAALRDPVDAFFEAVLVNAEDAKVRANRYALLSRLRGLFLGVADISLLG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_XANCB
Sequence: MKKPLRWLAALTALLLPLSAFAQQQGLTIDIVGGSASATPITVVPMPYQGSGTAPQTDVSAVVSADLDRSGQFRTLPAAQIVEKPTRGTEVQFQTWRTLKQNYIVVGRVMDAGEGAYRVEYELFDVAKGERLLGLAMTARANAMRDVSHQMADAIYEKVTGVRGAFWTRIAYVTASGSGGSMRYALMVADSDGYNPQTIVRSAEPLLSPNWSPDGKKLAYVSFERGNSSIYLQDIASGARELVSSFRGINGAPSFSPDGRRLALALSRSGNPEIYVMDLGSKQLTQLTNHFGIDTEPTWAPDGGSIYFTSDRGGRPQIYQVAASGGSANRVTFQGNYNATASVSFDGKKVAVAQGSGNTYRIAMMDRSLGSPSWSTLSPGSLDESPSFAPNASMVLYAAREGGRGVLYAVSADARVRQRLVLADGDVREPAWGPYRTAH
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NU3M_ASCSU
Sequence: MLVLVMVVLFTLVLLFVFYIGNFVLSCKDFYKNKISSFECGFVSIGKIQNSFSIHFFIMMLMFVIFDLEVVMFLGILVSDLNSLISFFMLLMFIFGGFYMEWWYGKLVWLI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: XERC_MYCBT
Sequence: MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTVPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_BRUMB
Sequence: MWEKVDQLTPSRYSPYRFFSAQEWAAFRADTPLTLTYEEVKRLRSLGDPIDLDEVRRIYLSLSRLLYAHVEASQLLFRQRQQFLNMEESYKTPFIIGVAGSVAVGKSTMARILKELLARWPSSPKVDLVTTDGFLYPNAVLREQNMMERKGFPESYDIGAVLRFLSAIKAGMSRVRAPLYSHLSYDVLPGEYQIVDKPDILIFEGINVLQVRDLPEDGKMVPFVSDFFDFSIYIDADPRLIHKWYIDRFMRLRETAFRDPQSFFHRYSQLSQEAARSIAEGLWQNINLKNLNENILPTRPRADLILRKGSDHLIEEVALRKI
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_STRP6
Sequence: MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVGVLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVDQTMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISLFERTSPLNFTEDGLCRFSFKVACSKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEIADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKVIAILEKRDQEYKPKKVLI
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: CDK1_CARAU
Sequence: MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYKNTFPKWKSGNLASTVKNLDKNGIDLLTKMLIYDPPKRISARQAMTHPYFDDLDKSTLPASNLKI
What is the function of this protein?
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins.  Required in higher cells for entry into S-phase and mitosis.
What are the official names of this protein?
Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: GG6L6_HUMAN
Sequence: MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAELQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH
What are the official names of this protein?
Golgin subfamily A member 6-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the GOLGA6 family.
Protein: MNMG2_CALS4
Sequence: MRYIAGEYDVCVVGLGHAGSEAALASARLGLATVGFATNLDAIALMACNPSIGGPAKAQLVREIDALGGEMAVNTDKSLLQMRTLNTSKGPAVRSLRAQVDKKLYQANMKHTLERQKNLDIKQAEIVDILVENNKVVGVVTKLGAIYKCKACIITTGTFLRGRVIIGEVGFESGPSGLFPAKELSEAIKRLGFKMMRFNTSTPPRVDKRTVDFSKMIMQPGDEVITPFSFMHDKIEIEQIPCWLTYTNEKTHKIIRDNIHRAPLYTGEVEGVGVRYCPSIEDKVMKFPHRDRHQIFVEPEGRDTYEMYIQGLFSSFPEDLQMEILSTIPGLENAKIMRPAYAIEYDCIDPTQLKATLETKLVEGLYFAGQVNGTSGYEEAAAQGLMAGINAALKILGKPPLILDRSQAYIGILIDDLVTKGTNEPYRMLTSRAEYRLILRQDNADFRLTEIGKEIGLVTEERYEKFLRKKIQLEKEMMRLPTVMVRPTEEVNNFLISRGSTPLVSGVDLYTLLKRPEIDYKSTKFLDPTRPDDILDSVAEQIDINIKYEGYILKQLRQVEQFKAMENKKIPEDIDYYQVHGLSNEAKEKLSKIRPTSVGQASRISGVSPADISVLLIYLQQMRRKRSDEAKIN
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG 2, Glucose-inhibited division protein A 2.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPA_PSEAE
Sequence: MSQSNTLTVQILDKEYCINCPDDERANLESAARYLDGKMREIRSSGKVIGADRVAVMAALNITHDLLHRKERLDQESSSTRERVRELLDRVDRALANPADAGEA
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division (By similarity).
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid- cell.
Protein: VIP2_PONAB
Sequence: MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPMKEILERVSLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPFVINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVFQKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLAFKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSIPLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSGKLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFFSGINRKVQLTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEELTPSGSVSLIKSMHLIKNPVKTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKAKNGRYDISKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCTPLVRKIRSDLQRTQDDGTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGALCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGCEEDKNLPSGYGYRPASRENEGRRPSKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHRKSPLPRSRKMATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSLAFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQDYARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSLKQVDEFLASIASPSSDVPRKTAEISSTALHSSPIMRKKVSLNTYTPAKILPTPPATLKSTKASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK
What is the function of this protein?
Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4.  PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation.  Phosphorylates inositol hexakisphosphate (InsP6) at position 1 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4.  Alternatively, phosphorylates PP-InsP5 at position 1, produced by IP6Ks from InsP6, to produce (PP)2-InsP4.  Required for normal hearing.
What are the official names of this protein?
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, Diphosphoinositol pentakisphosphate kinase 2, Histidine acid phosphatase domain-containing protein 1, InsP6 and PP-IP5 kinase 2, VIP1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family. VIP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MTF1_PLAOK
Sequence: MRFIGSKVNLLDNIQEVIEENVKDDAHVFMDLFSGTGIVGENFKKDYQVLSNDSLYFSYILLKAKIENNSIPNFSELKKIGIKEPLHYLENEEFEISHEFFLTHNYSPYMGCERMYFTVENASRIDFIRLTLNRWKNESLINELEFAYLLAILIEAVPFISNISGTYGAYLKHWDKRALGKLKLRTLDIGNNHYANKTYNEDANSLIEKVYGDILYIDPPYNGRQYISNYHLLETIALYDYPEIYGKTGLRPYVESKSLYCQKKEVGNAFNHLIEKANFRHILVSYSSEGLLLEEEIESILKSHGLPETYRIYKMPYRKYKSKHKQEASELHEYIFYIQKDIALTNSVKSNKKIEVGKHKTNSYIKSPLNYVGGKHKLLNQIVPLFPDKIDTFVDLFSGGFNVGINVNANKIIATDINTYVVEVLDTMKKTSVEEVIAHIERRIEEYGLSKSNEEGFKAFRNYYNKTKKPLDLYTLICYSFNYQFRFNNNQEYNNPFGRERSQFSPALKKKLVLFIEALHEKNVQFVCSEFEHFNFSQLDQNDLVYCDPPYLITTGSYNDGNRGFKDWNRLQEIKLLDILDHLNSKGVYFALSNVLSHKGLENELLLEWSKKYNIHHLQHSYSNSSHNTTRGESQEVLITNYTNYTK
What is the function of this protein?
An alpha subtype methylase that recognizes the asymmetric double-stranded sequence 5'-GGATG-3', methylates A-3 of both strands, and protects the DNA from cleavage by the FokI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.FokI, M.FokI, Adenine-specific methyltransferase FokI, Modification methylase FokI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: ARGI_BRUME
Sequence: MHCKILGLPVQEGTGRKGCNMGPDSYRAAGIADAIRELGHECTDLGNLAPAAQRPLQHPNHAIKALPYAVAWIEAISEAAYRESAEGFPIFLGGDHLLAAGTVPGIARRAAEKGRKQFVLWLDAHTDFHTLETTTSGNLHGTPVAYYTGQKGFEGYFPKLAAPIDPHNVCMLGIRSVDPAEREAVKKTEVIVYDMRLIDEHGVAALLRRFLERVKAEDGLLHVSLDVDFLDPSIAPAVGTTVPGGATFREAHLIMEMLHDSGLVTSLDLVELNPFLDERGRTAAVMVDLMASLLGRSVMDRPTISY
What are the official names of this protein?
Arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: ATPF_FRAP2
Sequence: MDINITLIGQMITFAIFVGFTMKFVWPPLRKALDERREKIAEGLASADRASRELEVAKRQSAEILREAKAKATEIVENAYVRAHKVDEQAKEEAIAAADKIKSMAMAEIEQEKVKAKEELKHEVVSLAMAAASKIISANVDEQSSKKILKDFVEKV
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NUOA_ROSCS
Sequence: MLADYAFIGVFFIGAVIFPLVPLVAAYFLGPKRPTPIKLDTYECGLEAVGDIRVQFKIQYYLYALAFVIFDIEVVFLYPWAVAYGQIGLFALIAMAIFLVILVGGLVYEWKKGALEWV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECA_STRPG
Sequence: MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLAEHPELFDEIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.