PharMolix/UniProtQA huggingface dataset:
Protein: TPH_AMOLO
Sequence: MFPLKKSLLLLFFLATINLSLCEQERNAEEERRDEPDERNAEVEKRFLPIVGKLLSGLSGLSGK
What is the function of this protein?
Antimicrobial peptide with activity against Gram-positive and Gram-negative bacteria and against fungi (PubMed:19843479).  Has been tested against S. aureus (MIC=2. 5 ug/mL), B. pumilus (MIC=7. 5 ug/mL), B. cereus (MIC=75. 0 ug/mL), E. coli (MIC=5. 0 ug/mL), B. dysenteriae (MIC=20. 0 ug/mL), A. cacoaceticus (MIC=60. 0 ug/mL), P. aeruginosa (MIC=2. 5 ug/mL) and C. albicans (MIC=2. 5 ug/mL) (PubMed:19843479).  Also shows a weak hemolytic activity (PubMed:19843479).
What are the official names of this protein?
Temporin-ALh.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DEOD_LISIN
Sequence: MSVHIEAKQGEIAETILLPGDPLRAKYIAETFLEDVVLFNQVRGMLGFTGTYKGEKVSVMGTGMGIPSISIYVNELIQSYDVKNLIRVGTMGGIQADVKVRDVVIAQAASTDSQINRNTFAGVDFAPVADFSLLKKAYDAGVEKGLSLKVGNVFSADRFYNDQLDKQQLADYGVLGIEMEAAALYTLAQKYGRRALAILTVSDHIFTGEETSAEERQTTFNDMIVVALEAAIK
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: RNZ2_GORGO
Sequence: MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVVRLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIELAVRPHSAPEYEDETMTVYQIPIHSEQRRGRHQPWQSPERPLSRLSPERSSDSESNENEPHLPHGVSQRRGVRDSSLVVAFICKLHLKRGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHEGREILAEELCTPPDPGAAFVVVECPDESFIQPICENATFQRYQGKADAPVALVVHMAPESVLVDSRYQQWMERFGPDTQHLVLNENCASVHNLRSHKIQTQLNLIHPDIFPLLTSFPCKKEGPTLSVPMVQGECLLKYQLRPRREWQRDAIITCNPEEFIVEALQLPNFQQSVQEYRRSVQDVPAPAEKRSQYPEIIFLGTGSAIPMKIRNVSATLVNISPDTSLLLDCGEGTFGQLCRHYGDQVDRVLGTLAAVFVSHLHADHHTGLLNILLQREQALASLGKPLHPLLVVAPSQLKAWLQQYHNQCQEVLHHISMIPAKCLQEGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGCALVHTSGWKVVYSGDTMPCEALVRMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAISVGMRMNAEFIMLNHFSQRYAKVPLFSPNFNEKVGVAFDHMKVCFGDFPTMPKLIPPLKALFAGDIEEMEERREKRELRQVRAALLSGELAGGLEDGEPQQKRAHTEEPQAKKVRAQ
What is the function of this protein?
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity.  Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.  Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
What are the official names of this protein?
Zinc phosphodiesterase ELAC protein 2, ElaC homolog protein 2, Ribonuclease Z 2, RNase Z 2, tRNA 3 endonuclease 2, tRNase Z 2.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Nucleus. Note=Mainly mitochondrial.
Protein: RL4_AQUPY
Sequence: MKIGDVEVRDDVFNVKVKKHVLWEVVKWQLAKRRQGTHSTKTRGEVAYSGRKILPQKGTGNARHGERGVNIFVGGGVAHGPKPRDYEYPLPKKVRKLGLKMALSDKAQNDAIMFVDNIDLGEQPKTKKAVEFLKNLGVDKETLLIVIPEKNEVLYKSFRNLQNVRVLLPEGLNVYDVLWANKLVIHKECLDRIYKKVEA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RL16_LACAC
Sequence: MPLVPKRVKHRREFRGKMRGAAKGGKYIAFGEYGLEALESHWITNRQIEAARVAMTRYMKRGGKVWIRIFPQKSYTAKGVGVRMGSGKGAPAGWVAVVKREKILFEIGGVSEEVAREALRLASTKLPIKTKFVTRSSEVGGESNEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: HTPG_SHEFN
Sequence: MSQQETHGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTDDTLYEGNGDLRVRVSANKEKGTVTISDNGIGMTRDSVIEHLGTIAKSGTKEFFSNLSGEASKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHAANEGVLWESEGEGSFNVESITKNERGTEIVLHLRDEETEFADDYRLRSIITKYSDHISVPVQMWNEGTPESDGPDGEKVAATEGEWKVMNKATALWTRNKSDITEEEYQEFYKHISHDYSDALKWSHNRVEGKQEYTSLLYIPAKAPWDMWNRDHKHGLKLFVQRVFIMDEAEQFLPTYLRFVRGLIDSNDLPLNVSREILQDNQVTTAMRVGITKRVLGMLEKLAKDEPEQYQSFWAEFGQVLKEGPAEDFANKERIAGLLRFASTHDNSAATTVSLEAYIERMKAGQDKIYYIVADSHEAAANSPHLELLRKKGIEVLLLSERIDEWLVNHLTEFKDKKLHSVTRGDLELGELEDAADKEAHDKVAEESKGLIERVKAALADSVSEVRVTSRLTDTPACVVAGEGEMSTQMIKLMQAAGQPVPESKPTFEINPTHPLVEHLNNETDEQLFADWANLLLQQALLSEKGSLADPSAFIKLTNQMLLASVK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALD2_MOUSE
Sequence: MATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACLLPETVNMEEYPYDAEY
What are the official names of this protein?
Aldose reductase-related protein 2, AR, Aldehyde reductase, Fibroblast growth factor-regulated protein, Protein FR-1.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_STRZJ
Sequence: MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSGLILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGTMDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVAAQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: CISD1_BOVIN
Sequence: MSMTSSVRVEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKSMVNPHIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPLCDGSHTKHNEETGDNVGPLIIKKKDT
What is the function of this protein?
L-cysteine transaminase that catalyzes the reversible transfer of the amino group from L-cysteine to the alpha-keto acid 2-oxoglutarate to respectively form 2-oxo-3-sulfanylpropanoate and L-glutamate (By similarity).  The catalytic cycle occurs in the presence of pyridoxal 5'-phosphate (PLP) cofactor that facilitates transamination by initially forming an internal aldimine with the epsilon-amino group of active site Lys-55 residue on the enzyme (PLP-enzyme aldimine), subsequently displaced by formation of an external aldimine with the substrate amino group (PLP-L-cysteine aldimine).  The external aldimine is further deprotonated to form a carbanion intermediate, which in the presence of 2-oxoglutarate regenerates PLP yielding final products 2-oxo-3-sulfanylpropanoate and L-glutamate.  The proton transfer in carbanion intermediate is suggested to be controlled by the active site lysine residue, whereas PLP stabilizes carbanion structure through electron delocalization, also known as the electron sink effect (By similarity).  Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity).  May be involved in iron-sulfur cluster shuttling and/or in redox reactions.  Can transfer the [2Fe-2S] cluster to an apo-acceptor protein only when in the oxidation state, likely serving as a redox sensor that regulates mitochondrial iron-sulfur cluster assembly and iron trafficking upon oxidative stress (By similarity).
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 1, Cysteine transaminase CISD1, MitoNEET.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type III membrane protein.
Protein: G6PI_CAMJD
Sequence: MKSLTHLSSYRALSTHFSIIKDLHMRVLFKEDENRGFRYFLQSGDLKLDYSKNRISDETLKLLFDLANECSLKNKIKAMFEGQKINNTENRAVLHTALRNKTNRSVKIDDMDIMPNVREVLAKMQKFSDSLRTGSWLGYTNQIITDVVNIGIGGSDLGALMVCKALKNYAHPRLHMHFVSNVDGTQLQDVLERVHPASTLFIVASKTFSTQETLTNAFTARKWFLKHALDEKHIAKHFVAVSTNKEAVKDFGIEPENMFEFWNWVGGRYSLWSAIGLAIMIYLGKENFSSLLEGAYLMDEHFYNEPFEKNMPVIMALIGIWYINFFDAGSHIIAPYDSVLRYFPKFIQQLDMESNGKQIRKNGKKVDYDTGPIIWGDTGINAQHAFFQLLHQGTHLSPIDLIASLNKKGNLPDHHEILLSNVFAQAEAFMRGKTLEEVQEEMAKKGLKEDQIQKLAPHRVFSGNRPSNILLLDEIHPRSIGSLVALYEHKIFVQGVIWDINSFDQWGVELGKELAKTILSELKGGKTQEHDSSTNHLIQIYKNFNSN
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_STAAS
Sequence: MPAVTYEHIKTCKQSGARLGIVHTPHGSFETPMFMPVGTKATVKTMSPEELRQIEAKIILGNTYHLWLQPGNDIIKHAGGLHKFMNWDGPILTDSGGFQVFSLSNLRKITEEGVEFRHHTNGSKLFLSPEKSMQIQNDLGSDIMMAFDECPPMPAEYDYVKKSIERTTRWAKRCLDAHQRPEDQALFGIIQGGEYEDLREQSAKDLVELDFPGYAIGGLSVGEPKPVMYKMVEHTEQFMPKDKPRYLMGVGSPDALIECSIRGMDMFDCVLPTRIARNGTCMTSQGRLVIKNAKFADDLRPLDENCDCYTCQNYSRAYIRHLIKAEETFGIRLTTIHNLHFLLKLMEDIRQAIREDRLLDFKEEFFEQYGLNVENPKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: CSPLY_ARATH
Sequence: MKMKRTASSNSEAQSYNESPHSPLRFHSPLSDAGDLPESRYVSPEGSPFKIENPKSIVAGNKLTQFSPLPSPIPPPPPQFPPPRRQRNARVPMNSSSDKSPSSMVVHNSWVREDGGQTTTRKAGAPINGEESTRTTVNRARGDDLVSLTALGFRITEVILCVISFSIMAADKTQGWSGDSYDRYKEYRYCLAVNVIAFVYSAFEACDAACYIAKESYMINCGFHDLFVFSMDQLLAYLLMSASSCAATRVDDWVSNWGKDEFTQMATASIAVSFLAFGAFAVSALISSYRLFTHASS
What are the official names of this protein?
CASP-like protein 4A2, AtCASPL4A2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTS_PSEA7
Sequence: MAEITAAMVKELRERTGLGMMECKKALTAAGGDIEKAIDDMRAAGAIKAAKKAGNIAAEGSIAVKIAADNKAAVIIEVNSQTDFLALQDDFKGFVAESLEKAFNEKLTDAAPLVEAREEARLALVAKTGENVNIRRLTRVEGDVVGAYLHGHRIGVVVNLKGGNPELAKDIAMHVAASNPQFLSASEVSEEAIAKEKEIFLALNADKIAGKPENIVENMVKGRISKFLAEASLVEQPFVKNPEVKVGDLAKQAGAEIVSFVRYEVGEGIEKAEVDFAAEVAAQVAATKQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG056_VACCP
Sequence: MLNRIQTLMKTANNYETIEVLRNYLRLYIILARNEEGHGILIYDDNIDSIMSMMNITRLEVIGLTTHCTKLRSSPPIPMSRLFMDEIDHESYYSPKTSDYPLIDIIRKRSHEQGDIALALERYGIENTDSISEINEWLSSKGLACYRFVKFNDYRKQMYRKFPRCTIVDSMIIGHIGHHYIWIKNLETYTRPEIDVLPFDIKYISRDELWARISSSLDQTHIKTIAVSVYGAITDNGPMPYMISTYPGNTFVNFNSVKNLILNFLDWIKDIMTSTRTIILVGYMSNLFDIPLLTVYWPNNCGWKIYNNTLISSDGARVIWMDAYKFSCGLSLQDYCYHWGSKPESRPFDLIKKSDAKRNSKSLVKESMASLKSLYEAFETQSGASEVLMSPCRTFSFSRTEDTFSTSVINRVFENTGTGTYHPINDIPSLFIESSICLDHIIVNNQESNKYRIKSVLDIISSKQYPARRPNYVKNGTKGKLYIALCKVTVPTNDHIPVVYHDDDNTTTFITVLTSVDIETAIRVGYSIVELGALQWDNNIPELKNGLLDSIKMIYDLNAVTTNNLLEQLIENINFNNSSIISLFYTFAISYCRAFIYSIMETIDPVYISQFSYKELYVSSSYKDINESMSQMVKL
What is the function of this protein?
Plays a role in intracellular enveloped virus (IEV) transport to the cell surface through microtubule transport.  Together with protein OPG064, forms a complex that interacts with host KLC2 (kinesin light chain isoform 2) to engage the kinesin-1 complex and thereby promote IEV trafficking.
What are the official names of this protein?
Protein OPG056, Protein F12, Protein F6.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG056 family.
Protein: MHP1_YEAST
Sequence: MDSKDTQKLLKEHRIPCIDVGWLVRPSASTSKSSRPGKSESKANSVAPDIQMDTARPPVFETSVDSSSSILSSNDKGRRHSVAASLLMDNQRANAGSTSVPTNIPPPRGRSKSVVETNLSNVEADSGHHHHHRHHHHTEDAPAPKKVGFFKSLFGHRKKDQEQQEKERERKERSPSPTHVDRGAAIRRERTATISAESPPPLQYNAPPSYNDTVVPLTRSKTESEVYYENHPQSYYHGRMRTYHSPEEGKVDGTSPADDHNYGGSRPDPRLMDFLRYYKSKDYKLAAFKEGNFIKSSASPTTKKNRRASFSLHNDKPQPAKSLAHQKFDAKGRPIPPHPDAPKLPSAFRKKHPSNASIVDTVDSNSDVSSSAQNNNQTPSSHKFGAFLRKVTSYGNNNNNSTNASSLSANVNNPDTSSTSLWSSSSMEFDPSKITTVPGLENIRPLKHVSFATNTYFNDPPQQICSKNPRKGEVEVKPNGSVVIHRLTPQERKKIMESTSLGVVVGGTGQLKLLNPEEDDANAKSKEEMAPQKQNEVEAHDEEDNNSQRRNIVMAAAEAAAEARAKEAPNELKRIVTNNEEEVTVSKTASHLTIDKPMISRRGASTSSLASMVSSDTNGTNADDEGEILPPPSLKIPHDIVYTRCCHLREILPIPATLKQLKKGSTDPIPILQLRNPRPSMVEIWSFSDFLSIAPVLCLSLDGVQLTVQMLRIILSSLVYKQHFQKLSLRNTPLDEEGWKVLCYFVSKAKSLHSIDLTMVPSIKTNVQKPSKSSLKSKILRMQCNLENRSDMNWDLLTASIALMGGLEEIVISGAKMNSAQFKNFILVACIATERLGLAYNGLSKSQCDDLAKWMVQSKVTGLDVGFNDLNGKLSSFTDAVLGKIQKANEKNVFKFLSLNGTNLRVNEHDTFENNEVLKLISVLCYLENLKFLDISNNPAIFPHCVPTLIDFLPVFVNLVRLHIDYNNLSSTSVVMLAEILPMCSRLNYFSMLGTELDLASSKALAEAVRKSSSLMTLDVDYVYMPENIKEKISLYALRNIQGELKRVNSDDKDIKDSQFSSLQDQLSLLLTEKADNSEHYNKMVENFMAKIALARIKISKVVHDLFDLKLNGQLNLEGKEALIRLCFIEASLERGCDLLKQRHNNTLKSPEAVSKSRKGGNQAQPNSESCQRMLLSSSILQNSDHIALMPFGSAIVEKSSPDAEDAVEFREGDDSNVNHEDVPANDQQFRDEVDIKNKYSIIKRELEHEKLVGGGDLPVDKEILNRAAQSLDSDQIKEFLLKNDVSTILGVIDELHSQGYHLHHIFKKQGNQEETAFRTKDEQQSSQSNDSSANASPTTDPISTGSNTSRTNDNAHIPPTDAPGFDKFMNNAEENAIDAAYDDVLDKIQDARNSSTK
What is the function of this protein?
Essential for the formation and/or stabilization of microtubules.  Binds to microtubules in vitro.
What are the official names of this protein?
MAP-homologous protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic microtubules and mitotic spindles.
Protein: NHAP2_YERPS
Sequence: MDAITINSLFLVGAVLVAASILLSSFSSRLGIPILVIFLAIGMLAGTDGLGGIAFDNYPAAYLVSNLALAVILLDGGMRTRASSFRVALWPALSLATFGVIITAGLTGLVAAWLFNLDIIQGLLIGAIIGSTDAAAVFSLLGGKGLNERVSATLEIESGSNDPMAVFLTVTLIAMIAAGETSLSWMFLVHLIQQFGLGIIIGLLGGGLLLLLINRMELANGLYPLLAVSGGILVFALATALNGSGILAVYLCGLLLGNRPIRNRAGILQTFDGLAWLSQIGMFLVLGLLLNPSDLLPIAIPALLLSLWMILFARPLSVFIGLLPFRSFNLRERVFISWVGLRGAVPVILAVFPMMAGLPNANLFFNVAFFVVLVSLLLQGTTLSFAARKAKLVVPPTLAPVSRIGLDIDMNNQWEQFIYQLSCDKWCIGATLRDLKMPQGTRIAALFRGKDLLHPTGSTRLKEGDILCVIGQEHDLPALGKLFSQSPNIQLDERFFGDFILDADAKLQDISQIYGLNLEPTVDKQQTLGQFVLYLFGGEPVIGDQIEWDGLTWTIAEMESDRVSRVGVKIVTDKA
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SUB2_NEOFI
Sequence: MSHEEDLIDYSDEELQTTDAAATTAAPAANGAQDKKGDLTVSGGRPDKKGSYVGIHSTGFRDFLLKGELLRAITDCGFEHPSEVQQVCIPTAILNVDVLCQAKSGLGKTAVFVLTTLHQLEPVPGECSVLVMCHTRELAYQIKNEYARFSKYLPDVKTAVFYGGTPIQKDIEVLSNKESYPNIVVGTPGRLNALVREKKLSLRNVKAFVLDECDKMLDQIDMRRDVQEIFRATPADKQVMMFSATLSQEIRPICKKFMRNPLEVYVDDDTKLTLHGLQQYYIKLSESEKNRKLNELLDSLEFNQVIIFVKSTLRANELDKLLRECNFPSIAVHSGVSQEERIKRYKEFKEFNKRICVATDVFGRGIDIERINLAINYDLPADADSYLHRVGRAGRFGTKGLSISFVSSEEDEKVLKEIEKRFEVALPEYPEGGVDSSTYMA
What is the function of this protein?
ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus.  SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly.  May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase sub2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOB_HELPH
Sequence: MQQAPVVLSTLDKLLNWGRSNSLWPLTYGLACCAIEMMATGGSRFDFDRFGTIFRASPRQSDVMIIAGTLTKKHAEFMRRLYDQMPEPKWVISMGSCANTGGMFNTYATVQGADRVVPVDIYLPGCAPRPETLQYALMVLQDKIRRSKAIKQDAPKRLV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KAD_BLOPB
Sequence: MIRIIFLGPPGSGKGTQAHLIANKYNIPNISTGTMLRQALTRSTHKSYELHKNIMHTGDLVNDEFMVQLISTRINQNDCRNGFLLDGFPRTILQAKSMKQCKIFVNYIIEFFASDSVIIDRIAGRRIHVGSGRTYHIKFNPPRNYGLDDITGEILTTRKDDHEEAIRKRLSNYYQHTEPVLDYYREESKYKKMKYFSVDGNRDISKIYKELINIISS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_ALBFT
Sequence: MNDLEFMDRAENLLKAVETSCDRINDQTLADIDSQRVGSMVTLVFSNKSQIVINLQKPLHEIWLAAKSGGYHYKFDNKQWLDTKGQGEFFANLSRCASEQAGCPLVLNS
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: MDH2_BURTA
Sequence: MNTEAKRIAVSGAAGQIAYSLLFRIAQGDLLGEDQPVILQLLDLPQAYGAVQGVVMELQDCAFPLLKEIQVATDPHAAFLNADYAFLVGSKPRTKGMERRDLLAENAAIFRTQGRALNEAASRDVKVLVVGNPANTNASILRRFAPDLPDDAISAMIRLDHNRAVSMLAQRCNVDVDSIADMVVWGNHSPTMFPDYRHARIGRRLVKDLINDENWYRESFIPKVAQRGTAIIEARGASSAASAANAAIDQMRDWIFGSDGRWVSMSVPSDGSYGIAPGLMFGVPVICDGGRYERVKDIGIDAFARQRIDLSVRELQEEADVVNRLFADR
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: WDR89_BOVIN
Sequence: MEKIEEQFANLNIVKRSSETKEPTYLLGIDTSKTVQTEKGSLVAVLCSNGSIRIHDKERLNVIREFRGYPGLNGVKFANSHDSVYSSCTDGTVKCWDARLASGKPVQLFKGYPSNIFISFDISSNDHVICAGTEKVDDDALLVFWDARINSQDLSTTKEPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDISADNEDDALVTTCNSVSSVSFIGWSGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNVPDVREVINVKEGILDYLIGGLYHEKTDKLFVVGGTNTGIIRIMNCMTSGLVHVTSLQGGHAATVRSFCWNMQDDSLLTGGEDAQLLLWKPGAVEKTFTKKDSMKIASSVHQRVRVHSNDSYKRRKKQ
What are the official names of this protein?
WD repeat-containing protein 89.
Protein: UL17_HCMVM
Sequence: MDHALFTHFVGRPRHCRLEMLILDEQVSKRSWDTTVYHRRRKHLPRRRAPCGPQRPAEIPKRRKKAAVLLFWHDLCWLFRRLFFPREDSEPLMSDPARSPEEEE
What are the official names of this protein?
Protein UL17.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 UL17 protein family.
Protein: RPOC1_CARPA
Sequence: MIDRYKHQQLRIGLVSPQQISAWANRILPNGEIVGEVTKPYTFHYKTNKPEKDGLFCERIFGPIKSGICACGNYRVIGDEKEDPKFCEQCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKRLPSYIANLLDKPLKELEGLVYCDFSFARPITKKPTFLRLRGSFEYEIQSWKYSIPLFFTTQGFDTFRNREISTGAGAIREQLADLDLQIIIDYSFLEWKELGEEGPTGNEWEDRKIGRRKDFLVRRMELAKHFIRTNIEPEWMVLCLLPVLPPELRPIIQIDGGKLMSSDINELYRRVIYRNNTLTDLLTTSRSTPGELVMCQEKLVQEAVDTLLDNGIRGQPMRDGHNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPREIAIELFQTFVIRGLIRQHLASNMGVAKSKIREKEPIIWEILQEVMQGHPVLLNRAPTLHRLGIQAFQPILVEGRAICLHPLVRKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSPAIGDPISVPTQDMLMGLYVLTSGTRRGICANRYNPCNRKNYQNERIDDNNYKYTKEPFFCNSYDAIGAYRQKRINLDSPLWLRWQLDQRVIASREAPIEVHYESLGTYHEIYGHYLIVRSVKKEILCIYIRTTVGHISLYREIEEAIQGFCRACSYDT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MURC_SOLUE
Sequence: MTDKPKQYVKEMFFRPQHLHFTGIGGIGMSGIAEVLLNLGYQISGSDVKLSPITERLAAMGARVFEGHAASNIAGARALVVSSAVDEQNPEVQEARRISIPVIPRGELLAELMRLKYGIAVAGSHGKTTTTSMAATILNYAGLDPTVVVGGRVGTMGGSNARVGHSDFLVVESDESDGSFLKLAPIIAVVTNVDREHLDHYPDLDAIRAAFLEFVNKVPFYGAVIVCLDDANVQGLLPEIRRRTITYGTTAQADMEAGDISCGPFASEFRLRYRTADLGRFRLHIPGRHNVLNAMAAIAVAMELEVKPDTIREALETFSGVDRRFQLRGQERGIAVVDDYGHHPTEIRATLDGARQCGFRRIHVLFQPHRYTRTFHLMDEFARSFHQADSLFVMDIYAASEKPIPGVTAESLVERIRQFGHRGVEYVGTLDRGVDALVAAASEGDLVLTLGAGSVYQAGEKVLERLRTEGKG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.