PharMolix/UniProtQA huggingface dataset:
Protein: RMD1_MOUSE
Sequence: MALSSRLWRRLPPLRVCQQTRTWGSRGRCGAWGVRACEVIGNTRPFKRGFLFSALSYLGFETYQIISQAAVVHATAKVEEILAQADYLYESGETEKLYQLLIQYKESEDGELLWRLARASRDIAQLSKTSEEEKKVLVYEALDYAKRALEKKESSSAAHKWYAICISDVGDYEGIKVKIANAYVIKEHFEKAIELNPKDATSIHLMGIWCYTFAEMPWYQRRIAKVLFANPPSSTYEEALRYFHKAEEVDPNFYSKNLLLLGKTYLKLNNKKLAAFWLVKAKGYPAHTEEDKQIQTEAAQLLTGL
What are the official names of this protein?
Regulator of microtubule dynamics protein 1, RMD-1, mRMD-1, Microtubule-associated protein, Protein FAM82B.
What is the protein family that this protein belongs to?
Belongs to the RMDN family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles.
Protein: ZFY21_BOVIN
Sequence: MSSEVAARRDAKKLVRSPSGLRMVPEHRAYGSPFGLEEPPWVPDKECPRCMQCDTKFDFLTRKHHCRRCGKCFCDKCCGQKVALRRMCFVDPVRQCAGCAPVSRREADFYDRQLKLLLSGATFLVTFENSEKPDTMVCRLSSNQRFLLLDGDGDGDGHREVEVARIAAVQMLTEGLPPGDTLSHTSLPASRPAAEGGNARAIGMTLQYTTPGAEGLTQLTLTAGEDADGSRRQATAWLAAMHKAAKLLYESRDQ
What is the function of this protein?
Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions.  Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta-1/ITGB1 cell surface expression (By similarity).
What are the official names of this protein?
Zinc finger FYVE domain-containing protein 21.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cytoplasmic vesicle. Endosome.
Protein: RL21_LACLM
Sequence: MSNYAIIKTGGKQVKVEEGSVIYVEKLNVEAGQTVTFDEVIFVGGETTKVGAPLVEGATVVGEVEKHGKQKKVVTFQYKPKKHSHRKQGHRQPYTKVVIKSVNA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ACCA_SYNPW
Sequence: MPRRPLLEFEKPLVELEQQIEQIRQRARDSEVDVSPQLHQLETLAARRREEIFKSLTPAQKIQVARHPHRPSTLDYIQMLCDDWVELHGDRRGSDDQALIGGIGRLGDRAVLLIGHQKGRDTKENVARNFGMATPGGYRKALRLMDHANRFGLPILSFIDTPGAYAGLLAEEQGQGEAIAVNLREMFRFRVPIIATVIGEGGSGGALGIGVADKLLMFEHSVYTVASPEACASILWRDAGKASEAASALKITGPDLLSLGVVDEVLPEPVGGNHWAPLEAGEILKEALTRNLEGLLQLSEDALREQRYRKFRAMGQFLDDLSPEALMAE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRRMC_MYCPN
Sequence: MKIRISLNILAKFLDSFAHLLFLKNKEIYTPRKEQAACVEVLERYFQANPENGRFLMNCKMRFGKCFTLYSYAQKNNINKILILTFVPAVEESLKDDLNHIEKNYKFYTDDDLQKSNFDLKNQNEPYVVFLSLQNVLGKQRIDGAKTDFDKERISKLQEIDFDLIVFDEYHYGANKKRTQIKVEKVNKKIDNPEQQDNQDDAEEELASTFKLKDIKSKFQFSYKQLVCLSGTPFSSLRNNEFSSKDQVFTYSYFDEQKAKSAENHPLKLGQYGIFPEMNIYCFELAEIFTAQEQEIFITPGKGKNKLPEISFRKLFQTENVSKESSKPVYRFVNENLVEKLIDSLIDKRKGFSHTPLSWENIDKHKHSLLILPTRVACFALANLLKNHWYFENNDFQIINMSESQFGNGKKALIELNKHLDEAKKTNKNTLTITVAKLTIGITVKEWSTVFFLKDLKGAESYFQTIFRIQTPYIKNCKNLKEICYVYDFNMYRCLEVTNEYSKQTQTDPKFSASWFQNLDKFLPIYLVRGDEIQKTDPEILQKYEYFIMDKRAFSTRWMDESNIIDIDVLCNVGQDEDAQKILKKILAHKKFKSSKKKREFEDVHLEKSPKSEAFSEGVRSGKDYAAEQGNVLEELENFWNFNQALEQKAKAEFQQKNFDDNEWNNYKKGFNFGVNKHFEDKVSIKKIVQNKIKDFKKRKGRTTSTFKKWKWLYFWWE
What is the function of this protein?
Corresponds to the C-terminus of a putative G subtype type II restriction/methylase subunit.
What are the official names of this protein?
Putative type II restriction enzyme and methyltransferase RM.MpnORF110P C-terminus.
Protein: GDPP1_HUMAN
Sequence: MALPHDSNETSYLLPPNNEDWGRQTIPDFVYGQKDLMAEGIQWPRNAPGIPDALPQSPFDAALCSAWKQRVELGLFRYRLRELQTQILPGAVGFVAQLNVERGVQRRPPQTIKSVRQAFDPVQFNFNKIRPGEVLFRLHREPDLPGTLLQEDILVVINVSPLEWGHVLLVPEPARQLPQRLLPGALRAGIEAVLLSLHPGFRVGFNSLGGLASVNHLHLHGYYLAHRLPVEQAPSEPLDPGGHLHLLQDLPAPGFLFYTRGPGPDLESLISRVCRATDYLTDHEIAHNLFVTRGAPPGKTSPSSALTGVRVILWARKSSFGIKDGEAFNVALCELAGHLPVKTSQDFSSLTEAAAVALIQDCRLPPSQAEDVQAALVALMSQEEQ
What is the function of this protein?
Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
What are the official names of this protein?
GDP-D-glucose phosphorylase 1.
What is the protein family that this protein belongs to?
Belongs to the GDPGP1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_BARBK
Sequence: MTLALRYKRVLLKVSGEALMGEQSFGIDVSVADRIASDIAEVRKMGVEVAIVIGGGNIFRGVAVASHGGDRVTGDHMGMLATAINSLALRTSLTKLGVETVVLSAITMPQICESFSQRKAMSYMNQGKVVIFAGGTGNPFFTTDSAATLRAAEIGADVLLKGTQVDGIYSADPKINSTAKRFDQLTHVEILRLGLSIMDTTAVTLARENNIPIIVYSIHEKGGLTKVLNGTGRFTVVSE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_ACIB3
Sequence: MKVQVKLLDPRLGKEWPLPSYATAGSAGLDLRACLDEAIEIEPGQTVLVKTGMAIYIHDVNFAGLILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSVWNRGQTTFRLEPGERLAQYVLVPVVQAEFEQVEEFEETLRGAGGFGHTGKQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: ACCD_EUCGG
Sequence: MEKWWFNSMLYKGKLEYRCGLSKSIDRFGNPIEKTSVSEDPVRNDTDKKIHSWSESSSYSNATHFVGVRDVRNFISDDTFLVRDSNRNIYSIYFDITNQIFEIDNDPSLLSERESSFFSYRTYAYLKNGSKNDDPPCDRSMYDTKYSWNNHITSCINSYLGSQICIESSILSSSDNSSDSYISSYIYGESRNSNERGSSSIRTSRNGIDFTRRENSTDFDLTQKYRHLWVQCENCYGLNYKKLLKSKMNICDQCGYHLKMSSSDRIELSIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRIDSYQRKTGLTDAVQTGTGRLNGIPIAIGVMDFQFMGGSMGSVVGEKITRLIEYATNQFLPLILVCASGGARMQEGSLSLMQMAKISAALYDYQSHKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKIVPEGSQAAEYLFHKGLFDPIVPRNPLKGVLSELFKLHAFFPLN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: UVRA_CLOAB
Sequence: MKDKIVIKGAKVHNLKNVDLTVPRNEFVVFTGLSGSGKSSLAFDTLYAEGQRRYMESLSSYARQFLGQMDKPNVEYIEGLSPAISIDQKTTGRNPRSTVGTVTEIYDYLRLLYAKIGVPHCPNCGKEISQQTVDQIVDSVMKLEERTKIQVLAPVVRGRKGEHTKLIAHIKKSGFVRVRIDGEVYEIDEDEIKLDKNKKHHIEALVDRIVIKQGVEGRLTDSVETALKLAEGLVVINVMGKEDMLFSENFACPDCGISIGEISPSMFSFNAPFGKCDVCDGIGTLLEIDEDLVIPDKSKSIMEGAIAPWGEGRLKEESWTFGVLKALSKKYKLDINKPIEDYDEKTLNILLYGAPDVLKVNYVKDSQEMVFNHHYEGIINQMKRRYMESNSDYIKSEIENYMSNNPCPKCKGARLKKEVLAITVGNKNIFEFCSMPIREEVSFIDTLELSNKHKIISAQIVKEIKSRLEFLINVGLDYLNLAREARTLSGGESQRIRLATQIGSSLVGVLYILDEPSIGLHQRDNDRLIATMKNLKDIGNTLIVVEHDEDTIKAADFIVDIGPGAGEHGGEIIAAGSLEDIKNCKESITGQYLTGVKKIEVPKERREAGKNFIEIVGAKENNLKNVNVKFPVGLFTCVTGVSGSGKSTLVNEILYKALNKKINRSKLNPGKYKSINGIENIDKIIDINQSPIGRTPRSNPATYTGVFDIIRELYASTKEAKLRGYKAGRFSFNVKGGRCEACKGDGIVRIEMQFLSDVYVPCDVCKGKRYNRETLEIKYKDKNIDDLLNMTVEDALKFFENLPRIKNKLQTLADVGLGYVRLGQPSTQLSGGEAQRIKLAYELSKRSTGKTLYILDEPTTGLHTDDVKKLISILQRLTDMGNTVVVIEHNLDVIKCADYIVDLGPEGGEKGGTILCSGTPEQVAQNSSSYTGQYLKKML
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VANH_ENTFA
Sequence: MRKSMGITVFGCEQDEANAFRTLSPDFHIIPTLISDAISADNAKLAAGNQCISVGHKSEVSEATILALRKVGVKYISTRSIGCNHIDTTAAERMGISVGTVAYSPDSVADYALMLMLMAIRGAKSTIHAVAQQNFRLDCVRGKELRDMTVGVIGTGHIGQAVVKRLRGFGCRVLAYDNSRKIEADYVQLDELLKNSDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDTGSLVEALGSGKLGGAALDVLEGEDQFVYTDCSQKVLDHPFLSQLLRMPNVIITPHTAYYTERVLRDTTEKTIRNCLNFERSLQHE
What is the function of this protein?
Required for high-level resistance to glycopeptides antibiotics.  Catalyzes the reduction of 2-keto acids to 2-D-hydroxy acids that give rise to peptidoglycan precursors that terminate in the depsipeptide D-alanine-2-lactate rather than the dipeptide D-alanine-D-alanine thus preventing vancomycin binding.
What are the official names of this protein?
D-specific alpha-keto acid dehydrogenase, Vancomycin B-type resistance protein VanHB.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: SYFB_THEGJ
Sequence: MPKFDVSKRDLERLVGKEFTVEEWEDLFLYAKCELDDVWEENGEIYFKADSKDTNRPDLWSAEGIARQIRWALGFRRGLPEYEVEKSDVTVYVDEKLKDIRPYGVYAIVECLKLDEEALKQMINLQEKVALTFGRRRREVAIGIFDFDKVKPPIYYRAAEKTEKFVPLGFEEELTLEEILEKHEKGREYGHLIKDKPYYPLLVDSEGKVLSMPPIINSETTGRVTTETRNVFVDVTGWDLNKVMLALNVVVTALAERGGRIKSVKVVYPDFEIETPNLTPKSFEVELDYIRKLAGLDLSDGEIKDLLERMMYDVTLEDGKAKLLYPAFRDDIMHARDVLEDVLIAYGYNEIEPEEPKLAVQGRGDKFIEFEDAVRELMVGFGLQEVMTFNLTNREAQYGKMNLEYGRDYFNNPPAELVEIENPISPKWSALRNWLLPSLLDFLSQNTHEEYPQRLFEVGKATLIDESRETKTVSESKLAVVLAQPRVTFTDTKEILDSVMRHLGFEYELEEVEHPSFIPGRVGKVIVKGKAIGVIGEIHPSVLEKWGIEMPVAGFELFLRPLYTEPYL
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2_CHLVU
Sequence: MLQKVKLEDMIQSGMHFGHSTREWNPRMAPYIYGERNGRHILDLVQTYYLLNKVLAFLEEQAAQGKTFLFVGTKQQAAPLIAKTALACESFYVNQRWLGGMLTNWRTIQKSLRKLQEYRRAEERGDWNLLKKQEVARKRREKDRLEKYLSGVENMSRLPGVVILIGQTEEIHAVKECRQLGIPTVTLLDSNCDPNLADWFLPANDDSVSALRLILAWFQQAIQTGQLRSLEREAAKKQKIKKTGVKISGNRRTSSITKKRNPASSKI
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL17_BURCJ
Sequence: MRHRHGLRKLNRTSSHRLAMLRNMSNSLIEHEVIKTTLPKAKELRKVVEPLITLGKKPSLANRRLAFNRLRDRDSVAKLFDVLGPRFANRPGGYLRVLKFGFRVGDNAPMALVELLDRPEVDETENVQEAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: QUEA_SHEB9
Sequence: MRVADFSFDLPDELIARYPMAQRNASRLLTLDGNSGALGDKQFTDLLGMINPGDLMVFNNTRVIPARMFGQKASGGKLEILVERMLDDKRILAHVRSSKSPKVDSLILLDGGYQMKMVARHDTLFELELLSELTILEVLEAVGHMPLPPYIDRPDEDADKERYQTVYNQNPGAVAAPTAGLHFDDAMLDALKAKGVNIAFVTLHVGAGTFQPVRVDTILEHKMHSEWANVPQDVVDLIAQTKAAGKRVVAVGTTSVRSLESAARASQGELKAFSGDTDIFIYPGYQFQVVDAMVTNFHLPESTLIMLVSAFAGFDHVMAAYQHAIAQKYRFFSYGDAMFVTKKAH
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_NAUPA
Sequence: MLIDKFERKIDYIRVSVTSRCNFRCLYCMPNTPFEWEPHENILRYEEMFEFLRLAIDEGINKIRLTGGEPLLRKDLDVFVKMLHDYRPDLDLALTTNGYYLKEYAKKLKDAGLKRVNMSLDSLKPEVAAKIAQKDVLNRVIQGLDEALKVGLKVKLNTVVMQGINDTEILDLLEFAKNKGVTIRFIEFMENERAYPGVKRVDSKVILDKIAKKYKFKELPKDNSASRYFETEDGYVFGIIEPHNEDFCKSCNRIRLTAEGYLIPCLFFTESYNIKEALREGNIQKASEILREVVANKPEKNDWQDEEVSTRAFWETGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: ATPF_MESFL
Sequence: MIFFAETQTAGVPEIITSLFPNLPNFIAHVIATIVLVVILSKLMYKPFRKTIKDRRNKINELLSEAVQKQTEANIGVRKAEALLQDAKTESSLIIQTSKVDADIQKTHIISEAHKYADIIKNQAEKDIAQERSKIEAEIKTTIVNVAFDAAEQILQTEINKTKNKKIVDEFIENLDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SSN3_YARLI
Sequence: MSNYRRGVGSYSRMLGGGTNPFAAYTARKAKTKKRVLDKYEIIGYIAAGTYGRVYKARSKDPGDTNQYAIKKFKADKEGEMVHYAGISQSACREVALCAELDNRNITKLVETILEDTCIYMVFEYAEHDLLQIIHYHSHPERKPIPEYTLKSILWQLLNGVSYLHQNWVLHRDLKPANTMVTSDGVLKIGDLGLARLFSNPLQSLYSGDKVVVTIWYRAPELLLGARHYSPAVDLWAVGCIFAELLALRPIFKGEEAKMDNKTNVPFQRNQMQKIIEILGSPQEDDWPSLSKFPEYESLKQMKTFPPNLEAWYQSIGGTNQKGFQLLSRLLEYDPAKRLTANDALLHPYFTEAPKVSQNVFERQEYKYPPRRISCEDSDIKTMTYQGTKRGSQGGDNLHPRKKQK
What is the function of this protein?
Component of the srb8-11 complex.  The srb8-11 complex is a regulatory module of the Mediator complex which is itself dependent transcription.  The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase SSN3, Cyclin-dependent kinase 8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS17_PROM2
Sequence: MALKERIGTVVSDKMDKTVVVAVINRYPHPTYKKIVSRTTRYKAHDPENTCVTGDRVKIRETRPLSAQKRWAIEEILNKTNQAKEVKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DDL_BORGP
Sequence: MKKNLMLIFGGVSFEHEISCKSAYSIYLALLDLNKYNIYPVYIDKCTGIWYLLDSVSDPPKLIDIDVLPIVSLLPGIGIFSNNKNLDIDVVFPVVHGRTGEDGAIQGVLKVMDIPCIGAGIIGSAISSNKYFCKLLLKSFNIPLVPFIGFRQYDYFLDKEEVKRNVREALGYPVIVKPAVLGSSIGINVAYSENQIEFFIEEALKYDLTILIEKFIEAREIECSIIGNEKIKIFSPGEVIVQDFIFYDYDAKYSVIPGNSIIFNIPAQLETNQLLSIKEYAFLVYKNLELRGMARVDFFVEKKSGKIYLNEINTIPGFTDISMFAKMCSHDGLQFKDLVDNLINYAFQSYINRKKRINFED
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_MARMS
Sequence: MALGLEDKKAIVAEVSEVAKTALSAVVADSRGVTVSSMTELRKEAREAGVYVRVVRNTLARRAVEGTDFECLAESFVGPTLIAFSNEHPGAAARLLKAFAKTNSKFEVKALAFNGELIPAGDIDRLATLPTYDEAIAKLMSVIQGATSKFVRTLAAVRDQKEQEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PGDA_LISMO
Sequence: MKIRWIRLSLVAILIIAVVFIGVIGFQKYQFSKSRNKVIMQMDRLMKDQDGGNFRRLDKKENGVEIISYIPKTTEKKDNEIIQKEIGKATDAEVKKLNRDKETQGIIFYTYQKHRMAEQAISYKAVQSEYVKEGRTKFVLKDKKDICKNIVTDAETGALLTLGEVLIKSNQTKLNLKTAVEEELIKTGDFSLKDVGNLGKIKSLVKWNQTDFEITNSEIILPVKIPGAPEPKKVKVKLADIASSVNKRYLPSSVKVPEVPKAKTNKRIALTFDDGPSSSVTPGVLDTLKRHNVKATFFVLGSSVIQNPGLVKRELEEGHQVGSHSWDHPQLTKQSTQEVYNQILKTQKAVFDQTGYFPTTMRPPYGAVNKQVAEEIGLPIIQWSVDTEDWKYRNAGIVTKKVLAGATDGAIVLMHDIHKTTAASLDTTLTKLKSQGYEFVTIDELYGEKLQIGKQYFDKTDSRMVK
What is the function of this protein?
Catalyzes the deacetylation of N-acetylglucosamine (GlcNAc) residues in peptidoglycan (PG) (By similarity).  Deacetylates also N-acetylated PG (PubMed:17215377).  Does not deacetylate N-acetylmuramic acid (By similarity).  Confers host lysozyme resistance (PubMed:17215377, PubMed:29215169).  Critical for virulence and escape from innate immune response of the host.  Required for intracellular survival of bacteria in macrophages of the host (PubMed:17215377).  Required for successful host colonization (PubMed:17215377, PubMed:21844299).  Controls the production of inflammatory mediators in the bone marrow derived macrophages (BMMs) of the infected mouse (By similarity).  Suppresses Toll-like receptor 2 (TLR2)-dependent secretion of interleukin 6 (IL-6) and interferon-beta (IFN-beta) in the macrophages of the infected mouse.  May decrease accessibility of pattern recognition receptors (PRRs) such as nucleotide-binding oligomerization domain protein (NOD) 1 of the host to the bacterial cell wall components (PubMed:17215377).  Protects cells from autolysis induced by lysozyme or by other autolysis-inducing agents (By similarity).
What are the official names of this protein?
Peptidoglycan-N-acetylglucosamine deacetylase PgdA, Peptidoglycan GlcNAc deacetylase, Peptidoglycan N-deacetylase, PG N-deacetylase, Petptidoglycan deacetylase, PG deacetylase.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein; Extracellular side. Secreted, cell wall.
Protein: MOAA_STRCO
Sequence: MLRRSASREGAHVLIDTYGRVATDLRVSLTDRCNLRCTYCMPEEGLQWLAKPDLLTDDEIVRLIDIAVTSLGIEEVRFTGGEPLLRPGLVGIVERVAALEPRPQMSLTTNGIGLRRTATALKAAGLDRVNVSLDTLRPDVFKTLTRRDRHKDVLEGLAAAREAGLTPVKVNSVLMPGLNDDEAPDLLAWAVEHDYELRFIEQMPLDAQHGWKREGMVTAGDILTSLRTRFELTAEGSEERGSAPAERWLVDGGPHRVGVIASVTRPFCSACDRTRLTADGQVRTCLFATEETDLRAALRSDAPDEEIARIWRLAMWGKKAGAGLDDPTFVQPDRPMSAIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: GPMA_BACC4
Sequence: MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDMAYTSVLKRAIRTLWIVLHEMDLTWVPIHKSWKLNERHYGALQGLNKDETAQKYGEEQVHIWRRSVDVRPPALTEDDPRYEATDPRYKTLKKGEFPLTECLEDTEKRVLAYWHSEIAPTLKSGNKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIPKHISF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: HCNC_PSEAE
Sequence: MNRTYDIVIAGGGVIGASCAYQLSRRGNLRIAVVDDKRPGNATRASAGGLWAIGESVGLGCGVIFFRMMSSRNRREAQGAAVAVDASTPHILPPAFFDLALQSNALYPELHRELIERHGMDFKFERTGLKYVIQDDEDRQYAEHIVAQIPHLAEQVRWLDREELRRAEPAVSHAAHGALEFLCDHQVSPFRLADAYLEAARQNGVELLPGTNVTGVLRQGRRISGVRTDNAGVLHCRTLINAAGAWAAELSEMATGRRIPVKPVKGQIVLTERMPRLLNGCLTTSDCYMAQKDNGEILIGSTTEDKGFDVSNTFPEIAGLVQGAVRCVPELQQVNLKRTWAGLRPGSPDELPILGPVAEVEGYLNACGHFRTGILTSAITGVLLDRLVHEETLPLDIAPFLAARFQPEPAAVAVAAC
What is the function of this protein?
A three-component membrane-bound flavoenzyme that catalyzes the formation of hydrogen cyanide, a secondary metabolite, by transfer of electrons to a cyanide-resistant branch of the aerobic respiratory chain.
What are the official names of this protein?
Hydrogen cyanide synthase subunit HcnC, HcnC, Glycine dehydrogenase (cyanide-forming).
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cell membrane. Cell membrane; Single-pass membrane protein. Cell membrane; Lipid-anchor.
Protein: MRAY_BORBZ
Sequence: MFYLLGLRLLKYITFRMAYATIFAFLLSLIVGPYIILKLKKLRADQILREDGPKRHLSEKAGIPTMGGILIFFCVFISLVFWSNILNVYFLIMVFVMLGFAFLGFIDDFLKIKKKTSDGLKARFKIYGQIIFSFFSVGILYYFGGEHVSVIYFPFIKSFQIDLGLFYIPFGMFILISASNSFNLTDGLDGLAIGLSIVITGALIIIAYLTSRADFAAYLHIPNIKGSEELVIFLGALLGGSFGFLWFNAYPAKIMMGDTGSLALGAILGMAALILKSEILFSILAGVFIIETMSVIIQVLVYKKTKKRVFKMAPLHHHFEELGWSEMQVVIRFWIIGLIFAIIALSTIKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS8_SULDN
Sequence: MKFNKHLQNIKTYEAGKPIELVVREYGIEPQDIVKLASNENPLGCSPKVIDAVGKILTKMSLYPDDSMISLKNALSKRYNVDSENVIIGSGSDQVIEFLIHAKAHSGSKILMNSITFAMYEIYSKHVGADVIRTSSQEHDLDEFYELYKQEKPEIIFICTPNNPTGDALDAQKIYNFLEKIDNDTLVVVDAAYMEYAIVKDAKKEINVKELIQKHSNVIYLGTFSKAYGLGGMRVGYGISEAKIIKELYKLRPPFNITTLSLEAATVALSDEEFVQKSTALNLEQMKRYEEFAKEQKIDIINSYTNFVTLSLGSNQNSTKIASQLLQNGMIVRDLSSYNMNAIRVTIGTQEQNSRFFKLVIKFL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: AIM11_YARLI
Sequence: MKFRFGEGAEGTLNTSVTTAMIDQEKRAADLKRRKNQMLLFGGATLATLASCRLTARGISSRRYIPKMFQANHMPPQSDMVKEAAMAVVFATTMALSSFSMVVFGVAWSQDVTSLKQFALKMKTKLGAQQIEDEIRNAPMTPETQDLQDQLAGALKKD
What are the official names of this protein?
Altered inheritance of mitochondria protein 11.
What is the protein family that this protein belongs to?
Belongs to the AIM11 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.