PharMolix/UniProtQA huggingface dataset:
Protein: NUOE_BUCAP
Sequence: MDKKKKIKEISTTFTLTTFEINEIEKQKKYYENSRSVSIEALKIVQKKRGWVCDQAIIEIANILNLNPSEVESVATFYSQIYRQPVGRNVIRYCDSVVCYLTGYEKIKKFLEDYLFIKIGNTTVDGRFTLLPVCCLGNCDKAPTIMINEDLYSHLNPDLIPNLLELYK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit E, NADH dehydrogenase I subunit E, NDH-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the complex I 24 kDa subunit family.
Protein: NIA_LOTTE
Sequence: KGPLGHIEYTGKGNFIAHGEPKFARRLAMLAGGTGITPIYQVIQAVLKDPDDRTEMFFAVYSNKTESDILLREELDAWAKKHSDRFKVWYVVDKAGNDWAFSTGRVNESIMRVHLPGPSDALALACGPPPINSAYGWQPSLENIGYKKDDVPVFMATTQS
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADH], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: DNA2_YEAST
Sequence: MPGTPQKNKRSASISVSPAKKTEEKEIIQNDSKAILSKQTKRKKKYAFAPINNLNGKNTKVSNASVLKSIAVSQVRNTSRTKDINKAVSKSVKQLPNSQVKPKREMSNLSRHHDFTQDEDGPMEEVIWKYSPLQRDMSDKTTSAAEYSDDYEDVQNPSSTPIVPNRLKTVLSFTNIQVPNADVNQLIQENGNEQVRPKPAEISTRESLRNIDDILDDIEGDLTIKPTITKFSDLPSSPIKAPNVEKKAEVNAEEVDKMDSTGDSNDGDDSLIDILTQKYVEKRKSESQITIQGNTNQKSGAQESCGKNDNTKSRGEIEDHENVDNQAKTGNAFYENEEDSNCQRIKKNEKIEYNSSDEFSDDSLIELLNETQTQVEPNTIEQDLDKVEKMVSDDLRIATDSTLSAYALRAKSGAPRDGVVRLVIVSLRSVELPKIGTQKILECIDGKGEQSSVVVRHPWVYLEFEVGDVIHIIEGKNIENKRLLSDDKNPKTQLANDNLLVLNPDVLFSATSVGSSVGCLRRSILQMQFQDPRGEPSLVMTLGNIVHELLQDSIKYKLSHNKISMEIIIQKLDSLLETYSFSIIICNEEIQYVKELVMKEHAENILYFVNKFVSKSNYGCYTSISGTRRTQPISISNVIDIEENIWSPIYGLKGFLDATVEANVENNKKHIVPLEVKTGKSRSVSYEVQGLIYTLLLNDRYEIPIEFFLLYFTRDKNMTKFPSVLHSIKHILMSRNRMSMNFKHQLQEVFGQAQSRFELPPLLRDSSCDSCFIKESCMVLNKLLEDGTPEESGLVEGEFEILTNHLSQNLANYKEFFTKYNDLITKEESSITCVNKELFLLDGSTRESRSGRCLSGLVVSEVVEHEKTEGAYIYCFSRRRNDNNSQSMLSSQIAANDFVIISDEEGHFCLCQGRVQFINPAKIGISVKRKLLNNRLLDKEKGVTTIQSVVESELEQSSLIATQNLVTYRIDKNDIQQSLSLARFNLLSLFLPAVSPGVDIVDERSKLCRKTKRSDGGNEILRSLLVDNRAPKFRDANDDPVIPYKLSKDTTLNLNQKEAIDKVMRAEDYALILGMPGTGKTTVIAEIIKILVSEGKRVLLTSYTHSAVDNILIKLRNTNISIMRLGMKHKVHPDTQKYVPNYASVKSYNDYLSKINSTSVVATTCLGINDILFTLNEKDFDYVILDEASQISMPVALGPLRYGNRFIMVGDHYQLPPLVKNDAARLGGLEESLFKTFCEKHPESVAELTLQYRMCGDIVTLSNFLIYDNKLKCGNNEVFAQSLELPMPEALSRYRNESANSKQWLEDILEPTRKVVFLNYDNCPDIIEQSEKDNITNHGEAELTLQCVEGMLLSGVPCEDIGVMTLYRAQLRLLKKIFNKNVYDGLEILTADQFQGRDKKCIIISMVRRNSQLNGGALLKELRRVNVAMTRAKSKLIIIGSKSTIGSVPEIKSFVNLLEERNWVYTMCKDALYKYKFPDRSNAIDEARKGCGKRTGAKPITSKSKFVSDKPIIKEILQEYES
What is the function of this protein?
Key enzyme involved in DNA replication and DNA repair.  Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1.  Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.  Possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase, 5'-3' helicase and endonuclease activities.  While the ATPase and endonuclease activities are well-defined and play a key role in Okazaki fragments processing and DSB repair, the 5'-3' DNA helicase activity is atypical: it cannot load onto its tracking strand internally and has an absolute free 5'-end requirement.  Helicase activity may promote the motion of DNA2 on the flap, helping the nuclease function.
What are the official names of this protein?
DNA replication ATP-dependent helicase/nuclease DNA2.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Recruited to double- strand. break (DSB) sites following phosphorylation at Ser-17 and Ser- 237.
Protein: RS17_MYCMS
Sequence: MQRNSRRVLIGKVVSDKMDKTITVLVETYKNHPIYKKRVKYSKKYKAHDENQVAQMGDKVEIMETRPLSKTKNFRLVRVIEKATL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: VATA_HYPBU
Sequence: MPVKGRIIRVAGPLVVAEGMEGIQMYEMVEVGEERLIGEVNRVVGDKAYIQVYESTTGLKPGEPVYGTGSPLSVELGPGLIGRIYDGIQRPLDVIREVTKSIFVRRGVKVDALDRSRKWHFKPNTTLKPGDKVSGGDVLGEVQETSLITHKVLVPPDVHGRLKWLASEGDYTVEDVIAVVEADGKEIELKMYHRWPVRRARPIIEKLEPVEPLITGMRVIDTMFPMAKGGTGAIPGPFGSGKTVTLQSLAKWSAAKVVIYIGCGERGNEMTEVLETFPKLTDPWTGKPMMERTILIANTSNMPVAAREASIYTGITLAEYYRDMGYDVLLVADSTSRWAEALREIAGRLEEMPAEEGYPSYLASRLAEFYARAGRVKVPGRPERLGSVTIVGAVSPPGGDFTEPVTANTKRFIRVFWALDARLAYSRHYPAINWLVSYSAYVETVAKWWHENISPKWLEYRNEAYEILLREDELREIVRLVGTEGLSEKDKLILEIANIIKTGFLQQNAFDPVDAFATPQKQWKQLETIIDFYHAALEAIKRGVTVKEIREKLAPKIRELILARYNVPNDQLEKLDKLKQELLQALQELIEAKAGRASAAT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: YQFG_ECOLI
Sequence: MNFLMRAIFSLLLLFTLSIPVISDCVAMAIESRFKYMMLLF
What are the official names of this protein?
Uncharacterized protein YqfG.
Protein: RECX_SALPK
Sequence: MSEPTSRRPAYARLLDRAVRILAVRDHSEQELRRKLSAPVMGKNGPEEIDATADDYERVIAWFHEHHYLDDERFVMRFIASRSRKGYGPARIRQELNQKGISRESTEKAMRECEIDWSEMAREQAVRKYGEPLPSNFSEKVKVQRFLLYRGYLMDDIQQIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S22AO_HORSE
Sequence: MAFQDLLDQVGSLGRFQILQTAFFCICILIAYPHMLLENFTAAVPGHRCWVHILDNDTVSANGTEILSQETLLRISIPLDSNLRPEKCRRFIHPQWQFLDLNGTFPNMSEPDTEPCVDGWVYDRSSFSSTIVTEWDLVCESQSLISVAQSLFMVAQLLGGLIFGHISDRFGRKIIFRCCLLLFAISGTCAAIAPTFPVYCSLRFLGGICLMNIITNAVSTMSEWTGPKSIALMTGIILNSCNIGQILMGGLGFVIQDWRTLQLTMSIPLFILFLFSRSVLESAQWLIITNQLDEALKELRRAAHINGKKDTGETLTIEFVKSTMKQELDEGQTNVSLFDLLRPPKLRVRIFYLSFVRFAATIPFLGLMLNLQHFGSNIFLFQIIFGAVTFIVRCAVLLTMNHVGRRISQMVSSFLVGIPILVNIFLSQEMQTLRVALATLGIGATTAIFTTHTVHHNELVPTVLRSIAIGLNAMFSRLGATLAPLLMILTVYSPDLPWIIYGVSSILAGLVVLLLPETRNQPLPNTIQDVENNRRDSRKTKQEDISMKVTQF
What is the function of this protein?
Renal transmembrane organic anion/dicarboxylate exchanger that participates in the reabsorption of conjugated steroids, as well as bile acids, driven by an outward gradient of dicarboxylates such as glutarate or succinate (By similarity).  Transports taurocholate, estrone 3-sulfate, and estradiol-17-glucuronide (17beta-estradiol 17-O-(beta-D-glucuronate)), but not androstanediol glucuronide (5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)) (PubMed:31553721).
What are the official names of this protein?
Steroid transmembrane transporter SLC22A24, Solute carrier family 22 member 24.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Protein: CITE4_HUMAN
Sequence: MADHLMLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHALGGMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSAPPAGSVSC
What is the function of this protein?
Acts as transcriptional coactivator for TFAP2/AP-2.  Enhances estrogen-dependent transactivation mediated by estrogen receptors.  May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP.  May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells.
What are the official names of this protein?
Cbp/p300-interacting transactivator 4, MSG1-related protein 2, MRG-2.
What is the protein family that this protein belongs to?
Belongs to the CITED family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TX1A_GRAIH
Sequence: SCQKWMWTCDQKRPCCEDMVCKLWCKIIK
What is the function of this protein?
Inhibits mammalian and insect voltage-gated sodium and potassium voltage-gated channels.  Inhibits the mammalian sodium channels rNav1. 2/SCN2A, rNav1. 3/SCN3A, rNav1. 4/SCN4A, hNav1. 5/SCN5A, mNav1. 6/SCN8A (IC(50)=156. 39 nM), hNav1. 8/SCN10A, the arachnid sodium channel VdNav (IC(50)=124. 05 nM), as well as the potassium channels Kv11. 1/KCNH2/ERG1 (IC(50)=3. 7 uM) and rKv4. 3/KCND3.  In vivo, is lethal on insects (tested on flies M. domestica).  When tested on mice, it shows very low toxicity, causing reversible paralyzes at the first hour after intracerebroventricular injection.
What are the official names of this protein?
Beta/kappa-theraphotoxin-Gi1a, Beta/kappa-TRTX-Gi1a, GiTx1.
What is the protein family that this protein belongs to?
Belongs to the phrixotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_STRS2
Sequence: MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIVIDGTKYKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKEINYLHDSGVTTDNLRISDRAHVILPYHIKLDQLQEESKGENKIGTTNKGIGPAYMDKAARVGIRIADLLDKEIFAERLRTNLAEKNRLFEKMYESTPIEFDEIFEEYYAYGQEIKKYVTDTSVILNDALDQGKRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGPFPTELHDEIGDRIREIGKEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLSGLGTLKICVAYDLDGERIDHYPASLEQLKRCKPIYEEMPGWSEDITGVRSLDELPEAARNYVRRISELVGVRISTFSVGPGREQTNILESVWSAK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFR1_XENLA
Sequence: MESTSPHQGSFYKSNLCSPDSPKDTVPKQPMSATLRERLRKTRRSFNAAFSVAKRLKVDCEENESSSDCPNNNLPPHEDSEPNATKIEVDLVSEGDICRLDSRTSSEASSPVRCKDHKQLLQEKKLLLKKLEEQEDTLRRLKMVKLYRAKNNLSELQSLIEKWRKSSQLSLYELQAALIAENNKVTLSQLIESYGLDENLLHYNRTEEDFQDQ
What is the function of this protein?
Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination (By similarity).
What are the official names of this protein?
Swi5-dependent recombination DNA repair protein 1 homolog, Meiosis protein 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the SFR1/MEI5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPF_MANES
Sequence: MKNITDSFVSLGHWPSAGSFGFNTDILATNLINLSVVLGVLIFFGKGVLSDLLDNRKQRILDTIRNSEKLREGAIEQLEKARARLRKVEIEADQFRTNGYSEIEREKLNLINSTYKTLEQLENYKNETIHFEQQRTINQVRQRVFQQALQGALGTLNSCLTNELHLRTINANLGMFGAIKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TNIP3_HUMAN
Sequence: MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMYCPPCNCGLVFHLQDPWVPTGPGAVQKQREHPPDYQWYALDQLPPDVQHKANGLSSVKKVHP
What is the function of this protein?
Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate.  Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB.  NF-kappa-B inhibition is independent of TNFAIP3 binding.
What are the official names of this protein?
TNFAIP3-interacting protein 3, A20-binding inhibitor of NF-kappa-B activation 3, ABIN-3, Listeria-induced gene protein.
Protein: CAS6A_SACS2
Sequence: MPLIFKIGYNVIPLQDVILPTPSSKVLKYLIQSGKLLPSLNNLITSRDKYKPIFISHLGLNQRRIFQTNGNLKTISRGSKLSSTIAFSTQVNVLPELDEGVFETIYGKFHITIESVEIVEVEKLKEEVEKHMNDNIRVRFISPTLLSSKVLLPPSLSERYKRVNAGYSTLPSVGLIVAYAYNVYCNLIGKKEVEVRAFKFGVISNALSRIIGYDLHPVTIVIGEDSKGNLRKARGVMGWIEFDIPDEKLKRRALRYLLASSYLGIGRSRGIGFGEIKLEFIKREENH
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas6 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas6 family.
Protein: NU133_ARATH
Sequence: MFSPLTKRAKQSSRNEKTPRNRVPPPDSPVTPATQNRNNFISDRPATGTPAPWAPRLSVLARVSPGNNGDKGVDSDQLKPVFVGEFPQLLRDEQSYPGDACVSGGMDKETCLSWFITGSKVFVWSHLTTLPSRKCVVLELPVVVLVNEESGSGLQDGKSWLVNVVSWDTSAGAATRASRSRSPVGVVMCNRKTRAVVYWSDIFSGQEAAPAEKARHLIKRQSNGIRSSRAENSDLNSLITTAVAAAERLCIAIACSSNGELWQFTCSPTGVKSNQVQLNISSSSVSEGYPRSLIWRFSQGLARESCWEFLMLTDCDIHCFTIEPYPDLTVSEVWQHEIVGTDGDSGIKKDIASQKQIWPLDLQVDDQGKVITVLVATICMDRASSSSYTQYSLLTLQHKSEMRFADGREEKVLEKQGPIQVIIPKARVEDKDFLFSMRLRVGGRPPGSAIILSGDGTATVCYCHGSSTRLYKFDLPYDAGKVLDASVLSSTDEHEYGAWTVLTEKAGVWAIPEKAVVLGGVEPPERSLSRKNSSNERSTRDETRVTPYGVDRTAGRENSDIQNIEDKGNPKMGFTRQTARDEESEALLGQLFEGFLLSGKVDGSLEKLSQSGAFDRDGEANVFARKSKSIVDTLAKHWTTTRGAEIVAMTVISSQLVEKQQKHENFLHFLALSKCHEELCSKQRHSLQIILENGEKLAAMIQLRELQNMINQNRSARFGSPQAGSEDQVSCALWDLIQFVGERARRNTVLLMDRDNAEVFYSKVSELEEVFYCLNRQLEYIIRADQPLGTQLQRACELSNACVTILQTALDYKNEHQMWYPPLEGLIPWHSQTVVCNGLWCIASFMLHLLTEASRIDISAKSDIYTHLEVLTEVLLEACAGSTFAKLEREEENKGLLNEYWTRRDTIFDSLYRQAKEFMEAEIQGIRERTEATDEDIFRNRCSNLISIAKRHAGYKIMWKICYDLNDTGLLRNLMHEGVGPQGGFSYFVFQQLYDMKQFSKLLRLGEEFQDELLIFLKRHSDLVWLHQVFLHQFSSASDTLHTLALSQDEESMTTVEERTGPEPEDVQPTFADRKRFLNLSKIAYVADKDADSESKVKRIEADLNLLKLQEEITKALPNGEARNRLFRPEELIETCLNIQGRWTAIKAFEVFAWTSSSFRENHRSLLEECWRNAADQDDWDRHHQASTNEGWSEEETLQNLRNTALFQASKRCYGPTRVNTFDGDFAQVLPLRRENPEDSTSSVEDVLMSHKDFAEAGKLMLTAIMLGCVEEEGIVAEEFSSPME
What are the official names of this protein?
Nuclear pore complex protein NUP133, Nucleoporin 133, Nucleoporin Nup155-like.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin Nup133 family.
What are the subcellular locations of this protein?
Nucleus envelope. Nucleus, nuclear pore complex.
Protein: MTLD_ALISL
Sequence: MKAVHFGAGNIGRGFIGKVLSDSNVAVTFADVDAPLVDQLCHDQSYKVKVVGSKCQIDTVTHVTAVNSTSDDVIERIVHTDLVTTAVGPNVLNIIAKTIAKGLTKRFEANNESPLNIIACENMVRGTTHLKNEVYSHLDDSFHARCDELVGFVDSAVDRIVPPSEAANDDLLEVTVESFSEWIVDEKQFKGGVPNIAGMEKTDNLMAFVERKLFTLNTGHCITAYLGALKGHETVRDAIQDPEIRTEVKAAMEESGEVLIRRYGFDKELHAAYIEKILGRFANPYLRDEIDRVARQPIRKLGENDRLIKPLLGTIEYGIENKTLLKGIAAAFKYVNDTDPQAVELQTHLQESGLKATLAHYTGLNENSSEAKKIEAIFTTLN
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: FER3_CHLTE
Sequence: MSLKITEECTFCAACEPECPVNAISAGSDIYVIDESACTECEGYADSPACVAVCPAECIVKA
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin-3, Ferredoxin III, FdIII.
Protein: PSAM_EUGSA
Sequence: MAIDNTQIFIALLTALIPAFFALKLGKELSK
What are the official names of this protein?
Photosystem I reaction center subunit XII, PSI-M.
What is the protein family that this protein belongs to?
Belongs to the PsaM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FABV_PSEPK
Sequence: MAIIHPKVRGFICTTTHPKGCELNVRDQIEATRKLGVREDGPKKVLVIGASSGYGLAARITAAFGFKADTLGVFFEKPGTETKAGTAGWYNAAAFDKFAKAEGLYSKSINGDAFSDEARAKVIELIKNEMGGKVDLVIYSLASPVRKLPQTGEVIRSALKPIGQPYKSTAIDTNKDTIIEASIEPATEQEIADTVTVMGGQDWQLWIDALAGANVLAEGARTVAFSYIGSDITWPIYWHGALGQAKQDLDETALRLNQKLAGEVKGGANVAVLKSVVTQASSAIPVMPLYLSMVFKIMQEKGVHEGTQDQLDRMYRDRMYRTDGAPAEVDEKGRLRLDDWELRDDVQNACKALWPQVTTENLFELTDYAGYKKQFLNLFGFERADVDYDKDVATDVKFDCVEL
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: DNAK_BACMK
Sequence: MSKIIGIDLGTTNSCVAVMEGGEPKVIPNPEGNRTTPSVVAFKNEERQVGEVAKRQAITNPNTIMSVKRHMGTDYKVEVEGKDFTPQEISAIILQNLKASAEAYLGETVTKAVITVPAYFNDAERQATKDAGRIAGLEVERIINEPTAAALAYGLEKQDEEQKILVYDLGGGTFDVSILELADGTFEVISTAGDNRLGGDDFDQVIIDHLVAEFKKENSIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFISAGAAGPLHLELTLTRAKFEEISAGLVERTLEPTRRALKDAGFAPSELDKVILVGGSTRIPAVQEAIKRETGKEPYKGVNPDEVVALGAAVQGGVLTGDVEGVLLLDVTPLSLGIETMGGVFTKLIERNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMSADNKTLGRFQLTDLPPAPRGIPQIEVTFDIDANGIVNVRAKDLGTSKEQTITIQSSSGLSDEEVDRMVQEAESNADADQKRKEEVELRNEADQLVFQTDKVVKDLEGKVDAAEVAKATEAKEALQAAIEKNELEEIRVKKDALQEIVQQLTVKLYEQAQAAAGQAEGAQGAQDAGAKKDNVVDAEFEEVKEDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PSBJ_PROM5
Sequence: MSKLKGPDGRIPDRLPDGRPAVAWERRWTEGTLPLWLVATAGGIAVIFVLGIFFYGSYQGVGAG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: GRIK2_RAT
Sequence: MKIISPVLSNLVFSRSIKVLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRRLPGKETMA
What is the function of this protein?
Independent of its ionotropic glutamate receptor activity, acts as a thermoreceptor conferring sensitivity to cold temperatures (By similarity).  Functions in dorsal root ganglion neurons (By similarity).
What are the official names of this protein?
Glutamate receptor ionotropic, kainate 2, GluK2, Glutamate receptor 6, GluR-6, GluR6.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK2 subfamily.
Protein: CY552_BRADU
Sequence: MHLHLRGICLVLAVASSSSSALAADAGHGADLAKRWCASCHVVANGQAVASADVPSFASVARRPDFSSEKLAFFLLDPHPKMPSFPLSRTEAGDIAAYIGSLRP
What are the official names of this protein?
Cytochrome c-552, Cytochrome c552.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LUCA_MYCTU
Sequence: MGRKVAVLWHASFSIGAGVLYFYFVLPRWPELMGDTGHSLGTGLRIATGALVGLAALPVVFTLLRTRKPELGTPQLALSMRIWSIMAHVLAGALIVGTAISEVWLSLDAAGQWLFGIYGAAAAIAVLGFFGFYLSFVAELPPPPPKPLKPKKPKQRRLRRKKTAKGDEAEPEAAEEAENTELAAQEDEEAVEAPPESIESPGGEPESATREAPAAETATAEEPRGGLRNRRPTGKTSHRRRRTRSGVQVAKVDE
What is the function of this protein?
Required for the import of both fatty acids and cholesterol during growth in macrophages and in axenic culture.  Facilitates the uptake of these lipids by stabilizing protein subunits of the Mce1 and Mce4 multi-subunit transporters, which transport fatty acids and cholesterol, respectively.  Required for full virulence in vivo.
What are the official names of this protein?
Lipid uptake coordinator A.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURA_SHEPW
Sequence: MDKLKIEASGALAGDVVISGAKNAALPILMAGVLAETDFNVSNVPSLRDVNTSCELLRCLGAEVTRSGDDKVCISTTNLNEFCAPYELVKTMRASILILGPLLARYGKADVSLPGGCAIGARPVNLHLQGLEQMGAKIEVKEGYIKARVDGRLKGAHIFMDMISVGATENLLMAAALADGETVIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYQVMPDRIETGSFLVAAAVTRGKIRCIKADPKSLEAVLAKLEDAGASITTGDDWIELDMQGQRPKAVNIKTVAYPGFPTDMQAQFCVLNALAEGTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIEKLNGAQVMATDLRASASLVIAGLVADGTTTVDRIYHLDRGYEHIEDKFKGLGGDVKRVK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.