PharMolix/UniProtQA huggingface dataset:
Protein: GCSH_SYNS9
Sequence: MAFEFPAAYRFADSHEYAHLDGELIRVGISAFAVDQLGDIVFVDLPDVGASLDKGTSFGSVESVKAVEDMYAPIAGEVVERNEAVLASPEELQNDPHGAGWLLVVRPSDPAQLETLLDSATYSAKVNAG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: MNMA_BURCJ
Sequence: MSKRRVVVGMSGGVDSSVTAWLLKEQGYDVVGLFMKNWEDDDDGEYCSTRQDWIDVVSVADLIGIDVEAVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLDAEMIATGHYARVRERDGRFELLKAFDHTKDQSYFLHRLNQAQLSKTMFPLGEIPKTKVREIAAQIGLPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTPDGKVVGEHIGLAFYTFGQRKGIGLGGSKSGSGEPWFVAAKDIASNTLYVVQGHDHPWLLSRELVAGNVSWVAGEPPADGFACGAKTRYRQADAACVFGLAATGAEAAGPAGEARFSLAFDDAQWAVTPGQSAVLYDGEICLGGGIIESAATGQPGQATSTGHAPALAEAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCCIP_XENLA
Sequence: MASNAKRRALEPERLLEKHKEDEEDMEGDESEESDDIEEDESEEDEEVNEEVNIDFEAYTISDADYDGIKKLLKQLFLKAHVNISELTDLLIQQNHIGSAIKQAEGQDDSDDDEDDDHVFGVISLVNLTERKGTACVEQIKELILSRCEENCEQSLVEQFDKVLNDNSKPVGFLLSERFINVPAQIALPMHQQLQKELADSQRTNKPCGKCHYYLILSKTFMEATKTSKGSVGSQAKEELMFANAEDEFFYEKALVKFNYSVQEESDTQLGGRWSFSDVPMKPLRTAMLVPAERMNSIMDKFKEYLSV
What is the function of this protein?
During interphase, required for microtubule organizing and anchoring activities.  During mitosis, required for the organization and stabilization of the spindle pole.  May promote cell cycle arrest and DNA repair.
What are the official names of this protein?
Protein BCCIP homolog.
What is the protein family that this protein belongs to?
Belongs to the BCP1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole.
Protein: NQRC_HAEIN
Sequence: MAKFNKDSVGGTILVVLLLSLVCSIIVAGSAVMLKPAQEEQKLLDKQKNILNVAGLLQENTNVKETYAKFIEPRFVDLATGEYTQQADDSQQAIPADADKARIRSRSKTTEVYLVKDEQGQTQQVILPIYGTGLWSVMYGLVSVQPDGNTINGITYYQHGETPGLGGEIENPNWASLFKGKKLFDEQHQPAIRIVKGQAPQDEHSIDGLSGATLTGNGVQGTFNYWFSKDGFGPYLEKLHSGAN
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit C, Na(+)-NQR subunit C, Na(+)-translocating NQR subunit C, NQR complex subunit C, NQR-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the NqrC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MURG_SYNR3
Sequence: MPRLLIAASGTGGHLFPALAVADRMPETWSVRWLGVPDRLERQLVPSRYPLFTVRAGGLQGRGLRKLKQLIQLLWSAWPVTRLIRKQECAVVFTTGGYIAAPAILAARLCRRPVVLHESNAIPGQVTRLFGRFCSRVALGLPQAADYLSGCRPEVTGTPVREDFLKPAACPDWVPAGDGPLLLVIGGSQGAVGLNRMVRAAAPALLAMGCRIVHLSGHVDPDQGQLEHPAYSERPFSEEIPALLQHADLAISRAGAGSLSELAVCGTPAVLVPFPQAADDHQSANAAAAAAVGAAVIVAQHGPNEPGLRRMLWNLLGPRLRGCDPAADPLRLLRQGMERLAVRDADRLLSQLLQDLAAEA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL25_XANP2
Sequence: MTAIKELKAVARPRAGKGAARAERRAGRVPAVIYGEKQEPVTISLNFREINKTIYAGHFLTTLFEIDVDGTKHRVIPRDYQLDVVKDFPLHVDFLRVSQGATVTVEVPVHFLNQEASPALKAGGTLNVVAHAVELECPAESIPASVEVDLTGAAYGDTFHLSGIKLPAGVTWAGHGDDTLATVVAPSGQADAAAEDAAEAAKA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: MU115_SCHPO
Sequence: MRKPCYAVYHPALRLKCLVRKGLGKIKGDTDMCDKQQLKKKEKEKQRAQKVACGPRDPPCTFSRSYTDQKRKEIHLGSTEWGLKESFTLTRGPNRRGNVGKGVKRPMVNKKLGQLELTSLDLRWQKEGKGN
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 115 protein.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus.
Protein: DAPF_ECO24
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15E_METM7
Sequence: MSMYNYVKEAWKVPANSYVKELQWSRMQDWRKEPSVIRVERPTRIDRARNLGYKAKQGIVVVRVSVRRGGLRKPRPKHSKKPSTLGINKITMAKSIQRIAEERAAKKYPNLEVLNSYWVGQDGKQKWYEVILVDSCHPSIKSDKSYNWLCKGTHKGRATRGLTSAGKKGRGLMYKGKGTEKVRPSVRANSKKAK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: GON2_ALLMI
Sequence: QHWSHGWYPG
What is the function of this protein?
Stimulates the secretion of gonadotropins.
What are the official names of this protein?
Gonadoliberin-2, Gonadoliberin II, Gonadotropin-releasing hormone II, GnRH-II, Luliberin II, Luteinizing hormone-releasing hormone II, LH-RH II.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: CL4B2_GLORO
Sequence: MATNTMLCLLILSVVLALAFATNKKGDEEPENHSTGIFGKVGRVVTVALAMSSRLGGADATRGGGAVYGGNLKSNQLPNNNWMAPPPPMAIRSAKVYDSKHSPAEYLKKFAQDFRRKTGMHSQRHHEETTLEQEKRVAGAGPDPIHHEETTLEQEKRAVPAGPDPKHHEETTLEQEKRAVPAGPDPKHHEETTLEQEKRAVPAGPDPKHHEETTFEQEKRGAPAGPDPIHH
What is the function of this protein?
Mimics host plant CLE extracellular signal peptides that regulate cell fate.  May play a role in the differentiation or division of feeding cells (syncytia) induced in plant roots during infection.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 4B-2.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host extracellular space. Secreted, extracellular space, apoplast. Note=Present in secretory granules within the dorsal esophageal gland secretory cell and in the dorsal gland ampulla (collecting reservoir) at the base of the nematode stylet. Secreted into host root cells via the nematode stylet to transform the recipient cells into enlarged multinucleate feeding cells called giant-cells or syncytia. Secreted to the host apoplasm from its cytoplasm via a plant secretory pathway (By similarity).
Protein: GT102_ORYSJ
Sequence: MAAPPCPPRRPISAPCFLLCFLLGFVAGLFPFAHRHLHLDLHLPLPPPATAILVREDPPSVVVDVDTPLPAAAEERKLLLVVTPTRARPLQAYYLRRLAHTLRLAPSPLLWLVVESGAATRDTAALLRGCGVMYRHLSSPVPDAPQDRPRRRGRRQDRPAVDSRARQRNTALDHIEHHRLHGIVYFADEDNVYSLDLFYHLRDIRSFGTWPVATLAPGKSKTILQGPVCEGSRVVGWHTTDRSKNQRRFHVDMSGFAFNSSKLWDAKNRGHQAWNYIRQLDTAKEGFQETAFIEQLVEDETHMEGVPPGCSKIMNFHLHLEDKNAIYLNGWQTTQNLDVIIPLKKEARPLL
What is the function of this protein?
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
What are the official names of this protein?
Probable glucuronosyltransferase Os10g0205300.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 43 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PDXT_STRZT
Sequence: MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSGLILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGTMDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVAAQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: THIG_PHOV8
Sequence: MKKLIIAGKEFNSRLFLGTGKFNSNTVMEEAILASGCEMVTVAMKRIELDDKEDDMLKHIIHPHIQLLPNTSGVRTAEEAVFAAQMAREAFGTNWLKLEIHPDPRYLLPDSTETLKATEELVKLGFVVLPYCQADPTLCKRLEEAGAATVMPLAAPIGTNKGLQTRDFLRIIIEQASVPVVVDAGIGAPSHATEAMEMGADACLVNTAIAVAGQPVEMAIAFKEAVIAGRRAYEAGLGAVGQNLIASASSPLTSFLD
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_SODGM
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQVAQALERMGVDVMEVGFPVSSPGDFESVQTIARQIKNSRVCGLARCVDRDIDVAAEALRVAEAFRIHLFLATSTLHVESKLKKSFDQVVEMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRIVEATIKAGARTINIPDTVGYTTPNQFGGIISSLYQHVPNIDKAIISVHCHDDLGMAVGNSIAAIQSGARQVEGTLNGIGERAGNTALEEVIMAIKVRQDLLNVHTGIHHQEIYRTSQVVSQLCNMPIPANKAVVGANAFAHSSGIHQDGVLKNRQNYEIMTPEIIGLKEVQLNLTSRSGRAAVKHRMQEMGYQESNYSLDELYDAFLKLADKKGQVFDYDLEALAFINNQQEQSEHFRLEYFSVQSSSADIATASVKLAFGDEVHAEAATGNGPVDAVYEALNRITQLPIQLEKYQLTAKGHGRDALGQVDIVVEYEGRRFHGVGLATDIIESSALAMVNSMNTIWRARQVGIELRRLHQHNNSQDMQETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RL14_CORA7
Sequence: MIQQESRLRVADNSGARELLVIRVLGGSVRRFAGIGDIVVATVKEAIPGGNVKEGDIVKAVIVRAKKETRRPDGSYIAFDENAAVILKGDNEPRGTRIFGPVARELRDKRFMKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ATRDH_AGRFC
Sequence: MHAIQFVEKGRAVLAELPVADLPPGHALVRVKASGLCHTDIDVLHARYGDGAFPVIPGHEYAGEVAAVASDVTVFKAGDRVVVDPNLPCGTCASCRKGLTNLCSTLKAYGVSHNGGFAEFSVVRADHLHGIGSMPYHVAALAEPLACVVNGMQSAGIGESGVVPENALVFGAGPIGLLLALSLKSRGIATVTMADINESRLAFAQDLGLQTAVSGSEALSRQRKEFDFVADATGIAPVAEAMIPLVADGGTALFFGVCAPDARISVAPFEIFRRQLKLVGSHSLNRNIPQALAILETDGEVMARLVSHRLPLSEMLPFFTKKPSDPATMKVQFAAE
What is the function of this protein?
Involved in D-altritol catabolism.  Catalyzes the oxidation of D-altritol to D-tagatose.
What are the official names of this protein?
D-altritol 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RL35_HALHL
Sequence: MPKLKTNRGAAKRFKVKASGRISRARSNHSHILTKKDPKRKRRLRELTEVHASDAPMVRRMVAK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: SSU72_MOUSE
Sequence: MPSSPLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCTDLFDLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQHTEDMENEIDELLQEFEEKSGRAFLHTVCFY
What is the function of this protein?
Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II.  Plays a role in RNA processing and termination.  Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK.
What are the official names of this protein?
RNA polymerase II subunit A C-terminal domain phosphatase SSU72, CTD phosphatase SSU72.
What is the protein family that this protein belongs to?
Belongs to the SSU72 phosphatase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly in the cytosol.
Protein: GLGC_METCA
Sequence: MPESMHASSRFVSRLTRQTLALILAGGRGSRLQKLTEWRAKPAVPFGGKFRIIDFPLSNCVNSGIRQVGVLTQYKADSLIRHIQQGWGFLRGELGEFIDIMPAQQRLQESWYAGTADAVYQNLDIIRQRDPEFIMILAGDHVYKMDYGLMLAYHVERKADLTIGCMEVPLADAKAFGVMQMDGEQRIRKFVEKPSDPPPMPNRPDHAAASMGIYIFNTAFLFEQLIKDADTPGSNHDFGMDIIPQVIQKYRVFAYRFRNAQSGVQAYWRDVGTVDSYWAANMELIGVDPELNLYDQEWPIWTYQAQTPPAKFVFDDDDRRGMAVDSMVSGGCIISGAEVRHSLLFSNVRVNSFSRVLDSVILPDVNIGRHCRISRAVIDKGCNIPPNTVIGENLEDDRKRFYVSPEGIVLVTPDCLGQRLHFHR
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: ATPB2_PHOPR
Sequence: MSTGKIVKVIGAVVDVEFDQDSVPRVYDALNIIDGNNSSLVLEVQQQIGSGIVRCIAMGSSDGMRRGLVAVNTGEPITVPVGEETLGRIMNVLGQPIDECGEIGQKTSYPIHREPPSYEDQANSTELLETGVKVIDLICPFAKGGKIGLFGGAGVGKTVNMMELINNIAKAHSGLSVFTGVGERTREGNDFYYEMKEAGVLDKVAMVYGQMNEPPGNRLRVALTGLTIAERFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTHKGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRNIAALGLYPAIDPLDSTSRQLDPLVVGVEHYDVARGVQTVLQRYKELKDIIAILGMDELSEDDKLTVARARKVERFLTQPYHVAEVFTGQPGIFVSLKDTLNGFKGLLSGEYDDVPEQAFLYCGAIEDVIEKAKTM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MAAI_HUMAN
Sequence: MQAGKPILYSYFRSSCSWRVRIALALKGIDYKTVPINLIKDRGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA
What is the function of this protein?
Bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity.  Has also low glutathione peroxidase activity with T-butyl and cumene hydroperoxides.  Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid.
What are the official names of this protein?
Maleylacetoacetate isomerase, MAAI, GSTZ1-1, Glutathione S-transferase zeta 1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Zeta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF43A_ORYSJ
Sequence: MAAATTSRRGPGAMDDENLTFETSPGVEVISSFDQMGIRDDLLRGIYAYGFEKPSAIQQRAVLPIISGRDVIAQAQSGTGKTSMISLSVCQIVDTAVREVQALILSPTRELAAQTERVMLAIGDFINIQVHACIGGKSIGEDIRKLEHGVHVVSGTPGRVCDMIKRRTLRTRAIKLLILDEADEMLGRGFKDQIYDVYRYLPPELQVCLISATLPHEILEMTSKFMTDPVRILVKRDELTLEGIKQFFVAVEKEEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTERMRSNNFTVSAMHGDMPQKERDAIMGEFRSGATRVLITTDVWARGLDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKKEDIRILRDIEQYYSTQIDEMPMNVADLI
What is the function of this protein?
ATP-dependent RNA helicase.  Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD).  Its RNA-dependent ATPase and RNA-helicase activities are induced by MLN51/CASC3, but abolished in presence of the MAGO-Y14 heterodimer, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation.  The inhibition of ATPase activity by the MAGO-Y14 heterodimer increases the RNA-binding affinity of the EJC (By similarity).  EJC core proteins play essential roles in rice development, growth and reproduction.  Regulates the splicing of UDT1 (UNDEVELOPED TAPETUM 1) pre-mRNA transcript.  UDT1 is a key regulator in stamen development (PubMed:27071313).
What are the official names of this protein?
Eukaryotic initiation factor 4A-III homolog A, OseIF4AIIIa, eIF-4A-III, eIF4A-III, DEAD-box ATP-dependent RNA helicase 2, OsRH2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleocytoplasmic shuttling protein. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA.
Protein: RUVB_PSECP
Sequence: MAEPSLVAAGEEPEERAIEAALRPKNLDDFVGQHRVRKQLSLVLKASRMRGRSADHVLFSGPPGLGKTTLAMIVAAEMNAPLRISSGPAIQHAGDLAAILSSLSEGEVLFLDEIHRMSRPAEEMLYMAMEDFRVDIVVGKGAGATAIPLELPPFTLVGATTRAGLLPGPLRDRFGFTGHLEFYSVPELELVLRRSAGLLDLKVNSAGFSEIAGRSRGTPRIANRLLRRVRDWALVHGVDQIDARSASAALDMYEVDKKGLDRLDRSVLEALITKFGGGPVGLSTLAIAVGEETETVETVAEPFLVREGLLGRTPRGRIAMAPAWTHLGYAIPAGVFGQEQLDLFDRETGAEVTGEWAPESQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RL16C_SCHPO
Sequence: MSEFQKLVIIDAKGHLMGRLASTVAKQLLAGQKVVVVRCEELNISGHFFRNKLKYLAYLRKACRYNPSRGAFHFRAPSRIFTKAVRGMLPHKTTRGNIALKNLQALEGIPPPFDKQKRLVVPAALRVLRLKPSRKYCTIGRLSSEVGWKYKNIVSKLEERRKIKSAAFYQAKSANQKHINVAKTKSSVNEKLAVFGY
What are the official names of this protein?
60S ribosomal protein L16-C.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PCNA_METKA
Sequence: MVEFRAYQEEARYFKYAFNAAGKVVEEAPLIVTENGIVSRAMDASHIAMAVLEMPWEMFDEYEPPSDELMYGLDMEEVTRIVRRARVTDEITLEGEDEEEVIIKLGSSGYEREFRLRSIDIDDIPDEPELDFAVEVTVVPDFIQDAVRDADLVSDTVKVGAKGNTFYFKAEGERGRVIPKVQEGAEALLTFEVEEDVETAYPLDYLKDMIQAAQGAESVRIRLGQDMPLELTFRIGPAGEGKLTFYLAPRVEE
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: GLPK_SALDC
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIVSVSQREFEQIYPKPGWVEHDPMEIWASQSSTLVEVLAKADISSDQIAAIGITNQRETAIVWERETGKPIYNAIVWQCRRTADICEQLKRDGLEDYIRDNTGLVVDPYFSGTKVKWILDHVEGSRERAKRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHDLDWDDKMLDVLDIPRAMLPQVRKSSEVYGQTNIGGKGGTRIPIAGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPSGEVNYALEGAVFMAGASIQWLRDEMKLISDAFDSEYFATKVKDTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNSNHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGYWQNLDELQEKAVIEREFRPGIETTERNYRYSGWKKAVKRAMAWEEHDK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: ACCA_BRASO
Sequence: MPDPMRSYLDFEKPVAELDSKVDELRAMAASGTDIGEEVSRIEEKAGQALADLYANLTPWQKTMVARHPQRPHFTDFVNALITEFTPLAGDRKFGEDAALLGGFGRFRGEPICVMGQEKGATTESRLKHNFGMARPEGYRKAVRLMEMAERFGLPVLSLVDSAGAYPGIGAEERGQAEAIARSTDACLALGVPNVAIITGEGMSGGAIALTTANKVLMLEHAIYSVISPEAASSILWRDGTKAQEAANSMKITAQDMLRFGVVDTILKEPVGGAHRDPAAMIAATGDAIAQAFDELKGLDAAAIRKQRRQKFIEIGRKLS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.