PharMolix/UniProtQA huggingface dataset:
Protein: KDPC_BACCR
Sequence: MEKKQSILSPIIRITFTFLVLCGLVYPLIVTGIAQAVMKDNADGSLIYNDKNEVIGSKLIGQNFTDPRYFQGRVSSIEYKAEASGSNNYAPSNPDLEKRVEKSIEEWKKQNPSVPVTEVPIDLVTNSGSGLDPDISPKAASVQVDRISKLTDIPKEKLNQLIKDQTEGAALGLFGETRVNVLKLNLALQELMK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HSPB6_HUMAN
Sequence: MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYLRAPSVALPVAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPPAAAK
What is the function of this protein?
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state.  Seems to have versatile functions in various biological processes.  Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility.  May regulate myocardial angiogenesis implicating KDR.  Overexpression mediates cardioprotection and angiogenesis after induced damage.  Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.
What are the official names of this protein?
Heat shock protein beta-6, HspB6, Heat shock 20 kDa-like protein p20.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=Translocates to nuclear foci during heat shock.
Protein: ARSH_HUMAN
Sequence: MTRNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRNDHCYHPLNHGFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFLLLIPKFARWFSVPWKVIFVFALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEKVASLMLKEALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFLFHYCGVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGDVTYHDPPLLFDISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPVPQQFSVFNTIWKPWLQPCCGTFPFCGCDKEDDILPMAP
What are the official names of this protein?
Arylsulfatase H, ASH.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y2304_ARTS2
Sequence: MSGHSKWATTKHKKAILDSRRAKSFAKLIKNIEVAARMGGPDLAGNPSLELAVTKAKKTSVPADNIDRAIKRGAGLTGEVVDYTEIMYECRGPQGSALLIECLTDNKNRAASEVRLAISRNGGTIADPGSVSYLFSRKGVVTLPKNGLSEDDVLMAVLDAGAEEVKDNGETFEIHSDPKDLQAVRDALKDAGIDYDTDEAEFVPSMEVPLDLDAAKKFMKLVDALEELDDVQNVYSNADLSDEVQAALEAE
What are the official names of this protein?
Probable transcriptional regulatory protein Arth_2304.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG20_MYCTU
Sequence: MSYMIAVPDMLSSAAGDLASIGSSINASTRAAAAATTRLLPAAADEVSAHIAALFSGHGEGYQAIARQMAAFHDQFTLALTSSAGAYASAEATNVEQQVLGLINAPTQALLGRPLIGNGADGTAANPNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAGLIGNGGNGGAGGAGANGGAGGNGGWLYGSGGNGGAGGAGPAGAIGAPGVAGGAGGAGGTAGLFGNGGAGGAGGAGGAGGRGGDGGSAGWLSGNGGDAGTGGGGGNAGNGGNGGSAGWLSGNGGTGGGGGTAGAGGQGGNGNSGIDPGNGGQGADTGNAGNGGHGGSAAKLFGDGGAGGAGGMGSTGGTGGGGGFGGGTGGNGGNGHAGGAGGSGGTAGLLGSGGSGGTGGDGGNGGLGAGSGAKGNGGNGGDGGKGGDAQLIGNGGNGGNGGKGGTGLMPGINGTGGAGGSRGQISGNPGTPGQ
What are the official names of this protein?
Uncharacterized PE-PGRS family protein PE_PGRS20.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
Protein: SUCC_PYRCJ
Sequence: MKLHEYEAKELFAKYGVKIPPGRLALTPEEVRKAAEEMGPPVVLKAQVVVAGRGKAGGIKVAKRVEEAYELSKQMFGMNIKGLTVRKLYVTKYLEVEREMYLSLIIDRATRRFLFLASPVGGMDIEEIAKTTPEKIKRVYVDPFVGLRDYHVRSIVSWLGFSPGTAQWQQAASIVQAMYKIAVDYDAELVESNPLALTKEGDVVPLDARVIVDDNALFRHPELEKALEEDPRDITEFEAYAKKIGFHYVELDGDIGIIGNGAGLTMATMDLVYHFGGRPANFLDIGGGASREVVREAVKVLLNHPRAKVIFINIFGGITRADEVAYGVKEALQAAGGTTKKIVVRMKGTNEELGRAILAEIGVPLFESAEEAAKKAVELAKL
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: LHTL2_ARATH
Sequence: MEKSQSSPTKDASTKQKNVDDWLPITSSRNAKWWYSAFHNVTAMVGAGVLSLPYAMSNLGWGPGVTIMIMSWLITFYTLWQMVQMHEMVPGKRFDRYHELGQHAFGEKLGLWIVVPQQLIVEVGVDIVYMVTGGKSLKKIHDLLCTDCKNIRTTYWIMIFASIHFVLAHLPNFNSISIVSLAAAVMSLSYSTIAWATSVKKGVHPNVDYSSRASTTSGNVFNFLNALGDVAFAYAGHNVVLEIQATIPSTPEKPSKIAMWKGVVVAYIVVAICYFPVAFVCYYIFGNSVDDNILMTLEKPIWLIAIANAFVVVHVIGSYQIYAMPVFDMLETFLVKKMMFAPSFKLRFITRTLYVAFTMFVAICIPFFGGLLGFFGGFAFAPTTYYLPCIMWLCIKKPKKYGLSWCINWFCIVVGVILTILAPIGGLRTIIISAKNYEFFS
What is the function of this protein?
Amino acid transporter.
What are the official names of this protein?
Lysine histidine transporter-like 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRUA_BREBN
Sequence: MKRLRCVLAYDGTDFSGFQVQPDQVTVQGEIEAALNRVTGEDIQVFGSGRTDAGVHARGQVIHFDTASNIPMDKWRFVLNNQLPDSIVIRTVEEVDASFHARFDVQVKEYRYCIDNNPVADVFRHRYADHVRFPLDVDAMQQAAHYLVGEHDFTSFCSAKTYVEDKVRTVYGLSVEKIGDEVWVTCRGNGFLYNMVRIIVGTLVEVGQGKRNPAELREILAACDREKAGKTAPAKGLTMWEVVY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LIPB_RICB8
Sequence: MVQFITIPTPIDYQDSLMLMEDYVNKVIDGEAPEAVYLVEHLDVYTAGTNYKQEELLNHNNIPVIYTGRGGKFTFHGAGQRVIYPILNLALPNRTKDLKLYVRMLEEWIINSLDIFGIKAYIIKNKVGIWVKTNDDIPSKIAAIGVRVRKWVTYHGIAINISTDLSKFNGIIPCGLENSLVTSLNQLGVYIEMTEFDKILEVEFIKIFK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_BRUME
Sequence: MNKPVAPNSYKTGPDEEGMFGIFGGRFVAETLMPLILELQQAYETAKNDPEFKAELNALSTFYAGRPSKLYYAEGLSKHLGGAKIYFKREDLNHTGSHKINNCLGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCIVYVGASDVERQKPNVFRMKLLGAEVKPVSAGNGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPELVRDFQSVIGTEARQQILEQEGRLPDVIVAAVGGGSNAIGLFHPFLDDASVKIVGVEAGGRGLEGEEHCASMSAGRPGVLHGNRTYLLQNADGQILEGHSVSAGLDYPGVGPEHSWLKDSGRVDYVPILDNEALDAFQLCTRTEGIIPALESAHAIAQAVKMAPTMGKDKVMIVNLSGRGDKDVHTVGKLLGMDI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: DBP10_SCHPO
Sequence: MSGFQTSDEVDISNSLKAFPVDIATDNQKDKHENVGENVSDEDDGNYIASKLLESNRRTKGKKGNGKASNFQSMGLNQTLLRAIFKKGFKAPTPIQRKTIPLLLEGRDVVGMARTGSGKTAAFVIPMIEHLKSTLANSNTRALILSPNRELALQTVKVVKDFSKGTDLRSVAIVGGVSLEEQFSLLSGKPDIVVATPGRFLHLKVEMKLELSSIEYVVFDEADRLFEMGFAAQLTEILHALPTSRQTLLFSATLPRTLVDFAKAGLQDPVLVRLDVESKVSADLQSAFFSVKTAEREAALLCILQDIIKLPLKDNVRPREIGNVNNPKKRKRALELALKGSESGSPDSTLVFVPTKHHVEYVSELLVQAGYSVSKIYGSLDQEARLNEINNFRLGKTNLLVVTDVASRGIDIPLLANVINYDFPPQPKVFVHRVGRTARAGRTGWAYSLVRAEDAGYLLDLQLFLNRPLVTSSKQVKTDSDCDFTKQIVLGSLPQELVAELLEWVQRIVSRDVELQQLSNVAARGEKLYFRTRATCSAESAKRAKELVDSKGWSSNNPLFGDVSVIEAEEKYAELLSKVSSYRPSETVFEIGQRGHLKTEAAEIMRKRRNKVKPKGIKSEVASDKITDSSPGNMSEASESELEEVFKNPKELSKKKTTDFKDKEYYMSHYAPKESIQETGYAINSGENFTTAARHAILDLTNDEGIEQSRKGGQRWDPKKKKFVNIINDEDGSKGSPKIIRGESGVKLPATYRSGRFDEWKASKAFGANDSPIRENKRYKHNKLQTPKPADKFRDNYHKQNKRNREAKERGIGIKVNSELKSAVEIRKARELKEKRLAKNNRPSKKHR
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ENOPH_ANOGA
Sequence: MAAVVALGANVLSAKSIICDIEGTTTSISFVKDTLFPYALKHVEGYLKNNWNEEATKTVVTALREQAEEDKKAEVEGVVPIPTGDSEDIIPEIVKNVEWQMSLDRKTGSLKTLQGLVWAKGYKDGSIKGHVYDDVQKAFEQWTENGRKIYIYSSGSVDAQKLLFEHSEQGDLLKYLSGHYDTKIGAKREKESYTSILKNIESSPEEALFLTDVYAEAKAAKEAGLNVVLLDRPGNSELSEEERKDFPVIATFSDLSFAAETKEENGGATNGKRKIEETNDDVAEEDKAQVYPNKK
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DAPE_COXB1
Sequence: MSETLNLLKQLIERPSITPNDAGCQTILIDRLKSVGFQCEHLPFGEVHNFWAWHGHQSPFIIFAGHTDVVPPGDETQWHSPPFTPTEKNGYIYGRGAADMKSGLAAMVVAAENFVKQNPDHNGTIGFIVTSDEEGPAENGTQKVVDYLQQKNIKLDYCIVGEASSNEKLGDAIKIGRRGSMHGELTIIGKQGHIAYPHLADNPIHRSFQAFEALAKTKWDEGNEHFTPTSFQFYNVEAGAGAANVIPATLKAKFNFRFAPIHTTQQLQQKVERILNYYQLNYDIQWNVSSQPFFSGNGRLATFVRQAIQEICHLNTEPNTYGGTSDGRFIATTGCEVIELGPVNKTAHHVNENICIADLEKLTDIYFRTLQLLT
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: Y3913_ARATH
Sequence: MIESVMAVRLSTGFCSSTALLQYRTAPSSEEGGNCFHYASRRVFQPQRIHHIDGSGFLKYNSDYITRKHLRKNRTQATAEYVDSASDPEKQTGKSRYHPSEEIRASLPQNDGDSRLSPAETTRTIIEVNNKGTLMLTGSIGDGVHENILWPDIPYITDQNGNLYFQVKEDEDVMQSVTSENNYVQVIVGFDTMEMIKEMELMGLSDSDFETEDDESGDDDSEDTGEDEDEEEWVAILEDEDEDDDDDDDDDEDDDDSDSDESLGDWANLETMRSCHPMFFAKRMTEVASNDPVDWMDQPSAGLAIQGLLSHILVEDYSDIQKKLADSNSTTNGNKDAENLVDKLEDNSKAGGDESEIDSSQDEKARNVVAFYKLEMIRIQLITAQGDQTEVEVEDVRKAQPDAIAHASAEIISRLEESGDKITEALKSLCWRHNSIQAEEVKLIGIDSLGFDLRLCAGAKIESLRFAFSTRATSEENAEGQIRKLLFPKTNQSTQPKPK
What are the official names of this protein?
Uncharacterized protein At3g49140.
Protein: POPA_RALSO
Sequence: MSVGNIQSPSNLPGLQNLNLNTNTNSQQSGQSVQDLIKQVEKDILNIIAALVQKAAQSAGGNTGNTGNAPAKDGNANAGANDPSKNDPSKSQGPQSANKTGNVDDANNQDPMQALMQLLEDLVKLLKAALHMQQPGGNDKGNGVGGANGAKGAGGQGGLAEALQEIEQILAQLGGGGAGAGGAGGGVGGAGGADGGSGAGGAGGANGADGGNGVNGNQANGPQNAGDVNGANGADDGSEDQGGLTGVLQKLMKILNALVQMMQQGGLGGGNQAQGGSKGAGNASPASGANPGANQPGSADDQSSGQNNLQSQIMDVVKEVVQILQQMLAAQNGGSQQSTSTQPM
What is the function of this protein?
Acts as a specific hypersensitive response (HR) elicitor.  Has activity on tobacco (non-host plant) and petunia but is without activity on tomato (host plant); PopA3 seems to be more active than a PopA1-PopA2 mixture.
What are the official names of this protein?
Protein PopA1.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via a type III secretion system (TTSS).
Protein: CH60_RHILW
Sequence: MASKEIKFGRTAREKMLRGVDILADAVKVTLGPKGRNVIIDKSFGAPRITKDGVSVAKEIELEDKFENMGAQMVREVASKTNDIAGDGTTTATVLAQAIVREGNKAVAAGMNPMDLKRGIDLAVADVVKDLQAKAKKISTSEEVAQVGTISANGDKQVGLDIAEAMQKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFVTNPEKMIADLEDVFILLHEKKLSNLQSMLPVLEAVVQTGKPLLIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGTVISEDLGIKLESVTLDMLGRAKKVSISKENTTIVDGSGAKSDIEGRVAQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGSTEVEVKEKKDRIDDALNATRAAVQEGIVPGGGIALLRSSTKITVKGANDDQEAGINIVRRALQSLVRQIAENAGDEASIVVGKVLDKNEDNYGYNAQTSEFGDMIAMGIVDPLKVVRTALQNAASVASLLITTEAMIAELPKKESAGGGMPGGMGGMGGMDMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAC3_ARATH
Sequence: MSSSTDDAGTTTHSLQEFKLFETQSNFYMIGWDGSGVYRVLKIDRLDPSELNISQDSTHYTKKECYELLKRIHEGNKATGGLKLVTLCYGIIGFVKFLGPYYMLLITERRHIGDLFGHSVYAVSKSEIVALHNSTVQCNFANSRDENRYKRLLCMVDLTKDFFFSYSYNVMRSYQKNVCNYETGHNLYEKMFVWNEFLTRGIRHHLRNTLWTVALVYGFFKQASLSESGKDFKITLIARRSRHNAGTRYLKRGVNRNGDVANDVETEQIVSEDVPEDHPMQISSVVQNRGSIPLFWSQETSRLNLKPDIVLSKKEPNYEATRLHFDNLVERYGNPIIILNLIKTKERRPRESILREEFVNAIDFINKDLPEENRLRFLHWDLHKHFRSKTKNVLALLCKVATCALMLTDLFYYQVTPAMTIEDSMSLSSSSDADTGDISPHTSSDDDNGDHDSLEKKSSRSKNIAYGKCDVKPPRLQSGVLRTNCIDCLDRTNVAQYAYGWAALGQQLHVLGIRDVPAIELDDPLAISLMGLYERMGDTLAHQYGGSAAHNKVFSERRGQWRAATQSQEFLRTLQRYYNNAYMDADKQDAINIFLGTFQPEQGMPAIWELRSNSLSNGRNGEMNIGKDERFLVKRCLSDGDFLHESCTPLSAMSSNHESMPQKGFSAPLQHVSHILSESSSDIPVSNDVALSRCTPSMPRKQLFGDVQKVHRFGSDQVYFGGEEDMSSVSNFVDIEWLSSENPCENALFDRSSELTRNLTAETSSTENSVNGVGQSAPTISESGSSSSKGKEPMGTKIREDFPDSFKEWVAYGEALCH
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
What are the official names of this protein?
Phosphoinositide phosphatase SAC3, AtSAC3, Phosphatidylinositol 3,5-bisphosphate 5-phosphatase SAC3, Protein SUPPRESSOR OF ACTIN 3, SAC domain protein 3.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: DER_SYNSC
Sequence: MTRPVVAIIGRPNVGKSTLVNRLCRSREAIVHDQPGVTRDRTYQDGYWGDREFKVVDTGGLVFDDDSEFLPEIREQAALALEEASVALVIVDGQQGLTAADESIAEFLRSHRCPTLLAVNKCESPEQGLAMAGEFWSLGLGEPHPISAIHGAGTGELLDQVLTFLPPKDQEGDEEEPIQMAIIGRPNVGKSSLLNAICGEQRAIVSPIRGTTRDTIDTSIIRENRPWRLVDTAGIRRRRSVNYGPEFFGINRSFKAIERSDVCVLVIDALDGVTEQDQRLAGRIEEDGRACVVVVNKWDALEKDSHTMTAMEKELRSKLYFLDWAPMLFTSALTGQRVESIFALAALAVEQHRRRVSTSVVNEVLKEALSWRSPPTTRGGRQGKLYYGTQVASRPPSFTLFVNDPKMFGETYRRYVERQIREGLGFDGSPLRLFWRGKQQRDAERDLARQQSRKG
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: CRG1_XENLA
Sequence: MGKIFFYEERNFQGRHYECGSDYSDLSSYFNRCNSIRVEGGNWILYEHPSYKGNQYYLWKGEYPDFQRWMGFNDSIRSCRFLPNYQGQYKMRIYERGDYQGQMMEFFDDCPNTYERFNFHDIHSCNVFDGHWMFYEEPNYRGRQYYLRPGEYRRYNDWGASSPRIGSFRRVYHRF
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin-1, Gamma-1-CRY, Gamma-crystallin I.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: CAIC_SALDC
Sequence: MDIVGGQNLRQMWDDLAGVYGDKTALIFESCEGIVRQFSYASLNEEINRTANLFYSLGIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESAWILQNSQVSLLVTSAQFYPMYREIRQDNSTPLNHICLIGEQLPADDGVSHFSQLQARQSATLCYTPVLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQIALRDDDVYMTVMPAFHIDCQCTAAMPAFSAGSTFVLLEKYSARAFWDQVRKYQATVTECIPMMIRTLMVQPAAPTDRQHHLREVMFYLNLSAQEKDAFTERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATARALEPEGWLHTGDSGYQDEDGYFYFVDRRCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIKDAIRDEAIKAFIVLNEGETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCSGKIIKKNLK
What is the function of this protein?
Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle.  Also has activity toward crotonobetaine and gamma-butyrobetaine.
What are the official names of this protein?
Crotonobetaine/carnitine--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: COQ7_FRATF
Sequence: MRKLSFLDRVIEELDSYARFTKVPLNPSKKSPSSDTIDGKLFEIEKKHSAGLMRVDYTGEICAQGLYRGQASVAKSPQTKEHLYHAAAEEYDHLAWCGERLQELGARPSLLNPFWYWTSFGIGAVAGSISDSLSYGFVVETEKQVMKHIDSHLKSLPVNDNRSREILKQMYIDESEHAVEAEKAGGKKLPKTVKAIMKLQSKVMTTLAYRF
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: IF2_NITWN
Sequence: MVDTKNPGDKTLSVSPTKTLTLKPRVEQGTVRQSFSHGRTKQVVVEKRGKRRIGGDSPGPEPAGTSEPASARTPAAKAPPARAATPAAPRAGSGVVLRKLTEDERSARASALAEAKVRAEEERRIAEAEAARRNSKEGIEQAEREAAEARRKAEEERHRQEEEAKRKAEIEAKRRFGQTESKPAPAKTTTTTTRAAPPARPAAVAADGSDEDEAPRLVRRPGGPARPVIAPKPAAKPAPAKQRGRLTLVTALSADDVRERSIASFRRRTQRLKGHASNEPKEKLVREVVVPEAITIQELANRMAERAVDVIRMLMKQGAMHKITDVIDADTAQLIAEELGHTVKRVAASDVEEGLFDVVDNSTDIEPRSPVVTVMGHVDHGKTSLLDALRHANVVSGEAGGITQHIGAYQVTSPESGKKITFIDTPGHAAFTAMRARGAKVTDLVILVVAADDGVMPQTIEAINHAKAAKVPMIIAINKIDKPEAKPERVRTELLQHEVQVESMGGQVVDVEVSAKNKTNLDKLLEMISLQADLLDLKTNASRPAEGTVIEAKLDRGRGPVATVLVQRGTLRVGDIIVAGAEMGRVRALISDQGETVNEAGPSVPVEVLGFNGPPEAGDRLAVVENEARARQVTSYRAHQKRENAAASTSGMRGSLEQMMSQLKTVGRKDFPLIIKADVQGSLEAILGSLEKLGTDEVAARILHAGVGGISESDVTLAEGFNAAIIGFSVRANKEAAAAAKRNGIEIRYYNIIYDLVDDVKKAMSGLLAPTLRETMLGNAEILEVFNISKVGKVAGCRVTDGSVERGANVRLIRDNVVVHEGKLSTLKRFKDEVKEVQSGQECGMAFESYGDMRVGDVIECYRVETIQRSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_BUCCC
Sequence: MRHYEIILMINPEKNKKIFIIIEEYNKLIHMYKGIIHRFEDWGKRSLSYTIKNLKKAHYFLMNIEVSSECIKELENSFKFNINIIRYFILTRTKAHKKISPILKNKEENKKELNSSVIKINKNIKKK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: IPRA_ECOLI
Sequence: MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNNEDTFVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQTITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRIGVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY
What is the function of this protein?
Involved in oxidative stress resistance.
What are the official names of this protein?
Inhibitor of hydrogen peroxide resistance.
What is the protein family that this protein belongs to?
Belongs to the IprA family.
Protein: SYL_PELTS
Sequence: MKERYDFKEIEEKWQARWAAQDLYAVPDYSDRPKYYCLEMFPYPSGKLHMGHVRNYSIGDVVARFKTMQGYHVLHPMGWDAFGLPAENAAIKHGGVHPAEWTLDNIESMRAQLKQLGISYDWNREVATCHPGYYRWTQWLFLQLFHNGLAYKKKAAVNWCPGCATVLANEQVKDGGCERCKAPVEKRELEQWFFKITDYAERLLKDLELLEGWPEKVKIMQENWIGRSEGAEIDFKVEGSDDIITVYTTRPDTVFGVTYMVLAPEHPLVEKLIAGSKQEAEIKEFIRKVRNLREIDRTSTEAEKVGMPTGAHCINPLTGEKVPVLIANYVLMEYGTGCVMGVPAHDQRDFEFARKYGYPIRVVIQPPGVELDPAAMEAAYEEEGFLVNSGPFSGMPNKEAIRAITRHLEEKGRGRFRVTYRLRDWLISRQRYWGAPIPIIYCDRCGTVPVPESDLPVLLPMDVEFKPTGQSPLAECPEFVNAACPSCGGPGKRETDTMDTFMCSSWYYYRYTSPRDNDAPWDRNKVDYWLPVDQYIGGVEHAILHLLYSRFFTKVLYDLKLVSNLEPFSNLLTQGMVLKDGAKMSKSRGNVVSPEDIVARYGADTARLFILFAAPPERDLEWSDQGVEGCYRFLNRVWRLVMPLAGLLKEAPAAVSGKLVGANREMRRVTHSTIKKVTEDISARFNFNTAVSAIMELVNALYQFREIPESDRNPAVLREAVESLLLLLAPFAPHITEELWEATGHRGSIHLQPWPSYDPEAIAEDEITIVVQINGRVRERLLVPAGITPQEMQDRVMKEPRVMRMVEGKKVAKVITVPGKLVNIVIK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_RIPO1
Sequence: MTHPLIPQIINLATPIAEDRGLEVVDVVFQTNKRPPVLRVDIRNSQGETSLDDCEAVSRALEAVLDESQVMGGSYVLEISSPGISRQLHSDREFISFKGFAVIVTTEIPYLDHKEWRGQLQGRDESAVYINQKGRAIAIPRELIAKVQLDEHR
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBC9_HUMAN
Sequence: MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
What is the function of this protein?
Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451.  Can catalyze the formation of poly-SUMO chains.  Necessary for sumoylation of FOXL2 and KAT5.  Essential for nuclear architecture and chromosome segregation.  Sumoylates p53/TP53 at 'Lys-386'.  Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity (PubMed:26620705).
What are the official names of this protein?
SUMO-conjugating enzyme UBC9, RING-type E3 SUMO transferase UBC9, SUMO-protein ligase, Ubiquitin carrier protein 9, Ubiquitin carrier protein I, Ubiquitin-conjugating enzyme E2 I, Ubiquitin-protein ligase I, p18.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Mainly nuclear (By similarity). In spermatocytes, localizes in synaptonemal complexes (PubMed:8610150). Recruited by BCL11A into the nuclear body (By similarity).