PharMolix/UniProtQA huggingface dataset:
Protein: KAD_STAAS
Sequence: MNIILMGLPGAGKGTQASEIVKKFPIPHISTGDMFRKAIKEETELGKEAKSYMDRGELVPDEVTVGIVKERISEDDAKKGFLLDGFPRTIEQAEALNNIMSELDRNIDAVINIEVPEEELMNRLTGRRICESCGTTYHLVFNPPKVEGICDIDGGKLYQREDDNPETVANRLSVNIKQSKPILDFYDQKGVLKNIDGSKDISDVTKDVIDILDHL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A_CRYNB
Sequence: MSSGGKGKASSETKSSSRSSKAGLQFPVGRIHRLLKKGNYAQRIGSGAPVYLAAVLEYLAAEILELAGNAARDNKKSRIVPRHLQLAVRNDEELNKLLGSVVISQGGVLPHIMAELLPVKTKGKAKASQEV
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MDFI_HUMAN
Sequence: MYQVSGQRPSGCDAPYGAPSAAPGPAQTLSLLPGLEVVTGSTHPAEAAPEEGSLEEAATPMPQGNGPGIPQGLDSTDLDVPTEAVTCQPQGNPLGCTPLLPNDSGHPSELGGTRRAGNGALGGPKAHRKLQTHPSLASQGSKKSKSSSKSTTSQIPLQAQEDCCVHCILSCLFCEFLTLCNIVLDCATCGSCSSEDSCLCCCCCGSGECADCDLPCDLDCGILDACCESADCLEICMECCGLCFSS
What is the function of this protein?
Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis.  Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals.  Can also interfere with the DNA-binding activity of Myod family members.  Plays an important role in trophoblast and chondrogenic differentiation.  Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA.  Binds to the axin complex, resulting in an increase in the level of free beta-catenin.  Affects axin regulation of the WNT and JNK signaling pathways (By similarity).
What are the official names of this protein?
MyoD family inhibitor, Myogenic repressor I-mf.
What is the protein family that this protein belongs to?
Belongs to the MDFI family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: YNAI_ECOLI
Sequence: MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHAVQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDFICTSLIAVILTIKLFLLINQFEKQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAGKDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKITTFDNRPLYVPNSLFSSISVENPGRMTNRRITTTIGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLVYFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSHGADFAFPSQTLYMDNITPPEQGR
What is the function of this protein?
Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed.
What are the official names of this protein?
Low conductance mechanosensitive channel YnaI.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEPB_SALCH
Sequence: MTEAMKITLSTQPADARWGDKATYSINNDGITLHLNGKDDLGLIQRAARKIDGLGIKQVALTGEGWDTERCWAFWAGYKGPKGVRTVMWPDLDDAQRQELDNRLTIIDWVRDTINAPAEELGPEQLAQRAVDLLCSVACDSVTYRITKGEDLREQNYMGLHTVGRGSERPPVLLALDYNPTGDKDAPVYACLVGKGITFDSGGYSIKQSAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIIRYRNGKNAEVMNTDAEGRLVLADGLIDASAQHPQLIIDMATLTGAAKTALGNDYHALFSFDDTLAGRLLTSAAQENEPFWRLPLAEFHRNQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYREGWLHIDCSATYRKAPVEQWAAGATGLGVRTIANLLTA
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRTL_LACLA
Sequence: MLTNQELTAKVKEISLTYFKQSFDHEAKWNQRLRTTGGRFFPKDLHLDFNPKMAELKDFEGVILHELTHYHLYRSKRGYKHRDADFKRLLSQVGGLRYAPSVIDKKIKYYYSCQNCGQLYPRQRKIDTKKYRCGKCRGKLILKTSGN
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1898_STAA9
Sequence: MAVNLYDYANQLEQALRESEEYKAIKEAFANVKANEESKKLFDEFRETQINFQQKQMQGEEIAEEDLQKAQEQAQAIEKDENISALMNAEQKMSQVFQEINQIIVKPLDEIYAD
What are the official names of this protein?
UPF0342 protein SaurJH9_1898.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: HIS4_PARMW
Sequence: MEILPAIDLLDGACVRLHKGDYEQVTRFSDDPVAQALSWQQQGATRLHLVDLDGAKRGEPVNDSAVQAITSALDIPVQLGGGVRSLERAEQLLACGLDRVILGTVAIEQPDLVRSLAERYPGRIVVGIDAKDGRVATRGWIEQSDVLATDLARTFSSSGIAAIITTDIATDGTLAGPNLEALRTMAASSSVPVIASGGIGCMADLLSLLPLEPLGVSGVIVGRALYDGRVDLAEAVRALAEPRLQDITAVAADLA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP450_ARATH
Sequence: MFSIIFSNPVKPFNSVIIHQIRFFSRDPFPNKVQHYLYRANLIDSIRLSLRSPTTSDRTLASLLNHRLLDSFVVKNALRSSPSVSSAWSIFKTLSHKSPRFSFETETLHAFATVLAKFQRSSELNSLIGVVNAWKFRNVHFSFMNLLNLYATAGDFDSVLKTWDEYRCSGEEKKGCTESYNIVMQVYMTLGKDSEAVQTFDQIINEGGIPNSRTFTIMIEHLVKLGNLDAAMKIFETLPLMRITRTLKHYSVLVEAFVDAQRFDEVKTLIAEMKSDGKFPSRRMLEPLKRMREAGFEHETEEFLREMLPDERIKDISMYSMDNPSDSEDEGDEYKDDVNEAQVKLKPWLDPKALATSLKKWSSDAVTALEEANFVWTNLLVCKMLRNFRAPETAWSFFCWVAIQPGFTHDAYTIERMMAMLARNGQVELVDKLISKVRIEGIKLPFSTIRLIIDLYGISKKPEAAIKVFNEDRTLCGSISDFNLMLLYSSLLRTLTKCKRNAEALETLEDMMLTGVSPDIQTFSGLMYHFALQGEIQTVERLFSMVRQIGLEPDPYMLKLLVQAYCRCERSVLAYRVFQDMKDSNLMPDRETKELLVKSLWREEKRKEAAAVEESYEEENDNKNSSNVLRLALKGHVWTISSTDISRVYNLYRDCVLKTST
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g66631.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: SYA_PARDP
Sequence: MPSLNDVRSTFLNYFERNGHRVVESSPLVPRNDPTLMFTNSGMVQFKNLFTGVETRDYKRATTAQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKDGAIPFAWELLTKDFGIPKDKLLVTVYHTDDEAADIWKKVAGLSDDRIIRIPTSDNFWQMGPTGPCGPCTEIFYDHGEQIWGGPPGSADEDGDRFIEIWNLVFMQNEQFEDGTMRALDMQSIDTGMGLERIGALLQGKHDNYDTDLMRGLIEASAHATSADPDGPGKVHHRVIADHLRSTSFLIADGVMPSNEGRGYVLRRIMRRAMRHAHMLGAKDPVMHRLVPALVREMGAAYPELGRAQALIEETLKLEETRFKQTLDRGLRLLDDELAKLPEGANLPGEAAFKLYDTYGFPLDLTQDALREKGRAVDTAGFDSAMAEQKAKARAAWAGSGETKDAAIWFDIAEEHGATEFLGYDTEISEGQVLALVQDGAAVEEAGEGQQVQIVVNQTPFYGEAGGQVGDTGLIKTETGAARVTDTKKTGGVFIHIAEVTLGTIQRGQGAQLSVDHDRRSAIRANHSATHLLHEALRRALGEHVAQRGSLNAPDRLRFDFSHAKAMTPEELAQVEREVNDFIRQNSPVETRIMTPDDARALGAQALFGEKYGDEVRVVSMGELPGSGKGTGGQTYSLELCGGTHVARTGDIGMFALTSETASAAGIRRIEALTGQAAMDELRRVDGELNEIAGIVKAQAGDVVSKVRALADERKALANEVAQLKRQLAMGGGSEDKPREINGIKLIARRVEGVSGKELGPLVDEMKSRLGSGAVVVLAEADGKATVAAGVTPDLTGRISAVELVQTATAALGGKGGGGRPDRAQGGAPSLAAADSAISAVETLIGEKA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_CHRVO
Sequence: MAMPRYLTEPAFRHDYAPKTGVLLINLGTPDAPTAQALRPYLKQFLSDPRVIEIPRLPWWLILNGIILNTRPKQSAKKYASIWTKEGSPLLLHTRSQAKLLKGQLGEMGLHNLAVDYAMRYGNPSIESVIGKMREQGVERLLLLPLYPQYAASSSATALDEAFRVLSRLRNMPEVRTVRHFHDDPGYIAALAAQIRKHWQYGQRPDKLVMSFHGVPRFTRDKGDPYHCECQKTGRLLAEALQLRPDQYVISFQSRFGRTEWLKPYTSEVLEALGKAKTARVDVVCPGFVGDCLETLEEIAMEGKETFLSHGGGEFRYIPCLNEDPQWISSLAGIVRNNLAGWTEIRAEDSQQRAALAHDMGASA
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB28_BOVIN
Sequence: MSDSEEESLDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGSLNVTLQVWDIGGQTIGGKMLDKYIYGAQGVLLVYDVTNYQSFENLEDWYSVVKKVSEESETQPLVALVGNKIDLEHMRTVKPEKHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVVKADIVNYNQEPMSRTVNPPRSSMCAVQ
What are the official names of this protein?
Ras-related protein Rab-28.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium basal body. Note=Expressed in the basal body and ciliary rootlet of the photoreceptors.
Protein: RIBB_TOLAT
Sequence: MNQSLLTPFGNPFQRVEQALSALQQGNGVLVVDDEDRENEGDLIFSAEKMTPQQMALMIRECSGIVCLCLTEERIRQLALPMMVEHNTSANQTGFTVTIEAARGVTTGVSAQDRITTIRTAIADGAVASDLNRPGHVFPLRARAGGVLTRRGHTEATIDLMKLAGLKPYGVLCEVQNEDGSMARLPGIVEFANKHNMPVLCIEDLVAYLTENAKAAG
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: LIPA_MAGMM
Sequence: MISGVDPQTHLPSGKPRWLKVKAPTSPGYLKLKGMLRQGGLHTVCEEATCPNIGQCWHEGSAAFMILGDTCTRRCAFCNVKTGKPLPPNPDEPQQLALTAQRMELKHVVITSVDRDDLEDGGAGQFIACIQALRRVLPEASVEVLTPDFRHKQGALERLVAARPDVFNHNVETVPRLYANVRPVSSYAFSLEVLRRAKQLNPEGMTKSGIMLGLGEDEAEVLAVFADLRAAGVDYLTVGQYLRPSPAHHAVVRYWEPERFEALGQQALQLGFKRVSSAPLARSSFHASELHGVDNA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX3_OPICY
Sequence: SCKRECSGSKRQK
What are the official names of this protein?
Toxin OcyKTx3.
What are the subcellular locations of this protein?
Secreted.
Protein: ITC1_YEAST
Sequence: MVLYKRKPILLPDPKPLPLDLNVQVWHIEETGEWFSSYEEFLERFDFYTRHHFTCEITGTSCLTFFQALDSEETQFKYVEDRFPLKLREPVARFLHFNGIRRLDALVEKVYARFKNDFFPGEVVYLRKQKDSSTTSSNSQQSTPQPDDMVEINSVGNPGLPQYQYQRRYVIKEKVQFNATINPESREIVMPAHTKYMLIEEAASSNKSFIVDQGQIYRDRSTFTKHLIKCFFKITLQRASSKMGAPWCVKPEYLAMYGLTMEWPKDMLKYKEDEPVVARRSNSANVSSPESEKNKRQSKSSGKSNTSNDASNKKETKKKRKPTEVNDSENNSSEEDKKKGQNVTSETHSKKRKKEANEEPNTENVESVPTPANAEPQAVTITSIMDDLALPYQHPPNIFPNLTYYNEKLECISLGSTKLSRPFDSFGKLLQAYQFLNTFGSKICLSHFSLDQFITSLKCTDPYELKGEVVLVNIRTQTSKEQEIENNGLPMKNKAETTTEEDSENPSDWQRNSFIRDMIMKRNSDKVEYKIVHDDPASDDILDNINHNGSALLIEVFTALLRLFINEEGDWSCIVVENWIIDDKGVLMERKDERGEGEAKQKRNAHGYFLQDKEKIDNLKDTLKENATEVQKESDAKNETNSESDSKSDSDSEERDPKLEKCLNYRNVNWIERLTKRQFNNSYWLIILLGVLEDCRHLPMYTEFIDSFIEKIIPKDISATQLPKQLWRNFCRKLSFSDKVNALWILVDLVSHFSPDIKAAVDDSMELCGQIRSERFKVARELKTEAAVLSNLQGDLQAIQEKLNKTDENTPSADGADKKDDSESNSEPIDLIIIEKKQKLIEEQDKKVQALQSDKNFLDNCLFENDLQRLKPLGLDRYGNRYFWLDHNGVPFPQYPAGMNETPKSNNSLSYHSGRLLIQGPKASSAKFFLNVSDEQLSNWQKIRNSEGISEATREVFGISKTSSGSYNYVENGIEVELLDSNDRVNPLIELTPIQKKIMDETPSRLLLSPDQWYCIDKLEDLSRIMDWLDNWGRKEHDLLRQIRPIMERIKSSLSLRDHALSLTAFTKNEEKLLKELENNEFTENELNVDSMDVDDKNSGVKSEVDVQVDAEEKREAVIDEKLEVIADELMKLDDSSKTRNVLNRIQELEDQRDELLEQKKSIINSQRPGARILARSERKRTKISRGNKVNKQIEILTDLVNYRHFKAMEDVIAWKNVLANSIWGSSLRKNASGNKRSGVIETVDDKLKDIVGQTSRTVTPAPN
What is the function of this protein?
Functions as component of the ISW2 complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA.  The ISW2 complex is involved in coordinating transcriptional repression and in inheritance of telomeric silencing.  It is involved in repression of MAT a-specific genes, INO1, and early meiotic genes during mitotic growth dependent upon transcription factor UME6 and in a parallel pathway to the RPD3-SIN3 histone deacetylase complex.  ITC1 is required for nucleosome-stimulated ATPase activity and chromatin-remodeling activity of the complex.  Required for the repression of MATa a-specific genes.
What are the official names of this protein?
Imitation switch two complex protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS13_CAMLR
Sequence: MARIAGVDLPKKKRIEYGLTYIYGIGLHTSRKILDKTGISYDKRVHELSEDEAAAIRKEIQENYMVEGDLRKQVAMDIKALMDLGSFRGLRHRKGLPVRGQKTKTNARTRKGKRKTVGAKS
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: SYT_ECOL5
Sequence: MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NXNL2_MOUSE
Sequence: MVDVLGGRRLVTREGTVVEAEVALQNKVVALYFAAGRCSPSRDFTPLLCDFYTELVSEARRPAPFEVVFVSADGSAEEMLDFMRELHGSWLALPFHDPYRHELKKRYEITAIPKLVVIKQNGAVITNKGRKQIRERGLACFQNWVEAADVFQNFSG
What is the function of this protein?
May be involved in the maintenance of both the function and the viability of sensory neurons, including photoreceptors and olfactory neurons.  In the retina, isoform 1 may be required for rod function and isoform 2 for cone viability and function.
What are the official names of this protein?
Nucleoredoxin-like protein 2, Rod-derived cone viability factor 2, RdCVF2.
What is the protein family that this protein belongs to?
Belongs to the nucleoredoxin family.
Protein: D14_ORYSJ
Sequence: MLRSTHPPPSSPSSSSSGGGGGGGSSASSSSEKTMVGGGGGGGGGSGSAAPSGAKLLQILNVRVVGSGERVVVLSHGFGTDQSAWSRVLPYLTRDHRVVLYDLVCAGSVNPDHFDFRRYDNLDAYVDDLLAILDALRIPRCAFVGHSVSAMIGILASIRRPDLFAKLVLIGASPRFLNDSDYHGGFELEEIQQVFDAMGANYSAWATGYAPLAVGADVPAAVQEFSRTLFNMRPDISLHVCQTVFKTDLRGVLGMVRAPCVVVQTTRDVSVPASVAAYLKAHLGGRTTVEFLQTEGHLPHLSAPSLLAQVLRRALARY
What is the function of this protein?
Involved in strigolactone (SL) signaling pathway.  May function downstream of SL synthesis, as a component of hormone signaling or as an enzyme that participates in the conversion of SL to the bioactive form.  Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds (PubMed:19579033, PubMed:19542179, PubMed:23301669).  Strigolactone-dependent association of D14 with D3 and D53 (a repressor of SL signaling) triggers D53 ubiquitination and degradation (PubMed:24336200, PubMed:24616269).  Hydrolyzes the butenolide ring of SLs (PubMed:23381136, PubMed:24131983).  A reaction product D-OH is trapped in the cavity of D14, inducing the interaction with SLR1, and probably with other proteins such as D3 and D53 (PubMed:24131983).  Contributes to the negative regulation of gibberellin signaling (PubMed:24131983).
What are the official names of this protein?
Strigolactone esterase D14, Protein DWARF 14, Protein DWARF 88, Protein HIGH-TILLERING DWARF 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The interaction between D14 and SLR1 takes place in the nucleus (PubMed:24131983). The interaction between D14 and D3 takes place in the nucleus (PubMed:24616269).
Protein: CBIA_HALMA
Sequence: MEGFVLAGTSSGVGKTVATLATLTALEDAGYQPQPAKAGPDFIDPSHHEALVDTPSRTLDPWLAGEDGMRRTYWRGTGDICVVEGVMGLYDGTKTSTAAVAEGLDLPVVLVVDAKAGMESVAATALGFAQYADRIGVDIEVAGILAQRAHGGRHADGIRDALPEDLTYFGRIPPMSDLEIPDRHLGLHMGSEAGLDRDALSTAAETIDIERLVETARAPPEVATTERNTGDSPADRRVAVAQDSAFCFIYPSVLERLRSEASVEPFSPVAGDSVPDADAIYLPGGYPELHGESLETGGTLDEIAVRAADGVPVYGECGGLMALSESLTTTDGDTYEMAGVLPADIEMQDRYQALDHVELEARADTVAATSGAHRRGHEFHYSAATLGSDASFAFDMVRGDGIDGEHDGLTEYSTIGTYCHCHGESGAFDRLLAVPSKDI
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: Y5079_MYCMM
Sequence: MAGNSQRRGAIRKSGTKKGTSVGSGGQRRRGLEGRGPTPPAHMRPNHPAAKRAKAQQRRPARGRTDETETVLGRNPVLECLRAGVPSTALYVALGVEADERLTESVSRAADSGIPILEVPRTDLDRMTANHLHQGIALQVPPYNYAHPDDLLAAALDTPPALLVALDNISDPRNLGAIVRSVAAFGGHGVLIPQRRSASVTAVAWRTSAGAAARMPVARATNLTRALKDWADRGVRVVGLDAGGDTAIDDLDGSDPIVVVVGSEGKGLSRLVRQTCDEVVSVPMAGPTESLNASVAAGVVLAEIARQRRT
What are the official names of this protein?
Uncharacterized tRNA/rRNA methyltransferase MMAR_5079.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: VAX1_RAT
Sequence: MFGKTDKMDVRCHSDTEAARVSKNAHKESREIKGAEGSLPAAFLKEPQGAFSASGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAATAPGPAGAASQHPPAVGGAPGPGPAGPGGLHAGAPTASHGLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD
What is the function of this protein?
Transcription factor that may function in dorsoventral specification of the forebrain.  Required for axon guidance and major tract formation in the developing forebrain.  May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk (By similarity).
What are the official names of this protein?
Ventral anterior homeobox 1.
What is the protein family that this protein belongs to?
Belongs to the EMX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CP2CE_RABIT
Sequence: MDPVVVLVLCLSCLLLLSLWKQSHGGGKLPPGPTPLPILGNILQIDFKDISKSLQNLSKVYGNVFTVYMGMKPTVVMYGYEAVKEALVDLGEEFSGRNLSPINKKVNKGLGVIFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILGAAPCNVICSVIFQNRFDYKDETFLNLMGKFNENFRILNSPWLQVCNIFPILMDYLPGTHKTVFENFDYVRNFVLEKTKEHQESLDINNPRDFIDCFLIKMKQEKHNQQSEFTIENLMATVTDVFAAGTETTSTTLRYGLLLLMKHPEVTAKVQEEIERVIGRHRSPCMQDRSRMPYTDATVHEIQRYINLVPNNVPHATTCNVKFRNYFIPKGTAVLTSLTSVLHDNQEFLKPDKFDPGHFLDASGNFKKSDYFMPFSTGKRVCMGEALARMELFLFLTAILQNFTLKPLVDPKDIDTTPLVSGARSCATLYQLSFIPA
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2C14, CYPIIC14, Cytochrome P450 PHP3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: ALF2_PARBA
Sequence: MGVKDLLSRKTGVIVGDDVLRLFQHAQENVFAIPAIMVTSSSTGSALEAARDKSPIVLQTSNGAAYFAGKGKGVSNDGQSVAGSIAIAAAHYIRSQAPAYGIPVVLHTDHCAKKLLPWLDGMLDADECYSKLHNEPLFSSHMIDLSEESVEWNIETTAKYLKRAAPMKQWLEMEIGITGGEEDGVNNESVDNNSLYTQPEDIYTIYKTLSAISPYFSIAAGFGNVHGVYRGDIALRPLLRHLHNAKYDEQLKCLQDPLGFFVFHGGSGSSHQPATSITSEFAAKGRVDLEKVAYLPGTSSLVIAPKDYLMSPYGIPVVLHTDHCKYFDPRVQIREGLKHMSARVQEAKDDFNDSNQAKKLLPW
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase 2, FBP aldolase 2, FBPA 2, Fructose-1,6-bisphosphate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: RL1_THENN
Sequence: MPKHSKRYLEAKKLVDRTKYYDLDEAVELVKKTATAKFDETIELHIQTGIDYRKPDQHIRGTIVLPHGTGKEVKVLVFARGEKAKEAQEAGADYVGAEDLVEKIEKEGFLDFDVAIATPDMMRVIGRLGKILGPRGLMPSPKSGTVTNEVAEAVKEFKKGRIEVRTDKTGNIHIPVGKKSFDNEKIKENVISAIKQIMQMKPAGVKGQFIKKAVLASTMGPGIKLNLQSILNE
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RNPA_ALISL
Sequence: MNYDFSRELRLLTPEDYKSVFKQAHRAGSPHFTILARENSLSHPRLGLAVPKKQIKTAVGRNKFKRITRESFRNKQHSLPAKDFVVIAKKSAQELSNEDFNKLLDKLWHRLSRPSRG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.