PharMolix/UniProtQA huggingface dataset:
Protein: CPLN2_XENTR
Sequence: MALAEAPRPGPLMDPEWHGSPEGKEYLGCILRKKKRKFFGLIERPVLSPQLPADIASYKLFVCGRSGAGKTSFIAKLAGLEVPSMHHETTGIQTTCVYWPVRPTHSARPVIFRFQFWDCGEGALRKFDHILPACKEMADAVLFLFSFTDRSSFEDVPALISRTLGQEEDVARVVIGTKLDQYTHTDVTENDLRDFQRTWQLPVMRVRSVNGPRVAEGRGLDGRVGLVECAPVLNGLAEILWRRDQVIAGLVGGAD
What is the function of this protein?
Potential effector of the planar cell polarity signaling pathway.  Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes.  Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia.  More generally involved in exocytosis in secretory cells (By similarity).
What are the official names of this protein?
Ciliogenesis and planar polarity effector 2, REM2- and Rab-like small GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: RL10A_CHLRE
Sequence: MSKISNDVLRESVSALVEGAKTKPRKFQETVELQIGLKNYDPQKDKRFSGSVRLPFVPRPRMRVRAGDVKHCEQAGAIGVDAKGVEDLKKLNKNKKLVKKLAQAYHAFLASDSVIKQIPRLLGPGLNKAGKFPAPINKNLEEMVLDTKCSIKFQLKKVLCMGVAVANVGMTEGEIRTNIMYAINFLVSLLKKNWQNVRCLYIKSTMGKPIRIY
What are the official names of this protein?
60S ribosomal protein L10a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: DUS3_PICGU
Sequence: MTTETEKRALEDDTVESKRIKYDKGIAPIKPEFIVENPSVPADDRYVNDDDAEAGDRNGEEKGKKKKRGQNKKRDMRQQHEEVRLCSSLLDPSNPGTCRFGPEHCRSTHDVTTYLAAKAPDIDGVCPVFKSIGYCPAGLKCRWLNSHYEDGKLKRDQSQIDAYASSGQGEVNKISTEAKLALQKKKYLFEVSDNVIKYLDSQVQSDENIAKREEAKENNASYVEAPFKIAEKKKLDLRGAKIVSPLTTVGNLPYRRLMKTLGADVTYSEMALSLPLLQATNSEWALPKAHSSEYPGFGVQIATSKHWAAAKAAEVIYKETTHVSELNLNCGCPIDLLYRQGQGSALMEQPARLLRILKGMNASSGDIPVTVKIRTGTKDNKNTAKSLVERVLAENDVAAITLHGRSRQQRYTKDADWEYIKEVGAVVTEWNNKKEEDKESSETNRTNFVGNGDVFTHEDWYNAVNTEGVDSVMVARGALIKPWIFEEVEAQQYLDKSATERLDILRKFADFSLEHWGSDEYGVGLSRRFMCEFLSFTHRYIPVGILERLPPKINQRPPQWRGRNELETLLGSTDYKDWIKITEMFYGKTGDNFTFIPKHKSNAYESG
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MAGI2_MOUSE
Sequence: MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKLVSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGSVDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEEFMELEKSGALLESGTYEDNYYGTPKPPAEPAPLLNVTDQILPGATPSAEGKRKRNKSVTNMEKASIEPPEEEEEERPVVNGNGVVITPESSEHEDKSAGASGETPSQPYPAPVYSQPEELKDQMDDTKPTKPEENEDSDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDPIYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGAKPLQAPGFREKPLFTRDASQLKGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQSVPDITDRPPHSLHSMPADGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPVGSETSLIIHRGGFFSPWKTPKPMMDRWENQGSPQTSLSAPAVPQNLPFPPALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQHSPLAQQSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGGDYSQPPPLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYGMVPSSLSMCMKSDKHGSPYFYLLGHPKDTTNPTPGVLPLPPPQACRK
What is the function of this protein?
Seems to act as a scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins (By similarity).  Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth (By similarity).  May play a role in regulating activin-mediated signaling in neuronal cells (PubMed:10681527).  Enhances the ability of PTEN to suppress AKT1 activation (By similarity).  Plays a role in receptor-mediated clathrin-dependent endocytosis which is required for ciliogenesis (PubMed:24608321).
What are the official names of this protein?
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, Activin receptor-interacting protein 1, Acvrip1, Atrophin-1-interacting protein 1, AIP-1, Membrane-associated guanylate kinase inverted 2, MAGI-2.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Cytoplasm. Late endosome. Synapse, synaptosome. Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Note=Localized diffusely in the cytoplasm before nerve growth factor (NGF) stimulation. Recruited to late endosomes after NGF stimulation. Membrane-associated in synaptosomes (By similarity).
Protein: PLSB_ALTMD
Sequence: MSWMRKALLSVFHYPVKLLVKAHSIPVNVETELGIDKSKPIVYLLPTNSVTDQLSLRMSTQALDLPSPTKTLTLAGREYSSTLFLRKTQPLFRSSAKDTGIEEVFTDLFHLHRDHENLDLQVVPVYVTWGRAPGRGNPGLSDLIADKAAPSWLRKLFIVLFLGRDNFINYSKAVSARAMSNQHGSDQSIAHKLVRVASTHFQRKRQSMTGPTLLERQELNNSVLGSDAVRRAIAEESRSKKVSHDKAKACAQSYITEIAADYREGLIRFGDRLLTRIWNKIYNGISVGHAERIRELAANGHEIIYVPCHRSHMDYLLLTYVIYHEGMVTPHIAAGINLNFWPVGKMFRRGGAFFLRRSFAGNKLYTAVFREYLELLFNKGYSVKYYPEGGRSRTGRLIPPKTGMLAITIQAMLKGVNRPVSIVPVYIGYENVMEVKSYLNELKGSKKKKESNLQVFSAIRKLKNYGHGYVNFGEPIALNQFLESHVPNWRDCKDAEPEKKPAWLTPAVNELANNVMTRINRAAALNGMALTSLCLLSSKTQTMSEAELKQSIGDFMDLFKAVPFSDDATIPDSTAEALLRDTLKLGRFDIKEDDYGRLISPQPKSAVYLTYYRNNILHLFAIPGLVMASVFAKKGTTKNDILQLIAALYPLLQKELFLHLTQDEALAHTDALVTALLNNGLLRQKDKELLPPDAHCKQFHSAWLLSRCMQETLQRYAVVLTILDKEKVISRGALERESKQVAERLSALYGLSSPEFYDKNVLSSFIGALKENHWLDSEKDGSLKYSEECEALRQDVMALIWPEMMQHLENVALNGQTN
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YJBA_SCHPO
Sequence: MLFKISFLALIASALAMSINSPTNGDTWQTNGEEQITWNVVSTDEPSAALYLTNFAVYPTVTQYLDTVDTSTGSYTTNTTNWPTGQGFQINMAYPGRPEQIYAQSQQFNIVEGAASSSSSSSSSSSSLVSSTTSSSSSATPSTTSSSSSSSSSSSSSSSKSSSSSSKSSSRSSSRTTSHRTTSHKSSSYRPTVFPYTTISHYNITNATNGTYCNGTNGTNFTCIVNASNATNSTFWLNGTNSTNGTNSTNSTSTTSHSLTKLPTSSKSLTTSKTTASGHITKGVMEALSTNDTTNTTDDATNTTSDSSSSSSASASSSSSSSSAASLVSQPVGISAVIAFFAVALSLTL
What are the official names of this protein?
Uncharacterized protein C553.10.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Localizes at the cell surface.
Protein: URED_LEPCP
Sequence: MSWHGHLQLHYRHDPNEDRTVAHDRHHGPLRVLQRLYPEGPSICHHVLVHPPGGIVGGDTLEVDLDLAPGSHALITTPGATRYYRSAGEVARQQVRARLAEGSRLEWLPLETIAYDACIAENSLRFEIAPGAMMMGWDLLALGLPAAGKPWQRGSYLQQLELPGIWLERARIDAADARLLDSPLGWAGQRVLGTFWLAGGDALPKGLSDALIESARALIGDSALAATAGVSAPHANTVVLRVLAPRVEPAMHLLGAIRAAWRSIAWHLDPCVPRIWRT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPP_GEOKA
Sequence: MTNKNDGKDMRKNAPKGDNPGQPEPLDGSKKVKNRNHTRQKHNTSHDM
What are the official names of this protein?
Small, acid-soluble spore protein P, SASP P.
What is the protein family that this protein belongs to?
Belongs to the SspP family.
What are the subcellular locations of this protein?
Spore core.
Protein: VP4_ROTP3
Sequence: MASLIYRQLLTNSYTVNLSDEIQEIGSAKSKNVTINPGPFAQTGYAPVNWGAGETNDSTTVEPLLDGPYRPTTFNPPTSYWVLLAPTVEGVVIQGTNNIDRWLATILIEPNVQTTNRIYNLFGQQVTLSVENTSQTQWKFIDVSKTTPTGSYTQHGPLFSTPKLYAVMKFSGRIYTYNGTTPNATTGYYSTTNYDTVNMTLFCDFYIIPRNQEEKCTEYINHGLPPIQNTRNVVPVSLSAREVVHTRAQVNEDIVVSKTSLWKEMQYNRDITIRFKFDRTIIKAGGLGYKWSEISFKPITYQYTYTRDGEQITAHTTCSVNGVNNFSYNGGSLPTDFAISRYEVIKENSFVYIDYWDDSQAFRNMVYVRSLAANLNTVTCTGGSYTFALPLGNYPVMTGGTVSLHPAGVTLSTQFTDFVSLNSLRFRFRLTVGEPSFSITRTRVSRLYGLPAANPNNQREYYEISGRFSLISLVPSNDDYQTPIMNSVTVRQDLERQLGELRDEFNSLSQQIAMSQLIDLALLPLDMFSMFSGIKSTIDAAKSMATNVMKRFKRSNLASSVSTLTDAMSDAASSVSRSSSIRSIGSSVSAWTEVSTSITDISTTVDTVSTQTATIAKRLRLKEIATQTDGMNFDDISAAVLKTKIDKSVQITPNTLPDIVTEASEKFIPNRTYRVINNDEVFEAGMDGKFFAYRVDTFDEIPFDVQKFADLVTDSPVISAIIDLKTLKNLKDNYGISKQQAFDLLRSDPKVLREFINQNNPIIRNRIENLIMQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: NDHI_SPIOL
Sequence: MFPMVTGFINYGQQTIRAARYIGQSFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRACPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPISITDDYTIRTILNSPQTKEKACD
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: FTSZ_STRP2
Sequence: MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAANTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFITAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVDTLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTVMANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEAEEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATNYRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSVVSPVERFEAPISQDEDELDTPPFFKNR
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: UREE_ECO57
Sequence: MLYLTRRVETPAQTTASVTLPVDMRVKSRIKVTLNDGRQAGLLLPRGLLLRDGDILSNENGDEFIKVIAADEAVSVVRCADPFMLAKACWHLGNRHVPLQIMPGELRYHHDHVLDDMLRQFGLDVDFAHLPFEPEAGAYASKSHAHNHDQEHSH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_RALPJ
Sequence: MQNQKIRIRLKAFDYRLIDQSAAEIVETAKRTGAIVKGPVPLPTRIQRFDVLRSPHVNKTSRDQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: URE1_PSEPK
Sequence: MSHISRQAYADMFGPTVGDRVRLADTALWVEVEKDFTIYGEEVKFGGGKVIRDGMGQGQMLAAEAMDLVLTNALIIDHWGIVKADIGIKHGRIAVIGKAGNPDVQPGVNVPVGPGTEVIAAEGKIVTAGGVDSHIHFICPQQVDEALNSGVTTFIGGGTGPATGTNATTCTPGPWYLARMLQAADSLPINIGLLGKGNASRPDALREQIAAGAVGLKLHEDWGSTPAAIDCCLGVAEEMDIQVAIHTDTLNESGCIEDTLAAIGDRTIHTFHTEGAGGGHAPDIIRAAGQANVLPSSTNPTLPYTINTVDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDMGAFAMTSSDSQAMGRVGEVVLRTWQVAHQMKLRRGPLAPDTPYSDNFRVKRYIAKYTINPALTHGIGHEVGSVEVGKLADLVLWSPAFFAVKPALVLKGGMIVTAPMGDINGSIPTPQPVHYRPMFGALGAARHATRMTFLPQAAMDRGLAEELNLRSLIGVVNGCRRVRKPDMVHNTLQPLIEVDAQTYQVRADGELLVCEPASELPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_LEPCP
Sequence: MTPFLRQQLSRQALRLAEIDAALADPKVCSQIGTLRSLNREHARVSALVDRWQRYEQREQDLAGAQELLDEPEMAELARAEIGAAQADLDRLDSELLTALMPRDADDDRNAFVEIRAGTGGEESALFAADLARMYLRHAERRGWKTELMSESVSDLGGYKDVVLHIIGDAVFEALKYESGGHRVQRVPATEAQGRIHTSACTVAVLAEADEAEEVSLNPAELRIDTYRASGAGGQHINKTDSAVRVTHLPTGLVAECQDDRSQHRNKARALAVLAARLRDRVRQEQAAKDAAARKSLIGSGDRSDRIRTYNFPQGRLTDHRINLTLYKLGAVLEGDLDEVIGALQAAHAAEQLAELETQA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1BG_EQUAS
Sequence: AVVFDPQPALWAEADTQLEP
What are the official names of this protein?
Alpha-1B-glycoprotein, Alpha-1-B glycoprotein, Postalbumin.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_METFK
Sequence: MLLELARWLAQDIRGFNVFNYITLRAVLATLTALTISFLVGPKLIRKLTEYKVGQSVRDDGPQTHLVKAGTPTMGGALILIAIVISTLLWADLSNRFVWVVLITTLGFGVIGWVDDWRKVVYRNPKGLSAKAKYFWQSLIGAGVAAYLFHTATVPAETELIVPFFKHLVLPLGAVSFIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVMVASALAVFAYVAGHLYFSKYLGVPYVPGAGELTVFCAAIGGAGLGFLWFNAYPAEVFMGDVGALALGAALGTVAVIVRQEIVLFIMGGVFVMETISVMLQVGSFKLTGKRIFRMAPLHHHYELKGWKETQVVVRFWIITMMLVLVGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLOB_ANTMA
Sequence: MGRGKIEIKRIENSSNRQVTYSKRRNGIMKKAKEISVLCDAHVSVIIFASSGKMHEFCSPSTTLVDMLDHYHKLSGKRLWDPKHEHLDNEINRVKKENDSMQIELRHLKGEDITTLNYKELMVLEDALENGTSALKNKQMEFVRMMRKHNEMVEEENQSLQFKLRQMHLDPMNDNVMESQAVYDHHHHQNIADYEAQMPFAFRVQPMQPNLQERF
What is the function of this protein?
Transcription factor involved in the genetic control of flower development.  Acts in conjunction with DEFICIENS (defA).
What are the official names of this protein?
Floral homeotic protein GLOBOSA.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECR_FLAPJ
Sequence: MEFSSKLLEKAVNEMAQLPGIGKRTALRLVLYLLKQPKDRTDFLAQSLLTMREGIIFCENCHNISDVAVCEICSNKNRNHQIVCVVEDVRDVMAIENTGQFRGVYHVLGGKISPIDGVGPSQLNISSLVEKVKSGSVSEIIFALSSTMEGDTTNFYIYKQIKDCEIITSSIARGISVGDELEYADEVTLGRSILNRIPFENSFKNN
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RS11_LEPBL
Sequence: MADDKKSVKKEKKVKKKEKKIVPRGKVYITASFNNTIVTITDMAGNTISWSTSGAMGFRGSKKSTPYAAQIAAGNAAEKAMDSAGLQEVDVMVSGPGIGRESAIRSLVARGLNIKMIKDVTPLPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SYT11_HUMAN
Sequence: MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLKGISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSEY
What is the function of this protein?
Synaptotagmin family member involved in vesicular and membrane trafficking which does not bind Ca(2+).  Inhibits clathrin-mediated and bulk endocytosis, functions to ensure precision in vesicle retrieval.  Plays an important role in dopamine transmission by regulating endocytosis and the vesicle-recycling process.  Essential component of a neuronal vesicular trafficking pathway that differs from the synaptic vesicle trafficking pathway but is crucial for development and synaptic plasticity.  In macrophages and microglia, inhibits the conventional cytokine secretion, of at least IL6 and TNF, and phagocytosis.  In astrocytes, regulates lysosome exocytosis, mechanism required for the repair of injured astrocyte cell membrane (By similarity).  Required for the ATP13A2-mediated regulation of the autophagy-lysosome pathway (PubMed:27278822).
What are the official names of this protein?
Synaptotagmin-11, Synaptotagmin XI, SytXI.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass membrane protein. Perikaryon. Golgi apparatus, trans-Golgi network membrane; Single-pass membrane protein. Recycling endosome membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein. Cytoplasmic vesicle, phagosome. Cell projection, axon. Cell projection, dendrite. Postsynaptic density. Recycling endosome membrane; Single-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass membrane protein. Perikaryon. Note=Localized in vesicles that travels in axonal and dendritic shafts in both anterograde and retrograde directions. In macrophages and microglia, recruited in phagosomes at early stages of phagocytosis (By similarity). Found in the core of the Lewy bodies in the brain of sporadic Parkinson disease patients (PubMed:12925569).
Protein: PILR2_ARATH
Sequence: MKETNFGEKTRVLVVGGTGSLGRRIVSACLAEGHETYVLQRPEIGVDIEKVQLLLSFKRLGAHLVEGSFSDHQSLVSAVKQVDVVVSAMSGVHFRTHNIPVQLKLVAAIKEAGNVKRFLPSEFGMDPSRMGHAMPPGSETFDQKMEIRNAIKAAGISHTYLVGACFAAYFGGNLSQMGTLFPPKNKVDIYGDGNVKVVFVDEDDMAKYTAKTLNDPRTLNKTVYVRPTDNILTQMELVQIWEKLTEKELEKTYVSGNDFLADIEDKEISHQAGLGHFYHIYYEGCLTDHEVGDDEEATKLYPDVKYKRMDEYLKIFV
What is the function of this protein?
Reductase involved in lignan biosynthesis (PubMed:18347017).  Unlike conventional pinoresinol reductases that can reduce both pinoresinol and lariciresinol, PRR2 shows a strict substrate selectivity for (-)-pinoresinol (PubMed:18347017).  No activity with (+)-pinoresinol or lariciresinol (PubMed:18347017).  Abstracts the 4R-hydride from the NADPH cofactor during catalysis (PubMed:18347017).
What are the official names of this protein?
Pinoresinol reductase 2, AtPrR2, (-)-pinoresinol reductase, Pinoresinol-lariciresinol reductase 2, AtPLR2.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: LGT_BURM7
Sequence: MIIHPNFDPVAIHLGPLAVRWYGLMYLVGFILAIVVGRLRLKLPHVAAQGWSAKDIDDMMFYGVLGVVLGGRLGYVLFYKAGYYFSHPLDIFRVWEGGMSFHGGFLGVTLAMALFAWQRKRHWLEVTDFVAPMVPTGLAAGRLGNFINGELWGRVTSPDAPWAMLFPGASRDDAAWLAAHQDIAAKWNLNEVFLSHQMLPRHPSQLYEIALEGIALFFVLWFFSRKPRPMGAISALFLIGYGAARFTVEFAREPDDFLGLLTFGLSMGQWLSLPMIVAGVLMMIWAYRRGGVAKQA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEF_SALNS
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGNPFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVEKLDRLNARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.