PharMolix/UniProtQA huggingface dataset:
Protein: ATPA_PRIM1
Sequence: MSIKAEEISALIKQQIENYQSEIKVSDVGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGMAQNLEENNVGIIILGPYTEIREGDEVRRTGRIMEVPVGEQLIGRVVNSLGQPVDGLGPVETTKTRPIEGAAPGVMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTSVAIDTILNQKDQDMVCIYVAIGQKESTVRNVVETLRKHGALDYTIVVTASASQPAPLLFLAPYAGVTMGEEFMYNGKHVLVIYDDLTKQASAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYRELESFAQFGSDLDQATQAKLNRGARTVEILKQGLHKPLRVEKQVAVLYALTKGFLDDVPVSDITRFEDEYLTWLESNRKEVLESIRTTGGLPEAGLFESALEEFKKTFIASE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: 3S1CB_NAJNA
Sequence: METLLLTLLVVTIVCLDLGYTLECHNQQSSQTPTTTGCSGGETNCYKKRWRDHRGYRTERGCGCPSVKNGIEINCCTTDRCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Cobrotoxin homolog, Short neurotoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CSN5_ASPFU
Sequence: MQAAQQSWELENTISLIDPQRDALYRYDEETHKALSAARPWAKDPHYFKSIRISAVALIKMTMHARSGGSLEVMGLMQGYILPETFVVTDAFRLPVEGTETRVNAQEEANEYMVSYLQSCRDAGRMENAVGWYHSHPGYGCWLSGIDVTTQDMQQLGGPFVAVVIDPERTISAGKVDIGAFRTFPKDYTPPKEGNEDEDYQTIPLSKAEDFGAYAHQYYSLEVSFFKSSLDTELLSQLWNKYWVATLSQSPLFTTRDYGSRQMMDLSQKVRRAARGIESSGSRGGATTPKDQQLEKIVRDGQRIVSEEVKGLLAAEVKMKLFQGIGEGTQTGAS
What is the function of this protein?
Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
What are the official names of this protein?
COP9 signalosome complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL11_CERS4
Sequence: MAKKIIGSLKLQVKAGQANPSPPVGPALGQRGLNIMAFVKEFNAKSADLEPGTPTPVIITYYQDKSFSLELKTPPASFMLKKAAGLAPVGKRNRPKGSTKPGREVAGSVTVAQIRKIAEAKMKDLNANDVEAAMQIILGSAKSCGIEVKG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: ENSA_XENTR
Sequence: MSDKYIGDSHLEETGEEKQDSQEKEAVTPEKAEEQKLKAKYPNLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPCAGPDKNLVTGDHIPTPQDLPQRKSSLVTSKLAGHVEDLHQV
What is the function of this protein?
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.  When phosphorylated at Ser-67 during mitosis, specifically interacts with ppp2r2d (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity).
What are the official names of this protein?
Alpha-endosulfine.
What is the protein family that this protein belongs to?
Belongs to the endosulfine family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_XANC8
Sequence: MDIKQLREKSADELKAHLTDLRKEQFSLRMQQVTGQLPKTHETRRVRREIARVKHLLGSTQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CYB_SUSCE
Sequence: MTNIRKSHPLMKIINNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLFIHVGRGMYYGSYMFRETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIITALATVHLLFLHETGSNNPTGISSDMDKIPFHPYYTIKDILGALFMMLILLILVLFSPDLLGDPDNYTPANPLSTPTHIKPEWYFLFAYAILRSIPNKLGGVLALVASILILILMRMLHTSKQRSMMFRPLSQCLFWMLVADLIALTWIGGQAVEHPFIIIGQLASILNFLIILVLMPMPSIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1356_AQUAE
Sequence: MGKVIQFPFGEEPEKKEEKELKTEPLTEEDFNQVIEVFKKDLKTLYPSQVKDILGVIGLGEKYGDEKFVVGLLMWEHYKHSHPLVSSFVAVLKGDKLEKISFLEAKNNYWDWKLMVKTYKDKFHTEELMRGLFELKERFEKGEI
What are the official names of this protein?
Uncharacterized protein aq_1356.
Protein: RS18_XANOR
Sequence: MSKFFRRRKFCKFTAEGVKEIDYKDLNTLRQYLTENGKIVPSRVTGTKSKYQRQLATAVKRSRFLALIPYTDNHDV
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HIS8_BDEBA
Sequence: MKISPEILNLVPYKPGKPISETQREYGLTTVYKLASNENPLGPSPKAMAAVKQALDHQHLYPDPSHYELLQTLSKEWGFPTKQLAIGNGSDELIDLLCRIYCEHHDGVLTSAAAFNAYEVSAPANRAVIHKVPMAEGYRFDLPAIADYFLKHPEKNIRLIFVSNPNNPTGTYATKAEVEAFLQKVGNRDDVMIIFDEAYNEFVRAKDYASAQGYMGQYKNLIVLRTFSKIYGLAGFRLGAMIAPPEVVEVFNRVRKPFNVNDLAQVAANAALQDKEFIERSQQICWKGLDYFYKKLEELGLPYIPSQGNFVMFDTLRDAAKVNEALLRRGIIMRPLLNYGFKTHLRLSVGRDHENEAAMVALAEVLKEITPL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: HMB4_TRIGR
Sequence: INIFMKKNCKCISFFIFFSIFFCRGREAEERGHANWLSATSGRKKRCPYTKFQTLELEKEFLFNMYLTRDRRLEIARLLSLTERQVKIWFQNRRMKMKKQNRAQNYP
What are the official names of this protein?
Homeobox protein HB4.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL28_CUPTR
Sequence: MARVCQVTGKAPMVGNNVSHANNKTKRRFLPNLQNRRFFVESENRWVSLRVSNAGLRLIDKKGIDSVLADLRARGEV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DEFI_PROTE
Sequence: MKFFMVFVVTFCLAVCFVSQSLAIPADAANDAHFVDGVQALKEIEPELHGRYKRATCDLLSGTGINHSACAAHCLLRGNRGGYCNGKGVCVCRN
What is the function of this protein?
Responsible for the anti Gram-positive activity of immune hemolymph of P. terraenovae.
What are the official names of this protein?
Phormicin, Insect defensin A/B.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS1_PYRIL
Sequence: MLLAIPSKGRLQEPTLRLLEAVGIKPLASDERALVLPTSWNDVNIIKARPEDIPYLVDSGRIWAGITGHDYIIESGSNVVEVLDLEFGKGKLVVAVPKTSGIKSIDELPPGARVATKFVNIAYNYFAELGKRVRIVRVAGSVEILPQLGIADAILDVMATGTTLEIHGLTPIATVLETSARLIVHPNYVNHELTKKLVTFIKGYYAAQGRKMIFLNVPATKLEDVLSILPAMEAPSVTKLAKGDVYEVFSVVPEDILPDLVMKLKNAGAKDIVVTSIEKLIS
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y954_AROAE
Sequence: MDWLREAADGSLVLSLHVQPGAKKTEFVGPHGEAMKLRLAAPPVDGKANAALTVFLAAFCGVGRSAVSLLSGETSRAKRVRIEGAGSEALARLRALG
What are the official names of this protein?
UPF0235 protein AZOSEA09540.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: NPR1_MALHU
Sequence: MAHSAEPSSSLSFTSSPHLSNGSISHNLSCSGSESVPSLEVISLSKLSSSLEQLLIDPGCDYSDADIVVEGIPVGVHRCILASRSGFFRELFKREKGSSGKEDRPKYCMSDFLPYGDVGYEAFLVFLSYVYTGKLKPSPVEVSTCVHNVCAHDACRPAINFVVELMYAASIFQMPDLVSIFERRLLNFVGKALSDNVVPILLVAFHCQLNQLIDQCVDRVARSDIDDISLEKGLPDEVVKKIKILRRNYQQDSDPNLPPADPLHEKRIRRIHKALDSDDVELVKLLLTESNITLDEANALHYAAAYCDPKVVTEVLALGLADVNLRNSRGYTALHIAVMRKEPSIIVLLLTKGARASELTSDGQSAVSICRRLTRPKDYHSKTEQGQEANKDRICIDVLEREMRRNPMAGDASISSQIMPDDLHMELLNLENRVALARLFFPAEAKLAMVIAHAETSEFAAPSSSKGSSGNLMEVDLNETPTVQNKRLHSRLEALMKTVRLGRCYFPHCSEVLDKFIDDDLPHLFYLEPGSSDEQKVKRRRFMELKEEVQKAFDKDKAECNLSGLSSSSSTTSPEKIGANQKVREP
What is the function of this protein?
Probable component of the salicylic acid (SA) defense signaling pathway and pathogen-induced systemic acquired resistance (SAR) (Probable).  May be involved in disease resistance against fungal pathogens (Probable).  May be involved in tolerance to salt and osmotic stresses (PubMed:24407603).
What are the official names of this protein?
BTB/POZ domain and ankyrin repeat-containing protein NPR1, MhNPR1, NPR1 homolog.
Protein: SECB_VIBPA
Sequence: MAEAAPQEAQQNFAIQRIFLKDVSFEAPNSPVIFQKEWNPDVKLDLDTQSRELGEGVYEVVLRLTVTVKNEEETAFLCEVQQGGIFTAEQMEAGQLAHCLGAFCPNILFPYARETISSLVVKGTFPQLNLAPVNFDALFMNYLQQQAQQGEAQA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRPS_PSEPU
Sequence: MNQSDENVGKAGGIQVIARAASIMRALGSHPHGLSLAAIAQLVGLPRSTVQRIINALEEEFLVEALGPAGGFRLGPALGQLINQAQSDILSLVKPYLRSLAEELEESVCLASLAGDKIYVLDRIVSERELRVVFPIGINVPAAATAAGKVLLAALPDETLQAALGEQLPVFTSNTLRRKALVKQLSEVRQSGFASDLDEHIDGVCSFATLLDTYLGYYSLAVVMPSSRASKQSDLIKKALLQSKQNIERAIGRASKKAP
What is the function of this protein?
In conjunction with SrpR represses the srpABC operon.
What are the official names of this protein?
HTH-type transcriptional regulator SrpS, Solvent efflux pump srpABC operon corepressor.
Protein: TSAD_SHEPA
Sequence: MRVLGIETSCDETGIAVYDDKKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALADAGMTIEDIDGIAYTKGPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPMLEDDVPEFPFLALLVSGGHSMIVGVEGIGRYTVLGESVDDAAGEAFDKTAKLMGLDYPGGPRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFEEAVVDTLAIKCKRALKQTGYKNLVIAGGVSANTRLRSSLAEMMQGLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQVEGLEVKGQPRWPLDTLEPVD
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_DESHD
Sequence: MRVGVLAVQGAFIEHEKILQNLGVECLELRNGKDARQDVEGLILPGGESTTQGKLLRELDMFEPLREKIVAGLPVLATCAGLILLAEELANDSARYFATLPVRVKRNAYGRQLGSFYTEEQFGDLGKVPMTFIRAPYIESVGEDVEILAKVNGDIVGVRYKNQIGLSFHPELNGDRRIHQMFLDSISGGKSFPCTQKAV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SRB12_CAEEL
Sequence: MSEANLTECELAYQLTYHPFYMIAQFWSFFVSLLAMPSLIFFMVEKVFKLPFHGNLKFLLVSYFIGTFLFASIICFTFGYHFFVPFFVTSNCDLIINATLFKYGHMIALIFMTIPMILPTAFTVERFVALKMAHSYEHVRTLLGPVLVLVVIAIDSMFLYDIYGQEKFDKPFINFILVPATSALQFNSFLWYMLYLKITNFICNLILLFIHKILHQSSRYRRKNVSLSVKYEMQEISQSSRFTLIVTFTHLLFFGWYVSTILLIRTVGPDFFRGFINYTVMRGVYCATPTYNLVIVFIGFKALNHLNFKRNNKVQSTIQIKSTGQEGAENYDNAISNYWDSVYTMNKSKL
What is the function of this protein?
G-protein coupled receptor (Probable).  Plays a role in the navigational capacity of sperm and promotes the targeting of sperm derived from males to the fertilization site in the uterus of hermaphrodites (PubMed:28662030).
What are the official names of this protein?
Serpentine receptor class beta-12, Protein srb-12.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srb family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite.
Protein: RS5_CHLPB
Sequence: MAKRTANNIKPGELNLKEKLVHINRTAKVVKGGKRFGFNAIVVVGDKEGHVGFGLGKANEVQDAIAKGVEDGKKNVIKVPIVKGTIPHQIIARYGSAKVMMKPATPGTGLIAGGAVRAVLEMAGIHDILAKSLGSSNPHNVVKAAISGLESISDAYDVAERRSKSLKEVFES
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: TRPA_STUS1
Sequence: MSRLLTRFDELKQQNRAALVTFITAGDPDYATSLQILKGLPAAGADVIELGMPFTDPMADGPAIQLANIRALAAKQDLAKTLQMVREFRQDDQTTPIVLMGYFNPIHKMGVERFIAEAVEAGVDGLIVVDLPPEHNEDLCDPAQAAGIDFIRLTTPTTDDKRLPVVLNGSSGFVYYVSVAGVTGAGSATLEHVEEAVARLKRHTELPVCVGFGIRTPEQAAAIARLTEGVVVGSALIDQIANAKSNAQAVEGVLELCRQISTGVRSARA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: PCH2_HUMAN
Sequence: MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTEFDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENIIAANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDKQFEERKKLAAYI
What is the function of this protein?
Plays a key role in chromosome recombination and chromosome structure development during meiosis.  Required at early steps in meiotic recombination that leads to non-crossovers pathways.  Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.  Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation.  In males, required for efficient synapsis of the sex chromosomes and for sex body formation.  Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes.  Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity).  Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959).
What are the official names of this protein?
Pachytene checkpoint protein 2 homolog, Human papillomavirus type 16 E1 protein-binding protein, 16E1-BP, HPV16 E1 protein-binding protein, Thyroid hormone receptor interactor 13, Thyroid receptor-interacting protein 13, TR-interacting protein 13, TRIP-13.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. PCH2 subfamily.
Protein: NH127_CAEEL
Sequence: MKITFSPELSIPCEVCKNQSNGYHFEVLSCGACASFFRRSVVSKIKYQCKDGKKRCQIRYLDRHFCRYCRFSKCVKAGMKAEKIQKNRDLDSSPTPTDQNNCIPSDVLHDDGILIKDIRGLFKQFNPHNASEGCSKLEKLTEGLQFIRRNQERECIKIIDEMDSESLKDVQFKVIGSCATWLLFSSFFQKLEENEKVVILERLWHGWTVLEFLSRSLEIFGNKVIDEKIVFISDNTAIRLITAFENSLKTASPKKSESIKKKLELSFSVIFDELALHFINWKPTEIEISYMQWQIVWSVAEQLLSGNSLEKGEHFTEQLSKDLHEYYVRELKLENYAFRIEKMMDIVQIVQNNFY
What is the function of this protein?
Orphan nuclear receptor (Probable).  May play a role in modulation of lifespan and immunity (PubMed:29748542).
What are the official names of this protein?
Nuclear hormone receptor family member nhr-127.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GHRB_KLEP3
Sequence: MKPSVILYKTLPDDLLQRLEEHFSVTQVKNLRPETVSQHAEAFAQAEGLLGSSEKVDAALLEKMPKLRATSTVSVGYDNFDVEALNARRVLLMHTPTVLTETVADTVMALVLSTARRVVEVAERVKAGEWTKSIGPDWFGSDVHHKTLGIVGMGRIGMALAQRAHFGFGMPILYNARRQHPQAEERFNARYCDLDTLLQEADFVCLILPLSEETHHLFGQAQFAKMKSSAIFINAGRGPVVDEQALIAALQAGEIHAAGLDVFEHEPLAKDSPLLTLPNVVALPHIGSATHETRYNMAACAVDNLIDALNGNVEKNCVNPQVK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC3_DESVM
Sequence: MKKMFLTGVLALAVAIAMPALAAAPKAPADGLKMDKTKQPVVFNHSTHKAVKCGDCHHPVNGKEDYQKCATAGCHDNMDKKDKSAKGYYHAMHDKGTKFKSCVGCHLETAGADAAKKKELTGCKGSKCHS
What is the function of this protein?
Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin.
What are the official names of this protein?
Cytochrome c3.
What are the subcellular locations of this protein?
Periplasm.
Protein: RNPH_RHIME
Sequence: MRPSGRKTDQMRKVSFERSFSKHAEGSCLVRFGDTHVLCTASLEEKVPAWLRNGGKGWITAEYGMLPRATGERMRREAATGKQSGRTQEIQRLIGRSLRAVVDLPALGERQISIDCDVIQADGGTRTASITGAWIALHDCLKWMEARNMVKLEKVLKDHVAAISCGIFANQPVIDLDYLEDSAAETDANFVMTGSGGLVEIQGTAEGKPFSEEEFASLMLLAKNGIAELVEMQKQAIAG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: APOC4_ACIJB
Sequence: MLVPGRRPQALPSLCFCILVLACVVACQQEVPAATPSMPPELVDSPWSLMKDKVKTLVTRTREKWQWFWGPEAFQGFVQAYYEDHLKDLRLRTQAWLRSSRDSLLNKAHSLCPQLLCRDGDKN
What is the function of this protein?
May participate in lipoprotein metabolism.
What are the official names of this protein?
Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUCD1_AQUAE
Sequence: MPWAKEGDLQELLKAFPQASVVELQNSTSVIVPKDILIDVLKYLKEKLGYKLFLDHSVVDLKDLLENEKEFNKVVKQNLIAFPEDRESRFQAFYILYNVDERKRVIVKTRTNGKLPTIEKLWFAGKWAERECYDMFGIEYEGHENLVRAFMWDTYPYFPLRKDFPLEGIPEQELPSLNEVVFGDNLEGLMNYDRMHTRVPTLEDLEVTEKKRLKKKAQIVLNWGPLHPGTHGTMWFLFDLEGERIVQTDVILGQLHRGVEKLAEHEMYNQFLVYTDRMDYLSALCSNQAWVVAIERLMGIHDKVPPKAKYIRTMMSELQRINSHLLWLGTYALDLGALTIFLYAFKEREKIMDIIEGITGARLTISYPRIGGVRMDLPEGALEVIKAFIKKFPEELKDWETILTRNRIWLRRNKEVGIISKEDAYFHGVTGPVIRGSGIPYDIRKFEPYDAYDEVEFDIPVGEIGDCYDRYLVRIEEMKQSIRIIEQCVAKLEKMSKNEPFFYEGEGKKLKLSLDGIGVKAPVGEIYSSGENPRGELGFYVVSTGGTSPYRVKIRPPSYYNLCIYPHLMKDRYVADAVTILASIDPVVGETDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D 1, NADH dehydrogenase I subunit C/D 1, NDH-1 subunit C/D 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PAFA_NAKMY
Sequence: MQRRIMGIETEFGITCTFHGQRRLSPDEVARYLFRRVVSWGRSSNVFLRNGSRLYLDVGSHPEYATAECDELPVLIAHDKAGERILQDLVVDAETRLAEEGIGGDIYLFKNNTDSAGNSYGCHENFLIARGGEFAKIADGLIPFLVTRQLIAGAGKVLQSPRGASYCLSQRADHIWEGVSSATTRSRPIINTRDEPHADAERYRRLHVIVGDSNMSETTTLLKVGTAALVLEMIESGVPMRDFTFENPIRAIREISHDTTGRKAVRLAGGGDISALDAQTEYYEKAAAFVANRGTDPVTHQVLDLWRRTLEAVQTQDFTKVDTEIDWIIKKKLIDAYAAKHGLDLTHPRIAQLDLTYHDVRPGRGLHSLLAARGRAARVVTDGQITTAMTVPPQTTRARLRGEFVAAAQDAGRDYTVDWVHLKLNDQAQRTVLLKDPFRSTDDRVTKLIEAM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: HEM3_COREF
Sequence: MTLRIGTRGSKLATTQAGHMRDRLKHFGRDAELTIVTTPGDVNMSPVERIGVGVFTQALRDALVADEIDVAVHSFKDLPTAPDPRFHLVVPTRADARDALIARDGLTLEELPEGAKVGTSAPRRISQLKALRPDLEILPLRGNIDTRMGKVTSGELDAVVLAFAGLSRVGMQDRATQVFDPDMLMPAPAQGALAIECRVEDEDIITGLNMLMHADTYVTAVAERTVLNRLEAGCTAPVAAHATLDGYAGDTMTLTAGVFALDGSEQLVFSAQGAGERPEELAEQVAAQLIEQGAATLLG
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.