PharMolix/UniProtQA huggingface dataset:
Protein: RLMN_ANADF
Sequence: MSAPHDPPRPEPRPDLRSLPLDRLERLVAALGERPFRARQLHRWLQQKGAASLDELTDVPRALRAALAEATTLTTLERATEQRSVDGTIKWTWRTHDGKLVESVYMPEPDRRTLCVSSQVGCAVGCTFCLTGTMGLARNLTPGEIVEQVHRANRRIVELGEGQGPRPLTNLVFMGMGEPLANYRSLKVALDLLLSEDGPNFSHRHVTVSTSGLVPMIRKLGEETPVKLAISLNATTDAQRDALMPINRRYPLAQLLEACRSFPIRNGRRITFEYVLLGGVNDSLEDAVRLARLVRGIPTKVNLIPYNANPGLPYRAPAPERVVEFQETLAARNLTAVVRKNRGGDISAACGQLAAEGGPGDPRRPAPPPLTRLPAAG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STRP1_BOVIN
Sequence: MEPAAGTPGPLIMNNKQPQPPPPPPPATAQPPPGAPRTAGGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRMHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNTFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRAILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ
What is the function of this protein?
Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the cortical actin filament dynamics and cell shape (By similarity).
What are the official names of this protein?
Striatin-interacting protein 1, Protein FAM40A.
What is the protein family that this protein belongs to?
Belongs to the STRIP family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Enriched on the plasma membrane.
Protein: KSR1_HUMAN
Sequence: MDRAALRAAAMGEKKEGGGGGDAAAAEGGAGAAASRALQQCGQLQKLIDISIGSLRGLRTKCAVSNDLTQQEIRTLEAKLVRYICKQRQCKLSVAPGERTPELNSYPRFSDWLYTFNVRPEVVQEIPRDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFNFPAAYFIHHRQQFIFPVPSAGHCWKCLLIAESLKENAFNISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGHFWKSADINSSKVVPRFERFGLGVLESSNPKM
What is the function of this protein?
Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases (By similarity).  Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed:29433126).  Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP (By similarity).  Its kinase activity is unsure (By similarity).  Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown (By similarity).
What are the official names of this protein?
Kinase suppressor of Ras 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Cell projection, ruffle membrane. Endoplasmic reticulum membrane. Note=In unstimulated cells, where the phosphorylated form is bound to a 14-3-3 protein, sequestration in the cytoplasm occurs. Following growth factor treatment, the protein is free for membrane translocation, and it moves from the cytoplasm to the cell periphery.
Protein: PHS_CAUVN
Sequence: MSRPRIGAAAAITQLEGWAIAPNHKDAIVKTFRFDDFNQAFGFMTRVALMADKLDHHPEWFNVYNRVEVLLTTHDADGVTDLDLTLAKFMDSAA
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: I1BW_CONRA
Sequence: GHVPCGKDRRKCGYHADCCNCCLSGICKPSTSWTGCSTSTFLLTR
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels.  Produces general excitatory symptoms (By similarity).
What are the official names of this protein?
Iota-conotoxin-like R11.12.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LSPA_MALP2
Sequence: MIKQFFSNVYEGIKHYSNYLWELSKKQLIKIYLNKKHLIWKISIILICAFIVLLTSFLTRNSILNATQSYWELIPGFLVINITGNTGVSFGTLGDSNPSLVYFVQSIPIVLGFFVLLFSSNYLLDIGVSLVFFGGLSNIIDRSIVDNYKYLSGISTNNAVVDYFQFPFIKNSAIFNFPDTFVIIGMIFVGIQIIISFVKDYKKEKDSEENKKPIKDVVLDEERNKTKKEPIKKPIVIQKS
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y797_LISMF
Sequence: MVWDATNIFLFAANILTVLYILYNDAVIPLWKGKTVLSVKLRSRGRWDGYIFVGIIVLLFVSNTFFREGPFSTSVLLGIMGVLFIYICFFRSSKAVFKESGLFYALLFFPYAKIERMNLSEDGVLVIETNRQRLMLFARSEKDLEKMLAVFTTYS
What are the official names of this protein?
UPF0266 membrane protein LMOf2365_0797.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOLH1_PIG
Sequence: MWNPLHETDSTSVAWRRPRWLCAGALVLAAGLFVLGFLFGWFIKSPNEAANISPQHNVKKAFLDELKAENIKTFLYNFTRIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTRPNYISIIDEDGNEIFNTSLFEPPPPGYENVSDVVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKILIARYGKIFRGNKVKNAQLAGAKGIILYSDPADYFAPGVQSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRLQIAEAVGLPRIPVHPIGYSDAQKLLEKMGGSAPPDDSWKGSLHVPYNVGPGFTGNFSTQKVKMHIHSDNKVKRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGKLKKEGWRPRRTVLFASWDAEEYGLFGSTEWAEENSRILQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELQSPDEGFEGKSLFESWNEKSPSPEFSGLPRISKLGSGNDFEVFFQRLGIASGRARYTKDWVTNKFSSYPLYHSVYETYELVEKFYDPTFKYHLAVAQVRGGIVFELANSVVRPFDCRDYAVVLRNYADKLYNISMNHPQEMKAYSVSFDSLFSAVKNFTEIASNFSERVQDLDKNNPILLRIMNDQLMFLERAFIVPLGLPDRAFYRHVIYAPSSHNKYMGESFPGIYDALFDIENKVDPSKAWGEVKRQISIAAFTVQAAAGTLREVA
What is the function of this protein?
Also exhibits a dipeptidyl-peptidase IV type activity.  In vitro, cleaves Gly-Pro-AMC.
What are the official names of this protein?
Glutamate carboxypeptidase 2, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, FGCP, Glutamate carboxypeptidase II, GCPII, Membrane glutamate carboxypeptidase, mGCP, N-acetylated-alpha-linked acidic dipeptidase I, NAALADase I, Prostate-specific membrane antigen homolog, Pteroylpoly-gamma-glutamate carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28B subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: NTE1_ASPTN
Sequence: MADDGGPFPLSSSLLHASSSTTILESSSSSLLATSSPAIAATFSSFSGRPSSYLPPPPLPPPAPSTMVGWIGWVFSFVFQVIPSILYWAITFCTITLPTWLFTLFSMSLTFTMNFTTLLLIALAIVSTVSWFIRYRFLNMYSRLPPEPQRKEPQLDLFPDVQEGDSKPGLANYLDEFLSAIKVFGYLERPVFHELTRTMQTRKLIAGETLLLEEEKGFCLVVDGLVQIFVKSIRDGKSPADHELNLAGDDSTDEEGQNVDGRQGYQLLTEVKNGASMSSLFSILSLFTEDIQLRTSESLSSSVSSVGPNLARVPDSSPSSPRGLVHSPVPVREPSESGHNLPTNGEFLPTVPPLHLEESRGTPDHDHQPESRTRPGKKRRKSVHPDIVARAMVDTTIAIIPASAFRRLTRVYPRATAHIVQVILTRLQRVTFATAHSYLGLTNEVLGIEKQMTKFTTYDLPNDMRGAALDRLKDKFIKERDRLGHEEVTKGIALHNPSAGRRRRSSSFLRKEAALQARMATTPRRPTATGSQENMSFHDRDAAGVSPGDLLSTIQLSRFGPRYEHLAPKIYSPLAEKEQSPFRPPTMRGPASPFHRKESLDEDALFRESILDCIMKALGLTSSTRDILRKSSHNSGDASPKLLSYDSRRQKAVFSNNAFGFIDPYEGSVDGETESMMSMSVTSAGGTSPIVNLREELRNDIEIVYFPQGSVLVEQGERHPGLYYVIDGFLDVGMPACDKGDDLVGATRPAHGEEAFPTLKRTTTASSRTSSVAPGGSDSKRRRQSRKSLYLIKPGGIQGYVGSVASYRSYTDVLAKTDVYVGFLPRASLERIAERYPIALLTLAKRLTSLLPRLLLHIDFALEWVQVNAGQVIYHQGDESDAIYLVLNGRLRSVLEGTDGKMNVVGEYGQGESVGELEVMTESTRPATLHAIRDTELAKFPRSLFNSLAQEHPGITIQVSKLIAQRMRDLVERPMTEKGAEHGAGSIKTATSTVNLRTVSILPVTAGVPVVEFGHRLLNALHQIGVTNGVTSLNQAAILNHLGRHAFTKMGKLKLSQYLADLEEKYGMVLYIADTNVNSPWTQTCITQADCILLVGLAESTPSIGEYERFLLGMKTTSRKELVLLHADRYCPPGLTRRWLKNRVWINGGHHHIQMGFRLTAEPSHPQTKRFGTVLKERVQVIQAEIQKYTSRRIHQTALYSAQTPFKGDFHRLARRLCGRSVGLVLGGGGARGIAQVGVIKALEEAGIPIDIIGGTSIGAFNGALYARDADVVPMYGRAKKFAGRMGSMWRFALDLTYPTVSYTTGHEFNRGIFKTFGDSQIEDFWLEFYCNTTNISKSRPEYHSSGYVWRYVRASMTLAGLIPPICDEGSMLLDGGYIDNLTVPHMKGLGADVIFAVDVGSIDDNTPQGYGDSLSGFWATINRWNPFSSVPNPPTLSEIQARLAYVSSFENLEQAKTTPGCLYMRPPIDPYGTLDFGKFDEIYQVGYKYGKEYLEKLKNEGTLPLREETEEKKKLQRTLAPRRASI
What is the function of this protein?
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho).  Plays an important role in membrane lipid homeostasis.  Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
What are the official names of this protein?
Lysophospholipase nte1, Intracellular phospholipase B, Neuropathy target esterase homolog.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LMBL1_MOUSE
Sequence: MEGHTDMEILRTVKGSSTGEVNVHLVARDSAGPHPQLPTTAFIIPTNAATLGLPSTALDVPYPREPVHVGALERVAGSEPVTATILPQLSTGTGTNSTVRLLDWTGVSAPLPGSGMRFRINEYAPLNMIGVERPRSPEQRHEGGMARRDAGIQHPDVHQDRQDITSLEPPVDASSCKCQACGPQQSSGLDVGSSGDRCSQPFQKRSVIVENSGCTIASELLKPMKKRKHKEYQSPSEESEPEAVKQGEGKDAEREPTPSTPENEEWSRSQLVSSEKKDGWSWESYLEEQKAVTAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQLPKGYKEEEFSWSQYLRSTKAQAAPKHLFVSQSHSTPPVGFQVGMKLEAVDRMNPSLVCVASVTDVVDSRFLVHFDDWGDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDSFCWEKYLEETGTSAVPNWAFKVRPPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKLHFDGWSHNYDFWIDADHPDIHPAGWCSKTGHPLEPPLRPRESSSVSPGGCPPLSHRSPPHTKTSKYNFHHRKCPTPGCDGSGHVTGKFTAHHCLSGCPLAEKNQSRLKAELSDSETAARKKNPSNLSPRKKPRHQGRIGRPPKYRKIPEEDLQALPPSVVHQSLFMSTLPTHADRPLSVCWEQHCKLLPGVAGISASTVSKWTIEEVFGFVQTLTGSEDQARLFKDEMIDGEAFLLLTQADIVKIMSVKLGPALKIYNAILMFKNTDDAFK
What is the function of this protein?
Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post-translational modifications.  PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/H1-4 at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription.  Recognizes and binds p53/TP53 monomethylated at 'Lys-382', leading to repress p53/TP53-target genes.  Also recognizes and binds RB1/RB monomethylated at 'Lys-860'.  Participates in the ETV6-mediated repression.  Probably plays a role in cell proliferation.  Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis (By similarity).
What are the official names of this protein?
Lethal(3)malignant brain tumor-like protein 1, H-l(3)mbt, H-l(3)mbt protein, L(3)mbt-like, L(3)mbt protein homolog.
What are the subcellular locations of this protein?
Nucleus. Note=Excluded from the nucleolus. Does not colocalizes with the PcG protein BMI1, suggesting that these two proteins do not belong to the same complex (By similarity).
Protein: NOC4L_CHICK
Sequence: MARPALAASLEAVLGDRGNANRVFEILELLAAKEEEDVLCAARTCRRLFAALLRRGELFAGSLPAEEDALRGNYSAEEKYKIWMRHRYNDCVESLSELLGHDSFQVKESSLCTLMKFVELEAECPLVAEQWKGSIAFPRHLLKVVVNGLIPIHEDASLLISRFQEYMEYEDVRYFVMKVVTESIGQVMQKIKERPLPFYQQNVFSLISPINMPNKERDMVKFMMKQDNREEWKVSKLQAHKQAFERMWLTFLKHQLPSGLYKKVLVILHDSILPYMNEPTLMIDFLTVAYGVGGAISLLALNGLFILIHQHNLEYPDFYKKLYSLLDPSIYHVKYRARFFHLADLFLSSSHLPAYLVAAFIKRLSRLALTAPPEALLMVIPFICNLFRRHPACKVLMHRPNGPQDLSEDPYIMEQEEPSESRALESSLWELQSLQNHYHPDVAQAAAILNQSLSEIEDDISGLLELSASELFDKEIKKTSANVPLEFEQVRGLFGKKNDIIAEHFALD
What are the official names of this protein?
Nucleolar complex protein 4 homolog, NOC4 protein homolog, NOC4-like protein, Nucleolar complex-associated protein 4-like protein.
What is the protein family that this protein belongs to?
Belongs to the CBF/MAK21 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Nucleus, nucleolus.
Protein: UREG_RHOPS
Sequence: MSTHHGPLRVGIGGPVGSGKTALMDLLCKSMRERYDIAAITNDIYTKWDAEFLVRSGSLTPDRIAGVETGGCPHTAIREDASMNLAAVAEMRSKFPGLDLVLIESGGDNLAATFSPELADLTIYVIDVSAGDKIPSKGGPGITRSDLLVINKIDLAPYVGASLDKMDADARRMRGERPFVMTNLKTREGLERILSFIETKGGLKPKADTA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IN80B_HUMAN
Sequence: MSKLWRRGSTSGAMEAPEPGEALELSLAGAHGHGVHKKKHKKHKKKHKKKHHQEEDAGPTQPSPAKPQLKLKIKLGGQVLGTKSVPTFTVIPEGPRSPSPLMVVDNEEEPMEGVPLEQYRAWLDEDSNLSPSPLRDLSGGLGGQEEEEEQRWLDALEKGELDDNGDLKKEINERLLTARQRALLQKARSQPSPMLPLPVAEGCPPPALTEEMLLKREERARKRRLQAARRAEEHKNQTIERLTKTAATSGRGGRGGARGERRGGRAAAPAPMVRYCSGAQGSTLSFPPGVPAPTAVSQRPSPSGPPPRCSVPGCPHPRRYACSRTGQALCSLQCYRINLQMRLGGPEGPGSPLLAT
What is the function of this protein?
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
What are the official names of this protein?
INO80 complex subunit B, High mobility group AT-hook 1-like 4, IES2 homolog, hIes2, PAP-1-associated protein 1, PAPA-1, Zinc finger HIT domain-containing protein 4.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: HUTU_STAAR
Sequence: MRKIQAKKGLSIECKGWEQEAVLRMLYNNLDTEVAERPEDLVVYGGIGKAARNWEAFEAIEKTLRELESDETMLVQSGKPVAVFKTHEEAPRVLISNSVLVPEWANWDHFNELDKKGLIMYGQMTAGSWIYIGSQGIVQGTYETFAELGNQHFNGDLAGTVTLTAGLGGMGGAQPLAITMNHGVAICVDVDETRVDKRIATKYCDIKTANLDEALKLAEEAKERGEGLSIGLVGNAVDLHQAILEKGFKIDIITDQTSAHDPLNGYVPQGYSVEEAKVLREKDPKKYVELSQASMAKHVELMLEFHKRGAVAFDYGNNIRQVAFNNGVRNAFDFPGFVPAYIRPLFCEGKGPFRFAALSGDPKDIERADEEMRKLFPENEKLLRWLDLAEEKISYQGLPSRIAWLGYGERAKMGLALNRLVRDGEISAPIVIGRDHLDAGSVASPNRETESMKDGSDAVGDWAVLNALINTAAGGSWISFHHGGGVGMGYSLHAGMVVVADGSERAERRLERVLTTDPGMGVARHVDAGYDIAIQTAKEKGIHIPMIDKAGDK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCRY4_NOTSL
Sequence: CFYEIVDDYLRLFHDKEGRIMYDQMSDMRNRYIDMDGRMTFGTVGGYAVQSRGDGGYYVKSRGDGGYPVQGRGDTGYSSQTRSDDACLGQGRGEVDTGMSYDASTGVCTDINRGDMSSDINSGLYSGGRMDDSCHTSESRRMDDPCGTDESRRLDVPCHSDDHYRSDNPCTDDSCQAEDRRGGHSDSHRIDISSEESASRRSRNHAFAEGRMSEMRLRYMETCRRVLPFMERTLEMQHGGDTFFCGDEMMLCDMMCYCALENPLMENASFFGQYPKLMALRERVASQINISQYIKRRYQSDF
What is the function of this protein?
S-crystallins are structural components of squids and octopi eye lens.
What are the official names of this protein?
S-crystallin SL4.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: MURC_CORJK
Sequence: MSDQLQTTDLSRVHMVGIGGAGMSGIARILLDRGYQVSGSDMKESRSIMALRAAGAQIQVGHAEDNLRLSGEMPTVVVTSFAAIPQDNPELVGAREAGIPVLRRSDILALLLQDRRAFLLAGTHGKTSTTSMAVAALQAAGQDPSFAIGGQLNRAGTNAHNGTGEVFVAEADESDGSFLSYSPEIAVVTNIEPDHLDYFKTESAYREVFEKFAHRIVPGGFLVVCLDDPGSAALAEELIAGAEEGNPLPFTVVGYGTAEGCDAHPSVPPAAIIESTEVTAEGTVSALRLTEEVKKAAEEAAGTYSLRVAIPGIHMVLNAAAAVLGSVLLGADVDKVIAGIGGFDGVRRRFEYHGTRQDVEVYDDYAHHPTEVAAVLAAARQRVEARGGRIVAVFQPHLYSRTMNFADEFAEALSLADQVVLLDIFGAREEPVEGVDSRIIGNKIDASTDWVFEPDFSKVSSVVAGLVQPGDMVLTIGAGTVTMLADEILLELDRGDRG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAAR2_RAT
Sequence: MTSFEAQQETFDCSEYGNGSCPENERSLGVRAAMYSLMAGAIFITIFGNLVMIISISYFKQLHTPTNLLILSMAVTDFLLGFTIMPYSMVRSVENCWYFGLTFCKIHYSFDLMLSITSIFHLCSVAIDRFYAICHPLHYCTKMTIPVVKRLLLVCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFVAGFFTPSSMMVGIYGKIFAVSKKHARVIDNLPENQNNQMRKDKKAAKTLGIVMGVFLLCWFPCFFTILLDPFLNFSTPAILFDALTWFGYFNSTCNPLIYGFFYPWFRRALRYILLGKIFSSHFHNTNLFTQKETE
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Trace amine-associated receptor 2, TaR-2, Trace amine receptor 2, G-protein coupled receptor 58.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZN861_HUMAN
Sequence: MWLSTSPYRKGSQCGEAFSQIPGHNLNKKTPPGVKPPESHVCGEVGVGYPSTERHIRDRLGRKPCEYQECRQKAYTCKPCGNAFRFHHSFHIHERPHSGENLYEC
What are the official names of this protein?
Putative zinc finger protein 861.
Protein: UPP_VIBCH
Sequence: MKIVEVKHPLVKHKLGLMREGDISTKRFRELATEVASLLTYEATSDFETEKVTIEGWNGPVQVDQIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFNKLATNIEERIAMVVDPMLAIGGSMIATIDLLKEKGCNQIKVLVLVAAPEGIAALEKAHPDVELYTAAIDEKLNDKGYIVPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NUSB_SHIBS
Sequence: MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDVLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKVAINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RBFA_BURPS
Sequence: MSKKRSSPNRNVQIADQIQRDLSELIMREVKDPRIGIVTIQSVELTPDYAHAKVYFTALTGTPADTQEALNHAAGHLHNLLFKRLHIHTVPTLHFHYDQTIEKAVAMSRLIDEANATRAKDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_RALPJ
Sequence: MNIHEYQGKEILRKYNVPVPRGIPAFSVDEAIKAAETLGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVKEYASSILGMTLVTHQTGPEGKLVKRLLIEEGADIKKELYVSLVVDRVSQQVALMASSEGGMDIEEVAESHPEKIHTLLIDPQAGLQDAQADDIARKIGVPDASVPQARQALQGLYKAFWETDASQAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDVKAILVNIFGGIMRCDVIAEGVIAAAKAVSLSVPLVVRMKGTNEDLGKKMLADSGLPIIAADTMAEAAEKVVAAAAGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: COQ4_RAT
Sequence: MATLLLRSQRLHRSLRHRTRPTVDVLLRAASHGARLLYPDHIPTTPLQKMLLAAGAAGMALYNPYRHDMVAVLGETTGCHTLKFLRDQMKKDPEGAQILQERPRISLSTLDLSKLQSLPEGSLGREYLRFLNANKVSPDTRAPTRFVDDEELAYVIQRYREVHDMLHTLLGMPTNMLGEVVVKWFEAVQTGLPMCILGALFGPVRLRAQSLQVLFSELIPWAIQNGRRAPCVLNIYYEQRWEQPLTALREELGISPPPKHIQGLA
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ELFD_ECO57
Sequence: MKTCITKGIVTVSLTAILLSCSSTWAAGKGGVGLAATRLVYSEGEEQISLGVRNTSPDVPYLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGAPLAKDRETLFFTSVRAVPSTTKREEGNTLKIATQSVIKLFWRPKGLAYPLGEAPAKLRCTSSADMVTVSNPTPYFITLTDLKIGGKLVKNQMISPFDKYQFSLPKGAKNSSVTYRTINDYGAETPQLNCKS
What is the function of this protein?
Part of the elfADCG fimbrial operon, which could be required for adherence to host epithelial cells.  Could be required for the biogenesis of the ElfA fimbriae.
What are the official names of this protein?
Probable fimbrial chaperone protein ElfD.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.