PharMolix/UniProtQA huggingface dataset:
Protein: SEH1_MOUSE
Sequence: MFVARSIAADHKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSESGDWHCTASWKTHSGSVWRVTWAHPEFGQVLASCSFDRTAAVWEEIVGESNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHMGLMLATCSADGIVRVYEAPDVMNLSQWSLQHEVSCKLCCSCISWNPSSSRAHPPMIAVGSDDSSPNSMAKVQIFEYNENTRKYAKAETLMTVTDPVHDIAFAPNLGRSFHILAVATKDVRIFTLKPLRKELTSSGGPTKFEIHIVAQFDNHNSQVWRVSWNITGTVLASSGDDGCVRLWKANYMDNWKCTGILKGNGSPVNGSSQLGNSNPSLSSNIPNLQNSLNGTSASRKHS
What is the function of this protein?
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway.  Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex.  It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
What are the official names of this protein?
Nucleoporin SEH1, GATOR complex protein SEH1, Nup107-160 subcomplex subunit SEH1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex. Lysosome membrane.
Protein: AGRIN_HUMAN
Sequence: MAGRSHPGPLRPLLPLLVVAACVLPGAGGTCPERALERREEEANVVLTGTVEEILNVDPVQHTYSCKVRVWRYLKGKDLVARESLLDGGNKVVISGFGDPLICDNQVSTGDTRIFFVNPAPPYLWPAHKNELMLNSSLMRITLRNLEEVEFCVEDKPGTHFTPVPPTPPDACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEAVAPSTHPTSASVTVTTPGLLLSQALPAPPGALPLAPSSTAHSQTTPPPSSRPRTTASVPRTTVWPVLTVPPTAPSPAPSLVASAFGESGSTDGSSDEELSGDQEASGGGSGGLEPLEGSSVATPGPPVERASCYNSALGCCSDGKTPSLDAEGSNCPATKVFQGVLELEGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFRSVRLRDLGPGKSVRAIVDVHFDPTTAFRAPDVARALLRQIQVSRRRSLGVRRPLQEHVRFMDFDWFPAFITGATSGAIAAGATARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPKSRKVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESELANEIPVPETLDSGALHSEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELRPCPTP
What is the function of this protein?
This released fragment is important for agrin signaling and to exert a maximal dendritic filopodia-inducing effect.  All 'z' splice variants (z+) of this fragment also show an increase in the number of filopodia.
What are the official names of this protein?
Agrin.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted, extracellular space, extracellular matrix. Note=Synaptic basal lamina at the neuromuscular junction. SUBCELLULAR LOCATION: [Isoform 2]: Synapse. Cell membrane; Single-pass type II membrane protein.
Protein: RS8_ANAMM
Sequence: MSLSDPIADFLTRLRNGQAGMNKVVFVPHSKVVRSILDILLAEGYIEGFTEESKSSGIKYLKVCLKYYNCAPVIKKIVRVSRPGKRVYSSADRLPKFYNGLGVYIVSTSQGVMLDYRARKLGIGGEILCGVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: K0930_XENLA
Sequence: MISAIVDERNRMNIRQEISGLGCFKDDRIVFWTWMYSTYFMEKWAPRQDDMLFYVRRKPAYMGPDGNEGRKQVEVEVYRKDSKKLPGLGDPDIDWEESVYLNLILQKLDYMVTCAVCTRSDAGDIHIHKKKSQQVFASPSKHPMDSKGEESKISYPNIFFMIDNFEEVFSDMTVGEGEMVCVELVARDKTNTFQGVIFQGSIRYEALKKVYDNRVSVAAKMAQKMSFGFYKYNNMEFVRMKGPQGKGHAEMAVSRVSTGDTSPYGTEEDSNPGSPMHERVTSFSTPPTPERNNRPSFFSPSLKRKVPRNRNAEMKKSHSANDSEEFFRDSDDDGDLHNVTNLRSRSLSGTGRSLVGSWLKLNRTEENALLYAHLTYVTLPLLRILSDILDVRQKPILMS
What are the official names of this protein?
Uncharacterized protein KIAA0930 homolog.
Protein: RL7_BARHE
Sequence: MADLAKIVEDLSNLTVLEAAELSKLLEEKWGVSAAAPVAVAAVAGAAAPVAEEKTEFDVILVEGGAQKINVIKEVRALTGLGLKEAKDLVEGAPKPIKEGASKDEAEKIKSQLEAAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: DAPF_PSESM
Sequence: MLLRFTKMHGLGNDFMVLDLVSQHAHILPKHAKQWGDRHTGIGFDQLLLVEAPNNPDVDFRYRIFNSDGSEVEQCGNGARCFARFVLDKRLTAKKQIRVETKGGIIELEIRSDGQISVDMGPPRLVPEEIPFQAAEQAKSYSLDVDGQTVELAAVSMGNPHAVLRVDDINNAPVHTLGPKIEHHPRFPARVNVGFLHVVDRQRAQLRVWERGAGETQACGTGACAAAVAAISQGWMDSPLLIDLPGGRLSIEWAGPGHPVMMTGPATRVYEGQVRL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_STAAC
Sequence: MKTGRIVKSISGVYQVDVNGERFNTKPRGLFRKKKFSPVVGDIVEFEVQNINEGYIHQVFERENELKRPPVSNIDTLVIVMSAVEPNFSTQLLDRFLVIAHSYQLNARILVTKKDKTPIEKQFEINELLKIYENIGYETEFIGNDDDRKKIVEAWPAGLIVLSGQSGVGKSTFLNHYRPELNLETNDISKSLNRGKHTTRHVELFERQNGYIADTPGFSALDFDHIDKDEIKDYFLELNRYGETCKFRNCNHIKEPNCNVKHQLEIGNIAQFRYDHYLQLFNEISNRKVRY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_CAMFF
Sequence: MNKSCIYPGTFDPITNGHMDVIKRACRVFDNVIVAVALNESKTPYFCYEERISLAKTATKDIPKVSVIGFDNLLVDLAKSKGINTVVRGLRAVSDFEYELQIGYANASLWSEFETVYFMPSLKNAFISSSIVRSVLKHGGDIGSLVPTNVLEEIKGKLC
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_HAEIN
Sequence: MSDTLLNPYFGEFGGMYVPEILVPVLKQLEQAFVEAQNDPTFQAEFADLLKNYAGRPTALTLCRNLTKGTKTKLYLKREDLLHGGAHKTNQVLGQILLAKRMGKTRIIAETGAGQHGVATALACAMLDMPCRVYMGAKDVERQSPNVFRMRLMGAEVIPVQKGSCSLKDACCEAMRDWSANYETTHYLLGTAAGPHPFPTIVREFQKMIGEETKRQILEREGRLPDTVIAAVGGGSNAIGMFADFIDESNVRLIGVEPAGKGIETGEHGAPLKHGTTGIYFGMKSPIMQDKDGQIEESYSISAGLDFPSVGPQHAYLNEIGRADYVSITDEEALNAFQELAKHEGIIPALESSHALAYALKLIKQNPEKEQLLVVNLSGRGDKDIFTVDKILNGGAN
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ALBE_BACSU
Sequence: MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLKEQIIDAFGYAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKTFADLSFPSSLSFEAFEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRRDRIKAIHPKRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRHVFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYDVMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGLLAYMGVLRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG
What is the function of this protein?
Involved in the production of the bacteriocin subtilosin.
What are the official names of this protein?
Antilisterial bacteriocin subtilosin biosynthesis protein AlbE.
Protein: RECF_DESHD
Sequence: MEIKWLHLKSFRNYQDQEVDFRPGLTILQGENGQGKTNILEGIYYLLTGKSYRVHREQELARWGENEFHLYGDFIVQRRKLRLESHYQDKRKIIKINQIPCRKLSEYVGTINVVFFSPDDLVMVKGGPAERRRFLDLHIAQHHSKHIQLLNAYNKVLQQKNALLKQGQGGSKSQIAQIELWNEQILRIGSEIIRNRWEFTGLLSRKGQEIYGQISSGKEELTMDYHALGKNNLEEALAAFPKLLAEKMSLEMERKMVLIGPHRDDILFKLNERSARLYGSQGQQRSIVLSTKLAELEVIRQEKGDYPLLLLDDVLSELDRFRRDYLLDYTKSLQQTIMTMTSAETLTQRASLLLKVEKGQIGRIE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_MESH7
Sequence: MGKYNRILALDLGIKTCGFAISDQNWKISYPLEQFNFNRYDFASVISRIAFWMKEYPISILVLGYPLTLAGKISPRTKMVEYFADLVKKNYEIKVVFQDERLTTKQAQTFLLDLGISFKKRQKVIDKLAAQIILERFLNTKKG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITD1_SALTI
Sequence: MKINQLAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGEAIRATILEVLSRYDVRGVQLNVDDKGALDCILRARLETLLARASGIAALPWEDRQ
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein 1, Citrate lyase gamma chain 1.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMT2_SCHPO
Sequence: MFAQALHWLTTSKLRYALALPFLFFILYTKTKKSKEQELENYIFSLPREKLDQIRGKPDEVINVIDEYVEQGHFLMNIGKLKGKIISEKIQQVKPKVMIELGGYVGYSAILFGKQLTDPSAHYYSLEVNPKFAKIASKIIDLAGLSNKVTIIVGKATDSLVELRRSLPNVIPSFEYLDFVFIDHWKDLYVPDLRVMETLDLIGQGSIIAADNILRPGVPEYVKYVQGSLDYRKEYDSTVSNVNGPQFIGKWNIIYKSKTIKVDDGKREKDAVEITEYIEAK
What are the official names of this protein?
Probable catechol O-methyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: DOCK2_MOUSE
Sequence: MAPWRKTDKERHGVAIYNFQGSEAQHLTLQIGDVVRIQETCGDWYRGYLIKHKLSQGIFPTSFIHLKEVTVEKRRNIENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSMMYDLMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDKTSVISLFHAHEEATYKITERIKEEMSKDQPDYGVYSRISSSPTHSLYVFVRNFVCRIGEDAELFMSLYDPHKQTVISENYLVRWGSKGFPKEIEMLNNLKVVFTDLGNKDLNRDKIFLICQIVRIGKMDLKDINAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVSAENDFLHSLLGKVIASKGDSGGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPGDVRNDIYITLLQGDFDKYTKTTQRNVEVIMCVCTEDGKVLPNAICVGAGDKAMNEYHSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGTTLHDGYHELVVLKGDSKKMEDASAYLTLPSYRHPVENKGATLSRSSSSVGGLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIMMEHSQSNEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNLMKSQYKTTILLQVAALKYIPSVLHDVETVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQRDDGQHQAEKKHCVELLNSILEVLSCQDAAFTYDHIQEIMVQLLRTVNRTVITMGRDHALISHFVACMTAILDQMGDQHYSFYIETFQTSSDLVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFLEHTSFEFQLWNNYFHLAVAFITQDSLQLEQFTHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEMTLIPEAELRKATIPIFFDMMLCEYQRTGAFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECTAEHPTIAKSVENFVSLVKGLLEKLLDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCENYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLTQQAKFYENIMKILRTKPDYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLLSQFPNAEKMNTTSAPGDDVRNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQKFHYSRPVRRGKVDPENEFASMWIERTSFLTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTVNEKILMMINQYQSDESLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYSREHPEDQDKLSHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFEDRRVGRPRSMLRSYRQMSVISLASMHSDCSTPSKVPAESFDLESAPPKTPKVEEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAATESDLKRLSRKQEFMSDTNLSEHAAIPARVSILSQMSFASQSMPTIPALTLSVAGVPGLDEANTSPRLSQTFFQVSDGDKKTLKKKKVNQFFKTMLASKSSEESKQIPDFLSTNM
What is the function of this protein?
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines.  Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP.  May also participate in IL2 transcriptional activation via the activation of RAC2.
What are the official names of this protein?
Dedicator of cytokinesis protein 2, Protein Hch.
What is the protein family that this protein belongs to?
Belongs to the DOCK family.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Colocalizes with F-actin.
Protein: ALAE_SODGM
Sequence: MRWSCHPMSSVTSRLRSATADTFALVVYCFFTGMAIEILLSGMSLQQSLSSRVLAIPVNVIIAWPFGQYRDAVVSLASRHGPKQFWTRNLADLLAMSVFNHRSMRRFFLRWGWSGGSCSRRWSAMR
What is the function of this protein?
Exports L-alanine.
What are the official names of this protein?
L-alanine exporter AlaE.
What is the protein family that this protein belongs to?
Belongs to the AlaE exporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DAPA_HELMI
Sequence: MEFGRLITAMVTPFNDRLEVDYVRAAELANHLVNTGSDGIVVAGTTGESPTLTKDEKIRLFSTVVDAVGDRASVIAGTGSYDTEATIELSRKAKEAGVDGLLLVGPYYNKPPQEGYYQHFAAVAKAVPLPIMLYNIPGRTGSNIIPATVARLMAFDNIVAIKEAAGSMDQVSEVVRLARPDFKVYSGDDSLTLPILSVGGHGIVSVASHLVGKEIQKMIAACINGNISEAARIHRELYPLFKGLFITSNPICVKAALNLLGRPVGGVRLPLVEANDQEVAAMRQLIESYGLDASCQETVA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRI1_YEAST
Sequence: MTNSVKTNGPSSSDMEYYYKSLYPFKHIFNWLNHSPKPSRDMINREFAMAFRSGAYKRYNSFNSVQDFKAQIEKANPDRFEIGAIYNKPPRERDTLLKSELKALEKELVFDIDMDDYDAFRTCCSGAQVCSKCWKFISLAMKITNTALREDFGYKDFIWVFSGRRGAHCWVSDKRARALTDVQRRNVLDYVNVIRDRNTDKRLALKRPYHPHLARSLEQLKPFFVSIMLEEQNPWEDDQHAIQTLLPALYDKQLIDSLKKYWLDNPRRSSKEKWNDIDQIATSLFKGPKQDSHIIKLRECKEDLVLMTLYPKLDVEVTKQTIHLLKAPFCIHPATGNVCVPIDESFAPEKAPKLIDLQTEMEKNNDVSLTALQPFINQFQAYVSSLLKNELGSVKREREDDDEPASLDF
What is the function of this protein?
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.  In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase.  Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48.
What are the official names of this protein?
DNA primase small subunit, DNA polymerase alpha:primase complex p48 subunit, DNA polymerase-primase complex p48 subunit, Pol alpha-primase complex p48 subunit, DNA primase 48 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: ANDR_PANTR
Sequence: MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSAPECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDSAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQEGDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
What is the function of this protein?
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation.  Transcription activation is also down-regulated by NR0B2.  Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
What are the official names of this protein?
Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Detected at the promoter of target genes. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
Protein: STS2_STEHR
Sequence: MVRSPVSDKFCIPDTLASWPYPRILNPHYAEEKAASAAWTKGFGAFGPKAQDAFDRCDFNLLACLAYPIATPERCRSGCDLMNLFFVIDEHSDTHGEETVRKMKDVVMDAIRNPHKPRPNDEWIGGEIARQFWERAMCYASEISQRRFIDTFDEYLESVVDQAADRDSARIRDIESYINIRRNTIGAKPSFVIMEQGMDIPDNVFENEVFQRLRMATIDMLCLGNDIVSYNIEQARGDDSHNIVRIVMNELDTDVPRAMDWVAQRHTQLEREFFTALSELPTWGEPIDGWVKEYVYGLGNWVRANDQWSFESQRYFGTKGMEIMKSRWLSVLPKVRPAEVGPQLVDQSLL
What is the function of this protein?
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to delta(6)-protoilludene (PubMed:24166732, PubMed:26239156).  In presence of Ca(2+), a significant switch from 1,11 to a dual 1,11/1,10 cyclization occurs, producing beta-elemene as the major product, with lower levels of delta(6)-protoilludene and (E)-beta-caryophyllene, and traces of beta-selinene and alpha-selinene (PubMed:26239156).
What are the official names of this protein?
Delta(6)-protoilludene synthase STEHIDRAFT_64702, Terpene cyclase STEHIDRAFT_64702.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: NRDR_GEOKA
Sequence: MRCPSCHHSGTRVLESRPVEEGRSIRRRRECEQCHYRFTTFERIEEPPLIVVKKEGTREEFSREKILRGLIKACEKRPVALEELEKVTQEIERELRNQGVSEVKSETIGEMVMERLSHIDEVAYVRFASVYRQFKDINVFIEELKELIKKGQR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: K1522_MOUSE
Sequence: MVVFLGRHLPALLEVFKKGSAKAESDNRQGAGPSQGPGSVGDELQDNVFFPSGRPPHLEELHTQAQEGLRSLQHQERQKLSKGGWDHGDTQSIQSSQTGPDEDTISIYSQKSYMTESSTAEDALSVRSEMIQRRGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQHVQKELGLRNNREAPGTPQPPGSRDAVRIPTVDGRPGLALGTGVRVSLQALEAETEAGTDAEAVIQRHIDRVYHDDTLVGRSTGARPPPLTRPMSLAVPGLTGGAGSPEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRSSLRTLSRCSLLSASPASVRSLGRFSSASSPRPRSRNASSSSDNWSHSQSSETIVSDGSTLSSKGGSEGQPEGSVASNNVAPPPPGGSGRGSPSGGSTAETSDTASIRSSGQLSGRSVSLRKMKRPPPPPRRTYSLHQRGSAVPDGPLGLPPKPERKQQPQLPRPPTAGGSSGVGAVSCPPSSAGTWGSGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAVAPASPGKAQPPKPDRVTSLRSPGASVSSSLTSLCSSSSDPTPLDRSGPQMSTPLSDRFVIPPHPKVPAPFSPPPSKSKSSNQAAPVLAAPAVAPGQVSTIDTSPASPSMPQTTLTPAQESPVASKDESPPPSPPPSYHPPPPPTKKPEVLEEAPPPPEAAVEILPDPSWPPPPPPAPEEQDLSMADFPPPEEVFFNAGPELGPLESCSSEAAVPPAASLSQTPPPAPPPSSGSEPLARLPQKDSVGKHSGAPREDSGTPLVTPSLLQMVRLRSVGASTGIPNPSPGSSAPQKPLRRALSGRASPVTAPSSGLHAAVRLKASSLAASESPASALPTGIPEAEPRSPQSPASKASFIFSKGTKKLQLERPVSPEAQADLQRNLVAELRSISEHRPPPQAQKKPSKAPPPVARKPSVGVPPPSPSLPRTESLTAPSTNGLPHAEDRTNGELAENGGVQLAATEKMGSPGSDPQKKLV
What are the official names of this protein?
Uncharacterized protein KIAA1522.
Protein: MSBA_WIGBR
Sequence: MLKKNFSTWRIFCRLWPIISPFKSGLIISIVALIINATSDTLMLSLLKPLLDNGFKSSENKISIWMPLAIVALMLSRGSSGFISSYFISWVSGKVVMNIRRNLFRHMMNMPVSFFDKRSTGALLSRITYDTEQVASSSSSVLITIVREGSLIIGLFFMMFFHSWKLSSVLIIITPIVFFSINQVSKRFRKINKKIQNNMGQVNFIVEQMLKGHKEIRIFGGQKEEIDRFNYVSNFIRQQSMKIVISSSTLDIIIQFISSITLAVILYISSLPKIIDELTAGTITVIFTSMIALMRPLKSLTNVNANFQKGMVACKTLFSIFDIKQEQDIGKCYINRARGEIKFKNITFTYPGKENPSLKDINIKISAGCTVALIGSSGAGKSTIVNLLTRFYEADKGSIFLDNINLKKYKLSNLRNQIALVSQNIYLFNDTIANNIAYAKKKIYSKYQIEKAAYMAYAMDFIIKMKHGLNTIIGENGTLLSGGQRQRIAIARALLRDCPILILDEATSALDIESEIKVQKAIDKIRKNRTSLVIAHRISTIKKSDMILLVEKGKIIEYGNHNELIEKKGVYAQIYRLQLDQ
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y078_METJA
Sequence: MNCEEYRKKLKLNYGNREKLKVLKELYQMEVDEITKLNILDDVFELLTSTKERGFEDIISTHYTSDSKNKAIIYYCIKIIEKVGIKYPNLVYIYIPYLIKLLDSEFECIRFASAEALANIPSKLTIYAYPKLIKKLDNEVYAKVLVKLIMKSDNKEAILLKLFENFNEYSLYVIKELYKYDKELVYEFIPLILKEFGNNGLYSFLQK
What are the official names of this protein?
Uncharacterized protein MJ0078.
Protein: RL35_LEPCP
Sequence: MPKMKTKSSAKKRFRVRPGGTVKRGQAFKRHILTKKTTKNKRHLRGTVAVHETNMGHIAQMLPFAGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ARGC_CALBD
Sequence: MIKASIIGASGYVGVELIRLLLRHPEVEIVSIISSSSNQLSIDKTNPQFKKVSNLVFEEFKIEAIQEADVVFCALPHGISQEYVKIGYDIGKVVIDLSADFRYKDLQRYAKDYSQHKYPELLSKSAYGLCEINREEIKNAQIIGNPGCYPTSAILGLAPLLKNKLVDKNSIIIDSKSGVSGAGKKFDFAYSFCELDENFKAYSVTKHRHTSEIEEKCSFLFGEDLNLSFTPHLLPVKRGILSTIYANLIKKIDKNDLVEIYNEFYKDEYFIRIFEDELPELKYVRGTNFVDIGFEVDKKTNRVIIISCIDNLIKGAAGQAIQNMNIKFSLDEKMGLIMVGEYF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.