PharMolix/UniProtQA huggingface dataset:
Protein: ZFY1_XENLA
Sequence: MEDVAELELQTTEPHAFFHASGVGERHLNGNEIIVEIQETVFVADGDGNMAVQGFGPDEGDSVVIQDVIEDVVIEDVQCSDILDGGRVSEAVIIPEQVLEDEVGTGEEEQVLEEDSLTSCDVPDNVLDPELVDGELTIPDPETGMHSVSGHVVIGEEITDDALEEDMISEEVLVADCVSEAVIDANGIPVHENDSEEVNCDDYLMISLDDAEKIDEDGAEEITMGSVVEGDSSKLDGSCPEVIKVYIFKADPGEEDLGGTVDIVESESENDHGDGFLDSHNGGRLPREKMVYMTVNDSQNDDDLDVAEIADEVYMEVIVGEEDAAVAHEHQLEDAELSKTFMPVAWAAAYGNNTDGIEHRNGTASALLHIDESDGLDRLTKQKLKKKRRGENRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLVRKKYRCTDCDYTTNKKVSLHNHLESHKLTATVIKTEKDLECEECGKIFLHANALFAHKLTHNEKAGNKMHICKFCDYETAEQGLLNRHLLAVHSKSFPHICVECGKGFRHPSELKKHMRTHTGEKPYLCQYCDYRSADSSNLKTHVKTKHSKEMPFKCDICLQTFTDSKDLQEHAILHQESKNHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCEVCEKGFHRPSELKKHEAAHKGKKMHQCRHCEFHIADPFVLSRHILSVHTKELPYRCKRCKKGFRQQIELKKHMKTHSGKKVYQCEYCEYNTTDASGFKRHVISIHTKDYPHRCDYCKKGFRRPSEKNQHTLKHHKEASLM
What is the function of this protein?
Probable transcriptional activator.
What are the official names of this protein?
Zinc finger Y-chromosomal protein 1, ZFY-1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRAP_STAAM
Sequence: MSKRQKAFHDSLANEKTRVRLYKSGKNWVKSGIKEIEMFKIMGLPFISHSLVSQDNQSISKKMTGYGLKTTAVIGGAFTVNMLHDQQAFAASDAPLTSELNTQSETVGNQNSTTIEASTSTADSTSVTKNSSSVQTSNSDTVSSEKSEKVTSTTNSTSNQQEKLTSTSESTSSKNTTSSSDTKSVASTSSTEQPINTSTNQSTASNNTSQSTTPSSVNLNKTSTTSTSTAPVKLRTFSRLAMSTFASAATTTAVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDVKAPTVTVGNQTIEVGKTMNPVVLTTTDNGTGTVTNTVTGLPSGLSYDSATNSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDQSSEVYSPISPIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTISIVSTDASGNKTTTTFKYEVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTSASTSKSTSVSLSDSVSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSGSVSKSTSLSDSISNSNSTEKSESLSTSTSDSLRTSTSLSDSLSMSTSGSLSKSQSLSTSISGSSSTSASLSDSTSNAISTSTSLSESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDSKSMSTSESLSDSTSTSGSVSGSLSIAASQSVSTSTSDSMSTSEIVSDSISTSGSLSASDSKSMSVSSSMSTSQSGSTSESLSDSQSTSDSDSKSLSLSTSQSGSTSTSTSTSASVRTSESQSTSGSMSASQSDSMSISTSFSDSTSDSKSASTASSESISQSASTSTSGSVSTSTSLSTSNSERTSTSVSDSTSLSTSESDSISESTSTSDSISEAISASESTSISLSESNSTSDSESQSASAFLSESLSESTSESTSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSASISTSTSISESTSTFKSESVSTSLSMSTSTSLSNSTSLSTSLSDSTSDSKSDSLSTSMSTSDSISTSKSDSISTSTSLSGSTSESESDSTSSSESKSDSTSMSISMSQSTSGSTSTSTSTSLSDSTSTSLSLSASMNQSGVDSNSASQSASNSTSTSTSESDSQSTSTYTSQSTSQSESTSTSTSLSDSTSISKSTSQSGSTSTSASLSGSESESDSQSISTSASESTSESASTSLSDSTSTSNSGSASTSTSLSNSASASESDSSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTIASLSTSVSTSESGSTSESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTSDSRSTSASTSTSMRTSTSDSQSMSLSTSTSTSMSDSTSLSDSVSDSTSDSTSASTSGSMSVSISLSDSTSTSTSASEVMSASISDSQSMSESVNDSESVSESNSESDSKSMSGSTSVSDSGSLSVSTSLRKSESVSESSSLSGSQSMSDSVSTSDSSSLSVSTSLRSSESVSESDSLSDSKSTSGSTSTSTSGSLSTSTSLSGSESVSESTSLSDSISMSDSTSTSDSDSLSGSISLSGSTSLSTSDSLSDSKSLSSSQSMSGSESTSTSVSDSQSSSTSNSQFDSMSISASESDSMSTSDSSNISGSNSTSTSLSTSDSMSGSVSVSTSTSLSDSISGSTSVSDSSSTSTSTSLSDSMSQSQSTSTSASGSLSTSISTSMSMSASTSSSQSTSVSTSLSTSDSISDSTSISISGSQSTVESESTSDSTSISDSESLSTSDSDSTSTSTSDSTSGSTSTSISESLSTSGSGSTSVSDSTSMSESDSTSVSMSQDKSDSTSISDSESVSTSTSTSLSTSDSTSTSESLSTSMSGSQSISDSTSTSMSGSTSTSESNSMHPSDSMSMHHTHSTSTSRLSSEATTSTSESQSTLSATSEVTKHNGTPAQSEKRLPDTGDSIKQNGLLGGVMTLLVGLGLMKRKKKKDENDQDDSQA
What is the function of this protein?
Mediates binding to human platelets, possibly through a receptor-ligand interaction.  Probably associated with virulence in endovascular infection (By similarity).
What are the official names of this protein?
Serine-rich adhesin for platelets, Adhesin SraP, Staphylococcus aureus surface protein A.
What is the protein family that this protein belongs to?
Belongs to the serine-rich repeat protein (SRRP) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Exported by the accessory SecA2/SecY2 system. Anchored to the cell wall by sortase A (By similarity).
Protein: UCRI_PANPA
Sequence: MLSVAARSGPFAPVLSATSRGVAGALRPLVQATVPATPEQPVLDLKRPFLSRESLSGQAVRRPLVASVGLNVPASVCYSHTDVKVPDFSEYRRLEVLDSTKSSRESSEARKGFSYLVTGVTTVGVAYAAKNAVTQFVSSMSASADVLALAKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTQKEIEQEAAVELSQLRDPQHDLDRVKKPEWVILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRLGPAPLNLEVPTYEFTSDDMVIVG
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).  UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer.  One of the fragments, called subunit 9, corresponds to its mitochondrial targeting sequence (MTS) (By similarity).  The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function (By similarity).
What are the official names of this protein?
Cytochrome b-c1 complex subunit Rieske, mitochondrial, Complex III subunit 5, Cytochrome b-c1 complex subunit 5, Rieske iron-sulfur protein, RISP, Rieske protein UQCRFS1, Ubiquinol-cytochrome c reductase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: YVBG_BACSU
Sequence: MMFSFIVHVFISLFAVSNPIGNVPIFLTLTEGYTAAERKAIARKAAILSFFILAAFLVFGHLIFKLFDINIHALRVAGGIFIFGIAYNLLNAKESHVQSLHHDEHKESKEKADISVTPLSIPIIAGPGTIATVMSLSAGHSGIGHYAAVMIGIAAVIALTFLFFHYSAFISSKLGKTEMNVITRLMGLILAVVAVGMIGAGLKGMFPVLTS
What are the official names of this protein?
UPF0056 membrane protein YvbG.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPA_PROMT
Sequence: MNKSALLSPAPFGRLLTAMVTPFDDEGKVDYGLAADLANYLVDQGSDGIVVCGTTGESPTLSWQEQQKLLETVRNSLGSRAKVLAGTGSNSTSEAIEATKEAANSGADGALVVVPYYNKPPQEGLEVHFRAIANAAPKLPLMLYNIPGRTGCSISPSIVSKLMDCSNVVSFKAASGTTEEVTQLRNYCGSDLAIYSGDDALVLPMLSVGAVGVVSVASHLVAPNLKKLIESFLEGKYSEALYLHETLQPLFKSLFATTNPIPVKAALQLIGWSVGPPRSPLVSLNSEMKEELVKILSSLRLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPHB_META3
Sequence: MIILAGLGLYDEKDTTLKTVEFAKKADKIYAEFYTAILTGTTIEKIEETLGKEITILDREKVELETEKLINESKDKDIMFLTAGDPMVATTHIDIAIEAKKKGIEVIILNAPSIYSAIGITGLQLYKFGKTTSIVFPEPNYFPETPYDVIKENSKMGYHTLCLLDIQAHNTRFMTANEGLEVLLKIEEKRNENILNKDTKVVVVARAGSLKPKMVYGKIGDLLEYDFGAPLHCIIFTGNLHFMEEDALKYLCENISE
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: PAFP_PHYAM
Sequence: MAKVSSAYLKFALVMILLLSVISAVMSAGCIKNGGRCNASAGPPYCCSSYCFQIAGQSYGVCKNR
What is the function of this protein?
Possesses antifungal activity.
What are the official names of this protein?
Antimicrobial peptide 1, AFPS-1, Anti-fungal protein 1, PAFP-S, Pa-AMP-1, AMP1.
What is the protein family that this protein belongs to?
Belongs to the AMP family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF3_ECO8A
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVQASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVSRLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LNF_RHOPR
Sequence: VAAGRPRF
What is the function of this protein?
Neuropeptide.
What are the official names of this protein?
Long neuropeptide F, Rhopr-LNF.
What are the subcellular locations of this protein?
Secreted.
Protein: RL9_ACICJ
Sequence: MAQVELILLQRVEHLGQMGEVVKVKPGYARNFLLPQAKAVRATKQNRERFERERAHLEAQNLKRREEAERVAERVAGLTVTLIRQASDAGSLYGSVTSRDIADACGEASLGITRSQVLLVHPIKTLGLATVRVALHPEVLIDVVVNVARSPEEAEKQARGEAIMREESEYELETGEEVAEGPEQTA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: FRZG_MYXXA
Sequence: MAFRVLMVGKGLRALAARGLFDGESLVPVGPAEVDFAGALVAVQRHFPDVVLVDLSALDALPAIEHVMVERPVPVLALHPGVLSGQEAFQAMVAGALDVLERPANPGPEFWTHVSRKLVLLAQVKAVRQVQTRPPPQAAREAKPPPPYPLVAIAASLGGPKAVAQVLRMIPRAFPAPIAYCQHISDGFTEGLAHWLSNETALRVLEAEHDVLMAPGTVYIAPSGSHLLVRPEGRLELDAGPALRGFRPSCDMLLTSAGESFGPRCIGVILTGMGRDGARGLKEIRERGGRTIAQDEASSVVWGMPREAVLMGAAHEVLPLSRIGAALMQWVDVC
What is the function of this protein?
Probable methylesterase (By similarity).  Required for the normal aggregation of M. xanthus cells during fruiting body formation.  It is also a component of a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction.  It may remove the methyl group from the gamma-glutamyl methyl ester residues in FrzCD.
What are the official names of this protein?
Protein-glutamate methylesterase FrzG.
Protein: RM35_CAEBR
Sequence: MFTKAAFSSLCASRHAPISVAVRGIANIPAHEYHIRFDQRVGRKRPAQDVLDRFKRLNNGMWIHAHPGRHKLRYMKDETWQKTSLYYETCTKEQCEILDKLMTPYWLRPKHYPNDPYSAYHVRHNIDSPRVDDRGNFVRERKKVLMDDSTSQRFFKDC
What are the official names of this protein?
Probable 39S ribosomal protein L35, mitochondrial, L35mt, MRP-L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: QUEC_BACSU
Sequence: MKKEKAIVVFSGGQDSTTCLLWALKEFEEVETVTFHYNQRHSQEVEVAKSIAEKLGVKNHLLDMSLLNQLAPNALTRNDIEIEVKDGELPSTFVPGRNLVFLSFASILAYQIGARHIITGVCETDFSGYPDCRDEFVKSCNVTVNLAMEKPFVIHTPLMWLNKAETWKLADELGALDFVKNNTLTCYNGIIADGCGECPACHLRSKGYEEYMVMKGERA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).  Uses ammonia as nitrogen donor.
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: NU107_RAT
Sequence: MDRSGFGGMSSPVIRDPEVTRTARKHSAHKRVLIQANQDENFGTTTPRSQIIPRTPSSFRQPFTPPSRSLLRHPDISYIFGTEGRSPRHIQSSGYLGNLSMVTNLDDSNWAAAFSSQRLGFYTNTEHHSMTEDINLSTVMLREDDPGEAASMSMFSDFLQSFLKHSSTTVFDLVEEYENICASQVNILSKIVSRATRWDWQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSSLEEENMFAIAGINASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGDFSDNIEFYAKSVYWENTLHSLKQRQLLSYIGSTRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLHHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNKYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIRTSVMTLDETEELPREYMEANWTLEKVFEELQATDKKRVLEENQEHYHVVQKFLILGDIDGLMDEFSKWLSKSRSSLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLINEKHTNLIAFYTCHLPQDLAVAQYALFLEGVTECEQRHQCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPSLDTATTEEDRLKIDVIDWLVFDPAQRAEALRQGNAIMRKFLALKKHEAAKEVFVKIPQDSIAEIYNQWEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNERFKHMNSAPQKPTLLSQATFTEKVAHEHKEKKYEMDHNIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAEEDPERAHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQS
What is the function of this protein?
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.  Required for the assembly of peripheral proteins into the NPC.  May anchor NUP62 to the NPC.  Involved in nephrogenesis.
What are the official names of this protein?
Nuclear pore complex protein Nup107, 107 kDa nucleoporin, Nucleoporin Nup107, p105.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin Nup84/Nup107 family.
What are the subcellular locations of this protein?
Nucleus membrane. Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the NPC core structure. During mitosis, localizes to the kinetochores. Dissociates from the dissasembled NPC structure late during prophase of mitosis.
Protein: NU3C_PROM0
Sequence: MFLLTGYEYFLGFLLIAAAVPVLALVTNLIVAPKGRAGERRLTYESGMEPIGGAWIQFNIRYYMFALVFVIFDVETVFLYPWAVAFNRLGLLAFIEALIFIAILVIALAYAWRKGALEWS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3, NDH-1 subunit 3, NDH-C.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: END4_AYWBP
Sequence: MLFLGSHVAMKKPHNFQGSIQTAISYGANALMVYSGAPQNTIRSKTEELKIKEALKIAQNNNLSLNNLVGHAPYIINLANPDKTKRAFAIDFLSQELERFAAMKINKMVLHPGNYLKTNPQEGISLIAQSLDLIFAKTKHLKTQISLETMAGKGTEIGKRLEELQQIRTLVKNKTRVSFCLDTCHLFDAGYDLKENLEEIIQKIDSILGFQNVSVIHINDSKNECNSHKDRHENIGFGKIGFETLLKIIYHRAFVCIPKILETPYINEKEPYKHEIEMIKTKNFNPELKNLF
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: ADDB_CLOBL
Sequence: MSLRFIYGRAGSGKSQYCLNSIKNRIEEDIDRPLILLVPEQFSFQAEKNLIEVLDEKTGFKTQVLSFKRMAYRVFNEVGGITAKHMNESGKSMLLYNIIEDNKNNLKVFKKAAKRQGFITTISDIITEFKRYNITPEIILNNLENIEGDNLKYKMEDLALIFSQFETRLHKNYIDNEDDLTILVEKLNKSKQFDNAEIWIDEFSSFSPQEYSVLEKLLLKSYRINITLCTDYLNQGRFVDTTDVFSPIKNTENKLLQIIEDNNIKLDKPIALKCDPCARFKNSAELQHLEKNMFSFPYKEYKNETKDICMLKTLNQFTEIENTAKDIIKLCIDKGCRFKDIAVITGDLEGYENIISSVFLQYNIPFFIDKKREINNNPIIVLILSALEVLSKNWTYESVFRYLKTGLLDINNEEMDILENYVLANGIKGYQWTNDKPWEHKSFSNYELEDQALKELLAKINDIRYKAMEPIVTLNKNFKSIDKAKEFCEVLYEFLCNINLPDKIQNMIEDFKVEGEIEKASEYNQIWNIVMEVLDQIVEVIGEEKISLKEFFKILQTGFSEYEIGLIPPTLDQVMVGSITRLRSHNINTLYIVGVNDGIFPSPLKEEGILSDDDREFLGDKGLEIAKDTKSIAFEEQFLVYSTLTTPSKYLRLSYPIADGEGKTLRPSIIISRIKKIFANICEENDIVKLNGEEEELKNISSAKPTFNYLISNLRKDVEGVKIDNIWGDTYKWYLENEFWIEKLNRLIKGFDYTNQSKYIETKKIRNLYGKPLKISVSRVEKFSQCPFAYFVQYGLKAKDRKIFNLSYPDLGIFMHSILEKFSHELEKKGLEWDTMDLNWAEEEIDKLINEELDNKSLDILNSSKRYEYVTKSVKKILKRSIWLIGEHIKRGNFKPSYYELSFDIDGDYPPIAMELHSGEVINLIGRVDRVDLLQKDGATYLKIIDYKSGIKEFKLSDVYYGLQLQLLIYLDAILTELAERSGINGEPGALLYLKLDDPIVKNTVDMSDEEIEKSIIKNLKMKGLILNDPNVIRDMDNIISGISDIIPVMVKKDGGVSEGRSSVATKEEFETLRKYVRYTIIEICEEMLEGNIEIKPYKKKDGSSCDYCIYSSVCKFDTNIRGNKYNILIDKKDEEVWDAIKKKLEYKNI
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: GSH1_BORPD
Sequence: MTVTDTAASRLSRLKAHADLLAQSLRGIEKEGLRVDAQGKLAVTPHPSGLGSALTNEHVTTDYSEALLELITGTHGRVEPLLAELENTHRFVYSVLDGEYIWNQSMPATLPPEADIPIAWYGRSNTGMLKHVYRRGLAERYGKAMQCIAGVHYNFSLPDALWEILDPGAADPQTRRSRGYIGLIRNFTRYSWLLMYLFGAAPALSRSFMGDRPHPLQALDADTLYLPHATSLRMSDLGYQNNKAQAQLKLCYNDLDTFLARLYGAVTQPWPEYQAIGTHRDGQWIQLNTNVLQIENEYYSSIRPKRATGRCERPVTALAERGVQYVEVRCLDIDPQQPVGIAADTARFVDAFLLFCAVSDSPYFPQNGYCQRSADNFSVVVKEGRKPGLMLDRDGVAISLPDWGRELLDHIAPYAALYDQALGGDAYARALQAQHAKLGHADDTPSARLLAELRDQGVPFHEYSLQLSRRHADALRAQPLPADVAAGYAEAARQSHAEQARLEQSDDVDFDTYVARYQAALKAPGSR
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: GALT2_DROME
Sequence: MRRNIKLIVFVSIIWMFVMVYYFQSSTEKVENRALRLREVATAMQQYQDDSSSAAAASTARQWAPAGGGAGPGAAAGAAGSGADDPGGNVILIGSVKDFERNAVHGLKLNGIVALEETSQGLSGGTGGPGGRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLELAKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYIGASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAPDPQEVGQFRQDSTECLDTMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEIKHDDLCLTLVTFARGSQVVLKACDDSENQRWIMREGGLVRHYKINVCLDSRDQSQQGVSAQHCNSALGTQRWSFGKYA
What is the function of this protein?
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:12829714, PubMed:18669915).  It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties.  Prefers the monoglycosylated Muc5AC-3 as substrate (PubMed:12829714).  O-glycosylation modification of proteins by this enzyme might be important for cytokinesis (PubMed:20807760).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 2, pp-GaNTase 2, Protein-UDP acetylgalactosaminyltransferase 2, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: DCD_COLP3
Sequence: MRLCDKDIEQYLDDEKIIIEPKPDSSMISGVSVDIRLGNEFRVFQDHTAPYIDLSAPKGEVQEAMNSIMSDEIFIADGDAFFLHPGELALAVTYESVTLPDNIVGWLDGRSSLARLGLMVHVTAHRIDPGWSGQIVLEFYNSGKLPLALRPKMKIAALNFETMSSSAARPYNKREDAKYRDQKGAVASRISQDEKVNK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PURA_DESOH
Sequence: MANIVVVGTQWGDEGKGKIVDLLAAFADLVVRFQGGNNAGHTLVVNGESFISHLVPSGILQGKMCLIGNGVVVDPAVLTEEMAALRSRGVAVIPEKFKVSASAHIIMPYHKTIDLVREEAKGHEKIGTTGRGIGPCYEDKVGRNGLRFVDMLDLPAFREKMARQVKEKNLYLERMFGAAPLDVDGAVAEYVGYAETLAPYIADVSRILADASDEGRQVLFEGAQGTYLDIDHGTYPYVTSSNTVAGNACCGSGIGPRDLSGVLGIVKAYTTRVGEGPFPTELFDDVGDFMQRTGSEFGATTGRKRRCGWLDAVMLKSAARLNGLTGLAITKLDVLTGLDTLEICTAYRYQGKTLSDFPADVKTLSQCEPVYEAVQGWQEDISGVRSAADLPDAARRYLDRITELVGVRVDIVSVGAGRDQTVVINNPFA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OXIR_STRLI
Sequence: MDLTGRRAVVTGGASGLGAETVRALAAAGAEVTIATRHPQSAEPLVQEAAAAGAGRVHAEALDLSDVASVDSFARAWRGPLDILVANAGIMALPTRTLTPYGWEMQLATNYLGHFALATGLHAALRDAGSARIVVVSSGAHLGTPFDFEDPHFARRPYDPWAAYGNSKTADVLFTVGARRWAADGITANALNPGYILTRLQRHVDDETMRAFGVMDDQGNVKPLPYYKTPEQGAATSVLLAASPLLNGVTGRYFEDNQEARTVEDGDVQPGGVAAHALDPEAADRLWEYGADTLSAG
What are the official names of this protein?
Probable oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RHAR_SHIBS
Sequence: MAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFSASAGQPHWRLGSVGMAQARQVIGQLEHESSQHVSFANEMAELLFGQLVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRHLNSQKD
What is the function of this protein?
Activates expression of the rhaSR operon in response to L-rhamnose.
What are the official names of this protein?
HTH-type transcriptional activator RhaR, L-rhamnose operon transcriptional activator RhaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_MOOTA
Sequence: MIIQGKCHTFGNDIDTDAIIPARYLNTTDPGELARHCMEDADPTFAGRVQKGEIIVAGKNFGCGSSREHAPVAIKAAGVAAVVAASFARIFYRNAINIGLPIFESPEAAAGIKAGDEVKIDAGKGEIVNLTRGETYPVAPFPPFMQELIAAGGLMPYVARKVKTSV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: MNME_PARXL
Sequence: MLTTDSDPIVAIATAPGRGGIGVVRISFGRAGEAAAQPLMQALTGQTLAARRASYVPFLDASGDALDRGIALYFPAPHSYTGEHVLELQGHGGPVVLQLVLQRCIDAGRAFGLRLAEPGEFTRRAFLNDKLDLAQAEAVADLIEASTEAAARSAGRSLDGAFSRDIHALVEDVITLRMLVEATLDFPEEEIDFLEAADARGKLARIRERLGHVLSEARQGALLREGLSVVLAGQPNVGKSSLLNALAGAELAIVTPIAGTTRDKVAQTIQIEGIPLHVIDTAGLRDTEDEVEKIGIARTWNEIERADVVLHLLDARTGMTVEDEAIAGRFPAGVPVVRVLNKTDLTGLAPATRALDADLDLSEVRLSAKQGDGVALLREELLRIAGWQAGAESVYLARERHLIALRAAEEHLATAAAHADQNSQALDLFAEELRLAQDQLNSITGEFSSDDLLGVIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.