PharMolix/UniProtQA huggingface dataset:
Protein: FBXW5_RAT
Sequence: MDEGGMPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAATSWYEEFRRLYDMVPCVEVQTLKEHTDQVLHLSFSHSGYQFASCSKDCTVKIWNNDLTISLLHSADMRPYNWSYTQFSQFNQDDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDVTSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTIRTVMVADCSRFDSPDLLLDAGDQAGLPCRVFDLGGDTEEEATDPGLHTSGSGHVKEGLRRVFDSVLDGHGQLSDCALETKVAELLAQGHTKPPECPDADSRNKYLIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDVHGHIIGMGLSPDNRYLYVNSRAWPPGSVVADPMQPPPIAEEIDLLVFDLKTMREVKRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLAKLRHEDVVNSVAFSPQEQELLLTASDDATIKAWRSPRIVRVLQAPHPRPRPFFSWFASHRR
What is the function of this protein?
Substrate recognition component of both SCF (SKP1-CUL1-F-box protein) and DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes.  Substrate recognition component of the SCF(FBXW5) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SASS6 during S phase, leading to prevent centriole reduplication.  The SCF(FBXW5) complex also mediates ubiquitination and degradation of actin-regulator EPS8 during G2 phase, leading to the transient degradation of EPS8 and subsequent cell shape changes required to allow mitotic progression.  Substrate-specific adapter of the DCX(FBXW5) E3 ubiquitin-protein ligase complex which mediates the polyubiquitination and subsequent degradation of TSC2.  May also act as a negative regulator of MAP3K7/TAK1 signaling in the interleukin-1B (IL1B) signaling pathway (By similarity).
What are the official names of this protein?
F-box/WD repeat-containing protein 5, F-box and WD-40 domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the FBXW5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_STAA3
Sequence: MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKNATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GUAAA_METVS
Sequence: MIVILNNGGQYVHRIQRSLKYIGVPAKIVLNSTNLEEIEKNPEIKGIILSGGPDITKATNCENIALNSKLPVLGICLGHQLISKAYGGKVKRAESEEYASIKIHVKYENDIFKNVPNEFTAWASHMDEVKEIPDCLEVLAFSEICGVEAFKHKEKLVYGVQFHPEVSHTEHGELILKNFCKVCGFKFNE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.
Protein: VP4_ROTPY
Sequence: MASLNYRQLLTNSYTVNLSDEIQEIGSAKAQNVTINPGPFAQTGYAPVNWGAGETNDSTTVEPLLDGPYQPTTFNPPTSYWVLLAPTVEGVIIQGTNNTDRWLATILIEPNVQTTNRTYNLFGQQVTLSVDNTSQTQWKFIDVSKTTLTGNYTQHGPLFSTPKLYAVMKFSGRIYTYNGTTPNATTGYYSTTNYDTVNMTSFCDFYIIPRNQEEKCTEYINHGLPPIQNTRNVVPVSLSAREIVHTRAQVNEDIVVSKTSLWKEMQYNRDITIRFKFDRTIIKAGGLGYKWSEISFKPITYQYTYTRDGEQITAHTTCSVNGVNNFSYNGGSLPTDFAISRYEVIKENSFVYIDYWDDSQAFRNMVYVRSLAANLNTVTCTGGSYSFALPLGNYPVMTGGTVTLHPAGVTLSTQFTDFVSLNSLRFRFRLTVGEPSFSITRTRVSRLYGLPAANPNNQREHYEISGRLSLISLVPSNDDYQTPIMNSVTVRQDLERQLGELRDEFNSLSQQIAMSQLIDLALLPLDMFSMFSGIKSTIDAAKSMATNVMKRFKRSNLASSVSTLTDAMSDAASSISRSSSIRSIGSSASAWTEVSTSITDISTTVDTVSTQTATIAKRLRLKEIATQTDGMNFDDISAAVLKTKIDKSAQITPSTLPEIVTEASEKFIPNRTYRVINNDEVFEAGMDGKFFAYRVDTFDEIPFDVQKFADLVTDSPVISAIIDLKTLKNLKDNYGISKQQAFDLLRSDPKVLREFINQNNPIIRNRIENLIMQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: KDPB_YERPE
Sequence: MTHKQRAIFEPALVRTALLDAVKKLDPRVQWRNPVMFVVYLGSWLTTLIWLDILSGHTTGSAMFTGSIALWLWFTVLFANMAEALAEGRSKAQAASLRGVKKTSWAKKLSEARVDAPQEKVSADSLRKGDLVLIEAGDTVPCDGEVLEGGASVDESAITGESAPVIRESGGDFSSVTGGTRVLSDWLVVECRVNPGETFLDRMIAMVEGAKRRKTPNEVALTILLVALTIVFLLATATLYPFSVFSVEASQAGSPVTITVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFLPAPGVTEQQLADAAQLSSLADETPEGRSIVVLAKQRFNLRERDLHSLNATFIPFSAQTRMSGVNVQERMIRKGAVDAIRRHVESNQGHFPPAVDDLVASVARTGGTPLVVAEGSRVLGVVALKDIVKGGIKERFAELRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMQLHSPSSAILSAVIFNALVIVFLIPLALKGVSYKAMSAAALLRRNLWIYGLGGLLVPFVGIKLIDLLLTALNMG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPG_EDWI9
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKTQDRMAASRPYAETMRKVIGHLALGNLEYKHPYLEERDIKRVGYLVVSTDRGLCGGLNINLFKKLLTEMKEWNQKGVDIDLALIGSKAVSFFGSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDRLYVVSNKFINTMSQEPQVIQLLPLPKADDAELKRKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGNLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BL1S1_ARATH
Sequence: MNTPMSLSAARGRMLPFLEKEKSEEESETLESSLLQLIDDNRRSSLQLREKTERSRKEAIRHAARTADLLVKAVNGGVEECFVNEKRIESEIRNLAITVAKFGKQTDQWLAVTHAVNSAVKEIGDFENWMKTMEFDCKKITAAIRNIHEDQQ
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that mediates the vacuolar degradative transport via the intracellular vesicle trafficking from the endosome to the vacuole.  Probably regulates the PIN1 and PIN2 homeostasis through its interaction with SNX1.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 1, BLOC-1 subunit 1, GCN5-like protein 1, Protein RT14 homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome.
Protein: TRPB_SALPK
Sequence: MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: Y447_METJA
Sequence: MNLNIKEIKQKINEWKNREWRWKGKGKIEIRFVCLIERAESFKELVDNLEIIICEYEKIKQLIEDKDIKEIAKLNLFCGNNVYEEMLKDILSSNKFISLTISFDENIAYVKYMERGKEEVVYLDGKSAYKALQILKNRYENILKKQISIIEDAIPLTIPSQ
What are the official names of this protein?
Uncharacterized protein MJ0447.
Protein: RHLR_PSEAE
Sequence: MRNDGGFLLWWDGLRSEMQPIHDSQGVFAVLEKEVRRLGFDYYAYGVRHTIPFTRPKTEVHGTYPKAWLERYQMQNYGAVDPAILNGLRSSEMVVWSDSLFDQSRMLWNEARDWGLCVGATLPIRAPNNLLSVLSVARDQQNISSFEREEIRLRLRCMIELLTQKLTDLEHPMLMSNPVCLSHREREILQWTADGKSSGEIAIILSISESTVNFHHKNIQKKFDAPNKTLAAAYAAALGLI
What is the function of this protein?
Quorum-sensing regulator that controls the expression of multiple virulence factors in response to extracellular signaling molecules called autoinducers (PubMed:7494482, PubMed:8522523, PubMed:15576196).  Involved, among others, in the transcriptional regulation of genes that are responsible for rhamnolipid surfactant biosynthesis (PubMed:8144472, PubMed:7604006, PubMed:14526008).  Acts by binding to a specific sequence in the rhlAB regulatory region, both in the presence and in the absence of its autoinducer (PubMed:14526008).  In the former case it activates transcription of the promoter, whereas in the latter it acts as a transcriptional repressor (PubMed:14526008).  Also regulates the expression of the rmlBDAC operon, encoding dTDP-L-rhamnose biosynthetic enzymes, by binding to the rml box in the promoter region (PubMed:22262098).  In addition, is involved in the regulation of the production of elastase (lasB) and pyocyanine (PubMed:8144472, PubMed:7604006, PubMed:8522523).
What are the official names of this protein?
HTH-type quorum-sensing regulator RhlR, Elastase modulator, Regulatory protein RhlR.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-regulated transcriptional regulatory protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_HALHL
Sequence: MIQMESLLKAADNSGARQVQCIKVLGGSKRRYAGIGDIVKVSVKDAIPRGRVKKGEVYNAVVVRSKRGVRRADGSQIRFDGNAAVLLNNNLQPIGTRVFGPVTRELRNERFMRIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: YEZE_BACSU
Sequence: MGRNKEFDTALVLHRAIEVFGEYGYEGTSLQDLLSHLGIARQSLYDTYGTKRDLFLSAVKSYLEGKNAAVMERLEAPGSVKEAIRDIFQEGVNALRDPERAKACYIINSAIEQIPHDPELARYFERQSKQLEDAFYHGLLRAKDQGELNGEDTDISALARYLNQSRLSLTFIAKVTADMDRLQDHVDVSLSVLD
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YezE.
Protein: RIMM_ACAM1
Sequence: MPVSDSLSPDLPNDDTSEEWLEVGTIVGAHGLNGEVKVYPDSDFPERFTQPGLRWLVSPTEASTPEEIQLIRGRFVERKGIYVVKLANVNFRDQSEALKGTKLLVRSNDRPTLAEGEYYLSDLIGVTVVDHQTQAVVGSVVSLASAGNDLLEIQLDNTTKTILLPFVSALVPIVDIATKRIEITPPKGLIPE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPP2_HUMAN
Sequence: MPVAATNSETAMQQVLDNLGSLPSATGAAELDLIFLRGIMESPIVRSLAKVIMVLWFMQQNVFVPMKYMLKYFGAHERLEETKLEAVRDNNLELVQEILRDLAHVAEQSSTAAELAHILQEPHFQSLLETHDSVASKTYETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRNASGSVILKILPSYQEPHLPRQVFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGSAGLIPSQLLEEKRKAFVKRDLELTPNSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNKLIMWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADVRAGRYLEHGEYEGNLYGTRIDSIRGVVAAGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETLRAMNRAALESGISTKQLTEADLRRTVEESSRIQRGYGHYFDLCLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY
What is the function of this protein?
Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity).  In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression (By similarity).  Seems to negatively regulate SRC function in epithelial cells (PubMed:19665017).
What are the official names of this protein?
MAGUK p55 subfamily member 2, Discs large homolog 2, Protein MPP2.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Membrane. Cell projection, dendrite. Postsynaptic density. Note=Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts.
Protein: RECX_PASMU
Sequence: MISKHCKEAGNHRMSSPALNYVVGLLARREYSEFELRCKMQEKGFSEQEIDDTLAFCQQKNWQNDRRFAENYLTFRAQRGYGFARIKQELQQLKGISSALISEAEQTLAPDWQHHALTVLRKKFPQYAEITDLKLKQKVWRYMLSHGFKPEQFAHYVGHTEYEE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNA14_USTMA
Sequence: MSAEASEAHEAQVKMEVSADQESEIAAVQQIASVGVSADADADADADADADADADADADADADADADADLDADADADADADADADAEADVDHDDKPDAEGDVEVQTDSIAADVKAASENEPAQSANAKMDESQATPQPMAESKLDDHQQQDSQLVSPQAGSSNQPPQPHKYMTVEQRKQLFEERIRIDPRDGEAWLNLIEEAQSREDMAATRALYDRFFKVFPNQARQWLAYLDLELAHSNFAQVEAIFNQCLRTTPSVDLWKFYLSYTRRVNPLAPSTGAEEDPAREQTRRVLEGAYEFALRFIGNDKDSGSIWTDYILLIKEREARGGWKEGQKMDDLRRVYQRAVSVPLTNIETIWKDYDAYENGLNKLTAKKFLAERSPAYMTARRVLRDLKAYSDPLVKPLLPRVPVWTTSALAGDAAQDPAQWQRERQQADAWIEYLKWEESNPLLLEDVAILQARVTSAYRRATMYLRFYPEVWYLASRYLVSILRVDEAATWLKNGMEACPGSFLLHFAYAELGEARKSTSDCAAVFDGLLDHVHAQIDARQAKLQQDLKTVDLEADRTKAQAATRRANEGDGDVDVDGEERERERKAGELLQIRKQELQAAAKPEIEGLKEASALVWIKYMHFLRRTEGIRPARSVFSRARKSPHCTWQVFEASALMEYHCSKDAVVATKVFELALKTFGSDEAFVVRYLDFLISMNDDSNARALFERVIGTFAPERARPIWERWAKYEYNFGDSVAIQKLESRLAETYPDEPATKRFIARSSYMDLDLVGPRDLGIRAAMAGASAADRAVEAAKDGGAEEGPRRKTMQEMKRLAAESAQDDTSGDWARPGASSSAGGAGGPPVKKFKRDSASPAPAAFNNQAVGQQVAGPRDAWNEFPESVLVFMEMLPSAQLFDGPMFKPEDIIDCIRSANVPVGGGARRGAAGYGGAGRGRYR
What is the function of this protein?
Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA 3'-end-processing protein RNA14.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleus and/or cytoplasm.
Protein: PURU_MYCTU
Sequence: MGKGSMTAHATPNEPDYPPPPGGPPPPADIGRLLLRCHDRPGIIAAVSTFLARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQRDFGSTVADKFGIDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIANHPDLAAHVRPFGVPFIHIPATRDTRTEAEQRQLQLLSGNVDLVVLARYMQILSPGFLEAIGCPLINIHHSFLPAFTGAAPYQRARERGVKLIGATAHYVTEVLDEGPIIEQDVVRVDHTHTVDDLVRVGADVERAVLSRAVLWHCQDRVIVHHNQTIVF
What is the function of this protein?
Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
What are the official names of this protein?
Formyltetrahydrofolate deformylase, Formyl-FH(4) hydrolase.
What is the protein family that this protein belongs to?
Belongs to the PurU family.
Protein: DNAK_CAMHC
Sequence: MSKVIGIDLGTTNSCVSVYERGESKIIPNKEGKNTTPSVVAFTDKGEILVGDSAKRQAVTNPEKTIYSIKRIMGLMMNEKNAQEAKKRLPYKIVDRNGACAVEIAGKVYTPQEISAKVLMKLKEDAESYLGEKVVDAVITVPAYFNDSQRKATKEAGTIAGLNVLRIINEPTAAALAYGLDKKESERIVVYDLGGGTFDVTVLETGDSVVEVLATGGNAFLGGDDFDNKLIDYLLSEFKNESGIDIKGDVMAMQRLKEAAENAKKELSSAMETTVNLPFITADQTGPKHLMKTISRAKFEGMIDNLVGETISTLNSVVSDAGLKMSDIKEVVMVGGSTRVPLVCEEVKKAFGKDLNKSVNPDEVVAVGAAVQGAVIKGDVKDVLLLDVTPLSLGIETLGGIMTKLIDKGTTIPTKKSQVFSTAEDNQSAVTINVLQGEREFARDNKSLGNFNLDGIMPAPRGVPQIEVEFDIDANGILTVSAKDKATGKATDIKITGSSGLSDEEIDKMVKDAELHKEDDKKRKESVDARNGADAIAHQTEKTLNEMGEKIPADLRAKIEAALNDLKAVLKDENATKEQIDAKVSALSKTAEEMYKAASAGKNAGGTAGGNGNAGSNGNSGAKKDDDVIDAEVE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RXRG_PONAB
Sequence: MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECASSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
What is the function of this protein?
Receptor for retinoic acid.  Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes.  The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5.  The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).
What are the official names of this protein?
Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CLU_CANAL
Sequence: MSSEEKIEETQQQQQESVPVKELLLKVQLPSFFNVGDDYLTIPSSYEENIADLKQALNIIVLCRNLTNYSILIKGIDIIENFGELITFEQIISHFELDKQEEQEEQGQEREISELKIVIKEKSYNLASIYEQISRFREVIGLHYIDRLSNDIGSCGGVSKFNGIQLDDIKPKEAKKEESTEKEQQEKEELSISKEEVSKISDFAKQFISDSFDGNDFTKLTKFDDINGKVKIPIKSLTISQWSPVPPFQQAKGDLLYLSLQTLEHETFNITCHFSGFFVNKSSTINFNPTIKINEKGKFNKSYLLYDLVCQLSPLFSKTIAENEINLSDSTKYPETYLLPGNSFPAYPWLVNEKDLQNVPDLSRSQLSSLINGVDGADYIKDWNNDIQSIKELPTTTVQERIIREKLIQKSLFEFNKTATETAINIIKGNIPPLNPDESSDKFIYLRNGIFYSSGTSTVNGFENTGGEEASRYVASKDLTGIKLINRHDIRGISSLVTCIVDYMGKRVVCQAPVPGILDTPVITSPTTDAEGKNEAEEPESEPVEKVVYGLSSDGSRILEDKSFEEPLKQIGDFFHLKPHKVQLSSSSSGDDVKTESNLVVSKDTKGLKGTDGRKYVIDLYRTTPRDIEFIEQHFKLDDDHQETSYPHGEALIRHEAVNEWWRRKVAVLFKKETEQLEKEGKLLDKNQDQDQENKPQIAIPTDQVVFNPDAFSSDNENEIEQDREEVREISKFIKEKLIEEFLDEIKDQVIPFDGQQLTDVLHRSGINMRYLGYVAERLVVKKEKHLVDLEELIKENEAKAEKKREEEKEKEEKEATESEDKKEKKEDKEDAEKEEAEAEEEVPTKATYQLTLANYSTLHRIIIQEMISRSVKHILRNLTKSLPSYLISTAIAHFHNCLFGGAINPTPKVDFIDEIYKNFCSKSDLESFIKLTHDDVIKLVSKEVFSRFRYKLSSNWINTIQLPQLFREIAFKYGIQWKSQNYPFTKEEFELQNNQNKETPTQIQIIETKSSKKSKKKTQTQVITEKSIQRSSIFIADDIIGFIPIIKDSSYKSTIVEEIYSNARSHLVQGNKEMGMALFNELLAINESIYGKVNPETAKFYNLVAQVYQELGYDIEAALIGRKAVILCERSCGFDSYDTITAYMNSAYYESSNEQYLNSLKLYKEAMNTWSLVYGKDHPTLINTLTNLSESLLKIKAYDSALELLQEALEITKKLNGEISEITGFIYYRIANIVVTLNKFKESKELFDKAYDIFMKLLGPDDSMTKQVAKYVSSVGLYVEYLKRQQQQQQQETQKKSKTKTKAAPVNNIATTSTSTTKNGKKSKKNNTPPQSNPEIANQSIDEILRFIEGKPSGSKKSNKKK
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Clustered mitochondria protein homolog, Protein TIF31 homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_STAAT
Sequence: MTILSEIVKYKQSLLQNGYYQDKLNTLKSVKIQNKKSFINAIEKEPKLAIIAEIKSKSPTVNDLPERDLSQQISDYDQYGANAVSILTDEKYFGGSFERLQALTTKTTLPVLCKDFIIDPLQIDVAKQAGASMILLIVNILSDKQLKDLYNYAISQNLEVLVEVHDRHELERAYKVNAKLIGVNNRDLKRFVTNVEHTNTILENKKTNHYYISESGIHDASDVRKILHSGIDGLLIGEALMRCDNLSEFLPQLKMQKVKS
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: LRGA_STAAR
Sequence: MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COM_BPMU
Sequence: MKSIRCKNCNKLLFKADSFDHIEIRCPRCKRHIIMLNACEHPTEKHCGKREKITHSDETVRY
What is the function of this protein?
Trans-acting positive regulator required for mom mRNA translation.  Binds the com-mom mRNA 5' and destabilizes a translation inhibition stem to expose mom translation start signals.
What are the official names of this protein?
Translational activator com, Gene product 54, gp54, Gene product com, gpCom.
What is the protein family that this protein belongs to?
Belongs to the com family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: ECNB_ECOL6
Sequence: MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAATKAQQ
What is the function of this protein?
Plays a role in the bacteriolysis.  Is activated under conditions of high osmolarity by the factor sigma S.  Entericidin A functions as an antidote (By similarity).
What are the official names of this protein?
Entericidin B.
What is the protein family that this protein belongs to?
Belongs to the EcnA/EcnB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PYRG_DEHMB
Sequence: MSKFIFVTGGVVSSVGKGITVASLGNILKSRGLSVSVQKLDPYLNVDPGTMSPYQHGEVFVTQDGAETDLDLGSYERFIDIELTADSTVTSGQVYSEVINKERRGDYLGGTIQVVPHVTQEIKARIQRLADRSKADVVIVEVGGTVGDIEGQPFLEAIRQMRNDTGRDNVLYIHVTLLPYIQSTQELKTKPTQHSVNELRRIGIQPDIIVCRADYPISEGIRDKISLFCDVERKAVIFMPTVSTIYEVPLKLESEGVGDLLVSRLHLNASPSDLSVWRGLVEKIKEPTPTVRIALVGKYVELKDAYYSVRESLCHAAIHNGRDIQIDWVHAEDIEKNGPEEYLKHVQGIIIPGGFGIRGIEGMISAVKYARENGIPYLGLCLGMQVMVIEFARYVLGSDKAHSTEFEPDSPYPVIDLLPEQRGVDSKGGTMRLGNYPCVIQPGTMAGQAYGNNLINERHRHRFEFNNDYRDTLSKAGMLFSGLSPDGKLVEICEVTGHPFMMGSQFHPEFLSRPNRPHPLFREFINAAKKVIRDGEQPSLPLSP
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.