PharMolix/UniProtQA huggingface dataset:
Protein: RL13_HELPS
Sequence: MTKTAKVNEIVRDWVVLDAKDKVFGRLITEIAVLLRGKHRPFYTPNVDCGDFVVVINANKVKFSGMKLEDKEYFTHSGYFGSTKSKTLQEMLEKTPEKLYHLAVRGMLPKTKLGKAMIKKLKVYRDDKHPHTAQTSKKDAK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: DHE2_HALSI
Sequence: MTMASKSDSTHDESGDEAADSTEPESALETARRQLYHAASYLDIDQNIVERLKYPKKVHEVTIPIERDDGTVEVFTGYRAQHDSVRGPYKGGLRYHPDVTRDECVGLGMWMTWKCAVMDLPFGGAKGGVAVNPKELSPEEKERLTRRFTQEIRDVIGPNQDIPAPDMGTDPQTMAWLMDAYSMQEGETTPGVVTGKPPVVGGSEGREEAPGRSVAIITQLVCEYYDQPLDETTVAVQGYGSVGANAARLLDKWGATIVAISDVNGAMYEPDGIDTASVPSHDEEPEAVTTYADTVISNEELLTLDVDVLIPAALGNVITKENAEAIAADLVVEGANGPTTSTADSILADRDVAVIPDILANAGGVTVSYFEWLQDINRRAWSLERVNDELEAEMQAAWRAVKDEYENRDVTWRDAAYIVALSRIAEAHEARGLWP
What are the official names of this protein?
NAD-specific glutamate dehydrogenase A, NAD-GDH A.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: PWAP_HALAI
Sequence: LILCVVVCTAAVLGTAAGYESQLPGCPPGAYPAICARYCYSDRDCASGYYCCNTGCLNICVPKPKPGLCPSITQSPCRGNVCNNDQDCPGNRKCCGKPGCKRCYRPKKPGSCPARKYEAGPCVVYCDGDFDCPGDKKCCGGCPRLCEKPCYD
What is the function of this protein?
Inhibits growth of calcium carbonate crystals.  May inhibit growth of certain crystallographic planes in the mineral phase of nacre in the shell (By similarity).
What are the official names of this protein?
Perlwapin.
What are the subcellular locations of this protein?
Secreted.
Protein: TDF1_TUBDR
Sequence: MSFKTRAVAESTYYIKSGAYYLAVTPERQIITQNTVYAWEVSIEGEYNYLKDPGTTHYLTDNGGQNLLNPRSDVDGKWGGGSEDQATQLINAETEKPLSVPYGQPFQTWLFVKV
What is the function of this protein?
May play a role in the structure of the hypha-forming fruit bodies.
What are the official names of this protein?
11.9 kDa wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: FTSZ1_THEKO
Sequence: MLKLIEDAIERTSAAPQASAPEVRTQSDIDEELKKLLEQIQAKIYVVGVGGAGCNTINRMMQVGIQGAKIIAMNTDAQDLLKVRAHKKILLGKELTRGLGAGNNPKIGEEAAKESEREIREALEGADMVFITCGLGGGTGTGAAPVVAEIAKKMGALTVAVVTLPFTVEGIRRIKNAEYGLERLKKNTDTVIVIPNDKLMEVAPNLPIHMAFKVADEILVQAVKGITELITKPGLVNLDFNDVRAVMKDGGVAMIGIGESDSEKRALEAAQQALNSPLLDVDISGAKGALISISGSDVKLEEAQQIIELVTSKLDPEAQVIWGIQLDEELGKMIRILLVVTGVSSPYSVAEEEEESYFGEEERRPIKLDLDEL
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ 1.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: PURA_CAMJ8
Sequence: MSKADIIVGIQWGDEGKGKVVDKLCENYDFVCRSAGGHNAGHTIWVNGVRYALHLMPSGVLHPRCINIIGNGVVVSPEVLIAEMAQFENLKGRLYISDRAHLNLKHHSLIDIAKEKLKGKNAIGTTGKGIGPSYADKINRTGHRVGELLEPQRLCEALMKDFEANKTFFEMLEIEIPSAEELLADLKRFNEILTPYITDTTRMLWKALDEDKRVLLEGAQGSMLDIDHGTYPYVTSSSTISAGALTGLGLNPKEAGNIIGIVKAYATRVGNGAFPTEDKGEDGEKIAQIGKEIGVSTGRKRRCGWFDAVAVRYTARLNGLDALSLMKLDVLDGFEKIKICRAYEYKGMEIDYIPSDLENVQPIYEEMDGWDKVFGIKDYDLLPENAKKYIARLEELAGVKVKYISTSPERDDTIIL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB2_TROWT
Sequence: MRGKRMNHITVSGLVATEPRSFLTAEGVHITSFRLAAQDRHFSRNANSWVSGDTNWFTVTGFRALGSNAAESISKGDRVIVYGRLRLRTWGDNKMAVEIEAESFGHDLRWGTSVFSKRFYQLPEASDNLRTKYDVDEAETPEIHAKAA
What are the official names of this protein?
Single-stranded DNA-binding protein 2, SSB 2.
Protein: HTPG_ECO57
Sequence: MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_OCEIH
Sequence: MNELKQKYQDEIVSSLMDKFNYNSVMEVPKVEKIVINMGVGDAVQNSKALDSAVEELSLISGQKPMITRAKKSIAGFRLREGMPIGAKVTLRGERMYEFLQKLVAVSLPRVRDFRGISKKAFDGRGNYTLGVKEQLIFPEINYDKVSKIRGMDIVVVTTSNTDEEARELLAQLGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y1051_METJA
Sequence: MILGICDGHNASSSLIKRDEILFAMSEERFTRKKNQRGFPEKSVDYILNKVKPDEINYVSVGGVFRRGERIKKLKEFQNRINKKFLYFYHHISHSYLFKLSDFKEALVISIDGGGDGLSFLASIANKNNLEIIAQSDLIDSVGDFYASITELLGFKPMEDEGKVMSLSSYEGEDDINLTTIDYIKELKSFKNYLGVIGYEATKALKKLIVSDKSQLSFEDKVRISKFAQRTLENIVLKAIDDLSNEYNIDNIVFVGGVAQNVKLNSKIAEKYNLFVPPFMGDEGLCLGASLADKRIDRININNTYFGYEIENERAEKILEELKNKLNDYKIEFVEERDIPEVIGNLILDNKVVCLSRGKMEFGPRALGNRSVIALPTKENKEKINKKLKRSWFMPFAPTILYDFIDDYLINPRYSPFMTQIFKVKENKIKEIEGVIHVDKTTRPQTLKKDSNKTFYGIIRYIYDSIGIPVVLNTSFNLHGEPIVCNEKDAINSFLKADFDALLLGNYLISKVK
What are the official names of this protein?
Uncharacterized protein MJ1051.
What is the protein family that this protein belongs to?
Belongs to the NodU/CmcH family.
Protein: PPARG_CRIGR
Sequence: MVDTEMPFWPTNFGISSVDLSMMDDHSHSFDIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKAQLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQLLHVIKKTETDMSLHPLLQEIYKDLY
What is the function of this protein?
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids.  Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase.  It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.  Key regulator of adipocyte differentiation and glucose homeostasis.  ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer.  Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated pro-inflammatory responses.  Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of BMAL1 in the blood vessels.
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Redistributed from the nucleus to the cytosol through a MAP2K1/MEK1-dependent manner. NOCT enhances its nuclear translocation (By similarity).
Protein: DRS7_PITHY
Sequence: GLWSTIKQKGKEAAIAAAKAAGQAALGAL
What is the function of this protein?
Has antibacterial activity against the Gram-negative bacterium E. coli and the Gram-positive bacterium S. aureus (PubMed:16844081).  Has antiprotozoal activity against L. amazonensis (PubMed:16844081).  Has antifungal activity (By similarity).  Has no hemolytic activity (PubMed:16844081).
What are the official names of this protein?
Dermaseptin-H7, DRS-H7, DShypo 05.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL13_METI4
Sequence: MKTYFQKPQEVQRKWYIIDARDKIVGKVAEKVACLLRGKHKEVFSPHVDTGDHVIVINASKAIFSGKKETQKLYSAYSGYIGGQKTFSPVQIRQKRPNFIIEHAVRGMIPHNRLGRKIYTKLHVYEGSDHPHAAQKPIPVTLD
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TIG_CHLT2
Sequence: MSSRDFSNDLFSINIEENAGCVVSAKVQANPLVTQKCHKEALKTVKKNVVLPGFRKGKAPDNIVESRYSTQVEQELRRLFLRASFEALSQMCDRKPLSPKAVRSSAIDTCNPVNGGSVSFLYEAFPVIPSLPWEQLSLPDPEPVKEISEEDLENGLKNVAYFFATKTPVTRPSQEGDFISLSLYVSKRGDENSTPVAIFENKYFKISEEDMTDSFKARFLNVSTGHRVEEEIGSEDIQSFLNGDLLTFTVNAVIEISSPEMDDEKARELQAESLEDLKKKLRIQLENQAKEAQHQKRFSDAEDALAQLIDFDLPESLLREREELLSREKLLNARLVKYCSDSELEEQKQALLEEAKADARKAVKLLFLTQKVFSEKGLSISREELQYMMDVCSRERFGGYPPKDISNEMIQELVLVARDRLTYRKAIEAISSEKKDLEVVPS
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL35_RHOPA
Sequence: MPKLKTKSGAKKRFKVTATGKVMSAQRGKRHGMIKRTKKQIRQLRGTRAIFKTDGDNIKKYFLPNA
What are the official names of this protein?
50S ribosomal protein L35, RRP-L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: HLDD_RALPJ
Sequence: MTIIVTGAAGFIGANIVKGLNERGETDIIAVDNLTRADKFKNIVDCQISDYLDKTDFVERFARGEFGKVRAIFHEGACSDTMETDGRYMMDNNYRYSLAVMRACLDQGVQFLYASSAATYGASETFREEPEFERPLNVYGYSKLLFDQVVRRVMLTALSQIVGFRYFNVYGPREQHKGRMASVAFHNFNQFRSEGTVKLFGEYNGYPQGGQMRDFVSVEDVVKVNLFFFDNPDKSGIFNLGTGRAQPFNDIATTVMNTLRGAEGKPALSTEELAQEGLIEYVKFPDALRGKYQCFTQADQSRLRAAGYTAPFLTVQEGVERYCQWLLKQPV
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: CP2D6_HUMAN
Sequence: MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids (PubMed:18698000, PubMed:19965576, PubMed:20972997, PubMed:21289075, PubMed:21576599).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:18698000, PubMed:19965576, PubMed:20972997, PubMed:21289075, PubMed:21576599).  Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA) (PubMed:19965576, PubMed:20972997).  Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyeicosatrienoic acid ethanolamides (EpETrE-EAs), potentially modulating endocannabinoid system signaling (PubMed:18698000, PubMed:21289075).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Metabolizes cholesterol toward 25-hydroxycholesterol, a physiological regulator of cellular cholesterol homeostasis (PubMed:21576599).  Catalyzes the oxidative transformations of all-trans retinol to all-trans retinal, a precursor for the active form all-trans-retinoic acid (PubMed:10681376).  Also involved in the oxidative metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
What are the official names of this protein?
Cytochrome P450 2D6, CYPIID6, Cholesterol 25-hydroxylase, Cytochrome P450-DB1, Debrisoquine 4-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: PTH_BURO1
Sequence: MIKLIVGLGNPGAEYTATRHNAGFWLIDQLAREAGTTLRDERRFHGFYAKARLHGEEVHLLEPQTYMNRSGQSVVALAQFFKILPDQILVAHDELDLPPGTVKLKLGGGSGGHNGLKDITAHLSSQQYWRLRIGIGHPRDLISESARAGAKPDVANFVLKPPRREEQDVIDASIERALAVMPMVVKGELDRATMQLHRN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
Protein: PURL_PROM2
Sequence: MINQENNDLYDLNEALKVENLTLNDYEEICKRLKRKPNRTELGMFGVMWSEHCCYRNSKPLLSKFPTEGKHVLVGPGENAGVIDVGNNQKLVFKIESHNHPSAIEPFQGAATGVGGILRDIFTMGARPIAVLNSLRFGNLDKSSNVDLLRGVVSGIAHYGNCVGVPTVGGEIDFDDSYSGNPLVNVMALGLLETEEIVCSGAKNVGSPVLYVGNTTGRDGVGGASFASSELTTTSLDDRPAVQVGDPFIEKSLIEACLDAFKTGDVIAAQDMGAAGLTCSSAEMAANGKLGISIDLDLVPSREDDMSSYQYLLSESQERMLFVVKEEKINDLIEKFSKWGLYASVVGEVIGTNEVIISHKGKIVAKIPTSALSDDTPVNFHNVINNPPDDLLKKWEWKENDLPEIHEKNIFSLKENKNFSFSEIILKLLSNPSIASKRWIYKQYDSQVQSNTVFTPGKSDAAVIRLREQNKKNKSKVFSGVAASVDCNSRWVALDPFRGSIAAVAESARNVSCVGAEPVAITNNLNFSSPENEIGYWQLSSSCNGIAEACKALETPVTGGNVSLYNESKNKDNLITPINPTPVIGMVGKLDNVEKAISSEWKNIEDQIWLIGSHKSETKIAASSYLEYFHGEITGRPPKIDLLDEKFCQSFLRNAILKSLVVSSHDISDGGLAIALAESCILSERGATIELEKDLNRVDNLLFAEGGSRIIFTISKMKQNEWFNYLQLNQIKFPSSVYVKKIGYVSSDTLKIKIDEKNICNIRVEELTEKFNNSISDYF
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMI1_MEDTR
Sequence: MAKSNEESSNLNVMNKPPLKKTKTLPSLNLRVSVTPPNPNDNNGIGGTSTTKTDFSEQQWNYPSFLGIGSTSRKRRQPPPPPSKPPVNLIPPHPRPLSVNDHNKTTSSLLPQPSSSSITKQQQQHSTSSPIFYLLVICCIILVPYSAYLQYKLAKLKDMKLQLCGQIDFCSRNGKTSIQEEVDDDDNADSRTIALYIVLFTLILPFVLYKYLDYLPQIINFLRRTESNKEDVPLKKRVAYMVDVFFSIYPYAKLLALLCATLFLIAFGGLALYAVTGGSMAEALWHSWTYVADAGNHAETEGTGQRIVSVSISAGGMLIFAMMLGLVSDAISEKVDSLRKGKSEVIERNHVLILGWSDKLGSLLKQLAIANKSVGGGVIVVLAEKEKEEMEMDIAKLEFDFMGTSVICRSGSPLILADLKKVSVSKARAIIVLAADENADQSDARALRVVLSLAGVKEGLRGHVVVEMSDLDNEPLVKLVGGELIETVVAHDVIGRLMIQCALQPGLAQIWEDILGFENAEFYIKRWPELDDLLFKDILISFPDAIPCGVKVAADGGKIVINPDDNYVLRDGDEVLVIAEDDDTYAPGPLPEVRKGYFPRIRDPPKYPEKILFCGWRRDIDDMIMVLEAFLAPGSELWMFNEVPEKERERKLAAGELDVFGLENIKLVHREGNAVIRRHLESLPLETFDSILILADESVEDSVAHSDSRSLATLLLIRDIQSRRLPYRDTKSTSLRLSGFSHNSWIREMQQASDKSIIISEILDSRTRNLVSVSRISDYVLSNELVSMALAMVAEDKQINRVLEELFAEEGNEMCIKPAEFYLFDQEELCFYDIMIRGRTRKEIVIGYRLANQERAIINPSEKSVPRKWSLDDVFVVLASGE
What is the function of this protein?
Required for early signal transduction events leading to endosymbiosis.  Acts early in a signal transduction chain leading from the perception of Nod factor to the activation of calcium spiking.  Also involved in mycorrhizal symbiosis.  May be involved in the regulation of the calcium channel responsible for calcium spiking by mobilizing another cation, and thereby altering the membrane potential.
What are the official names of this protein?
Ion channel DMI1, Does not make infections protein 1.
What is the protein family that this protein belongs to?
Belongs to the castor/pollux (TC 1.A.1.23) family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein.
Protein: MDTI_KLEP7
Sequence: MQQFEWIHAAWLAIAIVLEIIANVFLKFSDGFRRKIYGILSLAAVLGAFSALSQAVKGIDLSVAYALWGGFGIAATIAAGWVLFGQRLNNKGWAGVILLVAGMVLIKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLT11_CRYNJ
Sequence: MPAKHDINKVGVESSDFPILCETCLGPNPYVRMNKQEFGHECKVCNRPFTVFRWNPGEGRMKKTEICTTCAKIKGVCQTCLLDLEFGLPTQVRDAALARKAQAPSSDINKQYYIQNLEAQMAESPDGLAYDSEVANRAGREMLKNLARTDPYYKRNRPHICSFFVKGECKRGAECPFRHEMPKENETQKPSQQSLVDRYYGRNDPVAKKILSQNAESKGLKAPEDKSITTLLFLGLPQCNDSHVRASLVGACPFVKPSDVKSISIVEASHCAFVNFNQRSMAERAADALAAQGGIEVEGKKAKIVWGRARPQKKAAAAVEGSAAPA
What is the function of this protein?
Involved in pre-mRNA splicing.  Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome.  Binds to RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor SLT11.
What is the protein family that this protein belongs to?
Belongs to the SLT11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAN7_PIG
Sequence: MDAAALERDAVQFARLAVQRDHEGRYSGAVFYYKEAAQALIYAEMAGSSLEHIQEKINEYLERVQALHSAVQSKSADPLKSKHQLDLERAHLLVTQAFDEDEKGNVEDAIELYTEAVDLCLKTSYETADKTLQNKLKQLARQALDRAEALSEPLTKPLCKVKATNIKPKPPPTRTHFPLGTNPFQEGPQPFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMNIDLRERFAYPMPFCDRCGKLPLSPKQKAMFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFTKKLITSIIYPQNKDGESEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYQRFHKGDVLITASTGVMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTPQKIDNGIFWISWDDLCQYYDVIYLSWNPGLLKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTVSKQINGKWSGQSAGGCGNFQETHKNNPIYQFHIEKSGPLLIELRGPRQYSVGFEVVTVSVVGDPGPHGFQRKSSGDYRCGFCYLELESIPAGIYNIIPSTFLPKQEGPFFLDFNSVIPIKTTQLQ
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease.
What are the official names of this protein?
Calpain-7.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPTSB_MOUSE
Sequence: MDFKRVKEYFAWLYYQYQIITCCAVMEPWEQSMLNTIILTIVAMVVYTAYVFIPIHIRLAWEFFSKICGYDSSISN
What is the function of this protein?
Stimulates the activity of serine palmitoyltransferase (SPT).  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for longer acyl-CoAs.  The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference.
What are the official names of this protein?
Serine palmitoyltransferase small subunit B, Protein ADMP, Small subunit of serine palmitoyltransferase B, ssSPTb.
What is the protein family that this protein belongs to?
Belongs to the SPTSS family. SPTSSB subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ACPS_BRUC2
Sequence: MIVGIGSDLIDIRRVEKTLERHGSRFRDRVFTEIEQRKSEGRKQRAASYAKRFAAKEACAKALGTGIAEGVFWRDMGVVNTPSGKPTMHLTGGAAKQLQKLLPAGTNAAIHLTITDDFPLAQAFVIIEALPVLE
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFSD5_BOVIN
Sequence: MLVTAYLAFVVLLASCLGLELSRCRAKPSGRACSNPSFLRFQLDFYQVYFLALAADWLQAPYLYKLYQHYHFLEAQIAILYVCGLASTVLFGLVASSLVDWLGRKKSCVLFSLTYSLCCLTKLSRDYFVLLVGRALGGLSTALLFSAFEAWYIHEHLERHDFPTEWIPATFARAAFWNHVLAVAAGVAAEAVACWMGLGPVAPFVAAIPLLALAGALALHNWGENYDRQRAFSRTCAGGLRCLLSDRRVLLLGTIQALFESVIFIFVFLWTPVLDPHGAPLGIIFSSFMAASLLGSSLYRIATSKRYHLQPMHLLSLAVLIVVFSLFMLTFSTSPGQESPVESFIAFLLIELACGLYFPSMSFLRRKVIPETEQAGVLNWFRVPLHLLACLGLLVLHDSDRKTGTRNMFSICSAVMVMALLAVVGLFTVVRHDAELRVPSPTGEPYTPEL
What is the function of this protein?
Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
What are the official names of this protein?
Molybdate-anion transporter, Major facilitator superfamily domain-containing protein 5, Molybdate transporter 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.