PharMolix/UniProtQA huggingface dataset:
Protein: FTHS_CERS4
Sequence: MAVQTDIEIARAARKKPIQEIGAGLGIPAEALIPYGHDKAKVGQGFIRGLEGRPDGKLILVTAINPTPAGEGKTTTTVGLGDGLNRIGKKAVICIREASLGPNFGMKGGAAGGGRAQVVPMEDMNLHFTGDFHAITAAHNLLAAMIDNHIYWGNALELDARRITWRRVMDMNDRALRDTVVNLGGVANGFPRQTGFDITVASEVMAILCLADDLEDLERRLGRIVVGYRRDKSPVYCRDLKAAGAMAVLLKDAMQPNLVQTIENNPAFVHGGPFANIAHGCNSVIATRTALKLADYVVTEAGFGADLGAEKFFDIKCRLAGLKPSAAVVVATVRALKMNGGVAREDLGREDVAALRRGCANLGRHIANVKGFGVPVVVAINHFTTDTEAEIEAVRAYAAGQGAEAFLCRHWAEGSAGIEDLAQKVVELAETPSMFAPLYPDDMPLFEKMETVARRIYHAHDVIADHVIRDQLRTWEEAGYGALPVCMAKTQYSFTTDAAIRGAPEGHSIPIREVRLAAGAGFVVAICGEIRTMPGLPSQPAAELIHLDEEGRIEGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: GSA_CORU7
Sequence: MASTNTNVNAAAEERHHESAAAMERARRFIPGGVNSPVRAFGSVGGTSPFITSASGSQLQDADGLSYVDLVCSWGPMIHGHAHPEIVEAVKSTASRGLSFGAPTSLEVDLAEEIVNRTSVEKVRLVNSGTEATMSAVRLARGFTGRDKILKFEGCYHGHVDSLLVAAGSGVATFGLPDSPGITKAAASDTVVVPYRDIEAVKKAFAENEGQIAAIITEATPGNMGTVSSITADGTSFNAQLKEIAHANGALLIVDEVMTGFRVGYQGWFGKDGVAGDLTTFGKVVSGGLPAAAFGGRADIMDHLAPVGPVYQAGTLSGNPVAMASGLASLKLADEDAYRTLDANAERLIGLITEALNRESVEHHIQRAGTMFSVRFADGEGTNFGEMKAADTFRYPAFFHELLDNGIFAPPSVFETWFVSTALTDADFERFEAALVPAAKAAAAAEA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_SPHAL
Sequence: MTPLNQVEGRAIPLGLKNIDTDVIIPAHWLKTTTREGMGRGAFESLRADPDNLFDRPEYRQAPILIAGDNFGCGSSREHAAWALGDLGIRVVIAPSYSDIFSGNAVKNGILPVVLPQAAIDRLLEVAATDPVRIDLEHQTVTTPFQDRFTFEIDPFRKMCLLEGLDEISLTEKSDAAIGAYEDRLDAERPWMRAVVG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PEPX_RHOBA
Sequence: MTKLVRSRLDLTWVFTTMKRLRLPVLAVLFLAISPVQGGEIQIPVIKDGEAQVIKELEDSDYWIRHDLWVETEFDLDGDGKLDRMHVSVTRPTQTDTQSLKLPVIYNSSPYFAGTTGGDESYFWDARQELGDEPPKRSAAPAIEREGTRPIISKRHVKDWLPRGFVVVHSSAPGTGLSQGCPTVGDDPEALAPKAVIDWLCGRAKGFTEPFGGEPVEAYWSSGKVGMTGTSYNGTIPLAAATTGVEGLEVIIPVAPNTSYYHYYRSNGLVRHPGGYLGEDIDILYDFIHSGGDEETRAYCDCHIRDEQMMANQDRATGDYNDFWYSRDYLNRVDGVKAAVLMAHAFNDWNVVPEHSIRIYEALKKNGVETQLFMHQGGHGGPPPISMMNRWFTHYLYGEDNGVEKGSKSWIVREKDERTKPTEYPQYPHPEAKDVVVYPVPGAPQRGRLQTAPLTEPITETLVDNFSFAGETLAQAEYTEHRLIYTTPELSEAVHLSGTPRIKLRLACDRPAANLSVWLVSLPWNTQKNSKITDNIITRGWADPQNIESMRESKPLVPGQFYDIEFDLQPDDQVIAKGQQIGLMVFSSDRDYTLHPTPGTKLTIDLQHTQLSLPVVGGTIPLESQD
What are the official names of this protein?
Putative Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
Protein: RNH2B_RAT
Sequence: MAGGRDRGDLAARQLVFLLPEYLKDASRKSKSGLLFVKLVNPHSGEGATYLIDACLQKLFEIKVFKEKHHSWFINQSVQSGGLLHFATPMDPLFLLLHYLIKAGKEGKYQPLDQVVVDDKFPDCTLLLRFPELEKSLRHVTEEKEVNSKKYYKYSTEKTLKWLEKKVNQTVAALKANHVNVGARVQSSAYFSGVQVSRDKEEDYVRYAHGLISDYIPKELSDDLSKLLKLPEPPASLPNPPAKKLKLADEPVEAKEDYTKFNTKDLKNGKKNSKMTAAQKALAKVDKSGMKSIDAFFGAKNKKTGKI
What is the function of this protein?
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids.  Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication.  Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity).
What are the official names of this protein?
Ribonuclease H2 subunit B, RNase H2 subunit B, Ribonuclease HI subunit B.
What is the protein family that this protein belongs to?
Belongs to the RNase H2 subunit B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SDHD_OENOB
Sequence: MTETLLKKKLNLNDQFLLNLKNYQEIFWKNPNYGDELPDLDVNRETIFQANRRLERFAPYLESVFSDTKRSKGIIESPIQRMDSIKDLLSVKGSLLIKRDDLMPVSGSIKSRGGIYEVLCFAEKIAIENGFDLKKDNYQDLRKDKYRKLFNQWRIEVASTGNLGLSVGLMASTLGFKARIHMSHDATDWKINKLLQNGVEVKIYDDNFSNAVAAARVSSQRDPYSYFIDDEGSKLLFAGYATAGERVKKQLSKMQIEVSKEHPLVVYLPAGVGGSPSGVAFGLKLQFADAVIPIFVEPTHMPSVLLGMASGLNHDISVYDIGIDGKTAADGLAVGRPSMIAGKYMKDKLFGIATVSDSDMFAYQGMLKKLENIEVEPSAAVGIRGLIQSKEISEIPDSATHMVWATGGSMVPKNTMHKYEDKAVRIFNTWKSE
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: PI21_ORYSI
Sequence: MGILVISVDLQCCRCDAKIRKVLGCLEEEYCIEKVEYDVKNNRVIVRGKFDPEKLCKKIWCKAGKIIKEILIVDVWPPPLPPPCKPPPCEKPPEDCKPKPCHCCSCEKPKPKPKPCHCEKPKPCHCEKPKPCEKPPPCKPEEPPKPPPEKPPPKPECKLVPYPYPVPYPYAGQWCCPKPEPPKPPPEPPKEPEPPKPCGCSHAFVCVCKPAPPPPPPCGCSGGHGNCGCGIRPWPPQVWPPPPVCPPPPWCYTEDNANACSIM
What is the function of this protein?
Involved in defense responses.  Contributes to slowing defense responses toward Magnaporthe oryzae.
What are the official names of this protein?
Protein PYRICULARIA ORYZAE RESISTANCE 21, Pi21.
Protein: HMT2_ARATH
Sequence: MTGNSFNSMKDFLKQTGGYAVIDGGLATEFERHGADLNDPLWSAKCLVTSPHLIHTVHLDYLEAGADIISSASYQATIQGFEAKGFSREESESLLKKSVEIATEARNSYYDKCGTSSSMDDKILKKRPILVAASVGSYGAYLADGSEYSGIYGDSITLEKLKDFHRRRLQVLAESGADLIAFETIPNKIEAQAFADLLEEGDVKIPGWFSFNSKDGVNVVSGDSIKECISIAENCEKVVAVGINCTPPRFIEGLVLEIEKVTSKPILVYPNSGESYDADRKEWVENTGVGDEDFVSYVEKWMDAGVSLLGGCCRTTPTTIRAIHKRLVNRRSL
What is the function of this protein?
Catalyzes methyl transfer from S-methylmethionine (SMM) to adenosyl-L-homocysteine (AdoMet).  SMM degradation (by HMT-1, HMT-2 and HMT-3) and biosynthesis (by MMT1) constitute the SMM cycle in plants, which is probably required to achieve short term control of AdoMet level.
What are the official names of this protein?
Homocysteine S-methyltransferase 2, S-methylmethionine:homocysteine methyltransferase 2, AtHMT-2, SMM:Hcy S-methyltransferase 2.
Protein: GATB_STAS1
Sequence: MHFETVIGLEVHVELKTDSKMFSPAPAHFGAKPNSNTNVIDLAYPGVLPVVNRRAVDWAMRASMALNMEIATESKFDRKNYFYPDNPKAYQISQFDQPIGENGYIDIEVDGETKRIGITRLHMEEDAGKSTHKDGYSLVDLNRQGTPLIEIVSEPDIRSPQEAYAYLEKLRSIIQYTGVSDCKMEEGSLRCDANISLRPYGQEEFGTKAELKNLNSFTYVRKGLEYEEKRQEEELLNGGEILQETRRFDESNGKTLLMRVKEGSDDYRYFPEPDIVPLYVDEEWKERVRQTIPELPDERKEKYVNQYGLPAYDAHVLTLTKEMSDFFEGAVAEGADVKLTSNWLMGGVNEYLNKNQIDLLDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPELAENGGDAKQIMEDKGLVQISDEATLLKFVNEALDNNEQSIEDYKNGKGKAMGFLVGQIMKASKGQANPQLVNQLLKQELDKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: ITM2C_BOVIN
Sequence: MVKISFQPAVAGIKGDKADKASASASASAPAPTPAAEILLTPAREERPPYQRYKKGGSVGGVCYLSMGMVVLLMGLVFASVYIYRYFFLAQLARDNFFHCGVLYEDSLSSQAHTRMELEEDVKIYLEENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFWELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCSGKDTYRLRRRATRRRINKREAKNCNAIRHFENTFVVETLICGVV
What is the function of this protein?
Negative regulator of amyloid-beta peptide production.  May inhibit the processing of APP by blocking its access to alpha- and beta-secretase.  Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor.  May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
What are the official names of this protein?
Integral membrane protein 2C.
What is the protein family that this protein belongs to?
Belongs to the ITM2 family.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass type II membrane protein. Cell membrane; Single- pass type II membrane protein.
Protein: VAC14_MOUSE
Sequence: MNPEKDFAPLTPNIVRALNDKLYEKRKVAALEIEKLVRDFVAQNNTMQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESSKFDLVSFIPLLRERIYSNNQYARQFIISWILVLVSVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDEPDEPKSVAQKQTEPNPEDSLPKQEGTASGGPGSCDSSFGSGINVFTSANTDRAPVTLHLDGIVQVLNCHLSDTTIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVVLKDLEVLAEIASSPAGQTDDPGAPDGPDLRVNHSELQVPTSGRANLLNPPSTKGLEGSPSTPTMNSYFYKFMINLLQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILLTSTELFQLRNQLKDLQTPESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDCLKAAPKSQKGDSPSIDYTELLQHFEKVQKQHLEVRHQRSGRGDHLDRRVIL
What is the function of this protein?
Scaffold protein component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Pentamerizes into a star-shaped structure and nucleates the assembly of the complex.  The pentamer binds a single copy each of PIKFYVE and FIG4 and coordinates both PIKfyve kinase activity and FIG4 phosphatase activity, being required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P).  Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
What are the official names of this protein?
Protein VAC14 homolog.
What is the protein family that this protein belongs to?
Belongs to the VAC14 family.
What are the subcellular locations of this protein?
Endosome membrane. Microsome membrane. Note=Mainly associated with membranes of the late endocytic pathway.
Protein: RS3_RHOP5
Sequence: MGQKINPIGLRLGINRTWDSRWFAGKNEYGKLLHEDVKIRAILHKELKQAAVARIVIERPHKKCRVTIHSARPGVVIGKKGADIDKLRKKVADITASDVVINIVEIRKPELDATLVAESIAQQLERRVAFRRAMKRAVQSAMRLGAEGIRINCSGRLGGAEIARMEWYREGRVPLHTLRADIDYGVATAFTTFGTCGVKVWIFKGEILEHDPMAQDKRMAEGDNSRPRRDAA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PANB_PROM1
Sequence: MQTTDLVRFKKLGKQITVLTAWDAISSSIVEAAGADVVLVGDSLGMVVLGHSTTLPVTLDQMLHHTKAVCRGFCRPLSKQPLVVCDLPFLSYQCGEDKAVEAAGTLLKNSTASAVKLEGAEPETLLVIKRLIRMGIPVMGHLGLTPQSVHQLGYKSQARDKDSQEKIFKDSKMLQESGCFAIVLEHIPAEIASRLKKHIDIPVIGIGAGSDCDGQVRVTADILGLSIAQPPFAKPLLAGRELCINALKEWINSTDLDQVNPTTKTSESKSDC
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PD_HUMAN
Sequence: MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
Protein: TX18A_CYRSC
Sequence: MKLSLIIIATSLVIAVVAFPSKDSAATDFDKTESLENVEERVETALDERPRACSKNPGESCTNNCECCGATVVCASVYVAGVEKKSCKSKTSDNGFLNIIGQAANAVQNAASLCV
What are the official names of this protein?
U7-theraphotoxin-Hs1a, U7-TRTX-Hs1a, HWTX-XVIIIa1, HWTX-XVIIIa2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 25 family. F7 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPX_STRCO
Sequence: MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAETSEVRWEELPKPREIYEFLESYVVGQEAAKKALSVAVYNHYKRVQAGENGGAQGREDAIELAKSNILLLGPTGSGKTLLAQTLARMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQIDTTNVLFIVGGAFAGLEKIIEGRAGAKGIGFGAQIRSKREIESKDQFEQVMPEDLVKFGMIPEFIGRLPVITSVHNLDREALLQILVEPRNALVKQYERLFELDGVELDFERGALEAIADQAILRQTGARGLRAIMEEVLQGVMYEVPSRKDVARVVITADVVLSNVNPTLIPRDSRGRGPGEQKTA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PGLR_EMENI
Sequence: MFYALGPLALFAFATEVMATPVAYPMTTASPTLAKRDSCTFSGSDGAASASRSQTDCATITLSDITVPSGTTLDLSDLEDDTTVIFEGTTSWEYEEWDGPLLQIKGNGITIKGADGAKLNPDGSRWWDGEGSNGGVTKPKFFYAHDLTDSTIQNLYIENTPVQAVSINGCDGLTITDMTIDNSAGDDAGGHNTDGFDIGESSNVVITGAKVYNQDDCVAVNSGTSITFSGGTCSGGHGLSIGSVGGRDDNTVDTVTFKDSTVSNSVNGIRIKAKSGETGEIKGVTYSGISLESISDYGILIEQNYDGGDLDGEVTSGIPITDLTIENISGSGAVDSDGYNIVIVCGDDACSNWTWSDVEVTGGEDYGSCENVPSVASCST
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase AN8327, Pectinase AN8327, Polygalacturonase AN8327.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPA_WOLSU
Sequence: MNTVTGAMSALITPFRNGRLDTETYEKLIQRQIRHGMDALVPVGTTGESATLSHSEHKECIEIAVKVCQGTGIKVLAGAGSNSTLEAIDLAKFAEKMGADGILCVTPYYNKPSQEGLFQHYKAVAESVGIPLMLYNVPGRTGVNLETCTIQRLFNEVKNIYGIKEASGSMERIVELNTKIPDFAILSGEDAINYPVLANHGVGVISVIGNLLPDKISALVHKALQGELDESRRINNSLYKINKALFVESNPIPIKAAMYLAGLTPTLEYRLPLVSPSQENMRMIEETLKDYEVKA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_LACP7
Sequence: MKKILFVASESVPFIKTDGLADVVGSLPKYINKNNFDIRVILPNYMSIPRQWKEKMLYRTHFYMNLNWRTQYVGVLEYQYEGIWYYFIDNEFYFAGNKPYGNIYEDIEKFAFLSKAVLTCLPVLDFRPDIIHCHDWQTGLVPVFLHDSFQKNEFYHGIKTIMTIHNLKFQGVWDKKTVQDITALSEYYFSPDKLETYGDANYLKGGIVFSDYITTVSDTYAHDITMPFYGEGLDGLMRARSDCLCGIVNGIDYEEYNPEFDPFINKPYNAKNFRKEKIKNKRALQQELGLAKDDKAFMIGIVSRLIDQNGLDLIDCVMEDICAEDTQLIILGTGKDRYENLFRHYARKYSSRVSANIFYSNEQSHKIYAACDAFLMPSLFEPCGLSQLMSLRYGTVPIVRETGGLVDTVEPYNQHESTGTGFTFKNYNAHEMLYTIRFAKEIYQDKKREWNKIIDRGMAKDFSWKTSARKYEELYESL
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RS17_METS4
Sequence: MPKRVLQGVVVSDKQDKTIVVKVERRFTHPVMKKTVRRSKNYHAHDENNAAKVGQTVFIEESRPFSKLKTWRLVEGEARDVAATEA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ILVC2_BACHK
Sequence: MKTYYEQDANVGLLQGKTVAVIGYGSQGHAQAQNLRDSGVEVVVGVRPGKSFEVAKADGFKVMSVSEAVRTAQVVQMLLPDEQQAHVYKAEVEENLREGQMLLFSHGFNIHFGQINPPSYVDVAMVAPKSPGHLVRRVFQEGNGVPALVAVHQDATGTALHVALAYAKGVGCTRAGVIETTFQEETETDLFGEQAVLCGGVTALVKAGFETLTEGGYRPEIAYFECLHELKLIVDLMYEGGLTNMRHSISDTAEFGDYVTGSRIVTDETKKEMKRVLTEIQQGEFAKKWILENQAGRPTYNAMKKAEQNHQLEKVGEELREMMSWIHAPKELVKK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)) 2, KARI 2, Acetohydroxy-acid isomeroreductase 2, AHIR 2, Alpha-keto-beta-hydroxylacyl reductoisomerase 2, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: Y577_HAEIN
Sequence: MLYTFSQSDYPKTELDDYFSYITEKDAVVLWQDGVLLAIKYPDYFAKCKGNCMILKQDILARNLTALLPQSSKIKLISIEELVGITENYLPQLSL
What are the official names of this protein?
Uncharacterized protein HI_0577.
Protein: RL19_NEIM0
Sequence: MNLIQQLEQEEIARLNKDIPEFAPGDTVVVSVRVVEGTRSRLQAYEGVVIARRNRGLNSNFIVRKISSGEGVERTFQLYSPTVEKIEVKRRGDVRRAKLYYLRGLTGKAARIKEKLPARKG
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: URE2_PARMW
Sequence: MAPLIPGELLPEPGELELNAGRPVTTLSVANSGDRPVQVGSHFHFAEANAALQFDRTAARGQRLDIPAGTAIRFEPGDSRDVNLIPFAGNRRVIGFNGQINGPLDA
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1433S_MOUSE
Sequence: MERASLIQKAKLAEQAERYEDMAAFMKSAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVKEYREKVETELRGVCDTVLGLLDSHLIKGAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADSAGEEGGEAPEEPQS
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.  May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
What are the official names of this protein?
14-3-3 protein sigma, Stratifin.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=May be secreted by a non-classical secretory pathway.
Protein: SYD_CLOP1
Sequence: MGEALNGLKRNIMCGDARESHIGQKVTVMGWVQRNRNLGGLQFIDLRDREGILQVVFNDDLGEEILEKAKSIRPEYCIAVTGEIVKRESVNPNMPTGMVELKAEELKILSESDTPPIYIKEDLDAAESIRLKYRYLDLRRPDMQNIFKIRHKTTKAIRDYLDQNGFLEMETPILTKSTPEGARDYLVPSRNYPGMFYALPQSPQLFKQLLMVSGFDRYFQIVKCFRDEDLRANRQPEFTQVDLEMSFVEQDDVMALNEGLIKHVFKEVLGVDVKTPIKRMTFKDAMEKYGSDKPDLRFGMEITNLSDVVKECGFKVFTDAVANGGSVRGLCLEGGASMGRKDIDRLGEFVKTFKAKGLAWIQLKEEGVKSPIAKFFSEEELNKIIETMGAKTGDLILIVADKNSVVLKALGELRLELSRKFDLVKDKSEFNFTWITEFDLLEYDEEEGRYFAAHHPFTMPMDEDIKYLDTDPGRVRAKAYDLVLNGEELGGGSIRIHDTKLQEKMFEVLGFTQESAWERFGFLLEAFKFGPPPHGGLAFGLDRMIMFLAGTENIKDVITFPKNQNAFCYLTEAPNIVDEEQLKELGIETIKKEDTAE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK16_CUSRE
Sequence: MLSPKRTRFRKQHRGKMKGISYRGNHICFGKYALQALEPAWITSRQIEAGRRAMTRKARRGGKFWVRIFPDKPVTVRPAETRMGSGKGCPEYWVAVVKPGRILYEMGGVTKNIARRAFSIAASKMPIRTQFIILEIE
What are the official names of this protein?
50S ribosomal protein L16, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid.
Protein: RS19_HELPG
Sequence: MSRSIKKGPFIDDHLMKKTLKAKEGKDNRPIKTWSRRSTILPEMIGFTYNVHNGRVFVPVYITENHVGYKLGEFAPTRTFKGHKGSVQKKIGK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL17_AFIC5
Sequence: MRHGKVHRKLNRTAEHRKAMFANMAASLIKHEQIVTTLPKAKELRPIVEKLVTLGKKGGLALRRQAISELRDHDQVKKLFDALAARYKDRQGGYTRIIKAGFRYGDNAPMAVIEFVDRDVDAKGQDSGPVQEKADSEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: NADA_SALA4
Sequence: MSVMFDPQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSPAKTILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCWQGACIVHDEFKTQALTRLKKIYPDAALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPEKELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAHEIQVDAALREGALLPLNRMLDFATTLRA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF4EB_DANRE
Sequence: MASCAVQLIDKVPKKKVEKKKFEPNILKEPCMKHPLQNRWGLWFYKNDKSKMWQDNLRLITKFDTVEDFWGLYNNIQLPSKLSSGCDYSMFKDGIEPMWEDRSNKCGGRWLITLAKQHRHTELDHFWLETLLCLIGEGFSSFSRDICGSVINIRAKGDKIALWTSNAENCETVTYIGRKYKESLGLPQKLVIGYQAHADTATKSNSITKNKFVV
What is the function of this protein?
Does not appear to be a mRNA-cap-binding protein.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-1B, eIF4E, eIF4E-1B.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.