PharMolix/UniProtQA huggingface dataset:
Protein: PO4F1_MOUSE
Sequence: MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAGGGGGAHDGPGGGGGPGGGGGPGGGGPGGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHGLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY
What is the function of this protein?
Able to act as transcription factor, cannot regulate the expression of the same subset of genes than isoform 1 (PubMed:12934100).  Does not have antiapoptotic effect on neuronal cells (PubMed:9722627).
What are the official names of this protein?
POU domain, class 4, transcription factor 1, Brain-specific homeobox/POU domain protein 3A, Brain-3A, Brn-3A, Brn-3.0.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y1421_ENT38
Sequence: MSTYSRPVLLLLCGLLLLTLAIAVLNTLVPLWLAHENLPTWQVGMVSSSYFTGNLLGTLLTGKLIKRFGFNRSYYLASLIFAAGCVGLGLMVGFWSWMTWRFIAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTVLGQLMISKLPTDLMSVLPWVTGMVLAAILPLLFTRIVNQGSEHHEATQVWPMLRLRHARLGVNGCIISGIVLGSLYGLMPLYLNHQGVSDSGIGFWMAVMVSAGIVGQWPIGKLADRYGRLLVLRVQVFVVILGCLAMLGNAAMAPALFILGAAGFTLYPVAMAWACEKVENHQLVAMNQALLLSYTIGSLLGPTFTAMLMQNYSDNLLFIMIASVAFIYLLMLLRKAGEHPTPVAHA
What are the official names of this protein?
Uncharacterized MFS-type transporter Ent638_1421.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL13_ACIET
Sequence: MSTFSAKPAEVVHEWFVIDATDKVLGRVASEVALRLRGKHKAIYTPHVDTGDYIVIINASKLKVTGTKSLDKVYYRHSGYPGGITATNFRDLQAKHPGRALEKAVKGMLPKGPLGYAMIKKLKVYGGAEHPHTAQQPKALEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MTRB_METJA
Sequence: MATYVFIDQNIPLVYTVETGVITKGFGDLLFVDVSPIEEQIKKLETLVDAYEHSLDPRYPPLNSFPNRDGVYAISGYFKSAFFGFWIGLGIMALLAIILGVKF
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit B, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B.
What is the protein family that this protein belongs to?
Belongs to the MtrB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL5_RHORT
Sequence: MARLQEHYQTVVKKALLEKFQYGNVMEIPRLEKIVINMGVGEASQDRKLIEGALTDMTAISGQKPIITRAKKSIAAFKLREQMIVGCKVTLRRDRMFEFLDRLVTIALPRVRDFRGVSAKSFDGRGNYNMGLKEQIVFPEIDYDRVDKVRGMDITICTSAKSDEEAKALLEGFAMPFMK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PAC1_PSESV
Sequence: MNAPVPVPRVADFTCEKKPATGSRGMVVTNHPLASAAGAQILLAGGNAIDAAVASLFALTVAEPMMVGILGGGLSHIRLADGRHVVIDNLSTAPGKATADMYECLSDEIGKQRDTRDRENVVGAKAVAVPGALKGWCEALARFGTLPLAEVLQPAIGLAERGFVVTPYLSNCITDNAADLARDPGLAAMLLPGGQPLQPGMRLIQSDYAASLKLIAAEGPEALYGGKLGRALTDYMAANGGLIDQADLSNYRIELREPIRGSYRGYEIIGPPPPSSSGVHIAQMLNILEGYDIGALGFGSTDAVHLLAEALKIAFADRAVATADPAFVKVPVARLIDKAYADERRALIAMEQAKSWTAGLSGGESADTTHVTVADAMGNVVSATQTINGLFGACVQTPGTGMIANNYMYNFDPHPGRALSIAPGKRVFTSMAPMMAVKEGRLAFALGLPGALRIFPSALQAIVNLIDHRMSLQEAVEAPRVWTEGGVLELEEAIPESVAQALIARGHKVVRSPRVAGGMNAIAFNPDGTLTGAACWRADGTPVAISGGLARAGARFTI
What is the function of this protein?
Besides the cephalosporin acylase I activity which converts GL-7ACA into 7-ACA; this enzyme displays some gamma glutamyltranspeptidase activity.
What are the official names of this protein?
Acylase ACY 1 proenzyme.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
Protein: BTUC_ECOL5
Sequence: MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGELWILPGDWFSPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGEISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: XERC_RICPR
Sequence: MLDISIQELIKQWQKYLILQKNYSNNTVIAYNNDLKHFLEFMNYYNSELVTLNHIKTADIRLIRSWLAKRKCENFTASSIARGLSTVKNFYKFLEKTLLLNNHIIFSIKSPKKAKLLPKGLSVDDVLISLEHIEEYGNVKWVELRNKALIVLIYAAGLRISEALSITKLHLQNLEFIKIIGKGSKERIIPWLPLTKNLITKYLEILPYKLDENEPIFRGRQGKKLQPSVFNRELIKLKRIYGLPEYLTAHSFRHSFASHLLEYGADLRSIQELLGHKSLSTTQKYTQTSIKHLEAVYNTAYPIKK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids (By similarity).
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHUT_PSHV1
Sequence: MGILGMRRFIREHELSVHLSIQMERGLYIPIAVDTWNVLTPIMRRLDPGNMMDPVERTLRGIMQVFSLLNKKSCFPIFVLDGGRKRAFKGPVKHDYHNIDHRAPTDGDDLEASANENQPHSLAGNAPRLASGARGAHQSSRRKTALRATPHYKLCWDLITASGFPTVYVKGMEADYGCANLFHTKTVMYVWSSDSDMVFMGCDVITDLTPAFPVAVFSKHVLEYLNMTQREFANTFVDCHTNLHSPETIYSFAAKLLEHRCGSAIDEPPAASEESSASDQQSADEDEHGAWSRYTRRPPRRADAAAWGAGPGGNGQLKGVSVLCGFPSDARPFDCAPARRRRLPQRREEPAARLKKNREFLAYMNSFIGCKVINNRHTLIKRVPIRQETFDPVEIYRILHEYAPTMANKWCAEMLVKCKLKPVPPLRDVAYGKATQINLC
What is the function of this protein?
Minor structural protein that acts as an endoribonuclease during lytic infection.  Degrades host mRNAs in the cytoplasm by cutting them at preferred sites, including some in regions of translation initiation (By similarity).
What are the official names of this protein?
Virion host shutoff protein, Vhs.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae VHS protein family.
What are the subcellular locations of this protein?
Virion.
Protein: NRDR_MANSM
Sequence: MHCPFCSTEETKVIDSRLVSDGYQVRRRRECTKCHERFTTFETAELVVPKIIKNNGMREPFNEDKLRRGIQHALEKRPVSADDVEKAISHITHQLRATGEREVPSKLVGSLVMEELKKLDKVAYIRFASVYLSFENINEFSNEIEKLKD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: Y1685_STAA3
Sequence: MDWILPIAGIIAAIAFLILCIGIVAVLNSVKKNLDYVAKTLDGVEGQVQGITRETTDLLHKVNRLTEDIQGKVDRLNSVVDAVKGIGDSVQTLNSSVDRVTNSITHNISQNEDKISQVVQWSNVAMEIADKWQNRHYRRGSANYKANNVATDANHSYTSRVDK
What are the official names of this protein?
UPF0478 protein SAUSA300_1685.
What is the protein family that this protein belongs to?
Belongs to the UPF0478 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYGB_ENT38
Sequence: MSDKTFLVEIGTEELPPKALRSLAESFAANVTAELDNAGLTHGKIEWFAAPRRLALKVANLAASQADREVEKRGPAISQAFDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESAEALLPNMIATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDTVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPQILLERGKVIADYELRKAKIKADAEEAARKIGGNADLSESLLEEVTSLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPIQIISGNEKVVRPRLADAEFFFNTDRKKRLEDHLPRLQTVLFQQQLGTLRDKTDRIAELSGWIAREIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACAVAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLSLDLQTLTEEAVRLYGDKLTNAKVVDEVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEAASALAAANKRVSNILAKSDETLNERVNAATLKEPEEIALALQVVVLRDKLEPFFAEGRYQEALVELAELREVIDAFFEKVMVNVEDKDLRINRLSMLEKLRELFLRVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TO6BL_DROME
Sequence: MDRTTVVPSPASTYCSFMGGSQHSPLRRSQRLIDKENRDLQKIPPKSLSPQLFGNTEDDYSELLLQQGKVVHLKPAAKLVPVRSSDNLVHLGSRDKVVPLKTSNRIVHLKPPYKIIHLKSLDEVEKTVKKKNNIQKEVHQRNSQRRSIQCTPKKRGRKPKQPAKKLQSRISTDQLGSTPSPSKLPAKYPAHFVHQLPPAEDSSCATRRRSLSAPAMQLSDLSLTPDEIQTPERRGEIVNKSPSDLDSDVSLNFSLSDSIGEIFGTKDISSILTMQRPRQYILLEEHLPTLATMLNVDLERLRCVLDITQGLSHEQILRFPIKHEEDELEVP
What is the function of this protein?
Required for formation of the mei-W68-mediated double-strand breaks (DSBs) that initiate meiotic recombination.
What are the official names of this protein?
Meiotic recombination protein P22.
What is the protein family that this protein belongs to?
Belongs to the TOP6B-like family.
What are the subcellular locations of this protein?
Chromosome. Note=Localizes to foci on meiotic chromosomes.
Protein: MNMA_BACAN
Sequence: MNKLPHETRVVIGMSGGVDSSVAALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKQYWDKVFTYFLDEYRAGRTPNPDVMCNKEIKFKAFLEHAIALGADYVATGHYARVAYMDGEYKMLRGVDDNKDQTYFLNQLSQEQLSKTMFPLGELKKPQIREMAKEAGLATAAKKDSTGICFIGERNFKDFLSNYLPAQPGVMQTLSGEVKGKHDGLMYYTIGQRHGLGIGGNGDPWFAVGKNLKENILYVDQGFHNELLYGDEVIATNVGWVSNEAKEKEFKCTAKFRYRQEDNKVTVQIVDENTVRILCDEPIRAITPGQAVVFYDGDECLGGATIDEVYRSGKKLDCLG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IQCN_HUMAN
Sequence: MTLQGRADLSGNQGNAAGRLATVHEPVVTQWAVHPPAPAHPSLLDKMEKAPPQPQHEGLKSKEHLPQQPAEGKTASRRVPRLRAVVESQAFKNILVDEMDMMHARAATLIQANWRGYWLRQKLISQMMAAKAIQEAWRRFNKRHILHSSKSLVKKTRAEEGDIPYHAPQQVRFQHPEENRLLSPPIMVNKETQFPSCDNLVLCRPQSSPLLQPPAAQGTPEPCVQGPHAARVRGLAFLPHQTVTIRFPCPVSLDAKCQPCLLTRTIRSTCLVHIEGDSVKTKRVSARTNKARAPETPLSRRYDQAVTRPSRAQTQGPVKAETPKAPFQICPGPMITKTLLQTYPVVSVTLPQTYPASTMTTTPPKTSPVPKVTIIKTPAQMYPGPTVTKTAPHTCPMPTMTKIQVHPTASRTGTPRQTCPATITAKNRPQVSLLASIMKSLPQVCPGPAMAKTPPQMHPVTTPAKNPLQTCLSATMSKTSSQRSPVGVTKPSPQTRLPAMITKTPAQLRSVATILKTLCLASPTVANVKAPPQVAVAAGTPNTSGSIHENPPKAKATVNVKQAAKVVKASSPSYLAEGKIRCLAQPHPGTGVPRAAAELPLEAEKIKTGTQKQAKTDMAFKTSVAVEMAGAPSWTKVAEEGDKPPHVYVPVDMAVTLPRGQLAAPLTNASSQRHPPCLSQRPLAAPLTKASSQGHLPTELTKTPSLAHLDTCLSKMHSQTHLATGAVKVQSQAPLATCLTKTQSRGQPITDITTCLIPAHQAADLSSNTHSQVLLTGSKVSNHACQRLGGLSAPPWAKPEDRQTQPQPHGHVPGKTTQGGPCPAACEVQGMLVPPMAPTGHSTCNVESWGDNGATRAQPSMPGQAVPCQEDTGPADAGVVGGQSWNRAWEPARGAASWDTWRNKAVVPPRRSGEPMVSMQAAEEIRILAVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWRGYSTRRDQARHWQMLHPVTWVELGSRAGVMSDRSWFQDGRARTVSDHRCFQSCQAHACSVCHSLSSRIGSPPSVVMLVGSSPRTCHTCGRTQPTRVVQGMGQGTEGPGAVSWASAYQLAALSPRQPHRQDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGHHTRSCLKNTEALLGPADPSASSRHMHWPGI
What is the function of this protein?
Essential for spermiogenesis and fertilization (PubMed:36321563).  May be required for manchette assembly in elongating spermatids (By similarity).
What are the official names of this protein?
IQ domain-containing protein N.
Protein: ACCA_GLUDA
Sequence: MRQFLDFEKSVAELENKIDELRKMSEPDGINLAEEIARLTDKSEKQLRAAYAKLSPWQKVQVARHAQRPHAADYIGTLIQDFTPLAGDRLFGEDKAVIGGIGRFQNQPVVVIGTERGSELESRLAHNFGMARPEGYRKAQRLMELAGRFGMPILTFIDTSGAWPGIDAEARGQAEAIARSIDTCLSAPVPVIATVIGEGGSGGAIALGAGDRVMMLEHAIYSVISPEACASILWRDPKQATSAAEALKLTAQDLLQLKLIDRIIPEPVGGAQRDPESTIRSVGDSIAAELPDLLSLSAPMLVAQRREKFLAMGRDSLS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAJQ_SALCH
Sequence: MPSFDIVSEVDLQEARNGVDNAVREVESRFDFRGVEATIELNDANKTIKVLSESDFQVNQLLDILRAKLLKRGIEGASLDVPDEFVHSGKTWYVEAKLKQGIESAVQKKIVKLIKDSKLKVQAQIQGEEIRVTGKSRDDLQSVMALVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: ASSY_SERP5
Sequence: MQNQGIKKIVLAYSGGLDTSAIIPWLKENYGGCEVVAFVADIGQERSDLEGVEQKALQSGASECHVVDLREEFIRDYVYPVLQTGALYEGSYLLGTSMARPIIAKAQVELALKVGADAVCHGATGKGNDQVRFETTYTALAPHLKVVAPWREWNLRSREALLDYLKERNIPTTASLEKIYSRDENAWHISTEGGVLESPWNAPNKDCWVWTVDPQEAPDQPEQVTITVEKGCVVAVNGEALSPYKCLETLNVLGAKHGVGRIDIVENRLVGIKSRGCYETPGGTIMVAALRGVEQLVLDRDSFKWREQLGLEMSYVVYDGRWFAPLRRSLQASAEALAEEVNGEVVLQLYKGQVTAIQKKSANSLYSEEFATFGEDEVYDHSHAGGFIRLFSLSSRIRALNEIKNK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUPO_BACSU
Sequence: MEYVIEMLNIRKAFPGIVANDNINLQVKKGEIHALLGENGAGKSTLMNVLFGLYQPERGEIRVRGEKVHINSPNKANDLGIGMVHQHFMLVDTFTVAENIILGKEPKKFGRIDRKRAGQEVQDISDRYGLQIHPEAKAADISVGMQQRAEILKTLYRGADILIFDEPTAVLTPHEIKELMQIMKNLVKEGKSIILITHKLKEIMEICDRVTVIRKGKGIKTLDVRDTNQDELASLMVGREVSFKTEKRAAQPGAEVLAIDGITVKDTRGIETVRDLSLSVKAGEIVGIAGVDGNGQSELIEAVTGLRKTDSGTITLNGKQIQNLTPRKITESGIGHIPQDRHKHGLVLDFPIGENILLQSYYKKPYSALGVLHKGEMYKKARSLITEYDVRTPDEYTHARALSGGNQQKAIIGREIDRNPDLLIAAQPTRGLDVGAIEFVHKKLIEQRDAGKAVLLLSFELEEIMNLSDRIAVIFEGRIIASVNPQETTEQELGLLMAGSTQKEAGKANG
What is the function of this protein?
Part of an ABC transporter complex involved in the uptake of guanosine (PubMed:21926227).  Responsible for energy coupling to the transport system (Probable).  May be a nucleoside transporter of broad specificity but with various affinities for different substrates (PubMed:21926227).
What are the official names of this protein?
Guanosine import ATP-binding protein NupO.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RSMH_LYSSC
Sequence: MFDHTTVLLKETVDGLNIDPDGVYVDCTLGGAGHSEYLVQQLSDKGRLICFDQDMTAIENAKIRLAPYIERVTFIHSNFRYLKEELLAHGFEQVDGILYDLGVSSPQLDTPERGFSYHHDAPLDMRMDQTATLTAFEVVNQWAYEDLVRIFFRYGEEKFSKQVARKIEEARKSAPIETTGQLVELIKEGIPAAARRKGGHPAKRIFQAIRIAVNDELGAAEDSLVDAIDMINVGGRISVITFHSLEDRLCKTIFKEASSLPELPPNLPVIPDDMKPTLKLITRKPIVPSDEELEVNNRARSAKLRVVEKINDKGRE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCRI_PARDE
Sequence: MSHADEHAGDHGATRRDFLYYATAGAGTVAAGAAAWTLVNQMNPSADVQALASIQVDVSGVETGTQLTVKWLGKPVFIRRRTEDEIQAGREVDLGQLIDRSAQNSNKPDAPATDENRTMDEAGEWLVMIGVCTHLGCVPIGDGAGDFGGWFCPCHGSHYDTSGRIRRGPAPQNLHIPVAEFLDDTTIKLG
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
What are the official names of this protein?
Ubiquinol-cytochrome c reductase iron-sulfur subunit, Rieske iron-sulfur protein, RISP.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RLMKL_MANSM
Sequence: MKELFATTARGFEELLKLELSSLGATECQVAQGGVHFMADDETQYRALLWSRLSSRILLPIVKTKIYSDLDLYSAVVRQNWLAYFDERVRFLVDFNGTNREIRHTQFGAMRVKDGIVDYFERNGKARPNVDKDYPDIRIHAYLNRDDLVLSLDLSGEALHLRGYREDSGAAPLRETLAAAIVLRSGWKQGTPLVDPMCGSGTLLIEAAQMEAKIAPQLHRMHWGFDFWRGHNQAAWEKVKREAVAMAEAEFNKNPNPHFYGFDLDHRVLQKAQRNAQNAGVAHLIKWKQGDVAALKNPTPEDKGTVICNPPYGERLGTTPALIALYSVFGQRLKEQFPGWNASIFSSEQGLLDCLRMRSHRQFKAKNGPLDCIQKNYQISDRTLSPENKSAVENAGEFKPNANVATDFANRLQKNIKKIEKWAKQEGIEAYRLYDADLPDYNLAVDHYGDHIVVQEYAAPKNIDENKARQRLLDAVTATLAVTGVETNKLILKVRQKQKGANQYEKLANKGEYFYVNEYGAKLWVNLTDYLDTGLFLDHRLTRRMVGQMAKGKDFLNLFAYTGSATVHAALGGAKSTTTVDMSNTYLNWAEQNLILNEADGKQHKLIQADCLQWLANCAQQFDLIFVDPPTFSNSKRMEDSWDVQRDHIKLMGNLKRILRPNGTIVFSNNKRGFKMDFEGLTRLGLKAEEISAKTLPLDFERNKQIHNCWIVEFV
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COS_DROME
Sequence: MEIPIQVAVRIFPHRELKDLLRSFGPTEPKKDAQAVDEGADSKDSEAQVPAAEKDNPSISETDPNGNAEQDSAADSKTIPDANGNDSGQKDYPDSAYCVQAIPISASALGLPSALPGGDPMDSIAAGLIQVGPHTVPVTHALPSSSSQEQVYHQTVFPLITLFLEGFDASVVTYGQRGQGKSYTLYGNVQDPTLTDSTEGVVQLCVRDIFSHISLHPERTYAINVGFVEICGGDVCDLLGMGNIHCTNVDAVFHWLQVGLSARQSLPAHTLFTLTLEQQWVSKEGLLQHRLSTASFSDLCGTERCGDQPPGRPLDAGLCMLEQVISTLTDPGLMYGVNGNIPYGQTTLTTLLKDSFGGRAQTLVILCVSPLEEHLPETLGNLQFAFKVQCVRNFVIMNTYSDDNTMIVQPAEPVPESNSSAGPLSQAGPGDNFGLQFAASQWSKLVTNAEGLFSKLIDSKLITEVEKEQIEEWLFLKQECEECLSSTEAMRQQKQLVPILEAEEPEDVNSEAANSESPNSDNENDTDNESHRPDLDDKIESLMEEFRDKTDALILEKHAEYLSKHPKAVMQSQDREIEAQPPEENGDDRKVSIGSRRRSVQPGASLSTAELAMLNRVASQQPPPPIDPESVVDPLESSSGEGIRQAALAAAAATAPIEQLQKKLRKLVAEIEGKQRQLREIEETIQVKQNIIAELVKNSDTRSHAKQRFHKKRAKLEAECDKAKKQLGKALVQGRDQSEIERWTTIIGHLERRLEDLSSMKHIAGESGQKVKKLQQSVGESRKQADDLQKKLRKECKLRCQMEAELAKLRESRETGKELVKAQGSPEQQGRQLKAVQARITHLNHILREKSDNLEEQPGPEQQETLRHEIRNLRGTRDLLLEERCHLDRKLKRDKVLTQKEERKLLECDEAIEAIDAAIEFKNEMITGHRSIDTSDRIQREKGEQMLMARLNRLSTEEMRTLLYKYFTKVIDLRDSSRKLELQLVQLERERDAWEWKERVLSNAVRQARLEGERNAVLLQRQHEMKLTLMLRHMAEETSASSASYGERALAPACVAPPVQASSDFDYDHFYKGGGNPSKALIKAPKPMPTGSALDKYKDKEQRSGRNIFAKFHVLTRYASAAAAGSSGSTAEESTALIESTTTATATTTSTTTTGAVGKVKDKALVSFRPEQLKRLMPAPTATKVTRQKNKIIIQDASRRN
What is the function of this protein?
Regulates cubitus interruptus (ci) processing by recruiting multiple kinases to promote its efficient phosphorylation.  Scaffolds multiple kinases and ci into proximity to promote its hyperphosphorylation, which then targets it for SCFSlimb/proteasome-mediated processing to generate its repressor form.  Hh signaling inhibits ci phosphorylation by interfering with the cos-ci-kinases complex formation.  Negatively regulates hh-signaling pathways during various processes, including photoreceptor differentiation (PubMed:25639794, PubMed:27195754).  May negatively regulate a hh-signaling pathway which functions in the intestinal immune response to bacterial uracil by activating the Duox-dependent production of reactive oxygen species (ROS) (PubMed:25639794).
What are the official names of this protein?
Kinesin-like protein costa, Kinesin-like protein costal2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF27 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HOA2_MYCSJ
Sequence: MSTKDIFFNPIWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFSKTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHFGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVAALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQDSGATAAH
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 2, HOA 2, 4-hydroxy-2-keto-pentanoic acid aldolase 2, 4-hydroxy-2-oxopentanoate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: SHO1_ASPFU
Sequence: MAKFRASNILGDPFALATVSISILAWLIACIASIISDIKTDYPNYSWWAVAYMFCCIMGVTIVFGSDTGLVYGVAVVGYLSTGLVLTTLAVNSLVYADESSSQAAAAGFILMSMVIVVWIFYFGSSPQATHRGFIDSFALNKESSGAYGNRPMSTAYGPRPDTMSTSAPQMYTSAQLNGFETSSPVSGYPGGGPGSENRSSSQARFGNPSASNVAGNNSGQDEVPPPTEYPYKAKAIYSYDANPEDANEISFSKHEILEVSDVSGRWWQARKSNGETGIAPSNYLILL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.  Regulates radial hyphal growth and germination.  Involved in virulence and mediates resistance to oxidative stress.
What are the official names of this protein?
High osmolarity signaling protein sho1, Osmosensor sho1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LHDAG_HDVIT
Sequence: MSRSESRKNRGGREEILEQWVAGRKKLEELERDLRKTKKKLKKIEDENPWLGNIKGILGKKDKDGEGAPPAKRARTDQMEVDSGPRKRPLRGGFTDKERQDHRRRKALENKKKQLSAGGKNLSKEEEEELRRLTEEDERRERRVAGPPVGGVIPLEGGSRGAPGGGFVPSLQGVPESPFSRTGEGLDIRGNRGFPWDILFPADPPFSPQSCRPQ
What is the function of this protein?
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging or budding.  Packages the HDV ribonucleoprotein in hepatitis B virus empty particles.  Interacts with both HDV genomic RNA and cytoplasmic tail of HBsAg.  May inhibit viral RNA replication (By similarity).
What are the official names of this protein?
Large delta antigen, L-HDAg, p27.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=isoprenylated in the cytoplasm, and translocates in the nucleus possibly after phosphorylation. Translocates after to nuclear speckle, then to the ER membrane where interaction with Hepatitis B virus antigene takes place (By similarity).