PharMolix/UniProtQA huggingface dataset:
Protein: EFTU_ACIB3
Sequence: MAKAKFERNKPHVNVGTIGHVDHGKTTLTAAIATICAKTYGGEAKDYSQIDSAPEEKARGITINTSHVEYDSPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGPMPQTREHILLSRQVGVPYIIVFLNKCDLVDDEELLELVEMEVRELLSTYDFPGDDTPVIRGSALAALNGEAGPYGEESVLALVAALDSYIPEPERAIDKAFLMPIEDVFSISGRGTVVTGRVEAGIIKVGEEVEIVGIKDTVKTTVTGVEMFRKLLDEGRAGENCGILLRGTKREEVQRGQVLAKPGTIKPHTKFDAEVYVLSKEEGGRHTPFLNGYRPQFYFRTTDVTGAIQLKEGVEMVMPGDNVEMSVELIHPIAMDPGLRFAIREGGRTVGAGVVAKVTA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_CORGL
Sequence: MATIANPRDIIIAPVVSEKSYGLMEQNVYTFFVSTDANKTQIKIAIEEIFGVKVASVNTVNRAGKRKRSRTGFGTRKATKRAYVTLREGSDSIDIFNGSVA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: EMC2_RAT
Sequence: MAKVTERYDVTWEEMRDKMRKWREENSRNSEQIMEVGEELINDYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKMKKDNIRYAGWAANQINRAYQFAGRSKKETKSSLKAVEDMLETLQITQS
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 2, Tetratricopeptide repeat protein 35, TPR repeat protein 35.
What is the protein family that this protein belongs to?
Belongs to the EMC2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=May also localize to the nuclear envelope.
Protein: GLND_ALIF1
Sequence: MKYLSPLSLSDTQLNITELKQQLTLFSQYQINAFHQHKAVSDLVLERSHYFDQLLSRLWQFFKFDDIANTSLIAVGGYGRSELHPLSDIDILILTENNTNDAFCQKVGELVTLLWDLKLEVGHSVRSIAECIEIGQNDLTVATNLQEARYISGNKELSHQLKLKIHSDSFWPSELFYQAKIDEQKKRHSRYHDTTYNLEPDIKSSPGGLRDIHTLSWIARRHFGATSLLEMSQAGFLTDAEYRELLECQEFLWRVRFALHIELKRYDNRLTFGHQASVAEHLGFIGEGNRGVERMMKEFYRTLRRVAELNSMLLKIFDQAILHQGEQDDAIIIDDDFQRRGRLIEARKPALFQARPDTILDMFLLMANDSTIDGVAPPTMRQLRTARRRLNRFLCEIPEAKEKFLQLTQHPNALNNAFSSMHKLGVLSAYLPQWSHIVGQMQFDLFHAYTVDEHSIRLLKHINKFSDTTNRDKHPICCEIFPKIMKKELLIIAAIFHDIAKGRGGDHSELGAVDAYDFCISHGLSKPEANLVSWLVKSHLLMSVTAQRRDIYDPDVITEFAKQVRDEERLDYLVCLTVADICATNPDLWNSWKRSLIADLYNATQRALRRGLENPPDLRDRIRHNQQMASAQLRSEGFTQWEVDALWRRFKADYFLRHTHKQIAWHASHLLRHQDKEKSLILISKNASRGGTEIFVYSKDQPHLFATVAAELDRRSITIYDAQVMSSKDGYALDTFMVLDQNDDPIDEERQQRLIDQLYDVKLNDQATHIKTRRPPRQLQHFNVKTRMEFLPTKTGKRTLMEFVALDTPGLLATVGATFAQLGINLHAAKITTIGERAEDLFILTSDVGGRLDDEKQAELELALVKNVARLSS
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: EIF3E_ASPNC
Sequence: MAANVPPSAETLLSGAAAHPPKTAEEIANQYDLLPKLIPYLDRHLVFPLLEFSSGSQEDDKEMIRAKYELLKHTNMTDYVANLWKEINDSDTIPDEFVKKREEVLAKLQHYQEQSAKITELLQDEDVVGNLRSDKVANLKFLEEEHGVTADMVNSLFDYGRFQYSCGSYGNAAELLYQFRVLSTDNDKVASATWGKLASEILTTSWDGAMEEVQKVKDSIETRLFNNPLGQLQNRSWLIHWSLFPFFNYDPARDVLTDLFFSPAYINTIQTSCPWILRYLAAAVITNRNRAHKNSNVYQKQLKDLIRVVRQEGYEYSDPITDFVKALYVDFDFEEAQKKLGEAEDVLRSDFFLVSAADAFVEAARHLISESYCKIHQRIDIKDLSTRLGLNQDEGEKWIVNLIRDTRVDAKIDYKEGTVIMNHPPQSVYQQVIEKTKGAFFRTQVLSAAVAK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y137_MYCPN
Sequence: MEKKPWEEDISIEEFKKSLNKDKITNLIIKRRWNKGKSTYHLSFNGDFEVVTKKPSTKYVTHKQLDQKLKEFKQDLMVELHDTFATKADLRDSEARINQKLEALVQVVLLHGEQINKLTQIVEKQGEQIRELQVEQKAQRQEFNARMDRLENLLVESIESTNKRFDSIEGRLDSMDSRLDSMENRLDSIEGRLDSVEGRLDSVEGRLDSMENRLDSMETRLDKIDPPK
What are the official names of this protein?
UPF0134 protein MPN_137.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: TRMD_VIBC3
Sequence: MWVGIVSLFPEMFRSVTDFGVTGQAVKKGLLSVEAWNPRDFAHDKRRTVDDKPYGGGPGMLMMVQPLRDAIHAAKQASPGKTKVIYLSPQGRKLDQQGVEELAQNQNLILICGRYEGVDERIIESEVDEEWSIGDFVMTGGELPAMTLIDSVSRFIPGVLGDFASAEEDSFANGLLDCPHYTRPEVLDGKEVPAVLKSGNHEDIRRWRLKQSLGRTWLRRPELLENLALTDEQEQLLTEYIKETRHQ
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YI61_XANEU
Sequence: MVSARPAFISGGPSTGGWRPTRQAAERTGGPEHSIEEVAGRGAPGHRSAEGWLRGKTLAPQRKREAIRRMLEHTPLSERRACRLAGLSRDAFRHAPVPTPATQALSARLVELAQTHRRFGYRRLHDLLRPEFPSVNHKKIYRLYEEAELKVRKRRKAKRPVGERQKLLASSMPNDTWSMDFVFDALANARRIKCLTVVDDFTRESVDIAVDHGISGAYVVRLLDQAACFRGYPRAVRTDNGPEFTSRAFIAWTQQHGIEHILIEPGAPTQNAYIESFNGKFRDECLNEHWFTSLAQARDVIADWRRHYNQIRPHSSCGRIPPAQFAANYRTQQANNAVPFNPGLYQ
What are the official names of this protein?
Insertion element IS476 uncharacterized 39.2 kDa protein.
Protein: HBL4_ORYSJ
Sequence: MAFASASNGAVRFTEEQEALVLKSWAIMKDDSANIGHRFFLKIFEVAPSARHLFSFLRNSDVPLEKNPNLKKHAMAVFVMTCEAAAQLRKTGRVTVRDTTIKRLGSTHFKNGVSDTHFEVARFALLETIKDGIPASMWSPEMKNAWGEAYEHLVAAIKEGMKPVALL
What is the function of this protein?
May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule.
What are the official names of this protein?
Non-symbiotic hemoglobin 4, ORYsa GLB1d, rHb4.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: MSHB_MYCTO
Sequence: MSETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVHVVTCTLGEEGEVIGDRWAQLTADHADQLGGYRIGELTAALRALGVSAPIYLGGAGRWRDSGMAGTDQRSQRRFVDADPRQTVGALVAIIRELRPHVVVTYDPNGGYGHPDHVHTHTVTTAAVAAAGVGSGTADHPGDPWTVPKFYWTVLGLSALISGARALVPDDLRPEWVLPRADEIAFGYSDDGIDAVVEADEQARAAKVAALAAHATQVVVGPTGRAAALSNNLALPILADEHYVLAGGSAGARDERGWETDLLAGLGFTASGT
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol (MSH) biosynthesis pathway.  Shows some amidase activity toward S-conjugates of mycothiol (By similarity).
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: KPTA_HYPBU
Sequence: MKPVYRCRVCSAYTEEPVHCGRPAEPLMTGEQRLRLSKLMTTLLRHLPHEAGLRLDPQGWVGIDELVRGIRERWRNRHLYQWVTRDHVIAVALLDPKGRFQLDLARGRIRAAYGHTVRVELGYRPLSMDELPDKLYHGTVAENLASILSEGLKPMRRLMVHMTTDYSSAVETGRRHGPNVVVLVIDPRCLAKHGIPVYRASDTIYLAPSVPPNCITGKIARNPQSARKTYLHA
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: CLIC6_RABIT
Sequence: MAETAEPEGGAPSPQGPPEGSALLEERPGEPDPAGPEASEGAAKAPSGEGAGAAAKAGATEEASGGRDGEGAGEQAPDAGTESGGETPDAKGAQIEAEGAPEGTKAPQLGEEGSGGKQVEESGPDCELRGEAAREAEGQAAAPAAPGAQEEAVPGDSVDAEGSIDAGGSVDAAGSVDAGGSIDAGGSMDAGGSVDAGGSIDTGGSVDAAGSVDAGGSIDTGRNVDAGGSIDAGGSVDAGGSMDAEGPAGGAHGAGGEPQDLGAGSPQPRSEAVEVAAAENEGHSPGESVEDAAAEEAAGTREPEGSEDAAGEDGDQGRPQEETEQQAERQEPGPETQSEEEERPPDRSPDGEAAASTRAAQPEAELSNHLAAEEGGQRGEGPANGRGEDGEASEEGDPGQEHDITLFVKAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGDVKTDVNKIEEFLEEKLAPPRYPKLATQHPESNSAGNDVFAKFSAFIKNTKKDANEIYEKSLLKALKKLDAYLNSPLPDEVDAYSTEDVAVSGRKFLDGDDLTLADCNLLPKLHIIKIVAKKYRDFEFPPEMTGIWRYLNNAYARDEFINTCPADQEIEHAYSDVAKRMK
What is the function of this protein?
May insert into membranes and form chloride ion channels.  May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport.
What are the official names of this protein?
Chloride intracellular channel protein 6, Parchorin.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Single- pass membrane protein. Note=Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane.
Protein: RECF_KINRD
Sequence: MHVAHLSLVDYRSYPTLELDLRPGTTTFVGLNGQGKTNLVEAIGYVATLGSHRVSGDAPLVRQGAERAVVRAQLERGGRRALVELEITPGKANRARLNGNPVRRTRDVLGVLRTVLFAPEDLALVKGDPGERRRYLDELLVTRWPRIAGVRADYDRILRQRTALLKSAGSAMRSGRADTHTLDVWDEHLATTGAELLSARLALLADLRSPTDSAYRAVSGGQGDLELGYRSSLPLLAEGVATTPGGEAPTRDALREALLASMLEQRKSELDRGVCLVGPHRDDLVLTLGGMPAKGYASHGESWSVALGLRLASYRLLLADDEVDDPGGPVLVLDDVFAELDAGRRERLSEVVADAEQVLVTAAVPEDVPAALRGEHTDRVHVTSGAAVRGD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAT_SALDC
Sequence: MNRLPSSASALACSAHALNLIEKRTLNHEEMKALNREVIDYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRRPFMPLLPGFRHVPFGNIDAMSMAFSEGKKTGDEIAAVILEPIQGEGGVILPPQGYLTEVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDTLLDGFRQLAREYPNLVHDARGKGMLIAIEFVDNETGYRFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIELCEQVLKSARNALAAMQVSVEEV
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: SET9_COCIM
Sequence: MAPTPPPKQKGKLTLAQLAAYDDIVTDALVDRAFFWTKIRKNRPKYFAVRGVVEDDVTSILLHDVIVAKDVIKAEKSLLNLSGLRKYVETLKSDKEKEWFRRHLRKYIAIYLPDCPFEVTTTNRYTITTHEAALSARKFIRTGDTIKHLSGTLVAITPEEEKTLDLTRRDFSIVMSSRKKTPSLFLGPARFSNHDCNPNARLVTKGSEGMEIVAIRDISIGEEITVSYGENYFGVDNCECLCHTCELSLSNGWSPGGPPEHDSRASTPETTEHQEKSSSGSEKRKSPPESPSHPSEDMPSKRPKFENILNLRLEISPPSSPDPIAEPLITVNGGLRALRSHFASLAGKSDLRHFQKPHSNFISASSSSDQTSCSLCPDDEAPTSTRSTSATSISDSNVQVKTEPTVEQQPRASSETAPKTISGDHGLHVQDIIRDNDESDLSDLSASWEINDREMTAVKREPVKKKKRKRKSSIIPTIEHEAPKARTPGDYTKTPKLLAQRYDRWVDCQTCNAWFVQGDAYLTRKECPRCERHSKLYGYRWPKTDREGRNDTEERVMDHRTIHRFLRTEDEARVQRRGRGVSHATSPTPDVSENKTETDASEFGDERRLTRSLRRARSSLRLAI
What is the function of this protein?
Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3.
What are the official names of this protein?
Histone-lysine N-methyltransferase SET9, SET domain protein 9.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: L_MABVP
Sequence: MQHPTQYPDARLSSPIILDQCDLLARSLGLYSHYSHNPKLRNCRIPHHIYRLRNSTALKTFLQNCSILTVPFHSIWDHILTSIQYDAINHVDDFKYLLPSELVKYANWDNEFLKAYLNKILGLDHVFPASARSQWEDFSPKENPYYWGMLLLVHLSQLARRIKGQRGSLRSNWKFIGTDLELFGIADFIIFKVPVKTIIRNAVSLQASKPGLRVWYRDQNLTPYLCDDEFIVSVASYECFIMIKDVFIERYNTWEICARAWLEDSDGADYLPLDVLGELYNQGDQIIAMYLEDGFKLIKHLEPLCVSCIQTHGIFTPGKYWFQSQRIESYYEELCSLNWKFKISGNKAECAQNFIKTIIQGKLTPQQYCELFSLQKHWGHPVLYIDVALDKVKKHAQSVKILKPKVMFETFCVFKFIVAKNHYHSQGSWYKTTMDLHLTPYLRQHIVSNSFPSQAEIYQHLWEWYFVEHEPLFSTKIISDLSIFIKDRATAVNQECWDSVFDRSVLGYNPPVRFQSKRVPEQFLGQADFSLNQILDFAEKLEYLAPSYRNFSFSLKEKELNIGRTFGKLPYRVRNVQTLAEALLADGLAKAFPSNMMVVTEREQKEALLHQASWHHNSASIGENAIVRGASFVTDLEKYNLAFRYEFTRHFIDYCNRCYGVKNLFDWMHFLIPLCYMHVSDFYSPPHCVTEDNRNNPPDCANAYHYHLGGIEGLQQKLWTCISCAQITLVELKTKLKLKSSVMGDNQCITTLSLFPIDAPDDYQENEAELNAARVAVELAITTGYDGIFLKPEETFVHSGFIYFGKKQYLNGVQLPQSLKTMARCGPLSDSIFDDLQGSLASIGTSFERGTSETRHIFPSRWIASFHSMLAINLLNQNHLGFPLGFSIDISCFKKPLTFSEKLIALITPQVLGGLSFLNPEKLFYRNISDPLTSGLFQLKNALEFLEKEELFYILIAKKPGLADASDFVMNPLGLNVPGSREIITFLRQTVRENITITSQNRIINSLFHIGSDLEDQRVCEWLLSSNPVMSRFAADIFSRTPSGKRLQVLGYLEGTRTLLASRTISLTTEGTMLMKLRELTRNRWKSWFSYIDALDDDLSESLEKFTCTVDIANFLRAYSWLDVLKGKRLIGATLPCLLEQFKVKWINLSEDLREQFNMSSESESTINLLPYDCKELRLGRSNDTELNYVSCALDRKVVQKHPSVNRLAWTIGNRAPYIGSRTEDKIGYPPLRVNCPSAALKEAIEMVSRLLWVTQGTADREKLLIPLLNSRVNLDYQTVLNFLPTHYSGNIVHRYNDQYGQHSFMANRMSNTSTRAIISTNTLGKYAGGGQAAVDSNIIFQNTINLGVAVLDIALSLAKLSSASNVTFRLMLNKCCTRHVPSEYLFFDKPLDVDLNKYMDNELVYDNDPLCSGIKGRLGRVSRSTLSLSLNVSDIGSYDFPTIAAWTLGETIVGSIFSDESSQSTDPISSGCTKTFVTHFLVYPVESIFYAFGANLIVESLSLSRIKSIKNLSDLTFLISSTIRNLSHRSLRILQSTFRHELVLTRLAHHIPLISLMLGGSAGEKSSSDAVRLFLTASYQNFINNFSCLMKKGQSSLPVWLYFPSEGQQLKPILKILQRLSDLLSPDKVQKHQILADTCCPIDSFWVYPSKSTRTNHYYASLNYWRDKANKVKNTPFSHLINCSFLELSSHTSSVSSNQQVTNSKYIVHPENIPEINARTKLIDYGSTALQGMDIKMPLSEQNLVGNCRPSKGIRFKDNPKTTKHDQGFVGKDSSPRPMSPEDNMQTPAYIHSSPPYQTLTKSPDVHEDFDASKVILNSEINNLNLTDCTLNTKSLTTPTGTEILGISPFRSSRYSSTSRERSRLSREQASYLYVDCSNIPSISLDPGFQNMSDQNQVQMLINTYKRDLHACFDSNQFCRFTGVVSSMHYKLYDLLPPGELRKAICLAEGEGSGARLLLKWKKTDYLFFNTLATDSQQEAEILSGRVIPRMLYNIDRLNALLESRRLILNNLTIQITDITSPLWLDSVIQYLPEDSDILTMDAETTKDETREQLYKTIVNIWTRTSPNIPKISIIKVFLLDYEGTLFLMRNAIQYYGQVQLKKPYSSNAKNSEWYLCCGKRRIQRLKIDFSDQVGIFLICKAMSRQRQAIPYWLKHIEKNYPASLHKFFLTLGFPSLESSFCHRYTIPFSEGKALFHKVQSYVRQGKQHLHSLMLDYENNSPLLDLRNHFICSLRGKITKYYNDILKLNLVIKAVEKGKNWSQLVETLPNMHSVCIVHVDHECFGCEKRLLLKLDFIRNTKIAEQKLLNRVIGYILFFPFGLFKSESLTA
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: CHEB2_BURP1
Sequence: MNIGIVNDLPLAVEALRRTIALRPEHRVLWVATDGAQALDFCVAQPPDLVLMDLVMPRIDGVSATRSIMERSPCAILIVTANVGANASYVYEAMGAGALDAVDTPTLEQGGSADPSQPLLAKIDQIGRLLATRMPLAAPAAAAPAPQGALPPLVAIGASAGGPTALTALLRRLPDDFPAALVIVQHVDQAFAIGMAQWLDGYSPLPVRIARQGSVPQAGEVLLAATNDHLHLTSRGVLAYTRRPEETPYRPSVDVFFHSVVDHWKGEAIGVLLTGMGRDGALGLKAMRTKGHYTIAQDEATSAVYGMPKAAAAIGAASAVLPLERIADQLISLVQRNRQRWR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRKC_BACSU
Sequence: MLIGKRISGRYQILRVIGGGGMANVYLAEDIILDREVAIKILRFDYANDNEFIRRFRREAQSASSLDHPNIVSIYDLGEEDDIYYIVMEYVEGMTLKEYITANGPLHPKEALNIMEQIVSAIAHAHQNQIVHRDIKPHNILIDHMGNIKVTDFGIATALSSTTITHTNSVLGSVHYLSPEQARGGLATKKSDIYALGIVLFELLTGRIPFDGESAVSIALKHLQAETPSAKRWNPSVPQSVENIILKATAKDPFHRYETAEDMEADIKTAFDADRLNEKRFTIQEDEEMTKAIPIIKDEELAKAAGEKEAEVTTAQENKTKKNGKRKKWPWVLLTICLVFITAGILAVTVFPSLFMPKDVKIPDVSGMEYEKAAGLLEKEGLQVDSEVLEISDEKIEEGLMVKTDPKADTTVKEGATVTLYKSTGKAKTEIGDVTGQTVDQAKKALKDQGFNHVTVNEVNDEKNAGTVIDQNPSAGTELVPSEDQVKLTVSIGPEDITLRDLKTYSKEAASGYLEDNGLKLVEKEAYSDDVPEGQVVKQKPAAGTAVKPGNEVEVTFSLGPEKKPAKTVKEKVKIPYEPENEGDELQVQIAVDDADHSISDTYEEFKIKEPTERTIELKIEPGQKGYYQVMVNNKVVSYKTIEYPKDE
What is the function of this protein?
Protein kinase that is responsible for triggering spore germination in response to muropeptides, signaling bacteria to exit dormancy.  PrkC is thus a germination receptor that binds peptidoglycan fragments containing m-Dpm (meso-diaminopimelate), which act as spore germinants.  Autophosphorylates and phosphorylates EF-G (elongation factor G, fusA); the latter modification is likely necessary for germination in response to peptidoglycan (PubMed:12399479).  Another group did not detect phosphorylation of EF-G (PubMed:19246764).  PrkC is a substrate in vitro of the cotranscribed phosphatase PrpC, which suggests that they form a functional couple in vivo.  Might also be involved in sporulation and biofilm formation.  Does not seem to be involved in stress response.
What are the official names of this protein?
Serine/threonine-protein kinase PrkC, Ser/Thr-protein kinase PrkC.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Spore membrane; Single-pass type II membrane protein. Note=Is associated with the inner membrane of the spore.
Protein: ZMAT4_HUMAN
Sequence: MKSSDIDQDLFTDSYCKVCSAQLISESQRVAHYESRKHASKVRLYYMLHPRDGGCPAKRLRSENGSDADMVDKNKCCTLCNMSFTSAVVADSHYQGKIHAKRLKLLLGEKTPLKTTATPLSPLKPPRMDTAPVVASPYQRRDSDRYCGLCAAWFNNPLMAQQHYDGKKHKKNAARVALLEQLGTTLDMGELRGLRRNYRCTICSVSLNSIEQYHAHLKGSKHQTNLKNK
What are the official names of this protein?
Zinc finger matrin-type protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2601_AERPE
Sequence: MVGMGDRLFNMVFTRRPPQSMSRCISDPGYRAAARFSYEEASAQYKVYVERLHSAGITVKELGPLEDYPDSVFIQDTAVIGGGSRVAVLARFGAPSRRGEEGHVVSILSSMGLEIHPVKPPGTLEGGDVLVTGEGVVFAGLSSRTNREGVETLKTAFPNVNVETLNAKGLHLLSHLGYLGKATLISAEGLYDKSIFKRHGFDLIEIPWEERDAANLLYLGEGRVLLPAGYNQTRDLLEQHGFRIVEAEIRQFMACMGGVTCLSLPIYNIL
What are the official names of this protein?
Uncharacterized protein APE_2601.1.
What is the protein family that this protein belongs to?
Belongs to the DDAH family.
Protein: EFG_BEII9
Sequence: MPRSHPIEDYRNFGIMAHIDAGKTTTTERILYYSGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWNGRRLNIIDTPGHVDFTIEVERSLRVLDGAVCVLDGNQGVEPQTETVWRQADKYNVPRIVFVNKMDKIGADFYRCVEDIKTKVGGRPVCIQLPIGSEADFKGIIDLVRMKAVVWEDEALGAKYHDEEIPDDLKEKAIHYRNLLVEAAVELDDDAMTAYLEGVEPDEALLKLLIRKAVRQITFIPVLCGSAFKNKGVQPLLDAVVDYLPTPIDREAIKGVDVNTGEETVRLPSDSEPFSMLAFKIMDDPFVGSITFARVYSGKIESGTSVVNSTKDKKERIGRMLLMHANNREDIKEAYAGDIVALAGLKETRTGDTLCDVNKPVILERMEFPEPVIEIAIEPKSKADQEKLGIALSKLAAEDPSFRVSTDQESGQTILKGMGELHLDIKVDILKRTYKVDANIGAPQVAYREKLMRRVEIDETHKKQTGGTGQFARVKMIFEPNEAAAGNAFESNIVGGAVPKEYIPGVEKGLYSVLNSGVLAGFPVVDVKATLIDGAFHEVDSSVLAFEICSRAATRRALKEGGSVLLEPIMKVEVTTPEEYTGSVMGDLLGRRGQVQGQDMRGNAVVINAMVPLANMFGYVNQLRSFSQGRANYSMQFDHYEQVPANEAAKVQAKYA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN121_HUMAN
Sequence: MAAVVEVEVGGGAAGERELDEVDMSDLSPEEQWRVEHARMHAKHRGHEAMHAEMVLILIATLVVAQLLLVQWKQRHPRSYNMVTLFQMWVVPLYFTVKLHWWRFLVIWILFSAVTAFVTFRATRKPLVQTTPRLVYKWFLLIYKISYATGIVGYMAVMFTLFGLNLLFKIKPEDAMDFGISLLFYGLYYGVLERDFAEMCADYMASTIGFYSESGMPTKHLSDSVCAVCGQQIFVDVSEEGIIENTYRLSCNHVFHEFCIRGWCIVGKKQTCPYCKEKVDLKRMFSNPWERPHVMYGQLLDWLRYLVAWQPVIIGVVQGINYILGLE
What is the function of this protein?
E3 ubiquitin ligase which accepts ubiquitin and transfers it to substrates thereby promoting their degradation by the endoplasmic reticulum-associated degradation (ERAD) pathway which is a pathway involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (By similarity).  May regulate the unfolded protein response to reduce endoplasmic reticulum stress (By similarity).
What are the official names of this protein?
E3 ubiquitin ligase RNF121, RING finger protein 121.
What is the protein family that this protein belongs to?
Belongs to the RNF121 family.