PharMolix/UniProtQA huggingface dataset:
Protein: RSMF_ECOUT
Sequence: MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDSEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNKGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRLGGTLVYSTCTLNREENEAVCLWLKETYHDAVEFLPLGDLFPGANKALTEDGFLHVFPQIYDCEGFFVARLRKTQAIPVLPAPKYKVGNFPFSPVKDREAGQIRQAAASVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIALASPDNVNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTGNA
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNS1D_RAT
Sequence: MGLEKSFILFSLLVLVLGWVQPSLGRKPSVQDFKRQHMDPDSPPNSRPTYCNQMMKRRGMTKGSCKRVNTFLHESWATVKAICSQRQMTCKTSSRNNCHKSSSTLHITDCRLKGSSKYPNCDYTTTNSQKHIIIACEGNPLVPVHFDASV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic delta-type, RNase 1 delta.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNAS1_GALMU
Sequence: AESSAMKFQRQHMDSDGHPDTNTNYCNEMMVRRSMTQGRCKPVNTFVHEPLEAVQAVCSQKNVPCKNGQTNCYQSHSSMRITDCRVTSSSKYPNCSYRMTQAQKSIIVACEGTPSVPVHFDATV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPG_STAAN
Sequence: MASLKEIDTRIKSTKKMKQITKAMNMVSSSKLRRAEKNTKQFTPYMDKMQDAITAVAGASSNTNHPMLRPRKITRSGYLVITSDKGLAGAYSANVLKKLITDIEAKHQDSSEYSIVVLGQQGVDFLKNRGYDIEYSQVDVPDQPSFKSVQALANHAIDLYSEEEIDELNIYYSHYVSVLENKPTSRQVLPLSQEDSSKGHGHLSSYEFEPDKESILSVILPQYVESLIYGTILDAKASEHATRMTAMKNATDNATELIDDLSLEYNRARQAEITQQITEIVGGSAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NUOB_RICRO
Sequence: MKNNFYQEDELLSNELSNRGFLLTKVDDVIGWARANSLWPMTFGLACCAVEMMQAAASRYDMDRFGMLFRPSPRQSDLMIVAGTLTNKMAPALRKVYDQMAEPKWVLSMGSCANGGGYYHFSYSVVRGCDRIVPVDVYVPGCPPTAEALIYGLMQLQKKIKRTTGFKYDARQTH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL11_BLOFL
Sequence: MIVKKKVQSCIKLQIEARSATPSPPIGPALGQQGINIMKFCKDFNTRTADFEMGLILPVVITVYVDRSFSFVIKTPTAVFLLKKAAGIKSGSEKPKCVSVGKVLISQIYEIAKIKLIDMTSLNLESASKSIMGTARSIGLEVEDNL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PHNW1_POLSJ
Sequence: MTTDAILLTPGPLTTSSRTKQSMLRDWGSWDTDFNAITARLRQGLLRIVHGEGTHECVPLQGSGTFSVEAAIGTLVPPGEKGGHVLVPVNGAYCQRIAKICKVLGRKLTTFEYAEDAQIRPEDIDRLLAKDPSITHVALVHCETSTGILNPLHEIALVVQRHGKGLIVDAMSSFGALEIDARKTPFDAVVAASGKCLEGVPGMGFVLARRAALERCEGNCHSLAMDLYDQWVYMNKTTQWRFTPPTHVVAALDAALTQYFEQGGLAARGGAYAKNCRELISGLAGLGLRSFLPAAIQAPIIVTFHAPASPAYEFKAFYNAVRQRGYILYPGKLTAVETFRVGCMGQLGARGMAGAVEAVRDALQEMGLELANAE
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase 1, 2-aminoethylphosphonate aminotransferase 1, AEP transaminase 1, AEPT 1.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: CPE1A_XENLA
Sequence: MAFPLKDDLGRAKDCWGCPSDTPALSTCSNADIFRRINAMLDNSLDFTGVCTTPNTKGKCEHLQDYQDTEGPAASRMLFSTSHEPLPRGLPDTNDLCLGLQSLSLTGWDRPWSTQDSEAGGHSSTPTAAQSVFSMLNSPMGKPSPLGFLTFDPIGSDLMEKYPTPLLRSSRLDSRSILDSRSSSPSDSDTSGFSSGSDHLSDLISSLRISPPLPFLPLGGGVSRDPLKLGIGSRLDQDHAALAAATVSPLGITKGWPSTSVWPSWDLLDSAEDPFSIEREARLHRQAAAVNEATCTWSGQLPPRNYKNPVYSCKVFLGGVPWDITETGLINTFRVFGALSVEWPGKDGKHPRCPPKGNMPKGYVYLVFESEKSVRALLQACSQDLLSQDGLSEHYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSKTVFVGALHGMLNAEALASIMNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVSAAFVEIKTAKFTKKVQIDPYLEDSVCQVCNAQPGPFFCRDQVCFKYFCRSCWHWQHSMEILRHHRPLMRNQKSRDSS
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation and early development.  Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR.  In the absence of phosphorylation and in association with tacc3/maskin, also acts as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation.  Requires zinc for RNA binding.  Involved in the cell cycle progression from S phase into M phase.
What are the official names of this protein?
Cytoplasmic polyadenylation element-binding protein 1-A, CPE-BP1-A, CPE-binding protein 1-A, CPEB-1-A, 58 kDa CPE-binding protein.
What is the protein family that this protein belongs to?
Belongs to the RRM CPEB family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Membrane. Note=During mitosis localizes with tacc3/maskin and CPE- containing mRNAs to both spindle poles. Membrane-associated. Colocalizes with members of the polyadenylation and translation complex factors (cpsf, aplp1, tacc3/maskin, aurka, etc.), including CPE- containing RNAs.
Protein: MIAA_BACC1
Sequence: MGEVQREKVAVIIGPTAVGKTKLSIDLAKALNGEIISGDSMQIYRTMDIGTAKVTKEEMDGIPHYMVDIKNPEESFSVAEFQERVRKHIREITERGKLPIIVGGTGLYIQSVLFDYQFTDDAGDVIYREHMEKLALERGVEYVHKKLQEVDPESAERIHANNVRRVIRALEIFHTTGEKMSDQLEKQENELLYDVSLIGLTMDREMLYDRINLRVDIMMDQGLLEEVEGLYNRGIRDCQSIQAIGYKEIYDYFEDRVSLEEAVSQLKTNSRRYAKRQLTWFRNKMDVTWFDVTDGEKTSEILRYIEGKLQLKSNNSK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: HCP_METJA
Sequence: MFCFQCQEAAKNEGCTIKGVCGKDDVVANLQDLLIYTIKGLCYVCDKGNYLDDEVMDYIPKALFVTITNVNFDDKDVINWIKKGVALREKIIEKNNLNKEELPYCATWAYETDEDLINLANTKEVSVLAEDNEDIRSLKELITYGIKGIGAYLSHAMHLGYNNEDIHKFIIKAFTKIVDSKDADELFNLAMETGKYAVETLALLDKANTETYGHPEITEVNLGVRDRPGILISGHDLKDLEQLLEQSKDAGVDIYTHCEMLPAHYYPFFKKYEHFVGNYGGSWPFQREEFEKFNGPIVMTTNCLVPPKDSYKDRVYVTNEVGYPGLKRIPVKEDGTKDFSEVIEHAKKCKPPTPLENGKIVGGFAHNQVLALADKVIEAVKSGKIRKFVVMAGCDGRHKTREYYTEFAKKLPKDTVILTCGCAKYRFIKLDLGDIDGIPRVLDAGQCNDSYSLVKIALALKDAFGLNDVNELPIAYNISWYEQKAVTVLLALLYLGVKNIVLGPTLPAFLSPNVTKVLVEKFGISTISTVDEDIKRLVG
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_MACFA
Sequence: MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNAEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLFGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEARAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGSNFGPIFMTIPAFFAKSASIYNPVIYIMMNKQFRNCMLTTICCGKNPLGDDEASATVSKTETSQVAPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Required for photoreceptor cell viability after birth (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: RPOC1_GUITH
Sequence: MSKLEQYFDYVKINLASPQRIKKWGERRLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPVKDWECHCGKYKRVRYKGIVCERCGVEVAESKVRRHRMGYIELAAPVTHVWYLKSLPSYISILLDIPLKDVEQVVYFNSYVVTKPGNCTNLRYKQLLSEDEWIAIEDQLYQEDSELTGVEVGIGAEAIQKLLRDIDLEVEAESLREEILVVKGIKKDKSIKRLRVIDNFIATRSDPTWMILTVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVLNRNNRLIRLQEILAPEIIIRNEKRMLQESVDALIDNGRRGRTVMGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPQLELNQCGLPREMALELFQPFVIHKLIQQGLVNNIKAAKRLIQKNELIVWNVLEEVIQGHPILLNRAPTLHRLGIQAFEPILVEGRAIKLHPLVCPAFNADFDGDQMAVHIPLSLEAQAEARMLMLAPYNFLSPATGDPIIMPSQDMVLGCYYLTAENPSQQVNRSLYFSNFDDVLLAYETKLIKLHSYVWVRFNGNVDDDDEKIEEKKLDGNKKLHIYPSRIKKLDQDNNLMVQYILTTPGRILLNNVLFDSLQLQF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: METK_BURO0
Sequence: MANDYLFTSESVSEGHPDKVADQISDAILDAILEQDKYSRVAAETLCNTGLVVLAGEITTTANIDYIQIARDTIKRIGYDNTDYGIDYKGCAVLVAYDKQSPDIAQGVDRAHDDNLDQGAGDQGLMFGYACDETPELMPLPIYLSHRLVERQASLRRDGRLQWLRPDAKSQVTVRYVDGKPDSIDTVVLSTQHAPDIELPALREAVIEEIIKPTLPAELIKGDIKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALIQVSYAIGVAEPTSVMVNTFGTGRVSDAVITKLVREHFDLRPKGIIKMLDLLRPIYEKTAAYGHFGREEPEFSWEATDKALALAEAAGVEPTARVA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
Protein: F16P2_ARATH
Sequence: MDHAADAHRTDLMTITRFVLNEQSKYPESRGDFTILLSHIVLGCKFVCSAVNKAGLAKLIGLAGETNIQGEEQKKLDVLSNDVFVNALVSSGRTSVLVSEEDEEATFVEPSKRGKYCVVFDPLDGSSNIDCGVSIGTIFGIYTLDHTDEPTTADVLKPGNEMVAAGYCMYGSSCMLVLSTGTGVHGFTLDPSLGEFILTHPDIKIPNKGNIYSVNEGNAQNWDGPTTKYVEKCKFPKDGSPAKSLRYVGSMVADVHRTLLYGGIFLYPADKKSPNGKLRVLYEVFPMSFLMEQAGGQAFTGKKRALDLVPEKIHERSPIFLGSYDDVEEIKALYAEEEKKN
What is the function of this protein?
Catalyzes the first irreversible reaction from fructose-1,6-bisphosphate to fructose-6-phosphate and inorganic phosphate and plays an important regulatory role in sucrose biosynthesis and metabolism (Probable).  Its activity is essential to regulate starch levels (PubMed:25743161).  Functions in fructose-mediated signaling independently of its catalytic activity in sugar metabolism.  May act downstream of ABA2/GIN1, which is involved in abscisic acid (ABA) synthesis to regulate autotrophic transition and modulate early seedling establishment after seed germination (PubMed:21253566).
What are the official names of this protein?
Fructose-1,6-bisphosphatase, cytosolic, FBPase, D-fructose-1,6-bisphosphate 1-phosphohydrolase, Protein FRUCTOSE INSENSITIVE 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CBID_PROMT
Sequence: MNQFTLPVWVVAAAKSATNILIGNKFRDKERIDLPNNEKSISVPISSSALLDNGKRSLAVSHCQSGLPLDITRGVEIWAYIQLSKGGFQSKGKVRNGFPDWLDFHAGYGVGKFQSSGQPCISQFARDLLCINLYPLLPKGSSIKVEIILPEGKDRASKTSNEAFGVVDGLSLIGTQAEVQISASPDQLKNTKELLHHKCSEAKFDGCLTFVIGENGMDLAMKYGLPANQIIKTGNWLGPLLVAAAENGVKKLLLFGYHGKLIKLSGGVFHTHHHLADGRIEILTSIAFREGISFDLIELISKSTSVENALLTLEVSNPEAVSLIWSRMAKEIEIKSRSYVNRYLSSSMEIGSVLFDRKRQMRWAGLEGLKQINSLGLILKR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: THOP1_PIG
Sequence: MKPPAACAGDALDVAAPCSAVNYLRWDLSAQQIGELTTELIEQTKRVYDRVGTQELQDVSYENTLKALADVEVSYTVQRNILDFPQHVSPCKDIRTASTEADKKLSEFDVEMSMRQDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPKETQEKIKSIKKKLSLLCIDFNKNLNEDTTFLPVTREELGGLPEDFLNSLEKTEDEKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILRELVRLRAQKSSLLGFSTHADYVLEMNMAKTSQVVATFLDELAQKLKPLGEQERAVILELKKAECTKRGLDFDGRINAWDMRYYMNQVEETRYRVDQNLLKEYFPMQVVTRGLLGIYQELLGLTFHLEEGAAVWHEDVMLYSVRDAASGKVIGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTPDAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEAEPLLRMSQHYRTGSAIPQELLEKLIKSRQANTGLFNLRQIVLAKVDQALHTQTAADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSADMFHTRFKQEGILSGKVGMDYRSCILRPGGSEDASVMLKLFLGRDPKQDAFLLSKGLQVEGCEPPAS
What is the function of this protein?
Involved in the metabolism of neuropeptides under 20 amino acid residues long (By similarity).  Involved in cytoplasmic peptide degradation.  Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments (By similarity).  Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1 (By similarity).
What are the official names of this protein?
Thimet oligopeptidase, Endopeptidase 24.15.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK32_THAPS
Sequence: MAVPKKRTSKAKKNSRKANWKRKAAKSAQKSLSLAKSILRGKTTSFVYRLYVDE
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SWS2_SCHPO
Sequence: MVYILGVAVNDDKPVRFALLSFYGIGHAKAEEICAKLSFHNTLRVRELTNVQLTTLSQLLSGMTIEGDLRRQRNADISRLVNIRCYRGMRHVNGLPVNGQNTRTNAKTAKKLNKVPRRGYMTLSPASTRPITWSFCLPRMVSVFQKLKHIH
What are the official names of this protein?
37S ribosomal protein subunit sws2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSRP_JANMA
Sequence: MSQPVERSPASTRTVFFVSDGTGITAETFGHSVLTQFELRFKQVRLPFIDTPDKAYDALRKINETFAADGQRPIIFSTLVKADLSSIVRQSQGMHMDLIQTFVEPLEQELGVKSTHTIGRSHTSTDSEEYKNRIEAINFSLAHDDGQSHKNLSAADVILVGVSRSGKTPTSLFLAMQYGIKAANYPLIPDDFEREKLPGGLQAYKHKIFGLSIAADRLAEIRNERLPGSKYAALENCRYEVNEAERMMRREGIRWMSSTTKSIEEIAATILQEIKLDPPIKD
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: RAD17_CHLAE
Sequence: MNQVTDWVDPSFDDFLECRDISTITATSLGVNNSSHRRKNGPSTLESSKFPVRKRGNLSSLEQIYSLENSKESLSENEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTIKVLSKEHGIQVQEWINPVLPDFQKDDFREIFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFVISDSLSGDNNQRLLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSGDIRSAINSLQFSSSKGENNLWPRKKGMSLKSDAVLSKSKRRKKPDRVFENQEVQAIGGKDVSLFLFRALGKILYCKRASLTELDSPRLPSHLSEYERDTLLVEPEEVVEMSHMPGDLFNLYLHQNYIDFFMDIDDIVRASEFLSFADILSGDWNTCSLLREYSTSIATRGVIHSNKARGYAHCQGGGSSFRPLHKPQWFLIYKKYRENCLAAKALFPDFCLPALCLQTQLLPYLALLTIPMRNQAQISFIQDIGRLPLKRHFGRLKMEALTDREHGMIDPDSGDEAQLNGRHSTEESLGEPTQASAPETWSLPLSQNSASELPASQPQPFSAQGDMEENIIIEDYESDGT
What is the function of this protein?
Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage.  Has a weak ATPase activity required for binding to chromatin.  Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation.  May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination (By similarity).
What are the official names of this protein?
Cell cycle checkpoint protein RAD17.
What is the protein family that this protein belongs to?
Belongs to the rad17/RAD24 family.
What are the subcellular locations of this protein?
Nucleus. Note=Phosphorylated form redistributes to discrete nuclear foci upon DNA damage.
Protein: PYRC_PSESM
Sequence: MSDRLTLLRPDDWHIHLRDGAVLPHTVADVARTFGRAIIMPNLVPPVRNAQQADAYRQRILAARPAGSRFEPLMVLYLTDQTTPEDIRTAKASGFVHAAKLYPAGATTNSDSGVTSIDKIFPALEAMAEVGMLLLVHGEVTRGEIDVFDREKVFIDEHLRRVVERFPTLKVVFEHITTGDAVQFVNEASANVAATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGSGKFFLGTDSAPHAQHAKENACGCAGCYTAYAAIELYAEAFEQRNALDKLEGFASLHGPAFYGLPANQDTITLVRDEWTAPTSLPFGELTVIPLRAGETLRWRLEEHA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: TRMD_HALHL
Sequence: MTGTPNSRRIDVITVFPEMVEQVARFGVVGRAAERGLIELSAWNPRDYAEDRHATVDDRPYGGGPGMVMKVAPLHRAIQAARAADPRPARVIHLSPQGARLDQDRVARLAACERVIYLCGRYEGIDERLLEAEVDEELSIGDYVLSGGELAAMVAIDAATRLVPGALGHEDSAAEDSFATGLLDHPHYTRPEVYERRGVPEVLRSGDHGAVDTWRLKQALGRTWLRRPDLLAGRELDERQRRLLDEFIAEHRAEARAGNDHDET
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF62_ASFB7
Sequence: MNWGSISSGTPGLFVESIRNTPSVVKINVIFLKVISNTAVSVFWRDRRIRFESDWLNSYFQK
What are the official names of this protein?
Uncharacterized protein C62L, pC62L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C62L family.
Protein: NUOH_LEPBA
Sequence: MDWALILAWGIKILSLFFVILTGVAYYTLAERKFAGFIQDRPGPNRAGPFGIFQPLADGIKFIAKEEIFPKNVSKGMYLLAPTISMTCAIMAWAVIPFGGTLPAPEWLTTLTGVATIDLQIANPDSGVLYMLAISSLSVYGIMIAGWSSNNKYSLLGGVRSTAQMISYELPMGLSIVAIVIMTGSLKLTDISDSQKDMWNILSPPGFVAFFIYVTAMFAETNRLPFDLAEAESELVVGFHTEYGAFKFALFFLAEYMNMITMSCLTTLLFFGGYNVPFQLGAGSEYQAFIGLGFFILKVLFFAFLFIWVRWTLPRFRYDQLMKLGWKKMIPWGLFVVMFASIYTVYWKEGWMKLFI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHS_AFIC5
Sequence: MGDLLSDEARRAALVELPGWREADGGKAFTRTFTFRNFNEAFGFMTRAALVAEKNDHHPDWRNVYKTVEVNLSTHDAGGITARDVALAKKMNEIAARFGI
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: MKT1_YEAST
Sequence: MAIKSLESFLFERGLVGSYAIEALNNCTLDIDVNHYVSRLLTNKREQYLDAIGGFPTSLKMYLESDLKIFKDFNITPIFVFNGGLTYNQLEASGHFTAASASASISSTTTSSSGTNATTRSNTESVLLQRSRGWTQWNNLISSNQNSYIDQPIQPQEPFRHNTTIDSKAYQNDLIAYFIEHGYMYQVAPYSSWFQLAYLLNSAYIDAIYGPTDCLMLDCVDRFILGMEFPNKEFRFIDRSRVMKDLGCTHEEFIDIAMAVGNDLQPTTLPPLQIYPVPQLFDIALEMVLNTGTNFYAYQLSTTLQNDSKENIQNYQRGISALRYMPVLKDTGKVELFVQEIVVSEEDSEKNNKDGKKSNLSSPSSASSSASPATTVTKNASEKLTYEKSSTKEVRKPRDIPNDVHDFIGQMLPHEYYFYRSIGLVTGKLFDAIVTGVYPEEPPLGGGSSTSYKKLVSKSVEIFKNKEINLLTQPINRYYQIKQIKQVKWYAANEPTTLTNRMSPSMFETINHLIVKTETSDEKEFSISEFITTINGSSNMAKDFISEKVIFPNSVPIESKLNSPFNLLSTNFLRLLVLLEFFTFDFKEKLLEPTRWGEVFLKLNELNIDSKYHESVIIFLVFLKCDVLKLDEEVQPPAPSALSQATLRSYPEESLYVLLITRVLTLFQVDQKPSNYHGPIDKKTLIFRDHLSFIKENLNELFEAVLISSLTSGEFNRLSLDNFGWARKIVRYLPFKLDSPNTIMAMMWEFFLQKYLHNGNAKNDALSLVATEFNTYKSTPNLDEQFVESHRFLLEISKVMQELNAAKLIDENVFKLFTKAVEFTTTALSS
What is the function of this protein?
Involved in 3'-UTR mediated RNA regulation (PubMed:15082763).  Binds to RNA-binding and RNA regulatory proteins (PubMed:15082763).  Complexes with PAB1-binding protein to promote mRNA interactions with poly(A)-binding protein (PubMed:15082763).  Promotes mating-type switching in mother cells by positively regulating HO expression (PubMed:15082763).
What are the official names of this protein?
Post-transcriptional regulator MKT1, Inactive endonuclease MKT1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Localizes to polysomes in a PBP1-dependent manner.