PharMolix/UniProtQA huggingface dataset:
Protein: PANB_GEOTN
Sequence: MKTKADFFRMKQADEPIVMVTAYDFPSAKLVEQAGVDMILVGDSLGMVVLGYDSTIPVTVDDMIHHTKAVRRGAPNTFIVTDMPFMSYHASKEEALQNARRIMQQSGANAVKVEGADEVVETIAALTKAGVPVVAHLGLTPQSVGVLGGYKVQGKDAESAKKLLNDAKQCEQAGAIALVLECVPKQLGAAVARELTIPVIGIGAGAEVDGQVLVYHDLLGYGVNRVPKFVKQYAAIQETIVEALANYIADVKLRQFPEPAHTFTMKEEEWVALYGGKQS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRE_YERPN
Sequence: MEHYISLLVRAVFVENMALAFFLGMCTFLAVSKKVSTAFGLGIAVTVVLGISVPANNLVYNLVLRDGALVEGVDLSFLNFITFIGVIAAIVQVLEMILDRYFPALYNALGIFLPLITVNCAIFGGVSFMAQRDYNFPESIVYGFGSGMGWMLAIVALAGIREKMKYANVPAGLQGLGITFISTGLMALGFMSFAGVNL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EHF_MOUSE
Sequence: MILEGSGVMNLNPANNLLHQQPAWTDSYPTCNVSSGFFGSQWHEIHPQYWTKYQVWEWLQHLLDTNQLDASCIPFQEFDISGEHLCSMSLQEFTRAAGSAGQLLYSNLQHLKWNGQCSSDLFQSAHNVIVKTEQTDPSIMNTWKEENYLYDPSYGSTVDLLDSKTFCRAQISMTTSSHLPVAESPDMKKEQDHPVKSHTKKHNPRGTHLWEFIRDILLSPDKNPGLIKWEDRSEGIFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN
What is the function of this protein?
Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation.  May act as a repressor for a specific subset of ETS/AP-1-responsive genes, and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades.  Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.  Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter (By similarity).
What are the official names of this protein?
ETS homologous factor, ETS domain-containing transcription factor.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIP1_CAEEL
Sequence: MPKNLRFSVFLLFLLCINSVFGEFGPEDAQYNETEARMLLSLSAAAYSLDVTPCIGRTFSPAENQTLLSTFSVRCDFVGNPCAGYIVVSDVLQQITVVFRGTKTSSQLLLEGWTTLKPSSDFYGMGLVNTYFRSGHEKTWQYVQDALSISQYRNYDVYVTGHSLGGALAGLCAPRIVHDGLRQSQKIKVVTFGEPRVGNIEFSRAYDQLVPYSFRVVHSGDVVPHLPGCVKDLSYTPPAGSDGSMPCDPVSTNGGYHHAIEIWYPGNMTQGDPFMVCTGLPRDEDFGCSDSLKVNLGDTNQGVWDHRNYFGVEVPDFGKGGCDPSMTFKGPPTKTGVLSLVGSVFGRKRRSIR
What is the function of this protein?
Probable lipase.
What are the official names of this protein?
Lipase ZK262.3.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTH_PECCP
Sequence: MNSPTVHTTAPPHEQALLERAQSLAGYNLAELADIARLPLPANLKRDKGWIGVLLERFLGASAGSKPEQDFPDIGVELKTIPIDEQGKPLETTFVCVAPLTGNSGVTWESSHVRHKLARVLWIPVEGSRHIPLGERRIGTPLIWSPSEEEEEQLRCDWEELMDLIVLGQVESITARHGEVLQLRPKAANSRALTEAIGEFGQPILTLPRGFYLKKTFTAPLLARHFMQLSN
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_HERAR
Sequence: MNGESGDAITSRRIVLGVQYDGAPWQGWQTQLNGLTVQDKLEFALYKFTQQTITTACAGRTDAGVHALEQVVHFDTTLERDMQSWVRGVNTFLPSSIAVRWASEVAHDPAENFHARFSARSRTYHYMLYNNPVRSPLLEGKAGWVFRALDIAKMQEAAAHLLGQHDFSAFRSVQCQAKSPVKTMHAIKIERRGDLIMFTVHANAFLHHMVRNIVGSLIYVGNGTQAPSWLKEVLAGQERKFAAPTFMPDGLYLAKIDYDPKWQLPQTEIQNFLWS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ARLY_ERWT9
Sequence: MALWGGRFTQPADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVNVLTAAEQQQLESALTALLDEVRADPQQILASDAEDIHSWVEGKLIDKVGALGKKLHTGRSRNDQVATDLKLWCKEQVSELLNATRQFQQALVATAEAHQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDTLKRLDVSPLGCGALAGTAYDIDREQLAGWLGFASATRNSLDTVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNTGEAGFVELSDKVTSGSSLMPQKKNPDALELIRGKVGRVQGALTAMSMTLKGLPLAYNKDMQEDKEGLFDALDTWADCLHMAALVLDGIQVKRPRCQEAAEQGYANSTELADYLVAKGVPFREAHHIVGETVVEAIKQGVALEALKLSDLQKFSHVIGDDVYPILSLQSCLDKRNAKGGVSLHQISQAITEAKQRLA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIA_PELPD
Sequence: MSINGFLIAAPQSGSGKTTISLAIMAALRRRGLVVAPFKCGPDFIDPGYHRMASGRASINLDGWMCPESFVAETFRLHAEAADVAVIEAVMGLFDGLGASPLQGSSAQIAAICGAPVVLVVNARGMAASAAALVKGFAEFDPDVRLAGVIFNNVGSAGHAELLARVMASALPEIALLGCIPRDEALAIPSRHLGLVTAEDNPLPPEYLDRLADLAEKHLDLAGLAGLRITPRSVGASLSRTNGGGMLPVRIAVARDAAFCFVYQDNLRLLREAGGELLFFSPLADGALPEGISGIYLPGGYPELYAERLAVNVPMLDAIRGAARDGMPLYAECGGFIYLTRGMEDSQGAPLADFAGIFPVRARMLPKRKALGYRQVECLSVSILGPAGETARGHEFHYSEICEMPVDVTRTYSVTRQGAFLGQEGYCLSNCLASYVHLHFGSNPCLAPSLVAACRKFAATRRS
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: CDO1_RAT
Sequence: MERTELLKPRTLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKFGIRTPFTTSGSLENN
What is the function of this protein?
Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.
What are the official names of this protein?
Cysteine dioxygenase type 1, Cysteine dioxygenase type I, CDO, CDO-I.
What is the protein family that this protein belongs to?
Belongs to the cysteine dioxygenase family.
Protein: RUVB_BACC7
Sequence: MDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLSRLEYYTVDQLSEIVERTAEVFEVEIDSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTVTMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFRGGPVGLETVSATIGEESHTIEDVYEPYLLQIGFLQRTPRGRIVTPLAYEHFGMEMPKV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: URE2_STAAC
Sequence: MIPGEIITKSTEVEINNHHPETVIEVENTGDRPIQVGSHFHFYEANAALDFEREMAYGKHLDIPAGAAVRFEPGDKKEVQLVEYAGKRKIFGFRGMVNGPIDESRVYRPTDENDEYAGVFGDNGAENVNKKGGKRS
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_SORC5
Sequence: MTNATSAPPARADRAPASKALFDRAAAVLPGGVNSPVRAFRAVGGDPLFIARAQGARLFDADGAEYIDYVGSWGPAILGHAHPAVIEAVREAALGGLSFGAPTELEVRFAEKIRELYPSIDMLRCVSSGTEATMSAIRVARGFTRRDAIIKFEGCYHGHADHLLVKAGSGLATFGAPDSAGVPESIARTTLSLPYNDPAALEAAFAARGGDIAAVILEPVVGNMGCVPPEPGFLALVIDLCRKHGALSIFDEVMTGCRLARGGAQERFGLRPDLTTLGKIVGGGMPLAAYGGRADVMRVVSPLGPVYQAGTLSGNPLAVTAGLATLDRLTPALYERLEELGASLEEGLRAAAEGAGAAACVQRVGSMITLFFTKGPVRSWADAATSDTKRFSAFHAAMLARGIYWPPSQYEAAFLSGAHSEEDIERTIAACREALAA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTU1_AEDAE
Sequence: MPILCTTGCSRKAFLKRPKTGDTLCRECFFLAFETEIHNTIEQNKLFRRGDVVAIAASGGKDSTVLAHVLKVLNERYDYGLKLVLLSIDEGITGYRDDSLETVKRNRDDYGMELKILSYDELYGWTMDKIVSKIGRSNNCTFCGVFRRQALDRGARLMEVDCVATGHNADDIAETVLMNILRGDTARLRRCCDIKTGGKDADSIPRVKPLKYAYEKEIVMYAHFKKLVYFSTECVFAPNAYRGHARAFLKDLERIRPSVIMDIIHSGEQLSFKDTVKKPLRGKCNRCGFVSSQQPCKACVLLEGLNRGLPKLGVGKKSKANRMIAAQNSLRQSANLVKTDF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_TREPA
Sequence: MNIDVLTLFPAIPRVYFSTSIMARAVSDGIIHYNIVNIRDFAHDKHKHCDAPPYGGGPGMLMRSEPLGKALDSVDAPKKRVVYVTPSGKLFEQGYARSLAQERALVLICGRYEGIDQRIIDEYVDDEVCIGNYVLSSGEIAALVLIDAVSRCVSGVIRHESLEEESFVNSLVEYPQYTRPRCFHNRDVPPVLLSGHHAHIRTWRLARQIEKTRRNRPDLLSAARASAAWTQEAESLLKELDYELPPHPTN
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_NITOC
Sequence: MSSSYWAVVPAAGVGKRMEADIPKQYLPLMGKTVIEHTLARLLQHPRIQAVVVAVSSEDRWWSERLFQDNERIIRVTGGAERCHSVRNGLESLMALAAPEDWVLVHDAARPCLRKEDIDRLIETLHDHPMGGLLALPISDTVKRADAEGSVMETVDRKGLWRAMTPQMFPLAKLYNSLREAIAAGVQVTDEASAMEWAGFSPRLIEGYSDNIKITHPQDLAQAEVFLKRQERGE
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: MTA_SALSA
Sequence: MDPCECSKTGSCNCGGSCKCSNCACTSCKKASCCDCCPSGCSKCASGCVCKGKTCDTSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein A, MT-A.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: FABH_LEVBA
Sequence: MKFENFNILATAGYTPERVVPNSELTTMMTTSDEWIVQRTGIHQRHVVTAERTSDLCTRVAQQLLQRSGLQATDIDYIVVATMSPDYQTPAVSAQVQGNIGATKAVALDVNAACSGFVYGLQVVHRLLMGDSPKTALLIGGETLSRLVDWQDRSTAVLFGDGAGGVVLTSALAQDGAFIAADYRTMGEQGRYLTAGANGVDSPFASDPQPVLPFFKMNGRRVYNFAIKQVPASLRRVLDQGHLAVTDVDYFILHQANQRIIERIAEDLTGSMAQFPVNIGQYGNTAAASEPLLLNQLVTSHVIKRGDVLALSGFGGGLTIGTMILRY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJJB_ECOLI
Sequence: MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGSIGHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export (PubMed:28673128).  Contributes to succinate production under both aerobic and anaerobic conditions (PubMed:28673128).
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YQGF_ECOBW
Sequence: MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNIIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVEARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_BRUAB
Sequence: MSTGFFGDIQKVRYEGPESDNPLAFRHYNADEIVLGKRMEDHLRFAVAYWHSFAWEGGDPFGGRTFDRPWFSNEIDAAKLKADVAFEFFSLLGAPYYCFHDADVRPEGRNFAENTRYLNEIVDIFEKKQAETGMKLLWGTANLFSNRRYMAGAATNPDPDVFAFAAATVKTCIDATKRLGGENYVLWGGREGYETLLNTDLSRELDHMGRFLSLVVEYKHKIGFKGTILIEPKPQEPTKHQYDYDVATVYGFLKRYGLENEVKVNIEQGHAILAGHSFEHELALARTLGIFGSIDMNRNDYQSGWDTDQFPNNVPEMALAYYQVLLAGGFTTGGTNFDAKLRRQSLDPQDLLIGHIGGMDCCARGLKAAARMLEDGALSKPLDERYAGWNGEFGKRLLSGLSLDQIAGEVEAKDINPQPKSGRQEYLENIVNRYV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_PARMW
Sequence: MPLLNSLATPYAEALLQVTEARGESQTVADQCKQLLEIWDSSADFRNAMVSPVLEPDAKKMALQALVGEQVTPSMLNLLKVLADRQRLLAFDAVMLRYLELYREQQGITLAEVRSAQTLTEDQQAALSKKVQAMAGTNMVDIDLSVDPSLIGGFVVSLGSQVIDASLAGQVRRLGLALAKAS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: ACCD_BACC2
Sequence: MLRDLFVKKKKYAAIPSEQVRKDVPDGVMTKCPECKKIMYTKELLKNLKVCVNCGYHHPMNAWERLDSILDEGSFREYDKEMVSLNPLEFPGYEEKLESDRKKTELNEAVVTGEGTIDDMLVVVAVMDSRFRMGSMGSVVGEKIARAVEKAYDLQVPFIIFTASGGARMQEGILSLMQMAKTSVALKKHSNAGGLFISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRVIEQTVREKLPEDFQTAEFLLDHGQLDAVVHRDDMRESLRKILEVHQGGGMAVWQS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_BORHD
Sequence: MSISPQEVKKLRDATGAGFGDCKKALDAVGGDFELAKKKLREMGIASADKRSGRDAKEGRVFSYVNKERVGLLLISCETDFVAMNGDFVTFGNSLIKQLVESGKDSLDEQQELEIKNLAATIKENIHVSKIYISNIASNELVKNYLHGEQSKIGVFIKLRVDDVLKIEDGSLNSLTMDLALHVAAFAPLYLSVGDVCPNYIKEQEEVFMKQMEASGKPENVIKGIVSGKLKKHLGEITLLEQGFVKDDKLTVKEKIEEVSKSILTKIEIIDFKYFSVG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBMC_SALAR
Sequence: MDYEIRQEQKRKIAGFHMVGPWEHTVKQGFKQLMMWVDGKQIVPIEWIAVYYDNPDEVPAEKLRCDTVVSVAENFVLPDNSEGVIVTEIEGGEYATAVARVEDHDFATPWYQFFDALLQDSAYQITSEPCFETYLNNGVEDGYWDIEMYIPVRRK
What is the function of this protein?
Inhibits the supercoiling activity of DNA gyrase.  Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase.  It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
What are the official names of this protein?
DNA gyrase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_LISMF
Sequence: MLTMDDIVREGHPALREVATEVTFPLSDEEKKLGREMLEFLINSQDEELAEKYGLRGGVGIAAPQLAVTKRFLAIHVHDEKDRLYSYVLYNPKIRSHSVQQACLSGGEGCLSVDREVPGYVVRSERVTIDAFDENGTPLKLRFKGYPAIVIQHEIDHLNGIMFYDHINKENPSYLPPDVDVFG
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: Y608_TREPA
Sequence: MADPSACVFRSLRIPGHKPLTWCAKCSTMCPRVPCGSVSVPCAFCTISFRRKCPMQQRFFLLGVCAFAFGVPVFPQQGTDPSVGAQASAGDGGMMTVEQAYLNSAEGVVIKEMVESRGHDSKVLALQYIQEALEGGRGSDDLQEALSRLATAGLFRVIREQGRVINDFPDIRLRACELLARLPSARTKDALIQVMCADREPSVVRAAVKSLGEVGINEQDETTATIGWISRKFSAINPTGSLALEILNTYERLAPTVRDRRAVVESIMDIAADGRYAAAVRARALEVVKGVVSGGK
What are the official names of this protein?
Uncharacterized protein TP_0608.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MYF6_RAT
Sequence: MMMDLFETGSYFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPQEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAINYIERLQDLLHRLDQQEKMQELGVDPYSYKPKQEILEGADFLRTCSPQWPSVSDHSRGLVITAKEGGASVDASASSSLQRLSSIVDSISSEERKLPSVEEVVEK
What is the function of this protein?
Involved in muscle differentiation (myogenic factor).  Induces fibroblasts to differentiate into myoblasts.  Probable sequence specific DNA-binding protein.  May play a role in controlling terminal differentiation events.
What are the official names of this protein?
Myogenic factor 6, Myf-6, Muscle-specific regulatory factor 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: THC1_TETTS
Sequence: MKKILIGLIIGLFLFSSVNASVNLTEVQNAISIQQGINWAEVHNNTWYYPPYLGEMFISEYYFELLVLNWTHKSAFNATYFTERLLQTQFEDGSWEQVREQNLETGQLDATVFNYWYLKSINNNPKIEAALQKARKWIVAQGGIEATQTMTKFKLAAFGQYSWEDLWYVPLFIFKQNGIFKYTYVKDIVAQWVYPHLTALAYLRYQRTVFNVPVADLRELWINYPKNGIKISPREYSTLNPDSDLLILMDEIFKLKQPLGSFGAYTISTLLTLMSFKDFQSKHPHLYQNEIQKAYEDGYYFVEFNYFNFREAYHGSLDDGRWWDTILISWAMLESGQDKERIFPIVQNMVKEGLQPKKGIGYGYDFEYAPDTDDTGLLLVVMSYYKEAFQKQIPETIEWLFSMQNDDGGYPAFDKGKNEDNLLFKFAFNMAGIANSAEIFDPSCPDITGHIMEGLGEFGYQANHPQIQNMIKYQRKTQNKWGSWQARWGVNYIMAVGAVVPGLARVNYDLNEQWVQNSINYLLNKQNKDGGFGECVLSYNDPEKWNGIGKSTVTQTSWGLLALLEVYNQNEQIKHAADRAAQYLLDQFKRDDNTFYDHSTIGTGHRGLLYLQYPSYAQSFPLVALNRYQKISQGQYHFSKNLYNGNGEPVQKQNI
What is the function of this protein?
Squalene cyclase that catalyzes the oxygen-independent cyclization of squalene into tetrahymanol, a triterpenoid sterol with five cyclohexyl rings that is involved in membrane integrity, permeability and fluidity.
What are the official names of this protein?
Squalene-tetrahymanol cyclase THC1, STC.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: CYNS_ASPFC
Sequence: MSLATLDATQHPNLPASAATLFKAKAQKKLSFEQIAQHIGRNEVATAALFYGQAKASPEDIQKLSELLNISPQVLEEQLSGFPDRGRSVEMPPKEPLIYRLYEIVQNYGYAYKAVLNEKFGDGIMSAISFSTKVEKETDADGNNWAVITLRGKW
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: HEMA_MONPV
Sequence: MTQLPILLLLISLVYATPSPQTSKKIGDDATISCSRNNTNYYVVMSAWYKEPNSIILLAAKSDVLYFDNYTKDKISYDSPYDDLVTTITIKSLTAGDAGTYICAFFMTSTTNDTDKVDYEEYSIELIVNTDSESTIDIILSGSTPETISEKPEDIDNSNCSSVFEITTPEPITDNVDDHTDTVTYTSDSINTVNASSGESTTDEIPEPITDKEEDHTVTDTVSYTTVSTSSGIVTTKSTTDDADLYDTYNDNDTVPPTTVGGSTTSISNYKTKDFVEIFGITTLIILSAVAIFCITYYICNKHPRKYKTENKV
What is the function of this protein?
Prevents cell to cell fusion by interacting with and directing the viral OPG040 protein on the host plasma membrane.  The OPG185-OPG040 complex associates with components of the entry fusion complex (EFC) presumably to avoid superinfection and syncytium formation.  Via its interaction with C3/VCP protein, protects the infected cell and probably also the extracellular enveloped virus from complement attack.
What are the official names of this protein?
Protein OPG185, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG185 family.