PharMolix/UniProtQA huggingface dataset:
Protein: YA44_HELPJ
Sequence: MLISIAFLLVLCLLNYSSFRMLKSFLTLKKISRYAYLGFFILLSAGEATFVFYRNVMPSHLFVLTSACSFVSFIAFVFSLSFYGFSYSVEKIDFLPSRRKGLKNFLRIGFYLALLGYFWRGFYEGLARPKIKETPIYLDKLDKELKIILLTDMHVGSLLQKDFVNYIVEEVNQKEVDMVLIGGDLVDENIEKVKSFLLPLNNLKSTHGTFYVPGNHEYYHGIEPILSFLNTLDMTILGNECVHLGGINLCGVYDYFARKRQDFAPDIDKALKKRDSSKPTILLAHQPKQIRSLKESHSIDLVLSGHTHAGQIFPFSLLVKLAQTYLHGLYKHSGTTQIYVSSGAGYWGIPLRFLAPSEIAYLRLLPKNQA
What are the official names of this protein?
Uncharacterized metallophosphoesterase jhp_0380.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily.
Protein: LGT_STRT1
Sequence: MLATIDPIALRLGPISIHWYAICIVSGLLLAVYLAQRLAPEKGINPEHILDFILLAFPIAIVGARLYYVIFQWSYYSQNPSEIFAIWNGGIAIYGGLIAGAAVLYWFAKRHAIAVLDFLDIAAPGVMIAQSIGRWGNFVNQEAYGKAVSQLNYLPEIIRQQMFINGSYRVPTFLYESLWNLVGFSIILGLRYFNKGLRQGDVTSFYLIWYGLGRFVIEGMRTDSLMFVGLRVSQWVSISIIILGAVLLYFRKQRQKADYKMKN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNJB5_BOVIN
Sequence: MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRGLYDQYGEEGLKTGGGSSGGSSGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSARPFSGFDPDDMDVDEDDDPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDGRVIPLPCNDVIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS
What are the official names of this protein?
DnaJ homolog subfamily B member 5.
Protein: NH2L1_CAEEL
Sequence: MADDGVNPKAFPLADTNLSQKLMDLVQQAMNYKQLKKGANEATKTLNRGISEIIVMAADAEPLEILLHLPLLCEDKNVPYVFVRSKAALGRACGVTRPVIAASITQNEGSQLKSQIQKIKEDVEKLLI
What is the function of this protein?
Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly.  The protein undergoes a conformational change upon RNA-binding (By similarity).
What are the official names of this protein?
NHP2-like protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y1607_PSEA7
Sequence: MLMVISPAKTLDYETPPVTQRFTQPQYLDHSQELIQQLRQLTPLQISELMKLSDKLAGLNAARYASWHPDFTPQNAKQALLAFKGDVYTGLDAESFSEDDFAFAQEHLRMLSGLYGVLRPLDLMQPYRLEMGTRLANARGKDLYAFWGERISQWLNEALAAQGDDVLLNLASNEYFGAVKRKALQARIIDTEFKDLKNGQYKIISFYAKKARGMMARYVVRERLRDPAGLKDFNAHGYYFSAEQSGPEQLVFLRDAPQD
What are the official names of this protein?
UPF0246 protein PSPA7_1607.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: PRIB_BORPE
Sequence: MNTLELSARVLECGAMRHTPAGLPALELLLVHESEVVEAGHPRRVELTISAVALGDLALLLADTPLGTEMQVQGFLAPARKDSVKVKLHLQQARRIAGSMGRDPLVG
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: RS8E_META3
Sequence: MGIWQGQSRRKATGGKYKIVVKKHKKEMGRESAETHLTDDTKIKIVRVAGGNKKVKLLRTNYANVMDPKTNTCKKVSISNVVGNDANKHYIRRNIITKGAIIETEMGKAKVTSRPGQSGIVNAILINE
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: NSRR_ECOUT
Sequence: MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: RLX3_STAAU
Sequence: MATTKISSTKSTSRAINYAEKRAEEKSALNCDIDYAKSSFKATREMYGKTDGNEGHVVIQSFKPNEVTPEQCNQLGLELAEKIAPNHQVAVYTHNDTDHVHNHIVINSIDLETGKKFNNNKKALHDIRQANDEICVSHNLSIPEEKAKLRYTQAEYSVLNKGKTSWKDEIRHAIDQSQAASYEELGNDLQQNGIKIERITDKTITYRHLEEDKKVRGKKLGEDYDKGGLEIGFNRQNEQREEQARQRELEQARREKIKRDKEREKEWARFNRSTQAIRQNRERSEREERERERKARELEEQNRRAREERARQERENKHTHEKTRGFDLEL
What is the function of this protein?
This protein is probably required for relaxation complex formation and plasmid mobilization by conjugative plasmids.
What are the official names of this protein?
Protein rlx.
Protein: APAG_ENT38
Sequence: MIDSPRVCVQVQSVYIESQSTPDDERFVFAYTVTIRNLGRMPVQLLGRYWLITNGNGREIEVQGEGVVGEQPHIAPGEEFQYTSGAVIETPMGTMQGHYEMVDVDGNAFRVAVPVFRLAVPTFIH
What are the official names of this protein?
Protein ApaG.
Protein: NCAP_I83A1
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIGGIGRFYIQMCTELKLNDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYKRVDGKWMRXLVLYDKEEIRRIWRQANNGDDATAGLTHIMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVLELIRMIKRGINDRNFWRGENGRKTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLTFLARSALILRGSVAHKSCLPACVYGPAVASGYDFEKEGYSLVGIDPFKLLQTSQVYSLIRPNENPAHKSQLVWMACNSAAFEDLRVSSFIRGTKVIPRGKLSTRGVQIASNENMDTMVSSTLELRSRYWAIRTRSGGNTNQQRASAGQISIQPTFSVQRNLPFDKTTIMAAFTGNAEGRTSDMRAEIIKMMESARPEEVSFQGRGVFEFSDERAANPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: EFP_FRAP2
Sequence: MASYSTNEFKGGLKILIDGNPMVIVENEFVKPGKGQAFNRVKLKNLLNDRVVEKTFKSGESVEAADVEELNAVYSYFDGDSYVFMHPETFEQYMVSQEALGETKKWLKDQDEYQIILFNGQPISIIAPNFVNLEIVETDPGLKGDTAGTGGKPATLSTGAVVRVPLFVQTGEIIKVDTRTSTYVSRVKD
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGP16_ARATH
Sequence: MASRNSVTGFALFSFVFAVILSLAGAQSLAPAPAPTSDGTSIDQGIAYLLMVVALVLTYLIHPLDASSSYSFF
What is the function of this protein?
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death.
What are the official names of this protein?
Arabinogalactan protein 16, AtAGP16, Arabinogalactan peptide 16, AG-peptide 16.
What is the protein family that this protein belongs to?
Belongs to the AG-peptide AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: MATP_ECO5E
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVLLSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQRLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_TURTR
Sequence: MNGTEGLNFYVPFSNKTGVVRSPFEYPQYYLAEPWQFSVLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVANLFMVFGGFTTTLYTSLHAYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGLALTWIMAMACAAAPLVGWSRYIPEGMQCSCGIDYYTSRQEVNNESFVIYMFVVHFTIPLVIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVVAFLICWVPYASVAFYIFTHQGSDFGPIFMTIPSFFAKSSSIYNPVIYIMMNKQFRNCMLTTLCCGRNPLGDDEASTTASKTETSQVAPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Signaling mediates the activation of phospholipase C (By similarity).  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Note=Detected on the rhabdomere membrane in the photoreceptor outer segment.
Protein: DDX25_XENLA
Sequence: MAAKFLPRFWRSGSQAELLDFQNNNVVAEGKLDFEHGTLKGKSGRYGDDEEDVRRGHIEDLANHSLLNKLLRRTLVDSPHNVEVLQRDPTSPLFSVKSFEELHLKNELLRGIYAMGFNRPSKIQENALPMMLADPPQNLIAQSQSGTGKTAAFVLAMLSRVDANKKYPQCICLSPTFELALQTGKVVEEMGKFCAGIEVIYALRGNRPGKGSRLEAQIVIGTPGTVLDWCFKLRLITVENISVFVLDEADVMINVQGHSDHSVRVKRSMPKSCQMLLFSATFEDSVWAFAERIVPDPNIIKLKKEELTLKNIQQFYDQCENKEQKYSALCNLYGVITIAQAIVFCQTRKIASWLSQKLSDDGHQVALLSGELPVYDRADMIQRFREGREKVLVTTNVCARGIDVEQVSIVVNFDLPVNVDGSVDFETYLHRIGRTGRFGKKGIAVSLIENFFVYMLKEIEDHFNTKITKLNSMDMDEMGKIWK
What is the function of this protein?
ATP-dependent RNA helicase.
What are the official names of this protein?
ATP-dependent RNA helicase DDX25, DEAD box protein 25, RNA helicase DEADSouth, Xcat3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Also detected in chromatoid bodies of round spermatids.
Protein: HSLU_STAA8
Sequence: MDTAGIRLTPKEIVSKLNEYIVGQNDAKRKVAIALRNRYRRSLLDEESKQEISPKNILMIGPTGVGKTEIARRMAKVVGAPFIKVEATKFTEVGYVGRDVESMVRDLVDVSVRLVKAQKKSLVQDEATAKANEKLVKLLVPSMKKKASQTNNPLESLFGGAIPNFGQNNEDEEEPPTEEIKTKRSEIKRQLEEGKLEKEKVRIKVEQDPGALGMLGTNQNQQMQEMMNQLMPKKKVEREVAVETARKILADSYADELIDQESANQEALELAEQMGIIFIDEIDKVATNNHNSGQDVSRQGVQRDILPILEGSVIQTKYGTVNTEHMLFIGAGAFHVSKPSDLIPELQGRFPIRVELDSLSVEDFVRILTEPKLSLIKQYEALLQTEEVTVNFTDEAITRLAEIAYQVNQDTDNIGARRLHTILEKMLEDLSFEAPSMPNAVVDITPQYVDDKLKSISTNKDLSAFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YC9A_METJA
Sequence: MGVRECVVTRIIKSRPIIACEDVYLHNYTVFIKIRNRTQGFVKYEPIVGYPVNVTVSLKSAVPDLKDIEIWASAMDENGRLINCSKKKTIDIYGNYRKVNLEILFNDSLEGYLIIYAKTGEAVIPLYYKPIMVTYPVVFGLEYNPSDPWANLTLSHNYQVPIKVNATIGKYSKIITIYPYKETKVPFYVGKDRNNITVSIELLNNISTIKKFKKTFYFKKLNKIKTSINETVVNKYN
What are the official names of this protein?
Uncharacterized protein MJ1292.1.
Protein: PRIB_BORPA
Sequence: MNTLELSARVLECGAMRHTPAGLPALELLLVHESEVVEAGHPRRVELTISAVALGDLALLLADTPLGTEMQVQGFLAPARKDSVKVKLHLQQARRIAGSMGRDPLVG
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: KDSB_KORVE
Sequence: MPPRVSRFNLPEPAPRVETGTVKAIAVIPARIASTRLPRKILREIDGRTMLDRVYNAAKGAPMLADVIVATDSQEIMDVCNRHGWNARLTSDQHRSGTDRVHEVAQTVAADVYVNVQGDEPLARPEHLNTLLELMRDETVQVGTLKTPCGKEDVANPNAVKVVTDKTGRALYFSRSTVPYDRDNRGDIAYFKHLGFYAYRKPTLDRFCGWPESSLERSERLEQLRFLENGVDIYVAETPYDTIGVDTEADLKRVEEILRSRN
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GT4A_SOLAA
Sequence: MDNGSNQLHVLFLPYFATGHIIPLVNAARLFVFHAGVKVTILTTHHNASLFRSTIDNDVEDGHSVISIHTLRFPSTEVGLPEGIENFSSASSPELAGKVFYAIYLLQKPMEDKIREIHPDCIFSDMYLPWTVNIALELKIPRLLFNQSSYMYNSILYNLRLYKPHKSKTITSTDSISVPGLPDKIEFKLSQLTDDLIKPEDEKNAFDELLDRTRESEDRSYGIVHDTFYELEPAYADYYQKVKKTKCWQIGPISHFSSKLFRRKELINAVDESNSCAIVEWLNEQEHKSVLYVSFGSVVRFPEAQLTEIAKALEASSIPFIWVVKKDQSAETTCLLEEEKLKNKGLIIRGWAPQLTILDHSAVGGFMTHCGWNSILEAIIAGVPLVTWPVFAEQFYNEKLVEVMGLGVKVGAEVHESNGGVEISSLVIESEKIKEAIEKLMDDSKESQKIREKVIGMSEMAKNAVEEGGSSWNNLTALIDDIKNFTSTTNV
What is the function of this protein?
Glucosyltransferase involved in steroid saponin biosynthesis (PubMed:15821879).  Catalyzes the 3-O-glucosylation of steroidal sapogenins, such as diosgenin, nuatigenin and tigogenin (PubMed:15821879).  Can glucosylate steroidal alkaloids, such as solanidine, solasodine and tomatidine (PubMed:15821879).
What are the official names of this protein?
Nuatigenin 3-beta-glucosyltransferase, Glycosyltransferase 4A, SaGT4A.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: CIDEA_HUMAN
Sequence: MEAARDYAGALIRPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELISKTLDALVIATGLVTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSPPKRSGIARVTFDLYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYSAQVTGQFLIYLGTYMLRVLDDKEERPSLRSQAKGRFTCG
What is the function of this protein?
Lipid transferase that promotes unilocular lipid droplet formation by mediating lipid droplet fusion (PubMed:19843876, PubMed:26118629).  Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage (PubMed:19843876).  Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by promoting directional net neutral lipid transfer from the smaller to larger lipid droplets (By similarity).  The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC (By similarity).  May also act as a CEBPB coactivator in epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein (By similarity).  By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity).  When overexpressed, induces apoptosis; the physiological significance of its role in apoptosis is unclear (By similarity).
What are the official names of this protein?
Lipid transferase CIDEA, Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A.
What is the protein family that this protein belongs to?
Belongs to the CIDE family.
What are the subcellular locations of this protein?
Lipid droplet. Nucleus. Note=Enriched at lipid droplet contact sites. Has been shown to localize to mitochondria, where it could interact with UCP1 and hence inhibit UCP1 uncoupling activity (By similarity). These data could not be confirmed (PubMed:18509062).
Protein: RL32_RUTMC
Sequence: MAVQKSRKTPSKRGMRRSHNALTNPTLSEDQETGEIHLRHHITVDGYYRGKKVIKKTQDIQEINA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: TIM14_SCHPO
Sequence: MSSAILLGVGIAATAAAGKIGVDAFRKYRNLNGGVKAFLKGGFESKMSRAEAIQILSLNNRTLTRQKIKEAHRRLMLANHPDRGGSPYVASKVNEAKSLLDADRSIRKFSSWALPVSKQRSMPSVLEAVKWLEYSSIPKA
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  In the complex, it is required to stimulate activity of mtHSP70 (ssc1) (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim14, Presequence translocated-associated motor subunit pam18.
What is the protein family that this protein belongs to?
Belongs to the TIM14 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SYL_BORPE
Sequence: MQERYQPNSVEAAAQQTWQARDAYLVHEHAKNPDGSEKPKFYACSMLPYPSGKLHMGHVRNYTINDMMARQLRMRGYNVLMPMGWDAFGMPAENAAIKSKVPPAKWTYDNIAYMKKQMKAMGLAIDWSREMCACDPKYYKWNQWLFLKMLEKGIAYRKTQVVNWDPVDQTVLANEQVIDGRGWRSGAPVEKREIPGYYLRITDYAEELLDQVSTNLPGWPERVRLMQENWIGKSEGLRFAFPHRIAGADGKLIQDGKLYVFTTRADTIMGVTFCAVAPEHPLATHAAQSNPALAAFVEQCKLGGTTEAEMATREKEGMPTGLTVTHPLTGAEIDVWVGNYVLMTYGDGAVMGVPAHDERDFAFARKYGLPIRQVVALEGKTYSTDAWQEWYGDKQAGRTVNSGKYDGLAYQAAVDAIAADLAAQGVGEKQTTWRLRDWGISRQRYWGTPIPIIHCADCGPVPVPEQDLPVVLPDDLIPDGSGNPLAKNEAFLSCSCPRCGKPARRETDTMDTFVDSSWYFMRYTSPDNDQAMVDARNDYWMPMDQYIGGIEHAVLHLLYARFWTKVMRDLGLLNFDEPFTKLLCQGMVLNHIYSRKTPQGGIEYFWPEEVDNVYDAKGAIVGAKLQRDGSEVNYGGVGTMSKSKNNGVDPQSLIDTLGADTARLFVMFASPPEQTLEWSDSGVEGANRFLRRLWALGYAQREAVGRGLATGADWAQAPAPVKELRREVYGLLKQADYDYQRIQYNTVVSACMKMLNAIDDAPLPEGPAADAARAETLGLLLRVLYPVVPHITWHLWQDLGYAEHLGDLLDAPWPHVDEAALVADEIELMLQVNGKLRGSIRVAAKAPKEDIERIAAAQEEVARFLEGRPPKRVIVVPGKLVNVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIMA1_PORG3
Sequence: MKKTKFFLLGLAALAMTACNKDNEAEPVTEGNATISVVLKTSNSNRAFGVGDDESKVAKLTVMVYNGEQQEAIKSAENATKVEDIKCSAGQRTLVVMANTGAMELVGKTLAEVKALTTELTAENQEAAGLIMTAEPKTIVLKAGKNYIGYSGTGEGNHIENDPLKIKRVHARMAFTEIKVQMSAAYDNIYTFVPEKIYGLIAKKQSNLFGATLVNADANYLTGSLTTFNGAYTPANYANVPWLSRNYVAPAADAPQGFYVLENDYSANGGTIHPTILCVYGKLQKNGADLAGADLAAAQAANWVDAEGKTYYPVLVNFNSNNYTYDSNYTPKNKIERNHKYDIKLTITGPGTNNPENPITESAHLNVQCTVAEWVLVGQNATW
What is the function of this protein?
Structural subunit of the major fimbriae.  These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome (PubMed:9786913, PubMed:12593606, PubMed:15165251, PubMed:17675496, PubMed:17526848, PubMed:20530728, PubMed:27062925).  They play an important role in the invasion of periodontal tissues (PubMed:12593606).  Fimbriae and their constituents are major virulence factors.  FimA proteins from different strains have highly divergent sequences, and this has been used for classification (PubMed:23809984).  The sequence-based classification correlates with pathogenicity (PubMed:17675496).
What are the official names of this protein?
Major fimbrium subunit FimA type-1, Fimbrillin, Fimbrilin, Major fimbrial subunit protein type I.
What is the protein family that this protein belongs to?
Belongs to the bacteroidetes fimbrillin superfamily. FimA/Mfa1 family.
What are the subcellular locations of this protein?
Fimbrium. Cell outer membrane. Note=Synthesized as palmitoylated precursor. The lipidated propeptide is removed during processing to the mature protein.
Protein: NUOK_CHRVO
Sequence: MLTLTHFLVLAAILFAISVLGIFLNRKNLIILLMAIELMLLAVNFNFIAFSHYLSDSAGQIFVFFILTVAAAESAIGLAILVVLFRNLQSINVEDLGSLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ALDX_SPOSA
Sequence: MVGTTTLNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIKEAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLGNNTVGAPLLVQHPEIKRIAEKNGCTPAQVLIAWAIVGGHSVIPKSVTPSRIGENFKQVSLSQEDVDAVSKLGEGSGRRRYNIPCTYSPKWDINVFGEEDEKSCKNAVKIK
What is the function of this protein?
Catalyzes the asymmetric reduction of aliphatic and aromatic aldehydes and ketones to an R-enantiomer.  Reduces ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate.
What are the official names of this protein?
Aldehyde reductase 1, ALR 1, Alcohol dehydrogenase [NADP(+)], Aldehyde reductase I.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: OAT2_STAS1
Sequence: MSRSEEIIEVTNHYGAQNYVPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKEQADKVTLVSRAFHSENLGEWYEKICKLSGKAKALPMNTGAEAVETALKAARRWAYDVKNIQPDKAEIIAFNGNFHGRTMAPVSLSSEPEYQRGYGPLLDGFRKVDFGDIEAVKAAINENTAAILIEPIQGEAGINVPPEGYLKQIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVLPISVVLADEEVLGVFTPGSHGSTFGGNPLACAVSNAALDVIIDEDLPGRSLELGDYFKSELEKIDHPAIKEVRGRGLFIGIELNEAARPFCESLKEQGLLCKETHDTVIRFAPPLIISKEELDFALDKVRSVFE
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase 2, OAT 2, Ornithine--oxo-acid aminotransferase 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.