PharMolix/UniProtQA huggingface dataset:
Protein: CCR3_CHLAE
Sequence: MTTSLYTVETFGPTSYDDDMGLLCEKADVGALIAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLFTLPFWIHYVREHNWVFSHGMCKVLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLVALPEFIFYGTEELFPETLCSAIYPQDTVYSWRHFHTLKMTILCLALPLLVMAICYTGIIKTLLKCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILISTYQSILFGLDCERSKHVDLVVLVTEVIAYSHCCVNPVIYAFVGERFRKYLRHFFHRHVLMHLGRYIPFLPSEKLERTSSVSPSTAEPELCIVF
What is the function of this protein?
Receptor for a C-C type chemokine.  Binds to eotaxin, MCP-3, MCP-4 and RANTES and subsequently transduces a signal by increasing the intracellular calcium ions level.
What are the official names of this protein?
C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPO13_SACS2
Sequence: MVSGMSTDEEKEGTSDEEVNEEKEVEETSEDEFPKLSIQDIELLMRNTEIWDNLLNGKITLEEAKKLFEDNYKEYEKRDSRRKAKKAVSKKVKKTKKKEKSVEG
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Probably binds dsDNA.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo13.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo13 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPF_HAEIN
Sequence: MNITWNWYEQLESAHARAFTVAKATKAEVLDTIRWATEQAIANGTGEREYIKKLEPMLKELGWWGKAKDENGNEVQLGSPRRLRTILRTNKITAYHAARYAQQMENVDEQPYWRYVAVNDSRTRASHLALHGKIYRADDPIWQTMYPPNDWGCRCRVEALSEYAVQSRGLKISSSDGEMEMEEAVVGIDKDTGEEIRTTVSKIKTDQGEMKVGAGWNYNVGSAAFGTDVAVLRKLQQVKNRELRQQTIQAINNSEARHKAFADWVLANLGKRGASARYMSAGLVTTEIAEAVTEITQGGKNAELVLVMSEKRLAHANSDKHHEGGVGLTAEEYASISRIVANPSLVLWDTLEGHNNLIYINQERTIQVIVDVPNKHSIKPKEKVDAIINAYKVDMNNVKRQLSGGNYVLLKGKL
What is the function of this protein?
Involved in virion morphogenesis.
What are the official names of this protein?
Mu-like prophage FluMu F protein.
What is the protein family that this protein belongs to?
To phage Mu protein F.
Protein: PI10A_PLARH
Sequence: MKTALFLVFALAFIAVEGKFSKACSKPGQTVLAPDGCNHCRCSKNGIIMGCTKKMCPPRTMKQSCKPGATFKHKDGCNTCKCSDDGKSARCTARLCW
What is the function of this protein?
Inhibits trypsin activity and prophenoloxidase (PPO) activation, an enzyme essential for both clotting and insect innate immune responses.  It does not inhibit activity of chymotrypsin and protease K, and has no effect on phenoloxidase (PO) activity.
What are the official names of this protein?
U-reduvitoxin-Pr10a, U-RDTX-Pr10a, Venom pacifastin domain peptide Pr10a.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I19 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FETP_VIBPA
Sequence: MSRTVFCARLKKEGEGLDFQLYPGELGKRIFDNISKEAWAQWQHKQTMLINEKKLNMMDPEHRKLLETEMVNFLFEGKDVHIEGYTPPSE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: RL28_GEOSW
Sequence: MAKCFVTGKKKSFGNSRSHAMNANKRTWKVNLQKVRILVDGKPKRVWVSARALKSGKVQRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: GLMM_EXIS2
Sequence: MGKYFGTDGVRGVANVELTPELAYRLGRTGGYVLTKHESTRPKVLIGRDTRVSGQMLENALIAGLLSIGAEVMRLGVISTPGVAYLTKTMDATAGVMISASHNPVEDNGIKFFGSDGFKLDDATELEIEGLLDEAEDTLPRPSGKELGFVHDYYEGAQKYLHMLRQTSDEDFSGIHVAIDGAHGATSSLAPRLFGDLEAEVSTIGTTPNGLNINEGVGSTHPEHLADFVLEKGADVGLSFDGDGDRLIAIDENGKIVDGDKIMFICGKYLNEIGRLKDNTIVATVMSNLGFHKTVAEHGMTALQTAVGDRYVVEEMRKNNYTLGGEQSGHIIFMDYSTTGDGMLSGVQLLQIMKATGKKLSELAAEMPVFPQRLVNIRVSDKNGAMNGPAVQAIIAEVEAEMAGNGRILVRASGTEPLVRVMAEAPTQEACDMYVERIANVVRENYALQEN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: TILS_SYNJA
Sequence: MARLSPLHLRVQCAIRERQLLRPGQRLLVAFSGGQDSFSLLQILRDLQPRWRWQIFVLHCDHRWSADETACAQFLQGWLQQQGLPHAVETADPIRWDEAGARAWRYQQLDKWARTWSCEAVATGHTASDRAETFLWNLLRGTGAAGLVSLDWQRRLDERDPTSAWLVRPLLGLSRWETEEFCRQYQLPVWPDRSNQDLAHGRNRLRLEVMPYLKQHFNPQLEAALNRAATLLQAEHELVVAQAAQLWLQVYEPALPGLRRDPLRAAPLALQRQVMFQFLSLLLPHHPTFEQVEAGIRLLKAGRRSRSPDYPGGGWLEVRGDCVVWVAASQPASFVP
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AWAT1_MOUSE
Sequence: MSCSMKTEHLQSLSLLQWPLSYVAMFWIVQPLLICLLFTPLWPLPTVYFVWLLLDWKTPDKGGRRSDWVRNWNVWNHIRDYFPITILKTKDLSPSENYIMGVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATLSWFFKIPIIRDYIMAKGLCSVSQASIDYLLSHGTGNLVGIVVGGVGEALQSVPNTTTLLLKKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHEDSRMFKFQSLFRRIFGFYCCVFYGQGFHQDCKGLLPYHKPIITVVGEALPLPQVKNPSPEIVDKYHALYMDALYKLFEQHKVQYGCSNTQKLIFL
What is the function of this protein?
Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters (By similarity).  Shows a strong preference for decyl alcohol (C10), with less activity towards C16 and C18 alcohols (By similarity).  Shows a strong preference for saturated acyl-CoAs (By similarity).
What are the official names of this protein?
Acyl-CoA wax alcohol acyltransferase 1, Diacylglycerol O-acyltransferase 2-like protein 3, Long-chain-alcohol O-fatty-acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL5_STRPI
Sequence: MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEAVSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTTANTDEESRALLTGLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: LTOR4_DROPS
Sequence: MDKEKLIAPNQMGYLILKDDGNLLDSGGDLKNDDRSANVIMGLLNLTDSIDEDFMPNSSCERITIDYDQHYYSICMSNRRIYVVKLSKTHTQNGATTSSSSSTSYNDAAEGNNISSSTVLA
What is the function of this protein?
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids.  As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity).
What are the official names of this protein?
Ragulator complex protein LAMTOR4 homolog, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR4 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: POL2_CPMVS
Sequence: MFSFTEAKSKISLWTRSAAPLNNVYLSYSCRCGLGKRKLAGGCCSAPYITCYDSADFRRVQYLYFCLTRYCCLYFFLLLLADWFYKKSSIFFETEFSRGFRTWRKIVKLLYILPKFEMESIMSRGIPSGILEEKAIQFKRAKEGNKPLKDEIPKPEDMYVSHTSKWNVLRKMSQKTVDLSKAAAGMGFINKHMLTGNILAQPTTVLDIPVTKDKTLAMASDFIRKENLKTSAIHIGAIEIIIQSFASPESDLMGGFLLVDSLHTDTANAIRSIFVAPMRGGRPVRVVTFPNTLAPVSCDLNNRFKLICSLPNCDIVQGSQVAEVSVNVAGCATSIEKSHTPSQLYTEEFEKEGAVVVEYLGRQTYCAQPSNLPTEEKLRSLKFDFHVEQPSVLKLSNSCNAHFVKGESLKYSISGKEAENHAVHATVVSREGASAAPKQYDPILGRVLDPRNGNVAFPQMEQNLFALSLDDTSSVRGSLLDTKFAQTRVLLSKAMAGGDVLLDEYLYDVVNGQDFRATVAFLRTHVITGKIKVTATTNISDNSGCCLMLAINSGVRGKYSTDVYTICSQDSMTWNPGCKKNFSFTFNPNPCGDSWSAEMISRSRVRMTVICVSGWTLSPTTDVIAKLDWSIVNEKCEPTIYHLADCQNWLPLNRWMGKLTFPQGVTSEVRRMPLSIGGGAGATQAFLANMPNSWISMWRYFRGELHFEVTKMSSPYIKATVTFLIAFGNLSDAFGFYESFPHRIVQFAEVEEKCTLVFSQQEFVTAWSTQVNPRTTLEADGCPYLYAIIHDSTTGTISGDFNLGVKLVGIKDFCGIGSNPGIDGSRLLGAIAQGPVCAEASDVYSPCMIASTPPAPFSDVTAVTFDLINGKITPVGDDNWNTHIYNPPIMNVLRTAAWKSGTIHVQLNVRGAGVKRADWDGQVFVYLRQSMNPESYDARTFVISQPGSAMLNFSFDIIGPNSGFEFAESPWANQTTWYLECVATNPRQIQQFEVNMRFDPNFRVAGNILMPPFPLSTETPPLLKFRFRDIERSKRSVMVGHTATAA
What is the function of this protein?
Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
RNA2 polyprotein, Genome polyprotein M, M RNA polyprotein, Middle component RNA polyprotein, P2.
What are the subcellular locations of this protein?
[VP58]: Host nucleus. SUBCELLULAR LOCATION: [Movement protein]: Host cell junction, host plasmodesma. Note=Assembles in tubules that are embedded within modified plasmodesmata. SUBCELLULAR LOCATION: [Large capsid protein]: Virion. SUBCELLULAR LOCATION: [Mature small capsid protein]: Virion.
Protein: NDHK_BRADI
Sequence: MSLIEFPLLDQTSSNSVISTTPNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDALTKLRKKISREIVEDRIRSQNKNRCFTTSHKLYVRRSTHTGTYEQELLYQSPSTLDISSENFYKSKSIVPSYKLVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RL19_LACCB
Sequence: MNPLIQEITKKQLRDDIPDFRPGDNVRVHAKIVEGERERIQLFEGVVIKRHGVGISATYTVRKISNGVGVERTFPLHSPRVEKIEVTRHGQVRRAKLYYLRALRGKAARIREKRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: GCS21_MYCS2
Sequence: MSSLPADSRIDFAGSPRPTVGVEWEFALVDAKTRELSNEAAAVIAEIGENPHVHKELLRNTVEIVTGICENSGEAMGDLCDTLSTVRRAVRGRGMELFCAGTHPFGKWSAAQLTDAPRYAELIKRTQWWGRQMLIWGVHVHVGVSSAHKVMPIISSLLNQYPHLLALSASSPFWDGEDTGYASNRAMMFQQLPTAGLPFQFQTWHEFEGFVHDQKKTGIIDHLSEIRWDIRPSPQLGTVEVRIFDGVSNVRELSALVALTHCLIVDLDRRLDAGEQLPVMPPWHVQENKWRAARYGLDAVIILDADSNERLVTEDLDDLLNHLEPVAASLHCADELAAVEDIYRLGGSYQRQRRVAEENDGDLREVVDALIGELEL
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-1, Gamma-glutamylcysteine synthetase 2-1, GCS 2-1, Gamma-GCS 2-1.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: CGT_FRAAN
Sequence: MGSESLVHVFLVSFIGQGHVNPLLRLGKRLAAKGLLVTFCTAECVGKEMRKSNGITDEPKPVGDGFIRFEFFKDRWAEDEPMRQDLDLYLPQLELVGKEVIPEMIKKNAEQGRPVSCLINNPFIPWVCDVAESLGLPSAMLWVQSAACLAAYYHYYHGLVPFPSESDMFCDVQIPSMPLLKYDEVPSFLYPTSPYPFLRRAILGQYGNLEKPFCILMDTFQELESEIIEYMARLCPIKAVGPLFKNPKAQNAVRGDFMEADDSIIGWLDTKPKSSVVYISFGSVVYLKQEQVDEIAHGLLSSGVSFIWVMKPPHPDSGFELLVLPEGFLEKAGDRGKVVQWSPQEKILEHPSTACFVTHCGWNSTMESLTSGMPVVAFPQWGDQVTDAKYLVDEFKVGVRMCRGEAEDRVIPRDEVEKCLLEATSGSKAAEMKQNALKWKAAAEAAFSEGGSSDRNLQAFVDEVRRISASLNSKSSAVGYVKSKINGVVEYVDSKLNGKAAPVEEANTRTNGIAKVEQPKAANGKVEIAELTPINGKVEIAELKPINGKVELVES
What is the function of this protein?
Broad spectrum multifunctional glucosyltransferase.  Catalyzes the formation of cinnamic acid and p-coumaric acid glucose esters during fruit ripening.  Accepted substrates range from derivatives of cinnamic acid and benzoic acid to heterocyclic and aliphatic compounds, resulting in the formation of O- and S-glucose esters and O-glucosides.  May also be involved in detoxification of xenobiotics.
What are the official names of this protein?
Cinnamate beta-D-glucosyltransferase, UDP-glucose:cinnamate glucosyltransferase, FaGT2.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: PABP2_DICDI
Sequence: MTDNNNGEIVEDKDNEKLKGEDNINNHISNHNNTEETSFEDPELEEMKKRFREMEEEAKKLTELQNNLESNITGNNGVGIGGNIGGGGGLMNTDQEEIDSRSVYVGNVDYKSTHDQILAYFQSCGTVNRITILSDKTTGHPKGCCYVEFVNKESIINAMALNDSFFNERQLKITPKRTNLPYYMRQGVLPPGRGGFRGGRGRGGIRGGIRGGRGRGNFYQPY
What is the function of this protein?
Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product.
What are the official names of this protein?
Polyadenylate-binding protein 2, PABP-2, Poly(A)-binding protein 2, Poly(A)-binding protein II, PABII.
What are the subcellular locations of this protein?
Nucleus.
Protein: STAP1_MOUSE
Sequence: MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLVKRSDHQEYKHYWTELRGTTLFFYTDKKSTIYVGKLDIIDLVCLTGQHSTEKNCAKFTLVLPKEEVHVKTENTESGEEWRGFILTVTELTVPQHVSLLPGQVIRLHEVLEREKKRRIETDQLPLMPPEKEKEPVQDYADVLNPLPECFYAVSRKEATAMLEKNPSWGNMILRPGSDSKNYSITIRQEIEMPRIKHFKVTRTGNNYTIELEKPVTLPNLFSVIDYFVKETRGNLRPFIHSADDNFGQDPNIEDRSEKFKKNPHNA
What is the function of this protein?
May function as an adapter molecule downstream of KIT in the proliferation or differentiation of hematopoietic stem cells.
What are the official names of this protein?
Signal-transducing adaptor protein 1, STAP-1, Stem cell adaptor protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion.
Protein: CND_CAEEL
Sequence: MSNINEKDLSEFLESNLRSLNDIDDAVATSSAECNYEDYEEFTNSVDLTFFEQDLSGVLKELKKLAESVVISGKKCDIRNIFEESDVATMKFNLFVWYFLENGQRSDSSEEDVDKGVSAASSYIAMCSLPGAISDLYQIGLYNQCLKIIRNCCHTVRIGETVVTKKSSGAKKKKAGGKSDETNVDGEMTVTTGAADPIIGPPRIAVDSAERYLHHLTTQLFAFLHSNTFSIDTPTLMSTLEVVEDIGRLDLDNRTAGRAIRANSVHEFRSLERFTDRYCAFVHSLVESKYKTRAEVAYGRLIRPRLALMPYPDESNKSSKISTERKRSGELHVNLILSRISRNPEARELKYIQTVTVMVYSQCPDLAEFRTNIATFIHKILEALPYTYTYDFVQFMNVLFKGRGAGVKSLSTELSSILISSFDFTAPDPGAIPNLDAEQNEEEDEEEEGEDEEEEEENEQDDVAVKEEEQSDKSDEENDGDNEENVSKKKEEKKKEKKAKEVKEVGRMDAMSVLYNIVYMACLDKAAAMRLHGANSLTKILQSQSHREAFQLFCATINAEMDEKFGAVGDNLSESLEDLNVSGKAPSSKTKKPTDLLLDEQQIIQKFNKLKLMNKGETRVEKDIVYMIVRRLSTDDKAPVKKAACSLLKSYLSYCDEASKFEVVLSILQMLCRDRMVSVRKTGADAFTELMLRDAILFKESLSSKWLHTLISMLNDTDNDVTEHARKLIMKVLTPLLENSSDLTWTLLDTIESVTNHRQYLMSTLKDAVREKLVKRTVMDSMKQHIISGSEKLDGAWMVFSQLCVQFEQNVDFAIETFSRVDLSRESNLVQYMIHVIENNIKKIDDDTKSDLVNTLQGTFRDYCLHPSHSRSIYHCLGKLMDGIGDRSLHGKEFSDFGETLLIKCFDTIVQSFEMFKDKDEWKRNSESQERLLCTALNVASEVFSYSPQLVPRHERLGKTLSLIVNSTENGSSDASTVNPDMPSVHHTRPPTQLSEVPSSQKSSKGGMMSHEGAMFSDKVRAVGVVTLANMILAHDRLLKLMPMLVKQLQYNTAHQIRSNIVLAIGDICSSYKTDRYAPMLAASLCDPSVIVRRHAINQIARLISFGIFRFNGEIMIRMMLASLDANEDVRNDAKLYISEVLQSEEPNFFPLNFVQYMIALTQARRLVGVGHDEDDRGQVDVAIGGGDPLARPSRIAIYTFMIDSLDDRSRFDVKMSICQRIFTPIVNGEYDFSDYNVQCLLDDALLIMASNEMQVKMDVGKNPNENAMDDPSPEVLEAATGFMQKVYLDHYMKTIVPSILSLREFLNQHRSPLQRKCLLAIRMICIEHKNDIDEILQDNRQLKDEMMFELQRVKQRTEEANRILDEYLKRVAEFKKQQKRLSKSPAPMELDAEPVQESAEAVEMGSPARRIEEDQENVEEEVEMRTPQKKNPDADVPRTPLNALRSTTEEKSTPNARLLSPKTIKKIRRSLGALIHTEMRLNPPNLEETKIDDTTINRSKQADKTEEKTIVEEEPMEEAAAEKTVTAENDHVDAEKTVIAVEIPPATEAEEDEVVDVQSESRRSRRRKTPNYDDEESVDADGKIWKKPKIVNKSPEKEVNISANVTLRRSRRGQSTEPPVVKENSNRKRKSVDEEEENVPTSSSGNTENDPLSRGVTPLIFDESKLGAGRHCSTPIRSREDADPSDVTFSLNLSAITEKEDLKNRSKKVKLITFTISSKRMKRKADQCHCINLPSKFVLFISTVCIIVRLSAVFSLN
What is the function of this protein?
Chromosomal protein which is recruited to mitotic chromosomes by hcp-3 (CENP-A) and hcp-4 (CENP-C) (PubMed:12080088, PubMed:15767665).  Involved in chromosome segregation during mitosis, playing a role in chromosome condensation and in maintaining chromosome morphology, rigidity and orientation during mitosis (PubMed:12080088, PubMed:15767665).
What are the official names of this protein?
Condensin-2 complex subunit hcp-6, Holocentric chromosome-binding protein hcp-6, Holocentric protein 6.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes to the centromere during mitosis (PubMed:12080088). Co-localizes with hcp-3 (CENP-A) at prophase, metaphase, and anaphase chromosomes (PubMed:12080088, PubMed:15767665). Mitotic chromosome localization is dependent on hcp-3 (CENP-A) and hcp-4 (CENP-C) (PubMed:12080088, PubMed:15767665). Localizes along two parallel lines on individual prophase chromosomes (PubMed:12080088). At metaphase, localizes at the poleward faces of the metaphase plate (PubMed:12080088). During anaphase, localizes with the separating groups of sister chromatids (PubMed:12080088).
Protein: GCY2_CAEEL
Sequence: MVSSILKFVILIHSTFHSTFAQNLPDTTVAPKTKRTIKIGIAAAQRTQTSSIGWSVCGGAVPMAIERLREFGYVKDFDFEFIVDYTECDQGSVVRAGIEFIKTHKVDVIIGPPCAQALRVMSFLAENYKKPVLGWGFVSDTDLSDVIRFPYLTTVIPNSLMLGYAASKMLTVYNWGRVAMLYYYSDIKYCSGVMNDVEATFNNPSTPNVNIVIKAEIYLNDNETTDIVFQSVKSRARIIFWCTQTAIEKRDYLIKIATHDMIGDEYVHIMLSMRNIAFGAQTSLGKPTFSQSGLTPIWESFTEGTDDFEKMVKQAATRMFVLDVNSEVADKKYLDYLQKNIMKAVQSPPMNCSTVECMTANTTIMGGYARQLFDVVYLYGVALTNTNSTDPAVYDDVDVIVPQFVTSFQGMTGKVVISPNLTRMPIFQLYGLNSDYEQVALAEFTYIDPIMNVTLSYKEEGGAVWYFYGNSRPLDIPICGFLGKFCPISFWEQYMILAIVSISVIVLMVIIMIIGCLCVISAKHAEQARTNAEWQVPFVNLMESEKQIRSNATSRRSLQSAPSISTGHSGVTTVSDFCENYTMMMYEKEMVLTAKYQYTHLTKADKERFVKMRKLDHENINRFIGLSIDSAHFIAVTKLCSRGSLQDILSRGNFSMDYFFMFCIIRDVAKGLEYLHKTFLRLHGNLRSATCLVNDSWQVKLAEYGMDNLVEEQTPPKKRLLWVAPEVLRGSLSVSQMEPSADIYSFAIIASEILTKKEAWDILDRKEDCEALIALVKDCWAEVPEDRPTAENICSQMKGLVSKQKTNLMDHVFNMLEEYTSTLEEEIEERTKELTLEKKKADILLSRMLPKQVAERLKAGQTVEPEGFDSVTVFFSDVVKFTILASKCSPFQTVNLLNDLYSNFDTIIEQHGVYKVESIGDGYLCVSGLPTRNGYAHIKQIVDMSLKFMEYCRSFKIPHLPRENVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGKPSLIHLTSDAHLLLLTHYPNHYDTSSRGEVIIKGKGVMETFWVHGRIDDIAEPTELRSICKPSTVANERWITPPAPKPEIRSVSSHGSRPPSVYDPLQDHRKFKMDTLKVAN
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-2.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PSBC_CUSOB
Sequence: MKTLYSLRRFSHVETLFNTTLAVAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFGPEKPMYEQGLILLPHLATLGWGVGPGGEIIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPEIIEESFPLFRYVWKDRNKMTTILGIHLILLGLGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSIIFGFLLKSPFGGDGWIVSVDDLEDIIGGHVWVGSICIVGGIWHILTKPFAWARRALVWSGEAYLSYSLGALSIFGFTACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGAAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLNRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFCLGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: TPIS_ECOLU
Sequence: MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHRF3_RAT
Sequence: MASTFNPRECKLSKKEGQNYGFFLRIEKDTDGHLVRVIEEGSPAEKAGLLDGDRVLRINGVFVDKEEHAQVVDLVRKSGNSVTLLVLDGDSYEKAVKHQVDLKELDQSPREPALNEKKPDLGMNGGVETCAQPRLCYLVKEGNSFGFSLKTIQGKKGVFLTDITPQGVAMKAGVLADDHLIEVNGENVENASHEEVVEKVTKSGSRIMFLLVDKETARCHSEQKTPFKRETASLKLLPHQPRVVVIKKGSNGYGFYLRAGPEQKGQIIKDIEPGSPAEAAGLKNNDLVVAVNGESVEALDHDGVVEMIRNGGDQTTLLVLDKEADRIYSLARFSPLLYCQSQELPNGSVKEAPAPISAPLEAPGSATTEDVGDHKPKLCRLIKEDDSYGFHLNAIRGQPGSFVKEVQQGGPADKAGLENEDIIIEVNGENVQDEPYDRVVERIKSSGEHVTLLVCGKVAYSYFQAKKIPILSSLADPLVAGPDAKGETEHDSAESTKDSSHPARDRTLSAASHSSSNSEDTVM
What is the function of this protein?
A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains.  May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades.  In complex with NHERF1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins.  May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1.  May potentiate the CFTR chloride channel activity (By similarity).  Required for normal cell-surface expression of SCARB1.  Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1.  Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney.  May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).  Component of a complex, composed of PDZK1, SYNGAP1, KLHL17 and NMDA receptors.  Interacts (via PDZ1 domain) directly with KLHL17; the interaction is important for integrity of actin cytoskeleton structures in neurons.
What are the official names of this protein?
Na(+)/H(+) exchange regulatory cofactor NHE-RF3, NHERF-3, C-terminal-linking and modulating protein, Dietary Pi-regulated RNA-1, Diphor-1, Na(+)/H(+) exchanger regulatory factor 3, Na/Pi cotransporter C-terminal-associated protein 1, NaPi-Cap1, PDZ domain-containing protein 1, Sodium-hydrogen exchanger regulatory factor 3.
What is the protein family that this protein belongs to?
Belongs to the NHER family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cell membrane. Note=Associated with peripheral membranes. Localizes to the apical compartment of proximal tubular cells and to sinusoidal liver membranes.