PharMolix/UniProtQA huggingface dataset:
Protein: SYS_DECAR
Sequence: MLDIQQLRSNLDAVAEGLAKRGKPIDFSEFSALEAERKTLQTRTQDLQAQRNSLSKQIGMLKGKGEDASEVMAQVGSIGDELKASEARLAELLTQFNAILAALPNIPDDSVPVGSDETGNVEIKRWGTPRVFDFEVKDHTDVGEALGQLDFGTAAKISGARFSLLKGGLARLHRALAQFMLDTHTAEHGYTELYAPYLVNAASLYGTGQLPKFEEDLFKVLRGDQDPLYLIPTAEVPVTNIVRDEILSAEALPLKFVCHTPCFRSEAGSGGRDVRGMIRQHQFDKVELVQVVHPEKSAEAHEELTRQAEIILEKLELPYRRMALCSGDMGFSAAKTYDLEVWLPAQNTYREISSCSNFGAFQARRMQARFRNDKNKTELCHTLNGSGLAVGRTLVAILENNQNADGSVTIPAVLRPYMGGLEVLSAA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_KOSOT
Sequence: MSRSKKKGPYVHPKLLKKIKEMNEKGEKKPIKTWSRASMVVPEMIGHTIAVYNGMKHIPVYITENMIGHRLGEFSPTRRFGGHADKKSKKGQVK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: FMT_AGRRK
Sequence: MSLSIIFMGTPEFSVPTLRSLIDAGHKIRAVYTQPPRPGGRRGLDLQKSPVHQAAELLGLPVFTPVNFKDQEERQRFRELDADVAVVVAYGLLLPEAILTGTRLGCYNGHASLLPRWRGAAPIQRAIMAGDKKTGMMVMKMDKGLDTGPVALTREVEIGGTMTAGELHDKLMQAGAKAMAEAMNKLEYNELPLTEQPAEGVVYAAKIDKGETRIDFSKPAADVHNHIRGLSPFPGAWFEMEIAGKPERVKVLGSELAEGERAVGEVLSDDLAIACGSGAVRLTKLQKAGGKPMAAADFLRGTPVAAGTILALGPV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: EFTS_SYNE7
Sequence: MAEISAKLVKELREKTGAGMMDCKKALNENDGDLQKAIEWLRQKGIASAEKKSGRTAAEGLVGSYIHTGGRVGVLVEVNCETDFVARGDKFQELVRSIAMQIAACPNVEFVKVEDIPAEIAEREKAIEMGRDDLANKPENIREKIVVGRIEKRLKELTLLDQPYIRDPNISVAELVKQSIAELGENIQVRRFTRFVLGEGIEKAESDFAAEVAAQAAAAQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_METCA
Sequence: MKTPVHVAVTGAAGQIAYSLLFRIAVGDLFGPHQPVILKLLDVPSAERVLEGVAMELDDCASPLLQEIEVSSDPAEVFDGAEAVFMLGATPRGPGMERRDLLQVNADIFSAQGRALNESASRRVKILVVGNPANTNALIAQRNAPDLAPGCFSAMTRLDHNRATSLLARHCGCNVAEISRVVIWGNHSPTQYPDLHHARVKGKPALSLVDPAWYVETFIPTVQQRGASVIAIRGKSSAASAANAALDHMRSWFLGTPKDDWVSMTVSSDGSYGIAEGLMFSFPVTIENGRFRIVQDLPLDTFSRERLRLTEVELLEERAMVSHLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: PROA_BACAN
Sequence: MNEVLAKGKKAKEIARELVLKSTEQKNEALSAIADQLILETAYILEENKKDIEEGKAKGFSDSLLDRLMLNEQRIVDMTEGIKQLIELRDPVGECVSAWERPNGLSIQEMRVPLGVVGMIYEARPNVTVDAATICLKTGNAVILRGSSSAIHSNKAIVAVIHRALKQTSLPQESVQLIEDTTRDSAKQLFTMNDYLDVLIPRGGKQLIDTVVREASVPVLETGAGNCHVFIDETADKQMAFDIINAKTQRPSVCNAIETIVLHEKWAEQYGSELFSSLKKRGVELRGDQKALAMDSTIVLASEEDWGTEFLSLTPAVKLVSSIEEAIHHINTYGSMHSEAIISENEEKVSKFFVSVDAAALYHNASTRFTDGSEFGSGAEIGISTQKLHVRGPMGLPALTSTKYVIRGNGQIRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_AZOC5
Sequence: MAFSASDVLVLIPARLAASRLPGKPLADVGGRPMIVEVARRAVAAGIGRVAVATDAVEIADAVRAAGFEAVMTRADHPSGSDRIFEALGVLDPDGAVQVVVNVQGDLPTIAPETIRAALVPLEEGPADIATLTAVITEEGERTDPNVVKVVGTPIGENRLRALYFTRATAPTGEGPLYHHIGLYAYRRAALERFVSLPPSPLEKRERLEQLRALEAGMRIDVAVVDAVPLGVDTPEHLERARALLASNDN
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_STRPN
Sequence: MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRDGVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVVDELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGLPVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_CHRVO
Sequence: MDKIVIASRESRLAMWQAEHIQARLQALYPHLTVEILGMTTQGDQILDKTLSKIGGKGLFVKELEQALMDGRADLAVHSLKDVPMTLPDGFALAAVCEREDPRDAFVSNRYQHLSELPAGSVVGTSSLRREAQLRARFPQLAVKPLRGNVQTRLKKLDDGEFDAIILAAAGLKRLGLAERIQGELAPSESLPAAGQGALGIEIRADRADLSALLAPLNHPDTRACTAAERALAKELGGSCQVPLGAFATLADGTLTLGGLVAHPDGSVVLTASASGPADYADALGRAVAKKLIDAGARPLIAAVLAEPR
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RECR_PEDPA
Sequence: MQYPEPIAKLIDSFMKLPGIGYKTATRLAFFTLDMEKDDVTEFAKALISAQRDLSFCSICGNITEDDPCDICQDPSRDQKAVLVVEDSKDVMSMEQMKEYHGLYHVLHGVLSPMDGKGPEDINIAALLTRLQKNEAIKEVIIATNATPEGEATAMYISRLVKPSGIKVTRLAHGLSVGSDIEYADQMTLYKAVEGRTEM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: TOP1_THEAC
Sequence: MDGFRIIIAEKADAGRRIAYFLSGGQVKSHRAKGTSYLEFEYNGSKTYLIPLSGHIVEADFESGYSDWNKIDLSDLIDARIVKNIKNKVAYQTLQAFRGKVEEIVIATDYDREGELIGVEALDIIKEGKEEIRRAKFSALTKNEILDSFKNLIGVNYSLADAADARESIDLIWGSVLTRFFSVTTGRLGKSFLSAGRVQTPTLAIVVDREREIQSFRPERYWTISITFDKDGQFKARYPENIKDQDTAEKIYEAIKGKNGRVSSYTSKEDHIRRPAPFSTTEFLREASRIGIMPTKAMSIAENLYMRGLISYPRTDNTVYPRSINLKSVLKKLENTAYSKYVKEIETFDRILPSRGRIETTDHPPIYPVDSPKEQLKGDYGRVYDLILRHFLSTLYRDGKKTVAEAEIYVNGYTFKAAGQHTTDRGWTEIYGYDPKDVYLPELTEGEDLKAIDWNIQREETKPPPRYDMSSLLKKMEELNLGTKSTRHDIIGKLIERGFIEGNPVKPTPLGMAFIDAVRSVNSHIADPEMTAKLEEDMDRIEKNEMSKNDVVEESKKMLHEVLSHFLTKTADVKDIITKGINAGQEIGDCPFHEGKKIMVIRDRFTYTVRCEDPSCKINFRIKRNGSITLSDQKCPVCGLPMIKIIRKGQSPEIKCIDPDCSYNRENEDYGECPADHGRLVLRQSKYGKRFLGCSNYPKCTVTYPLPQMGRITKTGEVCPYCGAPILALSRNGRKWKFCPNMQCEYNKKRKPEAAVEKSVRKKGRNASKS
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: SECA_BURP6
Sequence: MTTGFLQKIFGSRNQRLVKQYQKTVAAINALETQIETLTDDQLRGKTGEFRQRIAAGESLDKLLPEAFAVCREASRRVLKMRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLAAYLNALAGRGVHVVTVNDYLAQRDAEWMGRLYNFLGLSVGINLSGMEHDQKQAAYAADITYGTNNEFGFDYLRDNMVYETDSRVQRPLNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMNALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERMLAEWGLIGDGESLYAPQNITLMHHVYAALRAHTLFHRDQHYVVQNDEVIIVDEFTGRLMPGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTEAYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRECHERGQPVLVGTTSIENSELLSHLLKQAGLPHEVLNAKQHAREAAIVAEAGRPKRITIATNMAGRGTDIVLGGNVEKQAAFIEADESIPADEKARRIQQLHDEWETLHEQVKTAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLLRIFAGDRVRAIMDRLKMPEGEAIEAGIVTRSIESAQRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDIAETIGAMRHGVISEVVRQFVPAGSIEEQWDLPELEETLRNDWQLDLAIQEMVNESSSINADEILDAVTTAADEHYEAKVALVGRESFSAFERSIMLQTLDRLWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLDAVKQEVTRIVMNVQIQSPEQLEEAAEQIEEQGGQLGNVEFQHADFAAAAAAATAGGAVVADATAEMVGHAMSHSGPAGEVPRVGRNDPCPCGSGKKYKHCHGKLN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PRF3_ARATH
Sequence: MPLPHTHSLVVSTLSLEHSDKPQRRSRAKVKKKKKTNMSWQTYVDDHLMCDVAGNRLTAAAILGQDGSVWAQSNNFPQVKPEEIQGIKDDFTTPGTLAPTGLFLGGNKYMVIQGEPNAVIRGKKGAGGVTIKKTTLALVFGIYDEPMTPGQCNMVVENLGEYLIESGL
What is the function of this protein?
Binds to actin monomers and regulates the organization of the actin cytoskeleton (PubMed:23052593, PubMed:29861135).  Can increase the critical concentration (Cc) of actin assembly in vitro (PubMed:23052593).  Acts as downstream effector of the hydrogen sulfide signaling to regulate the assembly and depolymerization of F-actin (PubMed:25652660).  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (Probable).  Binding to the poly-proline motif of formin induces oligomerization of PRF3 (PubMed:29861135).  PRF3 oligomers inhibit formin-mediated actin assembly to modulate plant immunity triggered by pathogen-associated molecular patterns (PAMPs) (PubMed:29861135).
What are the official names of this protein?
Profilin-3, AtPRF3, AthPRF3.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HGPRT_MYCBO
Sequence: MHVTQSSSAITPGQTAELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGSSTSSSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_SHESA
Sequence: MSEKKINLLDLDRKAMRALFADLGEKPFRADQLMKWIYHFGVSDFEEMTNINKVLRQKLAARCEIVAPEISSYQKSTDGTIKFAIHVGEGQEVETVYIPEDDRATLCVSSQVGCALECTFCSTAQQGFNRNLTVSEIVGQIWRVSHFLGFAKETGERPITNVVMMGMGEPLLNLANVIPAMDIMLDDFGFSLSKRRVTLSTSGVVPALDKLGDALDVALAVSIHAPNDELRDILVPVNKKYPLQEFLAGIRRYIAKSNANRGRVTVEYVMLDHINDSTEQAHELAQLMKDTPCKVNLIPFNPYPGSPYGRSSNSRIDRFSKVLMEYGLTVIVRKTRGDDIDAACGQLAGDIRDRTKRLAKKRMQENQISVTMN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_CHLPD
Sequence: MIYQMQMPAKIEVDEATHTEMFGRFIAQPLERGYGVTIGNVMRRVLLASLPGTAITGVKIEGVYHEFSAIEGVREDVPEIVLNLKRVRFKSNCKRSCKTSLSIAGTKDFTAGDIIAKEGEFEVLNKDLHIATVNDGSVLNIEIYIGRGRGYLPAEENHPEGMPIGFIAIDAIFTPIRNVKFTVENTRVGQRTDYEKMILDVETDGSIAPDDSISLAGKIINDHIMYFANFSPTEEEFTEEEFKQQDDEFESMRKLLHTKIEDLDLSVRSHNCLRLAEIDTIGDLVSRKEDELLNYKNFGKKSLTELKEQLEKFDLKFGMDITRYQMK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: OPP28_HAEIF
Sequence: MKKTLAALIVGAFAASAANAAVVYNNEGTKVELGGRVSIIAEQSTSNRKDQKHQHGSLRNQGSRFNIKVTHNLGDGYYALGYYETRFINKDIDGNEKNIGSGFGSITTKLAYAGLGNKELGEATFGLQKTIADKISTAEDKEYGVIEKNSYIPTEGNAIAYTYKGIEGLTLGASYVFGGRNFSDYEITDGKVSNAVQVGAKYDANNIVAGFAYGRTNYKAQQAKTQQVNGALATLGYHFDDLGLLISLDSGYAKTKNKADKHEKRYFVSPGFQYELMEDTNLYGNLKYERINSVDQGEKVREHAVLFGIDHKLHKQVLTYIEGAYARTRTNDKGKTEKTEKEKSVGVGLRVYF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane protein P2, OMP P2.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: KDSB_XYLF2
Sequence: MSLEIVPFVVAIPARFSASRLPGKPLRLLGGRPLIHRVAERALSTGAREVWVATDDVRIAEAVASLDGVHVAMTANTHLSGSDRLAECARIAGWDPEVCVVNLQGDEPFAPAAGIRAVAALLHHSNADMATLATTIDKSEDLFNPNIVKLVCNTHGEALYFSRAPIPWNRDTFATTREPTPLGPWLRHIGLYACNAGFLQRFTTMQPGTLEQIESLEQLRVLEAGHRIAVRITPEHFPPGIDTPEDLAKAEKALEDV
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB_AILME
Sequence: MVHLTGEEKAAVTGLWSKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSTPDAVMNNPKVKAHGKKVLNSFSEGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PGLR2_JUNAS
Sequence: MSMKFMAALAFLALQLIVMAAGEDQSAQIMLDSDTKQYHRSSRNLRKRVHHARHDVAIVFNVEHYGAVGDGKHDSTDAFEKTWNAACNKLSAVFLVPANKKFVVNNLVFYGPCQPHFSFKVDGTIAAYPDPAKWKNSKIWMHFARLTDFNLMGTGVIDGQGNRWWSDQCKTINGRTVCNDKGRPTAIKIDFSKSVTVKELTLTNSPEFHLVFGECDGVKIQGIKIKAPRDSPNTDGIDIFASKRFEIEKCTIGTGDDCVAVGTGSSNITIKDLTCGPGHGMSIGSLGKGNSRSEVSFVHLDGAKFIDTQNGLRIKTWQGGSGLASHITYENVEMINAENPILINQFYCTSAAACKNQRSAVKIQDVTFKNIHGTSATTAAIQLMCSDSVPCSNIKLSNVFLKLTSGKVATCVNKNANGYYTNPLNPSCKSLHPGRTPKELELHQKPTTLLMDEKMGASLNSSPPNCKNKCKGCQPCKPKLIIVHPNQPEDYYPQRWVCSCHNKIYNP
What are the official names of this protein?
Polygalacturonase, PG, Major pollen allergen Jun a 2, Pectinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: PYRG_YERPA
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMTRRNNFTTGRIYSEVLRKERRGDYLGATIQVIPHITNAIKERIIEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVDVGREHTLYMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLTCPEANLAEWEQVLYEESNPGGEVTIGMIGKYVELPDAYKSVIEALKHGGLKNRLTVNIKLIDSQDVETRGEEMLKELDAILIPGGFGYRGVEGKVLAARYAREHNIPYLGICLGMQVALMEFARNVAGMENANSTEFVPDCKYPVVALITEWRDEDGNVEIRTEESDLGGTMRVGGQQCHLTEGSLVRQMYGEPTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSADNKLVEIIELPDHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAGDYQKRQVK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DNLJ_CHLTE
Sequence: MDKAKAQQEIGKLRAEIERHNRLYYLEAKPEISDFEFDKLLKRLIMLEKEFPELVTPDSPSQRVGGGITKEFPTVVHRDPMLSLSNTYSIAEVADFCNRVEKLVAAEGGGTPEYVAELKYDGVAISLLYRDGLLVCGSTRGDGRQGDEITANLRTIPSIPLRLEMPDLPLFGTALSGEIEVRGEVYMRKDDFERLNEERPEEERFANPRNATAGTLKLQDSAEVARRRMSFVAYYLKGYDGEAPTHLKRLEQLKSMGFMTGAAAKLCKGMDEIADFIAEWSEKRWTLPYETDGVVLKLNEVSLWERLGATAKSPRWAIAYKYPAQQAKTVLQGVVFQVGRLGTITPVAELKPTRLAGSIVSRSTLHNFDEIKRLGVRIGDHVMIEKSGEVIPKVVSVVLDERPAETAEIEVPSECPVCGTRLERPEGEVNWYCPNEEGCPAQKRGRILHFASRNALDIQNLGESLVTQLVDRGLVSDAGDLYSLTQEQLAGLDRMAAKSAQNVLDALEKSKKQSYARLLFALGIRHVGAATARELAHACPSIDRLREMDEEALAAVPDIGPVIAASIRDFFAKPWVQAMLQKLAEAGLPMQAGEEKALVNNNFEGQSVIFTGALERHVRQEAEEMVRERGGRIVSSVSKKTTLVVAGKEAGSKLEKAIKLGVKVIDEDEFERML
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: LAPA_SHIFL
Sequence: MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTLLAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVVPHSSAAKE
What is the function of this protein?
Involved in the assembly of lipopolysaccharide (LPS).
What are the official names of this protein?
Lipopolysaccharide assembly protein A.
What is the protein family that this protein belongs to?
Belongs to the LapA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RISB_THEON
Sequence: MEVRVFEGEFKGDGLSMAIVVARFNDLLTDELLSGAIDCFERHGVERVDVFKVPGSFEIPIIAKKLAESGKYDAILALGVVVRGETKHFDLVANEVSKGVAQAGLITGVPVIFGVIAVEDELQGLNRAGIKSNKGFEYAMAALEMANLMKKL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ISPG_CLOTE
Sequence: MDRKETIKIKVGDKFIGGDSPITVQSMTNTDTRDVEKTVEQIKKLEEVDCDIIRCAVPDDEACQALGKITKKIAIPLVADIHFDYRLAIKAIDNGISALRINPGNIGNEEKVNLVSKKAKEKGIPIRIGVNSGSLEKDILNKYGGVCSDALVESALRHVEILNKVDFHDIVISIKSSNVNQMIESYKKISSKVNYPLHLGVTEAGTPWRGIIKSSVGIGTLLSQGIGDTIRVSLTGDPIEEIKAGKEILRALNLYSKGVEFISCPTCGRTEINLIKIAKEVEKRLDGFDKNIKVAIMGCVVNGPGEARDADIGIAGGKGYGLIFKKGEVVRKLKEEDLVEGLIEEIKNI
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RNH_LEGPH
Sequence: MKVEIYTDGACKGNPGPGGWGVLLRYNGREKTLHGGEAQTTNNRMELMAAIKGLEALKRPCEVDLYTDSQYLQQGMKEWIKTWKRNGWRNSKKELVKNAELWKSLDNLASIHNIHWHWVKGHSGHLENDLVDALANLGIEELS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHF4_HUMAN
Sequence: MTPSRLPWLLSWVSATAWRAARSPLLCHSLRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTKEKGGPRGPEPTRYGDWERKGRCIDF
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954416).  Binds to the flavoprotein subunit SDHA in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit SDHB into the SDH catalytic dimer (By similarity).
What are the official names of this protein?
Succinate dehydrogenase assembly factor 4, mitochondrial, SDH assembly factor 4, SDHAF4.
What is the protein family that this protein belongs to?
Belongs to the SDHAF4 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.