PharMolix/UniProtQA huggingface dataset:
Protein: ASSY_NOVAD
Sequence: MSDIKKVVLAYSGGLDTSVILKWLQVTYNCEVVTFTADLGQGEELEPARAKAKLMGVPDHHIYIDDLREEFVRDFVFPMMRANARYEGDYLLGTSIARPLISKRLIEIARETGADAVAHGATGKGNDQVRFELSAYALEPGIKVIAPWREWDLTSRTALIAWAEAHQIPVPKDKRGESPFSTDANLLHTSSEGKVLEDPWQETPDYVYSRTVNPEDAPDTPEYITIDFEKGDGVALNGEAMSPATLLAALNDLGRKHGIGRLDLVENRFVGMKSRGMYETPGGEIYARAHRGIESITLDRGAAHLKDELMPKYAELIYNGFWFSPEREMLQAAIDHSQARVNGTVRLKLYKGSASVVGRKSPDSLYSERHVTFEDDAGAYDQKDAAGFIKLNALRLRLLAQQGR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMT2_CANGA
Sequence: MSELHSLLTFPVRPISEEHYLGELSRFLKAGIPATYTLEQVAAFERSELREDADEVSDEEEQSNTTPLHILARSLPGNLSDDEEQVVLHMMDMLFEYGAGWNFIDFENKTVGDLILERNGGNRESPLYQRVVEAGVSAELLLRKLNGGDVEFIDENEIDICAEASAEVVPKDALDDSTGKVSSVSDDDATAADPDTYLNTKLKYTEDALITENNKDGVMMDWETDIMKLAADTLVSRKPVGESVVLNIGFGMGIIDTFIQERNPKKHYICEAHPDVLKKMKNDGWYQKPNVVILEGKWQDSLNKLLDEGNVFFDGIYYDTFSEHYEDMLDLYDIVVGLVNPEGVFSFFNGLGADRPLCYDVYKKIVEVDVATYGMNCEYTYVDLKGKLPDWKDVKRSYYNCEYYYHPKISFA
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins.  Monomethylates ribosomal protein L12.
What are the official names of this protein?
Protein arginine N-methyltransferase 2, Protein-arginine N5-methyltransferase, Type IV protein arginine N-methyltransferase, Type IV PRMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GCST_SHESR
Sequence: MANKTVLFNKHLESNAKMVDFHGWDMPLNYGSQIEEHHAVRQDAGMFDVSHMTVVDVTGTDACAFLRKLLANDVAKLKVPGKALYGGMLDDNAGIIDDLITYYLTDTFYRVVVNSATREKDLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVFSSEQNAAIEGMKPFFGKQAGSLFIATTGYTGEVGYEIIVPETEAEALWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDMDETINPLAANMGWTIAWEPTDRDFIGRKALEALRDAGTDKLVGLVMEEKGVLRHDMPVFFTDAAGVEQQGVITSGTFSPTLGYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNGKQAF
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: DDR2_YEAST
Sequence: MKVSQVFISAISVFGLATSVNAQNASNTTSNAAPALHAQNGQLLNAGVVGAAVGGALAFLI
What is the function of this protein?
May play an important role in the response of cells to diverse environmental stresses.
What are the official names of this protein?
Protein DDR2.
What is the protein family that this protein belongs to?
To yeast HOR7.
Protein: SLD2_SCHPO
Sequence: MHDESRTKQISSIKALLKKWEHEYVHTNNCKPSKEDVKKQPEIALLYKQYYELKRESSITPKKAKTKVDFKFQTPTKQRAETEANESPKAPRNDYLQVTPKTVDKSLLGPTPQLSRRVLNLLEDMSPIADSHVDQISDIKHNTSEISSTMIPTTPSKNPEPVAQHTPTVLETPSSYRLQVYTSPNLLRVNAPCRKSLSEMLRELKDIEDDYGSNEEKILQEFESFSSSSSESLVDRDISQPMKKKIKRQNRLVKLPPSMNLSKSHLEGLPEIDEDAENGIDDNEDTTASKDSSPFLDLQSERQNKKIMRNGLVIGKQVSQNYSSYKLKKRKFRRHRS
What is the function of this protein?
Has a role in the initiation of DNA replication.  Required at S-phase checkpoint.
What are the official names of this protein?
DNA replication regulator sld2, DNA replication and checkpoint protein 1.
What is the protein family that this protein belongs to?
Belongs to the SLD2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ERPA_BUCAI
Sequence: MENAFKSHLQFTEKAIKKIKNLIEIEKNHDLKLRIYINGGGCSGFQYQFIFDTSINEDDIIITQSEVSLIIDPISLQYLYGGQIDYLENLEGSKFIVYNPNAKNTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: ATPD_BACC1
Sequence: MSNGIVAKRYAVALFKIAKEKHVLEMFEEELRLVQNVYVKNGELHSFLTQPNISKEQKKTFLANVFGSVSESILNTLYILIDNKRIDILPEIADEYVVLANEERNVADATVYSTRLLSEEEKLNIAEAFAKRTGKDAIRVKNVVDEDLLGGIKVRIGNRIYDGSLQGKLARIQRELMKNR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TTCA_SHIFL
Sequence: MSQNQEISKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGTTKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGDLAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREA_ORYSJ
Sequence: MKLVQREAEKLALHNAGFLAQKRLARGLRLNYTEAVALIAAQILEFVRDGDRTVTDLMDLGKQLLGRRQVLPAVPHLLETVQVEGTFMDGTKLITVHDPISSDDGNLELALHGSFLPVPSLEKFSSVGVDDFPGEVRFCSGHIVLNLHRRALTLKVVNKADRPIQIGSHYHFIEANPYLVFDRQRAYGMRLNIPAGTAVRFEPGDAKTVTLVSIGGRKVIRGGNGIADGAVNRSQLNEVMEKVIANGFGHEDYPDSSEGIIGDGTHDYSVDHEKYASMYGPTTGDKIRLGDTDLFAEIEKDYAIYGDECIFGGGKVLRDGMGQSAGYPASDCLDTVVTNAVVIDYTGIYKADIGINGGLIVAIGKAGNPDVMDMDGVNEEMIVGVNTEVIAAEGMIVTAGGIDCHVHFICPQLAEEAIASGITTLVGGGTGPAHGTCATTCTPSPSHMKLMLQSTDELPINMGFTGKGNTTKPDGLAEIIKAGAMGLKLHEDWGSTPAAIDNCLSVAEAFDIQVNIHTDTLNESGCVEHTIAAFKDRTIHTYHSEGAGGGHAPDIIKVCGVKNVLPSSTNPTRPFTLNTVDEHLDMLMVCHHLDRNIPEDVAFAESRIRAETIAAEDILHDMGAISIISSDSQAMGRIGEVITRTWQTANKMKRQRGRLPISSSPDAAEDNDNFRIRRYIAKYTINPAIVNGFSDFVGSVEVGKLADLVIWKPSFFGAKPEMVIKGGAIACANMGDPNASIPTPEPVMMRPMFGAFGGAGSANSIAFVSKAAKEAGVAVQYKLGKRVEAVGRVRGLTKLNMKLNDALPKIDVDPETYTVTADGEVLRCQPTPTVPLSRNYFLF
What is the function of this protein?
Urea hydrolase involved in nitrogen recycling from ureide, purine, and arginine catabolism.
What are the official names of this protein?
Urease, Urea amidohydrolase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
Protein: NHAP2_PSEPF
Sequence: MNATTINSLFLIGALLVGASILVSSLSSRLGIPILVIILAVGMSAGVDGGGIIFDNYPTAYLVGNLALAVILLDGGLRTRVSSFRVALWPALSLATVGVLITTGLTGMAAAWLFDLNLIQGLLIGAIVGSTDAAAVFSLLGGKGLNERVTASLEIESGSNDPMAVFLTVTLIDMLASGQTGLHWSLLTHLIREFGIGGVIGLGGGWLMLQLVNRINLATGLYPILVIAGGLVVFALTNALHGSGFLAVYLCGLVIGNRPVRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIALPALGLALWMILFARPLSVLVGLLPFKAFHGREKAFISWVGLRGAVPIILAVFPLMAGLPNAQLYFNLAFFIVLVSLLVQGTSLPWVAKLLKVTVPPEPAPISRAALEVHVTSEWELFVYKLGAEKWCIGSPLRELKMPEGTRIAALFRGQQLLHPSGSTVLEVDDLLCVIGHEHNLPALGKLFSQAPQRGLDLRFFGDFVLEGDAQLKAVAALYGLPAEGIDPDMTLGHFIAQKVGGAPIVGDQVEWNNTHWTVAVMDGNKIGKVGVRFPEGSRPGPGLFL
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSME2_PIG
Sequence: MAKPCGVRLSGEARKQVDVFRQNLFQEAEEFLYRFLPQKIIYLSQLLQEDSLNVTDLTSLRAPLDIPIPDPPPKDDEMETDKQEKKEVPKCGFLPGNEKILALLGLVKPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAVQEKVLERVNAVKTKVEAFQTTISKYFSERGDAVAKASKETHVMDYRALVHERDEAAHGELRAMVLDLRAFYAELYHIISSNLEKIVDPKGEEKPSMY
What is the function of this protein?
Implicated in immunoproteasome assembly and required for efficient antigen processing.  The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity).
What are the official names of this protein?
Proteasome activator complex subunit 2, Proteasome activator 28 subunit beta, PA28b, PA28beta.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
Protein: OTCC_STRE9
Sequence: MTNVFKGRHFLAEKDFTRAELEWLIDFSAHLKDLKKRNIPHRYLEGKNIALLFEKTSTRTRAAFTVASIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQKMVEELAEFSGVPVWNGLTDAWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEVVALAEGFAKESGARVLITDNADEAVKGADVLYTDVWVSMGEEDKFAERVALLKPYQVNMELVKKAENENLIFLHCLPAFHDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGDPFVPRV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_BACLD
Sequence: MEDLFLKALPLLRELKKHGWQAYFVGGAVRDAQMNRDVGDIDIATDASPEEIEAIFPKTVDVGKEHGTIIVLFEGESYEVTTFRAELEYEDYRRPSGVQFIKSLKEDLKRRDLTINAMAMDEEGRLIDYFGGLRDIRERLIQTVGDPAERFHEDALRMLRALRFMSQLEFELSPNTKKAICENRPLLAHISTERKTVEFEKLLKGKAAGRALEAAAETGLYKELPGLDGKKERVLAARAFPFYQLQKSADIWAAFIHMISINPAEAHRFLKGWKLPGKVIRQALHTAERIDQKWDAVSMYEAGEETLLAASAIRSLRDKQAIDEEQLAEIRQSYQALPIKSLKDLAVSGSDLLNFRKKPAGKWVSDDLKRIERAVLNGELANQKKAIEEWLDSCSQI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: VTU4_DROTE
Sequence: MKIVAFTLVAFVALAGASCPYAAPAAAYPAPVAPSGYPAPPCPTNYLFSCQPNLAPAPCAQEAPAYGSAGAYTEQVPHYVGNPSREQVQQFHQRIGMAALMEELRGLGQGIQGQQY
What is the function of this protein?
Major early eggshell protein.
What are the official names of this protein?
Vitelline membrane protein Vm32E.
What is the protein family that this protein belongs to?
Belongs to the vitelline membrane family.
What are the subcellular locations of this protein?
Secreted.
Protein: DTD_BACSU
Sequence: MDEEVVGQIGQGLMVLVGITHDDTEDDAAYLADKVVNLRIFDDSEGKMNLSLVDIGGEILSVSQFTLYGDTKKGRRPNYMNAAKPDKALGLYEKWNDLLREKGIKVETGTFGAMMDVQLTNSGPVTLIMDSK
What is the function of this protein?
A non-functional D-aminoacyl-tRNA deacylase (PubMed:4292198, PubMed:24097941, PubMed:25441601).
What are the official names of this protein?
Inactive D-aminoacyl-tRNA deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
Protein: YAII_ECOK1
Sequence: MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRFIRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATIRERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG
What are the official names of this protein?
UPF0178 protein YaiI.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: SERC_LEPIN
Sequence: MYLFQERIYNFGAGPAMLPNEVMEIAAAEFLNYKGSGMSVMEVSHREPLFEDVITEAEILLRKLLNLGEDYSIAFFSGGATLHFSALPLNLLKEGESFDVAHTGIWTKKAWEEGLKFNEVNVIYDSTNNHFTDVPVLTDSNLSGKGKYLHITSNNTIYGTQYPEIPKIKQIPLVADMTSELLSRKIDVKDFGVIFAGAQKNIGPSGLSLAIIRNDLLGISGRKIPILLDYSVMVKNRSLYNTPSTYSIYIAKLVFEWLLKLGGIEAIEKVNEQKAKLIYDFIDSSSLYVCPVQKRARSKMNVVFLLKDKNLDSKFLDEAEKNGLHGLGGHRLVGGFRASIYNSMPLTGVQKLVSFMKDFESKI
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_RICPR
Sequence: MKFTLSWLKQFLEISASVTEIAEALTDIGLEVEEVIDKSKELQKFEVAYIRNIKPHPSADKLKLCDVETKNGILQIVCGASNVRADIKVVLANIGIEIPKGNLKIKESVIRGQKSYGMLCSEEELLLSSNSDGIIELPKDAVVGDNFTKYYGLDDPIFVINVTPNRGDVLGVYGIARDLSAKGLGTLKELELSEIKSTFFSKIKLNVHDKEACPLFTFREIRNLKNKPSPNWLQQLLKNVGIKTISSLVDVTNYISHSFGQPIHAYDADKIYGGISVDCYIRSDKVISCKNHEMATAVLQFSNDSANFYAINGKGYLLTENDLAIKDESGIQGLAGIIGGAKSSCNDSTTNVILEAACFNAKMVAASGRRLKIDTDARYRNERNIDRNFTEKALNIATNLILSICGNCEVSEVVKVGEQEPQKKPLDFSVYFLEKITGIKLSIQEIEDILNKLGFITDVKGDIIKVIAPSWRHDINILEDIAEEIVRIYGYDKIESIKLPELYQNNNLREYKRISSFKRILASKGYDEVVTNSFMSSEDAKLFAELKEGLFLLNPMSIEENYMRPTVLPNLISIVSKNLARDVKDMAFFEVGPSFVNLNIESTYLTAIISGAFNNKNPHSFGRNYDIFDIKGDLEQVIEYAGLSLDKCIVIDETVLPQYYHPTRAINIRLGKNLLGHFGQIHPKILKYYDINQEIFAFELNITNLPLIKAKFGKRDEFTVSDYQANFRDYSFIVDQDHKVGEIISYIKNFNKKLVKSVMLFDIYSGDKLPEGKKSIAIKIKLQADDRTLSETDLNSFSEDLVASISQKFQGILRE
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_STAES
Sequence: MKIQTEVDELGFFGEYGGQYVPETLMPAIIELKKAYEDAKSDTHFKKEFNYYLSEYVGRETPLTFAESYTKLLGGAKIYLKREDLNHTGAHKINNAIGQALLAKRMGKTKLVAETGAGQHGVASATIAALFDMDLIVFMGSEDIKRQQLNVFRMELLGAKVVSVSDGQGTLSDAVNKALQYWVNHVEDTHYLLGSALGPDPFPTMVRDFQSVIGNEIKSQILSKEGRLPDALVACVGGGSNSIGTFYPFIQDDVKLYGVEAAGKGSHTHNHALAIGKGKPGVLHGSKMYLIQNDDGQIELAHSISAGLDYPGIGPEHSYYNDIGRVSYVSATDNEAMEALITFSKVEGIIPAIESAHALSYVEKLAPNMDEKEIIVVTISGRGDKDMETIKQYKENGGEQNE
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: UVRB_MYCGE
Sequence: MKNQTKSNSLFQLSTNYIPTGDQPEAIKKLSEFKTKQQVLLGATGTGKTFTIANVIQNSQLPTVVIAHNKTLAGQLFNELKQLFPKNAVEYFISYFDFYQPEAYLPSKGIYIEKSATVNEAIKRLRVSTLHSLSTRKDVIVVGSVASIYPTSSPSDFVKYCLWFVVGKDYDLKTIKDRLVSLNYVVNKQQLTPGKFRFQGDVLEVFPGYSDAFVIRISFFDTKVEQICQIDPLTNKILNQLFEIKIGPADEYVVNQSDLDIAIKNIKQELQERVNYFNKQNLVERAQRLATITNHDLNDLKAWGFCSGVENYARHLELRMANSTPYSIFDYFKGDWLLVIDESHQTLPQLNGMYNTDLSRKQSLIDYGFRLPSALDNRPLSFAELQQKMQKVIYVSATPRDKEISLSQNNVIEQLVRPTYLVDPIIVVKPKDNQVEDLIEEIINQRQNNTRTFVTVLTIKMAENLTEYLKERKIKVAYIHKDIKALERLLLINDLRRGEYECLVGINLLREGLDVPEVALVCIFDADIPGLPRDERSLIQIIGRAARNEHGRVVMYANHVTEQMQKAIDETKRRRTVQMEYNKLHNKTPKTVVKPLTFVQPIKLKAKSNAEKNAALIKQLTKEMKKAAANQNYELAIEIRDSIFELEKEIGSKIKV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAC_LYSSH
Sequence: MLGCSSLSIRTTDDKSLFARTMDFTMEPDSKVIIVPRNYGIRLLEKENVVINNSYAFVGMGSTDITSPVLYDGVNEKGLMGAMLYYATFATYADEPKKGTTGINPVYVISQVLGNCVTVDDVIEKLTSYTLLNEANIILGFAPPLHYTFTDASGESIVIEPDKTGITIHRKTIGVMTNSPGYEWHQTNLRAYIGVTPNPPQDIMMGDLDLTPFGQGAGGLGLPGDFTPSARFLRVAYWKKYTEKAKNETEGVTNLFHILSSVNIPKGVVLTNEGKTDYTIYTSAMCAQSKNYYFKLYDNSRISAVSLMAENLNSQDLITFEWDRKQDIKQLNQVNVMS
What is the function of this protein?
The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide.  All peptidase activity is lost on conversion to the mature peptidase.
What are the official names of this protein?
Penicillin acylase, Penicillin V amidase, PVA.
What is the protein family that this protein belongs to?
Belongs to the peptidase C59 family.
Protein: RS11_CHLTB
Sequence: MVKNQAQKRGVKRKQVKNIPSGVVHVKATFNNTIVTITDPAGNVISWASAGKVGYSGSRKSSAFAATVAAQDAAKAAMSSGLKEVEVGLKGTGAGRESAVRALISSGLIVSVIRDETPVPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: HLDD_ECO81
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLDIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: RR2_LOLPR
Sequence: MTRRYWNINLKEMVEAGVHFGHGIKKWNPKMAPYISAKRKGTHIINLARTARFLSEACDLVFDAASQGKSFLIVGTKKRATDLVASAAIRARCHYVNKKWFSGMLTNWSITKTRLSQFRDLRAEEKMGKFQHLPKRDVAILKRKLSTLQRYLGGIKYMTRLPDIVIVLDQQKEYIALRECAILGIPTISLVDTNCDPDLANISIPANDDTMTSIRLILNKLVFAICEGHSLYIRNH
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PTER_DROWI
Sequence: MSTVQTVLGAITPNLLGRTLTHEHVALDFEHFFRPPPADFERELQAKISMSTLGYVRMYPYSSKENVRFYDEEALEAAKKDVLLYKKHGGGSIVENSSYGLKRNLEFIVDLAKSTGVHFIAGTGHYIHAVQDASHASLTVEQMSDLYSKDIITGIQVNGETVKCGFIGEVASVYPVHEFEKHSLQAAGEIQEVLGCGVSLHPHRVTNAPFEIMRLYMEAGGRANKCVMSHLDRTIFDIDELLEFAKLGCYMQYDLFGTECSYYQLNSTINMLSDGQRIDNLMKLIEEGLVDRLLMSHDIHTKHRLTSYGGHGYHHIHMNILPRMFAKGVTIEQVEQMTVTNPANWLAFNP
What are the official names of this protein?
Phosphotriesterase-related protein, Parathion hydrolase-related protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
Protein: CMPDT_STUST
Sequence: MSEADQLKALRVRIDSLDERILDLISERARCAQEVARVKTASWPKAEEAVFYRPEREAWVLKHIMELNKGPLDNEEMARLFREIMSSCLALEQPLRVAYLGPEGTFSQAAALKHFGHSVISKPMAAIDEVFREVVAGAVNFGVVPVENSTEGAVNHTLDSFLEHDIVICGEVELRIHHHLLVGETTKTDRITRIYSHAQSLAQCRKWLDAHYPNVERVAVSSNADAAKRVKSEWNSAAIAGDMAAQLYGLSKLAEKIEDRPVNSTRFLIIGSQEVPPTGDDKTSIIVSMRNKPGALHELLMPFHSNGIDLTRIETRPSRSGKWTYVFFIDCMGHHQDPLIKNVLEKIGHEAVALKVLGSYPKAVL
What is the function of this protein?
Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
What are the official names of this protein?
Bifunctional chorismate mutase/prephenate dehydratase, Chorismate mutase-prephenate dehydratase, P-protein.
Protein: RSGA1_BACTN
Sequence: MSNENNNLSLYGWSDNLFRQKQISQYKDMSHGRIIVTHKTCYEVVAEDGVYLCELTGNMIYGRVPDEYPCTGDWVIFQPFDANKGIIVDILPRERALYRKKNGRVADRQAIASYVDKAFIVQSLDDNFNVRRAERFIAQVMEEKIKPVLVLNKADLGCDRQKIDEAIKHIARQFPVFITSIRQPQTILRLRESITKGETVVFVGSSGVGKSSLVNALCGKSVLNTSDISLSTGKGRHTSTRREMVLMDGSGVLIDTPGVREFGLAIDNPDSLTEMFEISDYAESCRFSDCKHIDEPGCAVLEAVHNGTLDHKVYESYLKLRREAWHFSASEHEKRKKEKSFTKLVEEVKKRKANF
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_YERPY
Sequence: MAKELNPTENIEKLSDIQRYVTQERGTEAPFTGKLLHNKRDGVYQCLCCHQPLFISESKFDSGCGWPSFYQPIDADSIRYIDDYSHNMHRIEIRCGNCDAHLGHVFPDGPQPTGERYCINSASLNFVDDQNGEQTAG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: WDR75_MOUSE
Sequence: MVEEGVRVVRCGGSRLNFRRAVFSVDSKYIFCVSGDFVKVYSTTTEECVHILHGHTDLVSGILVNPSNHLQLYSCSFDGTIKLWDYVDGILIKTFTIGPKLHAFFIPLHAEDSVFLTISKEEPDIFQLVSVKLPKSTSQDVEARQLTFVLDYINRSPKCIAFGNEGEYVAAVRDFYLSVYFFKKKKTCNFTLPSTKNKKNAKNKFTCVACHPKEDCIASGHMDGKIRLWRNFHSDQKYTYTCLHWHHDMVMDLAFTVTGTSLLSGGRECVLVEWRDGSEKNKEFLPRLGSSIEHISVSPAGDLFCTSHSDNKITVIHRNLDASAVIQGLVKDRSISTGLMVDPRTKALVLNGKPGHLQFYSLQGDKQLYNLDIIQQEYINDEGLTQTELTKAAFGCSGTWLATVEQRQENENELELQMKLWNYSKKTQGFVLNTKIAMPHDDHITALCFNNAESYEKPILVTASRDGHFKVWILTDDSDIYKKAIAWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDSQTWELKCTFCQRAGKIRHLCFGRLTCSKYLLGTTDNGILCCWNLLSCSIQWSAKLNVRVMEPDPYSDHVAAVAQSSAGSDLFVFKPSEPRPLYIQKNVSREEVQWGVFVPRDVPESFTSETHQWLNRSQFYFLTKSQSLLTFSTKSPEEKLTPTSKQLLAEESLPTTPFSFILGKHRQQQGAKLTETSENELVQLPLTENIPAITELLHTPAHVLPSASFLCSLFVNSLLLSKETKSAEEVPDDVDMEGNKESDDSDEEYDLTEKDKETNNNTDLGEDAIHQLSKSEEKELRKFRKVDYSWLTAL
What is the function of this protein?
Ribosome biogenesis factor.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.
What are the official names of this protein?
WD repeat-containing protein 75, U3 small nucleolar RNA-associated protein 17 homolog.
What are the subcellular locations of this protein?
Nucleus, nucleolus.