PharMolix/UniProtQA huggingface dataset:
Protein: LCRD_YERPE
Sequence: MNPHDLEWLNRIGERKDIMLAVLLLAVVFMMVLPLPPLVLDILIAVNMTISVVLLMIAIYINSPLQFSAFPAVLLVTTLFRLALSVSTTRMILLQADAGQIVYTFGNFVVGGNLIVGIVIFLIITIVQFLVITKGSERVAEVSARFSLDAMPGKQMSIDGDMRAGVIDVNEARERRATIEKESQMFGSMDGAMKFVKGDAIAGLIIIFVNILGGVTIGVTQKGLAAAEALQLYSILTVGDGMVSQVPALLIAITAGIIVTRVSSEDSSDLGSDIGKQVVAQPKAMLIGGVLLLLFGLIPGFPTVTFLILALLVGCGGYMLSRKQSRNDEANQDLQSILTSGSGAPAARTKAKTSGANKGRLGEQEAFAMTVPLLIDVDSSQQEALEAIALNDELVRVRRALYLDLGVPFPGIHLRFNEGMGEGEYIISLQEVPVARGELKAGYLLVRESVSQLELLGIPYEKGEHLLPDQEAFWVSVEYEERLEKSQLEFFSHSQVLTWHLSHVLREYAEDFIGIQETRYLLEQMEGGYGELIKEVQRIVPLQRMTEILQRLVGEDISIRNMRSILEAMVEWGQKEKDVVQLTEYIRSSLKRYICYKYANGNNILPAYLFDQEVEEKIRSGVRQTSAGSYLALEPAVTESLLEQVRKTIGDLSQIQSKPVLIVSMDIRRYVRKLIESEYYGLPVLSYQELTQQINIQPLGRICL
What is the function of this protein?
Could be involved in the secretion of the yop virulence proteins.
What are the official names of this protein?
Low calcium response locus protein D.
What is the protein family that this protein belongs to?
Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UVRB_RICAH
Sequence: MNHFSLISEYKPAGDQPKAIDEIIAGLNSKKRSQMLLGITGSGKTFTMANIIERTNRPTLIMAHNKTLAAQIYSEMKSIFPKNAVEYFVSYYDYYQPEAYIARTDTFIEKDSSINEHIDLMRHSATRSLLERRDVIVVASVSCIYGLGSPDLYYQMTVNLEPGKSYPRDKLLNDLINLQYKRNDMGFERGCFRVKGDNIDIFPSHYSDKAWRLSFFSNELEYIHEFDPLTGEKLAKLDKAIVFGHSHFVMPQDTVNNAISGIEEELQKRLEFLKSQNKLLETQRLNQRTQYDLEMLTETGSCKGVENYSRFFTGRNAGEPPPTLFEYLPKDALLFVDESHVSVPQIKAMYNSDRARKEVLVEHGFRLPSALDNRPLKFEEWEKFRPQTVFVSATPGPFELEETGGTVVELIIRPTGLLDPECIIKPATKQVEDLISEIQATVAKGLRVLVTTLTKKMAEDLTAYLQELKYKTSYLHSNVHTLERIEILQDLRQGTIDILVGINLLREGLDIPECGLVAILDADKEGFLRSEVSLIQTIGRAARNSEGRVILYADKMTKSIDKALSETLRRRQIQQEYNEKHGIIPKTINRAIHALATLERVDSKCDTKQAHTLFDNTAKLKANINKLNKEMLKAASNLEFEQAAKLRDQLKTLEAAARELS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LY6H_MACFA
Sequence: MLPAAMKGLGLALLAVLLCSAPAHGLWCQDCTLTTNSSHCTPKQCQPSDTVCASVRITDPSSSRKDHSVNKMCASSCDFVKRHFFSDYLMGFINSGILKVDVDCYEKDLCNGVAGAGHSPWALAGGLLLSLGPALLWAGP
What is the function of this protein?
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity.  In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response.  May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface.  Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons (By similarity).
What are the official names of this protein?
Lymphocyte antigen 6H, Ly-6H.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: RS20_BACAC
Sequence: MANIKSAIKRAKLSEERRAHNASIKSDMRSAVKTVEALVTNNDLENAKEAFKTASKKLDKAARKGLIHQNAAARQKSRLAKQVNA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: METE_SACD2
Sequence: MTTVHNLGFPRIGAKRELKFACEAYWRGEIDQTQLDKTAHTLRANHWQTQLDAGVEWLPVGDFSYYDHVLDTSFLVGNIPVRAQADGQSKLDTYFKVARGTAKEAAGASCCGGSHAAEMTKWFDTNYHYLVPELNANTHFKLNASKLLTELEQARALTSKVKPVILGPLSYLWLAKITDGSTHKLGFLDDLITVYRELLGTLAKEAVEWVQFDEPILALDLPEQWQHAFERVYHQLQLPNLSVLLATYFGPLDTNLRLAARLPTAALHLDITRGGDDLPRVLDILSPHKILSVGVIDGRNIWKADLNKLLAQLKPVKERLGNGLWLAPSCSLLHTPVDLDSEEALDADIKNWLAFAKQKLQELNILQRALDNGETSVAEALVHNAGAIAARKASAKVNNAKVQSLVNNISPSLSERESPFATRIEKQQAKYNLPTLPTTTIGSFPQTSEIRKNRKAFKSGEISQQQYDRTLRAEIAHAIELQEKIGIDVLVHGEAERNDMVEYFGEQLDGYVFTQFGWVQSYGSRCVKPPIIFGDVSRPRKITVDWAEYAQSLTSKPVKGMLTGPITMLQWSFVRDDQPRKITAQQIALALRSEVNDLEAAGITIIQVDEPALREGLPLRKKDWQNYLDWAVEAFKISTAGVGDTTQIHTHMCYAEFNDIIQAIADLDADVITIETSRSNMELLSAFEQFNYPNDIGPGVYDIHSPNIPATEQVVGLIKKAAENLPLQRLWINPDCGLKTRKWEDVIPALENMVNAAKQLRAEVA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: PYRB_SULIA
Sequence: MRLRHVVSSLDLTRDDYFRIFELVDKFSNVKKLNYLSGKVVSLAFFEPSTRTAQSFHTAAIKLGADVIGFASEESTSIAKGENLADTIRMLNNYSNCIVMRHKFDGAALFASEISDIPIINAGDGKHEHPTQALIDLYTIYKVFGEIDGRTFGLLGDLKYARTVNSLLRALTRFKPKKVFLISPSQLKVRREILDGLNYPVIETENPYDVIQDIDVLYVTRIQKERFVDEVEYEKVKESYVVDLKLVNMMKKDGIILHPLPRVTEIDRKVDKTTNAKYFYQASLAVPVRMALFYEVLGERKDD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TATA_METPP
Sequence: MGSFSIWHWLIVLLIVVLVFGTKKLKNIGSDLGGAVKGFKDGVRDGSTAPADPAQQVTANKSADANTVDVEAKQKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DTX6_ARATH
Sequence: MEDPLLLGDNQIITGSLKPTPTWRMNFTAELKNLSRMALPMATVTVAQYLLPVISVMVAGHRSELQLSGVALATSFTNVSGFSVMFGLAGALETLCGQAYGAKQYAKIGTYTFSAIVSNVPIVVLISILWFYMDKLFVSLGQDPDISKVAGSYAVCLIPALLAQAVQQPLTRFLQTQGLVLPLLYCAITTLLFHIPVCLILVYAFGLGSNGAALAIGLSYWFNVLILALYVRFSSSCEKTRGFVSDDFVLSVKQFFQYGIPSAAMTTIEWSLFEFLILSSGLLPNPKLETSVLSICLTTSSLHYVIPMGIGAAGSIRVSNELGAGNPEVARLAVFAGIFLWFLEATICSTLLFICRDIFGYAFSNSKEVVDYVTELSPLLCISFLVDGFSAVLGGVARGSGWQHIGAWANVVAYYLLGAPVGLFLGFWCHMNGKGLWIGVVVGSTAQGIILAIVTACMSWNEQAAKARQRIVVRTSSFGNGLA
What are the official names of this protein?
Protein DETOXIFICATION 6, AtDTX6, Multidrug and toxic compound extrusion protein 6, MATE protein 6.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GREA_BRUSI
Sequence: MEKFPMTPRGFEKLKEELRWRQQSERPRIIEAIAEARAHGDLSENAEYHAAKEAQSLNEGRINELEDLVARAEVIDVSKLTGDRIKFGATVTMIDEDTEEEKIYQIVGDQEADVKEGRISISSPIARALIGKGEGDTIEVNAPGGSRSYEIIALKFV
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ZNT7_MOUSE
Sequence: MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLVGIFVFNHGGHGHSHGSGHGHSHSLFNGALDHSHGHEDHCHSHEAKHGAAHSHDHDHAHGHGHLHSHDGPSFKATAGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPSLENTLPQCYQRVQQLQGVYNLQEQHFWTLCSDVYVGTLKLVVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM
What is the function of this protein?
Zinc ion transporter mediating zinc entry from the cytosol into the lumen of organelles along the secretory pathway (PubMed:12446736, PubMed:17954933).  By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases (By similarity).
What are the official names of this protein?
Zinc transporter 7, Solute carrier family 30 member 7, Znt-like transporter 2.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Protein: HRCA_THESQ
Sequence: MRRLNRKNNEALKKLNDRQRKVLYCIVREYIENKKPVSSQRVLEVSNIEFSSATIRNDMKKLEYLGYIYQPHTSAGRIPTDKGLRFYYEEMLKISKETSEADLAVETFKSVPLADPEKILFLAGNLLARLTQGYVLIERPNTRDLKILRVMLIPVSEDYLIFSILTEFGVSRVTPIKTQERLNWEEIERQLNFLLRGRTIGEVLMGKIESLKGSGFLRLIESLIGETVERYLDAGLENLLKDETLTLEDIRNLLEEVKDQKFLESLVGEGITVRIGREIGRKNLEKFAVFSGRYFKGESPIGSVYFFTSKVTRYDRNHKIFEYILNRLSEYFTSTSRR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: ATP25_CANAL
Sequence: MIVRGKCLGRSVSKAVSLFSRPISVISAKSFATTTNLLQNSKDDSTEATIPWYMREENSSPVEVLNKIEVPELPENSPQSLQEFVTLLTVEYGLTDLEIFDLSQLPEDHPKSLEEQNEENYVILASGKSEKHIYKAAYELRLYIKHTYKHLPIIEGMSSNSISKVTRRRLAKRVRRGPPATASTFGIGANSWVSCGTGVDGIVIHLLSRERRESLNLEQLYSDEQENEESHSTPEIDQDRLFFGDRRGFHTSSRNFNLNTLSNIYDSYVIDGNFDTSQKFKAQFDLNFKGGSVEEYNKKFELYRAINLVNANVVEANEIEQIIWDKYSSLDLALQQEIDWNTEIIKDTIKYMEFLVDLNARHSPREKLDKLSGFISNITCFAGDSIDLFTIDKFGALLWRLTWVSENNNALDSANLNEIIKRKGDFEPGTNTISFDNELGRNIRELLRQNKYSSNKETFPLWLREQMMYTFGQAGLWDRFWRDWQSILQSLNKTNERIYFWVVTALFLSKVDNRDALRHLFTKYWSNPSGASFVADYTTNNHQFNSDNERMALKSVLVQIGEKYNTSPWAREAAQFADNL
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: G6PI_PIG
Sequence: MAALTQNPQFKKLQTWYHEHRSDLNLRRLFEGDKDRFNHFSLNLNTNHGRILLDYSKNLVTEAVMQMLVDLAKSRGVEAARERMFNGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMPEVNRVLEKMKSFCKRVRSGEWKGYSGKSITDVINIGIGGSDLGPLMVTEALKPYSAEGPRVWFVSNIDGTHIAKTLATLNPESSLFIIASKTFTTQETITNAETAKEWFLQSAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINFFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAGKSPEDFEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSPVTSHDSSTNGLINFIKQEREARSQ
What is the function of this protein?
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity).  Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility.  Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons.  It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity).
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Autocrine motility factor, AMF, Neuroleukin, NLK, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted.
Protein: PSD_BURM1
Sequence: MNYPHPIIAREGWPFIAIAAVIALLIHAVGGFGFAWPFWLLLVFVVQFFRDPQRPIPAQPNAVLCPADGRIVAVETAHDPYANREALKISVFMNVFNVHSQRSPVDGAITKVEYFPGAFLNAAIDKASTENERNAVVIQTASGKTVTSVQIAGLIARRILCYVRAGEPLSRGQRYGFIRFGSRVDVYLPLGSRAKVSIGEKVYASSTILAELEQ
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RPO10_PYRHO
Sequence: MIIPVRCFTCGKVIGDKYYEFKRRVEAGEDPEKVLDDLGLERYCCRRMLLSHVELIDDIMHYKVY
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_STRA3
Sequence: MNTNDFDFYLPEELIAQTPLEKRDASKLLVIDHKNKTMTDSHFDHILDELKPGDALVMNNTRVLPARLYGEKPDTHGHIELLLLKNTEGDQWEVLAKPAKRLRVGTKVSFGDGRLIATVTKELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLEDRDRYQTVYAKENGSAAAPTAGLHFTKELLEKIETKGVKLVYLTLHVGLGTFRPVSVDNLDEHEMHSEFYQLSKEAADTLNAVKESGGRIVAVGTTSIRTLETIGSKFNGELKADSGWTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYNHAVEERYRFFSFGDAMFVK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM14_DROME
Sequence: MASSVILAGLSVAAVGFAGKHLMRRMPQMTTKFNEALKNLPKYDAESMAASKYYKGGFDPKMNKREASLILGVSPSASKIKIKDAHKKIMLLNHPDRGGSPYLAAKINEAKDFLDKAK
What is the function of this protein?
Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM14.
What is the protein family that this protein belongs to?
Belongs to the TIM14 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RNZ_STRPM
Sequence: MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQRQILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYVLTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCMGYRVVQKDLEGTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTRKTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVSARFLGRDCRQMEKDAATIFENVKMVQDLEEVII
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: CT5A_CONLT
Sequence: MLCLPVFIILLLLASPAAPKSLETRIQNDLIRAGLTDADLKTEKGFLSGLLNVAGSVCCKVDTSCCSSQ
What are the official names of this protein?
Conotoxin Lt5.10, Lt5j.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYE_XYLFT
Sequence: MTCRTRFAPSPTGYLHIGGARTALYCWLEARRRNGQFLLRIEDTDRERSTQAAIDAILHAMDWLGLDYDEPPVYQTQRIERYNQVAARLLAEGKAYYAYDSKDTLNAMREAALRTGEKPRYNGAAREANLPYRDDPNRVIRFKNPHTGTVAFDDLIKGRIQISNSELDDMVILRPDGYPTYNFAVVVDDWDMNITEVIRGDDHINNTPRQINLYHALGAPLPTFAHLPMILDEQGAKLSKRTGAADVMQYRDSGYLPHALINYLVRLGWSHGDQELFNRQALIDLFQINDVNSKAARLDMAKLGWVNQHYLKTDDPATLAPPLVWHLEQRGIDVSAGPAPTDVILALRERVQTLKEMAEKAEIWYCPLQRYDEIAVAKHLKPGAETALLHARTLLAALPAWTVDNVDTALRTTATTLEIGMGKVAQPLRVAITGTQVSPDIAYTVYLTGRNEALKRIDAALIKISTA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS3X_FIPV
Sequence: MLSLVSPLLKKSIVIQLFSITVYKFKAKFWYKLPFETRLCIIKHTRPKALSVTKQVKRDYRKIAILNSMRK
What are the official names of this protein?
Non-structural protein 3x, ns3x, Accessory protein 3x, ns3b.
Protein: MIAA_SALPB
Sequence: MNDVSKASLPKAIFLMGPTASGKTALAIELRKVLPVELISVDSALIYRGMDIGTAKPNADELKAAPHRLLDIRDPSQAYSAADFRRDALAQMAEITSAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRSRIEQQAAELGWEALHQQLQEIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIELRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYIEGEISYDEMVYRGVCATRQLAKRQMTWLRGWEGVRWLDSENPDRARKEVLQVVGAIAD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: OPGH_SHIFL
Sequence: MNKTTEYIDAMPIAASEKAALPKTDIRAVHQALDAEHRTWAREDDSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMFPDPWRTNPVGRFWDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTILPYQGWALINPMDMVGQDLWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQLLIGRDKYSISASTVGDEPLNPEHRTALIMPICNEDVNRVFAGLRATWESVKATGNAKHFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDDFCRRWGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDFVEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPELAIALFASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLFHTVFVVSAFLGWEVVWNSPQRDDDSTSWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLFWLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVDTDRFLEMNRQRSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRRLVLLSDPVTMARLHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROQ_ACIB5
Sequence: MSSTILVIHGPNLNLLGKREPEVYGHLTLDNINQQLIAQAEQASITLDTFQSNWEGAIVDRIHQAQTEGVKLIIINPAALTHTSVALRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAIGVICGLGAKGYSFALDYAIEKIQPSNPN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: IPDB_MYCTO
Sequence: MSTRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTPALGKTGAPNRIEGWMPFGRVFETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMFGVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDKVDPDNPAFRFVNVYRVVSNLGVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDPKSLRDREIRS
What is the function of this protein?
Involved in the final steps of cholesterol and steroid degradation.  Opens the last steroid ring of cholesterol by catalyzing the hydrolysis of (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA (COCHEA-CoA) to 6-methyl-3,7-dioxodecanedioyl-CoA (MeDODA-CoA).
What are the official names of this protein?
Cholesterol ring-cleaving hydrolase IpdB subunit, (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase beta subunit, COCHEA-CoA hydrolase beta subunit.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit B family.
Protein: ARNC_SALHS
Sequence: MFDAAPIKKVSVVIPVYNEQESLPELIRRTTTACESLGKAWEILLIDDGSSDSSAELMVKASQEADSHIISILLNRNYGQHAAIMAGFSHVSGDLIITLDADLQNPPEEIPRLVAKADEGFDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYGCMLRAYRRPIIDTMLRCHERSTFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSLLGSVIAIGGFSLSVLLIVLRLALGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQQVIYPESTPFTEESHQ
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FBX5A_XENLA
Sequence: MMCGFASNQSPKKLSSKKSSATNVHLEISPVKHHPPCKVYENVQGSCLDSAICTTVAKCADLTDDLPVHNKENLLHRLNDLETNSYEEYSALQDSGYSSILQNDSPCQDETDRKVSDIQVRETPKNFMSYQRPFHTLSKINLPILRFEEAVCSTLKKMRKTNKKIDWNAVDVVCGGNYGLEHLIGKSMGLERFDILAELFHRDFKHLLTKILRHLSAMDLINVISVSTTWRKLLQKDNWAYNAYKLGCKELCEKRAKVSSHTATRDESLCRVPLASVQKVAASSLCTSKKQSKNKNGGLSCNRLAEFIEVAQTLKNDQSLKVCVDCGSPAKHDPCLHRAICTRESCKLDFCTRCSCKYHFSKSCLMSKPGSYRIPSEPLPGSKKSKQNLRRL
What is the function of this protein?
Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC) (PubMed:15314241).  Binds to the APC activator cdc20 to prevent APC activation (PubMed:11389834).  Can also bind directly to the APC to inhibit substrate-binding (PubMed:11751633).  Required to arrest unfertilized eggs at metaphase of meiosis II, by preventing their release from metaphase of meiosis II, through inhibition of APC-dependent cyclin B destruction leading to stabilization of cyclin B-cdk1 complex activity (PubMed:11976684).
What are the official names of this protein?
F-box only protein 5-A, Early mitotic inhibitor 1-A.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In interphase, localizes in a punctate manner in the nucleus and cytoplasm with some perinuclear concentration (PubMed:11389834, PubMed:17159919). In mitotic cells, localizes throughout the cell, particularly at the spindle (PubMed:11389834). At metaphase, localized at mitotic centrosomes. Decreases centrosome localization as cells progressed through telophase (PubMed:17159919).