PharMolix/UniProtQA huggingface dataset:
Protein: EFTU_BACAC
Sequence: MAKAKFERSKPHVNIGTIGHVDHGKTTLTAAITTVLAKAGGAEARGYDQIDAAPEERERGITISTAHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLSEYGFPGDDIPVIKGSALKALQGEADWEAKIIELMAEVDAYIPTPERETDKPFLMPVEDVFSITGRGTVATGRVERGIVKVGDVVEIIGLAEENASTTVTGVEMFRKLLDQAQAGDNIGALLRGVAREDIQRGQVLAKSGSVKAHAKFKAEVFVLSKEEGGRHTPFFANYRPQFYFRTTDVTGIIQLPEGTEMVMPGDNIEMTIELIAPIAIEEGTKFSIREGGRTVGYGVVATIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_ECO81
Sequence: MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_STAAM
Sequence: MDNDRQKALDTVIKNMEKSFGKGAVMKLGDNIGRRVSTTSTGSVTLDNALGVGGYPKGRIIEIYGPESSGKTTVALHAIAEVQSNGGVAAFIDAEHALDPEYAQALGVDIDNLYLSQPDHGEQGLEIAEAFVRSGAVDIVVVDSVAALTPKAEIEGEMGDTHVGLQARLMSQALRKLSGAISKSNTTAIFINQIREKVGVMFGNPETTPGGRALKFYSSVRLEVRRAEQLKQGQEIVGNRTKIKVVKNKVAPPFRVAEVDIMYGQGISKEGELIDLGVENDIVDKSGAWYSYNGERMGQGKENVKMYLKENPQIKEEIDRKLREKLGISDGDVEETEDAPKSLFDEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYS4_NEUCR
Sequence: MIHPVRRALAVAASRAPRQFLAAASRTTSVRSVRAAAASGSYYSTTSRRLQDAFPSQLENLASSTLPKVVPQVPQTLTEKIVQRYSVGLAPGKKVKSGDYVTLQPHHCMTHDNSWPVAMKFMSIGASKIHDNRQVVMTLDHDVQNKSEANLKKYRQIEEFANTHGVDFYPAGRGIGHQIMVEEGYAWPGTVTVASDSHSNMYGGVGCLGTPMVRTDAASIWATGKTWWQIPPIAKVTFTGLLPPGVTGKDVIVALCGLFNNDDVLNHAIEFTGAEETMRSIPVDDRLTIANMTTEWGALSGLFPIDAVLASWMRAKATVTAMEHPELGDKAKFTHAKIDALLENPLVADPGATYAKQLYLNLSTLSPFVAGPNSVKIATPLKDLEAQNLKLDKAYLVSCTNSRASDIAAAARVFKDAAADNNGVIPKVAPGVKFYIAAASLLEQKQAEDSGDWQVLLDAGAEPLPSGCGPCIGLGTGLLEPGEIGISASNRNFKGRMGSTDAKAYLASPEVVAASALKGKIAGPGWYQKPEGVEKVIIGEGNGVVEQDKAMSIEDALDKIIAEAESLIANAEAGLTPESTSSSSSSSSSSEEESLTEILPGFPEAISGEIIFCDADNINTDGIYPGKYTYQDNITPAKMAEVCMENYDASFGSIARAGDILVTGFNFGCGSSREQAATAILAKQIPLVVSGSFGNIFSRNSINNALMGVEVPKLVQRLREEFGDKVATRRTGWKLTWDVRRSKVVVEEASGKKWEQKVGELPPNVQEIIARGGLEKWVKSQIEA
What is the function of this protein?
Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
What are the official names of this protein?
Homoaconitase, mitochondrial, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FTHS_BEII9
Sequence: MSSDLEIARAAKLRPIATVADEAKIPAEALHSYGLHVAKIDTSLLPKKDRPAKLVLVTAINPTPAGEGKTTTTIGLGDALRRLGKACVIALREPSLGPCFGTKGGATGGGYAQIVPMERINLHLTGDFHAITSAHNLLAALIDNHLYWGAEPKIDSRKVAWRRVLDMNDRALRQIVVGLGGGGNGYPRETGFDITAASEIMAIFCLSKDLADLQQRLAQIIVAQDVNKQPVRADALQAVGAMTVLLKDALMPNLVQTLEGTPTFVHGGPFANIAHGCNSVAATLAAMQLGDYVVTEAGFGADLGAEKFLDIKCRQAGIAPSAAVIVATARALKSHGGVAPADLNKENLDALKAGLANLGRHIANVKKFGLPVVVAINHFLSDTEAEQELIAHTCRDEYGVEAIDCRHWAAGGKGALALAEKVIALVEGGTAQFKMLYEDTLPLIEKMRRIAQEIYGAADISLDAKAKKQLADIEAQGFGHFPVCVAKTQYSFAADPKLLGAPTGHIVPIREVRLSAGAGFVVMICGDIMTMPGLSRQPAAWKIGLDAQGNIEGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: CCSA_POPTR
Sequence: MIFLTLEHILTHISFSVVSIVIIIHFLTLLVNEFVGLYDSSEKGMLTTFFCLTGLLITRWIYSGHLPISDLYESLIFLSWIFSIIHMVPYFKKHKNYLSTITAPSTFFTQGFATWGLLTDMHQSKILVPALQSQWLIMHVSMMVSGYAALLCGSLLSAALLVITFRKVIRIVGKNNNLLNDSFPVDEIQYMMEKKSILKNTFFPSSRNYYRFQLIQQLDHWGFRILSIGFLFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWTIFAIYFHTRTNKNLEGLNSAIVASIGFLIIWICYFGVNLLGIGLHSYGSFTLISN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYM_ECOLC
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLANELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_THEYD
Sequence: MTDRIPMTPEGYEKLKEELDRLIKIERPAIIKAIAEARAHGDLSENAEYHAAREKQSFIEGRIQELQAKLARAYVIDPSKINQNKVAFGAKVRVIDIDTEEEKEFHLVGPDEADVKNGKISITSPVGKALIGKEVGEQVTIKAPAKTFNYEIISISFE
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RL21_STAAU
Sequence: MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSXRKKGHRQPYTKLTIDKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: MFSD1_MOUSE
Sequence: MEDEDGEDRALLGGRREADSAVHGAPRALSALCDPSRLAHRLVVLSLMCFLGFGSYFCYDNPAALQTQVKRDMQVNTTKFMLLYAWYSWPNVVLCFLGGFLIDRIFGIRWGTVIFSCFVCIGQVIFALGGIFNAFWLMELGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYGKIEALLGSAGHMTLGVTLMIGCITCIFSLICALALAYLDRRAEKILHKEQGKTGEVIKLRDIKDFSLPLILVFVICVCYYVAVFPFIGLGKVFFMEKFRFSSQSASAINSIVYIISAPMSPLFGLLVDKTGKNIIWVLYAVAATLVSHMMLAFTFWNPWIAMCLLGFSYSLLACALWPMVAFIVPEHQLGTAYGFMQSIQNLGLAVIAILAGMILDSKGYLLLEVFFIACVSLSLLAVVCLYLVNRAQGGNLNYSAKQRERMKLSHPE
What is the function of this protein?
Lysosomal transporter which is essential for liver homeostasis (PubMed:31661432).  Required to maintain stability and lysosomal localization of GLMP (PubMed:31661432, PubMed:32959924).
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: CNOT7_MOUSE
Sequence: MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDFFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEASKQS
What is the function of this protein?
Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate.  Its function seems to be partially redundant with that of CNOT8.  Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Required for miRNA-mediated mRNA deadenylation.  Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
What are the official names of this protein?
CCR4-NOT transcription complex subunit 7, CCR4-associated factor 1, CAF-1.
What is the protein family that this protein belongs to?
Belongs to the CAF1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, P-body. Note=NANOS2 promotes its localization to P-body.
Protein: ADH1_MOUSE
Sequence: MSTAGKVIKCKAAVLWELHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHVVSGTLVTPLPAVLGHEGAGIVESVGEGVTCVKPGDKVIPLFSPQCGECRICKHPESNFCSRSDLLMPRGTLREGTSRFSCKGKQIHNFISTSTFSQYTVVDDIAVAKIDGASPLDKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYSKPIQEVLQEMTDGGVDFSFEVIGRLDTMTSALLSCHAACGVSVVVGVPPNAQNLSMNPMLLLLGRTWKGAIFGGFKSKDSVPKLVADFMAKKFPLDPLITHVLPFEKINEAFDLLRSGKSIRTVLTF
What are the official names of this protein?
Alcohol dehydrogenase 1, ADH-A2, Alcohol dehydrogenase A subunit.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_MACCJ
Sequence: MHFETVIGLEVHVELKTESKMFSASPAHFGAEPNTNVNVVDLGYPGVLPVVNKTAVDWAMRAAMALNMDIRTETKFDRKNYFYPDNPKAYQISQFDEPIGENGYIDIEVNGETKRIGITRLHMEEDAGKLTHKDGYSLVDLNRQGTPLVEIVSEPDIRTPEEAYAYLEKLKAIIQYTGVSDVRMEEGSLRCDANISLRPVGQEKFGTKAELKNLNSFSFVKKGLEHEVKRQEEVLLNGGEILQETRRFDESTGKTILMRVKEGSDDYRYFPEPDLVPLYIDEAWKERVRASIPELPDVRKAKYVSEYGLPEYDAHVLTLTKEMSDFFEAMIALDADAKLSSNWLMGGVNEYLNKNQKELHETALTPENLSEMVKLLADGTISSKIAKKVFADTVETGKAPKVIMEEQGLVQISDPEQLKAFVTEALDNNPQSIEDFKNGKGKATGFLVGQIMKISKGQANPQLVNKILREELEKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: SYV_NEIG1
Sequence: MLDKYSPAEIESKHYQNWESQGYFRPDMDLTKPSFSIQLPPPNVTGTLHMGHAFNQTIMDGLTRYYRMKGCNTAWIPGTDHAGIATQIVVERQLAAQNVSRHDLGREKFLEKVWEWKEVSGGTITQQMRRVGCSADWTREYFTMDGVRAETVTEVFVRLYEQGLIYRGKRLVNWDPVLGTAVSDLEVESMEEQGSMWHIRYPLADNPTEAVIVATTRPETLLGDAAVAVNPEDERYTHLIGKELILPLTGRTIPVIADEYVEKDFGTGCVKITPAHDFNDYEVGKRHDTRLINVFDLEAKVLANAEVFNFKGEAQPGFSLPEKYAGLDRFAARKQMVADLQEQGFLVEIKPHTLMTPKGDRTGSVIEPMLTSQWFVAMSATPNGGEPDNEFKGLSLADKAKKAVDSGAVRFIPENWVNTYNQWMNNIQDWCISRQLWWGHQIPAWYDEAGNVYVARNQAEAEKQAGKTGLTREEDVLDTWFSSALVPFSTLGWPSETDELKAFLPSNVLVTGYEIIFFWVARMIMMTTHFTGKVPFKAVYIHGIVRDHEGKKMSKSEGNVIDPVDLIDGIGLDKLLMKRTTGLRKPETAPKVEEATKKLFPEGIPSMGADALRFTMASYASLGRSVNFDFKRAEGYRNFCNKIWNATNFVLMNTENQDCGYGATAAEPRGHSFPDMWIIGRLNQTIEQVTQAYETYRFDLAAETLYSFVWNDYCDWYLELAKVQLQTGCASRQRATRHTLLRVLEAALRLLHPIIPFITEELWQTVAPMCDAKTADSIMLARFPETDGGEIVQTAFGQMTVLQDLIGAVRNLRGETGIQPNVKAPLFVESADDLADYLKYLPMMTRLTEARQVAALPESGDAPVAVCNGARLMLKVEIDKAAETARLSKEAEKLQKALDKLNAKLSKPGYTEKAPAHLVEKDKADLAELEDKMAKVQNQLAKLKD
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y666_TREPA
Sequence: MQKGSGASSVMTLYEYYLIFPDGECREISGPPCERSLLDMNGHPLRVPLSSNRVIAYRVAGKRTVAGGRGVVGIWYTLEQLDALELLEYVSGPLGQR
What are the official names of this protein?
Uncharacterized protein TP_0666.
Protein: TEDM1_HUMAN
Sequence: MILKGCLLYPLCSPRNKQRCARLWKIAYGGLLKIVTGSLLTFYVVLCLDGGMVLMRKQVPSRFMYPKEWQHLTMFILLTLNGCVDFMSKNVLPQRCVGLEKGTLVLIIYELLLLMVSHVKDSEGVELHVYSLLILVVFLLLLVLTAELWAPNMCHLQLMETFLILMMGSWLMQAGFILYRPVSGYPWQDDDISDIMFVTTFFCWHVMINASFLLGIYGFSSFWYHCFRPSLKLTGPKEAPYYASTPGPLYKLLQEVEQSEKEDQALLLPKSSP
What are the official names of this protein?
Transmembrane epididymal protein 1, Human epididymis-specific protein 9, He9.
What is the protein family that this protein belongs to?
Belongs to the TMEM45 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HBA_MESAU
Sequence: VLSAKDKTNISEAWGKIGGHAGEYGAEALERMFFVYPTTKTYFPHFDVSHGSAQVKGHGKKVADALTNAVGHLDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLANHHPADFTPAVHASLDKFFASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GATB_MYCGE
Sequence: MINFEAIIGIEVHVVLNTASKMFSKAPNRVDNQKINHFIDPIDLGLPGTLPQVNELAVYKALLLADALKMKTVTNKLVFDRKHYFYQDLPKGFQITQQNYPFAKNGVVTINVDAIEKPIYIDRFHLEEDTAKQHFNHDQILLDFNRCGAPLIEVVTLPVINTAKEAKAYLQKLRQILIVNNISNAKLEDGSMRSDCNVSVRLKGQRQLGTKIEIKNINSLNNVEKAIDLEINRQVKALINGETLSQATLSFDDKTNNNVFMRKKDNTIDYRYFIEPNIMTSNIDDLLLEKPVAFQLEQFQKELIDSNVNPQLVQLVVDDATIFSAFQTINSVIKNPQETIRWLCIELIGQLNKTNSSLTANLIQDLITLIEMLKAAKVNQKQAKQLITLMIETKKDPKSLAKLHNLEQITDPKELQKIIKKIFQENEKEILKNIDRIERIQKLIIGQVMHKTNNRANPQQVFIIVENMLHEVRERDS
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: MNMC_SHEPC
Sequence: MTAEPNKPCQIKRDYPQLINLYPATAHNDAHYLSKLSIYQQRVFEAHSQQKLLVLGQMGLGNGLELLSWWRTQTNPNQRLLLKVFEPNPINAYELKLLWDQSASLAKVPELELLAQCLLHTEPTAIIGCQRLIFDDGRTTIDLHFGDIQSQLSSLIHSPLHPVQHWLVLPHLQNGLHQQIHWQMAKLSDDSATVATIGLNESSGLSETTVNRFQACGFEVRDFTCAEIQTNPQPDAILLHERHVLRRQDAKAYAFNPMAAILSSDAPSSIAIIGGGLASAHLALSLAERGQSTQIFCKDAKLGQGASGNRQGAIYPLLTPENDELSRFFQQAFLFSRRRVQALTSAPAPNQTPISHNFCGVLQTAHDERSQLRLDKIIQSQNWPSEIAYRVDAQQANCLANINIDKSGFFYPLAGWVCPYEYAEAALQKAQQLTAVKLHLETEILEIEHQSEGWYLITAKHRFGPFAQVVLANGAALTQFDASNKLQISPFRGQVSHVPAQFQLSQLATVLCANGYLTPSHEGLHCLGASYVKEPKHLDFCPQEQQENLAKMHESYPNQPWLEDIDMSGNNARVGVRMVTRDHFPMMGCAPDVAQIIKDYAEHQLTKESRHYWQTTPAPVHEGLYILGGLGSRGLSSGPLAAECLAAQLCGEPIPLDKATLCKLNPNRMWLRKLLKGKAL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYBG_ECOLI
Sequence: MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Involved in the biosynthesis of the Fe(CN)(2)CO cofactor (PubMed:16412426).  HybG delivers iron-bound CO(2) to HypD where reduction to CO probably occurs (PubMed:23851071).  In complex with HypD, accepts the cyanide ligand generated by HypF and HypE, and also coordinates the carbon monoxide ligand (By similarity).  Involved in the maturation of the hydrogenase 2.  Also participates in the maturation of hydrogenase 1 (PubMed:11292801).
What are the official names of this protein?
Hydrogenase maturation factor HybG, Hydrogenase-2 operon protein HybG.
What is the protein family that this protein belongs to?
Belongs to the HupF/HypC family.
Protein: LEU3_BORPE
Sequence: MTHQIAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHAVLFGAVGDWKYDTLPREFRPEQAILGLRKALGLFANLRPAILYPELASASSLKPEIVSGLDILIIRELTGDIYFGTPRGVRTAADGAFAGEREGYDTMRYAESEVRRIARIGFESARKRNKKLCSVDKANVLETSQFWRDLVIEVSRDYLDVELSHMYVDNAAMQLVRNPRQFDVIVTGNLFGDILSDEAAMLTGSIGMLPSASLNAAGQGLYEPSHGSAPDIAGQGIANPLATILSAAMLLRYSLNLAPQADRVEAAVRKVLADGLRTADIHEAGTTKVSTSQMGDAVLKALG
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRA_VIBVY
Sequence: MITIKKGLDLPIAGAPSQVINDGKSITKVALLGEEYVGMRPTMHVRVGDEVKKAQVLFEDKKNPGVKFTSPVSGKVIEVNRGAKRVLQSVVIEVAGDEQVTFDKFEASQLAGLDREVIKTQLVESGLWTALRTRPFSKVPAIESTTKAIFVTAMDTNPLAAKPELIINEQAEAFVAGLDVLSALTEEKVYVCKSGTSLPRSSQSNVEEHVFDGPHPAGLAGTHMHFLYPVNANNVAWSINYQDVIAFGQLFLTGELFTDRVVSLAGPVVNNPRLVRTIMGASLDELTDSEMMPGEVRVISGSVLTGTHATGPHAYLGRYHLQVSVLREGRDKELFGWATPGKNKFSVTRSFLGHLFKGQLFNMTTTTNGSDRAMVPIGNYERVVPLDMEPTLLLRDLCAGDTDSAQALGALELDEEDLALCTFVCPGKYEYGQLLRDCLNTIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: MAST1_PROEX
Sequence: INWLKLGKKVSAIL
What is the function of this protein?
Mast cell degranulating peptide.  Has hemolytic activity.  Its both activities may be due to pore formation.
What are the official names of this protein?
Mastoparan-1, Mastoparan I, MP-I.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Mastoparan subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a membrane channel in the prey.
Protein: PLSX_DELAS
Sequence: MITLAVDCMGGDHGPRVTLAACRQFLDSHSDARLLLVGQPDALAGFAHERASVVPASEVVGMDDPIEVALRRKKDSSMRVAIQQVKDGQAAAAVSAGNTGALMAISRYLLKTLDGIDRPAIAPQLPNAKGGATTVLDLGANVDCSAEHLLQFAVMGSALVSALNNEEAPSVGLLNIGEEQIKGSEVIKRAGELLRAAGKAGHLNFYGNVEGNDIFKGTTQVVVCDGFVGNVALKSSEGVASMISNALKQEFKRNIFTKMAAIVAYPVLTALMKRVDHRRHNGAALLGLRGLVFKSHGSADALAFEHALNRAYDAARNNLLDRVRTRISAALPLLLAAQSESGPSAP
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RNPA_HELP2
Sequence: MPDELRAEKSFPSKPYDSLKNKSEFDKVYQKGFKKHNPFFSLFVLDLSKEPPKEKEGFKDPLSCRLKDKKALYLLGLSVSKKVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDCYHLDFWALEKHFLEMLTSIKNYMNKALKGLKKGMTHTYAKQ
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: COXX_BRUSU
Sequence: MEKNTASEDAFALSEATARDYLVLLKPRVMSLVVFTGLVGLVLAPGHMNPVLAVISILCIAVGAGASGALNMWYDADIDAVMKRTRKRPIPAGIIAPNQVLAFGLTLSAFSVMTLGLMVNWLAAALLAFTIFFYAVIYTMWLKRSTPQNIVIGGAAGAFPPMIGWAAATGEITWDSLVLFMIIFLWTPPHFWALSLFTTNDYEAARIPMMPNVKGELSTRRQALFYAVLMAPVGVLPWVMGFAGMFYGVVSTLLGLAFVYYAWRLWAADSQPQMLAAARKLFRFSLLYLAGIFAVLLFEALTFKLLAAFGVF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PPTA_ENT38
Sequence: MPHVDIKCFPRDLNDEQKTALAADIAEVIIRHFNSKDSSVSVALNQVQQEDWKAQVWDTEIGPKLDELIKKPGYSM
What are the official names of this protein?
Tautomerase PptA.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family. PptA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.