PharMolix/UniProtQA huggingface dataset:
Protein: TTCA_STRM5
Sequence: MTAVISLPDPPQRASRGPRVAGPGQDRLGKRLRRQVGQAIADFGMIEAGDKVMVCLSGGKDSYTLLDLLLQLQKRAPVPFELVAVNLDQKQPGFPEHVLPEYLAALGVPYQIIEQDTYSVVSRVIPEGRTMCSLCSRLRRGALYNHAKAHGFTRIALGHHCDDMVATLFMNLFHHAKLAAMPPKLLSDDGQHVVIRPLAYVREHDIAEYAQARRFPIIPCTLCGSQESLQRRQVGLMLKQWDQDHPGRIEQIARAMADVRPAQLADATLFDFRALGHSGHAAHADAWLADAVPETPAD
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_PYRFU
Sequence: MLGYNEKLVLLKLNEVKKARIEELVKLTGLEQVAIMRALLTLEKEGLAKISERKERIIRLTDLGRKYIQMGLPEIRALNVLKSKKKVKLDELRGVLTEDELKPIVGILRKEGWVKVEKTPEGLVLEITERGENPEERPIDKALKILSEKEYATSEEISKIVPINELKRRKVAQEEEVVERIAEITEKGVELVKKGIELKREVTSLTPELIASGKWREVEFKPFNIKAPVKKIYPGKKQPYRVFLDKIRRKLIEMGFIEITVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPNRELVERVKEAHERGLAGSRGWGYVWSPERAMFLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAAEDLTFRHLLGILKKFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTKALGIDVPVIAWGIGIDRLAMFRLGIDDIRYLFSYDLKWLREAKLIW
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_LEUMM
Sequence: MNLNELQPAAGSRHVRNRVGRGTSSGNGKTSGRGQKGQKARGKVRLGFEGGQMPLYRRIPKRGFTNISRKEFAVVNLNKLNSFDDGTEITPTLLIENGIVKNQKSGIKILAVGQLEKKLTVKAHKFSAAAVAAIEQAGGSTEVL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: CC167_BOVIN
Sequence: MTKKKRENLGVALEIDGLEKKLSQCRRDLEVVNSRLCGVELSSEARRSLEKEKSSLMNKASNYEKELKLLRQENRKNMLLSVAIFLLLTVIYAYWAL
What are the official names of this protein?
Coiled-coil domain-containing protein 167.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DNLJ_CORGL
Sequence: MTEDNAQLRRTWNDLAEKVRYHRDRYYNEQPEIPDADFDALFKQLQQLEEDHPELAVPDSPTMVVGAPVAEQSSFDNVEHLERMLSLDNVFDEQELRDWLGRTPAKQYLTELKIDGLSIDLVYRNGQLERAATRGDGRVGEDITANARVIEDIPHQLQGTDEYPVPAVLEIRGEVFITVEDFPEVNAQRIADGGKPFANPRNAAAGSLRQKNIEDVKKRRLRMISHGIGFTEGFSPASQHDAYLALAAWGLPTSPYTEAVTDPEDVVKKVSYWADHRHDALHEMDGLVIKVDDIASQRALGSTSRAPRWAIAYKYPPEEVTTKLLDIQVGVGRTGRVTPFAVMEPVLVAGSTVSMATLHNQSEVKRKGVLIGDTVVIRKAGEVIPEVLGPVVELRDGTEREYIFPTLCPECGTRLAPAKADDVDWRCPNMQSCPGQLSTRLTYLAGRGAFDIEALGEKGAEDLIRTGILLDESGLFDLTEDDLLSSNVYTTNAGKVNASGKKLLDNLQKSKQTDLWRVLVALSIRHVGPTAARALAGRYHSIQALIDAPLEELSETDGVGTIIAQSFKDWFEVDWHKAIVDKWAAAGVTMEEEVGEVAEQTLEGLTIVVTGGLEGFTRDSVKEAIISRGGKASGSVSKKTDYVVIGENAGSKATKAEELGLRILDEAGFVRLLNTGSADE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DAPD_MANSM
Sequence: MSNLQSIIEAAFERRAEITPKTVDAQTKAAIEEVIAGLDCGKYRVAEKIDGDWVTHQWLKKAVLLSFRINDNQLIDGAETKYYDKVALKFADYTEERFQQEGFRVVPSATVRKGAYIAKNTVLMPSYVNIGAFVDEGTMVDTWVTVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIGDNCFIGARSEIVEGVIVEDGCVISMGVFIGQSTKIYDRETGEVHYGRVPAGSVVVSGSLPSKDGSHSLYCAVIVKKVDAKTLGKVGLNELLRTIEE
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF48_SYNJA
Sequence: MAKMLKLWRLVLLAAFSLLLMAARMPDMKVVPWQQVEVPTQNILLDIAFTGTNPSHGWLVGDKATLLESQDGGLHWQVRKLTALEPEAYLSSISFAGAEGWVVGQPRILLHTLNEGSDWTSIRLSKQLPGEPILIQALGPGAAEMVTNVGAIYRTEDGGQTWHAQVEEPIGAIKNIARGPGGEYLAVSSRGSFYFLYTPESRSWKPYPRESSRRIQNMGFGPNGSAWKLNQGAEIAFTSDFTSGEWSKPLRPGRALSFGYLNAAYQNDHDLWVVGGGGTLIHSPDGGKTWEEAKKLSNIPANFYSIEFFGPDRGFILGQRGTLLRYVGYSNSPS
What is the function of this protein?
A factor required for optimal assembly of photosystem II (PSII), acting in the early stages of PSII assembly.  Also plays a role in replacement of photodamaged D1 (psbA).  Assists YidC in synthesis of chlorophyll-binding proteins.
What are the official names of this protein?
Photosystem II assembly protein Ycf48.
What is the protein family that this protein belongs to?
Belongs to the Ycf48 family.
What are the subcellular locations of this protein?
Cellular thylakoid lumen. Note=Associated with a PSII precusor complex on the lumenal side of the thylakoid membrane.
Protein: SAPK2_ORYSJ
Sequence: MERYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQKIDENVQREIMNHRSLRHPNIVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQICHRDLKLENTLLDGSIAPRLKICDFGYSKSSLLHSQPKSTVGTPAYIAPEVLARKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYMVPDYVRVSMECRHLLSRIFVANPEQRITIPEIKNHPWFLKNLPIEMTDEYQMSVQMNDINTPSQGLEEIMAIIQEARKPGDGSKFSGQIPGLGSMELDDVDTDDIDVEDSGDFVCAL
What is the function of this protein?
May play a role in signal transduction of hyperosmotic response (Probable).  Can phosphorylate BZIP46 in vitro (PubMed:22301130).  Together with ABI5, PP2C30 and PYL5, is part of an abscisic acid (ABA) signaling unit that modulates seed germination and early seedling growth (PubMed:22071266).
What are the official names of this protein?
Serine/threonine-protein kinase SAPK2, Osmotic stress/abscisic acid-activated protein kinase 2, stress-activated protein kinase 2, OsSAPK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RK36_AETGR
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRAI5_ECOLX
Sequence: MIAKHVPMRSLGKSDFAGLANYITDAQSKDHRLGHVQATNCEAGSIQDAITEVLATQHTNTRAKGDKTYHLIVSFRAGEQPSADTLRAIEERICVGLGYGEHQRISAVHNDTDNLHIHIAINKIHPTRHTMHEPYYPHRALAELCTALERDYGLERDNHEPRKRGAEGRAADMERHAGVESLVGWIKRECLDEIKGAQSWQELHQVMRDNGMELRVRANGLVFEAGDGTMVKASTVARDLSKPSLEARLGPFEASPERQAQTTAKRQYRKDPIRLRVNTVELYAKYKAEQQSLTTARAQALERARHRKDRLIEAAKRSNRLRRATIKVVGEGRANKKLLYAQASKALRSEIQAINKQFQQERTALYAEHSRRTWADWLKKEAQHGGADALAALRAREAAQGLKGNTIRGEGQAKPGHAPAVDNITKKGTIIFRAGMSAVRDDGDRLQVSREATREGLQEALRLAMQRYGNRITVNGTVEFKAQMIRAAVDSQLPITFTDPALESRRQALLNKENTHERTERPEHRGRTGRGAGGPGQRPAADQHATGAAAVARAGDGRPAAGRGDRADAGLHAATVHRKPDVGRLGRKPPPQSQHRLRALSELGVVRIAGGSEVLLPRDVPRHVEQQGTQPDHALRRGISRPGTGVGQTPPGVAAADKYIAEREAKRLKGFDIPKHSRYTAGDGALTFQGTRTIEGQALALLKRGDEVMVMPIDQATARRLTRIAVGRDAVSITAKGSIKTSKGRSR
What is the function of this protein?
The initiation process of transfer DNA synthesis requires the interaction of at least three plasmid-specific components (TraH, TraI, and TraJ) at the transfer origin resulting in the assembly of a specialized nucleoprotein complex - the relaxosome.  Site and strand specific cleavage at the transfer origin is dependent on TraI and TraJ.
What are the official names of this protein?
Protein TraI.
Protein: HSLV_ECOL6
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDICIYTNHFHTIEELSYKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA4_PETHY
Sequence: MSRRYDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGISSKDGVVLVGEKKVTSKLLQTSTSSEKMYKIDDHVACAVAGIMSDANILINTARVQAQRYTFSYQEPMPVEQLVQSLCDTKQGYTQYGGLPPFGVSFLFAGWDKNFGFQLFMSDPSGNYAGWKAAAIGANNQAAQSMLKQDYKDDITREEAVQLALKVLSKTMDSTSLTSEKLELAEVFLSNGKVKYQACSPEKLNSMLVKSGLTQPSAEES
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-4, 20S proteasome alpha subunit C, 20S proteasome subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PSD_DESPS
Sequence: MLQPQVPVAREGVPFIGFAAFLTLVSAASECEILTFIFLLATAFTLYFFRDPERFVPDDPSALISPADGKIIVIEKTDKQDFIEGEALKISIFMNVFNVHVNRAPIAGKVDKIIYTPGKFYSADSSQGAEYNENCGIVLTTNSGKKIAFVQVAGLIARRIVCWLEPNDTIQSGRRVGLIRFGSRVDLYLPTDTALSVSVGDKVRAGETILGQII
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DNLJ_METPB
Sequence: MPRTQASAAVESLSEDAAQARHAELSRAIERANHLYYNEDAPELTDAEYDALRQELEAIEARFPALTGTTEASAGVGAKPSEKFAKVRHAVPMLSLGNAFADEDVDEFVARVRRFLNLTAEEPVAFTAEPKIDGLSLSLRYEAGRLVTAATRGDGEVGENVTANALTVEDIPATLSGKDIPEVLEVRGEVYLSHEDFAGINARQEAAGKPLFANPRNAAAGSLRQLDPAITASRPLRFFAYAWGEVSEPFTDTQSAVLERFRGWGLPVNPRTKLCRSAEEMIAHYRAIEAERAGLGYDIDGVVYKVDDLGFQRRLGFVSRAPRWALAHKFAAQEAITELLAIDINVGRTGSLNPLARLKPVTVGGVVVSNATLHNEGYVQGVGADGEPIREGRDIRVGDTVIVVRAGDVIPKVMDVVLDKRPADAVPYVFPETCPACGSRAVRELNPRTKKLDAIRRCTGGLICPAQGVERLKHFVSRNGFDLEGFGQTYIEVLFEAGLVKQPADLFRLEFEPLKAAIVARREALSAQRRAEGEPAPKKPTKKKGEEEDKAIKNLLASLEARRKIALNRFLFALGIPQIGESTAKALAKRFPDMPALMAALEAATREQAGRDWLELSALPRIGPGTRDRLFETLDPLPGEAMQDLSLGARLRGRLTPSQREAVLAHYGSEEEADAALERAASQRPGDAYRLFADDGEIGPVATDSLIQFFSEPHNDAAVRALLEEVGTEPLAATTSAAAFAGKTVVFTGTLEKMTRSEAKATAERLGAKVSGSVSAKTDLVVAGPGAGSKLKDAERHGVKVVSEDDWLAMLAEA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: HEXA1_DICDI
Sequence: MIKKIILFFAVLIAIVIGQQPLNVVPYPQQVSIGTCVIPVAPGSILIESNIESATFSVSMDRYTNLFFPFSNESEPSSNESFLLSVTIYSDDETLQLGIDESYSLSIEQGSYQLKATNIYGAMRGLETFKQLIVYNELENSYSIVCVSISDSPRYPWRGFMVDSARHYIPKNMILHMIDSLGFSKFNTLHWHMVDAVAFPVESTTYPDLTKGAFSPSATFSHDDIQEVVAYAKTYGIRVIPEFDIPGHAAAWGIGYPELVATCPDYAANVNNIPLDISNPATFTFIQNLFTEIAPLFIDNYFHTGGDELVTGCWLEDPAIANWMTKMGFSTTDAFQYFENNLDVTMKSINRTKITWNDPIDYGVQLNPETLVQVWSSGSDLQGIVNSGYKALVSFAWYLDKQNPDNNIHYEWQDTWQDFYAADPTNNISTNAENIIGGEATMWAEQINQVNWDVRVWPRAIGIAERLWSAQSVNSVSLALPRIGHFTCDLSRRGIQSGPLFPDYCPMQDDLVFTMKPNTKLSKSEIKLILNK
What is the function of this protein?
Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines.  This enzyme plays a role during the slug stage of development in the maintenance of pseudoplasmodia of normal size.
What are the official names of this protein?
Beta-hexosaminidase subunit A1, Beta-N-acetylhexosaminidase subunit A1, N-acetyl-beta-glucosaminidase subunit A1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: PER62_ARATH
Sequence: MGLVRSFALVIVFLSCLIAVYGQGTRIGFYSTTCPNAETIVRTTVASHFGSDPKVAPGLLRMHNHDCFVQGCDGSVLLSGPNSERTAGANVNLHGFEVIDDAKRQLEAACPGVVSCADILALAARDSVSLTNGQSWQVPTGRRDGRVSLASNVNNLPSPSDSLAIQQRKFSAFRLNTRDLVTLVGGGHTIGTAACGFITNRIFNSSGNTADPTMDQTFVPQLQRLCPQNGDGSARVDLDTGSGNTFDTSYFINLSRNRGILQSDHVLWTSPATRSIVQEFMAPRGNFNVQFARSMVKMSNIGVKTGTNGEIRRVCSAVN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 62, Atperox P62, ATP24a.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SPEE_PROM3
Sequence: MDSPSTTASGWIDEHHQGVRYGLQGRVLVDEKSPYQRITVIDSSRYGKGLLLDGCWMTAEHQERHYHESLVHPALCSAAQLERVLVIGGGDGGTARECLRYQDVKHLDMVEIDGRVVELSQKHLPSIGGHAWSDARLQLNLEDGIAWTANATDSSYDVILVDGSDPTGPAEGLFNEAFFKQCRRILRPGGVFATQSESPEAFRQIHIDTVRLIRQVFGYADPLYGWVPMYPSGWWSWTFAAVDGPRYRNPLPARAAAISSGCEIWSPRWQQGAFEAIPAFIERELT
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODP2_YEAST
Sequence: MSAFVRVVPRISRSSVLTRSLRLQLRCYASYPEHTIIGMPALSPTMTQGNLAAWTKKEGDQLSPGEVIAEIETDKAQMDFEFQEDGYLAKILVPEGTKDIPVNKPIAVYVEDKADVPAFKDFKLEDSGSDSKTSTKAQPAEPQAEKKQEAPAEETKTSAPEAKKSDVAAPQGRIFASPLAKTIALEKGISLKDVHGTGPRGRITKADIESYLEKSSKQSSQTSGAAAATPAAATSSTTAGSAPSPSSTASYEDVPISTMRSIIGERLLQSTQGIPSYIVSSKISISKLLKLRQSLNATANDKYKLSINDLLVKAITVAAKRVPDANAYWLPNENVIRKFKNVDVSVAVATPTGLLTPIVKNCEAKGLSQISNEIKELVKRARINKLAPEEFQGGTICISNMGMNNAVNMFTSIINPPQSTILAIATVERVAVEDAAAENGFSFDNQVTITGTFDHRTIDGAKGAEFMKELKTVIENPLEMLL
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex component E2, PDC-E2, PDCE2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CYOE1_PSEE4
Sequence: MATLLSTERPRTGWRDYMELTKPKVVVLMLITSLVGMFLATRAGVAWSVLLFGNLGIGLCAGGAAVVNHVVDRRIDALMARTHKRPLAQGRVAPLPALAFALLLAVMGLALLLAFTNTLTAWLTLASLLGYAVLYTGFLKRATPQNIVIGGLAGAAPPLLGWVAVSGHVSAEPLLLVLIIFAWTPPHFWALAIHRKAEYEKADIPMLPVTHGEHYTALHILLYTLILLAVSLLPYAIHMSGPLYLACALALGLRFLHWAWVLYRGTRPHAAIKTFKYSIGYLFALFIALLVDHYLLLNL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 1, Heme B farnesyltransferase 1, Heme O synthase 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RK36_PINKO
Sequence: MKIRASIRRICGKCRPIRRRKRVMIICSNPRHKQKQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AUSK_EMENI
Sequence: MTGTRILELFGPAPEPPSELGRYRILSPTAGIRVSPLQLGALSIGDAWSTDLGSMDKDSAMELLDAYAAAGGNFIDTANAYQNEQSEMWIGEWMASRGNRDKMVIATKFGTDYRAHELGKGLAVNYSGNHKRSLHMSVRDSLQKLRTSWIDILYLHTWDYTTSIPELMDSLHHLVQRGDVLYLGICNTPAWVVSAANTYAQQQGKTQFSVYQGRWNPLRRELERDILPMARHFGMAVTVYDALGSGKFQSRDMLARRKDQGEGLRAIYGGQQTALEEAMSKALGVVAAQHGIESVTAVALAYLLAKAPYVFPIIGGRKIQHLHDNIEALSLRLSQEEIEYLESVGDFDPGFPYDMAGVDPADTGIATPIVAQAAPMAFVQRSKAIGYAESSKGSQMFG
What is the function of this protein?
Aldo-keto reductase; part of the gene cluster B that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids (PubMed:22329759).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (PubMed:22329759).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (PubMed:22329759).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (PubMed:22329759).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (PubMed:22329759, PubMed:23865690).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (PubMed:22329759).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (PubMed:22329759).  Finally, the cytochrome P450 monooxygenase ausG modifies austinolide to austinol (PubMed:22329759).  Austinol can be further modified to dehydroaustinol which forms a diffusible complex with diorcinol that initiates conidiation (PubMed:22234162, PubMed:22329759).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end products of the Emericella nidulans austinoid biosynthesis clusters are austinol and dehydroaustinol, even if additional enzymes, such as the O-acetyltransferase ausQ and the cytochrome P450 monooxygenase ausR are still functional (PubMed:29076725).
What are the official names of this protein?
Aldo-keto reductase ausK, Austinoid biosynthesis clusters protein K.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: KLKB1_MOUSE
Sequence: MILFNRVGYFVSLFATVSCGCMTQLYKNTFFRGGDLAAIYTPDAQYCQKMCTFHPRCLLFSFLAVTPPKETNKRFGCFMKESITGTLPRIHRTGAISGHSLKQCGHQISACHRDIYKGLDMRGSNFNISKTDNIEECQKLCTNNFHCQFFTYATSAFYRPEYRKKCLLKHSASGTPTSIKSADNLVSGFSLKSCALSEIGCPMDIFQHSAFADLNVSQVITPDAFVCRTICTFHPNCLFFTFYTNEWETESQRNVCFLKTSKSGRPSPPIPQENAISGYSLLTCRKTRPEPCHSKIYSGVDFEGEELNVTFVQGADVCQETCTKTIRCQFFIYSLLPQDCKEEGCKCSLRLSTDGSPTRITYGMQGSSGYSLRLCKLVDSPDCTTKINARIVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGGILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPICLPSKADTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILEKTQSSDVRALETSSA
What is the function of this protein?
The enzyme cleaves Lys-Arg and Arg-Ser bonds.  It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface.  It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
What are the official names of this protein?
Plasma kallikrein, Fletcher factor, Kininogenin, Plasma prekallikrein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasma kallikrein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ALDOB_SHEEP
Sequence: MAHQFPALTSEQKKALSETARRIVANGKGILAADESVGTMGNRLQRIKVENTEENRRQFRELLFTVDSSVSQSIGGVILFHETLYQKDGQGKLFRDILKEKGIVVGIKLDQGVAPLAGTNKETTVQGLDGLSERCAQYKKDGADFGKWRAVLKIDNQCPSHLAIQENANTLARYASIYQQNGLVPIVEPEVIPDGSHDMEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFLSGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAENKKATQEAFMKRALANSQAAKGQYVHMGSSDSASTQSLFTASYTY
What are the official names of this protein?
Fructose-bisphosphate aldolase B, Liver-type aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Protein: HFQ_HAES1
Sequence: MAKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARSVSHHNSVQHHHIVQTQEMQVEALAENQTE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: XYLA_HAEIE
Sequence: MTTYFDKIEKISFEGEKSTNPFAFKHYDANQVILGKTMAEHLRLAVCYWHTFCWNGNDMFGLGSLERSWQKNSNLLAGAEQKADIAFEFLNKLGVPYYCFHDVDIAPEGNSVREYVQNFHHIVDILERKQVETGVKLLWGTANCFTNPRYMSGAATNPNPEVFAWAATQVFNAMNATQRLGGENYVLWGGREGYETLLNTDLKREREQIGRFMQMVVEHKHKIGFKGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHTFQHEIATACALDIFGSIDANRGDPQLGWDTDQFPNSVEENTLVMYEILKHGGFTTGGFNFDAKIRRQSIDPYDLFYAHIGAIDVLALSLKRAAKMLQEETLQKIVNERYAGWNSELGQHILQGKTSLETLAQLVQQKDLAPKPVSGQQEYLENLVNQVIYS
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_ECOL6
Sequence: MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEERDDLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQILADEVGAEVIALSDIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQEASEFMAWLRAQSASETIRDYRSQAEQVRDELTAKALAALEQGGDAQTIMQDLAWKLTNRLIHAPTKSLQQAARDGDNERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CBRB_ECOL5
Sequence: MSVSRRVIHHGLYFAVLGPLIGVLFLVLYIFFAKEPLILLVIIQVLPLFLLMSITTGAIPAMLTGVMVACLPEKIGSQKRYRCLVGGIGGVVITEIYCAVIVHIKDMASSALFENILSGENLVVRIIPALLAGVVMSRIITRLPGLDISCPETDSLS
What are the official names of this protein?
Inner membrane protein CbrB.
What is the protein family that this protein belongs to?
Belongs to the CbrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.