PharMolix/UniProtQA huggingface dataset:
Protein: KPRS2_LACPL
Sequence: MSTDQSYAKLKLFALNSNLPLAEKIAQRVGIPLGKSSVKRFSDGEIQINIEESIRGAEVFVIQSISEPVNDTILELLIMIDALRRASASQINVVIPYYGYSRQDRKARSREPITAKLIATLLEKDRASRVLTVDLHAAQIQGFFDIPVDHLFAAPLLASYFKDRGITDNLVVVSPDHAGVSRARKMAELLGAPIAIIDNRHPDDDDLVPSSIIGDVKGRVAIVIDDMIDTGTRFDVSADALAQAGAATVYGCATHAIFSQDAVAKLQASKFEKVIVTDTIQIPADKHFDKLVQLSVGPLLGDAIKLVHEQQPVDRLFDPRI
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Putative ribose-phosphate pyrophosphokinase 2, RPPK 2, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 2, Phosphoribosyl diphosphate synthase 2, Phosphoribosyl pyrophosphate synthase 2, P-Rib-PP synthase 2, PRPP synthase 2, PRPPase 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOOK_DROSE
Sequence: MSAPKNEMYYSLLEWFKTLNLNAPHADAESLADGVALAQALNQFAPESFTDAWLSKIKASAVGSNWRLRMSNLKKVTQSVYDYYSDVLNYSLSDFSKPDLQRIAEKCDLGELERLLQLVLGCAVNCAEKQSYITEIMCLEEELQANIMRALQELEATRQASTPEGGVASSLSRGSRTGLLDSKAVQEDRDALAQKCFETEKKMLLLIDEKTNLQQELHKLQQEFARLEQHSTVIGDDGVSLGPVQTGSVRYNELRRQLDLLKEELLQSEGAREDLKIKAQQQDTDLLHMQMRIEELMKSSAEVTTLKDEVDVLRESNDKLKICEAQLDTYKKKLEDYNDLKKQVKILEERSADYVQQNAQFEEDAKRYANTKGQVELFKKEIQDLHAKLDAESSKNVKLEFDNKNLEGKNLALQRAKDSLLKERDNLREAVDELKCGQLSSNTALTGTTVSRELQPSATVEKLQRLEAENKALREGQGGQTALAQLLDDANKRCENLREQLKTANERILSLSHASQSDDPILKESEFGKQIKQLMELNEQKTLQLEEAVTQSTSLQCKVTQLETNLSAREQEILVYDAKYRKCVEKAKEVIKSIDPRIASALDASVLEKSADLVEAEPKPKMSVMEEQLMTSAFYRLGVNAQRDAIDSKLAILMGSGQTFLARQRQSAPRKSLSAMKSK
What is the function of this protein?
Involved in endocytic trafficking by stabilizing organelles of the endocytic pathway.  Probably acts as a cytoskeletal linker protein required to tether endosome vesicles to the cytoskeleton.  Involved in modulation of endocytosis at stages required for down-regulation of membrane proteins that control synapse size.  Not involved in synaptic vesicle recycling.  Required in R7 cells for boss endocytosis into multivesicular bodies (MVBs).  Has a role in regulating adult longevity.
What are the official names of this protein?
Protein hook.
What is the protein family that this protein belongs to?
Belongs to the hook family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Endosome. Synapse. Note=Enriched at neuromuscular synapses, in both presynaptic and postsynaptic regions.
Protein: Y13A_METJA
Sequence: MRLTIEVIKERIVERKLFKRNRKSIEVKILAGLLYYLGLSLRKVSLFLSQFEDISHESVRIYYHKIKEVLNRFPSNSKFDTVVSWIKSFMMFYNWVKSLT
What are the official names of this protein?
Uncharacterized protein MJ0139.1.
Protein: TAUB_PARPN
Sequence: MQTLKVSDVSLIYPGHHKGAPVTALKGVNLEVKSGDFVVALGASGCGKTTLLNLMAGFMAPSAGQITLGDRPVAGPGAERGVVFQKHALLPWLNVIDNVEFGLKLQGVDARTRRERAVKNLALVGLQDFHKHMIYHLSGGMQQRVGIARALTCDPAMLLMDEPMAALDALTRETVQELLLQIWQQTDKMYFFITHSVEEALFLGSRLIVMSPRPGRITHTYELDFNRRFLAEGNARAIKSSPDFIEMREQILGIIYGDERAGEQEKIHA
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS13_STRP2
Sequence: MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVRVRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNTKNNARTRKGKAVAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GCH1L_CLOPE
Sequence: MKLNDIINIIEDIAPVNLKEGFDNVGLMVGDREKNITKILLALDCTEEVIKEAKEMGAELILTHHPLLFRKPSTITTDTLLGRKIISLIKNDINLYSAHTNWDSVKGGLNDTLVEILGFNKGIIMDKSPVDSEAGIGRVVELTKEMTVLEIINLIKSSLGVKNLRYAGDLNEVIKKIAIVNGSGQDFFGDAKKLGADLIITGDTTYHFVSDYKEMGLNILDIGHFNSEWPVLIKVSEKVKERLDSDVEFIVSKEAKDPFEFI
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: LSRK_ECOHS
Sequence: MARLFTPSESKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWRHLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIAPEYIAAVSACSMREGIVLYNNEGTPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSDIYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADILSPVKETGTLLGVVSSQAAELCGLKAGTPVVVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLIAERLGIDTYTLLEEMTSRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKATLFRALEENAAIVSACNLQQIADFSNIHPSSLVFAGGGSKGKLWSQILADVSGLPVNIPVVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTHTPAPEKHELYQDSRDKWQAVYQDQLGLVDHGLTTSLWKAPGL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_HAHCH
Sequence: MPPSAQTQPKYKRVLLKLSGEALMGEENFGIDPKVLNRMALEIGQLIGIGVQVGLVIGGGNLFRGKALQDAGMDRVTGDHMGMLATVMNALAMRDALERSNIATRVMSAIPMSGVVEHYDRRRAIRDLKEGDVVIFCAGTGNPFFTTDSAACLRGIEIDADVVLKATKVDGVYSDDPMKVADAVKYDRLTYDEVLERKLGVMDLTAICLCRDHGMPVRVFDMNKASALINIVVGMEEGTLIERG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_STRP3
Sequence: MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGCFQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NAGB_CLOBA
Sequence: MKILVCENYDKLSEKAAQIIMSQITLKSNSILGLATGSTPIGMYKKLVEMYENKMIDFSDVKTFNLDEYQNLPISNDQSYHYFMDDNLFNYINVKRENIHIPNGMANDIENECIEYDNLIKEAGGIDIQVLGIGNNAHIGFNEPTVSFEKKTYVVELEESTKIANARFFNSLDEVPSKAITMGIGSIFESKKIMLLATGENKAKAIYDTIYGKVTPEVPASILQFHDDVIVILDKKAASLLNPKDYKVV
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RL25_PSEPK
Sequence: MTEFTLNAQARTDLGKGASRRLRHSANIPAVVYGGNQDAQSLTILAKEITKLFENEAAFSHVLELNVDGAKQNVVVKALQRHPAKGFIMHADFVRVVAGQKLTAKVPVHFINEEAPVKKGGEISHVESEIEVSCEAKDLPEFIEVDLANAEIGTIIHLSDLKAPKGVEFVALAHGDDKAVANVHAPRVAPEAEGAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RS9_CERS5
Sequence: MADIKSLDDLKSVVGDAPVAEAAVTREPVRDSLGRSYATGKRKDAVARVWIKPGSGKVTVNGKPMDEYFARPVLQMILRQPFTVANVTGQFDVMATVAGGGLSGQAGAVKHGISKALQLYEPSLRAALKAAGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: GGCT_MOUSE
Sequence: MASSDCEGHAGQEGETFLYFAYGSNLLTERIHLRNPSAVFCCVARLQDFKLDFGNFQGKMSERWHGGIATIFQSPGDEVWGVVWRMNKSNISSLDEQEGVKSGVYVVIEIKVSTREGKEITCRSYLMTNYESAPPSPQYKKVICMGAKENGLPQEYQEKLKAIEPNEYKGKISDEMEDIIKKGESKLS
What is the function of this protein?
Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis.  Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.
What are the official names of this protein?
Gamma-glutamylcyclotransferase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: C99A1_SORBI
Sequence: RLISAVILAVCSLISRRKPSPGSKKKRPPGPWRLPLIGNLLHLATSQPHVALRDLAMKHGPVMYLRLGQVDAVVISSPAAAQEVLRDKDTTFASRPSLLVADIILYGSMDMSFAPYGGNWRMLRKLCMSELLNTHKVRQLAAVRDSETLSLVRKVVYAAGAGGGGRGQRGEAPVVNLGRLVLSCSMAITGRATLGKLCGDEIMSVVDVAVLYGSGFCAGDLFPSLWFVDVVTGLTRRLWTARRRLDAIFDRILAECEARQRQEEKMTGDDGFLGVLLRIRDDDGEPETGGISTTSIKAILFDMLAGGTETTSSAAEWIMSELMRKPEAMAKAQAEVRGALDGKSPEDHEGQMDKLSYTRMVVKEGLRLHPVLPLLLPRSCQETCDVGGFEVTKGTKVIVNAWALARSPERWHDPEEFRPERFADDDGSSAAVAVDYRGSQFEYIPFGSGRRMCPGNTFGLAALELMVARLLYYFDWSLPDGMRPEELDMDTVVGSTMRRRNHLHLVPSPYKETELTVGI
What are the official names of this protein?
Cytochrome P450 CYP99A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: TSA2_YEAST
Sequence: MVAEVQKQAPPFKKTAVVDGIFEEISLEKYKGKYVVLAFVPLAFSFVCPTEIVAFSDAAKKFEDQGAQVLFASTDSEYSLLAWTNLPRKDGGLGPVKVPLLADKNHSLSRDYGVLIEKEGIALRGLFIIDPKGIIRHITINDLSVGRNVNEALRLVEGFQWTDKNGTVLPCNWTPGAATIKPDVKDSKEYFKNANN
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events (PubMed:10681558, PubMed:11741925, PubMed:15210711).  Can act alternatively as peroxidase and molecular chaperone.  Oxidative stress and heat shock exposure cause a reversible shift of the protein structure from low MW species to high MW complexes, triggering a peroxidase-to-chaperone functional switch.  The chaperone function of the protein enhances resistance to heat shock (PubMed:15163410).
What are the official names of this protein?
Peroxiredoxin TSA2, Prx, Cytoplasmic thiol peroxidase 2, cTPx 2, Thiol-specific antioxidant protein 2, Thioredoxin peroxidase type Ib, TPx type Ib, Thioredoxin-dependent peroxiredoxin TSA2.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_BURVG
Sequence: MNPEHSPLGKATVYAAQYDASLLFPIPRAGAREQLGIAAALPFFGTDIWNAYELSWLNARGKPQLAVATFYVPAESPNIVESKSFKLYLGSFAQSKFDSVDAVRDVLKRDVSAACGASVSVQLVSPHDFGKLQMEELDGLSLDRLDLDTDVYEPDPSLLSAAADEAPVEETLVSDLLRSNCPVTGQPDWGSVQIHYVGPQIDHAGLLRYIISFRNHTGFHEQCVERIFLDILQACKPLKLAVYARYTRRGGLDINPFRTNYNQSMPDNARTARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1ATR_HUMAN
Sequence: MPFSVSWGILLLAGLCCLVPSSLVEDPQEDAAQKTDTSHHDQGDWEDLACQKISYNVTDLAFDLYKELADLSQTSNVLVTPTSVAMAFAMLSLGTKADTRTEILEGLNVNLTETPEAKIHECFQQVLQALSRPDTRLQLTTGSSLFVNKSMKLVDTFLEDTKKLYHSEASSINFRDTEEAKEQINNYVEKRTGRKVVDLVKHLKKDTSLALVDYISFHGKWKDKFKAEHIMVEGFHVDDKTIIRVPMINHLGRFDIHRDRELSSWVLAQHYVGNATAFFILPDPKKMWQLEEKLTYSHLENIQRAFDIRSINLHFPKLSISGTYKLKRVLRNLGITKIFSNEADLSGVSQEAPLKLSKAVHVAVLTIDEKGTEATGAPHLEEKAWSKYQTVMFNRPFLVIIKDDITNFPLFIGKVVNPTQK
What is the function of this protein?
Putative serine protease inhibitor.
What are the official names of this protein?
Alpha-1-antitrypsin-related protein, Protease inhibitor 1-like, Serpin A2.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: LOLD_DESVH
Sequence: MMTTPSTPLYRLEGVGKEYDGPGEELVILKGLDLTIEAGESVAIVGASGSGKSTLLHLLGALDTPTWGKLHFLDRDMGAMSPEEKAAFRNREIGFVFQFHHLLPEFSTVENVAMQAIISGMPHAEAYGLAREALDKVGLSGRVEHKVTTLSGGERQRAAIARAILLRPRVLLADEPTGNLDERTGDVVGRMLLDLNRELGMTLIVVTHNRELADLMGRRLELRAGELYDQHRP
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MTAB_METBF
Sequence: MAAKRYTSMAYANADEMTFGVSKYPVKAGLDLEIGAGYTIPEINYAPRPEAGASKEKLIKEYERITTDVMERMVQVGFPAIILETEHVQQMSNNPSWGAEVAHAQKTIMEKYHDEYGIKCALRHTIGDIRENREFLQLRGDKYSVFLEAFEQCAENGADLLSVESMGGKEVFDYAVLRNDIPGLLYSIGCLGSIDMELIWTDISKIAKKTGTISAGDTDCAQANTAMFIGGGLLNKNLAHTIAVIARAISAPRSLVAYEAGAVGPGKDCGYENIIVKAITGMPMTMEGKTSTCAHSDVMGNLVMQCCDCWSNESVEYHGEFGGTTVQCWSETLAYDCALMNTALETKNDKVLRDLMMLSDRYRDPQAYMLAYDNAYRVGQSIVKDGDNIYLRAKNAAIECCNIIEEGAAGKLELSRFETKALADAKAALEALPDDMDKFMDDCLTKYKSEVKVFKPENYGF
What is the function of this protein?
Methyltransferase involved in methanogenesis in the methanol pathway.  Catalyzes the methylation of the MtaC-bound cob(I)amide.
What are the official names of this protein?
Methanol--corrinoid protein co-methyltransferase, Methanol:corrinoid methyltransferase 1 subunit of 50 kDa, MT1 subunit 50 kDa.
What is the protein family that this protein belongs to?
Belongs to the MtaB family.
Protein: RUVB_LIMRD
Sequence: MENDHGILSDHPSGEEESQVEITLRPQKLREYIGQPKIKHELEVYIKAAQSREEALDHVLLYGPPGLGKTTLAMVIANEMGVNIRTTSGPAIEKPGDLVALLNELKPGDVLFVDEIHRLPKVVEEMLYSAMEDYYIDIVIGEGPTAHPVHFPLPPFTLIGATTRAGMLSAPLRDRFGIVEHMNYYTQDELTKIIFRSAKIFHTSIQDEGAHELSLRSRGTPRIANRLLKRVRDFAQVAGKQSIDSAIVKQALSLLQVDDRGLDEIDRKMLLTMINFYHGGPVGLKTIAANIGEETNTIEEMYEPYLLQIGFISRTPRGRLVTPTAYEHLGIEYPTDKN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HSLU_XANCB
Sequence: MPNIDTATMTPREIVQELDRHIVGQHDAKRAVAIALRNRWRRMQLPEELRNEVMPKNILMIGPTGVGKTEIARRLATLANAPFVKVEATRFTEVGYVGKDVEQIIRDLADTSVKLYREQAKVRVRNQAEERAEDRILDALLPRRSAGIGFDPEAARHEPSAQDNETRIKFRRMLRNGELDEREIELEVAVNASMDIMTPPGMEEMGQQLRQMFSNLGGGKSQKRKLTIKAARPLLIEEEAGKLVNEDDIRTAAIEACEQHGIVFIDEIDKVAKRGEAGSSGGDVSREGVQRDLLPLVEGSNVSTKYGTVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELTALTKADFVRILTEPKAALIKQYEALLQTEGVALTFGADAVDRLAEIAAQVNERQENIGARRLHTVLERLLDVLSYEAPDRDGQSVTVDAAYVDAQLGELVQDPDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_MARN8
Sequence: MTEATQTARTLSGKVVSNKMDKSIVVLVERQVKHPLYGKYMKRSTKIHAHDESNQCNIGDTVTIQETRPVSKTKSWALVEVTERAAKV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ARNB_SALA4
Sequence: MSDFLPFSRPAMGAEELAAVKTVLDSGWITTGPKNQELEAAFCRLTGNQYAVAVSSATAGMHIALMALGIGEGDEVITPSMTWVSTLNMIVLLGATPVMVDVDRDTLMVTPEHIEAAITPQTKAIIPVHYAGAPADLDAIYALGERYGIPVIEDAAHATGTSYKGRHIGARGTAIFSFHAIKNITCAEGGIVVTDNPQFADKLRSLKFHGLGVDAWDRQSGGRAPQAEVLAPGYKYNLPDLNAAIALAQLQKLDALNARRAAIAAQYHQAMADLPFQPLSLPSWEHIHAWHLFIIRVDEARCGITRDALMASLKTKGIGTGLHFRAAHTQKYYRERFPTLTLPDTEWNSERICSLPLFPDMTESDFDRVITALHQIAGQ
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: SYH_AGRRK
Sequence: MSDKQKKPQKLKARLPRGFVDRSASDIRAVNEMTAKIRAVYEHYGFDPMETPLLEYTDALGKFLPDSDRPNEGVFSLQDDDEQWMSLRYDLTAPLARHVAENFNEIQLPYRTYRAGYVFRNEKPGPGRFRQFMQFDADTIGAPGVQADAEMCMMMADTLEALGIKRGDYLIRVNNRKVLDGVLEAIGLGGDDKAGQRLNVLRAIDKLDKFGPEGVALLLGPGRKDESGDFTKGAGLNAEQIDKVLFFVGIKDYAESAAQLAELVAGTSKGGEGVEELNFIGSLVTSAGYQSDRIKIDPSVVRGLEYYTGPVYEAELTFDVTNEKGEKVVFGSVAGGGRYDGLVSRFMGQPVPATGFAIGVSRLMTALKNLGKLGQDEVIAPVLVTVMDGDVEAMGRYQRFTQQLRAAGIRAEMFQGNWKKFGNQLKYADRRGCPIAIIQGGDERAEGVVQLKDLIEGKRLSGEIEDNASWREARVAQETVPEADLVAKVQAILAAQAEDRKRAE
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFJ_NOSSO
Sequence: IDGNEAVAQVVYQINEVIAIYPITPSSPMAEWADAWASEGKPNIWGTVPTVVQMQSEGGVAGAVHGALQTGSLTTTFTASQGLLLMIPNMYKIAGELTPTVFHIAARSLAAQALSIFGDHSDVMATRGTGFAMLCAASVQEAHDFALISTRTTLESRIPFLHFFDGFRTSHEINKIELLTTENLQTFIPNELVIAHRSRAFTPDNSFTRGTGQNPDVYFQGEEGTVIYYIACQASLKSMDEFAQMTGRQYQLFEYHGDSTAERVIVLMGSGCETVHETVDYLNTLGEKVGVIKVRLYHPFDSQRFIAALPPTTRSIAVLDRTKEPGASGEPLYLDVVAALYEAGEQLPKVVGGRYGLSSKEFTPGMVKAVFDNLAATIPKNHFTIGINDDVSHTSLDYDPDFNI
What is the function of this protein?
Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase.
What are the official names of this protein?
Pyruvate-flavodoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
Protein: PUR5_BACVZ
Sequence: MSDAYKNAGVDIEAGYEAVKRMKKHVERTQRLGVMGSLGGFGGMFDLSELPYQKPVLISGTDGVGTKLKLAFSMDKHDTIGVDAVAMCVNDVLAQGAEPLFFLDYLAVGKADPVKIEQIVQGVADGCEQSGSALIGGETAEMPGLYTADEYDIAGFSVGVAEKDEIVTGEHIEEGHLLIGLTSSGLHSNGFSLVRKVLLDDGGLDLDTVYEPFARPLGEELLEPTRIYVKPVLKAVKSGKVDGMAHVTGGGFIENIPRMLPDGLSAEIDHGSWPIPPIFPFLQEHGKLKEEEMFNVFNMGIGFVLAVKEEDLTGVIDTLEAQGEKAYLIGRVKRGEGISFGGAALS
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KKA5_STRFR
Sequence: MDDSTLRRKYPHHEWHAVNEGDSGAFVYQLTGGPEPQPELYAKIAPRAPENSAFDLSGEADRLEWLHRHGIPVPRVVERGADDTAAWLVTEAVPGVAAAEEWPEHQRFAVVEAMAELARALHELPVEDCPSDRRLDAAVAEARRNVAEGLVDLDDLQEERAGWTGDQLLAELDRTRPEKEDLVVCHGDLCPNNVLLDPGTCRVTGVIDVGRLGVADRHADIALAARELEIDEDPWFGPAYAERFLERYGAHRVDKEKLAFYQLLDEFF
What is the function of this protein?
Resistance to kanamycin and structurally-related aminoglycosides, including amikacin.
What are the official names of this protein?
Aminoglycoside 3'-phosphotransferase, APH(3')V, Kanamycin kinase, type V, Neomycin-kanamycin phosphotransferase type V.
What is the protein family that this protein belongs to?
Belongs to the aminoglycoside phosphotransferase family.
Protein: NUDT3_BOVIN
Sequence: MMKLKSNQTRTYDGDGYKKRAACLCFRSESEEEVLLVSSSRHPDRWIVPGGGMEPEEEPGTAAVREVCEEAGVKGTLGRLVGIFENQERKHRTYVYVLIVTEVLEDWEDSVSIGRKREWFKIEDAINVLQCHKPVQASYFETLRQGYSANNGTPLVAPTYSVSAQSSMPGIR
What is the function of this protein?
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction (By similarity).  InsP6 (inositol hexakisphosphate) is not a substrate (By similarity).  Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with diadenosine 5',5'''-P1,P6-hexaphosphate (Ap6A) and diadenosine 5',5'''- P1,P5-pentaphosphate (Ap5A) being the preferred substrates (By similarity).  The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A (By similarity).  Also able to hydrolyze 5- phosphoribose 1-diphosphate (By similarity).  Acts as a decapping enzyme that modulates the stability of a subset of mRNAs implicated in cell motility (By similarity).
What are the official names of this protein?
Diphosphoinositol polyphosphate phosphohydrolase 1, DIPP-1, Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1, Nucleoside diphosphate-linked moiety X motif 3, Nudix motif 3.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. DIPP subfamily.
What are the subcellular locations of this protein?
Cytoplasm.