PharMolix/UniProtQA huggingface dataset:
Protein: MNMG_STRP8
Sequence: MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDMLAFMPCNPSIGGSAKGIVVREIDALGGEMSKNIDKTYIQMKMLNTGKGPAVRALRAQADKSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTALRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTEIQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGLEKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGINAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMRLTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTDAMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMKRMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEGNGKAHRKY
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPAR_CHLAE
Sequence: MGHPLLLPLLLLLHTCVPASWGLRCMQCKSNGDCRVEECALGQDLCRTTIVRMWEEGEELELVEKSCTHSEKTNRTMSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTFSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDMVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGHQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTYEPKNQSYMVRGCVTASMCQRAHLGDAFSMNHINVFCCTESGCNHPDLDVQYRKGAAPQPGPAHLSLTITLLMTARLWGGTLLWT
What is the function of this protein?
Acts as a receptor for urokinase plasminogen activator.  Plays a role in localizing and promoting plasmin formation.  Mediates the proteolysis-independent signal transduction activation effects of U-PA.  It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity).
What are the official names of this protein?
Urokinase plasminogen activator surface receptor, U-PAR, uPAR.
What are the subcellular locations of this protein?
Cell membrane. Cell projection, invadopodium membrane. Cell membrane; Lipid-anchor, GPI-anchor. Note=Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin-dependent manner.
Protein: RL16_STAA1
Sequence: MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRLASHKLPVKTKFVKREELGGETNES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RS7_GEOSL
Sequence: MPRRREVAKRVILPDPKFNDRVVAKLVSVIMLDGKKSTAERALYGALDIVSQKAGEEPVKVLKKCLDNIKPMLGVKSRRVGGSTYQVPVEVRADRRVSLAMRWLVRYANERSEKTITDKLAGEILDAYNNRGAAVKKREDTHRMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ARGJ_HALH5
Sequence: MNVINETANVLKLETGSVTSAKGFSAVGIHTGVKRKRKDLGAIVCEVPASSAAVYTLNKVQAAPLKVTQESIAVEGKLQAMIVNSGIANACTGKRGLDDAYTMRAVGAETFHIPEHYVAVTSTGVIGEFLPMDVITNGIRQLKPEATIEGAHAFNEAILTTDTVEKHTCYQTIVNGKTVTVGGVAKGSGMIHPNMATMLSFVTTDANIDHGHLQGALSAITNETFNRITVDGDTSTNDMVVVMASGLAENEALTPEHPDWANFYKALQLACEDLAKQIARDGEGATKLIEVEVTGAANDQEAGMVAKQIVGSDLVKTAIYGADANWGRIICAIGYSGCEVNQETIDIAIGPIVTLKQSEPTGFSEEEATAYLKEADPVKISVNLHIGNGTGKAWGCDLTYDYVRINAGYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
Protein: SYH_CORGL
Sequence: MSQNKSKSEKLQSFAAPKGVPDYAPPKSAAFLAVRDAFVNQAHKAGFEHIELPIFEDTGLFARGVGESTDVVSKEMYTFADRGERSVTLRPEGTAGVMRAVIEHSLDRGQLPVKLNYAGPFFRYERPQAGRYRQLQQVGVEAIGVDDPALDAEIIALADRSYRSLGLQDFRLELTSLGDRHCRPEYRQKLQDFLFALPLDEETRKRAEINPLRVLDDKRPEVQEMTADAPLMLDHLDAECREHFETVTGLLDDMGVPYVINPRMVRGLDYYTKTCFEFVHDGLGAQSGIGGGGRYDGLMAQLGGQDLSGIGYGLGVDRTMLALEAEGVTVGAERRVDVYGVPLGKDAKKALAGIVNTLRAAGISTDMSYGDRGLKGAMKGADRSNALYTLVLGEQELENNTIAVKDMRAHEQHDVALDEVVAFLQGKLI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_STRP7
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RL22_SHELP
Sequence: MEVLAKHRFARTSPQKCRLVADQIRGLPVAKALEILTFSPKKAAVLVKKVLDSAIANAEHNEGADIDELKVGKVFVDEGPTMKRIMPRAKGRADRIIKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: LOLB_NEIMA
Sequence: MKHTVSASVILLLTACAQLPQNNENLWQPSEHTRSFTAEGRLAVKAEGKGSYANFDWTYQPPVETININTPLGSTLGQLCQDRDGALAVDGKGNVYQAESAEELSRQLVGFKLPIQYLHIWADGRPVAGAPYRILPDGILEQYGWTVGRTADSGGQVRTLQLNNGNLNIRLVFTEIGMPSETETQEQCAARIQ
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: TBC17_MOUSE
Sequence: MEGSSYRVVFEKGGVYLHTSARKHQDPDSLIAGVIRVVEKDSDVFLHWAPVEEAGDPTQILFKKDPSRGEPSTSEEEPTFDPGYEPDWAVISTVRPQPHLAEPRKGAEPSSSRSSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASSPNLPPLPDDEPEPGFEVISCVELGQRPTVERAPPVTEEEWNRYVGPEGRLQNVPELKNRIFSGGLSPGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLSLLHDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEILGLAQPEEPSSPSPPVSPMPLSPTRAPLPPPLPEEVIPQPDSSLEILPEDEDGA
What is the function of this protein?
Probable GTPase-activating protein that inhibits RAB8A/B function.  Reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC) and inhibits Rab8-mediated endocytic trafficking, such as that of transferrin receptor (TfR).  Involved in regulation of autophagy.
What are the official names of this protein?
TBC1 domain family member 17.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome.
Protein: PROB_AGRVS
Sequence: MSAPLASLSHYKRIVIKIGSALLVDRGAGLKHAWLDAVCDDIAALRAKGVEVLVVSSGAIALGRTVLNLPGGALKLEESQAAAAVGQIALARHWSESLSRSSIVAGQILLTLGDTEERRRYLNARATISQLLKLGAVPIINENDTVATTEIRYGDNDRLAARVATMTGADLLILLSDIDGLYTAPPHLDPEAKLLPVIAEITPEIEAMAGGAASELSRGGMRTKIDAGKIATSAGCAMIITSGKLLNPLRGIDEGAAHSWFAPSAMPVTARKTWIAGQLQPAGILSVDAGAETALRAGKSLLPAGVREVSGHFHRGDTISVVGLEGREIARGLAGYDADEARRIAGHKSAEIEALLGYAGRSAMIHRDDLVMTEQTGRKAGKSTKKKDEAHA
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKT3_AUSSU
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPEFCELPADSGSCKGNFQAFYYNPVQHQCLEFIYGGCDGNANNFKTIDECKRTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor superbin-3.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: UCRIB_NOSS1
Sequence: MDDTLNQANPSMSRRQLLNFFTGAIVATTASAAIYPATKFFMPPAESTDAEGGILAQDKIGHPIPASQILAQASGTRALIAGLAGEPTYLTVREDGTLDPMGIVNNCTHLGCTFPWNPVDQQFQCPCHGSRYDAQGSVERGPANRPLKLVQVQVKDDYIWISPWQETDPRTGEKPWWV
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit 2, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein 2, ISP 2, RISP 2, Rieske iron-sulfur protein 2.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: SYGB_TRIEI
Sequence: MIVTFLLEIGTEELPANFVYEAIQQWQELIPMTLKEAFLTNDSVNVYATPRRLAVVIDALPTKQPDREEEIKGPPAKAAFKDGKPTKAAEGFSKKQGVQLNDLQICTTEKGDFVFVNKKIQGKPTAAILTELIPKWIDKLEGKRFMRWADGELKFPRPIRWLVALLDDEILPINLDNGSQKITSDRFSYGHRVLHPKLIEISQAKNYVEVLKKAYIEVDYKQRKSKIEQQIKTAAEEIKGKAEISEELLAEVTNLVEWPTVVIGKFDEEFLILPGEVTTTVMETHQRYFPVFKSTKTFKDMELLPYFITISNGDPEKSEIIAIGNERVIKARLADGQFFYKTDLAKPLESYLPELETVTFQAKLGSMREKVKRIVSIAKLIAGQLQITQEESKNIERAALLCKADLVTQMVYEFPELQGVMGEKYARAAGETEAVATAIFEHYLPRGAGDILPKTISGQVISLADRLDTLVSIFGLGMLPTGSADPFALRRAANGVVNISWSANLPLNLHQLLEEIATNFFKTYSQTNSDLLAQLSNFLLQRIKTILLEEKNIDYDLVNAVLGDNDAEYKERGLKDLLDVRNRAIFLQNIRQNGMLGKIYETINRSTRLAAQGELDKIQLKPLKVIDSKLFKSESELAFYNALVELVPQTEISQKTRNYQQLVDALLKIAPTVSNFFDGPDSVLVIDPDPKIKKNRLNLLGLLRNNARVLADFGQIVKN
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GME65_PESMI
Sequence: MLFSFLQETAYAVYGLWASFYPSLYQRPLSSSTRHLDHGPDNRGYWKDGFSIKTDYEVEIPEGKLVEYFFTISEAEIAPDGYLTNVTLVNDQFPGPKIEADWGDTIRVTVYNNLTNSNGTSFHWHGIRQFQTNYLDGVPGVTQCPSKPGDTQVYEFRAMQYGTGWYHSHYSLQYTNGARGPVVIHGPSSANYDIDVEPLLITDWYHADAFSYFHEEITDHAHIPTGTLLNGKGVYECDPTKDSRCVSPPGERHTIQFEPGKKHKLRIISSASLATYKFWIDGHNFTVISTDFVPIEPYVTDILIVGVAQRYEVIVEANATFEHGSNFWIHGTHCDDMIPVPWDTRIGIIQYDAEDNSDPYTPPLETTHPGYGCRDPPPTSLVPIVPRQVGNNVNGFSPADYLEIGLQSWPNISDPDSTIRKWVLANRTQYVDWREPSLRKLVHDNGKTNFTQDEAPIVLDYETGEWVYFVIEGNFTMRDPINDPRPIPRSVHPIHLHGHDFAILAQGDGYFSKDVVPNLDNPARRDTVNLPIGGYVWIAFQINNPGTWLMHCHIAWHASAGLSLQFIEQPSKIKPLVEASGILPEMESRCKDWTEHYNKVNIPLGLVQEDSGI
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of dibenzodioxocinones such as pestalotiollide B, a novel class of inhibitors against cholesterol ester transfer protein (CEPT) (PubMed:31474098).  The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS pks8/GME11356.  Pks8/GME11356 lacks a thioesterase (TE) domain, which is important to the cyclizing of the third ring of atrochrysone carboxylic acid, and the esterase GME11355 might play the role of TE and catalyzes the cyclization reaction of the C ring.  The lactamase-like protein GME11357 (or other beta-lactamases in Pestalotiopsis microspora) probably hydrolyzes the thioester bond between the ACP of pks8/GME11356 and the intermediate to release atrochrysone carboxylic acid, which is spontaneously dehydrates to form endocrocin anthrone.  Endocrocin anthrone is further converted to emodin via the endocrocin intermediate.  Emodin is then oxidized by several enzymes such as the Baeyer-Villiger oxidase GME11358, the oxidoreductase GME11367, the short chain dehydrogenase/reductase GME11373, as well as by other oxidoreductases from the cluster, to modify the A and C rings and open the B ring, and finally yield monodictyphenone.  The prenyltransferase GME11375 may catalyze the addition reaction between the C5 side chains and the carbon bone of dibenzodioxocinones.  The remaining biochemical reactions to the final product dibenzodioxocinones should be methylation catalyzed by methyltransferase GME11366 and reduction and lactonization reaction catalyzed by a series of oxidordeuctases (Probable).
What are the official names of this protein?
Oxidoreductase GME11365, Dibenzodioxocinones biosynthesis cluster protein GME11365.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: RL31_SYNFM
Sequence: MKEGIHPVYHETVIRCACGAEIPTGSTKKEIRVEICSKCHPFYTGKQKLVDSAGRIERFRRKYEKFQKKETPESTE
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: LOLD_GRABC
Sequence: MSDYPSCALRLEQVARRYRSGDQELVVLDHADLELRPGEIVALVAPSGTGKSTLLHLAGLLEKPDEGRVWIGSHDAGGLSDTARTALRRDHLGFVYQFHHLLGEFSALENVVLPQMIAGRTRRQAEQHALTLLSAFGLQHRASHLPGMLSGGEQQRVAIARALANGPAVLLADEPTGNLDIHTAETVFSALLSAVRNQNVAALIATHNPDLAGRMDRQVTIREGQIVPA
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS19_ORITB
Sequence: MARSIWKGPFVRESLIKKVNKLIESGKSSVIKTWSRESAIIPLFVRFVFAVHNGNKFIPVVITEEMVGRKLGEFAPTRTFYGHAADRKVKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CXD4_HUMAN
Sequence: MEGVDLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPRPFGERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGPPTSPSIRKQSGASGHAEGRRTDEEGGREEEGAPAPPGARAGGEGAGSPRRTSRVSGHTKIPDEDESEVTSSASEKLGRQPRGRPHREAAQDPRGSGSEEQPSAAPSRLAAPPSCSSLQPPDPPASSSGAPHLRARKSEWV
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction delta-4 protein, Connexin-40.1, Cx40.1.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Delta-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: Y5342_EMENI
Sequence: MVRVSRGCQSCVDAKLQSTPSPSPSKSPSPTESPEQCLQKRQSGEQVVLPSRPFPRTSPRAEYRPVPLLALDGYINPSLTVTAVNSQQAQVFTNYVLASFPCFFRCTETRVPVNWVEYVDQRGSSMNSCFDWAVRACTSAYLGSLHDDQRYLVASRSLYHRALRGLGNLLSSEKTAKSDEVLASAIVLAIFEKHNCSSPDAWLRHAAGIRTLMKLRGPKAHLEGFGRAMYIVYRNFLITAALVEGEACFLEEPEWQALNEEIAASDAKLPTSSLYTDVVERGFLSVIKIPGLVKRTRELQCLSSKKRAEVQPALLQDVQATRAGLRGIYTEFGVAVSMLRSGQDENDTFVGPVPNFFFEGYSSLFARGVRLGLLILNYLIVIMDPKQRATIDSENFMLLNDMTRSQRSTHPALEFKLPLTPPKSPGRPGLVVRSLITEETREPPTTDWMDRITSTMGLEAVHVSLVG
What is the function of this protein?
Involved in osmoadaptation.
What are the official names of this protein?
Uncharacterized protein AN5342.
Protein: SUCC_SALPB
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVKSKEEIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIGKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: SYFB_THEMA
Sequence: MRVPESWLREFVDLDWDIEQIAERLTFSGTSVEDILRPFNVSGEIITARVIERFDHPASEKLIVCKVDTGKRIYTVITADKTVNEGDYVILALEGATLNNGLKIEPREFKGVISEGMLCSLEELGLEEKSDRVYRFPDPVELGVNVVEEYGLNERVLDIEITPNRPDCLSIIGVARELSALSGRPLNKPQPDVSFVDEDVQFDVEIEDVEGCPRYSARIMKGVTVKDSPLWMKARLVAAGVRSLNNVVDATNYVMIELGHPVHAFDLNRLKNKRIVVKSAKGGERVLLLDEKEYELKGGEVLITDGENVLALGGIMGGMESGVYDDTRDLVLEVAYFDPVRIRKAAKALGISSESSYRFERGVDPNDVELVSLRLAELIQKLAGGYVLRKFWDVYPRKIEPKKVMLRKARIEKILGTKVEEPGDILRRLEFQVEDRGDSYEVLVPTFRPDVEREIDLIEEIGRIYGYEKVESKVISVPAVNRGWGEKQLFRREISQFMKGMGFDEVVTFSFVDSQKVKKWPLVDREPIALSNPIASDMDVMRTSQFYSLIQVLAENFKRQNRDLKLFEIGKIYFKENGNFREIETLSAMSCGLENPGDYTDKRSVSFYTIKGVLDELFFRLGVNVVYRAAEIPGLFPTRSARIYVENREIGFIGMVDPKLLDEYDVKEDTYFFEIDMELLRKYASKRPAYRPTPRFPAVRRDISFLLPKGFESVKIIELFKKSGGDLVEEVGVFDIYEGKGIPENMVSVTLYVVFRHPERTLTDEEVNKIFEEMVQKAEREFGIRRRF
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_PSEPK
Sequence: MEIGLREWLILIGIIVIAGILFDGWRRMRGGKGKLKFRLDRSYSNLPDEEGGSAEVLGPSRVLDTHKEPELDESDLPSLSASARDREREPKPVKASKRGKRASAAADVHQGDLNLSAEPREPDLFSDSDDDFAADNNRSSGAAPASNSVKELPPAEEVLVISVISRDEGGFKGPALLQNILESGLRFGEMDIFHRHESMAGHGEVLFSMANAVKPGVFDLDDIDHFSTRAVSFFLGLPGPRHPKQAFDVMVAAARKLAHELNGELKDDQRSVLTAQTIEHYRQRIVEFERRALTQKR
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: ACTY_MOUSE
Sequence: MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGADFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF
What is the function of this protein?
Component of a multi-subunit complex involved in microtubule based vesicle motility.  It is associated with the centrosome (By similarity).
What are the official names of this protein?
Beta-centractin, Actin-related protein 1B, ARP1B.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: SPO14_ORYSJ
Sequence: MDDSTDDDSYHPRKHYAYDRQVSSSRWRTSREYIRGPGPETHTTESAQDGQDPPAGVYSYGYFSGSGNDPQVQGHFVPEIQKYNPYVIFKGEQLPVPIWELPEEKVQDFHDRYFIAKDKSRVEARKTLNRLLEGNINTIERGHGYKFNIPKYTDNMEFNEEVKVSLAKAGKTISRSFCNANQREVASRTGYTIDLIERTLGAGLNISKRTVLYTNKDLFGDQSKSDQAINDICALTNIRRGSLGIIAAEKGIVVGNIFLELTNGKSISCSIGVQIPHRLDQIKDVCVEIGSRNIEYILVVEKHTMLNYLLEMDYHTNNNCIILTGCGMPTLQTRDFLRFLKQRTGLPVFGLCDPDPEGISILATYARGSCNSAYDNFNISVPSICWVGLSSSDMIKLNLSETNYSRLSREDKTMLKNLWQDDLSDVWKRRIEEMISFDKKASFEAIHSLGFDYFATNLLPDMINKVREGYVQVQEKKEPQDTEASED
What is the function of this protein?
Required for meiotic recombination.  Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.  Possesses double-stranded DNA cleavage activity in vitro.
What are the official names of this protein?
Meiotic recombination protein SPO11-4, OsSPO11-4, OsSPO11D.
What is the protein family that this protein belongs to?
Belongs to the TOP6A family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_SYNPW
Sequence: MSLKQRYRETIQPKLLKDLSLSNVHEVPKVVKVTVNRGLGEAAQNAKSLEASVNELAQITGQKVVVTRAKKAIAGFKIRQGMPIGCAVTLRGERMYAFLERLINLALPRIRDFRGVSPKSFDGRGNYTLGVREQIIFPEISFDKIDAIRGMDITIVTTARTDEEGRALLREMGMPFRSN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: YIO1_YEAST
Sequence: MFPLRAVLEPCLKNVIIPIVGMVKDSISTTSKLLAESRPPLSSNFHFSYENLFSYSLLSHPVVIDTATATITRRTEQLLNRKIISSSKRFPASNIYVYQEAFTYHDTASDFIIADSYYITTPSSSGHAL
What are the official names of this protein?
Putative uncharacterized protein YIL141W.
Protein: COAX_LEGPC
Sequence: MILCIDVGNSHIYGGVFDGDEIKLRFRHTSKVSTSDELGIFLKSVLRENNCSPETIRKIAICSVVPQVDYSLRSACVKYFSIDPFLLQAGVKTGLNIKYRNPVEVGADRIANAIAATHSFPNQNIIVIDFGTATTFCAISHKKAYLGGAILPGLRLSADALSKNTAKLPSVEIIKTESVVGRSTIESIQSGVYYGVLGACKELIQRIHHEAFNGDKILILATGGFASLFDKQGLYDHLVPDLVLQGIRLAAMMNTA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.