PharMolix/UniProtQA huggingface dataset:
Protein: XRCC2_MOUSE
Sequence: MCSDFRRAESGTELLARLEGRSSLKELEPNLFADEDSPVHGDIFEFHGPEGTGKTEMLYHLTARCILPKSEGGLQIEVLFIDTDYHFDMLRLVTVLEHRLSQSSEEAMKLCLARLFLAYCSSSMQLLLTLHSLEALLCSRPSLCLLIVDSLSSFYWIDRVSGGESVALQESTLQKCSQLLERLVTEYRLLLFATTQSLMQKGSDSADGPSSSKHPCDGDMGYRAYLCKAWQRVVKHRVIFSRDDEAKSSRFSLVSRHLKSNSLKKHSFMVRESGVEFC
What is the function of this protein?
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.  Part of the RAD51 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway.  Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment.  BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks.  The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA (By similarity).
What are the official names of this protein?
DNA repair protein XRCC2, X-ray repair cross-complementing protein 2.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RAD51 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMA_DEIRA
Sequence: MTPNPMTNDLPDPAAAPDSAPLYSPARVRALLAAHGLKPTKSLGQNFLIDGNILRAIAEAGGAAPGENVLEIGPGLGVLTREVASRGARVTALEKDERLRPVLAETLAGLDVNVIWGDALDFDYAALPAGTRVIANLPYYITGLLLTRFMQAPGVVSATVLVQKEVAQRLVAQPGQDNYGFLSAVAALYGSVKHVRDVPKGAFFPAPDVTSSVVRLDFDRTRPQPDPAFVSFVDNALRYRRKTLRNNLRMMGHSGEAIDAALSDLGLRPDVRAEDVPLSGLRAVAAALGVVR
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QOX1_STAEQ
Sequence: MNFPWDQLLVKGNWMIISAQIAAPFLVIGLIAVISYFKLWKYLYKEWFTSVDHKKIGIMYLISAVLMFVRGGIDALMLRTQLTIPDNKFLEANHYNEVFTTHGVIMIIFMAMPFIFGLWNVVIPLQLGARDVAFPVMNNVSFWLFFAGMILFNLSFIVGGSPAAGWTNYAPLAGEFSPGPGVNYYLIAIQISGIGSLMTGINFFVTILRCKTPTMKFMQMPMFSVTTFITTLIVILAFPVFTVALALMTADRIFGTQFFTVANGGMPMLWANFFWVWGHPEVYIVILPAFGMYSEIIPTFARKRLFGHQSMIWATAGIAFLSFLVWVHHFFTMGNGALINSFFSISTMLIGVPTGVKLFNWLLTLYKGRITFESPMLFSLAFIPNFLLGGVTGVMLAMASADYQYHNTYFLVAHFHYTLVTGVVFACLAGLIFWYPKMMGYKLNETLNKWCFWFFMIGFNVCFLPQFILGLDGMPRRLYTYMPSDGWWLLNFISTIGAVLMAIGFLFLVASIVYSHIKAPREATGDNWDGLGRTLEWSTASAIPPKYNFAITPDWNDYDTFVDMKEHGRHYLDNHNYKDIHMPNNTPVGFWMGIFMTIGGFFLIFESIVPALICLAGIFITMIWRSFQIDHGYHIPASEVAETEARLREARIKEREAVSHES
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
What are the official names of this protein?
Probable quinol oxidase subunit 1, Quinol oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPE_AERHH
Sequence: MSDVIALAKDLIRRPSVTPLDEGCQTLMAERLAKLGFVIEPMVFEDTTNLWARRGSEGPLFCFAGHTDVVPAGPLDKWHTPPFEPTIQDGVLYGRGAADMKGSLAAMVVAVERFVAEHPDHSGSIAFLITSDEEGPFINGTTRVIDTLEARHEKITWCIVGEPSSTTVVGDVVKNGRRGSITGDLLVRGVQGHVAYPHLADNPIHKAAPALAELAATVWDEGNAYFPPTSFQIANISAGTGASNVIPGELHVQFNFRFSTELTDLDIRERVEALLDRHGLDYQLDWTLSGQPFLTDTGKLLAAAVSAIEAVNGQQPALLTTGGTSDGRFIAPTGAEVIELGPVNATIHKVNECVKADDLDLLADMYQGVLARLLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: UL62_HCMVA
Sequence: AEKSSSKTSQKKAQKSYRAIFLPAWSKNAPRLSTPFSLVRHVGAQNGMTSERTVEKVTKMAPVGVRSNGVLQFRGHLNRERWGILRDTVLSDGGEDRALPSYCRLDFFRPSAPVSVHGFSTAKSEKGKKGGACSLPGSRTSRHAGWDGRGLLGPCRDPPRGFTVFRTPPGKGGKRVEPTGTCVRAGEKTRLGLNQRWVTCRAHRVGTVIVEGRTDDN
What are the official names of this protein?
Uncharacterized protein UL62.
Protein: MU123_SCHPO
Sequence: MERLATRSSHDDPYSRSSLPTSNAINSNHESNGSTFSYVQSLRRAKATVWSDIGRVAPLHSSPSIKSSSQNGKSSSKGLGGMRSRVFSSQHHGVYHTRPASLHSRTMAPQHTILTPRLSATEGKDDDEDELVISTSNTAPTYISMIESSRASSTHSGTAPSIMGMSIHSRADSRAETTQSDGFESRSGSPTHDIQSYLVNRRSSSSESSDEDSAEEGMKRLVITNMGDNDEFDSD
What is the function of this protein?
Involved in sporulation and has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 123 protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PURT_METCA
Sequence: MRIGTPNSPSAVRVMLLGSGELGKEVAISLQRYGVEVIAVDRYAGAPAQQVAHRSHVVDMTDPGAIHRLVEFERPHFVVPEIEAIATDALVEIERAGLAEVVPNARAVQLTMNREGIRRLAAEKLGLPTSPYAFADSCAALAEAAAKIGFPCFVKPVMSSSGKGQSLLESPSDVQAAWDHARQGGRVGASRVIVEGRIDFDFEITLLTVRAPVSGGDAGIAFCEPVGHRQQAGDYVESWQPQSLNPKARERAEAIARTVVDALGGRGLFGVELFVRGDEVWFSEVSPRPHDTGMVTMVSQAQNEFELHVRAILGLPVDSSLRRPGASAVIYGGVAAEGIAFEGLERALAVPESEVRLFGKPEAHPRRRMGVALAAADTVEEARRRAVLAASRVRPVKIPA
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: MNMA_STRPQ
Sequence: MTDNSKICVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWHDTDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLSQEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQKGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQGFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVRVHVRGDKAEVVFAEPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX33C_TRILK
Sequence: MKLFMVLVASFAFAVALPSKKREETAAENELTGDLQEAAQPMIYAVAFPEIRASCVIGWKQQGATCQRDCECCGVAATCITGDSSTGFCGYHQTPNALGQGILYTADTIKNGFSAIFCAG
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
Toxin ICK-24.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_CHLT3
Sequence: MAKEKASSQEQEQKVKDEKLKQLNLAVESLEKQFGKGAIMRLGDDAVVQVPVVSTGSISLDYALGVGGLPKGRIVEIYGPESSGKTTLALHAIAEAQKAGGIAAFVDAEHAFDQSYARKLGIDIKSLLISQPESGEQALSITETLVRSGAVDIIVVDSVAALVPQAELEGEMGDSQMGLQARLMSQALRKLTGAISKSNCVAIFINQLRDKIGVMYGSPETTTGGKALKFYASVRLDIRKIAQIKDGTEIVGNRTKVKVVKNKVAPPFKTVEFDIIYGEGVSRIGELIDLAVELGIVKKAGAWFSYENDKLGQGRETVKTLLKADEALFNKIYAQVKEQMVGLKLEGSSDDDSSSDS
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INMT_MOUSE
Sequence: MEGKVYIGGEDYEKEFTPKDYLTTYYSFHSGPVAEQEIVKFSLQNLYQTFSTGGVGGDVLIDIGSGPTIYQLLSACEVFREIIVTDYTPQNLQELQKWLKKEPGAYDWSSIVQHACELEGDRSRWQEKEAKLRRTVTRVLRCDVTKTPPLGSAQVPLADCVLTFLAMECACPDIDTYRAALRRLAGLLKPGGHLVTLVTLRFQHYMVGPKKFSGVYLEKEVVEKAIQDAGCQVLKCNCVSLSYSEAYCSHDGLCFVVARKGPSA
What is the function of this protein?
Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity).  Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide.  Plays an important role in the detoxification of selenium compounds.
What are the official names of this protein?
Indolethylamine N-methyltransferase, Indolamine N-methyltransferase, Aromatic alkylamine N-methyltransferase, Amine N-methyltransferase, Arylamine N-methyltransferase, Thioether S-methyltransferase, TEMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.
Protein: DNJ5G_HUMAN
Sequence: MSTVKEAAHRLSKSEMSLYAVLDLKKGASPEDFKKSYSHSALLPHPPFEYHLGRKLALRYHPDKNPGNAQAAEIFKEINAAHAILSDSKKRKIYDQHGSLGIYLYDHFGEEGVRYYFILNSCWFKTLVILCTLLTCCCFCCCCCFCCGALKPPPEQDSGRKYQQNVQSQPPRSGAKCDFRSEENSEDDF
What are the official names of this protein?
DnaJ homolog subfamily C member 5G, Cysteine string protein-gamma, CSP-gamma.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: RMLD_SHIFL
Sequence: MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPEGVAETVKKIRPDVIVNAAAHTAVDKAESEPNFAQLLNATCVEAIAKAANEVGAWVIHYSTDYVFPGNGDTPWLETDATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYAGKGNNFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVAANKPEVAGLYHLVAGGTTTWHDYAALVFEEARRAGINLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNELFTTTAI
What is the function of this protein?
Involved in the biosynthesis of the dTDP-L-rhamnose which is an important component of lipopolysaccharide (LPS) (PubMed:8170390).  Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose (By similarity).  RmlD uses NADH and NADPH nearly equally well (By similarity).
What are the official names of this protein?
dTDP-4-dehydrorhamnose reductase, dTDP-4-keto-L-rhamnose reductase, dTDP-6-deoxy-L-lyxo-4-hexulose reductase, dTDP-6-deoxy-L-mannose dehydrogenase, dTDP-L-rhamnose synthase.
What is the protein family that this protein belongs to?
Belongs to the dTDP-4-dehydrorhamnose reductase family.
Protein: VA5_POLAN
Sequence: SSQGVDYCKIKCPSGIHTVCQYGESTKPSKNCAGKVIKSVGPTEEEKKLIVSEHNRFRQKVAQGLETRGNPGPQPAASDMNDLVWNDELAHIAQVWASQCQFLVHDKCRNTAKYPVGQNIAYAGGSNLPDVVSLIKLWENEVKDFNYNTGITKQNFAKIGHYTQMVWGKTKEIGCGSLKYMENNMQNHYLICNYGPAGNYLGQLPYTKK
What are the official names of this protein?
Venom allergen 5, Allergen Pol a V, Antigen 5, Ag5, Cysteine-rich venom protein, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family. Venom allergen 5-like subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PQQE_BRADU
Sequence: MLEKQRSTAETFGIPLAVLLEITHRCPLQCPYCSNPVELDRSGKELTTDEWKKVLSELAEIGVLQVHFSGGEPTARKDLVELVKHASDVGLYTNLITSAVLLTRERLSELADAGLCHVQISFQGVEEGLADRVAGYRNAHRKKLEVAKWTRELDLPLTVNAVMHRQNLHQLPDIIQMSIDLDADRLEVANVQYYGWALKNRAALMPTVAQLDECTRLVEEARERLKGRLSIDYVVPDYYALRPKKCMGGWGRQFFNISPAGKVLPCHAAESITGLDFESVRSNHSIAWIWQNSEAFNRYRGTGWMKEPCKSCEFREIDFGGCRCQAFALTGDAANTDPACALSPLHETIFKQAEREAEGETNRFLYRNFAGGTLEPENDA
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: FACOS_MOUSE
Sequence: MAGYQLWSPWTPLDESFQWLRHTTPTPSSKHPFRASPCFPHTPSDLEVQLCLQEVTLVLDRPLVEPGESPKLPCHKSELRAVSNKKGVVRKPQPVRLSGVDSVFGRVITAQPPKWTGTFRVSDKSAFCKIISREHQWPTGLKEPQVQMTVTMCKQMLRSILLLYATYKKCTFALQHSK
What are the official names of this protein?
FANCD2 opposite strand protein, Fanconi anemia group D2 protein opposite strand transcript protein.
Protein: NU4LM_MUNFE
Sequence: MSLVYMNIMTAFMVSLAGLLMYRSHLMSSLLCLEGMMLSLFVLATLTILNSHFTLASMMPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SERC_RHOOB
Sequence: MTSTPIIPADLLPADGRFGCGPSKVRPEQLQSLVEVGSSVFGTSHRQKPVKDVVASVRSGLADLFSLPEGYEVVLGNGGTTAFWDAAAFGLIREKSLHLTNGEFSSKFASVAKNNPFIGDPIVVSADPGSAPEPVSDPSVDLIGWAHNETSTGVAIPVSRPAGSENALIAIDATSGAGGLPVNVADADVYYFAPQKCFAADGGLWIALMSPKALERVAEIKDSGRWTPDFLSLPIAVDNSSKDQTYNTPAVATLLLLANQIDWLNGKGGLDWATSRTADSSSRLYQWAEASEYATPFVTDPAHRSQVVGTIDFDDKIDAAQVAKILRANGVVDTEPYRKLGRNQLRVGMFPAIDPEDVSQLTKSIDWVVSQLG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_ACIB3
Sequence: MAKIIGIDLGTTNSCVAVLEGDKVKVIENAEGARTTPSIIAYKDGEILVGQSAKRQAVTNPKNTLFAIKRLIGRRYEDQAVQKDIGLVPYKIIKADNGDAWVEVNDKKLAPQQISAEILKKMKKTAEDYLGETVTEAVITVPAYFNDAQRQATKDAGKIAGLDVKRIINEPTAAALAFGMDKKEGDRKVAVYDLGGGTFDVSIIEIADLDGDQQIEVLSTNGDTFLGGEDFDNALIEYLVEEFKKEQNVNLKNDPLALQRLKEAAEKAKIELSSSNATEINLPYITADATGPKHLVINVTRAKLEGLVADLVARTIEPCKIALKDAGLSTSDISDVILVGGQSRMPLVQQKVQEFFGREPRKDVNPDEAVAIGAAIQGAVLSGDKNDVLLLDVTPLTLGIETMGGVLTPIIEKNTTIPAKKSQVFSTAADNQPAVDISVYQGERKMAQQNKLLGNFQLGDIPPAPRGVPQIEVSFDINADGILKVSAKDKSTGKEQSIQIKANSGLSDAEIEAMIKDAEANAEEDRKFEELAKARNEADALISSSNKAVKDLGDKVTEDEKTAVNTAVSELEAATKENDVEVIKAKTEALQNILMPITQRAYEQAQQAGGAEGFDPNAFQGGDAGQQKADDGVVDAEFTEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RIMM_THEVB
Sequence: MVTPFPEVSEWLCIGQIVGAHGLRGEVKVKPFSDFPERFTVPGCRWLRSPRQPQPYAVTLLRGRFLPRAEQFVVTFAEISDRTAAEALKGAEILVPASDRPPLAANEYHLMDLIGLAVYHQGERVGEVVGLVNAGNDLLEVQLLDPAPKAPQSVYIPFVPAIVPVVDLAARRIEIDPPLGLLP
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_SYNJA
Sequence: MTQLAVPSPAAPTLPDLVEIQRESFLWFLREGFEEELLSFSPIVDYTGKLELHFLPEYRPGDPSKGYKINKPRYDPEEAKRRDATYQAQIRVPTRLINKETGEIKDMDVFIGELPLMTDRGTFIINGAERVIVNQIVRSPGVYYKSELDKNGRRTYSASLIPNRGAWLKFETDKNGLVWVRIDKTRKLSAAVLLKALGLSDSEIYDSLRHPEFFQKTMEKEGHYSEEEALMELYRKLRPGEPPTVSGGQQLLESRFFDPKRYDLGRVGRYKLNKKLNLNVAENVRVLTVTDILAVIDYLINLEYDIGHVDDIDHLGNRRVRSVGELLQNQVRVGLNRLERIIRERMTVSESENLTPASLVNPKPLVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRERAGFAVRDIHPSHYGRICPIETPEGPNAGLIGSLATHARVNQYGFIESPYYRVENGVVRKDLGMVYLTADEEDEYRVAPGDVPVDAEGRITADLVPVRYRQEFTTAHPSEVHYVQVSPVQLISVATSLIPFLEHDDANRALMGANMQRQAVPLLKPDRPYVGTGLEAQAARDSGMVVVSRTSGVVTYVSADEIVVRPDDGGDPIVYRLQKYQRSNQDTCLNQRPLVYAGDRVVPGQVLADGPATEGGELALGQNVLVAYMPWEGYNYEDAILISERLVYDDVFTSVHIEKYEIEARQTKLGPEEITREIPNVGEDALRNLDENGIVRIGAWVEAGDILVGKVTPKGESDQPPEERLLRAIFGEKARDVRDNSLRVPNGERGRVVDVRIFTREQGDELPPGANMVVRVYIALKRKIQVGDKIAGRHGNKGIISRILPIEDMPYLADGTPVDVVLNPLGVPSRMNVGQVYECLLGWAAEHLGVRFKLMPFDEMHGLEASRLTVEAKLREAREKTGKDWIFNPEGKYCGKIQVFDGRTGEPFDQPVTVGRAYMLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRFGEMEVWALEAFGAAYILQELLTVKSDDMVGRNEALNAIVKGKPIPRPGTPESFKVLVRELQSLCLDVSVHKVEVDSDGQTRDVEVDLMADVSSRHTPSRPTYESVTSEDLSPAAGGTFTLARRSREEDEDREEEDDF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: LEUD_ENDTX
Sequence: MSDIILKGKVHKYGSNVNTDEIIPARYLNTTDPTILSKYCMEDIDKNFVKNVKAGDIIVAENNFGCGSSREHAPIAIKASGISAVIANSFARIFFRNSINIGLPILESQKAVKAIENGDAVEINLTKGIIKNITKNESYQSQPFPEFMQKVIKSGGLLGYIKS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: HSP83_DROSI
Sequence: MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.  Required for piRNA biogenesis by facilitating loading of piRNAs into PIWI proteins (By similarity).
What are the official names of this protein?
Heat shock protein 83, HSP 82.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR45_MOUSE
Sequence: MACNSTPMGTYEHLLLNVSNTLDPGDTPLSAPLRISLAIMMLLMIVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAITLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRAKMIIAASWVLSFCISAPSFTGWTFMEVPARAPQCVLGYTEFPAERAYVVTLVVAVFFAPFGVMLCSYLCILNTVRKNAVRVHNQSDSLDLRQLTGAGLRRLRRQQQQASLDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSAFSRRFYYSASFYTTSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPHTFQILPKVPERIQRKIQPSTIYVCNENQSAV
What is the function of this protein?
Orphan receptor.  May play a role in brain function.
What are the official names of this protein?
Probable G-protein coupled receptor 45, PSP24-1, PSP24-alpha.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TI110_ARATH
Sequence: MNPSLVTAINAPISPSPRSPLLSHFLPTLPHRFSKSECLSRRRYRVSFPRSSAASSDQLSVSTQAKNPGIHGNKKELTGLQPIVEKMTPPVRLATSAVVLAASLATGYGLGLRLAGSRNIAFGGAAVAGAAGGAVVYALNSAVPEVAAISLHNYVAEFEDPASVTKDDVEKIADRYGVNKGDEAFQAEICDIYCRYVTSVLPTEGQSLKGDEVAKIVKFKNALGIDEPDAAAMHMEIGRRIFRQRLETGEREGDAEQRRAFMRLVYVSALVFGDASSFLLPWKRVLKVTDAQVEIAIRENAKQLYAERLKLVGRDINVENLVDLRKSQLSFKLSDELAEDLFREHTRKVVVENISSALSILKSRTRAAKSLASVVEELEKVLEFNNLLVSLKSHSEADQFARGVGPISLIGDESDFERRMDDLKLLYRAYVTDALSGGRLEENKLVAMSQLRNILGLGKREAEAISVDVTSKSYRKRLANAVSSGDLEAQDSKAKYLQKLCEELHFDAQKAGAIHEEIYRQKLQQCVTDGELSDDNVAALLRLRVMLCIPQQTVDTAHAEICGTIFEKVVRDAISSGVDGYDAETRKSVRKAAHGLRLSRETAMSIASKAVRRVFTNYIRRARAAENRTDSAKELKKMIAFNTLVVTEMVADIKGESSDKAPEEDPVQEKEEDDEDEEWGSLESLRKTRPDKELAEKMGKPGQTEITLKDDLPDRDRIDLYKTYLLYCVTGEVTRIPFGAQITTKRDDSEYLLLNQLGGILGLSSKEIVNIHVGLAEQAFRQQAEVILADGQLTKARVEQLDELQKQVGLPQPQAEKVIKNITTTKMANAIETAVNQGRLNIKQIRELKEANVSLDSMIAVSLREKLFKKTVSDIFSSGTGEFDETEVYQTIPSDLSIDVEKAKRVVHDLAQSRLSNSLVQAVALLRQRNSKGVVLSLNDLLACDKAVPAEPMSWEVSEELSDLYAIYSKSDPKPAPEKVLRLQYLLGIDDSTATALREMEDGALSSAAEEGNFVF
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  Forms a voltage-dependent cation-selective channel at the inner envelope of chloroplasts, which specifically responds to a transit peptide.  Associates with both the precursor and mature forms of the preprotein.
What are the official names of this protein?
Protein TIC110, chloroplastic, Translocon at the inner envelope membrane of chloroplasts 110, AtTIC110.
What is the protein family that this protein belongs to?
Belongs to the chloroplast envelope anion channel-forming Tic110 (TC 1.A.18) family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: ATPD_RUEST
Sequence: MSEPASISAGIADRYATAIFEIAAESNALDNLETSINDLAASLADSEDLRTLITSPLVSREEQAAAISAVADKMGLVDVLRNSLALMAAKRRLFVVPALIDALRARIAEARGEVTAEVVSAKALTKTQSEKLAKTLAERVGKKVTINATVDASIIGGLVVKVGSKMIDSSIRSKLNSLQNAMKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.