PharMolix/UniProtQA huggingface dataset:
Protein: LIPB_PROM2
Sequence: MVNRTAIIKQPDNISFFNDVYKLQKEYQESLILDNSNPDFIWIGEHQLCYTLGRGSNYDNLLFSLNDDNYDVFKIDRGGEVTCHMPGQLVTYLVLDLKNFNKDLNWYLRKIEEIIIKILGTFNIDCHSRDGFTGVWIGNKKIASIGIGCKRWITINGFSINIDCELENFNKIVPCGIENCLMANMIDYNKNLNIQEVKRIVKKIIQEEFNFDFVSK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYF_SPIOL
Sequence: MQTINTFSWIKEQITRSISISLILYIITRSSIANAYPIFAQQGYENPREATGRIVCANCHLANKPVDIEVPQAVLPDTVFEAVVRIPYDMQLKQVLANGKKGGLNVGAVLILPEGFELAPPDRISPEMKEKMGNLSFQSYRPNKQNILVIGPVPGQKYSEITFPILAPDPATKKDVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNSTATGIVKKIVRKEKGGYEINIADASDGREVVDIIPRGPELLVSEGESIKLDQPLTSNPNVGGFGQGDAEVVLQDPLRIQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RSMA_MYCTA
Sequence: MCCTSGCALTIRLLGRTEIRRLAKELDFRPRKSLGQNFVHDANTVRRVVAASGVSRSDLVLEVGPGLGSLTLALLDRGATVTAVEIDPLLASRLQQTVAEHSHSEVHRLTVVNRDVLALRREDLAAAPTAVVANLPYNVAVPALLHLLVEFPSIRVVTVMVQAEVAERLAAEPGSKEYGVPSVKLRFFGRVRRCGMVSPTVFWPIPRVYSGLVRIDRYETSPWPTDDAFRRRVFELVDIAFAQRRKTSRNAFVQWAGSGSESANRLLAASIDPARRGETLSIDDFVRLLRRSGGSDEATSTGRDARAPDISGHASAS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1287_AQUAE
Sequence: MKKKTGGMRIFKVFGLFLFSLIFFGLLSLATFPKFLLFDRLLIQNKIFLIAQKVKENSMSIELFKGKVYFQNREALEFDYTKLSLGFLSVNGKILCRGKISEISYSFLGSIETKFRDFSCTPFVKKVNGRIELSDGIYGRVKLEGFKTELALLDEINLNFKGQTFTGSVKYLGMELKGQGRITLNRKNFLMSKVDGEFKGNGVRIKVQGTLNNLRVYMK
What are the official names of this protein?
Uncharacterized protein aq_1287.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ADEC_DEIGD
Sequence: MTTASAASERAVRQRLVRVARGLEAGDLLVRGAQVVQPATGEVFGADVLVAEGRVAALVGPGLGVRAARTVEARGAYLAPGFLDAHIHIESSLLTPARFAAAVLPRGTTAVVAEPHETVNVMGLSGLRWMLEAGKGSGLRVFGSVPSSVPASPFECGGAVLDAAEVAEALRLPGVLGLAEMMNYPGVLNLERGAWEVLDAGYGGRIDGHAAGVAGRDLQAYAAAGPHSDHEATTPEEARERLRAGLWLMVREGSAARNLEALLPVLRERPRRAMLVSDDVSVDELLSLGHLDRLLRACVAGGLHPADAVALVTCNPAEYWGLHDLGLVAPGYHADFVLLRDLERFEVLDTFVGGVEAQAGSETPPLPGGGVNLGPSWATATFEVPASWPVMQVRPDQITTGVGAPGSGDARLVVADRYGRGEHAACWTSGTGLTGGALAISLLHDAHHVAVLGGSNADVRAAGRALEAMGGGVVVVAGGEVRSNLPLPYAGLMSDLPPQEAAARLSEVTAAARVLGCTLPYPVTTLSFLGLSVIPALKLTPRGLLDVGAWQLLPRETVRVGAEG
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: RNH_RHOBA
Sequence: MTDSKTEAAFKPVELYTDGACSGNPGPGGWAFVLRCPRTLKEIQRSGGQPHTTNNQMELMAVIRGLEALKEPCAVDLYSDSKYVGQGMSSWMAGWKSRGWKRKDGSKLVPVKNVELWQELDQQMQAHRVTYHHVKGHAGHTENELCDKLAVAAYQQYL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL331_LACGA
Sequence: MAVKKAALACTVCGSRNYSIAASKNRTQRLELKKFCKHCGKQTLHKETR
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RECA_TERTT
Sequence: MDANKEKALQAALQQIDRQFGKGTVMRMGDKELEAIPAVSTGSLGLDVALGIGGLPKGRIVEIYGPESSGKTTLTLQVIAEAQRKGGTCAFVDAEHALDPIYAAKLGVNVDDLIVSQPDTGEQALEVADMLVRSGAIDVLVVDSVAALTPKAEIEGEMGDHHVGLQARLMSQALRKITGNIKNANCLAIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGSVKDGDEVIGSETRVKVVKNKVAPPFKQTEFQILYGTGINRLGEVIDYGVKLGLIDKAGAWYSYNGDKIGQGKNNAIQYLREHSDVAQTLEDRLKAELLGQSFDEAVEAEAESE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRC19_YEAS1
Sequence: MRKPSITITTAKAIITPDYTLIKSHSKYQLPSRFQKLDADSPERSTVVKLFYRRFMRLKPFISNVKMVKDTYRDYVRYKFMKENYELKRYLVFNPDGLRSKIKLELLSNTKCCERILPVTEMQRTLEFVLKSCSYLPETKAQKWDIARDNTYCRQILKNLLTMQYEKYRSILHRGIGHDELDVKFSHLKTTSSPLTKLNKTEKKKIPLFKVFSDFDTTLIYLNETLGTRL
What is the function of this protein?
Involved in sporulation and maintenance of the mitochondrial DNA.  Is probably involved in a pathway contributing to genomic integrity (By similarity).
What are the official names of this protein?
Increased recombination centers protein 19.
What is the protein family that this protein belongs to?
Belongs to the IRC19 family.
Protein: MUG5_SCHPO
Sequence: MCYLSRMSSQQMQLTISGFENRIKILEDLMNEFDSNLYIRLKRECDFKLPKEYDVSIHALTILMKRHLSNMEPIDCYQDLDTGTLQTMLIFCCTLRMIEHYEKSLSNINFFSLSNDLKRLEEYNTSCSVLLSLYQRQLKKISTTIESYYLADTLRHNQNILNLCERIYNIQKLLNKREKASVLRH
What is the function of this protein?
Required for correct meiotic chromosome segregation.
What are the official names of this protein?
Meiotically up-regulated gene 5 protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_ECOL6
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PEX1_MOUSE
Sequence: MWSSDRLAGAGSGGAVVTVAFTNARDCFLHLPRRLVAQLHLLQNQAIEVASDHQPTYLSWVEGRHFNDQSENVAEINRQVGQKLGLSSGDQVFLRPCSHVVSCQQVEVEPLSADDWEILELHAISLEQHLLDQIRIVFPKAVVPIWVDQQTYIFIQIVTLMPAAPYGRLETNTKLLIQPKTRQAKESTFPKEGDAHGQVHSYGREQKGLSKELQTRQLHTNSEGITASNGRDPKVPGGPLKPSWWAVLGSMLSFGPDSKQESAWGSLELGAFKNMQSQAAPLEGTFRVCQVQPPSARTTTATSVFHKHCTAHVFPWDQEYFDVEPSFTVTYGKLVKLHSPKQQQDKSKQGVLLPDKEKQLSKSPDHKQISSNRSEEAAEACVLKVVWNGLEELKNATEFTESLELLHRGKVWIPDDLRKRLNIEMHAVVRITPLETTPKIPRSLKLQPRENLPKDVNEETIKTVFSSWVQQSATTMLPLVISKEERIKLEIKDGLREFSLSTVHSQEKEKEEGKTVFVLSSILLQKISVQVLLEPMIKEEQSAEIDFLLPSLTLSSLGGVSALGASAMEHITHSLLGRPLSRQLMALVAGLRNGALLITGGKGSGKSTFAKAICKEAQDTLDARVETVDCKALRGKRLESIQKALEVAFSEAAWRQPSVILLDDLDLIAGLPSVPEQEHSPEAVQSQRLAHALNDMIKEFVSTGSLVALIATSQLQQSLHPSLVSAQGIHTFQCVQHLQPPNPEQRCEILHSVVKNKLGCDISNFPDLDLQCIAKDTEAFVARDFTVLVDRAIHSSLSRQHSSSREDLTLTTSDFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILTVLSKSLALADDVDLQHVASVTDSFTGADLKALLYNAQLEALQGRLLPSGLPDGGSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLEQSLLSLEMSEILPDESKFNMYRLYFGSSYESELGNGTPSDLSSHCLSAPSSVTQDLPAAPGKDPLFTQHPVFRTPSQEGCQDLTQEQRDQLRAEISIIKGRYRSQSGEDESLNQPGPIKTTFAISQAHLMTALAHTRPSISEDEGKEFAELYENFQNPKKRKNQSGTVFRTGQKVTLA
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling.  Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel.  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
What are the official names of this protein?
Peroxisomal ATPase PEX1, Peroxin-1, Peroxisome biogenesis factor 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane. Note=Associated with peroxisomal membranes.
Protein: PLGA_HUMAN
Sequence: MEHKEVVLLLLLFLKSGQGEPLDDYVNAQGASLFSVTKKQLGAGSREECAAKCEEDKEFTCRAFQYHSKEQQCVIMAENKKSSIIIRMRDVVLFEK
What is the function of this protein?
May bind non-covalently to lysine binding sites present in the kringle structures of plasminogen.  This may interfere with the binding of fibrin or alpha-2-antiplasmin to plasminogen and may result in the localization of activity at sites necessary for extracellular matrix destruction (By similarity).
What are the official names of this protein?
Plasminogen-like protein A, Plasminogen-like protein A1, Plasminogen-related protein A.
What are the subcellular locations of this protein?
Secreted.
Protein: CYNS_BURMS
Sequence: MTQSQHSQSPREALAERIVEAKTRKNLTFEQINEGTGLSVAFTTAALLGQHPLPADAARVVAAKLDLDDDAQRLLQTIPVRGSIPGGVPTDPTIYRFYEIVQVYGSTLKALIHEQFGDGIVSAINFKLDIKKVDDPEGGSRAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: MURB_PSEU2
Sequence: MSLQVQSAISLKPFNTFGVDVQARLFAEAHSDDDVREALAYSARHDVPLLVIGGGSNLLLSADVQSLVVRMASRGIRIVHEDCLESIVEAEAGEPWHPFVQSCLELGLAGLENLSLIPGTVGAAPMQNIGAYGVEIKDVFHSLTALDRETGELREFSLQDCAFGYRDSVFKHQVARWLILRVRFKLSRVARLHLEYGPVRQRLDEQGIDRPTPFDVSRAICAIRSEKLPDPAVLGNAGSFFKNPIIAAELYATIKQQHPGVVGYPQDDGQVKLAAGWLIEQAGWKGYRDGDAGVHKLQSLVLVNYGQASGLQLLSLARRIQTDIAERFGVELEMEPNLY
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFB_ECO81
Sequence: MKITLSKRIGLLAFLLPCALALSTTVHAETNKLVIESGDSAQSRQRAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVIIP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: Y996_MACCJ
Sequence: MLDENKMKRINELAQKKKATGLTDQEGKEQTLLRKEYLQSFRQSFKKTIENTTVIDPEGNDVTPDKVKEIQKLNNIRK
What are the official names of this protein?
UPF0291 protein MCCL_0996.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_BRUC2
Sequence: MATFSQKPAEVVKKWVLIDAEDLVVGRLASLVANRLRGKHKATFTPHVDDGDNVIIINADKVVLTGKKYTDKKYYWHTGHPGGIKERTARQILEGRFPERVLEKAIERMIPRGPLGRRQMKNLRVYAGPNHQHEAQQPEVLDVAALNRKNKGNA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: KDPC_MYCBO
Sequence: MRRQLLPALTMLLVFTVITGIVYPLAVTGVGQLFFGDQANGALLERDGQVIGSAHIGQQFTAAKYFHPRPSSAGDGYDAAASSGSNLGPTNEKLLAAVAERVTAYRKENNLPADTLVPVDAVTGSGSGLDPAISVVNAKLQAPRVAQARNISIRQVERLIEDHTDARGLGFLGERAVNVLRLNLALDRL
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ARCA_STRPF
Sequence: MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRA53_MOUSE
Sequence: MSCCGCCGGCGSSCCKPVCCCVPVCSCSSCGGCKGGCSSCGGCGSCGGCKGGCGSCGGCGSCGGCKGGCGSCGGCGSCGGCKGGCGSCGGCGSCGGCKGGCGSCGGCGSCGGCKGGCSSCGGCGSCGAASPSCVSPAAASPAVQALLLPVQLLQALLLPAQLLLVQLLLSLLLLHDCGSSCCPMSCSLPIYCQREI
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 5-3.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 5 family.
Protein: BOA14_BOTFB
Sequence: MEVSARVRVLMQHALHTIERRYKQVLLLIQQLSQHGIQSYSISPFHIHCIYSCYSL
What is the function of this protein?
Part of the gene cluster B that mediates the biosynthesis of botcinic acid and its botcinin derivatives, acetate-derived polyketides that contribute to virulence when combined with the sesquiterpene botrydial (PubMed:21722295).  Botcinic acid and its derivatives have been shown to induce chlorosis and necrosis during host plant infection, but also have antifungal activities (PubMed:21722295).  Two polyketide synthases, BOA6 and BOA9, are involved in the biosynthesis of botcinins.  BOA6 mediates the formation of the per-methylated tetraketide core by condensation of four units of malonyl-CoA with one unit of acetyl-CoA, which would be methylated in activated methylene groups to yield a bicyclic acid intermediate that could then either be converted to botrylactone derivatives or lose the starter acetate unit through a retro-Claisen type C-C bond cleavage to yield botcinin derivatives (PubMed:23203902).  The second polyketide synthase, BOA9, is probably required for the biosynthesis of the tetraketide side chain of botcinins (Probable).  The methyltransferase (MT) domain within BOA6 is probably responsible for the incorporation of four methyl groups (Probable).  The trans-enoyl reductase BOA5 might take over the enoyl reductase function of BOA6 that misses an ER domain (Probable).  The monooxygenases BOA2, BOA3 and BOA4 might be involved in further hydroxylations at C4, C5 and C8, whereas BOA7, close to BOA9, could potentially be involved in the hydroxylation at C4 in the side chain of botcinins (Probable).
What are the official names of this protein?
Botcinic acid biosynthesis cluster B protein 14.
Protein: MTO1_HUMAN
Sequence: MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVDGSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTPPRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLHLNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEKMITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL
What is the function of this protein?
Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.
What are the official names of this protein?
Protein MTO1 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
Protein: ALR_FRATO
Sequence: MNILKISKQTLRNNIKIIREYIGNAKMCFPVKANAYGHGIEDIVENTHDLVDFFAVANSLEAFRVTAVAKNPVLVFGVIYYEYIEKMISENIRVSIQDYEYIEKLEQIAKELDKKVYAHININTGMNRMGVDYNDACRTIQRAYESDWLILEGVYSHLACADNRDHPTNIKQKNRFDSIVKFTKGLSQDIICHLSNSYGFLGQKGICYDMVRPGILSYGFLPEFYVDRVIREIKPIARLLSKVVKIITLQEGEGVGYSLIYRGFEGEQLAVIPIGYGDGFPRELGDRGFVNINDVMYPMAGRMSMDGLTVSLGINEYDVKVGDTVELISAIPRNRNSAFSIAKQINTIEYDIMSTLNDRIIRKII
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: UVRB_CHLPN
Sequence: MTFQLHAPFAPCGDQPEAIARLSAGVRNQVKSQVLLGTTGSGKTFTIANVVANVNLPTLVLAHNKTLAAQLYQEFREFFPNNAVEYFISYYDYYQPEAYIARSDTYIEKSLLINDEIDKLRLSATRSILERRDTLIVSSVSCIYGIGSPENYTSMALVLEVGKEYPRNILTAQLVKMHYQASPIPQRSAFRERGSVIDIFPAYESELALRLEFLNDTLTSIEYSDPLTMIPKESVPSATLYPGSHYVIPEAIREQAIRTIQEELEERMAFFDDRPIEKDRIFHRTTHDIEMIKEIGFCKGIENYSRHFTGAPPGAPPTCLLDYFPEDFLLIIDESHQTLPQIRAMYRGDQSRKQSLVEYGFRLPSAFDNRPLTYEEAQKYFRKVIYVSATPGDTEVQESSGHIVQQIIRPTGIPDPMPEIRPATGQVDDLLEEIRLRLSQKHEKILVISITKKLAEDMAGFLSELEIPAAYLHSGIETAERTQILTDLRSGVIDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRSTSSLIQFCGRAARNINGKVIFYADQKTRSIEETLRETERRRQIQLDYNKEHNIVPKPIIKAIFANPILQTSKDSESPKESQRPLSKEDLEEQIKKYEALMQRAAKEFRFNEAAKYRDAMQACKEQLLYLF
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNOT6_RAT
Sequence: MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSSSLWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKGNPLTQDILNLCLEPDGTRRLLNYLLDNLSGTAKRISTEQPPPRSWIMLQEPDRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIISLQEVETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKELIEMSSGKPHLGTEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRSLKSSVLGECGTIPLVLCADLNSLPDSGVVEYLSTGGVETNHKDFKELRYNESLTNFSCNGKNGMTNGRITHGFKLKSAYENGLMPYTNYTFDFKGIIDYIFYSKPQLNTLAILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFLPQVNGIHLPGRR
What is the function of this protein?
Poly(A) nuclease with 3'-5' RNase activity.  Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm.  In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors.  Mediates cell proliferation and cell survival and prevents cellular senescence.
What are the official names of this protein?
CCR4-NOT transcription complex subunit 6, CCR4 carbon catabolite repression 4-like, Carbon catabolite repressor protein 4 homolog, Cytoplasmic deadenylase.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: ENO_CHLT2
Sequence: MFDVVISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQGKGVLQAISNVEKVLVPALQGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALAKAAANTLQRPLYRYLGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLKEAVRMGAEVFNALKKILQNRQLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPREDISLALDCAASSFYNTQDKTYDGKSYADQVGILAELCEHYPIDSIEDGLAEEDFEGWKLLSETLGDRVQLVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAIRLATIQGYATILSHRSGETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIEEEMGPEALFQDSNPFSKA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.