PharMolix/UniProtQA huggingface dataset:
Protein: NDE1A_XENLA
Sequence: MDDLENNIFNSVEEEILYWKSVAMKYKQCSEEAQQELQEFQEASREYEAELEAQLLQTEGRNRDLFSENNRLRMELDAIKEKYEEQHSENYVQISTLEGDLSQTKAVRDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLENELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPKSNMVSPETERMDTSVQASIAIPSAPLTPLSQRGCASTLTSPLSFRTSLDDGYSGTPLTPCARISALNIVGDLLRKVGALESKLASCRNFVHEQSPNRPLTSVSARMKKTREGIENRLSIASGSSVEKGLIKRLEFGSFPSNTPMQGMHSPQGVVKMII
What is the function of this protein?
Required for centrosome duplication and formation and function of the mitotic spindle.
What are the official names of this protein?
Nuclear distribution protein nudE homolog 1-A, Mitotic phosphoprotein 43, MP43.
What is the protein family that this protein belongs to?
Belongs to the nudE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the interphase centrosome and to the mitotic spindle.
Protein: LEP_TETNG
Sequence: MDYTLALALSLLQLSMCTPVPMMQDSGRMKTKAKWMVQQLLVRLKDNVWPHFDMPPTFSADDLEGSASIVARLENFNSLISDNLGDVLQIKAEISSLTGYLNNWRHNNCKEQRPRTAVPGLPQEPQRRKDFIQSVTIDALMSMKEFLNLLLQNLDHLEIC
What is the function of this protein?
May function as part of a signaling pathway that acts to regulate the size of the body fat depot.
What are the official names of this protein?
Leptin.
What is the protein family that this protein belongs to?
Belongs to the leptin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MQO2_STAAC
Sequence: MAKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPAIESSNERNNAGTGHAALCELNYTVLQPDGSIDIEKAKVINEEFEISKQFWGHLVKSGSIENPREFINPLPHISYVRGKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLMMKGREDNPGIMAASKIDEGTDVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNGQWEVTVKNRLTGEKFKQVTDYVFIGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACTNPQVIEQHDAKVYGKEPPGTPPMTVPHLDTRYIDGQRTLLFGPFANVGPKFLKNGSNLDLFKSVKTYNITTLLAAAVKNLPLIKYSFDQVIMTKEGCMNHLRTFYPEARNEDWQLYTAGKRVQVIKDTPEHGKGFIQFGTEVVNSQDHTVIALLGESPGASTSVSVALEVLERNFPEYKTEWAPKIKKMIPSYGESLIEDEKLMRKIRKQTSKDLELGYYEN
What are the official names of this protein?
Probable malate:quinone oxidoreductase 2, MQO 2, Malate dehydrogenase [quinone] 2.
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: TIAS_SULIL
Sequence: MKYLIGIDDHDSYKFGCTTHFSVILTSYLYKNHNTILLDLPYLVRLNPNIPWKTRGNASIKLIVDFNGTKKELADIIFSYSVKYVKNVSLALEHGRRPGIAIIEYDKYKSLFEKLYDFYIKGILDIIPIDYAKKFAEKNDIEIRGDRGIIGSIAALGMSGDYTYELITYRKKENWLKKRMINEDSVKRVDEETFPLTFANYDYINDSPLITPHGNDPILYGIRGTSIEHLIKAMELIESNEDINFFAVFKTNQNTDIHFQKVGNRFYQEIKKVIQIKNIKILEGGDVMIRTTDDDILFVYKETGELNSAAKLLKEGDEIVAYGAIKPSITYGKIIELERFEILKLNDLQLINPKCPICGGPTKSLGKNKGYKCKKCKYIINTANKSMKNIIRNLSLGIYQTRAYRHLTRPIFLTLENNNQSFHEERKFLDMYRSELYKLDYHL
What is the function of this protein?
ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
What are the official names of this protein?
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS, tRNA(Ile2)-agm2C synthetase, tRNA(Ile2) agmatidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the TiaS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STXB6_BOVIN
Sequence: MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSVTNKKPTQASITKVKQFEGSTSFVRRSQWMLEQLRQVKGIDPNRDSAEFDLLFENAFDQWVASTASEKCTFFQILHHTCQRYLTDRKPEFINCQSKIMGGNSILHSAADSVTSAVQKASQALNERGERLGRAEEKTEDLKNSAQQFAETAHKLAMKHKC
What is the function of this protein?
Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis.
What are the official names of this protein?
Syntaxin-binding protein 6.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: COAX_MALP2
Sequence: MKNNQEYILVVDIGNSYTKIGIFEKEKENTTSIILFPTDSETNIATLSKKMNVFKKYNIKHSIVGSVVPKLKPTYFKTIKKMFNIEPYYISETTKYSFLIDESPNKELGDDLKALCEYCVSVNKNCIGISFGTAIASVYLKNNSLVGASIAAGLGFGLNKLIEKASLLKKSKIDKFSSDFFGTNTISALESGINNLRSGFAYNFYNQAKKDNLNSDLKCIITGGESYNINISSFEYEINKEAILLGFKKIYFLNN
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAA_SALTI
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVAGFENPEGSLTGGIQSTGNYPGKARNATELRADLEQALRLIPGPKRLNLHAIYLESDTPVARDQIKPEHFKNWVEWAKANRLGLDFNPTCFSHPLSADGFTLSHPDAKIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLEALDEVISEKFDPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPRLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHNLFDRVHIGLDFFDASINRVAAWVIGTRNMKKALLRALLEPTDQLRQLEASGDYTARLAMLEEQKSLPWQAVWEMYCQRHDTPAGSQWLDSVRTYEKEILSKRS
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_NOCFA
Sequence: MTDTTLRHRTARVERVTKESSIVVELDLDGTGRTDISTGVPFYDHMLTALGAHASFDLSVRAEGDIQIEAHHTVEDTAIVFGQALGKALGDKAGIRRFGDAFIPMDETLAHAAVDVSGRPYCVHTGEPEHLLHAVIPGSPVRGTGEPGAPYSTVLNRHVFESIALNARIALHVRVLYGRDQHHVTEAEFKAVARALRAAVEFDPRVSGVPSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4M_CAEEL
Sequence: MLEFLFISLLWLFKPIYFLLFTVMFSFLIFNNFSWGGLFLVLDSYSFILLIVMSLFILGIIVISEKNNNLLILSEILVFICIIFFIPSNMMMLYMFFELSMFPILVMILGYGSQIEKINSSYYLMFYAAFCSFPFLFVYFKSNFLLVFTYYNFVISWEMFFILSLSFMMKFPIYFLHLWLPKAHVEAPTTASMLLAGLLLKLGTAGFLRILGSLSFVHNNVWILIAFLGMILGSFCCVFQSDSKALAAYSSVTHMSFLLLSLVFITMSSKISSVMLMLAHGYTSTLMFYLIGEFYHTSGSRMIYFMSSFFSSSMIMGILFSVVFLSNSGVPPSLSFLSEFLVISNSMLISKSMFVMIFIYFVVSFYYSLFLITSSLMGKGYHNFNTWNVGFSAPLVLMMYNVFWLSVFY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: HPRK_AZOSB
Sequence: MRQTSVARLYEDQGPRLQLTHVSGPLDAVLSVAEERMWPADLVGHLNLIHPTRLQVLGAAELEWARRQSREKVAHHLNGILSARPPAIIVADGCETPNIVHGVCTAHNVALFSTPHPSASVIDQLRLYLSRQLAEKISLHGVFMDVLGIGVFITGNSGAGKSELALELISRGHGLVADDIVEFSRTAPTVLEGRCPELLKDFIEVRGLGILNIRTIFGETACRRKMRLRLVCHLERRQPGQDDPNRLPVQQEQQVILGVSTPRVTLPVAAGRNLAVLLEAAVRSTILQLRGVDSTQEFIDRQSRMLMGDGDGL
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: NUON_PERMH
Sequence: MSILQQLVSGIGVPNFGVILPEIIILITAFILLVVELLIRSRVVISAITVTGLILAAASVFLIKKGDVTFYGLYVVDMFSLIFKLFLILTTLFVVINLKPYLDSKKSYYGEYYYIILFALIGMMIMVSSPNLVTFYIGLELSAVSIYILAGTFRKDYRSKEGAFKYLIMGGMGTAIISYAIALIYGRTGSFDFYTIASLINSNNIDVGISGALILLIIGLALKAAAVPFHFWTPDAYEGAPTPITAFMAVAAKIATFAVILRVMVEAFPFISKEWSFAWAILAAASMIIGNIIALRQENVKRMLAYSSVAHTGYILAAIAAPTGMGFSALIFYSLIYIFMGIGGFILLSALEKNHNWSNHIDDFKGLAKRSPMMALFMLIFMFSMLGIPPTVGFMGKLGVFLALIGSDIWWLAVTLVVMSIVSAGYYLRVVIYMYMYEPVSKARLNFAMTEMFTVAFMAVFVLILGIYPTVFWGISTTLSSLLIAGIGR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FA9_PANTR
Sequence: MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVDTGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
What is the function of this protein?
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
What are the official names of this protein?
Coagulation factor IX, Christmas factor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KIF22_XENTR
Sequence: MAKRVSILDQHKKPSSARVRVAVRLRPYMEKEDEKAPAACVRGLDSQSLEIVNWRNQLETMQYQFDAFYGDSATQREIYMGSVCHILPHLLIGQNASVFAYGPTGAGKTHTMLGNPSQPGVIPRAVRDLLQMTRTAAGGPENENWTYTITMSYVEIYQEKVMDLLEPKNKDLPIREDKDHNILIPGVTQKTINSFGDFDEHFIPASQNRTVASTKLNDRSSRSHAVLLIKVQKSQQVSPFRQLTGKLYLIDLAGSEDNRRTGNQGIRLKESGAINSSLFTLSKVVDALNQGLPRIPYRDSKLTRLLQDSLGGTAHSVMIANIAPEQKYYFDTLTALNFAAKSKQIINKPFSQETTQSIAALPAMKRPREEAETAAGSRQRKKSKTDSTESSPNTSMDAASKRKLNLAALDPAVVERLLKLDKILTEKGMKEAQLLSTPKRERMALLKKWEESQMEIERLKEKQKELEQKAIEAEARLEKSTNSDCNLSDSSVSECTFRAPLRGRNTSTAKAKKVLRVLPMQGNSQLQSTIEEGIPVFEKKKKKPVSCDGRENQPTWEVNVRTDLLESGRERILKLLNTGSVKELKSLQKIGDKKAKLIIGWREVNGPFKNVEDLASLEGISAKQVTSFIKANILSIIAS
What is the function of this protein?
Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis.  Binds to microtubules and to DNA.
What are the official names of this protein?
Kinesin-like protein KIF22, Chromokinesin kid.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton.
Protein: LEUC_KLEP7
Sequence: MAKTLYEKLFDAHVVYEAQNETPLLYIDRHLVHEVTSPQAFDGLRAHGRQVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVRGRLHAPKGKDFDDAVAYWKTLKTDDGATFDTVVTLQAAEIAPQVTWGTNPGQVISVTDNIPDPASFSDPVERASAEKALAYMGLKSGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNLK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: NRBP_DROPS
Sequence: MSNSQANAGSSGSADEPTLNPSGSATLVPNLTTTNASSQATPASTIPQQQQPQQSQPQPQPQPPPHIVGASTADAGGGVGVVVAGGSEGVNLDSSPRESGDDSEDESEILEESPCGRWLKRREEVDQRDVPGIDCVHLAMDTEEGVEVVWNEVQYANMQELKSQEEKMRQVFDNLLQLDHQNIVKFHRYWTDTQQAERPRVIFITEYMSSGSLKQFLKRTKRNAKRLPLESWRRWCTQILSALSYLHSCTPPIIHGNLTCDSIFIQHNGLVKIGSVVPDAVHYSVRRQWDRESAREQERERGAHYFQAPEYGAAEQLTAALDIYAFGMCALEMAALEIQPSNSESTAINEETIQRTICSLESDLQRDLIEKCLNPQPQGRPSANDLLFHPLLFEVHSLKLLTAHCLVFSPANRTMFSETAFDGLMQRYYQPDVIMAQLMSGGQERQYRLADVAGADKLEKFVEDVKYGVYPLITYNGKKPPNFRSRAASPERADSVKSATPEPVDTESRRIVNMMCSVKIKEDSNDIIMTILLRMDDKMNRQLTCQVNENDTAADLTSELVRLGFVHLDDQDKIEVLLEETLKAGVMSDGAGAESSGAGVTTTATMAALEQLERNWSISDADKTMGSSMSSPATAMMYVPQDQQQYQQQQQEADVDQSGTTSN
What is the function of this protein?
May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus.
What are the official names of this protein?
Nuclear receptor-binding protein homolog, MLF1-adaptor molecule.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex.
Protein: CYB_DASHA
Sequence: MINMRKTHPLMKIINHSFIDLPTPSNISAWWNFGSLLGMCLIIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNHGWLLRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLAEWIWGGFAVDKATLTRFFAFHFILPFIIMALAVVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDALGFMLLLLVLLLLALFSPDLLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLAVLASILILLIIPLLHTANQRSMMFRPVSQTLFWILTANLITLTWIGGHPVEQPFIIIGQLAPMPYFLLILVMMPLAGLFENYMLKPEW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DBP5_CRYNJ
Sequence: MSDAQAPPASTSWADMVDEDEKQKQEQNMSNQNDGWGETATETSAPAPPPASAPVSSSNNDGWGEPAPSAPADNGWADAGASNGGSGANNNDGWFDAPVPPSSQPPKKEASDIQLQDDTEGLITNTFQVEVKLADLQGDPNSPLYSVQSFKELNLHEDLMKGIIAAGFQKPSKIQEKALPLLLSNPPRNLIGQSQSGTGKTAAFTLNMLSRVDPTIPTPQAICIAPSRELARQIQEVIDQIGQFTQVGTFLAIPGSWSRNSRIDKQILIGTPGTLVDMLMRGSRILDPRMIRVLVLDEADELIAQQGLGEQTFRIKQLLPPNVQNVLFSATFNDDVQEFADRFAPEANKIFLRKEDITVDAIRQLYLECDSEDQKYEALSALYDCLVIGQSIVFCKRKVTADHIAERLISEGHAVASLHGDKLSQERDAILDGFRNGETKVLITTNVIARGIDIPAVNMVVNYDVPDLGPGGNGPDIETYIHRIGRTGRFGRKGCSVIFTHDYRSKSDVERIMNTLGKPMKKIDARSTTDIEQLEKALKLAMKGPA
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: IFRD1_MOUSE
Sequence: MPKNKKRNAPHRGGGGGGGSGAATSAATAGGPHRTVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGLKNALSSKVLYEFVLERRMTLTDSIERCLKKGKSDEQRAAAAVASVLCIQLGPGFESEEILKTLGPILKKIICDGAASIQARQTCATCFGVCCFIATDDITELYSTLECFENIFTKSYLKEKDTNVTCSTPNTVLHISSLLAWTLLLTICPINEVKKKLELHFHKLPSLLSCDDVNMRIAAGESLALLFELARGMESDFFYEDMDSLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETVKFGPERMYIDSWVKKHTYDTFKEVLGSGMQYHLQTNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKCRDKRADVGEFL
What is the function of this protein?
Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF.  May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal.
What are the official names of this protein?
Interferon-related developmental regulator 1, Nerve growth factor-inducible protein PC4, TPA-induced sequence 7, TIS7 protein.
What is the protein family that this protein belongs to?
Belongs to the IFRD family.
Protein: RL28_HAEDU
Sequence: MSRVCQVTSKRPAVGNNRSHALNATRRRFLPNLHTHRFWVESENRFVTLRLTAKGMRIIDKKGIDAVLAEIRARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PSRP_SHESH
Sequence: MLRKVFYISDGTAITAEVFGHAVLSQFPVEFDALTIPFVETEAKAHDVKLQINDCFITTGERPLVFHSIVKAEIRDIIYSSEGLDYDFLNTFVAPLELQLGMKASPVVHRTHGKANEGYEARIDAINYTMDNDDGQTLKNIDKADLVLLGVSRCGKTPSSLYLSMQFGIKAANYPFVEDDMDNLKLPTALKENKSKLFGLTIDPVRLHEIRKSRMDNSRYSSLRQCRIEVKEVEMMYKRERIPFVNTTNHSVEEIATKILDVTGLERHMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: ERD2_CAEBR
Sequence: MNIFRITADLAHAVAIVILLLKIWKSRSCEGISGRSQILFAVTFFTRYLDLFTSFYSLYNTVMKVLFLAGSIGTVYLMWVKFKATYDRNNDTFRIEFLVIPSIILALIINHEFMFMEVMWTFSIYLEAVAIMPQLFMLSRTGNAETITAHYLFALGSYRFLYIFNWVYRYYTESFFDPIAVVAGIVQTVLYADFFYLYITRVIQSNRQFEMSA
What is the function of this protein?
Required for the retention of luminal endoplasmic reticulum proteins.  Determines the specificity of the luminal ER protein retention system.  Also required for normal vesicular traffic through the Golgi (By similarity).
What are the official names of this protein?
ER lumen protein-retaining receptor.
What is the protein family that this protein belongs to?
Belongs to the ERD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: OTUD5_XENTR
Sequence: MTILPKKKPPPPSDPEGNGERSGSGGADSHSRSGARPRSSPPPRWAYPGNPAPPERHPAGTPRPQQASPPPCSGGSGGAGSGPLGEGALGPCCCCTGAGGCCSGPGHSKRRRQGVSAGPGAPGSSPDREDGAGNNSEDEYETAARTQAIDPDTAEQQEHWFEKALQEKKGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQYGTEPINTFHGIQQNEDEPIRVSYHRNIHYNSVVNPNKATIGVGLGLPSFKPGFAEQSLMKSAIRTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQARQPRKASATCSSATAAASSGLEEWSGRSPRQRSTAGSPEHPDLHAELCMKPPSPAATLMLGKPPSPCAPGPSNQTCAGADRATSPLVSLYPALECRAIMQHMSPTAFGLKDWDDDEILASVLAVSQQEYLDTIKKSTLRRDSSPDHS
What is the function of this protein?
Deubiquitinating enzyme that may function as negative regulator of the innate immune system.  Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro) (By similarity).
What are the official names of this protein?
OTU domain-containing protein 5, Deubiquitinating enzyme A, DUBA.
What is the protein family that this protein belongs to?
Belongs to the peptidase C85 family.
Protein: KDSA_VESOH
Sequence: MKLLDFEVGINHPFFLIAGPCVIESEALALETATYLKRVTEDLGINFIYKSSYDKANRTSTNSFRGLGVKEGLRILQKVKDEVGVPVLTDVHEDTPLSEVASVVDMMQTPAFLVRQTNFIQNVCKQGIPVNIKKGQFQAPWDIGNVVNKAYETGNRLITICERGTSFGYNTLISDMRGLSTMRSTGCPIVFDATHSVQQPGGNGLTSGGQREMVPVVARAAIGVGVSGFFMETHPNPNEAFSDGPNMVPIDKIDELLKTLQELDAVTKKHGFLEDSL
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDNB_SHEON
Sequence: MSFKNFKVVEKMIFGRGSFVQLDDVLAAQRKADDDFVVFLVDDVHQGKPLEARIPVKAQDLLIWVNVDEEPSTIQIDALTEQVQAFNGKLPVSVVGLGGGSTMDVAKAVSLMLTNPGGSAMYQGWDLIKKPAVHHIGIPTISGTGAEASRTAVLCGPVRKLGLNSDYTVFDQIIMDSELIDGVETDQWFYTGMDCYIHCVESLEGTFLNEFSKAYAEKAMDLCRQVYLEDHPEKDDKLMMASFMGGMSIAYSQVGACHAVSYGLSYILGYHHGIGNCIAFDVLEEFYPEGVAEFRLMMKKHNITLPKNICKDLPDETIAKMVAVTKSMGPLWANVYGPTWEEKVTDEMLTALFRRI
What is the function of this protein?
Catalyzes the first step of the biosynthesis of Kdo8N (8-amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno-octulosonate).
What are the official names of this protein?
3-deoxy-alpha-D-manno-octulosonate 8-oxidase.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: TRUA_STACT
Sequence: MRILVKISYQGSNFLGFQIQQHGRTVQQQFEKILKRMHKRHVRIHPSSRTDRGVHAIEQYFHFDTELNIAPDKWQYAMNSALPDDIYVNEVSIVDDDFHCRYDCVGKRYRYKVYQGKHRDVFMSGLKTFYADSLDLEKMNEAAQQFIGTHDFTGFCSQKTEVESKERTLYQSEIIKTENGFDYIVTGSGFLYNMVRVLVAFLIEVGKGKRQPEEVPILLEAKDRKQVPFTAPAEGLYLEKIYLAPQELINDFGPDIKIHRKKSLEND
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL18_ALKEH
Sequence: MDKKATRLRRARRARAKIAELKVHRLSVHRTPRHMYAQIIAPDGGRTLVAASTVEKDLRSRAEGTGNCSAAAEVGRLIAERAKAAGVERVAFDRSGFKYHGRVKTLADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: LEU3_PROMP
Sequence: MKRYKVVLLSGDGIGPEISEISITILKKLSKKYGFNLDIKEEYFGGIAYEKHNDPAPKETLDQCKASDAVLLACVGDVKYDTLPRELRPESGLLKLREALNLFANIRPVKIRKSLLDSSSFKKEVIENVDLIVVRELIGGIYFGQPRGEITQTKIKKAFNTMVYDSNEIERITEVAIKIANQRSKKICSVDKSNVLEVSQLWRDTVSLVASKENDLALSNMYVDNAAMQLVKDPGQFDVILTSNLFGDILSDLAAMITGSIGMLPSASLSNSGPGVFEPVHGSAPDIAGKNIANPIAMALSTSMMLKIGLNEIEAADDIEIAIDNVLSKGYRTSDLDNGNCQVLSCSEIGEKIIQEI
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOD_BUCAP
Sequence: MPTLHIKSEKNAFSNIVLMPGDPVRAKYIAENYLANPVQINDTRLMLAYTGYYKNKKISVMSHGMGIPSASLYVRELILEYNVKKIIRVGTCGTIQNNIKLRDIVISMGASTDSKINRIRFNNHDYAAIADFEMIFHAFSTAKKMNFKVHIGNFFTTDSFYTESEDMLKILKKYNIIGIDMETAGIYAVAAELKAQALSICTVSDHIIKKDAVSSKDRESSFHNMITLSLETTLLL
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.