PharMolix/UniProtQA huggingface dataset:
Protein: NUR1_YEAST
Sequence: MGSNDLINEAYDDSEVVGEERESKSAWMKRWYQLLTSPLDLQLVINEKLEMINWDAYAKSLAKPLGNFLTILFFIIRLLQDNLIKPNYYKLNVKSGAFDLSKSNKLKEFDYLWEISSSFQNNNQFYAFQSWYFVTLRFLNNLFRFTIFILLSLNLYVSCKFMFGYFKTYNLFHLKKEFNSPNLTKHNLKDLSKEYYEDIYKQSLWSMLKHFFRGSRDDGPHVNQNEDEIFFQLRKWIPTNFMINLFVSFSPTAIVFLSFSDVSFTSAIAIVFHQYILDYIITKRFQRSVDDDLILSSAALQEYEDKHIMARINQCSNIDTLSSAMGTRSKTPRIFTTHSLCGEEIREVYNYEKREFEALPKMTESVPGSRETRIKDYGGISQVSDHQSHPIGFHYSPRMSPYYRDKVLDNNLAQSSSNENLEKGGAYLPNQDQNRPSKSLSPLRKTPLSARQKRFEGSEFNVLNKNDINSILRSPKKKKNYHKR
What is the function of this protein?
Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability.  Required for rDNA repeat stability.
What are the official names of this protein?
Nuclear rim protein 1.
What is the protein family that this protein belongs to?
Belongs to the NUR1 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein.
Protein: SYT_STRPQ
Sequence: MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQLIDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGFYYDTDNTEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELINEHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLERYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNCPHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQIQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALDEMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKTLRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEEKSVNVRRYGSKATHTESVEEFVENILADIARKSRPDAQA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_ECOLU
Sequence: MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2B5_DABRR
Sequence: SLLEFGMMILEETGKLAVPFYSSYGCYCGWGGKGTPKDATDRCCFVHDCCYGNLPDCTPKPDRYKYKRVNGAIVCEQGTSCENRICECDKAAAICFTKNLNTYSKIYMLYPDFLCKGELKC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that has a low enzymatic activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 VRV-PL-V, svPLA2, P2-1, P2-2, P3, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ALDOA_RAT
Sequence: MPHPYPALTPEQKKELADIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSSLAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYIKRALANSLACQGKYTPSGQSGAAASESLFISNHAY
What is the function of this protein?
Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis (By similarity).  In addition, may also function as scaffolding protein (By similarity).
What are the official names of this protein?
Fructose-bisphosphate aldolase A, Muscle-type aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+).
Protein: MQO_METFK
Sequence: MTSSLDTDILLVGGGIMSATLGTLLHQLNPELRITLVELQAEVATESSDGWNNAGTGHAGYCELNYTPQDADGSVPIARALKINAAFEESLQFWAWLVEKGILREPASFINPTPHSSFVWGEKNVAFLRKRHQALRAHHLFADMEYSQDPAVLQQWMPLVMAGRDPSIPVAATRVAYGSDVDFGSLTRQLVQHLQGRPGFKLLTRHAVTGLKQQGSWQVKAVDLSQGKPVEIRAGFVFLGAGGATLPLLQKSAIQEARGYGGFPVSGQWLVCHNPDVIHQHHAKVYGKAPLGAPPMSVPHLDTRIINGKPALLFGPFAGFTTRFLKRGSLLDLVNSVKRSNLKSMLGAGRHHMDLTRYLIGEVFQSHQQRMAALRNFYPLANESEWSLVSAGQRVQIIKQCEHQGGKLEFGTEIVSSADGSLAALLGASPGASTSVPAMLEVLQRCFSPQLQSAAWQERMREMLPSYGQSLIEDAELLRAVRYHTLSRLKLT
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: NSP2_ROTH7
Sequence: MAELACFCYPHLENDSYKFIPFNSLAIKCMLTAKVDKKDQDKFYNSIIYGIAPPPQFKKRYNTNDNSRGMNYETPMFNKVAVLICEALNSIKVTQSDVASVLSRVVSVRHLENLVLRRENHQDVLFHSKELLLKSVLIAIGHSKEIETTATAEGGEIVFQNAAFTMWRLTYLEHKLMPILDQNFIEYKITVNEDKPVSESHVKELIAELRWQYNKFAVITHGKGHYRVVKYSSVANHADRVYATFKSNNKNGNMLEFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKRLLFQKMKRESNPFKGLSTDRKMDEVSQVGI
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: CTAA_RICFE
Sequence: MQKSLITKWLFISCIMVIAMIVIGGITRLTGSGLSIVEWRPVTGILPPFSFESWQAEFAKYKAFPEYNSINYGMTLSQFKFIYLLEFVHRLLGRITALIYIVPLIYFYFKDVIKNRDILPYIIALLLFCVQGFMGWYMVKSGLLNSPSVSHFRLAFHLIIAVIIYHILFYQLIKNRCDILLIPSQTDLKLPLIFSGIAITVIYVQIFLGAMVAGLDAGLIYNSFPLMGDNFIPMEIKDNFFNLANLHDPVFIQFIHRLGGYSVFLVVVVLVICLLKIEHPKLNKIAYFLMIALLMQISTGIITLLYSVPIIIASIHQLFAIILLSIIIWCYFIIKTS
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPD_CLOB8
Sequence: MQEYLEKRYALALYEIAEKNNKVDEYLRDLTDICDIFDENKEFYEVINHPKINTAKKKQLFTDLFKGKIDEELLSFMMILIEKDRILQLREILDQMEKIDLERRNTIRGIVKTVVPLLDEELEQLKAIFEKKYEKNILFDTKIDKSLLGGVYVKVGNDIIDGTIKSKVEEMKELMLKKE
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HBB1_CHAMP
Sequence: MVHLTGEEKAAVTGLWGKVNVEEVGGEALGRLLVVYPWTQRFFDSFGDLSNAGAVMGNAKVKAHGKKVLNSFGEGLKNLDNLKGTFAKLSELHCDKLHVDPENFRLLGNVLVVVLARHFGKDFTPPVQAAFQKLAQGVATALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-1, Beta-1-globin, Hemoglobin beta-1 chain, Hemoglobin beta-I chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YYCD_BACSU
Sequence: MIKKYAITPNVDADGWFIEVENVAPTALYTSKDAAIEKAKQVAKENSPSKLVIYDQFKNVEEEHSF
What are the official names of this protein?
Uncharacterized protein YycD.
Protein: RS27_PYRAE
Sequence: MPVRFSKVLIPQPKSKFIKTRCPDCGNEQITFSHAAMVVRCLVCGRVLAIPTGGKAKLAGHVVKVLE
What are the official names of this protein?
30S ribosomal protein S27e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: SPF27_PONAB
Sequence: MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPPSGQKKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF
What is the function of this protein?
Required for pre-mRNA splicing as component of the activated spliceosome.  Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.  May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.  The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
What are the official names of this protein?
Pre-mRNA-splicing factor SPF27, Breast carcinoma-amplified sequence 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SPF27 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: SSB_BRUAB
Sequence: MAGSVNKVILVGNLGADPEIRRLNSGDMVANLRIATSESWRDRQTGERKDRTEWHSVVIFNENLAKVAEQYLKKGAKVYIEGALQTRKWQDQNGNDRYSKEIVLQKFRGELQMLDSRSEGGEGRSFGGGGNRNQMSDYSGGGGDFGSSGPSSGSSGGFSRDLDDEIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: LAGE3_MOUSE
Sequence: MQTAHTGLSHTADGADGQTSRCCPGNAGTKAVIPSGAHPVARALEASRNSSKSMVPLTQRPGTRHHRFSLFVPFPTSLEAEIACGSLVPDVEPHRGLVGKELKVSGCMLEVRWIAEDSRLLRLSIINFLDQLSLVVNTIQLFGPPVSC
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  LAGE3 functions as a dimerization module for the complex.
What are the official names of this protein?
EKC/KEOPS complex subunit Lage3, ITBA2 protein homolog, L antigen family member 3.
What is the protein family that this protein belongs to?
Belongs to the CTAG/PCC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYP_BARHE
Sequence: MRLSQYFLPLLKENPKEAEIISHRLMLRAGMIRQQTSGIYSWLPLGKKVLDKICKIIREEQERAGAIEILMPTIQSADLWRESDRYDDYGLEMLRIKDRQKRDLLYGPTNEEMVTDIFRSYIRSYKDLPLNLYHIQWKFRDEIRPRFGVMRSREFLMKDAYSFDLDYEGSKISYNRMFVAYLRTFSCLGLKAIPMRADTGPIGGKLSHEFIILAETGESAIFCDKHFLELTVPDSSIDFSDKAILANIVKQWTSFYAATEEMHDEEEWAKISDNNRLSARGIEVGHIFHFGTKYSAPMGAKVMGQDGKEHLVSMGSYGIGPSRLVAAVIEASHDENGIIWPKSIAPFDFGIINMKPDDEKCTHACETLYKGLRYAGFDPLLDDRNERPGSKFATMDLIGLPTQIIVGPKSVAQNEVEIKDRKTGIKKSLTVENVLNQFSVI
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPRG_MYCBO
Sequence: MRTPRRHCRRIAVLAAVSIAATVVAGCSSGSKPSGGPLPDAKPLVEEATAQTKALKSAHMVLTVNGKIPGLSLKTLSGDLTTNPTAATGNVKLTLGGSDIDADFVVFDGILYATLTPNQWSDFGPAADIYDPAQVLNPDTGLANVLANFADAKAEGRDTINGQNTIRISGKVSAQAVNQIAPPFNATQPVPATVWIQETGDHQLAQAQLDRGSGNSVQMTLSKWGEKVQVTKPPVS
What is the function of this protein?
Constitutes a host TLR2 agonist (toll-like receptor).
What are the official names of this protein?
Lipoarabinomannan carrier protein LprG, 27 kDa lipoprotein, Antigen P27, Lipoprotein LprG, Triacylglyceride transfer protein LprG.
What is the protein family that this protein belongs to?
Belongs to the LppX/LprAFG lipoprotein family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid- anchor. Secreted, cell wall. Secreted.
Protein: RECA_ECOLC
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_THIDA
Sequence: MRVIFAGTPPFAAAALEALVAAGHEIVLVLTQPDRPAGRGMKLAASAVKQAALAHGLPVYQPTTLKTPEAQARLADCAADVMVVAAYGLILPQAVLDLPRLGCLNIHASLLPRWRGAAPIQRAILAGDCETGITIMQMAAGLDTGAMLAKTVVPIADADTAATLHDALAVAGAAAIVSALSAYDTLVPQTQDEREASYAAKLSKEEARLDWQQPAEALARAVRAFNPVPGAWTLLAGAPFKILRAEAAPQGEADAPPGTVLRADPAGIVVACGGGALVLHEIQAAGSKRMTAAAFLAGRALSAGTRLGA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: FBK48_ARATH
Sequence: MSSSNEPPRKTDQPSSSSASASASPSLFLSLPLEIISMILARVPKRYYPILCSVSKNMRSLVRSPEIHKARSLLGKDYLYIGFIDENYRPVYDYWYTLRRIENSTTENLFESIEFPYPSEPNRFSMNAVGPKIFFISESCTPSSRLSIFDTRFGELRQGPCLLVKRGYNCVGLVGGKVYVIGGYQDDEIAAESFDLNTQTWEAAPIPDEKESHRWICKANVSFDRKVCALRSREGMTCYDTRDGSCQRSEMPNDQWSRVGLCVIDNVLFVYFSRFGLMWYDSKLMLWRVVYGFDLDNARSVGIGEYYGKLAFIWEKPSLNVSESKEIWCRMIGLLRSEVGIHGAAEPSQLVEIVPNGYRMCHCLSLSG
What are the official names of this protein?
F-box/kelch-repeat protein At2g44700.
Protein: WDY_CULQU
Sequence: MERKSTLSSPGSSLESVDHSQPQLLHRYLTRENVQHLHQLFDQRKQLLPDELRAELFVLTGVRFSDEEFETLFMKINTDRDNFCQWDELISYLILGFHNDDPLAVQESLDLPISLDMSVKLGRQTYPVIKIEYSPMVSYDGTVNWSQGFWATSTQEAVINFWKRDWKHEKTGKAFSVDLKRAKTWILDTAVLPDLNYFCVACLEHELRIYDIIGSGFTLKIIVNRIPNPINALKYHFSASTRSKLIMGDYKGVLRVVEFYPERKEPFKFDAASTVTRLSFRDLLNGSYPQMECVDYGRLLPDIVRQLQFVEPTYSFLACSENDPLAPSGSRKKLYTSVIIQHLTKLDKITKIKVPKGVTCFAYDHVKDFLVTGGPDGELRMWDIRRPENPVASLSGHNAGVVFMFLQDGSQKIYSMDTKKIVKIWDVLNRILIQTYSQFSTTLYKTVPACAYYNDLNRELVIGANKVLSAPCCPKIPLEVTDGESHTQPISVLLYNPLFKVLISCGLDSYIIVWDHTMNRKLTIITDAHTQVVNGLLEQVQITAACFDPKLQLLLTGARDGTLKVWNFNSGSCMSSMSIQEGCEVTAVFWEPTSILAMGWNHAVVEFPVGTTGMDFPRGIDWQKLHSDDILCASVTHSEPKAIATCSYTGEIVFWLMETGQPYQRFNAAKPQQKIPVNAMTTKIGKPKRRSRMSVFMPQEQLRQRRLTRIVMPVKAEQLRQLTIHELLFLESRPMHPEVGTLLSSLDTGVIQVYSHHVDGGFLGSFNAVHMAGDRVVSMTTDPYNKFLFTGSYLGYVKTWLLEASFNRAALKMQFPFLLDDIIPGRAKRSVANQPLPWLLNSYQAHRNCITALSYIPATKLLLSASSDHTIRIWSLAGRYIGLLGSPVKWATIDADVPIPKEYGFRIPPDLQREVSFTTAQVLRGGERAIKLKSRILQEASERRRTEAVETYGQPLEDPIIKPEVFPYGYRAGFVHDAKMDYSFRETPIFEHLSIQNLTKLKVVDSKRVVEKVEGLDFSNDGDRIDTYHERNI
What are the official names of this protein?
WD repeat-containing protein on Y chromosome, WD40 Y.
Protein: MURE_STAA3
Sequence: MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQGCKLVVVNKEQSLPANVTQVVVPDTLRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATMIHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSSHGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNNDDSFSEYLRTVTPYEVFSYGIDEEAQFMAKNIQESLQGVSFDFVTPFGTYPVKSPYVGKFNISNIMAAMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNKLIDAVQPFVKQKLIFLVGMAGERDLTKTPEMGRVACRADYVIFTPDNPANDDPKMLTAELAKGATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRDDLIGLEAAYKKFGGGPVD
What is the function of this protein?
Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_STAAW
Sequence: MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDHFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERDSQKGIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: TRM5_SCHPO
Sequence: MHLQIRTVHNMAELLHPNKVEMKPFLKNLDKNLFKKTYNLVAAKVSPKKVGLLNKVCKKDLLDWPRVKHVYQQNNEKLVLLNRDASLDGTRGLSDATVSFIKENNIELVPFQLTLDYDYWRADDILDAILPPGEKEDHPSGFTAVGHIAHMNLREEWLPYKYIIGKVILDKNPSIETVVNKTDTIDTKFRTFQMEVLAGKDDFIVTQSESNCKFRFDFSKVYWNSRLSTEHDRLIQQFQPGDAVCDVMAGVGPFACPAGKKNVIVFANDLNPYSYESLVENIFLNKVANFVKAFNQDGREFIRSSVQKLLGFSKDEKAITVFPPRKRARKLEENKDPVRQDIPIPPVFSHYVMNLPGSAIEFLDAFKGCYYGLEYLFKDRSLPKVHVHCFCRFPDPEEDLINRIYASLGYRFSPEEVDFYYVRKVAPNKDMYCCTFTLPGSIIFAKPVSG
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: RS11_NAUPA
Sequence: MAKRKVTKKKKIKKQVGRGVVYISATFNNTMITVTDEMGNALCWSSAGALGFKGSKKSTPFAAQQAVEDVMAKAKEYGIKEVGIKVQGPGGGRETAVKTVGAIEGIKVLWMKDVTPLPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PEX14_MOUSE
Sequence: MASSEQAEQPNQPSSPPGSENVVPREPLIATAVKFLQNSRVRQSPLATRRAFLKKKGLTDEEIDLAFQQSGTAADEPSPLGPATPVVPVQPPHLTPQPYSPRGSRWRDYGALAIIMAGIAFGFHQLYKRYLLPLILGGREDRKQLERMAASLSELSGTVAQTVTQVQTTLASVQELLRQQQQKVQELAHELATAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPSWQIPVKSSSPSSPAAVNHHSSSDISPVSNESTSSSPGKDSHSPEGSTATYHLLGPQEEGEGVLDVKGQVRMEVQGEEEKREDKEDEDDEDDDVSHVDEEDVLGVQREDRRGGDGQINEQVEKLRRPEGASNETERD
What is the function of this protein?
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (By similarity).  The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity).  Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.  Plays a key role for peroxisome movement through a direct interaction with tubulin (By similarity).
What are the official names of this protein?
Peroxisomal membrane protein PEX14, PTS1 receptor-docking protein, Peroxin-14, Peroxisomal membrane anchor protein PEX14.
What is the protein family that this protein belongs to?
Belongs to the peroxin-14 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.