PharMolix/UniProtQA huggingface dataset:
Protein: INT13_XENLA
Sequence: MKTFSESHKTVFVVDHCPYMSESCRQHVEFDMLTKNRTQGIIPLAPISKSLWTCAVEASMEYCRIMYDIFPFRKLVNFIVSDSRSRTLNSWNREDQNLQELMAALAVIGPPNPRADPECCSILHGLVEAVESLCKITDFQHESRTALMGNADWVANRGRIICITNAKSDSHVQMLEDCVNETIHEHNKMAAGSDHLMQIQKCHLVLLHTYPVGEDSLVSDRPKKELSNVLVSEVHSVKAGRHLSTKLNQLVQLHFDLASTTITNIPMKPTLSVCDQEEQHANTSANYDVELLHHKEAHVDFIKSGEGYTGSSSIRENSLKETVTLKWCTPRTNSVELHYCTGAFRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLMPFPEQSYQMDGGPEVPLERAKEQLERHTRYWPMIISQTTIFNMQAVVPLASVIVKESLSEEDLLNCQKTIYNLVDMERKNDPLPISTAGTRGKGPKRDEQYRIMWNELETLVRAHVSGSERHQRVMECLMACRSKPPEEEERKKRGRKREDKEEKGEKLNKDHEHDKKGQESERIKSVLDQEKEDLAEAEVIKDSPDSPEPPNKKPHIVIEDTGPAEKSKGPMSLLSLWSSRINTANSRKHQEFVGRLNSVNNKAELYQHLKEENGGEGVENGKASRQ
What is the function of this protein?
Crucial regulator of the mitotic cell cycle and development.  At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling (By similarity).  At G2/M phase, may be required for proper spindle formation and execution of cytokinesis (By similarity).  Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (By similarity).  Plays a role in gastrulation and early embryogenesis (PubMed:15737938).
What are the official names of this protein?
Integrator complex subunit 13, Cell cycle regulator Mat89Bb homolog, Germ cell tumor 1, Protein asunder homolog, Sarcoma antigen NY-SAR-95.
What is the protein family that this protein belongs to?
Belongs to the asunder family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M.
Protein: FV1_MOUSE
Sequence: MNFPRALAGFSSWLFKPELAEDSPDNDSPDNDTVNPWRELLQKINVADLPDSSFSSGKELNDSVYHTFEHFCKIRDYDAVGELLLAFLDKVTKERDQFRDEISQLRMHINDLKASKCVLGETLLSYRHRIEVGEKQTEALIVRLADVQSQVMCQPARKVSADKVRALIGKEWDPVTWDGDVWEDIDSEGSEEAELPTVLASPSLSEESGYALSKERTQQDKADAPQIQSSTSLVTSEPVTRPKSLSDLTSQKHRHTNHELNSLAHSNRQKAKEHARKWILRVWDNGGRLTILDQIEFLSLGPLSLDSEFNVIARTVEDNGVKSLFDWLAEAWVQRWPTTRELQSPDTLEWYSIEDGIERLRELGMIEWLCVKATCPQWRGPEDVPITRAMRITFVRETRETWKSFVFSLLCIKDITVGSVAAQLHDLIELSLKPTAAGLTSVGSVGVLSLSPWKHQSNS
What is the function of this protein?
Retroviral restriction factor that prevents infection by gammaretroviruses.  Acts by interacting with the capsid protein ca after entry of the virus into the cell.  This interaction presumably disrupt the capsid thereby inactivating the viral genome, making it unable to enter host nucleus and integrate into host genome.
What are the official names of this protein?
Friend virus susceptibility protein 1.
Protein: SYS_LACLS
Sequence: MLDIKKIRADFDGIAAKLATRGVEKEKLEKLHDLDIKRRELIVKSEALKAERNSVSDEISQVKRAKGDASTQIAAMQKVSAEIKAIDAELAEIEENLNEIIIMLPNLPHESTPIGADEDDNVEVRRVGQTPTFNFEPKAHWDLGEDLGILDWERGGKVTGSRFLFYKGAGARLERALYNFMLDEHGKEGYTEMITPYMVNQESMFGTGQYPKFKEDTFELKDDRGFVLIPTAEVPLTNYYRGEILDGSELPIKFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPDQSYDELEKMTANAENILQKLGLAYRVVALSTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNCEDFQARRAQIRYRDEDGKVQLLHTLNGSGLAVGRTVAAILENYQNEDGSITVPEILRPYMGGLEVIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HM10_CAEEL
Sequence: MAVDEMQLAASMQMSNQMSNSQRMSFAIHEILGIQGNAYLSHGYCPQGTFLSNQPNFMDIGSCGVSGFDRQLCGTDSIGNAPAPLMYRMPISTSEVITSEPQTHVSSSSILSSATTSNSSGGGSSGGGGKASKRKKRRHRTIFTQYQIDELEKAFQDSHYPDIYAREVLAGKTELQEDRIQVWFQNRRAKWRKTEKTWGKSTIMAEYGLYGAMVRHSLPLPETITKSAEAADPQQSAAPWLLGMHKKSMEAAAHLESVEKCDMSDSDDDDRPVTPPVQRQVKNEYKPRIIEHVQQQAPQHQSSLNFDTSLVVSSSLSQLHFQDSQMIPNNNASLKLYHDYNNPM
What is the function of this protein?
Transcription factor (PubMed:15177025).  Binds to a sequence motif, 5'-TTATTGGCTTCGTTAA-3', which may be involved in AIY interneuron function, in the regulatory elements of target genes; binding is more efficient, in vitro, together with LIM/homeobox protein ttx-3 (PubMed:15177025).  Required for larval development and for cell fate specification and migration of CAN neurons (PubMed:2361334, PubMed:9475729, PubMed:11493519).  Required for generation, or placement, and differentiation of the ALA neuron, and may play a role in ALA axon migration (PubMed:20501595).  Involved in development and function of the AIY interneurons, acting by regulating expression of LIM/homeobox protein ttx-3 (PubMed:11493519, PubMed:19386265, PubMed:15177025).  Also acts in an autoregulatory feedback loop to maintain its own expression (PubMed:19386265).  Modulates lifespan, perhaps acting in the AIY interneurons (PubMed:21055415).  Plays a role in fertility and egg-laying behavior (PubMed:21055415).
What are the official names of this protein?
Homeobox protein ceh-10.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EGF_FELCA
Sequence: MLLFLIILLPVVFKFSFVSLSVLQGWDCSEGSSSGKGNSTCVGPEPFLIFSHGGSIFRIDLDGTNYEQLVADAGVSVIMDFHYYKERLYWVDLERQLLQRVFLNGTRQETVCNIEKNVSGMAINWINEELIWSNQQEGIITVTDMKGNNSRVLLSALKYPANVAIDPVERFIFWSSEVAGSLHRADLNGVEVKILLETSERITAVSLDVLDKRLFWIQNNRDGSNSYICSCNYDGGSVHFNKHLTQHSLFAMSLFGDRIFYSTWKKKTIWIANKRKDMVRINLNPSFVPPGGTKVVHPLLQPKAESDAWAPGQKLCLRKGNCTGSVCEQDSKSHLCTCAEGYTLSPDGKHCEDVNECAFWNHGCTLGCENIPGSYYCTCPVGFILLPDGKRCHQLISCPSNTSKCSHDCVLTSDGPICFCPEGSVLETDGKTCSGCSSPDNGGCSQLCLPLSPVSWECGCFPGYDLQLDKKSCAASGPQPFLLFANSQDIRHVRFDGTDYGSLLSQQMGMVFALDHDPVENKIYFAHTALKWIERANMDGSQRERLIEEAVDVPEGLAIDWIDRKFYWTDRGKALIEGSDLNGKHREIIIKEEVSQPRGIAVHPMAKRLFWTDMGINPRIESSSLQGIGRRVIASSDLVWPSGITIDYLTDKLYWCDAKQSVIEMANLDGSKRQRLAQNDVGHPFAIAVFEDHVWFSDWTMPSVIRVNKRTGKNRVRLRGSMLKPSSLVVVHPLAKPGSDPCLHQNGGCEHICKERFGSAQCLCREGFVKAPDGKMCLALNGHQIPPAVGSEADLSNQVTPLDVLSRNRGSEDNSTESQHMLVAEIMVSDNDDCGPIRCGTWGQCVSEGENATCQCLKGFTGDGKLCSDINECGTSTTVCPPTSSKCINTEGGYVCQCSEGYRGDGIHCLDIDECQLGIHTCGENATCTNTEGNYTCMCAGTLSEPGQMCPDSTPPSVLMEDGRYSVRNSYQECPPSYDGYCLYNGVCMYIEAVDRYACNCVFGYVGERCQHRDLKWELRHAGQGRQRQVTVVAVCVVALVLLLLLGLWGAHCYRTKKLPSKNLKNPYEESSREVSRPTDSEAGMASCPQPWFVVIKEHQNLRNGSQSMALKDSEAADVSQFSSRETGSVQLPSRRNEPQVYMGAEQGCCIPPSSDKGPGPHGMQWGFHLPSCEAQPIALGVEKSQSLLSANPILQQRASDLPHQKKLTQ
What is the function of this protein?
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.  Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
What are the official names of this protein?
Pro-epidermal growth factor, EGF.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: COWN_RHOPT
Sequence: MSASFDRYVSFQHCDWEGRSERVMQRLQRHVEAAENPFWAYFAQKRAELRDKQGLDDLRILHNYLPTLRELLEDNGDLETLEMLEDLEANLM
What is the function of this protein?
Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO).  Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.
What are the official names of this protein?
N(2)-fixation sustaining protein CowN, CO weal-nitrogenase.
What is the protein family that this protein belongs to?
Belongs to the CowN family.
Protein: LSPA_BUCBP
Sequence: MKIPLIYNRILILFFFIANIIILDQVSKKWIINNLLLHEKKPLISIMNIFYVRNYGTAFNFFSNNPGEKNYILCLISSIAILIILKTMYNNTTIENFFYNIPSAFIISGAIGNFIDRCYLGYVIDFIDFHINNWHFATFNIADVSIFIGSVLFIYHNKYFLKN
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL35_ECOSM
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RNPA_STRPB
Sequence: MKKTYRVKCEKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGISVGKKIGNAVTRNAVKRKIRHVIMALGYQLKSEDFVVIARKGVESLEYQELQQNLHHVLKLAQLLEKGFESEEKH
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: URE1_ANADF
Sequence: MTRRMDRRQYAQVYGPTTGDRVRLGDTALVLEVDRDLTVYGDECVFGGGKVLRDGMGQAAGAPPEEVLDLVITNALVLDQGGVTKADVGIRGGRIAALGKAGNPDAMAGVTPGMTIGPGTECIAGEGLILTAGGVDSHIHFISPQQAYEAIASGVTTMLGGGTGPATGTNATTCTPGARHVALLLQATDALPVNIGLLGKGNAASPEGLAEQVRAGAVGLKLHEDWGTTPAAIDTCLRVADQLDVQVAIHTDTLNESGCAEHSIAAFAGRTIHTFHTEGAGGGHAPDIIRVCGEPNVLPSSTNPTRPFTVNTVDEHLDMLVVCHHLDPSLPEDLAFAESRIRRETIAAEDVLHDLGAISMMSSDSQAMGRVGEVVTRTWQTADKMRRQRGRLPEERGDNDNLRIRRYLAKYTINPAVAHGLSHEVGSVEPGKLADLVLWRPALFGAKPELVLKGGLIAWAQMGDANASIPTPQPVVARPMFGALGRAVGATSVAFVSRASLEGGAVQGYGLAKRLVAVHGCRGLGKKDMRLNDALPRMEVDPETYEVRADGVLLRCEPAARLPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTF_SHIFL
Sequence: MSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: NADK_DEHMC
Sequence: MYKKIGIIYHPLNPAACDLAIKLTAKLDSLGIENWSDSAWQADKLTSKMQNTQLIFTTGGDGTILRTAHAILPLEIPILSVNLGKVGFMTELSPEDAISGLEKVLAGDGWIDERSLLEAEYLPHDSAQSRQFFVMNDAVVARGQVARVICVSVDINSQPFTTYKADGAIVSTATGSTGYSYAAGGPVLQPNSADIILTPILPHLGRGYSLVLPSDSTVDLQVNTWHEATLSIDGFINMQVSSGDTLRLRRSSKKVKFMRLRPNNYFYKELDTKLKGNNESVYDR
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANGP2_HUMAN
Sequence: MWQIVFFTLSCDLVLAAAYNNFRKSMDSIGKKQYQVQHGSCSYTFLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKLENYIQDNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF
What is the function of this protein?
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling (PubMed:15284220, PubMed:19116766, PubMed:19223473, PubMed:9204896).  Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1 (PubMed:15284220, PubMed:19116766, PubMed:19223473, PubMed:9204896).  In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression.  In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (PubMed:15284220, PubMed:19116766, PubMed:19223473, PubMed:9204896).  Involved in the regulation of lymphangiogenesis (PubMed:32908006).
What are the official names of this protein?
Angiopoietin-2, ANG-2.
What are the subcellular locations of this protein?
Secreted.
Protein: B4GN4_HUMAN
Sequence: MPRLPVKKIRKQMKLLLLLLLLSCAAWLTYVHLGLVRQGRALRQRLGYGRDGEKLTSETDGRGVHAAPSTQRAEDSSESREEEQAPEGRDLDMLFPGGAGRLPLNFTHQTPPWREEYKGQVNLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVKKLAVSPKWKNYGLRIFGFIHPARDGDVQFSVASDDNSEFWLSLDESPAAAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASRRYYFELLHKQDDRGSDHVEVGWRAFLPGLKFEVISSAHISLYTDESALKMDHVAHVPQSPASHVGGRPPQEETSADMLRPDPRDTFFLTPRMESSSLENVLEPCAYAPTYVVKDFPIARYQGLQFVYLSFVYPNDYTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDKEEGDEDEEDEVQRRAFLFLNPDDFLDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPVTSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPALGRWREDAIDWQRTFSVGAVDFELLRSDWNDLRCNVSGNLQLPEAEAVDVTAQYMERLNARHGGRFALLRIVNVEKRRDSARGSRFLLELELQERGGGRLRLSEYVFLRLPGARVGDADGESPEPAPAASVRPDGRPELCRPLRLAWRQDVMVHFIVPVKNQARWVAQFLADMAALHARTGDSRFSVVLVDFESEDMDVERALRAARLPRYQYLRRTGNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEGRLAFAPVVMRLSCGSSPRDPHGYWEVNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRNFYHHYHSKRGMWSVRSRKGSRTGAS
What is the function of this protein?
Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.
What are the official names of this protein?
N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1, NGalNAc-T1, Beta-1,4-N-acetylgalactosaminyltransferase IV, Beta4GalNAc-T4, Beta4GalNAcT4.
What is the protein family that this protein belongs to?
Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: Y402_RICCN
Sequence: MKTYNIVIASDHSGYELKSEIINYLEQKSLKIYDCGTNNTQTVDYPDYAKKVVDIIIEKSAPIGILISDTGIGMSIAANRSSEIRAALCNNILTAENAKAHNDANILILGAKTIDQKIVFDIIDKFLTTQFEGGRHSTRLSKIK
What are the official names of this protein?
Putative sugar phosphate isomerase RC0402.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: TSP3_MOUSE
Sequence: MEKPELWGVLALLLLCSYTCGSQDLQVIDLLTVGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTALLRLRGPSRPSPGLQLYVDCKLGDQHAGLPALAPIPPAEVSGLEIRTGQKAYLRMQGFVESMKIILGGSMARVGALSECPFQGDDSIHNAVTSALQSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPSPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCDDINECAHADPCFPGSSCINTMPGFHCEACPPGYKGTRVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCVPARTCHSPAHSPCHIHAHCLFERNGAVSCQCNVGWAGNGNVCGPDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGVPDYIPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVILDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSISGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWRLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV
What is the function of this protein?
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions.  Can bind to fibrinogen, fibronectin, laminin and type V collagen.
What are the official names of this protein?
Thrombospondin-3.
What is the protein family that this protein belongs to?
Belongs to the thrombospondin family.
Protein: Y2224_YERPG
Sequence: MINKTLLGLSLGALMFTAGSAVAADYKIDKEGQHAFIEFRIKHLGYSWLYGSFNDFDGSFTFDDKNPAADKVNVVINTNSVDTNHAERDKHLRGKSFLNVAKFPQATFESTEVKKNGDGYSVIGNLTLNGVTKPVTLESKLTGQGNDPWGGYRAGFEANGNIKLKDFNITTDLGPASQEVELILSVEGVQVK
What are the official names of this protein?
UPF0312 protein YpAngola_A2224.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: ABRX1_CHICK
Sequence: MEGESTSALLSGFVFGALAFQHLSTDSDTEGFLLGDVKGEAKNSITDSQMDDVEVVYTIDIQKHIPCYQLFSFYNSAGELNEPALKKILSGRKKSVIGWYKFRRNTDQIMTFRERLLHKNLQSHLSNQGLVFLLLTSSVMTESCSTYRLEHALHRPQEGLFQKVPLVVTNLGMAEQQGYRTVSGSCASSGFVRAVKQHRSEFFYEDGSLQEVHKINEMYATLQEELKKMCSDVEVSERSVEKLLTEVSQLKEEINRKKQHKISSGGNKDQLEEPKENVLLCQALRTFFPSSDLQTCIVSFKGRISKNCCKIDHNINIMDKLTLMVEERDFTEAETKLVTKRKVRVTTTGPKSLKKLRSLQLDQELHQDEEDCNQETKLALSSAETDEEALENPKDTNEYSYSPTF
What is the function of this protein?
Involved in DNA damage response and double-strand break (DSB) repair.  Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1.  The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.  This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
What are the official names of this protein?
BRCA1-A complex subunit Abraxas 1, Coiled-coil domain-containing protein 98, Protein FAM175A.
What is the protein family that this protein belongs to?
Belongs to the FAM175 family. Abraxas subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Protein: SMG_XANC5
Sequence: MKESILDVLLYLFEHYFSEDADLVRDRDSLQNGLIQAGFSPAEISKAFDWLDALSEQRPSVARPHVDGPVRIYHGPELDKLDVDCRGFLLFLEQHRILDADQRELVLDRAMALDQDELDLDDLKWVVLMVLFNQPGAEAAYAWMETQMFLDEPESVH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: YJV5_YEAST
Sequence: MVSDDIPSSKRLRPCQFILFYLRVHVFHAKKRSEIPKLLRVQEQARSRNYSRDNSSRLAGRLNYTFQELSPAFSVRYVYKLLQQDALGCFLWNFSPSPHTSLLNPRGGDIIKLRESVNA
What are the official names of this protein?
Putative uncharacterized protein YJL215C.
Protein: FTHS_BACCR
Sequence: MTTTTTVKSDIEIAQEASMKKIQEIAADLNILEDELEPYGHYKGKLSLDIFKRLQDEKDGKVVLVTAINPTPAGEGKSTVTVGLGQAFNKIGKKTVIALREPSLGPTMGLKGGAAGGGFSQVVPMEDINLHFTGDIHAITTANNALAAFIDNHIQQGNTLGIDTRKIVWKRCVDLNDRALRNVVIGLGGPVQGVPREDGFDITVASEIMAVFCLATDIQDLKARLSRIVVAYNFANQPVTVKDLGVEGALTLLLKDALKPNLVQTLENTPAIIHGGPFANIAHGCNSVIATTMAAKLGDYVITEAGFGADLGAEKFLDIKARAAGIKPEAVVIVATIRALKMHGGVAKDQLKEENVDALAKGMENLQKHVETIQSFGVPFVIAINKFITDTDAEVTYLQEWCNERGYAVSLTEVWEKGGQGGVDLAEKVLKEIEKGENNYAPLYELELPLEEKIRTIAQKVYGAKDIEFAPKARKQLAQYEGEGWSNLPVCMAKTQYSLSDDVTKLGRPSDFIVTIRELKPSIGAGFIVALTGTMLTMPGLPKQPAALQMDVNEDGKAVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: ACD11_HUMAN
Sequence: MKPGATGESDLAEVLPQHKFDSKSLEAYLNQHLSGFGAEREATLTIAQYRAGKSNPTFYLQKGFQTYVLRKKPPGSLLPKAHQIDREFKVQKALFSIGFPVPKPILYCSDTSVIGTEFYVMEHVQGRIFRDLTIPGLSPAERSAIYVATVETLAQLHSLNIQSLQLEGYGIGAGYCKRQVSTWTKQYQAAAHQDIPAMQQLSEWLMKNLPDNDNEENLIHGDFRLDNIVFHPKECRVIAVLDWELSTIGHPLSDLAHFSLFYFWPRTVPMINQGSYSENSGIPSMEELISIYCRCRGINSILPNWNFFLALSYFKMAGIAQGVYSRYLLGNNSSEDSFLFANIVQPLAETGLQLSKRTFSTVLPQIDTTGQLFVQTRKGQEVLIKVKHFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDKLKEMAKVEGLWNLFLPAVSGLSHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDEDSYVINGKKWWSSGAGNPKCKIAIVLGRTQNTSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQVCGGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKRLTAKI
What is the function of this protein?
Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA (PubMed:21237683).  Probably participates in beta-oxydation and energy production but could also play a role in the metabolism of specific fatty acids to control fatty acids composition of cellular lipids in brain (Probable).
What are the official names of this protein?
Acyl-CoA dehydrogenase family member 11, ACAD-11.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: RHG1A_ARATH
Sequence: MQGERASLGYLSEALNFEHGSSSSNGVIDHWENIHSLGDNDLQDYMIANSESNTSLANSVYHEQQGLRRFSLGEASSSGTKDEASSHNEQRMETRCFDGRGNEIIDLDPVFAQPSGTNQPVQNVNLNAEYIEIHEDINPYRGRSGFIEANGPGTRVSQPGRSFEENGVGTGSSVEGRRASCKRKALEGSISQSSSGGYHDFQRGESSSWTPGSTVFRPGNGLNISGSLDNGPRGMVSGTVPNFPVSAPNFPVSAIAESSSRNICVRSNPSDHQETVNPSTFAAGTVVRRPVPPSQLNLSRHLPADQHSLDLRPGQSFVVSRNPNSTPVSIPPGSRTMLPPFRWTGSSLVGGTSNSTAPVERNLHLDETRSRSIPGNTLEIPMFAAPEVGNFARSQSSRNVTNGNLNSASSVSRTGSTTSVPPPPPPSSNLAWTSYQNSPHYQRRRTERSELARRSLLSSLAADATNQRSGDHPTLRSLAPPASSDGLVLQPGGDNSQMHNRAYSRAGPLFDRQGDSVVGIPHPLRALAAASRGRSRLMVSQMQNVLDVMRRDANNNNLRLEDVMLLNHSVLFDGATGHDRYRDMRLDVDNMSYEELLALEERIGDVCTGVNEETISNRLKQRKYKSNTKSPQDAEPCCVCQEEYTEGEDMGTLECGHEFHSQCIKEWLKQKNLCPICKTTGLNTAKKRRIA
What is the function of this protein?
Probable E3 ubiquitin-protein ligase that may possess E3 ubiquitin ligase activity in vitro.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase RHG1A, RING-H2 finger G1a, RING-H2 zinc finger protein RHG1a, RING-type E3 ubiquitin transferase RHG1A.
Protein: IOLG_MYCGI
Sequence: MTDLRIAVLGVGVMGADHVARITSRISGARVAVVNDHLVEKAEQLAASIPGCSAVADPLDAIADADVDAVVLATPGGTHEEQLLACLDQRKPVMCEKPLTTDVSTSLEIARREADLGRPLIQVGFMRRFDDEYVRLKALLDGGELGNPLMMHCVHRNPGVPAYFDSSLIVKDSLVHEVDITRYLFGEEIASVQIIKPTSNPGAPNGVVDPQIAILRTVSGRHVDVELFVTTGVAYEVRTEVVGEHGSAIIGLDVGLIRKKGPGSWGGTLTPGFRERFGPAYDTEIQRWVDAVHSGTNVCGPTAWDGYAAAAVCAAGVESLETGLPVDVQLADEVTSPSPQGVRESDGCR
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.