PharMolix/UniProtQA huggingface dataset:
Protein: FABH_CAMJJ
Sequence: MLKASLKSIASYIPEKILSNADLEKMVDTTDEWITRRTGIKERRIASENENTSDLGTKAALKAIERANLKPEDIDAILVATLSPDYFTMPSTACKIASNLGLVNISAFDISAACSGFIYLLEQAKALVESGLKKNVLIIGAEKTSSIMDYNDRSICILFGDGAGAGVVSLDNENHILDVHTASNGNYGDLLMTQRSQKSSLCQTLSMQMKGNEVFKIAVNTLSNDVVEILAKNNILAQEIDLFIPHQANLRIIKAVQEKLNLSDEKCVITVQKYGNTSAASIPMAMNDAYEEGRLKKGNLILLDAFGGGFTWGSALLKFGGENF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_AYWBP
Sequence: MGYHNVKYGKKAQRRNYSKTIYDVDLPNLIEIQNQSFDWFLKHGIKELLQDFCPIESYNGDLKIHFDDYFLTPPKYSIEETKIKDISYVAQLFVKTTLENVLTGETKQSNILLTELPLMTSTGTFIINGTERVVVSQIVRSASVYFAGNFDIKLNRTIYSGQVIPSRGAWIEYEEGSKEILYAKLDRSKKIPLSNFIYALGFDSKEAIENVFGKSAILDSVFDKETDMDSDNALVELYSKIRQGEKVPVDTARDFIRTRLFDQKKYDLAKVGRYKFNKKLDVLTRAENTYLACDFVNPENQEIMIAQDELLTKEKIAILKQNRHFLLQEIFDAKHNLENETDEEILAYKKYPQKNELFTKTNIINSRTGEVLVAKDTLVNDDIINHLRHNIHTLDEKVSKFFLGTKDIYQKEADRQGVFNEILEVYTSKDESGKLYNKVKLIGNDQRETKKHITLSDVIASINYYLNLYENVGTVDDIDHLGNRRLRLIGELLKNQFRIGLTRAEKNIKDMISTSKFGEVNGPGDLVNFTFLMSVIKTFFTNSRLSQFMDQINPLAELTQKRRVSALGIGGINRDRAGIEVRDVHNSHYGRLCPIETPEGPSIGLITSLSTYAKVNKYGFIQTPFFKVLQQDGKTTLSRDIDYLTADQEKEEIIASAGFVLDANNSFQDKKIIARSNGETGIFERNQITYADVSPKQIVSVATSSIPFLEHNDASRALMGANMQRQAVPLLIPESPIVGTGVEYRAAKDSGCLIIARESGFVTYVDAQKIIITKKPNQTVSLNGKTLYDTTQEFTYTQAKVLYENNHKEYQAEYTLINFAKSNQDTLVLQKPIVVLGEHINEGDILVSGPSTSQGELALGRNVTVAFMTWEGYNYEDAIIMSEELVKHDVYTSIHIDKYEVQTRELKKGSGQEEITREVPNVGADAIKNLDERGIIIPGSEVKEGDILVGKITPQGNIEPSPSEKLIQIVIGEKAREYKDSSLRVPFGEGGIVQSVHYFSRKNGDVLPAGVNENIRVFIAKKRKINEGDKMAGRHGNKGVISRILPKEDLPYMADGTPIDIMLNPLGVPSRMNIGQILEIHLGMAAKKLGIKVATPVFDGVNDYDLKEIMKEANLEPDGKMVLYDGRTGEPYDSRISVGVMYMVKLSHMVDDKLHARNVGPYTLVTQQPMGGKVQNGGQRFGEMEVWALYAYGAAHTLQEILTVKSDDIVGRNKTYSAIVQGTQLPKPSIPESFRVFIKELQSLGLYVELIKTDTKENEVNKSLIDYKKEGYN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TIG_EXIS2
Sequence: MTAKWEKQSGSLGVLTYEAPAEAFDKAVDQAFKKVVKTLNTPGFRKGKMPRAMFNKMYGEEALYQDALDILYQDTIEGAVVESGIEPIALDNIDVETLEKGKPVEFKITFVIEPDATLGEYKGLEYTAVETDVTDEDVDAELKTMQERGAELVVKEDGAIENGDTVVFDFAGFDGENQFDGGTAENYSLVIGSGNFIPGFEEQMVGLKSGEQKDIDVTFPEEYHEASLAGKPVVFKVTIHEIKAQELPELTDEFAKEMDEEVSSLDELKTKIRTRLENTRKQEADASMRDELVEAATKNATVDLPEVMVENEVERMVQEFTQRIQSQGIDLNMYFQLTGTTEEAMRTEMKEQAEERVKARLVLKQIVADEKIEVTEEEAQAELQSMSELYNIPADQLETMLAPQGGLDTLKGDLQFRKAIDVLVDNAKAK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CYB_HEXLI
Sequence: MTNIRKSHPLMKIINDALVDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTPDTLTAFSSVTHICRDVNYGWAIRYMHANGASIFFICLFIHVGRGLYYGSYTFLETWNIGVILLLTTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIMALAAVHLLFLHETGSNNPTGIPSNADKIPFHPYYTIKDILGVLLLMTMLLTLTLFAPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALIPMLHTSKQRSLMFRPLSQCLFWALIADLLTLTWIGGQPVEHPYIIIGQLASILYFLLILVLMPVAGIIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KHSE_PERMH
Sequence: MKVLKVKVPATTANLGAGFDTLGLALTLYNEFIVEEHDGVVIETEPKNEFLEIPENNLFIQVIKYACERRGKTFHGAKLKQINRVPVARGLGSSATAIVGAIVVSSAVSKTELTDDIFFDIAYRFEPHPDNLIPAWKGGFITALKDREKTYYNSIDFPEDIKAVVVIPEFELSTEKARSVLPERIPLRDGIFNVQRVSLFLSALQNRRYDLLRVAMEDRFHQPYRKKLIPNFDRVVQNGYDAGALGVSLSGAGSAILALADRNFEEIGKAMTEGFSEAGIRSEYKILDIDREGANLEILE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARO1_YEAS1
Sequence: MVQLAKVPILGNDIIHVGYNIHDHLVETIIKHCPSSTYVICNDTNLSKVPYYQQLVLEFKASLPEGSRLLTYVVKPGETSKSRETKAQLEDYLLVEGCTRDTVMVAIGGGVIGDMIGFVASTFMRGVRVVQVPTSLLAMVDSSIGGKTAIDTPLGKNFIGAFWQPKFVLVDIKWLETLAKREFINGMAEVIKTACIWNADEFTRLESNASLFLNVVNGEKNVKVTNQLTNEIDEISNTDIEAMLDHTYKLVLESIKVKAEVVSSDERESSLRNLLNFGHSIGHAYEAILTPQALHGECVSIGMVKEAELSRYFGILSPTQVARLSKILVAYGLPVSPDEKWFKELTLHKKTPLDILLKKMSIDKKNEGSKKKVVILESIGKCYGDSAQFVSDEDLRFILTDETLVYPFKDIPADQQKVVIPPGSKSISNRALILAALGEGQCKIKNLLHSDDTKHMLTAVHELKGATISWEDNGETVVVEGHGGSTLSACADPLYLGNAGTASRFLTSLAALVNSTPSQKYIVLTGNARMQQRPIAPLVDSLRANGTKIEYLNNEGSLPIKVYTDSVFKGGRIELAATVSSQYVSSILMCAPYAEEPVTLALVGGKPISKLYVDMTIKMMEKFGINVETSTTEPYTYYIPKGHYINPSEYVIESDASSATYPLAFAAMTGTTVTVPNIGFESLQGDARFARDVLKPMGCKITQTATSTTVSGPPVGTLKPLKHVDMEPMTDAFLTACVVAAISHDSDPNSANTTTIEGIANQRVKECNRILAMATELAKFGVKTTELPDGIQVHGLNSIKDLKVPSDSSGPVGVCTYDDHRVAMSFSLLAGMVNSQNERDEVANPVRILERHCTGKTWPGWWDVLHSELGAKLDGAEPLECTSKKNSKKSVVIIGMRAAGKTTISKWCASALGYKLVDLDELFEQQHNNQSVKQFVVENGWEKFREEETRIFKEVIQNYGDDGYVFSTGGGIVESAESRKALKDFASSGGYVLHLHRDIEETIVFLQSDPSRPAYVEEIREVWNRREGWYKECSNFSFFAPHCSAEAEFQALRRSFSKYIATITGVREIEIPSGRSAFVCLTFDDLTEQTENLTPICYGCEAVEVRVDHLANYSADFVSKQLSILRKATDSIPIIFTVRTMKQGGNFLDEEFKTLRELYDIALKNGVEFLDLELTLPTDIQYEVINKRGNTKIIGSHHDFQGLYSWDDAEWENRFNQALTLDVDVVKFVGTAVNFEDNLRLEHFRDTHKNKPLIAVNMTSKGSISRVLNNVLTPVTSDLLPNSAAPGQLTVAQINKMYTSMGGIEPKELFVVGKPIGHSRSPILHNTGYEILGLPHKFDKFETGSAQLVKEKLLDGNKNFGGAAVTIPLKLDIMQYMDELTDAAKVIGAVNTVIPLGNKKFKGDNTDWLGIRNALINNGVPEYVGHTAGLVIGAGGTSRAALYALHSLGCKKIFIINRTTSKLKPLIESLPSEFNIIGIESTKSIEEIKEHVGVAVSCVPADKPLDDELLSKLERFLVKGAHAAFVPTLLEAAYKPSVTPVMTISQDKYQWHVVPGSQMLVHQGVAQFEKWTGFKGPFKAIFDAVTKE
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLB1_PHRSO
Sequence: VSANDIKNVQDTWGKLYDQWDAVHASKFYNKLFKDSEDISEAFVKAGTGSGIAMKRQALVFGAILQEFVANLNDPTALTLKIKGLCATHKTRGITNMELFAFALADLVAYMGTTISFTAAQKASWTAVNDVILHQMSSYFATVA
What are the official names of this protein?
Globin-1, Globin I, Hb I.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: FERM1_PONAB
Sequence: MLSSTDFTSASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLQLVEQINISQDWSDFALWWEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVSDICKTLNIRRSEELSLLKPCGDYFKKKKKKDKNNKEPITEDILNLESSPTASVSSVSPGLYSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSSEALADMYQPRSLVDKAKLNAGWLDSSRSLMEQGIQEDGQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILLEEIDCTEEEMLIFAALQYHISKLSLSAETQDFTSESEVDEIEAALSNLEVTLEGGKADSLLEDITDIPKLADNLKLFRPKKLLLKAFKQYWFVFKDTSIAYFKNKELEQGEPLEKLNLRGCEVVPNVNVAERKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSSYRPEVLNILSFLRMKNRNSASQVASSPENMDMNPECFVSPRCAKKHKSKQLAARILEAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGIPVTTWRFTNIKQWNVSWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLDEDLFHKLTGGQD
What is the function of this protein?
Involved in cell adhesion.  Contributes to integrin activation.  When coexpressed with talin, potentiates activation of ITGA2B.  Required for normal keratinocyte proliferation.  Required for normal polarization of basal keratinocytes in skin, and for normal cell shape.  Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity).
What are the official names of this protein?
Fermitin family homolog 1, Kindlin-1, Unc-112-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the kindlin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with filamentous actin. Constituent of focal adhesions (By similarity). Localized at the basal aspect of skin keratinocytes, close to the cell membrane (By similarity). Upon TGFB1 treatment, it localizes to membrane ruffles (By similarity).
Protein: RF1_BRUAB
Sequence: MIALPQDRMDQLLKRFSMIESQMANNPDSDTYVKLASEYSELQDVVGKIRELSDARMEASDLAAMRDDASTDAEMRALAVEELPEVEKRIAVLEQDVQILLLPKDAADDKNAILEIRAGTGGLEATLFAGDLFRMYERYAAEKGWRVELVSASEGDAGGYKEIIATVSGKGVFSKLKFESGVHRVQRVPETEAGGRIHTSAATVAVLPEAEDIDIEIRNEDIRIDTMRASGAGGQHVNTTDSAVRITHIPTGIMVVQAEKSQHQNRARAMQILRARLYDMERQKAESERSQARRSQVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDRVMEGDLDELVDALISDHQTALLAELGEQP
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_BACSH
Sequence: MAQSHSSSVNYFGSVNKVVFEGKASTNPLAFKYYNPQEVIGGKTMKEHLRFSIAYWHTFTADGTDVFGAATMQRPWDHYKGMDLARARVEAAFEMFEKLDAPFFAFHDRDIAPEGSTLKETNQNLDIIVGMIKDYMRDSNVKLLWNTANMFTNPRFVHGAATSCNADVFAYAAAQVKKGLETAKELGAENYVFWGGREGYETLLNTDLKFELDNLARFMHMAVDYAKEIEYTGQFLIEPKPKEPTTHQYDTDAATTIAFLKQYGLDNHFKLNLEANHATLAGHTFEHELRMARVHGLLGSVDANQGHPLLGWDTDEFPTDLYSTTLAMYEILQNGGLGSGGLNFDAKVRRSSFEPDDLVYAHIAGMDAFARGLKVAHKLIEDRVFEDVIQHRYRSFTEGIGLEITEGRANFHTLEQYALNNKTIKNESGRQERLKAILNQYILEV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED6_CAEEL
Sequence: MMPRMGPPAAARQDNPLHVSFRNPQWPPNFINKDNVLDYFCNQANAFYEMNSCNQQIRMQNIVNRTVEECLRTMPGIQYVLWYSQPPLFIICKQRRNNVTNVSPIAYYYVINGSVHQAPDMYSLVQSRLLGALEPLRNAFGEVTNYSRYNTAKGYYWEFKNKPNVKKREEEKKEDEEEKLEDRSTNFQKTRTMMLLNQLFSEMPAEDALEREEKEEVEEEEEETLKTEEPTTSTDEPKFAEPTARTTSKQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).  Acts to repress beta-catenin target genes.  Required for asymmetric division of T-cells and for gonad and germ cell development.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 6, CeMED6, Mediator complex subunit 6, c-MED6, MED-6.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPD_CITBB
Sequence: MIRKAIARVVERQDLSEAEMIEVMDQVMSGGATPAQIASFITALRMKGETVDEITGAARVMRDRALPIRVGKSVLGIDRDDINLDRETILDTCGTGGSGTNSFNISTTVAFIVSACGVKVAKHGNRAVSSSCGSADVLEALGVNLDVTPDVVERSIAQIGIGFLFAPALHGAMKHAIGPRREIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEKLAQVLKKLGCRSGFVVHGCDGMDEITLTGESTVAEITADGVKLYKVTPEQFGLERAPLAELHGGDALGNAVIVRDILSGKDGAKRRIVLLNAGYALVATGKAKDVAEGIRLAAETIDSGAAMKQLERLVALTNEAE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: DLX3_AMBME
Sequence: MSTILTDLSSSLSCHAASKDSPTLPESSATDLGYYSTHGGTHSPHDYFQSQPYPQPINHHYPYHQFNLNGLGGPGTYSPKSDYPYGGSYRQYGHYRESAMAVQEPVSVKEEPEPEVRMVNGKPKKIRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPGMEHSPDNSDSMACNSPASPPVWDSNPPSRVPHPQAQPLPHNSSPSYLEDYNPGTTMNRTWRGTPAAAQLDAPYPSGTGSVLAGCWWKN
What are the official names of this protein?
Homeobox protein DLX-3.
What is the protein family that this protein belongs to?
Belongs to the distal-less homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL10E_HALLT
Sequence: MSDKPASMYRTIDKPSYTRREYITGIPGSKIAQHNMGDLSAEPDDYPVQISLRVEEELQIRHGSLESSRLSANRHLIKELGEGNYKMTLRKFPHQVIRENKQATGAGADRVSDGMRQAFGKPVGTAARLNKDDIVFTAYCDVEQASVVKEAFRRAYNKLSPPCRITVDRGEELLVS
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RANSM_POLLE
Sequence: AYACSFPPSEIPGSKECLAEALQKHQGFKKKSYALICAYLNYKEDAENYERAAEDFDSAVKCTGCKEGVDLHEGNPELIEEGFEKFLASLKIDRKALGSLCTLFQKLYAIPHN
What are the official names of this protein?
Ranasmurfin, RSF-1.
What are the subcellular locations of this protein?
Secreted.
Protein: UL04_HCMVM
Sequence: MMLRTWISLPMVLLDAYCFCIFVSCSISTTTAPVEWKSPDRQIPMNITCANYSGTVNGNVTFRGLQNKTEDFLHWLLGWGHKSICSFFPKLQGNKEQHYMYGITNLTYNCTYDRLTLLNLTTENSGKYYFKREDVNSTFYYSCYNLTVT
What are the official names of this protein?
Envelope glycoprotein UL4.
What is the protein family that this protein belongs to?
Belongs to the RL11 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein.
Protein: CAPSD_RMVHR
Sequence: MSYNITNSNQYQYFAAVWAEPTPMLNQCVSALSQSYQTQAGRDTVRQQFANLLSTIVAPNQRFPDTGFRVYVNSAVIKPLYEALMKSFDTRNRIIETEEESRPSASEVANATQRVDDATVAIRSQIQLLLNELSNGHGYMNRAEFEAILPWTTAPAT
What is the function of this protein?
Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ISPF_SHEB5
Sequence: MKIRIGHGFDVHKFGAARPLILCGVEVPYETGLIAHSDGDVVLHAISDAILGALALGDIGKHFPDTDTAYKGADSRVLLRHCYALARAKGFVLGNLDVTIIAQAPKMAPHIEAMRQILAADLTSELDDINVKATTTEQLGFTGRKEGIAVEAVVLMTRKHD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RK22_CUSEX
Sequence: MINTKPPEIYALGQHISMSADKARRIIDRIRGRSYEETLLILELMPYRAAYPIFKLVYSAASNASYTLASNEANLVIIKAEVNEGPAIKKLKPRARGRCYPIKRPTCHITIVLKDISFYDSDSESVELNLLKKAR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid.
Protein: RL22_PSYIN
Sequence: MEALAKHLYARSSAQKARLVADQVRGLPVEKALELLSYSPKKAAVLIKKVVDSAIANAEHNEGADIDELVITKICVDEGPTMKRIMPRAKGRADRIMKRSCHITVVVSDRG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL21_SHEB9
Sequence: MYAVFQSGGKQHRVAEGHTVRLEKLEVATGETIEFDQVLLIADGETVHVGAPLVAGGKVVAEVVSHGRGDKVTIVKFRRRKHHDKKMGHRQWFTEVKITAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ISPE_HALH5
Sequence: MKQSVKAPAKINLSLDVLHKRPDGYHEVDMIMTTVDLADRIDLTLREDGLISVDVSEGFVPNDEKNLAYQAAALLKARYHVNEGVSIYITKRIPVAAGLAGGSSDAAATLRGLNDLWQLGLSLDELAVLGAEIGSDVSFCVYGGTARATGRGEIIERIASPPPCWVILAKPPIGVSTADVYKRLNVSAIDHPTTEHMIAAIEGKDFDGICHHLHNVLESVTLDLYPEVRNIKEQMKRFGADGVLMSGSGPTVFGLVSKESRVQRIYNGLRGFCHQVYAVRIIGSAGS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: FUR_ECOLI
Sequence: MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.  Regulates the expression of several outer-membrane proteins including the iron transport operon.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POLS_IBDVE
Sequence: MTNLQDQTQQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSIVGAHYTLQSNGNYKFDQMLLTAQNLPASYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMVATCDSSDRPRVYTITAADNYQFSSQYQTGGVTITLFSANIDAITSLSVGGELVFKTSVQSLVLGATICLIGFDGTAVITRAVAANNGLTAGIDNLMPFNLVIPTNEITQPITSIKLEIVTSKSDGQAGEQMSWSASGSLAVTIHGGNYPGALRPVTLVAYERVATGSVVTVAGVSNFELIPNPELAKNLVTEYGRFDPGAMNYTKLILSERDRLGIKTVWPTREYTDFREYFMEVADLNSPLKIAGAFGFKDIIRAIRRIAVPVVSTLFPPAAPVAHAIGEGVDYLRGDEAQAASGTARAASGKARAASGRIRQLTLAADKGYEVVANLFQVPQNPVVDGILASPGILRGAHNLDCVLREGATLFPVVITTVEDAMTPKALNNKMFAVIEGVREDLQPPSQRGSFIRTLSGHRVYGYAPDGVLPLETGRDYTVVPIDDVWDDSIMLSKDPIPPIVGNSGNLAIAYMDVFRPKVPIHVAMTGALNACGEIEKISFRSTKLATAHRLGLKLAGPGAFDVNTGPNWATFIKRFPHNPRDWDRLPYLNLPYLPPNAGRQYHLAMAASEFKETPELESAVRAMEAAANVDPLFQSALSVFMWLEENGIVTDMANFALSDPNAHRMRNFLANALQAGSKSQRAKYGTAGYGVEARGPTLEGAQREKDTRISKKMETMGIYFATQEWVAFNRHRRPSPGQLKYWQNTREIPDPNEYYLDYVHAEKSRLASEEQILRAATSIYGAPVQAEPLQAFIDEVAKVYEINHGRGPNQEQMKDLLLTAMEMKHRNPRRAPPKPKPKPNAPTQRPPGRLGRWIRTVSDEDLE
What is the function of this protein?
Structural peptide 4 is a small peptide derived from pVP2 C-terminus.  It is essential for the virus viability (By similarity).
What are the official names of this protein?
Structural polyprotein, PP.
What are the subcellular locations of this protein?
[Capsid protein VP2]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein VP3]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 1]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 2]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 3]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 4]: Virion. Host cytoplasm.
Protein: COX2_PROTA
Sequence: MAYPVQLGFQDAASPIMEELLYFHDHTLMIVFLISSLVLYIISLMLTTKLMHTSTMDAQEVETVWTILPAIILILIALPSLRILYMMDEITTPSLTLKTMGHQWYWSYEYTDYEDLSFDSYMVPSSDLKPGELRLLEVDNRIVLPTELSIRMLISSEDVLHSWAVPSLGVKTDAIPGRLNQATLMTSRPGIYYGQCSEICGANHSFMPIVLELVPLKHFEEWLLSMF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EFTU_CAMJE
Sequence: MAKEKFSRNKPHVNIGTIGHVDHGKTTLTAAISAVLSRRGLAELKDYDNIDNAPEEKERGITIATSHIEYETDNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFMNKADMVDDAELLELVEMEIRELLSSYDFPGDDTPIISGSALKALEEAKAGQDGEWSAKIMDLMAAVDSYIPTPTRDTEKDFLMPIEDVFSISGRGTVVTGRIEKGVVKVGDTIEIVGIKDTQTTTVTGVEMFRKEMDQGEAGDNVGVLLRGTKKEEVIRGMVLAKPKSITPHTDFEAEVYILNKDEGGRHTPFFNNYRPQFYVRTTDVTGSIKLADGVEMVMPGENVRITVSLIAPVALEEGTRFAIREGGKTVGSGVVSKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.