PharMolix/UniProtQA huggingface dataset:
Protein: SYC_AGRRK
Sequence: MGTEPQLKLYNTLTREKVDFQPIDRENVRLYVCGPTVYDFAHIGNARPAIVFDVLFRLLRQVYGENHVTYARNITDVDDKINARALRDHPGLPLNEAIRLVTEKTETQYYQDTTALGCLEPTVQPRATDNIAQMIEIIEKLIARGHAYQAAGEVLFDTKSMADYGQLSKRNLDEQQAGARIAVDAHKKSPGDFVLWKLSAENEPGWESPWGRGRPGWHIECSAMSGRYLGDVFDIHGGGLDLIFPHHENEIAQSRCAHGTDVMANVWMHNGFLQVEGRKMSKSEGNFVTIYELLQTEKLGGRTWPGAVLRLAMLMTHYREPIDFSVKRLEEAERLLAKWPAADIGNAKPDATVLVALADDLNTVVAIQALHALAQAANADASILPVFAASAALLGLLPEKVEMDDAVASEIDARVRARLELLKAKNFAEADKIRDTLLAEGIQLKDGKDPATGERITTWEVKR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_HALOH
Sequence: MKILVLNSGSSSLKYQLFDMEKETVMAKGVVQRIGIDNSFLEHENYRGEETTIETDIPDHNRGIQLVIDTLQDEKYGVLNNMEEIDAVGHRVVHGGEKFAESTLITDEVIKQIEEVSELAPLHNPHNLTGIRVCSKLMPGIPQVAVFDTAFHQTMPRKAYVYALPYEYYEKYGIRRYGFHGTSHKYVAERAARLMDKPLEELKIITCHLGNGASVAAIDAGKSVDTSMGLTPLEGLVMGTRCGDIDPAIIPFIMDKENLDIKEVDNVLNKKSGLYGVSGISNDSRDVEEASKDGNERATIALEIFKYRVKKYIGAYTAVMGGVDAVVFTAGIGENAIEMRESIVEELGFLGVKLDRDANNNRGKEIEISTKDSRTKIFVIPTNEELVIARDTARIVES
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_THEGJ
Sequence: MDWNGRDVISIRDFSKSDIEFVLKVAERLEEELREKGSLEYARGKILATLFFEPSTRTRLSFESAMHRLGGSVIGFSSASSTSVRKGESLADTIRTVEQYSDVIVIRHPMEGAARLAAEVAEVPVINAGDGSNQHPTQTLLDLYTIKRAFGKIDGLTIGLLGDLKYGRTVHSLAEALAFYDVELYLISPELLRMPKHIVEELRERGVKIHETTDLEGAIPELDVLYVTRIQRERFPDEEEYLKVKGSYQVNCKLLKNAKETLKVMHPLPRVDEIHPEVDKSEHALYFRQVFSGVPVRMALLGLTLGVL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ATPA_CITSI
Sequence: MTTIKADEISNIIRERIEQYNREVKIVNIGTVLQVGDGIARIYGLDEVMAGELVEFEEGTIGIALNLESTNVGVVLMGDGLMIQEGSSVKATGKIAQIPVSEAYLGRVINALAKPIDGRGEISASESRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQQGQNVICVYVAIGQKASSVAQVVNTFQERGAMDYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDPSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLGSQLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQAQAAPLTVEEQIMTIYTGTNGYLDSLEIGQVRKFLVELRTYLKTNKPQFQEIISSTKIFTEEAEALLQEAIQEQKERFLLQEQF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PSAB_SYNS3
Sequence: MATKFPSFSQGLAQDPTTRRIWYGIATAHDFESHDGMTEEKLYQKLFSTHFGHLAIIGLWVSGNLFHIAWQGNFEQWVSDPLHVRPIAHAIWDPHFGQGAIDAFTQAGASSPVNIAYSGLYHWFYTIGMTTNAELYQGSIFMMILSAWALFAGWLHLQPKFRPSLAWFKNAESRLNHHLAVLFGFSSIAWTGHLVHVAIPESRGQHVGWDNFLSVMPHPAGLGPFFTGNWGVYAQNPDTTGQIFGTAEGSGTAILTFLGGFHPQTEALWLTDIAHHHLAIGVIFVIAGHMYRTNFGIGHSIREILEAHNPPTGTPGDLGAGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYAMPSYAFIAKDYTTQAALYTHHQYIAIALMCGAFAHGAIFFIRDYDPEANKDNVLGRMLEHKEAIISHLSWVSLFLGFHTLGLYVHNDVVVAFGTPEKQILVEPVFAQFVQAASGKAIYGFDVLLANAGGAAANANAAYMGGWMDAINGVRGSNDLFLPIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWALNTVGWVTFYWHWKHLAIWQGNVAQFNESSTYLMGWFRDYLWLNSSQLINGYNPFGSNNLAVWSWMFLFGHLVWATGFMFLISWRGYWQELIETIVWAHERSPIANMMGWRDKPVALSIVQARVVGLAHFTVGYVLTYGAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: EIF3I_CRYNJ
Sequence: MKPIILQGHERSLNQIVFNSEGDLLFSASKDSVVNAWYTSNGERLGTYGGIKGGDGHNGSVWTVAVDSQTRFLLTGGADNAMKLWEVKTGECLYTWEFLTAVKRVAWNEDDDMFLSITEQRSGQPSVIRIFSINREDPRSQSTTPITEMRLSGSRATVAIWAPLSDYIITGHESGKIAKYDVKTGEEVQAVEDEHSALISDIQLSPDGTYFITASKDKTARLWDIETLEVMKVYTTETPVNSAVITPDRPYIILGGGQDAMNVTTTSQRAGKFESRFFHKLFEEEVGRVKGHFGPINTLSVHPQGRAYASGAEDGFVRVHWFEESYFRSRPFGDLEPEPEV
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 39 kDa subunit homolog, eIF-3 39 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGCZ_ECOLI
Sequence: MIKKTTEIDAILLNLNKAIDAHYQWLVSMFHSVVARDASKPEITDNHSYGLCQFGRWIDHLGPLDNDELPYVRLMDSAHQHMHNCGRELMLAIVENHWQDAHFDAFQEGLLSFTAALTDYKIYLLTIRSNMDVLTGLPGRRVLDESFDHQLRNAEPLNLYLMLLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKAANDEEACRAGVRICQLVDNHAITHSEGHINITVTAGVSRAFPEEPLDVVIGRADRAMYEGKQTGRNRCMFIDEQNVINRV
What is the function of this protein?
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (PubMed:18713317, PubMed:19460094, PubMed:20582742).  May act as a zinc sensor that controls, via c-di-GMP, post-translational events (PubMed:23769666).  Overexpression leads to a strong repression of swimming; swimming returnes to normal when residues 206-207 are both mutated to Ala.  Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di-GMP levels in vivo.  Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors.  The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle.  C-di-GMP is a second messenger which controls cell surface-associated traits in bacteria (PubMed:19460094).
What are the official names of this protein?
Diguanylate cyclase DgcZ, DGC, Zinc-sensory diguanylate cyclase.
Protein: BSHC_BACVZ
Sequence: MQLTELSIKSQNKFVQHYIDGENMSSFFDYDIHSEDVWQKRLHDLSSQPFAREELADYLSSYHEKFHSAAMQASIEKLRDPKSAAVVGGQQAGLLTGPLYTIHKIISIIVLARQQEEALQIPVVPIFWVAGEDHDLEEINFVHTSTENKGPVKQKLPQSYWKKTSAAKTELDQEKCAAWIDEVFAAFEETDHTNTLLQNVKRCLRSSETFTDFFELLIADLFQEEGLILMNSGDPGIKKLETGMFQQILKHNHELAKAVSDQQRLMREAGYHPIIESDKDQANLFYEHEGERFLIEKENGVFVIKELDLKWTNDELHTHMEEKPECFSNNVVTRPLMQEFLIPTLAFIAGPGEINYWGELKRAFSLMGFRMTPVVPRLNITILERHIEKKLSERNIPLQEAIEHGTGHLKDTYFEEQIPEEFSSVMEQAKSQIEAVHKRARDEALKVDSSLEPLLQKNAAFIQDQLLFLERTVTKRIEEKEGFVLRDYERIQNSIRPLGAPQERIWNVMYYLNRYGPKFFTTFKHLPFSFQNQHQIVKL
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: RLMI_SALCH
Sequence: MTESTFPQYPRLVLSKGREKSLLRRHPWVFSGAVSRLEGKANLGETIDIVDHQGKWLARGAWSPASQIRARVWTFDKAESIDIAFFTRRLRQAQQWRDWLAKKDGLDSYRLIAGESDGLPGVTIDRFGHFLVLQLLSAGAEYQRAALISALQTCYPDCAIYDRSDVAVRKKEGMALTQGPVTGELPPALLPIEEYGMKLLVDIQGGHKTGYYLDQRDSRLATRRYVENQRVLNCFSYTGGFAVSALMGGCRQVVSVDTSQDALDIARQNVELNQLDLSKAEFVRDDVFKLLRAYREHGEKFDVIIMDPPKFVENKSQLMGACRGYKDINMLAIQLLNPGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_FLAJ1
Sequence: MINFNYETEFSLDNEQAFTDWLSAVIVSEEKNEGEINYIFCDDEYLHKINVEYLNHDTLTDIISFDYTVGNEISGDIFVSVERVEDNAKDFNVSFEEELKRVLAHGILHYCGYKDKSDADAELMRSKEDEKIAMFHVEQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPA3_DICDI
Sequence: MVLPLLKVGSLLIKSLAKPLSKQIKIRASKSPIFHDRVVRGARLWHKLDLKLTKFNGDTTRKPVDLNVNAAIDLGTEIVSEAFLLSVAIGLLLYETSRSSEKDKKKEEALQNRFKNLEEKLEVQQETINNLTNVIEAIQSSNPNLNIYIDPNQSTKSSIAEYINTHNIKLNSLKNAQTENDYKSISSEGIPNKRISNVN
What are the official names of this protein?
OPA3-like protein.
What is the protein family that this protein belongs to?
Belongs to the OPA3 family.
Protein: BCAT7_ARATH
Sequence: MAPSVHPSSSPLFTSKADEKYANVKWDELGFALVPTDYMYVAKCKQGESFSTGEIVPYGDISISPCAGILNYGQGLFEGLKAYRTEDGRITLFRPDQNAIRMQTGADRLCMTPPSPEQFVEAVKQTVLANNKWVPPPGKGALYIRPLLIGTGAVLGVASAPEYTFLIYTSPVGNYHKASSGLNLKVDHNHRRAHFGGTGGVKSCTNYSPVVKSLIEAKSSGFSDVLFLDAATGKNIEEVSTCNIFILKGNIVSTPPTSGTILPGITRKSICELARDIGYEVQERDLSVDELLEAEEVFCTGTAVVIKAVETVTFHDKRVKYRTGEEAFSTKLHLILTNIQMGVVEDKKGWMMEIDHLVGTDSFPDET
What are the official names of this protein?
Putative branched-chain-amino-acid aminotransferase 7, Atbcat-7.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: TM2D2_HUMAN
Sequence: MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSQNATAEPELTSAGAAQPEGPGGAASWEYGDPHSPVILCSYLPDEFIECEDPVDHVGNATASQELGYGCLKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY
What are the official names of this protein?
TM2 domain-containing protein 2, Beta-amyloid-binding protein-like protein 1, BBP-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TM2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DNLJ_STRPS
Sequence: MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELETAYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHPTYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDITVRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQEASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVVIKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIPTNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFAANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGSKVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETGVNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVVVGADAGSKLQKAQELGIQVRDEAWLESL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: AK_MYCTO
Sequence: MALVVQKYGGSSVADAERIRRVAERIVATKKQGNDVVVVVSAMGDTTDDLLDLAQQVCPAPPPRELDMLLTAGERISNALVAMAIESLGAHARSFTGSQAGVITTGTHGNAKIIDVTPGRLQTALEEGRVVLVAGFQGVSQDTKDVTTLGRGGSDTTAVAMAAALGADVCEIYTDVDGIFSADPRIVRNARKLDTVTFEEMLEMAACGAKVLMLRCVEYARRHNIPVHVRSSYSDRPGTVVVGSIKDVPMEDPILTGVAHDRSEAKVTIVGLPDIPGYAAKVFRAVADADVNIDMVLQNVSKVEDGKTDITFTCSRDVGPAAVEKLDSLRNEIGFSQLLYDDHIGKVSLIGAGMRSHPGVTATFCEALAAVGVNIELISTSEIRISVLCRDTELDKAVVALHEAFGLGGDEEATVYAGTGR
What is the function of this protein?
Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.
What are the official names of this protein?
Aspartokinase, Aspartate kinase, ASK.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: PSAJ_CUSEX
Sequence: MRDFKTYLSAAPVLSTLWLGALAGLLIEINRFFPDALTFPFF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: YP238_YEAST
Sequence: MLELALGVPSLLSASTLSRPALASSFSNASTLLSFVFFFFFFKDSSPKASAMSSVGSFSASASAETLLDFFFFFFNPANKSSPEPFSLPFTAASKSSGITFLVFFFFFSAGSNPNSAAKSEDISCVLII
What are the official names of this protein?
Putative uncharacterized protein YPL238C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TIF6A_ORYSI
Sequence: MERDFLGAIGRKEEAAGKPEEHSDYRGGGGGASAAMQWQFPATKVGAASSAFMSFRSSAAAAREEDPKEAAVFDRFSLSGFRPPPRPSPGDAFDGAAAMKQRQFGFNGRQQYAAAAQHGHREQGVDSYGVAAPHHFPSPSPSPRHPVPFGHANPMLRVHSLPNVAGGSPYRNQSFSVGNSVAGSTVGVYGGPRDLQNPKVTQMTIFYDGLVNVFDNIPVEKAQELMLLASRASIPSPPSAARKSDSPISAAAKLTVPEALPARQIVVQKPEASVPLVSGVSNPITIVSQAVTLPKSSSSSNDSAGPKSGGLPLAVTPLSQASPSQPIPVATTNASAIMPRAVPQARKASLARFLEKRKERVSSVAPYPSSKSPLESSDTIGSPSTPSKSSCTDITPSTNNCEDSLCLGQPRNISFSSQEPPSTKLQI
What is the function of this protein?
Repressor of jasmonate responses.
What are the official names of this protein?
Protein TIFY 6a.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HDAC8_HUMAN
Sequence: MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
What is the function of this protein?
Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (PubMed:10748112, PubMed:10922473, PubMed:10926844, PubMed:14701748, PubMed:28497810).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (PubMed:10748112, PubMed:10922473, PubMed:10926844, PubMed:14701748).  Histone deacetylases act via the formation of large multiprotein complexes (PubMed:10748112, PubMed:10922473, PubMed:10926844, PubMed:14701748).  Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin (PubMed:22885700).  May play a role in smooth muscle cell contractility (PubMed:15772115).  In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones (PubMed:28497810).
What are the official names of this protein?
Histone deacetylase 8, HD8, Protein deacetylase HDAC8, Protein decrotonylase HDAC8.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Excluded from the nucleoli (PubMed:10748112). Found in the cytoplasm of cells showing smooth muscle differentiation (PubMed:15772115, PubMed:16538051).
Protein: CYSN_SODGM
Sequence: MNNAIAQQIAEQGGVEAYLHAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSTLHTDSKRLGTQGDKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDVAILLIDVRKGVLDQTRLHSFISTLLGIRHLVVAVNKMDLVAFDEQIFQGIRQDYLRFAEQLPVDLDITFVPLSALEGDNVAALGKAMPWYNGPTLLDVLETVEVINLNEQQPARFPVQYVNRPNLDFRGYAGTVAAGVLRVGQAVKVLPSGVTSTISRIVTFDGDLTEAWAGEAVTLVLKDEVDISRGDLLVDAGETLTEVQNAQVDVVWMTEQPLVAGQSFDIKIAGKKTRARVDNIQYQVDINTLTQRVADSLPLNGIGLVELAFDEPMILDKYADNPTTGGMIFIDRLSNVTVGAGMVRQPLQDVYREPGAYGEFELALNALVRRHFPHWGARDLLGGK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: HDA_YERP3
Sequence: MLVEVLLNTPAQLSLPLYLPDDETFASFYPGENPSLLAAIQSAVHQPHGSYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVPLDKRAYFIPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILSL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: NDBAA_ARATH
Sequence: MGRKKGLPEFEESAPDGFDPENPYKDPVAMVEMREHIVREKWIHIEKAKILREKVKWCYRVEGVNHYQKCRHLVQQYLDATRGVGWGKDHRPISLHGPKPVAVEEAE
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10-A.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB10 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GG_HHV2H
Sequence: MHAIAPRLLLLFVLSGLPGTRGGSGVPGPINPPNSDVVFPGGSPVAQYCYAYPRLDDPGPLGSADAGRQDLPRRVVRHEPLGRSFLTGGLVLLAPPVRGFGAPNATYAARVTYYRLTRACRQPILLRQYGGCRGGEPPSPKTCGSYTYTYQGGGPPTRYALVNASLLVPIWDRAAETFEYQIELGGELHVGLLWVEVGGEGPGPTAPPQAARAEGGPCVPPVPAGRPWRSVPPVWYSAPNPGFRGLRFRERCLPPQTPAAPSDLPRVAFAPQSLLVGITGRTFIRMARPTEDVGVLPPHWAPGALDDGPYAPFPPRPRFRRALRTDPEGVDPDVRAPRTGRRLMALTEDTSSDSPTSAPEKTPLPVSATAMAPSVDPSAEPTAPATTTPPDEMATQAATVAVTPEETAVASPPATASVESSPLPAAAAATPGAGHTNTSSASAAKTPPTTPAPTTPPPTSTHATPRPTTPGPQTTPPGPATPGPVGASAAPTADSPLTASPPATAPGPSAANVSVAATTATPGTRGTARTPPTDPKTHPHGPADAPPGSPAPPPPEHRGGPEEFEGAGDGEPPEDDDSATGLAFRTPNPNKPPPARPGPIRPTLPPGILGPLAPNTPRPPAQAPAKDMPSGPTPQHIPLFWFLTASPALDILFIISTTIHTAAFVCLVALAAQLWRGRAGRRRYAHPSVRYVCLPPERD
What is the function of this protein?
Chemokine-binding protein that inhibits neutrophils' chemotaxis.
What are the official names of this protein?
Envelope glycoprotein G, gG, gG-2.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein G family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: MT872_AERPE
Sequence: MSRYSTISLFSGAGGLDLGFVQSGRFRIVFANEILLPAAVTYSRNLGLRLEVCGDEPRVEAQPGTIMACDVAKLDFTGLSGVDADVIIGGPPCQDFSIVRGPDWDRRGINVKRGRLYAHFVRALASLQPKAFVFENVPGLVSANRGLAYKVILEDFARLSIRWDEIKRIVSSNGNGGKVEGYEIVFTGIVDFSKLGVPQKRERLVIIGLRKDLAGGGFETISRLRARIDHVLSGKRWLLHRYPLTPIEVFEGQPLDRLGDKYKEVMLKWEGVWDEVGTERAFEWKRRVWDRLTFDIISDYLSFNGIKHADKQELEEALMQHEVLLKELGYYGRPVYSLKLPDSTTEPPYEGKAVVERMKRIPPDENHEFVRGTRWEVEGRGISLVYRRIHPLKPSYTVVAYGGGGTHGYHYDRDRATLTLRERARLQTFPDSFLFYGKKPEIRAQIGEAVPPLAAKRIAEALAEVLDAV
What is the function of this protein?
Cytosine methylase that recognizes the double-stranded sequence 5'-GC(A/T)GC-3', methylates C-5 position of the second cytosine on both strands, and protects the DNA from cleavage by the ApeKI endonuclease.
What are the official names of this protein?
DNA (cytosine-5-)-methyltransferase M.ApeKI, M.ApeKI, Cytosine-specific methyltransferase ApeKI, Modification methylase ApeKI, Type II methyltransferase M.ApeKI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: HSP1_DESRO
Sequence: MARYRCCRSPSRSRCRRRRRRCRRRRRRCCRRRRRVCCRRYTVRCRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TCPI_VIBC3
Sequence: MIKKIISVFLLLACIITSAFTAFFYHSKLSDQTKSISSLSSQQAQERLQSYQDSLDFYKKLNISLSVAIANSLRDKAVEELNAIALRIQENHGFIGVTFASLDGTMFTDIGTLDWNAKTLRRDWFVKTVELGTKHYTAFDIDKTTGQHVLTIATPVYVGNDIVGSVALDIAGDQIASPNGSGMFMMTDRNFNVFASDLTHSTLIGKDLTKEKPLFKNLVSGQYVTFSDADSHWFAVSQTEIDGENKLFTIIDIQQIVQTYKRDIQLIIAGFSGFSCVMLIGLYWVLSKELSGVRQIREWILSLSDGQIKERRPIKFHNELDTIAQSLENLQFRLLDVVRNSHRTMNDLSIKQTDITYSIEGNTNNSQQELGLIEQVATATTQLSCTSFDVMQQAQSAELNAETAQKLIAESHDIIDSSSKQTEMVTLSIHESQQIINQLREFSDNISSVTDVINNISDQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAVKTQQSTIDIQGIILKLQEQSQLADQVMTRNVSLIHETQVANRALIASFNLISDKVLEISNINSIVSTAANEQKIVTEDVAKQMEDIRYLVQENLSAMERTKQANQNISDLTTNLNDALSFFKIELTS
What is the function of this protein?
May function as an environmental regulator of TCP biogenesis.  Negatively regulates the synthesis of the major pilin subunit of TCP (TcpA).
What are the official names of this protein?
Toxin coregulated pilus biosynthesis protein I, TCP pilus biosynthesis protein TcpI.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.