PharMolix/UniProtQA huggingface dataset:
Protein: CNDP1_HUMAN
Sequence: MDPKLGRMAASLLAVLLLLLERGMFSSPSPPPALLEKVFQYIDLHQDEFVQTLKEWVAIESDSVQPVPRFRQELFRMMAVAADTLQRLGARVASVDMGPQQLPDGQSLPIPPVILAELGSDPTKGTVCFYGHLDVQPADRGDGWLTDPYVLTEVDGKLYGRGATDNKGPVLAWINAVSAFRALEQDLPVNIKFIIEGMEEAGSVALEELVEKEKDRFFSGVDYIVISDNLWISQRKPAITYGTRGNSYFMVEVKCRDQDFHSGTFGGILHEPMADLVALLGSLVDSSGHILVPGIYDEVVPLTEEEINTYKAIHLDLEEYRNSSRVEKFLFDTKEEILMHLWRYPSLSIHGIEGAFDEPGTKTVIPGRVIGKFSIRLVPHMNVSAVEKQVTRHLEDVFSKRNSSNKMVVSMTLGLHPWIANIDDTQYLAAKRAIRTVFGTEPDMIRDGSTIPIAKMFQEIVHKSVVLIPLGAVDDGEHSQNEKINRWNYIEGTKLFAAFFLEMAQLH
What is the function of this protein?
Catalyzes the peptide bond hydrolysis in Xaa-His dipeptides, displaying the highest activity toward carnosine (beta-alanyl-L-histidine) and anserine (beta-alanyl-3-methyl-histidine).
What are the official names of this protein?
Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Secreted.
Protein: MTNA_CHLAA
Sequence: MELRTVWWENDAVCLIDQRKLPHTMEVVRCTDLAAVAYAIRSMQVRGAPAIGCTAAYGMALVAQQSVALTPSALLTELVQAKATLDSQRPTAVNLAWATSRMLRRAEAVASEGVEAIKHALHAEAEAIFAEDLAMCHAIGEHGASLIPPRGHVLTHCNAGGLATAGYGTALAPIRTAFAQGRPVHVFVDETRPFLQGARLTAWELLQAGIPQTLITDNMAAFMMQRGQIDCVIVGADRIAANGDVANKIGTYGLAVLARYHNIPFYVAAPSSTIDLATASGADIPIEERDPAEVTHIAGVAIAPQGVRAAHPAFDVTPNELVTAIITERGIVRPPYLAALRQLESGR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: EFTU_PROM9
Sequence: MAREKFERNKPHVNIGTIGHVDHGKTTLTAAITNVLAKKGQAQAQDYGDIDGAPEERERGITINTAHVEYETEGRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGPMAQTKEHILLAKQVGVPALVVALNKCDMVDDEEIIELVEMEIRELLDSYDFPGDDIPIVQVSGLKALEGDSTWESKIEELMTAVDASIPEPEREVDKPFLMAVEDVFSITGRGTVATGRIERGKVKVGEEVEIVGIRDTRLTTVTGVEMFRKLLDEGMAGDNVGLLLRGVQKEDIERGMVLVKKGSITPHTQFEGEVYVLKKEEGGRHTPFFAGYRPQFYIRTTDVTGQITAFTSDDGSNVEMVMPGDRIKMTGELICPVAIEQGMRFAIREGGRTIGAGVVSKILK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC13_MAGO7
Sequence: MIHDAVLDYYGRRLATCSSDRTIKIFEVEGETHRLTETLKGHEGAVWCVAWAHPKYGNILASSGYDGKVFIWREQGGAWQKIFDFALHKASVNIVSWSPHESGCLLACASSDGHVSVLEFKDNSFDHQTFLAHGQGVNSVSWAPSTAPGSIISTNATPAAQRRFVTGGSDNTLKIWSWDAASAQYRCEEGGVLSGHTDWVLDVDWSPTVLQKSYIASASQDRTVRIWTSDSSNPGVWQSRVLKEFDTTVWRVSWSLSGNVLAVSSGDNKVTLWKENLKGEWACVNSLED
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: WNT4_HUMAN
Sequence: MSPRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRALVPRNAQFKPHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHTCR
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors (Probable).  Plays an important role in the embryonic development of the urogenital tract and the lung (PubMed:15317892, PubMed:16959810, PubMed:18179883, PubMed:18182450).  Required for normal mesenchyme to epithelium transition during embryonic kidney development.  Required for the formation of early epithelial renal vesicles during kidney development (By similarity).  Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries (PubMed:15317892, PubMed:16959810, PubMed:18182450).  Required for normal down-regulation of 3 beta-hydroxysteroid dehydrogenase in the ovary (PubMed:15317892, PubMed:16959810, PubMed:18182450).  Required for normal lung development and for normal patterning of trachael cartilage rings (By similarity).
What are the official names of this protein?
Protein Wnt-4.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: SMG_DROSE
Sequence: MKYATGTDNAMTSGISGQTNSSNSASNEMQPTTSTPTAVHKEATSTATTTATYANGNPNPSANPSQSQPSNALFCEQVTTVTNLFEKWNDCERTVVMYALLKRLRYPSLKFLQYSIDSNLTQNLGTSQTNLSSVVIDINANNPVYLQNLLNAYKTFQPCDLLDAMSSSSSDKDSMPCYGSDFQITTSAQCDERKLYARKEDILHEVLNMLPLLKPGNEEAKLIYLTLIPVAVKDTMQQIVPTELVQQIFSYLLIHPAITSEDRRSLNIWLRHLEDHIQAAAAGLTNRSYFLQPSPQLVAGGSSTGSGSCSSSATSSSTASCSSVASSSLCPASGSRSSRTNDWQTIAPPSKQLQNKLAGDWRGSGGGSSSGSINPLCDNLNGITLNELASSQNSLGLSLEGSSSLVNGVVAGAGSMLGIGGGDDHDTSFSKNGTEILDFDPVTANMGEACSLASSSLCGRNGGNPVEDRSQPPPNLQQQLLQPPPYASILMGNVGDQFGEINRWSLDSKIAALKTRRSNSLTTQTISSCSSSSNSSVITVNDNCSNSTENLAQFANKPRSFSLSIEHQRGALMNSGSDTRLDEFKPNYIKFHTRNVGMSGIGLWLKSLRLHKYIELFKNMTYEEMLLITEDFLQSVGVTKGASHKLALCIDKLKERGNILNRVEQELLTGQMELSTAVEELTNIVLTPMKPLESPGPPEENIGLRFLKVIDIVTNTLQQDPYAVQDDETLGVLMWILDRSIHNEAFMNHASQLKDLKFKLSKMKISMVPKMHHVKPAGVGPNNGNINKPRWNGKTRKCDSKSGSNDRINNRKNSNDMLNFSLNCLPHPLPHHSQQAPPPLPQFDYNGYGGGPSHQPQYKSSSYPSFMGNPQQQPPPPPSSKSHHHPQQMQQMLQQHNHFPALPQQTPPQSHRRSLNNLILVAGGPQQPQQLIFKPGQGVLTNNGSNDNLGLERNQQPQQQQQRKLSGGVSSAEQQPKKTMAAVVMENLAKFDQHFTLF
What is the function of this protein?
Translation regulator that binds to the 3'-UTR of specific mRNAs such as nanos (nos) and prevent their translation.  Prevents translation of unlocalized nos in the bulk cytoplasm via the recruitment of cup (By similarity).
What are the official names of this protein?
Protein Smaug.
What is the protein family that this protein belongs to?
Belongs to the SMAUG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_AERS4
Sequence: MEQARPIRRALLSVSDKTGILEFAKALNERGVALLSTGGTAKLLGDAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRDQDDAIMAQHNIYPIDMVVVNLYPFAATVAKAGCSLADAVENIDIGGPTMVRSAAKNHKDVAIVVKAADYARVIAEMDANGNSLKLATRFDLAIAAFEHTAAYDGMIANYFGTMVPSYGDNKEGDAESRFPRTFNSQFIKKQDMRYGENSHQAAAFYAEEHATPGSVSSAIQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDDLLTAYDRAYQTDPTSAFGGIIAFNRELDGATAAAIVARQFVEVIIAPSVSQEARDVVAAKQNVRLLECGQWTAPAQGFDLKRVNGGLLIQERDFGMVTQGDLKVVSKRQPTEAELKDLLFCWKVAKFVKSNAIVYAKEGQTIGVGAGQMSRVYSAKIAGIKAEDEGLTVAGSVMASDAFFPFRDGIDAAAAAGISCVIQPGGSMRDQEVIDAADEHGMTMVFTNMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: CEMA_MORIN
Sequence: MAKKKAFISLLYLASIVFLPWWISLSFTFNKSLESWVNNWWNTRPSEILLNDIQEKSILKKFIELEELSLFDEMLKEYSERRLQKLHVGVYNETIQWIKMHNEGRIHTILHFSTNIISFVILSVFSILSNEELIFLNSCLQEFLYNLSDTIKAFSILLLTDLCIGFHSPHGWELMIGSIYKDFGFAHNDQIISGVVSTFPVILDTIFKYWIFRYLNRVSPSLVVIYHSMND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: PPAC_EXISA
Sequence: MSTVLVFGHKNPDTDTITSALAYAELKKKLGMDAEAVRLGEVNGETQYALDHFRVKAPRLIESVKGEAEEVILVDHNEFQQSADGIEDVRILEVIDHHRIANFQTADPLYYRAEPVGCTATILLKLYKEHGVEIAADMAGLMLSAIISDSLLFKSPTCTDEDIKAAKELAEIAGVDAETYGLEMLKAGADLSQKTIEELISLDAKEFAMGDYRVEIAQVNTVDANDVLNRKAEVEAAIANTVAAKNLDLFVFAITNILTNDSEAIVVGPKPELFEQAFNVTLQNGLATLPGVVSRKKQIVPFLTEAATK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_NITEU
Sequence: MTSLVYAAKGIRILGIDPGLRITGFGIVEKIGNRLVYIGSGCVVTGESGLPDRLKTILDGLNEIILQHKPEQVAVEQVFVNINPKSTLLLGQARGAAISAAVLHELSVYEYTALQVKQAVVGNGHARKEQVQEMVMRLLGLGERPRPDAADALACAICHAHGGTGLLTLSARNRSKRSKRL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: SPO23_YEAST
Sequence: MLFSSSSSSLNSEVSQVFSENISSRSTTLTESSTQSEIRQHFGNEDFSGELPKKLIQLKKLKNGGTTIKKAKEDLEYCYDSLRLYENPYVTSSVDKKCGYSIELYLDNKYKTLMFSDLQLNADYPLYYDSSLDNISTNVERERATPLQIKGKIRINIDREDQALLITSHSISLKCFTKEYACFVNSETSKNSYSDKIIKELNHTEFFESSTYPKQQLRVIHHSLNDKKILLTKGTYDYPFTFTLQANTFPASFSSFFGKTHFRIESLTTIMRIPSKPKNLLKFLKNESFTDKIILTEEIKVKRVLPSTSMLKFETFQLRSYNTASEIVVSVIGNSKLIEIGMPFQMILSITKTDSSIELQEASLAVAQRMAIPSIDLKTKKILREPYIKKSEYLLRTVESQSFDSDKTIFGFCFDDVVIPTYADGLPSWFKTFYCEPSSFYPNHAALKVTHLLLFRITYSRNELVEGLEMKKNYRITVNFPILVGDSDISTSSLLPKYEKFENISDLQDEPPLYSMVAGENSL
What is the function of this protein?
Regulates expression of PIS1.
What are the official names of this protein?
Sporulation protein 23.
Protein: HISX_CAUVC
Sequence: MRRFLFSDPDFQTAFKAFLDERRGSPADVDAAVAGVLEAVRTQGIEALLDYSRRFDKVDLTAETIRVTAEEIEAGAAETPADVREAIAFAAARIRAYHSRQRPADQAWTDEAGVELGWRWTPLEAVGVYVPGGRAAYPSTVLMNAVPAQVAGVDRIAMVTPPGKLQPAVLAAAKEAGVTEIWRVGGAQAVAALAYGAGPIQPVDKIVGPGNAYVTAAKRRLYGVVGIDALAGPSEIVVVADNKNNPDWIAADLLSQAEHDPAAQSILITDDEAFAAAVEQAIAERLKTLATGEDAAASWRDHGAVIIAPLDESPALVDAIAPEHVEFALDNPERLSDRVRHAGAIFLGRVTPEAIGDYVAGSNHVLPTSRAARFQSGLSIYDFIKRTSIVKCDPASFAVLGPHTVALAKAEGLPAHALSASVRLPSGD
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: LSPA_BIFAA
Sequence: MKNDQRRLRDRVAVFACIAIAAIAIDQLTKMWALSALADGRTIRVIPGLLSLTLVRNPGASLGMGSGMTWLISLLAMAACVALVVLAVRTISMKWTVLFAFAFAGAFGNLIDRVIYAEGFLNGKVVDFLNYGWSIGNVADIFLMLAGVAAVLLLFLGEPFSQKDLDEANGKTLGDDANATDDGAKAA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU2C2_SOYBN
Sequence: MIWHVQNENFILDSTRIFMKAFHLPLFDGSFIFPECILIFGLILLLMIDSTSDQKDISWFYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFILTATLGGMFLCGANDLITIFVALECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGILIALLFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVSFGLRTGTDNIRDYAGLYTKDPYLALSLALCLLSLGGLPPLSGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRPPLRSNNSIELSMIVCVIASTIPGISMNPIIEIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HOG1_BEABA
Sequence: MAEFVRAQIFGTTFEITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENVISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMLDGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVKSLPKRERQPLRNKFRNADDSAIDLMERMLVFDPKKRITAAEALSHDYLAPYHDPTDEPVAEEKFDWSFNDADLPVDTWKIMMYSEILDYHNVEAGASGLEDGSVPAQ
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase HOG1, MAP kinase HOG1, Bbhog1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KCS20_ARATH
Sequence: MSHNQNQPHRPVPVHVTNAEPNPNPNNLPNFLLSVRLKYVKLGYHYLISNALYILLLPLLAATIANLSSFTINDLSLLYNTLRFHFLSATLATALLISLSTAYFTTRPRRVFLLDFSCYKPDPSLICTRETFMDRSQRVGIFTEDNLAFQQKILERSGLGQKTYFPEALLRVPPNPCMEEARKEAETVMFGAIDAVLEKTGVKPKDIGILVVNCSLFNPTPSLSAMIVNKYKLRGNILSYNLGGMGCSAGLISIDLAKQMLQVQPNSYALVVSTENITLNWYLGNDRSMLLSNCIFRMGGAAVLLSNRSSDRSRSKYQLIHTVRTHKGADDNAFGCVYQREDNNAEETGKIGVSLSKNLMAIAGEALKTNITTLGPLVLPMSEQLLFFATLVARKVFKVKKIKPYIPDFKLAFEHFCIHAGGRAVLDEIEKNLDLSEWHMEPSRMTLNRFGNTSSSSLWYELAYSEAKGRIKRGDRTWQIAFGSGFKCNSAVWKALRTIDPMDEKTNPWIDEIDDFPVQVPRITPITSS
What is the function of this protein?
Mediates the synthesis of VLCFAs from 22 to 26 carbons in length (e. g.  C22, C24, C26) (PubMed:15277688).  Functionally redundant with KCS2 in the two-carbon elongation of C22 fatty acids that is required for cuticular wax and root suberin biosynthesis (PubMed:19619160).
What are the official names of this protein?
3-ketoacyl-CoA synthase 20, KCS-20, Very long-chain fatty acid condensing enzyme 20, VLCFA condensing enzyme 20.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: GREA_DESVM
Sequence: MSSIPISTEGYDRLMKELERLKSERPAIIQAIKEAREEGDLKENAGYDAARERQGMLEARISYIESRMAQFNVINLDSLSGDKVMFGATVEIEDLDSGEAKRYTLLGPDEADYAQGTISVLSPVARALLGKEEGDEIVVDAPRGRISYEIISVAFEGARR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RLMH_THET8
Sequence: MRLRVVAVGRPRLAYARLGVEEYARRMRRYAPLDLVFVRKGEELLPKAEGHRKVVLDERGRLLTTEELYRRLLAWEGERVAFLVGGAEGHPEAVREEADLLLSLSPLTLQHELALLVLMEQLYRVLTLRAGHPYHRP
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNRD_STRTR
Sequence: MKVDDDLVRQVIRPRLRGSHKGSYGRVLLVGGLYPYGGAIIMAAIACVNSGAGLVTVATDRENIIALHAHLPEAMAFDLRETERFLDKLRAADVILIGSGLGEEETADWALELVLANIRSNQNLVVDGSALNLLAKKNQSSLPKCHLILTPHQKEWERLSGLAISEQSVSNTQRALEEFQSGTILVAKSHKTAVYQGAEVTHLEVGGPYQATGGMGDTLAGMVAGFLAQFASTDSYKAVIVATWLHSAIADNIAENAYVVLPTRISKAIPSWMKKLSL
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ADP-dependent (S)-NAD(P)H-hydrate dehydratase, ADP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
Protein: RL34_SHEB5
Sequence: MSKRTFQPSNLKRKRSHGFRARMATVGGRKVLARRRAKGRARLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DAAF1_PERPL
Sequence: MHPEVSEQQADGATEPSLEESAGDHSGAGPGVRKEEINETKETCVGPSTTSCQSQKQQSGDSRLDCRSGYARNDRDDRGPRMTKEFLQKLCKQHKLYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLECNGIQRIENLQAQSELRCLFLQVNLLHKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNRLETVADIQHLRECLRLCVLDLSHNMLSDPEILSVLESMPCLRVLNLMGNPVTKHIPNYRRTVTVRLKQLTYLDDRPVFPKDRACAEAWARGGYAAEKEERLQWESREHKKITDSLEALAMIKRRAEERKKARDKGETPLPDSEESSSTSPEAQDKPPLGETQQKIEVLVEESFKAKDELFPEKPGGEEELAVVADRTMEEPDLPGSLAQSQTPLVATAEESTSSVAATDGTGIEDTEAIALENKERLFIDDLPDLEDVDGMDISMEDQTKETGIPKIQVISSLSDDSDPELNDSPLPMLEHTPTGSTGVLSNIFAVCKDSSKAARVPLTDIYEPRATTAPETQGQVFSTTPPRPLIQELEEDGRGENESKQSLPAQSSEDGDSQLPEATLLGDRAENEAQSSLDLGKPSPRASLEDIEFGLD
What is the function of this protein?
Cilium-specific protein required for the stability of the ciliary architecture.  Plays a role in cytoplasmic preassembly of dynein arms (By similarity).  Involved in regulation of microtubule-based cilia and actin-based brush border microvilli (By similarity).
What are the official names of this protein?
Dynein axonemal assembly factor 1, Leucine-rich repeat-containing protein 50.
What is the protein family that this protein belongs to?
Belongs to the DNAAF1 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: Y426_ARCFU
Sequence: MFFEFKKHFWKNPVLSLEISRILCNASSYVLPQGILKVEEGAFDAINRKFDDFMEGKAEVDELMAEADRLEEKLNEQLNRNFGYLHELGLEPHAKVAFVSRILSRGFVYPDVQIFVGKRACKKLRELSKVERRILEGRIELGKGREKLLRLEGKLLGYPDCCVGSYIESKRGFPAESRFIMECAEKGVFVKSLKALKSSKLISIPYLFTSNFYPCSIECSKAVKVGLKIQEWLDEFEDAFKLRSMLIALFYAATALRASKAAGNYGEKLRSFFSSLSPGDIGLIETLERHSGNQAEFTNLFIARILGGFSKG
What are the official names of this protein?
Uncharacterized protein AF_0426.
Protein: RL22_HALHL
Sequence: METQAKLRFSRVSPQKARLVADQIRGLPVDDALRTLEYSPRKAAEIVRKVLESAVANAEHNDGADVDELRVARIFVDEGPTMKRIQPRAKGRANRILKRTSHITVAVAED
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: METK_THESQ
Sequence: MRRLFTSESVTEGHPDKIADQISDAILDAMLEQDPRSRVAVETLVTTGLVIIAGEVTTRAYVEIPDIARKTILEIGYTRAKYGFDGETCGVLTSIHSQSPDIALGVDKALEVKTGEEVADEFEALGAGDQGIMFGYATNETPEYMPLPITLAHKLAMRLAEVRKNGTLPFLRPDGKTQVTIEYEDDKPVRVDTVLISTQHDPDISQADLREAIIEHVINPVIPEQYRDDKMKILVNPTGRFVLGGPMADTGLTGRKIIVDTYGGWVPHGGGAFSGKDPTKVDRSAHYMARYVAKNVVAAGLADKFLIQLSYAIGVAKPVSIMIDTYGTAKVDEDKLLKVITELFDFRPGAIIKKLNLLRPIYRKTAAYGHFGRNEEEFTWEKLDMVDELKRAFNM
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_METC4
Sequence: MAREGKRIRAAREGLEPMKLYAIDEAIKLVKSKASAKFDETVEISMNLGVDPRHADQMVRGVCNLPNGSGRTVRVAVFARGAKADDARAAGADIVGAEDLLEIVQGGKIEFDRCIATPDLMPLVGRLGKVLGPRGLMPNPKVGTVTMDVKGAVAAAKGGAVEFRVEKAGIIHAGVGKVSFDEQKLVENIKAFADAVAKAKPTGAKGTYIQRIAVTSTMGPGVKVEPSTVLTA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ACKA_HELAH
Sequence: MEILVLNLGSSSIKFKLFDMKENKPLASGLIERIGEEVGQLKIQSHLHHDKQEVKKQLFIKDHASGLLMVREHLTKMGIIKDFDKIDAIGHRVVQGGDKFHAPVLVDEKVMQEIERLSILAPLHNPVNLAGIKFVKTAHPHIPQIAVFDTAFHATMPDFAYMYALPYELYEKYQIRRYGFHGTSHHYVAKEAAKYLHIPYHKFNAITLHLGNGASVAAIKDGKSVDTSMGLTPLEGLIMGTRCGDIDPTVVEYIAQCANKSLEEVMKILNYESGLKGICGDNDARNIETRAKKGDKQAKLAFEMCAYRIKKHIGAYMVALGRVDAIIFTGGMGENYPALRESVCEGLEKLGIALHKPTNDNPGSGIVDLSQPNTKIQVLRIPTDEELEIALQTKRVLEKH
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_MAGMM
Sequence: MAERLRIAVDGPAGAGKGTVCRAVARRYQWAYLDTGAIYRAVALHALNSENFEETSLAQWAAQMDFRFEVDAQGDAHAFLEGTEVTNKLRDEQVGETASQVAAMPAVRTALLDFQRNYGSPQSVILDGRDVGTVVLPDADLKIYLTASLQARAQRRTLELQGKGESVSMDRIKSRIEERDARDQSRATAPLAAAPDAQTVDTTYLSQTESIETVARLVASLLEKP
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.