PharMolix/UniProtQA huggingface dataset:
Protein: LEUD_NEIMF
Sequence: MKAFTKITAIVAPLDRSNVDTDAIIPKQFLKSIKRSGFGPNAFDEWRYLDHGEPGMDNSKRPLNPDFSLNQPRYQGAQILLTRKNFGCGSSREHAPWALDDYGFRAVIAPSFADIFFNNCYKNGLLPIVLTEEQVDRLFKEVEANEGYQLSIDLAEQTLTTPGGETFTFDITEHRKHCLLNGLDEIGLTLQHADEIHAFEEKRRQSQPWLFNG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: TSAD_RHIE6
Sequence: MVPFPRILGIETSCDETAAAVVERDAEGHSRILSDVVLSQLDEHSAYGGVVPEIAARAHVEALDELIEEALMRANVSLADVDAIAATSGPGLIGGLLVGLMTGKAIAKAAGKPLYAVNHLEGHALTARLTDGLSFPYLMLLVSGGHTQLILVRGVGDYERWGTTIDDALGEAFDKTAKLLGLPYPGGPAVERMARDGNAGRFDFPRPLVGEARLDFSFSGLKTAVRLAAQEIAPLSDQDVADICASFQRAISRTLKDRIGRGLQRFKREFPSIGETPALVVAGGVAANLELRATLQGLCDKNGFRFIAPPLSLCTDNAVMIAWAGLERMAIGVAPDALDVQPRSRWPLDANAERLIGFGKRGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_AZOSB
Sequence: MAKGKFERTKPHVNVGTIGHVDHGKTTLTAAITTILSKKFGGEAKAYDQIDAAPEEKARGITINTAHVEYETATRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSKYDFPGDDIPIVKGSALKALEGDQSDIGEPAIFRLADALDSYIPTPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIVKVGEEIEIVGIKPTVKTTCTGVEMFRKLLDQGQAGDNVGVLLRGTKREDVERGQVLCKPGSITPHTHFTGEIYVLSKEEGGRHTPFFNNYRPQFYFRTTDVTGSISLPEGTEMVMPGDNVSITVKLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_METMA
Sequence: MFEGAMPALITPFTKDDRIDREGLQRNIAFVEEGGVSGIVPCGTTGESATLSAAEHEEVIDIAVECSKVPVIAGTGSNNTGEALQFTKHAADAGVDGVLLISPYYNKPNPAGLLAHFKKIAEAVDIPMILYNVPSRTGQDMPVDVIVELAKVENIVGIKEASGNAAKVSQILENTMDDDFVVLSGEDGLTLPIISMGGRGVISVAANIVPDKMSGMVNAALKGDYETARKLHFEIAPLIRALFLETNPIPVKKAAELVGLASGHLRLPLAPISDANQAKLANELRKLGVME
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIA1_MOUSE
Sequence: MNSVGEACTDMKREYDQCFNRWFAEKFLKGDGSGDPCTDLFKRYQQCVQKAIKEKEIPIEGLEFMGHGKEKPENSS
What is the function of this protein?
Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes.  In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane.  Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo).  Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.
What are the official names of this protein?
TP53-regulated inhibitor of apoptosis 1, Protein 15E1.1, WF-1, p53-inducible cell-survival factor, p53CSV.
What is the protein family that this protein belongs to?
Belongs to the TRIAP1/MDM35 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion intermembrane space.
Protein: GCD1_ARATH
Sequence: MYNLSRIIYRFSSVSLNPSTRASGFLLENASSKILQSATNRAFSAKSGSDGVGGDDNGWNISTGGSFGGTGSADLDWDNKSMWSTGLTKEHFDGVSVGRQKNAANPSSDNTPSDSGDVMSKLGPKEVALVNEMNEYDDLLKEIEQDNRQGRAFVDGIKQRMMEISVLLKQVKEPGARGSYLKDSEKTEMYRLHKENPEVYTIERLAKDYRIMRQRVHAILFLKEDEEEEERKLGRPLDDSVDRLLDEYPEFFISHDREFHVASLNYKPDFKVMPEGWDGTIKDMDEVHYEISKKEDDMLYEEFVRRFEFNKMKWRGEVMCHKYSRRRSSEGWKITVEKLGAKGKRGAGGGWKFMSLPDGSSRPLNEMEKVYVKRETPLRRRSIISTEVMRYSPANQKRRSKRKQKRKERRIACLKAGKQT
What is the function of this protein?
Essential for fertility (male and female gametophyte functions and development) (PubMed:23085019).  Required for the integrity of female gametic mitochondria (PubMed:23085019).  Modulates male gametophyte functions, including pollen tube growth and style penetration (PubMed:23085019).  Involved in mitochondrial-driven cell-to-cell communication in embryo sacs during female gametes maturation (including embryogenesis initiation and endosperm development), especially for reciprocal signaling between central and egg cells which regulates reciprocal development (PubMed:23085019).
What are the official names of this protein?
Protein GAMETE CELL DEFECTIVE 1, mitochondrial, AtGCD1.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GRPE_THEAC
Sequence: MQPTPSEYARTPVRIEMQRSKERNSMVYKEMYNDAQRKYSEALDRISKLTDAYLREKAEVENFIKIKDREVEMSKKNANEKLLKDFLPVLDSIDAAIQAEKDNNLIRIRDQMLGVLSRYGLKPIKAEGSKFDPYLHEVVGVTADGEDGMVKYEVQRGYTLNDGVLRTSKVIVVKR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_HAEIE
Sequence: MAVQQNKKSRSRRDMRRSHDALTTAAVSVDKASGETHLRHHVTADGYYRGRKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MZT1_SCLS1
Sequence: MADTSQKPDKATSAAQARQVIDVFHEISTLLNAELDRGTLSICISLIENGVNPEALATVVRELRKDADEVRRQIAQGVVQDGE
What is the function of this protein?
Required for gamma-tubulin complex recruitment to the microtubule organizing center (MTOC).
What are the official names of this protein?
Mitotic-spindle organizing protein 1, Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1.
What is the protein family that this protein belongs to?
Belongs to the MOZART1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: MAF1_ASHGO
Sequence: MKFIDELDLELVNQTLNFETSESKISGGCDIFTTKPVASDKKLYKTIDRHLESLLQENESYNAAIQQQIELENKRRDPKQAGSDCAEPAEDSPTRNANSFWEQKRRMSVSESPRADTSPLFKSQKLNDQQLKELVSHPLEVPGCKSPSNETSARGVLRRSTSAGSFENNAGSAEQQKRRTSSIGSAANGTKSPILRRSSFNRETINIGPFGPISETASRRTFAYLIGILNASYPDHDFASLKPTDFVKSSRKQLVSKFENSIIALGKQPQEWIWETINAHMDLADCVFYQYNPQESFLDDEPGHLWSLMWFMFNKKRKRVAYFYLSAFRVKNPPSTGGSVALDEYYDSNSKPELREKRRRLTIEHETNDFEGEYDLTYTSSGDGAVEDEDEDMNDAD
What is the function of this protein?
Mediator of diverse signals that repress RNA polymerase III transcription.  Inhibits the de novo assembly of TFIIIB onto DNA (By similarity).
What are the official names of this protein?
Repressor of RNA polymerase III transcription MAF1.
What is the protein family that this protein belongs to?
Belongs to the MAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL20_VIBVU
Sequence: MPRVKRGVQARARHKKVLKQAKGYYGARSRVYRVAFQAVTKAGQYAYRDRRAKKRQFRQLWIARINAASRQNGLSYSRFINGLKKASIEIDRKILADIAVFDKAAFAVLVEKAKAAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MNMG_ECOSM
Sequence: MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDLAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREASGEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASB_HUMAN
Sequence: MKVLILACLVALALARETIESLSSSEESITEYKQKVEKVKHEDQQQGEDEHQDKIYPSFQPQPLIYPFVEPIPYGFLPQNILPLAQPAVVLPVPQPEIMEVPKAKDTVYTKGRVMPVLKSPTIPFFDPQIPKLTDLENLHLPLPLLQPLMQQVPQPIPQTLALPPQPLWSVPQPKVLPIPQQVVPYPQRAVPVQALLLNQELLLNPTHQIYPVTQPLAPVHNPISV
What is the function of this protein?
Important role in determination of the surface properties of the casein micelles.
What are the official names of this protein?
Beta-casein.
What is the protein family that this protein belongs to?
Belongs to the beta-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: SMN_BOVIN
Sequence: MGGGGGGFPEPEDSVLFRRGTGESDDSDVWDDTALIKAYDKAVASFKHALKNGDISEASEKPKGTPKRKSAKNKSQRKNTTSPSKQWKVGDNCCAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPTSEVANIEQNAQENENESQISTDESENSSRSPLNKPNNIRSRAAPWNSFLPPPPHMPRSGLGPGKSGLNFSGPPPPPPPPPHFLSRWLPPFPAGPPMIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFKQSQKEGRYSHFN
What is the function of this protein?
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP.  To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate.  Binding of snRNA inside 5Sm ultimately triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP.  Within the SMN complex, SMN1 acts as a structural backbone and together with GEMIN2 it gathers the Sm complex subunits.  Ensures the correct splicing of U12 intron-containing genes that may be important for normal motor and proprioceptive neurons development.  Also required for resolving RNA-DNA hybrids created by RNA polymerase II, that form R-loop in transcription terminal regions, an important step in proper transcription termination.  May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).
What are the official names of this protein?
Survival motor neuron protein.
What is the protein family that this protein belongs to?
Belongs to the SMN family.
What are the subcellular locations of this protein?
Nucleus, gem. Nucleus, Cajal body. Cytoplasm. Cytoplasmic granule. Perikaryon. Cell projection, neuron projection. Cell projection, axon. Cytoplasm, myofibril, sarcomere, Z line. Note=Colocalizes with actin and at the Z-line of skeletal muscle (By similarity). Under stress conditions colocalizes with RPP20/POP7 in punctuated cytoplasmic granules. Colocalized and redistributed with ZPR1 from the cytoplasm to nuclear gems (Gemini of coiled bodies) and Cajal bodies. Colocalizes with FMR1 in cytoplasmic granules in the soma and neurite cell processes (By similarity).
Protein: DHE4_SCHOC
Sequence: MIKNGLPHEPEFQQAYNELVSALEESTLFTEKPEYKKVIPVVSIPERIIQFRVAWENDNGDVEVNNGFRVQFNSSLGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLSMGGGKGGCDFNPKGRSDGEIRRFCVAFMRQLARYIGADTDVPAGDIGVGGREIGYLFGAYKQMQNNWYGVLTGKGLTWGGSLIRPEATGYVSFTTLKKMIEKATNGKESFKGKRVELSGSGNVAQYAALKVIELGGIVVSLSDSKGSIVSKNGIVPEQVLEIAAAKLKFKSLEEITKESVKLFSGENSVEYLAGVRPWAKVGHFDVALPSATQKEVSGEEEAKALVEAGCKYIAEGSNMGSTKEAIDVFEANRSNNVWYAPGKAANCGGVAVSGLEMAQNSQRVQWSAEEVDAKLKNIMYTCFDNCYDPAIKYSAEKNADGLPSLLKGANIASFIKVADAMFDQGDVY
What are the official names of this protein?
NADP-specific glutamate dehydrogenase, NADP-GDH, NADP-dependent glutamate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: RL3_SULIA
Sequence: MGHRKLASPRRGSAGLRPRKRSSELLPTPRTWPQINSPNPKLLGFVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEVPPIIPLALRAYAVDGKGEPNVITEYWSPSSLQFLDITRRIRSFSSFLKNDESKKKFEEKFGSKLDLIKSNLDRIVYFRLLVATQPRKIPSLGKKVPDLVEIQIGGGEKKAQLDYALNVLGKEISIKDVFKEGQLIDVVGVTKGKGFAGVIKRYSVVELPRWHKHRKGSRKIGTRGPSLGTPSYTPQPGQLGFHRRTEYNKRIIKIGDDPKEINPAGGFVRYGIVRNTYILLEGSILGSKKRPIFLREAVRPSYVFENAPKITYVNLLSKQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HSCA_VARPS
Sequence: MALLQISEPGQAPDPHQRRIAVGIDLGTTHSLVAAVRNGVAECLPDDQGRVILPSAVRYLDRERRQIGFDALAARAQDAANTITSVKRLMGRGLADIANRESMSYRLVDEGGMVKVETAAGIKSPVEISAEILATLRYRAEDTFDGELYGAVITVPAYFDEGQRQATKDAAQLAGLNVLRLISEPTAAAIAYGLDNASEGVYAVYDLGGGTFDISILRLTQGVFEVIATGGDSALGGDDYDHALADFVLAQTGLQVGSDADKAAVLVAARAAKEALTDADSVAFHAKLAGGAARFDLARAQFDAATKPLTDRTIAAVRKALRDAKLKPDDLQGIVLVGGSTRMPQIRRAVAEFFGREPLVNLNPDEVVALGAAIQANQLAGNNGAGDLLLLDVIPLSLGIETMGGLVERIVPRNQTIPTAMAQDFTTYQDGQTALALHVVQGERDLVADCRSLARFTLRGIPPMAAGAARIRVTFTVDADGLLSVSAKEQGSGVEASVAVKPSYGLSDDQIATMLQESFSTAQQDMQARALVEARVDAERMLLATQSALDADGDLLGEEERAVIDASMAKLREAAKGNDAAAIEGATKALANDTEAFAAQRMNAGIARALSGRKLESL
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RGLB_ASPFC
Sequence: MRFAIPLGAACAWAGVALAALQIAEDFSSITLNNDRFKAVWSKSKGSVVDMFLDGQDLLGPQSGSTGIGPYLDCYCVPSGFYTAGATNPRMQYVEGTDSTGTKYAGVILNDTYTPTGQQFQQYWFLRDGETGLHMFSRLAYYNETTPFLRNLQEFRTLFRPNTQLWTHLTSSELQTAPLPSKNAVSKQVVVQDATWRFNNTPDDAYYTQFSEYFTKYTFSNQWRDNDVHGLYGDGTNSNGSTYGAWLVMNTKGPLHSDLTVDGIVYNYIVSNHHGEGTPNITNGFDRTFGPQFYLFNGGKGSTSSLQDLRSEAAKLADPSWNAEFYDSIAKHVVGYVPSSKRGSVDGRIKLPKGASNPIAILTVDGQYFQDNSVVPSSYQYWTDIDTSGRFRIDRVVEGKYRLTVYADGIFGDFVRDGVTVRAGKTTTVKEKWDAESAGKEIWRLGTPDKSSGEFRHGVARDPTHPLHPPEYLIYWGAYDWQSDFPKGIDYTIGSSDPATDFNTVHWSVFGPTPDNPNVEYNTTHDWKINFSLTKKQLRNSKKATLTIQLAGAKTASGNTDEYKASEPYINLIHESYINDQKEPLSFVIGFNQSSSCIVRSAVSCYQVRSRMEFPADWLKVGENTLTLHLPYNATDTETAILPATVYVQYDALRLELD
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity).
What are the official names of this protein?
Probable rhamnogalacturonate lyase B.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR5_RHIEC
Sequence: MSQSGKNGLTYSDAGVDIDNGNLLVEKIKPAVRSTRRPGADGEIGGFGGLFDLKAAGFTDPVLVAANDGVGTKLKIAIDADYHDTVGIDLVAMCVNDLVVQGAEPLFFLDYFATGKLVPDQGAAIVGGIAAGCREAGCALIGGETAEMPGMYSSGDYDLAGFAVGAAERGKLLPSGDIAEGDVILGLASSGVHSNGFSLVRKIVELSGLGWDAPAPFAEGKKLGEALLEPTRIYVKPLLKAIRETGALKALAHITGGGFPENIPRVLPEHLAAEIDLGAVKVPPVFSWLARTGGVEAKEMLRTFNCGIGMIVVVAEENVAAVSKALEAEGEKVVTLGRMIARAEGAAGTVYKGTLAI
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRA_HAES1
Sequence: MITIKKGLDLPIAGKPEQVIHNGNAVKEVALLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGIVFTAPASGTVTAINRGAKRVLQSVVIKVEGNEQITFTQYNEDELKKLTSDQVRQNLQSSGLWTALRTRPFSKVPASDAVPSSIFVNAMDTNPLSANPEIVLKEHWQDFTDGLTVLSRLHEGKLHLCKAGDSNIPTIDLPNLAVHDFSGPHPAGLSGTHIHFIDPVSVTKSVWYLNYQDVIAIGKLFTTGEIYTDRVVSLAGPQVKNPRLIRTQLGANLSHLTENELSAGENRVISGSVLSGNTAIGPYNYLGRYALQVSVIAEGREKEFLGWIMPGKNKFSITRTVLGHFSSKLFNFTSAVNGGHRAMVPIGAYERVVPLDIIPTLLLRDLASGDTDSAQALGCLELDEEDLALCTFVCPGKNEYGPMLRAALDKIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: PLH32_FORAG
Sequence: MLFLRFKFFNNRLLFVSVLCFVICVSCKREHKEIKIKGEKATELKLPERPNILWLVTEDMGAYIPPFGDSTVVTPHLSKLAKEGVIYPNLYSTSGVCAPSRAAIATGMYPSSIGANHMRTNSFTKERGLPAYEAVPPSNVRMLSEWLRKAGYYCTNNYKTDYQFKAPVTAWDESSPYAHWRNRNDDQPFFAVFNFTDTHESGLFEPYGLREIETRLYRAGDTTYQWKNYGASHANNRMSEAETPQYLSKDTKFNIPPYLPETDLVKRDMWKLYNNIGEMDNQVGAVLQQLEDDGLLENTIIFFYGDHGGPLPREKRLIYDSGLNTPMIIRFPNKLEAETSDPQLISFVDFAPTLLSIIGEKPKEYMQGQAFLGQYKNKERSYIHAAADRFDAETDVIRAVRDKRFKYIRNYRPEQGYYLPIDYRERIPTMQELLRLKAEGKLNEEQMQWFRDVKPEEELFDCKSDPFELKNLANNPEYQNKLVELRKELDRWLTAIGDDANLPESELINKLWNGSNTQPVTSDPKVSINNGNITISCDTEGASVGYKIVTAGNKTSKTWHIYNGPFKMPLGSTLEIIAHRIGFKPSKAIQISTSDL
What is the function of this protein?
Sulfatase involved in ulvan degradation (PubMed:31285597).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).  The sulfatase desulfates Xyl2S-Rha3S, product of the degradation of ulvan by endo-acting alpha-1,4-L-rhamnosidase, to Xyl-Rha3S (PubMed:31285597).
What are the official names of this protein?
Ulvan-active sulfatase, Polysaccharide utilization locus H protein P32, PUL H protein P32, Sulfatase family S1 subfamily 8 protein P32, P32_S1_8.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MAN1_YEAST
Sequence: MSSEDIIYDPQFKPVQGIYENRLRQFIDTGGDYHDLNLPKFYDKKRISLDHDHVKVWWYQVSFERGSSPVSPDKRPSWKSIIERDKKGELEFREANINQPFGPSWSTTWFKVKISLPEDWVKSNEQLLFQWDCSNEGIVIDPKTLIPVTAFSGGERTEYVLPKTSDGKHFFYIEAGNNGMFGCGAGSTINPPDDNRFFHLRKADIVWPDLDARALYIDFWMLGDAARELPGDSWQKHQARQLGNAVMNLFDPNDRSSVRKCRELLQREYFDSFLESSKVYEQGESQVLTNVYGIGNCHIDTAWLWPFAETRRKIVRSWSSQCTLMDRFPEYKFVASQAQQFKWLLEDHPEFFNKVLIPKIQQSQFFAVGGTWVENDTNIPSGESLARQFFFGQRFFLKHFGLKSKIFWLPDTFGYSSQMPQLCRLSGIDKFLTQKLSWNNINSFPHSTFNWAGIDGSQLLTHMPPGNTYTADSHFGDVLRTAKQNKTPEYYGSGLMLYGKGDGGGGPTEEMLQKMRRIRSMNNRNGNVIPKLQVGITVDEFYDDILKRTNQGHDLPTWSGELYFEFHRGTYTSQAQTKKLMRLSEIKLHDLEWIAAKTSVLYPDSYKYPSKQINELWENVLLCQFHDVLPGSCIEMVYKYEAVPMLHNVVKECTSLIDKTVQFLQSQSKADLVEMRTLTWSKPEKVSEECSLNGSYTSSVTGYDDYIVLANGKLKVIICKKTGVITSITDETLGVEYLDTEHGRNKLGANQFVIYDDKPLGWQAWDTELYSVNQYKYVTKPKKVQVSCNTKEKCAVEVIFQISEKCKIKSVISLNATAVTDAKLSKVDISTTVENWDARNKFLKVEFPVNIRNDFASYETQFGITKRPTHYNTSWDVAKFEVCHHKFADYSEYSKGVSILNDCKYGFSTHGNLMRLSLLRSPKAPDAHADMGTHEIKYAIYPHRGALSSDTVKLAHEFNYCFKYKLPKDIGMNFDDIISISGDENVILSNIKRGEDDSAVKSNYSLNPRDEQSIVVRVYESLGGESFASLNTTLNLKRIEKVDNLEMKVYKSLTATRDESNHAINRIPIKLRPFEIASFRLYF
What is the function of this protein?
Degrades free oligosaccharides in the vacuole.
What are the official names of this protein?
Alpha-mannosidase, Alpha-D-mannoside mannohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 38 family.
What are the subcellular locations of this protein?
Vacuole. Note=Localizes to the inner surface of the vacuolar membrane. Under nutrient-rich conditions, the protein is delivered to the vacuole by the cytoplasm to vacuole targeting (Cvt) pathway. Under starvation conditions, the protein is localized through autophagy.
Protein: MGSA_ECO81
Sequence: MELTTRTLPSRKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: GFOD1_XENTR
Sequence: MLPGVGVFGTSLTSRVIIPLLKDEGFSVKALWGRTQEEAEELAKEMSVPFYTNRIDDVLLHQDVDLVCINLPPPLTKQIAVKTLGIGKNVICDRTATPLDAFRMMSAAHYYPKLMSIMGNVLRFLPAFVKMKQLIQEGYVGELQVCEVQVHSGSLLGKKYNWSCDDLMGGGGLHSVGSYIIDLLTFLTSQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFNVPGEFKQDVIVVGSAGRLIVTGIDLYGQRNSSSDRELLLKDSTPVSNSLLPEKAFSDIPSPYLRGTIKMVQAVRQAFQDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKKSNQTGEWQNIVIMTEEPELSPAYLISEAMRRSRMSLYC
What are the official names of this protein?
Glucose-fructose oxidoreductase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPH_BACCR
Sequence: MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPETVQAFVNKKSGVLFGEWSEIKTILDENNKHIVDYVVENDRRNSAIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSAKPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTKAKTEIKQELRQLNPEK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.