PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_RHIME
Sequence: MAKVIGIDLGTTNSCVSVMDGKDAKVIENAEGARTTPSMVAFTEDGERLVGQPAKRQAVTNPENTLFAIKRLIGRTFEDPTTQKDKGMVPYKIVKADNGDAWVEAHGTSYSPSQISAMILQKMKETAESYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLDVLRIINEPTAAALAYGLDKKEGKTIAVYDLGGGTFDISVLEIGDGVFEVKSTNGDTFLGGEDFDMRLVEYLASEFKKEQGIDLKNDKLALQRLKEAAEKAKIELSSSQQTEINLPFITADASGPKHLTMKLSRAKFESLVEDLIQKTIAPCKAALKDAGVSAAEIDEVVLVGGMTRMPKVQETVKQLFGKEPHKGVNPDEVVAMGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIERNTTIPTKKSQVFSTADDNQSAVTIRVSQGEREMAADNKLLGQFDLVGIPPAPRGVPQIEVTFDIDANGIVQVSAKDKGTGKEHQIRIQASGGLSDAEIEKMVKDAEANAEADKKRREGVEAKNQAESLVHSSEKSLQEHGDKVSETDRKAIEDAIAALKSAVEVSEPDAEDIKAKTNTLMEVSMKLGQAIYEAQQTDAAHADAAADAKRSGDDVVDADYEEVKDEDDRKRSA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: V29K_TRVPS
Sequence: MEDKSLVTLKKKTFEVSKFSNLGAIELFVDGRRKRPKYFHRRRETVLNHVGGKKSEHKLDVFDQRDYKMIKSYAFLKIVGVQLVVTSHLPADTPGFIQIDLLDSRLTEKRKKGKTIQRFKARACDNCSVAQYKVEYSISTQENVLDVWKVGCISEGVPVCDGTYPFSIEVSLIWVATDSTRRLNVEELNSSDYIEGDFTDQEVFGEFMSLKQVEMKTIEAKYDGPYRPATTRPKSLLSSEDVKRASNKKNSS
What are the official names of this protein?
29 kDa protein.
Protein: YWJB_BACSU
Sequence: MERKTVLYIAVSLDGMIAKEDGSIDWLDEFEGEGDNGYSDFYQTVDTVILGRSTYEHVKVLTPVFPYQDKTCYVFTGSPDSYQDEHVTFINEGARAFTARLKQEKGSNIWIAGGAELVNDFMKEDAIDEFIITVIPVVLGSGIPLFHELTNETKLRLKGTKQFGQAVQLHYVRA
What are the official names of this protein?
Uncharacterized protein YwjB.
What is the protein family that this protein belongs to?
To B.subtilis YyaP.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YL464_YEAST
Sequence: MQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDILHIILRACALNFGAGPRGGAGDEEDRSITNEEPIIPSVDEHGLKVCKLRSPNTPRRLRKTLDAVKALLVSSCACTARDLDIFDDNNGVAMWKWIKILYHEVAQETTLKDSYRITLVPSSDGISDTLTVIQSFSYSLLPVLSATYTSMIQQDASNCTLITTRTVHRSLD
What are the official names of this protein?
Putative uncharacterized protein YLR464W.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily.
Protein: KCY_STRT1
Sequence: MKDIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYLALQNGLTEENVPEILDQLSQNPISFGKAADGSPKVYVGDVDITHPIRDNQVTNNVSWVAAIPEVRQELVSQQQRIAQEGGIIMDGRDIGTVVLPDAELKIFMIASVDERAERRYKENIEKGIPADLETLKKEIAERDYKDSHREVSPLRPAEDAITFDTTGVSIDGVVEFIQEKAKKIIDKG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_SALPA
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQVAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLEGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFNMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLEDLADLDVLSTDDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_THEFY
Sequence: MAKPPVRKPKKKVCVFCQEKMTYVDYKDTTLLRKFISDRGKIRARRVTGNCTQHQRDVAKAVKNAREMALLPYTSSAR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PAFA_BOVIN
Sequence: MLPSKLHALFCLCTCLALVYPFDWQDLNPVAYIESPAWVSKIQALMAAANIGQSKIPRGNGSYSVGCTDLMFDYTNKGTFLRLYYPSQDDDHSDTLWIPNKEYFLGLSKFLGTHWLVGKIMGLFFGSMTTPAAWNAHLRTGEKYPLIIFSHGLGAFRTIYSAIGIDLASHGFIVAAVEHRDGSASSTYYFKDQSAVEIGNKSWLYLRTLKRGEEEFPLRNEQLRQRAKECSQALSLILDIDHGRPVTNVLDLEFDVEQLKDSIDRDKIAIIGHSFGGATVIQTLSEDQRFRCGIALDAWMFPVGDEVYSRIPQPLFFINSERFQYPSNIIRMKKCFLPDRERKMITIRGSVHQNFVDFTFATSKIIGYLFTLKGDIDSNVAISLSNKASLAFLQKHLGLQKDFDQWDSLVEGEDHNLIPGTNINTTNHQAILQNSTGIERPNLD
What is the function of this protein?
Lipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress response (By similarity).  At the lipid-aqueous interface, hydrolyzes the ester bond of fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) (By similarity).  Specifically targets phospholipids with a short-chain fatty acyl group at sn-2 position.  Can hydrolyze phospholipids with long fatty acyl chains, only if they carry oxidized functional groups (By similarity).  Hydrolyzes and inactivates platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), a potent pro-inflammatory signaling lipid that acts through PTAFR on various innate immune cells (By similarity).  Hydrolyzes oxidatively truncated phospholipids carrying an aldehyde group at omega position, preventing their accumulation in low-density lipoprotein (LDL) particles and uncontrolled pro-inflammatory effects (By similarity).  As part of high-density lipoprotein (HDL) particles, can hydrolyze phospholipids having long-chain fatty acyl hydroperoxides at sn-2 position and protect against potential accumulation of these oxylipins in the vascular wall (By similarity).  Catalyzes the release from membrane phospholipids of F2-isoprostanes, lipid biomarkers of cellular oxidative damage (By similarity).
What are the official names of this protein?
Platelet-activating factor acetylhydrolase, PAF acetylhydrolase, 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, LDL-associated phospholipase A2, LDL-PLA(2), PAF 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Note=Associates with both LDL and HDL particles in plasma. Mainly associates with pro-inflammatory electronegative LDL particles.
Protein: OBG_PARDP
Sequence: MKFLDLAKVYVRSGGGGAGCVSFRREKFIEYGGPDGGDGGRGGDVWAEAAPGLNTLIDFRFQQHFFAKSGGHGMGAQRTGASGDDIVLRVPVGTEILEEDQETVIADLTEPGQRVLLAKGGNGGFGNLHFKSSTNRAPRHANPGQPGVERTLWLRLKLIADAGLVGLPNAGKSTFLAAVSNARPKIADYPFTTLHPNLGVVGVDGHEFVMADIPGLIEGASEGRGLGDQFLGHVERSRVLLHLVDGTAEDVALDARTILTELEAYSPALAEKPRVTALNKIDALDPETLAERRAALEAEIGGPVLLMSGVSREGVTEVLRALWSRIAPSRKPAEDREDKPWQP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_LARHH
Sequence: MTIGNTKQTSAAAPKPTYFDHNFKLEATKVLPGEYVATNRDMLLVTVLGSCVSCCLRDSAANVSGLNHFMLPDALMDSEAAATMPARYGMHAMEILINEMIKLGADRQRMEAKIFGGGNVLKGILKSNIGERNVDFVRQYLAKEGIPVMAEDVLDSYPRKLYFFSRSGRVLVKKIKEVHNRTIFERELSYRERLRRMPLDGSIELF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: METE_CHESB
Sequence: MSQIPVATLGVPRIGRRRELKFALEAYWGGESSEGELLAAAAKIRAENWSLQKAAGASIIPSNDFTLYDHVLDMAVTLGAIPEIYGWAGGAVPLDTYFAMARGSQEREACGHSHHDGTGVPALEMTKWFDTNYHYMVPEFDADQTFRLASLKPVEEFDEAKRQGIHTRPVLLGPVSFLKLGKRRDGGDPLELLPRLVPVYAELLGKLLRAGADWVQIDEPCLVLDLTERERRAFTIAYDALAATGGPKLMLATYFGGLGDNLPTAAALPVAGLHLDLVRAPDQLQDVLSAAPEERVISLGVVDGRNIWRTDIAALLDRLGPIVKGNPGRFQLAPSCSLLHVPLDLSIETGVDPELRSWLAFAVQKVEELSILSHALSADRSLVQSLIDMASRALAVRASSTRVNDPHVAGRLSAVTPEMAKRSEPFSERRKLQQERLNLPAFPTTTIGSFPQTAEVRQARAACAKGELSEAGYDGFLKGETEKAIRWQEEIGIDVLVHGEFERNDMVQYFSEQLSGYAFTKQGWVQSYGSRCVRPPIIFGDVSRPQPMTVDWATYAQSLTDKPVKGMLTGPVTMLQWSFVRDDLPRETVCRQIAFALRDEVSDLEAAGIGVIQIDEPALREGLPLREAERPAYLDWAVECFRLASSGVKPETQIHTHMCYAEFNDIIDAIAAMDADVISIETSRSKMELLRAFRAFRYPNDIGPGVFDIHSPRVPPADEMADLLRKAEDGLDPRQIWVNPDCGLKTRKWEEVRFALANMVEAARQMRAG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: PAT08_SOLTU
Sequence: MATTKSFLILIVMILATTSSTFASLEEMVTVLSIDGGGIKGIIPGTILEFLEGQLQKMDNNADARLADYFDVIGGTSTGGLLTSMITTPNENNRPFAAANEIVPFFFEHGPHIFNSSTGQFFGPKYDGKYLMQVLQENLGETRVHQALTEVAISSFDIKTNKPVIFTKSNLAKSPELDAKMYDICYSTAAAPTYFPPHYFTTNTINGDKYEFNLVDGAVATVADPALLSISVATRLAEKDPAFASIRSLNYKKMLLLSLGTGTTSEFDKTYTAEETAKWGAIQWMLVIQRMTDAASSYMTDYYLSTVFQAQNSQKNYLRVQENALTGTTTEMDDASEANMESLVQVGENLLKKPVSKDNPETYEEALKRFAKLLSDRKKLRANKASY
What is the function of this protein?
Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens.
What are the official names of this protein?
Patatin-08, Patatin group D-1.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Vacuole.
Protein: Y2595_SACS2
Sequence: MTYWLVPIQEDMWDVIRDKGIYGYKENLEEFIKEGDYIIIYVSKYYAKRYGGKIVGIVKVLSNWYEDQTPIYPEETVRNKGIYIYRVKVEPVVIGECDMKKILDKIRFIEDKGQIAKYLRNAPANLKRPIPESDAKIVEECLKESLLNI
What are the official names of this protein?
UPF0310 protein SSO2595.
What is the protein family that this protein belongs to?
Belongs to the UPF0310 family.
Protein: SYT_PARXL
Sequence: MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKIDGELVDTSALIDHDVALAIVTEKDADGLDIIRHSTAHLLAYAVKDLYPEAQVTIGPVIDNGFYYDFAYNRPFTPEDLEKIEKRMQELAKKDEPVSRRVVSRDEAVDYFKSIGEKYKAEIIESIPATDEIKLYSHGGFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTKKEDQEAYLHMLEEAEKRDHRKLGKQLDLFHMQDESPGMVFWHPRGWTLWQQVEQYMRRRVNDAGYLEIKTPMIMDRSLWEASGHWQNYRENMFTTESEKRDYAIKPMNCPGHVQVFNHGLRSYRDLPLRYAEFGSCHRNESSGALHGLMRVRGFVQDDAHIFCTEDQFISESIAFNTLAMSVYKDFGFDHVEIKLSLRPDARAGTDETWDRAEQGLREALTACGVTWEELPGEGAFYGPKVEYHIKDALGRSWQCGTLQLDMVLPERLGAEYVAEDNSRRRPIMLHRAIVGSMERFLGILIEHHAGAMPAWLAPMQVVVMNIAESQTEYAQSLAQSLQKQGVRVAADLRNEKISYKIREHTLEKVPYLLVVGDKEREAQTVAVRARGGVDLGVMPLDTFIERLRQDVQSFN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGI_NITOC
Sequence: MKIIQTFFIITLLWLSQGVQAERVKDLAAIAGVRSNQLVGYGLVVGLSGTGDQVTQISYTRQSLRNMLREFGIIMPPGVNLQPKNVAAVSIHAQLPPFAKPGQSIDITVSSLGNAKSLRGGSLLLTPLKGADGRVYAMAQGNLIVGGFGAEGNDGSRVTVNIPSTGRIPNGATVERGVPNPFNNGGPIILNLHAADFTTANRVAAAINSAIGAGTARPLDGASIQVNAPAVPAQRVSFVSLLENLEVDPGEAPAKIVINSRTGTVVIGQHVRVQPAAVSHGRLTVTITANPAISQPPPLSGGQTAVVPRTDIDIQEEGSRMFLFAPGVSLGEIVRAVNQVGAAPGDLVAILEALKQVGALSAELVVL
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: YJY8_YEAST
Sequence: MFSDLCDAGLLESLCLMRMCRHLTRTGWSLKCLCSWSLLVPSGSSHCECFVSGLKKYSLFLDLLYLTVHGVGSPVLDATSDGIGASLWCRSRLCVGISTTMIIQVLFLLRSKGKRYDTRS
What are the official names of this protein?
Putative uncharacterized protein YJR018W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TM237_BOVIN
Sequence: MGKKQVRPPRALPPVPSAIQDDIPLSRPKKKKPRTKTPLASASSEGLVQTAVHRPPEGSEPPTKDSIEHQEAPVQRRQKKTRLPLELETTLTQKKTASPSLLPNENGINVEPDEEPVIQKPRRKTKKTQPAELHYANELGVEDEDIITDEQSSPEQQSVFTAPTGISQPVGKVFVEKSRRFQAADRAELIKTTEKIDVSMDMKPSWTTRDVALSVHRAFRMIGVFSHGFLAGCAVWNIVVIYVLAGDELSDLSNLLQQYKTLAYPFQSLLYLLLALSTVSAFDRIDFAKTSVAIRNFLALDPRALASFLYFTALVLSLSQQMTSDRIHLYTPSSVNGSLWAEGIEEQVLQPWIVVNLVVAVLVGLSWLFLSYRPGMDLSEELMFSSDVEEYPDKGIKVSS
What is the function of this protein?
Component of the transition zone in primary cilia.  Required for ciliogenesis (By similarity).
What are the official names of this protein?
Transmembrane protein 237.
What is the protein family that this protein belongs to?
Belongs to the TMEM237 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes at the proximal region of primary cilia were observed, consistent with localization to the transition zone. Anchored to the transition zone by RPGRIP1L (By similarity).
Protein: JZT40_CHIGU
Sequence: MKVSVLITLAVLGVMFLLTSAEERGSDQMDSPAWLKSMERIFQSEERECRWLFGGCEKDSDCCEHLGCRRTKPSWCGWDFTFGK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U21-theraphotoxin-Cg1c, U21-TRTX-Cg1c, Jingzhaotoxin-40, JZTX-40.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 05 (F4a) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DDX4_MOUSE
Sequence: MGDEDWEAEILKPHVSSYVPVFEKDKYSSGANGDTFNRTSASSDIGESSKKENTSTTGGFGRGKGFGNRGFLNNKFEEGDSSGFWKESNNDCEDNQTRSRGFSKRGGCQDGNDSEASGPFRRGGRGSFRGCRGGFGLGRPNSESDQDQGTQRGGGLFGSRKPAASDSGNGDTYQSRSGSGRGGYKGLNEEVVTGSGKNSWKSETEGGESSDSQGPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMMRDGITASRFKELQEPECIIVAPTRELINQIYLEARKFSFGTCVRAVVIYGGTQFGHSVRQIVQGCNILCATPGRLMDIIGKEKIGLKQVKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLLFSATFPEEIQRLAGDFLKSSYLFVAVGQVGGACRDVQQTILQVGQYSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRCGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDTDSDNHLAQPLVKVLSDAQQDVPAWLEEIAFSTYVPPSFSSSTRGGAVFASVDTRKNYQGKHTLNTAGISSSQAPNPVDDESWD
What is the function of this protein?
ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity (PubMed:20439430, PubMed:28633017).  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (PubMed:20439430, PubMed:28633017).  Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (PubMed:20439430, PubMed:28633017).  Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs (PubMed:28633017).
What are the official names of this protein?
ATP-dependent RNA helicase DDX4, DEAD box protein 4, Mvh, Vasa homolog.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX4/VASA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis.
Protein: TGT_BORHD
Sequence: MFNIIKNDKNSNARIGVLELPHGKVTTPCFMPVGTLGVMKALKHDVLEKLGCNLMLANTYHLYLRPGIDVIKEYGSLHNFTTWNKNFLTDSGGFQVFSLSNFRKIETEGVDFKSHIDGSRHYFTPESVFKMQEIFESDIIMALDICSSYGIDYSEASLYANITTSWARRTLRAYENRKEGYDGFLFLITQGNFFKDLRKRSTEAILELNSPGIAIGGISVGEPRDKYLEILEYNSSLIPKDKPKYVMGIGTPHYILDAIYYGIDIFDCVNPTRIARHGSLLTDNGILRIKRAGFNVDTSPIEQDCSCTLCTRYSRGYLRHLIKSGETLGVMLASEHNIHYMFRLIQKARNAIMNDDFTQFRKLYLSKYDEGNFNE
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PSBH_GOSHI
Sequence: MATQTVEGSSRSGPRRTVVGDFLKPLNSEYGKVAPGWGTTPLMGVAMALFAIFLSIILEIYNSSVLLDGISMN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CARA_HALS3
Sequence: MSDAYLALETGDVVEATARAPGMARGELVFTTAYTGYEESLTDPSYEAQVLTFAYPLIGNYGVRPERTESDRVHPSAVVARELTDDVADWLRTEGVPAVDGIDTRDLVLDIRDGGAMQVGIAAGPDASPATARAQLADCPRLSARTEIGAHVSVDTAETHGNGDTTVALVDCGAKRSIIDAFVARGATVHRLPYDATPADIAAVDPDLLFISNGPGDPANFDAAEHLVDEYIGTVPIAGICLGQQIVARALGGDTEKMDFGHRGVNQPVLDHDSGRVVMTTQNHGYTVADPGDLTVTQVNVNDGTPEALDSAPLDVLTRQYHPEANPGPHDTRGFFDDVLAMADASYTPATAD
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: ATP6_EHRCR
Sequence: MSANPLDQFKISTIFKLPSIGGYNIDFTNASLFMVLSTLIISLFCYIGLRKENILPNSMQLIIEAIYNFIVSTIESNVGRKGLQYIPLVFTIFTFIATCNLLGVLPLGFTVTSHIAVTFAISMVVFISVTAIGFKHQGIHFLRILLPKGTPGWLAPMMVFIELFAYCARPVSLSIRLAANMIAGHTIIKVIAGFVIKMNIFLTPLPMAFIIILIGFEIFVAILQAYIFTVLTCVYLSDAINEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NQRB_HAEIG
Sequence: MGLKNLFEKMEPAFLPGGKYSKLYPIFESIYTLLYTPGTVTHKNTHVRDALDSKRMMITVFLALFPAIFYGMYNVGNQAIPALNQLGNLDQLIANDWHYALASSLGLDLTANATWGSKMALGAIFFLPIYLVVFTVCTIWELLFSVVRGHEVNEGMFVSTILFALIVPPTLPLWQAALGITFGIIVAKEIFGGVGRNFMNPALAGRAFLFFAYPAQISGDTVWTAADGFSGATALSQWSQGGQGALQHTVTGAPITWMDAFVGNLPGSMGEVSTLAILIGGAVIVFTRIAAWRIIAGVMIGMIATSTLFNLIGSETNPMFSMPWHWHFVLGGFALGMVFMATDPVSASFTNTGKWWYGALIGVMAVLIRTVNPAYPEGMMLAILFANLFAPIFDYIVVQANIKRRRARTNG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-NQR subunit B, Na(+)-translocating NQR subunit B, NQR complex subunit B, NQR-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FABH_RHILO
Sequence: MIRSVVRGMGAALPRRIMKNADFEGMVETSDEWIVQRTGIRQRHIAADDETTASLGEAAARAALANAGLTPGDIDLIVLATSTPNNTFPATAVEIQNRLGMHHGFAFDMQAVCSGFVYAVTTADLYIRGGLAKRVLVIGSETFSRILDWNDRSTCVLFGDGAGALILEAGEGAGTIADRGVLAASLRSDGVHKDKLFVDGGPSTTGTVGHLRMEGREVFKHAVGMITDVIEATFSAAGISADDLDWFVPHQANKRIIDASAKKLGIAEQKVVVTVDLHGNTSAASVPLALSVAVADGRIKKGDLVLLEAMGGGFTWGAVLVRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP1_BUCBP
Sequence: MTCIFIKNINEINKMRLVGKLVADVLDMIKEYIVPGITTEELNNICHNYITYKQHAKPACLGYQGFPKSICTSINDIVCHGIPNKNSILKNGDIINIDVAILKDKYYSDASKMFFVGKPTELGKKLCYVAKKSLYLALYTIRPGINLQKLGKVIQNYVKKQNFSIVKEYCGHGIGRSFHEPPQILHHNYYKSNTTILQSGMTFTVEPMINSGSCEVQCTNDGWTVKTKDKSLSAQYEHTILVNEEGCEILTLQKGEQISRILKNLT
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.