PharMolix/UniProtQA huggingface dataset:
Protein: GPMI_NEOYE
Sequence: MKKKIVHPIVLAILDGWGHTNIQQGNAIKIAKTPTIDSLIQAYPSTLLAASGQEVGLPKGQMGNSEVGHTTIGGGRVIQQELVKIGNSIVDNSFFNNLELNEACEYANNNKASLHLIGLCSNGGVHSHIDHLLALIDLADSKQVTNLYLHLITDGRDTSSNSAKYFIKIVADHIEHKQFATISTISGRYYAMDRDFRWSRTQAAYNILTSNNSIKLNASVNYGDLIDHYYNKGISDEFIPPSRINLGSIKDNDAIVFFNFRPDRMRQIVQAFVQKPFNCFATKPLYNLRVVTFTNYDTSLNTTIAFHPHILNNFLGEVLYKYGLKQFRVSETEKYAHVTYFFNGGAEEPFPGEDRELVSSPDVTTYDLSPDMSAELVTQKSISAIKKAIYSCIVINYANADMLGHTGKLKETIQSIETVDRCITELLDAVSKLNGTLIITADHGNAECMFTDEGNPCTAHTTNLVPLILIEGEQEAISGHGGQVKLRNNGSLADIAPTILDILHLKKPPEMTGKSLIINSRYETRNIEKTSIEL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IL6_MUSPF
Sequence: MNSLSTSAFSPVAFSLGLLLVMATAFPTPGPLGGDSKDDATSNRPPLTSADKMEDFIRFILGKISALKKEMCEKYNKCEDSKEALAENNLNLPKLAEEDKCFQSQFNQETCLTRITTGLQEFQIHLKYLEANYEGNKNNAHSVYISTKHLLQKLRPMNRVEVTTPDPTTDSSLQALFKSQDKWLKHVTIHLILRSLEDFLQFSLRAIRIM
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity).  'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity).  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity).  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CF123_HUMAN
Sequence: MGTAVGPHHSPAPHDSALPARLLTSDFPYGRSCQIEQVKYSVPDTGLFQHWEGSIPT
What are the official names of this protein?
Uncharacterized protein encoded by LINC01558, Protein HGC6.2.
Protein: MNMA_SHIFL
Sequence: MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIKVIFDEPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG4B_ARATH
Sequence: MKAICDRFVPSKCSSSSTSEKRDISSPTSLVSDSASSDNKSNLTLCSDVVASSSPVSQLCREASTSGHNPVCTTHSSWTVILKTASMASGAIRRFQDRVLGPSRTGISSSTSEIWLLGVCYKISEGESSEEADAGRVLAAFRQDFSSLILMTYRRGFEPIGDTTYTSDVNWGCMLRSGQMLFAQALLFQRLGRSWRKKDSEPADEKYLEILELFGDTEASAFSIHNLILAGESYGLAAGSWVGPYAVCRSWESLARKNKEETDDKHKSFSMAVHIVSGSEDGERGGAPILCIEDVTKTCLEFSEGETEWPPILLLVPLVLGLDRVNPRYIPSLIATFTFPQSLGILGGKPGASTYIVGVQEDKGFYLDPHDVQQVVTVKKENQDVDTSSYHCNTLRYVPLESLDPSLALGFYCQHKDDFDDFCIRATKLAGDSNGAPLFTVTQSHRRNDCGIAETSSSTETSTEISGEEHEDDWQLL
What is the function of this protein?
Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.  The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine (By similarity).  Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.  In addition to the protease activity, also mediates delipidation of PE-conjugated ATG8 proteins (By similarity).
What are the official names of this protein?
Cysteine protease ATG4b, Autophagy-related protein 4 homolog b, AtAPG4b, Protein autophagy 4b.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_YERPN
Sequence: MKVGIIGAMEEEVTLLRDRIENRQTLARAGCEIYTGQLNGIDVALLKSGIGKVAAAMGTTLLLEHCQPDLVINTGSAGGLDSSLKVGDIVVSNEVRYHDADVTAFGYEPGQMAGCPAAFVADEDLIALAENCIQQLKLNAVRGLICSGDAFINGAEPLARIRAAFPTVAAVEMEAAAIGHVCYLFNTPFVVVRAISDVADQASHLSFEEFLVVAAKQSTLMIKAMLTTLAQRG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: PSBF_HYDMC
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL20_CAMHC
Sequence: MARVKTGVVRRRRHKKVLKLARGFFSARRKHFRKAKEQVERSLVYSYRDRRNKKRDFRRLWIVRINAACRLNDISYSKFINALKKANIELDRKVLADLAMNDAAAFSAIVAQAKKVM
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TRMN6_PHOLL
Sequence: MKQKRLLRRDGFTFKQFFVGHDRCAMKVGTDGVLLGAWTPVSDKKAILDIGCGSGLIALMLAQRTDENTKIDAVELDTEAALQAQDNAEQSPWQRKIDVYQQDIGDFAEQYSQCYDLIVSNPPYFEPAVACRNEAREQARYTGSMTHQQLLQYAETLITADGLFCVVLPYAIGEEFETMACHQGWFSHHRVNIRDRQGKPLHRMLLAFSRKEKTGLISELTIRQPDGAYTQEFQQLVTDFYLYY
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_FRAAA
Sequence: MTAESDSPDGPVSAGTGRPVRLSLTRRAARPARHLADLSRDERRQVAVALGQPAFRADQVSRHYFARLVDADETDAMTDLPENARGPLLEALLPRLLVPARTLSCDDGLTRKTAWRTADGALLESVIMRYPDRATVCVSSQAGCGMGCPFCATGQGGLTRNLSTAEIVEQVVHAARVLRRQELAGGQGRLSNVVFMGMGEPLANYTAVTAALRRLIAPSPEGLGLSARGLTVSTVGLVPAMRRLAGEGLPVTLAVSLHAPDDELRDELVPINTRWPVAEVLAAAWEYAEVTGRRVSIEYALIDGVNDDVARADALATLLAGRLAHVNLIPLNPTEGSSWQASAPAGQRAFVRRLRERGIATTVRDTRGREIAAACGQLAAEPAGRARRVESARPVESARPVGVAGAASGSPAHGSRVLR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_BDEBA
Sequence: MMSQTELLRKKSHPVDQALTPEEIQQYLTVLDGWSLQGLHIAKSFEFKNYYQTIAFVNAIAFIVHTEDHHPELEVGYNRCVVKFYTHSVNEGLGGISENDFICAAKIDALAGNQFAPMSH
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: TXGAA_ETHRU
Sequence: MASFTSFCVLFTFCLLLLAHQARSGERQYKTESRNGKCVGEDDQLHAPTEVWYNDNDCSEHTCVNDDTGYYEIIRRCTLIAYPDECHMINGTGPRYPQCCCKVTCELD
What are the official names of this protein?
U-scoloptoxin(16)-Er10a, U-SLPTX(16)-Er10a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRU2_BRANA
Sequence: MARLSSLLYFSITVLIFLHGSTAQQFPNECQLDQLNALEPSHVLKAEAGRIEVWDHHAPQLRCSGVSFVRYIIESQGLYLPSFLNTANVSFVAKGQGLMGRVVPGCAETFQDSSVFQPGSGSPFGEGQGQGQQGQGQGQGQGQGKGQQGQGKGQQGQSQGQQGQGQGFRDMHQKVEHIRSGDTIATHPGVAQWFYNNGNQPLVIVAVMDLASHQNQLDRNPSQFYLAGKNPQGQSWLHGRGQQPQNNILNGFSPEVLAQAFKIDVRTAQQLQNQQDNRGNIVRVQGPFGVIRPPLKSQRPQETEANGLEETICSARCTDNLDDPSNADVYKPQLGYISILNSYDLPILRVLRLSALRGSIRQNAMVLPQWKSKSNAVLYVTDGEAQIQVVNDNGDRVFDGQVSQGQLLSIPQGFSVVKRATSDQFRWIEFKTNANAQINTLAGRTSVMRGLPLEVIANGYQISLEEARRVKFNTIETTLTHSSGPASYGRPRKADA
What is the function of this protein?
This is a seed storage protein.
What are the official names of this protein?
Cruciferin BnC2, 11S globulin, 12S storage protein.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: HIRA_XENLA
Sequence: MKLLKPSWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMPPMLKEEDEKNENIPKMLCQMDNHLACVNCVRWSNNGAYLASGGDDKLIMVWKRSGYIGPSTVFGSSSKLANVEQWRCLSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNALKFPEIISTLRGHSGLVKGLTWDPVGKYIASQADDHSIKVWRTMDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKTSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAYLDFSQDELGDPLSEEEKNNIHQSTYGKSLAITTEPQLPNTVIENPEMLKFQQRQQLQQDGEHMVQAQMEAPIHNMASMMNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPISGSLPGSMMSSQSNQQLISLDSNTTSSSGALKSNVELVGNNTKPAEETANKESGNVSSSSPVAPTSITAQPKIEPMKALDSRFTERSKATSGTAGVAHLNQTAVDRLKEQNVTKDSKPRVVESSSDSEEKIPASKQLSKRKGEADADLAEKRKKGRPRKESQRLMSVSLTVQSQVASTSEKELTCVTTSSLTLRLPTPTPQKSFTLQLSSDPSMYIEVENEVKTVGGNKLSQLKCHREGKEWEAVLTSRIVAAAGSKEVVCVACEKRMLSIFSGSGRRIFPPIILPSPISTLQCTGSYVMALTAAAALSVWDVQNQNIIIKNESLQPLLSGNDLTVSQTLLTKRGIPVLSLSNGKAYCFSPSLSTWSLVSDKQDSLAQCADYRSCMPSQDAVMCSGPLAIIQGRVSNAGRQAAHLFTMPHLVQKETTMAYLENQVAAALMLQSSQEYRHWLLIYAQYLVNEGFEQRLREVCQDLLGPVHRSSDSQWESRILGLWKRELLKELLPLIGQNLRFQRLFTEYQEQLDILRDK
What is the function of this protein?
Required for the periodic repression of histone gene transcription during the cell cycle (By similarity).  Required for replication-independent chromatin assembly.
What are the official names of this protein?
Protein HIRA.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COG6_PHANO
Sequence: MSVSYFQERGTPASGDVLSPATTSLGGASRGANALSSRITSVLSASYADLEIRDALETLDTRGVRNTAETRRQIRLDVQKEVIECNGEIVKDFGQVAEQLKRIGTAISSLNSYCADMRSHIAAANKETGPVLEEATGLINQRKQVESKQQILQAFNSHFLISDEEATVLTSTAEPVNEEFFQVLTRVKKIHHDCQVLLGTEDQRLGLEILEQSSKQLNAAFQKLYRWIQREFKTLDLENPQISASVRRSLRVLAERPTLFQSCLDSFAEARESILSDSFHSALTGSASDAEHIATKPIEFQAHDPLRYVGDMLAWVHSTTVSEREALENLFISDGDEIKRSIQEGLESEPWLKDEEAEIFDGRKALSQLVGRDLASVARVLRQRTEQVVQSHDDATLAYKIANLIGFYKGMFAKLLGTDSDVLEVFTTLEASAMRQFRANMRDYVAAVQSDIAVPPQDLSPPDFLDDALQTLKVLAKSYDTSSAGAEDQEQGFQAVLAEALDPFMSGCVNLQKGLQQPDSAVFAINCLFAAKDVLSAFTFASERVEEMEDTISEQVAQLVDYQHEYLLHESGLATLLEALEPITDDEESLKTIPELEPFKRDALVAASQQLDEFLPSALIDAAENLKRLKNRKMIQDITEEAAASFCEDFEVVESKIIAADDLTYDEDKEDEEQEPGLRDLFPRTSGEIRVLLS
What is the function of this protein?
Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking.  COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 6, COG complex subunit 6, Component of oligomeric Golgi complex 6.
What is the protein family that this protein belongs to?
Belongs to the COG6 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: SYM_VIBPA
Sequence: MANDPRHLPSRKLLVTCALPYANGSIHLGHMLEHIQADIWVRYQRLRGNTVNFICADDAHGTPIMLKAQQMGITPEEMIAAVSEEHQKDFAGFDISFDNYHSTHSEENRELASHIYLELKKNGFISSRTISQLFDPEKEMFLPDRFVKGTCPKCKSEDQYGDNCDNCGETYSPTELINPKSAVSGATPVMKDSEHFFFDLPQFESMLKEWTRSGSLQSETANKMQEWFESGLQQWDISRDAPYFGFEIPGEKDKFFYVWLDAPIGYMGSFKNLCNKRDDLDFDEYWNKDSKTELYHFIGKDIVYFHSLFWPAMLEGSGFRKPNNVFVHGYVTVNGAKMSKSKGTFVKASTYLDHLDPECLRYYYAAKLNSRIDDLDLNLEDFTQRVNADVVNKIVNLASRNAGFIAKRFEGKLSDNFAEPELYNEFVAAADRIAELFEAREFGRAIREITALADKANQYVDEKAPWVVAKEEGKDQELQEICSVGINLFRVLMTYLKPVMPALAARTEAFLNQELTWEGIAQPLTGHEITKFKALFNRIDPKNIEAMIEASKEDAAAEMAAKEKAEAAKTETELSKDPIADEIEFDTFAQVDLRIARIISCEEVPKANKLLKFQLDIGGETRQVFSGIKSAYKPEELEGKLTVMVANLKPRKMKFGMSEGMILAAGPGGSDLWILEPHEGAQPGMRVM
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_MYCSP
Sequence: MKVRASIKRICKDCKIIKRHGVNRVICINFKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SOMA_LATCA
Sequence: MDRVVLLLSVLSLGVSSQPITDSQRLFSIAVSRVQHLHLLAQRRFSEFESSLQTEEQRQLNKIFLQDFCNSDYIISPIDKHETQRSSVLKLLSISYRLVESWEFSSRSLSGGSAPRDQISPKLSELKTGILLLIRANQDGAEMFSDSSALQLAPYGNYYQSLGADESLRRTYELLACFKKDMHKVETYLTVAKCRLSPEANCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RCM1_SCHPO
Sequence: MDFYNHAANILSDLSKKKGSIKQLAFNSKKHDPKRTYALVCETLKYKPVLDEIIARSELLVLEKKLKENLARVLVHDLLMSKRGLSISNGPIKECILRHKTRLNAEFVKLKVKKGVKSHEELALKNPVSLPRWLRINTIKSTKDEVLQGLGLDKVSSIEELGPDKFYIDDCVENLIAIDPSFPIVENSLYKEGKVIIQDKASCFPAAVLAGLTGHVGDIIDGCAAPGNKTTHLAACFPKSHIFAFERDAKRVQTLRKMVGISGANNVTIEHQDFTLTDPKSDLYRNVTHILLDPSCSGSGIVSRQDYLLGNEQDVTEDTERLENLCSFQSTILKHALQFPNCRHVTYSTCSVHRLENEQVVCEVLSQEPDWKCNSLTKTLPNWKTRGIPEYCAQPSMAEGMIRCKPGAGGTIGFFVANLYHPQREQETFKMYKNDDDTKKRKRKKKKKEVKKKARIQGEE
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of a cytosine in 25S rRNA.
What are the official names of this protein?
25S rRNA (cytosine-C(5))-methyltransferase rcm1, rRNA m(5)C methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YIDC_LEPIC
Sequence: MEDRQTRLFLALILSMGIWMGVNYFFFPNTSTKKNTETKQTQSDKTSENTKQQITSGKTKESNSADPVVQKEKITPFDTKKSFIVTDSYIVEFSSLGGKISKFYMKDFTGPNGELIQVARKNPETVVVDGKSYQAVELSRDKGFDFNFSDSLVEISDSPWNYIQFSLTEDKINHSISFSAVSPDRSYQLKKEFRFYPSENYFKLSISIINFSKEKLSFASQKNVRYLRTFGSLGPYPKDRPLSDRDTANFFRFYYLGGSFQDTLDGSSSVGFWSSVGNFFTGNSGTDESFSIKTDKESGVDFAGTGSRYFIAVADPLDHKPHGIVLDNRPKNESGAVLVYDNILLNPGENYNLDFASYIGIRESEGMAFKNPEFDPSQSKNSPFVGLSSDLNKSFNQGITTPFRNGIIWILKQIYRFTIPNYGWSIIIFAILFKLVFYPLNQKQADSMKKMQELSPQLKTINEKFANDPKMRQQKTMELYKKNNVNPVGGCLPMVIQIPIFIALYTAFSDTIDLWNSPFLWVKDLSEPDVIWTSPAIPYFTQTGIGLNLLALLMVGTQVFQTRMTSVSMDPNQKMLMYVMPVMMLYIFWNMPSGVTLYWTFQNVLSIGQQWITNHLKKTEEKKKAKV
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AQDA2_RHOER
Sequence: MFQTVTAPTGVWRGRVTGDVTVFHGIQYARADRFAPPQRCEPQLQHLVEVPEPGPIAPQSPSRLEGVMGAPSSLKQSEACLTVTVTTPHLAQPGSLPVLVWLHGGAFLSGSGAWEQYGAEQLVRETGIVVVSVNYRLGVLGYLCAPGISSGNLGLLDQITALEWVRDNIEAFGGDNGRVTLDGQSAGAHSIVAMLGIDRARSLFSRAIIQSAPLGLGFHSVEQARRAAEIFEEELGSDPRRAVVTDILAAQARTAHRLAGRGAMNSAPPFLPVHGMAPLPFVGEWNGKVAANAARRKILIGNTRDEMAAFFGPHPVFSAMRRVPLAGPQLAGAIQRRVQKVVFDNPVQEFADRFASAGASVWRYGIGPLHPDNPFGACHCIDIPLLFGDGDTWRDAPMLRPLSPKEIGESGTRTRRYWGEFVHTGRISDPAWPMHRPKSRYAHLLTDETIGGSA
What is the function of this protein?
Involved in the degradation of the Pseudomonas aeruginosa quorum sensing signal molecules HHQ (2-heptyl-4-quinolone) and PQS (2-heptyl-3-hydroxy-4-quinolone) to anthranilic acid.  Probably catalyzes the hydrolysis of N-octanoylanthranilic acid to anthranilic acid.
What are the official names of this protein?
Probable N-octanoylanthranilate hydrolase AqdA2.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
Protein: RUGA_PELSA
Sequence: KGAAKGLLEVASCKLSKSC
What is the function of this protein?
Stimulates insulin release by BRIN-BD11 cells in vitro.  Has antibacterial activity.
What are the official names of this protein?
Rugosin A-like peptide.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ABDH_ESCF3
Sequence: MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAAVRAADAAFAEWGQTTPKARAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHTAPSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLEHVSKAVEEAKGTGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTAFDNEEQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVKH
What is the function of this protein?
Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA).  This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal.  Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Gamma-aminobutyraldehyde dehydrogenase, ABALDH, 1-pyrroline dehydrogenase, 4-aminobutanal dehydrogenase, 5-aminopentanal dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
Protein: DUT_ECOK1
Sequence: MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDNFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: GTRA_BPP22
Sequence: MLKLFAKYTSIGVLNTLIHWGVFAFCVYGMHTHQALANFSGFVIAVSFSFYANARFTFNATTTTLRYMMYVGFMGTLSAVVGWMADQCSLPPLITLITFSAISLVCGFIYSRFIVFRDIR
What is the function of this protein?
Involved in O antigen modification.  Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity).
What are the official names of this protein?
Bactoprenol-linked glucose translocase.
What is the protein family that this protein belongs to?
Belongs to the GtrA family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: Y2103_GEOKA
Sequence: MTFAAPMSSKEARQMIRNNEWVKPTAGVANGYTQANLVVLPKELAFEFLLFCQRNPKPCPVLDVTEPGSWEPSMVAPGADLRVDLPKYRVYRNGELTEERTDIIDLWDKDMVGFLLGCSFTFEHALVNNGIPVRHIQENCNVPMYKTNIPCVKAGRFEGPMVVSMRPIPHKDVVRAVQVTSRFPSVHGAPIHIGDPKLIGIHDIYKPDFGDPVTIREGETPVFWACGVTPQAVAMEVKPDIMITHAPGHMFITDLRDEQLGVL
What are the official names of this protein?
Putative hydro-lyase GK2103.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: ECFA2_CLOAB
Sequence: MPIKIENLTYTYMPGTPFEKKALDNVNITIEDGEFAVFIGHTGSGKSTLIQQINGLLKPTSGSIFIDDVDITDKSVKLNDIRKKVGLVFQYPEYQLFEETIEKDIAFGPRNMGLSEEEVSTRVKKAMKMVGLEYNDFKDKSPFELSGGQKRRVAIAGVVAMEPKVLILDEPTAGLDPKGRDDILYEIKKLQKEYKMTIILVSHSMEDVAKVADKIFVMYDSRCILSGNLDEVFNEIDTLEKVGLAVPKVTYLVRKLREKGFDISKDIFTIEAAKKEILRVLESAKR
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.