PharMolix/UniProtQA huggingface dataset:
Protein: RS8_BUCAT
Sequence: MSMQDPVADMLTRIRNGQLANKYSVKMPSSKLKKSIIQLLKEEGYIKDYNVTGDTKLELEVFLKYFQGKSVVDMIQRISRPSLRIYKNKNNLPKVMSGLGIAVISTSKGVMTDRMARQEGLGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RR11_ACOCL
Sequence: MTKTIPRIGSRRNGRIGLRKTGRRIPKGIIHVQASFNNTIVTVTDVRGRVVSWSSAGTCGFKGTRRGTPFAAQTAAGNAIRTVVDQGMQRAEVMIKGPGLGRDAALRAIRRSGILLNFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TFP11_CHICK
Sequence: MSMSHLYGTDGEDGVEMENFEVSDWDLQNEFNPHRHRHRQTKEEATYGVWAERDSDEERPSFGGKRSRDYSAPVNFISAGLKKSAAEDVSDEDSDEDEKPVKQEEIPKEFVPKKLKTGGNFKPSQKGFVGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTSQSLQDFPVVDSEEEAEEEFQKELSQWRKDPNGGKKKPKYSYKTVEELKAKGRINKQLSTPQKELSQVKVIDMTGREQKVYYSYSQISHKHNIPDDNPQQLLGKDSKPQGFALPELEHNLQLLIDITEQEIIQSDRQLQYERDMVVNLTHEIQKMSEILSHEETAISNLSKVLDMVEECERRMQPSCENPLTLDECAKIFETLQDKYYEEYRMSDRVDLAVAIVYPLMKDYFKNWDPLKDCTYGTEIIAKWKSLLENDQLLSHGGQDLSTDAFHRLMWEIWMPYVRNIVAQWQPRNCGSMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWNPLTDTVPIHSWIHPWLPLMQARLEPLYSPIRNKLANALQKWHPSDSSAKLILQPWKDVFTPGSWEAFMVKNIVPKLGMCLNELIINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFPKWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSIKDKFNEALDIMNRAVSSSVGGYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGMAASSVPMNFKDLIQTKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK
What is the function of this protein?
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
What are the official names of this protein?
Tuftelin-interacting protein 11, Septin and tuftelin-interacting protein 1, STIP-1.
What is the protein family that this protein belongs to?
Belongs to the TFP11/STIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RF1_BREBN
Sequence: MFTRLSAVEERFEEVTNLLCDPDVISDTKRLRELSKEQSSLEETVTTYREYKSVVSQIDDAKAMLEEKLDDEMREMVKLELNELSARKEQLEDRLKILLLPKDPNDEKNVIVEIRGAAGGDEAALFAAVLFRMYTRFAERNAFKIEVLEASPTDIGGYKEIVFSLSGRGAYSKMKFESGAHRVQRIPATESGGRIHTSTATVLVLPEAEDVEVEVHEKDIRIDTFCSSGAGGQSVNTTKSAVRVTHIPTGIMVSCQDEKSQHSNKDKALRVLRARLYDFYMQQQNAEADATRKSLVGTGDRSERIRTYNYPQSRVTDHRIGLTLHRLESVLEGEMDEVIDNLIMHEQTELLKSHAHSA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN330_DROME
Sequence: MPKKKTGQRKKAEKQKLRLKEIRSREVPLADLPCNAPMECDKCEKKQKSRAFCYFCQSIQRLPICAQCGKIKCMLKTGDCVVKHPGVYTTGLGMVGAICDFCEAWVCHGRKCLQNHACTCPLQNATCLECERGVWEHGGRIFKCSFCNGFLCEDDQFEHQASCQVLESENYKCQSCNKLGQYSCLRCKTCYCEDHVRRKGFKYDKNKPIPCPKCNYDTSVTKDLSMSTRSHKFGRQQQGGNSDDEEGYGGYYGAGGSGYYGGAASGGYSYGGDDDEDESDGDYDDESDEDDDDDEEEDETTESEPEKETDKKATK
What are the official names of this protein?
Zinc finger protein 330 homolog, Nucleolar autoantigen 36 homolog.
What is the protein family that this protein belongs to?
Belongs to the NOA36 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Predominantly expressed in the nucleolus.
Protein: YKN6_YEAST
Sequence: MYGIILKFTTTDVYSQNKSRRSCDTILPPETSGLFLPPEDIPFESPPSFSSFNPCTALVSFVFICVASSDGPKSNKSSKSPKVVKVFSIPAFVFVTSSLSSKSNSTSSLALLEISFFAMLSNSSICFPLTIF
What are the official names of this protein?
Putative uncharacterized protein YKL136W.
Protein: CCME_VIBVY
Sequence: MNPRRQKRLGIILAILIGVSATIGLMIYALNQNMDLFYTPTELVNGKDDGTKPEVGQRLRIGGMVVMGSVRRDPESLKVRFDLADVGPKVTIEYEGILPDLFREGQGIVAQGVLKDATTVEAFEVLAKHDEEYMPPEIAEAMKKTHAPLQYSEEQKQGSGQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: ARGD_YEAST
Sequence: MFKRYLSSTSSRRFTSILEEKAFQVTTYSRPEDLCITRGKNAKLYDDVNGKEYIDFTAGIAVTALGHANPKVAEILHHQANKLVHSSNLYFTKECLDLSEKIVEKTKQFGGQHDASRVFLCNSGTEANEAALKFAKKHGIMKNPSKQGIVAFENSFHGRTMGALSVTWNSKYRTPFGDLVPHVSFLNLNDEMTKLQSYIETKKDEIAGLIVEPIQGEGGVFPVEVEKLTGLKKICQDNDVIVIHDEIQCGLGRSGKLWAHAYLPSEAHPDIFTSAKALGNGFPIAATIVNEKVNNALRVGDHGTTYGGNPLACSVSNYVLDTIADEAFLKQVSKKSDILQKRLREIQAKYPNQIKTIRGKGLMLGAEFVEPPTEVIKKARELGLLIITAGKSTVRFVPALTIEDELIEEGMDAFEKAIEAVYA
What is the function of this protein?
catalyzes the conversion of N-acetylglutamate-gamma-semialdehyde (NAGSA) to N-acetylornithine in arginine biosynthesis.
What are the official names of this protein?
Acetylornithine aminotransferase, mitochondrial, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TXA2_LATHE
Sequence: MLKLICIAFLVTVLTLVAGEDSLDPAEYGCADDINQEDLLKKNDVCLQCEDLHKEGVVFSLCKTNCFTTQYFTNCVKDLEEAEKEPPE
What is the function of this protein?
May increase the toxicity of alpha-latrotoxin and/or other venom components.  Is non-toxic to mice and to the cockroach Periplaneta americana.
What are the official names of this protein?
Alpha-latrotoxin associated low molecular weight protein 2, Alpha-latrotoxin-associated LMWP2, Latrodectin-2.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: PNP_SHEWM
Sequence: MNPIVKSFEYGQHTVTLETGVIARQANAAVLASMGDTTVLVTVVGKKAEDVGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSENETLIARLIDRPIRPLFPNGFKNEVQVIITVVSVDPEINPDVISMIGTSAALSISDLPFNGPLGVARVGYTNGEYVLNPNVSQLAESDLDLVVAGTQGAVLMVESEAASLPEEVMLGGVVYGHDQQQVVINAINELTAEAGKTKWDWTAPAEDTDLVEKIKGLAEAELTNAYQIADKHERRDAVIALKNAAVAKLVEENADVDLREVDKLLGSLEKKVVRSRIISGSPRIDGREPDMVRALNVMAGVLPRTHGSSLFTRGETQALVTCTLGTERDAQKVDSIMGEYTNRFMLHYNFPPYSVGETGMVGSPKRREIGHGKLAWRGINAVMPTAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTRDGITALQMDIKIEGITKEIMQIALQQAYGARVHILNVMDQAISGHREDISDHAPRITTLKINPEKIRDVIGKGGATIRALTEETGTTIELEDDGTVKIASANGEATKEAIRRIEEITAEVEVGTVYNGKVVRIVDFGAFVTILPGKDGLVHISQIAEERVANVSDYLQVGQEVKVKVMEVDRQGRVRLSMKEAQPKAEAAPAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTP_SALSV
Sequence: MKRVLTALAAALPFAAHAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFTEAMAVHPKGTAIMSPGGLVQDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPAYKDAAGALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATEREELKVSKITVLVLGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLLTAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16_NITSB
Sequence: MVVIRLARFGRKKRPFYRIVVTDSRKRRDSGWIESIGYYNPLTDPVTVKIDEERLNYWLGVGAKMSERVKKLSGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MTR1_THECC
Sequence: MEQILSMNGGSGEQSYANNSIGQSTCLSRSMPVLKQAVLDSCCTNLPETVTMADLGCSSGPNTFYAVSEITSIIYKRCCQLGRSAPEFRVFLNDLPGNDFNTVFQSLPAYQGKLREENGPGFGPLYVAGVPGSFYGRLFPLKTLHFVHSSSSLHWLSQVPPELTDKANPLINKWKIFISKTSPPAVISSYLTQFRKDFSLFLKLRSEEVAPEGRMVLTFRGRTTADPTSDESCLLWDYLGQAFQDLVAEGLVEEERLDTYNTPYYEPHPEEIQAEIEKEGSFTLDRLEVIALPWDSVNGGIKDDRATTAKRMAKAIRAVNESMFRSHFGEDILDPLFHRFIEIMAADTKEVEHVSLVISLIRKA
What are the official names of this protein?
Probable methyltransferase TCM_000168.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: HIS4_PSEF5
Sequence: MLIIPAIDLKDGACVRLRQGRMEDSTVFSDDPVSMAAKWVEGGCRRLHLVDLNGAFEGQPVNGEVVTAIAKRYPNLPIQIGGGIRSLETIEHYVKAGVSYVIIGTKAVKEPEFVAEACRAFPGKVIVGLDAKDGFVATDGWAEVSSVQVIDLAKRFEADGVSAIVYTDIAKDGMMQGCNVPFTAALAAATRIPVIASGGIHNLGDIKALLDAKAPGIIGAITGRAIYEGTLDVAEAQAFCDSYQG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA53B_DANRE
Sequence: MCVAMVIIHTKTLEKKAVDDVTSEASLQPQEPLTMSQGTALFSCGIMDSGRWADVGSVCGVQQRPVGSSLESLWDSMREAGATGGISGLLRDLSLSEASPASAAPPSKRQCRSLSCSDELGCRSSWRPQGSRVWTTVEKRRCHSGGSVQRGVFNPSGFPAMQRSSSFSLPAHSSHLEPFTHGFPFQAFSECPQTPQTLYRSHEQICPAEASSPESTPELQRRSGQSGLARSRSQPCVHNHQKIGVKRRRPADSHKQRPSLDLLKMTQKLQDFHSLSCPGFSGDDKTLPSSSPALLNDTCERAQNDSSADAPIHQSESSSEDALIHQSDSSSADALIHQSESSRPAGKERECLWAGLCSRRGRDLFQLGGELDIEQIERN
What is the function of this protein?
Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (ctnnb1) nuclear localization (PubMed:25183871).  Required for appendage regeneration by regulating cell proliferation (PubMed:19014929).
What are the official names of this protein?
Protein FAM53B, Protein simplet.
What is the protein family that this protein belongs to?
Belongs to the FAM53 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSGA_PSEU2
Sequence: MAKRQLNRRQNWRIEKIQGERAARAAKRESATLETLEGGDLGPEQTGLVIAHFGVQVEVEAQEGEVTGQVFRCHLRANLPALVTGDRVVWRAGNQGIGVIVAQLPRTTELRRPDSRGQLKPVAANVDLIVIVFAPMPEPHANLIDRYLVAAEHAGIRPLLLLNKADLIDEQNAPALNALLAVYRTLGYPVLEVSAHHGDGMQSLQSQLDGHISVFVGQSGVGKSSLVNSLLPETDTRVGPLSEVSGQGTHTTTTARLFHFPRGGDLIDSPGIREFGLGHVSRADVEAGFIEFNDLIGTCRFRDCKHDREPGCALLKGLEDGRVQQQRMNSYRSIIASLPQDSY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_ENTFA
Sequence: MPNVALFKQDGTQNGEITLNEEIFGIEPNESVVYDAIIMQRASLRQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKFPKKVRRLAMKSVLSDKVAENNLVAVEGLSFDAPKTKEFKQVLANLSIDTKVLVVLENGNDFAALSARNLPNVSVVTSDNVSVLDVVSANKVLATQTALTQIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y1868_DICDI
Sequence: MLLDVINFNVANGPGKSDIIQCFIFLQLIQSLERMKYLNSEKKRIILMFPRNNDPKVTK
What are the official names of this protein?
Putative uncharacterized protein DDB_G0293310.
Protein: PDUO_MYCTU
Sequence: MAVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPGGDRTAS
What are the official names of this protein?
Corrinoid adenosyltransferase, Cob(II)alamin adenosyltransferase, Cob(II)yrinic acid a,c-diamide adenosyltransferase, Cobinamide/cobalamin adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Cob(I)alamin adenosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y910_MYCTO
Sequence: MAKLSGSIDVPLPPEEAWMHASDLTRYREWLTIHKVWRSKLPEVLEKGTVVESYVEVKGMPNRIKWTIVRYKPPEGMTLNGDGVGGVKVKLIAKVAPKEHGSVVSFDVHLGGPALLGPIGMIVAAALRADIRESLQNFVTVFAG
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Its toxic effect is neutralized by coexpression with cognate antitoxin MT0933 (By similarity).
What are the official names of this protein?
Toxin MT0934.
Protein: YFJR_BACSU
Sequence: MKIAVIGLGNMGQPIARNVLQAGYELTVYNRTKQKTEDLVTEGAQAADTPRLAAKSADIVITMLADDDSVSTVTFGEDGLLEGLAENGIHISMSTISVEFSEKLAAAHAEKGQFFLAAPVLGRPDAAAKAALRIITAGPAEAKQAAKPLLDSLSQQIFDVGEESKTANAAKISINFLLVSMLEALSESFLMMEKYGLEQKQFLEIASALFGSPVYQNYGTIMAEQKFEPAGFKMSLGLKDTNLALAAAKRVSANLPLAELAKSHFESGIEKGFGDLDWAALIKCIK
What are the official names of this protein?
Uncharacterized oxidoreductase YfjR.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family.
Protein: IXTPA_MYCTU
Sequence: MALVTKLLVASRNRKKLAELRRVLDGAGLSGLTLLSLGDVSPLPETPETGVTFEDNALAKARDAFSATGLASVADDSGLEVAALGGMPGVLSARWSGRYGDDAANTALLLAQLCDVPDERRGAAFVSACALVSGSGEVVVRGEWPGTIAREPRGDGGFGYDPVFVPYGDDRTAAQLSPAEKDAVSHRGRALALLLPALRSLATG
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: METK_HALMA
Sequence: MTERNIHVQPASGLAVEDQDIEVVERKGIGHPDTICDGIAETVSRALAQTYIDRFGTVLHYNTDETQLVAGTAAPAYGGGEVLEPIYILVVGRATKKFDGERIPAESIALRAARDYLDEQFPHLDLGSDVIVDVQFGEGSGDLQTVFGEEAAIPMANDTSYGVGHAPLTETEQIVRNTEQKLTGEYAESNPVVGQDVKVMGKREGDHIDVTVAVAMVDEHVPDLDAYKTAVSDVRAFVTDLAEEYTDRDVTVHVNTADDYDAESIYLTTTGTSAEQGDDGSVGRGNRANGLITPNRPMSMEATSGKNPVNHIGKIYNLLSTEIAQSVANEVDGIRQVQMRLLSQIGSPIDEPHVADATVVTEDGVAVGDVEADIQATIDDELADVTDITRQVIEGDLSTF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: RLMI_SHEB5
Sequence: MAIRIKLKPGREKSLERRHPWVFSNAIHNIKGKPEAGETVDVVAHDGHWLGRGAWSPESQIQVRIWTFDREEEIDREFFARRLQRAQIGRNDLIREQGLTGYRLVAAESDGLPGITIDRYANVLVCQLLSTGADLWRDTLVELLAEQYPDCAIYERSDVDSRKKEGLLPVTGLLHGTLPEMPVIIEENGIKIAVDVIKGHKTGFYLDQRDNRAIAARFVKDKSVLNCFCYTGTFGLYAAKAGAASIENVDVSSLALATARLNMQVNGLSDDNVHYNEADVFKLLRLYRDEGKTFDVIVLDPPKFADNKAQLNGACRGYKDINMIALQLLNPGGVLLTFSCSGLMPADLFQKIVADAALDAKREIQFIERLSQASDHPIGSAFPEGFYLKGLVARAW
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLX1_ASPCL
Sequence: MENIQLEHSKPIPAFYCCYLLRSTVRHASLYIGSTPNPARRLTQHNGVVKGGARRTAAEKLRPWEMVMIVEGFMSRLGALQFEWAWQNPGYSRHLRSEEEGLEAPGTTSTTKPKTTRRAKSQTPQPLEFERDPSVSKSLGTPKRKNQRRRRPQRSLTTHFADLHRLLQSPYFSNWPLRIRFFSADVYQSWKAWYDRVDIFLPGHVNILLDGSCPENSAQCSAVGARFGSVEQAKVNYDIIQDYLEKAMFLLDDPKDLSCRVCQTQIAPKEQLAVVCPQAGCHCTCHLLCLSKKFLDAMPEPDCLIPRHGACPACKATVQWSLMMQELSFRSRGEQEALAILKRKRRLDRRQQVISKAKCAGKGVDSSDVRPTSVDLDRSNNNASDDLLLDDDWFDEFASESDSDTGHRSKALSKAAPNLETVVEDSEGDDLEFL
What is the function of this protein?
Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS4_CUPPJ
Sequence: MLLIPAIDLKDGQCVRLKQGDMDQATVFSEDPAAMARHWVNQGARRLHLVDLNGAFVGKPRNEAAIKAIIAEVGDEIPVQLGGGIRDLNTIERWLDDGLSYVIIGTAAVKNPGFLKDACSAFGGHIIVGLDAKDGKVATDGWSKLTGHEVADLARKYEDYGVEAIIYTDIGRDGMLQGINIDATVKLAQSMSIPVIASGGLSNLADIDNLCAVENEGVEGVICGRAIYSGDLNFTDAQARADKLSNGE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF2A_CAEEL
Sequence: MGDNLVYAVRSSEGFYLKRGLGKDAVTVFEQNKTSRDVACNVFAYSNNGQLFAYCDNQVTRVFEIATNKEILCVELKRTRKILFSPKDNFLLTFEPWAVYGPKTAENQKPEPNVRVYSLADGKHVSTFSAPKEASWEPQFSDDESLAARMVGSEVFFYTNMSFDRYDHKLVEKGATNFALSPGPAPNHVAVYVPAVGSTPARVRVHRVSESFPVVGNRTFFKSDKAVMTWNQRGQSLLILASVEVDKTNQSYYGEQSLYLINIQSGESVVVPLEKKGPIYAAKWNPNGREFAVCYGYMPAKVTFYNPRGVPIFDTIEGPRNDVFYNAFGNIVLICGFGNIAKGKMEFWDVETKKEIISIEVPNTTLFDWAPDGQHFVTCTTAPRLRIDNSYRFWHYTGRMLAETHFESPKELWEVRWRPMTGYNKFAIKELTKTDKMAAGLPIRKKDASHPLNNVPAGAVRQAGAYIPPHLRKPLGGGGSAGPPSAAAPTPGNQNQRPAQPRANGNGNAPQPFRPQQSEQERKAFQLKKKVEEIKVLKQRVANGDQLQPNQMEKIQRENEYLSELSKLTI
What is the function of this protein?
Functions in the early steps of protein synthesis of a small number of specific mRNAs.  Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits.  In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
What are the official names of this protein?
Eukaryotic translation initiation factor 2A, eIF-2A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EIF2A family.
Protein: MED2_KLULA
Sequence: MVPKTGVSDRQENKLTQYFDDILRLSADLLTQQQLKTIKLDPKVTTGFSKAQQKGLGDRITQFYSLLDTLDVSLQTTADYVGAVKDSALQLKKQREEEQIKKQEQEKLERQLLEQQKLEQQQLEQKQLKQKQQQQQQQQQQQQQQQPQEQQHEQQQRYSAKNTPIDMLTNFDTDLPSAGITQAQSFNSEFGDLNGMDLSMFDSMDNQVGFGGLQNTSGGNEKKNDPQINFNDTNAPPSAVNVPENGNPSSYLTLNDFNDLGIDWNAANDNNELNLEDFNI
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 2, Mediator complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYL_BACP2
Sequence: MSFQHREIEKKWQDYWLTHKTFATSDSEDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTEENINNFRRQIQSLGFSYDWDREINTTDPNYYKWTQWIFLKLYEKGLAYIDEVPVNWCPALGTVLANEEVIDGKSERGGHPVERRPMKQWMLKITAYADRLLEDLEDIDWPESIKDMQRNWIGRSEGAHVHFEIEGHDEQFTVFTTRPDTLFGATYAVLAPEHALVEKITTATQKEAVEAYIKEIQSKSDLERTDLAKTKTGIFTGAYAVNPLNGEKMPIWIADYVLATYGTGAIMAVPAHDERDYEFAKTFDLPIKAVVEGGDIEEEAYTGDGKHINSDFLDGLGKEEAIEKVIAWLEEHQKGEKKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSSAVSEEDLPLILPKTTEIKPSGTGESPLANIKDWVEVVDPVTGKKGRRETNTMPQWAGSCWYFLRYIDPHNSEELASPEKLKKWLPVDVYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFMKLFNQGMILGENNEKMSKSKGNVVNPDDIVESHGADTLRLYEMFMGPLDASIAWSETGLDGARRFLDRVWRLFTNEDGTISDKVTEQTGGALERSYHETVMKVTDHYEGLRFNTGISQLMVFINDAYKADTLPKEYAEGFVKLLSPIAPHLAEELWNKLGHEGSISYEAWPQYDESKLVDDEVEIVVQLNGKVKAKLTVPADATKEQLEDLAKSDARVKEQLEGKTIRKVIAVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECG_PYRCJ
Sequence: MARRRKYEGLNPFVAAGLIKFSEEGELEKIKLSPKAAIAISLAIIAAILALNLLLPPP
What is the function of this protein?
Involved in protein export.  The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
What are the official names of this protein?
Preprotein translocase subunit SecG, Protein transport protein Sec61 subunit beta homolog.
What is the protein family that this protein belongs to?
Belongs to the SEC61-beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: LAC22_ORYSJ
Sequence: MAVLPESRRLSLLLMAACFLLQALSAHAITRHYKFNVVMRNMTRLCSTKPILTVNGKFPGPTLYAREGDNVLVKVVNHVAHNVTIHWHGVRQIRTGWYDGPAYITQCPIQPGSSFLYNFTITGQRGTLLWHAHINWLRATVHGAIVILPKLGVPYPFPAPHKEAVIVLGEWWKEDTETVINQAMQLGVGPNISDSHTINGHPGPLSECASSQDGFKLSVENGKTYMLRIINAALNDDLFFKVAGHELTVVEVDAVYTKPFKTDTLLITPGQTTNVLVRANQGAGRYLLSVSPFMDAPVQVDNKTGTATLHYANTVSSSMASLTLVKPPPQNATHIVSKFTDSLHSLNSKEYPANVPQTVDHSLLLTVGVGVNPCPSCINGTRVVGTINNVTFIMPSTPILQAHYYNIPGVFTEDFPATPLHKFNYTGSGPKNLQTMNGTRVYRLPYNASVQVVLQDTGIISPESHPIHLHGFNFFVVGKGVGNYNPRTSPSTFNLIDPIERNTIGVPTGGWTAIRFRSDNPGVWFMHCHFEVHTSWGLKMAFVVDNGKRPSETLIPPPKDLPQC
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-22, Benzenediol:oxygen oxidoreductase 22, Diphenol oxidase 22, Urishiol oxidase 22.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.