PharMolix/UniProtQA huggingface dataset:
Protein: S2529_RAT
Sequence: MALDFLAGCAGGVAGVIVGHPFDTVKVRLQVQNTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGQDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQAAGPARAYKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVLTRAMGCEPGDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPRYRGIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATFATVTVVLTYIRGEEDQVDSEAAPGASTTPAGPALAQPSSL
What is the function of this protein?
Mitochondrial transporter of arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine.  Does not transport carnitine nor acylcarnitines.  Functions by both counter-exchange and uniport mechanisms.  Plays a physiolocical role in the import of basic amino acids into mitochondria for mitochondrial protein synthesis and amino acid degradation.
What are the official names of this protein?
Mitochondrial basic amino acids transporter, Carnitine/acylcarnitine translocase-like, CACT-like, Mitochondrial carnitine/acylcarnitine carrier protein CACL, Mitochondrial ornithine transporter 3, Solute carrier family 25 member 29.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: SYDND_METSB
Sequence: MHRYRSHTCGDLRETDALQPTRLSGWCHRIRDHGGVLFIDLRDHYGITQCVVDPDSGAFPLAEKLRSEWVVRIDGLVRQRPAGTENIEMPTGLIEVYVTEIEVLGAAAELPLPVFGDQNYPEDMRLRYRFLDLRREKLHNNIMLRGRVIDSLRARMKGQGFFEFQTPILTASSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMTAGFDRYFQIAPCFRDEDLRADRSLEFYQLDIEMSFVTQEDIFATVEPVLRGVFEEFGEGFAVTPEFPRIPYAETMLKYGTDKPDLRNPLVIVDVTEEFSREDVSFNAFKNVIKQGGVVRAIPAPGAGAQPRSFFDKLNDWARGEGAAGLGYVIFEGDAGALVGKGPIAKFLPADVQQAIAAKAGLKSGDAVFFACDRPDRAAKLAGAARLRIGSELKLSKTGVFELCWIVDFPMYEWNEDEKRIDFSHNPFSMPNCNLEQFLALETGVREEIVGIDRGERNRDLNESNELRKRILEITAFQYDVVCNGFELSSGAIRNHRPDIMRKAFALAGYDETVLEQKFGGMYRAFHYGAPPHGGIAPGVDRIVMLLAGEENLREIVAFPMNQRGEDLLLGAPSNVTAKQLRELSIKLNLPEK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_PHOPR
Sequence: MKFIVKPHPEIFCKSDSVRKRFIKILDSNIRIMVKRVSESVAVYNRRYHIEVTANDDSDRDQILAILMQTPGIHHTLEVKQTEFKDLHDIFEQTLELVGEQLEGKTFCVRAKRRGQHDFTSIELERYVGGGLNQAVESASVKLKNPDITVRIEVDYDHLHQVLHRHKGLGGFPLGTQEDVLSLISGGFDSGVSSYLHIKRGSKVHYCFFNLGGPAHEIGVKQVSHFLWKKYGSSAKVKFISIDFEPVVAEILEKVDNGQMGVVLKRMFMRAAGQVAERYGIQALVTGEALGQVSSQTLTNLRMIDNVTDSLILRPLINWDKEDIIDIARNIGTEEFAKTMPEFCGVISKNPTIKAVKAKLEKEEANFDFAILDRVIEEARVMDIRDIEKQSQEQAPEIELVDQIGDGAIVLDIRSPDEEDESPLVIDGVEVKHLPFYKLATQFGDLDQDKEYLLYCDRGVMSRLQALYLTENGYGNIKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHR_LEMCA
Sequence: MPVQGSQRSLLGAVNSTPTATPHLRPAANQTGPQCLEVSIPDGLFLCLGLVSLVENTLVVAAIAKNRNLHSPMYCFICCLALSDLLVSVSSVLETAVLLLLGAGALAAQATVVQQLGNVIDVLLCSSMVSSLFFLGAIAMDRYISIFYALRYHSIVTLARARRAIAAIWAASILSSTLFIAYCDRTAALLCLVVFFLAMLVLMAVLYVHMLTQARQHAQGIARLHKRQRPVQQGWGLKGAATLTILLGVFFLCWGPFFLHLTLIAVCPQHPTCSCIFKNFRLFLALIVCNAIVDPLIYAFRSQELRKTLKEVLLFFW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SNURF_RAT
Sequence: MERGRDRLHLRRTTEQHVPEIEVQVKRRRTASLSNQECHLYPRRSQQQQIPVVDFQAELRQAFLAETPRGG
What are the official names of this protein?
SNRPN upstream reading frame protein.
What is the protein family that this protein belongs to?
Belongs to the SNURF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: REG3_PYRFU
Sequence: MLDELDKRILYFLQEDGRRSYSEIARILGVPESTVRVRVKKMLKNGIIRKFAALINPFKAGYEIVAVIAVDVEPNKVREVAEKLAELNEVDVLGIATGAHDIFMQVTVKSLRELEEFLLDKLGKIEGIKSTETSILTSVKKWGYARVF
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator PF1231.
Protein: RNPH_SYNAS
Sequence: MRKNRRHEDELREVKITRNYLKHPQGSVLIEVGDTKVICTAALEAKVPPFLRNSGKGWLTAEYAMLPMATQERNQRESVRGHIGGRTHEIQRLIGRSLRAVTDLDSLGENTVYIDCDVIQADGGTRTASITGSFVALVDLFRKMKEKGICETMPIRDYVSAVSVGVVDGQLLLDLEYEEDSRADVDMNVVMTGAGEFIEVQGTAERVPFGRDRLTAMVELAGRGIRKLTEVQREILGGQI
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ARLY_MAGMM
Sequence: MSDGKPMGKLWGGRFSEPTNAFVEAFSASIDYDARLYRHDIRGSIAHCAMLGRQGIIPQADAERIIQGLQQVRGEIDRGEMHYSNALEDIHMHVESRLTEIIGPVAGKLHTARSRNDQVATDFRLYLRDELDAIVQAIRTLQGGLVMLAEQHAHVIMPGFTHMQSAQPVTFGHHMMAYYEMLKRDYGRFSDMRPRLNRMPLGSAALAGTTFPLDRESVARELEFDGLCENSLDAVSDRDFAIEMMAACATLMMHLSRFSEELILWSAPAYRFIRLPDAFCTGSSIMPQKKNPDVPELVRGKVGRVYGALTSVLTLMKGLPLAYNRDMQEDKEAVFDAVDTVRACLRVFGDMVPGIQPQVATLRGAAGAGFATATDLADYLVRKQIPFREAHEIVGTIVRMAEQQGVDLDGLTLADLQSVDGRIESDVTAILSVESSVNARQAIGGTAVATVRTAIAMAKQELAL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_PSEPG
Sequence: MAKQKKHPTGTIAQNKKARHDYFIEHKFEAGLVLSGWEVKSLRAGKAHLTDSYVLLKDGEAWLFGSHITPLTTASTHVIADPIRTRKLLLNKRELERLEAAVAQKGYTCVALALYWSKHLIKCEIALGKGKKEFDKRDTMRERDSNRELQRAVRNKGKED
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: 4HPE1_BURM1
Sequence: MMKRIQIIDSHTGGEPTRLVVSGFPSLGSGTMAERRDVLAREYDRYRTACILEPRGSDVLVGALLCEPVSPDAAAGVIFFNNSGYLGMCGHGTIGVVRTLHHMGRIGPGVHRIETPVGTVEATLHDDLSVSVRNVLAYRHAKDVALDVPGYGPVRGDIAWGGNWFFLISDHGQRVAGDNVAALTAYASAVREGLERAGITGANGGEIDHIELFADDPEHDSRSFVLCPGLAYDRSPCGTGTSAKLACLAADGKLAPGAVWRQASVIGSVFHASYVQAEGGIVPTIRGSAHLSAEATLLIEDDDPFRWGIVS
What is the function of this protein?
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp).  Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate.  Displays no proline racemase activity.
What are the official names of this protein?
4-hydroxyproline 2-epimerase 1, 4Hyp 2-epimerase 1, 4HypE 1.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: ENLYS_BPMD2
Sequence: MTLIVTRDHAQWVHDMCRARAGNRYGYGGAFTLNPRDTTDCSGLVLQTAAWYGGRKDWIGNRYGSTESFRLDHKIVYDLGFRRLPPGGVAALGFTPVMLVGLQHGGGGRYSHTACTLMTMDIPGGPVKVSQRGVDWESRGEVNGVGVFLYDGARAWNDPLFHDFWYLDAKLEDGPTQSVDAAEILARATGLAYNRAVALLPAVRDGLIQADCTNPNRIAMWLAQIGHESDDFKATAEYASGDAYDTRTDLGNTPEVDGDGRLYKGRSWIMITGKDNYRDFSRWAHGRGLVPTPDYFVVHPLELSELRWAGIGAAWYWTVERPDINALSDRRDLETVTRRINGGLTNLDDRRRRYNLALAVGDQLLTLIGDDDELADPTIQRFIREIHGALFNTVVTQSPYGDPQNPDGSEPRSNLWQLHELIKNGDGMGHARYVEESARAGDLRELERVVRAAKGLGRDRSPEFIARARNVLAQIEAANPEYLQAYIARNGAL
What is the function of this protein?
Endolysin that degrades host peptidoglycans and participates with the holin protein in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles.  Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.
What are the official names of this protein?
Endolysin A, Gene 10 protein, Gp10, Lysis protein, Lysozyme.
What is the protein family that this protein belongs to?
Belongs to the L5likevirus endolysin A protein family.
Protein: UPP_HELMI
Sequence: MARVVIMDHPLIQHKLSFIRSKNTGSKEFRELVEEVAMLMAYEVTRELPLVETEVETPVAVAKTKVLAGKKLGVVAILRAGLGMINGFVKLIPAAKVGHVGLYRDPKTLEPVEYYCKLPPDVAERDMIVIDPMLATGGSASAALTLLKQKGARHIKLVVLIAAPEGVSRVEQDHPDVDIYAAALDPCLNDHAYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: Y333_STRZJ
Sequence: MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHAARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKFNELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKSMLERILGKSPYASPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVSEAAVKKIELLMNDLGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKSADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEELGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK
What are the official names of this protein?
UPF0371 protein SPJ_0333.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: LOLD_BRADU
Sequence: MEQQQGAEDVPVIYLHEIKRQYLQGEVPLTILDGAKLALWAGQSVALVAPSGSGKSTLLHIAGLLEAPDSGEVYVNGAPTSQLPDIERTQLRRTDIGFVYQSHRLLPEFSALENVMLPQMIRGLKKSESVKRAKEILGYLGLGDRITHRPAELSGGEQQRVAIARAVANAPRVLFADEPTGNLDPHTADHVFQALMQLVKATRVSMLIATHNMELAGRMDRRVSLSDGQVVELE
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ASNS_CRIGR
Sequence: MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVKKYPYLWLCYNGEIYNHKALQQRFEFEYQTNVDGEIILHLYDKGGIEQTICMLDGVFAFILLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVSLKHSTTPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCRDEPLHALYDSVEKLFQGFELETVKSNLRILFDSAVRKRLMTDRRIGCLLSGGLDSSLVAASLLKQLKEAQVQYPLQTFAIGMEDSPDLLAARKVANYIGSEHHEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVVIFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLKELYLFDVLRADRTTAAHGLELRVPFLDHRFSSYYLSLPPEMRIPKNGIEKHLLRETFEDSNLLPKEILWRPKEAFSDGITSVKNSWFKILQDYVEHQVDDEMMATAAQKFPFNTPKTKEGYYYRQIFERHYPGRADWLTHYWMPKWINATDPSARTLTHYKSAAKA
What are the official names of this protein?
Asparagine synthetase [glutamine-hydrolyzing], Glutamine-dependent asparagine synthetase.
Protein: RS2_RALPJ
Sequence: MSVTMREMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMYQDALKYVRQLAANRGTILFVGTKRQSREILAEEAARAGMPFVDSRWLGGMLTNFKTVKTSIKRLKDMEVAKEAGATETMSKKEALMFEREMDKLVKSIGGIKDMGGIPDAIFVVDVGYHKIAVTEAAKLGIPVIGVVDTNHSPEGIDYVIPGNDDSSKAVALYVRGVADAILEGRANAVQEVVEAARGGDDFVEVQEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: Y2495_CROS5
Sequence: MTYHLRIADIPSSERPRERLMAVGAKNLATAELLAILLGTGQGKGKLSAVGLGHHILQELSKHRRDPLDILRDISPHELMSIDGIGPAKATTIIAAVELGKRTFQVRPLERVTIDSPEAAVAALSHDLMWERREHFAAVFLDSKYRLLGTKVITIGTATETLVDPAEIFRETLKQGANALIVAHNHPSGNVEPSQQDLDLTEQLLKGMQLIRIPLIDHLILGEGNHCSLHRATDLWQRYPQE
What are the official names of this protein?
UPF0758 protein cce_2495.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: DBH1_STRCO
Sequence: MNRSELVAALADRAEVTRKDADAVLAAFAEVVGDIVSKGDEKVTIPGFLTFERTHRAARTARNPQTGEPIQIPAGYSVKVSAGSKLKEAAKGK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU 1, HSl.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RS17_VIBC1
Sequence: MSEVKRTQQGRVVSDKMDKSIVVAIERMVKHPIYGKFVKRTTKVHAHDENNECGLGDTVEIAECRPLSKTKSWTLVKVLEKAKI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PABP4_ARATH
Sequence: MAQVQAPSSHSPPPPAVVNDGAATASATPGIGVGGGGDGVTHGALCSLYVGDLDFNVTDSQLYDYFTEVCQVVSVRVCRDAATNTSLGYGYVNYSNTDDAEKAMQKLNYSYLNGKMIRITYSSRDSSARRSGVGNLFVKNLDKSVDNKTLHEAFSGCGTIVSCKVATDHMGQSRGYGFVQFDTEDSAKNAIEKLNGKVLNDKQIFVGPFLRKEERESAADKMKFTNVYVKNLSEATTDDELKTTFGQYGSISSAVVMRDGDGKSRCFGFVNFENPEDAARAVEALNGKKFDDKEWYVGKAQKKSERELELSRRYEQGSSDGGNKFDGLNLYVKNLDDTVTDEKLRELFAEFGTITSCKVMRDPSGTSKGSGFVAFSAASEASRVLNEMNGKMVGGKPLYVALAQRKEERRAKLQAQFSQMRPAFIPGVGPRMPIFTGGAPGLGQQIFYGQGPPPIIPHQPGFGYQPQLVPGMRPAFFGGPMMQPGQQGPRPGGRRSGDGPMRHQHQQPMPYMQPQMMPRGRGYRYPSGGRNMPDGPMPGGMVPVAYDMNVMPYSQPMSAGQLATSLANATPAQQRTLLGESLYPLVDQIESEHAAKVTGMLLEMDQTEVLHLLESPEALNAKVSEALDVLRNVNQPSSQGSEGNKSGSPSDLLASLSINDHL
What is the function of this protein?
Binds the poly(A) tail of mRNA.  Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (By similarity).  During infection with potyvirus TuMV, acts as a potential integral component of the viral replicase complex that could play an important role in the regulation of potyviral RNA-dependent RNA polymerase (RdRp) (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein 4, PABP-4, Poly(A)-binding protein 4.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FADB_SHEON
Sequence: MIYQSPTIQVELLEDNIAKLCFNAPGSVNKFDRETLASLDAALDSIKQQSNIQALVLTSGKDTFIVGADITEFLGLFAQDDAVLLSWVEQANAVFNKLEDLPFPTASAIKGFALGGGCETILATDFRIADTTAKIGLPETKLGIIPGFGGTVRLPRVIGADNALEWITTGNEQRAEDALKVGAVDAVVAPEALEVAAIQMLKDAVAEKLDWQARRQRKLSPLTLPKLEAMMSFTTAKGMVFSVAGKHYPAPMAAVNVVEQAATKGRSDALQIEHQAFIKLAKTDVAKALIGIFLNDQFVKGKAKKAGKLAKAVNSAAVLGAGIMGGGIAYQSASKGTPIVMKDIAQPALDLGLNEAAKLLSAQVARGRSTPEKMAKVLNNITPALEYAPVKHADVVVEAVVEHPKVKAQVLAEVEQYVSEDAIIASNTSTISISLLAKSMKKPERFCGMHFFNPVHKMPLVEVIRGEHSSEETIASVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFNGLLAEGGDFAAIDKVMEKQFGWPMGPAYLLDVVGLDTGHHAQAVMAEGFPDRMGKSGNDAIDVMFENKRLGQKNGKGFYAYSVDSRGKPKKDVDPTSYELLKAAFGEQKAFDADEIIARTMIPMIIETVRCLEEGIVASPAEADMGLVYGLGFPPFRGGVFRYLDTMGVANFVALADKYAHLGGLYQVTDAMRALAANNGSYYQA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: THI4_UROFA
Sequence: MSPVATESMYKPTTINQTAHQQAMDPLKSKQQSNATVNKPAFKPEPAVNLTPIKFAPIKEHQVQRAMVRRYFQDMEERAISDVIIVGAGSAGLSCAYALGTARPDLKITILESNVAPGGGCWLGGQLMSAMVCRKPADEFLDQVGVPYEDEGNFVVVKHAALFTSTVLSKVLAMPNVKMFNATACEDLIIKPCPINPGVQRIAGCVTNWTLVSLNHDHQSCMDPSTITAPLVCSFAGHDGPFGAFCVKRVASAGLSEGLGDMRPLDMERAEDHIANKTREILPGLIVGGMELSEFDGSARMGPTFGAMLLSGKRAAEVALQSLDRVKIEEGEVVGLAK
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, Planta-induced protein 4, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATP6_PROM4
Sequence: MGSFPFLLPFAELEVGQHLYWQLGNIRIHGQVFMTSWLLIGALLTLVVVGTKKMERDPKGVQNLLEFLWDYIRDLARTQIGEKVYRDWMPFIGTLFLFIFVSNWGGALVPWRLIRLPSGELGAPTADINTTVALALLVSLSYFYAGLSNKGLRYFEYYVHPTPIMLPFKIVEDFTKPLSLSFRLFGNILADELVVAVLVFLVPLVLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: ISPG_PSEU2
Sequence: MHGESPIKRRESRKIWVGSVPVGGDAPIAVQSMTNSDTNDVAATVAQINRLEAAGVDIVRVSVPDMDAAEAFGRIKQLVKVPLVADIHFDHRIALRVAELGVDCLRINPGNIGREDRVRAVVDAARDRGIPIRIGVNAGSLEKDLQKKYGEPTPEALVESALRHVEHLQRLNFQDFKVSVKASDVFMAVAAYRLLAKEIVQPLHLGITEAGGLRSGTVKSAVGLGMLLAEGIGDTIRISLAADPVEEVKVGYDILKSLRLRSRGINFIACPSCSRQNFDVVKTMNELEGRLEDLLVPLDVAVIGCVVNGPGEAKEAHIGLTGGTPNLIYIDGKPAQKLTNDNLVNELERLIREKAAEKAEADASVIVRG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: KDSB_NEIG1
Sequence: MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTACQAHGIEVVMTSNRHESGTTRLAEAAAALKLPPHLIVVNVQGDEPLIAPELIDRTAEVLVENNVQMATAGHELHDFDELMNPNAVKVVLDKNGNAIYFSRAPIPYPRDAMRAGKREMPSETAVLRHIGIYAYRVGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQEDLDRVRAVFQTV
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_SHESH
Sequence: MTELKQSIQPIGIFFNAQYPSLEAICQRWGLVFDKEAAFELVFENNCLVLNKRDEPKLKGISVDFVSGAVAHRRKFGGGRGQSIAKAVGLKQGVNPSVVDGTAGLGRDAFVLASLGCNVTMVERNPVVAALLEDGLRRAYESEEIGDWMRERMRLVHGSSLESVAELGEEIDVVYLDPMYPHREKSALVKKEMRVFQSLVGADLDADGLLAPATALATKRVVVKRPDYAEDLDGVKPSMVISTKKNRFDVYVKAAMKA
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7A_HALSA
Sequence: MPVYVDYDVPADLQERALESLEVARDTGSVKKGTNETTKAIERGNADIVFVAEDVSPEEIVMHLPELAAEKGIEVVFVETQDELGNAAGLEVGSAAAAVVAAGDAEDEIEDISTKVEDLQ
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BACAH
Sequence: MPRVKGGTVTRQRRKKVIKLAKGYYGSKNTLFKVANQQVMKSLMYAFRDRRQKKRDFRKLWITRINAAARMNGLSYSRLMHGLKNAGIEVNRKMLADLAVHDEKAFAELATVAKNNIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RM01_HUMAN
Sequence: MAAAVRCMGRALIHHQRHSLSKMVYQTSLCSCSVNIRVPNRHFAAATKSAKKTKKGAKEKTPDEKKDEIEKIKAYPYMEGEPEDDVYLKRLYPRQIYEVEKAVHLLKKFQILDFTSPKQSVYLDLTLDMALGKKKNVEPFTSVLSLPYPFASEINKVAVFTENASEVKIAEENGAAFAGGTSLIQKIWDDEIVADFYVAVPEIMPELNRLRKKLNKKYPKLSRNSIGRDIPKMLELFKNGHEIKVDEERENFLQTKIATLDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRAFLRSSTSEGLLLKIDPLLPKEVKNEESEKEDA
What are the official names of this protein?
39S ribosomal protein L1, mitochondrial, L1mt, MRP-L1, Mitochondrial large ribosomal subunit protein uL1m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Mitochondrion.