PharMolix/UniProtQA huggingface dataset:
Protein: RNR_VIBCH
Sequence: MSDTTHLDPFADREADNYDNPIPSREYILEFLTQANVPMNRNDLFEALKLEGEEQYEGLRRRLRAMERDGQLVFTRRQCYALPEKLEMVKGYVIGHKDGHGWVRPEGSLNKEGDILLPHHQMRTLIHGDFVLVQPSGTDKRGRKEGRLVRILEERNGQIVGRFFFEYGYSYVVPDDSRIHHDILIPNDLRAGARMGNVVVIEITDRGTRNRGMMGKVVEVLGENMAPGMETQIAIRTHQIPHEWPAEVEQQVAGLTEEVPEEAKQGRVDLRALPLVTIDGEDARDFDDAVYCEAKKGGGWRLWVAIADVSYYVRPDTALDKEAINRGNSVYFPSQVVPMLPEVLSNGLCSLNPQVDRLCMVCEMTVSETGKLSGYKHYEAVMNSHARLTYTKVHEILEGDEELRERYKALVPHLEELHKMYQVLKSARDERGAIEFETVETKFIFNAQRKIESIEPVVRNDAHKLIEECMILANIASASLVEKAKEAALYRVHEPPGEERLTGFRDFLGELGLDLSGGLEPSPTDYANLMKQIGERPDKELIQTMLLRSMKQAVYNADNAGHFGLALKRYAHFTSPIRRYPDLLLHRAIKYLIAKQEGRNQDRWTPTGGYHYSFDDMDFYGEQCSMTERRADDATREVSDWLKCEYMQDHVGEELEGVVANVTSFGFFVRLTELHIDGLVHISTLANDYYHYDPIGQRLVGESFGAIYRLGDAVKVKVLAVNLDDRQIDFELVETSRKLRGQGKTAKKRADEARAKAQGKKEAATKGACGKSPTKSELKPQVEATRRPDSEGRSKPKKTKAPKKRKDQARKKSGKVRDKTK
What is the function of this protein?
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
What are the official names of this protein?
Ribonuclease R, RNase R.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase R subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAHE1_PSEPU
Sequence: MLNKVIKTTRLTAEDINGAWTIMPTPSTPDASDWRSTNTVDLDETARIVEELIAAGVNGILSMGTFGECATLTWEEKRDYVSTVVETIRGRVPYFCGTTALNTREVIRQTRELIDIGANGTMLGVPMWVKMDLPTAVQFYRDVAGAVPEAAIAIYANPEAFKFDFPRPFWAEMSKIPQVVTAKYLGIGMLDLDLKLAPNIRFLPHEDDYYAAARINPERITAFWSSGAMCGPATAIMLRDEVERAKSTGDWIKAKAISDDMRAADSTLFPRGDFSEFSKYNIGLEKARMDAAGWLKAGPCRPPYNLVPEDYLVGAQKSGKAWAALHAKYSK
What is the function of this protein?
Involved in the naphthalene upper catabolic pathway.  Catalyzes the transformation of trans-O-hydroxybenzylidenepyruvate (THBPA) to salicylaldehyde and pyruvate.  The reaction is reversible.  Can also use substrate which carry trans-alpha,beta-unsaturated keto acid side chain and adjacent hydroxyl group such as trans-4-(3-hydroxy-2-thianaphthenyl)-2-oxo-but-3-enoate, trans-4-(3-hydroxy-2-benzofuranyl)-2-oxobut-3-enoate, and trans-4-(3-hydroxy-2-thienyl)-2-oxobut-3-enoate.
What are the official names of this protein?
Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase, THBPA hydratase-aldolase, 2'-hydroxybenzalpyruvate aldolase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: PLSX_PHOLL
Sequence: MTNLTLALDAMSGDFGPRVTVPAALQALASNPRLKLLLVGIPDIISPMLVNSDTELLSRLQLVPAERVVANDAKPSQAIRNSRGTSMRIALDLVKSGEAQACISAGNTGVLMGLSKLMLKSIEGIERPALMTVLPNLKQRQTVVLDLGANVNCDSRMLVQFAIMGSVMAEEVVGVVNPAVALLNIGTEESKGLDNIREAATILKRIPTINYIGYLEGDELLTGKSDVLVCDGFAGNVTLKTMEGAIRVILSLLKSSDGQKKKFSWLLRIVKKWLQKRMTKRFGHLNPDQYNGACLLGLYGIVIKSHGAANEHAFKAAIEQAVQAVERQVPDRIAARLETALPKSD
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: IF4AX_DICDI
Sequence: MSEGDLFLISFLKVGFASLGLNEQLINNIKRYGITKLTPFQMEVIKEIKENSNVIVDSIEGTGRTISLIIGTLDKIDETKQQQEQEQQERQQTDQQFSFPQILMILPTKELSQTTKVIYSSLGGGENNNNDFKVLSCIGGVKISMDIEILKKGNTQILLGTPGRISDLFSRKRFDTDNIKILVFDELDEILSRGFECQLEDIIKPLNNNNNLQIIVSTSGINELTSNFINTFIKIPKIIKSQQEPYKF
What are the official names of this protein?
Putative eukaryotic initiation factor 4A-like protein.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: RIMP_KOCRD
Sequence: MSSEHHAPIRATVEPVVAAAGLHLEECELKGQGATRTLQVLVDLPDGTEALGLDRVAAVAQEISDALDRDDPVPGPPYELEVSSPGATRTLETPRHWRRTVGHLVRIRTLEGERYTARLLEAHEDHAVVQRSHQPKKGMPVKLLDPERVDYASIRTARSEVEN
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPXN5_HUMAN
Sequence: MEKPTSSTNGEKRKSPCDSNSKNDEMQETPNRDLVLEPSLKKMKTSEYSTVLVLCYRKTKKIHSNQLENDQS
What are the official names of this protein?
Sperm protein associated with the nucleus on the X chromosome N5, Nuclear-associated protein SPAN-Xn5, SPANX-N5, SPANX family member N5.
What is the protein family that this protein belongs to?
Belongs to the SPAN-X family.
Protein: YUSG_BACSU
Sequence: MAFDKQKLDVTNDVTGRFQNGRLSLYHDNEMIGQMTSMNEYELKSGYSFENEKFYKTADVVSGDDAKYVDCDYENGWC
What are the official names of this protein?
Uncharacterized protein YusG.
Protein: Y6832_DICDI
Sequence: MLILSVFCAVFYAFLTAIVANFSLKTLAIGATFVKSHLKSNPIPYGDLVADSLDFGNITPTVTLLFAILIAVLALKCEFSCSTSAPAGQASGRKVK
What are the official names of this protein?
Uncharacterized transmembrane protein DDB_G0286141.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: KDSB_BRUMB
Sequence: MLQTMKTLTLIPARLGSTRLPNKPLADICGKPMIVHVADRAAAAKLGRTVIATDSEEIFKVVAAHGHEAIMTRGDHESGSDRIYEALAKLDPSGEIDAVVNVQGDLPTIDPDTIRRALLPLEDGPADIATLGVEITVEEEKTNPNVVKIVGSPLAGNRRLRALYFTRATAPYGEGPLYHHIGLYAYRRSALERFVKLGPSPLEKREKLEQLRALEAGMRIDVEIVKTVPLGVDTQADLDRARTFCSQAGTI
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_RHILW
Sequence: MALKTFNPITPSQRQLVIVDRSALYKGKPVKALTEGLTKSGGRNNLGRITARFIGGGHKRTYRLIDFKRRKFDVEGTVERIEYDPNRTAFIALVNYADGEKAYILAPQRLAAGDKVIASEKAVDVKPGNTMPLQFIPVGSIIHNVEMKPGKGGQIARSAGGYAQLVGRDQGMAILRLNSGEQRLVHGSCLASIGAVSNPDHANINDGKAGRTVWRGKRPHNRGVVMNPVDHPHGGGEGRTSGGRHPVTPWGKPTKGKRTRSNKSTDKMIMRSRHQRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: FADI_YERPE
Sequence: MSKPLPLVTRQGDRIVIVNGLRTPFAKQATAYHGVPAVDLGKIVVSELLARSGISSELIDQLVFGQVVQMPEAPNIAREIVLGTGMSVHTDAYSVSRACATSFQAVANVAESIIAGSVDIAIAGGADSSSVLPIGVSKALARTLVDANKARSLSQKLKLFSRLRLRDLLPVAPAVAEYSTGLRMGDTAEQMAKTYGISREDQDALALRSHQLAAEAWQQGWLHDEVMTAYIPPYREAIIEDNNIRKDSTLAQYAKLRPAFDRQHGSVTAANSTPLTDGAAAVLMMSESKAKALGLPPLGYLRSFAFSAIDVWQDMLLGPSYATPLALDRAGITLADLTLIDMHEAFAAQTLANLKMFASDTFAREKLGRSQAIGEVDMSKFNVLGGSIAYGHPFAATGARMITQTLNELRRRGGGLGLTTACAAGGLGAAMILEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOAP3_TITOB
Sequence: FIGMIPGLIGGLISAIK
What is the function of this protein?
Antimicrobial peptide (PubMed:27917162).  Is able to kill Mycobacterium abscessus subsp.  massiliense in a dose-dependent manner (PubMed:31376652).  Has antifungal activity against Candida spp.  and one Cryptococcus neoformans strains with MICs values ranging from 12. 5 to 100 uM (PubMed:27917162).  Shows low cytotoxic activity and low hemolytic activity on human erythrocytes (PubMed:31376652).  Shows anti-inflammatory activities, since it decreases release of pro-inflammatory cytokines, and increases release of anti-inflammatory cytokines (PubMed:31376652).  Acts by blocking the Toll-like receptor 4 (TLR4) (PubMed:31376652).  In addition, decreases the expression of costimulatory molecules such as CD80 and CD86 in LPS-stimulated cells (PubMed:31376652).  In vivo, does not induce immune cell migration (PubMed:31376652).  Helical wheel projections predict an amphipathic peptide with distinct hydrophobic and hydrophilic faces (Probable).
What are the official names of this protein?
Antimicrobial peptide ToAP3.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMG_STACT
Sequence: MGVEWLVEKLQEHDITLNDKQKQQFQTYYELLVEWNEKMNLTSITDEEGVYLKHFYDSITAAFYIDMNQELSICDVGAGAGFPSIPLKIVFPQLKVTIVDSLNKRIQFLNHLADALDLRGVSVVHERAENFGNVRGDNRESYDIVTARAVARLSVLSELCLPLVKTGGHFIAMKSSKGEEELEEARFGIGVFGGRVEAVETFELPGDAGERQMIIIEKRSKTPKKYPRKAGTPNKSPLLK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG86_BPMD2
Sequence: MANNYRYVEAVRDAEGFIIDGDYAAWDCSRCGHEAQRYRGQSDVDCRNCGACYNASGQRLRDDWRGNPSAWDDEVGDLEGFELQHSDY
What are the official names of this protein?
Gene 86 protein, Gp86.
Protein: SERC_PARPJ
Sequence: MRVFNFSAGPAAMPEEVLRQAADEMLDWQGSGMSVMEMSHRGKEFMSIHEEALVDLRDLLEVPASHRILFLQGGGLGENAIVPMNLMGAKPRADFVVTGSWSQKSFKEAQKYGTVHLAASGQTAEGFTRAPARSEWQLSDDPAYVHLCTNETIHGVETFEIPDLGDIPLVADASSHILSRPMDIAKYGVLFGGAQKNIGMAGVTVVIVREDMLDRAQSICPSAFEWKTVAENNSMYNTPPTYAIYIAGLVFKWLKKQGGLAAMEARNVEKSKLLYDAVDTSSFYLNKVERGSRSRMNVPFFLADESRNEDFLAGAKARGMVQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKEFEQRSA
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_SACEN
Sequence: MTAANPASTPNPESAPRSRELFDRALAVTPGGVNSPVRAFHSVGGTPRFMVRGEGTYLWDADDNRYVDLVSSWGPMINGHAHPDVVRAVRQAAAGGLSFGTPGVGEIDLAAEIIDRVGPVEQVRLVNSGTEATMSAVRLARGFTGRRKVVKFAGCYHGHVDALLASAGSGVATLGLPTTPGVTGAQAADTIVLPYNDLDAVRRTFAEYGDEIACVITEAAAGNMGAIAPAPGFNGGLREITSSAGALLVMDEVMTGFRVSAAGWFGIDGVAGDLYTFGKVMSGGLPAAAFGGRADVMERLAPSGPVYQAGTLAGNPVAVAAGLANLRAATPEVYAALDRNAERLGELLGSALSAEGVPHQVAFAGNLVSVFFSEDPVRDYAGAQAQQSWRFPPFFHALLERGIYPPPSAFEAWFVNAAMDDAAFDAIAEALPHAAKAAAAATEPGAGA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM38A_HUMAN
Sequence: MELLSALSLGELALSFSRVPLFPVFDLSYFIVSILYLKYEPGAVELSRRHPIASWLCAMLHCFGSYILADLLLGEPLIDYFSNNSSILLASAVWYLIFFCPLDLFYKCVCFLPVKLIFVAMKEVVRVRKIAVGIHHAHHHYHHGWFVMIATGWVKGSGVALMSNFEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFIFTLFMVSCKVFLTATHSHSSPFDALEGYICPVLFGSACGGDHHHDNHGGSHSGGGPGAQHSAMPAKSKEELSEGSRKKKAKKAD
What is the function of this protein?
Monovalent cation channel required for maintenance of rapid intracellular calcium release.  May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
What are the official names of this protein?
Trimeric intracellular cation channel type A, TRIC-A, TRICA, Transmembrane protein 38A.
What is the protein family that this protein belongs to?
Belongs to the TMEM38 family.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane.
Protein: LOLA_HAEIE
Sequence: MKKTTLKFAALTLLGLSNLALADAASELQMRLAKVDVLSAEFVQTVTSGSGKNVQQGSGKLQIKRPNLFRMETKTPQETQIISDGKTLWFYDPFVQQVTAQWVKNAVNNTPFVLLTSNDNSHWHQYTVTQQSDTFVLKPTLSTSNIKQFDIRVDANGILRNFSTTEKDGQTNLYVLRNITNQTLSDSLFQFKPEKGVEVDDQRKK
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NOP10_METS3
Sequence: MNMKMNKCPDCKIYTMEDACPQCGGELKVIYPPKFSIEDKYGKYRRILKKEAMNKKDD
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: AGL92_ARATH
Sequence: MRTKTKLVLIPDRHFRRATFRKRNAGIRKKLHELTTLCDIKACAVIYSPFENPTVWPSTEGVQEVISEFMEKPATERSKTMMSHETFLRDQITKEQNKLESLRRENRETQLKHFMFDCVGGKMSEQQYGARDLQDLSLFTDQYLNQLNARKKFLTEYGESSSSVPPLFDVAGANPPVVADQAAVTVPPLFAVAGANLPVVADQAAVTVPPLFAVAGANLPVVADQAAVNVPTGFHNMNVNQNQYEPVQPYVPTGFSDHIQYQNMNFNQNQQEPVHYQALAVAGAGLPMTQNQYEPVHYQSLAVAGGGLPMSQLQYEPVQPYIPTVFSDNVQYQHMNLYQNQQEPVHYQALGVAGAGLPMNQNQYEPVQPYVPTGFSDHFQFENMNLNQNQQEPVQYQAPVDFNHQIQQGNYDMNLNQNMKHAHIPFMDGNYYNYHQPPTVGLTSTGHMPSTTTTTTNNNNNNNV
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Agamous-like MADS-box protein AGL92.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMA_YERPP
Sequence: MTPNILPIESYDHQLAEKSARLKAMMLPFQAPEPEIFRSPADHYRMRAEFRVWHDEDDLYHIMFDQQTKQRIRVEQFPVASRLINRLMDALMTAIRAEPLLRRKLFQIDYLSTLSGKLIASLLYHRQLDEEWQQKALELRDQLRAQGFDLQLIGRAAKTKIMLDHDYIDEVLPVAGREMIYRQVENSFTQPNAAVNIHMLEWALDVTQGATGDLLELYCGNGNFSLALARNFERVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMQGVREFNRLKGIDLGSYNCETIFVDPPRSGLDHETVKLVQAYPRILYISCNPETLCANLEQLQHTHKISRLALFDQFPYTHHMECGVLLEKRH
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: ATPL_CLOBK
Sequence: MDPKAFVSGMAALGAGIAALACIGAGIGTGNATGKAVEGVSRQPEASGKIMSTLVIGSAFSEATAIYGLIIALFLIFKI
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COX2_RHIDA
Sequence: MAHPFQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLLLTTSLTHTSTMDAQEVETIWTILPAIILIMIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLSFDSYMIPTSDLKPGELRLLEVDNRVVLPMEMTIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLLSNRPGLYYGQCSEICGSNHSFMPIVLELVPLKHFEKWSSSMV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CAPSD_TTVV8
Sequence: MAWPWRRRRWRWRRRRPRWRRWRRRRTWRRRPRRAVRRRRVRRRGRGWRRLYRRYRRRRGRRTYKKKPVLTQWQPTVRRRCFIIGYMPLIICGENLTSKNYASHADDFVKDGPFGGGMTTMQFSLRILYDEFLRFLNIWTHSNQDLDLARYHGFKLTLYRHPTVDFIVIIRNSPPFEDTELTGPNTHPGMLMLRHKKILVPSLRTRPSRRHKITVRIGPPKLFEDKWYSQTDICDVILATVYATACDLQYPFGSPLTENYCISFQVLGSAYNNLISNTLNPNEEQQDIKSAIYNNVNAYLTRITESHMANLISKAPPKQVLKSSDGSLQTDHNDTQFGGNPYNTNQFTTTTVNKIIQGAQNYLTTIKTHLQPNNSAINPNTQWHLEYHAGIYSAPFLSAGRLNPEIKGLYTDITYNPMMDKGTGNKIWCDSLTKADMKYTEGRSKYLIENLPLWAAVWGYLDYCTKTSGDAAFHYNYRVTLISPYTSPMLFNPQDPTKGFVPYSLNFGLGKMPGGKGYVPLRMRANWYPYFFHQQKVLEAIGMSGPFTYRSDEKKAVLTSRYKFKFTWGGNPVSHQVVRNPCKGTGGASASRKPRSVQVTDPKYNTPEITTHTWDIRRGWFGKRFIDRVQQQQASPELLADPPKRPRKEIKGLTEADQEAEKDSGLRLRQVQPWMSSQETQSEQESAPEEQTVEQQLRNQLHTQQLLGFQLRSLMYQVQQTHRNSFIHPLLLPRA
What is the function of this protein?
Self assemble to form an icosahedral capsid.
What are the official names of this protein?
Capsid protein.
What is the protein family that this protein belongs to?
Belongs to the anelloviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: LPXD_METEP
Sequence: MSDPVFIAPKGGLTLGSVAEACGVPLPDGADPAQPVTGAAPLETAGPSELAYMDNARYGDALATTRALACLVSPRFAPRVPAGTIALVTRDPYRAYAGLLARLYEEAMRPGSLFAAAGVSPGAHVHPQARLEDGMRIDPGAVVGPGAEIGSGTVLGPNAVIGPNVRIGRDCSIGAGATLTHALVGNRVIVHPGARIGQDGFGFAMGAGGHIKVPQVGRVIIQDDVEIGANTTIDRGASRDTVVGEGTKIDNLVQIAHNVVIGRHCVIVSGVGISGSTTLEDYVVLGGQVGVVGHLRIGMGSQIAGSSNVNRDVPPGSRWGGTPAKPVRTWFREMTTLARLAERGGKDEAEG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: FLIE_ECO57
Sequence: MSAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: UBC2_YEAST
Sequence: MSTPARRRLMRDFKRMKEDAPPGVSASPLPDNVMVWNAMIIGPADTPYEDGTFRLLLEFDEEYPNKPPHVKFLSEMFHPNVYANGEICLDILQNRWTPTYDVASILTSIQSLFNDPNPASPANVEAATLFKDHKSQYVKRVKETVEKSWEDDMDDMDDDDDDDDDDDDDEAD
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  In association with the E3 enzyme BRE1 and LGE1, it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1.  H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation.  In association with the E3 enzyme RAD18, it catalyzes the monoubiquitination of POL30 'Lys-164', involved in postreplication repair of UV-damaged DNA.  The RAD6/UBC2-RAD18 complex is also involved in prevention of spontaneous mutations caused by 7,8-dihydro-8-oxoguanine.  In association with the E3 enzyme UBR1, is involved in N-end rule-dependent protein degradation.  Also involved in sporulation.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 2, E2 ubiquitin-conjugating enzyme 2, Radiation sensitivity protein 6, Ubiquitin carrier protein UBC2, Ubiquitin-protein ligase UBC2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SFT2_SCHPO
Sequence: MEGSFQSRLQSIIQRTGETTAESTNSWYNRLRTSMPWSNDYTEIPTNASGGNSYFQSSEFSLSRWERYMLFGICLLGSLACYAIACFMFPVLVLKPRKFVLLWTMGSLLAVLGFAIVQGFVAHFRQLTTMERLPITLSYFVTLLATIIATIKIKSTILSIVFGVLHILSFVAYLIAFFPFGTRTVSLGTRMASRSLSNWLP
What is the function of this protein?
Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.  Can be replaced by got1 (By similarity).
What are the official names of this protein?
Protein transport protein sft2.
What is the protein family that this protein belongs to?
Belongs to the SFT2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: Y2570_STAAR
Sequence: MIQSKKLTLGICLVLLIILIVGYVIMTKTNGRNAQIKDTFNQTLKLYPTKNLDGFYDKEGFRDQEFKKGDKGTWIVNSEMVIEPKGKDMETRGMVLYINRNTRTTKGYYFISEMTDDSNGRPKDDEKRYPVKMEHNKIIPTKPLPNDKLKKEIENLKFFVQYGNFKDINDYKDGDISYNPNVPSYSAKYQLNNDDYNVQQLRKRYDIPTKQAPKLLLKGDGDLKGSSVGSKNIEFTFVENKEENIYFTDSVQYTPSEDTRYESN
What are the official names of this protein?
Uncharacterized protein SAR2570.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NUD12_ARATH
Sequence: MSVLSSRTGRDRQRYDNNFRLVSGCIPYRLMKADETEEDSGVDFVNKLEVLMVSSPNRHDLVFPKGGWEDDETVLEAASREAIEEAGVKGILRELPLGVWEFRSKSSTVEDECLGGCKGYMFALKVTEELEDWPERKNRERRWLTVKEALELCRYEWMQRALEEFLRVMEDERRLRTEEETVHDSSKLEEESQIDPWYCFVVN
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Nudix hydrolase 12, mitochondrial, AtNUDT12.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Mitochondrion.