PharMolix/UniProtQA huggingface dataset:
Protein: PAK3_PONPY
Sequence: MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR
What is the function of this protein?
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation.  Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity.  Acts as downstream effector of the small GTPases CDC42 and RAC1.  Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues.  Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration.  Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments.  May also be involved in early neuronal development (By similarity).  In hippocampal neurons, necessary for the formation of dendritic spines and excitatory synapses; this function is dependent on kinase activity and may be exerted by the regulation of actomyosin contractility through the phosphorylation of myosin II regulatory light chain (MLC) (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PAK 3, Beta-PAK, p21-activated kinase 3, PAK-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPMT_YARLI
Sequence: MKPEFWQDRWNKDQIGWHQKSANPHLVKYWPTLNISQGSTVIVPLCGKSLDMRWLEGLGYNVLGVELSEKACKQYFDQMELEPKVSKNASGKFTIYEAGNTQIWCGDLFDLDADDVKYVSALYDRASVIALPPDMRERYAAHLGALIPDPQGLIITLDYDQSKMNGPPHAVSDAEVQRLFGTNWKLTLLEEVDKKDMFKEEGIEPVERVYKLN
What are the official names of this protein?
Probable thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAI3_MOUSE
Sequence: MAPKPPKSPKGQKKGKKNMKQQLLVPEEEEPMNMESMGHPEIYPLVLTTKTQEIFNCRVDEDMTDEQTYKLIKKEDILADLQNRAAVSDFHPVKKIVREYPGEELLLVYDKDFKYGLNFYLIGTEDGKENFLKPPEVPEEQEEPKEHVQEDVYVYNPPVSKPWVSLGSEKEIEEESVQESGKRVTYMISRKRSEFGAPVTFSDQNASSVKDAYIECTSYPEKNYTLSQVEKDVGLQVIAEVKDTSTQTKWAFPKNATTQYYPREFSEEEKSLIGKSKSLVDFFNNVSTSVEVALQQNEIMNTFIDDWKNLAEEESTFGDKTDTHLKEYQSFTDLHNTMEKMITCVSWHPTIFGLIVVSVAVRLSYEERVQNSGRLLLQPSLLLFWSFSDPIHPQLMLESPDDIFCFEFCPSDPNIIAGGCINGQIVLWDITAHADRIENIKTGGHRSKKTSLKPMFLLEPDSNKESMYIRHCAVSSIENGHRKVITDIHWLPDSFEINRMGSVFENRSGINCQLVTCSADCTICFWDIRPQKPAVTAAAAASAATTATNNANSQQSPVEKKKEENIDIPFDVPSTFLHLDLSWKPLSRLKLSKGDTSLDHCPTKLSLGEDPFLCKIQGTSSIHIILRDKMLSQIKMVKTSEINPYQNLEAGIANILKPIEDFCTKFFVGTEEGEVIYTDWKMERDSDTGRLMAKKPVSLYTVHDGAVHTIQRSPFFNDIVLTVGGWNVAIWKEEVMTGPLLQTCCGPKRYTAGHWSLTRPGVFYIGREDGNVDIWDLLEKTHEPAQSQNICITMITYIKPWTFSSKQQFIAVADYYGTLHILEIPWTLSHPSLNEVSSVNYYFEREVRHLEYVQQRKEIREQEKIDMALELVKKKAKIYQKTKEQMEAELKLEYESYLDLEKSVLFALGLSKVSEKKSYLDSH
What is the function of this protein?
Acts as a negative regulator of cell migration, invasion, and metastasis downstream of p53/TP53, through inhibition of Arp2/3 complex-mediated actin polymerization (By similarity).  Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function (PubMed:30060180).  May play a role in osteogenesis of dental tissue-derived mesenchymal stem cells (PubMed:25498833).
What are the official names of this protein?
Dynein axonemal intermediate chain 3, WD repeat-containing protein 63.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAP_TYCSV
Sequence: MQSSSPSTSHCSQIPIKIQHHIAKKRQVRRRRVDLDCGCSYYIHLDCINHGFTHRGVHHCASSNEWRLYLRDNKSPIFHDNQTQSEPIQQQIQHTNIPNQIQPQLEEGTGDSQMFSQLPHLDDLTVSDWSFFKSL
What is the function of this protein?
Strong activator of the late viral genes promoters.  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  TrAP suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway.  Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense.  Determines pathogenicity (By similarity).
What are the official names of this protein?
Transcriptional activator protein, TrAP, Protein C2, Protein L2.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae transcriptional activator protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=The phosphorylated form appears to accumulate almost exclusively in the nucleus, whereas the non-phosphorylated form is found in both nucleus and cytoplasm.
Protein: SPC19_KLULA
Sequence: MEEVLSEGVDALAACVDDMAKCLTVSKVTTDRSTKLAINMLQTKRVFQLVSEYDVQRARLDLMEDIEPLLQKLYSKLEKALTKLERERATLSQTFELNKLRFNNQESNPIIDNVKSDPVVIVSSTHEELERLKDLKNRKEELIQRIQELHEER
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit SPC19, Outer kinetochore protein SPC19.
What is the protein family that this protein belongs to?
Belongs to the DASH complex SPC19 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: DUT_MYCUA
Sequence: MSNSLAVVRLDPGLPLPSRAHDGDAGVDLYSAEDVVLPPGQRALVRTGVAVAIPFGMVGLVHPRSGLASRVGLSIVNSPGTIDAGYRGELKVVLINLDPATPIVVNRGDRIAQLLVQRVELLELVEVSSFDEAGLAATSRGDGGHGSSGGHASL
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: NDB47_ISOMC
Sequence: MKFQYLLAVFLIVLVVTDHCQAFFSLLPSLIGGLVSAIKGRRRRQLEARFEPKQRNFRKRELDFEKLFANMPDY
What is the function of this protein?
Has potent antibacterial activity against Gram-positive bacteria M. luteus, B. thuringiensis, S. aureus and B. subtilis, but not Gram-negative bacteria.  Shows a weak cytotoxicity effect against mammalian cell lines and relatively low hemolytic activity against human erythrocytes.
What are the official names of this protein?
Imcroporin, Non-disulfide-bridged peptide 4.7, NDBP-4.7.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Probably forms a helical membrane channel in the prey.
Protein: NUDJ_SHISS
Sequence: MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILKASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI
What are the official names of this protein?
Phosphatase NudJ.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudJ subfamily.
Protein: GCR_SAIBB
Sequence: MDSKESLTPGKEENPSSVLTQERGNVMDFCKILRGGATLKVSVSSTSLAAASQSDSKQQRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLQLLEESIANLNRSTSVPENPKSSASSSVSAAPKEKEFPKTHSDVSSEQQNLKGQTGSNGGNVKLYTADQSTFDILQDLEFSSGSPGKETNQSPWKSDLLIDENCLLSPLAGEEDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSSSNVTLPQVKTEKEDFIELCTPGVIKQEKLSTVYCQASFPGANIIGNKMSAISIHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPANKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSTVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQASSNLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQLPKYSNGNIKKLLFHQK
What is the function of this protein?
Receptor for glucocorticoids (GC).  Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors.  Affects inflammatory responses, cellular proliferation and differentiation in target tissues.  Involved in chromatin remodeling.  Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay.  Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth.  Mediates glucocorticoid-induced apoptosis.  Promotes accurate chromosome segregation during mitosis.  May act as a tumor suppressor.  May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic gene expression.
What are the official names of this protein?
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=After ligand activation, translocates from the cytoplasm to the nucleus (By similarity). In the presence of NR1D1 shows a time- dependent subcellular localization, localizing to the cytoplasm at ZT8 and to the nucleus at ZT20 (By similarity). Lacks this diurnal pattern of localization in the absence of NR1D1, localizing to both nucleus and the cytoplasm at ZT8 and ZT20 (By similarity).
Protein: FOLD_NITWN
Sequence: MAASIIDGKVIAADLRARVAGEVTRIKRDHGLTPGLAVVLVGNDPASEVYVRNKHKQTQAAGMASFEHMLPADVAQADVLALIAELNADPAVHGILVQLPLPKGLDTEAIIAAIDPAKDVDGLHPHNAGRLAGGLSALSPCTPLGCIILTKSVHASLEGLDAIVIGRSNLVGRPLVQLLLNENATVTIAHSRSRNLPELCRRADLVYAAVGRAEMVRGDWLKPGATVIDVGITRVPAAEGKTRLIGDVAFDEAMQVAGAVTPVPGGVGQMTVACLLVNTLRAACAIEGLSAPGV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PTH_DESAP
Sequence: MKLIVGLGNPGAKYRFTRHNAGFMVVDRLAGAAGTTVNRRRCFSLVGEGRLNGVRVVLAKPQTYMNLSGLAVSALCRHYRLELADLLVICDDLDLEFGRIRLRPKGGSGGHRGLASIIAALGSSDFPRVRIGIGKAEDASAHVLGEFAPEDQSGLEEILSTAALAAACACREGLDEAMSRFNSWRLMSANGTAEV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAT4_ARATH
Sequence: MASQGCVDWQFSGSDAAEKAAQASLGTYSSEIFSLCDPQGKPILPPLSEEAETSHTAEKAVVKAVLCGTGNAYAPSIGLPVAKRAVAEYLNRDLDNKLTGDDVYMTVGCKQAIELAVSILAKPKANILLPRPGFPWDMVHSIYKHLEVRRYEFIPERDFEIDFNSVREMVDENTFAIFIINPHNPNGNYYTEAHLKQLATLARELGIMVVSDEVYRWSVFGSNPFVPMGKFSSIVPVITLGSISKGWIVPGWRTGWLALHDLNGVFRSTKVLKAAKEFLEITSKPPTVIQAAIPTILEKTPQDFFEKRGIFLKDKVDFGYSKLKNIPTLTCYMKPESCTFLWTKLDPLHFVDIEDDHDFCRKLAKEENLVVLPGIAFGQNNWLRHSIDMETPRLEDAFERLKSFCERHSVIVEASSLKDVNGVN
What are the official names of this protein?
Probable aminotransferase TAT4, Tyrosine aminotransferase 4.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: PURA_LEIMA
Sequence: MPVRRYGGRYNSSSPGVSNALNPSRTAGWPLSPSPATGSKPASTHHDPVPQEAYYVKDEADARHQQQAPLREPSVEVEVEIIDDEPPRGSQKPLSVAPCTANANNSSGGSKCNAITASRYTFYTNAYQKSVYEALRSLRPLPELQEPRRVKEYAETSLKDSLYRIVEAHDVIMVAGAFFGDEGKGKTVDAVARHPLCTCIARVNSGENAGHTVYDKAGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFMEKEVIQLIDAGIDYRDRLFIGNVCIVTPYHKLLDLLGSAANSSTLKGMAPVHGSKVMKRGIRLDHIFNDDETLRKRLEKDMDTYFGLLKVKNLSDADVVRLCREENSDGVVRVPDYVIAFAQAEDKVEFLVKLYRDRVRHNPGFPARCDVTYELHAALLRGEKVLLEGPQSYWLSNARTKFWESTTSADTTAAGLLAASQLNFQKFKSVVLNVHKAPGSSRVGIGACPSSFVPQDYFSAQNIKTLRDLPSATCAHFEAVQRTLFRDGFPHSNDKARHNGIMAPVEYSDETGTYNIGVAMAIASAQHHGECGAVTKKPRVCGFFDCVLHHEVNNIQGPYLTISALDRGDEYDKVGVTIAYVYYSPEGKQVDVNGHVYKNGDIIRAGDPVPSEPALYHCHPIVKLIDGWRDNPIAAAKRRRNAPLPRGVCELLSAIEYFTNCKILSIGNGPNGDDIIYLRQ
What is the function of this protein?
Plays an important role in the salvage pathway for purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_FRATN
Sequence: MQEKISKFEDFLTQLQQNITTALEQHETNAAKFISDKWQKPDTPDQKLKGYGNSMIIEGGEIFEKGVVAFSRVHGSELPPSATAKRQELAGKSFIATGLSLVIHPRNPFVPTSHANFRIFIAGADTDTPIWWFGGGFDLTPYYPFEEDAIHWHQTAKNICDKHDKTYYSKFKKWCDEYFYLKHRDECRGVGGLFFDDLNDKSFDECFNFVTDCANSYLDAYIPIVAQRKNIEYSQKHKDFQLYRRGRYVEFNLVFDRGTIFGLQSGGRTESILSSMPPMASWRYNWQPEQNSEEAKVYQYIKPRDWIK
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAXL_ECOLI
Sequence: MIKSDQET
What is the function of this protein?
May serve a regulatory role in expression of downstream gene baxA; in a baxL-baxA-lacZ fusion mutation of the start codon to a stop codon in baxL increases expression of beta-galactosidase.
What are the official names of this protein?
Putative translational regulatory protein BaxL.
Protein: QOX2_STAEQ
Sequence: MSKFKSLLLLFGTLILLSGCSNIEVFNAKGPVASSQKFLIIYSIIFMLVIVAVVLSMFAIFIFKYSYKKNSESGKMHHNSLIETIWFVVPILIVIALAIPTVKTLYDYEKPPEKDKDPLVVYAVSAGYKWFFAYPDQHIETVNTLTIPKDRPVVFKLQSMDTMTSFWIPQLGGQKYAMTGMTMNWTLTADQLGTFRGRNSNFNGEGFSRQTFKVHSVSQNDFDKWVKEAKGKKTLSQDTFDKQLLPSTSNKELTFSGTHMAFVDPAADPEYIFYAYKRYNFEQKDPNFTAEEDLYKDVKDKPIKPARKVHITNPNYERHGMKPMILGNNEKYDNEFKKEEDHNSKEMEKISKGAKDENASKLHKKEHDDHGGGH
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.  Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I (By similarity).
What are the official names of this protein?
Probable quinol oxidase subunit 2, Quinol oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: QUEC_METEP
Sequence: MPEDAAVAGGETGALVLFSGGQDSATCLAWALDRFPHVETLGFDYGQRHRVELDRRAALRQGLTALDPAWGRRLGPDHTLALAALGEISDTALTRDSAIAFARDGLPNTFVPGRNLAFLTFAAALAYRRGLRHIVGGMCETDYSGYPDCRDDTIKALQVALNLGMERRFVLHTPLMWIDKAQTWALAETLGGRALVDLVVEESHTCYLGERGARHEWGYGCGTCPACDLRAKGFSRYLAARAE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: Y1410_ORYSJ
Sequence: MGVVSFSSTSSGASTATTESGGAVRMSPEPVVAVAAAAQQLPVVKGVDSADEVVTSRPAAAAAQQSSRYKGVVPQPNGRWGAQIYERHARVWLGTFPDEEAAARAYDVAALRYRGRDAATNFPGAAASAAELAFLAAHSKAEIVDMLRKHTYADELRQGLRRGRGMGARAQPTPSWAREPLFEKAVTPSDVGKLNRLVVPKQHAEKHFPLRRAASSDSASAAATGKGVLLNFEDGEGKVWRFRYSYWNSSQSYVLTKGWSRFVREKGLRAGDTIVFSRSAYGPDKLLFIDCKKNNAAAATTTCAGDERPTTSGAEPRVVRLFGVDIAGGDCRKRERAVEMGQEVFLLKRQCVVHQRTPALGALLL
What are the official names of this protein?
AP2/ERF and B3 domain-containing protein Os01g0141000.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL11_RHOCS
Sequence: MAKKIVGYIKLQVPAGKANPSPPIGPALGQRGLNIMEFVKQFNAKTADLEQGMPIPVVITAYGDRTFTFVTKTPPITYFLKKAAGIDKGSATVGRSGPVGRVTMEQVRDIATKKMKDLNANDVEGAARMIVGSARSMGIEVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DCN1_CAEBR
Sequence: MNRLKADQKTKVGKRKQDPPETLSEAEYDVKKCRAQNNANLVGVSNMTSSQTVMPITHLSYASSSSQGLAQSSILSKNCPKNYENILRQFVQWTQATEPVSLNFLAKANWNIEYAMTLYYDNPNLFSSSAPATVDQSKTIQLFTQYVDKRDGLGERIGPHGMQRLLIDLGYEPIDRRVLILAWVFKAETQCEFSLQEFTNGMASLQVDSIQGLKQKIDALDAGMKADLTKTRDLCIFTFNYGKSAASRSLDLEMAICYWDVIFGARKPLMSQWIDFLYGQERMAYARLEEELGPTNAKKVKSVWITRDTWNLFWDFIVLGKEDLSDYDEEGAWPVLIDQFVDHCRENLNYPKPLRENSNAMEHQSYY
What is the function of this protein?
Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes.  Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.  Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with rbx-1 to recruit the Nedd8-charged E2 enzyme to the cullin component of SCF-type complexes (By similarity).
What are the official names of this protein?
Defective in cullin neddylation protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPA_STRP4
Sequence: MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGLSVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLHVLKLSKIYREGNGSEKETKVD
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RL1_FRAP2
Sequence: MAKISKRMKEISAKIDAEKKYPVSEAFDILRDVSSVKFVESVDVSVALGVDPRKSDQVVRGASVLPNGTGKTVRVAVFAKGPAADAAKEAGADVVGMEDLADEVKKGNMDFDVVIASPDSMRVVGQLGQILGPKGLMPNPKVGTVTMDVAKAVRDAKAGQVRYRVDKAGIIHTTIGKVNFTSDALKQNLEQLLTDLKKAKPSVSKGIYLKKVSVSSTMGPGISVDFSDLNI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CSRA_THENN
Sequence: MLVLTRKVGERIVIGDDIVITVLKIEGNSVKIGIEAPKHVKILREELYEELKNENVKAASVSKDDLKEVWKNDKGYKRPGPSS
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_NITHX
Sequence: MQVNETLAEGLRHEFQISIPAAEITAKADARLVDLKDKVKLDGFRPGKVPVSHLKKMYGRSVMIETIEDTIRDTNMQIATDRGFKLAGNPKVTMPSEVKEIEDILAGKSDLSYSVAIEVVPAIELADFKTFSLEKPVVDVSDADVDEAIKRIADQNRSYSARAEGAKAENGDRVTISFKGTIDGELFEAGSSDDVLVVLGSNALIPGFEEQLVGIGAGETRVVKTSFPSNYMENDLAGKDAEFETKASLIEAPQDIKIDDEFAKLLGLEELDQLKQVVREQLSAEFARAMRQHLKRALLDRLDDTHKFDAPPSLVEEEFEQVWKTVTTEMETNKKTFADENTTEEAARVEYRQIADRRVRLSLVLSDIGEKNGIKVTDDEINRAVISRARQTPGREKEIWSYYQKNPQALAQVRAPLFENKVVDFILELATVTEKKVTREDLFKDHEAHSTEA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CARB_STRGG
Sequence: MPKRSDIQSVLVIGSGPIVIGQAAEFDYSGTQACRVLKAEGLRVILVNSNPATIMTDPEIADATYVEPITPEFVEKIIAKERPDALLPTLGGQTALNTAISMHDNGVLEKYGVELIGANVEAINKGEDRDLFKGVVEAVKEKIGYGESARSVICHSMDDVIAGVDTLGGYPVVVRPSFTMGGAGSGFAHDEEELRRIAGQGLTLSPTTEVLLEESILGWKEYELELMRDRNDNVVVVCSIENFDPMGVHTGDSITVAPAMTLTDREYQRLRDVGIAIIREVGVDTGGCNIQFAIDPTDGRVIVIEMNPRVSRSSALASKATGFPIAKIAAKLAVGYTLDEIPNDITEKTPASFEPTLDYVVVKAPRFAFEKFPSADSSLTTTMKSVGEAMAIGRNFTEALQKALRSLEKKGSQFAFTGPVGDKAELLAEAVRPTDGRINTVMQAIRAGATQEEVFDATKIDPWFVDQLFLIKEIADELASAERLDAGLIAEAKRHGFSDAQIGGIRGLREDVVREVRHALGIRPVYKTVDTCAAEFAAKTPYFYSSYDEESEVAPRTKPAVIILGSGPNRIGQGIEFDYSCVHASFALSDAGYETVMVNCNPETVSTDYDTSDRLYFEPLTLEDVLEIVHAESLAGPIAGVIVQLGGQTPLGLSQALKDNGVPVVGTSPEAIHAAEDRGAFGRVLAEAGLPAPKHGTATTFAEAKAIADEIGYPVLVRPSYVLGGRGMEIVYDETRLASYISESTEISPTRPVLVDRFLDDAIEIDVDALYDGTELYLGGVMEHIEEAGIHSGDSACALPPITLGGFDIKRLRASTEGIAKGVGVLGLINIQFALSGDILYVLEANPRASRTVPFTSKATAVPLAKAAARISLGATIAELRAEGLLPRTGDGGTLPLDAPISVKEAVMPWSRFRDIHGRGVDTVLGPEMRSTGEVMGIDSVFGTAYAKSQAGAYGPLPTAGRAFISVANRDKRSMIFPARELVAHGFELMATSGTAEVLKRNGINATVVRKQSEGTGPNGEKTIVQHIHDGEVDLIVNTPYGTGGRLDGYEIRTAAVARSVPCLTTVQALAAAVQGIDALNHGGVGVRSLQEHAEHLTAARD
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: GUAA_CAMJE
Sequence: MKKADILVLDFGSQYTQLIARRLREQGVYAEILPFNVSLADIKAKEPKGIILSGGPASVYATDAYFCDKGIFDLNLPVLGICYGMQLMAHHYKATVAPAGHKEYGKANIEIKKDNALFKNLPKKQTVWMSHSDKVENLPQGFEVLATSENSPFCVFGNEDKKFFALQFHPEVQHSEFGKNILKNFAKYACNCESIWNMGSFAKTQAEKIREEVGNDKVLCAVSGGVDSSVVAALLASAIKEQIIVVFVDNGLLRSGEKEQVEFMFKNTLGIDLISIDASEIFLSRLVNVTDPEQKRKIIGNTFIEVFEEEAKKHKDVKYLAQGTLYTDIIESSVVGASKTIKSHHNVGGLPEKMNLKLIEPLKEIFKDEVRALGLELGLSKEVVYRHPFPGPGLAIRIMGEVNRASLELLRKADVILLEELKSTGWYDKTWQAFCVLLNVKSVGVMGDNRTYDNAVCIRVVDASDGMTATFSHLPYEILENISRRIINEVEGINRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.