PharMolix/UniProtQA huggingface dataset:
Protein: MET_RABIT
Sequence: MKAPAVLAPGILVLLFTLVPRSHGECKEALVKSEMNVNMKYQLPNFTAETPIQNVLLHQHHVYLGAINHIYVLNDKDLQKVAEYTTGPVLEHPDCLPCQDCSSKANSSGAVWKDNINLALLVDKYYDDQLISCGSVNRGTCQRHVLPPDNPADIQSGVYCMFSPQADEEPGQCPDCVVSPLGAKVLLSKKQRFIYFFVGNTINSSYLPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQKETLDAQTFHTRIIRFCSKDSGLHSYMEMPLECILTEKRRKRATREEVFNILQAAYVSKPGAHLARQIGATPNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYINEFFNKIVNKNNVKCLQHFYGPNHEHCFNRTLLRNSSDCEARSDEYRTELTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVISRTILNVPHVNFRLDSHPVSPEVVVEHPLNQNGYTLVVTGNKITKIPLNGLGCGHFQSCSQCLSAPPFVQCGWCHDKCVPSEECPSGTWTQEICLPAIYKVFPASAPLEGGTTLTICGWDFGFRKNNKFDLKKTKVLLGNESCALNLSESTTNTLKCTVGATTHEHFNMSITVSNSRGRTQYSTFSYVAPVITSISPSYGPKAGGTLLTLTGKYLDSGNSRHISIGGKTCTLKSMSNSILECYTPAQTISTEFPVKLEIDLASRETSSFSYREDPIVDEFYPTKSFISGGSTITGVGKNLDSVSVPRMVISVHEAGSNFTVACQHRSNSEIICCTTPSLQQLNLHLPLKTKAFFMLDGILSKHFDLTYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSDSEAVLCTVPNDLLKLNSELNIEWKQAVSSTVLGKVIVQPDQNFMGLIVGGVSISIILLLLLGLFLWLKKKKRIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFSEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISTIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNVDGTVDT
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NXN_HUMAN
Sequence: MSGFLEELLGEKLVTGGGEEVDVHSLGARGISLLGLYFGCSLSAPCAQLSASLAAFYGRLRGDAAAGPGPGAGAGAAAEPEPRRRLEIVFVSSDQDQRQWQDFVRDMPWLALPYKEKHRKLKLWNKYRISNIPSLIFLDATTGKVVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLRNNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSEESFKQYFSEMPWLAVPYTDEARRSRLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAAQLNEGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYKAKEEEAPLLFFVAGEDDMTDSLRDYTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEAFVNDFLAEKLKPEPI
What is the function of this protein?
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex.  May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity).
What are the official names of this protein?
Nucleoredoxin.
What is the protein family that this protein belongs to?
Belongs to the nucleoredoxin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: PYRB_ACIBY
Sequence: MHIAALHQPSQVQLNQDGNLKHFLTIEGLSKENLTKILDTAQSFLDDNNNLINRPLLEGRTVMNLFFENSTRTRTTFEAAAKRLSANVLNIDIARSSTSKGETLRDTLWNLEAMAADIFVVRHSSSGAAHFIAKDVCPKVAIINAGDGRHAHPTQAMLDMLTIRRETKKSFEDLSVAIIGDIKHSRVARSDVAALQTLGCKDIRVIAPNTLLPVGFSEYGDHVRLFNNMDEGITGCDVIIALRIQNERIDSPALSSQSEFYRMYGLNKERLSLAKPDCIVMHPGPMNRGVEIDSSIADGEQSVILKQVTNGIAVRMAVLALSMQGQLQEQGLIEAIAL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: UREF_RHOPB
Sequence: MATSTNSQDDAALSAAQAAALYRLMTWLSPAFPVGAFSYSSGIEWAVEAGDVVDAPTLQAWLAAMLSHGTGFCDAVLLAHAHRAVISNDDDALRSLAELACAYVSSRERHLETTAQGRAFVEIARAAWANGRLERAVADCAGLTAYPVAVGIVSAAHGVPLAATLHGFLHAVVSNWISAGARLIPLGQTDSQRLIAALEPAVIATGARALIASLDDLGGATFRADLASLQHEAQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_SALPK
Sequence: MRHPLVMGNWKLNGSRHMVNELVANLRKELAGVAGCDVAIAPPEMYIDLAKRAAAGSHIMLGAQNVDLNLSGAFTGETSAEMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKADAKIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 242L_IIV6
Sequence: MEEKNGWNIYMVTMKNGNIYTGISNNVLKRFDTHCNGKGAKCLRGKGPLKLSWFSKANYSHGEAASLEYTIKKQTKKVKLQIIKLNVLDVKTFLNGKMK
What are the official names of this protein?
Putative GIY-YIG domain-containing protein 242L.
Protein: LACG_STAEQ
Sequence: MTKKLPDDFIFGGATAAYQAEGATQTDGKGRVAWDTYLEENYWYTAEPASDFYNRYPVDLELSERFGVNGIRISIAWSRIFPKGYGEVNQKGVEYYHNLFKECHKRHVEPFVTLHHFDTPEVLHKDGDFLNRKTIDYFVDYAEFCFKEFPEVKYWTTFNEIGPIGDGQYLVGKFPPGIKYDFEKVFQSHHNMMVAHARAVKLFKDENYKGEIGVVHALPTKYPYDPSNPEDVRAAELEDIIHNKFILDATYLGKYSRETMEGVQHILSVNGGQLEISDEDYKILDEAKDLNDFLGINYYMSDWMRGFEGESEITHNATGDKGGSKYQLKGVGQREFDVDVPRTDWDWMIYPQGLYDQIMRVVKDYPNYHKIYITENGLGYKDVFDEKEKTVHDDARIDYIKQHLSVIADAIADGANVKGYFLWSLMDVFSWSNGYEKRYGLFYVDFETQERFPKKSAYWYKELAESKEIK
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: YYAP_BACSU
Sequence: MTNNLKQRRIILDLAVTLDGFIEGKNGEVDWCIMDPDMGFTDFLNQIDTILYGRKSFDLWGQYIPKNEDPDTEKELWKLVHSKKKYVFSRTQNEIDNQAIFINDNILEEVNKLKKNPGKDIWLYGGASLITTFINLGLVDEFRLSIHPVVLGEGKPLFIDVKQRINLKMVNTRTFSSGVVQIVYHWNG
What are the official names of this protein?
Uncharacterized protein YyaP.
What is the protein family that this protein belongs to?
To B.subtilis YwjB.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TBA_POPEU
Sequence: AIFVDLEPTVIDEVRSLDIERPTYTNLNRFDGAINVDVTEFQTNLVPYPR
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GCSH_LISMO
Sequence: MSLPKDLLYTEEHEWVKADDGSYVIGITDFAQDQLGDIVFVELPEVGDTVTKGDSIGSIESVKTVSDFYAPVTGKVVAVNETLEDEPELINSNPYDTGWILKLEEVEEADVKALLSSDDYEKVLD
What is the function of this protein?
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
What are the official names of this protein?
Glycine cleavage system H protein, Octanoyl/lipoyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RIBL_HALMD
Sequence: MVTRDVVAQGTFDILHPGHVHYLREAKAMGDRLHVIVARSENVTHKAPPVVPDRQRVEMVEALDPVDYARLGHAEDIFVPIEQIEPDVIALGYDQHHEVEGIETALDERGLDCEVRRAGPRKASEDEILSTGSIIEKILDERS
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: REG4_HUMAN
Sequence: MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQPIWIGLHDPQKRQQWQWIDGAMYLYRSWSGKSMGGNKHCAEMSSNNNFLTWSSNECNKRQHFLCKYRP
What is the function of this protein?
Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment.  May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.
What are the official names of this protein?
Regenerating islet-derived protein 4, REG-4, Gastrointestinal secretory protein, REG-like protein, Regenerating islet-derived protein IV, Reg IV.
What are the subcellular locations of this protein?
Secreted.
Protein: PHYLL_TOBAC
Sequence: MASAKIFLIFLLAALIATPAAFAILVPTLVSTHISGLVFCSVNGNLDVINGLSPQVFPNASVQLRCGATNVISSTITNGSGAFSLAVNTFPLLNCNLVVATPLSTCNATLQSVGRLASSLRLVNITLGSGTGLIRVGLAPTGFILNLNIN
What is the function of this protein?
Inhibits spore germination and leaf infection by fungal pathogens.
What are the official names of this protein?
Phylloplanin, T-phylloplanin.
What are the subcellular locations of this protein?
Secreted.
Protein: XKR4_TETNG
Sequence: MAAKSDGVLKMKKSDVAFTPLQNSEHSGSVQGLHPGAQPDSAGAGDADFANGESRCCGGGGSHSTCLRLSREQQKYTVWDCLWIVAAVAVYVADVGSDVWLSVDYYLEEDYWWFGLTLFFVVLGSFSVQLFSFRWFVHDFSTEDSAEAAADGSHMDGNKLLSGSASHGDVTAQHHPATPQRQASTASRNTTTNSTASTGLGPRGPKRPAYYTFCVWGSQSVIHILQLGQIWRYIHTIYLGVQSRQSAETERWRYYWRMVYEFADVSMLHLLATFLESAPQLVLQLCIIIQTHKLLAVQGCRLFIYYLLILAENAALSALWYLYRSPLATDAFAVPALCVIFSSFLTGVVFMLMYYAFFHPNGPRFGRSMSGHGLNLDPTAQFSTLPSEVATNSLRSNRGATATLERDAGKYSERDGCMPVFQVRPTVPSTPSSRAPRLEETVIKIDLCRNRYPAWERHVLDRSIRKAILAVDCSLTPPRLQYKDDALVQERLEYETTL
What is the function of this protein?
Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface.  Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment.
What are the official names of this protein?
XK-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL16_STAES
Sequence: MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEYGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVPEEVAREALRLASHKLPVKSKFVKREELGGETNES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CKL8_ARATH
Sequence: MDRVVGGKYKLGRKLGSGSFGELFLGVNVQTGEEVAVKLEPARARHPQLHYESKLYMLLQGGTGIPHLKWYGVEGEYNCMVIDLLGPSMEDLFNYCSRRFNLKTVLMLADQMINRVEYMHVRGFLHRDIKPDNFLMGLGRKANQVYIIDYGLAKKYRDLQTHRHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLMYFLRGSLPWQGLRAGTKKQKYDKISEKKRLTPVEVLCKSFPPEFTSYFLYVRSLRFEDKPDYPYLKRLFRDLFIREGYQFDYVFDWTILKYPQFSSGSSSSSKPRSSLRPAMNPPVPIAERPDKPSAGAGQDSRDRFSGALEAYARRNGSGSGVVQADRSRPRTSENVLASSKDTTPQNYERVERPISSTRHASSSRKAVVSSVRATSSADFTENRSSRVVPSNGRSSTAQRTQLVPDPTTRPSSSSFTRAAPSRTARDITLQSFELLTIGNGKRK
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  It can phosphorylate a large number of proteins.
What are the official names of this protein?
Casein kinase 1-like protein 8, Protein CASEIN KINASE I-LIKE 8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, plasmodesma. Note=Present in punctate particles with granular structure.
Protein: LPXB_BRADU
Sequence: MMQGRDPKRKIFLIATEESGDRLGSALMKVLRQRLGDGVQFEGVGGRTMAREGLETLFPIEELSIVGFAAVVQQLPKILRLIRETADAVLEAVPDALVIIDSPDFTHRVARRVRARNPAIPIVDYVSPQLWAWRPGRARTMLGYVDHVLGLLPFEPEEYRKLGGPPCSYVGHPLIEQLGSLRPNAEEQKRRNSELPVLLVLPGSRRSEIRHHIEVFGAALGRLQAEGRAFELMLPTMPHLEATVREGIASWPVKPQIVIGEAEKRAAFRIAHAALAKSGTVTLELALSGIPMVTAYRVGAIEAFILRRAIRVSSVILANLVIGEDVIPEFLQEDCTPEKLAPALSEVLTDSDMRRRQVEAFARLDTIMSTGNKAPSVLAADIVLATMRKGRR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: KAD_PHOPR
Sequence: MRIILLGAPGAGKGTQAQFIMAKFGIPQISTGDMLRAAIKAGTELGKQAKSVIDAGQLVSDDIILGLVKERIAQDDCAKGFLLDGFPRTIPQADGLKEVGVVVDYVIEFDVADSVIVERMAGRRAHLASGRTYHNVYNPPKVEGKDDVTGEDLVIREDDKEETVLARLGVYHNQTAPLIAYYGKEAEAGNTQYLKFDGTKAVAEVSAELEKALA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y326_SHEDO
Sequence: MAIKDWPQGEGPRDKLLQQGAARLSDAELLAVLIRNGISGQNALTTGRLLLSHFGGLRSLMTATEDKVCQIPGVGPVKYAQLQAAAEISKRISRENLQRGQILTNPDLTRDYLMRQLADRSYEVFALLLLDSQHRVIQFVELFRGTIDSASVYPREVVSLVLEKRAAAVIICHNHPSGIAEPSQADRRITERLKNALATIDVSLLDHMVVGDFEIVSFAERGWLN
What are the official names of this protein?
UPF0758 protein Sden_0326.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RECA_BURCE
Sequence: MTAEKSKALAAALAQIEKQFGKGSIMRMGDGEAAEDIQVVSTGSLGLDIALGVGGLPRGRVVEIYGPESSGKTTLTLQVIAELQKLGGTAAFIDAEHALDVQYAAKLGVNVPELLISQPDTGEQALEITDALVRSGSIDMIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGSIKKNDEVIGNETRVKVVKNKVSPPFREAIFDILYGEGISRQGEIIDLGVQAKIVDKAGAWYSYNGEKIGQGKDNAREFLRENPEIAREIENRIRESLGVVAMPDGAGNEAEAMDEEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_EXIS2
Sequence: MSQAIMKQAEERMEKAHLSLKKELATLRAGRANVSILDPVQVDYYGSPTPLNQVANVNTPEARLILITPWDKSMVTEIEKAIQRADLGLAPSSDGTVIRLAIPPLTEDRRKELVKLVKKYTEEGKVALRNIRRDTNEQLKKQEKDGVLTEDDLRGYTEDVQTLTDKFVKVLDQTAADKEQEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_STRP2
Sequence: MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEKGKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELLAKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAVDRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVNSGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHKVIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFDYRDVNDEESIRLGELLAKQLVKDVVIQVTGLDDQELIEQIVEYI
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RL31_THEVO
Sequence: MPDDEVSKEIIMNIPLREAKLSSRKRRADTSISILRNYVSKKLKVDTSKIWIDPKVSETIWKKGREKPPSKLSLKIIKLEEGTTEIILP
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: CLD15_RAT
Sequence: MSIAVETFGFFMSALGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWYSCATDSLGVSNCWDFPSMLALSGYVQGCRALMITAILLGFLGLFLGMVGLRCTNVGNIDLSRKAKLLAIAGAFHILAGACGMVAISWYAVNITTDFFNPLYVGTKYELGSALYLGWSASLLSILGGICVFSTCCCDSKEDPATRVGLPYKPSTVVTARATSDESDVSFGKYGKNAYV
What is the function of this protein?
Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia.  While some claudin family members function as impermeable barriers, others mediate the permeability to ions and small molecules.  Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability.  CLDN15 forms tight junctions that mediate the paracellular transport of small monovalent cations along a concentration gradient, due to selective permeability for Na(+), Li(+) and K(+) ions, but selects against Cl(-) ions.  Plays an important role in paracellular Na(+) transport in the intestine and in Na(+) homeostasis.  Required for normal Na(+)-dependent intestinal nutrient uptake (By similarity).
What are the official names of this protein?
Claudin-15.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Note=Tight junctions form continuous circumferential cell-cell contacts at the borders of apical and lateral cell membranes that seal the intercellular space and show up as strand- like structures in electron microscopy.
Protein: SP0F_BACTK
Sequence: MEGKILIVDDQYGIRVLLHEVFQKEGYQTFQAANGFQALDIVKKDNPDLVVLDMKIPGMDGIEIFKACKEIDESIKVILMSAYGELDMIQEAKDLGALMHFAKPFDIDEIRQAVRNELAVEA
What is the function of this protein?
Key element in the phosphorelay regulating sporulation initiation.  Phosphorylation of spo0B during sporulation initiation (By similarity).
What are the official names of this protein?
Sporulation initiation phosphotransferase F, Stage 0 sporulation protein F.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GOOX_SARSR
Sequence: MVRIQELTAALSLASVVQASWIQKRNSINACLAAADVEFHEEDSEGWDMDGTAFNLRVDYDPAAIAIPRSTEDIAAAVQCGLDAGVQISAKGGGHSYGSYGFGGEDGHLMLELDRMYRVSVDDNNVATIQGGARLGYTALELLDQGNRALSHGTCPAVGVGGHVLGGGYGFATHTHGLTLDWLIGATVVLADASIVHVSETENADLFWALRGGGGGFAIVSEFEFNTFEAPEIITTYQVTTTWNRKQHVAGLKALQDWAQNTMPRELSMRLEINANALNWEGNFFGNAKDLKKILQPIMKKAGGKSTISKLVETDWYGQINTYLYGADLNITYNYDVHEYFYANSLTAPRLSDEAIQAFVDYKFDNSSVRPGRGWWIQWDFHGGKNSALAAVSNDETAYAHRDQLWLWQFYDSIYDYENNTSPYPESGFEFMQGFVATIEDTLPEDRKGKYFNYADTTLTKEEAQKLYWRGNLEKLQAIKAKYDPEDVFGNVVSVEPIA
What is the function of this protein?
Catalyzes the selective oxidation of C1 hydroxyl moieties on mono- and disaccharides with concomitant reduction of molecular oxygen to hydrogen peroxide.  This results in the formation of the corresponding lactones, which typically undergo spontaneous hydrolysis.  Glucooligosaccharide oxidase is able to oxidize the monosaccharide D-glucose as well as the disaccharides maltose, cellobiose, and lactose.  In addition, it shows high selectivity for cello- and maltooligosaccharides, indicating that glucooligosaccharide oxidase prefers oligosaccharides with a beta-D-glucosyl unit on the reducing end and additional sugar units linked by alpha- or beta-1,4 glucosidic bonds.
What are the official names of this protein?
Glucooligosaccharide oxidase, GOOX.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDR4A_XENLA
Sequence: MKLLGHKIELWAGLLLPDVSISGMSELRFPEEKPLLRGQDTEMESADTFLSAADTDWKEHDIETPYGMLHVVIRGTPKGNRPAILTYHDVGLNHKLCFNTFFNYEDMQEITKHFVVCHVDAPGQQVGASQFPQGYQYPTMDQLAAMLPSVMQHFGFQSIIAIGVGAGAYVLAKFALIFPELVEGMVLINIDPNGKGWIDWAASKISGLASSLPETVLSHLFSQEELMNNTELVQNYRQQISNCVNQSNLQLFWNMYNSRRDLEMSRPGTAPNAKTLRAPVMLVVGDNAPAEECVVECNSKLDPTNTTFLKMADSGGLPQVTQPGKLTEAFKYFLQGMGYMPSASMTRLARSRTASLTSASSVDGSRPRPCTQSESSDGIGQINHTMEVSC
What is the function of this protein?
Contributes to the maintenance of intracerebral BDNF levels within the normal range.  May enhance growth factor-induced ERK1 and ERK2 phosphorylation.  May attenuate growth factor-promoted ELK1 phosphorylation in a microtubule-dependent manner (By similarity).
What are the official names of this protein?
Protein NDRG4-A.
What is the protein family that this protein belongs to?
Belongs to the NDRG family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.