PharMolix/UniProtQA huggingface dataset:
Protein: TRMB_STAAW
Sequence: MRVRYKPWAEDYLKDHPELVDMDGQHAGKMTEWFDKTQPIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMSLTNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSNKGSRIYRMEAKFHSQK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: NRDR_BRUA1
Sequence: MRCPYCQSEDTQVKDSRPAEDGAVIRRRRVCSVCGGRFTTFERVQLRDLMVVKKSGRRVPFDRDKLTRSIEVALRKRDVDSERVERAISGIVRQLESAGEAEVTSDEIGRLAMDALKGIDDIAYIRFASVYRNFSKAVDFHNVIDELTVSETGDNLET
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: AMZA_HALWD
Sequence: MLVDIVPIGDLPAQVKREASAALRGVYECDVTVHEEQSIPDGAFDHSRSQYRAEQFIELASRIGSGEKNIGITAEDLYYRRRNYVFGLAYLNGNGSVISTYRLQTSSDGGLKSKSPDAVFADRIRKEVVHEIGHTFGLEHCDNSKCVMSFSPTVREVDVKEENLCGSCNRLLY
What is the function of this protein?
Probable zinc metalloprotease whose natural substrate is unknown.
What are the official names of this protein?
Archaemetzincin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M54 family.
Protein: DNAA_GEOSM
Sequence: MENIWLEAQTNLKQVLTEQTYSTWIDPLKFLGATVDTIVLEVPSSFFQKWVTDKYLAMIKEAISAVNGKSYQIEFHVADEKPEAAPEEKPEKEGKPAREKEKDKDKEKEKDREKEKDKKELVPNLNPKYTFESFVSGPSNQFAYAASQAVANKPATNYNPLFIYGGVGLGKTHLVNAIGNHILAKNPKAKICYYSSEKFMNEMINSLRYKKMDEFRNKFRKMDLLLIDDIQFMAGKEATQEEFFHTFNALYESHKQIVVTSDKFPKDIPGLEERLRSRFEWGLIADIQPPGVETKVAILKKKSDMHAVNLPDDVALFLAEGANSNIRELEGMLIRLEAFASLTGQEITLSMAREVMKDIIVEKTRDITVEMIQKTVAEHFRIKVSELKSDKRIKTLVVPRQIAIYICRELTKASYPEIGEKFGGKDHSTIIHSVKKIEKQMAGDDEFKASVEDIRKKLFT
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K6_VACCC
Sequence: MSANCMFNLDNDYIYWKPITYPKALVFISHGAGKHSGRYDELAENISSLGILVFSHDHIGHGRSNGEKMMIDDFGTARGNY
What are the official names of this protein?
Protein K6.
What is the protein family that this protein belongs to?
Belongs to the poxviridae K6 protein family.
Protein: PSAE_TRIV2
Sequence: MVQRGSKVRILRPESYWFQDVGTVASVDQSGIKYPVIVRFDKVNYSGINTNNFAVDELIEVEAPKAKPAKK
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: ATG39_YEAST
Sequence: MSEEDDHWNLVRLRRLRKGREGEEQSSKSEISLDSLHESSFAGEDDEDFDADVLSNTSSEESAQMNRIYDFRTSNEFSNAGVNIDQTGVPTISESFDTLSGSNVGGTVLPSMEGSKLKDSTIRNSSTLSDHIIDKSEGKSAKLKMWHVIMLSSLLSMTFSYLALEYSLTGDVLAGFKSQQSLRNNERKLLYGNIDFVDKKSYDSSSDSLSQWAPSGKYYVDFDNHIAYPLKDDDLMGWRRYKTDLVILWYTTKARMKDGWHKRINKINGGRIKLHLFLKNSFKSAQESLRVLHKEQKRRWKRLFVLLHNKYRQFSPHIKRYFDHSCQKAKQCWSGSRLQLRKLRFKSMKPFRVFQFKVRKDTNWFVKQLKRFGLKLQHSRMYKAMSECRKKNYFKCKH
What is the function of this protein?
Acts as a receptor for reticulophagy and nucleophagy.  Directs autophagic sequestration of double-membrane vesicles derived from the nuclear envelope and perinuclear endoplasmic reticulum (pnER) into autophagosomes.  Is not required for the cytoplasm-to-vacuole targeting pathway, mitophagy, pexophagy, and non-selective autophagy.
What are the official names of this protein?
Autophagy-related protein 39.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass membrane protein.
Protein: MSHR_PAPAN
Sequence: MPVQGSQRRLLGSLNSTPTATPHLGLAANQTGARCLEVSVPDGLFLSLGLVSLVENVLVVTAIAKNRNLHSPMYCFICCLALSDLLVSGSNMLETAVTLLLEAGVLAARAAVVQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVLFSTLFIAYYDHAAVLLCLVIFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRLAHQGFGLKGAATLTILLGIFFLCWGPFFLHLTLIVLCPQHPTCSCIFKNFNLFLALIICNAIIDPLIYAFRSQELRRTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SC61A_NEUCR
Sequence: MSSLRFLDLVKPFVPFLPEVQQPETKIPFNQKLMWTGLTLLIFLVMSQMPLYGIVSSDTSDPLYWLRMMMASNRGTLMELGITPIISSGMVFQLLAGTHMIDVNLDLKADRELYQTAQKLFAVILSIGTATVYVFTGLYGPPSDLGAGIVFLLILQLVVAGMIVILLDELLQKGYGLGSGISLFIATNICESIMWKAFSPTSINTGRGPEYEGAVIALFHLLMTWDNKQRALYEAFYRQNLPNIMNLLATLVVFAAVIYLQGFRVEIPVKSSRQRGARGSYPIRLFYTSNMPIMLQSALSSNVFLISQMLYSRFSENLLVRLFGVWEAKEGTAQLSAVSGLVYYMSPPLNFKDALLDPIHTAVYIAYMLTACAVFSKTWIEVSGSSPRDVAKQLKDQGLVMAGHREQSMYKELKRIIPTAAAFGGACIGALSVASDLMGALGSGTGTLLAVTIIYGYFEIAAKEGDLQGMKGMIMG
What is the function of this protein?
Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER.  It is required for assembly of membrane and secretory proteins and is essential for cell growth.  It interacts with other membrane proteins required for protein translocation.  Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event.  A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity).
What are the official names of this protein?
Protein transport protein SEC61 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PGK_ROSS1
Sequence: MAKKTIRDIDWSGKRALVRVDFNVPLENGQITDDTRIRAALPTIRYLLEHGAAVILMSHLGRPKNKVVESMRLAPVVARLAELLPEAKAIKGTQATTGPAAEAAAQDLKPGEVLVLENTRFDPREEANDESMARELAKLGDVYVNDAFGSAHRAHASTEGVARFLPAVAGFLMEAELAALQGALENPTRPFVTIIGGAKISDKIGVIENLLGKVDALLIGGGMANTFLLAQGYEMGDSLVEPDSVPVAKDLLEKAASRGVRFMLPTDVVIADAFSADANRRVVSVGDIPPGWRVLDIGPETVRAYTEIITTAQTVIWNGPMGVFELAPFAEGTRAIAQAMANCPGMTIVGGGDSVAAVEQMGLADKIRHISTGGGASLELLEGRILPGVAALNDA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LONM_CRYNJ
Sequence: MLPLRAFARLAQRPRLSRPTQLARSSLPRPSPSRPAAHYLALAPAPSTRFLHSSPPVLKEKRWLNNTPPEDDGEDGQNPKQDDQVEKPLPDAESSKSAEERAKSQSSKPDIKASSSDSVSSSAPAPGSADGGSPPGAGGPKEVAKPVIPEIYPQVLAIPITHRPLFPGFYKAVTVRSPPVIKAIRELQAHGQPYVGAFLLKDSTVDSDVVTDINQVQPVGVFCQITSCFTSQEGEGKPEALTAVLFPHRRIKINELVKSSGTKGDGTVGVGGLVEGSQDSAKGEGEVKSFESEVPGVEEVREELGTVSIDSEQPDVHKENRDLETKEVTQIDFLHSLLPQVSLTNVSNLSIEPYEKDSQVIRAIMSELISVFKEIAQLQPMFREQVTSFAISNTSSQVFDEPDKLADLAAVVSTADVSDLQAVLSSTSIEDRLQRALVLLKKELINAQLQFKISRDVDTKIQKRQREYYLMEQLKGIKKELGMESDGKDKLVEGFKEKASKLAMPEGVRKVFDEELNKLVHLEPAASEFNVTRNYIDWLTQVPWGVHTPENYNISHAIKILDEDHYGLKDVKDRILEFMAIGKLRGSVEGKILCLVGPPGVGKTSIGKSIAKALGRQFFRFSVGGLTDVAEIKGHRRTYIGAMPGKPIQALKKVATENPLILIDEVDKISKAYNGDPASALLEMLDPEQNKSFLDHYLDVPIDLSKVLFVCTANVLETIPGPLLDRMEVLEVSGYVSAEKMNIAERYLSPQAKVAAGLEDVNIELEPGAIEALIRYYCRESGVRNLKKHIDKIYRKAAFKIVTDLGESGLPEPATPPAENQVEAQYPDIKPASELTYNVIPGTEVSGVDTKTDVTTVPREPMKVPAGIHVKVTQENLKDYVGPPLYHKDRLYTHSPPAGVSTGLGYLGNGSGAVMPVEINSMPGKGNLQLTGKLGEVIRESAQIAMSWVKSNAYLLGITKSEAEATLNDRDVHLHMPEGGIGKEGPSAGTAILTAFVSLFTKTRVDPDIAMTGEISLLGQVLPVGGLKEKILAAHRAGIKKLIVPAGCKPDIDENVPESVKGGIEFVFVEDVRQVLHEAFRGTEVEKRWQETLPMEEEPQRERH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix.  May also have a chaperone function in the assembly of inner membrane protein complexes.  Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome.  Binds to mitochondrial DNA in a site-specific manner.
What are the official names of this protein?
Lon protease homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: AROB_CAUVC
Sequence: MIRTVPVGLGERAYDVVIGPGLLDQAGERVAAVLGKRKRVAVVTDAHVGAHHGERLSAALQGAGITVDLITIAPGEESKSFEGLADLSDRLLALNLERGDQIVALGGGVVGDLAGFAAAIYKRGIDFVQVPTTLLAQVDSSVGGKTAIDTPRGKNLIGAFHQPRLVLADLDVLATLPARELACGYAEIIKYGLLGDFAFFEWLETNVQAVLDRDVDALVRAVGRSVEMKAEIVAEDEKEAGRRALLNLGHTFGHAIEAEMGFGEALKHGEAVGVGMAQAFRFSARLGLCPSQDAVRAQAAIKAAGLPTTLADVRPEPFSADALIAHCGQDKKAQGGKLTFVLARGIGDAFVAKDVDRAALKAFLVEEGAV
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBAD_EMENI
Sequence: MTEQPPQNHSVDLNQNEDNNENDYRSSSATDAERPCEPKIEESTAKPPTGPPAPPPPPNGGLVAWLHVIGGFMLFFNTWGIMNAFGVFQTYYESGALFERSSSDISWIGSIQATMLLLVGFFTGSIYDRGYLRALLVVGSFCIVFGHMMLSLCKTYGQVLLAQGFCVGIGAGCLFVPCVSVLPTYFSSRLGTALGLAVSGSSMGGVIYPIVLNELIGPLGFGWSVRVIGFIALGTLLVPIAVMKQRVKPPRARALIDWSAFSDIPYMAFTLASLLAFMGLFALLFYISYFGAAKPITDTRMAFYIVPILNAASCFGRTIPNAMADKIGPFNLIAPCCLAVGVLILCLLAVTTEAGLIVIALLSGFFGGALIGLPPLCFVALTKDKTKIGTRIGMGFGMVGLGVLAGGPAGGAILSHSHHSNWTGLWVYGGVTSLVAGFIICIAV
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of the antibiotic 2,4- dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde (DHMBA) and its derivatives (PubMed:23001671).  Is probably involved in the transport of the metabolites to the environment (Probable).
What are the official names of this protein?
MFS-type transporter dbaD, Derivative of benzaldehyde biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREG_MYCMM
Sequence: MAKHSHDHTHDHHDRPRRVRKPGEPLRIGVGGPVGSGKTALVAAICRQLRDELSLAVLTNDIYTTEDADFLRKHAVLPDSRITAVQTGGCPHTAIRDDITANLDAIDDLIAAHDALDLILVESGGDNLTATFSSGLVDVQIFVIDVAGGDKVPRKGGPGVTFSDLLVVNKTDLAPLVGADLKVMARDAEAVRDGRPTVLQSLTEDPAATKVLDWVRSQLAAAG
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UTP25_CHICK
Sequence: MGKRRGGRELARGLSKRQRKHLRQFGEQHPVCDRVSGRPEATQICELSDNSDKSSAESDSETEVEQVSVYHKLLATLKASPESESEEEEDESESEEAGESEAELDSEGSQEPKEAVGGEEEQNDVPEQEEEVAAKDPPEQAFGQEEADGVETSCDPNRGAIEEFTDVKHEAEFSLETNFMEEESGDCDADKRESNSSQAFSEDPFKQHMDKELEEKEVEKISTLSKTSSQSKWPRLGQLTFSSTLEKHTTLKPDKEFSVKQLYLHKPLESTWPKVNKHYLSSASKPSDSFFTPLQRELFCIMNTYRDLFYPERNALTNGEEIRHAYCLHALNHILKANAQVLSNNAKKRDQKPGTDSDDYRDQGLTRPKVLMIVPFRECALRIVHIFISLLEVNEKRKIDVSNKKRFKGEFGSDPDEKPPNLKRPEDYEAVFAGNIDDHFRIGVAILQKSMRLYAPFYSSDIIIASPLGMRTIIGTEGEKKRDFDFLSSIEMLIIDQADIYLMQNWEHVLHLMRHINLLPLDSHGVDFSRVRMPNLNNWSKYYRQTLLFSALQDPQINAIFNKHCFNYVGQVAVRNVPLSGSISRVVVQLPHVFRRIEAENLTSVIDTRFQFFIDKVLPEYRDAIMSHTLIYVPSYFDYVRLRNYFKKEELNFTHICEYTKKAGICRARRSFLKGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYSHFYSEICNMMKATDSGVDATWTCTVLYSKYDAQKLAAVVGIDRTAQMLQSKKNVHLFVTGENE
What is the function of this protein?
Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (By similarity).  Essential for embryonic development in part through the regulation of p53 pathway.  Controls the expansion growth of digestive organs and liver (By similarity).  Also involved in the sympathetic neuronal development (By similarity).  Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53 (By similarity).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25 homolog, Digestive organ expansion factor homolog, UTP25 small subunit processor component.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: APOC4_MOUSE
Sequence: MSLLRCRPRDLPSVSLSVLFLVSFVASMSTESLSPTPGPESSRWSLVRARVLEMVEPLVTRTRDRWQWFWGPGAVQGFMQTYYEDHLKDLGPRTQAWLQSSRDHLLNKTHSLCPRLLCKDRTQG
What is the function of this protein?
May participate in lipoprotein metabolism.
What are the official names of this protein?
Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C2-linked, ACL, Apolipoprotein C4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPA_CUPNH
Sequence: MEFSTKALDWSKAGQNGFLATKTDCLVVGLFEGQNLAGVAKALDVATKGLVGRLVKQGDFEGKRGTQLMLHEVAGVGAARVLLVGLGKEADFSDKAFADAVRTAVRALSSTRAASALWCLAQQAPQQRDVAWAVITTITLVREAGYRLLERHPGLKRANANGKPNGNDKSSLRKVVIAVDTGNARAATQAVVRGTAIANGMELTRDLGNLPSNICTPTYLANTARGIAKRHKLKAEVLGRKQIEALNMGAFLAVTKGSEEPPQFIVLRYDGAGAKQAPVVLVGKGITFDTGGISLKPGEGMDEMKYDMCGAASVLGTIQAVAEMGLKLNVIAVVPTCENMPSGIATKPGDVVTSMSGQTIEILNTDAEGRLILCDALTYVERFKPAAVIDVATLTGACIIALGHINSGLYARSDALADALLQAGRRAMDTAWRMPLDDEYQDQLKSNFADMGNIGGRPAGSVTAACFLSRFTEKYDWAHLDIAGTAWKSGAAKGATGRPVPLLAQFLMDRAA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESPNL_MOUSE
Sequence: MEAQQALVASKDGDMATLERLFEAGALRPDITDDLGAGLVHHATRAGHLDCVKFLVQRAKLPGNQQAHNGATPVHDAAATGNLAELCWLVRDAGCGLQDQDASGVSPLHLAARFGHPALVEWLLREGHAATLETLEGALPLHHAAVSGDLTCLKLLTAAHSSGVNQRTCSGASPLYLACQEGHLHLAQFLVKDCGADVRLRALDGMSSLHAAAAHGHYSLVVWLVTFTDIGLTARDNEGATALHFAARGGHTPILDRLLLMGAPIMRDSWGGTPLHDAAENGHMECCQTLLSHHVDPFLRDEDGYTAIDLAEYHGHQDCAQFLREMSRPVRVLMTPPPPPFPPPPLLAAKLSLEEERRGDSGLKSPSSATLSPVWPAQPVPREPMACTAPLRVTTPDALQGPEVEARDSRAGLATLQLDGLPAGDLDMLVPTQDERGRPIPEWKRQVMVRKLQARLGADHPPEDQDQSQRQDSGPTAAEQATWRYSQTHQAILGPFGELLTEDDLVYLEKQINDLQLRRRCQEYESELGRLAAQLQALLPEPLVSITVNSHFLPRAPGLEDEEAPVLATELEASEEPGKAEPRGQPLPFWCSHIGRLVRSMSLLLKGMNGLAQGEEKPPSPVPQDLGKETIAGPSRSEAQREIQECGVSVRTLRGNFEFAPDLPCALNSGPCELGVRPGQCLRGCWSAPPQPRGDAMGGEPGPGDTEEASDSGISCEEAPSEAGAGPGLDLASLRKERIVMLFLGHWKKSAYTPALRTAACRTLEAQRARSRGPEAAGSPRPSSPQPSDGPRLGHLWQQRGIITHLLGTWKAIMAHVPARQLRRLSRRERGPLSPEQFLPHVDGAPVPYNSLSLDLFMLGYFQLLECDLPAEERKMRHLLCFEVFEHLGAHGWEAVRAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSQGPPWDVEPGRKLGLTPLGSLPHASLPGSGPEPAVPPRLGSDSQGSSFNSGDICGYIDRSFAFWKEKEAEMFNFGE
What is the function of this protein?
Binds to but does not cross-link actin.  Required for the formation and maintenance of inner ear hair cell stereocilia and staircase formation.  Essential for normal hearing.
What are the official names of this protein?
Espin-like protein.
What are the subcellular locations of this protein?
Cell projection, stereocilium.
Protein: CHLB_ARAHE
Sequence: RRLLRDLDIEINQIIPEGGSVEDLKDLPKAWFNLIPYREVGLMTAIYLNKEFGMPYISTAPMGAVDIAEWIRQIHKNVNTLAPSSSSKKVDYEPYIDGQTRFV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex (By similarity).
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: C3H47_ARATH
Sequence: MCSGPKSNLCSSRTLTEIESRQKEEETMLLLEFAACDDLDSFKREVEEKGLDLDESGLWYCRRVGSKKMGLEERTPLMVAAMYGSIKVLTFIVSTGKSDVNRACGEERVTPLHCAVAGCSVNMIEVINVLLDASALVNSVDANGNQPLDVFVRVSRFVASPRRKAVELLLRGGGVGGLIDEAVEEEIKIVSKYPADASLPDINEGVYGSDEFRMYSFKVKPCSRAYSHDWTECAFVHPGENARRRDPRKYPYTCVPCPEFRKGSCPKGDSCEYAHGVFESWLHPAQYKTRLCKDETGCARKVCFFAHKREEMRPVNASTGSAVAQSPFSSLEMMPGLSPLAYSSGVSTPPVSPMANGVPSSPRNGGSWQNRVNTLTPPALQLNGGSRLKSTLSARDIDMEMEMELRLRGFGNNVEETFGSYVSSPSRNSQMGQNMNQHYPSSPVRQPPSQHGFESSAAAAVAVMKARSTAFAKRSLSFKPATQAAPQSNLSDWGSPNGKLEWGMKGEELNKMRRSVSFGIHGNNNNNAARDYRDEPDVSWVNSLVKDSTVVSERSFGMNERVRIMSWAEQMYREKEQTVV
What is the function of this protein?
Involved in salt stress response.  May positively modulate plant tolerance to salt stress.
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 47, AtC3H47, AtSZF1.
Protein: DNLJ_DESHD
Sequence: MSDVSQRIEALREQIEEANYQYYGLDQPTLSDAEYDALLQELIRLEKEHPEFLTPDSPSQRVGGYIAKEFPKVRHAEALLSLDNAFDAGDLLEFDRRVRSMVAEVEYVVELKIDGLTVALTYEDGALVRGATRGDGEVGEEITANLKTIPAIPLRLRKQADRLDVRGEGYMPKGSFLRLNQEREEAGQPLFANPRNAAAGSLRQLDSRITAQRKLGYFAYQVLTPEEGELASQTAVLDYLKEQGFSVNPEYRVFSAIEEVIAYCGEMVEKRHNYPYDIDGLVIKVNDIAQQRELGFTAKSPRWAIAYKFPAEQVETVVEDIVIRVGRTGVLTPTAYLTPVFVAGSTVGRATLHNLDNIRAKDVRIGDHVLIQKAGDVIPEVVKILPEKRTGGERIFEMPELCPECQSPVIREEGEAAHRCTSITCPARQREAIIHFVSRNAMNIDGLGPAVIYQLLEAGLIKDAADLYALEYDALVPLERLGKKSAENLLKAIEDSKERGLAPLIFGLGIRHVGEKAGKILAQKYGTMEDLEKAQVEELQEIPDVGPAMAQSVAQFFQQESTHHFLNKLRQAGVVMSAQHSAKPQIFAGKSIVVTGSLQRWDRHYVETMIEEFGGKAASSVSKKTAFVVAGEKAGSKLAKAKELGIPVLSEEEFAELLP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RISA_CHLPN
Sequence: MFSGIIQELGEVCFFEAQGNGLSLGIKSTPLFVTPLVTGDSVAVDGVCLTLTSCNESKIFFDVIPETLACTTLGEKRCSDQVNLEAALKMGDSIGGHLLSGHVFGTAEIFLIKENRYYFRGSKELSQYLFEKGFIAIDGISLTLVSVDSDTFSVGLIPETLQRTTLGKKREGERVNIEIDMSTKIQVDTVKRILASSGKD
What is the function of this protein?
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
What are the official names of this protein?
Riboflavin synthase, RS.
Protein: ASNA_BACFR
Sequence: MSYLIKPQNYKPLLDLKQTELGIKQIKEFFQLNLSSELRLRRVTAPLFVLKGMGINDDLNGIERPVSFPIKDLGDAQAEVVHSLAKWKRLTLADYHIEPGYGIYTDMNAIRSDEELGNLHSLYVDQWDWERVITAEDRNADFLKEIVNRIYAAMIRTEYMVYEMYPQIKPCLPQKLHFIHSEELRQLYPDMEPKCREHAICKKYGAVFIIGIGCKLSDGKKHDGRAPDYDDYTSKGLNDLPGLNGDLLLWDDVLQRSIELSSMGIRVDKEALLRQVKQENQEQRLELYFHKRLLNDTLPLSIGGGIGQSRLCMFYLRKAHIGEIQASIWPEEMRRECTALNIHLI
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CB23_HORVU
Sequence: MASTIMAAASRAVVAKTPFLSGQGRAASASPLRDIAAATNGRITMGNDLWYGPDRVKYLGPFSAQTPSYLNGEFPGDYGWDTAGLSADPEAFARNRALEVIHGRWAMLGALGCVFPEVLQKWVGVEFKEPVWFKAGSQIFSEGGLDYLGNPNLVHAQSILAVLGFQVLLMGLVEGFRINGLDGVGEGNDLYPGGQYFDPLGLADDPVTFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLENLFDHLDDPVANNAWVFATKFAPGS
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein of LHCII type III, chloroplastic, CAB.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: GP_TSWVR
Sequence: MRILKLLELVVKVSLFTIALSSVLLAFLIFRATDAKVEIIRGDHPEVYDDSAENEVPTAASIQRKAILETLTNLMLESQTPGTRQIREEESTIPIFAESTTQKIISVSDLPNNCLNASSLKCEIKGISTYNVYYQVENNDVIYSCVSDSAEGLEKCDNSLNLPKRFSKVPVIPITKLDNKRHFSVGTKFFISESLTQDNYPITYNSYPTNGTVSLQTVKLSGDCKITKSNFANPYTVSITSPEKIMGYLIKKPGENVEHKVISFSGSASITFTEEMLDGEHNLLCGDKSAKIPKTNKRVRDCIIKYSKSIYKQTACINFSWIRLILIALLIYFPIRWLVNKTTKPLFLWYDLIGLITYPILLLINCLWKYFPFKCSNRGNLCIITHKCTKLCICNKSKASKEHSLECPILSKETDHGYNKHKWTSMEWFHLIVNTKLSFSLLKFVTEILIGLIILSQMPMSMAQTTQCLSGCFYVPGCPFLVTSKFEKCPERDQCYCNVKEDKIIESIFGTNIIIEGPNDCIENQNCAANPSIDNLIKCRLGCEYLDLFRNKPLYNGFSDYTGSSLGLTSIGLYEAKRLRNGIIDSYNRTDKISGMIAGDSLNKNETSIPENILPRQSLIFDSVVDGKYRYMIEQSLLGGGGTIFMLNDKTSETAKKFVIYIKSVGIHYEVSEKYTTAPIQSTHTDFYSTCTGNCDTCRKNQALTGFQDFCITPTSYWGCEEAWCFAINEGATCGFCRNIYDMDKSYRIYSVLKSTIVADVCISGILGGQCSRITEEVPYENALFQADIQADLHNDGITIGELIAHGPDSHIYSGNIANLNDPVKMFGHPQLTRDGVPIFTKKTLEGDDMSWDCAAIGKKSITIKTCGYDTYRFRSGLEQISDIPVSFKDFSSFFLEKAFSLGKLKIVVDLPSDLFKVAPKKPSITSTSLNCNGCLLCGQGLSCILEFFSDLTFSTAISIDACSLSTYQLAVKKGSNKYNITMFCSANPDKKKMTLYPEGNPDISVEVLVNNVIVEEPENIIDQNDEYAHEEQQYNSDSSAWGFWDYIKSPFNFIASYFGSFFDTIRVILLIAFIFLVIYFCSILTTICKGYVKNESYKSRSKIEDDDDSEIKAPMLMKDTMTRRRPPMDFSHLV
What is the function of this protein?
Forms the spikes present at the surface of the virion together with Glycoprotein N.  They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity).  Probable class II fusion protein (Probable).
What are the official names of this protein?
Envelopment polyprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the tospovirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein N]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Glycoprotein C alone is retained in the membrane of the endoplasmic reticulum, but not transported to the Golgi. Coexpression of Glycoprotein C and Glycoprotein N results in efficient transport of Glycoprotein C to the Golgi complex, indicating that their interaction is essential for proper targeting to this organelle, where virion budding occurs. SUBCELLULAR LOCATION: [Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=Glycoprotein G2 is retained in the Golgi complex and probably contains a Golgi retention signal.