PharMolix/UniProtQA huggingface dataset:
Protein: UTH1_YEAS6
Sequence: MKLSALLALSASTAVLAAPAVHHSDNHHHNDKRAVVTVTQYVNADGTVVIPAANTATSAAADGKVESVAAATTTLSSTAAAATTSAAASSSSSSSSSSSSVGSGDFEDGTISCSDFPSGQGAVSLDWLGLGGWASIMDMNGNTATSCQDGYYCSYACSPGYAKTQWPSEQPSDGRSVGGLYCKNGKLYRSNTDTNSLCVEGQGSAQAVNKVSGSIAICGTDYPGSENMVVPTVVGAGSSQPINVIKEDSYYQWQGKKTSAQYYVNNAGVSVEDGCIWGTEGSGVGNWAPVVLGAGYTDGITYLSIIPNPNNKEAPNFNIKIVATDGSTVNGACSYENGVYSGSGSDGCTVSVTSGSANFVFY
What is the function of this protein?
Involved in aging, oxidative stress response, and in the regulation of mitochondrial biogenesis.  Inactivation of UTH1 increases life span, leads to higher resistance to heat stress and to hydrogen peroxide, and increases sensitivity to the superoxide radical-generating drug paraquat and to copper.  Also required for the selective autophagic degradation of mitochondria (mitophagy) in response to nitrogen starvation.  May play a role in cell wall morphogenesis and septation.  Involved in the remodeling of the cell wall during the various phases of yeast culture development and under various environmental conditions and plays a role in septation.  Involved in cell sensitivity to boric acid (By similarity).
What are the official names of this protein?
Probable secreted beta-glucosidase UTH1, Youth protein 1.
What is the protein family that this protein belongs to?
Belongs to the SUN family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein. Secreted, cell wall. Note=Non-covalently bound to the cell wall.
Protein: YEAD_SCHPO
Sequence: MRGIVTRIVLSTQKCLPSVNCTRRYYSKQKDISIVRQRLGRPGNHLKIGIVGMPNIGKSTLFQILTKTNLGNPANYPFATIDPVHAKAPVLDSQYELLCEIYQPKTRIPAQLTIYDTAGLTRNSSKGEGLGNAFLSNIRSVDALFQLVRAFPEAQVPHVEKSVDPVRDLQIIQEELLLKDAEFLESYLKKEGRSPKTCAKALDTARRALEVVLGKGRQISKAEWNDEQIPILNSLNLLTAKPVVYLVNMDQDDYLSDEQEALKGIKEWVEKNSFGDQVIPLSVLFEEQLFMLTPEEAAQECASLGKNSQLSEIICAGYSALNLIHYFTASEKIVQAWTIADGSKAPDAAGIIHSDFKKKFVAGEVIKFSDFEKYKSVDACKSVGKCKTKGKDYTVEPGDIIFWKIAR
What is the function of this protein?
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency.  Has lower affinity for GTP (By similarity).
What are the official names of this protein?
Obg-like ATPase homolog, OLA1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
Protein: PROFK_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-1, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: UREG_MARMS
Sequence: MKKQTLRIGVGGPVGSGKTALLRSLCSAMRDYYNIAVVTNDIYTQEDAKFLTQHEALDADRILGVETGGCPHTAIREDASMNLAAIDQLLERHGALDVVFVESGGDNLSATFSPELSDFTIYVIDVSAGDKIPRKGGPGITKSDLLIINKTDLAPLVGASLDVMAHDAKIQRGDRPFIFSNLKSAQGLDEIIQIIVSEGMLEAKEIPAAKAVV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_CORJK
Sequence: MSEVSEVRVRFCPSPTGTPHVGMVRTALFNWAYARHTGGKLVFRIEDTDAKRDSEESYQAIIDSLKWLNLGWDEGIEVGGPHEPYRQSQRMDIYADVLEKLKESGDVYPAYSTNEEVQARHKAAGRDPQLGYDNYDRDLTEEQIAQFKAEGREPVWRLRMPDNRIYEWHDLVRGDMSVDGKTVPDFVVARSNGQPLYTLVNPVDDALMEITHVLRGEDLLPSTPRQIALYEALVRVGVAKQVPTFGHLPFVMGEGNKKLSKRDPESNLFNHRDNGIIPEGMLNYLSLLGWSLSADEDIFTMQQLIDNFDVADVKPNPARFDQKKLEAINADHIRMLELGDFTERLRAYLEEYKGFPADYPADKFAFAAELVQTRIKTLSDADGLLRFLITSDADLSLDEKAARKNLKEDAVEVLEVAIAQLEAIADGEFKTDVIEKALQSKLIEEMELKPRKAYGALRVAISGAAVSPPLFESMELLGKESTLARLRAAREQTPFAPAQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_SYNS9
Sequence: MTVKDFIDKLLGRQTSSASTAKQRLQLVLAHDRSDLNPELLAQMRREILEVVARYVEIDIEEGDVSLETEDRMTALVANLPIRRSIQQSPNGGTL
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: LEPA_MACCJ
Sequence: MNNEQRLKRQERIRNFSIIAHIDHGKSTLADRILENTKSVATREMKAQLLDSMDLERERGITIKLNAVQLNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELIPVINKIDLPAAEPERVRQEIEDVIGLDASDAVLASAKANIGIEDILEQIVELVPPPMGDPEAPLKALIFDSAFDAYRGVISSIRIIDGTVKAGDKIKMMATGKEFEVVEVGINTPKQMPVAELTVGDVGYLTASIKNVGDSRVGDTITHASNPASEPLQGYKKMNPMVFCGVYPIDTGKYNDLREALEKLQLNDASLEFEPETSQALGFGFRVGFLGLLHMEIIQERIEREFGIELIATAPSVIYKCEMTDGSEVVVDNPSKMPDPQKIDKIYEPYVKASIMVPNDYVGAVMELCQKKRGNFQTMDYLDDIRVNIIYEVPLSEVVFDFFDQLKSSTKGYASFDYELIGYQESKLVKMDILLNGETVDALSFIVHRDFAYDRGKVIVEKLKTLIPRQQFEVPVQAAIGQKIIARTNIKSIGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKSVGSVEIPQDAFLAVLKMDEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS4B_NITEU
Sequence: MSRFTGPRLKIMRALGVDLPGLSRKTIASRPTPPGQHGAKLVRRRKSDFGIKLQEKQKLRFNYGLSERQLRHLMLNARKSTEPTGETLLQLLERRLDNVVFRAGFAPTVIAARQLVSHRHVRLNGKPVNIPSIRLNVGDEITIKPESLNLPIVLGTLQDLPLSRPEWLLWDEKDKTGKITHLPTAEDVPFPIDVQQVVEYYANRM
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4 B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RS10_ERWT9
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PETL_WELMI
Sequence: MVILISYFCFLLVFFLFTLILFIGFNRIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SP2B_BACSU
Sequence: MKKRKNKKNSKAAEKALKVTINGKEETVYEQETPETEANKSMTFSNWEEKRQAEQEVAASQEHPDEDEFNWDSEEDKVFKEDPKVVPPFQKKKTKLYAKGKTGAAKPVKRVAATIAFAAVIGTGLGLFALNISGNKEASAPASLEDSLGSQTAKAGDTSADKQTSGAEKQAAQTEGTYKTYAVQAGKFSNEKGAETLTEQLTEKGYSAVSLSKDDGYTYVIAGLASEKEVSQQLGQVLIDSDFEAWGGKELSLSIESDMTDSFKETAELAAKAILDEDITKASVEKIEKSLGETKASETGEKKAILQALKELEDPSAEAGWKAQQELLAVVK
What is the function of this protein?
Involved in endospore development.
What are the official names of this protein?
Stage II sporulation protein B.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y1945_MYCTO
Sequence: MRSDTREEISAALDAYHASLSRVLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACEEELGGTLRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTATAAAQREGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRPDHLHGLATQLMDWLHPDGNFSDQERARKRGITMGKQEFDGMSRISGLLTPELRATIEAVLAKLAAPGACNPDDQTPVVDDTPDADAVRRDTRSQAQRHHDGLLAGLRGLLASGELGQHRGLPVTVVVSTTLKELEAATGKGVTGGGSRVPMSDLIRMASNAHHYLALFDGAKPLALYHTKRLASPAQRIMLYAKDRGCSRPGCDAPAYHSEVHHVTPWTTTHRTDINDLTLACGPDNRLVEKGWKTRKNAKGDTEWLPPAHLDHGQPRINRYHHPEKILCEPDDDEPH
What are the official names of this protein?
Uncharacterized protein MT1995.
What is the protein family that this protein belongs to?
Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.
Protein: YZ34_AQUAE
Sequence: MLEVEKKIKQKLGIDETEVLSSLTSYRKKGKTYYKIVTYDSKTKQSRRYHVPRMFEEEILALWKQRQKYIEEERELEREVKSLLKKYGDAEKIKEILEKVAGESFDKAVSSYAIKTYTNKAKELFKSFKEDLIKLYREGVLKRLSVLQVLYLLANLKEISEDTERGSYFFKKGLNTIIKVAKNERIPNPFGTLKNDFFLSGKQTPYDFLLSNFLEELIGETLGELLEKEIEKLVAEEKAKEIEGKVKKLKEIVSWFETLPYEIKQIAKEVISDNVLDIAEKFYKDMKECNYSLDEAKAFLTSSPRDNLVNYMQYLKSI
What are the official names of this protein?
Uncharacterized protein aq_aa34.
What is the protein family that this protein belongs to?
To A.aeolicus AA07 and AA11.
Protein: LDH1_LISMO
Sequence: MKDHQKIILVGDGAVGSSYAFACVNLSIGQEFGIIDIDKDRTIGDAMDLSHAVPFSTPKKIYSANYSDCHDADLVVVTAGTAQKPGETRLDLVNRNIKIMKGIVDEVMASGFDGIFLIASNPVDILTYATWKFSGLPKERVIGSGTSLDTARFRMSIADYLKVDARNVHGYILGEHGDTEFPAWSHTTVGGLPITEWISEDEQGAMDTIFVSVRDAAYEIINKKGATFYGVAAALARITKAILNNENAILPLSVYLDGHYGMNDIYIGAPAVVNRQGVRHIVEMNLNDKEKEQMKNSADTLKKVLDDAMKQID
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_FLAJ1
Sequence: MKILIINSGSSSIKYQLMVMPANEVICSGMIDRIGLETSNITFKTVSNSFEEILPVPTHKVGLQKVADMLLDAETGVIKTTSEITAVGHRVVHGGSYFSNTTVITEEVKEKIKELSELAPLHNPAHLVGINVAEEIFASAKQVAVFDTAFHQTIPVEAHKYAIPNFLLTEHKVRVYGFHGTSHKYVSEKAINYLEKGSKIITIHLGNGCSMTAVKDGKSIDTTMGFSPANGLVMGTRAGDIDQSVIFYMVKSLGYTPDEVNSILLKQSGMLGLTGYSDLRDIESKASEGNKDCQLALLMNAYRIRKTIGSYAAALNGLDAIVFTAGIGENSSFMRNLICTDMDYFGIEIDKEKNQIRSKELREINTPNSIVKILVVPTDEEFEIANQVYQLLEN
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGX31_CENNO
Sequence: GRDSCVNKSRCAKYGYYSQCEVCCKKAGHKGGTCDFFKCKCKV
What is the function of this protein?
Blocks Kv11/ERG potassium channels (tested in MMQ lactotroph cells that contain the three ERG channels: rKv11. 1/KCNH2/ERG1, rKv11. 2/KCNH6/ERG2 and rKv11. 3/KCNH7/ERG3).  This toxin can be used to distinguish slow deactivating components (ERGS) from fast deactivating components (ERGF) currents, since it specifically blocks ERGS.
What are the official names of this protein?
Potassium channel toxin gamma-KTx 3.1, CnErgTx2, CnErg2, Ergtoxin-2, ErgTx2, Ergtoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the ergtoxin family. Gamma-KTx 3 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLTP_PIG
Sequence: MALLAEHLLRPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPTKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEECLEKVRLFLVNYTATIDVIYEMYTRMNAELNYKV
What is the function of this protein?
Accelerates the intermembrane transfer of various glycolipids.  Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids.  May be involved in the intracellular translocation of glucosylceramides (By similarity).
What are the official names of this protein?
Glycolipid transfer protein, GLTP.
What is the protein family that this protein belongs to?
Belongs to the GLTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MECA1_BACCR
Sequence: MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAELSKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQTGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELYSFEDRYYVYVEFDEVLHDEEEIDRILSIILEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.  Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease.  When overexpressed, inhibits sporulation.  Also involved in Spx degradation by ClpC (By similarity).
What are the official names of this protein?
Adapter protein MecA 1.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: PUR5_JANSC
Sequence: MTDSKPDALTYADAGVDIDAGNALVDRIKPAAAATNRAGVMAGLGGFGALFDLKAAGYDDPVLVAATDGVGTKLKIAIDTGNFDTIGVDLVAMCVNDLVCQGAEPLFFLDYFATGKLDVDDAARIVEGIAAGCKASGCALIGGETAEMPGMYAPGDFDLAGFSVGAMERGRALPDGVAEGDVLLGLASDGVHSNGYSLVRRVVERSGLAWDAPAPFAQSSLGEALLAPTRLYVQPALAAIRAGGVHALAHITGGGLTENIPRVLPDGLGVDIDLSSWSLPPVFGWLAQEGALDQAELLKTFNAGLGMVLVVSADAVDGLTWTLEDAGESVHRIGTVTAGAGVRYSGSLG
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTM1_MAGO7
Sequence: MNATTEQEAIVKVLFTTTEQGLELPESKRLLLVPADIRRYGLSRVLNSESMLNTAAPIPFDFLVNGTFLRTTLEDYLKENGLPFEKTVTLQYVRSLVPPAYEASFEHDDWVSSVDLLSATSSAGKWSGSSFLQGQDRILSASYDGLLRIWNGSGQALATSSVVNRGPLCGLKSAKFMSSTKIAAAGLDRTVRIWDYTEADDHFSGQLKPTLELYGHRSIIESLGVDGSSRRILTACADGSIGLWTTSKKLAPEAPTALLPQTYATKRRKGSTTSANIIAQRGALSLIPVHSRPVSAAIFDPQNQHTAYSASQDHTLKVLDLTTSRVVSTITTSNALMSACYLSNKSAPLIAAGTSSRNVTLIDPRESAAATSVMTLRGHINVVSSVSASPDNEYSLVSGSHDGTCRIWDLRSVRPAAGKEETGLGSVGESVYLIERESLGDKKRPLAGEGVKVFDVQWDKTWGIVSGGEDKKVQINKGRNIISS
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein YTM1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: RECF_MAGMM
Sequence: MQLDRLTLRDFRNITEAELRFGPGLNLITGPNGHGKSNLLEAIGLLATGRSFRRAPAAALRRYGQPWFHLRGETTARDLGHRLEFFGQAGRQAVKINGKSASAASALGQALAAVIVTPDTLRLVQDGPGVRRGFVDWVAFTCGRQQGALSHAVVAGDYQKALKARNRLLKLPRVEAGEWLAWESQLATLGAKMARNRYQVLQRLQPHLDRMLEDLGMAQRLTITLSCQLDRHGTHWAEDESAAASLYRRLLAENRASERRSGGTAIGPHRDDLVLRLDGHALAQFGSQGQQKRAALALKLAEAQLLQEQLGEWPLFVLDDPAAELDTDGMSRLMGLLARCGGQIFVASCRAQTIPWSGLAPQRFYVDQGVFALTEEIPLESL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_BORBZ
Sequence: MLLEKLNSATSKIKLIEEKLQDINLIKDQKKYSKIIKEYTYLEKINTKKIEYEKILSQINDTKTILEKEDQQEMKELIKQELIDLDKKKEDLEHQIKILLLPQDENDSKNIIIEIRAGTGGEEAALFANNLYSMYIKYSEKKKWKTEIINFNETELGGFKEIIFEIKGKDVFKKLKYESGVHRVQRIPITESNGRLQTSAATVAVLPNIEETEIDINEKDLRIDVYRSSGAGGQHVNTTDSAVRITHLPTGIVVQCQNERSQHKNKDQAMKILRARLYEFEDSKKQEQRSSNRKQQVGSGDRSERIRTYNFPQNRITDHRANITLYKLEEFMQGELDPLLDPLMIALQEQELKSNSI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_SALPK
Sequence: MNKVVLLCRPGFEKECAAEITDKAGKREIFGFARVKENAGYVIYECYQPEDGEKLISELPFSSLIFARQWFVVGELLQHLPPEDRITPVVGMLQGVVEKGGELRVEVADTNESKELMKFCRKFTVPLRAALRDAGVLTNYETPKRPVVHVFFIAPGCCYTGYSFAHNNSPFYMGIPRLKFPSDAPSRSTLKLEEALHVFIPEDEWDERLANGMYAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRYRPNRNNISWMVCDMVEKPAKVTALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGVNAQIQARQLYHDREEVTVHVRRLWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QDR2_CANAL
Sequence: MLSTTQSVTEPTEVTSKKVEDIEKENDEETPYSIFTSYDRLVLIVILSLIGFWSTISSPIYFPALPTLTSYFHTSSSIMNISVVAYLIFQGIAPTISSNLADTFGRRPVILASIIVFCASCVAISQTNVYWLLAVLRCIQAAGIAAVISISSGVAGDVCTRANRGSMVGAVAGLQLVGNGIGGLVGAALISSFNSWRSIFIFLTIGGGVTFILAIFILPETSRKLVGNGSVVPKNILNKSPYIYLPHFKKRMNNDITTIVPATRFDLLGPLKIFFQKNVFCTLLPVGIHFAAWTMVLTSLSTELESRYHYSVMHVGLIYLPQGIACIAGSLVVGKSLDWYYRYRKTIYDQEVECLPLDERPQFNIVATRLTLSVVPALLMIIGLVIFGWCIQYKRHIISIIISTILVSFSASVFIAICTTMLVDLYPNNGSGSTSCLNLMRCWLAALGAGVLDSMINAMNVGGTYTVVAGFCILFDLALIYVLHNAKKKFSNSGPTTTKSPPKQ
What is the function of this protein?
MFS antiporter that does not display functional linkage as drug transporter and performs functions that significantly affect biofilm development and virulence.  No substrate for transport has been identified yet, but plays an important role in the growth in the host.
What are the official names of this protein?
MFS antiporter QDR2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
Protein: KCY_VIBPA
Sequence: MSSQTPVVTVDGPSGAGKGTLCMLLAKKLGFQLLDSGAIYRVLALAAIHHGVDTESEDALVPLATHLDVQFIAEGDLVKVILEGEDVSGELRKEETGMAASKVAALPRVREALLRRQRAFEAAPGLVADGRDMGTVVFPSAQAKIFLDASAEERANRRLKQLQDKGLDVRFADLLSEIQERDDRDRNRPVAPLRPAEDALVLDSTSMTIDEVVEKALQYIESKLAE
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_YERPY
Sequence: MMQSKPGVLMVNLGTPDAPTSKAIKRYLAEFLSDRRVVDTSPLLWWPLLHGVILPLRSPRVAKLYQSVWMEEGSPLLVYSRRQQKALAARMPDIPVELGMSYGSPNLPEAIEKLLAQGVTNLVILPLYPQYSCSTSAAVWDAVARVLKGYRRLPSISFIRDYAEHPAYISALKQSVERSFAEHGQPDRLVMSFHGIPKRYAQLGDDYPIRCEDTSRALRAALPLPAEKIIMTYQSRFGREPWLTPYTDETLKSLPSQGVKHIQLICPGFSADCLETLEEIKEQNREFFLHAGGEKFEYIPALNDDEGHIALLEQLIRHNI
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMH3_SCHPO
Sequence: MGIPKSSIYFCILLFCIISFYLQSSKDGPKELKVKYVFLKKATAKQRGESSLTDSDYFPKQPNMNATLFMLCRNRDIKDALVSIQSVEDRFNHRYHYPWTFMNDAPFTKEFITATSKMVSGDATYVQLNNEEWGIPINIDLNRMLKSIRDMTDDKVIYGFSLSYRIMCRFNSGFFYRNKALSHYDYYWRVEPGVEYSCDIPYDPFRKLSDENKAYGFVISMTDYYETLPSLWNVTRDFIHQNPQYLAQNNSLDFIVNDHQGLSGDYNLCHFWSNFEIANLNFFRSPAYTDYFAHLDKNYGFFYERWGDAPVHSLAASLFLNKSQIHYFEDFGYYHLPWYHCPTDVQSHATARCLCDPTGTIDYLPFSCAIKWLENINS
What is the function of this protein?
Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins.
What are the official names of this protein?
O-glycoside alpha-1,2-mannosyltransferase homolog 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 15 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: RNF43_HUMAN
Sequence: MSGGHQLQLAALWPWLLMATLQAGFGRTGLVLAAAVESERSAEQKAIIRVIPLKMDPTGKLNLTLEGVFAGVAEITPAEGKLMQSHPLYLCNASDDDNLEPGFISIVKLESPRRAPRPCLSLASKARMAGERGASAVLFDITEDRAAAEQLQQPLGLTWPVVLIWGNDAEKLMEFVYKNQKAHVRIELKEPPAWPDYDVWILMTVVGTIFVIILASVLRIRCRPRHSRPDPLQQRTAWAISQLATRRYQASCRQARGEWPDSGSSCSSAPVCAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLCMFNITEGDSFSQSLGPSRSYQEPGRRLHLIRQHPGHAHYHLPAAYLLGPSRSAVARPPRPGPFLPSQEPGMGPRHHRFPRAAHPRAPGEQQRLAGAQHPYAQGWGLSHLQSTSQHPAACPVPLRRARPPDSSGSGESYCTERSGYLADGPASDSSSGPCHGSSSDSVVNCTDISLQGVHGSSSTFCSSLSSDFDPLVYCSPKGDPQRVDMQPSVTSRPRSLDSVVPTGETQVSSHVHYHRHRHHHYKKRFQWHGRKPGPETGVPQSRPPIPRTQPQPEPPSPDQQVTRSNSAAPSGRLSNPQCPRALPEPAPGPVDASSICPSTSSLFNLQKSSLSARHPQRKRRGGPSEPTPGSRPQDATVHPACQIFPHYTPSVAYPWSPEAHPLICGPPGLDKRLLPETPGPCYSNSQPVWLCLTPRQPLEPHPPGEGPSEWSSDTAEGRPCPYPHCQVLSAQPGSEEELEELCEQAV
What is the function of this protein?
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled.  Acts on both canonical and non-canonical Wnt signaling pathway (PubMed:18313049, PubMed:22575959, PubMed:22895187).  Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF43, RING finger protein 43, RING-type E3 ubiquitin transferase RNF43.
What is the protein family that this protein belongs to?
Belongs to the ZNRF3 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus envelope. Note=According to a report, may be secreted.
Protein: RL31_DINSH
Sequence: MKKDIHPEYHIIDVKMTDGTVIQMRSTWGAEGDQLSLDIDPSVHPAWTGGTSRLLDTGGRVSKFKKKYEGLGF
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.