PharMolix/UniProtQA huggingface dataset:
Protein: Y1395_MYCTO
Sequence: MGHLPPPAEVRHPVYATRVLCEVANERGVPTADVLAGTAIEPADLDDPDAVVGALDEITAVRRLLARLPDDAGIGIDVGSRFALTHFGLFGFAVMSCGTLRELLTIAMRYFALTTMHVDITLFETADDCLVELDASHLPADVRGFFIERDIAGIIATTTSFALPLAAKYADQVSAELAVDAELLRPLLELVPVHDVAFGRAHNRVHFPRAMFDEPLPQADRHTLEMCIAQCDVLMQRNERRRGITALVRSKLFRDSGLFPTFTDVAGELDMHPRTLRRRLAEEGTSFRALLGEARSTVAVDLLRNVGLTVQQVSTRLGYTEVSTFSHAFKRWYGVAPSEYSRRG
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MT1440.
Protein: FIG02_BOARA
Sequence: MAFLKKSLFLVLFLGIVSLSVCEEEKREGEEKEEKREEEEGKEENEDGNEEHKEKRFLGAILKIGHALAKTVLPMVTNAFKPKQ
What is the function of this protein?
Antimicrobial peptide that displays antibacterial, antiprotozoal, and antiviral activity (PubMed:32443921).  Exhibits antibacterial activity against the Gram-positive bacteria S. epidermidis ATCC 12228 (MIC=4 uM), E. casseliflavus ATCC 700327 (MIC=4 uM), S. aureus ATCC 25923 (MIC=8 uM) and E. faecalis ATCC 29212 (MIC=8 uM), and the Gram-negative bacteria E. coli ATCC 25922 (MIC=8 uM), K. pneumoniae ATCC 13883 (MIC=8 uM), the multi-resistant clinical isolate strain K. pneumoniae carbapanemase (KPC) MR (MIC=16 uM), and P. aeruginosa ATCC 27853 (MIC=32 uM) (PubMed:32443921).  Displays antiprotozoal activity against the epimastigote form of T. cruzi (IC(50)=6. 32 uM) (PubMed:32443921).  Does not show antimicrobial against the fungi C. albicans ATCC 90028 and C. parapsilosis ATCC 22019 (PubMed:32443921).  Displays antiviral activity against the human viruses chikungunya (EC(50)=17. 9 uM), Dengue serotype 4 (EC(50)=20. 8 uM) and Yellow Fever (EC(50)=21. 8 uM) (PubMed:32443921).  Shows moderate cytolytic activity against human erythrocytes (HC(50)=48. 9 uM), and activates the oxidative burst in human neutrophils (PubMed:32443921).  Also displays anti-proliferative effects against MCF-7 breast cancer cells (IC(50)=15. 3 uM) and B16F10 murine melanoma cells (IC(50)=12. 8 uM) (PubMed:32443921).
What are the official names of this protein?
Figainin 2, Br22.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CDKC_CONVX
Sequence: DLRQCTRNAPGSTWGRCCLNPMCGNFCCPRSGCTCAYNWRRGIYCSC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes.  VxXXA and VxXXB inhibit alpha-7/CHRNA7 and alpha-3-beta-2/CHRNA3-CHRNB2 nAChR more efficiently than VxXXC.  VxXXB is the most effective at inhibiting alpha-4-beta-2/CHRNA4-CHRNB2 nAChR, followed by VxXXC and VxXXA.
What are the official names of this protein?
Alpha-conotoxin VxXXC, VxXIIC.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBL_SOLTU
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GDS1B_XENLA
Sequence: MDNLNDALEKLKLTGTECTSDKLDGCLDCLLQALGHNNTESSEKIQQSGILQLFASILNSQSSCASKVAHIVAEIAKNELMRIPCVEADLIPPLVQLLHSKDQEVLLQTGRALGNICYDNHEGRRTVDQEGGAQIVVDHLRSRCTLTDPSSEKLMTVFCGMLMNYSSENDSLQTQLIQMGVIPILVDLLAVHSQNTALTEMCLVAFGNLAELESSKEQFAATNVAEVIVKLFKKQTEHEKREVIFEVLAPLAENDAIKMQLVEAGLVECLLDIVQQTVNSEKDDDVAELKTSSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWLPSNNHQLQLAGALAIANFARNDGNCIHMVDSEIVQKLLDLLDRHVEDGNVTVQHAALSALRNLAIPVVNKAKMLSAGVTEEVLKFLPSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNEKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKDVIRTTVQSGGIKHLVTMATSEHVIMQNEALVALGLIAALELQAAERDLESAKLVEVLHRLLSDERSAPEIKYNSMVLICAVMGSEPLHKEVQKLAFLDVVSKLRSHENKTVAQQASLTEQKFTVQS
What is the function of this protein?
Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.
What are the official names of this protein?
Rap1 GTPase-GDP dissociation stimulator 1-B, Rap1gds1-B protein, RalB-binding protein B, XsmgGDS-B, smgGDS-B.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum. Mitochondrion.
Protein: ABCG5_RAT
Sequence: MSELPFLSPEGARGPHNNRGSQSSLEEGSVTGSEARHSLGVLNVSFSVSNRVGPWWNIKSCQQKWDRKILKDVSLYIESGQTMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVFVNGCELRRDQFQDCVSYLLQSDVFLSSLTVRETLRYTAMLALRSSSADFYDKKVEAVLTELSLSHVADQMIGNYNFGGISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANHIVLLLVELARRNRIVIVTIHQPRSELFHHFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFYMDLTSVDTQSREREIETYKRVQMLESAFRQSDICHKILENIERTRHLKTLPMVPFKTKNPPGMFCKLGVLLRRVTRNLMRNKQVVIMRLVQNLIMGLFLIFYLLRVQNNMLKGAVQDRVGLLYQLVGATPYTGMLNAVNLFPMLRAVSDQESQDGLYQKWQMLLAYVLHALPFSIVATVIFSSVCYWTLGLYPEVARFGYFSAALLAPHLIGEFLTLVLLGMVQNPNIVNSIVALLSISGLLIGSGFIRNIEEMPIPLKILGYFTFQKYCCEILVVNEFYGLNFTCGGSNTSVPNNPMCSMTQGIQFIEKTCPGATSRFTTNFLILYSFIPTLVILGMVVFKVRDYLISR
What is the function of this protein?
ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane.  Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.  Required for normal sterol homeostasis.  The heterodimer with ABCG8 has ATPase activity.
What are the official names of this protein?
ATP-binding cassette sub-family G member 5, Sterolin-1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Protein: GVPC_PLAAG
Sequence: ALKDKNQLDRIGIVQGVILXQQIVITAL
What is the function of this protein?
May confer stability to the gas vesicle membranes.  Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.
What are the official names of this protein?
Gas vesicle protein C.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type C family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Binds to the external surface of the gas vesicle membrane.
Protein: NAPA_ECO81
Sequence: MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLLRMKNGKYDKEGEFTPITWDQAFDVMEDKFKTALKEKGPESIGMFGSGQWTIWEGYAASKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYIIQNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVAEYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPSGTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVSDPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFSRRFKTEEVWPEELLAKKPELRGKTLYDVLYATPEVSKFPVSELAEDQLNDESRELGFYLQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGEGYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRAFPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAAQLVNKLTLDATDPLSKETDFKKCAVKLEKV
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL333_STRPF
Sequence: MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVTFTEVK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: LOLA_NITMU
Sequence: MKLSEKFCVFLFFLLFTSTTHATGIGSLKSFMENARTVRADFAQTVLDKSRHIVQTASGAMQFERPGKFRWIYEKPYEQLIVGDGERIWFYDHDLAQVTVRKLDAAIGSSPAALLAGNNDIEKNFHLLEIGLQGNIEWVEATPKTRESTFERVLLGFTLEGILRVMELHDNFGQVTVFEFSGVEQNRKLPPELFKFSPPAGVDVISE
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MSI1H_MOUSE
Sequence: METDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERSPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSHPWTMAPPPGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH
What is the function of this protein?
RNA binding protein that regulates the expression of target mRNAs at the translation level.  Regulates expression of the NOTCH1 antagonist NUMB.  Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'.  May play a role in the proliferation and maintenance of stem cells in the central nervous system.
What are the official names of this protein?
RNA-binding protein Musashi homolog 1, Musashi-1.
What is the protein family that this protein belongs to?
Belongs to the Musashi family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1934_ORYSJ
Sequence: MDSSSCLVDDTNSGGSSTDKLRALAAAAAETAPLERMGSGASAVVDAAEPGAEADSGSGGRVCGGGGGGAGGAGGKLPSSKFKGVVPQPNGRWGAQIYERHQRVWLGTFAGEDDAARAYDVAAQRFRGRDAVTNFRPLAEADPDAAAELRFLATRSKAEVVDMLRKHTYFDELAQSKRTFAASTPSAATTTASLSNGHLSSPRSPFAPAAARDHLFDKTVTPSDVGKLNRLVIPKQHAEKHFPLQLPSAGGESKGVLLNFEDAAGKVWRFRYSYWNSSQSYVLTKGWSRFVKEKGLHAGDVVGFYRSAASAGDDGKLFIDCKLVRSTGAALASPADQPAPSPVKAVRLFGVDLLTAPAPVEQMAGCKRARDLAATTPPQAAAFKKQCIELALV
What are the official names of this protein?
AP2/ERF and B3 domain-containing protein Os01g0693400.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYFA_PASMU
Sequence: MQNLEQITEQALDAIARAEDGKALDAIRVEYFGKKGPFTALMQGLRDVSPEARPAVGQKINDAKQLAQNALNEKKVQLETAELNAQLAKEKIDVSLPGRKVETGGLHPVTMTIDRVTKFFSELGFSVESGPEIESDYYNFDALNIPKHHPARADHDTFWFNPELLLRTQTSGVQIRTMEKMQPPIRIMAPGRVYRNDYDQTHTPMFHQIELLYVDKKANFTELKGLLHDFLRAFFEEDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPNEYAGFAVGMGVERLTMLRYNVTDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_METST
Sequence: MRNIKIEKAVQRPIEQNEIEVVERKGIGHPDSISDGIAEAVSRVLSQTYKEKAGHVLHHNTDEVQITAGESDPKFGGGQIIKPIQILLTGRAANEFTLPSGETKKIGVDTIAIEAAKKFLQDTIINLDVEYGTVVECKIGQGSADLRDVFQRPNTIPSSNDTSFGVGYAPFSQTENLVLKTEELLNSKDFKKQYPFVGEDIKVMGLREKEDITLTIAAAFVSKYVDDVDAYLNMKDELKNIVNDLAAKETDLSVKTLINTADDETKKDESGYYLTVTGTSAEMGDDGSVGRGNRANGLITPNRPMSMEATSGKNPINHVGKIYNLLSNEITREVVSDVEGVKSIDMIILSQIGKPIDQPRTATAHIQTEEGYSINDVEEDVTRIINKWLENITDIKEFMLEGKLRTF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: GLMM_XANOP
Sequence: MSARKYFGTDGIRGRVGQGVISADFVLRLGNALGRVLTQIRGKRPLVLIGKDTRISGYMFEAALEAGLVAAGADVQLIGPMPTPAIAFLTSTLRADAGVVISASHNPHYDNGIKFFSAEGEKLDDATEAAIEAALDAPFHTVESERLGKAIRTRDAIGRYIEFCKASVARGFTLKWLKMVLDCAHGATYHIAPMLFRELGAEVVVIGAAPDGLNINAGVGSTHIDNLAAKVREYGAHLGIAFDGDGDRVLMADDQGNPVDGDDLLYVLARSWQASGRLTGTVVGTLMTNYGLEQALAALNIPFQRAKVGDRYVHQALVEGGGTLGGETSGHLLCLDRATTGDGIVSALQVLEALGRDGHSLRKALSSLSKVPQKTVNVRLDGGAAKAIVEAANVQQALQQAQAAVQGRGRAFLRPSGTEPVVRVTVEADDARLMQDTLDRLSGAVRDAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: PPNP_ECOLC
Sequence: MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: CAS2_KORCO
Sequence: MRGGNLKVLVVYDITDDSLRLKVAEILKDLGLFRIQKSAFIGEMTSQERENMEEILRRQNLGPSDRIDVFPICDRDLKMHSQIGRGKFGRGPP
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: TSGA_YERP3
Sequence: MNNSNRIRLTWISYLSYALTGALVIVTGIVMGNIAEYFNLPIASMSNTFTFLNAGILISIFLNAWLMEIIPLKRQLVFGFILMLIAIAGLMVGHNLMIFSISMFIFGVVSGITMSIGTFLVTHMYEGRQRGSRLLFTDSFFSMAGMIFPIAAAMLLARHIEWYWVYACIGLLYVGIFVLTLCSEFPVLGHKATDQSKPVVKEKWGVGVLFLAIAALCYILGQLGFIQWVPEYATKTFNMNISQAGQLVSNFWISYMIGMWIFSFILRFFDLQRIVTVLAAMATLAMYLFVSTDNPAYLSYYILALGFVSSAIYTTLITLGSLQTKVSSPKLVNFILTCGTVGTMLTFVVTGPIVANNGVHAALATANGLYLAVFILCLALGFFTKHRSHGHVTH
What are the official names of this protein?
Protein TsgA homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OR4DA_HUMAN
Sequence: MEMENCTRVKEFIFLGLTQNREVSLVLFLFLLLVYVTTLLGNLLIMVTVTCESRLHTPMYFLLHNLSIADICFSSITVPKVLVDLLSERKTISFNHCFTQMFLFHLIGGVDVFSLSVMALDRYVAISKPLHYATIMSRDHCIGLTVAAWLGGFVHSIVQISLLLPLPFCGPNVLDTFYCDVHRVLKLAHTDIFILELLMISNNGLLTTLWFFLLLVSYIVILSLPKSQAGEGRRKAISTCTSHITVVTLHFVPCIYVYARPFTALPMDKAISVTFTVISPLLNPLIYTLRNHEMKSAMRRLKRRLVPSDRK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4D10, Olfactory receptor OR11-251.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIS1_AJECH
Sequence: MARLLTNRQADELHKSIIAYLSANDLPNTAAALRAELNLTEEDFDATAVKKYETLLEKKWTSIVRLQKKIMDLEARNAALQSELDNLTPASLLKPRRDPTSWLPTHPPRYSLESHRDTINCIAFHPKFSSLASGSDDFTIKIWDWELGELEMTLKGHTRAVLDVDYGSPQGITMLASCSSDLSVKLWDPAEGYKNVRTLLGHDHSVSAVRFIPCRNLLASASRDKDVRIWDVTTGYCVRSIQGHTGWVRDVCPSFDGNFLFSSGDDMTARLWDISAIPNPENKVTMAGHEHFIECCALAPPTSYQYLAPVAGLKGPSYPKSAAEFMATGSRDKTIKVWDVRGTCLMTLIGHDNWVRGIVFHPAGKYLLSVSDDRTLRCWDLSQEGKCVKTIKDAHDRFVTCLSWAPGVAKDVPAIPSNTAKGESSEIKETLKSPDVQIRCVIATGSVDRKLQIFAA
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for nuclear migration during vegetative growth as well as development.  Required for retrograde early endosome (EE) transport from the hyphal tip.  Required for localization of dynein to the mitotic spindle poles.  Recruits additional proteins to the dynein complex at SPBs.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.
Protein: RL3_LACPL
Sequence: MTTKGILGKKVGMTQVFTESGELVPVTVVEVQPNVVLQVKTVENDGYEAIQLGVDDKREVLTNKPAQGHAAKAKTTPKRFIREIRNVELGDYTVGDEVKADIFAAGDAVDVTGITKGHGYQGNIHKDGQSRGPMAHGSRYHRRPGSMGAIINRVFKGKKLPGRMGNHQRTMQNLQIVRADVENNVLLIKGNVPGANKSFVTVKTSVKSK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DNLJ_BACMK
Sequence: MSKEIAKKRIEELRDLLNTFNYQYHVLDNPSVSDAEYDRDMQELIKLEAENPEFMSEDSPSIRVGGTVLDIFEKVTHKSPMLSLGNAFNEGDLRDFDRRVHQGIDDANVRYICELKIDGLAVSLHYEKGRFIQGATRGDGITGEDITQNLKTIKAIPLRLNEEVTLEARGEAYMPKRSFVKLNEEKEQNGEDVFANPRNAAAGSIRQLDPKIAAKRNLSMFVYGLANVEEKTIPSHSESLDFLGELGFKTNPNRRTCETIEDVIAYVEEWQEKRPHLDYEIDGIVIKVDDVAIQESLGTTAKSPRWAIAYKFPAEEVVTRLTGIELSVGRTGVVTPTAELEPVRVAGTIVRRASLHNEDLIREKDIRIGDYVVVKKAGDIIPEVVNVIFDKRTGEEEEYHMPTHCPACESELVRLEEEVALRCINPTCPAQIREGLIHFVSRNAMNIDGLGERVITQLFDADYIRTFADLYSLTKEQLLELERFGEKSATNLVQAIENSKENSLERLLFGLGIRHVGAKAARTFAEHFETMDELVKATEEELKTINEIGEKMAQSVVTYFDNEDVLELLQQFKEYGVNMAYKGIKIADLQNVESYFAGKTVVLTGKLEVMGRSEAKKKIEALGGKVTGSVSKSTDLLVAGEAAGSKLAQAEKHNVEVWNEERFLQELNK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: LNBB_BIFB1
Sequence: MEKSSNRRFGVRTVAAIVAGLMVGGMCTAMTASAADDSAAGYSATAPVNLTRPATVPSMDGWTDGTGAWTLGEGTRVVSSDALAARAQSLASELTKFTDVDIKAATGSATGKDISLTLDASKKAELGDEGFKLNIGSKGLEVIGATDIGVFYGTRSVSQMLRQGQLTLPAGTVATKPKYKERGATLCACQINISTDWIDRFLSDMADLRLNYVLLEMKLKPEEDNTKKAATWSYYTRDDVKKFVKKANNYGIDVIPEINSPGHMNVWLENYPEYQLADNSGRKDPNKLDISNPEAVKFYKTLIDEYDGVFTTKYWHMGADEYMIGTSFDNYSKLKTFAEKQYGAGATPNDAFTGFINDIDKYVKAKGKQLRIWNDGIVNTKNVSLNKDIVIEYWYGAGRKPQELVQDGYTLMNATQALYWSRSAQVYKVNAARLYNNNWNVGTFDGGRQIDKNYDKLTGAKVSIWPDSSYFQTENEVEKEIFDGMRFISQMTWSDSRPWATWNDMKADIDKIGYPLDIREYDYTPVDAGIYDIPQLKSISKGPWELITTPDGYYQMKDTVSGKCLALFTGSKHLDVVTQVGARPELRNCADVSVGQDQRNTANERNTQKWQIRADKDGKYTISPALTQQRLAIATGNEQNIDLETHRPAAGTVAQFPADLVSDNALFTLTGHMGMSATVDSKTVNPASPSKITVKVRAASNANTGDVTVTPVVPEGWEIKPGSVSLKSIPAGKAAIAYFNVVNTTGTGDATVQFKLTNTKTGEELGTTSVALTGSLTKDVEASDYAASSQETTGEHAPVGNAFDKNANTFWHSKYSNPSANLPHWLAFKASPGEGNKIAAITHLYRQDKLNGPAKNVAVYVVAASDANSVADVTNWGEPVATAEFPYTKELQTIALPNTIPSGDVYVKFQINDAWGLTETSAGVTWAAVAELAATAKATPVELTEPEQPKDNPEVTETPEATGVTVSGDGVANGALSLKKGTTAQLTAKVAPDDADQAVTWASSDDKVVTVDKTGKVTAVAKGVAKVTATTANGKSASVTVTVTEDSEVPGPTGPTEPTKPGTEKPTTKPTTKPNDGKLSATGADTAVLATIAALFALAGGAVVAVRRRSVR
What is the function of this protein?
Present in the infant gut, this enzyme is involved in the assimilation of type-1 human milk oligosaccharides (HMOs).  It hydrolyzes via a retaining mechanism the beta-D-GlcNAc-(1->3)-beta-D-Gal linkage in lacto-N-tetraose (LNT or beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc), an abundant HMO unique to human breast milk, releasing lacto-N-biose (LNB or beta-D-Gal-(1->3)-D-GlcNAc) and lactose (PubMed:18469123, PubMed:23479733).  Is a key enzymatic factor for growth and proliferation of B. bifidum in the gut ecosystem of breast-fed infants (Probable).  Has substrate preference for unmodified beta-linked LNB since it does not hydrolyze the fucosylated forms of lacto-N-tetraose (lacto-N-fucopentaose I and II) or lacto-N-neotetraose.  Is also able to display transglycosylation activity in vitro (PubMed:18469123).
What are the official names of this protein?
Lacto-N-biosidase, LNBase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
Protein: TRPV1_RAT
Sequence: MEQRASLDSEESESPPQENSCLDPPDRDPNCKPPPVKPHIFTTRSRTRLFGKGDSEEASPLDCPYEEGGLASCPIITVSSVLTIQRPGDGPASVRPSSQDSVSAGEKPPRLYDRRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRPVEGLPPYKLKNTVGDYFRVTGEILSVSGGVYFFFRGIQYFLQRRPSLKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLIEDGKNNSLPMESTPHKCRGSACKPGNSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKAFRSGKLLQVGFTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRSGRVSGRNWKNFALVPLLRDASTRDRHATQQEEVQLKHYTGSLKPEDAEVFKDSMVPGEK
What is the function of this protein?
Does not display channel activity in response to noxious chemical compounds, such as capsaicin and the vanilloid resiniferatoxin.  Channel activity is not elicited by mildly acidic extracellular pH, and only slight channel activity is observed in response to noxiuos heat stimuli.
What are the official names of this protein?
Transient receptor potential cation channel subfamily V member 1, TrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid receptor type 1-like.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendritic spine membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Mostly, but not exclusively expressed in postsynaptic dendritic spines.