PharMolix/UniProtQA huggingface dataset:
Protein: VATL_ASCSU
Sequence: MSYDLATAERAAYAPFFGYMGAASAQIFTVLGAAYGTAKSAVGISSMGVMRPELIMKSVIPVIMAGIIGIYGLVVAMVLRGKVTSASAGYTLDKGFAHLAAGLTCGLCGLGAGYAIGIVGDAGVRGTAQQPRLFVGMILILIFSEVLGLYGMIVALILGTS
What is the function of this protein?
Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
What are the official names of this protein?
V-type proton ATPase 16 kDa proteolipid subunit c, V-ATPase 16 kDa proteolipid subunit c, Vacuolar proton pump 16 kDa proteolipid subunit c.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YBJQ_ECO45
Sequence: MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PYREL_PICTO
Sequence: MKSLEELYNRAIEMKNKGMSDKEISTELHLSVNTVTWLLSKEFVNERSAKDVKIGWRSAGVFGSRIGSLAEIMIDIAEEESNKMNLNIDAFLGITINGIPFATLASYMTGKELIVYRPHPSRKEGFFSSNFASVVNKNVVIMDDVVSTGETMKRTIEDVKKSGGKPVLCIVIASKLNIDEINGVKIRAIMRTVMV
What are the official names of this protein?
PyrE-like protein.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: RL29_VESOH
Sequence: MDVKELRNQSVSALNEMLIKLLKEHFEFRMQHKSSQLDNFSKLGKTKKSIAQIKTIIRQKQA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: UGPB_SALTY
Sequence: MISLRHTALGLALSLAFTGQALAVTTIPFWHSMEGELGKEVDSLAQRFNQANPDYKIVPVYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIKPVYEVFKDAGINFDESQFVPTVAGYYTDAKSGHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQELADYTAKLRAAGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDGTDAVLEFNKPEQVKHIALLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLANIRQYAKFNYGVGMMPYDADIKGAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKPENAAEWHQKTGYLPITTAAYELTREQGYYDKNPGADIATRQMLNKPPLPFTKGLRLGNMPQIRTIVDEELESVWTGKKTPQQALDTAVDRGNQLLRRFEKASKS
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Binds G3P.
What are the official names of this protein?
sn-glycerol-3-phosphate-binding periplasmic protein UgpB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ACYP_SHIFL
Sequence: MSKICIIAWIYGRVQGVGFRYTTQYEAKRLGLTGYAKNLDDGSVEVVACGEEGQVEKLMQWLKSGGPRSARVERVLSEPHHPSGELTDFRIR
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: Y1280_ACTP7
Sequence: MPSFDIVSEITMHEVRNAVENANRVLSTRYDFRGVEAVIELNEKNESIKLTTESDFQLEQLIEILIGSCVKRGIEHNSLDIPSDAEHHGKLYSKEIKLKQGIETEMAKKITKLIKDSKIKVQTQIQGEQVRVTGKSRDDLQAAIQLVKGAELGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein APP7_1280.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: FABH_SALAR
Sequence: MYTKIIGTGSYLPEQVRTNADLEKMVETSDEWIVTRTGIRERHIAAPNETVATMGFTAANRALEMAGIDKDQIGLIVVATTSATHAFPSAACQIQSMLGIKGCPAFDVAAACAGFTYALSIADQYVKSGAVKHALVVGSDVLARTCDPSDRGTIIIFGDGAGAVVLSASEEPGIISTHLHADGRYGELLTLPNADRVNPDNPIYLTMAGNEVFKVAVTELAHIVDETLAANNLDRSELDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTSAASVPCALDEAVRDGRIKAGQLVLLEAFGGGFTWGSALIRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAK_STAAM
Sequence: MLKRSLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASYFEPTGPYLMVNVTGVDGKGNELLSPHYVEFPIKPGTTLTKEKIEYYVEWALDATAYKEFRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVVIEKK
What is the function of this protein?
Potent plasminogen activator that converts plasminogen into plasmin.  It forms a 1:1 complex with plasmin, which in turn activates other plasminogen molecules (By similarity).
What are the official names of this protein?
Staphylokinase.
What is the protein family that this protein belongs to?
Belongs to the staphylokinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOA_SHIFL
Sequence: MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARSKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TTCA_YERE8
Sequence: MQEKQVVNQKEQYDLNKLQKRLRRNVGQAIADFNMIEEGDRVMVCLSGGKDSYTMLDILQNLQKSAPINFTLIAVNLDQKQPGFPEDILPAYLDKQGVEYKIVEENTYGIVKEIIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKLKGMPPKLMSDDGKHVVIRPLAYCREKDIERFAIAREYPIIPCNLCGSQPNLQRQVIKDMLRDWDKQYPGRIETMFSAMQNVVPSHLNDHKLFDFKNITHNSEIVDGGDLAFDREELPLQPVSWQPEDAEDGDTQPLVRLDVLEIK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBRA_ECOHS
Sequence: MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHISARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNEITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSAEILRAVLLKQPEKSNAAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKDYPTRFTSPTSRM
What are the official names of this protein?
Protein CbrA.
What is the protein family that this protein belongs to?
Belongs to the CbrA family.
Protein: LIMU_LIMPO
Sequence: LEEGEITSKVKFPPSSSPSFPRLVMVGTLPDLQEITLCYWFKVNQLKGTLGHSRVLBMFSYATAKKDNELLTFLDEQGDFLFNV
What is the function of this protein?
Lectin that binds sialic acid (PubMed:409430).  Displays antiviral activity and therefore may contribute to defense against infections (PubMed:7481093).
What are the official names of this protein?
Limulin.
What is the protein family that this protein belongs to?
Belongs to the pentraxin family.
Protein: PSAC_THAPS
Sequence: MSHTVKIYDTCIGCTQCVRACPTDVLEMVPWDGCKSGQIASSPRVEDCVGCKRCETACPTDFLSVRVYLGAETTRSLGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RL3_YERPS
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEIEANRVTQVKSLENDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLPEGQEFTAGQEISVEIFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGHMGDERVTVQSLDVVRVDAERNLLLVKGAVPGATGGNLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: BKRF4_EBVG
Sequence: MAMFLKSRGVRSCRDRRLLSDEEEETSQSSSYTLGSQASQSIQEEDVSDTDESDYSDEDEEIDLEEEYPSDEDPSEGSDSDPSWHPSDSDESDYSESDEDEATPGSQASRSSRVSPSTQQSSGLTPTPSFSRPRTRAPPRPPAPAPVRGRASAPPRPPAPVPQSTKDKVPNRPTRPVLRGPAPRRPPPPSSPNTYNKHMMETTPPIKGNNNYNWPWL
What is the function of this protein?
Histone-binding protein that binds to histones H2A/H2B, H3/H4 and cellular chromatin to overcome the host DNA damage response triggered by the viral genome ends.  Interferes with histone ubiquitination and recruitment of repair proteins.
What are the official names of this protein?
Tegument protein BKRF4.
What is the protein family that this protein belongs to?
Belongs to the lymphocryptovirus BKRF4 family.
What are the subcellular locations of this protein?
Virion tegument.
Protein: LOLB_ECOSE
Sequence: MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQDVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEITYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: DAPD_SHIBS
Sequence: MQQLQNIIETAFERRAEITPTNADTVTREAVNQVIALLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGHVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_AERHH
Sequence: MSKITTTNLLKMKQEGQRITAITAYDATFAKLFDDEGAHVLLIGDSLGMVLQGGQDTLGVSMDEMVYHTRCVVRGTTNALVVTDMPFMSYATPEQTYQNAARLMAAGARMVKMEGGDWLCDSIRHLTRNGVPVCGHLGLTPQSVHVFGGFKVQGRDEFQAQEIYRQALELQAAGIQLLVLECVPTSLAERISKALRIPVIGIGAGPATDGQILVMHDAFGITSGYVPKFTKNFLAETGDMRAAIRLYVKQVSEGTFPGPEHCFN
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_WOLSU
Sequence: MQSKRSRVLVKFSGEALAGENGFGIDTKILGFIASEIRSLVENKIEVGIVIGGGNIIRGVSAAQDGVIRRTSADYMGMLATVINAVAMQEALEHAGLDVRVQSAIELKEICESYIYRRAIRHLEKGRVVIFGAGTGNPFFTTDTAATLRAIEIGANMIIKATKVDGVYDKDPNKFSDAKKLDTLSYEEALDDRIKVMDDTAIALAKDNRLPIVVCNMFKPGNLLKIIQGDNGLCSVVGQRQ
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_HELPG
Sequence: MAISKEEVLEYIGSLSVLELAELVKMFEEKFGVSATPTVVAGAAVAGGAAAESEEKTEFNVILADSGAEKIKVIKVVREITGLGLKEAKDATEKTPHVLKEGVNKEEAETIKKKLEEVGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ATPB_SALG2
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNEKLVLEVQQQLGGGIVRTIAMGSSDGLSRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIDEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: 60A_DROME
Sequence: MSGLRNTSEAVAVLASLGLGMVLLMFVATTPPAVEATQSGIYIDNGKDQTIMHRVLSEDDKLDVSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGCH
What is the function of this protein?
Required for the growth of imaginal tissues and for patterning of the adult wing.
What are the official names of this protein?
Protein 60A, Protein glass bottom boat.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
Protein: ATPF2_GLOC7
Sequence: MFDFDATLPLMALQFLVLAVVLNAVFYKPLGKALDSRADYIRSNENQAREQLAKAQNLAQEYEKQLGDARRQSNEIIAAAQAQAKQIADEKIAQAQKEAQAQKEAAAKEIEQQKQEAMTALEQQVDALSRQILEKILGSELVK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', ATP synthase F(0) sector subunit b', ATPase subunit II, F-type ATPase subunit b', F-ATPase subunit b'.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RPOA_MESM1
Sequence: MEKFIKINWTENKTKRINDFSTSFIVQPLEKGLATTLGTAIRRVLLSSISSVAPFAVKIKGVEHEFMAINKVTEDVPQILLRLRDIKIAYNPEIFEDGKIYKLSLKSNKEAGDIYAKDFILPIGAEIVNPGLLIATTAAANVLEIDVFVRAGRGYVDFEENKKYIDEIKTNLTSSISNGQYIAVDSNFSPIEKVSFSSSELNTSSVIVQEKLEMEIVTKGTIDAKNAIAQAAKILVAHLNIIGDVNSLNIKDIFEEGNTEKEHSKTQNILIQSLDLSIRSFNALKRANYTTVQQLEALSLDDLKNIKNLGEKSINEIVEKLEKYNVFLDKGEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL15_PSEF5
Sequence: MKLNDLSPAPGSRREKHRPGRGIGSGLGKTGGRGHKGQTSRSGGTIAPGFEGGQQPLHRRLPKFGFVSLKAMDRAEVRLSELAKVEGDIVTVQSLKDANVINQNVQRVKIMLSGEVTRAVTIKGIAATKGARAAIEAAGGKFEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: Y3937_AERHH
Sequence: MTGIKRPMSQYQDDNEWEDWGPSKSQLKRDAEALQKMGEEIVSLSHSELEKIPLDEELAEAVELGRKLKPKKDESFRRHLQFIGRLMRSRDVEPIVEALSIIKNRHSTVNARLHRLEQWRERLINEGDSALNELMSQFHELDRQKLRQLIRTANKERELNKPPVAYREMYQYLRGEIEDLL
What are the official names of this protein?
UPF0307 protein AHA_3937.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: HSLU_BURO1
Sequence: MSTMTPAEIVSELDKHIIGQAKAKKAVAVALRNRWRRQQVAEPLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFIKIEATKFTEVGYVGRDVDSIVRDLIEISVKQTREAEMRKVRSKATDQAEDRILDILLPQPRAVGFGGNAEHANDDNNATRQTFRKRLREGQLDDKEVELDLEQPSVGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIKEALKLLTDEEAAKMLNEEEVKTKAVQNVEQNGIVFLDEIDKITSRNNEGSGGEVSRQGVQRDLLPLVEGTTVNTKYGMVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELDSLSVEDFEAILDATDASLVKQYQALLATEDVQLEFAADGIRRLAEIAFAVNEKTENIGARRLYTVIEKLLEEVSFSAGNHAGERVTIDAKYVDRALGEVAQDEDLSRYVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
Protein: CEIP2_MOUSE
Sequence: MYAAGSRGHSPAFLQPQNGNGHRSPGYVPGKVVPLRPAPPPKNHASAKLTSRSQDAPATFAFSPEEQRTPSESRKRKRHKNTFICFAITSFSFFVALAVILGISSKYAPDENCPDQNPRLRNWDPGQDSAKHIVIKEGDLFRLTSDATVDSIVIQDGGLLVFGDDKDGSKNITLRTRYILIQDGGALHIGAEKCRYRSKATITLYGKSDERESMPIFGKKFIGVEAGGTLELHGAQRTSWTMLARTLHSSGLPFGSYAFEKDFSRGLNVRVIDQDTARVLENEKFDTHEYHNESRRLQEFLRAQEPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIQGLGYRQAWALVGVIDGGSSSCNESVRNYENHSTGGKALAQGEFYTLDGQKFSVTAYSEWSQGISLSGFRVDIADGVKLHLLDDVSTWEAGDRIVVASTDYSMYQAEELTLLRCPECSRSQVKVKEIPQYLHVGEIIDGIDMRAEVGLLTRNIVIQGEMEDSCYAENHCQFFDYDTFGGHVMIEKNFTSVHLSYVELKHMGQQHMGRYPVHFHLCGDVDSKGGYSQPASVDGLSVHHSFSRCITVHGTSGLLIKDTIGFDTLGHCFFLEDGVEQRNILYHNLGLLTKPGTLLPTDRNSSMCTVMRDGVFGNYVPVPTTDCMAVSTFWIAHPNNHLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLEKPELTPLGIFYNNRVHSNFKAGLFVDKGVKTTNASASDPREYLCLDNSARFRPHQDADPEKPRVAAIIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGKGLTFASDGSFPSDEGSSQEVTESLFVGESRNYGFQGGQNKYMGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTKSTFKKYVPTPDRYSSAIGFLMKNSWQTTPRNNVSLVKFGPQVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDTYVGRMDNYLIRHPNCVNVTKWNAVICSGTYAQVYVQTWNTPNLSMIITRDEYPSHPMVLRGINQRAISPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKDDWIRVGLCYPANTSFQVTVGFLQRQNGSLSRIEDYEPARSMEELQKKPSERKFYFDSGTGLLFLYLRAHSHRDGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYKKPSAVKRMPAMLTGLCQGCGTHQMVFTSDPHKSYLPVRFQSPGKAEIQRGDPSIISVNGTDFTFRSAGALLLIVDACSVPFRVKEKRMFLSADVSHMEEYFKASIPPRSIVLLSTRGEIKQLNISDSLAVLGLAKPAHLYSKGSVVFLGFSGNFAPSWTKLFTSPDEQGLGVLEQFLPLQMEEYGCSRTGSVHRRDLDLLQQALKVL
What is the function of this protein?
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (By similarity).  Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity).  Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate (By similarity).
What are the official names of this protein?
Cell surface hyaluronidase, Cell migration-inducing hyaluronidase 2, Transmembrane protein 2.
What is the protein family that this protein belongs to?
Belongs to the CEMIP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: HLY3U_STAUR
Sequence: MSDFVNAISEAVKAGLSADWVTMGTSIADALAKGADFILGFFN
What is the function of this protein?
Virulence factor.  Causes hemolysis of erythrocytes.  Acts synergistically with beta-hemolysins from S. aureus ATCC 25923.  Cytotoxic towards human dermal fibroblasts.
What are the official names of this protein?
Hemolysin H3U.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal hemolytic protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: A85A_MYCMR
Sequence: PTGSGVVGLSMAGSSALILAAYHPDQFVYSGSLSALLDPSQGMGPSLIGLAMGDAGGYKASDMWGPKDDPAWARNDPMLQVGKLVANNTRIWVYCGNGKPSDLGGDNLPAKFLEGFVRTSNMKFQAAYNAAGGHNAVWN
What is the function of this protein?
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M. tuberculosis to murine alveolar macrophages (AMs).  They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor).  They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM.  FbpA mediates triacylglycerol (TAG) formation with long-chain acyl-CoA as the acyl donor and 1,2-dipalmitoyl-sn-glycerol (1,2-dipalmitin) as the acyl acceptor.  It has a preference for C26:0-CoA over C18:1-CoA (By similarity).
What are the official names of this protein?
Diacylglycerol acyltransferase/mycolyltransferase Ag85A, DGAT, Acyl-CoA:diacylglycerol acyltransferase, Antigen 85 complex A, 85A, Ag85A, Fibronectin-binding protein A, Fbps A.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial A85 antigen family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cytoplasm.
Protein: Y888_HELPJ
Sequence: MVLEVKNLSFKYSQKLILDKLSFSVPKNSITSILAPNGSGKTTLLKCLLGLLKPLEETEIKACNKDILPLKPYEKAKLIAYIPQVEYYAFNFSVLDFVLMGKATHLNLFAMPKAKHIKEATSVLERLDLESLKDQGINDLSGGQRQMVLLARSLLQRTPLLLLDEPTSALDLKNQALFFDAIKDEMKKRELSVLVNIHDPNLVARHSTHVVMLKDKKLFLQASTPIAMTSHNLSALYDTPLEAIWHDDKLVVYAL
What is the function of this protein?
Part of a binding-protein-dependent transport system for an iron chelatin.  Probably responsible for energy coupling to the transport system (Potential).
What are the official names of this protein?
Probable iron chelatin transport ATP-binding protein jhp_0821.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.