PharMolix/UniProtQA huggingface dataset:
Protein: HTF_PERFU
Sequence: QVNFSPNW
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, PerFu-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPRE2_PONAB
Sequence: MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTVSSPTSCEHRRIYTLGHLHDSYPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSEDVDSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKEDGERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA
What is the function of this protein?
Negatively regulates Ras signaling pathways and downstream activation of MAP kinases.  Recruits and translocates NF1 to the cell membrane, thereby enabling NF1-dependent hydrolysis of active GTP-bound Ras to inactive GDP-bound Ras (By similarity).  Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity).  Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity).
What are the official names of this protein?
Sprouty-related, EVH1 domain-containing protein 2, Spred-2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Detected in the cytoplasm of the stratum spinosum cells, where it is associated with cytoplasmic vesicles that are supposed to be secretory granules.
Protein: DNAA_STRM5
Sequence: MDAWSRSLERLEAEFPPEDVHTWLKPLQADLRVDSLVLYAPNAFIVDQVRELYLARIRELLAHFAGFSDVFLEIGSRPRPVEAQNAPFSTPSAHVSSEPQVPFAGNLDNHYTFANFVEGRSNQLGLAAAFQAAQKPGDRAHNPLLLYGGTGLGKTHLMFAAGNAMRQANPGAKVLYLRSEQFFSAMIRALQEKTMDQFKRQFQQVDALLIDDIQFFAGKDRTQEEFFHTFNALFDGKQQIILTCDRYPREVEGLEARLKSRLAWGLSVAIEPPDFETRAAIVLAKARERGAEIPDDVAFLIAKKMRSNVRDLEGALNTLTARANFTGRAITTEFAQETLRDLLRAQQQAISIPNIQKTVADYYGLQIKDLLSKRRTRSLARPRQVAMALTKELTEHSLPEIGDAFAGRDHTTVLHACRQIRTLMEADGKLREDWDKLIRKLSE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP15_CAEEL
Sequence: MSTKNRDRLVVTEDSDDDNEREEMSSGGESGEEGPSSVDGGAGDADETVAFPAIERRKKKVIKKLTKKEQSLKKSVKEYRIKLALVKPDITTDREKERNLRRVATKGVVQLFNAVSDRQKTMSDAVKEKMTARERREARQRFDGKNFDSDRFADSGYVGAKKEVKGEDDDGEDQMDIGEEQIDTGNYSDED
What are the official names of this protein?
RRP15-like protein.
What is the protein family that this protein belongs to?
Belongs to the RRP15 family.
Protein: STRD1_CAEEL
Sequence: MADTTILDTTCSSTLAANVEFSHATDSAIGISLKNATITEAEGVPNLKETGYDCVRYMGTCNGGQIYLGRERKKLKDYVAIKKFAIDDVDDYAAIAKESSNLRLMHHPNIIELCECFVYERSIYQITPAMNLGSLFDIVFEYMKWGINEKSAAAITRQLLDALSYLHQRRYIHRDLKPKHILIDSSGNVKLSGFRFMIELNHHLDCVFEFDAHLQNQLYYLAPEVLAQNIHGYTSKSDIYMLGISICEAINGVMPFGELEPLEMLHRKLNGQVPRPVDMISLKDDQKMGLDISHRPQEHLTRRFSKEMHEFIANCLDYDPQQRGSASDLKSSAWLGSKIHKNLGPVDVRQELNLDYAHFDLSLWEQEPLIPMEPDQKYEIVFDYSPIS
What is the function of this protein?
Pseudokinase which may act as an adapter for kinases sad-1 and par-4 and thereby is involved in several developmental processes.  Regulates cell-autonomously both neuronal polarity and synaptic organization when bound to sad-1.  Required for sad-1 localization to synapses (PubMed:20023164).  Required to establish germline stem cell (GSC) quiescence during dauer development, to promote cell shedding during embryogenesis and to control asymmetric cell division of the Q. p neuroblast lineage, probably when bound to par-4 (PubMed:20110331, PubMed:22801495, PubMed:23267054).  May be involved in maintaining the integrity of the early embryonic cortex when bound to par-4 (PubMed:20110331).
What are the official names of this protein?
STE20-related kinase adapter protein strd-1, STRAD STE20-related adapter homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Perikaryon. Nucleus. Cell projection, dendrite. Cell projection, axon. Synapse. Cytoplasm, cell cortex. Cytoplasm. Note=Localizes in punctate structures along the neurites of GABAergic motoneurons. Co-localizes with sad-1 at synapses (PubMed:20023164). Co-localizes with par-4 at the cell cortex of the early embryo. Cell cortex localization is regulated by par-4 (PubMed:20110331).
Protein: G3P_SPECI
Sequence: MVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGKSISIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKAAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMVHMASKE
What is the function of this protein?
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively.  Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity).  Modulates the organization and assembly of the cytoskeleton.  Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity).  Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.  Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.  Also plays a role in innate immunity by promoting TNF-induced NF-kappa-B activation and type I interferon production, via interaction with TRAF2 and TRAF3, respectively (By similarity).  Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis.  Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Nucleus. Note=Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal. Colocalizes with CHP1 to small punctate structures along the microtubules tracks.
Protein: GLMS_LEPIN
Sequence: MCGIVGYAGKKNAESVLVVGLICLEYRGYDSAGIAVLDQGDILVRKSKGKIKDLEAYLREFPAPGNVGIGHTRWATHGEPNQINAHPHTDTNSTVAVVHNGIIENYLELKSQLKKKGHVFQSLTDTEVLPHLLEESKKNGKSNKDSFLELFGKIHGKWAISSVFETEPDRVYFAQDGAPLLIGKGKGEYFLASDISPLTRNCEEVYYVNSGEWGYFSQNEFKLFDFSGKELNPTFKKQELRWEDLDKGGYPHYMIKEIHEQAGIFRKIIQERILENSEIVFPEIKLSKDVLSRVNRIIIQAAGTSYYAGMIGKHYLENFAKIQTDTEASSEFRYRNPVVEGDTLIMGISQSGETADTLASIHEAKAKFIKVVSLVNNVNSTIARESDSYIRTDAGPEIGVASTKAFTAQVLNLLLFSIYMANLKWLISDEEQKILIEEIKLLPAKIDRILAQASKIEEMSSHFTTAKDFIFLGRTYNHPVAMEGALKLKEISYIHASGYAGGEFKHGPIALITNEVPVVCIAPKSEIYTKMVSNIQEIKARKGIIISIVTEGDQEAKSLSDYCFEIPECSEILSPILNVIPLQLLAYYSAIARGCPPDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNS11_HUMAN
Sequence: METFPLLLLSLGLVLAEASESTMKIIKEEFTDEEMQYDMAKSGQEKQTIEILMNPILLVKNTSLSMSKDDMSSTLLTFRSLHYNDPKGNSSGNDKECCNDMTVWRKVSEANGSCKWSNNFIRSSTEVMRRVHRAPSCKFVQNPGISCCESLELENTVCQFTTGKQFPRCQYHSVTSLEKILTVLTGHSLMSWLVCGSKL
What are the official names of this protein?
Probable ribonuclease 11, RNase 11.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCS21_MYCSK
Sequence: MLSVPASSRIDFAGSPRPTVGVEWEFALVDAHTRDLSNEAATVIAEIGETPHVHKELLRNTVEVVTGICENTGEAMADLHDTLKVVRRIVRDRGMELFCAGTHPFANWSTQQLTDAPRYAELIKRTQWWGRQMLIWGVHVHVGISSAHKVMPIISSLLNQYPHLLALSASSPYWDGSDTGYASNRAMMFQQLPTAGLPFQFQSWPEFERFVHDQKKTGIIDHMNEIRWDIRPSPHLGTVEIRVFDGVSNIAELGSLVALTHCLVVDLDRRLDAGEQLPVMPPWHVQENKWRAARYGLDAEIILDADSNERLVTEDLDDLLTRLQPVARSLDCADELAGVAEIYRHGASYQRQRRVAEEHDGDLLAVVDALVAELEL
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-1, Gamma-glutamylcysteine synthetase 2-1, GCS 2-1, Gamma-GCS 2-1.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: NU1C_THEVB
Sequence: MESGIDLQGQFISALQSLGLSHDLAKLLWLPLPMLMMLIVATVGVLVAVWLERKISAAVQQRIGPEYIGPLGILAPLADGLKLIFKEDVLPANSDRWLFTLGPAVVVIPVFLSYIIVPFGQNLLISNLAMGVFLWIALSSIAPIGLLMAGYASNNKYSLLGGLRAAAQSISYEIPLALAVLAVAMMSNGLGTVEIVEQQSQYGILSWNVWRQPIGFLVFWIAALAECERLPFDLPEAEEELVAGYQTEYAGMKFALFYLGAYVNLVLSALLVSVLYFGGWSFPIPLETIANLLGVSETNPFLQIAFAVLGITMTLIKAYFFVFLAILLRWTVPRVRIDQLLDLGWKFLLPVGLVNLLLTAGLKLAFPVAFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PHS_CAEEL
Sequence: MHSSYSHFLQRLRTSVSYLSVSHFPSTSSHRLFSTTIGVFARKKMPLLTESERTEQLSGLKTAGWKLVEGRDAIQKEFHFKDFNEAFGFMTRVGLKAEKMDHHPEWFNVYNKVDITLSTHDCGGLSPNDVKLATFIESIVKK
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: CO1A2_CROSI
Sequence: RNGLPGPIGPAG
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-2(I) chain homolog, Peptide 4.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
Protein: YAS2_SCHPO
Sequence: MPEGAGRPWNLTELEEEKLKTMWSYLFKLFGITLLERTESWYTVKTHLSDDSSSSSSHRLSSVSYAKSRTRLELTSSSHGSDTRSFNDKTKNVHLERVEKIASEWDPEGLRVCFWDAVNCDDPDGLLLRFLRARKWNVEAALEMFMKTVHWRSREMNVGEIVCNADHLDKDDDFVRQLRIGKCFIFGEDKHNRPVCYIRARLHKVGDVSPESVERLTVWVMETARLILKPPIETATVVFDMTDFSMSNMDYGPLKFMIKCFEAHYPECLGECIVHKAPWLFQGVWSIIKSWLDPVVVSKVKFTRNYRDLQQYINPDNILKEFGGPNPWRYTYPEPCQNEAEALKNVEARKSLRAKKDAIAKQYEEVTMDWILNNGDMAEVKQKRRKLASQLIDAYWNLDKYIRARSVYDRMGLIAPQTSHTLLLSQPTNGDVKESMVEVTSSAT
What are the official names of this protein?
CRAL-TRIO domain-containing protein C3H8.02.
Protein: PNCB_ECOLI
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: UBD_HUMAN
Sequence: MAPNASCLCVHVRSEEWDLMTFDANPYDSVKKIKEHVRSKTKVPVQDQVLLLGSKILKPRRSLSSYGIDKEKTIHLTLKVVKPSDEELPLFLVESGDEAKRHLLQVRRSSSVAQVKAMIETKTGIIPETQIVTCNGKRLEDGKMMADYGIRKGNLLFLACYCIGG
What is the function of this protein?
Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1-dependent manner.  Probably functions as a survival factor.  Conjugation ability activated by UBA6.  Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2).  Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha.  Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs).  May be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses.  Mediates mitotic non-disjunction and chromosome instability, in long-term in vitro culture and cancers, by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle.  May be involved in the formation of aggresomes when proteasome is saturated or impaired.  Mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN).
What are the official names of this protein?
Ubiquitin D, Diubiquitin, Ubiquitin-like protein FAT10.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Accumulates in aggresomes under proteasome inhibition conditions.
Protein: RS15_THEAB
Sequence: MNKEEIIKEFQIHEGDTGSTEVQIALLTARIKHLTEHLKKHPKDYHSRRGLMKLVGRRRKILKYLRNKDPESYKNVIQKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FUCO_HUMAN
Sequence: MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
What is the function of this protein?
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
What are the official names of this protein?
Tissue alpha-L-fucosidase, Alpha-L-fucosidase I, Alpha-L-fucoside fucohydrolase 1, Alpha-L-fucosidase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 29 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: KCY_BRUC2
Sequence: MKSFVVAPFIVAIDGPAASGKGTLARRIATHYGMPHLDTGLTYRAVAKALLDKGLSLDDEALATDAALSLDLLAMDKAVLSAHAIGEAASKVAVMPAVRRALVEAQRHFANALPSSVLDGRDIGTVVCPDAAIKLFVTASPEVRARRRFDEVLARGDTADFAEILADLKKRDERDMNRTDSPLRPAEDAHLLDTSEMSIEAAFLAAKKLIDHALAQHRG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1421_STAAM
Sequence: MKNYSFYQFVMTVRGRHDDKGRLAEEIFDDLAFPKHDDDFNILSDYIETHGDFTLPMSVFDDLYEEYTEWLKF
What are the official names of this protein?
UPF0346 protein SAV1421.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: PFDA_THEVO
Sequence: MARDVEAQLNYIESLISSVDAQIDAINKMVLEVQTTIQILSSDELRQSKERLISVGSGIFANGNLDLDSDLIVPIGSGVYIAEKRSETIERLKANIENLKESIQKLMDQRRTLVDQYNTVYTTEATRNIK
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCC1_BACSU
Sequence: MIKKLLIANRGEIAVRIIRACRELGIETVAVYSEADKDALHVQMADEAFCIGPKASKDSYLNVTNIVSVAKLTGTDAIHPGYGFLAENADFAELCEEVNVTFVGPSADAISKMGTKDVARETMKQAGVPIVPGSQGIIENVEEAVSLANEIGYPVIIKATAGGGGKGIRVARTEEELINGIKITQQEAATAFGNPGVYIEKYIEDFRHVEIQVLADNYGNTIHLGERDCSIQRRLQKLLEESPSPALDSEIREQMGDAAVKAAKAVGYTGAGTVEFIYDYNEQRYYFMEMNTRIQVEHPVTEMVTGTDLIKEQIKVASGMELSLKQEDVEFEGWAIECRINAENPSKNFMPSPGEIKMYLPPGGLGVRVDSAAYPGYSIPPYYDSMIAKVITYGKTRDEAIARMKRALSEFVIEGIETTIPFHLKLLEHETFVSGEFNTKFLETYDVMGS
What is the function of this protein?
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
What are the official names of this protein?
Biotin carboxylase 1, Acetyl-coenzyme A carboxylase biotin carboxylase subunit A 1.
Protein: SPRR3_HUMAN
Sequence: MSSYQQKQTFTPPPQLQQQQVKQPSQPPPQEIFVPTTKEPCHSKVPQPGNTKIPEPGCTKVPEPGCTKVPEPGCTKVPEPGCTKVPEPGCTKVPEPGCTKVPEPGYTKVPEPGSIKVPDQGFIKFPEPGAIKVPEQGYTKVPVPGYTKLPEPCPSTVTPGPAQQKTKQK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.
What are the official names of this protein?
Small proline-rich protein 3, 22 kDa pancornulin, Cornifin beta, Esophagin.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y307_PECCP
Sequence: MNQRAAGAVYEQQARRYLERAGLTFTAANVTLRGGELDLIMRDRHIWVFVEVRYRRNAHFGDAAASVTRHKQQRLLHAAAVWLAQRGASFDTVDCRFDVLAITGDRFDWIPNAFATQG
What are the official names of this protein?
UPF0102 protein PC1_0307.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: ATPB_HELP2
Sequence: MKAMEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAIAMDMTEGLVRNQVVKARGKMIEVPVGEEVLGRIFNVVGESIDNLEPLKPSLTWPIHRKAPSFEQQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVGKTVIIMELIHNVAYKHNGYSVFAGVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLDVLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSVQAVYVPADDLTDPAPASVFAHLDATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKHYEVATGIQQVLQKYKDLQDIIAILGLDELSEEDKKTVERARKIEKFLSQPFFVAEVFTGSPGKYVTLQETLEGFGGILEGKYDHIPENAFYMVGSIQEVLEKAKNMKNS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ACP_STAAT
Sequence: MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_BACHK
Sequence: MAQVQYYGTGRRKSSVARVRLVPGEGRVIINGRDFENYIPFAALREVVKQPLVATETLGNYDVLVNVNGGGYTGQAGAIRHGISRALLKADPEYRLTLKRAGLLTRDARMKERKKYGLKGARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: PAND_FRATT
Sequence: MLISVLKSKISYATVTGKDLFYVGSITIDSEIMKQANIIENEKVQVVNLNNGERLETYVIKGEPNSKTIALNGPAARRCEIGDQLFIISYTQVDPTRENIKPKLVDLKTGD
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_BORPE
Sequence: MALINRLDSRDPGFKTALSQLLAFEAEQDESIDQAAAGILADVRRRGDAALLEYTQRFDRLAVDDATALEIPQADWHAALDSLPAAQRQALEAAAARVRAYHERQRGETWTYTEADGTMLGQQITALDRVGLYVPGGKAAYPSSVLMNAIPAKVAGVPELIMVTPTPDGVRNPIVLAAAAIAGVDRAFAIGGAQAVGALAYGTATVPAVDKIVGPGNAYVAAAKRRVFGTVGIDMIAGPSEILVICDGKTPADWIAMDLFSQAEHDELAQSILLCPDAAFLAEVEAAIERLLPGMPRADILRVSLANRGALILVRDLEEACAIANDIAPEHLEISTEQPQRWTALIRHAGAIFMGRYSSEALGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSLIQVSREGAQTLGRIAAELALGEGLQAHAASAQYRLDQP
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: LCFA_SALTY
Sequence: MKKVWLNRYPADVPAEINPDRYQSLVELFEHAATRYADQPAFVNMGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVVNVNPLYTPRELEHQLNDSGAAAIIIVSNFAHTLEKVVEKTSVQHVILTRMGDQLSTAKGTVVNFVVKYIKRLVPKYHLPDAISFRSALQHGYRMQYVKPEVVAEDLAFLQYTGGTTGVAKGAMLTHRNMLANLEQVKATYGPLLHPGKELVVTALPLYHIFALTMNCLLFIELGGQNLLITNPRDIPGLVKELAKYPFTAMTGVNTLFNALLNNKEFQQLDFSSLHLSAGGGMPVQNVVAERWVKLTGQYLLEGYGLTECAPLVSVNPHDIDYHSGSIGLPVPSTEAKLVDDDDNEVAPGEAGELCVKGPQVMLGYWQRPDATDEIIKDGWLHTGDIAVMDEDGFLRIVDRKKDMILVSGFNVYPNEIEDVVMQHSGVQEVAAVGVPSGSSGEAVKLFVVKKDPALTDDALITFCRRHLTGYKVPKQVEFREELPKSNVGKILRRELRDEARGKVDNKA
What is the function of this protein?
Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids.
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase, Long-chain acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Partially membrane-associated.