PharMolix/UniProtQA huggingface dataset:
Protein: CHL1_DEBHA
Sequence: MGNLEANDVGNNSRKYNHPFEPYDIQIQLMDAIYDAIDNYKIGLFESPTGTGKTLSLICSSMTWLREYKKNSTFRETEDSESEDEPEWVKQAYQKTIANRTKVRAQEYERLLDDLSENYDVSKVSVLPEKKVKRQKPEQEQDENFIPADYYSDSELDSKYENDKLTSEINELLSRVDGPKETVEPVNDCPVKIFFSSRTHSQLSQFSHQLNMTEFESSLDNIPERIKFSPLASRKQLCIHPKISKLSNVSSINDACIDLQQSSKNSCEYIPKLHNTQSEEIVKKFSDLSFTKIHDIEDLGKLGNKLKICPYYSVRKGIDVTEIIALPYQMLLQDSTRSALNLNIDDSIIIIDEAHNLLDVISSIYSVSITSNELSDITKSLKFYLNKFIKRLNSGNRINIMKLIKLCQVLEKFISSNSKDGKIKHGDEIITSDIFEGTTGDLVNIHKIEQFLNKSKIAYKIESYMQKLNDSESIKNRSNPLLFKITKFLKCLTNPSKEGKFFWDKTNDSVSINYMLLDPSEIFRDIVKRARCVLLCGGTMEPMNDYTNYLFPYIPPEQIKKFSCGHIIPQENLEVFPIGNYNDISFEFSFDKRNNSKMIIELGHAILNIIESTPDGIVIFFPSYKYLNVVMNVWRQNKIIESLTKVKAIFQEPEDSSKVEKVLNDYSSTNKSEKHSALLLSVVGGKMSEGINFSDELARGVIMIGLPFPNIFSAELIAKRKFIEESTIAKGGTKSQAMVNAKNFYENICMRAVNQSIGRSIRHKNDYSIIYLFDQRYGSDKIQDKLSGWVKQKLFTRGRCTDFNQVIKETQDFFRQKLLG
What is the function of this protein?
ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity).  May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity).  Has a specific role in chromosome segregation during meiosis II (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase CHL1, Chromosome loss protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZC3C1_XENLA
Sequence: MATTCEEVLVSPVKSTAVTPLKIRELINEGIVCGERSGIGRKEASETPEENTAFEDLPGNNSYESTSKDAFFSRVESFSSLKWAGKPPELCPLICAKYGWCNIECDMLKCSSCNAYLCASLQPILDFSKYKQRCVELQEALRKAHEKFCFWPDSPCPEHFWALLVTEPSSVLSDFVERFHNLCHLEMQLPSLKHEDVKSMDITEDTVSRLLRLIEDELKPKEGREANSHSLPSDSLQVHISACILALCGWNTSFSSGSLCIINCPRCMRKVGLWAFQQLETVELDNSLSAPGTPVSPAEGHERSPLGFMSPSRRVTRSRDAEQSPAFAYGRTRSSDLLSPADSEAVRNRPVTRSMGQGENTGLGNELHSSPHRRAKRPRLCSSSSSDTSPRSCFDPLSQHRSWCPWVNVCQASGTNTMGSEIQEEARRKEYGWKEVLKVLLAEENSRTISNPDTSSVPEKSHKVFRIFRQWQLAASS
What is the function of this protein?
Probable component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1).
What are the official names of this protein?
Zinc finger C3HC-type protein 1-like, NIPA-like protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL30_BREVE
Sequence: AEKKTVTVKQTGSPIXXXK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: CTU1_XENTR
Sequence: MPVNCSSCEERRAVLRRPKTGHSLCKDCFFHAFEEEIHHTIVSAKLFNPGEKVGIGASGGKDSTVLAHVLKVLNERYAYGLDLILVSVDEGISGYRDDSLETVKRNQQQYELPLKIVSYQELYGWTMDQIVKQVGLKNNCTFCGVFRRQALDRGAMMLGVNKICTGHNADDIAETVLMNFLRGDIARLRRCTSITTGSEGAIPRCKPLKYAYEKEIVLYAYFKKLDYFSTECIYSPNAYRGHARAFLKDLEAIRPSSIMDIIHSGENLSVKEDVRMPVQGTCTRCGYISSQSLCKACVLLEGLNRGLPKLGIGKHHKLHHKLLSQEPLSEQEERKLKAVDF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, ATP-binding domain-containing protein 3, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_PALPL
Sequence: MTATLERRESASLWERFCTWITSTENRLYIGWFGVVMIPTLLTATSVFIIAFVAAPPVDIDGIREPVAGSLLYGNNIISGAIIPSSAAIGIHFYPIWEAASLDEWLYNGGPYQLIVLHFLLGVCCYIGREWELSYRLGMRPWISVAFTAPVAAAAAVFLVYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHQLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRALHFFLGAWPVVGIWLTSMSVSTMALNLNGFNFNQSVVDSQGRVINTWADILNRANLGMEVMHERNAHNFPLDLASGDSCPVALVAPSING
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS12_SHEHH
Sequence: MATVNQLVRKPRAPKVDKTNVPALAACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCAGVSERRQGRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: GPSB_BACMK
Sequence: MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEAFHKEFDQLKQQNARLKRELEEQKVAATQVPQQPVQTPVAQPVYNNTNTDILKRLSNLEKAVFGSKLYE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: DEGP4_ARATH
Sequence: MLFRFLQTLARFCRFLLISVLGFRFSPLLLLGYVKLQDENKHNSESALASGTDAKQPEAAENVTSSSIDFAVNSVVKVFTVYSMPSVLQPWRNWPQQESGGSGFVISGKKILTNAHVVADHIFLQVRKHGSPTKYKAQVRAIGHECDLAILEIDNEEFWEDMIPLELGEIPSLDESVAVFGYPTGGDSVSITKGYVSRVEYTRYAHGGTTLLAIQTDAAINPGNSGGPAIIGNKMAGVAFQKDPSADNIGYIIPTPVIKHFLTAVEENGQYGGFCTLDISYQLMENSQLRNHFKMGPEMTGILINEINPLSDAYKRLRKDDIILAIDDVLIGNDAKVTFRNKERINFNHFVSMKKLDETVLLQVLRDGKEHEFHIMVKPVPPLVPGHQYDKLPSYYIFAGFVFVPLTQPYIDSTLICNCAIKYMPEKAGEQLVLADDINAGYTDFKNLKVIKVNGVQVENLKHLTELVETCWTEDLRLDLENEKVVVLNYANAKEATSLILELHRIPSANEYDYQWQS
What is the function of this protein?
Putative serine protease.
What are the official names of this protein?
Protease Do-like 4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: NRDI_STAEQ
Sequence: MKVVYYSFSGNVRRFISRAGIKDTFEITQDNCNESVNEPYILVTGTIGFGEVPQPVQSFLNVNHTQLQAVAASGNRNWGQNFAKAGHTISEEYKVPLMMKFEVQGTNKDIIEFKDKVGNFNENHGRKEIQSY
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: CMLO5_RAT
Sequence: MALYQIRQYQERDHKHVVDLFSSGIKEHIPAAFRYTLLLPKTLLFLFAAPLTIVLASGSWLLAVVCIFFLLLLLRFLAGQPFKEYVAMCLQTDMADITKSYLNSHGSFWVAESGGQVVGIVAALPVKESPSGRKQLQLFHLSVSSQCRGQGIAKALVRTVLQFARDQGYTDVVLETSIIQQGAMTLYEAMGFQRTGKNLENSIIKWLIGFFFISFHVCFPFCSGT
What is the function of this protein?
May play a role in regulation of gastrulation.
What are the official names of this protein?
Probable N-acetyltransferase CML5, Camello-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the camello family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PEPF_ASPNG
Sequence: MLFRSLLSTAVLAVSLCTDNASAAKHGRFGQKARDAMNIAKRSANAVKHSLKIPVEDYQFLNNKTKPYRVESLPDVHFDLGEMYSGLVPIEKGNVSRSLFFVFQPTIGEPVDEITIWLNGGPGCSSLEAFLQENGRFVWQPGTYQPVENPYSWVNLTNVLWVDQPVGTGFSLGVPTATSEEEIAEDFVKFFKNWQQIFGIKNFKIYVTGESYAGRYVPYISAAFLDQNDTEHFNLKGALAYDPCIGQFDYVQEEAPVVPFVQKNNALFNFNASFLAELESIHEQCGYKDFIDQYLVFPASGVQPPKAMNWSDPTCDVYDIVNNAVLDPNPCFNPYEINEMCPILWDVLGFPTEVDYLPAGASIYFDRADVKRAMHAPNITWSECSVESVFVGGDGGPEQEGDYSANPIEHVLPQVIEGTNRVLIGNGDYDMVILTNGTLLSIQNMTWNGKLGFDTAPSTPINIDIPDLMYNEVFIENGYDPQGGQGVMGIQHYERGLMWAETFQSGHMQPQFQPRVSYRHLEWLLGRRDTL
What is the function of this protein?
Removes any amino acid from the C-terminus of a long peptide.  Digests preferentially peptides containing a positively charged residue in P1' position, as well as arginine, lysine or phenylalanine in P1 position of ester substrate.  Catalyzes also peptide synthesis.
What are the official names of this protein?
Serine-type carboxypeptidase F, Proteinase F, CPD-II.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
Protein: SYY_LISMF
Sequence: MNIIDELEWRGAIYQQTDEEGLRKWVEEKQISLYCGIDPSGDSMHIGHLIPFMILRRFQNAGHRPIILVGGATGTIGDPSGKKEERKLQSMEQISKNVESLRVQLGKIFDFEGNSAASMVNNYDWTKDVSILDFLRDYGKEFNVNTMLSKDIVASRLEVGISFTEFAYQILQAMDFNHLYEFNDCRLQIGGSDQWGNITAGLDLIRKKQGENAKAFGLTIPLLTKADGTKFGKSEGGAIWLNPEKTTPYEFYQFWINTDDRDVVKYLKYFTFLTEAEIDELAKQVETEPHLRAAQKTLAAEMTKFVHSEEALEQALKISKALFSGDVKALTADEIEQGFKDVPTFVAEDTEANLVDWLVTLGIEPSKRQAREDVANGAIYINGERQQDLEKIMDASDRIENKFTIVRRGKKKYFLVSYK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24E_METM5
Sequence: MEWKTCSFCEGTIEPGCGKKYVKKDGSVMHFCSSKCEKNFKLGRVGRKLKWTNTFKRINRGQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: MKK2_ASPFU
Sequence: MSSSPVPLLRPPVPGNRGNGPRPPKLTLGIPPSPNSRPVDGNGVGPAAAAPEAPQPQRPSTRPAPPQLRLATPMGSSSDVPQEVPRLANGRPAPPPLATTGLNESTGHSRSSSFTYLDGKASGPASASSSNYSALSFAMGLRQPHGSTPDPSSAISSVYSDREGGVQMERDNSVNGLLPDLDKLSLEKGRPLDVDDLDDEGWLAASEQKKIIELGSLGEGAGGAVTRCKLKDGKTVFALKIITTDPNPDVKKQIVRELNFNKDCASEHICRYYGAFMDKSTGTISIAMEFCEGGSLDSIYKEVKKLGGRTGEKVLGKIAEGVLNGLTYLHSRKIIHRDIKPSNILLCRNGQVKLCDFGVSGEFGTKGDANTFIGTSYYMAPERITGQSYTITSDVWSLGVTLLEVAQHRFPFPADGTEMQPRAGLIDLLTYIVRQPIPKLKDEPENRIRWSDNFKYFIECCLEKEPPRRATPWRMLEHPWMLDMKNKKVNMANFVRQVWGWQD
What is the function of this protein?
Mitogen-activated protein kinase kinase; part of the cell wall integrity (CWI) signaling pathway composed of pkcA, the bck1-mkk2-mpka MAPK cascade and the downstream rlmA transcription regulator (PubMed:19715768).  The CWI signaling pathway regulates cell wall integrity and pyomelanin formation (PubMed:19715768).  CWI controls also oxidative stress response, gliotoxin production, iron adaptation and asexual development (PubMed:21883519, PubMed:32005734).  Finally, CWI is constitutively required for A. fumigatus to cope with the temperature increase found in the mammalian lung environment, during infection (PubMed:33010083).  Mkk2 directly activates mpkA during vegetative growth and under cell wall stress conditions (PubMed:19715768).
What are the official names of this protein?
Mitogen-activated protein kinase kinae mkk2, MAPKK mkk2, MEK mkk2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: BPT_METS4
Sequence: MTSHPRDAPQFYLTAPSPCPYLPGQHERKVFTHLVGRRARDLNEILTQGGFRRSQTIAYRPACETCRACVSVRVVVGDFEPSASQRRVLKRNRDLVGQPQPNRPASEQYALFRRYLDARHGDGGMVDMTVLDYAMMVEDSHVETHLVVYRKRGPDTAINGRGVGAPIAVCLTDVLSDGLSMVYSFYEPSEADRSLGTFMILDHIERARLLGLPYLYLGYWVEGSRKMDYKAKFGPQERLMPQGWARVG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_BACFN
Sequence: MTVKEKIEQLRLQLHQHNYNYYVLNAPEISDKEFDDLMRELQDLEQEHPEYKDENSPTMRVGSDINKNFTQVAHKYPMLSLSNTYSENEVTDFYDRVRKALNEDFEICCEMKYDGTSISLTYENGKLIRAVTRGDGEKGDDVTDNVKTIRSIPLVLHGDNYPEVFEIRGEILMPWEVFEALNREKEAREEPLFANPRNAASGTLKLQNSAIVASRKLDAYLYYLLGDNLPTDGHYENLQEAAKWGFKISPLMRKCQTLQEVFDFINYWDVERKNLNVATDGIVLKVNSLKQQRNLGFTAKSPRWAIAYKFQAERALTRLNMVTYQVGRTGAVTPVANLDPVQLSGTVVKRASLHNADIIEGLDLHIGDMVYVEKGGEIIPKITGVDTSVRFMIGEKVKFITHCPECGSKLIRYEGEAAHYCPNETACPPQIKGKIEHFISRKAMNIDGLGPETVDMFYRLGLIHDTADLYQLTTDDIRGLDRMGDKSAENIIKGIMQSKEVPFERVIFALGIRFVGETVAKKIAKSFKDIEELENADLETLINIDEIGEKIARSILNYFANESNRKLVDRLKTAGLQLYRPEEDLSGHTDKLAGQSIVISGVFTHHSRDEYKDLIEKHGGKNVGSISSKTSFILAGDNMGPAKLEKASKLGIKIMNEEEFLKLIS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GACE_DICDI
Sequence: MDHRKSVDFTNEYIKQQTENQNHTPRGHRMMANFTIRKWNSETNFNEDDYGAIPTKSSIANLLNKFLKSRPTKDDLEMNKILKSEYKPITLRYSLIEILCNHIEKYALEQEGIFRVSGSNQQIRLFWQTFTTDNIEFPINEHNVAGALKLYIREQSEPLVPYEMFSNFISQLGDGGPVTFTAITNLMSKITPENLKIIKRLIRTAVIIVRHSQLNKMDANNMGIVFGPNIFKSRPDSPNIFSEAKYSNESVSFLISNYLNVFPDLEIPILGTETNTEENELLNNNNNNNNVIMPTTTTTTTSASSSILPTDSSNNNGGGSASSPVTKSIPLSSIGSSSTSPIISPSSSSSSSPIVGTNLTTGSIHSTSPTPFSLLATTTSTTTTNSNKVNSIINSTSQSKSQLLPIHPSLLDTNQMIERVEGNPLSQMKRKDFSITHHLSTKLQKTKHFRKEEIWDCFLILKVSGNLVNVKNSTTTTTTSTSTSTSTSTSTSTSSTTTNQPNSITQSNSASNNSLINNGKIKKSTTNLISQSNSQSSLQLNQTNSNNNNIVTLTPVYILITSQNVFFFDTRIYNIQYILPHSRLKEISVDVVNKGLFSILDGESHKLSFFLVPRPRVIDLLVRSLERGRAIAKLTNKSLASLQSRKFPLLESNSGAGGTSNFGKLPESRPVFESLAQNGFTELDVWEGTVDLLEVVKKFHHILIPSADQSKCVVEFLLPAIPEFKGIYRKSYKLDSKTTVYKIICLICEKAKLEPSKFLLRTLKGRTLFDNKSLGDFGLGTLFTSWQLRLIALESPESTGNFVVEFLMPDIPEFKGMQKKAIKVDAYQPLKRIMKGLCDKLKIPNHHYYHLIGPEGEVLGDNDVLSSIGLGIKYKTCKMKLAKKVFPVGKNPELDTPMVRSLVIDNIIGLAWSKIKDRHNERIRLYCKQMLDYIVDQTFVEIAKAELVPKRVAMLGKNSRYEFYHALSLKEEEDMILMDIQGYKETVYQSRSIVPSEPDSSPNYPLYRQKLPTIRGVGPINSIRDIKVNSAKNNFLSELKDNNKQQQQQQIGNTNDEHTIKPSQRIKYIAPTPVLNNPNSIVQLLALKPGASKLVEQLKNRMTITTSKINIFDVEDLVPKNSPVLSRKSYKL
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacE, GTPase activating factor for raC protein E.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_RHOPS
Sequence: MKVRNSLKSLRSRHRDNRLVRRKGRIYVINKVQRRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: HUTH_BACC2
Sequence: MITLTGHTLTIEEMKRLLLEGEGVTACPTSMQKVAECREVVEKIVEDGKVVYGITTGFGKFSDVLIQKDDVKALQHNLIQSHACGIGDPFPEEVSRGMLILRANTMLKGVSGVRPLVVNMLLEFVNRKIHPVVPQQGSLGASGDLAPLSHLALVLLGEGEVFYKGKRVHAMVALTEEGLEPIELEAKEGLALINGTQAMTAQGVLSYIEAEATAYQAELIASMTIEGLQGIIDAFDENVHKARGYKEQVDVASRIRDILHDSKLTTKQGELRVQDAYSLRCIPQVHGASWQVLNYVKEKLEIEMNAATDNPLIFDGGEKVISGGNFHGQPIAFAMDFLKVGMAELANISERRIERLVNPQLNDLPPFLSPEPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIASRHAHQIIQNARRVLSIEMICAMQAAEYRGIENMSTVTKSFYHQGRQQVPSITNDRIFSTDIENIAHWLKTNYSIKERLDVNAAL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NA1B_BUNCN
Sequence: GVACRCDSDGPTVRGDSLSGTLWLTGGCPSGWHNCRGSGPFIGYCCKK
What is the function of this protein?
Binds to the sodium channels Nav1. 1/SCN1A (EC(50)=165 nM), Nav1. 5/SCN5A (EC(50)=103 nM) and Nav1. 6/SCN8A (EC(50)=133 nM), thereby delaying their inactivation (PubMed:18342901, PubMed:21802465).  Also inhibits Nav1. 2/SCN2A, Nav1. 3/SCN3A, and Nav1. 4/SCN4A, but to a lesser extent (PubMed:21802465).  Inhibits Nav1. 5 differently from isoforms Nav1. 1 and Nav1. 6.  In Nav1. 5 the effect consists in a right-shift of inactivation; whereas in both Nav1. 1 and Nav1. 6 the effect consists in an incomplete inactivation (PubMed:21802465).
What are the official names of this protein?
Delta-actitoxin-Bcg1b, Delta-AITX-Bcg1b, Cangitoxin II, Cangitoxin-2, Cangitoxin-II, CGTX-II.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: PXPA_BURMS
Sequence: MEIDLNADLGEGCGSDEALLDLVTSANIACGWHAGGAQAMRDCVRWAVEKGVSIGAHPSFHDPENFGRKEMDLPASEIYAGVLYQLGALSAIAQAEGGRIAHVKPHGALYNQAAREPEIADAVVSAIHDFDPSLAVFGLAKSGFVDAAQQAGLVAVEEVFADRGYRADGSLVPRSQPGALVDDENEMLARTLEMVRGQRVRAVTGEWVPLNAQTVCLHGDGPHALAFAKRIRDALEAAGIDVHAPGALHAGERA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: RL17_PARD8
Sequence: MRHNKKFNHLGRTNTHRDAMLSNMACSLIKHKRIFTTTAKAKALRKYVEPLITKSKEDTTHSRRVVFSNLQDKFAVTELFKEIAQKIGDRPGGYTRIIKTGNRLGDNAAMCFIELVDYNENMLKDTAAKKAPKTRRSRKKATASVAEAPTAEAASEEKAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: NADA_APLKU
Sequence: MSPVAIVACVCLAVTLTRISPSEAIFPTPELQNVFLGRCKDYEITRYLTILPRVKSDCRALWTNFFKAFSFKAPCNLDLGSYKDFFQRAQQTLPKNKVMFWSGVYDEAHDFADDGRKYITLEDTLPGYMLNSLVWCGQRDKPGFNQKVCPDFKDCPVQARESFWGTASSSYAHSAEGDVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTKVKVIVLHQLGQKIIERCGAGSLLDLEMVVKAKKFGFDCVENPKSVLFLLCADNPNARECQLAKRYYRIA
What is the function of this protein?
Synthesizes cyclic ADP-ribose (cADPR), a second messenger for calcium mobilization from endoplasmic reticulum (PubMed:7961800).  Might make the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate (By similarity).  Does not have cADPR hydrolase activity (PubMed:7961800).
What are the official names of this protein?
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase, ADPRC, ADRC, NAD glycohydrolase, NAD(+) nucleosidase, NADase.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosyl cyclase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Note=Localized to vesicles or granules within ova of all stages.
Protein: VATF_NEOFI
Sequence: MAASAVSYKERQFLAVIGDEDSVTGLLLAGIGHVTDGPDAQRNFLVVDSKTETSAIEKAFQNFTQERKDIAVLLINQHIAERIRHSVDSFADPFPAVLEIPSKDHPYDPEKDSVLKRVRRLFGE
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit F, V-ATPase subunit F, V-ATPase 14 kDa subunit, Vacuolar proton pump subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DJC14_RAT
Sequence: MAQKHPGERGLCGVHHSGGSSLITSGSSVDPEILSFSGLRDSKETAPNGTRCLKEHSDPKCTQPPNPAHWSDPSHGPPRGPGPPREGGYPDESETCSEESGVDQELSRENETGYQEDGSPSFLPIPSACNCQGSPGVPEGTCSEEGDGSSSSFCHHCTSPALGEDEELEEEYDDEEPLKFPSDFSRVSSGKKPPSRRQRHRFLTKEDVRDSGRRDPKAPGRHRLARKRSQTDKRRGLGLWGVEELCQLGQAGFWWLIELLVLVGEYVETCGYLIYACRKLKGSDLDLFRIWVGVWARRLGGWARVMFQFLSQSFFSVAGLFIRLLRVVGAFLLLALALFLGCLQLGWRFLVGLGDRLGWRGKAAWLFSWLDSPALHHFLTLLKDSRPWQQLVRVIQWGWLELPWVKQRTQRQGTAHVASGRYCQPEEEVARLLTMAGVPEDELNPFHVLGVEATASDIELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNPERRKEYEMKRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFGSRVPGTSGRQRATPESPPADLQDFLSRIFQVPPGPMSNGNFFAAPHPGPGTTSTSRPNSSVPKGEAKPKRRKKVRRPFQR
What is the function of this protein?
Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface.
What are the official names of this protein?
DnaJ homolog subfamily C member 14, Dopamine receptor-interacting protein of 78 kDa, DRiP78.
Protein: CH10_PSE14
Sequence: MKLRPLHDRVVIRRSEEETKTAGGIVLPGSAAEKPNRGEIVAVGTGRVLDNGEVRALAVKVGDKVVFGPYSGSNTVKVDGEDLLVMSENEILAVVEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_AGARV
Sequence: MLMPKRVKHRKQFRGSMAGKATRGNKITNGEYGIVALEPCWIKANQIEAARVAMTRYIKRGGKVWIKIFPEKPVTHKPMGVRMGKGKGALEYWVAVVKPGRVLFEISGVPEDVAKEALRLATHKLPCKCKVVSRADLEGGESNEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: Y3137_ACIAD
Sequence: MPSFDIVSELELFEVNHAVQNTQKEIQTRFDFRGQDVSIELNEKSKEIKISTESDFQCEQVYSMLENHFYKRKIDVQALDPQKATASGKNVVQVIKLKDGLDSDTAKKINKAIKESGIKVQSSIQGDKIRVTDKKRDTLQQVMTFLREQQFGLPLQFNNFKD
What are the official names of this protein?
UPF0234 protein ACIAD3137.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.