PharMolix/UniProtQA huggingface dataset:
Protein: NDKA_DROYA
Sequence: NKERTFIMVKPDGVQRGLVGKIIERFEQKGFKLVALKFTWASKELLEKHYADLSARPFFPGLVNYMNSGPVVPMVWEGLNVVKTGRQMLGATNPADSLPGTIRGDFCIQVGRNIIHGSDAVESAEKEIALWFNEKELVTWTPAAKDWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Abnormal wing disks protein.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: CECB_BOMMO
Sequence: MNFAKILSFVFALVLALSMTSAAPEPRWKIFKKIEKMGRNIRDGIVKAGPAIEVLGSAKAIGK
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-B, Lepidopteran-A/B.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y268_MYCGE
Sequence: MQLKKPHFQPNKIANCIVIGGMIALGKTTIANTLANHIQAAKVVCELETNDQLVELLLAKMYERSDELLYSPLFQLYFTLNRFGKYQNNCNTINPTIFDRSIFEDWLFAKHNIIRPAVFSYYNQLWNRLAKELVNKHGVPNLYVILDGDWKLFEKRLFMRNRKVEIDNFTKNQLYFQNLHRVYTGFMEAVCNDFGINYCIIDAKLPIVTIIKMILEKLKLQKLDWKFI
What are the official names of this protein?
Uncharacterized protein MG268.
Protein: TRMD_SALG2
Sequence: MFIGIVSLFPEMFRAITDYGVTGRAVKKGLLNIQSWSPRDFAHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGVDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVARFIPGVLGHEASAIEDSFADGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKC_STAAM
Sequence: MHKIFSKNNLIFFVFVAFIFVVIVLQFFVSSENATKVNLSQTFEPISWLHLLGTDDYGRDLFTRIIIGARSTLFVTVLTLIAIVVIGVTLGLFAGYKKGWIERLVLRFIDVGLSIPEFIIMIALASFFQPSLWNLVISITVIKWMNYTRLTRSIVNSEMNKPYIKMAQLFHVPTRTILIRHLTPKIIPAIIVLMVVDFGKIILYISSLSFIGLGAQPPTPEWGAMLQQGRDFISSHPIMLIAPASVIAITILIFNLTGDALRDRLLKQRGEYDESH
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Nickel import system permease protein NikC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AES_XENLA
Sequence: MMFPQSSSRHSGSSHMPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLAGEKSEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLHGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQLQVHQLSQLQALALPLTSLPMGLQAPSLPISASSGLLSLSALGSQGHLPKEDKNGHEGDRRPDDDGDKSD
What is the function of this protein?
May act as a transcriptional corepressor.  Has a possible role in the negative regulation of proteins containing WD-40 repeats.  May be required for the initiation and maintenance of the differentiated state (By similarity).
What are the official names of this protein?
Amino-terminal enhancer of split, Amino enhancer of split, Protein GRG.
What is the protein family that this protein belongs to?
Belongs to the WD repeat Groucho/TLE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPF_POLAQ
Sequence: MNLNATLFAQMIVFFVLWWVVARFVWPPLVKALDERSSKIADGLAAAERGKEALALASNEAEQELTKARQEGVQRVAEAEKRAQMSADEIRANAQAEAARIITQAKQDADQQVTSAREVLRAEVAVLAVKGAEQILRREVDAKAHGQLLDQLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PCGF6_RAT
Sequence: MEEAETDATENKRASEAKRASAMLPPPPPPISPPALIPAPAAGEEGPASLAQAGAPGCSRSRPPELEPERSLGRLRGRFEDYDEELEEDEEMEEEEEEEEEMSHFSLRLESGRADSEDEEERLINLVELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVVNLEEREKKQMHDFYKERGLEVPKPAVPQPVPASKGRTKKALESVFRIPPELDVSLLLEFIGANEDTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLERYQTLREIRRAIGDTAMQDGLLVLHYGLVVSPLKIT
What is the function of this protein?
Transcriptional repressor.  May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase.  Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.  Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.
What are the official names of this protein?
Polycomb group RING finger protein 6, RING finger protein 134.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPK3_AUSGA
Sequence: DPPFSPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-3, PK-3, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAS4_AERPE
Sequence: MRPVSMLKEYAYCPRVAYYMEVLRPSYRPTEPMNLSREIYSVDHVRGILRSSGFRIVKEEWAVPLRSKRLGLQGVADGVVVEGSLGIIVVEAKLSVRSNRWLHTRGRHVIFQAAAYALALEETRGYSVDYLAIVSLEDSKTYVVKMSPSLRRDVIRLADDMNKTLDDGLEPPPKPGRKCVACRFRRVCQPWVAERGSER
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  This may be a 5' to 3' ssDNA exonuclease (By similarity).
What are the official names of this protein?
CRISPR-associated exonuclease Cas4.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated exonuclease Cas4 family.
Protein: MUZZL_BPCA1
Sequence: MALKKEQHFFKGMQRDLSVSKFNPEYAFDAQNIRITAREHDTLLSVSNEKGNKEIPLQSPSGDPVVIDGVLLGQNVLNNYVTLFTKGTNDNIYRLENKGTYFETLILFSGNLNFSTDYPIESISVYENNNIQKVYWVDGLNQARVINITKDDYNNADDFDFVGTIHTSSKIEVSKVNGSGAFGQGVIQYAFTYYNKYGKETNIFRTSPLLYIAYSDRGASPEETVSCSFQINFTELDSSYDFIRVYSIHRTSIDATPTVRKVADLATDTKLYVDTGTTGEIVDPTLLLYVGGEEIAPYTMTQKDNTLFLGNYTLKRSLISTELKNQIKSDSIVTTILGGLDDAIESEWNVNTQYNSNYDLNYDSRIKGFQKGEIYRLGIQFQDNKGKWSEVVFIGDYECTERFKYTQYDTYGITLIPRFKVVISNSTTIQAIKNLGYINARGVVVFPTLEDRNILCQGILCPTVANYKDRLDNSPFVQSSWFSRPKQATETWKTEYSGTNHLSEFGEVPYFQHNEPIGSASLSEITRWEIQTSLGLVPYYNPSTTNAKDFVDGSPSEFLVDENIVTMHSPDVEFDDRLQNITNGKFKLRIIGTTHLTNTLSDISVITSTPTYGNYATGFYKGKVANMNISTSYYGGRQLSAGLFWSDNVKFQDPSPQDKLERLWMVYPWHRNGSLMNMGVPTEGTRAAALQRKIISNLKFASQNNYLPNQSVWEAEISGDANHTGITPVNSWTEGLVRIPAQANSNLGSLNYYANIDKVLTFNRSEQISEIYKNGYLIYTTKDWITDGKIADLFNNAISQTISVDQVQDWLTRIADTDKYGTEPVSMKYKSNPHLVFAFNYTESGKQLILPMKNNNNGYLAPSANSKPFWNPTAPEGAVYQDSINFTNENRAFFWLAELYRDSVVNRFGGDTEEAILNNTWLPSGDSVIIGDSINIEYTEGDTYYQRYDCLRTFAYTNEDQNSIVDIVSFMCESKVNIDGRYDKNRGQVNNLAVSPTNFNLFNPVYSQKNNFFTFRTIDYERFSINYFPNSITVTKEKSLGEDIDTWTNITLATTLDLDGDKGEIVSLNTYNNEIFCFQRRGLSNILFNSRVQIPTSDGMPIEITNGLKVSGKRYISNTIGCANKWSIAESPSGLYFIDNETNSLYLFNGEIVSLSDKLGFRQWISTHNVHVNWEPVGYNNYRSFYDKNNNDVYFTYKDHCLCYSELINQFTSFMSYEGVPAMFNVSSEFYAFKDGKMWEQFAGDYNMFFGEYKPFSITFVANAEEPNDKIFNTVEFRADSWDSDNLISNKTFDTLDVWNEYQHGTTPLTNLLGHPSPLKKKFRIWRANIPRAIANNRDRIRNTWAYIKLGMNTPNTYRTEFHDAIIHYFA
What is the function of this protein?
Forms the muzzle assembly at the distal part of the tail.  May serve as the gatekeeper to control the ejection of the cargo proteins.
What are the official names of this protein?
Muzzle protein, Gene product 44, gp44.
Protein: MSD8_AMAEX
Sequence: MSDINATRLPFVFVASPPCVGDDIAMVLTRGENLC
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:24050899).
What are the official names of this protein?
MSDIN-like toxin proprotein 8.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: ATG7_RAT
Sequence: MGDPGLSKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSAPTPARCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVGLDQRLSPKQIQALEHAYDDLCRTEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKLTVGVYDPCNLTQHPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNASGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEELIDSHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEQEGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV
What is the function of this protein?
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy.  Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine.  Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.  Required for autophagic death induced by caspase-8 inhibition.  Facilitates LC3-I lipidation with phosphatidylethanolamine to form LC3-II which is found on autophagosomal membranes (By similarity).  Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress.  Also plays a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation (By similarity).  Plays a role in regulating the liver clock and glucose metabolism by mediating the autophagic degradation of CRY1 (clock repressor) in a time-dependent manner (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, Autophagy-related protein 7, APG7-like.
What is the protein family that this protein belongs to?
Belongs to the ATG7 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure. Note=Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.
Protein: RPOB_RICM5
Sequence: MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNKGLQSILNSIFPISDSSNIANLEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDIDEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVVVSQMHRSPGVFFYHDEGKVHSSGKLLYSARVIPYRGSWLDLEFDAKDVIYFRIDRKRKLYITTLLRAIGMSTEEIIKFYYNSVTYKLVKNKGWAVKFIPQHITAHRLTSDLVDADTGNILLKAGQKITPRLAKKYFGEGLNNILVAHETLIGKYLSEDLRDPTSDEVLAKIGEMITADMLNVINALKIKNVNVLVINPQSGPYIRNTLFADKNQDREAALCDIFRVLRPGEPANIEAAESLFYNLFFDVERYDLSEVGRIKMNSRLELNISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQFRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFNTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRAGFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRRVKDGCVTDEVVYLSAIEEGKYKIGQANSKVNKDGKLQGEFINCRVEGGNFVMVEPYEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGTGVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKVDGSPSVDIYNLLKFQKSNHNTCINQKPLVKVGHYVKKNDIIADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDVFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALRHLDEVGIIYIGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQRAIAIEKQQIEKLAKDRDDELEIIEHFVFSWLEKLLVGQVIINGPKQVKVGQTITTEMLKGLSKGQFWQITVEDANVMNEIEQIKTHYDEKKEALDKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVISRIVPEEDMPFLEDGTVVDIVLNPLGLPSRMNIGQILETHLGWASINLAKKISTLVKEYKNKHIGIEQIKKFLIELYGENINSILERPEEEIISFCKKVSKGVHFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPYSLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFRSLCLNVKLEVTSS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ATPG_LACJO
Sequence: MAESLLELKKKIASIQKTGQITEAMRMVSGVKLNRTEKLDQEYTIYNDKVRATVSHLMSSQIVNQLGKETNEYSEFSGQSNIDYSSFFDLGTLASLVQPRKEIKSTGYLVISGDRGLVGSYNSQVIKNMMSIFKDADAQNKDVKILAVGSVAAQFFKKQNLNVVYEYSGVSDVPTYNEVRDIVQTAVKMYLNGVYDELFVCYTHHVNTLTSAFRVESMLPISDIDINHKETMPKDYIIEPDIDSVLKTVLPQFAKSMIFGAILDAKTAEHASSMTAMQSASQNADDVVSGLKTKLNRARQAQITTEITEIIGGANALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: WHIA_LISMO
Sequence: MSFASETKKELTHMDVSDSDAKVELAAFIRMNGAISFSSQLVIMDVQTENAAIARRMYQLLKDLYEVPIELLVRRKMKLKKNNVYIVRLKSGTRGILEDLRILEPPMTFTKSIDRGFVKKRSAKRAYLRGAFLASGSVNNPETSSYHLEIFSVYEEHNEAICALMNQFDLNARTLERKNGFITYLKEAEKITEFLSIIGATSALLHFEDVRIMRDMRNSVNRLVNCETANLNKTINAAVRQIDNIKYIQSTVGLEALPERLREIAALRIANEDVTLKELGEMLTTGQVSKSGINHRLRKLDQIAERLRSGETPAQVGLKISNS
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: SYN_XANCP
Sequence: MTVVSVEHALAGKIPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVATDTLPNFDEIKRLTSGCSLIAKGVLVKSQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMSPEFLREVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWISTPIITTSDAEGAGQMFRVSSLDMVNLPRTAQGEVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTRHLAEFWMIEPEIAFADLAEDARLAEQFLKYLFRAVLDERGDDLAFLAERVDKNAISKLEAFINAPFEQIDYTEAVKLLQNSGKKFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAQFGLDKEHYSWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_BRUAB
Sequence: MVTTLRQTDPDFEQKFAAFLSGKREVSEDVDRAVREIVDRVRREGDSALLDYSRRFDRIDLEKTGIAVTEAEIDAAFDAAPASTVEALKLARDRIEKHHARQLPKDDRYTDALGVELGSRWTAIEAVGLYVPGGTASYPSSVLMNAMPAKVAGVDRIVMVVPAPDGNLNPLVLVAARLAGVSEIYRVGGAQAIAALAYGTETIRPVAKIVGPGNAYVAAAKRIVFGTVGIDMIAGPSEVLIVADKDNNPDWIAADLLAQAEHDMAAQSILMTNDEAFAHAVEEAVERQLHTLARTETASASWRDFGAVILVKDFEDAIPLANRIAAEHLEIAVADAEAFVPRIRNAGSIFIGGYTPEVIGDYVGGCNHVLPTARSARFSSGLSVLDYMKRTSLLKLGSEQLRALGPAAIEIARAEGLDAHAQSVAIRLNL
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: UD17_RAT
Sequence: MAPADVPASLPLGLCLLLASGFGHAGKLLVVPMDGSHWFTMQMVVEKLLPKGHEVVVVVPEVSWQLGKPLNFTVKTYSVSHTQEDLNREFKFFIDSQWKTQQESGVLPLLTSPAQGFFELLFSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCGLTVAKYFSLPSVVFSRGIFCHYLEEGSQCPSPPSYVPRPILKLTDTMTFKERVWNLLSYMGEHAFCPSFFKTATDIASEVLQTPVTMTDLFSPVSVWLLRTDFTLELPRPVMPNVIHIGGINCHQRKPVSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH
What is the function of this protein?
UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile.  Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds.  Catalyzes the glucuronidation of endogenous estrogen hormone epiestradiol.  Also catalyzes the glucuronidation of the isoflavones genistein, daidzein, glycitein, formononetin, biochanin A and prunetin, which are phytoestrogens with anticancer and cardiovascular properties.  Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist caderastan, a drug which can inhibit the effect of angiotensin II.  Involved in the biotransformation of 7-ethyl-10-hydroxycamptothecin (SN-38), the pharmacologically active metabolite of the anticancer drug irinotecan.
What are the official names of this protein?
UDP-glucuronosyltransferase 1A7, UGT1A7, A2, UDP-glucuronosyltransferase 1-7, UDPGT 1-7, UGT1*7, UGT1-07, UGT1.7, UDP-glucuronosyltransferase 1A7C.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: C21AA_BACTU
Sequence: MTNPTILYPSYHNVLAHPIRLDSFFDPFVETFKDLKGAWEEFGKTGYMDPLKQHLQIAWDTSQNGTVDYLALTKASISLIGLIPGADAVVPFINMFVDFIFPKLFGRGSQQNAQAQFFELIIEKVKELVDEDFRNFTLNNLLNYLDGMQTALSHFQNDVQIAICQGEQPGLMLDQTPTACTPTTDHLISVRESFKDARTTIETALPHFKNPMLSTNDNTPDFNSDTVLLTLPMYTTGATLNLILHQGYIQFAERWKSVNYDESFINQTKVDLQRRIQDYSTTVSTTFEKFKPTLNPSNKESVNKYNRYVRSMTLQSLDIAATWPTLDNVNYPSNVDIQLDQTRLVFSDVAGPWEGNDNITSNIIDVLTPINTGIGFQESSDLRKFTYPRIELQSMQFHGQYVNSKSVEHCYSDGLKLNYKNKTITAGVSNIDESNQNNKHNYGPVINSPITDINVNSQNSQYLDLNSVMVNGGQKVTGCSPLSSNGNSNNAALPNQKINVIYSVQSNDKPEKHADTYRKWGYMSSHIPYDLVPENVIGDIDPDTKQPSLLLKGFPAEKGYGDSIAYVSEPLNGANAVKLTSYQVLQMEVTNQTTQKYRIRIRYATGGDTAASIWFHIIGPSGNDLTNEGHNFSSVSSRNKMFVQGNNGKYVLNILTDSIELPSGQQTILIQNTNSQDLFLDRIEFISLPSTSTPTSTNFVEPESLEKIINQVNQLFSSSSQTELAHTVSDYKIDQVVLKVNALSDDVFGVEKKALRKLVNQAKQLSKARNVLVGGNFEKGHEWALSREATMVANHELFKGDHLLLPPPTLYPSYAYQKIDESKLKSNTRYTVSGFIAQSEHLEVVVSRYGKEVHDMLDIPYEEALPISSDESPNCCKPAACQCSSCDGSQSDSHFFSYSIDVGSLQSDVNLGIEFGLRIAKPNGFAKISNLEIKEDRPLTEKEIKKVQRKEQKWKKAFNQEQAEVATTLQPTLDQINALYQNEDWNGSVHPASDYQHLSAVVVPTLPKQRHWFMEGREGEHVVLTQQFQQALDRAFQQIEEQNLIHNGNLANGLTDWTVTGDAQLTIFDEDPVLELAHWDASISQTIEIMDFEGRHRIQTACTWKRQRNSYRSTWRKRLETMTFNTTSFTTQEQTFYFEGDTVDVHVQSENNTFLIDSVELIEIIEE
What is the function of this protein?
Endotoxin with nematicidal activity.
What are the official names of this protein?
Pesticidal crystal protein Cry21Aa, 132 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryXXIA(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: DAPB_BACMK
Sequence: MKEIKVIIAGPRGRMGYEAVLLMERTAHFNLVAAIDYKHGGEKISDLPGMPALDAPIYADLHTCLDEVEADVLLDLTTPEIGKKHVTLAVERGLRSVIGTTGFTEEELKQLTENAKEKEVGTIIAPNFAIGAVLMMKFSQMAAKYFQDVEVIELHHDQKLDAPSGTAVKTVELIRQNRVPKEQGHPNETEQLEGARGANVDGIHIHSVRLPGLIAHQEVMFGGDGQMLTVRHDSFNRASFMSGVKLSIETVMNLDHLVYGLENIID
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMA2L_PONAB
Sequence: MAATLGPLGSWQQWRRCLLARDGSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQGKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQERVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDIDGKHEWRDCIEVPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDVFLPSVDNMKLPEVTAPLPPLSGLALFHIVFFSLVIFVFAIVIGIILYNKWQEQSRKRFY
What is the function of this protein?
May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins.  May function as a regulator of ERGIC-53 (By similarity).
What are the official names of this protein?
VIP36-like protein, Lectin mannose-binding 2-like, LMAN2-like protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Predominantly found in the endoplasmic reticulum. Partly found in the Golgi.
Protein: KA166_BUTOS
Sequence: MKILSVLLIALIICSINICSEAGLIDVRCYASRECWEPCRRVTGSAQAKCQNNQCRCY
What is the function of this protein?
Inhibits potassium channel.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 16.6, Toxin Tx608.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 16 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MDTK_ECO24
Sequence: MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSVIILQRASR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENGB_PELPB
Sequence: MKIVNTAFHISVSALSGLPEDSFPEIVFAGRSNVGKSTLLNSLTGVKGLAKTSATPGKTRLINYFLINRDVYFVDLPGYGYAAVGHAEKALWGNLLSSYIIQRRSISLVVLLLDSRHPAMQSDRAMISFLESHDRPYGIVLTKYDKLTQKEKVQTGRIMESCAAKAKFIVNYSSFSGKGKSELLAHFDQYICQ
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: STOP1_ORYSJ
Sequence: MDSGLGRSSETSLKALPSMASNATRNTDPDQQGVRFSSMDQPPCFARPGQSFPAFPPLFGVQSSSLYLPDDIEAKIGNQFESNPSPNNPTMDWDPQAMLSNLSFLEQKIKQVKDIVQSMSNRESQVAGGSSEAQAKQQLVTADLTCIIIQLISTAGSLLPSMKNPISSNPALRHLSNTLCAPMILGTNCNLRPSANDEATIPDISKTHDYEELMNSLNTTQAESDEMMNCQNPCGGEGSEPIPMEDHDVKESDDGGERENLPPGSYVVLQLEKEEILAPHTHFCLICGKGFKRDANLRMHMRGHGDEYKTAAALAKPSKDSSLESAPVTRYSCPYVGCKRNKEHKKFQPLKTILCVKNHYKRSHCDKSYTCSRCNTKKFSVIADLKTHEKHCGRDKWLCSCGTTFSRKDKLFGHVALFQGHTPALPMDDIKVTGASEQPQGSEAMNTMVGSAGYNFPGSSSDDIPNLDMKMADDPRYFSPLSFDPCFGGLDDFTRPGFDISENPFSFLPSGSCSFGQQNGDS
What is the function of this protein?
Probable transcription factor that may be involved in aluminum tolerance.
What are the official names of this protein?
Zinc finger protein STOP1 homolog, Protein STOP1 homolog.
What are the subcellular locations of this protein?
Nucleus.