PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_CLOBH
Sequence: MAKIIGIDLGTTNSCVSVMEGGEPVVIPNAEGSRTTPSVVSFQANGERLIGQVAKRQAITNPEKTIISIKRYMGTDHKVNIDSTEYTPQQISAMVLQKLKADAEAYLGEKVTQAVITVPAYFNDSQRQATKDAGKIAGLEVLRIINEPTAASLAYGLDKMDTNEKILVYDLGGGTFDVSILELGDGVFEVKATNGDTKLGGDDFDQKLIDYIAETFKAENGIDLRNDKMAIQRLKEAAEKAKIELSSATQTNINLPFITADATGPKHIDMNLTRAKFNELTHDLVQRTLEPIKKSLEGSGYAMSDIDKIIMVGGSTRIPAVQDAVKDFTGKELSKGVNPDEVVAMGAAIQAGVLTGEVKDVLLLDVTPLTLGIETFGGVSTTLIEKNTTIPTRKSQVFSTAADGQTSVEIHVVQGERSMAADNKTLGRFTLSGIAPAPRGIPQIEVTFDIDANGIVNVSAKDKGTGKEANITITASTNLTDDEIEKAVNEAKKFEAEDKKRKESIEIKNNADQIVYQTEKTLTDLGDKVSAEDKAQIEEKVKAVKDVKDGEDLEAIKKATEDLTQTFYGISSKIYQQANPEGAQGAGFDPNNMGGANAGNASAGNDKKDDNVVDADFKVEDDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CH60_PROA2
Sequence: MTAKDILFDAEARAKLKVGVDKLANAVKVTLGPAGRNVLIDKKFGAPTSTKDGVTVAKEVELEDAFENMGAQMVREVSSKTSDVAGDGTTTATVLAQAIYREGLKNVAAGARPIDLKRGIDLAVKDVVAELREISRDITGKKEIAQVGTISANNDPEIGELIAEAMDKVGKDGVITVEEAKGMDTELTVVEGMQFDRGYLSPYFVTNSEKMDADLEDPYILIYDKKISNMKELLPVLEKTAQSGRPLMIIAEDIEGEALATLVVNKLRGTLKVCAVKAPGFGDRRKAMLEDIAILTGGTVISEEKGYKLENATISYLGQAASITVDKDNTTIVDGKGQADDIKARIGEIKGQIEKSTSDYDTEKLQERLAKLSGGVAVLNIGASTEVEMKEKKARVEDALHATRAAVQEGIVAGGGVALIRAAKALDATNPENEDQKTGVDIIRRALEEPLRQIVANTGTTDGAVVVEKVKNSEGDYGFNARTEEYMNLIEAGVVDPTKVTRTALENAASVAGILLTTEAAITDIKEDGSDMPPMPGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGB3_PCV87
Sequence: MEAPAITHSSGCVCSDCQWSGSPTVDTKVYLGSGTHANTTKTRETSFLSVLNDNAWLFVIAALILCLYFIISKPHVDAVYTEFHQDLNGFSMKLAPGVPIDPKVIAAVKNWQKYPFGTDPRENMVTSIVSGLRHSFCILLLVVVLLVYVCHKP
What is the function of this protein?
Participates in the transport of viral genome to neighboring plant cells directly through plasmodesmata, without any budding.  TGBp2 and TGBp3 are necessary for intracellular delivery of TGBp1-containing vRNPs to plasmodesmata.  Can gate plasmodesmata and increase their size exclusion limit.  Induces host actin cytoskeleton network thickening, which probably plays a major role in virus cell-to-cell movement.
What are the official names of this protein?
Movement protein TGB3, P17, Triple gene block 3 protein, TGBp3.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae TGB3 movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host cytoplasm, host cytoskeleton. Note=Probably localizes to plasmodesmata-associated membrane compartments called peripheral membrane bodies (PMBs). Associates with host actin filaments.
Protein: Y3945_ROSS1
Sequence: MATIGRETTISWLGHGTFHILTPGGKKVLIDAWVDGNPSCPDEWKQRVRSEGLDVIFLTHGHFDHIADILALANETSATIVGQFDITSWIASKGVSQDRLVGFNKGGTVEVAGIRATMTHATHSSTFTDNGVIVPMGTEAGYVLRMENGFTIYHTGDTAVTMDMQIIGDLYHPELVILPIGDHFTMDPMQAAYALKLIRPTFAIPEHYGTFPILRGTPDQLREQCNAFGVNVTVIDLKPGESVS
What are the official names of this protein?
UPF0173 metal-dependent hydrolase RoseRS_3945.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: MURC_SINFN
Sequence: MKMPKTIGLVHFIGIGGIGMSGIAEVLHNLGHRVQGSDQSDSANVQRLREKGIKISVGHKAENLGDAEVVVVSTAIKKDNPELIAAREKFLPVVRRAEMLAELMRFRNAIAIGGTHGKTTTTSMVAALLDAGGLDPTVINGGIINAYGTNARMGAGEWMVVEADESDGTFLKLPADIAVVTNIDPEHLDHYGNFDAVRAAFRQFVENVPFYGFGVLCLDHPEVQSMVGKIEDRKVITYGENPQADVRYHNVRMDGATSVFDVEIRRRRTGQVIQLNGLRLPMPGRHNVSNATAAVAVAQRLGMEPEAIAKGLASFGGVKRRFTLTGEWNGASIFDDYGHHPVEIKAVLRAAREACQGRIVAVHQPHRYSRLSSLFEDFSACFNDADTILIAPVYAAGEDAIDGVNSQALVNSIKAAGHRDAQFLTGPEALAPVVSKIAQPGDFVVLLGAGSITYWAAALPKELAEISGS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_POPAL
Sequence: MKIEKSQRNLEIDRSRKNDFLYPLIFREYIYTFAHDRDLNRSILLENVSYDNKYSLLIVKRLITRMYQQNHLIISANDSNQNTFFRYNKNLYFQMISEGFAVIVEIPFSLRLVSSLERSEIVKSHNLRSIHSIFPFLEGKFPHLNYLSEGLIPYPIHLEKLVQILRYWVKDPSSLHLLRLFLHEYWNLNSLIIPKKSISFFVKKNQRFFLFLYNSHVYEYESVFFFLCKQSFHFRLTFYQVFLERIYFYGKIEHFVEVFTKDWGDSLCLLKDPFIHYIRYQGKSIFVSKDTPLLMKKWKYYLVNLCQCHFDVCFQPQKIHINPFSLYKHSFALLGYLSSSSVRLNLSVVRSQMLENAFLMDNIMNKLDTTVSIIPLIGSLAKMKFCNAVGHPISKPTWADFSDSDIIDRFVRICRNLSHYYSGSSRKKSLYRIKYILRLSCVKTLARKHKSTVRIFLKRLGSELLEEFFTEEEQIIFLIFPRASSISQKLYRGRVWYLDIICINELSNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: 3SA1C_NAJAT
Sequence: MKTLLLTLVVVTIVCLDLGYTLKCNKLIPIASKTCPAGKNLCYKMFMMSDLTIPVKRGCIDVCPKNSHLVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 1c, Cardiotoxin-1c.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: EGLC_NEOFI
Sequence: MQFTQLVALALALATSEAAHQGFNYGNTKSDGSAKSQSDFQAEFSTAKNLVGTSGFTSARLYTMIQGGTANTPISAIPAAVAEETSLLLGLWASGGNFANEIAALKTAIADYGDDLAKLVVGISVGSEDLYRNSVDGVKAKAGLGTNPDEIVSYINQVRSTIAGTKLSGAPIGHVDTWTAWVNGSNSAVIDACDWLGFDGYPYFQNTMANSISDAKALFDESVAKTEAVAKGKEVWITETGWPVSGNTENLAVANLANAKTYWDEVGCPLFGKTNTWWYILQDANPVTPNPSFGIVGSTLSTTPLFDLSCSASSSAAASSTAVPSASSVAGAKASGFATAAASSGAAGSAKPTFTVGKGPGGSYNGTGFWNSTSSARPSSTAISGSSSGSASGSSGSSGSGASGASGQSSSSTGSSSAPSSSNILSNAASGLSGSIFGAVVAVCLALAAL
What is the function of this protein?
Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation.  This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase (By similarity).
What are the official names of this protein?
Probable glucan endo-1,3-beta-glucosidase eglC, Endo-1,3-beta-glucanase eglC, Laminarinase eglC.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted, cell wall. Note=Covalently-linked GPI-modified cell wall protein.
Protein: ENGB_MYCMS
Sequence: MIKQASFITSSANKSNWIDDDVSEICLIGRSNVGKSSFINSLTNNNKLAKISNTPGKTRLLNFFEINKGEYRLVDAPGYGYAKVDDNLKIQFAKMMEEYFINRRNLKGVFLLLDLRHKPSNDDIMMYQFLKHYNIPVVIIGTKLDKLKKSEYVKNEKMIKETISFYQEDDFVKISNLNKTNIIKCYELIDKLLGSK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: LEG1_RHIAE
Sequence: ASAGVAVTNLNLKPGHCVEIKGSIPPDCKGFAVNLGEDASNFLLHFNARFDLHGDVNKIVCNSKEADAWGSEQREEVFPFQQGAEVMVCFEYQTQKIIIKFSSGDQFSFPVRKVLPSIPFLSLEGLAFKSITTE
What is the function of this protein?
May regulate cell apoptosis and cell differentiation.  Binds beta-galactoside and a wide array of complex carbohydrates (By similarity).
What are the official names of this protein?
Galectin-1, Gal-1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: METXS_NEIMA
Sequence: MSQNASVGIVTPQKIPFEMPLVLENGKTLPRFDLMIETYGELNAEKNNAVLICHALSGNHHVAGRHSAEDKYTGWWDNMVGPGKPIDTERFFVVGLNNLGGCDGSSGPLSINPETGREYGADFPVVTVKDWVKSQAALTDYLGIGQWAAVVGGSLGGMQALQWTISYPERVRHALVIASAPKLSTQNIAFNDVARQAILTDPDFNEGHYRSRNTVPARGLRIARMMGHITYLAEDGLGKKFGRDLRSNGYQYGYGVEFEVESYLRYQGDKFVGRFDANTYLLMTKALDYFDPAADFGNSLTRAVQDVQAKFFVASFSTDWRFAPERSHELVKALIAAQKSVQYIEVKSAHGHDAFLMEDEAYMRAVAAYMNNVYKECQQ
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAG2L_AGEOR
Sequence: MRAIISLLLISAMVFSIIEAVPEEEGLQLSEDERGGCLPHNRFCNALSDPRCCSGLRCKELSIWDSRCLG
What is the function of this protein?
Insect active toxin causing rapid but reversible paralysis in crickets.  No activity shown in mammals.  Does not show effect on mammalian voltage-gated calcium channels (By similarity).
What are the official names of this protein?
U2-agatoxin-Ao1l, U2-AGTX-Ao1l, Agel_11.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 01 (U2-agtx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERK7_DROME
Sequence: MANYQTAHAQERRIQELDQTVESIFDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKASNNLDFYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHPYVSRFQYASAEMDLHMDVVPPLKDHVRYDVDQYRNSLYELIDRETSCSNRTVSNSTPSSNRDELPKPVRVTKQARTTSAKQPTTSPAERKKEPSSVEVTQSRKNIKLLGSAHKAQSKEINHMESAITQVSIASAPPAAAPPAPAATAPAVPRKSGDKSVPKCQHNNAAVQRELAAVAAAAAVARRKKSSWQSQAQSQGKFHTEAKAHVQTAIQTQKDNIKDSPPRMIQESQSLTEAKAPIPKNRYSNKMCQEKKYKKKHHSMSCITRDTFPSETEHRQQREERAYQRQMKRELQLKESYRRRIEAESEPLKETTEQESKTIKVIEQKVCEHTEKKADESLSKDQQKDSITFGTCVRERIHHLELEMEKCTEELVDFVELNADVLNYANVSTHLKKLQRSKESDEKDEDDRRALPEGIGGPGSQNYEIFRQEQEKERQRQVQEFLARDETNEYDNLDLDHAYRAKYYTAYKEIGKELNPAPDSGGRDSGSEHSPGRDNYTTYADYFLKYTTPQQNWNDLERANGLQREHDRIYGLFWLNDRRQEEKYRRKLAQNDQEELPVHHHKACRHRHHKPNHHAPYDHMRPTEDDIQEADSLPESN
What is the function of this protein?
Atypical MAPK protein that regulates protein secretion in a kinase activity-dependent manner (PubMed:21847093, PubMed:25393288).  In response to starvation regulates protein secretion by mediating transitional endoplasmic reticulum site disassembly (PubMed:21847093).  Mediates inhibition of insulin-like peptide secretion upon disturbed ribosome biogenesis and acts as a downstream effector of TP53 (PubMed:25393288).
What are the official names of this protein?
Extracellular signal-regulated kinase 7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: PTAF_PESFW
Sequence: MSRYAILGSTGNCGTALIENVLDSSMTEVHAFCRNQEKLERLVPRVISDARVKVFVGGIGDTETLAACLHGCNAVFLCITTNDNVPGCRVAQDTALGVVKVLERSRADGFLPMPKLVLLSSATIDDVLSRNTPWVLRSILLKSASHVYEDLRKTEILLRAEQDWLTTIFIKPGALSVDIQRGHALSLTDEDSPVSYLDLAAAMIEAVNDPQGRYDMRNVGVVNTHGRANFPSGTPLCIAVGLLSHFAPFLHPYLPSGTGPR
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes (PubMed:24302702).  The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA (PubMed:24302702).  As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain (PubMed:24302702).  The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and the intermediate to release atrochrysone carboxylic acid, which is spontaneously dehydrated to form endocrocin anthrone (PubMed:24302702).  Endocrocin anthrone is then converted to endocrocin, catalyzed by the anthrone oxygenase ptaC (PubMed:24302702).  Spontaneous decarboxylation of endocrocin occurs to generate emodin (PubMed:24302702).  An O-methyltransferase (ptaH or ptaI) could methylate emodin to form physcion (PubMed:24302702).  PtaJ could then catalyze the oxidative cleavage of physcion, and rotation of the intermediate could then afford desmethylisosulochrin (PubMed:24302702).  PtaF, a putative NADH-dependent oxidoreductase, might also participate in the oxidative cleavage step (PubMed:24302702).  Desmethylisosulochrin is then transformed by another O-methyltransferase (ptaH or ptaI) to form isosulochrin (PubMed:24302702).  Chlorination of isosulochrin by ptaM in the cyclohexadienone B ring then produces chloroisosulochrin (PubMed:24302702).  PtaE is responsible for the oxidative coupling reactions of both benzophenones isosulouchrin and chloroisosulochrin to RES-1214-1 and pestheic acid respectively, regardless of chlorination.
What are the official names of this protein?
Oxidoreductase ptaF, Pestheic acid biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the avfA family.
Protein: WCWK5_STREE
Sequence: MKNMEQIDFVVTWVNDKDVDWCKRKSEFEKEYNIFQDLNSEERYREWGLMKYWFRAVEKYAPWVNKIYFITEGHVPNWLDVNHPKLVHVKHEDYIEKQFLPTFNSNVIEMNLIHLKDLSEKFVLFNDDFFINDFVKQSDFFENNLPKDTGIFSPLIPRENSLTPIILNNMEIINKYFSKKKILEQNFSKFFNIKYGKHLLKNICLLPWSDLLGFYDNHIPVSYCKSNFLEVYEKEHAIFNLTFKNKFRNKNEINHWLIRYWQLSSGNFIPRNINFGKNYAISNDPTDIINELKLSKYKIICINDGESIDNFDAVKGLMINAFEKKFPEKSSFEKK
What are the official names of this protein?
Capsular polysaccharide phosphotransferase WcwK, Stealth protein WcwK.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: RS15_PARD8
Sequence: MYLDSAKKQELFEKYGKSATNTGSAESQIALFTFRISHLTEHLKVNHKDYATERSLKMLVGKRRRLLDYLIKTDIERYRAIIKELGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TIM54_KLULA
Sequence: MWKKLPSPGWLAFGTVVTVAGSGIAYDKYEQSQIRSLYVNHVRNEMSSSLSTNVKPRKLLVLVAPPPNDYLDTSLKLWRRWIKPILHSSGLDYEIVSGTKQGEIRTEIASRVRQLRKELIEQEQQQQHDAQSKKSRSWLDWFKWCRGVSTTPDPVSEESPAASFDTRSVLGIFYHNEPQPVVTEDSLLDPSVAGGVICVGRGAYKEYIAGVHEGILGPLEEPPKVVESDASSVTDTTASAVITENPSVKEISVTQPAETAVAAATVGTTMNETGAVNTDSTPAETIPAETTPTENTPIETTPDESSEEKEGPKISKPYILPSDYANASIPAELSKPLIIDPKTGAPAFFEQPLLVVAVPNLSGFTTIPTRIARFYQKRFLCEQVSHSTLAIVEAKSRPFTTTDLDLSAYEELDWPKSWVESGKERGSEWVQPLQGDDRVLQKFRVVEPAIVPSLQLKEDQSKKQELSPENK
What is the function of this protein?
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM54.
What is the protein family that this protein belongs to?
Belongs to the TIM54 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: VF177_ASFP4
Sequence: MWKVNDQGFLNISVTGTKLNLIAITGKLGFYADPPSHLIIMPLKFFPVHKFSKNEPNKKQKRFIYF
What are the official names of this protein?
Protein I177L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus I177L family.
What are the subcellular locations of this protein?
Virion.
Protein: NCPP_YERPG
Sequence: MYHVIAATTNPAKINAITLAFDDVYGPGQYRIEGVNVDSGVPLQPIGSTETRIGARQRVKNARQVRPEADFWVGIEAGIEDNMTFAWMVVEHLQARGESRSASLMLPDIILQGIRQGRELGDEMAVLSGISNVKQQGGAIGIFTQGKLTRTSVYHQALLLALVPFHNEIYQRPSPSKPAI
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: GCSH_XANOR
Sequence: MSEIPGDLKFLKSHEWARIESNGRVTVGISDHAQGLLGDLVYVELPGVGDTVQVGNGAAVVESVKAASDVYSPVSGTVVEVNSALSDKPETINEDAYGEGWIFVVEIDDKEQLNDLLDPDDYAELLEDDEH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: Y1821_YERP3
Sequence: MINKTLLGLSLGALMFTAGSAVAADYKIDKEGQHAFIEFRIKHLGYSWLYGSFNDFDGSFTFDDKNPAADKVNVVINTNSVDTNHAERDKHLRGKSFLNVAKFPQATFESTEVKKNGDGYSVIGNLTLNGVTKPVTLESKLTGQGNDPWGGYRAGFEANGNIKLKDFNITTDLGPASQEVELILSVEGVQVK
What are the official names of this protein?
UPF0312 protein YpsIP31758_1821.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: YQFD_BACSU
Sequence: MKNKWLSFFSGKVQLELTGRGIERLLNECTRQGIPVFHVKKKKEAVSLYIQLQDVHAFRRVRSKFKCKARFINRKGFPFLLLKSKLNIGFTIGFAIFFILLFLLSNMVWKIDVTGAKPETEHQMRQHLNEIGVKKGRLQFLMMSPEKIQKSLTNGIDNITWVGVDLKGTTIHMKVVEKNEPEKEKYVSPRNIVAKKKATITRMFVQKGQPMAAIHDHVEKGQLLVSGLIGSEDHQQEVASKAEIYGETWYRSEVTVPLETLFNVYTGKVRTKHKLSFGSLAIPIWGMTFKKEELKHPKTEQEKHSLHFLGFKLPVSYVKEQTRESEEALRKYTKEEAVQEGIKLGKQDVEDKIGENGEVKSEKVLHQTVENGKVKLIILYQVIEDIVQTTPIVRETEE
What are the official names of this protein?
Uncharacterized protein YqfD.
What is the protein family that this protein belongs to?
To B.megaterium SpoIV.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PRD1_MAGO7
Sequence: MAKTSIKLNSGYEMPLVGFGIWKVPVDKTAQAVYDAIKLGYRQIDGAYDYTNSKEAGEGVRRAIEEGIVKREDLFITSKLWNNYHKHEHAIEMAKHEVDTWGIGYLDLFLIHFPISLEYISHSKMPYPCFWPDREKSRSTPLQYTPVAETWAALESLVKTDSNPDGILRSIGVANFRAQLLTDLWGSAKIKPAVNQIEHHPYLVQPQLLAFLKDHGIAITAYSSFGPQSFVELDHPRVSKVEPLFTHPTIKAIADKHGRTGAQVLLRWATQRDIVVIPKSNNVDRLKQNLDCVSFDLSDDEVKQISDLDCGVRFNDPADLSPPIYIFD
What is the function of this protein?
Pentose reductase with a broad substrate affinity involved in pentose catabolism.  Has highest reductase activities with L-arabinose and D-xylose as substrates, and displays much lower activities with D-ribose, D-galactose and D-glucose.  Has highest dehydrogenase activity with L-arabitol as substrate, followed by xylitol and D-sorbitol.  May be responsible for the first step of the L-arabinose catabolic pathway.
What are the official names of this protein?
NAD(P)H-dependent pentose reductase, PRD.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: BRO1_CANGA
Sequence: MKPSVIGLKCKDTDKVDWKRGLSSYLKRIYGSRQWKEFYDEQLCVEMDHVRNNANGELGAVTLVEQNYKYYAYLEQLYLRLGNNIGQFKLEFTWYDAEYGLVSSPTKHTQKTLVFEKSCTLYNLGVALTEVANEKINEDFKTAMVHMAKAMECFRYLSENFFNSPSADLQTENTKFLSDLSHAEAQEMFLINAINNGTSEKQASLISKLAYSGSNLYENCWEFLRTEEGGLTPYGEARWNSIVSGKHHFFRSLAAYYNALALEQNNKYGEAIAFLKLATQCLSSSLPYKYALNDNFDFDGFGETIKDKTKQLIKDNDYIFHDSIPQSVSLSSIKALDAIKAPKWEEQLKPFMEAIAHKCEKLYRGIVPMEVFEKESIYSEKKASMLRQCINDSETADMEYSSFIEFTHLPNLLSDLKRRYKSQNFSGTTDPQGDMMRDQIQSWIKSISQSKYKDPDEQLKLISSKKQEILTLLAGLPSEQKENVVKLKMALVEAAASDEKLFSLVQPYAAQLRLLKQPDELWKIFNMFSIDESNKQSLLDIDDSKNQEILAKISDIEQMAEDLRLLKEERGRTLKELKSQTNDDDITNTLLVNSKAESEELEVIFKKELDKFKPLTTRIEATIFKQESVVNEVKNELDNVFSLSGLENKTSEEEEKQKKRKEFFMQIEEAATKFLIFNNDLPKGLEFYDSLLKMSKDLAVSVKVQNNASGSDNNSNNGYVSGNVIPPSLPPQPRNVGSSIDSQFQSMNLGSVPTPQRFPQPPAPNSRPIVSMENYTSQFSVPPAHGDLPPAYNQVPLVPTRNYDQPHGSGNYPGNVSSQHPVSSSPIPGAYDQVPMVPPKQPPAEGRSQISRQEQMEREERELQRDPTAFYKKSSVFDESLYSRYSGK
What is the function of this protein?
Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles.
What are the official names of this protein?
Vacuolar protein-sorting protein BRO1, BRO domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the BRO1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome.
Protein: SC11C_HUMAN
Sequence: MVRAGAVGAHLPASGLDIFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:34388369).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (PubMed:34388369).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11C, Microsomal signal peptidase 21 kDa subunit, SPase 21 kDa subunit, SEC11 homolog C, SEC11-like protein 3, SPC21.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: PP14A_MOUSE
Sequence: MAAQRLGKRVLSKLQSPSRARGPGGSPSGLQKRHARVTVKYDRRELQRRLDVEKWIDGCLEELYRGRESDMPDEVNIDELLELDSEEERCRKIQGLLEACANPTEDFVQELLAKLRGLHKQPGFPQPSPSDDPSLSPRQDRAHTAPP
What is the function of this protein?
Inhibitor of PPP1CA.  Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction (By similarity).
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 14A, 17 kDa PKC-potentiated inhibitory protein of PP1, Protein kinase C-potentiated inhibitor protein of 17 kDa, CPI-17.
What is the protein family that this protein belongs to?
Belongs to the PP1 inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1084_SERP5
Sequence: MPSFDIVSEIDMQEVRNAVENATRDLGTRWDFRNVPASFELNEKDESIKVASESDFQVQQLLDILREKLSKRSIEGSALEIPEEMTHSGKTYSVDAKLKQGIESAQAKKLVKLIKDSKLKVQVQIQGDEVRVTGKSRDDLQGVMALVRGADLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein Spro_1084.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: LPXC_VIBPA
Sequence: MIRQRTLKEIVKTTGVGLHSGRKVTLTLRPAAANTGIIYRRTDVNPPVDFPADPASVRDTMLCTALVNDEGVRISTVEHLNAALAGMGIDNIIVEVDAPEIPIMDGSASPFVYLLQQAGIEMQNVPKRFIRIKKPVRFEDGDKWAEFVPFNGFRMDFEIDFNHPAIESDEQRLLFDFSSQGFVREISRARTFGFMRDIEYLQSQNLVLGGSFDNAIVLDDYRILNEEGLRFENEFVTHKVLDAIGDLYMCGHPIIGEFRAYKSGHGLNNQLLRAVLADQEAWEWTTFEEEVGSPVAFAEPNMVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.