PharMolix/UniProtQA huggingface dataset:
Protein: RS15_SINFN
Sequence: MSITAERKAQLIKDFATVEGDTGSPEVQVALLTERINNLTEHFKDHKKDNHSRRGLLAMVSSRRSLLDYLKKKDEARYSKLIGALGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: YL161_YEAST
Sequence: MKFQYALAKEQLGSNSRSGVKKLISKHHWLPEYYFSDLSFSVVQQWDSRAIEKTTIISCMRPANQEIYPLRHCETLRSQPCSLFSSLYARSFQSSCTLHVAEPSPGFHMYGCHT
What are the official names of this protein?
Putative uncharacterized protein YLR161W.
Protein: FBL48_ARATH
Sequence: MAKRREKRGRRRQHRSHRKIQRIIDGADFINYMPDDILHHILSFIPTDLAMRTSVLSRRWRHVWCETPCLDIKLKHGETNQTLTSYTAPIITSFKLVMDLNDNTVPQVDSWIEFALSRNVQNLSVFVRDFTYTKTYRFPDIFYISSSLKQLDVTLDFFDMIPTCAVSWKSLRNLTLRFCQIPDESMHNILSGCPILESLTLDTCRLLERLDLSKSPNLRRLDINRQYRRTGPIAIVAPHIYYLRLTYSSTPSTIVDVSSLSEANLNIISDRLLSPLTADRYQTMALEMLSKFHNVKRLTVGETILQILSLAELRGVPFPTLKVQTLTVKTEFVRSVIPGISRLLQNSPGLKKLTLHTLQLSHDIMEMHPLKGLYPDQCWRSTCEVFPTSKEIYKMLGCNDATSKLVASFMNLVLRNAKTLERMVVWLGGIYFNGDAPWFEEELFDMVETLSHNNNVSILLKQSNC
What are the official names of this protein?
Putative F-box/LRR-repeat protein At3g28410.
Protein: YLAC_LACLA
Sequence: MAITNEQVERINELARKKKAEGLSEAELEEQALLRRAYLDSVKANFRSQVETIKVIDEKTGEDVTPDKLKEIQRKNGMRD
What are the official names of this protein?
UPF0291 protein YlaC.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COG4_PONAB
Sequence: MADFDSPPKLSGVQPPSEGVGGGRCSEISAELIRSLTELQELETVYERLCGEEKVVERELDALLEQQNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRNEDYEQAAAHIHRYLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAVATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGRLYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKMSFLVTLNNVEVCSENISTLKKTLESDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVTVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL
What is the function of this protein?
Required for normal Golgi function.  Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 4, COG complex subunit 4, Component of oligomeric Golgi complex 4.
What is the protein family that this protein belongs to?
Belongs to the COG4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FB331_ARATH
Sequence: MKTRSSDAEGDSRGKMIAPVGEGNGGRKRKLVQSNEQKNDIQREEDGRAKRRIVQSSDQKNGKILRGIRGCVSPRCSAQTYQSRFSWYEQDIWTYISRFLDGKSLVKLGATNKWFYKIAMEDTVWRFACLRDLQVPVPFPVSSTWIKIYASAFDGSHSYLFRQKEKHIDWMRIGAFVLDSRTSLLTESLSGRLKFPREGTIERMLQSSGSCLINDIKSGIWIADLQLVRCPVCDLSTCDGTMQTLDARHIELFLSEGYKDGSWDYNLIGSHKLQKNASAACGAIFDLKHLKESSYSGILNLKSWTGESNDSQPKAVIAPHAVAVHTRLQENEGILVKYHTMKAGTDGDIVSIRISQQLL
What is the function of this protein?
Regulates tapetum degeneration and pollen maturation during anther development.
What are the official names of this protein?
Probable F-box protein At3g61730, Protein RFM, Reduced male fertility protein.
Protein: ATPB2_BURP0
Sequence: MADPQATNGTGAACAERDASDVGDARDEGAGRVVAVRGAVIDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPLLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVLVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSDPASGSAEPQGARHGR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNH_FRAP2
Sequence: MGIFTKKNNVIAYTDGACKGNPGIGGWGAILSYNGVDKEISGAEKDTTNNRMELMAAIKTLQALKRKCDITIYTDSKYLQNGINQWLANWKANGWKTAAKKEVKNKDLWQELDSLTTKHNVTWSWVKGHSGNQGNEKADELANKAIAELTGK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PER58_ARATH
Sequence: MGLSKTIPLVLLPILMFGVLSNAQLTSDFYSTTCPNVTAIARGLIERASRNDVRLTAKVMRLHFHDCFVNGCDGSVLLDAAPADGVEGEKEAFQNAGSLDGFEVIDDIKTALENVCPGVVSCADILAIAAEISVALAGGPSLDVLLGRRDGRTAIRADAVAALPLGPDSLEILTSKFSVHNLDTTDLVALSGAHTFGRVQCGVINNRLHNFSGNSGQSDPSIEPEFLQTLRRQCPQGGDLTARANLDPTSPDSFDNDYFKNLQNNRGVIESDQILFSSTGAPTVSLVNRFAENQNEFFTNFARSMIKMGNVRILTGREGEIRRDCRRVN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 58, Atperox P58, ATP42.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM6_SACD2
Sequence: MTASNKQAVKAYLLNLQDKICQVLAAVDGKETFVEDSWQRPEGGGGRSRVLTNGAVIEKGGVNFSHVHGSSMPASATAHRPELAGRSFEAMGVSLVIHPNNPHVPTSHANVRFFIAEKEGAEPVWWFGGGYDLTPYYGNDEDCRHWHNTAKAACAPFGEDKYPRYKKWCDEYFYLKHRDEPRGVGGLFFDDLNELGFDQSFAFMQAVGDSYTQAYVPIVERRKDEPYNQAQRDFQLYRRGRYVEFNLVYDRGTLFGLQTGGRTESILMSLPPLVRWEYDWQPQPNTPEARLYEHYLQPQDWAE
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_AGRVS
Sequence: MTTENNKPPVKTANQRGAARLAAVQALYQMDIGGTGVLEVVAEYETHRLGQEIDGETYLKADASWFRSIVAGVVRDQTKIDPLIRQALQDDWSLARVDSTVRAILRAGTFELLERKDVPIAVIVTEYVEIAHAFFQEDEPKLVNAVLDRIAKQVRVPAVK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: DAPK3_MOUSE
Sequence: MSTFRQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKVRRREDGARKPERRRLRAARLREYSLKSHSSMPRNTSYASFERFSRVLEDVAAAEQGLRELQRGRRQCRERVCALRAAAEQREARCRDGSAGLGRDLRRLRTELGRTEALRTRAQEEARAALLGAGGLKRRLCRLENRYDALAAQVAAEVQFVRDLVRALEQERLQAECGVR
What is the function of this protein?
Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization.  Regulates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths signal, depending on the cellular setting.  Involved in formation of promyelocytic leukemia protein nuclear body (PML-NB).  Involved in apoptosis involving PAWR which mediates cytoplasmic relocation; in vitro phosphorylates PAWR (By similarity).  Phosphorylates MYL12B in non-muscle cells leading to reorganization of actin cytoskeleton such as in regulation of cell polarity and cell migration.  Positively regulates canonical Wnt/beta-catenin signaling through interaction with NLK and TCF7L2; disrupts the NLK-TCF7L2 complex thereby influencing the phosphorylation of TCF7L2 by NLK.  Phosphorylates STAT3 and enhances its transcriptional activity.  Enhances transcription from AR-responsive promoters in a hormone- and kinase-dependent manner.  Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis (By similarity).  Phosphorylates RPL13A on 'Ser-77' upon interferon-gamma activation which is causing RPL13A release from the ribosome, RPL13A association with the GAIT complex and its subsequent involvement in transcript-selective translation inhibition.
What are the official names of this protein?
Death-associated protein kinase 3, DAP kinase 3, DAP-like kinase, Dlk, MYPT1 kinase, ZIP-kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere. Cytoplasm. Note=Predominantly localized to the nucleus. Relocates to the cytoplasm on binding PAWR where the complex appears to interact with actin filaments. Associated with the centrosomes throughout the mitotic cell cycle, with the centromeres from prophase to anaphase and with the contractile ring during cytokinesis (By similarity).
Protein: Y021_TREPA
Sequence: MDDARYAEWSASLVQLPDTHFFDLMRLYLGVLKTPFHKQRLVQQLSAFLQRKSIQNAVVQMLDELDLLFISVVMCVPRATLELLTIFF
What are the official names of this protein?
Uncharacterized protein TP_0021.
Protein: TOR2A_HUMAN
Sequence: MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHLAGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRVHHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGSSWVVYGTNYRKAIFIFISNTGGKQINQVALEAWRSRRDREEILLQELEPVISRAVLDNPHHGFSNSGIMEERLLDAVVPFLPLQRHHVRHCVLNELAQLGLEPRDEVVQAVLDSTTFFPEDEQLFSSNGCKTVASRIAFFL
What are the official names of this protein?
Torsin-2A, Torsin family 2 member A, Torsin-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. Torsin subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: NTPP_HYPNA
Sequence: MSLAVTLASTSKSRRALLAAAGVEADGVAPNVDEESFRNTMRANKLPVREQAMQLAELKAMRVSAKRPGLVIGGDQMLALGDEAFDKPADLEAAKNHLRQLSGKSHTLETAIVICEDGAPIWRHLARPKLTMRPLTEDFIETYVSSCGDALLSTVGAYQLEGPGAQLFTRIEGDYFSILGLPLLPLLDYLRIRKVLPT
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_CORGL
Sequence: MSAKIGVITFPGTLDDVDAARAARIAGAEVISLWHADEDLKGVDAVVVPGGFSYGDYLRTGAISALAPVMQSVIEQAGKGMPVLGICNGFQILTEARLLPGALTRNKGLHFHCVDAHLVVENNTTAWTNTLEKGQQILIPAKHGEGRFQADAETIAQLEGEGRVVFRYTDNFNGSVNDIAGITNETGRIVGLMPHPEHAVEKLTGPSIDGLELFLSAVGTIAA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPR2_BOVIN
Sequence: MLPSWTIGLLLLATVRGKEICYEPFGCFSDEKPWTGILQRPLKLFPWSPEDIDAHFLLYTNENPNNYQRINITDLATVRASNFQLDRKTRFVIHGFIDDGDSGWPTDLCKKMFKVEKVNCICVDWEHGAWTKYTQAVHNTRVVGAEIAFFIQGLSTELGYGPENVHLIGHSLGAQLAAEAGRRLGGQVGRITGLDPAQPCFEGTPEEVRLDPSDAMFVDVIHTDSASIIPFLSLGIRQKVGHLDFYPNGGKEMPGCQKNILSTIIDINGIWQGIQDFVACSHLRSYKYYSSSILNPDGFLGYPCASYEEFQEGGCFPCPAGGCPKMGHYADQFQGKTSAVGQTFFLNTGSSGNFTSWRYRVSVTLAGTKKVRGSIRIALYGSNGNSKQYQIFKGSLQPNASHTHDIDVDLNVGKVQKVKFLWNNNVINLFWPKLGASRVTVQGGEDRTEYNFCSNDTMRENALQTLYPC
What is the function of this protein?
Lipase that primarily hydrolyzes triglycerides and galactosylglycerides.  In neonates, may play a major role in pancreatic digestion of dietary fats such as milk fat globules enriched in long-chain triglycerides.  Hydrolyzes short-, medium- and long-chain fatty acyls in triglycerides without apparent positional specificity.  Can completely deacylate triacylglycerols.  When the liver matures and bile salt synthesis increases, likely functions mainly as a galactolipase and monoacylglycerol lipase.  Hydrolyzes monogalactosyldiglycerols (MGDG) and digalactosyldiacylglycerols (DGDG) present in a plant-based diet, releasing long-chain polyunsaturated fatty acids.  Hydrolyzes medium- and long-chain fatty acyls in galactolipids.  May act together with LIPF to hydrolyze partially digested triglycerides.  Hydrolyzes long-chain monoglycerides with high efficiency (By similarity).  In cytotoxic T cells, contributes to perforin-dependent cell lysis, but is unlikely to mediate direct cytotoxicity (By similarity).  Also has low phospholipase activity (By similarity).  In neurons, required for the localization of the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) to neurite tips through acyl chain remodeling of membrane phospholipids (By similarity).  The resulting OPPC-rich lipid membrane domain recruits the t-SNARE protein STX4 by selectively interacting with the STX4 transmembrane domain and this promotes surface expression of the dopamine transporter SLC6A3/DAT at neurite tips by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane (By similarity).
What are the official names of this protein?
Pancreatic lipase-related protein 2, PL-RP2, Cytotoxic T lymphocyte lipase, Galactolipase, Triacylglycerol lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Zymogen granule membrane; Peripheral membrane protein. Cell projection, neuron projection. Note=Localizes to neurite tips in neuronal cells.
Protein: PDRP_BACC7
Sequence: MDNKIVYVVSDSVGETADLVVRAAMGQFPFAPDIRRVPYVEDTGTLKEVISIAKSNQALICFTLVKPDMRQYLVTEAAKEGVEAYDIIGPLIDQIEEITGQVPRYEPGVVRRLDEEYFKKIEAIEFAVKYDDGRDARGILKADIVLIGISRTSKTPLSQYLAHNKRLKVANVPLVPEVDPPEELYQVAKEKCFGLKITPEKLNHIRKERLKSLGLSDGATYANINRIKEEIDHFENVVSKINCQVIDVSNKAIEETANIIVNAVQNQKMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: CNU_ECOL5
Sequence: MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAADHRRAELVSGGRLFDLGQVPKSVWHYVQ
What is the function of this protein?
Modifies the set of genes regulated by H-NS; Hha and cnu (YdgT) increase the number of genes bound by H-NS/StpA and may also modulate the oligomerization of the H-NS/StpA-complex on DNA.  The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC.
What are the official names of this protein?
OriC-binding nucleoid-associated protein, H-NS/StpA-binding protein 2, Transcription modulator YdgT.
What is the protein family that this protein belongs to?
Belongs to the Hha/YmoA/Cnu family.
Protein: RRAAH_XANAC
Sequence: MTWTTPDLCDRYPDAMIAEPLFRHFGGRTAFAGPLATVRCFEDNSRVRELAATPGDGRVLVVDGQGSLKHALLGDQIAANAVANGWAGVLIHGCVRDVEILATLPLGVLALAACPRRTERRDLGDVDVPVNFAGVPFVPGHWLYADANGVLVAPQPLALDGAGGSI
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: CDPF1_DANRE
Sequence: MDLTEGSALGVFSCQLCEVSSPYSFYGQKPPNTRAIVLLEECFGIKDPFSPEREKFLILGSKCSLCSKTVCVGTVRRSCDSQSEAKL
What are the official names of this protein?
Cysteine-rich DPF motif domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CDPF1 family.
Protein: ASPP1_MOUSE
Sequence: MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGGCHLAEVWRGSERPIPYDHMMYEHLQKWGPRREEVKFFLRHEDSPTESSEQGARQTQEQRTQRSVVNVPGEKRTENGVGNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSVSENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSYNGRLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSTGGFPLPGDPVKPQSLTIASSAAHGRSKSANDGNWPPLKQNSASVKSTQMTGDWKDSGMEGTLKQGAISSQPLPLSALGATEKLGIEIGKGPPPIPGVGKPLPPSYGTYPSSGPLGPGSTSSLERRKEGSLPRPGAGPPSRQKPAPLPPASNAPQPGSSQQIQQRISVPPSPTYPPAGPPAFPTGDGKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPPAHGTLNKSVKAVYGKPVLPSGSASPSPLPFLHGSLGTGTAQPQPPSDSAEKEPEQEGPSVPGEGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFVGTLADMDNGNTNANGNLDEPFPPRPTAPLPEELAPSSDANDNELPSPEPEELICPQTTHQTAEPTEDNNNNVAPVPSTEQIPSPVAEAPSEEDQVPPAPLSPVIHPPAASASKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGTVYALWDYEAQNSDELSFHEGDAITILRRKDENETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA
What is the function of this protein?
Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53 (By similarity).  Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo (By similarity).
What are the official names of this protein?
Apoptosis-stimulating of p53 protein 1, Protein phosphatase 1 regulatory subunit 13B.
What is the protein family that this protein belongs to?
Belongs to the ASPP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic (By similarity). Some fraction is nuclear.
Protein: SYS_HYPNA
Sequence: MFDIRAIRDNPDAFRNAWNRRKSGLGSVVDDILKLDAQWREATTAKQDAESARNANSKLIGQAKAKKDEAEAARLMALVAEAKTTMEQAGEAEDNARKALDDLLMGLPNLPLDEVPEGSDEHGNVEQHTWGEPKLINDPKDHADLGEALKGQGGFPMMDFEAAARMSGARFVALRGKLTRLERALANFMLDLQTTEHGYEEMSVPVLVRDQALYGTGQLPKFAEDLFRTTVDHWLTPTAEVSLTNLVREQILDAAQLPLRFTAHTPCFRSEAGSAGRDTKGMIRQHQFNKVELVSIVANEAEGLAELERMTGCAEEVLKRLELPFRRMLLCTGDMGAGARKTYDLEVWLPSQNTYREISSCSYCGDFQARRMDARYRPEPKAKPEYVHTLNGSGLAVGRTLVAVLENYQNADGSITVPKALVPYMGGVEVIN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_EBLV1
Sequence: MDVNKVVFKVHNQLVSVRPEVISDQYEYKYPAIKDKKKPSITLGKDPDLKTAYKSILSGMNAAKLDPDDVCSYLAGAMVLFEGICPEDWTSYGINIAKKGDKITPATLVDIHRTNTEGNWAQTGGQDLTRDPTTPEHASLVGLLLCLYRLSKIVGQNTGNYKTNVADRMEQIFETAPFVKIVEHHTLMTTHKMCANWSTIPNFRFLAGAYDMFFARIEHLYSAIRVGTVVTAYEDCSGLVSFTGFIKQINLTAREAILYFFHKNFEEEIKRMFEPGQETAVPHSYFIHFRSLGLSGKSPYSSNAVGHVFNLIHFVGCYMGQIRSLNATVIQSCAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKELQDYEAAESTKVDVALADDGTVNSDDEDFFSGDTRSPEAVYTRIMMNGGRLKRSHIKRYVSVSANHQARPNSFAEFLNKTYSSDPR
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: PLSX_BACC4
Sequence: MKIAIDAMGGDHAPKAVVLGAMKAIKEYSDLHITLVGKEEEIRQYLTSDERITILHTDEKIESTEEPVRAVRRKKQASMVLAAQQVKDGEADACISAGSTGALMAAGLFVVGRMEGIERPALSPTMPTVDGKGFVMLDVGANVDAKPIHLYQYAVMGSVYAEKVRGIENPRVGLLNVGTEDEKGNELSKQVFAMLKDAPINFVGNVESRDLLQGVADVVVCDGFTGNVALKSLEGTALALFSMLKEQLMSSFTSKLAAAVLKPKLMVLKDKMDYSEYGGAALFGLKAPVIKAHGSSNDQSIFSAIRQTREMVAKEVIPTISSVMEKESLQ
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.