PharMolix/UniProtQA huggingface dataset:
Protein: RL1_SINMW
Sequence: MAKIAKRVQKSREGVDPAKLYGLTEAVTMIKERATAKFDETIEVAMNLGVDPRHADQMVRGVVNLPNGTGRSVRVAVFARGAKADEAKAAGADVVGAEELVEIVQGGKIDFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTMDVAGAVKASKGGAVEFRVEKAGIVHAGIGKASFDAKALEENIRAFADAVIKAKPTGAKGNYVKRVAVSSTMGPGLKIDPATISAA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: NU4M_LATCH
Sequence: MLKVLMPTIMLILTTWLTKPAWLWPTMTTNSLLVATISLTWLKWDSESGWKSLNSSMATDPLSTPLLILTCWLLPLMILASQNHMFMEPLNRQRSFISLLISLQTFLIMAFGATEIILFYIMFEATLIPTLIIITRWGNQTERLNAGTYFLFYTVMGSLPLLVALLMTQNNLGTLSMPLIQHMYQMKLHTHGDMMWWTACLLAFLVKMPLYGVHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRLIMMLAPMTKTLAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVGHMGLVAAGILTQTPWGFTGATVLMIAHGLTSSALFCLANTNYERTHSRTMILARGMQVILPLMTFWWLMMNLANLALPPSTNLMGELLIITMTFNWSNWTLTMTGLGMLITAIYSLHMFLTTQRGLMTNHIISIEPSHTREHLLMTMHALPMLLLILKPELIWGWSYX
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: URE3_YERE8
Sequence: MQLTPREVEKLMIYTLSDVAFKRKARGLKLNYPEAVSIITVTAMEGARDGKSVEDVMKEASKVLTKDDVMDGVADLIPNVQVEAIFTDGSRLVTVHDPIK
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB5A_DICDI
Sequence: MNNNNKIFQFKLVLLGEAAVGKSSLVLRFVRGHFLDYQESTIGAAFLAQTVCLNDTTVKFEIWDTAGQERYHTLAPMYYRGAQAAIVVYDIRSEDSFERAIKWVKELQRQGSPNIVIALAGNKLDLAAKRKVETAEAQQYAEENGLLFMETSAKTSQNVNELFVEIAKKLPKTPTTRPGSGRVAIAPIDNGNTGKKNKCCN
What is the function of this protein?
Required for the fusion of plasma membranes and early endosomes.
What are the official names of this protein?
Ras-related protein Rab-5A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Endosome membrane; Lipid-anchor.
Protein: HVM21_MOUSE
Sequence: EVKLVESGGGLVQPGGSLRLSCATSGFTFSDFYMEWVRQSPGKRLEWIAASRNKANDYTTEYSASVKGRFIVSRDTSQSILYLQMNALRAEDTAIYYCARYYGSSYWYFDVWGAGTTVTVSS
What are the official names of this protein?
Ig heavy chain V region M511.
Protein: YAJC_ECOL6
Sequence: MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVLPKGTMKAL
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: BPHC3_RHOGO
Sequence: MTVTPRLAHFVLQTNQLPAMTQWYIDVLGAHVVYENPAMCFLTTDEEHHRVALFGPPGGGLPERTPATVGLAHTAFTFPTLGDLIDKYLQLRDKGIEPRVPVQHGVTTSLYYRDPDGNMVELQIDNFATPEESTDYMHGEEYTTDTIGPSFNPLALAEAYKAGVPESELTTRAWALKTEQINVMERMLTP
What are the official names of this protein?
Biphenyl-2,3-diol 1,2-dioxygenase 3, 2,3-dihydroxybiphenyl dioxygenase III, DHBD III, 23OHBP oxygenase III, Biphenyl-2,3-diol 1,2-dioxygenase III.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
Protein: HRCA_CLOAB
Sequence: MEMEERKLKILQAIINDYINNGEPVGSRTIAKKYNLGISSATIRNEMADLEEMGYIEQLHTSSGRKPSDKGYRLYVDRLMEIPSMSVEEEMLIKAKIIDSALYEIDKLVKQAMSLVSEMTKLTCVVKSLSARKSYIKSISLINIEPNMILCVFITDSGMIKNSIIRVKSNIENSSLERIANILNSKLKGLTIEQINLEVINNIKKDLREYGHIFDCIMPNLYDILREADSTEVYKEGTMNIFNYPEFKDIEKAKEFLSVIDDRRILDTLFNASGGVTVNIGNENSIKEARDFSVVSSVYKYNGRPLGTIGIIGPTRIPYSKVIKVIMEVVDQINNNLDKMNNS
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: SYFA_ERWT9
Sequence: MSHLADLVERALAAINDAQDVAALDNVRVEYLGKKGHLTLQMTTLRELPAEERPAAGAVINEAKQQVQDALNAQKNALESAVMNARLAQETIDVSLPGRRIENGGLHPVTRTIDRIETFFGELGFSVETGPEIEDDYHNFDALNIPAHHPARADHDTFWFDATRLLRTQTSGVQIRTMKNQQPPIRVIAPGRVYRNDYDQTHTPMFHQMEGLIVDKNISFTNLKGTLHDFLNNFFEDDMQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLSNAGIDPEVYSGFAFGMGMERLTMLRYGVTDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRQ_BRUO2
Sequence: MAAATGTRKKKTPRPGQWKLWLLYTAGFVPAVWTFYLGATGQLGADPVKTFEHLLGLWALRFLILTLLVTPIRDLTGITLLRYRRALGLLAFYYALMHFTTYMVLDQGLNLSAIITDIVRRPFITIGMISLALLVPLALTSNNWSIRKLGRRWSSLHKLVYIAIAGSAVHFLMSVKSWPAEPVIYAAIVAALLLWRLARPYLRTRKPALRPRGEAIALRK
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TFB1M_BOVIN
Sequence: MASSRTLGTFRLPPLPTIREIIKLFRLQAVKQLSQNFLLDLRLTDKIVRKAGNLTNAYVYEVGPGPGGITRSILNAGVAELLVVEKDSRFIPGLQMLSDAAPGKLRIVHGDVLTFKIERAFPESLKRQWEDDPPNVHIIGNLPFSVSTPLIIKWLENVSQRNGPFAYGRTRMMLTFQKEVAERLTATTGSKQRSRLSIMAQYLCDVQHILTIPGQAFVPKPEVDSGVVHFTPLTRPRIKQPFKLVEKVVQNAFQFRRKYCHRGLGMLFPEARRLESTGKLLELADVDPTLRPTQLTVSHFKSLCDVYRKMCDEDPHLFAYNFREELRQKSKKEDDKQSCRL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop.  Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM.  Stimulates transcription independently of the methyltransferase activity (By similarity).
What are the official names of this protein?
Mitochondrial dimethyladenosine transferase 1, Mitochondrial 12S rRNA dimethylase 1, Mitochondrial transcription factor B1, mtTFB1, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y271_METJA
Sequence: MDLKSNIKLILATDLLAVLILSLFIKNFKMVLAFLLAVFVIWLFIDKNNINERLYENLLAMSVGFIEGILIFLGIIYNEVFLDITLGIFAILILIVMGILFPKYKLIFEVFDEFVEHLKQKSGFLTLISIFGMLLTIYVFLLILPSKEFCINAVDIIRTIMLVITANMFIIEFYTFKKFS
What are the official names of this protein?
Uncharacterized protein MJ0271.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y898_FRAT1
Sequence: MQTIEIGNKAELQACKFLHTQALEILAHNFKALPYGEIDIIALDKDTLIFIEVKYRSKTKFAQAEEMLTYSKQQKLVNSASIYLQHNPQYQDYQCRFDLIAINESNINWIKNAFGVI
What are the official names of this protein?
UPF0102 protein FTF0898c.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: GRPE_ECO24
Sequence: MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_CORA7
Sequence: MSDPQAALRASWKAVVSDLLAQSEQPNSDVPNFSHSQRLNLQLVEPIMIGDGYALIAAPHENAKTVIETELGEYITRALSQHMGRPCSLAVTIAAPPQPAPQEEPPAPAPQRPIQTEAPEHGMGHQTQAFQQPTQSTQPAPASQPETPNHHQPRSWEAAHSPASLDELAQHYSEQQSTAPSGYPEATGARIPREEPAHNPNREKSLNPKHTFENFVIGSSNRFANGAAVAVAENPARAYNPLFIWGGSGLGKTHLLHAAGNYAQVLHPGLRVKYVSSEEFTNDYINSLRDDRQESFKRRYRNLDILMVDDIQFLEGKESTQEEFFHTFNALHQANKQIILSSDRPPKQLTTLEDRLRTRFEGGLITDIQPPDLETRIAILMKKASADGTDVDRSVLELIASRFESSIRELEGALIRVSAYSSLVNEPISLEMAEIALHDLAPDSADRQITAAAIIEVTADYFNIDVDTLRGSGKKRAVAHARQLAMYLCRELTELSLPKIGDQFGGKDHTTVIYADRKIRKEMTENRNTYDEIQALTQRVKNHNQR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COLL1_MIMIV
Sequence: MSRITCPITDCKCKCNKNNCVYCVMGRQGLPGPKGSSGNSIYVGTGVPSPFLGNNGDLYIDSSTGLLYAKVNGVWVPQGSLKGDPGASGSKGEKGDKGSSGEAGLKGEQGTKGEQGDQGEQGDKGDKGDKGDVGAKGDQGDKGDQGDVGAKGDQGDKGDQGDVGAKGDQGDKGDKGDQGDKGDVGDPGVKGDKGDTGDKGDKGDKGDKGQNGSEILFGLGIPSPDLGEDGDVYIDTLTGNVYQKIGGVWVLETNIKGEKGDQGDKGDTGSKGDQGDKGDQGDKGDQGDKGDVGDKGNKGDTGSKGDVGDKGDVGDKGDKGDTGDKGDKGDTGDKGDKGDVGDKGDKGDVGDKGDVGDKGDVGDKGDKGDTGDKGDKGDIGDKGDKGDIGDKGDKGDIGDKGDKGDVGDKGDKGDKGDIGDKGDKGDIGDKGDKGDKGDKGENGSGILFGLGIPSPDLGEDGDIYIDTLTGNVYQKIGGVWVLETSIKGEKGDKGDTGDKGDTGDKGDTGDKGDTGDKGDTGDKGDVGDKGDVGDKGDVGDKGDVGDKGDKGDIGDKGDKGDLGDKGDKGDVGDKGDVGDKGDKGDIGDKGDKGDLGDKGDKGDVGDKGDKGDVGDKGDKGDIGDKGDKGDVGDKGDKGDIGDKGDKGDKGDVGSKGDKGDKGDVGDKGDKGDVGSKGDKGDKGDKGDVGPVGASILFGAGVPSPTTGENGDSYIDNSTGVFYLKINDVWVPQTNIKGDKGDKGDKGDKGDKGDTGDVGLKGDTGTPGSGPIIPYSSGLTPVALAVVAVAGGGIADTGASYDFGVSSPSVTLVGVNLDFTGPVQGLLPNMAWSAPRDTVITSLATAFQVSVAISAVLEPIFLRTQVYRELAANPGVFEPLAGAIVEFDVASSALISVGTVFRGIVTGLSIPVNAGDRLIVFANTRTTSLISVGTVTGFISSGLALA
What is the function of this protein?
May participate in the formation of a layer of cross-linked glycosylated fibrils at the viral surface thus giving it a hairy-like appearance.
What are the official names of this protein?
Collagen-like protein 1.
What are the subcellular locations of this protein?
Virion.
Protein: YESM_BACSU
Sequence: MKKRVAGWYRRMKIKDKLFVFLSLIMAVSFLFVYSGVQYAFHVYDEQIYRKSSEVLRMSSERIEDELKKIEDVSYEIITDEQIQRILSMQNRDDTYDQYQMKQELWDQLAGYASDEKYIDSIHVIDARGSEYSAGSSSSDLLQQEQEEVFKRAKAKSGRNLWMTLGGSDPVLISARQIRSYHQLSLNGLGMVLIQVNVKQMIRDVPKDWGDSVGDIMIADQGGNLVYTAHASAHVPEAAKETLKHPGYDLIKKNGKRYFISYLQSSYQNWSYYNVIPFDQMFAKISFMKTVIGTCFLLFFCVVLLFGRKIANSITEPIEQLVTAMKSVQHSGIEAGVSLSLPEHTQDEAGMLNRHFTVMMKRINELMEENVEKQLIIKETELKALQAQINPHFLYNTLESINWLAKANQQKQISKMVESLGFLLRNSIHMKKDIVTIQEEADIVRHYMTIQRFRFEERLKFTLDIDDEVKHCLIPKLTLQPLAENAIQYALEPFTRPCAIRIQAKKAKGCVCITVEDNGPGMDGRILESTGGRGIGLWNIRERISLTFGEPYGLRIHSEHEKGTRIVITIPCRNEVV
What is the function of this protein?
Member of the two-component regulatory system YesM/YesN.  Probably activates YesN by phosphorylation.
What are the official names of this protein?
Sensor histidine kinase YesM.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIX1_DROME
Sequence: MVYPEEPFWVLPTVTGFYEDRDYRVNVVEALQEFWQMKQSRGAELKNGALVIYESIPSNSQPYICFVTLPGGSCFGSFQNCPTKAEARRSSAKIALMNSVFNEHPSRRISDEFIQKAVQDARTSFKGTSQINEGTESGIGAFRFMLEANKGRTMLEFQELMTVFQLLHWNGSLKAMRERHCSRQEVVAHYSNRSLDDEMRSQMALDWIAREHDNPGVIRRELVLAERELETFRMAGRELRFPKEKKDILMIAHNQLGGSALNSATIDD
What is the function of this protein?
Component of the Fat (ft) signaling pathway that functions in normal development of various organs such as the wing and leg (PubMed:19710173, PubMed:21379328).  In developing imaginal disks, involved in regulating both the protein levels and apical localization of ft and ds (PubMed:19710173).  Involved in establishing planar cell polarity (PCP) along the anterior-posterior axis of the wing (the early Fz signaling event), probably by acting upstream of ds and ft to regulate Fz activity (PubMed:21379328).
What are the official names of this protein?
Protein limb expression 1 homolog, lowfat.
What is the protein family that this protein belongs to?
Belongs to the LIX1 family.
What are the subcellular locations of this protein?
Apical cell membrane; Peripheral membrane protein. Cytoplasm. Note=In wing imaginal disks, strong cytoplasmic expression in the wing pouch but in regions of the wing hinge preferentially expressed in the sub-apical membrane.
Protein: RS9_RICRO
Sequence: MPELKIKTEKVEKQLTKEPLVLKTPKEKIDNLGKFYATGKRKNAIARVWLKVGKGKIVVNKKTIAQYFPSETYVKTILQPFVLTKTIDQYDIICTVRGGGISGQKGAILHGISKALDKSAPDFRAILRKGGLLTRDSRVVERKKYGQRKARKKTQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: U119B_HUMAN
Sequence: MSGSNPKAAAAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHAADDGVGAAVTEQELLALDTIRPEHVLRLSRVTENYLCKPEDNIYSIDFTRFKIRDLETGTVLFEIAKPCVSDQEEDEEEGGGDVDISAGRFVRYQFTPAFLRLRTVGATVEFTVGDKPVSNFRMIERHYFREHLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ
What is the function of this protein?
Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization.  Binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane.  Does not bind all myristoylated proteins.  Probably plays a role in trafficking proteins in photoreceptor cells.
What are the official names of this protein?
Protein unc-119 homolog B.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Enriched at the transition zone and extended into the proximal end of the cilium.
Protein: RISB_ECOL5
Sequence: MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CHM4B_DANRE
Sequence: MSLFGKMFGSGGKGGKSASPQEAIQRLRETEEMLTKKQEFLEKKIEQELVTAKKNGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENAHTNTEVIKNMGYAAKAMKAAHDNMDIDKVDELMQDIIEQQELAQEISDAISKPVGFGEEFDEDELLAELEELEQEELDKNLLEIGDNVPLPNVPSTSLPSRPAKKKEEEDEDDMKDLEAWAAN
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 4b, Chromatin-modifying protein 4b, CHMP4b.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein. Midbody.
Protein: SPEE_PROMS
Sequence: MTDITTWIDEYHKGSRFGLNGKILFKKTSKYQEIIVIENEYYGKALMLDGCWMTSLKDEKYYHECLVHPALSSIDEKSNVLIIGGGDGGTVRECVKYSKISKIDLVEIDEEVIKISKKFLKEIAGEAWNDKRLEIHIDDGVKWVEKTKDNFYDVIFIDCSDPSEFSNLLFSHSFYKECERILAPSGILATQSESPESFKNIHINILKSLKNIFKVSETMYSFVPIYPSGIWSWTFASSEDLSLSKQNYDEVVKIEKGCEIWNLNFQNAAFKMMPNKIVKELDS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3097_LEGPC
Sequence: MSQLIDRRQNAGKKSTVNRQRFLRRYKSQIKKAVSEAVGKRSITEIDQGEQITIPAKDIYEPQFHRGHGGHIERVLPGNDNFIAGDRIKRPGGGAGGAGGNASDSGEGEDNFVFELSREEFLELYFEDLELPDLVKKELARISTYKTVRAGVTTSGIPNNINVLRSMKQATGRRVALASPYKKRLKEAEEELERLKQLTNPDKIDLLKLERDIEFFKKKIQTVPFIDTIDLRYNHRVRVPSPSTQAVMFCVMDVSGSMDEAKKDIAKRFFILLYMFLTKNYEKIELVFIRHHTSAKEVNEEEFFYSRETGGTVVSSALELLNTIIEARYPPQAWNIYVAQASDGDNWNADSPYCQELLQEKIMPLLQYFAYIEIMPRHHQSLWEVYQQVKERYPNFAMENIDNVADIYPVFRELFKRKTV
What are the official names of this protein?
UPF0229 protein LPC_3097.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: TPIS_YEAST
Sequence: MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIINSRN
What are the official names of this protein?
Triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
Protein: RENT1_YEAST
Sequence: MVGSGSHTPYDISNSPSDVNVQPATQLNSTLVEDDDVDNQLFEEAQVTETGFRSPSASDNSCAYCGIDSAKCVIKCNSCKKWFCNTKNGTSSSHIVNHLVLSHHNVVSLHPDSDLGDTVLECYNCGRKNVFLLGFVSAKSEAVVVLLCRIPCAQTKNANWDTDQWQPLIEDRQLLSWVAEQPTEEEKLKARLITPSQISKLEAKWRSNKDATINDIDAPEEQEAIPPLLLRYQDAYEYQRSYGPLIKLEADYDKQLKESQALEHISVSWSLALNNRHLASFTLSTFESNELKVAIGDEMILWYSGMQHPDWEGRGYIVRLPNSFQDTFTLELKPSKTPPPTHLTTGFTAEFIWKGTSYDRMQDALKKFAIDKKSISGYLYYKILGHQVVDISFDVPLPKEFSIPNFAQLNSSQSNAVSHVLQRPLSLIQGPPGTGKTVTSATIVYHLSKIHKDRILVCAPSNVAVDHLAAKLRDLGLKVVRLTAKSREDVESSVSNLALHNLVGRGAKGELKNLLKLKDEVGELSASDTKRFVKLVRKTEAEILNKADVVCCTCVGAGDKRLDTKFRTVLIDESTQASEPECLIPIVKGAKQVILVGDHQQLGPVILERKAADAGLKQSLFERLISLGHVPIRLEVQYRMNPYLSEFPSNMFYEGSLQNGVTIEQRTVPNSKFPWPIRGIPMMFWANYGREEISANGTSFLNRIEAMNCERIITKLFRDGVKPEQIGVITPYEGQRAYILQYMQMNGSLDKDLYIKVEVASVDAFQGREKDYIILSCVRANEQQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSLARNTLWNHLLIHFREKGCLVEGTLDNLQLCTVQLVRPQPRKTERPMNAQFNVESEMGDFPKFQDFDAQSMVSFSGQIGDFGNAFVDNTELSSYINNEYWNFENFKSAFSQKQNRNEIDDRNLYQEEASHLNSNFARELQREEQKHELSKDFSNLGI
What is the function of this protein?
RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs (PubMed:8896465, PubMed:30218034).  Also capable of unwinding double-stranded DNA and translocating on single-stranded DNA (PubMed:30218034).
What are the official names of this protein?
ATP-dependent helicase NAM7, Nonsense-mediated mRNA decay protein 1, Nuclear accommodation of mitochondria 7 protein, Up-frameshift suppressor 1.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with polysomes.
Protein: Y2958_SHEPA
Sequence: MKVWVDADACPGVIKEILFRVADRAKVEVTLVANHWMRIPPSPYINLKTVSSGFDVADDEIVKLLSAGDLVITADIPLASEVIDKGGFALNPRGELYTEQNIKSILNMRDFMDTMRASGVQTGGPAAIGASEKQAFGNQLDRFITKNHKPS
What are the official names of this protein?
UPF0178 protein Spea_2958.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: NQRA_HAHCH
Sequence: MIKIKKGLDLPIAGAPAQVIEDGKPVTQVALIGFDYNGMKPTMEVKVGDRVKCGQLLFTDKKTEGVRYTSPASGVVSAVNRGERRVFQSIVIDIEGDDSEQFAQFSPEELPNLSREQVVENLVGSGEWTALRTRPYSKAPAIDAEPHSIFVTAMDSHPLSADPAVIINEAKADFKNGLVVLGKLTRGKVFVCARAGVNYDLPSGSNAVQEQFDGPHPAGLAGTHIHYLDPVNASKFVWTIGYQDVIAIGRLFTSGRKSVERVVALAGPMVSKPRLLRTRTGASLAQLTEGELKSSDVRLISGSVLGGRNAKGNVSFLGRFANQISCLEEGYKREFMGWLSPGSNKYSLLNIYLSKLNPGKLFNFTTTTNGSERAMVPVGSYEKVMPLDILPTQLLRSLVVGDTEMAQKLGCLELDEEDLSLCTFVCPGKYEYGPILRDSLTRIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: LIPB_PROMT
Sequence: MDKKLHFVSPETGPNSNLDLTPQLAQSSSAFLFEPKNIVPFETALGWQKNFQKNLIEQPFSPQAVWLLEHFSCFTMGRGSDKKNLLFEENNSPLPVFSIERGGEVTHHMPGQIVGYLVLNLSLHKKDLSWYLRELEQVLIDVLDLLGMEGKRVDGLTGVWCEDKKVGSIGIGCKRWVTQHGFSLNVDCDLIGFEKIIPCGLDKVKVGKLSDWIPGIKVCDVTPLLRESVKRRFKLNWEK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.