PharMolix/UniProtQA huggingface dataset:
Protein: S26A2_HUMAN
Sequence: MSSESKEQHNVSPRDSAEGNDSYPSGIHLELQRESSTDFKQFETNDQCRPYHRILIERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEMSVQLSHDPLELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCKKEEENLLFYSVYEAMAFAEVSKNQKGVCVPNGLSLSSD
What is the function of this protein?
Sulfate transporter.  May play a role in endochondral bone formation.
What are the official names of this protein?
Sulfate transporter, Diastrophic dysplasia protein, Solute carrier family 26 member 2.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
Protein: MURQ_YERPE
Sequence: MSLGALISESRNPATMELDKLSTLAMLTCINDEDRKVPDAIRLVLPAVAQAVDLAADALKQGGRLIYLGAGTSGRLGVLDASECPPTFGVPHGMVIGLIAGGPGALLKAVEGAEDDIALGMRDLQDLQLTATDMVVGLAASGRTPYVIGALRYARELGCPTAAISCNPDSPIAQEAQVAISPVVGPEALTGSTRMKSGTAQKLVLNMLSTGAMVKLGKVYQNLMVDVKATNVKLVDRACRIVVEATGVSRAEAEHALRQTDFEVKPAILMLLKGVSAEQARQDLRQHHGYLRAAL
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: TECT1_HUMAN
Sequence: MRPRGLPPLLVVLLGCWASVSAQTDATPAVTTEGLNSTEAALATFGTFPSTRPPGTPRAPGPSSGPRPTPVTDVAVLCVCDLSPAQCDINCCCDPDCSSVDFSVFSACSVPVVTGDSQFCSQKAVIYSLNFTANPPQRVFELVDQINPSIFCIHITNYKPALSFINPEVPDENNFDTLMKTSDGFTLNAESYVSFTTKLDIPTAAKYEYGVPLQTSDSFLRFPSSLTSSLCTDNNPAAFLVNQAVKCTRKINLEQCEEIEALSMAFYSSPEILRVPDSRKKVPITVQSIVIQSLNKTLTRREDTDVLQPTLVNAGHFSLCVNVVLEVKYSLTYTDAGEVTKADLSFVLGTVSSVVVPLQQKFEIHFLQENTQPVPLSGNPGYVVGLPLAAGFQPHKGSGIIQTTNRYGQLTILHSTTEQDCLALEGVRTPVLFGYTMQSGCKLRLTGALPCQLVAQKVKSLLWGQGFPDYVAPFGNSQAQDMLDWVPIHFITQSFNRKDSCQLPGALVIEVKWTKYGSLLNPQAKIVNVTANLISSSFPEANSGNERTILISTAVTFVDVSAPAEAGFRAPPAINARLPFNFFFPFV
What is the function of this protein?
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube.  During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation.  Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals.  Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity).
What are the official names of this protein?
Tectonic-1.
What is the protein family that this protein belongs to?
Belongs to the tectonic family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Secreted. Note=Despite the presence of a signal sequence, the full-length protein might not be secreted. Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: RL361_HAEDU
Sequence: MKVRASVKKLCRNCKVVKREGVVRVICTDPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SYDP_ESCF3
Sequence: MDELTAQALRDFTTRYCDAWHEKHHSWPLSEELYGVPSPCIISTTSDAVYWQPQPFVGEQNLAAVERAFDIVLQPAIQTFYTTQFAGDMHAQFAEHTLTLLQTWSEDDFRRVQENLIGHLVTQKRLKLSPTLFIATLENELDVISLCNLSGEVCKETLGTRNRQVLAPSLAEFLKQLNPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: NQOR_ECOL6
Sequence: MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: RIMP_SHEPA
Sequence: MATLERKLVEMLKAPVEALGHKLWGLEYIQAGKHSILRLYIDNEKGIFIEDCAEASRQVSAVMDVEDPISTEYTLEVSSPGVDRPLFTAEQYQAYIGETVKVQLTMPVAGSRNLKGTVTGVDGQMLNLSVDGNELIVALDNIRKGNLIAKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RQCH_STRP2
Sequence: MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQSHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEMTVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGSTYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEKLSAFRNFFNQETKPCLTETSFSPVPFANQAGEPFANLSDLLDTYYKNKAERDRVKQQASELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILDNYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVETVLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQNEELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQVDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS
What is the function of this protein?
Plays a significant role in virulence (PubMed:11580843).  Recombinant protein binds to immobilized human fibronectin; binding is saturable and competed by heparin.  Purified protein inhibits binding of whole cells to fibronectin (By similarity).
What are the official names of this protein?
Rqc2 homolog RqcH, RqcH, Pneumonococcal adherence and virulence protein A.
What is the protein family that this protein belongs to?
Belongs to the NEMF family.
What are the subcellular locations of this protein?
Secreted, capsule. Cell surface. Cytoplasm. Note=Found on the cell surface in the region of the capsule in capsulated bacteria (NCTC 10319 and R36A).
Protein: RS6_POLNA
Sequence: MRHYEIVLLIHPDQSEQVPAMLERYKGMITAGGGTVHRVEDWGRRQLVYLIQKLAKAHYLCINIEASQAVMEEIEHAFKFNDAVLRHLTVVKKKAETGPSLMMRNVEREEARKTQQQEFAA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MURE_CLOTE
Sequence: MKLKEVLKKLEYNILNGNIEIDIENIQYDSRNIKKNDIFFAIQGYSTDGHKFIESAIEKGAKVIVFDKGFENENMYKDITFIKVKNSRKALAVAASNYYGNPKDKLKLIGVTGTNGKTTSTFMIKSILEEAGFKVGLMGTILNYIGDRKIYAQRTTPESLEIHKLFKDMVDSGVDYCVMEVSSHSLYLDRVYGIEFNEGIFTNLTQDHLDFHKTFENYYNSKLMLFKNSINSVINIDDNYGERILKEIEEKTFTYSIKKYSDLKAESVRLHSRGGEFTVDFKGNKEKINIHIPGEYNVSNALGSILACVNEGISLKVIKRGLEKLSGVPGRCEIVTMGYNLGYDVIVDYAHTPDGLDNVLRTARDFTKGKLISVYGCGGDRDRAKRPIMGRIGTELSDLAILTSDNPRTEEPFSIIDDIVKGVTKDNYIIVQSRREAIKKAMTIAKKDDVIVVAGKGHEDYQILKDKTIHFDEREVIKEIIEELY
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE1B_ORYSJ
Sequence: MEVEEAAYRTVWSEPPKRPAGRTKFRETRHPVYRGVRRRGGRPGAAGRWVCEVRVPGARGSRLWLGTFATAEAAARAHDAAALALRGRAACLNFADSAWRMPPVPASAALAGARGVRDAVAVAVEAFQRQSAAPSSPAETFANDGDEEEDNKDVLPVAAAEVFDAGAFELDDGFRFGGMDAGSYYASLAQGLLVEPPAAGAWWEDGELAGSDMPLWSY
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.  Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription.  Confers resistance to high salt, cold and drought stress.
What are the official names of this protein?
Dehydration-responsive element-binding protein 1B, Protein DREB1B.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPP_STRGC
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILADNSGKTVEQIHADAERDYWMSAEETLAYGFIDEIMANNNLS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M2_I96A2
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGIVHLILWIIDRLFFKCIYRIFKHGLKRGPSTEGVPESMREEYREEQQNAVDADEGHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: YIHI_AERHH
Sequence: MSAKQPNRKPAGKRKESDASAQEGRERKRAAKRKGLKAGSRQQVEQAGKKSGTKQAKDPRIGSRKPVALIVEEKSSKPVAPKQIKEKKLVMTPEQELASIENDDRLNDLLDRLDAGETLEATEQAWVDQRVDRYQELMDELGIIDTDDDEDEADFDEADFDEPGQPASEEELWDRFTQVDYQPEPKPEPKKK
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: UVRC_AYWBP
Sequence: MSILLEKIKTLPPNPGCYLFKNTKDTIIYVGKAKNLKKRVQSYFTKRNNLKTAMLIEETQDFFYIITNNEQEALILEANLIKTHTPKYNFKLLDDKTYPYIEITKEKHPQLKISRFKQIPPGKIIFGPYPNLKSTKETLKLLHLLYPLRRCQLASKKPCLHFHINQCLGACAGKTINYKPNIDAITKFLKGNIKDILKKLHHLMQKASEKMFYEKAQEYRDIIDSIKQTTKKQLISNQKLKNCDIFAYAFNQDQIAIQILKIRQGNIVDSYRSVFSYVGFVCENILTYLNCYYQKNIKPDIIITGKNQDENILQQTITNQTLLEQILQTKVNIYHKGDKKKLFLLALKNAQNDLSHNNLIYQSKDQKIQEALNKLAIIFNKDIKRIDVFDNSQLFGKAFVAARIVFNHFEFDKKLYRTFHIKGELPNEYQAFEETLTRCYNKGKEAENDATDLILVDGSLVQLRQSQKTLKKLGYEIPLGALQKNNKHQLTHLVTFQEKLMLEQDPNLFHFLKSLSEEVHRFAVSFHRKTKKKLDYKTTLSNIKGVGVVRKKAILNHFESLEAIKKATLQDFQKIGINQKLFLLIKKSL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CADH_MEDSA
Sequence: MGSIEAAERTTVGLAAKDPSGILTPYTYTLRNTGPDDVYIKIHYCGVCHSDLHQIKNDLGMSNYPMVPGHEVVGEVLEVGSNVTRFKVGEIVGVGLLVGCCKSCRACDSEIEQYCNKKIWSYNDVYTDGKITQGGFAESTVVEQKFVVKIPEGLAPEQVAPLLCAGVTVYSPLSHFGLKTPGLRGGILGLGGVGHMGVKVAKALGHHVTVISSSDKKKKEALEDLGADNYLVSSDTVGMQEAADSLDYIIDTVPVGHPLEPYLSLLKIDGKLILMGVINTPLQFVTPMVMLGRKSITGSFVGSVKETEEMLEFWKEKGLTSMIEIVTMDYINKAFERLEKNDVRYRFVVDVKGSKFEE
What is the function of this protein?
This protein catalyzes the final step in a branch of phenylpropanoid synthesis specific for production of lignin monomers.  It acts on coniferyl-, sinapyl-, 4-coumaryl- and cinnamyl-alcohol.
What are the official names of this protein?
Probable cinnamyl alcohol dehydrogenase, CAD.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: ZN329_HUMAN
Sequence: MRLKMTTRNFPEREVPCDVEVERFTREVPCLSSLGDGWDCENQEGHLRQSALTLEKPGTQEAICEYPGFGEHLIASSDLPPSQRVLATNGFHAPDSNVSGLDCDPALPSYPKSYADKRTGDSDACGKGFNHSMEVIHGRNPVREKPYKYPESVKSFNHFTSLGHQKIMKRGKKSYEGKNFENIFTLSSSLNENQRNLPGEKQYRCTECGKCFKRNSSLVLHHRTHTGEKPYTCNECGKSFSKNYNLIVHQRIHTGEKPYECSKCGKAFSDGSALTQHQRIHTGEKPYECLECGKTFNRNSSLILHQRTHTGEKPYRCNECGKPFTDISHLTVHLRIHTGEKPYECSKCGKAFRDGSYLTQHERTHTGEKPFECAECGKSFNRNSHLIVHQKIHSGEKPYECKECGKTFIESAYLIRHQRIHTGEKPYGCNQCQKLFRNIAGLIRHQRTHTGEKPYECNQCGKAFRDSSCLTKHQRIHTKETPYQCPECGKSFKQNSHLAVHQRLHSREGPSRCPQCGKMFQKSSSLVRHQRAHLGEQPMET
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 329.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHAM_LACLA
Sequence: MTYGIVIVSHSPEIASGLKKLIREVAKNISLTAIGGLENGEIGTSFDRVMNAIEENEADNLLTFFDLGSARMNLDLVSEMTDKELTIFNVPLIEGAYTASALLEAGATFEAIKEQLEKMLIEK
What is the function of this protein?
Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone.  DhaM serves as the phosphoryl donor.  Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.
What are the official names of this protein?
PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit DhaM, PTS system EIIA component, Phosphotransferase enzyme IIA component.
Protein: FPG_POLNS
Sequence: MPELPEVEVTRLGIAPHLEGRKVSAVKIIDGRLRWPVPANLTKTLPGQTVNGIERRGKYLLLEMDTGYLLIHLGMTGTLRVLPSSDPLKTHDRVTLEFGKLSLRLHDPRKFGAVLWHPKSKGPIKKFILLQKLGVEPFSSEFSGELGAEILYQTSRKRSVAVKQFLLAGQAVVGVGNIYCSESLFEAGIHPAKAAGKLTRPQCSRLAKAVRSILKKAIEAGGSSLKDFVNSDGDPGHFMVQTKVYDRKGLPCKVCKTPISQMVQGQRTTYFCSQCQKR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: BE_THET8
Sequence: MARFALVLHAHLPYVRAHGMWPFGEETLYEAMAETYLPLIRVLERLRAEGVEAPFTLGITPILAEQLADARIKEGFWAYAKDRLERAQGDYQRYRGTALEASARHQVAFWELTLDHFQRLSGDLVAAFRKAEEGGQVELITSNATHGYSPLLGYDEALWAQIKTGVSTYRRHFAKDPTGFWLPEMAYRPKGPWKPPVEGPPEGVRPGVDELLMRAGIRYTFVDAHLVQGGEPLSPYGEAALGPVESQEATYHVHELESGLRVLARNPETTLQVWSADYGYPGEGLYREFHRKDPLSGLHHWRVTHRKADLAEKAPYDPEAAFAKTEEHARHFVGLLERLAGRHPEGVILSPYDAELFGHWWYEGVAWLEAVLRLLAQNPKVRPVTAREAVQGPAVRTALPEGSWGRGGDHRVWLNEKTLDYWEKVYRAEGAMREAARRGVLPEGVLRQAMRELLLLEASDWPFLMETGQAEAYARERYEEHARAFFHLLKGASPEELRALEERDNPFPEADPRLYLFREA
What is the function of this protein?
Catalyzes the formation of branch points in alpha-glucans by cleavage of an alpha-1,4 glycosidic bond and subsequent transfer of the cleaved-off oligosaccharide to a new alpha-1,6 position.  The branch chain-length distribution of the reaction products shows degree of polymerization (DP) of 3 to 13, with two local maxima at DP 7 and DP 11.  Exhibits an alpha-retaining catalytic mechanism.  Is involved in glycogen biosynthesis.  Shows a secondary activity, i. e.  the hydrolysis of the substrate, being 4% of the total activity.  Can use amylose as substrate but not alpha-1,4-linked oligosaccharides of 2-7 glucose residues, beta-cyclodextrin, 6-O-glucosyl-beta-cyclodextrin and 6-O-maltosyl-beta-cyclodextrin.  Is not able to branch amylopectin further, it only hydrolyzes amylopectin.  Thus, displays preference for linear and long substrates (amylose) over branched structures (amylopectin).
What are the official names of this protein?
1,4-alpha-glucan branching enzyme TTHA1902, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 57 family.
Protein: A28_FOWPN
Sequence: MDALFVFIIILATAVICLFLFQAYTIYDNYHNIIEFNEKYGGLEYSRSPGGLYIDKRVFDPNDSETDPKAKWRCVNYNNNQYASASKFGYLATSSRNPVLFTNLEDCVYYNYTRGEIGTIWNPCAEYGEGSAECSTLKSHL
What is the function of this protein?
Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).
What are the official names of this protein?
Envelope protein A28 homolog, Protein FPV192.
What is the protein family that this protein belongs to?
Belongs to the poxviridae A28 protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Note=Component of the intracellular mature virion (IMV) membrane.
Protein: GCH1_STRT2
Sequence: MENQEKVEQAVYQLLEALGENPEREGLLDTPKRVAKMYAEMFSGLNEDPKDQFTAVFSEVHDEVVLVKDIPFYSMCEHHLVPFYGMAHVAYLPSGDKVTGLSKLARAVEVAARRPQLQERLTDQVATALEEALNPRGVFVMVEAEHMCMTMRGIKKPGSKTITTVAKGIYKEDREERKEILSLMRDF
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: TBA_PLAFK
Sequence: MREVISIHVGQAGIQVGNACWELFCLEHGIQPDGQMPSDKASRANDDAFNTFFSETGAGKHVPRCVFVDLEPTVVDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEVIDVCLDRIRKLADNCTGLQGFLMFSAVGGGTGSGFGCLMLERLSVDYGKKSKLNFCCWPSPQVSTAVVEPYNSVLSTHSLLEHTDVAIMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPVVSAEKAYHEQLSVSEITNSAFEPANMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRMDQKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGIESNEAEGEDEGYEADY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: VE1_HPV47
Sequence: MADSKGSTSKEGFGDWCILEADCSDVEDDLGQLFERDTDSDISDLLDNCDLDQGNSRELFHQQECKQSEEQLQKLKRKYLSPKAVAQLSPRLESISLSPQQKSKRRLFAEQDSGLELTFNNEAEDVTPEVEVPAIDSRPDDDEGGSGDVDIHYTALLRSSNQKATLLAKFKQAFGVGFNELTRQFKSYKTCCNHWVVSVYAVHDDLFESSKQLLQQHCDYIWVRGIDAMSLYLLCFKAGKNRGTVHKLITTMLNVHEQQILSEPPKLRNTAAALFWYKGCMGPGVFTHGPYPEWIAQLTILGHKSAEASAFDLSVMVQWAFDNNLFEEADIAYGYARLAPEDSNAVAWLAHNNQAKYVRECAMMVRYYKKGQMRDMSMSEWIYTRIHEVEGEGQWSSIVKFLRYQEINFISFLAALKDLLHSVPKRNCILFHGPPNTGKSSFGMSLIKVLRGRVLSFVNSKSQFWLQPLGECKIALLDDVTDPCWVYMDQYLRNGLDGHFVSLDCKYRAPMQTKFPPLILTSNINVHAETNYRYLHSRIKGFEFKNPFPMKADNTPQFELTDQSWKSFFTRLWTHLDLSDQEDEGEHGESQRAFQCSARTANEHL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: QUEC_STAA2
Sequence: MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHTPLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.