PharMolix/UniProtQA huggingface dataset:
Protein: PGK_ONYPE
Sequence: MTKSLTNMNITNKKVLLRADLNVPLENSVITDDNRIKAILPTLKYLVQQKAKVIIFSHLGRVKTEADKAHFSLQVVAEKIAFYLQQKLKFVPETQGNTLNQAVGQMLPGDVLVVQNTRFEDVPFKKESKNDPELGKYWASLGDVFVNDAFGTCHRTHASNVGIATYIKEKCFGFLVEKEISFLKKIVQTPQRPLVAVLGGSKVSDKIGVIRSLLQKVDVLLIGGGMSYTCLKAKCFNIGTSLLEADKIPLVKELLASPEGKKIVLPKDFVCGKEFSPTTQAAVYSYDNISDDVMGLDIGPQTIELFKTYLQTAQTVVWNGPVGVFEFEQFSKGTKALAETISNLSPNTTTIIGGGDSAAAVFKFGLDQNFSHISTGGGAFLEFLEGKPMPGLACMEKL
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG5_ASPTN
Sequence: MEHQATLNDIQKAVWDGRLPLQITLSPSESRSYDKTDPYLISYPRISYLPSLLPRLHAFFSSSLIEPTSKPHDGWFSFEGVPLKWHLPVGLLYDLYAGADPASKGSGPASDDETAEFPLPWRLVVQFSDWPDEELVRLDADGMVMHDAFINSVKEADFMRNGTAKGIMTLSKEDSSGLWKSVQDVDLPSFQRISNILLPPPNQPFRNVPIRFFLPLPPDSGAPSLKVVQSPLPPTLPPSSMAASQAAISRTPQPQTLGTALHALLPNLFPSRRTPVLAKPVLHGAVLPMSAPVEEVVRSSAYGDGWVYIVVRMMG
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production.  Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function.  The atg12-atg5 conjugate acts as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: CPFC_LACLS
Sequence: MDKKKGILLVALGTPRSCETEDVREYLKEFLGDPLVIQKPRWLWLPILNGIILKVRPQKSAEMYKQIWTDEGSPLMSYTIAQTEQLQGLREDFDVRFAMTYGEPRIDKVIREMKESGVEDITVLPLYPQYSLTTVEPIIQQVKKIDDKINVIRDFHQIESYTDLLAESIREKWQANHYDKLILSYHGIPLSYVTKKKDAYEAQCIETTRLVVEKLGLKEEEYEHTYQSKFGPEKWLEPATIDRIAELPKEDTKKVLICSPAFVADCLETLFELEIENKEVFVENGGETFDFVHPFNDSLEFTKVLSEVIEKNKVEVEV
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCT1_ARATH
Sequence: MEPSKQEVPKLMETPPNISNDSSATEKGEATRQQQLPNNRYALTVDEVIEQHIGALGFAQILHALLVSIAWIFDAQTTLISIFSDAQPAARLLATGAIVEGASLCGLASGEWEWIGPKSDTVVSEWNLICQHKFLVAVPSTLFFIGSLFGSGVYGYLADSWFGRKKTLLLSCVLTFVTAFAISFSPNVWVYAFLRFANGFFRSGIGSCCIVLATEIVGKKWRGQVGQYGFFFFTLGFLSLPLMAYLERKSWRNLYRIISFLPLGYAVCLLPFAYESPRWLLVKGRNKEAMVVLKKLARLNGKQLPADLSLVDPIPERDDQTSSSEKFWKTKWAVKRIIMVMMAGFGSGFVYYGIQLNAENLNFNLYLTVAVNALMEFPAVFIGSFLLGVMNRRPLFSNSSYLAGFACLLCAVLSIHRVIRAISVAKWLQLAVEAVGFMASSTAYDVLYVYCVELFPTNVRNTAVSLLRQAFMLGASAAPLLVALGRESAMMSFIVFGVASVLSGIVSLWLRETRNAPLYETLAQQGKAEEIENETIMIT
What is the function of this protein?
High affinity carnitine transporter involved in the active cellular uptake of carnitine.  Also transports organic cations.  Regulates lateral root development.
What are the official names of this protein?
Organic cation/carnitine transporter 1, AtOCT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSLU_MARMM
Sequence: MTDFTPREIVSELDRFIVGQADAKKAVAIALRNRWRRRQLDDALAEEVTPKNILMIGPTGVGKTEISRRLAKLAGAPFIKVEATKFTEVGYVGRDVEQIARDLVEIAINIVRETKREDVKAKAHAAAENRVVDALVGPNSSEATRESFRKRLLAGELDDKDVEIQLADSGAGMQMLDIPGMPTGGAGVINIGDILGKGFGQKTKTVRMKVKDAYEPLINEEADKLLDDSQITADAIKLAENDGIVFLDEIDKIAARSDARGGDVSREGVQRDLLPLIEGTTVATKHGSIKTDHILFIASGAFHVAKPSDMLPELQGRLPIRVELSALSEADLKRILVEPEASLIKQYVGLLATEGVSLDFTDDAIDALAKLAADFNASVENIGARRLQTVMEKLVEDISFTASDRSGQEITIDADYVAEHVGTLAKNADLSKFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_AGRRK
Sequence: MQRITITIDDDLLETIDKISEQRGYASRSETLRDLVRDAVTREQAAVDSETKCYATLTYVYEHETRDLSRRLTTTQHHHHDLSVSTLHVHVDGHDCLEVSVLKGTVGEIKSFADSVVTQRGVRFGNLHLIPSEHGPHDHGPHSHD
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: GAG_MLVBM
Sequence: MGQTVTTPLSLTLEHWGDVQRIASNQSVGVKKRRWVTFCSAEWPTFGVGWPQDGTFNLDIILQVKSKVFSPGPHGHPDQVPYIVTWEAIAYEPPPWVKPFVSPKLSLSPTAPILPSGPSTQPPPRSALYPAFTPSIKPRPSKPQVLSDDGGPLIDLLTEDPPPYGEQGPSSPDGDGDREEATSTSEIPAPSPMVSRLRGKRDPPAADSTTSRAFPLRLGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLTTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVNSAFPLERPDWDYTTPEGRNHLVLYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPAIGRKLERLEDLKSKTLGDLVREAEKIFNKRETPEEREERIRRETEEKEERRRAGDEQREKERDRRRQREMSKLLATVVTGQRQDRQGGERRRPQLDKDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLDD
What is the function of this protein?
Involved in the packaging and encapsidation of two copies of the genome.  Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome.  This binding is dependent on genome dimerization.
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p30]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p10-Gag]: Virion. SUBCELLULAR LOCATION: [RNA-binding phosphoprotein p12]: Host cytoplasm. Note=Localizes to the host cytoplasm early in infection and binds to the mitotic chromosomes later on.
Protein: TYSY_RALSO
Sequence: MQPYLDLMRHVHEHGTDKADRTGTGTRSVFGHQMRFDLQQGFPLVTTKKVHIKSIVYELLWFLQGATNVRWLRENGVTIWDEWADAEGELGPIYGYQWRSWPTPSGEHIDQIAELIAQIKRNPDSRRLIVSAWNVADIPRMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHMIAQQTGLDVGDFVWTGGDCHLYNNHFEQVETQLARTPLPLPKLHIKRKPDSIFDYRYEDFEIVGYESHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_THEAB
Sequence: MAVLTMKQLLEAGVHFGHRTQRWNPKMKEYIFGARKGIYIIDLQKTSKLLDEAYNFVRDKAAEGGTILFVGTKKQAQQVIKQEAERCGAFYVNHRWLGGLLTNFETIRKRIDKLIELEEMEANGEFDHLPKKEQSRLRRILEKLRKNLGGLKNMTSLPDVIYIVDPRKERNAVYEANLLKIPTVAIVDTNCDPDEIDYIIPGNDDAIRAIQLITSKIADAYLEGREGVSFGSEEAEENNQKEDNEEIFEIEDVDESEEM
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: FAH1_ARATH
Sequence: MVAQGFTVDLKKPLVFQVGHLGEDYEEWVHQPIATKEGPRFFQSDFWEFLTLTVWWAVPVIWLPVVVWCISRSVSMGCSLPEIVPIVVMGIFIWTFFEYVLHRFVFHIKTKSYWGNTAHYLIHGCHHKHPMDHLRLVFPPTATAILCFPFWNIAKAISTPSTAPALFGGGMLGYVMYDVTHYYLHHAQPTRPVTKNLKKYHLNHHFRIQDKGFGITSSLWDIVFGTLPTTKAPRKEQ
What is the function of this protein?
Fatty acid 2-hydroxylase involved in the alpha-hydroxylation of sphingolipid-associated very long-chain fatty acids (VLCFA).  Probably involved in the resistance response to oxidative stress.
What are the official names of this protein?
Dihydroceramide fatty acyl 2-hydroxylase FAH1, Fatty acid 2-hydroxylase 1, AtFAH1.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
Protein: ENOPH_SORMK
Sequence: MAPVKVVLLDIEGTVCPISFVKDVLFPYALEALPGTLKAKWDSPGFASYRAAFPAEHAGSQETLAAHVRDLMSKDLKISYLKSLQGYLWETGYRNGELKAPLFADVAPQLARWREHNGAKVMIYSSGSVPAQKLLFGHTNGEPSDILPWLSDFFDTVNAGPKQEKASYEKIAAKHQEYPIGEWLFLSDNVKEVEAAKQAGMQSYIVDRPGNAELSEEARKEHRVVKSFEEIGDL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PURT_PSEAE
Sequence: MTRIGTPLSPSATRVLLCGSGELGKEVAIELQRLGCEVIAVDRYGNAPAMQVAHRSHVISMLDGAALRAVIEQEKPHYIVPEIEAIATATLVELEAEGYTVVPTARAAQLTMNREGIRRLAAEELGLPTSPYHFADTFEDYRRGVERVGYPCVVKPIMSSSGKGQSVLKGPDDLQAAWDYAQEGGRAGKGRVIVEGFIDFDYEITLLTVRHVDGTTFCAPIGHRQVKGDYHESWQPQAMSAQALAESERVARAVTEALGGRGLFGVELFVKGDQVWFSEVSPRPHDTGLVTLISQDLSEFALHARAILGLPIPVIRQLGPSASAVILVEGKSRQVAFANLGAALSEADTALRLFGKPEVDGQRRMGVALARDESIDAARAKATRAAQAVRVEL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: FKBX_SHIFL
Sequence: MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASLSEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFTAMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA
What is the function of this protein?
PPIases accelerate the folding of proteins.  Substrate specificity carried out with 'Suc-Ala-Xaa-Pro-Phe-4-nitroanilide', where Xaa is the amino acid tested, was found to be Phe > Leu >> Ile > Lys = Ala > Trp > His >> Gln (By similarity).
What are the official names of this protein?
FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
Protein: GLGC_CORGB
Sequence: MVKGVKGRPNVLAIVLAGGEGKRLFPLTEDRAKPAVPFGGTYRLIDFVLSNLVNSGFLKIAVLTQYKSHSLDRHISLSWNVSGPTGQYIASVPAQQRLGKRWFTGSADAILQSLNLISDEKPDYVIVFGADHVYRMDPSQMLDEHIASGRAVSVAGIRVPREEATAFGCIQSDDDGNITEFLEKPADPPGTPDDPDMTYASMGNYIFTTEALIQALKDDENNENSDHDMGGDIIPYFVSRNDAHVYDFSGNIVPGATERDKGYWRDVGTIDAFYECHMDLISVHPIFNLYNSEWPIHTTSEGNLPPAKFVRGGIAQSSMVSSGSIISAGTVRNSVLSNNVVVEEGATVEGAVLMPGVRIGKGAVVRHAILDKNVVVRDGELIGVDHVRDAQRFKVSAGGVVVVGKNQVV
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: GLMM_STRPI
Sequence: MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKVFVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASHNPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKYEGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGSTHPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLAQNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMDYNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAIKVIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: PDUH_CITFR
Sequence: MESNLTTPAIVIFATAGCTDVWGDVLLGIEEEGIPFVIQESPSTDVIHNAWLAACQSPLLVGIGCSREKLVVHYKNLPTSAPLFTLTYQQDNHARRSIGNNAARLVKGIPFRECHS
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
Propanediol dehydratase-reactivating factor small subunit, DDR small subunit, Propanediol utilization protein PduH.
What is the protein family that this protein belongs to?
Belongs to the DdrB/PduH family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: CYSN_VIBC3
Sequence: MNNAVKEQLAELGIEGYLNQHQHKSLLRFLTCGSVDDGKSTLIGRLLHDSKQIYEDQLAAVHNDSQRVGTTGSRPDLALLVDGLQAEREQGITIDVAYRYFSTQKRKFIIADTPGHEQYTRNMATGASTCDLAVILIDARKGVLDQTRRHSFISNLLGLKHFIVAVNKMDLVDYSQDRFEQIRAEYLEFSKHLQGETEIQIIPLSALEGDNVVEKSRLMDWYQGPSLLELLENVDIDRDKSSGAFRFPVQYVNRPNLDFRGFAGTIASGVVKVGDKIKALPSGKTSTVTRIVTFDGDLPQAQAGLAVTLTLADEIDISRGDLIVLESAQVDSTNHLLADVVWMTEQPLQVGRDYDIKIAGKKTVGQVKAVRHQYDINNLSTYHAESLPLNGIGLCEWTFTQTVALDKYLDCADTGGFIIIDRLTNVTVGAGLVRDSLQNITGQTESFSAFELELNALVRKHFPHWQAIDLSRLGKA
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: YDM7_SCHPO
Sequence: MLMLDGGSTAILPKLPESISESRLWTSEALVRYPEIVVKHHEEFLKVCDIISTFTYQLDASIYDEKVEGVPLKQVYANSIGLPVYAREHLGLPNKYIALCLGSHAATIPGCMEYKMIYDKPTDFEMLYNFHKNRIEAIQASNPKAFEKIDFIAFESLPHVTEAEVVCQLIQDMKGWSKRCWITCTCPERSTIERVSSIISKILSINHDSIWGIGVNCFHLSLLEPIAKMLSSLLPSNITAILYPDGRGLYQNPDGTFSPGSTDHPAPSPEEWSTITAKYSNLHNGNLILGGCCETNYNHLSLLREKTK
What are the official names of this protein?
Uncharacterized protein C57A7.07c.
Protein: ASMT_MACMU
Sequence: MGSSGDDGYRLLNEYTNGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVEASSHGTELLLDTCVSLKLLKVETRAGKAFYQNTELSSAYLTRVSPTSQCNLLKYMGRTSYGCWGHLADAVREGKNQYLQTFGVPAEDLFKAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSGFPLMCDLGGGPGALAKECLSLYPGCKVTVFDVPEVVRTAKQHFSFPEEEEIHLQEGDFFKDPLPEADLYILARILHDWADGKCSHLLERVYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILVRK
What is the function of this protein?
Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine).
What are the official names of this protein?
Acetylserotonin O-methyltransferase, Hydroxyindole O-methyltransferase, HIOMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: EAF2_RAT
Sequence: MNGPAGLAYLDRRERILKLGESFEKQPRCAFHTVRYDFKPASVDASCEGNLEVGKGEQVTITLPNIEGSTPPVTVFKGSKRPYLKECILIINHDTGECRLEKLSSNITVKKTRGEGSSKIQCRLEQQQQQMWNPPRTSNLVQHSPSEDKLSPTSLMDDIERELKAEASLMDQMSSCDSSSDSRSSSSSSSEDSSSDSEDDDRSSPSGPRRYSSEHPSVSAGPQYRTSDADTTCNRLYDNSALLMSTLRSDLQLSESDSDSED
What is the function of this protein?
Acts as a transcriptional transactivator of ELL, ELL2 and TCEA1 elongation activities (By similarity).  Potent inducer of apoptosis in prostatic and non-prostatic cell lines.
What are the official names of this protein?
ELL-associated factor 2, Testosterone-regulated apoptosis inducer and tumor suppressor protein.
What is the protein family that this protein belongs to?
Belongs to the EAF family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: TIG_RHOOB
Sequence: MKSTVEQLSPTRVRINVEVPFEELKPDFDKAYKALAQQIRLPGFRPGKAPAKLLEARVGRGAVLEQVVNDALPSRYSEAVTSASVKAIGQPEIEITKIEDGELLEFTAEVDVRPEITLPDYSELSVTVDPIEITDEAVEEQLLSLRQRFGTLTGVERAVEDGDFISIDLSATVDGEAVPEATASGLSHEVGSGQLIEGLDEAVVGVKAGESKEFTSTLVAGDHAGKEAVVTVTVGTVKERELPAEDDEFAQLASEFDTLDELKADLRERVGRVRKVEQAGQIRDKVLETLLETVEVPLPEAVVKAEVDAALHDAVHGLDHDEDALNKLLEEQGTSREEFDKDAKDSAERSVKTQLLLDAIADASDVTVGQDELTERILFQAQRYGMAPEQFIQQIQQAGQLGAVFADVRRGKALAGVVEQATVTDTSGASVDTAELFGNGEADTEEAASTDEVASDSAEGEDQK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PSIE_HAEI8
Sequence: MEESLELEKLPRIITDVLKIVLCTALIALAIVLIIALVKITYTLSMMVLNTSSVVPYDVAEQAVMFFLYFGFIGLIVQYFKSGYHFPLRYFIYAGITAMLRLIIVNHESSVDTILFAGAILIMVIALCLVLYSNKLKNI
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS20_AERS4
Sequence: MANIKSAKKRAIQSEKRRQHNASRRSMTRTYLKKVIAAIASGDKAAAVAAFATAQPIMDRMATKGLIHKNKAARHKSRLSAQIKAMA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RL29_GRAFK
Sequence: MKQSEVKELSVAELQEELGKSRKAYSDLKMAHAVSPLENPIQLRTVRRDVARLATELTKREQQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ERG3_MYCBO
Sequence: MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSIATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTERIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLTKRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEPRTIDKSNAAASLVTSR
What are the official names of this protein?
C-5 sterol desaturase, Sterol-C5-desaturase.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAK_LIGS1
Sequence: MSKIIGIDLGTTNSAVAVLEGKDPKIITNPEGNRTTPSVVSFKNGETQVGEVAKRQAITNPNTVSSIKRHMGDANYKVKIEDKEYTPQEISAMILQYIKDYAESYLGEEVSQAVITVPAYFNDSQRQATKDAGKIAGLKVERIVNEPTAAALAYGLDKLDKDERILVFDLGGGTFDVSILELGDGVFEVLSTNGDTHLGGDDFDNKIIDWLVENFKADNGIDLSQDKMAMQRLKDAAEKAKKDLSGTTEAQISLPFIAAGEAGPLHLETSLSRAKFNELTEDLVERTKIPVRNALADAGLTNADIDEVILVGGSTRIPAVKEAVKAETGHTPNESVNPDEAVALGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPVAPRGVPQIEVKFDIDKNGIVNVSAKDLGTNKEQKITIKSSSGLSDEEIDRMVKEAKENEAADKKRKEEVDLRNEVDQLLFQTDKTLKEVKDKVSADEVKSVEDARDALKKAQEQSDINEMKAKKDELTKLIQDMSVKLYQQAQQAQQASGAQGDTSANNSTNDDNTVDGDFKEVDPDENK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HPRK_STAHJ
Sequence: MLTTEKLVKLLKLELFTGEKGLHKPIKNTDISRPGLEMAGYFSHYAADRIQLLGTTELSFYNLLPDEERHGRMRKLCRPETPAIIVTRGLEPPQELIDAAQEMDTPLIVSKDATTSLMSRLTTFLEHELAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIREITKDELIGTPPKLIEHLLEIRGLGIINVMTLFGAGSILTQKQIRLNINLENWDKDKLYDRVGLNEETLQILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFNQRLNEEILKKGHQSKEN
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: ISPG_MALP2
Sequence: MYKTIREKTKAVYVGNVQIGGNNKVVIQSMTTTKTHDVEKTVAQVKELVREGCELVRIAVLDDEDAAAFGEVVKNSPCPIIADIHFNPLYAIKAIESGAAKVRLNPGNIKDEEQLRKIIDLANKKNIPIRVGVNSGSLPMDLMKSHGVTADAMMIAVKRYINLFESNGFNNIVVSLKATNVLLAIEAYKKAAMEFNYPLHIGITEAGSLFNGTIKSAAGLGVLLHEGIGNTIRISLTGDPLSEVKVCKKLLNSLGLYDNLVDIISCPTCGRLNFDLNPVVKEIEKFTRKMNFPLKVAILGCAVNGPGEAKEADIGIAGGNGTGIIFANGKAIKSVPEDQLVDELKKLISIKYKEYLDSKKDK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: HFQ_SHESW
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPARPFNVTGHQNAQGGYGPQDDVPSGE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.