PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_XANCB
Sequence: MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLDEAGLRIDELDGVAYTAGPGLVGALLVGAGVARALAWALEVPAIGVHHMEGHLLAPLMEDDPPQPPFVALLVSGGHTQLVSVKALGAYEVLGETLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRGSDQSDTTRADIARGFEDAVVETLAIKCLRALDTADCNTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLEAGEHADAAVQVTPRWDMASLPPLAAARESGIGNRES
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_SALAR
Sequence: MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RL34_HISS2
Sequence: MKRTFQPSVLKRNRTHGFRARMATKNGRQVLARRRAKGRKSLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: HEMA_I56A3
Sequence: MNTQILILATSAFFYVRADKICLGHHAVSNGTKVDTLTEKGIEVVNATETVEQTNIPKICSKGKQTVDLGQCGLLGTVIGPPQCDQFLEFSANLIVERREGNDICYPGKFDNEETLRKILRKSGGIKKENMGFTYTGVRTNGETSACRRSRSSFYAEMKWLLSSTDNGTFPQMTKSYKNTKKVPALIIWGIHHSGSTTEQTRLYGSGNKLITVWSSKYQQSFVPNPGPRPQMNGQSGRIDFHWLMLDPNDTVTFSFNGAFIAPDRASFLRGKSLGIQSDAQLDNNCEGECYHIGGTIISNLPFQNINSRAIGKCPRYVKQKSLMLATGMKNVPEAPAHKQLTHHMRKKRGLFGAIAGFIENGWEGLIDGWYGYKHQNAQGEGTAADYKSTQSAINQITGKLNRLIEKTNQQFELIDNEFNEIEKQIGNVINWTRDSIIEVWSYNAEFLVAVENQHTIDLTDSEMNKLYEKVRRQLRENAEEDGNGCFEIFHQCDNDCMASIRNNTYDHKKYRKEAIQNRIQIDAVKLSSGYKDIILWFSFGASCFLFLAIAMGLVFICIKNGNMRCTICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: COAD_STRPS
Sequence: MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKAVKHLGNVKVVSSHDELVVDVAKRLGATCLVRGLRNASDLQYEASFDYYNHQLSPDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEKKD
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRI_AERS4
Sequence: MSEKNQLQVEAIRHGSVIDHVPAGQGIKILKLFQLIETQERITVGFNLKSGALGKKDLIKIENTRLTAEQANQLALFAPKATVNIIEDFAVVKKHQLELPEFITGVFHCPNSNCISHNEPVDSYFRVREVKGVVRMKCKYCEKSFTQDIVSERY
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: BOB2_ARATH
Sequence: MAIISEMEEARPSMVPFTASFDPSNPIAFLEKVLDVIGKESNFLKKDTAEKEIVAAVMAAKQRLREAEKKKLEKESVKSMEVEKPKKDSLKPTELEKPKEESLMATDPMEIEKPKEEKESGPIVPNKGNGLDFEKYSWGQNLQEVTINIPMPEGTKSRSVTCEIKKNRLKVGLKGQDLIVDGEFFNSVKPDDCFWNIEDQKMISVLLTKQDQMEWWKYCVKGEPEIDTQKVEPETSKLGDLDPETRASVEKMMFDQRQKQMGLPRSDEIEKKDMLKKFMAQNPGMDFSNAKFN
What is the function of this protein?
Small heat shock protein required for the establishment of auxin gradients and for patterning of the apical domain of the embryo.  Involved in the specification of the cotyledon primordia.  Also required for normal inflorescence and floral meristem function, normal developmental patterning and thermotolerance.  Acts as a molecular chaperone (By similarity).
What are the official names of this protein?
Protein BOBBER 2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic granule.
Protein: CD047_DANRE
Sequence: MPPDGKSDMERIGVFKEMGYISIGDKYTSFIYRPFNDSAYKNKQMLLGGTKSKCGLQTGYFDTQFKRIFEREAFTDPVRIDRQYRILQAKKNIGKAFLPSNGEKTTCGMGTYYGTFGGPIQAMSALQIPRKQNKSAGKNFYTNPPKEGSGYGCPDITLSKMVSYSSDPYDRAKEMLKREITAHKSMLKGGAFRLNLHPNEYFDGNPYKFDKPLPPPKKIEEKKHFAVPFKPSSPSKKAGGMKAGAFDSYPTYSAEPYGTKKTKSVVANNEVKIFHPSPGPKSTPIKSIISLNVNKAVNSTNYNRIPSVMSF
What are the official names of this protein?
UPF0602 protein C4orf47 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0602 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: CHLB_SYNS3
Sequence: MQLTLWTYEGPPHVGAMRIAASMKGVHYVLHAPQGDTYADLLFTMIERRDQRPPVTYTTFQARDLGGDTAELVKRHVREAVDRFQPDALLVGESCTAELIQDQPGALAAGMGLTMPIVNLELPAYSKKENWGAAETFYQLVRTLLKDQAPAELNHDPKAWQHEGRRPRVNLLGPSLLGFRCRDDVLEIQRLLNMHGIDVGVVAPLGATVADVHRLPEADLNVCLYPEIAESSCAWLERSFGIPFTTTVPIGIGATHDFLVEVHNLLGMTPPSPQEGIRQSRLPWYSESVDSTYLTGKRVFIFGDGTHALAAARICKEELGFEVVGLGTYSREMARPVRAAAKAMGIEALISDDYLAVEAAMAAAAPELVLGTQMERHSAKRLGLPCAVISTPMHVQDVPARNSPQMGWEGANVIFDSWVHPLMMGLEEHLIGMFRHDFEFVDGHQSHLGHSGGSGAIADTEVAVSTLTDELVWTAEGEAELKKIPFFVRGKVRRNTEAFAKSTGRNQIDSETLYDAKAHFSA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: AROA_SALRD
Sequence: MVQTIDQAASLRGTVSLPADKSISHRSALLSALGTGRSRVYNFPDSADPQSTLDCVRTLGIEAGRNDEGVLAIHGRGLGGLHPPSEPLDCGNSGTTMRLLSGMMAGQEFGSVLTGDESLQQRPMERIADPLQAMGARIDLRSGHAPIRIRPQRSDGLRPLEYRLPVASAQVKSCVLLAGLYASGRTVVIETTPSRDHTERMLGLEVQEVGGERHIIVEEDHTVPAVDWSVPGDFSGAAFFLVAGTLVPDSELHLDDVGLNPSRTALLDVLDGMGADITVENERVQGSEPVGDITVRSASLSGIDIGGRLIPNLIDEIPVIAVAAACAEGRTEIRDAEELRVKETDRLHAMAQNLEALGAKVQEREDGLIIDGNGPNLLGAAVTSHDDHRIAMAMGVAGLVAHGTTTISDAECARVSFPGFWDELSRVSVS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HADB_RALPI
Sequence: MTATISLATLFGEARSQNGWLDRDVPDARLREIYDQMKFGPTSVNCSPARIVFVRSMEAKQKLAGAVAPANVDKVMNAPVVAIVGYDTRFYDRLPELFPHNPAVKSWFEGPEKAAFAETTAFRNGTLQGAYLIMAARAVGLDCGPMSGFNNAAVDAAFFAGTTIRSNFICGLGHGDPGRVFPRSPRLAFEQACTLA
What are the official names of this protein?
Putative NADH dehydrogenase/NAD(P)H nitroreductase HadB.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: TRIA1_HUMAN
Sequence: MNSVGEACTDMKREYDQCFNRWFAEKFLKGDSSGDPCTDLFKRYQQCVQKAIKEKEIPIEGLEFMGHGKEKPENSS
What is the function of this protein?
Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes.  In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759).  Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602).  Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003).
What are the official names of this protein?
TP53-regulated inhibitor of apoptosis 1, Protein 15E1.1, WF-1, p53-inducible cell-survival factor, p53CSV.
What is the protein family that this protein belongs to?
Belongs to the TRIAP1/MDM35 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion intermembrane space.
Protein: FBP_PYRFU
Sequence: MKLKFWREVAIDIISDFETTIMPFFGNPDGGKLVKISPSGDETKLVDKLAEDLILSRITELGVNVVSEEVGVIDNESEYTVIVDPLDGSYNFIAGIPFFALSLAVFKKDKPIYAIIYEPMTERFFEGIPGEGAFLNGKRIKVRKTPDEKPSISFYSRGKGHEIVKHVKRTRTLGAIALELAYLAMGALDGVVDVRKYVRPTDIAAGTIIAKEAGALIKDSAGKDIDISFNATDRLDVIAVNSEELLKTILSLLE
What is the function of this protein?
Catalyzes the conversion of D-fructose 1,6-bisphosphate to D-fructose 6-phosphate.  In vitro, has also weak activity with inositol-1-phosphate, glucose-1-phosphate and glycerol-2-phosphate.
What are the official names of this protein?
Fructose-1,6-bisphosphatase, FBPase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily. FBPase class 4 family.
Protein: PESC_CAEBR
Sequence: MKDRFKQKYTAGAAVAYMSRKQALKKLQLTLKDFRRLCIIKGIYPHEPAHKKQANKGSTANKVFYYRKDINFLAHEPIINKFRDYKVFLRKLNHLKAKKEDEKIKKLYDNKPVYNLDTIVKERFPTFGSALRDMDDALSLCFTFAMLPHTRVLKEGMIDSCRKLTAEFMHYVIESQSLRNTFISIKGIYYQAEVHGEKITWVVPHERGLPHVTDVDFTVLVTFVEFYIAMLGFVNFKLYQDIGLFYPPQIGQVVEGDEMESEEYKEKVYSLAKPLAKRKDVEQTEDDEPLDLLGEDSDALAQKVKEAKNIKTLFKGCVFYLNRECPKEALTFIIRNGGGVVGWEGAPNDLKADSKNITHHIVDRPMDKLEVNRLYVQPQWVFDCLNARRKLPTERYMPGVALPPHFSPFTSEKAGDYIPFERLEELRSMGKDVSELEAAIPKTMDELPMRRKEVKPEKPKGIHIAVGQMHKKSKEKFHETVEKGQELKMRELMISKKHQRVYHSMKTTFKRNRNDALKLKKKAKLVKATAEA
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Pescadillo homolog, Lipid depleted protein 7.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: IBD2_KLULA
Sequence: MGNGNASIEFVSENGPIDFSVMMQEGVKALTKILSTHLQDNPDLINEKSMKVIFKDNNGKLEPVFAPSEGNSGLINGNDQDENYDEDRDIEEANEDYEVIEFDNEGNYHVCAKGTQNRAIGYDEKVYSKSEHYADSTDTHDYDEDGIINEDNNQLLPKDKWNGHMTRLKNGAISSAEHEVVFEHDNGDNTTFSPAETINDGHMDKRDRSHMHHSGHSEKTGGSCACQENKDSFKYPDHVPNSAPNFRALLQHTVNGKQMCPFCEYYVVFGTPPAYIMRWASSKISAEHSQYKMNDQIVDGDSGDMDRNLDSVETNEMNKQQTKKKKKKSKRKSKR
What is the function of this protein?
Part of a checkpoint which monitors spindle integrity and prevents premature exit from mitosis.
What are the official names of this protein?
Protein IBD2.
What is the protein family that this protein belongs to?
Belongs to the IBD2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle pole.
Protein: TBA_GIBZE
Sequence: MREVISINVGQAGCQIANSCWELYCLEHGIQPDGYLTEERKAQDPDQGFSTFFSETGNGKHVPRAIYCDLEPNVVDEVRTGAYRNLFHPEMMITGKEDASNNYARGHYTVGKELIDGVLDKIRRVADNCAGLQGFLVFHSFGGGTGSGFGALLMERLSVDYGKKSKLEFCVYPAPQTATSVVEPYNSILTTHTTLEHSDCSFMVDNEAIYDICRRNLGLERPNYENLNRLIAQVVSSITASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVAYSPVISAAKAAHEANSVQEMTMSCFEPNNQMVKCDPRHGKYMATCLLYRGDVVPNDAHAAVATLKTKRTIQFVDWCPTGFKLGICYQAPENVPNGDLAKVSRAVCMLSNTTAIAEAWSSLSLKFDLMHSKRAFVHWYVGEGMEEGEFSEAREDLAALERDYEEVATDSMGDEELEAEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain, Alpha-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y1117_AERPE
Sequence: MARLTYLGHAAFQLEAGGRKILVDPWLSNPKSPVKPEEVEGVDLIVITHSHFDHLGDVGKIAAKNPGAKVLAVYEVADLAAEEIAKETGASKDELFNAGRVIGANIGGPVVLQDLGLKVAFTPATHSSVGVAAGAVIITGEGRVYHAGDTGVTMDMRLVGEIYKPHVALLPIGGHFTMDPVEAAKAVELIRPLVAIPMHYGTFPVLYGDPEEFKKRVEEKCLPTQVRILKPGESYEFDFSKA
What are the official names of this protein?
UPF0173 metal-dependent hydrolase APE_1117.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: O13C6_HUMAN
Sequence: MVSANQTASVTEFILLGLSAHPKLEKTFFVLILLMYLVILLGNGVLILMTVSNSHLHMPMYFFLGNLSFLDICYTTSSVPLILDSFLTPRKTISFSACAVQMFLSFAMGATECVLLSMMAFDRYVAICNPLRYPVVMSKAAYMPIRLPAPG
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Putative olfactory receptor 13C6, Olfactory receptor, family 13, subfamily C, member 6 pseudogene, Olfactory receptor, family 13, subfamily C, member 7 pseudogene, Putative olfactory receptor 13C7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RF1_RALSO
Sequence: MKPSMLSKLDQLAERTVEINALLAREDATANLDQYRKLTREHAELEPVVAQYAAWKQAEDDVTTAQELLADPDMKAFAEDEIRAARERMTTLEAELQRLLLPKDPNDHRNIFLEIRAGTGGDESALFAGDLLRMYTRYAERQRWQVEIVSESASDLGGYKEVIVRLVGEGAYSRLKFESGGHRVQRVPATEAQGRIHTSACTVAVMPEADPLADIQINPADLRIDTFRASGAGGQHINKTDSAVRLTHLPTGLVVECQDDRSQHRNKDRAMQVLAARLKDRQEREAQAKEASARKSLIGSGDRSDRIRTYNFPQGRITDHRINLTLYKIDALMDGDLGELLGALAAEHQAEQLAALGEEA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATD_SERP5
Sequence: MFDIGVNLTSSQFAKDRPAVVERARAAGVTGLLITGTDLQESRAASELAQQHANFCWSTAGVHPHHASSWDERVAEQICELAARPRVAAIGECGLDFNRNFSTPEQQEAAFSAQLALAAELSMPVFLHCRDAHARFAALLAPWLDKLPAAVVHCFTGTAEELESCLSLGLSVGITGWVCDERRGLELRALLPQIPADRLLLETDAPYLLPRDLLPKPTSRRNEPCFLPHIVRQVAAWRQEDPEWLGQKIDENARRLFRLE
What is the function of this protein?
3'-5' exonuclease that prefers single-stranded DNA and RNA.  May play a role in the H(2)O(2)-induced DNA damage repair.
What are the official names of this protein?
3'-5' ssDNA/RNA exonuclease TatD, DNase TatD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_TOMK2
Sequence: MSYPITSPSQFVFLSSVWADPIELLNVCTNSLGNQFQTQQARTTVQKQFSEVWKPFPQSTVRFPGDVYKVYRYNAVLDPLITALLGTFDTRNSIIEVENRQSPTTAETLDATRRVDDATVAIRSAINNLVNELVRGTGLYNQNTFESMSGLVWTSAPAS
What is the function of this protein?
Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: TYPH_SHESM
Sequence: MFLAQEIIRKKRNGLALSAEEIQFFVKGITTNAVSEGQIAALGMAVYFNDMNMDERIALTTAMRDSGTVLNWQSLGLNGPVIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAIPGYQTEPSSELFRKVVKDVGVAIIGQTGDLVPADKRFYSIRDNTATVESISLITASILSKKLACSLDALAMDVKVGSGAFMPTYEASEELARSIAAVANGAGTKTTALLTDMNQVLASCAGNAVEVKEAIDFLTGAYRNPRLYAVTMGLCAEMLLLGGLATDEADARAKLNRVLDNGRAAEIFGKMVSGLGGPVDFVENYSKYLPQSQIIRPVFADTQGYAHSMDTRELGLAVVTLGGGRRKPGDALDYSVGLTQVCALGDKIDASTPIAVIHAQSEDAFAQAEEAVKKAIRIDEVAPEKTPEIYAYIRAADL
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: OSTA_MOUSE
Sequence: MEPGRTHIKLDPRYTAELLELLETNYSISPACFSHPPTAAQLLRALGPVDIALTIILTFLTTGSVAIFLEDAVYLYKNTLCPIKKRTLIWSSSAPTVVSVFCCFGLWIPRALTLVEMAITSFYAVCFYLLMMVMVEGFGGKKAVLRTLKDTPMRVHTGPCCCCCPCCPPLILTRKKLQLLLLGPFQYAFFKITLSIVGLFLIPDGIYDPGEISEKSAALWINNLLAVSTLLALWSLAILFRQAKMHLGEQNMGSKFALFQVLVILTALQPAIFSILANSGQIACSPPYSSKIRSQVMNCHMLILETFLMTVLTRMYYRRKDDKVGYEACSLPDLDSALKA
What is the function of this protein?
Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood (PubMed:15563450, PubMed:16317684, PubMed:17650074, PubMed:18292224, PubMed:22535958).  Efficiently transports the major species of bile acids (taurocholate) (PubMed:16317684, PubMed:17650074, PubMed:18292224, PubMed:22535958).  Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids (PubMed:16317684).  Can also transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, therefore playing a role in the enterohepatic circulation of sterols (By similarity).  Able to transport eicosanoids such as prostaglandin E2 (By similarity).
What are the official names of this protein?
Organic solute transporter subunit alpha, OST-alpha, Solute carrier family 51 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the OST-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Mainly restricted to the lateral and basal membranes of ileal enterocytes. Transported from the endoplasmic reticulum to the plasma membrane upon interacting with SLC51B.
Protein: MDM34_ASPFU
Sequence: MAFNFNWSPLMADASFYTRAQDLLTAALNKSPKPPIIVDDIIVTELNLGSIPPELEILEIGDLAEDRFRGIFKMSYSGDAFLTLKTRVQANPLNTYLLTRPSFATPRPLAAATPLTIPLQITLSDFKLSGFVILVFSKQKGITVVFRNDPLESLKVSSTFDSIPFVRDFLQKEIEAQLRILFMDELPAIIHRLSLRLWVPEYRAGEELQTQTASANGEGPGQDPLASPPQDPVDALGNALNESEIESLSLDSSVETHSLFSQKNLLRLAALTDSQRTLSLFTPSIREVVYRAWTSPSDQTDASGSVTSPFFPVLSRTQSQVGSMSSFPDSASMVSSQSRSSTPFHTFSGYGLSLGAGRHSKAHARKRKKRVVDLRRPKTTDDAPSVSDESSFTESTSAPSICSAPLPVLDEQTDDPVTPPLSPDNDLHLPAIPERHRMSISRPALRRENASEMIRDTAECKPSSNAVGQAIQEEDLSATPRAAVRAHGASVLEKGKQDPDSSAGSSRQLSSTILPFINDNPTGGVVDQALVERLAGEIARRMRDEKFMASNACGPFWDRHSQEESPPPAYGH
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: SYC_PERMH
Sequence: MSLKVYNTLTGKKEEFVPIKPGEVKIYTCGVTVYDVNHVGHGRSLIVFDVIRRYLRYLGYNVYFVRNFTDVDDKIINRAKNECLPFTVIADRYIKEYFQDAENFRIEPADVEPRVTTHIPDIIDFIQRLIDKGYAYEVEGDVYFSVRKFKEYGKLSKRSVDELIAGARVEPGEKKRDPLDFALWKASKAGEPAWDSPWGKGRPGWHTECCAMIFKHLGETIDIHGGGLDLTFPHHENELAQAEALSDKPFARYWIHNGLVTVNGQKMSKSLGNYITLKEIYSKYDPDVLRLLVLSVHYRSPLDFSWEKMEETKKAYERLKGAIDEYEILKKLPENPDFDEHLYDEIAKAEQGFYAAMSDDFNTPEALASLFTLVREMNILRDKAVKSGGISKKALESYKEASDVLHSIGKEIFGLFDSLQPCIEVEEIKVEKAEEKIDTQLVEALIEVRNKARKEKQFEIADYIREKLSQLGIVIEDTPVGTKWKKK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_BRUA4
Sequence: MAQAFQFELVSPERLLLSAQVTEVVIPGSEGYLTALAGHSPLMTTIMPGVVSVKLADGKSDSYVVFGGFADITPQGCTVLAESATHVDDIDPADIQRRIEHARKALDDASSNEHRTKAEIFLHQLMTLQGTIMPA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS4_HAEI8
Sequence: MKQSIIIPALDLINGQVVRLHQGDYAKQTTYSDNPIKQFDNYVRQGAKQLHLVDLTGAKNPQSRQTALIGKIVEATQCKVQVGGGIRTEQDVADLLAVGANRVVIGSTAVTHRSMVKNWFIKYGAEKFVLALDVNINASGQKIVAISGWQEESGVLLETLIEDFQTVGLQQVLCTDISRDGTLTGSNIGLYQEICEKYPPIQFQSSGGIGSLADIEALKGTGVSGVIVGRALLEGKFTLSEAIKCWQNG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_XANAC
Sequence: MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGRIATAQAGGKAVLVEVNSETDFVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGETIEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIGVLVELKGGDIELARGIAMHIAAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYGQPYVLNTDQTVEQAVKAAGAEVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.