PharMolix/UniProtQA huggingface dataset:
Protein: EXO5_CANAL
Sequence: MSRFWHFKKFYFTSCYSMQRMRGKIFKNEPLVPMNVTSEHEQVQSISKEESRSLSSNDLNLSADSELQLESEPEIESEQLKNHEDVYEIIRSMVLAADTTLPRLSNNSLTGIYNHWKLNPNDDLPLYNPTKYTPYEFHSQYNQDRSYIITPRLSVTKLLVSSWCELRSFYQVYSGSVRLPSTKAMTQGTKLHSKLEAEVHPEIDTTEIEQFLISNAMSLRELQTTVPAEEETVVIDLGEVEQLAVDWAEMLIERLFSLIMGAEAREILLHGYLNLKNRSFVTNKDEIRESSSVLVSGIVDYIKLQNVTNPSDGTLFDDIHGFVDSAFDQVDNVPLVDLSQFLPEAKQILQNYDFRLTFTDVKTRSARQIPRQESVLEAAKFQTFYYRHFFHLLSRDSRFTYFSLIENAERRGHDVDKPLSILTTISLLRKHYHIFFKDFVKLANGEPIGFSPFDDSAKSIPYDFVSMFQSSDEFSLANPNHNHFLEQISAIDGIEYDSILSPLLKVWKTPPTLRYLAARASQLFNVFNENIGDITSVEYRYNKTSELLSEKVYDYNFSEFQAEVESASKFWNGEREVIPTEDLSRCSYCEFQSKCMVAGGKTTEAVEKKTIGPKIRQFLNECESSSKG
What is the function of this protein?
Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination.  Releases dinucleotides as main products of catalysis.  Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).
What are the official names of this protein?
Exonuclease V, mitochondrial, Exo V, Defects in morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the EXO5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KDSB_METPB
Sequence: MSDPLILIPARLAATRLPSKPLADIAGEPMIVHVWRRAVEAGIGPVVVATDTDAIAAAIEAQGGLAVMTQPDHPSGSDRLAEALEIVDPDGNHDVVVNVQGDLPTIDPAIIAASVTPLADPQVDIATLCAVIHRPEEMDDPNVVKIIGHTVGPNRLRALAFTRARAPWGEGPLFHHIGLYAYRRKALARFVALPQGELERREKLEQLRALEAGMRIDAMIVEDLPLGVDTPADLERARTLLAIRRLN
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOXP1_RAT
Sequence: MMQESGSEAKSNGSTIQNGSSGGNHLLECGTLRDTRSNGEAPAVDLGAADLAHVQQQQQQALQVARQLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGSNHSSLDLTSTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCDDFPAFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSGHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGSLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPIHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME
What is the function of this protein?
Transcriptional repressor.  Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential.  Plays an important role in the specification and differentiation of lung epithelium.  Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2.  Essential transcriptional regulator of B-cell development.  Involved in regulation of cardiac muscle cell proliferation.  Involved in the columnar organization of spinal motor neurons.  Promotes the formation of the lateral motor neuron column (LMC) and the preganglionic motor column (PGC) and is required for respective appropriate motor axon projections.  The segment-appropriate generation of spinal cord motor columns requires cooperation with other Hox proteins.  Can regulate PITX3 promoter activity; may promote midbrain identity in embryonic stem cell-derived dopamine neurons by regulating PITX3.  Negatively regulates the differentiation of T follicular helper cells T(FH)s.  Involved in maintenance of hair follicle stem cell quiescence; the function probably involves regulation of FGF18.  Represses transcription of various pro-apoptotic genes and cooperates with NF-kappa B-signaling in promoting B-cell expansion by inhibition of caspase-dependent apoptosis.  Binds to CSF1R promoter elements and is involved in regulation of monocyte differentiation and macrophage functions; repression of CSF1R in monocytes seems to involve NCOR2 as corepressor.  Involved in endothelial cell proliferation, tube formation and migration indicative for a role in angiogenesis; the role in neovascularization seems to implicate suppression of SEMA5B.  Can negatively regulate androgen receptor signaling (By similarity).  Acts as a transcriptional activator of the FBXL7 promoter; this activity is regulated by AURKA (By similarity).
What are the official names of this protein?
Forkhead box protein P1.
What are the subcellular locations of this protein?
Nucleus. Note=Not found in the nucleolus.
Protein: ISPG_SALSV
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPITVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNDDMIAQLESRIRAKASQLDEARRIDVLQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RL10_THESQ
Sequence: MLTRQQKELIVEEMSEIFKKTSLILFADFLGFTVADLTELRSKLREKYGDGARFRVVKNTLLNLALKNAEYEGYEEFLKGPTAVLYVTEGDPVEAVKIVYNFYKDKKADLSRLKGGFLEGKKFTAEEVENIAKLPSKEELYAMLVGRVKAPITGLVFVLSGILRNLVYVLNAIKEKKSE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: GATA_CANAW
Sequence: MRKTLTSIRFLSDGIRVKDKWNSLISDLVVEPTNSTGPLSGTTYIVKDNIATSHGYTTAASKILSNYESPFNATIIDLLSSNGSKLIGKSNLDEFGMGSANYNSYFNKVTNPYDNTKVPGGSSGGSAASVAGKMCSFSIGTDTGGSVRLPASYCNVFGFKPTYGRISRWGVIPYAQTLDTVGIIGENVNIIKRVYDVLNKYDDKDPTCLPEEVRQKIPTTKKETLTIGVPHEFVLKELSADVRESWEYALSKICKLGHLVKPISIKTIKKALPSYYTLATAEAASNLSRYDSIRYGYNTNESVNSPIELIATNRSDGFGSEVQRRILLGNYTLSSDSGDHYLRATQIREELCAEFSSIFNNSHVLLQDEQSSDKVDLIMAPTSTSTAPTWDEFVSANEKNFLNSYVNDVLTVPASLAGIPAISVPVNGIGIQLMGQFGDDDLVLQLADQI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TXH5_CYRSC
Sequence: MKSIVFVALFGLALLAVVCSASEDAHKELLKEVVRAMVVDKTDAVQAEERECRWYLGGCSQDGDCCKHLQCHSNYEWCVWDGTFSK
What is the function of this protein?
Omega-theraphotoxin-Hs2a blocks voltage-gated calcium channels (Cav) in adult cockroach DUM neurons.  Reversibly paralyzes locusts and cockroaches, and causes death at high doses,.
What are the official names of this protein?
Omega-theraphotoxin-Hs2a, Omega-TRTX-Hs2a, Huwentoxin-5, Huwentoxin-V, HwTx-V.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 17 (Hntx-9) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: STLK_DROME
Sequence: MMCSNNISDYKLLEILKNGMIGTVYKAEDINNKCLAVKKVSMDQPMEKLTLLFNEVLTVRRLQHRNINTIVSCFLYKQYVYLTYKFMCFGNCEVLLKNVYTSGFPEVAIALILKDVLSALTYIHSEHYVHGSVRAKHILLSPRKAVLSNFSYCQSFISQGEKKTFIFGSTVGIEKELYWTAPEVLYQNLSGYTEKIDIYSIGITCCEMANGFQPFKDTELTYMYIEKVRGSLQVLLDKNSLLENQGSLSLEHTNKRIARDVIVNKSFSENFHQFVELCLNKNPLSRWAASKLMTHSFLKQCRNTSLLDQLKDLGQKMSKFKRNEHEIFSDARGSHNPQPNDTIWKF
What are the official names of this protein?
Putative serine/threonine-protein kinase STE20-like.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: FRSA_YERPY
Sequence: MAQANLSEILFKPKFKHPETSTLVRRTHCNHVVNIHSALDGDTANHWYRMINRLMWTWRGIDPLEIEEVLSRIACSKAEHSNNELLDTVVGYRNGNWIYEWANQGMMWQQKAMEETDPGSAGQFWLNAANLYSIASYPHLKGDELSEQAEVLSNRAYEEAAKYLPYTLKELTFPISDGGSLSGFLHMPTVGSAPFPTVLMCGGLDTLQSDYHRLFRDYLEPKGIAMLTIDLPSVGASSRWKLTQDTSYLHQQVLQALADVPWVDHQRVSVFGFRFGANVAVRLGYLEPQRVRAVACLGPIVHHLLCNSDSLRKVPDMYMDVMASRLGMADSTDETLNTEMNRYSLKTQGLLGRRCQTPMLAGFWENDPFSPKEEAKLICSSSADGKLLAIPSKPLYENFHRALLQTSEWLEDKMR
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: TRUA_ALIF1
Sequence: MRIALCIEYDGAEYYGWQRQRDVNSVQEELEKALTIVANEPIEVHCAGRTDAGVHGTGQVVHFDTTSSRKLAAWMMGANANLPKNIAVRWAKEVNEDFHARFTATARRYRYIIYNNRLRPAILGHGVSHYHDALDANLMHEAGQYLLGENDFTSFRAVHCQSRSPWRNLMHLKVTRHGDFIVIDIKANAFVHHMVRNITGSLIEVGKGKQKPEWIKWLLEAKDRKLAGATAKAEGLYLVDVDYPLEWELPRVPLGPLFLDND
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LPXD_TOLAT
Sequence: MTITLGQLAQHLGAELHGDADVIIQRIANLETAQAGEIGFLSDSKYQQYLATTQASAVLLRAADLAMCQTNALVVKDPYIAFARVAQLLDSTPAPAVNIHPSAVIADDVQLGQGVAVGANAVIETGVVLGDGAIIGAGCFVGKNSKLGARSKLWANVTIYHNVRIGDDCLVQSGTVIGADGFGYANERGEWIKIPQLGGVVIGNRVEIGSNTCIDRGAIDDTRIADNVIIDNLCQIAHNVEIGYGTAIAGAATFAGSTKIGKYCIIGGASVFNGHIEICDQVTVTGMAMVMRSITEPGLYSSGIPAQTNKEWRKTAARTLHIDDMYKRLSNIEKLLDKQEQK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RL28_BARBK
Sequence: MSRACELTGKTVQYGNNVSHANNKTRRRFLPNLCNVTLISEVMQQSYRLRISANAVRSVEHRGGLDNFLTKADDKELSQRARLLKRQIVKKKAEQAAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DEGS_SALT1
Sequence: MFVKLLRSVAIGLIVGAILLAVMPSLRKINPIAVPQFDSTDETPASYNFAVRRAAPAVVNVYNRSMNSTAHNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINTKRTPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGLGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQQGSGMDPIQGIVVNEVTPNGPAALAGIQVNDLIISVNNKPAVSALETMDQVAEIRPGSVIPVVVMRDDKQLTFQVTVQEYPASN
What is the function of this protein?
A site-1 protease (S1P) that cleaves the peptide bond between 'Val-148' and 'Ser-149' in RseA.  When heat shock or other environmental stresses disrupt protein folding in the periplasm, DegS senses the accumulation of unassembled outer membrane porins (OMP) and then initiates RseA (anti sigma-E factor) degradation by cleaving its periplasmic domain, making it a substrate for subsequent cleavage by RseP.  This cascade ultimately leads to the sigma-E-driven expression of a variety of factors dealing with folding stress in the periplasm and OMP assembly.  Required for basal and heat shock-induced degradation of RseA but not for acid stress response in this strain.
What are the official names of this protein?
Serine endoprotease DegS, Site-1 protease DegS, S1P protease DegS, Site-1-type intramembrane protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FEOC_ECO45
Sequence: MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLKQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLHEWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: SYP_VEREI
Sequence: MKASRFFVSTLKDAPADAEVVSHQLMMRAGLIKKLGAGIYSYMPMGLRVLRKIEAIVREEMNRAGAVELTMPVVQPAELWQETGRFDKMGPELLRIQDRHGRDFVVQPTSEEVITDIARQELRSYKQLPKNFYQIQTKFRDERRPRFGLMRGREFIMKDAYSFDRDPAAAKASYLVMEQAYRRIFDRFGLTYRAVAADSGAIGGDLSEEFQVVAATGEDAIVYCPQSDYAANMEKAEALAPSGVRGAATRALNKTSTPDKSTCAEVAQWLGVPLQSTVKSLVMATDEAQAADGSVKSQVWLLLLRGDHDMNQVKVAKLPGLGQGLRFATLDEIEAHFGCQPGYLGPIGLQKPLKIVADRDVALMADWICGANEAHWHLTGVNWGRDLPEPDMVADLRNVVAGDRSPDGKGVLAIERGIEVGHVFYLGTKYSRAMNASFLDENGKPQPLEMGCYGIGITRLPAAAIEQNHDARGIIWPDAIAPFTAVICPIGMERSAAVQAAADKLYADFLAAGIDVLLDDRGERPGAMFADWELIGVPHRVVISERGLKEDQLEYQHRRDQSATKVAAADILAHVKGRMTV
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_STRU0
Sequence: MGKCQVISHPLIQHKLSILRREDTSTKNFRELVNEIAMLMGYEVSRDLPLEDVEIQTPVAKTIQKQLTGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGMYRDEETLEPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGAGNIKFVCLVAAPEGVKKLQEAHPDVDIYTAALDEKLNEHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: BGAL_STRTR
Sequence: MNMTEKIQTYLNDPKIVSVNTVDAHSDHKYFESLEEFSEGEMKLRQSLNGKWKIHYAQNTNQVLKDFYKTEFDETDLNFINVPGHLELQGFGSPQYVNTQYPWDGKEFLRPPQVPQESNAVASYVKHFTLNDALKDKKVFISFQGVATSIFVWVNGNFVGYSEDSFTPSEFEISDYLVEGDNKLAVAVYRYSTASWLEDQDFWRLYGIFRDVYLYAIPKVHVQDLFVKGDYDYQTKAGQLDIDLKTVGDYEDKKIKYVLSDYEGIVTEGDASVNGDGELSVSLENLKIKPWSAESPKLYDLILHVLDDDQVVEVVPVKVGFRRFEIKDKLMLLNGKRIVFKGVNRHEFNARTGRCITEEDMLWDIKVMKQHNINAVRTSHYPNQTRWYELCDEYGLYVIDEANLETHGTWQKLGLCEPSWNIPASEPEWLPACLDRANNMFQRDKNHASVIIWSCGNESYAGKDIADMADYFRSVDNTRPVHYEGVAWCREFDYITDIESRMYAKPADIEEYLTTGKLVDLSSVSDKHFASGNLTNKPQKPYISCEYMHTMGNSGGGLQLYTDLEKYPEYQGGFIWDFIDQAIYKTLPNGSEFLSYGGDWHDRPSDYEFCGNGIVFADRTLTPKLQTVKHLYSNIKIAVDEKSVTIKNDNLFEDLSAYTFLARVYEDGRKVSESEYHFDVKPGEEATFPVNFVVEASNSEQIYEVACVLREATEWAPKGHEIVRGQYVVEKISTETPVKAPLNVVEGDFNIGIQGQNFSILLSRAQNTLVSAKYNGVEFIEKGPKLSFTRAYTDNDRGAGYPFEMAGWKVAGNYSKVTDTQIQIEDDSVKVTYVHELPGLSDVEVKVTYQVDYKGRIFVTANYDGKAGLPNFPEFGLEFAIGSQFTNLSYYGYGAEESYRDKLPGAYLGRYETSVEKTFAPYLMPQESGNHYGTREFTVSDDNHNGLKFTALNKAFEFSALRNSTEQIENARHQYELQESDATWIKVLAAQMGVGGDDTWGAPVHDEFLLSSADSYQLSFMIEPLN
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: PSMA1_STAA8
Sequence: MGIIAGIIKVIKSLIEQFTGK
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 1 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: CRYAA_MACMU
Sequence: MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKIQTGLDATHERAIPVAREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: HBA_CHRRI
Sequence: VLSGSDKTNVKGVFGKIGGHAEEYGAETLERMFATYPQTKTYFPHFDLQHGSAQVKAHGKKVAAALVEAANHIDDIAGALSKLSDLHAQKLRVDPVNFKLLGQCFLVVVAIHHPSVLTPEVHASLDKFLCAVGNVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ATPA_CERS4
Sequence: MGIQAAEISAILKEQIKNFGQQAEVAEVGRVLSVGDGIARVHGLDNVQAGEMVEFPGGIRGMALNLEVDNVGVVIFGDDRSIKEGDTVKRTKSIVDVPAGDALLGRVVDGLGNPIDGKGPIAATERRVADVKAPGIIPRKGVHEPMATGLKSVDAMIPIGRGQRELIIGDRQTGKTAIALDTILNQKSYNEAAGDDESKKLYCIYVAIGQKRSTVAQLVKKLEETGAIDYTLVVAATASDPAPMQFLAPYAATAMAEYFRDNGRHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSAKLNKDHGAGSLTALPIIETQGGDVSAFIPTNVISITDGQIFLETELFYQGIRPAVNTGLSVSRVGSSAQTDAMKSVAGPVKLELAQYREMAAFAQFGSDLDAATQQLLNRGARLTELMKQPQYAPLTNAEIVCVIFAGTKGYLDKVPVKDVGRWEQGLLKHLRTNAKDLLADITNNDRKVKGELEDKIRAALDTYAKDFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS4_DICNV
Sequence: MARYIGPKCRLARREGVDLELKSGVRPSESKCNMNAAPGQHGGRRGRLSDYGGQLREKQKLKRTYGVLERQFRNYYKKAVQQKGSTGENLLILLEQRLDNVVYRMGYGSTRAEARQLVSHGAIEVNGQRVTIASYQVQAEDIVSVREQSRKQIRIQSALEIAKQRGFVDWIEVDAAKMSGQFKRVPERIDLSADINESLVVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TX14A_TETBN
Sequence: MKIIKLITIFTMMATLMXXVANGEPIPPNAVKSLQG
What are the official names of this protein?
U14-myrmicitoxin-Tb1a, U14-MYRTX-Tb1a.
What are the subcellular locations of this protein?
Secreted.
Protein: TIM13_USTMA
Sequence: MDLSSLTGKSAAAGGATSAERKEAIKQQVSSELAMANAQQLITKATEKCYSKCIPAPGASLSGKEQTCLTRCMERYFEAFNIVSSTYVRRVSNERAAGAVAEAGL
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM13.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: TIM16_DICDI
Sequence: MAARLIAKIVFTSGTVLVRSIQMAYKQALLQAESGMGAAAGSMDVKSKMSPIEARKILGLENVETVSKEDIDKKYNELLTINDPKDGGSEYLQIKISGAKHCLHSALKEGKKI
What is the function of this protein?
Regulates ATP-dependent protein translocation into the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim16, Presequence translocated-associated motor subunit pam16.
What is the protein family that this protein belongs to?
Belongs to the TIM16/PAM16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: COGA1_HUMAN
Sequence: MWVSWAPGLWLLGLWATFGHGANTGAQCPPSQQEGLKLEHSSSLPANVTGFNLIHRLSLMKTSAIKKIRNPKGPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQVTDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEILPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG
What is the function of this protein?
Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology.
What are the official names of this protein?
Collagen alpha-1(XVI) chain.
What is the protein family that this protein belongs to?
Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.