PharMolix/UniProtQA huggingface dataset:
Protein: THIG_EXIS2
Sequence: MLEIGGKTFASRLLLGTGKYPDATTQQQAVEASGTNILTFSVRRLDVFAKGQTNPLAALDLNRYDLLPNTAGAKTAEEAVRLARLARASGMCDMVKVEVIGCDKTLLPDPVETLRASEELIKDGFIVLPYTSDDLLLARRLEELGCHAIMPAASPIGSGQGILNPLALSFIIEQLTVPVIVDAGIGSPADVAYAMELGADAVLLNSAVAHSGDPVKMAQAMKLAVEAGRLGFEAGRIEKKRYATASSPMTGISRP
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAO2_BACSU
Sequence: MGYYLTWLTISRKKEICLNNIKKTKEGHLETTLRGKEVLSIPTLNKGVAFSLEERQELGLEGLLPPTVLSLDQQAQRAYEQFQAQPDRLRQNVYLSDLANRNEVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYLSIDNIDGIEKAFENLHATAGDIDLIVATDSESILGIGDWGVGGINIAIGKLAVYTAAAGIDPSRVIPVVLDVGTNNEKLLNDPLYIGNKHERVQGERYEAFIDAYVKAALKFFPKALLHWEDLGNKNARNIMKKYNHEILTFNDDIQGTGAITLAGVLAAMKKTGASIKDQRVVIFGAGSAGIGIADQIRDTMVLAGLSEEEANKRFYTLDYRGLLTEDIEGILDFQKPYLRNADEVKDWKRDEKGQIPFDEVVRQAKPTILIGTSGVSGAFTEEIVKEMASHVDRPVIMPMSNPTHLAEAVPEDLFKWTDGKVLIATGSPFDNVEYNGVSYEIGQSNNAFAFPGLGLGSIVAEARIITPAMFAATADAIAEMVDLETPGAGLLPSIDKLQEVSIQVAIAVAEAAIKDGVANRQPEDVKQAVLDAMWTPEYKKVIAK
What is the function of this protein?
Catalyzes the decarboxylation of malate to pyruvate (PubMed:12949160, PubMed:16788182).  Can use NAD and NADP, but with a strong preference for NAD (PubMed:12949160, PubMed:16788182).  Can also catalyze the decarboxylation of oxaloacetate (PubMed:16788182).  Involved in keeping the ATP levels high (PubMed:23136871).
What are the official names of this protein?
NAD-dependent malic enzyme 2, NAD-ME 2, Malate dehydrogenase MaeA, Malic enzyme A.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: INT9_MACFA
Sequence: MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSSLPGWSLKDGNAFLDKTELIDLSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTVQIGRLLMEELVNFIERVPKAQSASLWKNKDIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGFSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLVLTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSSVPLYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFRQPCVVFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHLLQPPPRPAQPTSGKKRKRVSDDVPDCKVLKPLLSGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEMLRVRLRDLVLKFLQKF
What is the function of this protein?
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
What are the official names of this protein?
Integrator complex subunit 9, Int9.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOC_THEP3
Sequence: MFQLRNFEAIKIGLASPEKIREWSRGEVKKPETINYRTLKPERDGLFCERIFGPTKDWECHCGKYKRVRYKGVVCDRCGVEVTRSKVRRERMGHIELAAPVAHIWYVKGIPSRMGLLLDMSPRALEKVLYFVSYVVIDPGDTPLTKKQLLSEKEYRDYLDKYGNRFRAGMGAEAIKELLQEIDLEKLSKELRAEIRESTGQKRVRAIRRLEVVQAFIDSGNRPEWMILDVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKKLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKVYQCGLPKEMALELFKPFVMKKLVDEGLAQHIKSAKRMVEKVKPEVWDVLEEVIKEHPVLLNRAPTLHRLGIQAFEPVLVEGRAIKLHPLVCTAYNADFDGDQMAVHVPLSMEAQAEARFLMLAANNILKPQDGKPVMTPTQDMVLGCYYLTADEEGVPGEGKYFSSPEEAIMAYQLGYIHIHAKIKVKMTKEIDGVKKSKIIETTVGKIIFNEAIPQDLGYVDRTNPETAFDLEINDLVDKSKLGKILDRVYRLHGPTKTAETLDKIKELGFRYSTKAAITVSVSDMVIPKEKEKLLKEADEMVSKIESQFRRGLISEEERYESVIRTWNMTTEKVTEALMASLDKFNPIFMMAHSGARGSKNQIRQLAGMRGLMADPSGRIIELPIRSNFREGLNVLEFFISTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREDDCGADEGIYVEEIREGNEIIEKLADRIIGRVAAEDVIDNEGNIIVRRNELINEEEAEKIEKAGITKVRIRSLLTCKSRHGVCRMCYGRDLATGELVNIGEAVGIIAAQAIGEPGTQLTMRTFHTGGVAGADITQGLPRVEELFEARKPKGLAVISEISGVVRINESKKRREVIVTDEENNISKTYLIPYGSRLKVHDGQVIQAGDELTEGSVNPHDLLKIKGIFAVQTYLLQEVQKVYRLQGVEINDKHIEVIIRQMMRKVKVEDPGDTSMLPGELIDMFKFEDENKKAIEKGLRPATGRRALLGITKAALATDSFLSAASFQETTRVLTDAAIKGKVDPLLGLKENVIIGKLIPAGTGLSRYRNISVVKKVNDQQERQDKEKEETEVKASN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SYS_PROM1
Sequence: MIDQRLLRENPNLISEGLKSRGMDVDLGPLQKFCKDLKDLEEKRNSLQAQGNSIGKEVGQKIKQGLPHDSEEISNLRVKGNQIKKQVGIIEEEEKSISNKLNEQILCLPNLPEKNSLEGKNEKDNKELRRWGEPISGNTLKEHWEIANQLNLWDSERSSVIAKSRFVTLFKHAAKLERSLINFMLDLHIKKGYLEVLPPALVNTASLTGSGQLPKFAEESFRCADDDLWLTPTAEVPITSLHRGEIIPRDLLPLKYVAYSPCFRREAGSYGRDTRGLIRLHQFNKVELYWFSTPETSEDALEQITSDAESVLQELELPYRVIQLCTGDLGFSAKKTYDLEVWLPGANTFREISSCSNCGDFQARRSSIRTKDNNKKNILLHTLNGSGLAIGRTMAAILENGQQSDGSINLPKALIPYFGSNKLQPE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_STRPN
Sequence: MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATL1_FELCA
Sequence: MHPLLFLAGLCLGVASAAPQLYQSLDARWSQWKATHGKLYGMDEVWRRAVWERNMKMIEQHNREHSQGKHTFTMAMNAFGDMTNEEFRQVMNGLKIQKRKKWKVFQAPFFVEIPSSVDWREKGYVTPVKDQGYCLCCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSQTEGNEGYSGGLIDDAFQYVKDNGGLDSEESYPYHAQGDSCKYRPENSVANVTDYWDIPSKENELMITLAAVGPISAAIDASLDTFRFYKEGIYYDPSCSSEDVDHGVLVVGYGADGTETENKKYWIIKNSWGTDWGMDGYIKMAKDRDNHCGIASLASFPTV
What is the function of this protein?
Thiol protease important for the overall degradation of proteins in lysosomes (By similarity).  Plays a critical for normal cellular functions such as general protein turnover, antigen processing and bone remodeling.  Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity).  In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin peptide neurotransmitter (By similarity).  In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound peptide ligands presented by cortical thymic epithelial cells.  Also mediates invariant chain processing in cortical thymic epithelial cells.  Major elastin-degrading enzyme at neutral pH.  Accumulates as a mature and active enzyme in the extracellular space of antigen presenting cells (APCs) to regulate degradation of the extracellular matrix in the course of inflammation (By similarity).  Secreted form generates endostatin from COL18A1 (By similarity).  Critical for cardiac morphology and function.  Plays an important role in hair follicle morphogenesis and cycling, as well as epidermal differentiation (By similarity).  Required for maximal stimulation of steroidogenesis by TIMP1 (By similarity).
What are the official names of this protein?
Procathepsin L, Cathepsin L1, Progesterone-dependent protein, PDP.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Apical cell membrane; Peripheral membrane protein; Extracellular side. Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Secreted, extracellular space. Secreted. Note=Localizes to the apical membrane of thyroid epithelial cells. Released at extracellular space by activated dendritic cells and macrophages.
Protein: DNLI_SULIY
Sequence: MEFKVIAEYFDKLEKISSRLQLTALLADLLSKSDKAIIDKVVYIIQGKLWPDFLGYPELGIGEKFLIKAISIATNTDENSVENLYKSIGDLGEVARRLKSKQQSTGILGFLGTSSKESLKVDEVYSTLSKVALTTGEGSRDLKIRLLAGLLKKADPLEAKFLVRFVEGRLRVGIGDATVLDAMAIAFGGGQSASEIVERAYNLRADLGNIAKIIVEKGIEALKTLKPEVGIPIRPMLAERLSNPEEILKKVGGSALVDYKYDGERAQIHKKDDKIFIFSRRLENITSQYPDVVEYISKYTEGKEFIIEGEIVAVDPESGEMRSFQELMHRKRKSDIYEAIKEYPVNVFLFDLMYYEDVDYTTKPLEVRRKLLESIVKPNDYVKIAHHIQVNNIEDLKSFFYRAISEGGEGVMVKAIGKDAIYQAGARGWLWIKLKRDYQSEMADTVDLVVVGGFYGKGKRGGKISSLLMAAYNPKTDTFESVCKVASGFSDEQLDELQKKLMEIKRDIKHPRVNSKMEPDIWVEPVYVAEIIGAEITISPLHTCCQDVVEKDAGLSIRFPRFIRWRDDKSPEDATTTDEILEMYNKQPKKKIESPPIDESV
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: YQIA_SHIFL
Sequence: MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYPSDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDYLGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYASCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL
What is the function of this protein?
Displays esterase activity toward palmitoyl-CoA and pNP-butyrate.
What are the official names of this protein?
Esterase YqiA.
Protein: YEAY_ECOLI
Sequence: MAVQKNVIKGILAGTFALMLSGCVTVPDAIKGSSPTPQQDLVRVMSAPQLYVGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPTLGEPSRGRIYADVNGFLDPVDFRGQLVTVVGPITGAVDGKIGNTPYKFMVMQVTGYKRWHLTQQVIMPPQPIDPWFYGGRGWPYGYGGWGWYNPGPARVQTVVTE
What are the official names of this protein?
Uncharacterized lipoprotein YeaY.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PG140_VAR67
Sequence: MDMMLMIGNYFSGVLIAGIILLILSCIFAFIDFSKSTSPTRTWKVLSIMSFILGIIITVGMLIYSMWGKHCAPHRVSGVIHTNHSDISVN
What is the function of this protein?
Envelope protein which is a major component of the mature virion (MV) membrane.  Essential for membrane biogenesis.  Is required, together with OPG144, to form bona fide crescents, which can progress to form the immature virion (IV) membrane.  OPG140 and OPG144 form a lattice that is stabilized by disulfide bonds and serves as an anchor within the viral membrane to which several other proteins important in virion structure and morphogenesis attach.
What are the official names of this protein?
Virion membrane protein OPG140.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG140 family.
Protein: ACPS_RHILO
Sequence: MIIGIGSDLIDIRRIENSLERHGQRFVQRIYTEVEQARSENRRARAASYAKRFAAKEACAKALGTGLAQGVFWRDMGVVNLPSGAPTMALTGGALARLEKILPPGHKAAIHLTITDDFPLAQAFVIIEALPVEQAPH
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MHPD_COMTE
Sequence: MPTTTQIQAWAERLRHAEATATPIAPLREEITDNDSAYAVQLVNVQYAQSQGRRIVGRKIGLTSLAVQKQLGVDQPDFGTLFADMLYGDDEAVPLSRTLQPKVEAEVALVLAKDLERPDTTLVDVISATAYVLPAIEIVGSRIADWNIRFIDTVADNASSGLVVLGAVPTALNALDLKLCQMQMTRNGDVVSTGSGGACLGHPLNAAVWLARRLANLGQPLRAGDLVLTGALGPMVAVNAGDRFEARISGIGSVCAQFEG
What is the function of this protein?
Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.
What are the official names of this protein?
2-keto-4-pentenoate hydratase, 2-hydroxypentadienoic acid hydratase.
What is the protein family that this protein belongs to?
Belongs to the hydratase/decarboxylase family. MhpD subfamily.
Protein: OL141_ARAHY
Sequence: MATATDRAPHQVQVHTPTTQRVDVPRRGYDVSGGGIKTLLPERGPSTSQIIAVLVGVPTGGTLLLLSGLSLLGTIIGLAIATPVFTFFSPVIVPAVVTIGLAVTGILTAGACGLTGLMSLSWMINFIRQVHGTTVPDQLDSVKRRMADMADYVGQKTKDAGQQIQTKAQDVKRSSS
What is the function of this protein?
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil.  Probably interacts with both lipid and phospholipid moieties of lipid bodies.  May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.
What are the official names of this protein?
Oleosin Ara h 14.0101, Oleosin 5 variant A.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface.
Protein: TBB_EPITY
Sequence: MREIVHLQTGQCGNQIGAAFWQTISGEHGLDSNGVYNGTSELQLERMSVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICMRTLKLSNPSYGDLNYLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGKVAMKEVEDQMRNVQNKNSSYFVEWIPNNIQTALCAIPPRGLKMSSTFIGNSTSIQELFKRVGEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAGIDEEEEEYEEEAPVDEPLE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CIPKH_ARATH
Sequence: MVIKGMRVGKYELGRTLGEGNSAKVKFAIDTLTGESFAIKIIEKSCITRLNVSFQIKREIRTLKVLKHPNIVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSYCHNKGVFHRDLKLENVLLDAKGHIKITDFGLSALSQHYREDGLLHTTCGSPNYVAPEVLANEGYDGAASDIWSCGVILYVILTGCLPFDDANLAVICRKIFKGDPPIPRWISLGAKTMIKRMLDPNPVTRVTIAGIKAHDWFKHDYTPSNYDDDDDVYLIQEDVFMMKEYEEEKSPDSPTIINAFQLIGMSSFLDLSGFFETEKLSERQIRFTSNSLAKDLLENIETIFTEMGFCLQKKHAKLKAIKEESTQKRQCGLSVTAEVFEISPSLNVVELRKSHGDSSLYKQLYERLLNELGSSSQVQELLA
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting serine/threonine-protein kinase 17, SNF1-related kinase 3.21, SOS2-like protein kinase PKS20.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: MDTG_ECO8A
Sequence: MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNPKLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAVYSWNSLRRRRIPQVSN
What is the function of this protein?
Confers resistance to fosfomycin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL35_ESCF3
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RIBB_SYNC1
Sequence: MSQSLLDRFGTPLERVHLAIDRLRQGRGVLLVDDENRENEGDLIFPAETITPAQMAMMIRECSGIVCLCLTEDKLKQLELPQMVSDNTSANQTAFTLSIEARQGVTTGVSAADRVTTIRTAVADDCRPDDLARPGHVFPLRARPGGVLTRRGHTEGTVDLMRMAGYKPAGVLCELTNEDGTMARLPEIITFAERHYLSVVSIEDLALALESHMEKSA
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: LEGRE_VIGUN
Sequence: MAMASLARRKAYAVVSSSRSSVFLTSLRGFASGSDENDVVVIGGGPGGYVAAIKASQLGLKTTCIEKRGTLGGTCLNVGCIPSKALLHSSHMYHEAKHSFANHGIKLSSVEVDLAGMMAQKDKAVSNLTKGIEGLFKKNKVNYVKGYGKFVSPSEVSVDTIDGGNTVVKGKHIIIATGSDVKSLPGVTIDEKKIVSSTGALALTEIPKKLVVIGAGYIGLEMGSVWGRLGSEVTVVEFASDIVPTMDAEVRKQFQRSLEKQGMKFQLKTKVVGVDTSGDGVKLTLEPAAGGDQTILETDVVLVSAGRTPFTAGLGLDKIGVETDKIRRILVNERFTTNVSGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKVGHVDYDKVPGVVYTTPEVAYVGKTEEQVKALGVEYRVGKFPFMANSRAKAIDNAEGLVKILAEKETDKILGVHIMAPNAGELIHEAAIALQYDASSEDIARVCHAHPTMSEAVKEAAMATYDKPHSHMKSWLLLHSLLFIFVQQFTMTWR
What is the function of this protein?
Reduces ferric leghemoglobin (Lb) to ferrous Lb.
What are the official names of this protein?
Leghemoglobin reductase, Ferric leghemoglobin reductase, FLbR.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CRL_PECAS
Sequence: MMLPSGHPKSRLMKNFTALGPYIREAQCEDTAFFFDCLAVCVNIKPAPEEREFWGWWLNLEDTGKAFSYEYHYGLFDKQGNWREEKIKGKAVIEQVENAKQAFHVRLEKLLRSLEPACTLVARP
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_PORGI
Sequence: MLQPKKTKFRRQQKGRMKGFAQRGNQLSFGSFGIKSLQSKWITGRQIEAARIAVTRYMQRQGQVWVRIFPDKPITKKGEGVRMGKGKGAPEGFVAPITPGRIIFEVEGVPYEIAKEALRLAAQKLPVTTKFVVRHDYDIQNQNA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PSBU_SYNP6
Sequence: MKQLAQRLFSLALVLALVLGISVQSAQALSLQSPLLAVAEAEIRNEADAQRIEAGGKLDLNNIGVRAFQQFPGMYPYLASKIVLGGPYDSVDDVLKLDLSDRQREVFEQYKENFTVTPPRDALNEGDDRINNGIYR
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: ZKSC3_HUMAN
Sequence: MARELSESTALDAQSTEDQMELLVIKVEEEEAGFPSSPDLGSEGSRERFRGFRYPEAAGPREALSRLRELCRQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHPESGEEVVVLLEYLERQLDEPAPQVSGVDQGQELLCCKMALLTPAPGSQSSQFQLMKALLKHESVGSQPLQDRVLQVPVLAHGGCCREDKVVASRLTPESQGLLKVEDVALTLTPEWTQQDSSQGNLCRDEKQENHGSLVSLGDEKQTKSRDLPPAEELPEKEHGKISCHLREDIAQIPTCAEAGEQEGRLQRKQKNATGGRRHICHECGKSFAQSSGLSKHRRIHTGEKPYECEECGKAFIGSSALVIHQRVHTGEKPYECEECGKAFSHSSDLIKHQRTHTGEKPYECDDCGKTFSQSCSLLEHHRIHTGEKPYQCSMCGKAFRRSSHLLRHQRIHTGDKNVQEPEQGEAWKSRMESQLENVETPMSYKCNECERSFTQNTGLIEHQKIHTGEKPYQCNACGKGFTRISYLVQHQRSHVGKNILSQ
What is the function of this protein?
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy.  Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2.  Associates with chromatin at the ITGB4 and VEGF promoters.  Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.
What are the official names of this protein?
Zinc finger protein with KRAB and SCAN domains 3, Zinc finger and SCAN domain-containing protein 13, Zinc finger protein 306, Zinc finger protein 309, Zinc finger protein 47 homolog, Zf47, Zfp-47.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly localizes in the nucleus. Under starvation conditions translocates to the cytoplasm, allowing expression of target genes involved in autophagy and lysosome biogenesis/function.
Protein: ACCD_STRS4
Sequence: MALFRKKDKYIRINPNRSRIESAPQAKPEVPDELFSKCPACKVILYKNDLGLEKTCQHCSYNFRITAQERRALTVDEGSFEELFTGIETTNPLDFPNYLEKLAATRQKTGLDEAVLTGKATIGGQPVALGIMDSHFIMASMGTVVGEKITRLFELAIEERLPVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTVLTDPTTGGVTASFAMEGDIILAEPQTLVGFAGRRVIESTVRENLPDDFQKAEFLQEHGFVDAIVKRQDLPATISRLLRMHGGVR
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.