PharMolix/UniProtQA huggingface dataset:
Protein: RPOA_FUSNN
Sequence: MLKIEKQAKAIKITEVKESNYKGQFIVEPLYRGYGNTLGNALRRVLLSSIPGAAIKGMRIEGVLSEFTVMDGVKEAVTEIILNVKEIVVKAESSGERRMSLSIKGPKVVKAADIVADIGLEIVNPEQVICTVTTDRTLDIEFIVDTGEGFVVSEEIDKKDWPVDYIAVDAIYTPIRKVSYEIQDTMFGRMTDFDKLTLNVETDGSIEIRDALSYAVELLKLHLDPFLEIGNKMENLRDDIEEMIEEPMDIQVIDDKSHDMKIEELDLTVRSFNCLKKAGIEEVSQLASLSLNELLKIKNLGKKSLDEILEKMKDLGYDLEKNGSPE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: CBID_METMP
Sequence: MGKIDFRLEKTFGYTTGACAAAGAFSALYFLKNNEKLRFVEILNLKGDSLIIPIKNIEKQKNTAISTVEKFSGEDIDITNGMDIKIEVTLEKLDNNSSKSSSVKIIGGDGVGIVTKSGLQVNPGEYAINPKPREMIENNLKSLLENDECVTAKISVPNGDEIAKKTLNPKLGIIGGISILGTTGIVRPMSNDAYKESLAPQIDVALAYNFENLIFVPGNIGTKHAKILLNAKEDQIIEVSNFWDYMLDKAKEKGVKDITVFGHAGKIVKLAGGIFDTHSRVADARNEILCAYTSLITQDVEMLQKILQSNTTEDIVEILTEKGILTEVFEKVSKRVVERLSLRWEKINFSCIIIDMKGNILGKSD
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: BIOB_STAAC
Sequence: MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNEVSRAN
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: SYGA_NITSB
Sequence: MITFSELLLKLQDFWAKQGCTIVQPYDFPSGAGTFHPATFLKSLDSKPWATAYVAPSRRPTDGRYGENPNRLGAYYQFQVLIKPSPDNIQDLYLKSLEALGLDWRKHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGFECDPVAVEITYGTERLAMYLQEVESVFDIVWSKNGGHIVTYADVHKRGEFEYSRYNFEVADTKMLFDWFEDASRECKRCLEEKLPLPAYDYCLLASHIFNTLDARKAISVTERQNFILKVRELAKGCAEVYKESLGELSEA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMP2B_BRUC2
Sequence: MNIKSLLLGSAAALVAASGAQAADAIVAPEPEAVEYVRVCDAYGAGYFYIPGTETCLRVHGYVRYDVKGGDDVYTGSDRKGWDKSARFALRVSTGSETELGTLKTFTELRFNYAANNSGVDGKYGNETSSGTVMEFAYIQLGGLRVGIDESEFHTFTGYLGDVINDDVISAGSYRTGKISYTFTGGNGFSAVIALEQGGDNDGGYTGTTNYHIDGYMPDVVGGLKYAGGWGSIAGVVAYDSVIEEWAAKVRGDVNITDQFSVWLQGAYSSAATPDQNYGQWGGDWAVWGGLKYQATQKAAFNLQAAHDDWGKTAVTANVAYELVPGFTVTPEVSYTKFGGEWKNTVAEDNAWGGIVRFQRSF
What is the function of this protein?
Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.
What are the official names of this protein?
Porin Omp2b.
What is the protein family that this protein belongs to?
Belongs to the alphaproteobacteria porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RXL7_STAAS
Sequence: MSKEKVARFNKQHFVVGLKETLKALKKDQVTSLIIAEDVEVYLMTRVLSQINQKNIPVSFFKSKHALGKHVGINVNATIVALIK
What are the official names of this protein?
Putative ribosomal protein L7Ae-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: DCTA_SALPA
Sequence: MKTSLFKSLYFQVLTAIAIGILLGHYYPELGAQMKPLGDAFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAQAVAVYAAQAKEQGIIAFLMDVIPGSVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGSLVQLGQLIICFYITCILFVVVVLGTIARVTGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSHMDIFHQITLLVVLLLSSKGVAGVTGSGFIVLAATISAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATVVVAKWVKELDHQKLDDVLNNRAPDGKTHEISSYSRHLCP
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMA_STRU0
Sequence: MRIADYSVTRAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEIDRSVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLIPILADTLRDFDNVQVINQDILKSDLQSQIKQFKNPDLPLKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRISAEPNTKAYGSLSIAVQYYMTAKVAFIVPKTVFVPAPNVDSAILKMVRRPEPLIEVTDEDFFFRVAKVGFIHRRKTLWNNLTSHFGKTEEIKTKLTQALELADIKPSIRGEALTIPQYGKLADALKEVGF
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_BRUSI
Sequence: MSDKAAGETKNGNGATTEPSLNILAQYVKDLSFESPGAPLSLRPREKAPSININVNVNANPLSETDFDVVLTLEAKAVDGKDILFNTELVYGGVFRIQGIPQEHMLPLLFIECPRLLFPFARQIIADATRNGGYPPLMIDPIDFAQMFQQRMAEEQAKSAVKS
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_CORGL
Sequence: MAGQKIRIRLKAYDHEAIDASARKIVETVTRTGARVVGPVPLPTEKNVYAVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RL7_CLOBB
Sequence: MTREDIIQAIKEMSVLELNELVKACEEEFGVSAAAPVAVAGAVAGGAAEEKTEFDVILASAGANKIKVIKAVREITGLGLKEAKEIVDGAPKTLKEAVSKEEAEDMKAKLAEVGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: APOL2_HUMAN
Sequence: MNPESSIFIEDYLKYFQDQVSRENLLQLLTDDEAWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQWFLKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSVGTTSGILTLLGLGLAPFTEGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARNLDQSGTNVAKVMKEFVGGNTPNVLTLVDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPPHVIGRISAEGGEQVERVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLEGAKSESAEELKKRAQELEGKLNFLTKIHEMLQPGQDQ
What is the function of this protein?
May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
What are the official names of this protein?
Apolipoprotein L2, Apolipoprotein L-II, ApoL-II.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_MYCUA
Sequence: MPVNRYRPFAEEVEHIRVTDRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIITEGAIPDDVTIQVLTQCRPELIERTFEACAGASKVIVHFYNSTSILQRRVVFRADRAAVEAIATDGARRCVEEAAKYPDTQWRFEYSPESYTGTELEYAKQVCDAVAEVIQPTPENPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAGADRIEGCLFGNGERTGNVCLATLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVPERHPYGGDLVYTAFSGSHQDAINKGLDAMEFDADAADSDMDDMLWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSRAIQEIAEGSAGEGGEVSPKEMWDAFAEEYLAPVRPLERIKQRVIAAEEDGGTTSIDATVKIDGKEAEISGSGNGPLAAFVHALGTVGFDVAVLDYSEHAMSAGDDAQAAAYVEASVAGKTVWGVGIAPSITTASLRAVVSAINRASR
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: DEOC_ECOSE
Sequence: MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_STRZJ
Sequence: MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREGFVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLGIAILSTSEGLLTDKEARQKNVGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: METQ_BACSU
Sequence: MKKLFLGALLLVFAGVMAACGSNNGAESGKKEIVVAATKTPHAEILKEAEPLLKEKGYTLKVKVLSDYKMYNKALADKEVDANYFQHIPYLEQEMKENTDYKLVNAGAVHLEPFGIYSKTYKSLKDLPDGATIILTNNVAEQGRMLAMLENAGLITLDSKVETVDATLKDIKKNPKNLEFKKVAPELTAKAYENKEGDAVFINVNYAIQNKLNPKKDAIEVESTKNNPYANIIAVRKGEEDSAKIKALMEVLHSKKIKDFIEKKYDGAVLPVSE
What is the function of this protein?
Part of the ABC transporter complex MetNPQ involved in methionine import.  Binds the methionine and transfers it to the membrane-bound permease.  It has also been shown to be involved in methionine sulfoxide transport (Probable).
What are the official names of this protein?
Methionine-binding lipoprotein MetQ.
What is the protein family that this protein belongs to?
Belongs to the NlpA lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: AB18G_ARATH
Sequence: MPRVSAEILDISHTGGNESPTLGELLKDFNDSGRKKYPGENAPTQHILDLAPAAETRSVPFLLSFNNLSYNVVLRRRFDFSRRKTASVKTLLDDITGEARDGEILAVLGGSGAGKSTLIDALAGRVAEDSLKGTVTLNGEKVLQSRLLKVISAYVMQDDLLFPMLTVKETLMFASEFRLPRSLPKSKKMERVETLIDQLGLRNAADTVIGDEGHRGVSGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTNAFMVVQVLKRIAQSGSVVIMSIHQPSARIIGLLDRLIILSHGKSVFNGSPVSLPSFFSSFGRPIPEKENITEFALDVIRELEGSSEGTRDLVEFNEKWQQNQTARATTQSRVSLKEAIAASVSRGKLVSGSSGANPISMETVSSYANPPLAETFILAKRYIKNWIRTPELIGMRIGTVMVTGLLLATVYWRLDNTPRGAQERMGFFAFGMSTMFYCCADNIPVFIQERYIFLRETTHNAYRTSSYVISHALVSLPQLLALSIAFAATTFWTVGLSGGLESFFYYCLIIYAAFWSGSSIVTFISGLIPNVMMSYMVTIAYLSYCLLLGGFYINRDRIPLYWIWFHYISLLKYPYEAVLINEFDDPSRCFVKGVQVFDGTLLAEVSHVMKVKLLDTLSGSLGTKITESTCLRTGPDLLMQQGITQLSKWDCLWITLAWGLFFRILFYLSLLFGSKNKRT
What are the official names of this protein?
ABC transporter G family member 18, ABC transporter ABCG.18, AtABCG18, Probable white-brown complex homolog protein 18, AtWBC18.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TSAD_RHOPA
Sequence: MTSEQALLVLGIETTCDETAAAVVERRADGSGRLLSNIVRSQTDEHAPFGGVVPEIAARAHVDVLDGIIAAAMNEAGVAFASLSGVAAAAGPGLIGGVIVGLTTAKAIALVHGTPLIAVNHLEAHALTPRLTDSVEFPYCLFLASGGHTQIVAVLGVGNYVRLGTTVDDAIGEAFDKIAKMLGLPYPGGPQVERAAEAGDPNRFAFPRPMLGRQDANFSLSGLKTAVRNEAGKLTPLDPQDINDLCAGFQAAVLESVADRLGAGLRLFKERFGPPKALVAAGGAAANQAIRRMLREVAAKVQTTLIVPPPALCTDNGAMIAWAGAERLALGLTDTMDTAPRARWLLDANATAPAKFANTRAGF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMPS3_MOUSE
Sequence: MGENDPPAAEAPFSFRSLFGLDDLKISPVAPDGDAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCHSSFKCIELTARCDGVSDCKNAEDEYRCVRVSGQRAALQVFTAAAWRTMCSDDWKSHYAKIACAQLGFPSYVSSDHLRVDALEEQFQGDFVSINHLLSDDKVTALHHSVYMREGCTSGHVVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHLCGGSIITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERDLKT
What is the function of this protein?
Probable serine protease that plays a role in hearing.  Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival.  Activates ENaC (in vitro).
What are the official names of this protein?
Transmembrane protease serine 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: TRPD_SERMA
Sequence: MQPILEKLYRAESMSQQESQQLFSAIVRGELEPSQLAA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: GCS2_NITMU
Sequence: MSLMPFAPSRPLSIGVELELQLLGCNDYNLAPSAPEILRRVAKRTHPGEIKPEMTRSMIEINTSVQQEYAGLVTELRALRDVVSEAGCFLNVAVAGGGTHPFQHWSEQKIFDAPRFHYLSELYGYLAKQFTIFGQHVHIGCPGPDEALHLTHMLSRYIPHFIALSASSPFVQGHDTGFASARLNSVFSFPLSGRAPFVLRWNDFEKFFAKMTGTGVVESMKDFYWDIRPKPEFGTIEVRVCDTPLTVEIAASIACYIQAMSRYIMVEQRMAPEEDDYLVYTFNRFQACRFGLEGVFIDPRTHQQRSIREDIMEMLEHISDHARELHAVEAMERIREILIVGNGTSWQRRAYASEHNLADVMQLQAELWMGN
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: CLD5_MOUSE
Sequence: MGSAALEILGLVLCLVGWVGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYESVLALSAEVQAARALTVGAVLLALVALFVTLTGAQCTTCVAPGPVKARVALTGGALYAVCGLLALVPLCWFANIVVREFYDPTVPVSQKYELGAALYIGWAASALLMCGGGLVCCGAWVCTGRPEFSFPVKYSAPRRPTANGDYDKKNYV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-5, Brain endothelial cell clone 1 protein, Lung-specific membrane protein.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: CAC1S_RAT
Sequence: MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISVVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTAILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFIRHWRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFMIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSRGLPDKSEEERSTMTKKLEQKPKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPASPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDTLLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKRCDPESDYAPGEEYACGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLRTIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPPVMANQRPLQFAEMEMEELESPVFLEDFPQNPGTHPLARANTNNANANVAYGNSSHRNSPVFSSIRYERELLEEAGRPVTREGPFSQPCSVSGVNSRSHVDKLERQMSQRRMPKGQVPPSPCQLSQEKHPVHEEGKGPRSWSTETSDSESFEERVPRNSAHKCTAPATTMLIQEALVRGGLDSLAADANFVMATGQALADACQMEPEEVEVAATELLKRESPKGGAMPREP
What is the function of this protein?
Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle.  Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca(2+) release from the sarcplasmic reticulum and ultimately results in muscle contraction.  Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.
What are the official names of this protein?
Voltage-dependent L-type calcium channel subunit alpha-1S, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, ROB1, Voltage-gated calcium channel subunit alpha Cav1.1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1S subfamily.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma, T-tubule; Multi-pass membrane protein.
Protein: KHSE_SHIFL
Sequence: MVKVYAPASSANMSVGFDVLGAAVAPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIE_ECOHS
Sequence: MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
What is the function of this protein?
Overproduction of CaiE stimulates the activity of CaiB and CaiD.
What are the official names of this protein?
Carnitine operon protein CaiE.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: FLBT_RHIME
Sequence: MKSTLRISLKSGERIFVNGAVLRVDRKVAIEFLNDVTFLLENHVLQPEDATTPLRQLYFIAQMILINPEGADQSTAMFRKSIVMLLNCFKHDEVLAELKRIDGLVTQGRAFEALKAIRGLYPIEDQILNAQELTPATVEQIRKEIAPWR
What is the function of this protein?
Has a post-transcriptional repressor function in flagellum biogenesis.  Associates with the 5'-UTR of fljK mRNA and promotes its degradation.
What are the official names of this protein?
Probable flagellum biosynthesis repressor protein FlbT.
What is the protein family that this protein belongs to?
Belongs to the FlbT family.
Protein: Y2024_PSEAE
Sequence: MSPTLTHLALHVPDLDACIAFYETFCGMRVIHRRPGKGSQIVWMAEPGQEQRFIFVIMPGGQPRNLASDDYSHFGFALSSRAAVDDLARRAEAAGCLVWAPRDEPYPVGYYCGLRDPAGNYVEFSYGQPLGPGSEALPIP
What are the official names of this protein?
Uncharacterized protein PA2024.
Protein: SPED_ECO8A
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: COXX_BDEBA
Sequence: MLRIYADLTKFGIVVFSVLAGLAGYATGFQIENPFDWKIFLETLLGIYFLSSGSLALNQVQDWKIDQKMPRTAKRPIPSGKIKPAAAGILSVGLLLVGMNMLFKLEPVAGWVGLFCVFLYNGPYTLWWKRRWVFAAVPGAIPGALPVTIGYAVANPDIFNSESLYLFLIMFLWQMPHFWVLAIRYKDDYAAGGIPTLPVALGMEKTMFQVGLYTLVYVGVALAAPMFVHASWMFVLLTFPFVFKVLQEFYRYYKSNGTERWLAFFMWLNVSMLVFIIIPVIDKWNFLFIHHN
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.