PharMolix/UniProtQA huggingface dataset:
Protein: IMMI_ECOLX
Sequence: MNRKYYFNNMWWGWVTGGYMLYMSWDYEFKYRLLFWCISLCGMVLYPVAKWYIEDTALKFTRPDFWNSGFFADTPGKMGLLAVYTGTVFILSLPLSMIYILSVIIKRLSVR
What is the function of this protein?
This protein is able to protect a cell, which harbors the plasmid ColIa-CA53 encoding colicin Ia, against colicin Ia.
What are the official names of this protein?
Colicin-Ia immunity protein.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMD_CELJU
Sequence: MAYKKPGFLGKKPVPHGKGAGRDPYVRDDSPRLTAPRREQPQPLQRNKRLGELLIDRFSHDGRGLASLDGKTLFVDGAIAGETVTARLLEDHPRFAEARVEDVILASPDRVEPPCAHYATCGGCQLQHLKPEAQLLMKQQVVLEQVHRWGGLTPKRVLPPLRSESLGYRSRARLGVWYEADSSVTLGFRQQQRKTLTNIESCSVLLPALNRLIGPLRQWLQARVANKAVTHIELVAAQSGPAVIVRHTKPLVALQRQALAELAQRESCQVWLEPNGNQGLTDLEGSPVDPHLVLDVAGLPLHFHPQDFTQVNPAVNGRMVQQALELLAPGTNDLVLDFFCGMGNFTLPMASRVARVIGLEVVEPMVTRAQANATRLGLDNLEFLKADLSQMDSPRLRQLCSQASAILLDPPRDGAKELVTQLRDLRRKGQLSAQRIVYVSCNPATLARDAALLAEAGYGLDALGVMDMFPHTSHVESMALFLYKQ
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: UBIB_PARP8
Sequence: MRFLRFLKIFFTVIRFGLDEMMLSRVNDRRVRLLLRITTIGRKFDQPPGVRLRLALESLGPIFVKFGQVLSTRRDLLRPDIATELAKLQDQVPPFDSAVAIAIIEKSLGAPVDTIFDDFERVPVASASIAQVHFATLKIGQHAGKQVAVKVLRPNMLPVIDSDLALLRDIAVWAERLWADGKRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMYWEYCTANVLVMERMVGVPISQVDTLRVAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPAHFGRYIALDFGIIGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPATTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMNEQIGAKGWYERLKIEAPQWSKTLPQLPRLIHHVLAQRHDAQQRGINDETIRQILLEQKRTNRLLQGLLMFGVAVGVGAVLARAWLAIAYGGY
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GLMU_ALTMD
Sequence: MAFSVVVLAAGKGTRMKSSLPKVLHKVGGVPMVQRIINTVRSLGADNIHLVYGHGGDQLKATVVEENLNWCLQAEQLGTGHAVQQAAPHINDDEDVLILVGDAPLIREDTLSALKAVKESCDLALLTVNLDDPTGMGRIIRENDNITAIVEHKDATEAQRAIKEINTGMMMMSGADLKRWLGELSNDNAQGEYYLTDVIAMAASEGKRIQSAQPQSAVEVEGVNNRLQLANLERALQNRQADELMTNGVTLLDPSRFDLRGTLQTGNDVIIDVNVIVEGDVTLGNNVEIGANCILRNCTIADNAVIEANSIIEEARVGEACTVGPYARLRPGAVMQKNAKVGNFVEMKKAVLGEGAKANHLTYLGDAEVGAKANIGAGTITCNYDGVNKSKTVIGENAFIGSNSSLVAPVNIGKGATVGAGSVITSTVDEAALAVARGKQRNIPNWPRPTKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2709_STAA9
Sequence: MKKQDISVKTVVAIGIGAAVFVILGRFVVIPTGFPNTNIETSYAFLALISAIFGPFAGLMTGLVGHAIKDFTTYGSAWWSWVICSGIIGCLYGWIGLKLNLSSGLFSRKSMIYFNIGQIIANIICWALIAPTLDILIYNEPANKVYTQGVISAVLNIISVGIIGTILLKAYASSQIKKGSLRKE
What are the official names of this protein?
UPF0397 protein SaurJH9_2709.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL5_STAAB
Sequence: MNRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEARELLANFGMPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RAB13_MOUSE
Sequence: MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKIRTVDIEGKRIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRQVQREQAEKLAREHRIRFFETSAKSSVNVDEAFSSLARDILLKTGGRRSGTNSKPSSTGLKTSDKKKNKCLLG
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  That Rab is involved in endocytic recycling and regulates the transport to the plasma membrane of transmembrane proteins like the tight junction protein OCLN/occludin.  Thereby, it regulates the assembly and the activity of tight junctions.  Moreover, it may also regulate tight junction assembly by activating the PKA signaling pathway and by reorganizing the actin cytoskeleton through the activation of the downstream effectors PRKACA and MICALL2 respectively.  Through its role in tight junction assembly, may play a role in the establishment of Sertoli cell barrier.  Plays also a role in angiogenesis through regulation of endothelial cells chemotaxis.  Also involved in neurite outgrowth.  Has also been proposed to play a role in post-Golgi membrane trafficking from the TGN to the recycling endosome.  Finally, it has been involved in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore may play a role in glucose homeostasis.
What are the official names of this protein?
Ras-related protein Rab-13.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Cell junction, tight junction. Golgi apparatus, trans-Golgi network membrane. Recycling endosome membrane. Cell projection, lamellipodium. Note=Tight junctions or associated with vesicles scattered throughout the cytoplasm in cells lacking tight junctions (By similarity). Relocalizes to the leading edge of lamellipodia in migrating endothelial cells (PubMed:21543326).
Protein: DEOD_EDWI9
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKHIAETFLQDVRQVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYAKELITDFGVKKIIRVGSCGAVSMDVKLRDVVIGMGACTDSKVNRLRFKDNDFAAIADFDMVRNAADAAKAKGIDARVGNLFSADLFYSPDPTMFDVMEKYGILGVEMEAAGIYGVAAEFGVKALTICTVSDHIRTHEQTTAAERQTTFNDMIEIALESVLLGD
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: PUR4_VIBCH
Sequence: MRILRGSPALSEFRVNKLLTACREQQLPVTGIYAEFMHFADLKAELNPQELEKLEKLLTYGPTIQEHEPQGLLLLVTPRPGTISPWSSKATDIAHNCGLHGIKRLERGTAYYVEAETALTAAQIATLEALLHDRMMEVVFAELTDAQQLFSVAEPAPMSQVDVLAGGRRALEEANVSLGLALAEDEIDYLVESFTKLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVKQDKSLFKMIKNTFEQTPDYVLSAYKDNAAVMTGSTVGRFFPDPESRQYTYHHEDAHILMKVETHNHPTAISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPWESDFGKPSRIVNALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNIRAEHIQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEMERRCQEVIDRCWQLGDKNPIAFIHDVGAGGISNALPELVNDGDRGGKFQLRNVPNDEPGMSPLEIWCNESQERYVLAVAAEDMPLFDAICQRERAPYAVVGEATEERHLTLEDSHFANTPIDMPMDILLGKPPKMHREASTLKVSSPALERSGIELNEAVDRVLRLPAVAEKTFLITIGDRSVTGLVARDQMVGPWQVPVANCAVTAASFDSYHGEAMSMGERTPVALLDFGASARLAVGEAITNIAATDIGELKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGITIPVGKDSMSMKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGETSLILIDLGNGQNRLGATALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRNDKLVAYHDKGDGGLLVTLAEMAFAGHCGIKANIETLGDDALAALFNEELGAVVQVKNDELNAVLATLAAHGLEACAHVIGEVEASDRLLITCGEEVLIERSRTELRTIWAEMTHKMQALRDNSACADQEFAAKQDNRDPGLNAKLTYDVQADVAAPYIAKGVRPKMAILREQGVNSHVEMAAAFDRAGFDAVDVHMSDILTGQTVLDAYQGLVACGGFSYGDVLGAGEGWAKSILFNAQAREQFEQFFQRKDTFSLGVCNGCQMLSNLRDLIPGAELWPRFVRNESDRFEARFSLVEVQKSPSLFFSEMAGSRMPIAVSHGEGRVEVRDAQHLAAIEQSGTVAIRFVDNFGQPTQAYPSNPNGSPNAITGLTTQDGRVTIMMPHPERVFRTVANSWHPDNWGENGAWMRMFQNARKYFG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIH_BOVIN
Sequence: MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM
What is the function of this protein?
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.  Participates in pre-mRNA splicing.  May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.  May act as a chaperone.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase H, PPIase H, Rotamase H.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Note=Colocalizes with spliceosomal snRNPs. A small proportion may also be cytoplasmic (By similarity).
Protein: UPPP_BORA1
Sequence: MTDSTLYFVKAFFLGIIEGLTEFIPVSSTGHLILFGDWINFESGSGKVFEVVIQLGAILAVMWIFRARLWQLIRGTLSGQRQEMLFTRNLLLAFFPAAIIGAIFIKAIKQTFYHPGVVAVTLVLGGLIMLWVERRAPRSDGSASETATEERATAHSLEEISWKQALGVGVAQCLAMIPGTSRSGATIIGGMVAGIQRKTATEFSFFLAMPTMLGAAVYDMYRNIDLLTSHDLGAIAVGFVAAFLSALLVVRAVLRFVANHTYRGFAWYRIALGVVVAAWLAF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1462_ACTSZ
Sequence: MFKTTREKGASFEQQARLFLEQQGLRFIAANQHFKCGELDLIMADGDTYVFVEVRQRKTILFGSAVESVDWRKQQKWLDAANMWLAQRNLSLEDADCRFDLIAFGRTASDIEWLPNFLD
What are the official names of this protein?
UPF0102 protein Asuc_1462.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: TSR3_MOUSE
Sequence: MGRKKVARGSRKESGRVRRPSGRSLDAFAEEVGAALRASVQPEEAEDQGGPGPAALPCALAMWELGHCDPKRCTGRKLARLGLVRCLRLSQRFGGLVLSPVGTEYVSPADRQLVAQSGVAVIDCSWAKLDDTPFQKMRGSHLRLLPYLVAANPVNYGRPCKLSCVEAFAAAFCIVGFSDLAVILLRKFKWGKGFLDLNRELLDKYAACRGPEEVLQAEQGYLASTRDTPEEDIDPFDVDSGREFVNLNRPVASTRLPEDMDDTDGSEEHSEDSEEDSDECEEPGPGANGGDSNYSGAEETPEQEAQARDSTEIWKGIKKRQRD
What is the function of this protein?
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA.  It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
What are the official names of this protein?
18S rRNA aminocarboxypropyltransferase, 20S S rRNA accumulation protein 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. TSR3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_CHRVO
Sequence: MTSLKKIYSGKVRDLYEIDDQRMLMIATDRLSAFDVILDDPIPAKGQILTAISNFWFDKLKDVVPNHLTGDQPEDVVAAADLPQVEGRAVVAKRLKAVPIEAVVRGYLAGSGWKEYRQSGSVCGIALPAGLKEADKLPEPIFTPSTKAAVGDHDENISFAQCEAIVGAELAAKVRDTAILLYQTAAEYAATRGIIICDTKFEFGLDENGTLTLMDEALTPDSSRFWPADSYQPGSNPPSFDKQFVRDWLEASGWNKQAPAPAVPLDVREKTAAKYREALEKLAG
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PNP_COPPD
Sequence: MIERKKIEVTGTVAGKKVIFQSGFLALQANGAVLARFGDTVALSTVLMSSEPKLDIDFFPLTVDYEEKSYAVGKIPGGFFKKEGRPTDMEILKARLIDRSIRPMFPDGMRNEVQVLNMILAADMENPPDIVALNGTAAALAVSDIPIPELIAGVRVGYIDGEYVLNPTFAEMSESQLDLVVAGTRDSIVMIEAGAAEVDKSILIGGLKFAQEGIRQIIDLIAELKEKVGRPKAEITVVSFPQEQLDFMRNHEDRFRAALITPIKQERERAVSELKKALFQEMLEVFPDLDEAMFNLMFGEVEKEVVRAYMKSTRKRVDGRAFDEIRPLYAESSVLPKVHGSGLFIRGQTQVLSTVTLGSFSDVQFIDAIGLEEFKRFMHQYDFPPFSTGEVKPRRGPSRREIGHGALVERALSYLIPSEEVFPYTIRVVSEVLESNGSTSMASTCASSIALMSAGVPMARHVGGIAMGLIEYNDENVVLTDIQGLEDHLGDMDFKVAGTREGITALQLDVKVKGISVETLDKAIDQAEVARSKILDVLYDAIPSPRPLSETAPRIVKIEIPVDKIGEVIGPGGRNVKRITQETGATIDIREDGVAFVKGLTDESVNMAKQQVEMIVKDPEVGEELTARVVRVTPSYAIVEIAPGKTGLLHVSEVSETRIRSLEDVLSVGQTIKVWVKEKDGEGRLRFSAKEKKSEAH
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_LEPCP
Sequence: MFRTLLKSKIHRAVVTHCELHYEGSCGIDEDLLDAANLCENEQIHVWNINNGERFVTYVIKAPRGSGIISLNGSAARRASAGDLVIIAAFAQVHEEQVPTHQPKLVFMDEANRIKELRSEPQNPPQTSPLR
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS29_MOUSE
Sequence: MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
40S ribosomal protein S29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: KPC1_NEUCR
Sequence: MNDEDKVHDISKKIEREKALINAAQAMRQQTNNEQVRSKLDTQMREGRRNLEFFEEKLRELQMRRLGHGVDNMSLGASPMSGSHRQSVDDFEGYGAPSPPPKEDVRGHSSHQSQGSGPLMPASAPYPGGPPDSNVPRARPNYTRLDLIKFDTPHLGPRIQLMLSQIQFKLNVEEQYLKGIEKMVQLYQMEGDKKSKLDAAAKRVESKQKIVLLKQALKRYEELHIDIDVDGPDDDSINLPALRKPLSGTLSIRILAVKDVDHAPLGRFARSPETFIAVKAEDIVVARTKPSRNDKWEAEFHTFPVDKTNEIEFTVYDKPAEHPVPIAMLWVRISDIVEELRRKKIEAEMTSAGWVSADRVGSRAPPPQFPMGAQSPQFAAPPTSPGSQEQNTMIPPQAPPPSQVVSQPVDGWFNLEPYGQIHLSFNFIKGARPQGMDRLGRKGAVRQRKEEVHEMYGHKFVQKQFYNIMRCALCGDFLKYSAGMQCEDCKYTCHTKCYTSVVTKCISKSNAETDPDEEKINHRIPHRFIPFSNLTANWCCHCGYMLPIGSKKNSRKCSECALTAHAQCVHLVPDFCGMSMAVANQILEGMRTQKKTHKDKASSMSERTLRPGSKTSISSGSIAQASTYSGSTAYTSIASPEATEAAKLMYSQTTPRPGGPDRTSTSSTTASAAAAAAMAPKHSSQPSQAGSIPDFGGSPGYGRPDSRDDEYSAQQQQGYGSPQQRKYNPADYANIDAYSSPQARPQQQQQQQQQTPQQVSPMYQQNPQTPISKPQPVAPSYDNQVVPSASGVPVPTKKPLPSATDPGTGMRIGLDHFNFLAVLGKGNFGKVMLAETKKSRKLYAIKVLKKEFIIENDEVESIRSEKRVFLIANRERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQRGMFGTKRAQFYAAEVCLALKYFHENGVIYRDLKLDNILLTLDGHIKIADYGLCKEDMWYGSTTSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLLTREPDQRLGSGPTDAQEIMSQPFFRNINWDDIYHKRVQPPFLPQIKSATDTSNFDSEFTSVTPVLTPVQSVLSQAMQEEFRGFSYTADFE
What are the official names of this protein?
Protein kinase C-like.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Protein: RS2_BORDL
Sequence: MAVITMKSLLEAGVHFGHQVKRLDPRMKRFIFSERNEIHILDLQKTLQGIKDSYELVQSVIKNGKKVLFVGTKKQASEIIEQEAKRSEMPYVNNRWLGGMLSNFNTIKKSVQKLKKLEKMEVDGTFEMISKKEVSQINREKLKLAKNLTGIKDMEELPGAIFIIDPKREQIVINEARKLGIPIIAVVDTNCNPDVIDCPIPGNDDAIRSVALFTKIISDAILESDKEVGIQIVENLNEEDLMSEIEVKNERKES
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CANB_DROME
Sequence: MYGIDNYPKNYHASGIGLVNLAALGYSKNEVSGGNEGGGAPKPKAGLYPSLPYPSSESVGGMPYVVKQTSHAQNASYAGPTMGMGMPVPEAPSAPAPYPSATPYPGSGLYPSLPSANVSSLPYPTAPMAPYPTGMPYPTGMPQPNLPYPAAPLAPYPSAMPGLPGMPMPYAPMPTSPAPQHNIGFPALPYPTAPPPESAPTQEEEPSVGVAELSFTSVKVPENQNMFWMGRKATSARQNSVSKGDFQSLRDSCLANGTMFEDPDFPATNASLMYSRRPDRYYEWLRPGDIADDPQFFVEGYSRFDVQQGELGDCWLLAAAANLTQDSTLFFRVIPPDQDFQENYAGIFHFKFWQYGKWVEVVIDDRLPTYNGELIYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKEAPPNLFSIMMKAAERGSMMGCSLEPDPHVLEAETPQGLIRGHAYSITKVCLMDISTPNRQGKLPMIRMRNPWGNDAEWSGPWSDSSPEWRFIPEHTKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQHSSRRKWEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYIISLEDPDDEDDDGKCTAIVALMQKNRRSKRNVGIDCLTIGFAIYHLTDRDMQVKPQGLNFFKYRASVARSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETRNNMEENDDEVGFGETDDRIAPSLPPPTPKEEDDPQRIALRRLFDSVAGSDEEVDWQELKRILDHSMRDVMVGSDGFSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALAHRYGSREGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWLERTIYS
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease.
What are the official names of this protein?
Calpain-B, Calcium-activated neutral proteinase B, CANP B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=Translocates to intracellular membranes when calcium levels are increased.
Protein: AP1_ASPOR
Sequence: MADYNTLYHQGLYLSPDQQDLLLAALSSNQPPQKQQNDKQRSQAKTDPDSTPGNMSSGSFSMSPGFNKTHPGSGGLGYGDDESPFLDFNPELDFDFPGSENLIGDLPGSLPSEEHEVGEKRKDMSDNENEESGKKRRESDDKAAKKPGRKPLTSEPTSKRKAQNRAAQRAFRERKEKHLKDLETKVDELQKASDDANQENGLLRAQVERLQVELREYRKRLSWLTTGSGISAMSAIPSAHSRNLYGLNNNDFMFDFPKFGDLPGGHIFNGPLTKSNQNKPRDGSSPATSDSQVPGVMTRETLNGSNNRGMPTAKAANGVSNNPSPKVPSVYNIRQSASSHDSSNSCSPSSSSDSHQSQMLSSNGTSPEPSSNSPATKLNDSVQNHHACTYSTIDAVRGKSESVSNTPSQPNNNYEQTPGPGLDLLAQQNGGQFDPVLFGDWREPQDAILSQDFGTFFDDAFPLPDLGSPSHNFNEVANPQPPKKDLIAEIDNKLDEEVVPGEDKSQMLSCTKIWDRLQSMEKFRNGEIDVDNLCSELRTKARCSEGGVVVNQKDVEDIMGRVK
What is the function of this protein?
Transcription activator involved in oxidative stress response and redox homeostasis (PubMed:31366149).  Regulates the transcription of genes encoding antioxidant enzymes and components of the cellular thiol-reducing pathways (By similarity).
What are the official names of this protein?
AP-1-like transcription factor yap1, BZIP domain-containing transcription factor yap1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. YAP subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The nuclear localization is oxidative stress-dependent and oxidized yap1 is found predominantly in the nucleus, while reduced yap1 is continuously exported to the cytoplasm.
Protein: ILVC_PSEPF
Sequence: MKVFYDKDCDLSIIQGKKVAIIGYGSQGHAQACNLKDSGVDVTVGLRKGSATVAKAEAHGLKVTDVAAAVAGADLVMILTPDEFQSQLYKNEIEPNIKKGATLAFSHGFAIHYNQVVPRADLDVIMIAPKAPGHTVRSEFVKGGGIPDLIAIYQDASGNAKNVALSYAAGVGGGRTGIIETTFKDETETDLFGEQAVLCGGTVELVKAGFETLVEAGYAPEMAYFECLHELKLIVDLMYEGGIANMNYSISNNAEYGEYVTGPEVINAESRQAMRNALKRIQDGEYAKMFISEGATGYPSMTAKRRNNAAHGIEIIGEQLRSMMPWIGANKIVDKAKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: EFP_COLP3
Sequence: MANFSTNQFKAGLKIMLDGEPCNILENELVKPGKGQAFSRVKIRKLVSGKVLEKTFKSGETVEGADVMEVELAYLYADGEFWHFMNNETFEQIGAEEKALGETVKWLVEGDICTITLWNGTPITVTAANFVEIDITETDPGLKGDTAGTGGKPATLATGAVVRVPLFVQIGEKVRIDTRSGEYVSRATKAQ
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_SYNAS
Sequence: MKHDSFIAREGIPFIIAFGLTTLLAVFFLEQSWIAVLPLTATLFTCWFFRNPERHTPEGEKLIVSPADGKVIRIDEDFHHEMLSQPCSKVSIFMNVFNVHVNRVPYSGKVTKISYSPGRFLSANLDKASEQNERNAILVRTSDGKEIMTIQIAGLIARRIVCWVREEDVVKRGERFGMIRFGSRLEVFMPKETKILVTVGEKVKAGESPLGTF
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNFE_BUCA5
Sequence: MNIKNFLNNRLWKNNSSLVQLLGLCPVLAMTTNAINAIGLGMTTTLVLTITNTIISSFRKIIPKDLRIPIYMMIISSVVTSIEMLLHAYTFNLYQSLGIFIPLIVTNCIIVGRADLIAYKSSIVESFFDGIFIGLGSMFAMFAVGSIREILGNGTLFFGANKIISNIHSSVFFTLLDKKFTIILAVFPPGGFLILGFLIAIKNFIDLYYKKNTIKNIEQCSCSNKIK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.