PharMolix/UniProtQA huggingface dataset:
Protein: MURE_BUCAI
Sequence: MNKICLKYLLLPWIKNIPKKYISNLKMDSRTLTPGDLFIAVPGIKKDGRHFIVQAINKKAAAILCETKKKDKHGIFKYIKNVILIYFFKLSENVSLLANRFYKEPGKRLKIIGITGTNGKTTVTQLINQWSTILGTKTATMGTLGNGFYNSLQPTNNTTSSPIFIQLFLSKVLEKQAELVTMEVSSHGLIQHRVKEVPFYIAIFTNLTQDHLDYHENLEKYESAKWLLFSTHKVKKIILNADDQYGKIWLKKLLNFYTVAVTIQNRKQKKYSTKWINATNIEQNNNSIYITFESSWGTGRISSCLIGRFNVTNLLLSLACLLELGYSLSDLIHTSEKIIPVQGRMELFSYVKKPTFIIDYAHTPDALKKTLNAIHSHYQRYIWCIFGCGGERDQKKRPIMGAIAEKMSDKVIITNDNPRNEKEKKIIQDILNGCKNKEKILIIPDRKKAISYAYFGAKYHHIILIAGKGHEEKQIIQNRSINYSDKKIVLNLLGKNI
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUCM_SALHS
Sequence: MLKTISPLISPTLLKVLAEMGHGDEIIFSDAHFPAHSLGPQVIRADGLSVSDLLRAIIPLFELDSYAPPLVMMAAVEGDTLDPSVEARYRDALSLEAPCPDIVRIDRYAFYERAQKAFAIVITGECAKYGNILLKKGVTP
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRBI_RHIRD
Sequence: MVQSLNLGGAQNSQAASGIRRINRLPIVVVIVLAVAFLGIIFYGLASRGLYFGRDKGPESSSGEPASTFADQIKRGVTDGIIGEPQQQTTFQPTPVETKQVDEKASNPFTPTPEQRRGQELEPEAVWRARLEREQQEQYLRERQRQRMARLQANDAAYDAPLAIDRGKLEARTATDDTSAANTSTAISPTAGASDLYAAALRAGLGGQNIDPNGQKSKEDFFNTDLKDLGYLPNRVVPQQSLYELKRGSVIPATLITGINSDLPGRITAQVSQNVYDSATGHRLLIPQGTKLFGRYDSKVSFGQSRVLVVWSDIIFPNGSTLQIVGMAGTDAEGYGGFKDKVNNHYFKTFGSAVMIALIGTGIDMSVPQSSTLATQDTASDAARRNFAETFGRVADRTIQRNMDVQPTLEIRPGYKFNVLVDQDIIFNGIYRN
What are the official names of this protein?
Conjugal transfer protein TrbI.
What is the protein family that this protein belongs to?
Belongs to the TrbI/VirB10 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RNF10_MOUSE
Sequence: MPQSSPSAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSNGSKRYNRKREPSYPKNENFSNQSRRSNSQKSKTFNKMPPQRGGGSSKPFSSSSNGGRRDEVAEAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQAGHFEGSGHGGWGKRNKWGHKPFNKELFLQANCQFVVSEDQDYAAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESRQYAVGDTITMQLMKREKGVLVALPKSKWVNVDHPINLGDEQLSQYSKLLLASKEQVLHRVVLEEKGALEQQLAEEKHTPESCFIEAAIQEVKIREEALSGVAGGGGEVTGVVAALEHLVLMAPLATESAFQPRKGVLEYLSAFDDEAAQVCSLDPPGPLALPLVEEEEAVSEPEACEDAEVADDSLGEGTVGPEMSQEEPITKPGFTQLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLEQSPEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKKAREERRRERRIEMEENKRQGRYPEVHIPLENLQQFPAFNSYTCPSDSALGPTSTEGHGALSLSPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEDDSPFLSFAQMLRVGKAKADGWPKTAPKKDDNSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLDTPATSDPLSEDRGGKKRKRQKQKLLFSTSVVHTK
What is the function of this protein?
Transcriptional factor involved in the regulation of MAG (Myelin-associated glycoprotein) expression and myelin formation in Schwann cells.
What are the official names of this protein?
RING finger protein 10, Sid 2705.
What is the protein family that this protein belongs to?
Belongs to the RNF10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y3268_MYCTU
Sequence: MTTPTTLSGAILDPMLRADPVGPRITYYDDATGERIELSAVTLANWAAKTGNLLRDELAAGPASRVAILLPAHWQTAAVLFGVWWIGAQAILDDSPADVALCTADRLAEADAVVNSAAVAGEVAVLSLDPFGRPATGLPVGVTDYATAVRVHGDQIVPEHNPGPVLAGRSVEQILRDCAASAAARGLTAADRVLSTASWAGPDELVDGLLAILAAGASLVQVANPDPAMLQRRIATEKVTRVL
What are the official names of this protein?
TIGR03089 family protein.
What is the protein family that this protein belongs to?
Belongs to the TIGR03089 family.
Protein: RRF_ECOSM
Sequence: MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDVQKLTDAAIKKIEAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
Protein: RL22_KINRD
Sequence: MEAKAQTRYLRVTPQKARRVVDLVRGKQATEAVAVLSFAPQSAAEPVRKLVESAMANAKFHADKHSEAFDPAEYVVKAIHVDEGPTMKRFRPRAQGRAGRILKRTSHITVVVAPAVKGAKKTRRTR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SG1C1_MOUSE
Sequence: MKGSSALLLVALSLLCVCGLTRAEDDNEFFMEFLQTLLVGTPEELYEGPLGKYNVNDMAKSALRELKSCIDELQPVHKEQLVKLLVQVLDAQEDT
What are the official names of this protein?
Secretoglobin family 1C member 1, Secretoglobin RYD5.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF2_NITMU
Sequence: MLIDGFTVVAQIVNFLILVWLLKRFFYRPILDALDERENRIASELAAATGKQREAEAELHRFRQKNEEFDQRREVLLTTVTDEVRAERQRLMEAAHADADRIRISRNEAQQREYQVLHDAIERRTCAEVLAITRKVLADLAGTTLEIHMTEAFIRRLRTLGPEEKAQLAVALQAGGVESGHSATFQVFPPIVGQGSPSGIAVILVRSAFELPAEQQEKISTVIRETLKEEVRFNFGVEPNLISGIEMIAGGHKVAWSVAGYLASLEEEVSRLLNAKGAVGEGEAKSSTAAL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TTPA_HUMAN
Sequence: MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ
What is the function of this protein?
Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells (PubMed:7887897).  Binds both phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate; the resulting conformation change is important for the release of the bound alpha-tocopherol (By similarity).
What are the official names of this protein?
Alpha-tocopherol transfer protein, Alpha-TTP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUB_SALTI
Sequence: MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIATLGDRVEVTPGLKIRIDGHLISVKESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDESKLRDLSRGVQLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDFAQTNYLRGLVELPPETSSKVAVEKDRRRMKANQIRRAVKRHSQIAGGRRSGGRNNNG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase B, 23S rRNA pseudouridine(2605) synthase, rRNA pseudouridylate synthase B, rRNA-uridine isomerase B.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: RPOA_STAS1
Sequence: MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAIDNVVEDVSTIIMNIKKLALKIYSEEDKTLEIDVKDEGDVTASDITHDSDVEILNPEIKIATVSKGGHLKIRLVANKGRGYALAEQNKTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKILTEHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PYRB_BACC2
Sequence: MSHLLTMSELSEVEISEILKDAEDFANGKESKTTEQTFVANLFFENSTRTRFSFEVAEKRLGLDVLNFSADASSVQKGETLYDTIRTLESIGTKAVIVRHEQDRYFDELKDQVNIPILNAGDGCGNHPTQCLLDLLTIKQEFGRFEGLKIAIVGDVRHSRVARSNAEALTKLGATIYFASPEEWKDEDSTFGTYKPLDELVPEVDVMMLLRVQHERHDHYETDIMKEYHERHGLTVEREKRMKEGSIIMHPAPVNRDVEVASELVECERSRIFKQMENGVYVRMAVLKRALPNVLGGMKHELLV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RS8E_METM6
Sequence: MAIWQGASRRLSTGAKVWRAAKKHKREMGRPAAETQVSDRIKRKIVRCRGANLKVKLEKTNYANVFDQANKVCKKVAVTKVLDNKANKHYIRRNVMTKGAIIETEMGKAKVTSRPGQDGVVNAVLLTE
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: MRAZ_STAAW
Sequence: MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS10_BORAP
Sequence: MIAKDKIRVRLFSFDVKILDQSAESIVKAVQKAKAQIKGPIPLPTKIKKYTVLRSPHVNKKSREQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RL27_STAAB
Sequence: MLKLNLQFFASKKGVSSTKNGRDSESKRLGAKRADGQFVTGGSILYRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: COFH_METAR
Sequence: MLKDIYERSLSGEITIEDARKLLEANPFELFDTADQLRKEIVGDNVTYIVNRNINFTDFCVGTCKFCSFKNNKGFRLTLDEILQRVGAAKETGSTEVCIQGGLTEDMYLEDYAGMIRAIKSKYDIHTHAFSPMEVYHMSRMSGVTVEESLKTLKVAGLNSMPGTAAEILDDEIRSVICPGKLSTSEWVDVVSTAHRVGIPTTATIMYGHIETWEHRLKHLFIVRDVQRQTHGITEFVPLTFMHENNSLSGKSMGASGMDDLRMYALARIIFGRDIPNVQASWVKLGTKLAQVALNCGANDVGGTLMEENISKSAGSKSGEYLSPDDLQAMIKAAGRIPRQRNTLYKLLG
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: RR11_PINTH
Sequence: MSKTIKRIGSRRNEHRVLKGVIYVQASFNNTIVTATDVRGQVLSWSSAGACGFKGTRRGTPFAAQTAAENVIRALMDRGMERVEVMISGPGRGRDTALRTIRRSGILLSFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS21_ANAD2
Sequence: MTGVRVKDGESFENAMKRFKKQCEKAGILSEIRKREHYEKPSVKRKKKALAAKKRALKKMRKGF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: DABA_ROSDO
Sequence: MNTNSELSLENLNAAGDAAARAIPPLWPLASSVAVNPYLGQTAETLALAGARLGRVGGVPVTMPRAWYAARIADGTITDADLSAALAVNPTAAADLEALKAHAEQPESAQKPLPTLADLAADASGIDWPGILADRIGLWAAGYFDQGQALWAAPHRRGAYDAWRQYATHDLTPEIAGLSGFAQFVSETPDTADQASTRAANRLGLSDAALETYLHQLLFTLGGWAQVARYRLWQAELAGKSDATITDMLTIRLLWEEALFAQYEEEIGAEWEKVVAAHAAPVASDADLQVNAVLQEAWERAGQRDLAETFSMPAPKADDTRPALQAAFCIDVRSEVFRRALESLTPDIKTLGFAGFFGLTPAHKGFASDVDELRLPVLLNPGLTSTSQGDDAEADQTARFKARASRAWGRFKLAAVSSFAFVEATGPIYAGKLVRDALNMAPNDVPGGPMPRLDPSVDLAAQTDAAETILRAMSFTDNFARLVVLAGHGANVVNNPFASGLHCGACGGYSGEVNARLLAGLLNNVDVRRGLVERGITIPDDTIFVGALHDTTTDAMTLYEADHPSKAHAADLKQAKAWFLSAGSVTRAERALRLPRAEGTDDINLRSRDWAETRPEWALAGCKAFVAAPRQRTAGRSLEGRAFLHDYDWQQDKGFGVLELIMTAPVVVASWISLQYYGSTVSPDVFGSGNKLLHNVTGGIGVVEGNGGTLRTGLPWQSVHEGEDFAHEPLRLSVCIEAPREAMSDILKRHDGVRALFDNRWLHLFALDENGQMAWRYEGDLEWSQMPVASEAIPETEVAA
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBA4_ASPNC
Sequence: MNGVEQTCASLRTQIAATEAKLADLKRELEIAEQAAASHKQNAADAEGGSERRWPLLDEEYRRYGRQMIVPQLGIQGQLKLRSAKVLIVGAGGLGCPAALYLAGAGVGTLGLVDGDAVESSNLHRQVLHRTRNIGKLKVDSAIEYLKELNPHSKYIAHREHLAPEAAPEIFSNYDLILDCTDNPATRYLISDTAVLLGKPLVSASALRTEGQLMVLNNPPRPAGDKTGGPCYRCVFPKPPPANTVTSCADGGIVGPVVGTMGVLQALEAIKVITADETTTPPPPSLHIFSAYSTPLFRTIKLRSRRPNCAVCSAEASVTVDTVRSGSTDYIFFCGTTGPENLLSPEERITPLEYRTRHHDKEEKEPTIIDVREKVQYDICSLENSINIPISTILASASSSMSNGDSLADGVPALPSWVPPDVASSQSTDPVYVVCRLGNDSQVAVKKLKELGLDQGGKRVVADIRGGFRAWKEQVDPEWPEY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a.  Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions (By similarity).
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase uba4, Common component for nitrate reductase and xanthine dehydrogenase protein F, Ubiquitin-like protein activator 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMDH_STAAW
Sequence: MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKAKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: HUTI_TREDE
Sequence: MTLFISDSIFSSTEKKGVDFDKAFAGYIVVENGLIQKVGKGDAPESLKSQAEKIIDARGKTITAGLVDAHTHLVHGGSREHELAMKLAGKTYLEIHASGGGIFSTVRATRAASKEELTQKALTSLDRMLIHGTTTAESKSGYGLDMETEIKCLEINSYLNKNHPIDIVSTYMGAHATPPEFKDNKEGYIKFMIEEVMPEVKKRGLAEFSDAFCEDKIFSVEETERIMKAAADLGFKLKLHADEIIPLKGAELAAKMNAHSAEHLMAISDEGITALAKSGTVAVLLPATSFFLMSPIYAPAKKMIEEGVRVALATDYNPGSSPTENLQMAMWAACYKMKLLPAQILRGVTINAAYAIDREKTIGSIEEGKQADLVIFDAPNIDFLVYHFGVNSVDQVWKKGKLVAEKGRLVYKN
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_METTP
Sequence: MIVVYSLGGSVLAAQDSAGLKRYAEALRTIARDNQVYVVVGGGALAREYIGKARDVGASEALCDSIGILATRMNAALLAAALDGSAPFRVPESYDDAIEASKTYRMVVMGGVSPGQTTDAVAALLAEYTRATLLVIATSVNGVYTSDPEKDPGAVKIPRMGAKDLSRMMSQIELKAGSKSPVDPLAAKIIERSHIPTVVVDGRNVANLIRAIDGTHDGTEIRS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_VIBCM
Sequence: MEKFRVIGSTQPLQGEVTISGAKNAALPILFASILAEEPVEVANVPHLRDIDTTMELLERLGAKVERNGSVHVDAGPINQYCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHIHGLEQLGATITLEDGYVKAHVDGRLQGAHIVMDKVSVGATITIMCAATLAEGTTVLDNAAREPEIVDTAMFLNKLGAKISGAGTDSITIEGVERLGGGKHAVVPDRIETGTFLVAAAVSRGKIVCRNTHAHLLEAVLAKLEEAGAEIECGEDWISLDMTGRELKAVTVRTAPHPGFPTDMQAQFTLLNMMAKGGGVITETIFENRFMHVPELKRMGAKAEIEGNTVICGDVDRLSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIDRGYERIEDKLSALGANIERFRD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_STRPJ
Sequence: MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNTNVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YABA_STRMU
Sequence: MDKKDLFDVFDGFSQNLMETLAEAEALKKQVQDLVEQNASLRLENDKLRDRLSHFSQMEESDPSSKAISSRKENLENIYEDGFHICTFFYGQRRENNEDCAFCMELLYRE
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: PPR35_DROME
Sequence: MPHKRRNRVHANQRNFTARRVSVAKLSSAPPNVLVESCNGSHADNSSPDSPKAKEGAMTNGKNPEIKLAVPKCNTTVRKQNEAHIISNIKLDMNLNKDSNFIAPQITKKMNFAPNRVVFGVLVPLNVNDSVLVPHNRKPDALKHTSKESESCKAISEPQLADYAEKVDPMIMAVKEPVLHLDWEPGPFDFFGAYRRTYN
What is the function of this protein?
Participates in the later stages of centriole assembly through the interaction with Ana3 leading to the centriole to centrosome conversion in somatic cells.
What are the official names of this protein?
Protein PPP1R35 homolog, Protein Rcd4, Reduction in Cnn dots 4 protein.
What is the protein family that this protein belongs to?
Belongs to the PPP1R35 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the more distal part of the lumen of the centriole. Recruited into zone I during interphase after the formation of the cartwheel at the end of mitosis (PubMed:32543652). The Rcd4 recruitment to the daughter centriole is dependent on Ana3 (PubMed:32543652).
Protein: TRUA_STREM
Sequence: MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGIQIHGAGITDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHARYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAAGTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQIRLVLESKNRQLAGPTAAGNGLYLKEIIYEE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RECF_NATTJ
Sequence: MKLTELCLKNFRNYSNLKLNFKKPIILFFGANAQGKTNLLEAIYYLATGKSHRAQKEKELIRWETSGFYLKGELEKEQAQYTLEIITNYQNGKNKNLKVNNLSQTNTRNFLKTMNVVIFSPEDLMLVKGTPDNRRRFIDQEITQVDPSYDFYLKNYFKALRQRNKLLKTYQDKNTLAQHLPPWNQQLVHYGSKIILKREEVIHKIRLLARLIYRKITNQTENLELDYSPSLEFEDCKFREQLSGEKLAHKFLNTLNENLQSDIEKRTTSIGPHRDDLIFKINNKDARQFGSQGQQRTTVLALKMAELEMIKGEKGEFPILLLDDVLSELDDNRKKHLLNLTEGRVQTFVTSTSMEDFNGDVDIKAKSQVFRIDNGEAVKLNAGNQE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQF6_CAEEL
Sequence: MGAKTEFRSSEPITDSERSQINSVRAMLQEKLPDGIPDDVNTDLNLCRWIRGYHGDTEKLVKNFATYLASRKAAGFVGNDFAEKFFELPSIAPFLQFIASSRLQDRQWSDEHNAFLFVERAWSQPKEFIKTFKTSDYLLHCFGYSEMLQQLILRREKKQSADKGPVQFIVIFDLNTVNITDYVNPMSGYMKLWQIRSELWQDWFPEMVQRIYLTNPPRLLGLLWKVARVFLSEENLKRIEIISDKSDLAGKFLPPWLVPKEYGGEFVNTVPPGDETGVSVRRKITSADYYKPYQHYKEHGIDRPKSSHKDVSPAEKFVFKIQVPNGKKLLWDFTASGELQFAIFRGNNRNDLVFPSLHLITNKLNEEGSLDNVSDSEISFEFQNLSGYFTLKLEYTVAII
What are the official names of this protein?
CRAL-TRIO domain-containing protein C34C12.6.
Protein: UBIC_BURTA
Sequence: MRFDAADAHWRETPRPGASGAQKDWLTRGGSLTAHLARLGRVTVRVTREAVATPWADERGALACAPRAPVWVREVVLAVDGTPFVAAHSIAPLAASKGVWQAMRRLRTRPLAELLYSDPEVTRSALVSRRVIAGHPLFALASHALSPGHATPHAFAARRSVFERRGTPLMVTECMLPALWRHLDAHGERRARDFEGA
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.