PharMolix/UniProtQA huggingface dataset:
Protein: ATG4_COCIM
Sequence: MNTVDIGQKYKRIVEYLWDPEPKNDDDIIEPVWCLGKEYKTSIPRDSEGAEAPESCNMPGMPFLSPMNQMSLSSRDTQAALSKPATPPHQLGIQRSKSREWPTSFLDDFESKFWFTYRSNFPAIPKSRDPDTPLALTLSVRLRSQFLDTHGFTADTGWGCMIRSGQSLLANALSILNLGRDWRRGSKIKEECELLSLFADNPQAPFSIHRFVDYGASACGKHPGEWFGPSATARCIEALSNECKHTDLNVYVMSDGSDVHEDQFRQIAGPDGIRPTLILLGVRLGIESVTPVYWEALRAIIRYPQSVGIAGGRPSSSLYFIGVQGPYFFYLDPHHTRPAVSWNPDSTLSPENLDTYHTRRLRRLHIREMDPSMLIGFLIKDDDDWKDWKRRLRSVTGNPIIHIFDLERPNFGRHLEREEAVDEVEALDDDSN
What is the function of this protein?
Cysteine protease that plays a key role in cytoplasm to vacuole transport (Cvt) and autophagy by mediating both proteolytic activation and delipidation of ATG8.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  The protease activity is required for proteolytic activation of ATG8: cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine.  ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.  In addition to the protease activity, also catalyzes deconjugation of PE-conjugated forms of ATG8 during macroautophagy: ATG8 delipidation is required to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components.  ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS.
What are the official names of this protein?
Probable cysteine protease ATG4, Autophagy-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Preautophagosomal structure.
Protein: EFG_SYNP6
Sequence: MARSVPLEKVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGNAVTDWMEQERERGITITAAAISTSWKDYRVNIIDTPGHVDFTIEVERSMRVLDGVVAVFCSVGGVQPQSETVWRQADRYSVPRIVFVNKMDRTGADFFKVYGQIRDRVRANAVPIQIPIGAESDFQGIVDLVEMKAHIYTNDLGTDILVTDIPAELQETAAEWRSKMVEAVAETDEALLDKYFEDGDLSIEDIKAGLRKGVLIQGNDRLVPMLCGSAFKNKGVQLLLDAVVELLPSPQDIPPIQGTLPDGEVALRPSSDEAPFSALAFKIMADPYGRLTFVRVYSGILQKGSYVYNATKGKKERVSRLIILKADDRIEVDELRAGDLGAVLGLKDTFTGDTLCDDQNPIILESLFIPEPVISVAVEPKTKNDMEKLSKALQALSEEDPTFRVSVDSETNQTVIAGMGELHLEILVDRMLREYKVEANIGAPQVAYRETVRKAVKAEGKFVRQSGGKGQYGHVVIELEPAEPGTGFEFVSKIVGGTVPKEYVGPAEQGMKETCESGVLAGYPLIDIKATLVDGSYHDVDSSEMAFKIAGSMAIKEAVRKADPVLLEPVMKVEVEVPEDFLGSVMGNLISRRGQIEGQATTNGTATVSAKVPLAEMFGYATDLRSMTQGRGIFTMEFSQYEEVPRNVAETIIAKNKGNA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCAF_HHV11
Sequence: MAADAPGDRMEEPLPDRAVPIYVAGFLALYDSGDSGELALDPDTVRAALPPDNPLPINVDHRAGCEVGRVLAVVDDPRGPFFVGLIACVQLERVLETAASAAIFERRGPPLSREERLLYLITNYLPSVSLATKRLGGEAHPDRTLFAHVALCAIGRRLGTIVTYDTGLDAAIAPFRHLSPASREGARRLAAEAELALSGRTWAPGVEALTHTLLSTAVNNMMLRDRWSLVAERRRQAGIAGHTYLQASEKFKMWGAEPVSAPARGYKNGAPESTDIPPGSIAAAPQGDRCPIVRQRGVALSPVLPPMNPVPTSGTPAPAPPGDGSYLWIPASHYNQLVAGHAAPQPQPHSAFGFPAAAGSVAYGPHGAGLSQHYPPHVAHQYPGVLFSGPSPLEAQIAALVGAIAADRQAGGQPAAGDPGVRGSGKRRRYEAGPSESYCDQDEPDADYPYYPGEARGAPRGVDSRRAARHSPGTNETITALMGAVTSLQQELAHMRARTSAPYGMYTPVAHYRPQVGEPEPTTTHPALCPPEAVYRPPPHSAPYGPPQGPASHAPTPPYAPAACPPGPPPPPCPSTQTRAPLPTEPAFPPAATGSQPEASNAEAGALVNASSAAHVDVDTARAADLFVSQMMGAR
What is the function of this protein?
Plays a major role in capsid assembly.  Acts as a scaffold protein by binding major capsid protein.  Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid.  Cleaved by assemblin after capsid completion.  The cleavages products are evicted from the capsid before or during DNA packaging.
What are the official names of this protein?
Capsid scaffolding protein, Capsid protein P40, Protease precursor, pPR, Virion structural protein UL26.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae capsid scaffolding protein family.
What are the subcellular locations of this protein?
[Capsid scaffolding protein]: Host cytoplasm. SUBCELLULAR LOCATION: [Assemblin]: Host nucleus. SUBCELLULAR LOCATION: [Assembly protein]: Host nucleus.
Protein: PTH_FRATW
Sequence: MPKIKMIVGLGNIGKEYQDTRHNVGEWFIAKIAQDNNQSFSSNPKLNCNLAKVSIDYNNVVLVFPTTYMNNSGLAVSKVANFYKIAPAEILVVHDELDIDSGEIRLKKGGGHGGHNGLRSINQHLGTNDYLRLRIGIGHPGHKSKVANYVLSNPSIAQKKDIDSAIDNGICFLDDIINYKLEPVMQKLHTK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_PROPA
Sequence: MAPNLRKSHPLLKMINNSLIDLPTPPNISAWWNFGSLLGICLMTQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLTLVHLTFLHESGSNNPLGIVSNCDKIPFHPYFTLKDILGFTLMLLPLTTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLAPFLHKAKQRTMTFRPLSQLLFWILVANLFILTWVGSQPVEHPFIIIGQLASFTYFTILLILFPIIGALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ACPS_BUCAP
Sequence: MSIIGIGTDIIEIFRIKNIVYNFKDKLAERILSVQELEKYKVNKNPIKFLAKRFAVKEAASKALGTGISYGIKFNQIELYNNNLGKPKLRFLKYALQKSEEMKCKSIFVSISDEKLYACALVILEK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y166_ABVP
Sequence: MAEIGEFLKKYAGFCGLLPPSVDNSLLDFLANLPIILVFLITMPVRFFICIFAGLAKVNPICVLINLLPPLAIAIPFVTAQTPPVCSTQCQYCQSGKGECLNYNPTIAKYFTQCEKQLSVLNKIFCLVGIIIADVLNPILAFINPLIYLAIHKVICLNTNPCICGL
What are the official names of this protein?
Putative transmembrane protein ORF166.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: NRDJ_STRCT
Sequence: MHLDNSSCNLASLNLMKFLRDDTASDGASGAGGNMSLDAERFAKVVELVITAMDISICFADFPTEKIGETTRAFRQLGIGYANLGALLMATGHAYDSDGGRALAGAITSLMTGTSYRRSAELAAVVGPYEGYARNADAHKRVMRQHADANTAAQRMDDLDTPVWAAATEAWQDVLRLGEQNRFRNAQASVLAPTGTIGLMMDCDTTGVEPDLALVKFKKLVGGGSMQIVNNTVPKALKRLGYQPEQVEAVVAHIAEHGNVIDAPGLKPEHYEVFDCAMGERAISPMGHVRMMAAAQPFLSGAISKTVNMPESATVEEIEEIYYEGWKLGLKALAIYRDNCKVGQPLSAKKKEEAKTEAPAEVEKVVEYRPVRKRLPKGRPGITTSFTVGGAEGYMTANSYPDDGLGEVFLKMSKQGSTLAGMMDAFSIAVSVGLQYGVPLETYVSKFTNMRFEPAGLTDDPDVRMAQSIVDYIFRRLALDFLPFETRSALGIHSAEERQRHLDTGSYEPAEDELDVEGLAQSAPRQAGPAKAATTAPAAKAQEPAAAPSPKQAHNSTELLEIQQGLNADAPLCFSCGTKMRRAGSCYVCEGCGSTSGCS
What is the function of this protein?
Catalyzes the reduction of ribonucleotides to deoxyribonucleotides.  May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen (By similarity).
What are the official names of this protein?
Vitamin B12-dependent ribonucleotide reductase, Ribonucleoside-diphosphate reductase NrdJ.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase class-2 family.
Protein: RL9_SHESA
Sequence: MNVILLDKIANLGNLGDQVAVKAGYARNYLLPQGKAVVANESNVKVFEARRAELEAKLAADLAAANQRAEKIAALEAVVIASKAGDEGKLFGSVGTRDIADAVTAAGVELAKAEVRLPLGALRTTGDFEVEVQLHTEVKAVVKVSVVAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PPK6_PSEFO
Sequence: SDPEAPGIWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-6, Psefo-PK-6, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL23_PARXL
Sequence: MSEIRKNDHRLMQVLLAPVISEKATLVADKNEQVVFEVAPDATKQEVKAAVELLFKVEVNSVNVLVSKGKAKRFGRFMGKRKDVKKAYVCLKPGQEINFEAEAK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CAOP2_OPICA
Sequence: MKPSLIIVTFIVVFMTISCVAADDEQETWIEKRGDCLPHLKRCKENNDCCSKKCKRRGANPEKRCR
What is the function of this protein?
This toxin stabilizes ryanodine receptor 1 (RyR1) opening in a long-lasting subconductance state (40% of the full conductance state) (PubMed:27114612).  Furthermore, it triggers calcium release from sarcoplasmic vesicles (64. 2 nM are enough to induce a sharp release, and 50% of the total calcium is released after toxin (100 nM) addition) probably by acting as a cell-penetrating peptide (CPP) (PubMed:27114612).  In addition, it has been shown to dose-dependently stimulate ryanodine binding to RyR1 (EC(50)=3. 2 nM) (PubMed:27114612).  It also augments the bell-shaped calcium-[3H]ryanodine binding curve that is maximal at about 10 uM calcium concentration (PubMed:27114612).  It binds a different site as ryanodine (By similarity).  It acts synergistically with caffeine (By similarity).  In vivo, intracerebroventricular injection into mice induces neurotoxic symptoms, followed by death (By similarity).
What are the official names of this protein?
Opicalcin-2, OpCa2, Opicalcine-2.
What is the protein family that this protein belongs to?
Belongs to the scorpion calcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CDK16_HUMAN
Sequence: MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDTEF
What is the function of this protein?
Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis.  Regulates GH1 release by brain neurons.  Phosphorylates NSF, and thereby regulates NSF oligomerization.  Required for normal spermatogenesis.  Regulates neuron differentiation and dendrite development (By similarity).  Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels.  Can phosphorylate CCNY at 'Ser-336' (in vitro).
What are the official names of this protein?
Cyclin-dependent kinase 16, Cell division protein kinase 16, PCTAIRE-motif protein kinase 1, Serine/threonine-protein kinase PCTAIRE-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Synapse, synaptosome. Note=Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY.
Protein: EFP_BACHK
Sequence: MISVNDFRTGLTIAVDNGLWQVLDFQHVKPGKGAAFVRSKLRNLRTGSVQEKTFRAGEKVEKAHIENRRMQYLYASGEAHVFMDNGTYEQIELGEKQIERELKFLKENMEVSIMTYQGEVLGVELPNTVELQVTETEPGIKGDTASNVTKPATLETGLVVQVPIFINEGEMLIINTGEGKYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCN4B_BOVIN
Sequence: MPGARDQGAARARWLGIGLLGLFLLPVSLSLEVSVGKATTIYAVNGTEILLPCTFSSCFGFENLHFWWSYNSSDTYKILIDGTVKNEKSDPKVKLKDDDRITLEGSTKEKMNNISISLKNLEFSDTGKYTCHVKNPKENDFQHQATIFLQVVDKLEEVDNTVTLIILGVVGGVIGLLIFILLVKKFIAFIIKKTQEKKKECLVSSSGNDNTENGLPGSKAEEKAPTKV
What is the function of this protein?
Modulates channel gating kinetics.  Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation.  Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom (By similarity).
What are the official names of this protein?
Sodium channel subunit beta-4.
What is the protein family that this protein belongs to?
Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: Y672_KLEP3
Sequence: MKRTKKINHSSFRKSWSARHLTPVALAVTAVFMLAGCEKSDETVSLYQNADDCSAANPGKAAECTTAYTNAVKEAERTAPKYATREDCVAEFGEGQCQQTPAQAGVAPENQAQAQSSGSFWMPLMAGYMMGRLMGGGMAQQQPLFSSKNPASPAYGQYTDASGKSYGAAQPGRTMNVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSAAGSTSSSRSMGG
What are the official names of this protein?
UPF0441 protein KPK_0672.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: HAS1_YARLI
Sequence: MGLTKKEKVEKKARSVVKGKADKKAKVEKPSSKPAKSAKPSKSKDEVDELDDEFDEVEGLLEKGDVEEEDEEETNGNEDSEMSDDDEKDVEIEEEDDGEGSDLEEEESTAVVTTAPADAEVVHIASDAERKPFSTIPLSENTMQSLKDMGFETMTPVQEKTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEMLRKLKFKPRNGTGVIVVSPTRELALQIYGVARDLMANHSQTLGIVIGGNNRRQEEEKLNKGVNLLVCTPGRLLDHLQNSQGFVFKNLKALIIDEADRILEIGFEQEMKEIIKILPKERQSMLFSATQTTKVEDLARISLKKGPLYLNVDEHNVSSTAEGLEQGYVVCDSDKRFLLLFSFLKRNAGKKIIVFLSSCNSVKFYGELLNYIDLPVLDLHGKQKQQKRTNTFFEFINAKQGVLICTDVAARGLDIPKVDWIIQFDPPDDPRDYIHRVGRTARGSASGKSIMFLTPSELGFLRYLKAAKVPLNEYEFPNKKIANVQSQLEKLISSNYWLNTSAKDGYRAYLQAYASHHLKTVYQIDKLDLVKVAKSFGFNVPPKVNISIGASGKGAKSIKGKDNHKKRGGPGGKKFTR
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase HAS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MIAB_CORGL
Sequence: MNHAKVNQHPGQATLPETAEGQVRTYEVKTYGCQMNVHDSERLSGLLEEAGYVAAPEDTTPDLVVFNTCAVRENADMRLYGTLGNLRSVKEKNPGMQIAVGGCLAQKDKDTVVKKAPWVDVVFGTHNIGSLPTLLQRAEHNAQAEVEIVDSLEQFPSVLSAKRESAYAGWVSVSVGCNNTCTFCIVPSLRGKEQDRRPGDILAEVQALVDQGVTEVTLLGQNVNAYGVNFVDPELERDRSAFSKLLRACGEIEGLERVRFTSPHPAEFTSDVIDAMAETPNICPQLHMPLQSGSDKVLKEMRRSYRSKKFLSILDEVRAKIPHASITTDIIVGFPGETEEDFQATLDVVKKARFTSAYTFQYSPRPGTPAAEYENQLPKEVVQERYERLMVVQEQVCEEENQKLIGTTVELLVQAGGGRKNDATKRMSGRARDGRLVHFAPEGDIDGEIRPGDFVTVTVTEAKPFFLIADSGVQTHRRTKAGDNSAVGQVPTTAPIGVGLGLPQIGAPKVAPATESACCSIN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C14B3_MAIZE
Sequence: MEVAMAMAVKVLLSLCCVGACGLAVYLYHILWLVPQKVLAKFEDQKIGGPRPSFPYGNLADMREAAAAAKAARASARRSGSGGGGIVHDYRPAVLPYYEKWRKEYGPIFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGGGILKSNGEAWLHQRKIIAPEFFLDKVKGMVDLMVDSAQPLLMSWEERVDRNGGITDIKIDDDIRAYSADVISRTCFGSSYIKGKEIFMKIRELQQAVSKPNVLAEMTGLRFFPSMRNKQAWELHKQVRKLILEIVKESGEDRNLLSAILHSASTSRVGIAEAENFIVDNCKSIYFAGHESTAVTAAWCLMLLGLHPEWQNRVREEVHEVCRGQPVDSRSLQKMKNLTMVIQETLRLYPAGAFVSRQALQELKLGGVHIPKGVNIYIPVSTMHLDPELWGPDVKEFNPERFSDVRPQLHSYLPFGAGARTCLGQGFAMAELKILISLIVSKFVLKLSPHYQHSPTLKLIVEPELGVDLTLTKVQSVCTKRGTAI
What is the function of this protein?
May be involved in gibberellin metabolism.
What are the official names of this protein?
Cytochrome P450 714B3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein.
Protein: VKT27_CYRSC
Sequence: MGIARILSAVLFLSVLFVVTFPALLSADHHDGRIDTCRLPSDRGRCKASFECWYFNGRTCAKFIYGGCGGNGNKFPTQEACMKRCAKA
What is the function of this protein?
Toxin with inhibitory activity on serine proteases, but not on potassium channels (PubMed:24418069).  Is active against trypsin (Ki=0. 281 nM), kallikrein (Ki=337 nM), and chymotrypsin (PubMed:24418069).
What are the official names of this protein?
Kunitz-type kappaPI-theraphotoxin-Hs1c, kappaPI-TRTX-Hs1c, Huwentoxin HW11c27, Kunitz-type serine protease inhibitor HWTX-XI-IS27.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 02 (native) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TALB_DICDI
Sequence: MSLTLKIQIVRDKQVKAMKFSPTQTVAEVCAQVREKINETSGDDHGLFQPGIDAKRPSRWLKMDKTLQFYDLKINDELDYKKKHRPLKVRLMDETVKTMLVDDSLTAGEILEIIGKRIGIKNYEEFSLQTEGAAAGEWINHAQPLHEQGVPDDAVVLLKKKFFVDDFNVNRDDPIQLHLVYVQSRDAIISGSHPCSYEEAVQFGALQCQIQLGNHNPNLHKPGYLKIKEYFPPSFHKKKDAEKDIYKEFRKLTGMSESNSKFRYVQLCRSLKTYGITFFLTKERVKGQKKPVPKLLGITRDSILRLDAETKEVEHEYPLNHLRRWAASPQSFTLDFGDYEDDYVSVITTEGEAISQLLSGYIEILMKKRKDTGTVIDENETDIANVESVGRIRGQTSQATTSSSLSGYDGNGGREGQYSAPGQAIGYRGGLGGPLSIKVTNIDSASAAVANLLNEMELDPNAVIGQKSSLTPQQWRQQLAIHAKAVAAAAGKLLGNLNNPNGMDKNQMDSNARDVALTIDQLVHAARAASIASGEDPDGEMPLFDGAKAVAESISKLLKATKDLSSNPNDENARNLIAQAADQLKLMTSYLDGACNGVITDSGTLRLLMEAGKAIAIATQDLVNQANVAIQDINDPIRKNQLNMAIDETMKAGIHASAVSQALAATILDPNCRQQFNTAAKTAQDTNNYLLSAAKAAQMDPALLEKLRASAKSIAEAYASLIQSADLAQPKSGDDVEFTSASKTILSAAAQLLGSQGKSDNIMQQAKVIEEAMGHLIAGARRAALKTDDPGVRDRLIQCSKAVAEAVRNLMEIAQDSADNPEDKVLFAKLQESSKRVATAVKQLVGDAGKESAFQLLRTNAKLACAATTGLMNTSRQSMLQGHLSDQESNKLLLACVQAGPAITNLLNSITSSQKAPNDLPAQNQLIEVARVSAPIAYQVVAVAKGAIPHFTDQHSKQEVSNSSNTASDAIRALLDAIGDLTSAVGQQEFDDALDTVQALEADMESSTMLVQAGTTHQIPGQTRENALELLNVAARALGSSAKQVLLQYKTSPEKLGETSKDLATSVSQVTNAAKSVCFTTQNRSVQKAVLGAAKQITTESTNLVSCARAVSSNPGDPSLESALQSSVKAIAEALANLLTTSKGGDPGGKDLDDAIEAIKNDTKRINNPPVNLGGEGGVNSEKAISSSKALVGAVSQVAANARSNPSALGASARTTSTTFTLLVDTINLCTGTIVNKQLAIEIVKGGQLLGIETIKLLQASRFAASRPGEGEGELNQTQQSVSNTVKQLIYNIQSSVPGQAEIADALEIVKQAIIALNSSESSGSRPNALESLTQAAKNLADYTAQVVQSKGNSEKMGTQCKSASESLKDVVEYTKASLSTAEGHPDSIKTLASKVDDSSNALFNSCKKTGQLSDQDKKNAALDAKNLALSVPNLMGAAKKISASLVQSNPEKSKDILLVAQNITIATSKLVNIAKSVASGQSQADVSQLAATKKEVSELISKLLNATNGHDQDATTISIDLDSLSKSEQALLDASRSTANYMSQFMAIGKTISTGTKDPNVHQQFSGAAQNVSSGVQQLLSAINGMKPEQKDLDESIEIIQNAVVDLDSATLNAAIGLLENTAPVGKTAQVCQEELVDISRELATSMKTFLAAPKQDPTNLGQSAKDTANILPKIVNISKQLASLTTNPDIKQTQLLLSKKLADNMLELMISAKSGDVSDSKQAFNASQSIADILTSVKGGVMQSRDCDESIQIIGKSKENLQKPANDTHGKTYQQYRDEMTEIAKQLALGVSQLANSAKSKPEEIGSSSLKIASIIPRLAETARSTAAATNDVAAKKKLIDSTTGIIDATSNIISDAKLASADHKNTQLQQKISNNFKDITTQIANLIAALRAGATADRDIENACNEVNHVTTDLDAASLFAAAGQIDIDTDGHTTQNIQEQVGKLAQDLKDSKNQLAEASGKTIEDVGTSAKATASINQKLAHATKVCAALTSDSTTQQNLLSAARTVSSNLQQTISASKNAQKNPNAGNKAILDKSSQELEESIDSLANLVQSSTTTKGISELEGVSSEIRKQLAAYDSATANVNANATAEDVVNSAKNLAESIAYLVSSCNNSPEDIAEASKGTTLAIKSLLANAKGASVLTDDAVIQQNVTESAKAAAQTVLKLIQAAKQQRNDPSNPAHQNKLSEISSEVVESISTCVNAAEDLPEGKRAKLLFAAGESLEETAEKELKAAAAIIEEATAALLNAKKKREQNRIASGIDEAGIDESILEAARAITSATGVLVQCATNVQHELVLAGKVGNKGNMYRRDPTWARGLISAAQAVAGSVQGLVHSANSSSQGKVDEEQLVASAKGVAAATARLVTASRAKADLNSASNSQLAQAAKQVSNATAALVEAAKQVNEEPEVEFDTTNLSNAQIISKEMDQQIQILKLKKELEQAEKKLFSIRKKEYSDQTGNPSPAKDSDNKPTTSISVGITPTKRTTQASPPSPPLTPTQQAAGTPTLPPRPLMKKPAPSQAPSSPVAPVSAPVSKPSPKPAPKPAAPTAAAPNKTYTLEELKKKPANIDHSNLEIYLSDEEFKAVFNCERSELAAMPTWKRNNIKTKLGLF
What is the function of this protein?
Actin-binding protein required for multicellular morphogenesis.  Substrate of pkgB and/or pkbA.
What are the official names of this protein?
Talin-B.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Protein: GUAA_SALDC
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVLTDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MURD_RHOPA
Sequence: MIPVTSFAGQSVAVFGLGGSGLASCHALKAGGAEVIACDDNLDRMVEAAQAGFITADLRNLPWTNFAALVLTPGVPLTHPAPHWTVLKAQEAGVEVIGDVELFCRERKAHAPRAPFVAITGTNGKSTTTALIAHLLREAGWDTQLGGNIGTAILSLEPPKDGRVHVIEMSSYQIDLTPSLDPTVGILLNVTEDHIDRHGTIEHYAAVKERLVAGVQDGGTSIIGVDDEFGRAAADRIERAGKRVVRMSVQGPVTFGITADLDSIRRVDGGTSTEVAKLGGIGSLRGLHNAQNAAAAAAAVLALGVSPEVLQQGLRSFPGLAHRMEQVGRQVGEQGTTLFVNDSKATNADAAAKALASFGDIFWIAGGKPKTGGIESLAEYFPRIRKAYLIGQAAQEFAATLEGRVPYEISETLEAAVPAAARDAAASGLAEPVVLLSPACASFDQFRNFELRGTRFRELVTALDGVAAV
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.