PharMolix/UniProtQA huggingface dataset:
Protein: K2C80_BOVIN
Sequence: MACRSCVVGFSSLSSCEVTPAGSPRPATAGWSSCGPPEPGLSSHSLTGCWTAGTVSKVTVNPSLLVPLDLKVDPAIQQQKNNEKEEMKVLNDKFASLIGKVQALEQRNQLLETRWHFLQSQDSATFDLGHLYEEYQGRLQEELRKVSKERGQLEANLLQVLEKVEDFRIRYEDEISKRTDMEFTFVQLKKDLDAECLRRTELETKLKGLQSFVELMKSIYEQELKDLAAQLKDVSVTVGMDSRCHIDLSGIVEEVKAQYDAVAARSLEEAEAYSRSQLEERAACSAEFENSLQSSRSEIADLNVRIQKLRSQILSIKSHCLKLEENIKVAEEQGELAFQDAKAKLAQLEDALQQAKKDMARQLREYQELMNTKLALDIEIATYRKLMEGEESRMDMPSATVVSAVQARCRTAPTLPHPLCSL
What are the official names of this protein?
Keratin, type II cytoskeletal 80, Cytokeratin-80, CK-80, Keratin-80, K80, Type-II keratin Kb20.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: LGT1_BACC1
Sequence: MLLGSVPQLDRVAIQLGPFPVYWYGIIIGTGVLLGLWLATREGERLGIPKDTFVDLVLIAVPIAILFARMYYVIFEWEYYAQNPSQIINIRQGGLAIHGGLIGAVITGILFAKRRGVSFWKLADIAAPSILLGQAIGRWGNFMNQEAHGDEVTRQFLEGLHLPDFIINQMYIDGVYYHPTFLYESLWNFAGVILLLALRKVNLRRGELFFTYLIWYSIGRFFVEGLRTDSLMLGPLRIAQVMSIGLVVISVIFIIVRRKMGQADKRYLEN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RCO1_BOTFB
Sequence: MAILNDPPSSTTILSLHTPDVPPPSKPTPATTSHPQDSRNPRNLTSKWPTAIDLAGSSLPCRLEGEVANLVVLGSIPPEINGTFYRVMCDPFVPPHPQNVPIDGDGNISAFRFHNGIVDMKMQYIETERYKLERQANKALFGLYRNPYTHHPCVRAAVDSTANTNLVMWADKLLALKEVGLPYEVDGDTLETLGYDPFASEGVESKTFTAHPKVDPFTDELVVFGYEAKGLATLDVVTYTLDAQGKKVEELWVKSPWCAFIHDCAITENWLILVCWCFEANIERMKKGGQHWAWDYEKPATFIVVPRRKSTPLPDGWKEGESRYYEWNNCMPVHTAGAWEGKDGKLYMESSRVHDNAFPFFPPDDGRMPNPDTKGDFARWEFDLSQPSGSKIQDPLVVLDIPCEFPRIDERFMTKEYEWVFLDVFIPEQGDGKSNIYQGLNGLAMHNNKTNETKYFYAGQDSHVQEPIFIPRSKDSKEGDGWVMAMVERRIANRCDLVVIDTRDFEKAIAIVELPFHIKAQIHGNWVGATETRGTKSLVREMEKIEISGKGALEPMA
What is the function of this protein?
Dioxygenase that cleaves the interphenyl C-alpha-C-beta double bond of resveratrol to yield 3,5-dihydroxybenzaldehyde and 4-hydroxybenzaldehyde (PubMed:21073977).  Cleaves also piceatannol, a compound that differs from resveratrol only in the occurrence of an additional hydroxyl group, which leads to the production of 3,4-dihydroxybenzaldehyde and 3,5-hydroxybenzaldehyde (By similarity).
What are the official names of this protein?
Resveratrol cleavage oxygenase 1, RCO 1.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
Protein: RPP29_BOVIN
Sequence: MTSVVYHAFSQKEAKELDVQHSGAQRAEAFVRAFLKRSMPRMSQQALEDHLQRKAVVLEYFTHRKQKEKRKKSKGLSAKQRRELRLFDIKPEQQRYSLFLPLHELWKQYIRDLCNGLKPDTQPQMIQAKLLKADLHGAIVSVTKSKCPSYVGVTGILLQETKHVFKIITKEDRLKVIPKLNCVFTVEIDGFISYIYGSKFQLRSSERSAKKFKAKGTIDL
What is the function of this protein?
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein subunit p29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PRVB_ESOLU
Sequence: SFAGLKDADVAAALAACSAADSFKHKEFFAKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLADGDKDGDGMIGVDEFAAMIKA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions.
What are the official names of this protein?
Parvalbumin beta, Parvalbumin II, Parvalbumin pI 4.10, Parvalbumin-2.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: RPOA_SHEVD
Sequence: MQGSVTEFLRPRLVDIEQVNPTRAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSKEGVQEDILEILLNLKGLAVVIEGKDEAMLTLSKSGAGPVTAADITHDGDVTIMNPEHVVCHLTGNNEISMRIRVERGRGYVPASARAQTEDDDRPIGRLLVDASFSPVARIAYNVEAARVEQRTDLDKLVIDMTTNGTLDPEEAIRRAATILAEQLDAFVELRDVTEPEQKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASLVDDL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: IF3_MYXXD
Sequence: MIREQRSSRGGSRDQRTNRRIRAREVRVVGSDGSQLGVMPLEAALDRARTEGLDLVEISPMASPPVCKIMDYGKFKYEEKKKASEAKRAQVTVLLKEVKLRPKTEEHDYEFKVRNTRRFIEDGNKAKVVIQFRGREITHREQGTAILDDVAKDLKDVAVVEQMPRMEGRLMFMILAPTPKVAQKARELVRQAATAAKRPPPPGAPGAGKSAAGASSGAEEKAEETAEEKKEAQAAPAAAEAQSPTAS
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R111A_XENLA
Sequence: VEMIASKVSNEFNHLCSDTNKQQSDLNSNGTEQDKSLVVHKKRKSQQAGTSYAQSCEVKEYQRLLRLQPKSDEDNDSSFSDCISSPSSSSHFGDSDTMTSDEDKDNPLSSVNSTPRTQSARAQKWPRPHTDSVSSLLMKRPCYQVSSLRRPLHRKRFVKNVSSQRTQKQKERIMLQRKKREVLARQKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSPGENHQDGTTLPSGGMDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGETYRSRATLGHPRSHWGQNSQSGRTQEQRTRNRVSTIIQPLRQNTTEVVDLTVDEDDPTVVPTTSGRVESQPVSIVSSLTSTSEPASDSMSGLMGSAVPEIPAIPPNTVGTIADDSRTCTSGANADGGPPAMPRLPSCCPQHSPCGGSSQNHVLGHPHSSCFPPHSHHFPHHHHHHHHSSHPGVPLSPSFRDSHCTVERNAAVPPPCGVSSSSGSTYHDPQALPVDLSNNGIRSHGSVGFHSTSAFDPCCPGSSSRSTVYGHQATTSTAQTMAIDGYGSSMVAQAQPPPPLSSCRHYMHASYTSLPRPLHHQTSSCPHSNSASQPPPPPPPPPPPPMDYVIAHQVPFISPLPSLTSTHAVPPPPPSHHLSAAAAPLPQHLSTSHQSMSHHISATAPATQRLHAHEVIQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQGPERSAWEIAIETGVTAAPYQTGPLHTHLAPYHPPPRLHHLQIGALPLMVPDMAGYPHIRYISSGLDGRSFRVPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKKVSTDWFSQRKLHSKQDGEEAPEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIDTQLPTES
What is the function of this protein?
E3 ubiquitin-protein ligase required for mesoderm patterning during embryonic development by enhancing signaling of the subset of TGF-beta factors responsible for the formation of dorso-anterior tissues of Spemann's organizer (PubMed:11298453).  Acts as an enhancer of the transcriptional responses of the smad2/smad3 effectors, which are activated downstream of BMP (By similarity).  Acts by mediating ubiquitination and degradation of SMAD inhibitors such as smad7, inducing their proteasomal degradation and thereby enhancing the transcriptional activity of TGF-beta and BMP (By similarity).  Specifically binds polysumoylated chains via SUMO interaction motifs (SIMs) and mediates ubiquitination of sumoylated substrates (By similarity).  The regulation of the BMP-SMAD signaling is however independent of sumoylation and is not dependent of SUMO interaction motifs (SIMs) (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase arkadia-A, RING finger protein 111-A, RING-type E3 ubiquitin transferase arkadia-A.
What is the protein family that this protein belongs to?
Belongs to the Arkadia family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, PML body. Note=Upon TGF-beta treatment, translocates from nucleus to cytosol.
Protein: G3PC_ANTMA
Sequence: MAPIKIGINGFGRIGRLVARVALQRDDVELVAVNDPFISTDYMTYMFKYDSVHGAWKHHELKVKDEKTLLFGEKPVVVFGRRNPEEIPRASTGAEYIVESTGVFTDKDKAAAHLKGGAKKVIISAPSKDAPMFVVGVNEKEYKSDLHIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSAKDWRGGRAASFNIIPSSTGAAKAVGKVLPQLNGKLTGMSFRVPTVDVSVVDLTVRLEKKATYEQIKAAIKEESEGKLKGILGYTEDDVVSTDFVGDSRSSIFDAKAGIALNDNFVKLVSWYDNEWGYSTRVVDLIVHMASVQ
What is the function of this protein?
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.  Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_EXIS2
Sequence: MRVVLQRVKEASVTVEGTVAGQIDQGFLLLVGVTHDDTLEQVNWLADKIAGLRVFEDEEERMNRSLQDVEGKILSVSQFTLYGDVKKGRRPAFTEAAKPDVANELYEAFNARLRQQGIIVETGQFGAMMDVALVNDGPVTLILEK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGPS1_PONAB
Sequence: MAVAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNRDRQRRRSPWLLLAPLLSPAVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAESFELMKGQIRVAKRRVVMASLYLGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLPQRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVQVVDGMVHPYKGDRTEYCKAANKRVMDVINSARTRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVVGAIPAAYVHIERQFYSEVCSLGQQERVQLQEYWRRGWTFHAKGLWLYLAGSSLPCLTLIGSPNFGYRSVHRDLEAQIAIVTENEALQQQLHQEQEQLYLRSGVVSSATFEQPSRQVKLWVKMVTPLIKNFF
What is the function of this protein?
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial, Phosphatidylglycerophosphate synthase 1, PGP synthase 1.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MED11_ARATH
Sequence: MDPQTQNTSLQRLQNVENRVVKVLELAGGVMEELASPSGPKKEFVNSHCREFMQSMKDIQVTLREEIKSACEYRPFEKCDYNARIANEICFQKLEYVLTQLEDLKQTADRYPSSD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 11.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM3_ORYSJ
Sequence: MPPPPRCAATTAHHSLLGSPTCLARPRRRCCPVRAAVAVQAEAQAKVSLIRIGTRGSPLALAQAHETRDKLKAAHSELAEEGAVEIVIIKTTGDMILDKPLADIGGKGLFTKEIDDALLQGRIDIAVHSMKDVPTYLPEGTILPCNLPREDVRDAFICLTASSLAELPAGSVVGSASLRRQSQILYKYPSLKVVNFRGNVQTRLRKLKEGDVHATLLALAGLKRLNMAETATSVLSVDEMLPAVAQGAIGIACRSSDDTMMNYLSSLNHEDTRLAVACEREFLSVLDGNCRTPIAAYASRDKDGNCSFRGLLASPDGSTVYETSRTGPYDFDIMVEMGKDAGHELKAKAGPGFFDSLQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, chloroplastic, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RIMP_PSEPW
Sequence: MGASPIFYLHSMHEGVQVSSKLEQLQALLAPVVEGLGYQCWGIEYVSQGKHSVLRIYIDKEGGILVEDCEAVSRQASAILDVEDPISSEYTLEVSSPGMDRPLFTLEQFASHAGEQVKIKLRTPFEGRRNFQGLLRGVEEQDVVVQVDSHEFLLPIDSIDKANIIPSFD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_GLUDA
Sequence: MPTINQLIAKGREPAAKRNKVPALQGCPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGYEVVSYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHILRGVLDTQGIAKRRQRRSLYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RECO_MARSD
Sequence: MELTEKVVILKTGKFKENDLWVRFLSATRGVQNAFAFGGSRSRRRFGGCLEPFSQVLFKTGTNKTGTYQVLQEGSLVKGYPGIRSDFRKMGLAANCFKFIESAVLERDGNRAVFDLLTETLDVIEEADPDDFFPLFFRAKVAFEQGYNPDFTICAQCGKPLFSSRPVVFNIEKGQLNCLDCNDGRQGETISSGTARTLAWIQDTGPASWINLRLPADIRQECFSVMDRFMAYHMGVVWEGNGYRKI
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SOML_SIGGU
Sequence: MLMFTAIQRGVWVALLWPHLLTASMPLDCREENGNLSRCPTISQEKLLDRVIQHAELIYRVSEESCSLFEEMFVPFPLQLQRNQAGFTCITKALAIPSSKSEIQQISDKWLLHSVLMLVQSWIEPLVYLQNTLDRYDGAPDMLLNKTKWVSEKLISLEQGVVVLIKKMLDEGMATTAYNEQSLFQDDAQPDMLESVMRDYTLLSCFKKDAHKMEILLKLLKCRQNDIYSCA
What are the official names of this protein?
Somatolactin, SL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: C76C2_ARATH
Sequence: MDIIFEQALFPLFCFVLSFFIIFFTTTRPRSSRKVVPSPPGPPRLPIIGNIHLVGRNPHHSFADLSKTYGPIMSLKFGSLNTVVVTSPEAAREVLRTYDQILSSRTPTNSIRSINHDKVSVVWLPPSSSRWRLLRKLSATQLFSPQRIEATKTLRENKVKELVSFMSESSEREEAVDISRATFITALNIISNILFSVDLGNYDSNKSGVFQDTVIGVMEAVGNPDAANFFPFLGFLDLQGNRKTLKACSERLFKVFRGFIDAKLAEKSLRDTNSKDVRERDFVDVLLDLTEGDEAELNTNDIVHLLLDLFGAGTDTNSSTVEWAMAELLRNPETMVKAQAEIDCVIGQKGVVEESDISALPYLQAVVKETFRLHPAAPLLVPRKAESDVEVLGFMVPKDTQVFVNVWAIGRDPNVWENSSRFKPERFLGKDIDLRGRDYELTPFGAGRRICPGLPLAVKTVPLMLASLLYSFDWKLPNGVGSEDLDMDETFGLTLHKTNPLHAVPVKKRGRN
What are the official names of this protein?
Cytochrome P450 76C2, Protein YELLOW-LEAF-SPECIFIC GENE 6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VF129_ASFP4
Sequence: MEHPSTNYTLEQQHEKLKNYVLIPKHLWSYIKYGTHVRYYTKQNVFRVGGFVLQNPYEAVVKNEVKTAIRLQNSFNTKAKGHVTWAVSYDDISKLYAKPDAIMLTIQENVEKALHALNQNVLTLASKIR
What is the function of this protein?
Plays a role in the inhibition of type I interferon signaling pathway.  Mechanistically, specifically interacts with 2',3'-cGAMP and cleaves it via its phosphodiesterase activity.  In turn, prevents 2',3'-cGAMP interaction with host ER-resident STING1 leading to inhibition of downstream signaling pathway and type I interferon production.
What are the official names of this protein?
Uncharacterized protein C129R, pC129R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C129R family.
What are the subcellular locations of this protein?
Virion.
Protein: TLCE_RICCN
Sequence: MLSTSSRSFKNKFRAAFWPVHNYELGKFIPMSTLMFCILFNQNVLRILKDSILISEISAEIAGFAKVYCVTPAAALFVIIYAKMINYLTFEKIFYYLSAFFISFFVLFTFVIYPNIHIFHVHPNNLADWMERYPHFKWYISLVGNWGYIVYYSLAELWPNIFYVLLFWQFANELTTTEEAKRFYTLFSLFGNSSLILVGFLMMNLSSEDTIIKKFMSISDSKITLVQVSTTIVAIVAIICCLLVRFISKNVFTNPLFYAKAKSGRSTSERMGLIKSFKYIAKSKYLWLLLICSAAFGFAINLVEAVWKAKIKELYPTVNTYAEFNSLYILWTGVAIMVMTIIGNNIMRMHNWFVAAVISPVIIMVTGILFFVLIVFDQQILSLFDGAILMSPLALAVSIGGIQNILAKGTKYSIWDTSREMLYIPLDEELKTKGKAAVDVISAKVGKSSSGLVQSIIFTLVPTATFTLISPILMVVFTFVCLAWIYAVRKIYCEYQKIA
What is the function of this protein?
Provides the rickettsial cell with host ATP in exchange for rickettsial ADP.  This is an obligate exchange system.  This energy acquiring activity is an important component of rickettsial parasitism (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein 5, ADP/ATP translocase 5.
What is the protein family that this protein belongs to?
Belongs to the ADP/ATP translocase tlc family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMA_PHEZH
Sequence: MSLETLPTLREALEAHGLWAKKAFGQHFLLDLNITRKIARLAQVGDGDVVIEVGPGPGGLTRALLETGARVIAVEKDERFRPLLQEVADAAPHLTLVFGDALTADEAALSAGRPAHLVSNLPYNVGTPLLIKWLTGPWTPASLTLMFQKEVADRITAAPGEDAYGRLAVIAQATADARPVMDVPARAFTPPPKVESAVVRLEPRAARPSPERLDALQKVTAAAFGQRRKMLRSSLKALGGEPLITAAGLDPAARAEVVPVAGFLALADAWLARREAPATAAPRGR
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3749_BRUSU
Sequence: MQNRTLPYFLILPSLLLAAVVIFWPVVHLFEIATHDVNRFGQLREFNDGANFTALFATAEFMNALWRTAVWTVAVVGGALVLSIPVAIILNMDFYGRSVARVIIMLPWAVSLTMTAIVWRWALNGESGMLNSALHGLGLIDTNIQWLASAATAFPMQILVGILVTVPFTTTIFLGGLSSIPDDLYEASSLEGASLWQQFREITFPLLKPFVNIAIVLNTIYVFNSFPIIWVMTQGGPANSTDILVTHLYKLAFRLGKLGEASAVSLIMLAILLVFTVIYIRISTRSEQS
What is the function of this protein?
Probably part of an ABC transporter complex.  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Probable ABC transporter permease protein BRA0749/BS1330_II0742.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYH_MYCPA
Sequence: MPEFSAPKGVPDYVPPDSAQFVAVRSGLLDAARRAGYGDIELPIFEDTALFARGVGESTDVVSKEMYTFADRGDRSVTLRPEGTAGVVRAVIEHGLDRGTLPVKLCYAGPFFRYERPQAGRYRQLQQVGVEAIGVDDPALDAEVIAVADAGFRSLGLDGFRLEITSLGDDSCRPQYRELLQDFLFGLDLDEETRRRARLNPLRVLDDKRPEVRAMTADAPVLLDHLSDAAKQHFDTVLAHLDALGVPYVINPRMVRGLDYYTKTTFEFVHDGLGAQSGIGGGGRYDGLMRQLGGQDLSGIGFGLGVDRTLLALRAEGKSVGSAARCDVFGVPLSDQAKLRLAVLAAGLRAAGVRVDMAYGARGLKGAMRAADRSGARIALVLGDRDIDAGTVGVKDLQTGSQVSVELDSVVAEVLSQLGR
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLW3_SCHPO
Sequence: MFLLQRFFIYGLFLACFYTTVFGEKHFEAEEYRDSFLSQENMNKINHTTIERLFREMTENDPSLLSSSKTLAELSKGELAKAREDLKSVLSFLKNNLPVDTESSSEAFTIEKDNNSCVWLNSVKSFVEKQFSYSSGTNGILATFLTAIPPNIFILLVPKSFDTSMLNLFVAVSAGSLLGDVFLQLLPTVYSTNGGDFPASSVYSILIGALVFFLMDKGIRILIHERPSSLSKPKKDGEETSSVNKPSASSTQTDVKGVEGLRKRNVKDDQNSKGHEPDLIRHVVEEVSEEYNDKTVVYLNLLCDSFHNFMDGLAITSAFFTNTSIGISTTFAVLLHEIPAEIGDLAILLRNGYTKSQVLVLQMITMVTGLLGAIVATYIYTASSSSSPYGSFLLQLEDKLLPFTAGGFLYIAYLGVFPELLEINLSKGKLGNMIYTALYMMFIVGGFSFLYYV
What are the official names of this protein?
Uncharacterized zinc transporter P8A3.03.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MOTB_BPT4
Sequence: MIINIGELARVSDKSRSKAAGKLVEVVSIQLKHGVKDEDSEVKVRIIPKDGKSKPQFGYVRAKFLESAFLKAVPAKGIETIDTSHVGVDFKWKLGQAIKFIAPCEFNFIKDDGRVVYTRAMCGYITDQWVEDGVKLYNVVFLGTYKVIPESWIKHYSNALYA
What is the function of this protein?
Compacts the host nucleoid (PubMed:34365505).  Probably dysregulates hundreds of host genes including derepression of most of the H-NS regulon (PubMed:34365505).  Plays a role in the transcriptional regulation of middle promoters (PubMed:3880747).
What are the official names of this protein?
Transcription regulatory protein motB.
Protein: RL21_SHEPA
Sequence: MYAVFQSGGKQHRVEAGHTVRLEKLEVATGETIEFDQVLLVADGETVHVGAPLVEGGKVVAEVISHGRADKVTIVKFRRRKHHDKKMGHRQWFTEVKITAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: TBC3A_HUMAN
Sequence: MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
What is the function of this protein?
Acts as a GTPase activating protein for RAB5.  Does not act on RAB4 or RAB11.
What are the official names of this protein?
TBC1 domain family member 3, Prostate cancer gene 17 protein, Protein TRE17-alpha, Rab GTPase-activating protein PRC17.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Associated with lipid rafts.