PharMolix/UniProtQA huggingface dataset:
Protein: METK_GEOTN
Sequence: MSAKRRLFTSESVTEGHPDKICDQISDAILDAILEKDPNARVACETSVTTGLVLVSGEITTSTYVDIPRIVRDTVREIGYTRAKFGFDADTCAVLTAIDEQSPDIAMGVDQALEAREGQMTDEEIEAIGAGDQGLMFGFACNETEELMPLPISLAHRLSRRLAEVRKTDVLPYLRPDGKTQVTIEYDENGKPVRVDTIVISTQHHPEIEHDQIERDMKEHVIKPIVPAELLDENTKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAAGLADKCEVQLAYAIGVARPVSISIDTFGTGKVSEDVLIEVVRNNFDLRPAGIIKMLDLRRPIYKQTAAYGHFGRTDVDLPWERTDKAAVLKEQALALAKNE
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_CITK8
Sequence: MMTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTIGITPRGDGEIHLLTPVEGVENDDNLIVRAARLLMKTASAHGRLPAGSGADISIEKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSVDELAETGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFGNDCEVIARKRFREVDAALSWLLEYAPSRLTGTGACVFAEFDTESAARQVLKQAPEWLNAFVAKGVNLSPLQKAML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: EFTU_CLAM3
Sequence: MGKAKFERTKPHVNIGTIGHVDHGKTTLTAAISKVLADKYPSATNVQRDFASIDSAPEERQRGITINISHVEYETPKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMAQTREHVLLAKQVGVPYLLVALNKSDMVDDEEILELVELEVRELLSSQDFDGDNAPVVQVSGLKALEGDEKWVEQIVKLMDAVDESIPEPVRDKDKPFLMPVEDVFTITGRGTVVTGRAERGTLAINSDVEIVGIRPTVKTTVTGIEMFHKQLDEAWAGENCGLLLRGTKREDVERGQVIVKPGSVTPHTDFEGTAYILSKEEGGRHNPFYANYRPQFYFRTTDVTGVITLPEGTEMVMPGDTTDMNVALIQPIAMEEGLGFAIREGGRTVGAGTVTKIVK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_METRJ
Sequence: MSDPDRARVLAAAGVSRETAERLDLYVAQLRRWQPIKNLVGPATLTEVWSRHIDDALQLLDLAPEARTWLDLGSGAGIPGLILAIAGRERGVRVDLVESNARKCAFLTETARLTEAPARVRNARIEAVIGEYGGTDVVCARALAPMTQLLAWTEPLLKTGTTGLFPKGRDVQAELTQAGAQWRVVNDLVPSRTDSEARIVRVTALAAPSHR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT8C_CHICK
Sequence: MRGSTFLLLSIVGIYGAILNAAAWSVNNFLMTGPKAYLTYSSSVAAGAQSGMEECKFQFGWERWNCPESALQLSTHNRLRSATRETSFVHAISSAGVMYTLTRNCSLGDFESCGCDDSRNGRVGGRGWVWGGCSDNVEFGERISKLFVDALETGHDTRALINLHNNEVGRLAVKATMKRACKCHGVSGSCSIQTCWLQLADFREIGNYLKMKYDQAHKLEMDKRRMRAGNSADSRGATAETFHHVHSTELVFLEDSPDYCTRNASLGHHGTEGRECLQTGKNLSQWERRSCRRLSTECGLKVEERRTEVVSSCNCKFHWCCTVRCEQCRQLVAKHFCARRDAAVANHTKRRNKGHRR
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  Is likely to signal over only few cell diameters.  May be involved in the regulation of axis formation and in the rhombomere specification.
What are the official names of this protein?
Protein Wnt-8c, CWnt-8.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: ZRAS1_MOUSE
Sequence: MVERMKKDTGDETKTKVQEEPPSPSPPPPPPPRRERQKQHYWVPEREKKQIERHIHRTSHAREFTDKPWRQPRLFSETTLPKIVLEEESIPQAQKRRQAHERELLQIKDHRERMIRGRELLQQRLKDRILRKSPSQIPLPEKRDQVKKQKKEFEKVVAYPLVQPSCTSRIKVDVLMEKSQDEEDLSTIIKPFGRRFLAVPPFLRTQIGKIKDL
What is the function of this protein?
May be involved in male sterility.
What are the official names of this protein?
Putative uncharacterized protein ZNRD1-AS1, T-complex testis-expressed protein 4, ZNRD1 antisense RNA 1, ZNRD1 antisense gene protein 1.
Protein: CCME_CELJU
Sequence: MHPQRKQRLMIVLFIVVFSSLAVGLIAYALRENINLFYPPSKIAAGDVPHNTRIRAGGCVKPGSVVRSQENLDVRFVITDGNADVVVSYTGILPDLFAEGEAAVINGIVTEAGDIQASEVLAKHDETYMPPEVAEAMKGKGQHQATCGGLNYGA
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RS8_FERNB
Sequence: MWSDPIADMLTRIRNANQVFKEQVDVPASNLKKAIADILVREGFIKGYTYIEDGKQGILRIQMKYKGTRKNRERVIHGIVRVSKPGRRIYVGKNNIPRVKNGLGIAIISTSKGVLTDKEAAEHGVGGEVIAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: H34_TETTS
Sequence: MARTKQTARKSTSIKAPRKQLAAKAARKSAPISGGIKKPHKFRPGTVALREIRKYQKTTDLLIRKLPFQRLVRDIAMEMKSDIRFQSQAILALQEAAEAYLVGLFEDTNLCAIHARRVTIMTKDLHLARRIRGERF
What is the function of this protein?
Macronuclear replacement variant which replaces conventional H3 in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  Functions redundantly to H3. 3.  H3. 4 deposition is mainly transcription-associated, DNA replication-independent.  Although not essential for vegetative growth, minor H3 variants are required for producing viable conjugation progeny by affecting late developmental stages of conjugation.
What are the official names of this protein?
Histone H3.4, Minor histone H3 variant.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes mainly to the large, transcriptionally active, somatic macronucleus (MAC) and only faintly to the small, transcriptionally inert, germ line micronucleus (MIC).
Protein: PETD_LOTJA
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLVTVPFLENVNKFQNPFRRPVATTVFLIGTAVSLWLGIGATLPIEKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PYRG_CLOAB
Sequence: MKTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLKVSIQKFDPYINVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDENLSKNSNVTTGKVYWSVINKERRGDYLGGTVQVIPHITNELKERVYRVAKEKDVDVVITEIGGTVGDIESLPFLEAIRQIKYEVGFGNSCFIHVTLLPYLRKAGEIKTKPTQHSVKELRGIGIQPDIIVCRTEKEISKDVRSKIGLFCNIDGDSVISNLDAENLYEVPLMLHDQGLDSLVCKKLELECQEVDNSEWESMVKNIKSLSGEVTIGLVGKYVELHDAYISVVESLNHGGFANNVSVNVKWINSEEVTKDNVDSVLSDVDGILVPGGFGDRGIEGKIEAIRWARENKIPFFGICLGMQCAVIEYARNVLGLEGAHSSEIDPQTKYPVIDLMPDQKDIDDKGGTMRLGLYACKLSKDTNAYDAYEEEVIYERHRHRYEFNNEFRKRLTEEGLILAGTSPDDRLVEIVEIKDHPWFVGVQFHPEFKSRPNRPHALFRDFIKVACTVKEK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: FRHG_METTH
Sequence: MAEENAKPRIGYIHLSGCTGDAMSLTENYDILAELLTNMVDIVYGQTLVDLWEMPEMDLALVEGSVCLQDEHSLHELKELREKAKLVCAFGSCAATGCFTRYSRGGQQAQPSHESFVPIADLIDVDLAIPGCPPSPEIIAKAVVALLNNDMEYLQPMLDLAGYTEACGCDLQTKVVNQGLCTGCGTCAMACQTRALDMTNGRPELNSDRCIKCGICYVQCPRSWWPEEQIKKELGL
What is the function of this protein?
Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.
What are the official names of this protein?
Coenzyme F420 hydrogenase subunit gamma, 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit gamma, FRH.
What is the protein family that this protein belongs to?
Belongs to the FrhG family.
Protein: YIDC_CAMJE
Sequence: MNNSNNIFQQKRILLAVVISFLFFVIYDYFFIPKQPLKIEQNITQKNQQNTSINNTPNIQNATTNTPSAALVSQDSVISKVQSKHFEAQIDSFGRISAFYLKDRKYQNEKGEFINLVSKENSPYPLEMRFSDPSINSEAFKIPYVANASNLFVDENGSQVLKLTQNLSGLKIEKDITFYPKGNYEIEVKLSKNANYFISPGYRPNIAVDSYTVHGALVMDNKETIETYKDGDVEKDESANNVVMTSAFDRYYATFFYNFDKPLNVAISKDANQNPIVFAYSDNEFKAGGYIGSKEHVILRSIDPRLEAVVEYGWFTFIAKPMFEFLNFLHQYIGNWGWAIVVMTLIVRIILFPLTYKSMISMNKLKDLAPKMKDIRERYKGDPQKMNMHMMELYKKHGANPMSGCLPILLQIPIFFAIYRVLLNAIELKAAPWAFWIHDLSVMDPYFILPILMGATMFLQQLITPMTIQDPMQAKIMKFLPVIFTFFFITFPAGLTLYWFVNNLCSLVQQWVINKIFAKEHHKKTSGA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAC_ECO27
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSWSGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVSTGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMKRHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNNL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: MDTI_ECOLU
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CODY_STRP3
Sequence: MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLNLQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSB_ECOLC
Sequence: MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: MRKF_KLEPN
Sequence: MKPQPFTLELSNCQLRHDGGAADKDEVRMVNVRWIDGFMVNSVSNENAGYLANTRADGASHIFLALSTNDNNTLNKSNKIVPADPQQNRVPLVEKAVDGGIFTYYIGYVTPAPEKATSGPLTSWATWELVYN
What is the function of this protein?
Appears to affect the stability of the intact fimbriae on the cell surface.
What are the official names of this protein?
Protein MrkF.
What are the subcellular locations of this protein?
Fimbrium.
Protein: SFL2_CANAL
Sequence: MSKKNPGDPRVKKNAFVHKLYTMLHDPALSHLIWWTNRNGEQNTFALCPGKEFADCLTQYFKHGNVASFVRQLHMYGFHKVSDPLPITYPPNGNNNNNNNNKEVPPVWEFKHSSGRFKRGDETSLVYIKRRSSSNHTSGSTIYAEPIYNPLLTNPYNQPQFMYQDYSMGPPVEVQQFYNYQNQPLMYYQQPPGQVPPPPPPSLPPHQQPEMALQYHQYNNYQQPPPAPPAPPPQPGNVLFGYQQVAPPQQPGSTVQQIPANAPPTLDQTQPLSYTPQLEYQQQQYPQPPLPPPPPQLQLQTSPGIPKVNDNLSRPSPNEQHLQFRKIWPDENNEANSKPRNPSLMFDPLLRVNSEGSPKTQPNHSVSLLNNEVRSESSTSSSSTTVTSTALPPPSAIDRSVSLVGGSPFDLSSRMNNQQSFNRTPSISTPPTQNGRLPKISSPLIPSNTESQSPTMVTGTDNDVGVTSKGSTSIISVSKKPSVFSNSLQERLRPSMFEYHPIGNNLSKDVLTIPKISTNSNSGSRTTSQSSMSSASALSSKKSSLSSISSTHGNLSILNSTNYRSTSVGGSGSGPFSTSTSTSTTSPTLSSLLHHPQHEPQNSTIANGTSIRSSISSSQSISSPPLTTTTTTTTTDQRQLSNSPISRQQQQQPNNNTNKKVSVTSLLLPSHSQSQGYAQPLYKSSVIAEEENSTTSSGGGYRSKSDDDTDNMNK
What is the function of this protein?
Transcription factor that plays a role of activator of filamentous growth and which is involved in invasive growth at a high temperature.  Required for human oral epithelium colonization and damage.  Promotes filamentous growth in EFG1- and FLO8-dependent manners.  Antagonizes functions of SFL1.
What are the official names of this protein?
Transcription factor SFL2.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to the nucleus in both yeast and hyphal cells.
Protein: HIS82_PSYA2
Sequence: MSESKIDNRLWSSKARNLSPYVPGEQPQHDDLCKLNTNENPFPPSPKVGEAITKVLAQQADDLRLYPAPESEELRGALAALYNLDINQVFVGNGSDEVLALVFASFFLKNRPVLAPDISYSFYPVYANTFGIELVQIPLEADFSISPDAYRRPCSGIIIANPNAPTGLLLSLADIRKLAGEHSDSVIVIDEAYIDFAQLEEASAESQMSAISLINEFDNLLVTQTFSKSRSLAGLRVGMAFGNASLIEALTRMKNSFNSYPLDKLAQAGATASVLDVEYFEQTCQQVIDLRTSLTAELTALGYDVLPSHANFVFARPHDGAASQVAEVLREQGIIVRHFDKPRINEYLRITIGTPSQHERLINALKALQAVADVEAS
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: BODG_RHILO
Sequence: MLTHALIGDEGRTIELGWQGGRRTRFHAMWLRDNALDDKTRSAGNGQRLITILDIPAETRIGAAEIKGGALEVSFVPEGKTVSFPAQWLSANAYDRDELREPGWTGDVIQRWTKATMQNSVPRASYKAAFHGRSVLREWLSAVRTYGFAVMDGLPAESGALCKVSDLFGYIRETNYGRWFEVRAEVNPNNLAYTNLGLQAHTDNPYRDPVPTLQILACVENTVEGGESSVIDGFAVAAALQAENPEGFRLLSSCPARFEYAGSSGVRLQAKRPMIELGPDGELICIRFNNRSLAPVVDVPFADMDAYYAAYRRFAELIEDPDFEVTFKLQPGQAFIVDNTRVMHARKAFSGTGKRWLQGCYADKDGLLSTLAAIEHSFKEAAE
What is the function of this protein?
Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
What are the official names of this protein?
Probable gamma-butyrobetaine dioxygenase, Gamma-butyrobetaine hydroxylase, Gamma-BBH, Gamma-butyrobetaine,2-oxoglutarate dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-BBH/TMLD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNTX_CENLI
Sequence: KYCYNDDDCKSECMVVKYCQQGTCYCKGN
What is the function of this protein?
May act as a toxin.
What are the official names of this protein?
Orphan peptide CllNtx.
What are the subcellular locations of this protein?
Secreted.
Protein: IXTPA_CUTAK
Sequence: MSRIVLASNNAKKLVELRRTFEGADTEVEIVGLSEVSDAPAPEETGRTFVENALIKARAAAHETGLPALADDSGLEVDALNRMPGIRSARWSGPHAHDERNLQLLLDQTFDLPDERRHGRFVCAMAFVDPDGTEITKVATMEGRIISEARGKNGFGYDPMFVPDAQPGDLTSAEMTPEVKDAISHRGQAVRAIVPAVVAHLEGR
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: CSN5_CANGA
Sequence: MDDFPSLNVSDLESKLLDYNIRDYEVQNSKHKNNIAGNEKESIDQLSLLNQVCSLKNRKAIDSTKNSPLFYQNVLLSKLACSKILCHATKGGNIEVMGMLLGNVIGNTFVIFDCFELPVEGTETMVNAHMESYEYMVQFYHEMVERSYTRNEENLNIIGWYHSHPGYDCWLSNIDMQTQSLNQQHQDPYLAIVVDPHKSKNDQKVRIGSFRTYQDQNDDTNFYELNTTVFDSELNKLENPLSVKIPFNSIESRNLESNYLQKLSETVKQWRNFKIMEKIENTAHTEDTTTNKSISTPGRIIQTAHEFAFAATSNGNGSRVNIMRSNSVSSIGSSSDIEMEDRNCSAFDSVASSINTIADPSRTSSIHTQMNNQNNQQERNSPKRPHILPAIQSSRYGVIFEGKDRPENKNFNIRTASAQDAFESKCIDDFHESLKNDYLTQKEILLRLKLRQYYRLRMYRDMFSK
What is the function of this protein?
Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
What are the official names of this protein?
COP9 signalosome complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NTPPA_PORG3
Sequence: MLDNLKKYKIVLGSQSPRRKELLSGLDIRFEQKAMPDIAEDYPAGLDPEKVPLYLARMKAEAYRSKGMMQDSTLLITADTVVIVDGAILGKPQDREEAARMLRTLSGRTHQVVTGVCISHRWETRAFSCSSLVTFAHLSDEEIDYYLERYRPYDKAGSYGIQEWIGYIAIQRVEGSFYNVMGLPVHLLYNELKDFGESN
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_RHOP2
Sequence: MPVRQLPETIVNRIAAGEVVERPASVVKELVENAIDAGASRIDIFSDGGGRRKIVIADDGSGMTRADLALAVDRHATSKLDDEDLLQIRTLGFRGEALPSIGAVARLTITTRHAGEPHAWTLGVEGGDKSPIAPAALSQGTRVEVADLFFATPARLKFLKTDRTEAEAIRDVVRRLAMARPDIAFTLAGEERAPVTWAAALPGAPGQLIRLGDILGADFRANAIEVRSEREGVAVEGFAASPALTRANALGQYLFVNGRPVRDKLILGAVRAAYSDYLPRDRHPVVALFVTLESREVDANVHPAKTEVRFRNAGLVRALIVHALKEGLAREGRRTAANSAGSVISTFRPASMPAANWDWRASPSYPVGGSAIDAPSFAERPQAAFDVGGPSADIRTHEVAPDLLDRPLGAARTQIHETYIVSQTRDGLIVVDQHAAHERIVYERLKASLAANGVQRQILLIPDIVEMDEATVERLVARADELAQFGLVVESFGPGAVAVRETPSLLGKTDAASLLRDLAEHMAEWDEALPLERRLMHVAATMACHGSVRAGRVLKPEEMNALLREMEATPNSGQCNHGRPTYVELTLTDIEKLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: FETP_SALPA
Sequence: MSRTIFCTYLQRDAEGQDFQLYPGELGKRIYNEISKDAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVSFLFEGKDVHIEGYTPEDKK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: RPOB1_NOCFA
Sequence: MLEGRIVTVSSRTESPLAAPGVPGAPRRLSFARIREPLAVPGLLDIQTESFGWLIGAPDWCARAAARGTEPVAGLAEVLAEISPIEDFAGTMSLTLSDPRFEEVKASVEECKDKDLTYAAPWFVTAEFVNNNTGEIKSQTVFMGDFPMMTAHGTFVVNGTERVVVSQLVRSPGVYFDHAIDKGSEKDVHSARVIPSRGAWLEFDVDKRDTLGVRIDRKRRQPVTVLLKALGWSAERIAERFGFAPLIMASLAKDNVAGTDDALLEIHRKLRPGEPPTKESAQNLLANLFFTEKRYDLARVGRYKIDKKLGLRAPGAPRVLTEDDIAATIEYLVRLHAGERTMIAPGGVEVPVEVDDIDHFGNRRVRTVGELIQNQIRVGLSRMERVVRERMTTQDVEAITPQSLMNIRPVVAAMKEFFGTSQLSQFMDQRNPLASLTNKRRLSALGPGGLSRERAGLEVRDVHYSHYGRMCPIETPEGPNIGLMGYLSVYARVNPFGFVETPYRRVVDGRVTDEVDYLTADEEDRHVVAQANEPLDAEGRFLAARIPVRRKNSEVELVDSAAVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLIRSEAPIVGTGMELRAAVDAGDVVVNEKAGVVEEVSADYVTVMADDGTRKSYRMRKFNRSNQGTCSNQRPIVDEGQRVEAGQVLADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSQRLVEQDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDDDDLPPGVNELVRVYVAQKRKIQDGDKLAGRHGNKGVIGKILPTEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWIGKAGWKVEGNPEWAKDLPEEMWEAPADSNIATPVFDGAREEELTGLLGSTLPNRDGERMVDDNGKAVLFDGRSGEPFPYPVAVGYMYILKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDVVGRVKVYEAIVKGDNIPEPGVPESFKVLLKELQALCLNVEVLSAGAAVELAHGVDDDHERTAANLGINLSRAESITETELSG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta 1, RNAP subunit beta 1, RNA polymerase subunit beta 1, Transcriptase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.