PharMolix/UniProtQA huggingface dataset:
Protein: PYRB_RUMCH
Sequence: MNLKSKDLLGLRDISAEEIEYILNTAKTMKCIVTSNNKKTAHLQGKSIITLFYENSTRTRLSFELASKYMGASAANISASSSSVQKGETLIDTGKTIDSMGSDIIIMRHPMSGAPHLLAKNVKSSVINAGDGMNEHPTQALLDMFTILEKKGTLKGLKVAIIGDILHSRVARSNIWGLTKMGAEVNVAGPATLIPPEIEKIGVNVFSTVQEAMLDADVVMGLRIQLERQKKGLFPTIREYSRFFGVDDKRLKLAKEDAIVLHPGPVNRGVELSSSVTDGEQSFIDEQVTNGVAVRMALLYLLTRRGIVNEVTD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TRMFO_GEOSL
Sequence: MTGAVTIIGGGLAGCEAAWQIAGRGVRVVLREMKPQRYSPAHHLSGLAELVCSNSLRGESLENAVGLLKEELRRAGSLIMAAADATRVPAGGALAVDRELFSSYVTERIEGHPLIELVREEVTELPAEGVLVIASGPLTSDALAERLKQITGDSLYFYDAIAPIVAADSLDSDKVFRASRYGKGDGDDYLNCPLSEEEYERFVDAVLAAEKVPARDFEKVVHFEGCMPVEEMAERGRETLRFGPLKPVGLTDPRTGREPHAVVQLRAENREGTLFNLVGFQTKLTWPEQRRVFRMIPGLESAEFVRLGSMHRNTFINAPTLLEPTFRLKGDPRTFFAGQITGVEGYVESAGSGFLAGINSARLVRGEDPAVPPPVTALGALVAHITTAPARHFQPMNVNYGLFPPLEGKVKKKDRRGRLAERALAELDHWLATV
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_CHESB
Sequence: MTDRTAFYAGSFDPLTNGHLDVLKGALELADTVVIGIGIHPGKKPLFSYGERVALIERSAKDELGADGGRIKVVAFDNLVIDAARVHGASIMIRGLRDGTDLDYEMQMAGMNQTMAPELLTVFLPASPSVRTVTATLVRQIASMGGNVAPFVPAVVAAALKEKFSA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAA_SALPB
Sequence: MTIFDNYEVWFVIGSQHLYGAETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTSPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLSILNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKEAHTRIGAWMRQAVSKQDTRQLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSIGDGDINALIDEYESSYTLTPATRIHGDKRQNVREAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKEDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALDLNDMRQFAEIHDIEIAVIDNDTRLPAFKDALRWNEVYYGLKR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: CRN2_PHYIN
Sequence: MVKLVCAIVGVAGSAFPVDTDASQLVGDLKKAIKAENAMTFTGDAKDLQLFLAKQPVDDESGKEVVPVYRPSAEEMKEESFKWLPDEHRAALKLVEGESDDYIHALTAGEPILGSKTLTTWFYTKNNMELPSSEQIHVLVVVPDGAGGSASDTSRMDRLFDKVDKVYEHTVLSKRTRYVHSEMNSAKGNILLNDLKIRISPVDTVKFAGGVPTPAKEFKWKSDRTEEQQKEPYREYVVANIGDVLTNNKLCVVGVEKGVNILTVEVPGRDIVLAGRTDMIVLSDIAQKFPHYLPHLPGVRMLIEVKKVVTTASEFQALSELIALDIIATESVMALLTNLTNHWQFFWVSRKSDDRVIIETTTLIAPGEAFAVIRTLLDQSPSAGAEVSLPCFEKPVKRQKLSQLLPSISEASGSSGIRESIERYYDIASMLGPDLEMARAVASQVARSIPTLSYFS
What is the function of this protein?
Secreted effector that effector that induces cell death when expressed in host plants (PubMed:19741609, PubMed:20847293).  Induces the expression of defense response genes in tomato (PubMed:12840044).
What are the official names of this protein?
Crinkler effector protein 2.
What is the protein family that this protein belongs to?
Belongs to the Crinkler effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: UBP38_MOUSE
Sequence: MDKILEGLVSSSHPLPLKRMIVRKVVEFAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLQQGYHSVDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPVLCARLSDLLTDFVQCVPKGKLSVTFCQQLVRTIGHFQCVSTQEKELREYVSQVTKVSTLLQNIWKAEPSTLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHVIVPHIVNLVHSFRSDGLPSSTAFLVQLTELVHCMMYHYSGFPDLYEPILEAVKDFPKPSEEKIKLILNQSAWTSQSNALASCLSRLSGKSETGKTGLINLGNTCYMNSVLQALFMATEFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEEKILRVQSSHKPSEGLDCAETCLQEVTSKVAVPTESPGTGDSEKTLIEKMFGGKLRTHICCLNCGSTSHKVEAFTDLSLAFCPSPSVEDLSFQDTASLPSAQDDGLMQTSVADPEEEPVVYNPATAAFVCDSVVNQRVLGSPPVEFHCAESSSVPEESAKILISKDVPQNPGGESTTSVTDLLNYFLAPEVLTGENQYYCESCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRTASFSSLSQSWSVDVDFTDINENLPKKLKPSGTEEAFCPKLVPYLLSSVVVHSGVSSESGHYYSYARNITGTESSYQMCPQSESLALAPSQSCLLGVESPNTVIEQDLENKEMSQEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQSRANGIDSDNPASGVWANGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGGGGFNTVGRLVF
What is the function of this protein?
Deubiquitinating enzyme exhibiting a preference towards 'Lys-63'-linked ubiquitin chains.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 38, Deubiquitinating enzyme 38, Ubiquitin thioesterase 38, Ubiquitin-specific-processing protease 38.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: CQ10B_HUMAN
Sequence: MAARTGHTALRRVVSGCRPKSATAAGAQAPVRNGRYLASCGILMSRTLPLHTSILPKEICARTFFKITAPLINKRKEYSERRILGYSMQEMYDVVSGVEDYKHFVPWCKKSDVISKRSGYCKTRLEIGFPPVLERYTSVVTLVKPHLVKASCTDGRLFNHLETIWRFSPGLPGYPRTCTLDFSISFEFRSLLHSQLATLFFDEVVKQMVAAFERRACKLYGPETNIPRELMLHEVHHT
What is the function of this protein?
Required for the function of coenzyme Q in the respiratory chain.  May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity).
What are the official names of this protein?
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COQ10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: TKN2_OCTVU
Sequence: MIRVGLILCCIFIVGVFEASSADDILTAHNLIKRSEVKPPSSSEFVGLMGRSEELTRRLIQHPGSMSETSKRGPPKKGDFNPNELKPESNIC
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Tachykinin-2, OctTK-II, Tachykinin II.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_YERPN
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIIVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKNANTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKDGDVVVGSETRVKVVKNKIAAPFKQAEFQILYGEGININGELVDLGVKHKLIEKAGAWYSYNGDKIGQGKANASNYLKENPAIAAELDKKLREMLLNGGNGEQPVAAATAEFADGADETNEEF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYB7_ARATH
Sequence: MGRSPCCEKEHMNKGAWTKEEDERLVSYIKSHGEGCWRSLPRAAGLLRCGKSCRLRWINYLRPDLKRGNFTHDEDELIIKLHSLLGNKWSLIAARLPGRTDNEIKNYWNTHIKRKLLSKGIDPATHRGINEAKISDLKKTKDQIVKDVSFVTKFEETDKSGDQKQNKYIRNGLVCKEERVVVEEKIGPDLNLELRISPPWQNQREISTCTASRFYMENDMECSSETVKCQTENSSSISYSSIDISSSNVGYDFLGLKTRILDFRSLEMK
What is the function of this protein?
Transcription factor involved in the negative regulation of flavonol biosynthesis.  Represses the early phenylpropanoid genes, phenylalanine ammonia-lyase (PAL), cinnamate 4-hydroxylase (C4H) and 4-coumarate-CoA ligase (4CL), as well as the flavonoid-specific genes, flavonoid 3'-hydroxylase (F3'H) and dihydroflavonol 4-reductase (DFR) (PubMed:24319076).  Plays a role in seed germination inhibition.  Negatively regulates the expression of the abscisic acid (ABA) signaling transcription factor ABI5 in seeds (PubMed:25053018).
What are the official names of this protein?
Transcription factor MYB7, Myb-related protein 7, AtMYB7, Myb-related protein Y49, AtY49.
What are the subcellular locations of this protein?
Nucleus.
Protein: LFTR_BORA1
Sequence: MRIPWLEADTPFPPAEQALKEPNGLLAAGGELNTDRLRAAYAKGIFPWYSEGEPLLWWSPDPRMVLACADFAPSHSLRKTLRRLARAEQAGDTRIQVRVDTAFARVMAACAGRRDGQAGTWITPEVQAAYCAWHEQGQAHSIETWIDDHLVGGLYGISLGGMFFGESMFAHATDASKIALAYLVAFLTRHEVDWIDCQQQTRHLASLGARPLPRAQFLQHVARVLAKPAPPWRVGVLRHAGDIVDSANQR
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARFG3_RAT
Sequence: MGDPSKQDILAIFKRLRSVPTNKVCFDCGAKNPSWASISYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNANASSFFHQHGCATKDTNAKYNSRAAQLYREKIKTLATQATRRHGTDLWLDSCAAPPASPPPKEEDFFASHASLEVSGATQASAQPEPASSTPWGLETTPEKHEGGPGQGPSVEGLNTPGKTAPAEVSSIIKKKPNQAKKGLGAKKGSLGAQKLTNTSFTEIEKQAQAVDKRKEQEDLARGTPKEESIVSSLRLAYKDLEIHKKQDERLNLSGQKKAEAERLGMGFGSCRGGISHSVTSDMQTIEQESPTLAKPRRKYQEDPEDSYFSSSSKWSEQSSSRYFDDPMELRSSHFSSWDDSADSYWKKDSSRDPEPATKSTGSSDRPSSRRKPEYEPVGNTDEAQKKFGNVKAISSDMYFGIQSQTDFETRARLERLSTSSSISSADLFDEQRKQTTGNYNLSNVLPNAPDMAQFKQGVRSVAGKLSVFANGVMTSIQDRYGS
What is the function of this protein?
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1).  Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity).
What are the official names of this protein?
ADP-ribosylation factor GTPase-activating protein 3, ARF GAP 3.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
Protein: CYB_LEPED
Sequence: MTNIRKNHPLLKIINNSLIDLPTPPNISSLWNFGSLLGACLTIQIITGLFLAMHYTADTTTAFSSVTHICRDVNYGWTIRYLHANGASVFFLCLFIHVGRGLYYGSFTLLETWNVGIILLFSVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVSKATLTRFFALHFVLPFVILALVMIHLLFLHETGSNNPLGTSSNSDKIPFHPYYTTKDFLGLLLLILLLMVLTLFYPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVMALILSILILAIIPLLQPNKQQTMMFRPLSQFLFWILVADLLTLTWIGGQPVEDPFITIGQVASILYFLLMVLIMPTTCLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL35_CHLPD
Sequence: MPKMKSHRGACKRFKATASGKIKHERMNGSHNLEKKNRKRSRRLHQATILDSAKEKQIRRMILA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: LPTD_PSEE4
Sequence: MALKSPAFRRKFPLLVTGGLLALQPLATSFVVAAEQFDCQVSAAGGWDCKPKATGNLPPRPVHPGAAAASSGAEAPGEVGEAQAEKPMLVTESKGRGLKSRSEDYSHLDWVPREKLTAAQLAETGPYCGGAYIEPTRPGMNDTTPKDESPTYINAKVSKYQQEQQIATLAGDVVMRQGSMQAEADEANLYQAENRGELKGNVKIRDNGSLVVGDEAQIQLDTGEARVDNAEYVMHKSHIRGNALYAKRAENAIIRLKDGTYTTCEPGSNAWQLKGNNITLNPATGFGTATNVTLRVKDFPVLYTPYIYFPIDDRRQSGFLPPSFSTSSDTGFMLVTPYYFNLAPNYDATLYPRYMAKRGMLMEGEFRYLTKSSEGQFGGAYLNDESDDRKLQTDYKKERWMVNWQHKGGLDERLMTEVDYTDISDPFYFQDLETDQIGVEKRDFVNQQGALNYRGDNYTARLNVHAYEMATISQITPYDKLPQVTFNGTLPFHPSGLDFGYETEAVRFERDLKNDLVFDKDGKPDESIGVVKDANGEVIGGRRIDESLRGIARANGTRLNAAPSISLPMEASYGFLTPKLKYVYTHYDLDLNSRGQAQAAQDSANPAYGTYNSAINRNVPIFSVDSGLYFDRNTQLFGTNYRQTLEPRLFYLYVPYKDQRDIPLFDTGETLFNYASLFRDNRFAGTDRIGDENKLSLGVTNRWIEDNGFQRQRFSIGQAYYFKDRKVQLPGIDYRTRKDSQSDVSPYALEYEYAFNRDWRFNSDFNWDPDSRSTRSGSAMFHYQPEDNPNKIVNLGYRYRNDTITYDSLTGAWKVGGGDYGSPGDANYIKDYYKIQQHDFSVIWPIVPQWSVIARWQHDYNRNRTLEAMGGFEYDSCCWKLRLINRYWLDYDDFSQATPTNEKGDHGVFLQVVLKGLGGVVGNKVESFLDQGIQGYRTREEQAY
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: A2GL_HUMAN
Sequence: MSSWSRQRPKSPGGIQPHVSRTLFLLLLLAASAWGVTLSPKDCQVFRSDHGSSISCQPPAEIPGYLPADTVHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGNPWICDQNLSDLYRWLQAQKDKMFSQNDTRCAGPEAVKGQTLLAVAKSQ
What are the official names of this protein?
Leucine-rich alpha-2-glycoprotein, LRG.
What are the subcellular locations of this protein?
Secreted.
Protein: FMT_PROM4
Sequence: MKIVFWGTPEFSVPILEALINSDHDVVGVVTQPDRRRSRGNKLIHSPVKTVALENNIPVLTPQNIRQESLIQQKIINLKADLNLVVAFGQILPLLILDSPPLGSWNIHASLLPRWRGAAPIQRAILEGDILTGICIMLMEEGLDTGPILLQKEFPIDVLRNSYQISSDLSSLSATTIIEALELIRTSSHFTKNLVEIYPKLIKQDVVNCDPIYAKRLTKKEFQIDWKRLSEEIHRTIMGLYPAAYTSLNGKRIKLHNSIPLTPSFSTYISNNYDSYIIDYISTSSYPGEILAVIPKLGFIVGTASYPILILNGQMEGRNSVSADILAKQIDLSIGIRFD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GATB_TROW8
Sequence: MSEIVTYEDALKDFEPIIGLEVHVELSTQTKLFSSAPNIAGPLASCASQGPNTLVTPVCLGLPGSLPTVNERAVDYGIALGLALGCSIADELIFARKNYFYPDLPKNYQISQFDSPLAYDGKLEVETESGDVFFVEIERAHLEEDAGKLAHKSSTGRIQGAQYSLIDYNRSGVPLVEIVSRPVFADRCAPQVARAFVELIREIVLSLGVSNARLERGNIRCDANVSLRPRGLGAGILPNRTETKNLNSLRSIERAIRYEIQRQATLISSGELVRQETRHWREDRGITLSGRVKADSHEYRYFPEPDLLPIPIPSDKVEAIRLSMPEHPLALRRRLKAEWKFSDLQFRDVLNSSVLKQVDETVRAGATPDGAKKWWTGEITRIASQRRCNASDLISPEAVAEIELLISKGILNDSLARKVLAAVIDESLSVQQAIEKYDLSLTESASVERVLEKVLSENQEVVQKVISGKTQAVGVLVGSCMKTLGGKADASKLRQTILNRLLPR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RUVB_STRA3
Sequence: MTRFLDSDAMGDEELVERTLRPQYLREYIGQDKVKDQLKIFIEAAKLRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAIEKSGDLVAILNDLEPGDVLFIDEIHRMPMAVEEVLYSAMEDFYIDIMIGAGETSRSVHLDLPPFTLIGATTRAGMLSNPLRARFGITGHMEYYEENDLTEIIERTADIFEMKITYEAASELARRSRGTPRIANRLLKRVRDYAQIMGDGLIDDNITDKALTMLDVDHEGLDYVDQKILRTMIEMYNGGPVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVATDKAYEHLGYQRFDK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PRO_HTL3P
Sequence: MGKTYSSPVNPIPKAPKGLAIHHWLNFLQAAYRLQPGPSEFDFHQLRKFLKLAIKTPVWLNPINYSVLARLIPKNYPGRVHEIVAILIQETPAREAPPSAPPADDPQKPPPYPEHAQVEPQCLPVLHPHGAPATHRPWQMKDLQAIKQEVSSSAPGSPQFMQTVRLAVQQFDPTAKDLHDLLQYLCSSLVASLHHQQLETLIAQAETQGITGYNPLAGPLRVQANNPNQQGLRREYQNLWLSAFSALPGNTKDPTWAAILQGPEEPFCSFVERLNVALDNGLPEGTPKDPILRSLAYSNANKECQKLLQARGQTNSPLGEMLRACQTWTPRDKNKILMIQPKKTPPPNQPCFRCGQAGHWSRDCKQPRPPPGPCPLCQDPAHWKQDCPQLKADTKGSEDLLLDLPCEASHVRERKNLLRGGGLTSPRTILPLIPLSQQRQPILHVQVSFSNTSPVGVQALLDTGADITVLPAYLCPPDSNLQDTTVLGAGGPSTSKFKILPRPVHIHLPFRKQPVTLTSCLIDTNDQWTILGRDALQQCQSSLYLADQPSSVLPVQTPKLIGLEHLPPPPEVSQFPLNRSASRP
What is the function of this protein?
The aspartyl protease mediates proteolytic cleavages of Gag, Gag-Pro and Gag-Pro-Pol polyproteins during or shortly after the release of the virion from the plasma membrane.  Cleavages take place as an ordered, step-wise cascade to yield mature proteins.  This process is called maturation.  Displays maximal activity during the budding process just prior to particle release from the cell.  Hydrolyzes host EIF4GI in order to shut off the capped cellular mRNA translation.  The resulting inhibition of cellular protein synthesis serves to ensure maximal viral gene expression and to evade host immune response (By similarity).
What are the official names of this protein?
Gag-Pro polyprotein, Pr76Gag-Pro.
What are the subcellular locations of this protein?
[Matrix protein p19]: Virion. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p15-pro]: Virion.
Protein: COLI_SQUAC
Sequence: SYSMEHFRWGKPMGRKRRPIKVYPNSFEDESVENMGPEL
What is the function of this protein?
Anorexigenic peptide.  Increases the pigmentation of skin by increasing melanin production in melanocytes.
What are the official names of this protein?
Pro-opiomelanocortin, POMC, Corticotropin-lipotropin.
What is the protein family that this protein belongs to?
Belongs to the POMC family.
What are the subcellular locations of this protein?
Secreted. Note=Alpha-MSH and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms.
Protein: YTXB_BACSU
Sequence: MKRKTAVKWLAVLAGAGLLYWGNKTYLNVSPKEIRVWVLSFGVFAPLMFIGISIVRPLVLFPVSVISIAGGLAFGPLLGTLYTLFGSMCASAVSFFAAGLFSAKKNGHYERLEAIQKQMEDNGFFYIFLLRILPINFDFVSYAAGLSNVKALPYFAATAVGIIPGTIALNVLGASFLAGNLPAFFMVLALYIVFISLPFIFRKKMQNLFQESN
What are the official names of this protein?
TVP38/TMEM64 family membrane protein YtxB, ORF-213.
What is the protein family that this protein belongs to?
Belongs to the TVP38/TMEM64 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YO024_YEAST
Sequence: MSKLSSYPHAADFINMEEPPKSKEFFDDLCAVPNLLKRRFPNSRRSTHYCEALNYSRKKLPVVLSKMTLQELRHNMSTFFLQEKDQINIYDTCKVIDMGDRVLLETMPPQPRDLFEKLHASKTNLVVQTAALDEPLLTVKAELQSSSFPQKSSLFLYEDYKKFIYQQLDMFS
What are the official names of this protein?
Putative uncharacterized protein YOL024W.
Protein: GREA_HAMD5
Sequence: MTQIPMTLRGAEKLREELQHLKSVLRPQIIAAIAEAREHGDLKENAEYHAAREQQGFCEGRIQEIESKLSHAQIIDVTKIANKGIVIFGATVTVLNTHSEEKKIYQIVGDDEANFKKDLISVNSPIARGLIAKKISDVAVIHTPGGEVEYEILDVKYC
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: H2B1H_HUMAN
Sequence: MPDPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B type 1-H, H2B-clustered histone 9, Histone H2B.j, H2B/j.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FABH_BRUO2
Sequence: MIRSVVRGIGSALPKRVMKNTDFEGIVETSDEWIVQRTGIRERHIAGKGETTVSLGAAAARAAIENAGLQPSDIDLVLLATSTPNNTFPASAVAIQRELGITRGFAFDLQAVCSGFIYAITTADLYIRGGMARRVLVIGAETFSRILDWTDRTTCVLFGDGAGAIVLEAAEGHGLTSDRGILAANLRSDGNHKEKLYVDGGPSTTQTVGHLRMEGREVFKHAVGMITDVIEASFEATGLTAEDIDWFVPHQANKRIIDASAKKLHIAEEKVVITVDRHGNTSAASVPLALATAVADGRIKKGDLVLLEAMGGGFTWGAVLVRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.