PharMolix/UniProtQA huggingface dataset:
Protein: CLPX_NEIMF
Sequence: MSNENRTCSFCGKSKSHVKHLIEGENAFICDECVSNCIEILHEDGNDGTPSESAGGEPEESGKLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDEIDKISRKGDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQEFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKDENADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEELDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVFEP
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: EFG_PROMS
Sequence: MARDFPLERVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERGITITAAAISTSWQDHRINIIDTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSVPRMVFVNKMDRTGADFLKVNKQIKDRLKANALPIQLPIGAEGDLTGIIDLVANKAYLYKNDLGTDIEEAPIPSEMEEEAAEWRFKLMESVAENDEELIEIFLETGELSEEQLKKGIREGVLKHGLVPVLCGSAFKNKGVQLVLDAVVDYLPAPVDVKPIQGVLPSGKEDIRPSDDNAPFSALAFKVMSDPYGKLTFVRMYSGVLSKGSYVMNSTKDAKERISRLVILKADEREEVDELRAGDLGAVLGLKNTTTGDTLCNTEDPIVLETLFIPEPVISVAVEPKTKGDMEKLSKALTALSEEDPTFRVSTDPETNQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYRETIRSSSKGEGKYARQTGGKGQYGHVIIEMEPAEVGKGFEFVNKIVGGAVPKEYIGPASNGMKETCESGVLAGYPLIDVKVTLVDGSFHDVDSSEMAFKIAGSMAFKDGVKKCNPVLLEPMMKVEVESPDDFLGSVIGDLSSRRGQVEGQSVDDGLSKVQAKVPLAEMFGYATQLRSMTQGRGIFSMEFANYEEVPRNVAEAIISKNQGNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_RICPU
Sequence: MLKLLSEIGPVIAFFAGFFYGGGIQHATLYMLITSVICITLCYVIDKKVSKLSIISTTVLLVSGSITLISGDSMYIKIKPTILYVIFGIIFLMSGIRKNPFIKYALESIVRLKEESWITLSYRTAAFFFFMAVVNEVVWRNCSDETWVKFKVFGVIPITFIFILLQLPLLLKNKLPDSKI
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYP_VIBC1
Sequence: MRTSNYLLSTLKETPNDAEVVSHQLMLRAGMIRKLASGLYTWLPTGLRVLRKVENIVRQEIDNAGAVETLMPVVQPFELWEETGRSEKMGPELLRFTDRHTRPFVLSPTAEEVITSLVRNEVSSYKQLPLNLYQIQTKFRDERRPRFGVMRAREFCMMDAYSFDIDKEGLEKSYQAMHDAYCKAFDRMGLEYRPVLADSGAIGGSGSQEFHVLAESGEDLIAFSTESDYAANIEKAEAAAPAGERAEPTQEMTLVDTPNAKTIAELVEQHGLAIEKTVKTLFVKASDEVDADIIALIVRGDHELNEVKAENLPQVASPLEMATEEEMRALIGAGAGSLGPVGLELPFIVDRSVAVMSDFGAGANIDDKHYFGINWGRDVELGQVEDLRNVVEGDPSPCGQGTLMLKRGIEVGHIFQLGNVYSEAMNCGVLGPDGKNVILEMGCYGIGVSRVVASAIEQNHDKYGIIWPDALAPFQVAIVPMNMHKSEEVKEAAEKLYAELTAMGIEVLFDDRKERPGVMFSDMELIGIPHTIVIGDRSMKEGNFEYKNRRSGEKTAVAMADIVEHVKAQLQ
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OADC_CHRSD
Sequence: MATPSQHDLRNDFRALLASSECYFTASVFDPMSARIAADLGFEVGILGGSVASLQVLAAPDFALITLSEFVEQATRIGRVTRLPVIADADHGYGNALNVMRTITELERAGVAALTIEDTLLPAQYGHKSTDLIPLDEGVGKMRAALEARIDPAMAIIARTNAGQLDDEAAVERVCAYQAAGVDAICLVGVRDFDHLERLAAPLDIPLMLVTYGNPELRDRARLAALGVRVVVNGHAAYFAAIKATYDCLREQRDIAASELNASQLATRYSTLDEYREWARDYMDVKE
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate into pyruvate.  Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
What are the official names of this protein?
Oxaloacetate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
Protein: K2C79_MOUSE
Sequence: MRSSLSRQTFSTKGGFSSNSASGGGGSRMRTSYSSVTMSRGSGGGGGVRSGSSSGGFGSRSLYNLGGKNISVSMACGASSGRALGGFGSGAYVGLGASRQTFGPVCPPGGIQEVTVNQSLLTPLNVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQSQNTGVARSLEPFFENYLSTLRRQLDTKQSERGRLDMELRNVQDNLEDFKNKYEDEINKRTALENEFVLLKKDVDAAYMGRMDLHGKVDSLTQEIDFLQQLFEMELSQVQTNVSDTNVILSMDNNRNLDLDSIIAEVKAQYELIAQKSRAEAESWYQTKYEELQVTAGKHGDSLRDTKNEIAELTRTTQRLQGEVDAAKKQCQQLQTAIAEAEQNGEMALKDAKKKLGDLDTALHQAKEDLARMLREYQDLVSVKLALDMEIATYRKLLESEESRMSGDCPSAISISVTGNSTSVCAGGTAGFGNGLSLGGAGGASKGGFGSSVSYGAAKGGQVSGGTSILRKTTTVKTSSRRY
What are the official names of this protein?
Keratin, type II cytoskeletal 79, Cytokeratin-79, CK-79, Keratin-79, K79, Type-II keratin Kb38.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: MMM1_TALSN
Sequence: MSQHSQYGVPGVPAQSSLSFTQGFLLGQLSVVLLIGAFIKFFIFGEAPAPPSRGLASRTASHHRSYSINQGDNNANNNTNNGSSPRTLREKPSTSNVLRPVPSSATNTRSILRKTYYNAIPTQLSHTKQGRHRIQHSTHQPESLDWFNVLIAQTIAQYRQTAYLLKDSPTSSILDSLSAAINDPQKKPSFIDTIKVTDISLGEEFPIFSNCRVIAVDDSNSDGGRLQALMDVDLSDDNLSLAIETSLILNYPKPRSAVLPVALSVSVVRFSGTLCISLIPASTPQSPSSAPTPDAGNLNMRSLFQHISAELNGTAPNPTATNPSGKKGVPKTNLAFSFLPDYRLDLSVRSLIGSRSRLQDVPKVAQLVEARIQSWFEERVVEPRVQVVGLPDFWPRMGRTGVRPGDDVEAAAAAAAASVSSRSGGGPVEATTLSGSAEEAIIDDSPVRPGLRFRGSATATAGRSDSSFEEIPRASPQTPLDIPGSMPRVVRTP
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: FENR_GEOKA
Sequence: MSVKEDRNVYDVTIIGGGPTGMFAAFYGGLRQMKVKIIESLPQLGGQLAALYPEKYIYDVAGFPKVRAQELVNQLKEQMDLFSPTVCLNESVDTLEKQEDGTFKLVTNQQIHYSKTVIITAGNGAFQPRRLEIESASRYEGKNLHYFINDLGQFSGKRVLVCGGGDSAVDWSLMLEPIAQSVTIVHRRDKFRAHEHSVEQLKKSSVQVKTPFVPVELVGDEHAIRQVILEHVKEGTKETIDVDAVIVNYGFISSLGPIKNWGLDIEKNAIKVNSRMETNIPGVYAAGDICTYDGKIKLIACGFGEAPIAISSAKTYIDPTARMQPAHSTSLF
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: HMOX2_ORYSJ
Sequence: MPLAAAVAASAVVPPRPPPPPPRRARPLRSFTGLILTRDLAALTVARCAPSPPAPAAEAEAEAVAVDEAPPAKPRPRRYPRQYPGEAVGVAEEMRFVAMRLRNPKRTTLKMDDTGAEEEVGDGVSEDASASEEEEEEEDDDDVVEEEEEGAGLEGEWMPSMEGFVKYLVDSKLVFDTVERIVAESTDVAYVYFRKSGLERSARITKDLEWFGGQGIAVPEPSTAGSTYATYLTELAESNAPAFLSHYYNIYFAHTTGGVAIGNKISKKILEGRELEFYKWDSDVELLLKDTREKLNELSKHWSRKDRNLCLKEAAKCFQHLGRIVRLIIL
What is the function of this protein?
Probable inactive heme oxygenase that may play a role in the regulation of phytochrome assembly and photomorphogenesis.
What are the official names of this protein?
Probable inactive heme oxygenase 2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSBU_SYNP2
Sequence: MSRVVSALMGLVLMFGCAFFSVQPQAQALDLSNGFVSAAVLGERVNPADKVLESEYGKKIDLNNASVRLFRELRGFYPTLAKRIIENAPYDSVEDVLNIPDLSEKQLARLEENLERFTVTPPADVFIDGDQRLNTGDY
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: DCD_CUPMC
Sequence: MSIKSDKWIRRMAEQHGMIEPFEPGQVRESDGRKIVSYGTSSYGYDIRCADEFKIFTNINSTIVDPKNFDEKSFVDFKGDVCIIPPNSFALARTMEYFRIPRSVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGCAQVLFFESDEICETSYADRGGKYQGQQGVTLPKT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PURQ_THEAC
Sequence: MKPPKVGILLMEGTNNETEVFFSVRRSGGDPDYVHVSDIAAGRKAISDYDALIVPGGFSAGDYIRAGVIFAARLLAVAGKEIRDFVDSGRPLIGICNGFQVIMEMGLIGKRDELTLTNNESGRFECRYTYITMTSDNPIFRDAFKGKGSFQVPVAHAEGRIAVSGVSVLKRLYENDQVLFKYSDTHGVTDEYPWNPNGSVDSIASLTNEHGNVIGLMPHPERIYYSYQAMYDDARKDQATGKLFYDSLISYLSGVHG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARHL1_HUMAN
Sequence: MEKFKAAMLLGSVGDALGYRNVCKENSTVGMKIQEELQRSGGLDHLVLSPGEWPVSDNTIMHIATAEALTTDYWCLDDLYREMVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLRYWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPLAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRKWSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK
What is the function of this protein?
Required for myofibril assembly and outgrowth of the cardiac chambers in the developing heart (By similarity).  Appears to be catalytically inactive, showing no activity against O-acetyl-ADP-ribose (By similarity).
What are the official names of this protein?
Inactive ADP-ribosyltransferase ARH2, ADP-ribosylhydrolase-like protein 1, [Protein ADP-ribosylarginine] hydrolase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere.
Protein: SSTT_SERP5
Sequence: MQKLLQKITQGSLVKQIMVGLVAGIIVALVSPATASAVGLLGALFVGALKAVAPVLVLVLVMASIANHKHGQKTNIRPILFLYLLGTFAAALVAVVVSFMFPSNLALVAGNAEINPPGGIIEVLKGLLLSVVANPFQALISANYIGILAWAVGLGLALRHSSDTTKSLINDMSHAVTMVVRAVIRCAPLGIFGLVASTLAETGFGALWGYAQLLVVLIGCMLLVALVLNPLIVFWKIRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMELCKKLNLNEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIPVDVPTALLLSVVAAVCACGASGVAGGSLLLIPLACNMFGIPNDVAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAACQAEDQRLADEDPLKVR
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DCUP_SHIDS
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPLEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRFA_ECO24
Sequence: MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNETFAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVRETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGCADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYFDGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHGKNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQSINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHMHAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQIKAEKQDFIKTVIPQWEEQARKNGLLSQ
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: 2AAA_PIG
Sequence: MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA
What is the function of this protein?
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit (By similarity).  Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT (By similarity).  Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis (By similarity).  Together with RACK1 adapter, mediates dephosphorylation of AKT1 at 'Ser-473', preventing AKT1 activation and AKT-mTOR signaling pathway.  Dephosphorylation of AKT1 is essential for regulatory T-cells (Treg) homeostasis and stability (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere. Lateral cell membrane. Cell projection, dendrite. Note=Centromeric localization requires the presence of BUB1.
Protein: ITR1_NICSY
Sequence: MVKLALVVIFLLLASLFQPLTAQSSCPGNKKETWPELIGVPAKFAREIIQKENSKLTNVPSVLNGSPVTKDFRCERVRLFVNVLDFVVQIPRVG
What is the function of this protein?
Stress response.  Inhibits trypsin.  May play a role in the reentering of protoplasts into the cell cycle.
What are the official names of this protein?
Trypsin inhibitor 1, NSTI-I, Trypsin inhibitor I.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I13 (potato type I serine protease inhibitor) family.
What are the subcellular locations of this protein?
Vacuole. Secreted.
Protein: GBA1_PANTR
Sequence: MEFSSPSREECPKPSGRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGTIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ
What is the function of this protein?
Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramides/GlcCers (such as beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine) into free ceramides (such as N-acylsphing-4-enine) and glucose.  Plays a central role in the degradation of complex lipids and the turnover of cellular membranes.  Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation.  Catalyzes the glucosylation of cholesterol, through a transglucosylation reaction where glucose is transferred from GlcCer to cholesterol.  GlcCer containing mono-unsaturated fatty acids (such as beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4-enine) are preferred as glucose donors for cholesterol glucosylation when compared with GlcCer containing same chain length of saturated fatty acids (such as beta-D-glucosyl-N-octadecanoyl-sphing-4-enine).  Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl 3-beta-D-glucoside to ceramide.  Can also hydrolyze cholesteryl 3-beta-D-glucoside producing glucose and cholesterol.  Catalyzes the hydrolysis of galactosylceramides/GalCers (such as beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine), as well as the transfer of galactose between GalCers and cholesterol in vitro, but with lower activity than with GlcCers.  Contrary to GlcCer and GalCer, xylosylceramide/XylCer (such as beta-D-xyosyl-(1<->1')-N-acylsphing-4-enine) is not a good substrate for hydrolysis, however it is a good xylose donor for transxylosylation activity to form cholesteryl 3-beta-D-xyloside.
What are the official names of this protein?
Lysosomal acid glucosylceramidase, Acid beta-glucosidase, Beta-glucocerebrosidase, Cholesterol glucosyltransferase, SGTase, Cholesteryl-beta-glucosidase, D-glucosyl-N-acylsphingosine glucohydrolase, Lysosomal cholesterol glycosyltransferase, Lysosomal galactosylceramidase, Lysosomal glycosylceramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 30 family.
Protein: ATPA_MAIZE
Sequence: MATLRVDEINKILRERIEQYNRKVGIENIGRVVQVGDGIARIIGLGEIMSGELVEFAEGTRGIALNLESKNVGIVLMGDGLMIQEGSFVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEIVASESRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQDVICVYVAIGQRASSVAQVVTTFHEEGAMEYTIVVAEMADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYLGDVFYLHSRLLERAAKLNSLLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELQAFAQFASALDKTSQNQLARGRRLRELLKQSQSNPLPVEEQVATIYTGTRGYLDSLEIEQVKKFLDELRKHLKDTKPQFQEIISSSKTFTEQAETLLKEAIQEQLERFSLQEQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SYA_METST
Sequence: MTYELEQLGYKKQVCQKCGNTFWSIRERATCGDAPCDEYEFIGNPVTDKQYDLMGIQKKFKGFFKDHGHTPINRYPVLAKRWRNDVFLVGASIYDFQPWVTSGMVRPPANPLVVAQPSIRLNDVDNVGRTGRHMTCFTMGAHHAFNTDETPIYWKNETLRYCHEFLVSIGINPEEITYIESWWKGGGNEGPSFEICAHGVELATLVFIQYATTKDGLKEIPLKIVDTGYGLERIAWVSQGTPTAYDATFGSVIDKLTDISGVELNTEILSENARIAGMMDIEDISDLKLLRKKVADKLSLDPDMLKKTTAPMEAIYIVADHTRCLSFMLADGIIPSNVKEGYLARLVLRRTVKYMNELGLNESLSDIMKMQVDYLSKTYPEIKDNKDHIINITDLEEERYHTTLTKGKNLVKRSIKTLKKQNKKSFPTDMLINFYDSHGIPPETVEAISKENAFDANIPDNFYTQIAAAHEEEEEEEIEEMELNFPKTKLSFYDDLKQRTFTAKVLGVVDSNKIILNQTIYYPEGGGQPSDIGTITRVNGEVLNITYAQKVDGIVLHHVAKEDESKLDNIVGEEITGEIDSKRRDLLTRNHTATHLVIASAREVLGKHIWQAGAQKGLDKTRIDLSHYKRISHEEVQEIERLANKRVQENHPVNIQWYDRTDAEVKYGFKLYQGGIVPGKNIRVVEIPGIDVQACAGTHCEKTGDIGVIKLLRTERVQDGVERLEYAVSDSGIKKIQDDDDIIRNSSDVFGVDAEQLPRTCKRFFNEWKEQQKRIKSLEKQLAQVKIFSLENEIANINGYNVITEVLDVDNNQLREIAINLVEKEEVADIAILINNNGNIVASSNNKILEKGMKMGDVVNDIGKFLGGRGGGKPTLAQGAKMTDLSRKDEAFESVKEQIRSWN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_SHEAM
Sequence: MSVTNKVLVLKVGGALLQCEMGMARLMDTARQLLEKGEQVVLVHGGGCLVDEQLKANGMETVKLDGLRVTPAEQMPIIAGALAGTSNKLLQGAAAKAGVVSMGMSLCDANMVTAVIKDERLGMVGEVSPKDAKALEFILAQGWLPIISSIAMGEDGELLNVNADQAASVLAKLLGGKLVLLSDVSGVLDGKGKLIPSLNSQEIDELVKLGVIEKGMKVKVEAALEVAQWLGQPVQVASWRDSGQMAALIKGEAVGTQIQPQE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.