PharMolix/UniProtQA huggingface dataset:
Protein: COBL8_ARATH
Sequence: MGLTRNFILWILLSSLFTAIQLTSSQRNTPPPRSKDADLCNGVFVSYTYLTGTKIKPNDTKNQPYRFESEITVLNNGRDELKSWQVFVKFAHREILVSATNAVLSDGSSLPASVENGTIFAGFPSADLKTAIMTAGDVTQMEARVELVGTQFGVAPPSVPLPKNITLVNDGWSCPKPTQQGSNVLQVCCTPNPNITTSKIGQKFLPRQEGDLTIMYDVTRAYQSSYSAQVTIENHNLLGRLDNWDLSFMWMKDEFLFSTKGAYPSVVDSSDCITGPQAKYYKDLDFSNVMSCARRPHIIDLPLTKYNDTNVGRIPYCCRNGTILPRSMDPEKSKSVFQIEVYKMPPDLNISSITPPQSWQIKGNLNPDYKCGPPLRVSSSQFPDTSGLPSNKSAFASWQVVCNITQPTPPKCCVSFSSYFNDSVIPCKTCACGGCSSDRVARTCSTTSPALPLPYQALLIPFDNRTKLTNAWAVLKNRKVPDPLPCGDNCGVSINWHLATDYRGGWTARVTLFNWGDTDFVDWFTAVELRNAAPGFQKAYSFNGSIIAVNGKNTTVLMEGLPGLNYLLAEKDGKNPSEDFRIPGKQQSVISFTKKLTPGIKVGSKDGFPTKVLFNGQECSLPSVLPTSNSHRKHVSTFLLILTPFLALLFLRI
What are the official names of this protein?
COBRA-like protein 8.
What is the protein family that this protein belongs to?
Belongs to the COBRA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CLPB2_PARMW
Sequence: MTGTPASRGSLTHEPDRFSDPAWELLLAGQDMARRWRHDQLDVEHLIQVLFSDSSFRRWVEPLPLRSDDLLDRLEDVLADQPPARGDQLFIGEDLEQLLETADQVRGRWGDRSIDVPQLIVAVGADPRIGAELFAAQGLAVDRLESLLRQPSVSPAPAPPPVPTAASAPAPTPRSAPAPRVMAPEPEPMVELEREPSALEAYGRDLTEEAEAGSLDPVIGRDSEIRNLIKVLSRRSKNNPVLIGEPGVGKTAIAELLAQRIVAGEVPDSLQGLRLIALDLGALIAGAKFRGQFEERLRSVLEEVSRSDSGVVLFIDELHTVVGSDRSSTDAGSLLKPALARGDLRCIGATTPEEYRRTVEKDPALNRRFQQVLIREPDLELSLEILRGLRERYELHHGVTITDEAIQTANRLADRYISDRCLPDKAIDLIDEAAAQLKIEVTSKPQVVEEAEADLRRVELALLAAEEAPEEERIQLQRQRLEVSSRLDDLRRRWQEERTQLEELGQLLQQDEDLRHAIAEAEREGALEEAARLQYDQLHTVQQRREALEASQAEAQSAGTALLREQVEAGDIADLVARWTGIPVQRLLAGERRKLLALESHLSERVIGQVEAVAAVAAAIRRARAGMKDPRRPVGSFLFLGPTGVGKTELAKALATSLFDEEEALVRLDMSEFMERNASARLIGAPPGYVGYEEGGQLTEAVRRRPYAVLLLDEVEKAHPDVFNLLLQVLDDGRLTDSQGLTVDFRHTVVVMTSNLASPVILEHARSGSSDDAQLQQQVDAALSSQFRPEFLNRIDEVIRFRPLKVKDLVRIVRLQLADLSTLMAEQGLSLEVDDAVADSLARQGHEPEYGARPLRRVLRRQLENPLATQLLEERFRSAHGIRVRCGTDDGASLEFEPLE
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB 2.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_CLOPE
Sequence: MKKRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGRVKTLHPLVHAGILAIRDNKEHMKTLEEREINTIDYVVVNLYPFFEKVREDLSFEEKVEFIDIGGPTMLRAAAKNFKDVVVLSDKKDYEKVMNEIKENNCVSFKLRKTLAGKVFNLMSAYDAAISNFLLEGEEEYPEYLSVSYKKIQDLRYGENPHQGAAYYSSTEFDGAMNSFEILNGKALSYNNIKDLDIAWKVACEFEETACCALKHNTPCGVAVGENSKEVYLKAYDADPVSIFGGIVAINRKIDKATAEEMVKIFLEVVAAPDFDEDALEVLRTKKNLRVIKCKNTPQAKNYMVTVDGGILVQGEDNKLANEYKVVTEKEPTEMELRDMIFGMKVVKYVKSNAIVVVKDGVATGIGGGQVNRIWATKEALERGKGGAVLASDAFFPFRDCVDEAAKNGIKAIIQPGGSIRDEESIEACNEHGISMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: LDN1_ODOLI
Sequence: MFTLKKSLLLLFFLGTINLSLCQEERNADEEERRDERNVEVEKRILPFVAGVAAEMMQHVYCAASKKC
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Lividin-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DIAA_ECO24
Sequence: MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDV
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: NST1_PHANO
Sequence: MDWTGARARTSWGKRPQTAALGLAATFRHLNTDDHRPIEQTTQTPYSLHRPLPPPSGEPATDTPTHSSCPAPPIAVPSSLLLPRTTHPSSRSSHICACHTPVTARHSPNRLCPVSLPTPTPRSMAQGTKAPAAAMPPNSSVLNMPALNAVNRKKQKRREKEAAKKAAQDPSPPATLRNGVSSGSTHLPANAAHTRQPAPHYDDPELDDPQYDDEDDADFYSDEEAEHYEHAYGTNGHYQQGYAHAPIPSSSKKPRKKKKGAAAHPPHAYTQHVAPRHSPAPNHSMVTSGSKSIWNTSTVEERERIREFWLSLGEDERKSLVKIEKEAVLRKMKEQQKHSCSCSVCGRKRTAIEEELEVLYDAYYEELEQYAHLQQDVGRFLPDANFGHVRSAPHPRPLMTTHPPPGPYDDEEEDEYSGEDDEEDIFKYLPPPDAADFLRFGSSLTVKGGILTVADDLLKNDGKKFIEMMEQLAERRMQREEEANFHAHPSMHRYNSAHNHAPQPEEEEYDDEVDEEEGFEDEDYEEDDEDEDEAMTEEQRMEEGRRMFQIFAARMFEQRVLQAYREKVAAERQKRLLEELEEENEKKDQKEAKKAKEAQKRKEKKEKQRQIKAEEKAKKDAELAAKEAELKAAEEKRLEEQRKKREEQRKKKEAERKAQEEEKQRKEAERQKRLQEERDRQQELERKAREQKALEKKVKDDAKRKERDRAGSQGEGGSGRRRPTTTASARSVKVCRSPHGILSSFVPKAPTPSRPRQTSRQGSHGSSPKTPQVAPGTSKSMSPTSQAQGNMMPKSILTKPANSQHAGHHPLGQPSSPMPPIGPPPGLSGPPGLSMGLPPGLNGFPGPGSMLPNMMSPRPGMPFFPQPPVPQAFRGFPPPGMAGPRGFPMDGPPGLGPMPGFAGPNQAPPFGMGPPTQHSRQGSGSFASMDVPISAPSVQPIHRPAPIQRPSSVKPHDSNKHGQDSDVDELADHLGSKALLDEEDVPEIPDRRSSVQQHGSMRSMPIGFGFPDAPNSHQSTAFNGFGSANTASIWGTPPSQAFSSAAGPWGNSPTSGFFTNPLTMSSPRVSDHRAPNEPRLVWLRRVICTVCKMLSSRHAGPDGFIDANEVQQQLDAFRDPREPVVTQEELKEACDIIDGTHNNGGGSLEYKNLGDGRLSHIKFVDTTGPPPALGEIGSPIPSHSLPVAGFGGRFPGLGPQGF
What is the function of this protein?
May act as a negative regulator of salt tolerance.
What are the official names of this protein?
Stress response protein NST1.
What is the protein family that this protein belongs to?
Belongs to the NST1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUX1_HUMAN
Sequence: MLCVAGARLKRELDATATVLANRQDESEQSRKRLIEQSREFKKNTPEDLRKQVAPLLKSFQGEIDALSKRSKEAEAAFLNVYKRLIDVPDPVPALDLGQQLQLKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKNQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGSARRKGKDQPESRRPGSLPAPPPSQLPRNPGEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSMIFSTGPYSTNSISSQSPLQQSPDVNGMAPSPSQSESAGSVSEGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQRENPGQSLNRLFQEVPKRRNGSEGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPAQPSSASGSGNSDDAIRSILQQARREMEAQQAALDPALKQAPLSQSDITILTPKLLSTSPMPTVSSYPPLAISLKKPSAAPEAGASALPNPPALKKEAQDAPGLDPQGAADCAQGVLRQVKNEVGRSGAWKDHWWSAVQPERRNAASSEEAKAEETGGGKEKGSGGSGGGSQPRAERSQLQGPSSSEYWKEWPSAESPYSQSSELSLTGASRSETPQNSPLPSSPIVPMSKPTKPSVPPLTPEQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLNGELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPPIEASKDSKPPEPSDPPASDSQPTTPLPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGTEYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQAGASDSPSARSGRAAPSSEGDSCDGVEATEGPGSADTEEPKSQGEAEREEVPRPAEQTEPPPSGTPGPDDARDDDHEGGPVEGPGPLPSPASATATAAPAAPEDAATSAAAAPGEGPAAPSSAPPPSNSSSSSAPRRPSSLQSLFGLPEAAGARDSRDNPLRKKKAANLNSIIHRLEKAASREEPIEWEF
What is the function of this protein?
Plays a role in cell cycle progression, in particular at the G1/S transition.  As cells progress into S phase, a fraction of CUX1 molecules is proteolytically processed into N-terminally truncated proteins of 110 kDa.  While CUX1 only transiently binds to DNA and carries the CCAAT-displacement activity, CDP/Cux p110 makes a stable interaction with DNA and stimulates expression of genes such as POLA1.
What are the official names of this protein?
Homeobox protein cut-like 1, CCAAT displacement protein, CDP, CDP/Cux p200, Homeobox protein cux-1.
What is the protein family that this protein belongs to?
Belongs to the CUT homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCEA_PAELA
Sequence: LQYRAADTNAADNQIKPSFNIKNNGTSAVDLSTLKIRYYFTKDGSAAVNGWIDWAQLGGSNIQISFGNHTGTNSDTYVELSFSSEAGSIAAGGQSGETQLRMSKTDWSNFNEANDYSFDGTKTAFADWDRVVLYQNGQIVWGTAP
What are the official names of this protein?
Uncharacterized protein in celA 5'region.
Protein: YCF4_CRUWA
Sequence: MSWRSESIWIEFITGSRKTSNFCWAFILFLGSLGFLLVGTSSYLGRNVISLFPSQQIIFFPQGIVMSFYGIAGLFISCYLWCTILWNVGSGYDLFDRKEGIVRIFRWGFPGKSRRIFLRFFMKDIQSIRIEVKEGVSARRVLYMEIRGQGAIPLIRTDENFTTREIEQKAAELAYFLRVPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HIS6_ACIBT
Sequence: MLAKRIIPCLDVDNGRVVKGVQFLDIRDAGDPVEVARRYNEQGADEITFLDITATHHGRDTTYRTVERMAETVFVPLTVGGGVRKVEDIRALLNAGADKVSINSAAVFNPEFVQEASQHFGAQCIVVAIDAKKTGDNKWEIFTHGGRKPTGIDAIEWAVKMADYGAGELLITSMDADGTKAGYDIALMRAINDRVTIPTIASGGVGNLQHLADGILQGGADAVLAASIFHFGQYTIPEAKQYLAEQGIEMRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNPEP_PLAF7
Sequence: MDKKAREYAQDALKFIQRSGSNFLACKNLKERLENNGFINLSEGETWNLNKNEGYVLCKENRNICGFFVGKNFNIDTGSILISIGHIDSCALKISPNNNVIKKKIHQINVECYGSGLWHTWFDRSLGLSGQVLYKKGNKLVEKLIQINKSVLFLPSLAIHLQNRTRYDFSVKINYENHIKPIISTTLFNQLNKCKRNNVHHDTILTTDTKFSHKENSQNKRDDQMCHSFNDKDVSNHNLDKNTIEHLTNQQNEEKNKHTKDNPNSKDIVEHINTDNSYPLLYLLSKELNCKEEDILDFELCLMDTQEPCFTGVYEEFIEGARFDNLLGSFCVFEGFIELVNSIKNHTSNENTNHTNNITNDINDNIHNNLYISIGYDHEEIGSLSEVGARSYCTKNFIDRIISSVFKKEIHEKNLSVQEIYGNLVNRSFILNVDMAHCSHPNYPETVQDNHQLFFHEGIAIKYNTNKNYVTSPLHASLIKRTFELYYNKYKQQIKYQNFMVKNDTPCGSTVGSMVAANLSMPGIDIGIPQLAMHSIREIAAVHDVFFLIKGVFAFYTYYNQVLSTCVHDK
What is the function of this protein?
Aminopeptidase which specifically catalyzes the removal of glutamic acid or aspartic acid residues from the N-terminus of peptides (PubMed:17720817, PubMed:17895246, PubMed:22709581).  May play a role in the final step of host hemoglobin catabolism, by cleaving hemoglobin-derived oligopeptides in the cytoplasm (Probable).
What are the official names of this protein?
Aspartyl aminopeptidase, M18 aspartyl aminopeptidase, PfM18AAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
Protein: GLPE_SALTI
Sequence: MEQFECITVEEAYQKLHQGAAVLVDIRDPQSYAMGHAPQAFHLTNDTLGAFMREHGFDTAVMVMCYHGNSSKGAAQYLLQQGYDAVYSIDGGFEAWHRRFPADVANGA
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3H4_ORYSJ
Sequence: MAEAEEKRVGVGEARAPLAVEALRGKIVEKVKGNRVTLIVGDTGCGKSSMVPQFLLEENMEPILCTQPRRFAVVAIAQMIAESRNCQVGEEVGYHIGHSNVSNLNSKRSRIVFKTAGVVLEQMRDKGIAALNYKVIILDEIHERSVESDLVLACVKQFMMKKNDLRLILMSATADITRYKDYFRDLGRGERVEVIAIPSSPRSSIFQRKVLYLEQIVDILKMDSESLSTKYCSGPNTAADAGLKPDVYELIHRLLLHIHQNEPDIGKSILVFLPTYYALEQQWIRLLSASSMFKVHILHRSIDTDEALQTMKVSKSCRKVILATNIAESSVTIPGVAYVIDSCRSLQVYWDPIRKTDSAELVWVSKSQAEQRKGRTGRTCDGQIYRLVTGPFYNSLTDHEYPAILRLSLREQVLMICCAESRAMNDPHVLLQKVLDPPDSDVVEDALESLVQIRALDKPTSPRGRHEPTFYGCLLNSLPLSFDASVLALKFGDTGSICEGILISIMLDIQPLPIVQPFGHQQLCKMYRNNYFEEEGIDLQTGKKEAALVGNLCAFQFWQRMFKDKYRLDCLINVVNTHEPKASNGFVAKPEDEWCAFHNLVPTALNYISEIYDDIMGTLHRFRPSFLVKINPPMYLQPSEFHHMCLRHEVLELENVNSLPLEAENSHLDSHRRCAATPYVSPADFGTTTVVKTLKTLIKEMKTQSAADRVTYRELVHGYVQPALENEMCVFFLNGSCNRGDTCHFSHSSRAPRPICKFFLTLQGCRNGNSCSFSHDSGSLVSSSITSGICSQENRATSVCCKRLLPAAGDGHILVMNDKSLQFACKLCNYYDPTKIIACTPGPHSFESDSVTKGLKILQNLADPSYLFIGGEHKLSVPWTKLSRVFWFADIDSNESISEQVVLQKFFQHIAIKTLSEKMSDLQVIVIMNNAKFVQLQVERLARECFLFLGESFMFDEATLGWFSDTPNYPRGMQVSAPVAYIFSMHPPTGIQFGDYASELRKVLYSN
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 4, OsC3H4.
Protein: FBK89_ARATH
Sequence: MERLVSGETTTSSNMKKKKKKVSSTTNPSLPDDLVLVIIARVSILYYPILSLVSKSFRSLLASPELYKVRSLLGRRESRLYVCINMYSYKNGPSWFTLCRKPDRTTTSSNKEEDRSSGYVLARIPIPHSPLTQRYSLAAVGSNIYNIGVTRYHHLTSSSVWVLDCRSHTWRQAPSLPVELFRVSVSVLDQKIYVAGLHQEDGSDSLKNSVTVLDTETQVSDRVAIPCSVSQGKEIFISTSVGGKVNLVTGRKVVDYNPVEGSWEEVGDTMCEFMFSKCFCVVGNVLYSCAIDRVFRWYDTEVRTWRNLECLIGGRLPKLSPRAFVSLADYGGKLAVFWNQGVGDWQMLWCAVIALERRNTCEILGNVEWSDHVLHVPKIRSYYNALSATL
What are the official names of this protein?
F-box/kelch-repeat protein At4g25710.
Protein: NODP_RHISB
Sequence: MSLANLRRLEAEAIHVLREVVATFSNPVVLYSIGKDSSVLLHLAMKAFFPAKPPFPFLHVDTTWKFREMIAFRDRMARELGFNLLVHTNQDGVDQGIGPFTHGSNLHTHVMKTMALRQALETYGFDAALAGARRDEEKSRAKERMFSIRNAQHGWDPKRQRPEMWKTYNTRVGAGETMRVFPLSNWTEFDIWQYILQENIPIVPLYFAARRPVVRRDGMLIMVDDERMPIEPGEEVMDRMVRFRTLGCYPLTGAIDSEAATVPDILREMLTVRTSERLSRLIDTDEAGAMEKKKREGYF
What is the function of this protein?
Proposed to provide activated sulfate for transfer to nod factor.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Nodulation protein P, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: CH10_LACAC
Sequence: MLQPIGDRVIVKVKEEEEKTVGGIVLASNAKQKPTEGEVVAVGEGAYTSNGDKLPMVVKKGDVVLYDKYSGTNVEYEGEKYLVLHEKDILAIEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILRL1_HUMAN
Sequence: MGFWILAILTILMYSTAAKFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATLLWRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQITHNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVRYQMPVPSKIPRKASSLTPLAAQKQ
What is the function of this protein?
Inhibits IL-33 signaling.
What are the official names of this protein?
Interleukin-1 receptor-like 1, Protein ST2.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
[Isoform C]: Cell membrane. SUBCELLULAR LOCATION: [Isoform B]: Secreted. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: A1I3_LOXSP
Sequence: WIMGHMVNAIGQIDEFVNLGANSIETDVSFDDSANPQYTYHGVPCDCGRSCLKWENYNDFLKGLRSATTPGNSKYQSKLVLVVFDLKTGSLYDNQANEAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFTDTLTQEGHPELLDKVGFDFSGNDAIGDVANAYKKAGVTGHVWQSDGITNCLLRGLTRVREAVANRDSGKGYINKVYYWTVDKRASTRDALDAGVDGVMTNYPDVITDVMNEAAYKNKFRLATYEDNPWETFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LspaSicTox-alphaIA2iii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KDGT_ENT38
Sequence: MKIKATIERIPGGMMLVPLVLGAILNTLAPNTGAYFGGFTKGMISGTVPILAVWFFCIGASINLRATGTVLRKSGTLVLTKIAVAWVVAMGCAMFIPENGIQTGFFAGLSVLAIVSAMDMTNGGLYASLMNQYGTKEESGAFVLMSLESGPLVTMLILGSAGLASFEPHHFVGAVLPFLIGFALGNLDTDLRDFFSKATPVLIPFFGFALGNTINLNVIMDTGLLGIVLGVAVIIITGIPLIIADRVIGGGNGTAGVAASSAAGAAVANPMIIAQINPSFEPVAASATALVAASVIVTAILVPIITALYAKRYGNIPKADVEPQPVESLHH
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMD_VIBC3
Sequence: MARFFQPKKHSTLDTKHQPVTIERLDHQGSGLAFLHKKPLFVDGALPGEEVLIQLTENKSKYARGQLIKVLKPSAERVAPFCAHYAQCGGCDLQHLDRAGQIHHKQQALSQLMVKFAGQSLALSAPVCSDDQGYRRRARLSLMWDKKTQQLQLGFRRKQSKAIVNVTDCPVLEPSLNALLPDLNALLSEWSQPERLGHVELVKGDNTRVLVLRHLGALIEQDQQRLTDFASQNQLTLYLMLEAGELQHVQGEAPYCEETGSRLSFLPSHFIQVNRAVNQHMVAQALNWLEVSPQEHVLDLFCGLGNFTLPLAKQAQAVVGVEGVDEMVQHATHNAKLNQINNVAFYQANLEQDMTSASWAQQKFAKVLLDPARAGAEGIVDQLSALGAKRVVYVSCNPATLARDSQSLLSQGFRLEKLGMLDMFPHTSHLESMALFVKKG
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: LGT_STRA5
Sequence: MINPVAIRLGPFSIRWYAICIVSGMLLAVYLAMKEAPRKNIKSDDILDFILMAFPLSIVGARIYYVIFEWAYYSKHPVEIIAIWNGGIAIYGGLITGAILLVIFSYRRLINPIDFLDIAAPGVMIAQAIGRWGNFINQEAYGRAVKNLNYVPNFIKNQMYIDGAYRVPTFLYESLWNFLGFVIIMSIRHRPRTLKQGEVACFYLVWYGCGRFIIEGMRTDSLYLAGLRVSQWLSVILVIIGIVMIIYRRREQHISYY
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TGFR1_BOVIN
Sequence: MEAAAATPRPRLFLLMLAAAATLVPEATPLQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSITTTYCCNQDHCNKIELPTVGKPSSGLGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEVARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM
What is the function of this protein?
Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3.  Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis.  The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2.  Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4.  The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes.  This constitutes the canonical SMAD-dependent TGF-beta signaling cascade.  Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.  For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis.  Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation (By similarity).
What are the official names of this protein?
TGF-beta receptor type-1, TGFR-1, TGF-beta type I receptor, Transforming growth factor-beta receptor type I, TGF-beta receptor type I, TbetaR-I.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Membrane raft. Cell surface.