PharMolix/UniProtQA huggingface dataset:
Protein: RIMO_CELJU
Sequence: MTTSGCNPMKSSSTSNPTIGFVSLGCPKNLVDSERILTQLRMEGYNIVPSYNDADMVIVNTCGFIDSAVQESLGAIGEALNENGKVLVTGCLGAKKDEIIQVHPNVLGITGAHAYEEVLAQVHEHLPPSQTHNPFTDLVPPQGIKLTPRHYAYLKISEGCNHSCSFCIIPDMRGKLVSRPIGQVMGEAERLVKAGVKELLVISQDTSAYGVDIKHRTDFWDGRPLKTDMYQLAAALGELGVWVRLHYVYPYPHVDNVIPLMAQGKVLPYLDIPFQHASPTLLRKMRRPGQVEKTLERIKNWREQVPNLTLRSTFIVGFPGETEADFEELLGFLEEAQLDRVGCFQYSPVEGAKANELPDPVLDEIKQARYDRFMQLQQRISTERLKQKVGQTLPVLIDEVDDEGAIGRSYADAPEIDGCVYLNGDIQVKPGDIVNVQIEHSDEYDLWGTRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZBT39_HUMAN
Sequence: MGMRIKLQSTNHPNNLLKELNKCRLSETMCDVTIVVGSRSFPAHKAVLACAAGYFQNLFLNTGLDAARTYVVDFITPANFEKVLSFVYTSELFTDLINVGVIYEVAERLGMEDLLQACHSTFPDLESTARAKPLTSTSESHSGTLSCPSAEPAHPLGELRGGGDYLGADRNYVLPSDAGGSYKEEEKNVASDANHSLHLPQPPPPPPKTEDHDTPAPFTSIPSMMTQPLLGTVSTGIQTSTSSCQPYKVQSNGDFSKNSFLTPDNAVDITTGTNSCLSNSEHSKDPGFGQMDELQLEDLGDDDLQFEDPAEDIGTTEEVIELSDDSEDELAFGENDNRENKAMPCQVCKKVLEPNIQLIRQHARDHVDLLTGNCKVCETHFQDRNSRVTHVLSHIGIFLFSCDMCETKFFTQWQLTLHRRDGIFENNIIVHPNDPLPGKLGLFSGAASPELKCAACGKVLAKDFHVVRGHILDHLNLKGQACSVCDQRHLNLCSLMWHTLSHLGISVFSCSVCANSFVDWHLLEKHMAVHQSLEDALFHCRLCSQSFKSEAAYRYHVSQHKCNSGLDARPGFGLQHPALQKRKLPAEEFLGEELALQGQPGNSKYSCKVCGKRFAHTSEFNYHRRIHTGEKPYQCKVCHKFFRGRSTIKCHLKTHSGALMYRCTVCGHYSSTLNLMSKHVGVHKGSLPPDFTIEQTFMYIIHSKEADKNPDS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VG49_BPMD2
Sequence: MSYEDPFASAPVDTAPAEEAQQQTPTESPWDPPAQQTQTVEVRPAPADALSITFKGDGSYSAPWLVPKYASVTEALVDLGVDPDEVAKLGQGQKWFALMDRVTKMADHFANLGGGSKPNSGGGGSGGGGQQHQSRAPQQAQEAPGGEERFCKHGKMEFKSGVSKAGNTYALFSCTAPRNEQCPAQYPSKKNG
What are the official names of this protein?
Gene 49 protein, Gp49.
Protein: TAL_KOSOT
Sequence: MRIFLDTANIEEIKKAVAWGVIDGVTTNPTLIAREKAPFTERIKEICETVKGPVSAEVVALDYEGMVKEARDLAMLDEHVVIKIPMTPEGIKAVKTLSSEGIKTNVTLVFSAVQALLAAKAGATYVSPFIGRVDDISSDGLRLVEDIVAIFSNYGFQTNVLAASIRHPMHVLELATIGVDIVTMPFNVLEKLFHHPLTDKGIERFLNDWEEYRKGTGL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRAF2_HUMAN
Sequence: MSEVRLPPLRALDDFVLGSARLAAPDPCDPQRWCHRVINNLLYYQTNYLLCFGIGLALAGYVRPLHTLLSALVVAVALGVLVWAAETRAAVRRCRRSHPAACLAAVLAVGLLVLWVAGGACTFLFSIAGPVLLILVHASLRLRNLKNKIENKIESIGLKRTPMGLLLEALGQEQEAGS
What is the function of this protein?
May be involved in ER/Golgi transport and vesicular traffic.  Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis.
What are the official names of this protein?
PRA1 family protein 2.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: CH60_METPP
Sequence: MAAKDVVFGGEARARMVEGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKTSDNAGDGTTTATVLAQAIVREGMKYVAAGMNPMDLKRGIDKAVVSLVEQLKKQSKPTTTSKEIAQVGTISANSDDDVGQIIASAMDKVGKEGVITVEDGKSLNNELDVVEGMQFDRGYLSPYFINNPEKQSAVLDNPFVLLYDKKISNIRDLLPTLEQVAKSGRPLLIIAEEVEGEALATLVVNTIRGILKVVAVKAPGFGDRRKAMLEDIAILTGGKVIAEEVGLTLEKVTLADLGQAKRVEVGKENTTIIDGAGAAGDIEARVKQVRVQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALLRAKQAAGAIKGDNADQDAGIKLILRAIEEPLRIIVTNAGDEASVVVNAVLAGKGNYGYNAANGTYGDMIEMGILDPTKVTRTALQNAASVAALMLTTEAMVAESPKDDAPAGGMPGGMGGMGGMGMDM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTPR_EUGGR
Sequence: MAEKENVHPQVISSFPTPSKALKLSEKSSLKDVQTDNAAVPLVVDETSYPEPTCEFYGGLLGPQLPEAERFVLDPALVEEYRHKKPPFGFNGLGEVVYLRTYAREKDNGQSEVWLDTVQRVVTGTFEVLQHHVVNKLHCHWDAQKAKERSEDMFRRIFEMKFLPPGRGLWAMGSPICRKKGFAAALNNCAFVSTATLEKDRVGPFLFLMDASMLGVGVGFDNAGAGSFTVPGPDDTQPTYKFMIPDKREGWVESLKRLLKAHFCHTADVEFDYSKIREMGTKLKTFGGTSSGPGPLINLHKSIRKILVGEKGKPISVTCITDIMNLIGVCTVAGNIRRSAEIAFGEADCKEFLDLKSYETNPHRVEYGWASNNSIFAKVGMDYSDACERVRTNGEPGFAWLSNMQAFSRMNGKPDYRDQRVLGGNPCLEQSLESMELCCLVETFPDKHETLEDFKRTLYSALLYAKTVTLLPLHWRESNEIMLRNRRIGCSVSGIAQFITNRGLHELKTWLEEGYDILHQYDCQISEWLCIRQSIKLTSVKPSGTISLVAGATPGVHYPESCYYTRRLRMARDSPLLERLIKAGYHVEPCCVAPDVTAIVEFPVAAGNSIRTTRDITMWEQLSLAAFMQRYWADNQVSATITFDPETEGLHLNQALQYFQYQLKGISFLPRYPMGAFKQMPYEAITKEQYEEAIRKVKEDVSLSSANAIAETVEENQQTFCDNDRCIKL
What are the official names of this protein?
Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase, RTPR.
What is the protein family that this protein belongs to?
Belongs to the class II ribonucleoside-triphosphate reductase family.
Protein: RL34_SULTO
Sequence: MPNPHYRSTSYRKIHTKLPSGKSTIHYERRKNNRAVCAICKKPLQGVKTNLLYKYSKTEKRPERMYGGYICYKCLENLIKQTLRGSS
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: RL35_RICB8
Sequence: MPKLKTKSAVKKRFKLTASGKVVASQAGKKHFMRRRTKAQIRNLRGTTILCDQDGYNIKKYFLPYGTN
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL18_BACLD
Sequence: MITKTSKNAARLKRHARVRAKLSGTPERPRLNVFRSNKHIYAQVIDDVNGVTLVSASTLDKDFNAENGSDTAAAAKVGELVAKRASEKGITNVVFDRGGYLYHGRVKALADAAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PUR7_PORGI
Sequence: MKETLARTDFRLPGQKAVYHGKVRDVYTLENDLLVMIATDRISAFDVVLPAGIPYKGQVLNQIAAHYLDATRDIVPNWKIATPDPMVTIGHRCEPFKVEMVIRGYITGSAWRAYAAGERVLCGLPLPEGMRENQRFEHPIITPTTKADEGHDENISRQEIIAQGLVSKEDYEQIERYTYALFERGTQMAAEKGLILVDTKYEFGKKDGKIYLIDEIHTPDSSRYFYAEGYQERFERGEAQKQLSKEFVRQWLIENGFQGKPGQQIPKMTEAYCDSVSERYIELYERVVGKPFEKADLSNLAERIEKNITEYLR
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: APT_DICNV
Sequence: MNMDWKNLIINIPDYPKAGINFKDITPLLANGAGFKAAIEEMAMICERQNAIPDVLACPEARGFIFAAALAHRLGIGFIPLRKPHKLPREVAHINYGLEYGEDCLEVHKQDIKKGMRIMMVDDVLATGGTMHACMNLLQSLGAEIIGAMFLLELTALKGREKLGTAAVYSLIQD
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPC1_LAMBD
Sequence: MSTKKKPLTQEQLEDARRLKAIYEKKKNELGLSQESVADKMGMGQSGVGALFNGINALNAYNAALLAKILKVSVEEFSPSIAREIYEMYEAVSMQPSLRSEYEYPVFSHVQAGMFSPELRTFTKGDAERWVSTTKKASDSAFWLEVEGNSMTAPTGSKPSFPDGMLILVDPEQAVEPGDFCIARLGGDEFTFKKLIRDSGQVFLQPLNPQYPMIPCNESCSVVGKVIASQWPEETFG
What is the function of this protein?
Acts as a transcriptional repressor that allows virus to establish and maintain latency.  Prevents both the viral DNA replication and the exit programs.  Clamps the two operator OL (operator left made of OL1, OL2 and OL3 sites) and OR (operator right made of OR1, OR2 and OR3 sites) together by binding to them and arranging the intervening DNA in a loop.  This step allows repression of lytic pR and pL promoters by binding to OL1, OL2, OR1 and OR2 simultaneously.  The binding of cI on OR2 additionally activates the transcription of the cI gene thereby mediating an autoregulatory function to maintain the latent state.  Once cI is present in sufficient amount, it can repress its own transcription by binding to OL3 and OR3.
What are the official names of this protein?
Repressor protein cI.
Protein: RS9_YERP3
Sequence: MAENQYYGTGRRKSSSARVFLKPGSGKIVINQRSLEVYFGRETARMVVNQPLELVDMVTKFDMYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAGFVTRDAREVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: MINC_BURL3
Sequence: MSLKKSPFFELRSGSVDTLLFTVKTTDLDALRTELVKRFEATPEFFADDVVAIDVRRLADGERVALADIRQMLNDVRMRPVGVVALATQGWAGEAGLPLLEARDRRTPAAKHADEAEPAPAPVVEAAAAPAAESAQEPAPTLLHAGGRTLVIDRPLRSGQQIYAKGDLVVLAPVSHGAEIIAEGNIHIYAPLRGRALAGVHGNHDARIFCTCLEPELISIAGIYRTTENPLPAEVLGKSVQIRLEEEKLMIEPLRLT
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: GLGC_BIFLS
Sequence: MAKNPKILSIVLAGGEGTRLMPLTRDRAKPAVPFGGVYRLIDFPLSNLVNSGYRQVVVLTQYKSHSLDRHISQVWRFSPLLGSYVSPVPAQQRLGKHWYLGSADAIYQTINIIEDVQPDIVVIVGADHVYRMDFEQMVQQHIESGAEFTVAGIRQPIEESNQFGVIEVDHDHPNMIKNFQEKPANTTGLPDNPNQILASMGNYVANTKALFEALSLDEKAADTKHDMGGDIAPYFASRNEAGVYDFNSNEIPGSTATDHAYWRDVGTIKQFYDAHMDLIAYVPEFNLYNQDWPIYTMSGNLPPAKFVHAGRDRLGHATDSIVSPGVIVSGGEVHHSVLSPNVRIHSWAQIVDSVLFDGVIINRRARVYKAILDKNVVLTENSTVGIDTEHDLARGFTVTPDGITVVPKNTIVDD
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: PURT_KLEP3
Sequence: MTVLGTALRPAATKVMLLGSGELGKEVAIECQRLGIETIAVDRYPDAPAMQVAHRAHVINMLHGESLRALIEQEKPDYIVPEIEAIATDTLVELEQAGQKVVPTARAAKLTMNREGIRRLAAEELQLPTSSYRFADSEEGFRAAVTDIGLPCIVKPVMSSSGKGQSFIRSADQLSEAWRYAQQGGRAGAGRVIVEGVVNFDFEITLLTVSAVDGVHFCAPVGHRQEDGDYRESWQPQQMSDLALERAQAIARKVVLALGGHGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGAIRQYGPAASAVILPQLTSQNVSFGQLQSAVGAGLQLRLFGKPEIDGTRRLGVTLAVADSVEEAVARAKTAAAAVIVEG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RPPH_PECAS
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRYGQHSWQFPQGGINPGESPEQAMYRELFEEVGLRKKDVRVLASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLMCNESDINMQSSGTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFISPVILLQESVAARVATPPSPRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: DUT_BUCAI
Sequence: MSNIEIKILDSRMKNNFSLPSYATLGSSGLDLRACLDETVKLKAHKTILIPTGIAIYIANPNITALILPRSGLGHKKGIVLGNLVGLIDSDYQGQLMISLWNRSDQDFYVNPHDRVAQIIFVPIIRPCFLLVKNFNETSRSKKGFGHSGVSGVI
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PCYA_PARMW
Sequence: MQSPPSESSSTVAPLIPSLAETIRGAWIGLPELKPLDADSDFSSIEGQLEGDDLLIRNELLCCRGVRKIHLELARLGRGLQILHCVWFPDPRFDLPIFGADIVAGPAGVSAAIVDLSPVSGTLPSGIETALAGTPSPAFRQVRDLPGWGTIFSPHVCFIRPDGAEEEVLFRSRVEEVLTILRTAVLQTACEPATAASTIRRYEGQLSYCLQQKRNDKTRRVLEKAFDASWADRYIEELLFDDPLPPG
What is the function of this protein?
Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
What are the official names of this protein?
Phycocyanobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: PYRB_PYRAR
Sequence: MWRGRDVITMRDFGRGELEELFETAKYMEKYAKSRVDFLKGKIMAVAFFEPSTRTRLSFETAMRRLGGDVIGFWGAEGTSVEKGETLADTIRMLDAYSNIIVIRHKLEGAAKLAAEVAESPVINGGDGAFNHPTQAMLDLYTIWREFGHIDGLNIGLMGDLRYARTINSLLEALANFDVRTFLISPEYLRPRAETLDYVKSRGLKLSFHTNVEEVIHELDVLYVVRVQRERFLDPLEYERVKGSYRVTLEILKKAKKHLAILHPLPRVDEIDHRLDNTPHAKYFKQAALGVPLRMALIYLILSQP
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: FNDC5_MOUSE
Sequence: MPPGPCAWPPRAALRLWLGCVCFALVQADSPSAPVNVTVRHLKANSAVVSWDVLEDEVVIGFAISQQKKDVRMLRFIQEVNTTTRSCALWDLEEDTEYIVHVQAISIQGQSPASEPVLFKTPREAEKMASKNKDEVTMKEMGRNQQLRTGEVLIIVVVLFMWAGVIALFCRQYDIIKDNEPNNNKEKTKSASETSTPEHQGGGLLRSKI
What is the function of this protein?
Mediates beneficial effects of muscular exercise.  Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.
What are the official names of this protein?
Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, Peroxisomal protein, PeP.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Peroxisome membrane; Single-pass type I membrane protein. Secreted. Note=Imported in peroxisomes through the PEX5 receptor pathway. SUBCELLULAR LOCATION: [Irisin]: Secreted. Note=Detected in the blood of individuals subjected to endurance exercise.
Protein: LOLA3_DROME
Sequence: MDDDQQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDKHPIFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRTGGGVAPKPESSGHHRGGKLSGAYTLEQTKRARLATGGAMDTSGDVSGSREGSSSPSRRRRKVRRRSMENDAHDNSNSSVLQAAASNQSILQQTGAGLAVSALVTTQLSSGPAAGTSSQASSTQQQQPLTSTNVTKKTESAKLTSSTAAPASGASASAAVQQAHLHQQQAQTTSDAINTENVQAQSQGGAQGVQGDDEDIDEGSAVGGPNSATGPNPASASASAVHAGVVVKQLASVVDKSSSNHKHKIKDNSVSSVGSEMVIEPKAEYDDDAHDENVEDLTLDEEDMTMEELDQTAGTSQGGEGSSQTYATWQHDRSQDELGLMAQDAQQRDPQDLSITRIAGLTWNEWNARLAMPLVTLREGVQPLVFPTDLSVDKQQGAAGLTAKDVNVSGRKTPTDGGGCKSEPRAASTPARTHSSSNHSSNGNGSGKPTKTSSGGKLNHLTEEEATALMLKAVAEKQAAAAAGTELSFGEDQASSGNGNSSDYPATLSGAVTFADVGGPAGLCHINILNSISAMNNLISGSTAAGVGITTGSGQSPSNSGHNNSAGGGSSVLGGADNGAGHPCPVCGRVYKLKSSLRNHQKWECGKEPQFQCPFCVYRAKQKMHIGRHMERMHKEKFKLEDVKNFAGSSGLDGDSSGATATAASVVAAAAALVSGVELHPHFS
What is the function of this protein?
Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems.  Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.
What are the official names of this protein?
Longitudinals lacking protein, isoforms A/B/D/L.
What are the subcellular locations of this protein?
Nucleus.
Protein: LSPA_MYCA1
Sequence: MPEEPTGSTAPQDRPPRRLRLLLSVAATVLALDIVTKVLAVKLLPPGQPVPIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWAVGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVVLSIFGYDFDTVGRRKKADQSRD
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CJEA_CONPO
Sequence: MPSVRSVTCCCLLWMMFSVQLVTPGSPGTAQLSGHRTARFPRPRICNLACRAGIGHKYPFCHCRGKRDAVSSSMAV
What is the function of this protein?
Highly inhibits both nicotinic acetylcholine receptors (neuronal (IC(50)=8. 7 uM for alpha-3/beta-4) and muscular (IC(50)=0. 54 uM for alpha-1/beta-1/epsilon/delta) subtypes) and the voltage-gated potassium channel Kv1. 6/KCNA6 subtype (IC(50)=1. 59 uM).
What are the official names of this protein?
Alpha/kappa-conotoxin pl14a, Conotoxin PlXIVA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin J superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KATG_SHEB9
Sequence: MSENKCPMHHSAGGTTNRDWWPKQLRLDILHQHSSLSNPMGDDFNYAEAFKSLDLAAVKQDLLALMTDSQDWWPADFGHYGPLFIRMAWHSAGTYRTGDGRGGAGSGNQRFAPLNSWPDNVSLDKARRLIWPIKQKYGNKISWADLIVLTGNVALESMGFKTLGFAGGRVDIWEPEADIYWGAEDKWLDDKRYSGERDLEDPLAAVQMGLIYVNPEGPNGDPDPFAAAVDIRETFARMAMNDEETVALIAGGHTFGKTHGAGDAALVGPEPEAASIEQQGLGWKSSYKSGKGGDAISSGLEVTWTSTPTQWSNNFFENLFGYEWELTKSPAGAHQWIPKNGAGKGVIPDAHDASKRHVPAMLTTDLALIFDPDYEKISRRLFENPDEFAEIFAKAWYKLTHRDMGPCTRYLGPEVPAEEFLWQDPIPAVDHPLVDEQDVTDLKLKIIGSGLTISEVVATAWASASTYRGSDMRGGANGARIRLAPQKDWPVNQPEQLAKVLKVLESIQSEFNKSGKKISLADLIVLAGCVGIDQAARNAGVEVTIPFTPGRMDATQAQTDVESFAVLEPVADGFRNYHPTQFSVSAEELLVDRAQLLTLTAPEMTVLIGGLRVLDTNADQSKTGVFTARPEFLTNDFFVNLLDMGTTWKPTSKAEDRFEGVDRVSGQPKWTASRVDLIFGSNSQLRALAEVYASSDAQLRFIDDFIAAWTKVMNLDRFDLR
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: GLK_NEIG1
Sequence: MSSTPNKHADYPRLVADIGGTNARFALETAPCVIEKVAVLPCKEYDTVTDAVRAYLNQSGATGVRHAAFAIANPILGDWVQMTNHHWAFSIETTRQALGLDTLILLNDFTAQALAVTQTSSKDLMQVGGQKPVEFAPKAVIGPGTGLGVSGLVHSPAGWVALAGEGGHTSFPPFDDMEVLIWQYAKNKYRHVSAERFLSGAGLSLIYETLAVKQKAEPAKLMPSEITEKALNCESPLCRQALDIFCAMLGTVASNLALTLGARGGVYLCGGIIPRMLDYFKTSPFRSRFENKGRFEAYLAAIPVYVVLSEFPGIAGAAAALGNHLKNV
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM240_HUMAN
Sequence: MSMSANTMIFMILGASVVMAIACLMDMNALLDRFHNYILPHLRGEDRVCHCNCGRHHIHYVIPYDGDQSVVDASENYFVTDSVTKQEIDLMLGLLLGFCISWFLVWMDGVLHCAVRAWRAGRRYDGSWTWLPKLCSLRELGRRPHRPFEEAAGNMVHVKQKLYHNGHPSPRHL
What are the official names of this protein?
Transmembrane protein 240.
What is the protein family that this protein belongs to?
Belongs to the TMEM240 family.
What are the subcellular locations of this protein?
Synapse. Cell membrane; Multi-pass membrane protein.
Protein: PGLRA_ASPNG
Sequence: MPSAKPLFCLATLAGAALAAPAPSRVSDFTKRSTCTFTDAATASESKTSCSDIVLKDITVPAGETLNLKDLNDGTTVTFEGTTTWEYEEWDGPLLRISGKDITVTQSSDAVLDGNGAKWWDGEGTNGGKTKPKFFYAHDLDDSKISGLYIKNTPVQAISVESDNLVIEDVTIDNSDGDSEGGHNTDGFDISESTYITITGATVKNQDDCVAINSGENIYFSGGTCSGGHGLSIGSVGGRDDNTVKNVTFIDSTVSDSENGVRIKTVYDATGTVEDITYSNIQLSGISDYGIVIEQDYENGDPTGTPSNGVTISDVTLEDITGSVDSDAVEIYILCGDGSCSDWTMSGIDITGGETSSDCENVPSGASCDQ
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase A, Pectinase A, Polygalacturonase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGI_GEOMG
Sequence: MIKRIISIVFLLLTLPQLALAVRIKDIASFDGVRENQLIGYGLVVGLNGTGDSDQTNFPVQSLANVLERMGVTVNRNDITVKNVAAVMVTANLPPFAKQGTRIDTLVSSMGDAKSIAGGTLLMTPLKGADGRVYAVAQGGVLTNSFSYGGQAASAQKNHPTAGRVPNGGLVELELPNVLSDRGQLRLNLHQPDFTTATRIAQAVNERFKGGVAAATDPGAVMMNLPEAYKGRVVEFVADMERLEVRPDAMAKVVLNERTGTIVIGDNVRISTVAVSHGNLTLYIKETPKVSQPAPFSKTGETVVVPRTEIKVNEGGGGLAVVKEGASIGEVVRALNALGVTPRDLIGILQAIKAAGAMQAEVEVI
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: RL29_DESOH
Sequence: MKPDEIKALSADEAKQKLVELKAAYFNLRFRHETGQLDNTSMLEKTKKDIARVKTVLSAYNR
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: NUOA_SHISS
Sequence: MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARSKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.