PharMolix/UniProtQA huggingface dataset:
Protein: NADK_ALBFT
Sequence: MKSKFRHVALIGKYQTVASGASGASSRRVLEDIAHFLGAQGCEVVFEHDTAHNMGISGYPVLDVDAIGAKCDLGLVVGGDGTMLGIGRQLAKFGVPLIGINQGRLGFITDIPLDGYASALAPMLRGEFEEDHRSLMHARVMRDGRCVYDALAMNDVVVNRAATSGMVELRVEVDGHFVANQRADGLIIATPTGSTAYSLSAGGPLLHPSIPGWVLVPIAPHTLSNRPIVLANITEIAIEIISGRDASASFDTQSLASLLRGDRIVVTRSEHNVRFLHPRGWSYFDTLRQKLHWNEGVA
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_I83A4
Sequence: MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PHNH_RHIME
Sequence: MTAQSQIYSGAFADPVFEAQSVFRSLMDCFARPGIIGRLSTAAAPPAPLGEASGAVALTLCDHDTPVWLSPALSKSSAPKWIAFHTGAGVTDTKDEPRFAFFEKGAAVPGFDQFALGTQEYPDRSTTLVVEVEALEGGQPLIGRGPGIKNGIVIAPKGLPDVFLDLWAANRAIFPRGIDLVLTAREAVLCLPRTTKLERE
What is the function of this protein?
Together with PhnG, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate.
What are the official names of this protein?
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, RPnTP synthase subunit PhnH.
What is the protein family that this protein belongs to?
Belongs to the PhnH family.
Protein: SYH_STRS7
Sequence: MKLQKPKGTQDILPVAAAKWQYVEDVARETFKQYHYGEIRTPMFEHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQKPVKLYYIGSMFRYERPQVGRSREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKGVTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIAVANAPSILDYLDEDSQAHFDAVRSMLEALAIPYVIDTNMVRGLDYYNHTIFEFITEVNQSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIAVLGADANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADTFKAKVVITLGESEIKAGQAVLKHNQTRQEMTVSFDQIQTDFASIFAECVQ
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_CORDI
Sequence: MDNPTTPIAVVGPTASGKSALGVSLAHHLNGEVVNVDSMQLYKGMDIGTAKLTLEEREGIVHHLLDVWDISETASVARYQSQAIAVVEDIQRRGKTPILVGGSMLYVQSLVDDWQFPPTDPSVRAKWESKLNEVGVEALHALLAQKDPQAASIIELKDPRRTVRALEVIELTGKPFNASQPPKNAPPRWNTQIIGLGTNTEWLNPRIDLRTELMFEKGFVHEVENLVGKGLIADSTAGHAIGYAQVLQHFAGELSVDEMIEHTKIGTRRYVRRQRSWFKRDPRIHWIDASGDTFSMALSLLS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RNC_STRE4
Sequence: MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNERLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKLGRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKDYKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQDAAKNALAQLSEV
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQPZ2_RHIME
Sequence: MFKKLCAEFLGTCWLVLGGCGSAVLASAFPQVGIGLLGVSFAFGLTVLTMAYTVGGISGGHFNPAVSLGLAVAGRVPAASLVSYVIAQVAGAIIAAAVLYVIATGKADFQLGSFAANGYGEHSPGGYSLTAALVTEVVMTFFFLIIILGSTHRRVPAGFAPIAIGLALTLIHLVSIPVTNTSVNPARSTGQALFVGGWALSQLWLFWIAPLFGAAIAGIVWKSVGEEFRPVD
What is the function of this protein?
Channel that permits osmotically driven movement of water in both directions.  It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells.  It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
What are the official names of this protein?
Aquaporin Z 2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LYTH_STAAW
Sequence: MKKIEAWLSKKGLKNKRTLIVVIAFVLFIIFLFLLLNSNSEDSGNITITENAELRTGPNAAYPVIYKVEKGDHFKKIGKVGKWIEVEDTSSNEKGWIAGWHTNLDIVADNTKEKNPLQGKTIVLDPGHGGSDQGASSNTKYKSLEKDYTLKTAKELQRTLEKEGATVKMTRTDDTYVSLENRDIKGDAYLSIHNDALESSNANGMTVYWYHDNQRALADTLDATIQKKGLLSNRGSRQENYQVLRQTKVPAVLLELGYISNPTDETMIKDQLHRQILEQAIVDGLKIYFSA
What is the function of this protein?
Probably involved in cell-wall metabolism.
What are the official names of this protein?
Probable cell wall amidase LytH.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: EF1B_PYRAB
Sequence: MSDFNIVGVIKVMPSDPEVNLDELEEKLKAVIPEKYGLAKVEREPIAFGLVALKFYVLGKDEEGYSFDEVAEKFKEVENVESAEVETVSRI
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: ILVC_METTH
Sequence: MKIYYENDIDMEILADKKIAVIGYGSQGEAQARNMADSGLNVIVGLRRGGSSWKKAHDDGMNVMTIEDASREADIIHILIPDEIQETVFEQSIRPYLKEGNTISFSHGYNIHYGYIKAPEGVNVTMVAPKGPGAMVRRTYLEGFGIPGLVAVEVDATGDAMEQALAMAKACGLARAGVLETTFREETETDLFGEQAVLCGGVTELINTAFKTLVRAGYQPEIAYFETCHELKLIVDLIYERGFRGMWHNVSNTAEFGGLTRRGRIITEETEKEMDEILKEIQNGKFAKEWALENRAGAPMLKRMRKLESELEIEEVGSKLRKLCGLEK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PSPG_ECOLI
Sequence: MLELLFVIGFFVMLMVTGVSLLGIIAALVVATAIMFLGGMLALMIKLLPWLLLAIAVVWVIKAIKAPKVPKYQRYDRWRY
What is the function of this protein?
Effector of the phage shock response.
What are the official names of this protein?
Phage shock protein G.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes at both cell poles and along the length of the cell.
Protein: PAN_PYRAB
Sequence: MSGDEVQFHENYDDYITYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLRPGARVALDQRTMAIIELLPSSKDPTVLGFEVIERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLKNVDLRVIAEITEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAVDKVLGNERKLLQQITSHEIIYG
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX301_LYCSI
Sequence: MKFVLLFGVLLVTLFSYSSAEMLDDFDQADEDELLSLIEKEEARAKECTPRFYDCSHDRHSCCRSELFKDVCTCFYPEGGDNEVCTCQQPKHLKYMEKAAGKIKNLFG
What are the official names of this protein?
U3-lycotoxin-Ls1w, Toxin-like structure LSTX-B1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGB_CAUVC
Sequence: MTDVAEEAGWATAKTLAEALPYIQIYDRETVVIKYGGHAMGQEDVAKVFAADAVLLKLLGVHPVVVHGGGPQISRMLDKAGVKSTFVDGLRVTDEATMEVAEMVLSGAINKEIANWITLAGAEADVRGVGLSGKDARLITAEKVTRTKKDPDSNIEQAVDLGFVGEPTKVDPQLIEALLTSEHDYIPVVAPIGVSPDGDTFNINADTVAGALAGALKAKRMLMLTDIKGVLDGNGELIREMTIEQARALIDTGVATGGMIPKLENAIHAIESGVEAVVILDGRRPHAMLVELFSEYGAGTLIKR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHD_ECO8A
Sequence: MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCASVSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR
What are the official names of this protein?
D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: LEXA_CUPNH
Sequence: MATLTPRQQQIFDLIRNTIRRTGFPPTRAEIAAEFGFSSPNAAEEHLRALARKGVIELTPGASRGIRLKVAHSDSEMPDQFSLPMAGVMQLTLPLVGRVAAGSPILAAEHIDRQYQVDASVFDERPDYLLRVRGLSMRDAGILDGDLLAVRRASEAANGKIVVARLGDDVTVKRLQRRGGHIELIAENPDFTNIIVEPGEEFSLEGIAVGLIRSSGF
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CYSE_BACP2
Sequence: MFFKMLKEDIDTVFDQDPAARSYIEVVLTYSGLHAIWAHRIAHAFYKRKLYFLARIISQVSRFFTGVEIHPAATIGRRFFIDHGMGVVIGETCEIGDNVTVFQGVTLGGTGKEKGKRHPTILDDALIATGAKVLGSITVGKGAKIGAGSVVLKDVPDHSTVVGIPGRVVVQNGKKINRDLNHQDLPDPISDRFKELEREMEKLKGELASLSRKEEQS
What is the function of this protein?
Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS).
What are the official names of this protein?
Serine acetyltransferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRK7_PHYSG
Sequence: APPGFTPFRID
What is the function of this protein?
Produces in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle (By similarity).  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
[Ala1,Thr6,Asp11]-phyllokinin.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS2_BURO1
Sequence: MTQSTEDTLLRLAAVIDSRKGGDPDQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCLVMLSHFDLSPADVIAELERREGLSGIEEKALRKRREREENGG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
Protein: MYG_BUBBU
Sequence: MGLSDGEWQLVLNAWGKVETDVAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKKKGHHEAEVKHLAESHANKHKIPVKYLEFISDAIIHVLHDKHPSDFGADAQAAMSKALELFRNEMAAQYKVLGFHG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: G3P_HYPAT
Sequence: MSIKVGINGFGRIGRILLSNALEKPELSVVAVNDPFIEPTYAAYMLKYDSSHGLFKGDIEVDGQNLVVNGKPIRFYSERDPANIKWSETGAEYIVESTGVFTTIDKAKAHLNGGAKKVIISAPSADAPMFVMGVNHKDYDGTPTVLSNASCTTNGLAPLVKIVNDNFGIVEGLMTTVHSYTATQKTVDGPSGKDWRGGRGAAQNIIPSSTGAAKAVGKVIPAMNGKITGMSFRVPSANVSVIDLTVRLEKAASYEEITSAIKKAADGELKGIMAYTSDEVVSTDMLGNNNSSIFDIKAGISLNPNFVKLVSWYDNEWGYSRRVLDLLEHVAKVDASKK
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_ECOBW
Sequence: MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALACPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: DNAK_LEPBP
Sequence: MSKEKIIGIDLGTTNSCVAVMEGGDPVVIQNSEGARTTPSIVAFTAKGETIVGQFAKNQAITNAVNTIRSAKRFIGRRFNEAGDESKMVSYKVIRAGNDGVKFETVSGEFTPQEIAARVLQKMKKTAEDFLGHEVKKAVVTVPAYFNDEQRQATKDAGRIAGLEVERIINEPTAAALAYGFDKKKTNAKIAVYDLGGGTFDVSILELGDGVFEVKSTNGDTHLGGDDFDNVVMQWMIDEFKKQTGIDISGDKNTVQRLKEAAEKAKIELSGTSSTQINLPFITADASGPKHLDMTLTKAKFDEITRSLVERTRIPCINALKDAGLSASEIDEVILVGGSIRIPAVQALVKEIFGKEPNKSVNPDEVVAVGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVMTKLIERNTTIPTRKSQVFSTAADNQTTVSVHVLQGEREMASANRTLGRFDLVGIPSAPRGVPQIEVTFDIDANGIVHVSAKDLGTGKEQKIRIESSSGLSEEEIKKMVKDAEAHAEEDKKLREAADTKNELEAIVYQLEKTIGESADKLDESEKQRAQDEIKRGREAMESGDLERMKASRDSIQQVAMQIGQKIYSQAGPEQGAPGAEAGAGASQGASGTDANGEKVVDADYTVVDEDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YJGA_ECOSE
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: RSMH_WIGBR
Sequence: MHIPVMLNEVIKSIKIIPNGTYIDATFGCGGHSRCILSKLNEKGKLIVIDRDPKSIEFACSIKDRRLIPIHGNFSKILKYSIKYKIFGKVQGILFDLGLSFSQIKDSNRGFSFMHDGPLDMRMNNLHGISAKEWINNANIKDISFVIKEFGEEKFYKKISNVICKYRKIKNINTTKELVNLINKACGYFYKKKHPARRSFQAIRIYINNELQELKLALNDIIKIISPKGRIVFISFHSLEDRIIKKFIINNSRKKIYPYKLPILESKIKNDNIYKLKYFKKIQPSKKEILYNKKSRSAILRFAEKLKYD
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_CHRVO
Sequence: MALLQIAEPGLSAAPHQHRLAVGIDLGTTNSLVATVRSGSAAVLPDETGRSLLPSVVRYGDQGVLAVGYDAQKEQNRDPHNTIVSVKRFMGRGVSDIKDAGSLPYRFVDAPGMVQLVTRAGVKSPVEVSSDILRALKERAEASLGGELTGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNGSEGTYVVYDLGGGTLDVSILKLTRGVFEVLATSGDSALGGDDFDHRVFCWLLEQAGVTAPSAHDMRLLHTRAREAKEALTDHASTRVTAILSDGQSLDLELDQATLHAITKTLVDKTLTPVRKALRDAKIAPEDIQGVVMVGGATRMPHVQKAVADYFGRAPLTNLDPDKVVALGAAIQANVLAGNKQDDEWLLLDVLPLSLGIETMGGLTEKIIPRNSTIPVARAQDFTTFKDGQTAMSIHVLQGERELVSDCRSLAKFTLTGIPPMVAGAARIRITFQVDADGLLSVTAREQTSGVESSIEVKPSYGLSDDEISRMLSESLANVQEDIEARKLREAIVDAESLRDATLNALAQDGDLLDQAERAEVEAAVAAVASAIAEGVTRRVNEASAALNHATETFASRRMDRNIQRALKGHKITDL
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GYRA_MYCTU
Sequence: MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN
What is the function of this protein?
Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A, Type IIA topoisomerase subunit GyrA.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_SHEWM
Sequence: MRHYEIVFLVHPDQSEQVPGMIERYTGILTQAGGQIHRLEDWGRRQLAYPIIELHKAHYVLMNVEATAESVEELETAFRFNDAVLRNMVMRTKAAITEASPMAKAKDERDSRRASEGERRSAPAEATEEVTEAAEKTAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RSMJ_ACIBY
Sequence: MEKNCGSGQSKLKALRMHMYFEVDFQEQAQHYQAVLHSRGVTVDLQPIEKLNARFLRLNPDLALCVDENGLWLSANGMKMQPDWKAEIPRLKRASLKSEMIARACQLGEKPVLVDATAGLGHDSLLMAYLGAQIQLVERHPILFTLLEDSKAQAQHDPFLSQFMDRIQLIFADSASYLQQLDQEEKTVDVVYLDPMFPQRDQNQQAIKKQAQVKKQMQLLHLLLPEDGEMDLGDHLLELAKKVAKRVIVKRPRHAIFLANQEPAHQWQGDACRFDAYFQ
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRSA_VIBCH
Sequence: MSEASSKNLSETLFQNHKQAKETSSLTQYMPSSLELLDTRREQSSQAWYRNLRRLQWIWQGVDPVEQEEILARIASSKHSRTHDEWLDTVMGYRSGNWTYEWTRVGMLHQKQAAERQGEEAADQMFAAALYYSIAGYPHLRNDNLALQAQVLANNAYQEAAKLTGFVVKRLEFSYQNKKIAGYLHLRNTDSPKPVVLVSAGLDSLQTDMWRLFRDYLAKRDIAMLTIDMPSLGASSHWPLTEDSSCLHQAVLNQLADLPWVDHFRIGLIGFRFGGNAMARLAFLESDKVKACVSLGAPIHDIFTSPNKLAAMPKMYLDVLASRLGKNVVDVRSLSGQLMAWSLKVQGFMSGRRTKTPILALGLEGDPVSPYSDNQLVALFSQGGQAKKVKSKTISQGYEQSLDLAINWLEDELCK
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: RECF_FRAT1
Sequence: MYISNLRLQNFRNIPAKSFDFKNSINFIVGKNGSGKTSILESIYFLSHSRSFRSSQLNRIINHNADEFIIYTKAYNPDEITISLSRKKNSNNISKLNLEIQKNHTEITRNLPIQLINPESFNIINSGAQQRCKVLDWGAFYLDKTFLKIWQQTKFLVKQRNSALKQNYPYSYILSIDKKLCEFAEILDYKRQAYFTKLKPKIYEILSHFNPNLQLDIDYFRGWNLHKSLAQVLEESFNYDNKYKVTNHGPHKADIVLSVSHKPIQDIFSRGQQKLLICALKLAQGEIHNSENDNKCIYLIDDITSELDSIHTLTLFNYLKQLKSQVFITTTEKNKINEFIDTNSYILEI
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.