PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_ALKCK
Sequence: MTTILAIETSCDETAAAVIENGDTIRSNVVATQMESHARFGGVVPEIASRHHVEVVTAVVEEALEKAKVTYQDLTAVAVTEGPGLVGALLVGIHAAKAIAFAHGLPLIGVHHIAGHIYANQLVAKLQFPLLALVVSGGHTELIYMEKDGQFQVIGQTRDDAVGEAYDKVARALALPYPGGPNVEQLADTAEATLDLPRSWLEKDSYDFSFSGLKSAVLNRLNNDKQRGIVTDRAALAKGFQESVVDVLVAKTVRAQAQFNVKQVVLAGGVAANKGLRKALTEAFANKDVTLLVPPLSLCTDNAAMIGACAHSMWLRGIAGNMAMNARPGLPLSSF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA_SOYBN
Sequence: MATATNAAAAPPRQLSQKEADIQMMLAADVHLGTKNCDFQMERYIFKRRNDGIYIINLGKTWEKLQLAARVIVAIENPQDIIVQSARPYGQRAVLKFAQYTGAHAIAGRHTPGTFTNQLQTSFSEPRLLILTDPRTDHQPIKEAALGNIPTIAFCDTDSPMRYVDIGIPANNKGKHSIGCLFWLLARMVLQMRGTIRPGLKWDVMVDLFFYREPEEAKQQEEEEAPAVDYAITDFNAGAIAADGQWPGTIDQSWSDAVPQPIPAVPGVNWGAPAEAPAAAGGDWGEAVPPPQQIPVPPSGIDTVQPSGWD
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA, p40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_CORGL
Sequence: MTTIDLNSDLGESYGSWVMGNDVAVLDLVSSANIACGFHAGDATVLFKTVRAAHARHVRIGAHIGYNDIAGFGRRNLDIAHDDLVAETIYQIGAIQAAAKASGAVVEYVKPHGALYNTIAVDEAQAAAVIEGIKLVNPELSLMALAGSQIVEQARAVGLQVEQETFADRAYTADGQLVSRKLPGAVLHDPETAARQALAFATGQPITAITGESVLVDANSICVHGDNPQALALVEKIVTTLAAHEVQVSHAR
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: GRCA_HAEDU
Sequence: MIKGIQITESSNNNLVNSFWLLDEEKNEARCIAAKGDVYQEDQVIAINELGQIAYREIPVNIAPTIKVEGGQHLNVNVLRRETLEDAIKNPEKYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: MEC10_CAEBR
Sequence: MNRGPPNPRMFKFQPNPKVKNRFQDEADLRSLRSFKTDFSNYLASDTNFLNVAEIMTSYAYGESNNANEKEIQCDLLTENGGIEIDPTRLSYRERIRWHLQQFCYKTSSHGIPMLGQAPNSLYRAVWVFLLLICAIQFINQAVAVIQKYQKMDKITDIQLKFDTAPFPAITLCNLNPYKDSVIRSHDSISKILGVFKSVMKKAGDSSAEASDDGVEYDMDGITIQAKRRKRGAGEKGTFEPANSACECDEEDGSNECEEKSTEKPSSDNDMCICAFDRQTNDAWPCHRREQWTNTTCQACDEHYLCSKKAKKGTKRSEIKKEPCICESKGLFCIKHEHAALVLNLWEYFGDTEEFSDISTEEREALGFGNMTDEVAIVTKAKENIIFAMSASEEQRILMSQAKHNLIHKCSFNGKPCDIDKDFELVADPTFGNCFVFNHDREIFKSSVRAGPQYGLRVMLFVNASDYLPTSEAVGIRLTIHDKDDFPFPDTFGYSAPTGYISSFGMRMKKMSRLPAPYGDCVEDGTTSNYIYKGYAYSTEGCYRTCFQELIIDRCGCSDPRFPSIGGVQPCQVFNKNHRECLEKHTHQIGEIHGSFKCRCQQPCNQTIYTTSYSEAIWPSQALNISLGHCEKEAEECNEEYKENAAMLEVFYEALNFEVLAESEAYGIVKMMADFGGHLGLWSGVSVMTCCEFVCLVLELLYMAVTHHITQERIRRRENAANEF
What is the function of this protein?
Amiloride-sensitive sodium channel subunit required for mechanosensory transduction (touch sensitivity).  Negatively regulates the turning step of male mating behavior.
What are the official names of this protein?
Degenerin mec-10, Mechanosensory abnormality protein 10.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIBD_ACTPL
Sequence: MCFPLPSNSFKTMTDLDYMRRAIALAKQGLGWTNPNPLVGCVIVKNGEIVAEGYHEKIGGWHAERNAVLHCKEDLSGATAYVTLEPCCHHGRTPPCSDLLIERGIKKVFIGSSDPNPLVAGRGANQLRQAGVEVVEGLLKEECDALNPIFFHYIQTKRPYVLMKYAMTADGKIATGSGESKWITGESARARVQQTRHQYSAIMVGVDTVLADNPMLNSRMPNAKQPVRIVCDSQLRTPLDCQLVQTAKEYRTVIATVSDDLQKIEQFRPLGVDVLVCKARNKRVDLQDLLQKLGEMQIDSLLLEGGSSLNFSALESGIVNRVHCYIAPKLVGGKQAKTPIGGEGIQQIDQAVKLKLKSTELIGEDILLDYVVISPL
What is the function of this protein?
Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HTP reductase family.
Protein: GATC_LACDB
Sequence: MEKVTNDTIKHVAALAQLEFSEEELAKFTPQMGKILEMAEELQAVDTTGVEETVQVVDRDTVFREDVPEKWQTREEMMKNVPDKSNGFVKVPVIIDKDDNQ
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CC140_HUMAN
Sequence: MGDECSNPDLLAEPGSSPPWDHGNQRQEAANESNTRVPRVLKAHLGPETAQPTKRSKRNRWRRQSCQGPSPARSGQFLGSADLGLQRGVLKSAARTCLSEISNSTRASPESAQSTDPGRAARPRTRTLPTPHSFKIGEEAEEMKKKKERKRRKERKKERNFKK
What are the official names of this protein?
Coiled-coil domain-containing protein 140.
Protein: ATG15_ASPNC
Sequence: MKGLRGHNKKSFWGNTRLSDLLWPVTLLPGLISAYQPVYLGSRQSSPFLPPQIPLGDSPPLSDTHEFTLRHIFHRGTYQDPDLHRRLDITPDTRLRAVSDAGIESDVVTPNTPLVASSQPLIIERLADRRLSVIEEHLVTARSSGSAVALSPSDWVMDTLPGPNVTEKKTVVALAMMTANDYIEVPGTGDWQDIHGRFNHSGSFGWQGDGLRGHVYADKTNSTVVISLKGTSPALFDGEGTTTNDKINDNLFFSCCCGQGGSYLWRQVCDCQTTLYNANLTCIVEAMLDENRYYRASLDLYSNITEMYPNANVWLTGHSLGGAVSSLLGLTFGVPVVTFEAVPEALPAARLGLPSPPGHDSRYPQSRRNTGSYHFGHTADPVYMGTCNGVSSVCTWGGYAMESACHTGQMCVYDTVEDKGWRVGLSKHRINYVIANVLAGYDDVPPCAPEEECYDCELWKFFRSNGSEITTTTSATSTSTSTTTSRTSTCKTPGWWGCLDQTTTTETTSTSTSTSTCKTPGWFGCKDPTTTSDITSVPTITTTEPPMTSTTTCKTPGWFGCKDETTTQVIAPAATLTITEPPVTSTTTGKHLGRF
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by atg15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase atg15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: NIKR_DICT6
Sequence: MTKIVRFGVSVEEDLLENFDKIIENKGYNSRSEAIRDLMRDYIIKEKWNIKSEKVAGSISLIYEHDVYGLSEKLTDIQHHYHDVIISTLHVHLDEKNCMEVILVRGKVEKIKKLYNEISSLKWVRHTNISITDII
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: MRAY_RUTMC
Sequence: MFLELINFLAQFDAGFNVLNYLTVRAILAMLSALFFSLMLGRVFINQLQQYQIGQIIRTDGPKSHLIKAGTPTMGGILILFTFMISVLIWGDWSNIYLWIVIVTSIIFGTIGFTDDYIKIKHKSSNGLSFSIKFLTQSLGAIVISTWIVLISQDSIQTQLLIPFFKDTMLPLGIIGFLILSYFVIVGSSNAVNLTDGLDGLAIMPVILISGALAIFAYLSGHYNFSSYLNIPFMPGTGELFVICAALIGAGLGFLWFNTYPAEIFMGDVGSLFLGAILAVITILIRQEILLFIMGSVFVAETLSVIIQVSYYKRYKKRIFLMAPLHHHFEKKGMSEPKIIVRFWMVTLILVLVSLASIKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECF_SALAI
Sequence: MYVRRLELVDFRSYERVGVDLEPGANVLVGHNGVGKTNLIEALGYVATLDSHRVATDAPLVRMGAGAAVIRCAVVHEGRELLIELEIVPGRANRARLGRSPARRARDVLGALRLVLFAPEDLELVRGDPAERRRYLDDLLVLRQPRYAGVRADYERVVRQRNALLRTAYLARKTGGTRGGDLSTLAVWDDHLARHGAELLAGRLDLVAALAPHVTRAYDAVAAGTGAAGIAYRPSVELPTPTTDRADLTAALSAALAAGRSAEIERGTTLVGPHRDDLTLTLGPLPAKGYASHGESWSLALALRLAGYDLLRVDGIEPVLVLDDVFAELDTGRRDRLAQLVGDASQLLVTCAVEEDVPARLRGARFVVRGGEVHRA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_SHEB5
Sequence: MAVQQNKKSRSKRGMRRSHDALSTAQLSVDATSGEIHMRHNVTADGFYRGKKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: Y3805_MYCTA
Sequence: MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSIPPNLFVSAQRATS
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MRA_3805.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: BOXC_AROEV
Sequence: MQAVANKPVAELVDYRTEPSKYRHWSLATDGEIATLTLNIDEDGGIRPGYKLKLNSYDLGVDIELHDALQRVRFEHPEVRTVVVTSGKPKIFCSGANIYMLGLSTHAWKVNFCKFTNETRNGIEDSSQYSGLKFLAACNGTTAGGGYELALACDEIVLVDDRNSSVSLPEVPLLGVLPGTGGLTRVTDKRRVRRDHADIFCTISEGVRGQRAKDWRLVDDVVKQQQFAEHIQARAKALAQTSDRPAGAKGVKLTTLERTVDEKGYHYEFVDATIDADGRTVTLTVRAPAAVTAKTAAEIEAQGIKWWPLQMARELDDAILNLRTNHLDVGLWQLRTEGDAQVVLDIDATIDANRDNWFVRETIGMLRRTLARIDVSSRSLYALIEPGSCFAGTLLEIALAADRSYMLDAAEAKNVVGLSAMNFGTFPMVNGLSRIDARFYQEEAPVAAVKAKQGSLLSPAEAMELGLVTAIPDDLDWAEEVRIAIEERAALSPDALTGLEANLRFGPVETMNTRIFGRLSAWQNWIFNRPNAVGENGALKLFGSGKKAQFDWNRV
What is the function of this protein?
Catalyzes the ring opening of 2,3-epoxy-2,3-dihydroxybenzoyl-CoA to form 3,4-didehydroadipyl-CoA semialdehyde.
What are the official names of this protein?
Benzoyl-CoA-dihydrodiol lyase.
What is the protein family that this protein belongs to?
Belongs to the benzoyl-CoA oxygenase component C family.
Protein: GHRB_ECO5E
Sequence: MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_HELPS
Sequence: MVFYKYSGSGNDFLIVQSFKKKDFSNLAKQVCHRHEGFGADGLVVVLPSKDYDYEWDFYNSDGSKAGMCGNASRCVGLFAYQHAIASKNHVFLAGKREISICIEEPNIIESNLGNYKILDTIPALRCEKFFTNDSVLENIPTFYLIDTGVPHLVGFVKNKEWLNSLNTLELRALRHAFNANINIAFIENKETIFLQTYERGVEDFTLACGTGMAAVFIAARIFYNTPEKAALIPKSSESLELSLKNDEIFYKGAVRYIGMSVLGMSVFENGCF
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDPK1_ARATH
Sequence: MGNTCVGPSRNGFLQSVSAAMWRPRDGDDSASMSNGDIASEAVSGELRSRLSDEVQNKPPEQVTMPKPGTDVETKDREIRTESKPETLEEISLESKPETKQETKSETKPESKPDPPAKPKKPKHMKRVSSAGLRTESVLQRKTENFKEFYSLGRKLGQGQFGTTFLCVEKTTGKEFACKSIAKRKLLTDEDVEDVRREIQIMHHLAGHPNVISIKGAYEDVVAVHLVMECCAGGELFDRIIQRGHYTERKAAELTRTIVGVVEACHSLGVMHRDLKPENFLFVSKHEDSLLKTIDFGLSMFFKPDDVFTDVVGSPYYVAPEVLRKRYGPEADVWSAGVIVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAKDLVRKMLVRDPKKRLTAHQVLCHPWVQVDGVAPDKPLDSAVLSRMKQFSAMNKFKKMALRVIAESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTIDYKEFIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQACEEFGVEDVRIEELMRDVDQDNDGRIDYNEFVAMMQKGSITGGPVKMGLEKSFSIALKL
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger.  Phosphorylates the Ca(2+)-ATPase ACA2 resulting in the inhibition of its calcium activation.
What are the official names of this protein?
Calcium-dependent protein kinase 1, AtCDPK 1, CDPK 1, Calcium-dependent protein kinase isoform AK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Peroxisome membrane; Lipid-anchor.
Protein: HEM1_YEAST
Sequence: MQRSIFARFGNSSAAVSTLNRLSTTAAPHAKNGYATATGAGAAAATATASSTHAAAAAAAAANHSTQESGFDYEGLIDSELQKKRLDKSYRYFNNINRLAKEFPLAHRQREADKVTVWCSNDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLLQSYPKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVGGYVAASRKLIDWFRSFAPGFIFTTTLPPSVMAGATAAIRYQRCHIDLRTSQQKHTMYVKKAFHELGIPVIPNPSHIVPVLIGNADLAKQASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAVDDVFNELQLPRVRDWESQGGLLGVGESGFVEESNLWTSSQLSLTNDDLNPNVRDPIVKQLEVSSGIKQ
What is the function of this protein?
Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
What are the official names of this protein?
5-aminolevulinate synthase, mitochondrial, 5-aminolevulinic acid synthase, Delta-ALA synthase, Delta-aminolevulinate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MINE_SHESR
Sequence: MSLLDYFKSKKKPSTAVMAKERLQIIVAHQRGQRDTPDYFPQMKQEIIAVIRKYVHISDDQVSVQLDQNDDNLSVLELNVTLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: LEUD_ESCF3
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKVGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEAKQPAFMN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PLCD3_ARATH
Sequence: MSESFKVCFCCSRSFKEKTRQPPVSIKRLFEAYSRNGKMSFDELLRFVSEVQGERHAGLDYVQDIFHSVKHHNVFHHHGLVHLNAFYRYLFSDTNSPLPMSGQVHHDMKAPLSHYFVYTGHNSYLTGNQVNSRSSVEPIVQALRKGVKVIELDLWPNPSGNAAEVRHGRTLTSHEDLQKCLTAIKDNAFHVSDYPVIITLEDHLPPKLQAQVAKMLTKTYRGMLFRRVSESFKHFPSPEELKGKILISTKPPKEYLESKTVHTTRTPTVKETSWNRVANKILEEYKDMESEAVGYRDLIAIHAANCKDPSKDCLSDDPEKPIRVSMDEQWLDTMVRTRGTDLVRFTQRNLVRIYPKGTRVDSSNYDPHVGWTHGAQMVAFNMQGHGKQLWIMQGMFRGNGGCGYVKKPRILLDEHTLFDPCKRFPIKTTLKVKIYTGEGWDLDFHHTHFDQYSPPDFFVKIGIAGVPRDTVSYRTETAVDQWFPIWGNDEFLFQLSVPELALLWFKVQDYDNDTQNDFAGQTCLPLPELKSGVRAVRLHDRTGKAYKNTRLLVSFALDPPYTFR
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
What are the official names of this protein?
Phosphoinositide phospholipase C 3, Phosphoinositide phospholipase PLC3, AtPLC1F, AtPLC3, PI-PLC3.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: 1A1D_PSEFL
Sequence: MNLNRFKRYPLTFGPSPITPLKRLSEHLGGKVELYAKREDCNSGLAFGGNKTRKLEYLIPEALEQGCDTLVSIGGIQSNQTRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIEMSRIMGADVRLDAAGFDIGIRPSWEKAMNDVVERGGKPFPIPAGCSEHPYGGLGFVGFAEEVREQEKQLGFKFDYIVVCSVTGSTQAGMVVGFAADGRSKNVIGIDASAKPEKTKAQILRIARHTAELVELGREITEDDVVLDTPFAYPEYGLPNEGTLEAIRLCGSLEGVLTDPVYEGKSMHGMIEMVRRGEFPEGSKVLYAHLGGAPALNAYSFLFRNG
What is the function of this protein?
Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.  Allows growth on ACC as a nitrogen source.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate deaminase, ACC deaminase, ACCD.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: PHNW1_PARXL
Sequence: MQPRRGEPYLLTPGPLTTAFSTKEAMLRDWGSWDGDFRAMTALLRSSLLEIAGDTAGEYDCVPLQGSGSYCVEAMLGSLIPRDAHALVLANGAYGKRIVTTLGYLGRACTVLDKGDYLPPRGAEIERMLDDDPRITHVVAVHCETSSGILNPIEEIAAATAKKGRKLLIDSMSAFGAVPLDVREIACEAFVSSANKCIEGVPGFGFVIARKSALREAKGRSHSLALDVYDQWDVMNRTGQWRFTPPTHAVAAFIEALRLFRLEGGQVGRLARYANNRDVLVAGMRELGFEPLLNARWRSPVIVTFFAPAHPSFRFETFYELMKQQGFIIYPGKLTVVDSFRIGCIGQVDEHVMRRVVEACANSLRTMGVGHAAPPAAALEERRTLAEAA
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase 1, 2-aminoethylphosphonate aminotransferase 1, AEP transaminase 1, AEPT 1.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: RPOA_CLOB8
Sequence: MLEIEKPIIECIEANEDGTYGKYVVEPLERGYGITLGNALRRILLSSLPGVATTSVKIDGVLHEFSTVQGVKEDVTELILNIKSLALRMNGEGPKVIYIDAKGPGEVTGADIKTDGDVEVVNKNLHIATLDNDGRLYMELTVNKGRGYVTQNKNKSDELPISAIAVDSIYTPVKRVNFTVDNTRVGQITDYDKLTLEIWTNGTIKIDEAISLSAKILIEHFKLFMSLTDNTNDVEIMIEKEDDKKEKVLEMTVEELDLSVRSYNCLKRAGINTVQELATKSMDDMMKVRNLGKKSLEEVERKLKELGLALKLTEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: CAPSD_HBVCP
Sequence: MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPNHTALRQAILCWGELMTLASWVGNNLEDPASREQVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSPASQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: ATPE_CAMJ8
Sequence: MNDLINFEIVTPLGVIYQGEVKSVTLPGSEGEFGVLKGHATLVSSLKSGVIDIEKADLNHELIAIDAGHAKVDEDKICVLAKGAVWVCGSDESEIEKNLAQAKDLIKSMSSDNAALAATFSKLDNARMH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RUTD_CAUSK
Sequence: MQSGTVDGLYHEVHGGPASDRQTVILSAGLGGSGTFWAPQMQALMSRFRVVLYDHRGTGRSARTLTDPHTVAAMGDDIVKLMDALGLERAHVVGHAAGGNAGLALALNHPDRLDKLVVVNGWSRPDPHIKRCFDTRLALLNDTGIAAYVHAQPLFLYPADWLSANNARLEAEEVHHINGFPSPDVMRTRIQALLEFDIDEDLETIRCPVLVSASADDMLVPLSCSRRLAERLPNATLDIAPWGGHGFTVTAPEAFNAAVLNFLSGEAA
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.