PharMolix/UniProtQA huggingface dataset:
Protein: RCL1_DICDI
Sequence: MLKFQGSTHFRQRIICSTLSGKAIRITNIRDEDEKPGLRDYEASFLRLVDKITNGSKIEINSTGTQITYIPGIIIGGKGITHECGTVRGIGYFVEALICLGPFAKAPLDITLNGITNNDIDLTIDTIRTTTLPIIRKFGIEEGLIIKIIKRGAPPNGGGSVNFKCPIVPHLKAIQLIDEGKIRRIRGIAYATRISPQFSNRVLDKAKGLLLEYTPDVYISSDHYKGNESGLSPGYGLTLVAETTTGCCLSAECMSNTGIATTEQQLQKQKSTSETPEDLGERTAFALLEEIFNGGCIDSHNQSLALLFMVLCPEDISKVRLGKITPYTIEFIRQLRDFFGVTFKIEPDQNSKTVLFTCLGIGYKNMARSTF
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  Does not have cyclase activity (By similarity).
What are the official names of this protein?
Probable RNA 3'-terminal phosphate cyclase-like protein.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YEER_ECOLI
Sequence: MLQIVGALILLIAGFAILRLLFRALISTASALAGLILLCLFGPALLAGYITERITRLFHIRWLAGVFLTIAGMIISFMWGLDGKHIALEAHTFDSVKFILTTALAGGLLAVPLQIKNIQQNGITPEDISKEINGYYCCFYTAFFLMACSACAPLIALQYDISPSLMWWGGLLYWLAALVTLLWAASQIQALKKLTCAISQTLEEQPVLNSKSWLTSLQNDYSLPDSLTERIWLTLISQRISRGELREFELADGNWLLNNAWYERNMAGFNEQLKENLSFTPDELKTLFRNRLNLSPEANDDFLDRCLDGGDWYPFSEGRRFVSFHHVDELRICASCGLTEVHHAPENHKPDPEWYCSSLCRETETLCQEIYERPYNSFISDATANGLILMKLPETWSTNEKMFASGGQGHGFAAERGNHIVDRVRLKNARILGDNNARNGADRLVSGTEIQTKYCSTAARSVGAAFDGQNGQYRYMGNNGPMQLEVPRDQYAGAVETMRNKIREGKVEER
What are the official names of this protein?
Inner membrane protein YeeR.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_SHEFN
Sequence: MDKKTSRLRRALRARKKIQELGVNRLVVHRTPRHIYAQVINPEAQVLAVASTVEKAVKELLKSTGNVDAAKAVGKIVAERAIEKGVATVAFDRSGFKYHGRVAALADAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: FPG_STRP1
Sequence: MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALTLPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGSTVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRL
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: GRCA_YERPS
Sequence: MITGIQITKANNEALLNSFWLLDDEKAELRCVCAKSGYAEDQIVPTSELGEIEYREVPLEVQPTVRVEGGQHLNVNVLSRDTLEDAVKNPEKYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: UBIG_BURO0
Sequence: MTNADPHELQKFSDLAHRWWDPNAEFKPLHDLNPVRLGWIDAHAHLAGKRALDIGCGGGILSESMAGLGAQVKGIDLSTEALGVADLHSLESGISVEYEAIAAEAIAAREPGTYDVVTCMEMLEHVPSPGDIVAACATLVKPGGWVFFSTLNRNLKSYLFAVIGAEYIAQMLPKGTHDYARFIRPSELASFVRATDLHIVEIKGITYHPIGKRFALSNDTDINYLVACRRGA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: GLYC_BRSV2
Sequence: MSNHTHHPKFKTLKRAWKASKYFIVGLSCLYKFNLKSLVQTALTSLAMITLTSLVITAIIYISVGNAKAKPTSKPTTQQTQQPQNHTPLLPTEHNHKSTHTSTQSTTLSQPPNIDTTSGTTYGHPINRTQNRKIKSQSTPLATRKLPINPLESNPPENHQDHNNSQTLPHVPCSTCEGNPACSPLCQIGLERAPSRAPTITLKKAPKPKTTKKPTKTTIYHRTSPEAKLQTKKNTATPQQGILSSPEHQTNQSTTQISQHTSI
What is the function of this protein?
Helps the virus escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fc-gamma receptors.
What are the official names of this protein?
Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG.
What is the protein family that this protein belongs to?
Belongs to the pneumoviruses glycoprotein G family.
What are the subcellular locations of this protein?
[Isoform Membrane-bound glycoprotein G]: Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform Secreted glycoprotein G]: Secreted. Note=The protein is shed from infected cells before the appearance of progeny virus. The initiation at the downstream methionine removes a portion of the transmembrane domain. The remaining hydrophobic portion of the sG protein is essential for translocating it into the lumen of the ER during translation and would likely maintain its membrane association until a proteolytic event releases the mature sG protein into the medium.
Protein: PANE_VIBCH
Sequence: MNIVVLGPGAVGSLWALHLHSAGHQVALWSRQAQPTITLQLDEEAPISFRNQNLDTLIHADLLLITVKAWQVEAALQPLLPHLNRETILLFMHNGMGAVEAISESLTHFPVLFATTTHGALKATLNQVSHTGFGQTQVGPFNALGARCDFIADVFNHALAPVTWNPEIQQALWRKLAVNCAINPLTAIHQCANGALVAPEFTPIITAILDEVTAVMQAEAISGEAEALRDGVYQVIQATAANLSSMHQDVFHRRPTEIDFITGYVVRKGEQHGIATPVNSALYQQIKTLEQSWSKA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VW5B1_HUMAN
Sequence: MPGLLNWITGAALPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVIGFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSIAPHSCTPGKVTLDEDLERILFVANLGTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRHCFGAWAPGSWNKLCLATLLNTEVSNPMEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPSARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKGDMTLGEFDQHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGAVNNTGKVLELVRNHAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLKKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDASLHISNPRSDKRRRYSMLHSQESGSSVFYHSQDDGPGLEGGDCAKNSGAPFILGQAKNARLASGDSTTKHDLNLSQRRRAYSTNQITNHKPLPRATMASDPMPAAKRYPLRKARLQDLTNQTSLDVQRWQIDLQPLLNSGQDLNQGPKLRGPGARRPSLLPQGCQPFLPWGQETQAWSPVRERTSDSRSPGDLEPSHHPSAFETETSSDWDPPAESQERASPSRPATPAPVLGKALVKGLHDSQRLQWEVSFELGTPGPERGGAQDADLWSETFHHLAARAIIRDFEQLAEREGEIEQGSNRRYQVSALHTSKACNIISKYTAFVPVDVSKSRYLPTVVEYPNSAALRMLGSRALAQQWRGTSSGFGRPQTMLGEDSAPGNGKFQALNMEASPTALFSEARSPGREKHGASEGPQRSLATNTLSSMKASENLFGSWLNLNKSRLLTRAAKGFLSKPLIKAVESTSGNQSFDYIPLVSLQLASGAFLLNEAFCEATHIPMEKLKWTSPFTCHRVSLTTRPSESKTPSPQLCTSSPPRHPSCDSFSLEPLAKGKLGLEPRAVVEHTGKLWATVVGLAWLEHSSASYFTEWELVAAKANSWLEQQEVPEGRTQGTLKAAARQLFVLLRHWDENLEFNMLCYNPNYV
What are the official names of this protein?
von Willebrand factor A domain-containing protein 5B1.
What are the subcellular locations of this protein?
Secreted.
Protein: YPFN_SALHS
Sequence: MDWLAKYWWILVLVFLVGVLLNVIKDLKRIDHKKFLANKPELPPHRDFNDKWDDEEDWPKKDQPKK
What are the official names of this protein?
UPF0370 protein YpfN.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS10_ACIAC
Sequence: MSKQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAIVKGPVPLPTRMKRFDILRSPHVNKTSRDQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: OSPA_BORBU
Sequence: MKKYLLGIGLILALIACKQNVSSLDEKNSVSVDLPGEMKVLVSKEKNKDGKYDLIATVDKLELKGTSDKNNGSGVLEGVKADKSKVKLTISDDLGQTTLEVFKEDGKTLVSKKVTSKDKSSTEEKFNEKGEVSEKIITRADGTRLEYTGIKSDGSGKAKEVLKGYVLEGTLTAEKTTLVVKEGTVTLSKNISKSGEVSVELNDTDSSAATKKTAAWNSGTSTLTITVNSKKTKDLVFTKENTITVQQYDSNGTKLEGSAVEITKLDEIKNALK
What is the function of this protein?
Induces host (human and mouse) cytokine release by monocyte cell lines via TLR2 and CD14; nonlipidated protein does not stimulate host cells (PubMed:10426995).
What are the official names of this protein?
Outer surface protein A.
What is the protein family that this protein belongs to?
Belongs to the OspA lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: YGAC_ECOL6
Sequence: MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARMGRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVALERYLNGLFGEAS
What are the official names of this protein?
Uncharacterized protein YgaC.
Protein: PXPA_ECO57
Sequence: MKIDLNADLGEGCTSDAELLTLVSSANIACGFHAGDAQTMQACVREAIKNGVAIGAHPSFPDRKNFGRSAMQLPPETVYAQTLYQIGALATITRAQGGVMRHVKPHGMLYNQAAKEAQLADAIARAVYACDPALVLVGLAGSELIRAGKQYGLTTREEVFADRGYQADGSLVPRSQSGALIEDEEQALAQTLEMVQHGRVKSITGEWATVTAQTVCLHGDGEHALAFARRLRSAFAEKGIVVAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: PSAA_TORCL
Sequence: LKIVVERDPIKTSFEKWAKPGHFSKTLAKGPNTTTWIWNLHADAHDFDSHTNDLEEISRKVFSAHFGQLAIIFIWLSGMYFHGARFSNYEAWLGDPTHIKPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTATGALIFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLGWAGHQVHVSLPINQLLDAGVDPKEIPLPHEFISNRDLLAQLYPSFAEGLTPFFTLNWSEYSDFLTFRGGLNPVTGGLWLTDTAHHHLAIAILFLIAGHMYRTNWGIGHNLKEILEAHKGPFTGEGHRGLYEILTTSWHAQLALNLAMLGSLTIVVAHHMYSMPPYPYLAIDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTQYNNLLDRVLRHRDAIVSHLNWACIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPIFAQWIQNTHASSPSLTAPDATASTSLTWGGGDLVAVGAKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKVNLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIVQGRAVGVA
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: THI4_SULTO
Sequence: MDSNSIKVKQVDEVKISKYILKYTFQDWEDIVESDVVIVGAGPSGMTAAYYLAKAGLKTVVFERRLSFGGGIGGGAMLFHKIVIESPADEILKEMKIKLNKVEEGVYIVDSAEFMAKLAASAIDAGAKIIHGVTVDDVIFRENPLKVVGVAVEWTATQMAGLHVDPLFISAKAVVDATGHDAEVISVAARKIPELNIVIPGEKSAYSETAEELTVENTGMVAPGLYAAGMAVTEVKGLPRMGPIFGAMVLSGKRVAEIIIKDLRYS
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: RL16_CHLTR
Sequence: MLMPKRTKFRKQQKGQFAGLSKGATFVDFGEFGMQTLERGWITSRQIEACRVAINRYLKRKGKVWIRVFPDKSVTKKPAETRMGKGKGAPDHWVVVVRPGRILFEVANVSKEDAQDALRRAAAKLGIRTRFVKRVERV
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SL8_ECHCS
Sequence: MGRFIFVSFSLLVVFFSLSGTEAGVCCPLGWSGYDQNCYKAFEELMNWADAEKFCTQQHKGSHLVSLHNIAEADFVVKKIVSVLKDGVIWMGLNDVWNECNWGWTDGAQLDYKAWNVESNCFIFKTADKPLVTYGLQWDTQFRLQEPG
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 8, C-type lectin 8, CTL-8.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: CGLA_PSEAS
Sequence: MKIKILSAMIASSLLIGCVIPTVKASQSAIKSIETNRTITKVRTGMLSGGSSIITTSYEGTVAAYKFNGEKLWENELSGFMNHDIWVQDINGDGLVEIFAANADGNVYCINSDGSLKWTFGLNEVPMNSVTVISDADEKYVVAGGYDKNLYYISANGELLKTIESSAYSEEGVFGDGVKPEARTHTVNFVRPVKSSDGTEKLVVLGTNNSLQSSGRFYIFEPFADLPSEKSRISIKKGIGDLRTVDFDNDGNDELTLGNSAQIGDAAISVMNLDDLSQKKSQINDIARRIDRFGYRVAQTEVVMNEGTPTYLTLFGSRILLTPESFDVNDSEILANKYSYYDIWKDKSSNKLVLASAQSGGSQVHIIDTSNPSWKSAYEELEPQGKLAAIQENTREVERQLSNFQKPTRERAPLPVYFISESRNEIPATIERSESLYDSPVFLNYSTLPNVENWDRSEVLADNPKYRDKRDRRKNYTLSSEEMFNKLSAGYESSDGISQWAGHGNDPYMISLATMKRIISSGDGKKTVNIYPEIEGHGDAFNKVLNDHFYPLAEFSSENNANLFMRNKHTFWQSTIYAPEWSELRSGRLADAFVPAMEETTDKSMEMSVAGRMGLWAAGSVDNWGERYARDNPSFDRLRQHSHQMVPNHALRQIIYKIASGARYINNFGFNQEYMSLAWELIGKGALYVPKREELLSLSPVHISMKEPDPIYRETSNNVKWTTFYDEEKDSIPYVFSRLNGTWPGAKTLPWDYSNYAADTKERRLDFIPKFPKGLVLITPVQQGKFKDEGTVRGTLADNMHPIYKDIMKEYITDGKNYYNANGEQVMAADSVRYRQIKNKIEEKSNLLPMTVSGEAAWVVAQSARKHLRLTLVDSGYLNPSNKVAKVKFNSVTPVAIVDVLSGETFSPDSNGVVEIPVLAGAFRFIDVKITEDLRNMQSSTL
What is the function of this protein?
Hydrolyzes lambda-carrageenan with inversion of anomeric configuration.  Does not hydrolyze iota- and kappa-carrageenans, agarose or porphyran.
What are the official names of this protein?
Lambda-carrageenase.
What are the subcellular locations of this protein?
Secreted.
Protein: O1616_CONAE
Sequence: MKLTCVLIIAVLFLTACQLTTGEQKDHALRSTDKNSKLTRQCTPVGGYCSRHYHCCSNHCIKSIGRCVAH
What are the official names of this protein?
Conotoxin ArMKLT2-0112.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AGFG1_HUMAN
Sequence: MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
What is the function of this protein?
Required for vesicle docking or fusion during acrosome biogenesis (By similarity).  May play a role in RNA trafficking or localization.  In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm.  This step is essential for HIV-1 replication.
What are the official names of this protein?
Arf-GAP domain and FG repeat-containing protein 1, HIV-1 Rev-binding protein, Nucleoporin-like protein RIP, Rev-interacting protein, Rev/Rex activation domain-binding protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasmic vesicle.
Protein: ANMK_PARMW
Sequence: MLCLGLMSGTSADGVDAVLARFQGAPDRPEWQLLSHHHSPYPAALRDELVRIGQGEARPAAALLDLAEAVTEHQALAARGADPDQRASLIGCHGQTLWHRPPSSDKRGASWQLLLAPLLAQLLARPVVHDFRATDLALGGQGAPLVPRADAALIGPGDGWRGVLNLGGIANLTLIPPRWGPQKQESVLGWDCGPANSLIDLAMEQFSDGQQLFDRDGAMAAAGRCDDGMIQRWLREPYFQLSPPKSTGRECFGQEDLRRRLQELESVERADAVATLTGFTAAVVAQDLDRLRADRSIHLLELLVAGGGCRNPVLMSELQRRCRGLAVRASDQIGLAAEAREALVFALLAWWHHRGHPGNAPAITGATREACLGVRVAPA
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: PYRF_SACD2
Sequence: MNIPDPQLVIALDFDTQESCLELVDQLDPTLCRLKIGKELFTSCGPKIVEKIQWKGFDVFLDLKFHDIPNTVAKAVKAAAELGVWMVNVHASGGEKMMLAAREALEGYQVKPLLIAVTVLTSMSDEDLKALGITVTAAEQVQRLAALAKQAQMDGVVCSAQEVVQLKASLGEEFKMITPGIRPSFAGNDDQTRIMTPEQALKAGSDYLVVGRPVTQADDPLRALEQIAAEMARASLGS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RUVA_SHELP
Sequence: MIGRLRGLLVEKQAPEVLIETGGVGYEVQMPLTSFYELPELNQEAVIYTHFVVREDAQLLYGFITKQERALFRLLIKTNGVGPKLALTILSGMTAGEFVKCVEHDDIATLVKLPGVGKKTAERLLVEMRDKLKSLMEASHGNEREFVLQSNYTPAPVVNTAEEDAISALLALGYKPAQASKAVSSVFEEGMDSETLIKASLKSML
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: EFTU_IDILO
Sequence: MSKEKFERSKPHVNVGTIGHVDHGKTTLTAAITTVLAKVYGGAAKDFAAIDNAPEEKERGITISTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLSRQVGVPFIVVFMNKCDMVDDEELLELVEMEVRELLSEYDFPGDDLPVIQGSALKALEGDEEWSKKIVELADALDNYIPEPERDIDKPFIMPIEDVFSISGRGTVVTGRVERGIVRTGDECEIVGMKDTTKTTVTGVEMFRKLLDEGRAGENIGALLRGTKRDDVERGQVLAKPGTITPHTKFEAEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGAVELPEGVEMVMPGDNLKFVVDLIAPIAMDEGLRFAIREGGRTVGAGVVSKIMD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGI2_BOVIN
Sequence: MSLRSHLSRLLRTQVHSVRKKSVHSVAVIGAPFSQGQKRKGVEYGPAAVRXAGLMKRLSDLGCHLKDFGDLNFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSGGYSCVTVGGDHSLAIGTISGHARHCPDLGVIWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSPSIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMEQTFDLLIGKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGIYITEEIHSTGLLSALDLVEVNPRLAVSEEEAKATASLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESESEERVRI
What is the function of this protein?
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis.  Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS).  Arginine metabolism is a critical regulator of innate and adaptive immune responses.  Seems to be involved in negative regulation of the survival capacity of activated T cells.  May suppress inflammation-related signaling in asthmatic airway epithelium.  May play a role in promoting prenatal immune suppression.  Regulates RPS6KB1 signaling, which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction.  Can inhibit endothelial autophagy independently of its enzymatic activity implicating mTORC2 signaling.  Involved in vascular smooth muscle cell senescence and apoptosis independently of its enzymatic activity.
What are the official names of this protein?
Arginase-2, mitochondrial, Arginase II, Type II arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL19_EHRRG
Sequence: MSNLLKEFNEQQIKLLSNREIPKFKSGDTLRVTMKIFDSAGERIQTFEGVCIKKRNNGLHSSFTLRKISYNESIQLQIFLYSPTIESIEVVKFGKVRRAKLYYMLSLFGKSARIKERIDRSKKSS
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ATP6_SALCH
Sequence: MASENMTPQEYIGHHLNNLQLDLRTFSLVDPQNPPATFWTLNIDSMFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHWLGLPATRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16_CYTH3
Sequence: MAVRIRLSKRGRRKLALYDIVVSDSRSPRDGKFIQKLGTYNPNTNPATVVLNDELTFDWVMKGALPTDTARTILSERGVMLKKHLQVGVDKGAITQEVADQKFSAWVSNKEASKTSNANALVSKKEADRKARLAAEVKIKEAKAEQVRAKKIVAENPVAAADLAEATDAPAEAAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.