PharMolix/UniProtQA huggingface dataset:
Protein: AFTB_CORGL
Sequence: MTFSPQRPEFETGKQPDPETEHAGDFFEETSSSAPRAASNGSSGPNYTLITTFLAALTAGIFAFWAGWTRKWISDDGLIVLRTVRNLLAGNGPVFNAGERVEANTSTLWQYCIYLVALVTDYRLEDIALWLALLFTTAASIIGVLGTAHLHRKRIAVLLPAGVIGYFSLSPARDFATSGLEWGLSLMWISIQWLLLVLWATSGKTSGKKASGAKTSNPIVNAGAITYALAFWSGLSWLVRPELAMYGGLTGVLLLLTAPRWRVVLGILVAALPLPAAYQIFRMGYYGLMVPHTAVAKSASDAVWGTGWEYVEDFTGPYNLWLGLALLLAAGALTVWKTDKHLAIPKGRLGLRTPGMAIALLVICALVHFLYVIRVGGDFMHGRMLLLPLFAILLPVSVIPVNVVDRGWQDLVALVLVFSTWVWSTVVFVQGHQWENTGQHVVDERDFWIDFTNRDEDHPPLYAEDFLTVDSMNDYAEVMRDQTLVNPTGQQLNILASSDPTTYSWITTPRVEGVEAGDLANLSPTVFHVNLGMTSMNAPLNVRVTDLIGLATPLAARQPRIEGGRIGHDKLMDLEWQVAESATPLAYTPGWLDTQKTYEARQALRHPELVHLFQTYREPMSYHRFVDNIKYALTTGRTLEISDNPEDLLKEFNPTPAEIQDGLETIAWPGEIKLDEPRGEPLYSSQ
What is the function of this protein?
Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the cell wall.  Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids.
What are the official names of this protein?
Terminal beta-(1->2)-arabinofuranosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AftB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ITPK1_MOUSE
Sequence: MQTFLKGKRVGYWLSEKKVKKLNFQAFAELCRKRGIEVVQLNLSRPIEEQGPLDVIIHKLTDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYMKDDRICSPPFMELTSLCGEDTMRLLEQNGLAFPFICKTRVAHGTNSHEMAIVFNQEGLNAIQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPESSSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVIDVNAFPGYEGVSEFFTDLLNHIATVLQGQSTGGAATEEVAPLRHNRLLAEPAGSLAGERTCSASPGCCGSMKGQDTPWKTETEAGNMGAGASAKLPHQRLGCTTGVSPSFQQHCVASLATKASSQ
What is the function of this protein?
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.  Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5.  This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not.  Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.  Also acts as an inositol polyphosphate phosphatase that dephosphorylates Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4.  May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium.  Probably acts as the rate-limiting enzyme of the InsP6 pathway.  Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.  Plays an important role in MLKL-mediated necroptosis.  Produces highly phosphorylated inositol phosphates such as inositolhexakisphosphate (InsP6) which bind to MLKL mediating the release of an N-terminal auto-inhibitory region leading to its activation.  Essential for activated phospho-MLKL to oligomerize and localize to the cell membrane during necroptosis.
What are the official names of this protein?
Inositol-tetrakisphosphate 1-kinase, Inositol 1,3,4-trisphosphate 5/6-kinase, Inositol-triphosphate 5/6-kinase, Ins(1,3,4)P(3) 5/6-kinase.
What is the protein family that this protein belongs to?
Belongs to the ITPK1 family.
Protein: AMPA_RICRO
Sequence: MLNVNFVNEASSTNQGLVVFIDEQLKLDSNLIGLDQQHHGLISKTIQNKLQFTGKYGQIKVIPSVIKSGEVRYLIIAGLGNEEKLTEAKIEELGGKILQHATSCKISTIGLKITNRISRFTSQTFASLVASGAFLASYRFDKYRTTLKEAEKFAVESIEIFTDNSTETAKLFEIKKLIAEAVFFTRDISNEPSNIKTPQVYAERIVDRLEPLGVDVDVIGEREMKNLGMGALLGVGQGSQNESKLVVMEYKGGSKDVPTIALVGKGVIFDTGGISLKPSSDMHLMRYDMGGSAAVVGTIIAVAGQKLPVNIVGVVGLVENMLSGNAQRPGDVVTTMSGQTAEVLNTDAEGRLVLADAVWYAQEKFKPKCVIDVATLTGAITIALGNTYAGCFSNNDELADKLIKVGEEVNEKLWRMPLHDEYDAMIHSDIADMANIANVPRAAGSCIAAHFIKRFIKDGVDWAHLDIAGVANSNKASALGPKGAVGYGVRLLEKFIKEYT
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_BACAN
Sequence: MLNPSIDSLLTKIDSKYTLVTVAAKRAREMQLANNCVVEKPVSHKCVGKALEEIDMEALSYVPSEDKVTE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RS16_MANSM
Sequence: MVTIRLSRGGAKKRPFYQIVVADSRCPRDGRFIERVGFFNPLAAGNAERLRIQLDRVNAWLEKGASLSDRVAALVKEAQKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL5_CORGB
Sequence: MTENYIPRLKTRYQDEIRTKLQGEFEFENVMQIPGVTKIVVNMGVGDAARDSKLINGAIEDLTAITGQKPQLRRAKKSIANFKLREGMPIGAKVTLRGDRMWEFLDRLLTVALPRIRDFRGLSDQQFDGHGNYTFGLTEQTMFYEIDVDKIDRPRGMDITVVTTAVTDDEGRSLLRELGFPFKGEDGNRQQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: YDIB_ECOLU
Sequence: MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLSFTYMAFEVDNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEFFDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVNDISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQVMGFGA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MATK_MENLI
Sequence: MEEFQRYFELDRYQQHDFLYPLIFQEYIYALAHDHGLNRSILLENAGYDKKSSLLIVKRLITRMYQQNHLIISANDSNQNPFLGHNKNLYSQMISEGFAVIVEIPFSLRLRSSLEGKEIVKSHNLQSIHSIFPFLEDKFLHLNYVLDILIPYPIHLEILVQTLRHWVKDASSLHLLRFFIHEYRNWNSLITPKRPSAHFSKRNQRLFLFLYNSHVCEYESIFIFLLTQSSHLRSTSSGVLLERIYFYGKLEHSVEVCAKDFKAILWLFKDPFIHYLRYQGKSILTSKGTSLLMNKWKYYLLNCWQCHFYVWSQPRRIYINQLSNHSLDFLGYLSSVRLNPSMVRSQMLENSFLIDNAIKKFDTIVPIIPMIGSLAKAKFCNVLGHPISKPVWADLSDSDIIDRFGRICRNLSHYHSGSSKKKTLYRIKYILRLSCARTLARKHKSTVRAFLKRVGSELLEEFFTEEEQVLSLTFPRAFSTSTSRGLYRRRIWYLDIICINDLANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYGB_SHEEP
Sequence: MAKPLTDGERRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATRRDYYLALAHTVRDHLVGRWIRTQQRYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHSPEGVRWLDTQVVLAMPYDTPVPGYKNDTVNTMRLWSAKAPNDFKLHDFNVGGYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTSFETFPDKVAIQLNDTHPALAIPELMRILVDVEKVDWGKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLDIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVRQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLAETIVERIGEDFLTDLSQLKKLLPLVGDEALIRDVAQVKQENKVKFSAFLEKQYGVKVNPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKKDPTQAFVPRTVMIGGKAAPGYHMAKKIIKLVTSIGDIVNHDPIVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAHEYYNHLPELQQAVDQINSGFFSPREPDCFKDVVNMLLNHDRFKVFADYEAYVACQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYARDIWGAEPPALQTPPPSLPRD
What is the function of this protein?
Glycogen phosphorylase that regulates glycogen mobilization.  Phosphorylase is an important allosteric enzyme in carbohydrate metabolism.  Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates.  However, all known phosphorylases share catalytic and structural properties.
What are the official names of this protein?
Glycogen phosphorylase, brain form.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
Protein: LRC14_MOUSE
Sequence: MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTLVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERLSTESMQAVILGLTARIHTQETEAGTQPLCRKHALRVLDMTGLLDDGVEQDPETMSMWDCTAAVARTCIAQQQGGTAEPGLSPVPVEIRVDLRVNRASYTFLREALQSSVASPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRIDLRFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFMCLRELSMGSSLLSGRLDQLLSTLQRPLESLELAFCALLPEDLRFLAQSSHAAHLKKLDLSGNDLSGNQLTPFQGLLQAVATTLLHLELTECQLADAQLLATLPTLTRCASLRYLGLYGNPLSMAGLKELLRDSVVQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTTDIYGRLAADYFSL
What is the function of this protein?
Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB.
What are the official names of this protein?
Leucine-rich repeat-containing protein 14.
What is the protein family that this protein belongs to?
Belongs to the PRAME family. LRRC14 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM258_CAEEL
Sequence: MDISKMNRYTAPVNFASLPLLTTFLCGVGLLLLATFTMIQVTSTKYNRNLLKELFIAATSSVFLGFGSVFLLLWVGIYV
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Transmembrane protein 258, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258, Oligosaccharyl transferase subunit TMEM258.
What is the protein family that this protein belongs to?
Belongs to the OST5 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VPAP_HHV7J
Sequence: MDRSNREHHSHRDHREHRDSKEPPTMAFHMKTWKTINKPLRAFAKLLRENTTVTFTPQPAIIIQSAKNHLVLKLIIHAECLYITDTDHFSTKTINNFVPLFDSFMGIISNPDVTKLYIQHDSDLYTRFLVTASDICAQASIPCVNGQEIVRESGKSALRIDLDHSTVTEILKWLAPVTKNKRSNKNEMTLAQIVVQVNPPSIKFLTDLNEIEFAHSGKVVFHDAKCMRLVLSSKNLQQAFSTCAVLKSSCSLRAIAGKEYKLFLIAKNVFLTVEAYLSQEQVKDDPKFERQAKTEEKGEKNHKVEEGNNFFCKQETQHKITSYMVPTKNGGTGTNFFNEKEDSESDDSAHFDYTPNSKRQRCGM
What is the function of this protein?
Accessory subunit of the DNA polymerase that acts to increase the processivity of polymerization.
What are the official names of this protein?
DNA polymerase processivity factor, Polymerase accessory protein, PAP.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae polymerase accessory protein family.
Protein: ARGJ_MYCLE
Sequence: MTKIVEIVNETRLLRAQGVTAPAGFQAAGITAGIKVSGAPDLALVFNEGPDYAAAGVFTRNKVKAAPVLWTQRVLSTGQLRAVILNSGGANACTGPAGFQDAHTTAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKVLAGVRAIVHKMAGGVTGGDDAAHAIMTTDTVPKQVALHNRNKWTVGGMAKGAGMLAPSLATMLCVLTTDAVVEPAALDQALRRATAHTFDRLDIDGCCSTNDTVLLLASGASGITPPQADLDDAVRHACDDLCAQLQADAEGVTKRVTVTVIGAASDDDALVAARMIARDNLVKTAVFGSDPNWGRVLAAVGMAPVALDPDRLCMSFNGAAVCIDGVGTPCARDVDLSTADIDITVDLRIGDSAATIRTTDLSHTYVEENSAYSS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_AGRFC
Sequence: MAHKKAGGSSRNGRDSESKRLGVKKFGGEAVIPGNIILRQRGTQWHPGANVGIGKDHTIFALTAGNVNFRTKANGRVFVSVAPKAEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: FLGI_BURPS
Sequence: MRPLVAARRRAAACCALAACMLALAFAPAAARAERLKDLAQIQGVRDNPLIGYGLVVGLDGTGDQTMQTPFTTQTLANMLANLGISINNGSANGGGSSAMTNMQLKNVAAVMVTATLPPFARPGEAIDVTVSSLGNAKSLRGGTLLLTPLKGADGQVYALAQGNMAVGGAGASANGSRVQVNQLAAGRIAGGAIVERSVPNAVAQMNGVLQLQLNDMDYGTAQRIVSAVNSSFGAGTATALDGRTIQLTAPADSAQQVAFMARLQNLEVSPERAAAKVILNARTGSIVMNQMVTLQNCAVAHGNLSVVVNTQPVVSQPGPFSNGQTVVAQQSQIQLKQDNGSLRMVTAGANLADVVKALNSLGATPADLMSILQAMKAAGALRADLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: RL23_CORGB
Sequence: MATIANPRDIIIAPVVSEKSYGLMEQNVYTFFVSTDANKTQIKIAIEEIFGVKVASVNTVNRAGKRKRSRTGFGTRKATKRAYVTLREGSDSIDIFNGSVA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: LEPA_COXBU
Sequence: MTTISQKFIRNFSIIAHIDHGKSTLADRFIQLCGGLSEREMKAQVLDSMDIERERGITIKAQSVTLNFKSQDGHFYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQTVATCYTAIEQGLVVLPVLNKIDLPQADPERAIQEIEDVIGIEAHDAIRVSAKEGRGVKELLEQLVVAIPPPVGDPEAPLQALIIDSWFDSYLGVVSLVRVKAGTLRKGDKIRVMSTGKDYYADQIGHFTPKRQPLEELSAGAVGFVVAGIKDIFGAPVGDTLTHAKQSAGSPLPGFKQVKPQVFAGLFPINSEEYEPFREALAKLRLNDAALFYEPESSEALGFGFRCGFLGMLHMEIVQERLEREYNLELITTAPTVSYEILAKQGEMLYVDNPSHLPEPGKIGEIREPIAVANILVPPTYLGAVITLCVEKRGVQKKLLYLSNQVSMTYEIPLSEVVLDFFDRLKSASRGYASLDYSFNHFQAADLVKLDILISGQKVDALATIVHRDLAYTRGRELTERLKDLIPRQMFEVAIQAAIGAKIIARTSVKALRKNVTAKCYGGDITRKRKLLEKQKAGKKRMKQVGKVAIPQEAFLAVLRVKNE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS16_CLOBB
Sequence: MAVKIRLRRMGCKKAPFYRIVVADSRSPRDGRFIEEIGYYNPITEPAEVKINEEKASKWLQDGAQPTDVVKKLFTQAGLSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SYS_SULIL
Sequence: MSWSILEFLRKNPEELKNNLKRRAIDVSLVDKAVELDKKWRQVLQEVERLRHQHNVLSSQIPKLSGEERKKKIEESKNLLKILEDKEKELEKIEVERDRLLSSLPNLVADDVPNGPDDSYNIPIKFWGKFKVYEGDVEEFLRQTKDANVNYEIIKWKPKGHAEMLEDVLHLGNTLKAAEIAGSRFYYLFNDIVWLDFALLLFAIDYITQQGYTLVLPPYMLRGEVIQSVIDLDTFKDAIYKIENEDLYLIATAEHSIAAMFFKEEIEKDKLPLKFAGISPAFRKEAGAANKDLKGIFRVHQFHKVEQFIFSTPEDSWKYHAELITNAESIFQQLELPYRIVNIASGDLGACAAKKFDLEVWMPAQAKFREMVSCSNCTDWQAFRMKIRYVDRKNNKRGYVHTLNSTAIASTRTITAILENYQREDGVVEVPKVLRKYLEIFPKAPKDYIYPLKNKII
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPM1_RAT
Sequence: MAASAWLEAGLARVLFYPTLLYTVFRGRVGGPAHRDWYHRIDHTVLLGALPLRSMTRRLVLDENVRGVITMNEEYETRFLCNTSKEWKNVGVEQLRLSTVDMTGVPTLANLHRGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHNWSPEEAIEAIAKIRSHISIRPSQLEILKEFHKEIAARAAKN
What is the function of this protein?
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) (By similarity).  PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle (By similarity).  Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production (PubMed:16039589).  Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues (PubMed:16039589).  Probably involved in regulation of insulin secretion in pancreatic beta cells (PubMed:16039589).  May prevent intrinsic apoptosis, probably by regulating mitochondrial membrane integrity (By similarity).
What are the official names of this protein?
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1, Protein-tyrosine phosphatase mitochondrial 1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: HXPB_ECOLI
Sequence: MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRNELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVERVIARAISLVEETRPLLPGVREAVALCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAKLGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQNDPRFVLADVKLSSLTELTAKDLLG
What is the function of this protein?
Sugar-phosphate phosphohydrolase that catalyzes the dephosphorylation of D-mannitol 1-phosphate and D-sorbitol 6-phosphate (PubMed:27941785).  Also catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate (2dGlu6P); this is a biologically important activity in vivo since it contributes to the elimination of this toxic compound and plays an important role in the resistance of E. coli to 2-deoxyglucose (PubMed:16990279).  To a lesser extent, is also able to dephosphorylate mannose 6-phosphate (Man6P), erythrose-4-phosphate, 2-deoxyribose-5-phosphate (2dRib5P), ribose-5-phosphate (Rib5P) and glucose-6-phosphate (Glu6P) in vitro (PubMed:16990279).
What are the official names of this protein?
Hexitol phosphatase B, 2-deoxyglucose-6-phosphate phosphatase, Mannitol-1-phosphatase, Sorbitol-6-phosphatase, Sugar-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: SYR_CLOTE
Sequence: MNYKELISERLSSIIELPIEDIEKLIEIPPKPEMGDFAFPCFQLAKTFRKAPNMIAEELKDKFDKSNFEKVENLGPYLNFFVDKSIFSKNVIEKILEEKDKYGASNEGKGRKALIEYSSPNIAKPFHVGHLFSTAIGNALYKIFTFEGYDCERLNHLGDWGTQFGKLIAAYKRWVDEEALEKEPIKELLRIYVKFHDEAEKDPALEEEGRLHFKRLEDGEEEEVKLWKKFRELSLKEFEKVYHMLNVEFDSYAGESFYGDKMDAVVEEIDEKGLLVESNGAKVVMLEDYNMPPCIIKKSDGATIYATRDLATAIYRKKTYDFYKSIYVVGLEQSLHFKQVFTTLKLMGHDWADDCTHIGFGLVRFTDRKLSTRKGEVIFLEDLLKESVDKTLEIINEKNSELENKEETAKKIGIGAVIFTYLKNNRERDIVFSWDEMLSFDGETGPYVQYSYARGKSILRKSGEIQGDVDYSKLNSKEEFELVKTLEGFNKSILQAIEKLEPSIVTRYVIEVAKAFNKFYNHNSILNAEDEEIKKARIKLVESTCQVIKNALNLLGIEVVEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUF1_CAEBR
Sequence: MNRQRLLKIWCLKKLGETHRCYSSAGDPTKLINFSEFTPEKIRNFGIVAHVDHGKSTLADRLLELCGAVPPGQQQMLDKLQVERERGITVKAQTAALKYQGYLLNLIDTPGHVDFSAEVSRSLAVCDGILLLVAANQGVQAQTIANFWLAFEKNIQIIPVINKIDLPGADIKSVETQLKNLFEFNSEECLHISAKSGLNVEKVLDAIVERVPAPTANVEAPFRAMIFDSYFDHFRGAIAHIVVKEGSVKKGDKIRSYQNDKSYDVSEVGVMRPEMVKCTEVRAGQVGYLVCNMRTVKEAVVGETLFAAETPKESVQSFAEIKGVKATVYAGLFPVETADYESLKQAVERLCLNDPSVTVTPDASKALGLGWRIGFLGVLHMEVFGARLSQEYDASVILCQPSVEYRAKIKDNENIRKKRYDGMEEVRILDPSKFPEESDVDSFLEPMVKVRMIVPNEMMGTVNGLCSECRGERGEISSIDTSRLMILWRLPLAEVAVDFFERLKKLTSGYASFDYEPDGWQETRLVKLTILINGKEVSEFSQILPAAMARDRAKTLVQRLKREIPRQQFEVTIKACIGSSTKALSQIVIQPMKRDFSQLLKGNFGGGGMERLNKKLSHQKKGKERMKMVGNIQIPKEAFLNVLKN
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PP153_ARATH
Sequence: MSSLMAIRCARTQNIVTIGSLLQLRSSFPRLSSQFHFSGTLNSIPIKHLSTSAAANDYHQNPQSGSPSQHQRPYPPQSFDSQNQTNTNQRVPQSPNQWSTQHGGQIPQYGGQNPQHGGQRPPYGGQNPQQGGQMSQYGGHNPQHGGHRPQYGGQRPQYGGPGNNYQNQNVQQSNQSQYYTPQQQQQPQPPRSSNQSPNQMNEVAPPPSVEEVMRLCQRRLYKDAIELLDKGAMPDRECFVLLFESCANLKSLEHSKKVHDHFLQSKFRGDPKLNNMVISMFGECSSITDAKRVFDHMVDKDMDSWHLMMCAYSDNGMGDDALHLFEEMTKHGLKPNEETFLTVFLACATVGGIEEAFLHFDSMKNEHGISPKTEHYLGVLGVLGKCGHLVEAEQYIRDLPFEPTADFWEAMRNYARLHGDIDLEDYMEELMVDVDPSKAVINKIPTPPPKSFKETNMVTSKSRILEFRNLTFYKDEAKEMAAKKGVVYVPDTRFVLHDIDQEAKEQALLYHSERLAIAYGIICTPPRKTLTIIKNLRVCGDCHNFIKIMSKIIGRVLIVRDNKRFHHFKDGKCSCGDYW
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g15690, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
What are the subcellular locations of this protein?
Mitochondrion.