PharMolix/UniProtQA huggingface dataset:
Protein: MATRX_IHNVO
Sequence: MSIFKRAKRTVLIPPPHLLSGDEERVTILSAEGEIKVTGRRPTTLEEKIYYSMNLAAAIVGGDLHPSFKSMTYLFQKEMEFGSTQEKVNFGSRKPAPQTTYQVMKAREIYLQTQPLEKKIPMQTYSVSTEGATITFTGRFLFSSSHVGCDDNRTKLAGLDGFTTSNSYQRVKDYYAQETALALTFAAPEKRGKEK
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein, Protein M2.
What is the protein family that this protein belongs to?
Belongs to the novirhabdovirus matrix protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=During bud formation, associates at the inner side of the plasma membrane of infected cells.
Protein: ISPH_CHLL2
Sequence: MKINLDRTSSGFCIGVQGTIHVAEEKLAAKETLFSLGDVVHNEVEVKRLENLGLTTIDEAVFKELQNTSVLIRAHGEPPETYATAERNKLDITDTTCPVVSKLQRTARLLCQLGYQVIIYGKHTHPEVIGINGHCSNRAVIIKHADLSDPEELKTLDTTIKTALISQTTMDVPGFYELKTNLEKRFAESDETAGKPWTAIRDIDITAAMTGIGTMPRTVFKDTICRQVSSRNKKLHDFALANSCVIFVAGRKSSNGQVLFGICRSANPRSYFIEDIEDLEDSWFRDNEGSPVESIGICGATSTPMWLLEKVAEFIDGRFNHRDA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: EFTS_SALDC
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNVAFILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVASLEGDVLGSYQHGARIGVLVAAKGADEELVKQLAMHVAASKPEFVKPEDVSADVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKSVGQLLKEHNADVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACNR_CORDI
Sequence: MPVVSNTELSMRRQEILEGARRCFAEHGYEGATVRRLEETVGKSRGAIFHHFSDKENLFLALAREDAARMAEVVAENGLVEVMRDMLAHPERHDWLATRLEITKMLRTDPSFRNRWIEHQRVLDDAVLERLQRNAHLGRMRDDVPIDVLHTYLETVLDGFISRLASGGDTDNLERVLDLVEESVRSSQPS
What is the function of this protein?
AcnR negatively controls the expression of the aconitase gene acn.
What are the official names of this protein?
HTH-type transcriptional repressor AcnR.
Protein: ASTA_YERPE
Sequence: MMKVRPVERRDLADIFELAGKTGVGMTSLPQNEQHLAARIERALNTWQGSLDPGEQGYLFVLEDSEQQKVVGVSAIEVAVGLNDPWYNFRVGTLVHASKALNVYKSVPTLFLSNDHTGYSELCTLFLDPDYRKDKNGPFLSKVRFLFIAAFRQYFSRKVIAEMRGYTDEQGRSPFWESVGRHFFSIEFAKADYLSGTGQKAFIAELMPKHPLYVDFLAEEARAVIGQVHPHTAPARAVLETEGLQYQGYVDIFDGGPTLEANTDDVRVVRDSSKRTVVIKDYDIEDYDIDPNGRLYLVANDHYHHFRAILMNTHLSDERLRLTPESAEALGVAAGDSVRIVSLFAPETKR
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: SURE_ERWT9
Sequence: MRILLSNDDGIHAPGIQTLAKSLREFAEVQVVAPDRNRSGASNSLTLETPLRTFNYPNGDIAVQMGTPTDCVYLGVNALMRPMPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGLPALAVSLDGYQHYDTAAAVTCSILKALLREPLRTGRILNINVPDLPLDQIKGIRVTRCGSRHPSSQAIAQQDPRGNTLYWIGPPGEKLDAGPDTDFAAVDEGYVSVTALHVDLTAHAAQQVVSSWLASAEVTREW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOX5_ARATH
Sequence: MIHTDIAEILCVKPKTTKKTKTMEEDVKKTTTMKIEGEVVVMKKNLLDFKDVMASLLDRVNELLGRRVSLHLISSHQPDPANEKRGRLGKAAHLEKWVTKIKTSVTAEETAFGVTFDWDESMGPPAAFVIKNHHHSQFYLKSLTLRGFPDGEGGATAIHFICNSWIYPNHRYRSDRVFFSNKAYLPSETPELIKELREEELKNLRGNEKGGEFKEWDRVYDYAYYNDLGAPDKGPDSVRPVLGGSPELPYPRRGKTGRKSTKSDPKSESRLALLNLNIYVPRDERFSHVKFSDFLAYALKSVTQVLVPEIASVCDKTINEFDSFEDVFHLYDGSIKLANGHTISKLRDVIPWEMFRELVRNDGERFLKYPLPDILKESRSAWRTDEEFAREMLAGLNPVVISRLQEFPPKSCLDSAKYGNQHSSIRTEHIESNMNGLNVQEALEQNKLYILDHHDALMPYLTRINSTNTKTYATRTLLLLQADGTLKPLAIELSLPHAQGESYGSVSKVFTPAEKGVEGSVWQLAKAYAAVNDSGYHQLISHWLQTHAVIEPFIIASNRQLSVVHPIHKLLHPHFRDTMNINALARHVLINSDGVLERTVFPSRYAMEMSSSIYKNWVFTEQALPKDLLKRGVAVEDPNSDNGVKLLIEDYPFAVDGLEIWSAIKTWVTEYCTFYYNNDKTVQTDTEIQSWWTELRTKGHGDKRHESWWPSMQTRDDLIETCTIIIWIASALHAAVNFGQYPYAGFLPNRPTVSRRFMPEPGTDEYAELEEDADVAFLKTITPQLQTLLGISIIEILSMHSTDEIYLGQRDSPNWTADDEPLEAFKRFGKELELIENNIIRRNNDKRFKNRTGPVNIPYTLLYPNTTDYTREGGITGKGIPNSVSI
What is the function of this protein?
9S-lipoxygenase that can use linoleic acid or linolenic acid as substrates.  Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure.  Function as regulators of root development by controlling the emergence of lateral roots (PubMed:17369372, PubMed:18949503).  9S-lypoxygenase-derived oxylipins may play an antagonistic role to ethylene signaling in the control of responses involving oxidative stress, lipid peroxidation and plant defense (PubMed:21481031).  LOX5-derived oxylipins may facilitate performance of green peach aphid (Myzus persicae) on foliage (PubMed:21481031).  9S-lypoxygenase-derived oxylipins are engaged during infection to control the balance between salicylic acid (SA) and jasmonate (JA) signaling to facilitate infection by the fungal pathogen Fusarium graminearum (PubMed:26075826).  9S-lypoxygenase-derived oxylipins activate brassinosteroid signaling to promote cell wall-based defense and limit pathogen infection (PubMed:26417008).  Does not seem to contribute to the oxidation of free fatty acids during seed aging (PubMed:28371855).
What are the official names of this protein?
Linoleate 9S-lipoxygenase 5, Lipoxygenase 5, AtLOX5.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
Protein: RL18_LEVBA
Sequence: MITKPDKNKTRQKRHIRVRNKISGTAERPRLNVFRSNKNIYAQVIDDVAGVTLVSASTLDSEVAGDNKTDQAKGVGELIAKRAIEKKITNVVFDRGGYLYHGRVQALAEAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL18_SULDN
Sequence: MKAKVLKSKIANRLKRKRRIRAKISGCASLPRVSVFRSNRYLSVQAINDATATTLTSLSSKATGHKANKEGGAALGAAFAAKLKEVGISQIVFDRNGYQYHGVIAAFGDALRENEIKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RS16_BIFAA
Sequence: MATKIRLKRMGKKFYAFYRVVIMDSRTKRDGRAIEEIGTYNPNTQPSTININSERAQYWLGVGAQPTEQVLNLLKITGDWQKFKGLDGAEGTLKTVEAGPDAAARVEAVEAQAQKLKAAKSEADAKAKAEAEAAATEEAPAEEPAAEAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: YRAR_ECOLI
Sequence: MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGVFNPHDPQLSDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLGAQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNETLFAPLFRLLPGNWKSIDARDVARVMLAESMRPEHEGVTILSSSELRKRAE
What are the official names of this protein?
Putative NAD(P)-binding protein YraR.
What is the protein family that this protein belongs to?
To yeast YER004W.
Protein: RL30_TREDE
Sequence: MAKRISVKLVKSTIGQKQPVCSTIRSLGLKKLNSTVEHDANPAVLGMVKRVAHLVEVKELN
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RL19_NEIMB
Sequence: MNLIQQLEQEEIARLNKEIPEFAPGDTVVVSVRVVEGTRSRLQAYEGVVIARRNRGLNSNFIVRKISSGEGVERTFQLYSPTVEKIEVKRRGDVRRAKLYYLRGLTGKAARIKEKLPARKG
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: D6KL2_ARATH
Sequence: MASTRKPSGHGAEVEAQKRSSSNSSTKSAKAETFEPMQLQRSVTNPRAVGIPESKRLPESFRKRSSDPAVCKPDFSSLSTVLEHVDSLTIDEKKTSGFGSVKTSSASAKLSDGTSSLGKTSGSAKLSGRLDFMESGKSSICRGSTSSDVSDESSCSSFSSTVNKPHKANDLRWEAIQAVRVRDGLLGLSHFRLLKRLGCGDIGSVYLSELSGTKCYFAMKVMDKTSLASRKKLLRAQTEREILQSLDHPFLPTLYTHFETEKFSCLVMEFCPGGDLHTLRQRQPGKHFSEQAVKFYIAESLLALEYLHMLGIVYRDLKPENVLVREDGHIMLSDFDLSLRCLVSPTLVKSAAIESDPLRKNVYCVQPACIEPSCIQPSCTVPTTCFSPRLFSSKSKKDRKPKNDTANQVRPLPELVAEPTDARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGRTPFKGSGNRQTLFNVVGQPLRFPETPVVSFAARDLIRGLLMKEPQQRLGFKRGATEVKQHPFFEGVNWALIRCATPPEIPKPVELEKGAVSVAEAPSSQKTAAGLVLNAQKGSDNYLEFDFF
What is the function of this protein?
Protein kinase that regulates the auxin transport activity of PIN auxin efflux facilitators by direct phosphorylation.  D6PK-mediated PIN phosphorylation promotes auxin transport in the hypocotyl and this is a prerequisite for PHOT1-dependent hypocotyl bending.
What are the official names of this protein?
Serine/threonine-protein kinase D6PKL2, D6 protein kinase-like 2, Serine/threonine-protein kinase AtPK5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Colocalizes with PIN1 to the basal (lower) membrane of root cells.
Protein: QUEC_PORGI
Sequence: MQREKDSLIVVSGGMDSVTLMYEKRASIALALSFDYGSKHNARELSFARLHAERLGVEHLIIPLDFIGQYFQSDLLLSGGDIPEGRYDEENMKSTVVPFRNGIMLAVAAGLAESRGLRRIYIANHFGDHAIYPDCRASFIRPMTEAVRCGTTNGVLIEAPYTDITKTDIARIGASLGIDYAETWSCYKGGVFHCGVCGTCVERREALHDAGIPDATEYEG
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: YUC5_ARATH
Sequence: MENMFRLMGSEDSSDRRRCIWVNGPVIVGAGPSGLATAACLREEGVPFVVLERADCIASLWQKRTYDRIKLHLPKKVCQLPKMPFPEDYPEYPTKRQFIEYLESYANKFEITPQFNECVQSARYDETSGLWRIKTTSSSSSGSEMEYICRWLVVATGENAEKVVPEIDGLTTEFEGEVIHSCEYKSGEKYRGKSVLVVGCGNSGMEVSLDLANHNANASMVVRSSVHVLPREILGKSSFEISMMLMKWFPLWLVDKILLILAWLILGNLTKYGLKRPTMGPMELKIVSGKTPVLDIGAMEKIKSGEVEIVPGIKRFSRSHVELVDGQRLDLDAVVLATGYRSNVPSWLQENDLFSKNGFPKSPFPNAWKGKSGLYAAGFTRKGLAGASADAVNIAQDIGNVWREETKRQKMRTRVGHRRCISVA
What is the function of this protein?
Involved in auxin biosynthesis.  Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in roots.
What are the official names of this protein?
Probable indole-3-pyruvate monooxygenase YUCCA5, Flavin-containing monooxygenase YUCCA5, Protein SUPPRESSOR OF ER 1.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
Protein: ADEC1_DESPS
Sequence: MQVSKDALKQLIRAGRGVIPASKVLEGGYLVNVMSNEVYLADVAIYEERIVAIGKVEEYKGPETEVIDVTGLYLLPGLIDGHLHSECSKLSITSFAKAVVPCGTTSIVSGLDEYISVSGLEGLQEVFKEVKKSPLKVFWGAPYKTPYTFPKSTVAFNFTEEVHQEVQQWPECFGVWETVREAVQEEDEDTLGALATAQNNRLPIFGCAPMARGKELNGYLCAGVRLDHESYDHEEVVEKMRNGMHMLIRESSVTHFLEENIRAVTEVNPYLARRVSFCTDDVTATDILEKGHMDNVVRQAIKAGVEPITAIQMATINSAEAYRIDHLVGSITPGKIADIVMVDSLEGFQVQAVLTDGKLVARDKKMSYELKAPARSSVLSCALKCATTTPEDFQYRVEIEQGTAEVLSMNVKGPFVRKRRDVTLQVANHIVQADTENDVLMVSVLERFGRNGNKSLAFCSGWKLKKGAMASSAAPDDNNIIVMGADASDMSIAVNHLIENGGGQVIVADGEILEFLALPVGGIVSDLEAEEIARQESLLTKAANSLGCDLPDPLMYMFFLPITAIPDYAITDVGPVDCIALTTFDPILALNPGK
What are the official names of this protein?
Adenine deaminase 1, Adenase 1, Adenine aminase 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: CBIT_METTH
Sequence: MIPDDEFIKNPSVPGPTAMEVRCLIMCLAEPGKNDVAVDVGCGTGGVTLELAGRVRRVYAIDRNPEAISTTEMNLQRHGLGDNVTLMEGDAPEALCKIPDIDIAVVGGSGGELQEILRIIKDKLKPGGRIIVTAILLETKFEAMECLRDLGFDVNITELNIARGRALDRGTMMVSRNPVALIYTGVSHENKD
What is the function of this protein?
Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
What are the official names of this protein?
Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating).
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
Protein: DMXR8_CRYX8
Sequence: MGFLYSQLFKSLPYPTGNYSGKTIVITGSNVGLGKEAARHYVRLGASKMILAVRSLDKGHDAKHDIEGTTKCADNVIEVWKLDMASYDSVQKFAARVVTELPRVDIFIANAGIAPGSYRTAEDNESSITVNVVSTFLLAALVMPKMKSTAATFKTRPTFTITSSDVHGHTTFPQKSAPDGQIIATVNDKATAEKIWDDMYPISKLLEVLGVRSIAEQNPASKFPVTINCVNPGLCHSELGRDFPTIGFWLIKFFLARTTEVGSRTLVHAGSQGEDSHGQYMSDCEIGTPAPFVTSVEGKETQDRVWNELVKKLDAIKPGVTSNF
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of the dimeric xanthones cryptosporioptides (PubMed:30996871).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase dmx-nrPKS (Probable).  The atrochrysone carboxyl ACP thioesterase dmxR1 then breaks the thioester bond and releases the atrochrysone carboxylic acid from dmx-nrPKS (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase dmxR15, and oxidized by the anthrone oxygenase dmxR16 to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by the oxidoreductase dmxR7 (Probable).  A-ring reduction by the short chain dehydrogenase dmxR18, dehydration by the scytalone dehydratase-like protein dmxR17 and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:30996871).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) dmxR6 then yields monodictylactone in equilibrium with monodictyphenone (PubMed:30996871).  In the case of the cryptosporioptides biosynthesis, monodictylactone is reduced at C-12 to an alcohol (by the short chain dehydrogenases dmxR12 or dmxR8) and hydroxylated at C-5 by dmxR9, yielding the electron-rich aromatic which could eliminate H(2)O to form the ortho-quinonemethide, followed by tautomerisation to paraquinone and complete the formal reduction to produce the 10-methylgroup (Probable).  Conjugate addition of C-4a-OH to the resulting paraquinone by the monooxygenase dmxR10 then gives cyclohexadienone, which is then reduced at C-5 by the short chain dehydrogenase dmxR3 to give the dihydroxanthone (Probable).  The 6,7-epoxide in the cryptosporioptides could be introduced by the cytochrome P450 monooxygenase dmxL3 (Probable).  The highly reducing PKS dmxL2 manufactures butyrate, which is further carboxylated by dmxL1 to form ethylmalonate (PubMed:30996871).  It is not yet clear whether the carboxylation occurs while the butyrate is attached to the ACP of dmxL2, but this unusual fungal metabolite could then be esterified to O-5 by the O-acetyltransferase dmxR13 (PubMed:30996871).  Finally, dimerization performed by dmxR5 gives the observed dimers cryptosporioptides A, B and C as the final products of the pathway (PubMed:30996871).
What are the official names of this protein?
Short chain dehydrogenase/reductase dmxR8, SDR dmxR8, Dimeric xanthone biosynthesis cluster protein R8.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MTNA_YERP3
Sequence: MQTLNTLDLQTTSLKIVNGQLWILDQQALPQRQEWLLADTVASLIEHIQALRVRGAPLIGLSASLLLALLAERGLSQALLEQALIALRESRPTAVNLMNNLARMQQALLQPNWVTAMAAEALRLVDEDRELCERIAQHGAALVKPGSNLLTHCNTGGLATAGIGTAIGVLLRAHQQGNLRQVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAQGQVDAIWVGADRIAANGDVANKIGTYSLAVLAHYHRIPFYVAAPHTTHDPDCPDGAAIPIEQRAASEVTGVSGGFGHCQWAPEDAAVYNPAFDVTPAALISGWVLDSGVITPEQVAAGFFQPHR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: PHOCN_MOUSE
Sequence: MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYENETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
What is the function of this protein?
May play a role in membrane trafficking, specifically in membrane budding reactions.
What are the official names of this protein?
MOB-like protein phocein, Class II mMOB1, Mob1 homolog 3, Mob3, Mps one binder kinase activator-like 3, Preimplantation protein 3.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=In a perinuclear punctate pattern. Associated with membranes and the Golgi stacks.
Protein: RP9_MOUSE
Sequence: MSSGAGSRRPREPPEHELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGFIKEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGREVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRENKRHEKDVRIQQLKQLLEDSTSDDDGSSSSSSGDREKRKKRKKKEKHKKRKKEKKKKKKRKHKASKSSESSDSE
What is the function of this protein?
Is thought to be a target protein for the PIM1 kinase.  May play some roles in B-cell proliferation in association with PIM1.
What are the official names of this protein?
Retinitis pigmentosa 9 protein homolog, Pim-1-associated protein, PAP-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAS_MAIZE
Sequence: MAPVPVSVSATLAPPPAAPPKTTSRSWERRAPADAAFAAASSVAGSAALLTLTPAAPAAALSKEDVAGSLTKAVDTVSQAIDVGGKAAEQVAAVLKALGEAVKPALPVLKSASDEALKLAAPVVSAASKQATEALQGAGVDPAPVLSVAKTAAEQSTKVIDAAKPVASAAVETITSLGPEDYVVAAGXAFLAYLLVPPVWSLVSSSLRGYKGDLTPAQALDKVTTQGYVLIDVRSEKDKAKAGLPQLPSNAKNKLVSVPLEDLPSKLKGMVRNAKKAEAEIAALKISYLKKIGKGSNVIIMDSYSDVAKTVAKTLDSVGFKNCWVMAGGFSGRKGWAQSRLGTDSYNLSVVEVVTPSRVIPAVAGRRTGTTAARIGTASSASRATTRKLLPGGVD
What is the function of this protein?
Modulates cytoplasmic Ca(2+) concentration and is crucial for proper stomatal regulation in response to elevated levels of external Ca(2+).  May function by regulating concentrations of inositol 1,4,5-trisphosphate (IP3), which in turn triggers release of Ca(2+) from internal stores.  May play a role in de-etiolation.
What are the official names of this protein?
Calcium sensing receptor, chloroplastic, Sulfurtransferase 3.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein; Stromal side.
Protein: DNAA_PROS9
Sequence: MQAANPIWAEVQQLLQKNLSKPSFETWIRPAKFNCFENGLLTLITPNNFTSDWLRKNYSETIEKAAEEICGHNVKVVFKSETNINNNSNSSDSVSQQNINSQSKSFSINQSNNLINRSKKSHSLNTRYVFKRFVVGPNSRMAHAAALAVAESPGREFNPLFICGGVGLGKTHLMQAVGHYRVEIDPDAKVLYVSTETFSSDLIQSIRKDGMHAFKNKYRSVDLLLIDDIQFLEGKEYTQEEFFNTFNALYEAGKQIVIASDRPPSQIPKLQERLISRFSMGLIADIQPPDIETRMAILQKKAEQERMNLPRDLIQFIAGRFSSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNSVGVVVTPKQVIKKVSDFFEVSAEELVSSSRRKPVSQARQIGMYLMRQGTDLSLPKIGDEFGGKDHTTVMYAIEQVEKKLSSDPNVASQVQKIKDLLQIDSRKNL
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUBP2_DROMO
Sequence: MLDKVKNVIVVLSGKGGVGKSTVSTQLALALRATGHKVGLLDIDLCGPSVPHLLGLEGRDIYQCDDGWVPIYTDESKTLAVMSIGFLLKNRNDPVIWRGPKKTMMIKQFLTDVKWEDLDYLIIDTPPGTSDEHITVMECMREVPCNGAIIVTTPQGVALDDVRKELTFCKKTGIKVLGIVENMSGFVCPHCSDCTNIFSSFGGAELAQLAQVPLLGTLPIDPRVGVLAGSTASVLNELADSSTAQVLRSIVQHLDGLTALPTSA
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAT_STRHY
Sequence: MSPERRPADIRRATEADMPAVCTIVNHYIETSTVNFRTEPQEPQEWTDDLVRLRERYPWLVAEVDGEVAGIAYAGPWKARNAYDWTAESTVYVSPRHQRTGLGSTLYTHLLKSLEAQGFKSVVAVIGLPNDPSVRMHEALGYAPRGMLRAAGFKHGNWHDVGFWQLDFSLPVPPRPVLPVTEI
What is the function of this protein?
Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA.  Can also acetylate demethylphosphinothricin but not PTT or glutamate.  This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance.
What are the official names of this protein?
Phosphinothricin N-acetyltransferase, PPT N-acetyltransferase, Phosphinothricin-resistance protein.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. PAT/BAR subfamily.
Protein: CERC_SCHMA
Sequence: MSNRWRFVVVVTLFTYCLTFERVSTWLIRSGEPVQHPAEFPFIAFLTTERTMCTGSLVSTRAVLTAGHCVCSPLPVIRVSFLTLRNGDQQGIHHQPSGVKVAPGYMPSCMSARQRRPIAQTLSGFDIAIVMLAQMVNLQSGIRVISLPQPSDIPPPGTGVFIVGYGRDDNDRDPSRKNGGILKKGRATIMECRHATNGNPICVKAGQNFGQLPAPGDSGGPLLPSLQGPVLGVVSHGVTLPNLPDIIVEYASVARMLDFVRSNI
What is the function of this protein?
This protease cleaves elastin and thus facilitates penetration of schistosome parasite larvae through elastin-rich tissue of the host.
What are the official names of this protein?
Cercarial protease, Cercarial elastase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.