PharMolix/UniProtQA huggingface dataset:
Protein: SPI1_MOUSE
Sequence: MLQACKMEGFSLTAPPSDDLVTYDSELYQRPMHDYYSFVGSDGESHSDHYWDFSAHHVHNNEFENFPENHFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHTGLSHQVSYMPRMCFPYQTLSPAHQQSSDEEEGERQSPPLEVSDGEADGLEPGPGLLHGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGRGGLAERRLPPH
What is the function of this protein?
Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites (PubMed:8079170).  Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions (By similarity).  Transcriptionally activates genes important for myeloid and lymphoid lineages, such as CSF1R (By similarity).  Transcriptional activation from certain promoters, possibly containing low affinity binding sites, is achieved cooperatively with other transcription factors.  FCER1A transactivation is achieved in cooperation with GATA1 (By similarity).  May be particularly important for the pro- to pre-B cell transition (PubMed:8079170).  Binds (via the ETS domain) onto the purine-rich DNA core sequence 5'-GAGGAA-3', also known as the PU-box (PubMed:2180582).  In vitro can bind RNA and interfere with pre-mRNA splicing (PubMed:8626664).
What are the official names of this protein?
Transcription factor PU.1, 31 kDa-transforming protein, SFFV proviral integration 1 protein.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPH_BUCBP
Sequence: MKILLENPRSFCVETKRALSIVNLALKTWGKLIYVNHKIVHNNYIINNLKLKGVIFSKNINSILESSKLMLSKHSVPNKIKKTTLEKKIFIIDATCPLVKKVHKKIHYKNKNTYNVILIENSQHPKIQGTLERYQKNLKNSIYIVKSKKYAIKLTIKNTRNSIITAQITLSSEKIYPIITILRKKFPAIINSHENNICYATINRKTAIKHISKKIRHYSCH
What are the official names of this protein?
Putative 4-hydroxy-3-methylbut-2-enyl diphosphate reductase homolog.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: LEXA_STAAC
Sequence: MRELTKRQSEIYNYIKQVVQTKGYPPSVREIGEAVGLASSSTVHGHLSRLEEKGYIRRDPTKPRAIEIVSDQTNDNINMEETIHVPVIGKVTAGVPITAVENIEEYFPLPEHLTSTHNSDIFILNVVGDSMIEAGILDGDKVIVRSQTIAENGDIIVAMTEEDEATVKRFYKEKNRYRLQPENSTMEPIYLDNVAVIGKVIGLYREM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: NLTP4_ORYSJ
Sequence: MARAANNKYVAAVMVVALLLAAPAASAVTCGQVVSMLAPCIMYATGRVSAPTGGCCDGVRTLNSAAATTADRQTTCACLKQQTSAMGGLRPDLVAGIPSKCGVNIPYAISPSTDCSRVH
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 4, LTP 4.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: YEEF_BACSU
Sequence: MKVFEAKTLLSEATDRAKEYKELRTQMVNLRKALKGVADLSDSEFSGKGASNIKAFYHDHVGVADQWIDYIDMKIAFFNSIAGAAEDKGLSDAYIEESFLEHELANANKKSKSIMSEQKKAMKDILNDIDDILPLDLFSTETFKDELADANDKRKKTLEKLDALDEDLKTEYALSEPNEQFIKSDFQKLQEATGKGKNATPIHYNAKAYRESDIHKKKGDIEKRTEAYLKIKKEEAKEREIEKLKERLKNYDYADADEFYEMAKTIGYENLTAEQQRYFTQIENTRELEAGFKGVAVGLYDSGKDAVVGLWDMVTDPGGTVEAITGAMAHPIKTYEAISAAIEESYQKDMVNGDTYSRARWVSYAVGTVVTSIVGTKGVGAVSKTGTAAKVTTKVKTAASKSATAQKAITVSKQTVDHIKQKVNTGIEVSKKHVKTKLNQIGDLTLADILPYHPRHDLVPAGVPYNAVNGVTLKEGLQKFAKVILPKPYGTSSSGRRTPAPHVPPVTVKYGEHFARWSRKKVLKPNIIYKTKEGYTYTTDNYGRITSVKADLQLGEAKRNQYAQTNAGKPQDRKPDDDGGHLIATQFKGSGQFDNIVPMNSQINRSGGKWYEMEQEWAKALSKKPPKKVAVQIEPVYSGDSLRPSYFDVTYKIGSRKEISVSIKNQPGG
What is the function of this protein?
Toxic component of one of 6 LXG toxin-immunity modules in this strain.  They promote kin selection, mediate competition in biofilms, and drive spatial segregation of different strains, indicating that LXG toxins may help avoid warfare between strains in biofilms.  Mediates intercellular competition during biofilm formation; disruption of the operon disadvantages the bacteria, but overexpression of the cognate immunity protein restores growth in competition with wild-type.  Overexpression alone in situ causes growth arrest but not cell lysis, a large decrease in chromosomal DNA content and the production of anucleate cells.  No effect is seen on rRNA.  Co-overexpression with cognate immunity protein YezG does not cause growth arrest.  The toxic effect is dependent on the epsA and tapA operons which are required for biofilm formation (PubMed:34280190).  Binds DNA in the presence and absence of YezG (By similarity).
What are the official names of this protein?
Toxin YeeF, DNase YeeF.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the LXG family.
What are the subcellular locations of this protein?
Cell membrane. Membrane raft. Note=Present in detergent- resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion (PubMed:22882210). Delivery to target cells requires the type VII secretion system (T7SS) and YukE (PubMed:34280190).
Protein: TATB_THIDA
Sequence: MFDIGFTELIVIGIVALVVVGPERLPKVARAAGHLYGRMQRYVSTVRSDISREMQLDEMRRVGQDFKQSVESAASGVEQQASVVDDYLRGEVDMLDKSVRNEPQNAQTPPQTADAEPAQPDVRQQTLPLEEPDQNRAAGEPSSTSTRPA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RIMP_MESFL
Sequence: MKNFASIKDEIQKIAESILKEYNLQIYEINNFFDFESDVLQILVEDITEPNKALDFDSIISSNEKLSDALENFPGLSEPYMLEVASAGIEKPIRSKDELVKAVNSYIHVELNQEKNTSSEIEGILLDFDVNKDTFRITYFLKGQKKKVDFKYEQVKFARYAVKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR93_HUMAN
Sequence: MSFPRGSQTQKIKHPIGTRKGPLEVPPPTEKDWPKDDEQDHVLVDPDEELDSLPQPYRMINKLVNLLFDQSWEIIEERNALREAESSQIQPTVYPPLGEIQLNKMPNCMAVSQDYVFIGGAKGFSIYNLYSAKQIYAWEKLKVDVTSIWATDLGNEILIAPVDEMGIIRLFYFYKEGLYLVKAINEVDDTSKQTTCIKMEISQGGDFAAFLLQGAGDIWLDVYKLPKETWLKKLEHPQLTSNPKKKVRQPQLNSLGPISADPLEMDANVSFKGDIKLSLPVYIMKIKPPKPVTGTTFKSPLEVFAKIKDCYGLGSGQNHFIKDSQWEQQAEIFNASYKKYLDREWEEEPLSTATFYFLLPSCLFAMPPEVKGPSGMACVLGIHWTRSHNFFLYSLNRTLKDKADPEGVWPCAAPIAVSQLSCSSSYLVLACEDGVLTLWDLAKGFPLGVAALPQGCFCQSIHFLKYFSVHKGQNMYPEGQVKSQMKCVVLCTDASLHLVEASGTQGPTISVLVERPVKHLDKTICAVAPVPALPGMVLIFSKNGSVCLMDVAKREIICAFAPPGAFPLEVPWKPVFAVSPDHPCFLLRGDYSHETASTDDAGIQYSVFYFNFEACPLLENISKNCTIPQRDLDNMAFPQALPLEKRCERFLQKSYRKLEKNPEKEEEHWARLQRYSLSLQRENFKK
What are the official names of this protein?
WD repeat-containing protein 93.
Protein: SYT_CHLL2
Sequence: MSDIQEQQASIAITLPDGTVKNVPSGSTGFDIALSIGKRLADDALAVTINGKPTDLHAPVLCDANIEIVTFDSQLGRDIFWHTASHIMAQAIEEIFPGSRFGAGPATEQGFYYDVASEHRFREEDLRAIEQKMLEIAKRNIMLQREEMKRVDAIAYFTSVRNDPYKVEILEDTLKHVDTVSLYHQGDFADLCTGPHLPSTSRLKAVLLSNISSSYWRGDSSRENMQRIYGIAFPSDKLLKEHIARQEEAKRRDHRKLGTELELFMLSPEIGSGLPVWLPKGAVIRSELETFLKEEQRKRGYLPVYTPHIGNIELYKRSGHYPYYSDSQFPPLTYHDEDGKQEQYLLKPMNCPHHHLIYSSKLRSYRDLPIRLTEFGTVYRHEQSGELNGLVRARGFTQDDSHIYCTPEQLVDEICNAIDLTQFVFGTLGFSEVQTRLSMHDPANQQKYGGTAEIWEQAEKDVREAADRMGIDYFIGVGEASFYGPKIDFIVRDALGRKWQLGTVQVDYVMPERFDLSYIGSDGQKHRPVVIHRAPFGSMERFIGVLIEHTAGNFPLWLAPVQAVVLPIAEEVHDYAKTIHTALLAAGIRVEIDTRNEKIGRKIREAEIGKIPCMIIVGQKERDSGEISLRRHRSGDMGSFTVPGLIDILKKEISERT
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_BRUSU
Sequence: MADPIFFKPSRELTIGDVADFTGASLRDPKLAPRSVERLASLKDAGEGALVFVEGKKNVSSLVGLKAAGVLCTESLADSVPSGIAVLVSRHPHRDFSAVGRMLFPASVRPESWLGETGISPAAFIHPTAQIEDGATVEAGAVIGSGVTIGAGTLIAATAVIGQNCQIGRNSYIAPGVSVQCAFIGNNVSLHPGVRIGQDGFGYVPGAAGLDKVPQLGRVIIQDNVEIGANTTVDRGSLDDTVIGEGTKIDNLVQIAHNVRIGRFCLVAAHCGISGSCVIGDQTMLGGRVGLADHLIIGSRVQVAAASGVMNDIPDGERWGGIPARPIKQWFRDIANIRSIGQSRKDASSDE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: MNMG_NITWN
Sequence: MTASFDVIVIGGGHAGCEAAAASARTGARTALVTHRFATIGAMSCNPAIGGLGKGHLVREVDALDGLMARIADAGGIQFRMLNRRKGPAVRGPRAQEDRKLYAAAMQAAIRETANLEVIDGEADDLIVSGGRIAGVRLTDGRRIKSAAVVVTTGTFLRGLIHLGEKSWPAGRVDEAPALGLSASFERIGFALGRLKTGTPPRLDGTTIDWAAVEMQPGDDPPEPFSVLTARITTPQIQCGITRTTPATHDLIRTNVHRSPIYSGQITSSGPRYCPSIEDKVVRFGDRDGHQVFLEPEGLDDATVYPNGISTSLPEEVQLAILATIPGLENVKMTRPGYAIEYDHVDPRELEPTLQTRRMRGLFLAGQINGTTGYEEAAAQGLVAGLNAALAAGGGDPVVFDRADGYLGVMIDDLVTRGITEPYRMFTSRAEYRLTLRADNADQRLTDRGIALGCVGAGRAAYHRAKMAALQAAKQGAMSLSVTPNEAARHGLSLNRDGHRRSAFELLSYPEIGWREVAAIWPELSAIDPAIAEHLEIDAKYDVYLKRQAADVEAFRRDEGLVLTEIDYSAVPGLSNEARNRLEKAQPLTVGQAGRLDGITPAALGILAAYLRREARQRTAASA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CORA_BLOFL
Sequence: MFNIFQLKNNCLFRMDSQDVISSINDVIWIDIIQSDDNESHDIQSISEQFKINFFEIKDILKNKRFCNSKQGVYIRSFFFSYNEDNQIDNSIVSFIICNNCLYTLRESGFSVFCIYQESLNNHVLNDGNAYELLLSLFEVKIDDLTDRIEHIYETLERLSFVIMDEQQIDGYDSILEDLAKLESMSWKIHINLLDTERALQFLVRKVKLPVTQKRHANGILRGITLLLPYNECIFQKVSFLTQSVMGLINIEQNRIIKIFSIVFLPPTLIASSYGMNFEFMPELKWSFGYPSAIFLMILTGLAPYLYFKYKKWL
What is the function of this protein?
Mediates influx of magnesium ions (By similarity).  Alternates between open and closed states.  Activated by low cytoplasmic Mg(2+) levels.  Inactive when cytoplasmic Mg(2+) levels are high (By similarity).
What are the official names of this protein?
Magnesium transport protein CorA.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_MUSSB
Sequence: MTNIRKTHPLTKIINNSFVDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYMFTETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAIHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLILMLMLLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFMILLVLMPIISIIENNMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYSC_SALPK
Sequence: MALHDENVVWHSHPVTVAAREQLHGHRGVMLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: AAC6_CITKO
Sequence: MNYQIVNIAECSNYQLEAANILTEAFNDLGNNSWPDMTSATKEVKECIESPNLCFGLLINNSLVGWIGLRPMYKETWELHPLVVRPDYQNKGIGKILLKELENRAREQGIIGIALGTDDEYYRTSLSLITITEDNIFDSIKNIKNINKHPYEFYQKNGYYIVGIIPNANGKNKPDIWMWKSLIKE
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring including amikacin, kanamycin and tobramycin.
What are the official names of this protein?
Aminoglycoside N(6')-acetyltransferase type 1, AAC(6')-I, Aminoglycoside resistance protein.
Protein: NOVA2_HUMAN
Sequence: MEPEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASGVLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSFALAAAANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYEQGVRASNPQKVG
What is the function of this protein?
Functions to regulate alternative splicing in neurons by binding pre-mRNA in a sequence-specific manner to activate exon inclusion or exclusion (PubMed:32197073).  It binds specifically to the sequences 5'-YCAY-3' and regulates splicing in only a subset of regulated exons (PubMed:10811881).  Binding to an exonic 5'-YCAY-3' cluster changes the protein complexes assembled on pre-mRNA, blocking U1 snRNP binding and exon inclusion, whereas binding to an intronic 5'-YCAY-3' cluster enhances spliceosome assembly and exon inclusion.  With NOVA1, they perform unique biological functions in different brain areas and cell types.  Uniquely regulates alternative splicing events of a series of axon guidance related genes during cortical development, being essential for central nervous system development by regulating neural networks wiring.  Regulates differentially alternative splicing on the same transcripts expressed in different neurons.  This includes functional differences in transcripts expressed in cortical and cerebellar excitatory versus inhibitory neurons where is required for, respectively, development of laminar structure and motor coordination and synapse formation.  Also the regulation the regulation of intron retention can sequester the trans-acting splicing factor PTBP2, acting as a variable cis-acting scaffolding platform for PTBP2 across various natural conditions (By similarity).
What are the official names of this protein?
RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAL1_HUMAN
Sequence: MTERPPSEAARSDPQLEGRDAAEASMAPPHLVLLNGVAKETSRAAAAEPPVIELGARGGPGGGPAGGGGAARDLKGRDAATAEARHRVPTTELCRPPGPAPAPAPASVTAELPGDGRMVQLSPPALAAPAAPGRALLYSLSQPLASLGSGFFGEPDAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR
What is the function of this protein?
Implicated in the genesis of hemopoietic malignancies.  It may play an important role in hemopoietic differentiation.  Serves as a positive regulator of erythroid differentiation (By similarity).
What are the official names of this protein?
T-cell acute lymphocytic leukemia protein 1, TAL-1, Class A basic helix-loop-helix protein 17, bHLHa17, Stem cell protein, T-cell leukemia/lymphoma protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEPF_LIMRJ
Sequence: MAANFLKSLFGEEDIDEQDGLYETSEQVSTPANTSNKVVSINSGRLNQMSQISLYEPRLYADVKQIASQLLEGHAVIVNFTQMDANVAARLVDFLNGTVFAIDGEMKRIGKEIFLCTPKNYEISGSLTSNLKNDGDKF
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: TFE_METJA
Sequence: MLNDPLVQEVLFNIFEGDEKGFEVIDVLLEKGETTEEEIAKELGVKLNVVRKLLYKLYDARLVDYKRWKDEDTNWYSYTWLPTLEKLPYVVKKKINELIKDLEKKLEFEKNNMFFFCPNCNVRFTFEEAMDYGFSCPGCGNMLQEFDNSELIKDLEEQIKFLKEELKNNPFLK
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: TRMB_STRPF
Sequence: MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIEVGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFEYSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: Y2818_BORBU
Sequence: MQKEITINYNEYTIGGIKGTFFGNSQYEANYRAKINGFIIDFFKIPISLKKKYELNIKALSDPNFSSTNIAMNCINTFKLIVDIVNMQTGENYDYDTFITKTDTEKMLKYGTKIIAALARHFDEQNKTNFNESYYEWEKGWIDKKWINYEPTAEEIKEIQIMNQKLNPLKLKHRKKNLNNGQIRLLQAINKIEDQSQQQATKSNSKTKKLKGNHGEKTKI
What are the official names of this protein?
Uncharacterized protein BBD18.
Protein: MACB_BRUME
Sequence: MAGAPLIRLEDICKTFHNGDLAVEVLHGITLDIRAGEFVAIMGASGSGKSTLMNILGCLDTPTGGRYLLDGEDVSTLNADELATLRRRTFGFVFQSYNLIPTSTAQENVEVPAIYAGTPAAERRKRAAALLNALKLGDRLDHRPSQLSGGQQQRVSIARALMNGGRIILADEPTGALDSQSGEDVMELLRSMHQQGHTVIVITHAREVAERADRLIEIRDGQILSDTTKRDIHTPEATLQPHEEIAGNGAHIADISEAVKMALRALRANIFRTVLTLLGIIIGVSSVVTMLAIGTGAQNTILDRINAMGTDLILVRPAMAGFRGSGSIATLVPQDADAILELPNVKSAVPEVTGTVTLRRGNVDYQSQANGTVPAFSLSEIVESRQRQLHHPERYRYLRPCGWLGTTVVKTLFPDGSNPVGDYILIQKIPFQIIGTLEPKGAGFGGSDQDDVVVVPLSTGNLRLFGQKYVRSITVQVKDSSLIDTTQNQIQSLLDQRHKKRDTMITNMSSVREDAAAMGKTMTVFLGSVAAISLLVGGIGVMNIMLVSVTERTREIGVRMATGARRRDILLQFIIEALSVSAIGGAIGVILGLGAAALASWAGLSVGYSFGPVLLAFACAFATGLIFGFLPARKASRLLPAVALSSE
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YG35_BPLLH
Sequence: MKLPIPYQMAVSTVHLKLTDQSAKKDRYGRTVPTWEGDITKCVVNMQTTYSGTNNDRQIVANGLIVMYAGYSNPIPTLTKENLGSKLTYQGLDYTVTSLNRFDQPGTEDLYCYELEVI
What are the official names of this protein?
Uncharacterized protein ORF5, ORF118.
What is the protein family that this protein belongs to?
Belongs to the Lactobacillus delbrueckii bacteriophages ORF5 protein family.
Protein: YVBH_VACCC
Sequence: MLDPSTGWVLMSLSFSSSLHLMSIDTSQSLIIARASSRVIAGESLPCPGDTLDNLAFTVFPSADSEMDLI
What are the official names of this protein?
Uncharacterized 7.4 kDa protein.
Protein: DLTA_STAAC
Sequence: MTDIINKLQAFADANPQSIAVRHTTDELTYQQLMDESSKLAHRLQGSKKPMILFGHMSPYMIVGMIGAIKAGCGYVPVDTSIPEDRIKMIINKVQPEFVFNTTDESFESLEGEVFTIEDIKTSQDPVIFDSQIKDNDTVYTIFTSGSTGEPKGVQIEYASLVQFTEWMLELNKSGNEQQWLNQAPFSFDLSVMAIYPCLASGGTLNLVDKNMINKPKLLNEMLTATPINIWVSTPSFMEMCLLLPTLNEEQYGSLNEFFFCGEILPHRAAKALVNRFPSATIYNTYGPTEATVAVTSIQITQEILDQYPTLPVGVERPGARLSTTDEGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKFENGQWFIQGRIDFQIKLNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKNIKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKIDRKKIAEVING
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.