PharMolix/UniProtQA huggingface dataset:
Protein: AROA_ALKMQ
Sequence: MLVTNKVEKLEGKMTVPGDKSISHRAIMLSSISKGTSRVKGFLRGEDCLSTISCFRDLGIDIEDRGTEIIIQGKGLHGLSEPLNVLDAGNSGTTIRLISGILAGQKFLTIVTGDASLRKRPMERIATPLRKMGAFIEGRDYGNLAPLVIRGGNLKGMDYASPVSSAQVKSAILLAGLYGEGDTIVREKITSRDHTEKMLKGLGANISTDQGVTRLGKSELYGQSIEVPGDISSAAFFMAGAAALPGSFLITEGVGLNPTRTGIIDVLRDMGGDIEIHNLRQSGGEEIGDIMIRGKKLYGTEIGKEIIPRLIDEIPVLAIIAATAEGKTIITGAEELKVKESNRITAMVTEMQKVGIKVTELPDGMEIEGGQVITGGRVESYGDHRIAMAMAICGLFAQEPIKINDSQCIDISFPNFEEKLKAVVR
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB2_STRPF
Sequence: MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFEKHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKHLGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKSAFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIVTHNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: B3A2_CAVPO
Sequence: MSGTPRRPASGADSFHKPEPEIVGPGTPGFPEQEEDDLHRTLGVERFEEILQEAGSRGGEELGRSYGEEDFEYHRQSSHHIHHPLSTHLPPDARRRKTPQGQVRKPRRRPGATPAGETPTIEEGEEDEDETSEAEGPVSHTDPSPASTPTSVQFFLQEDEGTDRKAERTSPSPPAQLPHQEAAPQATKKAQPDALVEEAIMVSGGTAGGDDGGASGRPLSKAQPGHRSYNLQERRRIGSMTGVEQALLPRVPTDESEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSSQSSREGREPGPTPRTRPRAPHKPHEVFVELNELLLDKNQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKEFSFPRNISAGSLGSLLGHHHTQGAESDPHVTEPLIGGVPETRLEVERERELPPPAPPAGITRSKSKHELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGPSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQMLKKREEQGRLLPPGVGLEPKSAQEKAFLQMVEAVGAVEDDDPLRRTGRPFGGLIRDVKRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTHDLIGVSELIMSTALQGVTFCLLGAQPLLVIGFSGPLLVFEEAFYSFCRSNELEYLVGRVWIGFWLVLSALLMVALEGSFLVRFGSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGCLASNSSEADGGKNTTWTEAAPTPGHGNTSSAEQAGVERPQGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVDYSIQDTYTQKLSVPSGFSVTAPEKRGWIINPLGEEEPFPVWMMVASLLPAILVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLLWLAAATVRSVTHANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSLVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVMYVKKVRTMRMHLFKALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTEREMKCLDANEAEPVFDEREGVDEYNEMPMPV
What is the function of this protein?
Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (By similarity).  Plays an important role in osteoclast differentiation and function (By similarity).  Regulates bone resorption and calpain-dependent actin cytoskeleton organization in osteoclasts via anion exchange-dependent control of pH (By similarity).  Essential for intracellular pH regulation in CD8(+) T-cells upon CD3 stimulation, modulating CD8(+) T-cell response (By similarity).
What are the official names of this protein?
Anion exchange protein 2, AE 2, Anion exchanger 2, Non-erythroid band 3-like protein, Solute carrier family 4 member 2.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PIMT_PSEFS
Sequence: MTSQRTRERLIQRLYEEGLSNAQVLEVIRRTPRHLFVDEALAHRAYEDTALPIGHNQTISQPYMVARMSELLLAAGPLDKVLEIGTGSGYQTAVLAQLVERVFSVERIKVLQDRAKERLVELNLRNVVFRWGDGWEGWPALAPYNGIIVTAVATDVPQALLDQLAPGGRLVIPVGSGEVQQLMLIIREDEGFSRHVLGAVRFVPLLNGPLA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLAP_XENLA
Sequence: MSQAGRDGGDSCYRLRCSLLGHELDVRGVARCPLWPGEGFVSVSRDRSSRLWVPDSPNRGFIELQRMSGHSNFVSCVCILPPSDLYPRGLIATGGNDQNICVFSLDSEKPLYTLKGHKNTVCSLSSGKFGTLLSGSWDTTGKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKSIKLWKAGRCEMTFLGHEDCVRGLATINDTEFLSCSNDASVRRWLITGECLQIYYGHTNYIYSVCLFPNSQDFVTTSEDRSIRIWRKGECTQTIRLPAQSVWCCCVLDNGDIVVGASDGIIRVFTESPDRIASIEEIQAFENELSKATIDPKTGDLGDIKIDDLPGRDHLNEPGTRDGQTRLIKEDGKVEAYQWSTGEGRWMKIGDVVGSSGATQQTSGRVLFEGKEYDYVFTIDVNESGPSHKLPYNLTEDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTAGQTPSTNLGYTDPLTGGGRYIPGSSSTDNNGADPFTGGNRYVPGSSLQSDYSAAAADPFTGKNAYRSSTAPTPNAYFPKTKPVTFDQANPSQILGKLKELNESAPEERKLPEEDLMQLDKLLSVAVNPSGGTVTAQQLDTLWRVVNWPEDLIFPALDVLRISIKNPTVNEMFCNEKEGSQFSSYLLQLMSPSGKQANQLLALRTFCNSFFCDPGSCLLMVERDNVLSKVIELKTVNNKNIHIALATLMLNYAICLHKVSDIEGKAQCLSAISSVIEVVQDLEAIFRLLVALGTLISGDTNAMQLAKSLGVDSQIKKYMSVTEPAKVNECCRLLLNML
What is the function of this protein?
Plays a role in protein ubiquitination, sorting and degradation through its association with VCP.  Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling.  May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.  Plays a role in cerebellar Purkinje cell development.  Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis.
What are the official names of this protein?
Phospholipase A-2-activating protein, PLA2P, PLAP.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PLAP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Synapse. Note=Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains.
Protein: AAS_SALEP
Sequence: MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLITPNHVSFIDGMLLALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLDPTKPMSIKHLVRLVEQGRPVVIFPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRIQLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTKTLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTPADKLWIFAHLLAPRLAQVKQQPEDAAIILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKGPNIMNGYLRVEKPGVLEVPSAENARGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSADKMHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YJGA_SHIDS
Sequence: MTKQPEDWLDDVPGDDIEDDEIIWVSKSEIKRDTEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIAQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: RF1_ALTMD
Sequence: MKESVVRKLEHLVERFEEVQALLGDPEVIGDQDKFRNLSKEFSQLEDVVAGFNAYQQAQENLASAQEMLNEDDAEMREMAQEEMKEAKGEIERLETELQVLLLPKDPNDDNNCFLEIRAGAGGDEAAIFAGDLFRMYSRYAESRGWRVELVNANESEHGGYKEVVANVSGDGVYGVLKFESGGHRVQRVPETESQGRIHTSACTVAVLPEIPESEAIEINPAELRIDTFRASGAGGQHVNKTDSAIRITHLPTGLVVECQDERSQHKNRAKAMSVLQARLNQIEEEKRAAEEASTRKSLVGSGDRSERIRTYNFPQGRVTDHRINLTIYRLDEVVEGDLKQLVDPILQEHQADLLASLSDE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IP3KB_HUMAN
Sequence: MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA
What is the function of this protein?
Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis.
What are the official names of this protein?
Inositol-trisphosphate 3-kinase B, Inositol 1,4,5-trisphosphate 3-kinase B, IP3 3-kinase B, IP3K B, InsP 3-kinase B.
What is the protein family that this protein belongs to?
Belongs to the inositol phosphokinase (IPK) family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Endoplasmic reticulum.
Protein: RPOC_BACFR
Sequence: MAFRKENKIKSNFSKISIGLASPEEILENSSGEVLKPETINYRTYKPERDGLFCERIFGPIKDYECHCGKYKRIRYKGIVCDRCGVEVTEKKVRRERMGHIQLVVPVAHIWYFRSLPNKIGYLLGLPTKKLDSIIYYERYVVIQPGVKAEDGIAEFDLLSEEEYLDILDTLPKDNQYLEDTDPNKFIAKMGAEAIYDLLARLDLDALSYELRHRAGNDASQQRKNEALKRLQVVESFRASRGRNKPEWMIVRIVPVIPPELRPLVPLDGGRFATSDLNDLYRRVIIRNNRLKRLIEIKAPEVILRNEKRMLQESVDSLFDNSRKSSAVKTDANRPLKSLSDSLKGKQGRFRQNLLGKRVDYSARSVIVVGPELRMHECGIPKLMAAELYKPFIIRKLIERGIVKTVKSAKKIVDRKEPVIWDILEHVMKGHPVLLNRAPTLHRLGIQAFQPKMIEGKAIQLHPLACTAFNADFDGDQMAVHLPLSNEAVLEAQMLMLASHNILNPANGAPITVPSQDMVLGLYYITKLRKGAKGEGLTFYGPEEALIAYNEGKVDIHAPVKVIVKDLDENGNIVDVMRETSVGRVIVNEIVPPEVGYINTIISKKSLRDIISAVIKACGVARTADFLDGIKNLGYKMAFQGGLSFNLGDIIIPKEKETLVQRGYEEVEQVISNYNMGFITNNERYNQVIDIWTHVNSELSNILMKTISSDDQGFNSVYMMLDSGARGSKEQIRQLSGMRGLMAKPQKAGAEGGQIIENPILSNFKEGLSVLEYFISTHGARKGLADTALKTADAGYLTRRLVDVSHDVIINEEDCGTLRGLVCTDLKNNDEVIATLYERILGRVSVHDIIHPQTGELLVAGGEEITEDIAKKIQESPIESVEIRSVLTCESKKGVCAKCYGRNLATNHMVQKGEAVGVIAAQSIGEPGTQLTLRTFHAGGTAANIAANASIVAKNNARLEFEELRTVDIVDETGEAAKVVVGRLAEVRFIDVNTGIVLSTHNVPYGSTLYVADGEVVEKGKLIAKWDPFNAVIITEATGKIEFEGVIENVTYKIESDEATGLREIIIIESKDKTKVPSAHILTEDGDLIRTYNLPVGGHVVIENGQKVKAGEVIVKIPRAVGKAGDITGGLPRVTELFEARNPSNPAVVSEIDGEVTMGKVKRGNREIIVTSKTGEVKKYLVPLSKQILVQENDYVRAGTPLSDGATTPADILAIKGPTAVQEYIVNEVQDVYRLQGVKINDKHFEIIVRQMMRKVTIDEPGDTRFLEQQVVDKLEFMEENDRIWGKKVVVDAGDSENLKAGQIVTARKLRDENSMLKRRDLKPVEVRDAVAATSTQILQGITRAALQTSSFMSAASFQETTKVLNEAAINGKIDKLEGMKENVICGHLIPAGTGLREFDKIIVGSKEEYDRILANKKTVLDYNEVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PAIP2_MOUSE
Sequence: MKDPSRSSTSPSIINDDVIINGHSHEEDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY
What is the function of this protein?
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs.  Its inhibitory activity on translation is mediated via its action on PABPC1.  Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1.  Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein-interacting protein 2, PABP-interacting protein 2, PAIP-2, Poly(A)-binding protein-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the PAIP2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDMY_MUSDO
Sequence: MNATDAESRKPENKPSSESSSSGSTSGSSDGEVSSKTYFKNNKSKVLSGQREVVLEVVRDLSYTICKEAEEKLVERFPRKDGSNEMLPKEDSINTNHNYTTDSDEHPVELTTKTEECKNTEKTKKKSFVRALSKDKQLSAYRSRSRSTRLSYSGHISRTHSVEKSLSRYKKSVLRNRRTSFGHGRDSSTTKRSVSRDKDNRLRRRIGSSRSHTRSHSRFRRSEKKLPSRSPRRIRSQERRHERRRSMSSDYERIALRRSEPIKRRDKDEFFKNNKKVSGDIKKGKGNDNGTVAELEAKITERQRKSLDILTSRTGGACLTPDKLRMIQAEITDKSSAAYQSIAREALKKYIHGYINKVNVDSVAVITRKLLKDNIVRGRGVLCHSIIQAQATSPKFTHVYAAMVAIINSKFPNIGELLLKRLVIQFKRAFGCNDKTVCLTSSHFIAHLVNQRVAHEILALEILTLLIESPTDDNVEVAITFLKECGMKLTEVSSDRVGGIFELLKNILHQGKLDKRVQYMIKVLFQVRRDGFKDHQSIIESLELVEEYAQFTHLLLLEDVTYPKDILNEFKFDDQYETNEEKYKALSKNILGSHASDSDGSFGSGSNSETALSDCDKGKNEVNDKYTSGDIIDETKPNLIALRRTIYLTLNSCLDYEECAQKLMKMQLKTCQQNEFCQILLDCCAEQRTYEKFYGLLTHRICKMNKSFIEPFKEIFKDICQTTHCLDTNRLRNISKFFAHLLFTDAISWDVLDCIKLTEDEAITSRCIFIKSFFQELVEYMGLYHFNKKLKTEVLAGTLAGLFPKDNPRNIRFSINFFTSIGLGGITNELCQLLKIAPKSAPSSSSSSSLSSELSAPSDDDSSSDSENKKKHKGKNKKMTKKKNPSKKKEETKKIVGKNKIAAKNKTIKRRTDKDNSSSKDNFLKSESSSNESISLDSLSSELFAPSSYSSSESSNDSESKEKHKGKNKKMTKKKNPSNKREKTKKKLSKNKKAPNKNTKKRMTEKDISSSESSISESKSLNCSASNQNENEKRKKRVTSKSRTKRVKMFKQCQWVDADNQRDIKRKKRAEYRYEPLVYRKRNEEYLKKGGPNCRKDNYGNRQNHEISQRHDSEIKRRREERKKRHHEKNHSREYKRSKLGPCQREYFLYMCCQFYYPCTFQCLCQNCHFTFYS
What is the function of this protein?
Male determiner protein (M-factor) that controls male somatic sexual differentiation.  Acts as a dominant factor that regulates the mRNA splicing of transformer (tra) and doublesex (dsx) transcripts and promotes expression of male splice forms of tra and dsx (By similarity).  Probably acts as a component of the spliceosome C complex required for mRNA splicing factor and exon-junction complex (EJC) assembly (By similarity).  Hinders eIF4AIII from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs (By similarity).
What are the official names of this protein?
Male determiner protein Mdmd(Y), Male determiner encoded on chromosome Y.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: RL13_MYCBP
Sequence: MPTYAPKAGDTTRSWYVIDATDVVLGRLAVAAANLLRGKHKPTFAPNVDGGDFVIVINADKVAISGDKLQHKMVYRHSGYPGGLHKRTIGELMQRHPDRVVEKAILGMLPKNRLSRQIQRKLRVYAGPEHPHSAQQPVPYELKQVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: Y2918_ACIBT
Sequence: MNTSIKNWPEQERPRERLLQQGPQSLSDSELLAIFLRSGSRQHSAVELARLLIQQFGSLNAVFDASYNELAQFNGIGATKYSQLLAVKELGRRYLDYHFSQTELSLHSSHLVLDYLRYELKGEKQEVFAVLCLDAELRKLHFKKLFFGSVQHCAVSVNQTLRYALQQHACQLVIAHNHPFGSPQPSPEDIKLTQQLEQACQLVEIRLLDHFIISPEGSFSFAEQQLLNPTSIAVQ
What are the official names of this protein?
UPF0758 protein A1S_2918.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: PSBN_MANES
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYFA_SALSV
Sequence: MSHLAELVANAAAAINQASDVAALDNVRVEYLGKKGHLTLQMTTLRDLPPEERPAAGAVINAAKEQVQQALNARKAELESAALNARLAAETIDISLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_COXB1
Sequence: MSLPTSLWDKCLGYLRDEIPPQQYNTWIRPLHAIESKQNGLLLLAPNRFVLDWINERFLNRITELLDELSDTPPQIRLQIGSRSTEMPTKNSHEPSHRKAAAPPAGTTISHTQANINSNFTFDSFVEGKSNQLARAAATQVAENPGQAYNPLFIYGGVGLGKTHLMHAVGNAILRKDSSKKVLYLHSERFVADMIKALQHNAMNEFKRFYRSLNALLIDDIQFFAGKDRSQEEFFHTFNALLDGQQQIILTCDRYPKEINGLEERLQSRFGWGLTVAIEPPELETRVAILMSKAEQLKVHLPHEVAFFIAKHIQSNVRELEGALKRVIANAHFTGQSITVDFTREALKDLLTLQARLITIENIQKTVAEYYKIKVADLLAKRRNRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKVKELLATSLDILEDYKNLMRILSG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H33_SPISO
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FMT_EHRRW
Sequence: MRIIFMGSPEFSVVALSSILNNTEHKIVGVYTRVPKPAGRGKVLTKTPIHTVAEMHGLTVYTPKSLKRIEEQDRIKELNPDVIVVVAYGLIIPKEVLSIPKYGCINIHPSLLPRWRGAAPIHYAILHGDSQTGVTIMQMNEGWDEGDILLQKKLSIDEQDNIETLSSKLSNLGGAMLVEVLNNIDNLVPVAQNEDNATYTNKIEDFHIDINETAEVACRRIRALYPRAFVFFNGKRLRILQASYYYDDNISSLKPSSILNSGMHIKCKGNTILVPLVVQMEGKTLCSIKDFVCGYNVKDYSIT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: NUOCD_CITK8
Sequence: MVNNMTDLTAQDAVWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHLISIDRNRDIMLKVALSENDLHVPTFTKLFPNANWYERETWEMFGITFDGHPHLTRLLMPPTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEALTFKPEDWGMQRGTENEDFMFLNLGPNHPSSHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDVVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLRDFLDWMPKRLDSYEKAALRNTILKGRSQGVAAYGKKEALDWGCTGAALRATGIDFDVRKSRPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPVAVRGSLVSDLIVHLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.