PharMolix/UniProtQA huggingface dataset:
Protein: KITH_HHV11
Sequence: MASYPCHQHASAFDQAARSRGHNNRRTALRPRRQQKATEVRLEQKMPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQGGGSWREDWGQLSGAAVPPQGAEPQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRPMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGEAN
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
Protein: RL31_DICDI
Sequence: MSSSEAVTREYTINLHKRLYGTTFKDRAPKAVKQVKLFAQKIMGTKDVRIDNKLNKFLWSQGIKNVPHRVRVTLSRKRNEDENATEKLYTVASLVIVKSFKGLQTKKVADN
What are the official names of this protein?
60S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: BIPA_BUCAI
Sequence: MHHSIRNIAIIAHVDHGKTTLLDKLLQQSGTFEEHEEKTERIMDSNDLEKERGITILSKNTSIKWNNYKINIVDTPGHADFGGEVERVMSMVDSVLLVVDALDGPMPQTRFVTKKAFKYGLNPIVVINKIDRIHSRPDWVVDQVFDLFVNLNASDEQLDFPIIYTSAVLGTSGTDYLNMQNNMIPLYESIIKYAPAPNVNSDQKFQMQISQLDYNSYLGVIGVGRVKQGSIKTNDKVTIIDRFGKHRSGKVNKVLNYFGLKRMEINQGYAGDIIAITGLNKLKISDTICHPDNLQPLPALSIDEPTVNMFFSVNTSPFSGKEGKYITSRQILERLKKETMHNVALQIKETKDPNIFSVSGRGELHLSILIENMRREGFELEVSRPKIIFREINGIQKEPFENVTLDIEEKNQGSVMQFIGIRKGELKNMIPDSKGRVRLEYILSSRALIGFRSEFMSITSGTGLCYSSFSHYDNLQNSNIGQRKNGVLISNSTGMAVGFSLFNLQERGKLFIGHGAQVYEGQIIGLHNRSNDLTVNCLTGKKLTNMRASGTDEAIVLTTAIHFTLEEAIGFINDDELVEVTPHSIRIRKFYLKENERKRANRNKKSI
What is the function of this protein?
A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation.  Binds GTP and analogs.  Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
What are the official names of this protein?
50S ribosomal subunit assembly factor BipA, GTP-binding protein BipA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Binds to ribosomes.
Protein: GRA8_GIBZE
Sequence: MGKPDIYNSSANVEKSPYYKAMQHRAPNVLTAVDKKAHGMRRRILSQGLSDSSTRAFGNTIKKHIERLCQKIEGHSDPNTQWSESYDMARWFSYLTFDIMADVVFGQPYNLLGNSEYRYVVDSIEGSNIRTGVLIQAPEAYTWRLDKRLFPASIRHRNTFVKFISSLVQERLTTKPLERDDIISHLLTAKDSETGQGFTKNEVAAESSTLIVAGTDTSSTALAATLFYLTQYPNMYRRAVAEVRSSFAKSQDVKLGRALNECVFTRACIEESMRLSPPAASALWRRVQVGGQTVDGHAIQAGCNIGVCIYAIHHNELYYPDPFVFNPDRWLQNDKQAQSAFSPFSVGPRSCIGKGFAMAELMLAVATILVKFDIRRAPGDQGCIGQGHLEGEDGRRMVDEYQLHDHVTAFKQGPVLQFRRRDTVVQSEAE
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of gramillins A and B, bicyclic lipopeptides that induce cell death in maize leaves but not in wheat leaves (PubMed:30395461).  The nonribosomal peptide synthetase GRA1 incorporates respectively a glutamic adic (Glu), a leucine (Leu), a serine (Ser), a hydroxyglutamine (HOGln), a 2-amino decanoic acid, and 2 cysteins (CysB and CysA) (Probable).  The biosynthesis of 2-amino decanoic acid incorporated in gramillins could be initiated by a fatty acid synthase composed of the alpha and beta subunits FGSG_00036 and FGSG_11656 (Probable).  The cytochrome P450 monooxygenase FGSG_15680 could hydroxylate the fatty acid chain (Probable).  Subsequent oxidation to the ketone by the oxidoreductase FGSG_00048 and transamination by aminotransferase FGSG_00049 could form 2-amino-decanoic acid (Probable).  On the other hand, FGSG_15680 could also be responsible for the HO-modified glutamine at the gamma-position (Probable).  Whether hydroxylation occurs on the fully assembled product or on the Gln residue prior to assembly into the gramillins requires further proof (Probable).  The thioredoxin FGSG_00043 could also be required for the disulfide-bond formation between CysA and CysB (Probable).  The specific involvement of the remaining proteins from the cluster is more difficult to discern, but could have broader regulatory (FGSG_00040 and FGSG_11657) or enzymatic functions (FGSG_00044 and FGSG_00045) (Probable).  The final C-domain of GRA1 does not possess the expected sequence of a termination CT domain, often implicated in macrocyclization and release of a cyclopeptidein fungal NRPs; and the thioesterase FGSG_00047 may act in concert with the terminal C-domain of GRA1 to catalyze the formation of the macrocyclic anhydride and release of the products (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase FGSG_15680, Gramillins biosynthetic cluster protein FGSG_15680.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: DCUP_AZOVD
Sequence: MTVLKNDRFLRALLKQPVDVTPVWMMRQAGRYLPEYRATRAKAGDFMSLCMNPELACEVTLQPLDRYPQLDAAILFSDILTVPDAMGLGLYFETGEGPRFRKVVSSPADIEALPVPDPERDLGYVMAAVRTIRRELNGRVPLIGFSGSPWTLATYMVEGGSSKDFRKSKAMLYDNPQAMHALLDKLARAVTAYLNGQILAGAQAVQIFDSWGGSLSSAAYQEFSLAYMKRIVDGLIREHEGRRVPVILFTKGGGLWLEAMAGSGAEALGLDWTCDIGDARARVGGKVALQGNMDPSVLYANPAAIRAEVARILARYGAGSGHVFNLGHGITPEVDPAHAGAFFEAVHELSAQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_HAHCH
Sequence: MTHYAISDLLKNKAEIGSEVTVKGWVRSRRDSKAGVSFIHVHDGSCFDAIQAVVAKELPNYDADVLRLTTGCSLIVTGTLVESPGQGQSCEIQATSVELVGLVDDPETYPVAKKRHTFEFLRGVAHLRPRTNAFGAVTRVRTTLSHAVHHFFYEQGFQWINTPILTASDCEGAGELFRVSTLDMANLPKTDSGKIDYSKDFFGKETFLTVSGQLNVEAYCLAMSKVYTFGPTFRAENSNTSRHLAEFWMIEPEIAFADLNDDADLAERFLKHMFKVVLDERSDDMAFFAERINPDVVSRLENMVDKEFVRIDYSEAIKILQNCGKKFEYPVQWGLDLQSEHERYLAETHVGAPVIVMNYPKEIKAFYMRLNDDDKTVAAMDVLAPGIGEIIGGSQREDRLDVLDARIGDMHHKEELWWYRDLRRYGSVPHAGFGLGFERLIAYVTGMENVRDVIPFPRTPDNAQF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CECA2_AEDAL
Sequence: MNFNKLFAIVLLAALVLLGQTEAGGLKKFGKKLEGVGKRVFKASEKALPVAVGIKALGK
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-A2.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y100_MYCPN
Sequence: MKEKIPFYNEKEFHDMVKKTKKGTFSGWYIIDKDNKSVEFSGSFNRQFKLNKPVIPVNTEYVTRKEFNEYKVSNDQRLTKIETTLAAQGEQINKLTQTVEKQGEQINQLVQVVLLHGEQINKLTQTVEKQGEQIKELQVEQKAQGEQIKAQGKQIKAQGKTLKSILQALGGINKRLDKIDPPK
What are the official names of this protein?
UPF0134 protein MPN_100.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: CTAA_MAGSA
Sequence: MTTMSRSFGRSDLANGAHRDVAVWLLACCFMVAVMVLLGGLTRLTHSGLSMVEWEPIRGIIPPLNDTDWQLFFEKYKQTPEYIKVNAGMSLAEFKGIFWLEYIHRVWGRLIGVVFGLPFLWLALSGRIGRAMVPRLAGVFLLGAAQGGMGWFMVKSGLVDNPAVSHYRLTAHLALAFLIHGWMFWLALDILADHRSTRRRAHGDVGAVRSWMLGLTGLVIVTLLFGGLVAGLKAGLIYNTWPLMDGAIVPKDLFPEGFHSLFEDIKTVQFGHRTLAEITIVVALVGWFRTRARLGTQTPAAIHAVGLMALLQVGLGIGTLVMVVPVWLASAHQMGAMALLTLCLWALHDLGRRI
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: APT_SHEON
Sequence: MAMNTETLSLIKQSIKTIPNYPKEGILFRDVTSLLENATAYKATIDLLVEHYRSKGFTKIVGTEARGFLFGAPLALGLGIGFVPVRKPGKLPRATISQSYELEYGHDSLEIHTDAITANDKVLVVDDLLATGGTIEATVKLIRQLGGEVQDAAFVISLPDLGGEARLTALGLELVKLCEFEGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TR08_CURCL
Sequence: MTKRESNTLAVLGCGMVFLVSLLDLANRLLGALGTAILSGILASMADQTADDSGRLFTNFTACVRRKETGAAVSDKISSHANANKVEILNKENLRGVKQADAVLLACQTHLYKALFDEPGMREALKKKLIISVLAGVTTAQLEAALGNGEDYFVIRAMPNIACFVRDSATVIEKPQRTFPEALLHVTDTVFKAVGNVFYIQPSAYDICTALCGSSPAFLAVFIDSMVDGAVAMGLSHKDAVDMAACTMRGAASLVLESGNPWTIRHQVASPGGSTMQGLLALEQGNVRSTISNALMVAAKEAKKLGSKENA
What is the function of this protein?
Pyrroline-5-carboxylate reductase-like; part of the gene cluster that mediates the biosynthesis of KK-1, a novel cyclic decapeptide compound with potent antifungal activity (PubMed:29686660).  The nonribosomal peptide synthetase (NRPS) catalyzes the elongation and cyclization of the decapeptide chain composed of 1 pipecolic acid residue (Pip), 1 alanine residue (Ala), 1 aspartic acid residue (Asp), 1 isoleucine residue (Ile), 1 glycine residue (Gly), 1 tyrosine residue (Tyr) and 4 valine residues (Val) (PubMed:29686660).  The Asp, Ile and 3 Val residues are N-methylated by the 5 methyltransferase domains from the NRPS (found in modules 3, 5, 6, 7 and 9), whereas the Tyr residue is O-methylated, probably by the cluster encoded O-methyltransferase OMT (PubMed:29686660).  The other tailoring enzymes from the cluster may be involved in further modifications leading to the synthesis of KK-1 (Probable).
What are the official names of this protein?
Pyrroline-5-carboxylate reductase-like protein TR08, KK-1 biosynthesis cluster protein TR08.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
Protein: POLS2_HUMAN
Sequence: MARHLLLPLVMLVISPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQHENASWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGRGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLRPRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGWKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGSRELFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGGSNLCPPELAKASGSPHAVYFLLLLTLLIQS
What is the function of this protein?
Serine protease.  Hydrolyzes the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln-Gly-Arg-AMC and, to a lesser extent, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Val-Leu-Lys-AMC.  Has a preference for substrates with an Arg instead of a Lys residue in position P1.
What are the official names of this protein?
Polyserase-2, Polyserine protease 2, Serine protease 36.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: NUSB_BACMK
Sequence: MKRRTARERAMQALYQMDITGELEPKVAVENTLDEGEETNEFLESLVVGFVDNKEEIDAAIRQNLKKWKLERISIVDRSILRVAVCEMKYMEEIPHNVTINEAIEIAKTFGDEESRRFINGVLSNIKDTL
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CHER_LISMO
Sequence: MIPDLEKDYLYFTRVVKRDLGLDLALYKETQMKRRILSFIVKKKYITFGEFFKHLKKDAVLLDEFISLITINVSSFFRNRNRWDALEKQVLPRLLEDSRGKLRVWSAACSSGEEPYSLAMMMERSVGTRHYDILATDLEPAILKRAVIGEYQSRQMEELSEQERHTAFVEKGDTYQILPKYRKSIRFRRHDLLTDYYEKGFDLIVCRNVLIYFTAEGKHQAYQKFAESLRRGGVLFIGGSEQILNPADYGLATLNNFFYIKT
What is the function of this protein?
Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
What are the official names of this protein?
Chemotaxis protein methyltransferase.
Protein: Y656A_HAEIN
Sequence: MNQSLFHHSKQQEYCPQCGAPLQIKQGKKGLFLGCSAYPECDYLRPLQRSEHKVLKTLDEICPKCGNLLQLKQGSFGMFIGCSHYPECDFVVREESESEEKITCPECKTGHLISRRGRQGKIFYGCDNFPKCKFSLPAKPYSVPCPTCHFPLSLLKSEDGEKQIFQCANKTCRHIFEQ
What are the official names of this protein?
Uncharacterized protein HI_0656.1.
What is the protein family that this protein belongs to?
To E.coli YrdD.
Protein: MTB6_BACSF
Sequence: MLQIASLFAGVGGIDLGFEQTGYFETVWANEYDKNAAITYQSNFKNKLIIDDIRNIKVEDVPDFDVLLSGFPCTSFSVAGYRKGFEDEKSGDLFFETLRLIVAKKPQVIFLENVKNLVGHDNGNTFKVIYEALESNGYHIKYQVLNAKDFGNIPQNRERIYIVGFRNIEHYKNFNFPMPQPLTLTIKDMINLSDKLDDRFYYTEDKCSFYSPLQEQMTSDETIYQWRRKYVRENKSNVCPTLTANMGTGGHNVPLVKTKHGIRKLTPRECFNFQGYPEDFILPELAPTHLYKQAGNSVVVPVIRRIAENIYKSML
What is the function of this protein?
A methylase that recognizes the double-stranded sequence 5'-GCNGC-3', methylates C-? on both strands, and protects the DNA from cleavage by the Bsp6I endonuclease.
What are the official names of this protein?
Type II methyltransferase M.Bsp6I, M.Bsp6I, Cytosine-specific methyltransferase Bsp6I, Modification methylase Bsp6I.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: QUEF_TOLAT
Sequence: MSHASPYENNPLLANLTLGQKTDYIAEYSPQLLQPVPRQLNRDALNLAGNLPFHGEDLWTLYEISWLNNKGKPVVAIGEARIDAGSINLIESKSFKLYLNSFNQTRFADLATVRHTLEQDLSKCAEGAIKVALYPLSEAAHHIGTFPGECIDDLDIVIDEYHFSSDWLEQAGDNHTIVEETLHSHLLKSNCLVTGQPDWGSVVIHYKGPRINREKMLRYLISFRQHNEFHEQCVERIFVDLQRHCQPEKLTVYARYTRRGGLDINPFRSNWETAPANMRLIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_GRABC
Sequence: MSFTANLDRIVARAEELRASLSEGLNGDSFAAASRELAELEPVVARIEELWAAERGLAEAEAMLADPDMRELAESEAEILREKLPSLTREIRIALLPKDEADERSAILEIRPAAGGDEASLFAAQLFSMYQRYAEIRGWRFEILEYDDTGLGGLKGGMAEITGRSVFARLKYESGVHRVQRVPATESQGRIHTSTVTVAVLPEAEDVDVQVDEGDLRIDVYRASGAGGQHVNKTESAVRITHLPSGIVVAMQEEKSQHKNRAKAMKILKARLYEQQRAALHASRAADRRAQVGTGDRSERIRTYNFPQGRVSDHRINLTLYKIDRVMLGELDDFVDALTAEDQAARLSAQEL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCJ13_RAT
Sequence: MDSRNCKVNAPLLSQRYRRMVTKDGHSTLQMDGAQRGLVYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYAVAEMNGDLEIDHDVPPENHTICVKHITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDLAVVAHKDGKPNLIFQVANTRPSPLTSVRVSAVLYQERENGELYQTSVDFHLDGISSEECPFFIFPLTYYHTITPSSPLATLLQHETPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHRFAALMTRGSKGEYQVKMENFDKTVPEHPTPVVSKSPHRTDLDIHINGQSIDNFQIAETGLTE
What is the function of this protein?
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.
What are the official names of this protein?
Inward rectifier potassium channel 13, Inward rectifier K(+) channel Kir7.1, Potassium channel, inwardly rectifying subfamily J member 13.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ13 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PKHA6_HUMAN
Sequence: MSNKTGGKRPATTNSDIPNHNMVSEVPPERPSVRATRTARKAVAFGKRSHSMKRNPNAPVTKAGWLFKQASSGVKQWNKRWFVLVDRCLFYYKDEKEESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGVRTYFFSAESPEEQEAWIQAMGEAARVQIPPAQKSVPQAVRHSHEKPDSENVPPSKHHQQPPHNSLPKPEPEAKTRGEGDGRGCEKAERRPERPEVKKEPPVKANGLPAGPEPASEPGSPYPEGPRVPGGGEQPAQPNGWQYHSPSRPGSTAFPSQDGETGGHRRSFPPRTNPDKIAQRKSSMNQLQQWVNLRRGVPPPEDLRSPSRFYPVSRRVPEYYGPYSSQYPDDYQYYPPGVRPESICSMPAYDRISPPWALEDKRHAFRNGGGPAYQLREWKEPASYGRQDATVWIPSPSRQPVYYDELDAASSSLRRLSLQPRSHSVPRSPSQGSYSRARIYSPVRSPSARFERLPPRSEDIYADPAAYVMRRSISSPKVPPYPEVFRDSLHTYKLNEQDTDKLLGKLCEQNKVVREQDRLVQQLRAEKESLESALMGTHQELEMFGSQPAYPEKLRHKKDSLQNQLINIRVELSQATTALTNSTIEYEHLESEVSALHDDLWEQLNLDTQNEVLNRQIQKEIWRIQDVMEGLRKNNPSRGTDTAKHRGGLGPSATYSSNSPASPLSSASLTSPLSPFSLVSGSQGSPTKPGSNEPKANYEQSKKDPHQTLPLDTPRDISLVPTRQEVEAEKQAALNKVGVVPPRTKSPTDDEVTPSAVVRRNASGLTNGLSSQERPKSAVFPGEGKVKMSVEEQIDRMRRHQSGSMREKRRSLQLPASPAPDPSPRPAYKVVRRHRSIHEVDISNLEAALRAEEPGGHAYETPREEIARLRKMELEPQHYDVDINKELSTPDKVLIPERYIDLEPDTPLSPEELKEKQKKVERIKTLIAKSSMQNVVPIGEGDSVDVPQDSESQLQEQEKRIEISCALATEASRRGRMLSVQCATPSPPTSPASPAPPANPLSSESPRGADSSYTMRV
What are the official names of this protein?
Pleckstrin homology domain-containing family A member 6, PH domain-containing family A member 6, Phosphoinositol 3-phosphate-binding protein 3, PEPP-3.
Protein: FTSI_ECO57
Sequence: MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAWLQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAGGISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIHLREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVIEDISSTDSQAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMANSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTIPYRINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLGLVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVDPPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYINKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPDALTTGDKNEFVINQGEGTGGRS
What is the function of this protein?
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
What are the official names of this protein?
Peptidoglycan D,D-transpeptidase FtsI, Penicillin-binding protein 3, PBP-3.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family. FtsI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PMM_WHEAT
Sequence: MAAARKDAGVLALFDVDGTLTAPRKEVTPEMLEFMKRLRENVTVGVVGGSDLVKISEQLGKSVITDYDYVFSENGLVAHKDGKLIGTQSLKTYLGDDQLKEFINFTLHYIADLDIPIKRGTFIEFRSGMINVSPIGRNCSQEERDDFEKYDKVHNVRPKMVSVLREKFAHLNLTFSIGGQISFDVFPQGWDKTYCLRYLEEFKEIHFFGDKTYKGGNDHEIFESDRTVGHTVTSPNDTVQQCKSIFLSE
What is the function of this protein?
Catalyzes the interconversion of mannose-6-phosphate to mannose-1-phosphate, the precursor for the synthesis of GDP-mannose (Probable) (PubMed:20920368).  GDP-mannose is an essential sugar nucleotide for the synthesis of D-mannose-containing cell wall polysaccharides (galactomannans and glucomannans), glycolipids, glycoproteins and the antioxidant L-ascorbate (Probable).  Can complement the yeast temperature-sensitive mutant sec53-6 (PubMed:17217471, PubMed:20920368).
What are the official names of this protein?
Phosphomannomutase, TaPMM.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic PMM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBM22_MOUSE
Sequence: MATSLGSNTYNRQNWEDADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPGVRMRFKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSFKDDMPKSDVNKEYYTQNMEREISNSDGTRPVGMLGKATSTSDMLLKLARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGINDPVADKLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSSP
What is the function of this protein?
Required for pre-mRNA splicing as component of the activated spliceosome.  Involved in the first step of pre-mRNA splicing.  Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle.  Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
What are the official names of this protein?
Pre-mRNA-splicing factor RBM22, RNA-binding motif protein 22.
What is the protein family that this protein belongs to?
Belongs to the SLT11 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nearly exclusively nuclear. Translocated from the nucleus to the cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol.
Protein: RL2_PORG3
Sequence: MGIRKLKPTTPGQRHKVIGAFDKITASTPEKSLVVGKKKTGGRNNTGKMTMRYIGGGHKQKYRFIDFKRTKDGIPATVKTIEYDPNRSSRIALLYYADGAKAYIIAPDGLEVGHTVMSGSEAAPEVGNALPLANIPVGTIIHNIELRPGQGAKMVRSAGSFAQLTSREGTYVVIKMPSGEVRRILSTCKATIGSVGNSDHALEKSGKAGRSRWLGRRPHNRGVVMNPVDHPMGGGEGRQSGGHPRSRKGLYAKGLKTRAPKKHSSKYIIERRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PSRP_ACIAD
Sequence: MSEGKLIKRSVFFISDGTAITAETLGHSLLAQFPNVDFDIHIMPYITTEEAAMNIVEEINQCQSRDGTLPLVFDTLVDPNVREIINTSKAVNLDVFEGLISKLEQVLGTPPTTLVGQTHAVTDSEYYKARIDAVHFALDNDDGALTRHYDKADIILIGVSRSGKTPTSIYLSLQFGIRVANYPLTEEDLDDNRLPKVLKEHKNKLFGLMIDAERLVAIRTERKANSRYASYSQCQMELRAVEGIFISEGIPYLNVSEMSIEEISTRILQMTGLKRRIG
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.