PharMolix/UniProtQA huggingface dataset:
Protein: COMP_BACSU
Sequence: MKNLIKKFTIAVIVLSILYISYTTYISMNGIIIGTKIHKNDKSQFMIEEISESSYGQFVGLRQGDIILKINKEKPSDKHLKWGYLSHINSLDILRSGKKIHLKDFDLVTLNRPYSFFLFVLPLFFYFLSIICIFYILKVNKKRRSFAAYILILLLLDISIAYISAGGPFRGHIINRYINLFTFISSPILYLQFIQRYLGEIGKTFLNRISFLYIIPIFNLGIEFFQDYLQVDIDFLATLNLVSFATLTLFSFSAIYLHLNKYKYAEHSFILKLLILTNTLSFAPFLIFFVLPIIFTGNYIFPALASASLLVLIPFGLVYQFVANKMFDIEFILGRMRYYALLAMIPTLLIVGALVLFDVMDIQMNPVRQTVFFFVVMFAVFYFKEVMDFKFRLKRFSEKFNYQDSIFKYTQLMRGVTSLQQVFKELKNTILDVLLVSKAYTFEVTPDHKVIFLDKHEVGPDWNFYQEEFENVTSEIGKIIEVNQGFLMKVGERGGSSYVLLCLSNINTPRLTRDEISWLKTLSFYTSVSMENVLHIEELMEHLKDLKQEGTNPIWLKKLMFAIEEKQRSGLARDLHDSVLQDLISLKRQCELFLGDFKKDDNPCREEVQDKLVQMNEQMSDVISMTRETCHELRPQLLYDLGLVKALSKLVAQQQERVPFHIRLNTGRFTASLDLDSQLNLYRIIQEFLSNAVKHSQATDVLIMLISIQNKIVLHYEDDGVGFDQEKNTEHSMSMGLSGIKERVRALDGRLRIETSEGKGFKADIEIEL
What is the function of this protein?
Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence.  Plays a role in sporulation, at least partly interchangeable with that of SpoIIJ.  Probably activates ComA by phosphorylation.
What are the official names of this protein?
Sensor histidine kinase ComP.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TIG_CLOBJ
Sequence: MNVKVENIEKNVVKLEITVDSEKFNEAVKKSFKKNAKRFNVPGFRKGKAPLNIIKKYYGEGVLFEDAINFCCEDTYPKAIEENNIKPVDYPQIDVVQIGEGKDFIYTAEVTTVPKVKLGEYKGVEVKKVSYEVEDEAVENELKSMQEKNARVSLKEEGEIEKGNIAIIDFKGYVDGKAFEGGEAKDYEIEIGSGTFIGDFEDQLVGLKKDESKEVNVSFPEEYGREDLNGKPATFEVTIKDIKVKELPALDDEFAKEVSEFDTLEELKSDIKDRMKKELSEKAKAEYEEAVVEAVGANAEIEIPKVMIEKEIENMVRDLEMRLKYQGLDLKSYYEFTNSSEEKVKEYMRETAEKRVKTDLIMQEIAKVEDIKATEEELKEKAMEVAKQYGQKDVEKTAELIANAQKAYLEIDIVNGKVLDLLVESSKEIA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RISB_LACPL
Sequence: MTTFNGKINGNGLKIGIAVARFNAFVTQQLLTGAQESLVQHGVNETDIDVAWVPGAFEIPLTVQKMITTKRYDGVIALGAVIRGATAHFDYVCSGVTTGIATVSLATDTPIMFGVLTTDTIEQAMDRAGFKSGNKGADCAVSLLETLDVQRAILKADLA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: AROB_NEIMA
Sequence: MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIITNETVAPLYLGTLQTALDAAGVSHFSIILPDGEAHKNWQTLNLIFDGLMQNRAERKTTLIALGGGVIGDMTGFAAATYQRGAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQPQAVLADLDTLHTLPARELSAGMAEVIKYGTLGDISFFEWLEQHMPELMALERAPLIQAVYRCCQMKADIVAQDETEQGIRAWLNLGHTFGHAIETEMGYGTWLHGEAVAAGCVLAARLSEQLGKISAADTARLAALLEAAGLPSAPPVFAFEKWLEHMSHDKKVSGGIMRFIGLNRLGEANITEITDTDILRRTLQPYL
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_PSEA6
Sequence: MVNNINQLGIEEILELLPHRYPFLLLDRVTDYTLGESITAYKNITFNEPCFTGHFPGKPIFPGVLILEALAQAAGVLGFKTAGNSDDLYLYAGIDKARFKHPVVPGDRLDMDVRLIKERRGIWKFHGVGSVDGKAVCEAEFMCAMRKL
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_NEIG2
Sequence: MDVQLPIEAKDIQKLIPHRYPFLQLDRITAFEPMKTLTAIKNVTINEPQFQGHFPDLPVMPGVLIIEAMAQACGTLAILSEGGRKENEFFFFAGIDEARFKRQVIPGDQLVFEVELLTSRRGIGKFNAVAKVDGQVAVEAVIMCAKRVV
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOC_DELAS
Sequence: MMTAIAIHPEVLRDVVAAALGDKARSVTVALGEVTVEVSAAQYLEAMQVLHTAPDCRFEVLVDLCGVDYSTYAEVGREGPRFAVVSHLLSISLNQRLRVRVFCTDDDFPVVASVTSVWAGANWFEREAFDLFGIVFDGHDDLRRILTDYGFIGHPFRKDFPLSGHVEMRYDPEQQRVVYQPVTIEPREITPRIIREDNYGGLH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS19_GLAP5
Sequence: MPRSLKKGPFLDLHLLKKVEKAVESGDKKPIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSDEMIGHKLGEFAPTRTYRGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MARHB_MOUSE
Sequence: MSDEGKKRSSRADSLEAEPPLPPPPPPPPPGESVLVPTSPRYRPPLPAPLERIVGSGEPPVELAPRRKGAGEPLPPLPPSLLPGDQEVTAAGDSCEGPRRLPEVKLPEAATGKGSPGEPEAGACREGERRGTGDQPETRSVCSSRSSSSGGGSDQRSGHQHQHHQPICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVTAIKMKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVHEGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLPLSALRNRNLVHPTQLTSPRFQCGYVLLHLFNRMRAHEDVSEDNGSGEVVMRVTSV
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.  May play a role in ubuquitin-dependent protein sorting in developmenting spermatids.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF11, Membrane-associated RING finger protein 11, Membrane-associated RING-CH protein XI, MARCH-XI, RING-type E3 ubiquitin transferase MARCHF11.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: RRF_ECO57
Sequence: MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDVQKLTDAAIKKIEAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
Protein: NADA_YERPP
Sequence: MSEIFDVNAAIYPFPARPVPLDTNEKAFYREKIKTLLKQRDAVLVAHYYTDPEIQALAEETGGCVADSLEMARFGNNHPASTLLVAGVRFMGETAKILNPEKKVLMPTLNAECSLDLGCPVDEFTAFCDSHPDRTVVVYANTSAAVKAKADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGSYVQKKSGADVLCWQGACIVHDEFKTQALARMKALYPDAAVLVHPESPQAVVDMADAVGSTSQLIQAAKTLPQKTLIVATDRGIFYKMQQACPDKELFEAPTAGEGATCRSCAHCPWMAMNGLRAIAEGLEQGGVMHEIHVDEELRQQALIPLNRMLDFANQLKLQVKGNA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VA725_ARATH
Sequence: MDRSVVPISLAPFQFLLVFWIFLTSVHTNPNKQQKTVVSLSLWWNSKNRIRGCVWFFFLLRVTRTMGQQNLIYSFVARGTVILVEYTEFKGNFTAVAAQCLQKLPSSNNKFTYNCDGHTFNYLVENGFTYCVVAVESVGRQIPMAFLERVKEDFNKRYGGGKATTAQANSLNREFGSKLKEHMQYCVDHPDEISKLAKVKAQVTEVKGVMMENIEKVLDRGEKIELLVDKTENLRSQAQDFRTQGTKIRRKMWFENMKIKLIVLGIIITLILIIILSVCGGFKCT
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
What are the official names of this protein?
Vesicle-associated membrane protein 725, AtVAMP725.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type IV membrane protein. Early endosome membrane; Single-pass type IV membrane protein.
Protein: NGLY1_MOUSE
Sequence: MASATLGSSSSSASPAVAELCQNTPETFLEASKLLLTYADNILRNPSDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSSKKVQFSQHPAAAKLPLEQSEDPAGLIRHSGNQTGQLPSLPSAPMVVGDSTILKVLQSNIQHVQLYENPVLQEKALTCIPVSELKRKAQEKLFRARKLDKGTNVSDEDFLLLELLHWFKEEFFRWVNNIVCSKCGGETRSRDEALLPNDDELKWGAKNVENHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYIIAFSKDEVVDVTWRYSCKHDEVMSRRTKVKEELLRETINGLNKQRQLSLSESRRKELLQRIIVELVEFISPKTPRPGELGGRVSGSLAWRVARGETGLERKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNNINISGWENGVWKMESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDTVSIRTSSQSFESGSVRWKLRSETAQVNLLGDKNLRSYNDFSGATEVTLEAELSRGDGDVAWQHTQLFRQSLNDSGENGLEIIITFNDL
What is the function of this protein?
Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation.  Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp.  Prefers proteins containing high-mannose over those bearing complex type oligosaccharides.  Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins.  Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.
What are the official names of this protein?
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase, PNGase, mPNGase, N-glycanase 1, Peptide:N-glycanase.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase-like superfamily. PNGase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK1_VIBPA
Sequence: MSAEKLYIEKELSWLSFNERVLQEAADKTVPLIERIRFLGIFSNNLDEFYKVRFADVKRRILINQERGGSDNSKRLLSKMQAKALKLNEQFDELYSELIREMARRRIFLVNEHQLDEAQEKWITKYFRKEVMPHITPLLMKDEIDVLQFLKDEYAYIAVELRKEDHSQYALIEIPTDHLPRFVMVPEQKGKRRKTIILLDNIIRYCLDELFKGFFDYDELAGYAMKMTRDAEYDLRNEIEYSLLEQMSAGVNQRLTAMPVRFVYEREMPQEMLDFLCSKLRISNYDNLIPGGRYHNFKDFIAFPNVGREYLENKPMPPMKCADFEGYANSFEAIKAKDILLYYPYHTFDHIGELVRQASFDPKVLSIKINIYRVAKDSRLMNSLIDAVHNGKNVTVVVELQARFDEEANIEWSKVLTEAGVHVIFGAPGLKIHSKLLMISRREGDDIIRYAHIGTGNFHEKTARIYTDFSLLTADQEITNEVRNVFGYIENPYRPVKFNHLMVSPRNSRTQIYRLIDNEIANAKAGKKAGLTIKVNNLVDKGIVTRLYAASNAGVKINMIIRGMCALVPGIEGVSENIRIISIVDRFLEHPRVVITHNDGDPQVYISSADWMTRNIDHRIEVAAPVRDPRLKQRIIDITNIHFTDTVKARLIDKEMSNSYVPRGNRKKVRSQVAIYDYLKNIEKQTRRQKSDVSDT
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: TRPC_PROMT
Sequence: MEIRRRPPNPSIKVANLEYAIPHPDSKPKNILEEIVWEKHLEVEIARKKVSLEDLKKKIKDLPKTKNFIDALRNSNSKPALISEIKKASPSRGIIREDFDAKMIGKMYQEGGANCISVLTDKKFFQGGFDVLVEVRKEIIIPILCKDFILYPYQLYQARAAGADAALLIAAILTDSDLKYLSKVAEHLGLTILVEVHDSEELERVLNINVFNLIGINNRNLKSFKTDLEVTKKLAENYANQIKENSITLVSESGLFNREDLDLVKSYGADAVLVGESLMSQEDILGGVKKLIGNL
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: Y2446_YERPG
Sequence: MYPVDLHMHTVASTHAYSTLHDYIAEAKLKNIKLFAITDHGPDMADAPHYWHFMNMRVWPRLVDGVGILRGIEANIKNLDGDIDCTGPMLDAVDLLIAGFHEPVFPPQDKAANTQAMIATMAQGNVHIISHPGNPKYPVDIPAIAQAAAKYNVALELNNSSFAHSRKGSEANCRAIAAAVRDAGGWLALGSDSHIAYALGIFEHCERIIAEVNFPQERILNVSPRRLLDYLEQRGRPVIPELAEL
What are the official names of this protein?
Probable phosphatase YpAngola_A2446.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: RS5_MALP2
Sequence: MEDIKTTTPEVKNEENKTSEVKEGKALEKNNKPHFVKANSSNVKPFERRSNPNNKKPFSKDGSGNKPNKIVKQSVTGLEEKIVGVKKISKTTKGGRNMRFSALAVIGDRKGNVGFGLGKSIEVPVAIRKALKSAKNNMYKVKMNKNFTLYHEVIGKHGAGKVLIKPAPKGTGVIAGGPIKVVLELCGFKDVYSKNLGKNTSLNMVRATIKGLQMQKSPKEYATLRDKTLKDIWE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: MA1B1_MOUSE
Sequence: MYPPPAPPPAPHRDFISVTLSLGESYDNSKSRRRRSCWRKWKQLSRLQRNVILFVLGFLILCGFLYSLHTADQWKALSGRPAEVEKMKQEVLPVLPAPQKESAEQEGFADILSQKRQRHFRRGPPHLQIRPPNTVSKDGMQDDAKEREAALGKAQQEENTQRTVISWRGAVIEPEQATELPYKRAEASIKPLVLASKIWKEPAPPNERQKGVIEAFLHAWKGYQKFAWGHDELKPVSKTFSEWFGLGLTLIDALDTMWILGLKQEFKQARKWVSENLDFQKNVDVNLFESTIRILGGLLSTYHLSGDSLFLTKAEDFGKRLMPAFTTPSKIPYSDVNIGTGFAHSPQWTSDSTVAEVTSIQLEFRELSRLTGIKKFQEAVEEVTKHIHSLSGKKDGLVPMFINTNSGLFTHPGVFTLGARADSYYEYLLKQWIQGGKKETQLLEDYVKAIEGIKAHLLRQSQPRKLTFVGELAHGRFSAKMDHLVCFLPGTLALGVHHGLPADHMDLARALMETCYQMNQQMETGLSPEIAHFNMYPRADHKDVEVKPADRHNLLRPETVESLFYLYRVTRDRKYQDWGWEILQSFNKYTRVPSGGYSSINNVQNSHKPEPRDKMESFFVGETLKYLYLLFSDDLELLSLDSCVFNTEAHPLPIWAPA
What is the function of this protein?
Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation.  It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2) (By similarity).
What are the official names of this protein?
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ER alpha-1,2-mannosidase, ER mannosidase 1, ERMan1, Man9GlcNAc2-specific-processing alpha-mannosidase, Mannosidase alpha class 1B member 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: H3_MASBA
Sequence: MARTKQTARKSTGGKAPRKAVATKARKTAPPVGGVKKPHRFRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIAALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ILVC_LISMF
Sequence: MTKVYYEDAVKNNALEGKTVAVIGYGSQGHAHSQNLRDNGNNVIIGIREGKSAESARNDGFDVYSVSEAAEKADVIMILLPDETQGETYENEIKPNLKAGNALVFAHGFNIHFDVINPPSDVDVFLVAPKGPGHLVRRTFVEGGAVPSLFAIYQDATGNARDTALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGATHLIQAGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMEKMRHSISNTAEYGDYVSGPRVVTADTKKAMKEVLTDIQNGNFAKSFIDDNKNGFKEFHRMRKEQQGHQIEKVGAELREMMPFVKPQH
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: VNFD_AZOCH
Sequence: MPMVLLECDKDIPERQKHIYLKAPNEDTREFLPIANAATIPGTLSERGCLLRRKLVIGGVLKDTIQMIHGPLGCAYDTWHTKRYPTDNGHFNMKYVWSTDMKESHVVFGGEKRLEQRMHEAFDEMPDIKRMIVYTTCPTALIGDDIKAVAKKVMKERPDVDVFTVECPGFSGVSQSKGHHVLNIGWINEKVETMEKEITSEYTMNFIGDFNIQGDTQLLQTYWDRLGIQVVAHFTGNGTYDDLRCMHQAQLNVVNCARSSGYIANELKKRYGIPRLDIDSWGFSYMAEGIRKICAFFGIEEKGERLIAEEYAKWKPKLDWYKERLQGKKMAIWTGGPRLWHWTKSVEDDLGIQVVAMSSKFGHEEDFEKVIARGKEGTYYIDDGNELEFFEIIDLVKPDVIFTGPRVGELVKKLHIPYVNGHGYHNGPYMGFEGFVNLARDTYNAVHNPLRHLAAVDIRDSSQTTPVIVRGAA
What is the function of this protein?
This vanadium-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase vanadium-iron protein alpha chain, Dinitrogenase 2 subunit alpha, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: RS11_LEPIN
Sequence: MADDKKSVKKEKKVKKKEKKIVPRGKVYITASFNNTIVTITDMAGNTISWSTSGAMGFRGSKKSTPYAAQIAAGNAAEKAMDSAGLQEVDVMVSGPGIGRESAIRSLVARGLNIKMIKDVTPLPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: GLGA2_GEOMG
Sequence: MKILQVASEVAPLAKTGGLADVVAALPKELRRMGHDVRVAIPFYKEVSSGNLPVRKARKSAEVALGGELHKGYLRQTALGEVPVYLVENRDLFGRDHLYGPPEGDYPDNPLRFAFFCRSVLQFLKRMDFRPDVIHCHDWQSALIPIILKYELGHDPFFNRTAVIFTIHNLAYQGVFPADALAQTGLDPSLFSVDRIEFYGRINLLKGAILAADAITTVSETYCHEILSPGQGCGLEGVLERRQADLAGILNGLDSEEWNPSLDRRIFRNYSSKSLAGKGADKRELQRELGLKAGASIPIIGMVGRIVEQKGIDLVIDLLPRFAAEELQLVILGTGDLRLMHQLHEFRNKGVKNVSINLGFKEPLAPKIYAGCDMFLMPSRFEPCGLSQLIALSYGTVPIVRRTGGLADTVIDVTANPREGNGFSFTEFSADACWDAVQRALAAYRDREGWRKIMRRGMLRDVSWRSAAGKYEELYRTCADNRRG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase 2, Starch [bacterial glycogen] synthase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: LGT_COREF
Sequence: MDVMTLAAIPSPPQGVWYLGPLPIRAYAMCIIAGIIVAIWLTRKRYAARGGNPEVVLDAAIVAVPAGIIGGRIYHVITDNQKYFCETCDPVDALKITNGGLGIWGAVILGGLAVWAYFRYKKIPLAPFADAVAPGVILAQAIGRLGNWFNQELYGAETDVPWALEIYYRVDENGRFAPVTGVSTGEVIATVHPTFLYEMLWNLLIFGLLIWADRRFRLGHGRVFALYVAGYTLGRFWIEQMRTDEATMVFGMRINTLVSAVVFILAVIVFLRLGKGREAPAEVDPAYHAAQAERDDTETAGLDATTGTVPGDSPETTGKKRK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTH_CLOB6
Sequence: MYLVVGLGNIGKEYKQTRHNIGFDVVDIIAEKYNIEINRQKFKGSYGEGRIGNEKIILLKPSTYMNLSGESVIEAANFYKIDKENIIVIYDDMSIDIGKLRVRGKGSAGGHNGIKNIIQHLNSDIFPRVRVGIGQPDENVVNYVLGKFSKDQREIIEKVLAMSAKACISIVEDGVTEAMNKYNGVKIEV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_ECO5E
Sequence: MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: LTR2A_XENLA
Sequence: MLRPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDKNGHQAFNEDNLKLILMDCMEGRVAITRVSNLLLCMYAKETVGFGMLKAKAQALVYYLEEPLNQVSSA
What is the function of this protein?
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids.  As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids.  Adapter protein that may regulate the MAP kinase cascade (By similarity).
What are the official names of this protein?
Ragulator complex protein LAMTOR2-A, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2-A, Roadblock domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the GAMAD family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side.