PharMolix/UniProtQA huggingface dataset:
Protein: EFG_MYCBP
Sequence: MAQKDVLTDLSRVRNFGIMAHIDAGKTTTTERILYYTGINYKIGEVHDGAATMDWMEQEQERGITITSAATTTFWKDNQLNIIDTPGHVDFTVEVERNLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYDVPRICFVNKMDKIGADFYFSVRTMGERLGANAVPIQLPVGAEADFEGVVDLVEMNAKVWRGETKLGETYDTVEIPADLAEQAEEYRTKLLEVVAESDEHLLEKYLGGEELTVDEIKGAIRKLTIASEIYPVLCGSAFKNKGVQPMLDAVVDYLPSPLDVPPAIGHAPAKEDEEVVRKATTDEPFAALAFKIATHPFFGKLTYIRVYSGTVESGSQVINATKGKKERLGKLFQMHSNKENPVDRASAGHIYAVIGLKDTTTGDTLSDPNQQIVLESMTFPDPVIEVAIEPKTKSDQEKLSLSIQKLAEEDPTFKVHLDSETGQTVIGGMGELHLDILVDRMRREFKVEANVGKPQVAYKETIKRLVQNVEYTHKKQTGGSGQFAKVIINLEPFTGEEGATYEFESKVTGGRIPREYIPSVDAGAQDAMQYGVLAGYPLVNLKVTLLDGAYHEVDSSEMAFKIAGSQVLKKAAALAQPVILEPIMAVEVTTPEDYMGDVIGDLNSRRGQIQAMEERAGARVVRAHVPLSEMFGYVGDLRSKTQGRANYSMVFDSYSEVPANVSKEIIAKATGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDP_ECOK1
Sequence: MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIISTTEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQTWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGTRKRTHLASNLAEFLNQLKPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: TGT_SALG2
Sequence: MKFELDTTDGRARRGRLVFDRGIVETPAFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRDRFDSLGNKNALFGIIQGSVYEDLRDISVKGLVEIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKSDTSPLDAECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTEFYQRQGRPVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RAG3B_ARATH
Sequence: MSTRRRTLLKVIILGDSGVGKTSLMNQYVNNKFSQQYKATIGADFVTKELQIDDRLVTLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVNHLKSFESLDNWHNEFLTRASPRDPMAFPFILLGNKVDIDGGNSRVVSEKKAREWCAEKGNIVYFETSAKEDYNVDDSFLCITKLALANERDQDIYFQPDTGSVPEQRGGCAC
What is the function of this protein?
Intracellular vesicle trafficking and protein transport.  Functions in autophagy.  Involved in xylem and tracheary element differentiation.
What are the official names of this protein?
Ras-related protein RABG3b, AtRABG3b, Ras-related protein Rab75, AtRab75.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ATP5J_DROME
Sequence: MLSQSLLSGMRVLRTEARRNFGIVAPALNKASDPIQQLFLDKVREYKQKSAGGKLVDSNPDIERELKTELDRVAKQFGSDGKTDMLKFPEFQFPDVKVDPITQAPQ
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
What are the official names of this protein?
ATP synthase-coupling factor 6, mitochondrial, ATPase subunit F6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase subunit F6 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: NNRE_DROPE
Sequence: MVKYLSQSEAIELDLDLFEMFHVGQLMELAGLSCADAVAECFPAQTHPRVLVVCGPGNNGGDGLVCARHLSLMGYQPTVYYPKPTLMSLYENLTNQCHHMEIPSVKKCPSLSDAEEDYDLILDALFGFGFKPPVREDFVPLVKMMQETKVPIASVDIPSGWDVEKGKQSECDFEPKLLISLTAPKLCAEHFKGEHHYLGGRFVPPALQRKYQLNLPDYGSKLVVRL
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: RS19_TREDE
Sequence: MSRSVKKGPFIAKSLFKNVNEMNRSGKKKPIKTYSRCSTIIPEMVGNTISVHNGKTWIPVYITENLVGHKLGEFAPTRTFRKHANSDKKVGK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MANB_KLEPN
Sequence: MTQLTCFKAYDIRGELGEELNEDIAYRIGRAYGEFLKPGKIVVGGDVRLTSESLNVALARGLMDAGTDVLDIGLSGTEEIYFATFHLGVDGGIEVTASHNPMNYNGMKLVRENAKPISGDTGLRDIQRLAEENQFPPVDPARRGTLRQISVLKEYVD
What is the function of this protein?
Involved in the biosynthesis of the K2 capsular polysaccharide biosynthesis.
What are the official names of this protein?
Phosphomannomutase, PMM, ORF17.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ATPD_RHOPT
Sequence: MASEDPSVSGVSGRYATALFELARDEKSIDAVTADLDKFSAMLAGSPDLVRLVRSPVFASEVQGKALAAVLDKAGITGISANFLKVLAANRRLFVVADVIRAYRALVAKFKGEATADVTVAEKLSDKNLEALKAALKSVTGKDVALNINVDPAIIGGLVVKLGSRMVDSSLRTKLNSIKHAMKEAG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MSD2_AMAFU
Sequence: MSDINATRLPVWIGCSPCVGDDCIALLTRGEG
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:24613547).
What are the official names of this protein?
MSDIN-like toxin proprotein 2.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: MNME_FRATW
Sequence: MYTKDTIVAIATPQGNGGIGIIRISGIDALAIAEKLTKKQLKPRYATFCNVYNDNEIIDHGIVIFFKAPLSYTGEDVVEIQAHGNPFILNLIIKAALNCGARMAKAGEFTERAFLNNKLDLAQAEAVADIINASSEIAAKSAAKSLQGDFSKEINNLLEKLIYLRMYVEASIDFPEEEINFLEDQKIHSSLEEIYKVILAVKNSCKQGVILAEGITLILVGKPNAGKSSLLNALAGKESAIVTSIAGTTRDIVKEHIQINGVPMHIIDTAGLRNSDDIIESEGIKRAIKKIQEADQVLFVTDDYTNSQVKFSDIKEIIPEFYDQIPKDIDITYVHNKIDLLKEVPHNHANHIYISAENNIGIDKLKEHILNKVGYTNQNESIYTARERHVTAINNAFEHIKLAREQLELGNGELLAEELLIVQEYLNSITGEFSSDDLLGEIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_THEMA
Sequence: MEARYVDLDKLRNIGIMAHIDAGKTTTTERILYYTGRKHFIGDVDEGNTTTDWMPQEKERGITIQSAATTCFWKGYRINIIDTPGHVDFTAEVERALRVLDGAIAVFDATAGVEPQSETVWRQADKYNVPRIAFMNKMDKVGADFYMAVETLVTKLRANPIPVQMPIGSEKDFQGVIDLIKMKAIYWVSEDGSVYEERDIPEELREEAEMRREEMLEKIAELDEEILEKYLEGEEISEEEIKRVLRKATIENKAVPVLCGAAKANKGIQPLLDAVIDYLPSPLDLPPVKGWRVSDGEVVYRKPDENEPFTALVFKVQVDPYIGKLVYFRVYSGRLEKGSYVYNSTKGQRERISRIVFMHADKREEVDYVRPGDIAAGVGLKVSQTGDTLCDEKEPIILEKIDFPEPVISLAVEPVTKADEEKLVKALLALSEEDPTLQVRVDKETGETIISGMGELHLEIVVDRLKREFGVNVRVGQPQVAYRETIKKSAEAEGKYIRQTGGRGQYGHVILRIEPIPEEEGKNFEFIDKTVGGVIPKEFMPAIEAGIKEAMMAGPLAGYPVVRVRAIVLDGSYHEVDSSEMAFKIAASMAFKEAMKKAQPVLLEPIMKLEITTPEEYMGNIISDLNSRRAKVESLETRGHLKVIVAKVPLSETFGYATVLRSLSQGRASYIMQFSHYQEVPEKIAEKIIKVV
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GACL_DICDI
Sequence: MDIELFLSNYNIANGTSSTTANNSKFQPKIKVKLVVESGSSTYEKSLESTNDQLKPLIIKLNNKIKKYEESLNKKNFVTPNKQSSSSMNLLQKSSTVNLSSPSLSQIGLTHHASLKNLQITTSPDIQQPPSVPSNPIVFGISLDTLIAKEKSMELRIPTFVSNILNTLFLHSLGVEGLFRISGSQMEIQNRRGIVNLGDYSTSRDDNPHVLTVLLKQFLRDLPEPICTNALYDLFLAASDQINFQQCKENGFEVLKKLINSNLPVNNRNLLQHLIHFLRFVAMNQTVNLMGPSNLSRVFGPNLFWKKETGPLDIQILQSTSEKVNFITEQMILHYDTLFEEPLQTTSPAVLSNTPINSNPASIPTFNFGGKKLVIHSKLLGHNKSIQWMTLCGSSNSNGNSELSGSRVWSLDSHGMARIWDSQNQQFIKEVEVVDQSKGGGGAVYQMISTTVNNTVWTATSQKLAIWDIDGGLIGEIPGESYSLCESQNKEIWVGGPQVLNIYSLDGIPSIAPSNCTSDDNNSNGAGGGELLKPIGTNLFMKGIIILAMCKVGQNRIWGCSSEKTLYVWDTKTKETIHQCEIQEKRPKRMACIEIDDTEYIWIGGDEGSIQIFNSKTFKLEHKILNQGWDKIFHIASINREIWIGFWDTTVRVFPGDPKNKEILIDYKGYHSDVVSSIIEVPNLKGGDPFVWFGSYDKSISIVSIKEDTAKSWNFTNIKKNFTRPIRQGFSSRG
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacL, GTPase activating factor for raC protein L.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_BACCZ
Sequence: MATEKTYPMTQEGKQKLENELEDLKTVKRKEVVERIKIARSFGDLSENSEYDAAKDEQAFVEGRITQLENMIRNAVIITDNGEESTVVTLGKTVTFKELPNGDEEAYTIVGSAEADPFEGRISNDSPIAKSLLGKQIGEKVAIQTPGGEMQVEIISVK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MCRS1_MOUSE
Sequence: MDKDSQGLLDSSLMASGTASRSEDEESLAGQKRASSQALGTIPKRRSSSRFIKRKKFDDELVESSLAKSSTRVKGAGGVESGRCSGSEPSSSEKKKVSKAPSTPVPPSPAPTPGLTKRVKKSKQPLQVTKDLGRWKPADDLLLINAVLQTNDLTSVHLGVKFSCRFTLREVQERWYALLYDPVISKLACQAMRQLHPEAIAAIQSKALFSKAEEQLLSKVGSSSQPTLETFQDLLHTHPDAFYLARTAKALQAHWQLMKQYYLLEDQTVQPLPKGDQVLNFSDAEDLIDDSKLKDMRDEVLEHELTVADRRQKREIRQLEQELHKWQVLVDSITGMGSPDFDNQTLAVLRGRMVRYLMRSREITLGRATKDNQIDVDLSLEGPAWKISRKQGVIKLKNNGDFFIANEGRRPIYIDGRPVLCGSKWRLSNNSVVEIASLRFVFLINQDLIALIRAEAAKITPQ
What is the function of this protein?
Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus.  As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues.  Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.  May also be an inhibitor of TERT telomerase activity.  Binds to G-quadruplex structures in mRNA.  Binds to RNA homomer poly(G) and poly(U).
What are the official names of this protein?
Microspherule protein 1, 58 kDa microspherule protein.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Cytoplasm. Note=In microspherules in the nucleolus.
Protein: EDNRB_MOUSE
Sequence: MQSPASRCGRALVALLLACGFLGVWGEKRGFPPAQATLSLLGTKEVMTPPTKTSWTRGSNSSLMRSSAPAEVTKGGRGAGVPPRSFPPPCQRNIEISKTFKYINTIVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINTYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDMITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAVFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPHRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
What is the function of this protein?
Non-specific receptor for endothelin 1, 2, and 3.  Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  Essential component in the normal development of two neuronal crest-derived cell lineages.
What are the official names of this protein?
Endothelin receptor type B, ET-B, ET-BR, Endothelin receptor non-selective type.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=internalized after activation by endothelins.
Protein: PTH_CLOTE
Sequence: MFLLVGLGNPGKEYEKTRHNIGFEAVDKISYEYNIPIKRERFKGVFGDGRISNEKVILLKPTTYMNLSGESLREIIEYYNIPITNVIVIYDDVDLEVGRLRIRTKGSAGGHNGIKSIIYNLNSEDFIRLRIGVGKPQRDMVSHVLGKFAKEDEKNIEEVLKIIPELAYTIINQGPQEAMNKYNNFRAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP5G_STAAM
Sequence: MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLFVAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVVPDKNATSEDSEEA
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: LEPA_BACFR
Sequence: MDKIRNFCIIAHIDHGKSTLADRLLEFTNTIQVTEGQMLDDMDLEKERGITIKSHAIQMEYTYKGEKYILNLIDTPGHVDFSYEVSRSIAACEGALLIVDASQGVQAQTISNLYMAIEHDLEIIPIINKCDMASAMPEEVEDEIVELLGCKRDEIIRASGKTGMGVEEILAAVIERIPHPQGDESAPLQALIFDSVFNSFRGIIAYFKITNGVIRAGDKVKFFNTGKEYVADEIGVLKMEMVPRKELRTGDVGYIISGIKTSKEVKVGDTITHVARPCDKAIAGFEEVKPMVFAGVYPIEAEEFEDLRASLEKLQLNDASLTFQPESSLALGFGFRCGFLGLLHMEIVQERLDREFDMNVITTVPNVSYHIYDKQGNMTEVHNPGGMPDPTMIDHIEEPYIKASIITTTDYIGPIMTLCLGKRGELLKQEYISGNRVELFYNMPLGEIVIDFYDRLKSISKGYASFDYHPDGFRPSKLVKLDILLNGESVDALSTLTHFDNAYDMGRRMCEKLKELIPRQQFEIAIQAAIGAKIIARETIKAVRKDVTAKCYGGDISRKRKLLEKQKKGKKRMKQIGNVEVPQKAFLAVLKLD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HUTI_AGRFC
Sequence: MPGNNSAKGTATGNATALWRNAQLATLNPAMDGIGAVENAVIAVRNGRIAFAGPESDLPDDLSTADETTDCGGRWITPALIDCHTHLVFGGNRAMEFEMRLNGATYEEIAKAGGGIVSSVRDTRALSDEVLVAQALPRLDTLLSEGVSTIEIKSGYGLDIETELKMLRVARRLETLRPVRIVTSYLAAHATPADYKGRNADYITDVVLPGLEKAHAEGLADAVDGFCEGIAFSVKEIDRVFAAAQQRGLPVKLHAEQLSNLGGAELAASYNALSADHLEYLDETGAKALAKAGTVAVLLPGAFYALREKQLPPVQALRDAGAEIALATDCNPGTSPLTSLLLTMNMGATLFRMTVEECLTATTRNAAKALGLLAETGTLEAGKSADFAIWDIERPAELVYRIGFNPLHARIFKGQKVSP
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propanoate hydrolase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KVD33_HUMAN
Sequence: MDMRVPAQLLGLLLLWLSGARCDIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQYDNLP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 1D-33, Ig kappa chain V-I region AG, Ig kappa chain V-I region Bi, Ig kappa chain V-I region Lay, Ig kappa chain V-I region Ni, Ig kappa chain V-I region Rei, Ig kappa chain V-I region Roy, Ig kappa chain V-I region Scw, Ig kappa chain V-I region WAT.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: TRMB_STRA1
Sequence: MRVRKRKGAEEHLENNPHYVISNPEEAKGRWHEIFGNNNPIHIEVGSGKGAFITGMAEQNPDINYIGIDIQLSVLSYALDKVLDSGAKNIKLLLVDGSSLSNYFDTGEVDLMYLNFSDPWPKKKHEKRRLTYKTFLDTYKDILPEQGEIHFKTDNRGLFEYSLASFSQYGMTLKQVWLDLHASDYQQNIMTEYERKFSNKGQVIYRVEARF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RINB_BPPHA
Sequence: MGCLVVVKEILRLLFLLAMYELGKYVTEQVYIMMTANDDVEAPSDFAKLSDQSDLMRAEVSE
What is the function of this protein?
Activates int gene expression, probably by providing stability to rinA.  Int activation requires both rinA and rinB.
What are the official names of this protein?
Transcriptional activator rinB.