PharMolix/UniProtQA huggingface dataset:
Protein: Y9956_DICDI
Sequence: MRVLVHVNNAKQSGDGANNSNGTLINYNSNNKLFLEIHPNQSIWMIKTLLFNLFQIPPARQQLYLKVVDEINPRETSKAYSKLLQSYRLVKDYKIYEGTELQMVALEKEIPSEFLVPPKKTQSNSMEKLPHFTNLSMSSMSNMDEILSGSGGGRIHVLSSKKGEECPALCFAVGKGLYRGISGVIYEIKLYRVDSKGMLIVNTSLNFQIDVIKKDSISVEDRKMAFTYEQRKSDYSLLKLQPIIYGEYSISIKIDDTPICGSPFHCTIIDELNPNLKELAFSNEWIEEVVQLITLMSNKPSTIDKLFSFGIEGLMNLMFYPDPTIQIHIIGIFAKLIEKDKNKERVLKEFGMDFIFKLVSLDNWSNFMELRKLVASSLCILSCYKPFLNRFFKEVGIDVISLIARSDFIDCPRSCAIFLSRVSEISFELNEYLISDSIKETLIYLLSIQDNITVNCTLKTISNLSSSFDLKKESNIKLLSNLLEYCKEFQEISKKVLIFKSFSNFCVNESLCTFLISNGILDLITPTHDKSGYFGIPMFCQWESNTINYIISNNNEINLKQYGYEFNQIFKEETDYVFFLSLTISNMLVSTTSLKIHDHFSRGNGLNLLKQFIICHECSVRSEAFRSFMIISNSPNDQCKKHLIQSGIIPYLVSSLFDSLSVETPFIVNTLANLCKYDPTCVENMGVDDIDKFIELLHRDSTSSLSKSISYILSHLIRHDKYKQRIVNGGGKLFLQYLIEFVRQGEISVLKYISQSDLELTKEIGRGVSGVVKRGKWKGYEIAVKQFNEEELGFSEREFHSEATIMSVLRHDNIVHCVGGSAQPGKMYLVCDYYSRGSLYSVITANICPLSNARIVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQDWNIRISDFGLSRVVDNRMTKTVGTPCYMAVEVLKGLTDYSQQADVYSFAFVLWECISRQIPYKDFAQIQWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYLENLRLKMQDQGIYQILTGGSSVGIGGVGVVGVGSGGNSDEHESNIDIDTVSGSNNNESSTAVSLNENKINIDMSMHPTEELKNLVEVSKDDNPTNSDYDIRSSSTSSSPSTLSAPQSPVGSTSPMGSTSTSPISNNNNRPTHDHQQPHQVKWERIVPDKPNPNLKSKRLSAFRNKAVPISITDNNNNNNSANNNNNNNSMKNNSNASRNTFSSVSSPSSSADLSSGIESSNNRDDSFLSSGSSLSEQHRSVSNSVSNSVGGFSLPPPPLAPSFYASMINEKISSSTPTDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNSINNNNNNGIAINYTNSINNNKNSNNNTSNTKYPISKCKSNPSFEALKSKFDKD
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0268876.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Protein: Y1589_ERWT9
Sequence: MDLNNRLSEDETLEQAYDIFLELAVDNLDPADVILFNLQFEERGGAELHDPAEDWAEHVDFDLNPDFFAEVLIGLGEADGEPITDVFARVLICREKDHKLCHILWKE
What are the official names of this protein?
UPF0263 protein ETA_15890.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: AR2BP_CHICK
Sequence: METSEEENFGVAVSSPSDAEFDAVVGYLEDIIMDDDFQSIQRTFMEKHYQEFDDSEENKLIYTSIFNEYISLIEKYIEEKLLDRIPGFNMTAFTMSLQQHKDEMAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRSLDLSGGLVVTSLNKSSVSSS
What is the function of this protein?
Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
What are the official names of this protein?
ADP-ribosylation factor-like protein 2-binding protein, ARF-like 2-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ARL2BP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body. Note=Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity).
Protein: ATP23_PICST
Sequence: MSAVPNAVIPNPDNLSVSAPEKLSGFEWWRRSLQYRTGMGLDPQEKAQFEFDYQHKYLPQQCNSCIEFRDWMLTYSPSVTFMMDHIKKLSPNKEQILNKSNIICDVCDDLKGGGFHPQEGILLCANRIQSKWQLEDILTHELVHVYDHLKFQVNLNDLKHHACTEIRASMLSGECRIFNEIKKTGLGDFGKKFQSCIKRRAILSVSANPICKDSEEAEKVVNSVWQSCFNDTRPFERVYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: THIE_PYRHO
Sequence: MNFKEKLKLYIITDRRLKPEIASVKQALEGGATSIQLRIKNAPTREMYEIGKEIRKLTNEYGALFFVDDRIDVALAVNADGVQLGPDDMPIEIAREIAPNLIIGASVYSLEEALEAEMKGADYLGAGSVFPTQTKKDVKVIGIEGLREIVNAVKIPVVAIGGINLENVREVLLTGVDGIAVVSAVMGTEDVKRATEGLRRIIEEVLG
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: HVM03_MOUSE
Sequence: VQLQQSGAELVRAGSSVKMSCKASGYTFTSYGINWVKQRPGQGLEWIGYINPGNGYTKYNEKFKGKTTLTVDKSSSTAYMQLRSLTSEDSAVYFCARSVYYGGSYYFDYWGQGTTLTVSS
What are the official names of this protein?
Ig heavy chain V region 36-65.
Protein: MINC_SHESH
Sequence: MQTPSLELKGSSFTLSVLHINSIDLEKVAKELDSKLAIAPQFFIGAPLVVNLSSISDSSYNLAALKDLLTSRQLVIVGITAAINTLSEQAKTLGLAIIKSGKQAQSQPQLPKTTKLVKQNVRSGQQIYAKNGDLVVIGTVGNGAEVIADGSIHIYGTLRGKAMAGASGDKHAVIIAKTMEAELVSIAGQYWLTDNIQANSTTKSGCIRLDGESLTIESLPL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: OSTCN_NOTEU
Sequence: YLYQTLGFPAPYPDPQENKREVCELNPDCDELADHIGFQEAYRRFYGTA
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium.
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPP2_SORMK
Sequence: MTTTTRMDYETTLKGKYPAKRHAQRVADYIRNKVPGASGVLYLEGRATKLLEDNDEAEPFRQRRYFYYLTGCPLADCHYMYDIDADKSTLFIPPIDPESVIWSGLPVSADEAKQNWDVDEVKYTSDVNATLAHVGSEKPKGASVFAIPNQVSDKITFLEFDNKNFSILKEAIEVTRVVKDEYELAIMAKANEISSDGHKAVMQKVKHVQNERELEAVFLGHCIAKGSRNQAYHSIVASGRAAATLHYVPNNADMAGKLNLLLDAGGEWDCYASDITRTFPINGKFTKESREVYDIVLKMQNDCIAALKEGVLWDDVHLLAHKIAIDGLLQIGILQGDKDEILESRTSVAFFPHGLGHYLGMDTHDTGGNPNYADKDTMFRYLRVRGRLPAGSVITVEPGIYFCNFIIEPFLKDPKHSKYINADVLEKYWDVGGVRIEDNLVITKDGTYNLTTAPKDPEEMEKIIQQS
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase SMAC_04549, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: RS6_MANSM
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGSVKEAGGQIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRYNDAVLRNVIIRTKHAVTEASPMVKAKDERRASAEVENNDFEDAEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: FK112_ARATH
Sequence: MVKWSELPPEILHLISLKIDNPFDLIHFRSVCSFWRSSSLLKFRHMTSLRCPLPLDPGGCGDDCHILSSRVYLLKCPNRDRPQYWMFKLQAKENGEVVLHSLFLRRNSSAYGCLYPSLSIDLLNCQIFELAQEHVACYSEWFELFECISKCEERIGFMGLNREKNEYMILGKLSFNGLAMYRSVDNRWTELEITPDSFFEGIVPFKGKFYAIDRTGKTTVVDPTLEVNTFQRSRPCDKTRKRWLLMTGDKLILVEMCTKSRYDFHIPNIREKKIWFEISELNEERNDWDQVEDMDGRVLFLEHYCTFSCLATEIPGFRANSIIFMDLWGGSNSYELESILVYEFNEKGVRSLRDKLEYIELFPFPPGWVISNG
What are the official names of this protein?
Putative F-box/kelch-repeat protein At5g24040.
Protein: TRMA_YERP3
Sequence: MTPNILPIESYDHQLAEKSARLKAMMLPFQAPEPEIFRSPADHYRMRAEFRVWHDEDDLYHIMFDQQTKQRIRVEQFPVASRLINRLMDALMTAIRAEPLLRRKLFQIDYLSTLSGKLIASLLYHRQLDEEWQQKALELRDQLRAQGFDLQLIGRAAKTKIMLDHDYIDEVLPVAGREMIYRQVENSFTQPNAAVNIHMLEWALDVTQGATGDLLELYCGNGNFSLALARNFERVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMQGVREFNRLKGIDLGSYNCETIFVDPPRSGLDHETVKLVQAYPRILYISCNPETLCANLEQLQHTHKISRLALFDQFPYTHHMECGVLLEKRH
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: DAPA_METAC
Sequence: MFEGAMPALITPFTKDDRIDREGLRRNIAFVEEGGVSGIVPCGTTGESATLSALEHEEVIDIAVECAKVPVVAGTGSNNTGEALQFTKHAADAGVDGVLLISPYYNKPNPAGLLAHFKKIAEAVDIPMILYNVPSRTGQDMPVDVITKLAKVENIVGIKEASGSVGKVSQILEQTIDDDFVVLSGEDGLTLPIISVGGSGVISVAANIVPDKMSGMVSAALKGDYETARKIHFEIAPLIRALFLETNPIPAKKAAELIGLASGHLRLPLAPMSDANQLKLVTELKKLGVMK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O16H_CONEA
Sequence: THSGGACNSHDQCCNAFCSTATRTCV
What are the official names of this protein?
Conotoxin Eb6.17.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SPTF3_CAEEL
Sequence: MSKSGQQQQPHQQMQQQQQQQGKMMVVHHQRTTTPDGSQVYLLQPSQSHPQQRQVQFIPIQVAQGEKKPQTVMMNQMMGQQQQQQPSSSNQQSQQQVQQQQQQVHQVQQVQQHQMQQQNQTVQQQHLMMETIDQVGSGIIGNSNGNNQQQQQQQQQQQQRRDPIPIAPAGMVSGQRMQQQQQQPQQQQQHNNNNTGASTSNGGVNAAPVMPVMGGQQRITLGNLHFQQDPNDPQKWIITNEGPPVAGPSAPARKPNQIQHRQMIPQMNEDGMMNMGNDYGDINGQGLGEAPKRCACTCPNCLQQNNRQGDGKSRIHICHLCNKTYGKTSHLRAHLRGHAGNKPFACDWQHCNKKFTRSDELQRHRRTHTGEKRFACNHCGKKFMRSDHLTKHERTHQSNRINNINQQTLRLS
What is the function of this protein?
Transcription factor (PubMed:21884786, PubMed:23851392).  Binds to GC-rich DNA motifs, such as 5'-GGGCGGGG-3' (PubMed:21884786, PubMed:23851392).  Involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell, by transcriptionally activating target genes, such as cell death activator egl-1 and leucine zipper kinase pig-1, in caspase-dependent and -independent apoptotic pathways (PubMed:23851392).  Plays a role in the regulation of apoptosis, cell lineage, cell differentiation, embryonic morphogenesis, vulval development, and oocyte production (PubMed:21884786, PubMed:23851392, PubMed:26434722).
What are the official names of this protein?
Specificity protein transcription factor 3.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TX219_APOSC
Sequence: EIPQNLGSDIPHDIIKLPNGQWCKTPGALCSSRSECCKAKHSDSVTYSSGCSRQWSDQQGLFINQCRTCNVESSMC
What is the function of this protein?
Neurotoxin with probable ion channel impairing activity.  In vivo, is both paralytic and lethal, when injected into lepidopteran larvae.
What are the official names of this protein?
U1-cyrtautoxin-As1d, U1-CUTX-As1d, Aptotoxin IX, Aptotoxin-9, Paralytic peptide IX, PP IX.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RTC5_FUSV7
Sequence: MGQNLSDEQPQRRSHEELTHELAERFRSKCFTSLEFYSLKDVFKSLADQQDSIRYMKEDTIARYLEIPDILGASPVIFQMVSYLGAFPFLQDAPVVLELPRMIMVIVIMTERYRTVLARGSADRTKLLFRSLAVFDRKPSESDALIPDAAQLDEPNGKDEKVQENSHVAGFAVDQAGDEVDDDDDEDDDLVLTAFELLDVKEAVDQGHAPKFHSATIPTDNFRKLLMLLLLAAPLDPQESLSLYSPHVVGEQLEGLRATAECILASFVNAETSTGIKYSHFKSIIPVICPNLFRGFNGLFEHFLFSKNLDFSKHQNDIPITKVAQPLLTDSGEILNHNTLCQISLFLPGSDLFRRVRLLYSGNDAGFSMGSFQTKVFNWQAPTLLLVSGTRLSDIPEGGQEVAFAASLPTKRFPHGSKSDQLTFGVYVREPWKHTHRECFGDADTVLFQLEPIHDVFPASTINKDYVTFTKAPAHHPMLSFGCPHPHPSQAHRKADMLHLGPVSLTLDDSFEFAVFNHDFTSRGGAFRSSSVRKFDFQERFQIESLEVWGCGGDAEARAQAERWAWEEREAEARRKINLGTGDIEADRALLEMAGLIGGARSGGSMG
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT1B3_HUMAN
Sequence: MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA
What is the function of this protein?
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.  The exact function of the beta-3 subunit is not known.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-3, Sodium/potassium-dependent ATPase subunit beta-3, ATPB-3.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type II membrane protein. Basolateral cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: TUSB_SALPK
Sequence: MLHTLPHCASGVDFPALLRLLKEGDALLLLQDGVTVAIEGNRFLESLRDAPITVYALKEDIDARGLGGQISDSVVRVDYTEFVRLTVKYANQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_CALS8
Sequence: MKGKFIVFEGNDGSGKSTQILKVEKYLKEKGYKVVTTREPGGTEVGFRIRKLLLDPAYKMDGLTEALLLAADRNEHVKNVLIPALEDGYVVVCDRYILSSIVYQGIVRGVGVENIIKLNSIFEEKIKPDLYIILTLSPEIALQRLKMAGKNDKLDTENFDFHRKVYNGFKEVSKMFKKCVNIEAEGTVEDVFEKVRKVIDDLLKKR
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: MIAB_ECOLU
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENDLGVGYYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_BURMA
Sequence: MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIKTPTADLPTRLGTIYDGVSTLIREHTPDQAAIEKVFVNVNPQSTLLLGQARGAAICGLVSGGLPVAEYTALQLKQAVVGYGRATKEQMQEMVARLLSLSGRPGTDAADALGMAICHAHGGNTLNTLGGIAPALAKKGLRVRRGRLVG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: COBQ_METBF
Sequence: MEKKSVLILGTASHVGKSSVVTAICRILSREYRVAPFKAQNMSLNSWITKDGKEIGIAQAIQAKAAGTEPTADMNPVLLKPKGDCVSQIILLGEPYADRSAGKYYESIAEMNEVLEGALKRLCNEHDIIVMEGAGGAAEINLYERDIVNIGTARLTQAPIILVGDIERGGVFASLYGTVALLPEDVRKNVKGFIINKFRGDLEILKPGLKQLEEKTGIPVLGVLPYFKLNIPSEDSVSLEDKEAEKNEKEIEIAVIRLPRISNFTDFEPLERSAKIRYVELDEDLGTPDAIMIPGTKNTVNDLLDLKASGMAEKIQAFKGKIPIFGICGGYQMLGKTIYDSGVENGVEAEFEGLGLLDIGTKFGEYKKRTIQVTKKVSAYGPILAPIDGEEIKGYEIHMGITDSCRNIFGNDGAIDKAGLVIGTYLHGLFDNKNIRDALMQYLYEKKGLEYIPENSMTESDAYEELANVVEQNLDMEKFYEIIGI
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Probable cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RBSA_YERPN
Sequence: MNKVPLLEMRNITKSFGKFQALKGVDLTVFSGEIHALMGENGAGKSTLMKILAGAYTTTSGEILIEGRPWSIKGPKDALNAGISLIYQEMQLAPNLTVAENIFLGSELSRGGLVQRKEMVMQTQAVIDRLGAQFKASDLVMGLTIAEQQQVEIARALHRNSRILVMDEPTAALSTRETHRLFELILRLRDEGMAIIYISHRMAEVYELSDRVSVLRDGQYVGSLMRANLNANELVRMMVGRPLSDLFNKERDIPLGHLRLKVHHLTDGAKVQAVSLQVRSGEIVGLAGLVGAGRSELAQLIFGVRKATGGTIEIDGVPLVIHSPREAIRHGIGFLTENRKEQGLFLELAAQDNITMATLERDACYGLLDRKKARAISDDAINRLNIRVPHAQVRAGGLSGGNQQKLLISRWVAISPRILILDEPTRGVDVGAKSEIYRIMSQMAREGVAILMISSELPEVVGMSDRVYVMHEGRIAGELHHPDITQENIMTLATGVTEDHKKEVYHD
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KCY_SALA4
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDLASEDALVPLASHLDVRFVSTDGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFREAPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQENGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTRLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y537_PSET1
Sequence: MLRWTITFLVIALIAAVLGFGGIAGAAAGIAKIIFFIFLILLVISLVSGALRGKKP
What are the official names of this protein?
UPF0391 membrane protein PSHAa0537.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZCH10_RAT
Sequence: MATPMHRLIARRQAEANKQHVRCQKCLEFGHWTYECKGKRKYLHRPSRTAELKKALKEKENRLLQQSMGETNTERKTKKKRRPKSVTSTSSSDSSASESSSESETSASSSSEDSDADGSLSSSSSSSAYSSSSSSSSSSSSSSSDSDSSSSSSSSSSSESSSDDEPPKKRKKK
What are the official names of this protein?
Zinc finger CCHC domain-containing protein 10.
Protein: CYAY_BURA4
Sequence: MSDTEYLARAEAVLASVERTVDAANDGDHDIDLERNGSVLTLTFENGSKIIINLQPPMKELWIAAKAGGFHYRFVDGEWRDTRTGTEFFSALTDYATQQAGLPITFRA
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: TRUB_PARD8
Sequence: MDFIAGEILYFNKPLTWTSFDLVNKFRYKLSRKLKVKKIKVGHAGTLDPLATGVMIVCTGRATKRIDEFQYQTKEYIATLKLGETTPSFDLEKEIDAVYPTEHITRELVEEVLKTFVGTIQQIPPVFSACKVEGKRAYELARKGEEVELKSKTLVIDELELLECDLPVIKIRVVCSKGTYIRALARDIGKALGSGAHLIGLERTRIGEVTLDMCMSPEEIDDFLEQNVVKIEEEK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: Y6014_CUPTR
Sequence: MPSTPESDPTQPGDRPARPALRPLTPVEGRVLGVLVEKQHTVPDTYPLSLNALASGCNQKTARAPVMNVSEAEILEAIDGLKSLSLVFEGSSSRVPRFEHNMQRALGIPSQSVALLALLLLRGPQTAAELRLNTARLHSFADISSVEAFLDELASQTPPRVVRLPRAPGARENRWMHLLSGEAGAAVAAEESARNTDGDAAPSAELEQLRTEQQALAEKVARLQGLVEHMAAQLGISADEFLG
What are the official names of this protein?
UPF0502 protein RALTA_B0914.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: HXD3_HUMAN
Sequence: MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGGNFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQGRLPEAPKLTHL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D3, Homeobox protein Hox-4A.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROB_DEHM1
Sequence: MKSIGLNLSGREYKILIGSDLLAETADLLKQAIPCDRVVVITNIDINRLYGKKLKKHLESKGIGSLFLELPEGEIHKSLDMASHIYPQLINHFAERNTPILALGGGVIGDLSGFVAATYQRGVPLVHLPTSLLSQVDSSIGGKVAVNHGGIKNIVGSFYQPRLVISDISCLKTLPEKEFACGMAEIIKSAAIGSSELFKQLETNTPAIKDRSPEIMEDIISQTAAIKAGIVCQDETDRGIRNILNFGHTLGHALESTSSFSQSHGAAVAIGMCFASRLSVKLGLCENETVLRLEKLIADFGLPTRPQDIDPEKIIDAMHHDKKVSDGRIRFILLKRPGEPLIAENILRADVISILEEMK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.