PharMolix/UniProtQA huggingface dataset:
Protein: RS13_AQUAE
Sequence: MARIAGVDLPNNKRLEVALTYIYGIGWSRAREICEKTGIPCTKRVGELTPDELNTLRKFIDENYKVEGDLRREVQLNIKKLKDMGCYRGIRHARGLPVRGQQTRTNARTRKGKRKTVGGTKKAKAK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NIFA_RHILT
Sequence: MPKSTVRPGAEIVGESAALKEVLEIAQIVARSNSPVLLRGESGTGKEFFAKLIHDSSSRHEKPFVKLNCAALSAGVLESELFGHEKGAFTGATSQKEGRFELAHGGTLLLDEIGEISAEFQAKLLRVLQEGELERVGGTRTLKVNVRLVCATNKDLETAVAAGEFRADLYYRINVVPITLPPLRQRDGDIPRLAQKFLQRFNRENGRSLSFAPATLDILSKCEFPGNIRELQNCTQRTATLARSDVIVPQDLACEQGRCYSPILKKAVAEQVGKGAIHGLARGETESMGQPCDVGVFAAETVMGQSGLIGRERLEQAMATAGWVQAKAARLLGRTPRQVGYSLRRHGIERKVF
What is the function of this protein?
Required for activation of most nif operons, which are directly involved in nitrogen fixation.
What are the official names of this protein?
Nif-specific regulatory protein.
Protein: SELD_HAEIN
Sequence: MEEKIRLTQYSHGAGUGCKISPKVLGTILHSELEKFYDPNLIVGNETADDAAVYDLGNGTAIISTTDFFMPIVDDPFDFGRIAATNAISDIFAMGGKPIMGIAILGFPTNVLPAEVAQKIVDGGRFACHQAGIALAGGHSIDSPEPIFGLAVTGVIDTEKVKRNASAKSGCKLYMTKPLGIGILTTAEKKGKLKPEHQGLATAAMCQMNSIGSQFSQVDGVTAMTDVTGFGLLGHLIEICEGSNLSAVVFSDKIKTLDGVKDYIAQGCVPGGTGRNFDSYGHKVGILTEEQKAILCDPQTSGGLLVAVELNSVQTVIDIAKDAGIDLYEVGKLKPKSESDIVVEVK
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: YPV5B_METTF
Sequence: MKAWNLDVQNATARVQLPEGLVVQDYYMSQGYYDLETGTWEIGDIPAYEERSLTFICLLNRTGSVTVNANVTADGDDNSANNNAELTFKVFGISDLEVNVTGNKETARIGDTVRITVKLKNRGPHDANNIKIGNFLSGGLVVQNFSYDAGYFDDITREWIFETLAAGEEATLTLDCLVNRTGELSDYVSVREVDEGDVNVYNNMAHASVAVKGTDLDLDLSVSKLRAYQGDVVNVVCRVRNNGPETAQNARVNLQLPGNLQVQHVQLDRGTYSNGVWVIGDLADNETALLNITARVMSAGNFTLNATAVSPAIDDSNPVNNDDTARISVAIPKKTLKVRIKNNSAVTIRVLLYVTVNDHGKITRKTYNFYLKKGLSRDLSLGYFQLGTTALFKQYTYNTNYRSRTVSYENTYNATSVITQRVNVSGVKGRQKAPVVRIATLLLDENGTSLQ
What are the official names of this protein?
Uncharacterized protein ORF5B.
What is the protein family that this protein belongs to?
To ORF5 in pFZ1.
Protein: CARA_STAAC
Sequence: MQSKRYLVLEDGSFYEGYRLGSDNLTVGEIVFNTAMTGYQETISDPSYTGQIITFTYPLIGNYGINRDDFESLVPTLNGIVVKEASAHPSNFRQQKTLHDVLELHQIPGIAGVDTRSITRKIRQHGVLKAGFTDRKEDIDQLVKHLQQVELPKNEVEIVSTKTPYVSTGKDLSVVLVDFGKKQNIVRELNVRGCNVTVVPYTTTAEEILAMAPDGVMLSNGPGNPEVVECAIPMIQGILGKIPFFGICLGHQLFALSQGASSFKMKFGHRGANHPVKNLETGKVDITSQNHGYAIDIDSLKSTDLEVTHLALNDGTVEGLKHKTLPAFSVQYHPEANPGPSDSNYLFDDFVAMMTNFKEKERHINA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: GSA_ECOLI
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKYTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEGLLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL
What is the function of this protein?
Aminomutase that catalyzes the transfer of the amine group on carbon 2 of glutamate 1-semialdehyde to the adjacent carbon 1 to form 5-aminolevulinate.
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_ROSS1
Sequence: MIPLIAIVGPTAVGKTALSIRLAQQFNGEIVSVDSRQVYRGMDIGTAKPTPAERAAVPHHLIDIVDPDEAFSLAVYQDLATAAIADIAARGRLPFLVGGTGQYLAAVLQGWQLPRVAPRPDIRAALERQAAELGAAALYARLAEIDPAAAASIPPNNIRRIIRALEVYEATGKPISEQRSVQPPPYHTVTIWLTLPTPALYARIDARVEAMIAAGLLDEVHRLLERGYHWDLPSMSGLGYREFRPYFEGRITLDEAIARLKYDTHAFARRQPAWFRRLPNVLTLPADASDLQQQAATIVRQWIDA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: NAT12_ARATH
Sequence: MSSSDPKPGPKPGPWPPTPESAAMPPSSWAKKTGFRPKFSGETTATDSSSGQLSLPVRAKQQETQPDLEAGQTRLRPPPPVSAAVTNGETDKDKKEKPPPPPPGSVAVPVKDQPVKRRRDSDGVVGRSNGPDGANGSGDPVRRPGRIEETVEVLPQSMDDDLVARNLHMKYGLRDTPGLVPIGFYGLQHYLSMLGSLILVPLVIVPAMGGSHEEVANVVSTVLFVSGITTLLHTSFGSRLPLIQGPSFVFLAPALAIINSPEFQGLNGNNNFKHIMRELQGAIIIGSAFQAVLGYSGLMSLILRLVNPVVVAPTVAAVGLSFYSYGFPLVGKCLEIGVVQILLVIIFALYLRKISVLSHRIFLIYAVPLSLAITWAAAFLLTETGAYTYKGCDPNVPVSNVVSTHCRKYMTRMKYCRVDTSHALSSAPWFRFPYPLQWGVPLFNWKMAFVMCVVSVIASVDSVGSYHASSLLVASRPPTRGVVSRAIGLEGFTSVLAGLWGTGTGSTTLTENVHTIAVTKMGSRRVVELGACVLVIFSLVGKVGGFLASIPQVMVASLLCFMWAMFTALGLSNLRYSEAGSSRNIIIVGLSLFFSLSVPAYFQQYGISPNSNLSVPSYYQPYIVSSHGPFKSQYKGMNYVMNTLLSMSMVIAFIMAVILDNTVPGSKQERGVYVWSDSETATREPALAKDYELPFRVGRFFRWVKWVGI
What are the official names of this protein?
Nucleobase-ascorbate transporter 12, AtNAT12.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPB_ROSDO
Sequence: MANAVGKITQVIGAVVDVQFADHLPEILNALETNNNGNRLVLEVAQHLGENTVRAIAMDATEGLVRGQTVTDTDGPISIPVGNATLGRIMNVVGEPIDEKGPVATDETRSIHQEAPAFAEQSTSSEVLETGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGFSVFAGVGERTREGNDLYHEMIESSVIVPDNLTESKVALVYGQMNEPPGARMRVALTGLTLAEQFRDQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAMQERITSTKAGSITSVQAVYVPADDLTDPAPATSFAHLDATTVLSRAISELGIYPAVDPLDSTSRLMDPQVLGEEHYNVARDVQGILQRYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFDVAKVFTGSDGKQVPLAETIESFKAVVAGEYDHLPEGAFYMVGGIEEVKAKAEQMAADAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ISPH_NOSP7
Sequence: MDTKAFKRSLQHSENYNRKGFGHQAEVATQLQSEYQSNLIQEIRDRNYILQRGDVTIRLAQAFGFCWGVERAVAMAYETRQHFPTEHIWITNEIIHNPSVNQRMQEMEVEFIPIEGKNKDFSVVGTGDVVILPAFGASVQEMQILHDKGCKIVDTTCPWVSKVWNTVEKHKKIDYTSIIHGKYKHEETVATSSFAGKYLIVLNLQEAQYVADYIINGGNREEFLTKFAKACSAGFDPDRDLERVGIANQTTMLKDETEQIGKLFERTMLQKYSPIELNQHFQSFNTICDATQERQDAMLELVEHNLNLMVVIGGFNSSNTTQLQQIAFERRIPSYHIDTVERIKSGDSIEHRQLNGQLITTENWLPDGEIVVGITSGASTPDKVVEDVIEKIFAVKATAALV
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MIP_MOUSE
Sequence: MWELRSASFWRAIFAEFFATLFYVFFGLGASLRWAPGPLHVLQVALAFGLALATLVQTVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYIAAQLLGAVAGAAVLYSVTPPAVRGNLALNTLHAGVSVGQATTVEIFLTLQFVLCIFATYDERRNGRMGSVALAVGFSLTLGHLFGMYYTGAGMNPARSFAPAILTRNFSNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSVSERLSILKGARPSDSNGQPEGTGEPVELKTQAL
What is the function of this protein?
Water channel.  Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased.  May be responsible for regulating the osmolarity of the lens.  Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.  Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity).
What are the official names of this protein?
Lens fiber major intrinsic protein, Aquaporin-0, MIP26, MP26.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: Y287_METJA
Sequence: MRIPPPLSNNKNRNRRYKRSQFEVIFEILHIIKEGEQIKTRIMYAANLDWRNFSKYIDFLISNGFIKKNKEKFELTELGKKLYSSLYELFEIMNSKP
What are the official names of this protein?
Uncharacterized protein MJ0287.
Protein: GANA_ASPFN
Sequence: MLFSYLLATLPLLANAALTYKGADISSVFIEEKAGVAYKNLAGETQALEAILTDNGVNSIRQRVWVKNGDYDLTYNVNLAKRVAATGASIYLDLHYSDDWADPKHQTTPDGWSTDDINTLADQIYQYTLSVCNTFAEEKINVEIVSIGNEITSGLLWPLGKTPNYENIARLLHSGAWGVKDSKLATKPKILIHLDNGWDWDQQKYFYDTALGTGLLTSDDFDMIGVSYYPFYNEKATLASLKTSLTNIQTTYGKEVAVVETNWPVKCSSPEFAFPADLKDIPFSVDGQVTFLQRLADTLTATKASGFFYWEPAWTKNAGLGSSCEDNLLVDYNTNQVRSSVKAFGQV
What is the function of this protein?
Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin.
What are the official names of this protein?
Probable arabinogalactan endo-beta-1,4-galactanase A, Endo-1,4-beta-galactanase A, Galactanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 53 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMD_LACP3
Sequence: MQIDVLSLFPNMFEPLRESMIGKAIERELLNFDVVDYRSYSHDKHHHVDDTPYGGGAGMLLKPEPLFEAMDGVNERHPGPKRVILMDPAGKKFNHQAARALSQEDHLVFICGHYEGYDERIRTLVTDEYSLGDYVLTGGELPAMVMIDAIVRLLPGVLGNDESAHTDSFENGLLEYPQYTRPPEYRGMKVPEVLQNGNHQLIARWRQKESLRRTYLRRPDLLKTITLDQTAQKLLREVKTEEATKAAEARLKNQS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_PROM9
Sequence: MSSSFGKIFRVSTFGESHGGGVGVILDGCPPKLKIDIKLIQNELDRRRPGQSDITTPRNEDDKIEILSGIKEGLTLGTPIAMLVRNKDQRPGDYNNLEQVFRPSHADGTYHLKYGIQAGSGGGRASARETIGRVAAGAVAKQLLKNLCNTEILSWVKRIHDIDSDVNKEKISLNKIDSNIVRCPDEKVSAEMIDRIKDLKRQGDSCGGVIECLVRNVPSGLGMPVFDKLEADLAKALMSLPATKGFEIGSGFSGTYLKGSEHNDSFIKSDDISKLRTTSNNSGGIQGGISNGENIEMKIAFKPTATIGKEQKTVNAEGKEVLMKAKGRHDPCVLPRAVPMVDAMVALVLADHLLLNNAQCGLMKN
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: EFG2_PARXL
Sequence: MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMAGDRAEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFINKMDRTGANFFKVYDQLKLRLKANPVPVVVPIGAEENFTGVVDLLKMKAIIWDEASQGTKFSYEEIPAELVDSCNEWREKMVEAAAESSEDLMNKYLEEGELTEAEIVKGLRDRTIACEIQPMLCGTAFKNKGVQRMLDAVLDFLPSPIDIPPVTGELENGEKGERRAADDEKFSALAFKIMTDPFVGQLIFFRVYSGVVNSGDTVLNATKDKKERLGRILQMHANQREEIKEVRAGDIAAAVGLKDATTGDTLCDPQSPIVLERMIFPEPVISQAVEPKTKPDQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEATVGKPQVAYRETIRGKAEDVDGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFLDEIKGGVIPREYIPAVDKGIQETLKAGVLAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAMRKAQPVILEPMMAVEVETPEDYMGNVMGDLSGRRGIVQGMDDMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYSEAPRNVSEAIINAKSK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPG1_STRSG
Sequence: MEKEKKVKYFLRKSAFGLASVSAAFLVGSTVFAVDSPIEDTPIIRNGGELTNLLGNSETTLALRNEESATADLTAAAVADTVAAAAAENAGAAAWEAAAAADALAKAKADALKEFNKYGVSDYYKNLINNAKTVEGIKDLQAQVVESAKKARISEATDGLSDFLKSQTPAEDTVKSIELAEAKVLANRELDKYGVSDYHKNLINNAKTVEGVKELIDEILAALPKTDTYKLILNGKTLKGETTTEAVDAATAEKVFKQYANDNGVDGEWTYDDATKTFTVTEKPEVIDASELTPAVTTYKLVINGKTLKGETTTKAVDAETAEKAFKQYANDNGVDGVWTYDDATKTFTVTEMVTEVPGDAPTEPEKPEASIPLVPLTPATPIAKDDAKKDDTKKEDAKKPEAKKDDAKKAETLPTTGEGSNPFFTAAALAVMAGAGALAVASKRKED
What is the function of this protein?
Binds to the constant Fc region of IgG with high affinity.
What are the official names of this protein?
Immunoglobulin G-binding protein G, IgG-binding protein G.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: CYNS_ECOLI
Sequence: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: PYRF_CALS8
Sequence: MLNFSDRLIESIKKKNSVLIAGIDTSIENVPDYFIKRFYDREKSEIDNLKTILFEYNRRIIDAVEENVVGVKFQAAFFEQYSYHGFEVLHKLCEYAKNKKLVVIFDGKRNDISSSAKGYSNAYLGETPVFGRKIRFFEFDAITTNPYLGQDGIKPFVEDCERFKKGLFVLVKTSNPSSADFQDLTVEDKYLFEVVAEKVYEWGKNCVGKEGYSDIGAVVGATQKEAAKRIREILPNSFLLVPGIGVQGGKVEDLKYFVDSNNMGIIVNSSRDIIYAYKNYVHSDFEKSSYLASKSIKESINAAIS
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: ACCA_CHLTE
Sequence: MAAKVVLDFEKPLYELEEKLNEMRVYLKSGEVDSMSEGRAGLKREIESLEAKVESLRKTIYKNLTRWQKVQLARHPERPYTLDYIYMMMKDFVELSGDRNFGDDKAIIGGFARLEDESAGFSQSVMVIGHQKGRDTKSNLYRNFGMAQPEGYRKALRLMKLAEKFRKPVITLIDTPGAFPGIEAEERGQAEAIARNLYEMAALKVPVICVIIGEGASGGAIGIGVGDRILMAENAWYSVISPESCSSILWRSWNFKEQAAEALKLTADDLLAQGIIDRIVTEPLGGAHHNPEQMASTLKSILIEELQGLLTKDARTLVDERIAKFSGMGVWEES
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYCA_METTH
Sequence: MFSKILVANRGEIAIRVMRACRELGIKSVAVYSEADKNALFTRYADEAYEIGKPAPSQSYLRIDRILEVAEKAGAEAIHPGYGFLAENPRLGEECEKQGIKLIGPKGSVIEAMGDKITSKKLMKKAGVPVIPGTDQGVSDPDEAARIADSIGYPVIIKASAGGGGIGMRAVYEEDELIRAMESTQSVAASAFGDPTVYIEKYLERPRHIEFQVMADESGNVIHLADRECSIQRRHQKLIEEAPSPIMTPELRERMGSAAVKAAEYIGYENAGTVEFLYSNGDFYFLEMNTRIQVEHPITEVITGVDLVKEQIRVASGEELRFTQKDINIRGHAIECRINAENPLADFAPNPGKITGYRSPGGIGVRVDSGVYMNYEIPPFYDSMISKLIVWGMDRQEAINRMKRALSEYIILGVKTTIPFHKAIMRNEAFRRGELHTHFVDEYRRGIDAEMRKIVKEDQEMVERLQSTFLPSKKVAAISAAIGTYMHSRRG
What is the function of this protein?
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
What are the official names of this protein?
Pyruvate carboxylase subunit A, Pyruvic carboxylase A.
Protein: SYP_CAMJ8
Sequence: MRFTKFYAPSLKEAPKDASLPSHIFLTRAGFIEQIGSGLYNFLPLGKRVLDKIKNIVKEEMDKAGAQEVNLSFITPASLWQESGRYNVFGKELLRFKDRKENEFVLGPTHEEAMLSLVKNKITSYKQLPLHLYQIGLKFRDEARPRFGLLRCREFLMKDGYSFHANEEDLGCEFELMYKTYSQILQRMGLDFRAVEADSGAIGGSGSKEFMVLAKNGEDDILICENCDYAANVEAAKRAKKTCQDERPEANYASKFHTPNIKTIDSLAQFFKINAFYTIKAVVKKAIYENESKLVVFFIRGSDDLQEIKAQNACSALELVDASEEELEKAGLVAGFIGFVGLKDIDFYIDFELENEKQMIMGANEKDYHLIGIDVVNLNKDRFKDLIEVKEGDCCAKCGAKLKQSKGIEVGHIFKLGQKYSKAMNANFLDENGKSQPFYMGCYGIGVSRLLAVAIEASHDEKGCIWNKTLAPFVLEIIVSNLKDEKALEFANKLYEDLTNLGLEVLLDDRNERFGVKMNDFELMGFPYALVIGKGLENNEIELIQREGLVKELIKTDELMEILKKKVL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCN6_MOUSE
Sequence: MAGCRGSVCCCCRWCCCCGERESRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFSVRLFTQLKFGVVQTSVEECSQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEIKCYLNGVKVPGIVRLRTLLCKVFGVLFSVSGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFVVMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVSLVTTVVVFVASMVLGECRQMSSTSQTGNGSFQLQVTSEDVNSTIKAFFCPNDTYNDMATLFFNSQESAILQLFHQDGTFSPVTLALFFILYFLLACWTFGTSVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHLYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMVTLMVAKWTGDLFNKGIYDVHIGLRGVPLLEWETDVEMDKLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEKEFMKGNQLISNNIKFKKSSILTRAGEQRKRGQSMKSYPSSELRNVCDEHVASEEPAEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLVLRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRYPDIHDLDLTLLNPRMIVDVTPYMNPSPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGIITRHNLTNEFLQARLRQHYQTL
What is the function of this protein?
Voltage-gated channel mediating the exchange of chloride ions against protons.  Functions as antiporter and contributes to the acidification of the late endosome lumen.  The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons.  The presence of conserved gating glutamate residues is typical for family members that function as antiporters.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter 6, Chloride channel protein 6, ClC-6, Chloride transport protein 6.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-6/CLCN6 subfamily.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein.
Protein: PYRF_HELPJ
Sequence: MQLCVALDLEKKEDNLSLLQELKGLDLWAKVGLRSFIRDGATFLDEIRKIDGNFKIFLDLKLYDIPYTMANAALECAKLDIDMLTVHLSSAKSALTILMQRLNALKKRPLIMGVSALTSFSEEEFLMVYNAPLKTQAITLSAIGKESGIDGVVCSVFESLAIKEALGKGFLTLTPGIRLDKNDKEDQERVANAKEAKQNLSDFIVVGRPIYQAKEPREVVLELLKDC
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: BTUD_ECODH
Sequence: MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFATPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPPNLAQAYGMNFRRLDIEGHRMLISTI
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NIFN_BRADU
Sequence: MALVTAPTKACVVNPLKMSQPIGGAYAFMGLRGAMPLLHGSQGCTSFGLTLFVRHFKEAIPLQTTAMSEVATVLGGYENLEQAILNISKRAKPKIIGICSTGVTETNGDDVEAYLKLIRSAYPQLTKLPLVYVSTPDFKGAFQDGWEKAVARMVEVLVDRPSANGLRDPSKVNVLPGCHLTPGDLDELRALLEDFGLYPSFLPDLAGSLDGHIPDEFTSTTIGGIDVDEIASMGRAGWTIAIGAQMQRAAEVMQTKTGVPFRVFERLCGLHPNDDFMMFLSEISGRPIPSKYRRQRSQLADAMLDAHFHIGGRKVAIGAEPDLLFDLSGMLHDMGAQVTVAVTTTQSEVIERIRTKEVLIGDLEDLEGFAKEKHCDLLITHSHGRQAAGRLKVPFYRVGFPIFDRLGAGHQVSVGYRGTRNVIFQIANLVIAHRDENDRPTPDRWRTTPGLPQHVGHRRSTGAPERSIA
What is the function of this protein?
This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).
What are the official names of this protein?
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifN.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: STMN1_PIG
Sequence: MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD
What is the function of this protein?
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules.  Prevents assembly and promotes disassembly of microtubules (By similarity).  Its phosphorylation at Ser-16 may be required for axon formation during neurogenesis.  Involved in the control of the learned and innate fear (By similarity).
What are the official names of this protein?
Stathmin.
What is the protein family that this protein belongs to?
Belongs to the stathmin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.