PharMolix/UniProtQA huggingface dataset:
Protein: RS12_SALAI
Sequence: MPTIQQLVRKGRQAKTTKTKTPALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVKLSSQIEVTAYIPGVGHNLQEHSIVLVRGGRVKDLPGVRYKIVRGSLDTQGVRNRKQARSRYGAKKEKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RISB_SHELP
Sequence: MNVVQGNIESKNAKVAIVVSRFNSFVVESLLEGAVDTLKRFGQVADDNITVVRVPGAVELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQIALEFDLPVSFGVLTTDTIEQAIERSGTKAGNKGGEAALGLLEMVNVLQELEQQL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MCFC_DICDI
Sequence: MVLNENDKEFVKKLFDSLDKDNNGKLTREEIKEGFFKLRIPSSEKDIESFLTNVDKDKDGSVSFKEFEDFTIENIKKLKIVFEELDTNKSGTLDIHEIEESIKKLNIPLYSEQELIRLFHRIDKNRDNQIDFNEWRELLVLLPNSNLQLIISFWKDSQILDAGFDNGGFIPPMVEKKEKASSLRNTITYMLAGSVAGFASRTSTAPLERVKIMCQLNHGKPISLISAFKACYKDGGIKGFFRGNLANIIKVSPESAVKFGTYEYVKKLFAENDCELTSAQRFISGSVAGVVSHTTLFPLEVVRLRLSAEIAGTYNGIFDCFKKIAISEKSIRPFYRGLGASITATIPHSGVNMMVYEFLKHKVIKMTGNEFPTAGQLLVCASTSSVCGQLVGYPFHVVKSRLITQGSSVNQEKYTGLFDGLTKIIKKEGPIGLYKGIVPSFMKSIPSHSITFIVYEGFKKAFDVNLKEKKHH
What is the function of this protein?
Calcium-dependent mitochondrial solute carrier.  Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial substrate carrier family protein C.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RAE1_RAT
Sequence: MADNLPSDFDVIVIGTGLPESIIAAACSRSGQRVLHVDSRSYYGGNWASFSFSGLLSWLKEYQENNDVVTENSMWQEQILENEEAIPLSSKDKTIQHVEVFCYASQDLHKDVEEAGALQKNHASVTSAQSAEAAEAAETSCLPTAVEPLSMGSCEIPAEQSQCPGPESSPEVNDAEATGKKENSDAKSSTEEPSENVPKVQDNTETPKKNRITYSQIIKEGRRFNIDLVSQLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGTVEQVPCSRADVFNSKQLTMVEKRMLMKFLTFCVEYEEHPDEYRAYEGTTFSEYLKTQKLTPNLQYFVLHSIAMTSETTSCTVDGLKATKKFLQCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGIYCLRHSVQCLVVDKESRKCKAVIDQFGQRIISKHFIIEDSYLSENTCSRVQYRQISRAVLITDGSVLKTDADQQVSILAVPAEEPGSFGVRVIELCSSTMTCMKGTYLVHLTCMSSKTAREDLERVVQKLFTPYTEIEAENEQVEKPRLLWALYFNMRDSSDISRDCYNDLPSNVYVCSGPDSGLGNDNAVKQAETLFQQICPNEDFCPAPPNPEDIVLDGDSSQQEVPESSVTPETNSETPKESTVLGNPEEPSE
What is the function of this protein?
Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex.  Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction.  The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.  Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.
What are the official names of this protein?
Rab proteins geranylgeranyltransferase component A 1, Choroideremia protein homolog, Rab escort protein 1, REP-1.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: HPRL_HALS3
Sequence: MDRLKQSLLDAPIIEKDGYHYFVHPISDGVPMLEPELLREIVIRIIRKAELDEVDKIVTPAAMGIHISTAVSLMTDIPIVVIRKREYGLPGEVALSQETGYSENEMYINDVHEGDRVLVLDDVLSTGGTLRAITDALEQTGADVADVLAVIKKAGPNELDDTDMDVRTLINVDVADGEVVVVDDQGDH
What is the function of this protein?
May catalyze a purine salvage reaction, the substrate is unknown.
What are the official names of this protein?
HGPRTase-like protein.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
Protein: GLMU_STRMK
Sequence: MTQPLHVIILAAGAGKRMKSVLPKVLQPIAGQPMLAHVIDAARELQPAAIHVVHGHGGEAVRQYFAGQPDLQWAEQAQQLGTGHAVAQAMPQVPDLAQVLVLYGDVPLIRAQTLRDLLAQPGRLAVLVADVDDPTGYGRVLRDAEGKVGAIIEQKDATDDQLRVRTINTGIIAAESTALRRWLSQLSNSNAQGEYYLTDVFAFAAHEYTPAEMALVADAQEAEGANDPWQLSQLERAWQRRAVRALCAQGARVRDPARLDIRGTVTVGSDVLIDVDVVLEGKVVLGDGVTVGPFNRLKDVNLGPGTDVRAHCDLEGVVTEGAAQIGPFARLRPGTVLADGVHVGNFVETKKVTLGVGSKANHLTYLGDAVIGSKVNIGAGTITCNYDGVNKSTTTIGDNAFIGSNSSLVAPVTIGDGATIAAGSVITRNAPDGKLTLARARQETIDGWKRPLKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIROP_MOUSE
Sequence: MKMWRLLLLGVATGRCLHEETQKSVRLLRPPFSQMPTHFRSSILPLPGSHEPRPLRIQTYYSRAPVPGEAWDPEGETRALAAVTETTRRIQGILAVLPVQGPLLLSRDPAQYCHAVWGDPDTPNYQRCSILNPGYKGESCLGAKIPDAHLRGYSLWPEHGLPQLIQPDGPGVQNADFLLYVQVAHTSKCHKEPSVIAYAACCQLDSEDRPLAGTIVYCGQHLRSPTLSHDDIVMATLHELLHALGFSGQLFKMWRDCPSGLSARENCSTRKQVTRRDERGQLLLTTPAVSHSLAKHLGVPGTLQGAPLEEKQGSLSSHWESRLLQGSIMTATFHGAQHTRLDPVTLAAFEDSGWYQVNHSAAEELLWGQGSGPDFGLVSTCRTGSSDFFCTGSGLGCHYLHLDKGSCDSDSTLEGCRIYKPLAKGSECWKEENGLHTRAENPHGEIYHRHSRCFLANLTSQVLSKHTSQPSTAPDLEDPTGCCYLHQCTHKGAYEVQVEGSPWIPCLPGKAVQIPGYDGLLYCPQGRLCLRDEGARAATSQPMSFTTQDLLSQLSLRLTGTPGHSLGKGQREELAEVVLQALVMRAGTSRCYFHSPTITTSLVFTVSMWKSPGCHGPSVAMLHRTLTLTLQMKPLQVHHGEAIFTTDYSKLWTSLDHNPSMTELLLSTGFCLLVLILVGALGTLAYQKRAMLQVAPSTT
What is the function of this protein?
Putative metalloproteinase that plays a role in left-right patterning process.
What are the official names of this protein?
Ciliated left-right organizer metallopeptidase, Leishmanolysin-like peptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M8 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LEPA_RICPU
Sequence: MNHQKYIRNFSIIAHIDHGKSTLADRLIEHCGGLQAREMSQQVLDSMDIEKERGITIKAQTVRLVYKAKDGNTYYLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDSTQGVEAQTLTNVYQAIENDHEIVLVLNKLDLPASEPEQVKQQIEDIIGIDTSEAVLISAKSGIGIDLVLEAIVNKLPPPKESSSDILKALLVDSWYDPYLGVVILVRVIDGYLRKNMRIKMMATNSVYNVENVGYFTPKKHISDVLHAGAIGFFTAAIKQVADCKVGDTITDEKKPCEQALPGFKPNLPVVFCGLYPTDSSEFEHLKDSLAKLRLNDASFEYEMESSSALGVGFRCGFLGLLHLEIIQERLSREFDLDLITTAPSVVYKIHMRDGENLEIHNPADLPDLQKIESMEEPWIKATIMVPDEFLGAVLSLCTEKRGMQLDHSYIANRAKIIYKLPLNEIVYDFYDRLKSCSKGYASFEWQMDVYEPSELVKLGILVNAEVVDALSTIVHRSRAEQRGRALCVRLKDLIPRQQIDIAIQASIGSRIIARETIKALRKDVLSKCYGGDISRKRKLLEKQKAGKKRMRQYGNIEIPQSAFIAALKIGDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HIS4_STRM5
Sequence: MSFIVYPALDIRDGRVVRLRQGDYAQETSYGDDPLPRTQAFAAQGAQWMHLVDLDAARAGGYTLAPLLSSIRAQTTLQVQTGGGVRGRDDVARILDAGAGRVVVGSLAVRRPDEVVGWLEEFGAERITIALDARQDAQGQWQLPVHGWTENADVTLDDLARRYARAGMRHLLCTDIARDGMLAGPNISLYQHLSALLPGVAVQASGGIRDVADVAEARAAGCGGAILGKALLEQRMDLAEALAC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP_SALTI
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDNFAPRAFFSTLTNVNFDSPRIVGYARDAIAMREALKAQCLSVDANAHCDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECAMEIGQMNFKVMSILDAGETTKYGHPTPTQVNVKATEGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGSYDDRIWTRSIVGWPGVSHLEGDDFGPVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLVGGCDGARGERNYFTDFVTSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFFTPDLLAILNEKFGLRSVTTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_PROMS
Sequence: MKKLEDLILTYKDFPKKGIEFKDVLEILQYPDIFQDIILKMSSNQFLKKAEAIISIDARGFIFGSAVALESSKPMIVARKPGKLPGQLLTREYDLEYGKNSLSIQVNALKKFNSFVIVDDLLATGGTVKSVSRLIRDQKKKILGLITVVELKSLKGKSKLDFPVHSIVTL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_SYNJA
Sequence: MATQPLSTSLVRFLTAAVSESIRRASEAGQLGSLTLEQAAGVAPTIQIPSDPRYGDYACPTPLGMAKLCRMAPAQIAQTLQKHLDLPGIATEVAGGGYLNFRLGDSFLAERLQELLRLGEDFGKTAAPHPERILLEYVSANPTGPLHVGHGRWAAVGSTLANLLRWTGHQVEREFYINDAGNQMRLLGQSLEVRVRQLQGEEVALPEDAYHGSYLVDIARRLLDQVKAGIRPLPTTPEEYTDFAYAEMLAWQKQTLQQLRTEFDHWFSERRLHAPDPQTGLSAIQQALQELQERGFLYRAKAPRGEDPKPGAEEAVYFKTQEFGDDKDRVVQKADGSFTYLAADIAYHRDKVRRGYQRLINILGSDHHGYIGRLHAAVGAFSPDVKLEILIGQFVKLFKTDPETGEKTEVRMSKRTGNFVSLNDLIDDPEIGVGVDAARWFLLSSSMDSPINFDLDLAVKQTFDNPVVYVHYSHARCCTLLRRLQEEEKVELTNKVTLTEQQKLPYQEPEERALLLRLLALPDELIAAAEERAPHKIIRYAEAIAADFNKFYDNCRILPLLKEDPLLAQARIQLVQATRQVLFNVLTGILGLSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK4_ARATH
Sequence: MSSQICRSASRAARSLLSSAKNARFFSEGRAIGAASVVHATGKVPQYASNFGKSGSGFVSNSWITGLLALPAAAFMLQDQEALAAEMERTFIAIKPDGVQRGLISEIITRFERKGYKLVGIKVMVPSKGFAQKHYHDLKERPFFNGLCNFLSSGPVVAMVWEGEGVIRYGRKLIGATDPQKSEPGTIRGDLAVVVGRNIIHGSDGPETAKDEISLWFKPEELVSYTSNAEKWIYGQN
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.  Shows the highest specificity towards GDP (By similarity).
What are the official names of this protein?
Nucleoside diphosphate kinase IV, chloroplastic/mitochondrial, NDK IV, NDP kinase IV, NDPK IV, Nucleoside diphosphate kinase 4.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen. Mitochondrion intermembrane space.
Protein: Y875_STRTD
Sequence: MKTKIINLVVVTGMSGAGKTVAIQSFEDIGYFTIDNIPPSLVPKVIELLKHSEETDKIALVVDMRSRVFFDEINDILDQLESNEELNFKILFLDATDGELVSRYKETRRSHPLAADGRVLDGIKLERELLSPLKSLSQNVVDTTKLTPRQLRKAISEQFSSKQDQSSFRIEVLSFGFKYGLPLDADLVFDVRFLPNPYYDPTLRNLTGLDKEVYDFVMTHKESEDFYKNLNHLIKPILPGYQKEGKSVLTIAVGCTGGQHRSVAFAHRLAQDLKNDWTVNETHRDKDRRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein STER_0875.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: TDH_AERS4
Sequence: MKALSKLKAEVGIWMTDVPAPELGHNDLLIKIRKTAICGTDMHIYNWDEWAQKTIPVPMVVGHEYVGEVVAVGQEVRGFAVGDRVSGEGHITCGHCRNCRAGRTHLCRNTIGVGVNRPGSFAEYLVIPAFNAFKLPDNIPDELAAIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVCRHVGARHVVITDVNEYRLELARKMGATRAVNVSKEKLADVMSALGMTEGFDVGLEMSGVPSAFQDMIDKMNHGGKIAMLGIPPSTMAIDWNKVIFKGLFIKGIYGREMFETWYKMASLIQSGLDLTPIITHHFHIDDFQQGFEAMGSGKSGKVILSWDK
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNS1_GIBZE
Sequence: MGESDAYYNGGQQQQYNGGYQQQYQPQPPAASYQAPPQQPYQQQPYQQGPPQNGTGNGNGYMPAQGYNANEKGSFDEQFKIAKPKYNDLWAGILLILVFAGFVVVSGLALQGYSANKGNAGDGIYNNKNDFSPNTSTVILFMFVLAVAFVLSYAYVWMARLFPKQFIWVTGILNVCWAIGTAIFYLWRKYWSAGIVFLIFGLFMAFCFWTWISRIPFSALMLKTTIDVSKKYGHVYLVSLIGGIIATAFSAWYAITLVGIYVKYQPAQDNPSCADGGCGKGKVIGLIAFITFAMYWFSEWLKNTIHTTIAGVYGSWYFNPHNFPKDATRASAKRALTYSFGSIALGSLLVAIIQFLRQICNAARNQEGADGSFVGYAIFCCISCLLGLLEWAVEFINRYAFCHIALYGKAYFAAAKDTWKMIKDRGIDALINDCLIGPVLSFGALFIAYACALLAYLYLYFTDPAYNSDGQYTAVVMAFSFLIGFQIANVFTTPISSGIETIFVAAGWDPQVMWRDHPELYNEMVRVYPKVQQVIKDR
What is the function of this protein?
Probably involved in transport through the plasma membrane.
What are the official names of this protein?
Protein PNS1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL18_CAMJR
Sequence: MRANVLKRKLTLRIKRKKRIRAKISGCENFPRISVFKSNRTLYIQAIDDVKAVTLAAVDGRKLGVKANKEGAKKIAAEFAKTLKAKKIEQAVFDRNGYVYHGVIAALAESLRENGIRL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: FDB21_FUSPC
Sequence: MVSPDNRPGTQGPSASAHAHDSRVPRKRPGSWDNNPSTAGNRAVKKRAVRACVSCRDRKVRCDVVNGGPPCTNCRLDDVDCVLKASNRGKHNPARYQARSRLSSNATAPRAPSPSDNINTDADTAAPGPAPGSASATVFRSDHSHGSVATGQPQERRGSQSVAHGDEETICDDDENENNSWHNQQEAEQTRIIHDSQVQPNDIVHETHCEQQPQPQPSQGAATRSTPSAQPANPQTSDYLVALAFQGFYALGWTEQDATEAPPSSSRMDNVSASANTPHADQNHLPLYISPHPSHLDKHDLEFLARKDCLTIPDNQLRDELIRIYVFVVYPFMPAIDLVDFLEPITGSSEVGTVSLLLFQAIMFASVTFIDMQLLQRYGFKNKRAARQVFFNRVKLLYSLGYEADRLTLVQSLLLMTYWYDSDSDEKHTWYWMGLALTTAHIEGLQRDLEEPQQMTKNGRLRRRIWWSCVIRDRLLGLGLRRPSRIQEDEFSVERLRLDDFDISLPPPPAVARLLAAPSYTGKDPVNRQRMANLCIDLSQLCFTIGRILHTQYTIASTPGAGSNYLRRAIVRPRSLKEQAHSFAKCDADLQEWFRSLAPESRYVPGARDGGAAAAQVENSTIRLHKILLYMKYLTAIGALHRPQVFYSGSDSIDPARKADSRRKLTEAAVAITKLAFDLQSNGQMCYAPTSSVPAFLSAALIHLLNIRSPDEETRNISIGRFCQCLDALHQLQSMYTAADEAVHIINNMTENAGFILPLLGIGNPMSKANGIAARNSRLFSAIGPSRVTTAYPSPAPATGNLDTSQEEMISAPIPGAGPTGVALTGQRSRQPSAGPNMTPSATPNLMSIWSAAGNIHSERDLPLPADLMAGIQLDLDAWYNIGDIIDPALMNFETGLDFLNS
What is the function of this protein?
Transcription factor; part of the Fusarium detoxification of benzoxazolinone cluster involved in the degradation of benzoxazolinones produced by the host plant (PubMed:25727347, PubMed:26828593).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (By similarity).  FPSE_08121 positively regulates the expression of the FBD cluster gene FPSE_08120 in response to 2-aminophenol (2-AP) treatment and contributes quantitatively to benzoxazolinone tolerance (PubMed:26828593).
What are the official names of this protein?
Transcription factor FPSE_08121, Fusarium detoxification of benzoxazolinone cluster protein FPSE_08121, FDB cluster protein FPSE_08121.
What are the subcellular locations of this protein?
Nucleus.
Protein: NS49_CVBLS
Sequence: MTTKFVFDLLAPDDILHPSNHVNLIIRPI
What are the official names of this protein?
Truncated non-structural protein of 4.9 kDa, Truncated ns4.9, Truncated 4.9 kDa accessory protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns4.9 protein family.
Protein: COPG1_RAT
Sequence: MLKKFDKKDEESGGGSNPLQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAVERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLYHVRKNDRLAVSKMISKFTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTNNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKALNAGYILNGLTVSIPGLEKALQQYTLEPSEKPFDLKSVPLATTPMTEQRPESTSTAAVKQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFSDHLVFQFDCTNTLNDQTLENVTVQMEPTEAYEVLSYVPVRSLPYNQPGTCYTLVALPKEDPTAVACTFSCVMKFTVKDCDPNTGEIDEEGYEDEYVLEDLEVTVADHIQKVMKVNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPENKNTHTLLLAGVFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIILASVG
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.  Required for limiting lipid storage in lipid droplets.  Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis (By similarity).
What are the official names of this protein?
Coatomer subunit gamma-1, Gamma-1-coat protein, Gamma-1-COP.
What is the protein family that this protein belongs to?
Belongs to the COPG family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it (By similarity). About 70% of the COPG1-containing coatomers are found in the cis-Golgi apparatus.
Protein: CLC2_CAEEL
Sequence: MSQAVSYAILVLTIIAFLLTAAALCTPAWQVVYAREIRQWVQSGLWLSCQTRPNGMYSCTYTFSHDDFNTYFSDEVSGFRTPSFYPWQRTLFHIYLISQAFAMLSLISFCVSVSHKESKMPNILRSVFLVLAAVIAFGCLIAFAVYSYMVEYRFFHVSVSGIYEKHRGYSWYIALTGAFVYLVAIILSVVHVLLQARNSNTTMSRQNINSSLQSDFFEYQYHPNRSMESFEDRFAMRTLPPVPRQEKKTTVF
What are the official names of this protein?
Clc-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the Clc family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RF1_SERP5
Sequence: MKPSIVAKLEALQERHEEVQALLGDAGVIAEQDRFRALSREYAQLTDVSRCFLEWRKVQDDLATAEMMLDDPEMREMAQEELKDAKAATEELEQQLQVLLLPKDPDDERDCFLEVRAGTGGDEAAIFAGDLFRMYSRYAETRRWRVEIMSANEGEHGGYKEVIAKVSGDGVFGQLKFESGGHRVQRVPETESQGRIHTSACTVAVMPAVPEAELPEINAGDLKIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKAMSVLGARIRAAEMAKRQQAEASTRRNLLGTGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIQPIVQEYQADQLAALSAEPE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LNT_GEOMG
Sequence: MDYRRLRMPDFDAIPRRDYLMAVLSGVLLALSFPSPGISPLAWIAFAPLLLACGRKDPRKAFRLGFVTGLAAYAGILYWITIVVTTYGKLPWIVSVGVLSMLVSYLALYPAVVAYLVRRGEERGISLLISFPLLWVGLEYGRAFLVTGFPWASLGYTQYRTLPLIQIADITGVYGLSFLIALANVVLFRIIRGFAAREPAPYPVKSVVLLLVLLLVTIAYGFKRLHVPEGGAPFKVALIQGNIDQNIKWDPSFQEETVAIYERLSRKACAAGPSDLLVWPESAAPFYFQDEPRYASRIKGLARELKTCAVVGSPAFEKDGERLKYLNSAFLLSPWGDVIGRSDKIHLVPFGEYVPMAKLLPFVNKLVAGIGDFSPGAQIAALDTGKGRIGILVCFEGIFPELSRAYVRAGSRLLVNITNDAWFGRSSAPYQHISMTVFRAVENRVPLVRAANTGITSIIDSRGHIRGMTPLFQEAVLNGEVRLGEGESFYNRYGDVFAWACVAGAAVVAALAFRRKSIHHQ
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LSPA_CYAP4
Sequence: MNFKNTFFWFTALLSLLLDHLTKLWVVKNFALTVPPQTIPLWPGVFHLTYVTNTGAAFSLFSQGGEWLRWLSLGVSVGLMALAILGPNFNRWEQAGYGFLLGGAAGNGIDRFVAGRVVDFLDFRLIGFPIFNLADVFINIGIICLLIAAWGPLPSRRRAERRPSSPPPSDKLP
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.