PharMolix/UniProtQA huggingface dataset:
Protein: DGKH_DROER
Sequence: MAHLKLDTLHVQRSPRGSRRSSPSSGRSSACSSGSISPVPIIPIISISHDGDESESESEIETEPVRLFQRRMSTKCTNNLAAIIKEGFLLKHTWSFQRWRRRYFRLKRNMLFYAKDEKCDVFDDIDLSDLCYFECGIKNVNHSFQIITPTRSLVLCAESRREMEDWLGGLKTATAPQRPRGDSFLIEQHDILSNHHHWYATSHARPTYCNVCRDALSGVTSHGLSCEVCKCKVHKRCAAKSIANCKWTTLASVGKDIIEQADGSIIMPHQWMEGNLPVSSMCAVCKKTCGSVLRLQDWRCLWCRATVHVACRPQMAVACPIGPAKLSVVPPTSVHSISTDDAWDVASPKGNFSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLISTGPSLGLRLFRHFEMFRILVCSGDGSVGWVLSEIDRFNMHKQCQVAVMPLGTGNDLARVLGWGSSCDDDTHLPQILERYESASTKMLDRWSIMVFEKAIPVPKTPKMSISTEQEAMLTGMVTSANHHLRFIVETNDTQTLISSTRNLCDTVDDLVCRISEHHKEDEQLAVKCDILRQKLNMLLDALQEEEIGAHSGDDLIATIRSLITRSIPVTPGSNAYLLNPNISIEKTEKDQINTKERRNSRSLRSSEKEALQCRANSVKRAIYNVVEHSEPGRPKRYQRKLSITPFEALKLPTTASGESTPCTSPLPIIPPINIISPTMETSRLTCISPLPDTRRDSVDENFFNSINLPAPRQFADSRRSSGVPEVIQEIEEGANGETVYRRSRMSLTGGANIDDAGNRLSPCSDGGENTPTERKVDFLRVPIHTGEPIVDPLCDYRPHEVFERTYYMTREMDKDKEKDKEKEKEKTAEIEEENDKCVEKLGSIPAEKLVHTCNLQVPGVVVTPNPQNVYSSASITIIDTDAQTTTEQSSSDDLGGEASDVLSAISNEECSVASEIFDKQDAGQTVGDIIQNMDASNFTHIDSPETSDETEAMPGESLMDDISSVLGHDITYALQDNTLTDDTTTLCSEHAGPPKPPRKKSLSALSRTQAHPRRRNSSPPRTARLARMDSDDNPQQFGFENIVFEIDNRCDDQKMREPPRYCSLAQFVEGNDIARQSFKQLMLEQHRGGDNDIESPEQQQAPTNKGAHLLATTSEDELSTQTAIKIEIHDIDATVRSINSSMKPNTILTTSTSPTKKSGHGQDISVVVRPPTPLRGDSIKPTVSLLPVSSGGAMAVSMTCSGMLGVRAMNASEIRRHSSHAPSLAVREFDKDKDRRHSGFNPNQLTLDPEHARFLSSSPAASRRISCGSLFKKKNKKIATKRSYGLFSVRFFVVAEPDFRLATLALIRPLIPLPNEALPNLQTLKGSKSSLFMGSTLFGFDHLASAERDKEERGGKDKDKTPTEEANRKLPIINPLVRLPNWPNLANGGGFISKCLLANADTLCAAVSPLMDPDETLLAGYHEKCVMNNYFGIGIDAKISLDFHNKREEHPEKCRSRARNYMWYGVLGSKQLLQKTCKNLEQRVQLECDGQRIPLPELQGIVILNIPSFMGGTNFWGSSTKKDDIFLPPSFDDRVLEVVAVFGSVQMAASRLINLQHHRIAQCQSVQINILGDEEIPIQVDGEAWLQPPGMIRILHKNRVQMLCRNRSLELSLKSWHEKQRQHSISIQRDASSTASEHANSTDEVISERECYVLLNFIEAVSSLVKWVKFLIISHPALQHDLYEVACRASEALESIHPQGKLLEGPSLRTKLVEVIDSSRQLYDDACTLLRDRGHSLILREDLETKLSAALANMEMELKKCSVQKCIDGKLRAYFNVLAPNEESDGRRKSRPFWVRLRSGSTAGQQVFKPPLTNTREAANNWSVNEVVTWLETMQLSEYVDSFLKNDIRGKELLTLGRRDLKDLGVVKVGHVKRILQAIKDLSEN
What is the function of this protein?
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).
What are the official names of this protein?
Diacylglycerol kinase eta, DAG kinase eta.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_NITWN
Sequence: MIIAIDGPAASGKGTLGKRLAAHYHFRHLDTGVIYRAVAKALLDAGADPADEARAIAAALELDPERFGHPALKARAIGEAASVVSTFPKVREALLTFQRQFAAEPPGAVLDGRDIGTVICPNADVKIFVEADPVVRARRRTLEARARGEEVDEAVVLADILKRDERDRNRPVAPLKAAADAHVLDNSNLDIEAGLKAAIAIVESVRVRSGRA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AR2BP_BOVIN
Sequence: MDALEEESFALSFSSASDAEFDAVVGYLEDIIMDDEFQLLQRNFMDKYYQEFEDTEENKLTYTPIFNEYISLVEKYIEEQLLERIPGFNMAAFTTTLQHHKDEVAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRGLDLSSGLVVTSLCKSSSVPASQNNLRP
What is the function of this protein?
Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3.  May play a role as an effector of ARL2 (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 2-binding protein, ARF-like 2-binding protein, Binder of ARF2 protein 1.
What is the protein family that this protein belongs to?
Belongs to the ARL2BP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body. Note=Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules (By similarity). In retina photoreceptor cells, localized in the distal connecting cilia, basal body, ciliary- associated centriole, and ciliary rootlet. Interaction with ARL2 may be required for cilia basal body localization (By similarity). The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria.
Protein: ATPH_HETA4
Sequence: MDSIISAASVIAAGLSVGLAAIGPGIGQGNAAGQAVEGIARQPEAENKIRGTLLLSLAFMEALTIYGLVVALSLLFANPFTS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FIS_PHOLL
Sequence: MFEQRVNSDVLTVATVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: CATP5_CAEEL
Sequence: MNTSEREPLLDTTTRNRVYDTTDNPSTKIMKREKDNPKAKTTSFNQGKLNIGEETCDLYAYKETIGRQILFWLLTIVTLGFYQLLAYWVKSLFVKVRFQPTSHDECEYVMVEDIHGTQTIKEVFKAESDVGLARPTRSGKQEKVKVMRFFTYRKIKYIWYEKDQEWLNPADMDSAAPFNIYQKLTLDVIGLKEQDVIASRKIYNMNALALALTPILVILFKEVLGPFYLFQCFSVALWYSDNYAYYASVIVIITVGSAAVAVYQMRAQEKRIRNMVGDTISVIVRRDGHDITIDASEIVPMDILILPSNTFILPCDCLLMNGTVIVNEAMLTGESVPVTKASLKEADECGPEIRLSSEHNRHTLFSGTTVLQTRNYKGQPVMARVIRTGFSTLKGQLVRSIMYPKPQEKEALKDVMVFILVLGFIALIGFIYTVIEMVSRGESLKHIIIRSLDIITIVVPPALPAAMSVGIINANSRLKKKKIFCTSPTTVNVCGLINVACFDKTGTLTEDGLDFNCLKAIRKNEDGKPEFTSEFEELDPVKLSAENANLNIVVAAASCHSLTRIDGTLHGDPLELILVEKSKWIIEEAVNSDEETQDFDTVQPTVLRPPPEQATYHPENNEYSVIKQHPFNSALQRMSVIISTPSEHSAHDMMVFTKGSPEMIASLCIPDTIPEDYMEVVDEYAQRGFRLIAVASKAVHLNFAKALKTPRDIMESELEFLGLIVMENRLKDVTLSVINELSVANIRCVMVTGDNLLTAMSVARECGIIRPTKKAFLITHSKTEKDPLGRTKLFIKESVSSSENDIDTDSEVRAFDRKAVLRTATYQMAIAGPTYSVITHEYPELVDRITAMCDVYARMAPDQKAQLIGALQEIGAKVSMCGDGANDCAALKAAHAGISLSQAEASIAAPFTSNVPDIRCVPTVIKEGRCALVTSYAVSKYMAAYSLNEFLSVMLLYNDGTNISDGQFLYIDLVLITLVALFLGNTEASRKLSGIPPPRRLATSAFYFSVFGQMFFNIITQTTGYLLVRGQSWYVPNPEELDNTTTMIGTTVFFTSCCMYLGYAFVYSKGHPYRRSVFTNWLLCGIIFVIGAINMVMIFTNMGFLMNLMGFVYVPSTSMRFILLAISLAGVFLSLLYEHFFVEKVVAIHFESYLRQRRLRNGDPSLSAYEKILAAIGSSPRWFEDEINLSKSIDRKETIESKC
What is the function of this protein?
Involved in the uptake and/or transport of polyamines, probably through ATP hydrolysis.  This contributes to the maintenance of intracellular polyamine levels.  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
What are the official names of this protein?
Cation-transporting ATPase catp-5.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.
Protein: FRLD_ECOLI
Sequence: MKTLATIGDNCVDIYPQLNKAFSGGNAVNVAVYCTRYGIQPGCITWVGDDDYGTKLKQDLARMGVDISHVHTKHGVTAQTQVELHDNDRVFGDYTEGVMADFALSEEDYAWLAQYDIVHAAIWGHAEDAFPQLHAAGKLTAFDFSDKWDSPLWQTLVPHLDFAFASAPQEDETLRLKMKAIVARGAGTVIVTLGENGSIAWDGAQFWRQAPEPVTVIDTMGAGDSFIAGFLCGWSAGMTLPQAIAQGTACAAKTIQYHGAW
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of fructoselysine to fructoselysine 6-phosphate (PubMed:12147680).  Functions in a fructoselysine degradation pathway that allows E. coli to grow on fructoselysine or psicoselysine (PubMed:12147680, PubMed:14641112).  To a much lesser extenst, is also able to phosphorylate psicoselysine (PubMed:14641112).
What are the official names of this protein?
Fructoselysine 6-kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: HBA2_NOTNE
Sequence: SLSTKDKETVKAFWSKVSGKSEDIGNDALSRMLVVYPQTKTYFSHWKELTPGSAPVRKHGMTVMKGVGDAVSKIEDLTAGLMELSELHAFTLRVDPANFKISHNILVVFAIMFPKEFTAEVHVSMDKFLAALARALSEKYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-2, Alpha-2-globin, Hemoglobin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YB47_YEAST
Sequence: MGVKQTPPVQVKVSDADSTNRRKSSSQEGNPQLVQLKAKSDKDKRKGSSDSTASIMGSSNALPTKNLTTPPALNPLTTSISRGNTAYERSVNGSRITMHSNLAPTETQDVSWSEIDTLDDVKKMAKEPIVNDGFPRDFESNLTQMRKSHAQLLRLMRERNQRLKYAKLRSPPHKDQHNSATNKDQEPDEVLHDPEIALDGEKYVSQVVDTIKDVHRC
What are the official names of this protein?
Uncharacterized protein YBR197C.
Protein: END3_VANPO
Sequence: MPKLEQFEIKKYWQIFSGLKPVENKVNHDQVLPILYNSKLDSSILNKIWFLADIDDDDNLDFEEFVICMRLIFDMVNKNIDKVPDELPDWLIPGSKAKLVKERKQRKQIENADIPKVETPKIDWYISPEDKKSYENILSGIQTATDGSYSYSSTTLVLKSKFFNIGTSDFEKTWKLVNPKNFASIDKDPTLYFIHILRQRNDLGCNIPSELPKALLDSFSKERVTYDLNSNQSQVTRSSNVRSNTNMSQHTIEAIRMNEIPRGNPNDAASLEIELNSLDAELNRIRDEITRQEDTILIREQFEGLLSYKEQQYQKSKQSSMSPVKLNAKSISDDLSNIEQQVGVLENYLADKKVELQQLESQIQSVNK
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein END3, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: MURA_CHLTR
Sequence: MPGIKVFGETVLRGSVRVSGAKNATTKLLVASLLSDQRTILKNVPNIEDVRQTVDLCRVLGAIVEWDQQAQVIEIHTPRILLSKVPPQFSCVNRIPILLLGALLRRCPYGIFVPILGGDAIGPRTLHFHLEGLKKLGAEIVISDEGYWASAPNGLVGAHITLPYPSVGATENLILASVGAQGRTIIKNAALEVEIIDLIVFLQKAGVEITTDNDKTIEIFGCQDFYSVEHSIIPDKIEAASFGMAAVVSQGRIFVEQARHEHMIPFLKVLRSIGGGFSVHENGIEFFYDKPLKGGVLLETDVHPGFITDWQQPFAVLLSQSEGCSVIHETVHENRLGYLKGLVKMGAHCDLFHECLSAKSCRYSTGNHPHSAVIHGPTPLQATDLVIPDLRAGFAYVMAALIAEGGASWIENTEMLDRGYTDWRGKLERLGAKVLARDSVSVYV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_RHIWR
Sequence: MSSPEISIKLKRLDHGAGLPLPAYATAHAAGLDVVSAEDVTLAPGARHAVATGFAIAIPEGYEVQVRPRSGLALKHGVTCLNTPGTIDADYRGEVKVILANLGSEPFEVKRGERIAQLVPAAVQRAAFAEVSDLDETARGAGGFGSTGR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL27_SHEHH
Sequence: MAHKKAGGSTRNGRDSESKRLGVKRFGGESVLAGNIIVRQRGTKFHAGVNVGIGRDHTLFALTDGKVKFEVKGPQNRKFISIED
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ACCD_CHLPD
Sequence: MVWFKRAKPAIRTTDRRDMPEGMWWKCDECGAMLHKKQLEDNFYTCSECGYHFRISPYKYFSLLFDGDKYQEFEDQLRSADPLGFTDTKKYLDRVHDIIEKSGKTEACRNAFGEADGRMLVVSAMDFGFIGGSMGSVVGEKIARAVDKAIDLNAPLLVISQSGGARMMEGAFSLMQMAKTAARLTRLSEKKLPFFSLMTDPTMGGITASFAMLGDVNISEPKALIGFAGPRVIRDTIKRDLPEGFQRAEFLLEHGFLDLIVHRRELKTQIVRLMTMLAP
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_AGRRK
Sequence: MSSFLHDSPVLEAPPIPFDNSYARLPPQFFAEQAPTPVAAPRLIKFNSVLASELGLDAEVLERDGAAIFSGNALLPGSQPLAMAYAGHQFGGFVPQLGDGRAILLGEVIDRNGRRRDIQLKGAGPTPFSRRGDGRAALGPVLREYIVSEAMFALGIPTTRALAAVTTGQPVYREEALPGAVFTRVAASHIRVGTFQYFAARGDTDSLRILADYVVDRHYPEIKDRKNRYLALLDAVADRQAALIARWLHVGFIHGVMNTDNMTISGETIDFGPCAFMDAYDPATVFSSIDRQGRYAYANQPAIGQWNLARLGETLLPLIDPTLDTAVELANGIIKAYGERFQTYWLAGMRAKIGLATEEDSDLDLVQSLLAVMQEQEADFTLTFRRLGVLAASVDNEAAFAASFKDPLSVAPWLSLWRERLGRDPQSPAARAKAMLGVNPAFVPRNHRIEQAIAAAVEEDDFSLFEALLAVLAKPYEDQPAFAPYAEPPRPAERVLQTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RL11_NATTJ
Sequence: MAKKVAQVIKLQIPAGKATPAPPVGPALGQHGVNIMSFCKEFNEQTANQEGMLIPVEITVYEDRSFTFITKTPPAAVLLKKAAGIDKASGEPNKNKVATVGKDKVKEIAELKMQDMNASDLDAAMKMVEGTARSMGIIVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: TRPB_ECO7I
Sequence: MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETDVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ATPL_RICPU
Sequence: MDMVSLKFIGTGLMAIGMYGAALGVSNIFSSLLSSIARNPSATENLQRMALIGAGLAEAMGLFSFVIAMLLIFS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VATL2_CANGA
Sequence: MDMVASDNVYAPLYAPFFGFAGCALAMILSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEEYTLFNGFMHLSCGLCVGFACLSSGYAIGIVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIIALILNTKGSE
What is the function of this protein?
Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit c', V-ATPase subunit c', Proteolipid protein VMA11, V-type proton ATPase 16 kDa proteolipid subunit 2, V-ATPase 16 kDa proteolipid subunit 2, Vacuolar proton pump 16 kDa proteolipid subunit 2, Vacuolar proton pump c' subunit.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: METF_BUCAP
Sequence: MNFLHQYYQDIIKKKLENLNDKIQCSFEFFPPKNLDTEKKLFSSVVKLSLLKPFLFSVTYGANSGERKKTYSIVQRIHKKTGITTAPHLTCVDASLSELKEIAKFYWENGIRSIVALRGDVPNKSYQHKIYALDLVVLLKKIADFDISVAAYPEIHPESKNAQSDILNLKKKADAGANRAITQFFFNVESYLRFRDNCIKNNINIEIIPGILPIYNFEQLKKFSSMTNVSIPKWMFEMFNGLDEDLETQKIIGSNIVINIVKTLLYEGVKNFHFYTLNKSDVIYSICHMFGL
What is the function of this protein?
Catalyzes the NADH-dependent reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate.  Is required to provide the methyl group necessary for methionine synthetase to convert homocysteine to methionine; the methyl group is given by 5-methyltetrahydrofolate.
What are the official names of this protein?
5,10-methylenetetrahydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the methylenetetrahydrofolate reductase family.
Protein: PMT1_YEAST
Sequence: MSEEKTYKRVEQDDPVPELDIKQGPVRPFIVTDPSAELASLRTMVTLKEKLLVACLAVFTAVIRLHGLAWPDSVVFDEVHFGGFASQYIRGTYFMDVHPPLAKMLYAGVASLGGFQGDFDFENIGDSFPSTTPYVLMRFFSASLGALTVILMYMTLRYSGVRMWVALMSAICFAVENSYVTISRYILLDAPLMFFIAAAVYSFKKYEMYPANSLNAYKSLLATGIALGMASSSKWVGLFTVTWVGLLCIWRLWFMIGDLTKSSKSIFKVAFAKLAFLLGVPFALYLVFFYIHFQSLTLDGDGASFFSPEFRSTLKNNKIPQNVVADVGIGSIISLRHLSTMGGYLHSHSHNYPAGSEQQQSTLYPHMDANNDWLLELYNAPGESLTTFQNLTDGTKVRLFHTVTRCRLHSHDHKPPVSESSDWQKEVSCYGYSGFDGDANDDWVVEIDKKNSAPGVAQERVIALDTKFRLRHAMTGCYLFSHEVKLPAWGFEQQEVTCASSGRHDLTLWYVENNSNPLLPEDTKRISYKPASFISKFIESHKKMWHINKNLVEPHVYESQPTSWPFLLRGISYWGENNRNVYLLGNAIVWWAVTAFIGIFGLIVITELFSWQLGKPILKDSKVVNFHVQVIHYLLGFAVHYAPSFLMQRQMFLHHYLPAYYFGILALGHALDIIVSYVFRSKRQMGYAVVITFLAASVYFFKSFSPIIYGTPWTQELCQKSQWLSGWDYNCNTYFSSLEEYKNQTLTKRESQPAATSTVEEITIEGDGPSYEDLMNEDGKKIFKDTEGNELDPEVVKKMLEEEGANILKVEKRAVLE
What is the function of this protein?
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity.  Forms a heterodimeric complex with PMT2 and more rarely with PMT3 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins.  The PMT1-PMT2 complex participates in oxidative protein folding, ER-associated protein degradation (ERAD), as well as ER export.  Required for incorporation of proteins in the cell wall.
What are the official names of this protein?
Dolichyl-phosphate-mannose--protein mannosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YFCN_ECOSE
Sequence: MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPVKRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVEEWLPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: SPED_DESHY
Sequence: MEVKPLKKLKLYGFNNLTKTLSFNMYDICYAKTPEHRDAYIQYIDEEYNAQRLTSIVTEVARIVGANILNIAKQDYDPQGASVTMLIAEEHLGPENPDDNPFDPVYTDKEGPLPDAVVAHLDKSHITVHTYPESHPHGGISTFRADIDVSTCGQISPLKALNFLIESFAPDIIVADYRVRGFTRDVDGKKVFIDHKINSIQNYVDRKYRDLYQMIDVTVFQEYIFHTKMILKDFDLDNYLFGTAKKELSINDKRKIKQRLKKEMAEIFYGKNMPRM
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: DUT_ACIBT
Sequence: MKVQVKLLDPRLGKEWPLPSYATAGSAGLDLRACLDEAIEIEPGQTVLVKTGMAIYIHDVNFAGLILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSVWNRGQTTFRLEPGERLAQYVLVPVVQAEFEQVEEFEETLRGAGGFGHTGKQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PYRD_LEGPL
Sequence: MYSLLRPLLFRLDAEKAHSLTLSLLHYLPGFYFRKMAGQPVHAMGLVFPHQVGLAAGLDKNGEHLDALAKLGFSFIELGTVTPKGQTGNPKPRLFRIAEANAIINRMGFNNSGVDVLVENVKSANYKGILGINIGKNKETNLNQAADDYLYCFRKVYDHASYVTINISSPNTPDLRQLQQGDYFAELLAQLQKEQIKLADQYGRHVPLVVKVSPDETDETLKQMTDIILQYGIEGIIATNTTCSREMVKNLPCSEEQGGLSGRPLMELSTRCLRLLKQYVGNDVTLIGVGGIDSLESAKDKINAGASLLQVYSGLVYKGPELIHDIVSGLNAV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: UBID_ACTP2
Sequence: MKYKDLREFLTLLEGQGELVRIKQEIDPYLEMAEISDRTLRKGGPAILFENPKGYRMPVLCNLFGTPKRVALGMGQEDTHALRELGKLLAFLKEPEPPKGFKELIGQLPQWKQVLNMPSKVLGKADCQQVVLSGDEVELYKLPIMHCHEGDVAPLVAWGLTITQGPYKKRQNLGIYRQQLIGKNKLIMRWLSHRGGALDFHEWKEANPDKPFPVSVAIGADPATILAAVTPIPDTLSEYAFAGLLRGQKTEVTKSISNDLEVPASAEIVLEGYIDPNETALEGPYGDHTGYYNEQEYFPVFTVTHITMRRDAIYHSTYTGRPPDEPAVLGEALNEVFIPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWKDVIWAITTRCDPSRDTTLIDHTPIDYLDFASPIAGLGSKMGIDATNKWPGETSREWGTPIKKDPNVVKRVDEIWDQLGL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS21_CAEEL
Sequence: MQNDAGQTVELYVPRKCSSSNRIIGPKDHASVQIDFVDVDPETGRMIPGKSTRYAICGAIRRMGESDDAILRLAQKDGLVPRDDVKSN
What are the official names of this protein?
40S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).