PharMolix/UniProtQA huggingface dataset:
Protein: EIF1A_MACFA
Sequence: MSQATKRKHVVKEVLGEHIVPSDQQQIVRVLRTPGNNLHEVETAQGQRFLVSMPSKYRKNIWIKRGDFLIVDPIEEGEKVKAEISFVLCKDHVRSLQKEGFWPEAFSEVAEKHNNRNRQTQPELPAEPQLSGEESSSEDDSDLFVNTNRRQYHESEEESEEEEAA
What is the function of this protein?
Plays a role into cellular response to oxidative stress.  Decreases cell proliferation (By similarity).
What are the official names of this protein?
Probable RNA-binding protein EIF1AD, Eukaryotic translation initiation factor 1A domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the EIF1AD family.
Protein: PHT12_PETHY
Sequence: TARYTALVAKDAKRAAADMGKVLHVEIDPEDAKVERMAKDESNQFGLFSWEFVRRHGLHLFGTCSTWFLLDIAFYSQNLFQKDVFTAIGWIPPAKTMNAVQEVYKIARAQTLIALCSTVPGYWFTVAFIDIIGRFAIQLMGFFFMTVFMFAIAIPYHHWTLQENRIGFVIMYSLTFFFANFGPNATTFV
What is the function of this protein?
Low-affinity transporter for external inorganic phosphate (Pi).
What are the official names of this protein?
Low affinity inorganic phosphate transporter 2, PhPT2, PhPht1;2, Arbuscular mycorrhiza-induced phosphate transporter PT2, AM-induced phosphate transporter PT2, H(+)/Pi cotransporter PT2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y049_UREPA
Sequence: MKKNKSNLTPTTNYFDVFNTYKEKKASVDLITYEELMASVLFDNKLGFESEVYLDFVKKFTLAFEKKLDIWFENFIINFNLNLKFSTTIMIPILVTKANSTTDAINFRNDQNPVYNNFLISYNQKIKKLLLQNHPVQILPHLILFKSNLNGSLVLVFSEKIIASIEQKSGN
What are the official names of this protein?
Uncharacterized protein UU049.
Protein: SIM1_PANTR
Sequence: MKEKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVFPEGLGEAWGHSSRTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIYEYIHPADHDEMTAVLTAHQPYHSHFVQEYEIERSFFLRMKCVLAKRNAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCAHHLLLVKGQVTTKYYRFLAKHGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQISASKPAFSYTSSSTPTMTDNRKGAKSRLSSSKSKSRTSPYPQYSGFHTERSESDHDSQWGGSPLTDTASPQLLDPADRPGSQHDASCAYRQFSDRSSLCYGFALDHSRLVEERHFHTQACEGGRCEAGRYFLGTPQAGREPWWGSRAALPLTKASPESREAYENSMPHIASVHRIHGRGHWDEDSVVSSPDPGSASESGDRYRTEQYQSSPHEPSKIETLIRATQQMIKEEENRLQLRKAPSDQLASINGAGKKHSLCFANYQQPPPTGEICHGSALANTSPCDHIQQREGKMLSPRENDYDNSPTALSRISSPNSDRISKSSLILAKDYLHSDISPHQTAGDHPTVSPNCFGSHRQYLDKHAYTLTGYALEHLYDSETIRNYSLGCNGSHFDVTSHLRMQPDPAQGHKGTSVIITNGS
What is the function of this protein?
Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.
What are the official names of this protein?
Single-minded homolog 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAUE6_ARATH
Sequence: MKTLFVLFILILCVFAINANQQEEINQESTQQTHQNLLYKVQKWRTSLKDSSDAELKLSPALVVAGVLCFTAALISSASGIGDGFFFIPIMNLVAGIDLKAASSFSAFMVTGGSIANLINNHFGCKKLIDYDLALLLEPCMLLGVSVGVICNKVFPEWLITGLFVVFLMWSSMETCENGHTSWKLSLILREKEDMRDSRLAEVKRRRTIIFFKHLYLKIKKTETKQSFLGRNLGIISIKPCSVEYWILLSLQIPLALVFTILALSRTESLQEQSISNQEGTRLDHQFKRLMFPVMSFLAGLLGGIFGIGGGMIISPLLLRAGIPPQVTAATTSFMVFFSATMSGVQYLLLGMQNTEAAYVFSVICFFASTLGLVFAQKVVPHFRRASIIVFLVGTMMYLTTIVMASFGILVFYIDNDAGKDIGFQLPC
What are the official names of this protein?
Sulfite exporter TauE/SafE family protein 6.
What is the protein family that this protein belongs to?
Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: B2MG_FELCA
Sequence: MARFVVLVLLGLLYLSHLDAVQHSPKVQVYSRHPAENGKPNFLNCYVSGFHPPQIDITLMKNGKKMEAEQTDLSFNRDWTFYLLVHTEFTPTVEDEYSCQVNHTTLSEPKVVKWDRDM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SCTL_YERPS
Sequence: MSQTCQTGYAYMQPFVQIIPSNLSLACGLRILRAEDYQSSLTTEELISAAKQDAEKILADAQEVYEQQKQLGWQAGMDEARTLQATLIHETQLQCQQFYRHVEQQMSEVVLLAVRKILNDYDQVAMTLQVVREALALVSNQKQVVVRVNPDQAGAIREQIAKVHKDFPEISYLEVTADARLDQGGCILETEVGIIDASIDGQIEALSRAISTTLGQMKVTE
What is the function of this protein?
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (By similarity).  Acts as a regulator of the YscN/SctN ATPase activity (By similarity).
What are the official names of this protein?
Type 3 secretion system stator protein, T3SS stator protein, Low calcium response locus protein KC, Yop proteins translocation protein L.
What is the protein family that this protein belongs to?
Belongs to the SctL stator family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFT_ALKPO
Sequence: MFQNVIIGQYVQGNSFLHKLDPRSKLISVFILLIIIFFADNWFSSLLLVGLTVMLMAISRVPLLFLYRGLRPILWLVLFTLILHILLTKEGPVLMTLGPIAIHEGGVMNGLFIATRLLTLVMLTSLITLTTSPIDLTDGLESLFTPLKKVGLPAHELALMMSIALRFIPTFMQETEKILKAQMARGVDFSSGPISKRVKALLPLLVPLFISAFKRAEDLALAMEARGYRGGEGRTKLRVLMWNGKDSFVVVSALVIGVGIILLRNG
What is the function of this protein?
Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter transmembrane protein EcfT, ECF transporter T component EcfT.
What is the protein family that this protein belongs to?
Belongs to the energy-coupling factor EcfT family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENO_CORA7
Sequence: MADIIHVMAREILDSRGNPTVEAEVFLDDGARGVAGVPSGASTGVHEAHELRDGGDRYLGKGVLKAVENVNEEIADELAGFEADDQRLIDQALIKLDGTENKSRLGANAILGVSIAAAKAAAESAGLPLYRYVGGPNAHVLPVPMMNIVNGGAHADSGVDVQEFMIAPIGAESFSEALRIGAEVYHALKSVIKSKGLSTGLGDEGGFAPEAESTKAALDLIIEAIKKAGFEPGKDVALALDVASSEFFKDGKYHFEGGEHTAEEMAKVYEELVAKYPIVSIEDPLQEDDWEGYTKLTETLGDKVQIVGDDFFVTNPARLQEGIDKKAANALLVKVNQIGTLTETFDAVELAHRNGYRTMMSHRSGETEDTTIADLAVALNCGQIKTGAPARSERVAKYNQLLRIEQELGDAAVYAGRSAFPRFQG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: GTOMC_ORYSJ
Sequence: MAHAAAATGALAPLHPLLRCTSRHLCASASPRAGLCLHHHRRRRRSSRRTKLAVRAMAPTLSSSSTAAAAPPGLKEGIAGLYDESSGVWESIWGEHMHHGFYDAGEAASMSDHRRAQIRMIEESLAFAAVPDDAEKKPKSVVDVGCGIGGSSRYLANKYGAQCYGITLSPVQAERGNALAAEQGLSDKVSFQVGDALEQPFPDGQFDLVWSMESGEHMPDKRQFVSELARVAAPGARIIIVTWCHRNLEPSEESLKPDELNLLKRICDAYYLPDWCSPSDYVKIAESLSLEDIRTADWSENVAPFWPAVIKSALTWKGLTSLLRSGWKTIRGAMVMPLMIEGYKKGLIKFTIITCRKPETTQ
What is the function of this protein?
Involved in the synthesis of tocopherol (vitamin E).  Methylates gamma- and delta-tocopherol to form beta- and alpha-tocopherol, respectively.
What are the official names of this protein?
Probable tocopherol O-methyltransferase, chloroplastic, Gamma-tocopherol methyltransferase, Vitamin E pathway gene 4 protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HSP7L_MIMIV
Sequence: MDNKLNHNDDNTLIQTEDVIGIDLGTRFSCVSIWRNKRFEIIPDQFGNRTIPSVVSFYKSAKLVGHNALCMKDANPKNTIYDIKRIIGRRMNDKSIEQTKNLISYELVSDESKHENILVQLDKSDYTLTHKYQYKPEEICAQILIEIRRIASQYLQKPINKAVITVPAYFNDAQRQATLDSAKIAGLDVLKIINEPTAAALAYGLGSEKWNKKTGGNVIVYDLGAGTLDVSLMNISNGVFRTLAVGGNTHLGGEDFDYLIMNHILIDFRKKHRIKELQMSKLSQLKLKNSVENAKKLLSTVDKAVVCVDDFYNGKQLYFNLTREFMEMVCNELFIMCMKPLKDVLDSSGLTRQDIDKVILVGGSTRIPKIQKLILDFFKNTQINALTMSLNPDEVVSAGASIYGYIITNKGDPFSDNLVLLDITPLSLGVETLQKQMTVIIPRNTVIPTKKTKIFSTDTDDQDNVNIKIFEGERKLTKNNFHVGTFNLSGFEKGPRGYPVIKITFHIDINGILQVTAHEKKSDIQNGIKITSTWGAKGRLSKSDIETIIKEAEQNEEIDKLYSHKIGLVHRINSVCNAITINLKDNEITLTNADKKKIKADIKSNLKWLQNKDINDLEVTELEKRENRLNKLYAPLIIQIGKKSDFKDYNKDTTTAEIHGDDNENDGGIYERIVLESDPSDYEKEEIKALTATIQDLCKNIINVVNNPISKFSREDIDLVTDYMETIQIWTYTTTATSTIEFIAKINEINKFTEDIMKKYEDTKIFEKNDSFTYKDELQLTCLTLNECIKSNYFSVKKSEIDILSKTIKDTMFWLLGHQNEDNSVYKEKLDQVISICNSVYHGMHRIKELENQPDIPEDSEDSESEDDTTTSKDSESSEITENLALPTNKIRENTSELLKRLPDKIKSSTQNKNDVLLKIDLNKLNPNTDIKYKNIDNHYR
What is the function of this protein?
Probable chaperone.
What are the official names of this protein?
Heat shock protein 70 homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS21_XYLFM
Sequence: MPSVKVRENEPFEFALRRFKRICEKAGILAETRKREFYEKPTQERKRKAAAAVKRQMRRTSRDVTKRKRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PDXB_HAHCH
Sequence: MKIVADENIPLLQPFFGSMGEIHTLPGREISNQHLRDADVLLVRSVTKVDERLLENTGVKFVGSATIGCNHVDLDYLTSRGIGFSNAPGCNASAVVEYVVSCLSVLSEQLGFELEDKTVGIIGRGEIGGRLERALTLLGLEVKSNDPPKEAAGEQNLFSLEEVLQCDIITLHTPLTDSGSYPTRELLNATIIENLRPDQILINTCRGEVIDEAALKGRLQKGDGLTVALDVWNNEPAIDVELAMLCHFATPHIAGYTLDGRTAGTEIIYQHLSRYLGLPVRHKLGQFLPEPPLRRMAFSSGVDPDWALHTAIRASYDVRHDDSQLKRTLRLDAPMRAQEFDRLRREYRVRRGFDRIKIELKGGKADLLATLSAVGFNLSSK
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_BURCH
Sequence: MTEPTQTQPAVTADENQIIAERREKLRALREQGVAYPNDFRPEHHAADLQAKFADSDKAALEANPVEVSVAGRMMLKRVMGKASFATVQDGSGQIQFFVTPNDVGADTYDAFKKWDLGDIVAARGVLFRTNKGELSVQCKELRLLSKALRPLPDKFHGLSDQEMRYRQRYVDLIVTPETRDTFRARTKTIASIRKFMDNADFMEVETPMLHPIPGGAAAKPFVTHHNALDMQMFLRIAPELYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEQLIRQAAIDALGTATIQYQGRELDLAKPFHRLTITQAIQKYAPDYTDGQLSDDAFLRTELKRFGVDVSQPAFLNAGIGALQLALFEETAEAQLWEPTFIIDYPVEVSPLARASDTVPGITERFELFMTGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEYGMPPTGGCGIGIDRLVMLLTDSPTIRDVLLFPHLRRED
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMT_PICST
Sequence: MESSLAAIANSGPISIFSYCVSSILMTVTNKYVLSGFSFNMNFLLLAVQSIVCIVTIGSLKSFGVITYRQFNKEEARKWSPIAVLLVIMIYTSSKALQYLSIPVYTIFKNLTIILIAYGEVLWFGGKVTTMALSSFLLMVFSSVVAWYGDEAVSGSGNESFIALYLGYFWMATNCFASAAFVLIMRKRIKLTNFKDFDTMYYNNLLSIPILLASSIIFEDWSAENLAVNFPSDNRTATIAAMVLSGASSVGISYCSAWCVRVTSSTTYSMVGALNKLPIALSGLVFFPAAVNFWSVASIFVGFAAGLVYAVAKQRQQKENVSLPSSK
What is the function of this protein?
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
What are the official names of this protein?
GDP-mannose transporter, GMT.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SGCE_ECOLI
Sequence: MILHPSLASANPLHYGRELTALDNLDFGSLHLDIEDSSFINNITFGMKTVQAVARQTPHPLSFHFMLARPQRWFNALAEIRPAWIFVHAETLDYPSETLTEIRHTGARAGLVFNPATPIDAWRYLASELDGVMVMTSEPDGQGQRFIPSMCEKIQKVRTAFPQTECWADGGITLAAAQQLAAAGAQHMVIGRALFSSSDYRATLAQFATL
What is the function of this protein?
Probable pentose-5-phosphate 3-epimerase.
What are the official names of this protein?
Protein SgcE.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
Protein: YO22B_YEAST
Sequence: MESQQLHQNPHCPHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQEETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQDQHSEVPQAKTKVRNNVLPPHPHTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYSDILTVLCKSVSKMQTNNQELKDWIALANLEYNGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTRTIDSNDELPDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPNIAYDLLSLSELTNQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQNNQTKLDQFDYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSLNPLQLDKEPVQKVRAPKEVDADISEYNILPSTIRSRTPHIINKESTEMGGTIESDTTSPRHSSTFTARNQKRPGSPNDMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSSNSDSTTPIISIETKAACDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTHKSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEKDRYVEAYHKEISQLLKMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGEGDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty2-OR2 Gag-Pol polyprotein, TY2A-TY2B, Transposon Ty2 TYA-TYB polyprotein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y3366_SHESR
Sequence: MEYEFRRNSLTGTYLASFSMDHEVLGQWFSEELGPELAKIQQVLDIIKDIQAGKRDSWRLIGGDLTLDLDEEQARIYANALGFEQEYELEESMSLYDAESEAYCGLEDLEEALLSWYKFVEKGR
What are the official names of this protein?
UPF0231 protein Shewmr7_3366.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: MIAA_MYCBO
Sequence: MRPLAIIGPTGAGKSQLALDVAARLGARVSVEIVNADAMQLYRGMDIGTAKLPVSERRGIPHHQLDVLDVTETATVARYQRAAAADIEAIAARGAVPVVVGGSMLYVQSLLDDWSFPATDPSVRARWERRLAEVGVDRLHAELARRDPAAAAAILPTDARRTVRALEVVELTGQPFAASAPRIGAPRWDTVIVGLDCQTTILDERLARRTDLMFDQGLVEEVRTLLRNGLREGVTASRALGYAQVIAALDAGAGADMMRAAREQTYLGTRRYVRRQRSWFRRDHRVHWLDAGVASSPDRARLVDDAVRLWRHVT
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: EX7S_RALSO
Sequence: MPRAQDVAQSDATLSSPATPASYEAAMAELETLVASMESGELPLEASLAAYRRGAELVRYCQQVLERVEQQVRVLDGDALKPLAGEGTNEQGGA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_XYLF2
Sequence: MTKPIRNVAVLGATGSIGAAALDVLARHPRQFHVSLLAAGQRVDALLALCRTYRPDHAVIGDATLYTTLRDGLNAAGLATKAYAGEAALAELVASTTCDTVVAAIVGAAGLHSTLAAARAGKRLLLANKESLVLAGMLLMREASISGAEIIPIDSEHNAIFQCLRSRTTDGVHRVTLTASGGPFRGHNRTMLAKITPTQAMAHPTWSMGPKISVDSATLMNKGLEVIEAHHLFGLPSEQIDVLVHPQSLVHSLVEFIDGSTLAQLSLPDMRTTLAVGLAWPERIGSGVQGLDLMKHNRLDFEHPDTETFSCLRLARDAMQTGGTAPAVLNAANEIAVSAFLQGRIGFLTIPALIEHALTTLPRYEADTLETLLTVDTETRRITHAALTHFPLPL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RS7_CHLCH
Sequence: MSKLRSYKKIGGDYRYGDESVARFINAVMLDGKKAVATKIVYDAFSIISERNNGEDALEIYRKAISNIAPVVEVRSKRVGGATYQIPMEVKPSRRSALAFRWLKIYAGKRGGKSMAEKLAAELMDAANDQGASVKKRDEVHRMAEANKAFAHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: IREB2_RAT
Sequence: MDSPSAGYTFEYLIETLNGSSQKKFFNVPKLGGTKYDILPYSIRVLLEAAVRNCDGFLMKKEDVINILDWKTKQSNVEVPFFPARVVLQDFTGIPAMVDFAAMREAVKTLGGDPKKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDSGELSRNSGTFSSQIENTPVLCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSGAFKNVAVIPPGTGMAHQVNLEHLSRVVFEEADLLFPDSVIGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVTLTLPEVVGCELTGSSNAFVTSIDIVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLRHLEHTGFDKTKLESMEEYLKAVKLFRNDENSSEPEYSQVIQINLNSIVASVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQVAAEKQSDTVSVRYDGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVETGLRVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSEAILNAVKQGDLVTCGVLSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKNIYLHDIWPSREEVHQIEEEHVILSMFKALKEKVEMGNKRWNSLDAPDSVLFPWDVKSTYIRCPSFFDKLTKEPAASQPIENAHVLLYLGDSVTTDHISPAGSIARSSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLEFLPGENADSLGLSGREVFSLSFPEELFPGITLNIKTSTGKEFSVIAAFENDVEITLYKHGGLLNFVARKFL
What is the function of this protein?
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA.  Binding to the IRE element in ferritin results in the repression of its mRNA translation.  Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
What are the official names of this protein?
Iron-responsive element-binding protein 2, IRE-BP 2, Iron regulatory protein 2, IRP2.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYLK3_DANRE
Sequence: MGTSLYRSTLLSTGGFSVSDYIRKFTKNKPDVNNIQPNVGFCHQSTQTSQQVKEVISAELELQQPEVTLPNDPSSQHSPEAHTGASEPLKPVSAGESSKALQKAKEISVKSSEPTHVQTFAPAVHLEQIDVHNVPKQETNSLVAAPADAKCVIETMTKVEKDIALQQERALERADDSHVANKVFLKSIIPGQQLEKIEDPQQQAEVSLFVDEDSLEKSVPGQHLDKKMEVLQKQAKDLPVVDEDSLNLSAPGQRQLEEKVDVPEKAEKKIDEAHKKMEEVPRKDELCIEKPVIRHAGIKTQHEETMGMETTVPKHDESKCPTETYVEKTENKNADVTLESDKIMICAVSPQNTSLDEDEKSKAAPLRKVESTLLIIDDSPPLPAPFDHRIVSAKQVPINSYYAVNPVEVLGGGRFGQVHKCAELSSGLTLAAKIIKVRGMKERDEVKNEIGVMNQLNHVNLIQLYDAFESRTNLTLIMEYVEGGELFERIIDESYQLTELDAIVFTRQICEGVQYLHQQYILHLDLKPENILCVNSTGNQIKIIDFGLARKYRPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVITYMLLSGLSPFMGDNDAETMNNILHAKWEFDTEAFENVSEEAKDFISSLLVSAKCSRLSASGCMKHSWLNNLEDKAKMYKVRLKSQMMLQRYLVAHRQWKKHFYAVAAANRLKRFQQSRSISTPN
What is the function of this protein?
Kinase that phosphorylates MYL2 in vitro (By similarity).  Increases cardiomyocyte contractility (By similarity).  Required for sarcomere formation in the developing heart.
What are the official names of this protein?
Myosin light chain kinase 3, Cardiac-MyBP-C-associated Ca/CaM kinase, Cardiac-MLCK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEA6_ECOLX
Sequence: MSGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGPFKFGLWGVALYGVLPSQIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPAVQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKSDADAALSSAMESRKKKEDKKRSAENKLNEEKNKPRKGVKDYGHDYHPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKGRKIYEWDSQHGELEGYRASDGQHLGSFEPKTGNQLKGPDPKRNIKKYL
What is the function of this protein?
Colicins are polypeptide toxins produced by and active against E. coli and closely related bacteria.
What are the official names of this protein?
Colicin-E6, Ribonuclease.
What is the protein family that this protein belongs to?
Belongs to the cloacin colicin family.
Protein: RL7_ENT38
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPAEAAEEKTEFDVILKGIGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKSLEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: MRAY_STRP3
Sequence: MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFLKIFKQINEGLTAKQKLALQLAGGLMFYFLHVSPSGISSINVFGYQLSLGIFYLFFVLFWVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFCFNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKYTKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILYVF
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KGUA_RHOPS
Sequence: MKDGSGGFNGVERRGLMFVLSSPSGAGKTTLSRMLVDEAPGLTMSVSATTRPRRPGEVDGRDYYFVDRPKFDAMVEADEFLEWAHVFDNCYGTPRAPVEAALAAGRDVLFDIDWQGTQQLRSRASNDVVSVFILPPSVQDLEHRLHTRAQDSDEVIRGRMKKAGDEMSHFDAYDYIVVNDNIGVAFESVKAILRAEQLKRERQIGIEAFVRDMRRQLEK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.