PharMolix/UniProtQA huggingface dataset:
Protein: KCRU_RAT
Sequence: MAGPFSRLLSARPGLKLLALAGAGSLAAGILLRPESVRAATGERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFAELFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKKVEKLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVKLPLLSKDSRFPKILENLRLQKRGTGGVDTPATADVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLEKGQDIRIPPPLVHGKH
What is the function of this protein?
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e. g.  creatine phosphate).  Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
What are the official names of this protein?
Creatine kinase U-type, mitochondrial, Acidic-type mitochondrial creatine kinase, Mia-CK, Ubiquitous mitochondrial creatine kinase, U-MtCK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: RL30_STAAT
Sequence: MAKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNPAIRGQINKVKHLVTVEEK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RR7_POPTR
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQILYRAMKKIQQKTETNPLSVLHQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMVFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NDHK_POPAL
Sequence: MNSIEFPLLDRTTPISVISTTSNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEQKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAIIDAITKLRKKISREIYEDRIRSQQGNRCFTTNHKFHIGRTTNTGNYDQGLLYQPPSTSKIAPEAFFKYKKSVSSSELVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: FPR3_PONPY
Sequence: METNFSIPLNESEEVLPEPAGHTVLWIFSLLVHGVTFIFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGTFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMMGLWILAIVLTLPNFIFWTTISTKNGDTYCIFNFPFWGDTAVERLNAFITMGKVFLILHFIIGFSMPMSIITVCYGIIAAKIHRNHMIKSSSPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLLNPTSSLAFFNSCLNPILYVFLGSNFQERLIRSLPTSLERALTEVPDSAQTSNTHTNSASPPEETE
What is the function of this protein?
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors.  Binding of FMLP to the receptor causes activation of neutrophils.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
N-formyl peptide receptor 3, FMLP-related receptor II, FMLP-R-II, Formyl peptide receptor-like 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LGT_THEP1
Sequence: MKKILAFLSIAAGSTLFFVFLFIFLSKVFSGEILLSRYIFRIGGFELRWYSTLILTGFLISYFVARKRAKNEGINLEEFDELIFYGVIAGIVGARLYYVLFNLKYYRSLWDALKIWEGGLAIHGAVIGALLTGFLYVRLKKPSFTFLQATDLFTSVLPLGQAIGRWGNFFNYEAFGVPTNLPWKMFVPEPYRPVVYKDYSFFHPTFLYESIWDLLVFFMLSVYFKRYRKRHGEVTCLYFVLYSLGRIVIERLRVDSLMIGNIKAAQLLSAVLILLGFTGFLILRSSQEPKRAF
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: E2AK2_SCHPO
Sequence: MRFFNAHKSAEDGNYSETTNAISLKNERQSRDLSVNKHGRMLLTALLENFCQLYDNNPAKSKRLFALICHTLQKIGILEEEYIEELAAVRSNYQDALHHLILQAREAIRLDDAEERLLALPDPTNVFEKFPQETALSKFSVDGLNVRQFRFRDLTLESWLQSRNSRYIEDFEEYSLLGRGGFGSVYHVRNKIDGAEYAMKKINSTFQQMSYSKIFREIKCLAKMDHPNVIRYFSSWVESTTEATQMPIVMSKNSSRVLGTSSYCDVNGMDSIIFEPTESSALTDDILFAEDPGTESIISTSRKSSYSSTTESSNFENLESPRNLHDSNVSTFNNTTILDDDYSSSMHISKTGPTHSFIIYIQMQLCFDDLESYLIRRNHFLSFPLCKEQIQLHTDLFRMIINGVMYVHEGVNLIHRDIKPSNIFLAKSLPEDRGSVPLISYNDKNDLKEYITPKIGDFGLVVENKKNTETALSFLERNHLPNLQDETQHIGTATYAAPELLDAMSSQHNKFTKKIDTFSLGMVLFELLHPFQTNMERATKLQDLRRGNLPEEFVEQHICESSLILWMTAKDPTKRPSLLEVLNCGLLLPNQVSMPNISNIVSTNHLDVETQMKLIMDENQRLREQIAVLRSRIQHLETR
What is the function of this protein?
Mediates down-regulation of protein synthesis in response to stress conditions by the phosphorylation of the alpha subunit of eIF-2 (tif211) on 'Ser-52'.  Protein synthesis is inhibited at the level of initiation.  Activity is inhibited in the presence of heme.
What are the official names of this protein?
Eukaryotic translation initiation factor 2-alpha kinase 2, Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase, Heme-regulated inhibitor 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
Protein: LOLA_SALPB
Sequence: MKKMAIACALLSSVVASSVWADAASSLKSRLDKVSSFHATFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQASDWQQYNIKQDGDNFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSAYQLKSQQNGAVDPSKFTFTPPQGVTIDDQRK
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MOT7_MOUSE
Sequence: MRASGQGPQRRRRGWATRDDSAVTFRDPQPRQPAGGARALRGPDPRGPARAHQAGPLLAGARRSQHMVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGGWGWAVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNSKISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASFSQRVYHMYISIGVISGLGYCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKEHIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSPKAVTLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKMEQETRAEQQQTLVTAPKHSQMKAPLLDFSVLKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDPDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTASLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMCLAAVCLALVRPCKKGLCQNSHSGENQTDRQRGKALQDIPEDFLEMDLGKCEHRAHMKMDPV
What is the function of this protein?
Proton-linked monocarboxylate transporter.  Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
What are the official names of this protein?
Monocarboxylate transporter 7, MCT 7, Monocarboxylate transporter 6, MCT 6, Solute carrier family 16 member 6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMH_CHLAD
Sequence: MVVTFQHVPVMVAEVVAALAPRPGGRYIDATVGGGGHALAVLQAARPGGRLLGIDADPAALVATADRLAEAGLREHAVLCHGSFADLAVIAGETGFINVDGILFDLGVSSYQLDTPERGFSFAADGPLDMRLDPTQGPTAADLVNTLSERELADVIFQYGEEHAARRIARAIVERRRTQPFQRTADLAAVIARVVGGRRGRIHPATRTFQALRIAVNRELDRLAAALPQAVHLLAPGGRLVVISFHSLEDRIVKQFMRAEAEGATPRLVINTKKPVAATDDEVATNPRARSAKLRVATRIV
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRS4_KLULA
Sequence: MRFRSRHQVDKPNVIVTQSNRKNEDRLGEDASLKAAQAMFKKHTVSQGFAVSDAPGTKLSLPNSGHGTPAHNVQAMARSSSSSSATSTPINIIRRSPRSSLKGKPMGGLSVSPRTVEGNAALSQQAAAVALENEISGDESIVLVPAGNSNGSMTRSNSSINAIRIVPGGGLSSSRSSSKVSIVKNSPTHSLALADKLNSITLESVYGKPSTATGTATRTLAGRKAPPAAFIDQDSVLSNDKHSENEDTPIKGTISYDTTARMNVPVTYEGTLPDLIPGHQRHKKKKWRNIFGSSATHGSSAGGAIGINGTSASGNDQYENPSGTLSELQLNRAEDNLIVKSVNPTQKTRLQTTLRSNDYDRNSELAAVAGGYSSDESAFSSDSDRELHYATDNHHNNSINNHSSGVYYGNVGGNGVYNGGTAGVGRTKHRAMVRSHKRKSFNEDKPWKSHVDIGYISERERKRYEGIWVTNRNSYLELLPWWNQPLQDEEQEQEQEREMDHESQHGLEEELEEEREQESGQGQEQDADIPEDGLMLNLIVMEIWSRSNLSNQLLGQIYDKVDTRHDGTLNRQSFLTGMWLVDQCLYGRKLPKQIDQRVWDSVDKFVISIPNNNPHHRHRRRKKMLRKELKTIKKDLKT
What is the function of this protein?
Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway.  Involved in rDNA silencing (By similarity).
What are the official names of this protein?
Increased rDNA silencing protein 4.
What is the protein family that this protein belongs to?
Belongs to the IRS4 family.
Protein: EPT1_HUMAN
Sequence: MAGYEYVSPEQLAGFDKYKYSAVDTNPLSLYVMHPFWNTIVKVFPTWLAPNLITFSGFLLVVFNFLLMAYFDPDFYASAPGHKHVPDWVWIVVGILNFVAYTLDGVDGKQARRTNSSTPLGELFDHGLDSWSCVYFVVTVYSIFGRGSTGVSVFVLYLLLWVVLFSFILSHWEKYNTGILFLPWGYDISQVTISFVYIVTAVVGVEAWYEPFLFNFLYRDLFTAMIIGCALCVTLPMSLLNFFRSYKNNTLKLNSVYEAMVPLFSPCLLFILSTAWILWSPSDILELHPRVFYFMVGTAFANSTCQLIVCQMSSTRCPTLNWLLVPLFLVVLVVNLGVASYVESILLYTLTTAFTLAHIHYGVRVVKQLSSHFQIYPFSLRKPNSDULGMEEKNIGL
What is the function of this protein?
Ethanolaminephosphotransferase that catalyzes the transfer of phosphoethanolamine/PE from CDP-ethanolamine to lipid acceptors, the final step in the synthesis of PE via the 'Kennedy' pathway (PubMed:17132865, PubMed:28052917, PubMed:29500230).  PE is the second most abundant phospholipid of membranes in mammals and is involved in various membrane-related cellular processes (PubMed:17132865).  The enzyme is critical for the synthesis of several PE species and could also catalyze the synthesis of ether-linked phospholipids like plasmanyl- and plasmenyl-PE which could explain it is required for proper myelination and neurodevelopment (PubMed:29500230).
What are the official names of this protein?
Ethanolaminephosphotransferase 1, hEPT1, Selenoprotein I, SelI.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PSTB_MYCSM
Sequence: MAKRLDLKDVNIYYGAFHAVADVSLAVQPRSVTAFIGPSGCGKSTVLRTLNRMHEVIPGARVEGSVLLDGEDIYGPGVDPVGVRKTIGMVFQRPNPFPTMSIRDNVVAGLKLQGVRNKKTLDEVAERSLRGANLWNEVKDRLDKPGGGLSGGQQQRLCIARAIAVQPDVLLMDEPCSALDPISTLAIEDLIATLKLDYTIVIVTHNMQQAARVSDQTAFFNLEATGKPGRLIEIDDTEKIFSNPRQKATEDYISGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL21_AERHH
Sequence: MYAVFQSGGKQHRVAEGQIVRLEKLNVETGATIDFNEVLMVAAGDTFKVGAPFVEGGKVVAEVVAHGRGEKVTIVKFRRRKHHRKQAGHRQWFTEVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GREA_STAES
Sequence: MENQKQYPMTQEGYEKLEQELEELKTVKRPEVVEKIKVARSFGDLSENSEYDAAKDEQGFIEQDIQRIEHMIRNALIIEDNGDNNVVQIGKTVTFIELPGDEEESYQIVGSAEADAFKGKISNESPMAKALIGKGLNDQVRVPLPNGGEMNVKIVEIK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: LEPA_JANSC
Sequence: MTDLNRIRNFSIVAHIDHGKSTLADRLIQLTGTVAARDMQAQLLDQMDIERERGITIKANTVRIEYPAKDGHTYILNLIDTPGHVDFAYEVSRSMQAVEGSLLVVDASQGVEAQTLANVYQAIDADHEIVPVLNKVDLPAAEPDRVREQIEDVIGIDASEAVEISAKTGIGIPDVLEAIVTRLPAPKGDRDAPLKAMLVDSYYDSYLGVVVLIRVIDGVIKKGDKIKMMRTGGQYPVDRLGVFTPKMKDIGELGPGEMGFLTASIKQVRDTRVGDTITHDKHGAEQPLAGFKPSQPVVFCGLFPVDTNQFEDLRDAIEKLALNDASFSHEMETSAALGFGFRCGFLGLLHLEVIRDRLEREYDIDLITTAPSVIYHVHMRDETMVDLHNPADMPDPAAIDRIEEPRIKATILVPDDYLGDVLKLCQDRRGIQIDLTYAGTRAMVVYDLPLNEVVFDFYDRLKSVTKGYASFDYQMIGYREDALVKMQVLVNDEPVDALSIMVHRDRAETRGRAMVEKLKDLIPRHMFKIPIQAAIGGRVIARETLSAMRKDVTAKCYGGDASRKRKLLDKQKAGKKKMRQFGKVEIPQSAFISALKMDG
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ABCB7_RAT
Sequence: MALLAIHSWRWAAAAVAFEKHKHSAVLTRSLVSICGSGLRWSSYQSGASGSARLSQTTESLRNSTQQRWEKNNSRQLLDASKVLQAWPLIEKRTCWHGHAGGGLHTDPKEGLKDVDTRKIIKAMLSYVWPKDRPDLRARVAISLGFLGGAKAMNIVVPFMFKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIVFEMTLVSSVLYYKCGAQFALVTLGTLGAYTAFTVAVTRWRTRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNEKYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGIVAGALTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTRIKDKAMASPLQITPQTATVAFDNVHFEYIEGQKVLSGVSFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNINASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMRDVVKHRTSIFIAHRLSTVVDADEIIVLSQGKVAERGTHYGLLANSSSIYSEMWHTQSTRIQNHDNLGWDAKKESLSKEEERKKLQEEIVNSVKGCGNCSC
What is the function of this protein?
Exports glutathione-coordinated iron-sulfur clusters such as [2Fe-2S]-(GS)4 cluster from the mitochondria to the cytosol in an ATP-dependent manner allowing the assembly of the cytosolic iron-sulfur (Fe/S) cluster-containing proteins and participates in iron homeostasis (By similarity).  Moreover, through a functional complex formed of ABCB7, FECH and ABCB10, also plays a role in the cellular iron homeostasis, mitochondrial function and heme biosynthesis (By similarity).  In cardiomyocytes, regulates cellular iron homeostasis and cellular reactive oxygen species (ROS) levels through its interaction with COX4I1 (PubMed:31511561).  May also play a role in hematopoiesis (By similarity).
What are the official names of this protein?
Iron-sulfur clusters transporter ABCB7, mitochondrial, ATP-binding cassette sub-family B member 7, mitochondrial, ATP-binding cassette transporter 7, ABC transporter 7 protein.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS4_NITWN
Sequence: METVILFPAIDLKSGQCVRLEQGDMARATVFNLDPVEQARAFAAQGFEYLHVVDLDGAFAGKPVNADAVERVLRNVALPMQLGGGIRDLKTVEAWLGKGVARVIIGTAAVRDPVLVREAAKAFPGRVAVGLDARDGKVAVEGWAETSEVTALDIARRFEDAGIAAIIFTDIARDGLLKGLNLDATIALADSISIPVIASGGFASIADVKALLEPRAKKLAGAISGRALYDGRLDPVEALKLIHAARAAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_BURP6
Sequence: MTQWEVVIGLETHAQLSTVSKIFSGASTQFGAQPNTQACPVDLALPGVLPVLNRGAVERAIRFGLAIGATVAPRSVFARKNYFYPDLPKGYQISQYEIPVVQGGQITIQVPANEKAGKQAYSKTVNLTRAHLEEDAGKSLHEDFAGMTGIDLNRAGTPLLEIVTEPEMRSAAEAVAYAKALHGLVMWLGICDGNMQEGSFRCDANVSVRPVGQEKFGTRAEIKNLNSFRFLEDAINYEVRRQIELIEDGGEVVQETRLYDPDKRETRSMRSKEDAHDYRYFPDPDLMPLVIGADWIARVKGEMPELPAAMQQRFVEQYGVSAYDAGVLTSTKAMAEYFEALVAKAGAANAKLAANWLMGDVSSQLNRDGIDIDACPVSAAQLALVLQRIADGTISNKIAKEIFVTIWDEKAADEGAADRIIEAKGLKQISDTGALEAIIDEVLAANAKSVEEFRAGKDKAFNALVGQAMKATKGKANPQQVNELLKKKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: Z_CHAVB
Sequence: MGNTKTKDRQYQSNSSQPTNTSAPVLLRRQAEPSLYGRHNCRCCWFADTNLVNCSNHYLCLKCLNTMLRRSNLCDICGEELPTTIIVPVEPSAPLPGQ
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L.  Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z.  Also selectively represses protein production by associating with host eIF4E.
What are the official names of this protein?
RING finger protein Z, Protein Z, Zinc-binding protein.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae Z protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Mainly perinuclear. During budding, associates at the inner side of the plasma membrane of infected cells.
Protein: BP10_PARLI
Sequence: MKLILFLSGLVSLVLCTLAAPTGDQKEIHTETPPPKKPSETTTPGALKTPQPEPKDEEPTPGAFQGDMMLTEDQQRESKEAIDDEMTGRKKRKATIYESQRWPYKVIPYVISPSSSGQSSLIRNAMDHWEQNTCLRFEPRTSSHSRQLGHNAYLSFFRGSGCWSYVGKAFNGEQQISIGNGCAYFGTIVHEIGHAIGFHHEQSRPDRDDYINVLYQNIQSGRQHNFAKYTWGRVTSRNVEYDVGSIMHYGGYGFSSNGRPTITTRDPRLNSRLGQRIALSPADIELANLIYECDDIEDCAGANECLNGGYHDTECNCVCPSGYNGDLCEDAVTTTRPDCSERFTEMTGVITSPNWPGRYEDNMACVYQIEGPPGSTIELTFTEMNIENHAACRYDAVEVRKDDINSDGEKFCGNTLPAVQISSGNQMLISFTSDPSITGRGFRATYRIVILTTTQIPDTTTISTTTPVPTTTQATTDETVVGSCGGSFGGTQGRVATPNYPNNYDNDLECVYVIEVEIGRRVELDFIDFVLEDETNCRWDSLSINLGDGIKIDMKMCGREYPAASLVSIGNNMELTLISDRSVTDRGFMADYRAIDL
What is the function of this protein?
Could be involved in the differentiation of ectodermal lineages and subsequent patterning of the embryo.
What are the official names of this protein?
Blastula protease 10.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm, cell cortex. Secreted, extracellular space. Note=First detected in a perinuclear region, then in an apical and submembranous position just before its secretion into the perivitelline space.
Protein: RR7_GUNCH
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAMKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANXAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRI_META3
Sequence: MNHLGDIMKNSLKVEPIENGTVIDHIKQGKALNVYNALDIKKDKTITIAMNVPSGKNHKKDILKIEGIELSKYDVDKISLISPNATINIIKNKIVINKFKVEIPNTIEGILKCTNPNCITNIENVAGKFDVEGREPLKIRCFYCEKFLNSIEVYK
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.