PharMolix/UniProtQA huggingface dataset:
Protein: AROA_RHIME
Sequence: MSHGSNPRPATARKSSDLKGTLRIPGDKSISHRSFMFGGLAAGETRITGLLEGEDVINTGKAMQAMGARIRKEGDTWIIDGVGNGALLAPEAPLDFGNAGTGCRLTMGLVGVYDFDSTFIGDASLTKRPMGRVLDPLREMGVQVKSAEGDRLPVTLRGPKTPNPITYRVPMASAQVKSAVLLAGLNTPGITTVVEPVMTRDHTEKMLQGFGANLTVETDAEGVRTIRLEGRGKLTGQVIDVPGDPSSTAFPLVAGLIVPGSDITILNVLMNPTRTGLILTLQEMGANIEVMNKRLAGGEDVADLRVRHSELKGVTVPEDRAPSMIDEYPVLAVAAAFAEGTTVMNGLEELRVKESDRLSAVADGLKLNGVDCDEGEASLVVRGRPGGKGLGKISGGQVKTHLDHRIAMSFLVMGLASEHPVTVDDATMIATSFPEFMGLMTGLGAKIEEAENKAA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNB_SYNP6
Sequence: MKKIEAIIRPFKLDEVKIALVNAGIVGMTVSEVRGFGRQKGQTERYRGSEYTVEFLQKLKLEIVVEDAQVDTVIDKIVAAARTGEIGDGKIFVSPVDQTIRIRTGEKNADAI
What is the function of this protein?
P-II indirectly controls the transcription of the GS gene (glnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA.  When P-II is phosphorylated, these events are reversed.  In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is phosphorylated which allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme.
What are the official names of this protein?
Nitrogen regulatory protein P-II, PII signal transducing protein.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: ATP6_CERS4
Sequence: METEVEHTGLAIHPMDQFIVKKLFCHTESTAPMNECTTNIHWYDITNVTMWMAIAVLVIAAILVLGTRRRAIVPSRSQSVAELLYGFIHNMVEEVTGHEGVKYFPYVMTLFLFVLCGNVLGLLPLSFTTTSHMAVTVPLALMVFVGVTALGFMKNGPGFLKMFWVTSAPLAIRPVLAVIEVISYFVRPVSHSIRLAGNMMAGHAVIKVIAGFASIVVVSPVVVGAVTAIYALELLVAVVQAYVFTILTCVYLRDAVGDAHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TIKI2_MOUSE
Sequence: MHAALAGPLLAALLATARARPQPPDGGQCRPPGSQRDLNSFLWTIRRHPPAYLFGTIHVPYTRVWDFIPDNSKAAFQASTHVYFELDLTDPYTISALASCQLLPHGENLQDVLPRELYWRLKRHLDYVKLMIPSWMTPAQRGKGLYADYLFNAIAGNWERKRPVWVMLMVNSLTETDVRSRGVPVLDLYLAQQAEKMKKSTGAVERVEEQCHPLNGLNFSQVLFALNQTLLQHESVRAGSLQAPYTTEDLIKHYNCGDLNAVIFNHDTSQLPNFINTTLPPHEQVTAQEIDSYFRQELIYKRNERMGKRVMALLQENQDKICFFAFGAGHFLGNNTVIDVLRQAGLEVDHTPAGQAIHGPAAVGSPAPPPEITSPASPAPATPAAAVPEATSATPTTPPEEEDPVLSPHLLLPDSLSQLEEFGRQKWRKRLNKHQRPRQFNDLWVRIEDSTTISPPPLPLQPTPSSETTKPFVKSSHQLQQQDAVGPTSSSAPTLGLLHAITASIVAPFLLHSLGPS
What is the function of this protein?
Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins.  Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.  Able to cleave WNT3A, WNT5, but not WNT11.  Required for head formation (By similarity).
What are the official names of this protein?
Metalloprotease TIKI2, Heart, kidney and adipose-enriched transmembrane protein, TRAB domain-containing protein 2B.
What is the protein family that this protein belongs to?
Belongs to the TIKI family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MSHR_HYLME
Sequence: MAVQGFQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSIPDGLFLSLGLVSLVENVLVVATIAKNRNLHSPTYCFICCLALSDLLVSGGNVLETVVILLLEASALAARAAVVQPLDNVIDVITCSSMVSSLCFLGAIAVDRYVSIFYALRYHSIVTLPRARQAIAAIWVASVLFSTLFIAYYDHAAVLLCLVVFFLAMLVXMAVLYVHMLARACQHAQGIARLHKRQRPLHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPQHPTCSCIFKNFNLFLTLIICNAIIDPLIYAFRRQELRRTLKEGLTCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL21_RHILW
Sequence: MFAVIKTGGKQYRVAANDVLTIEKLEATAGDSIEFTEVLVIGEGADAAIGAPFVTGASVKAEVVEQNRGKKVIAFKKRRRQNSKRSRGHRQHHTVVRITDIVAAK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: YCIZ_SHIFL
Sequence: MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVAESTPDIPKTPWEI
What are the official names of this protein?
UPF0509 protein YciZ.
What is the protein family that this protein belongs to?
Belongs to the UPF0509 family.
Protein: RL34_HELPY
Sequence: MKRTYQPHNTPRKRTHGFLVRMKTKNGRKVINARRAKGRKKLSV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: XERS_LACLA
Sequence: MKREQLIQNIEKLKHIMPSYVLEYYQSKLTIPYSLNTLYEYLKEYERFFSWLVDSGVADVDKITDVSLSVLENLTKRDLESFILYLRERPRLNTRSTRYGVSQTTINRTLSALSSLYKYLTEEVENEDGEPYFYRNVMKKVQTKKKSETLASRAENIKGKLFLGDETQGFLDYIDNEYEKTLSNRARSSFFKNKERDLAIIALILASGIRLSEAVNVDLRDLNLITMVVEVTRKGGKRDAVPYAPFAKTYFERYLEVRSQRYKTTAKDTAFFVTLYRDVPSRIDPSSVEKLVAKYSQAFKVRVTPHKLRHTLATRLYAQTNSQVLVSNQLGHASTQVTDLYTHIINEEQKNALDNL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHF_PSEPU
Sequence: MQVKRFFAADMRQAMKLVRDELGADAAIIGNRRIAGGVELTAALDYKLSALAPRVPNAELEEELRKTHTRIATAQAELDHRQDSSDNNRQLFAGQSLTAAEPLIEPHVDAPEAAAAPAPAAAPVDPRLFDAMRSELSGLRELLEVQLGSLAWSQLQGSKPQQANLWRRLQRIGLSGPIARELLDLTAEIEEPRQAWRMLLAHLARMIDIPEIEPIEEGGVIAMVGPAGMGKTTTLAKLAARYVLKYGAQNLALVSMDSFRIGAQEQLKTLGRILNVPVTYVDPGQSLAAALEPLLRKRVVLIDTAGLQASDPALRMQLETLAGRGIAAKNYLVLATTSQKQVLTAAYHSYKRCGLAGCILTKLDETASLGDVLSLAISHELPVAYLTDGPRIPDDLHLPRGHQLVSRAVNVQQQDEPSEEAMADMFADLYHNPRRAG
What is the function of this protein?
Necessary for flagellar biosynthesis.  May be involved in translocation of the flagellum (By similarity).
What are the official names of this protein?
Flagellar biosynthesis protein FlhF, Flagella-associated GTP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ORD_DROME
Sequence: MYGETTLNKNHVIKFIKLKINNCLGCDEVEINFSKADNVHIIIYSLVTDMAKDLPAVTPVAQAILLLCSLTYPDSDSLETIPQLKIGKGSVSMSFKVYPVNKEEETEPESESDLDEGPSTSKQALERMVQRAERKAKEASTRNVHSKGIYVNVERRFDMYFALDTVSYYINGGKRQSCPLPEFHAKFFVRPQHSINLLRQLHEKCSGNWLKVIQSDGDGDAFKKFKDPDSPFETFVKLFESNPIKPNDMMGKLAKTCLHVNEAVRLTEREFILEVFNQVRHIFEYITAQEYTVWFLVPCLGDKDQLRSKTLEDFDLTKVRTSIRRAGDTSNIWWDHTDHNIKDILLVAFQLDLATHVNQSVLVISHLETLAEFSTMQYVTAFFMNDFYAKKNTEPKWICHRYLERIIDVALFLGVIVIIEYPSAFTLLQEGRHLIKCFQKENADSSRTSQWEIFEDVVKENESDLEFLKEAVGKVQQNV
What is the function of this protein?
Essential for proper maintenance of sister-chromatid cohesion in both male and female meiosis.  Mutations in ord cause premature separation of the sister chromatids in meiosis I and random segregation in both meiotic divisions.  Required for chiasma maintenance in female meiosis.  Mutations in ord reduce recombination in female meiosis.
What are the official names of this protein?
Protein ORD, Orientation disrupter protein.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=In male meiosis it assembles onto chromosomes in late G2 of the meiotic cell cycle. It remains at the centromeres after chromosome condensation, through the meiosis I division until the separation of sister chromatids at anaphase II.
Protein: HUTU_SPHAL
Sequence: MTRLDNSRVIRPATGPEISAKSWLTEAPMRMLMNNLHPDVAEAPHELVVYGGIGRAARDWESYDRIVETLRRLEGDETLLIQSGKPVGVFRTHADAPRVLLANSNLVPQWANWEHFHELDKKGLMMYGQMTAGSWIYIGSQGIVQGTYETFVEMGRQHYGGDLSGRWLLTAGLGGMGGAQPLAAVMAGASCLAIECQPSRIEMRLRTGYLDRQAASIDEALAMIEASHAEDKPVSVGLLGNAAEILPEIVRRGIRPDLLTDQTSAHDPVNGYLPAGWSLDQWFAKRESDPSAVAKAAKASMAVHVRAMLDLHAAGVPTTDYGNNIRQMAKDEGVENAFDFPGFVPAYVRPLFCRGIGPFRWVALSGDPEDIYRTDARVKQLLPDNTHLHNWLDMARERIQFQGLPARICWVGLGDRHRLGLAFNEMVASGELKAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGYSQHSGMVIVADGTPEAAKRLERVLWNDPGTGVMRHADAGYDIAIDCAREKGLDLPSI
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUKB_ECOK1
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSHHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRKQLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEFLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLNQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: FABH1_BACAN
Sequence: MNVGILGIGRYVPEKVVTNHDLEKIMDTSDEWIRTRTGIAERRIADDTIDTSYMAVEASKKALEDAGISGEDIDLILVATVTPDRAFPAVACVIQEAIGAKHAAAMDLSAACAGFMYGMITAQQFIQTGTYKNVLVVGSDKLSKIVDWNDRNTAVLFGDGAGAIVMGAVSEGKGVLSFELGADGSGGKHLYQDEYVMMNGREVFKFAVRQLGDSCLRVLDKAGLTKEDVDFLVPHQANIRIMESARERLNLPQEKMSMTIEKFGNTSASSIPIAMVEELQNGRIQDGDLIILVGFGGGLTWGAVALRWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III 1, Beta-ketoacyl-ACP synthase III 1, KAS III 1, 3-oxoacyl-[acyl-carrier-protein] synthase 3 1, 3-oxoacyl-[acyl-carrier-protein] synthase III 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMG_ALCBS
Sequence: MTPFHHPWGELCLQRWPRRRNETLQAWDNADLYLLNTLAERGQALGNGDNAPKTLVLNDQQGALCLALQQAAASALDIESSGDSYTAAAAARANAVDNGLDPNLLFCWPLDAPKQSPDQVIMRVPKSIALLQWQLQWLSGHLPKGVPIWLAGMDKHLPRQLVPLMQRYLGNGRAEYGWKKARLFSAQAPGRVLADTDYPCRVDALQWRLTVHAGVFAQQQLDIGARFFLDHLPEALHTGAKVADLGCGNGVIGMAVLKANPAARVTFCDESWLALESARDNVSRYFSDAESHFHLGDGLAGLEQRFDCILLNPPFHDGYVVGDHVARRLFNQAATALVPGGELRVIGNRHLGYHKVLARRFTSVTVLASNAKFVVWRCQGPTPSASNPLD
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCW1_ASHGO
Sequence: MLAVTFTAAAVLSLLAASGRTLNLDVDDLQSIREATSLLATGLMDYYHGHDYGETVGKFSDPYYWWEAGGAWGSILDYWYYMENSTYNDLLTDSLLHQAGEDLSYTPWNETTTEGNDDQFFWGMAVMAAAERNFPNPPADQPQWLALAQAVFNTMALRWDMETCNGGLRWQIFRWNDGYHYKNSVSNGALFHMAARLTRYTGNATYLEWAERVYDWMYGVGLISIVQPNWHVVYDGTDINDNCTNLNKLQWTYNHGLIMAGCAFIYNHTQDELWHQRTLRFLDSARIFLSNDTLYEAGCQGGDNCNIDQRSFKAYFSRFLGLTAQLVPESRETIVRWIRASAQGAAASCSGGRDGHTCGLNWLINGWDGKWGLGEQMAALEIIQNLRCLERPAPYTAMNGGTSPGDPAAGTKTKAENLPPLDIKAGDRAGAGIITALIGSSFLACTLWLII
What is the function of this protein?
Required for normal synthesis of the cell wall.
What are the official names of this protein?
Mannan endo-1,6-alpha-mannosidase DCW1, Defective cell wall 1, Endo-alpha-1->6-D-mannanase DCW1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 76 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell membrane; Lipid-anchor, GPI-anchor.
Protein: ACCD_SYNS3
Sequence: MSLFDWFADRRKGQYVGKVNQEPDEGDGLWSKCPECGQVVYRKDLLSNASVCGNCGYHHRIDSTERIAVLVDPNSFVPMDQELQPTDPLGFKDRRAYADRLRETQASTGLRDGVITGLCEVEGIPMALAVMDFRFMGGSMGSVVGEKITRLVEVATAKKLPLLIVCASGGARMQEGMLSLMQMAKISGALERHREAGVLYMPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIEQTLREKLPDNFQTAEYLQEHGFVDSIVPRTQLRSTLASLLRLHGCESRVASS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJE9_YEAST
Sequence: MKVDLPESRLPSLYRDFRPLKDLNPDGYEANISTWRDFFLQQYISNSNRIIFTIGTRTLQELTHEVYGVPKSIDIAIDVLVNEGNLIPMELFNLGGMYTDNSRKGFWKWVRSWKESTNMYKSRKDETNFYLREDKFIIKANLEKEYQRFHELLKRSVFMEASSITDLVFTRNEFVTTESLQSFFSTYDEETKNVFLHFIENYKHIIVSKDNVIKVIAAEVEDITSRFSKGITENDLRIASVKVGIININKQITRLRKEINESNIKLRGPEFNELPKRIRIEYKQARLLSEKHLSRLLKFQNNLAQVRTQIDTSATNAVLIQTLSESNEVIKSINGYIGSTEKVEDLLDEIKEGHDRTEEVNDLLAHYNKGQDEEAEEEIERELEQLELDEKNNNKEENKNQDLHEPKESSSEDLLKRLNNLKINTNEGPVQDNENHDNEIRKIMMEEQPR
What are the official names of this protein?
Uncharacterized protein YJL049W.
Protein: MSCL_YERPG
Sequence: MSFMKEFREFAMRGNVVDLAVGVIIGAAFGRIVSSLVADIIMPPLGLLLGGVDFKQFHFVLRAAEGTIPAVVMNYGTFIQSIFDFVIVALAIFSAVKLMNKLRREKAEEEPATPPAPTTEEILLAEIRDLLKAQHTK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEPK2_ARATH
Sequence: MRKKRKGSETEGWENLPDDLSCSTASRSSNFRSHFSLEGYARLKKRCKETEAVESVGSFKRRIAGVATAPPCGASSLVSSGRGLKRKIGCIDVSTQTGRKNKIDDDYVFGRNIGKGKFGSVRICKSRKNGTEFACKTLKKGEETVHREVEIMQHLSGHPRVVTLHAVYEESDCFHLVMELCSGGRLIDQMVKVGRYSEQRAANIFKDLMLVINYCHEMGVVHRDIKPENILLTAAGKIQLADFGLAMRIAKGQTLSGLAGSPAYVAPEVLSENYSEKVDVWSAGVLLYALLSGVLPFKGDSLDAIFEAIKNVKLDFNTGVWESVSKPARDLLARMLTREESARITADEVLRHPWILFYTDRTLKTMCIKSKHKSQAGSSTCLQNRSPTEKTDLNRADREKKIPSDSPTDSFSNTEEEEDESGVVDVLVVAIANVRISEPKRSRVCSPTNNPIEQQHSSNLTSTSTLCRAF
What are the official names of this protein?
Serine/threonine-protein kinase PEPKR2, Protein PHOSPHOENOLPYRUVATE CARBOXYLASE-RELATED KINASE 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: C3H63_ORYSJ
Sequence: MAAAPSAGGVGEGSSSSAAAAAAAAAATIGPHVVDEEAMWQMNLGEAMEAGPYPERIGEPDCSYYMRTGLCRFGMTCKFNHPADRKMAVAAARMKGEYPQRIGQPECQYYLKTGTCKFGATCKFHHPREKAAIATRVQLNALGYPLRPNEKECAYYLRTGQCKFGSTCKFHHPQPSNTMVAVRGSVYSPGQSVTSPSQHTYPGAVTNWPLSRSASFIASPRWPGHSSYAQVIVPPGLVQVPGWNPYAAQIGSSSSDDQQRTAGGAQYYTGSRHSETPNMGDQGMFSSYQAGSVPLGLYTVQRESIFPERPDQPECQFYMKTGDCKFGAVCKFHHPKERIIPTPNCALSSLGLPLRPGEPICTFYSRYGICKFGPNCKFDHPMGTVMYGLATSPTGDVSARRMLAPVPAHSEVSPDNVSGRSRRITHSDSQQIPSGERGTEREAS
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 63, OsC3H63.
Protein: GBA3_PONAB
Sequence: MAFPVGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQALEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKKWITINEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYNSLFRKEQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEIVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVRKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKVIRNNGLEAHL
What is the function of this protein?
Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides.  Has a significant glucosylceramidase activity in vitro.  However, that activity is relatively low and its significance in vivo is not clear.  Hydrolyzes galactosylceramides/GalCers, glucosylsphingosines/GlcSphs and galactosylsphingosines/GalSphs.  However, the in vivo relevance of these activities is unclear.  It can also hydrolyze a broad variety of dietary glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens in vitro and could therefore play a role in the metabolism of xenobiotics.  Possesses transxylosylase activity in vitro using xylosylated ceramides/XylCers (such as beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine) as xylosyl donors and cholesterol as acceptor.  Could also play a role in the catabolism of cytosolic sialyl free N-glycans.
What are the official names of this protein?
Cytosolic beta-glucosidase, Cytosolic galactosylceramidase, Cytosolic glucosylceramidase, Cytosolic glycosylceramidase, Cytosolic GCase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: QDR2_CANGA
Sequence: MMEDQQSLHSFISDYDQRSHAVEKYDGPDLSEVDSEDNDKMIKTNEDEAVKEPIYRTRSNQTEPDIANAPPYSRFDAKYKMALVLQCAYTGLFSTMAGAIYYPVLSVIEKQFHITEELVNITVVVYFIFQGIAPTLMGGLADSLGRRPVVLFAVTVYFGACIGLACAQTYAQIVVLRCLQAAGISPVIAINSGIIGDVTTRAERGGYVGYISGFQVLGSAFGALIGAGLSSRWGWRSIFWFLAIGSGVCLVFSIIMLPETKRTIVGNGSVTPRNYLNRAPLLMFPLIRRKLHLDDPEYETLEPRTQLSLLAPLSILKVKEISILLVTAGIQFATWSTHQTALSTVLSKNYHLSVAKIGLCYLPTGICTLISIVTSGRYLNWSYRRRFAKHKVWLKEQEEILVKENGYSREEVQNIINNDPKYVFNLVQTRLHAAFVTLLLSSSGFVAFGWCIDVKAPLASVLVMSGFASLFSNCILTFSTTLIVDIFPSKTSTATGCLNLFRCLLSALFIGCLSKMATSMTYGGVFTFLGALTALSACPLFYLLKNGREITLKRKRKEDASRAFALSVANEKAEAEGKAEESR
What is the function of this protein?
Multidrug resistance transporter involved in resistance to the antifungal drugs miconazole, tioconazole, clotrimazole, and ketoconazole; as well as to quinidine (PubMed:23629708, PubMed:27148215).  Decreases the intracellular accumulation of clotrimazole in and plays a role in the extrusion of this antifungal from preloaded cells (PubMed:23629708, PubMed:27148215).
What are the official names of this protein?
Multidrug transporter QDR2, Clotrimazole exporter QDR2, Drug:H(+) antiporter QDR2, DHA QDR2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RTC5_ARTGP
Sequence: MGAGQSTDTKGHGTSPEEMSRILAQRFASKCFTPLELAHLKDNFNSLALKQDDVRYWNEEVLSKFLGIPDGDKTLGHGPFDAGPVIFRMVSYLGAFPFQNTLAPSVLTFDAMVKVIVLLTDRYGKVLRRGRKDRIKLLFGSLADVGRKEEPSLEAGDLEQSPVEIKPHEAGFSVDKPSNDTDDYHDDDDLVLAALESLDAIEVFKHDQRIDRTVYEARISFDTFQRLLMLLVIIAPLRAFEKTTDYFSQLDEESLKSARCSVDSILTSFDAGDRTNGIDYETFSWVISTSLPYMFDPLTALFEHLLFSKNLDLSRRKDSGTCSVNEEKQKHAELSPTPSDPAIILPGSFKPCILDSAIISHLSFFLPTASPIPNILQNGIRLHGVFSSNTHGESLTSFSHNVLTWDAPSVILVTGALNHPSAGEADTITVGAYLPHTWRSPTFGSASHYDTSDQSQLPCLFQLSPRHVMMQGSPSINSLKANLPVVSFSTKSGIAIGCKIPPPTRTSMDSSRPTPAGSGSMWIDPALENAEFVMSNGLSHEEGVFLPPGLATWSPSRSSCEAESETIKISIYTIEVWGIVRTTSTPTQSPFNHSRASTANGDIPDAIARQQANWSFEAREAERRREIHLNVGGGDSEEQTGRALLEMAGIIGDSARHR
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_LIMRD
Sequence: MSNSPEIGSRTRTRAIMEKYGIRTKKSFGQNFLTDLNVLKNIVEAADITANDNVIEIGPGIGALTEQLAQAAGEVLALEIDQDLIPVLKEVLSPYDDVKVINQDVLQANLPELIKKEFKDPSRPIKVVANLPYYITSPILMNLLASPVEWATICVMMQKEVAQRLTAKPGTKQYGALTLAIEYQMQAKIAFDVSRKVFVPAPNVDSAIVVLTPRTNPLPVQPFDKQKLFGFIRGCFAHRRKSLWNNLQSVIGKDPAAKEKMTAVLNQLDISPQIRPEKLTLEQFIELANALHQQNLL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.