PharMolix/UniProtQA huggingface dataset:
Protein: LEG9_MOUSE
Sequence: MALFSAQSPYINPIIPFTGPIQGGLQEGLQVTLQGTTKSFAQRFVVNFQNSFNGNDIAFHFNPRFEEGGYVVCNTKQNGQWGPEERKMQMPFQKGMPFELCFLVQRSEFKVMVNKKFFVQYQHRVPYHLVDTIAVSGCLKLSFITFQNSAAPVQHVFSTLQFSQPVQFPRTPKGRKQKTQNFRPAHQAPMAQTTIHMVHSTPGQMFSTPGIPPVVYPTPAYTIPFYTPIPNGLYPSKSIMISGNVLPDATRFHINLRCGGDIAFHLNPRFNENAVVRNTQINNSWGQEERSLLGRMPFSRGQSFSVWIICEGHCFKVAVNGQHMCEYYHRLKNLQDINTLEVAGDIQLTHVQT
What is the function of this protein?
Acts as an eosinophil chemoattractant (By similarity).  It also inhibits angiogenesis (By similarity).  Suppresses IFNG production by natural killer cells.
What are the official names of this protein?
Galectin-9, Gal-9.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=May also be secreted by a non-classical secretory pathway (PubMed:9038233). Secreted by mesenchymal stromal cells upon IFNG stimulation (By similarity).
Protein: EBSA_ENTFA
Sequence: MKKQKFYWQPELASTIIYWSCTFCILFISLILALENNGPYLISNLVMVPFFVFAYLGIARSFNMTETSLIVRDVLWFRKKALPLSQIEKVTYNEKSIEIFSSEFKEGSKVFLMKKKTIPLFLEALKVKKPELKVAEDHSLGLHKKEEKNKSES
What is the function of this protein?
Seems to play some role in the cell surface expression of a chromosomally encoded receptor, named enterococcal binding substance (EBS), that mediates mating aggregate formation.  Might interfere with the synthesis or assembly of EBS, and/or assist in the localization of EbsB to the cell wall.
What are the official names of this protein?
Protein EbsA.
What is the protein family that this protein belongs to?
Belongs to the EbsA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YNSK_SCHPO
Sequence: MPLKLALPRSTTPKDPARCTLDIRMESPPLVFLGSPETSSGALASGILKLTILHQPFIKVHTLKLQLIKRITVLHPAISHCSACAGSKEVLQTWDLAANTTYRPGTQHWPFSWLFPGSLPASVSNRYIKLEYYLEATLCYGTPEGGISPSKPEVLKFPLQLKRAAIPSPDTIHKRIFPPTNLVANITLPSTLHPHGAALMEVTMTGFAQNDGNDWKINRVTWRLEEHMQFSCQPCERHRDLVKPRPIEEKRILSTQDLQSGWKFIDNQMFLSTQINTSSLREPSCDVEIPAPFSLKVSHHLIFETIVNRKKNVAGNNMGNARILRVSVVQPLTTPAGLGISWDEECPPVFESVGPAPPAYT
What are the official names of this protein?
Uncharacterized protein C18H10.20c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AMYB_WHEAT
Sequence: MAGNMLANYVQVYVMLPLDVVSVDNKFEKGDEIRAQLKKLTEAGVDGVMIDVWWGLVEGKGPKAYDWSAYKQVFDLVHEAGLKLQAIMSFHQCGGNVGDVVNIPIPQWVRDVGATDPDIFYTNRGGTRNIEYLTLGVDDQPLFHGRTAVQMYADYMASFRENMKKFLDAGTIVDIEVGLGPAGEMRYPSYPQSQGWVFPGIGEFICYDKYLEADFKAAAAKAGHPEWELPDDAGEYNDTPEKTQFFKDNGTYLTEKGKFFLSWYSNKLIKHGDKILDEANKVFLGCRVQLAIKISGIHWWYRVPNHAAELTAGYYNLDDRDGYRTIARMLTRHHASMNFTCAEMRDSEQSEEAKSAPEELVQQVLSAGWREGLHVACENALGRYDATAYNTILRNARPKGINKNGPPEHKLFGFTYLRLSNELLEGQNYATFQTFVEKMHANLGHDPSVDPVAPLERSKPEMPIEMILKAAQPKLEPFPFDKNTDLPVKDHTDVGDEVLVAPV
What are the official names of this protein?
Beta-amylase Tri a 17, 1,4-alpha-D-glucan maltohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 14 family.
Protein: DNJC5_HUMAN
Sequence: MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN
What is the function of this protein?
Acts as a general chaperone in regulated exocytosis (By similarity).  Acts as a co-chaperone for the SNARE protein SNAP-25 (By similarity).  Involved in the calcium-mediated control of a late stage of exocytosis (By similarity).  May have an important role in presynaptic function.  May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily C member 5, Ceroid-lipofuscinosis neuronal protein 4, Cysteine string protein, CSP.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane. Melanosome. Cell membrane. Note=The association with membranes is regulated by palmitoylation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).
Protein: PSRP_DEIGD
Sequence: MTPPSRTVLIVSDHTGLTAETTARALLAHFPSQSLKYLQRPFVASVEVARGVAREVAALAERGERPLIFTTITEPAVMRELEAAPARVFDLLGPGLIALEHEFGEKAARSVGRYHDMHDQTSYLARMDALDFALATDDGLGDRQYGLADVILVGVSRAGKTPTSLFLALQHSVRASNYPLAEDDFERESLPIPLEPHRAKLHGLTIDPRRLHAIRTQRKPGSRYASLEQCEYEVRQAERLFGRAGIPVRDTTSASVEEIAAGILAQLRRG
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: RLMM_ALIF1
Sequence: MFYCRSGFEKECAGEIQDKATQLEVFGFPRLKNNTGYVLFECYQEGDADRLIREIKFNELIFARQMFAVAAEVSDLPKDDRISPILDALSDVDGVPCCGDIRIETPDTNEAKELLKFCRKFTVPMRQALRGKKMLTERDSNRIPVLHICFIAPGHCYVGYSYTNNNSQFFMGIPRLKFPADAPSRSTLKLEEAFHVFIPKEEWDDRLASGMWGVDLGACPGGWTYQLVKRSMFVHAIDNGMMAQSLMDTGQVKHHMVDGFKFEPPRKNVTWLICDMVEKPARVAHLMGEWLIKGWAKEALFNLKLPMKGRYDEVLQDIENLKDFLKKNGFQYKLQAKHLYHDREEITVHIQAISNISPH
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPED_YERPA
Sequence: MSKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYIAYIDEQYNANRLTEILSETCSIIGANILNIARQDYDPQGASVTILVSEEPVDPRDVDTSEHPGPLPSAVVAHLDKSHICVHTYPESHPEAGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTMDYRVRGFTRDINGVKHFIDHKINSIQNFMSDDMKSLYHMMDVNVYQENIFHTKMMLKDFDLKHYLFNAKPEELSAEEKEQITRLLYKEMQEIYYGRNVPEV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: NCPR_DROME
Sequence: MASEQTIDGAAAIPSGGGDEPFLGLLDVALLAVLIGGAAFYFLRSRKKEEEPTRSYSIQPTTVCTTSASDNSFIKKLKASGRSLVVFYGSQTGTGEEFAGRLAKEGIRYRLKGMVADPEECDMEELLQLKDIDNSLAVFCLATYGEGDPTDNAMEFYEWITSGDVDLSGLNYAVFGLGNKTYEHYNKVAIYVDKRLEELGANRVFELGLGDDDANIEDDFITWKDRFWPAVCDHFGIEGGGEEVLIRQYRLLEQPDVQPDRIYTGEIARLHSIQNQRPPFDAKNPFLAPIKVNRELHKGGGRSCMHIELSIEGSKMRYDAGDHVAMFPVNDKSLVEKLGQLCNADLDTVFSLINTDTDSSKKHPFPCPTTYRTALTHYLEITAIPRTHILKELAEYCTDEKEKELLRSMASISPEGKEKYQSWIQDACRNIVHILEDIKSCRPPIDHVCELLPRLQPRYYSISSSAKLHPTDVHVTAVLVEYKTPTGRINKGVATTYLKNKQPQGSEEVKVPVFIRKSQFRLPTKPETPIIMVGPGTGLAPFRGFIQERQFLRDEGKTVGESILYFGCRKRSEDYIYESELEEWVKKGTLNLKAAFSRDQGKKVYVQHLLEQDADLIWNVIGENKGHFYICGDAKNMAVDVRNILVKILSTKGNMSEADAVQYIKKMEAQKRYSADVWS
What is the function of this protein?
This enzyme is required for electron transfer from NADP to cytochrome p450 in microsomes.  It can also provide electron transfer to heme oxygenase and cytochrome b5 (By similarity).  May function to clear the olfactory organ (antennae) from accumulating chemicals.
What are the official names of this protein?
NADPH--cytochrome P450 reductase, CPR, P450R.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: ATPA_STRPC
Sequence: MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGLDNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL22_BACCQ
Sequence: MQAKAVARTVRIAPRKVRLVVDLIRGKQVGEAIAILNHTPKTASPVVEKVLKSAIANAEHNYEMDINNLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: AROD_PYRFU
Sequence: MPKLAGVIIAKTIEEAVKKIKLHEADLYELRVDYLESMENIELLLPHSNKLIVTVRKVEEGGAKRIEEQERLKLFEKFAKIKPAYFDVELYSNIVEDVINLSSKIGSKVILSYHNFSKTPSYQTLQSILDSMIELEPDIIKIVTYARDFRDNIEVIKLYENSENLIAFCMGEKGKISRIFSALYSPFTYVSIDNSVAPGQFTVGEMRKILELLGETK
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: POED2_ORYSJ
Sequence: MESEGWPALQPLLCFAWIAATLPIIAAALPIPTAVGGHLLRRLLSAFSSRGKTVRPSPASSSGSSSSKAKFTVPQKYFMHFYVVGVLATTILLLAIWFYAYMKLTPLLLESSSYSTIFSHLVGSNSFSFGRVRSRTMGHKYRVWRTVFALLLMEVQVLRRLYETEHVFHYSPARMHIVGYLTGLFYYVAAPLSLASSCIPEAAEYFQGQVPEFVVKGRARMPDLVIDSSSLLQPLLKLGWTQWIGAVIFIWGSLHQIRCHAILGSLREHKDYDEYVIPCGDCFNRVSCPHYLAELVIYFGMLVASGAEDIPVWFLFIFVITNLSFAAVETYNWYLQKFEDYPRSRYAIIPFVC
What is the function of this protein?
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol.  Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.  Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (By similarity).
What are the official names of this protein?
Polyprenol reductase 2.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y7194_PARXL
Sequence: MMLHLQGVLSKQQVAQCREVLDAAQWIDGNVTSGEQSAQAKRNQQLPEGSAAARAVGDAIQDALGRNPRFFSAALPLKVFPPLFNRYAGGDGFATHVDNAIRQLRGTDFRIRSDLSATLFLAEPDTYEGGELCIEDTYGVHRARLPAGDMVLYPASSLHHVSPVTRGVRVASFFWIQSMVRDDGERATLFQLDNDVQRLAAEKGSNDATVVSLTGIYHNLLRRWADA
What are the official names of this protein?
PKHD-type hydroxylase Bxeno_B2194.
Protein: SERA_MYCBO
Sequence: MSLPVVLIADKLAPSTVAALGDQVEVRWVDGPDRDKLLAAVPEADALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAADASLREHTWKRSSFSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVGGGVVNEEVAPWLDLVRKLGVLAGVLSDELPVSLSVQVRGELAAEEVEVLRLSALRGLFSAVIEDAVTFVNAPALAAERGVTAEICKASESPNHRSVVDVRAVGADGSVVTVSGTLYGPQLSQKIVQINGRHFDLRAQGINLIIHYVDRPGALGKIGTLLGTAGVNIQAAQLSEDAEGPGATILLRLDQDVPDDVRTAIAAAVDAYKLEVVDLS
What is the function of this protein?
Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway.  Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
What are the official names of this protein?
D-3-phosphoglycerate dehydrogenase, PGDH, 2-oxoglutarate reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: DAPB_ANAMM
Sequence: MKIGIVGCLGRMGRIIVQEVVGTGGVELSGGVVRRGNGLVGEDMGAVLGCGHGAKITDSKEFLFDCSDVVIDFSSPECMLECVGIASEKRVPLVSGTTGVDERDFRTHAEKVPLLWSCNMSLGVTLLLELVKMAAAGFRGYDVEIRELHHRAKKDAPSGTSLMLGKAVAQGMGVELESQQHTFGSGCRRSGAVGFSVARGGGVIGDHAVMFLGDDEIVELQHRAIDRRVFARGAIKAACWLVGKPAGLYTMSDVLRA
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_PARPJ
Sequence: MDLDQIVADAQKAFAEASDVTTLENEKARFLGKSGALTELLKGLGKLDPETRKSEGARINLVKQQVEAALTARRQALADVLLNQRLAAEAIDVTLPGRGTGAGSLHPVMRTWERVEQIFRTIGFDVADGPEIETDWYNFTSLNSPENHPARSMQDTFYVDGKDADGRQLLLRTHTSPMQVRYARTNTPPIKVIVPGRTYRVDSDATHSPMFNQVEGLWIDENISFADLKGVYTDFLKKFFERDDILVRFRPSYFPFTEPSAEIDMLFETGKNAGKWLEISGSGQVHPTVIRNMGLDPDRYIGFAFGSGLERLTMLRYGVQDLRLFFENDLRFLRQFA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOE_OCEIH
Sequence: MSLQQLTHDEIDHLSMIELGVKILKEENKAMNYKVIFNKIAELKDFTDEQKQNMMAQFYTDMNVDGRFLTLGSGMWGLKRWYPVEQAEEEITEEPKKKTKKKKKKAEVIDDVDDDLDVTDDEIDDIVSDLGDDLDDDDFEDDLDEDLEDLEDEVDELEADEDVEDENDDDNTR
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: ATPB_ANTAG
Sequence: MKTNYLILGVSTLISKNVGHISQIIGPVLDVTFPPGKMPNIYNSLIVRGQNPAGQEINVTCEVQQLLGNNKVRAVAMSATDGLTRGMKVTDTGAPLSVPVGEVTLGRIFNVLGEPVDNLGAIDVSTTFPIHRSAPAFTQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESKVINEQDISESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPWIVGEEHYETAQGVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVSLIETIKGFQMILAGELDGLPEQAFYLVGNIDEVTAKAETLQMES
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RL14_HELPG
Sequence: MIQSFTRLNVADNSGAKEIMCIKVLGGSHKRYASVGSVIVASVKKAIPNGKVKRGQVVKAVVVRTKKEIQRKNGSLVRFDDNAAVILDAKKDPVGTRIFGPVSREVRYANFMKIISLAPEVV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: DPO4_STRM5
Sequence: MTRLRKIIHVDMDAFYASVEQRDDPSLRGKPVVVAWRGARSVVCAASYEARVFGVRSAMPAVRAERLCPDAIFVPPDFARYKAVSQQVREIFLRHTDLVEPLSLDEAYLDVTEPKSGMELATDIARTIRAQIREETQLTASAGIAPNKFLAKIASDWRKPDGQFVIPPQRVDAFLLPLPVNRVPGVGKVMEGKLAARGIVTCGDLRQWALIDLEEAFGSFGRSLYNRARGVDERPVEPDQQVQSISSEDTFAEDLPLEDLGEAIVQLAEKTWNATRKTERVGHTVVLKLKTAQFRILTRSFTPERPPESMEELRDIALALRARVDLPADTRYRLVGVGLSGFRDKEPVVQGELFEH
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_BRUC2
Sequence: MSTKIAVLGGGAWGTALAAMAAKGGHESWLYARDAETVVAINKDRRNPRYLGDITLADGIRASTDAAAVVTGADAVLAVIPAQAMRNGLSELGTLIPQASPIVLCAKGIEQNTGRLMSEVVAEILPDHRIAALSGPSFASDVARGLPTAVTVACEDANTADRLAALLSGPAFRCYSTTDLKGVETGGALKNVLAIAAGAAIGRGYGASAQAALVTRGFAELRRIGQAMSARPETIMGLSGLGDLMLTCSSSQSRNYSYGLALGRGEDLTSRPLAEGVATAPIAAELCRKHNISAPIIDAVGALLDGKITIDEAVTALLNRPLKTED
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_SALDC
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTARKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAHDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_KOSOT
Sequence: MKISPSEITKIIEEQLKRSDREIDYFEAGRIIQVGDGIARAYGLKGVMSNELVQFENGEYGLALNLEEDNVGIVVLGDYREIKEGDLVKRTGRIIEVPAGEALLGRVVNPLGIPLDGKGPIEASEHRPVEIKAPGVVMRKPVDTPLQTGIKAIDAMIPIGRGQRELIIGDRQTGKTAIAIDTIINQKDQGVYCIYVAIGQKTAVLARIIDKLEETGAMEYTTIVAATANDPATLAYLAPYAGAAMGEYFMYSGKDALVIYDDLSKHAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAARLNEEHGGGSLTALPIIETLANDVSAYIPTNVISITDGQIYLDPNLFYAGNRPAINVGLSVSRVGGSAQIKAMKKIAGSLRLDLAQYRELLAFAQFSTELDKATQAQLIRGEKLTELLKQEQYSPMPVEEQIAVLYAGTRGYLDDLPTDKIRQFEKQLLQTMRQKYADVLKAIREKKDMTEEIEAGLKKAVEDVRQAFVS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSMD4_DROME
Sequence: MVLESTMICFDNSDFQRNGDYFPTRLIVQRDGINLVCLTKLRSNPENNVGLMTLSNTVEVLATLTSDAGRIFSKMHLVQPKGEINLLTGIRIAHLVLKHRQGKNHKMRIVVFVGSPINHEEGDLVKQAKRLKKEKVNVDIVSFGDHGNNNEILTAFINALNGKDGTGSHLVSVPRGSVLSDALLSSPIIQGEDGMGGAGLGGNVFEFGVDPNEDPELALALRVSMEEQRQRQESEQRRANPDGAPPTGGDAGGGGGVSGSGPGNEESAGAENEANTEEAMLQRALALSTETPEDNLPDFANMTEEEQIAFAMQMSMQDAPDDSVTQQAKRPKTDEANAPMDVDEDYSEVIGDPAFLQSVLENLPGVDPQSEAVRDAVGSLNKDKDKKSDGKDSQKK
What is the function of this protein?
Binds and presumably selects ubiquitin-conjugates for destruction.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 4, 26S proteasome regulatory subunit RPN10, 26S proteasome regulatory subunit S5A, 54 kDa subunit of mu particle, Multiubiquitin chain-binding protein, p54.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5A family.
Protein: WNK6_ARATH
Sequence: MEGTDDASALQEPPDPEVLEVDPTFRYIRYKEVIGKGAFKTVYKAFDEVDGIEVAWNQVRIDDVLQSPNCLERLYSEVRLLKSLKHNNIIRFYNSWIDDKNKTVNIITELFTSGSLRHYRKKHRKVNMKAVKNWARQILMGLRYLHGQEPPIIHRDLKCDNIFINGNHGEVKIGDLGLATVMEQANAKSVIGTPEFMAPELYDENYNELADIYSFGMCMLEMVTFDYPYCECKNSAQIYKKVSSGIKPASLSRVKDPEVKQFIEKCLLPASERLSAKELLLDPFLQLNGLTMNNPLPLPDIVMPKEGAFGDRCLMSEGPPTTRPSKTLSIDLDEDSNLPIVTFSDNSGSRCIEVRRAKRGNFFVLKGEENDEQSVSLILRIVDENGRVRNIHFLFYQEGDTASKVSSEMVEQLELTDQNVTFIAELIDILLVNMIPTWKTDVTVDHLIHSQLNQNSRSHHNEAKPQKQEETVFHDTCELVSHSCNSDCPRSDEEDKQCVDATKGEDKSSIQEVEEATEPVSLEEEERLRQELEEIEAKYQEDMKEIATKREEAIMETKKKLSLMKLK
What is the function of this protein?
May regulate flowering time by modulating the photoperiod pathway.
What are the official names of this protein?
Probable serine/threonine-protein kinase WNK6, AtWNK6, Protein kinase with no lysine 6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily.
Protein: MD19A_DANRE
Sequence: MTEIFSTLFGQNDAQPPSGPAALGFAPGKPPPSMPPNQAPIAAQMPGQLGDDGPLLRKPGAMNEPFYLLRELPVGNDLTGNTNLITHYNLEHAYNKFCGKKVKEKLSNFLPELPGMIDCPGVQDGSSLRSLIEKPPVCGNSFSPLTGALLTGFRLHTGPLPEQYRLMHIQPPKKKSKHKHRHHHPQDPLPLETRTDPTKKKKKKDNEPERRKKKKDKKKKKNRHSPDHPGVTGSQPNSNSLR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 19-A, Mediator complex subunit 19-A.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRM1_METS5
Sequence: MKLTEVIEGKARLVIPDPSEFSREGKFDPAWSPVFYNPRMVFNRDVSVLAVSVISPPSVLDAMSATGVRGIRYVKESGVKGEVLFNDKNPVSVELISKNLELNGITGKVLRSDANSLMHQVKVGYTDLDPFGSPAPYLFSAISSLRRKGVLGVTATDLSALEGKSRTSSKRKYGVQGSRLSYSKEAGLRVLLGKIVKEASVQEKGIRPLMGFYHDYYYRLFVKMEDGAKRADRSLESLGTLYECDRCGYSFMSSDECERKCPVCGGELKYYGPAWIGEFNDLEFLKEMKNRLTEFSYLSNSVKISELLEYLERENRFGPYYRVDVLASRLKVNMPPMNSLLGCLGDAVRTHFDPRGFKSFREFSEILECVKGSSATYETSGR
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.