PharMolix/UniProtQA huggingface dataset:
Protein: DEOD_BACAC
Sequence: MSVHIEAKQGEIAESILLPGDPLRAKYIAETFLEDVTCYNNVRGMLGFTGTYKGKRVSVQGTGMGVPSISIYVNELIQSYGVKNLIRVGTCGAIQKDVKVRDVIIAMTACTDSNMNRLTFPGFDFAPAANFDLLKKAYDAGTEKGLHVRVGNVLTADVFYRESMDMVKKLGDYGVLAVEMETTALYTLAAKYGVNALSVLTVSDHIFTGEETTSEERQTTFNEMIEIALDAAIQQ
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: HSPQ_ECOL6
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVNDELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI_SALPK
Sequence: MTEEHVVLLDEQDKPSGTLEKYAAHTLNTPLHLAFSCWLFNEDGQLLVTRRSLSKKAWPGVWTNSVCGHPQQGETTEEAIIRRCRFELGVEITDLTPVYPHFSYRATDPNGIVENEVCPVFAARATSVLQVNSEEVMDYQWSEFKSVWKSLLATPWAFSPWMVMQASDEQARERLLNYCQR
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDOR1_ARATH
Sequence: MGEKQRKLLVLYASQTGNALDAAERIGREAERRGLPASVVSTDEFDTSSLPHHEEAVVFVVSTTGQGDSPDSFKAFWRFLLQRNLGNYWLQQVRYAVFGLGDSGYQKYNFVAKKLDKRLSDLGATTIIEKGLGDDQHPSGYEGTLDPWMLSLWRTLYQINPKYFPKGPDVKIPQDEVIDKPKYRILFHKQEKLEPKLLSDSDIIQRARGMSPGKLFKDKSKPDCFLKMTRNEVLTKAESTKDVRHFEFQFVSSTIEYEVGDVVELLPSQNSSVVDAFIERCGLDPESFITVGPRETENSSFSEEMITQIPIKLKTFVELTMDVTSASPRRYFFEIMSFYATAEHEKERLQYFASPEGRDDLYNYNQKERRSILEVLEDFPSVQIPFDWLVQLVPPLKPRAFSISSSPLAHPAAVHLTVSIVSWITPYKRTRKGLCSSWLASLAPEQEVNIPVWFHKGSLPAPSQSLPLILVGPGTGCAPFRGFIAERAVQAQSSPVAPVMFFFGCRNKDTDFLYRDFWESHAREGGMLSEGKGGGFYTAFSRDQPKKVYVQHKIREMSKRVWDLLCDGAAVYVAGSSTKMPCDVMSAFEDIVSEETGGGSKEVASRWLKALEKTGRYNVEAWS
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of the anamorsin/DRE2 homolog, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins (By similarity).  Catalyzes the NADP-dependent reduction of cytochrome c, but not cytochrome P450 in vitro.  Required for embryo development (PubMed:20406405).
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: OLSE_RHITR
Sequence: MIFQSSSRLYAAVSSLLWPAILCAGLTGAYFAFRSDMHLLWFNVVYLSTVAIIALFERLMPYEKTWQKRDGETFNDIAHTLLTKGGVQIAAAIGTSFPMAVATVAQPALSYHSHFWPDQWPMAFQVVLGLVIAEFGLYMAHRLAHEHLSLWRFHALHHSVGRLWVINTGRFHFIDTLFKIALGQIPLYLLGAPLPVFLWIGAVTAFIGLLTHCNVDMRTGPLDLIFSTPRLHRWHHSKVLAEGNTNYGENLVIWDQLLGTFHNPPRPSSTDIGITGKVAKGFLAQLAQPFSRKGRKEIIGKKPKELILQEEQAAKAAAARRNANAKIRKSG
What is the function of this protein?
Involved in the biosynthesis of ornithine lipids (OLs), which are phosphorus-free membrane lipids (PubMed:21205018).  Is responsible for the hydroxylation of OL within the ornithine moiety (PubMed:21205018).
What are the official names of this protein?
Ornithine lipid hydroxylase OlsE, OL hydroxylase OlsE.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
Protein: ENGB_ANADE
Sequence: MPIQVVSADFDKTATRPEEWPRGATPEIAFVGRSNVGKSSMLNALARRKGLARVSSTPGRTRALQFFDLSYRPTPAARPRAIRFCDLPGYGYAKVSRAERDRWTAMIEDYLRDRDVLRAVVLIVDARHAPSESDEDAAAFLVSAGRRLVVAATKTDKLPKARRVLALQQVERALGLARGDAVPFSAVEGTGTDALWARLAALAAEEARTAEADPPA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PF36P_PLAF7
Sequence: MYVLVLIHMCYHFTMKRKKLFVYFIFLSFIINFNFNININFVCSNVIQDVISIGNVDICVVNVNSDEAQECILNNEFGKLLLFVCNMNDAFSTTAKTHPENCPSRAFVNQSNPTENSPEVDTYSIYPNLFGTNENRLNDTYSLYSTPYSNMDIDFSCLCYGDKQDKVKHIMRINIKKTRKKIKGCDFGDNIPSKRDLTNSLSLNERSSCIIHAYSNDVLGINCFKKEINNSYNNNLELNPSNCFHDVYFGADLILNSKNVIPNSRVIPDPSSDVKLSRNHSFSSYLILPNNLTENIKISCTCKRDEFVGTMIIYTKNINSLMFDNNNNNNDEEQIFQNKYMKKKEYKKDEGNEYDKKMNTDDNYINNEEHHNNNQYNNYENKINNVNYNYDDISKYINEHYKNYDHEKNSKNSYKTNTNIHDQYDTYHYNNKYDLHSDRTRIRTRTFWQNLFGLSSSKYILFNNFLILFIFLIYIYST
What is the function of this protein?
Involved in sporozoite infection of hepatocytes and replication therein.
What are the official names of this protein?
Sporozoite surface protein P36p, Sporozoite surface protein P52.
What are the subcellular locations of this protein?
Cell surface. Cell membrane; Lipid-anchor, GPI-anchor. Note=Present on the surface of sporozoites.
Protein: PTGES_MACFA
Sequence: MPAHSLAMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLLGRVVHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
What is the function of this protein?
Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway.  Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli (By similarity).  Plays a key role in inflammation response, fever and pain (By similarity).  Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2.  In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively (By similarity).
What are the official names of this protein?
Prostaglandin E synthase, Glutathione peroxidase PTGES, Glutathione transferase PTGES, Microsomal glutathione S-transferase 1-like 1, MGST1-L1, Microsomal prostaglandin E synthase 1, MPGES-1.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cytoplasm, perinuclear region. Note=Colocalizes with PTGS1/COX-1 and PTGS2/COX-2 in the perinuclear compartment.
Protein: LOLD_ANAMM
Sequence: MTTVLEILDVSKCYGRRNRVCVLSNINLKIQRGEFAALIGSSGSGKSTLLHIASLLEVPTSGTVVLNGTVCAPASDKTRTMMRRKHMGFVYQFHHLLQEFSVLENVMLPQRILGHGASTAESVAAAILEEMGLQDKAECRISELSGGERQRVAVARGIVNSPTIILADEPTGSLDPQMSKAVFSVLHKHVKAKNLAGLVATHDRTLAKQTDRVLSLSGGMLTEL
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MATRX_RABVP
Sequence: MNFLRKIVKNCRDEDTQKPSPVSAPLDDDDLWLPPPEYVPLKELTSKKNRRNFCINGGVKVCSPNGYSFGILRHILRSFDEIYSGNHRMVGLVKVVIGLALSGAPVPEGMNWVYKLRRTLIFQWADSRGPLEGEELEYSQEITWDDNTEFVGLQIRVSAKQCHIRGRIWCINMNSRAGQLWSDMSLQTQRSEEDKDSSLLLE
What is the function of this protein?
Plays a major role in assembly, budding and uncoating of virion after membrane fusion.  Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form.  Inhibits viral transcription and stimulates replication.  Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons.
What are the official names of this protein?
Matrix protein, Phosphoprotein M2.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus matrix protein family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host endomembrane system; Peripheral membrane protein. Host cytoplasm.
Protein: PCKA_BACC1
Sequence: MSTVNVQIGLHELLNGSNAQIQLSVPQLVEKVLMRDEGKLTSTGAVSASTGKYTGRSPKDKFIVKEASVADKIAWGAVNQPISEEHFNKLYTKVLEYLKEKEELFVFKGFAGADRNYRLPIQVINEYAWHNLFVHQLFIRPTEEELTTHESEFTIVSAPNFKADPAVDGTNSEAFIMVSFEKRIVLIGGTEYAGEMKKSIFSIMNFLLPEQDILSMHCSANVGEEGDVALFFGLSGTGKTTLSADPNRKLIGDDEHGWSDNGVFNIEGGCYAKCVNLSHEKEPQIFDAITFGSVLENVIINDQTRIADYNDTTLTENTRAAYPMHAIDNIVLPSVAGHPNTIIFLTADASGVLPPISKLSKEQAMYHFLSGYTSKLAGTERGVTSPQATFSTCFGSPFLPLDASRYAEMLGEKIEKHDAKVFLVNTGWTGGEYGVGKRMNLGYTRAMIQAALNGELAKTETAKHDIFGLEVPLHVPGVPDEVLMPEQTWADKAAYKAKAIELANEFKANFKKFDSVSEDIINLGGPIA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDFR_ECOL6
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDVHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFCSQLLGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: DTPA_PROMH
Sequence: MSTANTPEDEQKPSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKMLGMSEAEAITVFAAFTALVYGFVAIGGWLGDKILGTKRVIVLGAIVLAIGYAMVAFSDHDKDMIYWGLATIAVGNGLFKANPSSLLATCYEKDDPQLDGAFTMYYMSINVGSFLSMLATPWLAANYGWDVAFALSVVGMLITLANFMLCRGWIKDKGSRPDFEPLNYLKLLLTLVGIVALTAVSTWLLHNNEVATWSLAIISLGIILIFARETFMMKGVARRKMIVAFLLMVEAVVFFVLYDQMPTSLNFFAIHNVEHAILGFSVEPEQFQSLNPFWIMLASPLLAAIYNFMGDKLPMPYKFTVGMFLSATAFLVLPLGASMANEAGIVSSWWLVASYGFQSIGELMISGLGLAMVAQLVPQRLMGFIMGAWFLTSAAAAIIAGKVASLMAVPEDVQNAHASLEIYSSVFLQIGIVTGVIALLMLFTAPMLSKMTQ
What is the function of this protein?
Proton-dependent permease that transports di- and tripeptides.
What are the official names of this protein?
Dipeptide and tripeptide permease A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CPS4_ORYSI
Sequence: MPVFTASFQCVTLFGQPASAADAQPLLQGQRPFLHLHARRRRPCGPMLISKSPPYPASEETREWEAEGQHEHTDELRETTTTMIDGIRTALRSIGEGEISISAYDTSLVALLKRLDGGDGPQFPSTIDWIVQNQLPDGSWGDASFFMMGDRIMSTLACVVALKSWNIHTDKCERGLLFIQENMWRLAHEEEDWMLVGFEIALPSLLDMAKDLDLDIPYDEPALKAIYAERERKLAKIPRDVLHAMPTTLLHSLEGMVDLDWEKLLKLRCLDGSFHCSPASTATAFQQTGDQKCFEYLDGIVKKFNGGVPCIYPLDVYERLWAVDRLTRLGISRHFTSEIEDCLDYIFRNWTPDGLAHTKNCPVKDIDDTAMGFRLLRLYGYQVDPCVLKKFEKDGKFFCLHGESNPSSVTPMYNTYRASQLKFPGDDGVLGRAEVFCRSFLQDRRGSNRMKDKWAIAKDIPGEVEYAMDYPWKASLPRIETRLYLDQYGGSGDVWIGKVLHRMTLFCNDLYLKAAKADFSNFQKECRVELNGLRRWYLRSNLERFGGTDPQTTLMTSYFLASANIFEPNRAAERLGWARVALLADAVSSHFRRIGGPKNLTSNLEELISLVPFDDAYSGSLREAWKQWLMAWTAKESSQESIEGDTAILLVRAIEIFGGRHVLTGQRPDLWEYSQLEQLTSSICRKLYRRVLAQENGKSTEKVEEIDQQLDLEMQELTRRVLQGCSAINRLTRETFLHVVKSFCYVAYCSPETIDNHIDKVIFQDVI
What is the function of this protein?
Catalyzes the conversion of geranylgeranyl diphosphate to the phytoalexin precursor syn-copalyl diphosphate.
What are the official names of this protein?
Syn-copalyl diphosphate synthase, OsCPSsyn, Syn-CPP synthase, OsCPS4, OsCyc1.
Protein: RL9_FRATN
Sequence: MQVILKEKVENLGVLGDIVNVKPGYARNFLIPFGKAVQATQANIKAFEAQKAELEKAEKARFEAAVAVADAIKDKVYTIAAQAGEGGKLFGSVGTAEVAEAVSNQSGKKVEKSQVRMPEGVIRSVGEFEFTVHVYTDVDADIKVNVVAAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PLPR3_RAT
Sequence: MIAKKEKNKTPKDSMTLLPCFYFVELPIVASSVVSLYFLELTDLFQPAKVGFQCHDRSLSMPYVETNEELIPLLMLLSLAFAAPAASIMVGEGMVYCLQSRLWGRGPGGVEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSCEANPYITQDICSGHDTHAILSARKTFPSQHATLSAFAAVYVSMYFNSVISDATKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPAEKVPTPAPAKDALRVLTQRGHESMYQQNKSVSTDELGPPGRLEGVPRPVAREKTSLGSLKRASVDVDLLAPRSPMGKEGMVTFSNTLPRVSTPSLDDPSRRHMTIHVPLDASRSRQLISEWKQKSLEGRGLGLPDEASPAHLRAPAEQVAEEEEEEEEEEEEEEEEEEEEEGPVPPSLYPTVQARPGLGPRVILPPRPGPQPLIHIPEEVVQAGAGLSPKSSASVRAKWLSMVEKGGGPVAVAPPQPRVANPPRLLQVIAMSKAAGGPKAETASSSSASSDSSQYRSPSDRDSASIVTIDAHAPHHPVVHLSAGSTPWEWKAKVVEGEGGYELGDLARGFRSSCKQPGIGPGSPVSDVDQEEPRFGAVATVNLATGEGLPPPGASEGALGAGSRESTLRRQVGALGEREVEAEAESYYRRMQARRYQD
What are the official names of this protein?
Phospholipid phosphatase-related protein type 3, Inactive phospholipid phosphatase PLPPR3, Lipid phosphate phosphatase-related protein type 3, Plasticity-related gene 2 protein, PRG-2.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IEND3_NEUCR
Sequence: MYLSIIILPLLGSIVAGFFGRKVGVSGAQLITCLSVIITTGLAILAFFEVGFNNIPVTINLFRWIDSEWYNILWGFQFDSLTVAMLIPVLIISSLVHIYSISYMSHDPRGRVRGKRVYGDKLSNSGEVLKLKVPSCSWKTMSGWSNYSGTVTSLKMSENKMDNRGSKSVVIDSNSTVKEQRVDGSWSIKSHLMDLRCTLRGFERNRGIKLGFNLQQGWNSAKIPSKQFDFKKKFSTYNSTLRVNPWVWSGLIDGEGSFNIIVDRNKSRKLGWRAQLKFQLSLHTKDLNLLYLLQQYLGGIGSIHLARNRDIVNYSIDSIEDLNKLIIHLENYPLLTQKAADFFLFKQAVKLVNNKAHLTVEGLNQIVNIKASMNLGLSDTLKSEFAGYTPVERPVINCDNVFLDPYWISGFVSAEGNFDVRMPSTNSKLGYRVQLRFRISTLRVDIRLMEKIVEYFGSGKIYKYGGKSAVSLTIVDFTDITNILVPFFNKYPIIGIKLYDYLDWCKIHSLMINRSHLTVEGINSISLLLGRRR
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.
What are the official names of this protein?
Probable intron-encoded endonuclease 3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LAGLIDADG endonuclease family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PLSI_HUMAN
Sequence: MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILSVADSNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSTISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAGWHTISNFSQDIKDSRAYFHLLNQIAPKGGEDGPAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGNPKLNLAFVANLFNTYPCLHKPNNNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIRVPVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDEIIIKWVNQTLKSANKKTSISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNRIK
What is the function of this protein?
Actin-bundling protein.  In the inner ear, it is required for stereocilia formation.  Mediates liquid packing of actin filaments that is necessary for stereocilia to grow to their proper dimensions.
What are the official names of this protein?
Plastin-1, Intestine-specific plastin, I-plastin.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, stereocilium.
Protein: NFKB1_DROME
Sequence: MNMNQYYDLDNGKNVMFMNDASSTSGYSSSTSPNSTNRSFSPAHSPKTMELQTDFANLNLPGGNSPHQPPMANSPYQNQLLNNGGICQLGATNLINSTGVSFGVANVTSFGNMYMDHQYFVPAPATVPPSQNFGYHQNGLASDGDIKHVPQLRIVEQPVEKFRFRYKSEMHGTHGSLNGANSKRTPKTFPEVTLCNYDGPAVIRCSLFQTNLDSPHSHQLVVRKDDRDVCDPHDLHVSKERGYVAQFINMGIIHTAKKYIFEELCKKKQDRLVFQMNRRELSHKQLQELHQETEREAKDMNLNQVRLCFEAFKIEDNGAWVPLAPPVYSNAINNRKSAQTGELRIVRLSKPTGGVMGNDELILLVEKVSKKNIKVRFFEEDEDGETVWEAYAKFRESDVHHQYAIVCQTPPYKDKDVDREVNVYIELIRPSDDERSFPALPFRYKPRSVIVSRKRRRTGSSANSSSSGTESSNNSLDLPKTLGLAQPPNGLPNLSQHDQTISEEFGREKHLNEFIASEDFRKLIEHNSSDLEKICQLDMGELQHDGHNRAEVPSHRNRTIKCLDDLFEIYKQDRISPIKISHHKVEKWFIEHALNNYNRDTLLHEVISHKKDKLKLAIQTIQVMNYFNLKDVVNSTLNADGDSALHVACQQDRAHYIRPLLGMGCNPNLKNNAGNTPLHVAVKEEHLSCVESFLNGVPTVQLDLSLTNDDGLTPLHMAIRQNKYDVAKKLISYDRTSISVANTMDGNNALHMAVLEQSVELLVLILDAQNENLTDILQAQNAAGHTPLELAERKANDRVVQLLKNVYPEKGELAMTWIPCKVKEEIDSSSDESSDAGQLEIKSEEMDIETKDEDSVELDLSSGPRRQKDESSRDTEMDNNKLQLLLKNKFIYDRLCSLLNQPLGHGSDPQDRKWMQLARQTHLKQFAFIWLGAEDLLDHVKRKGASVEFSTFARALQAVDPQAYALLVNPT
What is the function of this protein?
Transcription factor that plays a key role in the humoral immune response as part of the peptidoglycan recognition protein (IMD) signaling pathway (PubMed:10619029, PubMed:8816802, PubMed:11269501, PubMed:11872802, PubMed:22022271, PubMed:29924997).  Rel-p68 subunit translocates to the nucleus where it binds to the promoter of the Cecropin A1 gene and probably other antimicrobial peptide genes (PubMed:11269501, PubMed:29924997).  I-kappa-B kinase complex (IKKbeta and key) and PGRP-LC are essential signaling components in transmitting the lipopolysaccharide (LPS) signal leading to cact degradation for NF-kappa-B (rel) activation (PubMed:11018014, PubMed:11872802).  Part of a Toll-related receptor pathway that functions in the apoptosis of unfit cells during cell competition (PubMed:25477468).  Also part of some antiviral immunity: activated downstream of Sting signaling, which detects double-stranded RNA (dsRNA) from viruses, and promotes expression of antiviral effector genes (PubMed:29934091, PubMed:30119996, PubMed:33262294, PubMed:34261127, PubMed:34261128).  May be part of a NF-kappa-B and Tollo signaling cascade that regulates development of the peripheral nervous system (PubMed:18000549).  Possibly post-transcriptionally regulates the neuron-specific genes sc and ase, by promoting the rapid turnover of their transcripts in the wing imaginal disk (PubMed:18000549).
What are the official names of this protein?
Nuclear factor NF-kappa-B p110 subunit, Rel-p110, Relish protein.
What are the subcellular locations of this protein?
[Nuclear factor NF-kappa-B p68 subunit]: Nucleus. SUBCELLULAR LOCATION: [Nuclear factor NF-kappa-B p110 subunit]: Cytoplasm. SUBCELLULAR LOCATION: [Nuclear factor NF-kappa-B p49 subunit]: Cytoplasm.
Protein: Y2876_SHESR
Sequence: MKPQWQQYIQIINQVVKPALGCTEPIAAAYAAAVARTLLPVEPESIAVQVSDNLYKNSMGVYVPGTGKIGLAIAAAAGALAGDAEAGLEVLANVTPEQVTKAQTLIDAGKVKVERTETDEFIYCCVSLTAGEQEAMVKICGGHTLIAEKRLNGELVFTADNAQAKATGSICDGIDINIESIYRFAQEVPFEEIQFILKASELNSKLSDEGMSKPYGLEVGRTMKNGIAAGIIGEDLLNKIVMLTAAASDARMGGANLPAMSNLGSGNQGIAATIPVVITAQCYKVSEEKLARALIMSHLGAIYIKSHYPPLSAFCGNTVTSAAASMAMVYLAGGSFEQSCYAIQNVISDSSGMVCDGAKASCAMKVSTSSSAAVRSFLMALSSQNVSGQGIIAKDVEKTIKNIGKMVLNGMSSTDVTIINIMSE
What are the official names of this protein?
UPF0597 protein Shewmr7_2876.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: YOHO_ECOUT
Sequence: MRIAKIGVIALFLFMALGGIGGVMLAGYTFILRAG
What are the official names of this protein?
UPF0387 membrane protein YohO.
What is the protein family that this protein belongs to?
Belongs to the UPF0387 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y321_MYCBP
Sequence: MRTEGDSWDITTSVGSTALFVATARALEAQKSDPLVVDPYAEAFCRAVGGSWADVLDGKLPDHKLKSTDFGEHFVNFQGARTKYFDEYFRRAAAAGARQVVILAAGLDSRAYRLPWPDGTTVFELDRPQVLDFKREVLASHGAQPRALRREIAVDLRDDWPQALRDSGFDAAAPSAWIAEGLLIYLPATAQERLFTGIDALAGRRSHVAVEDGAPMGPDEYAAKVEEERAAIAEGAEEHPFFQLVYNERCAPAAEWFGERGWTAVATLLNDYLEAVGRPVPGPESEAGPMFARNTLVSAARV
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase BCG_0321.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: URE1_ALIF1
Sequence: MAHISRTAYANMFGPTTGDRLRLADTELFLEVEKDFTTYGEEVKFGGGKVIRDGMGQSQVVNSECVDVVITNALILDHWGIVKADIGIKDGRIFGIGKAGNPDVQPNVDIVVGPATEVVAGEGKIITAGGVDTHIHFICPQQAEEGLTSGVTTFIGGGTGPVAGTNATTVTPGIWNMHRMLEAVDDLPINVGLFGKGCVSKPEALREQIEAGAMGLKIHEDWGATPAAIHNCLNVADEMDIQIAIHSDTLNEGGFYEETVKAIGDRVIHVFHTEGAGGGHAPDVIKSVGEPNILPASTNPTMPYTINTVDEHLDMLMVCHHLDPSIPEDVAFAESRIRRETIAAEDILHDMGAISVMSSDSQAMGRVGEVIIRTWQCANKMKLQRGILEGDNEHNDNERIKRYVAKYTINPAIAHGISHEVGSVEKGKLADLVLWNPAFFGVKPALVMKSGLVAYAPMGDINAAIPTPQPVHYRPMFACYGKAKFKSSMIFLSQASIEAGVPEKLNLQSQIGEVKGCRNISKKSMIHNSYTPNIELDSQTYEVKADGVPLVCEPATELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_BURCJ
Sequence: MRDETPEQPAPLRFGYTTGSCATATSLAAARLLLTGHADDAVEIVLPKGQRVMMRLEFCRTTADGAEAGTIKDAGDDPDVTHGALIFARVARAAAPGVRFHAGPGVGTVTRAGLTLPVGEPAINPVPRQMMTTHLEALAAEHGYAGGFDVTIGVEGGEALALKTMNPRLGIVGGLSILGTTGIVRPFSCSAYIASIHQGIDVARANGITHIAACTGNASEDAMRAHYQLPDMALIEMGDFAGAVLKHLRRAPVARLSMCGGFGKLSKLAAGHLDLHSRHSSIDLPLLAQWAAEAGASDALQAAMRAANTSQEALKLAQADAVPLGDLVCAHALQVARDIVPPSVAVEMFAIDRQGRFVGAAR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.