PharMolix/UniProtQA huggingface dataset:
Protein: COX2_STRPU
Sequence: MGTWAQFGLQDASSPLMEELTYFHDYALIVLTLITILVFYGLVSLLVSSNTNRFFFEGQELETIWTVIPALILILIALPSLQLLYLMDEVNDPFLTIKAFGHQWYWSYEYTDFNDLEFDSYMVPTSDVSFGNPRLLEVDNRLVLPMQNPIRVLVSSADVLHSWAVPSLGTKMDAVPGRLNQTTFFAARTGVFYGQCSEICGANHSFMPIVIESVPFNTFENWVTQYLEE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLNE_SALTI
Sequence: MTPLSSPLSQYWQTVVERLPEGFTETSLSAQAKSVLTFSDFALDSVIAHPEWLAELESASPQADEWRHYAGWLQEALAGVCDDASLMRELRLFRRRIMVRIAWAQTLSLVDDETILQQLSHLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALHLLPENDVAQLRVAYLFLRRLENLLQSINDEQTQTLPADDLNRARLAWGMKAENWPQLVGELTDHMANVRRVFNELIGDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQVLTLIADFRKELDKRPIGPRGRQVLDQLMPHLLADVCSREDAAVTLSRITPLLAGIVTRTTYLELLSEFPGALKHLIMLCAASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELRQYLLRVPEEDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWTQMVARYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEAWTWEHQALVRARVVYGDPQLTSQFDAVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDNVRILELLAQNGIMDEHEAQALTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: RSGA_BACCN
Sequence: MPEGKIIKALSGFYYVQHEEGITQCRGRGVFRKNKITPLVGDQVVFQAENQNEGYVLEVFERKNELVRPPIANVDQAILVFSAVEPDFNPGLLDRFLVLIEYHNIKPIICISKMDLVDEPMRKMVESYANDYREMGYAVLFTSVHAAESIEILKPFLEECVSVVAGQSGVGKSSMLNVLRPDLELKTNDISSHLGRGKHTTRHVELISIGSGLVADTPGFSSLDFIDIEVEDLTFCFPELKEESQYCKFRGCTHLSEPKCAVKAAVEEGRIADYRYEHYKQFVEEIRERKPRY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA_PSECP
Sequence: MTQQFYVSPEQLMKDRADFARKGIARGKSVVVISCEDGIALVAENPSPSLHKIGEIYDKIAFAAVGKYNEFESLRQAGVRYADVRGYSYDREDVTARGLASVYAQSLGAVFTAEQKPFEVELAVAEVGATQAEDHLYRLTFDGSIADEHSFVVMGGQADRVASAIDQGWRASLGFPDAVRLALNGLAPAPETEETAKPVPARAIEVAVLDRHSEEVRGARRAFRRLNDADITALLA
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_SALPC
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFSEGYTLTTNNRMELMAAIVALEALKEHCEVTLSTDSQYVRQGITQWIHNWKKRGWKTAEKKPVKNVDLWKRLDAALGQHQIKWVWVKGHAGHPENERCDELARAAAMHPTQEDSGYQAEA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T3RE_BPP1
Sequence: MSKGFTFEKNLPHQKAGVDAVMNVFVSATSHQEDNVSIRLLVNPELRLTEQQYYKNIKKVQELNGIEHVKNNYDARSNVIDVSMETGTGKTYTYTKTIFDLNKSFGINKFIIIVPTLSIKAGTVNFLKSDALKEHFRDDYEREIKTYVVESQKNAGKSTKSYMPQAIHDFVEASNFNKKYIHVLVINTGMIHSKNLNSTYDVGLLDNHFDSPFSALGAVKPFIIIDEPHKFPTGKKTWENIEKFNAQYIIRYGATFSEGYKNLVYRLTAVDAFNEDLVKGIDAYIEDIVGDGDANLKFIKSDGEEVTFELNENNKKTLFKLTKGESLSKTHSAIHDLTLDALGKNTVVLSNGIELKIGCSINPYSYDQTLADSMMRKAIKEHFKLEKEFLTQRPRIKPLTLFFIDDIEGYRDGNNIAGSLKAKFEEYVLAEANELLKIEKDEFYSNYLEKTVKDISSVHGGYFSKDNSDKDDKIEKEINEILHDKELLLSLDNPRRFIFSKWTLREGWDNPNVFQICKLRSSGSTTSKLQEVGRGLRLPVNEYMCRVKDRNFTLKYYVDFTEKDFVDSLVKEVNESSFKERVPSKFTQELKEQIRAQYPELSSRALMNELFNDEIIDDNDNFKDSDAYSRLKSKYPAAFPIGVKPGKIKKATDGKRRTKMRVGKFSELKELWELINQKAVIEYKINSENEFLSIFKSFMLEETERFTKSGVHTRIDKIYIHNDMAMSKSIVSDDDDFAKLNTMSYREFLDNLSQTIFVKHDTLHKVFCDIKDTINITEYLNIQTIRKIKSGFSKYLLNNSFNKFSLGYNLISGSIHPTKFTNADGKPLDEVLSSDLGVLQDNSKAPLDTYLFEEVFYDSELERRNITDREIQSVVVFSKIPKNSIKIPVAGGYTYSPDFAYVVKTAEGDYLNFIIETKNVDSKDSLRLEEKKKIEHAQALFNQISQSVKVEFKTQFANDDIYQLIKSALP
What is the function of this protein?
A type III restriction enzyme that recognizes 2 inversely oriented double-stranded sequences 5'-AGACC-3' and cleaves DNA 25-27 base pairs downstream of one site, producing a single-strand 5' protrusion of two nucleotides.  DNA restriction requires both the Res and Mod subunits (PubMed:2837577, PubMed:11178902).  DNA topology affects its action; relaxed and negatively supercoiled DNA are digested but positively supercoiled DNA is not a good substrate (PubMed:11178902).  After binding to one recognition site undergoes random one-dimensional diffusion along DNA until it collides with a stationary enzyme bound to the second DNA site, which is when DNA cleavage occurs (By similarity).
What are the official names of this protein?
Type III restriction-modification enzyme EcoPI Res subunit, Type III restriction enzyme EcoPI.
What is the protein family that this protein belongs to?
Belongs to the type III restriction-modification system Res protein family.
Protein: RS5_CHLPD
Sequence: MAKTSARSIKPGELNLKEKLVHINRTAKVVKGGKRFGFNAIIVVGDKEGHVGYGLGKANEVQDAIAKGVEDGKKNVIKVPIVKGTIPHQIIAKYGSAKVLMKPATPGTGLIAGGAVRAVLEMAGIHDVLTKSLGSSNPHNVVKAAIKGLQSMSDAYEVGERRSKSLKEVFES
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: TIG_BEII9
Sequence: MQVTETLSQGLKREYKVVLPAADIASRLDEQLQEMKAKVRINGFRPGKVPVAHLKRLYGRSVMLDVVQEAVNEANRKILEENNLRPAGEPRIDFDGEKEDMEKAFESTADFAFKVALEILPKFEIGGFEDIAIERFVADVPEEEVERILGRFADQNRAYEPRAEGAAAEKGDKVTIDFVGKIDGEPFEGGSGEDIDLVLGSESFIPGFEDQVIGLKVGEQRQIAVTFPEDYAAKLAGKAATFDVTVKQVAAPGEQTIDDELAKAFGYETLEAMKEQIRTTISDEYAAASRAQWKRALLDELDKKYQFELPEGLVENEFATVWRKVELDQQRSGKTFEEEGTTEEAARADYRKIAERRVRLGLLLAEIGEKAGIVVPDEEVGKALVERARAFPGQEKMIWDFYRQNPKALNEIRAPLFEDKTVDYILTQAKVTDTKVSKDELLKKAQEAEESEPAEEAVSE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: THIM_HELPJ
Sequence: MLKELRQKRPLVHNITNYVVAQFVANGLLALGVSPLMSDAIAEMPDLAKISDALAINIGTLNERTILCAKEAIKRYKALNKPIVLDPVGCSASALRYDTSLELLESKGISTLRGNAAELGSLVGISCESKGLDSKHSATPIEIVKRAAQKYSVIAVMTGKTDYVSDGKKVLSITGGSEYLAAITGAGCLHAAACASFLSLKKDPLDSMVQLCAFYKQAAFSAQKKALENNGSNGSFLFYFLDALSLPIELENSLIKEEL
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: NAL4B_MOUSE
Sequence: MASLFSDFGFIWYWKELNKIEFMYFKELLIHEILQMGLKQISWTEVKEASREDLAILLVKHCDGNQAWDTTFRVFQMIGRNVITNRATGEIAAHSTIYRAHLKEKLTHDCSRKFNISIQNFFQDEYDHLENLLVPNGTENNPKMVVLQGVAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCHDVKQLQTASLADLISREWPSPSAPMEEILSQPEKLLFIIDSLEGMEWNVTQQDSQLCYNCMEKQPVNVLLSSLLRKKILPESSLLISTSCETFKDLKDWIEYTNVRTITGFKENNINMCFHSLFQDRNIAQEAFSLIRENEQLFTVCQAPVVCYMVATCLKNEIESGKDPVSICRRTTSLYTTHILNLFIPHNAQNPSNNSEDLLDNLCFLAVEGMWTDISVFNEEALRRNGIMDSDIPTLLDIGILEQSRESENSYIFLHPSVQEFCAAMFYLLHSEMDHSCQGVYFIETFLFTFLNKIKKQWVFLGCFFFGLLHETEQEKLEAFFGYHLSKELRRQLFLWLELLLDTLHPDVKKINTMKFFYCLFEMEEEVFVQSAMNCREQIDVVVKGYSDFIVAAYCLSHGSALTDFSISAQNVLNEELGQRGKLLILWHQICSVFLRNKDIKTLRIEDTIFNEPVFKIFYSYLKNSSCILKTLVAYNVSFLCDKRLFLELIQSYNLEELYLRGTFLSHSDVEMLCDILNQAECNIRILDLANCSLCEHSWDYLSDVLRQNKSLRYLNISYNNLKDEGLKALCRALTLPNSALHSLSLEACQLTGACCKDLASTFTRYKCLRRINLAKNSLGFSGLFVLCKAMKDQTCTLYELKLRMADFDSDSQEFLLSEMERNKILSIENGV
What is the function of this protein?
May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 4B, NALP-gamma.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
Protein: DNLJ1_DESVV
Sequence: MCNIPQHQSRAAWLRAELARHNRLYYELDTPEISDAEYDTLYRELVNLETLWPALMDEASPTQRVGGEVLDRLEKQAHTMRMYSLDNAFSRDEWGAFIQRMYNTLPETPSSFWCDPKMDGLALEVIYENGVFTSALTRGNGAEGEVVTAAMRTVRNLPLRLRGNNVPHRLEVRGEVVIAKADFEQLNARQSAVGGKVFANPRNAAAGSVRQLDTSITAGRPLQFLAYGVGQVVLDGGTAPWTTHSDLMARLREWGFDSPPEGRLCTSPDEVWAYYEMLGARRESLAIEIDGVVAKVDDTEAQEALGFTARAPRWALALKFPAMQVRTRLQDIRVQVGRTGVLTPVAILEPVRVGGVEVSRATLHNAYEIEDKGLMLGDMVLVQRAGDVIPEVVRPLVEDRTGGERPFVFPTTCPECGSVVHKPNDEVAHRCINVSCPAVRRQSIIHFVSKAGLDVRGFGEHIVQQLVDAGRVTTAADLFSLTTVDLMGFERMGPTSAANAIASLDAARTGATLARLICALGIRHVGEQTARTLATHFVDLDAMRKADGEKLLHLPDIGPEVAASIRCFFDNQSNIELLEQLRDKGLWPRKPDANGPFVREGSQLQGLKLLFTGSLQRMSRSEAKRMAEAAGAHVVSNVSKSLDMIVAGADAGSKLDQAKSLGLHVIDEDAFANLLKGLDR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase 1, Polydeoxyribonucleotide synthase [NAD(+)] 1.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: Y1586_CROS8
Sequence: MPTVNPQQLADRIDTVLDILVAGDYHSAIHNLEILKAELLAQSQQNDEPGEKKQKAPWEI
What are the official names of this protein?
UPF0509 protein ESA_01586.
What is the protein family that this protein belongs to?
Belongs to the UPF0509 family.
Protein: Y2146_YERPY
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDPGANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDEDNNMETIIYEGYGPGGTAVMVECLSDNRNRTVSEVRHAFTKTGGNLGTDGSVSYLFTKKGVISYAPGLEEDTVMDAALEAGADDIVVYDDGAIDVFTAWESLGAVKDVLDATGLVAEGAEVSLIPSTKAELDAETAPKLLRLIDMLEDSDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein YPK_2146.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_THESM
Sequence: MDYKQFFSNFRYLSSSKGIGGKIKSKPEDFIVREVIPRSVFRSDQCLIYLIKKQNWETMAAIKEIAKRIGIDYKNVGFAGTKDRHAITYQYISICSENLESIKESIASLNIEGISLKFVGRGKPLKLGMLIGNHFQIILRGLEDPERALERTKKILKELKLKGGFPNYFGSQRFGERRVINHEVGKLLLKGDFEGAALKFLGEYTGDMTGDEARKDFLKTGDVEKALEEFPNFLRYERAMLYKYRETRSWKKAFAVLPRPIVRIFIHSYQSYLFNKALSRRIEEGLSLNEALSGDIVCQVKKGLPIRNKTFKVTERSLKFVNERVKRGEAMVTGPVFGFASRLADGPMGKIEREILDEEGIDLNGFKMKQLPILAEAGGRRELLIKPRGFKYKSSEEGLIFRFFLPKGVYATSVMREIMKDH
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: MURC_RUTMC
Sequence: MKDLRMVFKSRMNNIHFVGIGGSGMSGIAEVLHNLNYSVSGSDISQNKITDRLEKMGCQIYHKHHQDNIKNAQVIVVSSAIKDNNLEVIKAHQLNIPVVPRAEMLAELMRFRFGIAIAGTHGKTTTTSIITHILNVAELDPTYIIGGILNSSGINAKLGESDYLIAEADESDASFLHLQPMLSVITNIDYDHMVTYDNDYQNLKDAFIKFSANLPFYGACIMCADDEGVNEILNSIHRPLITYGFNNGTDIQAVNVKQVGMQMYFDVIYDKYTKQIPIKLNLIGKHNILNTLAAIGICCELNIKTNIIQKALANFSGVARRLDHHGKLNINNAQVSLFDDYAHHPKEISAVFESLKNTYQDKRLVVIFQPHRYSRTRDLFDDFVYTLSSADILILLNIYPAQEKPIAHINSSTLANAIRRSSGLNPMVIKNPKEILTVLPSIVNNNDILLILGAGDIHILPDLLKSNYI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_STRGG
Sequence: MAKVRVYELAKEFGVESKVVMAKLQELGEFVRSASSTIEAPVVRKLTDALQGPGGNAGKSAAKPGAPRKAAPAKPAAPSPAAAARPAAPKPGAPAPKPAEAPSSTPAAPSAPSAGPRPGPKPAPKAAPVTPVPAAEFSAPAPAQPAAPQPQAPRPAGATPGPRPTPARPAPAGGQRDGGRDGGQRDGGRGGERGGDRPARPAGQGAPRPGGARPAGPRPGNNPFTSGGSTGMARPSAPRPGGAPRPGGGQERPGAPRPQGSGPGGAPRPQGGQGQGGARPTPGGMPRPQAPRPGGGPAGNRPNPGMMPQRPAAGPRPGPGGGGRGPGGGGRPGAGGGGRPGGGGFAGRPGGGGGGGFAGRPAGPGGGGGAGRPGGGGGFGGRPGFGGRPGGPGGRGGTQGAFGRPGGPARRGRKSKRQRRQEYEAMQAPSVGGVMLPRGNGQAVRLSRGASLTDFAEKINANPASLVAVMMNLGEMVTATQSVSDETLRLLAEEMNYVLEIVSPEEEDRELLESFDIEFGEDEGGEEALVSRPPVVTVMGHVDHGKTRLLDAIRKTNVVAGEAGGITQHIGAYQVSSEVNGEDRKITFIDTPGHEAFTAMRARGAKSTDIAILVVAANDGVMPQTIEALNHAKAAEVPIVVAVNKIDVEGADPTKVRGQLTEFGLVAEEYGGDTMFVDISAKQGLNIEALLEAVVLTADASLDLRANPEQDAQGIAIESHLDRGRGAVSTVLVQRGTLRIGDTVVVGDAYGRVRAMLDDNGQNVQEAGPSTPVLVLGLTNVPGAGDNLLVVDEDRTARQIAEKRAARERNANFARKGVRFSLENLDEALKAGLVQELNLIIKGDASGSVEALESSLLQLDVGEEVDIRILHRGVGAVTESDINLATGSDAIVIGFNVRAAGRAEQMAEREGVDVRYYSVIYQAIEEIEAALKGLLKPEYEEVELGTAEIREIFRSSKLGNIAGVLVRSGEVKRNTKARLLRDGKVIAENLNISGLRRFKDDVTEIREGFEGGINLGNFNDIKIDDVIATYEMREKPRG
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_STRT1
Sequence: MKVSIVGITGYSGLELVKILNNHKKVELVSIHATKEVGRRLSDVYPYLAGVCDLKIEDFDAQEIIEKADLVFFATPSGVASSLAEEFVQADFPIIDLSGDHRLPADVYQEWYKKSPAKKMILNKFTYALSEYTDVKGKKFIANPGCYATATELALIPLVAAGLIETDSIIVDAKSGLTGAGKALSESSHFVNVHDNYMTYKLNHHQHIPEIVQTLQAFDADMPEIQFSTSLLPVNRGIMATVYCKLKKDVAVSDIASAFAKAYDDKPFVRVQENLPELHNVIGSNFTDIGFAYNEKTNVMTVISVIDNLLKGASGQAVQNLNLMQGWDETEGLHMTPSYL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_BORBR
Sequence: MIPGEILTEPGQIELNVGRPTLTIAVVNEGDRPIQVGSHYHFAEANNALVFDRELATGYRLNIPAGNAVRFEPGMRRTVELVAVGGERRIFGFQGKVMGALK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLTA_BACVZ
Sequence: MKLLDAIKTYADAKPQAEAFRSLDHSLTYGELWDLSERVASGIQKHTADGSKAPVLVYGHMEPNMIVSFLGSVKAGRPYIPVDVSIPAERIVKIIESSGAELLISVSGDAVDTGSNLIKTVTPEELAADGDADLSRENWVKELDTFYIIYTSGSTGNPKGVQISADNLQSFTDWICRDFPVGEGKTFLNQAPFSFDLSVMDIFPSLQTGGTLHCVTKDKINKPKVLFEELEKSKLNVWTSTPSFVQMCLMDPGFTQELLPEAEVFMFCGEALPAAVAQELLNRFPKARVFNTYGPTETTVAVTSVEITQQIIDENESLPVGFAKPDMDIFIMDENGNKLPDGEKGEIIIAGPSVSKGYLGEPSLTEKAFFPIDGQWAYHTGDAGYVQDGQIFCQGRLDFQIKLHGYRMELEEIEVHVRQSQYVRTAVVIPYQPNGPVEYLIAAIVPEKHDFEKEFQLTSAIKKELAASLPAYMIPRKFIYQDHIQMTANGKIDRKRIGEEVLV
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_AGRRK
Sequence: MARIAGVNIPTAKRVVIALRYIHGIGPKFAQEICEKVGIPAERRVNQLTDAEVLQIRETIDRDYQVEGDLRRETSMNIKRLMDLGSYRGLRHRRSLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: YN03_CAEEL
Sequence: MPPPPLISLDVEGVYFKTRIATLKSIEGTYFTKLFETNWREQLDRDGRLFIDRDSSVFPVILNFLRDHEKCSLPKDEYQLMRILREAVFFKIGPLRNMIEHKLRTFCTCPPELPSTPIPNQILTQKENVPIVPRNLLLSKPPPPPPPPLPSLMQPKDTVQIPMRKPPTGRNSKKIKTSADSISLPRNFTHIAHVGWNGASVLFDKKMTDDPTVRKICDAAAEAVDLSAVYNVVNKNADEESHSVEVLITGGLMQSRDGTSRH
What are the official names of this protein?
Uncharacterized protein T23G5.3.
Protein: NTA1_SCHPO
Sequence: MKFGCVQFFPKLGKVNENIVHLRQLLDQHSEALQSVKLLVFPEMCLTGYNFKNSESIQPFLENVTSNHCPSIQFAQEVSEQYRCYTIIGFPEFQNSNGISTLYNSTALISPKKELLNVYHKHFLFETDKSWATEGKGFSFEPCIPELGPISMAICMDINPYDFKAPFEKFEYANFILRELEHQQMVSSNVSRPIICLSMAWLVSDDKVIDASLPDIKNLHYWTTRLSPLINSNTDAIVLVANRWGKENDLNFSGTSCIMELSQGRAILHGVLKAAENGIVVGELEK
What is the function of this protein?
Deamidates N-terminal Asn and Gln.  Component of a targeting complex in the N-end rule pathway (By similarity).
What are the official names of this protein?
Protein N-terminal amidase, NT-amidase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SSRP_SALTO
Sequence: MPREKGRKVVASNRKARHDYSILDTYEAGMALTGTEVKSLRAGRASLVDAFAQERNGELYLHGMHIPEYVQGTWTNHEPRRTRKLLLNRIEIDRLIGKTRESGLTIVPLQVYFSDGWAKVEIGVAKGKKSYDKRQDLAKRDAQREIARAAGRRGKGMAD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: BH070_ARATH
Sequence: MFVLRVSNQSFKLHQQVQCKDEIFCLDQKVNVRRSLQVQETVEDHQSFALEEEEQQLSTPSLLQDTTIPFLQMLQQSEDPSPFLSFKDPSFLALLSLQTLEKPWELENYLPHEVPEFHSPIHSETNHYYHNPSLEGVNEAISNQELPFNPLENARSRRKRKNNNLASLMTREKRKRRRTKPTKNIEEIESQRMTHIAVERNRRRQMNVHLNSLRSIIPSSYIQRGDQASIVGGAIDFVKILEQQLQSLEAQKRSQQSDDNKEQIPEDNSLRNISSNKLRASNKEEQSSKLKIEATVIESHVNLKIQCTRKQGQLLRSIILLEKLRFTVLHLNITSPTNTSVSYSFNLKMEDECNLGSADEITAAIRQIFDS
What are the official names of this protein?
Transcription factor bHLH70, Basic helix-loop-helix protein 70, AtbHLH70, bHLH 70, Transcription factor EN 13, bHLH transcription factor bHLH070.
What are the subcellular locations of this protein?
Nucleus.
Protein: DGTL1_ALIF1
Sequence: MNKTNEITLSPHWEDRISNEQKLRRNDQRSVFQRDRARILHSAAFRRLQAKTQVHGPGSANDFYRTRLTHSLEVSQIGTGVVAQLKLRQPEFRALLTSTSLMESICLAHDIGHPPFGHGGEIALNYMMRDHGGFEGNGQTLRILSKLEPYTEHFGMNLARRTLLGVLKYPAFLDQVHSTERPQEVTNVRHLKSIDWHPPKGVYRDDADILNWILKPLSDVDKALFSTFRFQQDSQNTHRKTRFKSIDCSIMELADDIAYGVHDLEDAIVMGIVTRNQWQESVASKLAECGDEWFEANIETISDKLFSGLQYQRKDGIGSIVNALLTSITIKPTTFNDEAEFESELLRWNAFLSPSMSYALEVLKKFVGQFVIHNSEMQRIEYKGQQIVMEIFDALNSDPERLLPENDKREWREAKESGANAHRVIADYIAGMTDGYAQRLYNQLFVPI
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.