PharMolix/UniProtQA huggingface dataset:
Protein: LOLD_SHIBS
Sequence: MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSCALEMLKAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRDGRLTAELSLMGAE
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PHT18_ARATH
Sequence: MPIKVLSSLDVARTQWYHFKAIIVAGMGLFTDAYDLFCIAPVMKMISHVYYNGDSINTAVLSTSYAIALLGTATGQLVFGYLGDRVGRRRVYGLCLIIMILSSFGCGFSVCTTRRSCVMVSLGFFRFFLGLGIGGDYPLSATIMSEFANKRTRGAFIAAVFSMQGLGILVSSAVTMAVCVAFKRSGGGLEVDAAAPTEADLAWRLILMIGALPAALTFYWRMLMPETARYTALVENNIVQAAKDMQRVMSRSHISDEATTDPPPPPPPPSYKLFSRCFFRLHGRDLFAASFNWFLVDIVFYTSNLLLSHIFSHYSKKPSTAENVYDAAFEVAELGAIIAACSTIPGYWFTVYFIDKIGRVKIQIMGFFFMAVIYLVAGIPYSWYWSKHEHNNKGFMVLYGLVFFFCNFGPNTTTFIIPAEHFPARFRSTCHGISGAAGKLGAIVGTVGFLWATKKMESDDKNQIYPEVNRMRIAFLILGGVCIAGILVTYFFTKETMGRSLEENEHDQDNNAESEDEPQIVDGQSSVSTLLQTR
What is the function of this protein?
High-affinity transporter for external inorganic phosphate.
What are the official names of this protein?
Probable inorganic phosphate transporter 1-8, AtPht1;8, H(+)/Pi cotransporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SIX6_HUMAN
Sequence: MFQLPILNFSPQQVAGVCETLEESGDVERLGRFLWSLPVAPAACEALNKNESVLRARAIVAFHGGNYRELYHILENHKFTKESHAKLQALWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRHLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQQQVLSQGSGRALRAEGDGTPEVLGVATSPAASLSSKAATSAISITSSDSECDI
What is the function of this protein?
May be involved in eye development.
What are the official names of this protein?
Homeobox protein SIX6, Homeodomain protein OPTX2, Optic homeobox 2, Sine oculis homeobox homolog 6.
What is the protein family that this protein belongs to?
Belongs to the SIX/Sine oculis homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HAP2_SCHPO
Sequence: MNPYEPVEGLYVNAKQYHRILKRREARAKLEERLRGVQTTKKPYLHESRHKHAMRRPRGPGGRFLTADKVSKLRAQEAAEAAANGGSTGDDVNATNANDATVPATVSSEVTHTSEGYADSNDSRPSSISNSSESPAPINSATASMSPANNTSGNNITSPNVRGELDMSGNIAMSGGPTNTASTSGPVPHDMTVLPQTDSNTSNLMSSGSQLGSFATASTNGNNSTTTTTSSAAHPGSFHKGTNDYSSTLAGNEHSAFPGLDVYHDDSVSAGAAFIPHNPMDSIDHLDVNDPTATGLPVLPASDIDPLNLTGNTQDSMIIGQQTYPSHGSSGTMK
What is the function of this protein?
Global regulator of respiratory functions in yeast cells.  It belongs to a complex that binds to the sequence CCAAT located upstream of genes involved in mitochondrial electron transport.
What are the official names of this protein?
Transcriptional activator hap2.
What is the protein family that this protein belongs to?
Belongs to the NFYA/HAP2 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URED_SHEHH
Sequence: MNIPESVSYKRPESHFGWRAELSLKYGIKREKTRLLERHQLGPLTVQKTFYPEGAACHTYLLHPPGGVVGGDQLSFNIDVGTQAHALLTTPGATKFYRSNGEQAWQSQELTVAKDGLLEWLPMENIFFPGANCKLLTQVNLATNARFIGWEMQCFGRPMLAETFDNGQVLGQTFIHRDHRVLLAETLRVKSQSHIDQAAALRNFAMSGSLYITPIEPELIDKINQVIDEQQLRFGSEILLGSSEIGSASTSSAMSLTSTAEDSLIVVRALGQQTEPMMASFVQIWRCVRLHWFGELPEVPRIWST
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UDG8_ECOLX
Sequence: MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSPIVDKEIEEYLATKDLNFRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMVIKSTIPVGFTKSIKERLGIDNLIFSPEFLREGKALYDNLHPSRIVIGERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD
What are the official names of this protein?
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: RS4_STAAM
Sequence: MARFRGSNWKKSRRLGISLSGTGKELEKRPYAPGQHGPNQRKKLSEYGLQLREKQKLRYLYGMTERQFRNTFDIAGKKFGVHGENFMILLASRLDAVVYSLGLARTRRQARQLVNHGHILVDGKRVDIPSYSVKPGQTISVREKSQKLNIIVESVEINNFVPEYLNFDADSLTGTFVRLPERSELPAEINEQLIVEYYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RSMG_COXB1
Sequence: MTEKLKQGIDQLGLKVPETIQQSMLAFLAFLQKWNQAYNLTAITEIKSMITHHLLDSLSILPYLKGDKILDVGSGAGFPGIPLAFACPEKKFTLIDSKAKKTAFLLQAASRFKITNVTIIQERVGSYQPGFYFDTITCRALGSVREIMEQTNHLLRPGGQWSIMKGTYPEKELRGTDASAIVHVLNVPGLKAERHLVEVKNNKG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_ECOSE
Sequence: MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADPTAMVVATVDEHAQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: TOLB_ERWT9
Sequence: MKQAFRVALSVLMLFVAVAHAEVRIEITQGVNTARPIGVVPFKWDGPGAAPEDIGGIVAADLRNSGKFNPIDRARLPQQPTSVAEVQPAAWTALGIDAVVVGQVQPGADGSYTVSYQLVDTSGNPGAVLAQNQFKVTKQWLRYAAHSASDESFEKLTAIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKVAYVTFESGKSALVIQTLANGAIRQVASFPRHNGAPSFSPDGSKLAFALSKTGSLNIYVMDIGSGQISQITDGRYNSTEPTWFPDSQSLAYTSDQAGRPQIYKIGVNGGTAQRITWEGAQNQDADVSSDGKSMVMISTNSGAQHVARQDLVTGAVQKLTDTFLDETPSLAPNGTMVIYSSTQGMGSVLQLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DXR_SHEB5
Sequence: MQNMVILGATGSIGASTLSVISANPFAYSVYGLVANASVDKMLALCVAHKPKVAHMVDEAAAKQLRAVLPATLNIQVTTGMNDLLGLVTAAEVDTVMAAIVGAAGLVPTLEAVKAGKRVLLANKEALVMSGELFIEATKRSGAVLLPVDSEHNAIFQCLPQEVQANLGRCDLAASGISHILLTGSGGPFLRSDLATLAAMTPAQACKHPNWSMGPKISVDSATMMNKGLEFIEARWLFNTQAEQLKVVIHPQSVIHSMVQYRDGSVIAQMGNPDMRTPIAHCMAYPQRIHSGVEPLDFFKVGQLSFYEPDFERFPCLALAMDACAQGQEATTVLNAANEIAVEAFLQGQIGFTQIAKVNEACLVTVPKCPMGSIEDILALDAQTRVYARETLASIA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MTFA_SHIBS
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAERFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN3_SCHPO
Sequence: MVANMEFQGTLPFHPLEDPETLLLKFTDFVHQHSVEQCNQLSMYIIASVNSLAEAFYGSHPEKYNIVFQSVEYAAHSPAISVMHVCYLKELLRQGQYATSLKSFNDLEVSKHIPGSILLQYCMYAAYHCLGNNDLDSAKVWYFSILYIPTTTLTSFHEEAYYSFLLLYIITTGKKFQLDSATSSNVLPLKRHMVPYEEFLDAYLKDVNTLRTVIKEHWSRFLKDNSTAFILFALEVYPMHRLKKWRKTFSSLKLEYIAKQLAISQDVAKEIIQKFDNKTNFTVANGEIFLTFNALDDVSPEMHSDLCQQLIEASKNFEASIRLKSVIYSKIMAKKLNA
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
What are the official names of this protein?
COP9 signalosome complex subunit 3, CSN complex subunit 3, SGN3.
What is the protein family that this protein belongs to?
Belongs to the CSN3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CATC_SCHMA
Sequence: MHWVFHCILIILACLRFTCADTPANCTYEDAHGRWKFHIGDYQSKCPEKLNSKQSVVISLLYPDIAIDEFGNRGHWTLIYNQGFEVTINHRKWLVIFAYKSNGEFNCHKSMPMWTHDTLIDSGSVCSGKIGVHDKFHINKLFGSKSFGRTLYHINPSFVGKINAHQKSWRGEIYPELSKYTIDELRNRAGGVKSMVTRPSVLNRKTPSKELISLTGNLPLEFDWTSPPDGSRSPVTPIRNQGICGSCYASPSAAALEARIRLVSNFSEQPILSPQTVVDCSPYSEGCNGGFPFLIAGKYGEDFGLPQKIVIPYTGEDTGKCTVSKNCTRYYTTDYSYIGGYYGATNEKLMQLELISNGPFPVGFEVYEDFQFYKEGIYHHTTVQTDHYNFNPFELTNHAVLLVGYGVDKLSGEPYWKVKNSWGVEWGEQGYFRILRGTDECGVESLGVRFDPVL
What is the function of this protein?
Thiol protease.  Has a role as a digestive enzyme.
What are the official names of this protein?
Cathepsin C.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: THIG_BRUSU
Sequence: MLEFYGKRFESRLLLGTAQYPSPSILADAVRASLSRIVTVSLRRESGEARAGQDFWALIKALGVAVLPNTAGCHTPREAITTAHMAREVFGTNWIKLEVIGDTDTLQPDPFGLVEAARILCDESFEVFPYMNDDLIVAERLIEAGCKVLMPWGAPIGSGRGLNNPYALKTMRAHFPDIPLVVDAGIGVPSHAAAAMELGFDAVLINTAVAKAGDPAAMARAFALAVEAGRLAYEADPIEARDMASPSTPLLGKAFL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIB_BURMA
Sequence: MRIFRFVKIVFTVIRFGLDEVMLSRIENPRVKLLLRITTIGRRFADPPAVRLRRALESLGPIFVKFGQVLSTRRDLLPVDFANELAKLQDQVPPFDSAVAIAIVEKSLGARIDVLFDEFERVPVASASIAQVHFAKLKQGEHKGKAVAVKVLRPNMLPVIDSDLALMRDIATWAERLWADGRRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMFWDYSTPAVLVMERMTGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPKHFGRYIALDFGIVGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPPDTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMTEQIGLRGWYERFKVEAPQWSKTLPQLPRLVHQALISHHEAPRAISDDLIRQILVEQRRTNRLLQALLVFGLAVGAGAVIARVLIVLAYGG
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FUMC_SYNY3
Sequence: MVNSHRLETDSMGSLEVQADRLWGAQTQRSLMFFDIGSDVMPPDLIRAFAILKKAAAITNQDLGKLPADKAELIITAADEIIAGQWLDHFPLRIWQTGSGTQTNMNVNEVIANRAIAICGGELGSKNPIHPNDHVNMSQSSNDTFPTAMHIAAVAGLQTKLIPSLQALRDSLNEKAECFAGITKIGRTHLMDAVPLTLGQEFSGYVAQLDQGLTQINYCLPGLLELALGGTAVGTGLNSHPQFAKKVAEEIAQLTGYTFISAPNKFAALAGHEAIAFASGVLKSIAASLMKIANDLRWMGSGPRCGLGELALPANEPGSSIMPGKVNPTQCEAMTMVCVQVMGNDATIGFAASQGNFELNVFKPVIIHNFLHSLHLLSDACASFRQHLVVGLQVNESKVKDFLDTSLMLVTALNPHIGYDNAALVAKTAFAQGITLKQAAVDLGLLTPAQFDAWVVPEQMIAPIAD
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1058_MYCA1
Sequence: MTRSEGDTWNLASSVGATATMVAAARAAATRRPRPVLTDEYAEPLVRAVGLDVFTKLASGELDPDDLERDVGFARMVDTFAARGRFYDDYFAAAGKAGLRQVVIVASGLDARPYRLSWPAGTTVYEIDQPEVIAFKTATLSRIGAAPTAELRTIGIDLRQDWPAALQDAGFDAAQPTAWLAEGVLIGFLPPEAEVRLLDSITPLSAEGSRFAADYGSLNDASQASTEQARRTTEGWRRRGLDMDIAALTYPGKHTDVAAHLGADGWATTTFGLADLFAAAGLPELTEAEQGPAATLSFVRAIKS
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_1058.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: UVRC_LEIXX
Sequence: MADTVSYRPKAGEIPTQPGVYRFRDKTRRVLYVGKAKNLRARLSNYFQPLRSLHERTRRMVTTAASVEWTVVGSEFEALQLEYTWIKEYNPPFNVQFRDDKSYPYLAVTLGERIPRVLVTRNRIAKGARYFGPYTKVWAIRDTVDLMLKAFPVRSCSDGVYRRAELTGRPCLLGDIGKCAGPCVGRVTPEEHRRLAEDFVSFMAGDDSKHIRDLTEKMKQAAGTMDYEAAARHRDAIQALEAAMGKSAVVLQDNVDLDAFGIGHDELAAAVQQFIVRGGRIRGVRSWVVDKELDVELGELIETVMQNAYEGADAPPREILVPVLPDDAAELGQWLTGRRHENSGGGVSDPAATRGRLSGRVELKVAQRGDKAALAQTAEMNAKNALILYKTRRSSDFVARSKAFSDIQDALGMEDAPLRMECYDVSHLSRTNIVASMVVFEDGLPRKDQYRRFSIPESADDTESIYQVISRRLAYLRKEPPVEALTPANGHDLATDLDAEAVEAAERRRKKFAYPPNLLIVDGGQPQVAAARRALEESGVSGVHLAGIAKRLEEVWLPGSDFPVILPRNSDALFLIQRIRDEAHRFAITYQRSRRKRDITTVLGEIPGLGPARVKELLKHFGSVAQLRKAAPEEIAEVRGVGLRLAAAVFERLADR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTF2_ALKEH
Sequence: MRTWIAILAVVLVLLLNACTDGPEDGPRLEHPDETGVLRVVTRNSATTYYLDRHERAVGPEVALVEAFADHRGWTVDWTVAATTAEVLDYLEAGAAHLAAAGLTHLDSRNQRFERGPAHTEITQQVVCHRDRTDKPRSPEDLEEVVLKVTAASSYVERLEVLAERYDALTFQEDQRGSEQLLMAVEEGRLACTVADSNIVRLNRRYLPHLDVTMDLTEGQNLGWYLAEGQERLAQQAFEWMNSRAGDEVIAAMENRYYTYVGEFDFVDLRALKRRMESRLPRYQRHFEQAEAETDMPADLLAALAYQESHWDPQARSPTGVRGMMMLTGRTAESLGVNDRLDPEQSIMGGARYLADRHERLPEHIPEPDRTFLALASYNVGRGHLLDARQLARDLGRDPDDWQEMREVLPLLSDERYYPNLRYGYARGYEPVHFVARIRNYRDVIRQAFE
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F 2, Murein lyase F 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: GATB_MYCAP
Sequence: MNNFEAIIGIEIHLELNTKTKMFSPSKIDFNAEANTTVNQIDLGYPGTLPLLNKEAVVSGIKLAKALNMTIDRELHFDRKNYFYPDLPKGYQITQFYRPIGSNGYVEINTDLGTKKISIERIHLEEDTARQYHGEKTKLDYNRAGVPLIEIVSNPVISSADEAVAYVDMIRRIALSLNISSAKMEQGSLRADINISLRPKGYSKFGTKVEIKNINSFRAIKNAIEYEIKLQEQKILTNEPILQQTKRYDEETQSTIVMRTKTGTIDYKYFPESNIPFIKLSDEFINNVKLNELPWEKESRYKKEEIQDIYIKSLTNDIELANYFDSINYADRNKLSKLFFAEVVSLANSKNVKAYELNIKTTDLEKTIDLLDKEIISGKSFKKIVPLLVNFDGDIDQLIKEHDLVQISDENIITKWVNEIIAKNEALVTEYTERSEKVIKFVLGNIMKVWGGKVNPQKANEVLLKILNEKFK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: GLMU_BURCH
Sequence: MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARTLQPSRLVVVVGHGAEQVKAAVAAPDVQFAVQAEQLGTGHAVRQALPLLDPAQPTLVLYGDVPLTRASTLQRLVDAARDGRYGILTVTLDDPTGYGRIVRDASGFVTRIVEQKDASPEELKIAEINTGIIVTPTAQLSMWLGALKNENAQGEYYLTDVVELAIEAGFEVVTSQPDDEWETLGVNSKAQLAELERIHQRNVADALLVDGVTLADPARVDVRGTLRCGRDVSIDVNCVFEGNVTIADNVTIGANCVIRNASVGAGTRIDAFTHIDGAELGANTVIGPYARLRPGAQLADEAHVGNFVEVKNAVIGHGSKANHLTYIGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVGSDTQLVAPVRVGRGVTIAAGTTIWKDVAEGVLALNEKTQTAKSGYVRPVKKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_SHEB2
Sequence: MNVVQGNIEAKNAKVAIVISRFNSFLVESLLEGALDTLKRFGQVSDDNITVVRVPGAVELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQVALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGGEAALSLLEMVNVLQELEQQLL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: KTHY_CHLTB
Sequence: MFIVVEGGEGAGKTQFIQALSKRLIEEGREIVTTREPGGCSLGDSVRGLLLDPEQKISPYAELLLFLAARAQHIQEKIIPALKSGKTVISDRFHDSTIVYQGIAGGLGESFVTNLCYHVVGDKPFLPDIIFLLDIPAREGLLRKARQKHLDKFEQKPQIFHQSVREGFLALAEKAPDRYKVLDALLPTEASVDQALLQIRALI
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NAGB_ALKCK
Sequence: MNIIHVKNYEEMSQKAAALLFERIQQSPKITLGLATGGTPENTYTALIAKAKENGQSFSHVQTFNLDEYVGLPAEDKNSYRHYMEQRLFDHIDIPKEKTHLPNGMAPSLEEECRAYENMIADAGGIDIQLLGIGSNGHIGFNEPGTPFSSKTHVVELAEETRKANARYFPTLEDVPKQAITMGIQTIMEAKEILLLISGKAKAEAFAKLCSDEVTEAFPASILNKHPNVTVIADEEAASVYTQKAHL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RPOA_PSESM
Sequence: MQISVNEFLTPRHIDVQVVSPTRAKITLEPLERGFGHTLGNALRRILLSSMPGCAVVEAEIDGVLHEYSAIEGVQEDVIEILLNLKGLAIKLHGRDEVTLTLSKKGSGVVTAADIQLDHDVEIVNPDHVIANLASNGVLNMKLTVARGRGYEPADSRQSDEDESRSIGRLQLDSSFSPVRRIAYVVENARVEQRTNLDKLVIDLETNGTLDPEEAIRRAATILQQQLAAFVDLKGDSEPVVIEQEDEIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLDNWPPASLKKDDKATA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: LSM3_BOVIN
Sequence: MADDVDQQQTTNTVEEPLDLIRLSLDERIYVKMRNDRELRGRLHAYDQHLNMILGDVEETVTTIEIDEETYEEIYKSTKRNIPMLFVRGDGVVLVAPPLRVG
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).  The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm3.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.