PharMolix/UniProtQA huggingface dataset:
Protein: RECF_CHLMU
Sequence: MRVHSLFLKDFRNYSELRLELGPEMNSIFGLNAQGKTNILEALYILSLGRSFRTSRLTEAIRFGSSHFFIEAVFSQNQVFHTLSIQVDKRGKKILFDGAPITKLSALVGLFPVILFSVKDTTIIEGSPAERRRFLDLLLAQASEKYTGQIALYHKALDQRNAAIKTQDYKTIAAWNSPLIAYGSLVALLRYECAKKLHKIFQNLWDNTLKETLSLRYESSLITTESPTLNDIASNYYEQLRLANTKDFELGYTTVGPHRDELIITLNDLPVSKFSSEGQKHSLLAVLRFAECVYLQEEFLIHPLLCMDDIHACLDQNRLDQLFQLSTSLGQTVTTSTICPNHLDSNSSIFHVTQAQVSLVTSNFL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPF_BPMU
Sequence: MPQQTIDLAYAARLPPKEAVAYFRAKGYNITWNWYEQLADAHARAFTVAKATRMDVLTTIREEVERAVSEGITREEFTRTLAPRLQKLGWWGKQIIVDAEGNAKEIELGSPRRLATIYNVNTRTAYGAGRYAQMMNTADLYPYWQYVAVMDGRTRPEHARLHNMVFQYDDIFWQTHYPPNGWNCRCRVRALSAARMKELGLQVSYGASFMNTREVDAGTDESTGEIFRTSSTTFDNGRVKMTPDVGWSYNPGSAAFGTDQALIRKLVEVRDAQLREQVVQTLNNSRERQLAFSLWLKRLAGSRQTGHEIRALGFMTGSVAEAVYQRTGNMPARLLVMNGKSLATTADAALKPEDLQRLPSLMAKPQAVLWDRENHQLLYVVATRDGTARIVVRTSQTVGRQNDRADVLVSISRVSAQSLEAAIADGMIDVLEGHVEVNK
What is the function of this protein?
Involved in capsid assembly.
What are the official names of this protein?
Putative capsid assembly protein F, Gene product 30, gp30, Gene product F, gpF.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Associated with the capsid, might be a minor capsid protein.
Protein: CD209_PONPY
Sequence: MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGVLVLQLLSFTLLAGLFVQVSKVPSSISQEQSRQDSIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVSELPEKSKQQEIYQELTQLKAAVSELPEKSKLQEIYQELTQLKAAVSELPEKSKLQEIYQELTRLKAAVGELPEKCKLQEIYQELTRLKAAVDELPEKSKLQEIYQELTQLKAAVGELPEKSRLQEIYQELTQLKAAVERLCHPCPWEWTFFQGNCYFISNSQRNWHDSITACQEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICKKSAASCSRDEEQFLSPAPATPNPPPA
What is the function of this protein?
On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates.  May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2.  Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells (By similarity).
What are the official names of this protein?
CD209 antigen, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN1.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL21_CHLPM
Sequence: MQALIKISDKQYLVQKGDTLFVPRQKTDIGGTMEIASMARIDGANTVLNPAETVTAKVLGHVKDDKVVVFKKKRRKRYQSRNGHRQQMTQIEVVSL
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RUVB_FUSNN
Sequence: MERIISELEMPNEIEIQKSLRPKSFDEYIGQENLKEKMSISIKAAQKRNMVVDHILLYGPPGLGKTTLAGVIANEMKANLKITSGPILEKAGDLAAILTSLEENDILFIDEIHRLNSTVEEILYPAMEDGELDIIIGKGPSAKSIRIELPPFTLIGATTRAGLLSAPLRDRFGVSHKMEYYNENEIKSIIIRGAKILGVKINEDGAIEISKRSRGTPRIANRLLKRVRDYCEIKGNGTIDKLSAKNALDMLGVDSNGLDDLDRNIINSIIENYDGGPVGIETLSLLLGEDRRTLEEVYEPYLVKIGFLKRTNRGRVVTSKAYQHFKKVEVKI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RL32_RHIE6
Sequence: MAVPKRKTSPSKRGMRRSADALKAPTYVEDKNSGELRRPHHIDLKTGMYRGRQVLTPKESA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: GLDSA_STRLV
Sequence: MAQSLAVQGGSAVRTRPWPVWPRPAAGAAEAVQQVLSSGRWSISGPYRGAASQERRFARAFAEYNGVAHCVPAASGTASLMLALEACGVGAGDEVIVPGLSWVASGSTVLGVNAVPVFCDVDPRTLCLDPEAVEAAVTERTKAIVVVHLYSAVADMDALTALAERHSLPLIEDCAQAHGAAYRGVKVGALATAGTFSMQHSKMLTSGEGGAVITRDADFARRVEHLRADGRVLAGQRPGPGEMELVETGELMGNNRCLSEFQAALLTEQLKDLDAQHAIRRRNAALLDGLLRESGYVPQETSEGTSTRTHYTYAVRLPEGRLTHVGLATVARALSAELGCTVAPSYAPITRNRLYDPASRRRFALGVEHQALTDPKRFELPVAEDAARRVLTLHHAALLGAEDDMRDIAAAFGKVLRHGADLTA
What is the function of this protein?
Catalyzes the PLP-dependent transamination of 2-deoxy-scyllo-inosose (2-DOI) to form 2-deoxy-scyllo-inosamine (2-DOIA) using L-glutamine as the amino donor.  Also catalyzes the transamination of 3-amino-2,3-dideoxy-scyllo-inosose (keto-2-DOIA) into 2-deoxystreptamine (2-DOS).
What are the official names of this protein?
L-glutamine:2-deoxy-scyllo-inosose aminotransferase, L-glutamine:DOI aminotransferase, L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase, L-glutamine:amino-DOI aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. L-glutamine:2-deoxy-scyllo-inosose/scyllo-inosose aminotransferase subfamily.
Protein: ENGB_EDWI9
Sequence: MARQTYNYHVTHFVTSAPDIRHLPEDTGIEVAFAGRSNAGKSSALNTLTNQKSLARTSKTPGRTQLINLFEVEDGIRLVDLPGYGYAEVPEEMKRKWQQALGEYLQKRQCLKGLVVLMDIRHPLKDLDQQMIAWAVEVGLPVLLLLTKADKLASGARKAQLNMVREAVLPFMGDIQVDAFSSLKKFGVDKLRDKLDTWFSEITPQQADKDDDPSIGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: EDN2_BOVIN
Sequence: MPTALCSIALALLVALHEGKSQAATTPIPEQPAPLPRARGSHLRTRRCSCSSWLDKECVYFCHLDIIWVNTPGQTAPYGLGNPPRRRRRSLPRRCECYSARDPACATFCHQRPWTDAVAVPGSGSPAAAFQDGKTQATAGELLQRLRVISATKIHFARQQQKPTRETRPTHSRQRKR
What is the function of this protein?
Endothelins are endothelium-derived vasoconstrictor peptides.
What are the official names of this protein?
Endothelin-2, ET-2, Preproendothelin-2, PPET2.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BUD23_MOUSE
Sequence: MASRSRRPEHSGPPELFYDQNEARKYVRNSRMIDIQTKMTERALELLCLPEGQPSYLLDIGCGSGLSGDYISEEGHYWVGIDISPAMLDAALDRDTEGDLLLGDMGQGVPFRPGSFDGCISISAVQWLCNANKKSDVPARRLYCFFSSLYSALVRGARAVLQLYPENSEQLELITTQATRAGFTGGVVVDFPNSAKAKKFYLCLFSGPSTSLPKGLTESQDADQASESMFTSERAPHKKARRDLVKKSREWVLEKKERRRRQGKEVRPDTQYTGRKRKPRF
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA.  Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity.  Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity.  Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity.  Locus-specific steroid receptor coactivator.  Potentiates transactivation by glucocorticoid (NR3C1), mineralocorticoid (NR3C2), androgen (AR) and progesterone (PGR) receptors.  Required for the maintenance of open chromatin at the TSC22D3/GILZ locus to facilitate NR3C1 loading on the response elements.  Required for maintenance of dimethylation on histone H3 'Lys-79' (H3K79me2), although direct histone methyltransferase activity is not observed in vitro.
What are the official names of this protein?
Probable 18S rRNA (guanine-N(7))-methyltransferase, Bud site selection protein 23 homolog, Williams-Beuren syndrome chromosomal region 22 protein homolog, rRNA methyltransferase and ribosome maturation factor.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Cytoplasm, perinuclear region. Cytoplasm. Note=Localized diffusely throughout the nucleus and the cytoplasm. Localizes to a polarized perinuclear structure, overlapping partially with the Golgi and lysosomes. Localization is not affected by glucocorticoid treatment.
Protein: DOHH_SCHPO
Sequence: MSSEPVPQAVIDELERVLVNLDKSNPLSFRYRALFSLNALAKKGDKRAVDAIYKAFIDDSELLKHEMAYVMGQSGQQYAVQPLINIVNDLDQQVMVRHEAAEALGALGFTESLPVLEKYYKEDPLAPIRETCELAIARIQWKNGLDKNNEKITPSMYDSVVDPAPPMPDHEQDVKSEVAKLRSEIVDQNLPLFYRYRVMFRLRNIGNEEAVLALTDGFKDPSPLFRHEIAFVFGQMIAPASVPALIKVLENTEEVPMVRHEAAEALGGIANDECLPVLKKFSKDDVRVVAESCIVALDMIEYEKSGDMEYAYIPKVSA
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SACDR_BOVIN
Sequence: MAVVIKFFRWIWQKISRWVFFWKHKAKSVIMDHTDSKKNELKAEKAFKVSETFKLVEPPKEAKVSKMDVSPKVVDPCLLAKTTMDGAAVEAGRRRRSLLKLPQAAVKSVSMLMASALQSGWQMCSWKSSVSSTSVASQMKTRSPLESREAAMLREVYLVLWAIRKQLRQVARRQERRRRHHLRAHMGPQPDPAQGLKQDARSPL
What is the function of this protein?
May play an important role in acrosome formation and nucleus shaping during spermiogenesis.
What are the official names of this protein?
Sperm acrosome developmental regulator.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Detected in acrosome of round spermatids and spermatozoa.
Protein: PFD3_CAEEL
Sequence: MSDTADSLSARGIPKSELIEDVESWLTKEKLSIEEAEVVLREKYGKYKYVESSMLAQKVRMSEKIPEFENSLSIIDTLIAKRAADESFETTFLLSDDVYTKATVQKPEKVSIWLGANVMVEYDLENARKLLDKNRGSVQKVVDELTNELSYIKDQITTTEVNMSHIVNFGVNKRRAALAVNNGAK
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
What are the official names of this protein?
Probable prefoldin subunit 3.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
Protein: YR069_MIMIV
Sequence: MLSSYCNPNEPIPREIPSLKAHIFEYMYQYRNWSKFVGDVKKNHGSIDDLEFTITEFKHVHYMNVARVIVHGVEKFNKCCDNINNNDINLDCELTKNIQKHFQGCSEKIPQIYIYGNFCRSIVSGQLYDNINIMFHDDKCSEMFRQFCIPKNYICRNLQWNWSKGNVRGIDYELNFKGYNDYKVHLFLSWCNDMNIVPDNIYFDVDSLYSTISHENIHFMSSLKSLYPDCNVDKIIKNCTNNKFILLDNTKSPTITHPQPFVFSRNIHLKCINVNKEQHIKFLFLKMKSKGWKCLNEDCETPWCILQKDLLH
What are the official names of this protein?
Uncharacterized protein R69.
What is the protein family that this protein belongs to?
Belongs to the mimivirus R69 family.
Protein: MTGA_LARHH
Sequence: MLKWIVRGVAALLALFLLYQLWIFGHIVYWKWNNPATTAFMDEQQARLAETNPDAELRYRWVDYGRISPQLKRAIVASEDAKFLQHEGFDWEGIQTAWEKNLQKGRIVAGGSTISQQLAKNLFLSSRRTPWRKAEEALITVMLEAVMDKRRIFEIYLNVIEWGDGVFGAESAARHYYRVPASRLSAGQAAKLAAMVPNPRYYDTHRNDRTLLRKTKIIQRRMNFVAIP
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRAD1_BOVIN
Sequence: MAEFLNDQDTRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKCDMETHMATEHCQVTCKCNKKLEKRQLKKHEETECPLRLALCQHCDLELSVLKLKDHEDYCGARTELCGTCGRNVLVKDLKTHPEVCGRDVEEKRVEAAMPPNAYDESWGPDRIWIASQLRQIEALDPPMRLPRRPLRAFESDLFQSRTTNQRSMTAQFPIQNNLLEEQERQERNRSRQTPKERGEDSANLDFMLALSLQNEGQAPTLAEQDFWRVIYEADQSREGPSALNDIRGAVDETMLPCEFCEELYPEELLIDHQTSCNPSCALPPLSVGSTSPRGVEDPDAIFQKLMRESAGGQFESLMGFSSSAPVEDSVVIPCEFCGVQLEEEVLFHHQDQCDQRPATANNHVSEGIPSQDLQPRETSPELPKRRVRHQGDLSSGYMNDLKQEMAKGPTYPLPSSRPPNNTTAPPNRLSTSTSGPRPGCQPSPPRALKLNNLDSQGVRGHSRNSHNGALAPGHVPAAYPARSLYPENLVPSFPRGPSGRYGASSRSEGGRNPRVTPTAASYRSRTAKAKTPKQQGAGDAEEEEE
What is the function of this protein?
Negative feedback regulator that controls excessive innate immune responses.  Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways.  May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation.  May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).
What are the official names of this protein?
TRAF-type zinc finger domain-containing protein 1.
Protein: CTO1_YEAST
Sequence: MKTIIISDFDETITRVDTICTIAKLPYLLNPRLKPEWGHFTKTYMDGYHKYKYNGTRSLPLLSSGVPTIISQSNFNKLFADELKYQNHNRVVELNSVNEITKQQIFKSISLDQMKTFARDQNHEDCLLRDGFKTFCSSVVKNFESDFYVLSINWSKEFIHEVIGDRRLKNSHIFCNDLKKVSDKCSQSYNGEFDCRLLTGSDKVKILGEILDKIDSGCNKEGNSCSYWYIGDSETDLLSILHPSTNGVLLINPQENPSKFIKITEKIIGIPKDKISSFEADNGPAWLQFCEKEGGKGAYLVKSWDSLKDLIMQVTKM
What is the function of this protein?
Protein required for cold tolerance (PubMed:25725023).  Plays a role in the regulation of phosphate uptake (PubMed:25725023).
What are the official names of this protein?
Cold tolerance protein 1.
What is the protein family that this protein belongs to?
Belongs to the CTO1 family.
Protein: ZBTB6_MOUSE
Sequence: MAAESDVLHFQFEQQGDVVLQKMNLLRQQNLFCDVSIYINDTEFQGHKVILAACSTFMRDQFLLTQSKHVRITILQSAEVGWKLLLSCYTGALEVKRKELLKYLTAASYLQMVHIVEKCTEALSKYLEIDLSMKNNQHTDLCQSSDTDVKNEEENSDKDCEIIEISEDSPVNLDFHVKEEESNALQSAAETLTSERMRMQSPELSAVDGGFKENEICILHVESISTDDVENGQFSQPCTSSKAGIYFPETQHSLINSTVENRVTEVPGNTNQGLFSENSDGSHGTVNEIQNLDENFSLRHQCPRCPRGFLHVENYLRHLKMHKLFLCLQCGKTFTQKKNLNRHIRGHMGIRPFQCTVCLKTFTAKSTLQDHLNIHSGDRPYKCHCCDMDFKHKSALKKHLTSVHGRSSGEKLSRPDLKRQNLL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 6, Zinc finger protein 482.
What are the subcellular locations of this protein?
Nucleus.
Protein: FTSK_XANCP
Sequence: MAKQVPERSKPAEGKSSSRKPAAADTPRRQKLWRDLALIAVAPLLLYLLASLFTYSAADPGWSQTGSVVAPVHNMGGRVGAWIADVLLQLFGYVAFLLPVVLGAVAWIALFGMDKEGQAEADLGPALRLVGMVGFLIASTGFLHLRLFNGDVAGAGGILGRLVSNSLSAGFGALGANLFVVVLLLVSITLATGLSWFVVMERIGKWVLALGPLLQRKSHQATEWQQTRVMREEREEVRKVDAVKQAKREPVKIEPPPAPVVEKSERAKRDTQIPMFQGVSTDGSDLPPLALLDDPKPQAKGYSEETLETLSRQIEFKLKDFRIEAQVVGAYPGPVITRFEIEPAPGVKVSQISSLDKDIARGLSVKSVRVVDVIPGKSVVGLEIPNVTREMIFLSELLRSKEYDKSASPLTLALGKDIAGRPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLFKASHKELRMLMIDPKMLELSVYQGIPHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSAVGVRNLAGFNKKVKDAEDAGQPMMDPLFKPNPELGEAPRPLETLPFIVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRVAFQVSSKIDSRTILDQSGAEALLGNGDMLYLPPGTALPDRVHGAFVSDEEVHRVVEHLKASGPVAYVDGVLDEVQTMGDGTVVGATGLPESSGGGGDESDPLYDEALRIVTETRRASISGVQRRLKIGYNRAARLIEAMEAAGVVSPPEHNGDRTVLAPPPPK
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: RLR12_PLAVT
Sequence: MRGAYYVITALLVVASSEISADSGHQLQVYDHDVVAAENAAAKTLPQRFLRGSRNVPDDLAHEERAITSELVEEGAKLIPRAAEDVEEISRVAEAVGKRPHVAEEDVLNKASGANEAFKKPRNTATDDAFQGITTKQLLPLSYKQWDTEIKSMRIPKPEKYQENIQSVHDAFVDVCDEDLKPTISETARLWNLFDRSFKPLTTRLHQHALTQYAKEYVLRDELRIETESARSNEKTMSTSASMLNLVLNWYFQRWVRMYNIFGKHRSELIDTPSKVARSRGGTTGTSRGTALHKHLNVPLNAASTSKDKSSVLTFKSQRTFDGNPKQSKVQNSELVKPVFTKSAISDDHPVFSKNLKLSSEGPSAAFAPYRSGDNSVSTKNSKVGVGGTNSAFVPYKPPSVPIF
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 12.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: FTSH_HAHCH
Sequence: MSNTDPQPPQKLPLNWVVWTLAVALMLYYLPAMRDRPEPAIKLPYSEFRMLLREGQISSVTLRGSELDGKFITPRMFPEQRRQYSRFLTQLPDFGNEAILAELEEQNIPLEVKEGHDASSSKVILLSYLPWIMFMIILFWLSRRTFRNFSGRGGAFDFDKRLETQFECQKPDTTFDEVAGQTNAKREVQELVEYLRDPDRFHRVGALAPRGVLLMGPPGTGKTLLARALAGEAGVNFYPMSASEFIEVFVGVGASRVRQLFKIAKENSPSIIFIDELDSVGRTRGAGYGGGHDEREQTLNQILAEMDGFAGHDAVIVLAATNRPDVLDPALMRPGRFDRHVTLDLPDQEGRVAILKVHARHIPLADDVNLNQVAAGTPGFSGADLKNLINEAAIQAARENRDHVHSLDFDIARDKIIMGAERTLIIPPDEKHRLAVHESGHTLVAYYLPNTDPLYKVSIVPHGRSLGGTHQLPLQERHTYPEEYLRDKLAVMLAGRIAERELLGSVSTGADDDIHQATGLARAMVSRWGMSKEVGPVDLRDSEEHPFLGREMAQPHHHSEFSAEIIDKAVRELLVAAETTAADLISTHREKLDRLVALLERSETLHKAQIDECLQTGAS
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: GQ1_HHV6Z
Sequence: MRPPRRSAPILVCAISMATALSNATVHRDAGTVESTPPPDDEDNYTAKYYDDSIYFNIYDGTNPTPRRRTLPEIISKFSTSEMSRLGGLKAFVPVDYTPTTTLEDIEDLLNYAICDDNSCGCLIETEARXMFGDIIICVPLSAESRGVRNLKSRIMPMGLSQILSSGLGLHFSLLYGAFGSNYNSLAYMERLKPLTAMTAIAFCPMTSKLELRQNYRLEKARXNLIVNIELLKIQNHGGQTIKTLTSFAIVRKDSDGQDWETCTRFASVSIEDILRSKPAANGTCCPPRDVHHDRPTLQSSNSWTRTEYFEPWQDVVDAYVPINDNHCPNDSYVVFQTLQGHEWCSRLNKNDTKNYLSSVLAFKNALYETEELMETIGMRLASQILSLVGQRGTSIRNIDPAIVSALWHSLPEKLTTTNIKYDIASPTHMSPALXTIFIQTGTSKQRFRNAGLLMVNNIFTVQARYSKQNMFEKKIYGYEHLGQALCEGGHVFYNPRDVYFQNIKMAATEPTVVRT
What is the function of this protein?
Plays a role in virus entry by participating in host receptor binding at the cell surface.
What are the official names of this protein?
Glycoprotein Q1, gQ1, Glycoprotein 105, gp105, Glycoprotein Q-80k, gQ-80k, HCLF1 protein.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen.
Protein: MCA9_ARATH
Sequence: MDQQGMVKKRLAVLVGCNYPNTRNELHGCINDVLAMKETILSRFGFKQDDIEVLTDEPESKVKPTGANIKAALRRMVDKAQAGSGDILFFHYSGHGTRIPSVKSAHPFKQDEAIVPCDFNLITDVDFRELVNQLPKGTSFTMISDSCHSGGLIDKEKEQIGPSSVSSNISPAIETTNKTITSRALPFKAVLDHLSSLTGITTSDIGTHLLELFGRDAGLKFRLPAMDLMDLLETMTAREKHVDSGILMSGCQADETSADVGVGNGKAYGAFSNAIQRVLNENEGAMKNKQLVMMARDVLERLGFHQHPCLYCSDQNADATFLSQP
What is the function of this protein?
Cysteine protease that cleaves specifically after arginine or lysine residues.  Does not cleave caspase-specific substrates.  Required for proteolytic processing of GRI (PubMed:25398910).
What are the official names of this protein?
Metacaspase-9, AtMC9.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: TBB_ENCIN
Sequence: MREIIHLQTGQCGNQVGCKFWETISGEHGIDQSGRYVGTSDNQLERVNVYYNEASSKKYVPRAVLIDLEPGTMDAVRQGPFGELFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVMDVVRKEAESSDCLQGFQITHSLGGGTGAGMGTLLLSKIREDFPDRMICTFSVVPSPKVSDTVVEPYNATLSIHQLVENADETFCIDNEALYDMCFRTLKLNNPGYGDLNHLVSLVMSGVTTCLRFPGQLNAYLRKLAVNMIPFPRLHFFVVGFAPLTAVGTQKFKTYSVSELTQQMFDSKNMMTACDPKKGRYLTVAAMFRGKISMKDVDEQMSMVQSKNSSLFVEWIPSNVKTAVCDIAPTGLEMSATFVGNTTSIQELFKRISDQFTVMFRRKAFLHWYTGEGMDEMEFSEAESNMNDLLSEYQQYQDATVEDAEEFLVN
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YPT7_MAGO7
Sequence: MSSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSASYKATIGADFLTREVLVDDRQVTMQLWDTAGQERFQSLGVAFYRGADCCVLVFDVNNSKSFDALDSWRDEFLIQASPRDPDNFPFVVLGNKIDVEESKRVISTKRAMTFCQSKGGIPYFETSAKEAINVEQAFEVIARNALAQEESEEFSGDFQDPINIHIDNDRDGCAC
What is the function of this protein?
Ypt/Rab-type GTPases are key regulators of membrane trafficking and intracellular vesicular transport.  They act as molecular switches that convert between GTP-bound and GDP-bound states, and regulate virtually all steps of membrane traffic from the formation of the transport vesicle at the donor membrane to its fusion at the target membrane.  In the GDP-bound state, Ypt proteins are predominantly cytosolic, solubilized through the interaction with a GDP dissociation inhibitor (GDI).  In the GTP-bound state, the proteins are membrane bound and interact with specific effector proteins that select cargo, promote vesicle movement, or verify the correct site of fusion (By similarity).  Required for fungal morphogenesis, vacuole fusion, autophagy, stress resistance and pathogenicity (PubMed:25991510).
What are the official names of this protein?
Ypt/Rab-type GTPase ypt7.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Vacuole.
Protein: PTC1_AGAAN
Sequence: MAFLKKSLFLVLFLAIVPLSICEEEKREEENEEKQEDDDQSEKRGLVSGLLNTAGGLLGDLLGSLGSLSGGES
What is the function of this protein?
Peptide with no antimicrobial activity.  May act in synergy with cationic peptides by enhancing their activity.  Has a moderate hemolytic activity.
What are the official names of this protein?
Plasticin-A1, PTC-A1, Dermaseptin AA-2-5.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Plasticin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.