PharMolix/UniProtQA huggingface dataset:
Protein: LTHAD_PSESP
Sequence: MQLSSYHDVIKAAERLEGFANRTPVFTSRTLDAETGAQVFIKCENLQRTGSFKFRGAFNALSRFDEAQRKAGVVAFSSGNHAQGIALAARLLQMPATIVMPTDAPAAKVAATREYGATVVFYDRITEDREQIGRTLAEQHGMTLIPSYDHPDVLAGQGTAAKELLEFTGPLDALFVGLGGGGMLSGTALATRALSPDCLLYGVEPEAGNDGQRSFQTGSIVHIDTPATIADGAQTQHLGNHTFPIIRENVNDILTVSDAELVESMRFFMQRMKMVVEPTGCLGLAALRNLKQQFRGQRVGIIVTGGNVDIEKYASLLKG
What is the function of this protein?
Catalyzes the deamination of L-threo-3-hydroxyaspartate to oxaloacetate and ammonia.  Shows a high specificity towards L-threo-3-hydroxyaspartate as other 3-hydroxyaminoacids, i. e.  D,L-erythro- and D-threo-3-hydroxyaspartate, D-threonine, L-threonine, D,L-allothreonine, D,L-threo-3-phenylserine, D-serine, and L-serine, are not substrates for this enzyme (PubMed:10481099, PubMed:19193709).  Exhibits no detectable serine and aspartate racemase activity (PubMed:19193709).  Might play a role in the detoxification of naturally occurring 3-hydroxyaspartate in Pseudomonas sp.  T62 cells (PubMed:19193709).
What are the official names of this protein?
L-threo-3-hydroxyaspartate ammonia-lyase, L-threo-3-hydroxyaspartate dehydratase, L-THA DH.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: DEF2_SORBI
Sequence: RVCMGKSAGFKGLCMRDQNCAQVCLQEGWGGGNCDGVMRQCKCIRQCW
What are the official names of this protein?
Defensin-like protein 2, Small protein inhibitor of insect alpha-amylases 2, SI alpha-2.
What is the protein family that this protein belongs to?
Belongs to the DEFL family. Protease inhibitor I18 (RTI/MTI-2) subfamily.
Protein: COAD_AERHH
Sequence: MTNKVIYPGTFDPVTNGHTDLIGRAAKLFDEVVVGVANSPSKRPLFDLDERVQLARQVTAHLPNVKVVGFSGLLVDFAREQQANVLIRGLRAVSDFEYEFQLANMNRRLMPELESVFLTPAEENSFISSTLVKEVALHGGDIRQFVDPAVAAAIKAKQTK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPRB_MYCSJ
Sequence: MTLPPQPSRLKPPRNTSSLSLRWRVMLLAMSMVAMVVVLMSVAVYAVVSRALYDDIDNQLHSRARLLIESGSLAADPGKAIEGTAYSDVNAMLVNPGRSIYTANQQGQTLPLGEAEKDVISGELLLSLRTANHQRILAVHLTNGSSLLISKSLAPTGQVLGRLGTVLLIVGGVGVAVAAIAGGMVARAGLRPVGRLTQAAERVARTDDLRPIPVFGSDELARLTEAFNMMLRALTESRERQARLVSDAGHELRTPLTSLRTNVELLMASQAPGAPRLPEEEMAGLRADVIAQIEELSTLVGDLVDLTRDEAGGVVYETVDMAEVVDRSLERVRRRRNDIEFDVNVVGWQVYGDAAGLARAVLNLLDNAAKWSPPGGRVGVRLTQTDPVHAELVVSDQGPGIPEAERRLVFERFYRSTAARAMPGSGLGLAIVKQVVLKHGGALRVEDTVPGGNPPGTSFYVMLPGRPLTPGGNGTAPVPAAQFDPDMRSAGSRADRRVIKNTETNGKSRSASKEL
What is the function of this protein?
Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host.  In response to environmental signals MprB acts as both a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to MprA, and a protein phosphatase that dephosphorylates phospho-MprA (By similarity).
What are the official names of this protein?
Signal transduction histidine-protein kinase/phosphatase MprB, Mycobacterial persistence regulator B.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUD_DELAS
Sequence: MQQFTVHKGLVAPMDRENVDTDAIIPKQFLKSIKKTGFGVNLFDEWRYLDHGEPGQDPASRKPNPDFVLNQPRYAGASILVARKNFGCGSSREHAPWALDQYGFRAILAPSFADIFFNNCFKNGLLPIVLPEATIDMLFNEIAAFPGYELTIDLDRQVIVRPQGEEIPFDVIAFRKFCLLNGFDDIGLTLRHADKIRAYEAERLATKPWLAHTLVQR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: NSA2_PICGU
Sequence: MPQNEYIEKHIKQHGRRLDHEERKRKRAAREGHRVAKDAQTLKGWRGKQFAKQRYSEKVAMKKKIKAHQESKVKGPSTPKENDGEALPTYLLDRKDTNTAKAISSSIKQKRMEKADKFSVPLPKVKGISEEEMFKVIKTGKSKTKSWKRMITKHTFVGEGFTRRPVKMERIIRPSALRQKKANVTHPELGVTVFLPILGVKKNPQSPMYTQLGVLTKGTIIEVNVSELGLVTAGGKVVWGKYAQITNEPDRDGCVNAVLLV
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May play a part in the quality control of pre-60S particles (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein NSA2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CLPX_PELPB
Sequence: MTREREPGKSRTKSGSGTTDQVFCSFCGRSAQEVNSMIAGPKAFICDRCIKTSFDILRKEVNAVPPVAKVPEQPFQPRLVSPKAIMDSLGQYVVGQDAAKKSLAVAVYNHYKRIDSQEQQQADDEVVIEKSNILLIGPTGTGKTLLAQTLANLLEVPFSIVDATSLTEAGYVGDDVETILARLLHAADFNLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGAVVGVPPKGGRKHPEQQLININTKNILFICGGAFEGLDKLIAKRVSKSSMGFGAKVKTTQIGYDPEILKLVMQDDLHEYGLIPEFIGRLPVISTLEMLDEKALRNILVEPKNAITKQYKKLFEMDGVELEFTEEALDKVVKIAIERGTGARALRSVLENVMIDIMFEIPSMKNTHKCVITADTIENKAAPEYFSGDRKKKKIA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: VE4_BPV1
Sequence: MANDKEIAQTESGSHPKDLKETLQEKKPSQPSLSLLCSAPPPAVPSEQASVGYGTVLARTPTIFLQARGALFSALPPPRAGHGTGGLGIKAGRRGAVARLHRGRTSDSPKAHHQ
What is the function of this protein?
Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions.  Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes.  Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin.  Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity.  Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine (SR) proteins that have critical roles in mRNA metabolism.  Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.
What are the official names of this protein?
Protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: GABR1_MOUSE
Sequence: MLLLLLVPLFLRPLGAGGAQTPNVTSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKTYDPSINCTVEEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRSQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDILTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSKKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQIRSRRHPPTPPDPSGGLPRGPSEPPDRLSCDGSRVHLLYK
What is the function of this protein?
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2 (PubMed:10773016, PubMed:10075644).  Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins (By similarity).  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase (PubMed:10773016, PubMed:10075644).  Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis (PubMed:10075644).  Calcium is required for high affinity binding to GABA (By similarity).  Plays a critical role in the fine-tuning of inhibitory synaptic transmission (By similarity).  Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials (PubMed:10075644).  Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi- pass membrane protein. Cell projection, dendrite. Note=Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane. Colocalizes with ATF4 in hippocampal neuron dendritic membranes (By similarity).
Protein: PRNK_METJA
Sequence: MVDNMISKAYYTTEIPEDRFEALSCIKDSQKPLKIILLGGVDSGKTTLATFLANELLNLGFKVAIVDSDVGQKSILPPATISLAFPETNFNNLYEIKPYKSYFVGSTAPIQFFGEMITGTKLLCDYAEDKADIIIVDTTGLISGSGADLKRMKIEMIKPDIIIALEKRNELKSILKPFENKIRVFYLKVYENAKSFSREERKEIRAEKWKEYFKNSKIYNIGFNDVVIGGTKVFQGEKILEDEKYLLESLFKWKILYGSKCDGRYTIVKRDLVNMPRQIDKNILYYIEPERFNNLIVGLIDEDSFCIGLGILKTIDFENETLEILTPISEEDIKNIREIRFGRIRVDENGEELGLLDRDSI
What is the function of this protein?
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA).  Exhibits a strong preference for ssRNA (By similarity).
What are the official names of this protein?
Polyribonucleotide 5'-hydroxyl-kinase MJ1315, Polynucleotide kinase MJ1315.
Protein: RIMP_NITEC
Sequence: MSLFELLEPTIAGMGYELVDIEQSAPGRLLRVFVDKKDGAITLADCVAVSNHLGQLLAVENIDYNRLEVSSPGLDRPLKKRADFVRFVGESIRIRLRIALQGQRNFVGTLTEVGDDALMLNVDGKLLQFELKNLEKARLIPKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_CLOPS
Sequence: MNFDNLEREDEQIAHLVQKEKERQENSIELIASENFVSKAVMEAMGSYLTNKYAEGYPSKRYYGGCHVVDEVEDLARERVKKLFGAEHANVQPHSGSQANMAVYFSILESGDTVLGMDLSHGGHLTHGSPVNFSGRLFNFVSYGVDKETETINYETVRELALKHKPKLIVAGASAYSRIIDFKTLREIADEVGAYLMVDIAHIAGLVATGLHPSPVPYADFVTSTTHKTLRGPRGGLILCKEKFAKVLDKNIFPGIQGGPLMHIIAAKAVCFKEALEPSFKTYMEQVVKNAHVLAEALESYGFKLVSNGTDNHLILVDLTNKDITGKDAEILLDSIGITLNKNTVPNETRSPFVTSGVRIGTPAITTRGFKEEEMKEIASIINDAIKEKDGDLEPLKARVKALCAKYPLY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B3A4_RAT
Sequence: MKLPGQEDFEGSDAHENVCSEQLDGDLGPGSGLDGPSDIDNGKAQGCKDPLLFIQLNELLGWPQALEWRETGRWLLFEEKLDIGAGRWSAPHVPTLALPSLQKLRGLLAEGIVLLDCPARSLLELVEQVVRVESLSPELRGQLQALLLQRPQHHIQTTGIRPCRRSNAFRKASRDEDTLLKHQNPLRQKLPPGAEAAAVLAGELGFLEQPLAAFVRLQNPVVLEPLTEVVLPSRFFCLLLGPSTLGRSYHETGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLQEVTALPPGRWDRTARIPPPKCLPSQHKRFPSKLQEVTSLSRQSAALAENKHHHGPHTPIPELQRTGRLFGGLVQDVRRKACWYPSDFLDALHPQCFSAVLYIYLATVTNAITFGGLLGDATEGAQGVLESFLGTAVAGATFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLALVATEASLLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLIRAYPIQRPGSPAYSCFCQYPGTGGNASEFDSTMFKDTEDVLNVHPGLVNASFLPPSECIRQGGYPRGPSCHTVPDIAFFSLLLFFTSFLCAIALKHVKNSRLFPSVVRKVFSDFSSVLAILLGCGLDAFLGLATPKLLVPTEFKPTLPGRGWLVSPFGANPWWLSVAAALPALLLSILIFMDQQITAVILNRAEYRLQKGAGFHLDLFCVAVLMLFTSALGLPWYVSATVISLAHMDSLRRESKACVPGEDPNFLGIREQRLTGLVVFILTGVSIFLAPVLKFIPMPVLYGIFLYMGVAALSSMQFMKRVQLLLMPRKHQPDVLLLRHVPLIRVHLFTAIQLACLGLLWVIKSTPAAIVFPLMLLGLVAVRKALEWIFSPQELLWLDELMPEEEKTIPENRPEPEHLFSGNDSENSELMYQPKAPEINISVN
What is the function of this protein?
Probable apical anion exchanger of the alpha-intercalated cells of kidney.  May participate in HCO3(-) absorption.
What are the official names of this protein?
Anion exchange protein 4, AE 4, Anion exchanger 4, Solute carrier family 4 member 9.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Note=In contrast to the rabbit ortholog, it is present on basolateral membrane of cortical collecting duct kidney cells.
Protein: TSAD_FRATM
Sequence: MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASREHIAKLNLLAKKIFKETGLSFEDIDCIAYTAMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSPLLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESIDDAAGEAFDKTTKLLGMGYPGGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLCYAFQDAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNRGYQIFFPPMKYCTDNGAMIALAGAYRYVNGFKDSNLEINVKARSPL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSD3_AMAPH
Sequence: MSDINATRLPSFFFPIPCISDDIEMVLTRGER
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:24613547).
What are the official names of this protein?
MSDIN-like toxin proprotein 3.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: RSMH_SHEB5
Sequence: MSQEFAHLSVLLAETVGGLNIKDDGIYIDGTFGRGGHSRQVLQQLGENGRLIAIDRDPQAIEAAKQFADDPRFQIVHGGFGQLADYVEELGLVGKIDGVLLDLGVSSPQLDDAERGFSFMRDGPLDMRMDNSQGQTAAQWLARAEIEDMAWVFKTYGEEKNARHIARCIAADRDKTPFLRTKDLADLIARITKSKERNKHPATRVFQAIRIYINSELDQIDQALEGAVNVLAPQGRLSVISFHSLEDRIVKRFIRRHSQGESVPHGFPVTEDQINKSRKLRAVGKAIMPSDEEIERNARARSSVLRIAERLDY
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALDHY_YEASX
Sequence: MSKSKTKTDKRNQSSLSRIKLSALHYCMSDAEPSIAYLQDNSAFINNEWHNLVLEKIFPVYNPSTEEDITQVSEKSQHDSTEEDITQVSEKSQHDDDKAVVDISERGRLLNILADLIERDRDILAAIEHLDNGKPFDEAYLLDLASVLKELRYTAGWADKLHGTLRFAITIPTFQDLRFLRYTRHEPVGVCGEIIPWNIPLLMYIWKIGPALAAGNTVVLKPEELTPLTALTVATLIKEAGFPPGVVNVVSGYGPTAGAACLSHKDNDKLAFTGSTLVGKVVMKAAAKSNLKKVTLELGGKSPMIVFIDADLDWAVENAHFGVFFNQGQCCIAQSRITVHESIYDEIVERDLEKAKKQVLGNPFESDTRYGPQILKIEFDSIPRLINSAKAEGAKVLCGGGRDDSCVGYYIQPTVFADVTDEMRIAKEEIFGPVITISRFKSVDEAIKRVDNTKYGLAAYVFTKDKAIRISAALKAGTVWVNCVHVASYQIPFGGNKNSGMGRELGEYGLE
What are the official names of this protein?
Aldehyde dehydrogenase 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CYB6_SPIMX
Sequence: MGKIYDWFEERLEIQAIADDIISKYVPPHVNIFYCLGGITLTCFLIQVATGFAMTFYYRPTVAEAFASVQYIMTDVNFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVILAVLTVSFGVTGYSLPWDQIGYWAVKIVTGVPDAIPIIGAPIVELLRGSVSVGQTTLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRMD_ACIBY
Sequence: MFFAVITLFPEMFDAITAYGISGRAAKRDIVQVTCINPRDFAEGNYRRVDERPFGGGPGMVMMAEPLAKAINHAKQLASRAGCVHVPVVYMSPQGKTLNEQAVQQFVDYDGLIVLCGRYEGVDERLIQHYVDQEWSIGDYVLSGGELPAMVLLDSIIRRLPNVMSDEQSAIQDSFVDGLLDCPQYTKPDQFEGLDVPEILKSGHHANIEKWRFLQRYQRTLERRPELIEQVTLTKQQKKWLSDEQG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1264_MYCTO
Sequence: MTDHVREADDANIDDLLGDLGGTARAERAKLVEWLLEQGITPDEIRATNPPLLLATRHLVGDDGTYVSAREISENYGVDLELLQRVQRAVGLARVDDPDAVVHMRADGEAAARAQRFVELGLNPDQVVLVVRVLAEGLSHAAEAMRYTALEAIMRPGATELDIAKGSQALVSQIVPLLGPMIQDMLFMQLRHMMETEAVNAGERAAGKPLPGARQVTVAFADLVGFTQLGEVVSAEELGHLAGRLAGLARDLTAPPVWFIKTIGDAVMLVCPDPAPLLDTVLKLVEVVDTDNNFPRLRAGVASGMAVSRAGDWFGSPVNVASRVTGVARPGAVLVADSVREALGDAPEADGFQWSFAGPRRLRGIRGDVRLFRVRRGATRTGSGGAAQDDDLAGSSP
What is the function of this protein?
Catalyzes the formation of the second messenger cAMP.
What are the official names of this protein?
pH-sensitive adenylate cyclase MT1302, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Protein: THIM_METAC
Sequence: MNEPLKTIRETKPLIHHITNWVTIYECANMTRAFGALPVMAHAPEECADMTKISSALVLNIGTLTSEIIDSMLLSAAAANERDIPVVLDAVGVGATKFRDEMAAKILASVHIDIIKGNYSEIAKLAGENAETKGVEATSIDADPAKVAKAFAKAESCVVVMTGKEDIISDGDRTFIVKNGHELMGSIVGTGCMAASIVGLFAAVNRDYCDAAKDALCYFGASGELAAAKSSGPGSFKVHLYDEVFNLSDEKVKSMKNFEEK
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: CFA97_HUMAN
Sequence: MDQFGDILEGEVDHSFFDSDFEEGKKCETNSVFDKQNDDPKERIDKDTKNVNSNTGMQTTENYLTEKGNERNVKFPPEHPVENDVTQTVSSFSLPASSRSKKLCDVTTGLKIHVSIPNRIPKIVKEGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSSSSSSSLSSSSSGSGTDCLDAGSDSHLSDSSPSSKSSKKHVSGITLLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQKVKIKKQENVSQEIYEDVEDLKNNSKYLKAAKKGKEKHEPDVSSKSSSVLDSSLDHRHKQKVLHDTMDLNHLLKAFLQLDKKGPQKHHFDQPSVAPGKNYSFTREEVRQIDRENQRLLKELSRQAEKPGSKSTIPRSADHPPKLYHSALNRQKEQQRIERENLALLKRLEAVKPTVGMKRSEQLMDYHRNMGYLNSSPLSRRARSTLGQYSPLRASRTSSATSGLSCRSERSAVDPSSGHPRRRPKPPNVRTAWL
What are the official names of this protein?
Cilia- and flagella-associated protein 97.
What is the protein family that this protein belongs to?
Belongs to the CFAP97 family.
Protein: GUC2B_PIG
Sequence: MASRAAAGLLLCGVALVFLVLLQGTQSVYIQYQGFRVQLKSVKKLSDLEGQWAPSPRLQAQSPQPSVCHHSALPPDLQPICQSEEAASIFQALRTIAGDDCELCVNVACTGCS
What is the function of this protein?
Endogenous activator of intestinal guanylate cyclase.  It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.  May be a potent physiological regulator of intestinal fluid and electrolyte transport.  May be an autocrine/paracrine regulator of intestinal salt and water transport (By similarity).
What are the official names of this protein?
Guanylate cyclase activator 2B.
What is the protein family that this protein belongs to?
Belongs to the guanylin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NTPJ_ENTHA
Sequence: MTIMKKRVRKRLSPVQLIAAGFFILILFGGSLLTLPFFSRSGESTHFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMTLIEIGGLGFMMIPILFFAIAKKKISFSMRIVLKEALNLEEMSGVIKLMIYILKFAVVIQVIGAVALSVVFIPEFGWAKGIWFSIFHAVSSFCNAGFDLLGDSLLADQTNVYLIMVVSALIIAGGLGFIVWRDILSYHRVKKITLHSKVALSVTALLLIGGFILFLITERNGLTLVKGTFTERLANTFFMSVTPRTAGYYSIDYLQMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGILLIQMHAMFKGKTRAEAFGRTIRQAAVLRALTLFFVTLSLCVVAIMVLSVTETIPKTSGIEYIAFEVFSAFGTVGLTMGLTPDLTLIGKLVIISLMYIGRVGIMTVVFSLLVKANRAEANYKYPEESIMLG
What is the function of this protein?
Mediates electrogenic transport of potassium as well as sodium.  Acts probably as a potassium-sodium cotransporter.  Major sodium reentry pathway at high pH values.
What are the official names of this protein?
Potassium/sodium uptake protein NtpJ, K(+):Na(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the TrkH potassium transport family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMD_FRATH
Sequence: MGRSRYHNKLKEGIFEAEITALSHDGRGIAKVDGKTTFIPFTLPGEVVKFEYTFTKAKFDEAKVVEYVKKSLNRVNPPCDHFQICGGCSLQHMSTDAQIEHKQQTLINQLKYIGNGVEPENILPPLRTSNTEGYRNKARLGVRYVSKKGKILVGFRERNGRFLADIDKCIVLNPLVGDKITEISSFIETLSIYQHIAQLEIAIDDTRPAMIVRHLEPFTNEDLEKLRSFAQENNYWIYLQSKGPDTIFRLYPQGDVEPKKLSYQPAAGIDIGFEPNDFTQVNNDINKKMIKRAIELLDISENDSIIDLFCGLGNFTLPISQHAKTVIGVEGEPTMVKRAKETADNNNITNVNFYAANLFESFEDKEWFNNFEYNKMLLDPPRAGAQEVCNNIEKFNVKRIVYVSCDTAALARDAGILVNTKGYKLISAGVMDMFPHTMHVESIAVFEKI
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.