PharMolix/UniProtQA huggingface dataset:
Protein: TREF_SALA4
Sequence: MLNQKLNPTPSEDLTIDVDLLYETDPCELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSTKLFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRRFVENHFWLPETLSSEYVSNPENSLKEHIDQLWPILTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLALNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDAGRLASIRTTQFIPIDLNAFLYKLESAIANISALKGERDTEALFRQKASDRRAAVNHYLWDDENGCYRDYDWRREEMALFSAASIVPLYVGMANHEQADRLANVVRSRLLTPGGIMATEYETGEQWDKPNGWAPLQWMAIQGFKLYGDDMLGDEIAHNWLKTVNHFYQEHHKLIEKYHISGGTPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_BORBR
Sequence: MSSVSAAGATPPASPGCIAGIGMDLLRIERIERALARHGDRFAQKILGPEELAKFHARRRRDPARGVRFLATRFAAKEAFSKAIGLGMRMPMSWRRVQTLNAPGGRPVLVIGAELADWFDARFGAAHVSITDESDMAAAYVIVERKPAPDGRP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_PSEPG
Sequence: MSTLLQHAQIDWDDQGRPHSRQYDDVYFAVNEGIEETKHVFLGQTRLAERFANLAPHTCGVIGETGFGTGMNFFCAWQLFDQHAHRDARLHFVSVEKYPLGHADMARAVSLWPELAAYTEPLLEQYVAVHPGFQQFTFANGRVTLTLLIGDVLEQLPQLDAQIDVWFLDGFAPAKNPDMWTPELFAQLARLSHPGTVLGTFTTTGWVRRSLVEAGFAMKKVPGIGKKWEVMSGAYVGPVPGPKAPWYARPAVAQGPREALVIGAGLAGSTTAASLARRGWQVTVLERHEAPAQEASGNPQGVLYLKLSAHGTALSQMILSGFGYTRRQLQRLQRGQDWDACGVLQLAFDAKEAERQGKLAAAFDHDLLHALERAEAEAIAGVALPAGGLFYPEGGWVHPPALCQQQLQHPGIRLLTHQDVIELRNIGQHWQAWAGDRLLASAPVVVLAGAADVRRFEPCAQLPLKRIRGQITRLPATASSRALRTVVCAEGYVAPPRGDEHTLGASFDFHSEDLAPTVAEHQGNLALLDEISVDLAQRLGVAELDAEQLQGRAAFRCTSPDYLPIVGPLADSQAFAEAYAVLGRDARQVPDVACPWLGGLYVNSGHGSRGLITAPLSGELVAAWVCGEPLPLPRAVAEACHPNRFALRRLIRGK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG2_METRJ
Sequence: MTDVTPANAARIGIGGPVGSGKTALIERLIPVLQARGVDLAVITNDLVTKEDAERLRRSGLIDPSRVEAVEAGACPHTVIREDPTLNIAAGDALEARFPGLQLLVFESGGDNLASTFSLDLVDWWIFVIDVAGGDDIPRKRGPGVLRCDLLVINKIDLAPHVGVDLEGMLAEAARVRGGKPVIATNARAGLGIDRVADAIGRAVLFTP
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG 2.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_STRMU
Sequence: MKITKIEKKKRLYLIEIDEAEHFYITEDTIVHFMLSKNKEILPEQLEEIKTFAQFSYGKNLALYYLSFKQRTEKEVKDYLIRHDINTTVISQILTQLKEEKWLDDSKYIDNILQQNLHSGDKGAFVLKQKLLQKGIESQLIEDMLKDFDFSSICIKTAQKLLKKYQSKLPKRALKDKLKQALTTKGFSYQEAQIALEDLDIENNSENEEELIYKELDKQYRKYSKKYENYELRQRLTQSLARKGFAFDAIKNALREYL
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_HELP2
Sequence: MSEMVDLKEFLAELGKTQKELKNVIEQAKDIGLELKTNSKMTPEQAGKLYKYIVDGIKEQIQANQPAKNPEQDNKDDLNTAVASKSLNKKVFKTPKKEETKSQPKPKKTKEKKKEAPTPIAKKKGGIEIVNTFEDQTPPVENAPKVVSHSQIEKAKQKLQEIQKSREALNKLTQSNANNANSTNNANNAKKEISEVKKQEQEIKRHENIKRRTGFRVIKRNDETENETENSVTESKKPTQSAAAIFEDIKKEWQEKDKQEAKKVKKPSKPKATPTAKNNKSHKIDFSDARDFKGNDIYDDETDEILLFDLHEQDNLNKEEEEKEIRQNINDRVRVQRKNPWMNESGIKRQSKKKRAFRNDNSQKVIQSAIAIPEEVRVYEFAQKANLNLADVIKTLFNLGLMVTKNDFLDKDSIEILAEEFHLEISVQNTLEEFEVEEVLEGVKKERPPVVTIMGHVDHGKTSLLDKIRDKRVAHTEAGGITQHIGAYMVEKNNKWVSFIDTPGHEAFSQMRNRGAQVTDIAVIVIAADDGVKQQTIEALEHAKAANVPVIFAMNKMDKPNVNPDKLKAECAELGYNPVDWGGEHEFIPVSAKTGDGIDNLLETILIQADIMELKAIEEGSARAVVLEGSVEKGRGAVATVIVQSGTLSVGDSFFAETAFGKVRTMTDDQGKSIQNLKPSMVALITGLSEVPPAGSVLIGVENDSIARLQAQKRATYLHQKALSKSTKVSFDELSEMVANKELKNIPVVIKADTQGSLEAIKNSLLELNNEEVAIQVIHSGVGGITENDLSLVSNSEHAVILGFNIRPTGNVKNKAKEYNVSIKTYTVIYALIEEMRSLLLGLMSPIIEEEHTGQAEVRETFNIPKVGTIAGCVVSDGVIARGIKARLIRDGVVIHTGEILSLKRFKDDVKEVSKGYECGIMLDNYNEIKVGDVFETYKEIHKKRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_CALBD
Sequence: MIDSIVGIIQEVFSNYVILNYNNLYIKIFCNSTKFSEFLGKEKRVYVSLKFNENLSELECYGFLTREERELFLKLQKVTGVGSKLALQILSSIDFQELIVEIAKGNVAKLEKVKGIGKKTASRIILELKETLKKEFKVASTSGKEEKTYEKLEEISLALLSLGYDIDEVNQVLSSEDFSELSLEDGIKLALKKLSKI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: GSPJ_PSEAE
Sequence: MRLQRGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQRMRELVRAMGALERDLTQAVERPVRDELGDNRGAFLSEGENDQIVEFTRGGWRNPLGQARSRLQRVRWSLSGETLERRYWLVLDRAQDSKPRVQQVLDGVTALSWRFLDKEHNWQGHWPTDEGSEEERLESLPLAVEMTLEHRHYGKLVRVWRLLDPPLKQDQPQGQPGGENGENGEGGVPQPPEGMPGAPE
What is the function of this protein?
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm (PubMed:9282737).  Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates (PubMed:19828448, PubMed:30346996).  Type II pseudopilus confers increased bacterial adhesive capabilities (PubMed:12700254).
What are the official names of this protein?
Type II secretion system protein J, T2SS protein J, General secretion pathway protein J, PilD-dependent protein PddD.
What is the protein family that this protein belongs to?
Belongs to the GSP J family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SYFB_NITOC
Sequence: MKFSEAWLRTWVDPDISRETLVERLTLAGLEVESTEPVAAPFKGVKAARIVAVEPHPSAPRLQVCQVDIGSGSLLTVVCGAPNARAGLWAPLAIIGAQLPAGIRIELAKLQGVESFGMLCSAAELGLAEQSAGLLELPEGDFPGVDLHEFLQFDDISIEVDLTPNRSDCLSVAGIAREVGVLTQSPVTEPAIEPVTAQIGDIFPVTVTAPAACPRYLGRVLRGVNPQTQTPWWLRERLRRSGIRSLGLVVDVTNYVMLELGQPMHAFDLERLKGGIQVRYGQADEALTLLDGTHLRLDEETLIIADQQRALALAGIMGGEESGINNQTRHLFLESAFFNPSVIAGRARFYGLHTDSSHRFERGVDPELPRRAMERATALLLEIAGGQAGPVIEVADSSQLPPQATIILRKARIHRVLGVEIAESRITEQLTRLGLKVERIEEGWEVKVPSFRFDLALEVDLIEELGRLYGYDRLPSTRPVGQIQPVLKTEAGAFIDRIRQVLVDRDYQEAITYSFVDQELQQLLDPEGSPLVLNNPISTDMAVMRTTLWTGLVQALQYNSYRQQERIRFFEYGLTFNGQLADLKQERTIAGLISGASYPEQWGLVGRPADFFDLKGDVEAILSLVGEQRNCFEFMAASHPALHPGQSAQILREGQAVGWLGALHPWLESKLDLSSRAYLFSLQLEAVERGSLPVFQSLSKFPAIRRDIAFLVNANIPVQVVFDCLKGCESDILKEFQLFDVYTGKGIDPDKKSLALKLILQHPSYTLTDDRVNIFIERVMALLVTELGAIIRE
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHME_PHANO
Sequence: MSRVRYNNSVALPATQTVIKQNEDGLLTIQKDFPLPEIRSDRLLVRVEYVAINPCDWKMSERFPAPGAVDGCDFAGTVVALGSDVSKTGRFQVGEKVCGGVHGSNPIDPTTGSFAEYLSADAEFTFKVPGYMGLKEAAAVGGTGIGTMGLALSKSLGLPGSPTRPVGETDSKYVLVPIAVCSPKNYDLVKSYGAVKAFDYHSPTCAQDIRAYTKNRLAHIIDPIVEAKTMQLCYAAMGRAGGKYCALEAYADELCTRKVVKPELVMGMAILGRKVALNHGYGSEADAGKRAFGIEWYREMQDLLDAGRLMTHPVRVVPGRFDGIMKGLQMLKTKQVSGEKLIVQLGSNN
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of the mycotoxins phomacins, leucine-derived cytochalasans with potent actin polymerization-inhibitory activities and monocot-specific antigerminative activities (PubMed:31815421).  The first step in the pathway is catalyzed by the hybrid PKS-NRPS phmA, assisted by the enoyl reductase phmE, that are responsible for fusion of the leucine precursor and the polyketide backbone to produce a 2-pyrrolidone intermediate (PubMed:31815421).  The polyketide synthase module (PKS) of phmA is responsible for the synthesis of the polyketide backbone and the downstream nonribosomal peptide synthetase (NRPS) amidates the carboxyl end of the polyketide with the leucine precursor (PubMed:31815421).  Because phmA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase phmE (PubMed:31815421).  Reduction by the hydrolyase phmG, followed by dehydration and intra-molecular Diels-Alder cyclization by the Diels-Alderase phmD then yield the required isoindolone-fused macrocycle (Probable).  A number of oxidative steps catalyzed by the tailoring cytochrome P450 monooxygenase phmB, the FAD-linked oxidoreductase phmC and the short-chain dehydrogenase/reductase phmF, are further required to afford the final products, phomacin D and phomacin E (PubMed:31815421).
What are the official names of this protein?
Trans-enoyl reductase phmE, Phomacin biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: KS6A2_MOUSE
Sequence: MELSMKKFTVRRFFSVYLRKKSRSKSSSLSRLEEEGIVKEIDISNHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSKEATDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLVQEPSQQDVPKAPIHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWIVNREYLSQNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSSLAQRRGMKRLTSTRL
What is the function of this protein?
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation.  May function as tumor suppressor in epithelial ovarian cancer cells (By similarity).
What are the official names of this protein?
Ribosomal protein S6 kinase alpha-2, S6K-alpha-2, 90 kDa ribosomal protein S6 kinase 2, p90-RSK 2, p90RSK2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, Protein-tyrosine kinase Mpk-9, Ribosomal S6 kinase 3, RSK-3, pp90RSK3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GLMM_RUMCH
Sequence: MGRLFGTDGVRGVANLELTPKLAYQLGQAGAYVLTGETKHTPKILVGMDTRISGDMLEAALISGICSVGAQVVSLGVIPTPAIAYLTRQYDADAGVVISASHNPFEYNGIKFFNSNGYKLPDAIEDKIEEIIQNGGEDLPKPVGQNIGFKCYQENALEDYVNFVKGTITGDFEGIKVAIDCANGASFQAAPMALFDLKADVSVINNEPDGTNINSGCGSTHMRQLQAYVKEIKADIGFAFDGDADRVLAVDENGNIVDGDQIMAIIGLYLKDKGILSQNTIVATVMSNMGLDIMAKNKGLTIEKTKVGDRYVLEEMLNKGYMLGGEQSGHIIFLDHNTTGDGLLTAVQLLKVLKDSGKKLSELAGVMEILPQVLINAKVTNEKKYKYLDDEVIKKMCKELEDEFKGEGRVLIRPSGTEPLVRVMIEGKDKDIITRRAKELVRVIEGRLS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: PYRG_RHOP5
Sequence: MARYIFITGGVVSSLGKGLASAALGALLQARGYKVRLRKLDPYLNLDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRPATRADNITTGRIYQDILTKERRGDYLGATIQVVPHVTNAIKEFIVDSNDAYDFVLVEIGGTVGDIEGLPFFEAIRQIKNDLPRGDVIYIHLTLLPYIPSAGELKTKPTQHSVKELRSIGIQPDILLCRTDRSIPKEERRKLGLFCNVRESAVIEARDADSIYAVPEAYHAAGLDEEVLAAFGIASKGEPGLDRWTVINERIRNPEGEVTIAIVGKYTGMKDAYKSLIEALSHGGIANKVKVNIDWIESEVFENEDPAPFLEHVNGILVPGGFGQRGAEGKIEAARFARERNVPYFGICFGMQMAVIEAARNLAGIADANSTEFGPTKEPLVGLMTEWLRGNQLEKRSNAGDLGGTMRLGAYPAALKRGSRVSQIYGDVLEISERHRHRYEVNTAYKDRLEQHGLRFSGLSPDGVLPEIVEYEGHPWFIGVQFHPELKSRPFEPHPLFASFIEAAMAQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: FRDA_HELPY
Sequence: MKITYCDALIIGGGLAGLRASIACKQKGLNTIVLSLVPVRRSHSAAAQGGMQASLANAKKSEGDNEDLHFLDTVKGSDWGCDQQVARMFVTTAPKAIRELASWGVPWTRIKKGDRPAVVNGEHVTITERDDRHGYILSRDFGGTKKWRTCFTADATGHTMLYAVANEALHHKVDIQDRKDMLAFIHHDNKCYGAVVRDLITGEISAYVSKGTLLATGGYGRVYKHTTNAVICDGAGAASALETGVAKLGNMEAVQFHPTALVPSGILMTEGCRGDGGVLRDKFGRRFMPAYEPEKKELASRDVVSRRILEHIQKGYGAKSPYGDHVWLDIAILGRNHVEKNLRDVRDIAMTFAGIDPADSKEQTKDNMQGVPANEPEYGQAMAKQKGWIPIKPMQHYSMGGVRTNPKGETHLKGLFCAGEAACWDLHGFNRLGGNSVSEAVVAGMIIGDYFASHCLEAQIEINTQKVEAFIKESQDYMHFLLHNEGKEDVYEIRERMKEVMDEKVGVFREGKRLEEALKELQELYARSKNICVKNKVLHNNPELEDAYRTKKMLKLALCITQGALLRTESRGAHTRIDYPKRDDEKWLNRTLASWPSAEQDMPTIEYEELDVMKMEISPDFRGYGKKGNFIPHPKKEERDAEILKTILELEKLGKDRIEVQHALMPFELQEKYKARNMRLEDEEVRARGEHLYSFNVHELLDQHNANLKGEHHE
What is the function of this protein?
The fumarate reductase enzyme complex is required for fumarate respiration.
What are the official names of this protein?
Fumarate reductase flavoprotein subunit, Quinol-fumarate reductase flavoprotein subunit, QFR flavoprotein subunit.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MSRB_STAS1
Sequence: MIKKNKNDLNEMEYLVTQENGTEPPFQNEYWNHFEKGIYVDKISGKPLFTSEEKFESDCGWPSFSKALADEEIVELVDKTFGMVRTEVRSEDANSHLGHVFNDGPKESGGLRYCINSAAVQFIPYEKLEELGYGDLIPHFEK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: HTPX_THESM
Sequence: MGLGMWLRTGVLMAFLTGLLMAIGYVLGNETGMMFAFMFALVMNFFSYWYSDKIVLTWYRARILEEDEAPELYEIVRGLAQEAGIPTPKIAIVPTETPNAFATGRNPKNAVVAVTQGLLRILNRDELEGVIAHELSHIKNRDVLIQTLAAVMAGAIMMVARWAGWMLWLGGFGGRDRDRDASGALGAILLIVLAPIAAMLIQMAISRAREYLADETGAKISGKPWALARALEKIEHAVSMRPIKNGNPATAHMFIINPFRGVSFAELFSTHPPTQKRIERLRKIAENMGIAF
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DOCK1_MOUSE
Sequence: MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEVASKQVEERLQEEKSQKQNMDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPMESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDSNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQAVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETLKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKGELEEKGHSATGKGMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTNLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRTYVASAEKPGVNEQLYKAIKALEYIFKFIVRSRVLFNQLYENKGEADFVESLLQLFRSINDMMSSLSELTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPAGLLTVQKLSCLIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEELEACCQLLSNILEVLYRKDVGPTQRHVQIIMETLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNTMQNKVFLRAINQYADMLNKRFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATLPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKDNRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCAAHLTQRDGFQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYETEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPSFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKTSPGQYIQCFTVKPKLDLPPRFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKISSMVQQHLDDPGLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHGQIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGVRTMPSGLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSFSSDSTPSRPGSDGFALEPLLPKKMHSRSQDKLDKDDPDKEKKDKKKEKRNSKHQEIFDKEFKPADSSLQQSEAVILSETISPLRPQRPKSQVINVIGNERRFSVSPASPSSQQTPPPVTPRAKLSFSIQPSLELNGMMGMDVADVPPPLPLKGNMADYGNLMENQDMMVSPTSPPPPPPQRQQPPPLPSKTPPPPPPKTTRKQTSVDSGIVQ
What is the function of this protein?
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility.  Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen.  Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP.  Its GEF activity may be enhanced by ELMO1.
What are the official names of this protein?
Dedicator of cytokinesis protein 1, 180 kDa protein downstream of CRK, DOCK180.
What is the protein family that this protein belongs to?
Belongs to the DOCK family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-trisphosphate.
Protein: YAEH_ECOLU
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: PIR_ECOLX
Sequence: MRLKVMMDVNKKTKIRHRNELNHTLAQLPLPAKRVMYMALAPIDSKEPLERGRVFKIRAEDLAALAKITPSLAYRQLKEGGKLLGASKISLRGDDIIALAKELNLPFTAKNSPEELDLNIIEWIAYSPDEGYLSLKFTRTIEPYISSLIGKKNKFTTQLLTASLRLSSQYSSSLYQLIRKHYSNFKKKNYFIISVDELKEELIAYTFDKDGNIEYKYPDFPIFKRDVLNKAIAEIKKKTEISFVGFTVHEKEGRKISKLKFEFVVDEDEFSGDKDDEAFFMNLSEADAAFLKVFDETVPPKKAKG
What is the function of this protein?
Initiation for plasmid R6K DNA replication.
What are the official names of this protein?
PI protein, Replication initiation protein.
What is the protein family that this protein belongs to?
Belongs to the initiator RepB protein family.
Protein: RS20_MYCAP
Sequence: MANIKSKVKSIAKQEEFRQRNNAMKTRVRKAIRAAREAVLAKEEGFEKKVFEAHSIIATAVQKGVYHPNKGARKSSRLDHFVNEQKSKQ
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: HSCA_ALISL
Sequence: MAFLQISEPGQSAAPHQHKLAVGIDLGTTNSLVASVRSGEANTLPDMKGNVILPSVVQYQDDKICVGANAYQSAASDPQNTIISVKRLMGRSLKDIQTRYPDLPYQFTESDNGLPVIHTTQGDVNPIQVSAEILKSLSNRAEVTLGGSLEGVVITVPAYFDDAQRAGTKDAATLAGLNVLRLLNEPTAAAIAYGLDSGQEGIIAVYDLGGGTFDISILRLSKGVFEVLATGGDSALGGDDFDHVLSQWIKDQAEITTALSNQEQRELLTLATETKVALSDADSVTVSFKEWSGTITADIFNQLIQSLVKKTLMACRRALKDADISSEDVMEVVMVGGSTRTPIVRRSVGDYFAKTPLTSIDPDQVVAIGAAIQADILVGNKPDTEMLLLDVIPLSLGIETMGGLVEKIIPRNTTIPVAKAQEFTTFKDGQTGMMVHVVQGEREMVEDGRSLARFSLKGIPPMTAGAAHIRVTYQVDADGLLSVTAMEKSTGVQSHIQVKPSYGLSDNEVATMLKDSMTYAKDDMKARALAEQQVEADRVIEGLVVALNNDGDALLSKEEQTVILQAVEALITVRKGTDTQAIEDGIKHADEASQEFAARRMDASIRAALAGQSIDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RTC5_CLAL4
Sequence: MGQNASATKTQATYKQTLPKSRIKELFQTRALQTLSARELASIASKLNIASFNDSHVVTLTDLAYLLQLSNDKEKNVSSIHEDFACVVRILYDSLTILGNLPFLGDSLEADDNSQLTLKSLIVASAVHTGRINSFWNDAEYLKLLFISLSFPPTKQSSEKAAEKWEQVNEDSAELSFRTVPDEKDSSAQIALKIKWADFEHLTTYDDLDVECLRVPADNMVKLITLLLLVRSVRLQSHDKMQFLLQERIEKCWNKFEGAALSLVRFMNVDVNASNMNSKCITYEQFNSGVVNGFLNLFTDVFRRLFENGFLGSIVADPKAPQPLNENIEATATEKESKAAADKKQERIKKAYNFEETRLVNDASLALIATALQASGINEEISRETVVELYNGAHAGFSIRSLESKIFKWQAPTIFLISGKRLRSKTIAQNKRYQQFEDMFPRFFRSTENPRKAWQTDSDKITYAVYVEEPWRNSNKSNFGNELTTIVNLSPRYDIYTSKHDPVIKGMSVYFNNLGMGIGFGNDQPINKNNVRRIIPGKVSLTVEANLEFAVFRHIFNSSANTSAFFNFSRQEAARNEDYEDRFMITDLEVWGIGSTKELEEQKKQWEWEEKQAQARQSVNVGTLSEDRALLEMAGLIGNHGSGGSV
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLPA_METMA
Sequence: MPEIRQLSEGIFEVTKDKKQLSTLNLDPGKVVYGEKLISVEGDEYRTWDPRRSKLGAMVLKKFDIPLKRNSKVLYLGAASGTTVSHVSDIVSEGAVYSVEFAPRSMRDFIGLASRRKNIFPILADAGKPDSYAHIVEPVDVIFQDVAQPNQAEIAARNAVRFLKKDGYLLLSIKARSIDTAASPKEIFKEEVKKLEQAFEPGFEVLTARELMPYHEDHLGVMARLKK
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.