PharMolix/UniProtQA huggingface dataset:
Protein: IXTPA_HELHP
Sequence: MVIVLASANQHKICEFQAMLKNVKEKVKVYAYGELLETFEIAENGNSFKENATLKVKAIYQALYTLSQSTMQENIRNLFAQPLAIIAEDSGLCVPVLNGEPGIYSARYAHHKQFASMQYKNTDEANLYCLLNALTHCAPTPAFFVAHIALIFIKPYFCTYTLPPLEQCVIEHFEGILNGEVINEMRGNEGFGYDPLFIPAEHNPQSLTLAEFDMSAKNTISHRKKALSQCINRLFDKS
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: JMJD8_RAT
Sequence: MAAAGRFGLLLLIVLWTMVTVVLPASGEGGWKQSRLGTEAAVMEEERCTVERRAHLTYSEFMQHYAFLKPVILQGLTDNSKFRALCSRENLLASFGDNVVRLSTANTYSYQKVDLPFQEYVEQLLHPQDPESLGNDTLYFFGDNNFTEWAPLFQHYRPPPFRLLGTTPAYSFGIAGAGSGVPFHWHGPGFSEVIYGRKRWFLYPPEKTPEFHPNKTTLAWLLEIYPSLAPSARPLECTIQAGEALYFPDRWWHATLNLDTSVFISTFLG
What is the function of this protein?
Functions as a positive regulator of TNF-induced NF-kappaB signaling.  Regulates angiogenesis and cellular metabolism through interaction with PKM.
What are the official names of this protein?
JmjC domain-containing protein 8, Jumonji domain-containing protein 8.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Cytoplasm.
Protein: RL7A_METAC
Sequence: MAQLAKFDVPEELTNKALEALELARDTGKIKKGTNEATKAIERGNAKLVLIAEDIEPAEIVAHIGPLSEEKKAPYIFIKNQKELGAASGLGVSCATVAIVDAGKAAEMVQDIAQKLEALK
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGRC2_HUMAN
Sequence: MAAGDGDVKLGTLGSGSESSNDGGSESPGDAGAAAEGGGWAAAALALLTGGGEMLLNVALVALVLLGAYRLWVRWGRRGLGAGAGAGEESPATSLPRMKKRDFSLEQLRQYDGSRNPRILLAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASRGLATFCLDKDALRDEYDDLSDLNAVQMESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDEEDTKDHNKQD
What is the function of this protein?
Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity).  May serve as a universal non-classical progesterone receptor in the uterus (Probable).  Intracellular heme chaperone required for delivery of labile, or signaling heme, to the nucleus (By similarity).  Plays a role in adipocyte function and systemic glucose homeostasis (PubMed:28111073).  In brown fat, which has a high demand for heme, delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1 (By similarity).
What are the official names of this protein?
Membrane-associated progesterone receptor component 2, Progesterone membrane-binding protein, Steroid receptor protein DG6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family. MAPR subfamily.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Nucleus envelope. Endoplasmic reticulum.
Protein: MOC2A_CAEEL
Sequence: MISIKVLFFGEACQLVGKREEAIDFPEETDYEEIRKTILENYPALQKIEKVMMLAVDQEYANPGDRFELVRFTEIAVIPPLSGG
What is the function of this protein?
Acts as a sulfur carrier required for molybdopterin biosynthesis.  Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group.  In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, Molybdenum cofactor synthesis protein 2 small subunit, Molybdenum cofactor synthesis protein 2A, MOCS2A, Sulfur carrier protein MOCS2A.
What is the protein family that this protein belongs to?
Belongs to the MoaD family. MOCS2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_CLOBB
Sequence: MYAVLATGGKQYRVQEGDVIYVEKLDAEVDSTVELTEVLAVANDEGIKVGAPVVEGAKVTAKVLAQGKQKKVIVFKYKAKKDYRRKNGHRQPYTKLVIEKIEA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: YHC6_YEAST
Sequence: MKSSEPAPATPTGFRNSIWFIIFYLFVIQALGSAIISGGIEFAIAYAMYHSRVDLITLWAFPHTISGDCALSLFIQVGLTWASEEILVGFDDYKRPVFRLNKWITKPSPLKTESNEEIPPPKKRFIVDYFESKDNVVAKQNTLYHKHNWLFGYLEVNRGIIPKGKEATLKGFLTSQFIHDSTQSKFMNFIEWFVQKFIRSMILAIAMFIVIWPVTMGILAGIGHKVGSHDYYFNDYPLPQVMKLIYAVVIAFVCTPVAIIVIVLRNQFHEELYYEGLANGTLQQDQEVCSTGNRSSGSTDQDISTTKQQSQEAVA
What are the official names of this protein?
Uncharacterized protein YHL026C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UN13C_MOUSE
Sequence: MVASLFKSLILAYIHKLCKGMFTKKLGNTTKKKENRQQKKDQDFPTAGHTKPPKLSNALKSTVKKIAKCSSTRNFSIEDEEGHKDFSLSPTFSYRVAIANGLQTAVTNSDEDLLQELSSIESSYSESFNELRSSTENQVQSTHTMPVRRNRKSSSSLAPSEGSSDGERTLHTLKLGALRKLRKWKKSQECVSSDSELSTVKKTWGIRSKSLDRTARNPKTNVLEPGFSSSGCISQTHDVMEMIFKELQGISQIETELSELRGHVNALKYSIDEISSSVEVVQSEIEQLRTGFVQARRETRDIHDYIKHLGHMGSKVSLRFLNVPEERHEYVESVVYQILIDKMGFSDVPNAIKIEFAQRIGQQRDCPNAKPRPILVYFETPQQRDSVLKKSYKLKGTGIGISTDILTYDIRERKEKGVLPSSQTYESMDMKLSTPEPKAKKNAWLSPNDSDRELESDLSRSSYADSPAKGSSSKSSSKSHSARSKNKAANSRTSQKSDYNKRPSQPPASSTPEKQTPHYVEATPPLWHSQSDFFTLKLSRSESDFSKLCQSYSEDFSESQFFCRTNGSSLLSSSDRELWQRKQEGMPALYHRLQDQGLDETIPAVPGQAEIENTETVDSGMSNSMVCASGDRSNYSGSQLSLHEDLSPWKEWNQAGQGTDDVGLDSSTQEPFDYDTNSLSDQQLDLSSKDLDDLGKCHSDLQDDSESYDLTQDDNSSPCPGLDNEPQGQWVGQYDSYQEANSNDLYPNQSHPSMMYRSQSELQSDDSEGAQPKSWHSRLSIDLSDKTFKFPKFGSTLQRAKSALEVVWNKSTQSLSGCEDSGSSLMGRFRTLSQSTANESSTTLDSDIYTEPYYYKAEEEEDYCEPVADSETDYVEVMEQVLAKLENRTSITEVNEHIKDYDHPSYETPYETPQDEGYDGQADDIISEGELETLNEPAVEMELAEDENQNLPAESLEVMKPKRIRPSFKEAALRAYKKQMAELEEKILAGDSSSMDEKARIVSGNDLDASKFSALQVFGGAGRGLYGIDSMPDLRRKKTLPIVRDVAMTLAARKSGLSLAMVIRTSLNNEELKMHVFRKTLQALIYPISSTTPHNFEVWTATTPTYCYECEGLLWGIARQGMKCLECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDKTQTIITAMKERMKIRERNRPEVFEVIQEMFQISKEDFVQYTKAAKQSVLDGTSKWSAKITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFFFECHNSTDRIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLKINVEIKGEEKVAPYHIQYTCLHENLFHYLTEVKSNGSVKIPEVKGDEAWKVFFDDASQEIVDEFAMRYGVESIYQAMTHFSCLSSKYMCPGVPAVMSALLANINAFYAHTTVSTNVQVSASDRFAATNFGREKFIKLLDQLHNSLRIDLSKYRENFPASNSERLQDLKSTVDLLTSITFFRMKVLELQSPPKASAVVKDCVRACLDSTYKYIFDNCHELYSQLIDPSKKQDVPREDQGPTTKNLDFWPQLITLMVTIIDEDKTAYTPVLNQFPQELNMGKISAEIMWSLFALDMKYALEEHEKQRLCKSTDYMNLHFKVKWFYNEYVRELPAFKDAVPEYSLWFEPFVMQWLDENEDVSMEFLHGALGRDKKDGFQQTSDHALFSCSVVDVFAQLNQSFEIIKKLECPNPEALSHLMRRFAKTINKVLVQYAAIVSNDFSSYCDKETVPCILMNNIQQLRVQLEKMFESMGGKELDPEASTILKELQIKLNGVLDALSITYGESFQLTIEECIKQMGAELNQMRANGNSTANKNSAAMDAEIVLRPLMDFLDKTLSLSAKICEKTVLKRVLKELWKLVLNKIEKQIVLPPLTDQTGPQMIFIAAKDLGQLSKLKEHMIREDAKGLTPRQCAIVEVVLATIKQYFHAGGNGLKKNFLEKSPDLHSLRYALSLYTQTTDALIKKFIETQGSQSRSSKDAVGQISVHVDVTTTPGTGDHKVTVKVIAINDLNWQTTAMFRPFVEVCMLGPSLGDKKRKQGTKTKSNTWSPKYNETFQFILGNENRPGAYELHLSVKDYCFAREDRIIGMTVIQLQNIAEKGSYGAWYPLLKNLSMDETGLTILRILSQRTSDDVAKEFVRLKSETRSIEESA
What is the function of this protein?
May play a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway.  May be involved in the regulation of synaptic transmission at parallel fiber - Purkinje cell synapses.
What are the official names of this protein?
Protein unc-13 homolog C, Munc13-3.
What is the protein family that this protein belongs to?
Belongs to the unc-13 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Presynaptic cell membrane; Peripheral membrane protein. Note=Localized to presynaptic structures.
Protein: PFPA1_ARATH
Sequence: MDSDFGIPRELSPLQQLRSQYKPELPPCLQGTTVRVELGDGTTVAEAADSHTMARAFPHTLGQPLAHFLRETAQVPDAHIITELPSVRVGIVFCGRQAPGGHNVIWGLFEALKVHNAKSTLLGFLGGSEGLFAQKTLEITDDILQTYKNQGGYDLLGRTKDQIKTTEQVNAALKACTDLKLDGLVIIGGVISNTDAAHLAEFFAAAKCSTKVVGVPVTTNGDLKNQFVEANVGFDTICKVNSQLISNACTDALSAEKYYYFIRLMGRKHSHVALECTLQSHPNMVILGEEVAASKLTIFDIAKQICDAVQARAVEDKNHGVILIPEGLIVSIPEVYALLKEIHGLLRQGVSADKISTQLSPWSSALFEFLPPFIKKQLLLHPESDDSAQLSQIETEKLLAYLVETEMNKRLKEGTYKGKKFNAICHFFGYQARGSLPSKFDCDYAYVLGHICYHILAAGLNGYMATVTNLKSPVNKWKCGATPITAMMTVKHWSQDASYTLTSIGRPAIHPAMVDLKGKAYDLLRQNAQKFLMEDLYRNPGPLQYDGPGADAKAVSLCVEDQDYMGRIKKLQEYLDQVRTIVKPGCSQDVLKAALSVMASVTDVLTTISSNGGQ
What is the function of this protein?
Regulatory subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase.
What are the official names of this protein?
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha 1, PFP 1, 6-phosphofructokinase, pyrophosphate dependent 1, PPi-PFK 1, Pyrophosphate-dependent 6-phosphofructose-1-kinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNUC_HAEDU
Sequence: MQIKPLTPIDRSSKTSEILVQLKNIEVTFAEKQALQNINLTIYKNSITTIVGPNGGGKSTLLKVLLKLLKPSQGQVIHQPGLKIGYVPQKLHLDHSMPITVKKFLSLKPNCSTPSIAAALTLFSIEHLAQNSMQKLSGGELQRVLLARAILDRPQLLVLDEPMQGVDISGQTELYQLLTQTRTWLNCAIIMVSHDLNIVMANTDEVLCVNKHICCAGSPELVSNDPNFIHFFGDQFAKNVAFYSHRHNHHHNLHGDICKGKCEC
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TNSA_ECOLX
Sequence: MAKANSSFSEVQIARRIKEGRGQGHGKDYIPWLTVQEVPSSGRSHRIYSHKTGRVHHLLSDLELAVFLSLEWESSVLDIREQFPLLPSDTRQIAIDSGIKHPVIRGVDQVMSTDFLVDCKDGPFEQFAIQVKPAAALQDERTLEKLELERRYWQQKQIPWFIFTDKEINPVVKENIEWLYSVKTEEVSAELLAQLSPLAHILQEKGDENIINVCKQVDIAYDLELGKTLSEIRALTANGFIKFNIYKSFRANKCADLCISQVVNMEELRYVAN
What is the function of this protein?
Required for Tn7 transposition.  Forms the transposase, together with TnsB (PubMed:8947057).  TnsA executes the 5'-DNA strand breakage reaction (PubMed:10704304).  TnsABC and TnsD promote high-frequency insertion of Tn7 into a specific target site known as ATT-Tn7 whereas TnsABC and TnsD promote low-frequency insertion into many different sites.
What are the official names of this protein?
Transposon Tn7 transposition protein TnsA, Restriction enzyme-like endonuclease TnsA.
Protein: GPA1_ORYSI
Sequence: MGSSCSRSHSLSEAETTKNAKSADIDRRILQETKAEQHIHKLLLLGAGESGKSTIFKQIKLLFQTGFDEAELRSYTSVIHANVYQTIKILYEGAKELSQVESDSSKYVISPDNQEIGEKLSDIDGRLDYPLLNKELVLDVKRLWQDPAIQETYLRGSILQLPDCAQYFMENLDRLAEAGYVPTKEDVLYARVRTNGVVQIQFSPVGENKRGGEVYRLYDVGGQRNERRKWIHLFEGVNAVIFCAAISEYDQMLFEDETKNRMMETKELFDWVLKQRCFEKTSFILFLNKFDIFEKKIQKVPLSVCEWFKDYQPIAPGKQEVEHAYEFVKKKFEELYFQSSKPDRVDRVFKIYRTTALDQKLVKKTFKLIDESMRRSREGT
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  May function in a signal transduction pathway required for normal growth and development of internodes, leaves, panicles and seeds.  Involved in gibberellin signal transduction.  Involved in R gene-mediated disease resistance.  Functions upstream of the small GTPase RAC1 in the early steps of signaling.  Involved in brassinosteroid response.  May not be a signaling molecule in BRI1-mediated perception or transduction.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-1 subunit, GP-alpha-1, Protein Dwarf1.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RSMC_ACIBC
Sequence: MDPRSEVILRQHDYLKGRVLLINAPNDALVSQLPTEIDASVWTWNYADYQGFLNAGATAHFSVEFPLQEFDQAIIFVPKSKELLNYILHVVMSHLKIDQSVFLVGEKKGGVERAAKQLQSFGKILKLDSARHCQLWHLKIEKTEKIKPLESWLKTYTVQVNEQELTICALPGVFSQTHLDVGTAVLLPYLNQVKSGRIADFGCGAGIISCYLAKANSSNIIHALDIDAFALQSTEMTFSRNGIGSDQLRLQPVTGIADAPTELDAIVSNPPFHQGIHTNYDASEGLCQNAKKHLKASGELWIVANRFLNYPILIEKHFGQCEIKTDLQGFKVLYACA
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADB_METST
Sequence: MKTLSDISESVLIPTNSSLDKLLGGGIEKGCITQFYGPPGSGKTNIALKILYEATKNGSKAIYMDTEGGLSLERIQQIAGTDFGSISKNIYILEPKSFDEQILDIQNIEDILKKDKSIDMLIIDSIVALYRVEDGDPSEINKRLGRLMAKLLRLSREYNVAIVITNQIYSPFDSDDLIIEPIGGTVLKYWSKIIIEIEKSVDSLKRTATLQRHKTKAPGQSIKFEIIDRGII
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  May regulate the cleavage reactions of the branch-structured DNA.  Has a very weak ATPase activity that is not stimulated by DNA.  Binds DNA but does not promote DNA strands exchange.
What are the official names of this protein?
DNA repair and recombination protein RadB.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
Protein: NUSB_RHOJR
Sequence: MSGTHKKLGARHKARKRAVDFLFEAEARDLDPVDLATERAELSGKDDSVAPVAPYTVTVVTGVAENLDRLDEVIRSHLQDWTLERLPAVDRAILRIAVWELFHATDVPPVVAVDEAVELAKQLSTDESPGFVNGILGQVVLVAPQVRSAAAATSRRTETAGGESNDAGS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: IF2_LATSS
Sequence: MGKKRIYELAKEINVASKDILETANKKGYDLKNHMATIDDNQEKTLRAAFQTKATPAASKPATPAAPKASEKSESGKIKINKTAIRRRPEADKKPAQHSNNRPQANANRNGQASNGQNRTNNARPNNNSARPNNSRPNTNSRPNNNSQNRSTSANHPMSLQEQISQANARRQRTQERIQQQREQREADEKKRREQANRPRPTRNNASNNRPSNGKPTNGARPTTNSPRPTVTKDGRPLGSSRPNNNNSARPNTTNNRPTNSRPATTPSRPVSAQEMQQKMQANTVSASKPASNNTASKPKNFGPDKKRGGGYNSYGNSQQRFNKKRKKTRKQQLAEQNAAKKEMPQRKERPLPEVLVFSEGMNVADIAKKIHREPAEIIKKLFMLGIMVNMNQSLDKDTIELLATDYGIEAEQKVEVDIADIDSVFETEAKSDANLVSRPPVVTIMGHVDHGKTTLLDNLRNSHVTDGEAGGITQHIGAYQTKLNDRLITFLDTPGHAAFTNMRARGADITDIIILVVAADDGVMPQTIEAINHAKAAKAPIIVAVNKIDKPGANPDHVMEQLMGYGLVPEDWGGDTIFVKISAKTGENIDDLLEMVLLEADVLELKANRDQKAVGTVIEARLDKGKGPVASLLVQQGTLRIGDPIVVGNTFGRVRVMTNDRGRRVKEVFPSEPVEITGLNDVPQAADRFVVFEDEKTARAAGEERAKRALLKERSRSNPVTLDNLFETMKQGELKEVGVIIKADVQGSTEALAGSLRKIEVEGVRVNIIHEAVGAINESDVTLAAASNAIIIGFNVRPTPQAKIQADAEQVDIRLHRIIYKAIEEIEAAMKGMLEPVYEEKVTGQLTVRETYNVSKIGTIAGCIVDTGVIRRDSGVRLIRDSIVIYEGKLSSLKRFKDDVKEVKTGFECGVTIEDYNDIKIDDQIEAYVMEEVPVK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_CHLTA
Sequence: MTHKISVLHQDKKFDFSLRPKKLTEFCGQKQLKERLDLFLRAAVQRNEVPGHCLFYGPPGLGKTSLAHIMANTIGKGLVIASGPQLLKPSDLIGLLTGLQEGDIFFIDEIHRMGKAAEEYLYPAMEDFKVDITLDSGPGARSVRLDLAPFTLVGATTRAGMLSEPLRTRFAFTGRVDYYTDEDLVSILSRSSQLLSIEANQETLLEIARRARGTPRLANNLLRWVRDFAQMREGNCINSAVAEKALAMLLIDNLGLNEIDIKLLSVMIDFYQGGPVGMKTLAMAVGEDVRTLEDMYEPFLILKGLVQRTARGRVATPLAYEHLNRNPKDRWGEE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RL18_GEOSM
Sequence: MSSLAQKQVARLKRQTRVRKKITGSPARPRLNVFKSARHIYAQLIDDTTGATLASASTLLGDVAEGLSYTGNIEAATKVGAAIAKKALEKEITAVVFDRNGFLYHGRIKALADAARENGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GLPD_PSETO
Sequence: MNPSTLPAPPLAEVYDVAVIGGGINGVGIAADAAGRGLSVFLCEKDDLASHTSSASSKLIHGGLRYLEHYEFRLVREALAEREVLLAKAPHIVKQMRFVLPHRPHLRPAWMIRAGLFLYDHLGKREKLAGSKSLKFGANSPLKSEITKGFEYSDCWVDDARLVVLNAMAAREKGAHIHTQTRCISAHRSNGLWEMNMERADGSLFSIRARALVNAAGPWVAKFIRDDLKLDSPYGIRLIQGSHLIVPRLYEGAHAHILQNEDQRIVFTIPYLNHLTIIGTTDREYTGDPAKVAITEGETDYMLKVVNAHFKKQLSRDDIVHTYSGVRPLCNDESDNPSAITRDYTLALSGGNGEAPILSVFGGKLTTYRKLAESAMAQLAPFFTQMRPSWTAKASLPGGENMTTPERAGRRHPRQIRLGTERDAPRRWATTYGSRTWRLLEGVQALADLGDHLGGGLYTREVDYLCAEEWATQPQDILWRRTKLGLFTTAEEQDNVQRYLSKVGQTRAKIEAA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6308_DICDI
Sequence: MKPFNELGICILNGYIFVFVYFDFNFNYIINEIIITIYSVEI
What are the official names of this protein?
Putative uncharacterized transmembrane protein DDB_G0284993.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ABDH_ECOHS
Sequence: MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAAVRAADAAFAEWGQTTPKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINILFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHTASSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVSKAVEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTLFDNEEQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVKH
What is the function of this protein?
Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA).  This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal.  Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Gamma-aminobutyraldehyde dehydrogenase, ABALDH, 1-pyrroline dehydrogenase, 4-aminobutanal dehydrogenase, 5-aminopentanal dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
Protein: RPPH_PROMH
Sequence: MIDDDGYRPNVGIVICNRQGQVLWARRYGQHSWQFPQGGINPGESPEQAMYRELFEEVGLSRKDVKILASTRNWLRYKLPKRLVRWDTKPVCIGQKQRWFLLQLTSNDKDINVQQSKTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFAPVVMPLQEQVSMSRPSYGYRRKRY
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RK32_ORYSA
Sequence: MAVPKKRTSMSKKRIRKNLWKKKTYFSIVQSYSLAKSRSFSGVSEHPKPKGFSRQQTNNRVLG
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PGA7_CANAL
Sequence: MHFIFYLILLVSAADYGNFGTYPKVPKTASINGFADPIYDLLPDCAKECVKFSTSNTPCPYWDTGCFCVMPQWAGLVGQCVAQKCKGEDVASARFLATSLCSVVGANTWMMPASISSMLSTAAGDAKEVTTIEGKTAKSWVTAPGSAAGSVVSETGSASETGSSESAQSTTTGSSSTGSSSTDSSSSSSSSPSSSANFAVLQTGGIGSVILGFMMYLLV
What is the function of this protein?
GPI-linked hyphal surface heme-binding protein involved in heme-iron utilization (PubMed:25275454, PubMed:27617569).  Heme transfer occurs between PGA7, RBT5 and CSA2 supporting a model in which the 3 CFEM proteins cooperate in a heme-acquisition system and form a cross-cell wall heme-transfer cascade (PubMed:25275454, PubMed:27617569).  The ability to acquire iron from host tissues is a major virulence factor of pathogenic microorganisms.  Required for biofilm formation (PubMed:25275454).
What are the official names of this protein?
GPI-anchored hemophore PGA7, Predicted GPI-anchored protein 7, Repressed by TUP1 protein 6.
What is the protein family that this protein belongs to?
Belongs to the RBT5 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell membrane; Lipid- anchor, GPI-anchor.
Protein: RL35_TOLAT
Sequence: MPKMKTDRGAAKRFKKTGSGGFKCKHANKRHILTKKTTKRKRHLRAPGMVAKPDLARVSAMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL34_BUCA5
Sequence: MKRTFQPSILKRNRSHGFRIRMATKNGRYILSRRRAKLRTRLTVSSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.