PharMolix/UniProtQA huggingface dataset:
Protein: CRSP1_BOVIN
Sequence: MGFWKFPPFLVLSILVLYQAGMFHAAPFRSVFDGRFDPATLDEEESRLLLAAMVNDYEQMRARESEKAQKTEGSRIQKRACNTATCMTHRLAGWLSRSGSMVRSNLLPTKMGFKIFNGPRRNSWF
What is the function of this protein?
Stimulates cAMP production in porcine kidney cell line LLC-PK1 via the calcitonin receptor (CT) but not via the CT-like (CL) receptor.
What are the official names of this protein?
Calcitonin receptor-stimulating peptide 1, CRSP-1.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU1_OCEIH
Sequence: MSRIKIFDTTLRDGEQSPGVNLNKAEKLEIAKQLEKYGVDRMEAGFPASSKGDFESVKQIAETIKSSSVIALARAVKSDIDIAYEALKGAEKPAIHIFLATSPIHMTYKLKKSPEQVIETAVNMVTYAKERFDEIEWSAEDATRSDWNFLAQIIEKVIEAGATVINLPDTVGYTTPEEYGKLFRFIKETVPNINQVALSCHCHNDLGMAVANSIAAVENGATQVEGTINGIGERAGNAALEEVAVALKIRSDYYPFETGLILKETKRTSDLVAKLTGMYVQANKAVIGRNAFSHESGIHQDGVLKNTETYEIITPEMVGVSSNTLFLGKHSGRHAFKDKLKEFGVELSEEELKTAFEQFKLLTDQKKEVTDDDLYTILMDIKTDSTVVDKYKLIQFGVSYDTAATPKANVILESPNGSLIEATQQGNGSVEALYKTINYLIAENITLVDYQINSVGGGKDALAESHVQIIINGETINGRGSAQDVLQASAVAFIQAVNRYYVQKKANLTRLVYES
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: MLF2_HUMAN
Sequence: MFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPGTRPASRRMQQAGAVSPFGMLGMSGGFMDMFGMMNDMIGNMEHMTAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSRFRQQRPLEFRRLESSGAGGRRAEGPPRLAIQGPEDSPSRQSRRYDW
What are the official names of this protein?
Myeloid leukemia factor 2, Myelodysplasia-myeloid leukemia factor 2.
What is the protein family that this protein belongs to?
Belongs to the MLF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KITH_EBVB9
Sequence: MAGFPGKEAGPPGGWRKCQEDESPENERHENFYAEIDDFAPSVLTPTGSDSGAGEEDDDGLYQVPTHWPPLMAPTGLSGERVPCRTQAAVTSNTGNSPGSRHTSCPFTLPRGAQPPAPAHQKPTAPTPKPRSRECGPSKTPDPFSWFRKTSCTEGGADSTSRSFMYQKGFEEGLAGLGLDDKSDCESEDESNFRRPSSHSALKQKNGGKGKPSGLFEHLAAHGREFSKLSKHAAQLKRLSGSVMNVLNLDDAQDTRQAKAQRKESMRVPIVTHLTNHVPVIKPACSLFLEGAPGVGKTTMLNHLKAVFGDLTIVVPEPMRYWTHVYENAIKAMHKNVTRARHGREDTSAEVLACQMKFTTPFRVLASRKRSLLVTESGARSVAPLDCWILHDRHLLSASVVFPLMLLRSQLLSYSDFIQVLATFTADPGDTIVWMKLNVEENMRRLKKRGRKHESGLDAGYLKSVNDAYHAVYCAWLLTQYFAPEDIVKVCAGLTTITTVCHQSHTPIIRSGVAEKLYKNSIFSVLKEVIQPFRADAVLLEVCLAFTRTLAYLQFVLVDLSEFQDDLPGCWTEIYMQALKNPAIRSQFFDWAGLSKVISDFERGNRD
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Note=Localizes to the centrosome and more precisely to the periphery of the centriole, tightly encircling the tubulin-rich centrioles.
Protein: TERS_BPLP2
Sequence: MQTQKGGRPTILPKMYEEPLFSQIIDKIESGCNDREIYTSLHCSAKTFRKWRDDNIKAYDEAKSIARGNLLELAESALASKLTVRTLKETETIYDADGNVEKVKVKEKELDKDSLVAMMVAKAGNPELYNPTEWRRLQQEESSAHDLKAKIEELDDYKLSKYKTPEIEVPEGFE
What is the function of this protein?
Probable terminase small subunit.  The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit and a large terminase subunit.  Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine.  Once the capsid is packaged with the DNA, the terminase complex is substituted by the connector proteins gp15.
What are the official names of this protein?
Terminase small subunit, Gene product 1, gp1.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus terminase small subunit family.
Protein: PYRG_KLEP7
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMTRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLAGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLTCPEANLAEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMENANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGEPTITERHRHRYEVNNMLLKPIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEYQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: KCY_ACIBY
Sequence: MTVQIITIDGPSGSGKGTLAAKLAAYYQFHLLDSGALYRLLGLSLHKHDLLEKLDSHLDMCVNYARQLNIKFETSAEGTLVFLDGEDVTQTIRTERVGEYASKVAAIPELRQALFERQRAFAQTPGLVADGRDMATSIFPEANAKIYLTASAESRAERRVKQLQGMGLDAKINDILANIQARDKRDMEREVAPLKPAADAYIIDSSELTIDQVFKLMVDYVNSRTVSN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_FRASN
Sequence: MATRLFTSESVTEGHPDKIADQVSDSILDAMLKDDPKSRVAVETMITTGQVHVAGEVTTKTYVDIASVVRERILEIGYDSSKKGFDGASCGVSVSIGSQSPDIAQGVDTAHEARVEGSTEDDLDRQGAGDQGLMFGFACDETPELMPLPIALAHRLARRLSAVRKDGQVGYLRPDGKTQVTIEYEDGKPVRLDTVVVSSQHAADIDLDTLLAPDVAEYVVEPELALLEISTEGRRLLVNPTGRFEIGGPMGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLASRCEVQVAYAIGKAHPVGLFVETFGTGKVPDAQIQDAVTQVFDLRPAAIVRDLDLLRPIYAQTAAYGHFGRPELDFTWEATSRADALTAAVKG
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_THIDA
Sequence: MKTTFLDFEQPIAELEAKIEELRFVQDDSALDISEEIRRLQKKSQALTKDIYAKLNAWQVSQVARHPQRPYTLDYIQGLFTDFVELHGDRAYADDAAIVGGMARFNGEPVMVIGHQKGRDTKEKIFRNFGMPRPEGYRKALRLMRLAEKFRLPILTFIDTPGAYPGIGAEERGQSEAIARNLYVMAELQTPIVCTIVGEGGSGGALAIGVGDRTLILQYSTYSVISPEGCASILWKSADKASVAAETLGITADRLKANGLVDRIIEEPLGGAQRDWDAMFQSMRRALTDTLAELRKQPTEAMLGARYQRLRAYGSFKEAPAR
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_STAAM
Sequence: MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMVRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: Y498_MYCTO
Sequence: MRPAIKVGLSTASVYPLRAEAAFEYADRLGYDGVELMVWGESVSQDIDAVRKLSRRYRVPVLSVHAPCLLISQRVWGANPILKLDRSVRAAEQLGAQTVVVHPPFRWQRRYAEGFSDQVAALEAASTVMVAVENMFPFRADRFFGAGQSRERMRKRGGGPGPAISAFAPSYDPLDGNHAHYTLDLSHTATAGTDSLDMARRMGPGLVHLHLCDGSGLPADEHLVPGRGTQPTAEVCQMLAGSGFVGHVVLEVSTSSARSANERESMLAESLQFARTHLLR
What are the official names of this protein?
Uncharacterized protein MT0518.
What is the protein family that this protein belongs to?
To M.leprae ML2432 and S.coelicolor SCO3347.
Protein: DUG1_SCHPO
Sequence: MKMSLDKLYEVIDKKKDEFVTRLSRAVSIPSVSADVTLRPKVVEMADFVVSEFTKLGAKMEKRDIGYHQMDGQDVPLPPIVLGQYGNDPSKKTVLIYNHFDVQPASLEDGWSTDPFTLTVDNKGRMFGRGATDDKGPLIGWISAIEAHKELGIDFPVNLLMCFEGMEEYGSEGLEDLIRAEAEKYFAKADCVCISDTYWLGTKKPVLTYGLRGVCYFNITVEGPSADLHSGVFGGTVHEPMTDLVAIMSTLVKPNGEILIPGIMDQVAELTPTEDSIYDGIDYTMEDLKEAVGADISIYPDPKRTLQHRWRYPTLSLHGIEGAFSGSGAKTVIPAKVIGKFSIRTVPNMESETVERLVKEHVTKVFNSLNSKNKLAFNNMHSGSWWISSPDHWHYDVGKKATERVYGITPDFVREGGSIPVTVTFEQSLKKNVLLLPMGRGDDGAHSINEKLDLDNFLKGIKLFCTYVHELASVSP
What is the function of this protein?
Catalytic component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond.  Has a Gly-Cys dipeptidase activity.
What are the official names of this protein?
Cys-Gly metallodipeptidase dug1, GSH degradosomal complex subunit DUG1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACG_STRP6
Sequence: MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWYTAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAECHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVNYAELCFKEFSEVNYWTTFNEIGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHALPTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDLREEDFVALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRRKAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDDGRIDYVKKHLEVISDAISDGTNVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERYPKKSAYWYKKVAETQVIE
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: ASTC_ECOUT
Sequence: MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPPDIRHAAYNDINSASALIDDATCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNALLIFDEVQTGVGRTGELYACMHYGVTPDLLTTAKALGGGFPVGALLATEECASVMTVGTHGTTYGGNPLASAVAGKVLDLINTPEMLNGVKQRHDWFVERLNSINHHYSLFSEVRGLGLLIGCVLNADYAGQAKQISQEAVKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAAACEHFVSRGSS
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, SOAT, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: MNMA2_THEPX
Sequence: MEINNRVAIGMSGGVDSSVAAYLLKKQGFDVIGLTMRVWVDHEAKAFDSDKSCCSLKATQDAKKVAEILGIPHYTVDLSKIFYDKIVNYFVNEYLKGRTPNPCVLCNRQIKFGELLEKAFELGAYYIATGHYVRKEYDEKTKRYLLKKGIDSSKDQSYVLYRLTQKQLEHALFPLGNYKKEEIRALAEELKLPVAKKPESQEICFIPDNDYSGLIKRQVKDEIKPGEFRDVHGKFLGYHKGIIHYTIGQRRGLGLSSDRPLYVVDIDVKNNVVVVGHQEDVWGEELISSNNNFISIEKLEKEMKVTAKIRYTAKEEEAIIKPYEEDKVLVKFLKPQRAITPGQSVVFYDKDVVVGGGIIERKLK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 2.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDB_LACLM
Sequence: MEILYTEITQDLTEGLLEIALEELEKNRKVYYIVPSSMSFEKEKEILERLAKGSDTAVFDLLVTRFKQLPYYFDKREKATMKTELGTVGLSMLFRRVLRSFKKDEIPLYFSLQDSAGFLEMLIQLRAELLTANLSVENLPDNPKNQELKKILAKFEAELSVEYANYSEFGDFTNRLVDGEFDQQLKDVTIIIDGYTRFSAEEELFIESIQEKVARFVVGTYSDENSLTAGSETIYVGTSQMITRFRNKFPVELRKIASSAVNEVYSKLTRILDLDSRFVITDEKIELKAEDEKYFRIWEAENQKVEIERVAKEIRQKIIQGAFFKDFTVLVGDPAAYEITLKEVFDLYEIPFFYAQEESMSQHPLVIFFESLFAIKKNNYRTDDVVNLLKSKVYTDANLDEEVIDYFEYYVQKYKISGRKKFTEEFIESEFSQIELVNEMREKLLGSESPLQVFLGNNRKKTGKKWVSDLQGLLENGNVMTNMNAYFSAAELQNEHQMADKHEQVWQMLISTLNEFLAVFSDEKLKSVEFLDILLAGLKNAKYRQIPANVDVVNVKDYELVEPKTNKYIYAIGLSQTNFPRIKKNSTLLSDEERLEINQTTDENQFIEQLNVANYQKNQFTVLSLINSAKESLVLSMPQIMANEQGEFSPVFQLFLKDADEKILQKIQGVNLFESLEHIGNSRSVIAMIGQIERELVESEETSEDKRVFWSSIFRILVKSNADFQKILLDLAKDIDTVNLAPDTLEQIYGDKIYASVSSFERFYNCEYQYFLENTLSLETFENIDINSKIVGNFFHEVFEKVMKETDLSAENFDEKLTLVLQEVDKNYSRYFTQDATARFTWSNLEEIVRQTATVLKATVSTDELKTLLTESSFGLPKSELGNFSVDDIYLRGRIDRLDQLSTDYLGAIDYKSSAHSFKLQEAYDGLSLQFMTYLDVIKQAFPNQKIWGALYLQFKNQPINLSEINQLSEIANILKESMRYEGLVLEDAAEQIKGIENIALKKTNIYNEEEFEQLLKLNEEHYRAAGQRLKKGKIAINPIMKRSEGIDQSGNVRGCRYCPLKSICRFEANIHMNEHSREIGQKSQAEILAELKGEERDE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the L. lactis chi site (5'-GCGCGTG-3'), which stimulates homologous recombination.  This subunit has 5'->3' exonuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: ATPF1_VIBC1
Sequence: MNINATLLGQAISFALFVWFCMKYVWPPLMQAIEERQKKIADGLQAAERAAKDLDLAQANASDQMKEAKRTATEIIDQANKRKSQIIDEAREEAQAERQKILAQAEAELEAERNRARDELRKQVATLAVAGAEKILERTIDKDAQKDILDNITAKL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TEA2_SCHPO
Sequence: MSSSSSKPVNTGLVTPRRYSTMTGIRTGPSQSGTGSIPYSPTSPLSRNFSNYSIPMLRSNSTQTNVNGPTAFDLGVTEKLMSPGTLDRYTRPALYPSKDLDYLKNEYVNYESTTSQQTNSKGLKESNFVGSGIITSIRIRPIGKNQGVWSHGKLSNDPYGREYIRQQTSTSSSTIQQEYLFNNVFGMESKNYDIYKRSVKSVVRNVFSGYNGIVFAYGMTGTGKTYSMQGTENEPGIIPLAMNDLFEMVENNSDDDTFQIRISYLEIYNERIRDLIGNSDEEPRIRENASGEVNVTPLTRVLVTSPEEVSQVIEQCNAIRKTAATDFNTYSSRSHAILQVFLIRNNPTAHTSQISSLSLVDLAGSERASAHHERRKEGAFINKSLLTLGTVISRLSAAANPSLTSNSGHIPYRESKLTRLLQQSLSGQSQISLLATISIESNHTMETTNTLKFASRAQNLPQDIRQAEAVTNVQAELASLHSALEKNAQEVEYYASLVKQLTSDLEERDTYIAMLEAERSQGTAISRARLRMEELLSDHNFEIADLRDELQDKEQIIYALRYAQKQRDIADFNQSLAKFPHKILKKNVTRGSRSSSDQFSNETKTEILPDDQQQSKKDSVTQETQLLS
What is the function of this protein?
Promotes microtubule growth, possibly through interactions with the microtubule end, and is important for establishing and maintaining polarized growth along the long axis of the cell.  Acts as a kinesin motor protein that moves along microtubules and is required for proper localization of tea1 and tip1 to the cell tips and microtubules, respectively.  ATPase activity stimulated via interaction with mal3.
What are the official names of this protein?
Kinesin-like protein tea2, Kinesin-like protein 4, Tip elongation aberrant protein 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Localized in large clusters at cell tips and also in punctate dots within the cell that are coincident with the ends of cytoplasmic microtubules.
Protein: RIPK4_HUMAN
Sequence: MEGDGGTPWALALLRTFDAGEFTGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICREPVGLVMEYMETGSLEKLLASEPLPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQGNGLNGELIRQVLAALLPVTGRWRSPGEGFRLESEVIIRVTCPLSSPQEITSETEDLCEKPDDEVKETAHDLDVKSPPEPRSEVVPARLKRASAPTFDNDYSLSELLSQLDSGVSQAVEGPEELSRSSSESKLPSSGSGKRLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLLRRSKT
What is the function of this protein?
Involved in stratified epithelial development.  It is a direct transcriptional target of TP63.  Plays a role in NF-kappa-B activation.
What are the official names of this protein?
Receptor-interacting serine/threonine-protein kinase 4, Ankyrin repeat domain-containing protein 3, PKC-delta-interacting protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: DHE3_PIG
Sequence: MYRCLGEALLLSRAGPAALGSAAADSAALLGRTRGQPATAPQPGLAPPARRHYSEAAADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGTILGFPKAKIYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT
What is the function of this protein?
Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate.  Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (PubMed:8240242).  Plays a role in insulin homeostasis (By similarity).  May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).
What are the official names of this protein?
Glutamate dehydrogenase 1, mitochondrial, GDH 1, Membrane protein 50, MP50.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion. Endoplasmic reticulum. Note=Mostly translocates into the mitochondria, only a small amount of the protein localizes to the endoplasmic reticulum.
Protein: USH_DROME
Sequence: MLSSNTRGDCSDTAEEMTVDSRDSKDLSAQDIGEQKQQQMEDQLEDQLNDSRDPQNNNNNIDDDADEDAEFEEPEKANPQQDQDLGETEMEQEHDLQQEDLQQELPANSPSTPPRSPSSPQLIPKLEQPATPPSEPEASPCPSPSPCPTPKYPKVRLNALLASDPALKPDAKELTLPDSRLLAPPPLVKPDTQAQPEVAEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRIKDTDEAGSDKSGAGGSGATAGDAAGLTGGSTEPPAKMARTGKQYGCTQCSYSADKKVSLNRHMRMHQTSPAAPTLAGLPSLLQNGIAPPGVTPNPMEDSSSQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPDASPGAGSGPGSAGGSIGVSAQAATPGKLSPQARNKTPTPAMVAVAAAAAAAAASLQATPHSHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTIKPLATALVGATLEPERPSAPSSAAEATEAKSSPPEPKRKEAGLTRESAPLDLSLRRSPITLNSLSLRQRQLRNALLDVEEVLLAGVGTGKENVETPRGGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPGLNVAVPHLLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGSSGAAAFPPASLPAQTSSGNPGSGGSAGGAQQPQIYVKKGVSKCMECNIVFCKYENYLAHKQHYCSARSQEGASEVDVKSAVSPSIAGAGGLGAGAAEAASSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAVAAPAATPTDPGQLGMPKEKCGKCKTLHEIGLPCPPPVANPLAAPTVNPQPATNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEELYMTCIFEEDASALSQELVTPTGASTTTGHDSMDHPSQMFNCDYCNYVSTYKGNVLRHMKLMHPHVAINSPSISPDTRDQDVTSNPTTNQHSNSDVSNGEAPSFHIKSEPLDPPPTVNLVHENNNSPIATPHIKAEPIEVGADAAPGGLVPPMTSPLGNSSSVAAAAAAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPIRPEASDSPSPNHLGGGVAVGLGIGGLVGGHGQQKNKENLQEAAI
What is the function of this protein?
Transcription regulator that modulates expression mediated by transcription factors of the GATA family such as pnr and srp.  Represses transcription of proneural achaete-scute complex (AS-C), which is usually activated by pnr.  Involved in cardiogenesis, blood, and eye development.  During hematopoiesis, it is required to restrict the number of crystal cells, probably via its interaction with the isoform SrpNC of srp.  Negatively regulates expression of sr.  Probably acts by interacting with the GATA-type zinc finger of proteins such as pnr and srp, possibly antagonizing the interaction between the GATA-type zinc finger and some cofactor.
What are the official names of this protein?
Zinc finger protein ush, Protein U-shaped.
What is the protein family that this protein belongs to?
Belongs to the FOG (Friend of GATA) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTL_SYNY3
Sequence: MIQVLDRQLVDLIAAGEVIDSPLAVVRELVENALDAGADRILVRVWWDQWRLEVLDNGQGMDVTELKTSVLPHATSKISTQADLQRIKTLGFRGEALHSLAQVARLTISSRSVASPGCGWRITYSPQGSPEQIEPVAIAMGTRVEVRQLFANFPQRRQAFAKSQQFWRPMVTYLQQLALCHPQVTWQLWQDERLRLSLSPGPNPEAILLQCLKSLQAGQLGYTQQSLSLPVDLENQATSAQLSLTFGYPDRCHRPRPDWLIIAINGRPVNVPELTQTILAVFHRTLPRQRYPLCFAHWQLPPQCIDWHRHPAKTEIYLQDLPHWQGQLKTLLHQSLAILGNDAPPRLNQLLKAAEPKGVYQLQGASSLTETVLGYPKAFKAIAQVCQTYVVVEHDQGIWLVEQHVAHERVLFEQLQRHWQCLPLEQPLVLQGFNPEQVERLQNLGLEIDPFGEDIWAVRSLPALLQGQEEIIAILRELSQVFSLSTAQAAIACRSAIKNGMELDRIAINKLIEQWQQCDNPHTCPHGRPIYLALDESSLARFFRRNWLVNPKTSGS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: EFTU_STAAT
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVAQSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_LOTJA
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.