PharMolix/UniProtQA huggingface dataset:
Protein: NRAM_I77A4
Sequence: MNPNQKIITIGSVSLTIATICFLMQIAILVTTVTLHFKQYECDYPANNQAMPCEPIIIERNITEIVYLTNTTIEKEVCPKLVEYRNWSKPQCKITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTIHDRTPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCVTGYDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTKILFIEEGKIVHTSPLSGSAQHVEECSCYPRYPGVRCICRDNWKGSNRPVVDINVKDYSINSSYVCSGLVGDTPRNNDRSSSSYCQNPNNEKGTHGVKGWAFDDGNDVWMGRTISEDSRSGYETFKVIGGWSTPNSKLQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGREQETRVWWTSNSIVVFCGTSGTYGTGSWPDGADINIMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: MIRO1_CHICK
Sequence: MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQNDEQLYHEISQANVICIVYAVNNKNSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNRSELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFRISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKNVSDGVADNGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLELTPEYLFPLLKIPPDCTTELNHHAYLFLQSIFDKHDLDRDCALSPDELKDLFKVFPYMPWGPDVNNTVCTNGKGGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILAEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVVGMKGCGKSGVLQALLGRNLMRQRQIRAEHKSYYAINTVYVYGQEKYLLLHDVSDSEFLTDAETICDVVCLVYDVSNPKSFEYCVRIFKQHFMDSRIPCLVVAAKSDLHEVRQEYSISPAEFCKKHKMPPPQAFTCNTVDMPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGATVFAFLGFAMYKALIKQR
What is the function of this protein?
Mitochondrial GTPase involved in mitochondrial trafficking.  Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity).
What are the official names of this protein?
Mitochondrial Rho GTPase 1, MIRO-1, Ras homolog gene family member T1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial Rho GTPase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Protein: U85A4_ARATH
Sequence: MEQHGGSSSQKPHAMCIPYPAQGHINPMLKLAKLLHARGFHVTFVNTDYNHRRILQSRGPHALNGLPSFRFETIPDGLPWTDVDAKQDMLKLIDSTINNCLAPFKDLILRLNSGSDIPPVSCIISDASMSFTIDAAEELKIPVVLLWTNSATALILYLHYQKLIEKEIIPLKDSSDLKKHLETEIDWIPSMKKIKLKDFPDFVTTTNPQDPMISFILHVTGRIKRASAIFINTFEKLEHNVLLSLRSLLPQIYSVGPFQILENREIDKNSEIRKLGLNLWEEETESLDWLDTKAEKAVIYVNFGSLTVLTSEQILEFAWGLARSGKEFLWVVRSGMVDGDDSILPAEFLSETKNRGMLIKGWCSQEKVLSHPAIGGFLTHCGWNSTLESLYAGVPMICWPFFADQLTNRKFCCEDWGIGMEIGEEVKRERVETVVKELMDGEKGKRLREKVVEWRRLAEEASAPPLGSSYVNFETVVNKVLTCHTIRST
What are the official names of this protein?
UDP-glycosyltransferase 85A4.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: RECF_LACE2
Sequence: MIVESVELKDFRNYEFLDMNFNEHVNIIYGDNAQGKTNILESIYMCSTSKSHRGSKDREIVRFGEDESHIKLNVLKHGMKYRIDMHLKKNKTKGIAVNGIPIKKAVELFGIINIVFFSPEDLNIIKNGPSERRRFMDMELSQLDKIYLSNLVNYNKVLNQRNKLLKDIAFSPSEQLMQTLDIWDMQLVKYGSLIIKGRKSFIEKINTIISDIHSRLTGGIENIKVCYVPDVDVNDFEEEVRNSRQKDIKYKVTGKGPHKDDLIFLINDNDVRKYGSQGQQRTAALSLKLSEIELVKLVIKDTPVLLLDDVLSELDSNRQNFLINSIGDIQTIVTCTGLEEFINNRMNINKIFKVTDGHVVNEN
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELA_SALTY
Sequence: MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSALRPVINLTGTVLHTNLGRALQAQEAIEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVEEAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPLKRALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLPVDRLPSAAMTFTPHDGRGSRLEALAARWRMLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_STAAM
Sequence: MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: VQ22_ARATH
Sequence: MANPNEWSQFYNNNQTFFTTSTTASTAVTTTTAGDTTSIDSRLSPETGRVTKPTRRRSRASRRTPTTLLNTDTSNFRAMVQQYTGGPSAMAFGSGNTTSAFSLTSSSDPSAGSSQQAPWQYNFQPHAPLQPPQRPYMFSLNNVNPVVGYSNMNNPNTMVSGVFGTVDGSGGGGSAPSSKEATNSNSSSSRLQ
What is the function of this protein?
May function as positive regulator of plant growth.
What are the official names of this protein?
VQ motif-containing protein 22, AtVQ22.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACP_CHLMU
Sequence: MSLEDDVKAIIVDQLGVSPEDVKESSSFIEDLNADSLDLTELIMTLEEKFAFEISENDAEQLRTVGDVIKYIQERQN
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_HYDCU
Sequence: MKHQVAEILSKVIDQFKQEGVLDASFQPRVNVENTRDKSHGDFATNLAMMLTKVVGKPPREVAEMIVARLPESDVIEKVEIAGPGFINFFVLDVAKFDVLPSILEAGETFGECNVGQGRSVLVEYVSANPTGPLHVGHGRGAAYGASVASLLSKAGFRVSREYYVNDAGRQMDILAASTWLRYLQHCGEELTFPSNGYKGDYIFDIAQSLYEEKGDALRKPAENVFEGVADDEVTTADGETLGDKEKHIDDLIEKTKVLLGDEHYRVVFDKALDAILGDIREDLAEFGVEFENWFSERSLMDSGVIDAALEKLQAAGKIYEKKGALWFKSSEYGDEKDRVVVRENGLKTYFASDIAYHFNKLERGFDVLIDIWGSDHHGYVPRVKAAMQALDTNPEALEVLLVQFAVLYRGGEKLAMSTRSGQFVTLRELRDEVGADAARFFYVQRKSEQHMDFDLDLAKSKSNENPVYYIQYAHARICQVLSLAEERGYQLDTEMGLANLNRLTQEPEADLATLLAKYPEIIARAALAYEPHQIAYYLKELAHGLHAYYNSTQFIVEYEPLRNARLTLVVAVRQVLQNGLKLLSVAAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_ANOFW
Sequence: MPKGEGKLIAQNKKAHHDYFIEETYEAGLVLQGTEIKSIRAGKVNLKDSFAKVEKGEVFLHNMHISPYEQGNRYNHDPLRTRKLLLHRREISKLIGYTKEQGYTLVPLKLYIKNGFAKLLLGVGKGKKKYDKREDMKKKEAQREVERAFRERQK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GSTU5_ARATH
Sequence: MAEKEEVKLLGIWASPFSRRVEMALKLKGIPYEYVEEILENKSPLLLALNPIHKKVPVLVHNGKTILESHVILEYIDETWPQNPILPQDPYERSKARFFAKLVDEQIMNVGFISMARADEKGREVLAEQVRELIMYLEKELVGKDYFGGKTVGFLDFVAGSLIPFCLERGWEGIGLEVITEEKFPEFKRWVRNLEKVEIVKDCVPPREEHVEHMNYMAERVRSS
What is the function of this protein?
In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC).  May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase U5, AtGSTU5, AtGSTU1, GST class-tau member 5, Glutathione S-transferase 103-1A.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Tau family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: H2AZ_HUMAN
Sequence: MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV
What is the function of this protein?
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  May be involved in the formation of constitutive heterochromatin.  May be required for chromosome segregation during cell division.
What are the official names of this protein?
Histone H2A.Z, H2A/z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
Protein: L2HDH_CAEEL
Sequence: MLNRGTFQVFRGISGPPKKSVDLPKYDLVIVGGGIVGCATARQLLIEKPQLKVALIEKEKELAVHQSGHNSGVIHAGIYYTPGSLKAKLCVEGLDLSYEFFDKEKVPYKKTGKLIVAVEPEEVPRLDALFSRAQTNGCRDIEMIDSSKITELEPHCRGLKALWSPHTGIVDWGYVTKRFGEDFEKRGGKIYTSYPLEKISDNHDPGYPIRVSSGPALAEFETKNLITCAGLQSDRVAALSGCSTDPKIVPFRGEYLLLKPEKRHLVKTNIYPVPDPRFPFLGVHFTPRMNGDIWLGPNAVLAYKREGYSYFSISPSDLLESLSYSGMQKLVKKHFTFGIKELYRGVWIAAQVKQLQRFIPELKLSDVTRGPAGVRAQAMDSAGNLVDDFVFDSGTGKLSPLLMHVRNAPSPAATSSLAIAKMITSEAINRFKL
What are the official names of this protein?
L-2-hydroxyglutarate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the L2HGDH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PMIP_PHANO
Sequence: MLKRLARNNSSPWICSRCLQQSQRQRRFNSTFAATATARDHAPSALYGLSASGKTDDDALRKVFDNASFWESFKRGTSNKKPSGIIGNKYLTHPDGFIDFVTVTIQRCNGVVEKVSRAETIEDFKYMVKDLDKLSDLLCRVIDLADFVRSTHPNRQFQIMAVKAYHTVFQYMNQLNTTPVLYDQLKKASDIPEVFESWTEEERIVARILMEDFARFGIGLDDATRQKLVDLSGEIAEVGSQFVEGMSPETPTLKFESKRLKGLDPNLAKALTKWGETRISTMHHEAQAVLRFVDDAEVRRETYSAVRTAGSSTIARLEKMLKLRAELAQLSGYETFSHMTLENKMAKTPEAVNTFLKALYEDSRPSVLADLHELMELKRGDAHQDNFPNRMNAWDKFYYTQKMLSTMEGAYKQRTADSLSAYFSVGTVLQGISRLFDRLYGVRLVPQETQPGEVWEDGVRRLDVISDTEGHIAVLYCDLFSRPGKTPNPAHFTLRCSREILPAELEEMQHMPHRFSSPIEAATDGMSVSYNASRNSYFQLPTIALICDFSKPSSPRPTLLNIHDVRTLFHEMGHALHSILGRTALQNVSGTRCATDIAELPSVLMEHFAFDPSVLALYARHWDTNAPLPLALLENRLAIDNRNGYSELESQILLAMLDQAYHSNLPLDPAFNSTSVYHNTYTRFASVPEPAGTRWQGFFGHLFGYGATYYSYLFDRAIASRIWKGVFNEGRDGGSLDREKGELYKNEVLRWGGGRDGWVCLAGVLRDGKVGEGGEGAMREVGKWGIDAGK
What is the function of this protein?
Cleaves proteins, imported into the mitochondrion, to their mature size.  While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial intermediate peptidase, MIP, Octapeptidyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: AROA_XANOM
Sequence: MSSNTHHWIARRGTALQGSLAIPGDKSVSHRAVMFAALADGVSQIDGFLEGEDTRSTAAIFAKLGVRIETPSASQRIVHGVGVDGLQPPTGALDCGNAGTGMRLLAGLLAAQRFDSVLVGDESLSKRPMRRVTGPLAQMGARIDTQDDGTPPLRVHGGQALHGIDFVSPVASAQVKSAVLLAGLYAQGETSVTEPHPTRDYSERMLSAFGVDIDFSPGSARLRGGQRLRATDIAVPADFSSAAFFIVAASIVPDSEVVLRAVGLNPRRTGLLAALRLMGADISEENHAEHGGEPVADLRVRYAPLRGAQIPEALVPDMIDEFPALFVAATAASGQTVVTGAAELRVKESDRLAAMATGLRTLGVQVDETPDGATIHGGSIGSGVIESHGDHRIAMAFAIAGQLSSGSVRVNDVANVATSFPGFDTLAQGAGFGLEAAESG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_SYNY3
Sequence: MNIAVVGLSHKTAPVEIREKLSIQEAKLEEALTHLRSYPHIEEVTVISTCNRLEIYAVVTDTEKGVVEITQFLSETGNIPLATLRRYLFTLLHEDAVRHLMRVAAGLESLVLGEGQILAQVRTTHKLGQKYKGVGRLLDRLFKQAITAGRRVRTETDIGTGAVSISSAAVELVHRQVDLSSQKTVIIGAGKMACLLVKHLLAKGATDITIVNRSQRRSQDLANQFPQAQLTLCPLTDMFTAIAAGDIVFTSTGATEPILNCENLTGCVINRKSLMLVDISVPRNVAADVHAMEQVRAFNVDDLKEVVAQNQASRRQMARQAEALLEEEIAAFDLWWRSLETVPTISSLRSKVEDIREQELEKALSRLGSEFAEKHQEVIEALTRGIVNKILHEPMVQLRAQQDIEARKQCLRSLKMLFDLEVEEQFG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: EFTS_SALPK
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNVAFILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVASLEGDVLGSYQHGARIGVLVAAKGADEELVKQLAMHVAASKPEFVKPEDVSVDVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKSVGQLLKEHNADVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_LEPBL
Sequence: MKVRTSVKKICSSCKVIRRKGVIRVICTNPKHKQRQA
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PG10_MYCTU
Sequence: MSWVMVSPELVVAAAADLAGIGSAISSANAAAAVNTTGLLTAGADEVSTAIAALFGAQGQAYQAASAQAAAFYAQFVQALSAGGGAYAAAEAAAVSPLLAPINAQFVAATGRPLIGNGANGAPGTGANGGPGGWLIGNGGAGGSGAPGAGAGGNGGAGGLFGSGGAGGASTDVAGGAGGAGGAGGNAGMLFGAAGVGGVGGFSNGGATGGAGGAGGAGGLFGAGRERGSGGSGNLTGGAGGAGGNAGTLATGDGGAGGTGGASRSGGFGGAGGAGGDAGMFFGSGGSGGAGGISKSVGDSAAGGAGGAPGLIGNGGNGGNGGASTGGGDGGPGGAGGTGVLIGNGGNGGSGGTGATLGKAGIGGTGGVLLGLDGFTAPASTSPLHTLQQDVINMVNDPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNGGQGTIGGVNGGAGGAGGAGGILFGTGGTGGSGGPGATGLGGIGGAGGAALLFGSGGAGGSGGAGAVGGNGGAGGNAGALLGAAGAGGAGGAGAVGGNGGAGGNGGLFANGGAGGPGGFGSPAGAGGIGGAGGNGGLFGAGGTGGAGGGSTLAGGAGGAGGNGGLFGAGGTGGAGSHSTAAGVSGGAGGAGGDAGLLSLGASGGAGGSGGSSLTAAGVVGGIGGAGGLLFGSGGAGGSGGFSNSGNGGAGGAGGDAGLLVGSGGAGGAGASATGAATGGDGGAGGKSGAFGLGGDGGAGGATGLSGAFHIGGKGGVGGSAVLIGNGGNGGNGGNSGNAGKSGGAPGPSGAGGAGGLLLGENGLNGLM
What are the official names of this protein?
Uncharacterized PE-PGRS family protein PE_PGRS10.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
Protein: DSBE_YERPE
Sequence: MKPQSSFNKLMFIPLVLFLLLVVAFLIQLTRNANGEDPTMLESALIGKPVPAFKLESLEQPGKTFDQAVLRDGKPILLNVWATWCPTCRAEHEYLNKLAAQGIRVVGLNYKDDRSKAVQWLNSLGNPYFLSLYDGDGMLGLDLGVYGAPETFLIDGQGVIRYRHAGDLNDRVWQQEILPLYKKYQGGA
What is the function of this protein?
Involved in disulfide bond formation.  Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme.  Possible subunit of a heme lyase (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbE, Cytochrome c biogenesis protein CcmG.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: ZBT43_MOUSE
Sequence: MEPGTNSFQVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFQAHKAVLAASSPYFCDQVLLKNSRRIVLPDVMNPRVFENILLFSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVLCQKLNHGSDHQSPSSSNYNGLVESFELGSGGHTDFPKAQELRDGENEEESTKDELSSQVTEHEYLPSNSSTEHDRLSTEMASQDGEEGTNDSTEFHYTRPLYSKPSIMAHRRWIHVKPERLEQAWDGMDVHAAYDEHQVTESVNTMQTDHSAQPSGAEEEFQIVEKKVEVEFDEQAEGSSYDEQVDFYGSSMEEFSGEKLGGNLIGHKQEAALAAGYSENIEMAMGIKEEASHLGFSATDKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCSVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEAAKAEQNTTEAN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 43, Zinc finger protein 297B.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LGT_HELAH
Sequence: MNAWNTIYERFNPIAFSLGSIEVHWYGLAYACAIVIAFYMALRMIQKDPKRFPVARKDFESYFLWAELGIVLGARIGYILIYEPNSSYYLTHFWQIFNPFDSHGNFIGIRGMSYHGGLVGFLIASYLYNRKDLKKLLIYLDLIAISLPLGYVFGRIGNFLNQELVGRIVPKDSHLGQMIGIVVDHELRYPSQLIEAFLEGVIVFLMVMWAKKHTKTHGLLIVVYGLGYSLMRFIAEFYREPDSQLGVYFLNLSMGQILSLFMVIVSLGILLYATKNSKKIKEN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KUP_POLNA
Sequence: MTSQKSSLAVLTVGAIGVVYGDIGTSVLYAIKEVFGSGHVPFTPDNVYGILSIFFWTLTVIVSLKYVSLVLRADNNGEGGLIAMLALASTAVQDRPELRKVLLLVGIFGTSLFYGDGVITPAISVLSAVEGLEVISPTFTKAVIPTTLVILFGLFAMQKHGTAGIGKFFGPITIVWFAVLALLGVSQIVTHPEILFALSPHYALMFMWENPGITFIILGAVVLCVTGAEALYADLGHFGKKPIRLAWFSVVMPSLVLNYFGQGALLLSNPAAVKNPFYLMAPDWALIPLVVLATLATVIASQALITGAFSVTKQAIQMGYLPRLRILHTSVRDTGQIYMPFVNWGLFVTIVLAVVMFRSSSNLAAAYGIAVCTDMLITTILTFYVIRYGWKYPLALCIAATSVFFLVDFAFFASNLMKLFAGGWFPLVIGGAVFTLMITWKQGRQILNEKLRTDAIDLSSFLDAVFVSPPLRVEGTAVFMTAEPGIVPNAMLHNLKHNKVLHDQNLFVTVVNHEVPWIGMDKRLQVESLGHDCWQVNIHYGFKNDLDLPRALQQIKNRGCQLEPMTTSYFLSRDTVIPTIGSGMAAWREKLFAQMHHNASGAADFLNLPNNSVVELGSKIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1606_STRPQ
Sequence: MMNMQNMMRQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFTGDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SPs0261.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SIN1_XENLA
Sequence: MAFLDNPLIILAHIRQSHVTSDDTGMCEMVLIDHDIDLEKLYQSSVPGENSTQMQSNGGETQGYVYSQSVDITSSWDFGIRRRSNTAQKLERLRKERQNQIKCKNVQWKDRNTSHSAEELGSLFERKNFKERDLNHGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVYLSMQTSQDKLLPMTVVTIANAKVHDLIGLICWQYTTESREPKLNDNVDAFCLHIAEDDGEVDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLAAKQSLFVRINAAHGFSLIQVDSTNVTMQEILEKALKRRKGSQRNSGPQYRLEKQSQPNVPVDLDSTLESQNSLEFCLVRENSSRGEEHPEEETQIDIATVQDMLSSHQYKSFKVSMIHRLRFTTDVQLGISGEKVEIDPVTNQKTSTKFWIKQKPISIDSDLLCACDLAEEKSPSHAMFKVTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADYFAQKQRKLTRRTSFSFQKEKKTG
What is the function of this protein?
Essential component of the TORC2 complex, which plays a critical role in akt1 'Ser-473' phosphorylation, and may modulate the phosphorylation of pkca and regulate actin cytoskeleton organization.  May interact with a MAP kinase.  May act on Ras-regulated pathways (By similarity).
What are the official names of this protein?
Target of rapamycin complex 2 subunit MAPKAP1, TORC2 subunit MAPKAP1, Mitogen-activated protein kinase 2-associated protein 1, Stress-activated map kinase-interacting protein 1, SAPK-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the SIN1 family.