PharMolix/UniProtQA huggingface dataset:
Protein: SIR3_HUMAN
Sequence: MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK
What is the function of this protein?
NAD-dependent protein deacetylase (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090, PubMed:19535340).  Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090).  Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5PO (PubMed:16788062, PubMed:18680753, PubMed:24121500, PubMed:24252090, PubMed:19535340).  Contributes to the regulation of the cellular energy metabolism (PubMed:24252090).  Important for regulating tissue-specific ATP levels (PubMed:18794531).  In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301).  Acts as a regulator of ceramide metabolism by mediating deacetylation of ceramide synthases CERS1, CERS2 and CERS6, thereby increasing their activity and promoting mitochondrial ceramide accumulation (By similarity).
What are the official names of this protein?
NAD-dependent protein deacetylase sirtuin-3, mitochondrial, hSIRT3, Regulatory protein SIR2 homolog 3, SIR2-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TPM2_BIOGL
Sequence: MDAIKKKMLAMKMEKENAIDRAEQMEQKVRDVEETKNKLEEEFNNLQKKFSNLQNDFDTANEGLTEAQTKLEASEKHVAELESDTAGLNRRIQLLEEDLERSEERLQSATEKLEEASKAADESERGRKVLESRSLADDERLDGLEAQLKEAKYIAEDAERKYDEAARKLAITEVDLERAEARLEAAEAKIIELEEELKVVGNNMKSLEISEQEASQREDSYEETIRDLTQRLKDAENRATEAERTVSKLQKEVDRLEDELLAEKERYKSISDELDSTFAELAGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin-2, Tropomyosin II, BgTMII, TMII.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: HUTU_HALH5
Sequence: MVKETKRMIQAKKGIELECKGWEQEAVLRMLYNNLDPEVAEKPDELIVYGGIGKAARNWAAFEAIVEQLRTLEKDETLLIQSGKPVGRFKTHEQAPRVLLSNSVLVPKWAHWEHFNELEKQGLMMYGQMTAGSWIYIGSQGILQGTYETFAELARQHFGGSLKGTLTLTAGLGGMGGAQPLAVTMNGGVVIGVDVDRSRIEKRIATKYTDRITESLDQALAWASEAKAKGEPLSIGLVGNAAHLHHEILQRGVEVDVVTDQTSAHDPLNGYIPEGHSLEGAELLRKENPQRYMALAKQSMKKHVEAMLAFQRRGAIVFDYGNNIRQVAKDEGLEEAFAFPGFVPAYIRPLFCEGKGPFRWAALSGDPEDIYRTDRLIKELFPENEALIRWIDIAQEKVTFQGLPARICWLGYGERMKMGLEINRLVRNGELKAPIVIGRDHLDCGSVASPNRETEAMKDGSDAVGDWAILNALINTAAGGSWISVHHGGGVGMGYSLHAGMVVVADGTENAEKRLRRVLTTDPGMGIIRHADAGYELAKQVAREKGVMIPMEDKNEEGV
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
Protein: GPX1_SCHPO
Sequence: MSHFYDLAPKDKDGNPFPFSNLKGKVVLVVNTASKCGFTPQYKGLEALYQKYKDRGFIILGFPCNQFGNQEPGSDEEIAQFCQKNYGVTFPVLAKINVNGDNVDPVYQFLKSQKKQLGLERIKWNFEKFLVNRQGQVIERYSSISKPEHLENDIESVL
What is the function of this protein?
Glutathione peroxidase-like protein that protects cells during oxidative stress.  Has peroxidase activity reducing hydrogen peroxide, alkyl and phospholipid hydroperoxides using preferentially thioredoxin as a reducing power.  May act as a scavenger of H(2)O(2).
What are the official names of this protein?
Glutathione peroxidase-like peroxiredoxin gpx1, Glutathione peroxidase homolog, GPx, Thioredoxin peroxidase gpx1.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: OHRL_STAAB
Sequence: MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDPDSESPQLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
What are the official names of this protein?
Organic hydroperoxide resistance protein-like.
What is the protein family that this protein belongs to?
Belongs to the OsmC/Ohr family.
Protein: RUVA_VIBCH
Sequence: MIGRLRGTLIEKLPPQILIEVGGIGYEVQMPMSCIYELPNIGEEAIIYTHFVVREDAQLLYGFNTVSERALFREVIKANGVGPKMGLAILSGMTANQFVTCVEKEDISTLIKLPGVGKKTAERLVVEMKDRLKGWGAGDLFTPATDAAPVDSTPVIAQNAQEEAMSALLALGYKPPQASKAVSQVAKAGMSSEELIREALKSMV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ISPG_LEPIC
Sequence: MNFRYNQTPFGYQRRKTREVKVGDVKVGGNNPIVIQSMINSDTTDTQGSVKQILELERAGCEIVRLTVPSQADADNLPSIRQELKKAGSKVPLVADIHFTPSVAMKAVEYVEKVRINPGNFADKKKFAVRDYTDLKYNQELERISEVFSPLVLRCKELGVSMRIGTNHGSLSDRIMNRYGDTPQGMVESALEFIRIAESLGYYDIIVSMKASNPQVMVQAYRMLASRFNELKMDYPLHLGVTEAGDGNDGRIKSAIGIGSLLEDGLGDTIRVSLTEDPVLEVPVAKLLADKFNKKISNLNSVKGYSEFRNPFSYNRFYSSEIKIVQFEAGENHPVRVETILPFENSNSFLENVAKLYQYGKSLSIEPESILVDSPLPDQLKEISEAATALSIPVGILLSKNVSLNEKLQKELLSFPKIVFDPFLQFQDGEKMLSFLKERQNAGLFSEIHTSGDKLDSLRGLPDTLSEIGIKNVLFSLDSKEILYDYRKLGSILSRFEFPILLHGSFSNPEEALYNSAIGIGGLLIDGIGDLIRISTSKIKDIEEIFQLSYDLLQGTRLRLTKTEYISCPSCGRTLFDLQETTARIKSRTGHLKGVKIAVMGCIVNGPGEMADADFGYVGAGPGKVHLYRGKEIVLKNVPSEIADEKLVQLIKDNELWQDPSND
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: CHDC_BACAA
Sequence: MSEATTTLDGWYCLHDLRSIDWAAWKTLSSDERGQAVSEFLNVVEKWNDVAAAKKGSHAMYTVVGQKADIMLMILRPTMEELNEIETELNKTTLAEYMVPAYSYVSVVELSNYLPADEDPYQNPQILARLYPELPKANHICFYPMDKRRQGDDNWYMLPMEERKKMMYSHSKIGRQYAGKVRQVISGSVGFDDFEWGVTLFADDVLQFKKLIYEMRFDEVSARYGEFGTFFVGNILPDEKVEKFLHI
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: Y579_YERPP
Sequence: MNLQHHFLIAMPSLQDPQFKRSVIYICEHGEKGAMGLVINKPLEQLTVETILEKLKIKSPSRDPAIRLDNVVLAGGPLAEDRGFILHSPQEGFASSIHISPETMITTSKDVLETLGTSGQPKNLLVALGYASWRQGQLEQELLDNVWLTTEADTHILFNTPIAERWQAAANKLGINIFNIAPQAGHA
What are the official names of this protein?
UPF0301 protein YPDSF_0579.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RNH_HALHL
Sequence: MTEQRGVVEAFTDGACRGNPGPGGWGVLLRYGEHERELYGGEPETTNNRMELTAAIRALEALDRPCRVVLTTDSQYVRRGITEWLEGWKRRGWRTASRKPVLNQDLWQRLDELAAYHQVDWHWVRGHAGHAENERADALANQGIDELVA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_ALKCK
Sequence: MNLNKDIATPARTNAILKKHGFTLKKSLGQNFLIDLNILAKIVEASGFDEQDGIVEIGPGIGALTEQLAKKADKVVAFEIDGRLIPVLEDTLSAYPNVKIIHSDVLKADLPGVLDAEFSKGQAIHVVANLPYYVTTPILMKLLEDRLPFKSITVMIQAEVAERIAAKPGSKEYGALSIAAQYYAEAKPMVVVPASVFVPQPRVDSSVLKLTIREKPLVEVIDERWFFNVFHASFANRRKTILNNLVHNLAGKDAKAAIEQALSEAGIDPKRRGETLSPQEFARLSDALYSTLRKAD
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_ECOBW
Sequence: MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRRS5_ARATH
Sequence: MTGINTHFAVALFCFFSFSLRAMSQASQMLIDCTQFDNVTRTSSYLSNRDTVLSTLRNRSSIGSYSNATAGLSPNTIYGMFLCRGDLNRTSCSDCVNATTLEIYKSCFYRKSALVISNECIVRYSNVSFFTLVEDVPSTARFSTGNSLDSPQFFSQTLLEKLDALILRASLSSSLPVPYFVDDQQHVTQLEGSYDLHAMVQCSPDLDPRNCTVCLRLAVQRLSGCCSHAQFARIFYTKCLITYEISALQPNVTSLGVTKSESLTVYII
What are the official names of this protein?
Putative cysteine-rich repeat secretory protein 5.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PETG_CUSOB
Sequence: MIEPFLLGIILGLIPITLIGLFVTAYLQYRRGDQLDF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: CPSC_STRA3
Sequence: MNKIANTEVEINIFNLLKKLWKKKFLITFVAIAFATAGLFYSLFIVTPQYTSSTRIYVINPNTPNNSITAQDLQAGSFLANDYKEIITSTDVLEKVISSEKLNYPSSQLLQKITVSILKDTRVISISVEDANPKMSQKLANSVREAAVSKIKAVTQVEDITTLEKGNLPKAPSSPNIKKNVLIGFIVGAGLSTIVLVIMGILDDRVNTEEDIEKVLGLTSLGIVSDLNKL
What is the function of this protein?
Required for CpsD phosphorylation.  Involved in the regulation of capsular polysaccharide biosynthesis.  May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide (By similarity).
What are the official names of this protein?
Capsular polysaccharide biosynthesis protein CpsC.
What is the protein family that this protein belongs to?
Belongs to the CpsC/CapA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VF268_IIV6
Sequence: MKQRQARLIGTPSQTRRQQELAEKLEKVKEVLEDEKKRQFNEPLFDLTKLRQALDKAIPQPEDVKGFFAQIIKSPSRYEIIFDEAMGVADIEEQEVIEKLRAKEEDEVYDFANNFVRQRRPLPQFFKTFFDKETEKDIFGDIDDISDDENSFTNQDGEAEDNEIITGIRQKDKPEETKEIKLIEQVNMNEGIGRGKILGNKPVFRSVQKSKPFIAEREELKAREGRKRRIQPIPFGIFKEEKLKTCLQFYKLFPWIKDQVLDVFVAPISSNFDDSFFIRSDFYEYISSPVGFAITDDEVEKFYRPKEKYYKLQCYGINKYYNENEPEIIHVNWNNQEYLFKIGILTENRGFLIQEADILLAEEDFIENWLGKSDKRREELLNSVNIPSDAKAVARNEILRSLLNVIPNADLLYTNRILTNIVEKIVDLSLNTSDFFLRVADLIVFINPNINFVSSVFPKRLAKMQYKPEILPLLTQREKLPEIFDDNRIPEATIEYVNRTIHFQIEKVYEDLVNYTVMYNVIPTRKATRPFQMGGKVKPTGRDDKIIIGLPEWKNACVNVNDVINIPDEDLIFYSDIEDQNSDVYCFPINELLDKFSREDIHNQYTGKDFSDTFVRRFLSVYSKPIQAERVVEVERVEEDNIPEGPLIKLIKAELLRLENNLIEPEYFQEEEIKCLECKKAVPAGEGMLSIFKGKKVAFCNMECFENKKW
What are the official names of this protein?
Uncharacterized protein 268L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 268L family.
Protein: DND1_MOUSE
Sequence: MQSKRECEQWCERVNPENKAALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPSGSEVYIGRLPQDVYEHQLIPLFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHQLRPSCQLLVCRSTEKCELTVDGLPLSLNRRALLLALQPFGPCLQETLLLPSPGSAPSQIALLKFSTHRAAAMAKKALVEGQSRLCGEQVAVEWLKPDLKQHFRQQLAGPSLRFLRPDVSQLTQTREKLGSQGARAALQLLCQRMKLGSPVFLTKCLGTGPAGWHRFWYQVVIPGHPVPFSGLIWVVLASDWQDGHEVAKDAVSAQLLEALSEPRTSLWSPGAEAGTMVKQ
What is the function of this protein?
RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression (By similarity).  Relieves miRNA repression in germline cells (By similarity).  Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs (By similarity).  Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs (By similarity).  Does not bind to miRNAs (By similarity).  Isoform 1 may play a role during primordial germ cell (PGC) survival.  However, does not seem to be essential for PGC migration.
What are the official names of this protein?
Dead end protein homolog 1, RNA-binding motif, single-stranded-interacting protein 4.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Perinuclear germ granules, also called germ plasm or chromatoid body (By similarity). Colocalizes in perinuclear sites with APOBEC3.
Protein: NIFW_RHOCA
Sequence: MTPESPTLAALTKLSSAEEIFAFLGVEPIREVLNSSRLHIMKRFGAYLRETDMTGLTEDGIFERARDALLRAQADFVASTPLKEKVFKVFETEAAKRKARFVGLETLKVIKS
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: RLMH_CERSK
Sequence: MKLQLCAVGRLRSGPERDLVEDYLARFERTGRPLGLPAVQLLELEDRKGGGMEAEADLIAKAVAPGAALVVLDERGRTLSSPEFADHLAHWRDSGRDVALAIGGADGLAPRLRDRADLAISLGRMVWPHMLVRVMLAEQLYRAATILAGSPYHRV
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_OSPRO
Sequence: MTNLRKSHPLIKIVNHSFIDLPAPSNISAWWNFGSLLGACLIIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYVGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDALGLMLMLFILLMLALFSPDMLGDPDNFSPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIIPLLHTSKQRSLMFRPISQTLFWILTANLITLTWIGGQPVEQPFIIIGQLASISYFLLIIILMPLAGLFENYMLEPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FIU_ECO57
Sequence: MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTDYGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSIAFGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTATLNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTASIGHDVSTGVEFTRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATACGGSGRGAITCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
What is the function of this protein?
Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate.  It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.  Can also transport catechol-substituted cephalosporins.  Receptor for microcins M, H47 and E492 (By similarity).
What are the official names of this protein?
Catecholate siderophore receptor Fiu, Ferric iron uptake protein, TonB-dependent receptor Fiu.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PIMG_MYCS2
Sequence: MLEMSKRQSPRGAGLAPTIAWRVFQLLTLAGVLWVGWRLLGRVPYRIDIDVYRMGGRAWLDGRPLYADGAIFHTQGGLDLPFTYPPLAAIAFAPFAWLSLPLASSAITATTLVLLIVATTIVLTRLDVWPHTTVTSEPAWMRRAWLAAAMVAPAVIYLEPIRSNFEFGQINVVLMTLVIADCVPRRTPWPRGLLLGLAIALKLTPAVFLLYFLLRRDIHTLLRTAATAVVASLAGFALAWSDSVEYWTETVRNTDRIGTATLNTNQNIAGALARLGLGESPRFILWVLACFAVLALTVWAARRALRGDTADQTTEAPVLALVCVALFGLVVSPVSWSHHWVWMLPVLVVTAVLAYRRRSVWFTALTAAGLALTVWTPITLLPEHRETTASLWRQLAGGSYVWWAFAVIVVIGLVSSSRTHTGDAHETDEPLVPLARGEAG
What is the function of this protein?
Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature Lipoarabinomannan (LAM).
What are the official names of this protein?
Polyprenol-phosphate-mannose-dependent alpha-(1-2)-phosphatidylinositol mannoside mannosyltransferase, Alpha-D-mannose-alpha-(1-2)-mannosyltransferase, Alpha-mannosyltransferase, Alpha-ManT, PPM-dependent mannosyltransferase, Polyprenol-phosphate-mannose alpha-mannosyltransferase, PPM alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 87 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TBPL1_HUMAN
Sequence: MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL
What is the function of this protein?
Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes.  Seems to also mediate the transcription of NF1.  Does not bind the TATA box.
What are the official names of this protein?
TATA box-binding protein-like 1, TBP-like 1, 21 kDa TBP-like protein, Second TBP of unique DNA protein, STUD, TATA box-binding protein-related factor 2, TBP-related factor 2, TBP-like factor, TBP-related protein.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NUOA_BURO1
Sequence: MNLAAYYPVLLFLLVGTGLGIALVSIGKLLGPNKPDVEKNAPYECGFEAFEDARMKFDVRYYLVAILFIIFDLETAFLFPWGVALRDIGWPGFIAMMIFLLEFLLGFAYIWKKGGLDWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
Protein: NADD_CERS5
Sequence: MVVGLLGGSFDPPHAGHVHISLEALKRFRLDRVWWLVSPGNPLKPRPPAPLPARLAEARRLMRHPRVVVTDIEARLGTRFTAETLAALRARYPGVRFVWLMGADNLAQFHRWDRWQGIMRTVPVGVLARPGAGLRSRTSPAARIYARARVGAADLAAARPPAWCFLNLPMVDLSSTAIRATGRWR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: G6PI_PEDPA
Sequence: MAHISFDSSNVADFVHENELAEIQPLVTAADQILRDGSGAGSDFRGWIDLPSNYDKDEFARIKKAADKIRNDSEVFVAIGIGGSYLGARAAIDFLNNTFYNLLTKEQRNGAPQVIFAGNSISSTYLADVLNLIGDRDFSINVISKSGTTTEPAIAFRVLKEKLIKKYGEEEAKKRIYATTDRAKGALKTEADAENYEEFVVPDDIGGRFSVLSAVGLLPIAVAGGDIDQLMKGAEDASNEYKDADVTKNEAYKYAALRNILYRKGYTTELLENYEPTLQYFGEWWKQLMGESEGKDQKGIYPSSANFSTDLHSLGQYIQEGRRNLMETVINVEKPNHDIDIPKADQDLDGLRYLEGRTMDEVNKKAYQGVTLAHNDGGVPVMTVNIPDQTAYTLGYMIYFFEAAVAVSGYLNGINPFNQPGVEAYKSNMFALLGKPGYEDKTAELNARL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.