PharMolix/UniProtQA huggingface dataset:
Protein: PRI1_MOUSE
Sequence: MEPFDPAELPELLKLYYRRLFPYAQYYRWLNYGGVTKNYFQHREFSFTLKDDIYIRYQSFNNQSELEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICSKCWTLMTMAMRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLNEKVHPFVRKSINIIKKYFEEYALVGQDILENKENWDKILALVPETIHDELQRGFQKFHSSPQRWEHLRKVANSSQNMKNDKCGPWLEWEVMLQYCFPRLDVNVSKGVNHLLKSPFSVHPKTGRISVPIDFHKVDQFDPFTVPTISAICRELDMVSTHEKEKEENEADSKHRVRGYKKTSLAPYVKVFEQFLENLDKSRKGELLKKSDLQKDF
What is the function of this protein?
Catalytic subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis (PubMed:8253737, PubMed:8026492).  During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, an accessory subunit POLA2 and two primase subunits, the catalytic subunit PRIM1 and the regulatory subunit PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity).  The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.  These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively (By similarity).  In the primase complex, both subunits are necessary for the initial di-nucleotide formation, but the extension of the primer depends only on the catalytic subunit (PubMed:8253737).  Can add both ribo- and deoxynucleotides during elongation of the primers (PubMed:8253737).  Synthesizes 9-mer RNA primers (also known as the 'unit length' RNA primers) (By similarity).  Incorporates only ribonucleotides in the presence of ribo- and deoxy-nucleotide triphosphates (rNTPs, dNTPs).  Requires template thymine or cytidine to start the RNA primer synthesis, with an adenine or guanine at its 5'-end (By similarity).  Binds single stranded DNA (PubMed:8253737).
What are the official names of this protein?
DNA primase small subunit, DNA primase 49 kDa subunit, p49.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: AMPL2_SOLLC
Sequence: MNGVLCSSSSSFHSYPSIFTKFQSSPIWSFSISVTPLCSRRAKRMAHSIARDTLGLTHTNQSDAPKISFAAKEIDLVEWKGDILTVGATEKDLARDGNSKFQNPLLQKLDSKLSGLLSEASSEEDFSGKAGQSTILRLPGLGSKRIALVGLGSPTSSTAAYRCLGEAAAAAAKSAQASNIAIALASTDGLSAELKLSSASAITTGAVLGTFEDNRFKSESKKPTLKSLDILGLGTGPEIEKKIKYAADVCAGVILGRELVNAPANVLTPAVLAEEAKKIASTYSDVFSANILDVEQCKELKMGSYLRVAAASANPAHFIHLCYKPSSGEIKKKIALVGKGLTFDSGGYNIKTGPGCSIELMKFDMGGAAAVLGAAKALGQIKPAGVEVHFIVAACENMISGTGMRPGDIITASNGKTIEVNNTDAEGRLTLSVGISCNQGVEKIVDLATLTGACVVALGPSIAGIFTPSDDLAKEVVAASEVSGEKLWRLPMEDSYWDSMKSGVADMVNTGGRPGGAITAALFLKQFVNEKVQWMHIDLAGPVWSDKKKNATGFGVSTLVEWVLKNSTN
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.
What are the official names of this protein?
Leucine aminopeptidase 2, chloroplastic, Leucyl aminopeptidase 2, LAP 2, Proline aminopeptidase 2, Prolyl aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL22_THET2
Sequence: MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHGK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CPD1_CANAL
Sequence: MGVALWLCPKRNTPTYDKLITVMSSLNTLFPGSPPKFEPHITITTNISLDLADQSKTKDDVDRILSASAVAMNSLPKNHESLVKLGNVNSQRKFFKKLYFEVEKDPNLVSFARIIRELFVIVPQDIEKENIKQNPQLYTKDNNGNTIRRKPSKKKSKTTEVKEFDTSFIRQAAAYKAAEWSVQEFDPHISLVYSDLWPLHSALWRNINTRISDIDWDIEWEFGVLKLVLCEGDVNDWVVLGSVDIH
What is the function of this protein?
Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.
What are the official names of this protein?
2',3'-cyclic-nucleotide 3'-phosphodiesterase, CPDase.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. CPD1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: OTC_COCIM
Sequence: MAKNQWRPYTNGSHAPSTPRHLLSIADLTPTEFATLVRNASSYKKTIKSDSMPERLTGALSGKTVAMMFSKRSTRTRVSTEGAVVKMGGHPMFLGKDDIQLGVNESLYDTSVVISSMVSCIVARVGPHSDIANLAKHSSVPVINALCDTFHPLQAIADFLTIHESFASQSATHGTHPSSLGLEGLKIAWVGDANNVLFDLAIAATKMGVNVAVATPRGYEIPSHIVELIQKAREGVQSPGNLTQTTVPEVAVKDADVIVTDTWISMGQETEKIKRLEAFKDFKVTSELAKRGGAKENWKFMHCLPRHPEEVSDEVFYSERSLVFPEAENRLWAAISALEAFVVNKGKIA
What are the official names of this protein?
Ornithine carbamoyltransferase, mitochondrial, Ornithine transcarbamylase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SIAP_VIBCH
Sequence: MKTINKITIAILTLSAAASVNAATTLKMGMQASVGSVEYNSAKMLADTLEEMSQGEIKLALYPSAQLGDDRAMLQQLTLGDLDITYAEFGRMGLWIPRAEAVMLPYVAKDFDHLRRMFESDFGQGVRDEMLQKFNWRALDTWYNGTRETTSNRPLNSIEDFKGLKLRVPNAKQNLNYAKLSGASPTPMSFSEVYLALQTNAVDGQENPLPTIKTMKFYEVQKNLAMTHHIVNDQMVIISESTWQKLSDTDKDIIQKAVQKVGDAHTQTVKTQEAELVSFFKSEGINVTYPDLEPFREAMQPLYKEFDSNIGQPIVSKLAAM
What is the function of this protein?
Part of the tripartite ATP-independent periplasmic (TRAP) transport system SiaPQM that catalyzes unidirectional Na(+)-dependent sialic acid uptake.  Binds the common sialic acid N-acetylneuraminic acid (Neu5Ac) with a high affinity.
What are the official names of this protein?
Sialic acid-binding periplasmic protein SiaP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 7 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYFA_STRMU
Sequence: MDLQAQLEELRKSTQATLKEMSGNHSKELQDLRVKVLGKKGSLTELLKGLKDLPNELRPVVGKQVNEVRDVLTKAFEEQAKIVEAAKIQAQLESETLDVTLPGRQIHLGNRHVLSQISEEIEDIFLGMGFQVVDGYEVEQDYYNFERMNLPKDHPARDMQDTFYISEDILLRTHTSPVQARTLDKHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQIEGLVVGKNISMGDLKGTLEMISKKMFGEDRKIRLRPSYFPFTEPSVEVDVSCFKCGGKGCNVCKKTGWIEILGAGMVHPSVLEMSGVNSEEYSGFAFGLGQERMAMLRYGINDIRGFYQGDSRFTEQFN
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASIC3_MOUSE
Sequence: MKPPSGLEEAQRRQASDIRVFANSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVRYYGEFHHKTTLDERESHQLTFPAVTLCNINPLRRSRLTPNDLHWAGTALLGLDPAEHAAYLRALGQPPAPPGFMPSPTFDMAQLYARAGHSLEDMLLDCRYRGQPCGPENFTVIFTRMGQCYTFNSGAQGAELLTTPKGGAGNGLEIMLDVQQEEYLPIWKDMEETPFEVGIRVQIHGQEEPPAIDQLGFGAAPGHQTFVSCQQQQLSFLPPPWGDCNTASVDPDFDPEPSDPLGSPSSSPPYSLIGCRLACESRYVARKCGCRMMHMPGNSPVCSPQQYKDCASPALDAMLRKDTCVCPNPCATTRYAKELSMVRIPSRASARYLARKYNRSETYITENVLVLDIFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLLTILEILDYLCEVFQDRVLGYFWNRRSSQRRSGNTLLQEELNGHRTHVPHLSLGPRPPTAPSAVTKTLAASHRTCYLVTRL
What is the function of this protein?
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride.  Generates a biphasic current with a fast inactivating and a slow sustained phase.  In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue.  May be involved in hyperalgesia.  May play a role in mechanoreception.  Heteromeric channel assembly seems to modulate channel properties.
What are the official names of this protein?
Acid-sensing ion channel 3, ASIC3, Amiloride-sensitive cation channel 3, Dorsal root ASIC, DRASIC.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Cell surface expression may be stabilized by interaction with LIN7B and cytoplasmic retention by interaction with DLG4 (By similarity). In part cytoplasmic in cochlea cells.
Protein: UPP_SALA4
Sequence: MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RS11_MYCCT
Sequence: MANPKPQAKKKIKKNIPKGIAHIHSTFNNTIVTVSDEKGNVLSWSSAGAIGFKGSKKSTPYAAQLISEAAAKGAMDNGVKTVSVEVKGPGPGRDAAIRALQMAGLEITSIKDTTPIPHNGVRPRKRPRG
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: YAE1_SCLS1
Sequence: MFRDHEFPLSSGAFSILTSESAVLNDDFDDVFGSEPGSPAFDVRDGHDGDTFGGGNTEISDIPRLKEKHETEGYRDGVTKGKAESVQKGFDEGYGLGAVLGLRIGKVIGILEGIFGAVSVSAAKSEDTKWTDERSRLEELFKSAKEELKTEKVFAREWWGEDGIWKFEVPGEKEGKDVVFPDVAAAHPLLKKWEGLVEEEIQRWSLDLEFMEGNEEEAVPAKQQIKADAVEQKMGTVKTDLNW
What is the function of this protein?
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery.  May be required for biogenesis of the large ribosomal subunit and initiation of translation.
What are the official names of this protein?
Protein yae1.
What is the protein family that this protein belongs to?
Belongs to the YAE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: OLA1_SCHPO
Sequence: MPPKKQQEVVKVQWGRPGNNLKTGIVGMPNVGKSTFFRAITKSVLGNPANYPYATIDPEEAKVAVPDERFDWLCEAYKPKSRVPAFLTVFDIAGLTKGASTGVGLGNAFLSHVRAVDAIYQVVRAFDDAEIIHVEGDVDPIRDLSIIVDELLIKDAEFVEKHLEGLRKITSRGANTLEMKAKKEEQAIIEKVYQYLTETKQPIRKGDWSNREVEIINSLYLLTAKPVIYLVNMSERDFLRQKNKYLPKIKKWIDENSPGDTLIPMSVAFEERLTNFTEEEAIEECKKLNTKSMLPKIIVTGYNALNLINYFTCGEDEVRSWTIRKGTKAPQAAGVIHTDFEKAFVVGEIMHYQDLFDYKTENACRAAGKYLTKGKEYVMESGDIAHWKAGKR
What is the function of this protein?
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency.  Has lower affinity for GTP (By similarity).  Negatively regulates the G2/M transition in the cell cycle.
What are the official names of this protein?
Obg-like ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SEPF_STRA5
Sequence: MALKDRFDKIISYFDTDDVSENEVHEVQERTSVQRDSRAATAQEASQRSHMTNSAEEEMIGSRPRTYTYDPNRQERQRVQRDNAYQQATPRVQNKDSVRQQREQVTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDAQARRCLDYIDGASRVLYGSLQKVGSSMFLLTPANVMVDIEEMNIPKTGQETSFDFDMKRR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RAY1_ARATH
Sequence: MMSRIEAYQSDIAVLMDPETVLLPDFISALSYAHELGRDWLLVSSSVEIPRFPFHWDETRHFWRQDNGKRVRFRELQKMISLRSLQSNSSASKMIMAWNNIDMPLHCGVLPPFLYQRGTHNQWIINEAMSCKRRFVFDATSTISSFFLGNAENIYNRSDNVSEPKTRNWEYVGNSHLGQLYGSLYSRSYTLPKLLKCNRRYIFVSASERSTDLSIPKGKSLGFRTREKISACITRTKSRSLKLDFVQKDETVPPLKFPFDLESLLPLVADKNRTVVLSVAGYSYKDMLMSWVCRLRRLKVPNFLVCALDDETYQFSILQGLPVFFDPYAPKNISFNDCHFGSKCFQRVTKVKSRTVLKILKLGYNVLLSDVDVYWFRNPLPLLQSFGPSVLAAQSDEYNTTAPINRPRRLNSGFYFARSDSPTIAAMEKVVKHAATSGLSEQPSFYDTLCGEGGAYRLGDDRCVEPETNLTVQFLDRELFPNGAYGDLWLKEDVRAECEKKHCFVLHNNWISGRLKKLERQMMKGLWEYDASMRMCV
What is the function of this protein?
Beta-arabinofuranosyltransferase that transfers specifically an arabinosyl residue from UDP-arabinofuranose to the monosaccharide galactose or beta-methyl-galactoside in vitro.  Catalyzes the addition of a beta-arabinofuranose residue onto a beta-galactosyl residue of an Yariv-precipitable wall polymer in vivo.
What are the official names of this protein?
Beta-arabinofuranosyltransferase RAY1, Protein REDUCED ARABINOSE YARIV 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 77 family.
Protein: NHAK_BACSU
Sequence: MDIFLVVLVLLTIIAISNIVNRFIPFIPVPLIQVALGILAASFPQGLHFELNTELFFVLFIAPLLFNDGKRTPRAELWNLRAPILLLALGLVFATVIVGGYTIHWMIPAIPLAAAFGLAAILSPTDVVAVSALSGRVKMPKGILRLLEGEGLMNDASGLVAFKFAIAAAVTGAFSLAQAAVSFVFISLGGLLCGVVISFLIIRFRLFLRRLGMQDVTMHMLIQILTPFVIYLAAEEIGVSGILAVVAGGITHAVEQDRLESTMIKLQIVSSSTWNIILFILNGLVFVILGTQIPDVISVIFNDTAISNMKVIGYILVITFTLMLLRFLWVLFFWNGKWFFNKDQNIYKPGLRSTLLISISGVRGAVTLAGSFSIPYFLEDGTPFPERNLILFLAAGVILCTLVIATVVLPILTEKEEEDEERNKKLLTARRKLIKTALQTIKEDMNETNKTASLAVIAEYNEKMKNLRFQQYTSSNRIKKHERKVRAQGVKAEQEALMKMLERGDIPEETANVLQERFNELEILYANPFKVGLSKTRLKRLMYWIFFGEHKKPEMSILNEAGLIRATRVKTAKAAIEYLEKHKTDEHKEVFLSVITFYKQLIFRLEHSHHELKSSAHFENQKLEVKLKAVQAIRNEIQTLFEEREISRDISHELRQYINDVEAAMLEGGE
What is the function of this protein?
Transporter involved in the efflux of sodium, potassium, lithium and rubidium.
What are the official names of this protein?
Sodium, potassium, lithium and rubidium/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. Nhak (TC 2.A.36.3.2) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURD2_MICS3
Sequence: MRLSDLRGRTVAVWGAGREGRAAVIAIAAHGPADLVAVDDSANFLALPWEGPLAEAAPLVTGEEGFARLAAAEVVVRSPGVPNTHPWLVELRGRGVTVTQGSALWMADHARRTVGVTGSKGKSTTSSLISHLLTAVDRPNVFGGNIGVPLLDLPDADLYVLELSSYQCADLTDSPRVAVVTALFPEHLDAHGGEREYYRDKLNLLAHGPQTIVVNGADPRLAAELGDRPAVRAGSPDTTHVAPGPDGTPWFHLGDRPLFPRAVLPLVGRHNEGNLCVALAVLAALGVDVVARADALAVAVAGFQGLAHRLTEIADPSGLTFVDDTLATSPYAAMHAIDAYEGRPVTVIVGGADRGLDYAPLREHLAEREITVLGIPDSGQRIVATLAGLPRVRAEVVDDLVAAVRRARELTPADGVVLLSPAAPSYGRFRNFEHRSEVFAEAVRDTAGHPAR
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanine--L-glutamate ligase, UDP-N-acetylmuramoyl-L-alanyl-L-glutamate synthetase, UDP-MurNAc-L-Ala-L-Glu synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAK1_YEAST
Sequence: MDRSDKKVNVEEVNVPSNLQIELEKSGTSSSVSLRSPTKSSATNLAGMAEGARDNASIASSSVDSLNMLLERQRVRQLNHPQHQQHISSSLAKTPTTTSSFCSSGSSKNKVKETNRISLTYDPVSKRKVLNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFELKLFEKIVNDPLKFPTFKEIQSNKVSKVSCEEEYEMAKDLLLKLLEKNPQKRMTIPAIKKHPFVSWDFDHVPENDEKLLSSVLEQKLRFQCNQTDQFEPISISKHELKNAVSGVGKKIKESVLKSIPLKDPSDLSNKNYLHPTETTRGRGDANVIVSEGSVLSNIKELSANDGCLNTDSDTNININDDDHYSGDDNDGHLTKRELERELNKFDDKHEAGNMVNLPINSSFASLDSFYIDNFAMARMGMSSPEAGDSVSSVPNLPSAPSSTRLGRSPVFSGVTNQPSPIRPVLPQQKSSFCATGRYDKSHNSLLRNSSSHLTSYNSGRPSSRTGRMNSRNQNLPKIPNSLSKISTTKLTELRVPKDSEIPSPAKNPNADRLRRFPVKKNTKTPAIKDPPRININSSDKSGSKNSPIKSLYQRMKQSKDNSKTFEVRRGNFFSHFNGDDDDSSSQSSVTSSGSESDSELSSTSSSCTSGTQSRNSSNNNAYSETESLPFEFGVDSEDGSGVLLRDLPNEDQIRPFLDIQPCRRMKVKSSLNLEPPSVSSSSSSSSDEDELILNVGTAGHRRRHNSSKLSELSNSPQKGSNNFMYSNGSVHDSETTITPQNMDDLTLHQALSRSQPISKPGPLVLPKRLDQKKATTETSNLTDIVEFNGNNDHRKDKNFDKVLYSRDLLKDALSSTNAGRRRSIPSNKIRGRKDASITMSTNVGNDEHARNTSCHGDKGQENGAIKQRTHERSRSLTVAELNEEKRRSALP
What is the function of this protein?
Serine/threonine-protein kinase that phosphorylates SNF1, the catalytic subunit of the SNF1 kinase complex.  Acts as an activator of the SNF1 kinase complex and controls its nuclear localization upon glucose and nitrogen depletion.  Also required for SNF1 kinase activation under other stress conditions like alkaline pH or presence of cadmium.
What are the official names of this protein?
SNF1-activating kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP23_YARLI
Sequence: MSDKPTETVSVSESVATPAVAATEPAPSLPVVNPSSLPSGFEWWRQTMAYKTGFMSAEESVQYEQDRLIKERYAECLSCEKNKQWVMAYSPTVRFMKDQIEKIGGDISSNNVFCDHCDDFKAGGFHPKYGILVCQNHVKSRSHLEDTLAHEMVHYYDNTKFKVDWMNLKHHACSEIRASTLSGECRMMNELMKGKLARLTRGHQECAKRRAILSVMANPGCKDEAQATQVVNEVWDSCFNDTRPFDTIYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: PTLCB_STRMU
Sequence: MNTLIAQIEKGKPFFEKISRNIYLRAIRDGFISAMPVILFSSIFLLIAYVPNIFGFTWPKGIENMLMTPYNYTMGIIGFLVAGTTAKSLTDSMNRQLEKTNQINFISTMLASMAGFLIMAADPAKEGGFLSAFMGTKGLLTAFIAAFITVNVYKICVKNNVTIRMPEEVPPNISQVFKDIFPFAFSIIILYAIQLAIKAVIGVNVAQSIGTLLAPLFSAADGYLGITIIFGAYALFWFVGIHGPSIVEPAIAAITYSNVELNAHLIHAGQHADKVITSGTQMFIVTMGGTGATLVVPFMFMWLCKSKRNKAIGRASVVPTFFGVNEPILFGAPIVLNPVFFIPFILAPIVNVWIFKFFVDTLGMNSFFANLPWTTPGPIGIVLGTGFAVLSFVLAALLILVDTVIYYPFVKVYDEQILAEEAEGKSSSDALKEKVAANFDTKKADAILEGAESKEEPATHAITEETNVLVLCAGGGTSGLLANALNKAAEEYGAPVKAAAGSYGAHREILDQYQLVILAPQVASNYEDMKAETDKLGIKLAKTEGAQYIGLTRDGKGALAFVEEQFKD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II LacEF PTS system is involved in lactose transport.
What are the official names of this protein?
PTS system lactose-specific EIICB component, EIICB-Lac, EII-Lac.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AFN_CALVI
Sequence: HGVSGHGQHGVHG
What is the function of this protein?
Antimicrobial peptide presumably with antiparasitic, antiviral and/or antitumoral activities.
What are the official names of this protein?
Alloferon-1.
What are the subcellular locations of this protein?
Secreted.
Protein: COXX_HALSA
Sequence: MGVYSLLVLGATTSLTGAASACQTWPSCNGQWFALQSLDLVVVWGHRTAAALTGLAVVGAAVLAWRTGASRRVRTAVTLALALYPVQVVIGAYTAMSAGAAPFTGVHLTLGVGIFASLVVALAWTLDAQTGDLPSAEWEGEPRHTDDGDPTQPGIVRAYVQLMKPRLMWLLCLVAGAGMALASSQLGAGQQLSAATVVLTLGGGVLSIGASGTFNHVLEREQDEKMARTDDRPVVTDRIPPRNALAFGVVLGVASLAAFAAVNLLTAVLGLTAIAFYSIVYTLVLKPNTRQSTVIGGAAGALPALIGWVAVTGAVGVGGVVLAGVIFLWTPAHFYNLALAYKDDYERGGFPLMPVVEGEAKTRRHIVYYIGATLASAVVLAELTGLGPLYAATTVLLGAVFLYFAIRLHRERDRRAAMRSFHASNAYLGCLLVAVVLDTMVV
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRH4_NEUCR
Sequence: MWKTARDSVCLICRSAATTTTSTSARASLEPWAGQRTFSTRREQRPSRMVLSDRVARPPPVRGPGEGNKKPRNKPDGPWAGMNRRVANIDPRKAPKPKPVEEDSRRDKRDKNTKGQKALKMQRALATISYGQRTSIKERMQEIQAFDQFDLLPVVKEAIAQEALKGMTEIKPTPVQRLAIPALLGQPMGRKPRRPKSDNGREEFLLAAETGSGKTLAYLVPAVNAIKKGDADDELVASYNERLAAEKERRGGAPVSEWIEKFEPHPNTARPRVVVLVPTAELVDQVTSVAKKLAHYTKFKVRPLSASISPLRNQRNLYSPIGVDMIVSTPHLLATIAKSDPNVLSRVSHLVIDEADSLLDRSFSGDTTSIVDRAMPSLKQLILCSATIPRRLDTYMEEQFPYINRITTPNLHAIPRRVQLGVIDVSKDPYRNNKMLACADAIWSIGKEAAKHEGPKSEIDVKRIMVFVNERETTQQVADYLVSKGIDAIALHRDTEEHRKSEMLASFTSNEPMKISRPADDDVAAAAAEGGKAGGAVSSSPTRRHLPNTKVIVATDLASRGIDTLAVRYVVLYDVPHTTIDFIHRLGRAGRMNRRGRGIVLVGKDDRRDVVAEVKESMFMGQALV
What is the function of this protein?
ATP-binding RNA helicase involved in mitochondrial RNA metabolism.  Required for maintenance of mitochondrial DNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase mrh4, mitochondrial, DEAD box RNA helicase 15.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. MRH4 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MCA2_TRYB2
Sequence: MCSLITQLCDAGQLADYVGLGWLNAVSSQPYLVQALGLQPPPRRVDVDAAFRDAKGLHGHQPWVATPLPGQTVRALFIGINYYGTSAALSGCCNDVKQMLATLQKKGLPINEAVILVDEDNFPGRTDQPTRDNIVRYMAWLVKDAKPGDVLFFHYSGHGTQCKSRGDSDEKYDQCIAPVDFQKSGCIVDDDIHKLLFSRLPEKVRLTAVFDCCHSGSIMDLPFTYVCSGGEQASGTPHMKRIREGNDVLGDVMMISGCADEQTSADVKNTATFGTGSTGAGGAATQCITCMLMNNQSLSYGKLLIETRDMLKRKGFKQVPQLSASKAIDLDQTFSLTEMFSVDRSIQ
What is the function of this protein?
Cysteine protease that cleaves specifically after arginine or lysine residues.
What are the official names of this protein?
Metacaspase-2, TbMCA2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
What are the subcellular locations of this protein?
Recycling endosome.
Protein: ATPE_POPAL
Sequence: MILSLCVLTPNRIVWDSEVKEIILSTNSGQIGILPNHAPIATAVDIGILRIRLNDQWLTMALMGGFARIGNNEVTVLVNDAEKGSDIDPQEAQQTLEIAEANLRKAEGKRQIIEANLALRRARARVEAINVIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SMG_YERPE
Sequence: MFDVLIYLFETYMHNEPEMLVDQDKITDDLADAGFYREDINNALNWLEVLADLQEGQKAPYLYTADPQALRIYTVEECRRLGAACRGFILFLEQIQVLQFDTREMVIDRIMALDSPEIDLEDLKWVVLMVLFNIPGYENAYKQMEELLFEVNDGYLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: FER_BUTME
Sequence: AYKITDECIACGSCADQCPVEAISEGSIYEIDEALCTDCGACADQCPVEAIVPED
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.