PharMolix/UniProtQA huggingface dataset:
Protein: PDXB_ALCBS
Sequence: MHIIADANMPGLEPFEAFATVERVDGRSLTREQLGDADVLLVRSVTRVDRALLAGSQVKFVGSATIGTDHVDLAYLSEAGIQFAHAPGCNARAVAEYVLQAVLLLCARQGREVQGARVAVVGLGNVGRRVADWLSALGMEVRGCDPLLDAQGYAGPVALAPLDDLLDADIITLHVPLTQSGEHATGHLLDASRLSRLGPGQMLINTCRGPVIDNLALSQQLASGTGPMTVLDVWETEPQVPATLYQQVVMGSPHIAGYSLEGKLKGTSMLYDAVCQWSGQGIASGTAMADAPPLNPAVNSEADLLALLQVAYRLEDDHRRLGESLHDTDPSAAFDRLRKHYPVRHELHYWQYDGSVDDTWRAIISRLFEPD
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APO1B_THEGE
Sequence: MRLFLSLPVLVVVLSMVLEGPAPAQGAPDVSSALDKLKEFGNTLEDKAWEVINRIKQSEFPAKTRDWFSETFRKVKEKLKINS
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification.  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, basic form, Apo-CIB, ApoC-IB, Apolipoprotein C1B.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SSTT_SHELP
Sequence: MNQNRSLFAKLADGSLVLQIILGIIAGVALASFSPSSAESVAFLGDLFVGALKAIAPILVFILVAASIANQKKNTKTNMRPIIVLYLFGTFAAAITAVTMSFLFPTSLVLVSGAQGATPPEGIGEVLNTLLFKVVDNPVNALMTGNYIGILAWGVGLGIALHHASENTKTVFADVSHGVSQMVRFVIRLAPIGIFGLVANTFAATGFEAIAGYAQLLAVLLGSMLIIALIINPLIVWFKIRRNPYPLVFTCLRESGVTAFFTRSSAANIPVNMALCEKLDLHEDTFSVSIPLGATINMAGAAITITVLTLAAVHTEGIQVDILTAILLSVVAAVSACGASGVAGGSLLLIPLACSLFGISNDVAMQVVAVGFIIGVIQDSAETALNSSTDVLFTAAACEAAERQAEI
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KDPC_METPB
Sequence: MLTHLRPALVLLTALTAITGLAYPLAMTGLAGAIFPARAAGSLIERDGRIVGSALIGQSFSQAHYFHGRPSVTTATDPADAGKTVPAPYNAANSMGSNLGPTSAVLAERVKGDLAALSAENPGAPVPVDLVTTSGSGLDPDIAPEAALFQVPRVARARGMPEDRLRALVTAQVEGRTFGVLGERRVNVLALNLAVDELARR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CLPS_PSESM
Sequence: MHAFSKIRLTFNQDGPQSHEDDSAGIAVQDAKPTLQAPPMYKVVLFNDDYTPMDFVVEVLEVFFNLNRELATKVMLAVHTEGRAVCGLFTRDIAETKAAQVNQYARESQHPLLCEIEKDG
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RL2_ACIAD
Sequence: MPIQKCKPTSPGRRFVEKVVHSHLHKGKPFAALVEAKKRTGGRNNNGHITTRHVGGGHKQHYRLVDFKRNKDGIPAVVERIEYDPNRTAHIALLKYADGERRYIIAPKGLRAGDKVQSGNDAPIRPGNCLPLRNMPIGSTLHNVELKIGKGAQLARSAGTSVQLLGRDGSYAIVRLRSGEMRKIHVECRAVIGEVSNQENNLRSLGKAGASRWRGVRPTVRGMAMNPVDHPHGGGEGRNKGIQPVSPWGQKAKGYKTRTNKRTTKMIIRDRRVK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ATPG_BACVZ
Sequence: MASLRDIKSRITSTKKTSQITKAMQMVSAAKLNRAETNAKSFAPYMDKIQEVVFNVGKGAKNAKHPMLVSREVKKTAYLVITSDRGLAGAFNSSVLRNAYRTIQERHQSKDEYTVIAIGRVGRDFFKKREMPILSELVGLGDEVTFAQIKDLTRQTVQMFIDGAFDELHLVYNHFVSAISQEVTEKKVLPLTDFGTSGGKRTASYEFEPDEEEVLEVLLPQYAESLIYGALLDSKASEHAARMTAMKNATDNAKELIDSLSLSYNRARQAAITQEITEIVGGAAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RAB41_HUMAN
Sequence: MSAFGHDEAWMEAGGFGLEAAERTEYQSLCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTRTSPPPKEGTVEIELESFEESGNRSYC
What is the function of this protein?
Required for normal Golgi ribbon organization and ER-to-Golgi trafficking.
What are the official names of this protein?
Ras-related protein Rab-41.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm. Note=punctate localization concentrated in ruffled regions at the cell periphery.
Protein: RL39_ICTPU
Sequence: MASHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
What are the official names of this protein?
60S ribosomal protein L39.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: MTND_PEDHC
Sequence: MVQAWYMDNSTEDQRLQHHRTPPKFIDMNELFKRTGVEYFKVNEKDPVNDDLLIKLKKERCYSYEDEITCSEQCLPNYHEKLKNFFTEHLHTDEEIRLVLEGSGYFDVRDPSDEWIRIFVQPGDMIIIPSGIYHRFTLDDKNYIKAKRYFIGEPVWTPHNRPADNMPCRQEYLGKLLKGF
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIMP_GLAP5
Sequence: MATLEQKLQELVADPIDAMGFELVGVECQRAGRFLTVRLYIDKEGGVTVDDCSDVSRQVSAIFDVEDPIADKYNLEVSSPGLDRPLFTLAHYQRFVGREIVVHLRIPMLDRRKWQGELVSVEGDLITLKVDGNLQAFAFGNIQKANLIPVFNF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_ACTP2
Sequence: MTTTNRLRIALQKKGRLSKDCNELLKQCGVKINWNEQRLIAYAENMPIEILRVRDDDIPGLVFEGVVDLGIIGENVLEEEELGRLARGEKIEYKKLRTLDFGGCRLSLAIDRDRTYNGVQDFVNSRIATSYPNLLKRYMNEKGVAFKSTLLNGSVEVAPSAGLADAICDLVSSGATLEANGLKEVEVIYQSKACLIQRAEPLSTEKQALVDRLLTRIQGVQQAAESKYIMLHAPKDKLKEITALLPGVENPTILPLANDSARVAMHVVSQENLFWETMEQLKEMGASSVLVLPIEKMLA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMP7_STAAE
Sequence: MKFKSLITTTLALGVLASTGANFNNNEASAAAKPLDKSSSSLHHGYSKVHVPYAITVNGTSQNILSSLTFNKNQNISYKDLEDRVKSVLKSDRGISDIDLRLSKQAKYTVYFKNGTKKVIDLKAGIYTADLINTSEIKAININVDTKKQVEDKKKDKANYQVPYTITVNGTSQNILSNLTFNKNQNISYKDLEDKVKSVLESNRGITDVDLRLSKQAKYTVNFKNGTKKVIDLKSGIYTANLINSSDIKSININVDTKKHIENKAKRNYQVPYSINLNGTSTNILSNLSFSNKPWTNYKNLTSQIKSVLKHDRGISEQDLKYAKKAYYTVYFKNGGKRILQLNSKNYTANLVHAKDVKRIEITVKTGTKAKADRYVPYTIAVNGTSTPILSDLKFTGDPRVGYKDISKKVKSVLKHDRGIGERELKYAKKATYTVHFKNGTKKVININSNISQLNLLYVQDIKKIDIDVKTGTKAKADSYVPYTIAVNGTSTPILSKLKISNKQLISYKYLNDKVKSVLKSERGISDLDLKFAKQAKYTVYFKNGKKQVVNLKSDIFTPNLFSAKDIKKIDIDVKQYTKSKKNK
What is the function of this protein?
Binds various plasma and ECM-proteins.
What are the official names of this protein?
65 kDa membrane protein, map-ND2C.
What are the subcellular locations of this protein?
Cell membrane.
Protein: GPA1_SOYBN
Sequence: MGLVCSRSRRFREAHAEENAQDAEIERRIELETKAEKHIQKLLLLGAGESGRSTIFKQIKLLFQTGFNEAELKSYIPVVHANVYQTIKVLQDGSKELAQNDFDSSKYVISNENQDIGQKLSEIGGTLVYPRLTKELAQEIETMWEDAAIQETYARGNELQVPDCAHYFMENLERLSDANYVPTKEDFLYARVRTTGVVEIQFSPVGENKRSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCSAISEYDQTLYEDENKNRMMETKELFEWVLRQPCFEKTSFMLFLNKFDIFEKKVLNVPLNVCEWFKHDYQPVSTEKQEIEHAYEFVKKKFEELYFQSTAPDCVDRVFKIYQATAPDQKLVKKTFKLGDETLRRRNPLEAGLL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-1 subunit, GP-alpha-1.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: Y3380_VIBCH
Sequence: MSIWNKPISLEILNATSKNTLIEHLNIIYTEVTENSISATMPVCHFTHQPLGMLHGGASVVLAETLGSVAANFSVGEDAYCVGLDINANHVRAMREGLVTGTAVPLHIGVSTQVWQIEIKDEQGRLVCISRLTVAVKRSRPNQAKPVAEV
What are the official names of this protein?
Putative esterase VC_A0580.
What is the protein family that this protein belongs to?
Belongs to the thioesterase PaaI family.
Protein: COAA_HALH5
Sequence: MATIEACDFFPYTVLSRSQWKSLRKASSLPINEQELEQLVGLNEPITLNEVADIYVPLAELLHVHATAYQRLQQQKRGFFHHGKNRSPFIIGLAGSVAVGKSTTARLLQKLLKAWPEHHHVDLVTTDGFLYPNETLEARGLMDKKGFPESYDLPALIRFLSDVKAGEPYVKAPVYSHLTYNIVEGDYQVVHEPDIVIVEGINVLQVNKRNHHIPNVFVSDFFDFSIYVDAKEEQILQWYIERFKLLQNTAFQDPNSYFHRFRHLSEVEAEQFATSIWKNINGVNLHENILPTKHRADLVLQKGPHHFIDEVKLRNI
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
Protein: COAA_MYCBP
Sequence: MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTAFADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_SPHAL
Sequence: MTATRHFLLAAGGTGGHMLPAYALADELIARGHRVALVSDDRGLKIPGAPAELETHVLPAGRASGGPLGWLKGALAIRKGRRMAIELIDDFDPAVVVGFGGYPSLPSLLAAGATKRPRVIHEQNAVLGRVNRLMAPRVDAVAVAYHHIQRYPAGHELKMHITGNPVRDEIVAIREEGFPPLLEDGIFRLLVVGGSLGATVLSEVVPAAIAMLPRALLDRLQVVQQCREDDLEAVRARYAELGVAAECAPYIKDFPERLRWAHMVIARAGASTVAELACAGRPAIFVPYPHAMDDHQTYNVVDLVEAGGAISFRQSDFIPAEVAKHIQRMAVEPGVLEEAAERAASCGLPDATRDLADLVESFAAPPMMDVIRVGASLPRAASGIAAARREAK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: POLS_CHIKN
Sequence: MEFIPTQTFYNRRYQPRPWTPRPTIQVIRPRPRPQRKAGQLAQLISAVNKLTMRAVPQQKPRKNRKNKKQKQKQQAPRNNMNQKKQPPKKKPAQKKKKPGRRERMCMKIENDCIFEVKHEGKVTGYACLVGDKVMKPAHVKGTIDNADLAKLAFKRSSKYDLECAQIPVHMKSDASKFTHEKPEGYYNWHHGAVQYSGGRFTIPTGAGKPGDSGRPIFDNKGRVVAIVLGGANEGARTALSVVTWNKDIVTKITPEGAEEWSLAIPVMCLLANTTFPCSQPPCAPCCYEKEPEKTLRMLEDNVMSPGYYQLLQASLTCSPRRQRRSIKDNFNVYKATRPYLAHCPDCGEGHSCHSPVALERIRNEATDGTLKIQVSLQIGIKTDDSHDWTKLRYMDNHMPADAERAGLLVRTSAPCTITGTMGHFILARCPKGETLTVGFTDGRKISHSCTHPFHHDPPVIGREKFHSRPQHGKELPCSTYVQSNAATAEEVEVHMPPDTPDRTLMSQQSGNVKITVNSQTVRYKCNCGDSNEGLTTTDKVINNCKVDQCHAAVTNHKKWQYNSPLVPRNVELGDRKGKIHIPFPLANVTCRGPKARNPTVTYGKNQVIMLLYPDHPTLLSYRNMGEEPNYQEEWVTHKKEVRLTVPTEGLEVTWGNNEPYKYWPQLSTNGTAHGHPHEIILYYYELYPTMTVVVVSVASFVLLSMVGVAVGMCMCARRRCITPYELTPGATVPFLLSLICCIRTAKAATYQEAAVYLWNEQQPLFWLQAIIPLAALIVLCNCLRLLPCCCKTLTFLAVMSVGAHTVSAYEHVTVIPNTVGVPYKTLVNRPGYSPMVLEMELLSVTLEPTLSLDYITCEYKTVIPSPYVKCLRYSECKDKSLPDYSCKVFTGVYPFMWGGAYCFCDTENTQLSEAHVEKSESCKTEFASAYRAHTASASGKLRVLYQGNNVTVSAYANGDHAVTVKDAKFIVGPMSSAWTPFDNKIVVYKGDVYNMDYPPFGAGRPGQFGDIQSRTPESEDVYANTQLVLQRPSAGTVHVPYSQAPSGFKYWLKERGASLQHTAPFGCQIATNPVRAMNCAVGNMPISIDIPDAAFTRVVDAPSLTDMSCEVPACTHSSDFGGAAIIKYAASKKGKCAVHSMTNAVTIREAEIEVEGNSQLQISFSTALASAEFRVQVCSTQVHCAAECHPPKDHIVNYPASHTTLGVQDISATAMSWVQKITGGVGLVVAVAALILIVVLCVSFSRH
What is the function of this protein?
Class II viral fusion protein.  Fusion activity is inactive as long as E1 is bound to E2 in mature virion.  After virus attachment to target cell and endocytosis, acidification of the endosome would induce dissociation of E1/E2 heterodimer and concomitant trimerization of the E1 subunits.  This E1 trimer is fusion active, and promotes release of viral nucleocapsid in cytoplasm after endosome and viral membrane fusion.  Efficient fusion requires the presence of cholesterol and sphingolipid in the target membrane.  Fusion is optimal at levels of about 1 molecule of cholesterol per 2 molecules of phospholipids, and is specific for sterols containing a 3-beta-hydroxyl group.
What are the official names of this protein?
Structural polyprotein, p130.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm. Host cell membrane. Host nucleus. Note=Shuttles between the cytoplasm and the nucleus. SUBCELLULAR LOCATION: [Spike glycoprotein E2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [6K protein]: Host cell membrane; Multi-pass membrane protein. Virion membrane; Multi- pass membrane protein. SUBCELLULAR LOCATION: [Spike glycoprotein E1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: RS10_PROMP
Sequence: MTASLTQQKIRIRLKAFDRRMLDLSCDKIIQTADTTAASAIGPIPLPTKRKIYCVLRSPHVDKDSREHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CC198_MOUSE
Sequence: MGLGHSKAHPRVIKVTPLQSQETETPSTGPVFFALNRNLEEESSFTRLQDQNRTREGQLPPLRETWYGRLPAVSRAMYLDIPLKHEETSIIKRHPPRRIQKLEPIDLPQAITSERLLCHQEGRTKSNTKQENEKKIQLPMYTSGKRQYLHKMKMLEMNHKRQEAQMELRKSLLSKAMLDMQKLKDHNGNKIAQSKPRSNGYDILTILPNENINRDPGNPQDEEFLDCHTENDYYVRKIGKMETWLREQEARGQLFWDSSSSDSDELEKDERRPQALVRTKTEKIPLYDDFYDSA
What are the official names of this protein?
Uncharacterized protein CCDC198.
Protein: Y1447_STREM
Sequence: MRKAFYTWLMAQRHSTSNKPAALLADLVFEDTTFPKHTDDFETISRYLEEEASFAFNLGQFDQIWEDYLSH
What are the official names of this protein?
UPF0346 protein Sez_1447.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: MD10A_ARATH
Sequence: MDQTQNTIAGIGEINGSIKTEINAIATVDDSNEKLNQIINSNQKILELLHQLKLTVSSFTPASQLHLLQRLNSLVMELDNMAKLSDKCNIQVPIEVLNLIDDGKNPDEFTKDVLNKNCIAKNQVTKGKSDAFKGLRKHLLEELEQAFPDEVDRYRDIRASYAAEAKRLAQTQSVLPNGDAKVKSEL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 10a.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTRF_METKA
Sequence: MAEEGSELKEVIIGAPAMADTDRADTYVNDVRDSSQFFGRDARLYFGLNVNRFAGLACGMVFAGVLLVPLLLLAF
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit F, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit F.
What is the protein family that this protein belongs to?
Belongs to the MtrF family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YES_DANRE
Sequence: MGCVKSKEDKGPTQKYRPDPTNPTPGSHMGLYGPDPTQMGQSPALKGPTNNYNSRSSGLTPFGGSSSVITPFGGASSSFSTVAVNNPFPGVVTGGVTFFVALYDYEARTSDDLSFSKGDRFQIINNTEGDWWEARSINTGQKGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLLPGNQRGTFLVRESETTKGAYSLSIRDWDEMKGDNVKHYKIRKLDSGGYYITTRAQFDTLQKLVKHYTEHADGLCYRLTTVCPTVKPQTQGLAKDAWEIPRESLRLELKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEYMGKGSLLDFLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMRLCWKKEPDERPTFEYIQSFLEDYFTATEPQYQPGDNL
What is the function of this protein?
Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, differentiation, G2/M progression and cytokinesis (By similarity).  Required for convergent extension cell movements during gastrulation, acting with fyna via rhoa.  May be required for epiboly to occur, possibly through its effects in calcium signaling.  During embryonic development, phosphorylates ptk2. 1/fak.
What are the official names of this protein?
Tyrosine-protein kinase yes, p61-Yes.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol.
Protein: GLAH_ECO81
Sequence: MNALTAVQNNAVDSGQDYSGFTLIPSAQSPRLLELTFTEQTTNRFLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGIDDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELHNDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDLFFRHPLARRPMRFAAPPSKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDTIETSKGTLSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHHYQTHQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: RNH2_DESRM
Sequence: MVLECGVDETGRGSCISGIYASACILDPAHPIEGLRDSKKLSARKREILAEEIKQYALSWCIAQASLEEVEQLNVHHATLLAMKRAIEGLSIRANKVYVDGIHLPEVDIPAEAIVKGDDLIPAISAASILAKVARDGAMLEYHEKYPQYGFNSHKGYLTKAHREALKKYGPSPIHRKTYAPIRELLVGKDNEQIEMFE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRVB2_MACMG
Sequence: AFAGILADADCAAALKACEAADSFNYKAFFAKVGLASKSAEEIKKAFFVIDQDKSGFIEEDELKLFLQNFVAGARALTDAETKAFLKAGDSDGDGAIGVDEFAALVKA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin beta 2.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: SFH5_LODEL
Sequence: MSEVDEGIQNLSIEKADAGATATATATATTAEKHNQALNSTLKTGLDKSVESQTANSAGSSPTSATSSSNNPHYDVKSTIKSTKLNDEQAQKLTKLISSVPDILKQTKNPAYDEIFGYRINSDGLEYVDIPKRNEILLKFLAADNYDLDLATKRLIATFNWRNEFQPLHAAFDEKFHQELNELGVITQFASGNDNLHVITWNLYGNLKSPKKIFQKFGEGADDGQREGLAKSSSNSNSSSSSSSSGNNRGKNLPGSQFLRWRIGLMEKALQLVDFTDSKNHKIAQIHDYNNVSMFRIDPGMKAATKEIIEIFGQNYPELLSTKYFINVPLIMGWVFTFFKTIGVISAETLKKFQVLNHGDLKETLPKQELPESYGGVKSAKGDPKRSLFDLDVSESIKLTKYGQVVLQRLGDEEIAHNNDEVE
What is the function of this protein?
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity.  Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.  Heme-binding protein that may play a role in organic oxidant-induced stress responses.
What are the official names of this protein?
Phosphatidylinositol transfer protein SFH5, PITP SFH5.
What is the protein family that this protein belongs to?
Belongs to the SFH5 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.