PharMolix/UniProtQA huggingface dataset:
Protein: GLND_HYDCU
Sequence: MATTTDKQVSPTSPSFVYNLDHEDRNTSLKSGRAVLTDFNEQQFVKFDKGCSIETLLKERTSFIDQLLKKIWEHFFSKDECEQLTLVAVGGYGRGELQPYSDIDLLILGENFIELQPKIVEFITYLWDIGFEVGHAVRNLEDCIEAGREDVTTATNLLEARWLAGNYEQFLSLQNLFNLKSFWPSHEFFQAKLEEQEKRHKRYNDTLYQLEPNIKESPGGLRDIQTILWVAKRHFGASSLQELMQHNFISLQEYKEIQAAYLYLNRIRFALHRLKKRHEDRLLFDHQQQLAELLNHDDRPEHNDSIKAVEAFMKPYYQNAHIVARLNEILLQHFKEEIYHFAEDKIEPINPRFRIINNYLDVVKENLFAKNPTALLEIFIIIENYQHLIQGIRSRTIRLIRNHLHLIDDQFRSDPINKALFIEIFRQPKGVNAAVKRMYAYGILGAYLPSFKKITGLMQFNIFHAYTVDEHTILVIRNLRRFFIKQHAYEFPTAHQIATQLCKPEILLLAGLFHDIAKGRNGAHEKLGAVDAKAFSQKHNLNKNDTDLLSWLVLRHLDFSYVAQKKDLSDPEIIQQFAEKVGTQQRLDYLYLLTLADVRSTSDEVWNDWKNQLFLQLYHNTTQALDSSSSQPRDRVKQAIFNKEKASELLKKRGLIPMHFQGFWQAFEQTDFFNRQSAAEIARITRVLFEEDHEAINIHLQPTTSRGATELIIYMHDRDYLFAQFTQIIDKLDLNIVEAKIYSGEDDMTLVIIYLLNRESTSITDPMILTEIEETLKHQLFLKDDTMPPTQPEPRRIRVFEMPTHIQFQEINEELTELSISTKDIPGLLAKIGQAFKSCKIRVHDAKINTVGEKAEDTFMISSTTNESIHTRHSQEELKQALLNNIEQ
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: SCX5B_CENLI
Sequence: MNSLLMITACLAEIGTVWAKEGYLVNKSTGCKYGCFWLGKNENCDKECKAKNQGGSYGYCYSFACWCEGLPDSTPTYPLPNKSCSKK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Cll5b.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KIWEL_ACTCC
Sequence: MAQLSLLVLSLFLTLISLPPPGASISSCNGPCRDLNDCDGQLICIEGKCNDDPEVGTHICRGTTPSPQPGGCKPSGTLTCRGKSHPTYDCSPPVTSSTPAKLTNNDFSEGGDGGGPSECDESYHSNNERIVALSTGWYNGGSRCGKMIRITASNGKSVSAKVVDKCDSRHGCDKEHAGQPPCRNNIVDGSNAVWSALGLDKNVGVVDITWSMA
What is the function of this protein?
Kissper is an anion-selective pore-forming peptide.
What are the official names of this protein?
Kiwellin.
What is the protein family that this protein belongs to?
Belongs to the kiwellin family.
What are the subcellular locations of this protein?
Secreted.
Protein: A7637_ARTBC
Sequence: MKASLITAFVLPLLALASPYLPTDPPANIEVTARHPGRENVDKLPMQAAGRAFWLGGSPATYCPEIVGDNCPPGNATVILGLNSMSVLVPGGQQMYVEPSGKLGFTQAHSAAIPPGSYVGGFAYKPLNKKSGSFYFGGWGATALMACPVPDSKYYQVFANIKNAMVPGGDVKKCVEFVGVAKEYKGTTPAAWQYT
What are the official names of this protein?
Uncharacterized secreted protein ARB_07637.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRD_TRYCC
Sequence: MMCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.  Molecular oxygen can replace fumarate in vitro.
What are the official names of this protein?
Dihydroorotate dehydrogenase (fumarate), DHOD, DHODase, DHOdehase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VME1_BCHK5
Sequence: MASSNVTLSNDEVLRLVKDWNFTWSVVFLLITIVLQYGYPSRSMFVYVIKMFVLWLLWPASMALSIFCAVYPIDLASQIISGILAATSCAMWISYFVQSIRLFMRTGSWWSFNPESNCLLNVPIGGTTVVRPLVEDSTSVTAVVTDGYLKMAGMHFGACDFQRLPSEVTVAKPNVLIALKMIKRQAYGTNSGVAIYHRYKAGNYRRPPIIQDQELALLRA
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: HISZ_PROMA
Sequence: MPIQPAFGNKDLNPQEVRKNQLISSRLSSIYERWGYEEVSPPKVERLETLTACGGISNKEIVKLVADDPIGLRPDMTASIARAASTRLAYKDRPLRLWTSGTIFKSKEDCDGKFVIEEGLQSGVELIGISDMAAEIELLYLLLDSMNQLEICSNQNPILLIGHQSILKLILSGISNDYKNKIQKYLTNYDLVETEDLDIDIEIKNKLLKVLKIRGNPSDVLDKLVNIYGSNTLFDELRRLFLIIEPISKKYGVSIQLDPTYQPHFKLYNGLIFQLICQTDYAPKVIARGGRYDDLVNSFTTSIENETGAGFSFSIDKIRELKLKVEYDDKKVARTLIAFSKSKRYEDALEKQLEIHRKGSMAMVELKPCDTKKEAEFLVNKRGFDKLVWIS
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_RHILW
Sequence: MERTCLAVILAAGDSTRMKSSKSKVLHPVAGRPMIAHVVEAVASAGISSVALVVGRDAEEVAKAASIAGVGIEACLQKERLGTGHAVLAAREAIAKGYDDILVTYGDVPLQTDGPLKAARQGLADGSDIVVIGFHTDRPTGYGRLLVKDGELIAIREEKDATDAERTVTWCNSGLMAINGRKALDLLQRIGNANAKGEFYLTDLVEIARSLGGRVTAVDAPEIEMTGCNTRAELAVIERFWQERRRHQLMLSGVTMIAPETVFLSYDTVIGQDALIEPNVVFGPGAVIDSGAVIHAFSHIEGAHVSQGATVGPFARLRPGADLGNGSKVGNFCEVKNGRIGEGAKVNHLTYIGDAVIGAGSNIGAGTITCNYDGVNKSETVIGENAFIGSNSSLVAPVTIGDGAYIASGSVITADVPADALALGRARQEIKPGRASLLRERALATKAAKKAKG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_ECO8A
Sequence: MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PSAE_GLOVI
Sequence: MAIERGAKVRILRKESYWYREVGTVASVDKSEKTIYPVTVRFEKVNYSGINTNNFGVSELEEVEA
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL17_DEHM1
Sequence: MRHNVSGRKFDRPTGQRMSLYRNLVTDLLNYEEITISEPRAKEIRSMAEKMITLGKKGTLASRRRALAFVYIPGIVDKVFEDLSKRYAERPGGYTRMTKLGPRQGDGAEMVKLELVK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ZC3H6_HUMAN
Sequence: MTDSEHAGHDREDGELEDGEIDDAGFEEIQEKEAKENEKQKSEKAYRKSRKKHKKEREKKKSKRRKREKHKHNSPSSDDSSDYSLDSDVEHTESSHKKRTGFYRDYDIPFTQRGHISGSYITSKKGQHNKKFKSKEYDEYSTYSDDNFGNYSDDNFGNYGQETEEDFANQLKQYRQAKETSNIALGSSFSKESGKKQRMKGVQQGIEQRVKSFNVGRGRGLPKKIKRKERGGRTNKGPNVFSVSDDFQEYNKPGKKWKVMTQEFINQHTVEHKGKQICKYFLEGRCIKGDQCKFDHDAELEKRKEICKFYLQGYCTKGENCIYMHNEFPCKFYHSGAKCYQGDNCKFSHDDLTKETKKLLDKVLNTDEELINEDERELEELRKRGITPLPKPPPGVGLLPTPPEHFPFSDPEDDFQTDFSDDFRKIPSLFEIVVKPTVDLAHKIGRKPPAFYTSASPPGPQFQGSSPHPQHIYSSGSSPGPGPNMSQGHSSPVMHPGSPGHHPCAGPPGLPVPQSPPLPPGPPEIVGPQNQAGVLVQPDTSLTPPSMGGAYHSPGFPGHVMKVPRENHCSPGSSYQQSPGEMQLNTNYESLQNPAEFYDNYYAQHSIHNFQPPNNSGDGMWHGEFAQQQPPVVQDSPNHGSGSDGSSTRTGHGPLPVPGLLPAVQRALFVRLTQRYQEDEEQTSTQPHRAPSKEEDDTVNWYSSSEEEEGSSVKSILKTLQKQTETLRNQQQPSTELSTPTDPRLAKEKSKGNQVVDPRLRTIPRQDIRKPSESAPLDLRLAWDPRKLRGNGSGHIGSSVGGAKFDLHHANAGTNVKHKRGDDDDEDTERELREKAFLIPLDASPGIMLQDPRSQLRQFSHIKMDITLTKPNFAKHIVWAPEDLLPVPLPKPDPVSSINLPLPPLIADQRLNRLWNTKSDLHQNTVSIDPKLAAKAKINTTNREGYLEQFGDSHGSGAKLGDPRLQKNFDPRLHRLPNTESHQVVMKDSHASKGAPHLPRSNPGSSQPSGAGTSNSGSGALPPYAPKLSSSAGLPLGTSTSVLSGISLYDPRDHGSSSTSELATASSGENSKNQKKSGGLKSSDKTEPSPGEAILPQKPSPNVGVTLEGPADPQADVPRSSGKVQVPAVHSLPVQALTGLIRPQYSDPRQARQPGQGSPTPDNDPGRETDDKSLKEVFKTFDPTASPFC
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 6.
Protein: XRN2_CRYNB
Sequence: MGVPALFRWLSKKYPKIVERVKEDTPKKIRGPDGEIVEEPIRYENPNPNGFEVDNLYLDMNGIVHPCTHPEGRPAPETEEEMMVEIFKYTERVVNMCRPRKVLMMAIDGVAPRAKMNQQRSRRFRAAQEAADKEEERREAIKLFEAMGHAVSEETANHKSWDTNAITPGTPFMDLLSISLKYWVSHKLTTDPGWKDLKIILSDSSVPGEGEHKIMDWIRRQRSYPTWDANTSHVIYGLDADLIMLSLATHEPHFRVLREDVFAQSSKGPHACKNCGKVGHIAANCKSDKKFKDPNVAEVAKTEDPKPFIFLDVACLREYLAVELVVPGMPFPFDLELAIDDWIFMIFFVGNDFLPHLPSLEIREGAIDVLLKIWRAELPRMGGYLTNHGKVNLDRAQVILEGLAKSEDEIFQKRKDDEERQEHSQKRRRIEEHKRQDEDKAREEDRNTLTLNGTEYVAVDNPAATARGGPLHPSLPSRPAFDLVPKEDAVKQPEDQDQKAKKAMAGSNSDIVKNRKAIRMANMSAAQALKAELEGGNDVNVDDKKAIAQEGKEEDEAVVTVERTEDEEKEQLTKEEARGTLEEQGEKEGVDEEVVPPAIQTDEDEGEAPVGDATVAENDESTIPEDDEDPTHVPRKRKRGDSDGDEDSNEEDDDDDDDDAPPNPEADQPIPKKKLKVNADGTVDYEDDVKLWEPGYRERYYEKKFGVKLSEREFIDKVTKSYMEGLCWVLEYYYQGVPAWDWFYPYHYAPFAQDFRDVGSMDIKFETSIPFKPFAQLLGVFPAASRIHLPEPLQTLMIDEDSPILDFYPPDFEIDMNGKKMAWQGVALLPFIDQNRLLTALKSKEELLSDDEKRRNSWGDNVMFIANENPLYDLFCDKLYGLRAKDVSKPIPIDTKASYGITGSVLPDPNCVPASTFDTPIPSISECPDLNPNDSISVRYYFPRQAHPHRSILLRGYKPEPARLTESDKDWVRRGGQGGRRGHRHNGGGNGNVTGGPGMARGRYESGPPRTNGYQPPPPRSNYGGSSGYGYGAPAPLPSRPPVSSYGGGAGGYGYSNPYAAAPNPYAGGYGAPAPYAAGGYGQRPYVPPLPPPNPYSAPPPAYGRPPGGGYGYGAPPPRGGGYNPYPSRR
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity.  Required for the processing of nuclear mRNA and rRNA precursors.  May promote termination of transcription by RNA polymerase II (By similarity).
What are the official names of this protein?
5'-3' exoribonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TIG_LEUMM
Sequence: MSKWTPAADEKNQGTLEFEIARAQVEEGLEQAFQRNKNEVSIPGFRKGKVTKQLFFQKFGEEALYQQAMDIVLPAAYEAAIDEAGITPVGRPNIEPVSMNKGEAWTLKAVVKTAPAIKLGEYLNLEVEAQDEEVADADVDAEIKRLQDGQAELVLQEESVKAENGDTVVIDFDGSVDGVKFDGGQGKDFSLALGSGQFIPGFEEQLVGHTAGEDVNVNVTFPEDYQAADLAGKEALFEVTIHELKRKELPELDDEFAKDVDEEVETLAELKEKTSKKLADEKAQAAKAAFEDAVISKAVDNASVDGDEIPAEMIDEDVHRQIDQYLGQLQQQGISREMFFQISGQTEDDLHKQFEEGAETRVKTGLILEAIVAAEKIDPSAEQVSEEVASLAAQYNMEEDKVRAAISESMLKHDIAMREAIKKVTDSAKAV
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: AROA_SHESA
Sequence: MKQLRLEPVVQVRGEINIPGSKSISNRALLLATLAKGTTTLTNLLDSDDIRHMLASLKQLGVEYRLSQNNTVCELTGLGGVISSDTAQTLFLGNAGTAMRPLCAALTLGRGEFTLTGEPRMEERPIGDLVDALKQLGANIVYLKNDGFPPLTINATGLNGGDVEIAGDLSSQFLTALLMVAPLAKGSVNIHVKGELVSKPYIDITLALMAQFGVQVINHDYARFEIPAGQQYVSPGKVLVEGDASSASYFLAAGAIKGGEVKVTGVGRLSIQGDVKFADVLEKMGADIEWGDDYIIARGAPLTAVDLDMNHIPDAAMTIATAALFAKGTTTIRNIYNWRIKETDRLAAMATELRKVGALVEEGHDYIQITPPVVLNTAEIDTYNDHRMAMCFSMMAFADCGITINDPDCTSKTFPDYFAQFASLKA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUCI_ECO8A
Sequence: MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEKLRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPTRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQGNSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NA21_STIHL
Sequence: AACKCDDEGPDIRTAPLTGTVDLGSCNAGWEKCASYYTIIADCCRKKK
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav), thereby delaying their inactivation during signal transduction (By similarity).  Is highly toxic to crabs (by intrahemocoelic injection) (PubMed:2568126, PubMed:22015268), but without effect upon mice (by intraperitoneal injection) (PubMed:2568126).
What are the official names of this protein?
Delta-stichotoxin-She1a, Delta-SHTX-She1a, Neurotoxin I, Neurotoxin Sh I, ShI, SHNA, Sh1, Toxin SHP-I.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type II subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: LEUD_ALISL
Sequence: MSGFKQHTGLVVPLDTANIDTDAIIPKQFLQKVNRTGFGKHLFHDWRFLDDAGQQPNPEFVMNAPRYQGASILLARENFGCGSSREHAPWALADYGIQVMIAPSFADIFYGNSINNQMIPVRLTDIEVDEIFQFVEANEGAEVAVDLEAMLVSANGKQYSFEIDEFRRHCLLNGLDNIGLTLQHADKISEYEAKIPNFLK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: P22_ASFWA
Sequence: MFNIKMTISVLLIALIVLLIIILVVFLYYKKQQPPKKVCKVDKDCGSGEHCVRGSCSSLSCLDAVKTDKRNIKIDSNISSCEFTPNFYRFMDTAADEQQEFGKTRHSIKITPSPSESHSPQEVCERYCSWGTDDCTGWEYDGNEKEGTCYIYNNPHHPVLKYGKNHVIALPRNHKHA
What are the official names of this protein?
Inner membrane protein p22.
What is the protein family that this protein belongs to?
Belongs to the asfivirus inner membrane protein p22 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Part of the virion inner membrane.
Protein: CBF3A_YEAST
Sequence: MRSSILFLLKLMKIMDVQQQQEAMSSEDRFQELVDSLKPRTAHQYKTYYTKYIQWCQLNQIIPTPEDNSVNSVPYKDLPISAELIHWFLLDTLITDDKPGEKREETEDLDEEEENSFKIATLKKIIGSLNFLSKLCKVHENPNANIDTKYLESVTKLHTHWIDSQKAITTNETNNTNTQVLCPPLLKVSLNLWNPETNHLSEKFFKTCSEKLRFLVDFQLRSYLNLSFEERSKIRFGSLKLGKRDRDAIIYHKVTHSAEKKDTPGHHQLLALLPQDCPFICPQTTLAAYLYLRFYGIPSVSKGDGFPNLNADENGSLLQDIPILRGKSLTTYPREETFSNYYTTVFRYCHLPYKRREYFNKCNLVYPTWDEDTFRTFFNEENHGNWLEQPEAFAFPDKIPFDFKKIMNFKSPYTSYSTNAKKDPFPPPKDLLVQIFPEIDEYKRHDYEGLSQNSRDFLDLMEVLRERFLSNLPWIYKFFPNHDIFQDPIFGNSDFQSYFNDKTIHSKGSPILSFDILPGFNKIYKNKTNFYSLLIERPSQLTFASSHNPDTHPTQKQESEGPLQMSQLDTTQLNELLKQQSFEYVQFQTLSNFQILLSVFNKIFEKLEMKKSSRGYILHQLNLFKITLDERIKKSKIDDADKFIRDNQPIKKEENIVNEDGPNTSRRTKRPKQIRLLSIADSSDESSTEDSNVFKKDGESIEDGAYGENEDENDSEMQEQLKSMINELINSKISTFLRDQMDQFELKINALLDKILEEKVTRIIEQKLGSHTGKFSTLKRPQLYMTEEHNVGFDMEVPKKLRTSGKYAETVKDNDDHQAMSTTASPSPEQDQEAKSYTDEQEFMLDKSIDSIEGIILEWFTPNAKYANQCVHSMNKSGNKSWRANCEALYKERKSIVEFYIYLVNHESLDRYKAVDICEKLRDQNEGSFSRLAKFLRKWRHDHQNSFDGLLVYLSN
What is the function of this protein?
Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules.  CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA.  It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromers and in several promoters.
What are the official names of this protein?
Centromere DNA-binding protein complex CBF3 subunit A, Centromere-binding factor 2, Chromosome transmission fidelity protein 14, Kinetochore protein CTF14.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Spindle midzone during anaphase B.
Protein: RBFA_BORAP
Sequence: MYKNIKKFKLESFIAQEIGNLIVSRGIKDPRIHSFLTVVKVEFSKDLINAKVFIGSIKEGASLDNAVKALNNAKGFIQSQIIKRIKVRSTPKLLFVKDDSLSKSFYVNKIIEGLNTIREN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC46_MACFA
Sequence: MSGAKSAQGPEEGGVCITEALITKRNLTFPEDEELSEKMFHTLDELQTVRLDREGITTIRNLEGLKNLHSLYLQGNKIQQIENLACVPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDSYRELVIEALPLLLDLDGQPVMERWISDEEDEASSEEEFPELSGPFCSERGFLKELEQELSRHREHRQQAALTQHLLRMEMQPTLTNLPLLPGVPMAGDSSPSTTPGQGEETVPEAVSSPQASSPTKKPCSLIPRGRQNSLWGRKGVRASTVPKASVAEAPSTTKTMAKRSKK
What are the official names of this protein?
Leucine-rich repeat-containing protein 46.
Protein: MSP78_CAEEL
Sequence: MAQSVPPGDIQTQPGTKIVFNAPYDDKHTYHIKVINSSARRIGYGIKTTNMKRLGVDPPCGVLDPKEAVLLAVSCDAFAFGQEDTNNDRITIEWTNTPDGAAKQFRREWFQGDGMVRRKNLPIEYNP
What is the function of this protein?
Central component in molecular interactions underlying sperm crawling.  Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
What are the official names of this protein?
Major sperm protein 78, MSP.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasm, cytoskeleton.
Protein: RS5_HELHP
Sequence: MEINREEFSEVVVNIGRVTKVVKGGRRFRFNALVVVGNKNGLVGFGLGKAKEVPDAIKKAIDDAFKNIIKVNIKGTTIAHDIEHKYNASRILLKPASEGTGVIAGGSTRPVIELAGIKDILTKSLGSNNPYNVVRATIDALARIKA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: LPXA_BURP1
Sequence: MSRIHPTAIIEPGAQLHETVEVGPYAIVGSHVTIGARTTIGSHSVIEGHTTIGEDNRIGHYASVGGRPQDMKYKDEPTRLVIGDRNTIREFTTIHTGTVQDTGVTTLGDDNWIMAYVHIGHDCRVGSHVILSSNAQMAGHVEIGDWAIVGGMSGVHQFVRIGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRILYKNSLSLEEAKVQLSELAQAGGDGDAAVKSLVDFVESSQRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_SULIL
Sequence: MSLQQKIKAYLKLGKLGVVSLLDLAAVAGAFLAYKHGISLLPIIPMFIGGTLASMGAMIINSGIEIDRDKVMSRTSKRPTVVGYVNRKEAIIVGSLLAILGTALGFIDNILTAFFIALGVVIYIFVYTILLKPRTWLNIVIGGFAGSAAAWAGYTSLTNSLTLEGFLLGFLIFMWTPGHFWSLALKYREDYVNAHYPMLPAVVGITTSARAIAISNALMIPIVLLLGYYINLIALIAFSILSLFLMFLSYRLILNPTKEEAIKSFIFSNIYLMLILLIMIIVKLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DLTC_LISMO
Sequence: MAFRENVLEILEEITETDEVVQNTNIKLFDEGLLDSMATVQLLIEIEEKLDITVPVSEFDRDEWATPEMIITQLEALK
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.