PharMolix/UniProtQA huggingface dataset:
Protein: RL27_BACMK
Sequence: MLRLDLQFFASKKGVGSTKNGRDSQSKRLGAKRADGQTVSGGSILYRQRGTKIYPGVNVGRGGDDTLYAKVDGVVRFERLGRDRKQVSVYPVAQEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CALL4_XENTR
Sequence: MAKFLSQDAIQKFKECFSLYDKKGKGKIPAGDLLTVMRCLGTCPTPGEVTRHLQVHKIGKDGEVDFSTFLTIMYRQQKQEDPENEIMVAMLMSDKQKKGVIPLKELRAKLTQMGEKLTPEEVDDLLKGVKVGPDGMVKYEEFVRQITLPVPDY
What are the official names of this protein?
Calmodulin-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: SYC_STACT
Sequence: MITLYNTLTRQKEPFEPLEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYKGYDVNYVSNFTDVDDKLIKRSKELNESVPEIADRYIQAFYEDTGALNVKKATSNPRVMNHMDDIIEFIKDLVDKGYAYESGGDVYFRTRKFEGYGKLSHQSIDDLKVGARIESGEQKEDALDFTLWKKAKPGEISWDSPFGKGRPGWHIECSVMAYNELGETIDIHAGGSDLQFPHHENEIAQSEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFVLVHDIIKEVDPDVLRFFMISVHYRSPINYNMELVESAKSGLERIRNSYQAIEEREAIATDIEDQSEYIEQIDQLLAQFEKVMDDDFNTANAITTWYDLAKLANKYVLENTTSKKVIERFKEVFQIFSDVLGIPLKGKQQDELLDEDIEALIEERNEARKNKDFARADEIRDQLKAQNIILEDTAQGVRFKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_RHIME
Sequence: MARYVFITGGVVSSLGKGIAAAALGALLQARGYRVRLRKLDPYLNVDPGTMSPTQHGEVFVTDDGAETDLDLGHYERFTGRSATKTDNITTGRIYKNIIDKERRGDYLGATVQVIPHVTNEIKNFVTEGNEDYDFVICEIGGTVGDIEAMPFMEAIRQLGNDLPRGTAVYVHLTLMPYIPAAGELKTKPTQHSVKELQALGIHPDILLVRADREIPEAERRKLSLFCNVRQSAVIQALDVASIYDVPIAYHKEGLDNEVLAAFGIEPAPKPRMEAWEDVAHRIRTPEGEVTIAIVGKYTGLKDAYKSLIEALYHGGIANRVKVKLEWIESEVFEKEDPAPYLEKVHGILVPGGFGERGSEGKINAARFARERKVPYFGICFGMQMAVVEAARNLAGIEKASSTEFGPTKEPVVGLMTEWVKGNELEKRSAAGDLGGTMRLGAYRAALKPDTKIAGIYGSPDISERHRHRYEVNVDYKSRLESCGLVFSGMSPDGVLPETIEYPDHPWFIGVQYHPELKSRPLDPHPLFSSFIEAALEQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PXDC1_MOUSE
Sequence: MASAVFEGTSLVNMFVRGCWVNGIRRLIVSRRGDEEEFFEIRTEWSDRSVLYLHRSFADLGRLCKRLRDAFPEDRSELARTPLRQGLLAIKGAHDIETRLNEVEKLLETVISMPCKYSRSEVVLTFFERSPLDQVLKNDNVHKIQPSFQSPVKISEIMRSNGFCLANTETIVIDHSIPNGKDQLLDADSTEHLFENGGEFTSELEDGDDPEAYVTNLSYYHLVPFETDILD
What are the official names of this protein?
PX domain-containing protein 1.
Protein: QUEE_HYPBU
Sequence: MSRSARRKTSALNTVLRVVEVFASIQGEGPFTGTYSVFVRLAGCNLRCPFCDTRYAWSLEAGKPLGVEELVEEIARYEPSLVVITGGEPLLQRHPLNSLVEGLESLGLRVQLETNGILPAPARDEQLWRVYHVVSPKDVPVRVPGAKLHPSWVDYARATGRAWFKFLVANEQHVREVAEYVAKLGIPRSRVYIMPLTPEKLDMKELLELHSRIASLAVKWRLNFSPRLHLLVQLP
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Archaeosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: KDSB_ERWT9
Sequence: MSFVAIIPARFASTRLPGKPLVDIHGKPMVVHVMERALESGAERVIVATDHIDVAHAVEAAGGEVCMTRADHQSGTERLAEVIDHYQFPDDKVIVNVQGDEPMIPPVIIQQVAKNIAQRSVGMATLAVPVDSVEEAFNPNAVKVVRDAQGNALYFSRATIPWDRERFAVSQDSIGDNFLRHIGIYGYRAGFIRRYVRWEASPLEQIELLEQLRVLWYGEKIHVDVAQAIPSAGVDTAEDLQRVRAAMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_OENOE
Sequence: MASLQDIRRRIDSTKKTSQITSAMQMVSSSKLIQIQKHTSGYLDYANHVEAIVAHLAAAHLLEHQNGSSIPFITQRPVKTTAILVITSDRGLVGGYNNQVLKRTDQIMREQKLTKENAVIFALGGKGSDYYAKRGFTIAFENRDITDVPKFWEVSDLVKEVTKQYAARKFDALELVFNHFINRLKNDVVNQQILPIRSENFQRDEKGNLTADKYKGQSSIYEFEPAPESLLKIVLPQFAQSLLYGAILDAKTAEHAASASAMRAATDNAKDLISTLELKYNRARQAAITTEITEITGGMAALQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL1_SULSY
Sequence: MAKRGKKYLEALKLIDKEKTYSLDEAIQKLKEVEKILQRKFDETVELIFRLGVDPKYADQMVRGSVVLPHGLGRELKVLVIASGEKLKEAEEAGADYAGGEEIINKIANENWIDFDIVIATPDMMPKLAKLGKILGPRGLMPNPKVGTVTTDVKRAVTEAKKGRVEFKVDKTGNLHVPVGKISFEDHKLKENILAVVDAVLKAKPPGAKGQYIRNVVLKTTMSPSVKLNPAELQKALETKAA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TRPA_HAEI8
Sequence: MSRFETQFATLNAKNEGAFVPFVTLCDPTFDCSFEIICTLVDNGADALELGFPFSDPLLDGPVIQAANNRALTAGHSSEDSFKLLEKVRSKYPEIPISLLLCANLIFAKGLDAFYQRCAEVGVDAVLVADIPLLAKEDYVQAAKKHGIQPVFICPPNADEKTIQGVAKNSEGYTYLVSRAGVTSAENQAHAANLDTLVEQLKAHYAPPILQGFGIAQPAQVKEALALGAAGAISGSATVKIIERNLDNHEQCLAELAEFVQTMKAATK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: GADW_ECOL6
Sequence: MAHVCSVILVRRSFDIHHEQQKISLHNESILLLDKNLADDFAFCSLDTRRLDIEELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPIQLVTAIFDSFNDPRVNSPILSKMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAERMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYFINTFRQYYGVTPHQFSQHSPGTFS
What is the function of this protein?
Depending on the conditions (growth phase and medium), acts as a positive or negative regulator of gadA and gadBC.  Repression occurs directly or via the repression of the expression of gadX.  Activation occurs directly by the binding of GadW to the gadA and gadBC promoters (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator GadW.
Protein: TRMY_METVS
Sequence: MKEFIIKANKAVTNGEINLKDLPGSSGRLDLICRCVNSAFFLSHDLRRDTIFYSVNYGNPNPPVALKFIGDELKRLSPDERSIAMFIQKALSKDASEIWKESTSGIYYSNHEFKEIILEKKNSGKKIFYLHLNGKPLENFDFKNESDVVFILGDHIGLSKEDEEFLEEIGAEQISLSPLELHADHCIILVHNVLDRLK
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_LACH4
Sequence: MEYTEVMVRYGELSTKGKNRKDFINRLASNVEKVLKDLPQIDFHPRHDRMHIVLNGAPFAEVDKRLKKVFGIQTYSPAIKIPKTLEDIEKTSLELMQETFKPGMTFKVNTKRSDHKFEYDTNQLNNLVGDYLFDHIDHLKAEMKHPDLVLRIEVRQDAVYISNQLLHGIGGMPVGTAGKAVMMLSGGIDSPVASYLAMKRGVDIEMVHFFSPPYTTEKALAKAKELTGILANYVGKINFIAVPFAEIQETIKEKLPEGYLMTVQRRFMLQLADRIRAKRGGLAIFNGESVGQVASQTLQSMVAINDVTTTPVIRPVATMDKTEIIKLAEDIGTFDLSIQPFEDCCTIFAPPRPKTKPKLDKAREYEARLDVEGLIQRAMDGIEVMPIYPNEKFINDKIEEDQDLL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM_AGABI
Sequence: MAHVLPDLPYAYDALEPYISRQIMELHHKKTSSDLCECAQHCRGCLRHSTAVVGGFDLSLFFILTTLGHINHSLFWQNLAPAAGAGGQLKPGPLKDAIDQTFGGLDNLKKEFNTTTAGIQGSGWGWLGVNPSNKRLEISTTPNQDPLLNLVPIIGVDIWEHAFYLQYLNVKADYLNAIWSVINFDEAQRRYVEATQGSKL
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: KPYK_STAAC
Sequence: MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PEP-utilizing enzyme family.
Protein: Y2008_SHEON
Sequence: MQERGLVGLGLRREMLSEFCQQLPSAIDFLEVAPENWMTLGGKYGKQFRQLTEQHTFFCHGLSLSIGSPEPLDLEFVRRIKAFMDLHQIDVYSEHLSYCSGAGHLYDLMPIPFTEAAVKHVARRVKQVEDILERPLILENVSFYAAPSAQMTELAFLTAVLEEADCKLLLDVNNIYVNSINHQYDALAFLKAMPTERIAYLHIAGHFKESEELLIDTHGSDINAPVWALLDSCYAEHGVLPTLLERDFNLPATAHLLDEINQIHAYQARAKSNLDKRIA
What are the official names of this protein?
UPF0276 protein SO_2008.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.
Protein: FLIW1_HELPY
Sequence: MNYFLKAPILGFEHINEVRLEKIDSLFSRLISQTNSPMALDMVLVNPYCLREYSFVIPKYIELLLELDSHSKVEVYCVVVLQKNLEDSMVNFLAPLVFNSKNGFGAQVALSMMDYPDFGFRDPLKSFVIQERERA
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW 1.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_ECO45
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQENTPKPQNASAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RUVC_PARUW
Sequence: MSNQVIILGLDPGTKITGFGVIRIEGHQYVPVDYGCIRPPSHYKLSERYLVICQGVEQLIDQHQPHAVVVETQYVSKNVQSAMKLGMARGVIMIAAKKRGIPIYEYAPSKAKLAVVGTGRASKYQVQGMVQRLLNLSIPPTPEDAADALALAICHAQMPILKQSQYET
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RL18_AGRRK
Sequence: MASRKEALARRANRVRRQLKSVANGRPRLSVHRSSKNIYVQVIDDAAGKTLASASTLDKDLRGSLKTGADTAAAALVGKLVAERATKAGVKEVVFDRGAFIYHGRIKALAEAAREGGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PHNS_DESDA
Sequence: MRIAVGLGKEGGEERLERQGISRRDFMKFCTAVAVAMGMGPAFATDVAAALTGRRPSVVYLHAAECTGCSEALLRTYQPFIDTLILDTISLDYHETIMAAAGEAAEEALQAAVNGPDGFICLVEGAIPTGMDNKYGYIAGHTMYDICKNILPKAKAVVSIGTCACYGGIQAAKPNPTAAKGINDCYADLGVKAINVPGCPPNPLNMVGTLVAFLKGQKIELDEVGRPVMFFGQSVHDLCERRKHFDAGEFAPSFNSEEARKGWCLYDVGCKGPETYNNCPKVLFNETNWPVAAGHPCIGCSEPNFWDDMTPFYQN
What are the official names of this protein?
Periplasmic [NiFe] hydrogenase small subunit, NiFe hydrogenlyase small chain.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS13_CHLAD
Sequence: MARIAGVDIPRNKKIEIAITYIYGIGRSNGMDVLRKANVDPNRRVRDLTEEEVGRIREIIDREYRVEGDLRREVQLNIKRLMDIGCYRGLRHRRGMPVRGQRTRTNARTRRGRRGQAIGIKKKVKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GLMM_SHEPC
Sequence: MKERKFFGTDGIRGKVGSGQMTPELALKLGWAAGRVLSRSGTKKVIIGKDTRISGYMFESALEAGLSAAGLNVMLMGPMPTPAVAYLTRTFRAEAGVVISASHNPYYDNGIKFFSTDGSKLDDNLELEIEAELEKPLVCVESHLLGKVSRIEDARGRYIEYCKGNFPAEHTLTGLKIVVDCAHGATYHIAPAVFRELGAEVIAIGDKPNGMNINDKVGATSMGKICETVLAESADLGIALDGDGDRIMMVNSKGEVIDGDQILYILACDAKSRGVLRGGVVGTLMSNLGLDLALQALDIPFARSKVGDRYVMELLKELDWRIGGENSGHILNLDHGTTGDGIIAGILVLAAMRRQNATLEELTSAMEMLPQVLVNVRFEGEHDPLKSDKVKVAQAQVESQLGVRGRVLLRKSGTEPLIRVMVEGDDHSAVLAHANLIADAVKSAS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: GABP1_MOUSE
Sequence: MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHFSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHANIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAATPQFIIGPGGVVNLTDETGVSAVQFGNSSTSVLATLAALAEASAPLSNSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGMGQPIIVTMPDGQQVLTVPATDIAEETVISEEPPAKRQCMEIIESRVECAEIEEREALQKQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRIQTNKEAV
What is the function of this protein?
Transcription factor capable of interacting with purine rich repeats (GA repeats) (PubMed:25200183).  Acts as a a master regulator of nuclear-encoded mitochondrial genes (PubMed:25200183).
What are the official names of this protein?
GA-binding protein subunit beta-1, GABP subunit beta-1, GABPB-1, GABP subunit beta-2, GABPB-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: COX1_CANLU
Sequence: MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFAHWFPLFSGYTLNDTWAKIHFTIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTTWNTVSSMGSFISLTAVMLMIFMIWEAFASKREVAMVELTTTNIEWLHGCPPPYHTFEEPTYVIQK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KDSB2_HYDCU
Sequence: MKTYVFIPARYGSSRLPGKPLKLINGKPMIQHVFERISKATGIEAVYVATDDDRIKEVVEKFGGNVVMTPPEAESGTDRIAQAAQALDLKEDDLIVNVQGDQPLVNQGSIEAVIAPFKAADYDGSFEMSTLSFKIVNEAEITSPKDVKLVTDVNGFALYFSRATIPHGRDYWDHDSYKHLGVYAYTKRFVDLFNTLPMGHLEDIEKLEQLRALEYGHKIKVVESEWDSPEVDLPGDIEMMEALLNAGH
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase 2, CMP-2-keto-3-deoxyoctulosonic acid synthase 2, CKS 2, CMP-KDO synthase 2.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_BACAA
Sequence: MYAIIETGGKQIKVEAGQAIYIEKLDVEAGETVTFDKVLFVGGENVKVGSPVVEGATVTAKVEKQGRAKKIIVFKYKAKKNNRKKQGHRQPYTKLVVEAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GLPQ1_MYCTU
Sequence: MTWADEVLAGHPFVVAHRGASAARPEHTLAAYDLALKEGADGVECDVRLTRDGHLVCVHDRRLDRTSTGAGLVSTMTLAQLRELEYGAWHDSWRPDGSHGDTSLLTLDALVSLVLDWHRPVKIFVETKHPVRYGSLVENKLLALLHRFGIAAPASADRSRAVVMSFSAAAVWRIRRAAPLLPTVLLGKTPRYLTSSAATAVGATAVGPSLPALKEYPQLVDRSAAQGRAVYCWNVDEYEDIDFCREVGVAWIGTHHPGRTKAWLEDGRANGTTR
What is the function of this protein?
Glycerophosphodiester phosphodiesterase hydrolyzes glycerophosphodiesters into glycerol-3-phosphate (G3P) and the corresponding alcohol.
What are the official names of this protein?
Probable glycerophosphodiester phosphodiesterase 1, Glycerophosphoryl diester phosphodiesterase 1.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
Protein: C85CA_DANRE
Sequence: MAKNITDVSRDDLSKVSDEELQKCSKEELLRRLRKVDAEKMNLMLEHGNMMKDVNRRLQLHLHEIRSLKEVNQKLQEDNQELRELCCFLDDDRQKGKKLSREWQRFGRYTASVMWKEVGVFQQKLKELESNQDSVMRENLELKEIIIMLDDERNGAGSRSSIDSQSSLSNLNGGSATVRDVGDGSSTSSTGSAGSPDHHHSHIHKPTEGKITSIRRSMDDLSTNHLLRNIPNGLNDSSSNYIRQLETKVRILEDDNKQLLSQQGSVGDLKTLRKGLSLYHSESQLSSLSQFQDTLQNGSIRIAGGDLAPTVTGYLPAAQKPEAVVHAMKVLEVHENLDRKIPEDYEEDLSEKEKAIVREMCNVVWRKLGDAAGTKPSIRQHLSGNQFKGPL
What is the function of this protein?
May play a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity).  May play an important role in cortical development, especially in the maintenance of radial glia (By similarity).
What are the official names of this protein?
Coiled-coil domain-containing protein 85C-A.
What is the protein family that this protein belongs to?
Belongs to the CCDC85 family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell junction, adherens junction.
Protein: LPF_SHIFL
Sequence: MKHIPFFFAFFFTFP
What is the function of this protein?
This protein is involved in control of the biosynthesis of phenylalanine.
What are the official names of this protein?
phe operon leader peptide, phe operon attenuator peptide.
Protein: UP44A_XENLA
Sequence: MDKCKHVGRLRLAQDHSILNPQKWHCVDCNTTESVWACLSCSHVACGRYIEEHALRHFQDSKHPLALEVNELYVFCYLCDDYVLNDNTTGDLKLLRSTLSAIKSQNYDCTTRSGRTLRSMVTADDSFISHEGAQAFLQNEDRAFTALWHRRHALLGKVFRSWFALTPKGKQRLEEERLREEAEQKREEARKKRQQLKRKLKEEMESTSPRKSSRLQHQIQPSPKTELPSVQKMNQKNSPTTKQKTPAPTSDKACFKKIGNSPIKRKPTVTPGVTGLRNLGNTCYMNSILQILSHLHVFRECFLQLDLNQTQELLAAAGSGKTRLSSKYPPGAELPRVTQKHTKVQRSLARRQSFSLGLSGGASNSRNMELIQPKEPSSKHISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKVQQELETTGTRYPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLVCDHKSNTIEPFWDLSLEFPERYHFNGKETASQRPCLLTEMLAKFTETEALEGKIYACDQCNKAQKQLMVCRLPQVLRLHLKRFRWSGRNHREKIGVHVRFDQMLNMEPYCCRESTAALRADCFIYDLSSVVMHHGKGFGSGHYTAFCYNPEGGFWVHCNDSKLHSCTVEEVCKAQAYILFYTQRVTQENGHLSDTLPVHGSPQSPPR
What is the function of this protein?
Deubiquitinase that plays a key role in the spindle checkpoint by preventing premature anaphase onset.  Acts by specifically mediating deubiquitination of cdc20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C) (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 44-A, Deubiquitinating enzyme 44-A, Ubiquitin thioesterase 44-A, Ubiquitin-specific-processing protease 44-A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP44 subfamily.
What are the subcellular locations of this protein?
Nucleus.