PharMolix/UniProtQA huggingface dataset:
Protein: TRPE_METTH
Sequence: MNVFGITELKNPVKEKIEFKEPFELFKSIYSEYDSSFLLESMESDTGLARYSFMGFEPQMIIRARSGFIEVEYEGSREEFDTENPFEFLRQFTRPAGKSRGFCGGLVGYISYQAARFFDSINLSPGNFPDFEFGLFLDGIMFNHLTGECSYISLKENRLPEISELLREETPTGHLKYRSMGTLFSRRRYLGMVEEARERIAEGEIFQAVLSNATDYRLRGDRLALYEALRRVNPSPYMYHLKLGSREITGSSPEMLVRVEDKQIETFPIAGTRPRGKTPHEDERIAAELLSDEKELAEHLMLVDLARNDLGRISEFGTVQVPEYMTIRRFSHVQHILSHVTGRLRKGMDALDALGAVFPAGTVSGAPKIRAMEIIESLEGVPRNAYAGALGYLSLNGNADFAITIRSMVAEGAYGRIQAGAGIVHDSVPEREYVECQNKAMAVLKSMELAGDGFDSDEPFIARR
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: SP13B_ARATH
Sequence: MDWNFKLSSGYLSGFDQEPDLSPMDGSISFGGSSQSKADFSFDLKLGRNIGNSSSVFGDTEQVISLSKWKDSALAKPEGSRSSSSKRTRGNGVGTNQMPICLVDGCDSDFSNCREYHKRHKVCDVHSKTPVVTINGHKQRFCQQCSRFHALEEFDEGKRSCRKRLDGHNRRRRKPQPEHIGRPANFFTGFQGSKLLEFSGGSHVFPTTSVLNPSWGNSLVSVAVAANGSSYGQSQSYVVGSSPAKTGIMFPISSSPNSTRSIAKQFPFLQEEESSRTASLCERMTSCIHDSDCALSLLSSSSSSVPHLLQPPLSLSQEAVETVFYGSGLFENASAVSDGSVISGNEAVRLPQTFPFHWE
What is the function of this protein?
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'.
What are the official names of this protein?
Squamosa promoter-binding-like protein 13B.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMA_XANOR
Sequence: MNSSFSAPAKKSLGQHFLADRYYIDRIVQAVDPRAGQHLVEIGPGQGAITFPLLRKHGALTVIEFDRDLIAPLTEAAAPIGALSIIHRDVLSVDFTALADGTPIRLVGNLPYNISSPILFHALDHAAVVADMHFMLQKEVVDRMAAGPGSKVYGRLSVMLQAYCDVTALFVVPPGAFRPPPKVDSAVVRLVPRDPATVHINDRRRFADVVRAGFGQRRKTLRNALSTVCEPAHFEAAQVRPDARAEQLEVADFIRLANVEPA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGP1_SCHPO
Sequence: MSKVNMRALLESFSTVILSIYPLAKSTNQQSHSHSLSLTQFLYETIRRSRVDYTTLLLALYYFIRFRDAASSKPTNYIPLLCGRRLFLVCLMAATKFLQDRSFSNRAWSRLSGLPVDKLLVLEYMFYQCIDYRLVVPKHIFARWSLLVGECCAHATARYDSTDPNVASFGSVAQYWVSLFSNVQSSLDDLFSIACLTKIAHRRMNANAALKNQATRKPSSSPQTTQDSSPILTMAPSTPVSVGSTPPSTPSVLPIAKQLAPMNVCKAHIQASNQSRTLTTASPPEQIPLMEPQVYVNPQVLPGRLSSLSKPVSLPPTPSSPKVGVYRPMTSKSNGGVAYCYNAQKLNNATGPVTFNMPFASVLPLAVSVSCDLGTASAYVASLPQPCSQKRHLEEDYSCLTEHSAKRRSYF
What is the function of this protein?
Essential for the control of the cell cycle at the G1/S (start) transition.  Interacts with the pef1 protein kinase.  The pef1/pas1 complex activates the res2/cdc10 complex.
What are the official names of this protein?
G1/S-specific cyclin pas1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
Protein: FOLD_PASMU
Sequence: MTAQVISGTELSKTIKSQVAQKIETYTQQGKRSPGLAVILVGADPASQVYVGSKRKSCAEIGIQSKSYDLPETTQESELLALIDELNADTTVDGILVQLPLPKHIDSTKVIERITPEKDVDGFHPYNVGRLCQRIPTLRACTPYGVMKLLETTGIDLHGKHAVIVGASNIVGRPMALELLLAGCTVTVTHRFTKDLAHHVRQADILVVAVGKPKFIPGDWIKAGAIVIDVGINRQEGKLVGDVEYDVALEKAGYITPVPGGVGPMTVAMLMFNTLSAYEMKIAS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: FBXW7_HUMAN
Sequence: MNQELLSVGSKRRRTGGSLRGNPSSSQVDEEQMNRVVEEEQQQQLRQQEEEHTARNGEVVGVEPRPGGQNDSQQGQLEENNNRFISVDEDSSGNQEEQEEDEEHAGEQDEEDEEEEEMDQESDDFDQSDDSSREDEHTHTNSVTNSSSIVDLPVHQLSSPFYTKTTKMKRKLDHGSEVRSFSLGKKPCKVSEYTSTTGLVPCSATPTTFGDLRAANGQGQQRRRITSVQPPTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCKEEGIDEPLHIKRRKVIKPGFIHSPWKSAYIRQHRIDTNWRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:22748924, PubMed:17434132, PubMed:26976582, PubMed:28727686, PubMed:35395208).  Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter brings them to the SCF complex for ubiquitination (PubMed:22748924, PubMed:26774286, PubMed:17434132, PubMed:26976582, PubMed:28727686).  Identified substrates include cyclin-E (CCNE1 or CCNE2), DISC1, JUN, MYC, NOTCH1 released notch intracellular domain (NICD), NFE2L1, NOTCH2, MCL1, RICTOR, and probably PSEN1 (PubMed:11565034, PubMed:12354302, PubMed:11585921, PubMed:15103331, PubMed:14739463, PubMed:17558397, PubMed:17873522, PubMed:22608923, PubMed:22748924, PubMed:29149593, PubMed:25775507, PubMed:28007894, PubMed:26976582, PubMed:28727686, PubMed:25897075).  Acts as a negative regulator of JNK signaling by binding to phosphorylated JUN and promoting its ubiquitination and subsequent degradation (PubMed:14739463).  Involved in bone homeostasis and negative regulation of osteoclast differentiation (PubMed:29149593).  Regulates the amplitude of the cyclic expression of hepatic core clock genes and genes involved in lipid and glucose metabolism via ubiquitination and proteasomal degradation of their transcriptional repressor NR1D1; CDK1-dependent phosphorylation of NR1D1 is necessary for SCF(FBXW7)-mediated ubiquitination (PubMed:27238018).  Also able to promote 'Lys-63'-linked ubiquitination in response to DNA damage (PubMed:26774286).  The SCF(FBXW7) complex facilitates double-strand break repair following phosphorylation by ATM: phosphorylation promotes localization to sites of double-strand breaks and 'Lys-63'-linked ubiquitination of phosphorylated XRCC4, enhancing DNA non-homologous end joining (PubMed:26774286).
What are the official names of this protein?
F-box/WD repeat-containing protein 7, Archipelago homolog, hAgo, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, SEL-10, hCdc4.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus, nucleoplasm. Chromosome. Note=Localizes to site of double-strand breaks following phosphorylation by ATM. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus, nucleolus.
Protein: RECO_GLOVI
Sequence: MSGKTYRATGINLRRMPLGESDLLMTILTRENGLVRAVARGARKANARIGGRTEQFVVNDLQLYRGRSLDQLTQAESLRTFPGLLQDLGRLTAAQYLAEGVLQEATEGQAQEDLYDLLLVHLERLAATPSHQIAARLVHGVYQLLAVGGVAPEVHFCTVSHRPISAESAGFSVEGGGLVALECLSHERVGFRLDIEQVAALQLLADADLTPASLDWNYLWIGLERLLRRHIEFHFDRPLRAATLLEICFEPLAVPAAASPQ
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RBSD_SALDC
Sequence: MKKGTVLNSEISSVISRLGHTDTLVVCDAGLPIPNSTARIDMALTQGVPSFMQVVDVVTREMQVEAAILATEIKQQNPQLHETLLTHLEQLQQHQGNTIKISYTTHEQFKKLTADSQAVIRSGECSPYANVILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR8_HELSJ
Sequence: MPRDLFSDALTRLRNALRVNKQTVIIPFSNLNYSFSNILLEEHLLEKKTILSKKYIKLEGLKFYNKKSDHTLFNFFKNCQRLSKPSNRLYIKAGDIPLIDNGLGFVILSTSYGLMTGKKARALNIGGELLCQFNFQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid.
Protein: CHST4_HUMAN
Sequence: MLLPKKMKLLLFLVSQMAILALFFHMYSHNISSLSMKAQPERMHVLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRAVFLCDMSVFDAYMEPGPRRQSSLFQWENSRALCSAPACDIIPQDEIIPRAHCRLLCSQQPFEVVEKACRSYSHVVLKEVRFFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSRERTKGDLMIDSRIVMGQHEQKLKKEDQPYYVMQVICQSQLEIYKTIQSLPKALQERYLLVRYEDLARAPVAQTSRMYEFVGLEFLPHLQTWVHNITRGKGMGDHAFHTNARDALNVSQAWRWSLPYEKVSRLQKACGDAMNLLGYRHVRSEQEQRNLLLDLLSTWTVPEQIH
What is the function of this protein?
Sulfotransferase involved in SELL/L-selectin ligand biosynthesis pathway.  Catalyzes the transfer of the sulfate group from 3'-phospho-5'-adenylyl sulfate (PAPS) onto the hydroxyl group at C-6 position of the non-reducing N-acetylglucosamine (GlcNAc) residue within O-linked mucin-type glycans.  Contributes to generate sialyl 6-sulfo Lewis X determinant (also known as MECA-79 epitope) for SELL recognition, a prerequisite for continuous lymphocyte homing into peripheral lymph nodes and antigen immune surveillance (PubMed:11439191, PubMed:12107080, PubMed:10330415, PubMed:11726653).  Transfers the sulfate group primarily on core 2 GlcNAcbeta1-6(Galbeta1-3)GalNAcalphaSer/Thr and extended core 1 GlcNAcbeta1-3Galbeta1-3GalNAcalphaSer/Thr based O-linked glycans on CD34 and GLYCAM1 peripheral node addressins (PNAds) expressed on the lumenal side of high endothelial venules (HEVs) (PubMed:11439191).  The recognition of PNAds by SELL initiates a multistep process comprising tethering and rolling of blood lymphocytes on HEVs against the blood flow, followed by chemokine signaling, integrin-mediated lymphocyte adhesion onto endothelial cells and lymphocyte transendothelial migration.  Modulates rolling velocity and differential T and B lymphocyte recruitment into peripheral lymph nodes, with a major role in B lymphocyte homing.  Might be redundant in sulfation of MADCAM1 and lymphocyte trafficking to mesenteric lymph nodes (By similarity).  Can also sulfonate core 3 GlcNAcbeta1-3GalNAc-R based glycans as well as GlcNAcbeta1-3Galbeta1-Glc, GlcNAcbeta1-6ManOMe and GlcNAcbeta1-2Man oligosaccharides, which might be ectopically expressed during tumorigenesis (PubMed:12107080, PubMed:11439191, PubMed:11726653).
What are the official names of this protein?
Carbohydrate sulfotransferase 4, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3, GST-3, High endothelial cells N-acetylglucosamine 6-O-sulfotransferase, HEC-GlcNAc6ST, L-selectin ligand sulfotransferase, LSST, N-acetylglucosamine 6-O-sulfotransferase 2, GlcNAc6ST-2, Gn6st-2.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: TESE_COMTE
Sequence: MSDKQFIETQGQRLYEALRSARTLAPLTDNHPEMTVEDAYHISLHMLRLREASGERVIGKKIGVTSKPVQDMLNVHQPDFGFLTDSMEYEDGAAVSLKAAGLIQPRAEGEIAFMLKKDLQGPGVTREDVLAATEWVAPCFEIVDSRINDWKIKIQDTVADNASCGVFVIGKQHTDPASLDLAAAAMQMSKNGQPAGSGLGSAVQGHPAEAVAWLANTLGAFGIPFKAGEVILSGSLAPLVPAAAGDRFDMVIEGMGTCSIQFTE
What is the function of this protein?
Involved in the catatabolism of testosterone.  Catalyzes the hydration of 2-hydroxyhexa-2,4-dienoic acid to 4-hydroxy-2-oxohexanoic acid.
What are the official names of this protein?
2-hydroxyhexa-2,4-dienoate hydratase.
What is the protein family that this protein belongs to?
Belongs to the hydratase/decarboxylase family.
Protein: NIFB_METJA
Sequence: MDKNKMSKFAHITKVHPCFNEKIHDKVGRVHLPVAPRCNIACKFCRRSLGKEACEHRPGVALSVLKPEDVESYLNKVLKEIPNIKVVGIAGPGDSLFNKETFETLKIIDEKFPNLIKCLSTNGLLLNKYYKKLADLNVKTVTVTVNAIDPEILKEIVEWVYYDKKVHYGIEGAKILIENQIDGIKKAYDEDLIIKINTVLIPEINMNHVVDIAKELKDFVYIQNIIPLIPLYKMSHLRPPTCEELKKVREECEKYIPQFRACGQCRADAVGLIKERKILEEFFKEKNKKLNVFELKHFSH
What is the function of this protein?
Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms.  NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.
What are the official names of this protein?
FeMo cofactor biosynthesis protein NifB, Nitrogenase cofactor maturase NifB, Radical SAM assemblase NifB.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. NifB family.
Protein: FLP19_CAEEL
Sequence: MSFQLTLFSMLFLLIAVVVGQPIQSQNGDLKMQAVQDNSPLNMEAFNDDSALYDYLEQSDPSLKSMEKRWANQVRFGKRASWASSVRFG
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.  WANQVRF-amide inhibits the activity of dissected pharyngeal myogenic muscle system.
What are the official names of this protein?
FMRFamide-like neuropeptides 19.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_DESVH
Sequence: MKRTYQPSKIRRKRSLGFRARMATAAGREIIRRRRAKGRKKLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: Y2624_BACCR
Sequence: MNKLSTKLVVAIGIGAALYGILGLWGFSIAPNTFIKPALAILTVFGALFGPVAGLLIGLIGHTVTDTIAGWGIWWGCYPTLLNCPLH
What are the official names of this protein?
Putative UPF0397 protein BC_2624.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AP24_ORYSJ
Sequence: MAATFYGVGSIALAMHEDDEEEGSGRVFGFAAGDLVRPAVVTQQLFPMTAAAAAVVPESTEQRHVAAAAEQWARPPSRKTRRGPRSRSSQYRGVTFYRRTGRWESHIWDCGKQVYLGGFDTAQAAARAYDQAAIKFRGVEADINFTLDDYKEDIKKMNNFSKEEFVQVLRRQGAGFVRGSSRFRGVTLHKCGKWEARIGQLMGKKYVYLGLYDTEMEAAKAYDKAAIKCCGKEAVTNFDTQAYEDELNLQSWDSELDLELSLGCSGGERAAGEVLHSAPSNQRTSLTFMLPEEEEMTACHRQRSIWARPSLAPAMPDGGAVIRPDQHQHHPSSRNMLLMSQVISSSGGGGGSGRQGAAELHMRPRHGWSSGGNNWAPPYAARPRLPGAEDDEDDDSAAAASSGFPMGQVATASSPSRPSSSSCSSRRSSTAAATATTGR
What is the function of this protein?
Probable transcription factor (By similarity).  Involved in spikelet transition (Probable).  Prevents lemma and palea elongation as well as grain growth (PubMed:28066457).
What are the official names of this protein?
APETALA2-like protein 4, Protein GLOSSY 15, OsGL15.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. AP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MEND_GEOTN
Sequence: MTNALSWYVAAFVDGLVQAGVTEAVISPGSRSTPLAMAMAAHSGLHFSMHIDERSAAFFALGMVKAKQRPVALVCTSGTAAANYLPAIVEAYYSRVPLVVLTADRPHELRDVGAPQAIDQLHLYGRYAKWFVDLALPEETDPMLSYARTMAARAAAIAAGAPAGPVHVNVPLREPLVPTIDEAVWEKVRTVAETPQIMSGRATLPAENVAALYEQLAAAKRGLIVCGALDQPGFAEAVTELARTLDFPILADPLSQLRAGAHDKTYVIDSYDAILKDEAVASRLVPDVVLRFGAMPVSKPLFLWLKQHRSIRQIVVDDGGWRDPTLEAACFVRSDETVLCRQLLDIARPKQKESAWSTTWREMNDIARTVLRQHLPADEWFEGKVFTELAELLPAGATLFVGNSMPIRDADTFLFATDKPLRVLANRGANGIDGVVSSALGASLAASPLVLVIGDLSFYHDLNGLLAAKMHGLQATIVLMNNNGGGIFSFLPQARHEGPFETLFGTPTDLTFAHAVEMYGGRYAVPHTWGEFRHHVAESLNTGGLSVIEVRTSRTENVQMHRFLWERVSQEIAKFLEQKGTEEPWN
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: Y1145_VIBCH
Sequence: MNIDVVLLLEQNPILLIFVVLAIGLSFGKIRFGSFQLGNSIGVLITSLIMGHLGFSFTPEALTIGFMLFIYCVGIEAGPNFFGIFFRDGKHYLILSLVVLITATWIAYFGGYYLNLDYGLAAGMMAGALTSTPVLVGAQDALNSGLAAVPRHMDLSLILDNVSVGYAMAYLIGLISMIMFAKLLPKLQKQNLSDSAQQIAQERGLGSQRKVYLPIIRAYRVGPELINWIDGRNLRELGIYRQTGCYIERIRRHGILAHPDGDAILQEGDEIALVGFPDSHARLDPSFRNGKEVFDRNLLDLRISEEEIVVKSDSIAGKRLSDLNLSEYGCFLNRVVRAQIEMPMDLDIVLAKGDVLQVSGEKSKVKGLADKIGFISVHSQMADLLAFCSFFILGILFGLVTMTFGQVSFSLGNAVGLLLSGITLGFLRANHPTFGYVPQGALNMVKDLGLAIFMVGIGLNAGSKMFQHLSEVGVQVIGLAFLVSVVPVVFAYLVGAYILKMNRALLFGAIIGARTCAPAMDVVNEYAKSTIPALGYAGTYAIANILMTLTGTIFILLS
What are the official names of this protein?
Putative transport protein VC_1145.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y041_SYNY3
Sequence: MTQNPSSDRRPDTAQSVANGETLDGALFTGLTDTAAAQDESSETSASFATIDGEDKSEVGDALDWFSDGKETDINGDEADRGIQADTQAKTLVSLENLTEEPEIDGAEFMAEAFIAENTAVEDVSPNPNPAIDTDALAALTQSAVELTPPPPINLPKVELPPMQPLAPLMAIADPDNLSPMSTSIQAPTQSGGLSLRNKAVLIALLIGLIPAGVIGGLNLSSVDRLPVPQTEQQVKDSTTKQIRDQILIGLLVTAVGAAFVAYWMVGENTKAQTALALKAKHSHRNLDQPLAVAGDELAIADQTIDALSAQVEKLRHQQDLSLKQAELLTELSRANLSDIDEIQGVIQKNLDQARALFGCERLVFYYHPRYQPEAMVVQALDLTTQGLIDSKDPHPWGQEDMPSQIVAINDTSGASISNPHRQWLEQHQVKASLTVPLHRDNYPLGLLMAHHCQRPHQWEMRERQFLQQLTEELQTTLDRANLIQERNESAQQAQILKELTLKISAAINSEQVFDIAAQEIRLALKADRVIVYRFDATWAGTVIVESVAEGYPKALGATIADPCFADSYVEKYRSGRIQATRDIYNAGLTPCHIGQLKPFEVKANLVAPINYKGNLLGLLIAHQCSGPRDWHQNEIDLFGQLTVQVGLALERSDLLAQQKIAEVEQRQMREKMQKRALELLMEVDPVSRGDLTIRAHVTEDEIGTIADSYNATIESLRRIVTQVQTAASQFTETTDTNEVAVRQLAQQANRQALDVAEALERLQAMNKSIQAVAENAAQAESAVQRATQTVDQGEDAMNRTVDGIVAIRETVAATAKQVKRLGESSQKISKVVNLIGSFADQTNLLALNAAIEAAHAGEEGRGFAVVADEVRSLARQSAEATAEIAQLVATIQAETNEVVNAMEAGTEQVVVGTKLVEETRRSLNQITAVSAQISGLVEAITSAAIEQSQTSESVTQTMALVAQIADKNSSEASGVSATFKELLAVAQSLQEAVKQFKVQ
What are the official names of this protein?
Putative methyl-accepting chemotaxis protein sll0041.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
Protein: EST5B_DROMI
Sequence: MYCEKLILLLGCFWISSSASDPADPLLVDLPNGKLRGRDNGNYYSYESLPYAEPPVGDLRFEAPQPYKQQWTDTFDATQPPVLCMQWDQFIQGDDKLAGNEDCLTVSVYRPKNSSRNSFPVVAQIHGVAFMFGGASQNGHENFMREGNLILVKISYRLGPLGFVSTGDADLSGNFGLKDQRLALLWIKQNIASFGGEPENILVIGHSAGGGSVHLQVLREDFSKVAKAAISFSGNALDPWVVQQGGRGRAFELGRIVGCGQASDSVTLKKCLKSKPASEIVSAVRNFLVFAYVPFTPFGPVVESPEAPEAFISQHPIDIIKSGKFAQVPWAVTYTTEDGGYNAALLLEKQASSGRELIVDLNDRWFDWAPYLLFYRDSMTTIKDMDDYSRKLRQEYLGDRRFSVESYWDLQRLFTDVLFKNSTEISLDLHRKHGKSPVYAFVYDNPANTGIGQGLAKRTDINFGTVHGDDYFLIFENIVREPQLRSDEEIISRNFLKMLNDFVLSENGTLAFGTCDFQDNVGSSKLQLLSITRNGCENLELESFP
What are the official names of this protein?
Esterase-5B, Est-5B, Carboxylic-ester hydrolase 5B, Carboxylesterase-5B.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CALR_CHLRE
Sequence: MKWGVVAVLATLVVAASAKDYFKETFDGSWADRWTKSSWKVSDGSAGEFKLTAGKWYGDAEADKGIQTGPDSKFFAISAPLATVFDNTGKDTVVQFSVKHEQDLDCGGGYIKVVPATSEKQMGEFGGDTPYSIMFGPDICGYSTRKVHVILTYKGKNYLIKKDIKAETDQLTHVYTLVIKPDNTYQVLIDLKEVASGSLYEDWDMLPPKTIKDPKASKPEDWDEREEIADPEDKKPEGWDDIPATIADKDAKKPEDWDDEEDGTWEPPMIPNPEYKGEWKAKMIKNPAYKGIWVAPDIDNPDYVHDDKLYNFKDLKFVGFELWQVKSGSIFDNILVTDDLEAAKKFAEDTWGKHKDEEKAMFDKVKKEEDEKKAKDAPPPPVDAEAAEEEDDEYEDKEEPSGMGSIKIPKEEEESGHDEL
What is the function of this protein?
Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle.  This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity).
What are the official names of this protein?
Calreticulin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: TOP1_MYCGA
Sequence: MTNHSSKILVIESPNKVKTIKKYLTDDYEIVATVGHIRDLPKYTLGFNTEDFVPKWEIIQEKKPAKGVSATKKAKTVKKAVKNKKEIIDELVDKAKKADEIYLATDPDREGEAISWHVYDVLKEKGVNVNKCKRIIFNEISEKAVKNAIANPREIQKDWVSSQITRRRLDRLIGFKLSSLMKSKINADSAGRVQSIALKFITEREELINKFVPRFWWTLDVILKDGTELMLRKIDEKLKDKLGFKELEEVSGIDFNTKEDAELVKQHLSDKYRVYAIDTPKLKSSYPKEVYKTSTLQQDAINKLKWRSMKITSVAQELYEGVTIDDEQIALISYPRTDSTRLSPEYGKTVLDFVAKTYGKDYVATQSQLNGETKANKKQKAKVQDAHEAIHPIDISITPDSVKNKISSDQYSLYKLIWTRTVAHYMAAAVYELVNIRFINNNNKFYAVNNTLKFDGYKKIYTHYDDKDHLRKLDLNHFAIDKEFEAKDVLLNEHQTKPPARFTQATLIEALETEGIGRPSTYSTILDIVLKRNYAELVNGRYYKTTDLGQKLAFELDKNFPTIINKEFTKNMETTLDEIAQGTVNDVSYLQAFWNDFSEVLNEAKTNIVKKVEYIEGKNCPNCSSQLVRREGRYGPFVGCSNFPKCKFIEKSEQKAKEIVYEEGVKCELCHAKLIRRVAKKKGRNKDNTFLGCSNFPKCKYTKSLEPEKDETIRDSTII
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.