PharMolix/UniProtQA huggingface dataset:
Protein: BGAL1_BACSU
Sequence: MRKLYHGACYYPELWDEETIQQDIDIMREVGVNVVRIGEFAWSVMEPEEGKIDVGFFKEIIARLYDSGIETIMCTPTPTPPIWFSHGRPERMHANEKREIMGHGSRQHACTNNPYFRKKAAIITTAIAKELGRLPGLIGWQLDNEFKCHVAECMCETCLRLWHDWLKNRYGVIERLNEAWGTDVWSETYQTFEQVPQPGPAPFLHHASLRTMYQLFSMEMIASFADEQAKIIRCYSDAPITHNGSVMFSVDNERMFQNLDFASYDTYASQENASAFLLNCDLWRNLKQGRPFWILETSPSYAASLESSAYPHADGYLQAEAVSSYALGSQGFCYWLWRQQRSGSEISHGSVLSAWGEPTIGYQNVLAVERARKEIEPIILSTEPVQAEAAMTYSDRAKAFIKTEPHRGLRHRSLVTHFYERILNTGIHRDLIPEGAPLDGYRLLFTPFVPYLSSEFIKKASAFAEAGGIWITGPLTGGRTCEHTIHTDCGLGELEKTSGIKTLFTFPMNENVNTGKAFGITAPLGLWSAVFDTESGNTLGTVEAGPGAGHAFLTERNYGEGKIVMLGSLPSGKEGDAMLEALVRHYAEEAVISSRSDVTPGTIVAPRIGENGLVWIVVNMDGKGGSVTLPESGTDLLTHRLEKAGRLAVGPHEYRVIQFDNHS
What is the function of this protein?
May play a role in the degradation of rhamnogalacturonan derived from plant cell walls.
What are the official names of this protein?
Beta-galactosidase YesZ, Beta-gal, Probable rhamnogalacturonan beta-galactosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 42 family.
Protein: FOLD_CAUVN
Sequence: MAQAKLIDGKAFAADLRAKIAEEVAALKAEHGVTPGLAVVLVGEDPASQVYVRNKGEQTTAAGMYSETHRLPETTTQDELLAVVAKLNADPKIHGVLVQFPVPPHISQMDVVAALSPDKDVDGLTVTNAGRLASGLPALAPCTPTGCMMLIRDAIGDLKGKTAVVIGRSNLMGKPMAQMLLAADCTVTIAHSRSQDLPSIVRQADIVVAAVGRAEMVKADWVKPGAVVIDVGITRFPARDPEAAAAGKTRLVGDVAFDEVREVAGAITPVPGGVGPMTIACLLANTLTAAKRLSGIA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: Y2592_STRCO
Sequence: MKITFLLTWGDEMGGTEQAVYTQATHLAPRHDIEVLSVFKTREQPFFSVDERVSVRYLVDRTGKTERPVRESDLTAEDCRHLAGLPSDLISPKWEATFDALSDVEMQRALRTIDTDVLITTSPALMSAVADLAPSRVITIQQEHRPSQLRGGTGEPLLLRAPAIDALVVLTERTKQWLEESLGKAAPRLAAIPNAIPEGFRPRSSLTGKTIVMPRRLVPDKQVDHAIQAFAKALPDHPGWRLRIFGDGPQMSRLRNLIQGLGLHDSVELLGPSQHMTEEWARASLTILPSQDGEAFPLVLLEAFAAGVPAVAYDIVTGPAEIIRHGEDGLLVPPNDVESLAEAISRLMGDEALLRSYGEKAHEGSTRFAADVIVKQWEELFTELVSRRDDPRRMAERADRIAHRVAHGGAGRFHAAVAADRTAPSSGDQRAREVVIGASDRSLVRAGGRLSEVRDDLQGSEIVQRNFETVVEALESSGIPYVLLRDRDDNPRRRLAVDAAEQTRVRKALAGAYEGKAVYAELLKPRTHAPGVLLAERLEAVGEVAGLRVFRPVVTSTRTLRFGPAYGCDIEFWRQVPEEEGGDGQFVAPLRPSAVGPKLPSLTPDARTRVKDREYPTLEPLTRKLVSDITFPVDAVYTWVDDSDPRWQERRARRRAALGLEAESSGDEAARFRNRDELRYSLRSLAMFAPWIRKIYLVTDDQTPEWLNTEHEGIEVVSHRDIFTDQDCLPTFNSHSIESQLHHIDGLSEQFLYLNDDVFIGRPVGAQRFFLPNGASRFFWSPTTVPVGEPTEEDEGYFAAAKNNRALLEERFGVTVANSFVHAPHPLRRSVLESIEEDFPESVARTAATPMRGWQDISMVSSLHHHYGYLTGASVPSSIRCAYIDVGTYSRHPELTRLLAMRGHDVFCLGESQDAEVPEHEQARIVEAFLRAYFPVKSPYER
What are the official names of this protein?
Exopolysaccharide phosphotransferase SCO2592, Stealth protein SCO2592.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: TBL26_ARATH
Sequence: MEQQLTLVLLDSPKGAKYVETFEEAASSSSSSSSSSVPSCTDHRHRTFVKFFLYFSLVALAYYFIISSLAVSPIPPTLPQSSPGNVSSAKCDLFTGDWIPDPTGPLYTNVTCRHIQDFQNCLLNGRPDVNYLFWRWKPRDCDLPRFSPSQFLASVKNKWWAFIGDSIARNHVQSLICILSQVEEVEEIYHDKEFRSKIWRFPSHNFTLSVIWSPFLLKSETSSNSDIQLYLDQLDHKWTVQYPKFDYVVISGGKWFLKTTIFHENNVVTGCHYCQGRNNLTDLGYDYSYRKTLNLLRDFVLNSTHKPLVLFRTTTPDHFENGEWNTGGYCNRTMPFKEGQANMKTVDDVMRDVELEVFQKFGKGFGLGSNIRLLDTTGMSLLRPDGHPGPYRHPNPFAGVKNKSNVQNDCLHWCLPGPIDSWNDVMVETTLNRERELYDLTG
What is the function of this protein?
May be involved in the O-acetylation of mannan (PubMed:22086088).  May act as a bridging protein that binds pectin and other cell wall polysaccharides.  Probably involved in maintaining esterification of pectins (By similarity).
What are the official names of this protein?
Protein trichome birefringence-like 26.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL9_PROM1
Sequence: MAKRVQVVLNEDIKSLGNDGDLVEVAPGFARNFLLPNKKALPVTPTVLKQVEHRRAKQAEKEAAKKQEAIDFQTALTTIGRFTVKKQVGEDGVLFGTVTNGDVAEVVKEATKKDIDRRDISVPEIHGVGKYKVQIKLHNEVNAEINLEVTSY
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: VATE_METMA
Sequence: MGLEIVVKDIQEGARAEVSRIKAEGDAKASEIINEAKEIQKKTLGDSLAKAEEDLQSLHQQVISSANLEVKRITLNKRKELLDTVYNQTVENIKSMPASKKEELLKSILDKHEASGARAYSSKESEELVKKLTSLSYAGNIDSIGGIVLENEDRTVRLDFTYDSILKSVYERSLKQISDILYG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: LEPA_ACIAC
Sequence: MNHIRNFSIIAHIDHGKSTLADRLIQRCGGLEERQMEAQVLDSMDIEKERGITIKAQTAALQYKARDGQVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTALDLGVEVLPVLNKMDLPQADPDNAKAEIEDVIGIDATDAIPCSAKTGMGIDEILELIVAKVPAPRGNPDAPLRAMIIDSWFDPYVGVVMLVRVVDGRLLKGERFKMMASGAAYNADNLGVFTPANEPRNALNAGEVGYIIAGIKELKAAKVGDTITLEKKLPNNLGPAEQALPGFKEIQPQVFAGLYPTEASEYDQLRDALEKLQLNDASLHFEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDQDLITTAPSVVYEVVKGDGEVIMVENPSKMPDQGRIQEIREPIVTVHLYMPQEYVGPVMTLANQKRGVQLNMAYHGRQVMLTYELPLGEIVLDFFDKLKSVSRGYASMDYEFKEYRASDVVKVDILLNGEKVDALSIIVHRSQSAYRGRAVAAKMREIISRQMFDVAIQAAIGANIIARETIKALRKNVLAKCYGGDITRKRKLLEKQKAGKKRMKQIGSVEVPQEAFLAILQVEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YSD2_CAEEL
Sequence: MPMLPPVANALKRSETGAEETSEQDAVKRTKVLDMAQKVTRQIISSANAPGAIGPYSQAVRAGNTIYLSGSLGLDPKTGDLKEGVVEQTHQSLKNLGEVLKAAGADYGNVVKTTVLLQNIADFAAVNEVYGQYFKSPYPARAAYQVAALPKGGLVEIEAVAIAGEIEEVKN
What are the official names of this protein?
RutC family protein C23G10.2.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: RF1_METSB
Sequence: MLPQEKLDLILRRYDEVSARLNEAVEPALYVQLSREFAGLEQVAAAIRDYRSQMQEVEGLAAMLADPTTDSEMRGLAEEELRDAKERLEALEHQLKIALLPKDAADERSAILEVRAGTGGDEAALFAGDLFRMYQRYAESKGWSVEIISANEGAAGGFKEIIAEIAGRGVFAKLKFESGAHRVQRVPDTETQGRIHTSAATVAVLPEAQEVDVEINEADLKIDTMRAQGAGGQHVNKTESAIRITHIPTGTIVFVQDERSQHKNRARAMALLRSRIYDEQRQKLDAERAADRRSQVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDKVITGEALDEVIDALTTHHQAALLADSESGGL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSL3_ARATH
Sequence: MDLDSSMVPENDQDPIATSENQSPMEEKEEASEQQTGSESESASLTPSLPPPSQQQQQQQQQPQVTAVVGPRCAPTYSVVNAIIEKKEDGPGPRCGHTLTAVPAVGEEGTSSYIGPRLILFGGATALEGNSGGTGTPTSAGSAGIRLAGATADVHCYDVLSNKWSRLTPYGEPPSPRAAHVATAVGTMVVIQGGIGPAGLSAEDLHVLDLTQQRPRWHRVVVQGPGPGPRYGHVMALVGQRYLMAIGGNDGKRPLADVWALDTAAKPYEWRKLEPEGEGPPPCMYATASARSDGLLLLCGGRDANSVPLASAYGLAKHRDGRWEWAIAPGVSPSARYQHAAVFVNARLHVSGGALGGGRMVEDSSSVAVLDTAAGVWCDTKSVVTSPRTGRYSADAAGGDASVELTRRCRHAAAAVGDLIFIYGGLRGGVLLDDLLVAEDLAAAETTSAASHAAAAAAATNTPPGRSPGRYGFSDERTGELPESAPDAVVLGSPVAPPVNGDMYTDISTENAMVPGIRRTSKGVEYLVEASAAEAEAISATLAAAKARQVNGEVELPDRDRGAEATPSGKPSLSLIKPDSAVPNSVIPAGVRLHHRAVVVAAETGGALGGMVRQLSIDQFENEGRRVSYGTPESATAARKLLDRQMSINSVPKKVVAHLLKPRGWKPPVRRQFFLDCNEIADLCDSAERIFSSEPTVLQLKAPIKIFGDLHGQFGDLMRLFDEYGSPSTAGDISYIDYLFLGDYVDRGQHSLETITLLLALKVEYQHNVHLIRGNHEAADINALFGFRIECIERMGERDGIWVWHRINRLFNWLPLAALIEKKIICMHGGIGRSINHVEQIENIQRPITMEAGSIVLMDLLWSDPTENDSVEGLRPNARGPGLVTFGPDRVMEFCNNNDLQLIVRAHECVMDGFERFAQGHLITLFSATNYCGTANNAGAILVLGRDLVVVPKLIHPLPPAITSPETSPERHIEDTWMQELNVNRPPTPTRGRPQNPNDRGSLAWI
What is the function of this protein?
Phosphatase involved in elongation process, probably by acting as a regulator of brassinolide signaling.
What are the official names of this protein?
Serine/threonine-protein phosphatase BSL3, BSU1-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. BSU subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PNP_ALIFM
Sequence: MFANPVVKSFQYGNHTVTLETGVIARQATAAVMASMDDTSVFVSVVAKKEAVPGQDFFPLTVNYQERTYAAGKIPGGFFKREGRPSEAETLTARLIDRPIRPLFPDAFKNEVQVIATVVSINPEVNPDMITMIGTSAALAIAGIPFNGPIGAARVGHINGELVLNPSNTELENSKLDLVVSGTEGAVLMVESEADNLTEEEMLSAVVFGHDQQQVVIKAINEFAAEVATPAWDWVAPEENTVLNSRIAELAEAKLVEAYQITEKMTRYDRIHEIAAEVNEVLVSENEDVNLKEVHTIFHDLEKTVVRRSIIAGNPRIDGREKDMVRALDVRTGVLPRTHGSSLFTRGETQALVTATLGTQRDAQIIDSLMGEKKDHFLLHYNFPPYCVGETGFVGSPKRREIGHGKLAKRGIQAVMPSIEEFPYTVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKASVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTNEGITALQMDIKIEGITKEIMQIALNQAQGARKHILKVMDEAISGAREDISEFAPRIHTMKISSDKIKDVIGKGGAVIRALCEETGTTIEIEDDGTIKIAATEGAAAKEAIRRIEEITAEVEVGKIYTGKVMRIVDFGAFVTVLGPKEGLVHISQIAEERIEKVADHLQVGQEVKTKVLEIDRQGRIRLSIKEANAELNPAPAAEAKDAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOD1_XENLA
Sequence: MAESGSGTSGGSSSVGGVSNPASLAPGDSQLIALIVEQLKSRGQFDGFRRDCLADVDTKPAYQNLRQKVDNFVSTHLDKQEWNADMNKNQLRNGLRQSVIQSGMLEAGVDRIISQVVDPKLNHIFRPQIEKAIHEYLTAQTKEDSAPPLPPGPPEPQEQEPPEPSQSVS
What is the function of this protein?
Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.
What are the official names of this protein?
Biorientation of chromosomes in cell division protein 1, Biorientation defective protein 1, Protein FAM44B.
What is the protein family that this protein belongs to?
Belongs to the BOD1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Note=Localizes at the centrosomes throughout the cell cycle, only dissociating during cytokinesis. Localizes at the kinetochore from prometaphase until anaphase.
Protein: 5HT2B_TETFL
Sequence: MFQAAVGPLQTNISLPEETPGLELNWAALLIVMVIIPTIGGNILVILAVWLEKKLQNATNFFLMSLAVADLLVGLLVMPIALITILYDSDWPLPEPLCPIWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQHSQYKSRAKVMLKIALVWLISICIAIPIPIKGLRNYPHPNNITFTSNHTCVLKTDTFQEFIIFGSLVAFFIPLTIMMIIYFLTVRVLRKKVYLLRSKVTQRFSYPIISTVFQREQAANPPQPEQPDSTGNSLARIQEKTDTDGMSSPTGDEKSFRRLSTMGKKSMQTLTNEQRASKVLGIVFLLFVVMWCPFFITNITSALCGPCDANIIGRLMEIFSWVGYVSSGINPLVYTLFNKTFRQAFTRYITCNYRNFASKEQGRSFRASTVDRMLTHISPRSSVAENAKLFTKQEIKNETTDYRSPLGCLQPSAQTSTGVVLDKILLTHTENCKQEERVSCV
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.  Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores.  Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity (By similarity).
What are the official names of this protein?
5-hydroxytryptamine receptor 2B, 5-HT-2B, 5-HT2B, Serotonin receptor 2B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: YBEY_FUSNN
Sequence: MELIVDFSSDLQTEKYNMFIDTLYENNHLENYIKKVLNLEKIESDRPLYLSLLLTDNENIQVINREYRDKDAPTDVISFAYHETEDFNIGSYDTLGDIIISLERVEEQASEYNHSFEREFYYVLTHGILHILGYDHIEEEDKKLMREREEAILSSFGYTRDK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PT127_SCHPO
Sequence: MLIYKKKNFGRRSVYNLKKCLHKGFQINSCNIKAADNVLHSKASAFEKVNVVDKESIGNLQHHLDTVLPKKKFQFLRDPKTNDYKWDEYLSKILPVDKFNFGLLSKFRPPSEDEQLQKVANSIGAEFVGSTSSLTGLMSQLHFFISKWKFPNFSDLSKGFYISPNERNFTRLCRSASSVHISYQNGLYCIDKDKSLTKEPSVNIILMNVGKSLETFFTVDKDQFLLYKKPPSSNGVLKPLKDVFQYGRCSSLLVRSQLDCYDKKIPESGVFDLKTRAVFGVRMNQTQPELFKSYKLTHYYGNRISFEREYFDLIRSAFMKYSLQARLGYMQGVFVAYHNTSDIFGFQYIPLVAMDRAIHGSSEIGEAEFNLNLQLLEKILQYATSIFPKRSFRVMLSTTEDVPNPPLKVYLEVADDKENRGFDLLDGQKNLEAKTVSPSNFCALEVCALQFVNGVHKSVVKHLDEKETWSIKYHFRKPRDQDNLLRNYIRLRDDIKRRESKISNPPESLLHDYYACSEQYYKRN
What is the function of this protein?
Required for the degradation of mRNA in mitochondria.
What are the official names of this protein?
mRNA degradation protein pet127, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PET127 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NUOK1_SYMTH
Sequence: MPAFSLNAYVALSAVLFALGGIGVLVRRSPLAILMCIELMLNAANLLFVAFGRAHGGYEGQIMAFLVITVAAAEVAIGLALTVLLFRRRAEVDVDRVNELKL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 1, NADH dehydrogenase I subunit K 1, NDH-1 subunit K 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTRY_AZOBR
Sequence: MSPTPPETVTPLWQQFLRWAARVGLAKRLAFALSLAALVAGFATYTALTESAPFGETNPRTVTWLLTLDLALLLLLGVLIARRIVYLWIGRRRGLAGSQMHVRLVAVFSLLAVAPAIIMAIFSTVFFYVGVQSWFSERVRTAVNESLAVASAYLHEHQQNIRADALAMANDLNQEAARLASDPERFEQVVATQAMLRALSEAIVFNGTTGAIVARSGYTFALEFDPIPDDKLATARRGEVAMIVSENDDRVRALVRLDRFADTYLYVGRMVEPRVLSHMASAEGAVREFGALESQRGSLQITFTLIFLCVALLLLLAAVWAGLIFATRLVRPISALIGAADRVRAGDLTVRVTERPAEDDLALLSRAFNRMTTEIESQRHALLSANRLIDSRRRFTETVLSGVSAGRDGLDAEGRITLSKFSAARLLGVKDAESLIGMRLAELVPEMGGLLHEAPGRPGLVVQDQIKIRRDGTTPLTLLVRISTEGRGSGMMRGYVVTFDEHHRTWSPAQRKAAWARRRPIAASPTRVKNPLTPIQLSAEPCAASTLKEITSDTEVFTMCTDTIVRQVDDIRRMVDEFSAFARMPQPVMKPCNLNDLVRQAVFLQSSAHAGKIKFDMALPQGPLTVPCDSRQISQALTNLLQNAADAIEGRPPPAEGTELPPGHVAIRVEADAERIAMIIEDNGKGLPTEERDRLTEPYVTTRAKGTGLGLAIVKKIMEDHGGVLTLEDREGGGARVGLVIPQHIPPASGTAAGDAPGGVGTPAETGEEKRHAAHGA
What is the function of this protein?
Member of the two-component regulatory system NtrY/NtrX involved in nitrogen level control.  Probably activates NtrX by phosphorylation (By similarity).
What are the official names of this protein?
Nitrogen regulation protein NtrY homolog.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BTUD_ECOUT
Sequence: MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPANLAQAYGMNFRRLDIEGHRMLISTI
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEUC_MYCPA
Sequence: MGIDTGTTATPRTLAEKVWDDHVVVSGGANEPDLIYIDLHLVHEVTSPQAFDGLRLAGRPVRRPDLTLATEDHNVPTVDIDKPIADPVSRTQVETLRRNCAEFGVRLYPMGDAEQGIVHVVGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGELPAGVTAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTVCNMSIEAGARAGMIAPDDTTYEFLRDRPHAPKGAQWDAAMRYWQQLRTDPGAVFDTEVYLDAASLSPFVTWGTNPGQGVPLAAAVPDPELMTDDAERQAAEKALAYMDLRPGTPMRDIAVDAVFVGSCTNGRIEDLRVVADVLRGRKVAPGVRMLVVPGSMRVRAQAEAEGLGEVFTAAGAEWRQAGCSMCLGMNPDQLAPGERCAATSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSAPADLD
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: VPS27_MAGO7
Sequence: MMSWWSSGANTALDEQIEKATSSSLEDIALNLEISDVIRSKTVPPKDAMRSLKKRIGHKNPNTQLSALELTDTCVKNGGQHFLVEIASREFIDNLVSLLKATGPAAVNADVRARILGLIQSWAAVTQGRVELSYIGEVYKTLQHEGFQFPPKVAVATSMIDSSAPPEWTDSDVCMRCRTPFTFTNRKHHCRNCGSCFDQQCSSKSIPLPHLGIMQPVRVDDGCYAKVTDKSRGSGGAGAGAGYDRKSPSLYSSFPHKNRSSSAMQPRSARVDDGFDEDLKKALAMSLEEVKSHSRNYAPASNGVANSGQSKVNGDSSATKTVEEEDDDLKAAIAASLADMEEQKKKHSAVLHEQTHSTEAASASTFVPPKNDYELTPVEAENINLFATLVDRLQTQPPGTILREPQIQELYDSIGTLRPKLARTYGETMSKHDTLLDLHAKLATVVRYYDRMLEERLSKAYGQRNFAGYNMHVPRQTSSPYPSLQGPSAPANVPGESFYTGQPQHDYAEPSRQPSYPPQASGAQQQFHQYAPPHQASQPSEGWQPSHTPAPAAQYAGQPPQQSTESTHSHSSAHNHQNLAAPSAPDQSLPTPTTDPAASYYFNQQQVSALQTPVSVPAEPVQSPYPNLQQQPPAQYQHSPAPQGQAQQQKPPQQPQQPYWQHSASQNTALPTNHQPWPQVPNRQSASYVQEPLPSAPQHAPQKPVVEEALIEL
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 27.
What is the protein family that this protein belongs to?
Belongs to the VPS27 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PANB_PSELT
Sequence: MNVNKFKSMKGKKPIVMLTAYDSVFASIVHQAGVDAILVGDSLANNVLGYSDTLPATMEDMIRHTQAVRRGAPEAFIIADMPFLSYQCSSDEAVRNAGRFLKEAGANAVKLEGGSFFSTTIERIVKSGIPVMGHLGLTPQSVNVFGGYKVQGKGDKSAKYLLEEAKALEEAGVFSIVLEMVVEETAKMITENLSIPTIGIGSGRFCDGQILVINDLLGMNPSFLPKFAKRYSNLFQISLEAVKNYVSDVQNHRFPFEENVFKAGE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1A_CYLCV
Sequence: MSQERVDKLRKLRIEFEGIIQRMEVAKNLLRELEETTDRVRVDRLQMEVGFLRDYADINCMIEKDRIKEQSSSSSATRTTQEPSLHLPD
What are the official names of this protein?
Uncharacterized protein 1a.
Protein: RL22_SALHS
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ILVC_RHILO
Sequence: MRVYYDRDADLNLIKGKKVAIIGYGSQGRAHALNLKDSGAKEIAIGLKAGSATAKKVEADGLKVMSVADAAKWADLMMMATPDELQADIYKNEIAPNIRDGAAIAFAHGLNVHFGLIEPKSTVDVVMIAPKGPGHTVRGEYQKGGGVPCLVAVNQDASGNALDLALSYACGVGGGRSGIIETNFREECETDLFGEQVVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEWGEYVSGPRIITAETKAEMKRVLKDIQTGKFTSEWMQEYRAGLSRFKGIRRMNDSHQIEEVGAKLRAMMPWISKNKLVDKAKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LOXL3_HUMAN
Sequence: MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQII
What is the function of this protein?
Shows protein-lysine 6-oxidase activity toward elastin and different types of collagens, with the highest activity toward collagen type IV (PubMed:17018530).
What are the official names of this protein?
Lysyl oxidase homolog 3, Lysyl oxidase-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the lysyl oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Cytoplasm. Nucleus. Note=It is unclear how LOXL3 is both intracellular (cytoplasmic and nuclear) and extracellular: it contains a clear signal sequence and is predicted to localize in the extracellular medium. However, the intracellular location is clearly reported and at least another protein of the family (LOXL2) also has intracellular and extracellular localization despite the presence of a signal sequence (PubMed:28065600). SUBCELLULAR LOCATION: [Isoform 1]: Secreted, extracellular space. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Secreted, extracellular space.