PharMolix/UniProtQA huggingface dataset:
Protein: TNAA_ECO27
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: GRP75_PONAB
Sequence: MISASRAVAARLVGAAASRGPTAARYQDGWNGLSHEAFRIVSRRDYASEAIKGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLSRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEKQ
What is the function of this protein?
Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis.  Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU.  Regulates erythropoiesis via stabilization of ISC assembly.  May play a role in the control of cell proliferation and cellular aging.
What are the official names of this protein?
Stress-70 protein, mitochondrial, 75 kDa glucose-regulated protein, GRP-75, Heat shock 70 kDa protein 9.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus, nucleolus.
Protein: AZUP_METEA
Sequence: MMIFRALIAAATLAIAIATTLPAAADEVAVKMLNSGPGGMMVFDPALVRLKPGDSIKFLPTDKGHNVETIKGMAPDGADYVKTTVGQEAVVKFDKEGVYGFKCAPHYMMGMVALVVVGDKRDNLEAAKSVQHNKLTQKRLDPLFAQIQ
What are the official names of this protein?
Pseudoazurin.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYI1_BACAN
Sequence: MEYKNTLLMPKTEFPMRGNLPKREPAMQEKWAEMNIYETVQEHTKGRPLFVLHDGPPYANGDIHMGHALNKVLKDFIVRYKSMTGFCAPYVPGWDTHGLPIEQALTNKGVKRKEMTVAEFRKLCAEYAYEQVERQREQFKRLGVRADWDNPYITLEPAYEAQQIKVFGDMAKKGYIYKGQKPVYWSPTSESALAEAEIEYQDKKSASIYVAFSVKDGKNVLEGDEKYIIWTTTPWTLPANLGISVHPELEYAIVKVNDEKYIIASELFETVAKTLEWENAEVVKTVKGSELEYTVAKHPFYDRDSLVMLGDHVTTDAGTGCVHTAPGHGEDDFIVGKKYGLEVLCPVDDKGVLTEEAPGFEGLFYDKANKPITEKLEEVGALLKLTFITHSYPHDWRTKKPIIFRATAQWFASIEAFRKELLEAVAETKWVPAWGETRLHNMVRDRGDWCISRQRAWGVPIPVFYAENGDPIITDETINHVADLFREHGSNVWFEREAKDLLPEGFTHPGSPNGEFRKETDIMDVWFDSGSSHQAVLEERDDLQRPADLYLEGSDQYRGWFNSSLSTAVAVTGKAPYKGVLSHGFVLDGEGRKMSKSIGNIVVPKKIMDQLGGDILRLWVSSVDYQSDVRISDDILKQVAEVYRKIRNTFRFLLGNLDDFKPSENTVAVAELREVDRYMLVKLNDLITKVKEAYETYDFAAVYHAIHNFCTIDLSSFYLDFAKDILYIEGANHEDRRAIQTVLYDVLVALTKLVTPILPHTADEVWPYIPGVTEESVQLTDMPEAVQLDDAEALKTKWDAFMTLRDDVLKALEVARNEKVIGKSLNASITLYPTAEMKAMLESINEDLKQLFIVSEYKLGGMMEEAPADAPKYEHTAVVVAQATGETCERCWVVSETIGKDAEHETLCERCATVVKENYVK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase 1, Isoleucyl-tRNA synthetase 1, IleRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_CAMJD
Sequence: MSKEKEVLLNEEIRADEIRCVGDDGKVYGIISSDEALEIANRLGLDLVMIAADAKPPVCKIMDYGKFRYQQEKKQKEAKKKQKVIDIKEIKLSVKIAQNDINYKVKHALEFLEQGKHVRFRVFLKGREMATPEAGVVLLEKIWTMIENEANRDKEPNFEGRYVNMLVTPKKA
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_BRUSI
Sequence: MKINGNEIRPGNVIEHEGGLWVAVKTNAVKPGKGGAYNQVELKNLINGTKLNERFRAAETVERVRLEQKDFSFLYEQGEALIFMDTETYEQLELQKDFVGDRAAFLQDGMMVTVELYEEKPIGIRLPDQVTLAITEADPVVKGQTAASSYKPAVLENGIRILVPPFIASGERVIVDTNELTYISRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_XYLFA
Sequence: MNDLITLAQAHCQPREKKEHKLGQARLAELLPQVPGWELSNNGHALTRTFRFDNYYRTLAFVNALAFIAHCEDHHPDMSVHYGRAVVCFSTHKIGGISENDFICAAKTSALYEQGI
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: RR2_EMIHU
Sequence: MTVVTLGELLDAGVHFGHQASRWNPKMFPYIYAERNGIHVIDLVQTARLLTHAYEFVQKASQEKKSFLFVGTKRQAASIIAEEAQRCGGHYVNNRWLGGILTNWSTVQKRVEYLKELDAKEEDGTLDRLPKKEAAFLRREQEKLSHNLRGLINMTQIPDIVILVDPKRETTALLECRKLGIPIISILDTNCDPNLVDIPIPANDDAVRSVKLIISTLADGILEGKQSYQ
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNMA_LEPIN
Sequence: MSKGKIIVAMSGGVDSAVTAGLLMEDGYEVIGVNLRTWEYEAPACDTTKKSCCSPEDIRDARDVGISLKIPFYVIKMEKVFQEKVIDRFIEDYQHGKTPNPCVECNTFVKFGALFEKAKALGIDKIATGHYARIARNGERYAIANGIDVGKNQAYYLYGLSQENLKNVIFPLGEMTKPEVRQIARRMGLPVADKSESQEICFIPENDYRKFLEKKNVEFTPGFFKLKDGRIVGKHKGRENFTIGQRKGLGIAWKNPLYVISIEDDGSVILGEENETYNESFSVIDLNFQGLAPLNEGESLECRVQVRYRHIPIRCKITKMKEGLIVHPLEDVRGVTPGQSAVFYPLDSDYLLLGGIISKGSIQMRIVEPAISVLN
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR53_MOUSE
Sequence: MAVKWTGGHSSSILCLNANKDGLVASGGEGGDLVAWGEDGTPLGHMQLEGADDVTSVLFSASCPTKLYASHGETISVLDVRSLKGSLDHFHVNEEEINCLSLNETESLLASADDSGAIKILDLEKKKVTRSLKRHSNICSSVAFRPQRPQSLVSCGLDMQVMLWSLQKARPVWITNLQEDETEETEGPQTPGRLLNPALAHSVSVASCGNIFSCGAEDGKVRIFRVMGVKCERELGFKGHTLGVSQVCFLPESSLLLTGGNDGRIRLWDVSGKMEKLQKSPARHIHRKKAKRAACPTQGGNSRAPGAEDEGHAKILPKLDIEHGEKVNWLLSTKIKGNKSILVADQTSCVSVYPLNEL
What are the official names of this protein?
WD repeat-containing protein 53.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR53 family.
Protein: CNN1_SHEEP
Sequence: MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGIILCEFINKLQPGSVKKVNESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKGNKVNVGVKYAEKQERKFEPEKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHHPHNYYNSA
What is the function of this protein?
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction.  It is capable of binding to actin, calmodulin and tropomyosin.  The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
What are the official names of this protein?
Calponin-1, Basic calponin, Calponin H1, smooth muscle.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
Protein: DAPF_AZOSB
Sequence: MHIRFTKMHGLGNDFVVIDATRTPVDLTPARVKAIADRHFGVGCDQLLVVEPPGSDEVDFRYRIFNADGGEVEQCGNGARCFVRFVHDKGLTDKREIRVETRAGVIAPALRPDGLVSVDMGVPELSPARIPFVSDSDAWVQPLQLAEDTVAITAVSMGNPHAVQVVADVDTAPVARQGAEIECHPRFPARVNAGFMQVVDAGHIRLRVFERGAGETLACGTGACAAVVAGIGRGLLVSPVRVETRGGELEIAWAGPGTPVVMTGPAVTVFEGELELP
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTAS_METTE
Sequence: MVTFLEKISERAKKLNKTIALPETEDIRTLQAAAKILERGIADIVLVGNEADIKALAGDLDLSKAKIVDPKTYEKKDEYINAFYELRKHKGITLENAAEIMSDYVYFAVMMAKLGEVDGVVSGAAHSSSDTLRPAVQIVKTAKGAALASAFFIISVPDCEYGSDGTFLFADSGMVEMPSVEDVANIAVISAKTFELLVQDVPKVAMLSYSTKGSAKSKLTEATIASTKLAQELAPDIAIDGELQVDAAIVPKVAASKAPGSPVAGKANVFIFPDLNCGNIAYKIAQRLAKAEAYGPITQGLAKPINDLSRGCSDEDIVGAVAITCVQAAAQDK
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
Belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AROB_SHEON
Sequence: MAQQIQVDLGERSYPIYIGQSLMSDSETLSRYLLKKRILIVTNETVAPLYLKQVQDTMASFGEISSVILSDGEQFKDLTHLDSIFTALLQRNYGRDSVLVALGGGVIGDMTGFAAACYQRGIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQIVIIDTECLQTLPAREFAAGMAEVIKYGIMWDADFFQWLENNVQALKSLDTQALVYAISRCCEIKADVVSQDETEQGVRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGTVLAAQTAKSLGLIDESIVCRIVQLLQAFDLPVKAPESMDFESFIQHMRRDKKVLGGQIRLVLPTAIGRAEVFSQVPESTLEQVICCA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DABA_SULAA
Sequence: MKTVALKEASSILPKYWPLTMFVHHNPLHELESLHFKQALKIAKDLFDAKVYMDPSYYVDLYRKGKVRKDSLEKNIEEFLRENNFNFNKYKVRKFLTDISPSWKEYKEESFNNPSIKVPDYLLEYIKKDKGYDNLDNLFYTYIKKYLFSEILDILFDQNIYNVFFNDAVEFISRFLDEGQTSITLPFREQGYWNCFRQFYKLDKHPEDIIEEFENTFQPPSLQDYARQLYIRFFGWSSFIKFRESTPFYPYQEEFPINLEDFGSSLLYLENQYIQELNKSKIKNYFDLMAFYKENKYYVILKLFEHRKILTPKYISKLYTSKDYDNIFNKFINEEIESEAKAIVNLSTKVFDKSDYLQTYNLVKTLKEDEECYLWIKSLEDSYALNFGREFIKEYQIDEKPKAFAVFCVDVRSEALRRNLERVDNYKTFGVAGFFGVKMALIEFDKAHELLLCPAMEIPDKVVLEVPTQKTQDYEKRKKLLISLKKILEGLKNNPYTPFFAVESFGWLFGYKLFGKTLFPSVVAKIDKKIKPKPPKTFYMIDKLSEKEVDTYTDKFFYEKIYQAFEKEGIKIKDCEVKDILSKLKNNENISQNYQKVLNRYRITKQYYDYIYNRFSNIGYTLDEQVILAENFLRLIGMVEDFPEFVLLVGHGSVSDNNPYESALDCGACGGNSGYHNVRAMCMILNKKEVREKLSIRIPDGTIFIPGLHNTTTDEIEFYDEDLVPENSLDKWEEIKKDFKKAGEKTRIERLSSLPYADNPEDVIVRSIDWSEMRPEWGLSKNLGVFVGKSESRINSVLKNRFFLHSYDYKIDVDNSILKRILNGPLLIAQWINAEHYFSTVDNEKFGSGSKVYHNVVSRIGVFSGNYSDLKIGLPYQTVYVEDRPFHEPIRLIAFVEAPLEKVVEAASQTDHPMMLVKNEWIRLVVIDKEKNKVFLFSNGNFVEL
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GMHA_AQUAE
Sequence: MLEKVKKIFRESAEVKLAFVELYAQQIVDVAGIIATALKDGNKVLLFGNGGSAADAQHIAAELVGRFKKERRPLPAIALTTDTSILTALGNDYGFETIFERQVEALCMPGDVAIGITTSGNSENVIRGLKKAHDLGATTIAFTGRNGGKVAQIAHYTFIVPSYETQRIQECHITLGHVLCELVEEMVCERS
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_CLOPS
Sequence: MTKEQIIEAIKEMSVLELNELVKACEEEFGVSAAAPVAVVGGAAAGAAAEEKSEFDVVLTNAGANKIKVIKAVRELTGLGLKEAKEIVDGAPKTLKEAVAKEEAEDMKAKLAEVGAEVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PRIB_SHESH
Sequence: MATNHLVLSGTITRSRSFKSPAGIAHSVIMLEHKSQCFEAEMLRNVYCQMQVIFSGERFESVTEQLKSGVDIEVQGFIALQQSRNGQNRLVLHAENVELKT
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: SYL_SALPA
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNTLIVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFVDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMITQEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KIF3C_PONAB
Sequence: MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGASTPSSGGSGGGGGSGGGAGGERPKEASKINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRGKKAVSAPPGYPESPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEKDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQPLVPAGVNSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPAVFEMEFSHDQEQDPRALHMERLMRLDSFLERLSTSKVRKSRSWCQSPQRPPPSTTHASLASASLRPATVADHE
What is the function of this protein?
Microtubule-based anterograde translocator for membranous organelles.
What are the official names of this protein?
Kinesin-like protein KIF3C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: APT_BURM9
Sequence: MSSDRRTARDCSAVFFGEFHDVHVGRAARSRRVHSQPHPHGAGLAAARRDVSRHHAALQSAKALRVLVDLFVERYVDAKLDYIAGLDARGFIIAPIVAYELSVGFVPIRKVGKLPYATQRESYALEYGTATVEIHEDACKPGDRVVIVDDLIATGGTMMAGKNLLERLGAVVVEGAAIVDLPDLGGSALLREAGLPLYTVTEFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y389_STAAB
Sequence: MGYIKRIGLYISIFILIVMVAGCGKDNEIKEYSKETQIKNSFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGTWTLLTSFSKSNKPGVIDDEGMVLYLNRNTKKATGYYFVNKIYDDISKNQNEKKYRVELKNNKIVLLDNVEDEKLKQKIENFKFFSQYADFKDLKNYQDGSITTNENVPSYEAEYKLNNSDTNVKKLRDIYPITTKKAAILKLHIDGDIKGSSVGYKKIEYKFSKVKDQETTLRDYLNFGPSDEDS
What are the official names of this protein?
Uncharacterized lipoprotein SAB0389.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CBIJ_METJA
Sequence: MNLLLMGGTKDSVEIGKKLRDLGDLFILYTSTTDYGGKLGEEFANKVITKPLDKNELKEVIKKYNIDILVDATHPFAINASKNAIEVCKELNIKYVRFERKEEKINHPNIIYVKDFEEAARLAKKANKVFHMAGIKNLKMVVDIVGKDKVIARVLPISVSEALKILPQKQIVAMYGTFSKELNKYLIRDYNCDVIITKDSGESGGFKEKVYGALEAEAKVIVVERPKIDYPVCFDDIDELIKYIANLKI
What is the function of this protein?
Catalyzes the reduction of the macrocycle of cobalt-precorrin-6A to cobalt-precorrin-6B.
What are the official names of this protein?
Cobalt-precorrin-6A reductase.
What is the protein family that this protein belongs to?
Belongs to the precorrin-6x reductase family.
Protein: Y102_CITBB
Sequence: MEATLDGTELRVLGSLVEKDLTTPEYYPLSLNALVNACNQKSNRDPVLSLDESQVTRALDTLRFKQYALVSGSGGRVAKYRHALVEKFRFSPAELAILCELMLRGPQTVGELRGRGERMHKFSDLSEVESVLADLAERTPSLVAKLPLQPGRKEPRYCQLFSGEPDLSELAAQMEARGAGADGEKIARLEQELSELREEVASLRETIAEFRKSFE
What are the official names of this protein?
UPF0502 protein Gbem_0102.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: TXLD_CYRSC
Sequence: MKTSMFLTLTGLVLLFVVCYASESEEKEFPKELLSSIFAADSDFKVEERGCLGDKCDYNNGCCSGYVCPRTWKWCVLAGPWRR
What is the function of this protein?
Agglutinates erythrocytes.
What are the official names of this protein?
U5-theraphotoxin-Hs1d, U5-TRTX-Hs1d, Lectin SHL-1a2, Lectin SHL-Ia2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YHDJ_ECOLI
Sequence: MRTGCEPTRFGNEAKTIIHGDALAELKKIPAESVDLIFADPPYNIGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLFTIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALIDYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIVLDPFAGSFTTGAVAIASGRKFIGIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTGNLSKRSRLSEVDPDLITK
What is the function of this protein?
A beta subtype methylase, recognizes the double-stranded sequence 5'-ATGCAT-3' and methylates A-5.
What are the official names of this protein?
DNA adenine methyltransferase YhdJ, Type II methyltransferase M.EcoKII, M.EcoKII.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: E2F1_HUMAN
Sequence: MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEGIRDLFDCDFGDLTPLDF
What is the function of this protein?
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication (PubMed:10675335, PubMed:12717439, PubMed:17704056, PubMed:17050006, PubMed:18625225, PubMed:28992046).  The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase (PubMed:10675335, PubMed:12717439, PubMed:17704056).  E2F1 binds preferentially RB1 in a cell-cycle dependent manner (PubMed:10675335, PubMed:12717439, PubMed:17704056).  It can mediate both cell proliferation and TP53/p53-dependent apoptosis (PubMed:8170954).  Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812).  Directly activates transcription of PEG10 (PubMed:17050006, PubMed:18625225, PubMed:28992046).  Positively regulates transcription of RRP1B (PubMed:20040599).
What are the official names of this protein?
Transcription factor E2F1, E2F-1, PBR3, Retinoblastoma-associated protein 1, RBAP-1, Retinoblastoma-binding protein 3, RBBP-3, pRB-binding protein E2F-1.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MFS12_MOUSE
Sequence: MSPPSDDAGPGPPRTLSLAARLSFAVGHFLNDLCAGMWFTYLLLFLHSVRGYSSRGAGLLLLLGQVADGLCTPLVGYEADRASCVRCGPRKAWHLAGTVCVLLSFPFIFSPCLGCGEATPEWAALLYYGPFIVVFQFGWAATQIAHLSLIPELVTSDHEKVELTALRYAFTVVANITVYGAAWLLLHLQGSAHGEQDISVGDQLGVQDVPVFRNLALLVVGVGAIFSLLFHLGTKEGHRSQHWGNEPNEHTPLVAPAAQPLLLWKHWLREPAFYQVGMLYMTTRLIVNLSQTYIAMYLTYSLSLPKKFIATIPLVMYLSGFFSSFLMKPVNRRIGRNMTYFTGLLVILAFAAWVALADNLGVAVYGAAVLLGAGCATILVTSLAMTADLIGPHTHSGAFVYGAMSFSDKVANGLAVMAVQSLHPCPSELCCGACISFYHWVMTAVTGGVGVAAALALCSLLIWPIRIRNRDPRDRP
What is the function of this protein?
Transporter that mediates the import of cysteine into melanosomes, thereby regulating skin/hair pigmentation (PubMed:33208952).  In melanosomes, cysteine import is required both for normal levels of cystine, the oxidized dimer of cysteine, and provide cysteine for the production of the cysteinyldopas used in pheomelanin synthesis, thereby regulating skin/hair pigmentation (PubMed:33208952).  Also catalyzes import of cysteine into lysosomes in non-pigmented cells (By similarity).
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 12, Protein grizzled.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Melanosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein.
Protein: T2M5_METJA
Sequence: MDDKSYYEEIESILRQILQPIEKISFSTFIRVVSGYKIIPIDLSKKEDKELINDLAKACNEVIEEIKKTGGVKTKEGKTPKRVNEVGNHIEHYVKDVLNKYGYAITPKTKKGKQKSTGYPDIEFWYKGKKERDGRVVYIEIKTFNEKNINSSHRTFYASPSKDEEGVKIRYDAPHLCLSFKIEKLGRDYYATGFKIIDLSKLKGGIKREFNASNRELYKKDLIIYEKDLK
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GTAC-3'; the cleavage site is unknown.
What are the official names of this protein?
Type II restriction enzyme MjaV, R.MjaV, Endonuclease MjaV, Type-2 restriction enzyme MjaV.