PharMolix/UniProtQA huggingface dataset:
Protein: WNT6_MOUSE
Sequence: MLPPVPSRLGLLLLLLCPAHVDGLWWAVGSPLVMDPTSICRKARRLAGRQAELCQAEPEVVAELARGARLGVRECQFQFRFRRWNCSSHSKAFGRVLQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGCQAPRGRAPPRPSGLLGTPGPPGPTGSPDASAAWEWGGCGDDVDFGDEKSRLFMDAQHKRGRGDIRALVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTNDGKALLPAVRTLKPPGRADLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRKELSLCL
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-6.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: TIG_ECODH
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
Protein: MES11_ARATH
Sequence: MGNLCSLFTPPKPVKKRKPITKRQSSIGASSSGSGLNSNRWNNRVRSSSSRRDNKFEDALIQEHALAAAAVLFRQQNGGGGSLPFDRSASQRYQGSCSKKNQLPRSSSSRSRSSTDPLLQPHQFLNQGIKLDDLETNHFVLVHGGSFGAWCWYKTIALLEEDGFKVTAIDLAGCGINSININGIASLSQYVKPLTDILEKLPIGEKVILVGHDFGGACISYAMELFPSKISKAVFLAAAMLTNGQSTLDMFSLKAGQNDLMRKAQIFIYTNGNENPPTAIDLDKSLLKDLLFNQSPSKDVALASVSMRSIPFAPVLEKLSLSDANYGSVRRYYIETLEDNAIPVTLQENMINSSPPEKVYRLKGADHAPFFSKPQALHKLLLEIARISPA
What is the function of this protein?
Putative methylesterase.
What are the official names of this protein?
Putative methylesterase 11, chloroplastic, AtMES11.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Methylesterase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MC25A_XENLA
Sequence: MGGSESTGRKVSFGMDEEERVRVLRGVRLSDEVVNRMKDSNLPSKDQSTSTASGTTSGPTTFPSKAGPSASHSASTSKDGAHKPTARGVGHQYAEEDLYRRYEKEQALIQEELARLAKREREAAHERLSSSVLREKNITSQERRKAEHLPADLDEWAKELEQKEAELQRLNTFYREQLNSIEKKNLEIYKLTAEQFHTAASNAELRVKQRSYDPVCMDLQSNILKCYAENKQERLNCSDLAKEYGKCVSAAQKNLLFNHG
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit mic25-a, Coiled-coil-helix-coiled-coil-helix domain-containing protein 6A.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Lipid-anchor.
Protein: RPOB_SPHAL
Sequence: MATKAKSVGQALEATATKRIRKLFGNIHEAVEMPNLIEVQRESYEQFLRSDPSIGYVSGLEKTLRSVFPIRDFAGTAELDFVHYELEAPKYDVEECRQRGITYAAPMKVTLRLIVFEVDSETDTRSVLDIKEQDVYMGDMPLMTENGTFFVNGTERVIVSQMHRSPGVLFDHDRGKTHSSGKFLFAARVIPYRGSWLDFEFDAKDIVNVRIDRKRKLPVTSLLYALGMTGEEILNHFYDRLVFERAENGWKVPFMVENWRGSKPAFDVVDAKTGEVVFAAGHKISPRLANKAAKDGLDTLLIPTEEIFGRYSAYDLINESTGEIYIEAGDEVSAENLEKLDAAGIDKLVLLDIDHNNTGPWIRNTLKADKAEDRDQALSDIYRVMRPGEPPTRETAEALFAGLFFDPERYDLSAVGRVKLNMRLGLDAEDTVTTLRSEDILAVVKELVNLKDGKGEIDDIDNLGNRRVRSVGELLENQYRVGLLRMERAVKERMSSVDVSTVMPNDLINAKPAVAAVREFFGSSQLSQFMDQTNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIETPYRRVVDGKVTNEVVYLSAMEESKHTVAQANADLNPDGSFIDELISAREAGEFLMAPREQITLMDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLRAEAPVVGTGMEETVARDSGAAIAARRGGVIDQVDATRIVIRATDMVEPGKSGVDIYRLQKFQRSNQNTCINQRPLVKVGDVVRAGDIIADGPSTELGELALGKNVLVAFMPWNGYNYEDSILISERIVKDDVFTSIHIEEFEVTARDTRLGPEDITRDIPNVGEEALRNLDEAGIVYIGAEVGPGDILAGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVSGTVVEVRVFNRHGIDKDERAIAIEREEIERLKQDADDERAILNRATFSSLKDLLVGQATSAVPKGLKKGDIVTEEMLVGLDRADWWKLAVVDDKAQTALEAIKAQYDDAIKRINAKYEDRVEKLQRGDELAPGVLKMVKVFVAVKRKLQPGDKMAGRHGNKGVISRILPVEDMPFLEDGTPVDIVLNPLGVPSRMNVGQILETHLGWASRGLGQQVTRALEEWRDANPDATGGEMPEAVREKLEHVYGAEYVEDIRSRDAEGIIELASNLKVGVPFATPVFDGAKEADVSNMLTLAGLDESGQSDLYDGRTGDKFDRKVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALQAYGAAYTLQEMLTVKSDDVIGRTKVYEAIVKGDDTFEAGIPESFNVLVKEMRSLGLNVELSSYAEEDPDEGPEALPEAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: AMGO2_PONAB
Sequence: MSLRVHTLPTLLGAVVRPGCRELLCLLMITVAVGPGASGVCPTACICATDIVSCTNKHLSKVPGNLFRLMKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMDLYVGRFKLAELMFLDVSYNRIPSMPMHHINLVPGKQLRGIYLHGNPFVCDCSLYSLLVFWYRRHFSSVMDFKNDYTCRLWSDSRHSRQVLLLQDSFMNCSDSIINGSFRALGFIHEAQVGERLMVHCDSKTGNANTDFIWVGPDNRLLEPDKEMENFYVFHNGSLVIESPRFEDAGVYSCIAMNKQRLLNETVDVTINVSNVTVSRSHAHEAFNTAFTTLAACVASIVLVLLYLYLTPCPCKCKTKRQKNMLHQSNAHSSILSPGPASDASADERKAGAGKRVVFLEPLKDTAAGQNGKVRLFPSEAVIAEGILKSTRGKSDSDSVNSVFSDTPFVAST
What is the function of this protein?
Required for depolarization-dependent survival of cultured cerebellar granule neurons.  May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3.  May contribute to signal transduction through its intracellular domain (By similarity).
What are the official names of this protein?
Amphoterin-induced protein 2, AMIGO-2.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. AMIGO family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Nucleus. Note=Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons (By similarity).
Protein: EF4L4_ARATH
Sequence: MEGDVLSGFGDRHNMDGKLLQSFQKSFVDVQDILDQNRLLINEINQNHESKQPDNLGRNVGLIKELNNNIRRVASLYGDLSHSFARSVDASSEGESSGTLKSDGKANQKRFRSG
What is the function of this protein?
Component of the central CCA1/LHY-TOC1 feedback loop in the circadian clock that promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles.
What are the official names of this protein?
Protein ELF4-LIKE 4.
What is the protein family that this protein belongs to?
Belongs to the EARLY FLOWERING 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDE10_MOUSE
Sequence: MSNDSTEGTVGSCNATGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKTNKAKDEPSPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKADGFALYFLGECNNSLCVFIPPGMKEGQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHFDIGPFENMWPGIFVYMIHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETAMWISGPGPAPSKSTPEKLNVKVED
What is the function of this protein?
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides (PubMed:10359840).  Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate (PubMed:10359840).  May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition (PubMed:10359840, PubMed:14751289, PubMed:27058446).
What are the official names of this protein?
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RPF2_MOUSE
Sequence: MDALDKVLKPKTKRAKRFLEKREPKLTENIKNAMLIKGGNANATVTQVLRDMYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIEKFVSLKDIKTSKCPEGTKPMLIFAGDDFDVTEDFRRLKNLLIDFFRGPTVSNVRLAGLEYVLHFTALNGKVYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVMRRTHLASDDLYKLSMKVPKALKPKKRKNISQDTFGTTFGRIHMQKQDLSKLQTRKMKGLKKRPAENGVDDQGKKSKRIKKN
What is the function of this protein?
Involved in ribosomal large subunit assembly.  May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.
What are the official names of this protein?
Ribosome production factor 2 homolog, Brix domain-containing protein 1, Ribosome biogenesis protein RPF2 homolog.
What is the protein family that this protein belongs to?
Belongs to the RPF2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Associated with the nucleolus in an RNA-dependent manner.
Protein: ATPF_ACOCL
Sequence: MKNITDSFVSLGHWPFAGSFGFNTDILATNLINLSVVLGVLIFFGKGVLSDLLDNRRQRILSTIRNSEELRRGALEQLEKARARLRKVEMEADEYRVNGYSEIEREKMNLINATYENLERLENYKNETLHFEQQRAINQVRQRVFQQALQGALGTLNNCLNSELHFRTISANIGMLGAMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AROA_THEYD
Sequence: MNRIIKKAKTLKGEITPPPDKSISHRAVMFASLAKGQSRIKNFLWAKDPLSSLNAMKSLGVEITITDSKEIIVNGKGLHSLKESDNVIDCGNSGTTIRLLSGIVAGQRFLTVLTGDDSLRYRPMKRIINPLSLMGANIMGRAENKFPPIVIKGGFLKGISYEMPIASAQVKSAILLAGLYAKGETTLTEPHKSRDHTEKMLKNMGVNIIINDNTVKLSPVDHELNCFDITIPNDFSSAAFFIAGACLVPDSEILIKQVNLNETRTGFIEVLKNMGATIEIFNITEQGGEPVGDIFAKSSSELKGINVQGDIIPKLIDEFPILCVVATQAEGKTVIKDAKDLRAKESDRIKAMTSELKKMGVKIKEFEDGVEIEGPCKLIGTEVYSYKDHRIAMALSIAGVIAEGETTIKDANCVDISFPEFYSLLEMLQK
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPN2_HUMAN
Sequence: MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLDWLRAKLDPLRGHYFLFDCPGQVELCTHHGALRSIFSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKESIQRVLQAVDKANGYCFRAQEQRSLEAMMSAAMGADFHFSSTLGIQEKYLAPSNQSVEQEAMQL
What is the function of this protein?
Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 2, ATP-binding domain 1 family member B.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: PLCB_MOUSE
Sequence: MDPWPWLTAALLLLLLLVQLSRTARFYAKVGLYCVLCLSFSAAASIVCLLRHGGRTVDNMSIISWFVRSFKYVYGLRFEVSGQKKLEVDGPCVIISNHQSILDMMGLMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMVKENLKVWIYPEGTRNDNGDLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQIPQENSAIKEPGVLPAQ
What is the function of this protein?
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase beta, 1-acylglycerol-3-phosphate O-acyltransferase 2, 1-AGP acyltransferase 2, 1-AGPAT 2, Lysophosphatidic acid acyltransferase beta, LPAAT-beta.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: BFR_SERMA
Sequence: MKGDKKIIAHLNKLLGNELVAINQYFLHARMFKNWGLMRLNDKEYHESIDEMKHADRYIERILFLEGIPNLQDLGKLNIGEDIEEMLRSDLALELAGAKNLREGIAYADSIHDYVSRDLMIDILADEEEHIDWLETELDLIARLGIQNYAQAQILERKE
What is the function of this protein?
Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.
What are the official names of this protein?
Bacterioferritin, BFR, Cytochrome b-1, Cytochrome b-557.
What is the protein family that this protein belongs to?
Belongs to the bacterioferritin family.
Protein: YJL2A_YEAST
Sequence: MPIIGVPRCLEKPFCAPAKFPFSVKKNIRILDLDPRTEAYCLSLNSVCSKRLPCKKYFYLLNSYNIKRVLGVVYC
What are the official names of this protein?
Putative UPF0377 protein YJL222W-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0377 family.
Protein: P4R2A_XENLA
Sequence: MDVDRLQEALKDFEKRGKKEVSPELDQFLCHVAKTGETVVQWPQFKEYFVFKLEMVMDDFRTSAPEQRGSPNPNVEYIPFDEMKQRILKIVTGFNGTPFTIQRLCELLTDPRKNYNGTDKFLRGVEKNIMVVSCVYPSSEKNNSTSLNRMNGVMFPSNSQSYTDRSNVNGPGTPRPMIRPKFSLSSPMNTNGLPDSTENKESDLQQKEKSQSDSAVSDDGSQATTSRNKHSAEDSAEVEEHEVKRLKFDPDEEEEAACANPDASSEVSAEMAEEAESASTSADKGKESCQTAQASDEESLMTASESTEAESNERDSENVSVTEESSEESHHMDQSEESESACSLTSDEHNSTAAATTSTEDADPSEEEHLATSSGKSTETLTLSPMENSEEATDAPEEPMEQD
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 2-A.
What is the protein family that this protein belongs to?
Belongs to the PPP4R2 family.
Protein: FMT_SALTI
Sequence: MSDSLRIIFAGTPDFAARHLDALLTSGHNIVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQHLVADLHADVMVVVAYGLILPKAVLDMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLACPITAEDTSGSLYNKLAELGPQGLITTLKQLADGTATPEAQNEALVTHAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIDGQPVKVWQASVIEDATQSLPGTILAATKQGIQVATGKGILNLLSLQPAGKKAMSAQDLLNSRREWFIPGNRLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SYC_FLAJ1
Sequence: MPLYSSQPLKIYNSLSGEKENFKPIHEGNVGMYVCGPTVYSNVHLGNVRTFMSFDVIFRYFLHLDYKVRYVRNITDVGHIVDDVDEGEDKIAKKARLEQLEPMEVVQRYTVDFHDILKAFNFLPPSIEPTATGHIIEQIEIIKKIIDTGIGYEANGSVYFDVVKYNETNNYGVLSGRNIEDMLANTRDLDGQSDKRNPQDFALWKKAEPEHIMRWPSPWSDGFPGWHLECTAMSTKYLGNHFDIHGGGMDLKFPHHECEIAQNEACTGQSPVNYWMHTNMLTLNGKKMAKSTGNNILPGEILSGDNTILSKAFSASVTRFFMLQAHYRSILDFSDDAITAAEKGYKRLMEALEALPAIKAGSSSSVDFAAWKQACYDAMNDDFNTPILIAQLFEAVRYINLLKEGKETISAEDLKSFSTAINAFVFDVLGLSDEKAADGNNDKLEGVVNMLIGMRNQARADKNFALSDQIRDQLIALGIQLKDGKEGTSFSI
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_PSEE4
Sequence: METVVGLTAIAVALLIGLGALGTAIGFGLLGGKFLEGAARQPEMVPMLQVKMFIVAGLLDAVTMIGVGIALFFTFANPFVGQIAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HB2D_MOUSE
Sequence: MALQIPSLLLSAAVVVLMVLSSPRTEGGNSERHFVVQFKGECYYTNGTQRIRLVTRYIYNREEYVRYDSDVGEYRAVTELGRPDAEYWNSQPEILERTRAEVDTACRHNYEGPETSTSLRRLEQPNVAISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVMLEMTPHQGEVYTCHVEHPSLKSPITVEWRAQSESARSKMLSGIGGCVLGVIFLGLGLFIRHRSQKGPRGPPPAGLLQ
What are the official names of this protein?
H-2 class II histocompatibility antigen, A-D beta chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: HSLO_FINM2
Sequence: MINKLYIATDSTESFRFNIVDSTDLVQSVRDIHNTSATASAALGRLSTMAAIMSHELKNESHNITLNLQGNGQGGMLISTVNGRGEVKSYVSHPEVDLPTKSNKKLDVGSFVGNEGLLTVIKDFKLKEPYIGQTSLVSGEIAEDFSNYFYQSDQRPTVVALGVLVDTDLSIKSAGGLFIQALPGFDESLIDKLESDINKFPPISSLFVTHDDPFDILNQYFSDFDLKLLGQKEVQYLCDCNRDRVERSLISLGKETLTELIEEDGKAELVCDFCNKKYNFSKEELMELRDNI
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_SYNP2
Sequence: MSSVPPVLSGSEIRSKFLEFFNQRQHPILPSASLVPEDPTVLLTIAGMLPFKPIFLGQQDAPSPRATTSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGDYFKEQAIAWAWELSTEVFQLDPKNIVVSVFREDDEAFEIWRDKVGVNPKRIIRMGEEDNFWKSGPTGPCGPCSELYYDFKPELGDDNIDLEDDTRFIEYYNLVFMQYNRDAEGHLTPLQNKNIDTGMGLERMAQILQQVPNNYETDLIFPIIETAAKAAGIHYEKADEKTKVSLKVIGDHVRSVVHMIADGITASNTDRGYVLRRLIRRVVRHGRLIGIDGNFINQVAETAIQLSEAAYPNTRERESFIKQELEREENNFLKTLERGEKLLADIIAKEEKQISGVDAFTLFDTFGFPFELTQEIAEENGLTVDAEGYQAEMKKQQERSKAAHETIDLTVQGSLDELAEHIHPTAFLGYTDLQSQVKIEAVLVDGHRVETAEAGVVVQLICNQTPFYAESGGQIGDRGYFSGDQLVVRINDVQKESGFFVHHGKVERGSLTVGDTVNATIDRACRRRAQANHTATHLLQAALKNIVDDSISQAGSLVDFDRLRFDFNCPRALTAAELTQIEAQINTWIAEAHEGQVAVMPIAEAKAKGAVAMFGEKYGEEVRVVDFPGVSMELCGGTHVKNTAEIGLFKIISETGISSGIRRIEAVAGPAVLEYLKVRDQVVKDLGDKFKAKPEEITERVENIQAELRNTQKELEKVKAELAIAKSEALVSQAETVGEFQILVENMGDLDAKALQTAAERLQQKLGEAAVVLGSTPEDGKVSLVAAFSEGIYKGKKVQAGKFIGGIAKLCGGGGGGRPNLAQAGGRDASKLPEALHTAKQQLRETLG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA_CHLAA
Sequence: MKPPRLTDTTLRDGSHPMRHQFTRQQVATIVQALDRAGVPVIEVSHGDGLAGSSLQYGFSHTSEFDLIETARQHAERAKIAALMLPGIGTRQELKEAVARGVQVVRIATQCTEADISEQHFGLAKELGLETVGFLMMAHMRPPEELARQAKLMESYGADCVYIVDSAGAMLPQDAAARVQALKDTLSVQVGFHAHNNLGLGIANTLAALEAGADQIDGCLRGLGAGAGNAATELLAAVLDRLGLNPGLDVFSLMDAAEYVVAPIMPFQPFPDRDAITIGYAGVYSTFLLHAKRAGAQYNVDPREILVELGRRQAVAGQEDWIIDVALELSRRHQSSARKESRP
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: RL3_STAA8
Sequence: MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKADAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDASRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HIS6_RHOBA
Sequence: MLSARVIPCLDVHGGRVVKGTNFVNLRDAGDPVEVARRYEAEGADELVFLDITASHEERAILLDVVRRTAEQVFMPLTVGGGVRTVEDVRALLSAGCDKVSINSSAVTNPDFIRQAADRFGRQCIVVNIDPKRVQKDGEEFWEVHINGGRKPTGLQAVQWAKRVEELGAGEIVLTSMDADGTCDGYDIPITRAVSEAVRIPVVASGGAGNPDHLVEAIRDGKADAVLAASIFHFGTHPIGPTKQHMAEAGIRVRMPAEPFAT
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_BACTN
Sequence: MKFGIVVSEWNFNITGALLNGAVNTLKKHGVKDENILVKTVPGSFELTFGANQMMENCDVDAIIAIGCVIKGDTPHFDYVCMGATQGITELNATGDIPVIYGLITTNTMEQAEDRAGGKLGNKGDECAISAIKMIDFVWSLNK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SYT_SHEON
Sequence: MPVITLPDGSKREFAHPVSTLDVAADIGPGLAKACIAGRVNGELKDACDLIETDAELSIITAKDEEGIEILRHSCAHLLGHAIKQLWPQTKMAIGPVIDNGFYYDIDLEHKLTQDDIEALEKRMLELAKTNYDVVKRVVSWQEARDTFAARGEEYKIAILDENISKDATPALYHHEEYTDMCRGPHVPNMRFCQHFKLMSIAGAYWRGNSENKMLQRIYGTAWADKKALSTYLARLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWSIFLELERFIRRKLNQYTYQEVKGPLMMDRVLWERSGHWDKYSEAMFTTSSENREYAIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGCCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEDQVQAEVSSCIQMVYDTYSTFGFENIVVKLSTRPEKRIGDDAMWDRAEEALKQALRANNIEFTILPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDYALPSRLGATYVAEDNSRQTPVMIHRAILGSLERFLGILIEEYAGRFPTWLAPMQVVVMNITDKQADYVEEVVKFFKEQGIRASFDLRNEKIGFKIREHTLRRVPYLLVVGDQEMENKEVAVRTRDGVDLGKMRIEDFAAKIHQQISLRSLKLLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.