PharMolix/UniProtQA huggingface dataset:
Protein: FKBP6_RAT
Sequence: MSVFSRLRNGIPPSRDDCQSPYERLSQRMLDISGDRGVLKDIIREGAGDPVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPTYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLAICEEQHLVEPAELLVLLNLSFVYLKLDRPAMALRYGEQALLIDKRNAKALFRCGQACLLLTEYEQARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSGSSVGGN
What is the function of this protein?
Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.  Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis.  May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity).
What are the official names of this protein?
Inactive peptidyl-prolyl cis-trans isomerase FKBP6, Inactive PPIase FKBP6, 36 kDa FK506-binding protein, FK506-binding protein 6, Immunophilin FKBP36.
What is the protein family that this protein belongs to?
Belongs to the FKBP6 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Chromosome. Note=Does not localize to pi- bodies. Localizes to meiotic chromosome cores and regions of homologous chromosome synapsis (By similarity).
Protein: TPMT_PSEAB
Sequence: MQADFWHARWANNQIGFHLDEINPYLMRHLSRLRLQAGERILVPLCGKTLDLAWLAAQGLEVLGVELSEKAVSDFFEEHDLRPEIDQLGGFRRYRVAGITLLQGDFFALQAEHLAQCRAFYDRAALIALPPEMRERYAGHLQAVLPTRSLGLLVTIDYPQAEMAGPPFAVPDEEVRGYYAGGWRIEELERGDVLGVNWKFLERGVSWLNEAVYLLERG
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEMB_SCHPO
Sequence: MSINWVTYKEGSESDILLLENECMFDCFDGVAISILCKPPSLKSWTCTKGLLCLTNQRLVYIAKDTDCDFKDFQSPVANLKDTKLNQPFFGANYYSGTVMPVPNGGIPCEAEVKLQFNEGGIFNFVEAWNRLIQRFQEVDSVSRVQHLDPLPPYHRPSSSQDQPPHYEEAVNKS
What are the official names of this protein?
UPF0664 stress-induced protein C29B12.11c.
What is the protein family that this protein belongs to?
Belongs to the UPF0664 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MOCR_RHIML
Sequence: MLVLDRDADVPMHRQLYEKLRAEILAGHLKADTRLPPTRMMAEDLGVSRNTVITTYDALLAEGYLESRSGSGTWVATLPPDAVTARNSVGRAGAPSLSSRGMRMAAQPRDRTIPDRIAFHPGYPEIKAFPFSTWARLLKRHARYSHEDLYGYHWVTGHPRLKAAIAEYLRASRGVECAPEQVIVVNGTQAALDILARMLVDEGDICWMEEPGYIGAQNSLLSAGAKLVPLPVERDGWSLEDETRPSPRLIFVTPSCQWPLGCLMRMEDRLRLLQIGERHDAWIVEDDYDSEYRFRGRPVPAMQGLDKSGRVIYMGTFAKTLFPSLRIGFIVVPPQLADGFKRVVSNTGHYPSLLLQAALADFISEGYFATHLRRMRRLYAERQKVFVALCRRHLADWLTIDENDAGMQLVARFTRALEDEVLWRAAQGQGVNFSPLSRQFFHSPPQQGAILGYAGIDPKTMREGINSLRSAFLALESSGALPLDRATAAPRGC
What is the function of this protein?
Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism.  Could also have an aminotransferase activity.
What are the official names of this protein?
Probable rhizopine catabolism regulatory protein MocR.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: SYFA_MYCGE
Sequence: MIDQNKLITKWKKAFAKAKNLTTLVNLKNTLHNSDLKPLLQKIKTATKLSEKSSLGKLYQSLDIQLTDLLTSYKKTFEINNQVSQKPSLDVMLPATEFTNGSNNALYQVIDNLVEYFKSFLFTINFDSELTSISDCFDLLNIPKDHSSRNESDSFYIDKTSLLRTHCTATTLKAVRTSKKTNNPDIRVVSLGAVFRNDSDDATHSHQFTQLDFMWIKKGLSLANLKWFINNMITHFFGENTFTRFRLSHFPFTEPSFEIDIRCWLCQNGCSICKQTKWIEILGAGIIHPQVMNNMGIGDTENITGIAAGIGIERLAMLKYGIDDIRDFYDNNFKFLTQFTD
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN732_HUMAN
Sequence: MELLTFRDVAIEFSPEEWKCLDPAQQNLYRDVMLENYRNLISLGVAISNPDLVIYLEQRKEPYKVKIHETVAKHPAVCSHFTQDFLPVQGIEDSFHKLILRRYEKCGHENLELRKSCKRKVQKGGYNEFNQCLSTIQSKIFQCNVHVKVFSTFSNSNQRRIRHTGEKHFKECGKSFQKFSDLTQHQGIHAGEKPYTCEECGKDFKWYLIFNEYEIIHTGEKPFTCEECGNIFTTSSNFAKHKVHTGEKSYKYEECGKAFNRSSTLTKHKRIHAEEKPFTCEECGKIITSSSNVAKHKKIHTGEKLYKCQECGKVFNRSTTLTKHNRIHTGEKPYTCEECGKAFSRSSVLNEHKRIHTGEKPYKCEQCGKAFRQSATLNKHKSIHTGEKPYTCEECGKAFSRFTTLNEHKRIHTGERPHKCEECGKAFGWSTDLNKHKIIHTGEKPYKCEECGKAFGWSAYLSKHKKIHTGEKPYRCEECGKAFLCSRALNKHKTIHTGEKPYECEECGKAFGWSTYLSKHKKIHTGEKPYRCEECGKAFRRSRVLNKYKTIHTGDKTPKCKGCGKAFKWSSYLNQHNKIYTGEKL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 732.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLAW_ENTAG
Sequence: MATIGIFFGSDTGQTRKVAKLIHQKLDGIADAPLDVRRATREQFLSYPVLLLGTPTLGDGELPGVDAGSQYDSWQEFTNTLSEADLSGKTVALFGLGDQLNYSKNFVSAMRILYDLVIARGACVVGNWPREGYKFSFSAALLENNEFVGLPLDQENQYDLTEERIDTWLDKLKQAVL
What is the function of this protein?
Low-potential electron donor to a number of redox enzymes.  NifF is the electron donor to nitrogenase.
What are the official names of this protein?
Flavodoxin.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: C42S1_XENTR
Sequence: MSDFWHKLGCCVVEKPQPKKKRKRIDRSMIGEPMNFVHLTHIGSGDMGASDGLPRAGGVQEQMRSKCGRDRQWSNSGVL
What is the function of this protein?
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly.
What are the official names of this protein?
CDC42 small effector protein 1.
What is the protein family that this protein belongs to?
Belongs to the CDC42SE/SPEC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor.
Protein: CAPZB_KLULA
Sequence: MSVDEKYDAACELLYRLDPTKVKTHLQNLIALEPEIAEGLLSSIDIPLTIKKDTDANNKEFLCCDYNRDIDSHRSPWSNQYFPELSAEDLKESPFPSEPLRELEVACNNSFELYRDLYYEGGYTSTYLWDVDESTDFAGVILFKKAESDDSKWDSIHVISATHDEEGMEVTYNVTTTVILHLENLSKEQQLSLSGNLTRENSKTVKLQNVSTVEQLVPAHSSSLGSMIEDIESKLRSMLEIVYFEKTLDIYNVLRERNDDSTKLQKEQHSELIENFQKL
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit beta.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Septum.
Protein: PROA_SALNS
Sequence: MLEQMGIAAKAASYKLALLSSGEKNRVLEKIADELEAQMESILSANVQDVEQARANGLSEAMLDRLTLTPARLKAIADDVRQVCNLADPVGQVIDGGLLDSGLRLERRRVPLGVVGVIYEARPNVTVDVASLCLKTGNAVILRGGKETHRTNSATVRVIQKALKACGLPEAAVQAIDNPDRSLVNEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIFVDSSADIAPALKIIVNAKTQRPSTCNTVETLLVHQDIAERFLPALSKQMAESGVTLHGDETVMQVLHGPAKLVPLKPEELDNEFLSLDLNVVVVENMDGAITHIREHGTQHSDAILTCDMHNAARFVNEVDSAAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGFGDGTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDRGK_ARATH
Sequence: MEEIFALIVSMILIVAVIPLFFWKRRRDARSREEVAEPPQVQPRENVARAGGGRRMRRRPAASGASSSTSNVQENGSGSEDEDEDEAGGTQARASKKKEKKRQEREAQRQAEEATRESRNTKQDWYAEMRRKKDEEREAEELKLEEEEKARQAKEEEAAALEFDKWKGEFSVDAEGTTEEVQGGNQDLLSEFVEYIKKQKCVPLEDLAAEFHLRTQECINRIASLESIGRLSGVMDDRGKYIYISMEEMNAVADYIKRQGRVSISHLASKSNQFIDLEPKVQHQLTEEISGMEEISVS
What are the official names of this protein?
DDRGK domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDRGK1 family.
Protein: PSBM_CUSRE
Sequence: MEVNILAFIATALLILVPTAFLLIIYVKTAS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: MANF_ASPCL
Sequence: MRSLSSVALLSAIGAASAQAGPWGQCAGISHTGPTTCESGWSCVYLNDWYSQCQPGAATSSSTTVSSTKQPSSTVAAPSSTTSAHTLPTGSGSFAKTDGLKFNIDGKTKYFAGTNAYWLPFLTNNADVDAVFDHLQQTGLKILRTWGFNDVNTIPGSGTVYFQLHDKATGTSTINTGANGLQRLDYVISAAEKHGIKLIIPFVNNWDDYGGMNAYINAYGGSKTEWYTNEKIQSVYQAYIKAIVSRYRDSPAIFAWELGNEPRCKGCSTDVIYNWVAKTSAYIKSLDPNHMVTTGEEGMGLTVDSDGSYPYSKDEGSDFARNLAAPDIDFGVYHLYVADWGVSDNAWGNRWIKSHAKVCEAAGKPCLFEEYGIKDDHCGDSLKWQKTSLTTTANSADLFWQYGQQLSTGASPNDHYTIYYGTDDWKCAVIDHISQI
What is the function of this protein?
Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.
What are the official names of this protein?
Mannan endo-1,4-beta-mannosidase F, Endo-beta-1,4-mannanase F.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPA_CHLFF
Sequence: MHRSTLPKRARVLKRKQFLYISRTGSHCQGSQVIFQVAPSKYPGCCKLGITVSKKFGKAHKRNYFKRLVREAFRQKRHSLPACQIVVMPKNKQQPRFRDLLQDFSQQIPEAVESKCAKNKLTTGVEYNPKNEKCETAPL
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: DCUP_HELPH
Sequence: MIFIDACFRKETPYTPIWMMRQAGRYLREYQESRKKAGSFLELCKNSDLATEVTLQPVEILGVDAAILFSDILVVPLEMGLNLEFIPKKGPHFLETITDLKSVENLKVGAYKQLNYVYDTISQTRQKLSKEKALIGFCGSPWTLATYMIEGEGSKSYAKSKKMLYSEPEVLKALLEKLSLELIEYLSLQIQAGVNAVMIFDSWASALEKEAYLKFSWDYLKKISKELKKRYAHIPVILFPKGIGAYLDSIDGEFDVFGVDWGTPLTAAKKILGGKYVLQGNLEPTRLYDKNALEEGVEGILKVMGNQGHIFNLGHGMLPDLPRENAKYLVQLVHAKTRR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_PSEPW
Sequence: MVQRSKSSANWLREHFNDPFVKQAQKDGYRSRASYKLLEIQEKDRLIRPGMSVIDLGAAPGGWSQVTSRLIGGQGRLIASDILEMDSIPDVTFIQGDFTQDEVLQQILDAVGDSHVDLVISDMAPNMSGTPEVDMPRAMFLCELALDLATRVLKPGGDFLIKIFQGEGFDMYLKDVRTKFDKVQMRKPSSSRDRSREQYLLGKGFKGA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN276_MOUSE
Sequence: MKRDRLGRFLSPGIARQRGGSGGGCGSGRTRGRPSRSGGTSADGAAAQLSWGSMTRSCGDTGDDGTDEAGAGRTLAMGHCRLCHGKFSSRSLRSISDRVPGETSERLSPGERVFIRDFQRLLGVAVHQDPALPQSVCKNCYTQFYQCHSLLRTFLQRVNVSPAGQRKPCTKVGVQPTTVAEEGACVADLIASSPRCLHGLVGWVHEHAVSCGSLPSLQRTLSSEYCGIIQAVWGCDQGHDFTMDTASSCRALFLDSALAVKWAWGKDLSPRLAQNSESNPTGAASRLCQARETQVGSETKTLPSVDVALLHSHGDSVGPGLGPCTQPHLAPSEAPGQLGETQVPSSTSDDRVKDEFSDLSEGDFLSEDESDKKQTPQSSDESFEPYPEKKVSGKKSEGREAKRPEEPKIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQAQDRALPLEAEPPPGPLSPSGTMEGQAVKPEPT
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 276, Zfp-276.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: GCH1_STRP1
Sequence: MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKMYAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSDGRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRGIKKPGSKTITTTARGLYKESRAERQEVISLMTKD
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RSMA_RUEST
Sequence: MSAIDNLPPLREVIATHQLSARKSLGQNFLLDLNLTAKIARQAGDLTGCDVLEIGPGPGGLTRGLLSEGARKILAIEKDQRCLPALEDIAAAYPGRLEVINGDALEIDPLAHLTPPIRVAANLPYNVGTELLVRWLTPKEWPPFWQSLTLMFQREVAERIVAQPGSKAYGRLAILAQWRAEARIALSLPPGAFTPPPKVSSAVVHLTALPEPRYPADAAILSRVVAAAFNQRRKMLRASLKGVSPQIEDHLNAAGIPPTERAEQVSVEDFCALARSLEKG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX19_BOVIN
Sequence: MAAAEGDGGVRAEADRELEELLESALDDFDKAKPSPAPPPTTTAPDASGPQKRSPGDTAKDALFASQEKFFQELFDSELASQATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDATSQQEFTSCLKETLSGLAKNATDLQNSGMSEEELTKAMEGLGMDEGDGEGTILPIMQSIMQNLLSRDVLYPSLKEITEKYPEWLRAHRDSLPPEQFEKYQEQHSVMGKICEQFEAETPTDSEATQKARFEVVLDLMQQLQDLGHPPKELAGEMPPGLNFDLDALNLSGPPGANGEQCLIM
What is the function of this protein?
Necessary for early peroxisomal biogenesis.  Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs).  Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3.  Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53 (By similarity).
What are the official names of this protein?
Peroxisomal biogenesis factor 19, Peroxin-19, Peroxisomal farnesylated protein.
What is the protein family that this protein belongs to?
Belongs to the peroxin-19 family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Lipid-anchor; Cytoplasmic side. Note=Mainly cytoplasmic. Some fraction membrane- associated to the outer surface of peroxisomes.
Protein: STE7_CANAX
Sequence: MTRTTRIDTQEATKHKDLPPVPSPLSLSSNPNPECLMESKSLGRKNFKKLSLDASPVKSTSGSLRSSDMMSIKEPTSLRQKRQRPPPILHLPTASSSATSTPTSNITGSSSASSIQFAQKSPGSGVIVSQTLSRPSSAGGIPSSGYSSLNVNQSNRNVDPDNVVSTDMILNQISNLDLTSMNHHRQHYQNSHHHLPTTNRKRQTVISSISPTKSSAASSPLEPQIQSLPASSQSPIATTSALKLNNKDLLTLKQLGSGNSGSVSKILHIPTQKTMAKKIIHIDSKSVIQTQIIRELRILHECHSPYIIEFYGACLNNNNTIVICMEYCNCGSLDKILPLCENKQFPTFVLKKLSFAILSGLTYLYTTHKIIHRDIKPNNVLMTHKGEFKLCDFGVSRELTNSLAMADTFVGTSMYMSPERIQGLDYGVKSDVWSTGLMLIELASGVPVWSEDDNNNDDDEDDEDDAYVRQGSIAAERNGQNSPSRSRKNKQKGNGYNSYNGPEGILDLLQRIVNEDAPTLTNKINPVTKLPYDKYLCQFIDLCLIKDDSVRKTPWQLLEDKEHFFKGVEEGVYDKEHKSWAKKIRKCKV
What are the official names of this protein?
Serine/threonine-protein kinase STE7 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: SOAT1_MOUSE
Sequence: MSLRNRLSKSGENPEQDEAQKNFMDTYRNGHITMKQLIAKKRLLAAEAEELKPLFMKEVGCHFDDFVTNLIEKSASLDNGGCALTTFSILEEMKKNHRAKDLRAPPEQGKIFISRQSLLDELFEVDHIRTIYHMFIALLILFVLSTIVVDYIDEGRLVLEFNLLAYAFGKFPTVIWTWWAMFLSTLSIPYFLFQRWAHGYSKSSHPLIYSLVHGLLFLVFQLGVLGFVPTYVVLAYTLPPASRFILILEQIRLIMKAHSFVRENIPRVLNAAKEKSSKDPLPTVNQYLYFLFAPTLIYRDNYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYVYKDLLWFFSKRFKSAAMLAVFALSAVVHEYALAICLSYFYPVLFVLFMFFGMAFNFIVNDSRKRPIWNIMVWASLFLGYGLILCFYSQEWYARQHCPLKNPTFLDYVRPRTWTCRYVF
What is the function of this protein?
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol.  Plays a role in lipoprotein assembly and dietary cholesterol absorption.  Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) preferentially as susbstrate: shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions.
What are the official names of this protein?
Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol acyltransferase 1, ACAT-1, Cholesterol acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NADE_STAHJ
Sequence: MTNLQDIVVNEMKVKKHIDSEQESREIIQFIKSYVQSHSFIKSLVLGISGGQDSTLTGKLAQLAVEELRNEGRDCQFIAVKLPYGVQKDAEEVEDALNFIHPDEIITVNIKPAVDQSVKSLNEAGIELTDFQRGNEKARERMKVQFSIASNRSGIVIGTDHSAENITGFYTKYGDGAADIAPIFGLNKRQGRQLLKYLNAPKHLYEKVPTADLEDDKPQLPDEEALGVTYDQIDDYLEGKHISSEARDTIENHYVKNAHKRELAYTRYTWPKN
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: GCSH_MYCLE
Sequence: MSDIPSDLHYTAEHEWIRRSREDTVRVGLTDFAQSTLGDVVFVQLPEVGAELAAGKSFGEVESTKSVSDLYAPVSGTVSAVNTDLEGSPQLVNSDPYGAGWLLDVHVSDVGALESAIATLLDAETYRGTLTK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: DRB4_ARATH
Sequence: MDHVYKGQLQAYALQHNLELPVYANEREGPPHAPRFRCNVTFCGQTFQSSEFFPTLKSAEHAAAKIAVASLTPQSPEGIDVAYKNLLQEIAQKESSLLPFYATATSGPSHAPTFTSTVEFAGKVFSGEEAKTKKLAEMSAAKVAFMSIKNGNSNQTGSPTLPSERQEDVNSNVKSSPQEIHSQPSSKVVMTPDTPSKGIKVNEDEFPDLHDAPASNAKEINVALNEPENPTNDGTLSALTTDGMKMNIASSSLPIPHNPTNVITLNAPAANGIKRNIAACSSWMPQNPTNDGSETSSCVVDESEKKKLIMGTGHLSIPTGQHVVCRPWNPEITLPQDAEMLFRDDKFIAYRLVKP
What is the function of this protein?
Double-stranded RNA-binding protein involved in RNA-mediated post-transcriptional gene silencing (PTGS).  Functions in the trans-acting small interfering RNAs (ta-siRNAs) biogenesis by binding and assisting DICER-LIKE 4 (DCL4).  Required for DCL4 activity.  Required for the 21 nucleotide ta-siRNAs production of the TAS3 transcript in leaves but not in flowers.  Plays an important role in silencing RNA of both DNA and RNA viruses.  Involved with argonaute 7 (AGO7) and RDR6 in turnip crinkle virus (TCV) silencing.  May not be directly involved in viral siRNA production.  May stabilize the 21 nucleotide viral siRNAs and deliver them to the RISC complex.  Targeted by the viral silencing suppressor (VSR) transactivator/viroplasmin (TAV) protein of the cauliflower mosaic virus (CaMV) that inactivates DRB4 function in RNA silencing.  Probably not involved in the guide strand selection from RNA duplexes.  Involved in leaf morphology through its function in ta-siRNA-mediated silencing.
What are the official names of this protein?
Double-stranded RNA-binding protein 4, dsRNA-binding protein 4, AtDRB4.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRHO_CHLCV
Sequence: MKKNYYALAYYYLTRVDNPQLEIALHKELFKDLDVSCRIYISEQGINGQFSGYQPDAEHYMNWLRQRPGFSNVKFKIHHIEENIFPRVTVKYRKELVALGCDVDLTTQGKHISPKEWHEKLKENRCLVLDVRNNYEWKIGHFENAVLPDIQTFREFPEYAERLSKEHDPATTPVMMYCTGGIRCELYSSLLLEKGFKEVYQLDGGVIAYGQAVGTGKWRGKLFVFDDRLAVPIDETDTDVAPIAQCSHCGVGCDTYYNCANTDCNNLFICCEDCIDSTKGCCSQECSQAPRIRAFSPSRGNKPFRRMHLCEQVECEQVEKKASSCCCSCSH
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RL29_CLOBB
Sequence: MKARELKELRSSNPQDLTLKLGDLKAELFNLRFQLATGQLENPMRIREVKKSIAQIKTILREDEMRALEQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SMP3_CANGA
Sequence: MDNKLIWLLPAIGLVVALQPSYIHPDEHFQTLEMLMIKFYGISGTVPWEFEPTNNARSYFPLYAFYGPLFYLMRDILKVQNPLNILRIIRFYNFMLYLSVLYYALPKLVNENKLQNKGRVNEALVFILSSYITWCYQCHSFSNSLETILLLLVLSNYTDILSNKAGLLQLVSTGFLISVGTFTRISFPAFLLLPSIQVFLKVLYRKWIQMVVIAVSMTLSTSIIVYFDTFMYESDEIIIAPLKNVVYNLNVDNLAKHGLHPRYTHLLVNIPLILGPGLLMIRNTKNDFLNLPLLSIISSLFFLSALRHQELRFLLPVVPLFSTLLTRFRYRPYLFRIWLVFNAAMCIIMGIFHQGGVIPMISNINAEQDLTIDIWWKTYSPPTWLYNNDILTVSTTSIVNNIENLDLVQFNVKTNHVVDLKGCDFDLVLEAIQNFRINGVKSLRLIVPNSMTSNVAALNQTYLVTKENSVFPHLDLDHLDSGIQNIIGLSEYKVSL
What is the function of this protein?
Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly.  The presence of a fourth mannose in GPI is essential in fungi (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 4, GPI mannosyltransferase IV, GPI-MT-IV.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGZ subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.