PharMolix/UniProtQA huggingface dataset:
Protein: KCNU1_MOUSE
Sequence: MSQTLLDSLNQKELTETSCTIEIQAAFILSSLATFFGGLIILFLFRIALKSSRSWKYVKGPRGLLELFSSRRIEANPLRKLYFHGVFRQRIEMLLSAQTVVGQVLVILVFVLSIGSLVIYFINSMDPVRRCSSYEDKIVHGDLSFNAFFSFYFGLRFWAAEDKIKFWLEMNSIVDIFTIPPTFISYYLKSNWLGLRFLRALRLLELPKILQILQVIKTSNSVKLSKLLSIVISTWFTAAGFLHLVENSGDPWLNGRNSQTMSYFESIYLVTATMSTVGFGDVVAKTSLGRIFIVFFTLGSLILFANYIPEMVELFSTRKKYTKPYEAVKGKKFIVVCGNITVDSVTAFLRNFLHWKSGEINIEIVFLGETLPCLELETLLKCHTSCTNFVCGTALKFEDLKRVAVENSEACLILANHFCSDLHDEDNSNIMRVLSIKNYYPQTRVIIQILQSQNKVFLSKIPNWDWSAGDNILCFAELKLGFIAQGCLVPGLCTFLTTLFIEQNQKVFPKHPWQKHFLNGLKNKILTQRLSNDFVGMTFPQVSRLCFVKLNLMLIAIQHKPFFHSCCTLILNPSSQVRLNKDTLGFFIADSSKAVKRAFFYCSNCHSDVCNPELIGKCNCKIKSRQQLIAPTIMVMKSSLTDFTTSSHIHASMSTEIHTCFSREQPSLITITTNRPTTNDTVDDTDMLDSSGMFHWCRAMPLDKVVLKRSEKAKHEFQNHIVVCVFGDAQCTLVGLRNFVMPLRASNYTRQELKDIVFIGSLEYFQREWRFLRNFPKIHIMPGSALYMGDLIAVNVEQCSMCVILATPYKALSSQILVDTEAIMATLNIQSLRITSPTPGSSKSEVKPSSAFDSKERKQRYKQIPILTELKNPSNIHFIEQMGGLDGMLKGTSLHLSTSFSTGAVFSDTFLDSLLATSFYNYHVVELLQMLVTGGISSEMEHYLVKEKPYKTTDDYEAIKSGRTRCKLGLLSLDQTVLSGINPRKTFGQLFCGSLDNFGILCVGLYRMIDEEEPSQEHKRFVITRPSNECHLLPSDLVFCAIPFNTTCGKSDSSPSIQAQNNSTNATTPLAQGSNFFDSHHADESHDLYPVDDTGERWSQHHHSRVYPLDTLDASDIVQEK
What is the function of this protein?
Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+).  Represents the primary spermatozoan K(+) current.  In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+).  Critical for fertility.  May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.
What are the official names of this protein?
Potassium channel subfamily U member 1, Calcium-activated potassium channel subunit alpha-3, Calcium-activated potassium channel, subfamily M subunit alpha-3, Pore-forming subunit of the sperm-specific alkalization activated K(+) current, KSper, Slowpoke homolog 3, mSlo3, pH-sensitive maxi potassium channel.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa5.1/KCNU1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AP1_VITVI
Sequence: MGRGRVQLKRIENKINRQVTFSKRRTGLLKKAHEISVLCDAEVALIVFSTKGKLFEYSTDSCMEKILDRYERYSYAERQLTATDPESQGNWSLEYSKLKAKIELLQRSQRHFLGEDLDSLSLKELQNLEQQLDTALKHIRSRKNQLMYESISELQRKEKAMQEQNNMLAKEIKEKEKTVAQQTHWEQQNHGLNTSSFLLPQQLPCLNMGGTYQGEAHGARRNELDLTLEPIYPSHLGCFTT
What is the function of this protein?
Probable transcription factor involved in flower development.
What are the official names of this protein?
Agamous-like MADS-box protein AP1, APETALA1-like protein, AP1-like protein, VvAP1, VviAP1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL23_PASMU
Sequence: MIQQERLLKVLKAPHVSEKATNNAEKSNTIVFKVALDANKVEIANAVEQLFEVKVDSVRTVVVKGKTKRHGARMGRRSDWKKAYVTLQEGQSLDFVEGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL28B_SCHPO
Sequence: MPTHTSKTRKLRGHVSAGHGRIGKHRKHPGGRGKAGGLQHLRSHFDKYHPGYFGKVGMRRFHLMKNPLWRPTVNLDRLWTLVPNETREKYLGKNTEVAPVINVLQSGYGKVLGKGRLPDTPVIIQTRYVSRRAEEKIKQAGGVVELIA
What are the official names of this protein?
60S ribosomal protein L28-B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: EFTU1_YERPN
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGSARAFDQIDNAPEEKARGITINTSHVEYDTPARHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPVIRGSALKALEGDAEWEAKIIELAEALDSYIPQPERAIDRPFLLPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIIDTIKTTCTGVEMFRKLLDEGRAGENVGVLLRGTKRDDVQRGQVLAKPGSIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTIDVTGTIELPEGVEMVMPGDNVNMVVNLIAPIAMDDGLRFAIREGGRTVGAGVVAKVIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFI_SALPK
Sequence: MDLASLRAQQIELASSVCREDRLDKDPPAFIGGADVGFEQGGEVTWAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEQLSQKPDLLFVDGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSTEPGALSPLMDKGEQLAWVWRSKARCNPLFIATGHRVSTDSALAWVQRCMKGYRLPEPTRWADAVASGRPAFVRWQEIQR
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPRB_MYCBO
Sequence: MWWFRRRDRAPLRATSSLSLRWRVMLLAMSMVAMVVVLMSFAVYAVISAALYSDIDNQLQSRAQLLIASGSLAADPGKAIEGTAYSDVNAMLVNPGQSIYTAQQPGQTLPVGAAEKAVIRGELFMSRRTTADQRVLAIRLTNGSSLLISKSLKPTEAVMNKLRWVLLIVGGIGVAVAAVAGGMVTRAGLRPVGRLTEAAERVARTDDLRPIPVFGSDELARLTEAFNLMLRALAESRERQARLVTDAGHELRTPLTSLRTNVELLMASMAPGAPRLPKQEMVDLRADVLAQIEELSTLVGDLVDLSRGDAGEVVHEPVDMADVVDRSLERVRRRRNDIHFDVEVIGWQVYGDTAGLSRMALNLMDNAAKWSPPGGHVGVRLSQLDASHAELVVSDRGPGIPVQERRLVFERFYRSASARALPGSGLGLAIVKQVVLNHGGLLRIEDTDPGGQPPGTSIYVLLPGRRMPIPQLPGATAGARSTDIENSRGSANVISVESQSTRAT
What is the function of this protein?
Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host.  In response to environmental signals MprB acts as both a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to MprA, and a protein phosphatase that dephosphorylates phospho-MprA (By similarity).  MprB/MprA up-regulates expression of mprA and pepD.
What are the official names of this protein?
Signal transduction histidine-protein kinase/phosphatase MprB, Mycobacterial persistence regulator B.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FKBP4_USTMA
Sequence: MSATPIGFFGLKLVPGKVHRMDVSRDFKITNVSYADQPKSNTKTLVKIHYTHVPGFEDDYDEEEQEKEPKSTDEEEEIEEKVYTLCSLNGANKDHAVVDLQFCQEELIGFSITGDAPVDLVGNYVAPPDFFDQDPSDSELYSDDEDDDEDMYGLDSDDFDDDDDDDMDEDPDRFEELVESSASKPKKAIEAAPLADSKKRAAEKPVKETAAKKLKADASAASAASTPTKAIETKGEKQTKGAKDTKPKSETVEKKTVDKSTSKMTTTKLPSGLVIEEKSAGSGPPCKAGQKVGMRYVGKLTNGKVFDQCTSGKPFYFKLGKGEVIKGWDEGVKGMRVGAERRLTCPPKLAYGNQKIPGIPANSTLVFDVKLVEIK
What is the function of this protein?
PPIase that acts as a histone chaperone.  Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail.  Proline isomerization influences H3 methylation thereby regulating gene expression.
What are the official names of this protein?
FK506-binding protein 4, Histone proline isomerase, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SHH_DEVPA
Sequence: YGRRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTVMNHWPGVKLRVTEGWDEDGHHFEESLHYEGRAVDITTSDRDKSKYGTLSRLAVEAGF
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.  Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes.  Displays floor plate-inducing activity.  Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes.  In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).
What are the official names of this protein?
Sonic hedgehog protein, SHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Sonic hedgehog protein C-product: Secreted, extracellular space. Sonic hedgehog protein N-product: Cell membrane; Lipid-anchor. The C-terminal peptide diffuses from the cell, while the N-product either remains associated with lipid rafts at the cell surface, or forms freely diffusible active multimers with its hydrophobic lipid-modified N- and C-termini buried inside.
Protein: MARCS_BOVIN
Sequence: MGAQFSKTAAKGEATAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAEPGAKEELQANGSAPAADKEEPAAAGSGAASPAAAEKDEPAAAAPDAGASPVEKEAPVEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEGAAGASAEGGKDEASGGAAAAAGEAGAAPGEPTAAPGEEAAAGEEGAAGGDPQEAKPEEAAVAPEKPPASEEAKAVEEPSKAEEKAEEAGVSAAGCEAPSAAGPGVPPEQEAAPAEEAAAAPASSACAAPSQEAQPECSPEAPPAEAAE
What is the function of this protein?
MARCKS is the most prominent cellular substrate for protein kinase C.  This protein binds calmodulin, actin, and synapsin.  MARCKS is a filamentous (F) actin cross-linking protein.
What are the official names of this protein?
Myristoylated alanine-rich C-kinase substrate, MARCKS, ACAMP-81.
What is the protein family that this protein belongs to?
Belongs to the MARCKS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cytoplasm.
Protein: EX7L_AZOC5
Sequence: MPSDSMTDLPETRANAPEWTVSELSFALRRTVEDAYGHVRVRGEISGYRGPHSSGHAYFSIKDEGARLDAVIWKSAFARLKLRPEEGLEVVAVGKLTTYPGKSGYQIVIESLEFAGAGAIMAMLEERKRRLAAEGLFDAARKQELPFLPKVIGVVTSPTGAVIRDILHRLSDRFPRQVIVWPVRVQGETSAAEVAEAIRGFNALPEGGPIPRPDVLIVARGGGSLEDLLGFSDEAVVRAAAESFIPLVSAVGHETDVTLIDFAADVRAPTPTAAAEMVVPVRADLLAGIDAYGERLSAAPRRLLERRRADFRALARHLPTADALLAVPRQRLDAAGERLPRALRANAAAHRLAFEAVRTRHSASAFRLRLARAQDRVAALGGRLQWGLTGLVSRRSERLSAMTARFGSARAASLRAHVLHLSRCRERLSVLSTRAQRAVRHDLRERTNRLAAMEQLLKALSYRGVLARGFALVRDAQGGAVRAAGAVVPGARLELEFADGRLGVQALGEGAPVEPPQAARPSKGARTKAAQPSLFDD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC3_DESDE
Sequence: VDAPADMVIKAPAGAKVTKAPVAFSHKGHASMDCKTCHHKWDGAGAIQPCQASGCHANTESKKGDDSFYMAFHERKSEKSCVGCHKSMKKGPTKCTECHPKN
What is the function of this protein?
Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin.
What are the official names of this protein?
Cytochrome c3.
What are the subcellular locations of this protein?
Periplasm.
Protein: VSPPA_AGKPL
Sequence: MVLIRVLANLLILQLSYAQKSSELVVGGDECNINEHRSLVVFFNSSGFLCGGTSINQEWVLTAAHCDSKNFQMLFGVHSKKILNEDEQTRDPKEKFICPNRKKDDERDKDIMLIRLDSPVSNSEHIAPLSLPSSPPSVGSVCRIMGWGTISPTKVTYPDVPHCANINILDHAVCRAAYPTLLAESSTVCAGTQQEGKDTCGGDSGGPLICNGQIQGIVSWRAHPCGQGLKPGVYTKVFDYTDWIQSIISGNTDVTCPP
What is the function of this protein?
Snake venom serine protease that activates plasminogen.  Shows a preferential cleavage at Arg-|-Xaa instead of Lys-|-Xaa bonds.
What are the official names of this protein?
Venom plasminogen activator, APL-PA, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LUXM_VIBHA
Sequence: MKLMLSLGSLSANSLPIEKKQQVLIDLVIRTYQSHERTELFKAITEYRKNQLIALFPEHANKSYSIIFELMDYRDLIERYPSTLSEEATLLEKVVGQCFMHWLDFWCECEIAAIKAKFPLKENELPAPQLLFEDSAYYGALVERVEDTQLMVQIPSHPQAMPLSDAITLSNLELFIQGEKWYEMLSLLSLSQVGKHFIVLKHPVQDSCPTLVASALIQNWSVRDTWLSYAPQFSNEQWNYCFPSYGYSEFTRLQLFTPSSLSKCYSLPEFDNEFKLQLSDTQAVCEVLRLTVSGNAQQKLYFLYLAQKELMSVLHQAGYKIGFTIIEQPFMLNFYRAIDAKAYFHSGYCDLNDDGKQTYRGFWNFEMMVKAFSNIDFRGYKRAVRASRKRGSLERDEHV
What is the function of this protein?
Required for the synthesis of an autoinducer molecule beta-hydroxybutyryl homoserine lactone, which binds to LuxN and thus acts in bioluminescence regulation.
What are the official names of this protein?
Acyl-homoserine-lactone synthase LuxM, AHL synthase LuxM.
What is the protein family that this protein belongs to?
Belongs to the LuxM / VanM family.
Protein: BAMA_PHOLU
Sequence: MAMKKLLIASLLFGSAAAYGADGFVVQDIHFEGLQRVAVGAALLNMPVRVGDTVSDEDIGRTIHALFATGNFEDVRVLRDGNTLIVQVKERPTIASITFSGNKSVKDDMLKQNLEASHVRVGEALDRTMLSNIERGLEDFYYSVGKYNASVKAVVTPLPRNRVDLKLVFAEGVSAKIQQINIVGNKSFSSDELLNRFQLRDDVPWWNLTADQKYQKQKLTGDLEALRSFYLDRGYARFNIDSTQVSLTPDKKGIYVTINMTEGDQYKISGIDLNGNMAGYQSEITKLAAIEPGSLYNGTQVTKMENDIKNLLGRYGYAYPRVMTQPEINDQDKTVKLHVNIDAGNRFYVRKIRFSGNDTTKDSVLRREMRQMERAWLGSDLVELGKERLNRLGYFETVDVETQRIPGSPDQVDVVYKVKERNTGSLNFGVGFGTESGVSFQIGAQQDNWLGTGNAVGINASKNDYSTYAELSFTDPYFTINGVSLGGRVFYNDFRADDAELSGYTNQSYGISGFLGFPINENNSLNFGLNYIHNSLSDMLPQVAMWRYLRSMGEKPDLESKAEFKADDFALTMGWTYNNLDRGFFPTSGVKSTLNGKVTIPGSDNEFYKVTLDTSAYYPINDDRTWVILGRSRLGYGDGLGGKELPFYENFYAGGSSTVRGFRSNNIGPKAIYLYKDGSPKKESPSRDAVGGNAMAVASLELITPTPFLDSKYSNSVRTSFFIDSGTVWDTDWNDSAVMKSKGIPDYSKPGNIRVSAGIALQWMSPLGPLVFSYAKPIKDYEGDRSEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS3_RHOCS
Sequence: MGQKVNPVGLRLGINRTWDSRWFAARDYAVLLHQDLKLRKFLQGKLQAAGVSRIVIERPAKKARVTIHTARPGVVIGKKGADIEKLRGTLGTMAGGEVSLNIVEIRKPELDARLIAENIASQLERRVAFRRAMKRAVQSAMRLGAQGIRINCSGRLGGAEIARLEWYREGRVPLHTLRADIDYGTATAKTTYGTCGVKVWVFKGEILAHDPMAQDKRAMEQAPAR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: Y1784_ARCFU
Sequence: MIYEPAEDSELLLEAALRELKPDDEVIEVGAGSGFVAERLKGKCKCILTTDISPFAAMELRRKGLDVVMTDIAKGIRKKFSLVLFNPPYVELEDELRRGDWLDVAIDGGKKGVKVIKKFLDSLDEIMAERGRAILIASSQNEPDVFDLIDERGFRYEIVGERGLFFEKLFAIKIWKE
What is the function of this protein?
Putative protein methyltransferase using S-adenosyl-L-methionine as the methyl donor.  May methylate a Gln residue in target proteins (By similarity).
What are the official names of this protein?
Putative protein N5-glutamine methyltransferase AF_1784, M.AfuHemKP.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal PrmC-related family.
Protein: SUCC_RICTY
Sequence: MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINEAIDKLNTKVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGINLVTHQTGPQGQKVNHLYIESGCDILKEYYFSIVFDRSASCITFIASTEGGVDIEAVAEKMPEKIIKFAVDPATGLQDFHMRGIAYGLGFKDSQAKQMKEIVKSVYNAFIETDATQIEINPLIINSYKNLLALDAKITFDDNGLFKHPNITAMRDHDEEDPLETRAANAGLSYVKMDGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKEALKIILSDKEVKGILVNIFGGIMRCDIIAEGIIAAARDIGITVPLVVRLAGTNVEKGKEILSNSNLKIIPAHDLADAANKIVEAIR
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: LEP_RICPR
Sequence: MNRDNINSNKTVKQEFGSFAFVICIALVIRILIMEPFTVPTGSMKATILENDYIFSTKYSYGYSNYSLSFFDFIHLFKGRVFAREPERGDIVVFRPPNDMSVRYIKRLIGLPGDKIQLIDDVIYINDKKIERTEVGTYIGEDGIKYLKFKETLPNGRTYFSYKLAPIFGVIPSDRYSNTDVFYVPEGQYFFLGDNRDRSNDSRVNLGFVPFENFIAKAQFIWFSTKITWWDNDIGIINLILKLKPWIESVRLSRIFKNLYNVDE
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: RL15E_HALSA
Sequence: MARSFYSHIKEAWEDPDDGKLAELQWQRKQDWRKEGAIERVDRPTRLDKARELGYKAKQGVVVVRVSVRKGTARKSRFKAGRRTKRQGVNRIGRAKNLQRIAEERASRKYVNLRTLNSYWVGEDGSQKWFEAILLDPEHGAIQNDDDLNWICDDSHKNRVFRGKTSAGRRARGLQNRGKGTEGLRPSTNADKRNKS
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: YCFP_ECOLI
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: ISDF_STAAW
Sequence: MMIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLITKFTTGNNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLEILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNRI
What is the function of this protein?
Part of the binding-protein-dependent transport system for heme-iron.  Responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Probable heme-iron transport system permease protein IsdF, Iron-regulated surface determinant protein F, Staphylococcal iron-regulated protein G.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRB_LAWIP
Sequence: MQEKNVFNWLHKDLLDIDQLSQTDIFNILNTASSLDETNSRVIKKLPTLRGKNIILFFAEPSTRTKVSFEIAGKRLSADTIGVNASSSSIQKGESLKDTALTLQAMSPDVIVLRHSSSGAALFLADLLECSVINAGDGWHAHPTQALLDVFSLWKVWGNHFHGKEVLIVGDTAHSRVCRSNVTLLNLMGVKVRLCSPRTLLPSGVEHWPVEIYTDLHQAICGVDAVICLRVQLERHKKSFFPSIEEYAKRFCLTPKHLMSAKTEAKVLHPGPFLRGVDLASSLIETPQSLIFDQVSAGIAIRMAILFLFLTCNDL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RLMN_VIBC1
Sequence: MTTEKINLLDFDRKGMRQFFADELGEKAFRADQVMKWIYHFGVDDFDNMTNINKKLREKLQHKCEIKAPTVAEAQHSSDGTIKWAMKVGDQDVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLKVSEIIGQVWRAAREIGLQKETGRRPITNVVMMGMGEPLLNMKNLIPALEIMLDDLGFGLSKRRVTVSTSGVVSGLDQMTGKIDVALAISLHAPNDELRSQIMPINDRWDIQDFLASVRRYIASSNANRGKVTVEYVLLDHVNDDMDHARELAELMKDTPCKINLIPFNPYPGSPYKKPSNSRIDRFQKTLMQYEHTVTVRKTRGDDIDAACGQLVGDVIDRTKRTAALKAARGAETIDVKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFD1_CHAGB
Sequence: MSLSKVKHIVLVLSGKGGVGKSSVTTQLALSLSQAGHSVGVLDVDLTGPSIPRMFGIEDAKVTQAPGGWLPITVHEADPSTGIGSLRVMSLGFLLPRRGDAVVWRGPKKTAMVRQFLSDVFWDELDYLLIDTPPGTSDEHISLAETLLQKAHPEQLAGAVVVTTPQAVATADVRKELNFCTKTGIRVLGVVENMSGFVCPNCSECTNIFMSGGGEVMAKDFNVRFLGRIPIDPQFLVLIETGKSPRYPEGTSVNGQDISSATQVAANGDETRDSRLLVYKYKSCSLAPIFGPITADIIADVTR
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor CFD1, Cytosolic Fe-S cluster-deficient protein 1.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPB_BACHK
Sequence: MDRTEQKSIIEGLLFVSGDEGIYPEQIAKVLEIEGNEVIDILEEMQKECEGAHRGLQIVQYAKVYRFATKKEHASYYQKLIEIPTAASLSQAALETLAIVAYRQPITRTEMEEIRGVKTDKALQTLVSHLLIKEMGRAEGPGRPILYGTTKEFLDTFGLKTLDDLPPLSEENEQMNEADLFFGSLQEISK
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: TRM82_YEAST
Sequence: MSVIHPLQNLLTSRDGSLVFAIIKNCILSFKYQSPNHWEFAGKWSDDFDKIQESRNTTAKEQQGQSSENENENKKLKSNKGDSIKRTAAKVPSPGLGAPPIYSYIRNLRLTSDESRLIACADSDKSLLVFDVDKTSKNVLKLRKRFCFSKRPNAISIAEDDTTVIIADKFGDVYSIDINSIPEEKFTQEPILGHVSMLTDVHLIKDSDGHQFIITSDRDEHIKISHYPQCFIVDKWLFGHKHFVSSICCGKDYLLLSAGGDDKIFAWDWKTGKNLSTFDYNSLIKPYLNDQHLAPPRFQNENNDIIEFAVSKIIKSKNLPFVAFFVEATKCIIILEMSEKQKGDLALKQIITFPYNVISLSAHNDEFQVTLDNKESSGVQKNFAKFIEYNLNENSFVVNNEKSNEFDSAIIQSVQGDSNLVTKKEEIYPLYNVSSLRKHGEHYS
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82, Transfer RNA methyltransferase 82.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
Protein: RS4_ALTMD
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKIDTAPGQHGARRGRLSDYGVQLREKQKVRRMYGVLEKQFRNYYKEAARLKGNTGENLLQLLEQRLDNVVYRMGFASTRAEARQLVSHKAIMVNGQVVNIPSFNVSAEDVVSVREKAKKQARIVAALELADQREKPTWIEVDSSKMEGTFKRVPERTDLSAEINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.