PharMolix/UniProtQA huggingface dataset:
Protein: DXR_DESRM
Sequence: MMKQISILGSTGSIGRQTLEVVNSFPEELNVVALAAGRNRELFLEQCKAYKPLLVSLQLEEDALWLKEHLIKEKLRPEIRYGLDGLVAVATCHEAVVVVTALSGAIGLVPTCAAIKASKKIALANKETLVAAGQYVTKLAEEYKVEILPVDSEHSAIWQCLHGENRSAIRKIQLTASGGPFRQLNRQELENVTPEMALKHPNWSMGQKITIDSATLMNKGLEVIEAKWLFGVDYDDINVVVHPQSVIHSMVEYGDGSLLAHLGMPDMRIPIQYALSYPERWFNHLPKLNLTELKGLTFEEPDTNRFPSLSLAYQAGKIGGTAPAVLNAANEVAVHAFLAGQIKFMQIPSIVKRTLNEHQFQGSPVLEEILEIDGWAREEANKIIRNC
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: CAS1B_MOOTA
Sequence: MRTYYIFSSGRLRRMDNTLALELETERRVVPVEDIDHIYCFSELDLNTRLLDFLAQKQICLHFFNYYGHYSGSFIPRESQLSGFLLVRQVEHYLDQAKRLELARTFVEGALHNIRRNLEKREYDDICSKLDEIREGIGKTASIEELMSLEAHARKAYYDTWEEITGWEFGSRSKRPPANALNALISFGNAMMYTVVLKEIYRTALNPTISYLHEPSERRYSLALDVAEIFKPVFVDRLIFRLINLNMLKETHFDTNVNFVYLTEGGRKVFVKEFEETLEKTILHRKLKRNIRYKSLVRLDLYKLIKHLLGEEKYSPMKVWW
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endonuclease Cas1 2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: CARB_CAMJE
Sequence: MPKRTDIKSILLIGSGPIVIGQACEFDYSGTQAAKTLKELGYRVVLINSNPATIMTDPEFADATYIEPITKESILSIIKKEKIDAILPTMGGQVALNVAMEVYESGLLGDVKFLGANPEAIKKGEDRQVFKECMKKIGMDLPKSMYAYNYDEALKAVDEIDFPLMIRASYTLGGAGSGVVYNMDEFKELTNTALALSPIHEILIEESLLGWKEYEMEVIRDRADNCIIVCSIENIDPMGVHTGDSITIAPALTLTDKEYQVMRNASFAILREIGVDTGGSNVQFAINPKNGRMIVIEMNPRVSRSSALASKATGYPIAKVATLLAVGFSLDEIKNDITGTPASFEPVIDYIVTKIPRFTFEKFPGANTTLGTAMKSVGEVMAIGRTFKESIQKALCSLERSLSGFDRVKFEDRNDLVFKIRNANEKRLLYVAQAFREGFSVEELYELCKIDPWFLTQIKEIVDFEEQIDMDILNNKALLRKAKTMGFSDKMIALLVNLKDNLELSQNDIYYVRMKQKIIAEFSEVDTCAGEFEALTPYLYSSINVSELTQSKNDAKDKKEKKVMIIGGGPNRIGQGIEFDYACVHASFALKDMGIKTIMYNCNPETVSTDYDTSDILYFEPIDFEHLRAVIEREKPDGVIVHFGGQTPLKFAKRLSAFGAKIIGTSARVIDMAEDRKKFAEFITKLGINQPKNSTATSVEEAVLKASDIGYPVLVRPSYVLGGRAMRVVNDEAELRLYMQEAVDVSDKSPVLIDQFLDNATEIDVDAICDGKDVYVAGIMEHIEEAGIHSGDSACSLPPCNIDEKMQEFIAQKTADIALNLGVVGLLNIQFALHNNELYMIEVNPRASRTIPFVSKATGIPLAKVATRVMWQGNLKEALKFYDTFKVVNFDTKILRPKTPKYMSVKEAVFPFAKLSGSDLELGPEMRSTGEVMGISKDFANSYAKSQIASFNHLPEQGVVFISLKDKDKKYTKKIAAEYVKLGFKLMATGGTCKEILESGFECELVHKISEGRPNVEDKLKNGEIHLVINTSDSHSFKGDTKKIRENIIRFKIPYFTNLRSALAGAKSIKAIQSKSCLDVKSLQEWLKS
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: KDSB_RHORT
Sequence: MTQSPSLAAAAPIVVIPARMASTRLPGKPLADIHGVPMIVQVWRRAMEAGIGPVLVAAAEDEIAQAVRAAGGNAVLTDPDLPSGSDRVWQAVERFDPAGRHAVVVNVQGDLPTLDPGLIIRAVETVLAEPDIALSTLICEITREEERTNPNVVKAVVGLAEGQTRGRALYFSRATVPHGPGPHYHHIGLYAYRRTTLGAFVSLPPGVLERREKLEQLRALENHMRIEAALVDTVPLGVDTAEDLERARALLG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_THET2
Sequence: MSKLASPQSVRALLERHGLFADKRFGQNFLVSEVHLRRIVEAARPFTGPVFEVGPGLGALTRALLEAGAEVTAIEKDLRLRPVLEETLSGLPVRLVFQDALLYPWEEVPQGSLLVANLPYHIATPLVTRLLKTGRFARLVFLVQKEVAERMTARPKTPAYGVLTLRVAHHAVAERLFDLPPGAFFPPPKVWSSLVRLTPTGAPDDPGLFRLVEAAFGKRRKTLLNALAAAGYPKARVEEALRALGLPPRVRAEELDLEAFRRLREGLEGAV
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_ECOSM
Sequence: MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGTQLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHDLSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDKSIHTIDATQPLESVMDAIRTTVTNWVKELDA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: H11_RAT
Sequence: MSETAPVPQPASVAPEKPAATKKTRKPAKAAVPRKKPAGPSVSELIVQAVSSSKERSGVSLAALKKSLAAAGYDVEKNNSRIKLGLKSLVNKGTLVQTKGTGAAGSFKLNKKAESKASTTKVTVKAKASGAAKKPKKTAGAAAKKTVKTPKKPKKPAVSKKTSSKSPKKPKVVKAKKVAKSPAKAKAVKPKAAKVKVTKPKTPAKPKKAAPKKK
What is the function of this protein?
H1 histones bind to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber.  H1 histones are necessary for the condensation of nucleosome chains into higher-order structured fibers.  Acts also as a regulator of individual gene transcription through chromatin remodeling (By similarity).
What are the official names of this protein?
Histone H1.1, Histone H1a.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Mainly localizes in euchromatin.
Protein: EFTS_STRU0
Sequence: MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAIELLREKGMAKAAKKADRVAAEGLTGVYVSGNYAAVVEVNAETDFVAKNAQFVELVNDTAKTIAEGKPANNEEALNLIMPSGETLAAAYVNATATIGEKISFRRFSLLEKTDEQHFGAYQHNGGRIGVISVIEGGDDALAKQVSMHIAAMKPTVLSYTELDPQFVKDELAKLNHNIELDNESRAMVDKAPLPFLQYGSKAQLSEDVIAKAEEDIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFESEVAATMAAALNN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_CAUSK
Sequence: MPALFVTGTGTDIGKTHVSCALIRALKVRGAVVDAFKPVVSGFDPKDAAGSDPARLAIALGDPSAVFRIAPRRYRAPLSPNIAAQLEGETLVLDDMVIDAVARAAELRDGLLLVEGAGGVMSPLTDTQTNLDMIVALGAPVLLVAGSYLGTISHVLTALVALRAAKVRVAAVVISESLDAPDLDQTAQALAPFLDGAPLFLAPRGESWDAGALADHLLAAVAPNAFGGTP
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_PROA2
Sequence: MRYTSAAIESLIEEFAKLPGIGRKTAQRLAMHILHQHTDEVEKFASALIDVKQKVIHCRVCQNVTDIGADPCAICCAKGRDRSVICVVETPSDVLAFEKTGQYRGLYHVLHGVISPLDGIGPDDIGVKELLSRLSPDDGPRVSELIMALNPTVEGETTVLYISKLLKPLGVQVTKIARGIPVGAELEFVDEATLSRALEGRSAL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PERX_TOBAC
Sequence: MSFLRFVGAILFLVAIFGASNAQLSATFYDTTCPNVTSIVRGVMDQRQRTDARAGAKIIRLHFHDCFVNGCDGSILLDTDGTQTEKDAPANVGAGGFDIVDDIKTALENVCPGVVSCADILALASEIGVVLAKGPSWQVLFGRKDSLTANRSGANSDIPSPFETLAVMIPQFTNKGMDLTDLVALSGAHTFGRARCGTFEQRLFNFNGSGNPDLTVDATFLQTLQGICPQGGNNGNTFTNLDISTPNDFDNDYFTNLQSNQGLLQTDQELFSTSGSATIAIVNRYAGSQTQFFDDFVSSMIKLGNISPLTGTNGQIRTDCKRVN
What is the function of this protein?
Plays an integral role in secondary cell wall biosynthesis by the polymerization of cinnamyl alcohols into lignin and by forming rigid cross-links between cellulose, pectin, hydroxy-proline-rich glycoproteins, and lignin.
What are the official names of this protein?
Lignin-forming anionic peroxidase, TOPA.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SECA_BRASB
Sequence: MIGALARKLFGSANDRRVKGYQARVNAINALEPELAKLTDEQLKARTAEFKAQLAEGKTLDDILVPAFATVREASKRTLGQRHFDVQLIGGMVLHEGDIAEMKTGEGKTLVATLAVYLNALAGKGVHVVTVNDYLARRDAGWMSQIYGFLGLTTGVIVHGLDDAERKLAYACDITYGTNNEYGFDYLRDNMKYRLEDMVQRGHYFAIVDEVDSILIDEARTPLIISGPLDDRSDFYNTIDTFVPKLDKSDYDVDEKQRTVTLTEAGMEKIETLLRDAGQLKGESLYDVENVSVVHHINQALRAHTLFTRDKDYIVRDGEVVIIDEFTGRMMPGRRYSEGLHQALEAKEHVQVQPENQTLASITFQNYFRMYEKLAGMTGTAATEADELFDIYKLEVVEIPTNLPVARLDEDDEVYRTQQEKYAAILAEIERANSRLQPVLVGTASIEKSEVLAAYLKQHGYKQIDFGSERALDKLYAAARAGKPAKLFAVLNARFHEQEAYIVAEAGVPGAITIATNMAGRGTDIKLGGSLEMRIQQETAGITDETEKAAKIEQIKADIARFREIVLKAEETVEIEPAKGSKPAKTVVKPGGLYIIGSERHESRRIDNQLRGRSGRQGDPGRSKFFLSLEDDLMRIFGSDRLDSMLTRLGLKEGEAIIHPWINKALEKAQQKVEARNFDIRKNLLKFDNVQNDQRKVIFDQRVELMQDESVAETIADMRHAFIDDLVSKHVPEHAYAEQWDVAGLKEELKRVLDIELPVDEWAKEEGIADEELLKRIETHADERMAAKVGQWGPDVMRYVEKTILLQTLDHLWREHLVMLDHLRQVIGLRGYGQRDPLQEYKSEAFTLFEAMIAHLREAVTAQLMRVEIVPPEEQQPVLPPMQAHHANPTTGEDEMAFANVSLVPSSGAAPVPAEARNPNDPSTWGKVGRNEDCPCGSGKKYKHCHGRYA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: Y2951_MYCBO
Sequence: MDLGGVRRRISLMARQHGPTAQRHVASPMTVDIARLGRRPGAMFELHDTVHSPARIGLELIAIDQGALLDLDLRVESVSEGVLVTGTVAAPTVGECARCLSPVRGRVQVALTELFAYPDSATDETTEEDEVGRVVDETIDLEQPIIDAVGLELPFSPVCRPDCPGLCPQCGVPLASEPGHRHEQIDPRWAKLVEMLGPESDTLRGER
What are the official names of this protein?
Uncharacterized protein Mb2951c.
What is the protein family that this protein belongs to?
To M.leprae ML1660.
Protein: EA10_LAMBD
Sequence: MSNIKKYIIDYDWKASIEIEIDHDVMTEEKLHQINNFWSDSEYRLNKHGSVLNAVLIMLAQHALLIAISSDLNAYGVVCEFDWNDGNGQEGWPPMDGSEGIRITDIDTSGIFDSDDMTIKAA
What is the function of this protein?
The ea10 gene protein is believed to be involved in the production of the Tro phenotype.  This phenotype is expressed when phages that possess a mutant cro gene and a thermolabile cI repressor gene are unable to propagate at restrictive temperatures.  This inability is correlated with the shutoff of host macromolecular synthesis.
What are the official names of this protein?
Protein ea10.
Protein: ARGC_PSECP
Sequence: MTISVAVSGASGYAGGEVLRILAGHPDVTIGAITAHSNAGSRLGELQPHLHGLASRILEDTTVENLSGHDVVFLALPHGASAEIAAQLPEGTVVIDAGADHRLEDPAAWEKFYGSAHAGTWPYGLPELPGQREALKGATRIAVPGCYPTSALLALTPGFAANLLEPDDVVIVSASGTSGAGKAAKVNLIGAEVMGSMSPYGVGGGHRHTPEIEQGLSNAAGERVTVSFTPTLAPMSRGILTTATAKVKAGTTAEQLRQAWADAYDDEPFVHLLPEGQWPGTKSVQGSNHAAMQLAFDPHTGRVVVTCVIDNLTKGTAGGAVQSMNIALGLPETAGLNLQGVAP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3371_MYCTU
Sequence: MAQLTALDAGFLKSRDPERHPGLAIGAVAVVNGAAPSYDQLKTVLTERIKSIPRCTQVLATEWIDYPGFDLTQHVRRVALPRPGDEAELFRAIALALERPLDPDRPLWECWIIEGLNGNRWAILIKIHHCMAGAMSAAHLLARLCDDADGSAFANNVDIKQIPPYGDARSWAETLWRMSVSIAGAVCTAAARAVSWPAVTSPAGPVTTRRRYQAVRVPRDAVDAVCHKFGVTANDVALAAITEGFRTVLLHRGQQPRADSLRTLEKTDGSSAMLPYLPVEYDDPVRRLRTVHNRSQQSGRRQPDSLSDYTPLMLCAKMIHALARLPQQGIVTLATSAPRPRHQLRLMGQKMDQVLPIPPTALQLSTGIAVLSYGDELVFGITADYDAASEMQQLVNGIELGVARLVALSDDSVLLFTKDRRKRSSRALPSAARRGRPSVPTARARH
What is the function of this protein?
Upon expression in E. coli functions weakly as a triacylglycerol synthase, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA.  Has no wax synthase activity to produce wax esters.
What are the official names of this protein?
Putative diacyglycerol O-acyltransferase Rv3371, Putative triacylglycerol synthase Rv3371.
What is the protein family that this protein belongs to?
Belongs to the long-chain O-acyltransferase family.
Protein: YACG_METEP
Sequence: MSQSVKRTAADKPLAPCPICGKPARTETKPFCSPRCADIDLGRWLGERYVIPGPEEEEMSYPPRSDDENRSR
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: NFYC_HUMAN
Sequence: MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQGQRNASQGKPRRCLKETLQITQTEVQQGQQQFSQFTDGQRNSVQQARVSELTGEAEPREVKATGNSTPCTSSLPTTHPPSHRAGASCVCCSQPQQSSTSPPPSDALQWVVVEVSGTPNQLETHRELHAPLPGMTSLSPLHPSQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
What is the function of this protein?
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.  NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
What are the official names of this protein?
Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC, Transactivator HSM-1/2.
What is the protein family that this protein belongs to?
Belongs to the NFYC/HAP5 subunit family.
Protein: RL5_BACAC
Sequence: MNRLKEKFQKEITPALVSKFNYKSVMQVPKIEKIVINTGVGDAVSNSKTLDNAVEELTQITGQKPVVTRAKKSIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSKKSFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTAKTDEEARELLTQFGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SODC_HORSE
Sequence: MALKAVCVLKGDGPVHGVIHFEQQQEGGPVVLKGFIEGLTKGDHGFHVHEFGDNTQGCTTAGAHFNPLSKKHGGPKDEERHVGDLGNVTADENGKADVDMKDSVISLSGKHSIIGRTMVVHEKQDDLGKGGNEESTKTGNAGSRLACGVIGIAP
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MIAA_PAEAT
Sequence: MSFTRQEPPRPVIAVVGPTGSGKSDLGVNLALALDGEVINADALQFYRGMDIGTAKITVEERRGVPHHLLDSMDVTQEASVADFQDECRAAINDIHSRGKRAILVGGSGLYVRAALDVLEFPGTDPTLRKELEEECENNGLAPLRARLEEVDPVSAARLGDARRVIRALEVHGLTGRPFSSFMPQREYFQPALQIGLEVDREQLRERLAVRVHRMVEGGLQQEVERLDAVGLRSGKTASRALGYAQFLKVLDGEMTADTAAEETIVATRQFARRQLTWFRADPRITWLGWQDPELVDKAVKVVNAAST
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PFMAH_PESFW
Sequence: MLMISNCSRDLLQRHFSNYHDPSASEAPVAGAGPSVAGKTPIACLNCSQAKTGCNKEVPCQRCQDKGLHCVQRYARRTSKLAARSQAAATAAAAQASRVAQVTPVTVQQSLPNVSVSIEPSQTLSQIQPPLVHEGGASVTMDPAILEMPLMNSFMKQQDPEVHDGSSPANSITFPLPIHLKAESPRQRTASVDLNFNNMNSEPSPPSIEPMEDQSWVNSLMSNDPNFGPGNMFSSTYDLGYQLGPSYADPTTDFSQMSQSMLQHDASMSSMEFAGSPSGVSPFGDLSTSNSEPSSSSWGSSHTRATSICSAHCLYDQSGEFDVTSNSAKQGLPISTDSDVILTEAAWPMARCTPPIYSGACPRTALGHLQRLEQKSSYQGARPFAWHTLERELSSLNWDNADLASVVPMNSQTRDSLMSISQRFHARALDIHRENDPGRDKSPLGSNCGPMSFLNLPSSKVLEFFMKSYVRSLTSFYSLVSEGRIDPNQMHRNDPASIILMLLMIAQGASAVDSEDARILSMGLIETCRISLLDIIDKNVEMSADPTALRAALLFAHLGAWSGDKWLMDIAMGQRGMYISMLKHAGMLTAQPPICPVLDGDQGQKNSWRLWLQVETKNRLVYDWVMVDQELSLFHDTDPQLDVSELRASLPCSEKLWKSSTVEQWADAVQCYLSKGNPHPLTPPSLYHLYREFLEQKLVDGRVGLTAHQLRLLLHPIQKMLCQQRQTLTCFSDMFVPDQPGHVSFSKAYVMRQVEVVRSLLSRWHDLAMRCLNMNPDCTIMRTNMVLYHLISLNAVTNFPEIESFARQERYDGSYWGSRHQRCIYNRQQAVHDCGQVFSILRNLPTDRLPTWWSAAIYRATMILWADSALQSQSQAHASLSPPEATEGQYAMNAPQDFNHTLDYNVIPYVTRSDGTPFHLDRHSEVLDYAICAIDQGASSRLGEGIKRKLIALGNNWH
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment forming a dark layer in the conidial wall that protects the conidia from UV radiations (PubMed:28517364).  The 2 transcription factors present in the cluster, PfmaF and PfmaH, coordinately regulate DHN-melanin production (PubMed:31116900).  PfmaH acts as a pathway specific regulator to mediate the expression of Pfma cluster genes including PfmaJ, leading to DHN-melanin production in conidia, and regulates the conidial formation (PubMed:31116900).
What are the official names of this protein?
Transcription factor PfmaH, Conidial pigment biosynthesis cluster protein H.
What are the subcellular locations of this protein?
Nucleus.
Protein: SELK_XENTR
Sequence: MVYIANGQVLDGQSRSPWRLSFLTDMFWGITDFIVMFFQSIIHPNVTRRGCQNSSSRTRFDDGRGPPGNPRRRMGRIDHNSGPNAPPMSGGGUGR
What is the function of this protein?
Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity).  Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity).  Required for cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (By similarity).  Required for palmitoylation (By similarity).
What are the official names of this protein?
Selenoprotein K, SelK.
What is the protein family that this protein belongs to?
Belongs to the selenoprotein K family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single- pass membrane protein. Note=Probably mainly localized in the ER.
Protein: RNH_FRATM
Sequence: MEIFKKKNRVIAYTDGACKGNPGIGGWGAILSYNGVDKEIYGSEKDTTNNRMELMAAIKTLQALKRKCDITIYTDSKYLQNGINEWLANWKANGWKTAAKKEVKNKDLWQELDSLTNKHNVTWGWVKGHSGNAGNEKADELANKAIAELIGK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_XENLA
Sequence: MAITRWLFSTNHKDIGTLYLVFGAWAGLVGTALSLLIRAELSQPGTLLGDDQIYNVIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGISSILGAINFITTTINMKPPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPVLYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGLLGFIVWAHHMFTVDLNVDTRAYFTSATMIIAIPTGVKVFSWLATMHGGTIKWDAPMLWALGFIFLFTVGGLTGIVLANSSLDIMLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFTGYTLHETWAKIHFGVMFAGVNLTFFPQHFLGLSAMPRRYSDYPDAYTLWNTVSSIGSLISLVAVIMMMFIIWEAFAAKREVTTYELTSTMLEWLQGCPTPYHTLKTSLVQINHQMIKS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.