PharMolix/UniProtQA huggingface dataset:
Protein: VQ5_ARATH
Sequence: MYQRPQNDYLRVNKRKSNYDQLNADSNSVPQLAQTQPRVQVYIIDKNDFKSLVQQLTSPQPCDRLPQNIPKHQDIRPEPINWTSSIPPSAMAVQEDPDVSLYMAYLQSLLEESSGSNGDQFEEPFDKYHSHMMAQSQPQDPTQSMPQSNGFEPFPSSWFNGSTQEMHGASSLQSTRVDYEYPLPLTPNFTFSSMTQHEVFGSDLDSIGPDEDLEFSYEIN
What is the function of this protein?
May function as negative regulator of plant defense.
What are the official names of this protein?
VQ motif-containing protein 5, AtVQ5.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPYL2_MOUSE
Sequence: MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG
What is the function of this protein?
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration.  Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.  May play a role in endocytosis.
What are the official names of this protein?
Dihydropyrimidinase-related protein 2, DRP-2, Unc-33-like phosphoprotein 2, ULIP-2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Membrane. Note=Tightly but non-covalently associated with membranes.
Protein: ILVD_ALKCK
Sequence: MRSNMIKKGIDRAPHRSLLRAAGVKEEDMDKPFIGVCNSYIDIIPGHMHLNKFAEVAKEAIIEAGGIPFEFNTIGVDDGIAMGHIGMRYSLPSREIICDAAETVINAHWFDGVFYIPNCDKITPGMLMAAVRTNVPAVFVSGGPMEAGRTKEGKSLSLVSVFEGVGAFSSGKMTREELLEIEQLACPTCGSCSGMFTANSMNSLMEMLGLALPGNGTLVATSTERHNLIKDAAKHLINLIEKDIRPRDIVTEETIDDAFALDMAMGGSTNTVLHTLAIANEAEIDYDLTRINEVAERVPYLCKISPASDYSMDDVHKAGGVAAIMKELIEMGAVKGDRITITGKSLYENVAHAQITNTDVIRTKETAYSPVGGLSILYGNLAPDGAVIKVGAVDPSIKTFTGEAIVFNSQEEAQEQINNGAVKEGQVVVIRYEGPKGGPGMPEMLAPTSAIQGRGLGTKVALITDGRFSGASRGISIGHISPEAAEGGPIAFVENGDMIKIDLIERTIEWEISEEELAKRREGWTEPEPKVKKGYLARYSKLVTSANTGGVMKI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: ACCD_HELMI
Sequence: MDGLWVKCKQCQQILLTKELEKNLKVCRCGYHFRMTAQERIVMLVDENSFIEWDRELVSKDPLQFPGYAQKIQKCQIETSMSEAITTGQGRICDIPVVLGVMDPRFIMASMGAVVGEKIVRAAERALKLRLPLVLFSASGGARMQEGVLSLMQMARTSAALTRLSKAGLPFFSVLTDPTTGGVTASFAMLGDLIIAEPGALIGFTGPRVIEQTIRQKLPEGFQRSEFLQKHGMVDIIIERPKMREQLAALLALHCGNSLEGVES
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP5H_RAT
Sequence: MAGRKLALKTIDWVSFVEIMPQNQKAIGNALKSWNETFHTRLASLSEKPPAIDWAYYRANVDKPGLVDDFKNKYNALKIPVPEDKYTALVDAEEKEDVKNCAQFVTGSQARVREYEKQLEKIKNMIPFDQMTIDDLNEVFPETKLDKRKYPYWPHQPIENL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
What are the official names of this protein?
ATP synthase subunit d, mitochondrial, ATPase subunit d, ATP synthase peripheral stalk subunit d.
What is the protein family that this protein belongs to?
Belongs to the ATPase d subunit family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: UGPC_RHOPS
Sequence: MANVVLRNVRKTYPGGFEAIKGVDLEVGDGQFCVLVGPSGCGKSTLLRMVAGLETITAGEIDIGGRVVNDVEPADRDIAMVFQNYALYPHMSVYNNMAYGLRNRGMAKPEIEARVQEAARILEIGAMLDRKPRQLSGGQRQRVAMGRAIVRQPKVFLFDEPLSNLDAKLRVAMRVEIRKLQRRLSTTAIYVTHDQLEAMTLADILVVMNAGQVEQIGSPLDVYAKPATTFVASFIGAPPMNLIPLDAEGVRARFGGAVTEAGVLGVRPEDLAISSEPPAPGGLTLDLAVEAIERVGPETFVYGTRSPGGDLAAISSKPGELPPDEIIIRIPGQEAPAIGQRISVVALRHNLHLFSADGRRRIAV
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HDG7_ARATH
Sequence: MNGDLEVDMSRGDFNPSFFLGKLKDDEFESRSLSDDSFDAMSGDEDKQEQRPKKKKRKTKYHRHTSYQIQELESFFKECPHPNEKQRLELGKKLTLESKQIKFWFQNRRTQMKTQLERHENVILKQENEKLRLENSFLKESMRGSLCIDCGGAVIPGEVSFEQHQLRIENAKLKEELDRICALANRFIGGSISLEQPSNGGIGSQHLPIGHCVSGGTSLMFMDLAMEAMDELLKLAELETSLWSSKSEKGSMNHFPGSRETGLVLINSLALVETLMDTNKWAEMFECIVAVASTLEVISNGSDGSRNGSILLMQAEFQVMSPLVPIKQKKFLRYCKQHGDGLWAVVDVSYDINRGNENLKSYGGSKMFPSGCIIQDIGNGCSKVTWIEHSEYEESHTHSLYQPLLSSSVGLGATKWLATLQRQCESFTMLLSSEDHTGLSHAGTKSILKLAQRMKLNFYSGITASCIHKWEKLLAENVGQDTRILTRKSLEPSGIVLSAATSLWLPVTQQRLFEFLCDGKCRNQWDILSNGASMENTLLVPKGQQEGSCVSLLRAAGNDQNESSMLILQETWNDVSGALVVYAPVDIPSMNTVMSGGDSAYVALLPSGFSILPDGSSSSSDQFDTDGGLVNQESKGCLLTVGFQILVNSLPTAKLNVESVETVNNLIACTIHKIRAALRIPA
What is the function of this protein?
Probable transcription factor that binds to the DNA sequence 5'-GCATTAAATGC-3' (PubMed:16778018).  Seems to promote cell differentiation (PubMed:25564655).
What are the official names of this protein?
Homeobox-leucine zipper protein HDG7, HD-ZIP protein HDG7, Homeodomain GLABRA 2-like protein 7, Homeodomain transcription factor HDG7, Protein HOMEODOMAIN GLABROUS 7.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class IV subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCIC_ECOL6
Sequence: MSITAQSVYRDTGNFFRNQFMTILLISLLCAFITVVLGHVFSPSDAQLAQLNDGVPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVILIIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLALAPVMLVQDKMGVFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEIGAVLANTLSNLISAVLLIYLFRLYMLIRQ
What are the official names of this protein?
UPF0259 membrane protein YciC.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HPCD_METS5
Sequence: MEFETIETKKEGNLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKGKAFCAGADITQFNQLTPAEAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALACDIRIAAEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVNRVVPLANLEQETRKLAEKIAKKSPISLALIKEVVNRGLDSPLLSGLALESVGWGVVFSTEDKKEGVSAFLEKREPTFKGK
What is the function of this protein?
Plays a role in autotrophic carbon fixation via the 3-hydroxypropionate/4-hydroxybutyrate cycle.  Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl-CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crotonyl-CoA.  Inactive towards (R)-3-hydroxybutyryl-CoA.
What are the official names of this protein?
3-hydroxypropionyl-coenzyme A dehydratase, 3-hydroxypropionyl-CoA dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: GLNA_MACFA
Sequence: MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEWNFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCESFQVQFEGPAETNLRHTCKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHYRACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCLLNETGDEPFQYKN
What is the function of this protein?
Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity).  Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity).  Essential for proliferation of fetal skin fibroblasts.  Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation.  May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ (By similarity).  Plays a role in ribosomal 40S subunit biogenesis (By similarity).
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Palmitoyltransferase GLUL.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Microsome. Mitochondrion. Cell membrane; Lipid-anchor. Note=Mainly localizes in the cytosol, with a fraction associated with the cell membrane.
Protein: DEFTR_TRIIM
Sequence: MQFTKLATVLIVSLMGSAAIAAPSVDNAPAVAAEEVAAAPAENLEKRGFGCPLNERECHSHCQSIGRKFGYCGGTLRLTCICGKE
What is the function of this protein?
Antimicrobial peptide with broad-spectrum activity against Gram-positive bacteria, Gram-negative bacteria, and fungi.  Also inhibits clinical isolates, including methicillin-resistant S. aureus (MRSA) (MIC=32 uM), K. pneumoniae, C. albicans and C. parapsilosis.  Displays minimal inhibitory concentration (MIC) values similar to minimal bactericidal concentrations (MBC), suggesting a disruptive mechanism mode of action associated with membrane lysis.  In vitro, shows hemolytic activity against human red blood cells.
What are the official names of this protein?
Fungal defensin triintsin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: COX4_BACP3
Sequence: MANQTNSGNERVDLAYRRRKNAEEMRHQMIAFVLMILLTLIAFAAVGYEEFSHWFVVPFILLLAAVQVAFQLYYFMHMSHKGHEFPAMFIYGGVAVMLLLVWAFTTVVWW
What are the official names of this protein?
Cytochrome c oxidase subunit 4B, Cytochrome aa3 subunit 4B, Cytochrome c oxidase polypeptide IVB.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase bacterial subunit 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FDHE_SHEB8
Sequence: MSHTAEIPLVPGSESPLELKPLKAADPQAVYHRRAHRLLSLAKDSPLADYFELCRRLVSIQAKLAEEADFGQLLAWGKDEATPLSLLGSEADSYWQGLLQQLLSDLLPQVDESIARVMRLLMQQSPEQLSSWGRSLRQGHVSEVPAHFSLFIWAAMGVYWSHWAPMVIKRMDQRKVAQQSMCPVCGCHPVASVIVDQPRAGLRYLHCSLCESEWHYIRAHCTSCGQDKEMTIWSLDDAQAQVRIESCDECHGYTKMMFVENSPSMDVAADDLATLMLDSELNAKGFGATTLNPLLMAHETT
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_LIMF3
Sequence: MASNKIIGIDLGTTNSAVAVMEGNEPKIITNPEGGRTTPSVVSFKNGEVQVGEVAKRQAITNPNTVKSIKSHMGEAGYTVDIEGKKYTPQEISAMILQYIKKYAEDYIGDTVTEAVITVPAYFNDAQRQATKDAGKIAGLDVKRIINEPTASSLAYGLDKKDRDEKILVYDLGGGTFDVSILELGDGVFQVLSTNGDTHLGGDDFDQKIMDWLIDGFKQENGIDLSQDKMALQRLKDAAEKAKKDVSGVQEAQISLPFITSGDNGPLHLEKTLTRAQFNQLTNDLVERTKQPVLNALKDAELSFSDIDEVILNGGSTRIPAVQEMVKSLTGKEPNHSINPDEAVALGAAIQGGVLTGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGNFQLTDIPPAPRGVPQIKVTFDIDKNGIVNVSAEDQGTHKKQNITIKSNSGLSDEEIERMKKDAEANAEADKKKKEEADLRNETDQLLFQTDKTLEELKGKVSDDEIKKAQDAKDALQKAKDDNNLEDMKAKKDDLNKIVQDLTVKLYQQAQQENQANGGQPTGDQGDGKKDDDNTVDGDFEEVNPDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HSP60_YEAST
Sequence: MLRSSVVRSRATLRPLLRRAYSSHKELKFGVEGRASLLKGVETLAEAVAATLGPKGRNVLIEQPFGPPKITKDGVTVAKSIVLKDKFENMGAKLLQEVASKTNEAAGDGTTSATVLGRAIFTESVKNVAAGCNPMDLRRGSQVAVEKVIEFLSANKKEITTSEEIAQVATISANGDSHVGKLLASAMEKVGKEGVITIREGRTLEDELEVTEGMRFDRGFISPYFITDPKSSKVEFEKPLLLLSEKKISSIQDILPALEISNQSRRPLLIIAEDVDGEALAACILNKLRGQVKVCAVKAPGFGDNRKNTIGDIAVLTGGTVFTEELDLKPEQCTIENLGSCDSITVTKEDTVILNGSGPKEAIQERIEQIKGSIDITTTNSYEKEKLQERLAKLSGGVAVIRVGGASEVEVGEKKDRYDDALNATRAAVEEGILPGGGTALVKASRVLDEVVVDNFDQKLGVDIIRKAITRPAKQIIENAGEEGSVIIGKLIDEYGDDFAKGYDASKSEYTDMLATGIIDPFKVVRSGLVDASGVASLLATTEVAIVDAPEPPAAAGAGGMPGGMPGMPGMM
What is the function of this protein?
May participate in assembly and/or disassembly of proteins imported into the mitochondrion.  HSP60 are ATPases and have affinity for unfolded proteins.
What are the official names of this protein?
Heat shock protein 60, mitochondrial, CPN60, P66, Stimulator factor I 66 kDa component.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GFCB_ECOLI
Sequence: MRPLILSIFALFLAGCTHSQQSMVDTFRASLFDNQDITVADQQIQALPYSTMYLRLNEGQRIFVVLGYIEQEQSKWLSQDNAMLVTHNGRLLKTVKLNNNLLEVTNSGQDPLRNALAIKDGSRWTRDILWSEDNHFRSATLSSTFSFAGLETLNIAGRNVLCNVWQEEVTSTRPEKQWQNTFWVDSATGQVRQSRQMLGAGVIPVEMTFLKPAP
What are the official names of this protein?
Uncharacterized lipoprotein GfcB, Group 4 capsule protein B homolog.
What is the protein family that this protein belongs to?
To E.coli YjbF.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL331_STRGG
Sequence: MARNEVRPVIKLRSTAGTGYTYVTRKNRRNDPDRMVLRKYDPVARRHVDFREER
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RAPA_SALCH
Sequence: MPFTLGQRWISDTESELGLGTIVAMDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHEGWQLHIDEVKEENGLLVYVGTRLDTEETNVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPYSGLRGQRTNLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYTEAQHDAYNPFETEQLVICSLDFARRNKQRLEHLCDAEWDLLVVDEAHHLVWSTDAPSREYMAIEQLAERVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQKNYRPVADAVAMLLAGNKLSNDELNRLGDLIGEQDIEPLLQAANSDRDDAQAARDELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTVKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKATTALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRAIYDSAYASLINYLAAPEETDGFDDLIKSCREQHEALKAQLEQGRDRLLEIHSNGGEKAQQLAQSIEEQDDDTNLIAFAMNLFDIVGINQDDRGDNLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELVYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLSAVNRHTGSKLVNAVQQDVHAILQLGETQIEKSARALIDNARREADEKLSGELSRLEALRAVNPNIRDDELAAIDSNRQQVLESLNQAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: RL22_CORA7
Sequence: MSDTITSASATARYVRVTPMKARRVIDLVRGKSVAEALAILKYAPQGAAEPVAKVVASAAANAENNFGLDPRTLVISEAYANEGPTMRRFQPRAQGRAFMIRKRTSHITVVVESQKEGAK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PEPT_YERP3
Sequence: MDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMATLPANVSWPVPTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNVPHGDIRIAFTPDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGVMVNALSLATRYHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKRVGKGLHRDCYIEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRISELTAKRAKEL
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPO_CANLF
Sequence: MELTELLLVVMLLLTARLDPCLPAPPACDPRLLNKMLRDSHVLHSRLSQCPDIYPLSTPVLLPAVDFSLGEWKTQKEQTKAQDVWGAVALLLDGVLAARGQLGPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPPQGRTTTHKDPNAIFLSFQQLLRGKVRFLLLVAGPTLCAKQSQPTTAVPTNTSLFLTLRKLPNRTSGLLETNSSISARTTGSGLLKRLQGFRAKIPGLLNQTSRSLNQTPGHLSRTHGPLNGTHGLLPGLSLTALGAPDIPPGTSDMDALPPNLWPRYSPSPIHPPPGQYTLFSPLPTSPTPQNPLQPPPPDPSATANSTSPLLIAAHPHFQNLSQEE
What is the function of this protein?
Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells.  It acts at a late stage of megakaryocyte development.  It may be the major physiological regulator of circulating platelets.
What are the official names of this protein?
Thrombopoietin, C-MPL ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF.
What is the protein family that this protein belongs to?
Belongs to the EPO/TPO family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASZ1_CALJA
Sequence: MAASALRGLAVAGGGESSESEDDGWEIGYLDRTSQKLKGQMLPIEEKKEKFKKALTTGDVSLVLELLDSGIISVDATFRYGWTPLMYAASVANAELVRVLLDRGANASFEKDKQTILITACSAHGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALLVASGAEVNTQDENGYTALTWAARQGHKSIVLKLLELGANKMLQTKDGKLPSEIAKRNKHHEIFNLLTFTLNPLEGKLQQLTKEETICKILTTDSDRENDHIFSSYAAFGDLEVFLHGLGLEHMTDLLKERDITLRQLLTMREDEFTKNGFTSKDQQKILAALKELEVEEIPFGELSEEAKLEISGDEFLNFLLKLNKQCGHLITAVQNIITELPVNSQKIALEWASPQNFTSVCEELVNNVEDLSEEVCNLKDLIQKLQNERENDPTHIPLREEVSTWNSRILKRTAITVCGFGFLFFICKITFQRK
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: HSP1_SMIBI
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHHNRRRTYRRSRRHSIRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RECR_SACD2
Sequence: MFSPLIDQLINSLRHLPGVGPKSAQRMALHLLERDREGAQNLSEVLAKAVEHVHRCQQCRTLTEQALCNICSNARRNRKELCIVETPADVIAIETSAVFSGYYFVLLGRLSPIDGIGPKEIGMDVLASRFAEGEIEEVIIATNPTIEGEATAHYISERAKAQGIKVSRIAHGIPIGGELEYVDGGTLAHAISRRQEI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: DDX6_XENLA
Sequence: MSTARTENPVLMGMSSQNGQLRGPLKPSAGPGGGGTQTQQINQLKNASTINSGSQQQAQSMSSIIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDCIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHIQMIVLDEADKLLSQDFMQIMEDIIMTLPKNRQILLYSATFPLSVQKFMTLHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSSIDKNLYVAEYHSESGEDKP
What is the function of this protein?
ATP-dependent RNA helicase that is an integral component of messenger ribonucleoprotein complexes (mRNPs), storage particles that mask maternal mRNAs from the translational apparatus during oocyte maturation.
What are the official names of this protein?
ATP-dependent RNA helicase ddx6, ATP-dependent RNA helicase p54, P54H, Xp54, DEAD box protein 6.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasm. Nucleus. Note=Mostly cytoplasmic. Upon cellular stress, relocalizes to stress granules.