PharMolix/UniProtQA huggingface dataset:
Protein: PSBD_TUPAK
Sequence: MTIAIGKSEQKRGLFDVADDWLRRDRFVFVGWSGLLLLPCAYFALGGWLTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPPNCMGHSLLLLWGPEAQSDFTRWCQLGGLWTFVALHGSFGLIGFMLRQFEIARAVKIRPYNAIAFSGPIAVFVSVFLIYPLGQAGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGILGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNNLLNEGIRAWMAAQDQPHERLVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL10_DEIRA
Sequence: MANEKNQQTLGSLKDSLQGIETFYVVDYQGLTAGQLTQLRKDIREKGGQLIVAKNTLLNLALQEGGRDFDDALKGPSALVLAQEDPAGVAKALSDAAGRNDRGIPTVKGGFVEGSKVDVAVVQRLASLGSKTTLQAELVGVLSAHLSNFVGILEAYREKLEGEGGSESA
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ACPS_CAUSK
Sequence: MIIGIGSDLCDIRRIEKTLERFGDRFTHKSFTEIERRRSERKPDRASSYAKRFAAKEACSKALGTGLKGGVHLSGMGVVNLPSGKPTMALTGGAAERLASMVPEGMTPVIHLSLTDDHPYAQAFVIIEAVAAT
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Z354A_RAT
Sequence: MAPEQREGASQVSVTFEDVAVLFTRDEWKKLDLSQRSLYREVMLENYSNLASMAGFLFTKPKVISLLQQGEDPWQVEKEGPRYFSLGLKCSHRTTKSTQTQDSSFQELIVRKSKRTFAFEPLNMKSENLFIHEGKLEEKWDKNTLTVERSHKNNEFSPKSHREKRSSECKKQISYLSNPPGITPDKRYKCSMCEKTFINTSSLRKHEKNHSGEKLFKCKECSKAFSQSSALIQHQITHTGEKPYVCKECGKAFTLSTSLYKHLRTHTVEKSYRCKECGKSFGQRSGLFIHQKIHARENPHRYNPGRKASASLSGCQRAHSRKKTYLCNECGNTFKSSSSLRYHQRIHTGEKPFRCSECGRAFSQSASLIQHERIHTGEKPYRCGECGKGFTSISRLNRHRIIHTGEKLYNCNECGKALSSHSTLIIHERIHTGEKPCKCKVCGKAFRQSSALIQHQRMHTGERPYKCNECGKTFRCNSSLSNHQRIHTGEKPYQCIECGMSFGQSSALIQHRRIHTGEKPFKCNTCGKTFRQSSSRIAHQRIHTGEKPYECNTCGKLFNYRSSLTNHYKIHVDEDP
What is the function of this protein?
It may play a role in renal development and may also be involved in the repair of the kidney after ischemia-reperfusion or folic acid administration.
What are the official names of this protein?
Zinc finger protein 354A, Kidney, ischemia, and developmentally-regulated protein 1, Renal transcription factor Kid-1, Transcription factor 17, TCF-17.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y411_STRGC
Sequence: MDLDKIGAETRQILQDVLDKASLDEGDVFVLGLSSSEVMGGHIGRNSSLEVGQVIVKTVLDILEEKGIFLAVQGCEHLNRALVVERSLAKKKDLEIVNVLPTLHAGGSGQLAAFQYMKDPVEVEFIVAQAGLDIGDTAIGMHVKHVQIPIRPKLKSVGAAHVTALASRPKLIGGSRAAYREDKIRKD
What are the official names of this protein?
UPF0340 protein SGO_0411.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: ZN474_MOUSE
Sequence: MESGNERISSQSQGTIHLSKEPTFLIQQATLPSDLHSTLLQETQCGGLTKNIKANTQKRRPGTVILSKRSSRIMSETQPRPPVIPSRRPGFRICYICGREFGSQSLAIHEPQCLEKWRTENSKLPKHLRRPEPSKPQPIGGTDSHSLQAANEEAFQSAQAQLLPCENCGRTFLPDRLLVHQRSCKPKGENPGPPSMGSSNVPTGLKKASSGIPARPRTLICYICGREFGTLSLPIHEPKCLEKWKIENDQLPRELRRPQPQKPQPLPAGQSSQEGASQAALVPCPNCGRTFAVDRLPVHQRSCKSQPSGPKTSNSNIERKGGPNPPTNSKQQRNMEAPNGDKVTGVI
What are the official names of this protein?
Zinc finger protein 474, Testis-specific zinc finger protein, TSZFP.
Protein: RSMH_RHIME
Sequence: MVTDQGGGTSEADGGPVRHIPVLLKEVLAALDPAPGKIILDGTFGAGGYASAILDAGADVVALDRDPTAIAAGQSMMHASGGRLKLVHSRFSDLAEHAPAQGLDGVVLDIGVSSMQIDEAERGFSFQKKGPLDMRMSAAGVSAADVVNRAKVSDLIRIFGFLGEEKQAGRIARAIEKRRAETPFETTRDLANLIETVTPRKAKDKIHPATRVFQALRIFVNDELGELAHALFAAERALKPGGRLVVVTFHSLEDRIVKTFFQDRSGKAGGSRHLPLVTARAATFTPVGKPMVAASEEEASRNPRARSAKLRAGVRTEAPSPGADLSIFNLPELASLARLGG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_ACTPJ
Sequence: MMTKEAPLIALVAGEISGDILGAGLINALKLHYPNARFIGVAGPRMIQAGCETLFDMEELAVMGLAEVVKYLPRLLKRRKQVIETMLAEKPDIFIGIDAPDFNLTVEEKLKASGIKAIHYVSPSVWAWRQNRVQKIARATNLVLAFLPFEKAFYDRFNVPCRFIGHTMADAIALKPNRSEACATLNLDETQRYLAILVGSRASEVRFLAEPFLKAAQILKQQYPDLQFLVPLVNDKRIAQFEQIKAQVAPELSVHILKGNARQAMIAAEASLLASGTAALEGMLCKSPMVVGYKMKAMTYWLAKRLVKTKYISLPNLLADEMLVPELIQDECNPENLAWYLGNYLADDADHRKQRNELKQRFTELHKLIQCDADAQAAQAVVDVLEANTSDQN
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: NADE_ECOUT
Sequence: MTLQQQIIKVLGAKPQINAEEEIRRSIDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRQETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNVPEQVARTIENWYLKTEHKRRPPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: Y353_BRUO2
Sequence: MRSTKVIHIVGCHAEGEVGDVIVGGVAPPPGETVWEQSRFIANDETLRNFVLNEPRGGVFRHVNLLVPPKDPRAQMGFIIMEPADTPPMSGSNSICVSTVLLDSGIIAMQEPVTHMVLEAPGGIIEVEAECRNGKAERISVRNVPSFADRLDAPLDITGLGTIMVDTAYGGDSFVIVDAAQIGMKIEPGQARELAEIGVKITKAANEQLGFRHPERDWRHISFCQITEPVTREGDVLTGVNTVAIRPAKLDRSPTGTGCSARMAVLHAKGQMKAGERFIGKSVLGTEFHCRLDKVLELGGKPAISPIISGRAWVTGTSQLMLDPSDPFPHGYRLSDTWPRDE
What are the official names of this protein?
Uncharacterized protein BOV_0353.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: NCAP_BUNYW
Sequence: MIELEFHDVAANTSSTFDPEVAYANFKRVHTTGLSYDHIRIFYIKGREIKTSLAKRSEWEVTLNLGGWKITVYNTNFPGNRNNPVPDDGLTLHRLSGFLARYLLEKMLKVSEPEKLIIKSKIINPLAEKNGITWNDGEEVYLSFFPGSEMFLGTFRFYPLAIGIYKVQRKEMEPKYLEKTMRQRYMGLEAATWTVSKLTEVQSALTVVSSLGWKKTNVSAAARDFLAKFGINM
What is the function of this protein?
Encapsidates the genome protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication.  Seems to participate in the nuclear relocalization of host PABP1, thereby inhibiting host cellular translation.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the orthobunyavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Note=Internal protein of virus particle.
Protein: GLYR1_DROME
Sequence: MSKNKKLSLSGGDTTEKFIYKPKDLIWAKMKGFTPWPGMIVDPPLDLLSQQRRANTKCVFFFGSRNFAWIEENNIKPFEGPWKEELAKVSKPAAFRHAMTDIEKYIDDPAEVDEQVNKSCGAPNHATEADFDKIRDGLDSEEIVGEEATADGNNGVVAHVVGSPDEGDGLDVEINADSSASPVTSPAVTTKAAGKRTPKAKSVAATSVKSTKGSAKSAQKRRTSAQQSPSGPSNAKRGKRDVSGEALQDADEASSTPTGRRRVETDALLASIAAKRAPNAIALLDRPVVTRPEAQVIDMSSRSNTLADRDIVPSEQTFGFLGLGMMGSTIVKDLIYTGHKVVVWNRTIDKCQPFAEAGAEVKDTPMDVVEAADVIFCCVSDPKGAKDLVFGNCGVLQLKDLNNKAYVEMSTIDPDTSLDIGEGIKQCNGRYLEAQIHGSRQEAAEGMLIILAGGDRSVFEECHSCFKTIAKNTFFLGNIGNACKVNLILQTILGVSLVGLAEALALADRFSISLNDIIDIFDLTSMKSPMLLAKGKEMAKGDFNPQQPLSHMQRDLRLVLNMAENLDQSMPVTSITNEVFKHTKRLGYSEHDSSAVFVRSRF
What is the function of this protein?
Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation and colocalizes with a subset of trimethylated 'Lys-36' histone H3 (H3K36me3)-enriched regions (PubMed:23295261, PubMed:29759984).  Binds DNA (in vitro) (PubMed:29759984).  Facilitates Pol II transcription through nucleosomes (PubMed:29759984).  Facilitates male-specific lethal (MSL) histone acetyltransferase complex targeting to active genes on the X chromosome (PubMed:23295261).  Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by nej (PubMed:29759984).  May have oxidoreductase activity (By similarity).
What are the official names of this protein?
Cytokine-like nuclear factor N-PAC, NPAC, Glyoxylate reductase 1 homolog, Nuclear protein NP60 homolog, Nucleosome-destabilizing factor, Putative oxidoreductase GLYR1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. NP60 subfamily.
What are the subcellular locations of this protein?
Chromosome. Note=Localization to open chromatin depends on H3K36 trimethylation by Set2.
Protein: GPMI_BRUMA
Sequence: MAEAKNRVCLVVIDGWGISNETKGNAILNAKTPVMDELCVMNSHPIQAHGLHVGLPEGLMGNSEVGHLNIGAGRVVYQDIVRINLAVKNKTLVENKHLKEAAERAIKGNGRMHLCGLVSDGGVHSHIDHLFALITALKQLKVPKLYIQFFGDGRDTSPTSGVGFLQQLIDFVNKEQYGEISTIVGRYYAMDRDKRWERIRVCYDALIGGVGEKTTIDKAIDVIKGRYAKDETDEFLKPIILSDEGRTKDGDTLIFFDYRADRMREITECMGMERYKDLNSNIKHPKNMQVIGMTQYKAEFTFPALFPPESHKNVLAEWLSVNGLTQFHCAETEKYAHVTFFFNGGVEKQFANEERCLVVSPKVATYDLEPPMSSAAVADKVIEQLHMKKHPFVMCNFAPPDMVGHTGVYEAAVKAVEATDIAIGRIYEACKKNDYILMVTADHGNAEKMMAPDGSKHTAHTCNLVPFTCSSMKYKFMDKLPDREMALCDVAPTVLKVMGVPLPSEMTGQPLVNEA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, iPGM, Cofactor-independent phosphoglycerate mutase homolog.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: HIS2_BACCQ
Sequence: MKNAFTLLFETIKERKRNPLSESYTNYLFLKGEDKILKKIGEECSEVIIASKNNDKEELVKEMVDVLYHCFVLLVEKNISLEDIMEEVTERNGKLSRVGDRREIDTL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_NITOC
Sequence: MAKPFKIIGLIGKQKDPRIAESLQQVADFLVAKGLTLMIDQETAALFPSHHWEAVTRHELGQRCDLAIVVGGDGTLLHVARSLADSGIPLLGIKLGRLGFLADVLPEALGTDLAAMLAGHYREEERFLLQAELEQESQSYLIGTALNDITTHIREVVRLIEFETYINGRFLNSQRSDGLVVATPTGSTAYALSAGGPILDVNLNAMVLVSICPHALSNRPLVIDADSLVEIVISEYNTTPGQVSCDGQPGIALKVGDKVKIYKRPGRVRLIHPTAHDHYSILRAKLHWGRKLG
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_SPHAL
Sequence: MKFFADTAEIDAIQELAATGLLDGVTTNPSLIAKSGRDFKEVTREICAIVDGPVSAEVVALDHETMMKEAEILRKIADNVCIKVPLTIDGLKTCKKLTGDGTMVNVTLCFSATQALLAAKAGATFVSPFVGRHDDNGFDGMQLIADIRLIYDNYDFGTEILVASVRHGIHVLEAAKIGADVMTAPPAVIKGLFKHVLTEKGIEGFLADWAKTGQSI
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_HELHP
Sequence: MQADLSNIIALYGGSFDPLHYAHMEIIRLLRENLLYKRIILMPNYRNPLKSSSFFTPLQRLQMCKILADEMNNAKSCNQKIPYISVSDYEVCQNRSVFSVQSVAFIKEQITKQDTNAQLVFVLGEDSFNNLKQWKDVEKLCKMVDFVLIKREISQKDSQISPHIVPYAHVIKCLDLPPSVAHFSSSSVRSLLQKGQIDEALNLVPVCLHTFIKANFRL
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ES2P_LITPI
Sequence: GFSSIFRGVAKFASKGLGKDLARLGVNLVACKISKQC
What is the function of this protein?
Antibacterial activity against Gram-negative bacterium E. coli.
What are the official names of this protein?
Esculentin-2P.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Esculentin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLYA_DICTD
Sequence: MRYLPEVDPEIYEAIKSEEYREEYHLELIASENFVSRAVLEAQGSVLTNKYAEGYPGKRYYGGCLYVDKVEDIARERVKAIYGAEHANVQPHSGSQANMAVYFVVLNPGDRVLGMNLAHGGHLTHGSPVNFSGKLYNFYFYGVDKNTEMINYDSVWNLAKELKPKLIVAGASAYPRIIDFEKFAQIAEDVGAYFMVDMAHIAGLVAAGLHPSPVPYAHFVTSTTHKTLRGPRGGFILCKKEFAKEIDKAVFPGIQGGPLMHVIAAKAVAFKEAMSPEFKEYQKQIVLNAKAMAEELIKLGYRLVSGGTDNHLMLVDLRDKGITGKEAEKALEEAGITVNKNAIPFDPQPPTITSGIRIGTPALTTRGMKEDEMRYIARLIHEVLSNFKDERVKEKVKKEVEELCKQFPIYRKEN
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_NITEC
Sequence: MTQMTVEQFAHDLGMLPNLLLEQLQAAGVAKRSAADFVTEQDKTQLLDYLRKSHGSSGSRTKITLARRQTTEIKQSDSAGRPRTIEVKVRKKRVLTTKQDESDAAGKRAAEDVSLRTAEAPEAPEAVPVKSVLDAEQIALRAEEARKRSELMARQAAELKEKQEKRRQQVTAQTEVKKESTQVQEPGSETAAVSGSVAATQPESTETAAVTPSATITVTTQTTPAAKERAPQKPAVKPEEKGEKKKKQARQQEAWKDEPVKRRESKARGDVSGGQEWRMRKDKHGRSRSDESQSQHAFSAPTEPVVHEVLIPETISVAVLAQKMAVKAAEVIKVLMKMGNMVTINQMLDQDTAMIVVEEMGHVAKIAAPDNPEAFLEEVDLSPDEARMESRAPVVTVMGHVDHGKTSLLDYIRRTRVAGGEAGGITQHIGAYHVKTSRGVVTFLDTPGHEAFTAMRARGAKITDIVILVVAADDGVMPQTIEAVHHAKAASIPIVVAVNKMDKPEANLERIKQELVNHGVVPEDWGGDAMFIGVSAKTGQGIDELLEAVLLQAEVLELKAVRDAPAKGVIIESRLDKGRGPVATVLVQSGTLRRGDVVLTGAVFGKIRAMLDERGKSVSEAGTSIPVEIQGLSEVAAAGEVFIALSDERKAREIALFRQGKFRDVRLDKLHVAKMEDVFGHQEDISTLNLIIKADVQGSCEALAYALKKLETDEVKINIVHSGVGAIIESDINLALASKAVVIGFNCRADLGARKLIASTGVDVRYYNIIYEAVDEVKKALSGMMTPDRKEKILGLVDIREIYRISKVGVVAGCYVLEGLIRRDAPVRVLRDGVVIHSGSLDSLKRFKDDVKEVKSGFECGLSLKNFNDIQQGDQIEVYEIVETARVL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_EXISA
Sequence: MTIKAEEISALLKERIASYGSEIEVSETGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEEGNVGIIILGDYKGIKEGDSVKRTGRIMEVPVGEALLGRVVNPLGQPIDGLGPIVTDTYNPIERKAYGVMARKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTSVAIDTIINQKEENMICIYVAIGQKESTVRGVVETLRQNGALDYTIVVSASASQPAPLLYLAPFAGVSMGEYFMDRGQHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDELGGGSLTALPFIETQASDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGSAQVKAMKKVAGTLRLDLASYRELEAFAQFGSDLDKATQSKLNRGQRTVEVLKQDLNAPLSVDKQVIIIYALTKGHLDDIPVTDIRRFETEMNAWLDQNRKDLCREIRQTGNLPSDEAMVDAITEFKKTFSPSV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VATH2_CAEEL
Sequence: MAEVPHHNIPAVDMLNATSRLQLEAQELRNNKPNWGSYFRSQMIQEDDYNFITSFENAKSKEERDQVLAANNANGQAAKTMANLITQVAKDQNVRYVLTLFDDMLQEDKSRVELFHSAAARQKRTVWSQYLGILQRQDNFIVNQMSSIIAKLACFGTTRMEGQDLQYYFSFLKEQLKNSTTNDYMNTTARCLQMMLRHDEYRHEFVDSDGVQTLVTALNGKTNFQLQYQLIFAVWCLTFNADIARKAPSLGLIQALGDILSESTKEKVIRIILASFVNILSKVDEREVKREAALQMVQCKTLKTLELMDAKKYDDPDLEDDVKFLTEELTLSVHDLSSYDEYYSEVRSGRLQWSPVHKSEKFWRENASKFNDKQFEVVKILIKLLESSHDPLILCVASHDIGEYVRHYPRGKTVVEQYQGKAAVMRLLTAEDPNVRYHALLAVQKLMVHNWEYLGKQLDSDVQTDTVAVK
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit H is essential for V-ATPase activity, but not for the assembly of the complex (By similarity).
What are the official names of this protein?
Probable V-type proton ATPase subunit H 2, V-ATPase subunit H 2, Vacuolar proton pump subunit H 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase H subunit family.
Protein: RIMP_ACIBT
Sequence: MKLSNKSQALYDMIAPAVEACGVDLWGIEFLPQGKRSLLRIYIDRPVDENAEPVINEDGEVEQGRGIGVEDCVRVTQQVGAMLDVHDPISGEYALEVSSPGWDRPFFQLEQLQGYIGQQVALRLIAAVENRRKFQAKLLAVDLENEEIQVEVEGKHVLDIDSNNIDKANLIYQD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: L3BPB_DANRE
Sequence: MLLLWPLLFLQVSALRRTLFDRPKQLMQEGRVRLVGVIPSSGRVEVYHDGQWGTVCDDGWDLAEAQVVCRQLGFPGAVSVATGGQYGEGSGRVWLDDMNCKGSESLLSECSFKGWGVSDCTHKEDAGVICAPGKNTTSIRQMSVDNSLGLSDDLGLLFDSEDGCDFTIAVRDLSEEAELTFCVHRVILMIYPELNLTHDTRNITVDISQTCHTHVPRFLRYLYTRQIDVSTTSAQCLHQLAFIFGVQKLMEDVGRVFTALIPEDNTFQTQVSMYEYGVRTGDLVLQENVLQYLSWNCEFLISSPVWSTVSFDMMDALLQRSDLIVKDEAVLLEALERWIQDKGDQISSDKQVSLLNHIRFLLIPVDKLYDIQFSSSALRQSNEKLYLTGLLRGFQFNALPFSKIRDQVVKLSGNYIPRIYIGDEWSLGLNVSTVNNPHYNPYQYGYDQRYGQSNRIEKYLSTPAHPSAVYRGQMIQWQAQVFRSVQDCRNSGISCNSVPLVRFLATSSQYSYSSTIRYNNRLVLTCKNQNNVFHVQDFKNNMAVIPTNSSMGLPNPCPDDYSFRFVVRPQYI
What is the function of this protein?
Promotes integrin-mediated cell adhesion.
What are the official names of this protein?
Galectin-3-binding protein B, Lectin galactoside-binding soluble 3-binding protein B.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix.
Protein: SYDND_SYNY3
Sequence: MRTHYCGDLRTTHLGETVTLYGWVDRRRDHGGVIFLDLRDRQGIVQIASSPDQTPASYPVAEGLRNEYVVQVTGVVSKRPPESLNEKIPTGEIEIYADSIILLNGVNQQLPFVVSSHEAEQVREDVRLKYRYLDLRRARLSQNLQLRHQVVKAMRRFLEDQENFLEIETPILTRSTPEGARDYLVPSRVNPGEWYALPQSPQLFKQLLMVAGMDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFMGQEEILDLNEALICHIFKVVKNIDLPRPFPRLTYQESMAKYGNDRPDTRFGLELVDVSDLLGNTGFKVFSAAVSSGGSIKAIRVPGGNETISNVRIKPGGDLFKEATEAGAKGIAYIRVRDNGEIDTIGAIKENLDEAQVKTLLQLTQAEAGDLLLFGAGDTATVDKSLSRLRLVLGEQLGLIDPDAINLLWITDFPMFEWNSDEKRFEALHHPFTAPHPDDLGDLKTARAQAYDLVMNGVEIGGGSLRIYQREVQEKVFATIGLSPEEAHEKFGFLLDAFEYGTPPHGGIAYGLDRLVMLLAKEDSIRDVIAFPKTQQASCLLTEAPAAVDKKQLKELSVASTYVPKVKVDD
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_CROS8
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPQKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKSPSIKIETLVPDFRGRMDRALEILTATPPDVFNHNLENVPRLYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNAEIIEVMRDLRAHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFEEMKAEAMAMGFTHAACGPFVRSSYHADLQAKGEEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TACY_CLOTE
Sequence: MNKNVLKFVSRSLLIFSMTGLISNYNSSNVLAKGNVEEHSLINNGQVVTSNTKCNLAKDNSSDIDKNIYGLSYDPRKILSYNGEQVENFVPAEGFENPDKFIVVKREKKSISDSTADISIIDSINDRTYPGAIQLANRNLMENKPDIISCERKPITISVDLPGMAEDGKKVVNSPTYSSVNSAINSILDTWNSKYSSKYTIPTRMSYSDTMVYSQSQLSAAVGCNFKALNKALNIDFDSIFKGEKKVMLLAYKQIFYTVSVDPPNRPSDLFGDSVTFDELALKGINNNNPPAYVSNVAYGRTIYVKLETTSKSSHVKAAFKALINNQDISSNAEYKDILNQSSFTATVLGGGAQEHNKIITKDFDEIRNIIKNNSVYSPQNPGYPISYTTTFLKDNSIASVNNKTEYIETTATEYTNGKIVLDHSGAYVAQFQVTWDEVSYDEKGNEIVEHKAWEGNNRDRTAHFNTEIYLKGNARNISVKIRECTGLAWEWWRTIVDVKNIPLAKERTFYIWGTTLYPKTSIETKM
What is the function of this protein?
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol-containing host membranes (PubMed:6997696).  After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex.  Cholesterol is required for binding to host membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus (By similarity).
What are the official names of this protein?
Tetanolysin, Tetanolysin O, Thiol-activated cytolysin.
What is the protein family that this protein belongs to?
Belongs to the cholesterol-dependent cytolysin family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein. Note=Secreted as soluble protein that then inserts into the host cell membrane and forms huge pores formed by transmembrane beta-strands.