PharMolix/UniProtQA huggingface dataset:
Protein: DCTA2_RHILO
Sequence: MHIADQSGAAAAQRKPLYAQLYVQVLVAITVGILLGHYYPSIGESMKPLGDAFIKLVKMIIAPVIFLTVATGIAGMSDLQKVGRVAGKAMLYFLTFSTLALIIGLVVANVVQPGAGFNIDPATLDASTVNTYAAKAHDQSVTGFLMNIIPGTIVGAFADGDILQVLFFSVLFGIALALVGDKGAPVLNFLQALMAPMFKLVSVLMKAAPIGAFGAMAFTIGKYGIGSVINLAMLVGTFYATSLLFVFVVLGAVCRYNGFSILSLLRYIKEELLLVLGTSSSEAALPSLMEKMEKAGAKRSVVGLVIPTGYSFNLDGTNIYMTLAALFIAQATNIHLSMGDQILLLLVAMLSSKGAAGITGAGFITLAATLSVVPSVPVAGMALILGVDRFMSECRALTNFIGNAVATLVVARWEGELDEAKLARALAGTADDSLPADIVPAE
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.  This transport system plays an important role in the energy supply of rhizobium-legume symbionts (By similarity).
What are the official names of this protein?
C4-dicarboxylate transport protein 2.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELN_MOUSE
Sequence: MGQARPAARRPHSPDPGAQPAPPRRRARALALLGALLAAAAAVAAARACALLADAQAAARQESALKVLGTDGLFLFSSLDTDQDMYISPEEFKPIAEKLTGSVPVANYEEEELPHDPSEETLTIEARFQPLLMETMTKSKDGFLGVSRLALSGLRNWTTAASPSAAFAARHFRPFLPPPGQELGQPWWIIPGELSVFTGYLSNNRFYPPPPKGKEVIIHRLLSMFHPRPFVKTRFAPQGTVACLTAISDSYYTVMFRIHAEFQLSEPPDFPFWFSPGQFTGHIILSKDATHIRDFRLFVPNHRSLNVDMEWLYGASETSNMEVDIGYVPQMELEAVGPSVPSVILDEDGNMIDSRLPSGEPLQFVFEEIKWHQELSWEEAARRLEVAMYPFKKVNYLPFTEAFDRARAEKKLVHSILLWGALDDQSCUGSGRTLRETVLESPPILTLLNESFISTWSLVKELEDLQTQQENPLHRQLAGLHLEKYSFPVEMMICLPNGTVVHHINANYFLDITSMKPEDMENNNVFSFSSSFEDPSTATYMQFLREGLRRGLPLLQP
What is the function of this protein?
Plays an important role in cell protection against oxidative stress and in the regulation of redox-related calcium homeostasis.  Regulates the calcium level of the ER by protecting the calcium pump ATP2A2 against the oxidoreductase ERO1A-mediated oxidative damage.  Within the ER, ERO1A activity increases the concentration of H(2)O(2), which attacks the luminal thiols in ATP2A2 and thus leads to cysteinyl sulfenic acid formation (-SOH) and SEPN1 reduces the SOH back to free thiol (-SH), thus restoring ATP2A2 activity (PubMed:25452428).  Acts as a modulator of ryanodine receptor (RyR) activity: protects RyR from oxidation due to increased oxidative stress, or directly controls the RyR redox state, regulating the RyR-mediated calcium mobilization required for normal muscle development and differentiation (By similarity).  Essential for muscle regeneration and satellite cell maintenance in skeletal muscle (PubMed:21131290).
What are the official names of this protein?
Selenoprotein N, SelN.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane.
Protein: SYI_STAA1
Sequence: MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFDVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAGTGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQTSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_LISIN
Sequence: MPNIKSAIKRVKTAETRNSRNASQRSAMRTAIKKFDEAAANNADNAKDLYVEASKKLDSAVSKGLIHKNNAARNKSRLAAKLAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: UNG_HELP2
Sequence: MKLFDHAPLSLAWREFLQSEFKKPYFLEIEKRYLEALKSPKTIFPKSSNLFHALNLTPPSAVKIILLGQDPYHSTYLKKEQELPVAMGLSFSVEKNAPIPPSLKNIFKELHANLGVPVSCCGDLSAWAKRGMLLLNAILSVEKNQAASHKYIGWEAFSDQILMRLFKTTAPLIVVLLGKVAQKKIVLIPKNKHIIITAPHPSPLSRGFLGSGVFTSVQKAYREVYRKDFDFSL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_ECOHS
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVEPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEGLLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_BORPE
Sequence: MRHGNGLRKLNRTSSHRLAMFRNMAVSLITHEAIKTTLPKAKELRRVIEPLITLGKEPTLANKRLAFARLRDRDAVVKLFAEIGPRYANRNGGYTRVLKMGFRQGDNAPMAFMELVDRPEVDASEADSDAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RSMH_DESAL
Sequence: MAFHHVSVMKQEVLSLLSPAPGHVVVDGTFGGGGHARAILERILPDGLLIGTDLDEDAVTNAQACFADVQNNFRIFHDNFSNIRAVLDQCGLAGANGIVLDLGVSLHLLEKSGRGFSFQREEPLDMRMDGSGGGPKAMDVVNAYSQDELARIFLEYGEERQAKRIARRIVQRREDEPITTSGRLADIVASAVKGKPGRIHPATRVFQALRIHVNNELAHLEKFLETCLDCLLPGGRLCIISFHSLEDRIVKRRFAALAQGCTCPPDFPVCICGNQPKVKILTKKVVKPSQAEVEKNPMSRSAKIRAMEKLAVEGSGAGGEDGRAKQ
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_CAUVN
Sequence: MSEEQKLPKEPPILLPGAADFTEEQIEAARVFFAQPVSFIMGAVRMDAMPPSDLPEVAFAGRSNVGKSSLINGLVNQKYLARASNEPGRTREINFFLLAEKVRLVDLPGYGFARVSRSIADKFQDLGRAYLRGRANLKRVYVLIDARHGLKKVDLEALDALDVAAVSYQIVLTKADKIKPAEVDKVVAETQKAIAKRAAAFPRVLATSSEKGLGMPELRAEIVRLCIDE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RS19_PYRCJ
Sequence: MSSKEAEAQKGKQGWITPTVIPPEEWGSFRYRGKTLEELLNMPMDEFIKLLPARQRRSLKRGLKPEHRKLLEKIRKAKRLMAQGKKVTIKTHCRDMIILPEMVGLTIHVYNGITYIPVFISPWHIGHYLGEFALTTRIVQHGEPGLKATRSSLHIAAK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: HLDE_ECOSE
Sequence: MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVNTIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASVQQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMKLIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAAARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANGGEVLVLNFEDGCSTTNIIKKIQQDKKG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RIBBA_BACSU
Sequence: MFHPIEEALDALKKGEVIIVVDDEDRENEGDFVALAEHATPEVINFMATHGRGLICTPLSEEIADRLDLHPMVEHNTDSHHTAFTVSIDHRETKTGISAQERSFTVQALLDSKSVPSDFQRPGHIFPLIAKKGGVLKRAGHTEAAVDLAEACGSPGAGVICEIMNEDGTMARVPELIEIAKKHQLKMITIKDLIQYRYNLTTLVEREVDITLPTDFGTFKVYGYTNEVDGKEHVAFVMGDVPFGEEPVLVRVHSECLTGDVFGSHRCDCGPQLHAALNQIAAEGRGVLLYLRQEGRGIGLINKLKAYKLQEQGYDTVEANEALGFLPDLRNYGIGAQILRDLGVRNMKLLTNNPRKIAGLEGYGLSISERVPLQMEAKEHNKKYLQTKMNKLGHLLHF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: DP2L_THEVO
Sequence: MTILHSTMLSEVLDLESYRKKISDEVRECFDLASQARELGMDVTDKVEIPLASDMAERIEALIGISGIADQIRDLSKKMSREEVSLEMSRRVANIFKDNKKEALDKAIRVGLAILTEGILVAPLEGIADVYIGKNADGSDYVGISYAGPIRGAGGTAQALSVLIGDVVRRELGITRYIPTEEEIERYIEEIESYDRIKHLQYLPTPDEIKLVVKNSPVCIDGEGSEEEEVSGHRDMARVKTNRIRGGMCLVLCEGLVQKARKILKYTSSMHLEEWSFLSSISGKSDDKGSKKSDKFLKDIVAGRPVFSHPSRPGGFRLRYGRSRVSGLAAASLNPATMYIMGKFIAIGSQIKVELPGKAAAVTPCDTIDGPTVLLRNGDHVKINNIEKAKELYDEVVEITDAGEILIAYGDFLENNYNLPTASFTKEWWMQYLPDGLDGNEVDQFRAVELSRQYNIPLHPDFDYYWHDISFEELEYLISAVENGRLSDNSFLIPYSASEVLIKLGVQFKRSGNFLVLNQYYPLLVSLGYDVFEDKIKRVKPYQRKSSVLETVNYLSGITIKPRAPTRVGSRLGRPEKAGDRKMKPMVHSLFPVESYGEARRSILNANKKTDGTYKAEVFFYRCTSCGYESPSPTCPKCGSRSKPIGTKNSEIDLSVILRKAEDRLGIKLDELKEFKGVKKLMSKEKVAEPIEKGILRAIHGISVNKDGTCRFDMSDIPITHFRYKEIGISKEKLSELGYEVKDVNEIFPQDVIIPRKAAKYLFDVSKFIDDLLVRYYGLPPFYSLKSEEDLVGHLVIGLAPHTSGGVVGRIIGFSDVNAFYAHPFFHAAKRRNCDGDEDSVMLLMDGFLNFSARYLPSTTGGLMDAPLVLSVLINPDEIDKEALNVDTLQKYPLIFYEATERHAAPSELEETMMTMKVRIKKTATYRNSSYTFDTSDINKGVLVSSYKTLATMDDKISEQLGLARRIRAVDADDVAARVISTHFLPDMYGNFRRFFSQEFRCTKCNAKYRRIPLSGRCMKCGSDSLTLTIHKGSVIKYLDETLKIEKEYNIPKYLKERIDNLARTIKETFPDEEKPDAAIKITGLDMY
What is the function of this protein?
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.  Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase II large subunit, Pol II, Exodeoxyribonuclease large subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeal DNA polymerase II family.
Protein: NUSB_TREPS
Sequence: MSEVFPKIGRRRARILAFQALFAWDAAGITPETLTQFTWLRRNPPPSTQDLGFSRLLFLGTLEHLREIDGCVSSRLEHWDFVRLNKVDKAILRLSAYSLLFQKDIPPVVVIHEAVSIARDFGTDDSFRFVNGVLDNIAKSA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: AP3M1_MOUSE
Sequence: MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAYFDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQNMGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLAWDVGKITPQKLPSLKGLVNLQSGAPKPEENPNLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated.  The complex is associated with the Golgi region as well as more peripheral structures.  It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
What are the official names of this protein?
AP-3 complex subunit mu-1, AP-3 adaptor complex mu3A subunit, Adaptor-related protein complex 3 subunit mu-1, Mu-adaptin 3A, Mu3A-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: IDA_ARATH
Sequence: MAPCRTMMVLLCFVLFLAASSSCVAAARIGATMEMKKNIKRLTFKNSHIFGYLPKGVPIPPSAPSKRHNSFVNSLPH
What is the function of this protein?
Involved in an ethylene-independent separation step of floral abscission (PubMed:18660431, PubMed:23963677, PubMed:27058169).  Promotes abscission zone (AZ) cells rounding (PubMed:23963677, PubMed:27058169).  May act with RLK5 and HSL2 as ligand-receptor pairs (PubMed:18660431).
What are the official names of this protein?
Protein IDA, Protein INFLORESCENCE DEFICIENT IN ABSCISSION.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: GPDA_FUSNN
Sequence: MVKISVIGSGGWGIALAILLHKNGHNLTIWSFDKKEAEELKINRQNKTKLPNILLPEDIKVTDNLKEAVDNKDILVLAVPSKAIRSVSKSLKDIIKDNQIIVNVAKGLEEDTLKTMTDIIEEELKEKNPQVAVLSGPSHAEEVGKGIPTTCVVSAHNKELTLYLQNIFMNPSFRVYTSPDMIGVEIGGALKNVIALAAGIADGLNYGDNTKAALITRGIKEISSLGVAMGGEQSTFYGLTGLGDLIVTCASMHSRNRRAGILLGQGKTLDEAIKEVNMVVEGIYSAKSALMAAKKYNVEIPIIEQVNAVLFENKNAAEAVNELMIRDKKLEIQSW
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYAS2_BOVIN
Sequence: MHCERFLCILRIIGTTLFGVSLLLGITAAYIVGYQFIQTDNYYFSFGLYGAFLASHLIIQSLFAFLEHRKMKKSLETPIKLNKTVALCIAAYQEDPDYLRKCLQSVKRLTYPGIKVVMVIDGNSEDDLYMMDIFSEVMGRDKSATYIWKNNYHVKGPGETDESHKESSQHVTQLVLSNKSICTMQKWGGKREVMYTAFRALGRSVDYVQVCDSDTMLDPASSVEMVKVLEEDPMVGGVGGDVQILNKYDSWISFLSSVRYWMAFNIERACQSYFGCVQCISGPLGMYRNSLLHEFVEDWYNQEFMGSQCSFGDDRHLTNRVLSLGYATKYTARSKCLTETPIEYLRWLNQQTRWSKSYFREWLYNAMWFHKHHLWMTYEAVITGFFPFFLIATVIQLFYRGKIWNTLLFLLTVQLVGLIKSSFASCLRGNIVMVFMSLYSVLYMSSLLPAKMFAIATINKAGWGTSGRKTIVVNFIGLIPVSVWFTILLGGVIFTIYKESKKPFSESKQTVLIVGTLLYACYWVMLLTLYVVLINKCGRRKKGQQYDMVLDV
What is the function of this protein?
Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer.  Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation (By similarity).  This is one of three isoenzymes responsible for cellular hyaluronan synthesis and it is particularly responsible for the synthesis of high molecular mass hyaluronan (By similarity).
What are the official names of this protein?
Hyaluronan synthase 2, Hyaluronate synthase 2, Hyaluronic acid synthase 2, HA synthase 2.
What is the protein family that this protein belongs to?
Belongs to the NodC/HAS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Vesicle. Golgi apparatus membrane; Multi-pass membrane protein. Lysosome. Note=Travels from endoplasmic reticulum (ER), Golgi to plasma membrane and either back to endosomes and lysosomes, or out into extracellular vesicles. Post-translational modifications control HAS2 trafficking.
Protein: QUEF_SHISS
Sequence: MSSYANHQALAGLTLGKSTDYRDTYDASLLQGVPRSLNRDPLGLKADNLPFHGTDIWTLYELSWLNAKGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQTRFNNWDEVRQTLERDLSTCAQGKISVALYRLDELEGQPIGHFNGTCIDDQDITIDNYEFTTDYLENATCGEKVVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRQIDREKLLRYLVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPWRSNSDFVPSTTRLVRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_GRAFK
Sequence: MNTDPIADYLTRIRNANAANHRVVEIPASNVKKEITKILFDQGYILSYKFEDTTAQGTIKIALKYDKLTKEPVIKKIQRISKPGLRKYAGSTEIPRILNGLGIAVVSTSHGVMTGKQAKANKVGGEVLCYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CH10_LISMO
Sequence: MLKPLGDRVVIEVLEAEEKTASGIVLPDSAKEKPQSGKIVAVGSGRVLDNGTKEPLEVAEGDTVIFAKYSGTEVTYEGTDYLILRESDILAITK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC22_MAGML
Sequence: ADAPAGFTLCKACHSVEAGKNGVGPSLAGVYGRKAGTISGFKFSDPHIKSGLTWDEPTLTKYLADPKTVIPGNKMVFAGLKNPDDVKAVIEYLKTLK
What is the function of this protein?
Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway.  However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
What are the official names of this protein?
Cytochrome c2 iso-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
Protein: ODPAT_RAT
Sequence: MRKMLATVLSQVFSGMVQKPALRGLLSSLKFSNDATCDIKKCDLYLLEQGPPTSTVLTREEALKYYRNMQVIRRMELKADQLYKQKFIRGFCHLCDGQEACNVGLEAGINPTDHIITSYRAHGLCYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGVALACKYLKNGQICLALYGDGAANQGQVFEAYNMSALWKLPCVFICENNRYGMGTAIERSAASTDYHKKGFVIPGLRVNGMDILSVREATKFAADHCRSGKGPIVMELQTYRYHGHSMSDPGISYRTREEVQNVRSKSDPIMLLRERMISNNLSSVEELKEIDADVKKEVEEAAQFATTDPEPPLEDLANYLYHQNPPFEVRGAHKWLKFKSVS
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial, PDHE1-A type II.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: KHSE_SYMTH
Sequence: MVRVSVPATSANLGPGFDTLGVALELRNVIEMDETGIDDVVIEVEGAGAGALEDPGRNMVYQAARLVFQRLGYEPNGLLIREKVAIPVARGMGSSAAAIVGGLVAANALVQKRTGGPGLDREELLRMAVAIEGHPDNVTPALLGGFTVSCMDPDRGPLYLCFPPPRGLRAVVVMPEVQIKGRKTEQSRGVLPAQVSLRDAVYNLNRTALLVAAVAQGRTDLLRVAMQDRLHQPYRAALVPGMRSVFEAALSAGALGVALSGAGPSVIALVAESAEPVALAMEAAFQWAGSNARSLTMDLAREGARVLSGPGREQDMLDRPPHWG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_ANAMM
Sequence: MRRSVFCGVGAFLPAKVITNDDLSLMVDTTDEWVFRRTGIKRRHVVEEGDTVSCMATEAAKIALEDAGVSATEVDLIIVATATPDKTMPSCATMVQGSLGCKNAAAFDINAACSGFLYALSIVDSMIKAGQANIALIIGSEAMSKVVDWTDRSTCVLFGDGAGAFVFKGQDETEKPGAGVMSTLLCADGSLGNVLYTNGGVASTGKAGYICMKGTVLFEHAVVKLSSAISALLESSALDVDSIDWFIPHQANVRIIDLVINRLGLSRDKVILSIDEHANTSSASIPLAMYEAKRAGRIKKGNLVLFAAIGAGITWGVSLLRL
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOVO_LOPSP
Sequence: VATVDCSGYPKPACTMEYMPLCGSDNKTYGNKCNFCNAVVDSNGTLTLSHFGEC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: THIG_SHEPW
Sequence: MLKIGDTEFTSRLFTGTGKFANDKNMLAAIGASNSELVTLAVKRLDLKTGSDNILKPLQQRRVKLLPNTAGARNVKEAIFAAHLSREMLGTNWIKLEIHPDPKYLMPDPIETLAAARILCEQGYVVLPYVHADPVLCRRLEEVGCAAVMPLGSPIGSNQGLATEPFLKIIIEQSQVPVVIDAGIGAPSQATRAMELGADAVLVNTAIASSADPVAMGRCFAQAVDTGRAAFIAGLGNVSEQANSTSPLTGFLNV
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.