PharMolix/UniProtQA huggingface dataset:
Protein: TGTP2_MOUSE
Sequence: MAWASSFDAFFKNFKRESKIISEYDITLIMTYIEENKLQKAVSVIEKVLRDIESAPLHIAVTGETGAGKSTFINTLRGVGHEEKGAAPTGAIETTMKRTPYPHPKLPNVTIWDLPGIGTTNFTPQNYLTEMKFGEYDFFIIISATRFKENDAQLAKAIAQMGMNFYFVRTKIDSDLDNEQKFKPKSFNKEEVLKNIKDYCSNHLQESLDSEPPVFLVSNVDISKYDFPKLETKLLQDLPAHKRHVFSLSLQSLTEATINYKRDSLKQKVFLEAMKAGALATIPLGGMISDILENLDETFNLYRSYFGLDDASLENIAQDLNMSVDDFKVHLRFPHLFAEHNDESLEDKLFKYIKHISSVTGGPVAAVTYYRMAYYLQNLFLDTAANDAIALLNSKALFEKKVGPYISEPPEYWEA
What is the function of this protein?
Involved in innate cell-autonomous resistance to intracellular pathogens, such as Toxoplasma gondii (PubMed:19265156, PubMed:20109161, PubMed:24563254).  During avirulent type II T.  gondii infection, recruited to the parasitophorous vacuole (PV) membrane, leading to PV vesiculation and rupture, and subsequent digestion of the parasite within the cytosol (PubMed:19265156, PubMed:24563254).  Not recruited to virulent type I T.  gondii PV membrane (PubMed:19265156).  May confer an antiviral state for vesicular stomatitis virus (PubMed:9725230).
What are the official names of this protein?
T-cell-specific guanine nucleotide triphosphate-binding protein 2, Interferon-gamma-inducible GTPase Ifggb6 protein, T-cell-specific guanine nucleotide triphosphate-binding protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Golgi apparatus. Note=In astrocytes stimulated with IFNG or TNF, diffuse cytoplasmic localization decreases and the protein partially relocalizes to the endoplasmic reticulum and Golgi apparatus (PubMed:19285957). Due to sequence similarity with Tgtp1, it is impossible to assign unambiguously experimental data published in the literature to Tgtp1 or Tgtp2 gene (Probable).
Protein: RL18_STAA8
Sequence: MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RF1_AGRFC
Sequence: MAKLPVEKMRELERRFGEIEARMSAGPAADVYVKLASEYSELEPVVKKIRDYEKAISEAADLEALLADKTTDKDMRDLAEMELPEVETRIRELEKDMQVLLLPKDAADEKSAILEIRAGTGGSEAALFAGDLFRMYERFAATKGWKVEVLSASEGEAGGYKEIIATITGRGVFSKLKFESGVHRVQRVPETEASGRIHTSAATVAVLPEAEDIDVEIRPEDIRIDTMRASGAGGQHVNTTDSAVRITHLPTGLIVTSSEKSQHQNRAKAMQVLRSRLYDIERQKVDSERSADRKSQVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDRVIEGEIDELVDALIADYQAGQLAQLGEQQL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSIA_SALTI
Sequence: MPHSDELDSRDVLSVSGLNIAFHHEGQQVDAVRNVSLRLKRGETLTIVGESGSGKSVTALALMRLIEQSGANVRCGEMLLRRRNRQVIELSEQSDAQMRRVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEALAEAKRMLDQVRIPESQAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQEMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPTHPYTQTLLAAVPQLGAMRGHSLPRRFPLISADEPALYESQIEQDTVVEGEPILQVRGLVTRFPLRSGLFNRVTREVHAVENISFDLWPGETLSLVGESGSGKSTTGRALLRLVESRQGEIIFNGQRIDTLSAGKLQPLRRDIQCIFQDPYASLDPRQTVGYSIMEPLRIHGLGQGDAAAKRVAWLLERVGLRPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSVRGQIINLLLDLQREMGIAYLFISHDMAVVERISHRVAVMYLGQIVEMGPRRAVFENPQHPYTRKLMAAVPVADPSRHRPRRVLLSDDIPSNIHKRGEETPAVSLQLVGPGHYVARPLQDNALSRL
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Glutathione import ATP-binding protein GsiA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Glutathione importer (TC 3.A.1.5.11) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DUT_ENCCU
Sequence: MTVSEIRVRKINPRAKIPKRQSEGAAGYDIHSVESGRIPPNGRKSVRTGLAWDVPQSVVGLVFGRSGLALRNWIEVVETCVHPGEDKELVITLVNNGREVFEYEESSRIAQLVFVPVLSCEIDLVESLDLTERGCLGFGSTGMK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: NADE_BACCR
Sequence: MTLQEQIMKALHVQPVIDPKVEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVEEIRNEGGNVTFIAVRLPYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYENLLGESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDHAAEAVTGFFTKFGDGGADLLPLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKAVPADVAEKIEKRYTVSEHKRQVPASMFDDWWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: MRAY_CHLTR
Sequence: MLPLTYVVKAFSIGLFFSLFLMKPLISWLKKQGFQDHIHKDHCEKLEELHKDKAYIPTAGGIVFVFASVLAVLLLFPIQLWSTWFCIGTILLWGALGWCDDQIKNRRRVGHGLSAKHKFLIQNCLAAGVVLPIMFAYKESFLSFHLPFLGIVSLPHHWWSYLLSFAIATLAIVGTSNSVNLTDGLDGLAAGAMVIACLGMLVVACTNGAPWAFICCVLLATLAGSCLGFLRYNKSPARVFMGDTGSLFLGAMLGMCAVLLRAEFLLLFMGGIFVLESLSVIVQVGSYKLRKKRVFLCAPLHHHYEYKGLSEKAVVRNFLIVELICVVVGIIAVFVD
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GRAS_STAHJ
Sequence: MSNLKWFWLFLKTRSNWIFWIVFLHLILLGMAYIDYDISIESIGFIVTLNLGLTAMFLIFTFLKEVKLYQHLYNNKEIEEIKHKDLAEDPFQKEVVNYLYRKLTSQKERVVEQQLHIQSTEQSLTEFVHDIKTPVTAMKLLIDQEEEGKRKKSLLYEWARINELLDKQLYLTRLESKNRDMYFEETSLKRLVIDEVQLTRHISQAKGIGYDLDLETNLDVYTDVKWCRMMIRQILSNSLKYSQGQDIIIRSYTNDGHVTLEIKDFGRGISHKDLPRIFERGFTSTVNRNETTSSGIGLYLVNSVKDQLGINVRVESTVGQGTTFVLTFPKQNELMARMTQVTTM
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).  GraS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to GraR (By similarity).
What are the official names of this protein?
Sensor histidine kinase GraS, Glycopeptide resistance-associated protein S.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPIA_LEVBA
Sequence: MDQNALKALVGQEAVKYVEDGMILGIGTGSTVRYMIDALGERVKNEGLHIIGVATSDRSAKQAESLGITIKELDEVDHLDLTIDGADEIDDNFQGIKGGGAAHLWEKIVAINSTKNMWIVDESKMVHHLGAFPLPLEVIPFGSSHVLEKLNKMGFNPSFRMTDTGEHVLTDSKNYIIDLHLGRIDHPHDLANTLNGIVGVVEHGLFLDTVNTVIVGRQDGPEVLNARD
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: KFA_DANRE
Sequence: MSDWKSMSKDELELQYSPSRWSPRMSADDVIRAHVSALKSGTERARSVTQTLMDVPYGEAEGEKLDVYLPSSSSPDVPLVIYFHGGYWQFLSKDESGFLAVPLVQKGAVVVAVGYSIAPKGDMDLMVSQVRRSVVSVIQQYSHISGLYLCGHSAGAHLAAMVLSTDWTQYDVSPKIKGAFLVSGIYDLQPILSTYVNEPLKMTEEVALRNSPSRFLSQLKVSSASCDITVAVAQNDSPEFRKQSEEYYKALESAGLKVSFEDVSETDHFSIIEQLVDENYLLTKLLLKMIGKS
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.  Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H).  Required for elimination of toxic metabolites.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the kynurenine formamidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: RIMK_PSEPK
Sequence: MKIAVLSRNPRLYSTRRLVEAGTQRGHEMVVIDTLRAYMNIASHKPQIHYRGKPLEGFDAVIPRIGASVTFYGCAVLRQFEMMGVYPLNESVAIARSRDKLRSLQLLSRRGIGLPITGFAHSPDDIPDLIQMVNGAPLVIKVLEGTQGIGVVLCETPQAAESVIEAFMGLKQNIMVQEYIKEAGGADIRCFVVGDKVIASMKRQAKPGEFRSNLHRGGVASLIKITPEERITAIRAAKVMGLSVAGVDILRSNHGPLVMEVNSSPGLEGIEVTTGKNVAGMIIEHLEKNGGPNQTRTKGKG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: LDH2_LISMO
Sequence: MKPRKVMIIGAGNVGTAAAHAFVNQKFVEELILVDLNKERVEGNRKDLADAAAFMPGKMDITVRDASDCADVDIAVITVTAGPLKEGQTRLDELRSTSRIVSGIVPEMMKGGFNGIFLIATNPCDIITYQVWKLSGLPRERVLGTGVWLDTTRLRRLLAEKLDIAAQSIDAFILGEHGDSQFPVWSHSSIYGKPVNEYSLEKLGESLDLKQIGETARDTGFEIYHQKGCTEYGIGGTIVEICRHIFSGSQRALTVSCVLDGEYGESGLAIGVPAVLSQNGVKEIISLKLDEQEQQAFANSVSVIKKSIASI
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 2, L-LDH 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1224_RICAE
Sequence: MVNFNQFLKQAQSMQKKMQEAQEQMANARYTGKAGGGLVEVIATGKGEVEKISIDESLLKAEEKEMLEDLIKVAFNDAQQKCDEDSQNSLSGALNGMRLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein RAF_ORF1224.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SRD44_CAEEL
Sequence: MFRKILSVLNPTVFVLSLCFQIILIYTIIRHSPKNLSTLKAILLTNCCFQLLQSSMVFFTQIQLVNHLVPIELWSYGPCRHFEAFMCYSMFHILQTSSLVSGLTVFLTTFMKYQAARHVRPSKKKNCFVILFISSIVLISAGCGILLVIIQALPLEIREKYYRINLELDEYSVIGIVDYSVLPSRVNGIIINGLVVIVPITCLLLRRKILKLLTASSDALYFQNRVFLQGLTLQIFGHTLVYVPIFICSTISLITKTEYTFAQFFIFVLPHLTTVIDPLLTMYFVTPYRKRLMVWLRLKNDKVHSVSPSTFAVSANH
What are the official names of this protein?
Serpentine receptor class delta-44, Protein srd-44.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srd family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SCTN_SHIFL
Sequence: MSYTKLLTQLSFPNRISGPILETSLSDVSIGEICNIQAGIESNEIVARAQVVGFHDEKTILSLIGNSRGLSRQTLIKPTAQFLHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDFGEYKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR
What is the function of this protein?
ATPase component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:26947936, PubMed:27770024, PubMed:29595954).  Acts as a molecular motor to provide the energy that is required for the export of proteins (Probable).  Required for type III secretion apparatus (T3SA) formation, proper protein secretion, host cell invasion and virulence (PubMed:26947936, PubMed:27770024, PubMed:31162724).  May play a critical role in T3SS substrate recognition, disassembly of the effector/chaperone complex and unfolding of the effector in an ATP-dependent manner prior to secretion (By similarity).
What are the official names of this protein?
Type 3 secretion system ATPase, T3SS ATPase.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITB2_OVICA
Sequence: MLPQRPQLLLLAGLLSLQSVLSQECTKYKVSTCRDCIESGPSCAWCQKLNFTGQGEPDSTRCDTRAQLLSKGCPADDIMEPKSLAETRQSQAGRQKQLSPEEVTLYLRPGQAAAFNVTFQRAKGYPIDLYYLMDLSYSMVDDLANVKKLGGDLLRALNDITESGRIGFGSFVDKTVLPFVNTHPEKLRNPCPNKEKECQPPFAFRHVLKLTDNSKQFETEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNLYKSSNEFDYPSVGQLAHKLAESNIQPIFAVTKKMVKTYEKLTEIIPKSAVGELSEDSKNVVELIKSAYNKLSSRVFLDHNTLPDTLKVAYDSFCSNRVSQVDQPRGDCDGVQINVPITFQVKVTATECIQEQSFTIRALGFTDTVTVRVLPQCECQCREASRDRGVCGGRGSMECGVCRCDAGYIGKNCECQTHGRSSQELEGSCRKDNSSIICSGLGDCICGQCVCHTSDVPNKKIYGQFCECDNVNCERYDGQVCGGDKRGLCFCGACRCNDQYEGSACQCLKSTQGCLNLNGVECSGRGRCRCNVCQCDPGYQPPLCIDCPGCPVPCAGFAPCTECLKFDKGPFAKNCSAACGQTKLLSSPVPGGRKCKERDSEGCWMTYTLVQRDGRNRYDVHVDDMLECVKGPNIAAIVGGTVGGVVLVGILLLAIWKALTHLSDLREYHRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES
What is the function of this protein?
Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4.  Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL.  Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen.  Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain.  Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain.  Integrin ITGAM/ITGB2 is also a receptor for factor X.  Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1.  Contributes to natural killer cell cytotoxicity.  Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils.  Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.  Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages.  In association with alpha subunit ITGAM/CD11b, required for CD177-PRTN3-mediated activation of TNF primed neutrophils.
What are the official names of this protein?
Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft; Single-pass type I membrane protein.
Protein: Y802_STRZT
Sequence: MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAVRHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS
What are the official names of this protein?
UPF0291 protein SPT_0802.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP14L_HUMAN
Sequence: MAGGGSDLSTRGLNGGVSQVANEMNHLPAHSQSLQRLFTEDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNLVPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDRKEREERPDIKLSLKQGEVPESPEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQNDNSKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDETVDFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLSVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGNS
What are the official names of this protein?
Nuclear body protein SP140-like protein.
Protein: S36A2_RAT
Sequence: MSVTKSAGSPQVAATVKLDLVSFPESAKKVQSQDPNPVNGSSSESSEKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRLNKPFMDYGDTVMHGLASSPNTWLQSHAHWGRHAVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNETVVLTPTIDSRLYMLAFLPVLGLLVFIRNLRVLTIFSLLANVSMLVSLVIIGQYIIQGIPDPSQLPLVASWKTYPLFFGTAIFSFESIGVVLPLENKMKDARRFPTILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLPNCWLYQSVKLLYVVGILCTHALQFYVPAEIIIPLAVSQVSKRWALPVDLSIRLALVCVTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVTTYYGEGMSPLTITKDALISILGFMGFVVGTYQALDELIRSGNSLPLSNSTMFIQ
What is the function of this protein?
Electrogenic proton/amino acid symporter with a high selectivity for the small side chains amino acids glycine, alanine and proline, where both L- and D-enantiomers are transported.  Extension of the backbone length, as in beta-alanine and 4-aminobutanoate or methylation of the amino group, as in sarcosine and N,N-dimethylglycine, are also tolerated but decrease transport efficiency.  A free carboxyl group is preferred.
What are the official names of this protein?
Proton-coupled amino acid transporter 2, Proton/amino acid transporter 2, rPAT2, Solute carrier family 36 member 2, Transmembrane domain rich protein 1, Tramdorin-1.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. Recycling endosome membrane.
Protein: Y2_SOCMV
Sequence: MSRLEKIYTNKENPLKDFLDEVEQNDEEMRTVDFNPNKPALPYKKKAIVFPKNFPSETHYNNGVPIGKQLNLGGSVQQVIGGINTILEVLSFLCLRQLPIVASSSHEQLENSKEFKNELQNHLTKITEQLEINRKSIIKDQTVKEDLNKKQYETLYALQEKLLNMLAEKQSSNELKNLERRLDEKIKIIEQQLSEIKLMLS
What are the official names of this protein?
Uncharacterized protein 2.
Protein: CNEP1_CAEBR
Sequence: MTSFAQTVFYVLAGLFNVFLLYFRKTNRAYCKYQVVKYHSNIPMSPLTTHRLLTVKRKILVLDLDETLIHSHHDGVLRQTVKPGTPSDFTIRVVIDRHPVKFSVHERPHVDYFLTVVSQWYELVVFTASMEVYGSSVADKLDRGRGILKRRYFRQHCTMEVGGYTKDLSAIHPDLSSICILDNSPGAYRKFPHNAIPIPSWFSDPNDTCLLNLLPFLDALRFTSDVRSVLSRNMQVLPETQTVQYY
What is the function of this protein?
Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases.  Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels.  May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics.  May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity).
What are the official names of this protein?
CTD nuclear envelope phosphatase 1 homolog, CTDNEP1, Serine/threonine-protein phosphatase dullard homolog, Small C-terminal domain phosphatase-like phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the dullard family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PAND_CAMJJ
Sequence: MNITLLKSKIHRANVTEARLDYVGSISIDEKLLQASGILEYEKVQVVNVNNGARFETYTIATQEEGVVCLNGAAARLAEVGDKVIIMSYADFNEEEAKTFKPKVVFVDENNTATKITNYEKHGAIF
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_SULIL
Sequence: MGKNLLQQRAGKGSPTFRSPSWLRIGKVRYPNIFGHLVGKVIDIVHNPGMNAPVAIIKLENGTKFLTQAIQGLVINQKIEFGKGSPIANGNVIEIGDAPEGTIVCNVEENFGDGGKYARSAGSYAVVVGKSGDKVLIKLPSDKIKAVSNKARATVGVVAGGGVVEKPLLKAGANYWKYKVKAKKWPIVRGVAMNVVDHPHGGGLHQSVSRPSTVSRNAPPGRKVGHIAARRTGRKEGK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS16_HUMAN
Sequence: MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:23636399).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
40S ribosomal protein S16, Small ribosomal subunit protein uS9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: PSA_PYRAB
Sequence: MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVKEKEEDYSELDSHY
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PsmA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYNS_ASPOR
Sequence: MSLATLDTSQHPNLPSASATLFKAKAAKKFSFEQIAQHIGRNEVATAAIFYGQAKASPEDITNLASLLGIPQEVLEDQLNGFPDRGKSVEMPPKEPLIYRLYEIVQNYGYAYKAVLNEKFGDGIMSAISFSTKVEKETDADGNNWAVITLRGKWLPFSRF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: TTH_ACIAM
Sequence: MNLKILVGLFILGIIILSAMTFLNFTTIVAQDKGDQQPKGPIVYTYTEYNGTYFPHILTVVYYPCNATCSNLGFPSVWPVSNENQCHNAVVNTTCQALIEGVDWQLPLLNYVGGVAIPLSTPPCKLPWAQQLGVKGALVYYTQMVGEPLGVTLACGLLYATEDSMPGSITAINPVTGKIVWMANGLAGPAMNNPVVWHGIVYVSVGGVCFTFSQFVHFEDHQYCKIHRGRCGAVYAFNATNGQLLWMRFTYGEAMPAPAIYDGILAYVTGGGCFVGVNATTGQTLWVDHFPGFIANMASVNYYVLPNGTPLFIAGFTYTAPPYGYIIAVNGLNGHEAWNATMPAPYVGANTGLGDVAPAVDQQLGIVVDNDIANFSNGYVDMVTFALNATNGKPLWAVNTGRGPIPPAYKGGMPLIVGNVVYDGNPSLGTVNAICIKTGKILWSTKLPCLQTPPKFPGGPRGSPTYYHGLLWVSAGQYVYVINPKNGDILTFYWIGGRLGIMNPVIAGNTMFLSNSYGWIVAIPLSQIYPAYIYY
What is the function of this protein?
Catalyzes the hydrolysis of tetrathionate to generate elemental sulfur, thiosulfate and sulfate.
What are the official names of this protein?
Tetrathionate hydrolase, 4THase, TTH.
What is the protein family that this protein belongs to?
Belongs to the tetrathionate hydrolase family.
What are the subcellular locations of this protein?
Cell surface. Note=Associated with the S-layer in the pseudo-periplasmic space.