PharMolix/UniProtQA huggingface dataset:
Protein: SYT_STAAM
Sequence: MEQINIQFPDGNKKAFDKGTTTEDIAQSISPGLRKKAVAGKFNGQLVDLTKPLETDGSIGIVTPGSEEALEVLRHSTAHLMAHAIKRLYGNVKFGVGPVIEGGFYYDFDIDQNISSDDFEQIEKTMKQIVNENMKIERKVVSRDEAKELFSNDEYKLELIDAIPEDENVTLYSQGDFTDLCRGVHVPSTAKIKEFKLLSTAGAYWRGDSNNKMLQRIYGTAFFDKKELKAHLQMLEERKERDHRKIGKELELFTNSQLVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPMQLDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSYRDPEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDLHYDYARQLQDELKSQGVRVSIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKKHR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_ALKEH
Sequence: MTTQKQLKVTQKRSTVGRIASHKACVAGLGLRRINHSVVVADTPENRGMINKVAYLLEVEEC
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: UPPP_SHEPA
Sequence: MDTFQVIILALIQGLTEFLPISSSAHLILPAQLLGWEDQGLSFDVAVNTGSLLAVVMYFRREILSMFTAWTGSVVSRKQTDESKLAWWIILATIPAVIIGFSAKDFIETHFRSIEVIAATTIIFGLLLWWADKMQRQGLNEFQVGWKKALVIGIAQAMALIPGTSRSGATITAALMLGLSREAAARFSFLMSVPVSLGAAILVTKDLLSSGQVIDYQALGLGILVSFIAAYICIHYFLKIISKMGMTPFVIYRLALGAVLCWIIFL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLMM_STAAC
Sequence: MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIALDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: PXR1_PICGU
Sequence: MGLAGTKVKQRFGLDPRNTSWSNDKSRFGHRYLESMGWAPGKGLGLVEHATTTHVKVSVKDDTVGLGAKLAKRSGTDDLETDSSGLDDFQRILGRLNGRGREVDEALEQKRKDNIINGKWGMHFIKGEVLCSTWDRKSKSHMLKTALEDESEVNFKSSKKRRQSGSEPSRDSTSHAKRMRGDESKKSTRDQSKQERKEKKIKTEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKERDYGNRASPVEPRKHDQISNVGRLSARAKYIKQKRASVMDAKALNEIFMISK
What is the function of this protein?
Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.
What are the official names of this protein?
Protein PXR1, PinX1-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the PINX1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DTD_PORG3
Sequence: MRVVIQRVTEASVSIRGALHSRIGQGVLILVGIEDRDGESDIELLTSKISNLRIFDDSEGVMNLSVKDINGEALVVSQFTLMGSTRKGNRPSYIKASRPEIAIPLYESFCNSLSAKLGKAVRQGVFGADMQVALVNDGPVTILIDTHNKE
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPB35_MYCTO
Sequence: MNEVSIRTLNQETSKVLARVKRGEEINLTERGKVIARIIPASAGPLDSLISTGSVQPARVHGPAPRPTIPMRGGLDSGTLLERMRAEERY
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Neutralizes the effect of cognate toxin VapC35 (By similarity).
What are the official names of this protein?
Antitoxin VapB35.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: VSP1_GLOHA
Sequence: MVLIRVLANLLILQLSYAQKSSKLVIGGDECNINEHRFLVALYTSRTLFCGGTLINQEWVLTAAHCNMEDIQIKLGMHSKKVPNEDEQKRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSAHIAPLSLPSSPPSVGSDCRTMGWGRISSTKETYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGGKDTCVGDSGGPLICNGQSQGIASWGDDPCAQPHRPAAYTKVFDHLDWIENIIAGNTDASCPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease pallabin, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NAC2_ARATH
Sequence: MSELLQLPPGFRFHPTDEELVMHYLCRKCASQSIAVPIIAEIDLYKYDPWELPGLALYGEKEWYFFSPRDRKYPNGSRPNRSAGSGYWKATGADKPIGLPKPVGIKKALVFYAGKAPKGEKTNWIMHEYRLADVDRSVRKKKNSLRLDDWVLCRIYNKKGATERRGPPPPVVYGDEIMEEKPKVTEMVMPPPPQQTSEFAYFDTSDSVPKLHTTDSSCSEQVVSPEFTSEVQSEPKWKDWSAVSNDNNNTLDFGFNYIDATVDNAFGGGGSSNQMFPLQDMFMYMQKPY
What are the official names of this protein?
NAC domain-containing protein 2, ANAC002.
What are the subcellular locations of this protein?
Nucleus.
Protein: COMM_HAEIN
Sequence: MSLAIVYSRASMGVQAPLVTIEVHLSNGKPGFTLVGLPEKTVKEAQDRVRSALMNAQFKYPAKRITVNLAPADLPKEGGRFDLPIAIGILAASDQLDASHLKQFEFVAELALTGQLRGVHGVIPAILAAQKSKRELIIAKQNANEASLVSDQNTYFAQTLLDVVQFLNGQEKLPLATEIVKESAVNFSGKNTLDLTDIIGQQHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGLLPEMTDLEAIETASVTSLVQNELNFHNWKQRPFRAPHHSASMPALVGGGTIPKPGEISLATNGVLFLDELPEFERKVLDALRQPLESGEIIISRANAKIQFPARFQLVAAMNPSPTGHYTGTHNRTSPQQIMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQNTGDRGETSAQVREKVLKVREIQMERAGKINAYLNSKEIERDCKLNDKDAFFLEKALNKLGLSVRAYHRILKVSRTIADLQGEQQIFQPHLAEALGYRAMVRLLQKLSNM
What is the function of this protein?
Induced during competence development.  Not needed for DNA uptake.  May be involved in a recombination step.
What are the official names of this protein?
Competence protein ComM.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.
Protein: QUEC_STRM5
Sequence: MKKAVVLLSGGMDSAAVIAMAQEQGFAVHALSVRYGQRHTSELDAAARVAKAQGVIAHKTVDVDLRSIGGSALTDDIDVPEAGGAGIPVTYVPARNTIMLSLALGWAEVLGANDIFCGVNAVDYSGYPDCRPEFVAAFQALANLATKSGVEGAGIKVHAPLQFLSKGQIVSEGVRLGVDFGLTVSCYNADANGAACSHCDACRLRAQGFTEAGVADPTLYA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PNP_THEYD
Sequence: MEVELEIKGKKLVLQTGIFAKQTNGSVLAKYGDTYVLCTVVAEKTPKEGLDFVPLTIDYQEKAYSAGKIPGGFFKREGKPTDREILVSRLIDRPVRPLFPDGFNYETQGIASVLSYGDENIADILSIIGISSALTISDIPFNGPVAAVRVGMVEEEFILNPDNDEAEKSILNLVVAGTEEAVTMVEGGAAECSEETLVEALKFAHTHIKKIIALQKKLQQLSGKPKREIISLNGDEEIQKAILNIIGGKIENALFLPKKVERQQALDELLNECLQNLNTEEFRQKLYGNFDKDISLEITNAFDKVIKKFMRESIVKKGIRADGRKSDEIRPITCMIGILPRVHGSALFTRGETQALVATTLGTSEDEQKVDSLEGEIFKTFMLHYNFLPFSVGEVKPLRAPGRREIGHGYLAERALSYVIPSKDEFPYTIRVVSDILESNGSSSMATVCGATLSLMDAGVPIKAPVAGVAMGLIKEGDKTVVLTDILGMEDHYGDMDFKVAGTEKGITAFQMDVKISGISYEIFKKALKQAKQARLFILKKMAETISEPKKELSLYAPRIYKIQVKPEKIRDIIGTGGKVIKGIIEETGVKIDIEDKEGIVKIASSNESAAQKAIEIIKGITQEAELGRIYMGKVTRIVDFGAFVEIMPGVEGLLHISQIADKRIQKVSEVLKTGEQIPVKVIEIDELGRVRLSRKEALREIENRTATKT
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_METFK
Sequence: MKVYYDKDADLSLIKKLKVTIVGYGSQGHAHAQNLKDSGVNVTIGARKEGSSFAKAVNAGHEVKEIKEAVTGADVVMVLLPDETMAEIYHAEIEPNLKKGAALAFAHGFNIHYNQIVPSKDLDVIMIAPKGPGHTVRSEYLKGGGVPSLIAVYQDASGKAKDIALSYAAANGGTKGGVIETNFREETETDLFGEQAVLCGGAVELVKAGFETLVEAGYAPEMAYFECLHELKLIVDLMYEGGIANMNYSISNNAEYGEYVTGPRVIADQARAAMKECLKNIQNGDYAKQFILEGRTGYPSMTARRRLNAAHPIEQVGSQLRAMMPWIAKNKLVDQSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YGWB_SCHPO
Sequence: MGRPLIESSSNDHVANFNRKTKKLIDQALEHYNGRLPEQLENFSFENFVEVLDTESSVVNRVFEVLVREVAGSFRQRKRAHMPRTNTTAQVVQRQLAPSISTVFSRDSNDPLVDDMDQEYIL
What are the official names of this protein?
Uncharacterized protein C8D2.11.
Protein: Y1839_SHEHH
Sequence: MAFWNEKTLAQMSTQEWESLCDGCGKCCLNKLIDDETEQLYYTNAACLLLDNKAGHCQNYEQRFSFVPSCTKVTVDNIESLTWLPDSCAYRRLFMGRELPTWHPLRTGSKEAMILAGMSVAGKVTCETKIRDIEDHIVLWPMKDVE
What are the official names of this protein?
UPF0260 protein Shal_1839.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: FUT2_RAT
Sequence: MASAQVPFSFPLAHFLIFVFVTSTITHLQQRIVKLQPLSEKELPMTTQMSSGNTESPEMRRDSEQHGNGELRGMFTINSIGRLGNQMGEYATLFALARMNGRLAFIPASMHNALAPIFRISLPVLHSDTAKKIPWQNYHLNDWMEERYRHIPGHFVRFTGYPCSWTFYHHLRPEILKEFTLHDHVREEAQAFLRGLRVNGSQPSTFVGVHVRRGDYVHVMPNVWKGVVADRGYLEKALDMFRARYSSPVFVVTSNGMAWCRENINASRGDVVFAGNGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLAGGDTIYLANYTLPDSPFLKVFKPEAAFLPEWVGIPADLSPLLKH
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation (PubMed:11341836, PubMed:11179967).  Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs.  Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition (By similarity).  Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway (PubMed:11179967).
What are the official names of this protein?
Galactoside alpha-(1,2)-fucosyltransferase 2, Alpha 1,2-fucosyltransferase, Alpha 1,2-fucosyltransferase B, Alpha 1-2 fucosyltransferase, Alpha(1,2)FT 2, Fucosyltransferase 2, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2, Secretor blood group alpha-2-fucosyltransferase, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: Y1538_ERWT9
Sequence: MFCVIYRSPQRDQTYLYVEKKDDFSRVPEALLKGFGKPKLAMILPLDGSKKLVGADIKKVKTALREEGFYLQLPPPLESLLKIHLSDANKV
What are the official names of this protein?
YcgL domain-containing protein ETA_15380.
Protein: TRPA_ALISL
Sequence: MDRYQALFAKLAEKNQGAFVPFVTIGDPNPELSYEIMDTLVKAGADALELGIPFSDPLADGPTIQGANIRALNSKTTPIVCFDLIAKIRAKYPETPIGLLVYANLVFANGIDTFYTKCQQAGVDSVLIADVPTNESEEFRTSAIKHNVHPIFIAPPSASDETLETVAKLGGGYTYLLSRAGVTGAETKAGMPVAQLLARLNQFDAPPAILGFGISEPAQVEEAIKAGAAGAISGSATVKIIEQHQDNPAALLDALTAFTSAMKAATQK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: HYPA_HELPJ
Sequence: MHEYSVVSSLIALCEEHAKKNQAHKIERVVVGIGERSAMDKSLFVSAFETFREESLVCKDAILDIVDEKVELECKDCSHVFKPNALDYGVCEKCHSKNVIITQGNEMRLLSLEMLAE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: NQRD_SHEHH
Sequence: MANAKELKQVLTGPIVSNNPIALQVLGVCSALAVTSKMETALVMTIALTVVCAFSNLFISILRNHIPSSVRIIVQMTIIASLVIVVDQVLQAYAYDVAKQLSVFVGLIITNCIVMGRAEAYAMKTPPMMSFMDGIGNGIGYGAILLSVGFIRELFGNGSLFGVEILSKVSDGGWYQPNGLLLLPPSAFFLIGMLIWIIRTYKPEQVEAKG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LTOR4_HUMAN
Sequence: MTSALTQGLERIPDQLGYLVLSEGAVLASSGDLENDEQAASAISELVSTACGFRLHRGMNVPFKRLSVVFGEHTLLVTVSGQRVFVVKRQNRGREPIDV
What is the function of this protein?
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids.  Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag.  Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.
What are the official names of this protein?
Ragulator complex protein LAMTOR4, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR4 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: SDHA_BOVIN
Sequence: MSGVAAVSRLWRARRLALTCTKWSAAWQTGTRSFHFTVDGNKRSSAKVSDAISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMESGECRGVIALCIEDGSIHRIRARNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPAQLAMRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQGVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPSIKPNAGEESVMNLDKLRFANGSIRTSELRLNMQKSMQSHAAVFRVGSVLQEGCEKISSLYGDLRHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGGPRREDFKERVDEYDYSKPIQGQQKKPFEQHWRKHTLSYVDIKTGKVTLEYRPVIDRTLNETDCATVPPAIGSY
What is the function of this protein?
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (Probable).  Can act as a tumor suppressor (By similarity).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, Fp.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GPMI1_METAC
Sequence: MAQARRPLMLIILDGWGYREVEEGNAVLSAGTPNLDRLVKDYPWCLLEASGGAVGLPEGMMGNSEDGHLNIGAGRIVYQNLTRINISIRNGDFFKNPVFLNAISKVKANDSSLHLIGLVSCGGVHSYTPHLHALIKLAKEKGLKKVYIHAFLDGRDVPPKTALGDIKKLNEFCKEHGGAKIATVSGRYYAMDRDKRWDRTKLAYDVLTLGASQYKAPNAETAVSEAYGRGETDEFVKPTVITDHEEKPVATIRDKDSVIFFNFRADRARQLTWAFVKDDFDGFVREKRPKIYFVCMARYDEDLDLPVAFPHEELKNVLGEVLSKQGLTQLRIAETEKYAHVTFFLNGGEEKRYEGEDRCLIPSPKIATYDLKPEMSAYKITDEVVRRIQSGKYDVIVLNFANMDMVGHTGIFEAAVKAVEAVDKCIGRIVEALKEIGGVALITADHGNAEQMIDSKTGEPHTAHTSNPVRCIYFGNGEVKALKKGKLCDLAPTLLELIGIPKPQEMTGKSLLVKE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1, BPG-independent PGAM 1, Phosphoglyceromutase 1, iPGM 1.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: BA17B_METAN
Sequence: MASEMNASPEYTGYRLEVFIAVFTPLTIIAVALRFYARSLTSKKIDSGDWLIIAALVGQIVAGGIAIGAVKQAGVGHHAAYLAETNPETLVAFFKYLVAMSTWYATTEGLAKLAVCILYKRLFPQRGIHMVINTTMLVLVGASVGGGLADLFGCTPFSAHWGTAEEQAAHCIDTEALFVWGSFPNIVTDVVLLVLPMPIVWGLHASVRLRLVLVLTFLFGSIFGELIGGDSGLITSVLRFIAFYNKSSFIDPTFHAVELIIWTVCEPGVYLIAACLLVYRPLLEKIGIPLVGGVSSRGGNRQEPTELAFQKPSRPRNGAVIKSIGSGSISESGFEYIGDDDQRPLRRQGGITATTNVEVTWAAGSAV
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of (2Z,4E,6E,10E)-9-hydroxydodeca-2,4,6,10-tetraenoic acid (BAA), (2E,4E,6E,10E)-9-hydroxydodeca-2,4,6,10-tetraenoic acid (BAB), and (2Z,4E,6E)-octa-2,4,6-trienedioic acid (PBA) (PubMed:33991663).  The highly reducing polyketide synthase Ba17a is sufficent to produce PBA and BAA (PubMed:33991663).  The still to be characterized protein Ba17b leads to an increased production of BAA as well as to the production of the new compound BAB (PubMed:33991663).  BAA does not possess insecticidal activity against G. mellonella larvae, however, both BAA and BAB increase the growth of Candida albicans and BAA can mitigate the fungicidal effects of fluconazole over C. albicans, suggesting that generalist pathogens such as M. anisopliae, can potentially manipulate the yeast microbiota found in arthropods (and anywhere else) by the activity of compounds as BAA and BAB (PubMed:33991663).
What are the official names of this protein?
Polyenoic acids biosynthesis gene cluster protein Ba17b, PKS17 biosynthesis gene cluster protein Ba17b.
What is the protein family that this protein belongs to?
Belongs to the SAT4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RSMH_KLEP7
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSRLGAEGRLLAIDRDPQAIAVAQTIDDPRFSIVHGPFSQLAEYVGERNLTGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEDDIAWVIKTFGEERFGKRIARAIVERNRIQPMTRTKELAEVIAAAMPVKDKHKHPATRTFQAVRIWVNSELEEIEQALKSSLSVLAPGGRLSIISFHSLEDRIVKRFMREQSRGPQVPAGIPMTEAQLKKLGGRELRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1905_PSEF5
Sequence: MKGGMAGLMKQAQQMQEKMAKMQEELANAEVTGKAGGDMVTVVMTGRHDIKRVSIDPSLLEGVSEDDREVLEDLFAAAVNDAVRKIESNSQEKMSGMTAGMQLPPGMKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein PFL_1905.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: STON2_HUMAN
Sequence: MTTLDHVIATHQSEWVSFNEEPPFPAHSQGGTEEHLPGLSSSPDQSESSSGENHVVDGGSQDHSHSEQDDSSEKMGLISEAASPPGSPEQPPPDLASAISNWVQFEDDTPWASTSPPHQETAETALPLTMPCWTCPSFDSLGRCPLTSESSWTTHSEDTSSPSFGCSYTDLQLINAEEQTSGQASGADSTDNSSSLQEDEEVEMEAISWQASSPAMNGHPAPPVTSARFPSWVTFDDNEVSCPLPPVTSPLKPNTPPSASVIPDVPYNSMGSFKKRDRPKSTLMNFSKVQKLDISSLNRTPSVTEASPWRATNPFLNETLQDVQPSPINPFSAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQIDDPDHFGSATLPDDDPVAWIELDAHPPGSARSQPRDGWPMMLRIPEKKNIMSSRHWGPIFVKLTDTGYLQLYYEQGLEKPFREFKLEICHEISEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHTAEREQVIKLGTTNYDDFLSFIHAVQDRLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGIVSKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDILVKGNEIVLRQDIMPTTTTKWIKLHECRFHGCVDEDVFHNSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTATSVNGAEVEVQSWLRMSTGFSANRDPLTQVPCENVMIRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSTSVSGSEPVMRVTLGTAKYEHAFNSIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANHVNVEFSMPTTSASKASVRSISVEDKTDVRKWVNYSAHYSYQVALGSIWLMLPTPFVHPTTLPLLFLLAMLTMFAW
What is the function of this protein?
Adapter protein involved in endocytic machinery.  Involved in the synaptic vesicle recycling.  May facilitate clathrin-coated vesicle uncoating.
What are the official names of this protein?
Stonin-2, Stoned B.
What is the protein family that this protein belongs to?
Belongs to the Stoned B family.