PharMolix/UniProtQA huggingface dataset:
Protein: SYT_STRA5
Sequence: MIKITFPDGAIREFESGITTFEIAQSISNSLAKKALAGKFNGQLIDTTRAIEEDGSIEIVTPDHEDALGVLRHSAAHLFAQAAKRLFPDLCLGVGPAIQDGFYYDTDNKSGQISNDDLPRIEEEMKKIVKENHPCIREEISKEEALELFKDDPYKVELISEHAEDGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNAMMQRVYGTAWFDKKDLKAYLKRREEAKERDHRKLGKELDLFMVNPEVGQGLPFWLPNGATIRRELERYIVDKEIASGYQHVYTPPMASVEFYKTSGHWDHYREDMFPTMDMGDGEEFVLRPMNCPHHIEVYKHHVHSYRELPIRIAELGMMHRYEKSGALTGLQRVREMTLNDAHIFVTPEQIKDEFLKALNLIAEIYEDFNLTDYRFRLSYRDPEDKHKYYDNDEMWENAQAMLKEAMDDFGLDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEEHRPIMIHRGGISTMERFTAILIETYKGAFPTWLAPQQVSVIPISNEAHIDYAWEVARVLKDRGIRAEVDDRNEKMQYKIRAAQTQKIPYQLIVGDKEMEEKAVNVRRYGSKATETKSIEEFVESILADIARKSRPDEVK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_SHEB5
Sequence: MRTENTATLNLIWGALILEELARLGVQHVCMAPGSRSTPLTLAAAQQTKLQRHLHFDERGLGFMALGLAKASRAPVAIITTSGTAVANLYPAIVEAWLTHVPLIVLSGDRPPELLGCGANQAIVQPGIFANYATQVNLPTPDAHIAPQALLTTVDEAVANQTRPVHINCMYREPLYPSELSGVILDAESPYLKPLQTWLQLARPYTQYGKSKQLSSPSDDAIMRFVHGKGVIVVGTLTPEQDPQQLIALSQKIGWPLLTDAQSQLRQHPAAIGNIDQLLQHPKARNLLQEADRVLVFGGRLLSKRVIGYLAEQNWHSYWQVLPEQDRLDPSHNAKHIWHANAEQFAALNWYRSSSANWANTLITYNDELHNLFVRNIDQGEFGEAQVIRAIANTRPLEQQLFIGNSLPVRLYDMYAPVSCCTATTYTNRGASGIDGLLATACGIAAHEGKPTSLIIGDLSQLHDLNSLAIAKGLSSPLVIVILNNDGGNIFNLLPVPNEQVRSEYYRLSHGLEFGYAAAMFNLPYNQVDNLADFQDSYNEALDFQGASIIEVNVSQNQASDQIAALNLWVKQS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: NHAA_DESHY
Sequence: MSTQKKTINFLQEFSIPLILGVLIALVWANLAPENYHHFVHNEIIGHISLHFFVNDIFMVFFFAMAAIEITQSLLPGGSLNPLKRAINPLMATLGGVLGPALVFLGLNALIGSPEFARGWGIPTATDIALAWLVARVVFGAQHAAVSFLLLLAIVDDGIGLMIIAFFYPDPANPVAPLWLLLTVAGMLVAYLLRRKNVQSYWPYIILGGILSWAGLYLAHIHPALALVFIVPFLPHPPREEFGLFEDDPQDHSTLKTFEHEWKIFVDFGLLLFGLTNAGVEFSEINTLTWLVLIALVGGKTIGIFLMGSLATVIGFPFPKGMGYKELLVAGVIAAMGLTVALFVSGVAFIDPGLQGAAKMGALFSAVAAVIAFALGKVLGIKKVKDTQA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SLYX_ACTP2
Sequence: MTTENDLLNRIAELETKVAFQEITLEELNQALIHHQLALDKLQTQMRHFAEKLKGAQVSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: SCPB_BREBN
Sequence: MDYDKLKGVIEGLLFISGDEGIDAKEISEITEVTEEEVIDLIEDMKADFRRAGRGIQIVEVAKAYQLTTLPEHVPYFERLATSPGQSTLSQAALETLAIVAYKQPLTRSEIEEIRGVKCEKALNTLLSKQLIREAGRAEGIGRPILYATTKEFLEHFGLRELGDLPEPPVNLDIEEARLEASALFGKAEEATND
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: HFQ_ECO81
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: T2R41_MOUSE
Sequence: MLPTLSVFFMLTFVLLCFLGILANGFIVLMLSREWLLRGRLLPSDMILFSLGTSRFFQQCVGLVNSFYYFLHLVEYSGSLARQLISLHWDFLNSATFWFCTWLSVLFCIKIANFSHPAFLWLKWRFPALVPWFLLGSILVSVIVTLLFFWGNHTIYQAFLRRKFTGNTTFKEWNRRLEIDYFMPLKVVTMSIPCSLFLVSILLLISSLRRHSLRMQHNTHSLQDPNVQAHSRALKSLISFLVLYAVSFVSMIIDATVFISSDNVWYWPWQIILYFCMSVHPFILITNNLRFRGTFRQLLLLARGFWVA
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 41, T2R41, T2R12, T2R26.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYY_METMA
Sequence: MDRLELIKRNVQEIVTEEELEGLLNKKETPRAYVGYEPSGKIHMGHVLTVNKLIDLQKAGFKITVLLADVHAYLNRKGTLEEVRKIADYNRRCFIALGLDEEQTDFVYGSDFQLGAEYMLNVLKLSRAVTLNRAKRSMDEVGRAMDDPTVSQMVYPLMQAIDIALLEVDVAVGGIDQRKIHMLARENLKSLGFETPICIHTPILLGLDGTKMASSKDNFISVDDTEEEIYRKFKKAFCKMGDVEENPILALFRYHIFPRYETIVIERPEKFGGNLVYNSYSEMESGFAEEKVHPMDLKNSAAKYINEILDPVRKVLL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_RHIPM
Sequence: MSLTYMNMFLAFTISLVGLLMYRSHMMSALLCLEGMMLSLFVMMTITILNIHLTLASMTPIILLVFAACEAALGLSLLVMVSTTYGMDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MLAA_ECOLI
Sequence: MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADGFYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQAIQDDLKDIDSE
What is the function of this protein?
Involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane.
What are the official names of this protein?
Intermembrane phospholipid transport system lipoprotein MlaA.
What is the protein family that this protein belongs to?
Belongs to the MlaA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SFSA_SHEFN
Sequence: MKFTPELESGVLIKRYKRFLADIMLPNGQEITIHCPNTGSMKNCLFPGEKVWFSTSDNPKRKYAHTWELMQTDQQHYIGINTGRANALAEEAINRQVITELLGYEHLKREVKYGSENSRIDILLTSQNRPECYIEVKSCTLLEDQMGYFPDAVTTRGQKHLRELIHMVELGHRAVLLFVVQHSAITSVKPARHIDPHYADLLEQAVANGVEVLAYKTALSPQGSLITSACKVML
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RBL_CAJCA
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPQYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPISYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALFKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIIMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHVHSGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKAIKFEFPAMD
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL10_LISMH
Sequence: MSKVLEAKQSAVEEIKTKLSASASTVIVDYRGLNVGEITELRKQLRDAGIEFKVYKNSLTRRAVEANGYEGLEGALTGPNAIAFSNEDVVAPAKILNDFAKDHEALEIKAGVIEGKVASLEEIKALATLPSREGLLSMLCNVLQAPVRGLAIATKAVADQKEGQEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL10_STRT2
Sequence: MSEAIIAKKAEQVAIVADKMKAAASIVVVDSRGLTVDQDTVLRRNLRESGVEFKVIKNSILSRAAEKAGLEDLKKLFVGPSAVAFSNEDVIAPAKVISEFAKGAEALEIKGGVVDGAITSVEEINALASLPNKEGMLSMLLSVLQAPVRNVAYAVKAVAESKEDGAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: HIS4_SHEHH
Sequence: MIIPAIDLIDGQVVRLYQGDYEQQTTFNLSPLDQLKSYQAQGANLLHIVDLTGAKDPTKRQTALISELVNHLDTPIQVGGGIRTEAQLNELLEIGVSRVVIGSLAVKEPELVKSWFEKYGNEAICLALDVNINEQGEKIVAVSGWQTGGGKSLESLVEEFKTVDLKHALVTDISRDGTLQGANTELYREIAASYPEIQWQASGGIATLADVNAVKDSGADGIIIGKALLIKQFSVKEAIACWPNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCEI_ECOLI
Sequence: MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLGYSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKYPQATFTSTSVKKDGDELDITGDLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGKIKLKDFNIKTDLGPASQEVDLIISVEGVQQK
What are the official names of this protein?
Protein YceI.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: ACHG_HUMAN
Sequence: MHGGQGPLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQEDGQTIEWIFIDPEAFTENGEWAIQHRPAKMLLDPAAPAQEAGHQKVVFYLLIQRKPLFYVINIIAPCVLISSVAILIHFLPAKAGGQKCTVAINVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLLVVTILIVVNAVVVLNVSLRSPHTHSMARGVRKVFLRLLPQLLRMHVRPLAPAAVQDTQSRLQNGSSGWSITTGEEVALCLPRSELLFQQWQRQGLVAAALEKLEKGPELGLSQFCGSLKQAAPAIQACVEACNLIACARHQQSHFDNGNEEWFLVGRVLDRVCFLAMLSLFICGTAGIFLMAHYNRVPALPFPGDPRPYLPSPD
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Gamma/CHRNG sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: HIS3_HYDCU
Sequence: MSQQLTFKQLEKAQQGDSFDWEAVKKQVKYDDNGLIPAIAQQFDSKEVLMMAWMNEAALQETLETGRVCYWSRSRQSYWRKGEESGQIQLLKDLRFDCDGDAILLLVDQTGPACHTGRKSCFYTAIHDHQAKILTNPIIDPEALYKK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTIA_ECOLI
Sequence: MKEFLFLFHSTVGVIQTRKALQAAGMTFRVSDIPRDLRGGCGLCIWLTCPPGEEIQWVIPGLTESIYCQQDGVWRCIAHYGVSPR
What are the official names of this protein?
Uncharacterized protein YtiA.
Protein: APOC1_PHOVI
Sequence: MRLFLSLPVLVVVLAMVLEGPAPTQAAPEISSTLGRIPDKLKEFGNTLEDKARAAIESMKQSDIPAKTRNWFSETFNKVKEQLKTAFS
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification.  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FMT_METI4
Sequence: MMRVVFIGTGDFGVPSLEAIALDGRYTIPAVVTQADKPLGRQKEVIPSPIKRTALKHHIWVFQPENINSAGSIQQIQFLKPDLLVVCDYGQILSKAVLEIPSIGALNIHGSLLPKYRGASPIQAAIMNRDKETGVTVIWMDEGIDTGDILMSDKLLVRSTDTAETLHHRLAELGARLIIQSLEAIRAGKAPRIPQNNALASYAKKIKKEQALIDWTKDRHEIDAMIRAFNPWPVAFTTVWIGGEKKILKIFKVIISHRAKGMPGEVVRIDRHGILVAAGRSGGLLLREVQLEGRKRMHAADFARGARLAIGTVLGQKDEQ
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: OBG_ROSDO
Sequence: MKFLDLCKVYIRSGAGGGGCVSFRREKYIEYGGPDGGDGGTGGSVWAEAVDGLNTLIDFRYQQHFFAKNGQPGMGRQRTGKDGDDIVLRVPVGTEILDEDQETVICDLTEVGQRVQLARGGNGGFGNLHFKSSTNQAPRRSNPGQDGVERTLWLRLKLIADVGLLGLPNAGKSTFLAATSNARPKIADYPFTTLHPNLGVVGVDNTEFVVADIPGLIEGASEGRGLGDLFLGHIERCAVLLHLFDGTSETLIEDYHTIIGELEAYGVGLADKPRITVLNKIDALDEERRAMALKQLNNVCGGGVMAMSGVAGDGVTDVLRKLRGEISDEPLRHKPVEEKEPWRP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLGB_STAAU
Sequence: MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
What is the function of this protein?
Toxin that seems to act by forming pores in the membrane of the cell.  Has a hemolytic and a leucotoxic activity.  Promotes host AMFR-mediated inflammation by mediating 'Lys-27'-linked ubiquitination of TAB3, TAK1-TAB3 complex formation and phosphorylation of TAK1/MAP3K7.  In turn, activates host NF-kappa-B signaling pathway.
What are the official names of this protein?
Gamma-hemolysin component B, H-gamma-1, H-gamma-I.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: V1R40_MOUSE
Sequence: MNKANMLRTDKDMQIILFSEVSVGISANSILFIAHVCMILGENRPKPIDLYIAFLSLTQLMLLITMGLIAVDMFLSQGIWDSTTCQSLIYLHRLLRGLSLCATCLLNILWTITLSSRSFCSTKFKHKSPHHISGAFIFFCVLYMSFSSHLFISIIATHNLTSENFIYVTQSCSLLPLSYSRTSMFSAPMAIREAFLVSLMALSSGYMVALLWRHKKQAQHLHSTSLSSKASPEQRATRTILLLMSFFVVLYILENAVFYSRIKFKDGSILYCVQIILCHSYATVNPFVFICTEKHIIKFWESKCGRIVNI
What is the function of this protein?
Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
What are the official names of this protein?
Vomeronasal type-1 receptor 40, Vomeronasal type-1 receptor A11, Vomeronasal type-1 receptor B7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RT26_DROME
Sequence: MLRAGCQLLTQSTLPTGKTVGNSFALEFVRWRRKPRWLPVAKSKMFRVPERKKQSEEERTELMRLHNQYKTQLRSVRQFLREEVVRHEETSTADHIVLTPEQEEAEFQKCLDANAAWNAAIAKERDQRLAKKREEKVAYIQERLEAQQLREEERKEQANQRVLLEIERSKNYITRENLDAAIETALANPVDHNFAIDMAGNLYHGRSTSQLPDATPEPNQQVLSN
What are the official names of this protein?
Probable 28S ribosomal protein S26, mitochondrial, MRP-S26, S26mt.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS26 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SPDLY_XENTR
Sequence: MEESETVLKLRLQLKEAEEERIKAAQYGLELLESQSDLQNQLEEQRNEMTSTIENLEQEKYSLQREVELKNRMLESLTSECENIRQQQKLCLEQLQEQLERNHHRELSEIKDKLEKLKAELDEARLSEKQLKHKLEYQSEVLANKSEELRMMSERVHETMSSEMLTLQLEKTELESAKANLEQEVNELQYREQQLLLTNGTQSRQLERLQDEKEDREKEAVGYFKALEKAREANQDLQAQLDIALQQAQDPNSKGNSLFAEVEDRRAEMERQLISMKVQFQSLQKQHAFSRQQMHRMKVQIATLLQLKGSQSDPEQLERLQAMVAQKNSEFETLVMKVRQLEKSQQICENGPVANSSDGLGQGDETYYVDLLKMKLVNSSKEIEKIKDELSLQRMKALAESQRVLDLERKLFANDRHLKLSQGENMKLRVNLDEMKMKYEPDEIAKIRTQKRRKEQLPLDCAIDNTSATVTSGSQAHGLSDAIPEDMCPAESTVHRNLLKEDSSLSTKEQDLSSVAVKPIEPANGQPPKERKRVRIVENENDNQDINKRNTNNCSVTSTSPRSASEESTSESKRFDEEQEKRKQERKSRLRAPPVLHVPSKPAATTQCPQQ
What is the function of this protein?
Required for the localization of dynein and dynactin to the mitotic kintochore.  Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex.  May act as an adapter protein linking the dynein motor complex to various cargos (By similarity).
What are the official names of this protein?
Protein Spindly, Coiled-coil domain-containing protein 99, Spindle apparatus coiled-coil domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the Spindly family.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore.
Protein: ARNE_SHIFL
Sequence: MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLALACLGLAMMLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2782_BACCZ
Sequence: MKIYVDADACPVKDVIIFEATKAEIPVTLVTSFSHYSNAEQPKGVETIYVDSGADAADYRIMQLAKKEDLIVTQDYGLASLALAKGCIVLHHKGYKYTNENIDQLLQTRYLSAMVRKSGKRTKGPKPFTAEDKEKFRALFKSIIAL
What are the official names of this protein?
UPF0178 protein BCE33L2782.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: O52K2_HUMAN
Sequence: MSASNITLTHPTAFLLVGIPGLEHLHIWISIPFCLAYTLALLGNCTLLLIIQADAALHEPMYLFLAMLAAIDLVLSSSALPKMLAIFWFRDREINFFACLAQMFFLHSFSIMESAVLLAMAFDRYVAICKPLHYTKVLTGSLITKIGMAAVARAVTLMTPLPFLLRCFHYCRGPVIAHCYCEHMAVVRLACGDTSFNNIYGIAVAMFIVVLDLLLVILSYIFILQAVLLLASQEARYKAFGTCVSHIGAILAFYTTVVISSVMHRVARHAAPHVHILLANFYLLFPPMVNPIIYGVKTKQIRESILGVFPRKDM
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 52K2, Olfactory receptor OR11-7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS8_CHRVO
Sequence: MSMHDPISDMLTRIRNGQHASKVKVSMPSSKLKIALAQVLKEEGYIEDFAIAGEEKKPVLDIQLKYYAGRPVIERIERVSRPGLRVYKGSTEIPKVMNGLGVAILSTSKGVMTDRKARAAGIGGELLCVVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: Y2450_STAHJ
Sequence: MERIVITGALGQIGTELVLKCREIYGNDNVLATDIREPEEDSPVNNGPFEVLDVTNREAMMAIVENFKADTLMHMAALLSATAEKNPLLAWDLNMGGLMNALETARTYELHFFTPSSIGAFGDSTPKKDTPQNTIQQPTTMYGVNKVAGELLCQYYFTKFGVDTRSVRFPGLISHVKEPGGGTTDYAVEIYFEAVRKGRYTSYIAKDTYMDMMYMDDAIDAIIKLMEADSDKLVTRNGYNLSAMSFEPEQIKAEIQKHYPGFALDYEVDPVRQAIADSWPDNIDTSYSRKEWGFNPKYDLAGMTELMLKAIEEKEQNK
What are the official names of this protein?
Uncharacterized epimerase/dehydratase SH2450.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.