PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_PHOPR
Sequence: MSHFEAFMLALIQGLTEFLPVSSSAHLILPSEILGWPDQGLAFDVAVHVGTLAAVILYFRKEVVTLLSAWITSIFKGKHTAESKLTWMIALATIPACIFGLFMKDFIELYLRSAWVIATTTIIFAILLWWVDKHSEHKFDEYQTGWKRALFIGLAQAAAIIPGTSRSGATMTAALYLGFTREAAARFSFLMSIPIIVLAGSYLGLKLVTSGVPIDFSALSIGIAVSFISAYACIHAFLKLVTRVGMMPFVIYRLVLGFGLIAFLLSK
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS21_ACIAC
Sequence: MTTIRVKENEPFDVALRRFKRTIEKLGLLTDLRAREFYEKPTAERKRKKAAAVKRHYKRVRSMQLPKKLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: VIAA_ECOLC
Sequence: MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKAAITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRLNSPWAEQARQLVDANSAITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQLGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELATLGITELEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGGTDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVAMSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: ASK8_ARATH
Sequence: MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex.  The functional specificity of this complex depends on the type of F-box protein.  In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity).
What are the official names of this protein?
SKP1-like protein 8, AtSK8.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HMGR1_PANGI
Sequence: MDVRRRLPPKLRRPLPITESSHHHRKTPFPADVDRSPSPTPKASDALPLPLYLTNGIFFTLFFSVAYYLLHRWRDKIRSSTPLHIVTLSELAAIVSLIASFIYLLGFFGIDFVQSFVSRADVDVDIDVEPDILEADRRPCSKLMDQPPPPPVVMSSEEDEEIVKSVVSGKTPSYSLESKLGDCYRAASIRREAVQRTTGRSLLGLPLDGFDYESILGQCCEMPIGYVQIPVGIAGPLLLNGCEYVVPMATTEGCLVASTNRGCKAIYACGGATGILLKDGMTRAPVVRFSTAKRASDLKFFLEDPLNFDTLAVVFNKSSRFARLQSIQCSMAGKNLYIRFCCSTGDAMGMNMVSKGVQNVLEFLQSDFPDMDVIGISGNFCSDKKPAAVNWIEGRGKSVVCEAIITDDVVKKVLKTTVPALVELNMLKNLAGSAVAGALGGFNAHAANIVSAVFIATGQDPAQNIESSHCITMMEAINNGKDLHISVTMPSIEVGTVGGGTQLASQSACLNLLGVKGANKESHGSNSRLLATIVAGSVLAGELSLMSAIAAGQLVRSHMKYNRSSRDMSKIGS
What is the function of this protein?
Catalyzes the synthesis of mevalonate, the specific precursor of all isoprenoid compounds present in plants (By similarity).  Component of the triterpene saponins (e. g.  ginsenosides or panaxosides) and phytosterols biosynthetic pathways (PubMed:24569845, PubMed:29378087).  Promotes triterpenes accumulation in roots (PubMed:24569845).
What are the official names of this protein?
3-hydroxy-3-methylglutaryl coenzyme A reductase 1, HMG-CoA reductase 1, Hydroxymethylglutaryl-CoA reductase, PgHMGR1.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Plastid, chloroplast membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein. Note=Localized in intracellular vesicles.
Protein: MAOM_SOLTU
Sequence: MAIFSNQMRLSSTLLKRLHQRVAAAVNSSSSRNFTTTEGHRPTIVHKRSLDILHDPWFNKGTAFSFTERDRLHIRGLLPPNVMSFEQQIARFMADLKRLEVQARDGPSDPYVLAKWRILNRLHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFSAEDRGEMMSMVYNWPADQVDMIVVTDGSRILGLGDLGIQGIGIAIGKLDLYVAAAGINPQRVLPVMIDVGTDNENLLKDPLYLGLQDHRLDGEEYIEVIDEFMEAVFTRWPHVIVQFEDFQSKWAFKLLQRYRNNYRMFNDDIQGTAGVAIAGLLGAVRAQGRPMIDFPKMKIVVAGAGSAGIGVLNAARKTMARMLGNTEIAFESARSQFWVVDAKGLITEARENVDPDARPFARKIKEIERQGLSEGATLAEVVREVKPDVLLGLSACGGLFSKEVLEALKHSTSTRPAIFPMSNPTRNAECTPEEAFSILGENIIFASGSPFKDVDLGNGHVGHCNQANNMFLFPGIGLGTLLSGSRIVSDGMLQAAAECLAAYITEEEVLKGIIYPSISRIRDITKEVAAAVVKEAIEEDLAEGYREMDSRELRKLDEAQISEFVENNMWSPDYPTLVYKKD
What are the official names of this protein?
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: K1C39_RAT
Sequence: MDTKGSTVTISSSTPPQNCSGNTNVRTNSSNKSCYHDVQSTGHALQTPQGQGCRPSPCLYRCPNYLIRTYSFHPCPDDCSRCSDGINSHEKETMQILNERLASYLEKVRMLEGENADLEDKIQEECSKTLPILCPDYLSYYTTIEQLQQKILCTKAENSRLVSQIDNTKLAADDLRAKYEAELSLRQLVEADANGLKQILDALTLSKADLEARVQSLTEELLCLKTNHEEEINSLQCQLGDRINIEVTAAPSVDLNQILQKMRCQYESIVETNRKDVEEWFNTQMEELNQQVVSSSQQQQCCQKDIIELRRTISALEVELQAQHRMRDSQECILAETEARYTALLAQIQSLIHNLEAQVAEIRSALQRQNQEYEVLLDIKSRLECEIATYRSLLESLDGRLPCNPCTTTWEPSCQARAMECLTPVYTSISLPGIHKPCRASGPPSRILVKICTITKEIKDGKVISSHEHVQPCYITRPAKV
What is the function of this protein?
May play a role in late hair differentiation.
What are the official names of this protein?
Keratin, type I cytoskeletal 39, Cytokeratin-39, CK-39, Keratin-39, K39, Type I hair keratin Ka35.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: XKZB_BACSU
Sequence: MYYAMHELHYSPSQLLELYEAPKHFKALLFGLIGYKLDLLEKESRRGGN
What are the official names of this protein?
Uncharacterized protein XkzB.
Protein: INSI1_HUMAN
Sequence: MPRLHDHFWSCSCAHSARRRGPPRASAAGLAAKVGEMINVSVSGPSLLAAHGAPDADPAPRGRSAAMSGPEPGSPYPNTWHHRLLQRSLVLFSVGVVLALVLNLLQIQRNVTLFPEEVIATIFSSAWWVPPCCGTAAAVVGLLYPCIDSHLGEPHKFKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAMGVPEKPHSD
What is the function of this protein?
Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR (PubMed:12202038, PubMed:12535518, PubMed:16168377, PubMed:16399501, PubMed:16606821, PubMed:32322062).  Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2 (PubMed:12202038, PubMed:16399501, PubMed:32322062).  Binds oxysterol, including 25-hydroxycholesterol, regulating interaction with SCAP and retention of the SCAP-SREBP complex in the endoplasmic reticulum (PubMed:32322062).  In presence of oxysterol, interacts with SCAP, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing SCAP from escorting SREBF1/SREBP1 and SREBF2/SREBP2 to the Golgi (PubMed:15899885, PubMed:32322062).  Sterol deprivation or phosphorylation by PCK1 reduce oxysterol-binding, disrupting the interaction between INSIG1 and SCAP, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBF1/SREBP1 and SREBF2/SREBP2 (PubMed:32322062).  Also regulates cholesterol synthesis by regulating degradation of HMGCR: initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligases AMFR/gp78 and/or RNF139 (PubMed:12535518, PubMed:16168377, PubMed:22143767).  Also regulates degradation of SOAT2/ACAT2 when the lipid levels are low: initiates the ubiquitin-mediated degradation of SOAT2/ACAT2 via recruitment of the ubiquitin ligases AMFR/gp78 (PubMed:28604676).
What are the official names of this protein?
Insulin-induced gene 1 protein, INSIG-1.
What is the protein family that this protein belongs to?
Belongs to the INSIG family.
Protein: OAT1_STAAR
Sequence: MNSIIELTDYYSSNNYAPLKLVITEGKGGKVWDTDGKQYIDCISGFSVANQGHCHPTIVKAMTEQASKLSIISRVLYSDNLGKWEEKICHLAKKDKVLPLNSGTEAVEAAIKIARKWGSDVKGITDGQVEIIAMNNNFHGRTLGSLSLSNHDAYKSGFHPLLQGTKTVDFGDIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILLIADEIQVGLGRTGKWFAMEWEQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIAISTAALDVLKDEQLVERSERLGSFLLKALLQLKHPSIKEIRGRGLFIGIELNTDAAPFVEQLIKRGILCKDTHRTIIRLSPPLVIDKEEINQIVAAFQDVFKN
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase 1, OAT 1, Ornithine--oxo-acid aminotransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2W01_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELAAVDEERHFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1o, U4-TRTX-Hhn1o, Hainantoxin-II-23, HNTX-II-23.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MNMA_TROW8
Sequence: MKVLAAMSGGVDSAVAAARAVDMGHDVVGVHLALSRSASGKRGCCTPRDAQDAAQAAQTIGIPFYVWDFSEEFQEKVIDNFISEYSAGRTPNPCLRCNEHIKFSSLLRRALALGFDAVCTGHYARVFLDEDGTYQLHRASSWAKDQSYVLAVLQQAQLKHCYFPLGATPSKKLVRQEADERGLKVSKKPDSHDVCFIPSSNTGAWLSQRIGRRDGDIIDDLGQRVGSHTGAFAYTVGQRKGLRLSSPAWDGKPRYVLDIEPISNTVVVGPRESLRVDELSGAFTTTGWCFTSRPIECSVQVRAHSDPVSAIAFIRDDVLVVRPDEPVFAVAKGQSAAIYRGTRVLGQLMIDNTKKYASS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIM_ACEAZ
Sequence: MNKKKNTILIGLYFLVGIMLFPDRIYAMHIAEGFLPVKWAGIWWIAMLPFLALGIKKVKSITQKEGPGIKMLLALAGAFVFVLSSLKLPSLTGSCSHPTGVGLGAILFGPWPMVVLGCIVLIFQAVLLAHGGLTTLGANVFSMAIVGPFVAYGAYRLLKKLNAPNWLSVFTGSALGNLLTYITTATQLAWAFPGKTGFIASLIKFMGVFATTQVPLAVTEGLVTVLIFNLLLEYSEGELKELSVISKGETV
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiM, Energy-coupling factor transporter probable substrate-capture protein CbiM, ECF transporter S component CbiM.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CPIA_ACIAD
Sequence: MIMKLVSDQIQERKFIIEFQLFNLIDELGLSVKKDHERKIFIYALLYVQLMHQPYSAMNTISQLEPVTTYEKIKISYYTNYLSTYLSTSYSQERERIISIISKTFIDSINPEMNLYNFNDFVTMFAFKKLLQQVFHEN
What is the function of this protein?
Acts as a PilB inhibitor to control natural transformation.  Inhibits type IV pili (T4P) extension by specifically binding and inhibiting the pilus extension ATPase PilB but not TfpB.  This activity probably modulates T4P extension under different environmental conditions.
What are the official names of this protein?
PilB-specific inhibitory protein CpiA, Competence pilus inhibition actuator.
Protein: NCAP_I80A4
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVDGKWMRELVLYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGIGTMVMELIRMIKRGINDRNFWRGENGRKTRSAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFSARSALILRGSVAHKSCLPACVYGPAVSSGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDNMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFEKSTVMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEDYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ACCD_ILLOL
Sequence: MEKWWFNSMLSNEELEHKCGLSKSADSLGPIGNASGSETPIINGIDKNIHSWSDNGSYSCSNVDHLFGVRDIWSFISDDTFLVRDSNGDSYSVYFDIENQIFEIHNDSYFLSELESAFSSYLNKRSFSSYLNSGPKSYNRNYDRYMYDTQYSWNNHINSCIDSYLHSEISIDSDIYSYICSESLSGSDSESSSIRTSINGSDFDINTKYGRLWVQCENCYGLNYQKFFRSKMNICERCGYYLKMSSSDRIELSIDPGTWDPMDEDMISMDPIEFHSEEEPYRDRIDFFQRTTGLTEAVQTGIGQLNGIPIAIGVMDFQFMGGSMGSVVGEKITRLIECATNRSLPVIIVCASGGARMQEGSLSLMQMAKISSALYNYQSNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLKKTIPEGSQAAEYLFHKGLFDLIVPRNPLKGVPSELFQLHGFFPLNQINKYK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: NU3C_SYNE7
Sequence: MAKWNSDCSLEFGVFVLNGYEYLLGFLLISSLVPILSLTASRLLRPGRRGPERRTTYESGMEPIGGAWIQFNVRYYMFALVFVIFDVETVFLYPWAVAFNRLGLLAFVEALIFITILVVGLAYAWRKGALEWS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3, NDH-1 subunit 3, NDH-C.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: HUTG_RHOJR
Sequence: MMENLLIPPPPWVGRVDGTSSHHLRWHQAVTPLHDGAEPGACVLIGFSSDEGVERNKGRRGAARGPDALRGALSSMALAEPLRVYDAGTVAVTDNRLEAGQMALGSVVAATLDAGQFPVVLGGGHEVAYGTYLGLAQAAVRTPKRRIGILNLDAHFDLRSDPVPSSGTPFRQILEQEHASGTALQYSVLGISQPSNTTALFDTARGYDVRYLLDDDCSVSDRHRVAVFVSEFLSDVDLVYLTIDLDVLPAAVAPGVSAPAAYGVPAETIQFVCDAVAASGKLAVCDVAELNPSFDIDNRTARTAARLIHRIVTKRIPIAV
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: AATC_CAEEL
Sequence: MSFFDGIPVAPPIEVFHKNKMYLDETAPVKVNLTIGAYRTEEGQPWVLPVVHETEVEIANDTSLNHEYLPVLGHEGFRKAATELVLGAESPAIKEERSFGVQCLSGTGALRAGAEFLASVCNMKTVYVSNPTWGNHKLVFKKAGFTTVADYTFWDYDNKRVHIEKFLSDLESAPEKSVIILHGCAHNPTGMDPTQEQWKLVAEVIKRKNLFTFFDIAYQGFASGDPAADAWAIRYFVDQGMEMVVSQSFAKNFGLYNERVGNLTVVVNNPAVIAGFQSQMSLVIRANWSNPPAHGARIVHKVLTTPARREQWNQSIQAMSSRIKQMRAALLRHLMDLGTPGTWDHIIQQIGMFSYTGLTSAQVDHLIANHKVFLLRDGRINICGLNTKNVEYVAKAIDETVRAVKSNI
What is the function of this protein?
Biosynthesis of L-glutamate from L-aspartate (PubMed:29649217).  Important regulator of levels of glutamate, the major excitatory neurotransmitter of the central nervous system (PubMed:29649217).
What are the official names of this protein?
Aspartate aminotransferase, cytoplasmic, Glutamate oxaloacetate transaminase 1.2, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA4_RHOOB
Sequence: MNTPAQKKITIVDTTLRDGMSSVSHQFTPQNVADIARGLDKAGVGTIEVAHGIGLGASSIQYGFAAATDPDYVRAAVDAVENADIAALYVPGIATLAELQKAIDAGIKTVRVAVHCTEADCGQQPVEWAKEQGLTVMTFLMMSHKLDPEPLAEQAAKLDSYGADVVYVVDSAGAMVPQHAGDRVAALRQVITADIGFHAHNNLGVGIANALTAAENGATFIDGSLRGLGASAGNAQTEVLAAAFERAGWDTGVDLFPLIDTAEHIVAPLMKEPQIVDETALILGYAGVYSTFFHPTKRAAKKFGVPARDILMELGRRGVIGGQEDMIIDVASELAGRTYETPALAGS
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 4, HOA 4, 4-hydroxy-2-keto-pentanoic acid aldolase 4, 4-hydroxy-2-oxopentanoate aldolase 4.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: ATP6_SHESH
Sequence: MAATGEALTPQGYIQHHLTNLSVGEGFWTWHIDSLLFSVGLGVLFLWLFRSVGKKATTGVPGKLQCFVEMIIEFVDSSVKETFHGRNPVIAPLALTIFVWVFMMNFMDMVPVDWIPSLAAAAGIPYMKVVPTTDLNITFSMAIGVFLLIIYYSIKVKGISGFVKELTMQPFNHWAMIPVNFLLETVTLIAKPISLALRLFGNLYAGELIFILIALMYGANMALSALGVTLQLGWLIFHILVITLQAFIFMMLTIVYLSMAHEDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UPPS_LEGPL
Sequence: MNHKLPQHIAVVMDGNGRWAESRGLPRVEGHKAGLDSVKKIINCCLEKKISCLSLFAFSSENWSRPVTEVNFLMELFLEALRKEIDDLNQHGIRLKFTGDREPLSQVLQKQMSDAEALTKNNQQLILNVVVNYGGKWDIVTAARKLIRTVLDGKLAYDEINEAVFAQFLDTKGMPEPDLFIRTSGELRISNFFLWQLAYTELYFTDVHWPDFNEHEFELALISFSKRARRFGQISQSE
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: GUAA_LIMRJ
Sequence: MANINLDAFDKIIALDFGSQYNQLITRRLRDFGIYSELLSHKLTADEIKEINPKGIIFSGGPNSVYDPNAFKVDPEIFKLGIPILGICYGMQLMSYDLGGKVEKADNSEYGRADIEVLDDEAVLLKGLPKKQYVWMSHGDLVTQAPAGFEVTATSKNCPIASIADNDRKFYGVQFHPEVRNSEYGLDILRRFAFDVCGAKANWTMDDFIDMQIDEIRKEVGDKKVILGLSGGVDSSVTAVLIHKAIGDQLTCIFVDHGLLRKNEADQVMDALSRDLGVNIIKVDAADRFLGKLEGVTDPEQKRKIIGKEFIEVFNEEAKKIKDADFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPKKLGFKLIEPLRKLFKDETRELGEKLGIPHELVWRQPFPGPGLGIRVIGEITPEKLEIVRESDAILREEIKKAGLDEEIWQYFTVLPGIRSVGVMGDGRTYDYAVAIRAVTSIDGMTADFAKIPWDILQKISVRIVNEVDHVNRILYDVTSKPPSTIEYE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: YQEB_ECOLI
Sequence: MNIFTEAAKLEEQNCPFAMAQIVDSRGSTPRHSAQMLVRADGSIVGTIGGGMVERKVIEESLQALQERKPRLFHGRMARNGADAVGSDCGGAMSVFISVHGMRPRLVLIGAGHVNRAIAQSAALLGFDIAVADIYRESLNPELFPPSTTLLHAESFGAAVEALDIRPDNFVLIATNNQDREALDKLIEQPIAWLGLLASRRKVQLFLRQLREKGVAEEHIARLHAPVGYNIGAETPQEIAISVLAEILQVKNNAPGGLMMKPSHPSGHQLVVIRGAGDIASGVALRLYHAGFKVIMLEVEKPTVIRCTVAFAQAVFDGEMTVEGVTARLATSSAEAMKLTERGFIPVMVDPACSLLDELKPLCVVDAILAKQNLGTRADMAPVTIALGPGFTAGKDCHAVIETNRGHWLGQVIYSGCAQENTGVPGNIMGHTTRRVIRAPAAGIMRSNVKLGDLVKEGDVIAWIGEHEIKAPLTGMVRGLLNDGLAVVGGFKIGDIDPRGETADFTSVSDKARAIGGGVLEALMMLMHQGVKATKEVLEVA
What are the official names of this protein?
Uncharacterized protein YqeB.
Protein: LIPA_TOLAT
Sequence: MTKPITVQPGVQLRDADKMALIPVKFLPEQEGEQLKKPDWMRIRLPKTDEKIQNVKNIMRKNNLHSVCEEASCPNLSECFNHGTATFMILGAICTRHCPFCDVAHGKPLAPDADEPKKLANTIREMALKYVVITSVDRDDLRDGGAQHFADCIREIRLASPNTRIETLTPDFRGRMDKALDVFRETPPDVFNHNLETAPRLYSMARPGADYAWSLKLLQKMKELHPDLPTKSGLMMGLGETNDEIVQVLKDLRAHGVTMLTLGQYLQPSRHHLPVKRYVPPQEFDELKAIALDLGFTHAACGPFVRSSYHADLQAQGQEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPP3_RAT
Sequence: MPVLSEDSGLHETLALLTSQLRPDSNHREEMGFLRDVFSEKSLGYLMKIHEKLRYYERQSPTPVLHSAMALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFEEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGITVLHKRPDEISQILAQSQGSITLKIIPATQEEDRFKESKVFMRALFHYDPREDRAIPCQEAGLPFQQRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKQFQERRLSYRRTTGTIPSPQNLRKPLYDQPCDKETCDCDGYFKGHYVAGLRRSFRLGCRERLTGSQEVKVPVGAESQVLLTYEEVARYQHQPGERSRLVVLIGSLGAHLHELKQRVVAEDPQHFGVAVPHTTRPRKSHEREGVEYHFVSKQAFEADIQHNKFLEHGEHKENLYGTSLEAIQTVMAKNKVCLVDVEPEALRHLRTPEFKPYVIFVKPAIQEKRKTPPVSPDSEDPATPLDEQQQEMAASAAFIDQHYGHLIDTVLVRQDLQSVCSQLRAVIESLSKDTYWVPISWVR
What is the function of this protein?
Participates in cell spreading through the phosphoinositide-3-kinase (PI3K) pathway by connecting CADM1 to DLG1 and the regulatory subunit of phosphoinositide-3-kinase (PI3K) (By similarity).  Stabilizes HTR2C at the plasma membrane and prevents its desensitization.  May participates in the maintenance of adherens junctions (By similarity).
What are the official names of this protein?
MAGUK p55 subfamily member 3, Discs large homolog 3, Protein MPP3.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.