PharMolix/UniProtQA huggingface dataset:
Protein: CYP3_USTMD
Sequence: MNTTKLLGTGALSPSFVFDHDSGNAIFGLSSSTLVVLVAMIAVSTLTLKSVLPGDRSINLPGPRGWPIVGSWFDLGNNWAEYFRQAAKEYGDVFKVHIGNRTVVVVNSPKAAHILFNEHGSSLISRPWFYTFHGVLSKSSAFTIGTSAWSDSTKNKRKAAATALNRPAVQSYMPIIVEESLDAVRRILNDGNAGKNGIVPYSYFQRLALNTSFQVNYGFRMGERDDGLFDEISEVIAKVASVRAVTGSLQDYVPLMRYLPANAKSKAAASYGLRRKKFMSKLYEELEQRVNQGKDESCITGNILKDTESRKKLSRLEIDSICLSMVSAGLDTFANTMIWTIGFLAKHPEIQRKAQAELLAHYPNRELPHVDSEDLVYIHAMAKEASRLFNVFRICLPRTNVSDVTYNNAVIPAGTTFFLNSWACNVDAEKFADPFEFKPERFMDKSASNAHVENKMGGVETYAFGMGRRMCPGVFLALREIYTTLVFLTHFFDIAPDGEYDIDPLTAVEDGRAFSVRPKPFKVRCTPRPGVDLSPVLDKQ
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of itaconic acid and 2-hydroxyparaconate (PubMed:26639528, PubMed:27750034).  Cis-aconitate is secreted by the mitochondrial tricarboxylate transporter MTT1.  In the cytosol cis-aconitate is converted into trans-aconitate via isomerization by the aconitate-delta-isomerase ADI1 (PubMed:26639528).  Decarboxylation of trans-aconitate by the trans-aconitate decarboxylase TAD1 then leads then to the production of itaconic acid (PubMed:26639528).  The cytochrome P450 monooxygenase CYP3 further converts itaconate to 2-hydroxyparaconate via oxidation of the double bond, leading to a transient epoxide, which can subsequently be lactonized to produce 2-hydroxyparaconate (PubMed:27750034).  Secretion of itaconate and possibly 2-hydroxyparaconate into the medium is mediated by the major facilitator ITP1 (PubMed:26639528, PubMed:27750034).  The glyoxalase domain-containing protein RDO1 is not involved in the biosynthesis of itaconate and 2-hydroxyparaconate, however, it might play a role in the further conversion of 2-hydroxyparaconate to itatartarate (PubMed:27750034).
What are the official names of this protein?
Cytochrome P450 monooxygenase CYP3, Itaconic acid/2-hydroxyparaconate biosynthesis cluster protein CYP3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ARGR1_STRP3
Sequence: MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
What is the function of this protein?
Regulates the transcription of the arc operon, involved in arginine catabolism.
What are the official names of this protein?
Arginine regulator.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CR015_HUMAN
Sequence: MQGQGALKESHIHLPTEQPEASLVLQGQLAESSALGPKGALRPQAQSPDVPVSWWQGSGKRLSHRLPHICSQPPLGPFLPLTWPSCGFFGLGGAASASLGLEVLQDSVSTWARGPCCPVHPQSLTVVCMCACMCVCVHVCACVYVCMCVLVCMCACACMRAHRYFLMDCAGICSPHGPGTQ
What are the official names of this protein?
Putative uncharacterized protein C18orf15.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MCTP2_ARATH
Sequence: MRNTTKLVVHVVDAQYLMPRDGQGSASPFVEVDFLNQLSKTRTVPKSLNPVWNQKLYFDYDQSVINQHNQHIEVSVYHERRPIPGRSFLGRVKISLCNIVYKDDQVYQRFTLEKKWLLSSVKGEIGLKFYISSSEEDQTFPLPSKPYTSPTQASASGTEEDTADSETEDSLKSFASAEEEDLADSVSECVEGKKSEEVKEPVQKLHRQEVFARPAPMQSIRLRSRENPHEAQKPMSRGANQLHPQNPNHLQSYGDTDLDDFKVKDMNLDLGERWPNPNAGERFTGTYDLVEQMFYLYVRVVKAKELPPGSITGGCDPYVEVKLGNYKGRTKIFDRKTTIPEWNQVFAFTKERIQSSVLEVFVKDKETLGRDDILGKVVFDLNEIPTRVPPNSPLAPQWYRLEDWRGEGKVVRGEIMLAVWMGTQADEAFPEAWHADSASVHGEGVFNIRSKVYVSPKLWYLRVNVIEAQDMIPSDRNRLPDVFVKASVGMQTLKTSICSIKTTNPLWKEDLVFVVAEPFEEQLVISVEDRVHTSKDEVIGKITLPMNVFEKRLDHRPVHSRWFNLDKYGTGVLEPDARRKEHKFSSRIHLRICLEGGYHVMDESTMYISDTRPTARQLWKQPVGMLEIGILGANGLVPMKLKDGRGSTNAYCVAKYGQKWVRTRTILDTLSPRWNEQYTWEVYDPCTVITLGVFDNSHLGSAQSGTADSRDARIGKVRIRLSTLEAHKIYTHSFPLLVLQPHGLKKTGDLQISVRFTTLSLANIIYNYGHPLLPKMHYLFPFTVNQVDGLRYQAMNIVSTRLGRAEPPLRKEVVEYMLDVDSHLWSMRRSKANFFRIMSLLSGYFLVGKWLEDVCNWRYPVTSVLVNVLFFILVMYPELILPTMFLYMFFIGLWNFRSRPRHPPHMDMKLSWAEAVGPDELDEEFDTFPTSRSQELVRLRYDRLRSVAGRIQTVVGDIAAQGERIQSLLSWRDPRATSLFILFCLAASVVLYAMPFKAIALASGLYYLRHPKFRSKLPSLPSNFFKRLPSSTDSLL
What is the function of this protein?
May function as a signaling molecule by regulating the trafficking of other regulators.
What are the official names of this protein?
Multiple C2 domain and transmembrane region protein 2.
What is the protein family that this protein belongs to?
Belongs to the MCTP family.
Protein: RECR_PSYA2
Sequence: MLTAKFDQLVKQLRILPGVGQKSAQRMALHLLTKKRPQGMALAQALDEAMRDIVECQRCHSFSDDAVCPLCQDPRRDDALLCVVETAADVMAIEQTAGYRGRYFVLGGHLSPIDGISADDLNIEQLVWRVKQEPVEELILATGTTVEGQTTAHFINEAVSRHVNKVTRLAQGVPMGGELEYLDSMTLGQAMQNRSFL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RL27_SALHS
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGEAVLAGSIIVRQRGTKFHAGTNVGCGRDHTLFAKADGKVKFEVKGPKNRKYISIVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GLPG_SALEP
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRGELARFIENPGDPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVMLACVLVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAGWFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRIS_ARCFU
Sequence: MLTKLFLKKKFEEYYSKNEVELPRKFKNREFAFVPLELLPDFVMHRHISFRSETDFRAYILSNVPAHIYFSSAYYERPAEDKMENKGWLGADLIFDIDADHLPVKAQSFEKALEMAKREIKKLTAVLRADFGIRDMKIYFSGGRGYHVHVHDEEFLSLGSAERREIVDYLRLNSPKIVVEDRFANSNAAKRVLNYLRKKLEEDERLTSKLKIKPADLKKEKLTKKVIRAVEKFDYSALSIYIDAPVTADVKRLIRLPGSLHGKTGLRVTEVEDIESFNPLKDALAFGDEAVVVKVARKLNLSIGDFSGKIYPGRVKLPEYAAVFLICRGDASYDS
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: ACEA_ECOLI
Sequence: MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECTLAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLAASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEAGFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARLAADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRGLAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIASFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKDGYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF
What is the function of this protein?
Involved in the metabolic adaptation in response to environmental changes.  Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
Protein: RUVA_CHLTE
Sequence: MFAFLRGELVTVSREEAVVEVSGIGYLLHISSGTSRRLPPEGSQVRLFTHHYVREDAQQLFGFLDEEELQLFRLLLTIGGVGPKLAMAVLSGLSVGEIQEAIVANRPETLYGITGVGKKTASRIILELRDKILKIQPAASGKTAGAPQALQLNEDALAALMTLGFPKPAAQKAISGILETSPGLSVEEVVRAALIAIHNNF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PHAC_METEX
Sequence: MGTERTNPAAPDFETIARNANQLAEVFRQSAAASLKPFEPAGQGALLPGANLQGASEIDEMTRTLTRVAETWLKDPEKALQAQTKLGQSFAALWASTLTRMQGAVTEPVVQPPPTDKRFAHADWSANPVFDLIKQSYLLLGRWAEEMVETAEGIDEHTRHKAEFYLRQLLSAYSPSNFVMTNPELLRQTLEEGGANLMRGMKMLQEDLEAGGGQLRVRQTDLSAFTFGKDVAVTPGEVIFRNDLMELIQYAPTTETVLKRPLLIVPPWINKFYILDLNPQKSLIGWMVSQGITVFVISWVNPDERHRDKDFESYMREGIETAIDMIGVATGETDVAAAGYCVGGTLLAVTLAYQAATGNRRIKSATFLTTQVDFTHAGDLKVFADEGQIKAIEERMAEHGYLEGARMANAFNMLRPNDLIWSYVVNNYVRGKAPAAFDLLYWNADATRMPAANHSFYLRNCYLNNTLAKGQMVLGNVRLDLKKVKVPVFNLATREDHIAPALSVFEGSAKFGGKVDYVLAGSGHIAGVVAPPGPKAKYGFRTGGPARGRFEDWVAAATEHPGSWWPYWYKWLEEQAPERVPARIPGTGALPSLAPAPGTYVRMKA
What are the official names of this protein?
Poly(3-hydroxyalkanoate) polymerase, PHA polymerase, PHA synthase, Polyhydroxyalkanoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the PHA/PHB synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_UREP2
Sequence: MAKKSLIAKQKKHQKFAVREYTRCVRCGRPHAVNRKFGVCRLCFRDLAYAGAIPGIKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: WNT4_SCEOC
Sequence: SGSCEVKTCWKAMPPFRKVGNVLKEKFDGATEVEQRKTGSTKVLVPKNSQFKPHTDEDLVYLDSSPDFCDHDLKNGVLGTSGRHCNKTSKAIDGCELMCCGRGFHTDEVEVVERCSCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors (Probable).  Plays an important role in embryonic development (By similarity).
What are the official names of this protein?
Protein Wnt-4.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CERK1_ORYSJ
Sequence: MEASTSLLVLVLAAAAFAAGTVTEAAGDGCSAGCDLALASFYVTPNQNVTNMADLFGIGAANYRSLAPYNPNIPNLDFINVGGRVNVYFTCGCRSLPGSPGATYLAGAFPFQMSRGQIYTSVAANYNNLTTAEWLQATNSYPANNIPDTAVINATVNCSCGDASISPDYGLFLTYPLRAEDTLASVAATYGLSSQLDVVRRYNPGMESATGSGIVYIPVKDPNGSYLPLKSPGKGASAGAIAGGVVAGVVVLAAIFLYIIFYRRRKAKQATLLQSSEDSTQLGTISMDKVTPSTIVGPSPVAGITVDKSVEFSYEELSNATQGFSIGNKIGQGGFGAVYYAELRGEKAAIKKMDMQATHEFLAELKVLTHVHHLNLVRLIGYCIESSLFLVYEFIENGNLSQHLRGMGYEPLSWAARIQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNYRAKVADFGLTKLTEVGGTSMPTGTRVVGTFGYMPPEYARYGDVSPKVDVYAFGVVLYELISAKEAIVRSTESSSDSKGLVYLFEEALNSPDPKEGLRTLIDPKLGEDYPIDSILKLTQLAKVCTQEDPKLRPSMRSVVVALMTLSSTSEFWDMNNLYENQGLVNLMSGR
What is the function of this protein?
Lysin motif (LysM) receptor kinase required as a cell surface receptor for chitin elicitor (chitooligosaccharides) signaling leading to innate immunity in response to biotic stresses.  Involved in the resistance to pathogenic fungi, probably by sensing microbe-associated molecular patterns (MAMP) and pathogen-associated molecular patterns (PAMP) (PubMed:21070404, PubMed:22891159, PubMed:24964058).  Involved in the detection of microbial peptidoglycans (PGNs) and mediates PGN response (PubMed:24964058).  Plays dual roles in PGN and chitin signaling during innate immunity.  Acts as an adapter for LYP4 and LYP6 and mediates signal transduction from the extracellular to intracellular spaces.  Participates in the activation of defense genes during response to PGN and chitin (PubMed:25335639).  Phosphorylates the downstream partner RLCK185 in response to chitin elicitation (PubMed:23498959).
What are the official names of this protein?
Chitin elicitor receptor kinase 1, OsCERK1, LysM domain receptor-like kinase 1, LysM RLK1, LysM-containing receptor-like kinase 1, LysM domain receptor-like kinase 9, OsLysM-RLK9.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SECA_SYNSC
Sequence: MLKLLLGDPNARKLKRYQPIVSDIQLLEEEIAPLSDDELRGRTAAFQERLANAGSLANQRPILDEILPEAFAVVREAGKRVLGMRHFDVQLIGGMVLHEGQIAEMKTGEGKTLVATLPSYLNALTGRGVHVVTVNDYLARRDAEWMGQVHRFLGLSVGLIQQDMRPEERRRNYNCDITYATNSELGFDYLRDNMAADISEVVQREFQYCVIDEVDSILIDEARTPLIISGQVERPQEKYQQAAEVANALARAAELSKDGIDPEGDYEVDEKQRSCTLTDEGFAKAEQMLGVADLFNPQDPWAHYITNALKAKELFVKDVNYIVRDGEAVIVDEFTGRVMPGRRWSDGQHQAIEAKEALAIQSETQTLASITYQNFFLLYPRLAGMTGTAKTEEVEFEKTYKLETTIVPTNRVRARQDWADQVYKTEAAKWRAVANETAEIHKNGRPVLVGTTSVEKSELLSSLLAEQEIPHNLLNAKPENVERESEIVAQAGRAGAVTIATNMAGRGTDIILGGNSDYMARLKLREVLLGRLVKPEEDHTPPVPLQRSAPGGFSDAAAPSLPRSGESLYPCPLTDDTDQALGQLARDLVKAWGDRALTVIELEERIATAAEKAPTEAPQIQALREAIARVKGEYDAVVKQEESRVREAGGLHVIGTERHESRRVDNQLRGRAGRQGDPGSTRFFLSLGDNLLRIFGGDRVAGLMNAFRVEEDMPIESGMLTRSLEGAQKKVETYYYDIRKQVFEYDEVMNNQRRAVYSERRRVLDGRALKKQVIGYGERTMGEIVEAYVNPDLPPEEWDLDQLVGKVKEFIYLLEDLTPDQVQGLGMEELKAFLQEQLRNAYDLKEGQIEQQRPGLMREAERFFILQQIDTLWREHLQAMDALRESVGLRGYGQKDPLIEYKNEGYDMFLEMMTNMRRNVIYSMFMFQPQAPKN
What is the function of this protein?
Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: FB107_ARATH
Sequence: MADWSLLPNDLLELIVGHLETSFEIVLFRSVCSSWRSVVPPQDQSRCLSIKTHDISFNAGFSFSGQPTDHPLFGSTLTKIPIYLVKFWTPFGDDYLLAEMREREGGEPMFLLSPLSSNRIIYGMGINKVLFNSLTSPIIPFGQYYEITYSEKQPIRYRYGLPCHLWDKLEWVEITERVEFLKLDSEDSRDFAVLFAGRMCNLVMYRSRNMSWTQVVEHPEKYAYQDLVAFKGKFYALDSSGRGRVFVVELSLEVMEIPSVRGSQQSSKENLVLSGEELLLVQRFTPEVRHYDEYLYTWFRVFRLDEEEGRESGFKLMTLTTE
What are the official names of this protein?
F-box protein At2g16300.
Protein: RECR_LACJO
Sequence: MQYPLPIARLIDNYMKLPGIGEKTATRLAFYTMDMPEQDVEDFSKSLMQVKENLHSCSICGNITESDPCEICRDSNRDRSTIMVVEQPKDVMAFEEMGEYNGLYHVLHGVLSPMDGVGPEEINIKSLITRLQKQDEVKEVILALNSSPEGEATAMYLAKLIKPAGLKVTRLAAGLAVGSDIEYANSITLKRAVQGRTDL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: S5A1_MACFA
Sequence: MATAVAEELLLAEERMLAALAYLQCAVGCAVLARNRETNLAYGRHASPSFRVRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMAIMFCTFNGYLQSRYLSHWAVYADDWVTDPRFLIGFGLWLAGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHRWYLQKFEEYPKFRKILIPFLF
What is the function of this protein?
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids.  It plays a central role in sexual differentiation and androgen physiology.
What are the official names of this protein?
3-oxo-5-alpha-steroid 4-dehydrogenase 1, SR type 1, Steroid 5-alpha-reductase 1, S5AR 1.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family.
What are the subcellular locations of this protein?
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TPM_HOMAM
Sequence: MDAIKKKMQAMKLEKDNAMDRADTLEQQNKEANIRAEKTEEEIRITHKKMQQVENELDQVQEQLSLANTKLEEKEKALQNAEGEVAALNRRIQLLEEDLERSEERLNTATTKLAEASQAADESERMRKVLENRSLSDEERMDALENQLKEARFLAEEADRKYDEVARKLAMVEADLERAEERAETGESKIVELEEELRVVGNNLKSLEVSEEKANQREEAYKEQIKTLANKLKAAEARAEFAERSVQKLQKEVDRLEDELVNEKEKYKSITDELDQTFSELSGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: LACR_STAAR
Sequence: MNKHERLDEIAKLVNKKGTIRTNEIVEGLNVSDMTVRRDLIELENKGILTKIHGGARSNSTFQYKEISHKEKHTRQIAEKRFIARKAASLIEDGDTLFFGPGTTVELLAEEVNHHTLTIITNCLPVYKILLEKQTAHFRVYLIGGEMRHITEAFVGEMANAMLEKLRFSKMFFSSNAVNKGAVMTSTLDEAYTQQLALSNSIEKYLLIDHTKVGKEDFTSFCQLNELTAVVMDYEDEEKVETIKTYIEVVD
What is the function of this protein?
Repressor of the lactose catabolism operon.  Galactose-6-phosphate is the inducer (By similarity).
What are the official names of this protein?
Lactose phosphotransferase system repressor.
Protein: YIDC_GRABC
Sequence: MDQKRLFLAIAISLGILLGFQGLYRHFVPEPPAAARTATNAGQGKPNNTLGAVPTDATASQSPPPKEGARLAVDAPRVKGSISLVGARFDDLVLRDYHETVDKNSPLVRLLAPLSGDEPYYVEYGWVPEESGIATPGRDTEWKADAATLTPNKPVTLSWDNGAGLTFMLKVAVDADYMFSVTQSVRNTTGKPVVLHPYARVRRDYRPEVEGYTVLHEGLIGVVDGILHEITYKSADSDGAKNNGLAFEHASTGGWAGITDKYWLTALIPDQITSVDFSFRDTKPNGRDGYQVGIISHNPDQVAAGAESASTTHLFAGAKVVSLLDHYQAEYHIPSFWEAVDFGWFWFITRPFFYALDWLYHLVGNFGVAILIFTVLVKAAFYPLASKSYRSMSKMRLLAPKIQSLRERYKDDPTRMQQEVMQLYKAEGANPASGCLPMLLQFPIFFSLYKVIFVTIEMRHAPFFGWIHDLSAVDPTNLFNLFGLLPFDPTHISPFLHLGIWPLIMGGTMYLQQKMNPPMPDPVQARMFQFMPIIFTFMLARFPVGLVIYWSWNNLLSIGQQWLIQRRTKLPRPELAKV
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS19_ALKEH
Sequence: MPRSVKKGPFVDGHLLSKVEKARESNSKRPIKTWSRRSMVLPQMVGLTIAIHNGRQHVPVLINENMVGHKLGEFAATRTYRGHAAGKKTK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: DAPA_CAMJJ
Sequence: MDKNIIIGAMTALITPFKNGKVDEQSYARLIKRQIENGIDAVVPVGTTGESATLTHEEHRTCIEIAVETCKGTKVKVLAGAGSNATHEAVGLAKFAKEHGADGILSVVPYYNKPTQQGLYEHYKAIAQSVDIPVLLYNVPGRTGCEISTDTIIKLFRDCENIYGVKEASGNIDKCVDLLAHEPRMMLISGEDAINYPILSNGGKGVISVTSNLLPDMISALTHFALDENYKEAKKINDELYNINKILFCESNPIPIKTAMYLAGLIESLEFRLPLCSPSKENFAKIEEVMKKYKIKGF
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_ANAMM
Sequence: MKVGVEAIRELRQITGAGLGDCKEALETCSGDMEKAKVYLREKGLSKAYKKSHRDAADGLVAVRVEGDKGAILKLGSETDFVARNEKFRSLAAELVSSLLKHGAEDLSSFSASPYDGGSGVSVADEVVNAAAVLGEHVVLSGIGFLELGGPGVIGSYIHGAVGEGIGRAGALVALEATTAKTEALLEFARQLAMHIVAAKPESVSVETLSNDLVEREREIVAKQVEALGKPESVASKIVDGRMQKFFEDMVLLEQTFIMDGSTKIRDLLHNKGQDLGCEVRIVAYRLFSVG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_THEKO
Sequence: MPKGCLVITVSGLAGSGTTTLCRNLAKHYGFKHIYAGLIFRQMAKEMGMTLEEFQKYVELHPEIDREIDRRQIEAAKECNVVIEGRLAGWMVKNADLKIWLDAPIMERAKRVAKREGISVEEAFVKIAEREKQNRKRYLNLYGIDIEDKSIYDLIINTAHWGPDGVFAIVKAAIDHLSPSGDAGEDEKEKEVG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOTB_HELAH
Sequence: MMITKQSYKKLALMRVFVFSLSAFIFNTTEFVPIALLSDIAKSFEMESASVGLMITLYAWIVSLGSLPLMLLSAKIERKRLLLFLFGLFIVSHILSVVAWDFWVLLISRMGIALAHSVFWSITASLVIRVAPIGRKQQALGLLALGSSLAMILGLPLGRIIGQMLDWRSTFGMIGGVALLVALLMYRLLPSLPSRNAGTLSSLPVLMKRPLLVGIYLLVILAISGHFTTYSYIEPFIIQISQFSPEVATLMLFVFGLAGVMGSFLFGRFYEKNPKKFIACAIILVLCPQLLLFSFKHLEWVIFLQIFLWGIGITSLGISLQMRVLQLAPNATDVASAIFSGSYNVGIGSGALFGSIVIHQLGLGYIGFVGGALGLLALFWFNFITIKFGAK
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRH_COREF
Sequence: MTTSSIEPRNSYKRVMLKLGGEMFGGGKVGIDPDVVDNVARQIAEVAKSGAEIAVVIGGGNFFRGAELQQRGMDRARSDYMGMLGTVMNCLALQDFLGQHGVECRVQTAINMAQVAEPYLPLRAERHLEKGRVVIFGAGMGMPYFSTDTTAAQRALEIGCDVLLMAKAVDGVYSADPRTNPDAELFTEITPKEVIEKSLKVADATAFSLCMDNNMPILVFNLLTDGNIARAVNGERIGTLVQS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.