PharMolix/UniProtQA huggingface dataset:
Protein: AL2CL_BOVIN
Sequence: MCSPEEAALLRLEEVFSATLARINSLVFQPLLEAGPEASDPWGRECLQLLQQLHSSSQQLWDVMEESLHSLRERLRRPEAVGLESLLLLQSADRVLQVHLEYIESYTCCVAVQAFQKAVKRRSEYWRGQRKALRQVLSGLSSEGSVGTALLQALRQPLAHHVQQYVLLLLSLGDTVGECHPTRELVIHAASLFGDLQSFMRQELDQATATQALWPTLSSRLRDVLCTPARRLLQDSQDVPVTVTPLRAERVLLFDDALVLLQGHNIHTFDLKLVWVEPGQDRCTFHLLTPEEGFSFCSKDPQGLVVWQWKVTQAVCQALRGKKDFPVLGAGLEPSEPPTCRCGAYTFHAEGRFCQATYEGEWYWGRPHGKGTLKWPDGRNHVGDFCQGLEHGFGIRLVPQASEDKFDCYKCHWWEGSMCGYGICEYSTSEVYKGYFQEGLRHGFGVLESAPQAPRPLRYTGHWERGQRSGYGVEEDSDRGERYIGMWQADQRHGPGVMVTQAGVCYQGTFQADKMVGPGILLSDDDSLYEGTFTRDLTLVGKGKVTFPNGFTLEGSFGSVSGRGLHTQGVLDTAALPPDPSSTCKRQLGQGVFPVESRWQGVYGAFRDFVRAGCPGDLREALLGFHVQSSRELRKSQEYLCCERTCPEDQAGRMEDLLEELLQHREPEALQQCLRKALSNSLHPLGKLLRTLMLTFQATYAGIGANKHLQGLAQEEVKQHAQELWAAYRGLLQVALQRKGQAPEEDEDAETRDLRVHSLVLPLVLPSFYSELFTLYLLLHEREDSLYSQGITHLSLFPDARLLEFLDVQKHLWPLKDLTLTTNQRYSLVRDKCFLSATECLQKMITTVDPREKLEVLERTYGEIEATVSRVLGREHKLPMDDLLPLLIYVVSRAQIQHLGAEIHLIRDMMDPLHTGGLYDFLLTALESCYEHIQKEDMRLHRLPSRWSSREPW
What is the function of this protein?
Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase.  Regulates the ALS2-mediated endosome dynamics (By similarity).
What are the official names of this protein?
ALS2 C-terminal-like protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells (By similarity).
Protein: YFGH_ECOLI
Sequence: MMKFKKCLLPVAMLASFTLAGCQSNADDHAADVYQTDQLNTKQETKTVNIISILPAKVAVDNSQNKRNAQAFGALIGAVAGGVIGHNVGSGSNSGTTAGAVGGGAVGAAAGSMVNDKTLVEGVSLTYKEGTKVYTSTQVGKECQFTTGLAVVITTTYNETRIQPNTKCPEKS
What are the official names of this protein?
Uncharacterized lipoprotein YfgH.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TXD17_PONAB
Sequence: MARYEEVSVSGFEEFHRAVEQHNGKTIFAYFTGSKDAGGKSWCPDCVQAEPVVREGLKHISEGCVFIYCQVGEKPYWKDPNNDFRKNLKVTAVPTLIKYGTPQKLVESECLQANLVEMLFSED
What is the function of this protein?
Disulfide reductase.  May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.  Modulates TNF-alpha signaling and NF-kappa-B activation.  Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide (By similarity).
What are the official names of this protein?
Thioredoxin domain-containing protein 17, Thioredoxin-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_LACH4
Sequence: MTKGILGRKVGMTQIFTKDGVLVPVTVVEATPNVVMQVKTVESDGYEAVQLGYQDKREVLSNKPEKGHADKAKTSPKRFIREIRGVELKDYEVGSEVTVDTFKEGDVVNVTGTSRGHGYQGNIKRWGQSRGPETHGSRYHRIPGSMGSIINRVPKGKRLPGHMGMKKVTIENLVIEKVVADKNVLMIKGNVPGAKNSLIVVKTASKAVKADK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL7_LACAC
Sequence: MALDTEKIIEELKGASILELNDLVKAIEDEFDVTAAAPVAAAGAAGAAEAKSSFDVELTEAGQEKVKVIKVVRDITGLGLKDSKDLVDGAPKNVKEGVSEDEANDIKAKLEEVGATVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: HPCB_ECOLX
Sequence: MGKLALAAKITHVPSMYLSELPGKNHGCRQGAIDGHKEISKRCREMGVDTIIVFDTHWLVNSAYHINCADHFEGVYTSNELPHFIRDMTYNYEGNPELGQLIADEALKLGVRAKAHNIPSLKLEYGSVVPMRYMNEDKRFKVVSISAFCTVHDFADSRKLGERIVKAIEQYDGTVAVLASGSLSHRFIDDQRAEEGMNSYTREFDRQMDERVVKLWREGQFKEFCNMLPEYADYCYGEGNMHDTVMLLGMLGWDKYDGKVWSLSPSYSQASWHRSG
What is the function of this protein?
Transforms homoprotocatechuic acid (HPC) into 5-carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS).
What are the official names of this protein?
3,4-dihydroxyphenylacetate 2,3-dioxygenase, Homoprotocatechuate 2,3-dioxygenase, HPC dioxygenase.
Protein: FPG_NOCSJ
Sequence: MPELPEVEVVRAGLERHVLGATIARVDVLHPRPVRRDLRGPAGFAAALTGRRIEAARRRGKYLWLPLDNGDALLGHLGMSGQLLVQPPDAPDERHLRVRLALEGADEGRELRFVDQRMFGGLSVSAGGADLPPEIAHIARDPLDPEFDDDDFVRRVRRRTSGVKRQLLDQNLISGVGNIYADEALWRARIHGERPGDRLTATRVRELLAHAREVMLAALGEGGTSFDALYVNVNGESGYFDRSLHAYGREGEACERCGTPIRRVAFMNRSSYFCPVCQPAPRRRRAASSRVRVPD
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: MTRA_MYCTO
Sequence: MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
What is the function of this protein?
Member of the two-component regulatory system MtrA/MtrB.
What are the official names of this protein?
DNA-binding response regulator MtrA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_BORPD
Sequence: MSFVALIPARMASTRLPDKPLADIAGKPMVVRVAERAARSGATGVYIATDDARVAQAAAAHGHAALLTRADHPTGTDRLAEAVEQLGLADDTVVVNVQGDEPLIDPALVDAVAATLQASPDAAIATCACPLADAEALFNPNVVKVVCGAGGRALYFSRAPIPWARDALAGGTRVLAPGLPALHHIGLYAYRAGFLRRFPALPQGALEHYEALEQLRALEHGHAIVVHRTPQPPMAGVDTPADLERVRALYADGL
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPE_ECO81
Sequence: MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAAQAFHLTNDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPAEVAYGA
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRU_AGADC
Sequence: MSFMKKSLLLVLFLGVVSLSNCEEEKGENENEDHEEHHEEKRLLGDLLGQTSKLVNDLTDTVGSIV
What is the function of this protein?
Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria.  Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).
What are the official names of this protein?
Dermaseptin PD-3-7.
What are the subcellular locations of this protein?
Secreted.
Protein: SYDND_PARP8
Sequence: MSMRSEYCGLVTEHLLGQTVSLCGWVSRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFKTAEGVRNEFCVQVKGVVRNRPEGTTNAGLKSGKIEVLCHELNVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAMEVRKYLDSRGFIDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETSFLSEQEIRDLFEDMTRHVFKETIGVELDAKFAVMPYSEAMSRFGSDKPDLRVKLEFTELTDAMKDVDFKVFSTPANTKDGRVAALRVPKGGELSRGDIDSYTEFVRIYGAKGLAWIKINEVAKGRDGLQSPIVKNLHDAAIAAIIERTGAQDGDIIFFAADRAKVVNDSLGALRLKIGHSEFGKANGLVEAGWKPLWVVDFPMFEYDEEENRYVAAHHPFTSPKDEHLEYLETDPGRCLAKAYDIVLNGWEIGGGSVRIFQEDVQSKVFRALKIGAEEARLKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDVIAFPKTQRAQDLLTQAPSEVDERQLRELHIRLRQPEQKA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALBA2_AERPE
Sequence: MACEGAPEVRIGRKPVMNYVLAILTTLMEQGTNQVVVKARGRNINRAVDAVEIVRKRFAKNIEIKDIKIDSQEIEVQTPEGQTRTRRVSSIEICLEKAGESA
What is the function of this protein?
Binds double-stranded DNA tightly but without sequence specificity.  It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture.  However, it does not significantly compact DNA.  Binds rRNA and mRNA in vivo.  May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).
What are the official names of this protein?
DNA/RNA-binding protein Alba 2.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: HIS8_METMA
Sequence: MLMSLSRRELIKKEIFDIEEYVPGRSIEEIASTYGLKPESIIKLGSNENPLGPSPKAVKALIEAAPGANIYPSADAHELREALSKYTGFPVSNIVASGPGMDGLLDGLCRIIIEKGDEVIVPIPTFSYYELPARACGAEPVFIRRNQDFSLNPEKILEAVSPRTKIIFLCSPNNPSGNLLPEADLRKIIENTDALVFVDEAYVEFADRNLAALVNEYDNVAVGRTFSKVFGLAGLRLGYGIMPEWLTKEYLRAATPFSVSLPALRAGLAALSDTEYLNKSINLAREGREYLKEKIPFKVYPSQANFVLVDVSPLKAKKVTESLLKKGIIVRPCDSFREAGDSFIRVTVGTPEQNEKVVRAFEISKSEV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RK11_GUITH
Sequence: MAKKVVAIIKLALEAGKATPAPPVGPALGQRGVNIVMFCKDYNARTADKAGLIIPVEITVYEDKSYTFVLKTPPASVLLAKAAGVQKGSGNPKKTQVGSVTKKQVEEIAQTKLPDLNTRRLESAIRIIEGTAKNMGIGVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LACB_STRPN
Sequence: MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPIFGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNANVIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: VN1R2_HUMAN
Sequence: MTHTLYPTPFALYPINISAAWHLGPLPVSCFVSNKYQCSLAFGATTGLRVLVVVVPQTQLSFLSSLCLVSLFLHSLVSAHGEKPTKPVGLDPTLFQVVVGILGNFSLLYYYMFLYFRGYKPRSTDLILRHLTVADSLVILSKRIPETMATFGLKHFDNYFGCKFLLYAHRVGRGVSIGSTCLLSVFQVITINPRNSRWAEMKVKAPTYIGLSNILCWAFHMLVNAIFPIYTTGKWSNNNITKKGDLGYCSAPLSDEVTKSVYAALTSFHDVLCLGLMLWASSSIVLVLYRHKQQVQHICRNNLYPNSSPGNRAIQSILALVSTFALCYALSFITYVYLALFDNSSWWLVNTAALIIACFPTISPFVLMCRDPSRSRLCSICCRRNRRFFHDFRKM
What is the function of this protein?
Putative pheromone receptor.
What are the official names of this protein?
Vomeronasal type-1 receptor 2, G-protein coupled receptor GPCR25, hGPCR25, V1r-like receptor 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSRA1_PSEPH
Sequence: MLILTRKVGESINIGDDITITILGVSGQQVRIGINAPKDVAVHREEIYQRIQAGLTAPDKRETP
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability (PubMed:17704818, PubMed:23635605).  Post-transcriptionally represses the expression of genes controlled by GacA/GacS (PubMed:15601712, PubMed:23635605).  Binds the 5' UTR of mRNA; the mRNA binds to the outside edge to each monomer and each dimer could bind the same mRNA twice (PubMed:17704818).  Recognizes a (A/U)CANGGANG(U/A) consensus, binds to GGA (part of the Shine-Dalgarno sequence) in the 5' UTR loop, which prevents ribosome binding (PubMed:17704818, PubMed:24561806, PubMed:23635605).  Overexpression represses target protein expression; mutating nucleotides in the 5' UTR abolishes repression in vivo (PubMed:17704818, PubMed:23635605).  Binds specifically to small RNAs (sRNA) RsmX, RsmZ and RsmY; these sRNAs fold into secondary structures with multiple GGA sequences in loops to which the CsrA proteins bind (PubMed:15601712, PubMed:16286659, PubMed:24828038).  Binding to RsmX, RsmY or RsmZ titrates the protein so that it can no longer bind mRNA and repress translation (PubMed:15601712, PubMed:24828038).  RsmZ can bind up to 5 CsrA1 (rsmE) dimers; they bind cooperatively to GGA sequences in RsmZ in a defined order (PubMed:24828038, PubMed:24561806).  Required for optimal expression and stability of sRNAs RsmX, RsmY and RsmZ (PubMed:15601712, PubMed:16286659).  Four CsrA1 dimers maximally protect RsmZ from RNase activity (PubMed:24828038).  Deletion of rsmX, rsmY or rsmZ alone has no detectable phenotype, but a double rsmY-rsmZ deletion has a marked decrease in production of secondary metabolites HCN, exoprotease AprA, antifungal agent 2,4-diacetylphloroglucinol and swarming motility, and protects cucumber plants from fungal infection less well than wild-type; the triple sRNA deletion has even stronger loss of these phenotypes (PubMed:16286659).
What are the official names of this protein?
Translational regulator CsrA1, Carbon storage regulator 1, Regulator of secondary metabolites RsmE.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_JANSC
Sequence: MQVSVRDNNVDQALRALKKKLQREGVFREMKLKQHYEKPSEKRAREKAEAIRRARKLARKKLQREGML
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: TRUB_VEREI
Sequence: MPPASRTRVQRRPVHGVLLLDKPLALSSNQALQKAKWLLRAEKAGHTGTLDPLATGVLPLCFGAATKFSQLQLDAPKTYEAIALPGVTTSTGDAEGAVLQRCAVDPAQLAPERLSAVQRQFTGPISQLPPMHSALKKDGRALYTYARAGIALERAARAVVIHALELSLVQHAPAQTAIKIAVTCSKGCYIRTLAEDIGAALGCGAHLSALRRTDSGGIGIERCISLERLQALPEAERLACLQPPQSLLTRHLRVTLDSDNAARFLSGLPRRGAWPDAPAVAVFGADPPALLGVGHIAGGCLLPDRLLSALEIAQILASQPQRQDCGILEET
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RL15_STRU0
Sequence: MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKSRSGGGVRLGFEGGQTPLFRRMPKRGFSNINTKEYALVNLDQLNVFEDGTEVTPVVLKEAGIVRAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: GSA_DESAL
Sequence: MEKSKELFARACKTIPGGVNSPVRACGSVGTDPCFIARGQGSAIFDADGKQYIDYIGSWGPLILGHRHPAVIKAIEAALANGCTFGAPTELEIDLAEAVVNIMPSVEMVRMVNSGTEATMSAIRLARGATGRDGIVKFDGCYHGHGDSLLVAAGSGVATLGIPGSPGVPDKVAESTASLEYNNIEAVKEYCKKKGDRTAAIIVEPVAGNMGVVAPKPEFIQGLREVCDQYGIVLILDEVMTGFRVALGGAQSLYGVTPDLTTMGKVIGGGLPVGAYGGKRSLMEKIAPSGPVYQAGTLSGNPMAMAAGIATLKEISAPGFYEALEKSSQTLADGLKKAAADAGVEAVISRVGSMQTLFFSAGPVENFEDAKKCDLDRFSKFYQGMRAEGVFLPPSQFEAWFVSSAHTEADIEATLKAAEKVLRQL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V007_FOWPN
Sequence: MLYSVFTRIYKIRKNNKTEMILAIYDRNAYIVKKTGIGSILLRDNGTRNTMLNIIYDTSSRNMQMVLRVSVL
What are the official names of this protein?
Uncharacterized protein FPV007/FPV254.
Protein: PSAB_EMIHU
Sequence: MATKFPKFSQALAQDPATRRIWYGIATAHDLESHDGMTEENLYQKIFASHFGHLAIIFLWTSGNLFHVAWQGNFQQWVLNPLKVKPIAHAIWDPHFGQSAIKAFTRGGVSYPVNIATSGVYHWWYTVGMRTNEDLYFGALGLLVLSTTLLFAGWLHLQPKFRPGIAWFKNNESRLNHHLSGLFGVSSLAWSGHLIHVAIPESRGQHIRWNNFTSTLPHPEGLTPFFTGNWGLYAENPDTAQHIFGTSEGAGTAILTFLGGFHPQTQSMWLTDIAHHHLAIAVVFIFAGHMYRTNWGIGHSMKEILDAHVPPKGRLGAGHRGLFETITDSLHMQLGLALASLGVATSLVAQHMYALPSYAFMAKDYVTQAALYTHHQYIAGFLMVGAFAHGAIFFVRDYDPEVNKDNVLARMLQHKEAIISHLSWVSLFLGFHTLGLYIHNDVCVAFGTPEKQILFEPVFAQFIQAASGKALYGFDVLLSSSTSAASVASSKIWLPGWMEAINSGKNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAMFWMLNTISWVTFYWHWKHLTVWGGNAAAFNESSTYIMGWLRDYLWLNSSPLINGYNAFGMNAQAVWAWMFLFGHLIWATGFMFLISWRGYWQELIETLVWAHERTPIANLVKWRDKPVALSIVQARLVGLAHFTVGFIFTFAPFVIASTTGKFA
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: YCXC_BACSU
Sequence: MVKHQQTPAYIAAILYSFIIGLSFLFVKIALQTAEPFDILAHRFTIAFAAATVPILFGWVKLSIRVKDVIDILPLALLYPALFFSFQAFGLVYSSSSEAGIIQAAIPIFTMVFAAYVLKERPTWTQKGFTVLSVAGVMFIFVMKGVDVESASLKGSLLILLSALSSAMYNTAARKMTQRFKLTELTYIMSAIGFVVFNAIALVRHGAAGTVGTYFLPFREPGFVLAIVYLGVLSSLVTSFLSNYTLSRIEAFKMSAFNHVSTIVTMIAGFVILNESLAWYHLAGAVCIMIGVVGSNINLEKKTKRPGMPAKK
What are the official names of this protein?
Uncharacterized transporter YcxC.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS1_PYRCJ
Sequence: MLLAIPSKGRLLDPTLKLLEAIGMRLLASDERALVVPTSWRDVNVIRARPEDIPYIVESGKVWAGVTGHDYVVESGASVVEALELGFGRGRLVVAVPKSSGIKTVDELPPGTRVATKFVNIAYNYFAELGKRVRVVRVTGSVEILPQLGIADAILDVMATGTTLEVHGLVPIATVLETSARLIVHPSYVNHELTKKLTTFIQGYYAAQGKKMIFLNVPASRLEKVLAVLPAMEAPSVTPLAKGDVYEVFSVVPEDELPDIVIRLKEAGAKDIVVTPIEKLIS
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_XANAC
Sequence: MTAVLPLPQPLADPAPRDPRQRLQREQLRLGKRLQRQVGQAIADFGMIAPGDKIMVCLSGGKDSYTLLDMLLQLQRKAPVPFSLVAVNLDQKQPDFPAHVLPAYLRGLGVPFAIVEQDTYSVVSRVIPAGKTMCSLCSRLRRGALYAYAQTHGVTKIALGHHRDDIVATFFMNLFHHARLAAMAPKLRSDDGAHVVIRPLAYVREADIAAYAQARQFPIIPCNLCGSQENLQRQQVGKLLQQWDRESPGRVEQIARALGDVRPEQLADRTLFDFLALGRSGDAPSGLDPDPRAWLSAGHATHDSD
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGLA_DANRE
Sequence: MGRSRSRSSSRSKHSKHSRKRSRSKSKSKKRSRSKEPKRNRRSRSRSGSRRDRGGSPPDRTDMFGRTLSKRNNDEKQKREEEDRRVEIERQRKIRQQEIEERLIEEETARRVEELVARRVEEELEKRRDEIEHEVLRRVEEAKRIMEAQLLQELERQRQAELNAQKAREEEEKSKRVELERILEENNRKIADAQAKLAEDQLRIVEEQRKIHEERMKLEQERQKQQKEEQKMILGKGKSRPRLSFSLKATE
What are the official names of this protein?
Arginine and glutamate-rich protein 1-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0430 family.
Protein: AZOR_CALS8
Sequence: MAKLLYIKANPKSDQSSRTFIISEHFIKVYKEFHPNDQIITLDLYKEGIHFLSQEDINDIFAPKTEASKHHPILKYAYQFLEADKYVFAAPMWNLGIPAILKAYIDYITVSGITFKYTEQGAVGLLRGKKAVHIMATGGEYKTPPFSDFEMANRYLKTILGFMGVEDFQTITAQRLDIVGEDVEKIISNALKEAEEIAKRF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: PANC_THESQ
Sequence: MKIIETIEEMKKFSEEMREKKKTIGFVPTMGYLHEGHLSLVRRARDENDVVVVSIFVNPTQFGPNEDYERYPRDFERDRKLLEKENVDCIFHPSVEEMYPPDFSTYVEETKLSKNLCGRSRPGHFRGVCTVVTKLFNIVKPHRAYFGQKDAQQFRVLRRMVRDLNMDVEMIECPIVREPDGLAMSSRNVYLSPEERQQALSLYQSLKIAENLYLNGERDAEKIKEEMIKHLSRFDKVKIDYVEIVDEETLEPVEKIDRKVIVAVAAWVGNARLIDNTILG
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KR251_HUMAN
Sequence: MHNRSQGFFFSSCHPQNHVSYGCQSPSFIFCRCQSLNFVSRTCYPLSYFSYGNQTIGSISNSFRSLNYVSHSFQPISFMHSSFQPACSDFVGWQSPFLRRTC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity).
What are the official names of this protein?
Keratin-associated protein 25-1.
What is the protein family that this protein belongs to?
Belongs to the PMG family.