PharMolix/UniProtQA huggingface dataset:
Protein: GPR27_RAT
Sequence: MANASEPGGGGGGAEAAALGLRLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGTPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGADDEDAPCALEQRPDGAPGALGFLLLLAAVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAITLLFLLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPQATQATLPCDLKGIGL
What is the function of this protein?
Orphan receptor.  Possible candidate for amine-like G-protein coupled receptor (By similarity).
What are the official names of this protein?
Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS6_ECOLU
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETTDDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PDXS_BACC1
Sequence: MTNVTGTERVKRGMAEMQKGGVIMDVINAEQAKIAEEAGAVAVMALERVPADIRAAGGVSRMADPTIVEEVMGAVSIPVMAKCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKRDYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVEAVRHMRQVNAEIRQVASLREDELMTYAKNTGAPYEVLLEIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSENPAKFARAIVEATTHYEDYELIASLSKGLGNAMKGIEISTLLPEQRMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: YQ15_CAEEL
Sequence: MEHFHGNRWDQLRAVEADILCPPPADPFQIFPSGWTRASELSEKGWRELLDRRRSQSPPPREPSPDVRRAIRRTPPPRVNRVAPIRLPERRPLRQLNANDARRPAQDAANRINQENMRAGNIDNGQPRRRALSPTQLPGVRAIPKDFNRFFRGLLTPGEFFAKSQTRYLGPFDEMPTEDTLPAADEYIILQRMGRLPDSGKSIFRQVGNLST
What are the official names of this protein?
Uncharacterized protein C05C10.5.
Protein: FZD7_MOUSE
Sequence: MRGPGTAASHSPLGLCALVLALLGALPTDTRAQPYHGEKGISVPDHGFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGAGGSPTAYPTAPYLPDPPFTAMSPSDGRGRLSFPFSCPRQLKVPPYLGYRFLGERDCGAPCEPGRANGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCPPGHFSPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRLSHSSKGETAV
What is the function of this protein?
Receptor for Wnt proteins.  Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  Activation by WNT8 induces expression of beta-catenin target genes.  Following ligand activation, binds to CCDC88C/DAPLE which displaces DVL1 from FZD7 and leads to inhibition of canonical Wnt signaling, activation of G-proteins by CCDC88C and triggering of non-canonical Wnt responses (By similarity).  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
What are the official names of this protein?
Frizzled-7, Fz-7, mFz7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Associated to the plasma membrane in the presence of FZD7 and phosphatidylinositol 4,5-bisphosphate (PIP2). Localized in recycling endosomes in other conditions.
Protein: VGA1_ALHV1
Sequence: MRLHFLFYRSIEFMYYKKSRHKIFCITLSLYFLTAHKRPSARNPITDFFSRIWGPCFYKWSRHQLLLVNQLMLSPCRNKCSLTSADQCITANEDTTK
What are the official names of this protein?
Uncharacterized gene A1 protein.
Protein: HSLU_JANSC
Sequence: MSDLTPREIVSELDRFIIGQSDAKRAVAVALRNRWRRKQLGDDLRDEVYPKNILMIGPTGVGKTEISRRLAKLAKAPFIKVEATKFTEVGYVGRDVEQIIRDLVDAAQVMIRENMREEVKAKAHDAAEERVIEALAGKDAREQTRDMFRKKLRAGELDDTVIELEVADNSNPLGGFEIPSQPGGMGGMGPGMMNLGDLFKGMGGRTVKRRLTVAASYDLLIEDEADKLLDAETVTKEALSAVEQSGIVFIDEIDKVCAKSDARGADVSREGVQRDLLPLIEGTTVSTKHGPVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVNLRALTEDDFVRILTETDNALTRQYTALMATEEVAVEFTDGGIRALAHIAAEVNESVENIGARRLYTVLERVFEELSFTAPDRSGDAVTVDEAFVEQNLGELTRSTDLSRYVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXA5_ANDAU
Sequence: MMKLMLFSIIVILFSLIGSIHGADVPGNYPLDSSDDTYLCAPLGENPFCIKICRKHGVKYGLMLRLPCWCEYFGKIKNVKI
What is the function of this protein?
Probable neurotoxin that inhibits ion channels.
What are the official names of this protein?
Toxin-like peptide AaF1CA5.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH101_VIBVU
Sequence: MNIRPLHDRVIVERQEVESKSAGGIVLTGSAAEKSTRGVVLAVGKGRILENGTVQPLDVKVGDTVIFAESYGTKTEKIDGKEVLIMSENDIMAIVD
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES 1, 10 kDa chaperonin 1, Chaperonin-10 1, Cpn10 1.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_ALCBS
Sequence: MNGDLNRLMARLGYQFQDLSLLELALTHRSVSRHRNYERLEFLGDAQLGQIISVALFEQFPEAAEGQLTRMRASLVRGQTLALVARELGLGEYLVLGGGELKSGGFRRDSILADALESIIGAMLLDGGEPRCREVVLAWFAPRLDAISPQSAQKDAKTRLQEWLQARKFELPTYEVTQVEGLAPKQTFDVQCSLDNVQQIFIAQGASRRKAEQEAASLALEWLEQQYD
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_SALPA
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHQDFDALNILRPDSEPRATHHIQEIIELTRTLIEKGHAYVADNGDVMFDVPTDPTYGQLSRQDLEQLQAGARVDVVDVKRNPMDFVLWKMSKEGEPSWPSPWGEGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGEYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLYTALRGTDKSAAPAGGEAFEARFVEAMNDDFNTPEAYSVLFDMAREVNRLKGEDMTAANAMASHLRKISGVLGLLEQEPDVFLQSGAQADDGEVAEIEALIQQRLDARKAKDWAAADAARDRLTEMGIILEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYG_MESFL
Sequence: MEKLIAHLKSQGFIFQGSEIYGGLANSWDYGPLGVEVKNKLKQAWWNHFVRKNPYNIGLDSSIILNSSVWKASGHIDGFNDPLIDCKKCNSRWRADKLIEEFNSEINAGVMTENQMEEFIREQNIKCPKCQACDFTQIRKFALMFKTNQGVLEDESSSVYLRPETAQGIFINFKNAQRSLRKKLPFGIGQIGKSFRNEITPGNFIFRTREFEQMELEFFFNPSDEKDWFSYWLNEVETFLQDKIQINKENYRVRSHEKDELAHYSTATSDIEFKFPFGWGELWGVAHRGNFDLNAHQEASKQDLTYLDPTTNQKVLPHVIEPSVGVERMMLAILWQAYHEEDLGEGNSRIVMKLPYNLAPYQIAVMPLQKQQNDQAQALYSNLLNNFDVTYDETGNVGKRYRRQDAIGTPFVITVDFDTPETNSVTVRERDSMEQVRINLDELEAYLKAKF
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTA_YERPB
Sequence: MKSQSKRTSRLFVFVGVVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTPLAPVQAATATEQEVPRYLTGLGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEIDPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTGLISQQELDTQSSLVRQSEGSVKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVFTLPESDIPAIMQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKARFNNEDDVLFPNQFVNARIKVDLLQNAVVVPTAAVQMGSEGNFVWTLDDANRVSKHLVTTGIQDSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPRSANTDTNPASAEKAAAEAEGSTPHQGRGRPANAPARSTTAAEKS
What are the official names of this protein?
Multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FEOC_SHIBS
Sequence: MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: RK2_LOLPR
Sequence: MAKHLYKTPIPSTRKGTVDRQVKSNPRNNLIHGRHRCGKGRNSRGIITARHRGGGHKRLYRKIDFRRNQKDISGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTKVPISMGNALPLTDMPLGTAMHNIEITRGRGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLVSQNCLATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGKAPIGRKKPTTPWGYPALGRRTRKRKKYSDSFILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DAPE_RICFE
Sequence: MYINYLKDLIGFKSVTPESDGAIEYIDDLLKQHGFKTEIKIFGDSKSEQATNLYAVFGSNEPNICFVGHVDVVPAGNHELWHNASPFKASHQDGKIYGRGAVDMKGAIACFLAASLDFIKNNTGFKGSISFLLTSDEEGKAKHGTKEMLQYIYDQGHKMDFAIVGEPTCEKEIGDTIKIGRRGSVNFKLNIEGLSGHVAYPHKANNPLPCLIKILNELTNIRLDKGTEFFQSSNLEVTNIDVGNNTSNVIPASTEASFNIRFNNLHSAETLAKQVEEIIKRYCKEYKVDYKLEYSSSADSFIQNPNDKIKDFADIVERVLKIKPEFSTSGGTSDARFVKDYCPLVEFGLLSETAHKINEYTKISDLQKLYDVYYNFLMEIL
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CY064_POSPM
Sequence: MFLQIVTSVLATGLLYALISVLQQNRTLSASLPPGPPGHWLFGNAPPRAFPYRHFAELTETYGPVFTLRFGRRIVCVIGRYQAAVDILMKHSAETSDRPRSVAANEIMSKGHRVLMTPAGERLKKYRRALHAFLQPSSSATYKPMQYKNAKNYVLDCLHDGRHHLYHGRKYAASVVMSVAYGKTTPTSYSDPEVLQINKSLARLGAALKPGAYLVDTYPILKYCPGYASHLRRYREEELALITKQANAVRELLAKGEAPPSFTAYLIENQERLGISDDELAYLSGAIFGAGSDTTAAALGIMTMAAACYPEAQARVQAQLDEVVGRDRAPTFEDEDLLPEVTAFVLEAYRWRPVSAGGFSHRATKDVVWNGYVIPAGAEIIGNHWAISRDPEVYPNPEDFKPARWLNEHGRIRNDLKFINFGFGRRVCVGQHVADQSLFINTALVLWAFRISQDAQCPIDTYAFTDTANVHPLPFSLHFEPRVKDMEAMLGAQAE
What is the function of this protein?
Cytochrome P450 monooxygenase that is able to use 4-ethoxybenzoic acid as a substrate for oxidation.
What are the official names of this protein?
Cytochrome P450 monooxygenase 64.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PEPX_STRMU
Sequence: MKYNQYSYIGTSVSQAEKELKELGFQISSQKTNKANLATFVSQVYFHNPDKDDVFKSIIADSQTDLATFLHSDRELTEEIFYTIALQLLEFTPYIDFDEAKTFIKHSHFPIIFQPKHFLLNFYQLLGTRTKNGMTLIDKLVSQGFLPADNHYRYFNGKSLATFDTNALIREIVYVEAPLDTDKDGQLDLIKVNIIRPQTKAKLPVVMTASPYHQGTNDKGADKKLHQMEGELTVKKAATITVTDSHFQALQVPSSNLPISPAQESFSYIDSYTLNDYFLARGFANIYVSGVGTKDSDGFMTSGDYAQIESFKAVIDWLNGRTTAYTSHKRDKRVMADWTNGLVATTGKSYLGTMSTGLATTGIKELKVIIAESAISSWYDYYRENGLVCSPGGYPGEDIDVLTELTYSRNLAAGDYLRNNAQYQKMLAEQVKQIDRTSGDYNQFWQDRNYLPHAHKIKAHVVYTHGLQDWNVKPNQVYYIFNALPEEIQKHIFLHQGQHVYMHNWQSIDFRESMNALLSEELLGLQNHFQLPTIIWQDNSQVQTWKKLNNFGSHQTRQFSLGQEKKIIDNHYPSSDFKLYSDDYHAFKHDLFLKKANEIAIDLPIQEDMLVNGQIKLNLTLKSSSNKGLLSAQVLDYGQKKRFSDLPTILEHNSIDNGQNFSREALRELPFKKAPYRIITKGVLNLQNRTDLLTIEDIFPNKWMTITFNLQASLYQLQKGDSLRIVLYTTDFEQTVRDNSNYILVVDLAKSTIEIPIA
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_STAAE
Sequence: MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDHFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERDSQKGIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: NU1M_SAGLE
Sequence: MFMANLLLVILPALVAMAFLTLTERKVLGYMQFRKGPNIVGPYGMLQPFADAMKLFTKEPLLPTTSTSMLYLTAPALALSIALLLWTPLPMPXPLMNFNLGLLFILATSSLAVYSILWSGWASNSNYALIGALRAVAQTISYEVTLAIILLSVLLMSGSFNLQSLITTQEHSWLLFPSWPLAMMWFTSTLAETNRAPXDLTEGESELVSGFNIEYAXGSFALFFMGEYMNIIMMNALTTTIFLAASYNMMTPETYSINFMAKALLLTTLFLWIRAAYPRFRYDQLMHLLWKNFLPLTLALCMWYISMPTLTSSIPPQM
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BIOH_SHIFL
Sequence: MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFISHPVEFCHLLVALKQRVLVVSES
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCA2_SCHPO
Sequence: MELYQKHLKDVYANFNKLAAVHGETTSNSVTFHVFQQLDSTNLTNYQLENVITQVKELDKGPKDYLYWVILGRCSAHLHVKMLDQLLEEAMIMSDNLHYWESIDKNWYSRVLFLIQSFPTRLYHICRNSIKSILQFQNFSNIFAKKNLFPKVSKSDVLLFPRDAFISQASLLSLIRHEYRGNAKRLRQLRDEHACKIGCLTRAIMSEGVSDAASSSGDKNGISAKADLKQVVSQWIQRLSQLQGQKIDNSESLPDILSITLDNLSHPTDEYFEAKAYFRPSAIERNWPKIFVTLLSAWLSTQIITKNRTSIRLWIDYLYSTAVDFYTNWIQKPILGIFDTIRSNRADSQITLLQTKSLESDMESLQRMVIDFVSDTSPAGINLDLVKQEVQQGDLTYVLQAYEHDLKTPIRTAVSGNLVRTLLIQLQKTKVDVEVALSGIDRLLKSQELVFATVGITPSLIFCYVIIRYVKANIFNNDTLSRAERRQRFRQSLRAAERILVRSQKMNSLDDMSYGLLVFQVNLMAIMSMDMGLSKDVAEDLLQDLEDIQSSSYGVQAQLRAVDRIYRLFKNSI
What is the function of this protein?
Involved in the mitochondrial expression of subunits 6 and 8 of the F0-F1 ATP synthase.
What are the official names of this protein?
Nuclear control of ATPase protein 2.
What is the protein family that this protein belongs to?
Belongs to the NCA2 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: ARGJ_ASPCL
Sequence: MAAFARMVKGQVRNYSAPLDMAIPASKQKYIPSSGSYPKGFLVSGTHVGVKASNTRFPDLALISSETPCSAAAVFTTNKFQAAPVQVSKKTLQERQGQGIRSVVINSGCANAVTGKGGYEDAVNMGKKVDECEGLSKPSTLVMSTGVIGQRLPISKILDKIPTAYANLASTHEAWLTTARAICTTDTFPKLLSRTFTLPSSPGHTYSLAGMTKGAGMIHPNMATLLGVLCTDAPIAPSALQSLLKYAVSRSFNSISVDGDTSTNDTIAVLANGAAGGAPINSASSDDYAAMQEILTSFAQSLSQLVVRDGEGATKFVTVRVQNSPDYDSARLIASTIARSPLVKTALYGRDANWGRILCAIGYTQGVAPGTVVPERTSVSFKPVDGSAVLKLLVNGEPEQVDEERASAILQEEDLEIVVDLGGGEKGELGGEEAVYWFCDFSHEYVTINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL21_LACDA
Sequence: MYAVIKTGGKQYKVAEGESIFVEKLDVQAGEEVVFDQVILVANGDDVKVGTPLVEGAKVVASVDKQGKEKKVVTFKYKPKKHSHSKYGHRQPYTKVTVKSIEA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SPAT4_PANTR
Sequence: MAAAGREKGYVTQTAAALDKSPSLSPQLAAPIRGRPKKCLVYPHAPKSSRLSRSVLRWLQGLDLSFFPRNINRDFSNGFLIAEIFCIYYPWELELSSFENGTSLKVKLGNWAQLEKFLARKKFKLPKELIHGTIHCKAGVPEILIEEVYTLLTHREIKSIQDDFVNFTDYSYQMRLPLVSRSTVSKSIKDNIRLSELLSNPNMLTNELKAEFLILLHMLQRKLGRKLNPEWFDVKPTVGEVTLNHLPAQASGRRYNLKVKRGRVVPVLPNIGSGGSSHREIHVKQAGQHSYYSAMKPIRNMDKKP
What is the function of this protein?
May play a role in apoptosis regulation.
What are the official names of this protein?
Spermatogenesis-associated protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: FDHE_SALEP
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLRMDLTARIKDANDQGKPPLDIHVLPRDKHWHTLLHSMIAELKPEMSGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GOLP3_DROME
Sequence: MNRSDGLVRRSVKPRENGGAEGGLNANTPDDNQDALDNLKDQEDNIDDGDSKETRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGCILIELGLRGRVMIEKSGMRRRGLCTRKLILKSDQQTGDVLLDEALKHIKETDPPETVQSWIEYLSGETWNPLKLRYQLKNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLSDNVVKCRLVKKIQDSVLSKWVNDPQRMDKRMLALIFLAHASDVIENAFAPLNDDDYEVAMKRVRELLDLDFEAESAKPNANEILWAVFMAFTK
What is the function of this protein?
Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi (PubMed:19837035, PubMed:24786584).  Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (By similarity).  May also bind to the coatomer to regulate Golgi membrane trafficking (PubMed:23720043, PubMed:24786584).  May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion (By similarity).  Also involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part (By similarity).  Functions in cytokinesis by regulating contractile ring formation and vesicle trafficking during cleavage furrow ingression (PubMed:24786584).  May also have a role in the intital steps of central spindle formation (PubMed:24786584).  Can also bind phosphatidylinositol-3-phosphate and phosphatidylinositol-5-phosphate in vitro (PubMed:24786584).
What are the official names of this protein?
Golgi phosphoprotein 3 homolog sauron, Protein rotini.
What is the protein family that this protein belongs to?
Belongs to the GOLPH3/VPS74 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Cleavage furrow. Note=Phosphatidylinositol 4-phosphate- binding and oligomerization participate in the recruitment onto Golgi membranes (PubMed:23720043). In dividing cells associates with vesicles in polar regions of the cells during metaphase and anaphase, and localizes to the cleavage furrow during telophase (PubMed:24786584).