PharMolix/UniProtQA huggingface dataset:
Protein: GARL_KLEP7
Sequence: MDNAIFPNKFKAALAAHQVQIGCWCALANPISTEVLGLAGFDWLVLDAEHAPNDVTTLIPQLMALKGSSSAQVVRVPTNEPIIIKRMLDIGFYNFLVPFVETAEQAAQAVASTRYPPEGIRGVSVSHRGNMFGTVPDYFAQSNKNISILVQIESQTGVDNVEAIAATEGVDGVFVGPSDLAAALGHLGNASHPEVQRAIQHIFASAKKHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADAFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: KAX65_PANIM
Sequence: DEAIRCTGTKDCYIPCRYITGCFNSRCINKSCKCYGCT
What are the official names of this protein?
Potassium channel toxin alpha-KTx 6.5, Pi-7, Pi7, Toxin-7.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVA_STAA3
Sequence: MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIHTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGIGPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAMLALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: IL12B_MOUSE
Sequence: MCPQKLTISWFAIVLLVSPLMAMWELEKDVYVVEVDWTPDAPGETVNLTCDTPEEDDITWTSDQRHGVIGSGKTLTITVKEFLDAGQYTCHKGGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFNIKSSSSSPDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQVEVSWEYPDSWSTPHSYFSLKFFVRIQRKKEKMKETEEGCNQKGAFLVEKTSTEVQCKGGNVCVQAQDRYYNSSCSKWACVPCRVRS
What is the function of this protein?
Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity.  IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues.  IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines.  IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
What are the official names of this protein?
Interleukin-12 subunit beta, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40.
What is the protein family that this protein belongs to?
Belongs to the IL-12B family.
What are the subcellular locations of this protein?
Secreted.
Protein: FNTA_YEAST
Sequence: MEEYDYSDVKPLPIETDLQDELCRIMYTEDYKRLMGLARALISLNELSPRALQLTAEIIDVAPAFYTIWNYRFNIVRHMMSESEDTVLYLNKELDWLDEVTLNNPKNYQIWSYRQSLLKLHPSPSFKRELPILKLMIDDDSKNYHVWSYRKWCCLFFSDFQHELAYASDLIETDIYNNSAWTHRMFYWVNAKDVISKVELADELQFIMDKIQLVPQNISPWTYLRGFQELFHDRLQWDSKVVDFATTFIGDVLSLPIGSPEDLPEIESSYALEFLAYHWGADPCTRDNAVKAYSLLAIKYDPIRKNLWHHKINNLN
What is the function of this protein?
Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex.  Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.  If X is Ser, Ala, Met, Cys, or Gln, then the protein is farnesylated, if X is Leu or Phe, then the protein is geranylgeranylated.  The alpha subunit wraps partly around the beta subunit forming part of the active site.  The beta subunit is responsible for isoprenoid and peptide-binding.
What are the official names of this protein?
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, PFTase/PGGTase I alpha, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_BORAP
Sequence: MKKSNFSNVNLSMGTGRRKSSVARVYIREGSGNIKVNNRDFDSYIQLENLRTMALSPLVLTNTLGKYDLYINVYGGGISGQSGAIRHGISRALFELDESNKMILRSNGFLTRDSRKVERKKFGQKKARKSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: SURA_AROAE
Sequence: MRRISSRLSLVLFAALSCATALFPAHAANPRSVEVDHIAAVVNNEVITARELRERVEQAIHQLNRQGTPQPPADVLERQLLERLVLERAQLQLARETSLQVDEATLERAIARIAESNRLTIAQLQAALEKDGVSWSRFRDNIRTEILLTRLREREVDNRIVVTDAEVDNFLANNADALSGEEFELAHILIRVPEAATQQQMAGLVARAETAKQRLNSGDDFARVAASYSDAPDAMNGGALGWRSRDRLPPLFAEAVRELSPGSVSPVLRSSAGLHIVKLLDRRGGAAAGPQQLEQTRARHILIRTSEILNDSEAESRLLGLRERVVNGASFAELAKAHSADLSSAKGGDLGWLSPGDTVPEFERTMNALKPGEVSAPVRSPFGWHLIQVEARRLQDVSDERKRNAARNALRERKADEAFEDWLRQLRDRTYVEYRTGKE
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: RFX4_HUMAN
Sequence: MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK
What is the function of this protein?
Transcription factor that plays a role in early brain development.  May activate transcription by interacting directly with the X-box.  May activate transcription from CX3CL1 promoter through the X-box during brain development.
What are the official names of this protein?
Transcription factor RFX4, Regulatory factor X 4, Testis development protein NYD-SP10.
What is the protein family that this protein belongs to?
Belongs to the RFX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTU_FRATH
Sequence: MAKEKFERSKPHVNVGTIGHVDHGKTTLTAAITKVMAEKNGGMARKFDEIDSAPEEKARGITINTSHVEYESPNRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPKIVVFLNKCDMVDDEELLELVEMEVRELLDQYEFPGDDTPVIMGSALRAIEGDEAYVEKIVELVQAMDDYIPAPERDTEKPFILPIEDVFSISGRGTVVTGRIERGVVNVGDEVEVVGIRPTQKTTVTGVEMFRKLLDRGEAGDNVGILVRGLKRDDVERGQVLCKPGSIKPHTKFEAEVYVLSKEEGGRHTPFFKGYRPQFYFRTTDITGAVELPEGVEMVMPGDNVKMTITLINPIAMDEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVH_ECOLI
Sequence: MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVKRNTEIFRGQIIDVTPSLYTVQLAGTSGKLDAFLASIRDVAKIVEVARSGVVGLSRGDKIMR
What are the official names of this protein?
Acetolactate synthase isozyme 3 small subunit, ALS-III, Acetohydroxy-acid synthase III small subunit, AHAS-III.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
Protein: ACCD5_MYCLE
Sequence: MTSVTDHSAHSMERAAEHTINIHTTAGKLAELHKRTEEALHPVGAAAFEKVHAKGKFTARERIYALLDDDSFVELDALARHRSTNFGLGENRPVGDGVVTGYGTIDGRDVCIFSQDVTVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHYVASGEQDAFDWVRDVLSYLPSNNFTDAPRYSKPVPHGSIEDNLTAKDLELDTLIPDSPNQPYDMHEVVTRLLDEEEFLEVQAGYATNIVVGLGRIDDRPVGIVANQPIQFAGCLDINASEKAARFVRVCDCFNIPIVMLVDVPGFLPGTEQEYDGIIRRGAKLLFAYGEATVPKITVITRKAYGGAYCVMGSKNMGCDVNLAWPTAQIAVMGASGAVGFVYRKELAQAAKNGANVDELRLQLQQEYEDTLVNPYIAAERGYVDAVIPPSHTRGYIATALHLLERKIAHLPPKKHGNIPL
What is the function of this protein?
Component of a biotin-dependent acyl-CoA carboxylase complex.  This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate.  When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA.
What are the official names of this protein?
Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase beta5 subunit, Acetyl-CoA carboxylase, ACC, Propionyl-CoA carboxylase, PCC.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
Protein: APT_YERPA
Sequence: MTVSASKTAQQLKYIKDSIKTIPDYPKAGILFRDVTSLLENPKAYSASIKLLSEHYSESGVTKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRETISESYELEYGTDTLEIHTDSIQPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVVHAAFIINLPELGGEARLTQQGIHCYSLVSFDGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANE_STAA8
Sequence: MLPHGLIVSCQALPDEPLHSSFIMSKMALAAYEGGAVGIRANTKEDILAIKETVDLPVIGIVKRDYDHSDVFITATSKEVDELIESQCEVIALDATLQQRPKETLDELVSYIRTHAPNVEIMADIATVEEAKNAARLGFDYIGTTLHGYTSYTQGQLLYQNDFQFLKDVLQSVDAKVIAEGNVITPDMYKRVMDLGVHCSVVGGAITRPKEITKRFVQIMED
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: ACT_CHLRE
Sequence: MADEGEVSALVCDNGSGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFFNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILMERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATALSSSALEKTYELPDGQMITIGNERFRCPEVLFNPNMIGMEAVGIHDTTFNSIMKCDVDIRKDLYNNIVLSGGTTMFPGIADRMSKEITALAPSAMKIKVVAPPERKYSVWIGGSILASLSTFQQMWIAKSEYDESGPSIVHRKCF
What is the function of this protein?
Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CXB1_HUMAN
Sequence: MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction beta-1 protein, Connexin-32, Cx32, GAP junction 28 kDa liver protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Beta-type (group I) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: RS14_PARPJ
Sequence: MAKLALIEREKKRARLAAKYAPKRAELKAIIGDMSKSDEEHYAARLELQQLPRNSNPTRKRNRCAITGRPRGTFRKFGLARNKIREIAFRGEIPGLTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: FB203_ARATH
Sequence: MKIAVKKSCRNLSELPQELLYKILGLLPTRNVVSTSLISHQRRSQFHWMERLKFRYPRLLLDNRVPDAENEAENLVPGPSRCYHEDPKSCIIQEQIFLPYTSGSFHVQTRISSQRLIHNQHRKCQLRCVVQLSSFCLLSLQQIRLQRC
What are the official names of this protein?
F-box protein At3g55900.
Protein: Y1126_METTH
Sequence: MPSESFLKKIMGRDLQIMENDADMGPEYGDHADEPEIIADFTEYSPFHIGHRHCMMEAKRRVPEGLFVAVIPGPLERNGRGLPYMMTREARAAIAIRAGADIAVEGPPMGVMGSGQYSLCLAGMFRALDADWIPRGYRPIPGFEEVLRRINLGHRVVPRPHRIVDLDKGETLLKGPLEEDNYVITSLARALGKLGFDFRGKFIFVERIGGVSGTEIRRAVSDGDLQRVAGMLPPETMDVLSEEIEAGRAPLHDMRLEDEIIRNASEPGMDELMDLNLFDEVTASALIRGRPYMTLREVEEAIPPSFSRHHRQRILSVLEAKVHKGLVHKYIENYPSVIRILGFKDKQILKEFKDRIPHRRLEIWQ
What are the official names of this protein?
Uncharacterized protein MTH_1126.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
Protein: TPS4_MEDTR
Sequence: MLLNSSFISLPSFFKSQELGRTNLLIHRNGSPLLCYATNTNVSQRKSANYQPNIWNYDILQSLKHDYEDARYVDRSRRLQEEVKRMIKDENVNILELIDTVKQLGLSYHFEEEIGEALDRFLSLEKCSGRNNFGRSLHETALRFRLLREYGYDISPDIFEKFKDHNGNFKACLVQDIKGMLSLYDASFLSYEGEQILDEANAFTSIHLKDLSEGRSSILIDQVNHSLELPLYRRVQSLEARWFIDSYENRKDANKVLLEAAKLNFNIVQSTLQQDLKEMSRWWKGMGLAPRLSFGRDRLMECFFWAAGMTPFEPQFSNIRKGLTKVCSLITLIDDIYDVYGTLDELELFTTAVESWDINAIQILPEYMKIFFLALYTTVNDFTYDTIKETGHDILPYLVKVWSDMLKAFLQEAKWCHNKHMPKFDDYLNNAWVSVSGVVLLTHSYFLLNRNITKEGLGYLENCPMLLQTPSIIFRLCNDLATSSAELERGEGANSIICYMNENGVSEEVAYKHIQNLLDQTWKKMNKDRVINSPSSKYFSETIINLARISHCTYQYGDGHGAPDTLAKNRIKALILEPIN
What is the function of this protein?
Promotes the emission of terpenes volatile organic compounds (VOC) in response to damage mediated by arthropod herbivores (e. g.  Spodoptera exigua), probably to attract natural enemies of the herbivores.
What are the official names of this protein?
Tricyclene synthase TPS4, chloroplastic, (E)-beta-ocimene synthase, MtEBOS, MtEbetaOS, Terpenoid synthase 4, MtTPS4.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RS6E_THESM
Sequence: MATFKLVISDTKTGVAKQIEITGAEADKLIGLRIGDEIEAKELGFNLSEIFGSEIPGDVKLKITGGTDKDGFPMRPDVHGPRRVKILISRGPGFRPQERGERRKKTVRGNTISPEIAQINVKIVYP
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: DNLJ_BAUCH
Sequence: MKQIEQYIEQLRQQLRYWNFLYYAKDAPEVSDVEYDWLMMKLRELERQWPDLKTADSPTQHIGYKAQSKFRKVIHEVPMLSLDHIFNDTSFLAFDRRIRNRLQYGNNYLTYCCELKFDGIAVSLLYKHGKLIRAATRGDGHIGEDVTDNIRTICSIPLQLKDDGHIPRLIEIRGEVIMSEDAFRHLNETAKKNKSKRFANPRNAAAGSLRQVDPSITATRLLSFFCYGVGRIDSKKIPAAHLELLQQFKIWGLPVSNYRRYCVGHQEVLDFYSYVSKVRSKLGFNIDGIVIKVNALVQQQQLGFVARAPRWAIAYKLPANEQLTEIQNIDFQVGRTGIITPVARLKPVYISGAYISNASLHSFAEIKRLGLRIGDTVVIRLAGNIIPQIVNVVVSKRSIKTSPVLYPLYCPVCGSKVKQNNKEKTIICTAGMICSAQLKEALKHFVSRRAMNIYGMGGKIIDQLVDLKIIQNPVDLFRLNQDQLTCLKNMGQKKTKKLLDAIEYAKKTTFARFLYAIGIREIGETKAAYLADYYKHIDALMAADIESLTKIQDIGIIVATNVLNFFHNKHNIAIIEELCSPKIGIKFLSTLEKNNYFSGKNIVFTGTLAFLSREEAIDMLIALGARIRSSVSSKIDLLIAGKNTGFKLTKAKQLQIKIIEEAEFYQILGIR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GLMM_AERHH
Sequence: MARKYFGTDGVRGKVGEYPITPDFVMKLGWAAGKVLSKKGTRKVLIGKDTRISGYMLESALEAGLSAAGLKAILMGPMPTPAVAYLTRTFRAEAGIVISASHNPYYDNGIKFFSADGTKLPDEVEMAIEAELDHELKCVESAELGKALRIDDAAGRYIEFCKSTFPSNLSLEGLKMVVDCGHGATYHIAPSVFRELGAEVIAIGCSPDGLNINDGVGSTAPEALAAKVLECKADLGVAFDGDGDRLVMVDNTGYIIDGDEILYIIARDALRNGRLKGGVVGTLMANMGLELALQTLGIPFARAKVGDRYVLEMMNEKGWRIGGENSGHIICLDQTTTGDGIVAALQVLTAICTAEMPLAKLRSGMNKFPQVLVNVRFAEGRDPLAADAVQQEVAKVEQELAGRGRVLLRKSGTEPLIRVMVEGEHEQQVRDMAQRIAQQVESAF
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y1834_LEPBL
Sequence: MSQFSVLNVGFGNIVLVSKIVSIIHSDSASAKRIRNEAKSNNSLIDATQGKKTRSIIVTDSNHLILSNLRVESLAKRIESSDNSIASEEEDLD
What are the official names of this protein?
Putative regulatory protein LBL_1834.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: PPAE_BOMMO
Sequence: MFLIWTFIVAVLAIQTKSVVAQSCRTPNGLNGNCVSVYECQALLAILNNQRRTQQDEKFLRDSQCGTKNSVPAVCCPCNAADGQQGNCVNINSCPYVLQLLKNPNEANLNYVRGSVCQGSEQQSICCVTAPQSTAVTTTPRPKRVHACQSEMTATPPNPEGKCCGRDIAVGDKIVGGAPASIDSYPWLVVIEYVRLERTMLLCGGALISGKYVLTAGHCVKGAILDVGTPKTVRLGEYNTTNPGRDCVSVSAGGTDCTDPLVKIGIEKTIPHPDYQPYHFLRKHDIGLIRLQSIAPFTDFIRPICLPSTDYTVNPPSKFALTVAGWGRYLQFDNGTVRSSKIKLHVTLPFVQRDVCEANQKPLRNGQRITLWKGQMCAGGEAGKDSCKGDSGGPLMYEHSKKYEAVGIVSFGPEKCGQIDIPGVYTNVYEYLPWIQNTIEP
What is the function of this protein?
Endopeptidase with selective post-Arg cleavage site (PubMed:4197814, PubMed:4197815, PubMed:10066809, PubMed:7981662).  Activates prophenoloxidase (PubMed:4197814, PubMed:4197815).  Has a probable role in the melanization process as part of the innate immune response (Probable).
What are the official names of this protein?
Phenoloxidase-activating enzyme, Prophenoloxidase-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
Protein: RS9_NITSB
Sequence: MSRIYATGKRKTAVAKVWLTKGSGKITVNGMSLDEWLGGHEALKLRVRLPLALTKMSESVDVVATTLGGGYSAQADALKHGISKALCAMDDNLRSVLKPHGLLTRDARVVERKKYGKHKARRSPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: DDX52_RAT
Sequence: MDSYDLFRRLGAGAKFDVKRFSADATRFQVGKRKFGSDSSETVKGLDFFGNKKSVSDECGGLQTQQELQNEETTEGGLLERSKEPKKKKRKKMTADVPAQEDLDGTIQWTSSVEAKLQDKKANGEKKLTSEKLEHLRKEKINFFRNKHKIHVQGTDLPDPIATFQQLDQEYKISPRLLQNILDAGFQVPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPTNKGFRALVISPTRELASQIHRELIKISEGTGFRIHMIHKAAIAAKKFGPKSSKKFDILVTTPNRLIYLLKQEPPGIDLTSVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSPKVRRAMFSATFAYDVEQWCKLNLDNIVSVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNRGKAVTFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKYFLEQAKQKKVAGQNSKKKETLKGKS
What is the function of this protein?
Required for efficient ribosome biogenesis.  May control cell cycle progression by regulating translation of mRNAs that contain a terminal oligo pyrimidine (TOP) motif in their 5' UTRs, such as GTPBP4.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX52, ATP-dependent RNA helicase ROK1-like, rROK1L, DEAD box protein 52.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL2_ECOK1
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SEC11_YEAS1
Sequence: MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNRNTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Secretory protein 11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.