PharMolix/UniProtQA huggingface dataset:
Protein: MDM12_BLAGS
Sequence: MSIDIDWERATSGPDGELLAERIRSFIHDKFQQIVLPRFIRSVQVTSFNFGTIPPELEIRDLCDPFPDFYEEDDNENFSESSEEQSPTREPVDRYGSKVESWQANSPGSLEDHMQGRMGFNGPLRMPPGEENTGISPLRSPMNFGDINPYLFPRSRTPGIPGGTSNLGYYMPLSGLSGSQTPLGTVARGSPFSGGWPDVHGARPSRRRSEVEPDSAQSRPSTANTGNTLLSRGSMSSGDPRHSHHSQGVPGSDHGQVLEPNMPPTSSDAPLDDLPPRRMREQKAEDFQVFCRTKYAGNISLSLTAEILLDYPMPSFVGLPLKLNITGLTFDAVAVIAYIRRRIHFCFLSPEDADALIGPEIGSGGGEDTLEPNSPRRKPLSLLREIRVESEIGRKENGKQALKNVGKVEKFVLEQVRRIFEEEFVYPSFWTFLV
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: SCD5_HUMAN
Sequence: MPGPATDAGKIPFCDAKEEIRAGLESSEGGGGPERPGARGQRQNIVWRNVVLMSLLHLGAVYSLVLIPKAKPLTLLWAYFCFLLAALGVTAGAHRLWSHRSYRAKLPLRIFLAVANSMAFQNDIFEWSRDHRAHHKYSETDADPHNARRGFFFSHIGWLFVRKHRDVIEKGRKLDVTDLLADPVVRIQRKYYKISVVLMCFVVPTLVPWYIWGESLWNSYFLASILRYTISLNISWLVNSAAHMYGNRPYDKHISPRQNPLVALGAIGEGFHNYHHTFPFDYSASEFGLNFNPTTWFIDFMCWLGLATDRKRATKPMIEARKARTGDSSA
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.  Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15610069, PubMed:15907797, PubMed:22745828).  Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069, PubMed:15907797).  Involved in neuronal cell proliferation and differentiation through down-regulation of EGFR/AKT/MAPK and Wnt signaling pathways (PubMed:22745828).
What are the official names of this protein?
Stearoyl-CoA desaturase 5, Acyl-CoA-desaturase 4, HSCD5, Stearoyl-CoA 9-desaturase, Stearoyl-CoA desaturase 2.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FMT_SHEWM
Sequence: MKPLNVIFAGTPDFAARHLQALINSEHNVIAVYSRADKPAGRGKKLQASPVKMLALENEIPVYQPTSLRDEQAQAELASLNADIMVVVAYGLILPKVVLDTPKLGCINVHGSILPRWRGAAPIQRALWSGDTETGVTIMQMDIGLDTGDMLLKTQLPIEDSDTSASLYEKLAEQGPEALVEALTGLAKGELAAEKQDEALANYAEKLSKEEAELDWNKSAAQLWREIRAFNPWPISHFSHQDASIKVREAHVSQSKSQAPAGTIISAGKEGIEIATGDGVLTLLNMQLPGKKPLSVADILNSRSEWFTPGTVLNSTKEAE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: LGI4_HUMAN
Sequence: MGGAGILLLLLAGAGVVVAWRPPKGKCPLRCSCSKDSALCEGSPDLPVSFSPTLLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQCDCRVLWLLQWMPTVNASVGTGACAGPASLSHMQLHHLDPKTFKCRAIELSWFQTVGESALSVEPFSYQGEPHIVLAQPFAGRCLILSWDYSLQRFRPEEELPAASVVSCKPLVLGPSLFVLAARLWGGSQLWARPSPGLRLAPTQTLAPRRLLRPNDAELLWLEGQPCFVVADASKAGSTTLLCRDGPGFYPHQSLHAWHRDTDAEALELDGRPHLLLASASQRPVLFHWTGGRFERRTDIPEAEDVYATRHFQAGGDVFLCLTRYIGDSMVMRWDGSMFRLLQQLPSRGAHVFQPLLIARDQLAILGSDFAFSQVLRLEPDKGLLEPLQELGPPALVAPRAFAHITMAGRRFLFAACFKGPTQIYQHHEIDLSA
What is the function of this protein?
Component of Schwann cell signaling pathway(s) that controls axon segregation and myelin formation (By similarity).
What are the official names of this protein?
Leucine-rich repeat LGI family member 4, LGI1-like protein 3, Leucine-rich glioma-inactivated protein 4.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSJ_MANSM
Sequence: MSNTTNPLPPETEQLLAKLNPIQLAWLSGYAWAKAQGEDAGTNVTNKNAASTLVTEDKPLNVTVLSASQTGNANGVANQLAERLKAEGVNVTRKALKEYKAKTIGDEQFVLLVTSTQGEGEAPEEGVPLYKLLHGKKAPNLANLEFAVLGLGDTSYPNFCQAGKDFDKRFEELGAKRLLARADADLDFKSTADKWIQDVVEAVKAKSAVSASVVASVVSASSAQSAVNYSKENPYTAKLITNQKITARDSAKDVRHFEFDLSGSGLQYKAGDALGVWAENDPDLINEVLGLLKIQPDESVQLNGKSLDIHGALLSRLELTQNTPAFVKGYAQLANNKKLTALVSSDKKLADYVNDTPIVDVLHDFPAKISAQQFADLLRPLTPRLYSISSSPEEVGEEVHLSVGVVRFEHEGRARTGVASGFLADRVEEDGEVKIFVEPNDNFRLPQDKSKPIIMIGSGTGIAPFRAFLQQRQAEEAEGKNWLIFGNQHFATDFLYQAEWQQFVKDGYLHKYDFAWSRDQAEKIYVQDKIREKSTALWQWLQEGAHVYVCGDASKMAKDVENALLEVIAREGKLTPEDAEEYLNDLREDKRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: YGWC_SCHPO
Sequence: MNALNKIPFTRALYHFSRFRSFTTSGWIMSGHNKWSKIKHKKSANDQARSLQIGKLSQGIILAVRQEGANPELNMRLATLLESAKKISMPKSGIENAINRGLGTAGSEGSQVHFIEYEAMHPSGVGLIVEAVTDNRARAASSIKHILRNHGASLSTVKFLFSKKGKVEVNLPPEKRDSMKFEDVLDDAIEAGAEDIVNRPKEYIDEEDEGEFLILTEPSSLNQVAHHFRSKNYEIKDSRLIHIPLEETAIDVPAKDSVREDIQKLIDDLYENEDVMFIHLSILNSHFLPILDE
What are the official names of this protein?
Probable transcriptional regulatory protein C8D2.12c.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MTRA_METMP
Sequence: MADKKAPAAGWPVANGEYVVGNPESCVAVVTLGSHGLDQAAIDAGAAISGPCHTENLGIEKVVANYISNPNIRFMVITGSEVQGHITGQCIKALYENGIGDDGGIIGAKGAIPFMENVGTEPVGRLQSQIVECIDLIDVEDTGKISDAIKNCISKDPGAFEEEPMVIELEGGAAAAGEESTSIKPTSPEMALLEARMRIVSEKMNEAAMIAKFNSGYYNGKIQGIAIGLFLSIVIFSLL
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit A, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A.
What is the protein family that this protein belongs to?
Belongs to the MtrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y1415_PSEAB
Sequence: MSEATAATAAIGKCWSVYLVRAENGALYCGISDDPLRRFDTHCSGKGARFFHSSPARALVYVEACASKGDALRRERAIKALSKRAKERLLVGVPVLREVGEPAI
What are the official names of this protein?
UPF0213 protein PA14_14150.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: DAPB_THISH
Sequence: MTNICIVGAGGRMGRTLIEAIQQAEGLDLTVATERAGSSLIGADAGELAGVGRLGVAISEDPAAQVAAFDVLIDFTRPEGTLAHLEICRKAGRAMVIGTTGFTEAQKQTIREAAKEIPVVFAPNMSVGVNLCLKLLDLAARVLGDEVDIEVIEAHHRHKVDAPSGTALRMGEVVAEALGRDLAQCAVYGREGHTGERERKTIGFETIRAGDIVGEHTVMFAGIGERVEITHKASSRMTFAKGAVRAAAWLKGRSAGLYDMQDVLDLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_THETH
Sequence: MSTKNAKPKKEAQRRPSRKAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSGKEQRILAKTIKRARILGLLPFTEKLVRK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: NUOH_ROSDO
Sequence: MADFFTTPGGIAVLILAQVLAVIGFVMVSLLFLVYGDRKIWAAVQMRRGPNVVGTFGLLQTVADALKYVVKEVVVPAGADKTVFMLAPMTSFVLALLAWAVIPFNDGWVLSDINVAILFVFAISSLEVYGVIMGGWASNSKYPFLGSLRSAAQMISYEVSLGLIIIGVIISTGSMNFGGIVAAQDGPYGFFSWYWLPHFPMVFLFFISCLAETNRPPFDLPEAESELVAGYQVEYSSTPFLLFMAGEYIAIFLMCALTSLLFFGGWLSPIPGLPDGVFWMIAKMAFFFFLFAMVKAITPRYRYDQLMRLGWKVFLPFSLVWVVFVAFAAKFEWFWGAYARWGMGG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_PYRCJ
Sequence: MGGLKKPKKKYLAGKPKKIWNKQLLLEELQLMGEYGLRNKKELWLARARLKWIVRRARALLSMTAEERAPLEVPFKEKLYKMGFIEDPNVPLDRILSLDVRAILERRLQTLVFRMGLAKSIHHARQLVVHGHVLVAGRRVTSPGFLVPRELEDKITIEQ
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GLK_BRUA2
Sequence: MQAIIDAEQSFKFPVLVGDIGGTNARFSILVDSNAEPKEFPVLQTADYATIDEAIQHAILDQTAIQPRSVILAVAGPVDGDEIDLTNCDWVVRPKKMIADLGFEDVTVLNDFEAQALAVVSLEGHHMEQIGGKPEEAVATRVVLGPGTGLGVAGLFRTRHAWVPVPGEGGHIDIGPRTERDYQIFPHIERIEGRVTGEQILSGRGLRNLYLGICAADKITPTLETPVDITSAGLDGSNPQAAETLDLFATYLGRLAGDLALIFMAHGGVYLSGGIPVRILSALKAGSFRATFEDKAPHKAIMRDIPVRVITYQLAALTGLSAFARTPSRFEVSTEGRRWRMRR
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_PSYA2
Sequence: MNVFTTLQQFVPQQKISKVAGRLAASRHPWVKRTFIRSFAKAYDVSLDEYERQSLNAYESFNDFFTRELQDNARIIDASINGIVSPADGMISQLGQIHDHKLLQAKGRDYDIGQLLADSADGDYFADGSFATVYLAPSNYHRVHMPFDGTLIKTRYVPGTLFSVNNTTAANVPDLFARNERLVCLFDTAYGKAAVVMVGAMIVAGIETVATGKISRTDDIQEADHDMSFKKGDELGRFYLGSTAIVVLPKAAKTEWQATMQHGSTVQMGQLLANAKI
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FABZ_VIBC1
Sequence: MTTEKKTMNISEIQELLPHRYPFLLIDRVIDFQEEKYLHAIKNVSVNEPQFTGHFPQLPVFPGVLILEAMAQATGLLAFKSFGAPTENELYYFASVDGAKFRKPVVPGDQMIIEVEFLKERRGIAAFKGVAKVDGEVVCSAELKCARREF
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLII_MOUSE
Sequence: MEATGVLPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNHLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNGIDSIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMMALQTLHLRNTQRTQSNLPTSLEGLSNLSDVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIAELSLCIDQWVHLETLNLSRNQLTSLPSAICKLTKLKKLYLNSNKLDFDGLPSGIGKLTSLEEFMAANNNLELIPESLCRCPKLKKLVLNKNRLVTLPEAIHFLTEIQVLDVRENPSLVMPPKPADRTAEWYNIDFSLQNQLRLAGASPATVAAAAAVGSGSKDPLARKMRLRRRKDSAQDVQAKQVLKGMSDVAQEKNKNQEESIDARAPGGKVRRWDQGLEKPRLDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDTHYVTRMYRVYGKKNIKLEPVPLKGSSLDPRFVFLLDQGLDIYVWRGAQATLSNTTKARLFAEKINKNERKGKAEITLLVQGQEPPGFWDVLGGEPSEIKNHVPDDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKKRPKVELMPGMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHTVVSRSLEGTEAQVFKAKFKNWDDVLTVDYTRNAEAVLQGQGLSGKVKRDTEKTDQMKADLTALFLPRQPPMPLAEAEQLMEEWNEDLDGMEGFVLEGRKFTRLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKTEDKEGKASAEAREGEEAAAEAEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFIIHRGKRKVTQGTLQPTLYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNTMFDASYSKQVINEGEEPENFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHTRSKEHERPRRLRLVRKGNEQRAFTRCFHAWSTFRQAPA
What is the function of this protein?
May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1.  Involved in estrogen hormone signaling (By similarity).  Essential for early embryonic development.  May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation.
What are the official names of this protein?
Protein flightless-1 homolog.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell junction, focal adhesion. Note=Colocalizes to actin-rich structures in blastocysts and, together with HRAS, RHOA and CDC42, in migrating fibroblasts. Localizes to centrosomes.
Protein: APC4_DICDI
Sequence: MKDFVLLNDKILPNDVKCYSCCTTMDLIALVTKDDQIVIHRFLTWQKLFTINHMSTTINDNNTNNNNNNNNNNNNNNNDNNNDNDKSNKSIVSIQWSPNGKMISIGCEDGSIFIYNIENAKLINKSHNHKHPIHKLAWIKEVSQQRSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNKNGSTKCNNNYVSPPLFLSQIKQNMNLFPSISYYFENSKEENIYLGGDIYDRPFDILICCDSIGVISLLAFGLFKIVTIDLLSLLKQKYSNTHFLIKPSKSLKILDITLTESLNKLSVMIETDNGLFLSVTIDTSILLEKRNEIHEISLQYFLLFQLQQSLDIHIKEITEKWKETQQQLSTKWVEFEKVLSDYGFSSSIEQELIDLLMCGVPSPPTNQFIVNNINIKKLKLTESNCNSIREILIKYILPSFLNIFHIITVLHNNSLENDGYKGLLDTNTVKNILDYCGSFGMRLQSLETLICGIESHYTSFFSWLYKVQCTLNEIQPDRKLSLPFNELSIMSLLKKGLKFDLLFSTSTLFSSSSSSSPSSPPSNNNSPTFSSSSSINNNNNNNNNELNQSGNIGFSNNNENLEFQYKDLKGNFHDLFKDFSSKIFETFNEITIVLPSLFKFENVIPFCLYDKNDTSVSHKFNCSLISHPNDTIYLSIYTTLSNSNRLFICKREDKLNWSFTCYQLNEKYSILDCKFYNNSSLMALVSEDIIKANQKKSTRKNTYLKQYQYKTDDNDDSDNREYIKLDVNIPQSTILLDLLDSFKSREIILKSRISPITFELSTSRKISATFIGKRRVALYDLAEDEEEEEEGEEEDICLVR
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
What are the official names of this protein?
Anaphase-promoting complex subunit 4, APC4.
What is the protein family that this protein belongs to?
Belongs to the APC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBB_LEMMI
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSITGGTITNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQPVSPAWGAEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRISAGLAENLSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAIGWLGHPVFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTKRQAV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PYRH_CORGL
Sequence: MTTSSEQPRTGYKRVMLKLGGEMFGGGKVGVDPDVVDNVARQIAEVAKTGAEIAVVIGGGNFFRGAELQQRGMDRARSDYMGMLGTVMNCLALQDFLGQHGVECRVQTAINMAQVAEPYLPLRAERHLEKGRVVIFGAGMGMPYFSTDTTAAQRALEIGCDVLLMAKAVDGVYSDDPRTNPDAELFTEITPKEVIEKGLKVADATAFSLCMDNKMPILVFNLLTEGNIARAISGERIGTLVES
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_RICAH
Sequence: MSKFSFNIHHQHKKARSGIIATAHGEIRTPAFMPVGTRGTVKAMLPESVAETGADILLGNTYHLMLQPSAERIARLGGLHKFMNWDKPILTDSGGFQVMSLSKLRKITEEGVSFSSHINGDKYMLTPERSTAIQYLLGSTITMAFDECTPYPVTFEEAKTSMQLTTRWAHRSRNAFVKREGYAQFGIIQGSVYEELREQSAKGLVELDFDGYAIGGLAVGEGQELMFKVLDYAPDFLPQNKPRYLMGVGKPADIIGAVNRGIDMFDCVIPTRSGRNGQAFTKYGTVNICNSKYSGDNEPLEHDCPCPACTNYTKAYLHHLVRIGEILGSMLMTWHNLTYFQNLISRIREYIKLGKDFDFYS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TILS_RICBR
Sequence: MLYEKFEHNINNLIGGFGLSKIAIAVSGGSDSVALLYLANIWAKKNNIELFVLSVDHNLRDQSKQEIEYIQNTANDLGLKFYSLFFDHQNNFSNLQERARKGRYDLMTSLCQKLDILVLLTAHHEDDYIENFCLRLERKSGVFGLSSSSVNWHNNTQIIRPLFNIPKSELVNYLATNNIKWFEDQSNLSTKYRRNTIRQKLAKEEVYIKDDIITQQIKVNELIENKFKPELISAIAESVKISEYGFAFLDLIKFSGFSQEVRVQLINFLLIIISGQQRSARFYSVEPILKLIRQSLDFKNTLHGCVIKRMQNKLLIYREFGKKLPESKLLLDKQLVWDNRFRITKNHNIENCVATYLSLEDYKIIKEKLDLEVLKNLSCGNHNAILFTLPIVKILEKVVAIPHISYYDNDIKSFNVSFAPDFTSRFTHFY
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGHB_AOTNA
Sequence: MEMLQGLLLCLLLSTGGAWASNEPLRPLCRPTHAILAAEKEGCPVCVAFNTTICAGYCSSMVRVLQTVMPPLPQLVCNYHELRFTSVRLPGCRRGVNPVVYFPVAVSCRCALCRRSYSDCGNLKSEPLGCDYHTSQDSSSKDPPRNLTSPSQLPEPADAPLVPQ
What is the function of this protein?
Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
What are the official names of this protein?
Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: GTPC1_HELPJ
Sequence: MALVKEVLEVLNRLSPFELQESWDNSGLNVGSGNSEFSQIIACLEITLQIALNAQENALIITHHPLIFKPLKTLNDEAYPGNILKILIQKNISVISMHTNFDKTHLNKHFARALLRFDGLIEKGLMLVKENANIEFDVLLEKIKLSLGVGQLACVKSSQMIKDLAFVCGSGASMFSSLKAQSCLITGDVKYHDAMIAQSLGISLIDATHYYSERGFALIVAEILHSFNYLVTIENFKNPLQII
What is the function of this protein?
Converts GTP to dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase 1 type 2, GTP cyclohydrolase I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: YOPN_BPSPB
Sequence: MHVVELRSTNHKDIDADFVLNAKQTYIESVLNIRKMIVNAKTEDDLHGAKIEIAALLKDLNRVLLGGDGLKRSIENNPHFRSLIHFVKNLKRHIAIEFEEFIYQP
What are the official names of this protein?
Uncharacterized protein yopN.
Protein: HSCA_METCA
Sequence: MLLQISEPGAGVKPQRRLAVGIDLGTTHSLVATVRDEQTVVLGDAQGRVLLPSVVRYLGAGAIEVGYEAKARQAEDPENTFVSVKRYMGRGLGDLASHHGAPYRFVEGEGMVQFDTRAGRISPVQVSAEILKVLRDRAVAELGGELAGAVITVPAYFDEAQRQATKDAAKLAGLEVFRLLNEPTAAAVAYGLDNAAEGVYAVYDLGGGTFDISVLKLTRGVFEVLATNGDPALGGDDFDRAVYDWLLAQSGLNGLSSSDASLLLTASRAAKERLSEQTEATVDTMLSDGSRIVATLSRDTFAELTAGLVKKTLTPVRKALRDAGLAIDDIKGVVLVGGATRMPCIREAVAEFFQQTPLTDLDPDKVVALGAAMQANLLAGNRAGGDWLLLDVIPLSLGIETLGGLCEKIVPRNTTIPVARAQEFTTWKDGQTAMSIHVVQGERELVSECRSLARFELRGIPPMAAGAARIRVTYQVDADGLLNVTAAEQTSGVEARIEVKPSYGLSDAEVARMIEDSYLHARDDLEARRLQEQKVEAARLIEATESALTEDGGLLTEQELEVLVKGLQVLKGAMEGSDWQAIKNAADALNEASTEFAGRRMDHSIKAALTGQKLESLGV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: BIOB_ECOHS
Sequence: MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.