PharMolix/UniProtQA huggingface dataset:
Protein: C11B1_HUMAN
Sequence: MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRRPGNRWLRLLQIWREQGYEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTFRAIN
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids (PubMed:18215163).  Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11-deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively (PubMed:18215163).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule.  Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin) (PubMed:18215163).
What are the official names of this protein?
Cytochrome P450 11B1, mitochondrial, CYPXIB1, Cytochrome P-450c11, Cytochrome P450C11, Steroid 11-beta-hydroxylase, CYP11B1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: H2A2_PICST
Sequence: MSGGKGKAGSSEKASTSRSAKAGLTFPVGRVHRLLRKGNYAQRVGSGAPVYLTSVLEYLAAEILELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQSLLPAKKAKPGKASQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TBB1_PARTE
Sequence: MREIVHIQGGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGRYVPRAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVVRKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKVREEYPDRIMETFSVVPSPKVSDTVVEPYNATLSVHQLVENADECMVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMIGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMCAADPRHGRYLTASALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNIKSSICDIPPKGLKMAVTFVGNSTAIQEMFKRVAEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEGEQ
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PRE6_ARATH
Sequence: MSSRRSSRSRQSGSSRISDDQISDLVSKLQHLIPELRRRRSDKVSASKVLQETCNYIRNLHREVDDLSDRLSELLASTDDNSAEAAIIRSLLNY
What is the function of this protein?
Atypical and probable non DNA-binding bHLH transcription factor that regulates light-mediated responses in day light conditions by binding and inhibiting the activity of the bHLH transcription factor HFR1, a critical regulator of light signaling and shade avoidance.  Forms non-functional heterodimers with HFR1, causing liberation and activation of PIF4 from the transcriptionally inactive HFR1-PIF4 complex.
What are the official names of this protein?
Transcription factor PRE6, Basic helix-loop-helix protein 163, AtbHLH163, bHLH 163, Protein KIDARI, Protein PACLOBUTRAZOL RESISTANCE 6, bHLH transcription factor bHLH163.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RP22_VACCC
Sequence: MNQYNVKYLAKILCLKTEIARDPYAVINRNVLLRYTTDIEYNDLVTLITVRHKIDSMKTVFQVFNESSINYTPVDDDYGEPIIITSYLQKGHNKFPVNFLYIDVVISDLFPSFVRLDTTETNIVNSVLQTGDGKKTLRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMVTGVEIADRSVISVAD
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG133, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 22 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 22 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.
Protein: GB_ILTVS
Sequence: MQSYIAVNIDMASLKMLICVCVAILIPSTLSQDSHGIGWNNSPHDTASMDVGKISFSEAIGSGAPKEPQIRNRIFACSSPTGASVARLAQPRHCHRHADSTNMTEGIAVVFKQNIAPYVFNVTLYYKHITTVTTWALFSRPQITNEYVTRVPIDYHEIVRIDRSGECSSKATYHKNFMFFEAYDNDEAEKKLPLVPSLLRSTVSKAFHTTNFTKRHQTLGYRTSTSVDCVVEYLQARSVYPYDYFGMATGDTVEISPFYTKNTTGPRRHSVYRDYRFLEIANYQVRDLETGQIRPPKKRNFLTDEQFTIGWDAMEEKESVCTLSKWIEVPEAVRVSYKNSYHFSLKDMTMTFSSGKQPFNISRLHLAECVPTIASEAIDGIFARKYSSTHVRSGDIEYYLGSGGFLIAFQKLMSHGLAEMYLEEAQRQNHLPRGRERRQAAGRRTASLQSGPQGDRITTHSSATFAMLQFAYDKIQAHVNELIGNLLEAWCELQNRQLIVWHEMKKLNPNSLMTSLFGQPVSARLLGDIVAVSKCIEIPIENIRMQDSMRVPGDPTMCYTRPVLIFRYSSSPESQFSANSTENHNLGILGQLGEHNEILQGRNLIEPCMINHRRYFLLGENYLLYEDYTFVRQVNASEIEEVSTFINLNATILEDLDFVPVEVYTREELRDTGTLNYDDVVRYQNIYNKRFRDIDTVIRGDRGDAIFRAIADFFGNTLGEVGKALGTVVMTAAAAVISTVSGIASFLSNPFAALAIGIAVVVSIILGLLAFKYVMNLKSNPVQVLFPGAVPPAGTPPRPSRRYYKDEEEVEEDSDEDDRILATRVLKGLELLHKDEQKARRQKARFSAFAKNMRNLFRRKPRTKEDDYPLLEYPSWAEESEDE
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: U508_KLULA
Sequence: MDNTVRLDQLHDEQYRRILPTLNGYFEQKDTSLSRLDPRNYRNENYKKMNAIIPVLLRAHQCHPTDWKLLFANAQTLNFYSALLEGLLMFMFQSFSTTVGFGSNMEFLRCMLKTYEYLYTVAKTLPSPELGQRVMSFQNHFMRNWNKVQCESLLFDQVKDLLSHAHDFVAPPLFNLESVIKRDYFKITCDKLRYENLCVELFHLDNGNMAIFKVNTQTLPLYTNEQTHELLLRLTRNIDMGAYQDPLFQIGRTLLFPTIRPMDLRIADESRKSILLETKTGNGVTLALTPYDTLAWSQHWRPFVQSLCAVADSPKAFLSDRNESTFGSPINKDTITSAGTRGLGISLKKSEVRTNLDTGLRKSKPLASEALSISEIESLNMKKLMELNDSTDASTMNSSMKSPVPTNIRHIQEPSNIIEQMSPVIGSRVDDIDSIISDDDGINNEGSLGGSPVFNLSAEFHKPQLTKRKSSSFLNLFKKDKSKSQKNSTDSLAKLSDTKSIHPPESAMSSHASTPSSTSKSSKSSKSSSTLSPSTCKLPSSVKLDTNNVLLDTLVKLSQWRNNSWRFFSSSWLQLQVVNSNQGRYMFVVQDDNSNLKLCIAIGERWTISRTTAQDIQIRFPPTDVVASVAEPVPTLLSVRCPQVDNIANLLKHCKKNEVILTSSNNMSNSATQLTLGSNSSSILSNNVSNMSFSRSSTASNDLSHGWSKPQVLDSSKDCKSLLLLSKIKVRLHKYDQQYGWKMTKVGLLNVYSREYNGSVAGCKFEMDDTESFISSISDLKRIGRTGISAGERLVEFKNQNVADETYKLLGAL
What are the official names of this protein?
UPF0508 protein KLLA0A06237g.
What is the protein family that this protein belongs to?
Belongs to the UPF0508 family.
Protein: SERA_DICDI
Sequence: MDPTTSFPKDKIKILLLENIHIAAIKQFEEQGFQVESISSSLPEDKIIEKIKDVHVLGLRSKTKVTEKILSEAKRLLAIGCFCIGTDQVDLIEAEKRGVPVFNSPFCNSRSVAELIICEIITLSRKLGDRSTEMHNKIWRKESANCHEIRGKTLGIIGYGHIGSQLSVLAEAMGMSVLYYDIARRLPLGNSKMCPDMKTLLENSNFVTLHVPDTKETVGLIGEEEINTMKKGSYLLNASRGKVVQIPHLANALRSGHLAGAAVDVYPEEPSANCKDWECELQKCPNTILTPHIGGSTEEAQEAIGLEVSDLIVQFINSGASAGSVNFPEIALPVSPSTHRILNIHNNKPGVLRDINNILSEFNVSAQVLSTRKQIGYIIADVDSEASKEIKKKISSLPNSIKTRVLY
What is the function of this protein?
Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway.  Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
What are the official names of this protein?
D-3-phosphoglycerate dehydrogenase, 3-PGDH, 2-oxoglutarate reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: BIOH_ECO5E
Sequence: MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLAEMAEAVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRLPLQNVPMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFISHPVEFRHVLVALKQRV
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_LIGS1
Sequence: MVKKRIYELAKELGISSERVIEIAKKYDFKVTNHMSALDENEQNKIRGSISLKAKKKEHIQHNKNKDNFHSKKVQKSNTGSKDENNHKNVHKNNRKRSGSSMKENNNAKNGQRNNRNNRSNNKFKNKRNNNNKRNNNFKKGNPVPPRKNKPLPETLVYTVGMNVADIAKKIHREPAEIIKKLFMMGVMVNQNQSLDKDTIELLAADYGINAEEKVEVDVSDIDKFFEEEQNNTEHLEKRPPVVTIMGHVDHGKTTLLDKLRHTHVTEGEAGGITQHIGAYQVRHDDKIITFLDTPGHAAFTNMRARGADITDITVLVVAADDGVMPQTIEAINHAKAAGVPIIVAVNKIDKPGANPNHVMEQLTEYELIPESWGGDTIFVEISAKFGKNLDELLDMILLEAEMLELHANPNQRGAGSVIEARLDKGKGSVASLLVQQGTLHVGDPIVVGNTFGRVRTMVDARGYDIKKATPATPVEITGLNEVPDSGDRFITFEDEKTARAAGEKRAERALLKERSQTNHVTLDNLFDTLKEGELKEVGVIIKADVQGSVEALAQSFKKIDVEGVRVNIIHQAVGAINESDVTLAEASNAIIVGFNVRPTPLAKQQAESDNVDIRLHRVIYKAIDEIETAMKGMLEPEYQEKITGQVEIRQTYKVSKLGTIGGGYVIDGYIRRDSGVRVIRDGIVIYEGKLASLKRFKDDVKEVKQGYECGLMIEKYNDIKVGDQIEAYIMEEVPVD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_THEMA
Sequence: MRMKDLYAPTLKETPSDVETVSHEYLLRGGFIRKVAAGIYTYLPLGRRVLLKIENIVREEMNRIGAQEILMPILQPAELWKQSGRWDDYGPEMMKLKDRHERDFTLGPTHEEIVTDLVKNELRSYKQLPLTLYQIANKYRDEIRPRFGLLRAREFIMKDAYSFHASWESLDETYEQFKKAYSRIMERLGVRYMIIEAETGAIGGNASHEFVVPAKIGETNVLFCEKCGYQASDEKAEYKGEYTQEQEEEKPLKKVPTPGVKTIEEVSEFLGVPPSKIVKSLLYKGREGYVMVLIRGDLELNEAKLKAHLKDQSLRMATPEEILKDFGVPVGFIGPIGVDVKKVADHSVRGLKNFVVGGMEEDTHYVNANHPRDFKVDEWYDLRTVVEGDPCPVCGEPLKATKGIELGHIFKLGTKYSEAMKAYFMDENGEMKPFIMGCYGWGVSRTMAAVVEHFHDENGMIWPLSIAPYTVVVDILNMNDAEQKQVGEKIYQVLSEKGEEVVLDDREVSPGFKFKDADLIGFPIRINVGRSLKEGVVELKKRYSKELVKVNIKNGFGALLETLEKMKREYDPKEAVR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIT_ARTBC
Sequence: MSGPALKVAITQAQPKWLDLAGSVEKTVNLIAEAAKGDARLVAFPECWIPGYPGWIWQRPVDPIINTKYIQNSLSVNSAEMNTIKSAAKENNIAVVLGFVEAIDTHSVYIAQAIISPKGELLMHRRKIKPTHMERTVFGDGSGSDLTNVADVDFGGDIGVVKVGTLACWEHALPLLKYHTYSQKEAIHIAMWPPIDPHPGVDAPALWSMSAEGCQNLSQTHAIEGGAYVLHCTAVCNEEGIEGMKTKGGLLFQEPGGGHSAAIAPDGRRLTKPLADGNPAAEGIVYADLDMARVVMNKGFIDVVGHYSRPDLLWLGVDKAQKGCVVPKREPEQDV
What is the function of this protein?
Nitrilase that hydrolyzes preferentially phenylacetonitrile, (R,S)-mandelonitrile, and 3-indolylacetonitrile.
What are the official names of this protein?
Arylacetonitrilase, NitAb.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: GLGL3_ORYSJ
Sequence: MQFSSVFPLEGKACVSPIRRGGEGSASDRLKIGDSSSIKHDRAVRRMCLGYRGTKNGAQCVLTSDAGPDTLHVRTSFRRNFADPNEVAAVILGGGTGTQLFPLTSTRATPAVPIGGCYRLIDIPMSNCFNSGINKIFIMTQFNSASLNRHIHRTYLGGGINFTDGSVEVLAATQMPGEAAGWFQGTADAVRKFIWVLEDYYKHKAIEHILILSGDQLYRMDYMELVQKHVDDNADITLSCAPVGESRASDYGLVKFDSSGRVIQFSEKPKGTDLEAMKVDTSFLNFAIDDPTKFPYIASMGVYVFKRDVLLNLLKSRYAELHDFGSEILPRALHEHNVQAYVFADYWEDIGTIRSFFDANMALCEQPPKFEFYDPKTPFFTSPRYLPPTKSDKCRIKDAIISHGCFLRECTIEHSIVGVRSRLNSACELKNTMMMGADLYETEDEISRLLSEGKVPIGVGENTKINNCIIDMNARVGRNVVITNSEGVQESDRPEEGYYIRSGIVVILKNATIKDGKVI
What is the function of this protein?
Involved in synthesis of starch.  Catalyzes the synthesis of ADP-glucose, a molecule that serves as an activated glycosyl donor for alpha-1,4-glucan synthesis.  Essential for starch synthesis in leaf chloroplasts.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase large subunit 3, chloroplastic/amyloplastic, OsAGPL3, OsAPL3, ADP-glucose pyrophosphorylase AGPL3, ADP-glucose synthase AGPL3.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CSRP1_BOVIN
Sequence: MPNWGGGKKCGVCQKTVYFAEEVQCEGSSFHKSCFLCLVCKKNLDSTTVAVHGEEIYCKSCYGKKYGPKGYGYGQGAGTLSMDKGESLGIRHEEAPGHRPTTNPNTSKFAQKVGGSERCPRCSQAVYAAEKVIGAGKSWHKSCFRCAKCGKGLESTTLADKDGEIYCKGCYAKNFGPKGFGFGQGAGALVHSE
What is the function of this protein?
Could play a role in neuronal development.
What are the official names of this protein?
Cysteine and glycine-rich protein 1, Cysteine-rich protein 1, CRP1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSI12_STRHY
Sequence: SLYPASALVLTVGHGADAATAEVQRAVTLSCRPTPTGTHPAPAQACAELHSVGGALGLLRTGAEPGRMCTKEWRPITVTAEGVWDGRRVSYEHTFANNCFKNAAPTTVFEF
What is the function of this protein?
Strong inhibitory activity toward subtilisin BPN' and, to a lesser extent, toward trypsin.
What are the official names of this protein?
Subtilisin inhibitor-like protein 12, SIL-12, SIL12.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I16 (SSI) family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROB_ECO5E
Sequence: MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGTFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQA_PSEPF
Sequence: MAWTKPAYTDLRIGFEVTMYFASR
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.
Protein: Y4774_PSEA8
Sequence: MPSFDVVSELDKHELTNAVDNAIKELDRRFDLKGKCSFEAKDKSVTLTAEADFMLEQMLDILRSNLVKRKVDSQCMEIKDAYPSGKVVKQDVNFREGIDKDLAKKIVGLIKERKLKVQAAIQGEQVRVTGKKRDDLQEAIALLRGESLGMPLQFTNFRD
What are the official names of this protein?
UPF0234 protein PLES_47741.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: PSBK_PROM0
Sequence: MLILFNTFAELPEAYKAFAPTVDVLPLIPLFFFLLVFVWQAAVGFK
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: NU2M_HYACU
Sequence: MLYLLLTTTLLMMTWNRYAGRIAFLSLLGYFVIMLNIWLHFGSLSESVTLLFGGGLVRLDESILSALLFILFLGLVIMNRTGDLGWEFHLLLMGGLTGAIYMLTAYDLLLMVVGFEFLNLSTYLILSLYRGTETATLKYLLSSAFYTTLLLLAISFFYGLTGSTGYDALFVQMNYLGGETFLPQILLLGTIAFKLGLVPAHLWVPDVYDGLPMTLLSWMGSVPKAAVLLWLPTIYPLLNQLAPFLLVLSALSFLLSAVLMAAQYKMKRFLAYSAIGHLGFVVAAFAIGDYHAYGYYIFIYMIATLAQFVLLSELPQTELMKQTSVLKDHRALGLGFLVIVLTMASLPPFAGFYAKLLVLFGFLEIGYGIFAVLLILASLRSAAYYLKWIQTTFFSVVPFASAPIQVQYPNLVSFLVTLILPSTLLLLL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLMM_ALIB4
Sequence: MKLFGTDGVRGKAGDFLDAITVLKLAKAAGIYFRKHSTTNKILVGKDTRRSGYMIENALVSGLTAVGYDVIQIGPMPTPAIAYLTESMRCDAGIMISASHNPFEDNGIKFFDNHGNKLNTTCEEEIENIFNDMDLMQSEQVTGRDIGSSKRIDDVIGRYIVAIKSSFPKNLTLKGLRIILDCANGAAYKVGPTILEELGADVITINNKPNGFNINENCGAMHPETVSNLVKEYRADIGLALDGDADRLVVIDEKGEIVDGDNLLGALSVYLKNENLLKGDACVATVMSNKALEDYLQKNKISLFRSNVGDKYVLEVMKEKGINFGGEQSGHIIFSDIAKTGDGLASALQVLALIIKSGKKASEILNPFSLYPQILHNMKVTEKIPLEQITGLEEVLKPIRQKGLRDLIRYSGTENKIRLLLEGKNKKDVEDAMQTLIAFFKKAL
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: FOLD_SHEB5
Sequence: MTAQIIDGKAIAQSIRTKLSEKVTARKEAGQRIPGLAVVLVGADPASQVYVGSKRKACEEVGFISRSYDLETSCSEDELLSLIDSLNDDPTIDGILVQLPLPAHIEDSKVIERIRPDKDVDGFHPYNVGRLAQRIPVLRSCTPMGIMTLIKSTGVDTYGLDAVVVGASNIVGRPMTLELLLAGCTTTTCHRFTKNLEQKIRIADLVVVAVGKPGFIPGEWIKPGAIVIDVGINRLDNGTLVGDVQYDVAAQNASFITPVPGGVGPMTIASLLENTLYAAEQYHD
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: QUEF_CUPPJ
Sequence: MSLPEHSPLGKPSAYKTEYDATLLFPIARQPKRTEIGLPAGKPVPFFGVDIWNAYEVSWLNMRGKPQVALATFIIPSDTPNIIESKSFKLYLNSFNQTKIASPEALQQLLHHDLSEATGGTVQVRLVTEADLGKQKMGELEGLLLDRLDIEVDRYEPAPDLLKADQQESPVEETLVSHLLKSNCLVTGQPDWGSVQIRYVGAPINQEGLLKYLISFRNHNEFHEQCVERIFMDVMRECKPVKLAVYARYTRRGGLDINPFRTNFNTPWPDNLRNARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_STAAS
Sequence: MEARDILKRPVITEKSSEAMAEDKYTFDVDTRVNKTQVKMAVEEIFNVKVASVNIMNYKPKKKRMGRYQGYTNKRRKAIVTLKEGSIDLFN
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: UPPP_LEPIC
Sequence: MNPYLNAFLRSIIEAITEFLPVSSTGHLFLFSSFFPFYGENVEFDDLFDIFIQSGAILSVLFLYREKFKSQIVSSFRYILKQNSDSEGFHFLIQICIGAFPILIAGFIAKKFLDTIKARPDLLEILSGAWIFGGVLILVAEWYFHQRPEEKKSIGFKDSILIGIFQCMALIPGMSRSAATIITARFLGKDTKSSAEFSFFLAVPVLLAAGIYKLIKYRSILNGNTIPVLMFGFLVSFLLCTLVIRWFLRYIQKHSFSVFGVYRILLGVGVLVLTKLI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.