PharMolix/UniProtQA huggingface dataset:
Protein: RIMO_BRUAB
Sequence: MSAPRVSFVSLGCPKALVDSERIITGLRSEGYEISRKHDGADLVIVNTCGFLDSARDESLEAIGLALNENGKVIVTGCLGAEPDVIRERHPNVLAITGPQAYESVMNAVHEVAPPAHDPFVDLVPPQGVKLTPRHYAYLKISEGCSNRCSFCIIPALRGDLVSRPINEVLREAEKLVQAGVKEILVISQDTSAYGLDIKYQEAMWQDRTVRTKFLDLSRELGEMGVWVRMHYVYPYPHVDEVIPLMAEGKILPYLDIPFQHASPAVLKNMRRPAHQEKTSRRIQAWRETCPDLAVRSTFIVGYPGETEEDFQMLLDWLDEAKIERAGCFKYEAVKGAKANDLGLEQVPEEVKEARWHRFMAKQQQISTNLLKKKVGKRLPVIIDEANGTIGKGRTRYDAPEIDGSVHISSRRPLRVGDIVTVKIEASDAYDLHGTAV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_PSEAB
Sequence: MAHKKAGGSTRNGRDSESKRLGVKLFGGQAVKAGNILVRQRGTKFHAGYGVGLGKDHTLFAKVDGVVKFETKGAFGRKYVSIVAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: IL4_HUMAN
Sequence: MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS
What is the function of this protein?
Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses (PubMed:3016727, PubMed:1993171).  Induces the expression of class II MHC molecules on resting B-cells.  Enhances both secretion and cell surface expression of IgE and IgG1 (PubMed:1993171).  Regulates also the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes (PubMed:2521231).  Positively regulates IL31RA expression in macrophages.  Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.  In addition, plays a critical role in higher functions of the normal brain, such as memory and learning (By similarity).  Upon binding to IL4, IL4R receptor dimerizes either with the common IL2R gamma chain/IL2RG to produce the type 1 signaling complex, located mainly on hematopoietic cells, or with the IL13RA1 to produce the type 2 complex, which is expressed also on nonhematopoietic cells (PubMed:10219247, PubMed:11526337, PubMed:18243101).  Engagement of both types of receptors initiates JAK3 and to a lower extend JAK1 phosphorylation leading to activation of the signal transducer and activator of transcription 6/STAT6 (PubMed:7721895).
What are the official names of this protein?
Interleukin-4, IL-4, B-cell stimulatory factor 1, BSF-1, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL27_RHOE4
Sequence: MAHKKGASSSRNGRDSNAQRLGVKRFGGQSVSAGEILVRQRGTHFHPGVNVGRGGDDTLFALAAGAVEFGQKRGRKTVNIVPAVVAAEV
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: VATB_ANADF
Sequence: MDLVTRRVRGADAIAGPLLFLEGVPRARLGELVRIRMAGGEERRGQIIELSGARVAVQVLEETRGLAPARAEVTLTGEVATLAVSRGMLGRVLDGLGRPTDGLPAPIAEARLPIHGAALNVTRREKPADFIETGVSAIDGLNTLVRGQKLPVFSCAGLPAGRLAGQIVCQARVRGGERFAVVFAAMGAPFREYDAYLEAFRRAGVLDRTAVFLNRAEDPPIERLMTPRCALTCAEHLAFSHGLHVLVVLTDMTSYCEALREVALARDEVPGRRGYPGYMYTDLATIYERAGRIAGRPGSITQVPVLTMPDDDLTHPIPDLSGYITEGQIVLSRELDRRGVYPPIDVLPSLSRLMGLGAGPGRTRADHRPLADQLYALYARGRDVRRMAAIVGSANLGEEERRLLEFGDRFERELVGQGDAFRSIEDTLETGWRLLAQLPPEALARIPAAVLEARRKEGQR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: ARFT_ORYSJ
Sequence: MAQPPDAAAAAAVPPPVVIDRDVWHACAVPYSGVLPGVGTLVYYIPHGHIEQCAEDPALLLSRLPDPIHPVPCTVADLVLDVDAESGEAYATISLLPGSHDDTTARRQVPAHGEPGFRFFEKQLSPADVTSNALVLPAGAEHVLPPLDIAAYQTARLFDVRDLRGKRFEFVHIWDKKRCRYMLGDLGVNDNDGWRGFVKAKRLATRDTVVFMRRGGGDGDGDGELLVGVRRAPRARGGHHPRPGVEDNKVVSEVWLAMQGVTPFEVTYYPREGTFEFVVSRDEYIGFSFSPFYPFVPGTTVHLRMNPLQIAQSISGTVRTFDHLRPWRMLEVDWDQAASPISYRIHRQVNSWQVLRQPQPAATTSAVRIRDAIVATPQVQIMALPRPPPPTTTTGMVPSDDSYAMISLFPGDCYVTHRPLPAARDPVGGQREFCFFDKKLSPSDAAANGGGSGALFVIPKPSAAEHVLPRIPDLRVTNLQGGRWEFGHTWSDADTDRRSSSHTLAAGWSAFVKAKRLCVGDTVIFMRRRPGGEPLVGVRRKPHGGMPVGIPDKHVADAWLDASSAQPFRVTYCPWQGTAEFVVRREEVEGSPPLAPGTRVRLLMNPDDARRRSQPPVYGTVRDVHCRSEWRMLEVDWDRDSPLAPTMNRRVNSWQVQPVQLALPPQGSDEEAAAATTSTAHAGDATTSAPSLALQLQTMASSSSSSAPIIPSRGSAFRIVNPRDGSQG
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
What are the official names of this protein?
Putative auxin response factor 20.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGLR1_ARATH
Sequence: MANARSLVAKANNINVGSLILMALVFGSCVANGEYLGGRRGLAANSGNPTVYDITKFGAVGDGSTNTFKAFLNTWIQVCDSPVPATLLVPKGTFLAGPVIFAGPCKSKVTVNVIGTIIATTSGYATPEWFLFERVDNLVLTGTGTFHGKGEAVWKADGCGKKVQCNLPPTSLKFRNMKNVEINGISSVNAKAFHMFLVKTENVNIQNIKLTAPAESPNTDGIHLSNADNVSILDSTIATGDDCVSVGRGSNNVTVERVICGPGHGLSVGSLGKYKNEEDVSGIHVNNCTMIETDNGLRIKTWGGSDPSKAVDIKFENIIMQSVKNPIIIDQNYGSRGGDSQVAISDILFKNIRGTTITKDVVQIMCSKSVPCQGVNVVDVNLDYVGKTGGEKKSSSGGLVGALCDNANVIFGGKLSFPMCPK
What is the function of this protein?
May function in depolymerizing pectin during pollen development, germination, and tube growth.  Acts as an exo-polygalacturonase.
What are the official names of this protein?
Exopolygalacturonase clone GBGE184, ExoPG, Galacturan 1,4-alpha-galacturonidase, Pectinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: YMEL1_HUMAN
Sequence: MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFSDFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRDLGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSCLYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFLLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR
What is the function of this protein?
ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region (PubMed:26923599, PubMed:27786171).  Plays an important role in regulating mitochondrial morphology and function by cleaving OPA1 at position S2, giving rise to a form of OPA1 that promotes maintenance of normal mitochondrial structure and mitochondrial protein metabolism (PubMed:18076378, PubMed:26923599, PubMed:27495975).  Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins (PubMed:22262461).  Required for normal, constitutive degradation of PRELID1 (PubMed:27495975).  Catalyzes the degradation of OMA1 in response to membrane depolarization (PubMed:26923599).  Required to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1) (PubMed:22262461).
What are the official names of this protein?
ATP-dependent zinc metalloprotease YME1L1, ATP-dependent metalloprotease FtsH1, Meg-4, Presenilin-associated metalloprotease, PAMP, YME1-like protein 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
Protein: MT1_WHEAT
Sequence: MSCNCGSGCSCGSDCKCGKMYPDLTEQGSAAAQVAAVVVLGVAPENKAGQFEVAAGQSGEGCSCGDNCKCNPCNC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein 1, MT-1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: Y020_PROMA
Sequence: MAGFGLPNFGQITEAFKKAQQIQQDAQKLQEELDDMELEGTNEDGRVTVWLSGNQQPIRVKVENSILKEEEEIVEAAILEAMQKAHEISTSNMKSRMQELTGGLNLNLPGINDDN
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Pro_0020.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YQGE_SALPC
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNQDGAMGIIVNKPLENLQIEGILEKLKITPEPRDSAIRLDKAVMLGGPLAEDRGFILHTPPSRFASSIRISDNTVITTSRDVLETLGTQQQPSDVLVALGYASWDKGQLEQELLDNAWLTAPADLNILFKTPIAERWREAAKLIGIDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RL13_MICLC
Sequence: MRTYSPKPGDADRQWHIIDATDVVLGRLASHTATLLRGKHKPTFAPHMDMGDYVIIVNAEKVALTGAKLEKKRAYRHSGYPGGLKSQSYAELLETNPVRAVEKAVKGMLPKNSLAAQQLSKLKVYKGAEHPHTAQQPQTFEIGQVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: METAA_DINSH
Sequence: MPIKIPETLPAFDVLSSEGVMVMGQGRADRQDIRPLQIGLLNLMPKKIQTETQFARLIGATPLQIDLTLIRMTEHQSKHTSAAHMEAFYRPFAEVRDRKFDGLIITGAPIEHLEFADVTYWDELREVFAWTQTNVHATFGVCWGGMAMINHFHGVQKHILPAKAFGCFRHRNLAPASPYLRGFSDDCVIPVSRWTEMKQSEIDAVPGLTTLLGSPEVGPCLVEDPGHRALYIFNHFEYDTGTLKEEYDRDVENGTPINVPTNYYPDDDPARAPLNRWRSHAHLLYGNWLNEIYQTTEYDLEKIGT
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_STRP8
Sequence: MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLMNKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTNVSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDRLSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVAVVTQEIIASAGGAGSKFGTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVTHD
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_NANEQ
Sequence: MVDRKGKGFRRKTRDKLSKHPRQRGKLTITRILQKFNNNDKVAIVIEPSWHYGMPHPRYHGLVGTVVGKRGNCYEVELEFNGEKKLLIVHPAHLKKVG
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: MTNA_AJECN
Sequence: MTLVAITYTRGSLHILNQLLLPHQTTYDPLHSARDAWHAIHEMRVRGAPAIAIVAALSLAVELHTLATSNQLSAEPKDVGQLILEKLEFLVSSRPTAVNLAEAAGRLGRIVNGRAQVQGVGGNEVAEAYIEAAERMLDDDVRDNRAIGESGAKWVLEHAITKGSISGTGQAKVAVLTHCNTGSLATAGYGTALGVIRSLHATGSLERAYCTETRPYNQGSRLTAFELVHDNIPATLITDSMAAALLARQSAGPAQSVGVSAIIVGADRVAANGDTANKIGTYGLAVLAKYHGVKFLVAAPRTTIDMNTKTGADIVIEERPEKEVTRIRGPRDGEEGNGLGAMETITVAADGIGVWNPAFDVTPAALVDGIITEVGVVEKDGSGVFHLERIF
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1485_STAAC
Sequence: MVKTVYVTGYKSFELNIFKDDAPEVHYLKQFIKHKIEQLLDEGLEWVLIQGQMGIELWTAEVVIELQRTYDSLKFAVITPFQGHTEKWNEHNQSKYANIIKHADYVDSIFHTSYQGPFQFKQADQFMLEHSDQTLLIYDEEQEASPKFFKQMLVDFMDKTNYTCDIVTFDELTAFINDLQWSEDQSF
What are the official names of this protein?
UPF0398 protein SACOL1485.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: ADC_BURCH
Sequence: MKPSDVRSKAFAMPLTSPAFPMGPYRFVDREFLIITYRTDPDRLREIVPEPLQVTEPLVHYEFIRMADSTGFGDYTESGQVIPVEYEGQPGGYTLAMYLDDHPPIAGGRELWGFPKKLASPTLHVNTDHILGTLDYGKVRVATGTMGYKHKELDIDEQTKRLAGPNFLLKIIPHVDGTARVCELVRYYMQDIKMKGAWTGPASLELAPHALAPVADLPVLEIVEARHLVADLTLGLGEVVYDYLAQ
What is the function of this protein?
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.
What are the official names of this protein?
Acetoacetate decarboxylase, AAD, ADC.
What is the protein family that this protein belongs to?
Belongs to the ADC family.
Protein: E3B14_ADE12
Sequence: MKTALVLFFMLIPVWASSCQLHKPWNFLDCYTKETNYIGWVYGIMSGLVFVSSVVSLQLYARLNFSWNKYTDDLPEYPNPQDDLPLNIVFPEPPRPPSVVSYFKFTGEDD
What is the function of this protein?
Down-regulates the EGF receptor and prevents cytolysis by TNF.
What are the official names of this protein?
Early E3B 12.7 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3_14 family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: RL14_STRPC
Sequence: MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NCAP_NIPAV
Sequence: MSDIFEEAASFRSYQSKLGRDGRASAATATLTTKIRIFVPATNSPELRWELTLFALDVIRSPSAAESMKVGAAFTLISMYSERPGALIRSLLNDPDIEAVIIDVGSMVNGIPVMERRGDKAQEEMEGLMRILKTARDSSKGKTPFVDSRAYGLRITDMSTLVSAVITIEAQIWILIAKAVTAPDTAEESETRRWAKYVQQKRVNPFFALTQQWLTEMRNLLSQSLSVRKFMVEILIEVKKGGSAKGRAVEIISDIGNYVEETGMAGFFATIRFGLETRYPALALNEFQSDLNTIKSLMLLYREIGPRAPYMVLLEESIQTKFAPGGYPLLWSFAMGVATTIDRSMGALNINRGYLEPMYFRLGQKSARHHAGGIDQNMANRLGLSSDQVAELAAAVQETSAGRQESNVQAREAKFAAGGVLIGGSDQDIDEGEEPIEQSGRQSVTFKREMSISSLANSVPSSSVSTSGGTRLTNSLLNLRSRLAAKAAKEAASSNATDDPAISNRTQGESEKKNNQDLKPAQNDLDFVRADV
What is the function of this protein?
Encapsidates the genome protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication (By similarity).
What are the official names of this protein?
Nucleoprotein, Protein N, Nucleocapsid protein.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: CTNS_BOVIN
Sequence: MIRRWLVIFILFPLQLIEKCESTVDFSVPPIVKLEKGSSTSVSISLPRPLNATLVITFEITFRSKNVTILQLPDEVVVPPGTTNSSFRVTSQSVGQVTTYLHGNHSNQTSPRIRFLVIHSNIVSIINQVIGWIYFVAWSVSFYPQVITNWRRKSVVGLSFDFVVLNLMGFVAYSVFNIGLFWVPSIKEQFLLKYPNGVNPVDSNDVFFSLHAVALTLVVIVQCLLYERGSQRVSWLAISFLVLSWLFTLIALIMAAVGATTWLQFLFCFSYIKLAVTLVKYFPQAYMNFHYKSTEGWSIGNVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGLGIFSIIFDVVFFIQHFCLYRKKPGYDQLN
What is the function of this protein?
Cystine/H(+) symporter that mediates export of cystine, the oxidized dimer of cysteine, from lysosomes.  Plays an important role in melanin synthesis by catalyzing cystine export from melanosomes, possibly by inhibiting pheomelanin synthesis.  In addition to cystine export, also acts as a positive regulator of mTORC1 signaling in kidney proximal tubular cells, via interactions with components of the v-ATPase and Ragulator complexes.  Also involved in small GTPase-regulated vesicle trafficking and lysosomal localization of LAMP2A, independently of cystine transporter activity.
What are the official names of this protein?
Cystinosin.
What is the protein family that this protein belongs to?
Belongs to the cystinosin family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Melanosome membrane; Multi-pass membrane protein. Note=AP-3 complex is required for localization to the lysosome.
Protein: INVC_ARATH
Sequence: MNSRSCICVSAMKPCCRFLISFRSSSLFGFSPPNSGKFINSSKLHCTKIDSRSIRSGIHCRRIVLDRNAFCDSDSISWGGGGSRVLRARGSSRGRGRGVLVIPHVASDFRNYSTSSLDSHVNDKSFESMFVKPLVFKEVEKTEGIPKRERGNVGGGKDANFGNVGVRKETERCLSQTEVEKEAWKLLRGAVVNYCGFPVGTVAANDPGDTQTLNYDQVFIRDFVPSAYAFMLDGEGEIVRNFLLHTLQLQSWEKTVDCHSPGPGLMPASFKVKSAPLEGNDGSFEEFLDPDFGGSAIGRVSPVDSGLWWIILLRAYGKLTGDYTLQERIDVQTGIKLILKLCLADGFDMFPTLLVTDGSCMVDRRMGIHGHPLEIQALFYSALRCAREMLIVNDGTKSLVTAVNNRLSALSFHIREYYWVDIKKINEIYRYNTEEYSADATNKFNIYPEQIPTWLVDWIPDKGGYFIGNLQPAHMDFRFFTLGNLWAVISSLGNQEQNEGVMTLIEEKWDDLVANMPLKICFPALEKDEWRIITGSDPKNTPWSYHNGGSWPTLLWQFTLACIKMGKLELAKKAVAVAEKRLKEDEWPEYYDTKSGRFVGKQSRLYQTWTIAGFLAAKKLIEQPEKASLLFWEEDYQLLETCVCGLSKSSGRKNKCSRFTPPRS
What is the function of this protein?
Mitochondrial invertase that cleaves sucrose into glucose and fructose and is involved in the regulation of aerial tissue development and floral transition.  May be modulating hormone balance in relation to the radicle emergence.
What are the official names of this protein?
Alkaline/neutral invertase C, mitochondrial, A/N-INVC.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 100 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RUVC_FRASN
Sequence: MRVLGVDPGLTRCGLGVVDGGPGRRASLVEVGVVRTPASDEVADRLRAVSEGVDEWLDRVRPDAVAVEKVFSQANVRTVMGTAQAGAVAIVAAARRGLPIGLYTPSEVKAAVTGSGRADKAQVGFMVTKLLDLPEAPRPADAADALALALCHLWRGPALARMRAATPARSPGVPGGRR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ATPF_CAMHC
Sequence: MNKFLFFIFVFVGISFAGDDTATKDYDIVWRTINFAIFFGILFYLIKGPIKNAYNARINRISSRLEAIQTKLKESKEKKEASKKNLEDVKQKCVELIETAKKEAIQLDEKIQQSAQIDIAQMQKSFAEQKEFEIRRLKKSVTAEILDELFNEKSVNLSQNELINLVQKKVV
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ASTD_ACIAD
Sequence: MSHANLWIDGNWVQGQGKSWNTCNPVSQQVVWQGNEATAQQVEQACEAARQAFPQWATTSLTDRIAIIERFALLLEQNKEALAKIISQETSKPLWETLTEVQSMVAKVAISIRAYHQRTGKSITEMADGAASLRHRPHGVMAVFGPYNFPGHLPNGHIVPALIAGNVVVFKPSELTPWTAEATVKLWQQAGLPNAVLNLLQGSRETGIALAQSEHIDGVLFTGSASTGYQLHRQLAGAPEKILALEMGGNNALIIEDIDDIDAVVHLAIQSAFISAGQRCTCARRLIIKNGQAGDAFIQRFIEVARDLVIGDWDAEPQPFMGGVISVKAAEALLKAQQNLIDLGARSLLEMKQLRENSALVSPAILDVTAVPDIPDEEYFGPLTCIYRYDDFDEALKLANSTRFGLSVGLVSPKRALFERMLIEARAGIVNWNKPLTGASSAAPFGGVGASGNHRASAFYAADYCAWPMASLESEQLSLPEKLSPGIVL
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: PDXS_SULIL
Sequence: MRLYELSFAQIEDFFYKLAEVKDIIKDSGLMEFLPELKKLDSTIQTGTTRVKHAFPIFQKGGVVMDITNVQQAQIAEEAGAVAVMVLDKLPYDVRKSGGVARMADPKIIGEVMNSITIPVMAKVRIGHYYEAKLLEALGVDMIDESEVLTPADEEHHINKWEFSVPFVNGARNLGEALRRTAEGASMIRTKGEAGTGNVSEAVKHMKIINSEIRSLISMSEEDRVKKAREYQVPYQLVELTAKIKRLPIVNFAAGGIATPADAALMMWLGADGLFVGSGIFKSQDPDERAKAVVLAAACWEYPEIVLEAQKMISEQKSMMGIDIKSLKPEELLQVRGL
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: GET2_CANGA
Sequence: MSLSEAEKRKILRERRQQKFSRGGASERLNKIVGGQGSQLDTKSALDEKPEVVEEIPREAVKPEMNSSVQAKKESTAQAKAEDPQVELFRQLAEMQGQGATESTPDLFSMMKNLGATGDSPFPMAEQQVEAIDPELVEYHKYRVNTLTAKTTLVKWIVLLAYIFLLTRTDDTYFPFVVRSYLPEVFTSQSSFFSIFLTFEILATSIYYQLSVGVERETGVKTLQDTSKIVSLVSMVPEGILPIADLRGKVILAMKYWNIIAMMIGDVCFVLVAIGLVSQI
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 2.
What is the protein family that this protein belongs to?
Belongs to the GET2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.