PharMolix/UniProtQA huggingface dataset:
Protein: ALR_COXBU
Sequence: MNRATATINVTALKHNLSQIKALAPKSLAWAMIKSNGYGHGLVRVAKALSDANAFGVACIDEALTLREVGIKSPIIVMKGFYNEAELSQFARHRLGAVIHCSDQVSLLEKTNLTSSLSVWLKIDTGMNRLGFSVEQSPAVYNQLKTSSSIQKPIGLMTHLADADNENKTFTELQIKRFFSVTEKMIGPKSIVNSAGFFAYPNALVDWIRPGIILYGISPFGINYNSFKEKIEKKFRPVMTLSAKIIAIKNRRQNDSVGYGCTWSCPEDMPIAIVSIGYGDGYPRHAPSGTPVLLNGKICPLIGRVSMDMIAIDLRSQPNAQVGDDVILWGEGLPVEIIAEKAGTIAYELLCKITQRVQFIEIEK
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: RRF_STAAW
Sequence: MSDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYYGAPTPVQQLASINVPEARLLVISPYDKTSVADIEKAIIAANLGVNPTSDGEVIRIAVPALTEERRKERVKDVKKIGEEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQKATDNSIKEIDQMIADKEKDIMSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLB2_ASPFU
Sequence: MYKNRVELTTTAPVNRALPNAPDGYTPQGETCPSKRPSIRNATALSSAETSWLKARRNNTKDALKAFLSRVDLGSFNGSDYIANHSANASALPNIGIAVSGGGYRALMNGGGALQAFDNRTTNSTHSGQLGGILQSATYLSGLSGGSWLVGSIYMNNFSDVSSLQDNGSVWQFQDSIFSGPTQSTTWDIGTVEYYSQLLGAVDGKSNAGYEVSITDYWGRSLSYQLINASEGGVGYTWSSIALSKDFQAGTMPMPLVIADGRAPGEILVPANTTVFEFNPWEFGSWDKSLSAFVSLEFLGSNFSKGTLATGEKCVRGFDNAGFIMGTSSSLFNQAFLQMNNTDAPSVVKDAISAILGKIGSENNDIAVYKPNPFYRYASQSKYTSSPSLTLVDGGEDLQNIPLDPLLQPQRHVDVILAVDSSADTTTRWPNGTSLVATYERNVDSSQRNSSLPFPSVPDQNTFVNLGLNNRPTFFGCNSSNATGAPLVVYIPNAPYIYPSNVSTFDLQYNTSERNAIIENGYDVATLGNGTVDSNWPACLACAILSRSFERTNTTVPKTCSTCFKTYCWNGTINATTPGDYYPTLKLH
What is the function of this protein?
Catalyzes the release of fatty acids from lysophospholipids.
What are the official names of this protein?
Lysophospholipase 2, Phospholipase B 2.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
Protein: GALT1_DROME
Sequence: MLPRFRSFYGKLIIFILVALCFILYSKVQQNGSPEEPPVAPLVRAAALRGHGRERFEAYSDSENEIARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNEKPYNAGLYPCGKVLQKSQLFSFTNTNVLRNELSCATVQHSESPPYRVVMVPCMENDEFNEQWRYEHQHIIHSNTGMCLDHQGLKSLDDAQVAPCDPHSESQRWTIEH
What is the function of this protein?
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:12829714).  It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties.  Prefers the monoglycosylated Muc5AC-3 as substrate (PubMed:12829714).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 1, pp-GaNTase 1, Protein-UDP acetylgalactosaminyltransferase 1, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RUVB_CALS4
Sequence: MEERILTQNFTQEDATEYSLRPRWLSEYIGQEKIKQELKIYIEAAKKRGEPLDHVLLYGPPGLGKTTLATVISNEMGVGIKITSGPAIERSGDLAAILTNLQENDILFIDEIHRLNRSVEEILYPAMEDFELDIVIGKGPSARSIRLSLPKFTLIGATTRAALMTSPLRSRFGVINRLDYYSVEELKEIIKRSANILNIGIDEDAAFEIARRSRGTPRIANRLLKRVRDFAEVKGNGYIDYNTANIALNMLGVDEMGLEEIDRKILIAIIEKFGGGPVGIDAIAASVGEDGDTIEDMYEPYLMQIGFLNRTPRGRVVTKLAYQYLKYPYVEQRRIEDV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: THIC_SHIBS
Sequence: MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYLTGTHSGVRVPMREIQLSPTLIGGSKEQPQFEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: GLYA_ACTPJ
Sequence: MFTANMNIQDYDPILWQAIENENRRQEEHIELIASENYASPRVMQAQGSQFTNKYAEGYPGKRYYGGCEYADIVEQLAIDRAKQLFGADYVNVQPHSGSQANAAVYGALIQPNDTILGMDLAHGGHLTHGAKVSFSGKIYNSVLYGITAEGLIDYEDVRQKALECKPKMIVAGFSAYSQIVDWAKMREIADEVGAYLFVDMAHVAGLIAAGVYPSPLPYAHVVTTTTHKTLGGPRGGLILSACGDEEIYKKLQSSVFPANQGGPLVHIIAAKAVCFKEALEPEYKIYQQNVVKNAKAMVEVFKQRGYEVISNGTENHLFLVSFVKQGLTGKAADAALGQANITVNKNSVPNDPQKPFITSGIRIGTPAVTRRGFKEADVQALAGWMCDVLDSIGKDNHEQVIAETKAKVLDICARLPVYAK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_METPP
Sequence: MPEKKGSSSEKVLYCSFCGKSQHEVKKLIAGPSVFICDECIELCNDIIRDEVPAESGDAKAAKSDLPVPGEIKASLDQYVIGQEPAKRTLAVAVYNHYKRLKHVQGVGKKEDVELAKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVERAQRGIVYIDEIDKISRKADNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFLQIDTTNILFICGGAFDGLEKVIQNRSEKSGIGFGASVQSKTERKVSEVFREVEPEDLIKFGLIPELVGRLPVVATLGELTEDAMVQILTEPKNALVKQYQKLFAMDGVELEIRPSALTAIAQKALARKTGARGLRSIMEHSLMDTMFDLPTMDGVQKVVLDEHTIEEHTKPLLVYREQKASA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RPOA_XANAC
Sequence: MTVTANQVLRPRGPQIERLTDNRAKVVIEPLERGYGHTLGNALRRVLLSSIPGFAITEVEIDGVLHEYTTVEGLQEDVLDVLLNLKDVAIRMHSGDSATLSLSKQGPGTVTAADIRTDHNVEIINGDHVICHLTKDTALNMRLKIERGFGYQPAAARRRPDEETRTIGRLMLDASFSPVRRVAYAVEAARVEQRTDLDKLVIDIETNGTIDAEEAVRTAADILSDQLSVFGDFTHRDRGAAKPAASGVDPVLLRPIDDLELTVRSANCLKAESIYYIGDLIQKTEVELLKTPNLGKKSLTEIKEVLAQRGLALGMKLENWPPAGVAQHGMLG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RS5_ACISJ
Sequence: MAKFQPKVQSEGQDDGLREKMIAVNRVTKVVKGGRILGFAALTVVGDGDGRVGMGKGKSKEVPAAVQKAMEEARRNMVKVSLKNGTIHHNVTGHHGAAVVMMAPAPKGTGIIAGGPMRAVFEVMGITDIVAKSHGSSNPYNMVRATFDALTNSTTPAEVAAKRGKTVEDLFAA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: TSAD_BORRA
Sequence: MKVLGIESSCDDCCAAIVENGNTILSNIKLSQKEHKKYYGIVPEIASRLHTEFIMYVCQQAIISAKINISEIDLIAVTSQPGLIGSLIVGVNFAKGLSIALKKPLICIDHILGHLYAPLLNHTIEYPFLSLVLSGGHTILAKQNNFDDIEILGRTLDDACGEAFDKIAKHYKMGFPGGPNIEKLAIDGNQYAFNFPITIFDKKENRYDFSYSGLKTACIHQLEKFKNNNAQITNNNIAASFQRAAFENLIIPIKRAIKDTNIKKLIISGGVASNLYLREKIKNLEIETYYPPIDLCTDNAAMIAGIGYLMYLKYGASSIETNANSRIENYKYTKGVKL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_POLNA
Sequence: MDFELKTLTRTLICNEKADALIVLIPEGLTAGDDALSVLAALAIKSGDLEVKPGKLLNAYRVTGIAATRVLLVGAGDASPKSVRTAVNAAMGALKAGNNVQRAVLCLNALPTLQPEAVRAAIVACSETAYAYTTTKSKPAAAKLQQMVVAVDGLANAQAGFDKAVGLAKGIELAKEWANRPANHATPTLLAGAAKELGKLPRIKTEVLGPKEIEKLGMGAFLAVAQGTAEPLRFIVLRYEGAAKAEAPVVLIGKGITFDTGGISIKPAAEMDEMKFDMCGAASVLGTFRALAELQPGLNVVGLIPACENMPGDRAIKPGDVVTSMSGQTIEILNTDAEGRLVLCDALTYAARLKPRAVVDIATLTGACVVALGGVRSGLFSNNEALAESLARAGESSLDPCWRMPLDDDYAEGLKSNFADVANVAGRAGGAVTAAKFLQRFAADFAWAHLDIAGTAWKSGAAKGATGRPVALLLDFLLGQVQAVPAAQPVKASPKTRPARKSTPAAKTRA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMF_PSEFS
Sequence: MTAPSTPKPQRKKPKTATTAKPVVPRKEATLHPRNRHTGRYDFQALIKTTPELAQFVIINPYGKESIDFASPDAVRVFNRALLKSFYGIQHWDIPADYLCPPVPGRADYVHFLADLLASVNDGKIPRGSIVKVLDIGMGANCVYPLIGYMEYRWNFLGSEVDPIAVAAAKAIVQSNDLSKVIQLRQQTNPKQILLSLLEPGERFDLTMCNPPFHASMDEATKGSERKWRALGKADPKRKLPVLNFGGQSAELWCEGGEARFVTQLIAESAHFAHKVLWFSTLVSKASNLPAIETALKKAGVLESQVVEMSQGQKQSRFVAWTFQTKNEQQIWRQRWVRD
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGE_SHIDS
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: NHAP2_SHEON
Sequence: MDADSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNFALAIILLDGGMRTRVASFRVALWPALSLATFGVAITTSITGVMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGSNDPMAVFLTVTLIAILANVGAELSASFMLISFIKQFGLGVLLGLGGGWLLWKLVNVSKLAEGLYSILVLSGGLMIYATSNKLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLLDIWLPGLALAFGMILFARPLAVWLSLLPFKSFGSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVIVSLLVQGASLTTAARLAKVELPPKPLPISRSGVEIYPKSEWEVFVYCLSESKWCIGEPLKRLAMPDGTRIAAVFRNNTLLHPSGSTCLEAGDILCVLGQEKSLEALSNLFSQAPETDEVSRFFGDFFIDTEVKLADLAPIYGLTLDDETGAMTVADLVALELGAHPVLGDQFLWQSLHWVVAGLYEGKVTNVGIRLPADA
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TBP_THECE
Sequence: MSNVKLRIENIVASVDLFTQLNLERVIEMCPHSKYNPEEFPGIICRFDEPKVALLIFSSGKLVVTGAKSVEDIERAVNKLIQMLKKIGAKFSRAPQIDIQNMVFSGDIGMEFNLDAVALSLPNCEYEPEQFPGVIYRVKEPRAVILLFSSGKIVCSGAKSEHDAWEAVRKLLRELEKYDLIGEGEEEEW
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: NARJ_BACSU
Sequence: MNTTDRQITFSALSCLLSYPDEEWRAELPDWKALIQEIGNRQIREKLLHFFETSASYSPEALIEHYVYTFDFGKKTNMYVTYFNSGEQRERGIELLHLKNTYEQSGFLPTEKELPDYLPLMLEFAAAAEIEAARSVFEKYLSNVRELASRLEKNDSIYAELLHVLLAALENIGVRESVEGAVQA
What is the function of this protein?
Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase.
What are the official names of this protein?
Probable nitrate reductase molybdenum cofactor assembly chaperone NarJ.
What is the protein family that this protein belongs to?
Belongs to the NarJ/NarW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCPC_HELPJ
Sequence: MLENVKKSLFRVLCLGALCLGGLMAEQDPKELVGLGAKSYKEQDFTQAKKYFEKACDLKENSGCFNLGVLYYQGHGVEKNLKKAASFYSKACDLNYSNGCHLLGNLYYSGQGVSQNTNKALQYYSKACDLKYAEGCASLGGIYHDGKVVTRDFKKAVEYFTKACDLNDGDGCTILGSLYDAGRGTPKDLKKALASYDKACDLKDSPGCFNAGNMYHHGEGAAKNFKEALARYSKACELENGGGCFNLGAMQYNGEGATRNEKQAIENFKKGCKLGAKGACDILKQLKIKV
What is the function of this protein?
May hydrolyze 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
What are the official names of this protein?
Putative beta-lactamase HcpC, Cysteine-rich protein C.
What is the protein family that this protein belongs to?
Belongs to the hcp beta-lactamase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMA_BORAP
Sequence: MLLSLLSMNINYNSITSIKQTLKEKKIAPRKLWGQNYLINENIRQKIIESLDIKENEKIWEIGPGLGAMTDILLKKTNLLTAFEIDLKYSEILNEKFGKLKNFKLIKGDFLKKYPNENKNIDKIFSNLPYNIASKVISKLIEENFLKEMVFTVQKELADRITAKINSKNYSSFTVLVQSHFTVIKIIDIGGNNFYPAPKVKSTTLKLIPKKHNIKDFKEFNKLIRTVFSSRRKKLKNTIINFITNKAILRENFLKEYLDKRPENISVEEFIQISNTLTAYH
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASQI_EMENI
Sequence: MTCTLRDLNSLLEICCRCPAHNPSTAFAPTTKVRVSSDVRGIFALPVQKDHKPYNGLSPEHLETMKAVSLMLDAAGPKLEDGISKAKELLEERINPELMRDALGIYLTHSKDAQQRKIFPPPLKNHPFFSTKTRRPANVAGEICTADTLHGHALLSYWRDDYDLNDSHYYWHMVYRGAGGDNSKNVGDFDRHGEVFLYVHSQMVARYETESLCWSLPLVRPWNQYDDFLENGYAPISSLIEHYGGYPPFSTWYSIRNPDMPDTLNVTIPRARLEEWRDNIYAAIRKGQFETTSKDKPLVLTRDNCLNFVGGILDAQYPSLNKLLGGCSLDEERYGNLHNYGLGKFAEMAYRNKPGEKSPYGLTISNFGAPRDPCFWRWYKHLQYYGRLAATRYPQDITAHRAEVVLSNLVVRLQDRSSPHYLDGHITTFLGPPAVNFMESKAKLGHEPYEWNVQVKSCRRSPPSKENPQTLTLRLFIAAEDLMNDYHSWIEMDRATVQLTDESAITKVRLDTDSSVARKMGNYGEPDPRYASAVFRHGWPQNLMLPVGKVEGMPFVAFCIATDDGIPDPAPAPPFHHYHDPRGMGYPFNRAWTQLTEDSTGKASIRTIISNAELYPFITSTTFKIYRTTKFETKQIIQPTTVTWFNTIRGYFKDADRACMRSEYGYDLYNYDHVMLHADAILDATASKRMPLQMGKYTQDNPDPEHPLWTVKMCENFRAWLLNGCPKGTDPA
What is the function of this protein?
Cyclopenase; part of the gene cluster that mediates the biosynthesis of the aspoquinolone mycotoxins (PubMed:25251934, PubMed:30026518).  Within the pathway, the cyclopenase asqI catalyzes the conversion of 4'-methoxycyclopenin into 4'-methoxyviridicatin (PubMed:30026518).  Cyclopenin can also be converted into viridicatin by asqI (PubMed:30026518).  The first step of the pathway is catalyzed by the nonribosomal pepdide synthetase asqK that condenses anthranilic acid and O-methyl-L-tyrosine to produce 4'-methoxycyclopeptin.  4'-methoxycyclopeptin is then converted to 4'-methoxydehydrocyclopeptin by the ketoglutarate-dependent dioxygenase asqJ.  AsqJ also converts its first product 4'-methoxydehydrocyclopeptin to 4'-methoxycyclopenin.  The following conversion of 4'-methoxycyclopenin into 4'-methoxyviridicatin is catalyzed by the cyclopenase asqI.  4'-methoxyviridicatin is the precursor of quinolone natural products, and is further converted to quinolinone B.  The prenyltransferase asqH1 then catalyzes the canonical Friedel-Crafts alkylation of quinolinone B with dimethylallyl cation to yield dimethylallyl quinolone, which is subjected to FAD-dependent dehydrogenation by the FAD-linked oxidoreductase asqF to yield conjugated aryl diene.  The delta(3') double bond then serves as the site of the second alkylation with DMAPP catalyzed by the prenyltransferase asqH2 to yield a carbenium ion intermediate, which can be attacked by H(2)O to yield a styrenyl quinolone containing a C3'-hydroxyprenyl chain.  The FAD-dependent monooxygenase asqG performs epoxidation of the terminal C7'-C8' olefin.  Finally, after dehydratation of the epoxide at C3 by asqC, the quinolone epoxide rearrangement protein asqO catalyzes an enzymatic 3-exo-tet cyclization to yield the cyclopropyl-THF ring system in aspoquinolone (Probable).
What are the official names of this protein?
Cyclopenase asqI, 4'-methoxyviridicatin/aspoquinolone biosynthesis cluster protein asqI, Aspoquinolone biosynthesis protein I.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
Protein: Y352_RICPR
Sequence: MILLKVNHKPFMLPCVVIASLAYSEQVGWNRQLLPSSGEIKYL
What are the official names of this protein?
Uncharacterized protein RP352.
Protein: RNT_XANC5
Sequence: MRMNEPVDAQPAPSFLPMSRRFRGYLPVVVDVETGGFDWNKHALLEIACVPIEMDTDGRFFPGETASAHLVPAPGLEIDPKSLEITGIVLDHPFRFAKQEKDALDHVFAPVRAAVKKYGCQRAILVGHNAHFDLNFLNAAVARVGHKRNPFHPFSVFDTVTLAGVAYGQTVLARAAQAAGLDWNAADAHSAVYDTEQTARLFCKIANAWPGPV
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: NRFA_ALIFM
Sequence: MKKQWTRRSAAAIAMVTTLLLSSHSFAASENNERVDPRNEAYAKDHADQYDSWRSTSDSVQIEDALAEDPNMVILWAGYGFAKDYNKARGHFYAVDDVRQTLRTGGPTDENSGPMPMACWSCKSPDVGRVIEEQGEDGYFSGKWARLGSEIQNPIGCADCHDTRSEEFKNGGPALALTKPHVERAMDAIGKPFGDQSRLDQQAAVCGQCHVEYYFTGKTKAVKFPWDKGTTVDEMEEYYDEIGFKDWTHKVSKAPMLKAQHPGYETWRDGIHGKNKVTCVDCHMPKVTKEDGTVYTDHKVGNPFDRFEDTCANCHTQSKEMLQSVVATRKAQVLKMKLTAERQIVAAHFEAGAAWDAGATEKEMAPILQDIRHAQWRWDYAIASHGVHMHAPEVALEVLGTAVDKAADARTKLVRLLAKKGITEPVAIPDISTKAAAQKALGMDMEAMKAEKKHFLETVVPEWEEQAKEREARDYEPM
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRUB_HYDCU
Sequence: MAKKQWQKIDGIVLLNKPEGVTSNGLLQQVRRVYNAKKAGHTGALDPFATGLLPICLGEATKISGLLLDSDKRYIATLQLGLETDSGDKDGNPLKTIAVPALSKAMLETVFSQFEGDVMQVPPMYSALKHQGKPLYEYARKGIHIERAARPIHIYELKLIDFENTVVRFEVLCSKGTYVRTLGEDIAKALGTVGHLTGLHRTQTGALTGDEMATLEEIELNKDAYLQPLDLPLKHLQAIHLNAKDTDKILHGGKLAVEEPETLLVRFYDPQQRFIGVGEWQQEKQLLKPKRLFNLNPIGDDHS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: Y070_ANAMM
Sequence: MLDKRLLEVLVCPLTGGELYYDADSCELVSENAGLAFPVHDGIPVMLADEARKLEPDTK
What are the official names of this protein?
UPF0434 protein AM070.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.