PharMolix/UniProtQA huggingface dataset:
Protein: ASPR_HORVU
Sequence: MGTRGLALALLAAVLLLQTVLPAASEAEGLVRIALKKRPIDRNSRVATGLSGGEEQPLLSGANPLRSEEEGDIVALKNYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKCYFSIACYLHSRYKAGASSTYKKNGKPAAIQYGTGSIAGYFSEDSVTVGDLVVKDQEFIEATKEPGITFLVAKFDGILGLGFKEISVGKAVPVWYKMIEQGLVSDPVFSFWLNRHVDEGEGGEIIFGGMDPKHYVGEHTYVPVTQKGYWQFDMGDVLVGGKSTGFCAGGCAAIADSGTSLLAGPTAIITEINEKIGAAGVVSQECKTIVSQYGQQILDLLLAETQPKKICSQVGLCTFDGTRGVSAGIRSVVDDEPVKSNGLRADPMCSACEMAVVWMQNQLAQNKTQDLILDYVNQLCNRLPSPMGESAVDCGSLGSMPDIEFTIGGKKFALKPEEYILKVGEGAAAQCISGFTAMDIPPPRGPLWILGDVFMGPYHTVFDYGKLRIGFAKAA
What is the function of this protein?
Involved in the breakdown of propeptides of storage proteins in protein-storage vacuoles.
What are the official names of this protein?
Phytepsin, Aspartic proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: Y2295_MYCTU
Sequence: MPVEETSTPQKLPQFRYHPDPVGTGSIVADEVSCVSCEQRRPYTYTGPVYAEEELNEAICPWCIADGSAASRFDATFTDAMWAVPDDVPEDVTEEVLCRTPGFTGWLQEEWLHHCGDAAAFLGPVGASEVADLPDALDALRNEYRGYDWPADKIEEFILTLDRNGLATAYLFRCLSCGVHLAYADFA
What is the function of this protein?
Probably plays a role in host phagosome maturation arrest (PubMed:20844580).
What are the official names of this protein?
UPF0167 protein Rv2295.
What is the protein family that this protein belongs to?
Belongs to the UPF0167 family.
Protein: PG049_MONPV
Sequence: MCTNVVRVFVILYLLAECGCIKYDVDDNVHICTHTVMSHINYTSWYYNDKVIALATEDKTSGYISSFIKRVNISLTCLNISSLRYEDSGTYKGVSHLKDGVIVTTTMNISVKANIIDLTGRVRYLTRNYCEVKIRCEITSFALNGSTPPHMILGTVDKWKYLPFPTDDYRYVGELKRYISGNPYPTESLALEISSTFNRFTIVKNLNDDEFSCYLFSQNYSFHKTLNVRNICESEWEALNNNDNASSVPASHNNLTNDLSSMTSQLQNDDNDYSTPMNVDNLIMIVVITMLSIILVIIVVIAAIAIYKRSKYSRHTDN
What is the function of this protein?
Plays a role in the spread of virus to neighboring cells ex vivo.
What are the official names of this protein?
Protein OPG049.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG049 family.
Protein: APAH_STUS1
Sequence: MTTYAVGDLQGCLEPLTCLLERVDFSPSRDCLWLAGDLVNRGPQSLEALRFVRDLESSAITVLGNHDLHLLAVAHNIERMRKSDTLQAILDAPDRADLIDWLRQQKLIHYDAERHTAMVHAGIPPQWSLEKALRRAAEVEQALQDDALLLPFLDGMYGNQPAKWNKELHGVPRLRLITNYFTRMRFCKADGTLDLDAKEGADSAPAGYAPWFSHASRKTRNVKLIFGHWAALEGQCDEPNVFALDTGCVWGNAMTLMNLDSGEMHRCECEHGKPA
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: HSLV_GEOKA
Sequence: MGAFHATTIFAIRHNGASAMAGDGQVTFGNAVVMKHTAKKVRRLFQGNVLAGFAGSVADAFTLFEMFEGKLEQWNGNLPRAAVELAKEWRSDKVLRRLEAMLIVMDKQHLLLVSGTGEVIEPDDGMLAIGSGGQYALAAGRALKKYAGGSMTAKEIAKAALEIAADICVYTNGHIIVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_SHEWM
Sequence: MNIRIGHGFDVHKFGGDSPLLLGGVNVPYETGLIAHSDGDVVLHAISDAVLGAVALGDIGKHFPDTDDDFKGADSRHLLRHCYQLAKDKGFVIGNLDVTIIAQVPKMAPHIQAIREVLSRDFATDLDNINVKATTTEKLGFTGRKEGIAVEAVILLAKA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ESRP1_HUMAN
Sequence: MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLELTEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMNYTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYATEDGLIHTNDQARTLPKEWVCI
What is the function of this protein?
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms.  Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2.  Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT).  Acts by directly binding specific sequences in mRNAs.  Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (PubMed:19285943).  Regulates splicing and expression of genes involved in inner ear development, auditory hair cell differentiation, and cell fate specification in the cochlear epithelium (By similarity).
What are the official names of this protein?
Epithelial splicing regulatory protein 1, RNA-binding motif protein 35A, RNA-binding protein 35A.
What is the protein family that this protein belongs to?
Belongs to the ESRP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURI_PSEE4
Sequence: MNERSAPIGVMDSGVGGLSVLAEIQRLLPNETLLYVADSGHVPYGEKSPDYIRQRLRHIAGFLREQGAKAMVLACNTATVATVADLRALYPDWPLVGMEPAVKPAAAATRSGVVGVLATTGTLQSAKFAALLDRFASDVRVITQPCPGLVECIEAGDLTSPALRQLLAGYVQPLLAQGCDTLILGCTHYPFLRPMLADMVPADVAIIDTGAAVARQLQRLLGERDLLADGPARETAFWTSADPDSLKKILPMLWMQSDRVQSFPL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: RR11_CYCTA
Sequence: MSKPIRKIGSRRNERRIPKGVIHVQASFNNTIVTVTDVRGQVVSWSSAGACGFKGTKRSTPFAAQTAAENAIRTLMDQGMERAEVMISGPGPGRDTALRAIRRSGVLLSFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LGT_BEII9
Sequence: MPLMLVYPAIDPVLVWLGPLPIRWYALAYIAGLLLGWAYARRLAAQPVLWGRRTPPSALEVDDLLVYAAMGVIIGGRLGYVVFYNADFYLEHPLESLSLWKGGMSFHGGLIGTALTIGLLAWRRSIPLAVLTDLAAAAVPIGLCLGRIANFIKPELWGRVADPDFVPFAMVFPGAGSLPRHPSQLYEAFFEGIVLFVILFIAIRLGALRRPGLVTGLFALGYGLARIGCEFFREPDAQLGFLFGGATMGMLLSLPLVLIGLFLVIRAASPKLETA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBA4_DICDI
Sequence: MEKYIKEHTLKPNEIERYGRQLITPDIGVSGQMSLCNSSVLIIGAGGLGCPVALYLSSAGIGTLGLVDYDTVEISNLHRQIGHRESSKGISKAVSLSKTISELNSLIKVNTYETTFTSETAMEIIKNYDIVVDASDNVATRYLVNDACVLTGKPLVSGSALKWEGQITCYNYNNGPCYRCIFPTPPPVETVTKCSDGGVLGPIVGVIGSLQALEVIKILTNNKEGVLSGRLLIYDGMSAVFRTVRIRGKQSGCNVCGDKPTVTQLIDYTQFCQSNYSESAGKVDDRVDKTLIITVEQFNQSIKNNNNNHLLIDVRPKIQFDICSLPNSNNIPIEEIDKKESIEIIEKLIKEKVENNNNNNNNNENRDASDELSVYLVCRRGNKSQDAVKILDEKLKEFRDKFKLLHIKDGLLGWNESIDDSFPIY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a.  Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions (By similarity).
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase MOCS3, Molybdenum cofactor synthesis protein 3, Ubiquitin-like protein activator 4 homolog.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBBA_MYCTO
Sequence: MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGGAL
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: PRIA_CHLMU
Sequence: MDPTHQSFRLYAEVLVSANINKILDYGIPAELEDRVTIGSVVKVPLQRKVTNDKYKFAIVLKIKDSSDFANVIQPIAGISYEGVTLPKDLIDLIFWISQYYFCPLGSTLSLFLPTVYSQTHSTKHQNNVFLGQNAERTQEIIKSIEDPHQIAVLRKLLKTTKPLTPKELIKKTDISTKILDSLSKQGFIRIVDSANLEIQDEQLQYFLPEPPTLTQEQIEAINTISQSLITTKFQTCLLFGVTGSGKTEVYLQVIRKARSLGKSVILLVPEVALTIQTLSFFKMHFGAEVGVLHYKLSESERTQTWHKAARGLINIIIGPRSAIFCPMQNLGLIIVDEEHDGAYKQSDLPPFYQARDVAVMRGKFTNATVILGSATPSLESYTNALSKKYTLSVLSKRASTSIPTKVSLIDMNREMEKTRKKILFSPTVIRSIEQRLAVGEQTIIFFNRRGFHTNVSCSSCKYTLKCPHCDMILTFHKTERILLCHLCNTRLSKPITSCPQCHGTMTLQYRGAGTEKIEALLQDFFPTVRTIRLDSDTTRYRGSHDALIKQFATGKADILIGTQMIAKGMHFPAVTLSVVLSGDSGLYIPDFRAAEQVFQLITQVTGRSGRSYLPGEVLIQTFLPQNSTISHALAQDFPAFYKEEILGRKACNYPPFTRLIRCIFLGKCAEYTLQEAQRMHELIKQNLDAQASLMDISPCGHFKVKDLFHYQFLIKTRNILTVNKQLQDAFSAAKLSSKVRCIVDIDPITTFF
What is the function of this protein?
Involved in the restart of stalled replication forks.  Recognizes and binds the arrested nascent DNA chain at stalled replication forks.  It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
What are the official names of this protein?
Primosomal protein N', ATP-dependent helicase PriA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PriA subfamily.
Protein: UREI_HELPJ
Sequence: MLGLVLLYVGIVLISNGICGLTKVDPKSTAVMNFFVGGLSIVCNVVVITYSALHPTAPVEGAEDIVQVSHHLTSFYGPATGLLFGFTYLYAAINHTFGLDWRPYSWYSLFVAINTVPAAILSHYSDMLDDHKVLGITEGDWWAIIWLAWGVLWLTAFIENILKIPLGKFTPWLAIIEGILTAWIPAWLLFIQHWV
What is the function of this protein?
Functions as a specific, H(+)-activated urea channel that increases the rate of urea entry into the cytoplasm, resulting in activation of cytoplasmic urease at acidic medium pH.  Is essential for H. pylori gastric survival and colonization.  Is necessary for the adaptation of urease activity to the extracellular pH, as in the presence of urea, UreI rapidly enhances the production of ammonia in the extracellular medium when the pH of the medium was decreased to pH5 or below (By similarity).
What are the official names of this protein?
Acid-activated urea channel, Urease accessory protein UreI.
What is the protein family that this protein belongs to?
Belongs to the AmiS/UreI family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FAD21_MYCLE
Sequence: MQNSSVLSFLRERAGLQPDDEAFSFTDYEQDWAGVRKTLTWAQLYQRTLNVAHELRRHGSIRDRAVILAPQGLDYIIAFLGAMQAGFIAVPLSVPQAGSHDERVGAVLADTSPSVVLTTSAVADAIAKYVDHSDTDTVPAILEVDSPNLDVENKSNIRLTDAPSTAYLQYTSGSTRLPAGVMVTHRNLMVNFQQLMADYFAPTNGVAPLDLTIVSWLPFYHDMGLVLGVVAPILGGWRSELTSPISFLQRPARWIQAMATSSHPFSAGPNFAFELAARRTSDADIAGLDLGACQGIISGSERIHPATLNRFSDRFARINFRDDMMLPSYGLAEGTVYAASRPKGSSPEVVYFEPAKLSEGTVKRCEARTGAPLLSYGTPKSPIVRIVDSDTCIECPTGRVGEIWLHGDNVAEGYWHKPEETQRTFGGKLANPSPGTPEGPWLRTGDLGFISEDELFIVGRMKDLLIVYGRNHYPEDIESTVQEITGGRVAAISVPVDETEKLVTIIEVKKRGDSDAEAMQKLVAVKNNITAAISKSHGLNVADLVLVPPGSIPTTTSGKVRRTACVEQYRRQQFSRLDG
What are the official names of this protein?
Putative fatty-acid--CoA ligase fadD21, Acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: MPTX_HUMAN
Sequence: MGMYLLHIGNAAVTFNGPTPCPRSPYASTHVNVSWESASGIATLWANGKLVGRKGVWKGYSVGEEAKIILGQEQDSFGGHFDENQSFVGVIWDVFLWDHVLPPKEMCDSCYSGSLLNRHTLTYEDNGYVVTKPKVWA
What are the official names of this protein?
Putative mucosal pentraxin homolog.
What is the protein family that this protein belongs to?
Belongs to the pentraxin family.
Protein: SYH_RHOJR
Sequence: MSKASTFSAPKGVPDYVPPQSSEFVAVRDGLTRAARLAGYGHIELPIFEDTGLFARGVGESTDVVSKEMYTFADRGDRSVTLRPEGTAGVMRAVIEHGLDRGQLPVKLSYAGPFFRYERPQAGRYRQLQQVGVEAIGVDDPALDAEVIAIADAGFRGLGLDGFRLEITSLGDDTCRPQYRERLQEFLFALPLDEETRRRAEINPLRVLDDKRKEVREMTADAPLMLDHLSDTAKAHFDEVLAHLDALSVPYVVNPRMVRGLDYYTKTTFEFVHDGLGAQSGIGGGGRYDGLMAQLGGQPLSGIGFGLGVDRTVLALAAEGKTAGSTARCEVFGVPLGEEAKAKLVVIAQQLRAQGIRVDLAYGNRGVKGAMKAADRSGAALALVLGDRDIADGTVGIKNLATGDQESVSSADVVARVGAILGA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3B_STRPN
Sequence: MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPNN_SACSN
Sequence: MRKPVRIGVLGCASFAWRRMLPAMCDVAETEVVAVASRDPAKAERFAARFECEAVLGYQRLLERPDIDAVYVPLPPGMHAEWIGKALEADKHVLAEKPLTTTASDTARLVGLARRKNLLLRENYLFLHHGRHDVVRDLLQSGEIGELREFTAVFGIPPLPDTDIRYRTELGGGALLDIGVYPARAARHFLLGPLTVLGASSHEAQESGVDLSGSVLLQSEGGTVAHLGYGFVHHYRSAYELWGSRGRIVVDRAFTPPAEWQAVIRIERKGVVDELSLPAEDQVRKAVTAFARDIRAGTGVDDPAVAGDSGESMIQQAALVEAIGQARRCGST
What is the function of this protein?
Involved in the biosynthesis of forosamine ((4-dimethylamino)-2,3,4,6-tetradeoxy-alpha-D-threo-hexopyranose), a highly deoxygenated sugar component of several bioactive natural products such as the insecticidal spinosyns A and D (PubMed:11358695, PubMed:18345667).  Catalyzes the reduction of the C-3 keto moiety of dTDP-3,4-diketo-2,6-dideoxy-alpha-D-glucose to yield dTDP-4-keto-2,6-dideoxy-alpha-D-glucose (PubMed:18345667).  NADPH is the better reductant, however NADH can also be used (PubMed:18345667).
What are the official names of this protein?
dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase, dTDP-3,4-diketo-2,6-dideoxy-D-glucose 3-ketoreductase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: AROC_METCA
Sequence: MSGNTIGKLFTVTTFGESHGPALGCIVDGCPPGLALSEADLQHDLYRRRPGQSRHTTQRRESDTVKILSGVFEGLTTGTPIGLLIENEDQRSKDYASIADRFRPGHADYTYHMKYGFRDYRGGGRSSARETAMRVAAGGIAKKYLRERLGVEIRGYLAQLGPIRIDPVDWNAIDDNPFFCPDPARVPELEAYMDALRKEGDSSGARVNVVARGVPPGLGEPVFDRLDAELAYALMSINAVKGVEIGAGFGCVEAKGSVFRDEMSPEGFLGNSAGGILGGISTGQDIVASIALKPTSSLRLPGRSVNIRGESVEVVTTGRHDPCVGIRATPIAEAMMAIVLMDHYLRHRGQNQDVVRTLDPIPPSAF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PPNP_PHOPR
Sequence: MLNVNEYFEGQVKSIGFEAQGDRTSVGVMAAGEYTFGTAAPERMTVVKGSMDVKRPGHVEWETFNAGDDFEVPGDSSFEVKITSSTAYLCDYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: ATPE_LACLS
Sequence: MSENVMTLQVITPAGVVYDHHANYITARTTNGEIGILPNMISTIAGLEIDELKVRRPDDETHVDYIAVNGGIIEIKDSLVTIVADSAERNRDIDVSRAERAKIRAEKALEVAKAEKKSDEIKRVEVALHRALNRLNVSSHN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: OTU12_ARATH
Sequence: MGDSSSSTSWSSKKDTEDDRMIAFMLSEEYSKLDGAVGRRLSNLAPVPHVPRINCYIPNLNDATLDHQRLLQRLNVYGLCELKVSGDGNCQFRALSDQLYRSPEYHKQVRREVVKQLKECRSMYESYVPMKYKRYYKKMGKFGEWGDHITLQAAADRFAAKICLLTSFRDTCFIEIIPQYQAPKGVLWLSFWSEVHYNSLYDIQAAPVQHKPKRKHWLF
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation (Probable).  Inactive cysteine protease (PubMed:24659992).
What are the official names of this protein?
OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 12, OTU domain-containing protein 12, Deubiquitinating enzyme OTU12.
What is the protein family that this protein belongs to?
Belongs to the peptidase C85 family.
Protein: ATPB_ECOHS
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGSERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: K1C20_HUMAN
Sequence: MDFSRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVKTTEYQLSTLEERDIKKTRKIKTVVQEVVDGKVVSSEVKEVEENI
What is the function of this protein?
Plays a significant role in maintaining keratin filament organization in intestinal epithelia.  When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
What are the official names of this protein?
Keratin, type I cytoskeletal 20, Cytokeratin-20, CK-20, Keratin-20, K20, Protein IT.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASR_ECO57
Sequence: MKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA
What is the function of this protein?
Required for growth and/or survival at acidic conditions.
What are the official names of this protein?
Acid shock protein.
What is the protein family that this protein belongs to?
Belongs to the Asr family.
What are the subcellular locations of this protein?
Periplasm.