PharMolix/UniProtQA huggingface dataset:
Protein: OBG_MYCSJ
Sequence: MPRFVDRVVIHARAGNGGNGCASVHREKFKPLGGPDGGNGGRGGSIVLVVDPQVHTLLDFHFHPHVVAPSGKQGAGSNRDGAAGADLEVRVPDGTVVLDEEGRVLADLVGAGTRFEAAAGGRGGLGNAALASRSRRAPGFALLGEKGQVRELTLELKTVADVGLIGFPSAGKSSLVSTISAAKPKIADYPFTTLVPNLGVVSAGDHTFTVADVPGLIPGASEGRGLGLEFLRHIERCAVLVHVVDCATMEPGRDPISDIEALEAELAAYRPTLQGDSTLGDLAERPRAVVLNKIDVPDARELADFVRDEVAERFGWPVFEVSTVAREGLRPFIFALWDMVRTYREAQPPVVPRRPIIRPIAVDETGFSVHPDGQGGFVVRGTRPERWINQTDFDNDEAVGYLGDRLARLGVEEELLRLGARPGCAVTIGDMTFDWEPQTPAGVDVQMSGRGTDTRLEQTDRVSAAERKIARRERRQSTDEPGGEE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMP10_BRUSU
Sequence: MKRFRIVAPLALMSLALAACETTGPGSGNAPIIAHTPAGIEGSWVDPNGIASSFNGGIFETRTTDTNEKLAEGNYLYLSPQLVEINMRSIVRGTTSKVNCALVSPTQLNCTSSAGSRFSLTRRNAG
What are the official names of this protein?
Outer membrane lipoprotein omp10, 10 kDa OMP, Minor outer membrane protein omp10.
What is the protein family that this protein belongs to?
Belongs to the rhizobiaceae omp10 lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: DCA15_HUMAN
Sequence: MAPSSKSERNSGAGSGGGGPGGAGGKRAAGRRREHVLKQLERVKISGQLSPRLFRKLPPRVCVSLKNIVDEDFLYAGHIFLGFSKCGRYVLSYTSSSGDDDFSFYIYHLYWWEFNVHSKLKLVRQVRLFQDEEIYSDLYLTVCEWPSDASKVIVFGFNTRSANGMLMNMMMMSDENHRDIYVSTVAVPPPGRCAACQDASRAHPGDPNAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSLVACAVSVHSAGDRSFCQILYDHSTCPLAPASPPEPQSPELPPALPSFCPEAAPARSSGSPEPSPAIAKAKEFVADIFRRAKEAKGGVPEEARPALCPGPSGSRCRAHSEPLALCGETAPRDSPPASEAPASEPGYVNYTKLYYVLESGEGTEPEDELEDDKISLPFVVTDLRGRNLRPMRERTAVQGQYLTVEQLTLDFEYVINEVIRHDATWGHQFCSFSDYDIVILEVCPETNQVLINIGLLLLAFPSPTEEGQLRPKTYHTSLKVAWDLNTGIFETVSVGDLTEVKGQTSGSVWSSYRKSCVDMVMKWLVPESSGRYVNRMTNEALHKGCSLKVLADSERYTWIVL
What is the function of this protein?
Binding of aryl sulfonamide anticancer drugs, such as indisulam (E7070) or E7820, change the substrate specificity of the DCX(DCAF15) complex, leading to promote ubiquitination and degradation of splicing factor RBM39 (PubMed:28437394, PubMed:28302793, PubMed:31693891, PubMed:31452512).  RBM39 degradation results in splicing defects and death in cancer cell lines (PubMed:28437394, PubMed:28302793, PubMed:31693891).  Aryl sulfonamide anticancer drugs change the substrate specificity of DCAF15 by acting as a molecular glue that promotes binding between DCAF15 and weak affinity interactor RBM39 (PubMed:31686031, PubMed:31819272).  Aryl sulfonamide anticancer drugs also promote ubiquitination and degradation of RBM23 and PRPF39 (PubMed:31693891, PubMed:31626998, PubMed:31686031).
What are the official names of this protein?
DDB1- and CUL4-associated factor 15.
Protein: EFTU_CHLPN
Sequence: MSKETFQRNKPHINIGTIGHVDHGKTTLTAAITRALSGDGLASFRDYSSIDNTPEEKARGITINASHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSATDGAMPQTKEHILLARQVGVPYIVVFLNKVDMISQEDAELIDLVEMELSELLEEKGYKGCPIIRGSALKALEGDANYIEKVRELMQAVDDNIPTPEREIDKPFLMPIEDVFSISGRGTVVTGRIERGIVKVSDKVQLVGLGETKETIVTGVEMFRKELPEGRAGENVGLLLRGIGKNDVERGMVVCQPNSVKPHTKFKSAVYVLQKEEGGRHKPFFSGYRPQFFFRTTDVTGVVTLPEGTEMVMPGDNVELDVELIGTVALEEGMRFAIREGGRTIGAGTISKINA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_GLUOX
Sequence: MFYGVDLTSRLMLGTAQYPSPQVLLEAIEASGAQVITVSLRREGAAGGAFRALLAKSRCRLLPNTAGCHTVREAVTTARMAREVFGTSWIKLEVIGHADTQQPDPFALVEAARVLCAEGFDVFPYTTEDLIVGEKLLEAGCKVLMPWGAPIGSGQGLRNLAGLRSMRAHFRDVPLVVDAGIGAPSQAAQAMELGFDAVLLNTAVAKAVDPVGMARAFGRAIQAGQEGFVAGLMPERDMASASTPVFGLAELA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAB_LACSA
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFESWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLLISAISLIAGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGEYVRWNNFLDVLPHPQGLGPLFTGQWNLYAQNPDSGSHLFGTSQGAGTAILTLLGGFHPQTQSLWLTDMAHHHLAIAFLFLIAGHMYRTNFGIGHSMKDLLDAHIPPGGRLGRGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLEHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDILLSSTNGPAFNAGRSIWLPGWLNAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: ASSY_CLOB6
Sequence: MKEKVVLAYSGGLDTSIIIPWLKENYDLDVIAVCVNVGQGDDMDYVKTKAIKSGASKIYVEDVKEEFVVDYLYKAIKSEALYEQDYMLGTSFARPLMAKKLVEIAHKEQAKYICHGCTGKGNDQVRFEVGVKAQDPTIKIIAPWRIWDIKSREDAIDYAKKVGVEVPVTKKKIYSVDKNLWHVSHEGGDLEDLKNEHKEDMYFMVTPPEKAKDEPTYLEIYFEKGAPVKINGEFLNPVDIIDKLNTIGGENGIGIADIIENRLVGMKSRGIYETPAGTLLYAAHKKLESVTLDKYTYQYKKLVSAQYGELVYNGLWFTALREAIDAFVDKTQENVTGTVKLKLYKGNIKPCSVDTEYALYDEGISSFGESELYSHKDAEGFINLFGLPCKIKALKNF
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACBP_GOSHI
Sequence: MGLKEEFEEHAEKVKTLPAAPSNDDMLILYGLYKQATVGPVNTSRPGMFNMREKYKWDAWKAVEGKSKEEAMGDYITKVKQLFEAAGSS
What is the function of this protein?
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters.
What are the official names of this protein?
Acyl-CoA-binding protein, ACBP.
What is the protein family that this protein belongs to?
Belongs to the ACBP family.
Protein: RL13_RHOPB
Sequence: MKTFSAKPAEVTKKWIVIDATGLVVGRLATLVANRLRGKHLPTYTPHVDCGDHVIIVNAAKVVLTGRKRENKVYYHHTGFIGGIKERTAKSILEGRFPERVVEKAIERMIPRGPLGRMQMGNLRVYGGPDHPHEAQQPEPLNVAVMNRKNMRAA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MURD2_XANC8
Sequence: MRISQLEGKAVALWGWAREGRAAYRALRQQLPAQPLTVFCNAEEARDVAALADPALQVQTEASAQALAAFEVVIKSPGISPYREEARAAAAQGARFIGGTALWFAEHAQPDGYVPGAICVTGTKGKSTTTALLAHLLRADGHRTALVGNIGQPLLEVLSPQPPPAYWAIELSSYQTGEVGRSGARPELALVLNLFPEHLDWHGSEAAYVRDKLALVTDGRPRIALLNAADPHLAQLQLPESEVRWFNHPDGWHLRGDVVYRGQQPIFDTANVPLPGEHNRRNLCAVLAAVEALGLDAAALAPAALTFRPLPNRLQWLGSVDGIAYVNDSISTTPHASLAALACFAQQRVALLVGGHDRGLDWQEFAAHMAQQAPLEIVTMGANGPRIHALLAPLAQSAGFGLHAADDLAHAMQLARSALGAQGGVLLLSPGAPSFGVYSDYVARGRHFAQLAGFDPAAISAIPGLGVQ
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanine--L-glutamate ligase, UDP-N-acetylmuramoyl-L-alanyl-L-glutamate synthetase, UDP-MurNAc-L-Ala-L-Glu synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN184_HUMAN
Sequence: MEDLSSPDSTLLQGGHNLLSSASFQEAVTFKDVIVDFTQEEWKQLDPGQRDLFRDVTLENYTHLVSIGLQVSKPDVISQLEQGTEPWIMEPSIPVGTCADWETRLENSVSAPEPDISEEELSPEVIVEKHKRDDSWSSNLLESWEYEGSLERQQANQQTLPKEIKVTEKTIPSWEKGPVNNEFGKSVNVSSNLVTQEPSPEETSTKRSIKQNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCDECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYKCNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIRSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRHCSSLAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTGEKPYNCNECRKTFSQSTYLIQHQRIHSGEKPFGCNDCGKSFRYRSALNKHQRLHPGI
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 184.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOC_DINSH
Sequence: MRGRAGETTMTAALQELAAHIEMKRPDCVISTEIAHDELTVVATPNSIVGLVAFLKTDATCKFSTLIDITAVDYPERAQRFDVVYHFLSMYQNHRIRIRVPVREDDIVPSIISEHPSANWFEREVFDMFGILFSGHPDLRRILTDYGFRGYPLRKDFPTTGYTEVRYDEEKKRVVYEPVNLVQEYRQFDFMSPWEGAEYILPGDEKTDDKAEAKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NKCL_MANSE
Sequence: MNDENRFNVSAVEGESKKNGIHMGANIITRPLRSSVENVERGVAPNSQSEGWHHESGWKRRRSLAQLTREALPRMENYRNSKRALKRPSLGELHGDHLITEEDEKDQNHRDTKSPTPAVGIKLGWIQGVFIPCLLNIWGVMLFLRLSWVVSQAGIGLSLVIIAISAIVCVITTLSMSAICTNGEVKGGGIYYIISRSLGPEFGASVGIIFAFANAVAASMNTIGFCDSLNDLLRSNGLKITEDPINDVRIVGTVALLVMCIICAIGMDWESKAQNFLIAIIVGAMVDFVVGTIMGPKDNSEIAKGFVGLSSATFVENFKSDFRFSEKLDQNFFSVFAIFFPSVTGIQAGANISGDLKDPASAIPKGTLLALLISMVSYTLMVLFAGGGALRDASGNITDLLIVNGTVTDYSSVSLCALNNTCEYGLHNSYSVMQLMSAWGPFIYGGCWAATLSTALTNLLSVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYRGYVLTFFVSLLFLLIADLNTIAPLISNFYLASYALINFCTFHRALVRPLGWRPTFRYYNMWLSLAGFLMCVAIMLLVHWVMSLVTFAIFFTLYLIVHYRRPDVNWGSSTQAQMYKTALSSAHALARTGEHVKNYWPQLLVLAGRPQARPALVDLGNLISKAGSLMIVGDISQEKLSYKVRSARARSDDEWLRGRKVRAFCSRVHGFSFEPGARALVQGSGVGRLAPNVLLMGYKSDWTTCPANDLVSYFNVLHTAFENRLAVAIVRVSGGLDYSAVVSEGAEEGAAGSLTATSSSGELRVRRDGLIMHADSDLDIRDTQPKHNLSNLLTLTTSRSFTISECKEKDKKKKERKPNDMHRQIVYNTASGLELSKFQLAQMSLFQKKQESGTLDVWWLYDDGGLTILLPYIISQRSAWANCKLRIFALANRLHEMELEERNMANLLAKFRIDYSSLTMVQDITDPPQPETKALFDETIKKFTEESASPDCRISDMELQTLAVKTNRQLRLRELLLANSKDARLVVMSLPMPRKGSISAPLYMAWLEMMSRDLPPMLFVRGNHTSVLTFYS
What is the function of this protein?
Electrically silent transporter system.  Mediates sodium and chloride reabsorption.  Plays a vital role in the regulation of ionic balance and cell volume.
What are the official names of this protein?
Bumetanide-sensitive sodium-(potassium)-chloride cotransporter, Na-K-CL symporter.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MAZF_STAAM
Sequence: MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKKKYKLDKDSVILLEQIRTLDKKRLKEKLTYLSDDKMKEVDNALMISLGLNAVAHQKN
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis.  It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA.  Neutralized by coexpression with cognate antitoxin MazE.
What are the official names of this protein?
Endoribonuclease MazF, Toxin MazF, mRNA interferase MazF.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: LPXB_BURM9
Sequence: MAFQLTPLRVALVAGEPSGDLLGASLLGGLHARLPASSRYYGIGGPRMSAVEFDAHWPMEKLAVRGYVEALKHIPEILRIRGELKRQLFAEPPDAFVGIDAPDFNFGLEQALRGAGIPTIHFVCPSIWAWRGGRIKKIVKAVDHMLCLFPFEPELLEKAGVAATFVGHPLADEIPLEPDTHGARIALGLPGGGPVIAVLPGSRRSEIELIGPTFFDAMELMQQREPGVRFVVPAATPALRALLQPLVDAHPSLSVTLTEGRAQVAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLTGQIMRRQGYLPYVGLPNILAGRFVVPELLQHFATPDALADATLTQLRDDANRRALADIFTDMHLALRQNTAQRAAEAVAHVIDSRKPR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: ATHB7_ARATH
Sequence: MTEGGEYSPAMMSAEPFLTMKKMKKSNHNKNNQRRFSDEQIKSLEMMFESETRLEPRKKVQLARELGLQPRQVAIWFQNKRARWKSKQLETEYNILRQNYDNLASQFESLKKEKQALVSELQRLKEATQKKTQEEERQCSGDQAVVALSSTHHESENEENRRRKPEEVRPEMEMKDDKGHHGVMCDHHDYEDDDNGYSNNIKREYFGGFEEEPDHLMNIVEPADSCLTSSDDWRGFKSDTTTLLDQSSNNYPWRDFWS
What is the function of this protein?
Probable transcription activator that may act as growth regulators in response to water deficit.
What are the official names of this protein?
Homeobox-leucine zipper protein ATHB-7, HD-ZIP protein ATHB-7, Homeodomain transcription factor ATHB-7.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: VAMP3_BOVIN
Sequence: MTTNAPAGSSAAAGSSRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGITVVVIIIIIIVVWSISS
What is the function of this protein?
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
What are the official names of this protein?
Vesicle-associated membrane protein 3, VAMP-3, Synaptobrevin-3.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Early endosome membrane; Single-pass type IV membrane protein. Recycling endosome membrane; Single-pass type I membrane protein. Synapse, synaptosome.
Protein: PUR7_VIBVU
Sequence: MSLADQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSARLIKEKGYNVAPDAPLAIMVISDRISAFDCIWHGEHGLNGVPGKGAALNAISNHWFGLFKENGLADSHILDIPHPFVWIVQKAKPVKIEAICRKYITGSMWRAYEKGEREFCGIQLPEGLEKDKALPDLLMTPSTKGILKGIPGVPEADDVNITRQNIADNFAAFNFSSADDIALYEKLLKDGFGVISEALANVGQIFVDTKFEFGYVTDAAGNEKLIYMDEVGTPDSSRIWDAQEYQAGKIVENSKEGFRQFLLNYFPDPDILLNKDRMPEREALARDNELPEEALMAVSRTYINIAEKITGSAIVLSDNPKQEIIDILGREYGLID
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: CHBG_ECO57
Sequence: MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAIDHAVQLSRDEPSLAIGMNFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEEGIALRIDRQPLSNAGDLPANLRSSHGFSSAFYGEEISEALFLQVLDDSSHRGERSLEVMCHPAFVDNTIRQSAYCFPRLTELEVLTSASLKYAIAERGYRLGSYLDV
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_THEP3
Sequence: MHKVVLLRHGESLWNMENRFTGWTDVDLSPKGIEEARESGKTLKAEGYTFDCAFTSVLKRAIRTLWIVLDELDRMWIPVYKSWRLNERHYGALQGLNKAETAKKYGEEQVKIWRRSVDVRPPALEKDDPRYPGFDPRYADLSEEEIPLTENLIDTINRVIPYWESTIAPTIKSGKKVLIVAHGNSLRGLVKYLDNLSKQEIMELNIPTGIPLVYELDDDLKPIRHYYLADEEKVKEKKELVENQGKIQGNS
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: DNAB_RICBR
Sequence: MARNKTNNDKNIANDEASTVLARVLPSNVQAEQMLLGAILTNNELLNYVSEFLRSEHFFEPIHQKIYNGIEVITEKGLIATPITLRSMLANDELFHEMEGAEYLAKLVTMSMMVINPIDYGKIIYDLAIKRYLINIGEEVVNDAYNSSLEFEAKEQIERAESKLYDLASEGINEKSFTKIAIPISESIASINRAMKNNDHVIGISTGLIDLDSKLFGFHNSDLVILAGRPAMGKTAFALNLALNACNNMLIKNKRDNEEVQSVGFFSLEMSSEQLTTRLLSMSAGIDSTTLRTGMINEANYNRLRKEAIALSELSFFIDDTPALTISAIRTRARRMKRKHNLGILFVDYLQLIRGVSKSDNRVNEVSEITQGLKAIAKELNIPVIALSQLSRAVELREDKRPMLSDLRESGSIEQDADIVMFIYREEYYLSRKEPAASDPKHAEKYAEWQDNMSKAHNITDIIIAKHRSGPVGNVQLFYDSQYSKFVNLETKYPVHPR
What is the function of this protein?
Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.
What are the official names of this protein?
Replicative DNA helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DnaB subfamily.
Protein: DPOM_NEUIN
Sequence: MSKFSFFNYRINMRNSHATLGSLPCFIKFNYLSSSSHSKFYSTSTDSPMGHIVSASKSSWYNYYSHKNYDPLTRESFHDELRGFISLYKKQFKEEKFFFMAKIKFNNNDIRSISTVQIGSTDPLEVLRLLEAITSTYMHTHTGISEAVSEPFEYELFSLGDGLPKGNIIFTFKPTSNPSIKTKYEHKSNIKRNKNINLSKKNPLNKFKYNGYTIPNTMDLSQWPNIHFINDGKNAVSLNNIIKSGVDNMTLSFFITINKKYNEITVLLNNTPIFKIKDEKIMSEDDLSSFKRTITENEQDKVYVFENGEMVFFSENVKTSFIKKITRQDLINFENPKIITLDLETRSVPIHPIKEGKDGKEGKVDSIMFPILMSVYNGKFVKSFLFSQSAWETEMMNAFKSIMLRKYDGYKVYTHNFSYFDGIFIIDILSRLGEVKPFMRNGKILKLTFNFTLPNSKRKYTLYFMDSLLILPDSLDKLSNFFNNKVKKLFFPHSFLDDNTIPINYVGKCPDYKYFPKAYTEDFTIEQYQEYANKFKNNNWDLKKELIKYCEIDTIALYQVLVSFQRKIYEKFMIDCTKYPTIPSLAFAIFRKKYLVEDMIPNIKSKLHNIIKLSYFGGICELYKPFGVNIKSYDVNSLYPFAMKYFKMPSGIPKYVKGTLQNIVRFTDSICEVPFGFYNVKVKTPLNLDKPFLPTRLNTPAGTRTAFPLGQWEGWYFSEEILNAMKHGYEFEFIEGYLFEESSMFDEYIDLLYNIKKNSPKESPWYYISKLLMNSLYGRFGLNPEGEEIFITSEEEGDAIIATKEYVTITPLSSGNVLISAKLPEEAFGDMNISVPISSAIAAYSRIHMSHFLTKYSNNIYYIDTDGIKVDIDLDKDEVDSKELGKMKYEYVFEEYTSLGPKVYGGLLYDKKGKLIELVKLRGYSSKLPYNKLKEGLVKDHTLELTQKKWKRKLSESTVYLKNTHLLFL
What are the official names of this protein?
Probable DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PA2BD_CRODR
Sequence: SLVQFEKMIKEETGKNAVPFYAFYGCYCGWGGRGRPKDATDRCCIVHDCCYEKLVKCNTKWDFYRYSLRSGYFQCGKGTWCEQQICECDRVAAECLRRSLSTYRYGKMIYPDSRCREPSETC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that induces myonecrosis and edema upon subcutaneous injections in mice.  In vitro, causes a potent blockade of neuromuscular transmission in young chicken biventer cervicis preparation and produces cytotoxicity in murine C2C12 skeletal muscle myotubes and lack cytolytic activity upon myoblasts in vitro.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 Cdr-13, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURA_VESOH
Sequence: MYKLIIHGGISLNGSVITAGSKNSSLPILFASILANGPITLTNTPHLSDVSTTLRLLMDMGAEFILESDNSLFINGSKLTNLVAQYNLVKTMRASILALGPMLAKYGKAKISLPGGCAIGPRPVNLHLEALENLGATIKVKNGYIYATAKELIGTKIHFKQISVTATENIIMAATLATGITTIYNAAQEPEIVDLVKCLIKMGAIISGAGTSIIIIQGVDELSGVTYSVCPDRIEAGTYLVATAITGGKITIKNVHYQSMHAILEKLLETGADIKTNKNSIILDMKGKRPRAVNIKTSTYPNFPTDMQAQFTALNAIADGYSTITETIFENRFMHIPELSRMGANLVLKGNTVVCKGVKYLTGMPLIATDLRASASLVLAGLVATGTTTIERVYHLDRGYETIEEKLKLLGAQIERVQD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WAP_RABIT
Sequence: MRCLISLALGLLALEAALALAPKFIAPVQVMCPEPSSSEETLCLSDNDCLGSTVCCPSAAGGSCRTPIIVPTPKAGRCPWVQAPMLSQLCEELSDCANDIECRGDKKCCFSRCAMRYLEPILESTPQ
What is the function of this protein?
Could be a protease inhibitor.
What are the official names of this protein?
Whey acidic protein, WAP.
What are the subcellular locations of this protein?
Secreted.
Protein: MSGN1_CHICK
Sequence: MEDTLGSEHSVCLSSWDWKNTAGAFELHSVSSPHSLSPTPSFESYSSSPCPAAAETPYSGGGLVGYGLVDFPPAYLPSPGQARLPKGTKVRMSAQRRRKASEREKLRMRTLADALHTLRNYLPPAYSQRGQPLTKIQTLKCTIKYISELTELLNSVKRA
What is the function of this protein?
Involved in specifying the paraxial, but not dorsal, mesoderm.  May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity).
What are the official names of this protein?
Mesogenin-1, Protein cMespo.
What are the subcellular locations of this protein?
Nucleus.