PharMolix/UniProtQA huggingface dataset:
Protein: PLCX1_MOUSE
Sequence: MQGLEPSRVGRVGEVCRSVHKNVLTVPEHTVGTEAAAPMGDQADWMSQLCPQLWDVPLHHLSIPGSHDTMTYCLNRKSRISRASSWLLHLLGRVVPFITGPVVMKWSVTQTLDVTQQLDAGVRYLDLRIAHAPEGSTRNLCFVHMMYTKALVEDTLTEIAEWLQSHPREVVILACRNFEGMTCELHDYLAGCIVNIFGDMLCPSGEVPTLRQLWAREQQVIVSYEDEATVSRYDQLWPAIPYWWGNAVKTDVLLRFLETMKGQGRPDGLFVAGINITENLCYILLHPVDSLEEMTRRSLPLMTEWVCAQQPGQSPQCTNIIAGDFVDADGFVSKVISLNCKLLSP
What are the official names of this protein?
PI-PLC X domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_FRATT
Sequence: MAKLYFRYSAMDAGKTLDLLKVAYNYEDRGRKPLVLTSAIDKRAGLNKVKSRIGINQDAYSLTDRDNIFEFVENYNSSNKIDCVLIDEIHFFTQEQVWQLAEIVDELNIPVICYGLRTNYLGQPFETAALLLAIADTLEEVKTICHCGKKASFNMMVQNGKAIKQGNPIVVDDDSLKEIDTKYVSVCRKHWKEGVYE
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_SERP5
Sequence: MSKQRKLTEADVTPESVFYQRRKVLQALGITAASLALPHNAQADLLSWFKGNDRPKAPPGKPLEFSKPAAWQAQLDLTPEDKVTGYNNFYEFGLDKADPAANAGGLKTEGWQVRIDGEVAKPITLDIDDLIKRFPLEQRIYRMRCVEAWSMVVPWIGFELGKLIKFAEPNSNARYVAFQTLYDPEQMPGQKDRFIGGGLKYPYVEGLRLDEAMNPLALLTVGVYGKTLPPQNGAPLRLITPWKYGFKGIKSIVHIRLVRDQPPTTWNQSAPNEYGFYANVNPHVDHPRWSQATERFIGSGGILDVKRQPTLLFNGYAEQVASLYRGLDLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: MURD_PHOLL
Sequence: MADYLGKKVVIIGLGLTGLSCVDFFMARGVIPRVMDTRTAPPGKDKLPDGVECHSGSLNADWLMDADLIVVSPGIALATAVLQAAANAGIEIVGDIELFCREATAPIVAITGSNGKSTVTSLVGEMAKAANWQVGVGGNIGLPALELLKKSCQLYVLELSSFQLETTYSLNATAAAVLNVTEDHMDRYPQGVSQYRAAKLRIYHQAKRCIVNAQDPLTLPEMGMDSRCVSFGVDCGDYQLDSENAFLKVHNQSLLATNEIKLTGRHNYANGLVALALADAVGIPREASLATLTVYPGLDHRFQLARLNKGVRWINDSKATNVGSTMAALDGLNLEGTLYLLLGGDGKSADFSPLKPFLCGNKVQLYCFGRDGKQLAQLRPEIATLTETMEQAIRDIAPRLVAGDMVLLSPACASLDQFRNFEQRGHEFTRLAEELG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGT1_CAEEL
Sequence: MEAANEVVNLFASQATTPSSLDAVTTLETVSTPTFIFPEVSDSQILQLMPATLYSGMNWLRDHLDGFSLLALSGCIFVSVLYLVHIIAFFYSIYRLHHKVEPDPTLPGVSVIKPIVGTDKNLYQNLESFFTSQYHSFELLFCFHSEEDEAIEVVRSLIKKHPNIEAKILFEGEPVGMNPKVNNMMPAYRAARYPLVLISDSAIFMRPDGILDMATTMMSHEKMASVTQIPYCKDRQGFHAAFEQIFFGTSHARLYLVGNFLGVVCSSGMSSMMKKSALDECGGMEKFGEYLAEDYFFAKALTSRGCKAAISTHPALQNSASVTVLSFFNRIGRWIKLRIAMMPHLMVVEPLQDCVTSGLIMAFGLNYLGGYSVYKTFGLHLFYWIVMDFSLMTSMQNGKFNFTPFLFVFIWLFREFTSPFIFIKAVLAPTIVWRNNKFKLSWGGRIRTSKNSQKVPEAVSLSKGAV
What is the function of this protein?
Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide to produce glucosylceramides (GlcCer).  GlcCer are known to contribute to the physical properties and physiological functions of membranes and may regulate signal transduction (PubMed:19240113, PubMed:21325339).  Only branched-chain sphingoid bases like 15-methylhexadecasphing-4-enine are used for generating complex sphingolipids in Caenorhabditis elegans (PubMed:7651085).  Together with cgt-3, plays a role in the trafficking of proteins such as mig-14 to the cell membrane in intestinal cells (PubMed:26115433).
What are the official names of this protein?
Ceramide glucosyltransferase 1, CGT-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CLS2_STAES
Sequence: MALHQSNIIINILLVSAFLLNLVFAFIIIFMERRTANSIWAWLLVLVFLPLVGFILYLLLGRQIQREHIFKLAKEDKVGLEMIVDEQLEALKKQDFSKGNHQIVKFKEMVQMLLYNNAAFLTTDNDLTIYTDGHQKFDDLINDIRHAQSYIHIQYYIIHSDNLGKQLLHELEKKAEEGIEVKMLYDDMGSRDLRKKDLKKFRQKGGHAESFFPSKLPLINLRMNNRNHRKIVVIDGTIGYVGGFNVGDEYIGKSKKFGYWRDTHLRIKGDAVNALQLRFILDWNSQSTRDNLTYESRYFPDVDSGGTIGIQIASSGPDEDWEQIKYGYLKMISSAKESIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMVPNKRDHPFVYWATLKNVASLLEAGVNVYHYDNGFLHSKTLVIDDEVASVGTANMDNRSFTLNFEVNAFIYDEGVARSLKQAFINDMKLSNKLTSEEYAKRNLLVKFKEGISQLLSPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase 2, CL synthase 2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NHR68_CAEEL
Sequence: MENKEVCLVCQDFSSGYHYGIPSCNGCKTFFRRTVMKKQKFVCQFDQNCPVDKSIRCACRFCRFEKCLKVGMDKTSLQASRDPIGYTKRNKKTLRHPMNELSGDESNSCTPDRQLSPLRSFENSLNFLAVRERSANELRMSSYLPKRSLKQALCSKPLINDPIFMSKHATVSPRHTFEKLRFITQDDYHYWHERDWFVLTEYAKTFKVFKNMPYHDKTELVCHAAIVIPVLNQVYNSPDYGLDTVVFPDGTYYDRTHEPTRPAGLNRKKYQVLDLVLKPFREMEINFNEFAAFKAITFLNPDADISLESKHAINEERVLITKQLYAYMVQKDGLEKAIYRFGRLILMGTSMSKMACESKEAVWIADFFENIGFTSFAKELIFGDH
What is the function of this protein?
Probable transcription factor that acts in a feed-forward loop with nhr-10 to activate genes, including itself, involved in the vitamin B12-independent breakdown of the short-chain fatty acid propionate (PubMed:30625328).  This pathway is triggered in response to a diet low in vitamin B12, when canonical vitamin B12-dependent propionate breakdown cannot function; the resulting accumulation of propionate is probably sensed by nhr-68 and/or nhr-10 (PubMed:30625328).
What are the official names of this protein?
Nuclear hormone receptor family member nhr-68.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYI_BACTN
Sequence: MGKRFTEYSQFDLSQVNKDVLKKWDENQVFAKSMTERDGCPSFVFFEGPPSANGMPGIHHVMARTIKDIFCRYKTMKGYQVKRKAGWDTHGLPVELSVEKALGITKEDIGKKISVADYNAACRKDVMKYTKEWEDLTHQMGYWVDMKHPYITYDNRYIETLWWLLKQLHKKGLLYKGYTIQPYSPAAGTGLSSHELNQPGCYRDVKDTTAVAQFKMKNPKPEMAEWGTPYFLAWTTTPWTLPSNTALCVGPKIDYVAVQTYNAYTGEPITVVLAKALLNTHFNSKAADLKLEDYKAGDKLVPFKVVAEYKGADLIGMEYEQLIPWVKPVEVSEDGTWKVSGKGFRVIPGDYVTTEDGTGIVHIAPTFGADDANVARAAGIPSLFMINKKGETRPMVDLTGKFYMLDELDENFVKECVDVDKYKEYQGAWVKNAYNPVFMVDGKYDEKAAQAAESLDVALCMMMKANNQAFKIEKHIHNYPHCWRTDKPVLYYPLDSWFIRSTACKERMMELNKTINWKPESTGTGRFGKWLENLNDWNLSRSRYWGTPLPIWRTEDGTSEICIESVEELYNEIEKSVAAGFMKSNPYKDKGFVPGEYTEGNYDKIDLHRPYVDDIILVSEDGQPMKRESDLIDVWFDSGAMPYAQIHYPFENKNILDNREVYPADFIAEGVDQTRGWFFTLHAIATMVFDSVSYKAVISNGLVLDKNGNKMSKRLNNAVDPFTTIEKYGSDPLRWYMITNSSPWDNLKFDIDGIEEVRRKFFGTLYNTYSFFALYANVDGFEYKEADVPMAERPEIDRWILSVLNTLIKEVDTCYNEYEPTKAGRLISDFVNDNLSNWYVRLNRKRFWGGEFTQDKLSAYQTLYTCLETVAKLMAPISPFYADRLYTDLTTATGRDNVVSIHLAEFPKYQEEMIDKELEARMQMAQDVTSMVLALRRKVNIKVRQPLQCIMIPVADEEQKAHIEAVKALIMNEVNVKDIKFVDGAAGVLVKKVKCDFKKLGPKFGKQMKAVAAAVAEMSQEAIAELEKNGKYALNLDGAEAVIEAADVEIFSEDIPGWLVANEGKLTVALEVTVTEELRREGIARELVNRIQNIRKSSGFEITDKIKITISKNTQTDDAVNEYNTYICNQVLGTSLDLADEVKDGTELNFDDFSLFVNVIKD
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_VIBPA
Sequence: MPLQSPLTFSDEQINIGELKQELEKFSSTQKQEFLNHHPVTSLVLARAEYMDLLLTRLWQYFGFNDIYNISLVAVGGYGRGELHPLSDIDILVLSNNKLPTALEAKISEFITLLWDLKLEVGHAVRTVNECAQIGRDDLTVATNLQEARLLCGSEDTFQALKKVVLSDSFWPSETFYRAKIQEQRERHARYHDTTYNLEPDIKSTPGGLRDIHTLSWVARRHFGATSLLEMSRYGFLTDAEYRELVECQDFLWRVRFALHIELRRYDNRLTFAHQAQVAENLGYVGEGNRGVEMMMKEFYRTLRRVAELNKMLLKLFDQAIINGGATENAEILDADFQRRGSLIEARKPALFQARPETILDMFLHIANDSTIEGVSPPTLRQLRTARRRLNKFLHTIPAAREKFLALCRHPNALHKAFSLMHRLGVMAAYLPQWSQIVGQMQFDLFHAYTVDEHSIRLLKHINTFNNPDNHAKHPICCDIYPRMQKKELLIIAAIFHDIGKGRGGDHSVIGEGEAYDFCIEHGLSKPEAKLVGWLVRHHLLMSVTAQRRDIYDPDVITEFAKQVRDEESLEYLVCLTVADICATNPELWNAWKRTLLAELFYSTQRALRRGLENPVDVRERIRHNQQMASALLRKEGFSARQIEVLWQRFKADYFLRHTHTQIAWHCAHLLRMDDPNKPLVLISKKATRGGTEVFVYTKDQPALFATVVAELDRRNFNVHDAQIMTSKDGHVIDTFMVLDQHGEAIDESRHAAVIKHLTHVLEAGRPTKIKTRRTPNKLQHFNVKTKVDFLPTKGKKHTLMEFVALDTPGLLAKVGRTFADLNINLHGAKITTIGERAEDLFILTSEAGGRLSEEQQNELRDKLIEKLSDAVTA
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: PIMB_CORGL
Sequence: MSASRKTLVVTNDFPPRIGGIQSYLRDFIATQDPESIVVFASTQNAEEAHAYDKTLDYEVIRWPRSVMLPTPTTAHAMAEIIREREIDNVWFGAAAPLALMAGTAKQAGASKVIASTHGHEVGWSMLPGSRQSLRKIGTEVDVLTYISQYTLRRFKSAFGSHPTFEHLPSGVDVKRFTPATPEDKSATRKKLGFTDTTPVIACNSRLVPRKGQDSLIKAMPQVIAARPDAQLLIVGSGRYESTLRRLATDVSQNVKFLGRLEYQDMINTLAAADIFAMPARTRGGGLDVEGLGIVYLEAQACGVPVIAGTSGGAPETVTPATGLVVEGSDVDKLSELLIELLDDPIRRAAMGAAGRAHVEAEWSWEIMGERLTNILQSEPR
What is the function of this protein?
Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM) (PubMed:18421567, PubMed:18178556, PubMed:19395496).  Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose residues (Ac1PIM2) (PubMed:18178556, PubMed:19395496).  PimB also catalyzes the addition of a mannosyl residue from GDP-Man to the position 6 of phosphatidyl-myo-inositol bearing an acylated alpha-1,2-linked mannose residue (Ac1PIM1) to generate monoacylated phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose residues (Ac1PIM2) (By similarity).  The addition of the second mannosyl residue by PimB preferentially occurs before the acylation of the mannosyl residue transferred by PimA (By similarity).  Also able to transfer a mannosyl residue from GDP-Man to the position 6 of a phosphatidyl-myo-inositol (PI), but this reaction is very slow (By similarity).
What are the official names of this protein?
GDP-mannose-dependent monoacylated alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase, Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase, Alpha-mannosyltransferase, Alpha-ManT, Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase, Phosphatidylinositol alpha-mannosyltransferase, PI alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: ARLY_ACIBS
Sequence: MTTSSNPPNSAAPNQTSGMWGGRFSEATDAFVAEFTASVQFDQRFYKQDIAGSIAHATMLAKVGVLTEAERDDIIEGLSTIRAEIEAGTFEWRIDLEDVHMNIESRLTQRIGITGKKLHTGRSRNDQVATDIRLYLRDEIDDILGLLERLQKGLLGLAAKNVNTIMPGFTHLQTAQPVTFGHHLLAWFEMLVRDTERLQDCRKRVNRMPLGSAALAGTTYPIDRAYTAELLGFEAVSENSLDAVSDRDFAIEFNAAASLIMMHLSRMSEELILWTSAQFKFVNIPDRFCTGSSIMPQKKNPDVPELIRGKSGRVFGDLISLLTLMKGQPLAYNKDNQEDKEPLFDAIDTVRGSLMAFADMIPALVPNVEIMREAALRGFSTATDLADYLVKKGVAFRDAHEIVGKAVALGVAEEKDLSELTLEQLQQFSDLITADVFDKALTLEASVNARDHIGGTSPKQVEAAIARAHKRLEQLYA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_BACFN
Sequence: MIKREDVYKIGLFNKPHGIHGELSFTFTDDIFDRADCDYLICRLDDIFVPFFIEEYRFRSDSTALVKLEGVDTAERARMFTNVEVYFPVKHAEEAGPGELSWDFFVGFRVEDVRHGALGKVTDVDTSTVNTLFVVDRDGDELLIPAQEELIAGIDQKHKIITVDLPEGLLSLDECDDEES
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_ALKEH
Sequence: MSRVKRGVTARAKHNKVLKKAKGYYGARRKSFRIARQAVIKSGQYAYRDRRQRKRQFRALWIQRINAGARQHGLSYSRFINGLQQAGVDLDRKVLADLAVNDKAAFGALAEKAREALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ATPL_PROM0
Sequence: MDSITSAASVVAAGLAVGLGAIGPGLGQGNAAQGAVEGIARQPEAEGKIRGTLLLSFAFMESLTIYGLVVALVLLFANPFS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: TIG_HISS2
Sequence: MSFNIETTQGLERRVNITVPSEAVEQAVREELKRVAKNARIDGFRKGKVPAQMIEKRFGASVRQDVLGDLLQKHFFNVMLENKVNLAGRPEFTVEQFEAGKELKFTATFEVYPEVQLQGLDKIKVEKPVVEISDADIDKMLDILRKQQATWIETQDVAKADDRVTIDFVGSVDGEEFEGGKSTDFVLAMGQGRMIPGFEEGIIGHKAGEQFEINVTFPETYHAENLKGKAAKFSITLKKVEVMQLPELTDEFVAKFGPNTKNVADLRNEIAKNMQRELKNALVSRIKTQVIDGLLEQNPIEVPTAAVEQEIEVLRNQAAQRFGGNAQQAAQLPRELFEEQAKRRVQVGLLFSEVISSNELKADEERVKAMIADIASAYEQPAEVIEYYSKNKELMNNIRNVVLEQQAVDAVLTKAQVTEKASSFDEVMNPQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: HTXG_STUST
Sequence: MMNETGMAAAPAEAAWRIWQAPRQQTAFRQLMTAFSYPGRVVPLADGAESALLLVLTTLVDSACALADPLHALSSDDLRRLGVRSASVEAAEFVLADGNRLLEATPRLGSLENPEQGATVVMRVSRFGEGPHLRLTGPGIQHEQVLQVSGIDPGWWKQRSEWNAHFPLGVDLILVSGHEVAVLPRTTHINLKGAH
What is the function of this protein?
Belongs to an operon involved in hypophosphite oxidation.  Exact function not known.
What are the official names of this protein?
Putative C-P lyase subunit protein HtxG.
What is the protein family that this protein belongs to?
Belongs to the PhnH family.
Protein: SYA_COREF
Sequence: MQTHEIRERFTNHFVNAGHTAVPSASLILDDPNLLFVNAGMVPFKPYFLGQQTPPFANGTATSIQKCVRTLDIEEVGITTRHNTFFQMAGNFSFGQYFKEGAITHAWTLLTNPVEEGGYGLDPERLWVTVYLDDDEAAEIWEKKIGVPAERIQRLGMADNYWSMGVPGPCGPCSEIYYDRGPKYGNEGGPAVDDSRYLEIWNLVFMEFERGEGTGKDSFEIIGELPKKNIDTGMGVERVACILQGVENVYETDLLRPVIDVAETLTGATYGRDNTADIRFRVIADHSRTGMMLILDGVTPGNEGRGYILRRLLRRIIRSARLLGATGETMEKFMNTIMDTMTPSYPEIAENRERILRVAITEERAFLKTLVSGTHLFEEAAASIKSSGSTTVAGAQAFALHDTYGFPIDLTLEMAAEAGLEVDVEGFESLMAEQRSRAKADSQAKKHGHADLSIYREWVDNHPTVFTGFEELESQSRVLGLLSDGTRINEAAEGQEVEVILDQSPLYAESGGQLGDRGRILMGDTVVDIQDVQKIGKKLWVHKAVVANGGLAVGDEVVAAVDKQWRHAARQAHTATHLIHAALRQVLGPTAVQAGSMNKPGYLRFDFNYTDQLTPEQLNQIQAITNEAVDTDWAVNTIETSLEEARAMGAMALFGENYGDLVRVVEIGGPFSMELCGGTHVEHSSQIGPVALLGESSIGSGVRRIEAYSGLNSFNYLSKERALAESLSSILKTPSTDLPERISQLLDKLKAAEKEIATLHRRELAAKSEEFITGAEEINGIRAVMVRVQDGLDAGDLRTLATTLRDKLSNGEGLVVVASRSEDGTKVPFVAGATKQAVARGVHSGNLIKLIGSYIDGRGGGKPDMAQGSGSDIDGLDAAFNAVRAELENL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_STRMK
Sequence: MINSLLTRVFGSRNERQLRQLNRIVAKINALEPEIEKLSDEQLQAKTPEFKQRIADGEALDKVLPEAFAVCREAGRRVLGMRHYDVQLIGGMVLHLGKIAEMRTGEGKTLVATLPVYLNALEGKGVHVVTVNDYLARRDAAQMGKLYNWLGLSVGVVYPGMPHSDKREAYAADITYGTNNEFGFDYLRDNMALSKADRYQRGLHYAIVDEVDSILIDEARTPLIISGPADDSPELYIRVNRVVPHLVKQEAEDGEGDFWVDEKGKQVHLSEAGMEHAEQLLVEAGILNGETEGLYAAQNLTVVHHLNAALRAHAIYQRDVDYIVRDGEVVIVDEFTGRTLAGRRWSDGLHQAVEAKEGVPVQRENQTLASITFQNLFRMYKKLSGMTGTADTEAFEFQSIYGLEVVVIPTNRPTIRKDSPDQVFLNRKGKFNAVLADIEECAKRGQPVLVGTTSIETSEMLSEHLSKAGVKHEVLNAKQHDREATIVANAGRPGAVTIATNMAGRGTDIVLGGSLEAELHALGEDATDEQKAAVKADWQKRHEAVKAAGGLHIVGTERHESRRIDNQLRGRSGRQGDPGSSRFYLALEDNLLRVFGGERVQKMMRMMGMKEEDVIEDRLVTRMIEKSQRKVEAHNFDIRKNLLDFDDVNNDQRKVIYAQRDELLDAESVKDNVDGIRDDVIFDVVARFVPPNSIDEQWDLRGLEATLESDFGLQMSLTDLVKEHEELDAEAIAAKVQERVNQHFAEKEASVGEETMRALEKHVMLTVLDQSWKEHLARMDYLRQGIYLRGYAQKQPKQEYKKEAFELFSDMLENVKREVVTLLSRVRIRSDEEVQALEAAERQQAEARLSQSQFQHQDVGGYSADEEAAQVQAAQQGVAQMQRDEPKIGRNDPCPCGSGKKYKHCHGQLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: HIS1_MYCPA
Sequence: MLRVAVPNKGTLSEPATEILAEAGYRRRTDSKDLTVIDPVNQVEFFFLRPKDIAIYVGSGELDFGITGRDLVGDSDAPVRERLALGFGSSSFRYAGPAGRDWKIADLAGKRIATAYPNLVRKDLAERGIEATVIRLDGAVEISVQLGVADAIADVVGSGRTLSLHNLVAFGEPLCDSEAVLIESDRGGQDDTQAARDQLVARIQGVVFGQQYLMLDYDCPRAVLDKATAITPGLESPTIAPLADADWVAIRALVPRRGVNEIMDELAAIGAKAILASDIRFCRF
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTC_SALG2
Sequence: MDQKQIEEIVRSVMASMGQDVPQPVAPSTQEGAKPQCAAPTVTESCALDLGSAEAKAWIGVENPHRADVLTELRRSTAARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLSPEAIDALKSQCVMNPDVQVVVSDGLSTDAITANYEEILPPLLAGLKQAGLNVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRVATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: DNAJ_ZYMMO
Sequence: MSELDYYSLLEVERTADDKTIKTSYRRLAMRYHPDRNPGDSDAEERFKAISEAYDCLKDPQKRAAYDRYGKDAFQGGGGFGGFGGGAQDFGGFSDIFESVFGEFMGGRGQARSSVQRGADLRYDLKISLEEAFKGKTVDIEIDVASVCDACHGSGAKAGSGRKTCDTCHGSGRIRVQQGFFVVEQSCPVCQGKGEVISDPCPECHGEGRCEKHKTLSVNIPAGVDDGTRIRLSGEGEAGVHGGPAGDLYIFIHVTPHQVFQRESYNLFAHVPISFTKAALGGSIHVPSLDGEQYEISIPAGIQSGKQLKRRGAGMPVLNGRGRGDLIIQIDVETPTRLTAKQRELLEQFRETETGEECPKSSGFFSKLKTILTGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.