PharMolix/UniProtQA huggingface dataset:
Protein: CPEB4_MOUSE
Sequence: MGDYGFGVLVQSNTGNKSAFPVRFHPHLQPPHHHQNATPNPAAFINNNTAANGSSAGSAWLFPAPATHNIQDEILGSEKAKSQQQEQQDPLEKQQLSPSPGQEAGILPETEKAKAEENPGDSSSENSNGKEKLRIESPVLTGFDYQEATGLGTSTQPLTSSASSLTGFSNWSAAIAPSSSTIINEDASFFHQGGVPGASANNGALLFQNFPHHVSPGFGGSFSPQIGPLSQHHPHHPHFQHHHSQHQQQRRSPASPHPPPFTHRSAAFNQLPHLANNLNKPPSPWSSYQSPSPTPSSSWSPGGGGYGGWGASQGRDHRRGLNGGITPLNSISPLKKNFASNHIQLQKYARPSSAFAPKSWMEDSLNRADNIFPFPERPRTFDMHSLESSLIDIMRAENDSIKGRLNYSYPGSDSSLLINARTYGRRRGQSSLFPMEDGFLDDGRGDQPLHSGLGSPHCFTHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGEIDKRVEVKPYVLDDQLCDECQGARCGGKFAPFFCANVTCLQYYCEYCWAAIHSRAGREFHKPLVKEGGDRPRHISFRWN
What is the function of this protein?
Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR (PubMed:17024188).  RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (By similarity).  Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE-regulated mRNAs in conditions in which global protein synthesis is inhibited (PubMed:28092655).  Required for cell cycle progression, specifically for cytokinesis and chromosomal segregation (By similarity).  Plays a role as an oncogene promoting tumor growth and progression by positively regulating translation of t-plasminogen activator/PLAT (PubMed:22138752).  Stimulates proliferation of melanocytes (By similarity).  In contrast to CPEB1 and CPEB3, does not play role in synaptic plasticity, learning and memory (PubMed:24386439).
What are the official names of this protein?
Cytoplasmic polyadenylation element-binding protein 4, CPE-BP4, CPE-binding protein 4, mCPEB-4.
What is the protein family that this protein belongs to?
Belongs to the RRM CPEB family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Cell projection, dendritic spine. Postsynaptic density. Cell projection, axon. Cell projection, growth cone. Endoplasmic reticulum. Cytoplasm, perinuclear region.
Protein: RS21_DESVH
Sequence: MISLPGVYLNEDDYNFDIALRRFKKQVEKAGILSEMKKRQHYEKPSVMRKKKKAAARKRLLKKIRKMNMA
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RS15_GEOSL
Sequence: MLVTDKKKEIITTHKLHDSDTGSPEVQIALLTERIIYLTEHFKVHKKDHHSRRGLLKIVGQRRRLLDYLKKKDVERYRSIIEKLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RSMH_PHEZH
Sequence: MTTPHVPVLMQEVVDALAPAPGRTIIDGTFGAGGYTRAILATGASVVAFDRDPTVRRFAEGLPADRFRLVEARFSEMDEVLGEGAADGVALDLGVSSMQLDQAERGFSFMQDGPLDMRMGASGPTAADLVNTAEPAELARIFFVYGEERESRRIARAIARRREEQPFTRTLELADFIEKALGGRRGAKIHPATRAFQGLRIAVNEELSELEAGLAAAERVLKPEGRLCVVTFHSLEDRIVKSFLSVRAGRTPAGSRHAPPVRQGPAPSFQLLFNGARGPSETEVAANPRARSAKLRAAVRTDAPVWRDAA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPDA_SALMO
Sequence: MSKLKYFFPDSQDFIDPSFDFVRETRNEHRVRQRDDHYPHEVFPHPYDGMLVSKAVVDGLGGGESKYTRAQRLRYFRNGMKHFFRLPDNMQTMGDCGAFTYVNQDVPPYRVEEVIEFYETSRFNYGVSLDHIIFGYEKPGESFSGEVLAECRRRQDITLTLAQDFLVKSQKSCFTPFGVAHGWNKKSYRQSVEALLAMGYKNITMGGMVPLKTAQILETLEEIKPLLKSDTQVHLLGIARPESFADFIRLGVTSIDSTTPLQQAFKDRKNNYHTPEGRAYTAVRVPQFDANPSLSRKIKSGVIDQDVARHLEKDAMHALFEYDNNALSLEKTLEAVLAYERLHSGEKEAEKIRADYERTLGDRPWRKCECNICRSIGINVIIFRGAERNRRRGFHNIQVLYNRLQYTLSLRSEDKS
What is the function of this protein?
Part of the dpd cluster involved in the insertion of 7-deazaguanine derivatives in DNA (PubMed:26929322, PubMed:30159947).  DpdA may insert 7-cyano-7-deazaguanine (preQ0) into DNA with the help of DpdB (PubMed:30159947).  DpdA and dpdB are necessary and sufficient to synthesize 2'-deoxy-7-cyano-7-deazaguanosine (dPreQ0) (PubMed:30159947).
What are the official names of this protein?
DNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA-guanine transglycosylase family.
Protein: HTPG_SALPA
Sequence: MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDSELRVRVSFDKDKRTLTIADNGVGMNRDEVIDHLGTIAKSGTKSFLESMGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGDKPENGVFWESAGEGEYTVADITKNDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSEIKDDEYNEFYKHIAHDFTDPLTWSHNRVEGKQEYTSLLYIPSQAPWDLWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSNDLPLNVSREILQDSTVTRNLRSALTKRVLQMLEKLAKDDAEKYQTFWKQFGLVLKEGPAEDHANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKNSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKAFQSVAKADESIEKLADEVDENAKEAEKALEPFVERVKTLLGDRVKEVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQSVPEVKYIFELNPDHVLVKRTADTEDEAQFKEWVELLLDQALFAERGTLEDPNQFIRRMNQLLVS
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_KLEP7
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RSMH_STRPB
Sequence: MTKEFHHVTVLLHETVDMLDIKPDGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIKDNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLTAYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKKIRK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMO4_RAT
Sequence: MAKKVAVIGAGVSGLSSIKCCLDENLEPTCFERSSDFGGLWKFAEASEDGMTRVYRSLVTNVCKEMSCYSDFPFHEDYPNFMSHEKFWDYLREFAEHFGLLKYIRFKTTVRSVTKRPDFSETGQWEVVTETEGKQDRAVFDAVMVCTGQFLSPRLPLESFPGIHKFKGQILHSQEYRIPDAFRGKRILVVGLGNTGGDVAVELSGIAAQVFLSTRTGAWVRSRSSVGGYPLNMMQTRWRNFLAQVLPSRFVSWNQERQMNKIFNHENYGLSIAKGKKPKFIVNDELPTCILCGKITMKTSVKDFTESSIVFEDGTIEANIDVVIFTTGYEFSFPFFEEPLKSLCTKKVILYKRVFPPNLERSTLAIIGLISLTGSILVGTEFQARWATRVFKGLCNIPPSQKLMAEAIKKEELIKRGVIKDTSQDKLDFISYMDELTQCIGAKPNIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGRWDGARNAILTQWDRTVKPLKTRTVPKSQEPASLSRYLKTWGAPVLIVSLLLIYKSSLFLELVQSKLQGRFSPSRILWYIPQNS
What is the function of this protein?
This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides.
What are the official names of this protein?
Dimethylaniline monooxygenase [N-oxide-forming] 4, Dimethylaniline oxidase 4, Hepatic flavin-containing monooxygenase 4, FMO 4.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: LFTR_HERA2
Sequence: MTKRLSPQLLIYGYAQGIFPMDEDGQIYWYDPDPRAIIPLDERFHVSSSLQRTIRRQTFEIRFDTAFRETMQACSERDETWISQEFIEIYSQLHAGGLAHSVEAWQDGEMVGGLYGVGLAGLFAGESMWSKARDASKVALVALVERLRAGGFQLLDTQFITPHLATFGAYEIPRAEYKQLLVKALQCSATF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NR1H3_MOUSE
Sequence: MSLWLEASMPDVSPDSATELWKTEPQDAGDQGGNTCILREEARMPQSTGVALGIGLESAEPTALLPRAETLPEPTELRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGARYVCHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAQATSVSPRVSSPPQVLPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHDPLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
What is the function of this protein?
Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:18055760, PubMed:19520913, PubMed:20427281).  Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES.  LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides.  Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.  Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).  Induces LPCAT3-dependent phospholipid remodeling in endoplasmic reticulum (ER) membranes of hepatocytes, driving SREBF1 processing and lipogenesis (PubMed:28846071, PubMed:25806685).  Via LPCAT3, triggers the incorporation of arachidonate into phosphatidylcholines of ER membranes, increasing membrane dynamics and enabling triacylglycerols transfer to nascent very low-density lipoprotein (VLDL) particles (PubMed:25806685).  Via LPCAT3 also counteracts lipid-induced ER stress response and inflammation, likely by modulating SRC kinase membrane compartmentalization and limiting the synthesis of lipid inflammatory mediators (PubMed:24206663).
What are the official names of this protein?
Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear receptor subfamily 1 group H member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: UNG_RFVKA
Sequence: MRRVFLSHEPYVIEYHEDWENIITRLVDMYNEVAEWILKDDTSPTPDKFFKQLSVSLKDKRVCVCGIDPYPRDATGVPFESHNFTKKTIKYIAETVSNITGVRYYKGYNLNNVEGVFPWNYYLSCKIGETKSHALHWKRISKLLLQHITKYVNVLYCLGKTDFANIRSILETPVTTVIGYHPAAREKQFEKDKGFEIVNVLLEINDKPSIRWEQGFSY
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.  Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity.  Binds to DNA (By similarity).
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Protein: YNV5_SCHPO
Sequence: MYPFSFDPSSKLPVTGIYNILLFNLFPLATYLVETFCFFRRWKIACTLLCSITVILAYRMCAVYHHVGYKDVSTFGLAYGFLIMMSLRTCFLSWRDMVPSRNDPVQISAVKRRRPFIRNARWNFVDYALSLRKYGWTDDVVPPYCRKVLTYKSLGIRTAVYVGAFCFVNCFKTRLSNWMLLPISANPWYIQVAFCVTSGFFSYLFINALYYLFAIIFVPLGIWDIAEYPLMMGNVSKTTSVNDFWSRDWHVCTKPYFRVIAWDPTIALTGSKFLASCSCFFLSALFHDFAYWSISGRCSPAFFFQLLIQPFLINLEKRIPLLRKYHYWVLIIEMLINGTYGMGVVLLKFKWKTCSQI
What are the official names of this protein?
Uncharacterized membrane protein C3H7.05c.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: GLMM_VIBC1
Sequence: MSDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTKKVIIGKDTRISGYMLESALEAGLAAAGLKATFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGTKLPDDIELAIEAELDKDIECVESAELGKATRLNDAAGRYIEFCKSTFPSDLSLANVKIVVDCAHGATYHIAPNVFKELGADVVAMGVEPNGTNINAEVGATDVRALQKRVVEEQAHLGLAFDGDGDRIIMVDHLGNKIDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEQLLAKGWKIGAENSGHVILLDKVTTGDAIVAALQVLASVVGSEMTLHDLSQGMTLYPQVLENVRFVGNSNPLEAQAVLDSVAAVEAELGDKGRVLLRKSGTEPLIRVMVEGEDAELVQSSALKIAEAVKASC
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: HSLO_YERPB
Sequence: MSNHDQLHRYLFANHAVRGELVSVNETYQQVLANHDYPPAVQKLLGEMLVATSLLTATLKFDGDITVQLQGGDGPLTLAVINGNNRQEMRGVARVKGEISDDSTLQEMVGNGYLVITITPAQGERYQGVVALEGETIAACLENYFMQSEQLPTRLFIRTGHVADKAAAGGMLLQVLPAQERNEDEFDHLAQLTATIKAEELFTLPANEVLYRLYHQEEVTLYEPQNVSFRCTCSRQRCADALVTLADDDVTEMLEQDGNIDMHCEYCGNHYLFDAVDIATLKNGNSASSEQIH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS4A_HUMAN
Sequence: MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKLKDYLRSKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSMMIDDLLTPCSPGDPGAMEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES
What is the function of this protein?
(Microbial infection) In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 4A, Protein SKD2, VPS4-1, hVPS4.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein. Midbody. Cytoplasm, cytoskeleton, spindle. Note=Membrane-associated in the prevacuolar endosomal compartment. Localizes to the midbody of dividing cells, interaction with ZFYVE19/ANCHR mediates retention at midbody (PubMed:24814515). Localized in two distinct rings on either side of the Flemming body.
Protein: RS4_RHOE4
Sequence: MARYTGPITRKSRRLRVDLVGGDQAFERRPYPPGQHGRARIKESEYLLQLQEKQKARFTYGVMEKQFRLYYKEANNRPGKTGENLLRILESRLDNVVYRAGLARTRRQARQLVTHGHLLVNNKKVDIPSYRVSQYDIIDVKEKSLSTLPFQVARETVGDRPVPGWLQVVGSRLRILVHQLPERAQIDIALQEQLIVEYYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RS5_FERNB
Sequence: MSEIAEKIKQAGETFEERIIEIRRTTKVTKGGKNLSFRVLAVVGNRNGKVGVGVGKAREVPDAIRKALVSARRNIIEIPVVKGTIPHEVVGRQDAAKILMKPAAPGTGIIANGTVRAILELAGVQNVLTKAMGSTNPVIMAQATVNGVKNLYSIDKIAALRDITPAQVVRGVKKEG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PYRE_ECOHS
Sequence: MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERGRGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RS2_NITOC
Sequence: MANVTMRQMLEAGVHFGHQARYWNPKMAPYIFGKRNNIHIINLEETLPLYMEATNYLGRLAANKGTVLFVGTKRAAQEPVREEAGRCGMPYVNSRWLGGMLTNFQTVRRSIKRLHDLEAMIQDGSLDRLKKREALTVRRDRDKLENNLGGIKNMTHLPDALFVIDVEHERIAVDEAAKLGIPVVAVVDTNSDPRKADYIIPGNDDAIRAIRLYLRGIADGIIDGRTTAAAASASKASKDEFVEMEEASEEETLTESLSEKSASTDASVT
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RS8_CAMJJ
Sequence: MINDIISDSLTRIRNAGMRKLETTKLLHSKVVEALVGIFQAKGYIESFNVIEEDKKKFINVVLKYDEKGKSVINELKRISKPGRRVYKGKDEIKRFKNGYGTIVVSTSHGVLANDEAYKAGVGGEILCTIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PFKA_STAAS
Sequence: MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1135_STRZT
Sequence: MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASVFEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEMESILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILHYAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFSYREKTDLI
What are the official names of this protein?
UPF0758 protein SPT_1135.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: ATPD_POLSJ
Sequence: MAELATIARPYAEALFKASGSDLGAAAAWLDELAAIAANVQLQQFAGNPGVTVTQTFDVISGVAKSQLPDAAKNFLRTVIENGRISVLPEIAAQFRVLKNAQSGSSDATVYSAFPLEGPALADLAATLEKRFGRKLNFAVELEPALIGGVRVVVGDEVLDTSVKARLEQMKVALIS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RT72_SALH5
Sequence: MNKPRFNGTPVASLDSLSAMLGIERKRLDWIVKSVSMSYKQFKVETGKNKKERQIFEPKRSLKGIQKKINKEIFEKIDYPHYLHGALSGRDYISNAAVHTRKRTVICLDITNFYPSISKKDVCSIFKNLMRFSPDVSLCLTELVTLNNKVPQGGCCSSYIANLLFFNSEYNLYNRLKSMGLSYSRLLDDITISSDKDLSSEEKTKVIKLVHGMVNQYRLSINESKTTIEHSKDSSSKLSVTGLWVKHGVPKLTKENRRYIRYLVYICKKQGAYERHTKEYHDLWNRCSGKVAQMSRLGHVQAVELRAILSEIMPVYDDYKISKLKLMAKHYLNKFTPPLTDDQIRKIDRMLYDFDIVGRTNKNLAKLYRRKLVALLPDR
What is the function of this protein?
Reverse transcriptase (RT) component of antiviral defense system retron Se72, composed of a non-coding RNA (ncRNA), this reverse transcriptase (RT) and the following cold shock-like protein.  Expression of retron Se72 confers protection against bacteriophage lambda.  At multiplicity of infection (MOI) of 0. 02 cultures slow growth when infected with lambda but do not collapse, at MOI 2 cultures enter growth stasis (PubMed:33157039).  Responsible for synthesis of msDNA (a branched molecule with RNA linked by a 2',5'-phosphodiester bond to ssDNA).  The retron transcript serves as primer (from a conserved internal G residue) and template for the reaction, and codes for the RT (By similarity).  The DNA segment is predicted to be 72 bases long (Probable).
What are the official names of this protein?
Retron Se72 reverse transcriptase, RT.
What is the protein family that this protein belongs to?
Belongs to the bacterial reverse transcriptase family.
Protein: PRIB_SHIBS
Sequence: MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).  During primosome assembly it facilitates the complex formation between PriA and DnaT.
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: HIS4_ALIF1
Sequence: MIIPALDLIEGQVVRLFQGDYGQVTEYKVDPAEQFNLYHQAGANWLHLVDLTGAKDTTARQLDLIARLLASTPANIQIGGGVRNEDDVQDLLNAGAQRVVVGSTAVKQPELVKGWMEKYGAEKIVLALDINIDENGTRNVAISGWQEDSGVTIEALLEDYLTVGLKHVLCTDISRDGTLQGSNVELYVDLCKQYPQVQFQSSGGIGSLDDIAALKGSGVAGVIVGRALLDGKFTAEEAFQCWQSE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RETR2_RAT
Sequence: MASSGGGNTGAGGTSGLGLGLGLGLCMGEATGDAEEEAAAAEAVGRLATSLWLRLRGWEAVLAAAQRLLVWEKPLHSLVTAATLNGLFWLLSSSSLRPFFLLSISLLTYFLLDLWHPRFLPDVSAPPPEEPHSDSEGAGSGAQPHLLSVPELCRYLAESWLTFQIHLQELLQYKRQNPAQFCARVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLLMQLDYSMKAEADALHHKHDKRKRQGKNAPPAGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEEALSRELGDGEETELAPPEDLLSAPPALSKQALDTEEEGAADKETLLQLSSPLHFVNTHFNGAGSPQEGVKCPPGGPVETLSPEAVSGDLMAPSSTLSPQLCLAESGPVTLLSPSVLPSLPQDSPQALTAPEEEEALTTEDFELLDQGELEQLNAELGLGPEMPPKPPDVLPPPPLGPDSHSLVQSDQEAHAVVEP
What is the function of this protein?
Endoplasmic reticulum (ER)-anchored autophagy regulator which exists in an inactive state under basal conditions but is activated following cellular stress.  When activated, induces ER fragmentation and mediates ER delivery into lysosomes through sequestration into autophagosomes via interaction with ATG8 family proteins.  Required for collagen quality control in a LIR motif-independent manner.
What are the official names of this protein?
Reticulophagy regulator 2.
What is the protein family that this protein belongs to?
Belongs to the RETREG family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.