PharMolix/UniProtQA huggingface dataset:
Protein: GHRA_SHISS
Sequence: MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALVWHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLNPSVPLFRLEDTGMGEQMQEYAVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRFPLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITRPAEAVEYISRTIAQLEKGERVCGQVDRARGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX214_APOSC
Sequence: EIPQNLGSGIPHDRIKLPNGQWCKTPGDLCSSSSECCKAKHSNSVTYASFCSREWSGQQGLFINQCRTCNVESSMC
What is the function of this protein?
Neurotoxin with probable ion channel impairing activity.  Is both paralytic and lethal, when injected into lepidopteran larvae.
What are the official names of this protein?
U1-cyrtautoxin-As1b, U1-CUTX-As1b, Aptotoxin IV, Aptotoxin-4, Paralytic peptide IV, PP IV.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXH_GRAFK
Sequence: MEKDLANYRRSYEKGELLERDIPDDPYILFESWFNLADNSKNVEEANAMSISTVGKDLMPKTRVVLLKSFDPDGLYFYTNYDSVKGRDLDENPKCCISFFWPSLEKQIIIQGEVVKVSSKKSEEYFHSRPRGSQLGAHASNQSSVIPSREYLEERLTKLEQKYLKKEIPKPKEWGGFLFKPVAFEFWQGRASRLHDRILFTKKDDNWKIERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: UBIA_BURM7
Sequence: MLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVVIFALGTLLMRSAGCAINDYADRDFDRHVKRTAERPLTSGKIRAWEAIAIAVGLALVSFLLILPLNGLTKELSVVAVFVAATYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMIAWAMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAAMLGIYVWLGAALHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGVLFAGIAAHYALAVR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENGB_CHLCH
Sequence: MNITSASFVASYTSLHALPEAVLPEIVFAGRSNVGKSSLLNSLTGLKGLAKTSAKPGKTRQINYFLINELFYFVDLPGYGYAAVSQSEKAAWGQLLANYIERRDAISLVVVLVDSRHPFMENDVAMLEFLEFHGRPYGIVMTKSDKLNQSEKSKCQRVAKTYAAKAKFVVNYSSFSGAGKALLLSHIDHSIISQ
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NBP35_CANGA
Sequence: MSTEVISTSVVSEPTQEILPAEYSLDAPEPEHCPGPESEMAGKADACQTCENKDICESLPKGPDPDIPLITENLSGIKHKILVLSGKGGVGKSTFTTMLSWALSADDNLQVGAMDLDICGPSLPHMLGCTDEVVHESNTGWTPVYVAENLAAMSIQFMLPEDDSAVIWRGNKKNLLIKKFLKDVVWDDLDYLVVDTPPGTSDEHISINKYMKESGIDGALVVTTPQEVALLDVRKEIDFCRKAGINILGLVENMSGFVCPNCKGESQIFKPTTGGGEALCKELGIKFLGSVPLDPRIGRCSDEGESFLDEFPDSPATLAVLNVVEELRDAVGDV
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.  Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NBP35, Nucleotide-binding protein 35.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: T38BA_XENLA
Sequence: MESLSELSVQFSQLSMFPFFDMAHYVVSVMSAREQAGALDIAARSPMASWFSAMLYCFGGGILSSILLAEPPIAVLSNTTNIMLASTIWYMVYYFPYDLFYNCFFFLPIRLIIAGMKEVTRTWKILSGVTHAHSHYKDALLVMITIGWARGAGGGLISNFEQLVRGVWKPESNEFLKMSYPVKVTLIGAVLFTLQHGHYLPISRHNLMLIYTMFLVLIKVTMMLTHSTASPFLPLETPLQRILFGQRQKPSEVRQSASSSGAKGKPSKKTLDKDSGEQSKKKDS
What is the function of this protein?
Monovalent cation channel required for maintenance of rapid intracellular calcium release.  May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
What are the official names of this protein?
Trimeric intracellular cation channel type B-A, TRIC-B-A, TRICB-A, Transmembrane protein 38B-A.
What is the protein family that this protein belongs to?
Belongs to the TMEM38 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: EMF1_ARATH
Sequence: MGSSIKINSISIDLAGAANEIDMVKCDHFSMRGFVAETRERDLRKCWPFSEESVSLVDQQSYTLPTLSVPKFRWWHCMSCIKDIDAHGPKDCGLHSNSKAIGNSSVIESKSKFNSLTIIDHEKEKKTDIADNAIEEKVGVNCENDDQTATTFLKKARGRPMGASNVRSKSRKLVSPEQVGNNRSKEKLNKPSMDISSWKEKQNVDQAVTTFGSSEIAGVVEDTPPKATKNHKGIRGLMECDNGSSESINLAMSGLQRRKSRKVRLLSELLGNTKTSGGSNIRKEESALKKESVRGRKRKLLPENNYVSRILSTMGATSENASKSCDSDQGNSESTDSGFDRTPFKGKQRNRRFQVVDEFVPSLPCETSQEGIKEHDADPSKRSTPAHSLFTGNDSVPCPPGTQRTERKLSLPKKKTKKPVIDNGKSTVISFSNGIDGSQVNSHTGPSMNTVSQTRDLLNGKRVGGLFDNRLASDGYFRKYLSQVNDKPITSLHLQDNDYVRSRDAEPNCLRDFSSSSKSSSGGWLRTGVDIVDFRNNNHNTNRSSFSNLKLRYPPSSTEVADLSRVLQKDASGADRKGKTVMVQEHHGAPRSQSHDRKETTTEEQNNDDIPMEIVELMAKNQYERCLPDKEEDVSNKQPSQETAHKSKNALLIDLNETYDNGISLEDNNTSRPPKPCSSNARREEHFPMGRQQNSHDFFPISQPYVPSPFGIFPPTQENRASSIRFSGHNCQWLGNLPTVGNQNPSPSSFRVLRACDTCQSVPNQYREASHPIWPSSMIPPQSQYKPVSLNINQSTNPGTLSQASNNENTWNLNFVAANGKQKCGPNPEFSFGCKHAAGVSSSSSRPIDNFSSESSIPALHLLSLLDPRLRSTTPADQHGNTKFTKRHFPPANQSKEFIELQTGDSSKSAYSTKQIPFDLYSKRFTQEPSRKSFPITPPIGTSSLSFQNASWSPHHQEKKTKRKDTFAPVYNTHEKPVFASSNDQAKFQLLGASNSMMLPLKFHMTDKEKKQKRKAESCNNNASAGPVKNSSGPIVCSVNRNPADFTIPEPGNVYMLTGEHLKVRKRTTFKKKPAVCKQDAMKQTKKPVCPPTQNA
What is the function of this protein?
Transcription repressor that regulates phase transition during shoot, flower and seeds development.  Controls leaves development, shoot architecture and flowering by delaying both the vegetative to reproductive transition and flower initiation.  Participates in polycomb group (PcG) protein complex-mediated (including EMF2) silencing of the flower homeotic genes AGAMOUS (AG), PISTILLATA (PI), and APETALA3 (AP3), as well as of some regulatory genes such as ABSCISIC ACID INSENSITIVE3 (ABI3), LONG VEGETATIVE PHASE1 (LOV1), and FLOWERING LOCUS C (FLC) during vegetative development.  Required for histone methylation or for maintaining a stable histone methylation (e. g.  H3K27me3) pattern of repressed target genes (including genes involved in salt stress response and flower development); this repression is counteracted by ULT1 (PubMed:23632855).  Can bind non specifically DNA (both double- and single-stranded) and RNA.
What are the official names of this protein?
Protein EMBRYONIC FLOWER 1.
What are the subcellular locations of this protein?
Nucleus. Note=Follow a speckle-like pattern.
Protein: RS6_DESHY
Sequence: MKAYEVLYVIRPDLDDEAVAATVDKLSEVVTNNGGADVAIDKWGKRRLAYEVNDYREGFYILMNFNGEARTAQEVERIMKISDAVVRFLTTKKED
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PRSE_ECOLX
Sequence: MKKIRGLCLPVMLGAVLMSQHVHAADNLTFKGKLIIPACTVQNAEVNWGDIEIQNLVQSGGNQKDFTVDMNCPYSLGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYNSNNSGIGNAVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSATATLVASYS
What is the function of this protein?
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0. 5-1. 5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.
What are the official names of this protein?
Fimbrial protein PrsE.
What are the subcellular locations of this protein?
Secreted. Fimbrium. Note=At the tip of the pili.
Protein: NIFW_GLUDA
Sequence: MMGILDELRGLSAAEDFFRTLGVKYDAEVLNVARLHILRRMGTYLSQAELEPDEDAARAQCRAQLQRAYDDFTRSTPIAERVFKVHRDAVRPSGGFVSLSELTQDGT
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: RF1_METNO
Sequence: MIAIPSDRLDAILARHDIVTATLSAGEADSESFVQLSRELSDLDDVVAAIRAYRAADAELRGVEAMLEEGDPEMRALAAEEKPEVEAARDAAAKALQILLLPKDSADEKSAILEIRAGTGGDEAALFAGDLFRMYARYADLKGWKVEVVSESPGTMGGYREVVAEVKGRGVFARLKFESGAHRVQRVPETETQGRIHTSAATVAVLPEAEEVDIHVNEADLKIDTMRAQGAGGQHVNKTESAIRITHMPSGIVVFVQEERSQHKNRARAMAVLRARLYEQERSQKDAARAADRRAQVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLEEVLAGTALDELVDALVTEHQAALLAAEGLG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_ECOLI
Sequence: MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_SHEPW
Sequence: MSTTNILLLCGGGGDEHAISLLSANYFETSLATLPQFNVLRVELDVNGHYRTAAGESCELNSRRQIRFDADNRAPWEVDFAIPCIHGFPGETGDIQSYFELINLPYFGCKAEASRNCFNKITAKMWFSALNIPNTPYLFLNEMSDVSIEQATNALVNWGSIFVKAASQGSSVGCYRIDNQEDVASTLAQAFTYSDYVIVEKTISARELEVAVYEIDGEIVATVPGEVICSSNNFYTFDEKYAANSKAQTQVVADISKEVSDLIRQYAISAFKGMKLRHLSRIDFFLTDDGEVLLNEINTFPGLTPISMFPKMLQNHGHSFPDYLLSNINSTD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V2045_VACCW
Sequence: MLNFSLCLYPVFILNKLVLRTQSIILHTINNASIKNR
What are the official names of this protein?
Uncharacterized protein VACWR204.5.
What is the protein family that this protein belongs to?
Belongs to the orthopoxviruses VACWR204.5 protein family.
Protein: RL2_NEIMB
Sequence: MAIVKMKPTSAGRRGMVRVVTEGLYKGAPYAPLLEKKNSTAGRNNNGHITTRHKGGGHKHHYRVVDFKRNKDGIPAKVERIEYDPNRTAFIALLCYADGERRYIIAPRGIQAGAVLVSGAEAAIKVGNTLPIRNIPVGTTIHCIEMKPGKGAQIARSAGASAVLLAKEGAYAQVRLRSGEVRKINVDCRATIGEVGNEEQSLKKIGKAGANRWRGIRPTVRGVVMNPVDHPHGGGEGRTGEAREPVSPWGTPAKGYRTRNNKRTDNMIVRRRYSNKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CLPP1_CHLFF
Sequence: MTLVPYVVEDTGRGERAMDIYSRLLKDRIVMIGQEITEPLANTVIAQLLFLMSEDPQKDIKVFINSPGGYITAGLAIYDTIRFLGCDVNTYCIGQAASMGALLLSAGTKGKRYALPHSRMMIHQPSGGIIGTSADIQLQAAEILTLKKHLANILSECTGQPVEKIIEDSERDFFMGAEDAISYGLIDKVVSSAKDTKDKDTIS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_BUCBP
Sequence: MNWNKRINHKLNMHIFNKKFRVKVAVQKNNNRIINVNGMQYINFSSNDYLGLRNNARIVQAWKTAATRYGIGSTGSSLITGYSTIHQSLEEKLAKWLDYPKAILFISGYTANTAIISTLIQKNDRIFMDKLSHSSILEPSYNSSGKCYRFIHNNPSSLMNKFYSSSGKNPLIITEGIFSMDGDIAPLSIISSFSKKIKGLLMVDDAHGIGVSGYNGKGSCEQHRVKPDILTITFGKAFGISGAAVLCSNNIAEYLWQFSKHLMFSTAMPIAQAYAIRQALYCIQHADKLRRKLQENINFFLKNSQCLSHLLKCSHTAIQPIIIGDNEETMILSDQLKSKGIWVNAIRPPTVPNKSSRLRITLNALHTKEDIEQLIESIYKLYDR
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: XPOT_MALGO
Sequence: MASTPEEQLVKAVEIASNAAAVSDADLVAQALAFLEQLKQVTHESWSVGWTIWTARTEDGSAPKYEHAPRLFGLNLVDEFLDKHIHSVSEAVNALAFLQESALAYLQSEFVHGHGEQGIVFMKNKLAQTLSLLMVQTYSLSSSYSFLSAALSLCTTHPSADTDSGLNVMATDLMMRVLHDLSLSLGSDATLRSVRGKDRLQRDALVRDEIRTHHAASMAELMWRVIQDSLRTLQIPDAGGTTTASSPQQLTAGNAGPLASVAMAVVGDYASWIDISLVVTIDTVQILYNALDAQHMPLRYATADTLCEIVSKGMKPADKLGLIECLRLDTVLTQLELSTRGQGEAQTELREHLARLVNALCTELCKIAEDTTGAQADTRDAAHTKLLVFLQPALSFLADEYDEPAEQVLPCLHLVLSLYKKTKRQNENMGLPSLSAPTLEFVTQLIALALQKLKFDADIDWQDSSLVGGPADADADESEDDDEQLVRFYELRKQLQVILGAIAAIDEPLVSNTIQTLVANTLGSVASPTELPWEQAEVCLYAAFSCGEILSSIRGNKIGLGAHSYVQIPSEPGKAPARNVRQSLSVYQALPPNTLGEILQLLFRSRIGDHAHPVVQLQYFECVVRYASCFVLWSDLLPNALEAFLDQRGLCQPHLGMRRRLNYLFYRFVRDTRTAIPSEIVPRLLESLPLAVNAVLPEVPPEEDVLVKATEKASAFDSQLYLFESCGLLMSQLGHVPETQVMLFKAMTQPLVEQLLQVVQAFGGDPDNLQLVLQVHHLILALSTITKGFPDYDMNRPTEPAWIEELKPITEQILLALTALNRFSIVREAARGAFARIVTSAGPAVLPYIPTLIHALVHQVTEAELVDLLNFFGLITHKYKDNVRSVMDDVFGVLVTRIFSFLNQGIQGTDDMVRRSDTERAYFGLVHALLSAGLDDVLVSEKNQGQLESVLQSHVYYASHGEPVTQRAAISALAWLVQLWARPSEKAIPGFEQFVYDAILPLVFQVPTKPSFDQSDAQAQLVLSELAGLLKSLHTARGDEFLHYLSSIYLPGVQCPPELAVELTKNIQSLDVKPLKRYLDTFIAQSRGGA
What is the function of this protein?
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.  Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).
What are the official names of this protein?
Exportin-T, Exportin(tRNA), Karyopherin-beta, tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: EFTU_KLEP7
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGSARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKIIELAGHLDTYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETAKTTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTINPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBSL1_MOUSE
Sequence: MKAGSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPTVVWEKGGQQLVASERLSFPEDGAEHGLLLSGALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAPEPEPESSECPLPTPGTGEGAPKFLTGPQSQWVLRGEEVVLTCQVGGLPEPKLYWEKDGMALDEVWDSSHFKLEPGRGASDEGASLTLRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPRESPPQDPDENPKPVLEPLKGAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHLEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIVVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGAVRRLVIHKLKADDDGVYLCEMRGRVRTVANVTVKGPILKRLPRKLDVLEGENAVLLVETQEAGVQGCWSRDGEDLPDTCQSSCGHMHALVLPGVTREDAGEITFSLGNSRTTTLLRVKCVKHSPPGPPVMVEMFKGQKNKVLLTWKPPEPPPETSFIYRLERQEVGSDDWIQCFSIEKAGAVEVPGDCVPTEGDYHFRICTVSEHGRSPHVVFNGSAHLVPTARLVSGLEDVQVYDGEDAVFSLDLSAIIQGSWFLNGEQLQSNEPEGQVEPGALRYRIEQKGLQHRLILQAVKHRDSGALVGFSCPGVQDSAALTIQESSVHILSPQDKVSLTFTTSERVVLTCELSRVDFPATWYKDGQKVEESESLIVKTEGRKHRLILPEAQVRDSGEFECRTEGVSAFFGVTVQDPPVHIVNPQEHVFVHAITSECVRLTCEVDREDTTVHWYKDGQEVEESDIIVLENKGPHHRLVLPAARPSDGGEFQCVAGDERAYFTVTITDVFSWIVYPSSEVHVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLEKEDTIRRLVLPSVQLEDSGEYLCEIHDESASFTITVTEPPVRIIYPQDEVTLHAVSLECVVLTCELSREDAPVRWYKDGLEVEESEALVLQSDGPRRRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARSLDLQFGAPGHVELRCEVAPAGSQVRWYKDGLEVEVSDALQLGAEGPARTLTLPHAQPEDAGEYVCETRDEAVTFNVSLAELPVQFLAPEAAPNPLCVVPGEPVVLSCELSRASAQVFWSHNGSPVQQGEGLELRAEGPRRILCIQAADLAHTGVYTCQSGASPGAPSLSFNVQVAELPPVKLVSELTPLTVHEGDDATFQCEVSPPDAEVTWLRNGAVITAGPQLEMVQNGSSRTLIIRGCQLKDAGTVTARAGAADTSARLHVRETELLFLRRLQDVRAEEGQDVHLEVETGRVGAAGTVRWIRGGEPLPLDSRLTTAQDGHVHRLSIHGVLLTDQGTYGCESRHDRTLARLSVRPRQLRELRPLEDVTVHEGGSATFQLELSQEGVTGEWAQGGVRLHPGPKCHIQSEGRTHRLVLSGLGLADSGCVSFTADTLRCAARLTVREVPVTIVQGPQDLEVTEGDTATFECELSQTLADVIWEKDGQALSLSPRLRLQALGTRRLLLLRRCCSSDAGTYSCVVGTARSEPARLTVREREVSVLRELRSVSAREGDGATFECTVSETEITGRWELGGRALRPGGRVRIRQEGKKHILVLSELRTEDTGEVCFQAGPAQSLARLEVEALPLQMCRRPPREKTVLVNRRAVLEVTVSRPGGHVCWMREGVELCPGNKYETRRHGTTHSLVIHDVRPEDQGTYSCQAGQDSADTQLLVDGD
What is the function of this protein?
Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity.  It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer.  Acts as a regulator of the Cul7-RING(FBXW8) ubiquitin-protein ligase, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain.  Required to localize CUL7 to the Golgi apparatus in neurons (By similarity).
What are the official names of this protein?
Obscurin-like protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Note=Colocalizes with CUL7 at the Golgi apparatus in neurons.
Protein: ISPE_YERPB
Sequence: MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQIRLLTPIAGVENEQNLIVRAAKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAATVLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAEGIGEKLQPAEPVEKWYLVIHPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYAPSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PROB1_RHILO
Sequence: MQSLKKYRRITVKIGSALLVDRASGLKRDWLDSLADDIAVLAQGGAEILVVSSGAIALGRTILGLGKRALKLEESQAAAAVGQIALAGAWSDALGRGALKSGQILLTLGDTEERRRYLNARATISTLLKMKAVPVINENDTVATSEIRYGDNDRLAARVATMMGADLLVLLSDIDGLYTAPPARDPKAKFIPVVDRITPDIEAMAGAAASELSRGGMRTKLDAGKIATAAGTAMIITSGTRLSPLMAIERGERATFFRPSANPVKGYKTWIAGQLEPAGRLTVDAGAVGALASGKSLLPAGVKLVSGNFSRGDTVAILSPDGREIARGLVAYDAADAVRIAGLKTAEIETVLGYEARSAMIHRDDLVVSHAGGDISGG
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase 1, Gamma-glutamyl kinase 1, GK 1.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNF_PROMH
Sequence: MKTGYLWAIASALLVTVAQLLLKIGMSELPDLQLEKQWFDLHWLWANIIPISVVFVGLIGYVLSMVCWLLTLRTIPLNKAYPLISLSYVFVYILAVVLPWFQETLSWSKTIGIIFIMLGVWLISQKTEQTTSH
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEBB_MOUSE
Sequence: MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQTRFQNACRDGRSEIAFVATGTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLHRLDGMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEARRQQDPSPGSNLGGGDDLKLR
What is the function of this protein?
Forms the heterodimeric complex core-binding factor (CBF) with RUNX family proteins (RUNX1, RUNX2, and RUNX3).  RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.  The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters (Probable).  CBF complexes repress ZBTB7B transcription factor during cytotoxic (CD8+) T cell development.  They bind to RUNX-binding sequence within the ZBTB7B locus acting as transcriptional silencer and allowing for cytotoxic T cell differentiation (PubMed:18258917).
What are the official names of this protein?
Core-binding factor subunit beta, CBF-beta, Polyomavirus enhancer-binding protein 2 beta subunit, PEA2-beta, PEBP2-beta, SL3-3 enhancer factor 1 subunit beta, SL3/AKV core-binding factor beta subunit.
What is the protein family that this protein belongs to?
Belongs to the CBF-beta family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIFK_MAGO7
Sequence: MATARPSIVGPDSGPESPFPYKMEGKVISGFGRGSKELGIPTANLPVDATISPWISSISSGVYYGWASLQLPPSHPESPSSSSCSPYVVFPMVMSIGYNPFYNNTERSAEVHILHKFTADFYDAPMRLLILGFIRDEKNYDSLEALVKDINTDCDVARTSLDRKAWVPQGGLLHPAVDVREKQGDLDGSWLVRPNDSPSA
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
What are the official names of this protein?
Riboflavin kinase, Flavin mononucleotide kinase 1.
What is the protein family that this protein belongs to?
Belongs to the flavokinase family.