PharMolix/UniProtQA huggingface dataset:
Protein: RL4_LACLM
Sequence: MAKVSLFKQDGSQAGEVTLNDSVFGIEPNESVVFDVVISQRASLRQGTHAHKNRSAVSGGGKKPWRQKGTGRARQGSTRSPQWRGGGTVFGPNPRSYAYKLPQKVRQLALKSVYSTKVTDGKLIAVDTLDFAAPKTAEFAKVISALSIERKVLVVLPNEGNEFAELSARNLENVKVTTANSASVLDIVSADKLLVVQSALTQIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RESB_BACSU
Sequence: MKQVKCECGHINPVGTVLCESCGRALQETQPPLADMRYDGSARRSQTYNKTIIDKIWNFFSSVKVGIWLIVITLAASAFGTIFPQEAYLPPGAQADTYYKEQYGTFGQLYYLLGFHHLYGSWWYLLLIASIGISLVICSLDRVIPLYRALKNQGVRRSPAFLRRQRLFSETVTVLNGESKEKIVTLLKKKHYRIREKEGSILAEKGRFSRWGPYVNHIGLIIFLIGAMLRFVPGMYVDETLWVREGETAAIPGTDGKYYLKNNQFSVETYNSKTEKKVFADAIDRVGDGRVAKNFQTDAVLYKREGKIVYGEKPKLEKVTEEDIRVNQPLRFDSFSVYQVDYKENQLDQMVFQLIDKKTKKSFGSLKINLLDPDSVYDLGNGYKVEIASYLPDFYFNQDGEPSTKTKIPNNPAFVFNIITPDKPKGEKSFVAIQETIEGSGNNKYKLKFDHVETKNITGLTVRKDLTLWVLAVGGAIFMIGVIQGMYWQHRRIWLHSQDGAVMVAGHTNKNWFGLKKDLAFILADSGLTEPVDQKELIKTQK
What is the function of this protein?
Required for the biogenesis of c-type cytochromes.
What are the official names of this protein?
Cytochrome c biogenesis protein ResB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UP04_PSEMZ
Sequence: ENGQLDGVIDPK
What are the official names of this protein?
Unknown protein 4.
Protein: Y419_STAA3
Sequence: MEYIKKIALYMSVLLLIIFIGGCGNMKDEQKKEEQTNKTDSKEEQIKKSFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGTWTILTGFSKSNKPGVLDDEGMVLYLNRNAKKATGYYFVNKVYDDISKNHNEKKYRVELKNNKIVLLDNVEDKKLKQKIENFKFFSQYADFKDLKNYQDGNITTNENVPSYEAQYKMNNSDKNVKKLREIYPITTNNSPNLKLYIDGDIKGSSVGYKKIEYKFSKDKGQETTLRDYLNFGPSEGENVE
What are the official names of this protein?
Uncharacterized lipoprotein SAUSA300_0419.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: HV364_HUMAN
Sequence: MMEFGLSWVFLVAIFKGVQCEVQLVESGEGLVQPGGSLRLSCAASGFTFSSYAMHWVRQAPGKGLEYVSAISSNGGSTYYADSVKGRFTISRDNSKNTLYLQMGSLRAEDMAVYYCAR
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 3-64.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: HIS1_SYNJB
Sequence: MLDGRPDSPPITIALAKGALLPEAIQCLQQVGIDFSRFLDPGNRLLRIESPTRLNGQRYEALLVRTHDVPVYVEYGQAQLGIVGYDVLRERYAGTEARVAHLLDLQFGHCRMSVALPQDSPYHSAAQLPAHARVASKFVGCAREYFDRLDLPVELISLYGSVELAPLTGMADAIVDLVATGRTLRENGLIERDCLFESTARLIAHPISYRVNQQPIRELITQIRERWLGSLLVGG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPR3_EMENI
Sequence: MSSIARPPDPCLVAVVLIARSRAGPRFVFHYPPRPLADNALRPPKARRTSRSRSRQNSKGNDSTSSDDSHSSSDEDEEEAPSQNLNNSNNSNNNSYIAGSRRSSNFGLDDSNTLSENQRPGSISSSRAYLRKRGANSDAETDSGVGSDRQEDGSRESDGPNRVPWESILGLPVDVWEKLLSPSRSWHKRRFELGINDLAFVGWPVFVREDGNWRKQRRKKKKKQRAEWESGELGHNDATEDSQDDGNDAVAASTETLSPFSALHPISQRPSVPNSRSSQMSSEPLDADDKDMMTMFNVVFVLDPPLLEYSMRVREIYDNVIKKFSKALKWEQSRTNYVWRECQHILNIKEKAKEKRSSLNSLYADIISQSSLARAIRTLYTSISASKIASVTLSPDVSISLQIPPLTSTPYLPGPTDQAYPGLWLTTADSISPADDPMTDDNSAPHQVLAKHFALLLLDNEATIIKDVEAAGGALAPPLVHYIRCSSPTKSFVQISQISGMPLPTIQFLASHLVYWRRARAIPPLHQRDTYIVSPNCDLSKLEVASAAYKVAFPTLPSLPKMLSALSGTPRPYGNFIPSKDHKATYFLILAWLLRGGWVTQLRSFARVKVSPEIKMAVELAIRREEVDKYLSKGKPPVATSDKEDSVNDERTEGSDFDDASSSSSSSLASHGSGDATPMPNRFRADTGVDLTHSLLDQTASLKTSSLILLPHKVSPLESRWLDEIVARFPDNAPDFVGNTTEVDSATPIPAKSLKEVWPTYLKYFNGYDALEKIPVREGLKRKLVSQVLTRLGLVTGQSSTELDPREQVLVSFRHW
What is the function of this protein?
Mediates inactivation of the TORC1 complex in response to amino acid starvation.  Required for meiotic nuclear division (By similarity).
What are the official names of this protein?
Nitrogen permease regulator 3, Required for meiotic nuclear division protein 11.
What is the protein family that this protein belongs to?
Belongs to the NPR3 family.
Protein: SYR_PROMA
Sequence: MYNIYKSLNQQVQRALNTAFPEAASQVKESGDFLNPQLVAATKPEFGDFQINGALALARIIKKSPRQIAEILIKQLESNEVFKAICLPPEIAGPGFINLTLQNTCLINEITSRLNDDLLGVPLVNDDEITKKLKPVIVDFSSPNIAKEMHVGHLRSTIIGDSIARILNYRGYKVIRLNHVGDWGTQFGMLITHLKEVAPKALTTANVINLGNLVEFYKKAKQRFDEDEYFQQCSRNEVVNLQRGNKESLKAWELLCEQSRKEFNKIYDRLKIEISERGESFYNPFLQGVIDDLTRSGLLVEDDGAKCVFLNGINGKDGNPLPLIIQKADGGFNYATTDLAAIRYRLKDQPDGDGAGRIIYVTDSGQANHFAGVFQVAKRAKWLPSSSRIEHVPFGLVQGEDGKKLKTRSGETVRLKDLLDEAISRAKLDIERRLNEENRKESQAFIEKVSNTIGIAAVKYADLSQNRITNYQFSFDRMLALQGNTAPYLLYAVVRIAGINRKGGDLHSSVNKLNFSEPQEWRLIRELLKFDEVIIAVEEELLPNRLCNYLFELSQVFNRFYDQIPVLKAEEPSRSCRLALCQLTGDTLKKGLNLLGISTLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_THENN
Sequence: MAKGSKGYIVGVMGPVVDVKFPEEELPDIFNALEVVNPQTGQKIVLEVEQLIGDGVVRTVAMDSTDGLMKGLEVVDTGEPITAPVGKEVLGRILNVIGEPVDEAGEIKSKERWPIHRPAPELIEQSTEIEILETGIKVIDLLAPFPKGGKIGFFGGAGVGKTVLVMELIRNIAIEHKGFSVFAGVGERTREGNELWLEMQESGVLGNTVLVFGQMNEPPGARFRVALTALTIAEYFRDVEGRDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATDMGELQERITSTRRGSITSVQAIYVPADDITDPAPATTFAHLDATVVLSRRIAELGLYPAVDPLDSSSKILDPAVVGREHYEVARGVQEVLQRYKDLQDIIAILGVEELSPEDKLVVHRARRIQRFLSQPFHVAERFTGRPGKYVPLEETIRGFKEILDGKLDDVPEQAFLMAGTIDEVKERAKEMRS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UXAC_LACE2
Sequence: MKQFMDKDFLLSTPTAQHLFHDYAAKMPILDYHCHINPREIAEDRKFENITQVWLGGDHYKWRQMRTNGVDEKYITGDASDREKFQKWAETLEMAIGNPLYHWSHLELQRYFGYNGILNGDTAEEVWNLCNAKLQEDSMSVRNLIKQSNVTLICTTDDPVDSLEWHQVLKDDKTFDVQVLPAWRPDKAMNIEKPEYLDYLETLSNVSGIKVNSFASLIDALKNRMDFFASMGCSVSDHALEYVMYKPYTEEEIEAIFAKRFSGSAITTEEMNKFKTAFMVSVGKEYNKRNWVMQIHYGTIRDNNRFRYDQLGPDTGFDCINTYDCSAEMAQFLNALNATDELPKTIIYSLNPSVNAAIGTVIGCFQDSKAVGKIQQGSAWWFNDHKVGMTNQMTSLANLSLLGNFIGMLTDSRSFLSYTRHEYFRRIMCELIGGWVENGEYPADEKALKKIVEGISYNNAVRYFGFDL
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: GSA_METAC
Sequence: MVSEVTLDKSRQMYEKAKTLIPGGVSSPVRAIKPYPFYTASADGSKIRDLDGNEYIDYCLAYGPAVLGHNHPVIKAAIKEQLDKGWLYGTPTELEVTLAEKVAGYYPSIDMLRFVSTGTEATMSALRLARGFTRKNKFIKIEGGFHGAHDAVLVKAGSGATTLGEPDSLGIPADFTKYTLQAPYNDIETMTTLVEKNRDDLAAVIIEPVLGNIGPILPLPGYLKELRKLTKENDVLLIFDEVITGFRLAMGGAQEYFGVVPDMTTLGKIVGGGLPIGVFGGRREIMEMIAPSGAVYQAGTFSGSPCSVAAGIAVLDYLKKEDIHAKLNSTGDYMRAVVSEIVEDEGLDYTVCGIASMFKIFFGAEPHNYQEALKCDKEGYLSFFHRMLANGVFLPPSQFETNFISAAHSEEDIEKTLEAYVENL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_METBF
Sequence: MAETINKSGRGVNVCKRCGRKQGLVRKYDIYLCRHCFREIAHDMGFEKYS
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: UBX10_HUMAN
Sequence: MATEAPVNIAPPECSTVVSTAVDSLIWQPNSLNMHMIRPKSAKGRTRPSLQKSQGVEVCAHHIPSPPPAIPYELPSSQKPGACAPKSPNQGASDEIPELQQQVPTGASSSLNKYPVLPSINRKNLEEEAVETVAKKASSLQLSSIRALYQDETGTMKTSEEDSRARACAVERKFIVRTKKQGSSRAGNLEEPSDQEPRLLLAVRSPTGQRFVRHFRPTDDLQTIVAVAEQKNKTSYRHCSIETMEVPRRRFSDLTKSLQECRIPHKSVLGISLEDGEGWP
What is the function of this protein?
VCP/p97-binding protein required for ciliogenesis (PubMed:26389662).  Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B (IFT-B) in cilia (PubMed:26389662).  UBX domain-containing proteins act as tethering factors for VCP/p97 and may specify substrate specificity of VCP/p97 (PubMed:26389662).
What are the official names of this protein?
UBX domain-containing protein 10, UBX domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the UBXN10 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Recruited to cilia in a VCP- dependent manner.
Protein: CLC3_ARATH
Sequence: MSSTLSNEESGLGDSNRSTEVDGGDGGNFTAYESRFQSQRFDSSFSNFDSQPEKESDLPCGDSSPRPETQSPPSINSFDDTNDSILPPPSAMEKEEGFALREWRRLNALRLEEKEKEEKEMVQQILEAAEQYKAEFYSKRNVTIENNKKLNREKEKFFLENQEKFYAEADKNNWKAIAELIPREVPVIENRGNKKKTATITVIQGPKPGKPTDLSRMRQVLTKLKHNPPTHMKPKLPSPSGADPNVSVSEQVTVTEKL
What is the function of this protein?
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
What are the official names of this protein?
Clathrin light chain 3.
What is the protein family that this protein belongs to?
Belongs to the clathrin light chain family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Protein: FLGN_ECOLI
Sequence: MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITEQKSSLLATLDYLEQLRRKEPNTANSVDISQRWQEITVKTQQLRQMNQHNGWLLEGQIERNQQALEMLKPHQEPTLYGANGQTSTTHRGGKKISI
What is the function of this protein?
Required for the efficient initiation of filament assembly.
What are the official names of this protein?
Flagella synthesis protein FlgN.
What is the protein family that this protein belongs to?
Belongs to the FlgN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRT_SCHMA
Sequence: MLTSLITSSTTVTLTLSQIYYILDIACGFLISVLVWMNSSVLDNGNHSNPQIRDMSSNMIKADCVVIEDSFRGFPTEYFCTSPRYDECLDYVLIPNGMIKDRLEKMSMDIVDYYEACNATSITLMCVLKGGFKFLADLVDGLERTVRARGIVLPMSVEFVRVKSYVNDVSIHEPILTGLGDPSEYKDKNVLVVEDIIDTGKTITKLISHLDSLSTKSVKVASLLVKRTSPRNDYRPDVGFEVPNRFVVGYALDYNDNFRDLHHICVINEVGQKKFSVPCTSKPV
What is the function of this protein?
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate.  Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.  Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTG25_ARATH
Sequence: MATKITGVFILILTITFSSSSAVTATQQAPSSSPPVLTCTEELVMFSPCLPYVSSPPNNMSETPDPICCSVFTSSVHSSTGNCLCYLLRQPMILGFPLDRSRLISLSQICTDQNSEESFESLCSVSESPELPPLQSIQFTNPFVSGNNVSASPQSVDLAPEVSPSSDLFSPETATLAPPPPPPPLPVLQYFSSDSLKIRNFWFPSTIIMTFATSILARI
What is the function of this protein?
Probable lipid transfer protein.
What are the official names of this protein?
Non-specific lipid transfer protein GPI-anchored 25, AtLTPG-25, Protein LTP-GPI-ANCHORED 25.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: LSPA_BIFLD
Sequence: MTNQQGRLRTRVAVFACVAAAALIVDQLTKAWAMAALSNGQTIRVIPGLLSFTLVRNPGASLGMGSGATWVISLLAVVACVALAVAGVRTVSMKWSVAISFAFAGALGNLIDRVMYADGFLDGKVVDFLNYGWSVGNVADIYLVVAGVVLVILILMGEPFSHKDLIEQSDESLQSEPEADAK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS1_METI4
Sequence: MSGLKLRIGLPKGSLEEATMELFEKAGYIVARSNRAYRPAIDDNELEVRLVRPQEIARYVEQGFLDCGITGKDWILENNADVHIICELKYNKSTSSPVKWVLAVHENSPVRKPSDLQGKWIATEAVNLVKQYLNKIGVEAHVEFSWGATEVKVPELVDAIVDITETGSSLRANHLRIVDTILESFPQFICSHKVWADQEKRRKLSSMALLLQSALNARNKVGLKMNVPKENLSAILKILPSLRNPTVSPLADGQWVAVETILDESKVRDLAPQLKEMGAEGIIEYSLNKIIY
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP2_NEPDI
Sequence: QTVQVEPPYYAGDGEYLMVDLIWTQCEPCTQCFSQDSSSFSTLPCESQYCQDLPSETCDCQYTYGYGDGSSTQGYMAXEDGSSVPNIAFGCGDNLQIDSGTTLTYLPQDAYNAVAQAFTDQINLPTVDESSSGLSTCFQEPSDGSTVQVPEISMQDGGVLNDLQNLAVSFFPTQCGAS
What is the function of this protein?
Extracellular proteinase found in the pitcher fluid of carnivorous plants.  Digest prey for nitrogen uptake.
What are the official names of this protein?
Aspartic proteinase nepenthesin-2, Nepenthesin-II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LAP1_METRA
Sequence: MKLSQVSALAACVPAATARFVELMEADHVVLRPDEPTFLIETAPGKTQWVTEEQKWELRRDGQRFMDITATKDLGSQGLRIKESVEFPKKCVNQDEVKSLAKNLDTAPMKANLEKLSSFHTRYYNSEWGLKSSDWVLEKVNEMIKEAGADKTVTAQSFPHTWKQHSVIATIPGQTNSTIVIGAHQDSINLWLPILAAPGADDDGSGTVTIMEVFRALLKSKDVVQGKAINTIEFHWYSAEEGGLLGSQAIFQQYEKQQRDVKAMLQQDMTGYVKGTLDAGLPESVGVIVDFVHAGLTKFIKTVIEQYCAIPWVETKCGYACSDHASASKAGYPSAFVIESSFDKSDPNIHTTSDLIEHLSFDHMLQHAHMTLGFVYELGFHNFAKAVEGDGEL
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAA_HAES1
Sequence: MTNIHHHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPTGIILSGGPESTTEANSPRAPEYVFNAGVPVLGICYGMQTMAMQLGGLTETSTHREFGYAEVSLRNPTALFDHLNDDATTSQTTLDVWMSHGDKVTRLPDNFQITGMTSTCPIAAMSDESRRFYGVQFHPEVTHTKCGQKLLQNFVVDICGCETNWTAENIIEDAVARIKAQVGGDEVILGLSGGVDSSVTALLLHRAIGKNLHCVFVDNGLLRLNEGDQVMEMFGDKFGLNIIRVEAEDRFLEALKGIDEPEAKRKTIGKVFVDVFDDEAKKLTDVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMLNRHPFPGPGLGVRVLGEIKKEYCDLLRKADAIFIEELHKADWYYKVSQAFSVFLPVKSVGVMGDGRKYDWVISLRAVETIDFMTAHWANLPYDLLGKISNRIINEVNSISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: XG74_PAESP
Sequence: MKTFLGKKLWMASLAVALAAGSFAALPEMTSAAPSEPYTWKNVVTGAGGGFVPGIIFNESEKDLIYARTDIGGAYRWNPANESWIPLTDFVGWDDWNKNGVDALATDPVDPDRVYLAVGTYTNSWDKNNGAILRSTDRGDTWQTTTLPFKVGGNMPGRSMGERLVVDPNDNRILYFGARSGNGLWRSSDYGATWSKVTSFPNPGTYVQDPANEYGSDIVGLAWITFDKSSGQVGQATQTIYVGVADTAQSIYRSTDGGATWTAVPGQPTGYLPHHGVLDADGSLYITYSNGVGPYDGTKGDVWKLNTSTGAWTNISPIPSSSADNYFGYGGLAVDAQEPGTLMVATLNSWWPDAILFRSKDGGTTWTRIWEFDGYPNRKFRYTQNISAAPWLTFGTTPAPPEVSPKLGWMIGDLEIDPFDSDRMMYGTGATIYGTNNLTNWDNNEKIDISVMAKGVEEMAVLDLVSPPSGAHLVSGLGDVNGFRHDDLDQPPAKMFSSPNYASTESLDFAELNPSTMVRVGKADYAADPNAKSIGLSSDGGTNWYKANAEPAGTAGGGTVAISSDGSKLVWSTSDKGVHYSSTGGNSWTASTGIPAQAKVISDRVNPNKFYGFAAGKIYVSVNGGVSFSQTAAAGLPVDGNADLDAVPGVEGELWFAGGNEDGGPYGLWHSTDSGASFAKLSNVEEADSIGFGKAAPGRNSAALYAVAQIDGTRGFFRSDDGGASWVRINDDAHQYARVTTITGDPRIYGRVYLGTNGRGILYADPVGGNNGGETPPVSHSGISPQSTEFDLNADRQADIPVALTLNGNTLASIRNGNHVLVQGSDYTMSGSQVFLSKTYLATLSKGVQSLVFRFSAGNDATLSITVKDTTQVPLPEGSIRIEMYNGTTSATANSINPKFKLTNTGTAPLQLADVNIRYYYTIDGEKPLNFFCDWATAGSANVTGTFSALPAAVNGADHVLEIGFTASAGTLAAGQSTEVQVRFSKTDWTNFTQTDDYSFAASSTAYENWSKVTGYVSGTLQWGIEP
What is the function of this protein?
Hydrolyzes the glucosidic bonds of unbranched Glc residues in tamarind seed xyloglucan, producing XXXG, XLXG, XXLG and XLLG.  May have a dual endo- and exo- mode of action towards xyloglucan, or may have an endo-processive mode of action.
What are the official names of this protein?
Xyloglucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 74 family.
Protein: SEC7A_SCHPO
Sequence: MTDLEIETVSRVSSNPDEVKGSSVVEEEPDSESTIKSRVSDEIDEHDSIPEQSNTEKSIEINDKNLEAEKDIESNLSLRPPEDDLDSRSIESEQTGTLSKQTTSTSEAPQDLKIWKNISNASNQNSGKLNPQLFVIEAFKHMSKAKATKRHKKLREAINNVQIELQKQPFLLPEVILEPLVMACQTNSTTLLTITLDCFAKLIDYNYFDSPTLNPSDITLMERVVNTIASCFCGESTPERVQLQIVKALLAAITSERTIIRHSFLLTAVRQTYNIFLLCKDSTTQAIAQVALLQMVDSVFQRLSTVLNHEREFSTINMNKSSSNGTPDRANSPIPSQLSENKLTLESFEHRKSFDQVREEAPLEEDSLEQQLLRDAFLLIRALCKLSIKNIPYEHEYDLKSQSMRSKLMSLHLIYHILRTYMNILSDINVKIRSPTSTPTPLIDAVKQYICLALAKNVVSHVLPVFEISCEIFWLILSELKNFFKSELEVFFTEIFFPILEMRTSSNQQKIVLLNIFHRMCEEPQTLIELYLNYDCISGNTENIYERAIVTLSRIASQSTSDPPPSFVFRDDQLVIDKPGFVYHTLNDIPQLNSSTIGSYVHSHNPPYFDYQIRLKSYRCLISTLSSLFTWCNQTFAPTVEITAKDDETESTSKGEEPQKSKSEPPSAGINSTSMDNLESSGQALATDDPSQFENLKHRKKQLQEAIQKFNYKPKEGIKILLSSHFIASKTPTDIAKFLISTEGLDKAVLGEYLGEGNDENIAIMHSFVDHMSFNDIPFVNALRSFLQKFRLPGEAQKIDRFMLKFAEKYIDDNLGVFKNADTAYILAYSIIMLNTDLHSPQVKNRMTCQDFIKNNRGVDDGANLSDSFLTEVYEEIQKNEIVLKDEQDPTSNFPEIPGTSNLSFAANISNALATVGRDLQREAYYMASNKMANKTEALFKDLIREQRERGKLSGNDIYYTARHFEHVCPMFEAVWMPILAAFSEPLQLSSDPALIQLSLDGFRLAMNVIFFFSMDLPRNAFMQTLTKFTHLNNTSELKWTNMHALKTLLEISLAHGDKLRDSWKDVLLCISQLERVQLISAGVDINSLPDVSTTKPLRKSLDKNIRQSRSGSISLKHSKSFQSASTHSTKSSSVEIVREYSSREVVMAVDMLFSNTRNLGSEGIYDFVKALIEVSWEEIECSLELSNPRLFSLQKLVEISYYNMRRIRMEWSSIWSLLGTYFTQVSCHENSIIASFALDSLRQFSMQFLEIEELSHFKFQKDFLQPFSHAMENSQDLKIKDLVLRCIDQMIKARYQNIRSGWRTIFHILAYASKIENLLVLQCAISVVSSLGHEHISCVLTQGAYIDLISCITKFAKLNGNQKFCLSCVDMLKNLEHELIKHLKHMKKESVYSKKLEEEYWLPFLLSFNEIICEASDLEVRSKALKVLFDCLYRHADDFDEEFWETVSNKALLSIFSILSITNSQRLYLAKNTEETEVWMLTTMVEALKAFIELIKNLFERLHFLLPKALNLLEKCICQENSMISKVGLSCFSQFVLKNKNQFKDVDWDEIINSINQLLQMTLPIELRDPSLYPQVNSDSSLEDVKENSFRPHEISRFNSQSVFKSKKHHLKSIVVKCTLQLLMLNCLWELFHSDNMLTNIPKRKMVKLLDILKQSWEFAESFNSDFEIRAKILSSGIVEHMPNLLSQEALCAKLYFYTAFECMSSLKSDSHDTEEYNDLMDVFQKKIYLASQLVLHGFQRVIGDNPVKGVAAFQPVIAALVSYINSLDEIQFSRGKSEFYQLLCAIVACGHIDQQLGTSLSNAFLRYAC
What is the function of this protein?
May play a role in protein transport.
What are the official names of this protein?
Protein transport protein sec71.
Protein: MURD_STAAR
Sequence: MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVVSGSHPLTLLDKNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTNGKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKPHIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLYFSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIIDSLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFDELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSPACASWDQYSTFEERGEKFIERFRAHLPSY
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FS2P1_HUMAN
Sequence: MKFEEKCGDNGSIVGRNQSYPGEKHQPKGKPIANGEAEVYAKQEANGKCSTPRKSLSMYTWLEIQRHNHEADQLVINCKVYNVSSWADRHPGGHQVLNHCAGEDAMDVFRAMHPELDIVQLYLKPLLIGELAPGEPSQERHKNSQLVKDFQELWSIAEAMNMFHANLGFFFLHFVQILILEVLAWLIVYHFGSGWPVTMFISFLLTISQASSSFLQHDAGHLSIFRKSKWNHVVHKFVMCHLKGLSADRWNYWHFEQHVKPNIYPKDPDIDTDPLFLLGDSQPVKYGKKKIKYINYEEQHLYFYKVWLPLFMPVYLKLPSMQAMYLQRYWVCFSLQDITWVSSFYIYFITFGLYYGIFGTMLLIYLVKFLESPWIVYVTQMSHITMRMSTEENRDWLTTQVLATCNTESFFNDFTGHLNFQIEHHLFPTMPRHNYHKVAPLVRSLCAKHGLHYVNKPMLRAFGDIVRALKKSAALWADAYYE
What are the official names of this protein?
Putative fatty acid desaturase 2-like protein FADS2B, Fatty acid desaturase 2 pseudogene 1, Fatty acid desaturase 2B, pseudogene.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PSTB_METTH
Sequence: MICMYRIEVEDLNVYFDEAHILKDINLKIPKNTVTALIGPSGCGKSTFIRTLNRMNDVISGFRHEGHVYLDGKDIYDPDMDVVELRKKVGMVFQKPNPFPKSIFENVAYGLRVHGYDDRDFIEERVEESLRAAALWDEVKDKLDKSALGLSGGQQQRLCIARTIAIEPEVILMDEPCSALDPISTTKIEDLIHKLKNDYTIIIVTHNMQQATRVSKYTAFFLHGEIVESGLTEQIFIEPRDKRTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ELYS_HALFU
Sequence: MKLLVLWVFAMMATVAMSRRWTFVRYHYINKAYEVTMKIQIISGFDRQLTAWLRVHGRRLTNNQKKTLFFVNRRYMQTHWQNYMLWVKRKIKALGRPAAVGDYTRLGAEIGRRVDMVFFYNFLSGRKMIPPYSAYMAKLNALRPADVPVKNHGK
What is the function of this protein?
Creates a 3 um hole in the egg vitelline layer through which the sperm passes.  Does not have enzyme activity (By similarity).  Species-specific interaction between the sperm protein lysin and the egg protein VERL exposes a basic surface on lysin that may dissociate the egg vitelline layer via electrostatic repulsion.  Plays a role in ensuring species-specific fertilization (PubMed:10698629).
What are the official names of this protein?
Egg-lysin, Sperm-lysin.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome lumen.