PharMolix/UniProtQA huggingface dataset:
Protein: H3L1_LILLO
Sequence: MARPRKEAPQRNLDRDENARQQPTEEPQDEAPRNQGRQQQQQRPPAAPRRPRRFRPGTVALREIRRIQRSNVPLIPHSPFMRLVRELAAEFLDDCRFAAETFIMLKEVVEDELVNHFGNVQICSIHAKRIIITVKDFKLAKLLKGEPED
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
What are the official names of this protein?
Histone H3-like 1, Generative cell-specific histone H3, Histone gH3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Distributed throughout the chromatin.
Protein: PHF10_XENLA
Sequence: MAAVVSAKPLCDSEPAIPAPPSVKEDNSNDTKDPEENSNDGSQPAKRRRMSGDSTPSCENSNQDFGSSYFPAENVIEYKWPPDETGEYYMLQEQVSEYLGVTSFKRKYPDLERRDLSHKEKLYLRELNVITETQCTLGLTALRSDEVIDLMIKEYPAKHAEYSVILQEKERQRITDHYKEYSQLQQQNTQKVEAGKVPEYIKKAAKKAAEFNSNLNRERMEERRAYFDLQTHIIQVPQGKYKILPSEMTKVSPYPVSLIPGQFQEYYKRYSPNELRYLPLNTALYEPPLDPLDPELLALDSDGDSDEVEEMKSEKKKTKGSSVRLSIDSSSMNMSESDNTQDTQEETPQPRPKVKEKSSTPRKEGSKRSVLSKSVSGYKPKSIPNAICGICLKGKDANKKGRSERLIHCSQCDNSGHPSCLDMSAELVAVIKKYPWQCMECKTCIICGQPHHEEEMMFCDTCDRGYHTFCVGLGALPSGRWICDCCQKVPATPKKGARKVKNSKEG
What is the function of this protein?
Involved in transcription activity regulation by chromatin remodeling in the context of the neural progenitors-specific chromatin remodeling complex (npBAF complex).  May play a role in the proliferation of neural progenitors (By similarity).
What are the official names of this protein?
PHD finger protein 10.
What is the protein family that this protein belongs to?
Belongs to the SAYP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL11_POLNA
Sequence: MAKKIVGFVKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAQTQGVEPGLPLPVVITAYADKSFTFIIKTPPAITLIKKAIKLDKGSATPHSAKVGKITRAQLEEIAKAKMKDLTAADLDAAVRTIAGSARSMGVTVEGVV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: VP05_OPICY
Sequence: LGKSVTN
What are the official names of this protein?
Venom peptide Ocy5.
What are the subcellular locations of this protein?
Secreted.
Protein: RL33_MANSM
Sequence: MAAKGAREKIRLVSSAETGHFYTTDKNKRNMPEKMEIKKFDPVVRKHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ORF6_HAPV1
Sequence: MNKKSLLVVLVIALAVVPFAATAQTTPGQNQTAPNSSSPTVISQVDSITAITDYELRDGDLWIQFQSSGGNTLSITETAGSEGATQVRVRSVDIPRGTSTVTIDLFNSADGSVLITSRLSLEQNSGTVVSVSGGSAIISGPFTASDAQASGLGAAISVASVTLLLVFRASRGESTEGERIA
What are the official names of this protein?
Uncharacterized protein 6.
Protein: Y5570_STRGG
Sequence: MTENTHETAPNTADTDTADFDTADTDRADGAADVSTNTPNETGEAAIPELVIISGMSGAGRSTAAKCLEDLGWFVVDNLPPALIPTMVELGARSQGNVARIAVVVDVRGRRFFDNLRESLADLEAKHVTRRIVFLESSDDALVRRFESVRRPHPLQGDGRIVDGIAAERDLLRELRGDADLVIDTSSLNVHELRAKMDAQFAGESEPELRATVMSFGYKYGLPVDADLVVDCRFLPNPHWVPELRPFTGVNEEVSDYVFDQPGAKEFLNQYTELLQLIAAGYRREGKRYVTIAVGCTGGKHRSVAMSEKLSARLAAEGIETVLVHRDMGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SGR_5570.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: NHAA_HELPY
Sequence: MNLKKTENALSLTLKNFIKSESFGGIFLFLNAVLAMVVANSFLKESYFALWHTPFGFQIGDFFIGFSLHNWIDDVLMALFFLMIGLEIKRELLFGELSSFKKASFPVIAAIGGMIAPGLIYFFLNANTPSQHGFGIPMATDIAFALGVIMLLGKRVPTALKVFLITLAVADDLGAIVVIALFYTTNLKFAWLLGALGVVLVLAVLNRLNMRSLIPYLLLGVLLWFCVHQSGIHATIAAVILAFMIPVKIPKDSKNVELLELGKRYAETSSGALLSKEQQEILHSIEEKASALQSPLERLEHFLAPISGYFIMPLFAFANAGVSVDSSINLEVDKVLLGVILGLCLGKPLGIFLITFISEKLKITARPKGISWWHILGAGLLAGIGFTMSMFISNLAFTSEHKDAMEVAKIAILLGSLISGIIGALYLFALDKRAALKK
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_ALIF1
Sequence: MLQPKRTKFRKVMTGRNRGLAKGTEVSFGDFGLKAVGRGRLTARQIEAARRAMTRHIKRQGQIWIRVFPDKPITEKPLEVRQGKGKGNVEYWVAQIQPGKVMYEMNGVPEELAREAFRLAARKLPIKTTFVTKQVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: NRDR_EHRRG
Sequence: MKCPFCNNISTNVKDSRSIEDDMLIRRRRVCPVCNSRFTTTEKLLLRSLMVIKKNGGLEQFDKKKLLSSILIATKKRPVSHDKINMMVNNIFYELEGKKDNAIPTDVIGKMVMDNLFKLDKVAYVRFASVYMNFKNINDFSNIIAKIINENNL
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: HIS1_STAA2
Sequence: MLRIAIAKGRLMDSLINYLDVIEYTTLSETLKNRERQLLLSVDNIECILVKGSDVPIYVEQGMADIGIVGSDILDERQYNVNNLLNMPFGACHFAVAAKPETTNYRKIATSYVHTAETYFKSKGIDVELIKLNGSVELACVVDMVDGIVDIVQTGTTLKANGLVEKQHISDINARLITNKAAYFKKSQLIEQFIRSLEVSIANA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_BPSAV
Sequence: MTKKLVTEEMRKQWLPVLQKESEAIQPLSAENVTIRLMQNQAEWNAKNLGESDAPGSVNSTVGKWQPVLIDMAKRLAPINIAMDFFGVQPLSGPDGQIFALRARQGVGDGSTTAQARKELFMNEADSGYSGDGTVQAGDPSGFSQAEIEGSGSVVTTIGKGMPSTDAELLGTTTNPWARVGITVQKATVTAKSRGLYADYSHELRQDMMAIHGEDVDNILSDVMVTEIQAEMNREFIRTMNFSAVRFKKFGTNGVVDIAQDISGRWALEKWKFLTFMLEVEANGIGVDTRRGKGNRVLCSPNVASALAMSGMLDYAPVLQENTKLAVDPTGQTFAGVLSNGMRVYVDPYAVAEYITLAYKGATALDAGIFFAPYVPLEMYRTQGETTFSPRMAFKTRYGICANPFVQIPANQDPQVYVTADGIAQDSNPYFRKGLIKSLF
What is the function of this protein?
Major capsid protein that self-associates to form the icosahedral capsid.
What are the official names of this protein?
Major capsid protein, Major head protein.
What is the protein family that this protein belongs to?
Belongs to the T4 phage major capsid protein family.
What are the subcellular locations of this protein?
Virion. Note=Forms the capsid icosahedric shell.
Protein: AROA_SHELP
Sequence: MKQLRLNPISKVHGTVNIPGSKSISNRALLLATLAEGKTRLTNLLDSDDIRHMLTALKQLGVNYQLSDNNRVCEVEGLSGVINSDTAQTLFLGNAGTAMRPLCAALTLGSGEFTLTGEPRMEERPIGDLVDALNALGADIRYLKQPGFPPLTINATGLNGGDVEIAGDLSSQFLTALLMVTPLAKAQVNIKIKGELVSKPYIDITIALMAQFGVTVINHDYQRFEIPAGQKYVSPGTVLVEGDASSASYFLAAGAIQGGEVKVTGVGLKSIQGDVKFAEVLEAMGAQIEWGDDFIIARSAPLHGVDLDMNHIPDAAMTIATAALFATGTTTLRNIYNWRIKETDRLAAMATELRKVGAEVEEGHDYIRVTAPAQLNTADIDTYNDHRMAMCFSLMAFADCGITINDPDCTSKTFPDYFAQFAALAQ
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFH5_BOTFB
Sequence: MGYKNSVRKILGNIFKPKILKAKRQGAEGQLNVVQRPRSVIFLKAGVRLSRTPDTCVQNIAKERCDKVIGDKIPYGPSNQASSFAGQLGLKREKEINEEVGGWTKVVYKVEADLVEKEEEKAGLAGWDGLGFESNTKMSAEPNNNQAKADVPEEVVEPKPTTVEEPKSTTVEEPKSTTVEESKSTTVEEPKSTTAEQPKSTIEQDPKPSTTESSPVQIDDSTPIPQITTEEPKPTVAEPSTTESVTAEPTTEQPQEAAVKLESVKEADAEAAAKLEATKDADVEKAASTSQHSVSFDKATKTHDGSPLSKFYSELPAILEAAEYNEMWGIVLDPSETHVQTSIVLEKFLRANAKDVPKAKAQLIEALKWRKTMQPQKLLESTEFDKVKFGNLGYVTSYNTTEGGKEVITWNIYGAVKDVKKTFSDVPEFLKWRAALMELSIKELDLASATEKIPENGPDPYRMIQVHDYLNVSFLRMDPSIRAASKETIQTFSMAYPELLKEKFFVNVPLVMGWVFTAMKIFLSADTIKKFHPLSYGSNLGSEIPNVAEQLPKEYGGKGGELKSGLTVKYSEGEASKTA
What is the function of this protein?
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity.  Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.  Heme-binding protein that may play a role in organic oxidant-induced stress responses.
What are the official names of this protein?
Phosphatidylinositol transfer protein sfh5, PITP sfh5.
What is the protein family that this protein belongs to?
Belongs to the SFH5 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: OMPA_RICRI
Sequence: MANISPKLFKKAIQQGLKAALFTTSTAAIMLSSSGALGVATGVIATNNNAAFSNNVGNNNWNEITAAGVANGTPAGGPQNNWAFTYGGDYTVTADAADRIIKAINVAGTTPVGLNITQNTVVGSIITKGNLLPVTLNAGKSLTLNGNNAVAANHGFDAPADNYTGLGNIALGGANAALIIQSAAPSKITLAGNIDGGGIITVKTDAAINGTIGNTNALATVNVGAGTATLGGAVIKATTTKLTNAASVLTLTNANAVLTGAIDNTTGGDNVGVLNLNGALSQVTGDIGNTNSLATISVGAGTATLGGAVIKATTTKLTDAASAVKFTNPVVVTGAIDNTGNANNGIVTFTGNSTVTGNVGNTNALATVNVGAGLLQVQGGVVKANTINLTDNASAVTFTNPVVVTGAIDNTGNANNGIVTFTGNSTVTGDIGNTNALATVNVGAGTATLGGAVIKATTTKLTNAASVLTLTNANAVLTGAIDNTTGGDNVGVLNLNGALSQVTGNIGNTNSLATISVGAGTATLGGAVIKATTTKLTDAASAVKFTNPVVVTGAIDNTGNANNGIVTFTGNSTVTGDIGNTNSLATISVGAGTATLGGAVIKATTTKLTNAASVLTLTNANAVLTGAIDNTTGGDNVGVLNLNGALSQVTGDIGNTNSLATISVGAGTATLGGAVIKATTTKITNAVSAVKFTNPVVVTGAIDSTGNANNGIVTFTGNSTVTGDIGNTNALATVNVGAGTATLGGAVIKATTTKLTNAASVLTLTNANAVLTGAIDNTTGGDNVGVLNLNGALSQVTGDIGNTNSLATISVGAGTATLGGAVIKATTTKLTNAASVLTLTNANAVLTGAVDNTTGGDNVGVLNLNGALSQVTGDIGNTNSLATISVGAGTATLGGAVIKATTTKLTNAASVLTLTNANAVLTGAIDNTTGGDNVGVLNLNGALSQVTGDIGNTNSLATISVGAGTATLGGAVIKATTTKLTDAASAVKFTNPVVVTGAIDNTGNANNGIVTFTGNSTVTGNVGNTNALATVNVGAGLLQVQGGVVKANTINLTDNASAVTFTNPVVVTGAIDNTGNANNGIVTFTGNSTVTGNVGNTNALATVNVGAGLLQVQGGVVKANTINLTDNASAVTFTNPVVVTGAIDNTGNANNGIVTFTGNSTVTGDIGNTNALATVNVGAGITLQAGGSLAANNIDFGARSTLEFNGPLDGGGKAIPYYFKGAIANGNNAILNVNTKLLTASHLTIGTVAEINIGAGNLFTIDASVGDVTILNAQNINFRARDSVLVLSNLTGVGVNNILLAADLVAPGADEGTVVFNGGVNGLNVGSNVAGTARNIGDGGGNKFNTLLIYNAVTITDDVNLEGIQNVLINKNADFTSSTAFNAGAIQINDATYTIDANNGNLNIPAGNIQFAHADAQLVLQNSSGNDRTITLGANIDPDNDDEGIVILNSVTAGKKLTIAGGKTFGGAHKLQTILFKGAGDCSTAGTTFNTTNIVLDITGQLELGATTANVVLFNDAVQLTQTGNIGGFLDFNAKNGMVTLNNNVNVAGAVQNTGGTNNGTLIVLGASNLNRVNGIAMLKVGAGNVTIAKGGKVKIGEIQGTGTNTLTLPAHFNLTGSINKTGGQALKLNFMNGGSVSGVVGTAANSVGDITTAGATSFASSVNAKGTATLGGTTSFANTFTNTGAVTLAKGSITSFAKNVTATSFVANSATINFSNSLAFNSNITGGGTTLTLGANQVTYTGTGSFTDTLTLNTTFDGAAKSGGNILIKSGSTLDLSGVSTLALVVTATNFDMNNISPDTKYTVISAETAGGLKPTSKENVKITINNDNRFVDFTFDASTLTLFAEDIAADVIDGDFAPGGPLANIPNAANIKKSLELMEDAPNGSDARQAFNNFGLMTPLQEADATTHLIQDVVKPSDTIAAVNNQVVASNISSNITALNARMDKVQSGNKGPVSSGDEDMDAKFGAWISPFVGNATQKMCNSISGYKSDTTGGTIGFDGFVSDDLALGLAYTRADTDIKLKNNKTGDKNKVESNIYSLYGLYNVPYENLFVEAIASYSDNKIRSKSRRVIATTLETVGYQTANGKYKSESYTGQLMAGYTYMMPENINLTPLAGLRYSTIKDKGYKETGTTYQNLTVKGKNYNTFDGLLGAKVSSNINVNEIVLTPELYAMVDYAFKNKVSAIDARLQGMTAPLPTNSFKQSKTSFDVGVGVTAKHKMMEYRINYDTNIGSKYFAQQGSVKVRVNF
What is the function of this protein?
Elicits protective immunity.
What are the official names of this protein?
Outer membrane protein A, 190 kDa antigen, Cell surface antigen, rOmp A, rOmpA.
What is the protein family that this protein belongs to?
Belongs to the rickettsiae OmpA/OmpB family.
What are the subcellular locations of this protein?
[Outer membrane protein A]: Periplasm. SUBCELLULAR LOCATION: [120 kDa surface-exposed protein]: Secreted. Cell surface. Note=Surface exposed. This bacterium is covered by a S-layer with hexagonal symmetry. SUBCELLULAR LOCATION: [32 kDa beta peptide]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: RABEK_MOUSE
Sequence: MRGLRQGIMKQLPILEPGDKPRKATWYTLTCPGDRPCPRVGHSCSYFPPVGDAESGKIFIVGGANPNQSFSDVHTMDLGTHQWDTATREGLLPRYEHASFLPSCSPHSIWVFGGADQSGNRNCLQVMSPEDRTWSTPEVTGSPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVEDVKLHVFDANTLTWSQPETHGSPPSPRHGHVMVAAGTKLFIHGGLAGDKFFDDLHCIDIGDMSWQKLGPTGAVPVGCAAHAAVAVGHHVYMFGGMTATGALNMMYKYHTEKQHWTVLQFDTSLPAGRLDHSMCVIPWPVMSTSENKDSDSVILTLQDEKGDAAEKAETQSGGPHEESPTTVLLCFVFGGMNTEGEVYDDCLVTVVD
What is the function of this protein?
Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
What are the official names of this protein?
Rab9 effector protein with kelch motifs.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane. Note=Interaction with PIKFYVE and subsequent phosphorylation recruits it to the endosomal membrane.
Protein: VATG_CAEBR
Sequence: MASQTQGIQQLLAAEKRAAEKINEARKRKLQRTKQAKQEAQAEVEKYKQQREQEFKGFEQQYLGTKEDIESKIRRDTEDQINGMKQSVASNKQAVIVRLLQLVCDIKPELHHNLTLQKKLHGQFAA
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.  In neurons, required for necrotic cell death by promoting intracellular acidification (By similarity).
What are the official names of this protein?
Probable V-type proton ATPase subunit G, V-ATPase subunit G, Vacuolar proton pump subunit G.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase G subunit family.
Protein: PGLR_ACTDE
Sequence: MALQRRFFQFVIITLLIPSFILGYTSAVHEDPPHDYHLEEYGYDFKAYPSYITTIGDNDFGSSMSHENGIFGLRKVDYGMDRVLDASKTVNVDDFGAKGDGRDDTKAFEKAWKAACSSTSSAVLLVPKKNYLVRPISFSGPCKSGLTMQIYGTIEASDDRSDYRKDGRHWLVFDSVQNLRVEGGGTINGNGKIWWQNSCKTNKALPCKDAPTALTFYKSKHVIVKNLKIENAQQIHVSFDNCVNVQASNLMVTAPENSPNTDGIHVTGTQNIHISSCVIGTGDDCISIVNGSRKVRVNDITCGPGHGISIGSLGYGNSEAHVSDVVVNGAKLCGTTNGVRIKTWQGGSGSASNIKFQNVEMHNVENPIIIDQNYCDQDKPCQEQSSAVQVKNVVYQNIKGTCASNVAITFDCSKRFPCQGIVLEDVDLEIEGGAAAKALCNNVELSETGVVSPHCQEEGGEEEEEAS
What is the function of this protein?
Acts in concert with the pectinesterase, in the ripening process.  Is involved in cell wall metabolism, specifically in polyuronide degradation.
What are the official names of this protein?
Polygalacturonase, PG, Pectinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: PUR7_STRP4
Sequence: MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAGKGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSKRFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINELLKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLGELTDVYEIVWEKLQGLK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: CBID_BURO1
Sequence: MRDETPEQPAPLRFGYTTGSCATATSLAAARLLLAGQADDAVEIVLPKGQRVMMRLEFCRATADGAEAGTIKDAGDDPDVTHGALIFARVALAAAPGVRFHAGPGVGTVTRAGLTLPVGEPAINPVPRQMMTTHLEALAAEHGYAGGFDVTIGVEGGEALALKTMNPRLGIVGGLSILGTTGIVRPFSCSAYIASIHQGIDVARANGIAHIAACTGNASEDAMRAHYQLPDMALIEMGDFAGAVLKHLRRAPVARLSMCGGFGKLSKLAAGHLDLHSRHSSIDLPLLAQWAAEAGANEALQAAMRAANTSQEALKLAQADGVPLGDLVCAHALRVARDIVPPSVAVEMFAIDRQGRFVGAAR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: B2I2_SICPE
Sequence: WIMGHMVNAIEQVDEFLDLGANAIEFDVDFDDDGVAKYTHHGIPCDCGRLCTKYAVFTEYLDYVRQVTTPGDPKFRKELVLLALDLKLQRISSEKAYAAGVDVATKLLDHYWMRGWNGGRAYILLNIPLVEDYEFIRAFKDTLRKEGHEQYNAKVGINFTGNEDLDEIREVLEKLGEDEHIWQADGITSCFPRGTERLKKALEKRDTPGYKYISKVYAWTLVRSSIMRRSLRLGVDGVMSNYPDRVVKVLKEKEFSDKFRLATYADNPWEKFTPI
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin SpeSicTox-betaIIA2ii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGE_SALNS
Sequence: MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFSDLGFNVEVQPVPGTRNKFNMLASTGHGAGGLLLTGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTALRPDCAIIGEPTSLQPIRAHKGHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQLRDSLKARYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLNDALAPVSERWPGRLTVAELHPPIPGYECPPDHQLVEVVEKLLGTKTDVVNYCTEAPFMQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVVHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_LEGPA
Sequence: MNNKTNWVIIGRFGRPHGIKGFVTVHSFTDPADNILRYNDWHVFLNKQWQPLKLLTIEVRSKAIIAQIEGYPERELVSALTNLDIGVQESQLAALAPGEYYWYQLIGMSVINSKGDLFGKVVEIMPTGSNDVLVVEGEKRHLIPYLPGQFVINIDESQQVITVDWDMNF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_SPHAL
Sequence: MSDEQDKPTLSRKPLGLKRTVEAGQVQQQFSHGRRNTVVVEVKRRRVLGRPGEAAPTPEVEEAKAAPAPAPAPAAPRPAAPKPAAVDSLMTRQERQAQLLREAEEARMAALEENRRREEAERARAAEEERARAEKREEQAATKAPEPAPTPAASAPDATAADAPPAAEGPVETAARPATASAAPAPRRFTPVEALKRPEPKRPEPKASRGGENRRQSGKLTVTRALNEDEGARARSLAALKRAREKEKRSHMTSSGPREKQVREVVVPDTITVQELANRMAEKGADLVKALFKMGMPVTVNQTIDQDTAELLVTEFGHEIKRVSEADIDIRHDEDVDDAAQLKPRAPVVTIMGHVDHGKTSLLDALRGANVQAGEAGGITQHIGAYQVKAKDGSVITFLDTPGHEAFTEMRQRGANVTDIVILVVAADDGLKPQSIEAINHAKAAGVPIIVAINKVDKEGANPQRVRERLLEHELVVEEMGGDVQNVEVSALKKTGLDKLLDAIALQAEIMELKANPDRAAEGTVIEAKLDKGRGPVATILVRRGTLKVGDIFVCGAESGRVRALVDDHGKQVKQATPSMPVEVLGLGGVPMAGDTLIVVENEARAREVAAYRQEQALKKRTAQAPVSLEGMFSALADKANVIEYPVVIKGDVQGSVEAIVNALNKLSTDEIRVRVLHAGAGAITESDVTLAASTRAPIIGFNVRPNAKAREIANREKVRFLYYDVIYHLTADVAKEMAGELGPERIENVVGRAEVKDVFPAGKRDKAAGLLVLEGSIRKGLHARLTRDDVIVSATTIASLRRFKDDVAEVRAGLECGVVLADTNDIKPGDHLEVFEVELRERTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_PROMP
Sequence: MEKDSSIKKSRAIRRLVIWYKRNSAVTSIVDTAANSAVTASNVAGNVVSGAGSVVSTASNVAGNVAGNVVSSAESVVNTASNVVSSASSIAKNTLQPLVFDPLKRLQNSDNLISKEEVPNSERIWIAVDGMGGDYAPVPILEGCLGAISRFPINIKFVGKIEKVRYEAERVGLIDLLEKEIDNNRLELIDSGDPIGMNEEATAVRKRKDASINVAMDLVKTNKAKAVYSAGNSGALMASAIFRIGRLKGIERPAIGALFPTRDQTRPVLVLDVGANTDCKPSYLHQFALLGNVYAKDVLQIEKPRIGLLNIGEEECKGNDLSIKTFELLSNEKSFNFGGNCEGRDVLSGDFDVVVCDGFTGNILLKFLESVGGVLLDILRSELPRGRRGKVGSAFLKSNLLRIKKRLDHAEHGGALLLGVNGICVIGHGSSKSLSVVSALRLAHSAVNHNVMENLNQLQKLQVLNS
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity).
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MATP_ECO8A
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVLLSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQRLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKHDLQALLGKE
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSAP_SALTI
Sequence: MRITKVEGSLGLPCQSYQDDNEAEAERMDFEQLMHQALPIGENNPPAALNKNVVFTQRYRVSGGYLDGVECEVCESGGLIQLRINVPHHEIYRSMKALKQWLESQLLHMGYIISLEIFYVKNSE
What are the official names of this protein?
Secretion system apparatus protein SsaP.