PharMolix/UniProtQA huggingface dataset:
Protein: PTN21_MOUSE
Sequence: MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELREVTYFSLWYYNKQNQRRWVDLEKPLKKQLDKHALEPTVYFGVLFYVPSVSQLQQEITRYQYYLQLKKDILEGNLPCTLEHAIQLAGLAVQADFGDFDQYESQDFLQKFALLPVAWLQDEKVLEEAAQKVALLHQKYRGLTAPEAELLYMQEVERMDGYGEESYPAKDSQGSDISIGACLDGIFVKHKNGRPPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYVWRLCVARHKFYRLNQCSLQTQAATLNSVRRDSSSRMSLPKPQPYAMPPPPQLHYNGHYTEPFASSQDNIFVPNKNGFYCHSQTSLDRTQIDLSGRIRNGSVYSAHSTNSLNTLQPYLQPSPMSSNPSITGSDVMRPDSLPSHRHSALIPPSYRPTPDYETVMKQLNRGMVHADRHSHSLRNLNIGSSYAYSRPDALVYSQPEIREHPHLTSPQSAHYPFNLNYSFHSQSPYPYPAERRPVVGAVSVPELTNVQLQAQDYPAPNIMRTQVYRPPPPYPYPRPANSTPDLSRHLYISSSNPDLITRRVHHSVQTFQEDSLPVAHSLQEVSEPLTAARHAHLQKRNSIEIAGLTHGFEGLRLKERTVSASAADVAPRTFSAGSQSSVFSDKMKQEGTEEQEGGRYSHKKSLSDATMLIDSSEEDEDLEEDSSREQAISAVSEPRLTAAFSQELNYPCASATPITGPLHIFEPKPHVTEPEKRAKDISPVHLVVETHRPRRDGLLTPSMSESDLTTSGRYRARRDSVKKRPVSDLLSGKKSAVEGLPPLGGMKKTRADAKKIGPLKLAALNGLSLSRLPLPDEGKEVSTRATNDERCKVLEQRLEQGMVFTEYERILKKRLVDGECSTARLPENAERNRFQDVLPYDDARVELVPTKENNTGYINASHIKVSVSGIEWDYIATQGPLQNTCQDFWQMVWEQGVAIIAMVTAEEEGGREKSFRYWPRLGSRHNTVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSYLEEIQSVRRHTNSTSEPKSHNPPLLVHCSAGVGRTGVVILSEIMVACLEHNEVLDIPRVLDMLRQQRMMLVQTLGQYTFVYRVLIQFLKSSRLI
What is the function of this protein?
May be involved in the regulation of growth and differentiation of liver cells.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 21, Protein-tyrosine phosphatase PTP-RL10.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PCOD_ECOLX
Sequence: MNDLIMIVIRFLLYLDLMVIFGLPFFQIYGISGVRHETYNLTNFRSFITFAVVTGIILTGINMLLVSNAMSGVTDLRELSIHVIEMVIEETDVGISWIVRLCALFTTLGALFLYTNKRVLSCLLMTMSGGVALATLAWGGHAVMHDGLHYYLHLLSDLTHLGAAGAWTGALVAFAILLMRRNEHNAQSVIVISDSLAKFATAGTVIVVALILSALVNYLYIAEGNLTPLFNSSWGRILLAKTALFVLMLLLAAANRFHLGPRLEVMVREGNYDRSVALMRNSILTEFVVAIIILGAVAWLGMLAPSQVS
What is the function of this protein?
Required for the copper-inducible expression of copper resistance.
What are the official names of this protein?
Copper resistance protein D.
What is the protein family that this protein belongs to?
Belongs to the CopD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HACE1_RAT
Sequence: MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVAGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGQTCEVLIQYHPRLFQTIVQMTQNEDLRENMLRQVLQHLSQQSESQYLKILTGLAEVATTNGHKLLSLSSSYEAQMKSLLRIVRIFCHVFRIGPSSPSNGMDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKEDSADITSILLKQKGQDQEASCISAFEPPGPGSYERLSTGPGESKPDVLAGKQEASADCQDVISVTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVSENDILLVHRDSIFRSSCEIVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDMTQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
What is the function of this protein?
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases.  Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion.  Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division.  Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens.  May also act as a transcription regulator via its interaction with RARB.
What are the official names of this protein?
E3 ubiquitin-protein ligase HACE1, HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1, HECT-type E3 ubiquitin transferase HACE1.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane. Cytoplasm. Endoplasmic reticulum. Note=A significant portion localizes to the endoplasmic reticulum. Targeted to Golgi membrane via its interaction with Rab proteins.
Protein: DAZ1_CAEEL
Sequence: MMSPPLRYQKDQQNQQHQQNQSQQAAHQMVSFMPQTPTSLPSTPIQLYPTGAAALIPAPPTYELIPNRIFVGGFPTSTTETELREHFEKFFAVKDVKMVKSLDGQSKGYGFITFETEDQAEEIRKLTPKQLEFRSRKLNLGPAIRKINSNSFQPSYAIATPSQLVAASPGPFSYAIPASPSPYSGYSYPASPQMFVYPPLRSQDQSRQQSEQQTTPQNSPTNLQHQQSPQVFFGGDQDPIRSYASAVAGVEKSEVSPEKHESVSPQPLLPNQNVLNTQYSQGQQQWNSNVQQQQQQQMDSNNGGPYYNENYSQGYTRPHPYQQFAQSGVYMNSQGMYHSSYSYMTPPLAPGQYPQMMSAPYWQQQQQHHQSHAYAGYNPAYNNWVGPSGDMNQFKQNPSNYFYQNYPGNFSQQHTMGNNENTFSLPLQAPRQGKKSRKPSECQDKKTKSPIKGARTERPSSSASTPDAKYQKNHRYPVHLSPLSASLQSLAISSPTKNN
What is the function of this protein?
RNA-binding protein that plays a central role in oogenesis, but not for spermatogenesis.  Required for meiotic entry and germline differentiation, at the pachytene stage of meiosis I of female germline regardless of the sex of the soma.  May act by regulating translation of specific mRNAs, possibly by binding to their 3'-UTR.
What are the official names of this protein?
DAZ protein 1.
What is the protein family that this protein belongs to?
Belongs to the RRM DAZ family.
Protein: Y048_ALCBS
Sequence: MPSFDIVSEIDEVALRHAVENANRELSTRFDFRGVEASIAQNGLAVTLKTESDFQVRQLEELFTKACLKQNISAAGADKPEELEHSGKTFSLTLTFRQGIDQPVAKQIVKLIKESKIKVQASIQGDQVRVNGKKRDDLQAVMALLRESKIETPLQFNNFRD
What are the official names of this protein?
UPF0234 protein ABO_0048.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: CARS_TANPA
Sequence: MSAKEEKVIRPIVHFPPSVWADQFLIFDDEQAEQANVEQVVNELREDVRKDIVSSLDVQAEHTNLLKLIDAIQRLGIAYYFEGEIEQALQHIYDTYGDDWKGRSPSLWFRIFRQQGFYVSCDIFKNYKEEDGSFKESLTNDVEGLLELYEATYLGVQGEGILDDALVFTRTCLDKLAKDLVHSNPTLSTHIQEALQQPLHKRLTRLEALRYIPTYEQLSSHNESLLKLAKLGFNLLQSLHRKELSEVSRWWKGLDIPNNLPYARDRMVECYFWALGVYFEPKYSRARIFLAKVISLATVLDDTYDAYGIYEELKIFTEAIQRWSITCIDTLPEYMKLLYKGVLNIYKEMEEIMGKEGKAHHLSYAKESMKEFIRSYMMEAKWANEGYVPTAEEHMSVAFVSSGYSMLATTCFVGMGDIVTDEAFEWALTKPPIVKASCAIARLMDDIHSQKEEKERIHVASSVESYMKQYDVTEEHVHKVFHKKIEDAWKDITRESPVCKDIPMPLMTRVINLARVMDVLYKHKDGFTNVGQELKDHIKSLLVHPIPI
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of beta-caryophyllene, a sesquiterpene with anti-inflammatory and anti-carcinogenic activities.
What are the official names of this protein?
E-beta-caryophyllene synthase, TpCarS.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: TORD_PHOPR
Sequence: MQEFIAFNEQRAEIYWWMSSLLARELTNEDVTEYHGDEMFTFLSGLGMTPELKEPVEAFRNAINTLKTREDAQLELAADFCGLFLSTPKSGALPYASIYVGESGLLNDKPAQDMNVLMEEYGIAQRKEFNEPADHIAVELDFMGNLIIQANQELDEEKREALMQAQLAFVNDMLLNWIPAFAQSCKARDDFGFYTASVNLLVAFCQLDAAFLLGEE
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E4PD_ENT38
Sequence: MTVRVAINGFGRIGRNVIRALYESGRRAEITVVAINELADAVGMAHLLKYDTSHGRFAWDVRQEREQLFVGDDAIRVLHEQSIDALPWRELGVDVVLDCTGVYGNREHGEAHLAAGAKKVLFSHPGGHDLDATVVYGVNHHELQAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKASEVNLLLQKAAQGSFHGIVDYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAAQGFR
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYF1_CRYNB
Sequence: MASTSLVDSLTSHFPLTLPIPTPITHPHLIPSADLPVEEDLLHNPENLRSWLSYIHNVKEKIAADEPAKGGVLSPEEEILGPLASKNARDGLQRLVSIYERAIAVFPTSYKLWKAYYLTRQSYVLGELTNDAKEARSQQAKRGAAYKTNVRELLDGAEEAHEWTGGLDPVVGYAEWRSLVATGERMIMCLPNLPIPWLLHLGVLLHPKCPSVFKNGSYARRAFDRALRTLPPSLHGRVWGLYLRWAEIVGGDAGERVWRRYLKVDPSLTERHITYLLEAEEPRPLAAAKYLLSIARRAQQNLYSSLEGKSPYQLFVDFLELVEKYADQIGMDEEGTLELQRTKRAVEEKVDGEQPQVEGQEQQPQEEPASINGRLMRIAGPPVPLEQGKLFKPVNAASAQAPTQLTYDEDTDPSNPRLLDVEGIVERDGLQVYKDQAGRLWTGLATYWIKRGEFERATATFERGLAAVVTIRDFTQIFDAYAEFSETMISTLMDALADEDNLEDEDFDAEETEQELDERMKSFEELMDRRPFLVNDVLLRRNPNEVVEWEKRIALHGDDDAKVVEAYVKALDTINPRKATGPLYPLYVNFAKFYEEGGSKDDNGEPRNEPDLEQARKIFERATKVPFKAVDELAEVWCEWAEMELRNENYEEAIRLMQRATTVPKNTKINYYDDNIPPQSRLFKSLKLWSYYSDLEESIGTVESTKAVYDKIMELKIANAQVIVNYATFLEENKYFEESFKVYERGIELFHFPIAFEIWNIYLSKFVKRYGGKKLERARDLFEQALENCPEKFCKPLYLMYAKLEEEHGLAKRAMGIYDRAASTVQDSDKFEMYTIYIAKATANFGLPATRPIYERALESLPDKQTAEMCRRFARMERKLGEIDRARAIYAHASQFCDPRIEPEFWQEWNDFEIETGSEDTFREMLRIKRAVQASFNTETSFIAAQAAAASKGTEKPTDTSAQEAQDAADPMAAMERELSAAGADGARKGGAPAFVASTLNKTNANGIDEGGEETGEMANPDAIVMDEDEF
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle progression.
What are the official names of this protein?
Pre-mRNA-splicing factor SYF1.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ITB6_BOVIN
Sequence: MGIELLCLFFLCLGRNDHVQGGCAVGGAETCEDCLLIGPQCAWCSQENFTHLSGVGERCDTPANLLAKGCQLTFIENPVSQVEILTNKPLSIGRQKNSSDIVQISPQSLALKLRPGLEQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSLLSKEMSKLTSNFRLGFGSFVEKPISPFMKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDSKNEYSMSTILEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGVLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTAICNTGIPVPHQKKCSHMKVGDTASFNVTVSLPNCERRSRHIILKPVGLGDALEILVSPECSCDCQKEVEVNSSKCNNGNGSFQCGVCACHPGHMGHHCECGEDTLSTESCKEAPGRPSCSGRGDCYCGQCVCHLSPYGNIYGPYCQCDNFSCVRHKGLLCGDNGDCDCGECVCRSGWTGEYCNCTTSTDPCVSEDGILCSGRGDCVCGKCICTNPGASGPTCERCPTCGDPCNSKRSCIECYLSADGQAQEECVDKCKLAGATINEEEDFSKDSFVSCSLQGENECLITFLLTTDNEGKTVIHSINEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHKEKQKVDLSTDG
What is the function of this protein?
Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity).  It recognizes the sequence R-G-D in its ligands (By similarity).  ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity).  Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity).
What are the official names of this protein?
Integrin beta-6.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.
Protein: ATPD_BIFLS
Sequence: MRGEASRIADRESRDSLAPKLRDTREDAWRIGNELFTITKVLDDSIQLERALTDPSRPVADKVAVLTELLGDNVHPMTMEIMTDLVSRHWSRARDIANAVEDFGVDAMMYYADATGATLQVSVELSELHSALLNLPVVRAKLYDYQATSEARVKLFREVFSGKTLNKVTMRLAEHATCNLRRRRYLETIQWMINKFSRHMGESMVTVTTATPLKKEQIKRLVEVYSAKVGRQVHINSVVDPTVLGGMRIQVGDEVTDNTVVAQLQNLHRKVQTEATPA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HIS4_CAMC5
Sequence: MEIFPAIDLKEGKAVRLSKGDMRSAKIYSHAPQELAKIFEGYGARWLHVVDLDGAFAGETVNFDAVEKIIKSTNLKVQIGGGIRDEARIKRYLDIGASRVILGSVALNEPNFVREMAKIYPVVVGIDAKEGFVATQGWAEVSQMRASELAAKFATAGVKAIICTDIAKDGMLGGVNLDFTLEIARASGVDTIASGGVKDMSDIMRLKDSGEVAGVIVGKAYYEGKIDLKEAFRKVL
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDIN1_MOUSE
Sequence: MILTKAQYEEIAQCLVSVPPTRQSLRKLKQRFPSQSQATLLSIFSQEYQKHIKRTHAKHHTPEAIESYYQRYLNGVGKNGAAPVLLELANEVDYAPSLMARIILERFLQGHEQTPPSKSVINSMLRDPSQIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGYEHEVLLRDLLLKKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIHWIESKASFGDECSHHAYLHGQFWSYWNRFGPGLVIYWYGFIQELDCNRERGILLKASFPTDIVTLCHSTA
What is the function of this protein?
Plays a role in erythroid cell differentiation.
What are the official names of this protein?
CDAN1-interacting nuclease 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear.
Protein: PAND_SALDC
Sequence: MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLDASGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCAEVGDIVIIASFVTMSDEEARTWSPKVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHL_BACSU
Sequence: MMDVKSISVRVDGTEIQARAGATILDILNENGIEYPQICHVPEVDPIQTCDTCIVEANGKLVRSCATVAENGMSIDLSGNRVKEAQTEAMDRLLENHLLYCTVCDNNNGNCTLHNTAEMMGIEHQKYPYTPKEDPSCAVDMSHPFYRYDPNQCIACGQCVEVCQNLQVNETLSIDWERERPRVIWDEGVPINESSCVSCGQCVTVCPCNALMEKSMLGQAGFMTGIKEDVMEPMIDLVKNVEPGYGSIFAISEVEAAMRETRTKKTKTVCTFCGVGCSFEVWTKGRDILKIQPVSDAPVNAISTCVKGKFGWDFVNSKERITKPLIRKNGAFVESSWEEALDLVASRLGSIKEQYGKGSVGFISSSKITNEENYVIQKLARQVFETNNVDNCSRYCQSPATDGLFRTVGMGGDAGTIKDIAKAGLVIIVGANPAEGHPVLATRVKRAHKLHGQKLIVADLRKNEMAERSDLFISPKQGTDQVWLMAVTKYMIDQGWHDQAFIDENVNYFEDYKETLKTYTLDYAERITGLSKENIIQIAEMIRDADGTCVLWGMGVTQNTGGSDTSAAISNLLLATGNYRRPGAGAYPLRGHNNVQGACDMGTLPGWLPGYQHITDDKARAKFEEAYGVEIDGKPGLDNIQMLHAIEEGKMKAMYLVGEDMALVDSNANHVHDILSSLDFFVVQDIFLSRTAQYADVVLPATPSLEKDGTFTNTERRVQRLYQALPTLGDAKPDWWIIQEVANRLGANWNYSHPSDIFSEMASLSPLFAKASYEVLEGWNSFLWGSFTGESTPLLYEDGFNFPDKKARFALSDWTEPAAFPEEYDLHINNGRMLEHFHEGNMTNKSKGIQAKVPNVFVEISPELAQERGVCDGSLVRLVSPFGAVKLNALITDRVRKNELYLPMNSTDKESAINFLTGPAADKRTNTPAYKQTKVRMEVLGGCETAPLPKTNPRNKKRHPQNGVEAERKWNRPGYVHLTD
What are the official names of this protein?
Putative formate dehydrogenase YrhE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
Protein: DCYD_SHISS
Sequence: MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTPMAMGGNKLRKLEFLAADALREGADTLITAGVIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCEALTDPNAQLEELATRVEAQGFRPYVIPVGGSNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGVTVSRSVADQLPKVVNLQQAIAKELELTASAEIILWDDYFAPGYGVPNDEGMEAVKLLARLEGILLDPVYTGKAMAGLIGCISQKRFKDEGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: PSN2_MOUSE
Sequence: MLAFMASDSEEEVCDERTSLMSAESPTSRSCQEGRPGPEDGESTAQWRTQESEEDCEEDPDRYACSGAPGRPSGLEEELTLKYGAKRVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPLPGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWNTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI
What is the function of this protein?
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein).  Requires the other members of the gamma-secretase complex to have a protease activity.  May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane.  May function in the cytoplasmic partitioning of proteins (By similarity).  The holoprotein functions as a calcium-leak channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is involved in calcium homeostasis (PubMed:16959576).  Is a regulator of mitochondrion-endoplasmic reticulum membrane tethering and modulates calcium ions shuttling between ER and mitochondria (By similarity).
What are the official names of this protein?
Presenilin-2, PS-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: Y3208_YERPS
Sequence: MNLQHHFLIAMPSLQDPQFKRSVIYICEHDEKGAMGLVINKPLEQLTVETILEKLKIKSPSRDPAIRLDNVVLAGGPLAEDRGFILHSPQEGFASSIHISPETMITTSKDVLETLGTSGQPKNLLVALGYASWRQGQLEQELLDNVWLTTEADTHILFNTPIAERWQAAANKLGINIFNIAPQAGHA
What are the official names of this protein?
UPF0301 protein YPTB3208.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: LPXB_PSEF5
Sequence: MSTLRIALVAGEASGDILGAGLMRALKVQHPAVEFIGVGGPLMEAEGLVSYFPMERLAVMGLVEVLGRLRELLARRKKLIQTLIAEKPDVFIGIDAPDFTLNIELKLRQARIKTVHYVSPSVWAWRQKRVLKIREGCDLMLTLFPFEARFYEEKGVPVKFVGHSLADAIPLEADRAAARAELGLPEGPLVALMPGSRGGEVGRLGALFLDAAQRLRAMRPGVRFIMPCASPERRVQLEQLLANRDLPLTLLDGQSHKALAACDAVLIASGTATLEALLYKRPMVVAYRLAPLTFWILKRMVKSPYISLPNLLAQRLLVPELLQDDATADALAQTLSPLIEGGEEQTRGFDEIHRTLRRDASNQAAQAVLGLIGK
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: PAI2_HUMAN
Sequence: MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP
What is the function of this protein?
Inhibits urokinase-type plasminogen activator.  The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
What are the official names of this protein?
Plasminogen activator inhibitor 2, PAI-2, Monocyte Arg-serpin, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted, extracellular space.
Protein: RK36_NICSY
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MEGF6_RAT
Sequence: MPVRAEARAAWRVVALALLLLPAMPAASPPLTPRPLQPSMPHVCAEQKLTLVGHRQPCVQAFSRIVPVWRRTGCAQQAWCIGQERRTVYYMSYRQVYATEARTVFRCCPGWSQKPGQEGCLSDVDECASANGGCEGPCCNTVGGFYCRCPPGYQLQGDGKTCQDVDECRAHNGGCQHRCVNTPGSYLCECKPGFRLHTDGRTCLAISSCTLGNGGCQHQCVQLTVTQHRCQCRPQYQLQEDGRRCVRRSPCAEGNGGCMHICQELRGLAHCGCHPGYQLAADRKTCEDVDECALGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAGNGGCSHGCSHTSTGPLCTCPRGYELDEDQKTCIDIDDCANSPCCQQACANTPGGYECSCFAGYRLNTDGCGCEDVDECASGHGGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCTSLEESVVDLDGRLPFVRPLPHIAVLRDELPRLFQDDYGAEEEAAAAELRGEHTLTEKFVCLDHSFGHDCSLTCDDCRNGGTCFPGQDGCDCPEGWTGIICNETCPPDTFGKNCSSPCTCQNGGTCDPVLGACRCPPGVSGAHCEDGCPKGFYGKHCRKKCHCANRGRCHRLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNPKDGSCSCKAGFQGERCQAECESGFFGPGCRHRCTCQPGVACDPVSGECRTQCPPGYQGEDCGQECPVGTFGVNCSGSCSCVGAPCHRVTGECLCPPGKTGEDCGADCPEGRWGLGCQEICPACEHGASCNPETGTCLCLPGFVGSRCQDTCSAGWYGTGCQIRCACANDGHCDPTTGRCSCAPGWTGLSCQRACDSGHWGPDCIHPCNCSAGHGNCDAVSGLCLCEAGYEGPRCEQSCRQGYYGPSCEQKCRCEHGAACDHVSGACTCPAGWRGSFCEHACPAGFFGLDCDSACNCSAGAPCDAVTGSCICPAGRWGPRCAQSCPPLTFGLNCSQICTCFNGASCDSVTGQCHCAPGWMGPTCLQACPPGLYGKNCQHSCLCRNGGRCDPILGQCTCPEGWTGLACENECLPGHYAAGCQLNCSCLHGGICDRLTGHCLCPAGWTGDKCQSSCVSGTFGVHCEEHCACRKGASCHHVTGACFCPPGWRGPHCEQACPRGWFGEACAQRCLCPTNASCHHVTGECRCPPGFTGLSCEQACQPGTFGKDCEHLCQCPGETWACDPASGVCTCAAGYHGTGCLQRCPSGRYGPGCEHICKCLNGGTCDPATGACYCPAGFLGADCSLACPQGRFGPSCAHVCACRQGAACDPVSGACICSPGKTGVRCEHGCPQDRFGKGCELKCACRNGGLCHATNGSCSCPLGWMGPHCEHACPAGRYGAACLLECFCQNNGSCEPTTGACLCGPGFYGQACEHSCPSGFHGPGCQRVCECQQGAPCDPVSGQCLCPAGFHGQFCEKGCESGSFGDGCLQQCNCHTGVPCDPISGLCLCPPGRTGAACDLDCRRGRFGPGCALRCDCGGGADCDPISGQCHCVDSYMGPTCREVPTQISSSRPAPQHPSSRAMKH
What are the official names of this protein?
Multiple epidermal growth factor-like domains protein 6, Multiple EGF-like domains protein 6, Epidermal growth factor-like protein 3, EGF-like protein 3.
What are the subcellular locations of this protein?
Secreted.
Protein: VE5_HPV33
Sequence: MIFVFVLCFILFLCLSLLLRPLILSISTYAWLLVLVLLLWVFVGSPLKIFFCYLLFLYLPMMCINFHAQHMTQQE
What are the official names of this protein?
Probable protein E5.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E5 protein family.
Protein: BI2L2_HUMAN
Sequence: MAPEMDQFYRSTMAIYKSIMEQFNPALENLVYLGNNYLRAFHALSEAAEVYFSAIQKIGERALQSPTSQILGEILVQMSDTQRHLNSDLEVVVQTFHGGLLQHMEKNTKLDMQFIKDSRQHYELEYRHRAANLEKCMSELWRMERKRDKNVREMKESVNRLHAQMQAFVSESQRAAELEEKRRYRFLAEKHLLLSNTFLQFFGRARGMLQNRVLLWKEQSEASRSPSRAHSPGLLGPALGPPYPSGRLTPTCLDMPPRPLGEFSSPRSRHGSGSYGTEPDARPASQLEPDRRSLPRTPSASSLYSGSAQSSRSNSFGERPGGGGGARRVRALVSHSEGANHTLLRFSAGDVVEVLVPEAQNGWLYGKLEGSSASGWFPEAYVKALEEGPVNPMTPVTPMTSMTSMSPMTPMNPGNELPSRSYPLRGSHSLDDLLDRPGNSIAPSEYWDGQSRSRTPSRVPSRAPSPAPPPLPSSRRSSMGSTAVATDVKKLMSSEQYPPQELFPRGTNPFATVKLRPTITNDRSAPLIR
What is the function of this protein?
Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures.  Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups.  There seems to be no clear preference for a specific phosphoinositide (By similarity).
What are the official names of this protein?
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2, BAI1-associated protein 2-like protein 2, Planar intestinal- and kidney-specific BAR domain protein, Pinkbar.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane. Note=Localizes to RAB13-positive vesicles and to the plasma membrane at intercellular contacts.