PharMolix/UniProtQA huggingface dataset:
Protein: DPO3A_RICPR
Sequence: MQPEFIHLRTQSSYSFLESALTIEKVVELALLHKMPALCLSDRGNLFGSLEFSLYAVKKKLQPIHGVILNIQYDINAFAQILLIAKDETGYKNLLKLSSLTFTKNDRKICEHIGFEDLIKYQEGVIALCCYTDGIVGKCLLARKQEQAILFARRLQAILGDRFYFEIMRHDLPEEQFIENSYIQIASELSIPIVATNKVLFSEKSMHYAHDVLLCISEGVTKEYPDRKTVSENCYFKSPAEMRKLFSDLPNAIQNTINLRERCYFAAHPNPPMLPNFSTQDISETYLIRKYATEGLLARLVTKFKAENISLEHQEKLKTEYFTRLNYELDIICNMNFAGYFLIVSDFIKWSKKQGILVGPGRGSGAGSVVAWSLLITDLDPIKFGLLFERFLNPERISMPDFDIDFCQERREEVINYVRSKYGPNRVGQIITFGKMQAKAVIKDVARVLSLPYKLADYLTELVPFSAINPVSLEQAIREVPELANAAKGNGLYNLEGDAELIKLVLDTSLILEGLHRHSSTHAAGIVIAGTDLVDIVPVYKDANADMLIVGYSMKYSEIAGLIKFDFLGLQTLTVITNCKKLLKEQGIKIDFDDMTFDDKKTYQMLCKGKGVGVFQFESIGMKDALRRLKPDSIHDLIALGALYRPGPMENIPTYIACKHKLQQPDYLHKLLEPILEETYGVVIYQEQVQRIAQVLAGYTLGAADLLRRAMGKKIKKEMEEQEEIFVKGAIANNISPSQAKSIFSTVAKFAGYGFNKAHAAAYGVISYQTAYLKANYPAEFLVACLNLELNNHDKINLFLQEAKDNGIKIIAPNINISEGYFSVKSSNTVITHSTKSVISRLNCDIKKIAKDTAVKPLYCKDESTIIFALGAIKGVTANFGKLVTDERKARGAFKSITDFIERLPPKSINSKLLENLIKAGCFDELHDNRLQLFLSIPKLIAYSTSYHQEQESNQFSLIKVSSLSPTILVSSDYADKNTLAFYEFEAMGLFLSNHPLTEYQGIFSRLNILNTRDLYNKLPNGTNRVTLAGVIQKKDSRMSARGRFVTLVLSDPENIFELTIFSEEVLKDYVHLLDVKSLVVVNCDVVKDEGGIKLTAKSFLSIEDVMNNRQFELQLYPQNYAELEQIITLLASRTSNGYQSNAKATIYLQSKDVKHFIAKITLSETFFLQVQDFEVLNQYIR
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATA2_HORVU
Sequence: MDPCKFRPSSSFDTKTTTTNAGQPVWNDNEALTVGPRGPILLEDYHLLEKIAHFARERIPERVVHARGASAKGFFECTHDVTGLTCADFLRAPGARTPVIVRFSTVIHERGSPETIRDPRGFAVKFYTREGNWDLLGNNFPVFFIRDGIKFPDVIHAFKPNPKSHVQEYWRVFDFLSHHPESLHTFFFLFDDVGIPTDYRHMDGFGVNTYTFVSRAGKSHYVKFHWRPTCGVSCLMDDEATLVGGKNHSHATQDLYDSIDAGNFPEWKLFVQVIDPDEEDRFDFDPLDDTKTWPEDLVPLQPVGRLVLDRNVDNFFNENEQLAFGPGLVVPGIYYSDDKMLQCRVFAYADTQRYRLGPNYLMLPVNAPKCGFKNNHYDGAMNFMHRDEEVDYYPSRHAPLRHAEPASFPVPTRPVVGKREKTRIKKENDFVQPGERYRSWAPDRQDRFVRRFSDALAHPKVSHELRVIWIDFLSKCDKSCGMKVANRLNVKPSM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 2.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: TRHO_BUCBP
Sequence: MLYLYNKHPRIKLRNAAIFDNINRVTVSFYKYIFIHEPIKFRNSLYRMFFKFNIFGRVYIANEGINAQISIPKKIYHKAINIITTSFAVLKDINVNLALDNRESFWVLRMKVRKKILFDNLPIDFFDPNNVGTYLSAKDVNNMLENKNSVLVDMRNHYEYKIGHFDSAINVPVNTFREQLFHIVDFLKHYKNRDIIMYCTGGIRCEKATAWIKYNGFKNVYQIKGGIIKYVRDARIENLLVKFRGKNFVFDERMSEVVSKDVLSKCDQCENLCDTYVNCFNSRCHNLFIQCNFCRKKFHNCCSEHCFKTLLK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: FBK68_ARATH
Sequence: MSNEAPEVEPHSKRRKKEASPSSSSGFLQSLPEAVAMICLARVSRLDHAALSLVSKSCRSMVLSPELYQTRSLIGYAEKFLYVCFCMPTDETLCCHEKINGNRSLNVLFLDCRSHKWHHVTSMRVARVSPEVSVVDGKINVWGGCKYKHYYDWGEVFDPKTQTWADMSIPKPVREEKIYVVDSWDVGSYYYLPSKSIWEKGNQDSKRSKDWCLIDKLIYSCGNDGGIYWCEAGELDWCDAVGIDWREVFGLEFLSKELRESRVVYFGGKMVKVWESYKIMYNISLNLEELLPETQLTNLTELGHNVLVFWEKLECCCDGFKILEIWCAEISLERWEGGEILGRCDWCHPILAINLLTVDPLFYHSMVLYSIPVDV
What are the official names of this protein?
Putative F-box/kelch-repeat protein At3g24610.
Protein: INSM1_BOVIN
Sequence: MPRGFLVKRSKKSTPVSYRIRGGEDGDRALLLLPGCGGARASPPAPGPGPVPGPLQPPPPTERAHAALAAALACAPGPPPPPPGLRAAHFGNPEAAHPAPLYSPTRPVSREHEKHKYFERSFNLGSPVSAESFPTPAALLVGGGGGGGGGGANGAGGGGTCSGDPLLFAPAELKMGTAFSAAAEAARGPGPGPPLPPAAALRPPGKRPSPPASAAAAAEPPAKVAKAPGSKKPKAIRKLHFEDEVTTSPVLGLKIKEGPVEAPRGRAGGAARPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPAPAAARACEPETPARAEAREATGGGGSDRDTPSPGGVSESGSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQAKGAPPPAPPAEDLLALYPGPDEKVPQEAAGDGEAAGVLGLSASAECHLCPVCGETFPSKGAQERHLRLLHAAQVFPCKYCPATFYSSPGLTRHINKCHPSENRQVILLQVPVRPAC
What is the function of this protein?
Sequence-specific DNA-binding transcriptional regulator that plays a key role in neurogenesis and neuroendocrine cell differentiation during embryonic and/or fetal development.  Binds to the consensus sequence 5'-[TG][TC][TC][TT][GA]GGG[CG]A-3' in target promoters.  Acts as a transcriptional repressor of NEUROD1 and INS expression via its interaction with cyclin CCND1 in a cell cycle-independent manner.  Negatively regulates skeletal muscle-specific gene expression in endocrine cells of the pituitary by inhibiting the Notch signaling pathway.  Represses target gene transcription by recruiting chromatin-modifying factors, such as HDAC1, HDAC2, HDAC3, KDM1A and RCOR1 histone deacetylases.  Binds to its own promoter, suggesting autoregulation as a self-control feedback mechanism.  Competes with histone H3 for the same binding site on the histone demethylase complex formed by KDM1A and RCOR1, and thereby inhibits demethylation of histone H3 at 'Lys-4'.  Promotes the generation and expansion of neuronal basal progenitor cells in the developing neocortex.  Involved in the differentiation of endocrine cells of the developing anterior pituitary gland, of the pancreas and intestine, and of sympatho-adrenal cells in the peripheral nervous system.  Promotes cell cycle signaling arrest and inhibition of cellular proliferation.
What are the official names of this protein?
Insulinoma-associated protein 1, Zinc finger protein IA-1.
What is the protein family that this protein belongs to?
Belongs to the INSM1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y181_AFV2P
Sequence: MTILNYNTIGIKGKTAEEFLYRYITGERKFAVIRSVNDNKLDVMKLKVMTIYEKVIASGDAKIRTIIPVVDDSGYVDNYKLMKYKNLILRYDNLPAHAIAKTVYINAIKMGYTYNYKKRVVSLLIFTIDKLSLTLNCDTRNVVVNVVRKICNDKGFENCNDIDKSNVASKVKTYISAFAKK
What are the official names of this protein?
Uncharacterized protein ORF181.
Protein: TRI25_MOUSE
Sequence: MAELNPLAEELSCSVCLELFKEPVTTPCGHNFCMSCLDETWVVQGPPYRCPQCRKVYQVRPQLQKNTVMCAVVEQFLQAEQARTPVDDWTPPARFSASSAATQVACDHCLTEIAVKTCLVCMASFCQEHLRPHFDSPAFQDHPLQSPIRDLLRRKCTQHNRLRELFCPEHGECICHICLVEHKTCSPTTLSQASADLEYKLRNKLTIMHSHINGATKALEDVRSKQQCVQDSMKRKMEQLRQEYMEMKAVIDAAETSSLRKLKEEEKRVYGKFDTIYQVLVKKKSEMQKLKAEVELIMDKGDEFEFLEKAAKLQGESTKPVYIPKIDLDHDLIMGIYQGAADLKSELKHSIKKLQKKSEEHNGSGNKGDQTQSTFKPVQPSKKTIQEKKTKKTPVAPGPPSHFSPNKLPTFGAPGQSLDSKATSPDAAPKASAAQPDSVGVKAKVLENFLTKSRTELLEYFVKVIFDYNTAHNKVSLSNKYTTASVSDGLQHYRSHPQRFTYCSQVLGLHCYKNGIHYWEVELQKNNFCGVGICYGSMERQGPESRLGRNPNSWCVEWFNNKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVTEKVHLMYKFKVDFTEALYPAFWVFSAGTTLSICSK
What is the function of this protein?
Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase.  Involved in innate immune defense against viruses by mediating ubiquitination of RIGI and IFIH1.  Mediates 'Lys-63'-linked polyubiquitination of the RIGI N-terminal CARD-like region and may play a role in signal transduction that leads to the production of interferons in response to viral infection.  Mediates 'Lys-63'-linked polyubiquitination of IFIH1.  Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway.  Mediates estrogen action in various target organs.  Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (By similarity).  Plays a role in promoting the restart of stalled replication forks via interaction with the KHDC3L-OOEP scaffold and subsequent ubiquitination of BLM, resulting in the recruitment and retainment of BLM at DNA replication forks (PubMed:29125140).  Plays an essential role in the antiviral activity of ZAP/ZC3HAV1; an antiviral protein which inhibits the replication of certain viruses.  Mechanistically, mediates 'Lys-63'-linked polyubiquitination of ZAP/ZC3HAV1 that is required for its optimal binding to target mRNA.  Mediates also the ubiquitination of various substrates implicated in stress granule formation, nonsense-mediated mRNA decay, nucleoside synthesis and mRNA translation and stability (By similarity).
What are the official names of this protein?
E3 ubiquitin/ISG15 ligase TRIM25, Estrogen-responsive finger protein, RING-type E3 ubiquitin transferase, RING-type E3 ubiquitin transferase TRIM25, Tripartite motif-containing protein 25, Ubiquitin/ISG15-conjugating enzyme TRIM25, Zinc finger protein 147.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, Stress granule. Nucleus. Note=Localized to DNA replication forks.
Protein: CYB6_PINKO
Sequence: MGKVYDRFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYLMTEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVILAVLTVSFGVTGYSLPWDQIGYWAVKIVTGVPEAIPVIGSPLVELLRGSVSVGQSTLTRFYSLHTFILPLLTAVFMPMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PSD10_HUMAN
Sequence: MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG
What is the function of this protein?
Acts as an proto-oncoprotein by being involved in negative regulation of tumor suppressors RB1 and p53/TP53.  Overexpression is leading to phosphorylation of RB1 and proteasomal degradation of RB1.  Regulates CDK4-mediated phosphorylation of RB1 by competing with CDKN2A for binding with CDK4.  Facilitates binding of MDM2 to p53/TP53 and the mono- and polyubiquitination of p53/TP53 by MDM2 suggesting a function in targeting the TP53:MDM2 complex to the 26S proteasome.  Involved in p53-independent apoptosis.  Involved in regulation of NF-kappa-B by retaining it in the cytoplasm.  Binds to the NF-kappa-B component RELA and accelerates its XPO1/CRM1-mediated nuclear export.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit p28, Gankyrin, p28(GANK).
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IHFA_ACIBT
Sequence: MTALTKADMADHLSELTSLNRREAKQMVELFFDEISQALIAGEQVKLSGFGNFELRDKRERPGRNPKTGEEIPISARRVVTFRAGQKFRQRVGNEQID
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: SCX1_CENEX
Sequence: MNSLLMITTCLVLFGTVWAKEGYLVSKSTGCKYECFWLGKNEGCDKECKAPNQGGGYGYCHAFACWCENLPESTPTYPIPGKSCGKK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Neurotoxin Cex1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GATA_CAMJD
Sequence: MITLKEALKYSKEELENLKKELNEKAKKEKKLGAYIEQFLDKDLSVSGEGVPVAIKDNISVKGWELTSASKILQGYIAPYDASAIVNLKANGFAPFGRCNMDEFAMGSSTASSCYGKTLNPLNFERVPGGSSGGSAAAVAGGLALASLGSDTGGSVRQPAAFCGCVGFKPSYGRVSRYGLASYSSSLDQIGVLTQNVEDAAILYDAIAGYDKMDSTSANIEFIKTAPNLNANEKLKIAVIENYVNDADTEVKNALLKTIDMLKANGHEIVYKNLLDSKFDIAAYYIIATAEASANLSRYDGVRYGKRSENIQNLKEMYVNTRSEGFGEEVKRRILLGTFVLSSGYYDAYYIKAQKARAFIKAKYEEILQDCDLIFMPVTPTMAFKFDTQKSPMQTYLEDVYTISVNLAGLGGISVPVAKDKEGLNISAQLICKAYDEQTLLDGALSLEQMIKN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RL20_DEHMC
Sequence: MARIKGGLATHKRHKKVLALTKGHASTRHSLFKRAHESMVHAMSYAFAHRRARKGDMRRLWITRINAAARAEGLTYGELISGLKVAGIDINRKVLADMAISDTVAFAAVAAKAAAAKAN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RK35_SPIOL
Sequence: MAMASATATLSFKTPSLSLSPPSTRCSAAQGISLTHFNKQLKSTLNLSSSSSISSSKVQPIVLKNKRISTVDSSVSTSSPSFTVFAAKGYKMKTHKASAKRFRVTGKGKIVRRRAGKQHLLAKKNTKRKNRLSKLIQVDRSDYDNVIGALPYLKVNRKV
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
50S ribosomal protein L35, chloroplastic, CL35, Chloroplastic large ribosomal subunit protein bL35c.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL22_TRIGR
Sequence: MPGKTAQKGGRPSGKGKKKKQTLKFTIDCTLPVEDGIMDASNFEQFLQERIKVNGKTKNLTTNIVIERKKSKVTVTSEIAFSKRYLKYLTKKYLKKNNLRDWLRVVAANKESYELRYFQINQDDEEEEDD
What are the official names of this protein?
60S ribosomal protein L22, Development-specific protein 217.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL22 family.
Protein: THIOG_TRIV2
Sequence: MTRDIVIIGGGVIGLAIAVELKLRGTKVTVLCRDFPAAAAHAAAGMLAPDAEEITDEAMKSLCWRSRSLYPEWTSKLEDLTGLNTGYWPCGILAPVYEGQESKGVRIQENKGESPAYWLEKAVIHQYQPGLGEDVVGGWWYPEDAQVNNQALARVLWAAAESLGVELNDGITVEGLLQQQGQVVGVQTNTGIIQAEHYVLATGAWANELLPLPVTPRKGQMLRVRVPESVPELPLKRVLFGENIYIVPRRDRSIIIGATSEDVGFTPHNTPAGIQTLLQGAIRLYPQLQDYPIQEFWWGFRPATPDELPILGTSHCANLTLATGHYRNGILLAPITAALIADFIVEQKSDPLLSHFHYSRFQKQASTTPMFTHSANFSNGHAKNPPLPTLDSSLIIAGKSFHSRLMTGTGKYRSIEEMQQSVVASGCEIVTVAVRRVQTKAPGHEGLAEALDWSRIWMLPNTAGCQTAEEAIRVARLGREMAKLLGQEDNNFVKLEVIPDPKYLLPDPIGTLQAAEQLVKEGFAVLPYINADPMLAKRLEDVGCATVMPLASPIGSGQGLKTTANIQIIIENAKIPVVVDAGIGAPSEASQAMELGADALLINSAIALAQNPAAMAQAMNLATVAGRLAYLAGRMPIKTYASASSPVTGTIS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Bifunctional protein ThiO/ThiG.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y256_MYCPA
Sequence: MPRTDNDSWDITQSVGATALGVAAARAAETESENPLISDPFARIFVEAAGKGMWSIYADPALLTKADDLEPDLRGRLQLMIDFMATRTAFFDEFFLAAADAGVRQVVILAAGLDARSWRLPWPDGTVVYELDQPKVLDFKSTTLREHGAQPKAELVNVPIDLRQDWPKALQEAGFDASRPAVWSAEGLVRYLPAQAQDLLFERIDALSAPGSRLASNVPDSGFTDPDRLARQREDMRRMRAAAAKLVDAEITDFDDLWYPEERTPVDSWLRERGWDVSTATFAELMARYGRSIPQGAQDSMPPTLYVSARRRAG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_0256.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: TOR_ARATH
Sequence: MSTSSQSFVAGRPASMASPSQSHRFCGPSATASGGGSFDTLNRVIADLCSRGNPKEGAPLAFRKHVEEAVRDLSGEASSRFMEQLYDRIANLIESTDVAENMGALRAIDELTEIGFGENATKVSRFAGYMRTVFELKRDPEILVLASRVLGHLARAGGAMTSDEVEFQMKTAFDWLRVDRVEYRRFAAVLILKEMAENASTVFNVHVPEFVDAIWVALRDPQLQVRERAVEALRACLRVIEKRETRWRVQWYYRMFEATQDGLGRNAPVHSIHGSLLAVGELLRNTGEFMMSRYREVAEIVLRYLEHRDRLVRLSITSLLPRIAHFLRDRFVTNYLTICMNHILTVLRIPAERASGFIALGEMAGALDGELIHYLPTIMSHLRDAIAPRKGRPLLEAVACVGNIAKAMGSTVETHVRDLLDVMFSSSLSSTLVDALDQITISIPSLLPTVQDRLLDCISLVLSKSHYSQAKPPVTIVRGSTVGMAPQSSDPSCSAQVQLALQTLARFNFKGHDLLEFARESVVVYLDDEDAATRKDAALCCCRLIANSLSGITQFGSSRSTRAGGRRRRLVEEIVEKLLRTAVADADVTVRKSIFVALFGNQCFDDYLAQADSLTAIFASLNDEDLDVREYAISVAGRLSEKNPAYVLPALRRHLIQLLTYLELSADNKCREESAKLLGCLVRNCERLILPYVAPVQKALVARLSEGTGVNANNNIVTGVLVTVGDLARVGGLAMRQYIPELMPLIVEALMDGAAVAKREVAVSTLGQVVQSTGYVVTPYKEYPLLLGLLLKLLKGDLVWSTRREVLKVLGIMGALDPHVHKRNQQSLSGSHGEVPRGTGDSGQPIPSIDELPVELRPSFATSEDYYSTVAINSLMRILRDASLLSYHKRVVRSLMIIFKSMGLGCVPYLPKVLPELFHTVRTSDENLKDFITWGLGTLVSIVRQHIRKYLPELLSLVSELWSSFTLPGPIRPSRGLPVLHLLEHLCLALNDEFRTYLPVILPCFIQVLGDAERFNDYTYVPDILHTLEVFGGTLDEHMHLLLPALIRLFKVDAPVAIRRDAIKTLTRVIPCVQVTGHISALVHHLKLVLDGKNDELRKDAVDALCCLAHALGEDFTIFIESIHKLLLKHRLRHKEFEEIHARWRRREPLIVATTATQQLSRRLPVEVIRDPVIENEIDPFEEGTDRNHQVNDGRLRTAGEASQRSTKEDWEEWMRHFSIELLKESPSPALRTCAKLAQLQPFVGRELFAAGFVSCWAQLNESSQKQLVRSLEMAFSSPNIPPEILATLLNLAEFMEHDEKPLPIDIRLLGALAEKCRVFAKALHYKEMEFEGPRSKRMDANPVAVVEALIHINNQLHQHEAAVGILTYAQQHLDVQLKESWYEKLQRWDDALKAYTLKASQTTNPHLVLEATLGQMRCLAALARWEELNNLCKEYWSPAEPSARLEMAPMAAQAAWNMGEWDQMAEYVSRLDDGDETKLRGLASPVSSGDGSSNGTFFRAVLLVRRAKYDEAREYVERARKCLATELAALVLESYERAYSNMVRVQQLSELEEVIEYYTLPVGNTIAEERRALIRNMWTQRIQGSKRNVEVWQALLAVRALVLPPTEDVETWLKFASLCRKSGRISQAKSTLLKLLPFDPEVSPENMQYHGPPQVMLGYLKYQWSLGEERKRKEAFTKLQILTRELSSVPHSQSDILASMVSSKGANVPLLARVNLKLGTWQWALSSGLNDGSIQEIRDAFDKSTCYAPKWAKAWHTWALFNTAVMSHYISRGQIASQYVVSAVTGYFYSIACAANAKGVDDSLQDILRLLTLWFNHGATADVQTALKTGFSHVNINTWLVVLPQIIARIHSNNRAVRELIQSLLIRIGENHPQALMYPLLVACKSISNLRRAAAQEVVDKVRQHSGALVDQAQLVSHELIRVAILWHEMWHEALEEASRLYFGEHNIEGMLKVLEPLHDMLDEGVKKDSTTIQERAFIEAYRHELKEAHECCCNYKITGKDAELTQAWDLYYHVFKRIDKQLASLTTLDLESVSPELLLCRDLELAVPGTYRADAPVVTISSFSRQLVVITSKQRPRKLTIHGNDGEDYAFLLKGHEDLRQDERVMQLFGLVNTLLENSRKTAEKDLSIQRYSVIPLSPNSGLIGWVPNCDTLHHLIREHRDARKIILNQENKHMLSFAPDYDNLPLIAKVEVFEYALENTEGNDLSRVLWLKSRSSEVWLERRTNYTRSLAVMSMVGYILGLGDRHPSNLMLHRYSGKILHIDFGDCFEASMNREKFPEKVPFRLTRMLVKAMEVSGIEGNFRSTCENVMQVLRTNKDSVMAMMEAFVHDPLINWRLFNFNEVPQLALLGNNNPNAPADVEPDEEDEDPADIDLPQPQRSTREKEILQAVNMLGDANEVLNERAVVVMARMSHKLTGRDFSSSAIPSNPIADHNNLLGGDSHEVEHGLSVKVQVQKLINQATSHENLCQNYVGWCPFW
What is the function of this protein?
(Microbial infection) Required during infection by some potyvirus such as Watermelon mosaic virus (WMV) but not for turnip mosaic virus (TuMV).
What are the official names of this protein?
Serine/threonine-protein kinase TOR, Protein TARGET OF RAPAMYCIN, AtTOR.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Associates to polysomes when activated by auxin or cauliflower mosaic virus (CaMV) Tav protein.
Protein: THIM_BIFLO
Sequence: MSNSASSFTGVSSGYTAGTPVPADSPIRDNIADAVRRVRETTPLAQSFTNFVTINLVANAQLAAGGTAAMSFLPDDVIETAKIAGANYINVGTLLPFYKDALPEIAQRLNYLDKPWVLDPVAAGIGRTRTAILQAFKAAPPTMIRANASEVIALANMWGLNTETVGDASEHRPAGVESVDDVESATGAAVALAQYLTEQHAKHSSHDASTRCAVAVSGIADLVTDGETVYRLPGGSAMMTKIIGAGCSLGGVAATYLAVSDPLTAALSASLLYNRAGEVADTTSHGPGSFQVAFLDALWNVTAEQVAESEILVQ
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: SKIT6_MOUSE
Sequence: MGTIGVPLTAHCVVLFLLQMVALSTEQFTVNGLESPVLVPLGGNLELSCQLSPPQQAKHMEIRWFKNRYSEPVYLYRNGKDLNEAIVYKYVERTELLKDDIGKGKVTLRIFKVTSVDSGSYHCFFKDDKFYEEHIIEVKVTATSSDIQILMHPPNSTGVRLECHSGGWFPQPHMEWRDSKGEYIPATSKSHSQDENEFFNMTMDLFIKSNSYWSAACYIQNFVTHQEESISFVLPGTKVLLLKNIQSIFQSSSVDLEKKDMLLKSIKSRFQSSSVDPEKKERLLKIIQSRIESSSVDQETKALLLESIQSSIENSTVDLETKVWLLESIKSSIQNSSVDPETKELLLERIKSSIENSTVDLGTKEWLLESIQSSIQSSSVDLGTKKMLLKIIQSSIQSFSVYIGTKEWLLERVQSSIQSSSVDLGTKELLLEIIQSSIEGYSVELGIEELLSKIILSSIQSSRVDLGIKELLVKICQSSIQSTSVILETKEWLVKIFQSNIQSSSMDLETKVWLVKFFQSSIQSSSMDLGTIKWLVKNVQSNIQSSRVDLETKRMLLEIIQSSIQNSSVHRGTKKMLLKVIQSSIQSFSVDLETKEWLLKIIQSSIQSSSVDIGTKSMLLKKIGLILRSSIVNPGTELLFQIIQSDLQSSSVNTETREMLFEITQPTVQSSSVNSVTEELLEENYQLLLQSSSVNLEAENILNDTTQRILQLSSVNQGREKLLLDRIQQILQSSSVNPETKCWLLKRIQFILENPSVHQEKKDLLLERIHLILQSSSVQKETKSLLLGSIQSILHSFSVQKETKYLLLEKIQLILQNSSVHQETKDLLLKIIQLILQYSSVHEATSKLLLERIQLILQSSSVQKETKDLLLNRIFSILQNSCVDQGVKYFLLNIIHPILQKTSVHQETKSMLLDRIELILQSSSMQQETKNHLLDQIEQILQDTTVHQETKDLLLNRIELILQNSSVQQETKELLMDKIDSILRYTWVHQETKDLLLNRIELILQSSSVQEETKNFLCNIIASILQSTSMHQEKKKLLLGRIELILQSSSVQQETKKLLLKIVQSSSPSSSVRLESCNKRNPFWKKHALDLGISVFAIIVVTLIRHLNQREADQHFELDTLWSKDTSVILCVLIMFNNRLKALIYFRLYGYSPPGKTYKYIVNYILRFSQPLFFIVYSAIILVMHLQIQNTDSLFSLYNSWMVEMIMVLGLLLAIFNVKNIATALLHLGRTTLRLFRIKD
What is the function of this protein?
May act by engaging a cell surface molecule on immature T-cells in the embryonic thymus.
What are the official names of this protein?
Selection and upkeep of intraepithelial T-cells protein 6, Skint-6.
What is the protein family that this protein belongs to?
Belongs to the SKINT family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PURA_SHEON
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTEQAKYVVRYQGGHNAGHTLVINGDKTVLHLIPSGILRDNVKCIIGNGVVLAPDALMKEINMLKERGIPVEERLLISEACPLILPFHSALDIAREKARGNKAIGTTGRGIGPAYEDKISRRGLRVGDLFNAELFAEKLKEVMAYHNFMLTEYYKVDAVDYEQTLSDALALADYLKSMCVDVTELLDNARKAGEPILFEGAQGTLLDIDHGTYPFVTSSNTTAGGVATGSGFGPRHLDYVLGIMKAYTTRVGAGPFPTELLCEVGDHLGTKGHEFGATTGRKRRPGWLDAVAMRRAVQINSVSGFCLTKLDVLDGLKEVKICVGYQHPDGTISKVTPLAAEGYEQVTPVYETMPGWSESTFGATFLEQLPQAAINYIKRIEELLETPIDIISTGPDRNETMILVSPFN
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_METM6
Sequence: MNILRRGRLGSNVKEDVMKFTTSLEFDKEIFESDILCDIAHTTMLVEQNVISEENGKKIIAELKKIAEQSMESLNLDPSLDDIHMVIESELIKELGEDVAGRMHTGRSRNDEVATDLRLSLRKKVLEIITHLIAMEKNMLRVSREHKETLTVGYTHLQQAQPVTFGHHILSHVSAIERDISRFFDTYNRINISPLGCGAMATTGFNLNRKRTQELLGFYDLIENSMDGVSSRDFVVETMANISMLGTNLSKICEELVVFSSAEFNTIEIANEYTSTSSIMPQKKNPDVAEITRAKLSTLNGELVTVLTIMKALPNTYNRDLQEISPHLWKSVYTLIDSIQMVDGMISTVKVNKERMKENAEKNYSTATELADTLVRECGIAFRMAHGIVGELVKRSIEEKVEIKEIILEVLEKNNLSLSQEKIDTALDPFENVKLRNVIGGPAPKEVERAISSFNEKISSHKEKLDEKIAEIESVKKNLLK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMYL_SHEB2
Sequence: MRAFVLRARSAPTDSQLFLASVGQEAHTEILAHTLMNTIFVAQSHRNDVVVYLVLESTHDFSRTICFDTRNICHIGGFHEQALLTKIAKALDISRGMTKEQTRVVDEGITVSTISFEKLVQDLAVDYQLFMMDKKGTSIREQEFVGNPCFLLTDHIPMPKKSFNTLKRLGAQKISLGPKMLFASQCVVLIHNELDINQ
What are the official names of this protein?
Putative pseudouridine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.