PharMolix/UniProtQA huggingface dataset:
Protein: MYH4_RAT
Sequence: MSSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVVDAKESYVKATVQSREGGKVTAKTEGGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEEAPSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQVMSNKKPELIEMLLITTNPYDFAYVSQGEITVPSIDDQEELMATDTAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKAMYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNTLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIIGWLDKNKDPLNETVVGLYQKSGLKTLAFLFSGGQAAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLKSTHPHFVRCLIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAVCRGYLMRVEFRKMMERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMATMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQIDQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEAIRNLRNTQGMLKDTQLHLDDALRGQDDLKEQLAMVERRANLMQAEIEELRASLEQTERSRRVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRNIEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-4, Myosin heavy chain 2b, MyHC-2b, Myosin heavy chain 4.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: PANB_BACLD
Sequence: MKTKTDFLKMKQEGEPIVMLTAYDYPAAKLAEQAGVDMILVGDSLGMVVLGLDSTVSVTVADMIHHTKAVKRGAKDTFVVTDMPFMSYHCSLESALKNAAAIVQESGADALKLEGGDGVFETITALTRGGIPVVSHLGLTPQSVGVLGGYKVQGKDEESAGKLIEDSRRCEEAGAMALVLECVPAALAERISKELTIPVIGIGAGAGTDGQVLVYHDVVGHGVSRTPKFVKQYAQIDQPLEQALRGYVEDVRSRVFPEDAHSFRIDQQVLEGLYGGK
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDI_MAIZE
Sequence: MAIRSKAWISLLLALAVALSARAEEEPAAAAEGEAVLTLDVDSFDEAVAKHPFMVVEFYAPWCGHCKKLAPEYENAAKALSKHDPPIVLAKVDANEEKNRPLATKYEIQGFPTIKIFRDRGKNIQEYKGPREADGIVDYLKKQVGPASKEIKSPEDATALIDDKKIYIVGIFAEFSGTEFTNFMEVAEKLRSDYDFGHTLHANHLPRGDAAVERPLVRLLKPFDELVVDSKDFDVAALMKFIDASTIPRVVTFDKNPDNHPYLMKFFQSSAPKAMLFLNFSTGPFDSFKSAYSAAAEEFKDKEIKFLIGDIEASQGAFQYFGLKEDQTPLILIQDGDSKKFLKVHVEADQIVAWLKEYFDGKLTPFRNSEPIPEVNNEPVKVVVADNVHDFVFKSGKNVLIEFYAPWCGHCKKLAPILDEAATTLQSDEEVVIAKMDATANDVPSEFDVQGYPTLYFVTPSGKVTSYDSGRTADDIVDFIKKSKETAAPHHHHHPGATGIREGSRAEPVKDEL
What is the function of this protein?
Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.
What are the official names of this protein?
Protein disulfide-isomerase, PDI.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: PTH_PARP8
Sequence: MIKLIVGLGNPGAEYTATRHNAGFWLIDQLAREAGTTLRDERRFHGFYAKARLYGEEVHLLEPMTYMNRSGQSVVALAHFFKILPDQILVAHDELDLPPGTVKLKLGGGSGGHNGLKDISAHLSTQQYWRLRIGIGHPRDLIPDSARAGAKPDVANFVLKPPRKEEQDLIDASIERALAVMPVVVKGELERAMMQLHRNP
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_METMP
Sequence: MLVVKKTPYIKGILSAPPSKSYTHRAVICASLANGLSNLKNPLNGADCLSSAHACEMFGAEIGLGNEKWIVMGSELKTPDNIVDIGNSGTTLRILTGISSQISNGYTVLTGDDSIRKRPMQPLLDALKQLGLICFSTKNNGTAPIVVKSGKISSNVVEIRGDMSSQFITSLMMTLPFSEDDSEIILTTPLKSEPYLNITIDVLDKFGVKIGKIEEKNKSGYKIKGNQTYKPCDYTIEGDYSSASYLVAAGVLLNSDIVIKNVFKDSKQGDREIIEIVKKMGADVEINDDNVKITGPYELNGIEIDVTDIPDLVPTIAVLGCFAKGKTVVYNGEHVRLKECDRLAACTAELSKMGARIEEKKDGLIITGVHKLNGAKLKTYHDHRLVMAFTIAGMLADGETIIEGEDSVKISFPDFVDKMKSIGSNIKVI
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_SYNJA
Sequence: MAAPTYYTITFGCQMNRADSERMAGILESLGYVPAEDELQADLVLFNTCTIRDNAEQKVYSYLGIQAQRKRKNPAIKLIVAGCVAQQEGERLLRRVPELDLVMGPQYVNRLGDLLAQVEAGNQVVATEPVEIPEDITKPRRDSRVTAWINVIYGCNERCTYCIVPLVRGREQSRQPQAIRAEIEDVARAGYREVTLLGQNIDAYGRDLDPKTNLASLLRFVHSVEGIERIRFATSHPRYFTEELIATCAELPKVCEHFHIPFQAGSDAVLKRMRRGYTQERYRQLIQLIRQYMPEATISADAIVGFPGETEAQFQETLQLVQDIGFDFLNTAAYSPRPGTPAAEWPDQVPEEEKSDRLQRLNRLVAEVAAARSARLLGQVQEVLVEGPNPKNPRQAMGRTRGNRIVFFDGDPEQLQGSLVPVRITATRAFSLSGEIVKPGEEKPQAAELGACT
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAB2_HUMAN
Sequence: MHRAPSPTAEQPPGGGDSARRTLQPRLKPSARAMALPRTLGELQLYRVLQRANLLSYYETFIQQGGDDVQQLCEAGEEEFLEIMALVGMATKPLHVRRLQKALREWATNPGLFSQPVPAVPVSSIPLFKISETAGTRKGSMSNGHGSPGEKAGSARSFSPKSPLELGEKLSPLPGGPGAGDPRIWPGRSTPESDVGAGGEEEAGSPPFSPPAGGGVPEGTGAGGLAAGGTGGGPDRLEPEMVRMVVESVERIFRSFPRGDAGEVTSLLKLNKKLARSVGHIFEMDDNDSQKEEEIRKYSIIYGRFDSKRREGKQLSLHELTINEAAAQFCMRDNTLLLRRVELFSLSRQVARESTYLSSLKGSRLHPEELGGPPLKKLKQEVGEQSHPEIQQPPPGPESYVPPYRPSLEEDSASLSGESLDGHLQAVGSCPRLTPPPADLPLALPAHGLWSRHILQQTLMDEGLRLARLVSHDRVGRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPALVEGRRSSVKVEAEASRQ
What is the function of this protein?
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2.  Isoform 2 lacks repression ability (By similarity).
What are the official names of this protein?
NGFI-A-binding protein 2, EGR-1-binding protein 2, Melanoma-associated delayed early response protein, Protein MADER.
What is the protein family that this protein belongs to?
Belongs to the NAB family.
What are the subcellular locations of this protein?
Nucleus. Note=Isoform 2 is not localized to the nucleus.
Protein: METAS_PECAS
Sequence: MPIRVPDELPAVNFLRNENVFVMTSSRAKTQEIRPLKVLVLNLMPKKIETENQFLRLLSNSPLQIDIQLLRIDSRESKNTPTEHLNNFYCNFDDIQDENFDGLIVTGAPLGLVDFCDVVYWPQIARVIEWAKEHVTSTLFVCWAVQAALNILYGIPKMTRKEKLSGVYLHQTLQPHALLTRGFDETFLAPHSRYADFPADVIRQHTDLDILVASEQAGAYLFASKDKRLAFVTGHPEYDVLTLAGEFFRDCDAGLDPTVPVNYFPEDNPELEPKASWRSHGHLLFVNWLNYYVYQITPYDLRKMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_UREPA
Sequence: MNRIKKGDTVVVISGKNKNKSGVVIQVNPKEQTALVEGVNKIKRHQKKDQTHEQSGIIEKEAPIRLCKLALVDPKGKDKGKATKVKYLLKDNKKVRVARKSGSELDVNKK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PR7D1_MOUSE
Sequence: MLPSLIQPCSSGTLLMLLMSNLFLWEKVSSAPINASEAVLSDLKDLFDNATVLSGEMSKLGVIMRKEFFMNSFSSETFNKIILDLHKSTENITKAFNSCHTVPINVPETVEDVRKTSFEEFLKMVLHMLLAWKEPLKHLVTELSALPECPYRILSKAEAIEAKNKDLLEYIIRIISKVNPAIKENEDYPTWSDLDSLKSADKETQFFALYMFSFCLRIDLETVDFLVNFLKCLLLYDDVCYSEF
What are the official names of this protein?
Prolactin-7D1, Proliferin-related protein, PRP.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GP210_ARATH
Sequence: MVPVSFCFFFLLLLLSAGESSSQLVSGPHITDVNILLPPKMKNPVEYRLQGSDGCFKWSWDHHDILSVTPEFNSSSHCSTSARLRSISPYSGRKETAVYATDIQTGMVIRCKVFIDNFSRIQIFHNSIKLDLDGLSMLRVRAFDNEDNEFSSLVGLQFIWKLMPESGGSTHHLAHVPLKESPLTDCGGLCGYLDIQKKLEDSGVFADLFVVKGTKIGHEKVSVHLLEAPLTHIADEIVLTVAEAMSLEPRSPVYVLMGASFGYTLKVMRGNVPQAVDLPSPHHRWSVLNSSVAQVDSLIGLTKALSLGVTTVVVEDTRVAGHIQGSSINVVTPDTLILYISPWSMSGDLITESKPFPSSMHWYVVSGRQYLIQMKIFSGRPDAHEIYITETDDIKLYGKDSDYWKIVSLPDELSSEYGQRNSRILNAISPGLGELTSTLTYFSGHQESKEVLKVVQEIRVCEKVQFTLNSEDDTPKVLLPWTPAVYQEMELIVTGGCAKASSDYKWFTSDISILSVSAYGIIQAKRPGIATVKVVSTFDSQNFDEVIVEVSIPSSMVMLQNFPVETVVGSHLKAAVTMKALNGATFSRCDAFNSLIKWKTGSESFVIVNATSEMMMLDELRSMDSSPPCSRASIYTASTGRTVLQATLAKEFHYFDKSLSESIDLKATLTIGAYLPLSVRQDSDGNHHGGYWFDKAQEETDFGVSKLYLVPGTYVDVMLLGGPERWDDNVEFTETVKTLYEDEEDLTSRVNVHHEVDRRANMYRISCQKLGSYKLVFLRGNLLGIDHPVPAVAEALLSVHCSLPSSVVLIVDEPVNKLDVIRAASQADRAPGRLRVTPVTVANGQIIRVAAVGISEFGEAFSNSSTLSLRWELTSCNNLAYWDDDYNSKMTKSGWERFLALRNESGLCTVRATVSGIDYSFKSQYSTLLPQGSESTLTDAVRLQLVSTLRVTPEFNLVFFNPNAKVNLSMTGGSCLWEAVVNNSRVAEVIRPPSGLQCSQMMLSPKGLGTTIVTVYDIGVSPPLSALALIKVADVDWIKIASGDEISIMEGSTHSIDLLTGIDDGMTFDSSQYSLMDIMVHIEDDLVEHVTVDEDSLSVGEHVATSSFKIAARRLGITTLYVSARQQSGGKVLSQTIKVEVYSPPRLHPQGIFLVPGASYVLTIEGGPTMNVSVDYTTVDNEVAKIEKSGRLYATSPGNTTIYATIYGSEGAVICQAIGNAEVGLPATAMLVAQSDTVAVGHEMPVSPSFPEGDLLSFYELCSAYKWTIEDEKVLIFIASSINVEENAGFVNVVQGRSAGKTRVTIAFSCDFVSPGLYSESRTYEASMILSVVPDLPLSLGAPMTWVLPPFYTSSGLLPSSSEPQKHRDGQSHRGNIVYSILKDCSSRADFERDTISINGGSVKTTDSNNVACIQAKDRTSGRIEIAACVRVAEVAQIRMKSEGIPFHVIDLAVGGELELPINYYDTLGIPFLEAHGVTTYNVETNHRDVVFIKTVNDQPSAYIKGIKHGKALIRVSIGDNLRKSDYVLVSVGAHIFPQNPVIHTGNLLNFSITGADNEVTGQWFTSNRSVISVNVASGQAKAISQGSTHVTFKGHGLKLQTKVTVLFGNTIYVDSPGETLTNVHVPAEGYKFPVKFRENKFAVTEHGNKATFNCQVDPPFIGYTKPWMDLDTGNTYCLFFPYSPEHLVHSMSITKDMKPHVSFSVDASLKEARRVSGSASALLIGGFSVTGPDKLNINPDSNTTIISLVGNTDVQIHCRNKGRLSISLIKRDDFGIAGHAQYKVNVLRSEQFTDRIIITLPATGQIVEIDVCYDTGESLVASSKDGYSVLLKILWGVLVLVVSVIILMKVIDRQVPTGATGTATYSGNAAQGTPERRSGTVIYHEESPRTPSPFMEYVKRTVDETPYYRREGRRRFNPQNTM
What are the official names of this protein?
Nuclear pore complex protein GP210, Nuclear pore membrane glycoprotein 210, Nucleoporin GP210, Protein EMBRYO DEFECTIVE 3012.
What is the protein family that this protein belongs to?
Belongs to the NUP210 family.
What are the subcellular locations of this protein?
Nucleus envelope. Nucleus membrane; Single-pass membrane protein. Nucleus, nuclear pore complex.
Protein: TRUB_SALAR
Sequence: MSRPRRRGRDIHGVLLLDKPQGMSSNDVLQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVQERPVTFSAGQLASALETFRGDIEQIPSMYSALKYQGKKLYEYARLGIEVPREARPITVYELLFIRHEGNELELEVHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLTVSKYPVERMVTLEHLQALAAQAEQQGVPAAQLLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLNGLVRVTEGEDGKFIGMGEIDDEGRVAPRRLVVEHPA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: FEOB_LEPIC
Sequence: MGHSDSSKTFRILMAGNPNCGKSTLFNQLTGLRQKTGNYHGVTVEKAEGIFHHLDHSVKILDLPGAFSLGGSSEDKQITSRVLIGHEAGDRILFVMDASLAERSLQFLLQILELNVPVLVAVTMKDVLEKKRVQLRLDLLSNEFGILFQYVNPKNGEGIKELKDRIVSPKAFCLPIRSFPWDSERENFLNDLLNSLSTEHSNSLKFVLTNSLKELSGEILQKGLPGLSLFSETPSKLIREKFERFGKRFTYLEELTQKSIYIKKILSTAIVGDPIPNERVLSKADKILLHPFWGLVSFLGIMALVFQALFTWSEMPMDWIESCVRNVGTFVGDFLEEGPLRSLIQEGIIGGVGAVLVFIPQISLLFLFIGILEETGYIARASFVMDRFMGKFGLSGKSFIPLLSSAACAVPAIMGTRTIENKSDRLTTILVSPLITCSARYPVYVLVIGAIFPSKNILGIFNVQALTMFGLFLLGMIASMFAALVFKKTFFKSDSSYFLMELPAYNTPSIKSLALTVFKKLKAFLSTAGQIILFISILLWFLANYPRIDSSLYPNLTDAELKKIQIRESYAGHSGKFMEPVLKPIGFDWKMGIGIITSFAAREIMVSTLSIIYGVGGEESTDDLKEALLKDTDENGKPVWGLSNSVSLLLFFAFACQCMSTLAVVKKETNSIFWPLFLFTYMTILAYSTSFIVFQVWQLFS
What is the function of this protein?
Probable transporter of a GTP-driven Fe(2+) uptake system.
What are the official names of this protein?
Fe(2+) transporter FeoB, Ferrous iron transport protein B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEM31_STRCO
Sequence: MTEKALRLGTRRSKLAMAQSGQVADAVSQVTGRPVELVEITTYGDTSREHLAQIGGTGVFVAALRDALLRGEVDFAVHSLKDLPTAQHEGLVVAAIPEREDPRDVVVARDARKLTDLPRGARVGTGAPRRMAQLNAYARTHGMEIETVPIRGNVDTRIGYVRSGELDAVVLAAAGLNRVGRIDEVTDFLSVDTVLPAPGQGALAVECAADNASLIAALAELDDPFTRAAVTAERSLLAALEAGCSAPVGALADLLADGQTVKEMRLRGVVGTTDGSTLVQLSTTGPVPETHEAALALGGELAAEMLAQGAAGLMGERAQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase 1, PBG 1, Hydroxymethylbilane synthase 1, HMBS 1, Pre-uroporphyrinogen synthase 1.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: AAEA_ERWT9
Sequence: MKTLTRKISRTVITLLLVIIAIVLIFRIWVFYTESPWTRDAKFTADVVAIAPDVSGLISEVRVRDNQLVQKDQVLFTIDPPRYQKALDEAQADVAYYQAVMGEKRREAARRNQLGVSAMSREAIEQANNDYQTTEHQLAKAVASRDLAQLDLERTVVKAPSAGWVTNLNVYTGEFITRGSTSVALVKQNSFYVLAYLEETKLEGIRPGYRVEITPLGSNQVLRGSVDSIAAGVTNSSSTVDSKGMATIDSNLEWVRLAQRVPVRIHLDSQPGNQYPSGTTATVVVTGAQDRKDNDMPPLMKLIHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: END4_THENE
Sequence: CHGFDSGYDITKKEGVESLLSEIENLFGLERLKMIHLNDSKYPLGAAKDRHERIGSGFIGEAGFAVFFSFKEVQRIPWILETPGGNEEHAEDIKKVFEIIEKYRIEVD
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RLR24_PLAHL
Sequence: MRSLVWAVIATLIVLTPFSEATSSIASNNEEFKQNVRVASSSLEQKGTIEDSVITRKLQSDSVKKGDSTGLEERGGLHVPTIHDNKIVQGFYKVMRYLRQKLGIDFLLTRLRYGKNGSHQPNMGYSRVDHYH
What is the function of this protein?
Secreted effector that does not suppress pattern-triggered immunity (PTI) in plant host.
What are the official names of this protein?
Secreted RxLR effector protein RXLR-C22.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host Golgi apparatus. Note=Localizes also to host P-bodies.
Protein: MNMG_MYCPN
Sequence: MSFTLTVIGGGHAGLEAAFIASKLGLKVNLLVLDPNHVGSCPCNPAIGGPAKGIVTREIDVLGGMQGKAADATALQYKLLNSSKGPAVQAIRAQIDKIAYQKWFRQQIDQTPNIELIAGEAVDILESNGKVKGVVLADGSELASDAVIVTTGTYLKAKTYCGSLSKEEGPDRAKRSEYLSTNLIKRGFKTLRLKTGTPPRILRESLDFSQMAVEANTTPHLAFSFTTKNYLPLEQQVICHLIHTNPQIHQLILANLKQSAVFNGSIKANGPLYCPSIEDKVFRFQDKERHQIFVEPESLSLETVYLAGFSTSFPPEVQEHIVRLLPGFKNARFQKYGYAIEYDAFSSIQLKSTLETKLIQNLYFAGQINGTSGYEEAAGQGLIAGINAALKLQRKPEFVLQRNEAYLGVMINDLVTKEISDPYRLLTSRAEHRLWLRNDNLQERLIEKSRALGLVEADVYANYLEQQQKKKQLIDYLQTTTVGQIAALKLNFKNTAQTLFDFTKRAEIKLVDLVQLLPKRFDLDVQSLNQIDIDIKYAGYIKKSEKYFKSLNNLSSVKIPLKLNYHKVPNLASEAIVKLSKIRPTDLSVASQVAGINFNDILAIKHFLDNHE
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_HERAR
Sequence: MTKILNINSSVRIGDSISRKVTTEFINKWKAREADAIVVERDLAAQPLPHIDGSTLGAFFTPAEQRTPEQAQIATLSETLVRELFDADVIVIGAPMYNFSITSGLKAWIDHVARAGVTFKYTDKGPVGLLTGKKVYIFTASGGVYSEGPAQAMDFNATYLRTVLGFIGLTDVTIINSEGVAMGAEGVNKALAKTSNTINELLPA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: NEF_HV2D2
Sequence: MGSAGSKKRSERQQGLREKLLRVPERPYGRLSGERREQSSRSPGESDKDLNSPSCEGQNARGAEGGGQQDADESDEDDEVGAICKTPIVPLRPMTYKLAVDMSHFIKEQGGLEGMYYSERRHRILDTYFENEEGIVSGWQNYTHGPGIRYPKYFGWLWKLVPVEVPAATREEEETHCLMHPAQISSWDDIHGETLIWQFDSLLAYDYVAFNRFPEEFGYQSGLPEEEWKARLKARGIPTD
What is the function of this protein?
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Associates with the inner plasma membrane through its N-terminal domain.
Protein: SNAT_SHEEP
Sequence: MSTPSVHCLKPSPLHLPSGIPGSPGRQRRHTLPANEFRCLTPEDAAGVFEIEREAFISVSGNCPLNLDEVQHFLTLCPELSLGWFVEGRLVAFIIGSLWDEERLTQESLALHRPRGHSAHLHALAVHRSFRQQGKGSVLLWRYLHHVGAQPAVRRAVLMCEDALVPFYQRFGFHPAGPCAIVVGSLTFTEMHCSLRGHAALRRNSDR
What is the function of this protein?
Controls the night/day rhythm of melatonin production in the pineal gland.  Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
What are the official names of this protein?
Serotonin N-acetyltransferase, Serotonin acetylase, Aralkylamine N-acetyltransferase, AA-NAT.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. AANAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP74_PARLI
Sequence: MESGPAIGIDLGTTYSCVGVFQNGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPTNTIFDAKRLIGRRFNDSSIQADMKHWPFRVINKDGKPMLQAEYMGETKTLSPEEVSSMVLTKMKETAEAYLGKKVTSAVITVPAYFNDAQRQATKDAGVIAGINVLRIINEPTRAALAYGLDKKLTGEKHVLIFDLGGGTFDVSLLAIDDGVFEVLTTAGDTHLGGEDFDNRLVNHTSLEFKRKYKKDMRTNPRAIRRLRTAAERAKRTLSSSAQANIEVDSLFEGIDFYTSISRARFEDLCSDLFRKCLEPVERAILDAKIDKKKIDTVVLVGGSTRIPKIQKLLQEFLNGKELNKSINPDEAVAYGAAVQAAILSGDKSDEIKDVLLVDVAPLSLGIETAGGVMSKIIERNTRVPTKASQTFTTYSDNQPGVSIQVFEGERAMTKDNNRLGQFELSGIPPAPRGRPKIEVSFDIDANGIMHVTAKDESSGRSNKITITNDSDRLSKDDIDRMINDAERFKAEDDAQRERINAKNQLEGYAFNLKSAVDDAAAQSKLSPGDKETVTKAVNDVLQWLDSNSLADKEEFTYKLEELQKTCSPIMAKMHAGTGGPRGGGPQGFPSGGAGGPTVEEVD
What are the official names of this protein?
Heat shock 70 kDa protein IV, HSP70 IV.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SYR_RICB8
Sequence: MNIFNKLKHDIITASTQLYNNSEIANHASIETPKDSFNGDLSSNIAMIIAAKKNVPPREVALKFKEILNELPYIASIEIAGPGFINFTIKADSWHTAIKDILQNESKFFEIDVDKNKNINIEYVSANPTGPMHIGHARGAVYGDVLANILKKVGYPVTKEYYVNDAGSQINDLVSTVILRYREALGEKITITEGLYPGEYLIPVGQALAKEYGDKLLNMDELERFKIVKNFAIQKMLDLNKEDLKELGVKHDVFFSEQTLHDNGKIEKTVKLLTDMGLIYEGSVPAPKGKVHAEWENRTQELFKSTKYGDDQDRPIRKADGSWTYFASDLAYAKDKIDRGANHLIYVLGADHSGYVKRIEATVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGTFASVQDVNHEVGKDIIRFMMLTRENNKTLDFDLIKVKEQSKENPIFYVQYAHVRTLSILSKAMETIPQSYNSFEAGTYDLSLLSSEEEIEIIKLLASWTKTLETAAKYFEPHRVAFYLINLASKFHALWNFGKENNDYRFIIENNVELTTARLALAKAIQKIIASGLEVIGVEPMTRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_ANADF
Sequence: MLYHFLYPLSGQFGLFNVLRYPSFRIVAAGLVSLLIGLLLGPLFIERMRVLQYGHSNVREDTPERHKKKAGTPSMGGALILLAVTVSTLLFADLGNRLVWAALLVTLGYGVIGFWDDWLKISKRNSKGLAGKKKLVLQVLVVLAVYYGLLTDWQPRTTDGFPFLTIGSLVDLHLTLPFVPTHLFSPSLGWLYLPFMIFVVVATSNAVNLTDGLDGLAIGPTIVSSMTFLALSYVAGATIAGFSLAEYLRIAYIPGAEELGVFCSAIFGAGIAFLWYNTYPASVFMGDVGSLALGGGLGMLAVLTKNEVASAILHGVFLAETVSVILQVWSFRTTGKRIFRMAPIHHHYELKGWAEPKIIVRFWIMSIMLALVALMSLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LFTR_TOLAT
Sequence: MTIYLTELDSTLYFPSPEEALTEPNGLLAIGGDLSPARLLTAYYNGIFPWFSPYQPILWWSPDPRGVLPVAQLHISRSLRKTLNKTSLRFTVNHAFMDVVTACAAPRRYSEDTWITSEFMQSYAVLHEMGQAHSVEVWDNDQLVGGLYGLSVGKLFCGESMFHRQTDASKLALVALCRHLSRYDAPLIDCQMQNSYLETMGVQEWPRAEFLRQLAQLREQSFPAECWQPQVLTL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.