PharMolix/UniProtQA huggingface dataset:
Protein: AHSP_MOUSE
Sequence: MAPFQSNKDLISTGIKEFNVLLDQQVFDDPLISEEDMVIVVHDWVNLYTNYYKKLVHGEQEEQDRAMTEFQQELSTLGSQFLAKYRTFLKSKEPPSNTLPSS
What is the function of this protein?
Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development.  Specifically protects free alpha-hemoglobin from precipitation.
What are the official names of this protein?
Alpha-hemoglobin-stabilizing protein, Erythroid differentiation-related factor, Erythroid-associated factor.
What is the protein family that this protein belongs to?
Belongs to the AHSP family.
Protein: PANB_STAA2
Sequence: MKTVSQLIDMKQKQTKISMVTAYDFPSAKQVEAAGIDMILVGDSLGMTVLGYESTVQVTLADMIHHGRAVRRGAPNTFVVVDMPIGAVGISMTQDLNHALKLYQETNANAIKAEGAHITPFIEKATAIGIPVVAHLGLTPQSVGVMGYKLQGATKEAAEQLILDAKNVEQAGAVALVLEAIPNDLAEEISKHLTIPVIGIGAGKGTDGQVLVYHDMLNYGVEHKAKFVKQFADFSVGVDGLKQYDQEVKSGAFPSEEYTYKKKIMNEVNNND
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC105_MOUSE
Sequence: MPVLLPSTDPGQDSRVGAPEWRQAAKATSRKAHLLTDRCGQEAVTMWQPKDSVLDPNVAHHLGRAAYMEPWRFRVEMLKGGGTLEKPPPGEGVTLWKGKMKPPAWYARLPLPMHRDARAQQTAEVVHAHARGARLTAARLGRAQHQINGQLRLLLRQREATDRRLSEVRKGLLINQQSVKLRGYRPKCEKIPDKADSLLVWEKKELKSMKRKMEKDMEISEDLLKALASCRDTLDFYCQERLQAVELMNQPLDKVLEQAGRHSWVDITRPPTPRTQGLKTPPPDPIGTYTPACAKALFEAKRLLMESKDILTEMAKNEVDIQNQQQEISNRVCSSLAQKMRETLELKERMTMTLGLMRGTIHRCMKFNQEMYVTRGIIKGPLLKRNLEAREKLNRPLVRMYQRHVGTQLPEATRLAQGTDLLTRHNLHMEKNLKELRTTHDNLAWGLNCKKIGHDVDYDVVRLRLRQRHPHVCYEQAQRLVNDWDPPTPARSQTNTASK
What are the official names of this protein?
Coiled-coil domain-containing protein 105.
Protein: YFEO_ECOL6
Sequence: MLHPRARTMLLLSLPAVAIGIASSLILIMVMKIASVLQNLLWQRLPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPIPPSALPGLIVALILGLAGGVSLGPEHPIITVNIALAVAIGARLLPRVNRMEWTILASAGTIGALFGTPVAAALIFSQTLNGSNEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQMEMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVFVLGIGGFILGILGVIGGPVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVALGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVMLPAWLLLAGKPMMMVNRQKQQPPHDNV
What are the official names of this protein?
Putative ion-transport protein YfeO.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEU3_RHOE4
Sequence: MKLAVIPGDGIGVEVTAEALKVLGKLVPDLETTEYDLGARRYNATGELLPADELDQIRQHDAILLGAIGDPRIVAPGILERGLLLNMRFQLDHHVNLRPAQLYPGALSPLAAQPEIDFVVVREGTEGPYTGNGGAIRVGTDHEIATEVSINTWFGAERVVRYAFALAQTRSKHLTLIHKTNVLSNAGAIWTRAIETVGAEYPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDIITDLAGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGKGIADPTAAILSAALLLRHLGREDDAARVEAVVAADLATRGEGPISTTEIGDRITAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_SHEAM
Sequence: MKQYLDLMKHILDKGTDKSDRTGTGTRSVFGYQMRFDLNEGFPLVTTKKCHLRSIIHELLWFLKGETNVDYLHENKVSIWDEWADEKGNLGPVYGAQWRSWPTPDGRHIDQISQVIEQIKATPDSRRLIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLTMMVAQQCNLGLGDFVWTGGDTHLYSNHMEQTQLQLSREPRPLPTMKILRHPESIFDYRFEDFELSGYDPHPHIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1433G_MOUSE
Sequence: MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.
What are the official names of this protein?
14-3-3 protein gamma.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_RICPU
Sequence: MLLSKYFLPVLKEEPSEAQVTSHKLMLRSGMIRQQAAGIYTWLPLGLKVLKNIENIVRLNMNKAGALEVLMPCIQPAHLWMESGRFDNYGKEMLKFQDRHDNTLLFGPTNEDMITDIFRHNIKSYKDLPKNLYHIQWKFRDEIRPRFGVMRGREFLMKDAYSFDINEENAVKTYNQMYKAYINAFRDLGVFAIPVIADNGPIGGNLSHEFHIIAETGESTIYYDKKFKTLKDNPDIDVEEIKSWYAAAEEKYEVNKLPISEQEITSSKGIEVGHIFYIGSKYSVNMNALINDEYGKLTPIEMSSYGIGISRLVAAIIEANCDEKGIIWPSSVAPFKVSLINLNIHDSKCVELAEMAYKELSDKNIEVLYDDTEARPGSKFATHDLIGSPHQIIIGPKKAANNIVALKDRKSGVIEDIEVGSLMSVL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_LEPWE
Sequence: MTMVYANIFLAFITSLMGLLMYRSHLMSSLLCLEGMMLSLFVMMTVTILNNHFTLASMTPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ZDHC7_DANRE
Sequence: MQSSGQRLRDVEQHQPLLSGGEEEVTAGRVWFIQDSCGMVCAFMTWSLVMYAEFVVNFVMLLPSKNFWYTLINGVAFNFLAVLALTSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCSIKPERAHHCSICKRCIRKMDHHCPWVNNCVGENNQRFFVLFTMYIASISLHALCLSGFHFFTCVKVQWNECSDFSPPVAVMLLIFLCLEALLFLTFTAVMFGTQIHSICNDETEIERLKNEKPTWERRVRWDGMKAVFGGPPSLLWFNPFAGLRLRMLMVRARRSGAEFSV
What is the function of this protein?
Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes (Probable).  Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (Probable).
What are the official names of this protein?
Palmitoyltransferase ZDHHC7, Acyltransferase ZDHHC7, Zinc finger DHHC domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CST8_MOUSE
Sequence: MAKPLWLSLILFIIPVALAVGVDQSKNEVKAQNYFGSINISNANVKQCVWFAMKEYNKESEDKYVFLVDKILHAKLQITDRMEYQIDVQISRSNCKKPLNNTENCIPQKKPELEKKMSCSFLVGALPWNGEFNLLSKECKDV
What is the function of this protein?
Performs a specialized role during sperm development and maturation.
What are the official names of this protein?
Cystatin-8, Cystatin-related epididymal spermatogenic protein, Cystatin-related epididymal-specific protein.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YXEM_BACSU
Sequence: MKMKKWTVLVVAALLAVLSACGNGNSSSKEDDNVLHVGATGQSYPFAYKENGKLTGFDVEVMEAVAKKIDMKLDWKLLEFSGLMGELQTGKLDTISNQVAVTDERKETYNFTKPYAYAGTQIVVKKDNTDIKSVDDLKGKTVAAVLGSNHAKNLESKDPDKKINIKTYETQEGTLKDVAYGRVDAYVNSRTVLIAQIKKTGLPLKLAGDPIVYEQVAFPFAKDDAHDKLRKKVNKALDELRKDGTLKKLSEKYFNEDITVEQKH
What is the function of this protein?
Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import.  May transport S-methylcysteine.
What are the official names of this protein?
Probable amino-acid-binding protein YxeM.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane raft; Lipid-anchor. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: H2AXB_ORYSJ
Sequence: MSSAGGGGGRGKSKGSKSVSRSSKAGLQFPVGRIARYLKAGKYAERVGAGAPVYLSAVLEYLAAEVLELAGNAARDNKKNRIVPRHIQLAVRNDEELSRLLGAVTIAAGGVLPNIHQTLLPKKGGKDKADIGSASQEF
What is the function of this protein?
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation (By similarity).
What are the official names of this protein?
Probable histone H2AXb.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL11_RICPU
Sequence: MSQKAIKGYINLIIPAAGATPAPPIGPALGQRKVNIAAFCKDFNDATQGMEKGIPLPTVITVYEDSSFSFKIKTPPAAYFLKKYAKITKGSSSTKKEAVVGKVTMDDCREIAKLKMPDLNTKNIEAATKIICGSAASMGLEVVGN
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: TRMB_YERPA
Sequence: MINDVISPEFDENGRALRRIRSFVRRQGRLTKGQQLALDSYWPVMGVEYQAAPVDLNTLFGREAPIVLEIGFGMGTSLVTMATNNPQQNFLGIEVHSPGVGACLSSAHDAGLSNLRIMCHDAVEVLENMIPEASLDMVQLFFPDPWHKARHNKRRIVQTPFVELVKSKLKVGGVFHMATDWQPYAEHMLEVMSGVSGYLNLSEQNDYVPRPDSRPLTKFELRGQRLGHGVWDLMFERKE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: DNAG_CHLPN
Sequence: MYTEESLDNLRHSIDIVDVLSEHIHLKRSGATYKACCPFHTEKTPSFIVNPAGAHYHCFGCGAHGDAIGFLMQHLGYSFTEAILVLSKKFQVDLVLQPKDSGYTPPQGLKEELRHINSEAETFFRYCLYHLPEARHALQYLYHRGFSPDTIDRFHLGYGPEQSLFLQAMEERKISQEQLHTAGFFGNKWFLFARRIIFPVHDALGHTIGFSARKFLENSQGGKYVNTPETPIFKKSRILFGLNFSRRRIAKEKKVILVEGQADCLQMIDSGFNCTVAAQGTAFTEEHVKELSKLGVLKVFLLFDSDEAGNKAALRVGDLCQTAQMSVFVCKLPQGHDPDSFLMQRGSSGLIALLEQSQDYLTFLISEKMSSYPKFGPREKALLVEEAIRQIKHWGSPILVYEHLKQLASLMMVPEDMVLSLANPQVTAEPQNIPIKQKVPKIHPHIVMETDILRCMLFCGSNTKILYTAQFYFVPEDFKHPECRKLFAFMISYYEKYRKNVPFDEACQVLSDSQILQLLTKRRLNTEALDTIFVQSLQKMADRRWREQCKPLSLNQNIQDKKLEILEDYVQLRKDRTIITLLDPESELIP
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: SYFA_CAUVN
Sequence: MTDLNTLEADVLAQVAAASDLQALDAVRVAAVGKTGSISGLLKTLGAMSPEERKTQGAAINALRDKVQDAITQKKAALEAAELDARLASETLDLSLPAPYRRKGSVHPTMQTMDEVVAIFAEMGFAVAEGPDIEDDFHNFTALNFPEKHPAREMHDTFFFNPKEDGERMLLRTHTSPVQVRTMVSQKPPIRIIAPGRTYRCDNDATHTPVFHQVEGLVIDKGIHMGHLKWTLETFLARFFETDAVTTQFRPHHFPFTEPSAEMDVQCDRSGGEIKIGQGTSWLEILGCGMVHPNVLRACGIDPDEYQGFAFGMGVDRLGMLKYGMPDLRDMWSSDVRWLSHYGFSAFAAPNPASGLS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4025_BACC3
Sequence: MGFPKVERLLINYKTLDEFKKFKGCGAQELSMLEELQANIIENDSESPFYGIYYGGSLIARMSLYMKRNGGEPFEITGTYLELYKLEVLPNFQKQGFGEMLVNYAKGLQFPIKTIARIHSAGFWDKLNFQPVSVPDGDFYVWHPEVNLNTVTNEESA
What are the official names of this protein?
Uncharacterized N-acetyltransferase BCA_4025.
Protein: CWH43_SCHPO
Sequence: MTEKTSSLVFSAQYVALVHTICSFAAFFIPLALALYTHYYQVVKNEFYGYPEEWFPSVSATIGDWYPERSVFQWLIALTATPRLLVLLLWFTLSGISRPSVIITTALGVLRTALCGGWVYVTSTDDHDWHDIFMIGYLISNAPWFILVSKCSPVNSMASRIRNIGSALFVLTIFPLIYWYIQHKFKHIPGAYTVYAFFEWSLILWDILFDSALYWDFKPLVFNLHTSKTYSNPSSFATRKKEKGEHLSYAEAAAVGTQAKNIKKDSNVKCSKKQILFSLLYFSSEVYLSFVFWSVLTSLGLLVWYFPLWHMGISGYEACILFELSPFLLGIPLLRKFASKVPVIFLFLNVIGIAAYKLEDPVHRLFVTAFSVCCECLAWTSLFSNISPENLAIERKISTFLFGLLASSIAKYSFFSNNPIWPILNETNGGKQIPALIVGIIACLIFAIFHVQQTTANAVEHFKLRKITALSAALSLGTVLFCLHTFLCDSTVLMTWSWDGYPIKGPQPYPHGAVSIVVSICAVLVAPYLYQSGAFMLIGFVLACFGSYFMYINHGWCSYLGGLIFTSYVLIYSFASIRISSFYSPAKVWGGAFLVYILYSLAHVWVVAYEFVPGGPILRERTSYILIFIGWNLAALVPAYSGESKEPNKADSSVVDIKQSDSSYRRRSFKKSLLTGFCLALMALKFAIQNMPPYDYTPYHPNEKLFTAGIWTIHFGLDNFMYASENRIRDAVRDMELDVFGLLESDTQRLIMGFRDLTQVLAHDLGMYADYGPGPDKHTWGAALLSKFPIVNSTHHLLPSPQGELAPAIHATLDVYGELIDVVVSHNGQYESQLDRRLQSTELARIMRESPRPLVFLGYVVSNVGQEPQTILTRDTGMLDIEPADYDRWCQYIFYRGVKRIGYARLHRSTITDTELQTGKFLVTKDLGRNVRIDKEHVPESHRYPSLFEGTGVNGHYYDNNLVVHEPWYYD
What is the function of this protein?
Involved in the maintenance of cell wall integrity.  Required for the replacement of the diacylglycerol moiety by ceramides during GPI-anchor maturation (By similarity).
What are the official names of this protein?
Protein cwh43.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PGAP2IP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PTPA_STAAS
Sequence: MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
What is the function of this protein?
Secreted tyrosine phosphatase that plays a critical role during infection as a bacterial effector protein that counteracts host defenses.  Required for intramacrophage survival.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpA, Phosphotyrosine phosphatase A, PTPase A.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted intracellularly upon bacterial infection of macrophages.
Protein: U390_CRYNB
Sequence: MAQGAGKSIKAKGKSGGSQRKNTGKTKPGKREVAPKDRQRVLERSQKKQLSSKINNSIEKQMVQAASVGKLSIMRNVGELESGEGKDGKAKGKGKSR
What are the official names of this protein?
UPF0390 protein CNBD1430.
What is the protein family that this protein belongs to?
Belongs to the UPF0390 family.
Protein: MRJP5_APIME
Sequence: MTTWLLLVVCLGIACQGITSVTVRENSPRKLANSMNVIHEWKYLDYDFGSDERRQAAMQSGEYDHTKNYPFDVDQWRGMTFVTVPRYKGVPSSLNVISEKIGNGGRLLQPYPDWSWANYKDCSGIVSAYKIAIDKFDRLWILDSGIINNTQPMCSPKLHVFDLNTSHQLKQVVMPHDIAVNASTGNGGLVSLVVQAMDPVNTIVYMADDKGDALIVYQNSDESFHRLTSNTFDYDPKYIKMMDAGESFTAQDGIFGMALSPMTNNLYYSPLSSRSLYYVNTKPFMKSEYGANNVQYQGVQDIFNTESIAKIMSKNGVLFFGLMNNSAIGCWNEHQPLQRENMDMVAQNEETLQTVVAMKMMHLPQSNKMNRMHRMNRVNRVNRMDRMDRIDRMDRMDRMDTMDTMDRIDRMDRMDRIDRIDRMHTMDTMDTMDRTDKMSSMDRMDRMDRVDRMDTMDRTDKMSSMDRMDRMDRVDTMDTMDTMDRMDRMDRMDRMDRMDRMDTMDRTDKMSRIDRMDKIDRMDRMDRTNRMDRMNRMNRQMNEYMMALSMKLQKFINNDYNFNEVNFRILGANVNDLIMNTRCANSDNQNNNQNKHNN
What is the function of this protein?
May play an important role in honeybee nutrition.  It is found in the royal jelly which is the food of the queen honey bee larva.  The royal jelly determines the development of the young larvae and is responsible for the high reproductive ability of the honeybee queen.
What are the official names of this protein?
Major royal jelly protein 5, MRJP-5, Bee-milk protein.
What is the protein family that this protein belongs to?
Belongs to the major royal jelly protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDM4B_DROME
Sequence: MKMSEVPRIKVFRPTWEEFKDFPKYVAYMESQGAHKAGLAKVVPPPEWVPRRSGYADLDALNVTIPAPICQVVTGKQGYYQQINIQKKPLTVKQFSELASTERYATPKHFDFEDLERKYWKNITYVAPIYGADVSGSITDTDQDSWNINRLGTILDYVNKDYNIQIDGVNTAYLYFGMWKTTFAWHTEDMDLYSINYLHFGAPKTWYVVPPECGRKLEKVANQYFPASYKNCNAYLRHKMTLISPQILKQHDVPVSKITQEAGEIMITFPFGYHAGFNHGFNCAESTNFAMERWIEYGKRAVQCTCSNDMVKISMDTFVKRFQSDRYDLWMEGRDVGRHPEDPPNAVLSAAPLPPHLDVLLCDKKMKKQCNPTKAKSFKERNPDLDLDEIQQNPNVPDDVKAMLKESVLTLDTGDLATDEADFPNEDAMSLQSPANLKTKQELLEYIDDGTEDDDEEEDFKRRKQKRRYDADYDDDWLASKRKTNSRNNRGRSPRTKDDRSISPASSTSSTSRGARRGKASGTPRKTPARRKKDSITTSPAVSSAATAVKTPTSAVVAGTTSIATTTTPPADGGGGESSSLGSHCTTASP
What is the function of this protein?
Probable histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code.  Demethylation of Lys residue generates formaldehyde and succinate (By similarity).
What are the official names of this protein?
Probable lysine-specific demethylase 4B, Probable JmjC domain-containing histone demethylation protein 3B, Probable [histone H3]-trimethyl-L-lysine(9) demethylase 4B.
What is the protein family that this protein belongs to?
Belongs to the JHDM3 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPY_ECOLI
Sequence: MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKFGPHQDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKVKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATAE
What is the function of this protein?
An ATP-independent periplasmic chaperone, decreases protein aggregation and helps protein refolding.  Binds substrate over a large region of its convex inner surface (PubMed:21317898, PubMed:24497545).  Substrate protein folds while it is bound to chaperone (PubMed:26619265).  Increasing Spy flexibility increases its substrate affinity and overall chaperone activity (shown for 3 different substrates) (PubMed:24497545).  Protects proteins in vitro against tannin inactivation; tannins have antimicrobial activity (PubMed:21317898).  Overexpression enhances the stability of otherwise unstable periplasmic proteins (PubMed:21317898).
What are the official names of this protein?
Periplasmic chaperone Spy, Spheroplast protein Y.
What is the protein family that this protein belongs to?
Belongs to the CpxP/Spy family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL9_CAMFF
Sequence: MKVLLIKDVKGLGKAGEVKDVKDGYGNNFLIGKGLAKSATDAVLKQYEAAKKRAQEEINYEINQNEKLKAELENIKIIIKTKLGANGALFGSITKDEIANALKEQKGYEVDKKALECDHIKATGIYDVALKLKHGISAKFKVEVAGE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YET2_YEAST
Sequence: MGVYLAVLFSLLVIEMAILFILVLPLPQRMRRWLYIRYSIISTNKKFRTYMVGIMIFVGLLFIDSWKRSQIRVSTYRNQKNPYIINSVTPVDALASRAYNQRNVYISGFIIYFYICILTVMSILRRIVEWNDKMKAGDDILKEKLRRKQKYLEELQKKKF
What is the function of this protein?
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
What are the official names of this protein?
Endoplasmic reticulum transmembrane protein 2.
What is the protein family that this protein belongs to?
Belongs to the BCAP29/BCAP31 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RK4_TRICV
Sequence: MTVQKFITYNSVDINGKTLSDEYKLELNVLEKSGNYLIHKDILRHQSSQRQGTISTKTRSEVRGGGRKPWRQKGTGRARAGSSRSPLWKGGGVIFGPKPRKIILKLNKKERKLALQTLLYNKRNNISIIDNLETNLDLPKTKTFYSLCKNCEINLDQKILIIVGEKTIPLKLATRNIKNVELILASNLNTFSLLKAKQILMTPLAVKDIKEIYCG
What is the function of this protein?
Probably binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRMB_CUPNH
Sequence: MLPQDPSTEPTPADDAAPVDSAGQASAPSPADPEGVAHPRRIRSFVRRAGRTSTGQQRAIDEVGPRMMVPYAPQPLDWEATFGRKAPSILEIGFGMGETTAHIAGLRPQDNFLGCEVHEPGVGALLKLIDERGLANVRILQHDAVEVIAHMLTDDCLDGVHIYFPDPWHKKRHNKRRLVQPPLVKVLAARLKPGGYIHCATDWEEYAHQMLEVLSGEPLLENTSTAADGFAERPDYRPVTKFERRGVRLGHGVWDVVFRKRAA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RNZ_LACLA
Sequence: MEIQFLGTGAGQPSKSRNTQAIALKMLDERNEIWLFDCGEATQHQILNTTIKPRKITKIFITHLHGDHIFGLPGFLSSRSFQSSDEQTDLELYGPVGIKDFVLTALRISGSRLAYRINFHEIDSAGKIFEDDSFEVHTDLLDHTIFCLGYRVVEKNRIGELDANALKEAGLPFGPLFGKIKKGEIVQYEGKTFDPKDYIGADKAGKIVTILGDTRKSNVAVRLAYGADLLVHEATYEANESKMAKAHGHSTTKQAADVAKEAGVNRLLLTHISARYVGPLVGQLVREAQTVHSNTFVVKDFYEEKIG
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: PDYN_PIG
Sequence: MAWQGLLLAACLLVLPSTMADCLSGCSLCAVKTQDGPKPINPLICSLECQAALQPAEEWERCQGLLSFLAPLSLGLEGKEDLESKAALEEPSSELVKYMGPFLKELEKNRFLLSTPAEETSLSRSLVEKLRSLPGRLGEETESELMGDAQQNDGAMEAAALDSSVEDPKEQVKRYGGFLRKYPKRSSEVAGEGDGDRDKVGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQEDPNAYYEELFDV
What is the function of this protein?
Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
What are the official names of this protein?
Proenkephalin-B, Beta-neoendorphin-dynorphin, Preprodynorphin.
What is the protein family that this protein belongs to?
Belongs to the opioid neuropeptide precursor family.
What are the subcellular locations of this protein?
Secreted.