PharMolix/UniProtQA huggingface dataset:
Protein: MUTL_GEODF
Sequence: MATRIKILPEQLTNKIAAGEVVERPASVVKELVENALDAGCSEVMVEIEAGGKRLIRVSDTGCGMTREDALLALERHATSKIANDEDLFSLATLGFRGEALPSVASVSRFTLATREKGSLEGTEIYAEGGRIKEVKACGMAEGTVISVRNLFFNTPARLKFMKSSETEAGHVGDLLTRLAISRPDIRFIYTNDGKTVFRALNADLRERVATLLGRTLSQDLYPLDFCDGQLNVTGLVGKPECSRSAASHVYTYINGRFIRDKVVQHAVLQAYRNFMERGRYPVVVLFISVPAAEVDVNVHPTKHEVRFREQGRVHDAIQEAVESVLRSSPWVKTQPVVQKTQASTSIAAARIAQVRESLTQYRPQKTTQQSFKMSTPAVPASFRETSLPDPVPVADAAPAPEVERGYFSGLSVIGQFNAAYILCQDGNSLVIIDQHAAHERVAFERLKTQHAAMGVESQRLLFPETVEFSFKEGAVIREHQTELDRVGFSLEEFGGSTWLLNAVPHLLSGNDYVKTLRDILEELQSLGRSRSFQDILEDILARIACHSVVRGSHCLSQQEIKALFQQMDTTEFSSNCPHGRPVLHTLTLAEIERMFKR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: CCMC_ECOLI
Sequence: MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFAPADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFIGLVWQMKMANLAVAAMAPIGAVFTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAGILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSIFGFLLLSATLTLMRMRNLILLMEKRRPWVSELILKRGRK
What is the function of this protein?
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
What are the official names of this protein?
Heme exporter protein C, Cytochrome c-type biogenesis protein CcmC.
What is the protein family that this protein belongs to?
Belongs to the CcmC/CycZ/HelC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CRBN_DROGR
Sequence: MDGEEAADIDETNSSNPHAAAVVATEMQAVAEAERPEEQQQQQMPQTSSGEADGDVDGDGVSAIAALATRVRLENMLEVVDNMFDEVSELMVDVTELMQRASELTGTTTPTPTAPENQAENAPEIEPAQPATPPEIAELLEEAIAANPLGHNVLNPGDDARSISSRHSGSDMSLDSPGSEDDSDAEAVPRWIIPENRVRSAVDMLVSQARNQDGGIATLLRRENFLQRVRSMVFSQDRVRGRESDEANLDAGNVVDEELSPELSPAPLDIDMEEGVRFDTNLPAEHSYFGPNLNRVPGVDYLEVGSTHRMLIFMHQHILFPGEVLPFMIDGSIIDEEIHDTGRDGVIFGVGFPLMQPPDDNPHKLYGVTCQIYEKGESGRQMVFYKSRALQRIVINCDDIQGPPQYIARNPTMKCYSKVKVLPEYFLPEPLKCIDMGSLNRFRDLPSMQDKFRRYQLTSTPWPLEACEEYSFEHIVEMARKKLEVHKIDTMPKCPIQLSYWLVRNLHLTEKMMRLTFLTDSVNTRLQIIGSTLKQESLFYCRYCNSSLAYCSDLFAMSKHGVQTQYCNSAGYIHETNTVYRIIAHAVGYSGEPSTEFSWFPGYQWHIIICKFCAQHVGWEFKAVDPNLAPKVFFGLAGSSVRIGKTSERTPTQGNPFVVRNLLHLVFREIE
What is the function of this protein?
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Has an essential role in mediating growth by negatively regulating insulin signaling.  It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae.
What are the official names of this protein?
Protein cereblon, Protein ohgata.
What is the protein family that this protein belongs to?
Belongs to the CRBN family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAA_ROSS1
Sequence: MNLTKVWNTTLGSLQVQLPRHEYNTWVRGATLLEIDNGVAIVRAPNAFIKEGLESRYLATLREQLGSVVGFPVDVRVVLASPDFERFDGAPHNGRSTENETRRTAQSLPLQPGSSSNGVNHPLERTPPQQLELHRAVRSSMLNPRYTFDRFIIGPSNRLANAACMAVAEHPAQAYNPLFLYGGVGLGKTHLLHAIGNFVLDRDPEVNVLYVSSETFTNDLINSIRRQQTEEFRIRYRNIDILLIDDIQFIAGKEQTQEEFFHTFNTLHSAGKQIVISSDRSPKAILTLEERLRSRFEWGLIVDVQMPDLETRTAILRAKAEQSPVPVPQPVIDFLAQRIQSHIRELEGCLNRVTAFAQMYNVPVTIEVATAALSELLDTNRRKRVTPDAILREVAAFYSVDLRALQGRSRSRNIVIPRQVAMYLLREETDSSLMEIGQLLGGRDHTTVMYGCEKITEELNSDARLRQEVATIRERLLHSAG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHR_MOUSE
Sequence: MENDTVSEMNQTELQPQAAVALEYQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELEDITVTDTYVSTTKVSFDDTCLASEN
What is the function of this protein?
Receptor for thyrotropin-releasing hormone (TRH).  Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
What are the official names of this protein?
Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS4_BIFAA
Sequence: MSLTLLPAVDVRDGKAVRLRQGESGSETDYGSPLEAARTWVESGAEWIHLVDLDAAFGTGNNRDQLRAIVKELGDKVNIEMSGGVRDDASLDAALEAGAARVNIGTAALENPDWTASVIKKYGDRVAVGLDVRGHTLAARGWVKEGGDLFETMKFLDSVGCSRYVVTDVARDGMMSGPNIELLREVASRTDAKVTASGGISKLDDLRNIKELAELGVDAAILGKSLYARAFTLEEALEVAR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEY1_PHANO
Sequence: MMMNSHFAGVGDNVDKEAYGHGIQVVDEDKVFNNNLSTYLNIEKVIPAGFNYHLISVFGSQSTGKSTLLNYLFGTQFGVMAEQERRQTTKGIWMSKNKRPEGGSAMAENILVMDVEGTDGRERGEDQDFERKSALFALATSEVLIVNIWEHQVGLYQGANMGLLKTVFEVNLQLFIKDSKTIPKSLLFFVIRDHLGTTPLKNLQNTLTQDLSKLWSTISKPKGLENSRIEEYFDFAFVALPHKILQPEKFEEAVTKLSLRFKEGYNDPKTSGLVDEAELPIFQPQYHRRIPADGFPAYAEGIWDQIVHNKDLDLPTQQELLAQFRCDEISREVLVLFDETIAPLEEKQAEDTRMGKPSVIAELGAAMNAARSTVFKDFETNASRYHKGVYKRKQAELEGKVDTRLKALSQKQLNAAHKSGVESFSDAVSAAVKAGQKKGASYDFAQIVDSEKKKAIAQFGEQAKSIVIEGASWSSFEHELKVYRKDLDDVSGRLRKDEMRRLATRIERWVRSRLDESVGLEFNKLGTGRGGSGAPEHGERPPSEKDLWDRVWAIFTETVSSAEKRFTDRAQSFDASPEEVDVGLWRLRRKSWGVLRAKIDEEVMEGNILLKLRENFEDKFRYDEQGVPRIWRPTDDIEGIYTKARESTITVIPLLARFKLSKTSAPPPLDAWIGDAPASVTPADEEDLTPIGGLDEEEGKSLEEEMTVLSDAKQADLLIRFKKTADGVYVEAKRSAIGGITQVPLYFYGLLVALGWNEIVAVLRNPVYFIFLILCAVGAYVTYTLNLWGPMIRMGNAASAQALEVGKERLREFLESSESGRQAMAMSGNQPRGESVRMNRLNGNGKKDEDAEVEDLDDI
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: GNTX_SALTY
Sequence: MLTVPGLCWLCRMPLALSHWGICSVCARAVRQRVSLCPQCGLPAAHPSLPCGRCLQKPPPWQRLVSVSDYTPPLSLLVHQLKFTRRSEIAAALARLLLQEVLMARRSTGLQLPDRIVSVPLWSRRHWRRGFNQSDLLCQPLAHWLGCAWDSQTITRVRATATQHHLSARLRKRNLKNAFRLELPVQGLHMVIVDDVVTTGSTVAEIAQLLLRNGAATVQVWCLCRTL
What is the function of this protein?
Could be involved in gluconate metabolism.
What are the official names of this protein?
DNA utilization protein YhgH, Protein GntX.
What is the protein family that this protein belongs to?
Belongs to the ComF/GntX family.
Protein: OBG_CUPTR
Sequence: MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAVADRNINTLIDFRYAKKHVARNGENGRGSDCYGAAGEDITLRMPVGTLITDMDTGEVIADLTEHGQRVCLAEGGMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISHISNARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGLLLHIVDLAPFDEAVDPVAEARAIVNELKKYDETLYEKPRWLVLNKLDMVPEDERAAKVKDFLKRYKWKGPVFQISALTGEGCRELIYAIKDHLQAIKAEEAAALAEPDIRLDDRLHNVDQDQREA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHAA1_NOSS1
Sequence: MSIVTKSIVNADAEARYLSPGELDRIKSFVAGGQQRLRIAQALTDNRERLVKQAGDQLFQKRPDVVSPGGNAYGQEMTATCLRDLDYYLRLVTYGIVAGDVTPIEEIGVIGVREMYKSLGTPIEAVGEGVRALKNAASTLLSAEDAAEAGSYFDYVVGALQ
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 to 653 nanometers.
What are the official names of this protein?
Allophycocyanin subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the core of the phycobilisome.
Protein: ANT1_ONCVO
Sequence: MEKAREGAPSKERRSAEETISRETRHEIAGNDGDIGTDNIEYIDSMDSTGLGYGRTGEGISRILYEHPRDELINYKRRIDANTEQQREHADIMAALQRKIEEYRRRFAEIEGRLVVHDLNESGDLVNMKLKEEWLLSPKIKMEEISDVDFPNQLEDERRRAEDLAIQLQQERLQNDQLQSEIQRLRQQFGICIRDKERIYQTRERNFTRFLGEEQRKMMELWSELQRVRKQCAEYREQTERDLENQRNEFIKVIRHVSGIVRGLNIENGTHTLLSDLSSESGVEITQDTVLIEAVKRFHESQQQTAPVIGPELITELRLARAEDAGLHDELMRKYEESAKRIIELEARDDESHNKLVALESDLKRTRDRLAESQNALRKLYDMTYSYEINAEKETRSPSPTKGYVPPPEVVRSVRYVLNSRANDNNVLQRKLKNAEVQISELTTKNDSLEEIRRRLEKRIAEANRTITHRQRELDDAKHTVKDLEDRLKSLEQEKASIDSARHHLEDEIRKMREQFNSTLLDVERRAAEDADERIRKIDEETKIRISELTNRIEMLLEENKRLKDENDGMKNRIQDIEKEYNTIIRKLEEKDNALKNLENTRQRLVNELEEQRTRFDTMTSEFDNLRTNYDSANKNTVAIELTVKQIKEQRDEIIKQKDKLAKELADLENKLNNETKMRGDAEKLNQRHLDEIDNFKKQINEYITEVTIIRRQNDDFDTQMKTNQAKLSSMKNSLIAAKKEIEKLSEMNNRLQQDKNDLIGAKQKGDTELNLLTEKIRKVEIEFERIKKDNQELEDHERTARDDLKQETNRNHLLAKELEEARADIVALNDRLAKMDANFKIKLDETIKKSPADHETIKSRESKSEKIIVKHETKIYEINKYRAELEKLESDKDDLEKRIIGLQDELNEKDRDTDRLNAEIDDLKRKLQTEIEKVRKETTTVQERYHIEWDEERDNHQKKIDSMNALIDELRSKLNDAERAMADLQNRDSILERENNDWKEKSDALNMELDRLRDELLSVRRDAEKEINRYNTDLQTAARNEIKLLTPTNNEMKSQLNAAEDKINSLNKVITDQQNKIRDLTGEVHHLEGELKDAKGNVANLESELDTTRERIHLLGEQNASLQTELNKIKGDIDSLFGENDMLKTAKESNEAEIDRLKQKLQRSIENAKKYSDALDKLRPEYDRLQNLYREKIKQAENLTQAVQDLESRLNQSRRELRDATDKLIASEGDRNALRSEVEKLQHEVQFMREQLLRKTDEYQAALSDLVNAHRTAEDGRVNAVQALEARKYEINDLQSRLDNAEQYLVTLQQNYVAVENERDMLYDALRRLHSMIDRTVTINRFLIGVDESMDEKKETVLQTQKSPDGKSKERFDISDLDTNIQKLIGRIEKLELERNEYRDALDRIKKKSIESHIKINKQETIFTNIEDQLVDVEEEKRTLEMRLASAKQLLRSQEEALKQRDEERSHMKLKIAKFEMEARGKEAQLRQLNELVRNLRKDLETAQGDLGVLHDHEERWYAHKFHLESKLKDQESESQQIRLLVANFETERNSLNEKVRDLASRLQQTESKNADMKEDNDRLKKDLIKASTNEAELRRTIDQNSRVVSDNQILKDQLESAQNDLSNANNRKQQLENELLVVRSELRDLKQRFSDNANRIIDLQRHLTDAENDKKRLTNRLNSLEKTVSQQRTIETEIRQQLSLALNERNTLQNDLRDLQRRLARMETEKKIMNDKYDELEKIRASLIKRIELLDEEKRTMENILHETALQREAIESSLNALERENKELHRNCAQLQQQIAQLELENGNRLIQLTNKQREEYDKFAQNMRTEKIQIERIIENRERSLKSRINQLENQLNIMRDQLNSERRRRREISDKILSGEVNKLNVTLSGIPDAYEMYDRTLYTYNTYFGSPSFTVGSSSFDPNITDDSKIILKHSDRLESSYAYGGGNRTSDTAVTAPTGSSSYHGQRSDTHTVNESERGGNDSGKGTKQVDGEGGSLSLSEIGQGATFEQQQQRRRKRQ
What is the function of this protein?
May be a myofibrillar protein.
What are the official names of this protein?
Major antigen, Myosin-like antigen.
Protein: NFUA_SHEPW
Sequence: MITISETAQAHFVNLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTELEFNGFNAMVDEKSAPFLEEATIDFVTDQLGSQLTLKAPNAKMRKVSGDAPLVERIEYVIQSEINPQLASHGGNIMLVEITEDGIAVLQFGGGCNGCSMVDVTLKDGIEKQLLDMFPGELTGVKDVTEHQHGDHSYQ
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: DAPA_CHLCH
Sequence: MPTPYLSGSAVALVTPFKSDSSIDFEAIARLTEFHVAAGTNIIIPCGTTGESPTLAEEEQVAIIKTVVEAAQGKLMVAAGAGTNNTHHAVELAKNAEKAGAAAILSVAPYYNKPSQEGFYQHYRHIAEAVAVPIIIYNVPGRTGCNVAASTILRLARDFDNVLAVKEASENFTQISELLEERPSNFAVLTGEDSLILPFMAMGGNGVISVAANEIPAQIRQLVESAGSGDLVTARTLYSRYRKLLKLNFIESNPVPVKYALARMGMIEENYRLPLVPLSAESKRAMDEELTLLGLV
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_HYDS0
Sequence: MDVLEIMKIIPHRYPLLLVDKILEMELGKRIVGLKNVSVNEPFFQGHFPGYPLMPGVLMLEAMAQVGGILMIKSLGLEIGKYAVVFAGIDEARFKRPVYPGDQLIMELETISLKKTISKMKGTATVNNQVVAEAILMAAARELESIKK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTH_SHEB8
Sequence: MNRIIPPENLPELLERAHMMAGVSLAQIAAQRGLSVPKDLKRDKGWVGQLIEMELGATAGSKPEQDFLHLGVELKTIPIDSQGRPLETTYVCVAPLSNIQGLTWQNSLVCHKLQRVLWVPVEGERHIPVAERRIGTPILWEPDPQELQLLQQDWEEIMELIALGKVEKLTARHGEVLQLRPKAANSKALTQSIAEDGSLKMTNPRGFYLKTSFTAMILNKVFG
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCFD2_RAT
Sequence: MASLQLLRGPFLCVLLWAFCVPGARAQEHGAGVHHGSVGLDKSTVHDQEHIMEHLEGVINQPEAEMSPQELQLHYFKMHDYDGNSLLDGLELSTAITHVHKEEGSEQVPPMSEDELISIIDGVLRDDDKNNDGYIDYAEFAKSLQ
What is the function of this protein?
The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
What are the official names of this protein?
Multiple coagulation factor deficiency protein 2 homolog, Neural stem cell-derived neuronal survival protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus.
Protein: MB3R2_ORYSJ
Sequence: MGAMAMVEQEGCVENRQPLAASSSSVSDGSSYGGGGGGLAQMSPPVSSSANSISGLRRTSGPIRRAKGGWTPEEDETLRKAVEAYKGRNWKKIAECFPYRTEVQCLHRWQKVLNPELIKGPWTQEEDDQIIDLVKKYGPTKWSVIAKALPGRIGKQCRERWHNHLNPEIRKDAWTTEEEQALINAHRIYGNKWAEIAKVLPGRTDNSIKNHWNSSLRKKQDMYNTSNNMVVPKLLVHDKFKDKPKLMAMEGHLDLNKAPIINSKDQPGTAHRSNCSGFLSRSSLPTAQPLTSREASVVDGSAVTLVAQALESDSVRGKGLEIDSVHEKGLEVNSAPDHTGNSWTIQLEAAPSKGEAELSLKNEARSLGPLCYQIPNMEDVVPVSSSLFSDHLTGNHTSEHCGDDILSPAGCTTPPPTKGKLTSQLSVDSILKSAANSFPGTPSILKRRKRDKSTPVSASEMKISGSNTDRFYTPMGMEPATATPESFKTTSFLSLGSLDGSVKSFDVSPQYRARSKRMALTKTVEKQLDFSSDGLDTCGSEILNSSCNNSQSTLSITEAPKLKEKEHAVQLENLTKNFAHTTNLDVT
What is the function of this protein?
Transcription factor involved in abiotic stress responses (PubMed:17293435, PubMed:19279197).  May play a regulatory role in tolerance to salt, cold, and drought stresses (PubMed:17293435).  Transcriptional activator that binds specifically to a mitosis-specific activator cis-element 5'-(T/C)C(T/C)AACGG(T/C)(T/C)A-3', found in promoters of cyclin genes such as CYCB1-1 and KNOLLE (AC Q84R43).  Positively regulates a subset of G2/M phase-specific genes, including CYCB1-1, CYCB2-1, CYCB2-2, and CDC20. 1 in response to cold treatment (PubMed:19279197).
What are the official names of this protein?
Transcription factor MYB3R-2, Myb-related protein MYB3R-2, OsMYB3R-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: OTC_VIBCM
Sequence: MAFNLRNRNFLKLLDFTPKEIHFLLDLSAELKRAKYAGTEQKTLQGKNIALIFEKSSTRTRCAFEVAAFDQGAQVSYIGPSGSQIGHKESMKDTARVLGRMYDGIQYRGFGQEIVEVLGQYAGVPVWNGLTDEFHPTQILADLLTMQEYGRSKQLHEMKFAYLGDARNNMGNSLMVGAAKMGMDIRLVAPKAYWPNDALVATCQEIAKQTGAKITLTEEVQEGVKGCDFLYTDVWVSMGEAADAWDERVALMKPYQVNMDVIKATGNPQVKFMHCLPAFHDDQTKVGQEIAAKYGMQGLEVTEEVFESEYSIVFDEAENRLHTIKAVMVATLGQ
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_NITHX
Sequence: MKAEIHPDYHTIKVVMTDGTEYMTRSTWGKDGDTLNLDIDSKSHPAWTGGSQQLLDRGGRVSRFQKKFSGFLKKD
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ERPA2_POLNA
Sequence: MEAALNIASPSLPGVMPGQLEFTTSAAAKVSELIVEEGNPNLKLRLYVTGGGCSGFSYGFAFDDQTAEDDTLIVTEGVALVVDAMSLQYVLGARVDFEDGLEGSRFVIHNPNAQSTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA 2.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: PEF1_RAT
Sequence: MASYPDGQSYPGAAGQVPGPHPGGYYPGPPHGGGQYGSGFPPGGYGAPAPGGPYGYPSAGGTPSGTPGGPYGGGPPGGPYGGGPPGGPYGQAHPSPYGTQPPGPYGQGGVPPNVDPEAYSWFQSVDADHSGYISLKELKQALVNSNWSSFNDETCLMMINMFDKTKTGRIDVVGFSALWKFLQQWKNLFQQYDRDHSGSISSTELQQALSQMGYNLSPQFTQLLVSRYCTRSAIPAMQLDCFIKVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTASRML
What is the function of this protein?
Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium.  Together with PDCD6, acts as calcium-dependent adapter for the BCR(KLHL12) complex, a complex involved in endoplasmic reticulum (ER)-Golgi transport by regulating the size of COPII coats.  In response to cytosolic calcium increase, the heterodimer formed with PDCD6 interacts with, and bridges together the BCR(KLHL12) complex and SEC31 (SEC31A or SEC31B), promoting monoubiquitination of SEC31 and subsequent collagen export, which is required for neural crest specification.  Its role in the heterodimer formed with PDCD6 is however unclear: some evidence shows that PEF1 and PDCD6 work together and promote association between PDCD6 and SEC31 in presence of calcium.  Other reports show that PEF1 dissociates from PDCD6 in presence of calcium, and may act as a negative regulator of PDCD6 (By similarity).  Also acts as a negative regulator of ER-Golgi transport; possibly by inhibiting interaction between PDCD6 and SEC31 (PubMed:27276012).
What are the official names of this protein?
Peflin, PEF protein with a long N-terminal hydrophobic domain, Penta-EF hand domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein. Note=Membrane-associated in the presence of Ca(2+) (By similarity). Localizes to endoplasmic reticulum exit site (ERES) (PubMed:27276012).
Protein: RRP3_CANAL
Sequence: MTMMNEKLKKEKKKIFGVITPFQKYLYTPRIINTVHLIIMSSKGITKKKVKSLKNLDSTKKLAEKIKQQALQKQQKQQKQQEQENANHNQTESSLSSSSSTTSSSITTIDPDAELKFKTFKELNLVPDLLESIESMKFTKPTPIQSEAIPHALEGKDIIGLAQTGSGKTAAFAIPILQSLWHAQQPYFALVLAPTRELAFQIKDTFDALGSSMGLRSSCIVGGMDMMDQARDLMRKPHVIVATPGRIMDHLEHTKGFSLKNLKYLVMDEADRLLDMDFGPALDKILKVIPIKRTTYLFSATMTNKIEKLQRASLHNPVRVAVSSKYQTADNLVQSMMLVNDGYKNTILIHLLNEFMGKSIIVFTRTVAHAQRTALLARILGFNAVPLHGQLSQSQRLGSLNKFKSNQANILVATDVAARGLDIPSVDVVINYDIPTDSKAYIHRVGRTARAGRSGKSISLITQYDLEMYLRIESVLGKKLPKEDKPPKEVLDALHVHVDKATAEAIRQTKEIHDKRNGGGGRRRNRDDADREER
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase RRP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TDH_YERPN
Sequence: MKALSKLKAEEGIWMTDVPQPELGHNDIMIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVAIGQEVKGFNIGDRVSGEGHITCGHCRNCRGGRTHLCRNTVGVGVNRPGSFAEYLVIPAFNAFKIPDNISDELAAIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAVCKHVGARHVVIADVNEYRLDLARKMGVTRAVNVSKENLNDVMTELGMTEGFDVGLEMSGAPPAFRSLLNSMNHGGRIAMLGIPPSDMSIDWNQVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLTPIITHRFPIDEFQQGFDAMRSGKSGKVVLSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPM2_MOUSE
Sequence: MSRHSTSSVTETTAKNMLWGSELNQEKQTCTFRGQGEKKDSCKLLLSTICLGEKAKEEVNRVEVLSQEGRKPPITIATLKASVLPMVTVSGIELSPPVTFRLRTGSGPVFLSGLECYETSDLTWEDDEEEEEEEEEEDEDEDADISLEEIPVKQVKRVAPQKQMSIAKKKKVEKEEDETVVRPSPQDKSPWKKEKSTPRAKKPVTKK
What is the function of this protein?
Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development.  Probably involved in sperm DNA decondensation during fertilization.
What are the official names of this protein?
Nucleoplasmin-2.
What is the protein family that this protein belongs to?
Belongs to the nucleoplasmin family.
What are the subcellular locations of this protein?
Nucleus. Note=Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.
Protein: LSHB_BOVIN
Sequence: MEMFQGLLLWLLLGVAGVWASRGPLRPLCQPINATLAAEKEACPVCITFTTSICAGYCPSMKRVLPVILPPMPQRVCTYHELRFASVRLPGCPPGVDPMVSFPVALSCHCGPCRLSSTDCGGPRTQPLACDHPPLPDILFL
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin subunit beta, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta, Lutropin beta chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.