PharMolix/UniProtQA huggingface dataset:
Protein: SUCC_IGNH4
Sequence: MNLLEYEAKAIAKKYGIPTPEGVLIERPEQVNEAVEKLGLPVVLKAQVPVAGRGKAGGVKLARDPDEALELAEELFSKEIKGFPVLSLLVEKAENIQKELYLSFTIDRTNRKVVMLASAEGGMEIEELAKEKPDAIVKLPIEPEVGLKAHEAREVGKRIGLSGQLLRQFEGIAKTMYKIFEDYDAELVESNPLAITDRGLVALDFRMIVDDNAIFRHPELEASRERELSELEKEAARWGFFYVELDGDIGIIGNGAGLTMATMDVVNYYGGRPANFLDIGGGARRDRVKAAVNVLLKNPKVKVIFVNIFGGITLASEVAQGIVDALSESNVKKPIVARIVGTAEEEGKKILKEAGIPLFESMDEAAQEAVKLAKAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: TDRD9_DANRE
Sequence: MHQAITSAQIAHWFTVGAQFANIRITNEAKKAEAEDNATEVRSDKAFSELSSPEKEKSDDGNQRRKRAQLPTGPGTSPPSLASYEYPILPITKNRQELVSLIENNSVVIIRGATGSGKTTQLPQFILDHYAERNIPCNLVVTQPRKIGATSIARWVARERKCTLGSLVGYQVGLEKMATEHTKLIYVTTGVLLQKLVSSKTLTEYSHIFIDEVHERSEELDFLLLVVRKLLRSNSRYVKVILMSATINCIEFAEYFGSPIRNQMNPAYVFEVEGAPYAVEEYYLDELKTMLPVGVNLDLTLPQDPYITEEMYNVAVSLIQSFDEMEAKDHRRSEQTGSTTHPERGSVLVFLPGLAEIQYMKEALSKLVRKRLQVYPLHSTVTLEEQNGVFLVPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLVRQLACDKETNYRCLRITWASKTSCNQRRGRAGRVSKGFCYRLVTRHFWENEIPNFSIPEMLRSPLASTLLKVKLLDMGDPRSVLSTALTPPILGDIERTVLQLKQIGALSVQSNSQRQFDGDLTFLGRVLAQLPVDLQLGKLIVLGHVFGCLEECLIIAASLSLKSFFAMPSLQQLAGYRSKLSFAQNVPSDFIAYVNAFKAWYTSRAKGELRHPKDELEWGKENCIQIKRIREVAELFEDLKKRVSRFNMHISSSSNPTDYTSLHKQRFILQVVIAGALFPNYFSQGEIDEQLASKELSGNDPKTTILIRNLPPFAFLCYKQLQSLFRQCGQVKSIAFDGSRAYVEFHRSCVRESGVLHEVLLALLRSRHTPALHLQVHHADEVEFHAKGKPIAHLRYTRVNVDVQSHTVSPVGVLSSSVNPEKLPTSRDFVINITEVIDVGHFWGFQTDENSVEKQCQLTAALNMRDLRPLSVSLYPNLLCVAPFKDGQQMAKYYRAKVLHILGSNVEVFFVDFGNTTVVPSSSLRELPSDLMTPAFQAQEFCIARMAPSAQSLILGDRWSSRARNRFKTLTSGRSAIVSLFSILHGVMRVDLHISTETGDVSVADLLVQEGHACHTPESFESQQSHEVLISLYEDMASGRFTPSFASGSLNSRMEEDKQLINQLLLHFCSSGSSAPKCKAVVHGPSSPHKVNFHSMSKVSNFRSVNIERDSINCVMVNENPQDWHERMLVAASVSLSASGSRILLKETSLMPHIHGLPSLVTMLFTPVMELRTNEDRTCFTGALCGLGWNSVSQEAVLPEHDIEIAFDVKFEIEDITEINALRGTVNRLVCDGPNGLLNLSQEKISSLQEEARERLIRLFIKTPSRPECTPVYHDKFKKWNLVDRSQQMEIQEKDDGKSKGVLFQLHPITLLNM
What is the function of this protein?
ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Acts downstream of piRNA biogenesis: exclusively required for transposon silencing in the nucleus, suggesting that it acts as a nuclear effector in the nucleus together with piwil4.
What are the official names of this protein?
ATP-dependent RNA helicase TDRD9, Tudor domain-containing protein 9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to piP- bodies, a subset of the nuage which contains secondary piRNAs. PIWIL2 is required for its localization to piP-bodies.
Protein: R126B_XENLA
Sequence: MAEALPEAGRYFCHSCTAEITPRLPEYTCPRCDSGFIEELPETSRNSESNSSNNSGTDQNRPSFENIESAQFTLPSGYGQVTFGIFNEGLDFPMFGTSGPVEETRDGESRREHQSRQRYGARQPRARMSTRRGAGRNEGVPTLEGIIQQLVNGIIAPTAMSNLGVGPWGVLHSNPMDYAWGANGLDTIITQLLNQFENTGPPPADTDKIQALPTIQITEEHVGFGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQNTATNPPGLTDMTFSSSSTSSSSSTSPTDENNTANNS
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins.  Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates.  Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome.  Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targeting to the proteasome.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF126-B, RING finger protein 126-B, RING-type E3 ubiquitin transferase RNF126-B.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GFA_PYRTR
Sequence: MPSIHPSIDNGITKGNPNFKGGKLYCHCPTRKVEVTLASNVAHNHACGCSKCWKPKGALFSVVGVVPKDAVSVTANGDKLHIIDESAAIQRNACKECGVHLFGRIVVDHPFKGLDFVHTELSPQKGWQEPQFAAFVSSIIEQGFKPSEMDAVREKFRKVGLQPYDVLSPALMDLIATYTAQKSGKLPSKL
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Putative glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: MUTS_BURM7
Sequence: MATQIDASSEAAAATAAAQHTPMMQQYLRIKSEHPDTLVFYRMGDFYELFFEDAEKAARLLDLTLTQRGASAGTPIKMAGVPHHAVEQYLAKLVKFGESAAICEQIGDPATSKGPVERKVVRVVTPGTLTDAALLSDKSDVFLLALCVGHNKRGVASNIGLAWLNLASGALRLAELAPDQLGAALERIRPAEILAADGTIESVPAGMGAITRVPAWHFDIASGTQRLCDQLEVASLDGFGAQALTSANGAAGALLIYAAATQGQQLRHVRSLKVENESEYIGLDPSTRRNLELTETLRGTESPTLYSLLDTCCTAMGSRLLRHWLHHPPRASVAAQARHQAIGALLDAPPNAGLDSLRSALRQIADVERITGRLALLSARPRDLSSLRDTFAALPALRERVAEIASNAAALGRLEAALEPPPGCLDLLTRAIAAEPAAMVRDGGVIARGYDAELDELRDISENCGQFLIDLETRERARTGISNLRVEYNKVHGFYIEVTRGQTDKVPDDYRRRQTLKNAERYITPELKTFEDKALSAQERALARERALYDGVLQALLPHIEGCQRVASGLAELDLLAAFAERARTLDWVAPEFTDEIGIEIDQGRHPVVEAQVEQFIANDCALNPERKLLLITGPNMGGKSTFMRQTALIALMAYVGSYVPAKAARFGPIDRIFTRIGAADDLAGGRSTFMVEMTEAAAILNDATPHSLVLMDEIGRGTSTFDGLALAWAIARHLLSHNRCYTLFATHYFELTQLPAEFPQAANVHLSAVEHGHGIVFLHAVEEGPANQSYGLQVAQLAGVPAPVIRAARKHLAHLEQQSAAQATPQLDLFAAPPVVDEPECNEPPAAATPHPALERLLELDPDDLKPRDALDLLYELHTLARSGPADAQR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: IRAM_ECOLI
Sequence: MKWIVIDTVIQPTCGISFSAIWGNMKMIIWYQSTIFLPPGSIFTPVKSGIILKDKEYPITIYHIAPFNKDLWSLLKSSQECPPGESKITNKCLHNSCIIKICPYGLK
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation.  May also be involved in the early steps of isoprenoid biosynthesis, possibly through its role as RssB regulator.
What are the official names of this protein?
Anti-adapter protein IraM, Enhancing lycopene biosynthesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the IraM/RssC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_THET8
Sequence: MLRRALEEAIAQALKEMGVPVRLKVARAPKDKPGDYGVPLFALAKELRKPPQAIAQELKDRLPLPEFVEEAVPVGGYLNFRLRTEALLREALRPKAPFPRRPGVVLVEHTSVNPNKELHVGHLRNIALGDAIARILAYAGREVLVLNYIDDTGRQAAETLFALRHYGLTWDGKEKYDHFAGRAYVRLHQDPEYERLQPAIEEVLHALERGELREEVNRILLAQMATMHALNARYDLLVWESDIVRAGLLQKALALLEQSPHVFRPREGKYAGALVMDASPVIPGLEDPFFVLLRSNGTATYYAKDIAFQFWKMGILEGLRFRPYENPYYPGLRTSAPEGEAYTPKAEETINVVDVRQSHPQALVRAALALAGYPALAEKAHHLAYETVLLEGRQMSGRKGLAVSVDEVLEEATRRARAIVEEKNPDHPDKEEAARMVALGAIRFSMVKTEPKKQIDFRYQEALSFEGDTGPYVQYAHARAHSILRKAGEWGAPDLSQATPYERALALDLLDFEEAVLEAAEERTPHVLAQYLLDLAASWNAYYNARENGQPATPVLTAPEGLRELRLSLVQSLQRTLATGLDLLGIPAPEVM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUC10_CAEEL
Sequence: MKLHEENNKALFEAMRNRENPTKWESYKQVITAVSAYWVFSIGLVFLNKYLLSSVQLDAPLFITWYQCLVTVFLCLFLSKTSKAYGLFKFPSMPIDAKISREVLPLSVVFVAMISFNNLCLKYVGVSFYYVGRSLTTVFNVVCTYLILGQKTSGQAIGCCALIIFGFLLGVDQEGVTGTLSYTGVIFGVLASLSVALNAIYTRKVLSSVGDCLWRLTMYNNLNALVLFLPLMLFNGEFGAVFYFDKLFDTTFWILMTLGGVFGFMMGYVTGWQIQATSPLTHNISGTAKAAAQTVMAVVWYSELKTLLWWTSNFVVLFGSGMYTYVQKRVMDKKNSGASPASEAKSDKVKLLGRDGNAAEESV
What is the function of this protein?
Involved in GDP-fucose import from the cytoplasm into the Golgi lumen.
What are the official names of this protein?
GDP-fucose transporter, Nucleotide sugar transporter protein 10.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35C subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CAPSD_LOLV
Sequence: MSESKAETPSKSAEKGVASLSTSAPPSSTTPTAQAKQTPPPVATTARPMASRLPRTIAAEGGGTEKKQSHLAEDRIAQYLPKQDAVDHSNLAALLQPFTEASYEREFDVKVNGIASKAELTAVAETWASRLNVPKENSAVLAQEIAIHCYHNGSSEQTDFNLKSSQVAGLNLEAAVGVIKEILTLRQFAAYYATFVWNWGIKNEIPPANWVAKGYTDETKYAAFDTFSYVGSPLGLRITPTRKPTNNEYMAASVNAREKIIQSRGKGMVTNSPMFSDGTTHQGIPLHPKLPLS
What is the function of this protein?
Required for genome encapsidation.  Forms ribonucleoprotein complexes along with TGB1 helicase and viral RNA (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the potexvirus capsid protein family.
What are the subcellular locations of this protein?
Virion. Host chloroplast envelope.
Protein: DUT_VZVD
Sequence: MNEAVIDPILETAVNTGDMFCSQTIPNRCLKDTILIEVQPECADTLQCVLDDKVSRHQPLLLRNHKKLELPSEKSVTRGGFYMQQLELLVKSAPPNEYALLLIQCKDTALADEDNFFVANGVIDAGYRGVISALLYYRPGVTVILPGHLTIYLFPVKLRQSRLLPKNVLKHLDPIFKSIQVQPLSNSPSNYEKPVIPEFADISTVQQGQPLHRDSAEYHIDVPLTYKHIINPKRQEDAGYDICVPYNLYLKRNEFIKIVLPIIRDWDLQHPSINAYIFGRSSKSRSGIIVCPTAWPAGEHCKFYVYNLTGDDIRIKTGDRLAQVLLIDHNTQIHLKHNVLSNIAFPYAIRGKCGIPGVQWYFTKTLDLIATPSERGTRGFGSTDKETNDVDFLLKH
What is the function of this protein?
Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RS3_HYDS0
Sequence: MGQKTHPIGFRIGVTKDWLSKWCTSKKEYPNTLHEDIVIRKYIKERYKSAGISKVTIERSGEKIRVRILSSKPGIIIGRKGAEVDQLKNDLERIVKNKDISLSVDEVRVPQLDAQLVAEDIALQIERRVSHRRAMKRAIDNAIKSGAKGIKVQVKGRIGGADLARAEWFLVGRMPLQTLRADIDYGYATAYTKYGILGIKVWIYKGDILKGGKEEIMKKIEEDLVSQAKEV
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL35_DESAL
Sequence: MPKIKTNRAAAKRFKKTGSGKVKYSKSFGSHILAKKSRKRKRDLRQSHILDEANMKNIKRLLPYW
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: YTM1_CRYNB
Sequence: MSIDPAGSQASRQLPINLFTRSPTDAIPQSTYFIPSAWRRFQLSELINQVLGNTAENGSKPVPFDFLVNGEVLRGSLEAWVKKNRGGDEESQIDVEYVRSVMPPEEAARVEVEDWVSGLSLSRKGYVLLSSYLSHLQVLPLSAAAQSSSALYTLPLPTSLGATSCTWVSPQTQETDILVAAGGVDRQTHVYSIPSLSPDTADAPRELYTLHGHTGPISSVIASSSGKEIVTGSWDGNINLYVLPDAEPTEHQVPADPVSYLPGQGTKKRRKLEKDQEKAPIEGLTDGDATGEGGWRRAPDAVMRGHTGRVGGLVWDKLDSGKIWSAGWDGSVRGWEVETGAAGALRQGPFDKSALCVDQWKMNGTLATGNMDRTICLWDTRQATSLISLTLPTTSPVPSVTCHPTSPFTLASATYSGVVQIWDIRSPKTALFTVSKAQSKLADPNRKVTKNGKVLGERLLAVDWNGEVLVAGGEDGEVGIWRARGE
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein YTM1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: MDHP_MAIZE
Sequence: MGLSTVYSPAGPRLVPAPLGRCRSAQPRRPRRAPLATVRCSVDATKQAQDGVATAVATEAPASRKECFGVFCTTYDLKAEDKTKSWRKLVNVAVSGAAGMISNHLLFKLASGEVFGQDQPIALKLLGSERSFQALEGVAMELEDSLYPLLREVSIGIDPYVVFQDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASRNDEVLVVGNPCNTNALICLKNAPNIPAKNFHALTRLDENRAKCQLALKAGVFYDKVSNVTIWGNHSTTQVPDFLNAKIDGRPVKEVIKDTKWLEEEFTLTVQKRGGVLIQKWGRSSAASTAVSIVDAIRSLVTPTPEGDWFSTGVYTTGNPYGIAEDIVFSMPCRSKGDGDYELASDVLMDDFLWERIKKSEAELLAEKKCVAHLTGEGNAFCDLPEDTMLPGEV
What is the function of this protein?
The chloroplastic, NADP-dependent form is essential for the photosynthesis C4 cycle, which allows plants to circumvent the problem of photorespiration.  In C4 plants, NADP-MDH activity acts to convert oxaloacetate to malate in chloroplasts of mesophyll cells for transport to the bundle sheath cells.
What are the official names of this protein?
Malate dehydrogenase [NADP], chloroplastic, NADP-MDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IF2_YERPS
Sequence: MTDVTVKSLAAEIQTPVDRLVQQFADAGIKKSDVDSVTQQEKEILLAHLNREHGSVPNKLTLQRKTRSTLNIPSTGGKSKSVQIEVRKKRTYVNTPEAEQAKAEEQAQREAEEQAQREAEATAQKIAEEKAKREAEEQAKREAAEKAKRQAAEKEKVTNQQTDEKTKPAQTDKARREAEAAELKRSVEEETRRKVEEDAKRVAEEARKMAAENEGKWPEPVAEQTESADYHVTTSQHARAAEDENDAKVEGDRRSRTRGGKATKQKKGNKLSESKADREEARAVGRKGKRKPSTLQQSFNKPVVAVNRDVVIGETVTVAELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEALMSDRDIGVEAAAEHRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAANVPVVVAVNKIDKPEADPDRVKTELSQYGIQPEEWGGESQFINVSAKAGIGIDELLNAILLQAEVLELKAVRTGMANGVVIESFLDKGRGPVATVLVQQGTLNKGDIVLCGFEYGRVRAMRDELGRDITSAGPSIPVEILGLSSVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVSELNIVIKSDVQGSCEAICDSLEKLSTDEVKVRIVGSGVGGITETDATLAAASGAIILGFNVRADASARRVVETEGLDLRYYSVIYSLIDEVKQAMSGMLAPEYKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVIKRNNPIRVLRDNVVIYEGELESLRRFKDDVSEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIKRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY2_BORAP
Sequence: MKIALSGKSGCGNTTVSSMIAKHYGLEFINYTFHDIARERNIPFSEFYEKEIIGRDDYYWDRYLDKRLFALSKKNNTVLASRLAIWISKSADLKIYLYAKMEVRAERIMTREGGMYSDVLSSTFNRDENDKKRYLAIYNIDIDDYSSETDLVIDVTNINSNEVFELIRDEIDKRNLKN
What are the official names of this protein?
Cytidylate kinase 2, CK 2, Cytidine monophosphate kinase 2, CMP kinase 2.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_METRJ
Sequence: MAATKSEPLDLDLTAEEARAEYARLSDAILEADRLYYQEDAPEISDAEYDRLRRRLEDIEARFPDLAGTGAASTSVGAKPSEKFAKVRHAVPMLSLGNAFDDAEVAEFVARVRRFLGWSDDTPLAFTAEPKIDGLSLSLRYVNGRLDTAATRGDGEVGENVTANARTVQDIPAVLAGAGWPEICEVRGEVYLSHADFAAINARQEAAGKPLFANPRNAAAGSLRQLDPAITASRPLRFFAYAWGELSAPIAETQTGVLEQFATWGLPVNPRTETFTDTAAMLAHYRRIEADRAGLGYDIDGVVYKVDDLALQKRLGFVSRSPRWALAHKFAAQEATTVVEDIVINVGRTGSLNPLAKLRPVTVGGVVVSNATLHNEGYVKGVGADGEPIRDGRDIRVGDTVTVVRAGDVIPKVMDVDLTKRPADSRPYAFPESCPACGSRAVRAINPRTGRPDAVRRCTGGLICPAQGVERMKHFVSRNGFDIEGFGETYIEVLFEAGLVRQPADLFRLDFEELKAAIVARREALSAERRAESGTAEPPKKAAKKKGDEDDKAIKNLLAAVEARRAVPMNRLLFALGIPQIGEATAKALAKRFADMPTLIAAIREAAAAQPGPDWVELTAVPRVGGTTRDRLLDLGFPEDDAAPAKERARLSAVQRENLLAHYGDVDAVRAAIAQAAAQRPGDAYRVFADDGEIGPVATDALLLFFSEPHNADAVTALLDAVAVQPMERAAAASTFAGKTVVFTGALEKMTRNEAKAVAERLGAKVSGSVSAKTDLVVAGPGAGSKLKDAQKHGVRVVSEDDWLAMVAQG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PRXD1_XENLA
Sequence: MAGDLRQELLAYLHELDIRPVCAEHPEVFTVEEMMPHVQHLGGAHSKNLFLKDKKKKGLWLVSVLHDRQVNLNDLAKKLNLGSGNLRFADEASMLEKLKVGQGCATPLALFCDRGDVQFVLDAQFLEGGYERVYFHPMTNAATLGMTPQEFVTFLKKTGHDPIIIHFD
What are the official names of this protein?
Prolyl-tRNA synthetase associated domain-containing protein 1, PrdX deacylase domain-containing protein 1, Prolyl-tRNA synthetase associated domain-containing protein 1 pseudogene.
What is the protein family that this protein belongs to?
Belongs to the PRORSD1 family.
Protein: FOXL2_PIG
Sequence: MMASYPEPEDAAGALLAPETGRTAKEPEAPPPLSPGKGGGGGASTAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGAGGAAGGCGVAGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYSRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHSHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTNAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL
What is the function of this protein?
Transcriptional regulator.  Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination (By similarity).  Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity).  Has apoptotic activity in ovarian cells (By similarity).  Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity).  Activates SIRT1 transcription under cellular stress conditions (By similarity).  Activates transcription of OSR2 (By similarity).  Is a regulator of CYP19 expression (By similarity).  Is a transcriptional repressor of STAR (By similarity).  Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity).
What are the official names of this protein?
Forkhead box protein L2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRR_BACC2
Sequence: MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEMEVGELDITLYRDDLTLQSKNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEERIEVDLQETDQQDRVSIYDK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: RL11_PARXL
Sequence: MAKKIIGFIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAQTQALEPGLPIPVVITAFADKSFTFVLKTPPATVLIKKAAKIDKGSSKPHTDKVGKITRAQAEDIAKTKMPDLTAADLDAAVRTIAGSARSMGITVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: YCJF_ECOL6
Sequence: MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDEAQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQQAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRRQLIGQVKETLQKGKTPSEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBEY_BUCCC
Sequence: MNIKKNLMKIDIQNVCKKNIFFPKKKYFFLWLKNIFKNKKIEITIRIVDMLEMKFLNKKYKKKNSLTNVLSFQSPDSIKIKHRFLNYIGDIILCAPYINKEANILKKKKIELWAHMTIHSTLHLLHYSHKDSKSKKNMQKTEIYIMKKLGYNNPYN
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPIIB_ARTOC
Sequence: MQVLVALAALSSLAAPVVGFSIPRGVPVSQSMIDVKLSSAGNSMVKATITNNGDRALNLLKFHTIMDSNPTRKVSIESQDGKEVQFTGMMPRYKNTDLKPTYFMSLPPKGTVEHSFDIAATHDLSRGGQFTLKAEGMVPIAEENSTNITGAAQYHSNELHMTIDGDQAASVKSAIGVAKRDGPFTRIDKRTKIDMQSCGNRQELQALTAALSASAKLSSMSAQAVGQNQQKYMEYFKDPKYAKTVQSRFQAVAKESSSTNNGGTTYFCSDVMGGCEEGVLAYTLPSRNQVYNCPIYYSELPPLTKECHAQDQATTTLHELTHNPAVQEPFCEDNGYGYERATALSAEKAVQNADSYALFANAVYVGC
What is the function of this protein?
Probable secreted metalloprotease that shows high activities on basic nuclear substrates such as histone and protamine (By similarity).  May be involved in virulence.
What are the official names of this protein?
Probable neutral protease 2 homolog MCYG_00239, Deuterolysin MCYG_00239.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERPA_JANMA
Sequence: MNAVAEMPSPIVFSDSAAMKVAELIEEEGNPDLKLRVFVQGGGCSGFQYGFTFDEIVNEDDTTMTKNGVQLLIDSMSYQYLVGAEIDYKDDLEGAQFVIKNPNATTTCGCGSSFSA
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: GREA_ROSS1
Sequence: MSDKPAYLTRDGRARLEAELEELVTKGRKEIAERINAAKELGDISESGEYEDAKNQQAHLEGRIREIKSILARAQIIDEENGDNHEVRIGSRVTVRIDGEDGEETWTIVGSTEAKPSEGKISNESPIGSALLGKRPRQKVTVETPSGTMKLTIVDIQ
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.