PharMolix/UniProtQA huggingface dataset:
Protein: HIS1_ECO7I
Sequence: MTDNSRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYD_SYNE7
Sequence: MTNTVPSVPAVPNLPTQSDPFFNERSLEQLTQTVLQDLQQAGVSEAESAPTPLSVPTPALPTTSALAVPQSPTAIANVPAPPSSIDERSLAQLAQAVLQDPQLASAIASIFPSVTLPTSASVPRSVPVPPSFLPSLVPTAPPIHDEVGVIPHHQLPVPSQPTPAGLQQTASSKSGSGFYFIDEQVETAIAALHSNLTVFPQLTTSSIPTLTGAHSAGAVGFDIHQVRRDFPILQERVNGRPLVWFDNAATTQKPQVVIDRLSHYYQHENSNIHRAAHELAARSTDAYEAAREQVRHFLNAASTEEVVFVRGTTEAINLVAKSWGSQNLKEGDEIVITWLEHHANIVPWQQLSAETGARLRVVPVDDYGQVRLDEYQKLLSDRTKIVSFTQVSNALGTITPAKEIIELAHRYGAKVLLDGAQSVSHLAVDVQALDCDWFVFSGHKVFGPTGIGVLYGKQELLDATLPWQSGGNMIADVTFEKTVYQPAPARFEAGTGNIADAVGLGAALEYVQKIGLEAIAAYEHELLVHGTALLSQIPGLRLIGTAPHKAAVLSFVLEGFSPEAIGQALNREGIAVRAGHHCAQPILRRFGLETTVRPSLAFYNTFEELETLAAAIRRIQTGSLAL
What is the function of this protein?
Cargo protein of a type 2A encapsulin nanocompartment probably involved in sulfur metabolism.  Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.
What are the official names of this protein?
Cysteine desulfurase, CyD.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Encapsulin nanocompartment.
Protein: HIS5_ALIF1
Sequence: MTNQNVVIIDTGCSNVSSVRFAIERLGYEVTISRDPQVVLAADKLFLPGVGTASEAMKNLAERDLIELVKQVEKPLLGICLGMQLLGKLSEEKGQKADQIVDCLGLCDGEVRKLQTGDLPLPHMGWNTIKPVEGNPLFKDIPENSYFYFVHSFGMQVGDYTIASCDYGQPFTAALQAGNYYGVQFHPERSSKVGSKLIQNFLEL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR26_HUMAN
Sequence: MQANGAGGGGGGGGGGGGGGGGGGGQGQTPELACLSAQNGESSPSSSSSAGDLAHANGLLPSAPSAASNNSNSLNVNNGVPGGAAAASSATVAAASATTAASSSLATPELGSSLKKKKRLSQSDEDVIRLIGQHLNGLGLNQTVDLLMQESGCRLEHPSATKFRNHVMEGDWDKAENDLNELKPLVHSPHAIVVRGALEISQTLLGIIVRMKFLLLQQKYLEYLEDGKVLEALQVLRCELTPLKYNTERIHVLSGYLMCSHAEDLRAKAEWEGKGTASRSKLLDKLQTYLPPSVMLPPRRLQTLLRQAVELQRDRCLYHNTKLDNNLDSVSLLIDHVCSRRQFPCYTQQILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDLDGNLLDSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTDRNIVQEDHPIMSFTISKNGRLALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWGPAPFIDHQNIEEECSSMDS
What is the function of this protein?
G-beta-like protein involved in cell signal transduction (PubMed:15378603, PubMed:19446606, PubMed:22065575, PubMed:23625927, PubMed:27098453, PubMed:26895380).  Acts as a negative regulator in MAPK signaling pathway (PubMed:15378603).  Functions as a scaffolding protein to promote G beta:gamma-mediated PLCB2 plasma membrane translocation and subsequent activation in leukocytes (PubMed:22065575, PubMed:23625927).  Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (PubMed:29911972).  Acts as a negative regulator of the canonical Wnt signaling pathway through preventing ubiquitination of beta-catenin CTNNB1 by the beta-catenin destruction complex, thus negatively regulating CTNNB1 degradation (PubMed:27098453).  Serves as a scaffold to coordinate PI3K/AKT pathway-driven cell growth and migration (PubMed:26895380).  Protects cells from oxidative stress-induced apoptosis via the down-regulation of AP-1 transcriptional activity as well as by inhibiting cytochrome c release from mitochondria (PubMed:19446606).  Protects also cells by promoting hypoxia-mediated autophagy and mitophagy (By similarity).
What are the official names of this protein?
WD repeat-containing protein 26, CUL4- and DDB1-associated WDR protein 2, Myocardial ischemic preconditioning up-regulated protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: RS20_METRJ
Sequence: MANTASAKKMTRKIAKRTAINRSRRSRMRTFVRKVEEAIASGNQQDALAALRAAEPEMMRAAQHGIVHKNNASRKVSRLAARVKALAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: ARTQ_HAEIN
Sequence: MFSDFLSLMFTAALMTLGLAVCSLLLGLFLSLIFAVLEANRFVGKPMTVFVALLRGLPEIIVVLLVYFGSTELVEMLTGEYIEFGAFGCGVLALSLIFAAYASQTLRGAIQAIPKGQWESGAALGLSKSYTFIHIVMPQVWRHALPGLSTQWLVLLKDTALVSLIGVDDLMHQADLINTNTHQPFTWYGIAALIYLAVTLISQVGIRKLELRFTRFERGVK
What is the function of this protein?
Part of the ABC transporter complex ArtPIQM involved in arginine transport.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Arginine ABC transporter permease protein ArtQ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SOPE_SALHA
Sequence: MTKITLFPHNFRIQKQETTPLKEKSTEKNSLAKSILAVKNHFIKLNSKLSERFISHKNTESSATHFHRGSASEGRAVLTNKVVKNFMLQTLHDIDIRGSASKDPAYASQTREAILSAVYSKYKDQYCNLLISKGIDIAPFLKEIGEAAQNAGLPGATKNDVFTPSGAGANPFITPLITSAYSKYPHMFTSQHQKASFNIYAEKIIMTEVVPLFNECAMPTPQQFQQILENIANKYIQNAP
What is the function of this protein?
Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF).  This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells (By similarity).
What are the official names of this protein?
Guanine nucleotide exchange factor SopE, Effector protein SopE, Toxin SopE.
What is the protein family that this protein belongs to?
Belongs to the GEF (guanine exchange factor) SopE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS).
Protein: MIAB_CAMHC
Sequence: MKLLYLQTLGCAMNVRDSEHIVAELKDEYKLTDDISKADLILINTCSVREKPVHKLFSEIGAFNKVRKNGSKIGVCGCTASHLGEEIFNKAPFVDFVLGARNVSKISEAVKTPKFISTDINYDESEFAFGEFRGSPYKAFVNIMIGCDKKCSYCIVPQTRGKEISIPAEIILNEASKAVQNGAKEIFLLGQNVNNYGKFFSSRHEKMDFSDLLVKISEIKGVERIRFTSPHPLHMDDKFLDIFTSNPKICKSMHMPLQSGSTKVLRDMRRGYDKEWFLNRALRLRKMCPEVSISTDIIVAYPTESEDDFKDTMEVLNEVKFEQIFSFKFSPRPLTAAENLPLIDNEIASKRLEILQSRHNEILDEIMKNQVGKIFDVYFEELRANGEVAGRSFSNFLVSVKGSEDLLGKILPVRIEKASRMVLYGKITA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGR_METTP
Sequence: MRCDVVVVGAGPGGSMAAKTAAEKGLKVVLVEKRQEIGDPVRCAEGVSKARLSSMIKPDPKWIASEVKGARLYAPDGSNVVMSEDKSGDEVGYVLERKIFDRALAMDAARAGARVMVKTRALDLLRANGSVKGIRAMRYGEIIDIEADVVIGADGVESKVGRWAGIDTALKPGDIEVCAQFLLYDKGIDDEYCEFFLGNELAPGGYVWSFPKGEHLANVGLGVIGSRSEPGAPVKLLRRFVERRMPEARIVEMVVGGVPVSGPIERTIADGVMLVGDAARQSDPITGGGILNAMQAGMIAGEVVADAVSSGDTGVEGLMAYEKRWRESIGKQIARHLDLKEFFIRLSDDDLNKLMHSIQSEDVSKMDLRGMLRVLIRLNPKMLWELRHLVM
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
Protein: APOE_PLEMO
Sequence: MKVLWAALLVAFLAGCQGKVEQVVEPELEPEPELHQQADWQSGQPWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELTALMDETMKELKAYKSELEEQLSPVAEETRARLSKELQAAQARLGADMEDVRSRLAQYRSEVQAMLGQSTEELRARLASHLRKLRKRLLRDVDDLQKRLAVYQAGAREGAERGVSAIRERLGPLVEQGRARAATVGSSLAGQPLQERAQAWGERLRARMEEVGSRTRDRLDEVKEQVEEVRAKLEEQAQQMRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGASAAPVPSDNH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: ALIB_STRR6
Sequence: MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPSSLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAKWFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGVKALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFLMKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFPNSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNKNFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYGKEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGVSSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPSTYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYADIQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDEYAKAREKWLKEKEESNKKAQEELAKHVK
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides; probably an oligopeptide binding protein.
What are the official names of this protein?
Oligopeptide-binding protein AliB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PTH_MACCJ
Sequence: MKCIVGLGNIGKKYELTRHNIGFMVVDRLVESYNLELNQQKFKGLYAIAMINGEKVLLIEPMTYMNSSGEAVRPLMDYFNVSTEDLLVLYDDLDMPPGRLRLRQKGSAGGHNGIRSLIQHLGTDQFKRIRIGIGRPTGHLKVVDFVLQKFTPDEMIVMDKVINQTIKAVEAFIAGERFENIMNQYNGDV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_PSEPK
Sequence: MRSKVTGAKRWVVKIGSALLTADGKGLDRGAMAVWVEQMVALREAGVELVLVSSGAVAAGMSQLGWTKRPSAMNELQAAASLGQMRLVQAWESSFGEHGKHTAQILLTHDDLSDRKRYLNARSTLRTLVDLGVVPVINENDTVVTDEIRFGDNDTLAALVANLVEADLLVILTDRDGMFDADPRNNPEAQLIYEARADDPSLDAVAGGTGGALGRGGMQTKLRAARLAARSGAHTIIIGGRIERVLDRLKAGERLGTLLSPERGMLAARKQWLAGHLQTRGTLVLDAGAVQALRQANKSLLPVGVKTVQGSFRRGEMVVCVGPDGVEVARGLANYSALEAQKIIGQSSEAIESILGYSAEPELVHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTURN_DANRE
Sequence: MEFKELVDAAEKWCTGNPFDLIFAEDVDERRLDFYAEPGISFYVLCPDNLTGGTDNFHVWSESEDCLPFLQLAQDYISSCGKKTLLEVLDKVFRSFRPLLGLPDIDDDTFDQYHADVEEEPEPDHQQMGVSQQ
What is the function of this protein?
May be involved in early neuronal development (By similarity).  May play a role in promoting megakaryocyte differentiation (By similarity).
What are the official names of this protein?
Maturin, Maturin neural progenitor differentiation regulator protein homolog.
What is the protein family that this protein belongs to?
Belongs to the MTURN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARFK_ORYSJ
Sequence: MASSQEKAKTGVLRNAAALLDEMQLMGETQGAKKVINSELWHACAGPLVCLPQRGSLVYYFPQGHSEQVAATTRKIPNSRIPNYPNLPSQLLCQVHNITLHADKDTDEVYAQMTLQPVNSETDVFPIPTLGAYTKSKHPTEYFCKNLTASDTSTHGGFSVPRRAAEKLFPQLDYSMQPPNQELIVRDLHDNMWTFRHIYRGQPKRHLLTTGWSLFVGAKRLKAGDSVLFIRDEKSQLLLGVRRATRQQTMLSSSVLSTDSMHIGVLAAAAHAASSGSSFTIYYNPRTSPSPFVIPVARYNKATYMQPSVGMRFAMMFETEESSKRRYTGTVVGISDYDPMRWPNSKWRNLQVEWDEHGYGERPERVSIWDIETPENTLVFPSSTLNSKRQCLPGYGVSVPGMEIGSANMSSFPRAQGNPYGSLQHIPAVGSELAIMLLNQSGQTLGSPLSFHQSSYSSIIQNVKQNYIPPLTVSTSACLTKQESLPSDDAQHQFHMANMQNGDLEGSEVQPVIDSISESKLNATSRDPRNTDSYTSRSTSEQNSKGEPRGKTRRSKKGLPHKTVSEKSDLSSAPSWICDNQQVGLESKLVGCDEQVNCGNIEDSSGALTQGNFVGQPHGHQVEQKGVLSPPKVESSKSPDGGKSVNSFPNQGCFSQFIDGLDWMTQPSYYQDSNVIQPAGVSENIFSSSADIPPSMIADTMETFQASCLSDCLPNSIQEFISSPDLNSLTFLSPDMQNLEVQLQHDGSNLPSTSNSFVQMSFSEESASQSANLSGLHMESTHRSINTTSCSQPMSTGGFDAGMYSKLPRLKESQILSLPEIHTNSMGTSACSMDATEYSLDRSAKPMKPPVRTYTKVQKQGSVGRSIDVTGFRNYHELRSAIACMFGLQGKLEHPGSSEWKLVYVDYENDVLLVGDDPWEEFINCVRCIRILSPSEVQQMSENGMHVLNDCIQAA
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
What are the official names of this protein?
Auxin response factor 11, OsARF5, OsMP, Protein MONOPTEROS-like.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS9_YERPN
Sequence: MAENQYYGTGRRKSSSARVFLKPGSGKIVINQRSLEVYFGRETARMVVNQPLELVDMVTKFDMYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAGFVTRDAREVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: SYFA_PROMH
Sequence: MPHLAELVAQAKAAIEEAQDVAALDSVRVEYLGKKGHLTLQMSTLRDLPAEERPAAGAVINQAKQEVQQALNARKEQMESALLNERLAAEKIDVSLPGRRIENGGLHPVTRTIERIETFFGELGFSVESGPEIEDDYHNFDALNIPAHHPARADHDTFWFDAKRLLRTQTSGVQIRTMQNKQPPIRIIAPGRVYRNDYDQTHTPMFHQVEGLIVDKDISFTNLKGTLHDFLKNFFEEDMEIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABHD1_HUMAN
Sequence: MLSSFLSPQNGTWADTFSLLLALAVALYLGYYWACVLQRPRLVAGPQFLAFLEPHCSITTETFYPTLWCFEGRLQSIFQVLLQSQPLVLYQSDILQTPDGGQLLLDWAKQPDSSQDPDPTTQPIVLLLPGITGSSQDTYVLHLVNQALRDGYQAVVFNNRGCRGEELRTHRAFCASNTEDLETVVNHIKHRYPQAPLLAVGISFGGILVLNHLAQARQAAGLVAALTLSACWDSFETTRSLETPLNSLLFNQPLTAGLCQLVERNRKVIEKVVDIDFVLQARTIRQFDERYTSVAFGYQDCVTYYKAASPRTKIDAIRIPVLYLSAADDPFSPVCALPIQAAQHSPYVALLITARGGHIGFLEGLLPWQHWYMSRLLHQYAKAIFQDPEGLPDLRALLPSEDRNS
What are the official names of this protein?
Protein ABHD1, Alpha/beta hydrolase domain-containing protein 1, Abhydrolase domain-containing protein 1, Lung alpha/beta hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: EXO5_YEAS1
Sequence: MLGRTLINKHGFLIHPRRFVHLNDKSLDGTFILPSKKNHMYDVPTNDPSGILNASDIDRINNLPFFDNTSPTKETNTKEGALLSEKLASVKELFGEDPENPSFINYRFPRGLENPYFDIQVNQLKKKRLSVTQLCTTQNWCELRNFYDFYSQNLSNQLLNLKFQVQKGKKIHKSLEDETHPELNQYKSFTHNFLALTKLSMDIDNDMDALLDNWFNSINRLVSLFTKGDGHAREIVCHGFINLEDGKLVEHLLNSDSKTKENVIISGVIDHLTLRNKHNHQVQKGAAHLDTEYQSWGNILTNLLSNLKELKSNNEIVISDIKTRSVPKIPSIESVIESSKLQTMYYKFFFSHLSQDMTQTYHSFLINAKRRGLDVDAPINPTKILTFILTNPLFANDVKNLLYGLPINHSAFDNDAKGSNTFDMAAFNDLLDRGPTSFNVPIEQDEDSSESTKCVSLRDYGHFYTKWKTPLTLKYFAARLSQIYFIVGNLVSNDLMIEYYYHNDNFHNIIFPYDTLKLGTHAHDSAMVWFGGRDMHPIEPTQKNFNTYCKFCDYRHVCSWKNKNELKLIDLGKELKKIILESSMK
What is the function of this protein?
Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination.  Releases dinucleotides as main products of catalysis.  Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).
What are the official names of this protein?
Exonuclease V, mitochondrial, Exo V, Defects in morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the EXO5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ROA3_MOUSE
Sequence: MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSRRF
What is the function of this protein?
Plays a role in cytoplasmic trafficking of RNA.  Binds to the cis-acting response element, A2RE.  May be involved in pre-mRNA splicing (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein A3, hnRNP A3.
What are the subcellular locations of this protein?
Nucleus. Note=Component of ribonucleosomes.
Protein: B2MG_SAIBB
Sequence: MARSVVAALLVLLSLSGLEAIQHAPKIQVYSRHPAENGKPNYLNCYVSGFHPSDIEVDLLKNGQKIENVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVSHVTFPTPKTVKWDRNM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEC23_ASPOR
Sequence: MDYEALKDQWSDVEDRDGIRLSWNTFPSSRMEASRLVVPIGAVYTPLKDKPDSPLLQYEPVTCKAPCRAVLNPYANVDVRARIWICPFCLMRNPLPPHYKDITESTIPPELHPLSTTIEYQLARPAPTPPIFVYVVDTCQEEDSLKALKDTLVMSLSLLPANALVGLITYGTMAQVHELGYTECAKSYVFRGSKEYAAKQVQEMLGLLSAGVRPNMPQQPARPPLGPAARFLLPVQQAEFQITNVLEQLQRDPWPVANDKRPLRCTGVALSVAVGLLETSFQNAGGRIMVFTSGPATEGPGHVVGPELKEPMRSHHDIDRDNIKYYKKAVKFYDAMAKRAANNGHIVDVFAGCLDQVGLLEMKNLVNYTGGHMLLTDSFTSSQFKQSFVRIFDKDANDNLLMGFNASLEVLTTKELKVTGLIGHAVSLNKKSSSVGETECGIGNTCAWKMCGIDPSSSYGVYFEIANQGGPAAVQPGPQRGMMQFLTYYQHSSGHYHLRVTTVARNLSGPAGDPTLAQSFDQEAAAVLMARIAVFKAEVDDGPDVLRWVDRMLIRLCSRFADYRKDDPTSFRLEKNFTLYPQFMFHLRRSQFLQFFNNSPDETAFYRHVLNHEDVGDSLVMIQPTLDSYSLEHEGSQPVLLDSASIQPSHILLLDTFFHILIFHGETIAEWRKAGYQDQEGYENLKALLEQPKEDARELISDRFPLPRFIVCDAGGSQARFLLSKLNPSTTHTTGGYGGGVTSQTIFTDDVSLQTFMDHLMKLAVSGTS
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein sec23.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS8E_PYRAE
Sequence: MKLGAYYKGGDLKKPSGGKKRKVRKTKKKALGGGPPQIPKLGENDTRIVERVRGGNLKVRLREAKFANVYIPKERKSVKAKIISIISTPANPDFARRNFIVKGSVIQTEVGKALVTSRPGQDGVINAVLIE
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: RL33_BRUSI
Sequence: MAKATTIKIKLLSTADTGFFYVTKKNSRTMTEKMTKTKYDPIARKHVEFKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.