PharMolix/UniProtQA huggingface dataset:
Protein: WAC_DROME
Sequence: MVMHARKPQRMNDGYFEKHTSHTSYQSSKYSSSKRDYERDRSSNYRDRDLSPGAGGGGGGGSAGGGGGGSGNGGGPLNNGNSYRSQSPDIDSPSSRSHDLRDRSDHRGGGGGNGRGGSGERYSFMQKMRDRDRDVYKKDKYSDKRDRRGNDRDSESSYRTNHDRDRRGGGGSGGGSGKLCSSRENDKRSGSDDRDRDRDRDLRDLRDKRDRGSDRDRDMYKKDKYADKRERSDRGERTARYGDWSEHVSSSGKMYYYNCKTEISQWEKPKEWVDRERNLPRDQHREKDYRDKDRDRDRDDRFSRSTYKHSNSSRDNSRLRWNYDNDGGPPSHRRRLDGRHNDNADMDISGDSTPTSEASYSLSGTPTTHGGGPGGGGPGGGGGSNSDQPMGNALPRLSSHPTANSSASVATGTGATGGLHYGSGTGGGPVTGATMLPTMSGMLNSNSSNSAGGSSSNASSSSLRNSVVGHIGSTSGTTVPTLGSQDPHQHHLNSNAPLPPGAKGKDQALLMRQKMHLGLGVLDVQSHHGVNSVGSVSDGTNHAYNSVNNSVSGSLRDNSVNSPLYMHHSMSPSLNFTKSPIPTIVGHTNNMSIAYTCNPPFGLKATLDGGVMVANASPATPGGNASSGSSGANSSQSIVPGMGPVCGISVITSMGSNSGTLCEGPPTPTQELDLSGSALEQQQLAAAAAAATASSLQLQAAQQAQQQRKLDGTSSATLSSLQSCVSSSGQAANLRGPEISPKLAKYFRADLIAHVTNWHAEVLERQAQKCCEDTHLFGDITCTRICAELKCARSLVRSTEINATLQEQKIMYLRHQIRRIEESKTQNAFMSDDT
What is the function of this protein?
Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-118' (By similarity).  Regulates the cell-cycle checkpoint activation in response to DNA damage (By similarity).  Positive regulator of amino acid starvation-induced autophagy (PubMed:26812014).  Also acts as a negative regulator of basal autophagy (PubMed:26812014).  Positively regulates Tor activity (PubMed:26812014).  Promotes, in an energy-dependent manner, the assembly of the TTT complex and the RUVBL complex composed of pont and rept into the TTT-RUVBL complex (By similarity).  This leads to dimerization of the mTORC1 complex and its subsequent activation (By similarity).  May negatively regulate the ubiquitin proteasome pathway (By similarity).  Required for habituation, a form of non-associative learning (PubMed:26757981).
What are the official names of this protein?
WW domain-containing adapter protein with coiled-coil homolog, Protein wacky.
What are the subcellular locations of this protein?
Nucleus. Lysosome.
Protein: CTHR1_HUMAN
Sequence: MRPQGPAASPQRLRGLLLLLLLQLPAPSSASEIPKGKQKAQLRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQGSPEMNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGWNSVSRIIIEELPK
What is the function of this protein?
May act as a negative regulator of collagen matrix deposition.
What are the official names of this protein?
Collagen triple helix repeat-containing protein 1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MRNC_LISMO
Sequence: MAEVKEYKQLNGLALAYMGDAVYEKFIREYLLAAGKTKPNQLHKTATKFVSAKGQAVALKAMIAEGFLTEEEDRIAKRGRNAKSYTVPKNTDPGTYSMSTSFEAVLGYLYLAGEMERLQEWMEKALEIVEKGVETN
What is the function of this protein?
Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor.  Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.
What are the official names of this protein?
Mini-ribonuclease 3, Mini-3, Mini-RNase 3, Mini-RNase III, Mini-III.
What is the protein family that this protein belongs to?
Belongs to the MrnC RNase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_THEYD
Sequence: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRAY_CLAM3
Sequence: MVALLFAGAFSLAFTLFLTPLFIKLFHRLQWGQFIRDDGPQTHHTKRGTATMGGIVIILASVLGYFVGHLLTWDGIRFDPVTPSGLLVVFMMVGLGFVGFLDDYLKTRKQQSLGLGGWQKIAGQVVVATVFAVLAITLRDPVSGLTPASTAISLFRDLPLDFMALGAVIGTGLFIVWICLIVASASNGVNVADGLDGLAAGASIFSIGSYVIIGFWQFNQSCDSVSSYQNEYRCYEVASPLDLAIIAASIVGALIGFLWWNTSPAQIFMGDTGSLGLGGALAALAILSRTELLLVFIGGLFVIVAGSVVLQRIYFKLTHGKRIFLMSPLHHHFELKGWAEVTVVVRFWIIAGLLVAAGVGTFYLEWITQ
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAAL1_CARHZ
Sequence: MRIKDVLFVKGSSGFYFDDQKAIKSGAVTDGFTYKGKPLTPGFSRVRQGGEAVSIMLFLENGEIAVGDCVAVQYSGVDGRDPVFLADNFIEVLEEEIKPRLVGYNLVRFREAARYFTNLTDKRGKRYHTALRYGLTQALLDAVAKINRTTMAEVIAEEYGLDLTLNPVPLFAQSGDDRYINADKMILKRVDVLPHGLFNHPAKTGEEGKNLTEYALWLKQRIKTLGDHDYLPVFHFDVYGTLGTVFNDNLDRIADYLARLEEKVAPHPLQIEGPVDLGSKERQIEGLKYLQEKLITLGSKVIIVADEWCNNLSDIKEFVDAGAGGMVQIKSPDLGGVNDIIEAVLYAKEKGTGAYLGGSCNETDVSAKITVHVGLATGPAQLLVKPGMGVDEGLTIMRNEMMRTLAILQRNKVTFQKKVG
What is the function of this protein?
Involved in the methylaspartate cycle.  Catalyzes the formation of the alpha,beta-unsaturated bond by the reversible anti elimination of ammonia from L-threo-beta-methylaspartate (L-threo-(2S,3S)-3-methylaspartate) to give mesaconate.  It can also catalyze the amination of fumarate and ethylfumarate, and the deamination of hydroxylamine, hydrazine, methylamine and ethylamine.
What are the official names of this protein?
Methylaspartate ammonia-lyase 1, MAL, 3-methylaspartate ammonia-lyase 1, Beta-methylaspartase 1.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate ammonia-lyase family.
Protein: YOR1_TTV1K
Sequence: MVDFPDIEVESIPEEIMEEVGEYIDIFIQLTEIAEMERDVIVEEQLKDEAKQFEEYEDFWFDVYT
What are the official names of this protein?
Uncharacterized 7.9 kDa protein.
Protein: Y1389_PYRHO
Sequence: MIGGKEKEVFAKIREHLNAVESTLMAFRKLFEVYIRGDVERAEELLKDVEREESRADELRRNIELMLYGGAFLPASRGDYVRLSELIDNVADAAESAAHSLMFAKPIVPKGLEDEIIRLVDESLKTFEYLKGATLALEDSVDDALMLAKKTETQEEDADKIEYDLLRKIFSREDISTYAKLIWNQVITKIGDVADRAEDASDQIMLIAIKRR
What are the official names of this protein?
UPF0111 protein PH1389.
What is the protein family that this protein belongs to?
Belongs to the UPF0111 family.
Protein: LOLB_CUPPJ
Sequence: MPTMNRSRRLALLCLGAPLLLAACASVAPSRGFDAGEGSASRHYTGRFSANYVRYGRDEGVQGSFRWEEQGRNVRLDLLSPLGQTLAVVTATPSGATLDLPNKPPRNAPEVDSLLEEALGFALPVAGMRDWLHGRPAPGRPAKSTRDTEGRLATLAQDGWSVRYVAWQEVPSASQAPAPRPRRIDLEREGGPTPLAVKLVIDPEEAP
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: Y9849_DICDI
Sequence: MNKSSSASTVPPHSTPHTAHSTSSSSLPPLSSTHHTNTSSTSNNNNNSNNNHNHNHHHTTAATTTTSTTGTGTTAATTSTSTSSTIPINTAGIHTSNSNLATATNTPSSSPQVSTSVERRFWMNDRGSRRSSTSLTQQPLTMNRSSNKLHAAVSARDLTRLKQRLSQPRKAKIELAEYDSMDQTPLCAALRNGSHDIVREILFFYQSNKMDINDQDKSGYTPLHVAASHCDDQILMLLLNYEGINVNITNEDKNSALHYFCQKFRSPNCQEPFSIFLKKGVNVNAQNKNGETPLHKSIFNNTVRLLMVNMLLDAGAEVNVLNSRGESPLHFAVRLGREDLVSVLVKAGADITIKGNEKKTCYELSLTIGNQRVINFLKNVQDIFNWLKSIDLEQYWLNFVKEEIFMDLLLDIDERTLDSLGITYSGHRLKIIRNCRILRDQQLLSTANSNVTTGSGSSGSTTTTTTTTTTTSGCGGLNVPENKKVTQLSIESLKSNPPNSMDSTGSISSDDLKESLTNLEHWVIDHSELEYTLKLGSGSSGKVYKGLYKGKEVAVKVLKSITTQSQLEEFKKEFQIMGSIRSQFMVTFYGACIEPKLCMVMEYCSRDSLYHVMNTKKYDIGWDRFFQFTMQMTLGVQCLHNWTPQIVHRDFKSLNLLVNEDWECKVSDFGLSRFNTADNLETLSKIRGTFAYCSPEVAVGNGSLYTTKSDIYSIGIVFWELVTRVINGEYSRPYSEYSHIKMDFQIMLNSKEGLRPTLPQNTPPGLEALYKQCVNQEQTLRPSCEEIIETLNRLRHEYMSSKTTWDSLIRKLPSLSPPPQPTTTTTTTTSSSTSTNNINNNINNNNNT
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0278535.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Protein: ESAA_STAAC
Sequence: MKKKNWIYALIVTLIIIIAIVSMIFFVQTKYGDQSEKGSQSVSNKNNKIHIAIVNEDQPTTYNGKKVELGQAFIKRLANEKNYKFETVTRNVAESGLKNGGYQVMIVIPENFSKLAMQLDAKTPSKISLQYKTAVGQKEEVAKNTEKVVSNVLNDFNKNLVEIYLTSIIDNLHNAQKNVGAIMTREHGVNSKFSNYLLNPINDFPELFTDTLVNSISANKDITKWFQTYNKSLLSANSDTFRVNTDYNVSTLIEKQNSLFDEHNTAMDKMLQDYKSQKDSVELDNYINALKQMDSQIDQQSSMQDTGKEEYKQTVKENLDKLREIIQSQESPFSKGMIEDYRKQLTESLQDELANNKDLQDALNSIKMNNAQFAENLEKQLHDDIVKEPDTDTTFIYNMSKQDFIAAGLNEGEANKYEAIVKEAKRYKNEYNLKKPLAEHINLTDYDNQVAQDTSSLINDGVKVQRTETIKSNDINQLTVATDPHFNFEGDIKINGKKYDIKDQSVQLDTSNKEYKVEVNGVAKLKKDAEKDFLKDKTMHLQLLFGQANRQDEPNDKKATSVVDVTLNHNLDGRLSKDALSQQLSALSRFDAHYKMYTDTKGREDKPFDNKRLIDMMVDQVINDMESFKDDKVAVLHQIDSMEENSDKLIDDILNNKKNTTKNKEDISKLIDQLENVKKTFAEEPQEPKIDKGKNDEFNTMSSNLDKEISRISEKSTQLLSDTQESKSIADSVSGQLNQVDNNVNKLHATGRALGVRANDLNRQMAKNDKDNELFAKEFKKVLQNSKDGDRQNQALKAFMSNPVQKKNLENVLANNGNTDVISPTLFVLLMYLLSMITAYIFYSYERAKGQMNFIKDDYSSKNHLWNNVITSGVIGTTGLVEGLIVGLIAMNKFHVLAGYRAKFILMVILTMMVFVLINTYLLRQVKSIGMFLMIAALGLYFVAMNNLKAAGQGVTNKISPLSYIDNMFFNYLNAEHPIGLVLVILTVLVIIGFVLNMFIKHFKKERLI
What is the function of this protein?
Component of the type VII secretion system (Ess).  Provides together with EssB and other components such as EssC and EssE a secretion platform across the cytoplasmic membrane in the host.
What are the official names of this protein?
Type VII secretion system accessory factor EsaA.
What is the protein family that this protein belongs to?
Belongs to the EsaA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MXL2_CAEEL
Sequence: MSRSRSAAASSSQKPDDMDLMSPDGSASSPSAPNTPATNSGGFSSDRKKATHLRCERQRREAINSGYSDLKDLIPQTTTSLGCKTTNAAILFRACDFMSQLKTDISDADKQLAQLNAQAAALEMIASEYEQMASSVPDAGQSTIQVKMLQLLLDDCFTSFSSQVDFTTYATITRTLLSWVESLAPNAEPFKSTAGKMVTMPFTSP
What is the function of this protein?
Transcription factor (PubMed:17826759).  Binds to the E box motif 5'-CACGTG-3', probably in a heterodimeric complex with mml-1 (PubMed:17826759).  Involved in modulating longevity in response to TOR signaling, dietary restriction, the decline in protein homeostasis associated with normal aging, germline signaling and the insulin-like signaling pathway (PubMed:24699255, PubMed:27001890).  Plays a role in autophagy (PubMed:27001890).  Involved in regulating migration of the ray 1 precursor cells in the male tail, acting in concert with Wnt and semaphorin signaling pathways (PubMed:17826759).  Regulates transcription of genes encoding extracellular matrix (ECM) components which may contribute to the substratum required for migration of the neighboring ray 1 precursor cells (PubMed:17826759).  Required for resistance to oxidative stress (PubMed:24699255).  Involved in promoting infection by the microsporidian pathogen N. parisii, probably acting independently of its canonical partner, mml-1 (PubMed:27402359).
What are the official names of this protein?
Max-like protein homolog 2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion. Note=Only sporadic mitochondrial localization.
Protein: Y339_RICPR
Sequence: MKQNIYSPLVSIIIPVYNGANYMREAIDSALAQTYKNIEIIVVNDGSKDETETIALSYGDKICYLYKENGGCGSALNCGIKNMKGKYFSWLSHDDVYYPNKIEHQINILNKLDNKDVIVYCGYELIDQKSHSLYCVKPDQRYSKEKLDISLFPLLHSLIHGCTLLIPSILFQKIGLFDESLKYTHDYDLWFKFFRVSSIYFDHEVLIKSRIHAAQTTNTALNQLEEYEDLWSGFLKKLTKEEMIMIKGSTHQFLSDIAVFLKKNGYIKSYQLALAMTDQKIIGGFYTSIITEIIYSLRRHGINTTITKIYKWIRKSRK
What are the official names of this protein?
Uncharacterized glycosyltransferase RP339.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: RAFR_ECOLX
Sequence: MSLKAIATTLGISVTTVSRALGGFSDVAASTRERVEAEARRRGYRPNTQARRLKTGKTDAIGLVYPENDVPFNSGVFMDMVSCISRELAYHDIDLLLIADDEHADCHSYMRLVESRRIDALIIAHTLDDDPRITHLHKAGIPFLALGRVPQGLPCAWFDFDNHAGTWQATQKLIALGHKSIALLSENTSHSYVIARRQGWLDALHEHGLKDPLLRLVSPTRRAGYLAVMELMSLPAPPTAIITDNDLSGDGAAMALQLRGRLSGKEAVSLVVYDGLPQDSIIELDVAAVIQSTRSLVGRQISDMVYQIINGASPESLQITWTPIFYPGSTVHSPSF
What is the function of this protein?
The raffinose (raf) operon is negatively controlled by the specific binding of raf repressor to raf operator (rafO) DNA.  Binds raffinose as an inducer.
What are the official names of this protein?
HTH-type transcriptional regulator RafR, Raffinose operon repressor.
Protein: SYY_SYNC1
Sequence: MKSVQEQMAIIRRGAVEILVESELEAKLKKSVETGVPLKVKAGFDPTAPDLHVGHTVLIQKLKQFQDLGHEVNFLIGDFTGMIGDPTGKNETRKALTREEVLKNAETYKQQVFKILDPERTKVVFNSSWMGQMSAADLIGLAGRYTVARMLERDDFHKRFSGQQPIAIHEFLYPLVQGYDSVALKADVELGGTDQKFNLLVGRELQKQEGQVPQCVLTMPLLEGLDGVNKMSKSLGNYIGITEPAKEVFGKVMSISDELMLRYYELLSDVDLAQLQLVRDGVEGKAGGAHPMESKKSLARELVARFYDQAAALRAEEEFVQQFKQKEVPDDIPEVLIDAGEPVWICRLLTDAGLTASNGEARRLVKQGAVKLGGEKIADAGLEVAPAGELILQAGKRRFARIKFLEKK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR2B_MACFA
Sequence: MGDPERPEAAGLDLDERSSSDTNDNEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVQIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF
What is the function of this protein?
Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner.  Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2.  Contains an iron-tyrosyl free radical center required for catalysis.  Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit M2 B.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus in response to DNA damage.
Protein: IF2_ECODH
Sequence: MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_STRZJ
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SK1_ERGCA
Sequence: EQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, ErgCa-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: JPH2_RABIT
Sequence: MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGTRQSTSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPAADGPALPSPAIPRGGFALSLLANAEAARAPKGGGLFPRGALLGKLRRAESRTSVGSQRSRVSFLKSDLSSGASDAASTASLGEGAEGADDAAPFEADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKGTKRRVLPLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAVSRTSHARAKAEAAEQAALAANQESNIARSLARELAPDFYQPGPEYQKRRLLQEILEHSESLLEPPDRGAAGLPQPPRESPQLHERETPRPEGGPPSPAGTPPQPKRPRPGASKDGLLGPGAWNGEPSGGSGGEGSRPATPAAAGAGRRSPARPASEHMAIEALQAPPAPSREPEVALYRGYHSYAVRTAPPAPPPFEDDPQPEAADPDSAPASPATAPGQAPALGNPEPAPESPAKLEPKPIVPKAKARKTEARGLSKTGAKKKPRKEAAQAAEAEVEVEEVPNTVLICMVILLNIGLAILFVHLLT
What is the function of this protein?
Transcription repressor required to safeguard against the deleterious effects of cardiac stress.  Generated following cleavage of the Junctophilin-2 chain by calpain in response to cardiac stress in cardiomyocytes.  Following cleavage and release from the membrane, translocates to the nucleus, binds DNA and represses expression of genes implicated in cell growth and differentiation, hypertrophy, inflammation and fibrosis.  Modifies the transcription profile and thereby attenuates pathological remodeling in response to cardiac stress.  Probably acts by competing with MEF2 transcription factors and TATA-binding proteins.
What are the official names of this protein?
Junctophilin-2, JP-2, Junctophilin type 2.
What is the protein family that this protein belongs to?
Belongs to the junctophilin family.
What are the subcellular locations of this protein?
[Junctophilin-2]: Cell membrane; Peripheral membrane protein. Sarcoplasmic reticulum membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Note=The transmembrane domain is anchored in sarcoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane. In heart cells, it predominantly associates along Z lines within myocytes. In skeletal muscle, it is specifically localized at the junction of A and I bands. SUBCELLULAR LOCATION: [Junctophilin-2 N-terminal fragment]: Nucleus. Note=Accumulates in the nucleus of stressed hearts.
Protein: RL18_PROMA
Sequence: MSTLSRKQKTQKRHKRLRRNLSGTDQRPRLAVFRSNNHIYAQVIDDVAQNTLCAASTLEKEFLSNSKVNASTCAASTAVGEMLAKRALGKGIKQVVFDRGGSLYHGRVKALAEAARQAGLTF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: BBD1_ORYSI
Sequence: MEIINGPVLPRYAAPATGALTSDAKISGQLLRRVHLRRRACGLQGDHYRAARRFFGFPSERHARSGWVWPVCCSYGSSSDGDGAAAADYDASGEEFVNSSVMEAVELRSVSDGFVIKMRDGKNLRCVQNNPRVLRLRDSAPHHAIVLKMEDGSDLLLPIIVMETPSIMLLAALRNIRIPRPTIYNVVKEMTERMGYAVRLVRITEMVHDAYYSRLYLAKIGNEEETISLDLKPSDAINIAFRCKVPIQVNRRIAYNNGLKVVQPTPSESYVSSDQFQCTRLDRPDDQPCFEAQEFDLVRNMLVAAVEERYKDAAQYRDQLFMFRAKKKNMI
What is the function of this protein?
Bifunctional nuclease with both RNase and DNase activities.  Involved in basal defense response.  Participates in abscisic acid-derived callose deposition following infection by a necrotrophic pathogen (By similarity).
What are the official names of this protein?
Bifunctional nuclease 1.
What is the protein family that this protein belongs to?
Belongs to the bifunctional nuclease family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOAC_PSEFS
Sequence: MLTHLDSQGRAHMVDVTDKSVTFREAVAEARVRMLPETLKMIVDGAHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLTGVKVELSADGADSVHIVARCKLSGQTGVEMEALTAASVAALTIYDMCKAVDRGMTIESIRLLEKLGGKSGHFKADQA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: SYA_XANOR
Sequence: MNAPAKFSTSQIRSDFLAFFEGRGHTIVPSAPLVPGNDPTLLFTNSGMVQFKDVFLGAEKRSYVRAADVQRCLRAGGKHNDLDSVGYTARHHTFFEMLGNWSFGDYFKKDAIAWAWELLTQIWKLPTDRLLVTVYHTDEEAFALWRDMIGIPESRIVRIGDNKGAPYASDNFWQMADTGPCGPCTEIFFDHGDHIAGGPPGSPDEDGDRFIEIWNLVFMQFDRQPDGTLVPLPAPCVDTGMGLERLAAILQHVHTNYEIDLFQALIGKASALTGITDLENKSLRVIADHIRACSFLIVDGVLPSNEGRGYVLRRIIRRALRHGWMLGVRQPFFSKMVPTLVELMGEAYPELVVAKDTVARALLAEEERFAETLDAGMKIFDEVASRSQDIIPGADAFRLYDTYGFPVDLTADIARERGMRVDMEGFECAMERQRETARAAGKFGGGVALPADLVASMSPTVFLGYEAYDADALRVVALLKQGRPVERAQAGDEVIVFTDRTPFYAESGGQVGDSGQLNGPGVLIEVADTQKFAGQFHGHVGRISEGTLALGDVLAGGIDVQRRGKTILNHSATHLLHAALREVLGTHVQQKGSLVAPDRLRFDFSHFQPITADELAVIERKVNAEVRTNHGVEVHNMAMQEALDFGAMALFGEKYGENVRVLKMGGYSTELCGGTHVTRTGDIGLFKITSEGGVSSGVRRIEAVTGQGALDYVADEERRLLEAAHLLGGNATEVVDKVRALTERQKRLQRELESLKAKLASGATADLGAAAIDVAGVKVVAVRLEGFDAKALRDAMDRLKQQLGDSVIVLAGASGGKVALVSGVNGSPTGKVKAGELLSNIASQIGGKGGGRPDLAQGGGEDGPALATALDGVPLWVKQHLG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_FRACC
Sequence: MTATVKDELSRLRVAKPCCRRAEMAALLRFGGGLHIVGGRIVVEAELDTGATARRLRREVAEVFGFPSTVAVLAAGGLRRSVRYIVRVERDGEQLARSTGLLDQRGRPVRGLPPQVVTGSACDAAAAWRGAFLAHGSLTEPGRSCSLEVTSPGPEAALALVGAARRLGVQAKSRDVRGVDRVVIRDGDAIGALLTRIGAHDSLLAWEERRMRREVRATANRLANFDDANLRRSARAAVAAGARVQAAMRILGDDAPEHLLAAGRLRIEHAQASLEELGALADPPLTKDAVAGRIRRLLALADKRANALGIPNTEASVSPDLLENA
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.