PharMolix/UniProtQA huggingface dataset:
Protein: ARGJ_AJECH
Sequence: MRNPKSFCVVAGFVRLPKSSLGQVRYYSIPNDVSIPASKGKFIPGSGTYPKGFLVAGAHAGVKESNTQFPDVALICSETPCSAAAVFTTNKFQAAPVQVSKQVLEKRQGAGIRGVVINSGCANAVTGKGGLEDAKMMSAKVDECNGTPSTGPQDTSTLVMSTGVIGQRLPIKKILDAIPTAHSNLASTHSTWLATARAICTTDTFPKLLSRTFTLPSSPNRQYCLAGMTKGAGMIHPNMATLLGILCTDVPISPSALKALLTHAVSRSFNAISIDGDTSTNDTIALLANGAAGGEAITTTSSQDYAAMQTILTSFAQSLAQLVVRDGEGATKFITVRVCNSPSHADAKAIASTIARSPLVKTALYGKDANWGRILCAIGYAQGIAEGTVVPERTSVSFRPVDGSAELKLLVNGEPEAVDEERAARILQDEDLEIVVDLGGGQKGEKGLGGEEGLYWFCDFSHEYVTINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ROC10_DICDI
Sequence: MSGLLDDDEIIQVSPDSIITSSIGSASLNYSVNGADDNKSIPPSSPQQNLLENDTLSPPPPLPTQTINTSSSPPPPTIITTTTTTTTTTAMSPVATTTTSSPTISASPTYITSPSGTRLSGGNTFNAQQLKSLLLASNIPIPPVPTSPTSTPPNLQTNNNNKQDKDKDNETFATLINEELPLTTEEKENIKAQKKDLISSLPEVPLFISPSPTLSRNNNGKRNSGGNKPPLSPIKISSTSAAGDVSPSISLNNSGSGIYNSTSPSGTASTQTLNILSQLQQQQRNGNNNNNNNNNNNYLSSPTMPALNKHSTHGNFHNSVAGYGNNNNNNNNNNKQPQHPMNGNHSPSNGTSGSLSMSGSGIDNGGNNNNNSNTHGSSSNQSSGVTSPIIQSTSPQPPHLTGLNSDSQMPLSSSPTMGYPRGNHNKKTSASAVSSQNRSPLMNSTGVSSSSSGVKQAGAGEKVMQFLGKMSLSKERMSKLVSQSKEQYKTPSSPYQQSTSSSISSGSGTISGHTSPNSLNSVQVVPFEGIFGIPLRVILRYPNESGNQIPSILNSIFTILESSSALSTNRLFYGDYNTSTSNLASSISPISTAANTTIPTISVPTSPNLSSSLSSSSSSGSSGNSSPNIINQLQQQQQPQPTTTTTTNTNTSPHQYLSQKSIKLEVENICNQYDQGIEVSLKKCNVHVVSEILIEFFNRLPEPIISVEFYETLLNYYQTETLLHLMIRKMNNPNKSILCRLMKYLKDIMVYTNFNDVTLELLVERFHKFILRPTIGTIAQSKEISESHLKTIKDIVTMFIQQADILFQSPEERMNTDDAQILYIEEVLTSTQKSQHQSSVGNLWLFHKQIVWRPKVNIDHGEPDLAILFSSILKIVLYTPPQSSSSSSSSSISNSSSASSSSSSTPSISSTSLSSSLKVLPNFTVYCSSDTKTVITFSFQSPSTCKLIYAYINSVTKSISQLNRIIPQKLDMFSLELESLPNEIKQLKDLQELNLNRNKFKLLPGDLARLTSLRTICIEENNLTEISSEMADFLGTRLSNLENVTLSSNRLVVLPPLYTWLKLKTLNISNNYLTKLPIDIFQIPTLEVLRVSNNDLDDNGIPKICTSTKLRSLDLRKNHLTSIPEGIINLVELQVLTLADNQISHLTSDIQKLTSLTELNLNGNQIQSLPPQLLLLTNLKKLYLDNNQLQSISSAIHRMQSLIELRLTNNNISRLPPGIVALKKLNSLELTGNKPLKDNIPEKYIQKGKEGIFSFFSETMRTNVPCYRTRIIMLGDKSTGKSNLIKCLKKLPKSSFSSSSSNLPSLNNLNSNNSNNSGNSKTNILDIQDWQCPINVDGPDGKKKKTITIHLWEFEGMQNDISHVFFVPNIIYTVCFNLSKFGSSKSNEQKITSYLHGINNYDKKATIIIIGTHLDEISSNSKKQVDKVFDCLSLKYKQLFPTLNLVFHAVSTLKSDADGIRKLRRDIKQMIAKNPILKQTYPASFMFLEDYLKEESNLMSPPLVTKKTLQQMARTMELHNEPHFTQLKSLFNSLGSIALFEQFIRMEPGSTPQKTEMIALNPIWIAKAIASLVCFNPQNLPFNVSVSAEEANDASHDSTITGILPHRVLRYVWGTNSKYYVPERFFSLFLSLLESNDLAINIYSLEVNNNNNNNSNGNNVGRGRSGSRSMSIHEANRSNSYFGVNLNNTSSLSSFTSNQKVRNGRSSSFNARVGWALVSSLLAPPPQLSINGNCSISSNSSSSSSSLSNALNLNNISSMIPIIDLPGIWEAFPESPEIHQFSRRFSLDVIPNGLFGRLLSRLMQHAHLYKCWKDLAILVPEIASMSTTSSSSSSSTANSTTTTSATTLQSLASGSSNNTLQQQFREERILVNVDHDSNTIEITIRFIRPSTLSSQVYSIFESLVSKWYKVSFKTFIPCSHCIEKKIVTPHLFKLEECEAQIFKGELGIYCQYKPNNNNSSNDTSSPIASSRSNPKISRKDSKNLIQSNNNDNNNSLSKKDLKELAKQNKEKEKEKEKDKDKEKEKERKVEIYRDDSFLVPIRSLLLDQFSICHFIKEIDYREIEVLPDHSNQNENGTSTQSMMGMYGKQFVNIKVFNAPLLGADFQNNCARILSSFRHEALSLYNFRHSNVLSIIGISMNPIAIITENPTFGSKGSTTLSEYIQDRQKHPEIPWNIKLKIALDIARAMDKLNSHSPPFLLTNLTSSGIILEKSNDHQSSGNGLEIEPFVNAKIIDFSQSSFLPSLFPTSTTPKSYHSPEVLQKLNYHENSDVYSFGIILYELLTRSIAFQDHDRFSNIVISGQRPSIPLDCLPSFADLIKDCWSGEPLNRPSPSKIISQLYTIKKEIESKEHSYKSLASDNNIYSDHPLPSGGSIIYQDKIIHFGGWNNSSKPHSKVFALNLSSMLFEDKLMVVLNNKQSTTYKAFYTHMQSEFNEENLMFYEAIKTFKSLPNQTPDDREIIKIQSKKIYQVFIGENAPKEINLPFLLKKELKNKIDFPDGPSVTVFNDTLTFVISSIEDSFHRFKFTVPTTNKNGWVEIECKGIPPLPMVGHSSILWNNSLIVIGGWFNKARLLNQIHILNLETFEWNQFVCTGDIPPSSIAALNITLHGDYLLAYYERTDSIKQQIFRLSLDSFIWFSLKLSNV
What are the official names of this protein?
Probable inactive serine/threonine-protein kinase roco10, Ras of complex proteins and C-terminal of roc 10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.
Protein: AMPA_AZOSB
Sequence: MEFTIKTATPEKVRTGVLVVGLFADGILPPAAHAVDKASKGKLAQLVKRGDLDEKAGAAVMLHDLAGIAAERVLVVSLGKSAEFSDKAYRDALNSVAKALASGVAKVAAVAIADAELDGRTLAWRLQQATRQIADGAYRFDAPKAGAKDAKKERGARKITLLIGDKVSDELEAAVRRGQAVAEGMALAKDLGNLPGNVCTPAYLADTAEALGKQFKFDVEVLERADMEKLGMGSLLSVAKGSHIPPKFIVMHYKGGKSKAKPVVLVGKGITFDTGGISLKPGAEMDEMKYDMCGAASVLGTFKAIARMALPLNVVGIVPATENMPGGNATRPGDVVTSMSGQTIEILNTDAEGRLILCDALTYAERFKPACVIDIATLTGACVVALGKIPSGLLANDDDLAAELLKRGTESGDRAWQLPLWDEYQDLLKSNFADMANIGGRYGGTITAACFLARFTKAYKWAHLDIAGTAWVSGDAKGATGRPVPLLAEFLVGRAAAKAD
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_AZOPC
Sequence: MGKIIGIDLGTTNSCVAVMEGGKPVVIPNSEGKMTTPSIVAFVGSERKIGDPAKRQAITNPTKTIFSIKRFMGESYDKVQNEINRIPYKVTRGGNDTSRVDIDGRLYSPQEISAMILQKMKKTAEDYLGQEVTEAVITVPAYFGDSQRQATIEAGEIAGLKVKRIINEPTAAALAYGLEKADKDMKIAVFDLGGGTFDISILELGSGVFEVLSTNGDTHLGGDDFDHVIIDFLADEFQRNEGLDLRKDAMAMQRLKEAAEKAKIELSSSTSTEINLPYIMPVDGMPKHLIVTLTRSKFEQLSDKLIRSTVDPCEKALKGAGLTAKDINEIILVGGSTRIPIIQTEVEKIFGKVPSKGVNPDEVVAVGAAIQGAILSGDSNLGEMVLLDVTPLSLGIETMGSVMTKLIEANSTIPIKKSETFTTAADNQPSVEIHVLQGERPLAKDNKTIGKFHLDGIMPAPRGIPQIEVTFDIDANGVVSVSAKDKATGKEQSIRIEASSGLSEAEIKRMKEEATANAEADTKAKERVDKLNHADSVIFQTEKQLKDFGDKIPADKKASIEATLTKLKEAHKAQDLSSIDTIIAEINNTFQAMSQELYNAKAQTNNSAGNNNSAGNNTQNNNNASDNNNNNVTDVDFEEVK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: LIPB_RICCN
Sequence: MIRFITIPDFADYQVTLKLMEDYVNKVISDHKPEIIYLVEHSEVYTAGTNYKQEELLNYGDIPVIYTGRGGKFTFHGPGQRVIYPILNLASPNRHKDLKLYIKMLEEWIINSLNYFGIKAYIIKDKVGIWVKVRKDEFAKIAAIGVRVRKWVTYHGVAINISTDLSKFSGIIPCGLENSLVTSLNQLGIHVEMSEFDKIIQTEFNKIFK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZFY2_MOUSE
Sequence: MDEDEIELTPEEEKSLFDGIGADAVHMDSDQISVEVQETVFLSNSDVTVHNFVPDDPDSVIIQDVIENVLIEDVHCSHILEETDISDNVIIPEQVLDLDTAEEVSLAQFLIPDILTSSITSTSLTMPEHVLMSEAIHVSNVGHFEQVIHDSLVEREIITDPLTADISDILVADWASEAVLDSSGMPLEQQDDARINCEDYLMMSLDEPSKTDHEGSSEVTMNAESETDSSKLDEASPEVIKVCILKADSEVDDVGETIQAVESETDNGNEAEVTDQRTSIHVPRVNIYMLASDSQKEEEDTKVIVGDEDAGGTAADTPEHEQQMDVSEIKAAFLPIAWTAAYDNNSDEIEVQNATASAMLHHDESGGLDRVPKQKSKKKKRPESKQYQSAIFVAPDGQTLRVYPCMFCGKKFKTKRFLKRHIKNHPEYLANKKYHCTECDYSTNKKISLHNHMESHKLTIKTEKTTECDDCRKNLSHAGTMHTEKGVNKTCKCKFCDYETAEQTLLNHHLLVVHRKKFPHICGECGKGFRHPSALKKHIRVHTGEKPYECQYCEYKSADSSNLKTHIKSKHSKEIPLKCGICLLTFSDTKEAQQHAVLHQESRTHQCSHCNHKSSNSSDLKRHIISVHTKAYPHKCDMCSKGFHRPSELKKHVATHKSKKMHQCRHCDFKSPDPFLLSHHILSAHTKNVPFKCKRCKKEFQQQCELQTHMKTHSSRKVYQCEYCEYSTKDASGFKRHVISIHTKDYPHRCDFCKKGFRRPSEKNQHIMRHHKEVGLA
What is the function of this protein?
Probable transcriptional activator.  Binds to the consensus sequence 5'-AGGCCY-3' (By similarity).
What are the official names of this protein?
Zinc finger Y-chromosomal protein 2.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL35A_METKA
Sequence: MSEVKRGVIVNYRMGRHTQDPRQCIIEFEGVESRSEAAQLIGKEVIWKHPETGKVIRGKVVDTHGNNGAVRVRFERGLPGQALGTEVTLK
What are the official names of this protein?
50S ribosomal protein L35Ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL33 family.
Protein: MNTB_LISMO
Sequence: MEIQGLTIAYKQKVAIDNVTLQIASGKLTGIVGPNGAGKSTLLKGMMGLIPREQGQVTLADKPLTYWRKKIAYVPQRSEVDLTFPITVFDMVLLGTYPALGLIKRPGKKEKQLALDALEQVEMTGFMKRQIGELSGGQLQRVFIARALAQHAEIFFLDEPFAGIDMTSEALIMRLLKKLRDNGKTIVVVHHDFHKVAAYFDDIILLNKKLVAHGPVEQTFTEEKIQFAYGDAPVAFAAGV
What is the function of this protein?
This protein is probably a component of a manganese permease, a binding protein-dependent, ATP-driven transport system.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Manganese transport system ATP-binding protein MntB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PNPH_STRCO
Sequence: MANKVKAEIGVIGGSGFYSFLDDVTEVRVDTPYGPPSDSLFLGEVAGRRVAFLPRHGRGHHLPPHRINYRANLWALRSVGARQVLGPCAVGGLRPEYGPGTLLVPDQFVDRTRSRPSTYFDGLPMPDGTVPNVVHVSLADPYCPTGRAAALKAARGREWEPVDGGTLVVVEGPRFGTRAESLWHRAQGWSVVGMTGHPEAALARELELCYTSLTLVTDLDAGAESGEGVSHEEVLRVFAANVDRLRGVLFDAVAALPASGERDCPCGAALGGMDPGIALP
What is the function of this protein?
Purine nucleoside phosphorylase involved in purine salvage.
What are the official names of this protein?
Purine nucleoside phosphorylase, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: HFQ_DESHY
Sequence: MNKAPINLQDTFLNQVRKENMPVTIYLVNGFQLKGLVRGFDNFTVVIEFEGKQQMVYKHAISTVMPLRPINLVAASQASAEER
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: F16PA_ACIBS
Sequence: MSNLTLSQFLQQEKGNLTPELAQVIDTIAATCKTIDQALQKGALAGILGSAGNENVQGETQKKLDVISNDYLIDALKVHPHVGGLASEELDDFTPAQENGEYLVLFDPLDGSSNIDINMCVGTIFSILPAKNAVTQAQDFMQAGTQQVAAGYVLYGPSTMMALTVGNGVAFFTLDPETQTFLLTTENVQVSADTQEFAINASNQRHWEQPVKQYIEELLAGKTSVREKDFNMRWVACMVGDVHRILCRGGIFLYPYDLKDPKKAGRLRLMYEANPMSMLIEQAGGASTTGRVRILEIEPTELHQRVPVIIGSKNEVERVTSYH
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_AKKM8
Sequence: MANTKSALKRIRQTATRTARNRAVTSKLKTLRKKVAAAVETSDKEAAAAAYNTFSSAVDKAAKVGTIPANRAANYKSKAAKAIAKIA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RPOA_ACICJ
Sequence: MLRDTHLALQRNWQSLRKPEKLDIEPGADDTRVATIIAEPLERGFGLTLGNALRRVLLSSLHGAAVTSVRIDGVLHEFSSIAGVREDVTDIVLNIKQIAVRMHGDGPKRMTVSATGPCEVTAGMIQTGHDIEVMNPELVICTLDDGATLGMEFTVESGRGYVPAAANRPEDAPIGLIPVDSIYSPVRRVSYRVEPTRVGQVTDYDRLILNIETNGAVTPEDAVALAARILQDQLGMFINFEEPQRLRAEEPRPELPFNPNLLRKVDELELSVRSANCLKNDNIVYIGDLVQKSEQEMLRTPNFGRKSLNEIKEVLSAMGLGLGMVVQDWPPENIEELVKRSDNPF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SPB4_PICST
Sequence: METKKGSLDWKNLQYDLQPWIKEAIASLGFPTMTPVQAATIPLLSGNKDVVVEAVTGSGKTLAFAIPVLQKVSNRLYDSQEEGEAPEKVKQGHMLAIVLSPTRELASQIQSVFNNVIEYLPEDKIPIKTQLLVGSLSTVRDDLDRFLKDKPHILIATPGRMLDFMSSQYVKMNSVEIAILDEADKLLDFSFEKDVVNILKRLPKQRRTGLFSATISAAGNTIFRAGMNNPVKVAVKSKSTTANSAPSALHISYLMIEPEKKITTLIKLLHDYRYKKCIVYFPTCTSVKHFYSIFQKIVNGNDNTESFKFYSLHGQLATKPRLRTLQSFTDGDVALNKHILMTTDVAARGIDIPDVDLVIQLDPPTDPDVFLHRCGRTGRANKVGRAIVMLNDGSRELDYVDFMEVKGVAMQEMPTPDLNQSDHQQFQDKLRKYMLDDRARHEIAIKSYVGFVRYYTKHMATSIFRYQTLDYLGIAKMYGLLRLPKMPESKYIPNDNMPDDGWLGEPIDMDKYSYADNQQEASRLENLNAEKIKKIADAKRRKELKVKNEAWSSKTETKETKQERREKMKRKREAIEKQIMEESSDDEETKVDWKDIVKSNKKKKANSGSMQGSFDDL
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase SPB4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ASIC3_HUMAN
Sequence: MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAEHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIFTRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLRKDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNYETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQRHSSTNLLQEGLGSHRTQVPHLSLGPRPPTPPCAVTKTLSASHRTCYLVTQL
What is the function of this protein?
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride.  Generates a biphasic current with a fast inactivating and a slow sustained phase.  In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue.  May be involved in hyperalgesia.  May play a role in mechanoreception.  Heteromeric channel assembly seems to modulate channel properties.
What are the official names of this protein?
Acid-sensing ion channel 3, ASIC3, hASIC3, Amiloride-sensitive cation channel 3, Neuronal amiloride-sensitive cation channel 3, Testis sodium channel 1, hTNaC1.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Cell surface expression may be stabilized by interaction with LIN7B and cytoplasmic retention by interaction with DLG4. In part cytoplasmic in cochlea cells (By similarity).
Protein: NUOC_FRATH
Sequence: MSTKLQDHFEKITKILSGFGVEGCISYGEITFSIRDQRDIHLILKKLKKEYLFEQLTDVTAVDYLTYGQSDWQVGKVVSQTGFSRGRQQDFKTAAVDNRFEIIYQLLSMANNVRIRVKCKLKDAQIILVDSVSDLWPSANWAEREVYDMFGIYFNNHPDLRRVLTDYGFVGHPLRKDFPQTGYVEMRYDENLGRVVYEPVEIDDRVNTPRVIRN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KHPA_STRLI
Sequence: MLEEALEHLVKGIVDNPDDVQVASRNLRRGRVLEVRVHPDDLGKVIGRNGRTARALRTVVGAIGGRGVRVDLVDVDHVR
What is the function of this protein?
A probable RNA-binding protein.
What are the official names of this protein?
RNA-binding protein KhpA, KH-domain protein A.
What is the protein family that this protein belongs to?
Belongs to the KhpA RNA-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_CLOBK
Sequence: MKSNFSKFKDFIKYKKVAVVGIGVSNRPLIKFLVKLGAKVTAFDKKHREKLGSISFELEEIGVDLVLGENYLDKLDGYDVIFKTPSMRIDRPEFVKAKESGAYITSEMEEFIKYCPAKVFGITGSDGKTTTTTLVYEMLKREGYRTWVGGNIGTPLFANIEEMKEDHMVVLELSSFQLMTMDVSPEISLITNLSPNHLDVHKDFEEYVWAKKNIFKYQSSNNLLVLNKDDDLTNGMENEALGDVLKFSLVEKVYNGACLSNNKLTIQGKEVCDSKDINLKGRHNIANLLAAFCMVNKYVSIDSMKYVATNFSGVEHRCEFIREVNGVKYYNDSIASSPSRTLAGLNSFEKPVILIAGGYDKKIPFEPLAEGGYDKIKILILMGDTKNKIRSAFEKVISYKKCEMEIVIVNSMEEAVKVADDMAEKGDIITLSPACASFDMYPNFEIRGNEFKNIVNSL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HELD1_ASPFU
Sequence: MESIPLSPFDLQGSFSNIPYAFFYENTQSENDFMPFDFLKGSLWASLQRFPILTGRLRARSTGHIVVEVDAGNPNQPDIRETLCDSVHWSQLKESSFAWDAWPAGVATVGPVATAAADGEIKLLNIHVMRLAQNSGVILFINIPHYVVDGVGYFAFINHWAETMRMQQQQQEQENEARSRFSFDRGIIQRYLPTERAPLDPLTASIYGQRNLLVDWLAWLSPTTLGGLLSKTAAMARGEAHLFRIPRASLDQVHKDVQPYIPASARLSDNDLLVALISKTYIQSQPQPKPPTGFLSWLRPGQGQPESHCTVRIPCDVRRHLKVRERYTGNLLLGMMVRTPLAELARPTSSETLAAAALNVRQSIERVQPGLVAAYHDLIQANPTSHMRPLAFTATRTTTSLVTTSQVRFPMYEADFGSGKPCFVCLTPVFAGSYTMAAILPTPEGREGGVYVLLTSNVEAMQGIKKNQYWNGLVEIIW
What is the function of this protein?
Acyltransferase; part of the gene cluster that mediates the biosynthesis of helvolic acid, an antibacterial nortriterpenoid (PubMed:19415934, PubMed:19216560, PubMed:29158519).  Protostadienol synthase helA cyclizes (3S)-oxidosqualene to (17Z)-protosta-17(20),24-dien-3-beta-ol (protostadienol)(PubMed:19415934, PubMed:19216560, PubMed:29158519).  The synthesis of protostadienol is followed by several steps of monooxygenation, dehydrogenation, and acyl transfer to yield the final helvolic acid (PubMed:19216560).  Following the cyclization to the tetracyclic protostadienol by helA, cytochrome P450 monooxygenases helB1-mediated and helB2-mediated oxidation at C-4 and C-16, acyltransferase helD2-dependent acetylation of 16-OH, oxidation of C-21 by cytochrome P450 monooxygenase helB4, and short chain dehydrogenase helC-dependent oxidative decarboxylation yield the fusidane skeleton (PubMed:29158519).  This intermediate is further modified in three additional steps mediated by the cytochrome P450 monooxygenase helB3, the acyltransferase helD1, and the 3-ketosteroid 1-dehydrogenase helE to give helvolic acid (PubMed:19415934, PubMed:19216560, PubMed:29158519).  Compared with the late stages in the biosynthesis of helvolic acid, enzymes involved in the early stage modifications act in a relatively strict order (PubMed:29158519).  The hydroxylation of C-16 by helB1 and subsequent acetylation by helD2 should occur before the helB3-mediated oxidation of C-21 (PubMed:29158519).  C-4 demethylation in fusidane-type antibiotics proceeds in an unusual manner though it is also achieved by oxidative decarboxylation (PubMed:19415934, PubMed:29158519).  The methyl group at C-4 beta position is oxidized by helB1 and subsequently removed by the short chain dehydrogenase helC (PubMed:19415934, PubMed:29158519).
What are the official names of this protein?
Acyltransferase helD1, Helvolic acid biosynthesis cluster protein D1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: SAG12_ARATH
Sequence: MALKHMQIFLFVAIFSSFCFSITLSRPLDNELIMQKRHIEWMTKHGRVYADVKEENNRYVVFKNNVERIEHLNSIPAGRTFKLAVNQFADLTNDEFRSMYTGFKGVSALSSQSQTKMSPFRYQNVSSGALPVSVDWRKKGAVTPIKNQGSCGCCWAFSAVAAIEGATQIKKGKLISLSEQQLVDCDTNDFGCEGGLMDTAFEHIKATGGLTTESNYPYKGEDATCNSKKTNPKATSITGYEDVPVNDEQALMKAVAHQPVSVGIEGGGFDFQFYSSGVFTGECTTYLDHAVTAIGYGESTNGSKYWIIKNSWGTKWGESGYMRIQKDVKDKQGLCGLAMKASYPTI
What is the function of this protein?
Cysteine protease that may have a developmental senescence specific cell death function during apoptosis, heavy metal detoxification, and hypersensitive response.
What are the official names of this protein?
Senescence-specific cysteine protease SAG12, Cysteine proteinase SAG12, Protein SENESCENCE-ASSOCIATED GENE 12.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Vacuole. Note=Localized in senescence-associated vacuoles (SAVs) with intense proteolytic activity that develop in the peripheral cytoplasm of mesophyll and guard cells.
Protein: TRUB2_RAT
Sequence: MGSSGLARLQGLFAVYKPPGLKWLHVRETVELQLLKGLNAQQPSAPEQHVRFLLGPVEGSEEKKLTLTATSVPSLTTHRLVRGPAFRNLKIGVGHRLDVQASGVLVLAVGHGRSLLTDMYDAHLTKDYTVRGLLGKATDNFCEDGQLIEKTTYDHVTRERLDRILAMIQGSHQKALVMYSNLDLKSQEAYERAVQGVIRPMNKSPMLIAGIRCLHFAPPEFLLEVQCMHETQQQLRRLVHEIGLELKTTAVCMQVRRTRDGFFGLDDALLRTQWDLHSIQDAIQTAAPRVARELRKNLSLMSGHQQQLPSAGQPWASRVQAPL
What is the function of this protein?
Minor enzyme contributing to the isomerization of uridine to pseudouridine (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs) such as COXI and COXIII mt-mRNAs.  As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.  Also catalyzes pseudouridylation of some tRNAs, including synthesis of pseudouridine(55) from uracil-55, in the psi GC loop of a subset of tRNAs.
What are the official names of this protein?
Pseudouridylate synthase TRUB2, mitochondrial, TruB pseudouridine synthase homolog 2, tRNA pseudouridine 55 synthase TRUB2, Psi55 synthase TRUB2.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Note=Localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly.