PharMolix/UniProtQA huggingface dataset:
Protein: RL19_ACIAD
Sequence: MSGKHPLVQAVENAQLKSDIPAFAPGDTVIVQVKVKEGDRERLQAFEGVVIAKKNRGLNSAFTVRKISSGVGVERVFQTHSPVVAKIEVKRRGDVRRAKLYYLRELSGKAARIREKLPARKRG
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ENGB_ANOFW
Sequence: MKITNVEMVISAVKQEQYPAGQLPEFALAGRSNVGKSSFINKMINRKNFARTSSKPGKTQTLNFYRINDAFYFVDVPGYGFAKVSKTEREAWGKMIETYFTTREQLKAALLIVDLRHPPTKDDVMMYEFLKHYNIPTLVIATKADKIPRGKWQQHAKVAKETLRLISDDELIIFSAETGQGKDEAWGALQKWM
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: 1A1L1_MOUSE
Sequence: MFCLPQQESTAPTTCTGSASTQDMDSGYGDGLQGECLRKPDQTQPKLYGVGDPTATFSSDSSCLSSRGRVIKWFWDSAEEGYRTYHMDEYDEDKNPSGIINLGTSENKLCFDLLSWRLTQGDMLHVEPSLLQYPDWRGHLFLREEVAKFLSFYCKSPAPLKPENVVVLNGCASLFSALATVLCEAGEALLIPTPYYGAITQHIYLYGNVRLAYVYLDSKVTGLNTRPFQLTVEKLEMVLQGVSSEGVKVKGLILINPQNPLGDVYSPEELQDFLRFAMRHKLHVIMDEVYMLSVFEESLGYRSVLSLERLPDPQRTHVMWATSKDFGMSGLRFGVLYTENQHVATAVASLCRYHGLSGLVQHQMAQLLRDHDWISQVYLPENHARLKAAHTYVSEELRALGIPFVSRGAGFFIWVDLRKYLCKGTFEEEALLWRQFLDNKVLLSSGKTFECKEPGWFRVVFSDKENRLRLGMQRMRQVLEGQSQVVEDASPCHAQEPQSQPR
What is the function of this protein?
Does not catalyze the synthesis of 1-aminocyclopropane-1-carboxylate but is capable of catalyzing the deamination of L-vinylglycine.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate synthase-like protein 1, ACC synthase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: PSB3_TRYBB
Sequence: MSILTYSGGSCLAMAGKECFVVISDNRLGEQLKTISMEVPKLHVINDGIVMGLTGLRTDQQTFAQKVNFRTEMYKLREERDINGKAFAALVSSMLYEARFGPWFVEPVIGTIDRKTGEVYLCATDLIGAPCEPEDYVCAGTCAESLHGMCEALWRPGLEPEELFEVAAQAMLSACDRDSLSGYGAVAAIVTKDKLVTRLIKGRKD
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-3, 20S proteasome subunit beta-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECA_ECOSM
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_BUCAP
Sequence: MISKKKSNSSNRWLSEHFQDQYVKEAKKQKIRSRSWFKLEEIDKNNRLFKPGMNVLDLGSSPGGWSQYAAKKIGKKGYILACDILPMKKIKGVDFFQGDFCNKKTLNLILTNLSNVNLNLIMSDMAPNITGCSSIDMPRIIEICKTVFTISDHVLSRNGVVLVKSFQGEGFNEFFAQMKNLFSKIKICKPKTSRSRSREIFMLATR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_GLOVI
Sequence: MYISNQIDPEWPRSTGCGPVGAISRATLICNLCALARSRPAMQTLPNSLPTQVTFKGTLEGLRLLIPVALPWEEVVLQLQHRLNAGERLWQGGAVVILEVGERLLDGPQLQAVTEMLTAQQLHLMRVRTVRRQTAVAAAVAGLSVEQQEAPPEENPDKPPALRGLAEPLYLQTTLRSGMSLVHPGTVIVVGDVNPGAEIVADGDILVWGTLRGVAHAGAHGNTRALIFALRLRPIQLRIADRVARASDEPPAAPQPEVAYIQDNTIHIAITTEFARRW
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: BLAB_AERHY
Sequence: MMKGWMKCGLAGAVVLMASFWGGSVRAAGMSLTQVSGPVYVVEDNYYVQENSMVYFGAKGVTVVGATWTPDTARELHKLIKRVSRKPVLEVINTNYHTDRAGGNAYWKSIGAKVVSTRQTRDLMKSDWAEIVAFTRKGLPEYPDLPLVLPNVVHDGDFTLQEGKVRAFYAGPAHTPDGIFVYFPDEQVLYGNCILKEKLGNLSFADVKAYPQTLERLKAMKLPIKTVIGGHDSPLHGPELIDHYEALIKAAPQS
What is the function of this protein?
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring (PubMed:15588826, PubMed:17307979, PubMed:1856163, PubMed:19651913, PubMed:2327760).  It is able to hydrolyze penicillin and imipenem, but is much less active against cephalothin, cefotaxime, meropenem and ceftazidime (PubMed:1856163, PubMed:2327760).
What are the official names of this protein?
Metallo-beta-lactamase type 2, B2 metallo-beta-lactamase, Beta-lactamase II, Carbapenem-hydrolyzing metallo-beta-lactamase, Metallo-beta-lactamase type II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DF162_ARATH
Sequence: MAKQLCSYMFISMFILSAFLALPSAEGGATIKKCVVDVKLSKPCTFQECQPLCLQKYNGNGLCPGDDNNICACVYNC
What are the official names of this protein?
Putative defensin-like protein 162, Putative low-molecular-weight cysteine-rich protein 37, Protein LCR37.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: TTS1_SCHPO
Sequence: MEPKQRVVKPLKERVLPVVKNTQFVWFSGQVIVLISSVLYALQAIPFRSAPPFLFKSAAFGAIVAYAIVLYKTYSPNLTSRASWNKHFFARLMLDDNVQYFILALSMLIDRPILFSLAPYAIYATFHISTYLRSVLLPAIYPNISDAKTASYASRVSNLLNQYTRSQFQPAMQLVASLETFLLFRLFFGVFLRKNSISRLVGYIFFLRMRYTNSHFTRASIKAVSLRMDRLVADNRVPPVIKNAWHTFKTYVSKFGASPVGTAQSRPTASSSTTAPSST
What is the function of this protein?
Required for the correct positioning of the cellular division plane by delimiting the actomyosin ring assembly at the cell equator.
What are the official names of this protein?
Tetra-spanning protein 1.
What is the protein family that this protein belongs to?
Belongs to the PER33/POM33 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Enriched at the cell equator during mitosis.
Protein: NRDJ_AGRFC
Sequence: MRIERRFTKPGQSSYAEIEFRKAVSEIKNPDGSVVFRLADIDVPAQFSQVATDVLAQKYFRKAGVPKLLKKVEENDVPSFLWRSVADEKALKELPEAERYGSETDARQVFDRLAGTWAYWGWKGKYFSTEEDASAFKDELAYMLATQRVAPNSPQWFNTGLHWAYGIDGPGQGHFYVDPFTGKLTKSKSAYEHPQPHACFIQSVEDDLVNEGGIMDLWVREARLFKYGSGTGSNFSYLRGEGEKLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVVVDADHPDIEAYIDWKVNEEQKVAALVTGSKIVAKHLKAIMKACVNCEADNGDCFDPAKNPALKREIRAAKKDMVPENYVKRVIQFAEQGYKDIQFKTYDTDWDSEAYLTVSGQNSNNSVSLKDDFLRAVENDGNWNLTARKDGKVMKTLKARDLWEKISHAAWASADPGLHFNTTMNDWHTSPAEGPIRASNPCSEYMFLDDTACNLASLNLLQFKDAKTKRIDIADYEHAVRLWTVVLEVSVMMAQFPSRQIAERSYEYRTLGLGYANIGGLLMSSGIPYDSDEGRAIAGALTAIMTGVSYATSAEMAGELGPFPSFAPNRDNMLRVIRNHRRAAHGQSEGYEGLSVNPVALIHADCTDQDLVAHATAAWDKALELGEKHGYRNAQTTVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLAGGGYFKIINRAVPESLRSLGYSESQIAEIEAYAVGHGNLNQAPAINPSTLKAKGFTDEKIEAVNAALKSAFDIKFVFNQWTLGADFLKGTLKVSDEQLSDMSFNLLDHLGFAKKDIEAANVHVCGAMTLEGAPFLKNEHLAVFDCANPCGKIGKRYLSVESHIRMMAAAQPFISGAISKTINMPNDATVEDCGAAYMLSWKLALKANALYRDGSKLSQPLNASLVEDEDDEDFVEELIQQPLAQQAVTITEKIVERVIERVSREREKLPNRRQGYTQKATVGGHKVYLRTGEFGDGRIGEIFIDMHKEGAAFRAMMNNFAIAISLGLQYGVPLEEYVEAFTFTKFEPAGMVQGNDAIKNATSILDYVFRELAVSYLGRHDLAHVDTSDFSNTALGKGIQEGKTNLLSTGWTRGYKPTLVSSNEGDRAASEPKGSATAAPARGSANVTSFAGSAARKLEPTVAITTSEIVSFKRDYEERAKELAEEIAEEVIDEVVQEAQQTATALFSDKAAADAASAKAEAKKKENERRMRSIAQGYTGNMCSECQNFTMVRNGTCEKCDTCGATSGCS
What is the function of this protein?
Catalyzes the reduction of ribonucleotides to deoxyribonucleotides.  May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen (By similarity).
What are the official names of this protein?
Vitamin B12-dependent ribonucleotide reductase, Ribonucleoside-diphosphate reductase NrdJ.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase class-2 family.
Protein: PURT_MARN8
Sequence: MGTPLKSNSFRVLFCGSGELGKEVVIELQRFGVEVIAIDRYADAPAMQVAHRSHVVDMLDPVALRSVIEKERPNLIVPEIEAIATPELVKLEQEGYRVIPSARAVNLTMNREGIRRLAAEELGLPTSPYRFAGTREEYLQAVAEVGLPLVVKPVMSSSGKGQSTVKTEADIERAWEYAQTGGRAGKGRVIVEGFVDFDYEITLLTVRHKEGITFCEPIGHRQEDGDYRESWQPQPMNDLALQRSKEIARAVVEDLGGYGIYGVELFVKGENVWFSEVSPRPHDTGLVTLVSQDLSEFAIHARAILGIPVPVVRQNGPSASAVILPEGSSTEVSYTGLEEALAQPGTQLRLFGKPELQGRRRMGVALALGSSIEDAREKARTAASSIKVQF
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: NTPPA_CLOB1
Sequence: MKNIILASASERRQELLKRILEDFQIIVSDFDESSAPFKDNIPSYVMNLAEGKARSVSKKIMDQDSNLVIGCDTLVAFNNKVLGKPKDKKDAFEMLQALSGNEHEVYSGLAILDVKSNKIITDFVCTKVKFSKLTSLQIEKYINTGDSMDKAGAYGIQGKAGVFVENINGCYYNVVGLPLNKLNSMLMEMGVNL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM10B_DANRE
Sequence: MEEQLRVGGCSPDGGFTIVNEAPVADLLEFLHIDVELEHARDDREESARSKNVMRKQRNWERRLEVKKSKRKEEKLRKKLNRQDKDVSDAQLSKRVIKAITKERLEGARAAGLRLCVDLSMTEHLTHKEISRLAAQIRRLYGSNKKALQPFHVFLTELQEDSLLYKECVGMNDGFMHYLIDVTEESWFHLFPSEDVIYLTPDASEALESVEEDKIYILGGLVDETIHKKISYTKAKELGVRTARLPIDEYMVKKENPKNFHSKILAINQVFDILLTFRDTRDWTKALMAGIPPGKGFVLASAASKPLEET
What is the function of this protein?
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs.  Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs.
What are the official names of this protein?
tRNA methyltransferase 10 homolog B, RNA (guanine-9-)-methyltransferase domain-containing protein 3, tRNA (guanine(9)-N(1))-methyltransferase TRMT10B.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
Protein: ACYP_LEGPC
Sequence: MTKELCMRCYISGRVQGVWFRASAKKLAEQLMISGWARNLADGRVEVFACGKEDKLEEFYTWLQKGPLNARVDVCTRENLPWEDYISFDVL
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: DUS1_SYNY3
Sequence: MGKCSYRFISLQTLTPNSLLDHSPNPTIWAKPLQIGSLTLHSRVLQSPLSGVTDLVFRRLVRRYAPQAMLYTEMVSATEIHHLRTLPQVMEIDPRENPISIQLFDCRPDFMAEAAQKAVAQGAQSVDINMGCPVNKITKKGGGSSLLRQPAVAEAIVKTVVAAVDVPVTVKTRLGWDDGEINIVEFAQRLQDAGAQMLTLHGRTRAQGYNGRARWQWIAKVKQALTIPVIANGDIFSVEAAIACLEETGADGVMCSRGSLGYPFLVGEIEHFFKTGEKRKAPTVAEKLTCAQEHLQMLWEYKGQRGLFQARKHLAWYCKDFPGAAALREQLFQINSVQEGKDLLDQAISTAKLCL
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase 1.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: END4_CHLAD
Sequence: MPRFGAHMSISGGVSKSFARGESVGLDAMQIFAKNERQWTAKPISAEEMAAFQAEQQRTGIHPVIVHDSYLINLAAPADDLREKSIVAFADELERCAQLKIPYLVTHPGAHTGIGEEAGLVRVADAISRLLAEGVGGTTMILLETTAGQGTALGYRFEHLARLFELIPYHDRLGVCVDTCHIFAAGYDIRDPDTYDATFAELDRLVGLERVKCFHLNDSQKDLGSRVDRHAHIGQGCIGTEAFRLLVNDPRFAHLPMIIETPKGEDMAEDRMNLALLRSLVRITAA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: AKR2A_ARATH
Sequence: MASNSEKNPLLSDEKPKSTEENKSSKPESASGSSTSSAMPGLNFNAFDFSNMASILNDPSIREMAEQIAKDPAFNQLAEQLQRSIPNAGQEGGFPNFDPQQYVNTMQQVMHNPEFKTMAEKLGTALVQDPQMSPFLDAFSNPETAEHFTERMARMKEDPELKPILDEIDAGGPSAMMKYWNDPEVLKKLGEAMGMPVAGLPDQTVSAEPEVAEEGEEEESIVHQTASLGDVEGLKAALASGGNKDEEDSEGRTALHFACGYGELKCAQVLIDAGASVNAVDKNKNTPLHYAAGYGRKECVSLLLENGAAVTLQNLDEKTPIDVAKLNSQLEVVKLLEKDAFL
What is the function of this protein?
Exhibits chaperone activity toward chloroplast outer envelope membrane, mitochondrion outer membrane, endoplasmic reticulum membrane and peroxisomal proteins, by recruiting specific proteins containing a single transmembrane associated with an AKR2A-binding sequence (ABS) and subsequently binding glycolipids (e. g.  monogalactosyldiacylglycerol (MGDG) and phosphatidylglycerol (PG)) present in the membrane of the target organelle (PubMed:18193034, PubMed:20215589, PubMed:25203210).  Seems to be involved in the regulation of hydrogen peroxide levels during biotic and abiotic stresses by optimizing the ascorbate peroxidase 3 (APX3) hydrogen peroxide-degrading activity.  This regulation might be monitored by GRF6.  Cytosolic targeting factor for chloroplast outer membrane (COM) proteins that mediates sorting and targeting of nascent chloroplast outer envelope membrane (OEM) proteins to the chloroplast.  Facilitates the targeting of OEP7 to chloroplasts (PubMed:18193034).  Facilitates the targeting of APX3 to peroxisomes.  Involved in cellular metabolism (e. g.  peroxisome activity) and required for plant growth and development (PubMed:20215589).
What are the official names of this protein?
Ankyrin repeat domain-containing protein 2A, AtAKR2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Plastid, chloroplast outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: U1159_ARATH
Sequence: MNPANFQPPNPPFHWAPMLPPDPPRCGMFWNTKNITDQLKQLQDTLNLAKSMEKELEALKMIKDAKGSVENAVQDSGVEYLEARKMDLGQQEMLSVDAANSLMSTLRAQLEPFRFVVDENSPWEEKSAAVRLTCKMKKSIRNKLWKKRKRRCAAEMRAKEPERFEQADREADEWREKEMAKDMANRKVDEMKAIEKIKAKRERKRLEPELELALIVEEMQELRSLRIEKLKKQGHFLPEEDDKFFESVRAAVEQEENQAQSLINTETEEHVIASEENTTLTTSNKTNNDTDKDSNTNAASCERTMKAPDNGCDNISNLPVEVYHYYYGSNIDMGRLIEIRREWDAYLSAGGSRIPGHWVQPSPPANEIWASCLVNTPKRDLS
What are the official names of this protein?
U11/U12 small nuclear ribonucleoprotein 59 kDa protein, U11/U12 snRNP 59 kDa protein, U11/U12-59K.
What are the subcellular locations of this protein?
Nucleus.
Protein: FTSW_CAUVN
Sequence: MASNATHAFARTDRTALGLWWWTTDRWLLGATALLVTLGMLLSFASSPAAAQRIGIDDQFHFALRMCFFATASSVLMLITSMLSPRDIRRAAFFIYLGAIAVMIALPFIGHNAKGATRWLQFAGFTLQPSEFMKPALIVLVSWMFAEGQKGEGVPGVSIAFLLYFIAVALLLIQPDVGQTVLITIAFGAAFWMAGVPISWIMGLGGVALAGLGSTYFLFDHVHARVQKFLSPDQADTHQITRAAEAIRAGGLFGRGPGEGVMKRHVPDLHTDFIYSVAAEEYGLIFSWSLIGLFAFVVVRGLYKAMKLNDPFEQVAAAGLFVLVGQQALINIAVNLNMIPTKGMTLPFISYGGSSMLAMGLTLGMALALLRKRPGAYGASGEFGFGRADA
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: M4A6D_MOUSE
Sequence: MIPQVVTSETVTVISPNGISFPQTDKPQPSHQSQDSLKKHLKAEIKVMAAIQIMCAVMVLSLGIILASVPSNLHFTSVFSILLESGYPFVGALFFAISGILSIVTEKKMTKPLVHSSLALSILSVLSALTGIAILSVSLAALEPALQQCKLAFTQLDTTQDAYHFFSPEPLNSCFVAKAALTGVFSLMLISSVLELGLAVLTATLWWKQSSSAFSGNVIFLSQNSKNKSSVSSESLCNPTYENILTS
What is the function of this protein?
May be involved in signal transduction as a component of a multimeric receptor complex.
What are the official names of this protein?
Membrane-spanning 4-domains subfamily A member 6D, CD20 antigen-like 8.
What is the protein family that this protein belongs to?
Belongs to the MS4A family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: OTCC_CLOP1
Sequence: MAVNLKGRSFLTLKDFTPAEIRYLLDLSHDLKAKKRAGILGDSLKGKNVVLLFEKTSTRTRCAFECGAAEEGAHVTFLTNSQMGKKESIEDTAKVLGRMYDGIEFRGFKQSTVEELAKHAGVPVWNGLTDADHPTQILADFLTIEEHAHKPLSEIKLVFTGDTRNNMSYALMYGAAKMGMHFVALGPDSLKPDEDILKEMQEYSKETGATIEFSSNVDEAVKGADVIYTDIWVSMGEDESLYPERVKLLTPYKVTREMMNKTGNKNTLFMHCLPSFHDEDTEVCKDMMDRLGLDIREVEDEVFRSKNSVVFDEAENRMHTIKAVMVATAGR
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_ANADF
Sequence: MTEKITPEVVAQHGLTQAEYDEVKRHLGREPNLTELGVFSVMWSEHCSYKSSRVHLKTFPTSGPRVLQGPGENAGVVDLGDGLAAAFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPIASANSLRFGDPSHPKTAYLLEGVVAGIGGYGNCMGVPTVAGEVMFHPSYNGNCLVNAFTLGILPADKIFLGTAAGVGNPVMYIGAKTGRDGIHGATMASAEFDASTEEKRPTVQVGDPFMEKLLLEACLELFKTDAVVGIQDMGAAGFTSSSVEMAGRAGNGLDLFLDQVPLREEGMTPYEILLSESQERMLLVAAEGKEDMVRKICTKWDLDVAIVGRVTGTGRWRAHWHGKVVADLPVDPLTEGAPKYQRPMTPHPALPALHAFDLSTVPEPADLGDTLLRLLARPTIASKEWVYQQYDHMVRLVGAVRPGGDAAVVRIATGDERHAGKGIAISVGANGRYCFLDPHLGAQHAVAECARNIACVGGEPIAVTDCLNFGNPEKPEIMWQFAECVRGIGDACRALGTPVVSGNVSLYNETEGQGILPTPTIGMVGLLPDVEKTCTSAFKNAGDVIALVGTLQGEVGGSEYLSAEHGREAGHPPALDLAKEKAVQETVRRAVREGLLSSAHDCSDGGLAVALAECCMMHGVPAGAEKAPWIGAAVRVPFPARKDFVLFGEDASRILVSMPKESAARFVALAQECGAPVIRLGAVGGDTLEIQGALSVPVAELAKAWRDGVPAVLRRDVGHAAASGIAREPQEPLP
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBAB_SHIFL
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HIS8_PELUB
Sequence: MTVPKFKKFKIEAYKPGKSNIAKIRNIIKLSANESALGVSPRVKKILQNKKLLISKYPDGKAKNLRKEISKKFKCDFERIICGAGSDEIIQMICQLYLKPSDEVIVPQYSFLMYRIYAQIVGAKVVFSKEKNFKVSINEIIKKVTRKTKLVFIANPNNPTGTYLTRAELIDLRKKLNKNILLVLDDAYFEYMKNKDYKSGLDLFKNKDNVVVIRTFSKIYGLASLRVGWGHGPKKIISAMNLIRPPFNVNQVAQMAAIEALKDRKFINNSVKHNIREANKVRNALQKLKILSNEVTANFLLLNFDRCKFSANYIFNKLQSKGIILRSTEDGYNIKNKLRLTIGSTKENMRFITTIKAIFN
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ILVD_RHIEC
Sequence: MPAYRSRTTTHGRNMAGARGLWRATGMKDSDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPTVFVSGGPMEAGKVVLHGKQHALDLVDAMVAAADDKISDEDVKVIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHADRKRLFVEAGHLIVDLARRYYEQDDVKALPRTIASKQAFENAMALDIAMGGSTNTVLHILAAAHEGEVDFTMADIDALSRRVPCLSKVAPAKSDVHMEDVHRAGGIMSILGELDKGGLLNRDCPTVHAETLGDAIDRWDITRTTSDTVRDFYRAAPGGIPTQVAFSQEARWDELDTDRQNGVIRSVEHPFSKDGGLAVLKGNLAVDGCIVKTAGVDESILKFSGPARVFESQDASVKAILANEIKAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALITDGRFSGGTSGLSIGHVSPEAANGGTIGLVREGDIIDIDIPNRTISLRVGEAELAARRAEQDARGWRPTEVRKRNVTTALKAYAAFATSADRGAVRDLDAR
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CSPL9_ARATH
Sequence: MMNVSRPAIHPVDALPVAPTAGAIDRPPVRMKDVQGMPGTTGGLILRLSQFVPALISVSVMVTTSDFRSATAFCCLVLAVSLQSLWSLSLFIIDAYALLVRRSLRNHSVVQCFTIGDGVTSTLTFAAASASAGITVLINDLGQCNVNHCTRFETATAMAFISWFAVSPSFILNFWSLATH
What are the official names of this protein?
CASP-like protein 5A1, AtCASPL5A1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.