PharMolix/UniProtQA huggingface dataset:
Protein: PYRE_CLOBA
Sequence: MEAYKKEFIEFMIECGVLTFGDFVTKSGRKTPFFVNTGNYKTGSQLKRLGEYYAEAIKANYKDDYNIVFGPAYKGIPLSVTVTMALSDKYGIDVSYCSNRKEVKDHGDTGILLGSKLNDGDKVLIVEDVTTSGKSIYETMPIIKEQGNVDVVGLVISVNRMEKGQGEKSALVELEEKYGFKSCAIVTMTEVVEYLYNKEVNGKVIINDEIKTRIDEYYKEYGAK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CISY1_AEDAE
Sequence: MALSRIYSSKLASANKNLLPVITTYVRNASDSTDLKAVLSEKIPKEQERVKNFRKQFGATKVGEVTVDMMYGGMRGIKGLVCETSVLDPDEGIRFRGLSIPECQKVLPKAPGGAEPLPEGLFWLLITGDVPTKAQVDALSREWANRAALPSHVVTMLNNMPTTLHPMSQLSCAVTALNHESKYAKAYSEGVHKSKYWEYVYEDSMDLIAKLPVVAATIYRNTYRDGKGIGAIDPKKDWSANFTKMLGYEDEQFTELMRLYLTIHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGMNGLAGPLHGLANQEVLVWLQKLRKELGDNASEDKVKDFIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPLFQLVSNIYKVVPPILTELGKVKNPWPNVDAHSGVLLQYYGLKEMNYYTVLFGVSRALGVLASLVWDRALGLPIERPKSMSTDGLMKAVGASK
What are the official names of this protein?
Probable citrate synthase 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: EPSI_BACSU
Sequence: MSLQSLKINFAEWLLLKVKYPSQYWLGAADQPVKAAAHQKKIILTLLPSHDNLGDHAIAYASKAFLEQEYPDFDIVEVDMKDIYKSAKSLIRSRHPEDMVFIIGGGNMGDLYRYEEWTRRFIIKTFHDYRVVQLPATAHFSDTKKGRKELKRAQKIYNAHPGLLLMARDETTYQFMKQHFQEKTILKQPDMVLYLDRSKAPAEREGVYMCLREDQESVLQEEQRNRVKAALCEEFGEIKSFTTTIGRRVSRDTREHELEALWSKLQSAEAVVTDRLHGMIFCALTGTPCVVIRSFDHKVMEGYQWLKDIPFMKLIEHPEPERVTAAVNELLTKETSRAGFPRDVYFKGLRDKISGEAQ
What is the function of this protein?
May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation.  EPS is responsible for the adhesion of chains of cells into bundles.
What are the official names of this protein?
Putative pyruvyl transferase EpsI.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide pyruvyl transferase family.
Protein: Y1310_RHIME
Sequence: MNIKWLGHSAFHIETAKAKILIDPFFTGNPAFRDEERKAATAGLTHILLTHGHGDHVGDTVAIAKETGATVLANFDLCMWLGRQGISKLEPGNTGGTIQLGSFTATFVNALHSSAQITDDGVSHSLGNANGLVLHFDDEPTLYHMGDTEIFSDMALVQELHEPEIGIVPIGDRFTMGGAVAALACQRYFKFNTTIPCHYGSFPIIDQTPETFIAGMDGASTLVATPEVGGAVTL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase R01310.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: PYRE_BACCN
Sequence: MKKEIASHLLEIGAVFLQPNDPFTWSSGMKSPIYCDNRLTLSYPKVRQAIAAGLEELIKEHFPTVEVIAGTATAGIAHAAWVSDRMNLPMCYVRSKAKGHGKGNQIEGKAEKGQKVVVVEDLISTGGSAITCVEALREAGCEVLGIVSIFTYELEAGKEKLAAANVASYSLSDYSTLTQVAEEKGMIGQAEMKKLQEWRKNPADEAWITA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: LPXA_ANASK
Sequence: MAIHPTAIVEAGAQVDPSCEIGPFAVIGPLVRMGPGNSVGPHAVVTGRTTLGASNRIFPHAVIGGIPQDLKYRGEDTALVIGDRNTFREFATVNLGTAGGGGVTRIGSGGLFMASSHIGHDCQVGDGAIIANSVAIAGHVLIEDHVHFGGLSASHQFCRVGRLAFVGGMTGVAMDVAPYCTVAGARGELAGLNAIGMQRAGLTEEQIGRVKQAYKIVFRSSLGLAEAIAQLEAELAGHPETDHFIAFLKGSQRGITR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBHB_PSEAE
Sequence: MNKSELIDAIAASADIPKAVAGRALDAVIESVTGALKAGDSVVLVGFGTFAVKERAARTGRNPQTGKPIKIAAAKIPGFKAGKALKDAVN
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: EFTS_ECODH
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKGADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PREA_PORPU
Sequence: MATSSSLFHPIEKELYSVEHNLKSVAGTRHPILYAAAKHLFEAGGKRLRPAIVLLVAKSTSEQQEIKPGQRRLAEITEIIHTASLVHDDVIDECSTRRGEKTVHKLFNTKIAVLAGDFLFAQSSWYLANIGNLEVVKVITKVITDFAEGEIRQGLVHFDPSISIDDYIEKSFYKTASLVAASCRGAAMLNDLNSQMHNDLYLYGKHMGLAFQIMDDVLDIAGSTKSLGKPSGADFMNGNLTAPILFALTQEGKLDQLIQREFSDERDISLALFLIKKSGGITKAKDLAKEQVQAALCCLQFLPKSAPVSSLKELTHFIITRLS
What is the function of this protein?
Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate.
What are the official names of this protein?
Prenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MTS30_SELML
Sequence: MECLMAKLVPRLELPLLPNNIPSACHWDSSSLSQELDQWLISKLGITDESAKRKIVQSRVMLLACLMHPNGERDRVLLAGKHLWVYFLVDDILESSSREGYGALKSIVWSIATTGIYKASEEHDHHDLVLLLLVEVMVELRKEMPTSLFARYCKILSIYLDSVQEEVKHQINNTIPSSEEYRLLRRRTGFMEVMACIMTEFCVGINLEELVVNLGEIRELVKIMDDHIVTVNDLLSLRKEYYNGTIYHNWVIVLLAHDCATFQKSVDRVCEMIKQEEDSILDLQKKLIIKAKVDKNPELLKFAFNVPMAVAGHLKWAFITARYHGCDNALLDGELFHGTWIMDPNQTVIVKNM
What is the function of this protein?
No terpene synthase activity detected in vitro.
What are the official names of this protein?
Microbial Terpene synthase-like protein 30, SmMTPSL30.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: SYS_VIBC3
Sequence: MLDSKLLRTELDETAAKLARRGFKLDVETIRTLEEQRKSIQVEVENLQSTRNSISKQIGQLMASGDKAGAEAVKQQIGTLGDDLDAKKVELDAVMAQLDAITQTVPNIPDDAVPNGKDDSENVEVSRWGTPKTYDFEVKDHVDLGEMGDGLDFASATKITGARFVVMKGQFARLHRAIAQFMLDLHTDQHGYTELYVPYLVNAETLFGTGQLPKFGQDLFHTEPLTEKASDEEPRRLSLIPTAEVPVTNLVRDTILDEAELPLKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQITRPEDSMAALEELTGHAEKVLQLLELPYRKVILCTGDMGFGSCKTYDLEVWVPAQKTYREISSCSNMWDFQARRMQARFRRKGEKKPELVHTLNGSGLAVGRTMVAILENYQEADGRIAIPAVLQKYMGGLTHIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBM_MORIN
Sequence: MEVNILAFIATALFILIPTAFLLIIYVKTVSQSD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ACFR1_ARATH
Sequence: MAVRINAMAVTFVAHALAVIAAIMVLVWSISYRGGLAWEATNKNLIFNLHPVLMLIGFIILGGEAIISYKSLPLEKPVKKLIHLILHAIALALGIFGICAAFKNHNESHIPNLYSLHSWIGIGVISLYGFQWVYSFIVFFFPGGSTNLKSGLLPWHAMLGLFVYILAVGNAALGFLEKLTFLENGGLDKYGSEAFLINFTAIITILFGAFVVLTASAESPSPSPSVSNDDSVDFSYSAI
What is the function of this protein?
Two-heme-containing cytochrome.  Catalyzes ascorbate-dependent trans-membrane ferric-chelate reduction.  Able to use dihydrolipoic acid (DHLA) as an alternative substrate to ascorbate.
What are the official names of this protein?
Transmembrane ascorbate ferrireductase 1, Cytochrome b561, Artb561-1, AtCytb561, Protein b561A.tha5, Tonoplast Cyt-b561, TCytb.
Protein: HIS4_BUCBP
Sequence: MIIPSIDLIEGNIVRLYQGNYDTKTFYQNNIYDIALKYYNQGAKIVHLVDLDGALCPNNKQTSLIKNLLNYFNFHIQVGGGIRSYKDVETLLLNGAKRVVIGSSAINNITEVEKWLLEFGYKSIVLALDVYVRNNGYKEVVINGWKNRSNVSLESVLERFSTLGIKYVLCTDVKKDGTCLGPNFTLYKNISKLFKNVCFQLSGGIGTISDVISAKKSGIKDIIIGRALLENKFSLLEAIRC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_ECO45
Sequence: MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGE_RHIME
Sequence: MSLYGTMRTGVSGMNAQSNRLSTVAENIANANTTGYKRASTEFSSMILPSGNGSYNSGGVQTEVRYSISQQGATTFTTSASDLAIDGGGFFIVEGANGQEYLTRAGSFVPDSEGNLVNASGFTLMGYEYEAGVDPTVVVNGFDGLTRVNLASDGLIAAGSTKGSMGANLPSGAPVGDVSTTSLVVYDSQGNTRILDFNYEKTGANAWTLEIVDRASGDALTVPPVTLAFNAAGELTTSPATVVANGALIVPPPATGAVVGSITIDFSKTTQLGYAFNADGGSIDGNAPSKVAGYQIDSDGIVYVKYENGKLDPRYRIALANVQSPDKLRPESGNVYSQGVDSGVIITGFAGSGDFGEILSGALESSNVDIAEELTAMIESQRNYTANSKVFQTGSELLEVLVNLKR
What are the official names of this protein?
Flagellar hook protein FlgE.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: PHS_RAT
Sequence: MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT
What is the function of this protein?
Involved in tetrahydrobiopterin biosynthesis (PubMed:8444860, PubMed:8618906).  Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (PubMed:8444860).  Coactivator for HNF1A-dependent transcription (PubMed:1763325).  Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity (PubMed:1763325).  Also acts as a coactivator for HNF1B-dependent transcription (By similarity).
What are the official names of this protein?
Pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Dimerization cofactor of hepatocyte nuclear factor 1-alpha, DCoH, Dimerization cofactor of HNF1, Phenylalanine hydroxylase-stimulating protein, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Recruited to the nucleus through the interaction with HNF1B.
Protein: RL22_ECOSM
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: TTI1_SCHPO
Sequence: MSHIQSIFAQIRDPFRKLSFYSLPLSSETSSVDSNGLKNSLKDAYFGLEKALTNTDADLPLNLCDYIFFPIVPVLKSWYRVPSTGVEYAIQCVNLLYKHGWREAHNEMLTMQLLLMLLNIADGWKSPSETVEQDFRVREITFETLENVITDFKPNFHDKRQYLLFARALSSALDIIPNKNSSRRLQFASLCCVQKLICPKQYRLPTEFLTTFLPGIVSGLTKGLAPNGTCQYFKNVCISLNILGDTVVKAISDDNTKDLPDEKDASSNSHFFGPTKRTKSWKRATCQQLSNAVKAILHLRSSQNLHVQDALFDFCFILFRDCLDSLKDCRIHLLESMLKLINKKENPKLRDYGMNKLVSLIESFNNITMESVLTECLNDWSTTWSSVSTFASEDNKLEELNRLKSLLSISSHLPKTLQLMEPLLDGILSQLVPKSSGIDSNSQKLLTSSTSNEYIHGEFFGGNEMERTTQEIVTSFAKAPNVKYVMQSLLSKATSATNENSVRAFWAFMVLLKSDVETVDSLEMYIDSLEQYSFEVLQQLSQLNVFTKASLEDKQKKEKYNLLCVRSCIAIDSISWISSLQGVKFRSKLMAYFYPLLEHLAFASPYVSSFAEACIQAIATNCNYSTPAELLRENIDYVVNSVALKLNTLDVSPQLPIVMAYVIKNDDGGCIRYIGDVVDAIFGILDAYHGYARLTEGLLGILYAIIKQESINGEEKKLIVGVEEDAMNEDKNKPCKKIREFVQLLLENPNYPLPKDDHELEDMIHDEQQETKSGHEQFREHAMKEKEKKGKENENMGETTVDHENINSNVMDEQGEKQKDDVVDMVRKITEKAQLFLSHEQITIRVEMLKLLSYGSNVLAKEPNTFYPAINTFWPLVVIQLDTDNELLVECALETIYQVCALADDFMTSRIRQDLLPRLETLCQRWHLFNVARTYSSEHRLQRAMLKVTSACVANKLSIVVYLKLMGITAPIIRAITHMSQKYAGDESLVEETWNAFSKQNPDAVYYEREVRGSQMIDTFSTELLIPGKQRVQRTYRRTHEVLEPVGAKTSETVFNDLLGQQGSGKTETQEEPLPSLDNLLHLNQPKKGAKKPLISII
What is the function of this protein?
Component of the TORC1 and TORC2 complexes required for the regulation of the cellular respons to changes in available nutrients.
What are the official names of this protein?
TEL2-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the tti1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIVG_SCHPO
Sequence: MSANLQNENPEVKELNQLPSRVEEEEDLLLSSTKQWLTEIESEQTNIKEERDPIDPQEIYDLLAKINDPEHPLTLAQLSVVKLEDIEVVDNVEGDSYITVHITPTIPHCSMCTLIGLCIRVRLERCLPPRFHVDVKVKKGTHASESQVNKQLNDKERVAAACENEQLLSVLNGMMATCV
What is the function of this protein?
May play a role in chromosome segregation through establishment of sister chromatid cohesion.
What are the official names of this protein?
MIP18 family protein C144.16.
What is the protein family that this protein belongs to?
Belongs to the MIP18 family.
Protein: TBA1A_PIG
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRAHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:7225365).  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (PubMed:7225365).  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:7225365).
What are the official names of this protein?
Tubulin alpha-1A chain, Alpha-tubulin 1, Tubulin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HSLU_MANHA
Sequence: MSMTPREIVSELDAHIIGQKDAKRAVAIALRNRWRRMQLPEDLRQEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLADVSMKLVRQQAVEKNKMRAQDAAEDRILDVLLPPAKDQWGNVQESDNNSTRQTFRKKLREGQLDDKEIEIDVAAQVSVEIMTPPGMEEMTSQLQSLFEGMSPSKTKKRKMKIKDALKVMLDEEAAKLVNPEELKQQAIEAVEQHGIVFIDEIDKICKKGEHSGGDVSREGVQRDLLPIIEGSTVNTKHGMVKTDHILFICSGAFQVARPSDLLPELQGRLPIRVELKSLTKEDFERILTEPNASLTLQYRELMKTEGVEIEFTKDGISRIAESAFRVNEKTENIGARRLHTVLERLMDGISFDASERRGEKIIIDENYVSEALNDVVENEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP83_ECOLX
Sequence: MEQNLPSRITKLIKKSESGDFASSYQLYKVFGSKEYGVEPDEKMSDYFKELSAKQLEGGQLRVADIHLENYKGFESLIMDFSMKKNSTILVGNNGCGKSTILDAIQKGLTHLSSRLSTRSHNGDGIEKHELRKGQNYASIAINYDYMGIRFPMIIATTEPGYEDRAKSNYSGINELGSIFKTAHSINPNVSFPLIAMYTVERANDVSTRDIENSEEIKEAQIWDKFKAYNKSLTGKADFKLFFRWFKELIEIENSDNADITALRAEIRAKEKDLDNPLLKALLAENKNSETTKKLLEDHQNSLKVLKEKLNSYYSVNSKTLHTVEDAMYSFLPGFSNLKLQRAPLDLIVDKNNVSLSVLQLSQGEKTILALIADIARRLTLLNPNSVNPLDGTGIVLIDEIDLHLHPSWQQNIIPRLEKTFKNIQFIVTTHSPQVCHTIDSQNIWLLKNGQKFKAPKGVRGAISSWVLENLFEVAQRPPEDKYTKLLQEYKNLVFSEKYASEDARKLGATLSQHFGPDDETLVELKLEIEKRIWEDDFEKDQ
What is the function of this protein?
Probable ATPase component of antiviral defense system retron Ec83, composed of a non-coding RNA (ncRNA), a reverse transcriptase (RT), this protein and a putative HNH endonuclease.  Expression of retron Ec83 confers protection against bacteriophage T2, T4 and T6.  At multiplicity of infection (MOI) of 0. 02 cultures slow growth when infected with T4 but do not collapse, at MOI 2 cultures enter growth stasis.
What are the official names of this protein?
Retron Ec83 probable ATPase.
Protein: SYK1_ECOLI
Sequence: MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDHTSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIKKYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAGDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSN_METC4
Sequence: MTIHQSPEAFGYDAFLRQHQNKEVLRFITCGSVDDGKSTLIGRLLHDTKQIFDDQVTALQRDSRKHGTQGGEVDFALLVDGLQAEREQGITIDVAYRFFSTDRRSFIVADTPGHEQYTRNMATGASTADLAVILVDARHGLTRQSRRHALLVSLLGIRRVALAINKMDLVGWSQDKFEAIVSGFQAFAAPLNFTEVRAIPLSAKNGDNVVLPGTAATWYTDVPLLRYLEEVPVKSEERAAAFRMPVQWVNRPNSDFRGFSGLIASGSVAPGDAVTVAPSGKTSTIARIFTADGDLERASEGQSVTLVLADEVDASRGAVIATSDAPLTLTDSLDVRLFWAAESDLVPGANLWAKVGTQTVNAVVKAVHRRIDPETGQAGPADKLAVNDIGDVTLTLDRQIAVDPYAENRDTGSLILIDRETTDTAALGLVQTIVASSKVAPAPTASVTASAEPARSGGLLAGLKRLFGG
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: HSCA_METFK
Sequence: MALLQISEPGQSTAPHQHRLAVGIDLGTTNSLVATVRSGLSTVLLDEAGKALLPSVVHYAANGQVEVGYAAQRQQSHDPQNTIASAKRFLGRGLNDIGDTSHLPYQFVDVPGMVQIETRAGIKSPVEISAEILKSLKARAEQALGGELTGAVITVPAYFDDAQRQATKDAARIAGINVLRLLNEPTAAAIAYGLDNASEGIYVVYDLGGGTFDVSILRLTKGVFEVLSTNGDSALGGDDFDRRIFHWILEQTHLQAPNPADTRLLMTASKEAKEWLTEHTSANIAVTLSNGKTVDLSLSRTEFHSLTQPLLNRTLVPIRKALRDASLTVKEVKGIVLVGGATRMPQVQQAVADFFGQAPLTNLDPDQVVALGAAIQANILAGNRHDDELLLLDVIPLSLGLETMGGLVEKIIPRNSTLPIARAQDFTTFKDGQTAMSIHVLQGEREMVADCRSLGRFELRGIPPMAAGAARIRVTFQVDADGLLSVSAQEQTSGAHANIVVKPSYGLSEEQITNMLQASFTAAEADKHARALQEARVDAARLLEALEAALRQDGDKLLNDEERTEITRQMEHLRNIAQHEDSDAINKAVDALNHATETFAARRMDASVKQALAGQSLNTLDI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GFA_PARDP
Sequence: MVDTSGVKIHPAVDNGIKPAQPGFAGGTLHCKCSTNPVRVAVRAQTAHNHVCGCTKCWKPEGAIFSQVAVVGRDALEVLEGAEKLEIVNAEAPIQRHRCRDCGVHMYGRIENRDHPFYGLDFVHTELSDEDGWSAPEFAAFVSSIIESGVDPSRMEAIRARLRELGLEPYDALSPPLMDAIATHIAKRSGALAA
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: CYB_TUPGL
Sequence: MTNMRKKHPLLKIINHSFIDLPAPSNISSWWNFGSLLGMCLVLQIITGLFLAMHYTADTTTAFSSVTHICRDVNYGWVIRYLHANGASMFFMCLFLHVGRGLYYGSYLYLETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPLGIISDADKIPFHPYYTIKDILGVVALLTVLSSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILMFVPFLHTSKQRSMTFRPISQCLFWILVADLITLTWIGGQPVEHPFIIIGQVASILYFTIIIILMPLAGWLENYLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.