PharMolix/UniProtQA huggingface dataset:
Protein: KCY_STAAS
Sequence: MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQIK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEB_ECOHS
Sequence: MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIHAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGEPEVKVEPAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEKLRIWQAPPQVTEPVHRLAGMLHKYQHALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPN50_TREPA
Sequence: MCMMGSVFSRKGMLCVLAVWCAASAAYPLRLRYKFRKGDTHRINSLIREDVFVNDTLAHTAEITNRITVHVSEVRVAHGSAPDAARYVCHFMTSEKSPNNTFRWGRHYESIFWRDAFGVYDIDRSFFMPVVRNVPVFPDYDIEVGDTWEHEAEEAHDLRDGFGIQTPFIVPFTVSYTYRGEVQRGSRRYHHITAAYSMSYESPKRTHGVQRNAKEGMYPVRTTGVSKQNLYWDNELGNIAEYDDEFRILLYLSGGTVLRYQGTATAKNFAPERFDPARTVVELQETLKDLHMPDAKVRETEEGVTISIENVQFDADSASLAPSEYEKLRKIAELLRAFPDRELLVSGHAARRGSVQDQQRISEERADVVARYLQELGVVDAAHVYTRGCGAQQSIAPNDSEDGRRKNRRVEITIISK
What is the function of this protein?
Could function as a porin.
What are the official names of this protein?
Outer membrane protein Tpn50, Antigen Tpp57.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: GLPK_TRIV2
Sequence: MQTSSSGYILALDLGTTGNRAFIFNNAGKIVAQAYKELTQHYPQPGWLEHDAEEIWQDTCWVMKTAIANAQISPSEIAAIGLTVQRETCLLWDKTTGKPLHKAIVWQDRRTAPLCHQLQEKGYAQEIYSRTGLVVDAYFSATKLRWLLDYITGVDLKNVLAGTIDTWILWKLTGGKVHATDHSNASRTMLMNLKTGEWDEQLLEILQIPAHILPQIQPSLGKFGLTDTSLLDTAIPITAILGDQQAALFGHGCDRPGLMKCTYGTGSFLVAHTGSNIVRSQHQLISTIAWTQYNSQENINIGYALEGSMFTSGACIQWLRDGIKLIKTAAETETMANQVDDNGGVYFVPAFSGLGAPYWDMNARGAFFGITASVQPQHLVRAVLEAIAYQVLEVVQAINASCSSPMQRLIVDGGACENNFLMQFQADVLGIPVERPTMRDTTVQGAAFAAGLAVGFWDSYTALVNQRQIDRIFEPGEGSQNAIYNFATWQKAVKRSLDWV
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: TF2B_METM6
Sequence: MKVEAITKEETKKPERKIKLAIAKPEDYSNKNVILEKEEELICPVCGSKNIIKDYERAEIVCEMCGCVLQQNLFDVGPEWRAFDHEQRVKRSRVGAPMTYTIHDKGLSTVIDWRNKDSYGKDISADKRAQLYRLRKWQRRIRVSDASERNLAFALSELDRIASKLGLPRNVRENAAVLYRGAVEKGLIRGRSIEGVAAAALYAACRRCKVPRTLDEIAEVSRVDRKEIGRTYRFISRELNIRLAPTNPVDYVPRFASELKLPGEVESKAISILQKAGEKGLTSGRGPTGVAAAAIYIASVLQGTRRTQREVADVAGVTEVTIRNRYKELTEHLDIDVTL
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: CIPKG_ORYSJ
Sequence: MARRAREEEADQVERKLVLGRYELGRLLGQGTFAKVYYGRDLRSGESVAIKVIDKARLRRTEGMVEQLRREISIMRMVRHPNVVGIREVLASRARVFVVMEYARGGELFAKVARGRLTEEHARRYFQQLVAAVGFCHGRGVAHRDLKPENLLLDEEGRLKVTDFGLAALPEQLRQDGLLHTQCGTPAYVAPEVLRKRGYDGARADLWSCGVVLYVLLCGFLPFQHENYAKMYQKIFKAEYQVPPWVSGDARRLIVRLLVVDPAKRISIPEIMRTPWFKKGFVPPVPTSPVSPKKWEEDDVLLDGGDSGAMSPRTCNAFQLISSMSSGFDLSGMFESEQKAATVFTSRAPAATVIQKLEAVGRSLGYSATRGKGWKLRLEATADGANGRLAVTVEALEVAADVAVVEFAHDAGDELEFNKFCAVDVRPGLADIVWAWQGDRPAAPDVAAATVECSPA
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting protein kinase 16, OsCIPK16.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: RSMG_NITEU
Sequence: MNLEKQLHDGLKAIPELSADTGHLCSRLLRYIELIAKWNSTHNLTSVRNPESMITRHMLDSLVILPHVSGPGIVDVGSGAGFPGIPVALARPEWQVTLVESNQKKAAFLLQAVLELGLPNISVKQGRVEKIKLENKVDTVVSRAFSSLERFMSLSKHLSENDSDHCRFIAMKGEFPDMELMQLSSEFVVEKIVAVTVPGLKAKRHLVVIRYQPG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_MYCTO
Sequence: MTSDVTVGPAPGQYQLSHLRLLEAEAIHVIREVAAEFERPVLLFSGGKDSIVMLHLALKAFRPGRLPFPVMHVDTGHNFDEVIATRDELVAAAGVRLVVASVQDDIDAGRVVETIPSRNPIQTVTLLRAIRENQFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPELWNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEQVRLPSIYFAHRRKVFQRDGMLLAVHRHMQPRADEPVFEATVRFRTVGDVTCTGCVESSASTVAEVIAETAVARLTERGATRADDRISEAGMEDRKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: ZN496_MOUSE
Sequence: MPTALCPRVLAPKESEEPRKMRSPPGENPSPQGEPPSPESSRRLFRRFRYQEAAGPREALQRLWELCRGWLRLERHTKEQILELLVLEQFLAILPWEIQSWVRAQEPESGEQAVAAVEALEREPGRPWQWLKHCEDPVVIDDGDGPAAPQDLEQERMSAESQSYPDAPPGALVQGTGLLSRSPGQPSEDLVPQDAFVVQEQSIRDAQPVATCQLPPNRVSPFKDMILCFSEEDWSLLDPAQTGFYGEFIIGEDYAVSMPPNEPPVQPGHSHEEENGLRVTEWTTDLQDKEIPQASCLDLSSLQPFQGEERRKWEELQVPELQPCPQVVLSQSPCPAGGDPPALKSSLDQEVTIEIVLSSSGDEDSQHSPYCTEELRSPPEDLHSVPAHQSNASAEGEVQTSQKSYVCPNCGKIFRWRVNFIRHLRSRREQKPHKCSVCGELFSDSEDLDGHLETHEAQKPYRCTACGKSFRLNSHLISHRRIHLQPASQQPMKKSEEEALETEGTGASDLLEKSKAKLSFQCGDCEKSFQRHDHLVRHRRHCHLKDETRPFQCRYCVKTFRQNYDLLRHERLHMKRRSKQALNSY
What is the function of this protein?
DNA-binding transcription factor that can both act as an activator and a repressor.
What are the official names of this protein?
Zinc finger protein 496, NSD1-interacting zinc finger protein 1, Zinc finger protein with KRAB and SCAN domains 17.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYR_LISIN
Sequence: MNVMQENQIKLIEHIKQAVVQAVGLEETEVPEILLEVPKDKKHGDYSTNIAMQLARVAKKAPRQIAESIVPELKKDTKLIKEVEIAGPGFINFYLDNAYLTDLVPVILTEDKKYGESDFGKGEKFQIEFVSANPTGDLHLGHARGAAIGDSLANIMKMAGFDVSREYYINDAGNQINNLVLSAEARYFEALGLESEFPEDGYRGSDIIALGKDLAAKYGDKYVNASEEERRSVFRVDALAFETGKLRADLEEFRVSFDEWFSETSLYEENKVLPALERLRENGYIYEQDGATWLRTTDFEDDKDRVLIKSDGSYTYFLPDIAYHLNKLERGFDVLIDIWGADHHGYIPRMRAAIEALGYSPNQLEVEIIQLVHLFEDGVQVKMSKRTGKSVTMRDLIEEVGLDATRYFFAMRSSDTHMNFDMSLAKSTSNDNPVYYVQYAHARISSILRSGKEQGLEVSKDANMSLLETEAEYDLLKVLGEFADVVAEAAVKRAPHRIVRYLNDLATAFHRFYNSNKVLDMDNLEVTKARLALIKTAQITLRNGLTLLGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_COXBR
Sequence: MLQPSNRKYRKDFKGRNRGIASRGNRVSFGEFGLKATECARITARQLEAARRTIARHIKRGGKITIRIFPDKPITKKPLEVRQGKGKGSVEYWVALVQPGRMIFEIEGVDEALAREAFSRAAAKLPLKCLFVKRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL10_FERNB
Sequence: MLRRPEKEQLVQELTSEFQNSSLVLFTDFKGLTVAQMTNLRRALREKLGSGARLTVVKNTLLKMALKNSGYDVDSHESSFFGPTAVLYVTEGDPVEAIKVFYNFVKENKGTPVCKGLFLERKFFAGEQLEDLSKLPSRDQLIAMVVGGIQAPIRGLVNSLAGVLRSVLYALNAIKEQKEKQ
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL17_CORU7
Sequence: MPTPKKGARLGGSASHQKKILSNLAAQLFENGAIKTTDAKAKLLRPYAEKIITKAKNGTLADRRNVLKLIPNKDVVSHLFTELAPKFEGREGGYTRIIKLENRKGDNAPMSQISLVTEELASKEAERATRAAASKKAAEEKAAEAAEEKDEAAEEK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: NOC_BACCR
Sequence: MKNTFSRLFGFGDKESEFELQDESHEEIDKKVYEEIQEIPIVNITPNRYQPRTVFDDARIDELALTIRTHGLIQPIVVRQYEDDKYEIIAGERRFRAATKLGWEKVPAIIKNLNDTETASVALIENLQREELTAIEEAVAYQKLIELHNLTQEALAQRLGKGQSTIANKLRLLKLPEEIKSALLEKSITERHARALIPLKNEELQLKVLQEIVEKQLNVKQTEERIAKLLEEAKPKRKAKQKAVSRDTRIAMNTIRQSLQMVTESGLNVNSEEEEFDEYYQITIKIPKKK
What is the function of this protein?
Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle.  It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
What are the official names of this protein?
Nucleoid occlusion protein, Noc.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SPHX_SYNY3
Sequence: MFDLSRLSRGIVPMALLLLGISACTPSQTSQSIAINGSSTVYPITEAIVADFSGGKKGVDIDVEFSGTGGGFKLFCEGKTDIADASRPINKQEMKLCNDNQVRYVELPIAFDAITVVSNPKNDWLKSLTVEELKRIWEPAAEKTLTRWNQVRPEFPDQPINLYSPGEDSGTFDYFTEAIVGQAGASRLDTLKSEDDEILVQGVVQDLYSLGYFGFAYYEGRIADLKAIGVDNGRGPVLPSRETVEKSEYQPLSRPLFIYVNATKAQDNPALREFVDFYLANASATATKVGYIPLPEEAYNLGKISFNKGEVGTVFGGESVMDLTIGELLKKQASFE
What is the function of this protein?
May be involved in the system for phosphate transport across the cytoplasmic membrane.
What are the official names of this protein?
Protein SphX.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
Protein: RIR1_EBVG
Sequence: MATTNHVEHELLSKLIDELKVKANADPEADVLAGRLLHRLKAESVTHTVAEYLEVFSDKFYDEEFFQMHRDELETRVSAFAQSPAYERIVSSGYLSALRYYDTYLYVGRSGKQESVQHFYMRLAGFCASTTCLYAGLRAALQRARPEIESDMEVFDYYFEHLTSQTVCCSTPFMRFAGVENSTLASCILTTPDLSSEWDVTQALYRHLGRYLFQRAGVGVGVTGAGQDGKHISLLMRMINSHVEYHNYGCKRPVSVAAYMEPWHSQIFKFLETKLPENHERCPGIFTGLFVPELFFKLFRDTPWSDWYLFDPKDAGDLERLYGEEFEREYYRLVTAGKFCGRVSIKSLMFSIVNCAVKAGSPFILLKEACNAHFWRDLQGEAMNAANLCAEVLQPSRKSVATCNLANICLPRCLVNAPLAVRAQRADTQGDELLLALPRLSVTLPGEGAIGDGFSLARLRDATQCATFVVACSILQGSPTYDSRDMASMGLGVQGLADVFADLGWQYTDPPSRSLNKEIFEHMYFTALCTSSLIGLHTRKIFPGFKQSKYAGGWFHWHDWAGTDLSIPREIWSRLSERIVRDGLFNSQFIALMPTSGCAQVTGCSDAFYPFYANASTKVTNKEEALRPNRSFWRHVRLDDREALNLVGGRVSCLPEALRQRYLRFQTAFDYNQEDLIQMSRDRAPFVDQSQSHSLFLREEDAARASTLANLLVRSYELGLKTIMYYCRIEKAADLGVMECKASAALSVPREEQNERSPAEQMLPRPMEPAQVTGPVDIMSKGPGEGPGGWCVPGGLEVCYKYRQLFSEDDLLETDGFTERACESCQ
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, R1, Ribonucleotide reductase large subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: ZN271_PONAB
Sequence: MEIQFNYESQEHHLLSDGENKTKIGKPASEEGITAKIEPLTEESSSLRENVLQDSEGREFCEFGDKLNEKDQNVFKRRPHNCDEYGQSFVWNTGLFRHRKTHCEKPYECDKCGKAFSVSSALVLHQRIHTGEKPYSCNWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLIIHQRIHTGEKPYQCSHCSKSFSQRSDLVKHQRIHTGEKPYTCNQCNKHFSQSSDVIKHQRIHTGEKPYKCDVCAKAFSQSSDLILHQRIHTGEKPYPCNQCSKSFSQNSDLIKHRRIHTGEKPYKCNECGKAFNQSSVLILHQRIHTGEKPYPCDQCSKTFSRLSDLINHQRIHTGEKPYPCNQCNKMFSRRSDLVKHHRIHTGEKPYECDECGKTFSQSSNLILHQRIHTGEKPYPCSDCTKSFSRRSDLVKHQRIHTGEKPYACNQCDKSFSQSSDLTKHQRVHSGEKPYHCNSCEKAFSQSSDLILHQRIHTGEKPYLCTQCSKSFSQNSDLIKHQRIHTGEKPYKCSECRKAFSQCSALTLHQRIHTGEKPNPCNECGKSFSRHSDLINHQKIHTGEKPYKCDACGKAFSTCTDLIEHQKIHAGEKPYRCVQCSRSFSQLSELTIHEEVHCGEDSQNVMNVRKPLVYTSTLFSTRDTVPGKNLMNAVDY
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 271.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABR_SHIFL
Sequence: MGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPHG_MYCTU
Sequence: MAELTETSPETPETTEAIRAVEAFLNALQNEDFDTVDAALGDDLVYENVGFSRIRGGRRTATLLRRMQGRVGFEVKIHRIGADGAAVLTERTDALIIGPLRVQFWVCGVFEVDDGRITLWRDYFDVYDMFKGLLRGLVALVVPSLKATL
What is the function of this protein?
Epoxide hydrolase capable of hydrolyzing long or bulky lipophilic epoxides such as 9,10-epoxystearic acid and cholesterol 5,6-oxide in vitro.  The physiological substrates have yet to be identified, but could be fatty acid or steroid derivatives.
What are the official names of this protein?
Epoxide hydrolase EphG, EH, Cholesterol-5,6-oxide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the limonene-1,2-epoxide hydrolase family.
Protein: SYT_NATTJ
Sequence: MLKITLKDGSVKEIEKGSNVLDLAKSISNRLAKEAVGAKVDGKTVGLNKELNENCEVEILSFEDDEGCDIYRHTSSHILAHAVKRLYDNVKLGIGPPIKDGFYYDFDLEHSLSDKDLEDIKKEMKKIIKEDLPIERKVYKRDEAIEMFKEMGEDYKIELIQDLGEDEEICCYQQGDFIDLCQGPHLPSTGKIKDTALDLLKVAGAYWRGDENRAMLQRIYGTSFIKKSQLEEYIQRLEEAKKREHRKLGKELDLFSFHEEAPGSPFFHNNGMIVINELIDFWRREHRKAGYQEISTPIILNRGLWERSGHWDHFQENMYFTEIDDEDFAVKPMNCPGAMLVYNNNMYSYRDFPLRVAELGKVHRHELSGALHGLLRARSFTQDDAHIFMLPSQVEEELENVINLVDRFYSVFGFNYYVELSTKPEKAMGSDEIWDRAINALKSVLEKRGIKYIVNEGDGAFYGPKIDFQLEDAIGRSWQCSTIQLDFLLPERFDLTYIGEDGQKHRPVMIHRVIYGAIERFFALLIEHYEGKFPLWLAPRQAVIIPIADRHMEYGKDITKQLESEGIRADLDQRNEKIGYKIRDAQLKKVPYMLIVGDDEVENKTVSVRTREDGDIGSKSVAELVDEIKVEIDDMD
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_GLUDA
Sequence: MAKKIVGYIKLQIPAGKANPSPPVGPALGQRGLNIMQFCKEFNAKTQGLEPGMPIPVVITAFADRTFTFITKTPPNTYFLMKAANIKKGSSTVGKAAAVGSVTMAQLREIAEQKKQDMNANDVDGAVRMLIGSARSMGLTVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: YMIA_RHIRD
Sequence: MGFPISAAAIALRACSAAVPRGRAISQAMPWASQ
What are the official names of this protein?
Uncharacterized protein in miaA 5'region, ORF1.
Protein: FGF13_HUMAN
Sequence: MAAAIASSLIRQKRQAREREKSNACKCVSSPSKGKTSCDKNKLNVFSRVKLFGSKKRRRRRPEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
What is the function of this protein?
Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity).  Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity).  Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity).  Regulates voltage-gated sodium channels transport and function (PubMed:15282281, PubMed:33245860).  May also play a role in MAPK signaling (By similarity).  Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity).
What are the official names of this protein?
Fibroblast growth factor 13, FGF-13, Fibroblast growth factor homologous factor 2, FHF-2.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 5]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: Cell projection, filopodium. Cell projection, growth cone. Cell projection, dendrite. Cell membrane, sarcolemma. Cytoplasm. Note=Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes.
Protein: NADK_ECOLU
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIAHELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLAIL_XENTR
Sequence: MVVPGNSPGIPRDHAIDISDRAMDLEAEPDHSSDLKEVQKLHELVKRLEIQNQQLKIKRNPQSSNIQNISGIDNQLSALNCSGVMNSINIQPEKGDLQKMPNLQSQLEQISSEKENIPALGMDAQMQYEKVCSDSKPGSKVEINCDQDDCCFYSVDGSGRSDLEEAISKMSELNSSGENILDETALDEVDVLELGSCSEDEEDCWLYVSPRKVENAEQKLDSPLKWCRQVLDHHSPETEAACRSLIGKLDQASRWKSLYCSPLASPSAYNTNAECSYGSNTLNSPGCLKSTNKALLTCGSSGYLSFHSALSSQSSVDSELSTSDDSISMGYKLQDLTDVQVMARLQEESLRQDYASSSASVSRRSSSASLHSLRRGTFSDQEFDTYSLEDEDDCDCSLSFRSSHRYSPSPLSSPRCQSPSAAESRATTSRIRPPRRSIQNHVQERMKYANCEDELRHSMPNLAKTSLRSLEAVRSSRSLESDLQGPSSRLTRMQQPSTSTPPSKVRYGASNQPALTVRQPGKPGVSTSSLMTSRQPVKSSGYNNSSGLRKIQSSPGLNPSGSGAVSRTGNASSSIKHSTVKSQASMGSTVPKSKMIQPSRRSLSSAKMNSTLDDDSWKDGCY
What are the official names of this protein?
SLAIN motif-containing protein-like.
What is the protein family that this protein belongs to?
Belongs to the SLAIN motif-containing family.
Protein: NECA2_RAT
Sequence: MCERAARLCRAGAHRLLREPPPQGRALGGLLRWVGARMGEPRAPLVPDIPAADPDPGPAAPRGGTAVILDIFRRADKNDDGKLSLEEFQLFFADGVLNEKELEGLFHTIDSDNTNHVDTKELCDYFVEHMGDYEDVLASLETLNHSVLKAMGYTKKVYEGGNNVDQFVTRFLLKETANQIQSLLSSVESAVEAIEEQTSQIRQDHCKPSPGVNESRYGGPTPPYIPNHKLVVPEPVKSLPVAIGEPKEEGLEVQISRLAELIGRLESKTLSFDLQQRLSDEEGTNMYLQLVRQEMAVCPEQLGEFLDSLRQYLRSTAEERNCFHVAAVRMADGLTFVIYEFWETEEEWKRHLQSPVCKAFRHVKVDTLSQPEALSQISVPAAWCTSGRD
What is the function of this protein?
May act as a signaling scaffold protein that senses intracellular calcium.  Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation.
What are the official names of this protein?
N-terminal EF-hand calcium-binding protein 2, EF-hand calcium-binding protein 2, Neuronal calcium-binding protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Cell projection, axon. Cell membrane. Note=Colocalizes with ADORA2A and/or mGluR5/GRM5 at the plasma membrane (By similarity). Found in neuronal somata (PubMed:26843217). Detected in the cytoplasm of striatal neurons, at postsynaptic sites, filling dendritic shafts and spines, and at presynaptic sites, filling axon terminals (PubMed:17689978).
Protein: HSDB_SESIN
Sequence: MDLINSLLNFVVPPASLLMLAFTWPTLFFITTCEWLYNTYLNSENMENKVVLITGASSGIGEQIAYQYAKRGANLVLVARREHRLRGISENARRLGAPNVLIMAADVVKEEECRRFINETINYYGRVDHLVNTVSLGHTFYFEEASDSSVFPILMDINFWGNVYPTYVALPYLRESNGRIIVNASVENWLPLPRMSLYSAAKSALINFYETLRFEVKNEVGITVATHGWIGTEMTRGKFMVEEGAEMQWKEEREVHVTGGPVEEFAKQIVSGACRGDPYVKYPSWYDIFFLYRVFAPKVLDWTFRFLLTNGGARRTSFIGTGRPLLETSSPRRSAVMEGSSPRRLPPGPLTFSPAFQQQKSE
What is the function of this protein?
Has dehydrogenase activity against corticosterone (11 beta-hydroxysteroid) and estradiol (17 beta-hydroxysteroid), with similar activities to both sterols in the presence of NADP(+), but negligible activity to either sterol in the presence of NAD(+).  May be involved in signal transduction regulated by various sterols.
What are the official names of this protein?
11-beta-hydroxysteroid dehydrogenase B, 17-beta-hydroxysteroid dehydrogenase B, Seed oil body protein 3, Steroleosin-B.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Single-pass type II membrane protein. Note=Surface of oil bodies. Exists at a monolayer lipid/water interface.