PharMolix/UniProtQA huggingface dataset:
Protein: MTFA_SERP5
Sequence: MIKWPWKTHQPQAETLAQWQDALAIPLLSPLDEREQQRLIVVAGQILQQKSIVPLQGLVLTSQMQARIALLFALPVLELGAECLDGFNEILLYPSPFVVEDEWQDDFGLVHSGPVVQSGQSWEQGPIVLNWQDVQDSFDLSGFNLVIHEAVHKLDMRNGGSATGIPPIPLRDIAAWEHDLHAAMENLQDEIDMVGEEAASMDAYAATDPAECFAVLSEYFFSAPELLANRFPVMYQHFSRFYKQDPLARLQRLQAENSAEVP
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_MYCTA
Sequence: MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVEFFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRYAAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISVQLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGTDGQDQTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAPLADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATY_ECOHS
Sequence: MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: COX1_BOSIN
Sequence: MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: OBG_XANCB
Sequence: MKLVDEAEILVTAGNGGNGCVGFRREKFIPLGGPDGGDGGNGGSVWIVADENVNTLVDFRHERAFKAQRGENGMGRQAYGKGGEDRVIVVPVGTVVMNVQTDEIIGDMTQHGDRLLVAKGGKGGLGNMHFKSSVNRAPRQSTTGEEGEERLLKLELKLLADVGLLGFPNAGKSTLIRAVSAATPKVADYPFTTLYPNLGVVSVEAYRSFVIADVPGLIEGAADGAGLGTQFLRHLQRTRLLLHLVDISPMDGGVDGVSPVDQVRTIERELERHDPALLEKPRWLVLNKADLMFPEEAQAAAEAIVAELGWTAPWYLVSALGRDGTFPIMKDVMAFFDRQREDELEARNAG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGAL_ECOL6
Sequence: MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPDADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPAENPTGCYSLTFNIDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFQVTTLFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPELWSAEIPNLYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGEMRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQYFQFRLSGRTIEVTSEYLFRHSDNEFLHWMVALDGKPLASGEVPLDVGPQGKQLIELPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPSASHAIPQLTTSGTDFCIELGNKRWQFNRQSGFLSQMWIGDEKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGHGEMVINVDVAVASDTPHPARIGLTCQLAQVSERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: MT_OREMO
Sequence: MDPCECAKTGTCNCGGSCSCTKCSCKSCKKSCCDCCPSGCSKCASGCVCKGKTCDTSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: METK_METFK
Sequence: MSEYLFTSESVSEGHPDKVADQISDSILDAILEQDPTARVAAETLTNTGLVVLAGEITTTANVDYIKIARDTIKRIGYDNADYGIDYKSCAVLVAYDKQSPDIAQGVNNANDDPLDQGAGDQGLMFGYACDETPQLLPLPIWLSHRMVERQSQLRKDGRLPWLRPDAKSQVTIQYMDGKPHKIDTVLISTQHAPDISLDQVRESVIEEIIKPTLPQELIKGDIKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRCLVQVSYAIGVAKPTSVMVETYGTGKVSNEILTQLVLDHFDLRPKGIVKMLDLLRPIYAKTAAYGHFGRDEPEFTWEATDKAALLRAAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEMG2_COLGU
Sequence: MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLSSGSSRFPHRQRSQHYSGQKDKQHTESKGSSSIQHTYHVDANDHDQTQKSQQYDLNAQHKTTKSEQHLGRSQRLLNYKQKGRDHVKPKRHFRLIVIHRKGGQVHHGTQNPSQNQGNSPSGKGISSQYSNTEERLRVCGLSKEQASASGAQKGRTQGGSQSSYVLQTEELVANKQQRETQNSHRNKGHYQNVVEVREGHSSKLQTSLHPAHQHRLQHGSKDIFTTQDELLVYNKNQHQTKNLNQDQEHGRKAHKVSYQSSSTEERQFNHGEKSVQKDVPKGSISIQTEEKIYGKSQNQVSIPSQDQEHGHKENKISYQSSSTEERRLNCGEKDIQKGVSKGGISIQTEEQIHGEFQNQVTISNQDQEHGHKENKISYQSSSTEERRLNGGEKDIQKSVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGHKENKISYQSSSTEERQLNYGGKSIQKDVSQSSLSFQTEKLVEGKSQIQTPNPNQDQWSGLNAKGNSGKSADREQDLLSHEQESRYQQKSSGAHNTVNIEHEVAYDDLLTQQYNEDRNPIST
What is the function of this protein?
Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa.
What are the official names of this protein?
Semenogelin-2, Semenogelin II, SGII.
What is the protein family that this protein belongs to?
Belongs to the semenogelin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FEOC_SHIFL
Sequence: MASLIQVRDLLALRGRMEATQISQTLNTPQPMINAMLQQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: IR11_HCMVA
Sequence: MQTYSTPLTLVIVTSLFLFTTQGSSSNAVEPTKKPLKLANYRATCEDRTRTLVTRLNTSHHSVVWQRYDIYSRYMRRMPPLCIITDAYKETTRQGGAAFACTRQNLTLYNLTVKDTGVYLLQDQYTGDVEAFYLIIHPRSFCRALETRRCFYPGPGRVVVTDSQEADRAIISDLKRQWSGLSLHCAWVSGMMIFVGALVICFLRSQRIGEQDAEHLRTDLDTEPLLLTVDGDLQ
What are the official names of this protein?
Viral Fc-gamma receptor-like protein IR11, gp34.
What is the protein family that this protein belongs to?
Belongs to the RL11 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TRPF_ACIF2
Sequence: MPMVRIKICGITNTEDARAAAAAGADAVGLVFYRSSPRALDAVRARKILAALPPFVTRVGLFVNAEAADVAATLQQCPLDVLQFHGDESPSLCRGFGRPYIKVLRVTAAQDLRPAVDAYHDAQGLLLDCAAPGVWGGSGRSFDWWRLPDLGKPLILAGGLHAENVAEAIAIARPYAVDVSSGVELSPGRKDHDKMARFVARVRGT
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: IF1_CORDI
Sequence: MAKEGAIEVEGRIIEPLPNAMFRVELDNGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLTRGRIVYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YICR_ECO27
Sequence: MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAIKINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: Y1749_STRPZ
Sequence: MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVLLVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN
What are the official names of this protein?
UPF0473 protein Spy49_1749c.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: ISPD_ECO24
Sequence: MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RUVB_LACP3
Sequence: MADADKDRLVSGDVDDSNEAQIEKSLRPRMLAQYIGQDRVKHQLEVYITAAKQREESLDHVLLYGPPGLGKTTLALVIANELGVNIRTTSGPAIEKPGDLVALLNELHPGDVLFIDEIHRLPKIVEEMLYSAMEDFYIDIVVGQGPTAHPVHFPLPPFTLIGATTRAGMLSAPLRDRFGISEHMAYYSADDLSEIVKRSATIFDMAIDAEGAHEIARRSRGTPRVANRLLKRIRDFAEVAGQSPVDIQMVDHALDQLQVDQQGLDQIDRKLLMFMIRDYEGGPVGLSTIAANIGEEMATIEEMYEPYLLQIGYLKRTPRGRMVTPAGFAHMGMSAEQH
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PNP_METRJ
Sequence: MFDVQREELMWGDRKLVLETGKVARQADGAVIATYGETSVLATVVAAKEPKPGIDFMPLTVNYQERAYAAGRIPGGYFKREGRPSEKETLVSRLIDRPIRPLFIEGWRNDTQVVVTVLTHDLENDPDIVAMVAASAALTLSGVPFMGPIGGARVGYINGGYRLNPLVTETKEESSLDLVVAGTQDAVLMVESEAKELSEDVMLGAVMFGHKHFQPVIEAIIRLAEKAAKEPRDFKAPENADVEKAVLEVCEAELRAAYTKTVKQERYAAVDAVKAKVMAALCPEGAEKFPAEKVKAAFKEAQSKVVRWNILDSGARIDGRDVKTVRSILSEVGVLPRAHGSALFTRGETQALVVATLGTGEDEQFIDALEGTYKERFLLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIRPVLPPAHEFPYTIRVVSEITESNGSSSMASVCGGSLSLMDAGVPLRRPVAGIAMGLILEGERFAVLSDILGDEDHLGDMDFKVAGTDEGVTSLQMDIKIAGITEEIMKIALAQAKDGRAHILAEMAKALTAARPELGEYAPRIETMQIPTDKIRDVIGTGGKVIREIVEKTGAKINIEDTGVVKIASADGKAIKAAYNWIRSIVAEPEVGVIYDGTIVKCMEFGAFVNFFGAKDGLVHISELAAQRVAKVQDVVKEGDKVKVKFLGQDDRGKIRLSMKVVDQQTGEDITDKIKAQRDAERAERGDEPREPREGGRHRGERRREAGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA_CRYNJ
Sequence: MSADKLPKALQATEDDIQLLLAAQCHLGTKNCDKSMENYVWKRRADGIHVINVGKTWEKLVLAARVLATIENPNDVCVISARPYGHRAVLKYGSFTGAQAIAGRFTPGSFTNYITRSFKEPRVIIVTDPRVDHQAIREAAYVNIPVIAFCDTDASTKFVDIAIPANNKSRHSIGLMWYLLCREVLRLRGTVPRGPTGPSGWDVLPDLFFYRDPEEIEREAAEKAAAAAAQEGADAEAAATSAAAGVTAEYDAGNAADAVLAAQPTETALDWSDEPVAGDWAAEPAADAQGGW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LBD11_ARATH
Sequence: MLKMEINGGVATPTASAVAKVTETTTPVNSPSPTSSPPPPPSPQQPPQPPVVLSPCAACKILRRRCADKCVLAPYFPPTDPAKFTIAHRVFGASNIIKFLQELPESQRTDAVNSMVYEAGARMRDPVYGCAGAIYHLQRQVSELQAQLAKTQVELVGMQLQRSSLLELIYNMEQTKLSVQEQGQQKMSFESSFESGDEFISSPDEESNDLGFLEDNNNNNNSSMSWWDPLWT
What are the official names of this protein?
LOB domain-containing protein 11, ASYMMETRIC LEAVES 2-like protein 7, AS2-like protein 7.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
Protein: IF3_BORPE
Sequence: MRLIGLDGEQLGIVKIADAFRLSEQSDVDLVEIAPNADPPVCRLMDYGKFKYQEQKRQAEARSKQKVIQVKEVKFRPATDEGDYQVKLRNLRRFLEEGDKAKVTLRFRGREMAHQELGMRVLERVRDDLIELAQVEAMPKLEGRQMVMVLAPRKKAVGKPDAAG
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_BRASO
Sequence: MLASTVTGALQEQGRAKVNLTLRVVGRRADGYHDLESVVAFADCADQLTLAPSPELTLTTTGPLADACGDTSDNLVLKAARLLAEAVPGLTLGAFTLEKVLPVAAGIGGGSADAAAALRLLARLNGLSLDDPRLQAVALKTGADVPVCVPSRACTMTGVGENLQPLALPVLPCVMINPRVPVATKDVFQALGLKPGDLLVGVSDVLAAPAWPKAGASIGDWVAALDQVKNDLEPPALKVQPIIGTVLDALRASNGVLLARMSGSGATCFAIYGGDADAKIAGAAIAAAHPEWWVHAGTLS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: HIS6_VESOH
Sequence: MSLAIRIIPCLDVCDGRVVKGTKFIDIKDAGDPVEVAKRYDLEGADEIIFLDITASIDGRDTMIHMVEAIAEQVFIPLTVGGGIRKAADVRAILNAGADKITINSAAIFNPNLINQLSKEFGSQCIVIAIDAKKIDYNKWGIFTHGGRKYTGIDAIEWAKKMTCGDNGAGEVLLTSMDCDGVKTGFDLLLTRAVSDAVDVPVIASGGVGNLEHLSEGVLQGAADAVLAASIFHFGEYTIQQAKKAMQENGIKVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_FRAP2
Sequence: MRIGIVAGELSGDQLGATLVEALKKKYPNAEIEGIGGPKMEAQGFKSLYPMDALSLIGFLEILSKGLSILNIRRKIIKYFKHNKPDIFIGIDAPDFNLTVEKKLRASGIKTIHYVSPKIWVWREYRIKKIRKATDKILAILPFEVEYYKNRHNFEAIYVGHPLAKNISLEIDRSKYKKRLGLENVELPILSVLPGSRTTEVTRLLPLFLDAIEKLQESGYKFKAIMPLAKPSLKPIFDQYNSQIRSLGIEVLETNSHDVLKASDLSLLASGTATLEAMLCKLPMVVGYKLSKLSAFIGRILIRGHSYWAFPNILHKSEIIKELIQEDCTVDNLFYELKRLFDDKQRNNYIVQEFKKIHEHMVVDTEEKIIEVLDSIIEKS
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: HAP28_RAT
Sequence: MPKGGRKGGHKGRVRQYTSPEEIDAQLQAEKQKANEEDEQEEGGDGASGDPKKEKKSLDSDESEDEDDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQSLSLNK
What are the official names of this protein?
28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PAP, PDGFA-associated protein 1, PAP1.
What is the protein family that this protein belongs to?
Belongs to the PDAP1 family.
Protein: RL29_HUMAN
Sequence: MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAMSARAEAIKALVKPKEVKPKIPKGVSRKLDRLAYIAHPKLGKRARARIAKGLRLCRPKAKAKAKAKDQTKAQAAAPASVPAQAPKRTQAPTKASE
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:32669547).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:32669547).
What are the official names of this protein?
60S ribosomal protein L29, Cell surface heparin-binding protein HIP, Large ribosomal subunit protein eL29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL29 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP2CN_RAT
Sequence: MELLGFTTLALVVSVTCLSLLSVWTKLRTRGRLPPGPTPLPIIGNLLQLNLKDIPASLSKLAKEYGPVYTLYFGTSPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDTHKGYGLIFSNGERWKVMRRFSLMTLRNFGMGKRSLEERVQEEARCLVEELQKTKAQPFDPTFILACAPCNVICSILFNDRFQYNDKTFLNLMDLLNKNFQQVNSVWCQMYNLWPTIIKYLPGKHIEFAKRIDDVKNFILEKVKEHQKSLDPANPRDYIDCFLSKIEEEKDNLKSEFHLENLAVCGSNLFTAGTETTSTTLRFGLLLLMKYPEVQAKVHEELDRVIGRHQPPSMKDKMKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRDYVIPKGTTVLPMLSSVMLDQKEFANPEKFDPGHFLDKNGCFKKTDYFVPFSLGKRACVGESLARMELFLFFTTLLQKFSLKTLVEPKDLDIKPITTGIINLPPPYKLCLVPR
What is the function of this protein?
A cytochrome P450 monooxygenase involved in polyunsaturated fatty acids (PUFAs) metabolism and signaling.  Catalyzes preferentially the epoxidation of double bonds of PUFAs.  Converts arachidonic acid (ARA, C20:4(n-6)) primarily to stereospecific products 8R,9S-, 11R,12S-, and 14S,15R-EET (PubMed:8246128, PubMed:14742258, PubMed:10491410).  Plays a major role in the formation of EETs and hydroxy-EETs (HEETs) in kidney (PubMed:10491410, PubMed:14742258).  Via EETs may inhibit the epithelial sodium channels (ENaCs) in nephron segments, preventing excessive sodium absorption during high dietary salt intake (By similarity).  Participates in the formation of anti-inflammatory hydroxyepoxyeicosatrienoic acids (HEETs) by converting 20-hydroxyeicosatetraenoic acid (20-HETE) to 20,8,9-HEET, an activator of PPARA (PubMed:14742258).  Metabolizes eicosapentaenoic acid (EPA, C20:5(n-3)) to epoxyeicosatetraenoic acid (EETeTr) regioisomers, 8,9-, 11,12-, 14,15-, and 17,18-EETeTr, preferentially producing 17R,18S enantiomer (PubMed:15766564).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:8246128).
What are the official names of this protein?
Cytochrome P450 2C23, Arachidonic acid epoxygenase, CYPIIC23.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Microsome membrane.