PharMolix/UniProtQA huggingface dataset:
Protein: SAMP1_HALVD
Sequence: MEWKLFADLAEVAGSRTVRVDVDGDATVGDALDALVGAHPALESRVFGDDGELYDHINVLRNGEAAALGEATAAGDELALFPPVSGG
What is the function of this protein?
Functions as a protein modifier covalently attached to lysine residues of substrate proteins, as well as a sulfur carrier in molybdenum cofactor (MoCo) biosynthesis.  The protein modification process is termed sampylation and involves the formation of an isopeptide bond between the SAMP1 C-terminal glycine carboxylate and the epsilon-amino group of lysine residues on target proteins.  May serve as a proteolytic signal in the cell to target proteins for degradation by proteasomes.
What are the official names of this protein?
Small archaeal modifier protein 1, SAMP1, Ubiquitin-like small archaeal modifier protein 1.
Protein: UXUA_SACD2
Sequence: MQETWRWFGPNDSISLQKIAQAGATGIVSSLHHVPTGALWQLEEIEAQKKIIEDAGLEWSVIESIPVHNDIKTRTGNFQEYIENYKQSVINAGKAGVKTICYNFMPVVDWTRTNLSYRLPNASQALRFEMTDFAAYDVYLLQRENAAADYSEEVLNRAKARFDAMDETEKDLLEKNIIAGLPGGEGSYTRDTIREAIQQFIDLGTEGFRNHMFEFLREIIPAAESVGVKMCIHPDDPPFSLFGLPRVVSTADDARKLLNAVPSPSNGLTLCAGSYGARGDNDLVGMAKEFGDRIYFVHLRNVKREPDGSFYEADHLDGDNDMVGLVNALLCEERRRHAAGETNCAIPMRPDHGHLMADELNLPDVKPGYSYTGRMKGLAELRGVIHALEVLQRQHAL
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: LIPA_MACCJ
Sequence: MATKNEEILRKPEWLKIKLNTNKSYTGLKKMMREHNLNTVCEEAKCPNIHECWGERKTATIMILGAICTRACRFCAVKTGLPNELDLNEPERVAESVRLMNLKHVVITAVARDDLKDGGAHVYAETIRKVREVNPYTTIEVLPSDMGGSIENWETLMAAKPDILNHNIETVRRLTPRVRARATYDRSLEVLRRSKELYPDIPTKSSLMVGLGETTEEIYEVMDDLRANDVDIMTIGQYLQPSRKHLKVQKYYTPLEFGKLRKVAMEKGFKHCQAGPMVRSSYHADEQVNEAAKEKHRLGELSSK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_BACCQ
Sequence: MATEKTYPMTQEGKQKLENELEDLKTVKRKEVVERIKIARSFGDLSENSEYDAAKDEQAFVEGRITQLENMIRNAVIITDNGEESTVVTLGKTVTFKELPDGDEEAYTIVGSAEADPFEGRISNDSPIAKSLLGKQIGEKVAIQTPGGEMQVEIISVK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: TAP46_TOBAC
Sequence: MGELSMQEMPLPALFEQGSKIHASAESSVDQDTVRKGCEILRQCEEMIGKLGLFSVNETKEDISTANLKYILVPYYLAELTEKVADNDRIKVLKASQAKLKEFISFCETMELVPEEEIETSTQGGANSSVDRRAKKIARFKRQRAAESKLLEIKERKERRGRSTKAAALSSPVETEEDDVLDDDGEEEREAWLTTISLGLCKAFDLLEMLKKEEEILSAVKEKQLQDGEREFSQAILDERTKKVETWHRDAAARAHHTKPAAPITCATFAQDVIEGRAKVSQAHEHKHQPLIFGPASLVGRNPTTEREKIAAQVFQPHYRLPTMSIEEAGLTEMNMMNEWQERNVKLMEEANSSWYKDTPKSRPGEDDEEDDDDAAQDKARAWDDWKDDNPRGAGNKKLTPCG
What is the function of this protein?
Involved in the regulation of the TOR signaling pathway.  Seems to act as a regulator of PP2A catalytic activity.
What are the official names of this protein?
PP2A regulatory subunit TAP46.
What is the protein family that this protein belongs to?
Belongs to the IGBP1/TAP42 family.
Protein: PYRDA_AQUAE
Sequence: MDLSVELFGIRFKNPVWVASGTFGYGVEAAEIYDISKLGAVVTKGLSLKERLGNETPRIVETPCGMLNSIGLQNPGVEKFLKEIYPKIKDVDTHFIANVFGETEEEYVEVCMALEDADKIVAYELNVSCPNVKKGGILFGHDPVILGNLVDRIKAKIKKPLLVKLSPNVTDVTEFAKVCIENGADGLVLINTLMGMKINIWKRKPDLATKTGGLSGPAILPIAVRMIYQVYEKFGDRIPIIGVGGITTWEDAMEHVMAGASAVQVGTANFYEPLAPLKVIEGIENFMKSQNIKDFKELIGIAHRVE
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Putative dihydroorotate dehydrogenase A (fumarate), DHOD A, DHODase A, DHOdehase A.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_METJA
Sequence: MKDKFGREIRSLRISITNKCNLQCFYCHREGHDSNNDRYMTPEEIGIIAKTSTKFGVKKIKISGGEPLLRKDVCEIIENIKDERIKDISLTTNGILLENLAEKLKDAGLNRVNVSLDTLNPELYKKITKFGDVERVINGIKKAIDVSLTPLKVNFLAMSINIKDLPDIMEFCRDIGAILQIIEFIPLKEELKGYYYNISPIENEIKEKADKVITRNFMQNRKKYIVDGLEIEFVRPMDNSEFCMHCTRIRLTYDGYLKPCLLRDDNLVDVLTPLRKGENLEPYFIECINRREPYFKIK
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: CALM3_MOUSE
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
What is the function of this protein?
Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding.  Calcium-binding is required for the activation of calmodulin.  Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases.  Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
What are the official names of this protein?
Calmodulin-3.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.
Protein: EXOS8_MOUSE
Sequence: MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRATTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPPVDAPDRGYVVPNVDLPPLCSSRFRTGPPGEEAQVTSQFIADVVDNSQVIKKEDLCISPGKLAWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVNLKKKSYLNVRTNPVATSFAVFDDTLLIVDPTGEEEHLSTGTLTVVTDEDGKLCCLHKPGGSGLTGAKLQDCMSRAVTRHKEVSKLLDEVIQSMRHK
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.  EXOSC8 binds to ARE-containing RNAs (By similarity).
What are the official names of this protein?
Exosome complex component RRP43, Exosome component 8, Ribosomal RNA-processing protein 43.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus.
Protein: DCLK3_HUMAN
Sequence: MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETPKSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHARGEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRTRSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAAKAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKEKKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
What are the official names of this protein?
Serine/threonine-protein kinase DCLK3, Doublecortin domain-containing protein 3C, Doublecortin-like and CAM kinase-like 3, Doublecortin-like kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CA14_CONSE
Sequence: IMYDCCSGSCSGYTGRC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like Sm1.4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLK_CITK8
Sequence: MTKYALVGDVGGTNARLALCDMTSGEISQAKTYSGLDYPSLEAVVRVYLDEHNARVEDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLRKEHLIQFGGAEPVAGKPIAVYGAGTGLGVAHLVHVDKRWISLPGEGGHVDFAPNSEEEGIILEELRAEIGHVSAERVLSGPGLVNLYRAIVKSDGRLPENLQPKDITERALADTCIDSRRALSLFCVIMGRFGGNLALTLGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFKAYVQDIPVYLIVHDNPGLLGSGAHLRQTLGQIL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WZYE_ECOL5
Sequence: MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADAPRRPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEC_PELTS
Sequence: MRSIVLLSGGLDSAVSLACSLQGGEVCLCLTFDYGQKAAEREKKAAAALAAHYKLRHRVIELPFLKEITSTALVSETSELPAAEEEELDENEASRSSAALVWVPNRNGVFINIAAAFAEAYRCDLVVTGFNREEAASFPDNSPEFVVAANASLSYSTLNKVRVASYTQGLNKTEIVKLGMNMGVPFDLIWSCYGGAEKMCRRCESCLRFIRAAKTAGLQLE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MRAY_CORGB
Sequence: MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAGIVVAYVFTNILAMIQGVGGFTVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKLVSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTIDLGFGGSVFGIIVFLIFIYVVVSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSVLCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEIASVAIQIGVFKTRGKRVFKMAPIHHHFEALGWAETTVAIRFWLIAIMAVLAGVGVFYSDWLHLAEV
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPIA_BLAGE
Sequence: MAHPRVFFDMSADGQPVGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSRFHRVIPNFMCQGGDFTNHNGTGGKSIYGTKFEDENFQLKHTGPGILWMANAGPNTNGSQFFITTAKTSWLDNRHVVFGSVVEGMDVVKKLESLGSQSGKTNKKIAVVDCGQI
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, PPIase, Cyclophilin, Cyclosporin A-binding protein, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCFP_SALEP
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLVSYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVVFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRHDEALDSQRSAQALHPYYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: LCHMO_ENTFA
Sequence: MKKSLLTIVLAFSFVLGGAALAPTVSEAHGYVASPGSRAFFGSSAGGNLNTNVGRAQWEPQSIEAPKNTFITGKLASAGVSGFEPLDEQTATRWHKTNITTGPLDITWNLTAQHRTASWDYYITKNGWNPNQPLDIKNFDKIASIDGKQEVPNKVVKQTINIPTDRKGYHVIYAVWGIGDTVNAFYQAIDVNIQ
What is the function of this protein?
Involved in chitin degradation.  Catalyzes the oxidative cleavage of glycosidic bonds in both alpha- and beta-chitin via a copper-dependent mechanism, leading to oxidized chitooligosaccharides with a dominance of even-numbered products.  Acts synergistically with the chitinase EfChi18A, and combining the two enzymes leads to rapid and complete depolymerization of crystalline chitin, especially with beta-chitin as a substrate.  Is likely involved in a chitin degradation pathway that allows E. faecalis V583 to grow on chitin as a carbon source.
What are the official names of this protein?
Lytic chitin monooxygenase, EfCBM33A, Lytic polysaccharide monooxygenase, LPMO.
What are the subcellular locations of this protein?
Secreted.
Protein: NEP_I97A1
Sequence: MDSNTVSSFQDILKRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLSQKFEEIRWLIEEVRHRLRITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: MYCT1_DANRE
Sequence: MADNSTHPIMKILESFGLTDVILAFFLSMVVGLLLGALVYMILTWMSRRRASATITRIPVHQSRSTTRSSSPRSRLGYSRHSSGYDRRSNNSLASAAFSFHRQTSSSPIDYGDSTGRKSSFRASTFHPLLQCSQIAREAEEGAQGSLPRTPTLTTSPGAAGSTSTVSSMITPPRARNRPDSFWGNSNLRGFHAGQTPPPAYDSIIRAYQETTT
What are the official names of this protein?
Myc target protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MYCT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABZ_CLOBK
Sequence: MEKFLDINEIKRIIPHRYPFLLVDKITELEEGKSAVGYKNVTVNEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEEFKGKIAYFGGINKAKFRKKVVPGDELKLSIELTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDA_ECOHS
Sequence: MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: RL28_PROMT
Sequence: MSRVCQLTGTRANNGMSVSHSHIRTKKLQQANLQQRRLWWEEENKWINIRVTTRALKTIQKKGLGKYAKSLGVDLNKL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: TA2R4_MOUSE
Sequence: MLWELYVFVFAASVFLNFVGIIANLFIIVIIIKTWVNSRRIASPDRILFSLAITRFLTLGLFLLNSVYIATNTGRSVYFSTFFLLCWKFLDANSLWLVTILNSLYCVKITNFQHPVFLLLKRTISMKTTSLLLACLLISALTTLLYYMLSQISRFPEHIIGRNDTSFDLSDGILTLVASLVLNSLLQFMLNVTFASLLIHSLRRHIQKMQRNRTSFWNPQTEAHMGAMRLMICFLVLYIPYSIATLLYLPSYMRKNLRAQAICMIITAAYPPGHSVLLIITHHKLKAKAKKIFCFYK
What is the function of this protein?
Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5.  In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 4, T2R4, Taste receptor type 2 member 8, T2R8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
Protein: PPAC_STAAB
Sequence: MAKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQQDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMP2K_MOUSE
Sequence: MKKFSRMPKSEGSGGGAAAGGAAGGGLGGGFASSSMGVRVFAVGRYQVTLEESLAEGGFSTVFLVRTHSGIRCALKRMYVNNTPDLNICKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTGFTESEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDAGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSHNVHCLIRFMLEPDPECRPDIFQVSYFAFKFAKKDCPVSNINNSFLPSTLPEPMTATEAAARKSQMKARITDTIGPTETSIAPRQRPKANSTAATSSVLTIQSSATPVKVPAPGEFSNHKPKGALRPGNGSEVLMVQGPPQQPPQQHRVLQQLQQGDWRLQQLHLHRHPHHHHQQQQQQQQQQQQQQLQQQQQQQQQLLQNAYLQQYQHAMHQQHILQQQFLMHSVYQPQPPASQYPAMMQQYQQAFLQQQMLARHQQPAQQVSPEYLTSPQEFSPALVSYASSLPAQVGTIVDSSYGANRSVAEKEAVANFTNQKTISHPPDMSGWNPFGEDNFSKLTEEELLDREFDLLRSNRLGASTPSDKTVDLPPAPHSRPPEEPFASVPFISHSGSPEKKTTEHSPNQKSITANLTKNGGSSPLCKDQRAGKKTSENPVIRGQVQKGHDDSESDFESDPPSPKSSEEEQEDEDAQGEHGDFNDDDTEPENLGHRPLLMDSEDEEEDDKHSSDSECEQAKTKRGDTSSLRRDKPGVAPDTALLTPARSPADALTPSQEFDVFGAVPFFAAPAPQSLQHRGDGKNLSQHAFPEQEDFDVFTKAPFNKKVSVQDWPAVGPDARPLPARPRSVDIFGSTPFQPFSVSASKSESKEDVFGLVPFEEITGSQQQQKVKQRSLQKLSSRQRRTKQDVSKSNGKRHHGTPTSAKKTLKPPYRTPERARRHKKVGRRDSQSSNEFLTISDSKENISVALTDGKDRASVLPSDESLLDPFGAKPFHPPDLWHQPHQGLSDICVDHTTILPGRPRQNSVHGSFHSAETLRMDDFGAVPFTELVVQSVTPQQSQPVELDPFGAAPFPSKQ
What is the function of this protein?
May be involved in osteoblast differentiation.
What are the official names of this protein?
BMP-2-inducible protein kinase, BIKe.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRDR_CHLFF
Sequence: MQCPFCNHGELKVIDSRNAPEANAIKRRRECLNCGQRFTTFETVELTLQVLKRDGRYENFQESKLINGLNAASSHTRIGQDQVHAIASNVKSELLGKQNREISTKEIGELVMKYLKKADMIAYIRFACVYRRFKDVGELMEVLLSATPDMEK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: LSHB_RABIT
Sequence: MGTLQGLLLWLLLGTGGAQAPRGPLRPLCRPVNATLAAENEACPVCITFTTSICAGYCPSMVRVLPAALPPVPQPVCTYRELRFASIRLPGCPPGVDPEVSFPVALSCRCGPCRLSSSDCGGPRAQPLACDLPHLPGLLFL
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin subunit beta, Lutropin beta chain, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.