PharMolix/UniProtQA huggingface dataset:
Protein: LIPB_YERPA
Sequence: MMPRLQQHKIILRQLGLQPYAPVSQAMHNFTEFRTDTTPDEIWLVEHQHVFTQGQAGKAEHVLMPGDIPVIQSDRGGQVTYHGPGQQVMYVMVDLKRAKIGVRQLVTAIENTVIETLAHFNIDSHARPDAPGVYVEQQKICSLGLRIRRGCSFHGLALNIAMDLEPFQRINPCGYAGMQMTQVSALQPGVTVADVQPVLVREFTRQLGYPTAKLQPWSLSDYLLSSHSSSSVL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_THEVB
Sequence: MRLSQMLFVTLRDEPAEAEIPSHKLLLRAGYIRRIASGIYSYLPLMWRVLQKVSAIVREEMNRSGALECLLPQLQPAELWQESGRWDTYTKAEGIMFSLTDRAQRQLGLGPTHEEVITALAKDLIRSYRQLPVHLYQIQTKFRDEIRPRFGLMRGREFIMKDGYSFHADVASLKETYQVMYDTYSRILQRCGLTFRAVEADSGAIGGSGSHEFMVLAAAGEDEVLYTADGQYAANVEKAVSLPPDAVPTTYKTVATLDTPNAATIDALVEQLQCHPTQIVKNVLYRAVFDNGRVGLVLVSIRGDQEVNSVKLHNTLTSLAPNYGATKLLDLRLADAHTAQEWAATPIPFGYIGPDLEDAVIKADSQIIPQWIRIADRTVVELKRFITGANRDQQHRVGVNWGKSCPLPAIIADVRKAQAGDRACHDPTQHLEAARGIEIGHIFQLGTKYSEAMKATYTNEQGEEVPLVMGCYGIGISRLAQAAVEQHHDAQGIVWPLAIAPYQVIIVVPNIGDAQQMQAATDLYEQLQAAGIEVLLDDRDERAGVKFKDADLIGIPYRLVTGRAIANGEVELIIRATGAKSTLPLTEVVRYLQKEIAQQLAP
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_BURCJ
Sequence: MAKPAKRVAVTGAAGQIAYSLLFRIANGDLLGKDQPVILQLLDLPQAQAAVKGVVMELDDCAFPLLAGVVITDDPKVAFKDADVALLVGARPRSKGMERKDLLSANAEIFTVQGAALNEVASRDVKVLVVGNPANTNAYIAMKSAPDLPKKNFTAMLRLDHNRALSQLAAKSGKPVASIEKLAVWGNHSPTMYPDFRFATAEGESLLKLINDDVWNRDTFIPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGTNGKWVTMGIPSDGSYGIPEDIIYGVPVTCENGEYKRVEGLEIDAFSREKMDGTLAELLEERDGVAHLLKN
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: YIDD_CLOBM
Sequence: MKNLLICIIKMYRKYISPLKRPSCRFYPTCSQYSIEAIEKYGALKGTLISIKRILKCHPFNEGGYDPVK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OBG_ECO81
Sequence: MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTGETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAKPRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIENPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_BORPA
Sequence: MNLNATIFFQMLVFFVLGWFTMKFVWPPLTKAIDERRQKIADGLAAAEKGKADLAQAQARVSLIEASAKSETHARIIEAEKQAASVIEQARREAEAERARIVAQAAQDAAQEVQRAREALRDDVAALAVKGAEQILKREVDARAHAELLNQLKAQL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS4_PSEE4
Sequence: MARYIGPKCKLSRREGTDLFLKSGVRALESKCNIEAAPGIHGQRRGRQSDYGTQLREKQKVRRIYGVLERQFRGYYQAAASKKGATGENLLQMLECRLDNVVYRMGFGSTRSESRQLVSHKAISVNGKTVNIPSYQVRPGDVVSVREKSLNQLRIVQALELCAQRGRVEWVDVDAAKKSGVFKNVPARSDLSADINENLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GL23_ARATH
Sequence: MATSMIPIFVTFMLVAAHMALADTNMLQDFCVADLSNGLKVNGYPCKDPAKVTPEDFYFIGLATAAATANSSMGSAVTGANVEKVPGLNTLGVSISRIDYAPGGLNPPHLHPRASEAIFVLEGRLFVGFLTTTGKLISKHVNKGDVFVFPKALLHFQQNPNKAPASVLAAFDSQLPGTQVVGPSLFGSNPPIPDDLLAKAFGAAAPEIQKIKGKFPPKK
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein subfamily 2 member 3.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: FRSA_ECO57
Sequence: MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWKLTQDSCLLHQRVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITDWIEKRLC
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: KTHY_BURL3
Sequence: MASGKFITFEGIDGAGKTTHLQWFCERLQGKLAAAGRQVVVTREPGGTQLGEKLREILLNQPMDLETEALLMFAARREHLALVIEPALARGDWVVSDRFTDATFAYQGGGRGLPRDKLETLERWVQGGFQPDLTVLFDVAPQVASERRGAARMPDKFESESDAFFSRTRSEYLRRAEEAPHRFAIVDATQTIPEIRHQLERVLAAL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: Y5698_ARATH
Sequence: MVDLSKDLQFFKVFLPEFGSHELVIPPAFIDMLEKPLPKEAFLVDEIGRLWCVETKTEDTEERFCVFFTKGWQSFANDQSLEFGDFLVFSYDGDSRFSVTIFANDGCKKDVGVVSTTDRSRVSLDEEEPDDIFTKPDRMRDCDCGQSINRKRKRDSVNEDPHVLVDDKPEYVSTYKTKPEHSEKTQRTVNRAGDTCDISWFPEKKHNGFEESVYKPKHPHFVRNITRGSLQKLELPLTFLRSNGIELEEDIELCDESGKKWPLKILNHDRGFKFSHESWLCFCKSHEMILTNKCLFEFIVPSNGRCSEILVRIVSGRLPTTMTKNNYQVIDMQP
What are the official names of this protein?
Putative B3 domain-containing protein At5g66980.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRH_MYCLE
Sequence: MSAAAAGRGERLNHAGNPGHRSKYSRVLLKLGGEMFGGGQVGLDLDVVAQVARQIAEVVRGGVQVAVVIGGGNFFRGAQLQQRGMERTRSDYMGMLGTVMNSLALQDFLEKEGIATRVQTAITMGQVAEPYLPLRAVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVFVEDPRVNPEAELLTAISHREVIDRGLRVADATAFSLCMDNGMPILVFNLLTNGNIARAVAGEKIGTLVTT
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_IDILO
Sequence: MEEVTLDKLATDVGTTVDRLVQQFAEAGMTKKAGDSVNEEEKQKLLAHLNRQHGGGGSSEPSKMTLKRKTKSTLSVGGGRDSKSVQVEVRKKRTYVKRSASEEQEREEQERLAQEKEAEEAKLREEEKQREEEQQRKEAEAKAKAEREKAEKEKAEKEKLRKEKEKERQKAEAEKRAAMTPEEREAADKAKADAEKLKRQQEEEARKKAEKEAEAQAEEARKLAEENAKRWEEEEQKRKQQEKEDVHFTTSSTAQEAEDAQDFDEERKSRKRGKKRRRKDEESDDTPRREKRRKGARRGSSLQQGFNKPAQPVERDVKIGETITVGELANRMAVKASDLIKTMMKMGEMVTINQILDQDTAALVVEELGHKPALVKDNALEEEVLSDRQEGGEEAPRAPVVTVMGHVDHGKTSLLDYIRKAKVASGEAGGITQHIGAYHVETGHGMVTFLDTPGHAAFTSMRARGAGATDVVILVVAADDGVMPQTKEAVQHAKAAGVPLVVAINKMDKEGADPDRVKNELSQLEVIPEDWGGDVQFIPLSAHTGEGIDELLEAILLQSEVLDLRAEKTGMASGIVVESRLDRGRGPVATVLVQRGLLKQGDVVLCGLEYGRIRAMRDETGKEIKEAGPSIPVEILGLSGVPQAGDEATVVRDERKAREVANYRQGKYRDVKLAKQQKAKLENMFADMAEGDVAELNIVLKSDVQGSLEAISDALTKLSTDEVKVNIIGSGVGGITETDISLASASNAIVVGFNVRAEAAARKLVEQESVDLRYYSVIYDLIDEVKAAMSGMLQPEFKQQIIGLAEVRDVFKSPKIGAIAGCMVTEGVVKRSAPIRVLRDNVVIYEGELESLRRFKDDVQEVRNGMECGIGVKNYNDVKEGDQIEVFETIQIERTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL18_HUMAN
Sequence: MAAEPVEDNCINFVAMKFIDNTLYFIAEDDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED
What is the function of this protein?
Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (PubMed:10653850).  Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed:14528293, PubMed:25500532).  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (PubMed:10653850).  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore (PubMed:33883744).
What are the official names of this protein?
Interleukin-18, IL-18, Iboctadekin, Interferon gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=The precursor is cytosolic (PubMed:33883744). In response to inflammasome-activating signals, cleaved and secreted (PubMed:33883744). Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore (PubMed:33883744). In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation (PubMed:33883744). The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10 (PubMed:32272059).
Protein: RECR_ECOL6
Sequence: MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFSGRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAELCAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PTH_LEGPC
Sequence: MAIKLIVGLRNPGSAYEQTRHNAGAWLVTALAQRHNSHFKIDKKMQAELTEIDINNHPCRLVLPLSFMNHSGQTTRIISQFYKIEPGEILIVHDELDLPVGRIKLKTGGGHGGHNGLRDITAQLGTGVFHRLRIGIGHPGHKDLVHQYVLSRPSMHDRQQIYDAIDRGIAIIPIVLSGDMARAMNQVNA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3K_ORYSJ
Sequence: MASEQAAESYTVEELVAVNPYNPDILNDLEGFVNDQVSNQTYNLDANLSLLRLYQFEPERLSVQIVSRILIKALMAMPGPDFSLCLFLIPEHVQMEEQFKTLIVLSHYLETARFRQFWDEASKNRNILDVVPGFEQAIQSYAIHVLSLTYQKVPRPVLAEAINIEGLALDKFLEHHIANSGWVIEKGARSQLIVLPRNEFNHPELKKNTAETVPFEHVTRIFPVLS
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DVL2_HUMAN
Sequence: MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFFVDVM
What is the function of this protein?
Plays a role in the signal transduction pathways mediated by multiple Wnt genes.  Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors.  Promotes internalization and degradation of frizzled proteins upon Wnt signaling.
What are the official names of this protein?
Segment polarity protein dishevelled homolog DVL-2, Dishevelled-2, DSH homolog 2.
What is the protein family that this protein belongs to?
Belongs to the DSH family.
Protein: CCSA_ATRBE
Sequence: MIFSTLEHILTHISFSIVSIVITIHLITFLVDEIVKLYDSSEKGIIVTFFCITGLLVTRWISSGHFPLSDLYESLIFLSWSFSLIHIIPYFKNNVLILSKITGPSAIFTQGFATSGILTEIHQSGILVPALQSEWLIMHVSMMILGYAALLCGSLLSVALLVITFRKNRKLFYKSNGFVNESFLLGENVLENTSFSAKNYYRSQLIQQLDYWSYRVISLGFTFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWIVFAIYLHTRTNINLRGANSAIIATIGFLIIWICYFGVNLLGIGLHSYGSFTSTFN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: 1A1D_PYRHO
Sequence: MHPKIFALLAKFPRVELIPWETPIQYLPNISREIGADVYIKRDDLTGLGIGGNKIRKLEYLLGDALSKGADVVITVGAVHSNHAFVTGLAAKKLGLDAILVLRGKEELKGNYLLDKIMGIETRVYDAKDSFELMKYAEEIAEELKREGRKPYVIPPGGASPIGTLGYVRAVGEIATQSEVKFDSIVVAAGSGGTLAGLSLGLSILNEDIRPVGIAVGRFGEVMTSKLDNLIKEAAELLGVKVEVRPELYDYSFGEYGKITGEVAQIIRKVGTREGIILDPVYTGKAFYGLVDLARKGELGEKILFIHTGGISGTFHYGDKLLSLL
What are the official names of this protein?
Putative 1-aminocyclopropane-1-carboxylate deaminase, ACC deaminase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: BGL35_ORYSJ
Sequence: MGIRMGRRLLLITLLLGALLCNNVAYAKFSRYSFPKDFIFGTGSAAYQYEGAYKEGGKGPSIWDTFTHIPGKILNNDTGDVANDFYHRYKEDVNLLKDMNMDAFRFSIAWTRILPNGSLSGGINREGVAFYNSLINDVIAKGMIPFVTIFHWDTPPGSGKQIRRLPERKHSNMHEKDYADFAEVCFHEFGDRVKYWTTFNEPFTYSAYGYGGGVFASGRCAPYVSKSCGAGDSSREPYLVTHHIHLSHAAVVHLYRTRYQPTQKGQIGMVVVTHWFVPYDDTAADRGAVQRSLDFMFGWFMDPLVHGDYPGTMRGWLGDRLPKFTPAQSAMVKGSYDFIGINYYTTYYAKSVPPPNSNELSYDVDSRANTTGFRNGKPIGPQFTPIFFNYPPGIREVLLYTKRRYNNPAIYITENGGNNSTVPEALRDGHRIEFHSKHLQFVNHAIRNGWGDGYLDRFGLIYVDRKTLTRYRKDSSYWIEDFLKKQY
What are the official names of this protein?
Putative beta-glucosidase 35, Os11bglu35.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: TPIS_SULTO
Sequence: MKPPIILINYKAYENSYGEKGVEISKKIEKVSKDYGVPIIISVPATMIYKLSQILEIPVYAQHVDALRHGAHTGAILPEMIKDAGAKGSLLNHSERKIRLDEIHEAVTRIRDLGLESVVCADSYELVHPLALLKPNAILIEPPELIGSGRAVSKEKPEVITRAVNEIKKVEGVYLIAGAGITTGEDVYKAIELGADGIGVASAVMKSSTPEKIVEDFIINALKAIDRKK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLH1_DICDI
Sequence: MDFLKSLPPLQTTDSNSTTAAVNTTTTTATNTATTTATNTATTTTTTTTTNLNNLINESKKKIHRLTQEVVNKISAGEVIQRPSNALKELLENCLDAKSTTITVTVKDGGMKFLQIQDNGSGIRLEDMGIVCERFTTSKLTKFEDLRSIQSFGFRGEALSSISHVSHLKILTKTADSPCAYRACYLNGKLTPPSPNEQSSDPKPCAGVNGTQITVEDLFFNTPSRKNVLKNTVDEHSRIVLLMKKYAINNPTVSFILKKQGDPTPEVHTSGGQNSLEKDVIGSLYGTDLSKELKIITIDPNNPNPNNDDDDNISGSQIKNSNLNRLDFTMKGFFSSTNYNSKKINFILFINGRLVDSKNLKTGLEQVYSKYLPKGTHPFMFIRLLVPPKNIDVNIHPTKSEVKILHEEQIIEFIQQKVDQELSISSNSKTFSTQILLPGFDQDNVSSSQKKQKNSQSSSTQTKSTNNNNNPTSRKEPIEYAKDKIRSDSKSQTLDAFLNPMDYNNNNDSSIDDNDGSGIGRYDDVDGSAGAAGAGGKFNDNLIFNDNSENEAPRDIDNPLSSVTPIKSKEQRQQQSTTTTTTTTTTTATTKSNSPASKNDIKKLQEHTFITPRKTRKYKQVELTSIKTLISEFQSNVHDGLKEFFNDCVFVGCLDHSYALVQFGKKLYLINLENITKELFYQLSLLRFSDFDSIKFSQSLSIYSLLLVSLDSPLSGWMESDGPKDKIADYLTKLLISKKELLNEYFSIEINEDGELVGIPQVLDHYVPCTDNLPIFLLKLATEVEWEFEKECFAGIVKEISSFFKIEPSFLKLRDTQVNNQQQTNSTTTTNNINFIKKDGKEWIIQHLIFPAFRKLSPPKKFANDGSVIQITTLDNLYKVFERC
What is the function of this protein?
Heterodimerizes with pms1 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR).  DNA repair is initiated by MutS alpha (msh2-msh6) or MutS beta (msh2-msh3) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex.  Assembly of the MutL-MutS-heteroduplex ternary complex in presence of rfc and pcna is sufficient to activate endonuclease activity of pms1.  It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease exo1 to degrade the strand containing the mismatch (By similarity).
What are the official names of this protein?
DNA mismatch repair protein Mlh1, MutL protein homolog 1.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CMOB_SHEWM
Sequence: MISFSSFYKKIADSSLQHWLETLPAILGQWQREHKHGTLPKWEKVLNKLHYPNPDTLELKDSVTIGSGQQLTSGEQQKLENLLRIFQPWRKGPFSVHGINIDTEWRSDWKWERILPHLSPLNNRTVLDVGCGSGYHMWRMLGEGANHVVGIDPSTLFLCQFEAIKRLAGEEQPIHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRTGGELVLETLVIDGDENTVLVPEDRYGKMNNVWFLPSAAALALWLKKADFVDIRCVDIDVTSLAEQRSTDWMPNESLVDYLDPSNIDLTVEGYPAPKRATFIATKNQPNKDLI
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: KCY_DEIGD
Sequence: MIVTIDGVAASGKSSVASGVARALGVPYVSSGLLYRAATLLALEADLPLDDPTTLLPQLHAHPLRLEALPEGNRVWAGERELTAELHSTRVDQGVSAVAALPEVRAWVDAQLRALPAPFVAEGRDMGTHVFPHADAKFYLTASPRVRAERRAQERPEDVPTIEAALIERDRRDRLQSAPAPDAHVIDTGPLALEDVIGVILAALPARSA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2125_METS4
Sequence: MTFLRNPADRARLTGHEARLACRRGEIVGSTAGLAHGYVQANLAVLPKDLATDFLLFAQRNPKPCPIIGVSAPGDRRIPELGEDLDIATDVSGYRVWRHGEMVEERLDVADLWRDDLVAFAIGCSFSFEAAMVEDGLPLRHVEMGVRVPMYRTTVPCRPAGPFAGPMVVSMRPLTPAQAIRAVQITSRFPAVHGAPVHLGLPEAIGIRDLGRPDYGDPVRVAPDEIPVFWACGVTPQSVIAASKPSFAITHAPGAMLVTDRRNSEFAVL
What are the official names of this protein?
Putative hydro-lyase M446_2125.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: GALT9_CAEEL
Sequence: MLRYIIPRKKGTFVIAAFLTVAFFCIVAYHRNDRRRTKFQFPDIEKYAEELVRLPETWNGELHQIPNYTAPREGPGEKGKPVVLTGKDAELGQADMKKWFMNVHASDKISLDRDVPDPRIQACKDIKYDYAALPKTSVIIIFTDEAWTPLLRTVHSVINRSPPELLQEVILLDDNSKRQELQEPLDEHIKRFGGKVRLIRKHVRHGLIRAKLAGAREAVGDIIVFLDSHCEANHGWLEPIVQRISDERTAIVCPMIDSISDNTLAYHGDWSLSTGGFSWALHFTWEGLSEEEQKRRTKPTDYIRSPTMAGGLLAANREYFFEVGGYDEEMDIWGGENLEISFRAWMCGGSIEFIPCSHVGHIFRAGHPYNMTGRNNNKDVHGTNSKRLAEVWMDDYKRLYYMHREDLRTKDVGDLTARHELRKRLNCKPFKWFLDNIAKGKFIMDEDVVAYGALHTVVSGTRMCTDTLQRDEKMSQLLGVFHCQGKGSSPQLMSLSKEGNLRRENTCASEENGNIRMKTCSKKAQFNERWAYENKMIRNLKSGKCMSTANLKPGDNAIVVECDEKDEHQKWNFIDPAKA
What is the function of this protein?
Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis.  Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity).  In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested.  Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
What are the official names of this protein?
Probable N-acetylgalactosaminyltransferase 9, Protein-UDP acetylgalactosaminyltransferase 9, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9, pp-GaNTase 9.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.