PharMolix/UniProtQA huggingface dataset:
Protein: RBD2_YARLI
Sequence: MAQFPLFQKFQKAIQHPPALSLGLPIFLTVIFLLSQRYVWIEDDLELRSTALTNFELNRISFYPLVHATWFHLLLNLVALQPIVSQFERVNGTVRTGIVLNILAVVTAIPWCLLSIGFFPDEAVLGSSAWIFSFMGYWAIRESSKQPTTQLAPNLVVPTWLLPIIYLVVIAIVIPSSSFIGHLLGLIAGWMMALGYLDVLIEPSSKVVLWIENKISRVIDLIPSSIVTFYREEGALDTRAAARADTNRSLSVSGGNFLGFQANSSQADLEAGTRSRGNSSVDPTTSFPGTGQTLGTQ
What is the function of this protein?
Probable serine protease.
What are the official names of this protein?
Rhomboid protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Protein: FUB6_FUSO4
Sequence: MGGEVSNKTWVFKQSPSGLPEPGVHTAFEDRPLSLVAPPGGLVINLLTAGLDPHQRDRMRGAGNVDYVPGYEVNEPITNFSIAKVIRSDNAAFEEGSLIAGSLPIAEYGIIPKELIDARAMASPLVWKVSNDYNLDVKHYVGTLGLAGMTAWNSFYGLVKPVKGETIWVNAASSSVGEVVVQLAKIEGMKVIASVSSDDKLDYVVNELGADVGFNYRKEPVGKALKRLAPDGLDVVFENVGGDHFQAAIENMKWFGRIISCGTASQYNKPVEEQYGVTNLSEIFRRRIKIQGFIFWDDNIYTDNIENFKATMPKWVSEGKIKSRYTQFEGIEQADKAFLSMFTGGSHGKTVLKISDP
What is the function of this protein?
Dehydrogenase; part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties (PubMed:25372119).  L-aspartate is suggested as fusaric acid amino acid precursor that is activated and further processed to O-acetyl-L-homoserine by cluster enzymes aspartate kinase FUB3 and homoserine O-acetyltransferase FUB5, as well as enzymes of the primary metabolism (By similarity).  The polyketide synthase (PKS) FUB1 generates the triketide trans-2-hexenal which is presumptively released by the hydrolase FUB4 and linked to the NRPS-bound amino acid precursor by NAD(P)-dependent dehydrogenase FUB6 (By similarity).  FUB1, FUB4, and the non-canonical NRPS Fub8 may form an enzyme complex (By similarity).  Further processing of the NRPS-bound intermediate might be carried out by FUB6 and the O-acetylhomoserine FUB7, enabling a spontaneous electrocyclization to close the carbon backbone of fusaric acid (By similarity).  Dihydrofusaric acid is likely to be released via reduction by the thioester reductase (TR) domain of FUB8 whereupon the final oxidation to fusaric acid may (also) be performed by the FMN-dependent dehydrogenase FUB9 (By similarity).
What are the official names of this protein?
Dehydrogenase FUB6, Fusaric acid biosynthesis protein 6.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: LIPR1_MOUSE
Sequence: MLILWTIPLFLLGAAQGKEVCYDNLGCFSDAEPWAGTAIRPLKLLPWSPEKINTRFLLYTNENPTAFQTLQLSDPSTIEASNFQVARKTRFIIHGFIDKGEENWVVDMCKNMFQVEEVNCICVDWKRGSQTTYTQAANNVRVVGAQVAQMIDILVRNFNYSASKVHLIGHSLGAHVAGEAGSRTPGLGRITGLDPVEANFEGTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQMVGHFDFFPNGGQYMPGCKKNALSQIVDIDGIWSGTRDFVACNHLRSYKYYLESILNPDGFAAYPCASYRDFESNKCFPCPDQGCPQMGHYADKFANNTSVEPQKFFLNTGEAKNFARWRYRVSLTFSGRTVTGQVKVSLFGSNGNTRQCDIFRGIIKPGATHSNEFDAKLDVGTIEKVKFLWNNHVVNPSFPKVGAAKITVQKGEERTEHNFCSEETVREDILLTLLPCKTSDTM
What is the function of this protein?
May function as inhibitor of dietary triglyceride digestion.  Lacks detectable lipase activity (in vitro) (By similarity).
What are the official names of this protein?
Inactive pancreatic lipase-related protein 1, PL-RP1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in acinar cells.
Protein: RL14_CLOBJ
Sequence: MIQQQTRLKVADNSGAKEIMCIRVLGGSHRKWGNIGDVIVASVKSATPGGVVKKGEVVKAVIVRSVKGLRRADGSYIKFDENAAVIIKDDKNPKGTRIFGPVARELRDKEFNKILSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ERR2_YEAST
Sequence: MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL
What are the official names of this protein?
Enolase-related protein 2, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
Protein: DMS1D_WHEAT
Sequence: MGAGEKTAAGMPRIGMGTAVQGPKPDPIRRAVLRAIEIGYRHFDTAAHYETEAPIGEAAAEAVRSGAVASRDELFITSKLWCSDAHRDRVVPALRQSLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAEDFVPFDMRAVWEAMEECHRLGLAKAIGVANFSCKKLETLLSFATIPPTVNQVEVNPVWQQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQEIAASRGKSVAQVCLRWVYEQGDCLIVKSFDEARMRENLEVDGWELTEEERLRIAEIPQRKINLGKRYVSEHGPYKSLEELWDGEI
What is the function of this protein?
Catalyzes the reduction of a 3''-keto intermediate during the biosynthesis of 2'-deoxymugineic acid (DMA) from L-Met.  Involved in the formation of phytosiderophores (MAs) belonging to the mugineic acid family and required to acquire iron.
What are the official names of this protein?
Deoxymugineic acid synthase 1-D.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: GP3_SOLLC
Sequence: MHTKILLPSCILLLLLFTLSSLDVVVAKDGDESGNPFTPKGYLIRYWNKHVSNDLPKPWFLLNKASPLNAAQYATYTKLVADQNAFTTHLQSFCSSANLMCALDLLPSLEKHKGDVHFVSYGDKNFTNYGTKESGLGFNSFKNYTEEENFPVNSFRRYGRDSPHDNQFDNYGAPGGNTPVQSFNSYSTNTPGGSGQFTNYAPGSNVPDLHFTSYSDHGTGGEQDFKSYGNDGNAGQQSFKSYGKDGNGADSQFTTYGNNTNVDGSDFTNYGEAANGENQNFTSYGFNGNNPASSFNNYGVGGNGPSEAFNSYRDQSNVGDDTFTTYVKDANGGEANFTNYGQSFNEGTDVFTTYGKGGNDPHINFKTYGVNNTFKDYVKDTATFSNYHNKTSQDLASLSEVNGGKKVNNRWIEPGKFFREKMLKSGTIMPMPDIKDKMPKRSFLPRAIAAKLPFSTSKIDELKKIFHAANDSQVAKMIGDALSECERAPSPGETKQCVNSAEDMIDFATSVLGRNVVVRTTENTNGSKGNIMIGSIKGINGGKVTKSVSCHQTLYPSLLYYCHSVPKVRVYEADILDPNSKAKINHGVAICHVDTSSWGPRHGAFVALGSGPGKIEVCHWIFENDMTWATAD
What is the function of this protein?
Non-catalytic subunit of polygalacturonase.
What are the official names of this protein?
Polygalacturonase non-catalytic subunit AroGP3.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Secreted, cell wall. Note=Associated to the cell wall.
Protein: T229B_CHICK
Sequence: MAAAEPLTAFSRWYLYAIHGYFCEVMFTAAWEFVVNFNWKFPGVTSVWALFIYGTSILIVEKMYLYLKDKCHILVRCFIYTLWTYLWEFTTGLILRQFNACPWDYSQFDFDFMGLITLEYAIPWFCASFIMEQLVIRNTLRLRFDETAEPGAPTVPVALANGHVKTD
What are the official names of this protein?
Transmembrane protein 229B.
What is the protein family that this protein belongs to?
Belongs to the TMEM229 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1128_MARMM
Sequence: MSQSDDRIVRIDLDGASMGPGDVNADHERRVAIADLLEGNRFRPDGEVDGPYALRLAIEHDRLVFDVRLEDDTPVHGFMFALGPLRRIVKDYFLICESYYEAVRDAPLERIEAIDMARRGVHNEGSTLLRERLVGKIDVDFDTARRLFTLICALHRRAAS
What are the official names of this protein?
UPF0262 protein Mmar10_1128.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: TBCD7_HUMAN
Sequence: MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVWKVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS
What is the function of this protein?
Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions.  The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB.  Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1.  It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
What are the official names of this protein?
TBC1 domain family member 7, Cell migration-inducing protein 23.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Note=Localizes in the cytoplasmic vesicles of the endomembrane in association with TSC1-TSC2 complex.
Protein: MAP10_HUMAN
Sequence: MAASLSERLFSLELLVDWVRLEARLLPSPAAAVEQEEEEEEKEQGEASSPRGLCPAVAFRLLDFPTLLVYPPDGPGAPAAEPWPGVIRFGRGKSCLFRLQPATLHCRLLRTPLATLLLQLPPGRPTPTPQLLGACDISLATAAHRVVGPAASGCSHRHRGRFPLHNRVGERTGDIALAYRLTDLGSRLLSQLERPLTFTRTGGGAEVSPQTQQERQQLQQPASQPSPKEADKPLGELEIPEAQKDLKEMVKSKAECDNVGSVENGKTNSVVTCSGAGNGRNVSSLNEEVTELDMETNIFCPPPLYYTNLTQEKPPPAQAKITIEPQMNAPEEMDDASPEKKRVNPPAHRSCLKHPSSAAHEHPPMLVNPPHIQNIGATNQTCQTEQNRINTIRQLPLLNALLVELSLLYDQPVTSPAHIHPHLAWLYRTEDKKSPESSAKSTCRSEAKKDKRSVGGCEKSVSLQYKKNQIENYKEDKYSEKSSGALHKRVPKGRLLYGLTNTLRLRLKLTNPDMLVVHEKRELYRKRQSQMLGTKFRIPSSKVKLLSSAEQSQKPQLPEDKYLDSDASFTENSDTSRQISGVFDEPSTSKETKLKYATEKKTVDCSKNRINNVSLEEVVSPANSIIPERLTPTNILGGNVEMKIQSPCVFQQDAVVDRIVDKEIDIRQVKTTDNDILMADISDKRTGKNSCYENISELKYSDDLSSPCYSEDFCTSEDTSRSFKAHDSSSRTENPKHSQYTSKSSDTGVSKKKNSSDRSSILSPPFSAGSPVHSYRKFHISKTQDKSLEEASSISASDLSSTHWTEQKENQIDQNSMHNSEITKRAQDISVKTRSSWKSLEKSQSPQTSQVSSYLPSNVSELNVLDSSTSDHFEEGNDDVGSLNISKQCKDICELVINKLPGYTM
What is the function of this protein?
Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis.
What are the official names of this protein?
Microtubule-associated protein 10, Microtubule regulator of 120 KDa.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Localized at stabilized microtubules (MTs) during interphase and to the mitotic apparatus during mitosis. Localized at spindle poles in metaphase and spindle midzone during telophase. Colocalized with Polo-like kinase PLK1 to the center of spindle midzone. Localized at the midbody during cytokinesis. Colocalized with acetylated-tubulin at MTs.
Protein: NUSB_LEPIC
Sequence: MSARRTSREIAVMALYQLELTQPPLKEVLKFKWYDKKTEPEERDFAVSIVNGVVKNQEQIDTLIKKYSKNWDFSRISIVNKAILRLSIYALLYTWEVPKNVTIDEAVELTKEFESEESARFVNGVLDAILKNEIKSDG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ILVC_CHLPD
Sequence: MNVYYEQDADLGFLQGKNIAVLGYGSQGHAHALNLKDSGMNVCVGLRSDSTSCQKARDAGLEVKTIADAVTWADIVMVLLPDQNQKAIYEAEIAPNLVPGNTLAFAHGFNIHYKQIIPQETINVIMIAPKSPGHLVRRTFTQGNGVPCLIAVHQDYTGEAKQQALAWAKGLGGTKAGVIETTIKNETETDLFGEQAVLCGGSAELIKAGFETLVEAGYPEELAYFECMHELKLIVDLYYEGGLSRMNYSVSDTAEYGGMTRGPRLITPAVKAEMKKILEEVQDGRFAREFIDECQNGYPNLNRLREENRTHSIEKVGARLREMMSWLIKK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YAEP_ECO24
Sequence: MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALSEAVREKAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein YaeP.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: RS27A_NANEQ
Sequence: MAQVWKYYEIKDGKLIRKKKVCPRCGSFMAEHKDRYHCGKCGYTEWKVERPKIVIHGATIE
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: HSP1_RABIT
Sequence: MVRYRCCRSQSRSRCRRRRRRCRRRRRRCCQRRRVRKCCRRTYTLRCRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1, Cysteine-rich protamine.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS14_SODGM
Sequence: MAKQSMKAREVKRVKLADKFFAKRAELKTIISDVNASDEDRWDAVLKLQTLPRDSSPSRQRNRCRQTGRPHAFLRKFGLSRIKVREAAMRGEIPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RECG_STAAW
Sequence: MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNNSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKSSDEAIEIDYGLDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEIDVLVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD
What is the function of this protein?
Critical role in recombination and DNA repair.  Helps process Holliday junction intermediates to mature products by catalyzing branch migration.  Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity.  Unwinds branched duplex DNA (Y-DNA) (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase RecG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecG subfamily.
Protein: CYB_GALDE
Sequence: MTNTRKQHPLAKIINHSFIDLPAPSNITAWWNFGSLLGLCLTVQIITGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFMCLFAHIGRGLYYGSFTFLETWNIGIALLLAVMATAFMGYVLPWGQMSFWGATAITNLLSAIPYMGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGLPSDSDKIPFHPYYMIKDLLGLIILLLTLFSLVMFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLSSILILALIPFMHTAKQRSMMFRPLSQCLYWMLVADLLILTWIGGQPVENPFIMIGQVASITYFFIILILMPLTNTLENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: APCA_AROAE
Sequence: MYTVDIDTGGTMTDALVSDGEQRHAIKVDTTPHDYTVSFNGCLSEAAKRLGYPSTEAFLAKVGMIRWSSTITTNVLGERRGSKVGLLVTEGNEENLYGTVQSPVVGELVDERNIIGLPSNPTAVDILSGVKQLLEGGVRRICVCLANAFPDNGAEREIKAVIEDQYPDHIIGAVPVLLGSEMAPLRHDQTRVHYSLMNAYTHTQLATSLFKAEDLLRDDHNWTGPLLIGNTNGGVARIGKTKSVDTIESGPVFGTFGGAYMARLYGLKDVVCFDVGGTTTKASIIRDGQPMFQRGGELMEVPVQSSFAMLRSAVVGGGSIARVRDKSVTLGPESMGAAPGPACYGLGGNEATLTDALLALGYLDPNNFLGGRRQLKVDLARAAIERNVAKPLGVSLEVAALSIRDEAVAMMTELLQATLAEAKLTAQDAALFAFGGNGPMFAAFVAERLGVQAAYAFNLGPVFSAFGSAISDVVHVYERGVDLRWNATVKGQLLPTLDALQTQAERDLKGESFDPAKAAYVWELDFGTTEAEVSTVRAELAQSAASTVLDALTQAVTAAGVASLPLLGARLSSRFVVGAHGMKKRADRVPAEAPASREMRFNGASEAASPVYRWETMNVGDIAVGPAVVNGSTLTCPIPPRWQLRVDDYGNAELSRAQ
What is the function of this protein?
Catalyzes the carboxylation of acetophenone to form 3-oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene.  Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates.
What are the official names of this protein?
Acetophenone carboxylase alpha subunit, Acetophenone carboxylase 70 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the oxoprolinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOAB_BACTN
Sequence: MTLQEIKDQVLAGFDISSAQATWLANMADSEALYAAAHEITITCASHEFDMCSIINAKSGRCPENCKWCAQSSHYKTQAEIYDLLPAEECLRQAKYNESQDVNRFSLVTSGRKPSPKQISQLCDAARLMRKHSSIQLCASLGLLNEEELRALHTAGITRYHCNLETAPSYFPTLCSTHTQEQKLATLDAARRVGMDICCGGIIGMGETMEQRIEFAFTLAELNVQSIPINLLSPIPGTPLENEKALSEEEILRTIALFRFINPTAFLRFAGGRSQLTPEAMRKALFVGINSAIVGDLLTTLGSKVSDDKKMILEEGYHFADSQFDREHLWHPYTSTTDPLPVYKVKRADGATITLEDGRTLIEGMSSWWCAVHGYNHPVLNQAAKDQLDKMSHVMFGGLTHDPAIELGKLLLPLVPPSMQKIFYADSGSVAVEVALKMAVQYWYAAGKPDKNNFVTIRSGYHGDTWNAMSVCDPVTGMHSLFGSSLPVRYFVPAPSSRFDGEWNPDEIIPLRETIEKHSKELAALILEPIVQGAGGMWFYHPQYLREAEKLCKEHDILLIFDEIATGFGRTGKLFAWEHAGVEPDIMCIGKALTGGYMTLSAVLASNQIADTISNHAPKAFMHGPTFMGNPLACAVACASVRLLLDSGWAENVKRIEAQLKEELAPARKFPQVADVRILGAIGVIQTERSVSMAYMQRRFVEEGIWVRPFGKLVYLMPPFIISPEQLSKLTSGVLKIVREM
What is the function of this protein?
Catalyzes two activities which are involved in the biotine biosynthesis: the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism, and the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA).
What are the official names of this protein?
Biotin biosynthesis bifunctional protein BioAB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
Protein: IHFB_CUPMC
Sequence: MTKSELVEKLAARFPQLLLRDADISVKTILDAMSEALADGHRIEIRGFGSFGLNKRPPRVGRNPKSGERVLVPEKRVPHFKAGKELRERVDRTVTQGGGMNGNGHAPHGKTGQSQLGSQSPASLHDDGQLNLVRS
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RL17_ECODH
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HDED_SHIFL
Sequence: MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFVSGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVLSGFLVAVAYLLIGYFFIRAPELGIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIVIAWIFLGATPMVSVTLVSTLVGIELIFSAASLFSFASLFVKQQ
What are the official names of this protein?
Protein HdeD.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURI_MYCTO
Sequence: MNSPLAPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLTIPEIRAHALAIGDDLVGRGVKALVIACNSASSACLRDARERYQVPVVEVILPAVRRAVAATRNGRIGVIGTRATITSHAYQDAFAAARDTEITAVACPRFVDFVERGVTSGRQVLGLAQGYLEPLQRAEVDTLVLGCTHYPLLSGLIQLAMGENVTLVSSAEETAKEVVRVLTEIDLLRPHDAPPATRIFEATGDPEAFTKLAARFLGPVLGGVQPVHPSRIH
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: RUVC_PSEAB
Sequence: MTLILGIDPGSRITGFGVVRETARGCEYVASGCIRTGNGPLHERLHVVFRSVREVIRTHGPTALSIEQVFMARNADSALKLGQARGAAIVAAMEEGLSVAEYTASQVKQAVVGTGGADKQQVQMMVMHLLKLTQKPQIDASDALAIALCHAHTQQSLVPHGLVGARRRGGRLRL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ISPE_CHLT3
Sequence: MSKTVNAYAKINLALFITGKLPNGYHTLETIFAPINWYDRLTFEPSETIEMACTNAELPTDDSNLCIKAAKRLQTESGSQKGVKISLEKNVPFGAGLGGGSSDAAATLNALNELWELSLPSETLHKLATELGADVPYFLEMPALALGTGIGEELTDLQVAFPFSIVTVFPETAISTAWAYQNFKQNFDRLLPDAATEIQIVCETGDLGRMQQFENDFESIVYENYAEVKKLRDDFVEAGSGFTRLSGSGSAVFGVFADDEKATACYEAMRKRYPTSLTPKSFKMK
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: DNLJ_SHIFL
Sequence: MESIEQQLTELRTTLCHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKNNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGVPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLEQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKLAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.