PharMolix/UniProtQA huggingface dataset:
Protein: HTPG_SALAI
Sequence: MSGETLEFQAEARQLLQLMVHSIYSNKDVFLRELISNASDALDKLRLASMRDKDLDVDTSDLHIAIEVDQDARTLTVRDNGIGMTRDEVVQVIGTIAKSGTAELLRKLRETTDAETSQELIGQFGVGFYAAFMVADRVVLVTRQAGEADGTHWESSGEGTYTIAPATDVPQGTAVTLHLKPVDSEDNLHDYAAEWTIRQIVKRYSDFIAHPIRMAVERPGSDDSEPTTEVQTLNSMKALWARPRDEVEPAEYHEFYKHVSHDWADPLEVVHMRGEGTFEYEALLFLPTHAPLDLFSPQGRRGVQLYVKRVFIMDDCEALMPGYLRFVKGVVDAHDLSLNISRELLQQDRQIQVVRRRLVKKVLATVKDLKANQPEKYRTFWTEFGAVVKEGLIDDTENRDSLLEILSVASTHDPAEPTDLTGYVNRMKDGQSEIYYATGENRTTIENSPHMEAFRAKGFEVLLLTDPVDEVWVERVGEYDGKTLRSVAKGQVDLDTDEERSAAEAERERQRTEYADLLTWLGSALADQVREVRLSARLTTSPACVVGDAHDVTPTLEKMYRAMGHEVPQVKRILELNPTHPLVSGLRKAREQGATEDSLTETAELLYGMALLAEGGELADPSRFTRILAERLARTL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGLO7_ARATH
Sequence: MKRSMRSHLAKQTRSVIFTGYPVIGSQDRIMSSGACLDSHQNGLITSCPWDPRIKGEFFYQTALSVPLTHVKDFINDIKALVKIEPKSLCGLELNYGVLVRYVTSSPAYLRKEEKALDFDLTYYRSKDDPWTPRLYEDYMEEIEQMAILKYNALPHWGKNRNLAFDGAIKKYKNANTFLKVKERLDPWGLFSTEWTDQILGLKGNVTIVKQGCAPEGLCICSDDSHCAPNKGYMCRPGKVYKEARVCTLVTA
What is the function of this protein?
May be involved in the biosynthesis of ascorbic acid.
What are the official names of this protein?
Probable truncated L-gulonolactone oxidase 7, mitochondrial, AtGulLO7.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL7_CALS4
Sequence: MSKEEILQAIKNMTVLELAELVKALEEEFGVSAAAPVAVAAAPAAGAPAAAPAEEKTEFDVILQEVGSDKIKVIKVVREITGLGLKEAKDLVDSVPKPIKEGVSKEEANQIKAKFEEVGAKVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SYL_MALP2
Sequence: MYNHNLVEKKWRKIWKDSNLHTFKDNLKKPKFYALDMFPYPSGAGLHMGHVKSYTPTDVYARFKRYQGYSVLHPMGWDAFGLPAEQFALATKNHPATFTDQNINNFKLQIDQLGFWFDWNKEVNTTDPNFYKWTQWIFIKLFENGLAEIKDIDVNWCQELGTVLANEEVLTDEKGNKVSERGKYPVIKKPMKQWVLKITKFADQLIDDLELTDWTVGLKNIQKKWIGKSIGATVKFKIQNSDSEIEVFTSRPDTIFGVSFIGLSSDHELVLKEKTKNKKIEAFLNELSSLKEYERTAINVEKKGVLLDIKAIHPITKQLVPVYVCNYVLSNYGNGAIMGVPAGDKRDYDFAKLFNLEIKEIIKDHPAPYEEDGIHINSDFLNGLNNEDAIAKIVEYLEKNKIGKKQVNYKLKDWLFSRQRYWGEPFPVLFDEKGNIIVEKNLPLLLPETNDIKPSGTGESPLANLTEWVNVKIDSKLYRRETNTMPQWAGSCWYYLAYLLKDGDSYLPLDSKQAYEIFKRWLPVDIYIGGQEHAVLHLLYARFWHKFLHQINVVPNKEPFYKIINQGMILVNGEKMSKSKGNVVNPSDFVVSHGADALRLYMMFMGPITASLPWEESGIDGMYKWVQRVYRLFETKQIDKNFNDENLEKKYHQFVKKASEFMENFDFNLVISEMMIFINECYKYEKINYDYMLNFCVILSCFAPFITEEINEVFLKNKKFISDNLWPKYDEKKIVETTIKIPVQINGKIREVLEINLGATQKDVVDLAIKNEKIIKWIENKKIVKEIYIENKILNLIIK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XGPT_CERS1
Sequence: MKERLPHEKGFHVSWDQIHRDSRALAWRLDGQGPDNGSWRAVVGITRGGLVPAMIVSRELDIRTVDTISVKSYNWQEQQAPTVIKAPQAELMGDGHGILIVDDLVDSGKTLELVRTLYPRAHFATVYAKPSGRPMVDTYITEVSQDTWIFFPWDMALQYVEPYRGRD
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DNAJ_ECO81
Sequence: MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLNEKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_CLOBK
Sequence: MKVKDFDFYLPEELIAQHPMEKRDEARLLVLDKETGEIEHKIFKDILDYLTPNDCLVLNNTRVLPARLIGSKEETGGKMEFLLLKRKEKDVWETLVKPGKRAQIGARFIFGNGELKAEVIGMGEEGSRIVKFYYEGIFEEILDQLGQMPLPPYIKEKLDDKEMYQTVYSKEEGSAAAPTAGLHFTEELLKKIEEKGVKLAFLTLHVGLGTFRPVKVEDIQEHVMHSEYYKMDKKTAEIINDTKENGGRVIAVGTTSCRTLETIADIEGKVGEQSGWTDIFIYPGYKYKVVDALITNFHLPQSTLLMLVSALAGKDNIMNAYNVAVEKEYRFFSFGDAMFIK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_AZOVI
Sequence: MESLSQHTPMMQQYWKLKREHPDQLMFYRMGDFYELFYEDAKKAAKLLDITLTARGQSAGKSIPMAGIPFHSVEGYLAKLVKLGESVAICEQIGDPATTKGPVERQVVRIITPGTVSDEALLDERRDNLLAAVVGDERLFGLAILDITSGRFNVQEIQGWENLLAELERLNPAELLYPDDWPAGLPLEKRRGAHRRAPWDFDFDSAYKSLCQQFATQDLKGFGCDGLGLAIGAAGCLLAYARETQRTALPHLRGLRHERLDDTVILAGASRRNLELDVNLSGGRDNTLQSVIDRCQTAMGSRLLGRWLNRPLRDRAVLEARQDTVACLLQDYRFESLQPQLKEIGDVERILARIGLRNARPRDLARLRDALAALPQLQTALSPLEAPHLQALAGNIRTYPELAELLRRAIIDNPPAVIRDGGVLKQGYDAELDELLSLSENAGQFLMDLEAREKARTGLPNLKVGYNRIHGYYIELPRVQAEQAPADYIRRQTLKGAERFITPELKAFEDKALSAKSRALAREKALYEELLEILIAQLAPLQETATALAELDVLANLAERALNLDFNRPRFVEEPCLRIRQGRHPVVEQVLDTPFVANDLELDDNTRMLIITGPNMGGKSTYMRQTALIVLLAHIGSFVPAQSCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNASERSLVLMDEVGRGTSTFDGLSLAWAAAEHLAGLRAWTLFATHYFELTVLAESQPVVANVHLSATEHNERIVFLHHVLPGPASQSYGLAVAQLAGVPGPVISRAREHLARLEATSLPHEAPLREAGKPQPPIQSDLFASLPHPLMEELARLKPDDLSPRQALELLYSWKTRL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FPG_YERPE
Sequence: MPELPEVETSRRGIEPYLVGQTILYAVVRNARLRWPVSDEILTLSDQPVLSVQRRAKYLLLELPKGWIIIHLGMSGSLRVLSEETAAEKHDHVDLVVSNGKILRYTDPRRFGAWLWAKDLETSNVLAHLGPEPLSDEFTAQYLFDKSRNKRTLIKPWLMDNKVVVGVGNIYASESLFAAGILPDRAAGSLTDAESVLLVATIKAVLLHSIEQGGTTLRDFLQSDGKPGYFAQELQVYGRAGEPCRQCGHPIEIAKHGQRSTFFCRHCQH
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: NAA60_MOUSE
Sequence: MTEVVPSSALSEVSLRLLCHDDIDTVKHLCGDWFPIEYPDSWYRDITSNKKFFSLAATYRGAIVGMIVAEIKNRTKIHKEDGDILASSFSVDTQVAYILSLGVVKEFRKHGIGSLLLESLKDHISTTAQDHCKAIYLHVLTTNNTAINFYENRDFRQHHYLPYYYSIRGVLKDGFTYVLYINGGHPPWTILDYIQHLGSALANLSPCSIPHRIYRQAHSLLCSFLPWSSISTKGGIEYSRTM
What is the function of this protein?
N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol.  Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met.  Required for normal chromosomal segregation during anaphase.  May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences.
What are the official names of this protein?
N-alpha-acetyltransferase 60, Histone acetyltransferase type B protein 4, HAT4, N-acetyltransferase 15, N-alpha-acetyltransferase F, NatF.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. NAA60 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Probably forms a intramembrane hairpin-like structure in the membrane.
Protein: URE3_PSEPF
Sequence: MDLTPREKDKLLIFTAGLVAERRLARGVKLNYPEAMAYISAALLEGARDGQTVAELMHYGTTLLTREQVMEGIPEMIPEIQVEATFPDGTKLVTVHQPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMCPB_ORYSJ
Sequence: MASPRSAGGVGGGGGGGGGSGGAAAGDDAIWSKLREAGFDEESLKRRDKAALIAYISRLESEIYQYQHNLGLVLMERKELTSKHEQLRAASESAEIMHKRERAAQQSALAEARKKEENLKKSLGIQKECVANLEKALHDMRGETAETKVSYESKLAEALQLMEAAHKKFDEAEEKLLLAKSLEAESIRTHNAALRSLHDIDDREDQLRRDRISCELENEAKEKEISLQRKSLNDMKKILHEKEEVLLKEQALLNQRDENILERLAYVTHSEKRVEEEKNILEAERKVLLEEKYKLELKMEAIVSREEALIQKESLLDKRESELLILQETIASKERAEIERLNQEQAIALERRKHDFESEMANKQMSFDAAMEVTRNALHQRECALSEQESVVVQRSQNLDLQLAELASKEKALAGRSDELKEEEEKLLLHREAIHNELQKEREEIQRIKSDLEKEKAFFEEEKREAIQAQQDLAITQADRDELLTLQMKLKEEIDSLRAQKRELMADADRLQAEKERFEIEWELIDEKKEELQKEAIRIAEERRAITEYLKNESDIIKQEKDNLRVQFKSNSETLSREHKEFMSKMQQEHASWLSKIQQERQDLKRDIDIQRVELLNSAKARQMEIDSYLREREEEFEQKKAKELEHINSQKEMINTKLEHVAVELQKLKDERKEATLERERREQELSEIKGTIEALNNQREKLQEQRKLLHSDREAITVQIQQLNVLEELKIDSENKQLSLLQHDKSKLGSDINVKDNHHDNSHSSPKQRFGRKLDLSPVSTPISWVRKCAQVIFKRSPEKSASHDQFVQNGVPKKVGDSVDVEDVNLDFAKVGQKRLNHLVSCDQTEVLEPKRKHRRSTIQKVNGGEITSNCLSALEEKCSKNEHDEAPLGLSNTCKEHEYGDKGPENLTKPGEPASSVDVPYVNGIVDNSDSVQEEPSVEATVSATETSNVDGPEDNNDSDEEDEEEEEEKTSSAKKLWRFLIT
What is the function of this protein?
Architectural component of nuclear structure that plays different roles in controlling nuclear size and morphology (Probable).  Involved in the modification of chromatin accessibility by interacting with SWI3C, a component of the chromatin-remodeling complex, to thus reduce the suppression effect of the complex (PubMed:32129897).  Acts as positive regulator of drought resistance and modulates root growth (PubMed:32129897).  Positively regulates the expression of genes related to root growth and drought resistance (PubMed:32129897).
What are the official names of this protein?
Nuclear matrix constituent protein 1b, OsNMCP1b, Nuclear matrix constituent protein 1, OsNMCP1.
What is the protein family that this protein belongs to?
Belongs to the CRWN family.
What are the subcellular locations of this protein?
Nucleus matrix. Nucleus lamina. Note=Localizes predominantly at the nuclear periphery.
Protein: F172A_MOUSE
Sequence: MSISLSSLIFLPIWINMAQMQQGGSNETEQTAALKDLLSRIDLDELMKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITRYVYELLESDCNLKKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAMDEGYGVIVLNPNENYIEVEKQKMHKQSSSSDGTDEPAGKRERRDKVSKETKKRRDFYEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAQAAAENVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFAEASEAKSSSQKPALTRRSHRIKHEEL
What is the function of this protein?
Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7.  Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface (PubMed:29311329).  May have hydrolase activity (PubMed:29311329).
What are the official names of this protein?
Cotranscriptional regulator FAM172A.
What is the protein family that this protein belongs to?
Belongs to the FAM172 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endoplasmic reticulum.
Protein: BCHL_METEP
Sequence: MNIAIRNPVPIRREEGSLQVGLDPNDRIETAKVFAVYGKGGIGKSTTSSNLSVAFSKLGKRVLQIGCDPKHDSTFTLTKRLAPTVIDALEAVNFHSEELRAEDFVVEGYNGVKCVEAGGPPAGTGCGGYVVGQTVKLLKEHHLLEDTDVVVFDVLGDVVCGGFASPLQHADRALIVTANDFDSIFAMNRIVAAIHTKSKNYGVRLGGVIANRSAGTDEIDRFNAAVGLRRLAHFPDLDVVRRSRLKKATLFEMEPTPELKAVTDEYMQLAETLWAGADPCEAVPMKDRDLFEFLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: RR8_CRUWA
Sequence: MGKDTIADIITSIRNADMNRKGTVRIGSTNITESIVKILLREGFIENVRKHRENNQYFLILTLRHRRNKKESYKTILNLKRISRPGLRIYSNSQRIPRILGGIGIVILSTSQGIMTDREARLKRIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ODP2_STAAR
Sequence: MAFEFRLPDIGEGIHEGEIVKWFVKAGDTIEEDDVLAEVQNDKSVVEIPSPVSGTVEEVMVEEGTVAVVGDVIVKIDAPDAEDMQFKGHDDDSSSKEEPAKEEAPAEQAPVATQTEEVDENRTVKAMPSVRKYAREKGVNIKAVSGSGKNGRITKEDVDAYLNGGAPTASNESAASATNEEVAETPAAPAAVSLEGDFPETTEKIPAMRRAIAKAMVNSKHTAPHVTLMDEIDVQALWDHRKKFKEIAAEQGTKLTFLPYVVKALVSALKKYPALNTSFNEEAGEIVHKHYWNIGIAADTDRGLLVPVVKHADRKSIFQISDEINELAVKARDGKLTADEMKGATCTISNIGSAGGQWFTPVINHPEVAILGIGRIAQKPIVKDGEIVAAPVLALSLSFDHRQIDGATGQNAMNHIKRLLNNPELLLMEG
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: GOSR1_PONAB
Sequence: MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMSIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH
What is the function of this protein?
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport.  It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.  May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14).  Participates in docking and fusion stage of ER to cis-Golgi transport.  Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi (By similarity).
What are the official names of this protein?
Golgi SNAP receptor complex member 1, 28 kDa Golgi SNARE protein, 28 kDa cis-Golgi SNARE p28.
What is the protein family that this protein belongs to?
Belongs to the GOSR1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein. Note=Localizes throughout the Golgi apparatus, with lowest levels in the trans-Golgi network. Enriched on vesicular components at the terminal rims of the Golgi.
Protein: NEU2_LOXAF
Sequence: AMSDMELRQCLPCGPGGKGRCFGPSICCGEELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCYEESCVTEPECREGAGIH
What is the function of this protein?
Neurophysin 2 specifically binds vasopressin.
What are the official names of this protein?
Neurophysin 2, E-NP, Neurophysin-II.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y423_PSEAE
Sequence: MLKKTLAALALGSALFTAGQAMAADYKIDKEGQHAFIEFRIKHLGYSWLYGRFNDFDGSFTFDEKNPSADKVKVTINTNSVDTNHAERDKHLRSGDFLNVSKNPTATFESTEVKANGDSADITGNLTLNGVTKPVTIKAKLIGQGDDPWGGYRAGFEGSATLKLKDFGIKMDLGPASQEVELLLSVEGIRQ
What are the official names of this protein?
UPF0312 protein PA0423.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: UPPP_ELUMP
Sequence: MTSVNAVLLGLVQAAGEFLPISSSAHLVLMPWLLGMEYQGLTYDIFLHLATLIAVLIYFRKEWFTIIKDGLTKPKTEEGKILWLLVLGTIPAAICGVLFEDWIETVFRSPFVIAAALIVFAVILHLADKRAGQKDVALNVKTVLIIGCAQALALMPGVSRSGITITAALFLGFSRAESAKISFLLSTPIIAGAAVLKLKDINPADINAAFIAGFLTAAIFGWLFIKFLMNYVQKHNFNIFVVYRIALGVIIIITALMK
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DADA_PSEPW
Sequence: MRVLVLGSGVIGTASAYYLARQGFEVTVVDRQPAVAMETSFANAGQISPGYASPWAAPGVPLKAIKWLLERHAPLAIKLTGDVDQYLWMAQMLRNCTASRYAVNKERMVRLSEYSRDCLDELRAETGIAYESRTLGTTQLFRTQAQLDAAAKDIAVLEQSGVPYELLDRDGIARVEPALAGVKDILAGALRLPNDQTGDCQLFTTKLAEMALKLGVEFRFGQDIQRLDFAGDRINGVWVDGKLETADRYVLALGSYSPQMLKPLGIKAPVYPLKGYSLTVPITNADMAPTSTILDETYKVAITRFDNRIRVGGMAEIAGFDLSLNPRRRETLEMIVNDLYPRGGDLSQASFWTGLRPATPDGTPIVGATAFRNLFLNTGHGTLGWTMACGSGRLLADLIARKKPQISAEGLDISRYGKTREVAKQGHTAPVHQ
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: CLPS_PARXL
Sequence: MAIIPDKQDGTVLERQEKKLKPPSMYKVVLLNDDFTPMEFVVMIVQEYFNKDRETATQVMLKVHREGRGVCGVYTRDIASTKVEQVVTHARQAGHPLQCVMEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: MENH_SALCH
Sequence: MMLHAQHMPGQPGAPSLVFLHGFSGDCREWQPVGEQFHGCSRLYIDLPGHGGSAAIPVGRFADVIRLLRATLISYNILKFWLVGYSLGGRVAMMAACQGIPGLCGLVVEGGHPGLQNEQARAERRLSDGRWAERFRREPLTEVFHDWYQQPVFASLTAQQRQALTALRSQNNGETLAAMLEATSLAAQPDLREALNALAFPFYYLCGERDSKFRALAQEVAATCHVIRNAGHNAHRENPAGVVDSLAQILRL
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: NRDR_ECO8A
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MANA_PODAN
Sequence: MKGLFAFGLGLLSLVNALPQAQGGGAAASAKVSGTRFVIDGKTGYFAGTNSYWIGFLTNNRDVDTTLDHIASSGLKILRVWGFNDVNNQPSGNTVWFQRLASSGSQINTGPNGLQRLDYLVRSAETRGIKLIIALVNYWDDFGGMKAYVNAFGGTKESWYTNARAQEQYKRYIQAVVSRYVNSPAIFAWELANEPRCKGCNTNVIFNWATQISDYIRSLDKDHLITLGDEGFGLPGQTTYPYQYGEGTDFVKNLQIKNLDFGTFHMYPGHWGVPTSFGPGWIKDHAAACRAAGKPCLLEEYGYESDRCNVQKGWQQASRELSRDGMSGDLFWQWGDQLSTGQTHNDGFTIYYGSSLATCLVTDHVRAINALPA
What is the function of this protein?
Endo-1,4-mannanase that catalyzes the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans and heteromannans.  It is a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.  Hydrolyzes structurally different mannan polysaccharides, such as galactomannans, glucomannans, and beta-1,4-mannans from different sources, yielding principally mannobiose (PubMed:21037302).  Also has transglycosylation activity (PubMed:23558681).
What are the official names of this protein?
Mannan endo-1,4-beta-mannosidase A, Endo-beta-1,4-mannanase A, Man5A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.