PharMolix/UniProtQA huggingface dataset:
Protein: H2A_BOTFB
Sequence: MTGGKSAGGKAGTTKNAQSRSSKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKTAKTAGGKPASQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: O16K0_CONTE
Sequence: MKLTCMMIVAVLFLTAWTFATADDSGNGLENLFSNAHHQMKNPEASKLNKRWCKQSGEMCNLLDQNCCDGYCIVLVCT
What is the function of this protein?
Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process.  Binding of this toxin is strongly calcium-dependent but not voltage-dependent.  The binding site is most likely on the extracellular side of the sodium channel.  Binds receptor sites on both mollusk and rat central nervous system, but despite its high affinity binding to rat sodium channel, it has no functional effect in vivo and in vitro on it.  Has also no effect on Gambusia fish.  Is important in mollusk for the paralysis of the prey.  Upon injection of the peptide, a subordinate lobster assumes an exaggerated dominant posture (of a 'King-Kong' lobster!).
What are the official names of this protein?
Delta-conotoxin TxVIA, Conotoxin King-Kong 0, KK-0, Conotoxin tx6a, TxIA, TxMKLT1-0112.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CSGF_SHIFL
Sequence: MRVKHAVVLLMLISPLSWAGTMTFQFRNPNFGGNPNNGAFLLNSAQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIVDIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF
What is the function of this protein?
May be involved in the biogenesis of curli organelles.
What are the official names of this protein?
Curli production assembly/transport component CsgF.
Protein: SHLB1_MOUSE
Sequence: MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSGTPVPYALSNAIGPSAQASTGSLVITCPSNLNDLKESSNNRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN
What is the function of this protein?
May be required for normal outer mitochondrial membrane dynamics.  Required for coatomer-mediated retrograde transport in certain cells (PubMed:17086176).  May recruit other proteins to membranes with high curvature.  May promote membrane fusion (By similarity).  Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PubMed:16227588).  Isoform 1 acts proapoptotic in fibroblasts (PubMed:24523556).  Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy.  Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2).  Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation.  Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (By similarity).  Isoform 2 acts antiapoptotic in neuronal cells; involved in maintenance of mitochondrial morphology and promotes neuronal viability (PubMed:24523556).
What are the official names of this protein?
Endophilin-B1, SH3 domain-containing GRB2-like protein B1.
What is the protein family that this protein belongs to?
Belongs to the endophilin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane. Midbody. Note=Association with the Golgi apparatus depends on the cell type. Following starvation colocalizes with ATG5 and LC3 autophagy-related protein(s)on autophagosomal membranes.
Protein: RS9_CHRVO
Sequence: MNGKYYYGTGRRKSSVARVFMQKGSGQIIVNGKPVDEYFARETGRMVIRQPLALTENLESFDIKVNVVGGGETGQAGAIRHGITRALIDFDAALKSALSAAGYVTRDAREVERKKVGLRKARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CARB_STRSV
Sequence: MPKRKDIQKIMVIGSGPIVIGQAAEFDYAGTQACLSLKEEGYSVVLVNSNPATIMTDKEIADRVYIEPITLEFVARILRKERPDALLPTLGGQTGLNMAMELSKSGLLEELGVELLGTKLSAIDQAEDRDLFKQLMEELGQPIPESEIVNTVDEALEFAAGIGYPVIVRPAFTLGGTGGGICSNEEELQEIAENGLKLSPVTQCLIERSIAGFKEIEYEVMRDGADNALVVCNMENFDPVGIHTGDSIVFAPSQTISDYEYQMLRDASLKIIRALKIEGGCNVQLALDPHSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIINPVTGSTYAMFEPALDYVVAKIPRFPFDKFEQGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEVCVDHNELPALSQVSDDELMRKIVKAQDDRLFYISEAIRRGYSPDEIAELTKIDVFFLDKLLHIYEIEQELASHIGDSYVLKKAKQNGFADTKIASLWDMTAEQVRRIRQEQKIVPVYKMVDTCAAEFESATPYFYSTYGFENESVKSSKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIELEQPKGVIVQFGGQTAINLAEPLSKAGVKILGTQVADLDRAEDRDLFEQALKELDIPQPPGQTATNEEEAVEAARKIGFPVLVRPSYVLGGRAMEIVENEADLRSYMRTAVKASPDHPVLVDSYIVGDECEVDAISDGRQVLIPGIMEHIERAGVHSGDSMAAYPPQTLSQKVKDTIADYTKRLALGLNCIGMMNIQFVIKDEQVYVIEVNPRASRTVPFLSKVTDIPMAQVATRLILGETLAELGYEDGLYPESSMVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSDRTLEKALYKAFEASYLHLPNFGNIVFTIAGDSKEEALQLAQRFANIGYGIWATKGTASYFENHGLHVRLVEKIGSDDDKDIPAYIRKGKVQAIINTVGTKRTADKHGQIIRSSAIEHGVPLFTALDTADAMLKVLESRSFTTEAI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: KTHY_LATSS
Sequence: MVGKLITFEGPDGAGKTSALEAVVARLQKEVSQEIVVTREPGGNPISEQIRQIILDVKNTAMDDRTEALLYAAARRQHIVEKIQPALAADKLVICDRFVDSSIAYQGAGRGIGEEAVAQMNLFATDGLTPDLTLYLDVPSEVGLARIKQHRQNQYDRLDQEKLAFHQKVRQSYLKLAQAHPDRIKTIDASQPLEAVVTQCLQVIAQANLHLFEV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ELP3_CHICK
Sequence: MGQKRKDLSHAELMMMTIADIIKQLIEAHEQGKDVNLNKLKTKTSAKYGLSAQPRLVDIIAAVPPQHRKALVPKLKAKPIRTASGIAVVAVMCKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALPEDYRDYFIRNLHDALSGHTSNNVAEAVKYSERSLTKCVGITIETRPDYCLKRHLSDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDAGFKVVAHMMPDLPNMGLERDTDQFVEFFENPAFRPDGMKLYPTLVIRGTGLYELWKTGRYKSYPPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTQCRDVRTREVGIQEIHHKVRPYQIELIRRDYVANGGWETFLSYEDPEQDILVGLLRLRKCSEESFRPELKGGVSIVRELHVYGSVVPVSSRDPSKFQHQGFGMLLMEEAERIAKEEHGSWKIAVISGVGTRNYYRKIGYELEGPYMVKRLQ
What is the function of this protein?
Catalytic tRNA acetyltransferase subunit of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity).  In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).
What are the official names of this protein?
Elongator complex protein 3, tRNA uridine(34) acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ELP3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: URE1_BURM9
Sequence: MTLRLSRRAYAEMYGPTTGDRIRLADTELLIEVERDHTLYGEEVKFGGGKVIRDGMGQSQLPAADVADTVITNAVILDHWGIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEIIAGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGTGPATGTNATTCTPGPWHMERMLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDTDTQVAIHTDTLNEAGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEANVLPSSTNPTRPYTINTLDEHLDMLMVCHHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSSDSQAMGRVGEVIIRTWQTAHKMKVQRGALAGDGARNDNFRAKRYVAKYTINPALTHGIAHEVGSIEPGKWADLVLWEPAFFGVKPAMIVKGGMIAVAQMGDPNASIPTPQPVHYREMFATRGGALARTSLTFVSQLALDAGIGARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAIRVDPETYDVVADGALLTCEPAAVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECR_CAVPO
Sequence: HSDGTFTSELSRLRDSARLQRLLQGLV
What is the function of this protein?
Hormone involved in different processes, such as regulation of the pH of the duodenal content, food intake and water homeostasis.  Exerts its biological effects by binding to secretin receptor (SCTR), a G-protein coupled receptor expressed in the basolateral domain of several cells.  Acts as a key gastrointestinal hormone by regulating the pH of the duodenal content.  Secreted by S cells of the duodenum in the crypts of Lieberkuehn and regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate (NaHCO(3)) from the ductal cells of the pancreas (By similarity).  Production of bicarbonate is essential to neutralize the pH and ensure no damage is done to the small intestine by the gastric acid.  In addition to regulating the pH of the duodenal content, plays a central role in diet induced thermogenesis: acts as a non-sympathetic brown fat (BAT) activator mediating prandial thermogenesis, which consequentially induces satiation.  Mechanistically, secretin released by the gut after a meal binds to secretin receptor (SCTR) in brown adipocytes, activating brown fat thermogenesis by stimulating lipolysis, which is sensed in the brain and promotes satiation.  Also able to stimulate lipolysis in white adipocytes (By similarity).  Also plays an important role in cellular osmoregulation: released into the systemic circulation in response to hyperosmolality and acts at different levels in the hypothalamus, pituitary and kidney to regulate water homeostasis (By similarity).  Also plays a role in the central nervous system, possibly by acting as a neuropeptide hormone: required for hippocampal synaptic function and neural progenitor cells maintenance (By similarity).
What are the official names of this protein?
Secretin.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATG2_ASPOR
Sequence: MAYFLPSFFQKRLLRYALSRLELVDTEALDLDSLGIRWGQRSTVELRDIGLRLETRRAETHDATTDQKTSGRVDPGSGDEPILPNPTDLAESFLQAEPKEEKEELQAAISSQSQVLQHTSTSSSDDEEELGLGNETVSLPSFVAAFLKGVVDRLQVQVDDISIRVDVETKQEGSSKRHPEEKPDLITGLLSVRQVSMGAVSTHSESGEASSSERRRLVSLSDINLALISEPVVFSNYSRFAAPASPSTPVQPKSSRPPSRAQSPSPETSSESSLALAMTRSTIFEPPQDLTRQELEEQHTPRLEGSVYTYDGRFSDADTEDGKRSYGSLEDSRQFEDDEKLLDNPAYLDSVIDYQFQDDDPERLDDMQTRVDGLFRRSRDTPRSQSPEHTAELTDQNSHPEGALIPLNDRHELEVARLPSHQHFLEAPEAITEPGSSGLTPEKDFRPGYKQQLPLVCAPSSEPDSSGSASESFKESELSESRLFSNEEAQSMYMSAISQGSTSHSFMPNIPGAWDSPESTYVRDTGFHETPTAMEQDAYSEQDETITTPKLTAQEGIYLSHASSIDNLQKTTTGTTGRESIQTSPGFNRLTDVAKRFVSVDKVLIWIPSVNHEKVPGDSQSASHQEMSSDGLKDSTAYLQDSVIDDDLLASRIHGFPGPRSGANDPSSPHEGVDHKASGYQEKTKHDAGFSSERDEATVEIHSAEVQFDIAIGWLVIKIGKRIVNAFGHGDGEPPKKHNSESKAPEQVQPKESFGLILNKFSIKFVEHVPGHANPFGESRQYSPTFFGLMHEDIVLQTTASGLKAHFSSTNDQTKLRLDITKFTLGVASEDLISFNQDLKMRESMRDVLSPMHGDISLSMSKSLESARIHVTTLPLHLNLNIQRLEEVVGWIGGLSTILELGSSISSASGAKTPKKDPPKRPRGVHFEAPPSPEKLPQDTSLPWKVNARIGGVALNIVGESHYLKLRTTAVKVVSRFEGVGVQIDKAKLSGPLPLDDSKDAPAKINLSNIRIEYLFAPKEVDLDRLLSLITPSKDKYDEDDDIMLDTLFRQRRQGSVLRTTIAGADIMISRITDFDSLPQLGDELSRLSNVAKYLPEDDRPGLLTLNLIRDFEARVNVGGKVGDITARLKNAEVAYISIPSLVAAQVGSATVLRNGTEELLGEALPLSAEQRSGQIPHPMLMARFIADEMEPTIKVKMHNLRAEYTVPAAIAFLGLNESSTTSDFAANMAQSIGNLAELQPSKESQSAIKPGSPKSPVRPTILALALRDCVIGLNPRGSEAKGLVVLTNANFSGAMDDGASSEATLDLRKASIMIIDDVRNMGSTDDSHRRNSTAPPTNQVQSFIDMGFVTVSSISSATASVKLLRSGEDGTQSLDVELRDDLLILETCADSTQTLISIVNGLQPPTPPSVTKKYRTEVLPLQDMLASFSGDAFALNSSSSLEGVSETAGDSAENIQDKEGHIEDEVEYVSDFYPAKPTSGGGSLHEAMTASGSNELLDSFHSQYYVSSSISDLEFRDDHFATQSAVGGTAHRWDSTENTYGLSDDTKLQKSPLRIRVRDAHVIWNLFDGYDWQRTRDTISKAVKDVERKATDRRARANRASPSFDEDEESVIGDCLFNSIYIGIPANKDPRELRSDINRNIDDLVSETGSYATTTTVTGATVRQSQSPSFRKKLRLSRSKYHKMTFELKGICADLVVFPPDSGETQSSLDVRVNDLEIFDHVPTSTWKKFATYMHEVGEKESGTSMVHLEILTVRPVPELAASEIVLKATLLPLRLHVDQDALDFLCRFFEFRDDSAPASSAPQDIPFLQRVEINAVPVKLDFKPKRVDYTGLRSGRTTEFMNFFVLDGADMVMRHVIIYGVSGFDKLGQTLNDIWMPDIKRNQLPGVLAGLAPIRSLVNVGGGVKDLVVVPMREYRKDGRIVRSIQKGALAFAKTTSNELVKLGAKLAIGTQTVLQGAEDLLTSPNTQLAGAEEELGDEEEAKKISLYADQPVGVVQGLRGAFRGLERDLLLTRDAIVAVPGEVVESGSAKAAAKAVWKRAPTVILRPAIGVSKAVGQTLLGAGNTLDPSNRRKMEDKYKRH
What is the function of this protein?
Lipid transfer protein required for autophagosome completion and peroxisome degradation.  Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion.  Atg2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region.  The latter binding is assisted by an atg18-PtdIns3P interaction.  Atg2 then extracts phospholipids from the membrane source using its NR and transfers them to atg9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
What are the official names of this protein?
Autophagy-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATG2 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: IHFB_KLEP3
Sequence: MTKSELIERLASQQSHIPAKAVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYEE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PSBA_CHLRE
Sequence: MTAILERRENSSLWARFCEWITSTENRLYIGWFGVIMIPCLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIITGAVIPTSNAIGLHFYPIWEAASLDEWLYNGGPYQLIVCHFLLGVYCYMGREWELSFRLGMRPWIAVAYSAPVAAASAVFLVYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGLSTMAFNLNGFNFNQSVVDSQGRVLNTWADIINRANLGMEVMHERNAHNFPLDLASTNSSSNN
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, 32 kDa thylakoid membrane protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RSMA_CAMJE
Sequence: MVKAKKQYGQNFLIDKSVLAKIIQAIPKEMNNIIEIGPGLGDLTQELLKISQVKAYEIDNDLIPILKKKFQKELECGKFNLIHQDASEAFNPSLDEKPYFLVANLPYYVASHIILKALEDKNCLGLIVMAQREMAEKFCAKEGNSEFSSLGVLSAMICERKILFDVDPQCFNPPPKVMSAVMSLIKTKDFDELCEIENFKNFLKDCFKAPRKQLLGNLKTYKAKVLEVLSTLGLKENIRPHEICVDLYLKIYDKLKDEYGRKQRDK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_PHEZH
Sequence: MPTVNQLIRKPRQTKPARNKVPALKGCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTTGIEAVCYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHILRGVLDTQGVKDRKQRRSLYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: EX7L_BRADU
Sequence: MPNRLPMPPAEPLLNAPEFTVSELSQSLKRTVEDAFGHVRVRGEISGFRGAHSSGHCYFALKDESAKIEAVIWKGVHGRMRFKPQEGLEVIATGKLTTYPGSSKYQIVIEALEPAGIGALMALMEERKKKLAAEGLFDEARKQLLPWLPEVIGVVTSPTGAVIRDILHRLEDRFPRHVLVWPVKVQGEGSAEQVAAAIRGFNALPEGGKIPRPDVLIVARGGGSLEDLWSFNEEIVVRAAAESMIPLISAVGHETDITLIDFVADKRAPTPTAAAEMAVPVRSDLFVEVADLARRTRAYWQRAHESRRSELRAAARALPAAGDLLAIPRQRLDSAGAALPRGLKANTHAHFRRFTAAGAKLTLRVLHGQIAQADHRLTVCGERLGLSARSLLRQRRDRFAGLEVRLRASKLSNAQAQRNAIARQRERTHRLAERANRALVTLLQRLDARVEASGKLLSALSYRGVLARGFALVRDEAGHPLHSADSVGPGARVEIEFADGRVGATTDADRPAPPAKRAQQPKPAAQETKPAPKRVGKPVDQGSLF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPCA_RHOOP
Sequence: MRTGQQYLESLRDGRQVYVGGELIDDVTTHPKTSGYAKAIAEYYDLHLDPEHQDVLTFVDDDGVRKSMHWFLPRSKADAARRRAYHEFWFRHFQGGIFTRPPAGMHVVMYAQIDDPEPWGDNAVVAGGRTISFADNIRSQWQRVTTDDVALSPMFVDVQFDRGRDDALVETPMLSIVEQNDQGIVVRGWKAMGTSLPFVNELLVGNLWRPGQTSDQTVYAIVPVNTPGLSLVCRQSNATPDADPYDHPLSTIGDELDGMAYFDDVFIPWENVQHIGNPDHAKWYPQRQFDWVHIETQIRHAVHAELIVGLALLLTNALGTNNNPIVQSQLADLVRFRETCKAFAIAAEETGFTTAGGLFKPNNIYVDLGRAHYLENIHNAVNQLIEFCGRGVVMSPTKADFDHPFLGPKLEEALRGTSISARDRVSIFRQISERYLTQWGARHEMFEKFNGTPLYLVRLLTMQRTEYQVDGPLTDLARQVLGFGDTEALAARAAEVEKNSNWASVAYQPEYAREQDVRDGYYKETEKV
What is the function of this protein?
Involved in the degradation of para-nitrophenol (4-NP).  Catalyzes both the initial hydroxylation of 4-NP to produce 4-nitrocatechol (4-NCA) and the subsequent oxidative release of the nitro group from 4-NCA to produce 2-hydroxy-1,4-benzoquinone.  It can also use 4-nitroresorcinol as substrate with a rate of nitrite release similar to that observed with the two physiological substrates, 4-PN and 4-NCA.
What are the official names of this protein?
4-nitrophenol 4-monooxygenase/4-nitrocatechol 2-monooxygenase, oxygenase component, 4-NP/4-NCA monooxygenase, PNP monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the FADH(2)-utilizing monooxygenase family.
Protein: RSSA_YARLI
Sequence: MSAPIFDPTPEDIQNLLAAQTHIGSKNVQVQNIPYVFKQRADGVNIINVGKTWEKIQLAARIIAAVPNPADVVAISARTYGQRAVLKFANHCGATAIAGRFTPGSFTNYITRSFKEPRLLIVTDPRTDHQAIKEASYVNIPVIALVDTDSPVEFVDVAIPCNNKGRHSVGLVWWMISREVLRLRGALEDRNTEWSVMPDLYFYRDPEEPENTEEAAEEAATEEVVETAAAEAAAATNADNWDVAPDAGAGAADWAATDDWSESAPAPVAA
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P26_BNYVS
Sequence: MDIDHCMPVFDMAYSDDNHLPYYIQRSTHHVVRDVDYTGFICYPLQVDLNDNVEVGADIYHMKIKTMRFNVDIYNNDVATKFPGWVRFIVFCTPPVSSWVNDGCSSLFSPFVGVNSFIDPKLLKRDGHGITVLHDGIYCLCHQEHFTRSFEFNFRGPGNYTLTSDVCWSPATNVDSIYVACVASWCGDSAFMLQSDSVSWVHKRFWQRPVLEFGQCLDDLPDHDNDCG
What is the function of this protein?
Probably influences symptom severity in a synergistic fashion with P25.
What are the official names of this protein?
Protein P26, 26kDa protein.
What is the protein family that this protein belongs to?
Belongs to the benyvirus P25 protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: B1H_LOXLA
Sequence: MLLSAVISFIGFAAFLQEANGHVVERADSRKPIWDIAHMVNDLDLVDEYLGDGANALEADLAFTSDGTADEMYHGVPCDCFRSCTRSEKFSTYMDYIRRITTPGSSNFRPQMLLLIIDLKLKGIEPNVAYAAGKSTAKKLLSSYWQDGKSGARAYIVLSLETITRQDFISGFKDAIDASGHTELYEKIGWDFSGNEDLGEIRRIYQKYGIDDHIWQGDGITNCWVRDDDRLKEAIKKKNDPNYKYTKKVYTWSIDKNASIRNALRLGVDAIMTNYPEDVKDILQESEFSGYLRMATYDDNPWVK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) with low activity (PubMed:19249326).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces hemolysis, dermonecrosis, and edema (PubMed:19249326).  Also induces platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LlSicTox-betaIA1, LlH10, H10, Phospholipase D, PLD, SMase II, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily. Class IIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.