PharMolix/UniProtQA huggingface dataset:
Protein: AROK_PHOPR
Sequence: MLTMAEKRNIFLVGPMGAGKSTIGRHLAQQLHMEFFDSDTVIEDRTGADISWVFDVEGEEGFRVREEGVIDDLTQEQGIVLATGGGSVVSKENRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQTDAPREVLEALAAERNPMYEEVSDYVVRTDDQSAKVVANQIINMLEER
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHA1_STAAT
Sequence: MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit A1, Mnh complex subunit A1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARAG_AZOBR
Sequence: MTTQTMTAVSGNDGDTGGDAAESPPGGPLLALDGITVTFPGVRALDAVSLSVRAGEVHGLMGENGAGKSTLLKVLSGVNQPQAGTLTLNGTEQRFASTRAALEAGIAIIYQELHLVPELTVAENLMLGQLPSRLGVVDERTLAARALDALERLGEHIDPGIPVKYLSIGQRQMIEIGKALMRDARVIAFDEPTSSLSARETTQLFRIIRALRAEGRAIIYVTHRMEEVYELCDRVTVFRDGRRIDTFDSVTDLDRDRLIGCMVGRSIEDVYGYRPRAAGDVLIEAKGLAGPGLSEPVSFTARRGEIVGFFGLVGAGRSELMKLLYGAARPSAGHVELNGKRVAFGSPRDAVRAGLALCPEDRKQEGIVAIASVADNLNISARRHFSPARVLLDGRRERELAQRYIERLAIKTRDGDTPIGALSGGNQQKVVLARWLAERIDVFLMDEPTRGIDVGARAEIYNLFYELAEAGRTVILVSSDLAEVIGVSDRIIVMKEGRIAGEVAKAHATPDALIKLALPR
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in L-arabinose import.  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UVRC_UREP2
Sequence: MNDLLKNKLKLIPHKPGCYLWKDQFNQIIYIGKAKDLYNRTHSYFNGCKDNKTSKLVNNINDLEYIVVNNVNEALILENNLIKTHLPKYNILLKDGSNYPYIMITNEQYPRLKYVRTYDKNKGIYFGPLADSTNKYQLFNLLNSIFPFNKCNHQPYKKCIYYDLHQCINQVQQSTYQEAISEVKEIFKGNLDHILMILQTKEQHAVTKLDFENAQKYAEQQKALTSIINSGLVQLDNNESFDIIGFYEKNNYLVIIIFNYVKGKLLNKSADTFAIYDYEINELITSFLMQYYSQNKISSKIIVSLDDDNLLALSQRFHTKFINAQTKFHKRILKLALDNAILYFESNIKNVINKQNELDDALNQLKQILKLPDLNIIECFDNSNINLSLPIAGMIVYQNGKLNNKLNRKYNLMTTKNASDYHFMIEVITRRYQRLVSQHQKLPNLIVVDGGKLQVNAALYALAQLQINIPLIGLKKDQKHKTDAIVLTNGDEIVLDRKSILYKFLANMQNDVHNYAISFLRDKHTKSIFNSLLDNVQGLGKKRFNELLKYYDSINDLKSASDQELLQFLPKNVLVNLREKLNKI
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROBI_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGITTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVCGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PAOX_BOVIN
Sequence: MQSGGRQAEAPGRGPRVLVVGGGIAGLGAAQRLCRHPAFSHLRVLEATARAGGRIRSEHSFGGVVEVGAHWIHGPSQGNPVFQLAAKYGLLGEKALSEENQLIETGGHVGLPSVSYASSGVSVSLELVAEMASLFYSLIDQTREFLQAAETTPPSVGEYLKEKIRQHMAGWTEDEETKKLKLAILKNLFNVECCVSGTHSMDLVALAPFGEYTVLPGLDCTFPEGYQGLTDCIMASLPKDVMVFDKPVKTIHWNGSFREASAPGETFPVLVECEDGDCFPAHHVVVTVPLGFFKKHLDTFFEPPLPTEKVEAIRKIGFGTNNKIFLEFEEPFWEPDCQHIQVVWEDMSPLEDTAPELQDAWFKKLIGFWVLPPFQASHVLCGFIAGLESEFMETLSDEDVLRSLTQVLRRVTGNPQLPAPRSMLRSCWHSAPYTRGSYSYVAVGSSGDDMDRLAQPLPSDGKGAQLQVLFAGEATHRTFYSTTHGALLSGWREADRLMTLWDPQAQWPEPRL
What is the function of this protein?
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion.  Can also oxidize N(1)-acetylspermidine to putrescine.  Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine.  Does not oxidize spermidine.  Plays an important role in the regulation of polyamine intracellular concentration.
What are the official names of this protein?
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidase.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Peroxisome. Cytoplasm.
Protein: SERA_METJA
Sequence: MVKILVTDPLHEDAIKILEEVGEVEVATGLTKEELLEKIKDADVLVVRSGTKVTRDVIEKAEKLKVIGRAGVGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWDRKRFKGIELYGKTLGVIGLGRIGQQVVKRAKAFGMNIIGYDPYIPKEVAESMGVELVDDINELCKRADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYEALKEGKIRAAALDVFEEEPPKDNPLLTLDNVIGTPHQGASTEEAQKAAGTIVAEQIKKVLRGELAENVVNMPNIPQEKLGKLKPYMLLAEMLGNIVMQVLDGSVNRVELIYSGELAKEKTDLIKRAFLKGLLSPILLAGINLVNAPIIAKNRNINVVESSTSEEKYGNAIKITAESDKKKFSIVGAIINNKPVILEVDGYEVSFIPEGVLAIIKHIDRPGTIGRVCITLGDYGINIASMQVGRKEPGGESVMLLNLDHTVPEEVIEKIKEIPNIKDVAVINL
What are the official names of this protein?
D-3-phosphoglycerate dehydrogenase, PGDH.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: Y8158_DICDI
Sequence: MQDTLITATVNNCNINNNNNNNNNNNNNNNSKNSKNFNTSDLYNSVSDYKVESITEFQINQINMEQQSTKKRSASTLSAPPSTSSSGEEDNIINKNNKNNNNNNNSTNNNNSSKKKKRISNETNDDDKPKRPRKNEAVCTFCEKPGELLMCDGLCLRSFHISCLKARNLYNPSSSSISPVTTIDGTVRWECNDCVSSQNSCFSCKKRGIIGIDLMKCKVHQCGKFYHYKCVADYKLAKLINTKTPRFNCPLHYCSVCEVSGDGKQSVHCFRCPTAYHVICMQPGVKMLTKTRETRKTGLVLCPKHIGEQNPHDHDQIHNHTHTHTHTSQSNISSTSSSSVPSLIISSTSAIGSINTSGEIFQSSPPSSLTRKSSIPTSIITKSINNNNNNNNNNNNNNNNNLNINNNLNINNNNNNNNNFKPIQNNIESNINPLHYLMYSTSPITSPTTLSIPTSPLSSPSYSPNYTANFKPNSFDVNQQQQQQQQQQQPIKIPKYINNFNAIKNQQKLLNTNNNTNNNIYNNINNSYNRNNQNNNLNINNINNNNNNNNDGEYDDLYDDISQYASSLMSIKDQTVSVSSFSSPSSSSSSSSRENSFSSNINNINNKTDESTIIIPESFEKMHNSDRVACLKKSLQQQMQQQQQQQQQEQLVVQPKKLDEGKLIEQFFQFSKSKNFHSQNCKNSFTPY
What are the official names of this protein?
PHD finger-containing protein DDB_G0268158.
Protein: RECA_CORU7
Sequence: MAPKKKATTAAQKDRSKALDLAMAQIEKDFGKGAIMRLGDENRPPISAIPSGNIAINVALGIGGFPRGRVVEIYGPESSGKTTVALHAIAEAQKGGGIAAFIDAEHALDPEYAKALGVDTDALLVSQPDTGEQALEIADMLVRSGAIDMVVIDSVAALTPKAEIDGEMGDSHVGLQARLMSQALRKMTSALYQTGTTAIFINQLREKIGVMFGSPETTTGGKALKFYASVRCDIRRIQALKDGQDVVGNRTRLKIVKNKVSPPFKIAEFDILYGEGISREGSILDLGVDAGIIKKSGSWFTYEGEQLGQGKEKARDFLKSNPELAEQLDDRIMQELKVGPYAKAKDEPIADEDQPIDVVPNFDDQDVEPQN
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTC_CLOPE
Sequence: MNEKDLKLMVEQLVSQMVGQVDMQSVEKVVKEVSKNQSQVESDEFIPDITEIDIKKQLLVDNPADREAYLEMKAKTPARLGSGRAGARYKTITALRMRADHAAAQDSVFSDVSEEFIKKNNFIPVKTMCTDKDEYVTRPDLGRRFSPETTEIIKEKCDKNPKVQIMVGDGLSSAAIEANVEDILPSIEQGLKMYGLNVGPILFVKYCRVPAMDAVGEATGADVVCLLVGERPGLVTAESMSAYIAYKPKVGMPEAKRTVISNIHKGGTTAVEAGAHIAELIKTMLDKKASGIDLK
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: CH60_XANC8
Sequence: MAAKDIRFGEDARTRMVRGVNVLANAVKATLGPKGRNVVLEKSFGAPTITKDGVSVAKEIELADKFENMGAQMVKEVASKTNDNAGDGTTTATVLAQALIREGAKAVAAGMNPMDLKRGIDQAVKAAVIELKNISKPTTDDKAIAQVGTISANSDESIGNIIAEAMQKVGKEGVITVEEGSGLENELDVVEGMQFDRGYLSPYFINNQQSQSADLDDPFILLHDKKISNVRDLLPVLEGVAKAGKPLLIVAEEVEGEALATLVVNTIRGIVKVVAVKAPGFGDRRKAMLEDMAVLTGGTVISEEVGLALEKATIKDLGRAKKVQVSKENTTIIDGAGDSATIEARVGQIKTQIEDTSSDYDREKLQERVAKLAGGVAVIKVGASTEIEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRALVAVGNLTGANEDQTHGIQIALRAMEAPLREIVANAGEEPSVILNKVKEGTGNYGYNAANGEFGDMVEFGILDPTKVTRSALQNAASIAGLMITTEAMVADAPKKDEPAMPAGGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y656_FINM2
Sequence: MESLGIGFSNLVNSNRIIAIVSPETNPIKRIVQKAKEDNNLIDVTFGRKTRSVIIMDSSHVVLSCLQPETLQMRLDKSNNKED
What are the official names of this protein?
Putative regulatory protein FMG_0656.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: CAVN4_BOVIN
Sequence: MEHNGSASNADKIHQNRLSNVTEDEDQDAALTIVTVLDKVAAIVDSVQASQKRIEERHRVMENAIKSVQIDLLKFSQSHSNTGYVINKLFEKTRKVSAHIKDVKARVEKQQTHVKKVEAKQEEIMKKNKFRVVIFQEEVQCPTSLSVVKDRSLTESPEEVDEIFDTPVDLSSDEEYFVEESRSARLKKSGKERIDNIKKAFSKENMQKTRQNFDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLKQSGERFKKSISNAAPSREAFKMRSLRKTKDRAVAEGPEEVREMGVDIIARGEALGPISELYPEALSETDPEEASATHPPQEGGEVSTPEPLKVTFKPQVKVEDDESLLLDLKQ
What is the function of this protein?
Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation.  Facilitates the recruitment of MAPK1/3 to caveolae within cardiomyocytes and regulates alpha-1 adrenergic receptor-induced hypertrophic responses in cardiomyocytes through MAPK1/3 activation.  Contributes to proper membrane localization and stabilization of caveolin-3 (CAV3) in cardiomyocytes.  Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway.
What are the official names of this protein?
Caveolae-associated protein 4, Muscle-related coiled-coil protein, Muscle-restricted coiled-coil protein.
What is the protein family that this protein belongs to?
Belongs to the CAVIN family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere. Cytoplasm. Cytoplasm, cytosol. Cell membrane, sarcolemma. Membrane, caveola. Note=In cardiomyocytes, accumulates in the Z-line of the sarcomere. In vascular smooth muscle cells, detected diffusely throughout the cytoplasm. Localizes in the caveolae in a caveolin-dependent manner.
Protein: SYDND_ACICJ
Sequence: MHEYRTHDCGALRAADAGITARLSGWVNVKRDHGGLLFIDLRDHYGITQCVFPAGSPVFAAAEALRAESVITVTGRVVKRDADTVNPRLPTGEIELVAETVEVQSTADVLPIQVAGEAQFPEELRLRYRFLDLRREKLHRNIMLRANVIAWLRREMTARGFTEFTTPILTASSPEGARDFLVPSRVHPGQFYALPQAPQQFKQLLMVAGFDRYFQIAPCFRDEASRADRAPGEFYQLDFEMSFVTQEDVFATIEPVLGGLFREFGGGRGVTQWPFPRIAYDEALLKYGSDKPDLRNPLLITDVTEAFRDSGFGLFAKIVAGGGVVRAIPAPGTGGNPRSFFDKLNDWARSEGAGGLGYIIFAPDGAKGPIAKNLEPARAEAIREATGASVGDAVFFAAGKPLEAAKFAGTVRTKLGTDLGLIDGAKFEFCWIVDFPMYERDEETGQIVFSHNPFSMPQGGLEALNGQDPLTIKAFQYDIVCNGVELSSGAIRNHRPDIMLRAFEIAGYGAEEVEARFGGMLNAFRYGAPPHGGSAPGVDRMVMLLADEPNLREVIAFPLNQQGQDLLMGAPAPVPAARLKELSLAIALPPAPKKG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR8_NYMAL
Sequence: MGRDTIADIITYIRNADMDKKGTVRIPSTNITENIVKILLREGFIENVRKHRENNKDFLVLTLRHRRNRKRAYRNILKRISRPGLRIYSNSQRIPRISGGIGVVILSTSRGIMTDREARLERIGGEILFYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: WNT2_CHLAE
Sequence: MNAPLGGIWLWLPLLLTWLTPEVNSSWWYMRATGGSSRVMCDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKMGSAKDSKGIFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANERFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCGCKFHWCCAVRCQDCLEALDVHTCKAPKNADWTTPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: GLYOX_PSEPK
Sequence: MSKQVVVVGGGVIGLLTAFNLAAKVGQVVVCDQGEVGRESSWAGGGIVSPLYPWRYSPAVTALAHWSQDFYPQLGERLFASTGVDPEVHTTGLYWLDLDDEAEALAWAAREQRPLSAVDISAAYDAVPVLGPGFKHAIYMAGVANVRNPRLVKSLKAALLALPNVSLREHCQITGFVQEKGRVTGVQTADGVLAADEVVLSAGAWSGDLLRTLGLELPVEPVKGQMILFKCAEDFLPSMVLAKGRYAIPRRDGHILVGSTLEHAGYDKTPTADALESLKASAVELLPELEGATVVAHWAGLRPGSPEGIPYIGPVPGHEGLWLNCGHYRNGLVLAPASCQLFTDLLTGAEPIIDPAPYAPEGRLG
What is the function of this protein?
Catalyzes the oxidation of glycine, leading to glyoxyl imine and hydrogen peroxide as primary products; glyoxyl imine is used for the biosynthesis of the thiazole ring of thiamine.  Otherwise, glyoxyl imine is spontaneously hydrolyzed in water to produce glyoxylate and ammonia.  Can also use sarcosine (N-methylglycine) as substrate, and, to a lesser extent, N-ethylglycine and D-proline.  Has no activity towards other amino-acids D-Asp, D-Glu, D-Gln, D-His, D-Leu, D-Lys, D-ornithine, D-Trp, D-Val, L-Ala, L-Asp, L-Glu, L-His, L-Leu, L-Lys, L-Met and L-Pro.
What are the official names of this protein?
Glycine oxidase, GO.
What is the protein family that this protein belongs to?
Belongs to the DAO family. ThiO subfamily.
Protein: ADE_ACIAD
Sequence: MNQSELIRALPKAELHVHIEGTFEPELMFEIAQRNHIDIPYKSVEEIKKAYNFHNLQSFLDIYYAGANVLINEQDFYDLAWAYFKKCAEDRVVHTEMFFDPQTHTERGVSFEIVLNGLKRACKDAKEHLGISSHLIMCFLRHLSEEDAFKTLEQALPYKADIIAVGLDSSEVGHPPSKFARVFEKAREEGFLVVAHAGEEGPPEYVWEALDLLKVNRIDHGVRSEEDPALMQRLIQEKMPLTVCPLSNLKLCVVNDMKEHNIRRLLNQGVHVTVNSDDPSYFGGYMNDNFVAIQAALDLSNEELKKLAINSFEASFIDEEEKQNWIEEINQI
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: PEPA_ASPFU
Sequence: MVVFSKVTAVVVGLSTIVSAVPVVQPRKGFTINQVARPVTNKKTVNLPAVYANALTKYGGTVPDSVKAAASSGSAVTTPEQYDSEYLTPVKVGGTTLNLDFDTGSADLWVFSSELSASQSSGHAIYKPSANAQKLNGYTWKIQYGDGSSASGDVYKDTVTVGGVTAQSQAVEAASHISSQFVQDKDNDGLLGLAFSSINTVSPRPQTTFFDTVKSQLDSPLFAVTLKYHAPGTYDFGYIDNSKFQGELTYTDVDSSQGFWMFTADGYGVGNGAPNSNSISGIADTGTTLLLLDDSVVADYYRQVSGAKNSNQYGGYVFPCSTKLPSFTTVIGGYNAVVPGEYINYAPVTDGSSTCYGGIQSNSGLGFSIFGDIFLKSQYVVFDSQGPRLGFAPQA
What is the function of this protein?
Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates.  The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site.  Shows a broad primary substrate specificity.  Favors hydrophobic residues at the P1 and P1' positions, but also accepts a lysine residue in the P1 position, leading to the activation of trypsinogen and chymotrypsinogen A (By similarity).  Can catalyze hydrolysis of the major structural proteins of basement membrane, elastin, collagen, and laminin.  Thought to play a significant role in virulence (PubMed:7558282).
What are the official names of this protein?
Aspergillopepsin-1, Aspartic protease pepA, Aspergillopepsin F, Aspergillopepsin I, Aspergillopeptidase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PFAF2_GALME
Sequence: PDRRPPEDPITPPPPTKEEQRAGCGWRNENGVGFRIIGDKDGEAKFGEFPWMVAILKIEPVNDQDPEGQKLNVYVGGGSLIHPQVVLTAAHYVATAKTLRVRAGEWDTQTTKEIYPYQDRDVTHKEIHKDFNKGNLFYDIALLFLSQPMEMAPNVGVVCLPPRNERAEAGTRCFASGWGKDKFGKEGRYQVILKKVEVPVVDRNTCQDQLRKTRLGRHFMLHSSFMCAGGEPGRDTCRGDGGSPLVCPIQYEKGRYVQSGIVAWGIGCGEDRTPGVYVDVGNLRDWIDDKVAGRGIEPTVYTY
What is the function of this protein?
Binds and activates processed prophenoloxidases PPO1 and PPO2 and thus is involved in the activation of the prophenoloxidase cascade probably following the recognition of pathogen-derived products (By similarity).  Binds the A. niger cell wall component alpha-1,3-glucan, a fungal pathogen-associated molecular pattern (PAMP) that activates the host immune response (PubMed:34443685).
What are the official names of this protein?
Phenoloxidase-activating factor 2, PFAF2, Prophenoloxidase-activating factor II.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in the hemolymph.
Protein: FDRA_ECOLI
Sequence: MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ
What is the function of this protein?
Not known; multicopy suppressor of dominant negative ftsH mutations.
What are the official names of this protein?
Protein FdrA.
What is the protein family that this protein belongs to?
To E.coli YahF and some, to bacterial SucD.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NREB_STAA9
Sequence: MINEDSIQLDTLLKKYYEHSIEKIVFADDNGKIIAMNDAAKDILSEEDNYSAVANAICHRCEGYTNAYDVQSCKDCFLESMQVQATNFQVFMKTKDQKVMPFTATYQLIDQDRGIHAFTLQNVSSQIEQQEKLHQQRMMRKTISAQENERKRISRELHDSVIQEMLNVDVQLRLLKYQEDTTKLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLGLEAAFKSYFKQFEENYGIKIIYTSNIKNTRFDSDIETVVYRVVQEAILNALKYADVNEINVGIRQTGRHLVAEVIDAGNGFDPSSKPKGSGLGLYGMNERAELVSGSVNIETKIGEGTNVTLNIPI
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC.  NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT (By similarity).
What are the official names of this protein?
Oxygen sensor histidine kinase NreB, Nitrogen regulation protein B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_CALS4
Sequence: MEVEVKAKKAKEASRKMAVLDTETKNRALINMAEALLENADKILKANEKDVLEAERRNLKASLVDRLKLDEKRIKAMAEGLKEVASLKDPVGDIEEMWIRPNGLQIGKMRVPIGVIGMIYESRPNVTADAAGLCLKAGNAVILRGGSDAINSNIAIASILAEAAYKSGIPEGAIQLIENTDREEVNRMMKLNGLIDLIIPRGGTSLIKNVIENSTVPVIETGVGNCHIFVDESANFEMAKDIIVNAKVQRPGVCNAVETVLVHKGIAERFLPVMVKELSSHGVEIRGCELTKRICPDVKEATEEDWATEYLDLILAVKVVENIDEALEHISKYSTGHSESIVTENYTNAMRFLKSVDSAAVYVNASTRFTDGGEFGFGAEIGISTQKMHARGPMGLKELTTYKYVILGSGQIRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WTF16_SCHPO
Sequence: MKNNYTSLKSPIDEGDESKTGHEIDLEKGLLPEYDSEEEGALPPYSDHARVSNSPNTHRENNPSRSTDNSSPFLIKLLISFTPIYVLNVLAICYLKYKDAFFKNYGAAEWTLFGFWCLVCTLALIFLTYFYETWTKAVKVTAVGLYNSRKKWVVIIWLLWVVICFVLFGCIKFGNLNLDKALICSTCSISAALLLFLLYVRLPFWTLKHMFSGLFQVLGVQSCVVIVTKGLMYLFDKHIDATGYEIEATSLFVIGNFFFFYEMECPGALKRMPKFIRNGIASFLEGIGNAIGRIGNAFRGANDNNNNIPLEETEAESEV
What is the function of this protein?
Acts as a suppressor component of the dual wtf meiotic drive system, and can suppress but not confer meiotic drive by compatible poisons (By similarity).  Wtf meiotic drive systems promote unequal transmission of alleles from the parental zygote to progeny spores by encoding a poison and an antidote from the same locus; the poison is trans-acting and forms toxic aggregates in all spores within an ascus, wherease the antidote is spore-specific and targets aggregates for degradation by the vacuole (By similarity).  Meiotic drive by wtf systems therefore lead to poisoning of all progeny that do not inherit the dual poison/antidote allele, or express a compatible antidote (By similarity).
What are the official names of this protein?
Meiotic drive suppressor wtf16.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.