PharMolix/UniProtQA huggingface dataset:
Protein: CH10_ALKCK
Sequence: MLKPLGDRIIIEQIQSEEKTASGIVLPDSAKEKPQEGKVVAVGTGRVTDNGEKVALEVKEGDSIIFSKYAGTEVKYEGTEYLILRESDVLAIIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMGYA_ARATH
Sequence: MAFDLHHGSASDTHSSELPSFSLPPYPQMIMEAIESLNDKNGCNKTTIAKHIESTQQTLPPSHMTLLSYHLNQMKKTGQLIMVKNNYMKPDPDAPPKRGRGRPPKQKTQAESDAAAAAVVAATVVSTDPPRSRGRPPKPKDPSEPPQEKVITGSGRPRGRPPKRPRTDSETVAAPEPAAQATGERRGRGRPPKVKPTVVAPVGC
What is the function of this protein?
Binds A/T-rich DNA with a highly dynamic distribution into the nucleus.
What are the official names of this protein?
HMG-Y-related protein A, AtHMGA, High mobility group A protein.
What is the protein family that this protein belongs to?
Belongs to the HMGA family.
Protein: MRAY_HELPY
Sequence: MLYSLLYGYFNINLFQYLTFRAGLGFFIAFFLTLFLMPKFILWAKAKKANQPISSFVPSHQNKKDTPTMGGIVFVFATIVASVLCASLGNLYVLLGLIVLVGFSFVGFRDDYTKINQQSNAGMSAKMKFGMLFILSLIVSVLLSLKGLDTFLYAPFLKNPLFEMPTMLAVGFWVLVFLSTSNAVNLTDGLDGLASVPSIFTLLSLSIFVYVAGNAEFSKYLLYPKVIDVGELFVVSLALVGSLFGFLWYNCNPASVFMGDSGSLALGGFIAYNAIVSHNEILLVLMGSIFVIETLSVILQVGSYKTRKKRLFLMAPIHHHFEQKGWAENKVIVRFWIISMLSNLVALLSLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPD1L_MOUSE
Sequence: MAAAPLKVCIVGSGNWGSAVAKIIGSNVKTLQKFSSTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAVPNLSEAVQDADLLVFVIPHQFIHKICDEITGRVPEKALGITLIKGIDEGPDGLKLISDIIREKMGIDISVLMGANIASEVAAEKFCETTIGSKVMQNGLLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFAKIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILRQKGLLDKFPLFTAVYQICYEGRPVTQMLSCLQSHPEHI
What is the function of this protein?
Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L.
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37A_HALSA
Sequence: MANQSSTGSAGRFGARYGRVSRRRVSDIEGTMNEDHACPDCGSEAVSREGTGIWQCGKCGYKYAGGAYQPQTPSGKTVTRSIRTALGETGDSNSE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
Protein: MNTP_RHOP5
Sequence: MTPGAIAILSLSMSTDAFAAAVSRGASHRPGVVSAVKAGFVFGVIEAITPLIGWSLGLVAADLVKEVDHWIAFGLLTIVGGKMIWEATRSQDHHEEGAAPKRSNRWALIATAVGTSIDAAAVGVGLAFIGANIWVIAASIGFTTFVCTTVGMLIGKTVGQRFGKMAELIGGLALVGLGAMILIQHTGVLKTQLG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAA_STRPN
Sequence: MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFLPRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYSPKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLGKTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLIDDIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQTITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVKKIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVLARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKKKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANCY_PROMT
Sequence: MVRKIFQTNAELKDWLSGQNSAIIFIPTMGGLHPGHQYLIQKAKEKKTNTNQIILVSIFVNPLQFSKGEDFKKYPRNIKRDAELAFSAGADAIWAPEYDEVFPGGADSHFKIEVPKTLHNQLCGAERKGHFDGVATVIIRLIKIIKPKKLILGEKDWQQLIIIRKLFQELSIPVKIESYSTQRDQSGFAYSSRNSYLSDSERVNAQSLPNAIKEAKTEFDKGKVINLTKIASIFKENNLKIEYLKIVDPFSLKETENINRLCLLAIAVKCGSTRLIDHTFLMHRKPIIAIDGPAGAGKSTVTKAFAKKLGFIYLDTGAMYRAVTWLIISNSIDPNDQAEIKNILKDSKLEFKNSSFVEQKIFINNIDVTEKIRSPQVTSMVSEIAKQQFVREVLTRKQQVIGNNGGLVAEGRDIGTAVFPDADLKIFLTASPTERAKRRALDLHKRGYEFSSIEDLEKEIKERDKKDSERKIAPLKKAQDAIELVTDGMNIEDVLKELIDIFRSKIPEEVWPTPNS
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM8A_HUMAN
Sequence: MDSSSSSSAAGLGAVDPQLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPGPKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.  Probably necessary for normal neurologic development.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim8 A, Deafness dystonia protein 1, X-linked deafness dystonia protein.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: 3SX_MICSU
Sequence: LKCYGIFRKIMTCPQGQNICEKFAYSPMHNGWMYSWGCTSNCHKGPLDKCCSTDLCNY
What is the function of this protein?
Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site.  Binds to and inhibits the endogenous nicotinic acetylcholine receptors (nAChR) in the human rhabdomyosarcoma TE 671 cell line with an IC(50) of 266 mM.  Not toxic to mice by intraperitoneal injection or to zebrafish by injection at the back dorsolateral region.
What are the official names of this protein?
Short neurotoxin MS11, Three-finger toxin, 3FTx.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1032_STAEQ
Sequence: MNDSLIRIKQNFIEYILFNYRFKSRITVWVLNYLKANQDKLNNVHFVNSKINNHYTLEIAEVDATASAIQLSKDNKSYINTNQIFNYIANHTLRLDIQIHFANCHIRESRLDDLILMQLIHSPSYSSYVQDLYSISMDKRKQTFIIQTLQNNIDLSLQMNEPDYFYQLTQILNVLKSKDIQSTLHER
What are the official names of this protein?
UPF0302 protein SERP1032.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: SYR_ALIFM
Sequence: MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQKVLDVLDLDGIASKTEIAGPGFINIFLSEEFLAKQAEAALADKRLGVAKEEQQNIVADYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIGDWGTQFGMLIANLERIQKEKGEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQSGDEFCAEMWKKLVDVTMVQNQRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQKQGLAVESEGAQVVFLDEYKNKDGEPMGVIVQKRDGGFLYTTTDIACAKYRYEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVPESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEERAAKLIEEKNKDLPAEEKAKIATTVAMAAVKYSDLSKHRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFSKAGLSMDELTGEVKITDEKEKALVAKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPILNNEDDAVKQSRLKLAALTAKTIKQGLELLGIETLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYNS_TALMQ
Sequence: MSHLNIATLDASQHPYLPASSQTLFAAKAKKKLSFEEISQEIGRNEVATAAIFYGQAKASPEDITNLSKALDIPYELLEEQLSGFPDRGRSVEMPPREPLIYRLFEIVQNYGYAYKAVLNEKFGDGIMSAISFSTKVEKETDADGNNWAVITLRGKWLPFSRY
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: LDH_BACSU
Sequence: MNKHVNKVALIGAGFVGSSYAFALINQGITDELVVIDVNKEKAMGDVMDLNHGKAFAPQPVKTSYGTYEDCKDADIVCICAGANQKPGETRLELVEKNLKIFKGIVSEVMASGFDGIFLVATNPVDILTYATWKFSGLPKERVIGSGTTLDSARFRFMLSEYFGAAPQNVHAHIIGEHGDTELPVWSHANVGGVPVSELVEKNDAYKQEELDQIVDDVKNAAYHIIEKKGATYYGVAMSLARITKAILHNENSILTVSTYLDGQYGADDVYIGVPAVVNRGGIAGITELNLNEKEKEQFLHSAGVLKNILKPHFAEQKVN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_NEIG1
Sequence: MINDIQKTAEGKMQRSVEVLKENLAKVRTGRAHTGLLDQVEVEYWGSMVPVSQVANVTLLDARTIGVKPFEGNMAAKVEKAIRDSNLGLNPAAVGDLIRVPMPMLTEERRKDLIKVVRGEAEEGRVSIRNVRRDANDHIKKLLKDKEISEDEARRGEEAVQKLTDKYIAEADKVLAAKEEDLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS24_AERPE
Sequence: MSVPQAREARRIDLGEMGWGEVQVDFYNPLVKRREIVMILHHELKPTPMRIMLRQKLAEVLGVDIKRIYIRYIKTGYGAGLSKVRVHVYDSPERALSFEPKYIIERNGGVNPFEEAEG
What are the official names of this protein?
30S ribosomal protein S24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: FMT_SYNAS
Sequence: MAKISILFMGTPEFALPSLEILVRNGYPIAAVVTQPDRPKGRGKQLVAPPVKIAATSYQIPVLQPPGIKDPAFLEILEKISPDLIVVAAFGQILPKTVLDFPPLGCINVHPSLLPRYRGAAPINWTLIHGETRTGVTIMYMDEGLDTGDILLQEETPIPPEENFGILHDRLSNLGADLLLRAVRLLEAHQAPRNPQEDSLSSYAPMLKKEDGLIRWSEEVSTIANRIRGLSPAPGAYTFLNGKTLKIFAAAGIEQSVPGQPGEVGKLTDQGLQVTAGNGYVVLQDVQMENRKRMNVSDFLRGHKLSTGTVLG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: YHHS_ECOL6
Sequence: MPEPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVISLQYFATLLSRPHAGRYADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVAIALLLTWRLKKRPPVEIPEAASSS
What are the official names of this protein?
Uncharacterized MFS-type transporter YhhS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YhhS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WNK4_ARATH
Sequence: MNMNQVAEYVETDPTGRYGRFAEILGRGAMKTVYKAIDEKLGIEVAWSQVKLKEVLRSSVDLQRLYSEVHLLSTLNHKSIIRFYTSWIDVHNHTLNFITELFTSGTLRQYKNKYLRIDIRAIKSWARQILEGLVYLHEHDPPVIHRDLKCDNIFVNGHLGQVKIGDLGLARMLRDCHSAHSIIGTPEFMAPELYEENYNELIDVYSFGMCFLEMITSEFPYSECNHPAQIYKKVVGGKLPGAFYRVGDIEAQRFIGKCLVSASKRVSAKELLQDPFLASDESWMVYTSGAGNPKPFLNENEMDTLKLEDDELRTEMSIAGKLGAEDNKIDLEVQIAYDNGLANNVFFPFDIMNDTSIDVAKEMVKELEIIDWEPVEIAKMIDGAISSLVSDWKYEEDDETPHDHHRHRTDSFHSSSSHASSSQASLSNYMARGLQDWVQDDLHDETYSQSSSHSGSYSNLNYIAVDEYSSQSPVMSRTHNMTRFCPEESSHLQSGQANAYAASSSTNRSLASDNRTLTRNRSLVDVQRQLLHRSPGEEARKRRLFKTVGDVETVGFQSPYAVSRKPPSSRR
What is the function of this protein?
May regulate flowering time by modulating the photoperiod pathway.
What are the official names of this protein?
Probable serine/threonine-protein kinase WNK4, AtWNK4, Protein kinase with no lysine 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily.
Protein: KLH26_MOUSE
Sequence: MAESGGSSGSSQSPERPSSLADRNGALKCTFSAAGHSTGLLQGLAALRAQGQLLDVVLTVNSEAFHAHKVVLAACSDYFRAMFTGGMREANQAVIQLQGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEDFLKAAMSVETCLHIGQMATTFSLTSLRESVDAFTFRHFLQIAAEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRARASLVLRHVRFPLMQPAELVDSVQTLDVMLDDALCRQYLLEAFSYHVLPCRQHDMQSPRTAVRSDVASLVAFGGTPYTDSDRAVSSKVFQLPEPGARHFRELTEMELGCSHAGVAVLDNFVYVAGGQHLQHRSGEGAVDACYRYDPQRNRWLRLRALRESRVQFQLTALGGLLYATGGRNRAGSLASVERYCPRRDSWDFACPLKRRTWGHAGAAAAGRLYISGGYGVSAEDKKALQCYDPAADRWEPRAPMREPRVLHAMLGAAGRIYALGGRMDHVDRCFDVLAVEYYVPDADQWTSVTPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTETDEWERDLHFPESFAGIACAAVLLPRSGHGR
What are the official names of this protein?
Kelch-like protein 26.
Protein: NORR_VIBVU
Sequence: MTSLIAQWLHITQDLNSALTRQARFDTLLTTIRDVLNCDSSALLLFEDQHFKPLAINGLAKEVLGRRFSIEQHPRLEAIARAGDIVRFPSESTLPDPYDGLITNHQGKLHVHSCIGLPLLIDDQLIGAITIDALDPNQFDQLKNQELRFISALAAGGLHTALLLEQLETQASLPRESYAEKRTLSNEIIGNSQGMRTLQDQIDAVANTELSVLVMGETGVGKELVANAIHHRSDRASNNLVYLNCAALPESVAESELFGHIKGAFTGAISHRKGKFEQADGGTLFLDEVGELSLELQAKLLRALQYGDIQRVGDDRHIRVNTRIVAATNRVLHEEVKAGRFRADLYHRLSVFPLHVPPLREREEDVILLAGFFAEQVRGKLGLHSVRLSPSLVAELREYHWPGNVRELEHVIKRAAVLAKARTPQMDIELISQDFDIKTPTSPMMPTVAASQAQHEIHSDIGLKQATDAFQKKLILRALESNQGNWAATARQLELDSGNLHRLAKRLGIK
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: CDC63_SACS2
Sequence: MHVIRETLKGGKGEVIKNPKVFIDPLSVFKEIPFREDILRDAAIAIRYFVKNEVKFSNLFLGLTGTGKTFVSKYIFNEIEEVKKEDEEYKDVKQAYVNCREVGGTPQAVLSSLAGKLTGFSVPKHGINLGEYIDKIKNGTRNIRAIIYLDEVDTLVKRRGGDIVLYQLLRSDANISVIMISNDINVRDYMEPRVLSSLGPSVIFKPYDAEQLKFILSKYAEYGLIKGTYDDEILSYIAAISAKEHGDARKAVNLLFRAAQLASGGGIIRKEHVDKAIVDYEQERLIEAVKALPFHYKLALRSLIESEDVMSAHKMYTDLCNKFKQKPLSYRRFSDIISELDMFGIVKIRIINRGRAGGVKKYALVEDKEKVLRALNETFEDSISIGDFDDVGEN
What is the function of this protein?
Involved in regulation of DNA replication.  May play essential roles in origin recognition and cell cycle control of replication.  Binds to DNA, with a preference for molecules that contain a bubble, a fork, or a tail.  Inhibits the binding of the MCM helicase to the origin DNA and inhibits its DNA helicase activity.  Also regulates the DNA polymerase and the nuclease activities of PolB1.  Inhibits the DNA-binding activity of Cdc6-1 and Cdc6-2.
What are the official names of this protein?
ORC1-type DNA replication protein 3.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: Y1918_LACLS
Sequence: MFTQNHFEIFSIDGLEARMAEIRSEIQPVFSEIGQKLLTKLSAKISNQEFYFHIAQHRRRTANAPENTWSAISTKARGYKMEAHFQLGIWEDYVFIYLSMIDQPKKQKEYAELLTNLSVEKMLTEDFIISKDHTKAEVFPLSAFSEAAERLGKVKKSELEIGRLWSKERFDGKEDSKILAEMLETIDQLLPIYQKLMEV
What are the official names of this protein?
UPF0637 protein LACR_1918.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: IDI_ENT38
Sequence: MSIQEHVILVNDQGEVVGTQEKYAAHTSHTSLHLAFSSWLFNDRGQCLVTRRALSKIAWPGVWTNSVCGHPQIGETTEQAIARRCRFEVGVEIAQLTPIAADFRYCEIDPSGIVENEICPVFAAQIVSPLKVNPDEVMDYQWVELTSLLRALEATPWAFSPWMVSEAANASEKLKHFADNVKA
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STKLO_ARATH
Sequence: MVTPKQIDFSSCVGADNSNGTLSHRRSPRNIPSSKRAASVAEEETMKKKMKMKKKKKKLDPPLIVRIWNEEDELSILKGLVDYRAKTGFNPKIDWDAFCSFLGSSIVERFSKDQVLSKIRKLKRRFHVHSEKINQGNDPKFTRSSDSEAFGFSSMIWGQGDDDGMDKEHEVNGNGAAENRTNESGEEMLKEHEEEVANTELLNENGAAKTTENGTSSGKERHDEDNDDDDELCAVQDAFEAVMSQGLSGYQKKLQLEKLMNLGNGKRRELSDEWKALCVEETRFNIKKLRFSAKLAEAANDS
What is the function of this protein?
DNA-binding protein, which specifically recognizes the GL1 enhancer sequence (PubMed:12535344).  May be involved in leaf initiation (PubMed:12535344).  May play redundant roles with GPL1 and GPL2 in cytokinin responses by regulating the transcript levels of type-A ARR response genes (PubMed:18162594).  Involved in stress responses (PubMed:21875893).  Plays a repressive role in cell expansion by counteracting the positive role of CPR5 in this process, but does not regulate cell proliferation or endoreduplication (PubMed:21875893).  May play a role in plant defense (PubMed:29192025).
What are the official names of this protein?
GLABROUS1 enhancer-binding protein, Probable transcription factor At4g00270, Protein GeBP, Protein STOREKEEPER RELATED 1, Storekeeper-like protein At4g00270.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus.
Protein: RL37_METB6
Sequence: MSKGTPSMGKMNKMTHIACRRCGRISFHAQKKVCSSCGFGRSTKMQSFKWDTKRPKTPTH
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: SYT_SYNSC
Sequence: MAGPEPEPVSSAAATTPAPSAPVVLPKTSESDQLLKIRHSMSHVMAMAVQQLFPKARVTIGPWTETGFYYDFDNPDPFTEADLKAIKKGMIKIINKKLPLQRVEVSRNEAEEKIKAQNEPYKLEILQGLHEPITLYTLGEDWWDLCAGPHVDHTGQLNAKAFELESLAGAYWRGDETKAQLQRIYGTAWESPEQLAEHKRRKEEALRRDHRRIGKDLDLFSIEDEAGAGLVFWHPRGARIRLLIEEFWRQAHFEGGYELLYTPHVADISLWKTSGHLDFYAESMFGPMEVDEREYQLKPMNCPFHVLTYASKLRSYRELPIRWAELGTVYRYERPGVMHGLMRVRGFTQDDAHVFCLPEQISDEILKILDLTERILSAFDFSNYEINLSTRPEKSIGEDAVWDLATKGLIEALERKGWAYKIDEGGGAFYGPKIDLKIEDAIGRMWQCSTIQLDFNLPERFELDYIAADGSKQRPIMIHRAIFGSLERFFGIMTENYAGDYPFWLAPEQVRLLPVTDEVQPYAEQLLDQLTKAGVRATVDRSGDRLGKLIRTGEQMKIPVLAVIGAKEAEQNAVSLRSRRDGDLGVTAVSDLLSAAQMANSERAAGLELNR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCA_VIBC1
Sequence: MIKRERIVKSVLAHVPKDAINQFVSRGSTPTSFSVLFMAAIVGTLAGLVGTYFEIAVHFVSETRTEWLKSEIGSVLPLWLAAILISGALAFIGYYLVNRFAPEASGSGIPEIEGAMDNIRSVRWWRVIPVKFFGGMGALGSGMVLGREGPTVQMGGAVGRMVTDIFRVKDDDTRHSLLASGAAGGLAAAFNAPLAAIMFVVEEMRPQFRYSLISIRAVIISAIMANIVFRAINGQEAVITMPQYQSPELQSLWLFLLLGSLFGVFGVVFNKLITIAQDSFVALHKNDRKRYLITGTILGGVFGLLLLYVPQLTGGGIGLIPDITNGNYSISILVMLFVGRVITTLLCFGSGAPGGIFAPMLALGTLFGYAFGASADMLLPSLTIEPGVFAIAGMGALFAATVRAPITGILLVIEMTNNYYLILPLIITSLGAVIVAQLLGGQPIYSQLLHRTLKNDKLRQQDLPENQA
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 3MGH_BURO0
Sequence: MRRSKTAAPWPGTIVPRAFFNRMATEVAPQLLNKILAAADGRAGRIVEVEAYAGALDPAAHTYRGKTPRNATMFGAPGHFYVYFTYGMHWCCNCVCGPDGAGTGVLIRALEPLHGLEQMRAARPPRTRDRDLCRGPARLTQAMGIGGAQDGVDLVGAREGFAIVDDGMAPPADLAGGPRIGIRVGQDLPWRWSVPGNRYVSGAAPRI
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: RECA_SHESH
Sequence: MKIDANKEKALNAVLGQIEKQFGKGSIMKLGENRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLEVIAAAQREGKVCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQTNTMLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKDRDEVIGNETRVKVVKNKIAAPFKQAEFQILYGQGINSTGELVDLGVAHKLVEKAGAWYSYKGDKIGQGRANAGKYLIENPAVAQEIDVALRALLLTPAAPVADSATGDENIDLETGEVF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.