PharMolix/UniProtQA huggingface dataset:
Protein: DNAB_PASMU
Sequence: MAKKNAQIPSKPLEQGIVPPHSLEAEQSVLGGILIHPAHWDSISDMLIADDFYLAAHRVIFQEMENLLRQGKPIDLINLYEFLREKNLSEDVGGFAYLAELSKNTPSVSNIVSYAAIVRDRAILRDLISVSNDVAQSCYTTKGMEVKDILDEAERKVFAISEKRTTSNEGPQNICAILEKTIDRIELLSKTEGHNGITGVSTGFDALDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAALKSDKPVLVFSLEMPAEQIMMRSLASLSRVDQTKIRTGQGLDQSDWSKIGSTMGLFANKPNLYIDDSSGLTPTELRSRARRVYRENGGLSLIMVDYLQLMRAPGFADNRTLEIAEISRSLKALAKELEVPVIALSQLNRTLENRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYNENSEDKGVAEIIIGKQRNGPIGRVRLAFRGQFSRFDNLAEQRDIRDDY
What is the function of this protein?
Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.
What are the official names of this protein?
Replicative DNA helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DnaB subfamily.
Protein: KGD_MYCBP
Sequence: MANISSPFGQNEWLVEAMYRKFRDDPSSVDPSWHEFLVDYSPEPTSQPAAEPTRVTSPLVAERAAAAAPQAPPKPADTAAAGNGVVAALAAKTAVPPPAEGDEVAVLRGAAAAVVKNMSASLEVPTATSVRAVPAKLLIDNRIVINNQLKRTRGGKISFTHLLGYALVQAVKKFPNMNRHYTEVDGKPTAVTPAHTNLGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTTEDFAGVTISLTNPGTIGTVHSVPRLMPGQGAIIGVGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHELLLSDGFWDEVFRELSIPYLPVRWSTDNPDSIVDKNARVMNLIAAYRNRGHLMADTDPLRLDKARFRSHPDLEVLTHGLTLWDLDRVFKVDGFAGAQYKKLRDVLGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVETKHVKPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVARLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYMYDVVDTKRGARKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVQPSESVESDQMIPAGLATAVDKSLLARIGDAFLALPNGFTAHPRVQPVLEKRREMAYEGKIDWAFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRHSVLIDRHTGEEFTPLQLLATNSDGSPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHKAAVSEIKDFTEIKFRSVLEEPTYEDGIGDRNKVSRILLTSGKLYYELAARKAKDNRNDLAIVRLEQLAPLPRRRLRETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSSKVHAVEQQEILDEAFG
What is the function of this protein?
Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation.  Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA).  Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha-ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy-3-oxoadipate (HOA), which spontaneously decarboxylates to form 5-hydroxylevulinate (HLA).  And is also a component of the 2-oxoglutarate dehydrogenase (ODH) complex, that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2).  The KG decarboxylase and KG dehydrogenase reactions provide two alternative, tightly regulated, pathways connecting the oxidative and reductive branches of the TCA cycle (By similarity).
What are the official names of this protein?
Multifunctional 2-oxoglutarate metabolism enzyme, 2-hydroxy-3-oxoadipate synthase, HOA synthase, HOAS, 2-oxoglutarate carboxy-lyase, 2-oxoglutarate decarboxylase, Alpha-ketoglutarate decarboxylase, KG decarboxylase, KGD, Alpha-ketoglutarate-glyoxylate carboligase.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family. Kgd subfamily.
Protein: TOP3_CANAR
Sequence: MLISTLPLLLHEQLAQSTRMRVLCVAEKNSIAKEVAKILSGGRARPRNSLYKYVKNYDFQYTFQGLGPCDVTMTAVAGHVLTTDFGPEYAWGKCPPGRLFDAPFLTKPPPDRDQRAGILKNIIREARNADRLMIWTDCDREGEYIGWEIMSVAQGANPRLNLQTTWRAQFSHLEPQHIVAAANNPKALDMKLVAAVECRTEFDLRVGTLFTRFLTNIYKSKRLVGEKEVVSYGTCQFPTLSFVVDRYVRVRNFRPEPFWSIDLAVTKNGQKVNFSWSRNHLFDRMFVYVIYAQLLEGPQKPRIVGVSTKPTSHYKPLPLTTVDLQKCCSRYFKMLAKAALDAAELLYTAGYISYPRTETDQFPAKLDLKGYITKQTLSLDWGTHATRLLQGSFRPPRGGKHDDKAHPPIYPVKSASLDTLRPDQRKVYEFVVRRFLACCSDDARGLQTKVDLQWRSERFTALGLQVTERNFLDVYPYSDWKSLAQLPEFAEGEEVTPSSCKVKEGKTSPPNYMTEAELIALMDANGIGTDATIADHVEKIAQRNYVTRRKIGKSEVFIPTSLGISLIDAFDAILIDRISLLKPFLRRAMEGFLQKISRGEITKQDVISQLLPLYKEAFMESNQKGHVISDTFIQTSRGLS
What is the function of this protein?
Introduces a single-strand break via transesterification at a target site in duplex DNA.  Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.
What are the official names of this protein?
DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: DPOLA_ORYSJ
Sequence: MDEGSADAGASGRRSRARGSEAVARSAALERLRAIRDGGARAAAAVQVRIEAPIYDTVAEEDYAALVARRRKDAGAFIVDDDGLGYADDGREEDWTHRTIHSSSDEGSDGEDGAPRKRKQPRPQSKRPPQQSAAAASLSAAAAMMGKQRLSSMFTSSVFRKPGSDRGRDSSLAADSIVDDVIAEFAPDDNDREERRRRVGRVCAPAPAPTTTAHIKAENVAVDTAMAFRSDNVFEAHEVSDHGNDMDMELKPDVEMEPKLDTPLGASAELANNSNSLEEPKQEANGEVKIEKVHRLNAKIKTEDSRNGDMASATAGWMKICGDGDNAGGEGAVAANSNTGVDESSEFELKDGALPFYILDAYEEPFGANSGTVYLFGKVEVGKRFHSCCVVVKNMQRCIYAIPSSSIFPRDTISRLEKNSTTSDSSPSLRASLHELASGLKSEIADKLSDFNVSNFAMTPVKRNYAFERTDLPNGEQYVLKINYPYKDPALPTDLRGQHFHALLGTNNSALELLLIKRKIKGPSWLSISKFLACPATQRVSWCKFEVTVDSPKDISVLMTSTTLEVPPVVVAAVNLKTIINEKHNVHEIVSASVICCHRVKIDSPMRSEDWQKRGMLSHFTVMRKLEGSIFPIGLSKESSDRNQKAGSNVLALESSERALLNRLMIELSKLDCDVLVGHNISGFDLDVLLHRAQTCKVPSNMWSKIGRLRRSVMPRLTKGNTLYGSGASPGIMSCIAGRLLCDTYLCSRDLLKEVSYSLTQLAETQLKKERKEVSPHDIPPMFQSSGALLKLVEYGETDACLALELMFHLSVLPLTRQLTNISGNLWGKTLQGSRAQRVEYLLLHAFHARKFIVPDKFARSKEFNSTKRKMNPDTEAARPDEADPSIDDEGHHVDQGKTKKGPSYAGGLVLEPKKGLYDKYVLLLDFNSLYPSIIQEYNICFTTVDRSADGNVPNLPASKTTGVLPELLKSLVERRRMVKSWLKTASGLKRQQFDIQQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQNTVDLVQNNLNLEVIYGDTDSIMIHTGLDDISRAKGIAGKVIQEVNKKYRCLEIDLDGIYKRMLLLKKKKYAAIKVALDGSLRENIERKGLDMVRRDWSLLSKEIGDFCLNQILSGGSCDDVIESIHSSLVQVQEQMRGGQTELEKYIITKSLTKAPEDYPDAKNQPHVQVALRLKQNGYSGCSAGDTVPYIICSQQDSESTHSGGIAQRARHPEELKRNPDKWMIDIDYYLSQQIHPVVSRLCASIQGTSPARLAECLGLDSSKFQSRLTESDNQDTSSMLLSVIDDEDERYRGCEPLRLSCPSCSTTFDCPPVSSLIIGSSSGNVSNPNEGNDASINFWRRMRCPRCPDDTDESRVSPAVLANQMKRQADSFINLYYKGLLMCDDEGCKYSTHSVNLRVMGDSERGTICPNYPRCNGHLVRQYTEADLYRQLSYFCYVVDATRCLEKLDQKARLPFEKEFAALSQTINLALMEVQKIRDRCAFGWVQLKDLAISI
What is the function of this protein?
Polymerase alpha in a complex with DNA primase is a replicative polymerase.
What are the official names of this protein?
DNA polymerase alpha catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VEGFB_RAT
Sequence: MSPLLRRLLLVALLQLACTQAPVSQFDGPSHQKKVVSWIDVYARATCQPREVVVPLSMELMGNVVKQLVPSCVTVQRCGGCCPDDGLECVPIGQHQVRMQILMIQYPSSQLGEMSLEEHSQCECRPKRKESAVKPDRVAIPHHRPQPRSVLSWDSAPGASSPADIIHPTPAPGPSAHAAPSAVSALIPGPAVAAADAAASSIAKGGA
What is the function of this protein?
Growth factor for endothelial cells.  VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis (By similarity).
What are the official names of this protein?
Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Protein: PP4R1_RAT
Sequence: MADLSLLQEDLPEDADGLGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENVFNRQMVARSLLDTLREVCGEERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKYLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERLDVETKVCPVLIDLTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQCFKDESKSSEDKDRIRDDGVVQEEQSRPEDAPSDLSAPHSSARLDGTLEGCAAETPGDSAGDMRVPADSSLLCTLSSESPQEAASDAESGKKHDNNSKSASRPDVGTSSPEPTPLDQEMFNSFHFWRTPLPQIDLDKELQQDPGERPSPERTGDAPAAPVPGSPSITMATRKELEEMIENLEPHMDDPDVKAQVEVLSAALRASTLDAHDEAGGAEQRSELQDDAVGAGGELPNCSISEDTSEPLVIAAEENMEATPDYIHGGADVGPGGGGGFSPDEERRPKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHMATPPTFGVELINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKEYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPSSTKLSEDAMSTASSTY
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4.  May play a role in regulation of cell division in renal glomeruli.  The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3 (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 1.
Protein: DUT_BRASB
Sequence: MTETIAIDVQILPHGEGLPLPAYQTAHAAGMDLLAAVAADAPLVLGPGSHAMVPTGLSLALPDGYEAQVRPRSGLAARHGVTVLNAPGTVDADYRGEICVLLINHGKEPFTIRRGERIAQMVIAAVARAALSITTTLSATARGSGGFGSTGR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: Y7281_DICDI
Sequence: MSNESKICLVNEDSIYYRGYDIKDLTAVSSFEEVSFLLIYGELPTERELIEYRSELQHYRYIPESLKQVLERIPIYAHPIDVLKTACSFYSTISPESKQNDIYRISNRLIGSFPSILFYWYHFSSNGIRINTLTEVNDSFARHFLKLLNRGNNNNINNNNKFTTEQDEEPILEYVKALDVSLILYAEHGIETASTFSCRLSASTGSDVYSCIGSSIGTMKGVLDDGGSSEAVMYLLQPMKSPEDADKKIMKMINNNQRIIGFSNEFDQRTPIIKEWSKQLSIINKNNNNNNNNNNNNNNNNNNNNNNNNSEDDDDDNSLQTISERVEEIMFDVLKVHANVDFYNATVFHQSNIPTLLFSAISVIARTTGWMANIIEQRCQSKNSLPSLIYTGSDPIPFTPINERVYYHNFKIPNSNL
What are the official names of this protein?
Citrate synthase-related protein DDB_G0287281.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: HEM1_SYNP6
Sequence: MHLAVVGLSHRTAPVAVREKLSIPEQQVEAAIQQLKSYPHIEEVAILSTCNRLEIYCVTRATEPGVREITQFLSEHSHLPLGELRPHLFVLLHQDAVMHLMRVAAGLDSLVLGEGQILSQVKTMYKLGQQYEGVGRILNRLLKQAVTAGKRVRTETSIGTGAVSISSAAVELAQLKVIARDDRSDGNLAGQRVLILGAGKMSRLLVQHLIAKGADTIQILNRTLGRAEELAKQYGGDLQIQVGLLSGLMNAIVEADIVFTSTSATDPILDRAKLEMVLAPEQRLMLIDIAVPRNVAADVVELTSVESYNVDDLREVVAQNQESRRKLAEEAEALLEEEVDAFDNWWQSLDTVPTINCLRDKIEMIREQELEKALSRLGTEFGDKHQAVVEALTRGIVNKILHDPMVQLRSQQDIEARRRAVDALQMLFNLDPQGQLSS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: MES10_ARATH
Sequence: MTYQKQYQMQTHHMQQQQLHHFVFVHGSCHGAWCWFKLAAKLKLDGHRVTAIDLGGSGVDTRQLHEVRLVSAYLEPLMSFMESLPENEKVVLVGHSYGGIGTSLAMERFPTKVSVGIFLSAYMPHHDSPPAVLIQEYFTRLPEGFAMDCEFTFEEGLEHPPSSVLFGTSFLKEKAYSNCQLEDLELAMALMKPSWLYTKEMGGEDLITKERYGSGKRVFIVCEGDNVVPEEIQKWMISNYEPHEVKRIEEAGHMAMLTKPHELSQLLQEIAAKYN
What is the function of this protein?
Methylesterase shown to have methyl jasmonate (MeJA) esterase activity in vitro.
What are the official names of this protein?
Methylesterase 10, AtMES10.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Methylesterase family.
Protein: ACPH_SALTY
Sequence: MNFLAHLHLAHLADSSLSGNLLADFVRGNPATHYPPDVVEGIYMHRRIDVMTDNLPEVREAREWFRHETRRVAPITLDVMWDHFLSRHWTQISPDFPLQAFVGYAHAQVATILPDSPPRFVNLNDYLWSEKWLERYRDMDFIQNVLNGMANRRPRLDALRDSWYDLDAHYDALEERFWHFYPRMMAQAARKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: RECA_ZYMMO
Sequence: MAPQNKVTTSGKDNNMDKQKALEAALAQIDRAFGKGSVMRLGSREKIEIDTISSGSLGLDIALGIGGLPRGRIVEIYGPESSGKTTLALHAIAEAQKAGGTAAFVDAEHALDPVYAKKLGVNTDDLIVSQPDTGEQALEITDTLIRSNAVDILVVDSVAALTPRAEIEGEMGDSHVGLQARLMSQALRKITGSINRSQTLVIFINQVRMKIGVMYGNPETTTGGNALKFYASVRLDIRRVGQIKDRDEIVGNATRVKVVKNKLAPPFKQVEFDIMYGEGVSKMGEILDLGVKAGIIDKSGSWFSHDSVRIGQGRENAKTFLREHPEMTEKIEKMIRHNTAEIADEMLDPSIPED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_LEPBP
Sequence: MKIGIIGAGSFGTALGSILADKGYDVTLWTRSEEQARSINENHMNSKHMPDLVLPDRLKASTDLIQVVKDKDMIVSAPPSHALSGILKEIKDHIPPKVPIVSASKGIENESLRLVSEIFESELPGQFHSQLSYLSGPSFAKEMVKRVPTIVSIASKNEATAKRVQEIFSFTYFRTYWTPDVVGVEVGGALKNVIAIAAGVADGLGFGQNTRAALITRGLNEITRMGIKMGADPMTFLGPSGMGDLVLTCCGEASRNRTVGFRLGKGESLKEILSSMNEVAEGVKTTLSTKNLADKLGVEMAITQEVYHMLYEDKDPKEVVRALMSRDLKREGV
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRB_CHLMU
Sequence: MLEKFVDSLWKFCRKSKFQYMTPVADAVDSFCFEPLHTPSSPPFVRDAVDVKRWMMLVVIALMPTVFVAIWNSGLQALVYQSSDPQIMEAFLHISGFTSYFSFVSKEIGIASVLFAGCKIFLPLLFISYAVGGTCEVLFAIIRKHKIAEGLLVTGMLYPLILPPTIPYWMAALGIAFGVVIGKELFGGTGMNILNPALTGRAFLFFTFPAKMSGDVWVGSNPSKIKESLAMMNSLAERSNFDGFSQSTCLQILNSTPPSVKRVHIDAIASNILKLEHVPSQEVLQSQFSTWAESFPGLTVDQLSLDQLQNFVTSPTAEGGLGLLPAHFDAAYSLTDAIYGIGKFSTGNLFFGNIVGSLGETSTVACLLGAGLLLLTGIASWRTMLSFGLSSLFFAWLFKIISILAAGQSGAWAPAKFFIPVYRHLFIGGLAFGLVFMATDPVTSPATKLAKWFYGAFIGFLTILIRLINPAYPEGVMLAILLGNVFAPSFDRIALKQYRQRRV
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-NQR subunit B, Na(+)-translocating NQR subunit B, NQR complex subunit B, NQR-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: T2R16_HUMAN
Sequence: MIPIQLTVFFMIIYVLESLTIIVQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNNFCSYFNLNYVLCNLTITWEFFNILTFWLNSLLTVFYCIKVSSFTHHIFLWLRWRILRLFPWILLGSLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLENFHQYQFQAHTVALVIPFILFLASTIFLMASLTKQIQHHSTGHCNPSMKARFTALRSLAVLFIVFTSYFLTILITIIGTLFDKRCWLWVWEAFVYAFILMHSTSLMLSSPTLKRILKGKC
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
What are the official names of this protein?
Taste receptor type 2 member 16, T2R16.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: T170A_DANRE
Sequence: MIEALIVGEMQDVQIGFVKQILSLNLVPRSNNTTCGNNTSLCDFSEMWYGVFLWAVVSSLIFHLPAALLALATLRRHKVARFFPLGILLMGIIGPLFGGVLTSAAIAGVYKAAGKSMFSLEALVFGVGQSLFIFIISFLRILATL
What is the function of this protein?
May regulate membrane morphogenesis in the endoplasmic reticulum (ER) by promoting ER sheet formation at the expense of ER tubules.
What are the official names of this protein?
Transmembrane protein 170A.
What is the protein family that this protein belongs to?
Belongs to the TMEM170 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope.
Protein: GATB_CHLT2
Sequence: MGIAHTEWESVIGLEVHVELNTESKLFSPARNHFGDEPNTNISPVCTGMPGSLPVLNKDAVRKAVLFGCAVEGDVALFSRFDRKSYFYPDSPRNFQITQYEHPIVRGGCIRAVVEGEEKTFELAQTHLEDDAGMLKHFGDFAGVDYNRAGVPLIEIVSKPCMFSAEDAVAYANALVSILGYIGISDCNMEEGSIRFDVNISVRPRGSRELRNKVEIKNMNSFTFMAQALEAEKRRQIEEYLSHPNEDPKKVVPAATYRWDPEKKKTVLMRLKERAEDYMYFVEPDLPVLQITETYIDEVRQTLPELPHSKYMRYITDFDIAEDLAMILVGDRHTAHFFETATMSCKNYRALSNWITVEFAGRCKAKGKTLPFTGILPEWVAQLVNFIDRGVITGKIAKEIADRMVSSFGESPEDILRRHPSLLPMTDDHALRAIVKEVVAQNTASVADYKNGKAKALGFLVGQIMKRTEGKAPPKRVNELLLAAMRDM
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: MZT1_MOUSE
Sequence: MASGSGPGAAASANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEALSSVIKELRKGTEALKAAENTS
What is the function of this protein?
Required for gamma-tubulin complex recruitment to the centrosome.
What are the official names of this protein?
Mitotic-spindle organizing protein 1, Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1.
What is the protein family that this protein belongs to?
Belongs to the MOZART1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle.
Protein: ERPA_BURCH
Sequence: MNAVTETAATTTDMPLPFVFTDAAADKVKQLIDEEGNPDLKLRVFVQGGGCSGFQYGFTFDEEVNEDDTVMNKNGVQLLIDSMSYQYLVGAEIDYKDDLNGAQFVIKNPNATTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: AKR2B_ARATH
Sequence: MASSSEKTPLIPSDEKNDTKEESKSTTKPESGSGAPPSPSPTDPGLDFNAFDFSGMAGILNDPSIKELAEQIAKDPSFNQLAEQLQRSVPTGSHEGGLPNFDPQQYMQTMQQVMENPEFRTMAERLGNALVQDPQMSPFLEALGNPAASEQFAERMAQMKEDPELKPILAEIDAGGPSAMMKYWNDKDVLAKLGEAMGIAVGADQTVAAEPEEAEEGEEEESIVHQTASLGDVEGLKAALASGGNKDEEDSEGRTALHFACGYGEVRCAQVLLDAGANANAIDKNKNTPLHYAAGYGRKECVSLLLENGAAVTQQNMDNKNPIDVARLNNQLDVVKLLEKDAFL
What is the function of this protein?
Exhibits chaperone activity toward chloroplast outer envelope membrane, mitochondrion outer membrane, endoplasmic reticulum membrane and peroxisomal proteins, by recruiting specific proteins containing a single transmembrane associated with an AKR2A-binding sequence (ABS) and subsequently binding glycolipids (e. g.  monogalactosyldiacylglycerol (MGDG) and phosphatidylglycerol (PG)) present in the membrane of the target organelle.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 2B.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Plastid, chloroplast outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PUR5_BART1
Sequence: MSNQDLINNKSKAGLTYAKAGVNIDMGNAMVEKIKPFIRATKRAGADAEIGGFGGLFDLKAAGFTDPILVAANDGVGTKLKIAIEVGHHNTVGIDLVAMCVNDLLVQGAEPLFFLDYFATGKLDPEQGAAIVSGIAEGCKQSGAALIGGETAEMPGMYAEGDYDLAGFAVGACERSMLLPSKNLTEGDIILGLSASGIHSNGFSLVRRIIEQNDLKWNDPAPFDPSNNLGVALLTPTRIYVKSLLPIMRKYEGVKALAHITGGGFLENIPRVIPSSLCAEINLSTINVPSVFSWIAKQGKIEETEMLRTFNCGIGMIIIVGQHTAEAVTQALEKNGETVTPLGILTKRQDQNKGILYRGVLHL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_ECO7I
Sequence: MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKKKR
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: HRPA_PSESY
Sequence: MTIMSSLAGAGRGVVNTIGGAAQGINSVKSSADRNAALVSNTGSTDSIDATRSSISKGDAKSAELDGTANEENGLLRESSMLAGFEDKKEALSNQIVASKIRNSVVQF
What is the function of this protein?
Major structural protein of the hrp pilus, which is a component of the type III secretion system (TTSS, Hrp secretion system) required for effector protein delivery, parasitism, and pathogenicity.  The hrp pilus functions as a conduit for protein delivery into the host cell.  Also, affects the expression of TTSS-associated genes.  Required for full expression of genes that encode regulatory, secretion, and effector proteins of the TTSS.  HrpA-mediated gene regulation apparently is through effect on the mRNA level of HrpR and HrpS (By similarity).
What are the official names of this protein?
Hrp pili protein HrpA, TTSS pilin HrpA.
What is the protein family that this protein belongs to?
Belongs to the HrpA type 1 family.
What are the subcellular locations of this protein?
Secreted. Fimbrium. Note=Extracellular and secreted via type III secretion system.
Protein: BCH_ONCHC
Sequence: MAFAMSSSLTLFQYQSFGKKPFFSRRRDFAGCSMMNPLVARCNRATEICCVVRKDGEAESLVEAENDQLEEEVMKPTSIDSFSVVLRSERKKAERRTYLVAAMASSLGFTFMAAAAVYYRFAWQMEGGAVPLTEMMGTFSLAVGSAVGMEYWARWAHRALWHTSLWHMHESHHRPRDGPFELNDVFALINAFPAVALLAFGFFHRGFFSGLCFGAGLGITLYGMAYMFVHDGLVHRRFPVGPIATVPYFQWVAAAHQIHHADKFNGVPYGLFLGHKELEEVGGMEALEREIKRGVKVFSSSPNQS
What is the function of this protein?
Nonheme diiron monooxygenase involved in the biosynthesis of xanthophylls.  Specific for beta-ring hydroxylations of beta-carotene.  Uses ferredoxin as an electron donor.
What are the official names of this protein?
Beta-carotene 3-hydroxylase, chloroplastic, OgHYB, Beta-carotene hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: HIS8_THEFY
Sequence: MSDFGHTGFSIDDLPLRDDLRGQAPYGAPQLTVKAVLNTNENPYPPSPELVEAIGRAAAEAAVGLNRYPDREATALRQALADYLGHGVDAANVWAANGSNEILQQILQAFGGPGHKALGFEPSYSMHPIIARGTATEWVSVPRTADFDVDADAAVAAVKEHEPSVVFLTSPNNPTGTALPLATVEAIAAAAPGVVVVDEAYAEFRREGTPSALSLLRTYPNVIVSRTMSKAFAMAGVRLGYLAAHPAVVDALQLVRLPYHLSTVTQAVALTALRYADELLSAVATLRAERDALVDWLRAHGFEVADSDANFVLFGRFPDRSAVFQHLLDQGVLIREVGPPEWLRVTVGTPEEMAIFREALLTATGRA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.