PharMolix/UniProtQA huggingface dataset:
Protein: PB2_I57A2
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMIPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPMTSTVHYPKIYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMIGVLPDMTPSTEMSMRGLRVSKMGVDEYSSAERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLTEDPDEGTSGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: PCKA_BACSU
Sequence: MNSVDLTADLQALLTCPNVRHNLSAAQLTEKVLSRNEGILTSTGAVRATTGAYTGRSPKDKFIVEEESTKNKIDWGPVNQPISEEAFERLYTKVVSYLKERDELFVFEGFAGADEKYRLPITVVNEFAWHNLFARQLFIRPEGNDKKTVEQPFTILSAPHFKADPKTDGTHSETFIIVSFEKRTILIGGTEYAGEMKKSIFSIMNFLLPERDILSMHCSANVGEKGDVALFFGLSGTGKTTLSADADRKLIGDDEHGWSDTGVFNIEGGCYAKCIHLSEEKEPQIFNAIRFGSVLENVVVDEDTREANYDDSFYTENTRAAYPIHMINNIVTPSMAGHPSAIVFLTADAFGVLPPISKLTKEQAMYHFLSGYTSKLAGTERGVTSPETTFSTCFGSPFLPLPAHVYAEMLGKKIDEHGADVFLVNTGWTGGGYGTGERMKLSYTRAMVKAAIEGKLEDAEMITDDIFGLHIPAHVPGVPDHILQPENTWTNKEEYKEKAVYLANEFKENFKKFAHTDAIAQAGGPLV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_VIBCH
Sequence: MTDSPVLALAKELISRQSVTPADAGCQDLMIERLKALGFEIESMVFEDTTNFWARRGTQSPLFVFAGHTDVVPAGPLSQWHTPPFEPTVIDGFLHGRGAADMKGSLACMIVAVERFIAEHPDHQGSIGFLITSDEEGPFINGTVRVVETLMARNELIDMCIVGEPSSTLAVGDVVKNGRRGSITGDLKVKGTQGHVAYPHLANNPVHKALPALAELAATQWDEGNAYFPPTSFQIPNLQAGTGASNVIPGEFDVQFNFRFSTELTDEEIKRRVHSVLDAHGLDYDVKWTLSGQPFLTDTGELLAAVVAAVEEVNHQAPALLTTGGTSDGRFIAQMGAQVVELGPVNATIHKVNECVRIADLEKLTDMYQKTLNHLLG
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CAPSD_BPS24
Sequence: MTIEKNLSDVQQKYADQFQEDVVKSFQTGYGITPDTQIDAGALRREILDDQITMLTWTNEDLIFYRDISRRPAQSTVVKYDQYLRHGNVGHSRFVKEIGVAPVSDPNIRQKTVSMKYVSDTKNMSIASGLVNNIADPSQILTEDAIAVVAKTIEWASFYGDASLTSEVEGEGLEFDGLAKLIDKNNVINAKGNQLTEKHLNEAAVRIGKGFGTATDAYMPIGVHADFVNSILGRQMQLMQDNSGNVNTGYSVNGFYSSRGFIKLHGSTVMENELILDESLQPLPNAPQPAKVTATVETKQKGAFENEEDRAGLSYKVVVNSDDAQSAPSEEVTATVSNVDDGVKLSISVNAMYQQQPQFVSIYRQGKETGMYFLIKRVPVKDAQEDGTIVFVDKNETLPETADVFVGEMSPQVVHLFELLPMMKLPLAQINASITFAVLWYGALALRAPKKWARIKNVRYIAV
What is the function of this protein?
Assembles to form an icosahedral capsid.
What are the official names of this protein?
Major capsid protein, Major head protein.
What are the subcellular locations of this protein?
Virion.
Protein: LGT_ACIAC
Sequence: MLMYPHIDPIALQIGPLAIHWYGLTYLAAFGLFMFLGTRRLRHEPYASLTGAQAWTRKDVEDILFLGVLGVVVGGRLGYCLFYKPGYYLSHPLEIFYIWQGGMSFHGGLLGVIASMVWFARSRHRPWLQVADFVAPCVPTGLAAGRVGNFINGELWGRFCDPSLPWGMVFPQSGSMLPRHPSQVYQFLMEGLLLFVLLWLYARRERRQGEVAAAFLVGYGCFRFIAEYFREPDAFLGILSLGMSMGQWLCVPMIVAGVLLWVWARRQPAR
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBIT_ECOLI
Sequence: MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFMKILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRIYALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGWKLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMVCTHMADLDYGELRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANASKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPLFKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHEYEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFGKLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRILEITPERVIDFSGNYEDYLRSKGIE
What are the official names of this protein?
Probable ATP-binding protein YbiT.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. YbiT subfamily.
Protein: UBIG_RHOPB
Sequence: MSMQSNSSDASSATVDPAEIAKFSRLSAQWWDPTGKMAPLHKINPLRLSFIRDAACRKFERNAKSLNCLSGLRMIDIGCGAGLLCEPFTRLGAQVIGVDPSATNIAAAKLHAEKSQLLIDYRCTTVEQMDPRERFDIVLAMEVIEHVTDVGAFLARCAAITKPGGLMVVATLNRNWKSFALAIVGAEYVMRWLPRGTHQWDKFVTPDELTKHLHNNKLAVTEQAGLVYNPLADKWSLSADMDVNYMVVAETAAG
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: RNPH_SYMTH
Sequence: MRQDGRLPHEMRPVRITRHYNIHAEGSVLIEVGRTRVICTATLEDRVPPFLRGRGEGWITAEYGMLPRATGQRTAREAARGRQGGRTMEIQRLIGRALRSVIDLAALGERTLIIDCDVIQADGGTRTASITGAYVAMVDALAGLRAAGLIDRLPVKDYLAATSVGVVGGVPVLDLTYEEDSRAAVDLNLVMTGSGEVVEIQGTGEERPFTRRELEELLALAESGVRRLVALQREQLGPLGVEVGAVVTEASGIGHQEPGEGAGVSLAPGGGGL
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: LTBP2_RAT
Sequence: MRAPTTVRCSGRIQRARWRGFLPLVLALLMGTSHAQRDSVGRYEPASRDANRLWRPVGNHPAAAAAKVYSLFREPDAPVPGLSPSEWNQPGQGIPGRLAEAEARRPSRAQQLRRVQSPVQTRRSNPRGQQPPAARTAHSVVRLATPQRPAAARRGRLTGRNVCGGQCCPGWTTSNSTNHCIKPVCQPPCQNRGSCSRPQLCICRSGFRGARCEEVIPEEEFDPQNARPVPRRSVEGAPGPHRSSEARGSLVTRIQPLLPPLPPPPSRTLSQTRPLQQHAGLSRTVRRYPATGTNGQLMSNALPSGPGPELRDSSQQAAHMNHLSHPWGLNLTEKIKKIKVVFTPTICKQTCARGRCANTCEKGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPVPQPDREPPGRGSQHRALLEGPLKQSTFTLPLSNQLASVNPSLVKVQMQHPPEASVQIHQVARVRGEVDPVPEDNSVETRASHRPHGSSGHSHWASNSIPARAGEAPRPPPVPSRHYGLLGQCYLSTVNGQCANPLGELTSQEDCCGSVGTSWGVTSCAPCPPRPAFPVIENGQLECPQGYKRLNLSHCQDINECLTLGLCKDSECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAVSMKQGLCYRSMVSGTCTLPLVQRITKQICCCSRVGKAWGSKCEHCPLPGTEAFREICPAGHGYAYSSSDIRLSMRKAEEEELASPVREQRQQSSGPPPGAAERQPLRAATATWIEAETLPDKGDSRAIQITTSAPHLPARVPGDATGRPTPSLPGQGIPEGPAEEQVIPSSDVLVTHGPPGFDPCFAGASNICGPGTCVKLPNGYRCVCSPGYQLHPSQDYCTDDNECLRNPCEGRGRCVNSVGSYSCLCYPGYTLATLGDTQECQDVDECEQPGVCSGGRCSNTEGSYHCECDQGYVMVRRGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYIGQSGNCVDMNECLTPGICAHGRCINMEGSFRCSCEPGYELTPDKKGCRDVDECASRASCPTGLCLNTEGSFTCSACQSGYWVNEDGTACEDLDECAFPGVCPTGVCTNTVGSFSCKDCDRGFRPSPLGNSCEDVDECEGPQNSCLGGECKNTDGSYQCLCPQGFQLANGTVCEDVDECVGEEHCAPHGECLNSPGSFFCLCAPGFASAEGGTRCQDVDECATTEPCLGGHCVNTEGSFNCLCETGFQPAPDSGECVDIDECANDTVCGNHGFCDNTDGSFRCLCDQGFETSPSGWECVDVNECELMLAVCGDALCENVEGSFLCLCASDLEEYDAEEGHCRPRVAGAQRIPEVPTEEQAAGLTGMECYAEHNGGPPCSQILGQNSTQAECCSTQGARWGETCDPCPSEDSVEFSELCPSGQGYIPVEGAWTFGQAMYTDADECILFGPALCQNGRCLNTVPGYICLCNPGYHYDAVSRKCQDHNECQDLACENGECVNTEGSFHCFCSPPLILDLSGQRCVNSTSSSEDFPDHDIHMDICWKKVTNDVCSQPLRGHHTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGIHFRPGYEYGPGPDDLPETLYGPDGAPFYNYLGPEDTVPEPPFSNTASHLGDNTPILEPPLQPSELQPPAIQNPLASFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDTALMACVDVNECEDLNGAARLCAHGHCENTEGSYRCHCSPGYVAEPGPPHCAAKE
What is the function of this protein?
May play an integral structural role in elastic-fiber architectural organization and/or assembly.
What are the official names of this protein?
Latent-transforming growth factor beta-binding protein 2, LTBP-2.
What is the protein family that this protein belongs to?
Belongs to the LTBP family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: DLG1_CAEEL
Sequence: MSHESSEKAHKAIENVEDYCQTLTRHGNEELRTNLERVITTFKSNLMHSLLDIHDLYEQTLLSERKSDAEKNMEVRRVIERLEGGPHSYNSRPAATTSTSNYNLSSTTPLISDLRDRGGFSYLNGGGLGNGLGNGLGNGLLSSPYNSSSTHYLHERQRQTSHDGTWRETTTRTVDTPSGLERRVVEHTGVIDDHGRKWELENIVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLKRRKDEAFLPIGGNFGGSTSYLRSGVTPSVSAGNLQHAIHSPSAPIHPPPPPPVHHGSLSQLSVGQYRSTRPNTSVIDLVKGARGLGFSIAGGQGNEHVKGDTDIYVTKIIEEGAAELDGRLRVGDKILEVDHHSLINTTHENAVNVLKNTGNRVRLLIQQGTGAIFNDSASQQFMPTTPILRPSSVQDYNRSQMGSQSHLSYGGPLNTSYSSQAPIAIPLEPRPVQLVKGQNGLGFNIVGGEDNEPIYISFVLPGGVADLSGNVKTGDVLLEVNGVVLRNATHKEAAEALRNAGNPVYLTLQYRPQEYQIFESKIEKLRNDVIAQSRMGTLSRKSEYVRALFDYDPSRENSVAPHRSMGFNYGDILHIINSSDDEWWTARKVHENGEETAEGVIPSKKRVEKRERLRRKQVNFNSGSQSLGRNSSTTGLENRRGSRSQLSFSRKFPFVKSTDRLNDLNEESSNVAEEPVWSYQAVEQQAINYVRPVIILGALKDRINDELVNRDPSKFSSCVPHTSRPPREGEVNGRDYYFVNKHNMEEDVKNNLFIEAGQFQNNLYGTSIQSVRDVANQGRHCILDVSGNAIRRLQSNANIQPISIFIKPSSAQQILELDSQLATNRQDDRAMSGEEAQAQYSRCHRIEQTFGDLFTQEISNVHSANDVLSKVYSIISRESQTPIWVPRH
What is the function of this protein?
Essential multidomain scaffolding protein required for normal development (Probable).  Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity).  Required for proper embryonic elongation.  Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1.  With let-413, cooperatively regulates ajm-1 localization to apical junctions (PubMed:11715019, PubMed:18411252).
What are the official names of this protein?
Disks large homolog 1, MAGUK protein DLG-1, SAP97-like protein DLG-1.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Apical cell membrane. Cell junction, adherens junction. Lateral cell membrane. Cytoplasm. Note=Localizes at the apical junctions (PubMed:11715019, PubMed:18411252). Localization at the adherens junctions requires PDZ domains, lateral distribution requires SH3 domain and is let-413 dependent (PubMed:18411252).
Protein: MYBS1_ORYSI
Sequence: MTSQAATTTTTAAAAAAWTREDDKAFENALAACAAPPPADGGAPDDDWFAALAASVPGARSAEEVRRHYEALVEDVAAIDAGRVPLPRYAGEESAAPPDGAGAAAAASKDGGHRRDERKGGGGGYDGGKSCSKAEQERRKGIPWTEEEHRLFLLGLDKFGKGDWRSISRNFVISRTPTQVASHAQKYFIRLNSMNRDRRRSSIHDITSVTAGDQVAAQQGAPITGHQATGNPAAAALGPPGMKHHHHHHPGGAPPPMPMYSAAPMGHPVAGHMVPAAVGTPVVFPPGHAPYVVPVGYPAPPAKMHQ
What is the function of this protein?
Transcription activator that binds to 5'-TATCCA-3' elements in gene promoters.  Derepress strongly the sugar-repressed transcription of promoters containing SRS or 5'-TATCCA-3' elements.
What are the official names of this protein?
Transcription factor MYBS1, Myb-related protein S1, OsMYBS1.
What are the subcellular locations of this protein?
Nucleus.
Protein: STE20_MAGO7
Sequence: MDGHSNFTQPSDTSHASHTIPSSSSSQRRRLTKKPPPSTSARHHHSSLSIDSRVDAQSLVGKRSSTSLRRAPSAPPARTPTSTHASNSSSPRNPSSSTRLNNHSPIIPAASEFAASSLSPSARDRDSDPARNDHGHQLQNNNNYYYSAFTNAHHHNQYSAASHRRSNSYGHPHGPQSSNSLTFNHSEDFIGAPFDGSAILNRIEATKASPTLGSGAFPHISNPIPVGAAAPAQYSRGSPALEQSFTFPSAAMSEKSQQVRGMEAQLPTSKRYSDETKEPKPGVLRKKSGFSGFMSGLVGTPKKPLISAPENPVHVTHVGYDSATGQFTGLPKEWQRLISESGITEKERRENPETLVNVIKFYKETTEKPAEDQVLEKFHDARPGLPSAPSAGSMISPGLAPHHYNPMSPMISPPASPRFPQVGHEGNFENPRSPPPVPKNKDVTLMPSRPAPRPPVSLPTRTAPHAPYAAKDSGIDMPPQHDDLTPTTYQPPKESQPILPEEHRSRSNSRVNGNTAYPASQQSPAVQAAYQQQLMQQQQEQALAQAQASMSGSMSRAPSKRQPQAQQPTPPQSQHQYSRPTDANGAQQTQRPQQPQIGPVPQSRPRHRSRQSNGLDVVAALKRICSEGDPREIYRSFTKIGQGASGGVYTGHERGSNRLVAIKQMNLEQQPKKDLIINEILVMKDSSHPNIVNFIDSYLCGGELWVVMEFMEGGSLTDVVTFNIMTEGQIASVCRETLLGLQHLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATINEAQNKRTTMVGTPYWMAPEVVTRKEYGRKVDIWSLGIMAIEMIEGEPPYLTESPLRALWLIATNGTPQIKDEGNMSPVFRDFLYFALKVDPDKRASAHDLLRHEFMNLCVDLSHLSPLVRAAREARAQEKARKGQ
What is the function of this protein?
MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle.  Phosphorylates histone H2B to form H2BS10ph (By similarity).  Is involved in conidiation, aerial hyphal growth and infection-related morphogenesis.
What are the official names of this protein?
Serine/threonine-protein kinase MST20.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NU4LM_STERU
Sequence: MSLTYMNMFMAFTISLLGLLMYRSHMMSSLLCLEGMMLSLFVMMTMTILNTHLTLASMLPIILLVFAACEAALGLSLLVMVSTTYGMDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRPB_BACCR
Sequence: MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMQDEAFQKELNHYLKTYIGRETPLYYAENMTKYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSNAMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDEEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RTCB_MOUSE
Sequence: MSRNYNDELQFLDKINKNCWRIKKGFVPNMQVEGVFYVNDALEKLMFEELRNACRGGGVGGFLPAMKQIGNVAALPGIVHRSIGLPDVHSGYGFAIGNMAAFDMNDPEAVVSPGGVGFDINCGVRLLRTNLDESDVQPVKEQLAQAMFDHIPVGVGSKGVIPMNAKDLEEALEMGVDWSLREGYAWAEDKEHCEEYGRMLQADPNKVSPRAKKRGLPQLGTLGAGNHYAEIQVVDEIFNEYAAKKMGIDHKGQVCVMIHSGSRGLGHQVATDALVAMEKAMKRDKIIVNDRQLACARIASPEGQDYLKGMAAAGNYAWVNRSSMTFLTRQAFAKVFNTTPDDLDLHVIYDVSHNIAKVEQHVVDGKERTLLVHRKGSTRAFPPHHPLIAVDYQLTGQPVLIGGTMGTCSYVLTGTEQGMTETFGTTCHGAGRALSRAKSRRNLDFQDVLDKLADMGIAIRVASPKLVMEEAPESYKNVTDVVNTCHDAGISKKAIKLRPIAVIKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs (By similarity).  Essential during post-implantation development of embryos.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog, 3'-phosphate/5'-hydroxy nucleic acid ligase, Focal adhesion-associated protein, FAAP.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low.
Protein: RLUC_VIBVU
Sequence: MNEIRTKVQIVDIDEDMAGQRIDNFLRNQLKDVPKSMIYRIVRKGEVRVNKKRVKAEYKLAAGDVVRIPPVTLEKKDPETAPSTKLNKVAELQDLIIYEDDHLLVLNKPSGTAVHGGSGLKFGAIEALRALRPEARFLELVHRIDRDTSGILLVAKKRSALRHLQAQFREKTVQKYYFALVMGEWKNSCKVVNAPLLKNEVNSIVRVNPNGKPSETRFKVIEKFPQATLVQASPITGRTHQIRVHTQYSGHPIAWDDRYGDRRFDAYTAQHGLNRLFLHAANIRFTHPATEQPMEINAPMGEQLEKVVQSLRTSR
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase C, 23S rRNA pseudouridine(955/2504/2580) synthase, rRNA pseudouridylate synthase C, rRNA-uridine isomerase C.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: GPMA_STREM
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERALPFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDDKLNLTAEYYLGGE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: LPXK_LEPCP
Sequence: MSGTADRLAARIERAWQDGGALQWALRPLALLMRGAVTARRALYRCGAWRTERLGVPVIVVGNRVAGGAGKTPTTLAIVAALQQAGRQPGIVSRGHGSREREARPVSADSTAQSVGDEPLLMQRRAQVPVWVGRDRVAAGRALLAAHPQVDVLVCDDGLQHLRLRRDVEVIVFDERGAGNGWLLPAGPLREPIDAPTDARQIVLYNAERPSTALPGHCARRRLAGLVELGAWWQGADARAELPPELKRQPVLASAGIGQPGRFFDSLRTLGLAIEPWPLPDHHGFDTLPWPAQTRDVIVTEKDAVKLPLQRLRAERPGLRVWVAPLLFDLPETFVSELLAALPARRPD
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: SYC_MYCBT
Sequence: MTDRARLRLHDTAAGVVRDFVPLRPGHVSIYLCGATVQGLPHIGHVRSGVAFDILRRWLLARGYDVAFIRNVTDIEDKILAKAAAAGRPWWEWAATHERAFTAAYDALDVLPPSAEPRATGHITQMIEMIERLIQAGHAYTGGGDVYFDVLSYPEYGQLSGHKIDDVHQGEGVAAGKRDQRDFTLWKGEKPGEPSWPTPWGRGRPGWHLECSAMARSYLGPEFDIHCGGMDLVFPHHENEIAQSRAAGDGFARYWLHNGWVTMGGEKMSKSLGNVLSMPAMLQRVRPAELRYYLGSAHYRSMLEFSETAMQDAVKAYVGLEDFLHRVRTRVGAVCPGDPTPRFAEALDDDLSVPIALAEIHHVRAEGNRALDAGDHDGALRSASAIRAMMGILGCDPLDQRWESRDETSAALAAVDVLVQAELQNREKAREQRNWALADEIRGRLKRAGIEVTDTADGPQWSLLGGDTK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_CAUVN
Sequence: MRLSDFDFDLPEDRIALRPAEPRDSARFLVVRPGQAVADHIVSDLPDFLRPGDALVFNDTRVIPARLSGLREGRTTGGADGTPVAVEATLHRRLAPDRWSAFMRPGKRLKVGDRVAFGGHEGRVGDLGRLDAVIAEKHDGGEVVLAFDLSGPDLDVGIAQHGDMPLPPYIAAKRGEDERDRADYQTVYAREDGSVAAPTAGLHFTPQLLERLKAKGVSLHFVTLHVGAGTFLPVKTDEVSEHRMHAEYGQVTQEIADALNAARAAGGRIVCVGTTSLRLLESATGEDGIVRPFADETAIFITPGYRFRTADVLMTNFHLPKSTLFMLVSAFAGTEAMRAAYEHAIATGYRFYSYGDSSLLFKDETC
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPSD_RHIME
Sequence: MKVMHIHFGTEGGAERFFVNLVNALHERGVEQRALIRPGRSWRKDLENGATIYEGVFRRISLSRFLLKWRMNRVLREFEPDVIMAWQLRASRFMPAHAKAFRISRLGDYPEHLGYYTNVQTLVCITPDMAAKVRELGWKRDIEVIANFTRARPAPPVARADLQTPADAFVVVGMGRFVKRKGFAGLIRAVKEVENTYLWLVGDGPEREQLEQLTDELGLRDRVRFTGWQTNAYGFLSAGDAFVINSSHEPLGNVCFEGWGAGKPTIASRAEGPSWVMTHESDALMVDCGDDVGLAAAIRRLRDDPALRERLSAGGSETLRTRFSEKAITDAYLDLFDRGVAKR
What are the official names of this protein?
Lipopolysaccharide core biosynthesis glycosyltransferase LpsD.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: YAGE_ECOLI
Sequence: MPQSALFTGIIPPVSTIFTADGQLDKPGTAALIDDLIKAGVDGLFFLGSGGEFSQLGAEERKAIARFAIDHVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWKVSEANLIRYFEQVADSVTLPVMLYNFPALTGQDLTPALVKTLADSRSNIIGIKDTIDSVAHLRSMIHTVKGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGYHQTLLQIPQMYQLDTPFVNVIKEAIVLCGRPVSTHVLPPASPLDEPRKAQLKTLLQQLKLC
What is the function of this protein?
Catalyzes the formation of 2-keto-3-deoxy-gluconate (KDG) from pyruvate and glyceraldehyde (PubMed:21294156).  May also function as a 2-dehydro-3-deoxy-D-pentonate aldolase (PubMed:23233208).  Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin (PubMed:21294156).
What are the official names of this protein?
Putative 2-dehydro-3-deoxy-D-gluconate aldolase YagE, KDG aldolase YagE, Putative 2-dehydro-3-deoxy-D-pentonate aldolase YagE.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_DESPS
Sequence: MLVLSRKLGEGIVIGDDIVLKIVEIKGGTIRIGIDAPLDKKIYRQEVYQRIIAENQEASQWSIDDLDAISSLISPQPK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.