PharMolix/UniProtQA huggingface dataset:
Protein: EX7S_ECOLI
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.  It can degrade 3' or 5' ss regions extending from the termini of duplex DNA molecules and displaced ss regions.  It can also excise thymine dimers in vitro (PubMed:4602029, PubMed:4602030, PubMed:22718974) (Probable).  Required for production of the mature 5'-end of retron Ec78 or Ec83 msDNA.  When in excess of the large subunit, counteracts the large subunit's toxicity (PubMed:26626352).
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, ExoVII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_SHIDS
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYSQEMDETISPLAANMGWTIAWEPADRDFIGREALEAQREHGTEKLVGLVMTEKGVLRNELPVRFTDVQGNQHEGIITSGTFSPTLGYSIALARVPEGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: ALG2_YARLI
Sequence: MRVAFIHPDLGIGGAERWVVDAAVGLQNLGHEVDIYTSYCNKSHCFDEVRDGLLKVTVLGDTICPHTIKGKFAIFCATFRQLHLAYELKKGPGSKVDVFVVDQLSACVPLLKLWFPKARVLFYGHFPDQLLVQNRNQMSLVKKAYRYPFDKFEEITTASADRLVVNSHFTKDMFEKTFPATKNPLVIYPCVDTDIKEQQQGLDRDMITAASQYTFLLSINRFERKKNILLAIEAFGEAQKKSSNLKLAVAGGYDFRVNENVEYLQELILACEKLKLSHISITADKYAKLLEKDTPAAVWTSIFKNDVIFFPSASNSFKNTLLHISKLLLYTPQNEHFGIVPLEGMLWKTPVLATNSGGPLETVKDNVGWTVEGKSELWAPVIDKVVHMNASDYAVLQTECVNWVNRFSQDTMASELEEAMEEVRKKAPTENVGWDYIRLGMWYSVLMTLTLSIVLLAIWP
What is the function of this protein?
Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
What are the official names of this protein?
Alpha-1,3/1,6-mannosyltransferase ALG2, Asparagine-linked glycosylation protein 2, GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase, GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: WDR24_DICDI
Sequence: MNQMNQPPNKCQTYLNLGSPLSAISSSPDSTKLIVAGRDIVKIVSVQNNEFKVTSNLRAGKTQSLNYTGNDCCWHPSLLENYRFLIATAATNGAVVIWNTVREGSKSVERVFTDHSRAVNKLAWHPEKLDCILTGSQDNTLRMWDIRDSANASKITFSPKSESIRDVQFNPSQANQFAAAFDNGTIQLWDIRKPTIAVEKITSHQGLVLTIDWHPEEKNIIASGGRDRAIRVWDFSNGKSLNNVSTISSVSRIKWRPGNKWHIASCSSIVDFQIHIWDVKKPYIPLFSFTDHRDVPTGLIWKSPSSLISCSKDSHLLLNEFQDSYKPYQHIRTTGITWNVNNELASINDKINRTQSNESLPSLSTQFPSFFASFNVPTPPPLPPLVKVEQGIMNIYTPKYQNSEIVYDEKYLFEHFAKNYRFRGESFNQLCDHNQFVSQSVNQHHISTMWSLLKLHYSNLDEIQQHKELIEQQQKEELEKLNNKKIEKQQPQKLKKQQQQQQQQQQQQQQQSQQQLQQPQLQQPQQQQQLQQPQQQLRQQNDKNIKEQQIQYIENLENKQLDSKNIIDNSNDSNQEININKEDKEDEEEDDDNTSNNLDDNQMGDIFDPSNDMMTAKEPPSSSLMEFNANDTGNDQFCNILSAEAVTPLVSLPTSISLERQKSTDNISDNNSNVHVNIKRQNQPTNNNNNNSNIDNLEKKSNKSKSTKENKESSLTDQNKQKRNDNKEKIDNNEIDNDNKDNNDDDDNDVDNIGEDNDEINNNNDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNDNNNNNNINNKKNKIKNKSIENKKDILDKKEINDEDNKSNDENDSLKILIPCFEFEEFNFQPIITDMLEACIEKGDVQTCVFIVLILGRYMDLNIEKHRLTTWFGSYIELLQRYKMWSLALEVMKYCDDQIINQASKRHTTLISACSSCGKSIPQNSIICEKCNKASSKCSICRLPVKGMWVWCQGCGHGGHLEHMKSWFIDKNQKSCPTGCTHICTPFKK
What is the function of this protein?
As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway.
What are the official names of this protein?
GATOR complex protein WDR24.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR24 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: THRC2_ARATH
Sequence: MASFSLPHSATYFPSHSETSLKPHSAASFTVRCTSASPAVPPQTPQKPRRSPDENIRDEARRRPHQLQNLSARYVPFNAPPSSTESYSLDEIVYRSQSGALLDVQHDFAALKRYDGEFWRNLFDSRVGKTNWPYGSGVWSKKEWVLPEIDDDDIVSAFEGNSNLFWAERFGKQYLQMNDLWVKHCGISHTGSFKDLGMSVLVSQVNRLRKMNKPVIGVGCASTGDTSAALSAYCASAGIPSIVFLPADKISMAQLVQPIANGAFVLSIDTDFDGCMHLIREVTAELPIYLANSLNSLRLEGQKTAAIEILQQFNWQVPDWVIVPGGNLGNIYAFYKGFHMCKELGLVDRIPRLVCAQAANANPLYLHYKSGFKEDFNPLKANTTFASAIQIGDPVSIDRAVYALKKSNGIVEEATEEELMDATALADSTGMFICPHTGVALTALMKLRKSGVIGANDRTVVVSTAHGLKFTQSKIDYHSKNIKEMACRLANPPVKVKAKFGSVMDVLKEYLKSNDK
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase 2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SERC_PSEAB
Sequence: MSKRAFNFCAGPAALPDAVLQRAQAELLDWRGKGLSVMEMSHRSDDYVAIASKAEQDLRDLLDIPSDYKVLFLQGGASQQFAEIPLNLLPEDGVADYIDTGIWSKKAIEEARRYGTVNVAASAKEYDYFAIPGQNEWTLTKDAAYVHYASNETIGGLEFDWIPETGDVPLVTDMSSDILSRPLDVSRFGLIYAGAQKNIGPSGLVVVIVREDLLGRARSVCPTMLNYKIAADNGSMYNTPATYSWYLSGLVFEWLKEQGGVTAMEQRNRAKKDLLYKTIDASDFYTNPIQPSARSWMNVPFRLADERLDKPFLEGAEARGLLNLKGHRSVGGMRASIYNALGLDAVEALVAYMAEFEKEHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_DINSH
Sequence: MSITAEEKARLIKEYATKEGDTGSPEVQIAILSSRIATLTEHFKSHKKDNHSRRGLLMMVAQRRKLLDYVKGKDEARYQKLISSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MP704_ARATH
Sequence: MEERGFMSPSLAISASYREGGSKGMSRRRSMRPSFDADNEFMNLLHGSDPVRIELNRLENEVRDKDRELSEGQAEIKALRLSERQREKAVEELTEELGKMAEKLKLIENLLESKNLEIKKINEEKKASMAAQFAAEASLRRVHAAQKDDDMPPIEAILAPLEAELKLSRQEIAKLQDDNKSLDRLTKSKEAALLDAERTVQSALAKASMVDDLQNKNQELMKQIEICQEENRIIDKMHRQKVAEVEKLMQSVRELEEAVLAGGAAANAVRDYQRKFQEMNEERKILERELARAKVNANRVATVVANEWKDSNDKVMPVRQWLEERRFLQGEMQQLRDKLAIADRAAKSEAQLKEKFLLRLRVLEESLKGPTSSSSRGTSVGRSSSNGPTRRQSLGGAETSPKITSNGSLIKRTPSSQLRSLTASASTVLKHAKGTSRSFDGGTRSLDRSKVLINGPRSNFPLNHKSSEGTSRGESPSSIKGEEESADKATNNDSVPGVLYDLLQKEVITLRKAAHEKDQSLRDKDEAIEMLAKKVETLTKAMDVEAKKMRREVAVMGKEVAAMRVVDKGQQDSKTRRLSVSKGNTAQLLSGRVSGRIGMTRSTQ
What is the function of this protein?
Plant-specific protein that interact with microtubules.
What are the official names of this protein?
Microtubule-associated protein 70-4, AtMAP70-4, 70 kDa microtubule-associated protein 4.
What is the protein family that this protein belongs to?
Belongs to the MAP70 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associated to microtubules.
Protein: UBC_RAT
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSVNTKKVKQEDTRTFLTTVSRKSPSCACSWV
What is the function of this protein?
Exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin-C.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus. Mitochondrion outer membrane; Peripheral membrane protein.
Protein: RS2_BRUA2
Sequence: MALPDFSMRQLLEAGVHFGHQTHRWNPKMAPFIYGERNNIHILDLSQTVPLLNSALKVVSDTVARGGRVLFVGTKRQASDIIADAANRSAQYYVNARWLGGMMTNWKTISNSIQRLRKLDELLAGEAQGFTKKERLNLEREREKLDRALGGIKDMGSVPDLMFIIDTNKEAIAIQEAKRLGIPVVAVIDSNCDPDQIDYPIPGNDDAARAIALYCDLIARAALDGIARQQGAMGIDVGAQVEAPVEPALQAPAEGA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: XYLG_ECOUT
Sequence: MPYLLEMKNITKTFGSVKAIDNVSLRLNAGEIVSLCGENGSGKSTLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENIFLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQVRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDGQHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKRVNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQAIAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQLKVKTSSSDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQLVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHVEKQSV
What is the function of this protein?
Part of the ABC transporter complex XylFGH involved in xylose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Xylose import ATP-binding protein XylG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NEPR1_DANRE
Sequence: MNSLEQAEDLKAFERRLTEYVSCLQPATGRWRMILIVVSVCTATGAWNWLIDPDTQKVSFFSSLWNHPFFTISCVTLIGLFFAGIHKRVVAPSIIAARCRTVLAEYNMSCDDTGKLILKPRPHIQ
What is the function of this protein?
May form with the serine/threonine protein phosphatase ctdnep1 an active complex dephosphorylating and activating lipins.  Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels.  May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics.  May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity).
What are the official names of this protein?
Nuclear envelope phosphatase-regulatory subunit 1, Transmembrane protein 188.
What is the protein family that this protein belongs to?
Belongs to the CNEP1R1 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Cytoplasm.
Protein: RM10_HUMAN
Sequence: MAAAVAGMLRGGLLPQAGRLPTLQTVRYGSKAVTRHRRVMHFQRQKLMAVTEYIPPKPAIHPSCLPSPPSPPQEEIGLIRLLRREIAAVFQDNRMIAVCQNVALSAEDKLLMRHQLRKHKILMKVFPNQVLKPFLEDSKYQNLLPLFVGHNMLLVSEEPKVKEMVRILRTVPFLPLLGGCIDDTILSRQGFINYSKLPSLPLVQGELVGGLTCLTAQTHSLLQHQPLQLTTLLDQYIREQREKDSVMSANGKPDPDTVPDS
What are the official names of this protein?
39S ribosomal protein L10, mitochondrial, L10mt, MRP-L10, 39S ribosomal protein L8, mitochondrial, L8mt, MRP-L8, Mitochondrial large ribosomal subunit protein uL10m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YKT6_DICDI
Sequence: MKVYSIGLFKVVPGNKPVLLNIVYELSSFGFFQRGSVKEVSLFVSRETVGRTNVGERVSMEHTQTQKVCHTTVDSKGLGCSVLTDSEYPGRVAHTLIRICLEEFYKVHPESEWRGLQSDVELQTPALDQLLLKYQNPETADPMMNLQKNLDETITIVKKTVEQLGQRGEKLDDLAAKSDDLSFQSKAFMNNAERMNKCCGYV
What is the function of this protein?
Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment.  Functions in endoplasmic reticulum to Golgi transport and in early/recycling endosome to TGN transport as part of a SNARE complex.  Has a S-palmitoyl transferase activity (By similarity).
What are the official names of this protein?
Putative synaptobrevin homolog YKT6, Putative prenylated SNARE protein ykt6.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Endosome membrane; Lipid- anchor; Cytoplasmic side. Note=Probably cycles through vesicles between Golgi and endosomes.
Protein: ASPA_PROM2
Sequence: MTVKRILIVSGTHGNEINPIWAVKQFNREENKFKNGIEYEYIIGNPIAYEKGCRYIDADLNRSFKASKNYDQHKNSFYETNRANFLVDEFGIDGSKPCQIAIDLHTTTANMGTSIVLYGRRLKDFCLAALLQNKFGLPIYLHEKDEAQTGFLVEAWPCGLVIEIGAVAQNFYDPKIIDRFSLIISSLREEIDKLKNNLIELPKELVVHVHQGSIDYPRDEKGDIDGLIHPERINQDWKMIKKGDPLFLDSQGIIHKYDGDQLIWPVFIGEVAYREKKIAMSYTKKEVIFSKEKWVQEFASL
What are the official names of this protein?
Probable aspartoacylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Aspartoacylase subfamily.
Protein: HIR1_ASPOR
Sequence: MHIIKPVWLTHGGERKDFEVYSCDVSPDGSRLVTAAGDGYVRIWSTEAICNTNDPAVASKPKQLASMSNHSGTIHTVRFSPNGKYLASGADDKIVCIYTLDTNPPSHATTFGSNEAPPVENWRTVRRLIGHDNDVQDLGWSYDSSILVSVGLDSKVVVWSGHTFEKLKTISIHQSHVKGITFDPANKYFATASDDRTVRIFRFTSPAPNSTAHDQMNNFVLEQTISAPFANSPLTAYFRRCSWSPDGMHIAAANAVNGPVSSVAIINRGSWDGDINLIGHEAPVEVCAFSPRLYASQPVDKQAMDNQHGAQNLVTVIACAGGDKSLSIWITSNPRPIVVAQELAAKSLSDLAWSPDGKCLYATALDGTILAVRFEDGDLGYATAMEENEKSLTKFGTNRKGAGITETPDGLLLEEKSKAGEIKGVEGRMGALMGDDQADNITNEKPALLPSNAPTPARPSSPAPDAQKSQPNGTATPSAPEPEKPDPYQAKLERLKQRPTYTKDGKKRIAPLLVSGAGAAESSLPQARLMASVSNQVKADTPQSIVDLSKPFDGLPKGGLATLLFGNKRKLAQLEEDDDGHVEKRVALASQNGATPLLTNTPDGLLPARPQPAPTGQQPTPEFIRPAVTNPCMAMSQVRLAVPKVRNQILRAIDPNGKPTEPPSASGESSKSRVDVVFEARNPSAASLTGRAVDREPVRLTLFRGEQPLWQDFLPRTVLLVTGNQSMWAAACEDGSVYIWTPAGRRLVSALVLEAQPVILECNGPWILCISAVGMCYVWNVKHLSSPHPPVSLQPALDAAIHTLGAHPSAAPAITNARINSEGRIVVAMSNGEGYSYSPSMFTWQRISEPWWAVGSQYWNTTEAPVGNLQTADAQKDKDAKAAVSAGIIPFLERNTTSETLLRGRAYFLQRLIKVLLSREGYESFESSVSIAHLENRLAAALSLGAKEEFRLYLSMYAKRIGAEGLKMKVEELLKGLIGGLFEEDEAGTAQRLQENEQEDRNWRESSETLCGWPREVLLKEVILALGKHRDLQRVTVPYAKLLGVVDGESDVGDAMET
What is the function of this protein?
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
What are the official names of this protein?
Protein HIR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRR26_HUMAN
Sequence: MESSRWDKDPPGERRPQQSQHWRARDHGARGCGPRQPTATASPRPGLWITPAHGSHTPQTNTRRTQADNIFIYESWLIHHGTQMSSVLPQPPLVRGPWHNTNSPWDSWASRGKLRVCPCRTPRLHSSGCFSSKAGTALSPSLPVPGLRPQPPFLQKPLSILAPATPPALVSPTPPKLSPGQLSPHSVNVHWGPQGHLHLPRSGTTVLHAYLQTLSSPASHQ
What are the official names of this protein?
Putative uncharacterized protein DIP2C-AS1, DIP2C antisense RNA 1, Proline-rich protein 26.
Protein: BZIP8_ARATH
Sequence: MAGSVYNLPSQNPNPQSLFQIFVDRVPLSNLPATSDDSSRTAEDNERKRRRKVSNRESARRSRMRKQRHMEELWSMLVQLINKNKSLVDELSQARECYEKVIEENMKLREENSKSRKMIGEIGLNRFLSVEADQIWTF
What are the official names of this protein?
Basic leucine zipper 8, AtbZIP8, bZIP protein 8.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSAD_MARMS
Sequence: MKVLGLETSCDETGIAIYDTENGLLAHKIYSQIAQHAEYGGVVPELASRDHVRKTLPLIDEVLQEAGMKKSELDAIAYTSGPGLVGALMAGATIGRSLAYALGIPALGVHHMEGHLLAPMLEESQPEMPFIALLVSGGHTQLVRVDGIGEYRLLGQSLDDAAGEAFDKAAKMIGLPYPGGPQIAALAKQGNPKSGLKFPRPMTDRPGLDFSFSGLKTAFLTAVHDALDNDRCDEQFKADAALAFETAVVDTLVIKCRRALEAEGLKQLIIAGGVSANQRLREQLESQLKKIKASVFYARPEFCTDNGAMIAYAGAQRLVNGQSSELSLSIRARWPLSELPPLKES
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_ACET2
Sequence: MKLFELQPAPGSKKLPKRKGRGHGTGNGKTAGRGHKGQNARSGGGVRPGFEGGQMPLYRRVPKRGFTNIFSKVYTEVNVSALNAFDDGTVVTQELLKEKGIIKKINDGVVILGNGELKKKLTVKAARFSKTAAEKIEAAGGKVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: WLS_DROPE
Sequence: MSGTILENLSGRKLSILVGSLLLCQVLCFLLGGLYAPVPAGHTNVLGSLCRENHARQNDTSFFLYSRGEGSCTQVTREEVEQDSMKLANQIVHVFQMPLPRDSRVLDYSRWQQNLIGVLQVEFGYDSSSELREPPKELQLTIDMRLAYRNKGDPDHAWKLYAHGVEHRYLDCVAAHIGSSETLYTCDMIPLFELGALHHSFYLLNLRFPLDTPKQMNLQFGHMHDLTLTAIHQNGGFTHVWLMLKTLLFPFVVGIMVWFWRRVHLLQRSPALLEYMLLYLGGALTFLNLPLEYLSLTIEMPYMLLLSDIRQGIFYAMLLSFWLVFAGEHMLIQDSHNKSTIRSRYWKHLSAVVVGCISLFVFDISERGVQLRNPFYSIWTTPLGAKVAMSFILLAGVSAAVYFLFLCYMISKVFKNIGDKRTSLPSMSQARRLHYEGLIYRFKFLMLATLLCAALTVTGFIMGQMAEGQWKWNDDVEIQLTSAFLTGVYGMWNIYIFALLILYAPSHKQWPTMHHSDETTQSNENIVASAASEEIEFSNLPSDSNPSEISSLTSFTRKVAFE
What is the function of this protein?
A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells.  In non-neuronal cells wls directs wg secretion.  The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26).  In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles.  Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip (By similarity).
What are the official names of this protein?
Protein wntless.
What is the protein family that this protein belongs to?
Belongs to the wntless family.
What are the subcellular locations of this protein?
Presynaptic cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=In non-neuronal cells, wls binds to wg in the Golgi and accompanies it to the plasma membrane where the two proteins dissociate. Wg is secreted and wls is then internalized and returns to the Golgi apparatus in a retromer-dependent manner. Wls and wg colocalize in the Golgi apparatus in wg-producing cells, and reduced expression is seen in non-producing cells. Endoplasmic reticulum expression is unchanged in wg-producing versus non-producing cells. In neuronal cells, wls is localized both pre- and postsynaptically and is transferred trans-synaptically from the pre- to the postsynaptic compartment (By similarity).
Protein: STIM1_BOVIN
Sequence: MDVCARLALWLLWGLLLHHGQSLSQSHSEKATGSGANSEESTAAEFCRIDKPLCHSEDEKLSFDAVRSIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRLAPKPPQMIRAADEALSAMTSNGSHRLIEGAHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELSSPALPSGSPHLDSSRSHSPSPPDPDTPSPAGDSRALQASRNTRIPHLAGKKAAAEEDNGSIGEETDSSPGRKKFPLKIFKKPLKK
What is the function of this protein?
Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores.  Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain.  Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1.  Involved in enamel formation.  Activated following interaction with STIMATE, leading to promote STIM1 conformational switch.
What are the official names of this protein?
Stromal interaction molecule 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single- pass type I membrane protein. Sarcoplasmic reticulum. Cytoplasm, cytoskeleton. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular Ca(2+) and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane. Associated with the microtubule network at the growing distal tip of microtubules. Colocalizes with ORAI1 at the cell membrane. Colocalizes preferentially with CASQ1 at endoplasmic reticulum in response to a depletion of intracellular calcium (By similarity).