PharMolix/UniProtQA huggingface dataset:
Protein: FLPA_SULIA
Sequence: MSEVITVKQTNMENIYECEFNDGSFRLCTRNLVSGFNVYGERLIKYEGVEYREWNAFRSKLAGAILKGLKTNPIRKGTKVLYLGAASGTTISHVSDIIELNGKAYGVEFSPRVVRELLLVAQRRPNIFPLLADARFPQSYKSVVENVDVLYVDIAQPDQTDIAIYNARFFLKVNGYMLLVIKARSIDVTKDPKEIYKAEVEKLENSNFETIQIINLDPYDKDHAIVLSRYKG
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: Y1375_HAEIN
Sequence: MKIFTSKKGQLSQLKQQKFKLEKDIQRLFEENLTLLSGYIFIRSEFSIKNSRIDTLAFDPETQAFVIIEYKRQQNSSVVDQGISYLNLMLEYKADFIVEYNEKQKVPLKRNDVDWSQSKVIFVSPAFNDFQIQATNFKDLPIELWEVNRFDNDIITLNIINKSKSAPNIKAVSNEKREEFSILKEIKVYQESDHLADKTDFIQELYEDFKQGILNLDPDIEINTRKLYIAFKKDRNIADIRIQQKNLKIWINLPYGELDDPKNLAKNVSNTGHWGNGDYEITIESTQYLEYIMSLIKQAIKD
What are the official names of this protein?
Uncharacterized protein HI_1375.
Protein: RK2_ARATH
Sequence: MAIHLYKTSTPSTRNGAVDSQVKSNPRNNLICGQHHCGKGRNARGIITARHRGGGHKRLYRKIDFRRNAKDIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGRGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPVTPWGYPALGRRTRKRKKYSETLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNMG_NITHX
Sequence: MTASFDVIVIGGGHAGCEAATAAARMGARTALVTHRLSTVGAMSCNPAIGGLGKGHLVREIDALDGLMGRVADAAGIQFRMLNRRKGPAVRGPRAQEDRKLYAAAMQAEIREAANLVVIEGEADDLIVADGRIAGIRLIDSRAFKTGAVVVTTGTFLRGLIHLGEKSWPAGRVDEAPALGLSVSFERIGFTLGRLKTGTPPRLDGATIDWAAVEMQPGDDPPEPFSVMTSRITTPQIRCGITRTMPATHEVIRANVHRSPIYSGQIRSSGPRYCPSLEDKVVRFGDRDGHQIFLEPEGLDDTTVYPNGISTSLPEEVQLAILATIPGLTKVRMIRPGYAIEYDHVDPRELDPTLQTRRLPGLFLAGQINGTTGYEEAAAQGLVAGLNAALAAGGGDPVVFDRADGYLGVMIDDLVTRGITEPYRMFTSRAEYRLTLRADNADQRLTDKGIAMGCVGAGRAVHHRAKMAALSAAKALATSLSVTPNEAARYGLSLNRDGHRRSAFELLAYPEIGWGEVAAIWPELSAIDPGVAVHLEIDAKYDVYLKRQTADVEAFRRDESLVLADVDYDAVPGLSNEARARLERARPRTVGQAGRLDGITPAALGILAAYLRREARKKTATASA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_TROW8
Sequence: MHALDALDALSIKADIPDFSPGDTVRVYVNITEGDRSRVQVFQGVVIARRGFGVRQTFTVRKISFQVGVERIFPLHSPSINRIEVVTKGSVRRAKLYYIRKLRGKKAKVKQKREL
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: MTLD_BUCA5
Sequence: MKALQFGAGNIGRGFIGKTLSESGFSVIFSDVNQNIVDAINYNREYFVKIIGSNQNKTVNIKRVSAINSNDSNIKKIISSVDLITTAVGPTALEKIALIITQGIIFKIKNQFTKPLNIIACENKIKSSSFLKQVVLKNLPIKYHDYLNKYIGFIDCSIDTIIPSINNKDDLFLTVEEFKEWIVNINQFKGAVLKIVDMKFSNNLDAFIERKLFTLNTGHAIAAYLGLIKNYKTIQDAISDKKIRVIVRSAMEESGSVLIKRYNFNKNDHLDYIEKIFLRFENPFLSDKLERIGRNPLQKLRREDRLIKPFLGAFEYNLPYSNLAKGIAAAFYYHNKNDLESIELSSSIKKQGLESTIIKICDLPVNSKEVYSIILEYNLIKKIIR
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: PSIM_PSICU
Sequence: MHIRNPYRTPIDYQALSEAFPPLKPFVSVNADGTSSVDLTIPEAQRAFTAALLHRDFGLTMTIPEDRLCPTVPNRLNYVLWIEDIFNYTNKTLGLSDDRPIKGVDIGTGASAIYPMLACARFKAWSMVGTEVERKCIDTARLNVVANNLQDRLSILETSIDGPILVPIFEATEEYEYEFTMCNPPFYDGAADMQTSDAAKGFGFGVGAPHSGTVIEMSTEGGESAFVAQMVRESLKLRTRCRWYTSNLGKLKSLKEIVGLLKELEISNYAINEYVQGSTRRYAVAWSFTDIQLPEELSRPSNPELSSLF
What is the function of this protein?
N-methyltransferase; part of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product (PubMed:28763571, PubMed:31150155).  The first step in the pathway is the decarboxylation of L-tryptophan to tryptamine by the decarboxylase psiD (PubMed:28763571, PubMed:31150155).  4-hydroxy-L-tryptophan is accepted as substrate by psiD as well (PubMed:28763571).  The cytochrome P450 monooxygenase psiH then converts tryptamine to 4-hydroxytryptamine (PubMed:28763571).  The kinase psiK catalyzes the 4-O-phosphorylation step by converting 4-hydroxytryptamine into norbaeocystin (PubMed:28763571, PubMed:31150155).  The methyltransferase psiM then catalyzes iterative methyl transfer to the amino group of norbaeocystin to yield psilocybin via a monomethylated intermediate, baeocystin (PubMed:28763571, PubMed:31150155).  4-hydroxy-6-methyl-l-tryptophancan also be converted the decarboxylase PsiD, kinase PsiK, and methyltransferase PsiM into respectively 6-methyl-norbaeocystin, 6-methylbaeocystin, and 6-methylpsilocybin (PubMed:31150155).
What are the official names of this protein?
Psilocybin synthase, Psilocybin biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
Protein: STEL6_DROME
Sequence: MSSSQNNNSSWIDWFLGIKGNQFLCRVPTDYVQDTFNQMGLEYFSEILDVILKPVIDSSSGLLYGDGKKWYGMIHARYIRSERGLIAMHRKYMRGDFGSCPNISCDRQNTLPVGLSAVWGKSTVKIHCPRCKSNFYPKSDTQLDGAMFGPSFPDIFFSLLPNLTSPLDDPRT
What is the function of this protein?
Unknown.  In males lacking the Y chromosome, its strong overexpression leads to the appearance of proteinaceous star-shaped crystals in the primary spermatocytes causing meiotic drive, possibly by interfering with normal casein kinase 2 activity.
What are the official names of this protein?
Stellate protein CG33246.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: AROL_YERPB
Sequence: MTQTIFMVGARGAGKTTIGKALAQALGYRFVDTDLFMQQTSQMTVAEVVESEGWDGFRLRESMALQAVTAPKTVIATGGGAVLSSENRAFMRDHGRVIYLRASAAVLAKRLAEDPEEAQRPSLTGKPIVEEMLDVLASREALYQDVAHHVLDGTQTPSLVVEQILQMLTGEMVK
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSME_ECOLI
Sequence: MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMSRAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCAEYDTDPQAAK
What are the official names of this protein?
Osmotically-inducible putative lipoprotein OsmE, Activator of ntr-like gene protein.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: KLRA4_MOUSE
Sequence: MTEQEDTFSAVRFHKSSGLQNEMRLKETRKPEKARLRVCSVPWQLIVIALGILISLRLVTVAVLMTNIFQYGQQKHELKEFLKHHNNCSIMQSDINLKDELLKNKSIECNLLESLNRDQNILCDKTRTVLDYLQHTGRGVKVYWFCYGMKCYYFVMDRKPWSRCKQSCQNSSLTLLKIDDEDELKFLQLVVPSDSCWIGLSYDNKKKDWAWIDNRPSKLALNTTKYNIRDGGCMFLSKTRLDNNYCDQSFICICGKRLDKFPH
What is the function of this protein?
Receptor on natural killer (NK) cells for class I MHC.
What are the official names of this protein?
Killer cell lectin-like receptor 4, Lymphocyte antigen 49d, Ly-49d, T-cell surface glycoprotein Ly-49D.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: MOBA_BACHK
Sequence: MSKWAGIVLAGGMSSRFGEPKALASWQGSTFIEHILKLMTSALQEVVVISHSHIKERVEQLVQVPVIEDIPHYKGNGPLAGIVSGMEYIEADWYAIMPCDAPNVSHEWFTILLEQTSNNYDAVVPIINGRKQPLLAAYHNRVKEKIYALLQEEKRSMGQLLSQCNVKYIAGEDIQANADWFINVNTKEEYVQAQKDLSNE
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPCP_CHOFU
Sequence: MFSSLLEAAKSSPFHGPLTPARCDAPAQGMAASAAPVGDSCEFGSTKYFALCGLGGILSCGITHTAVVPLDLVKCRLQVDADKYKNVVNGFRVSVREEGLRGLAKGWAPTFIGYSLQGLCKFGLYEVFKVQYNNMLDEETAYTYRTFVYLAASASAEFFADIALSPLEAAKVRIQTMPGVRQHTARRVAQDGPERGAWARSTRALVPLWGRQIPYTMMKFACFEKTVELLYKHVVPKPRAECSKGEQLVVTFAAGYIAGVFCAIVSHPADTVVSKLNQDKTATVGSIVGKLGFAGVWKGLGPRIIMIGTLTALQWFIYDAVKVWLRMPRPPPAEMPESMRKRLEAEGKL
What is the function of this protein?
Transport of phosphate groups from the cytosol to the mitochondrial matrix.
What are the official names of this protein?
Phosphate carrier protein, mitochondrial, Phosphate transport protein, PTP.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SSUB2_PSEU2
Sequence: MATPDLRNTPSVSPEAGQAPVQLRNVVRQFGRQRVIDGLNLDIAPGEFVALLGASGSGKTTLLRTLAGLDEIDSGELRVPVARAAVFQEPRLMPWKSAWKNVVLGLRINDAKARAEAALTEVGLAHRLNAFPATLSGGEAQRVALARGLVREPKLLLLDEPFAALDALTRIRMHQLIIDLWRKHTPAVLLVTHDVDEAILLADRVIVLADGRIADGIRVDLPRQRDSGQAGFQLIRSRLLGLLGVKVHAAVDSAPQAPEQDVTLSALRRFANAR
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: A49_VACCW
Sequence: MDEAYYSGNLESVLGYVSDMHTELASISQLVIAKIETIDNDILNKDIVNFIMCRSNLDNPFISFLDTVYTIIDQENYQTELINSLDDNEIIDCIVNKFMSFYKDNLENIVDAIITLKYIMNNPDFKTTYAEVLGSRIADIDIKQVIRENILQLSNDIRERYL
What is the function of this protein?
Plays a role in the inhibition of host NF-kappa-B activation.  Interacts with host BTRC and thereby diminishes ubiquitination of NF-kappa-B inhibitor alpha/NFKBIA.  This stabilizes NFKBIA and its interaction with NF-kappaB, so retaining p65/RELA in the cytoplasm and preventing NF-kappa-B-dependent gene expression.
What are the official names of this protein?
Protein A49R.
What is the protein family that this protein belongs to?
Belongs to the poxviridae A49 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: 3DHQ_CANTT
Sequence: MVKKVLLINGPNLNLLGTREPEKYGTTSLSDIEKAAIEQAQLKKNDSEVLTYQNNTEGFIIDRIHEARRQGVGFIVINAGAYTHTSVGIRDALLGTAIPFIEVHITNVHQREPFRHQSYLSDKAVAVICGLGVYGYTAAIEYALNY
What is the function of this protein?
Is involved in the catabolism of quinate.  Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.
What are the official names of this protein?
Catabolic 3-dehydroquinase, cDHQase, 3-dehydroquinate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: SUB2_TRIEQ
Sequence: MQLLNFGLLLLPFVAGDLAPQPEPLLAGPSDVVPGQYIVTLKEGLTSAQIRDHKKWVSSVHRANLEGFAAGASGVETEGIMKHFHIHDLNMYSGGFDEKTVEDLSRNPYVKSVHPDQHVYLAKTVTQRQARWGLGYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGINVNHVEFEGRAILGHNAIPNKPHTDEFGHGTYVAGIIAGKTYGVAKKANVVSAKAFDTGSSTYNYILETYDWIVRNITDSNRKNKAVINLSISGAKYQPFDDAVEKAFKAGIATVVAAGNDGKDAKNNTPASSPNAITVGAVRWENTRPSFSNYGKIVDIWAPGELIKSCWKGGNNATSTQSGTSAASPHVAGLVAYLMSTENLPSPSAVTARVLNLTIPNLVKDAKDSPNRVVYNGIQERKFTLPKYF
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL20_ANADF
Sequence: MRVKKGYKARRRRNRVLKLAKGFRGRRKNCYRRANQAVERALDYATRDRRQKRRDFRALWIVRINAAARQNGTTYSRLLAGLKKAGVAIDRKILADLALALPGDFAAVVKAAKA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: GBU1_KLULA
Sequence: MKVAGFILGALIQFSLTEGHVEQNENANLTEMWGEDWPFSGIQTFAHLPHHKCLIDMEKKFDIGVIGVPFDTAVSFRGGARFGPQAIRKASQRQTSMRGFNFRADINPYQDWASVVDCGDVPVTPMDNCLALKMMTAAYENLLSHESQTSDNNLPPRFVTLGGDHSIILPALRALRKTYGRLAVIHFDSHLDTWAPSKYPSFWHSDTSEFTHGSMLWIAHNEGLLTENNNIHAGLRTRLSGSSFEDYDDDDKVGFHRIEADEIMDGGIKSIVEKIKSKIPSDVPVYISVDIDVLDPSAAPGTGTMEVGGWMTRELIRIIRELEDLNLVGADIVEVSPPFDPTEITSLAGAQIAYELITNMVKKGPIDPELIKHNLELSDKLTQGQQLLGFSSPTDELNDKIQKEQFVLQA
What is the function of this protein?
Catalyzes the hydrolysis of 4-guanidinobutanoate to gamma-aminobutyrate (GABA) and urea.  Involved in an alternative, arginase-independent arginine degradation pathway via GABA.
What are the official names of this protein?
Guanidinobutyrase.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: GCH1_HAEIG
Sequence: MSKISLDALNVRNALIEKGIETPMIDPTQAKNERRESIAKHMHEVMKLIGLDLRDDSLEETPNRLAKMFIDEIFSGMDYANFPKMTKIKNQMKVSEMVQVNDITLTSTCEHHFVTIDGKVCVAYYPKDWVIGLSKINRIVSFFAQRPQVQERLTEQLLTAFQTILETDDVAVYVKATHFCVKARGIRDTNSYTVTYAYGGVFLEDRDTRKEFLATVQK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: Y5247_PSEAE
Sequence: MRIWIDADACPKAAKELVCKFALKRKLEVWMVAGQPQVKPPFACVRLVVVESGMDAADDYLVEQAEPGDLAICSDVPLADRLIKKQVAALDPRGREFDARNMGDKLAMRNLMADLRDQGQMGGGQAPYGERDRQAFANALDRLLTRLQREADLRASQPHR
What are the official names of this protein?
UPF0178 protein PA5247.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: RPPH_HAEIE
Sequence: MIDFDGYRPNVGIVICNRKGQVLWAKRCGQNSWQFPQGGINDNESAEQAMYRELHEEVGLQPKDVRLLYVSKHWLRYKLPKRLLRYDSKPMCIGQKQRWFLLQLVSDEKNINMQTTKSPEFDGWRWVSFWYPVRQVVSFKRDVYRKVMKEFASILFTDNPLIFSASREASLQHYSANKKYSQTKYTKRHFYKSRGQ
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: OR9A2_HUMAN
Sequence: MMDNHSSATEFHLLGFPGSQGLHHILFAIFFFFYLVTLMGNTVIIVIVCVDKRLQSPMYFFLSHLSTLEILVTTIIVPMMLWGLLFLGCRQYLSLHVSLNFSCGTMEFALLGVMAVDRYVAVCNPLRYNIIMNSSTCIWVVIVSWVFGFLSEIWPIYATFQFTFRKSNSLDHFYCDRGQLLKLSCDNTLLTEFILFLMAVFILIGSLIPTIVSYTYIISTILKIPSASGRRKAFSTFASHFTCVVIGYGSCLFLYVKPKQTQGVEYNKIVSLLVSVLTPFLNPFIFTLRNDKVKEALRDGMKRCCQLLKD
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 9A2, Olfactory receptor OR7-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPO4_SHESW
Sequence: MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRERRGVISTCSYEARKFGVRSAMATSYAFKLCPNLILVPGRMQVYKEVSLHIREIFSRYTPLIEPLSLDEAYLDVSECQQYKGSATLIAEAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNGQYVITPEMLPEFVKTLSLRKIPGVGKVTAEKLTSLGLNTCGDVQVYSKQELLSRFGKLGAVLIERAHGIDGRGISIDRERKSVGVETTLAKDIYTLEQCQQVMPGLIQELALRLSRSAKDRKIHKQVVKLKFSDFKQTTIEHRTEEVSVNLFYDLLTQALARQDARGIRLVGISVGLADSTLYVASTLNTQTQLDLAL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_ECOSM
Sequence: MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILIVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFDEPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_STRGG
Sequence: MHRYRSHTCGELRASDVGTDVRLSGWLHNRRDLGGILFIDLRDHYGLVQLVARPGTPGNDALAKLTKETVVRIDGKVSARGADNVNPELPTGEIEIEVTEVEVLGEAGPLPFTINTEDGVNEERRLEYRFLDLRRERMHRNIMLRSAVIASIRSKMVALGFNEMATPILTATSPEGARDFVVPSRLNPGKFYALPQAPQQFKQLLMISGFDRYFQIAPCFRDEDARADRSPGEFYQLDVEMSFVEQEDVFQPIEKLMTELFTEFGNGREVTSPFPRIPFRESMLKYGNDKPDLRAKLELVDISDVFADSGFKAFAGKHVRALPVPDTAGQSRKFFDGLGEYAVEHGAKGLAWVRVGEDGTLAGPIAKFLTETDVKTLTERLSLVPGHAVFFGAGEFDEVSKIMSAVRVEAAKRAGHFEEGVFRFCWIVDFPMYEKDEETGKIDFSHNPFSMPQGGLADLEEKDPLDILAWQYDIVCNGIELSSGAIRNHEPELMLKAFEIAGYDRETVEHEFAGMLRAFRLGAPPHGGIAPGVDRIVMLLADEPNIRETIAFPLNGNAQDLMMGAPTELDESRLRELNIQLRKPVAAKGANAPEKTAEK
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HM32_CAEEL
Sequence: MFTPEQFTKVMSQLGNFSQLGQMFQPGNVAMLQALQANGASSTPSLFPAMPSVIPSLAAPSSPTTSNLTADQIVKTCEQLETDGDVDGLFRFMCTIPPQKTQEVAGNEAFLRARALVCFHASHFRELYAILENNKFSPKYHPKLQEMWHEAHYREQEKNRGKSLCAVDKYRVRKKYPMPRTIWDGEQKTHCFKERTRSLLREWYLKDPYPNPPKKKELANATGLTQMQVGNWFKNRRQRDRAAAAKNKQNIIGVELKKTSSDMSDSDDDFEDSMTDSPSPIDEPKDLSKSHIPKLSPTLLPKMATPFDMFAAAANPLMMLNLNPALYMQFHNFFNTMRNPQIDEEENSETTVEVEADIEPPKKRSKLSIDEILNIKSEVSPSQCSPCSNESLSPKRAVKTEEVKKEDDEAAEEDSRSVKSETSEDPKHSSPKSTTSQSE
What is the function of this protein?
Transcription factor which binds a motif with the core sequence 5'-GTATCA-3' (PubMed:30890567).  Plays a role in head morphogenesis (PubMed:11476572).  Involved in embryonic development (PubMed:32814896).  Required for cell specification of the RIA interneurons (PubMed:32814896).  May cooperate with the transcription factor vab-3 and phosphatase eya-1 to repress transcription factor ets-5 expression in non BAG neuronal cells (PubMed:30890567).
What are the official names of this protein?
Homeobox protein ceh-32.
What is the protein family that this protein belongs to?
Belongs to the SIX/Sine oculis homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACDB1_METTE
Sequence: MAEFPFEISPMFEGERVRKEGMFVELGGPKSLGLELVRAADMDAIEDDKVTIVGPDLKDMEEGKTYPWAMIFNIGGELVEPDLESVVERRVHDFINYCQGIMHLNQRYDVWMRVSKDTAGKMDSFEPFGKAVMMLFKTELPFIEKMQVTFYTGKEEVEKQMELAKEIFKARDARTKDLHDEDVDVFYGCTLCQSFAPTNVCVVSPDRISLCGAINWFDGRAAAKVDPEGPQFEIAKGDLLDAVTGEYTGVNEIAKKLSSGEFDKIKLHSFFDSPHTSCGCFEVVGFYIPEVDGIGWVDREYQGMAPNGIGFSTMAGQTGGGKQIVGFLGIGVNYFYSPKFIQADGGWNRVVWLPSGLKAKIDEAIPADLKDKIATENDATDIASLKDFLEAKNHPVVATWAAAEEEEEEEEEEEEVAVAAAPMMMPAAGFQMPAMPMMSGGSGGGIKLTFKNAKITIDKLVISEKKEKK
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA.  The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex).
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit beta 1, ACDS complex subunit beta 1, ACDS complex acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the CdhC family.
Protein: RS25_ASHGO
Sequence: MPPKQQLSKAQKAAAAMAGGKKSKKKWSKKSHKDKAQHAVILDQDKLDRILKEVPTYRYVSVSVLVDRLKIGGSMARVALRHLETEGIIKPISKHSKQAIYTRATASE
What are the official names of this protein?
40S ribosomal protein S25.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.
Protein: EFTU1_YERPS
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGSARAFDQIDNAPEEKARGITINTSHVEYDTPARHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPVIRGSALKALEGDAEWEAKIIELAEALDSYIPQPERAIDRPFLLPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIIDTIKTTCTGVEMFRKLLDEGRAGENVGVLLRGTKRDDVQRGQVLAKPGSIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNVNMVVNLIAPIAMDDGLRFAIREGGRTVGAGVVAKVIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOYH_BACSU
Sequence: MEEKYETNGYDTSIVYDYKEYPDVKYGRCDNCDYTLFKSSVKSGIFLRECRRCGMKKSI
What are the official names of this protein?
Uncharacterized protein YoyH.
Protein: PRSA1_BACCR
Sequence: MKKAMLALAATSVIALSACGTSSSDKIVTSKAGDITKEEFYDQMKTQAGKQVLNNMVMEKVLIKNYKVEDKDVDKKFDEMKKQYGDQFDTLLKQQGIKEETIKTGVRAQLAQEKAIEKTITDKELKENYKPEIKASHILVKDEATAKKVKEELGQGKSFEELAKQYSEDTGSKEKGGDLGYFTAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVTDIKEQKPFDEVKGDIKKDLVQKKAQDAAFMNDLMMKEIKKADVKVDDKDLKDLFEEKKADDKKEEKK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 1.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.