PharMolix/UniProtQA huggingface dataset:
Protein: PLH20_FORAG
Sequence: MILHKSVFKSYIYVLTYFVFFSVMSCENSSVLQEAKHLTISEGFKNPLGFYDAKPTFSWELPVVEGVISQSAYQIVVASSPDLLPNNPDLWDSNKQSSSQSVWINYEGKPLVSRQKVFWQVKYWNQDDKASNWSPVQNFELGLLNNSDWKAKWIGLPTKEEGVLGSQDNIIHRPQYLRKVFELSNDVANARLYITAKGVFDVAINGEDVSDDVMPPGYTPYKKRIETITYDVTDLIESGQNTIGVEVAAGWHSGRLGWMKSYWSDTESPKILCQLEVTMKDGSKASIISDDTWKATTQGPIRISEIYDGETYDAHLEMPHWTTNSFDDKNWKAVQAFPVTSTIKLEPKRHTTVKSKIVLESKEIILKADAAIFDLQQNMVGVPLLKVPMKMGDTLKIRFAEMLSPDGTFYTDNYRSAQSTDYYIAAKEGTIEWMPKFTFHGFRYVELSGFDASKTPSKNWVKGVVQYSNFNENGSFTSSHEKLNQLQSNIVWGLRGNFFDIPTDCPQRDERMGWTGDAQVFGPTSMFNADVYKFWASWMQSVRESQYDNGGIPFVVPDVLHNGKVSSGWGDVCTIIPWKIYYRTGDVGILEENYDMMKKWVAHHQATSKDFISHMNSFADWLQPYPENGNNKGDTSHSLIGTAFFAHSAKLTAKTAEVLGKKEEQATYEALYKSVAKAFENAFFKNGKVKDVTATQTSYLLALAFDLLSEENKENAKQQLLEKISEADNHLRTGFLGTPLLSEVLDETGEIDLMYKLLFNETYPSWFYSINQGATTIWERWNSYSKAEGFNPMKMNSLNHYAYGAIGEWMYERITGIAPLQAGYKIISIAPIPKAPLTSASATLNTPYGEVASSWEIKNETLFLEVVVPPNTTAEIEIPTDNSESLKVDNENFTNGKNLKLIKNEKRKIKILAQPGTYEFQAKYSL
What is the function of this protein?
Alpha-L-rhamnosidase involved in ulvan degradation (Ref. 2, PubMed:31285597).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).  Alpha-L-rhamnosidase converts Rha-Xyl-Rha3S, the product of a sulfatase acting on Rha3S-Xyl-Rha3S oligosaccharides, to Rha and Xyl-Rha3S (PubMed:31285597).  The enzyme is able to degrade p-nitrophenyl-alpha-L-rhamnopyranoside (PNP-Rha) in vitro (Ref. 2).
What are the official names of this protein?
Alpha-L-rhamnosidase, Glycosyl hydrolase 78 family protein P20, P20_GH78, Polysaccharide utilization locus H protein P20, PUL H protein P20.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 78 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Periplasmic side.
Protein: ODO2_YEAST
Sequence: MLSRATRTAAAKSLVKSKVARNVMAASFVKRHASTSLFKQANKVESLGSIYLSGKKISVAANPFSITSNRFKSTSIEVPPMAESLTEGSLKEYTKNVGDFIKEDELLATIETDKIDIEVNSPVSGTVTKLNFKPEDTVTVGEELAQVEPGEAPAEGSGESKPEPTEQAEPSQGVAARENSSEETASKKEAAPKKEAAPKKEVTEPKKADQPKKTVSKAQEPPVASNSFTPFPRTETRVKMNRMRLRIAERLKESQNTAASLTTFNEVDMSALMEMRKLYKDEIIKKTGTKFGFMGLFSKACTLAAKDIPAVNGAIEGDQIVYRDYTDISVAVATPKGLVTPVVRNAESLSVLDIENEIVRLSHKARDGKLTLEDMTGGTFTISNGGVFGSLYGTPIINSPQTAVLGLHGVKERPVTVNGQIVSRPMMYLALTYDHRLLDGREAVTFLKTVKELIEDPRKMLLW
What is the function of this protein?
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial, 2-oxoglutarate dehydrogenase complex component E2, OGDC-E2, Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VANG1_HUMAN
Sequence: MDTESTYSGYSYYSSHSKKSHRQGERTRERHKSPRNKDGRGSEKSVTIQPPTGEPLLGNDSTRTEEVQDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFILLPPILWRDELEPCGTICEGLFISMAFKLLILLIGTWALFFRKRRADMPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDRNYQGIVQYAVSLVDALLFIHYLAIVLLELRQLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARALQKYLRITRQQNYHSMESILQHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIILSEEFIDPKSHKFVLRLQSETSV
What are the official names of this protein?
Vang-like protein 1, Loop-tail protein 2 homolog, LPP2, Strabismus 2, Van Gogh-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the Vang family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL21_ACTP2
Sequence: MYAVFQSGGKQHRVSEGQVVRLEKLEIATGEKVEFDSVLMVVNGEDVKIGAPVVAGAKVVAEVVAQGRGDKVKIVKFRRRKHSRKQQGHRQWFTEVKITGIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RECF_SHEAM
Sequence: MSLSRLSIDAFRNIDSAQLAPGAGLNLIYGHNGSGKTSILEAIYFLGMGRSFRSHLSQRVIQNDADCLTLFAVAEGQAGDSRIGLRRHRSGDTEVKIDGEKVKRLSQLAEALPIQVITPESFSLLFEGPSARRQFIDWGAFHASKQFHLAWMNTRRILKQRNQLLRDGASYEHIAFWDKELIRYALEVTAIRNDYVGSLNGVLKGIIGEFLPDVDIRVSFTRGWDSKTDFSELLQSQYARDLAIGHTVSGPHKADLRLRVGNLPAQDALSRGQLKLLVCALRIAQGKLLKQQIDKHSIYLVDDLPSELDAKHRQLLLKELIDTGAQLFVTAIEPSAIVDSLPVPPDRMFHVQAGRVTQTK
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETD_CHAVU
Sequence: MGVTKKPDLTDPILRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACTIGLAVLDPSMIGEPANPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMASVPVGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVAIWLGIGAALPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AX10A_SOYBN
Sequence: MGFRLPGIRKTSIAANQASSKSVEVPKGYLVVYVGDKMRRFLIPVSYLNQPSFQDLLNQAEEEFGYDHPMGGLTIPCKEDEFLTVTSHLNDL
What are the official names of this protein?
Auxin-induced protein X10A.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
Protein: MATA1_YEASX
Sequence: MDDICSMAENINRTLFNILGTEIDEINLNTNNLYNFIMESNLTKVEQHTLHKNISNNRLEIYHHIKKEKSPKGKSSISPQARAFLEQVFRRKQSLNSKEKEEVAKKCGITPLQVRVWFINKRMRSK
What is the function of this protein?
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion.  Transcriptional corepressor that, in a/alpha diploid cells, binds cooperatively with the ALPHA2 protein to a 21-bp DNA sequence termed the haploid-specific gene (hsg) operator, to repress transcription of haploid-specific genes and of MATALPHA1.
What are the official names of this protein?
Mating-type protein A1, MATa1 protein.
What is the protein family that this protein belongs to?
Belongs to the MATA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VE6_CRPVK
Sequence: MENCLPRSLEKLQQILQISLEDLPFGCIFCGKLLGAAEKQLFKCTGLCIVWHKGWPYGTCRDCTVLSCALDLYCHLALTAPALEAEALVGQEISSWFMRCTVCGRRLTIPEKIELRARNCTLCCIDKGQYFQWRGHCSSCKLSDQGDLGGYPPSPGSRCGECDECCVPDLTHLTPVDLEELGLYPGPEGTYPDLVDLGPGVFGEEDEEGGGLFDSFEEEDPGPNQCGCFFCTSYPSGTGDTDINQGPAGAAGIALQSDPVCFCENCINFTEFR
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RL2_YERPG
Sequence: MAIVKCKPTSPGRRHVVKVVNPELHKGKPYAPLLEKLSKSGGRNNNGRITTRHIGGGHKQHYRLVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVARDGSYVTLRLRSGEMRKVQADCRATLGEVGNAEHMLRVLGKAGASRWRGIRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: YRRB_BACSU
Sequence: MQEGDYEKAAEAFTKAIEENKEDAIPYINFANLLSSVNELERALAFYDKALELDSSAATAYYGAGNVYVVKEMYKEAKDMFEKALRAGMENGDLFYMLGTVLVKLEQPKLALPYLQRAVELNENDTEARFQFGMCLANEGMLDEALSQFAAVTEQDPGHADAFYNAGVTYAYKENREKALEMLDKAIDIQPDHMLALHAKKLIDPS
What is the function of this protein?
Could be an interacting mediator in the complex formation among RNA sulfuration components, RNA processing components, and aminoacyl-tRNA synthetases.
What are the official names of this protein?
TPR repeat-containing protein YrrB.
Protein: Y2058_DICDI
Sequence: MIKINKILSLLIILLIINCNYQFVKADAESKALDIINRYRDIARYTFFTTDGHLEKYPSGFCGGTTIEDCKWDEYIEAVILLSGITFIIAAITLIFGIIFWIFRCLCFGGCKPTHGILCPGPKYDPDIGEGYSKGRVFILKLVTLIMVAGCVAVFITSLKGNSSVTSGINNLSDTVFNKTSYTLEQLIEISNQLNETKYQQFDQKQEIQSQLTQLISDGEELESKGEDISSNAKDINNIRTKIIIVGLVFCMVVAGLIGVSALIGLPRISRAASIALVILIPFMWIVFSVHYPINSVVADICISYDTTGVQQLSNFTNPIIEQVFEGCQNDNNTISVFEDLQSLVNNLLQNATDTSCDKINDACQLAFPRYPNDNPLSVPYQQNVLDCPPTLTCSNTTLSIYLFNTTVHDFNVKCKNAPTCGDLSTCDPSILTEVMSCDWVDVSSVNSCSQGGCQYNQQVVNTTKQIMQLYDILTSLTTLWTDKVVPLIKCSYLMPFIDEVQNIVCVDEVNSLDLLIAPTAVFAILLTGLGITGILGSKRFNSKYRVKGSRSA
What are the official names of this protein?
Transmembrane protein DDB_G0292058.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SRP09_DROME
Sequence: MVFVKNWDDFEIAVENMYLANPQNCRLTMKYAHSKGHILLKMTDNVKCVQYKAENMPDLRKIEKITSNLVGHMASKE
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  SRP9 together with Srp14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (By similarity).  The complex of Srp9 and Srp14 is required for SRP RNA binding (By similarity).
What are the official names of this protein?
Signal recognition particle 9 kDa protein, SRP9.
What is the protein family that this protein belongs to?
Belongs to the SRP9 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 081L_IIV3
Sequence: MSFMVPTTFAAPQTYRLPCPTIQVQTLGPIVPSVWTIVSRYEPFRQLVVQAHLQDFLNDPQTIVTVMAPLCIPTSQTTQLVCTDASTSPTRVSVLDLSFEASLAMVQSVSVPGVLTTDTMNQSNYTAYRTHHPYRMLHVKSKPTILLNNTSHIVVGNVVASNGLVHIVDQFPMPI
What are the official names of this protein?
Putative FAS1 domain-containing protein 081L.
Protein: VPS4B_PONAB
Sequence: MSSTSPNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFLHVVKYEAQGDKAKQSIRAQCTEYLDRAEKLKEYLKNKEKKAQKPVKEGQPSPADEKGNDSDGEGESDDPEKKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMRGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRADPNHLVDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMSDMLRSLSNTKPTVNEHDLLKLKKFTEDFGQEG
What is the function of this protein?
(Microbial infection) In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (lentiviruses).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 4B.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein. Note=Membrane-associated in the prevacuolar endosomal compartment.
Protein: KAE1_PYRIL
Sequence: MLVLGIESTAHTFSIGIVKDGKILSQLGKTYIPPSGAGIHPREAAEHHARHAPAILRQLLDMLGLALSDVDVVAYAAGPGLGPALRIGAVLARALAIKLGIPLVPVHHGVAHIEVARYTTNACDPLVVLVSGGHTVITGYSDGRYRVFGETLDVAIGNAIDVFAREVGLGFPGVPAVEKCAEAADTVVAFPMPIIGQDLSYAGLVTHALQLVKSGTPLPVVCKSLIETAYYMLAEVVERALAYTKKKEVVVAGGVARSKRLREILSAASGEHDAVVKIVPDEYAGDNGAMIALTGYYAYKHGIYTTPEQSFVKQRWRLDNVDVPWFYDLCNPH
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HE71A_XENLA
Sequence: MKGTSEVKPMETHRKLLKPLVEKRRRERINNSLEKLRIFLFQTLKSEKLKNPKVEKAEILECTVQFLQSRKLLPLDREAVDKEYQSGFQHCLETTLHFMNSKPDMNGVTKELLSHQMSSCKSPSDAWSPNCAPLTKHVPSLSYQDSAPHLVSNSISISPTKTLVDSHFTYQSFKTWRPWV
What is the function of this protein?
Transcriptional repressor.  Represses transcription from both N box- and E box-containing promoters (By similarity).  Demarcates the prospective midbrain-hindbrain boundary (MHB) region in the neuroectoderm in early gastrulae embryos by repressing transcription of a number of target genes.
What are the official names of this protein?
Transcription factor HES-7.1-A, HES-related protein 1-A, XHR1-A, HES-related protein 1-A', XHR1-A', Hairy and enhancer of split 7.1-A.
What are the subcellular locations of this protein?
Nucleus.
Protein: PQQE_ACIBY
Sequence: MTEGVGLPLWLLAELTYRCPLQCPYCSNPLDYAQHKNELTTQEWFDVFDQARQMGAVQLGFSGGEPLVRQDLEQLVAHAHQLGFYTNLITSGMGLTEQRISHLKQAGLDHIQISFQASDPVVNDALAGSKHAFEQKYEMCRLVKKYDYPMVLNFVIHRHNIDQIDKIIELCLELNADTVELAICQFYGWAFLNRQGLLPTQEQLIRAERITNEYREKLKAQNHPCKLIFVVPDYYEERPKACMNGWGKIFFTVAPDGMALPCHAARQLPISFPNVREQSLSRIWYESTGFNHFRGDAWMPEGCRSCPDKDRDFGGCRCQAYMLTGNASNADPVCGKSPYHQFIEQARAESEIDSSLEKLVFRNSRNSKQFTVQQNIPVQNIVDD
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: S12A2_DANRE
Sequence: MSASPPISAGDYLSAPEPDALKPAGPTPSQSRFQVDLVTESAGDGETTVGFDSSPPEYVAEPPPDGLRDSVSGGEEAKGRFRVVNFAASSPDAAPAETAQNGDTVMSEGSLHSSTGGQQHHHYDTHTNTYYLRTFGHNTIDAVPKIDFYRQTAAPLGEKLIRPTLSELHDELDKEPFEDGFANGEELTPAEESAAKDVSESKGVVKFGWIKGVLVRCMLNIWGVMLFIRMTWIVGQAGIAYSCIIVIMATVVTTITGCSTSAIATNGFVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVELLMDSGLLMIDQTNDIRVIGTITVILLLGISVAGMEWEAKAQIFLLVILITAIFNYFIGSFIAVDSKKKFGFFSYDAGILAENFGPDFRGQTFFSVFSIFFPAATGILAGANISGDLADPQMAIPKGTLLAILITGLVYVGVAISAGACIVRDATGIESNFTLISNCTDAACKYGYDFSSCRPTVEGEVSSCKFGLHNDFQVMSVVSGFSPLISAGIFSATLSSALASLVSAPKVFQALCKDNIYPGIAIFGKGYGKNNEPLRGYFLTFGIALAFILIAELNVIAPIISNFFLASYALINFSVFHASLANSPGWRPSFKYYNMWASLAGAILCCVVMFIINWWAALLTNVIVLSLYIYVSYKKPDVNWGSSTQALTYHQALTHSLQLCGVADHIKTFRPQCLVMTGAPNSRPAILHLVHAFTKNVGLMLCGHVRISSRRPNFKELNSDMLRYQRWLLNNNSKAFYTCVVAEDLRQGTQYMLQAAGLGRLRPNTLVIGFKNDWRTGDIKEVETYINLIHDAFDFQYGVVILRLREGLDISHIQGQDDSSGMKDVVVSVDISKDSDGDSSKPSSKATSVQNSPAVQKDEDDDGKAHTQPLLKKDKKSPTVPLNVADQRLLDASQQFQQKQGKGTVDVWWLFDDGGLTLLIPYLIANKKKWKDCKIRVFIGGKINRIDHDRRAMATLLSKFRIDFSDITVLGDINTKPKSEGLTEFAEMIEPYKLREDDMEQEAAEKLKSEEPWRITDNELELYKAKGNRQIRLNELLKEHSSTANLIVMSMPLARKGAVSSALYMAWLDTLSKDLPPILLVRGNHQSVLTFYS
What is the function of this protein?
Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane (PubMed:31367042).  Plays a vital role in the regulation of ionic balance and cell volume (PubMed:31367042).  Important for maintenance of endolymph volume in the otic vesicle, probably by regulating ion homeostasis (PubMed:19633174).  Also plays a role in normal development of the swim bladder (PubMed:19633174).
What are the official names of this protein?
Solute carrier family 12 member 2, Na-K-Cl cotransporter 1.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein.
Protein: HTPG_VIBVU
Sequence: MNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNPALYENDAELGVKLSFNEEHNTLTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLSADQAVLWHSAGEGEYTVEDITKESRGTDIILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKAQALWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMNRDHKSGLKLYVQRVFIMDDAEQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERLAKNDTDKYQTFWKEFGLVMKEGPAEDYANREKVASLLRFASTEVDSAEQTVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMNYLTEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTTFKLANTPAVVVTDDFEMGTQMAKLLAAAGQAVPEVKYIFEINPNHTLVKQMADETDEEAFGRWVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA2_ARATH
Sequence: MATSTTMSHQAIGSVVSQRPFKASQFLKEPLNNVPMKFRQKRFKIEATASQISVVDNTFLSPSPSKNKPHESKKKSNEAALILIRHGESLWNEKNLFTGCVDVPLTQKGVGEAIEAGKKISNIPVDLIFTSSLIRAQMTAMLAMTQHRRKKVPIILHNESVKAKTWSHVFSEETRKQSIPVIAAWQLNERMYGELQGLNKKETAERYGTQQVHEWRRSYEIPPPKGESLEMCAERAVAYFEDNIKPELASGNNVMIAAHGNSLRSIIMYLDDLTSQEVTTLDLSTGVPLLYIFKEGKFMKRGSPVGSTEAGVYAYTKRLAQYREKLDAAATI
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2, BPG-dependent PGAM 2, PGAM 2, Phosphoglyceromutase 2, dPGM 2.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECF_ACIBS
Sequence: MHLTRLNIERVRNLKTVALHGLQPFNVFYGANGSGKTSILEAIHLLATGRSFRTHIPKNYIQYEADDAIVFAQSATEKIGMQKLASGEQLMKVNGDTVATQGQLAKLLPLQHIDPQSTEIIDHGAKPRRQLLDWLMFHVEPEFYFAWQYYSRALKQRNTLLKTRRNLSLADLEPWNKMLSNYGEILHSQRLSIVEQWNVYFQNDLSQLLPDLEIELEYSPGFHTEQGLMQDLLNQHQKDIERRYTEYGPHRADLRLKTLFGHADDVLSRGQKKLLIIALKLSQIAMLHASNKETVVLLDDLTAELDLTAQQRLIERLSQLGSQVFMTTLDRASVKKHLHDLSISYQLFSVESGQVSLAAP
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_CAMLR
Sequence: MGQKVNPIGLRLGINRNWESRWFPTKANMAENIGEDYKIRTFLKRKLYYAGISQILVERTAKKLRVTVVAARPGIIIGKKGSDVDVLRKELQNLIGKEVNINIKEERKAGASAQLAAESVATQLEKRIAFRRAMKKVIQGAQKAGAKGIKVSVSGRLGGAEMARTEWYLEGRVPLHTLRAKIDYGFAEAHTTYGNIGIKVWIFKGEVLQKGVQPEKTEESAPAKKPRRARRGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DPOE_YEAST
Sequence: MMFGKKKNNGGSSTARYSAGNKYNTLSNNYALSAQQLLNASKIDDIDSMMGFERYVPPQYNGRFDAKDIDQIPGRVGWLTNMHATLVSQETLSSGSNGGGNSNDGERVTTNQGISGVDFYFLDEEGGSFKSTVVYDPYFFIACNDESRVNDVEELVKKYLESCLKSLQIIRKEDLTMDNHLLGLQKTLIKLSFVNSNQLFEARKLLRPILQDNANNNVQRNIYNVAANGSEKVDAKHLIEDIREYDVPYHVRVSIDKDIRVGKWYKVTQQGFIEDTRKIAFADPVVMAFDIETTKPPLKFPDSAVDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKPEYPGFFTIFNENDEVALLQRFFEHIRDVRPTVISTFNGDFFDWPFIHNRSKIHGLDMFDEIGFAPDAEGEYKSSYCSHMDCFRWVKRDSYLPQGSQGLKAVTQSKLGYNPIELDPELMTPYAFEKPQHLSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDETLRKGTGTLCEMLLMVQAYQHNILLPNKHTDPIERFYDGHLLESETYVGGHVESLEAGVFRSDLKNEFKIDPSAIDELLQELPEALKFSVEVENKSSVDKVTNFEEIKNQITQKLLELKENNIRNELPLIYHVDVASMYPNIMTTNRLQPDSIKAERDCASCDFNRPGKTCARKLKWAWRGEFFPSKMDEYNMIKRALQNETFPNKNKFSKKKVLTFDELSYADQVIHIKKRLTEYSRKVYHRVKVSEIVEREAIVCQRENPFYVDTVKSFRDRRYEFKGLAKTWKGNLSKIDPSDKHARDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGATIIQMARALVERVGRPLELDTDGIWCILPKSFPETYFFTLENGKKLYLSYPCSMLNYRVHQKFTNHQYQELKDPLNYIYETHSENTIFFEVDGPYKAMILPSSKEEGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFKVFLEGDTLEGCYSAVASVCNRWLDVLDSHGLMLEDEDLVSLICENRSMSKTLKEYEGQKSTSITTARRLGDFLGEDMVKDKGLQCKYIISSKPFNAPVTERAIPVAIFSADIPIKRSFLRRWTLDPSLEDLDIRTIIDWGYYRERLGSAIQKIITIPAALQGVSNPVPRVEHPDWLKRKIATKEDKFKQTSLTKFFSKTKNVPTMGKIKDIEDLFEPTVEEDNAKIKIARTTKKKAVSKRKRNQLTNEEDPLVLPSEIPSMDEDYVGWLNYQKIKWKIQARDRKRRDQLFGNTNSSRERSALGSMIRKQAESYANSTWEVLQYKDSGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEKSSASLPNNPKTSNPAGGQLFKITLPESVFLEEKENCTSIFNDENVLGVFEGTITPHQRAIMDLGASVTFRSKAMGALGKGIQQGFEMKDLSMAENERYLSGFSMDIGYLLHFPTSIGYEFFSLFKSWGDTITILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDIKEDINFEFVYFTDISKLYRRLSQETTKLKEERGLQFLLLLQSPFITKLLGTIRLLNQMPIVKLSLNEVLLPQLNWQPTLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLDSMDYIIDVLYARKLKKENIVLWWNEKAPLPDHGGIQNDFDLNTSWIMNDSEFPKINNSGVYDNVVLDVGVDNLTVNTILTSALINDAEGSDLVNNNMGIDDKDAVINSPSEFVHDAFSNDALNVLRGMLKEWWDEALKENSTADLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKKALLQLVNEFSALGSTIVYADRNQILIKTNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLLIWMDKFNFSGLACIEIEEKENQDYTAVSQWQLKKFLSPIYQPEFEDWMMIILDSMLKTKQSYLKLNSGTQRPTQIVNVKKQDKEDSVENSLNGFSHLFSKPLMKRVKKLFKNQQEFILDPQYEADYVIPVLPGSHLNVKNPLLELVKSLCHVMLLSKSTILEIRTLRKELLKIFELREFAKVAEFKDPSLSLVVPDFLCEYCFFISDIDFCKAAPESIFSCVRCHKAFNQVLLQEHLIQKLRSDIESYLIQDLRCSRCHKVKRDYMSAHCPCAGAWEGTLPRESIVQKLNVFKQVAKYYGFDILLSCIADLTI
What is the function of this protein?
Catalytic component of the DNA polymerase epsilon complex which participates in chromosomal DNA replication (PubMed:1537345).  Required during synthesis of the leading DNA strands at the replication fork, binds at/or near replication origins and moves along DNA with the replication fork (PubMed:31488849).  Has 3'-5' proofreading exonuclease activity that corrects errors arising during DNA replication (PubMed:12124389).
What are the official names of this protein?
DNA polymerase epsilon catalytic subunit A, 3'-5' exodeoxyribonuclease, DNA polymerase II subunit A.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_MYCGE
Sequence: MVAQFNKFIILGPPGAGKGTVCKLLSKTTKLVHIASGDLFREAIKNQSVIGRKIAAIISQGGYVDDATTNQLVYEYITTNPLPNGFILDGYPRTENQLDFLNIKLTIDMVFELVVSDLNKLITRIDNRVICNNCNSVYNLLFQKPLVENSCDQCSAKLVKRSDDNKAVVKARMELYQQTIQPIHTYFFNKQLLVQIDCFLPLEEQLKTIKQFIR
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.