PharMolix/UniProtQA huggingface dataset:
Protein: RL1_XANOM
Sequence: MAQSKRVKAIAAAVAPGKAYAFEDAIKILKTATKAKFVESIDVAVRLGVDAKKSDQQVRGSTVLPAGTGKSVRVAVFAPAGAKADEALAAGAEAVGMDDLAEKMQAGDLSYDVVIATPDAMRVVGKLGTLLGPRGLMPNPKVGTVSANPGEAVKNAKSGQVRYRTDKAGIIHCTIGKASFDDEALKSNLQALLLDLVKAKPATSKGTYLQKVSVSSTMGPGVTVDQSSLSLK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: GCSH_BURVG
Sequence: MSNVPADLKYTDEHEWVRTEADGTLTVGITDHAQSTLGDIVFLELPQVGKSVNAGDAVGVVESVKAASDIYSPVSGEVVAINEEATDSPEGVNGDAYGVWLFKLKLADGASTDKLIDAAAYSKLID
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RPOC_ACICJ
Sequence: MNDLMKILGQTGQAATFDQIRIQIASPEQIRSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKFRGIICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRIATMVEMTLKDLEKVLYFENYIVLDPYTTDLKRYQLLSEDDLYAKQDEFGEDGFKAGIGAEAVKSILAGIDLEAERAIMRADLKEATSEAKRKKLVKRLKLVEAFIESGTRPEWMIMDVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQESVDALFDNGRRGRAITGTNKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYAKLEKYGLATTIKAAKRMVEKERPEVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQLEARVLMMSTNNILNPANGKPIIVPSQDIVLGLYYLSLETPAFTGVEDKEAPLFGTMGEIEHALDSGYLKLHDKIRARVVRTHPDGSRTTEVVPTTPGRMMIGQLLPKHHDVPFALVNQLLTKKKVSDVIDAVYRHCGQKESVIFCDRLMGLGFRQAAKAGISFGKDDMVIPAEKYGLLEKTQAEVKEYEAQYHDGLITAGERYNKVIDAWSRCNDEVAAAMMREISRQDPGKPTNSVWMMSHSGARGSPTQMRQLAGMRGLMAKPSGEIIEQPILSNFKEGLTVAEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIIVTADCGTERGLTMRAVMDGGEVVSSLSERILGRTAAEDVLDPADGSVIVKANELIGEIDSMHIEKLGVESVKIRSVLTCEAKVGVCAKCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQRGAEQSSVEASHDGTVTIRNRNVVSNSAGAPIVMSRNCEIALNDASGRERARFRVPYGARLLVDEDQTVTRGQKLAEWDPYTLPIITERAGLVEYADLLEGVTLVERVDEVTGLTSKVVVDYKQSAKGADLRPRLILKDERGEVLRLANGAEARYFLSPDSILSVENGASVHAGDVLARIPREGSKTRDITGGLPRVAELFEARRPKDHAIIAETDGRVEFGKDYKAKRRIIVKNDETGEETEYLVPKGKHVSVQEGDYVHRGDPLVDGPRVPHDILRVLGVEALSEYLINEIQDVYRLQGVKINDKHIEVVVRQMLQKIEITEPGDTTYLVGELVDRIEFDEENERRLRAGERPAGGLPVLQGITKASLQTLSFISAASFQETTRVLTEAATAGKTDQLLGLKENVIVGRLIPAGTGSVMSRLRSIAAGRDRSTLAATRPALPARDEVSAD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RWDD4_RAT
Sequence: MGANEDQEMELEALRSIYEGDESFRELSPVSFQYRIGEDGDPKAFLIEISWTETYPQTPPVISMNAFFNNTISSAVKQSILAKLQEAVEVNLGTAMTYTLFEYAKDNKEQFMENHHPGSSTTPIANIISVETPSAAPSSKKKDKKEQLSKAQKRKLADKTDHKGELPRGWNWVDVVKHLSKSGSKDDE
What are the official names of this protein?
RWD domain-containing protein 4.
Protein: BNI4_YEAST
Sequence: MSDSISDSKSSELLNSTFYSSTSINTLDHARTFRNSLILKEISDQSLNSSIKPCESVLDRDVESSVLQRSFGESNARDSEVQTVNMTTSPSLSALADILNERSKYADQKTRKAQNIESSIIEEEEEAEEQNNSINYHEDITGSRLSVREEANENLAMTSPNLIDIDGSNSIQVAPLSLPSFEEPDFLSTPRVKPDSQGPRSKVSTRRTILERDNNLPVKREENTIINSETESTTHSAPFLKEDPKPSPPSSKLYNPKVRLNKAEARKYTDSSAQRTTSAGSVLEDTSMHKKKKSIFSFLKKKEPKPVIGNNSVTNEKNKMSSSSTFSMNIQTSLKTPEKLKKKSHSSSSIFNSFLKGKIETSDSPRKEPMRQKKRTPKSKDKKQDTEQIIDAASVLSTESPLLRKNHDDTPVKIDHVTRSIDQRKPTPLNMDLILGGDKQINTPLQEHVREDDDAKNDLQLPTKDNFLSLDYEAPSPAFSKHDTGEVLFPKFLDNHEVDSIVSLERTRSTKSNKRSSMNSQRRSLTDTLSIKAQSEGMFITEASSVVLSTPDLTKSPASSILKNGRFEYSDNFSREHSYEGTTNEDFLDIKDDSGPLKKDDIFLESIEQKFDQLVMASDEEKTEVERDVPKPREEPLKKDSERQSVFADDDNELISDIMEFASFINFGDDDLNLDLDLGDTTASYATETPEPVGNDEVNRSGTFDTRNNKEDSYKERETQSYSAAGATTYGDERQGQLHTFEQDGSEINDNEFENEDFNKHIEQPIEVTPRNNAYLPEFEPNRPVSMSFKGLKAPRMNTSFIDSMTPDSPVKSDLTSLGEVYVNSNNDQGVRFSSQIILYDTYGEFEYDRHPEISTCNQLTPQLAQMIKLELNELKSAMEVHDDSRCYTHFY
What are the official names of this protein?
Protein BNI4.
Protein: COBQ_CHRVO
Sequence: MSAKTIMIQGATSDAGKSALATGLCRLLARRGVKVAPFKPQNMALNSAVTADGGEIGRSQAVQAQACGVEPHTDMNPVLLKPNSHTGSQVIIQGRAIGNMEARGYHGYKPVAMKAVLASHARLAAQYQCIVAEGAGSPAEINLRDGDIANMGFAEAVDCPVILVADIERGGVFAHLAGTLALLSESERARVVGLVINRFRGDPSLLKTGVDWLERHTGKPVLGVLPYLYDLHLEAEDSMGLDKPGGAVGGGDKLRVAAPAAPRVSNHTDFDPLRLHPQVEFTLVRAGQAIPPADLIVLPGSKNVLADLAWLRAQGWDEALRRHLRYGGKVLGICGGLQMLGKKLHDPDGLEGEPGSGDGLGWLDMETTLAPEKRLTRMRGRLTLGDAEAAGYEIHMGVSQGPALARPAVRFDDGSADGARSEDDQIFATYLHGVFDEPAACQAILRWAGLKEPEALDYPALREANIDKLADMLERHLDLEPIRRWLPETR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: PDE4A_MOUSE
Sequence: MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERSEPERSPHRPIERADAVDTGDRPGLRTTRMSWPSSFHGTGTGGGSSRRLEAENGPTPSPGRSPLDSQASPGLMLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVASEAHGEDLIVTPFAQVLASLRNVRSNFSLLTNVPIPSNKRSPLGGPPSVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTPRQRPFQQPPPAAVQQAQPMSQITGLKKLVHTGSLNINVPRFGVKTDQEDLLAQELENLSKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYHSAIRQSPSPTLEEEPGVLSDPALPDKFQFELTLEEEDEEDSLEVPGLPCTEETLLAPHDTRAQAMEQSKVKGQSPAVVEVAESLKQETASAHGAPEESAEAVGHSFSLETSILPDLRTLSPSEEAQGLLGLPSMAAEVEAPRDHLAAMRACSACSGTSGDNSAVISAPGRWGSGGDPA
What is the function of this protein?
Efficiently hydrolyzes cAMP.
What are the official names of this protein?
cAMP-specific 3',5'-cyclic phosphodiesterase 4A.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
Protein: OPR11_ORYSJ
Sequence: MSSTAPLLTPYKMGRFDLSHRVVLAPLTRQRSYGNVPQPHAILYYQQRTTKGGLLIAEATGISDTAQGYKDTPGIWTKEQVEAWKPIVDGVHAKGGIFFCQIWHVGRVSNNTFQPNGQAPISSTNKSLKPAVRANGIDVATFSTPRRLETDEIPFVVNDYRVAARNAIEAGFDGVEIHGAHGYLIDQFLKDQVNDRSDKYGGSLENRCRFALEVVQAVTDEIGADKVGIRLSPFASYSEAADSNPEALGLYMANALNKFGILYCHMVEPRMVKLGEKFETPHSLRPIRDAFKGTFIAAGGYNKEDGNKAVSTGYTDLVAYGRLFLSNPDLPERFEIDAPLNKYNRETFYISDPVIGYTDYPFLPSDV
What is the function of this protein?
Putative oxophytodienoate reductase that may be involved in the biosynthesis or metabolism of oxylipin signaling molecules.
What are the official names of this protein?
Putative 12-oxophytodienoate reductase 11, OPDA-reductase 11, OsOPR11.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
Protein: HSLV_THISH
Sequence: MEQFRGTTIVCVRRNGRVALGGDGQVTLGNTVMKGNARKVRRLYGDKVLAGFAGGTADAFTLFERFEGKLEKYSGNLTRAAVELAKDWRTERALRRLEALLAVADKETSLLITGNGDVIEPEDNLIAMGSGGPFAQAAARALLDNTELSAREIAERALNIAADICIYTNRHLTIEEM
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TL33_SPIOL
Sequence: VLYSPDTKVPR
What are the official names of this protein?
Thylakoid lumenal 33.6 kDa protein.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: PTMCB_STRR6
Sequence: MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGYLPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGSIATVGAITGSSVPMFIGAMVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLTGAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFLLEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAMAGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNILLGVLVAAVVSFLIAALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMGSSAMGASILRDKVKKAGLELPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHVSVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQGTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNSQFLIVDSLVTTPEYDKMAARMYK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
PTS system mannitol-specific EIICB component, EIICB-Mtl, EII-Mtl.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PMRA_ASPFU
Sequence: MSRSATPALPLHNAQASRPSSRAPVTGVRSPSTSTSTYSLLGPEETAERLQTSLLHGLTPAEAEIRLLRDGPNELPHEEPEPLWLRFLKQFKETLILLLLASAAISFFMGNYDDAVSITLAVTIVVTVGFVQEYRSEKSLEALNRLVPHHAHLIRDVPPSSAPLMNNSTTAALGPDIELEDLASKSPSSASAAIKASSTVLASELVAGDLVLFTTGDRIPADIRITAATDLTIDESNLTGENEPVAKYPEALRSTKAAVSHSPKIVSPPRSPFYDAPASGAVGADIRLNEQHNIAFMGTLVRSGYGQGIVIGTGAKTEFGSISVSLQEIESPRTPLQLSMDRLGQELSYISFGVIALIVVIGLVQGRKLLEMFTIGVSLAVAAIPEGLPIIVTVTLALGVLRMAKRGAIMRRLPSVETLGSVNVVCSDKTGTLTLNHMAVTKMWHFDCPEPFEVHNDISSLTSGPAARTVLRIGNIANNARLSRVSANSPASASSAAVLSSTVDRASGAVKSRWVGQPTDVAILDLLDTFGEDDLRDRISRRVAETPFSSERKWMGVIIGSAQNDAPSFTGANNVAYIKGALEQVLTRCDTYLTKDGREVILDEPRRHTVRQAAEHMASEGLRVLAFASGAVRDTAGGGRVFGSRTSTPLSITSQGDEDDRYTGLVFAGLVGMNDPPRKDVHKSIRRLMAGGVRVIMITGDAESTAVAIAKKLGMPVRDSPGSRPVLTGQDLDRMSTADLAQAISTTSIFARTSPEHKMKIVRALQSRGDVVAMTGDGVNDAPALKKADIGIAMGKLGTDVAKEAADMILTDDDFSTILRAIEQGKGIFYNIQNFITFQLSTSVAALSLVLLSTLLGFKNPLNAMQILWINILMDGPPAQSLGVEPVDPTIMNRPPRSRTARVLTRPLIQRVLTSAFMIMLGTLAIYVYEMGDADDLSTPGKRSRVVTAHDTTMTFTCFVLFDMFNALTCRSESKSVLRGELPLFGNKMFNYAVLGSLFGQACVIYVPFFQRIFQTEPLNAAHLLKLLCVSSTVFWVDEGRKYLNAVKRRRAVGVGYSVNV
What is the function of this protein?
Magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytosol to the Golgi apparatus lumen (By similarity).  Involved calcium homeostasis and both conidiation and polarized growth (PubMed:20097742, PubMed:32487759).  Its activity is coupled to the unfolded protein response (UPR) and Ca(2+) import into the Golgi apparatus is important for virulence, cell wall biosynthesis, and resistance to antifungal compounds that inhibit Ca2+ signaling (PubMed:20097742).
What are the official names of this protein?
Calcium-transporting ATPase pmrA.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
Protein: RL333_STRP6
Sequence: MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVTFTEVK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MURC_NEIMB
Sequence: MMKNRVTNIHFVGIGGVGMSGIAEVLHNLGFKVSGSDQARNAATEHLGSLGIQVYPGHTAEHVNGADVVVTSTAVKKENPEVVAALEQQIPVIPRALMLAELMRFRDGIAIAGTHGKTTTTSLTASILGAAGLDPTFVIGGKLNAAGTNARLGKGEYIVAEADESDASFLHLTPIMSVVTNIDEDHMDTYGHSVEKLHQAFIDFIHRMPFYGKAFLCIDSEHVRAILPKVSKPYATYGLDDTADIYATDIENVGAQMKFTVHVQMKGHEQGSFEVVLNMPGRHNVLNALAAIGVALEVGASVEAIQKGLLGFEGVGRRFQKYGDIKLPNGGTALLVDDYGHHPVEMAATLAAARGAYLEKRLVLAFQPHRYTRTRDLFEDFTKVLNTVDALVLTEVYAAGEEPIAAADSRALARAIRVLGKLEPIYCENVADLPEMLLNVLQDGDIVLNMGAGSINRVPAALLALSKQI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RASD1_MOUSE
Sequence: MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQILDTKSCLKNKTKENVDVPLVICGNKGDRDFYREVEQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGDHGDAFGILAPFARRPSVHSDLMYIREKTSVGSQAKDKERCVIS
What is the function of this protein?
Small GTPase.  Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similarity).
What are the official names of this protein?
Dexamethasone-induced Ras-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. RasD family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, perinuclear region. Nucleus.
Protein: FMT_FERNB
Sequence: MRILFMGTPEFAASYLDFLIQKKFNVVAVISQKDKPRGRGQKLLPTPVKEVAQKYGIPVFQPSKLNEEGLEIIENYRPDIGIVVAYGRLLRKPFLDAIPLYNVHTSLLPKYRGPAPMQRAIENGERVTGVTIFKISEGMDEGDIALQRAFELEECEPFGSVYEKFIKYGTELLQEFLRNYPVTLTPQDHSKATYAPKIEKKDLYVDFSKPAVEVRNKIRAYDPTPGVRTFLNDIEVKLYGACEIESNSQENIEPGTVVRIEKQSGDGVIKTIDGLLHIKYIQFPGKNKITFLSAKNGGLIKEGMVFRNLD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: DEF10_ARATH
Sequence: MKLSLRLISALLMSVMLLFATGMGPVEARTCESPSNKFQGVCLNSQSCAKACPSEGFSGGRCSSLRCYCSKAC
What is the function of this protein?
Confers broad-spectrum resistance to pathogens.
What are the official names of this protein?
Defensin-like protein 10, Low-molecular-weight cysteine-rich protein 72, Protein LCR72, Plant defensin 2.6.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL5_RUTMC
Sequence: MSRLQEQYKNEILPALQKELDMSNPMQVPKIEKITINMGLGSALGDKKVLQSALKEMSLISGQKPLICNARKSVASFKLREGNPIGCKVTLRKERMYEFLDRLINIAIPRIRDFRGFKATAFDGRGNYNMGITEQITFAEIDFEKVTRILGMDIAITTTAKSDEEAKKLLVMFKFPFKG
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: COWN_CERSK
Sequence: MNDQTPDRYVTFLGLDCDAKADRLMDMLAVRIQEDDSRWVGYFRQKLAEKERMATDNLHFVGSQINSLYSYFEELEDADALDLLWHLEHNCC
What is the function of this protein?
Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO).  Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.
What are the official names of this protein?
N(2)-fixation sustaining protein CowN, CO weal-nitrogenase.
What is the protein family that this protein belongs to?
Belongs to the CowN family.
Protein: RS7_THEFY
Sequence: MPRKGPAPKRQLMTDPVYGSPLVTALINKVLRDGKRSLAQSIVYNALEGAREKTGQDPLVILKRAIDNVKPTLEVRSRRVGGATYQVPVEVRASRSTTLALRWLVQYARLRREKTMTERLMNELVDASNGLGAAVKRREDTHKMAESNKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL6_BRASB
Sequence: MSRIGKKPVTVPSGVTATVDGQTVKMKGPKGQLQFIVHDDVDVKFENGQVRVAPRSETKRARSLYGTARAQIANLVEGVTKGFEKKLEITGVGYRAAMQGKNLQLALGYSHDVVYQIPEGITIAVPKPTEITVTGIDPQRVGQVAAEIRAYRPPEPYKGKGVKYAGEFIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: END4_SYMTH
Sequence: MKLGCHISISKGFPQAVENAHRLGCEAFQFFTKNPRGFKGKSADPEAAARGRALMAEYGLVAVAHAPYITNLSTPDPELQAISIASLKQDLENAEAYGAIGCVCHMGKHVGEGEAYGRARMVETLNRLLEAYTGSCPLLLENTAGMGSELGTHLEELMEVRSRVEQPERIAFCFDTCHAFAAGIYRPEDWEDFVAHARAIGYWGLLRAVHLNDSKFDHGSRKDRHANLGKGFLGEAGIATLLRSGAFEGLPVVLETPVKDEAEYGPEIAYARSLLQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: COX7C_PANPA
Sequence: MLGQSIRRFTTSVVRRSHYEEGPGKNLPFSVENKWSLLAKMCLYFGSAFATPFLVVRHQLLKT
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7C, mitochondrial, Cytochrome c oxidase polypeptide VIIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIc family.
Protein: GEDJ_ASPTN
Sequence: MPSLKDWVVAGLVPMTIASSTSRLPSNCTNGPSSRRCWQDGFDIWSDYTDPKVAPPGKLVEYDLTVTQVTISPDGYERLGTVFNGQYPGPLIEADWGDTLRITVHNNLTNGNGTAVHWHGIRLFETNWIDGVPGVTQCPIPPGESQVYEFRATQYGTSWYHSHFSLQYSNGLYGPLVIHGPSSSDWDVDLGPWTLTDWYHEDAFTLNWISLAGQLAPIPVSTLLNGKGTYDCDPGLDPACTGKQEYFETTFQQGTKYKMAIVNTATLLTYTFWIDGHNFTVIEADFVPVEPYSTNVLNVGMGQRYEIVVEANADRTQGSSFWIHAHYCDIPDVIPNNKVGIIRYDESDTSEPATPPLSEQHRDFGCSDPSLGDLVPVVKKTVGPRVNQIGPHDYLTIGEQGKIPTPWEKDPRVHLWTIKNTAMYVDWQTPSLEKLTADHDEEFPPETVPVTLDFDTGEWVYFLLTSNYSLEDVVTPRNLTPSVHPIHLHGHDFAILAQGKGPFTPDIAPQLDNPPRRDVVDVDIGGYAWIAFEVDNPGAWLLHCHLQYHASEGMALQYIEQPSKIKPLIENAGVLNDFGNRCASWKRYYNAVDIPNDRPQDDSGI
What is the function of this protein?
Dihydrogeodin oxidase; part of the gene cluster that mediates the biosynthesis of geodin, an intermediate in the biosynthesis of other natural products (PubMed:7665560, PubMed:19549600, PubMed:24009710).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) gedC (PubMed:12536215, PubMed:19549600).  The atrochrysone carboxyl ACP thioesterase gedB then breaks the thioester bond and releases the atrochrysone carboxylic acid from gedC (PubMed:19549600).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodinanthrone (PubMed:24009710).  The next step is performed by the emodinanthrone oxygenase gedH that catalyzes the oxidation of emodinanthrone to emodin (PubMed:1810248).  Emodin O-methyltransferase encoded probably by gedA then catalyzes methylation of the 8-hydroxy group of emodin to form questin (PubMed:1444712).  Ring cleavage of questin by questin oxidase gedK leads to desmethylsulochrin via several intermediates including questin epoxide (PubMed:3182756).  Another methylation step probably catalyzed by methyltransferase gedG leads to the formation of sulochrin which is further converted to dihydrogeodin by the sulochrin halogenase gedL (PubMed:24009710).  Finally, the dihydrogeodin oxidase gedJ catalyzes the stereospecific phenol oxidative coupling reaction converting dihydrogeodin to geodin (PubMed:7665560).
What are the official names of this protein?
Dihydrogeodin oxidase, DHGO, Geodin synthesis protein J.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: CRVP_DRYCN
Sequence: MIAFIVLLSLAAVLQQSSGTVDFASESSNKKDYRKEIVDKHNALRRSVKPTARNMLQMEWNSHAAQNAKRWADRCTFAHSPPHTRTVGQLRCGENIFMSSQPFAWSGVVQAWYDEVKKFVYGIGAKPPGSVIGHYTQVVWYKSHLLGCASAKCSSTKYLYVCQYCPAGNIRGSIATPYKSGPTCGDCPSACVNGLCTNPCKYEDAFTNCNELAKETKCKTEWIKSKCPATCFCHTEII
What is the function of this protein?
Blocks olfactory (CNGA2) and retinal (CNGA1) CNG channel currents.  Does not affect neither depolarization- nor caffeine-induced contraction of smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein, CRVP, Cysteine-rich secretory protein, CRISP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: EIF3G_YEAST
Sequence: MSEVAPEEIIENADGSRSIITYKIEDGVKYKITQKVKEVKVLEKVHKSVAERKNWHKYGSEKGSPAGPSAVTARLGEEVELRLSRNWKQAEEERIQKEKASLTKTGLQCRLCGNDHMTMNCPFKTILSELSALEDPATNEGGVEAASEEKAGQVGGAGSIPGQYVPPSRRAGARDPSSDAYRDSRERDDMCTLKIMQVNENADENSLREELLFPFAPIPRVSVVRNKETGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPKVKE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation (Potential).  Binds to the 18S rRNA but non-specifically (PubMed:10085088).
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Translation initiation factor eIF3 p33 subunit, eIF3 p33.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.