PharMolix/UniProtQA huggingface dataset:
Protein: DXR_EDWI9
Sequence: MKTLTILGSTGSIGTSTLAVVRANPGAFRVVALVAGKNVDVMLQQCREFSPRYVCMANEGAAAALRQRLFECGLGTIAVMSGEHAACELAALDEVDQVMAAIVGAAGLLPTLAAIRANKRVLLANKEALVTCGRLFMEALSHSQAQLLPIDSEHNAIFQSLPTAVQQQLGFACLREHGVTRIVLTGSGGPLRQLPLADFDAVTPTQACAHPNWSMGRKISVDSATMMNKGLEYIEARWLFNASAEEMEVIIHPQSVIHSMVRYRDGSVIAQLGNPDMCTPIAHAMAYPDRVPSGVAPLDFCRMGSLSFEAPDMARYPCLQLAIEAFAEGQAATTALNAANEIAVAAFLDGRLRFTDIARLNRRVVEQLRCAEPDCVEAVLVIDSAARQLAQTLSARFSR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: SPIKE_CVPMI
Sequence: MKKLFVVLVVMPLIYGDNFPCSKLTNRTIGNHWNLIETFLLNYSSRLSPNSDVVLGDYFPTVQPWFNCIRNNSNDLYVTLENLKALYWDYATENITLNHKQRLNVVVNGYPYSITVTTTRNFNSAEGAIICICKGSPPTTTTESSLTCNWGSECRLNHKFPICPSNSEANCGNMLYGLQWFADAVVAYLHGASYRISFENQWSGTVTLGDMRATTLETAGTLVDLWWFNPVYDVSYYRVNNKNGTTVVSNCTDQCASYVANVFTTQPGGFIPSDFSFNNWFLLTNSSTLVSGKLVTKQPLLVNCLWPVPSFEEAASTLCFEGAGFDQCNGPVLNNTVDVIRFNLNFTTNVQSGKGATVFSLNTTGGVTLEISCYNDTVSDSSFSSYGEMPFGVTDGPRYCYVLYNGTALKYLGTLPPSVKEIAISKWGHFYINGYNFFSTFPIDCISFNLTTGDSDVFWTIAYTSYTEALVQVENTAITKVTYCNSYVNNIKCSQLTANLNNGFYPVSSSEVGLVNKSVVLLPSFYTHTIVNITIGLGMKRSGYGQPIASTLSNITLPMQDNNTDVYCIRSDQFSVYVHSTCKSSLWDNVFKRNCTDVLDATAVIKTGTCPFSFDKLNNYLTFNKFCLSLSPVGANCKFDVAARTRTNDQVVRSLYVIYEEGDNIVGVPSDNSGLHDLSVLHLDSCTDYNIYGRTGVGIIRQTNRTLLSGLYYTSLSGDLLGFKNVSDGVIYSVTPCDVSAQAAVIDGTIVGAITSINSELLGLTHWTTTPNFYYYSIYNYTNDRTRGTAIDSNDVDCEPVITYSNIGVCKNGALVFINVTHSDGDVQPISTGNVTIPTNFTISVQVEYIQVYTTPVSIDCSRYVCNGNPRCNKLLTQYVSACQTIEQALAMGARLENMEVGSMLFVSENALKLASVEAFNSSETLDPIYKEWPNIGGSWLEGLKYILPSDNSKRKYRSAIEDLLFAKVVTSGLGTVDEDYKRCTGGYDIADLVCAQYYNGIMVLPGVANADKMTMYTASLAGGITLGALGGGAVAIPFAVAVQARLNYVALQTDVLNKNQQILASAFNQAIGNITQSFGKVNDAIHQTSRGLATVAKALAKVQDVVNTQGQALSHLTVQLQNNFQAISSSISDIYNRLDELSADAQVDRLITGRLTALNAFVSQTLTRQAEVRASRQLAKDKVNECVRSQSQRFGFCGNGTHLFSLANAAPNGMIFFHTVLLPTAYETVTAWAGICALDGDRTFGLVVKDVQLTLFRNLDDKFYLTPRTMYQPRVATSSDFVQIEGCDVLFVNATVSDLPSIIPDYIDINQTVQDILENFRPNWTVPELTFDIFNATYLNLTGEIDDLEFRSEKLHNTTVELAILIDNINNTLVNLEWLNRIETYVKWPWYVWLLIGLVVIFCIPLLLFCCCSTGCCGCIGCLGSCCHSICSRRQFENYEPIEKVHVH
What is the function of this protein?
S1 region attaches the virion to the cell membrane by interacting with host ANPEP/aminopeptidase N, initiating the infection.  Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion.  S2 region belongs to the class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
What are the official names of this protein?
Spike glycoprotein, S glycoprotein, E2, Peplomer protein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses spike protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly.
Protein: BIOB_RHOJR
Sequence: MTSAPVQTDILALAREQVLERGDALNESQVLEVLQLPDDRLEELLALAHDVRMKWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKSGASEFCIVAAVRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLAAMGVHRYNHNLETSKSHFPNVVTTHTWDERWNTLRMVREAGMEVCCGGILGMGESLEQRAEFAANLAELEPDEVPLNFLNPRPGTPFGDLEVLPASEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGNYLTTLGRPAEQDLDLLVDLQMPIKALNDTL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ATPE_STRA3
Sequence: MAQLTVQVVTPDGIRYDHHASLITVRTPDGEMGILPGHINLIAPLIVHQMKINRSHQEGVDWVAVNGGIIEVNEDQVTIVADSAERARDIDLNRAERAKERAERALEKAQTTQNIDEMRRAEVALRRAINRISVGKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYNC_MOUSE
Sequence: MSSEVIRGTAEMVLAELYVSDREGNDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENERWDVISKSQMKNIKKMWHREQMKNDSREKKEAEDNLRREKNLEEAKKIIIKNDPSLPEPACVKISALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLSDDLCQCYNGVVLSTESSVAVYGTLNLTPKGKQAPGGHELSCDFWELVGLAPAGGADNLINEESDVDVQLNNRHMMIRGENMSKILKARSMITRCFRDHFFDRGYCEVTTPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEFTHVEAECPFLTFEDLLNRLEDLVCDVVDRVLKSPVASIVYELNPNFKPPKRPFRRMNYSDAIEWLKEHDVKKEDGTFYEFGDDIPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDPRLTESVDVLMPNVGEIVGGSMRSWDSEEILEGYKREGIDPAPYYWYTDQRKYGTCPHGGYGLGLERFLSWILNRYHIRDVCLYPRFLQRCRP
What is the function of this protein?
Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn).  In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells.  Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells.
What are the official names of this protein?
Asparagine--tRNA ligase, cytoplasmic, Asparaginyl-tRNA synthetase, AsnRS, Asparaginyl-tRNA synthetase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_CLONN
Sequence: MRIGMGYDVHKLCENRKLILGGIEIPYELGLLGHSDADVLIHAIMDSLLGAAALGDIGKHFPDTDNKYKGISSMLLLKEVGKLLNENSYEIINIDATIIAQKPKMAPYIKDMIKNIASALCINENQVNIKATTEEGLGFTGEGLGISSQSICLINEK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PSD_HAEDU
Sequence: MSLKSYSTPTYWQRVKVACQYLFPQLPITRLAGWLAEQKWGMVTHFIIRIFAKQYNVNLAEAEKTNPADYTTFNEFFLRPLKENARPINQDDQAVCLPADGKISELGQINENRLLQAKGHYFTLETLLANDEEMAESFKNGSFITTYLSPRDYHRVHMPCDATLKKMIYVPGDLFSVNSFLAEHIPNLFARNERVICEFETAFGPMVQILVGATITASISTVWAGIINPPRSKDVVEYNYQTTGETAIHLKKGDEMGAFRLGSTVINLFPQATVELVSHLQAGVETRMGERFAKIIK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PEPT_STACT
Sequence: MKEELIDRLKRYAEIDTQSDPDSESTPSTEKQRDLLNLLKQELEELGLQTDIDDNGYLFATLESNIANEVPTVGFLAHVDTSHDFNASNVKPQIIENYDGKPIQLGDTDRELNQEVFPAMKSVEGHTLMITDGTSLLGADDKAGVAEIMTALTYLVEHPEVKHGRIRVAFTPDEEIGRGPHKFDVKRFDADFAYTMDGSQYGELQFESFNAAEATITCHGVNVHPGSAKDVMVNAIKLGERFDSMLPEDEVPEKTEGYEGFFHLMNFNGTTEKAQLKYIIRDHDRERFEARKACLLEIRDQINTVYNNDPVEVDMYDQYHNMAEKINEVPEVIEVPKRVFKKLGIEPNTEPIRGGTDGSQLSFMGLPTPNIFTGCDNFHGPFEYASIDVMERAVEVILGIAEEIAQPTDK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1278_HAEIN
Sequence: MTQLTREQVLELFHQRSSTRYYDPTKKISDEDFECILECGRLSPSSVGSEPWKFLVIQNKTLREKMKPFSWGMINQLDNCSHLVVILAKKNARYDSPFFVDVMARKGLNAEQQQAALTKYKALQEEDMKLLENDRTLFDWCSKQTYIALANMLTGASALGIDSCPIEGFHYDKMNECLAEEGLFDPQEYAVSVAATFGYRSRDIAKKSRKGLDEVVKWVG
What are the official names of this protein?
Putative NAD(P)H nitroreductase.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: TIG_ROSDO
Sequence: MQVTETLNEGLKRGYAIKVTAAELDAKVNEKLAEAQPEVEMKGFRKGKVPMALLKKQFGQKVMGEAMQESIDGAMNDHFTSSGDRPAMQPEVKMTNENWKEGDDIEVSMSYEALPDIPDVDFSAIELERMTVKADDAAIDEALGSLAETAQNFENRKKGSKAKDGDQIVMDFLGKVDGEAFDGGAAEDYPLVLGSNSFIPGFEEQLVGVKAGEEKAVTVTFPENYQAENLAGKEAVFECTVKEVKKPVPAEIDDELAKKFGAEDLAALKGQIAERLEAEYAGAARAIMKRSLLDALDDIVDFDLPPSLVSAEAGQIAHQLWHEENPDVQGHDHPEITPTEEHTKLAERRVRLGLLLADIGQKAKVEVTDAEMSQAIMNQARQYPGQERQFFEFVQQNQQMQQQMRAPIFEDKVVDHVFAGAKVTEKEVSKDDLQKAVEALEEE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: SYS_METPB
Sequence: MHDIRAIRENPEAFDRDLERRGLSPLSAELIALDDARKGAVSAAQAAQERRNALSKEIGAAKKAKDEARAAELMAEVARLKEEAPGLDAAQAQAAKVLDERLAAIPNQPKADVPLGADEHGNVEYRRFDSSRARLAEGRQHFELGEATGLMDFEAAAKLSGSRFVVLKGPLARLERALGQFMLDLHTGEHGYTEVVPPVLVRDEAMFGTAQLPKFRDDQFAAGDGFWLIPTAEVPLTNLVRENILAEDELPLRFTALTPCFRAEAGAAGRDTRGMLRQHQFNKVELVSITAPEKSAEEHERMLACAEAVLQKLDLTYRVMTLCTGDMGFASQKTYDIEVWVPGQQTYREISSCSVCGEFQARRMNARYRAKEGRGVGFVHTLNGSGVAVGRALIAVMENYQNPDGSVTIPSVLQPYMGGLNRIEGPNT
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKR1_MACMU
Sequence: MGNCLHPAELSPSTQNSSQLNSDLWNFSYDGNDSFPDVDYDANLEAAAPCHSCNLLDDSALPFFILVSVLGILASGTVLFMFFRPLFHWQLCPGWPVLAQLAVGSALFSIVVPILAPGLGNTRSSALCSLGYCVWYGSAFAQALLLGCHASLGPKLGAGQVPGLTLGLSVGLWGVAALLTLPITLASGASGGLCTPAYSMELKALQATHAVACLAVFVLLPLGLFGAKGLKKALGMGPGPWMNILWAWFIFWWPHGVVLGLDFLVRSKLLLLSTCLAQQALDLLLNLAEALAILHCVATPLLLALFCHQATRTLLPSLPLPEGWSSHLDTLGSES
What is the function of this protein?
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis.  Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor.  Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines.  Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC.  May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels (By similarity).
What are the official names of this protein?
Atypical chemokine receptor 1, Duffy antigen/chemokine receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
What are the subcellular locations of this protein?
Early endosome. Recycling endosome. Membrane; Multi-pass membrane protein. Note=Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane (By similarity).
Protein: MSRA_NAUPA
Sequence: MPKAVFGGGCFWCLDAVFRKVDGVRDVVVGYAGGRRPNPNYEQVCTGVTGHAEVVEIDYDENTVSYDELLDIFFKIHDPTQLNRQGNDVGTQYRSIILYLDEEQKEKALKKIEELKKEGLNVVTEVKPLEIFYPAEKYHQNYFAKNPHQPYCMYVVAPKVEKYLKIKNENKKT
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: SYR_CUPTR
Sequence: MLPVQTSNLAAAFTDAVRALAPADATLPAVTFERPKVAAHGDLACNVAMQVARALKSNPRELAQRIVAAVEADARAQGLVAGMDIAGPGFINLRLTPSAKADVLRAVLNEGDHYGARERGVHGQVLVEFVSANPTGPLHVGHGRQAALGDALANLLSWQGWHVHREFYYNDAGVQIQTLALSVQARARGLKPGDASWPEAAYNGDYIADIAADFLAGKTVSASDGEPVTASGNVEDIDSIRKFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYSDGRVDAAVQSLIDKGKTYESEGALWLRTTDDGDDKDRVMKKSDGTYTYFVPDVAYHTTKWERGFTKVINVQGSDHHGTIARVRAGLQGLDIGIPQGYPDYVLHKMVTVMKNGEEVKISKRAGSYVTVRDLIEWSNGGDETIRGCLEQGVADWPAHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIFESWGGADWESRLAELAGADLSAVTGADASAQALALGRRLAEFPDMLAAAAAELAPHAVAFYLRDLAGDFHAFYNADRVLVDDEAVKRARLALLAATRQVLRNGLAVIGVSAPRRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN6A_BRAOL
Sequence: KGRTVEIFNSFELLLDPTTQTLDRSFLEKKQELYKKMLNSRIRVLHQYLAAKFNTAYERNTRRGGR
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 6a, Signalosome subunit 6a.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SAT4_STACB
Sequence: MNGIYALQQTFVKFSLLALYHRLFWVNRHFVRSVWLVGIVQGCWGIAILLVHIFLCTPMEKIWTPWMVEGTCVDVNTLFAIYEALNSVLDFIVAGLAIWMLPSLQIRKSTRWHLAGLFVLGAFSGFIGIIKIVEAYDSAQRNFQAVIWNVVQMSISIICCCAPIYRSILPKMGMSSIPSWASWSLRGSSRRSKAVASTADGTSKFSMRSYQGEGKAGGTSVSGNWINLDGSSQRALAWVDAESHGKDQSTYQDIPMGRMKVERSVEVI
What is the function of this protein?
Part of the satratoxin SC1 cluster involved in the biosynthesis of satratoxins, trichothecene mycotoxins that are associated with human food poisonings (PubMed:25015739).  Satratoxins are suggested to be made by products of multiple gene clusters (SC1, SC2 and SC3) that encode 21 proteins in all, including polyketide synthases, acetyltransferases, and other enzymes expected to modify the trichothecene skeleton (PubMed:25015739).  SC1 encodes 10 proteins, SAT1 to SAT10 (PubMed:25015739).  The largest are SAT8, which encodes a putative polyketide synthase (PKS) with a conventional non-reducing architecture, and SAT10, a putative protein containing four ankyrin repeats and thus may be involved in protein scaffolding (PubMed:25015739).  The putative short-chain reductase SAT3 may assist the PKS in some capacity (PubMed:25015739).  SAT6 contains a secretory lipase domain and acts probably as a trichothecene esterase (PubMed:25015739).  SAT5 encodes a putative acetyltransferase, and so, with SAT6, may affect endogenous protection from toxicity (PubMed:25015739).  The probable transcription factor SAT9 may regulate the expression of the SC1 cluster (PubMed:25015739).  SC2 encodes proteins SAT11 to SAT16, the largest of which encodes the putative reducing PKS SAT13 (PubMed:25015739).  SAT11 is a cytochrome P450 monooxygenase, while SAT14 and SAT16 are probable acetyltransferases (PubMed:25015739).  The SC2 cluster may be regulated by the transcription factor SAT15 (PubMed:25015739).  SC3 is a small cluster that encodes 5 proteins, SAT17 to SAT21 (PubMed:25015739).  SAT21 is a putative MFS-type transporter which may have a role in exporting secondary metabolites (PubMed:25015739).  The four other proteins putatively encoded in SC3 include the taurine hydroxylase-like protein SAT17, the O-methyltransferase SAT18, the acetyltransferase SAT19, and the Cys6-type zinc finger SAT20, the latter being probably involved in regulation of SC3 expression (PubMed:25015739).
What are the official names of this protein?
Satratoxin biosynthesis SC1 cluster protein 4.
What is the protein family that this protein belongs to?
Belongs to the SAT4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYGB_STRPS
Sequence: MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAIQTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVEDIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVHTLTVLLDEEEFDLDFLDIKGGRVSRGHRFLGQETKIQSALSYEEDLRKQFVIADPCEREQMIVDQIKTIEAERGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTSMKEHQRYFVVRDQDGKLLPNFISVRNGNAEHLENVIKGNEKVLVARLEDGEFFWREDQKLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIYKFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAVLAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYALKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEVSKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQLKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG06A_GAHVM
Sequence: MLSQNGTADPRYISYPGCIDCGPTFHLETDTATTRNGTSSFGDRIRSFCERARSLISNFVTWRSRNESCEVLAEIPQEKEVESTL
What are the official names of this protein?
Uncharacterized gene 6a protein.
Protein: ARC2B_XENLA
Sequence: MILLEVNNRIIEEILTLKFENAAAGNKPEVVEVTFADFDGVLYHVSNPNGDKAKVMISISLKFYKELQEHGADEVLKNVYGNFLVAPESGYNVSLLYDLEALPSNKDSVIHQAGMLKRNCFASVFEKYFKFQEEGKEGEKRAVIHYREDETMYVEAKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTSANARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFAAR
What is the function of this protein?
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity).  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (Probable).  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 2-B.
What is the protein family that this protein belongs to?
Belongs to the ARPC2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Protein: ACCD_ENTFA
Sequence: MALFKKKNYIRINPNRAHANDASKKPSVPDNMWAKCPSCKRTLYTKEMGAEKICPHCGYSFRIGAWERLAITVDEKSFHNWDSELVTKDPLNFPGYLEKIEKMQEKTGLDEAVLTGEATIEGQAVAIGIMDANFIMGSMGTIVGEKITRLFERATEKHLPVVIFTASGGARMQEGIFSLMQMAKISAALQRHNKAGLLYLTVLTDPTTGGVTASFAMDGDIILAEPQSLIGFAGRRVIEQTIRQELPDDFQKAEFLLEHGFVDQIVPRNLLRQRLSDLLRLHSLEGWR
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_NEIMF
Sequence: MSLNIETKKVAVEEISAAIANAQTLVVAEYRGISVSSMTELRANARKEGVYLRVLKNTLARRAVQGTSFAELADQMVGPLVYAASEDAVAAAKVLHQFAKKDDKIVVKAGSYNGEVMNAAQVAELASIPSREELLSKLLFVMQAPVSGFARGLAALAEKKAGEEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RHIC_RHILV
Sequence: MTATLRAFGWLAAFALTVTFAQGAAAEEQQKGKVGAKPVETGVVIRGVTLAGPVGNPGTSTGKTCDFSGEPVDPSGRLEGASVNCRPNGNQANTTPGLPARFNAYCMINAPVKSARLIQAARPENANHCDLSGITPKDATGQFGGAVWR
What is the function of this protein?
May be involved in plant-microbe interaction.
What are the official names of this protein?
Protein RhiC.
What are the subcellular locations of this protein?
Periplasm.
Protein: M810_ARATH
Sequence: MYLLLYVDDILLTGSSNTLLNMLIFQLSSTFSMKDLGPVHYFLGIQIKTHPSGLFLSQTKYAEQILNNAGMLDCKPMSTPLPLKLNSSVSTAKYPDPSDFRSIVGALQYLTLTRPDISYAVNIVCQRMHEPTLADFDLLKRVLRYVKGTIFHGLYIHKNSKLNVQAFCDSDWAGCTSTRRSTTGFCTFLGCNIISWSAKRQPTVSRSSTETEYRALALTAAELTWSSASRSRDPSAMNTN
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00810, ORF240b.
What are the subcellular locations of this protein?
Mitochondrion.