PharMolix/UniProtQA huggingface dataset:
Protein: EX7L_LACLM
Sequence: MTEYLSVSTLTKYLKAKFERDPYLERVYLTGEISNFRRRPNHQYFALKDEGAVIQATMWAGQFRKLDFELEEGMKVLAIGRISIYPPSGSYSINIESLVPDGVGALALKFEQLKKKLAAEGLFDQRWKQNLPQFSKKIAVVTSPSGAVIRDIITTVQRRFPMSQIVLYPTKVQGAGAAEEISGNIRRANERGDFDVMIIGRGGGSIEDLWGFNEEIVVRAIFESRIPIISSVGHETDVTLADFVADSRAATPTAAAELATPNTKIDLINWANEQESRLFNRLTHLIKIRRERLEKLSQSVVFRQPERLYDGHVQKLDRLCERLTVLTENKVANMKHRYELSANRLIPTYSKIVESKKNKTEQLYQSLLLLDISKIKARGFSLITDENGKIIKSVSDVKKGQALDVELTDGQVKVEVK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_VIBA3
Sequence: MAKQPTRARKRVRKQVADGVAHIHASFNNTIVTITDRQGNALAWATAGGSGFRGSRKSTPFAAQVAAERCGEMAKEYGLKNLEVMVKGPGPGRESTVRALNAAGFRITNIVDATPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TEB_EUPCR
Sequence: MPKQKAAKKDHYQYSDLSSIKKEGEEDQYHFYGVVIDASFPYKGEKRYVVTCKVADPSSVAKGGKLNTVNVVFFSQNFEDLPIIQRVGDIVRVHRARLQHYNDAKQLNVNMYYRSSWCLFIGNDKEAPLEPKVENEDGTNNYFSYTPYNFSGKSFTQEGHETKILKDLKKWSKDYFSNNDVVEQVKKADIETAMKNKTDFDLLAKVTEISDNDQYTNTVSLNDSTGQTWTGHLFKRKFPHLVKGDVLRIKSVSAKEDNSLIFSSHSNILKFFSFSSIHKKLKSSISSDTHIKTCVTKIDKAAHNKMDITPLKKLFFNPKKSEKLFRSQFSVLKVDTKNLEDYVGAFDGKKWHSYKGKKTPKDAELRWNIKLIVTDYKNQQDDKAYMIHLDDNSFFKGINPANWSNAATKKKAEKAFSVLTNNKVNYVDAILERDKKNYHIRHTQFK
What is the function of this protein?
May function as protective capping of the single-stranded telomeric overhang.  May also participate in telomere length regulation during DNA replication.  Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
What are the official names of this protein?
Telomere-binding protein 51 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the telombin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: AMPA_CHLTB
Sequence: MVLLYSQASWDQRSKADALVLPFWMKNSKAQEAAVVDEDYKLVYQNALSNFSGKKGETAFLFGNDHTKEQKIVLLGLGKSEEVSGTTVLEAYAQATTVLRKAKCKTVNILFPTISQLRFSVEEFLTNLAAGVLSLNYNYPTYHKVDTSLPFLEKVTVMGIVSKVGDKIFRKEESLFEGVYLTRDLVNTNADEVTPEKLAAVAKGLAGEFASLDVKILDRKAILKEKMGLLAAVAKGAAVEPRFIVLDYQGKPKSKDRTVLIGKGVTFDSGGLDLKPGKAMITMKEDMAGAATVLGIFSALASLELPINVTGIIPATENAIGSAAYKMGDVYVGMTGLSVEIGSTDAEGRLILADAISYALKYCNPTRIIDFATLTGAMVVSLGESVAGFFANNDVLARDLAEASSETGEALWRMPLVEKYDQALHSDIADMKNIGSNRAGSITAALFLQRFLEDNPVAWAHLDIAGTAYHEKEELPYPKYATGFGVRCLIHYMEKFLSK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECB_CHLPN
Sequence: MKPFNIFDSNSSIQGKFFLEASAGTGKTFTIEQIVLRALIEGSLTHVEHALAITFTNASTNELKVRIKDNLAQTLRELKAVLNSQPASLPTYLDINCNVKQIYMQVRNALATLDQMSLFTIHGFCNFVLEQYFPKTRLIHKNPALTHSQLVLHHITNYLKQDLWKNVLFQEQFHLLAVRYNVTSKHTSSLVDKLLASYTQPISSYFSSRVERLEQISLWHQQIYNSLLEIPKQVFLDQLTAHISGFKKQPFSILDDLHHFVDLLYTSETHSSLFSFFKIAETFNFKHRLARYKPCAAFTVLENMSWVERTLEFCNLDRIFNTLLVDLQEYLKQNYTPWLSPDESVFALEKLLSSSEAQPVVQALREQYQLVLIDEFQDTDKQQWSIFSNLFISPKFTGSLFLIGDPKQSIYEWRSADLPTYLTAKSSFSEDKQLQLVNNYRSTPKLMEAINQIFGKISPFLEIPGYLPIEYHALNPQSSETFENPPHAPIHFFFYETIKDQALWIFSEALRLQKEQKIPLGNMVVLVSDSNQAFELISYATIPVSFSKNKSIFHLTETHILTTALLEAILHPENYEKISKILFSSLFGLSLDEVTTKKEDFTIYFQSLHSYISHHGLLATFYRVMTTQGNVLFSSPRGDLIFQEMEKLCGYLDTISSYPYHQLLHLKNFSETGRWEEELAISSYSEDLETLKITTIHSSKGLEYDIVFCPGIEKSKKNKSSSELLREMYVACTRAKKQLYLPISTQPPSLQRSSALTNYVKLEGTQSSAYDLAIHLHQEHPDLFSYSLPKDHGHATTVLNLPLLETFALKVTPPKTIFSFSSTKFLLDTHKDSQSIPYSKLPISKQQLPLGEKTGILIHKILESIQFSLLQDTEYLMSTIMRFIKHTHLEGFEETILKLLSKTFFSPLTFSSQTFSLSQVLPNKIFRETSFLFLENQELWQGVIDLFFEHEGKYYIIDWKTSFLGETNSDYSKSNLSIYIKQEKLDYQGRIYVKAVRKFLNQFEIDDDVELGVIFIRGIDTQGNGFFALNSSEDIPNFNPKAIQKCQAYH
What is the function of this protein?
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair.  Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity.  Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction.  Cuts ssDNA a few nucleotides 3' to the Chi site.  The properties and activities of the enzyme are changed at Chi.  The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair.  Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination.  In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
What are the official names of this protein?
RecBCD enzyme subunit RecB, Exonuclease V subunit RecB, ExoV subunit RecB, Helicase/nuclease RecBCD subunit RecB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: PNP_NEIG1
Sequence: MFNKYVKTFQYGNQTVTLETGEIARQAAAAVKVSMGDTVVFVAVTTNKEVKEGQDFFPLAVDYLERTYAAGKIPGGFFKREGKQSEKEILTSRLIDRPIRPLFPEGFYHDIQIVAMVVSVDPEIDSDIPAMLGASAALVLSGVPFAGPIGAARVGYINGVYVLNPTKAELAKSQLDLVVAGTSKAVLMVESEAKILPEDVMLGAVVYGHDQMQVAINAINEFADEVNPEVWDWKAPETNEELVAKVRGIAGETIKEAFKIRQKQARSAKLDEAWNAVKEALITEETDTLAANEIKGIFKRLEADVVRSQILDGQPRIDGRDTRTVRPLNIQTGVLPRTHGSALFTRGETQALAVATLGTSRDEQIIDALSGEYTDRFMLHYNFPPYSTGEVGRMGAPKRREIGHGRLAKRALLAVLPKPEDFSYTMRVVSEITESNGSSSMASVCGGCLSLLSAGVPLKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTTEGVTALQMDIKIQGITKEIMQIALAQAKEARLHILDQMKAAVAGPQELSAHAPRLFTMKISQDKIRDVIGKGGETIRSITAETGTEINIAEDGTITIAATTQEAGDAAKKRIEEITAEVEVGKVYEGTVVKILDNNVGAIVSVMPGKDGLVHISQIAHERVRNVGDYLQVGQVVNVKALEVDDRGRVRLSIKALLDAPVREENAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATL1_ARATH
Sequence: MSTFSGDETAPFFGFLGAAAALVFSCMGAAYGTAKSGVGVASMGVMRPELVMKSIVPVVMAGVLGIYGLIIAVIISTGINPKAKSYYLFDGYAHLSSGLACGLAGLSAGMAIGIVGDAGVRANAQQPKLFVGMILILIFAEALALYGLIVGIILSSRAGQSRAE
What is the function of this protein?
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase subunit c1, V-ATPase subunit c1, V-type proton ATPase 16 kDa proteolipid subunit c1, V-ATPase 16 kDa proteolipid subunit c1, Vacuolar H(+)-ATPase subunit c isoform 1, Vacuolar proton pump 16 kDa proteolipid subunit c1, Vacuolar proton pump subunit c1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: IF1_HAES1
Sequence: MAKEDCIEMQGTILETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVEMTPYDLSKGRIIFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINA_ALKOO
Sequence: MRAEIISIGTELLLGEIINTNAQYIARELASLGIDVYHQSVIGDNETRLSEAFETAFKRSDVVITTGGLGPTKDDMTKETAASFFGKKLIPHEESLKKIEAYFKGRGLNVNEGNRKQGYFPEGSIVLPNPNGTAPACIIEENNKKLILLPGPPREMIPLFETQVLPYLKKFQDKFFSFKVLNVCGIGEGEMEEAIMDIVDHQTNPTVAPYAKPNGLTLRIAASGHTQKEADELIHPMEEQIRERLGLNIYGEDDISLEEIVAKILIEKKLTISIAESCTGGFLSGRLVNYPGISSVFMEGIVTYSNESKVKYLGVNPQTIEKYGAVSEEVAREMAEGICKSAHTNIGLSVTGLAGPSGGREDKPIGLVYVGICINGVTTVKELNLGGSRNRIRSLATTYTLDLLRREVLNRSL
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: ATG3_CRYNB
Sequence: MNNPLLAIQSQYWAVRDYLSPVLRESKFKEHGRITPEEFVAAGDFLTFKFPVWQWEKGESSRARDFLPPDKQYLVTRNVPCLRRATAVDYTNADEDAEKLLSFLDDAEEAPGPDDDWVATHINRSPPHRPTDMDEIPDIPDSPTTAPTREMAGLNVSSGGKLEEDEIPDIDDIPDMDEEGLEDLEDDAAVRIVHPSEAEVNSTAGKNLLQVRTYDCIISYDKHYQTPRFWLFGYDEHKNPLTPAQVFQDVPADHAFKTMTMESFPHSGAQLASVHPCKHASVMKKFIDRMEAAQGPAPTAEPETISSTSGTSGSAGGKEEKEKKKKWGLGSMVRKVTGGSVPKVEKDKDEVVTGVPVDFYLVIFLKFIASIVPTIEVDSTTSTAL
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8.  The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of ATG8.  The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme ATG3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_BRUO2
Sequence: MDARIFQDNDDTSLPVNQASVTRIHKKPGKAEAEAAVRTLLLWVGEDPDREGLLETPKRVAKAYQELFGGYSGSPEEVLGTTFEEVAGYDDMVLVKDISFFSHCEHHMVPIIGKAHVAYLPEGRVVGLSKIARVVDIFARRLQTQESITAQIADSIQRILKPRGVAVMIEAEHMCMAMRSIRKQGSSTITTTFTGDFKEKADQQVRFMTLIRT
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: TXS4E_CUPSA
Sequence: GFGMLFKFL
What are the official names of this protein?
Short cationic peptide-4e, SCP-4e, Cupiennin 1-like peptide-1g, Short cationic peptide-1g, SCP-1g, Truncated variant of Cupiennin 4 family.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 08 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SERC_ACIAC
Sequence: MNRPYNFSAGPAAIPAEVLQQAASEMLDWHGSGMGVMEMSHRGKEFISIYEQAEADLRELLAVPQDFRILFMQGGGLAENAIVPLNLSRAATVDMVVTGSWSQKSLKEARKYASEVHVAASAEDSGFTTLPDPASWQLSRGASYLHLCSNETIHGIEFHELPDLRALGSDAPLVIDFSSHVASRPVDWSRVGLAFGGAQKNLGPAGLTLVVVREDLLGHALPACPSAFDYKVVAENQSMFNTPPTWGIYIAGLTFQWLKRQREGDLSGIAAMEQRNIAKARLLYNFIDQSQFYVNKVSPNARSRMNIPFFLRDETRNEAFLAGARERGLLQLKGHKSVGGMRASLYNAMPLAGVEALVAYMQEFEQRSA
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_MESM1
Sequence: MKKDYYEILGLTKSASKDEIKKAYRTLAKTYHPDVNKETNAEEKFKEITEAYEILNDDVKREQYNQFGHAAFDPNAGGFGGQNPFTNAEGFSGFSDFSGFGSIFTDFFGGFGNSQRANPNRAQRGEDRHAVIKISFIDSVLGKEIVEPLEKFETCNTCNGSGAKSQSDIITCTQCSGMGEQIKITKTFLGQMQQNVICSKCNGIGKEIVEKCLICKGKTHTKTTKNITIKIPAGIQNGQTLRVENYGNAGLNGGSNGNLILSIKVSPHKHFVRKNNDIILRLPVSIKSVIGSEKVEVPTPYGFEIIKIDPNIKTGDELIIKNKGIITKYESGKMIVIFEIFIPKLTSFEKKEISTILEKNADKFYEKWIKEFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
Protein: PDXH_TRIV2
Sequence: MDRTIADLRKDYTLEALSEVEVDTNPFRQFKRWFEQALAAQLPEPNAMTIATSTPDGQPSARMVLLKDFDERGFVFFTNYNSRKGQELAENPQAALVFWWAELERQVRISGRVEKVSESESDYYFYSRPANSRLGAWVSNQSEIIASREVLEQRMQEFQHKYENQEIPRPSHWGGLRVIPSQIEFWQGRSSRLHDRLLYTLLNDDSWEIHRLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RL3_PROM9
Sequence: MSIGILGKKLGMSQLFDDKGNAVPVTLIEAGPCRVTQLKTTTLDGYSAVQIGYGLSKDKHINKPEKGHLLKSGEELLKHLKEYRVEETTSYEIGNQITVKNFEVGQKVDISGKSMGRGFAGYQKRHGFSRGPMSHGSKNHRAPGSTGAGTTPGRIYPGKRMAGRYGGKQITTKGLLVLKIDDQKNLLVIKGSVPGKPGSIVNIKPNNVVGKKGGQKS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ATPA_STAAN
Sequence: MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYTGITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPYSGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIETQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQIKAMKKVAGTLRLDLASYRELESFAQFGSDLDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGGLPDAEKFDTAINEFKKSFSKSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GAL1_SALCH
Sequence: MNLKEKTRALFAEIFSYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRTVRVIAADYDNQVEEFSLDAPIVTHDSQQWSNYVRGVVKHLQQRNNAFGGVDMVISGNVPQGAGLSSSASLEVAVGTVFQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLGAKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVSLEAFNAVASELDPVVAKRVRHVLSENARTVEAASALEKGDLQRMGQLMAESHASMRDDFEITVPQIDTLVDIVKATIGDQGGVRMTGGGFGGCVVALIPEDLVPAVRQAVAQQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTSS1_MOUSE
Sequence: MEAVIEKECSALGGLFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKNKSSDTLKLQKKAKKVDAQGRGDIQPQLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDLKSLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDSGFISQDAFQSKSPSPMPPEAANQLSNGFSHCSLSSESHAGPVGAGPFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDSNGGGPTTTGGPPAGAEEAQRPRSMTVSAATRPGEEMAACEELTLALSRGLQLDVQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEAEQQEFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTVPDLPGVLPSPPDGPEERGEHSPESPSAGEGPQGVSNIPSSLWSGQAPVNPPLPGPKPSIPEEHRQAIPESEAEDQERDPPSATVSPGPIPESDPADLSPRESPQGEDMLNAIRRGVKLKKTTTNDRSAPRFS
What is the function of this protein?
Inhibits the nucleation of actin filaments in vitro.
What are the official names of this protein?
Protein MTSS 1, Metastasis suppressor protein 1, Missing in metastasis protein.
What is the protein family that this protein belongs to?
Belongs to the MTSS family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RECR_BORBR
Sequence: MDPQLPEPEPLIALIEALRRLPGVGVRSARRMAYHLLQHDLQGADMLGRALSGAVQHLRHCARCNSFTEDEVCATCANPKRDPGLLCIVETPADQNMIESSHGYRGLYYVLMGRIAPLEGVGPRELDFQRVIERACDGVVQEVILATNFTAEGETTAHFLGDALSERGLKVTRLARGVPAGSELEYVDAGTIAWALMERRST
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RISB_CLOBB
Sequence: MNIFEGKLIAEGLKVGIIVGRFNEFIGSKLLDGALDGFKRHGVNVEDIDVAWVPGAFEMPLIAKKMAKSPKYDAVICLGAVIKGSTSHYDYVCSEVSKGIANVSLETGKPVMFGVLTTNNIEQAIERAGTKAGNKGYECAVGAIEMANLIKEL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CTAA1_ACICJ
Sequence: MSGAAARGDRLVGTWLLVICFMIFGMVVGGGHARTIGAGFVIQTWQPFTGIVPPLTHAAWERAFGLYKATAQYQAMQPKMTLAQFQSLYLPMFLDRDWGRLMAVVFLVPLAVFRLRGRISNRLTAWLLFLFGLGAGEATMGWYMTYEGMTSRILQPSPLYLGPHFVLAMLIFTAMLWTALTLRNPEPAILPGLARLRGLLSVSIGLIIATIGLGALVAASGALKVYNTFPLMDGHALPPHALAMHPLWLNFLANKATVQFEHRVAATVTAIVVVIAAAMGLRAPVGAKARDLFLLLAGLVSLQYILGMSTLVSGMAELGYVHELNAVLLLAACIACRHALRGATAAVPLPVYEMKAAE
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase 1, HAS 1, Cytochrome aa3-controlling protein 1.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS11_PSECP
Sequence: MPPKTRGAVRKPRKKDKKNIALGQAHIKSTFNNTIVSITDPTGAVISWASSGEVGFKGSRKSTPFAAQMAAEAAAKRAQEHGMRKVDVFVKGPGSGRETAIRSLQAAGLEVGSIQDVTPAAHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DLTC_STRPS
Sequence: MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVEIENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCMB_AQUTE
Sequence: MDQTPIRVLLAKVGLDGHDRGVKVVARALRDAGMDVIYSGLHRTPEEVVNTAIQEDVDVLGVSLLSGVQLTVFPKIFKLLDERGAGDLIVIAGGVMPDEDAAAIRKLGVREVLLQDTPPQAIIDSIRSLVAARGAR
What is the function of this protein?
Together with HcmA, catalyzes the isomerization of 2-hydroxyisobutyryl-CoA and 3-hydroxybutyryl-CoA.  Is specific for 2-hydroxyisobutyryl-CoA and (S)-3-hydroxybutyryl-CoA, and shows only very low activity with (R)-3-hydroxybutyryl-CoA, isobutyryl-CoA and butyryl-CoA (PubMed:22433853, PubMed:25720495).  In vitro, can isomerize pivalyl-CoA and isovaleryl-CoA, with much lower efficiency (PubMed:25720495).  Plays a central role in the degradation of substrates bearing a tert-butyl moiety, such as the fuel oxygenate methyl tert-butyl ether (MTBE) and its metabolites (PubMed:22433853).
What are the official names of this protein?
2-hydroxyisobutanoyl-CoA mutase small subunit, 2-hydroxyisobutyryl-CoA mutase small subunit, HCM small subunit.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA mutase small subunit family.
Protein: TIG_HAEDU
Sequence: MSISIETLEGLQRRVTLTVNANKIEAAYKEQLKDYAKNAHVDGFRKGKVPRSIIEQRFGLAARQEVLSEEMQRTFFDAVISEKINLAGRPTFTPNNYQLGQDFSFTATFEVFPEVELKGLENIEVEKPVVEITTADIDKMIEVLRKQQATWAESDAAATANDRVIIDFVGYIDGAEFEGGKATEFTLNMGQGSMIPGFEEGIVGHKAGEQFDIDVTFPEEYHAENLKGKAAKFAITLNKVENMILPELTEEFVKKFGTAKTVEELRAEIEKNMQRELKNAVTARIKNQVINGLVTQNDIEVPVAAIAEEIEVLRRQAVQRFGGKPEMAAQLPSELFEADAKRRVQVGLLLSTVIASNEIKVDEQRVQQTIADIASAYEQPAEVIAHYAKNQRLTDNIRNVVLEEQAVEIVLEKAKVTEKTHSFDEIMAQQAQG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.