PharMolix/UniProtQA huggingface dataset:
Protein: ACPS_GLUOX
Sequence: MILGMGTDLCMISRIEKSVERFGDRFLNRVFTEAERAYADRFTGAARMGSYAKRWAAKEACAKALGTGFANGVLLQDIGVCNGPGGAPELLLSGGAEEALKRLTPSGQEAQLLVSMSDDPPFALAQVIIQSVPLAGVQSAPQASVRIEPLANAAKLR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_PSEAE
Sequence: MKALLQRVGAARVEVGGEIVGSIDRGLLVLVGVEPEDGERCAAKMLHKLLNYRVFGDDEGKMNRSLLDVQGGLLLVSQFTLAANTRSGLRPSFSSAAPPAQGEAVFEHLVKLAREAYPQVATGRFGADMQVHLVNDGPVTFLLES
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUA2A_XENTR
Sequence: MSAENGSPGLPNGGVCCATDSGRCSLVGNKVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINQNAIAFIGNGVVIHLPGLFEEAEKNLKKGQGLVGWEKRLCISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFSEFSQRFKLLAKQYKSMYPSLEIDIDGELKKLQDYADRVKPMVKDGVYYLYEALHGPPKNILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQSVGDVYGVVKAYTTRVGIGAFPTEQNNDTGEMLQTRGHEYGVTTGRKRRCGWLDLVLLRYAHMINGFTALALTKLDILDVLSEIKVGVSYKIDGKKIPHFPANQEVLNRVEVEYETLPGWNTDTCNVRTFEELPENAKKYVRYIELELGIPIKWIGVGKSRESMIQLF
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase isozyme 2 A, AMPSase 2, AMPSase 2 A, AdSS 2 A, Adenylosuccinate synthetase, acidic isozyme A, Adenylosuccinate synthetase, liver isozyme A, L-type adenylosuccinate synthetase A, IMP--aspartate ligase 2 A.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: RL22_PYRAE
Sequence: MPRHQSYSLSDEDIIELVFRNYGVKITPEQIARAYAPEQRMSWKKSVEVARFIKGMTLKQAKTWLEDVVKLKRPVPIKTFKKKQAHHATPWEGWPVAKWPVKVARRFLQVLENLENNARFRGLDVDRVVIVHAAAHKGFKIPNIMPRAFGRATRFDEQTVNVELVAVELPKEVLPKRYKLNLVKR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PPIB1_RHIO9
Sequence: MARFNLATLLVTLFLAVCTFSFVSAEGRGPVITDKIYFDIKQGDESLGRIVLGLYGKTVPKTAENFKQLATGENGYGYKGSTFHRVIKKFMIQGGDFTNHDGTGGKSIYGNRFADENFKLRHSTPGLLSMANAGRDTNGSQFFITTVVTPWLDGKHVVFGRVLEGMDVVTKIENTPTGSRSKPSVDVVIADCGLLPDEPAKEAAEHAEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase B1, PPIase B1, Cyclophilin B1, Rotamase B1.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: H16D1_CYRHA
Sequence: MNTVRVTFLLVFVVAVSLGQADKDENRMEMKDKTEQGKSYLHFAENLLLQKLEDVEAKLLEKDSEKSINSRQKRCIEEGVPCDENDPRCCSGLVCLKPTLRGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1d, U11-TRTX-Hhn1d, Hainantoxin-XVI-4, HNTX-XVI-4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: INDA1_HYPAT
Sequence: MSKEESGHVTPEKGDNVVDYQASTTVLPSEGPERDANWFTRNGLNVDSFKKKHYGPGMVELERPMKARHLHMIAIGGSIGAGFFVGSGGALAKGGPGSLFVDFLIIGIMMFNVVYALGELAIMYPVSGSFYTYSARFIDPAWGFAMGWNYVLQWAAVLPLELTVCGITISYWNSEITTAAWISLFLGVIIIINLFGALGYAEEEFWASCFKLAATVIFMIIAFVLVLGGGPKDGRYHEYWGARYWYDPGAFKNGFKGFCSVFVTAAFSFSGTELVGLAAAESTNPTKNMPGAIKQVFWRITIFYILGLFFVGLLINSDDPALLSSAAYADSKASPFVLVGKYAGLKGFDHFMNLVILASVLSIGVSGVYGGSRTLTALAQQGYAPKLFTYIDKSGRPLPSVIFLILFGFIAYVSLDATGPVVFDWLLAISGLAALFTWGSVCLAHIRFRKAWKYHGHTLDEIPFKAAGGVYGSYLGLFICVIVLMAQFYTAIAAPPGSPGVGTAEDFFKQYLAAPVVLGFWIVGWLWKRQPFLRTKNIDVDTGLREFDWDEINAERTRIAPLPAWRRIIHHTF
What are the official names of this protein?
Amino-acid permease inda1.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RECA_MYCA1
Sequence: MTQAPDREKALELAMAQIEKSYGKGSVMRLGDEMRQPISVIPTGSIALDVALGIGGLPRGRVVEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAEHALDPEYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDILVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLREKIGVMFGSPETTTGGKALKFYASVRMDVRRIETLKDGTNAVGNRTRVKIVKNKVSPPFKQAEFDILYGRGISREGSLIDMGVDQGFIRKSGSWFTYEGEQLGQGKENARTFLMENDEVANEIEKKIKEKLGIGAVVTDDLSDDGVLPAPVDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_CAMLR
Sequence: MINALKGMKDLQDDQATLYEKVVKTCEEVAKNYGFTFINCPHLELTKLFKRSVGESSDIVGKEMYEFVDKAGNDVCLRPEGTAGVVRSYIEAKMDKNQSVKRWFYHGSMFRYERPQKGRLREFHQFGVESFGVESVYEDASIILMLDEIFKRLKIHTNLKINSLGCKECMGVYKEKLIAFLNSKDGFCEDCLRRKELNPIRVLDCKNDHCQNLIKNAPKLSENLCPCCKKDYEKLQKILSENGIEFECDEKLVRGLDYYSKSAFEFISDEIGAKAAVAGGGRYDRLIEYLDGKSGYGVGFAMGIERIMAILEQKQDIKKRNGIYLCAMDEAYIDTIFKLANTLRKKHKVYLSYEAKKLAKHLNQADNANAKIFLCIGEDEMQKEEIFYKNLDTKENKNIKIANLENEL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB2_I69A0
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPMTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDIDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEELLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSVAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMIGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDEGTSGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: METK1_ARATH
Sequence: METFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRAIGFVSDDVGLDADKCKVLVNIEQQSPDIAQGVHGHFTKCPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYYNDKGAMVPIRVHTVLISTQHDETVTNDEIARDLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVANGMARRALVQVSYAIGVPEPLSVFVDTYETGLIPDKEILKIVKESFDFRPGMMTINLDLKRGGNGRFLKTAAYGHFGRDDPDFTWEVVKPLKWDKPQA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MASTP_PROSY
Sequence: INWKALLDAAKKVL
What is the function of this protein?
Potent antimicrobial peptide against both Gram-positive and Gram-negative bacteria (By similarity).  This hemolytic peptide shows potent histamine releasing activities on rat peritoneal mast cells.
What are the official names of this protein?
Mastoparan, Protonectarina-MP.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Mastoparan subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TLX3_MOUSE
Sequence: MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
What are the official names of this protein?
T-cell leukemia homeobox protein 3, Homeobox TLX-3, Homeobox protein Hox-11L2, Respiratory neuron homeobox protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPMI_SYMTH
Sequence: MSAYRRPVALIVLDGWGLNPDPRANAVAMARHPNFDRLMARYPHTTLTASGEAVGLLPGQMGDSNVGHLNLGAGRIVYQTLVRIWRSIQDGSFYTLPVWRPVLDRAKQPGKALHLMGLVSDGGVHSHIDHLLALIDLAKRENVERVYVHAFLDGRDVPPQSALPYLERVEAKLKETGIGAIATISGRYYAMDRDKRWDRTEKAFLAITQGIGHTAGSVAEAVERAYARGETDEFVQPTVIEGVDGRVREGDGVIFFNFRPDRARQLVRALHETAFDGFKRPEGYRPVELVTMTQYDQTFTDIPVAFGPQFVDVPMGQVVAEAGLRQLRIAETEKYAHVTYFFNGGEERVFPGEERVLVPSPKVATYDLKPEMSAYEVAREAVKWIEEDRTDFIVLNFANPDMVGHTGVLEAAIRAVEAVDECLGQVVDALLAKGGAAVIIADHGNCDQMVDYETGAPHTNHTLNPVPCILVDDQRLDAKLKPGVLANVAPTLLEIIGLPKPPQMDADSLLVSNAEGA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: MURR_ECOLC
Sequence: MLYLTKIRNAESEFTENEQKIADFLRANVSELQSVSSRQMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNAMALHLHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIQRSSELTQRLK
What is the function of this protein?
Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc).  Binds to two adjacent inverted repeats within the operator region.  MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator.
What are the official names of this protein?
HTH-type transcriptional regulator MurR, MurPQ operon repressor.
Protein: CMOB_PASMU
Sequence: MIDFRPFYQHIATTHLSAWLETLPLQLKQWEKQTHGDYAKWAKIVDFLPHLDADHIDLKSAVKSESVSPLSAGEQQRLVYHLKQLMPWRKGPYHLHGIHIDCEWRSDFKWDRVLPHLAPLKDRTILDVGCGSGYHMWRMVGEGAKIVVGIDPTELFLCQFEAVRKLLNNDRRANLIPLGIEQMQPLAAFDTVFSMGVLYHRKSPLDHLSQLKNQLVRGGELVLETLVVDGDINTVLVPADRYAKMKNVYFIPSVPALINWLEKVGFKNVRCVDVAPTSLAEQRKTDWLENESLIDFLDPCDHTKTIEGYQAPTRAVILANK
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: LPTD_YERPS
Sequence: MKKRFPTLLATLIWTALYSQHTLADLAEQCMLGVPTYDQPLVTGDPNQLPVRINADKTEANYPDNALFTGNVIVQQGNSTLTANQVELTQVQKPGEVIPLRTVTATGDVNYDDPQIKLKGPKGWSNLNTKDTDIDKGKYQMVGRQGRGDADLMKLRDQSRYTILKNGTFTSCLPGDNSWSVVGSEVIHDREEQVVEVWNARFKIGKVPVFYSPYMQLPVGDKRRSGFLIPNAKFTSNNGFEFLLPYYWNIAPNFDATITPHYMERRGLQWQNEFRYLLAPGSGTMALDWLPNDRIYTGPDGTDKNATRWLYYWGHSGVMDQVWRFNINYTRVSDPAYFTDLTSQYGSTTDGYATQIFTAGYANENWNATLSSKQFQVFTAAGNSNAYRAQPQLDMNYYKNDVGPFDMHVYGQAAKFTSVNPTNPEASRFHIEPTVNLPLSNSWGSINTEAKLLATHYQQDIPASFADNASNPKLKDSVNRVLPQFKVDGKVVFDRSMDWATGFTQTLEPRAQYLYVPYRNQDDIYIYDTTLMQSDYSGLFRDRTYSGLDRIASANQVSTGLTSRIYDDARVERFNVSVGQIYYFSRSRTGNTEAIDNSNDTGSLVWAGDTFWRINDQLGLKGGAQYDTRLGSLTLGNAIMEYRRDADRMIQLNYRYASPKYIQAAVPKVYNPDYQQGISQVGTTASWPIADRWAIVGAYYYDTKAKQPASQLVGLQYNTCCWAVNLGYERKITGWNAQGQTSKYDNKIGFNIELRGLSGGHSLGTAQMLNSGILPYQSAF
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS14_PROM4
Sequence: MAKKSMIARDVKRKKLVERYATKRKKLLDEFNSAKDPMERLEIHRKIQALPRNSAPSRMRNRCWATGKPRGVYRDFGLCRNQLRERAHKGELPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: LGT_BLOFL
Sequence: MQFFYTPNFNPIILKVGCISFYWYGMMYVLSFIFAMWFLKYRKRYIVNDIFSSTSEIENLLYLNFLGVVIGGRIGYVLFYQWSMLSQDKLWFFKLWEGGMSFHGGLIGVIISIMWFSYCKNQSFLKISDFIVPAVPVGLGLGRLGNFINGELWGRVTFDIPWAMLFKNALLQDLLTLKIHPEWKFFFDYYGALPRHPSQLYEMILEGIVLFVVIYIFSCKSRPEGSISGLFLLLYGLFRIIIEFFRQPDIHIGLINNFITLGQVLSFPMVIFGFIIMYVSYKFK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSH_TRIV2
Sequence: MSSFEYPQDLRYLDTHEYVRLDGEIATIGITEFAVDQLGDVVFLELPDIGDLLTKGDTFGTIESVKAVEDLNAPITGTVVERNEILIESPDAVADDPYGEGWFLKVRVNDPDEVNDALTADEYRAEVEGE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: FIS_SERMA
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: CH10_PSYCK
Sequence: MNIRPLHDRIVVRRIEEETKTAGGILLPGSAQEKPSQGEVLATGNGQIRDNGETRALDVKAGDKVLFGQYAGQTVKVDGEELLIMKESDVLGVLEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_DESVH
Sequence: MTTRSTDQTEHLRALGQKTPYPAAGPSTDLLEAFPNRFPDRPYIVSIAFPEFTSLCPVTGQPDFATIVVEYIPDQFCVESKSFKVYMFAFRDHQSFMETITNTILDDMTTKLQPLWCRVKGLFTPRGGTQLHVFAERFKEVEPARAQALRDMVSEWKRENNRHGA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_PSE14
Sequence: MTLILGIDPGSRITGYGVVRDTGRGCVYVASGCIRTGSGELHERLQIVYRGVREVIKTYGPVTMGIEKVFMARNADSALKLGQARGAAIVAGAEEALEIAEYTATQVKQAVAGTGGANKEQVMMMVMHLLKLTQKPQIDASDALAIALCHAHTRSSLIPHGLSTARSRGGRLRL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: GTR7_RAT
Sequence: MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTVTEVFVIVGVFLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAVNYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPPVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEKEETIDAGPPTASPAKETSF
What is the function of this protein?
Probable sugar transporter.  Even if its physiological substrate is subject to discussion, it is able to transport glucose and fructose.  Does not transport galactose, 2-deoxy-d-glucose and xylose.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 7, Glucose transporter type 7, GLUT-7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Protein: SYK_NOSP7
Sequence: MSEEDIRAARLEKVEQLKQLGTNPYAYRWESTHHAAQLQEQFADLASGEEVDLEVAIAGRIMARRVFGKLAFFTLQDETGTIQLYLDKNRIQESMADIDADAFNHLKQLTDAGDILGVKGTIKRTEKGELSVYVKQYTILTKSLLPLPDKWHGLTDVAKRYRQRYVDLIVNPEVRQTFRRRAQITAGIRRYLEQRDFLEIETPVLQSEAGGADARPFITHHNTLEMELYLRIATELHLKRLIVGGFEKVFELGRIFRNEGISTRHNPEFTTIEVYQAYADYNDMMALTEGIITTVAQEVLGTLQITYQGEPIDLTPPWRRVTMHDLVKEFTGLDFNSFQTLEEAKTASKNAGIPGVDEAKSIGKLLNLAFEEKVEANLIQPTFVIDYPVEISPLAKPHRSQPGLVERFELFIVGRETGNSFSELTDPIDQRERLEAQAERKAAGDLEAQGVDEDFLTALEYGMPPTGGLGIGIDRLVMLLTDSASIRDVIAFPLLKPEGSVIKQFSYEQKTQTLTIEFDSGSVYEYFKVPPSVKEDLDNAPSKGQHFNKFIKGKFKFEQLS
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXS_CHLAD
Sequence: MEKSTWTTKVGLAQMLKGGVIMDVVTPEQARIAEEAGAVAVMALERVPADIRAQGGVARMSDPELILAIKQAVTIPVMAKARIGHFVEAQVLEAIGVDYIDESEVLTPADEEHHINKHKFRVPFVCGCRNLGEALRRIAEGAAMLRTKGEAGTGNVVEAVRHARAVYSEIRRLQSMNEDELFTYAKQIQAPYELVKQVATEGKLPVVNFAAGGIATPADAALLMQLGVDGIFVGSGIFKSGNPIKRARAIVEATTHYNDPEIIAEVSKGLGEAMVGINIDQIPAEQLMARRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: PYRG_BACVZ
Sequence: MTKYIFVTGGVVSSLGKGIVAASLGRLLKNRGMSVTIQKFDPYINVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNRFSNVTTGKIYSAVLKKERRGDYLGGTVQVIPHITNELKDRVYRAGKETNADVVITEIGGTVGDIESLPFLEAIRQMKSDIGHENVMYIHCTLVPYIKAAGELKTKPTQHSVKELRSLGIQPNIIVVRTEMPISQDMKDKIALFCDIDTKAVIECEDADNLYSIPLNLQEQGLDKLVCDHMKLECKDPDMTEWKDLVTKVKNLSKTITISLVGKYVELQDAYISVVESLRHAGYAFDADVKIKWINAEEVTESNIQELTGGTDGIIVPGGFGDRGVEGKIIAAKYARENKIPFFGICLGMQIASIEYARNVLGLEGAHSAEIDPSTPYPIIDLLPEQKDVEDLGGTLRLGLYPCKLQEDTKAFEAYADEVVYERHRHRYEFNNEYRQQMEENGFVFSGTSPDGRLVEIIELKDHPWYVACQFHPEFKSRPTRPQPLFKDFIGASVQAAEQK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.