PharMolix/UniProtQA huggingface dataset:
Protein: FIEF_PECAS
Sequence: MNPHYARLVTLAAVSATAVALVLFVMKVFAWWHTGSVSLLASLVDSLVDIAASLVNLLVVRYSLQPADTEHAFGHGKAESLAALAQSMFISGSALFLILTGLQHSLEPQTLHAPEVGMWVTLIALVATLLLVSFQRWVVKHTHSQAVRADMLHYQSDLLMNGAILVALALSWKGITRADSLFALGIGVYILYSALRMGYDAVQSLLDRALPDEEHRAIAEVIVNWPGIRGAHALRTRRSGPTRFIQLHLEMDDALPLAEAHQIADDLEQALRKQFPGADIIIHQDPVSAVPENQRGRLTA
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CRBL_VESMA
Sequence: FLPIIGKLLSGLL
What is the function of this protein?
Mast cell degranulating peptide.  Induces the chemotaxis of neutrophils.
What are the official names of this protein?
Vespid chemotactic peptide M, VESCP-M, Ves-CP-M.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Crabrolin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRG_MYCBT
Sequence: MRKHPQTATKHLFVSGGVASSLGKGLTASSLGQLLTARGLHVTMQKLDPYLNVDPGTMNPFQHGEVFVTEDGAETDLDVGHYERFLDRNLPGSANVTTGQVYSTVIAKERRGEYLGDTVQVIPHITDEIKRRILAMAQPDADGNRPDVVITEIGGTVGDIESQPFLEAARQVRHYLGREDVFFLHVSLVPYLAPSGELKTKPTQHSVAALRSIGITPDALILRCDRDVPEALKNKIALMCDVDIDGVISTPDAPSIYDIPKVLHREELDAFVVRRLNLPFRDVDWTEWDDLLRRVHEPHETVRIALVGKYVELSDAYLSVAEALRAGGFKHRAKVEICWVASDGCETTSGAAAALGDVHGVLIPGGFGIRGIEGKIGAIAYARARGLPVLGLCLGLQCIVIEAARSVGLTNANSAEFDPDTPDPVIATMPDQEEIVAGEADLGGTMRLGSYPAVLEPDSVVAQAYQTTQVSERHRHRYEVNNAYRDKIAESGLRFSGTSPDGHLVEFVEYPPDRHPFVVGTQAHPELKSRPTRPHPLFVAFVGAAIDYKAGELLPVEIPEIPEHTPNGSSHRDGVGQPLPEPASRG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ACPH_KLEP7
Sequence: MNFLAHLHLAHLADSSLPGNLMADFVRGNPQGDYPAEIIDGIYMHRRIDVMTDNLAEVKEAREWFRPQTRRVAPITLDVMWDHFLSQHWAQLSPDLPLDEFVRYAERQIVPILPDSPPRFVNLNQYLWSERWLERYREMDFIQRVLNGMASRRPRLEALRDSWQDLDTHYDRLETQFWRFYPQMMRLAENKQL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: DNAA_ECOSM
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVAQTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFSA_SALTY
Sequence: MSPTIELLCGHRSIRHFTDEPVTDAQREAIIAAARSTSSSSFLQCSSIIRITDRALREALVPLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLLLGVVDTAMMGQNALTAAESLGLGGVYIGGIRNNIESVTELLKLPKHVLPLFGLCLGWPADNPDLKPRLPAELVVHENQYQPLDEKLLARYDEQLAEYYLTRGSNTRRDTWSDHIRRTLIKENRPFILEYLHKQGWATR
What is the function of this protein?
Catalyzes the reduction of nitroaromatic compounds using NADPH.  Has a broad electron acceptor specificity.  Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product.
What are the official names of this protein?
Oxygen-insensitive NADPH nitroreductase.
What is the protein family that this protein belongs to?
Belongs to the flavin oxidoreductase frp family.
Protein: VU25_HHV6Z
Sequence: MGLSSSKDIDLLVNFIENRQGATLALPWPEDYRLTLHSVENIPDISREDVQNWAKTYMCCEGELVVVGVIHKAKTRTCRGPIVLQGARGHIYVYNGFFDRSLYHVASSFHDLFSNGLRFFYPIYETCDYALDSTVALDMIAHSKSFSELLHYRNERKNAFFTLKTYPYKTFVRFCNLSMTGFSSKHLIQWRRKLQTSLLDVVFIVQHNFFGDWRELVVVFDGHGMLFCVDREESLLFIARNMSDFLKIGCLRYNENRRLHTQWFTQDTDYIKQVDEMFSRDVLCPLREHCQRSRRDRGLLKICTSLVRGINCIERG
What are the official names of this protein?
Protein U25.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: RR16_TOBAC
Sequence: MVKLRLKRCGRKQRAVYRIVAIDVRSRREGKDLRKVGFYDPIKNQTYLNVPAILYFLEKGAQPTGTVQDILKKAEVFKELRPNQS
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL7_FRATW
Sequence: MAITKEDILNAVAEMSVMDVCDLVKMMEDKFGVSAAAAVAVAAGPVAGPAEAAEEKTEFDVVLVDAGSNKIAAIKAVRGATGLGLKEAKDAVEGTPFTVKEAASKEEAEALKKQLEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TM45B_HUMAN
Sequence: MANFKGHALPGSFFLIIGLCWSVKYPLKYFSHTRKNSPLHYYQRLEIVEAAIRTLFSVTGILAEQFVPDGPHLHLYHENHWIKLMNWQHSTMYLFFAVSGIVDMLTYLVSHVPLGVDRLVMAVAVFMEGFLFYYHVHNRPPLDQHIHSLLLYALFGGCVSISLEVIFRDHIVLELFRTSLIILQGTWFWQIGFVLFPPFGTPEWDQKDDANLMFITMCFCWHYLAALSIVAVNYSLVYCLLTRMKRHGRGEIIGIQKLNSDDTYQTALLSGSDEE
What is the function of this protein?
Plays a role in innate immunity (PubMed:35938871).  Mechanistically, promotes alphaviruses RNA degradation by interacting with the viral polymerase nsP4 and the mRNA-capping enzyme nsP1 and thereby interfering with the interaction between viral RNA and nsP1. (PubMed:35938871).
What are the official names of this protein?
Transmembrane protein 45B.
What is the protein family that this protein belongs to?
Belongs to the TMEM45 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AROA_YERPY
Sequence: MLESLTLQPIALVNGTVNLPGSKSVSNRALLLAALAEGTTQLNNVLDSDDIRHMLNALQALGVNFRLSADRTCCEVDGLGGKLVAEQPLSLFLGNAGTAMRPLAAVLCLGNSDIVLTGEPRMKERPIGHLVDALRQGGAQIDYLEQENYPPLRLRGGFRGGELTVDGRVSSQFLTALLMTAPLAEQDTTIRIMGDLVSKPYIDITLHLMKAFGIDVGHENYQIFHIKGGQTYRSPGTYLVEGDASSASYFLAAAAIKGGTVRVTGIGKKSVQGDTKFADVLEKMGAKVTWGDDYIECSRGELQGIDMDMNHIPDAAMTIATTALFATGPTTIRNIYNWRVKETDRLTAMATELRKVGAEVEEGEDYIRVVPPVQLTAADIGTYDDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQFARLSQLA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_ACIBC
Sequence: MQIFYDKDCDLSIIQSKKVAIIGYGSQGHAHALNLKDSGVDVTVGLRAGSASWKKAENAGLKVAEVPAAVKQADLVMILTPDEFQSQLYRDVIEPNIKEGATLAFAHGFSVLYNQVVPRKDLDVIMVAPKAPGHTVRSEFQRGSGVPDLIAIHQDASGNARNVALSYASGVGGGRTGIIETSFREETETDLFGEQAVLCGGAVELVKMGFETLVEAGYAPEMAYFECLHELKLIVDLMFEGGIADMNYSVSNNAEYGEYVTGPEVINEQSREAMRNALKRIQSGEYAKMFIQEGALNYPSMTARRRQNAAHGIEQTGAKLRAMMPWIQANKIVDKEKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RECX_STRPB
Sequence: MKITKIEKKKRLYLIELDNDESLYVTEDTIVRFMLSKDKVLDNDQLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIPDIITQLQEEQWIDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQKLFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIENLLDKELDKQYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPSE_CHICK
Sequence: MLVLLLLVLLLAVPPRRTAELQLGLREPIGAVSPAFLSLTLDASLARDPRFVALLRHPKLHTLASGLSPGFLRFGGTSTDFLIFNPNKDSTWEEKVLSEFQAKDVCEAWPSFAVVPKLLLTQWPLQEKLLLAEHSWKKHKNTTITRSTLDILHTFASSSGFRLVFGLNALLRRAGLQWDSSNAKQLLGYCAQRSYNISWELGNEPNSFRKKSGICIDGFQLGRDFVHLRQLLSQHPLYRHAELYGLDVGQPRKHTQHLLRSFMKSGGKAIDSVTWHHYYVNGRSATREDFLSPEVLDSFATAIHDVLGIVEATVPGKKVWLGETGSAYGGGAPQLSNTYVAGFMWLDKLGLAARRGIDVVMRQVSFGAGSYHLVDAGFKPLPDYWLSLLYKRLVGTRVLQASVEQADARRPRVYLHCTNPRHPKYREGDVTLFALNLSNVTQSLQLPKQLWSKSVDQYLLLPHGKDSILSREVQLNGRLLQMVDDETLPALHEMALAPGSTLGLPAFSYGFYVIRNAKAIACI
What is the function of this protein?
Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans.  Participates in extracellular matrix (ECM) degradation and remodeling.  Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group.  Can also cleave the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying a 2-O-sulfo group, but not linkages between a glucuronic acid unit and a 2-O-sulfated iduronic acid moiety (By similarity).  Increases cell adhesion to the extracellular matrix (ECM), independent of its enzymatic activity.
What are the official names of this protein?
Heparanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 79 family.
Protein: HSLU_SHEPC
Sequence: MSEMTPREIVHELDAHIIGQKKAKRSVAVALRNRWRRMQLDVDFRQEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVEQIIRDLTDIAIKLTREQQMGKCRQLAEEHAEERILDALLPKPKNDWESTDTDTGSNTRQIFRKKLREGQLDDKEIDIDVAQPQIGIEIMSPPGMEEMTNQLQSLFKNMGQAPAKRRKMKIKEAFKLLIEEEAAKLVNQEDLKEQAIEMVEQHGIVFLDEIDKICKRGETSGPDVSREGVQRDLLPLVEGCTVTTKHGMVKTDHILFIASGAFQMAKPSDLIPELQGRLPIRVELDALSADDFKRILTEPHASLTEQYVALMGTEGVKVEFTESGIESIAKAAWQVNERTENIGARRLHTVMEKLMEDISYEASDKSGSAFVIDADYVSAHLDNLVQDEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPY_HUMAN
Sequence: MLGNKRLGLSGLTLALSLLVCLGALAEAYPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRYGKRSSPETLISDLLMRESTENVPRTRLEDPAMW
What is the function of this protein?
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
What are the official names of this protein?
Pro-neuropeptide Y.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle.
Protein: GLPK_DESRM
Sequence: MMAKKYVLALDQGTTSCRAILFDRDSNIVGVAQKEFTQIYPKPGWVEHNAEEIWSTQYGVIAEVVAKTGIKPEEIASIGITNQRETTVVWNKNTGKPVYNAIVWQCRRTTEICDELKVKGLEETFKKKTGLVVDAYFSGTKVKWILDNVPGTREMAEKGELLFGTMDTWLIWKLTGGQVHVTDYSNASRTLMYNIRELCWDEELLGYLNVPMSLLPTVKASSEVYGYTQPDQFLGHSVPIAGVAGDQQAALFGQACYEPGMAKNTYGTGCFMLMNTGDEVYESKNGLLTTIAWGLDGKVTYALEGSIFIAGAAIQWLRDGLKILESAPDSEYFASKVDGTDGVYLVPAFAGLGAPYWDMRARGAIVGLTRGTTKEHIIRAALDSLAYQTKDVLGAMEADSNIKLQALKVDGGAVANNLLMQFQADILGVPVERPQVIETTALGAAYLAGLAVGFWESKEELAKRWKLDYQFESVMAEDQRNKLYNGWEKAVGRSMDWATEE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: NS1_MUMIP
Sequence: MAGNAYSDEVLGATNWLKEKSNQEVFSFVFKNENVQLNGKDIGWNSYKKELQEDELKSLQRGAETTWDQSEDMEWETTVDEMTKKQVFIFDSLVKKCLFEVLNTKNIFPGDVNWFVQHEWGKDQGWHCHVLIGGKDFSQAQGKWWRRQLNVYWSRWLVTACNVQLTPAERIKLREIAEDNEWVTLLTYKHKQTKKDYTKCVLFGNMIAYYFLTKKKISTSPPRDGGYFLSSDSGWKTNFLKEGERHLVSKLYTDDMRPETVETTVTTAQETKRGRIQTKKEVSIKTTLKELVHKRVTSPEDWMMMQPDSYIEMMAQPGGENLLKNTLEICTLTLARTKTAFDLILEKAETSKLTNFSLPDTRTCRIFAFHGWNYVKVCHAICCVLNRQGGKRNTVLFHGPASTGKSIIAQAIAQAVGNVGCYNAANVNFPFNDCTNKNLIWVEEAGNFGQQVNQFKAICSGQTIRIDQKGKGSKQIEPTPVIMTTNENITVVRIGCEERPEHTQPIRDRMLNIHLTHTLPGDFGLVDKNEWPMICAWLVKNGYQSTMASYCAKWGKVPDWSENWAEPKVPTPINLLGSARSPFTTPKSTPLSQNYALTPLASDLEDLALEPWSTPNTPVAGTAETQNTGEAGSKACQDGQLSPTWSEIEEDLRACFGAEPLKKDFSEPLNLD
What is the function of this protein?
Multifunctional protein which displays endonuclease and helicase activities required for initiating and directing viral DNA replication (PubMed:12050365).  Also plays a role in viral packaging and transactivation of several promoters (PubMed:7636987).  Binds site-specifically to 2-3 approximate tandem copies of the tetranucleotide 5'TGGT3' within the origins of replication (Ori), unwinds this hairpin region and nicks one DNA strand thereby initiating the rolling circle replication (RCR) (PubMed:17898054, PubMed:12050365, PubMed:9349487).  Cooperatively binds Ori with host PIF and probably other host factors, which activate the nickase function of NS1 (PubMed:11435581, PubMed:12050365).  Becomes covalently attached to the 5' end of the nick and provides a 3'OH for priming DNA synthesis (PubMed:12050365).  The helicase activity unwinds DNA in a 3'-5' direction on the longer strand (PubMed:12050365).  Participates in the transcriptional regulation of several promoters including the viral p38 promoter that regulates the expression of VP1 and VP2 transcripts (PubMed:7636987, PubMed:8551622).  Inhibits the host cell cycle during the G1/S transition, the S-phase, and the G2/M transition (PubMed:9188601, PubMed:11602746).  These arrests may provide essential cellular factors for viral DNA replication.  Promotes apoptosis in host cell (PubMed:21295324).
What are the official names of this protein?
Initiator protein NS1, NS1, NCVP1, Non-capsid protein NS-1, Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the parvoviruses initiator protein NS1 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: MNMC_ENT38
Sequence: MKQNVVQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLEGNHLNARFPLHPRSQFVVAESGFGTGLNFLTLWQAFDQFRADHPEATLQRLHFISFEKYPLIGHDLKLAHQHWPELAQWAEQLQAQWPLPLGGCHRLLLDEGRVTLDLWFGDINELTDQLDDSLNQKVDAWFLDGFAPAKNPDMWSEHLFAAMARLARPGATLATFTCAGFVRRGLQDAGFTMQKCKGFGRKREMLTGVMAQDNALPARAPWFARSGLENRETAIIGGGIASALLAFALLQRGWRVTLYCADKSPANGASGNRQGALYPLLSAHDPAISQFFPAAFTFARRLYDALPVTYAHDWCGVTQLGWDEKSQQKIDQMLSLGLPEQIAAAVDAQQILDNTGLPTDCGGIRYPEGGWLCPAELTAAVINLAQSRGLAVHYGYHLDSLNHQQGDWQLRFNNGADAQHSSVVLANGHRISDFSQTEKLPVYPVGGQVSHIPTTPQLEKLRQVLCYDGYLTPQNPENGHHCIGASYHRGQTEMHYSEADQQQNRQRLVDCFPKAEWAKEVDVSDSDARCGVRCATRDHLPMVGNVPDYESTLTEYQNLAENTETAVTAPVYPGLFMLGALGSRGLCTAPLLAEILASQMSEEPIPMDSTTLAGLSPNRLWVRKLLKGKAVK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALR_HAEIN
Sequence: MSTIRDVAKLANVSVATVSRVLNHSLSVSENTRLVVEQAIAQLAYQPNANAQALAVQNTDTIGVVVTDVTDAFFAILVKAVDKVAEAHQKTILIGIGYHHAEKEREAINTLLRKRCSSLVVHSKALSDDELSHYLNTVQGMVIINRVIKGYEHRCVSLDNQKGTYLATEMLIRYGHQHIAYIGSNHAIFDEVERRNGYLAALKDHNYPIIEQAITLNSPDFEGGEKAMIDLLSYNKNLTAVVAYNDSMAAGAISVLNENNISVPSQFSIIGFDDMPIARYLIPKLTTIRYPIDLMATYAAKLALSLTDEKIITPPVVQFNPTLVRRFSVESR
What is the function of this protein?
Repressor of the galactose operon.  Binds galactose as an inducer.
What are the official names of this protein?
HTH-type transcriptional regulator GalR, Galactose operon repressor.
Protein: RPOC_RICFE
Sequence: MSVVNFYGQLSNTQQFDQIRINIASPDQVRSWSFGEVTKPETINYRTFKPEKDGLFCARIFGPVKDYECLCGKYKRMKNRGITCEKCGVEVTVSRVRRERMGHIELAAPVAHIWFLKSLPSRISTLLDMTMRDVEKILYFENYVVVDPGLSILQKGELLTEEELQKAKDKYGEDAFTASIGAEVIQQMLKEIDFLKLKQELYEELQTTSSEVKKKKLVKRLKLVEDFLESENKPEWMIMDVLPVIPPEIRPLVMLDGGRFATSDLNELYRRVINRNNRLKKLIESKAPDIIVRNEKRMLQEAVDALFDNGRRGRAAKNANKRPFKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGSELKLHQCGLPKKMALELFKPFIYSKLELYGIATTIKAAKRMVEAEKPEVWDVLEEVIREHPVLLNRAPTLHRLGIQAFEPLLIEGKAIQLYPLVCAAFNADFDGDQMAVHIPLSIEAQLEARVFMMSTNNILSPANGRPIIVPDKDIVLGLYYLTLAFDNEVGEGMMFSDLAEMEHALYNKFITIHTKIKYRRNQLNAEGKMVPVIIDTTYGRLMVGELLPSNPNIEFKFINKQLTKKDISLVIDLVYRHCGQKATVIFADQLMKLGFKYACSSGISFGMDDMVVPESKSTHINETQLEIKEFEQQYSNGLITYGEKYNKVVDAWSRCTDRVANDMMKEIATPPVSDDPNHQKINAIYMMAISGARGSFQQIKQLGGMRGLMTKSNGQIIQTPIISNFKEGLTEFECFNSANGMRKGQIDTALKTASSGYLTRKLVDVAQDCIITEKDCGTDKGIEVKSVIEGGEVIVPLAEKILGRTAAIDIFHPVTNDLILNKGELINEAKLEQIESAGLDRIMIKSVLTCESTTGICSICYGRDLATGTLVSEGEAIGVIAAQSIGEPGTQLTMRTFHIGGAATKGAEVSSVEASYDAKVKIISRNVVINSEERKIVMSRNCELLLLDNNGNEKARHKIPYGARLLVDDGDMVIKTQKLAEWDPYTIPIITEKSGKVLFKDMVEGISIRDVTDEATGIPSKVIIESKQYSRGAELRPRIQLLDAKGEVIALSNGLEARYYLPVGAVLSVEDGVQISVGDIIARIPKESTTTKDITGGLPRVAELVEARRPKDHAVIAEIDGRVEFGKDYKSKRRIIIHPIDETMSIEYMVPKGKHVVVNEGDFVKKGDLLIDGNPVLQDILKVMGVEVLANYIVKEVQAVYRLQGVKIDDKHIEVIIRQMLQKVEITDSGGTTLLAGEKIDRHEFEEINEKAIKNGLKPAEAQLILQGITKASLQTRSFISAASFQETTRVLTEAAIAGKIDKLRGLKENVIVGRLVPAGTGYFMDKMRKAAVKLDEENV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: CCD1_LOTGI
Sequence: MAARSALCFLAIITLFVYACGRPALNFNSIYKDSRSSVKHFPRVTDSRYAYTKIDSKLDSILSELQKEQNDRDDDDDDDDEDDLFDEINDIFDDVMDDDIEEDGDDIHEVEKIEEAVDDVIDMIDDIIDDDADDDSDDVPEDLNDAQEDILELIKDSNDDKNDDETSDIIDDILDIVEDAKDADDHRPIADIRVVESLSKPGAVAEDDKESKKIDETVQELLDEIKDVVEDANDDVNDILDTDDEDEDEDVQEEKDEDIHEDVGNVMVNLMHGVHGVTGGGVNHDIYEEIEEKMDEVDDFIDDAIDEHNDDDVNDDENDDVYDEHDDLVDDVNDDADDDNDDADDDNDDADDDNDDSDDNDDSDDDNDDDDIDDVADDVLEVIVDAVEAMNTPTNV
What are the official names of this protein?
Coiled-coil domain-containing protein 1, Aspartate-rich protein.
What are the subcellular locations of this protein?
Secreted.
Protein: PSPB_ECOL6
Sequence: MSALFLAIPLTIFVLFVLPIWLWLHYSNRSGRSELSQSEQQRLAQLADEAKRMRERIQALESILDAEHPNWRDR
What is the function of this protein?
The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions.  PspB is involved in transcription regulation (By similarity).
What are the official names of this protein?
Phage shock protein B.
What is the protein family that this protein belongs to?
Belongs to the PspB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CCA_PICTO
Sequence: MIDYKKILGDYTPDYEESLRLKCIENGIIKKLNDIISSRNIDAEPVSVGSYSKGTNLKNSDLDIFIVFSKKYPKNEMESIGLSLGHYILENGVEKYAEHPYVSGYIENVKIDIVPAYKIEPGQRIVSTVDRTPLHTKYVIENTDENLRNDIRLLKIFMKANNVYGSEVSKAGFSGYLCEILVINFKSFDAVIKYFSKLKGRLIIPENSGKKFQEPVVIVDPVDPTRNAGAAVSLENLSRMKIASKLFLLNKNESFFYPREISPRYHKRGTCIYIITLKRPDIIDDIIYPQVFRFERQIFNIADRYGFMPVSSEINVDNNIEILIELQRDVLPDVSKHAGPPVDSDESINFINVWKDRALRGPYIERDRLYVDSETRIKSFYDALNLELKKMDIGKNLNKLKDGIKIIKYNNSDFNVVKKFFSKDIFH
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
Protein: SECY_MYCGA
Sequence: MAKTNSKNLLGQKIIKLLRNRDFVISVFVTLFLILLFRVISVIPLPGITISQNKNNLNNGVSDFFDLFNLLGGGGLSQLSLFAVGISPYISAQIIMQLLSTDLIPPLSKLAKSGELGRRRIELITRFVTLPFAVVQAFAIIALINNQRNGAIRFENGGILHQAFYIVTMTAGTYIGIFIGDIISKKGVGNGITLLILSGILARLPDGFIVMYRVLGGVIISTNPILTSAINFSLYFLAFLVLLLAISFVNSSTRRIPIQQTGEGMVLGNEKLPYLPIKLNAAGVIPVIFASSIMSIPITIAEFQPQSEARWFVEDYLSLRTPVGISLYVILIIIFTFFYSYIQINPEQLAENFNKSHKFIPGVRPGLDTEKHITKVLMRINFIGAPFLAIVAVIPYIISLVLNVPTTLSLGGTGIIIMVSASMELYRSLRSAATTTSYQRLRKDIANRIEAELSLNDYMNKPNLEHDQYGLLGQHKKVEPTQDKKKNPSDPLEVSQLW
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: E3145_ADEB3
Sequence: MEPDGVHAEQQFILNQISCANTALQRQREELASLVMLHACKRGLFCPVKTYKLSLNASASEHSLHFEKSPSRFTLVNTHAGASVRVALHHQGASGSIRCSCSHAECLPVLLKTLCAFNFLD
What is the function of this protein?
Protects virus-infected cells from TNF-induced cytolysis.
What are the official names of this protein?
Early E3 14.5 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3_15 family.