PharMolix/UniProtQA huggingface dataset:
Protein: SYFB_HALMA
Sequence: MPVVDVDPDELRYLTGHSEKDDDELKSDLFNLGLEFEGWTEDDEFQLEFAPDRLDRLSVEGVARSLRYHYGDDRGVEIPNTNSADWTIEVEDQPDERPYVTGAIVRGLDMDEAALESLIQLQEKLHATMGRKRAKGAIGVHDLTMLKGDSVTDETGKSITYTSADPDEATFVPLDADAEMTPSEVMASHETGQTYGDLVADFDRVPAIYDAIGLFSFPPVINGRRTEVSVDSRDLFIEMTGTNQWTIDHMCNIVCYALAARGGQVEKVDVSYADDAPGEYAGKTLERPDFSVRTKTVTHDRIESILGVSLDSREVVDYAERAGLDATETESDDGVAYDVEVPPYRVDVIHPLDIIDDIGRALGFNSLEPTYPDVSTVGGRHERSRLEDAARDALVGLGFEDLLNFHMTNEVENFERMNLSTPEAEDGNDADTVGLADPVTIQEPYSEDYTILRTWALPSIMMVLENNTHRSYPQDLAEIGLAAGLDDSENTGVAEHRTVAAALARTDASYEDAKARLQALADAFDKDLETPPTTHPSFIGGRAAEVVLDGESVGVIGEIHPKVLVEHDLELPVAAFEFRLDALA
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPPR_SHIFL
Sequence: MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSFHRYTRPEMDMAIRKARDAGRHISYFGPEANDFGLLEQTFIEYGQSGKGKSRKYLHTYDEAVPWNQVPGTFTPWQPLPEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLEWIQKLIRDTSERGHSREAVMDSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFAAKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIMLPLVQRLMEGKKIE
What are the official names of this protein?
Probable phosphoribulokinase, PRK, PRKase, Phosphopentokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoribulokinase family.
Protein: Y2165_ALKCK
Sequence: MSKEKLDRINELSKLAKTVGLTKKQAMEQKALRNEYLSAFRSSFTDHLHTVKVVDAKGNDVTPQKLKDSKAQKHKRLH
What are the official names of this protein?
UPF0291 protein ABC2165.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_CALMQ
Sequence: MSKKPEGKVEAKPTAKATEAAAAAAPAAAGAEEESSAEAGRRGWIMPTPIPQEEWKNFKYRGFTFDELMKMPMNEFIKLLPARQRRTLKRGLRPCHRQLLEKIRKAKAFAAKGKSIPVRTHCRDMIILPEMVGLTIFVYNGITYIPVPISPWHIGHYLGEFAITTKIVQHGEPGLKATKSTLHIAAK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SSPH2_GEOKA
Sequence: MELLRAKRMAEAGEIVPVMYKGKQVVIQHVDDEREMARVYFTDEPEHEQDVPVRLLEEQ
What are the official names of this protein?
Small, acid-soluble spore protein H 2, SASP H 2.
What is the protein family that this protein belongs to?
Belongs to the SspH family.
What are the subcellular locations of this protein?
Spore core.
Protein: RECO_NITMU
Sequence: MNVDKQRQEAQPAFVLHSYPYLETSLIVEVFTQNSGRIAVVAKGAKRPTSPLRGLLRAFQPLLLSWGGKSELRTLHKAEWQGGQLPLQGTALICGFYLNELLIRLLHRNDPHERLFACYQEALSDLSTASDYIPILRRFEQRLLQEMGYALTLDHDVSSGKPIKPTQMYCYEIERGPIASSNGSCPFNLELSGKTLLDMYQGDYLAPLTRLQSRILMRHLLSHYLGDKPLHTRQLLKEFQQL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RGN_PIG
Sequence: MSSIKIECVLRENCHCGESPVWGEASNSLLFVDIPAKKVCRWNALSKQVQRVTLDAPVSSVALRQAGGYVATVGTKFCALNWEDESAVVLAAVDKDKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGSLYALFADHHVEKYFDQVDISNGLDWSLDHKIFYYIDSLSYSVDAFDYDLQTGKISNRRSIYKMEKEEHIPDGMCIDTEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCFGGKDYSEMYVTCARDGLDPQGLLQQPEAGGIFKITGLGVKGLPPYPYAG
What is the function of this protein?
Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone.  Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis.  Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro).  Calcium-binding protein.  Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity).
What are the official names of this protein?
Regucalcin, RC, Gluconolactonase, GNL, Senescence marker protein 30, SMP-30.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX2_HUMAN
Sequence: MAAEREPPPLGDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAEDISANSNGPKPTEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA
What is the function of this protein?
Involved in several stages of intracellular trafficking.  Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:16179610).  Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex (PubMed:17101778).  The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling.  The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable).  Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:23085988).  Required for retrograde endosome-to-TGN transport of TGN38 (PubMed:20138391).  Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901).
What are the official names of this protein?
Sorting nexin-2, Transformation-related gene 9 protein, TRG-9.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Note=Colocalized with SORT1 to tubular endosomal membrane structures called endosome-to-TGN transport carriers (ETCs) which are budding from early endosome vacuoles just before maturing into late endosome vacuoles (PubMed:18088323). Colocalized with F-actin at the leading edge of lamellipodia in cells in a KALRN-dependent manner (PubMed:20604901).
Protein: NPIIF_ARTBC
Sequence: MKFFTALAAVGALLAPAVALPTPASEASHNQTLSVRLVRAGHTMVRAIVTNNGERPLHLLSFNTIMDENPTSKVDVSHEDGGEVEFLGMLPRYDLSDLTEDLFTRLAPKDSVEHLFDIATVHDLKWDGKYTLTARGAIPVAEDGGTDIIDHVYYESNALEMDIDARKAAMVPRAFDDYFSKGLDKRRPLDICNPMKEKALRAALQDAQKVATEAAAAAQNNTEKVFEFFRARDPGTRKEVSKRLASISGVATMDGGSVTWFCSDGPRRCSPRIIAYTFPARNEVHPCSLFWQLPHRTNECHRQDRIGTVIHEGAHNPNAVTPHCKDHGYGYNRATALSHQRAMGNADNYALFANARQLVFCLLHLFLALPFIYIFANF
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine.  May be involved in virulence (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog ARB_04336, Deuterolysin ARB_04336.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_MESH7
Sequence: MKKVSRNLLQARQMVDKNRFYSLEEAMELVKKTSYTKFSGSVDLAIRLNLDTRKADQQLRGAVVLPHGTGKSVRVLVATDSSEVAAKSLEAGADLIYSTAELEQNLKIDNFNFDVIVVEPKLMPILGRYGKKLGPKGLMPNPKTGTVSPNPEKAVAEIKKGKANYRADRYGIIHSLIGKTNMEVPQLVENANTLLRLIKRLKPNTVKGNYFKNLTVSASMGPSIKIRFDNL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TRM61_ASPOR
Sequence: MHSPFLTPGSRSQLDNLALLQLRRDQTIPTILQLHDEKNGGYKEGKVTNTRFGSFPHITLCDQPWGSQIIASKVDTGSRGRTQKMKRKADELDSSTQAEDKPSPQTPVAASSGFLHLLYPTPELWTASLPHRTQVVYTPDYSYILHRLRARPGSTVIEAGAGSGSFTHASVRAVFNGYPSDDQPTKKRRLGKVCSFEFHAQRAEKVRVEVNQHGLDGLVEVTHRDVYEDGFLLGDPKTGKSPKANAIFLDLPAPWLALKHLVRNPPEGTESPLDPTSPVYICTFSPCLEQVQRTISTLRQLGWLGISMVEVNNRRIEVKRERVGLDLGNIRGTVVFPKSVDEAVERTRALEERAQLFRATQNQSDGDSTPAPKAENEAKGGQQESEVPVYKQGRVMTRSELDLKNHTSYLVFAILPREWTEEDEKRCREKWPSNRVQEPQGPQKSKKQLKRESREKRDLQRKEQSQPETESQKE
What is the function of this protein?
Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit trm61, tRNA(m1A58)-methyltransferase subunit trm61, tRNA(m1A58)MTase subunit trm61.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TOLB_BURA4
Sequence: MRLMTKLGFRALVASCLIAAGGAANAQVNVLITGVGSTQFPIATANFANEAGLPQQVTSIVRADLARSGKFTNIDAGSTPVPETASVDLGAWKAKGANAFVAGSVNREANGQYKVNFILYDTVKQQSLGGLSLTATDTTLRTAGHKIADYIYQKLLGVRGVFATRLSYVIKTGNRYQLQISDSDGQNARIALSSTEPIISPAWSPSGTKVAYVSFERKKPIVYIHDLPTGRRYMVSDQKGNNSAPAWSPDSNTLAVALSLTGNTQIYTVNANGGGLRRLTQSSSIDTEPYYSPDGRWIYFTSDRGGAPQIYRMPAQGESAGAAQRVTFTGSYNTSPRISPDGKLLAYISRTGGGFKLYVQDLQTGAANAITNTNRDESPSFAANGQYLLYATQSGGRNVLAAVPSDGSAPPQILSVQGGSVREPSWGPFMQ
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MYB61_ARATH
Sequence: MGRHSCCYKQKLRKGLWSPEEDEKLLTHITNHGHGCWSSVPKLAGLQRCGKSCRLRWINYLRPDLKRGAFSPEEENLIVELHAVLGNRWSQIASRLPGRTDNEIKNLWNSSIKKKLKQRGIDPNTHKPISEVESFSDKDKPTTSNNKRSGNDHKSPSSSSATNQDFFLERPSDLSDYFGFQKLNFNSNLGLSVTTDSSLCSMIPPQFSPGNMVGSVLQTPVCVKPSISLPPDNNSSSPISGGDHVKLAAPNWEFQTNNNNTSNFFDNGGFSWSIPNSSTSSSQVKPNHNFEEIKWSEYLNTPFFIGSTVQSQTSQPIYIKSETDYLANVSNMTDPWSQNENLGTTETSDVFSKDLQRMAVSFGQSL
What is the function of this protein?
Transcription factor that coordinates a small network of downstream target genes required for several aspects of plant growth and development, such as xylem formation and xylem cell differentiation, and lateral root formation (PubMed:22708996).  Regulates a specific set of target genes by binding DNA to the AC cis-element 5'-ACCTAC-3' (PubMed:23741471).  Functions as a transcriptional regulator of stomatal closure.  Plays a role the regulation of stomatal pore size independently of abscisic acid (ABA) (PubMed:16005292).  Required for seed coat mucilage deposition during the development of the seed coat epidermis (PubMed:19401413).  Involved in the induction of trichome initiation and branching by positively regulating GL1 and GL2.  Required for gibberellin (GA) biosynthesis and degradation by positively affecting the expression of the enzymes that convert GA9 into the bioactive GA4, as well as the enzymes involved in the degradation of GA4 (PubMed:28207974).
What are the official names of this protein?
Transcription factor MYB61, Myb-related protein 61, AtMYB61.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL17_ALIB4
Sequence: MRHKHGYRKLSRTSSHRKALLKNLAIAIIEREKIETTVPKAKELKRYIERLVTVARNADFNTHRQVFAALQSKEATKKLINEIAPKYEGRNGGYTSIVKTRIRKGDATPMAFISFI
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: KAX31_ANDMA
Sequence: GVEINVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCTPK
What is the function of this protein?
Potent inhibitor voltage-gated potassium channels Kv1. 3/KCNA3 (Kd=0. 65 nM) and Kv1. 1/KCNA1 (Kd=41 nM) (PubMed:7517498).  It appears to block channel activity by a simple bimolecular inhibition process.  Induces a transient period of fast flickering in the channel openings, followed by an almost complete blockade of the channel.  Its binding affinity to rat brain synaptosomes is 5-fold higher than this of KTX-3.  Binding of the toxin to the channel is associated with significant structural rearrangements in both molecules.  It also shows a weak interaction with nicotinic acetylcholine receptors (nAChR), suggesting it may weakly inhibit it (PubMed:31276191).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 3.1, Kaliotoxin, KTX, Kaliotoxin-1, KTX-1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TLPB_FLAPS
Sequence: MEKVKSSYLPYTIRILISFLFIISAIAKMYPSPYFAISTFEVKQLYPLGFSEIIAPWFSRILIGIELALGILILQNNFLRKLIIPITILLLAVFVGHLSYVTFLSGGNTGNCGCFGELIPMTPIQAIIKNIIAIFLLVYLFFLLSKTNDKNNFYVVIGITLATIISLFLLAPIKKNTNDFTISPIENTLIDSTKNEIIAPILKDSVITTVKVDSVKKAIPTKIEEVISTTEPTKHKSGYAKLFPKIDTGRKTLCFFVPGCDHCRKAAKELTELKQKNANFPEILIIFMNEEVDLIPDFFKETGAEYPYKIIEIIPFWNALGTGKDTPGVKYIWNGNTYKYYNGITDNKFNPIDYQALINKPFSELKK
What are the official names of this protein?
Protein TlpB.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL34_LISMO
Sequence: MKRTYQPSKRKRKKVHGFRTRMSTKNGRRVLASRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: U2AF1_DROME
Sequence: MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRIHNKPTFSQTVLLQNLYVNPQNSAKSADGSHLVANVSDEEMQEHYDNFFEDVFVECEDKYGEIEEMNVCDNLGDHLVGNVYIKFRNEADAEKAANDLNNRWFGGRPVYSELSPVTDFREACCRQYEMGECTRSGFCNFMHLKPISRELRRYLYSRRRRARSRSRSPGRRRGSRSRSRSPGRRGGGRGDGVGGGNYLNNERDNMRGNDRGNDRDRRKGGGGGGGGGGGRY
What is the function of this protein?
Necessary for the splicing of pre-mRNA.  Binds to the polypyrimidine tract of introns early during spliceosome assembly (By similarity).
What are the official names of this protein?
Splicing factor U2af 38 kDa subunit, U2 auxiliary factor 38 kDa subunit, U2 snRNP auxiliary factor small subunit.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNB_AERHH
Sequence: MFQDNPLLAQLKQQIRENIPKKEGVIRASDRGFGFLEVDEKTSYFVPPPYMKKVMHGDRVSALIRTEKEKEVAEPDALLEQSVTRFVARVKMFRDRLNVVADHPLIKDAIKARVKKGLDEKEFKEGDWVVATLKRHALVDGNFSAEITQTIASQEDHNVPWWVVLARHNLAQVEPADLPEWKVIEEEELPRTDLTATPFFTIDGAKTKDMDDALAIRKLDNGWELLVAIADPTAYVAEGSELDKEAAQRAFTVYMPGRNVPMIPRTLSDELCSLKEGEERNTLCARLLIAEDGLLLEETEFFAARISSHARLTYDDVSDWAEHGKQLDIDAGVLAQLPLMKAMTEARIAWRTEHALVFPDRPDYDFELGENGEVLAIHVEPRRIANRMVEESMIAANICAGRVLGKQVGYGIFNVHTGFDEESLDGAIDLLKSAEAPFEKEEIASLSGFCALRRWIDNLDTRWLDGKIRRFQSYALMSAEPGAHYGLGLDAYATWTSPIRKYGDMVNHRLLKAVIAGKTPGERPSLELTEHLTACRRLHRMVERDIGDWLYVRYLKADAGTDKVFNAEIIDVMRAGLKLRLRENGAVVFMPARHILDNKDRLECNWDNGRVYLDKTEVVYELGQIIEVKLTEAVEETRSLIAKPAVELVPGPAPVAPTSEADATPADEAPKAE
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEI2_CAEEL
Sequence: MSGLDDRKKLTHAKNRKPLNDIPKSAENRPNTRSTSSRRGAEKDVPITFIGSSRTVKADLPEFTNTRSRRPLHSESKKELSRNPVSRGEEHSSSLPKSSPESSVSVMSSNASLWSACTEEVNKIGVCAKRESRNLRVYKMKSFTSNMEQILSNDNQLAPTVIRILNSRNSWCLNSCHACLTFIMENITSDNYGKRSACLKALASITNSLLDTIIGFASTKTRRIGVDVVAEERAAKATECIHNFRKIVKNRDKIYKQIDQETIYKLDAILERLKKVSSHK
What is the function of this protein?
Forms a heterodimeric complex in conjunction with mei-1 which severs microtubules in vitro in an ATP-dependent manner.  This activity may promote rapid reorganization of cellular microtubule arrays.  May act to target mei-1 within the cell.  Required specifically for meiotic spindle formation in the female germline.
What are the official names of this protein?
Meiotic spindle formation protein 2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle pole. Note=Localized to the spindle poles and condensed chromatin during female meiosis. Also localized to the polar body. Correct localization requires mei-1.
Protein: RIBB_PSEAE
Sequence: MALNTIDELIEDIRQGKMVILMDDEDRENEGDLIMAAECVRTEDINFMVKHARGLVCMPMTRERCERLGLPLMVQRNGSGFGTKFTVSIEAAEGVTTGISAADRARTVQAAAAKNAVAADIVSPGHIFPLMAQPGGTLARAGHTEAACDLARMAGFEPSGVICEVMNDDGSMARRPELEAFAAEHGIKIGTIADLIHYRLIHERTVERIAEQPLDSELGHFNLITYRDSVEGDVHLALTLGKVCAEEPTLVRVHNMDPLRDLLQVNQPGRWSLRAAMTKVAEAGSGVVLLLGHQIGGDDLLAHVREIASAPAPAPKATTTYSTVGAGSQILRDLGVRKMRLLSAPMRFNAISGFDLEVVEYLPAE
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: RLMN_PARDP
Sequence: MNAAPITQDLLTIPRKLPETAGRNLVGLTREQLHEALIQAGTPERQARMRVGQIWQWIYHWGVRDFAQMTNLAKDYRALLAENFEIALPEIVTRQISADGTRKYLLRISGGHEVETVYIPEENRGTLCISSQVGCTLTCSFCHTGTQKLVRNLTAGEIVGQVMVARDDLGEWPKPGAPKDETRLVSNVVLMGMGEPLYNFDNVRDAMKVVMDGEGISLSRRRITLSTSGIVPEIAKTAEEIGCLLAVSFHATTDETRDKLVPVNRKWNIETLLNALREYPRLSNSERITFEYVMLDGVNDSDEDARRLVRLIRGIPAKVNLIPFNEWPGSPYRRSGWERIEAFADIVHKAGYASPIRTPRGEDIMAACGQLKSATERGRKTAAQIAAEARA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_MYCUA
Sequence: MPYIDLNADLGEGFGIWQLGDDDAMLGIVTSANVACGFHAGEPAGLLRVCRAAAERGVRIGAQVGYRDLAGFGRRFIDVDPEDLVAEVVYQIGALQAIAQSCGSTVSYVKPHGALYNTIVTHRDQAAAVAEAVRMVDATLPVLGMTGSVFFQQATDLGLRTVAEAFADRAYRSDGQLVSRREHGAVLADAAAIAQRAVSMVASGKVTAVDGTQVPITMESICVHGDSPGAMQIATAVRDRLTAAGNEIRAFC
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: RL2_XANAC
Sequence: MPLMKFKPTSPGRRSAVRVVTPDLHKGAPHAALLDSQSKSGGRNHHGRITVRHVGGGHKQHYRIIDFKRNKEGIPARVERIEYDPNRTAHIALLCYVDGERRYIIAPKGLKAGDQVIAGANAPIKTGNTLPLRNIPVGTTVHGIELKPGKGAQIARAAGAAVQLVAREGIYATLRLRSGEMRKVPVECRATIGEVGNDEHNLEKLGKAGAKRWRGVRPTVRGAAMNPVDHPHGGGEAKAGQGNPHPVTPWGVPTKGYKTRKNKRTQQFIVRDRRG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: UEV1D_ARATH
Sequence: MTLGSGGSSVVVPRNFRLLEELERGEKGIGDGTVSYGMDDGDDIYMRSWTGTIIGPHNTVHEGRIYQLKLFCDKDYPEKPPTVRFHSRVNMACVNHETGVVDPKKFGLLANWQREYTMEDILVQLKKEMSTSHNRKLVQPPEGTCF
What is the function of this protein?
Has no ubiquitin ligase activity on its own.  The heterodimer with UBC catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'.  This type of poly-ubiquitination does not lead to protein degradation by the proteasome.  Mediates transcriptional activation of target genes.  May play a role in the control of progress through the cell cycle and differentiation.  Involved in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 variant 1D, Ubc enzyme variant 1D, Protein MMS ZWEI HOMOLOG 4.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: JAZF1_MOUSE
Sequence: MTGIAAASFFSNTCRFGGCGLHFPTLADLIEHIEDNHIDTDPRVLEKQELQQPTYVALSYINRFMTDAARREQESLKKKIQPKLSLTLSSSVSRGNVSTPPRHSSGSLTPPVTPPITPSSSFRSSTPTGSEYDEEEVDYEESDSDESWTTESAISSEAILSSMCMNGGEEKPFACPVPGCKKRYKNVNGIKYHAKNGHRTQIRVRKPFKCRCGKSYKTAQGLRHHTINFHPPVSAEMIRKMQQ
What is the function of this protein?
Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2 (By similarity).  Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity (PubMed:24380856).  Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD (PubMed:24930994).  Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue (PubMed:24380856, PubMed:25614086).  Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity (PubMed:25614086, PubMed:24380856).
What are the official names of this protein?
Juxtaposed with another zinc finger protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: DABA2_NITHX
Sequence: MVMVDALNLGRRLRVRSTAYVAGEPVPFSWPMRTFISRNPLYGLEHMPFEQAVRRGAELFHARMFLPRSDYQRWQREGKVRQDTLAEEIARRAQALPAVPGIDWPRWLQALMQSAHDRDVVVPGVRAPDVHAALHGQPPSAQAVDVAVLLPALEQRLHGLTLPEAVDALWGTRLADELDELVIKSYLDFFDEDQSSWRMPGRERGLFAAWSEIAQRNARMFLRRLHVRRTLGRVQDPESAVVHVMEEMGIDPDAWSAYFTRELTRLYGWTGFVRWRSSAKHYYWAQRYPAEVVDLLAVRLVVGLALLQESARHRRTPVRREQLDALLHERGAECLLRNALHSGEVLPDWAQRIDDTLSRGGSKRCEALLQRYWPLWQARQGQDQAAALRELAAAADATAALEVLSPEDIAGLIQGLQEFARQEGMVWTLAMEAQAIDQLLAQVQVPQDLAAGKRPFAQAWFCIDVRAEPIRRHLERVGDYQTFGIAGFFGVPVGFLGYGKGSESHFCPAVVTPKNLVLELPAELDPEEDDLLSTLGHVLHDLKSSVLSPYVTVEAVGMLFGLDLFGKTLAPLGYSRWRNRIDADKPVTRLLVDKLTREQADSIIRTLQRAMIVKALHAELHIERERVDDDMIRELRETALRHREGPTRLQRTFGVSDKQEAEFIDKLREVYRVDADYASYQLVRLGRIGYSLDEQVNYVHTALTMIGLTKTFSRFVLIVGHSGQTENNPYESALDCGACGGASGLVNARVLAQMANKTAVRERLRGMGIDIPDDTWFLPALHNTTTDAIELSDLVLLPPRHLVYLDRLRNGLRAASRLAAAERMPKLLPQARAIEPAQAWRLAHRLAVDWAQVRPEWGLSKNVYGIIGRRSLSERADLQGRPFLMSYDWRCDPKGRLLENLLAAPVVVGQWINLEYFFSTVDNARLGSGSKAYHNVAGRFGVMTGSLSDLRTGLPAQTVMREGQPYHEPMRMIALIEAPLDFAGRALQSVVKVKSLVLGGWIRAIVIDPTQGYKPFVFNNGQWEERPPLVAPAEEEHAA
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA 2.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.