PharMolix/UniProtQA huggingface dataset:
Protein: MNMG_STRPB
Sequence: MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDMLAFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQADKSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTALRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTEIQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGLEKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGINAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMRLTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTDAMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMKRMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEGNGKAHRKY
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_DESDA
Sequence: MTVFADILDTVRRHEPVVHCITNYVTVNDCANMVLAAGGSPIMADDAAEVEDIVALSQALVINIGTLNSRTVESMLVAGRRANSMGKPVVLDPVGAGASALRNSTLQRLLGEVRFAAIKGNASEIGFLAGKDAKARGVDAQDSCLVTEDRLESAAATARHLSESTGAVVVVSGAIDIVAYSGGAWAVRNGHPLMARITGSGCMSAAVMGCCLGVAPYEMPQACLCAVSALGVAGEIAAETMVGGGGEMGGLGGGTGSYRALLLDAMSLLDGLALGSRADVTRIQM
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: DJC27_HUMAN
Sequence: MEANMPKRKEPGRSLRIKVISMGNAEVGKSCIIKRYCEKRFVSKYLATIGIDYGVTKVHVRDREIKVNIFDMAGHPFFYEVRNEFYKDTQGVILVYDVGQKDSFDALDAWLAEMKQELGPHGNMENIIFVVCANKIDCTKHRCVDESEGRLWAESKGFLYFETSAQTGEGINEMFQTFYISIVDLCENGGKRPTTNSSASFTKEQADAIRRIRNSKDSWDMLGVKPGASRDEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTALLKNIK
What is the function of this protein?
GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed.  May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
What are the official names of this protein?
DnaJ homolog subfamily C member 27, Rab and DnaJ domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIE_THIDA
Sequence: MRTFPGGVYALTRETPDTERLLAEVEAALAGGVAAVQYRDKSGDVAQRHAQASELAALCRRFGVPLIVNDDLRLADLAGADGVHLGRDDASIREARIILGPAKFVGASCYQSLDLARAAQTAGADYVAFGSFYPSPTKPAAARADVALLARASRHIALPVVAIGGITAANAAPLIDAGADSLAVLSALFDAPDVRRAAAELNRLFAAEPEE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RL19_CLOBK
Sequence: MLEVIKAIEAEQVRSDLPEFNVGDTVKVHQKIKEGTRERVQVFEGTVLKRQNGGARETFTVRRVAYNVAVEKTFPVNSPLIEKIQVVRKGKVRRAKLYYLRDRVGKAAKVKERI
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ATPB_DROVI
Sequence: MFALRAAAKADKNLLPFLGQLSRSHAAKAAKAAAVANGKIVAVIGAVVDVQFDDNLPPILNALEVDNRSPRLVLEVAQHLGENTVRTIAMDGTEGLVRGQKVLDTGSPIRIPVGAETLGRIMNVIGEPIDERGPIPSAKTSPIHAEAPEFVDMSVEQEILVTGIKVVDLLAPYCKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGFSVFAGVGERTREGNDLYNEMI
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Protein: Y4198_BACCZ
Sequence: MNGIRDVVKEEQPRERLLLEGAGSLSNRELLAVLLRTGSKEESVLKLSDKILHHFDGLRMLKDATLEELVSIHGVGVAKASQLIAAFELGRRMVRLEYQNRYSIRNPEDCARYMMEEMRFLQQEHFVCLYLNTKNQVIHRQTIFIGSLNSSIVHPREVFKEAFRRAAASIICLHNHPSGDPAPSREDIEVTKRLVECGRIIGIEVLDHIIIGDHKFVSLKEKGHI
What are the official names of this protein?
UPF0758 protein BCE33L4198.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RS5_METVA
Sequence: MAEKRAEKRKFNTDSWEPKTQVGRMVKEGTISDISYIMDKGLPLLEPEIVDVLLPDLEEQVLDVKLVQRMHKSGRRARYRATVVVGNKNGYVGVGMGKSKEVGPAIRKAIAQAKLSLIKVRVGCGSWECGCGSPHSIPFTAKGTCGSVKVELLPAPRGVGLVAGNVAKAVLGLAGVKDAWTTTYGDTRTTYNFAEATFDALNNLNFVRCLPEQKAKLGLTEGRVL
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CA13_CONSE
Sequence: MFTVFLLVVLATTVVSSPSDRASDGRNAAANEKASDVIALALKGCCSNPVCHLEHSNMCGRRR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like Sm1.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MDTC_YERPE
Sequence: MKFFALFIQRPVATTLLTLAITLSGIIGFSLLPVSPLPQVDYPVIMVSASMPGADPETMASSVATPLERALGRIAGVNEMTSTSSLGSTRIILQFDLNRDINGAARDVQAALNAAQSLLPSGMPSRPTYRKMNPSDAPIMIMTLTSDTFSQGQLYDYASTKLAQKIAQTEGVSDVTVGGSSLPAVRVELNPSALFNQGVSLDAVRQAISAANVRRPQGSVDAAETHWQVQANDEIKTAEGYRPLIVHYNNGSPVRLQDVANVIDSVQDVRNAGMSAGQPAVLLVISREPGANIIATVDRIRAELPALRASIPASIQLNIAQDRSPTIRASLDEVERSLVIAVALVILVVFIFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGVKPKVAALRGVREVGFTVLSMSISLVAVFIPLLLMAGLPGRLFREFAVTLSVAIGISLVISLTLTPMMCAWLLRSHPKGQQQRIRGFGKVLLAIQQGYGRSLNWALSHTRWVMVVLLSTIALNVWLYISIPKTFFPEQDTGRMMGFIQADQSISFQSMQQKLKDFMQIVGADPAVDSVTGFTGGSRTNSGSMFISLKPLSERQETAQQVITRLRGKLAKEPGANLFLSSVQDIRVGGRHSNAAYQFTLLADDLAALREWEPKVRAALAKLPQLADVNSDQQDKGAEMALTYDRETMARLGIDVSEANALLNNAFGQRQISTIYQPLNQYKVVMEVAPEYTQDVSSLDKMFVINSNGQSIPLSYFAKWQPANAPLAVNHQGLSAASTISFNLPDGGSLSEATAAVERAMTELGVPSTVRGAFAGTAQVFQETLKSQLWLIMAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNISAREAIFQASLLRFRPIIMTTLAALFGALPLVLSSGDGAELRQPLGITIVGGLVVSQLLTLYTTPVIYLYFDRLRNRFSKQPLMKLE
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y980_PASMU
Sequence: MAGHSKWANIKHRKAAQDAQRGKIFTKLIRELVTAAKLGGGDVNANPRLRTAVDKALSSNMTRDTINRAIERGVGGGDDTNMETKIYEGYGPGGTAVMVECLSDNANRTISQVRPSFTKCGGNLGTEGSVGYLFSKKGLILITSGDEDVIMEAAIEAGADDVQVQEDGSFEVYTAWEELGAVRDGIESAGIKIDNAEVTMIPSTTVELDAETAPKLLKLIDMLEDCDDVQNVYHNGEISDEIAAML
What are the official names of this protein?
Probable transcriptional regulatory protein PM0980.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP4_SPIOL
Sequence: TSAEVPATAQGVTHALEGTQ
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element.  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit delta', mitochondrial, F-ATPase delta' subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: CCR3_MACFA
Sequence: MTTSLDTVETFGPTSYDDDMGLLCEKADVGALIAQFVPPLYSLVFMVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLFTLPFWIHYVRERNWVFSHGMCKVLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVVTSIVTWGLAVLAALPEFIFYGTEELFPETLCSAIYPQDTVYSWRHFHTLRMTILCLALPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILISTYQSILFGPDCERSKHLDLFVLVTEVIAYSHCWVNPVIYAFVGERFRKYLRHFFHRHVLMHPGKYIPFLPSEKLERTSSVSPSTAEPELSIVF
What is the function of this protein?
Receptor for C-C type chemokine.  Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15.  Subsequently transduces a signal by increasing the intracellular calcium ions level.  In addition acts as a possible functional receptor for NARS1.
What are the official names of this protein?
C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIHI_SALA4
Sequence: MKKPTSAPRSKAFGKQRRKTREELNQEARDRKRLKKHRGHAPGSRAAGGNSASGGGNQNQQKDPRIGSKTPVPLGVTEKVTQQHKPKSEKPMLSPQAELDLLETDERLDALLERLEAGETLSAEDQAWVDAKLDRIDELMQKLGLSYDDDEEDDEEDEKQEDMMRLLRGGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: TSNAX_RAT
Sequence: MNGKEGPGGFRKRKHDNFPHNQRREGKDASSSSPVMLAFKSFQQELDTRHDKYERLVKLSRDITVESKRTIFLLHRITSAPDMEEILTESESKLDGVRQKMLQVAQELSGEDMHQFHRAVTTGLQEYVEAVSFQHFIRTRSLISMEEINRQLTFTTDDSGKESKAPPADGQDKQLVTWRLKITPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYTLKQSLSKVENACYALKVRGSEIPKHMLADVFSVKTEMIDQEESIS
What is the function of this protein?
Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC).  Possible role in spermatogenesis (By similarity).
What are the official names of this protein?
Translin-associated protein X, Translin-associated factor X.
What is the protein family that this protein belongs to?
Belongs to the translin family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Golgi apparatus. Nucleus. Note=Expressed in the cytoplasm in the presence of TSN. Accumulate in the Golgi complex of mid-late pachytene spermatocytes (By similarity).
Protein: RL16_SHEB5
Sequence: MLQPKRMKFRKMFKGRNRGLANGTEVSFGTFGLKAVGRGRLTARQIESARRAMTRHIKRQGQIWIRVFPDKPITSKPLEVRMGKGKGNVEYWVCQIQPGKVLYEMNGVSEVIAREAFALAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PGPH_BACSU
Sequence: MLKKKAKTKSSSKKWSSFKNARSMHVLLYLLLAAIMFALLFVHVKPETLDLDLFSVSDKTIYAPATVEDQKATEEKKQAAEDAVEDQYTLKKEYTDNRIDLVSSIFDSISEVKKSSEEGSKSPSEKSMVKSVKDKLTSDVNDSISEDSIKTLLKADSEDFSFVRDTVITAVNTVMSSEIPSDKLSDAKDKVEKELKSNSIPSKYLGAATEIGRFAIIPNYVFDPKATEAKRQEASDNVQQVQIKQGQVLVEENDLIDREVYRKLELTGLLNNSNLFKPISGLLIMIGLFIATLVYYFEKQKQNLKFKNQSILLFSIITTLLLVIMEVVSLFQKMEYNNIGYLVPIAAGAILIKLLMNERIAILGSIILAICGSMMFNQGVTGTFNYVIGIYYLISGISGVLFLGKHNARSKILQTGLFVAFINMVVVLSLLLIQNTALSGLEIGTLMLMGVVSGFASSVLIIGLMPFFETGFGILSTMRLLELSNPNHPLLRKILTETPGTYHHSVMVANLSEAACEAVGANGLLARVGAYYHDLGKTKRPQYFIENQMNIDNPHDKLSPQLSKNIIISHTTDGANMLRSYKFPKELVDIAEQHHGTSLLKFFYYKAKEKGDQITEEEFRYPGPKPQSKEAAIISVADSVEAAVRSMHNPNPERIEKLVRGIISDKLQDGQFSECDLTFKELDTIAKTLCATLKGIFHSRIEYPEATKKVK
What is the function of this protein?
Probably has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); may be the major c-di-AMP PDE in the cell (PubMed:26240071).  In B. subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess (PubMed:26240071).
What are the official names of this protein?
Cyclic-di-AMP phosphodiesterase PgpH, c-di-AMP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the PgpH phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GIMA4_MOUSE
Sequence: MEVQCGGAGFIPESSRSSHELGNQDQGIPQLRIVLLGKTGAGKSSTGNSILGEKVFNSGICAKSITKVCEKRVSTWDGKELVVVDTPGIFDTEVPDADTQREITRYVALTSPGPHALLLVVPLGRYTVEEHKATQKILDMFGKQARRFMILLLTRKDDLEDTDIHEYLEKAPKFFQEVMHEFQNRYCLFNNRASGAEKEEQKMQLLTLVQSMVRENGGRCFTNKMYESAECVIQKETLRMQELYREELEREKARIRREYEEQIKDLRDELEREIRRARMEREFKEREAIFTKNQQNARKEVENTSMILELIIKAWEIASFIFNQFMKD
What is the function of this protein?
During thymocyte development, may play a role in the regulation of apoptosis.
What are the official names of this protein?
GTPase IMAP family member 4, Immunity-associated nucleotide 1 protein, IAN-1, Immunity-associated protein 4.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ASI4A_DANRE
Sequence: MPIEFVCKIKFAEEDEKQKGNQDGDKESLIEESCSPPTKDLAGFASASSLHGINHIFVSGRLGVRQTLWALAFLVSLALFLYQAAKCAISYLEHPHVTALNEEATPEMVFPAVTICNINRFRFSALTDADIYHLANLTGLPPKNKDGHKPTDLEYPAPDMQDIFNRTGHQLEEMLKSCNFSGQNCSAEDFTVVYTRYGKCYTFNGNKTTSRKTKQGGMGNGLEIMLDIQQDDYLPIWKETNETSLEAGIRVQIHSQDEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRSTSEQMIPGYDTYSISACRLRCETLEVLRECKCRMVHMPGDANICTPSDIKCVDKALALLQKSSGDTCFCETPCNLTRYGKELSMVKIPSKGSARYLSRKYDKSEDYIRDNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASVLTILEILDYVYEVIKHRLERLLRPQRDDKKQTQQQQQASTVATVNLEEMKAKDSSEMSRSHSEGAYANTILPNHHHHHRTHHRVSEDFAC
What is the function of this protein?
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride.
What are the official names of this protein?
Acid-sensing ion channel 4-A, ASIC4-A, Acid-sensing ion channel 4.1, Amiloride-sensitive cation channel 4-A, ZASIC4.1.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTVP_RHOJU
Sequence: KEGYPTNSEGCKITXLFNDPYCKGXCINLSTQAD
What is the function of this protein?
Does not cause symptoms of intoxication, paralysis or death in insects (A. domestica).
What are the official names of this protein?
Non-toxic venom protein.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDHN_SYNP6
Sequence: MALITTGSKFLRALEQEGALAVYAPLEGGYEGRYLRRLRSKGYSALTYSARGLGDPAQFLMDIHGVRPPHLGKQTIGNEAAVGRVEYVLPLVGYPLQNLPANAKGLVLWLLEGHVLSPQELSYFVTLPQAEPRLKVVIEMGGDRGFSWQPLAAVAEAA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit N, NAD(P)H dehydrogenase I subunit N, NDH-1 subunit N, NDH-N.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhN subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DNAJ_PSYA2
Sequence: MSKRDFYEILGVSKTADNKEVKRAYRKLAMKYHPDRNSDDPDAEDKFKEASMAYEVLSSEEKRSAYDRMGHAAFENGMGGGGGGGNFQDIFGDIFGNFGDIFGQSRGGGGGRSRRGSDLRYVIELTLEEAVRGCKKEISFTAPAPCDTCDGKGAKNASDIVTCQTCHGQGQVRMQQGFFAVQQACPHCGGTGKQIKNPCSDCHGNGVKDKSRTLEVSIPAGVDDGDRVRLSGEGEAGGAGVQNGDLYVEVRVKPHNVFTRQGADLYMDVPISITDAALGKEVEIPTLDGKVKIKVAEGTQSGKLLRVRGRGVTPVRTTMKGDLICRVVIETPVNLTREQKDLLRQFQDTLDGDSKHQQSPHKKSFFKKIGDLFD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DC2I2_MOUSE
Sequence: MAMCASPRPFRRVGSAGAAALAAGGAGGAERRGRPAPLQDETLGVASVPSQWRSVQGIRGETKSCQTAGIATAESSAQARTHADAQVQTEAPEEPAAMAPVSQYDTLRLEAFLRRVEAMVIRELNNNWQSHAFDGYEVNWTEQQQTVSCLHTLVYPLAQGQGLHVTGISWNSTGSVLACAYGRLDDGDWSTLKSYVCTWNLDRQGLNPQQPSVVVEVPSAVMCLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSAATDGKVLLWRGSGAGQLRLTKGFALAVQQLPRSTKLKKPPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLASEVAALTRMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMVKVWQLSTAFTEQGPREVEDLDQLEAEITT
What is the function of this protein?
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways.  Inhibits the MAP3K7-induced NF-kappa-B activation pathway.  Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation.
What are the official names of this protein?
Cytoplasmic dynein 2 intermediate chain 2, Dynein 2 intermediate chain 2, WD repeat-containing protein 34.
What is the protein family that this protein belongs to?
Belongs to the dynein light intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, filopodium. Note=Concentrates around the centrioles and basal bodies also showing axonemal staining.
Protein: HEM6_ECOK1
Sequence: MKPDAHQVKQFLLNLQDTICQQLSAVDGAEFVEDSWQREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVYPRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG1_STRCO
Sequence: MAPRPLNEIVEAGWAKALEPVAGQITSMGEFLRAEIAAGRTYLPAGANVLRAFQQPFDDVRVLIVGQDPYPTPGHAVGLSFSVAPEVRPLPGSLVNIFRELNTDLNLPQPANGDLTPWTRQGVLLLNRALTTAPRKPAAHRGKGWEEVTEQAIRALAARGKPMVSILWGRDARNLRPLLGDLPALESAHPSPMSADRGFFGSRPFSRANDLLMRLGGQPVDWRLP
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase 1, UDG 1.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_SHIF8
Sequence: MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHDEERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_BURM9
Sequence: MARGKFITFEGIDGAGKTTHLQWFCDRLQERLGPTGRHVVVTREPGGTQLGETLREILLNQPMDLETEALLMFAGRREHLALVIEPALARGDWVVSDRFTDATFAYQGGGRGLPRDKLEALERWVQGGFQPDLTVLFDVQPQVASARRGAVRMPDKFESESDAFFARTRAEYLRRAHEAPHRFAIVDSSESIPQIRKQLEGVLAAL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.