PharMolix/UniProtQA huggingface dataset:
Protein: RL21_LISW6
Sequence: MYAIIETGGKQIKVEAGQEIYVEKLAGEVGDVVTFDKVLFVGGDSAKVGVPFVDGATVTAKVEKQGRAKKLTVYKYKPKKNYHKKQGHRQPYTKLTIDAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: MINC_BUCCC
Sequence: MKNKLITFKNNNFTALVIYLENINFKYFKKFLLKKIQKSPIFFKNIPIALNIEKLAFNFNWINLKKFFFSIGLFLIGIFGCKKESVKLDILKSGLPILFKKKKTLLNFNKKKNFFNKNSNKNHYSSLFIKNQKSYLVNELIRSGQRIYAPNTDLIITNNVSPGAELIADGNIHIYGNMKGRALAGAHGDETRKIFCTKLSAELISIAGEYCTVDQIPIKFLENSVEISLVNKKIFIKYNH
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: IFT56_CHLRE
Sequence: MFYSKSRPQHAARTNVAQAAANEKPKVPELEEFLTKRDYLGAIALLSFRRHANRNDLKNLEWLAYCYFHYGEHDKALVIYKELLQHEDPDPMFFVYSAACLYYMGMYKEAEEQALQGPKCALQTRILFHSAQRQGNDDKLMAYHGQLTDSIEDQLTLASIHYQRSHFQEATDIYKRLLLEHRDYLRSTVVYVALCYCKLDYYDVSLEILGVYLSAFPDSAIAVNLKACNHFRMYNGKAAEAELKTLAELSGGQHLDHDLIRHNLVVFRGGENALQVLPPLSDIPPEARLNLVIHHLRHHEVGEAFGLIKDMEPSTPPEFILKAVVHAMLGQVKGDPEHLKKAQQYYQLVGASASECDTIPGRQCMASCFFLLKQFEDVLVFLSSIKTYFLNDDDFNWNLGIAKAATGKYKEAEETLLQIANDKYRNEYTYTSWLARCYIMNGKARLAWERYLQLETNDESYQLLLLIANDCYKMGAFYFACKAFDVLERLDPAPEYLEGKKGAACGAFQMIVAGKEPKDLLRDVISLLRGNNSADQCEPIVAVMRKWAKNNGVKL
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium.  Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly.
What are the official names of this protein?
Intraflagellar transport protein 56, Abnormal dye filling protein 13, Tetratricopeptide repeat protein 26 homolog, TPR repeat protein 26 homolog.
What is the protein family that this protein belongs to?
Belongs to the IFT56 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum.
Protein: GATB_BURM9
Sequence: MTQWEVVIGLETHAQLSTVSKIFSGASTQFGAQPNTQACPVDLALPGVLPVLNRGAVERAIRFGLAIGATVAPRSVFARKNYFYPDLPKGYQISQYEIPVVQGGQITIQVPANEKAGKQAYSKTVNLTRAHLEEDAGKSLHEDFAGMTGIDLNRAGTPLLEIVTEPEMRSAAEAVAYAKALHGLVMWLGICDGNMQEGSFRCDANVSVRPVGQEKFGTRAEIKNLNSFRFLEDAINYEVRRQIELIEDGGEVVQETRLYDPDKRETRSMRSKEDAHDYRYFPDPDLMPLVIGADWIARVKGEMPELPAVMQQRFIEQYGVSAYDAGVLTSTKAMAEYFEALVAKAGAANAKLAANWLMGDVSSQLNRDGIDIDACPVSAAQLALVLQRIADGTISNKIAKEIFVTIWDEKAADEGAADRIIEAKGLKQISDTGALEAIIDEVLAANAKSVEEFRAGKDKAFNALVGQAMKATKGKANPQQVNELLKKKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: NDHI_CALVA
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CYSC_SALTY
Sequence: MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: ESXB_STAAE
Sequence: MGGYKGIKADGGKVDQAKQLAAKTAKDIEACQKQTQQLAEYIEGSDWEGQFANKVKDVLLIMAKFQEELVQPMADHQKAIDNLSQNLAKYDTLSIKQGLDRVNP
What is the function of this protein?
Virulence factor that is important for the establishment of infection in the host.  EsxB is required for EsxA synthesis as well as secretion (PubMed:15657139).  Mediates together with EsxA the release of S. aureus from the host cell.  Inhibits also host cytokine production and thus modulates dendritic cell-mediated immunity (By similarity).
What are the official names of this protein?
Type VII secretion system extracellular protein B, Ess extracellular protein B.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESAT-6 secretion system (Ess) / type VII secretion system (T7SS).
Protein: PO2F2_PIG
Sequence: MVHSSMGAPEIRMSKPLEAEKQGLDSPSEHTDTERNGPDTNHQNPQNKTSPFSVSPTGPSTKIKAEDPSGDSAPAGPPPPQAVQAHLSQVQLMLTGRQLAGDIQQILQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQAVTRPTLSDPHLSHPQPPKCLEPPSHPEEASDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSRPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPASYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGAAGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWNPAPYQP
What is the function of this protein?
Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3').  Regulates IL6 expression in B cells with POU2AF1.  Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression.  Modulates transcription transactivation by NR3C1, AR and PGR.
What are the official names of this protein?
POU domain, class 2, transcription factor 2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Oct-2, Octamer-binding transcription factor 2, OTF-2.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR11_OENGL
Sequence: MAKSIPSAGLRLRLRLRRNARRRSRKSTRKIPKGVIHVQASFHNTIVTVTDVRGRVISWSSAGTCGFKSTRKGTPFAAQTAAGDAIRPVVDQGMQRAEVRIKGPGLGRDAALRAIRRSGIRLSCIRDVTPLPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PUR7_XYLFM
Sequence: MLTTLLQSDLPGLPLRHCGKVRDVFDIPRKRLPVDTRSGEYLLIVATDRLSAFDVVLPDPIPGKGEILCQISNFWFQKTEHLMPNHLTGINVASVLPDGIDKTLYTQRAVVTKKLKPVGIEAIARGYLIGSGWKDYQRTGKVSGIQLPDGLQEAEKLPDPIFTPSTKAAVGHHDENIDFDTTVKMIGAELAERVRDATLRIYHFAAKYAAECGILLADTKFEFGTDIDGRLYVMDEMLTPDSSRYWPIDEYQVGTSPPSYDKQFVRNYLETLDWDKTAPGPTLPQDIIDRTRAKYTEALQRLAGINID
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SLX1_YEAS7
Sequence: MSQKIQQHQFPDFYCCYLLQSINKRQSFYVGSTPNPVRRLRQHNGKLAVGGAYRTKRDGSRPWEMIMIVRGFPSKIAALQFEHAWQHGYQTHYIAEKDRVVKHKAGGRTLHHKVALMKLLLKHEFFQRMNLIVEVFNIKAWEVWKQDKFFIERDRFPINIQINENALEEPKEKTVDVLMDHSDENLKVVEAVYTKVIENERNIFETFEKKLTTGVVRCEICEKEIDYTSEEQNLKPFVALCNNKDCGCVNHLKCLHRYFLDDEQLIVGRRNLIPRGGKCPKCDMFCDWTTLVKFSTRMKLAHGK
What is the function of this protein?
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.  Has a preference for simple Y, 5'-flap and replication fork-like structures.  It cleaves the strand bearing the 5'-non-homologous arm at the branch site junction and generates ligatable, nicked products from the 5'-flap or replication fork substrates.  Plays a critical role in maintaining the integrity of the ribosomal DNA (rDNA) loci, where it has a role in re-starting stalled replication forks.  Has Holliday junction resolvase activity in vitro.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYGB_YERPA
Sequence: MTQQTFLVEIGTEELPPKALRSLAESFAANFTAELDNANLSHGEVSWYAAPRRLAVKVANLSAAQADREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLVTDKGEWLLYRAHVKGQPAQLLLAGMVNTALSKLPIPKLMRWGDKETQFVRPVHTVTLLLGTEVIPGTVLGINSDRVIRGHRFMGEAEFTIDSADQYPQILLERGKVIADYELRKSIIKRDAEQAAQQIGGVADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYDTAGHLMPHFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFKTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWVAAQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLSLDLQTLTEEAVRLYGSKLTNAKVVDDVIEFMLGRFRAWYQDEGHSVDTIQAVLARRPTKPADFDARVKAVTYFRTLDAAAALAAANKRVSNILAKSTDTLNDHVHASILKEPAELKLATHLVVLRDQLEPVFAAGQYKEALVELAALRETVDEFFESVMVMAEDDAVRVNRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BL1S1_HUMAN
Sequence: MAPGSRGERSSFRSRRGPGVPSPQPDVTMLSRLLKEHQAKQNERKELQEKRRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKEIGDVENWARSIELDMRTIATALEYVYKGQLQSAPS
What is the function of this protein?
May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation.  May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 1, BLOC-1 subunit 1, GCN5-like protein 1, Protein RT14.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S1 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Mitochondrion matrix. Cytoplasm, cytosol. Lysosome membrane.
Protein: DXR_PSEA7
Sequence: MSRPQRISVLGATGSIGLSTLDVVQRHPDRYEAFALTGFSRLAELEALCLRHRPVYAVVPEQAAAIALQGSLAAAGIRTRVLFGEQALCEVASAPEVDMVMAAIVGAAGLPSTLAAVEAGKRVLLANKEALVMSGALFMQAVKRSGAVLLPIDSEHNAIFQSLPRNYADGLERVGVRRILLTASGGPFRETPLEQLASVTPEQACAHPNWSMGRKISVDSASMMNKGLELIEACWLFDAQPSQVEVVIHPQSVIHSMVDYVDGSVIAQLGNPDMRTPISYAMAWPERIESGVAPLDMFAVGRLDFQRPDEQRFPCLRLARQAAETGGSAPAMLNAANEVAVAAFLERHIRFSDIAVIIEDVLNREAVTAVESLDQVLAADRRARSVAGQWLTRYAG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: SYDND_RHOP5
Sequence: MHRYRSHTCGALRESHIDQTVRVSGWCHRIRDHGGLLFIDLRDHYGLTQCVADPDSPAFKDAEKLRAEWVVKIDGKVRRRPEGTDNADLPTGQVEIFITEIEVLGPAGELPLPVFGEQEYPEDIRLKYRFLDLRREKLHQNIMTRGAIVDSMRKRMKEQGFFEFQTPILTASSPEGARDFLVPSRIHPGRFYALPQAPQQYKQLLMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDVEMSFITQEDVFAAMEPVITGVFEEFAKGKRVNSVWPRIPFAEAMQKYGSDKPDLRNPIEMQDVSEHFRGSGFKVFARMLEEPRNQVWAIPGKGGGSRAFCDRMNSWAQGEGQPGLGYIMWREGNEGAGPLANNIGPERTEAIRIALGLGAGDAAFFVAGDPAKFVRFAGLARTRVGEELNLVDKEQFALAWVVDFPMYEYNEDDKKVDFSHNPFSMPQGGMEALVTQDPLNIKAFQYDITCNGFEIASGGIRNHRPEAMVKAFEIAGYGEQEVVDRFGGMYRAFQYGAPPHGGMAAGVDRIVMLLCGTNNLREISLFPMNQRAEDLLMGAPSEVTPKQLRELHIRLNLQEE
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPB4_DEBHA
Sequence: METREGSLTWSVLKCDLHPWIKEAIKSLGYPTMTPVQASTIPLFSGNKDVVVEAVTGSGKTLAFVIPVLQKLSNRLYNIDEEGENPEPVKKGHMLSIILSPTRELAKQIQTVFDKVLEYIPEDKATIKTQLLVGSLSSVREDIDYFLTNKTHILIATPGRLLDFLSSNYVKTNSVEIAVLDEADKLLDISFERDVIKILKQLPKQRRTGLFSATISSAGDTIFRTGMANPVKIVVKSKNSKNAAPTSLNVSYMHVEPETKISALIALIKDYRFQKCIVYFPTCTSVKHFYSVFQTLVNVEEEDRYKFFSLHGQLSTKPRLKTLQNFSEGDSMLHKHVLLTTDVAARGIDIPDVDLVIQLDPPTDPDVFFHRSGRTGRANKVGQAIVMLNNNSREEDYVNFMEVKGMTMSNMECPNISKIHDKFQKKFRKYMLEDRARHELAIKSYVGFVRYYSKHMASSIFRLQTLDYVGLGKMYGLLRLPKMPESRYIPNEEMPEDGWLGDVIDMDKYEYADKQKEESRKKNLEEDKARKVHDAKKRKELKVKNEAWSSKTDKIETKQERREKMKRKREAIEKQLMDDSSSDEETKVDWKEMVKTNKKKKTPSDSMQGSFDDL
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase SPB4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: AHL20_ARATH
Sequence: MANPWWTNQSGLAGMVDHSVSSGHHQNHHHQSLLTKGDLGIAMNQSQDNDQDEEDDPREGAVEVVNRRPRGRPPGSKNKPKAPIFVTRDSPNALRSHVLEISDGSDVADTIAHFSRRRQRGVCVLSGTGSVANVTLRQAAAPGGVVSLQGRFEILSLTGAFLPGPSPPGSTGLTVYLAGVQGQVVGGSVVGPLLAIGSVMVIAATFSNATYERLPMEEEEDGGGSRQIHGGGDSPPRIGSNLPDLSGMAGPGYNMPPHLIPNGAGQLGHEPYTWVHARPPY
What is the function of this protein?
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity).  Negatively regulates plant innate immunity (PTI) to pathogens through the down-regulation of the PAMP-triggered NHO1 and FRK1 expression (PubMed:20738724).
What are the official names of this protein?
AT-hook motif nuclear-localized protein 20.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_ROUAM
Sequence: MTNIRKTHPLFKIINDSLVDLPTPSSISSWWNFGSLLGICLGIQILTGLFLAMHYTSDTATAFQSVTHICRDVNYGWVLRYLHANGASMFFICLFLHVGRGLYYGSYIFTETWNVGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIIAALVIVHLLFLHETGSNNPTGIPSDMDMIPFHPYHTIKDALGMLAMILVLLMLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALMPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFSLILILMPLISIMENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RLMN_CAMJR
Sequence: MKELVNILDFLPEELGEKIKPMFRVKQIYQWIYQKYANNFSDMSSLPKDLRLELAQNFHFSPVKCVKNEQSKDGSIKYLFELVDGLRIESVLLPMKEEKIDAEGKRISHARYTICVSSQVGCKSGCSFCLTAKGGLKRNLSAGEIVGQILWIKKQNNIPYERRINIVYMGMGEPLDNLKNVSKAVKILAQNEGLAISPRRQTISTSGLAKQIKELGQMNLGVLLAISLHAVNDELRTELMPINKAYNIAAIMDAVREFPIDQRKRVMFEYLLIDGINDKLEHAKELVKLLNGIKAKVNLILFNPHEGGLYKRPSLENAIKFQDLLSNKGVTCTIRESKGLDISAACGQLKERAKEQ
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KIF17_HUMAN
Sequence: MASEAVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEAEKQLIREEYEERLARLKADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRKETEAVLQVGVLYKAEVMSRAEFASSAEYPPAFQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAELPKVEPSKSEISLGSSESSSLEETSVSEAFPGPEEPSNVEVSMPTEESRSRYFLDECLGQEAAGHLLGEQNYLPQEEPQEVPLQGLLGLQDPFAEVEAKLARLSSTVARTDAPQADVPKVPVQVPAPTDLLEPSDARPEAEAADDFPPRPEVDLASEVALEVVRTAEPGVWLEAQAPVALVAQPEPLPATAGVKRESVGMEVAVLTDDPLPVVDQQQVLARLQLLEQQVVGGEQAKNKDLKEKHKRRKRYADERRKQLVAALQNSDEDSGDWVLLNVYDSIQEEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLLQQLLEQVQPLIRRDCNYSNLEKILRESCWDEDNGFWKIPHPVITKTSLPVAVSTGPQNKPARKTSAADNGEPNMEDDRYRLMLSRSNSENIASNYFRSKRASQILSTDARKSLTHHNSPPGLSCPLSNNSAIPPTQAPEMPQPRPFRLESLDIPFTKAKRKKSKSNFGSEPL
What is the function of this protein?
Dendrite-specific motor protein which, in association with the Apba1-containing complex (LIN-10-LIN-2-LIN-7 complex), transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules.
What are the official names of this protein?
Kinesin-like protein KIF17, KIF3-related motor protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium. Cell projection, dendrite. Note=Localizes to dendrites of pyramidal neurons (By similarity). Does not localize to the axons or nuclei in cerebral cortex, hippocampus or olfactory bulb (By similarity). Co-localizes with NR2B-containing vesicles along microtubules (By similarity).
Protein: SECF_GEMAT
Sequence: MLRIFHNTKYEFVRWWRVAAGLTLAFIAAGFVSFAVTGGVNYSIEFTGGTLMQLQFKTPPDVAEVRSALDAAGIQGAEIQQFGANTDFTIRARDEKQVEAQDAGAEGISRQITAALDAKFGAGTVTIVRTEAVGPKVGAELRTGAAMAMLIASIFTLIYLAIRFDWRFGLAAVLSTTHDILITLAFIKIFHIEVSLTVVAAILTLVGYSANDTIIIFDRVRENLKKPHKGETLSHILDRSINETLPRSIMTHTTTFSATLALLLLAGEVIRPFAWVMAFGVVMATFSSIYVAGPLLLWIEGRWPRLDDAATARAVRAGEAATTTARGTDRVSAR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1580_METJA
Sequence: MLIKILEEKLMELIQIVGVIFALFALSRVVLQLKRRSISFNEGLFWIFVWGFVVIFLVFPEFFGYVAEVLGVGRGVDALIYISIVVLFYLIYRLYAKINNLERQITHIVREIAIRDRYEPKKRD
What are the official names of this protein?
Uncharacterized protein MJ1580.
What is the protein family that this protein belongs to?
To M.thermoautotrophicum MTH137.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EOLAL_PONAB
Sequence: MKFGCLSFRQPYAGFVLNGVKTVETRWRPLLSSQRNCTIAIHIAHRDWEGDAWWELLVERFGMTPAQIQALLREGEKFGRGVIAGLVDIGETLQCPEDLTPDEVVELENQAVLTNLKQKYLTVISNPRWLLEPIPRKGGRDVFQVDIPEHLIPLGHEV
What are the official names of this protein?
EOLA-like protein.
What is the protein family that this protein belongs to?
Belongs to the EOLA family.
Protein: PPK1_KLEPN
Sequence: MGQEKLYIEKELSWLAFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFAELKRRIIISEEQGLNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEMARNQIFLINERQLSVNQQNWLRHYFKHYLRQHITPILINRETDLVQFLKDDYTYLAVEIIRGESIRYPLLEIPSDKVPRFVNLPPETPRRRKPMILLDNILRYCLDDIFKGFFDYDALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQPDAEPVRFVYQRDMPDAMVEMLRDKLTISRYDSIVPGGRYHNFKDFIGFPNVGKANLVNKPLPRLRHLWFDKFRNGFDAIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDAMIHAAHNAKKVTVVVELQARFDEEANIHWARRLTEAGVHVIFSAPGLKIHAKLFLISRKEGDDVVRYAHIGTGNFNEKTSLIYTDYSLLTADARITNEVRRVFNFIENPYRPVSFDYLLVSPQNSRRLLYDMIDKEIANAQKGLSSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLIRGMCSLIPELEGISDNIRVISIVDRYLEHDRIYIFDNAGDKQVYLSSADWMTRNIDYRIEVAAPLLDPRLKQQILDIIEILFSDTVKARYIDKELSNRYVPRGNRRKVRSQLAIYDYIKSLEQPD
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: CSRA_XYLFT
Sequence: MLILTRRSGETLMIGDQVTVTVLGVKGNQVRVGINAPKHVAVHREEIYHRIQRGDELACSSGTRGDSGSSI
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.