PharMolix/UniProtQA huggingface dataset:
Protein: RS10_CLOB6
Sequence: MAKQKIRIRLKAFDHSLLDQSALKIVETAKTTGAKVAGPVPLPTEKDIVTILRAPHKYKDAREQFEIRTHKRLIDIISPSPKTVDALMRLDLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: TLP_BACSU
Sequence: MTKNQNQYQQPNPDDRSDNVEKLQDMVQNTIENIEEAEASMEFASGEDKQRIKEKNARREQSIEAFRNEIQDESAARQNGYRS
What are the official names of this protein?
Small, acid-soluble spore protein Tlp.
What is the protein family that this protein belongs to?
Belongs to the Tlp family.
What are the subcellular locations of this protein?
Spore core.
Protein: LEU1_TOLAT
Sequence: MSDRVIIFDTTLRDGEQALPASLTVREKLQIALALERLGVDVMEVGFPVSSPGDFESVQTIARQIKNSRVCALSRALQKDIDAAAEALKVADQFRIHTFLATSTIHVESKLKKSFEDVLEMGINAVKYARRFTDDVEFSCEDAGRTPIDNLCRMVEAAINAGARTINIPDTVGYTIPSEFGGIIHNLFNRVPNIDKAVISVHCHDDLGLSVANSISAVQMGARQVECTINGIGERAGNTSLEEVAMILRTRQDLIGVHTNIKHQEIHRTSQLVSQLCNMPVQPNKAIVGANAFSHSSGIHQDGVLKAKNTYEIITPESVGLNQNTLNLTSRSGRHVIKHRLALLGYPEGSYDLDQIYTSFLQLADKKGQVFDYDLEALLFFSQIQEEPEHFKLNYLSVQSGGSIMATASVRMKVGDEEVTEAATGNGPVDAVYQCINRITGYEINISKYDLKSKGIGKDALGQVDIVAEFKGRKFHGMGLATDIVESSAQALVHVINNIYRALQVAEHKERFAQKTVMETL
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: MSX1_LEORO
Sequence: MTSLPLGVKVEDSAFGKPAGGGSGQSPSSAAATAAAVGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESSLAASESAQAAGGLAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT
What is the function of this protein?
Acts as a transcriptional repressor.  May play a role in limb-pattern formation.  Acts in cranofacial development and specifically in odontogenesis (By similarity).
What are the official names of this protein?
Homeobox protein MSX-1, Msh homeobox 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COW1_CONLT
Sequence: MGKLTILLLVAAALLSTQVMVQGGGDQPAARNAVPRDDNPDGMSGQFMNVLRRSGCPWEPWCG
What is the function of this protein?
Its target is unknown, but this toxin may modulate voltage-activated calcium channels (Cav) or calcium-dependent potassium channels (KCa).
What are the official names of this protein?
Contryphan-Lt.
What is the protein family that this protein belongs to?
Belongs to the O2 superfamily. Contryphan family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEQA_ECOLI
Sequence: MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFSAASQPAAPVTKEVRVASPAIVEAKPVKTIKDKVRAMRELLLSDEYAEQKRAVNRFMLLLSTLYSLDAQAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMIEHIMQSMQFPAELIEKVCGTI
What is the function of this protein?
Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle.  Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins.  Repression is relieved when the region becomes fully methylated.  Can also bind to hemimethylated GATC sequences outside of oriC region.  Binds, with less affinity, to fully methylated GATC sites and affects timing of replication.  May play a role in chromosome organization and gene regulation.
What are the official names of this protein?
Negative modulator of initiation of replication.
What is the protein family that this protein belongs to?
Belongs to the SeqA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localization is cell cycle-dependent. Localizes at midcell in newborn cells, then migrates in opposite directions toward cell quarter sites and remains tethered there until the cell divides.
Protein: LGT_WIGBR
Sequence: MLNCYLAFPKYDPIIFSVGRFSAHWYGLMYLIGFYFIMWSSIKRYKLISLNKEKIENILYFSFLNALIGGRIGYVIFYKTKEIFFNPYFIFKVWEGGMSFHGGLLGSIISIYYFSKKYNCKFFKISDFLVPLIPFGLGFGRIGNFINGELWGRVNTSFCFTMLFPGSYDEDVKFLLNNPHLQDVFDKYHLLPRHISQLYEMFLEGILLFIILNIFEKKKKPTGYMSGLFLILYGSFRIIAEFFRQPDPQIGLMFNYISLGQILSIPMILYGLILIINSK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIE_LEGPH
Sequence: MTNQKQTTHFGFKSVDWNEKEKKVAEVFHSVAKNYDRMNDLMSLGIHHLWKRYTIELSHVRPGQSVLDLAGGSGDLTRLLLQKVGDSGQVILADINAAMLHVGRDRLLDEGLFKNIRYVQGNAQCLPFADNSFHCITMGFGLRNVTDKDEALQSMYRVCKPGGKLMVLEFSTPVFPGLKPVYDWYSFNILPKIGKFVANDEASYQYLAESIRMHPDQETLKAMIERVGFEDCHYHNLSGGIVALHIAYKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SYE_NITEU
Sequence: MVKTRFAPSPTGYLHIGGARTALFSWAFARKQGGKFVLRIEDTDLERSTQQSVQAILDGMAWLGLDYDEGPYYQMQRLNRYQEVAEQLLTQGLAYQCYASREELDALREQQRLAGLKPRYDGRWRDSRQTPPAGVKPVVRLKTPQHGYVVFDDLVKGKISVANHELDDLVLLRSDGTPTYNFGVVLDDLDMGITHVIRGDDHVNNTPRQINILKALGAAIPQYAHVPMILGADGERLSKRHGAVSVMHYRDQGYLPEALINYLARLGWSHGDEEIFSREQLVEWFDLAAISRSPAKFNPEKLTWLNQHYLKMADDARLVELVMPFLLERNYPLPATENLLKIVNLLKDRASTIEELADASAYFFRTIEPPEELRTQYFTAEIRPVLEYLVDRLAQIEWKRETIHHEIKQTVSSHNLKFPSLAMPLRVMVTGEAQTPAIDAVLELLGKEETLHRLRGRMEIFPG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNN_RHIE6
Sequence: MTHEPHPGAGAERGIMVVVVGPSGAGKDTLMNLAARHFSGRADVHFTRRVITRHRGAGGEDHLSVSLQGFAAMEQSGSFAVWWEAHGLKYGIPAEVSVALSKGHIVVANGSRSALHRFQAAFPRLKVINVTASAEVLAGRLEARGRETHEDIMARLARGPLTVRGDYDVTELDNSGSIEEAEQKMIAILDGLLAEVH
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: ATPA_LOLPR
Sequence: MATLRVDEIHKILRERIEQYNRKVGIENIGRVVQVGDGIARIIGLGEIMSGELVEFAEGTRGIALNLESKNVGIVLMGDGLMIQEGSFVKATGRIAQIPVSEAYLGRVINALAKPIDGKGEIIASESRLIESPAPSIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQNVICVYVAIGQRASSVAQVVTNFHEEGAMEYTIVVAEMADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNSLLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSSDLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELQAFAQFASALDKTSQNQLARGRRLRELLKQSQANPLPVEEQIATIYTGTRGYLDSLEIEQVNKFLDDLRKHLKDTKPQFQEILSSSKTFTEQAEILLKEAIQEQLERFSLQQQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: NU6M_CERCA
Sequence: MMQLMLYASTLITSIILFKMNHPLAMGLMLLIQTIQISMLTGLMAKSFWFSYILFLIFLGGMLVLFIYVTSLASNEMFSLSMKLTTISLFIFSMILIINILLDKSSISFFIQNNEMQSIYNLNMFLQENSLNLQKLYNYPTNLMTILLMNYLLITLIAVVKITKLFYGPLRPMN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: KTHY_PYRAE
Sequence: MAFVAIEGIDGSGKSTVISLLEKKLPRVYATREPSSGPIGRLIKEWALKGGSVDPHVDALLFAADRIEHYKREIEPRVREGYIVISERYIESSIAYQGAAGVSREFVKYINSLVPKPDLTIILDVDPSIAEARIRQRGGAEKYEYLSFLRKVREIYLARAAEEGYPVIDASRRPEEVAADVAELIKRVVRFK
What are the official names of this protein?
Probable thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: Y096_METFK
Sequence: MLITIPEVFTPEEAESIRQRLDATEWLDGKVTAGYQSAKAKNNLQLAENHPLAIELGDLIVSRLTQHPLFMSAALPRKVFPPLFNRYESGQSFGFHIDNAVRSLSGSRERVRTDLSSTLFFTPPEDYDGGELIRHASNQIARGTYGAVSRHQPAQGHAGDPGGTHLIFLLDPEPDP
What are the official names of this protein?
PKHD-type hydroxylase Mfla_0096.
Protein: RK20_OENAR
Sequence: MTRIRRGYIARRRRTKTRFFASSWRGARGNLTRAIIQQRIRAWFSSHRDRTRQKRDFRRLWITRINAAIRENGRSSIYSKLIHNLYKRQLFLNRKMLAQLAILNRNCLYMISNQILKEVDWQESATILEI
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BIOD_PSET1
Sequence: MKEFFITGTDTDAGKTHVTSLLLKLLAQHKKQAIGFKPLASGCEMAFDQLVNADALILMESATVSAKYDIINPFAFAPAIAPHIAAEQAGVTITADKLSSAYKNVKQQGADYILTEGAGGWALPISNTDYLYNWVKAEQLPVILVVGMKLGCLNHALLTAAHMQSMGINCIGWIANQVDPNMDEYQANLDSLKLRLPFPILAISPYSEQTPKLQIYKTLLENFALNT
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPAP_HCMVM
Sequence: MDRKTRLSEPPTLALRLKPYKTAIQQLRSVIRALKENTTVTFLPTPSLILQTVRSHCVSKITFNSSCLYITDKSFQPKTINNSTPLLGNFMYLTSSKDLTKFYVQDISDLSAKISMCAPDFNMEFSSACVHGQDIVRESENSAVHVDLDFGVVADLLKWIGPHTRVKRNVKKAPCPTGTVQILVHAGPPAIKFILTNGSELEFTANNRVSFHGVKNMRINVQLKNFYQTLLNCAVTKLPCTLRIVTEHDTLLYVASRNGLFAVENFLTEEPFQRGDPFDKNYVGNSGKSRGGGGGSGSLSSLANAGGLHDDGPGLDNDIMNEPMGLGGLGGGGGGGGKKHDRGGGGGSGTRKMSSGGGGGDHDHGLSSKEKYEQHKITSYLTSKGGSGGGGGGGGGGLDRNSGNYFNDAKEESDSEDSVTFEFVPNTKKQKCG
What is the function of this protein?
Accessory subunit of the DNA polymerase that plays an essential role in viral DNA replication and acts by increasing the processivity of polymerization.  Forms dimers that binds to double-stranded DNA and UL54 specifically to stimulates long chain DNA synthesis efficiently.  Plays an important role in maintaining the structure of viral replication compartments by interacting with host nucleolin/NUC.  In addition, suppresses innate immune responses through effects on host IRF3 and NF-kappa-B.  Mechanistically, interfere with the binding of IRF3 and the p65 NF-kappa-B subunit to the promoters of antiviral genes, thereby inhibiting the expression of these genes.
What are the official names of this protein?
DNA polymerase processivity factor, Polymerase accessory protein, PAP, Protein ICP36.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae polymerase accessory protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: AGLG_RHIME
Sequence: MNPSRRSPLTWAVHLSVLLLVLLWTLPTAGLLISSLRDKDQLAVSGWWTALSSSSRNAVVRAPSAEDQVERDGKFVISGNLLEGRGEVSAFGFSSREPTKFKPGETAELNDGERLTVQSDGSFEIVSDQRMEGSRGQRIFFTATTPPRFTLDNYAEVLSAAGIGRSFLNSLTVAVPSTVIPILIAAFAAYALAWMPFPGRAVLLAVVVGLLVVPLQMSLIPLLQLYNGVGAFFGVSAKTYMGIWLAHTGFGLPLAIYLLRNYMAGLPREIMESARVDGASDFDIFVKIILPLSFPALASFAIFQFLWTWNDLLVAIVFLGAGDDKLVLTGRLVNLLGSRGGNWEILTASAFITIVVPLIVFFALQRYLVRGLLAGSVKGG
What is the function of this protein?
Part of the binding-protein-dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Alpha-glucoside transport system permease protein AglG.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTHR1_SCHPO
Sequence: MKISDKLLHPDWKEKVTYSYEFFPPKTSTGVQNLYNRIDRMKTWGRPMFVDVTWGAGGTSSELTPGIVNVIQTDFEVDTCMHLTCTNMSTEMIDAALKRAHETGCRNILALRGDPVKDTDWTEGESGFRYASDLVRYIRTHYNDEFCIGVAGYPEGYSPDDDIDESIKHLKLKVDEGADFIVTQMFYDVDNFIAWVDKVRAAGINIPIFPGIMPIQAWDSFIRRAKWSGVKIPQHFMDTLVPVKDDDEGVRERGVELIVEMCRKLIASGITRLHFYTMNLEKAVKMIIERLGLLDENLAPIVDTNNVELTNASSQDRRINEGVRPIFWRTRNESYVSRTDQWDELPHGRWGDSRSPAFGEFDAIRYGLRMSPKEITTSWGSPKSYSEIGDLFARYCEKKISSLPWSDLPISDEADLIRDQLLSMNRNAFLTINSQPALNGEKSSHPVFGWGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLNSVSYFVTNKNGDLDTNSQYEIPNAVTWGVFPNREIIQPTIVESTSFLAWKDEAYSLGMEWANAYSPDSISRKLLVSMMKEWFLCVIVDNDFQNGQSLFDVFNKMRSLKDIHPELYYANAS
What is the function of this protein?
Major methylenetetrahydrofolate reductase required to generate the methyl groups necessary for methionine synthetase to convert homocysteine to methionine.  Performs 80 to 85 percent of the total methylenetetrahydrofolate reductase activity of the cells.
What are the official names of this protein?
Methylenetetrahydrofolate reductase 1.
What is the protein family that this protein belongs to?
Belongs to the methylenetetrahydrofolate reductase family.
Protein: YG21A_YEAST
Sequence: MESQQLHQNPHSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDLKNQHSEIPQAKTKVGNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDDELSLRPATERI
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty2-GR1 Gag polyprotein, TY2A, TYA, Transposon Ty2 protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM3_EBVG
Sequence: MLYASQRGRLTENLRNALQQDSTTQGCLGAETPSIMYTGAKPDRWAHPLVGTIHASNLYCPMLRAYCRHYGPRPVFVASDESLPMFGASPALHTPVQVQMCLLPELRDTLQRLLPPPNLEDSEALTEFKTSVSSARAILEDPNFLEMREFVTSLASFLSGQYKHKPARLEAFQKQVVLHSFYFLISIKSLEITDTMFDIFQSAFGLEEMTLEKLHIFKQKASVFLIPRRHGKTWIVVAIISLILSNLSNVQIGYVAHQKHVASAVFTEIIDTLTKSFDSKRVEVNKETSTITFRHSGKISSTVMCATCFNKNSIRGQTFHLLFVDEANFIKKEALPAILGFMLQKDAKIIFISSVNSADQATSFLYKLKDAQERLLNVVSYVCQEHRQDFDMQDSMVSCPCFRLHIPSYITMDSNIRATTNLFLDGAFSTELMGDTSSLSQGSLSRTVRDDAINQLELCRVDTLNPRVAGRLASSLYVYVDPAYTNNTSASGTGIAAVTHDRADPNRVIVLGLEHFFLKDLTGDAALQIATCVVALVSSIVTLHPHLEEVKVAVEGNSSQDSAVAIASIIGESCPLPCAFVHTKDKTSSLQWPMYLLTNEKSKAFERLIYAVNTASLSASQVTVSNTIQLSFDPVLYLISQIRAIKPIPLRDGTYTYTGKQRNLSDDVLVALVMAHFLATTQKHTFKKVH
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 3, Terminase large subunit.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM3 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Responsible for the nuclear localization of the two others subunits TRM1 and TRM2.
Protein: RL3_VIBA3
Sequence: MIGLVGRKVGMTRVFTEEGVSIPVTVVEVEANRISQVKTLETDGYAAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLENGEEFEVGAELNVELFNEIKKVDVTGTSKGKGFQGAIKRWNFSTQDMTHGNSLSHRAPGSIGQCQTPGRVFKGKKMAGHMGAERVTTQNLEIVRVDAERNLLLIKGAVPGSTGGNVIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HSCB_BURMS
Sequence: MVSLKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAYQTLRDPLKRATYLLHLRGVDVGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVERVSAEIGAQIERLEH
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: HBAD_PHACA
Sequence: MLGAEETALVRGVWQKVESAKDEMGEETLTRMFLVYPKTKTYFPHFDLHHGSEQIRNHGKKVVTALGNAIQNLDNLRQTLADLSNLHAYNLRVDPVNFKLLAQCFQVVLAVHLGQEYTPEVHVAFDKFLTAVAAVLAEKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-D, Alpha-D-globin, Hemoglobin alpha-D chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GLCE_HUMAN
Sequence: MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQFPRRSSSGFRVDGFEKRAAASESNNYMNHVAKQQSEEAFPQEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNKPNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN
What is the function of this protein?
Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains.  This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins.
What are the official names of this protein?
D-glucuronyl C5-epimerase, Heparan sulfate C5-epimerase, Hsepi, Heparin/heparan sulfate:glucuronic acid C5-epimerase, Heparosan-N-sulfate-glucuronate 5-epimerase.
What is the protein family that this protein belongs to?
Belongs to the D-glucuronyl C5-epimerase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: DEF38_ARATH
Sequence: MASSKNGTVLFVSLMILLLISTGVKAYCERVRSRSAPHDICKKKNGNAVCKEKCWTIEKYQNGRCLILPKTTKLDCYCYHFDQC
What are the official names of this protein?
Putative defensin-like protein 38.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: OPSB_PANTR
Sequence: MRKMSEEEFYLFKNISSVGPWDGPQYHIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTVSSTQVGPN
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal (By similarity).  Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors (By similarity).  Involved in ensuring correct abundance and localization of retinal membrane proteins (By similarity).  May increase spectral sensitivity in dim light (By similarity).
What are the official names of this protein?
Short-wave-sensitive opsin 1, Blue cone photoreceptor pigment, Blue-sensitive opsin, BOP.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Cytoplasm, perinuclear region.
Protein: POA1_YEAST
Sequence: MSNITYVKGNILKPKSYARILIHSCNCNGSWGGGIAYQLALRYPKAEKDYVEVCEKYGSNLLGKCILLPSYENSDLLICCLFTSSFGGSSHGEKQSILNYTKLALDKLKTFREAKDKTRTSEDSIGDYLNGHIKYPIGEYKLEMPQINSGIFGVPWKETERVLEEFSGDMSFTVYQL
What is the function of this protein?
Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.  Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety.  Inactive towards proteins bearing poly-ADP-ribose.
What are the official names of this protein?
ADP-ribose 1''-phosphate phosphatase, [Protein ADP-ribosylglutamate] hydrolase.
What is the protein family that this protein belongs to?
Belongs to the POA1 family.