PharMolix/UniProtQA huggingface dataset:
Protein: PLIAA_GLOBS
Sequence: HETDPDGHVLNSLMLIVMKFQREFSNLKDAFMTVHKARSFGSGSERLYVTNKEVGNFEGLGEICRQAGGRIPSPQLKNQNKAFANVLERHNKEAYLVVGNSANFTNWAEGQPKKADGTCVKADTHGLWHSTSCDDNLLVVCEFYFIL
What is the function of this protein?
Inhibits the enzymatic activity of the acidic phospholipase A2 (PLA2).
What are the official names of this protein?
Phospholipase A2 inhibitor subunit A, alpha-PLI A.
What is the protein family that this protein belongs to?
Belongs to the alpha-type phospholipase A2 inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in plasma.
Protein: BLVRB_BOVIN
Sequence: MVVKKIALFGATGNTGLTTLAQAVQAGYEVTVLVRDPSRLPSEGPQPAHVVVGDVRQPADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGAQNIVAAMKAHGVDKVVACTSAFLLWDPSKVPPRLQDVTDDHIRMHKVLQQSGLKYVAVMPPHIGDHPLTGAYTVTLDGRGPSRVISKHDLGHFMLHCLTTDKYDGHTTYPSHVYE
What is the function of this protein?
Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone).  Contributes to heme catabolism and metabolizes linear tetrapyrroles.  Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH.  In the liver, converts biliverdin to bilirubin.
What are the official names of this protein?
Flavin reductase (NADPH), FR, Biliverdin reductase B, BVR-B, Biliverdin-IX beta-reductase, Green heme-binding protein, GHBP, NADPH-dependent diaphorase, NADPH-flavin reductase, FLR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_SHISS
Sequence: MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PR8A8_MOUSE
Sequence: MELQFRQPHFSDALLLLLLSNLLLWEKASSIPACMAEKSGCWNPRMETFDSAIRKAETLRTVSKQFYVELYHNQFSSGKFATLTSKLVRRDEIVFRAASHCHSTLTNPPNKGIQYITIEIPEYLKTLINYVGAWISPLFHLVIELSAMKDVPETILSKAKEIEENNRQILRDLRWIITEVYPTSKKKEIFPSWELLSFLKSSSRNSKFLAMFNLSHCLEYDTQFFLFHLRILKCRITGKDC
What are the official names of this protein?
Prolactin-8A8, Placental prolactin-like protein C3, PLP-C3, PRL-like protein C3, Prolactin-like protein C-gamma, PLP C-gamma.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAK_CLOK5
Sequence: MSKVIGIDLGTTNSCVAVMEGGDPVVIANSEGARTTPSVVSFQANGERLVGQVAKRQSITNPDKTIISIKREMGTNHKVNIDGKQYTPQEISAMVLQKIKADAEAYLGETVTQAVITVPAYFNDSQRQATKDAGKIAGLEVLRIINEPTAAALAYGMDKMDTNQKIFVYDLGGGTFDVSILELGDGVFEVKATNGDTHLGGDDFDKKIIDYIADTFKADNGIDLKNDKMALQRLKEAAEKAKIELSSSTQTNINLPFITADATGPKHIDMSLTRAKFNELTQDLVDRTIEPMKKALNDAGLTINDINKVILVGGSTRIPAVQEAVKSFTGKEPSKGVNPDECVAMGAAIQAGVLTGDVKDVLLLDVTPLTLGIETLGGVATPLIERNTTIPTKKSQVFSTAADGQTSVEIHVVQGERQMAADNKTLGRFTLSGIAPAPRGVPQIEVTFDIDANGIVNVSAKDKGTGKEANITITASTNLSDDEIDKAVKEAEKFEEQDKKRKESIEIKNNADQVVYQTEKTLKDLGDKVSSEDKKAIEEKVEAVKKVKDGDDLEAIKKATEDLTQTFYGISSKIYSQNAEPGADGGANSGANPGGTTGNTDTKDDNVVDAEYKVDDDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: DCD_LEPCP
Sequence: MSIKSDKWIRRMAQESGMIEPFEPGQVRQSADGQKIVSYGTSSYGYDIRCAREFKVFTNIYSTVVDPKNFDEKSFVDIESDVCIIPPNSFALARTMEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGCAQVLFFESDEVCETSYRDRGGKYQGQTGVTLPKT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: SYFA_CLOBB
Sequence: MKEKLKELQELAIKQIENSIKSNELEEIRVKFLGKKGELTTILRGMGGLSPEERPLVGKLVNEAKAKVEEKLESAIKKIKDKEKAEKLAGETIDISLPGKKQVIGKSHPLELTLKNMEDIFVSMGFTIEEGPEVEYDHYNFEALNIPKNHPARSEQDTLYINDNIVLRTQTSPVQVRTMENQKPPIKMISPGKVYRSDSVDATHSPIFYQMEGLVIDKGVTFADLKGTLELFAKKMFGDKVETKFRPHHFPFTEPSAEMDATCFVCGGEGCRVCKNSGWIELLGCGMVHPNVLRNCGIDPEVYSGFAFGFGVDRMVMLKYGIDDIRLLYESDMRFLNQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_YERE8
Sequence: MQQRRPIRRALLSVSDKAGIIEFATALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHDIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIIAELDENDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGALVPAYHGDTEQPSGRFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVATALQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIADSLLAAYDKAYKTDPTSAFGGIIAFNRELDAETASAIISRQFVEVIIAPSVSTEALALLAAKQNVRVLTCGQWQERSAGLDFKRVNGGLLVQDRDLGMVTEADLRVVSQRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHGIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: COL38_CAEEL
Sequence: MSKYLVPVCASISLVAVFGALVAMHSIVVDIDTMREEIVTGVHDMKVMSDDAWNRMIGFTKPSLDSESRSAAFASVFRNKRSAYPSQCNCDANSQGCPPGPPGPPGLPGGRGDQGPSGDKGRDGASGVSLAVTHHLPGGCIQCPQGPPGETGPDGDIGEPGFPGASGSAGQCGEDGAPGEAGITGEQGPQGEPGTEGSEGPTGQDGTIGGPGLPGQPGTPGWPGSQGEPGKNGDSGVDGEQGPQGPQGPDGQPGRDADNGQPGLPGKDGSIGPDANYCPCPARAKKH
What is the function of this protein?
Probable cuticular collagen-like protein (Probable).  Nematode cuticles are composed largely of collagen-like proteins (Probable).  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (Probable).  Acts downstream of the Wnt signaling pathway, perhaps in the formation of the adult cuticle (PubMed:24569038).
What are the official names of this protein?
Cuticle collagen 38.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUB_CAMC5
Sequence: MNAIFVANKPTGLSSNQFLNRLKRKYGVKKAGFSGTLDPFASGCLIVAFGSYTKFFRFLDKTPKIYEATMWIGASSPSGDNENITDVKILKPFADESLEIARKSLLGRLKYIPPKFSAKNINGTRAYKLARTGEEFSLKEQEMEVFSCEILSYRHPFLTFRISLSEGGYVRSYAQLFGKRLGYDVCLSELKRISEGKFRFENEKFLNICEILNLPRNKYLGDVADIMDGKSLKPSDFTTQKDGIYLLEYDKFLSIIEIKNDTISYCLNKVEKC
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: MTNB_XANCP
Sequence: MNATTAPLPYSAARLHELAQLLIGNIRELAQAGWTPATSSNFSHRLDEQHAAITVSGRDKGRLVEEDIMVVDFDGQPVGRPLRPSAETLLHTQLYRRFPEIGCVLHTHSPVQTIASRLYAGSGVIRLEGYELLKAFEGNTTHETAVDVPVFANTQDMQVLAAQVEALLDKQSMWGYLIEGHGLYAWGRNMAEARRHLEAFEFLLHCELELLKLRSPR
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: HIS8_CLOK5
Sequence: MIEKLFKQNLQKFVPYTVPKLDYEIKLDANESFLKLDDYMMGKILNKIKDVEFNRYPDAGAEKVCRAYSKYVGINRENIMAGNGSDELIQIIIAALVDKNENIMTVEPDFSMYGNYSEIGGGKALIFQLDEEFNLDVDKLIESANVEKVKVLFLSNPNNPTGKVLKREQIFKILNGCDCAVVIDEAYVEFHEESIVDSIYEYENLIVLRTCSKAMASAAIRLGFLITNSFMLNEIKKAKPPFNVSSVTQAIGEAVLEETEYIKKSLENIKNERSFLIDKLSAFKEIKLYPTCANFILIKFKDAEFVYKYLLENKIVVRNYKQGRLKDFLRITVGSREENEAVINNLSKILK
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: NMDE3_RAT
Sequence: MGGALGPALLLTSLLGAWARLGAGQGEQAVTVAVVFGSSGPLQTQARTRLTSQNFLDLPLEIQPLTVGVNNTNPSSILTQICGLLGAARVHGIVFEDNVDTEAVAQLLDFVSSQTHVPILSISGGSAVVLTPKEPGSAFLQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLEGVRAVADASYLSWRLLDVLTLELGPGGPRARTQRLLRQVDAPVLVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALGSTDAPPAAFPVGLISVVTESWRLSLRQKVRDGVAILALGAHSYRRQYGTLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWEGRDFSFSPGGYLVRPTMVVIALNRHRLWEMVGRWDHGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPNTVPCRRQSNHTFSSGDLTPYTKLCCKGFCIDILKKLAKVVKFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKPGGPSFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQLLGDGETQKLETVWLSGICQNEKNEVMSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRHSVPNSSQLDFLLAFSRGIYSCFNGVQSLPSPARPPSPDLTADSAQANVLKMLQAARDMVNTADVSSSLDRATRTIENWGNNRRVPAPTASGPRSSTPGPPGQPSPSGWGPPGGGRTPLARRAPQPPARPATCGPPLPDVSRPSCRHASDARWPVRVGHQGPHVSASERRALPERSLLPAHCHYSSFPRAERSGRPYLPLFPEPPEPDDLPLLGPEQLARREAMLRAAWARGPRPRHASLPSSVAEAFTRSNPLPARCTGHACACPCPQSRPSCRHLAQAQSLRLPSYPEACVEGVPAGVATWQPRQHVCLHAHTRLPFCWGTVCRHPPPCTSHSPWLIGTWEPPAHRVRTLGLGTGYRDSGVLEEVSREACGTQGFPRSCTWRRVSSLESEV
What is the function of this protein?
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.  Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:1350383, PubMed:8428958, PubMed:28126851).  Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable).  Plays a role in regulating the balance between excitatory and inhibitory activity of pyramidal neurons in the prefrontal cortex.  Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (By similarity).
What are the official names of this protein?
Glutamate receptor ionotropic, NMDA 2C, GluN2C, Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2C/GRIN2C subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: RL23_PICTO
Sequence: MDYIISPIVTEKTTLMMEKENKITFLVNRKATKEAIKNEVEARFNVKVAKVNMMIAKNGKKAIVTLAKDFSAEEVGGRMGIF
What is the function of this protein?
Binds to 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: TGL4_YEAST
Sequence: MSSKISDLTSTQNKPLLVTQQLIEKYYEQILGTSQNIIPILNPKNKFIRPSKDNSDVERVEEDAGKRLQTGKNKTTNKVNFNLDTGNEDKLDDDQETVTENENNDIEMVETDEGEDERQGSSLASKCKSFLYNVFVGNYERDILIDKVCSQKQHAMSFEEWCSAGARLDDLTGKTEWKQKLESPLYDYKLIKDLTSRMREERLNRNYAQLLYIIRTNWVRNLGNMGNVNLYRHSHVGTKYLIDEYMMESRLALESLMESDLDDSYLLGILQQTRRNIGRTALVLSGGGTFGLFHIGVLGTLFELDLLPRVISGSSAGAIVASILSVHHKEEIPVLLNHILDKEFNIFKDDKQKSESENLLIKISRFFKNGTWFDNKHLVNTMIEFLGDLTFREAYNRTGKILNITVSPASLFEQPRLLNNLTAPNVLIWSAVCASCSLPGIFPSSPLYEKDPKTGERKPWTGSSSVKFVDGSVDNDLPISRLSEMFNVDHIIACQVNIHVFPFLKLSLSCVGGEIEDEFSARLKQNLSSIYNFMANEAIHILEIGSEMGIAKNALTKLRSVLSQQYSGDITILPDMCMLFRIKELLSNPTKEFLLREITNGAKATWPKVSIIQNHCGQEFALDKAISYIKGRMIVTSSLKTPFQFADSVIGLIKAPEQTSDESKNPENSTLLTRTPTKGDNHISNVLDDNLLESESTNSLLLLRENASTYGRSPSGFRPRYSITSASLNPRHQRRKSDTISTSRRPAKSFSFSVASPTSRMLRQSSKINGHPPPILQKKTSMGRLMFPMDAKTYDPESHELIPHSASIETPAMVDKKLHFGRKSRYLRHMNKKWVSSSNILYTDSDKEDHPTLRLISNFDSDAMIHSDLAGNFRRHSIDGRPPSQATKSSPFRSRPSSSTQHKSTTSFTQ
What is the function of this protein?
Lipid particle-localized triacylglycerol (TAG) lipase.  The lipid droplet/particle is a lipid storage compartment which serves as a depot of energy and building blocks for membrane lipid biosynthesis.  Involved in the mobilization of the non-polar storage lipids triacylglycerols (TAGs) from lipid particles by hydrolysis of TAGs, releasing and supplying specific fatty acids to the appropriate metabolic pathways (PubMed:16135509, PubMed:16267052).  Also has steryl ester (SE) hydrolase and phospholipase A(2) (PLA(2)) activities, and catalyzes the acylation of lysophosphatidic acid (LPA) (PubMed:20332534).  Contributes to early bud formation in late G1 phase of the cell cycle upon phosphorylation and activation by cyclin-dependent kinase 1 (Cdk1/CDC28) (PubMed:19150427).
What are the official names of this protein?
Triacylglycerol lipase 4, Lipase 4.
What are the subcellular locations of this protein?
Lipid droplet. Note=Partially retained in the endoplasmic reticulum in cells lacking triacylglycerols.
Protein: FTCD_PIG
Sequence: MSQLVECVPNFSEGKNQEVIDAISRAVAQTPGCVLLDVDSGPSTNRTVYTFVGRPEDVVEGALNAARAAYQLIDMSRHHGEHPRMGALDVCPFIPVRGVTMDECVRCAQAFGQRLAEELGVPVYLYGEAARTAGRQSLPALRAGEYEALPEKLKQAEWAPDFGPSAFVPSWGATVAGARKFLLAFNINLLSTREQAHRIALDLREQGRGKDQPGRLKKVQAIGWYLDEKNLAQVSTNLLDFEVTGLHTVFEETCREAQELSLPVVGSQLVGLVPLKALLDAAAFYCEKENLFLLQDEHRIRLVVNRLGLDSLAPFKPKERIIEYLVPEAGPEQSLLHKPLRTFVREVGSRSAAPGAGSVAAATAAMGAALASMVGLMTYGRRQFEHLDATMRRLIPPFHAASAKLTSLVDADARAFEAYLKAMKLPKDTPEDKDRRAAALQEGLRQAVAVPLALAETVASLWPALQELALCGNLACRSDLQVAAKALETGVFGAYFNVLINLKDVTDDAFKAQVRQRISSLLQEAKTQAALVLDRLEARQA
What is the function of this protein?
Binds and promotes bundling of vimentin filaments originating from the Golgi.
What are the official names of this protein?
Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, FTCD.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the formiminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=More abundantly located around the mother centriole.
Protein: PROK1_RAT
Sequence: MRGAVQVFIMLLLATVSDCAVITGACERDVQCGAGTCCAISLWLRGLRLCTPLGREGEECHPGSHKIPFFRKRQHHTCPCSPSLLCSRFPDGRYRCSQDLKNVNF
What is the function of this protein?
Potently contracts gastrointestinal (GI) smooth muscle.  Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands.  Has little or no effect on a variety of other endothelial and non-endothelial cell types.  Induces proliferation and differentiation, but not migration, of enteric neural crest cells.  Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells.  Positively regulates PTGS2 expression and prostaglandin synthesis.  May play a role in placentation.  May play a role in normal and pathological testis angiogenesis (By similarity).
What are the official names of this protein?
Prokineticin-1, Endocrine-gland-derived vascular endothelial growth factor, EG-VEGF.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM3_BACMK
Sequence: MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLFVKEIEHALLTKEIDMAVHSMKDMPAVLPDGLTIGCTPKRVDPRDAFISKNGESFKDLAEGAILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKDEDYDAIILATAGLQRMGWDGEVITEHLDETLCVPAVGQGALAIECREDDTDLLQLLAHINDAVTERTVAAERVFLHKLEGGCQVPIAGYATLKENDAIELTALVGSMDGSVLLKEIVVGIDPKQVGLEAADRLIKQGAKELILAANKEQQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PG040_VACCW
Sequence: MIALLILSLTCSVSTYRLQGFTNAGIVAYKNIQDDNIVFSPFGYSFSMFMSLLPASGNTRIELLKTMDLRKRDLGPAFTELISGLAKLKTSKYTYTDLTYQSFVDNTVCIKPSYYQQYHRFGLYRLNFRRDAVNKINSIVERRSGMSNVVDSNMLDNNTLWAIINTIYFKGIWQYPFDITKTRNASFTNKYGTKTVPMMNVVTKLQGNTITIDDEEYDMVRLPYKDANISMYLAIGDNMTHFTDSITAAKLDYWSFQLGNKVYNLKLPKFSIENKRDIKSIAEMMAPSMFNPDNASFKHMTRDPLYIYKMFQNAKIDVDEQGTVAEASTIMVATARSSPEKLEFNTPFVFIIRHDITGFILFMGKVESP
What is the function of this protein?
Negatively regulates superinfection and syncytium formation in infected host cells.  Acts in concert with OPG185/A56 protein at the host cell membrane by interacting with and inhibiting the mature virion entry/fusion complex (EFC).  This mechanism ensures that new virions released from the cell cannot enter already infected cells.
What are the official names of this protein?
Superinfection exclusion protein, Protein K2, Serine proteinase inhibitor 3.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Orthopoxvirus OPG040 subfamily.
Protein: RIBB_BUCAI
Sequence: MNQTLLSKFGKPIERIKNAILALKSGQGVIILDDEERENEGDLVFACENMTVEQMALSIRYGSGIVCLCITESKRKQLNLPMMVKKNTSAYRTGFTVTIEASKGISTGVSAKDRLTTIKTAIADDAKPSDLNRPGHVFPLRAHKGGVLSRPGHTEAAIEIVSLAGFKPAGVICELTNKDGTMARTPEIIKFSENKKMQVLTIQDLIFYIKNINHL
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: TMN9_ARATH
Sequence: MEFYRSSRRLQILGSVILLLSIHVAHSFYLPGVAPQDFEKGDELKVKVNKLTSIKTQLPYSYYSLPFCRPKKIVDSTENLGEVLRGDRIENAPYSFKMREAQMCNVLGRVMLDAKSAKAFKEKIDDEYRVNMILDNLPLVVPIERIDPGQGSPSVVYQLGYHVGLKGQYEGSKEQKYFMHNHLAFTVRYHRDMQTDAARIVGFEVKPYSVKHEYEGQWSEKTRLTTCDPHTKRLVVSSATPQEVENKKEIIFTYDVDFQESEVKWASRWDAYLLMSDNQIHWFSIVNSLMIVLFLSGMVAMIMLRTLYRDISRYNELETQEEAQEETGWKLVHGDVFRPPANSDLLCVYVGTGVQCLGMVLVTMIFAMLGFLSPSNRGGLMTAMLLLWVFMGLFAGYASSRLYKMFKGTEWKRIAFRTAFLFPAVVSAIFFVLNALIWGQKSSGAVPFGTMFALIFLWFGISVPLVFVGAYLGFKKPPLDDPVKTNKIPRQIPEQAWYMNPIFSILIGGILPFGAVFIELFFILTSIWLNQFYYIFGFLFLVFVILMVTCAEITIVLCYFQLCSEDYLWWWRSYLTSGSSAVYLFLYAAFYFFTKLQITKLVSAMLYFGYMLIASYAFFVLTGTIGFYACLWFTRLIYSSVKID
What are the official names of this protein?
Transmembrane 9 superfamily member 9, Endomembrane protein 2, Transmembrane nine protein 9, AtTMN9.
What is the protein family that this protein belongs to?
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: BGAL_LATSK
Sequence: MQPNIQWLDTPAVFRVGQLPAHSDHRYYATLAEMAQQQSSFEQSLNGTWQFHYSVNAASRPKSFYELAFDAQDFEPITVPQHIELAGYEQLHYINTMYPWEGHYYRRPAFSTSDDKQHLGMFSEADYNPVGSYLHHFDLTPALRNQRVIIRFEGVEQAMYVWLNGQFIGYAEDSFTPSEFDLTPYLKETDNCLAVEVHKRSSAAFIEDQDFFRFFGIFRDVKLLAKPRTHLEDLWVIPEYDVVQQTGQVKLRLQFSGDENRVHLRIRDQHQIILTADLTSGAQVNDLYKMPELVQAWSNQTPNLYTLELEVVDQAGETIEISQQPFGFRKIEIKDKVMLLNGKRLVINGVNRHEWHPETGRTITAEDEAWDIACMQRNHINAVRTSHYPDRLSFYNGCDQAGIYMMAETNLESHGSWQKMGAVEPSWNVPGSYDEWEAATLDRARTNFETFKNHVSILFWSLGNESYAGSVLEKMNAYYKQQDPTRLVHYEGVFRAPEYKATISDVESRMYATPAEIKAYLDNAPQKPFILCEYMHDMGNSLGGMQSYIDLLSQYDMYQGGFIWDFIDQALLVTDPVTGQRELRYGGDFDDRPSDYEFSGDGLVFATRDEKPAMQEVRYYYGEHK
What are the official names of this protein?
Beta-galactosidase large subunit, Beta-gal large subunit, Lactase large subunit.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: FXL15_BOVIN
Sequence: MEPPMDPSGGEQEPGAVRLLDLPWEDVLLPHVLSRVPLRQLLWLQRVSRAFRALVQLHLARLRRFDAAQVGPQIPRAALAWLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALAGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRNLSLAVNANVGDTAVQELARNCPELQHLDLTGCLRVGSDGIRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGVDIDVEPPLHQALVLLQDMVGFAPFVNLQV
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway.  Required for dorsal/ventral pattern formation and bone mass maintenance.  Also mediates ubiquitination of SMURF2 and WWP2 (By similarity).
What are the official names of this protein?
F-box/LRR-repeat protein 15.
What is the protein family that this protein belongs to?
Belongs to the FBXL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCS_ORYSJ
Sequence: MVGFLRALTAASAVPAAAAVAAVALSTNSSSSSRLRLPSPASLPSLSSAYAAAPASGSARKPNAVPPMAAAAATADLSAAADKGAALPELMTEFMVDMKCDGCVTAVKNKFQTLEGIKNIEVDLNNQVVRVLGSLPVNTMLDTLHQTGRDARLIGQGNPNDFLVSAAVAEFKGPVIFGVVRLAQVNMELAIVEATFSGLSPGKHGWSINEFGDLTRGAESTGKVYNPSDYRSNKPLGDLGTLEAGEKGEAQFSASKEKLKVVDLIGRSIALYATEDRSDPGIAAAVIARSAGVGENYKKLCTCDGVTIWESS
What is the function of this protein?
Copper chaperone for superoxide dismutases (SODs).  Binds copper ions and delivers them specifically to SODs.  Is required for assistance in SODs disulfide bond formation and thereby activation of SODs (By similarity).
What are the official names of this protein?
Copper chaperone for superoxide dismutase, chloroplastic, Superoxide dismutase copper chaperone.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LYP1_YEAST
Sequence: MGRFSNIITSNKWDEKQNNIGEQSMQELPEDQIEHEMEAIDPSNKTTPYSIDEKQYNTKKKHGSLQGGAIADVNSITNSLTRLQVVSHETDINEDEEEAHYEDKHVKRALKQRHIGMIALGGTIGTGLFVGISTPLSNAGPVGSLIAYIFMGTIVYFVTQSLGEMATFIPVTSSITVFSKRFLSPAFGVSNGYMYWFNWAITYAVEVSVIGQVIEYWTDKVPLAAWIAIFWVIITLMNFFPVKVYGEFEFWVASVKVLAIMGYLIYALIIVCGGSHQGPIGFRYWRNPGAWGPGIISSDKSEGRFLGWVSSLINAAFTYQGTELVGITAGEAANPRKTVPRAINKVVFRIVLFYIMSLFFIGLLVPYNDSRLSASSAVIASSPFVISIQNAGTYALPDIFNAVVLITVVSAANSNVYVGSRVLYSLARTGNAPKQFGYVTRQGVPYLGVVCTAALGLLAFLVVNNNANTAFNWLINISTLAGLCAWLFISLAHIRFMQALKHRGISRDDLPFKAKLMPYGAYYAAFFVTVIIFIQGFQAFCPFKVSEFFTSYISLILLAVVFIGCQIYYKCRFIWKLEDIDIDSDRREIEAIIWEDDEPKNLWEKFWAAVA
What is the function of this protein?
High-affinity permease for lysine.
What are the official names of this protein?
Lysine-specific permease.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PDI1_CAEEL
Sequence: MSLSVSFIFLLVASIGAVVADSENVLVLTESNFEETINGNEFVLVKFYAPWCVHCKSLAPKYDEAADLLKEEGSDIKLAKVDATENQALASKFEVRGYPTILYFKSGKPTKYTGGRATAQIVDWVKKKSGPTVTTVESVEQLEELKGKTRVVVLGYFKDAKSDAATIYNEVADSVDDAFFAVAGSAEVAAAASLNEDGVALIRTDGDDSETSTIAEAEITNTIALKQWLHAYKLSAVTEFTHESAQEIVGGDLKKFHFLIIRKSDSSFDETIAKFTEVAKKFRAKIVFVLLDVDVEENARILEFLGVDAKNTPANRIVSLADQVEKFKPQEGEDFEAFTNSYLEGKSAQDLKAQDLPEDWNALPVKVLVASNFNEIALDETKTVFVKFYAPWCGHCKQLVPVWDELAEKYESNPNVVIAKLDATLNELADVKVNSFPTLKLWPAGSSTPVDYDGDRNLEKFEEFVNKYAGSASESETASQDHEEL
What are the official names of this protein?
Protein disulfide-isomerase 1, PDI 1, Prolyl 4-hydroxylase subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.