PharMolix/UniProtQA huggingface dataset:
Protein: NUOB_DESDA
Sequence: MGEVVTKSGGAVHTGGQPLEVSKDGLRFFPGAGAVIGPLNALVNWGRAGSIWPVTFGLACCAIEMMATGAAHHDLDRFGIIFRASPRQADCMVVAGTLSKKMAPVLRRVYDQMPEPRYVLAMGSCACSGGLFQSYAVTQGVDQVVPVDVYVPGCPPRPEALFDGFIRLQEIINKEQMRWSPWR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RLMN_AERS4
Sequence: MMSEIKTNLLDLDRDAMRAFFVELGEKPFRADQIMKWIYHFGCDDFDQMNNVNKVLRERLKAIAEIRAPEVSREQRSSDGTIKWALQVGGQEVETVYIPEEDRATLCVSSQVGCALACKFCSTAQQGFNRNLKVSEIIGQVWRAAKIVGGKRPITNVVMMGMGEPLLNLANVIPAMRLMMDDFGYGISKRRVTISTSGVVPALDILGDQIDVALAISLHAPNDKLRSEIMPINDKYNIEDFLAGVRRYLAKSNANGGRVTVEYVLLDHINDDMQHAHELAKVLKDTPSKINLIPFNPFPGNPYGKPSNSRIDRFSKVLMEYGFTVIVRKTRGDDIDAACGQLVGEVIDRTKRTMKNRMQQDGISVKMV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB1_GEOSL
Sequence: MLQNQTRKLRVLVVDDSSFMRMVIRSVLEKDPAIEVVGIAVDGMEGVEKALALKPDLITMDIEMPRLDGISALKQVMAKCPTRVLMVSTLTCEGAKATFDALDAGAIDYIPKNVTDSADAQRVFREELLRKVKGAASSIFGRPMTTSAPRAIIAPPRQVQPAPRPSQALAGKFHYVGIGASTGGPVALQEVLGRIPGNYPHGIVVAIHMPKAFTGPYAERLNSKCSLQIKEANDGDIIQPGVVLVAPGGRHMALARQGNSIVVRTLSTAECPQYIYIPSVDHMMTTLADATNGSALGVILTGMGSDGFKGMKHLKSKGGITIVQDEATSTIYGMPRACIEGGVADTVLPLTQIGSEIARLGG
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROR2_DROME
Sequence: MAAGQWVGVVERVLRGMVLKWGANLAVLGLCVFLFASATHANSLNAIEEPVTRRHHQRHHEREREENGYCAPYSGKVCKEYLTGQVWYSLEDPTGGWKNEQVTTALWDELISDLTGLCREAAEKMLCAYAFPNCHMEGGRAVKAPLCFEDCQATHLQFCYNDWVLIEEKKERNMFIKSRGHFRLPNCSSLPHYNASMRRPNCSYIGLTELKESEVSYDCRNGNGRFYMGTMNVSKSGIPCQRWDTQYPHKHFQPPLVFHQLLEGENYCRNAGGEEPHPWCYTVDESVRWQHCDIPMCPDYVDPNAVDLNTPIKMEKFFTPSMIFLLAGIGFVAIVTLHLMILLVYKLSKHKDYSQPAGAATAECSVSMRGGGDCGGNLNTSRETLGGNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVYVRSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKGDENDFIPIRWMPLESILYNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDNTPLSVYALMRRCWNRKPSERPGFAEINHCIQHSIAESECKAML
What is the function of this protein?
Tyrosine-protein kinase receptor that functions during early stages of neuronal development.
What are the official names of this protein?
Tyrosine-protein kinase transmembrane receptor Ror2, dRor2, Neurospecific receptor tyrosine kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MOAA_SALPB
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPGGVTNNGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVGENDAIRQIAVTTNGYRLARDAASWREAGLTGVNVSVDSLDARQFHAITGQDKFRQVMAGIDAAFDAGFEKVKVNTVLMRDVNHHQLDTFLAWIQPRPIQLRFIELMETGEGSDLFRKHHISGQVLRDELIKRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLFGDGGVSLRDLLQDDAQQYALEERISDALREKKQTHFLHQSNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: PNP_CORU7
Sequence: MKGRGTHAMSSKKNNLPKNVSVEMVDPDAGIWEATATIDNGDFGSRTLRFETGLLARQADGAVTAYLDEDTILLSTTTASRSPREGIDFFPLTVDVEERMYSAGRIPGSFFRREGRPGTDAILAARLIDRPLRPTFVKGLRNEVQVVITVMSIDPNEMYDVLAINGASASTQLSGLPVSSSVGGVRMALVVDEEHPEGQWVAFPTREQVSQSVFELVVAGRVTEPAKGGRGKKSQPNVAVMMVEAGATDNVVERIAEGAPAPTEAVVAEGIEAAKPFIATLCAAQDALRDAVDTESREFELFPPFDEDVYSAVEAECDADVAQIMTIADKQERDESLAENMQETVDALIEQFPERESEIRAAHNDLTRTIVRQRILEDGFRIDGRDHTSIRDLGIVVQLLPRAHGSALFERGETQILGVTTLDTLKMEQTIDSLGPETSKRYIHHYNFPPYSTGETGRVGSPKRREIGHGALAERALTPVLPSREEFPYTIRQVSEALGSNGSTSMGSVCASTLSLYNAGVPLKAPVAGIAMGLVSGLVDGKEKFVSLTDILGAEDAFGDMDFKVAGTSEYVTALQLDTKLDGLPSEVLASALGQARSARLEILQLMEDAIDAPDQMSELAPRITKISIPQNKIGEVIGPKGKTINQITEETGANISIEDDGTVFVSAVGGEAAEAAIEKINAIANPQQPKVGDRFLGTVVKTTAFGAFISLLPGRDGLLHISNIGGDRRIEKVEDELNVGDKIQVEIADIDNRGKISLVPVDED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFT1_ASHGO
Sequence: MCSTGEEILAKSTQGATFLMMGQLFGKLVTFVLHNVLVRFLSPRIFGITSFLDFLSSTVLFFSREAIRLATLRIKTGGDGGRGGEMSAELQTAVNFANIPMCIGAPLAVVLAVWQYSNLNSYFTQLPFFSWSIYLVLLSILAELASEPLYVVNQFMLNYRKRSQFEGAAVAASCLVNFAVIYWYENWVNGRGETVHDSYKQEGIAVLAFALGKVARAMTLLALYYVDYVRHLAHEKLFSLSLTKVRVPGSVYTAYFDSDVLQHFKKVYFQLCFKHLLTEGDKLIINSLCTVEEQGIYSLLSNYGSLITRMVFAPIEESLLLFLTRLLSDKTQQNLHICMRVLVNLVKFYLYLALVIVIFGPTNSSFLLKFLIGSKWSSTSVLETIRVYCFYLPFLSMNGILEAFFASVASGDEILRHSYLMMLLSGVFLLNCWVFLAHFNLSLEGLIFSNIINMTLRIIYCSNYIRGFYKRLFADSKQTSLSSSFAGLKKILLLCIVVAYVDWSIIGYVQNIRQLLVNILLSVTLVLAMAYNERKLLLEFIKKSKPVPVKEN
What is the function of this protein?
May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
What are the official names of this protein?
Oligosaccharide translocation protein RFT1.
What is the protein family that this protein belongs to?
Belongs to the RFT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y667_ARCFU
Sequence: MRCMRGGWGRGWKRRCYSTGKPGWMRYESERDEKLRMLERMRDELEAELEEIKREIERLRR
What are the official names of this protein?
Uncharacterized protein AF_0667.
Protein: TNNI1_RABIT
Sequence: PEVERKSKITASRKLLKSLMLAKAKECQQEHEAREAEKVRYLAERIPALQTRGLSLSALQDLCRQLHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ
What is the function of this protein?
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin I, slow skeletal muscle, Troponin I, slow-twitch isoform.
What is the protein family that this protein belongs to?
Belongs to the troponin I family.
Protein: TOLB_ORITB
Sequence: MINNLSVSMTKVLKIILTIIIILFNTLSILANTTTLSSIKITKGNCTQIPIAINFFSAKSNEEHDLSQNIVSIISNDLNISKIFAPISSDLFIETEQGVAHIPLFTAWSQINANILINGEITKIDSTDFKVTFVIWDVFSAKEITRKSFTFPSQLWRSTAHKIADQIYKHVTGSKGNFNTKIVYVSESNSSNRKIRRIAIMDQDGANHNYITNGKNHVITPVFSPKNNQILYVSYHNKIPTVRIHDLNSGNNKILASFNGITFSPRFSPDGNKILVSNSSTKNVTHIYEINLLTGKIKQLTKGQSINTSPSYSPDGSKIAFVSDRSGSTQIYIMNDQGGNIKRLTSQPGAYTTPAWSPTNNYIAFTKIEAGEFSIGVIKLDGSNKRIIATKYLVEGPSWAPDGKTIIFSRAYKATKSTSTKVKLYSVDYTGYNEREIQTPENASDPNWSNEYE
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: OCCP_AGRT4
Sequence: MPNPVRPAVQLKDIRKNFGNLEVLHGVSLSANEGEVISILGSSGSGKSTLLRCVNMLEVPNAGSVAIMGEEIALEHRAGRLARPKDLKQVNRLRERAAMVFQGFNLWSHQTILQNVMEAPVHVQGRDRKACRDEAEALLERVGIASKRDAYPSELSGGQQQRAAIARALAMRPDVMLFDEPTSALDPELVGEVLKVMRDLAAEGRTMLIVTHEMDFARDVSSRTVFLHQGVIAEEGPSSEMFAHPRTDRFRQFLRRDGGTSH
What is the function of this protein?
Component of the octopine active transport system probably consisting of four subunits: Q, M, P and T.
What are the official names of this protein?
Octopine permease ATP-binding protein P.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CYB6_ANTAG
Sequence: MGKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVASGFAMTFYYRPTVTEAFASVQYIMTEVNFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVILAVLTVSFGVTGYSLPWDQIGYWAVKIVTGVPEAIPLVGSSLVELLRGSVSVGQSTLTRFYSLHTFVLPLLTAVLMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HGD_CAUVC
Sequence: MDLRYQTGFGSYFETEAHPGALPVGRNSPQKVPFGLYAEQLSGSAFTAPRHENRRTWLYRLRPSAGHEAYQPYAQDKLVSAFPGPATPNRLRWSPLEIPAAPTDFVDGLVSLAGNADAATLGGIAAHVYLVNVSMKNRVFYNADGEMLIVPQMGELTLVTEMGVLKAGPGHIAVIPRGVRFRVEVEGPARGYVCENYGAAFRLPELGPIGANGLANPRDFEAPVAAFEDIDTPTQVIQKFQGALWAATWDHSPLDVVAWHGNLTPYRYDLSRFNTINTVSYDHPDPSIFTVLTSPSDTPGTANCDFVIFPPRWMVAEDTFRPPWFHRNVMSEFMGLIHGAYDAKAGGFVPGGASLHNCMSDHGPDVASHKKATEVVLAPHKIDGTMAFMFESRWVFRPTHLALESAALQSDYDACWTGFPKARLS
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: F16PC_BACFN
Sequence: MTAQSNITPESIVADLRYLQLLSRSFPTIAAASTEIINLEAILNLPKGTEHFLTDIHGEYEAFQHVLKNASGAVKRKVNEIFGHTLREIEKKELCTLIYYPEEKLQLIKATETDIDDWYLITLNQLVKVCQNVSSKYTRSKVRKSLPAEFSYIIQELLHESTIEPNKHAYINVIISTIISTRRADDFIIAMCNLIQRLTIDSLHIVGDIYDRGPGAHIIMDTLCDYHNFDIQWGNHDILWMGAASGNEACMANVIRLSMRYGNLGTLEDGYGINLLPLATFAMDTYADDPCTIFAPKTNFADSTYNEKTLRLITQMHKAITIIQFKLEANIINRRPEFGMGGRKLLEKIDFERGVFVYEGKEYPLRDTNFPTVDPADPYRLTDEEQELIEKIHYSFMNSEKLKKHMRCLFTYGGMYLVCNSNLLYHASVPLNEDGSFKHVNICGKEYWGKNLLDKIDQLIRTAYFDEDDEEEKRFAMDYIWYLWCGPDAPSFDKDKMATFERYFIADKSLHKETKGYYYALRNKEEICDRILEEFGVTGQHTHIINGHVPVKTIKGEQPMKAGGKLLVIDGGFSKAYQPETGIAGYTLVYHSHGLQLVQHDPFQSTQKAIEEGQDIKSTTFVIEFNSQRMMVKDTDKGKELVTQILDLKKLLVAYRIGLIKEKV
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: HAT1_YEAST
Sequence: MSANDFKPETWTSSANEALRVSIVGENAVQFSPLFTYPIYGDSEKIYGYKDLIIHLAFDSVTFKPYVNVKYSAKLGDDNIVDVEKKLLSFLPKDDVIVRDEAKWVDCFAEERKTHNLSDVFEKVSEYSLNGEEFVVYKSSLVDDFARRMHRRVQIFSLLFIEAANYIDETDPSWQIYWLLNKKTKELIGFVTTYKYWHYLGAKSFDEDIDKKFRAKISQFLIFPPYQNKGHGSCLYEAIIQSWLEDKSITEITVEDPNEAFDDLRDRNDIQRLRKLGYDAVFQKHSDLSDEFLESSRKSLKLEERQFNRLVEMLLLLNNSPSFELKVKNRLYIKNYDALDQTDPEKAREALQNSFILVKDDYRRIIESINKSQG
What is the function of this protein?
Catalytic component of the histone acetylase B (HAT-B) complex.  Acetylates 'Lys-12' of free histone H4 in the cytoplasm.  The complex is also found in the nucleus, however it is not certain that it modifies histone H4 when packaged in chromatin.  Histone H4 'Lys-12' acetylation is required for telomeric silencing.  Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.  Involved in DNA double-strand break repair.
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FLHF_BORBU
Sequence: MVQYFTEKGPTYNEVIEIIKKKYGKNARVMTYKTVPHGGILGLFSKDWVEVSGYVRYDIGNQQINVEDEKRKILQSIKREENSSIEDVLKEVKSLKTELAHKKENINHPTITKIEDILRENDFSENYIKDINEFIKREFSLSDLDDYERVREDVVLYIAKTIKCSGSIIDNLKKRVFILVGPTGVGKTTTIAKLAAIYGINGESKSLNIKIITIDNYRIGAKKQIQTYGDIMGIPVRAIESFKDLKDEITDSKDFDLILVDTIGKSPKDFMKLAEMKELLNACGRDAEFHLAVSSTTKTSDVKEIFHQFSPFNYKTVIFTKVDETTCVGNLISLIYEMKKVVSYVTDGQIVPHNISVAEPLTFIRRINGYRISDDAEFIKKIKSKSYY
What is the function of this protein?
Necessary for flagellar biosynthesis.  May be involved in translocation of the flagellum (By similarity).
What are the official names of this protein?
Flagellar biosynthesis protein FlhF, Flagella-associated GTP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HSLU_DESAH
Sequence: MSDLKPMEIVRELDRYIIGQKNAKKSVAIALRNRWRRRQVPDDLRDEIAPKNIILIGPTGVGKTEIARRLARLTDSPFYKVEASKFTEVGYVGRDVESMIRDLMELTVNTLKVRQQEEVQEKAAAMAEERILDLLLPESGGPEGATLTEPHLEVVSSSSSKSSTREKLRKMLNNGKLDSRFVDIDVTGKASPMIEIFSNTGMEEMGINMKDMLGNLLPKNTKRRKVKVAEAMKILTQDEAAHLVDMEKVTADAVEMVEQSGIIFLDEIDKIAGKGNSQGPEVSKEGVQRDLLPIVEGSSVPTKYGTVKTDHILFIASGAFHIAKPSDLIPELQGRFPIRVELTSLGKDEFVRILTEPKNALILQYIALLRTEGVELEFTEDAIDKIASIAVDVNERTENIGARRLHTIMEKLLEEILFHAPDVEEKKMVVDADFVDKQLMEIVKDEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_NEIM0
Sequence: MAKHEIEERGDGLIEKMVAVNRVTKVVKGGRIMAFSALTVVGDGDGRIGMGKGKSKEVPVAVQKAMDQARRSMIKVPLKNGTIHHEVIGRHGATKVFMQPAKEGSGVKAGGPMRLVFDAMGIHNISAKVHGSTNPYNIVRATLDGLSKLHTPADIAAKRGLTVEDILGVNHG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: NIKR_HALS3
Sequence: MSVVSVSMPEELLERLDDFADDHGYTGRSEVVREASRNLLGEFEDKKLEGRELMGVVTVVFDYETTTVEEKMMHLRHEHEGLVASNFHSHVGGHHCMELFVLEGSLESISTFVGKIRATKDTLTIDYSVLPVDEFGGLADVS
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: GLMS_RHILO
Sequence: MCGIVGIVGHSQVAPLIVDALKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKEEPLDGTIGIGHTRWATHGVPNETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSSQTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAIMFKGDEDLIVGARNGPPLAVGHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTSFMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGTAYLAGLIGKYWFERYARLPVDIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYCRKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTKAFTCQLSVLASLAVRAGVARGVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEGALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGKIILITDSKGAAQVSVKTMETIILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_SCHPO
Sequence: MAESAPRGFGRGGRGGRGRGRGRRGAKRDEEKEWVPVTKLGRLVKAGKIKSIEEIYLYSLPIKEYQIVDYFLPRLNDEVMKVVPVQKQTRAGQRTRFKAFVVIGDSDGHVGLGIKCAKEVATAIRGAIIMGKLSIMPIRRGYWGTALGDPHTVPVKVSGKCGSVTVRLVPAPRGAGLVAAPVTKRFLQLAGIEDCYTQSRGSTKTLGNFVKAAFAAASLTYGILTPNLWAERPFGQTPIEEYADILMQTEKKY
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  Plays a role in the assembly and function of the 40S ribosomal subunit.  Mutations in this protein affects the control of translational fidelity.  Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
What are the official names of this protein?
40S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: Y075_NPVOP
Sequence: MAGGLRGFVAELKKSTEFVAKVIFVKARLSDWLNSQVYPDERFSAKWRGVLKMFVDGQLDEESVYCLVNTIDPSKLLTVGQINYLARAFRNNRKMMSITQKFVDGYRLSDDDISELSNYLVAQVEEVYQL
What are the official names of this protein?
Uncharacterized 14.9 kDa protein.
Protein: CYAA_YERPE
Sequence: MYLYIETLKQRLDAINQLRVDRALAAMGPAFQKVYSLLPILLHCHHPQMPGYLDGNVPHGVCLFTPNEIQQDYLADVEARWGEPLAPSAGGELPITGVYSMGSTSSIGQCHTSDLDIWVCHQAWLDTEERNQLQQKCSLLEKWAASMGVEVSFFLVDENRFRHNASGSLGGEDCGSTQHILLLDEFYRSAVRLAGKRILWNMVPVKEEEHYDDYVLSLYAQGVLTPNEWLDLGGLSTLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNSQLLAMEIKQHLHAGEIVSFGLDAYCMMLDRVTRYLIQINDTTRLNLVRRCFYLKVCEKLSRTPASTGWRREVLSQLVSEWGWSNEKLAVLDNRANWKIERVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEEHLTFIHVPAGRANRPGWYLYNQAPSMDAIVSHQPLEYNRYLNKLVSWAYFNGLLTSKTHLHIKSANLCDTVKLQELVTDISHHFPLRLAAPTPKALYSPCEIRHLAIIVNLEHDPTTTFRNQVVHFDFRKLDVFSFGEQQQCLVGSIDLLYRNSWNEVRTLHFSGEQAVLEALKTILGKMHQDAAPPESVDVFCYSQHLRGLIRTRIQQLVSECIDLRLSSTRQEPGRFKAVRVSGQTWGLFFERLSVSVQKLENAVEFYGAISNNKLHGLSVQVETNQIHLPPVVDGFASEGIIQFFFEGTADEKGFNIYILDEANRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVQLDGRTQVIPFRSNTLSQLCANIAEKEASLPTKQCQLH
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_I80AA
Sequence: MKAKLLVLLCALSATDADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGKCSIAGWILGNPECESLVSKKSWSYIAETPNSENGTCYPGYFADYEELREQLSSVSSFERFEIFPKESSWPKHNVTRGVTASCSHKGKSSFYRNLLWLTEKNGSYPNLSKSYVNNKEKEVLVLWGVHHPSNIENQKTIYRKENAYVSVVSSHYNRRFTPEIAKRPKVRDQEGRINYYWTLLEPGDTIIFEANGNLIAPWYAFALSRGFGSGIITSNASIDECDAKCQTPQGAINSSLPFQNVHPVTIGECPKYVRSTKLRMVTGLRNIPSIQSRGLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAINGITNKVNSVIEKMNTQFTAVGKEFNKLEKRMENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVKNLYEKVKSQLKNNAKEIGNGCFEFYHKCNNECMESVKNGTYDYPKYSEESKLNREKIDGVKLESMGVYQILAIYSTVASSLVLLVSLGAISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: UB2L3_BOVIN
Sequence: MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
What is the function of this protein?
Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases.  Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN and ARIH1, that function like RING-HECT hybrids.  Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-11'-linked polyubiquitination.  Involved in the selective degradation of short-lived and abnormal proteins.  Down-regulated during the S-phase it is involved in progression through the cell cycle.  Regulates nuclear hormone receptors transcriptional activity.  May play a role in myelopoiesis.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 L3, E2 ubiquitin-conjugating enzyme L3, Ubiquitin carrier protein L3, Ubiquitin-protein ligase L3.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.