PharMolix/UniProtQA huggingface dataset:
Protein: NUOH_FRATF
Sequence: MLGYILWTSLYVLLIVIPLILVVAYYTYAERKVIGYMQDRIGPNRVGSFGLLQPIFDALKLFLKEIIVPTNSNRYLFFIAPILAFAPAYAAWAVIPFSKGVVLSDMNLGLLYILAMTSFSIYGIVIAGWASNSKYSLFGALRAGAQVISYELAMGFAIVGVVIAAGSMGITGIIEAQSGGIWHWYFIPLFPLFIVYFIAGIAETNRAPFDVVEGESEIVAGHHIEYTGSRFALFFLAEYANMILISILTSIMFLGGWNSPFQATALESIFGFVPGVVWLFAKTGIFMFMFLWVRATYPRYRYDQIMRLGWKIFIPLTFVWVVIVACMVRLGVGPWW
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGRP1_MOUSE
Sequence: MLFACALLALLGLATSCSFIVPRSEWRALPSECSSRLGHPVRYVVISHTAGSFCNSPDSCEQQARNVQHYHKNELGWCDVAYNFLIGEDGHVYEGRGWNIKGDHTGPIWNPMSIGITFMGNFMDRVPAKRALRAALNLLECGVSRGFLRSNYEVKGHRDVQSTLSPGDQLYQVIQSWEHYRE
What is the function of this protein?
Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems.  Acts as a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria and thus provides bactericidal activity (PubMed:9707603, PubMed:9660837, PubMed:12649138).  Forms an equimolar complex with heat shock protein HSPA1A and induces programmed cell death through apoptosis and necroptosis in tumor cell lines by activating the TNFR1 receptor on the target cell membrane (PubMed:14585845).  In addition, acts in complex with the Ca(2+)-binding protein S100A4 as a chemoattractant able to induce lymphocyte movement.  Mechanistically, this complex acts as a ligand of the chemotactic receptors CCR5 and CXCR3 which are present on the cells of the immune system.  Promotes also the activation of lymphocytes that become able to kill virus-infected cells as well as tumor cells by modulating the spectrum of their target-cell specificity.  Induction of cytotoxicity on monocyte surface requires interaction with TREM1 receptor (By similarity).
What are the official names of this protein?
Peptidoglycan recognition protein 1, Cytokine tag7, Peptidoglycan recognition protein short, PGRP-S.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Exists in both soluble and membrane-associated forms.
Protein: DPCHB_COLHI
Sequence: MNVADISQAPEAYRDVVWIADTCKLIMGIGWTANYVGMIRKSLKDQTYAMALLPLCCNFAWELTYAIMYAFTTSLEKYVHFSGLLLNCGVMYTAVKNAPREWEHAPLVQRNLRLIFVLAVAGFASAHVVLAKQVGPELGQAWSAYACQLLLSVGGLCQLLCRGHSRGASYFLWFSRFFGSLVLVPQDIIRYTYWKEAHEFMGSPMYIWFVTIFLILDGSYGLCLWYVRRFEQQNPAAGKLKK
What is the function of this protein?
Terpene cyclase; part of the gene cluster that mediates the biosynthesis of the diterpenoid pyrones higginsianins A and B (PubMed:32286350).  The first step of the pathway is the synthesis of the alpha-pyrone moiety by the polyketide synthase dpchA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Probable).  The alpha-pyrone is then combined with geranylgeranyl pyrophosphate (GGPP) formed by the GGPP synthase dpchD through the action of the prenyltransferase dpchC to yield a linear alpha-pyrone diterpenoid (Probable).  Subsequent steps in the diterpenoid pyrone biosynthetic pathway involve the decalin core formation, which is initiated by the epoxidation of the C10-C11 olefin by the FAD-dependent oxidoreductase dpchE, and is followed by a cyclization cascade catalyzed by the terpene cyclase dpchB (Probable).  The short chain dehydrogenase/reductase dpchG then oxidizes the 8S hydroxy group to a ketone and the short chain dehydrogenase/reductase dpchH reduces the ketone to the 8R hydroxy group to yield higginsianin B (PubMed:32286350).  Finally, the FAD-dependent oxidoreductase dpchF converts higginsianin B into higginsianin A (PubMed:32286350).
What are the official names of this protein?
Terpene cyclase dpchB, Diterpenoid pyrone biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the paxB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DRS5_PHYDS
Sequence: GLWSKIKEAAKTAGLMAMGFVNDMV
What is the function of this protein?
Antibacterial peptide with activity against Gram-positive bacteria S. aureus and E. faecalis, and Gram-negative bacteria P. aeruginosa and E. coli.
What are the official names of this protein?
Dermaseptin-DI5, DRS-DI5, Dermadistinctin-Q2, DD Q2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EAA1_BOVIN
Sequence: MTKSNGEEARLGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQPNETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLISQESEIEKSMDSETKM
What is the function of this protein?
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7723632).  Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (By similarity).  Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).
What are the official names of this protein?
Excitatory amino acid transporter 1, Sodium-dependent glutamate/aspartate transporter 1, GLAST-1, Solute carrier family 1 member 3.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MATK_WOLAR
Sequence: MEEFKGYLQKGGLKQQHFLYPLLFKEYIYALAYDQGLNASTFNEPDDISGYDKKYSSLLVKRLIKRLYQQNSLIRSVNKDKQTRFVGHNKNFYYQMVSEGFAIVLEIPLSLRLVSSLKEKKDIPKYQNLRSIHSIFSFLEDKFPHLHYISDILLPYPVHLEKLIQILQCWIHDGPTLHLLRLFFHDYHNWSNCITTKKSSYGFSKENPSLYRFLYNSYVVEAESIFVFLRKSSSYLRSTSFGPLLERTHFYGKMKHIGVTRCNDFQKPLGLFKDPMMHYVRYQSKVLIASRGTYLLLKKWKSYFMNLWQCHFDFWSEPSRIHINQFPKFSFYFLGYLSSIEMTPSSIKSQMLENYFLIDTVTPKFQTIIAISPIIGSLARARFCNLSGNPISKPVWTDLSDSEIIDRFGRLCRNLSHYYSGSSKKQSLYRIKYILRLSCARTLARKHKTTVRTFLQKLGSEFFEEFFMEEEKVLSLMLSRTSNPLHQLYREPIWFLDIIRLNDLVNHL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LPXK_ECOK1
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTGAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAIAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLAQLTSLASGH
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: EIF3A_CRYNJ
Sequence: MPPIYVKPENALKRSEELLALGTPQSQQQAFDNLVEVFQSKRFKQTPINVLEPIVTKFIDLCVVLSRKAHAKSGLLVFKSAAQTTNVGAIERVLNHFIAKAEARLAAAVEQAKKEVAALPDVPVVDDDLPLQPASLMLDCFVDSAGDRERIERRLIAPAQKFCWDSYDICLDIAKSNDRLEVIYQSIAHRAFHFCKIHQRKADFRRLCEQRLRKDLANAAKYSHQQHAINLSDPETLGRFLDTRFLQLETAVELELWQEAFRSIEDVHGLIAGRKGTKPSMMANYYEKLTQIFKAEGGKQTAVFHAAAWARYFQHAERAGIVNDKASGCVLLSALAVPLGEVEVKQRLVALLNLPKTPTREALVQDAAAKHLKRVPADIRQIYKILEVDFEPTTASKVLAPLITSLSPEYQPYLPALRDVVLSRLLQALAQVYDSVTLSHILDLVKPLDNTPWATDMSSLEKFLVTACRRGDIRASVDHVAQTITFVSTPPDANGLQTLAVCLYNTIQYLNPSRLAPVSRSDAFAAAIAQAEEERKAASHKRQIVIRRRELLEEAKLRREKEASTALAERLKIKAEEDARRAKEEAKQAEIDRVRKQIHETKQAEAKQLAASLAAQGALKVDISSIEDLDSSKLVAMQVEQLAKEKKELSERLRIVGKRVDHLERAMRKEERPLLAQDYERQKAEDRAAHDRANQIAREQAIEQQRAARELKQRLGRMLEDYEAVKERIESQMQEELKAAKEEARRKIEEEKAQLREKVIKRKREEKERKLKEAREAEERKRKEEEEAAQKAEEEARAAAALEAEAAAAEQRRAEREAQRQSDLERIRAQQEREEEALRRRQAEKAAATSGGSAYRPPARAGTTPPTASPAPSSGGPSWLARRKAMEAQSAGGAPVASSPKPVPSNSAAASAPASNGPESIAGEAEKPALTGSVWRRGMGARRGMPSTRGGA
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit homolog, eIF3 p110, Translation initiation factor eIF3, p110 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_PARL1
Sequence: MSDILEKIGAYKLDEIAAAKRARPLASVEEMARAAGSVRGFASALRARVDTGAYALIAEIKKASPSKGLIRADFDPPALARAYQAGGATCLSILTDGPSFQGAPDYLSDARAAVSLPVLRKDFMYDTYQVAEARAMGADAILIIMAAVSDAQAREIEEAAFGWKMDVLVEVHDEEELARAVELKSPLLGINNRNLKTFETTLATTERLAPLVPSGRLLVGESGIFAPDDLTRLSKVGVRTFLVGESLMRQTDVEAATRALLAPPA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: MSCL_BRUA4
Sequence: MLKEFKEFALKGNMVDLAIGVIIGGAFGGLVNSIVNDIIMPIIGLITGGIDFSNMFIQLAGEPRATLAAAREAGATIAYGNFVTLLINFLIIAWVLFLVVKGMNRMKKKEEAKPEPEAPREEVLLTEIRDLLAKQKA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH602_BRADU
Sequence: MSAKEVKFGVDARDRMLRGVDILHNAVKVTLGPKGRNVVLDKSFGAPRITKDGVTVAKEIELEDKFENMGAQMVREVASKSADAAGDGTTTATVLAAAIVREGAKSVAAGMNPMDLKRGIDMAVEAVVADLVKNSKKVTSNEEIAQVGTISANGDAEIGKFISDAMKKVGNEGVITVEEAKSLETELEVVEGMQFDRGYISPYFVTNADKMRVEMDDAYVLINEKKLSQLNELLPLLEAVVQSGKPLVIIAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMLQDIAILTGGQAISEDLGIKLENVTLNMLGRAKKVMIDKENTTIVSGAGKKADIEARVAQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKERKDRVDDAMHATRAAVEEGILPGGGVALLRASEHLKGIRTKNDDQKTGVEIVRKALSYPARQIAINAGEDGSVIVGKILEKDQYSYGYDSQTGEYGNLVSKGIIDPTKVVRVAIQNAASVAALLITTEAMVAEVPKKNTGAGGMPPGGGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1PF_HALVD
Sequence: MILTVTPNPAVDHTIHFDEPLQTGVVHRTDDAVFTAGGKGINVAKYASALDADVTASGFLGGHFGKFVRDRLDADGIASDFVTVDADTRLNTTVLAADGEYKLNHNGPQIRAADVDELVETAQANEPDTLLVGGSLPPGMSLSDVDRLARAGDWKIAVDMGGEYLAELDADYYVCKPNRSELAAATGRTVETEADAVEAAEELHARGFEYVLASLGADGALLVTDDEVLSAPALDVEVVDTVGAGDAVMSGFLAAREHGLSDADALRMGVLTASRVVGVAGTRVPDLEDVLTNETHVEVTTVRTR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.  Involved in the utilization of fructose as a sole carbon and energy source.
What are the official names of this protein?
1-phosphofructokinase, Fructose 1-phosphate kinase, Fru1PK.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: RL23_FRAT1
Sequence: MSSQEKLLKTVIRPHVSDKTYGLSDANSTIVFEVARFANKQDVKNAVEKLFEVKVESVNILNVKGKARRFGRVEGGTKAWKKAYVKLAEGHDINFVGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: PG100_VAR67
Sequence: MDHNQYLLTMFFADDDSFFKYLASQDDESSLSDILQITQYLDFLLLLLIQSKNKLEAVGHCYESLSEEYRQLTKFTDSQDFKKLFNKVPIVTDGRVKLNKGYLFDFVISLMRFKKESALATTAIDPVRYIDPRRDIAFSNVMDILKSNKAKNNYSLLSS
What is the function of this protein?
Late protein which is a part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions.  Plays a role in DNA packaging during immature virions (IV) formation.
What are the official names of this protein?
Virion assembly protein OPG100, Protein J1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG100 family.
Protein: RL30_METAR
Sequence: MYAIIRLKGSVNTRPEIKDTLRMLRLNQINHCVVVEENPTYKGMIQVVKDYVAFGVINADTLAMIMEHRGRLEGGDRLTNEYVAKNSSYKSIKEFAAAVAEGKAKLGDMPGLKPVFRMHPPRKGHKGLKRTYQQGGALGNYGEEIASLVEQMR
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PDRP_RHILO
Sequence: MNKPQSFFHLHLISDATGETLLAAGRAASAQYKDARAIEHIYPLIRTEKQVAKVFEDIEEEPGIILYTVVDQKLARGIDERCATMGLPCVSVLEPVLTVFQSYLGTPAGRRVGAQHVLDAEYFRRIDALNFTMDHDDGQLPANMDDADVVLIGISRTSKTPTSIYLANRGIKTANIPIVLGVPVPESLVSASKPLIVGLIATAERISHVRQNRILGNSSSYVPTDYVDRAAINEELAYARQICTRHGWPMIDVSRRSIEETAAAIVALRGKNR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: CNTLN_MOUSE
Sequence: MAARSPSSSPPPPPVRRSSRRSLRVGRGAEVHAVRSEASGLAGAAREVVADKSDLLWRGEEGSGGRRGSGRAGAAVAPVASAPAGSWWPEGLSSEEAKATRSQLLEEELSSLKEELALCQADKEFVWSLWRRLQATNPDLTQTVSLVVEREKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMSYQKLYNELHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEIEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSEMATTDVRARRCDCKTATTKVKFKAAKRKCSVGRHHTVLNHSIKVMSHVENLSKDGWEDVSEGSSDSETQTFQNLGTIIVETSQNISPIEDGRNQKEIDQTEGSCAQQRAMQTYSCEDIKAPQSISHNKNTKKMTFQKKSGSLQKSLHSALPARVNREKCKNLPAQKSSSSTISLRERIVSLQQQNSLLQNARRAAEASAKEYKEANEKLLHQQQVSDHRFQTSRQTIKKLTLDLAELRKEKEDLLKKVESSSDIMSLAEEVSRIMAPQIKVTTLGPSRSMDLEMKQLQCKLKNATNELTKQSSNVKSLRMELLAKDDHIKEMHERTSRMERDITMKRHLIEDLKFRQKVNSESNESFNEMLETLEKKVKSLTEECSNKKVSVDSLKQRLNVAVKEKSQYEQMYQKTKEELEKKDLKMSVLISKLNDTETAMAQIETAASEQLQGLALQSEQVLEGAQKKLLSANEKIEEFTVFVKALVNELQSDVHGTRHQIRELKKMQKSRHACKTSTHKAQTLAASILNISRSDLEEILDTEDELEIEKTKIDIENDKEWMLYIQKLLEGQLPFASYLLEAVLEKIKENKKLTEGYFTVMKDTK
What is the function of this protein?
Required for centrosome cohesion and recruitment of CEP68 to centrosomes.
What are the official names of this protein?
Centlein, Centrosomal protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Colocalizes with gamma-tubulin during interphase and mitosis. Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase. Localizes to the proximal ends of the centrioles. Levels are high at interphase centrosomes but are reduced on mitotic spindle poles.
Protein: CH60_STRP7
Sequence: MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGIKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYISEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYILITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGAGNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKLRIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQIAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVASLILTTEAVVANKPEPVAPAPAMDPSMMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIN_SALTY
Sequence: MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR
What is the function of this protein?
FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body.  This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
What are the official names of this protein?
Flagellar motor switch protein FliN.
What is the protein family that this protein belongs to?
Belongs to the FliN/MopA/SpaO family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Bacterial flagellum basal body.
Protein: MURG_ENTFA
Sequence: MKILVTGGGTGGHIYPALSFVEHVKKEAPATEFLYVGTENGLESQIVPKAKIPFKTIKIQGFKRSLSPQNFKTIYLFLTSINKAKKIIREFQPDVVIGTGGYVSGAVVYAAHQLKIPTIIHEQNSIPGMTNKFLSRYVDKIAICFPDVASFFPKEKTILTGNPRGQEVVTVEKSAILSEFGLDPAKKTVVLFGGSRGALKINQAFEQAFPLFEEREYQVLYASGERYYQELQESLKFSEKKLTNISVQPYIDKMVEVMANTDLMVGRAGATSIAEFTALGLPAILIPSPYVTNDHQTKNAQSLVKVGAVEMIPDAELTGARLVAAIDDILLNNEKRQQMATASKGEGIPDASDRLYQVVKTLV
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: THOC5_DANRE
Sequence: MSSDAVKKRKPKVIRSEAGTPETKRGRAESEQDVRVYNEEVELEGRDPQQDYTLYKETCAALAKLMSEIQELKTSGAKDGSAEIELRRKQSSIHFITLKKLNRLAHMRLKKGRDQTHEAKQRVDVLHLQLQNLLYEVMHLQKEIGKCLEFKSQHEEIELVSEDEFFQDAPAEISRPQVTREDHHQLTLARLDWELDQRKRLAEQYKTSLSSKEKIQKAIEQKREYLSSLQPGLHNIMQASLPVQEYLSMPFEHMQKQAEVARHLPPPLYVLFVQAGAYGQACDKNLTVSIRGDVDEAKALSRPPEDSQDDESDSDAEEEQQNTKRRRPTVGVQLDDKRKEMLRRHPLSLGIDLKCKDGSVLHLYFYYLMNLNILTVKTKVSTSVDLSGAISAGELLNSESLLNCLYASDHGNETPNPANRYQFDKVGITTFADYVSDLGHPYVWVQKLSGLQFSSDAAQSELSGSALSASHMEKSMKLLRGRLQSRLALHKQFSSLEHSIVPVSSECQHLFPAKVVSGLTRWTMMSHQEFTELSFVQHVLKAGLVSETDLFFKAVVERGTARLLAAVVVNPRYPEVTPLFSLSLLWKGERSGRTDDNLRAMESEVNVFRAELQGPRPGLQLLTNQIQRLCMCLDVYLETESQVSDGSEGPKEFPREKMCLRTARGPSRLKPFKYNHPQGFFSHR
What is the function of this protein?
May be involved in cell differentiation.
What are the official names of this protein?
THO complex subunit 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the THOC5 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm.
Protein: SRR1L_YEAST
Sequence: MDFKASGTKFKKTGKKVVPAKAFEEIVQTNRDVLKKSAFLSDLLENLQPHLNNIKKIRCVAIGNFKEDFPATYQFALLLEITDYIKSEDERDVVVSLYDPIFTKEEIQYLKSLGSKWLIEEEFSENDAIDYESVLYFLPHAPLDLTENILSSQRPHLWLANNMISHTDRYTKAKLCENYPNLSKLVHYLQTNAPPEVKKAHDVDGFATFIPKRKRKNRNNSSKLKVTPSDIDYDSIAPKFKSCQILTDFDEGKYLKEKPWINSFSDLTLHAIEY
What is the function of this protein?
Involved in microtubule stability and kinetochore function.  May be involved in protein N-terminus acetylation and/or proteasome biogenesis.
What are the official names of this protein?
SRR1-like protein BER1, Benomyl resistant protein 1.
What is the protein family that this protein belongs to?
Belongs to the SRR1 family.
Protein: KUP_KLEP7
Sequence: MSTDNKQSLPALTLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFTVSIKYITFVMRADNAGEGGILTLMSLAGRNTSARMTSVLVILGLIGGSFFYGEVVITPAISVMSAIEGLEIIAPQLDTWIVPISIIVLTLLFVIQKHGTGMVGKLFAPIMLIWFLLLAVLGARSIYANPEVLQALNPYWAVHFFLQYKTVSFIALGAVVLSITGVEALYADMGHFGKLPIRVAWFSVVLPSLVLNYFGQGALLLKHPEAIKNPFFLLAPEWALIPMLIIATLATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFINWLLYVSVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSATVARKNWHWNKLFVGLMLVAFLCIDIPLFSANLDKIVSGGWLPLSLGMVMFTVMTTWKSERFRLLRRMHEHGNSLEAMISSLEKSPPVRVPGTAVYMSRALNVIPFALLHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPSFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLIIGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.