PharMolix/UniProtQA huggingface dataset:
Protein: RBL_GLYEC
Sequence: SVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYGLEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVSYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGAPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIRQACK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS10_BORGP
Sequence: MIAKDKIRVRLFSFDVKILDQSAESIVKAVQKAKAQIKGPIPLPTKIKKYTVLRSPHVNKKSREQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MSRA_PSEE4
Sequence: MVLRSEILVNKNVLPTAEQALPGRETPMALPEFHYVFEGTPLLGPFFEGDIDFAIFALGCFWGAERRFWQREGVVSTVVGYAGGFTPNPTYEEVCSGLTGHTEVVLVVFDKNKVSYHDLLTMFWELHNPTQGMRQGNDVGTQYRSAIYCTSPQQLEEAKTSRDAFQAELSKAGFGEITTEIAQAPTVYFAEAYHQQYLAKNPDGYCGIGGTGVCLPPSLQGN
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: PAN1_ASPOR
Sequence: MYSSSNSFMGGANSARPGQPPFMQQPSYGQQTTQQQQQHQTGLAPQPNGYGSQLSGFGGSHLQPQPTGFSPGQLQSQMTGFPQLQQQPGFQTSAQPPQLTGYSIQSQAPQLQVPSSTGLPVRLAPQTSSEIADSFRGSAGAAPPPPPKTAGSKIPNIRLSFITAQDQAKFEQLFKSAVGDSQTMSGEKAKDLLLRSRLPGSDLSKIWVLSDTTKSGQLFFPEFALAMYLCNIRITGRGLPDALPEKIKNEVSSMVDIISFQVPDTQPEMAFPTNAPKFDAPLLENKSAPPAPQQPQPQQPTHSQLLTQLTAQPTGFHTQPTGIQSTQASFPGQSSSLVPQATAFPGQSQQQFLQTQPTGLMSNPQPTGYSGLRPPVPPMPTSLGPNLSPAQTGGVSGLVAQPTGVPGQWGFVNAPSSGLPNIEALKQQLMPQPGREGGFSAAGLSGNAHIPWAITKEEKKIYDDLFRAWDGFHKGFIGGDTAIEIMGQSGLDQKDLERIWTLADPHNRGRLNMDEFAVAMHLIYRKLNGYPVPNRLPPELVPPSTRNLNDSIGTIKSMLSQDAESRKASGAFLQPQKTGVSYLKDHSFRGGSGVSPGFGRKDATLFKNNDEAASGYRSSARRRVGNNGRTPSPATSQTSEEELSVGQLRKKIRETQIMLDAVDFQDENRAEEEDALDRRDRREVESLLDRIRRVQDDIDTHPDAAFRNLDNGAERRSLRRQLQSYEDQVPQVASDVRRVEREIAEAKLELFRLKDAKAHPNSASNIVGTGPGGAVTEADRIKARARARMQARAAELAGRPTPSSQEDDGAAARRVEAESAKVKADREKNDAMTRDVEDSVKDFARSLEDTLKDASENSTREHERRRWEDALGVEDVIRDFIYDLKRNSRTAYVRKEEASRSMHEEHERSRYDEAPATRPSPPPSTGSTGSLPGSTHEDRVAAARERAQKRIAERMAAAGLKPHNNTAETLLQRQEREKKEREDRLKQAEEEDTRREQERQRRLAEEQGGSMAQPAKPASKKPPPAPPSRRGRTDSAGQAEAKRAAEESAIVEQAAREQTIREEEEAQQERKRLEDDARKREEEFQREKEAQEARLRALQEQVQQGKIKKQEAKRRKEEADRLAKEQEAKLTVQRAELEMAKERERQLQLELEALDEESSSDEEGPENITPQHSTPGQSQILPEVDIAAPVAPSALVPPVPGPEPDRPTSATSSPTSDRTGLAHLPLETESKNPYFKKISLPAESQVATPQPISKAPVTSPKADVQSTNPFHRLAQQQENAKPAFTAAGPIERVSRARPEVDDDWSAAGSDFDSSDDDERPGGGSAKQLASILFGTMAPPRPLSAMDDKSPSKPSTPAPDTPVAASTAPEADGTLSIPSASIPPPPPPVVAQVPSIALSSGPPDAPPPPPPPPVPHMAPSAPPPGIPPPPAPPAAPAGAPNRSALLASIQAGKGLRKVQTNDRSLSSVAGRVLD
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein pan1.
What is the protein family that this protein belongs to?
Belongs to the PAN1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: LEXA_MOOTA
Sequence: MQPDLSPQLAMVLNYIRHFIDINGYPPSIRDICKATGLRSSSTVYNYLNKLEEKGYIRRDPSRSRAIEILTPYPALTRAKNMVSVPLLGKITAGQPILAFENIEDVFPLPADLAGAENAFMLHVSGDSMIEAGILDGDYLIVRPQDTAENGDIVVALLEDEATVKYFYRYPDHIELVPANSSMQPLIVHKVTILGKVVGLYRHFS
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: GATA_BIFLS
Sequence: MSNETATLVKLSAAEQAAAIKKGDVTSRELVEAHLKVIEAAEPSIKAFLKVSGDVALEQADAFDAKSAEDKAALPELAGVPIAIKDMIVTKGIETTAASKILEGWVPPYDATVIEKLKAAGMPILGKTNLDEFAQGSSTEHSAYQTTHNPWDTERVPGGSGGGSASAVAAFEAPIALGTDTGGSIRQPGALTGTVGVKPTYGGVSRFGAIAMASSLDQIGPVSRTVLDSALLQEIIGGHDKRDSTSIPEGPRPMVAAAREGAKRDLKGMKVGLIKELGGEGFQPGVEARFGEAVDKLKDMGAEVVEVSCPHIGYSLGAYYIIMPSEVSSNLARYDGMRYGLRVMPPAGVPQTAANMMAYTREAGFGDEVKRRIILGTYALSAGYYDAWYGSAQKVRTLIIEDFKKAFEQVDVLISPTSPSTAFKFGEKMDDPLAMYVNDIATIPANLAGMPAMSIPAGLSDDGLPVGFQFIAPQQRDEVMYKPAAALEAALEDGWNGPIWNDLKTPWLDGLGK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RL22_POLAQ
Sequence: MEVKAIHKSARISAQKTRLVADQIRGLPIARALNILNFSPKKAAFIVKKVVESAMANAEHNKGADIDELKVSTIIVDKGTSLKRFTARAKGRGNQIEKQTCHITVTLSN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PEPX_STRR6
Sequence: MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRFFFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDVFRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLATFSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKASDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDYFLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVKADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGGYPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYLLNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSIDFRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQAIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSSTNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKGYLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNTDYHLTVDLAQSMLTLPC
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDHR1_XENLA
Sequence: MKHEWNLCPSIFFSIFHICLSVQTNYGPYFFDNGPGSTNGNMALLSLSEDTPVGAYIYALNGSDPDGDPVTFGLTFEPGSKRYFAVDPDNGNVTLIEELDREKQDEIEVIVSISDGINKVSEKVRVLVTDANDESPGFLNTPYIVTVPEDTPPGSSIFKIEAVDKDTGSGGSITYIIQEMHGSKFTIDRHSGVLRIKAGVSLDFEKSRTHFVSVLAKDGGGKLRGKNQVFTSTTTVTINVEDVQDSPPVFVGTPYYGYVYEDTTMGSEVLTVKAYDGDRGNPNTIYYSIVNGSDGAFTINNATGGITVIKTPDELKKEVYELKIQVSEITPEGDKVAHAFTVATVRVVDLNNHPPTFYGENGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAGIDYEKFHLFTFKLLAIEVNTPEKFSSTADITIHLLDINDNVPRFSSEYYIARIPENSPGGSNVVAATATDLDSGLWGEIKYSIYGPGSDPFLIHPSTGIIYTQPWASLDAEVTSKYNFYVKAEDTEGKYSLAEVFVTVLDINDHSPEFSENIQEKTLIIGTPVKIEATDHDAEEPNNIVDYSIMQADPSNVFDIDQSTGEIKLKSYIRSLDIIQNITRNKDCKWSVVVQAKDRGSPSFSTTAVVKIDVTEETLLHKGPMAAFLMQSKDNPMKALGVLAGVMAIMVVITIFISTAMFWRNKKSNRVMPLRRIIKRRKNDHPPRTARTEWLKFKKSNNSADKFTIQEMESGPKNENRNNNYQGIPVPPRAPCPPPPPRLMPKVSKTERSLPTVSGSLTPKIIDQQMNERVPSASAALVSELKQMLEKKNAGSSMSFY
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.
What are the official names of this protein?
Cadherin-related family member 1, Photoreceptor cadherin, prCAD, Protocadherin-21.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: BACE2_MOUSE
Sequence: MGALLRALLLLVLAQWLLSAVPALAPAPFTLPLQVAGATNHRASAVPGLGTPELPRADGLALALEPVRATANFLAMVDNLQGDSGRGYYLEMLIGTPPQKVQILVDTGSSNFAVAGAPHSYIDTYFDSESSSTYHSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNSSFLVNIATIFESENFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDIFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQNLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRDENASRSFRITILPQLYIQPMMGAGFNYECYRFGISSSTNALVIGATVMEGFYVVFDRAQRRVGFAVSPCAEIEGTTVSEISGPFSTEDIASNCVPAQALNEPILWIVSYALMSVCGAILLVLILLLLLPLHCRHAPRDPEVVNDESSLVRHRWK
What is the function of this protein?
Responsible for the proteolytic processing of the amyloid precursor protein (APP).  Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.  It has also been shown that it can cleave APP between residues 671 and 672.  Involved in the proteolytic shedding of PMEL at early stages of melanosome biogenesis.  Cleaves PMEL within the M-beta fragment to release the amyloidogenic PMEL luminal fragment containing M-alpha and a small portion of M-beta N-terminus.  This is a prerequisite step for subsequent processing and assembly of PMEL fibrils into amyloid sheets.  Responsible also for the proteolytic processing of CLTRN in pancreatic beta cells.
What are the official names of this protein?
Beta-secretase 2, Aspartyl protease 1, ASP1, Asp 1, Beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Golgi apparatus. Endoplasmic reticulum. Endosome. Cell surface. Note=Colocalized with CLTRN.
Protein: VF385_ASFK5
Sequence: MDEIINKYQAVEKLFKEIQEGLAAYDQYKTLISELLHYNNHIKQEYFNFLMIISPYLIRAHSGETLRNKVNNEIKRLILVENINTKISKTLVSVNFLLQKKLSADGMKTKNMWCTNNPMLQVRTAHNLFKQLCDTQSKTQWVQTLKYKECKYCHTDMVFNTTQFGLQCPNCGCIQELMGTIFDETHFYNHDGQKAKSGIFNPNRHYRFWIEHILGRNSEQELGTKQDPCGTKVLQQLKKIIKRDNKCIALLTVENIRKMLKEINRTDLNNCVSLILRKLTGVGPPQISESILLRGEYIFTEAIKIREKVCKKGRINRNYYPYYIYKIFDAILPPNDTTNRRILQYIHLQGNDTLANNDSEWESICMELPEIKWKPTDRTHCVHFF
What are the official names of this protein?
Zinc finger protein B385R, pB385R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B385R family.
Protein: NRDR_SYNP2
Sequence: MQCPYCQHTDSRVLESRSTGAGRSIRRRRECLSCKHRFTTYERIEFVPISVIKRNGQSEAFDRSKILRGMVRACEKTTVLPSTLEAIAEEIEAQLQQKPKRSITTAQIGDLVLHRLRQESEVAYVRFASVYRQFQGVDDFIETLSHLQDNAEQANLWIQTLNEDEESEDLTSPSVLTPSAN
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ISCS_RUTMC
Sequence: MSTPTYMDYSATTPVDERVAQKMMQYLTTDGNFGNPASNSHYYGWKADEAVKKARHQVADLVGADSKEIVWTSGATESDNLAIKGIAHFYHKKGNHIITLKTEHKAVLDTCRQLERENYEATYLDPMPNGLLDLNVLKKAIREDTILVSIMHVNNEIGVIQDIEAIGNLCRENKIFFHVDAAQSAGKVTIDLSKLPVDLMSFSAHKIYGPKGMGALYVRRKPRVRIEAQMHGGGHERGMRSGTLATHQIVGMGEAFAIAQAEMKEENSKIRQLRDRLLAGFVNMEEVVINGDMKNRIPGNLNISFNYVEGESLMMAVNDIAVSSGSACTSSSLEPSYVLRALGLSDELAHSSIRFTIGRYTTEAQVDKAINLVRTKVDKLRDLSPLWDMFKDGIDISKVEWTAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_METPE
Sequence: MSLMILGTSSHVGKSVTVAAICRIMIRQGISVAPFKSQNMSLNSYVTRDGAEIGIAQAMQAFAARVLPSALMNPVLLKPKGDSTSQVVLLGHPYKDVQIRDYYQETDHLLEIAVDAYHQLVEEYGAVIVEGAGGAAEVNLYDRDIANIRLAEHLRLPIVLVADIERGGVFAQVYGTIALLPEQIRPLVKGIIINKFRGDPTLFESGVKTLEDLTGVPVLGVIPYTRLDLPSEDSLSLQDKERQTGLVRIAVIRLPQIANFTDFELLERHAAVDYLLPGESLDGYDCIIIPGTKNTVNDLLALQASGTAAAIRDARGQGVPVIGICGGYQMLGKTVIDDGSEARKGTYEGLGLLDLVTTFEGYDKTTVQVQRTAAPVPPILDAMGTVSGYEIHMGTTVLKSGRTAFAGEGAVSDDGLVFGTYLHGLFMVPAAAEALLSYLYSQRGLTFTGIEEQNEDPYDLLADHFEAHLQMERLLTLCSDHTPETPV
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Probable cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: COX5C_SOLTU
Sequence: AGXXXAHXXYKGPSVVKELVIXXXLGLXAG
What is the function of this protein?
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
What are the official names of this protein?
Cytochrome c oxidase subunit 5C, Cytochrome c oxidase polypeptide Vc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5C family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: AAEA_ECODH
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQILFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: BIOF_ACIF5
Sequence: MHSEREESWRAELSALRAHDLWRELQVLQPAPERGPPTFVGTRGEPLLSFASNDYLGLSAESALRDAAIAEIQQSGVGAGAAPLLGGERPAHAVLANALARWLGVEAALLFGSGYLANLGVISTLVGRGDRVYADRLNHASLVDGVRLSGARLHRYRHGDMTHLAQWLERGGRGQAWIITDGVFSMDGDIAPLPELATLAQQYGAGIILDEAHAFGVLGTEGQGTAAHWNMDIHGVDVIMGTLGKAFGVYGAFVAGSQDVVDLLRNRARSFIYHTALPSALAAAALVALDLLRHGDARRERLTQHRQHLRAQVPDAPWLASETPIQGLLLGDARRALTVSAQLRRAGLYCPAVRPPTVPADSARLRITLSAAHSHDDIELLATTLREVL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: GOGA3_HUMAN
Sequence: MDGASAEQDGLQEDRSHSGPSSLPEAPLKPPGPLVPPDQQDKVQCAEVNRASTEGESPDGPGQGGLCQNGPTPPFPDPPSSLDPTTSPVGPDASPGVAGFHDNLRKSQGTSAEGSVRKEALQSLRLSLPMQETQLCSTDSPLPLEKEEQVRLQARKWLEEQLKQYRVKRQQERSSQPATKTRLFSTLDPELMLNPENLPRASTLAMTKEYSFLRTSVPRGPKVGSLGLPAHPREKKTSKSSKIRSLADYRTEDSNAGNSGGNVPAPDSTKGSLKQNRSSAASVVSEISLSPDTDDRLENTSLAGDSVSEVDGNDSDSSSYSSASTRGTYGILSKTVGTQDTPYMVNGQEIPADTLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSRRDSICSSVSLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKTRKEPKGEASSSNPATPIKIPDCPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQMEEHALTVHESLSSWTPLEPATASPVPPGGHAGPRGDPQRHSQSRASKEGPGE
What is the function of this protein?
Golgi auto-antigen; probably involved in maintaining Golgi structure.
What are the official names of this protein?
Golgin subfamily A member 3, Golgi complex-associated protein of 170 kDa, GCP170, Golgin-160.
Protein: TYSY_KLEP7
Sequence: MKQYLDLMQKVLTEGTPKNDRTGTGTISIFGHQMRFNLQEGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRSWPAPDGRHIDQITTVMNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMVAQQCDLQVGDFVWTGGDTHLYSNHLEQTNLQLSREPRPLPKLVIKRKPASIFDYRFEDFEIEGYDPHPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_PYRAR
Sequence: MALAARRKVRIRLYGTNPADVDQVAREIVDLAKKMGVQVRGPIPLPTRRLVVTVRRAPSGQGYHTYDHWEMRISKRLIDIEASERVLRRLMTIRVPDTVKIELQLI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: FEOB_LEPIN
Sequence: MGHSDSSKTFRILMAGNPNCGKSTLFNQLTGLRQKTGNYHGVTVEKAEGIFHHLDHSVKILDLPGAFSLGGSSEDKQITSRVLIGHEAGDRILFVMDASLAERSLQFLLQILELNVPVLVAVTMKDVLEKKRVQLRLDLLSNEFGILFQYVNPKNGEGIKELKDRIVSPKAFCLPIRSFPWDSERENFLNDLLNSLSTEHSNSLKFVLTNSLKELSGEILQKGLPGLSLFSETPSKLIREKFERFGKRFTYLEELTQKSIYIKKILSNAIVGDPIPNERVLSKADKILLHPFWGLVSFLGIMALVFQALFTWSEMPMDWIESCVRNVGTFVGDFLEEGPLRSLIQEGIIGGVGAVLVFIPQISLLFLFIGILEETGYIARASFVMDRFMGKFGLSGKSFIPLLSSAACAVPAIMGTRTIENKSDRLTTILVSPLITCSARYPVYVLVIGAIFPSKNILGIFNVQALTMFGLFLLGMIASMFAALVFKKTFFKSDSSYFLIELPAYNTPSIKSLALTVFKKLKAFLSTAGQIILFISILLWFLANYPRIDSSLYPNLTDAELKKIQIRESYAGHSGKFMEPVLKPIGFDWKMGIGIITSFAAREIMVSTLSIIYGVGGEESTDDLKEALLKDTDENGKPVWGLSNSVSLLLFFAFACQCMSTLAVVKKETNSIFWPLFLFTYMTILAYSTSFIVFQVWQLFS
What is the function of this protein?
Probable transporter of a GTP-driven Fe(2+) uptake system.
What are the official names of this protein?
Fe(2+) transporter FeoB, Ferrous iron transport protein B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELO_BACC3
Sequence: MTKNNEVGWNLDNSYATLPQSFYTEIPPTPVSSPELVKLNHSLAISLGFNPEELKKEAEIAIFAGNALPEGAHPLAQAYAGHQFGHFNMLGDGRALLIGEQITPSGKRFDIQLKGSGPTPYSRRGDGRAALGPMLREYIISEAMYALDIPTTRSLAVVTTGEPTYRETKLPGAILTRVASSHIRVGTFQYAAARGSIEDLQSLADYTIKRHYPEIEAHENRYTALLQEVIKKQASLIAKWQLVGFIHGVMNTDNITISGETIDYGPCAFMDNYDQGTVFSSIDTQGRYAYGNQPYMAAWDLARLAESLIPILHEDEEEALKIAQDEISKFSVQYEKQWFIGMKKKLGLFSNEEQDQSLIEQLLKMMEKYKADYTNTFRSLTLDTLENTPLFDSPEFKEWYKLWQSRLEKQEESKENAYEMMKNNNPSIIPRNHRVEEALEAAVTNGDYSVMEKLLEALANPYAYSTDQEEYCVPPAPTNRPYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: SRP19_HALS3
Sequence: MVENVIWPAYFDAALSRRDGRRVPMELAVEEPSIDEIATAVQQVGYDAVVERDVAYPRRHWDAAGRVLVKDADDAKNTLVQAVAAYVGALRD
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM21_CANAW
Sequence: MPDSEPLEPLNQESSSNTEQLKLSTTPNIPARPQTRPQKQTTTTTTVPTDQDSTTETSLEKPLDNPQDELDELAHEIEKVLSDPVIPPRPEHGSSTKSSETQTEHKEQDFEPAHPAIPQRPTNKKETIQSEVSDHKNGLESKFDLKVNEETPADSVSTDKDKVHIKPSIPTIPSRPQSRNLDSSEVDNTKPSTTASIPARPQRQSTSTQDEYKPQASNTPDIPTRPQTKTEKSVSSEELDKPGDEPSSKDQDNERYTDDSNASKSILETEKAVAQEEKKAKKSDVDNKPSEPTTSTDSSTEPAAPARGFRLPLHMQQGSGPISTSTPVAGSEAELNSLNNSNTFGDGEVTPGNSDTKATFKNDEDVENENRTDSSSFDDDMETISQDNEDGEQDRRNRQETATEENAQESEAPQFETTIIESGETEERDGDDTDSGELYSEQQQNKEKEKIVPATSTPKIPQRPPKKSSLSRATTNDSLTSLDSTSKPPKPVIPKRPTTEESLSNIEPTIPSRPATKKITSVGESQHEPIVPNRPDNKDLESSQRDTQASVKSKPPPPKPKKLSSKIAAFQQQLFNPANASSKEDVSSTGSKQPESGIRKRSTENSVLSRFGGKAIPLPGMFNPNQMPKPSISHGEETSDDREEKQESATANAPVRRTRGPRGKKLPKAVADAEVKTESRFAIESGKLWSIEFKKKIVEEKEITSTSVEDLEKPKILSENDEAGDEGKETAVENEVIDNPEIPVKDELQHDVVDVVGHPEKDVVTGLDDDDEDVPPEVNERFIKDEEISNVGVERTIASETTTEKHSTDEEEVEEEAVVDSVDIPIRRVAVNIVDSTEVQKDVEDEP
What is the function of this protein?
Involved in mitochondrial migration along actin filaments.
What are the official names of this protein?
Altered inheritance of mitochondria protein 21.
What is the protein family that this protein belongs to?
Belongs to the AIM21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Cortical actin patches.