PharMolix/UniProtQA huggingface dataset:
Protein: GYAR_PYRHO
Sequence: MKPKVFITREIPEVGIKMLEDEFEVEVWGDEKEIPREILLKKVKEVDALVTMLSERIDKEVFENAPKLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFNMRILYYSRTRKEEVERELNAEFKPLEDLLRESDFVVLAVPLTRETYHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEGWIAGAGLDVFEEEPYYNEELFKLDNVVLTPHIGSASFGAREGMAELVAKNLIAFKRGEIPPTLVNREVIKIRKPGFE
What are the official names of this protein?
Glyoxylate reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VMPA2_TITPA
Sequence: DDCIVVEYYIVTDSRFTQRFDSDQAVTDYVTVMFTGVQNLIETLNLDIKVRLLGVTPYHKESEPSFIDDSLLPGHETYVDARKIVRNMKFYFCNHNTGLAKSADIIILLITRKMGVLDPGDTDISEIAGASSISSVCQRCNNVGACVDNSDHNERADTVAHESVHLLGSPHDGEGPNGLGLPNSPGAANCPDSDGYIMGTRNEQNGKKFSECTKQCVKYLLSLPRASCVYENCSK
What is the function of this protein?
Acts as a metalloprotease.  Penetrates intact tissue and specifically cleaves the vesicle-associated membrane protein 2 (VAMP2) (part of the SNARE complex) involved in pancreatic secretion, thus disrupting the normal vesicular traffic (By similarity).
What are the official names of this protein?
Venom metalloproteinase antarease-like TpachMP_B, VMPA.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEA_ECO5E
Sequence: MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRNLC_PERFH
Sequence: MSSISQKVVIGLNKAAANNNLQNLDRRGFKTRCVSSSKAASCLRASCSLQLDVKPVQEGRRSGNYQPSIWDFNYVQSLNTPYKEERYLTRHAELIVQVKPLLEKKMEPAQQLELIDDLNNLGLSYFFQDRIKQILSFIYDENQCFHSNINDQAEKRDLYFTALGFRLLRQHGFDVSQEVFDCFKNDNGSDFKASLSDNTKGLLQLYEASFLVREGEDTLEQARQFATKFLRRKLDEIDDNHLLSCIHHSLEIPLHWRIQRLEARWFLDAYATRHDMNPVILELAKLDFNIIQATHQEELKDVSRWWQNTRLAEKLPFVRDRLVESYFWAIALFEPHQYGYQRRVAAKIITLATSIDDVYDIYGTLDELQLFTDNFRRWDTESLGRLPYSMQLFYMVIHNFVSELAYEILKEKGFIVIPYLQRSWVDLAESFLKEANWYYSGYTPSLEEYIDNGSISIGAVAVLSQVYFTLANSIEKPKIESMYKYHHILRLSGLLVRLHDDLGTSLFEKKRGDVPKAVEICMKERNVTEEEAEEHVKYLIREAWKEMNTATTAAGCPFMDELNVAAANLGRAAQFVYLDGDGHGVQHSKIHQQMGGLMFEPYV
What is the function of this protein?
Monoterpene synthase (mono-TPS) involved in the biosynthesis of monoterpenes natural products (PubMed:17187833).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) into geraniol (PubMed:17187833).
What are the official names of this protein?
Geraniol synthase, chloroplastic, PcTps-C.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: URK_BACCQ
Sequence: MGTNKPVVIGIAGGSGSGKTSVTKAIFDHFKGHSILILEQDYYYKDQSHLPMEERLKTNYDHPLAFDNDLLIEHLQQLLAYKQVEKPVYDYTLHTRSDEIIPVEPKDVIILEGILILEDPRLCELMDIKLFVDTDADLRILRRMQRDIKERGRTMDSVIDQYVNVVRPMHNQFIEPSKKFADIIIPEGGQNHVAIDIMVTKIATILEQKVNL
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCDH_RHIME
Sequence: MTTITKAACIGGGVIGGAWAARFALAGIDVNIFDPHPEAERIIGEVMANAERAYGMLTMAPLPPRGKFTFCRSIQEAVEGVDWIQESVPERLPLKRGVINEIDAAARPDALIGSSTSGLLPSDLQAEMKHPERMFVAHPYNPVYLLPLVELVGGRKTSPETIRRAEEAVAEIGMKGVVIAKEIEAFVGDRLLEALWREALWLIQDDICDTETLDDVMRYSFGMRWAQMGLFETYRIAGGEAGMRHFLAQFGPCLKWPWTKFTDVVDLDDALVEKIGAQSDAQAAGRSIRELERIRDENLVGIMHALKAGDGGKGWGAGKLLADFEKRLWEKGGSPSKSLDASGPLRLVDTKVNAAWVDYNGHMTEHRYLQLFGDTSDALLKVIGVDFAYVEAGHSYYTVETHIRHLGEAKLGQALYTTLQLLSSDEKRIHFFTRIHDAASGDVIATAEQMMLHVDAKAGKSVPAPAEVMAKLKPIAEGHAKLDAPDGAGRHVGQKR
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
What are the official names of this protein?
L-carnitine dehydrogenase, CDH, L-CDH.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLK_ECO27
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVIRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEGIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDITERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASGFRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFS2_SCHPO
Sequence: MDSADIRSAKAALEKAIQGKNIETIINIMTRLKNEVVATEELLKETRLGLVVGKLRSHPNEKVGEQAREIVKKWKADVSKGRPLKTTTTTSSTPSKHADVGSQAQKQVQKQSSSGQRTFKSDNVNVNVTDDKIRNNCIGLMYNALVIDSDESSSLIIAKAKEIDAQVLARAAGKTGSEYRNRMRSLYMNLKDKNNPKLRASVLRNEITPQRLSTMTSAELASEDRRKEDAKLEQENLFHAQGAKPQKAVTDLFTCGKCKQKKVSYYQMQTRSADEPMTTFCECTVCGNRWKFS
What is the function of this protein?
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity).
What are the official names of this protein?
Transcription elongation factor S-II, TFIIS.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPF_DESHD
Sequence: MEIVKMHGLGNDFVFIDHFQGAPAELPDYPELARKLCHRQFGVGGDGLIMVLPSDKADARMRILNSDGSEPEMCGNGIRCFARYIYDQGYVSQNPLQVETLAGILTLQLSITGDQVTGVRVDMGEPILKSEQVPVLIQGDPVVGARLDVDGQEFEFTAVSMGNPHCVLFVEDYETLDFERIGPAIEKHPLFPRKTNVEFIIVNSPRELTMKVWERGAGPTLACGTGACASVVAAVLNGRTERKVTVHLPGGDLLIEWGEDNRVYMTGPAAYVFKGVLLEDALS
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDXN_BRADU
Sequence: MPFKIIASQCTSCSACEPLCPNVAISEKGGNFVIEAAKCSECVGHFDEPQCAAACPVDNTCVVDRALPRYQAPV
What are the official names of this protein?
Ferredoxin-like protein in nif region.
Protein: B3GT1_PANPA
Sequence: MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVARKNFTFGNIRTRPINPHSFEFLINEPNKCEKNIPFLVILISTTHKEFDARQAIRETWGDENNFKGIKIATLFLLGKNADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCSKAKYVMKTDSDIFVNMDNLIYKLLKPSTKPRRRYFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTGYIFSADVAELIYKTSLHTRLLHLEDVYVGLCLRKLGIHPFQNSGFNHWKMAYSLCRYRRVITVHQISPEEMHRIWNDMSSKKHLRC
What is the function of this protein?
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue.  Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins.
What are the official names of this protein?
Beta-1,3-galactosyltransferase 1, Beta-1,3-GalTase 1, Beta3Gal-T1, Beta3GalT1, UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: MUKB_SALNS
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLSLAELKDKLDEMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRLTLEAIRVTQSDRDLFKHLISEATDYVAADYMRHANERRVHLDQALAFRRELYTSRKQLAAEQYKHVDMARELGEHNGAEGSLEADYQAASDHLNLVQTALRQQEKIERYEADLEELQIRLEEQNEVVAEAAEMQDENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAISALARAKELCHLPDLTPESAAEWLDTFQAKEQEATEKLLSLEQKMSVAQTAHSQFEQAYQLVAAINGPLARSEAWDVARELLRDGVNQRHLAEQVQPLRMRLSELEQRLREQQEAERLLAEFCKRQGKNFDIDELEALHQELEARIASLSESVSSASEQRMALRQEQEQLQSRIQHLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQEVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGAEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQIAEQLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPSLPIFGRAARENRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLSVAFEDDPEAEIRRLNGRRVELERALATHESDNQQQRLQFEQAKEGVSALNRLLPRLNLLADETLADRVDEIQERLDEAQEAARFVQQYGNQLAKLEPVVSVLQSDPEQFEQLKEDYAWSQQMQRDARQQAFALAEVVERRAHFSYSDSAEMLSGNSDLNEKLRQRLEQAEAERTRAREALRSHAAQLSQYSQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARQRRDELHAQLSNNRSRRNQLEKALTFCEAEMENLTRKLRKLERDYHEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQSVSFGQVNSVRLNVNVRETHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDEARRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTQTEDTPSEAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: MNMG_METPB
Sequence: MHAESTRYDVIVVGGGHAGVEAAAAAARVGARTALVTHRAETIGTMSCNPAIGGLGKGHLVREVDALDGLMARVADAAGIQFRLLNRRKGPAVRGPRTQADRALYARAMQAAVAETPGLTVIEGEADDLIVEAGRVAGAMLADGRRLAAGAVVITTGTFLRGLIHIGERQIPAGRVGEEPALGLARTLDRHGFRLGRLKTGTPPRLDGRTIDWTALEMQHADADPVPFSTLTERITTPQIACGITRTTQRVHDLIRENLHRSPMYSGGISSRGPRYCPSIEDKVVRFGDREGHQIFLEPEGLDDPTVYPNGISTALPEVVQAGIIAAIPGLERTRILRPGYAIEYDYVDPRELDATLQTKRLPGLFLAGQINGTTGYEEAAGQGLVAGLNAARLAGASELAVFDRAESYLGVMIDDLVTHGVSEPYRMFTSRSEYRLSLRVDNADERLTPRGAALGCVGSIRAAHFAASQGALSEARTRLDTLSLTPNEAAAHGLALNRDGLRRTAFQLLSYPEIGWDRLAAIWPDLAAVPPRIAERLQTDATYAVYLDRQQADITAFRRDEAVRLPASLDYGTIAGLSNEMRVKLDGVRPTTLGQAARIEGVTPAALTLLAAHARRGRTQATA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG189_VACCW
Sequence: MDFFKKEILDWSIYLSLHYIARVFSNFSTSHIIQDYNLVRTYEKVDKTIVDFLSRLPNLFHILEYGENILHIYSMDDANTNIIIFFLDRVLNINKNGSFIHNLRLSSSINIKEYVYQLVNNDHPDNRIRLMLENGRRTRHFLSYISDTVNIYICILINHGFYIDAEDSYGCTLLHRCIYHYKKSESESYNELIKILLNNGSDVDKKDTYGNTPFILLCKHDINNVELFEICLENANIDSVDFNRYTPLHYVSCRNKYDFVKLLISKGANVNARNRFGTTPFYCGIIHGISLIKLYLESDTELEIDNEHIVRHLIIFDAVESLDYLLSRGVIDINYRTIYNETSIYDAVSYNAYNTLVYLLNRNGDFETITTSGCTCISEAVANNNKIIMEVLLSKRPSLKIMIQSMIAITKHKQHNADLLKMCIKYTACMTDYDTLIDVQSLQQYKWYILKCFDEIDIMKRCYIKNKTVFQLVFCIKDINTLMRYGKHPSFVKCTSLDVYGSRVRNIIASIRYRQRLISLLSKKLDPGDKWSCFPNEIKYKILENFNDNELSTYLKIL
What is the function of this protein?
Contributes to viral release without involving rearrangement of host actin.
What are the official names of this protein?
Ankyrin repeat protein OPG189.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG189 protein family.
Protein: ALLB_BACSU
Sequence: MAYDMVIKGAKAVTPDGVIEADIVVQNGVIAEIGSDIEASGTEIIQADGKYVFPGVIDCHVHFNEPGREDWEGFETGSQMMAAGGCTTYFDMPLNCIPSTVTAEHLLAKAELGRQKSAVDFALWGGLVPGHIEDIRPMAEAGAIGFKAFLSKSGTDEFRSVDERTLLKGMAEIAAAGKILALHAESDAITSYLQMVLANKGKVDADAYAASRPEEAEVEAVYRTIQYAKVTGCPVHFVHISTAKAVRLIREAKQEGLDVSVETCPHYVLFSHDDLRQRGSVAKCAPPLRSRQSKETLIETLIAGDIDMVSSDHSPCRPSLKREDNMFLSWGGISGGQFTLLGMLELALEHQIPFETIAEWTAAAPAKRFGLQKKGRLEAGCDADFVLVSMEPYTVTRESMFAKHKKSIYEGHTFPCSISATYSKGRCVYNDGEKVTEIDGALVVPS
What is the function of this protein?
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
What are the official names of this protein?
Allantoinase, Allantoin-utilizing enzyme.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
Protein: UREF_BRASB
Sequence: MTASERPHVSAAMTELDHPALYRLMTWLSPAFPVGGFAYSSGIEWAVEAGDVDDAASLRGWLSTMLTDGSGFCDAVFLVHAHRAMELGDIDRLREVAELAAAFVPSRERQLETTAQGRAFIEIARSAWNSPGLDDAVSQCEAMVYPVAVGVVGAAHGIQSSLLLHAYLHAVTSNWISAGSRLIPLGQTDSQRVLAALEPVVTATAVRAISASLDDIGSATFRADLASLRHETQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNN2_RAT
Sequence: MSSCRYNGGVMRPLSNLSSSRRNLHEMDSEAQPLQPPASVVGGGGGASSPSAAAAASSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFIETQMENYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
What is the function of this protein?
Forms a voltage-independent potassium channel activated by intracellular calcium (PubMed:8781233, PubMed:20562108).  Activation is followed by membrane hyperpolarization.  Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization.
What are the official names of this protein?
Small conductance calcium-activated potassium channel protein 2, SK2, SKCa 2, SKCa2, KCa2.2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CIDA_BACC3
Sequence: MKWWKLSGQILLLFCFAWTGEWIAKQAHLPVPGSIIGIFLLLISLKFNLVKKEWIQDGADFLLKELILFFIPSAVAVIRYKDTLSQYGIDLILIIMISTLCVTLVTGLLTELLLKRKGSVQ
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THSB_SULAC
Sequence: MSATATVATTPEGIPVIILKEGSSRTYGKEALRINIAAVKAVEEALKTTYGPRGMDKMLVDSLGDITITNDGATILDKMDLQHPAAKLLVQIAKGQDEETADGTKTAVIFSGELVKKAEELLYKEIHPTIIVSGYKKAEEMAIKTIEEISTKVSVNDTEILRKVALTSLSSKAVAGAREHLADIVVKAITQVAELRGDKWYVDLDNVQIVKKHGGSINDTQIVYGIIVDKEVVHPGMPKRVENAKIALLDASLEVEKPELDAEIRINDPTQMKKFLDEEENILKEKVDKIAQTGANVVICQKGIDEVAQHYLAKKGILAVRRAKKSDLEKLARATGGRVVSNIDELTSQDLGYATLVEERKIGEDKMVFIEGAKNPKAVSILIRGGLERVVDETERALRDALGTVADVVRDGRAIAGGGAVETEIAKRLRKYAPQVGGKEQLAIEAYANALESLVMILIENGGFDPIELLVKLRSAHENETNKWHGINVYTGQIQDMWSLGVIEPAVVKMNAIKAATEASTLILRIDDLISAGKKSEGKTGEKKESEKGKEED
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit beta, Chaperonin subunit beta, Thermophilic factor 55 beta, TF55-beta, Thermosome subunit 2.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: TRMN6_ECOL6
Sequence: MSQSTSVFRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHTADILQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_SHIF8
Sequence: MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQASKVEVAGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWVSTPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKAVLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAVTILENCGRKFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGDG_SPIOL
Sequence: MSHPSTVTSEPSNLLDFVPKLGNFVLNSSLHGNNSNGYSSFSSNSVHFGGLATQNRYKFVNSLSFSKEGSNLKRILSDFNRVIRLHCDRIPLGFSSIGLNSGESNGVSDNGHGVLEDVRVPVNAVEPESPKRVLILMSDTGGGHRASAEAIKAAFNEEFGDDYQVFVTDLWSEHTPWPFNQLPRSYNFLVKHGPLWKMMYYGTSPRVIHQSNFAATSVFIAREVARGLMKYQPDIIISVHPLMQHVPLRILRGRGLLEKIVFTTVVTDLSTCHPTWFHKLVTRCYCPSNEVAKRATKAGLQPSQIKVYGLPVRPSFVRSVRPKNELRKELGMDEHLPAVLLMGGGEGMGPIEATARALGNALYDANLGEPTGQLLVICGRNKKLAGKLSSIDWKIPVQVKGFVTKIEECMGACDCIITKAGPGTIAEAMIRGLPIILNDYIAGQEAGNVPYVIENGIGKYLKSPKEIAKTVSQWFGPKANELQIMSQNALKHARPDAVFKIVHDLDELVRQKIFVRQYSCAA
What is the function of this protein?
Involved in the synthesis of the major structural component of photosynthetic membranes.  The 1,2-diacylglycerol substrate preference is 18:2/18:2 > 18:0/18:1 > 18:1/18:1 > 18:1/16:0 > 16:0/18:2 > 18:3/18:3 > 16:0/18:1 > 16:0/16:0 > 18:0/18:0.
What are the official names of this protein?
Monogalactosyldiacylglycerol synthase, chloroplastic, SoMGD1, MGDG synthase type A.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane.
Protein: RL19_BARBK
Sequence: MNIIAQLEAEQCAKIAEKRQLPAFQVGDTVRVMVRVTEGTRTRVQAYEGVCIARSGYGFNENFTVRKISYGEGVERVFPFYSPLIEGVELVRRGKVRRAKLYYLRALRGKAARIAEKRDYRKKNVQIVEEEVAPAVEANVETTTAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RIR1_SHV21
Sequence: MSQETIISNLIDMLKVSAGWDREANEISGRLFHKLMDMSSTETISQYMSLFGPLLEPHILEFIQNYEQEIDEVCLEYRASYDFMCLRNCGILPAKRFYDTYVLPPRTEMNGKYESIPHFFARIAAYCAWNCIMCEPLKDTLVYVQKRDWNVEIKTDMQIFKYFYKVISSQLVCCATPVMRSAGVAGENLSSCFIIAPTLDTEKSTISSIFGELAPLLASRSGVGVDVTKFSFGGKNIHSCLKLINAQVEFFNDKSVRPVSVATYIEVWHCQIHEFLSAKLPENPDRCNSIFQGVCVPSLFFKMYESDPNGLWYLFDPQDAPNLTRLYGLEFEEEYLRLVSEKKYKQSVTLKSLMFSLINTIIKTGSPYVISKEAMNKHHWYETQGEAINCSNLCAEIVQQPKQFTSTCNLANVCLPKCLNSSNFPYTCSNTAQFDFSKLEYAVQAAVFIINACILSPSPTSSATVGQRERSMGIGCHGLADVFSEMGYGYLDLESECLDRDIFETMYYTAVKTSSEICSVGKGQPFAGFRKSKLAHGVFHWATWDAMPQRVPMKQWIHLQDNIKKFGVFNSQFIALMPTAGTSQLTGYTDSFYPYFANMSSKVSNKEEIMKPNITFLKNVKPQDLCTVRFYGGDVSMMPEDVSTRYKHFLTAFDYCPEAQMRRASIRAPYVDQSQSLTLFLTEENVQSAKYLKDLLLLGFRLGLKTIMYYCRVKKTTKLLQLECLKLDEHTKKDAQIVLADLARELPDSHKTEDACPLDQSECIACQ
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, R1, Ribonucleotide reductase large subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: RBL_THAPS
Sequence: MSQSVSERTRIKSDRYESGVIPYAKMGYWDAAYTVKDTDVLALFRITPQPGVDPVEAAAAVAGESSTATWTVVWTDLLTACERYRAKAYRVDPVPSATDQYFAFIAYECDLFEEASLSNLTASIIGNVFGFKAISALRLEDMRIPHSYLKTFQGPATGIVVERERLNKYGTPLLGATVKPKLGLSGKNYGRVVYEGLKGGLDFLKDDENINSQPFMRWRERFLNCLEGINRASAATGEVKGSYLNITAATMEEVYKRAEYAKMIGSVIVMIDLVMGYTAIQSIAYWARENDMLLHLHRAGNSTYARQKNHGINFRVICKWMRMSGVDHIHAGTVVGKLEGDPLMIKGFYDILRLTELEVNLPFGIFFEMDWASLRRCMPVASGGIHCGQMHQLIHYLGDDVVLQFGGGTIGHPDGIQAGATANRVALEAMVLARNEGLDYFNQQVGPQILRDAAKTCGPLQTALDLWKDISFNYTSTDTADFAETATANR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.