PharMolix/UniProtQA huggingface dataset:
Protein: SYFB_METAR
Sequence: MATVTLNYPDLVKLIGIDLSLDKVREVMFELGSETEDIQGDEVTFEVTSDRADLLSEEGIARMLRAYYSIETGFRIPKLQPSGYKLIVNREVEPVRPYVTGAIVRNVQFTDESIKSLMHLQEKLHGTFGRKRKKGAVGVHDLSKIKGREIHYRAVPGDSVKFVPLQSDELMTLSDVLARHPKGIDYRYVLEGKNLMPIITDDEGIFSFPPIINSKRTEVTLNTHDLLIELTGEDLRTIDYMLNIVLYSLDLRGASIYSIDVVYPDETLHRPDFNVRNIDIEVDYVNRVLGLELTAPDIKALLERMGFKVAETGSDYLIVEVPPYRADILHKRDVVDDVGRAFGYNNITPSYPNTPSVGKLTEATKLGDAIRNTMIGLGCQDTFNFILIGKDEVFGKMNLPDDGTAVEISNPYAEQYNIVRTSLIPSLMIVLSNNLHRDYPQNIFEVGTVAHLDSAENTGVKEIDHVACTLCYAKAGFNEIKVKLQSLCANFGKLDELKTVAAEHPSFIPGRCAEVRIGDKKVGIIGELSPVVLKSWGIEMPVAAFEMEIAALK
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_ECO55
Sequence: MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVATGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RECX_PSEMY
Sequence: MLDNPLAVRRAAMDLLARREHGRVELTRKLRKRGAPDELIDGALDRLAEEGLLSEARYLESFVAYRARAGYGPQRIREELGQRGLARGDIDQALRDSGIDWFEQLRETWQRKYAGRLPNDARERAQQGRFLAYRGYSLDMIGRLLRGCDE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_HALHL
Sequence: MSSGDRKHASGGAVTVSRMRAMKREGRPLACLTAYDYGFAAACERAGVDLLLIGDSLGMVVQGHETTLPVTVDDMVYHTRCVARACRRALVVADLPFMSHTGVEQGLHNAGRLMKEGGAQMVKLEGGAEQAALVERLAQNGIPVCGHLGLKPQQVHKIGGYRVQGREQADAERMEADALALEAAGADLLILECVPAVLAQQLSERLTVPVVGIGAGGGCDGQILVLHDVLGVTEQPPRFARAFGAEGGGVHAALEAYVAAVRAGTFPGPEHGFEA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_WOLWR
Sequence: MNNAVKLNSIFTKLSKKKKPKLLGRGIGCGKGKTSGRGHKGQKARSGVSINGFEGGQQSIYTRLPKRGFKPIRRSIYSIINVGDIQRLMEAKKIVKDSVIDKERLYKLGFIKSIKDKIKLLNKGKLSEKFVFHVDFASEAAKKSVASVGGSVEILS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: YPDB_SHIFL
Sequence: MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQHNRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKPYQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEAHEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYILRLKDLDFEVPVSRSKVKEFRQLMHL
What is the function of this protein?
Member of the two-component regulatory system YpdA/YpdB.  YpdB regulates expression of yhjX by binding to its promoter region.
What are the official names of this protein?
Transcriptional regulatory protein YpdB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_MYCA1
Sequence: MIRIGTRGSLLATTQAGGVRDALIARGHPAELVTITTAGDRSSGPIESLGVGVFTTALREAIEEGRVDAAVHSHKDLPTADDPRFAVAAIPARNDPRDAVVARDGLVLGELPPGSLVGTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLGDVTETLEPVQMLPAPAQGALAVECRAGDSRLAAVLAELDDADTRASVTAERALLAELEAGCSAPVGAIAEVVESIDEDGRIFEELSLRGCVAALDGSDVIRASGIGTPGRARELGLSVAAELFELGARELMSGARHDPARGN
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: MPS2_YEASZ
Sequence: MSNGAFDAIFEYAWGQIDKPISGDFIYGKDLPKLIEIIENIFQKAQKSGSYELRLPLFSEINKDLFRTFSNTKTFFKIHKEEFDDIFFNLVNHPLREILENAFIGVDSIPSDFIVSMNLNSPSKFLVENKSKNTEGAGISTPRKKLTESPIKLLSRNNIGKALEVQVEELKRELTAKQSLLQENERQVSELKIRLETYQEKYASIQQRFSDLQKARQVEDNQNSSRTSDPGSPLVTGIDQKAILEEFRRRLQRQTDTISFLKDQIRRERGLNCSNDKVSHSKRKHATTDGDGTFKNFISAVPSNIWVKATIRIIVCFALLAGVLPYIRKYVYAHDTPSQNSRLQLSWWENSGILSKIVWFFEDQTDLETEYRSNANVDDAYSRVFGI
What is the function of this protein?
Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.
What are the official names of this protein?
Monopolar spindle protein 2.
What is the protein family that this protein belongs to?
Belongs to the MPS2 family.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: TS1R2_CEBPY
Sequence: MGPRARTVCFLFFLLWVLAELAENSDFHLPGDYLLGGLFTLHANMKGIVHLNFLQVPMCKEYEMKVSGYNLMQAMRFAVEEINNDSSLLPDVLLGYEMVDVCYISNNVQPALYFLAQEDNLLPIQEDYSNYVPRVVAVIGPENSESVMTVAHFLSLFLLPQITYSAISDQLQDKQRFPALLRTTPSAKHHIEAMVQLMLHFHWNWISVLVSSDTYGRDNGQMLGDRLAGGDICIAFQETLPTLQSNQDIMPEDHQRLVSIVEKLQQSTARVVVVFSPDLSLYNFFREVLRQNFTGAVWIASESWAIDPVLHNLTGLHRTGTFLGITIQNVPIPGFSEFRVRGPQAGPTNQRSTCNQECDTCLNSTLSFNTVLRLSGERIVYSVYSAVYAVAHALHSLLGCDHSTCTKRVVYPWQLVQEIWKVNFTLLDHQIFFDPQGDVALHLEIVQWQWDLSQNPFQSIASYNPLQGRLKHIQDISWHTINNTIPVSMCSKRCQSGQKKKPVGIHTCCFECIDCLPGTFLNQTEDEYDCQACPSNEWSHQSETSCFKRRLSFLEWHEAATIAVALLAALGFLXXXXXXXXXXXXXXXPMVRSAGGPMCFLMLTLLLVAYMVVPVYVGPPKVTTCLCRQALFPVCFTICISCITMRSFQIVCVFKMASRFPRAYSYWVRYQGSYVSVAFITALKVVTVVISLLATGLNPTTRADTDDPKIMIISCNPNYRNSLLFNTSLDLLLSVVGFSFAYMGKELPTNYNEAKFITFSMTFYFTSSVSLCTFMSVYDGVLVTIVDLLVTVFNLLAISLGYFGPKCYMILFYPERNTPAYFNSMIQGYTMRRD
What is the function of this protein?
Putative taste receptor.  TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners (By similarity).
What are the official names of this protein?
Taste receptor type 1 member 2, Sweet taste receptor T1R2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PMEI5_ARATH
Sequence: MATMLINHMLFLTSLLIVVFPVANAIPARDIDKLCKETTDVPFCLKYLGTDPRIPAARDLTDVLLIAITQSKMQVDDATTHIDRVRRKFNGPHGRRRIEVCKTNYGIASARFHTAWELGLQKSFWDVEKLARIGTNAVIDCENVWRRDGPIQTSPLTFYNMNVFKLSGIILLIFNKLVT
What is the function of this protein?
Pectin methylesterase (PME) inhibitor that targets PME from seeds and modulates PME activity and pectin methylesterification during seed germination.
What are the official names of this protein?
Pectinesterase inhibitor 5, Pectin methylesterase inhibitor 5, AtPMEI5.
What is the protein family that this protein belongs to?
Belongs to the PMEI family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: GUAA_FRATF
Sequence: MTDIHNHKILILDFGSQYTQLIARRVREVGVFCEIFPHDVAADFIKNYQAKGIILSGGPESVYDSDVKAPEIVFELGVPVLGICYGMQTMVMQHGGEVKGADQSEFGKAIINILNLTNNIFSNMEHEQLVWMSHSDKVTQTGEHFEIIASSTNAPVAAVAHKNKPFFGVQFHPETTHTENGKQIIENFVVNICGCDTLWNIENIIENDIKEIKQKVGTDKVILGLSGGVDSSVVAAILHQAIGDQLTCIFVDTGLLRLNEGDQVMQVFAEHMDINVIRINAKNRFLDALRGICDPEQKRKIIGKLFVDIFDEEAAKIENAKWLAQGTIYSDVIESAGNNQSKAHVIKSHHNVGGLPKEMKLKLLEPLRELFKDEVRKLGLGLGLPYNMLYRHPFPGPGLGVRILGEIKKEYVETLQKADAIFTEELYKHNLYHDVSQAFGVFLPIKSVGVVGDQRRYEYVIALRAVVSIDFMTATWANLPYDFLSLVSNRIVNEVKQVSRVVYDVTGKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: SUI1_SULAC
Sequence: MSDLCGGLPPDICEQLTKEEQFIKIKVEKRRYGKEVTIVEGISNDETELKKIASELKSKLAAGGTVKNGKIELQGDHRDRVKELLIKMGFPESNILVIE
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: Y188_ARCFU
Sequence: MKQVDCIGLYCPEPVFRARKAMEESEVGEIIEILADDPAAESDIPVLVKKLGQELVEFEKLEDGVLRFVVKIVKEVR
What are the official names of this protein?
Putative sulfur carrier protein AF_0188.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
Protein: TYPH_AERS4
Sequence: MFLPQEIIRKKRNGEALSTQEIQFFVQGITNNTIGEGQIAALAMAVYFKDMTMDERVALTCAMRDSGMVLNWEHLNLGGPIVDKHSTGGVGDVVSLMLGPMVAACGGFVPMISGRGLGHTGGTLDKLDAIPGYQTSVDNDRFLKVVKEAGVAIIGQTGDLAPADKRIYAVRDITATVESIAMITGSILSKKLASGLEALVMDVKVGSGAFMPTFEASEELAKSIVAVANGAGCRTSALLTDMNQVLASSAGNGVEVREAVRYLTGEYRNPRIHEVTMSLCAEMLISAHLASDDADARRKLQAVLDNGKAAEIFGRMVTGLGGPSDFMERYDSYLPKAAIVRPVYAANAGFVTAMDTRELGLAVVAMGGGRRAAGDKLDYAVGLTDFIRLGQSVDADKPLALIHAQTEDQFAQAASMVQAAVKIGDTQPQALPEVYRRIGLADL
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: LIPA_RICB8
Sequence: MSKRPDWIKVKAPNSSEYYNTKDLIKNLKLNTVCEEAACPNIGECWSKKHATVMILGSVCTRACRFCNVKTGRPDLLDPHEPQRLAEAVQKLGLKHVVITSVDRDDLEDGGATHFAECISEIRKSSPNTTIEILTPDFLRKDGAAEIIANAKPDVFNHNVETVPSLYNTIRPGARYYNSLSLLHNIKKLSPEVFTKSGMMVGLGEEISEVVQVMDDLREAKVDFLTIGQYLQPTKNHAEVAKYVTPEEFKYLERVARTKGFLMVSASPLTRSSYHADEDFEKLKENYRHRHCEERRSIDVAIS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YUZB_BACSU
Sequence: MNPMIEFCVSNLAHGSQEARAILEKDPNLDVLEYGCLSYCGTCMESLFALVNGEVVMGETPAELVENIYTFIEENPMF
What are the official names of this protein?
UPF0349 protein YuzB.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: SHEP_DROSI
Sequence: MHPRYSPAPPPQQQQQMGGPPHQQQGGGGGGGGNMRGPSNAQQLPPQIPRSQNYSNGSSSSAAAAPLTSRSAFPGAPLTASAVALKGALPQRPPAMTSPAAAAAGAALAAGAPYRGAASWTPQGYAPAAAAAAAAVAQQAAYRYTAPLPQPAYAAYTPHTATTPATTTYGQRVPTAASPSNTNSSSSSNTGSQSGTLSTSLSNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCYGFVDFEQPAFAECAVKGLQGKGVQAQMAKQQEQDPTNLYIANLPPHFKETDLEAMLSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGNTIPGAKDPLLVKFADGGPKKKNLFKTPDPNARAWRDVSAEGIPVAYDPTMQQNGVSVNVGTPIGVPYSRFSAPQVGGYPVAGSQWIPGYMMTTQVDDQTSYSPQYMQMAAAPQLGVTSYKPEAVNQVQPRGISMMVSGDTGVPYGTMMPQLATLQIGNSVSHRSPYYAPPPTIIPTMPMTDSEQASTAASPDEAYTQYPHQAAPK
What is the function of this protein?
Has a role in the perception of gravity.
What are the official names of this protein?
Protein alan shepard.
Protein: RL2_CALS4
Sequence: MGIKAYKPTSPGRRQMTVLTFEEITKKEPEKSLLAPLTKKAGRNVYGRITVRHRGGGHKRRYRIIDFKRDKDGIPGKVAAIEYDPNRTAFIALIHYADGEKRYIIAPHGLKVGDIVESGENVDIKVGNALPLRNIPVGTIVHNIELIPGKGGQLVRAAGAAAQLMAKEGDYVHIRMPSGEIRLINANCRATIGQVSNIDHENVKIGKAGRSRWLGIRPTVRGSAMNPVDHPHGGGEGKAPIGHPGPLTPWGKPALGYKTRKKGKASDKFIVKRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ARHG9_MOUSE
Sequence: MYDLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVIDIEDGRDDDFNVSMKNAFKLHNKETEEVHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKASKQKGVNSARSVPPSYPPPQDPLNQGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK
What is the function of this protein?
Acts as guanine nucleotide exchange factor (GEF) for CDC42.  Promotes formation of GPHN clusters (By similarity).
What are the official names of this protein?
Rho guanine nucleotide exchange factor 9, Collybistin, Rac/Cdc42 guanine nucleotide exchange factor 9.
What are the subcellular locations of this protein?
Cytoplasm. Postsynaptic density.
Protein: NADD_BACCZ
Sequence: MRKIGIIGGTFDPPHYGHLLIANEVYHALNLEEVWFLPNQIPPHKQGRNITSVESRLQMLELATEAEEHFSICLEELSRKGPSYTYDTMLQLTKKYPDVQFHFIIGGDMVEYLPKWYNIEALLDLVTFVGVARPGYTLHTPYPITTVEIPEFAVSSSLLRERYKEKKTCKYLLPEKVQVYIERNGLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RODZ_ECO5E
Sequence: MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSLGKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELSSNSEQGQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPVVTAPAPAVDPQQNAVVSPSQANVDTAATPAPTAATTPDGAAPLPTDQAGVTTPVADPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQSPAQ
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: ATG18_PICST
Sequence: MLKAQSAAAGSLHQTLSQYSASIATDGSSSVTGSFKTDDSVNFITFNQDASCIAVGLNNGYKIFNCKPKFGKCYQIRKEESVGIIEMLYCTSLLAIVALGEEPGSSPRKLKIVNTKRQTTICDLIFPSTILQVKLTKSRLIVLLEEQIYIYDITTMKLLHTIETSPNSIGLCALSTTPDNDGNNYLAYPSPPKTITHDSLLASGINTNGGTNSVVNNISSVSNSPNRVGDVIMFNLNTLQPMSVIEAHKSALAAITLSSDGSLLATASDKGTIVRVFSVATGVKLFQFRRGTYSTKIYSLSFSSDNNYVVATSSSETVHIFRLGESEALENKHKKKKASTPKPTQPETIEEEDATLLQERPSQESTQDDDEFADDGDDSDEAVEGDDNDDESLEVISNKQRKLSQGSSNSFASFNSGTDDSSQAAKNEPLIDQNRLSVARLIRRSSQTLGRKAAQRMGDFLPSRFSSILEPTRHFASLKINAIGKDVKSIAVMNNELQEDLVPQAFLMRKDSDSYLSKEMLSLNLLHIYVVTSEGFFYTYGLDPERGGDCILLHQYSLIDESN
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct ATG9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: RS14_BRUC2
Sequence: MAKTSAVEKNKRREKLVKRHAVKRARLKAIVMDQGLPLEERFRATIRLAELPRNSAKVRIRNRCEVSGRPRGYYRKLKMSRIALRQLGSLGQIPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: TGS1_HUMAN
Sequence: MCCEKWSRVAEMFLFIEEREDCKILCLCSRAFVEDRKLYNLGLKGYYIRDSGNNSGDQATEEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAHKDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAAVPELAKYWAQRYRLFSRFDDGIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEVYGIADKIEFICGDFLLLASFLKADVVFLSPPWGGPDYATAETFDIRTMMSPDGFEIFRLSKKITNNIVYFLPRNADIDQVASLAGPGGQVEIEQNFLNNKLKTITAYFGDLIRRPASET
What is the function of this protein?
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure.  The enzyme is specific for guanine, and N7 methylation must precede N2 methylation.  Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs).  Plays a role in transcriptional regulation.
What are the official names of this protein?
Trimethylguanosine synthase, CLL-associated antigen KW-2, Cap-specific guanine-N2 methyltransferase, Hepatocellular carcinoma-associated antigen 137, Nuclear receptor coactivator 6-interacting protein, PRIP-interacting protein with methyltransferase motif, PIMT, PIPMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Note=A 90 kDa isoform is found in the nucleus while a 55 kDa isoform is found in the cytoplasm and colocalizes with the tubulin network.
Protein: FTHS2_STRPM
Sequence: MVLSDIEIANSVTMEPISKVANQLGIDEEALCLYGKYKAKIDARQLVALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNYQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKANLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACDKRGVDVVISDVWANGGAGGRELAEKVVALAEQDNQFCFVYEEDDSIETKLTKIVTKVYGGKGIRLTPAAKRELADLERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFTVTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 2, Formyltetrahydrofolate synthetase 2, FHS 2, FTHFS 2.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: LGT_BURMA
Sequence: MIIHPNFDPVAIHLGPLAVRWYGLMYLVGFILAIVVGRLRLKLPHVAAQGWSAKDIDDMMFYGVLGVVLGGRLGYVLFYKAGYYFSHPLDIFRVWEGGMSFHGGFLGVTLAMALFAWQRKRHWLEVTDFVAPMVPTGLAAGRLGNFINGELWGRVTSPDAPWAMLFPGASRDDAAWLAAHQDIAAKWNLNEVFLSHQMLPRHPSQLYEIALEGIALFFVLWFFSRKPRPMGAISALFLIGYGAARFTVEFAREPDDFLGLLTFGLSMGQWLSLPMIVAGVLMMIWAYRRGGVAKQA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LSM12_CHICK
Sequence: MAAPGECFSVGSQVSCRTCQEQRLQGEVVAFDYPSKMLALKCPSSSGKPNHADILLVNLQYVSEVEIINDRTETPPPLASLNVSKLANKARMEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVIAPPYQVENCKGKEGSALGHVRKIVEKHFRDVESQKVMQRSQAQQTQKESALSS
What is the function of this protein?
Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein.
What are the official names of this protein?
Protein LSM12.
What is the protein family that this protein belongs to?
Belongs to the LSM12 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_ANADE
Sequence: MYFQDLILKLQSYWASRNCILAQGYDQEVGAGTMNPSTFLRVLGPEPWNVAYVEPSRRPADGRYGENPNRLYQHHQFQVILKPNPPDVQELYLGSLRAIGIDPREHDIRFVEDDWESPTLGAWGLGWEVWCDGMEITQYTYFQQAGGFEVKPVAAELTYGLERIAMYLQDVENVFDVEWVKGVKYREVFHRNEVEMSTYSFQASDPKMLFGLFDTYEAECKRLIGLKLPLPAYDYCLKCSHAFNNLDARGAISVTERAAYIGRVRALAHDCAKGYLDSREALGFPLLPPADRKQAVEAARAAREARESR
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEY1_XENTR
Sequence: MKRGHDYSSSDSELDENIEVEKESADENGNLSSAAGSMSPSTSSQILARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGMDTTDPLRVRLVSHLNNYASQREAANTAHTGIGHIPWGGTFAHHPHLSHPLLLAQTAHTSANSTSSSTEAHHQNRLPGSPHAETSSLRVPPNGNIASVLPVVASSKLSPPLLSSMASLSAFPFSFGSFHLLSPNSLSPTTPTPSGKPYRPWGTEIGAF
What is the function of this protein?
Downstream effector of Notch signaling.  Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'.  Acts as a suppressor of neurogenesis by antagonizing proneural gene function.  Functions during floorplate development.  Plays a role in pronephros formation in the inhibition of distal tubule and duct cell fates and the promotion of glomus and proximal tubule formation (By similarity).
What are the official names of this protein?
Hairy/enhancer-of-split related with YRPW motif protein 1.
What is the protein family that this protein belongs to?
Belongs to the HEY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCDB_MYCTU
Sequence: MLLSDRDLRAEISSGRLGIDPFDDTLVQPSSIDVRLDCLFRVFNNTRYTHIDPAKQQDELTSLVQPVDGEPFVLHPGEFVLGSTLELFTLPDNLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCMLRLTSPSEHPYGSSRAGSKYQGQRGPTPSRSYQNFIRST
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.  It also acts as a dUTP diphosphatase.  Affinity for dCTP and dUTP are very similar.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.