PharMolix/UniProtQA huggingface dataset:
Protein: NDK_POLSJ
Sequence: MAIERTLSIIKPDAVAKNVIGQIYARFEAAGLKVVAAKMAHLSKGEAEAFYAVHKERPFFKDLVSFMISGPVMIQALEGEGAILKNRDLMGATDPKKAAAGTIRADFADSIDANAVHGSDAVETAQAEIAFFFPGMNIYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRF8_ORYSJ
Sequence: MLSSCGGHGHGNPRSLQEEHHGRCGEQQGGGGGGGQEQEQDGFLVREARASPPSPSSSSFLGSTSSSCSGGGGGGQMLSFSSPNGTAGLGLSSGGSMQGVLARVRGPFTPTQWMELEHQALIYKHIAANVSVPSSLLLPIRRSLHPWGWGSFPPGCADVEPRRCRRTDGKKWRCSRDAVGDQKYCERHINRGRHRSRKHVEGRKATLTIAEPSTVIAAGVSSRGHTVARQKQVKGSAATVSDPFSRQSNRKFLEKQNVVDQLSPMDSFDFSSTQSSPNYDNVALSPLKLHHDHDESYIGHGAGSSSEKGSMMYESRLTVSKETLDDGPLGEVFKRKNCQSASTEILTEKWTENPNLHCPSGILQMATKFNSISSGNTVNSGGTAVENLITDNGYLTARMMNPHIVPTLL
What is the function of this protein?
Transcription activator that plays a regulatory role in gibberellin-induced stem elongation.
What are the official names of this protein?
Growth-regulating factor 8, OsGRF8, Transcription activator GRF8.
What is the protein family that this protein belongs to?
Belongs to the GRF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTH_CHESB
Sequence: MLLLAGLGNPGPQYQNHRHNVGFMAADAIFRRHSFSPWSKKFSALVAEGRVGTEKLLLVKPQTFMNLSGQAVGEAMRFYKLQPSDIIVFYDELDLAPGKVRVKRGSGSGGHNGIKSIDAHCGQDYRRVRIGIGHPGDKARVTPHVLGDFAKADHAWLDPLLDAMAENVDLLITGDESGFMNKASLAVQGKAADIEMAGEKPAQKGRSHIRQARPKAPPAELPSSGPMAAMLKKLFGGKE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANM7_DROSI
Sequence: MLRNFLKSRFLAPRGMSCFSQVMNPITGQNSWQERGDDYDYHLEVANAGFGDMLHDWERNQKYFAALRKTIAGMREAGREVHVLDIGTGTGILSMMALAAGADSVTACEAFLPMANCAEKILAANGAGDKVRLIRKRSTEIQVGEDMPRKANLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVAQSPLAAQWNSLKTIANLDGEPLLHPPEQLKSCQGEAALHDVQLSQLPSSAFRPLTDPVEIFQFDFQRKQEREKQRAQLLKLQSKQPGAAELVFYWWDIQLDDGGEILLSCAPYWAHPQLKELAAEKAKDHPLPNVVPWRDHWMQAIYYIPKPLQLLEAGKSFHLSCHHDEYSLWFDAREEAPTKSVRRHTCTCDLHMTYSRSRIGQLNQSPRNKRYLRYLEESIEAEKSNVLVLGNGCLLGLASSALGAASVLLHEPHRFSRRLLESIVKHNQLKNVHFLDKVEELEDSQLAALTHIFAEPYFLNAILPWDNFYFGTLLTKIKDKLPEGVKILPCSARIYALPVEFLDLHKIRAPVGSCEGFDLRLFDEMVERSAEQAVSLVEAQPLWEYPCRALSEPQEVLSVDFSNFGQEHSLKGSIELKHTGICNGVALWVDWKLVEDNSPRSIVSSGPSEPVVPGEFVKWDMFVRQGVHFPRKPKDAVTHLEWSTDFKPLLGELNFSFGQKKL
What is the function of this protein?
Essential arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).  Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins SmD1 and SmD3 (By similarity).
What are the official names of this protein?
Protein arginine N-methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
Protein: DEFD4_SPIOL
Sequence: MFFSSKKCKTVSKTFRGPCVRNA
What is the function of this protein?
Antimicrobial peptide.  Active against Fusarium spp. , Gram-positive and Gram-negative bacterial pathogens.
What are the official names of this protein?
Defensin D4, Antimicrobial peptide D4, So-D4.
What is the protein family that this protein belongs to?
Belongs to the DEFL family. Group IV subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RUVB2_CRYNB
Sequence: MAANISLQPTSMRDVTKMERIGVHSHIHGLGLDSNLEPRASSQGMIGQGKARKAAGVILKMVQEGRIAGRAILMAGPPSTGKTALAMAMTQTLGSDVPFVMLTASEVFSLEISKTESLTQAFRRAIGVRIKEETELIEGEVVEIQVDRSVTGATKTGRLTLKTTDMETVYDLGSKMIDQLQKEKVLAGDVVSIDKASGRISKLGRSFGRAKDYDAMGADTRFVACPDGELQTRKEVVHTVSLHEIDVINSRTQGFLALFAGDTGEIKPELRAQINGKVAEWREEGKAEIVPGVLFIDEVHMLDIECFSFLNRAMENELAPLVVMASNRGITRIRGTKYKSPHGIPADLLDRMLIISTNRYEEDEMREIVKIRAEEEDVRLSPAALDLLATMGIQTSLRYSLNLIAPSSLLAQRRKSPQTDVEDVRMAYKYFCDVERSAQYAKETSGMMFGETEEINGGMEVDA
What is the function of this protein?
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.  The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair.  Also involved in pre-rRNA processing (By similarity).
What are the official names of this protein?
RuvB-like helicase 2.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXJ_PSEPF
Sequence: MTISNRILLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVLLLKDVLQTRMNFEMGVTEEMMAFAERIRPAHICLVPETRQELTTEGGLDVAGQEERIRAAVERLSKIGSEVSLFIDADERQIAASKRVGAPAIELHTGRYADAETPSEVAEELKRVADGVAFGLAQGLIVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKSAVSEMKTLILAAARH
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_HELPJ
Sequence: MQFHSSSALITPFKKDLSVDEAAYETLIKRQIFQGMDACVPVGTTGESATLTHKEHMRCIEIAIETCKSTKTPSNSRMKVLAGVGSNATSESLSLAKFAQKIGADAILCVSPYYNRPTQQGLFEHYKTIAQSVEIPVMLYDVPSRTGVSIEVPTALKLFREVPNIKAIKEASGSLKRVTELHYYEKDFKIFSGEDSLNHSIMFSGGCGVISVTGNLMPNLISQMVNCALKFEYQQALEIQNKLFDLHQALFVETNPIPIKMAMHLAGLIENPSYRLPLVAPSKETIKLLEKTLQQYEVIA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BICL2_DANRE
Sequence: MAPTMGVDDLLASPQDDRSPTLLEKDLILAAEVGQALLEKNEELASQIMQMESEMEAMQQEKHMVQRRLEVRDLEASQREAELQADISALRAQLEQKHIQGRDRRREESEQLIQLSNHNQKLVEQLAEAVSLEHTLRTELRTLREEMEDTSFSKSISSARLDSLQAENRVLKERCTHMDERLKSTQEDNERLRSERDGLRERAIELQTSLKDKETELEQEHSTVFQLRTVNRTLQQRVQALGEEASLGEATCFPLSLQSEIQQCQAKETILAHSSVLREKEEEIQRLQKELQSRETELEGLREEVKLFRNSPGKPTYKALEEEMILARQERDALNQQLLNTIRHKVALSQEVESWQEDMRLVICQQVQLQQQEKEKENNKERTGFQRGTRTTKSLRLRGEEGRKGFFSALFGGD
What are the official names of this protein?
BICD family-like cargo adapter 2, Bicaudal D-related protein 2, BICD-related protein 2, BICDR-2, Coiled-coil domain-containing protein 64B.
Protein: ATPG_STRPC
Sequence: MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQIYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSVMDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVDMFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDILDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAITQEITEIVAGANALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS15_LACCB
Sequence: MAIEQTQKDEIIKQYARHDGDTGSPEVQIAVLTAEILALNDHLSVHKKDHHSYVGLMKKIGHRRNLLAYLRNKDITRYRDLIKALGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: KTHY_STAEQ
Sequence: MSTFITFEGPEGAGKTSVIKKVSERLAKEYDIVTTREPGGVLTSEEIRRIVLDGDSIDIRTEAMLFAASRREHLVEKIIPSLQAGKIVLCDRYIDSSLAYQGYARGIGIKEVKLLNEFAINGLYPDLTIYLDVDAEIGRQRILKNNREQNRLDKEEKAFHEKVIEGYQKVISDNPHRFIKVNANHSLDKVVEETYQSIIKYLK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RIOK3_MOUSE
Sequence: MDLVGVSSPEPGPAAAWGPSKCPWATPQNTVSCSLTEVMSEELAKELQLEEEAAAFPEVVVAEGPFISGENIDTSSDLMLAQMLQMEFDREYDAQLRREEKKFNGDSKVSISFENYRKVHPFEDSDSSEDEVDWQDTRDDPYRPAKPIPTPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPGFQVGDGIGMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSLEDEKEDGKAIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLTRMQKAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLSNEEMKDAYYQTLHLMQQLYNECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVTEALNERELFNAVSGLNISADNEADFLAEIEALEKMNEDHIQKNGRKAASFLKDDGSPPVLSAD
What is the function of this protein?
Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.  May act as an adapter protein essential for the recruitment of TBK1 to IRF3.  Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling.  Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway.  May play a role in the biogenesis of the 40S ribosomal subunit.  Involved in the processing of 21S pre-rRNA to the mature 18S rRNA.
What are the official names of this protein?
Serine/threonine-protein kinase RIO3, RIO kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAP_YEAST
Sequence: MSSQKVFGITGPVSTVGATAAENKLNDSLIQELKKEGSFETEQETANRVQVLKILQELAQRFVYEVSKKKNMSDGMARDAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVTREDFFTVFDSLLRERKELDEIAPVPDAFVPIIKIKFSGISIDLICARLDQPQVPLSLTLSDKNLLRNLDEKDLRALNGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIFGFPGGVAWAMLVARICQLYPNACSAVILNRFFIILSEWNWPQPVILKPIEDGPLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITNDIFSNKKSWANLFEKNDFFFRYKFYLEITAYTRGSDEQHLKWSGLVESKVRLLVMKLEVLAGIKIAHPFTKPFESSYCCPTEDDYEMIQDKYGSHKTETALNALKLVTDENKEEESIKDAPKAYLSTMYIGLDFNIENKKEKVDIHIPCTEFVNLCRSFNEDYGDHKVFNLALRFVKGYDLPDEVFDENEKRPSKKSKRKNLDARHETVKRSKSDAASGDNINGTTAAVDVN
What is the function of this protein?
Polymerase component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.
What are the official names of this protein?
Poly(A) polymerase, PAP, Polynucleotide adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the poly(A) polymerase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DP96R_ASFB7
Sequence: MSTHDCFSKEKPVDMNDISEKSSVVDNAPEKPAGANHIPEKSAREMTSSEWIAEYWKGIKRGNDVPCCCPRKMTSADKKFSVFGKGSLIRSIQKNN
What is the function of this protein?
Inhibits cGAS-STING-mediated type I IFN expression and NF-kB activation by inhibiting TBK1 and IKBKB/IKKB (PubMed:30348523).  Inhibits host TBK1 phosphorylation (PubMed:30348523).
What are the official names of this protein?
TBK1 inhibitor DP96R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus DP96R family.
Protein: RAV1_YEAST
Sequence: MSLNFLPGRPNATPQTACQATWQNHTIFAYCSGNNLIILTNKFTRLQTIYTQSDCTAVDINSQNGFIALSFHNRVLIYKPIHQIMQNPKWTQCCQLFHDDTPVNCLRWSSDNELAIGSDFLSFWKIKDNFGVYQPILQWNQKQPKPVYNVIISQDSQLIVSIGKYDCNAKLWKRVSIVGEQAIFNLTMLPHPKPITAMRWKKEPDQVSKNNTASHALYTLCEDKVLRIWSCFEMEKNHTVQIWGEVPLSPTQKFCVIIDNWIIRQTLSVKDSEIFDISDSDIVILGSMTGEMEVLALNNLSQDPPKPMTKKTISHKKVKKATMLNDTRYLYLPEIQPYDNVKGKLSFLVHDLQGVIRHLLIDILQLINNKTEDLSAALEHKFTGHNKSVQKLVRSSDGEALLTTSRFSENGVWYPQKLNHGVSLRLQNTIQTESPIKFAVVHELGKQVICLLENGALQAWECPTNRKEDSEQKQSYLRVETRLKEEKKIHPIVMLNTPEPKHSHERHFTALIFSDGSIKAFEVSLTRGIFEVKSDSLDIDGDDIYKISIIDPVHQTFVSNRPLISLITKKGLTRTYKAIVNYNDRHVQWIKACEINTGIMNCTCIRGSSTGKLCIVNSTGKVMSLWDLNRGVLEYEETFHNPIEDIDWTSTEYGQSIVSIGFTGYALLYTQLRYDYTNNTPSYLPIEKIDITAHTAHNIGDSVWMKNGTFVVASGNQFYIKDKSLDLTDPFTYQSIGSRKILSNDILHLSSVLNGPLPVYHPQFLIQAIYANKLQLVKELLLRLFLALRKLDFESQDVSNLDSNLGMDPLKYFIAKDRDYPVESFPDPYPCFNKTVSLALTEQLTKTTLPYLTRHQQITLITVIEAVDEVTKNENIVDYNGVRFLLGVKLFLSHKNIQKSILMRDVSWALHSDNKEILLSSIDRHITSWNRAREYRIAYWIKEQDLVKKFEDIAKYEFSKDDKRDPSRCAIFYLALKKKQILLSLWKMAIGHPEQQKMVRFISNDFTVPRWRTAALKNAFVLLSKHRYMDAAVFFLLTDSLKDCVNVLCKQVHDMDLAIGVCRVYEGDNGPVLGELLTAQMLPETIKENDRWKASFIYWKLRKQEVAIKALLTAPIDLENNSSIVDKEVCVNRSFLVEDPALLYLYNHLRNRNLKYFIGSLNVEAKIECTLILRVTDILCRMGCNYLAVSLVKNWKFIERNSIPVQKLLKSPTKDRAYSAIGAMASEPISTARMRPSLFDKFGSPSASDIESPNPKLPNSLLDDFLQPPPNSTSSNSLAQSSSSAPRSILDEFVSPSYSQHKENLTPKAPNDSVGETDNSENRKDKLSKDILDDLSSQKPQKPKKSAITKNLLDDFV
What is the function of this protein?
Component of the RAVE complex, which is required for stable assembly of the vacuolar ATPase complex V-ATPase under many conditions.  Required for transport between the early endosome and the late endosome/prevacuolar compartment (PVC), suggesting that assembly of vacuolar ATPase at the early endosome is required for transport from the early endosome to the PVC.
What are the official names of this protein?
Regulator of V-ATPase in vacuolar membrane protein 1, Suppression of the onset of impotence protein 3.
What are the subcellular locations of this protein?
Endomembrane system. Note=Probably membrane-associated, associates with high density membrane compartment like early endosomes.
Protein: DCUP_MYCTU
Sequence: MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACEITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQAIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHALMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVPMTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAVVLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_CORGB
Sequence: MRVLAAMSGGVDSAVAASRAVAAGHEVVGVHLALSQDPQTVRESSRGCCSLEDSADARRVCDKLGIPFYVWDFSDRFKEDVIDNFIDSYAIGETPNPCLRCNEKIKFAALLERGIALGFDAVVTGHYARLTQPADGGDGYLRRGVDPNKDQSYVLGVLGAHEIEHCMFPVGDTIKPEIREEASAAGFSVAKKPDSYDICFIPDGNTQAFLGKHIGMRPGMIVDQEGTQLREHAGVHEFTIGQRKGLDIKAPAADGRPRYVTDIDAKTGTVTVGTRENLKISTIHADRLKFLHPAMDGQIDCEVQVRAHGGVVSCSATIDRDADFMVLNLNEPLQGVARGQAAVLYLPDADGDIVLGSGTICHTES
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_DICNV
Sequence: MSKIIDILEKEQIRTDLPEFGPGDTLVVQVKIREGNNERLQAFEGICIAKRNRGIGSSFTVRKISHGEGVERVFQTHSPLVSSVTVKRRGDVRRAKLYYLRALQGKAARIKEKLEKKASV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: MET_FELCA
Sequence: MKAPAVLAPGILVLLFTLVQKSYGECREALVKSEMNVNMKYQLPNFTAETPIQNVVLHKHHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGVWKDNINMALLIDTYYDDQLISCGSVHRGTCQRHVLPPSNTADILSKVHCMYSPQADEESSHCPDCVVSALGTKVLISEKGRFINFFVGNTINSSYLTDHSLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYIHAFESNRFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECILTEKRRKRSTREEVFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSSTPHVNFRLDSHPVSSEAIVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCHDKCVQLEECPSGTWTQEICLPTIYEVFPTSAPLEGGTMLTVCGWDFGFRRNNKFDLKKTRVFLGNESCTLTLSESTTNMLKCTVGPAVNEHFNISIIISNGRGTAQYSTFSYVDPVITSIFPSYGPKTGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSDSILECYTPAQTIPTEFPIKLKIDLANREMNSFSYQEDPIVYAIHPTKSFISGGSTITAVGKNLNSVSVLRMVISVHETRRNFTVACHHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNPVFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCETIYSDSEAVLCKVPNDLLKLNNELNIEWKQAVSSTILGKVIVQPDQNFTGLIVGVISISIILLLLLGVFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDLSPMLNSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNIDGEGDT
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: U7B10_ARATH
Sequence: MGQTFHAFMFPWFAFGHMTPYLHLANKLAERGHRITFLIPKKAQKQLEHLNLFPDSIVFHSLTIPHVDGLPAGAETFSDIPMPLWKFLPPAIDLTRDQVEAAVSALSPDLILFDIASWVPEVAKEYRVKSMLYNIISATSIAHDFVPGGELGVPPPGYPSSKLLYRKHDAHALLSFSVYYKRFSHRLITGLMNCDFISIRTCKEIEGKFCEYLERQYHKKVFLTGPMLPEPNKGKPLEDRWSHWLNGFEQGSVVFCALGSQVTLEKDQFQELCLGIELTGLPFFVAVTPPKGAKTIQDALPEGFEERVKDRGVVLGEWVQQPLLLAHPSVGCFLSHCGFGSMWESIMSDCQIVLLPFLADQVLNTRLMTEELKVSVEVQREETGWFSKESLSVAITSVMDQASEIGNLVRRNHSKLKEVLVSDGLLTGYTDKFVDTLENLVSETKRE
What are the official names of this protein?
UDP-glycosyltransferase 79B10.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: RPOB_STAS1
Sequence: MAGQFVQYGRHRKRRNYARISEVLELPNLIEIQTKSYDWFLEEGLLEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEESKNRDTTYSAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKLDKNGRTNFDATIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSTDQEIVDLLGDNEYLRNTLEKDGTETTDQALLEIYERLRPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKANKKLHLKHRLFNQKLAEPIVNTETGEIVAEEGTVLDRRNLDEIMDVLEANANSEVFELEGTVIDEPVEIQSIKVYVPNDEEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGFTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTDSVTPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELTHKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLETNSITDQIDYLTADEEDSYVVAQANSTLDENGRFIADEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMNPESPFVGTGMEHVAARDSGAAIVAKRKGRVEHVESNEILVRQLIEEDGQEYEGELDRYPLAKFKRSNTGTCYNQRPIVASGDVVTKGEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVSDSALKNLDDRGIVYVGAEVNDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKLVPEEDMPYLPDGTPIDIMLNPLGVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGASDEDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYESIVKGENITKPGVPESFRVLMKELQSLGLDVKIMDEHDNEIDMQDNEEEDVVERKVDLQQKDAPQSQKEVTD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: GPR17_HUMAN
Sequence: MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESSLSAKSEL
What is the function of this protein?
Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs).  Signals through G(i) and inhibition of adenylyl cyclase.  May mediate brain damage by nucleotides and CysLTs following ischemia.
What are the official names of this protein?
Uracil nucleotide/cysteinyl leukotriene receptor, UDP/CysLT receptor, G-protein coupled receptor 17, P2Y-like receptor, R12.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DDLB_XANCP
Sequence: MSTQIAPARISDPAAFGRVAVLLGGTSSEREVSLNSGSNVLDALRARGVDAQPVDGIPALAQALVAQRFDRVFNVLHGHNGGGEDGIVQGLMEAFGVPYTGSNVLGSALSMDKIRTKQVWLSLGLSTPRYARLAAGASAQQIHAAAEQIGLPVIVKPANEGSSVGVSRVFDQAQLDEAVTLAARYDGALLMEQLIEGDELTVAVLGDVALPSIRIVPKGQWYDYNAKYIAEDTQYLCPGLDGDAEAQIGQLALDAFRAAGCSGWGRVDVMRDGSTGQLYLLEVNTAPGMTSHSLVPKAARQLGIDFEALVWRVLEQTL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase B, D-Ala-D-Ala ligase B, D-alanylalanine synthetase B.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAX44_TITOB
Sequence: VFINVKCRGSKECLPACKAAVGKAAGKCMNGKCKCYP
What is the function of this protein?
Reversible blocker of both Shaker B potassium channels (high affinity), and Kv1. 3/KCNA3 potassium channels of human T lymphocytes (low affinity).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 4.4, Toxin Tc30, Toxin To30.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 04 subfamily.
What are the subcellular locations of this protein?
Secreted.