PharMolix/UniProtQA huggingface dataset:
Protein: NUOA_BACFR
Sequence: MNFTLLVVVLLTAIAFVGVVIALSNAISPRSYNAQKFEAYECGIPTRGKSWMQFRVGYYLFAILFLMFDVETVFLFPWAVIARDLGPQGLISILFFLVVLVLGLAYAWKKGALEWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSD_SHEB2
Sequence: MDKVKIALQYMLPKHLLSRLVGKLAAAEAGALTTAAIKWFIKQYKIDMSEAAQSEPEAYKSFNAFFTRALKPGIRPLDMDADIMVHPVDGAVSQLGPIKNGRIFQAKGHHYSSLTLLGDQAEDAKRFEGGDFATIYLAPKDYHRIHMPIKGTLSKMTYVPGELFSVNPLTARNVPGLFARNERVVAIFETELGPLAMVLVGATIVASIETVWAGTVTPPTGKQVFTWEYPTQGPDAITLDKGEEMGRFKLGSTVVMLFAKDAIATFAEGVEAEAVTRMGQAFANLKDVKQAD
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LIPB_CORDI
Sequence: MTAVRDPFFPADQSIRASHNPIEVRELGMMDYQRAWDLQAELNKQRQHDEINDVILVLEHPSIYTAGKRTQPSDRPQNGLPVIDVDRGGRITWHGPGQLVMYPIIKLAEPIDVVDYVRRVEEALIHVIRTHGIPNAGRIDGRSGVWVPGKTPEEHRKVAALGIRIAGGVTMHGLALNCDNTVEFYDYIVPCGISDAGVTTMSQEVGNDVTTQSMTAPLLAALDDAFAGRLVVADHSFASAPDPTKIPRRP
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3890_BORBR
Sequence: MLFLLSPAKKLDYDSPVHVETHTQPLFVDQAAALIKVLKTKSADEIAELMSLSPALAELNAGRYGAWKRSFTQANSRQAVLAFNGDVYEGLQADTLSARQLDWAQDHVVILSGLYGALRPLDLMQPYRLEMGTRLHTPKGKNLYEYWGSGIAEYLNERQAGAKAPVIVNLASEEYFKVVDLKTLKARVVQCVFQDWKNGAWKVISFHAKRARGLMARYAIAHKVARPEGLQGFDSEGYAYDAAASSADKLVFRRKQA
What are the official names of this protein?
UPF0246 protein BB3890.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: HIS3_NITOC
Sequence: MSLGWLEDVAWNKEGLIPAIAQEDRTGQVLMLAWMNREALETTVQSGYAVYWSRSRKRLWRKGEQSGHEQIIKAIHLDCDSDAVLLLVEQKGGMACHTGRHRCFFKRLEKGNWASVEPVLKSPDSIYNNSDE
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOC_POLNA
Sequence: MEFSHPPVSVSQLGETIALVLGGKAKSVKIALGEITVTVAAADYLAAATLLRDAPGCKFEQLLDLCGLDYSEYKNGQYDGLRYCVSSHLLSVSLNQRVRLKVFCPDDDFPVVDSVNGIWNSANWFEREAFDLYGIVFEGHNDLRRILTDYGFIGHPFRKDFPTTGHVEMRYDAEQKRVIYQPVTIEPREMIPRVIREDNYGGLQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HIS3_CENSY
Sequence: MEKKIDEIDFEKAGGIVPVIVQDNNTHEVLTLAYSNRESLELTRKTGLSWFWSRSRSKLWQKGEESGNTQQVKKILVDCDQDALIYLVEPSGPACHTGERNCFHHSLL
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_STRM5
Sequence: MTPTLRRKLEALAERREELERLLAEPDVVADNTRFRDLSREFAQLEPIATALADETRAKADLAAAEGMRADPDLRELADEEIAAAQARLQELEQELALLLVPRDPRDDGNLFLEVRAGTGGDEAAIFAGDLFRMYARYAERQGWKVEIESDNPGEHGGYKEVVARVVGRGAFSRLKFESGTHRVQRVPATESQGRIHTSAATVAIIPEADEVDDIVINPADLRVDTFRSSGAGGQHVNKTESAIRITHVPTGVVVECQTERSQHANRDKAMKRLKAQLLDAERQRQDAAQAESRRLQVGSGDRSQRIRTYNFPQGRITDHRVEGLTLYDLPNILAGDLDPLLQRLSHEHQVDALAQLSAG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S7A14_DANRE
Sequence: MSGLFAKLDPRRVQWGANWFAFRSRVLRTKPVESMLETSGGTGAHGTKLARVLSTVDLVSLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHSISGFMINHIGTLNGLGKGEQSYPDILALVIGILVTVIVALGVKNSVGFNNVLNVINLVVWVFIMIAGLFFVSGSNWDEGRFLPYGWSGVMQGAATCFYAFIGFDIIATTGEEAKSPNTSIPYAITASLVTCLTAYVSVSVILTLMVPYTEIDSDAPLMEMFSLHGFQTAKYIVAIGSIAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSTYTETPAVACVVSGFLSALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPEGDIHGFVNFLSEQNSKRKEGVLAECEKEACSPVSEGDDYGGVPTNTCGAKNLPSLGDNEMLIGKPDKSTYTASHPNYGTVDMSSGIESDETDSAYLLKLKKLLGPRYYTMRIRLGLPGKMDRPTVATGRIVTRCVVLLFILIFCFCSLIIFGSGQIADGQWWAVLLLVVLLLVLTLLVFIIIQQPENPKRLPYMAPCVPFVPASAMLVNVYLMLKLSTITWIRFGVWCFVGVLIYFGYGMWNSTLEITAREEEAHASTYQRYDMGVDDNFAVDDDLYPSGDQGPFQNWGKGGQQKQPQQEQSEPQSDGLDRLDNHRTSSSSSHSRAKSKASKPSPGFEALVVDDDLDDPLE
What is the function of this protein?
May be involved in arginine transport.
What are the official names of this protein?
Probable cationic amino acid transporter, Solute carrier family 7 member 14.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: RL33_YERPA
Sequence: MAKGVREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVLYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PARE_STAEQ
Sequence: MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEVVDNSVDEVLNGYGDAITVTINQDGSISIEDNGRGMPTGIHASGKPTAEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYTQNFKNGGIPATGLVKTGKTKKTGTKVTFKPDSEIFKSTTTFNFDILSERLQESAFLLKDLKITLTDLRSGKEREEIYHYEEGIKEFVSYVNEGKEVLHDVTTFAGHSNGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNEYARRINELKDKDKNLDGNDIREGLTAIISVRIPEELLQFEGQTKSKLGTSEARSAVDSVVSEKLPYYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGKKNKRKDTLLSGKLTPAQSKNTDKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTIGAGVGTDFKIEDSNYNRIIIMTDADTDGAHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKNKKVEYAWTDEELENLQKQLGKGFILQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVAPRREWIEKHVEFGMQEDQSILDNKEVQILENEKYIEEETN
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit B, Topoisomerase IV subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family. ParE type 2 subfamily.
Protein: Y3148_AZOC5
Sequence: MSQTPPPNRLCAVTLDDASIGRSGADVEHERAIAIYDLLEDNRFTPVGDPGEGPYTLHIGLMDNRLVLDIRREKGSEPVVQHHLSLSPLRKVVKDYFLICESYYAAIRTASPTQIEAIDMGRRGLHNEGSTLLQERLKDKVEVDFDTARRLFTLICALHWKG
What are the official names of this protein?
UPF0262 protein AZC_3148.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: GLMM_SALPA
Sequence: MSNRKYFGTDGIRGRVGNAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSASFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKEITCVDSAELGKASRIVDAAGRYIEFCKGTFPNELSLNGLKVVVDCANGATYHIAPNVLRELGATVIAIGCEPNGVNINEEVGATDVRALQARVLVEKADLGIALDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKLQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMVRNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLENDAVKAVTADVEATLGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTAFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: HEMA_I77A6
Sequence: QDLPGNDNSTATLCLGHYAMPNGTLVKTITDDQIEVPNATELVQSSSTGKICNNPHRILDGRDCTLIDALLGDPHCDVFQDETWDLFVERSNAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPASGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTDQEQTNLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGQSGRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNADVLVALENQHTIDLTDSEMNKLFEKTKRQLRENAEDMGNGCFKIYHKCDNACVESIRNGTYDHDVYRDESLNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: PSBA_PINTH
Sequence: MTAIIERRESANLWSRFCDWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENQSANAGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVAGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVESISIGG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS2_MYCSS
Sequence: MAVVTMKQLLDSGTHFGHQTRRWNPKMKRFIFTDRNGIYIIDLQQTLTYIDKAYEFVKETVAHGGSIMFVGTKKQAQESIAEEATRVGMPYVNQRWLGGMLTNFSTVHKRLQRLKELEAMEQTGGFEGRTKKEILMLTREKNKLERSLGGIRDMQKVPSAIWVVDTNKEHLAVAEARKLNIPIIAILDTNCDPDVVDYPIPGNDDAIRSAALLTKVVASAVAEGLQARAGGGNGNKPEAEAAEPLAEWEQELLAGATASPTAAGAAPGTPEADIQTEPTAPQNP
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL24_PYRIL
Sequence: MPFTTSIQPRRQRLSLYTAPLHLRHKLFNAKLSPDLQKKLGVKRLPVRRGDTVMIMRGDFKGVTGKVVKVDLKKVRIYVEGATRTNSKGQTVYYPIHPSKVMIIDIDTSDKIRQKIIQRRKKE
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CYSN_VIBA3
Sequence: MNSAVEAELAELGIEGYLSQHQHKSMLRFLTCGSVDDGKSTLIGRLLHDTKQIYEDQLAAVHSDSQRVGTTGEKPDLALLVDGLQAEREQGITIDVAYRYFSTQKRKFIIADTPGHEQYTRNMATGASTCDLAVILIDARKGVLDQTRRHSFISNLLGLKHFIVAVNKMDLVDYSQDRFEEIRDQYLEFAENLEGETNIQILPVSALEGINVAAPSKELAWFEGPSLLEVLENVDIDQKRSAGEFRFPVQYVNRPNLDFRGFAGTVASGRVSVGDEIKALPSGKTSKVARIVTFDGDLESAQAGLAVTLTLEDEIDISRGDLIVLENAQIESTNHVLADIVWMTEQPLQPGKAYDIKIAGKKTVGQVETVRHQYDINNLSTHAVDELPLNGIGLCEWSLNETVALDKYRESADTGGFIVIDRLTNVTVGAGLIRDRLDSVEQQVGNFSAFELEFNALVRKHFPHWDAKDLSQLLKS
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: LFTR_HAHCH
Sequence: MPALPWLDENLWFPHPDSALKDPNGLLCVGGDLHPARLRLAYENGIFPWFSEDQPILWWSPDPRCIIRHEDLHISRSMRRFLRNSGLTYSFDQHFTLVVQACAAPRSYSNETWITRDMLQAYSDLHQIGVAHSIEVWRESELVGGLYGLAIGRCFFGESMFSKETNASKAAFITLVRQLHAWGYRLIDCQVPNPHLLSLGACQISRKEFLSILEIEVRADFSHPWKMTIDPTGY
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIR13_ARATH
Sequence: MANQIYIISLIFLSVLLYQSTTVLSFRQPFNLAKPCKRFVFYLHNVAYDGDNTDNATSAAIVNPLGLGDFSFGKFVIMDNPVTMDQNMLSEQVARVQGFFFYHGKTKYDTWLSWSVVFNSTQHKGALNIMGENAFMEPTRDLPVVGGTGDFVMTRGIATFMTDLVEGSKYFRVKMDIKLYECYY
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
What are the official names of this protein?
Dirigent protein 13, AtDIR13.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: RL34_ANAMM
Sequence: MKRTFQPSRIVRKRRHGFRARMSTRWGRKILNRRRAKGRCLLCA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DIUX_RHOPR
Sequence: GLDLGLSRGFSGSQAAKHLMGLAAANYAGGP
What is the function of this protein?
Regulation of fluid secretion.  Stimulates primary urine secretion by the Malpighian tubules.  Increases the frequency of contraction in the heart and hindgut.  Causes a dose-dependent stimulation of cAMP levels in the dorsal vessel and hindgut, but not in Malpighian tubules.  Has synergistic effects on urine secretion by Malpighian tubules with serotonin.
What are the official names of this protein?
Diuretic hormone class 2, DH(31), Diuretic peptide, DP, Rhopr-DH31.
What is the protein family that this protein belongs to?
Belongs to the diuretic hormone class 2 family.
What are the subcellular locations of this protein?
Perikaryon. Cell projection, dendrite. Cell projection, axon. Secreted.
Protein: HIS1_BURTA
Sequence: MTAPLTLALSKGRIFEETVPLLAAAGVTVAEDPERSRKLILPTTDPNLRVIVVRATDVPTYVEYGAADFGVAGKDVLLEHGGGGLYQPIDLNIARCRMSVAVPAGFDYANAVRQGARLRVATKYVETAREHFAAKGVHVDLIKLYGSMELAPLVGLADAIVDLVSSGGTLKANNLVEVEEIMPISSRLVVNQAALKLKRAALKPFLDAFERASQGGGA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_RIPO1
Sequence: MALFGFGKKLTLPTPETALPGRRQAMPVPASHYVNGHPLKPPFPSGLETAMFGLGCFWGAERKFWQCEGVYTTAVGYAAGITPNPTYQEVCTGLTGHNEVVLVVFDPKIISYEELLKVFWESHNPTQGMRQGNDVGTQYRSGIYVYSPQHKKAAETSKEVYQKALNQAGYGDITTEILDAPEFYYAEDYHQQYLAKNPNGYCGLGGTNVSCPIGLNV
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: VAL3_ARATH
Sequence: MLSSSSMSSSSLSARFCFNHECFEFKLDHCRPGWRLRSGDFVDLCDRCASAYEQGKFCDVFHQRASGWRCCESCGKRIHCGCIASASAYTLMDAGGIECLACARKKFALGPNFSPSPSFLFQSPISEKFKDLSINWSSSTRSNQISYQPPSCLDPSVLQFDFRNRGGNNEFSQPASKERVTACTMEKKRGMNDMIGKLMSENSKHYRVSPFPNVNVYHPLISLKEGPCGTQLAFPVPITTPIEKTGHSRLDGSNLWHTRNSSPLSRLHNDLNGGADSPFESKSRNVMAHLETPGKYQVVPRFWPKVSYKNQVLQNQSKESESVVTPLFEKILSATDTGKRLVLPKKYAEAFLPQLSHTKGVPLTVQDPMGKEWRFQFRFWPSSKGRIYVLEGVTPFIQTLQLQAGDTVIFSRLDPERKLILGFRKASITQSSDQADPADMHSPFEVKKSAYITKETPGVECSSGKKKSSMMITRSKRQKVEKGDDNLLKLTWEEAQGFLLPPPNLTPSRVVIEDYEFEEYEEAPIIGKPTDVAGSTCTEVEGLLISPTTTKHPRHRDGCTCIICIQSPSGIGPKHDRCCSCAVCDTNKRRRRSLLLRREKKQMEKEDNARKLLEQLNSDNGLHQSANNSENHERHASPLKVQLDLNFKPEKDEESLPGSNKTTKSETLPHDDTVKSSFTSPSSSSAHSQNNKEDEGKLKTTTEIADTTTTSSM
What is the function of this protein?
May be involved in plant development.
What are the official names of this protein?
B3 domain-containing transcription factor VAL3, Protein HIGH-LEVEL EXPRESSION OF SUGAR-INDUCIBLE-LIKE 2, Protein VP1/ABI3-LIKE 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y4083_YERPE
Sequence: MSAIALTVSMLALVAVLGLWIGNWKIYGVGLGIGGVLFGGIIVGHFAQTYQIVLNGDMLHFIQEFGLILFVYTIGIQVGPGFFSSLRVSGLRLNCFAILMVVVGGLVTAIIHKLFAVPLPIILGVFSGAVTNTPALGAAQQILTDLGSPPQLVSQMGMGYAMAYPFGICGILLVMWLIRLFFKINIDREAKAFDSSYGQNRELLQTMNVAVRNPNLHGLSVQDVPLLNSDEVVCSRLKRGDLLMVPMPATVIEIGDYLHLVGQRDALEKVRLVVGEEVDVTLSTAGTALQTARVVVTNEAVLGKKIRDLNLKQKYDVVITRLNRAGIELVASNSASLQFGDILNLVGRPEAIEAVSAIVGNAQQKLQQVQMLPVFIGVGLGVLLGSIPLFVPGFPAALRLGLAGGPLVVALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKSGGDFINTLVNGDGLAWIGYGAMITGIPLLTVGILARMLVKMNYLTLCGMLAGSMTDPPALAFANGLHPTSGAAALSYATVYPLAMFLRIMSPQILAVLFWTL
What are the official names of this protein?
Putative transport protein YPO4083/y4100/YP_3992.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FXL17_XENLA
Sequence: MGHVAPHASKKEHVAPHAAEKDHVAPHASKKEHVAPHAAEKGQVAPYAAGEGQVAPNAAGERPVAPYAAGEGQVAPYAAGEGQVAPYAAGEGQVAPYAAGEGQVAPYAAGEAQVAPHAAGEGRVAPHAAGDGQVEHCTVEDREEGHIGTTEQGHMSHYTSKLEHMAPPSAQTEAVVSYVAGERHAPPDCTVSGPAMCCSAEARQTTPDWTTTGPEISQGTLPGLTVLHVGGTWQTFAAEDEPCVTTLLSPVKPLSSSRKYAPYNLQIPSYSESEPQAHKGLSSETFGPCEPLHINQLPSSLLLKIFSNLSLNERCILASLVCKYWRDLCLDSQFWKQLDLSNRQQIKDNILEEIASRSQNITEINISDCFSVSDQGVCVVALKCPGLVKYTAYRCKQLSDISLIALAAHCPSLQKVHVGNQDKLSDEALIQMGRRCKELKDIHFGQCYKISDEGLIVIAKGCQKLQKIYMQENKLVSDESVKAFAEHCPGLQYVGFMGCSVTSEGVINLTKLKHLSSLDLRHITELDNETVMEIVKQCQHLTSLNLCLNRSINDRCVEVIAKEGRSLKELYLVTCKITDYALIAIGRYSKSIETVDVGWCKEITDYGAKQIAQSSKSIRYLGLMRCDKVNEATVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNASPAT
What is the function of this protein?
Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerization of BTB domain-containing proteins (dimerization quality control, DQC) (PubMed:30190310).  FBXL17 specifically recognizes and binds a conserved degron of non-consecutive residues present at the interface of BTB dimers of aberrant composition: aberrant BTB dimer are then ubiquitinated by the SCF(FBXL17) complex and degraded by the proteasome (By similarity).  The ability of the SCF(FBXL17) complex to eliminate compromised BTB dimers is required for the differentiation and survival of neural crest and neuronal cells (PubMed:30190310).
What are the official names of this protein?
F-box/LRR-repeat protein 17, F-box and leucine-rich repeat protein 17.
What is the protein family that this protein belongs to?
Belongs to the FBXL17 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Present in the cytoplasm and nucleus; more abundant in the cytoplasm.
Protein: TEG7_EHV1B
Sequence: MFKWLMSSLCGIRNSTSPEVYEPIIGGQNPATMLRLQSALAAVNALLPATLTIEDVISSADNTRRLVKAQTLARTYQACQHNIECLSRHRASSDNPNLNAVVTTHMINAKRLSDTCLAALMHLYLSVGAVDATTDTMVDHAIRMTAENSVVMADVAVLEKTLGLDPQATVRAQDLLALNSGVLNSVNAVAEMTDPTDDVEFTQSVHSPLLPRQLSTTEVVGVPSPVKSNLKSKHKPKRKASLVAV
What is the function of this protein?
Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes.
What are the official names of this protein?
Tegument protein UL51 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL51 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host Golgi apparatus.