PharMolix/UniProtQA huggingface dataset:
Protein: PLSX_ECO55
Sequence: MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDAITPLLAKADFEQRSRLQIIPAQSVIASDVRPSQAIRASRGSSMRVALELVKEGRAQACVSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQFAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEANELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKSLTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAARLESVYPAGFELLDGGKSGTLR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MURE_HAEIN
Sequence: MKKLTALFNLPELKNDIELHNMVLDSRKVKAGDLFVAIKGHQVDGNQFIDSALHSGASAVVSETELSSEHLTVAFIGNVPVVKYYQLAHHLSSLADVFYDSPSNNLTLVGVTGTNGKTTISQLLAQWAELLGHRAAVMGTIGNGLFGQIVEAKNTTGSAVEIQSSLSAFKHAGADFTSIEVSSHGLAQHRVEALHFKAAIFTNLTRDHLDYHQSMENYAAAKKRLFTELDTQIKVINADDEIGYQWLTELPDAIAVSMNADFKVGSHQWMKAINIHYHFKGADITFESSWGNGVLHSPLIGAFNVSNLLLVMTTLLSFGYPLENLLATAKSLKGVCGRMEMIQYPNKPTVIVDYAHTPDALEKALIAAREHCQGELWCIFGCGGDRDRGKRPLMAQVAEQFAEKIIVTKDNPRTESQSQIETDIVAGFKNMEKVGIIPDRAQAIQFAIESAVENDVILIAGKGHEHYQIIGSEVVHFSDQEIALDFLK
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_ECOSM
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: TM253_MOUSE
Sequence: MDQNANQPRQERPSVRLEKLQHWARHKQSGRLLVLAVSQVWLAIAMVPFTISVSCLTSACHLVTALPLWPGASGLLTGIITLELRRAPCIWKVRAMMISNTFNLILGFVAVVIEVMKTALGTASMDSSQSTGLLVLELSAEAFTLAGVLVSTYALFLLSQRKPGYFKRSRLQYRELQEGLSEMEEVSGLENGPVVASTGNRTDE
What are the official names of this protein?
Transmembrane protein 253.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VPS29_PONAB
Sequence: MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALEANIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS
What is the function of this protein?
Acts as component of the retromer cargo-selective complex (CSC).  The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.  The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3.  The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling.  The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway.  The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins.  The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5.  Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).  Acts also as component of the retriever complex.  The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1).  In the endosomes, retriever complex drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling.  The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes.  Involved in GLUT1 endosome-to-plasma membrane trafficking; the function is dependent of association with ANKRD27.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 29, Vesicle protein sorting 29.
What is the protein family that this protein belongs to?
Belongs to the VPS29 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Early endosome. Late endosome.
Protein: MPRR_STRLI
Sequence: MELEVRHLRALCAIADAGSLHRAARRLGVAQPTLSTQLTRIEQALGGPLFTRERTGCRPTPLGRTVLGRARPLLTDMNTLVREARAAAAGGDSRLRVGSTASRALAGWLRRLRRPGLEPTLQMDVSANALLRRVTDGQLDVAFVHEVEGCALHIPEDLRLRVLVEREPQFVMLPADHPAAARPVVRLADLADDRWMVDPTVDGEWDGVHRMLRAVGLNPRVLHGDYHTAASLVATGEVVTVCQPSSQSRPDTAVRRLYGDPLGVRLLLAGTRAELDAVFPALEDAYWEAARQSTAYREWLEGGGIRTLPRCPVAATGGGRVSCGRAEGSRSRRPRDVAPPRPIG
What is the function of this protein?
Transcriptional activator of the gene (snpA) for the small neutral protease.
What are the official names of this protein?
Small neutral protease regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: HGPA_HAEIF
Sequence: MTNFRLNVLAYSVMLGLTASVAYAEPTNQPTNQPTNQPTNQPTNQPTNQPTNQPTNQPTNQPTNQPTNQNSNASEQLEQINVSGSTENTDTKAPPKIAETVKTAKKLEKEQAQDVKDLVRYETGITVVEAGRFGNSGFAVRGVEENRVAVQIDGLHQAETISSQGFKELFEGYGNFNNTRNSAEIETLKQVTIRKGADSLKSGSGALGGSVSLDTKDARDYLLNKNYYASYKRGYNTADNQNLNTLTLGGRYKYFDAIAVLTSRKGHELENFGYKNYNDKIQGKTREKADPYRRTQDSALLKIGFQPTENHRFSVVADLYKQTSKGHDFSYTLKPNTQYMTYDEKELRHTNDKVERKNIAFVYENFTETPFWDTLKITYSHQKITTSARTDDYCDGNDKCALAGNPLGMKYNQDNQLVGKDGKSAKYQDINKTQVIKERLPFTKPNGRWRFHKVDWDALKKKYPGVPIYASCLEEDNDPSEFCTYEVKTTKKENTFEINGKRYDLLSEADKNVISDEQRLPTNVSYLFSCDGLNCDKKTILGFKKRRNLLKIFLFEVIEKRCQKYGKTKVKANDQLSGPYLFMPNKKGYQANLWSQRDLTSETKQINLDLTKHLELGKTQHDLSYGGLWSEMEKSMTNLAGDTPLNVKWWAQYPHNCATFLPPSTMTPNAKPTLNPERTSTLCNNVNVFSFLIPVKTKTGALYFINDFRVNNYVAFNLGYRYDRVKYEPEYIPGKTPKIPDDMVTNLYIKTPEFDASKADSDPDELSKKEANAAANIKEIAQPKKFSASSYSFGTTLDPLNWLRLQAKYSKGFRAPTSDEIYFTFKHPDFSIQPNRDLQPETAKTKELSLTVHNDMGYITTSVFDTRYQNFIDLSYQGRRDVHGHSKLIPFHFYQNVNRPNAKVTGFEIASQISLGNITKLFNGFSLSYKYTYQKGRINGNIPMNAIQPRTAVYGVSYVHPDDKYGLDLYISHASAKNAEDTYNMFYKEEGKTDSTIKWRSKSYTTIDLLGYIKPIKNLTLRAGVYNLTNRKYITWDSARSIRPFGTSNMINQDTGLGINRFYAPERNYRMSVQFEF
What is the function of this protein?
Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex of the human host and is required for heme uptake.
What are the official names of this protein?
Hemoglobin and hemoglobin-haptoglobin-binding protein A, Heme-repressible hemoglobin-binding protein, Hgb.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. Hemoglobin/haptoglobin binding protein subfamily.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: VODN_VIOOD
Sequence: GLPVCGETCTLGKCYTAGCSCSWPVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Vodo peptide N.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: TRI45_HUMAN
Sequence: MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFCPQEKAGQCRGYEIYGTINTKEVDPAKCVLQGEDLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRRKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGHPHWSCCGKFNEKSECTWTGGQSAPRSLLRTVAL
What is the function of this protein?
May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.
What are the official names of this protein?
Tripartite motif-containing protein 45, RING finger protein 99.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DPO4_STRPF
Sequence: MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKDPRETGGRGVVSTCNYEARKYGIHSAMSCKEAYERCPKAIFISGNYEKYRTVGDQIRRIFKRYTDVVEPMSIDEAYVDVTNNKLGIKSAVKIAKLIQHDMWKEVGLTCSAGVSYNKFLGKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLAVPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEISKNAKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFDSLSENPAGIRLLGVTMTNLEDKVADISLDL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR8_GNEPA
Sequence: MDTITNLITSIKNAYMVKKQTVRVNATRINENFGRILLQEGFIRNIREHKDGQKFFLIFTLKYRKRGEKIITLKRISRPGWRIYSDFPKIPKVLGGMGIVILFTSQGIMTDREARKKKIGGELLCFVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: S39AC_MACFA
Sequence: MCFQTKLSISWVPLFLLLSRVFSTETDKPSAQDSRGRGSSGQLADLLQVLSAGDHPPHNHSRSLIKTLLEKTGCPRRRNGMQGDCHLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANENTLPQLAATIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTHTLRLSELDQLLNTLWTRSTCIKKDKIHQLQRKQNSIITPDQDYSNFSSSMDEESEDGPISWDQTCFSARQLVEIFLQKSLSPISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLLGLIGGIHGFFLIEKCFILLVSPNDKKSPEDSQAAEMPIGSMTAPNRKCKVISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFIGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMPPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNIKK
What is the function of this protein?
Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane.  The transport activity is temperature dependent.  May play a role in neurulation and neurite extension.  May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis.
What are the official names of this protein?
Zinc transporter ZIP12, Solute carrier family 39 member 12, Zrt- and Irt-like protein 12, ZIP-12.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLT14_MOUSE
Sequence: MRRLTRRLALPIFGVLWITVLLFFWVTKRKLEVPLGPEVQTPKPSDADWDDLWEQFDERRYLNAKKWRVGDDPYKLYAFNQRESERISSNRAVPDTRHKRCSLLVYCTDLPPTSIIITFHNEARSTLLRTIRSVLNRTPMHLIQEIILVDDFSNDPEDCKQLIKLPKVKCLRNNERQGLVRSRMRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIINLDTFNYIESASELRGGFDWSLHFQWEQLSLEQKALRLDPTEPIRTPIIAGGLFVIDKAWFDYLGKYDVDMDIWGGENFEISFRVWMCGGGLEIIPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYAARPFALERPFGNIENRLNLRKNLHCQTFKWNLENVYPELRVPPDSSIQKGNIRQRQKCLESQKQKKQEILRLSPCAKVKGDGAKSQVWAFTYTQQIIQEELCLSVVTLFPGAPVVLALCKNGDERQLWTKTGARIEHIASHLCLDTDMFGDSTEDGKEVVVNPCESSLMSQHWDIVSS
What is the function of this protein?
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.  Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58).  May be involved in O-glycosylation in kidney (By similarity).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 14, Polypeptide GalNAc transferase 14, GalNAc-T14, pp-GaNTase 14, Protein-UDP acetylgalactosaminyltransferase 14, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: LPLA_ECO8A
Sequence: MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITKAFFAHYGERVEAEIISPDKTPDLPNFAEIFARQSSWEWNFGQAPAFSHLLDERFSWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGGLYRADMLQQECEALLVDFPDQEKELRELSTWIAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLTK_ECOLI
Sequence: MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVMRLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKRRTA
What is the function of this protein?
(Microbial infection) Probably transports the toxic C-terminal region of CdiA from P. luminescens strain TTO1 across the inner membrane to the cytoplasm, where CdiA has a toxic effect.  Toxin transport is strain-specific, mutations in this gene do not confer resistance to several other tested CdiA toxins.
What are the official names of this protein?
Glutamate/aspartate import permease protein GltK.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLSY_HYDS0
Sequence: MGFIIGFLLSVFGYLLGSILFAKIVASYKGIDITSVGSKSAGATNVTRTLGKKYGALVFLLDAFKGFLIAILDRFYIDPSSLWFGIVMVSPVIGHIYSYRSDFKGGKGVATAFGVVFGISPLLALKMFLVWAFVFYLFRYVSLASITSVLVGYFLFLEGDFSTSQKLGATMIAFLILYKHKDNVFRLLRKEEHKFK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEND_DESHY
Sequence: MTNYIAALVDELYQLGVREAVISPGSRSTPLSVLFCEYGFQVYVGIDERSAGFFALGIAKEKERPVVLVCSSGSAVAHYFPAIVEAKHSHVPLIVLTADRPPELRQVGAPQTIDQIKFYHDYAKYFEELALPEEREGMYRYVRGVMRKAYVSSLDQGYGVAHINIPLREPLSPDLDGVDFTAGRLDYPFAWKTGEKGLTMDSSVFQDKKGIIICGGDPYADYHREVLELAERLKAPLLADPLANFRNDDHPLIMDCYDAFLKSDAVKVELKPEFIIHFGQTPVSKRLQNFTAMHQDVLYFQVNDYFQYRDPSLSISRYLVASPKAFARSVKVHNTDDGYSGRWQHYQARMRRRLNLAQDEEELFEGKLVQKLQDSLPEGSRLFVANSMAIRDVDYFLEARRQRIKVLGNRGANGIDGTVSTALGVATSGHPTVLLTGDLAFFHDLNGLLIGKNHGLNLIIVLLNNNGGAIFKYLPQSENKYFELLFMTPHGMDFSGLKTLYDLTYYEPVDYESFAQNFQEALTLSGVKVLNVKIDARLSKELHDRLTNLD
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: SIPA1_HUMAN
Sequence: MPMWAGGVGSPRRGMAPASTDDLFARKLRQPARPPLTPHTFEPRPVRGPLLRSGSDAGEARPPTPASPRARAHSHEEASRPAATSTRLFTDPLALLGLPAEEPEPAFPPVLEPRWFAHYDVQSLLFDWAPRSQGMGSHSEASSGTLASAEDQAASSDLLHGAPGFVCELGGEGELGLGGPASPPVPPALPNAAVSILEEPQNRTSAYSLEHADLGAGYYRKYFYGKEHQNFFGMDESLGPVAVSLRREEKEGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPPGPPRGLSPRKLLEHVAPQLSPSCLRLGSASPKVPRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAFMQFLTLLGDVVRLKGFESYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQLLRKRHIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRTQDTPAFGPALPAGGGPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDLATNEVTTTSLDSASRFGLPSLGGRRRAAPRGPGAELQAAGSLVWGVRAAPGARVAAGAQASGPEGIEVPCLLGISAEALVLVAPRDGRVVFNCACRDVLAWTFSEQQLDLYHGRGEAITLRFDGSPGQAVGEVVARLQLVSRGCETRELALPRDGQGRLGFEVDAEGFVTHVERFTFAETAGLRPGARLLRVCGQTLPSLRPEAAAQLLRSAPKVCVTVLPPDESGRPRRSFSELYTLSLQEPSRRGAPDPVQDEVQGVTLLPTTKQLLHLCLQDGGSPPGPGDLAEERTEFLHSQNSLSPRSSLSDEAPVLPNTTPDLLLATTAKPSVPSADSETPLTQDRPGSPSGSEDKGNPAPELRASFLPRTLSLRNSISRIMSEAGSGTLEDEWQAISEIASTCNTILESLSREGQPIPESGDPKGTPKSDAEPEPGNLSEKVSHLESMLRKLQEDLQKEKADRAALEEEVRSLRHNNRRLQAESESAATRLLLASKQLGSPTADLA
What is the function of this protein?
GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state (PubMed:9346962).  Affects cell cycle progression (By similarity).
What are the official names of this protein?
Signal-induced proliferation-associated protein 1, Sipa-1, GTPase-activating protein Spa-1, p130 SPA-1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Endomembrane system; Peripheral membrane protein. Note=Mostly localized in the perinuclear membraneous region.
Protein: DNAK_BRECH
Sequence: MSRVIGIDLGTTNSCVAVMEGGEPVVIANPEGNRTTPSVVAFKNGEKIVGEAAKRQAITNPDNTVISIKRHMGTSHKETLEGNEYTPQQISAMILQKLKSDAEAYLGESVTQAVITVPAYFNDSQRQATKDAGKIAGLEVLRIVNEPTAAALAYGMEKSEDQTVLVFDLGGGTFDVSILELSEGFFEVKATSGDNKLGGDDFDQVVMDYLVSEFKKEHGIDLSKDRMAQQRLKDAAEKAKKDLSGVLTTTISLPFITADATGPKHLEMNLTRAKFEELSSNLVERTMGPTRQALNDAGLTPNEIDKVILVGGSTRIPAVQEAIKKFTGKEPHKGVNPDEVVALGAAVQAGVLTGDVKDVVLLDVTPLSLGIETLGGVFTKLIDRNTTIPTSKSQVFSTAADNQPGVEIHVLQGERQMAADNKTLGRFNLNDIPPAPRGVPQIEVSFDIDANGIVNVRAKDLGTGKEQRITITASSGLSDEEIDRMVKEAELNAEADKQRKEQVEIRNEADQLVFTTEKTLKEVEGKVDQAEIDRANAAKDKVKKALEGGSIDEIKSAKDELSEIVQQISVKLYEQAAQAAGAAQGGAEGSAEPKKDNVVDADYEVVDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PHOB_PSEAE
Sequence: MVGKTILIVDDEAPIREMIAVALEMAGYECLEAENTQQAHAVIVDRKPDLILLDWMLPGTSGIELARRLKRDELTVDIPIIMLTAKGEEDNKIQGLEVGADDYITKPFSPRELVARLKAVLRRTGPGDSEAPIEVGGLLLDPISHRVTIDGKPAEMGPTEYRLLQFFMTHQERAYTRGQLLDQVWGGNVYVEERTVDVHIRRLRKALGEVYENLVQTVRGTGYRFSTKS
What is the function of this protein?
This protein is a positive regulator for the phosphate regulon.  Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.
What are the official names of this protein?
Phosphate regulon transcriptional regulatory protein PhoB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_STRSV
Sequence: MIKGHGIDIEELVAIERAYLKNARFAKKVLTEAELSRFEELSGKRKIEFLAGRWAAKEAFSKAWGTGIGKLRFQDLEILNDRQGAPYFSRSPFTGKVWISLSHAAGLVTASVILEENDES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_BURMS
Sequence: MAITMRQMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMYNDALKYVRQLAANRGTILFVGTKRQSRDTIAQEALRAGMPYVNARWLGGMLTNFKTLKVSIKRLKDMEAAVEAGELEKMSKKEALLFEREIAKLQKSIGGVKDMGGIPDAIFVVDVGYHKIAVTEANKLGVPVIAVVDTNHSPEGVDYVIPGNDDSSKAVALYAQGVADAILEGRANAVNEVVQAVRGDDEYVEENA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SDHF3_ASHGO
Sequence: MRTTNHLYRTVHRQGKPLLPPLHLYRRILRAHRTFPPAQRALGDEYVKSEFKLHKNIDNPVHIIGFLASWQDYFHMISTNSWAEGTLSKSLVDQMSSEQIVQLYELMKETKQLGGASAESGSSLS
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  May act together with SDHAF1.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 3, mitochondrial, SDH assembly factor 3, SDHAF3.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ARGB_BRUSI
Sequence: MTTLENPEMQAQLLSAALPYMQRYENKHVVVKYGGHAMGNPELGKAFARDVALLKQSGVNPIVVHGGGPQIQAMLTKLGIESRFEGGLRVTDEKTVEVVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAQKAHKTVIDPDSNIEKVLDLGFVGEPAEVDRTLLDLLARSEMIPVIAPVAPGRDGHTYNINADTFAGAIAGALAATRLLFLTDVPGVLDKDKKLIKELSVADAQALIRDGTISGGMIPKVETCIDAIRRGVEGVVILNGKTPHSVLLELFTEHGAGTLIVP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DB125_HUMAN
Sequence: MNILMLTFIICGLLTRVTKGSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISIISHEYTRRPAFPVIHLEDITLDYSDVDSFTGSPVSMLNDLITFDTTKFGETMTPETNTPETTMPPSEATTPETTMPPSETATSETMPPPSQTALTHN
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 125, Beta-defensin 25, DEFB-25, Defensin, beta 125.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.