PharMolix/UniProtQA huggingface dataset:
Protein: UPPS_SHIFL
Sequence: MMLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEKVQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGTEPGDETA
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: CYAY_POLSJ
Sequence: MTDLEYQDLAESALTAIETACDRINDETDADIDNQRTGGMITLTFSNRSQIIINLQKPLQEIWMAAKAGGFHYKFRGNQWLDTKDSSEFFTGLSRYASEQAGQPLVFNAPVPVTGK
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: DBHA_ECOLI
Sequence: MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQLVGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU-alpha, HU-2, NS2.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Scattered throughout the nucleoid (PubMed:21903814).
Protein: FDHD_MYCPA
Sequence: MQVTSRRRVTHLTAGQAIARPETLVVEEPLEIRVGGAAVTVTMRTPGSDFELAQGFLLTEGIIGAREDVHSIRYCAGCGEDGANSYNVLDVTLAAGLGRPELDVTRNFYTTSSCGVCGKASLEAVRSVSRFSPAADPATVAAATLQAMPHQLRSAQKVFDSTGGLHAAALFRADGTMLVVREDVGRHNAVDKVIGWALEQQRLPLRATVLLVSGRASFELAQKTVMAGIPVLAAVSAPSSLAVSLAEESGVTLVAFLREDSMNIYTRADRIG
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR14_GUIAB
Sequence: MAKKSLIQREKKRQKLEQKYHLIRRSSKKEISKVRSLSDKWEIYGKLQSPPRNSAPTRLHRRCFSTGRPRANYRDFGLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YSP4_CAEEL
Sequence: MLSLTAHLVLISTIIVKCSAFSKKPSERAKPAAVKKAVEDKQPVKVTAFEQASLNEDKAEAMSNIEPSPKISNSTVPTAPTPKKEKKVVATTKKTERSVAQGPPLVSEHIKDEKKMPSVHKPIRKGSIYANELLTEKPLTDTEPELHPDNHVVKAKSPKPVARTPTARHRNALKPGKINDKSDDTLHDAPSIQKVGGPSYEDAASVNEKEKDVNPK
What are the official names of this protein?
Uncharacterized protein B0034.4.
Protein: IML2_CANGA
Sequence: MFKVFGALSGKGSSDSNGNSTRSSINEKRTKLILKEANDFEIALRAMDYVLDDRTEEGLALLRENEKVNGQNQTITVLARGVIEFLQATLSFEMEEIKNASNTLAKAEQLSWKSRTEAQKSGIRNSSIYPPGTVYAVTYTESCLLHALLMLFTESMMDAAKALLKLRKAYSMLHEIMEVVKKSELSRKVSSSSAVSIQSNGSFVSEEATFVSADIPYQLSETESNDPELWAFAEKIYKMRKLRLSGAHIGNTPAISRLRSGLGLSASNKSEELANSEQSVLSDEAAERQATIDEFIHSGVNLCYGILQVVLSLIPPAIGAVLSIVGFRGSREEGLRLIWKATKDRNVHGCIGLLGLMFYYDGPFQFTDVDFDIPPALSNTKTSDSDTDRDGSISIDEMDGHALLHPGPILEEALLHARALFPNSALWLLNEARMLSSRGRLPEAIELLDSIDVESIHMRQVKGLLVFDKAITLVHMQEYERAATNLLSLLKISDWSHAFYTYFAGCCYLENWRMAQMGFIKDDKLEFYREKAEELIFSAPKLLGKKTFKSKNLPLDRFMLRKVEQFKATQKKLGVKNILDAIGTSPIREITYFYNGYNRMSKSDLEIAQKMLTSYHNPAIDQHDPDQELIKNLLLSLTMRRLGDVESGVKLLDEKVLPSIYYMQNGKVKYIKKTEDPWAYPTALYERALFTWKLDGVDNLSECRHWLVTAQNYAGDYELSTRVGMKIKAALDRVEESLQHGTA
What is the function of this protein?
Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins.  Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
What are the official names of this protein?
Inclusion body clearance protein IML2.
What is the protein family that this protein belongs to?
Belongs to the IML2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized exclusively in cytoplasmic inclusion bodies under protein folding stress conditions.
Protein: ENO_POLAQ
Sequence: MSAIVDIIGREVLDSRGNPTVECDVLLESGVMGRAAVPSGASTGSREAIELRDGDKSRYLGKGVLKAVQNINVEIAETILGLDASEQAFLDHTLIELDGTHNKARLGANATLAVSMAVARAAAEEAGLPLYRYFGGSGGMQLPVPMMNIVNGGAHANNSLDIQEFMVMPVGAENFRDALRCGAEIFHELKKILAAQGMPTTVGDEGGFAPNFKSNHECLQIIMKAIEGAGYQAGEDVLLALDCAASEFYKDGKYHLSGEGLQLTSSEFSDYLGNLADQFPIVSIEDGMHESDWDGWADITQKLGKKIQLVGDDLFVTNTRILKEGIDKGIANSILIKINQIGTLTETFAAIEMAKRANYTAVISHRSGETEDSTIADIAVGTNAGQIKTGSLSRSDRIAKYNQLLRIEEDLGDVATYPGKSVFYNLKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: GAL1_PYRFU
Sequence: MSKITVKSPGRVNLIGEHTDYTYGYVMPMAIDLYTIITAEKYDKVQLYSEHFNEEKTFTLDNLTKEGSWIDYVKGVLWVLIQEGYKIGGLKGKITGDLPLGAGLSSSASFEVGILEVLNQLYNLNIDPLKKALLAKKAENEFVGVPCGILDQFAVVFGKKDNVIFLDTQTLQYEYIPFPKDVSVLVFYTGVKRELASSEYAERKRIAEESLRILGKESSKEVTEKDLGKLPPLHRKFFSYIVRENARVLEVRDALKEGDIEKVGKILTTAHWDLAENYRVSCEELDFFVKKAMELGAYGARLTGAGFGGSAIALVDKDKAKTIGDAILREYLAKFSWKAKYFVVKPSDGVGV
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).  Is very specific for its substrate, since it is not able to use D-glucose, D-fructose, D-mannose, 2-deoxy-D-glucose, and D-glucosamine as substrates.
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_PYRAR
Sequence: MDKEYLALLERAYTLVAPKAQRRTEIPKIQVENMPRKTIIPNFGAIAKRLNRDIYFMAKFFQKELAVPGTVEGDVFTLHGEKSPKVVEAVYERFIRYYVVCPVCNSIDTELRKEGRVFVMKCLACGASTPVKPL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: PPNP_AZOVD
Sequence: MFKVNEYFDGTVKSIAFGTSQGPATIGVMASGEYEFGTSQLEIMHVIAGALTVKLPGSEQWETFEAGSQFTVPANSKFQLKVATDTAYLCEYR
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: PSBK_ATRBE
Sequence: MLNTFSLIGICLNSTLYSSSFFFGKLPEAYAFLNPIVDIMPVIPLFFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HBOH_ACIAC
Sequence: MTVFKTAPLLIAALAASSCGGGGSGAAVDYDFNVRPSYLNDLRQASYDGAGNDLLTGGLGRSGLQDDSPPGYAGSQPTAEELRRNAIYVNYRALVDTTSEGGYGRLYGPNVDAQGRATSGEGMVAGTEAIAYSDDGSGRRNVTLMVQVPDAFDRTRPCIITATSSGSRGIYGGIPTGEWGLKRGCAVAYTDKGTGAAPHDLQADTVALIDGTRTSATLAGTRAAFDAGLSAADLAAFNGATPQRLAFKHAHSGQNPEKDWGLSTLQAVEFAFYVLNERFGDRSPGGQALRTFTPANTTVIASSLSNGGGAAIAAAEQDTRGLIDGVAVSEPSVQMPANAGVTVQRGGRTVAVNGLPLIDYTTQAHLYQACAALAPSLASTPFAAAFAVRFADPAFPVAANRCAGLKARGLLSAATTAAQAEEALARLTAYGWEPESGALHASLAAFEVAPSIAVTYANALSRASVQDRLCGYSFATTSAIGAVQPTPAAVTNTLFATGNGIPPTAGVQLVNDRSRGVPVRDLFSSNAAGVPTWNLEGALCLRSLVTGTDAAARRLQSGLDETRRTGNLQGKPAIIVHGRDDALIPVNHTSRPYAALNRRVEGAASRLSYIEVTNAQHFDAFIGLPATLPGYDSRYIPLHLYLNRALDAMYAHLVNGEPLPASQVVRTVPRGGTPGSAPAITAANVPPIAAMPVAADAVAITSGAIAVPD
What is the function of this protein?
Participates in the degradation of poly-3-hydroxybutyrate (PHB).  It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
What are the official names of this protein?
D-(-)-3-hydroxybutyrate oligomer hydrolase, 3HB-oligomer hydrolase, 3HBOH.
What is the protein family that this protein belongs to?
Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_CHRVO
Sequence: MPTINQLVRKGRVAITAKSKVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTAGVKDRKQARSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DNLI2_KORCO
Sequence: MNFIDVAKIYEKIEATTGRLEMIDYLKNLFLSTPPEILDKIVYLTLGNIAASFEGIELGVGEKLFLRALSLATGIPQERLEEEYPKLGDIGKLAEWAVSKKAAQSFFTEDLTVERVFDTLSKVARATGEGAQDLKVRLIAGILSDAKPLEARYIARIVTEKLRLGVRDMTVLDALSEAFLKGRAYRDKLERKYNIYPDIGKIAKVVAEKGIKGLDEITITLGIPVRPMLAQRLRSAEEIMEKIGPRIFAEFKYDGERMQIHVWKDGKVKIFSRRLEDITEPYPDVREYVSKAVEGHEVVLDCETVAINPDTGEILPFQELMHRRRKYGVEEAMKTYPTVTYAFDLLYLDGRELLDEQLDDRRKILKEILKENEKARLVQYEEIDGNVEELERFFEHAVEMGTEGLVVKDPKSIYQAGVRGWSWIKLKRSYISKMIEPVDLVVVGAFWGKGKRAGTYGALLMAAYSPEEDVFKTVCKMGSGFTDEELARMPKLLEDYKIDHKHPSVISNIEADVYFVPVKVAQVLGDEITLSPTHTCGWNKVRKNAGLAIRFPRFMGWRDDKGPQDATTEEEIIEMYKEQLKVVEVEETKSEEEA
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase 2, Polydeoxyribonucleotide synthase [ATP] 2.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: SLU7_BOVIN
Sequence: MSAAAVDAANAAPLSGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSKRPTLKHQRPQPEKQKQYSSSGEWYKRGVKENSITTKYRKGACENCGAMTHKKKDCFERPRRVGAKFTGTNIAPDEHVQPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQTEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKYEEDVKINNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIANSEECIINDATGEESVKKPQTLMEIHQEKLKEEKKKKKKKKRKHRKSSSESDDEEKKHEKLKKALNAEEARLLHVKEIMQIDERKRPYNSIYETREPTEEEMEAYRMKRQRPDDPMASFLGQ
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome.  Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron.  Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region.  May be involved in the activation of proximal AG.  Probably also involved in alternative splicing regulation.
What are the official names of this protein?
Pre-mRNA-splicing factor SLU7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing. Translocates from the nucleus to the cytoplasm after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.
Protein: MUTS2_STRP2
Sequence: MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIKQAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASRELQSFYANLENVSLEELAFWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHDSESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTVYIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRAKVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGKTIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNIVDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYGIETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQDNDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKAREQAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAKKKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKAVKKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTGVIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: PEBA_PROM4
Sequence: MFDPYLDELNKLLIVNHGEILLVPDGLQECYSKKQDAVIRSWLWSVPGFRRWRVTRMDVGDKLQVFNSVAYPDYLNEQPIMGIDLLWFGIKNKLVAVLDFQPLVQEKSYFDRYYQGLKSLKARYSDFNSKDNVRAYDLSNYFSPWVLLCKGDLFQASSSLPFVFSEFLNAYFDISNNFKKYNSRIEPNRVKELQISYDIYSSAHDPAHGLFKSYFGKQWSERFLKEFLFPHSIAKDKT
What is the function of this protein?
Catalyzes the two-electron reduction of biliverdin IX-alpha at the C15 methine bridge.
What are the official names of this protein?
15,16-dihydrobiliverdin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: YECA_ECOLI
Sequence: MKTGPLNESELEWLDDILTKYNTDHAILDVAELDGLLTAVLSSPQEIEPEQWLVAVWGGADYVPRWASEKEMTRFMNLAFQHMADTAERLNEFPEQFEPLFGLREVDGSELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFERVEKMSPEAFEESVDAIRLAALDLHAYWMAHPQEKAVQQPIKAEEKPGRNDPCPCGSGKKFKQCCLH
What are the official names of this protein?
Uncharacterized protein YecA.
Protein: DEF_HYDCU
Sequence: MDKLDIVLYPDEGLREVCKPVPEMTDELDKLIDEMFYTMYDAPGIGLAAPQVAVQQRLIVVDISETKDEPIALLNPEIIKTAGKITWEEGCLSIPGIYAKVDRPSDILVRGMDRDGKTIEFEANELLAVCIQHEIDHLNGKLFIDHLSGLKRTRAIQKFKKEMAEQANS
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: URED_PSYIN
Sequence: MLSTVITKPPITAKPKNQWLAHLMLEFSDTPVGTQLTRTKRKGPLSVQKAFYPEGPDCAHIYLLHPPAGIVSGDELRIGIDVKKNAHLLFTTPGAGRFYRAREDLTIGDSQQTQITQFDLEAQAKCENFPQETIVYEGADGFNSVDINLTSTSVYLGWDITCLGLPNSDQTFIKGKYCQLNRLFCDAKLIYHDRISLSPSNNLLAHPAGLAGNTVFATFLAYAPILHNNPEHSNKPQQHKALVMQIRAKITAESAQEKVSITEINGLLVIRYLGHHAQECKQLFISLWQLLRPLLLNKTAVQPRIWHT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHI12_ORYSJ
Sequence: MRALAVVAMVATAFLAAAVHAEQCGSQAGGAVCPNCLCCSQFGWCGSTSDYCGAGCQSQCSAAGCGGGGPTPPSGSGGSGVASIVSRSLFDQMLLHRNDAACPASNFYTYDAFVAAASAFPGFAAAGGDADTNKREVAAFLAQTSHETTGGWATAPDGPYAWGYCFKEENGGAAGPDYCQQSAQWPCAAGKKYYGRGPIQLSYNFNYGPAGQAIGADLLGDPDLVASDATVSFDTAFWFWMTPQSPKPSCHAVATGQWTPSADDQAAGRVPGYGVITNIINGGLECGHGEDDRVADRIGFYKRYCDILGVSYDANLDCYSQRPFGS
What is the function of this protein?
Hydrolyzes chitin and plays a role in defense against fungal pathogens containing chitin.  Its overexpression confers enhanced resistance to sheath blight pathogen (R. solani).
What are the official names of this protein?
Chitinase 12, Basic endochitinase 2, Pathogenesis related (PR)-3 chitinase 12.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: B9D2_HUMAN
Sequence: MAEVHVIGQIIGASGFSESSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQIGDMAYWSHPIDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLACPTWRPLGSWREQLARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFDRYGVEC
What is the function of this protein?
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.
What are the official names of this protein?
B9 domain-containing protein 2, MKS1-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the B9D family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Nucleus.
Protein: 50510_ASFM2
Sequence: MFSLQELCRKNIYILPYPLGEHVLQQLGLYWKGYGSLQRIGDDHVLLQQDLIFSINEALRMAGEEGNNEVVKLLLLWEGNLHYAIIGALEGDRYDLIHKYYGQIGDCHKILPLIQDPQIFEKCHELSTSCNIRCLLEHAVKHNMLSILQKHKDQIRFHLALTQILFELACHERKNDIIRWIGYSLHIYQLETIFDVAFAHKNLSLYVLGYELLMHKVNTEAANIDLPNLLSYHLRTAAAGGLLHFMFETLKHGGYVDKAVLSAAISYKHRKVVAHFIHQVPRKTVEKLLLHAVQTRAPKKTLNLLLSSLNYSVHPITKQLVRNVVDYRSTLIVKLLLMRRKRKLNLVDAVLARLVRYSTYTDTVKFMGEFSVSPEKVIKMAARESRTFMIEMISKAVWKNHPQTMIHHLKQLADTMKPQSGKDLIIYTIHYIYQSSNLLVAEEEKNIFKLAKFYANHNSVNRFKQICEDYYTLDVDTRFKTLILECFEIAVQKNYPRIATIVDDFIRFLFYKGDITEEEISEAYSLKNAELYVDLKWLQQEEN
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-10R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: RUVV_VACCA
Sequence: METLTSSSQSLISSPMSKKDYSSEIICAFDIGAKNPARTVLEVKDNSVRVLDISKLDWSSDWERHIAKDLSQYEYTTVLLERQPRRSPYVKFIYFIKGFLYHTSAAKVICVSPVMSGNSYRDRKKRSVEAFLDWMDTFGLRDSVPDRRKLDDVADSFNLAMRYVLDKWNTNYTPYNRCKSRNYIKKM
What is the function of this protein?
Nuclease that specifically cleaves and resolves four-way DNA Holliday junctions into linear duplex products.
What are the official names of this protein?
Holliday junction resolvase.
What is the protein family that this protein belongs to?
Belongs to the RuvC family. Poxviruses-type subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: TENAE_ARATH
Sequence: MEKRGVIDTWIDKHRSIYTAATRHAFVVSIRDGSVDLSSFRTWLGQDYLFVRRFVPFVASVLIRACKDSGESSDMEVVLGGIASLNDEIEWFKREGSKWDVDFSTVVPQRANQEYGRFLEDLMSSEVKYPVIMTAFWAIEAVYQESFAHCLEDGNKTPVELTGACHRWGNDGFKQYCSSVKNIAERCLENASGEVLGEAEDVLVRVLELEVAFWEMSRGGQ
What is the function of this protein?
Involved in thiamine salvage by hydrolyzing the thiamine breakdown product 4-amino-5-aminomethyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) (PubMed:25014715).  Has a high formylamino-HMP amidohydrolase activity (PubMed:25014715).  No activity with other thiamine degradation products such as thiamine mono- or diphosphate, oxothiamine, oxythiamine, thiamine disulfide, desthiothiamine or thiochrome as substrates (PubMed:25014715).  Does not display thiaminase II activity, as it is unable to hydrolyze thiamine (PubMed:25014715).  Is able to carry out two successive steps in the salvage of thiamine breakdown product, whereas two separate enzymes are required in Bacillus species (Probable).  May also serve a damage pre-emption function by hydrolyzing products that would otherwise do harm (Probable).
What are the official names of this protein?
Bifunctional TENA-E protein, Aminopyrimidine aminohydrolase, Formylaminopyrimidine amidohydrolase, Formylaminopyrimidine deformylase, Seed maturation protein PM36 homolog.
What is the protein family that this protein belongs to?
Belongs to the thiaminase-2 family.
Protein: PUS10_CENSY
Sequence: MRPERGYVLCDPCLGRLFGSGNILHCEKRGRIIRGKGRDRPSECHICKGLCPSLEESCGPSLWGAAAYEFETFVVGVRLKSSMAERDDEVRSRCRLAGAAALRAYVAAMLSSYLGAMTGASVDHGAPELSITADLRDNTAEFHPRPVVLSGRYTKSVRGLSQKGAPCGGCAGEGCTSCGMLGVDTGGSVEGVISGHACGTYSARRASFTWVGGEDQESLVGGRGRPFVAQLVQPHRRGLVHPATVRLGGVVLHGLREVRSMPQLPVRFRSKVRLAVSAKGEISDDTLGRLADLGGSTLAVYEGRRRVERAIHSASHSRTGPGSFELHMEVDGGVPFKRFVSGETVFPNLSDLLGTVCSCGGFDFEEITVERGGHPGARGGTRRRPRKGPARPAGGRDRPRKT
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase Pus10, tRNA pseudouridine 54/55 synthase, Psi54/55 synthase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase Pus10 family.
Protein: RNC_ZYMMO
Sequence: MADKRFFGTKTFPNQEKALKAKIMNNDAFISWIEKNLGHRPKDPALFLRAMTHPSHGNSDYQRLEFLGDRVLGLVIANWLYDLFPREPEGKLSRRLNSLVSGASCASIARIVGLPQWLRLGKQARDDGAAASDNVLGDVMEAMIGAIFLESGIEAAGKLIHKYWAPLVTGQESAPKHPKSALQEWAAAHNRRPPVYEIVSRTGPQHNPCFTIQVSIAGVGEASAEGSSKQEAQTAAAQALLDILAQ
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.