PharMolix/UniProtQA huggingface dataset:
Protein: H2AZ_COCIM
Sequence: MPGGKGKSVGGKGAPKDASGKTQRSHSAKAGLQFPCGRIKRFLKNNTQNKMRVGAKAAVYVTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAFGGVLPRINRALLLKVEQKKKSKIEA
What is the function of this protein?
Variant histone H2A which can replace H2A in some nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received.  Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins.  Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
Histone H2A.Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: KCY_BURO1
Sequence: MKSTRPFHPTPVITIDGPTASGKGTVAALVAAHLGFHLLDSGALYRLAALASVRYGIAAEDIDALVKLIDDLHITFREGCAQLDGVDVSNDIRAEAVGNRASAIAVHGPVRTALVARQRAFRKTPGLVADGRDMGTVIFPDAVLKVFLTASAEARATRRHKQLMQKGFSANIDDLLRDLRERDARDSNRAAAPLKPAADAKLLDTSALSVDEAVDQVLQWYRALGQPA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
Protein: LEF4_NPVOP
Sequence: MGADVLIEQEISYTINFSQDLLYLILDSYIKKRCAAPAERYTDLYDANNVRTRQTADSAVSVHKTNLRDERFVHWLRSSNALVPLVRRENRETAVPHDRVSRHIASLIETTVYKLDGVDVKFEHVYMQSGPADRYESTAAHKIAALKTALLGVDCARPSQNLQLGSDAVLARVRLELEFEGAAPAAASLDAFCELVVQMETLADHHNIAPCLPYTTLLDSATPRRFTREQRIAYGAQAPDSTGVKKWAFKLDGVRGRGAFRRGYCLVQTDDMQLHAACISSPFGLNNVVTFQCEVVADKIFVTDLLQVFRYKYNNRTQYECNLHDAYPINADVAVECLNRLHCAVGSVPWPGLGELRFQQFFDPPLAPTHYTTIPIDGYIVLDEQLQYAKYKWLPTVELEYDAPSGALHSIDGPLLGKTVVADLQLKHGAVYECAITDNAINVLKCRPDRIVPSKVC
What is the function of this protein?
Required for late and very late gene expression.
What are the official names of this protein?
Late expression factor 4.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae LEF-4 family.
Protein: RL19_CERS4
Sequence: MNLIAQLEAEQIAALGKTIPDFKAGDTVRVGYKVTEGTRSRVQNYEGVVIGRKGGNTISASFTVRKISFGEGVERVFPLYSTNIDSIEVVRRGRVRRAKLYYLRSRRGKSARIAEVTNYKEKSE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: YL511_MIMIV
Sequence: MFIDKVTNKVNKSVDKTVLKTISKAKEYLSKGGLSLALSANKYEKLVPYNLWYNHELYQITNYTQNNQNMRIRFYNEIMLSPIVSYNEHDLSKIKTLVPNMSLYQPFYPETFYSVWEFLQSEYINQNAMNFLFIGKENKLGSVESLMIYNELYKNNYLNNTYTVWISDNESHDIFSNSYLLKLPKHNYLKQAFKINFLTNTNQLNVYDTIIIDAISQFDDIFDWSKEETDLHANLFYLFTSLKHLKKNTGSILFKFSMMSSQSWFYLFDILFGCFKEYEFFRPKCINPFNSEIYLYLNKFTGNIPKNNILNSILTNLYRQNVTKLFHLNLHHIDINPIFQKYLISRNKWIDNIIDYIDESPQQNNVCYVTKWHNKNNLLQIKDTTNYLDQNNDKYKLSNNSHPKIKSISHNFLLDNNHFKNLLQKRASLNFYKRVMDTRPSRIFLDMSMVHDFSNEYYVTWDYITGTLDFYKNIKNDLKKQYNGEMITTAWIKLYEILNEFPDIIPKKESVKSFHLCEAPGAFVSATHHYMYSLGCELDWYAQTLNPMYENKALDDHYGLMSLYPDKWLFGSKNNNTGDITSSEIIKSYASNKQLSNIDFMTGDAGIYCRPNCLNEQETVMAKINMGQIVCILACLSKGRSAVFKTFLPLTEPLNISLLNLLSSIFEELIFYKPGASNGSNSEIYIVLKSYKGISSSELEMLYLMLDDPKITSTSFITDVICKNFFRSYIKIVSNLIDKQINCLQRNFYYYYNIGELYDLKKNNIYSEYYDEWFNKNKVVYLENTLFS
What are the official names of this protein?
Uncharacterized protein L511.
Protein: MSCL_GEOSW
Sequence: MWKEFKEFAMRGNVVDLAVGVIIGGAFGKIVSSLVNDILMPLVGLLLGGVDFSGLSWKFGKAVVKYGMFIQTVVDFFIISFSIFVFVKVLNKLYWHNKKEEEIKDTAPTLTKEEELLMEIRDLLKQQRETR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMA_BUCAI
Sequence: MPKNFKKHLPLKKYGQNFLINKDTIKNIIKIIDPKTTETLVEIGPGLAALTKPMCELLEELIVIEIDQDLLFLLKKRSFYSKLIVFYQNALNFNFLNLFHKKKQLIRIFGNLPYNISTSLIIFLFKQIKVIQDMNFMLQKEVAERLISTPGNKSYGRLSIISQYYCDIKILLNVSPEDFRPIPKVHSVFINLKPHTNSPYFVYNVNILSAITKDAFQNRRKILRHSLKNLFSEKELIKLEINSNLRAENVSVSHYCKLANYLYKKSNNLLKIN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2B_NOTSC
Sequence: NLVQFSYLIQCANHGKRPTWHYMDYGCYCGAGGSGTPVDELDRCCKIHDDCYDEAGKKGCFPKMSAYDYYCGENGPYCRNIKKKCLRFVCDCDVEAAFCFAKAPYNNANWNIDTKKRCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini.  Is directly toxic to skeletal muscle upon local application in vivo (dystrophic effect).  Also has direct nephrotoxicity in experimental mice; a single subcutaneous dose (1. 38 ug/kg) produces renal tubular and glomerular damage within 24 hours (PubMed:7580101).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 notexin, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NHAB_SHEB5
Sequence: MPATMSQAFIGNFLGNSPKWYKTAILSFLIINPLLFFYVDPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIEAVAIGMTSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFGFTKIITKVRSKVLVSLMFCLASAFLSAFLDALTVIAVIIAVAVGFYSIYHKVASGKDFGADHDHTSEGKNAAGEDQLNEEELGAFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQFGEFAVRMSPVTVPVLISGILTCYLVEKFGIFGYGAKLPTAVHRILCEYAAHEDARRTNKDNMKLIVQALVGVWLIAGLALHLASVGLIGLSVIILTTAFNGVTDEHALGKAFEEALPFTALLAVFFAVVGVIIDQHLFAPVIQWALGYEGNTQLVIFYIANGLLSMVSDNVFVGTVYINEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLSIVGVMAIQTGFLEQATQYFYDSHTIIHHSAKEVLGTVSGH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_FRACC
Sequence: MLIPRKVAHRKQHHPGRTGAAKGGTRVTFGEYGIQALESAYVTNRQIESARIAMTRHIRRGGKVWINIYPDRPLTKKPAETRMGSGKGSPEWWVANVKPGRVLFELSGVAEPVAREAMRRAIHKLPMKCRFVVREGGA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CCMA_RECAM
Sequence: MNLTKIQNLTIHNITGIRSNKIIFQNINFSLEKGSLFIIQGSNGSGKTTLLKIISGLLPKSQGDIIINNNFISENYLKDSLFYMDSTPSFKEDITLLDYLIYWNTLYNGLQNISYEYIRTSLFQLGLSHLQNKKISTLSLGQKKRLLISKLLLTNKQLWILDEPLIGLDKYWIKIFSTILLKHCKRGGIIIMSTHTDLNIKKNTFLILNTTNKFIQTLNNLI
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Peripheral membrane protein.
Protein: UBIE_SHEAM
Sequence: MSDGTSNSTHFGFKTVEADKKADLVAGVFHSVAAKYDIMNDVMSFGIHRLWKRFTIETAGARPGMKVLDLAGGTGDLTAKFSRLVGDRGEVVLADINDSMLKVGRAKLRDLGVVGNVSYVQANAEALPFPDNHFDIITIAFGLRNVTDKDAALRSMQRVLKPGGKLLVLEFSKPQHEVMRKLYDLYSFKILPKMGEFIAQDAGSYEYLAESIRMHPDQDTLKGMMQDAGLEQVDYINMTDGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: TM263_DANRE
Sequence: MSETNQQRDDLPAYLNDEPPADANKDHPQPQPGMFSRVAGGLFSVTKGAVGATVGGVAWVGGKSFDLTKTAVTSVASVPAMGVGLVKGGVSAVAGGVTAVGSAVVSKVPIGGGKKKDKSD
What is the function of this protein?
May play a role in bone development.
What are the official names of this protein?
Transmembrane protein 263.
What is the protein family that this protein belongs to?
Belongs to the TMEM263 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FBX11_HUMAN
Sequence: MNSVRAANRRPRRVSRPRPVQQQQQQPPQQPPPQPPQQQPPQQQPPPPPQQQQQQQPPPPPPPPPPLPQERNNVGERDDDVPADMVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQDLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRENMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIENTRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTLQHN
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DTL/CDT2, BCL6 and PRDM1/BLIMP1.  The SCF(FBXO11) complex mediates ubiquitination and degradation of BCL6, thereby playing a role in the germinal center B-cells terminal differentiation toward memory B-cells and plasma cells.  The SCF(FBXO11) complex also mediates ubiquitination and degradation of DTL, an important step for the regulation of TGF-beta signaling, cell migration and the timing of the cell-cycle progression and exit.  Binds to and neddylates phosphorylated p53/TP53, inhibiting its transcriptional activity.  SCF(FBXO11) does not seem to direct ubiquitination of p53/TP53.
What are the official names of this protein?
F-box only protein 11, Protein arginine N-methyltransferase 9, Vitiligo-associated protein 1, VIT-1.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TDH_FRAT1
Sequence: MKALAKLKKQPGIWIINDAPIPEYGYNDVLIKIKKTAICGTDLHIYNWDKWSQNTIPVPMITGHEFAGEVVAKGDGVTSVDIGDRVSGEGHLVCGQCRNCRAGKRHLCRKTIGIGVNVQGAFAEYLVMPAVNVFKIPDSISDDIASTFDPMGNAIHTALSFNLTGEDVLITGAGPIGLMAVKIARFCGARRIVITDINEYRLQMARDFGATVALNVAPFKNQDELVKQMRKVMSDIGMTEGFDVGLEMSGINSAISMMLDVMNHGGKLSLLGISAGDISVDWGAILFKGLTLKGIYGREMFETWYLMTSMLQAGMDMNPIITHRLHIDEFQKGFEIMKSGQCGKVILDWSS
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPRA_ECOLI
Sequence: MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIERRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLSRLDQMEQDGVVLEAMS
What is the function of this protein?
Negative regulator of the multidrug operon emrAB.
What are the official names of this protein?
Transcriptional repressor MprA, Protein EmrR.
Protein: AZIB_STREG
Sequence: MAENVQNPPVEPLAVIGMSCRFAPDLDTPGRLWEFLRAGGSAVGEMPDRRWDPYVTDSRTRDILRTTTRKGSFMRDIEGFDAEFFQITPREAEYIDPQQRIMLELAWEALCDAGLPPTSLAGTDASVYVAANSNDYGRRLLEDLDRTGAWAVNGTTFYGIANRISYFLDAHGPSMAVDTACAGSLTALHVAGQALHRGETSVAIVGGINIMASPALVVALDAASATSPDGRSKSFDKAADGYGRGEGGGVVVLKRLSDAVRDGDPVHGLVLASGVFQDGRSDGMMAPNGSAQQRMLEEIYRRSGIDPGTVQYVEAHGTGTQLGDAAEAQAIGNVFGPGRDGDNPLLIGTLKPNVGHVEAASGIAGVIKVLLGMRHGELPPSPHEEPDPGLGLEARGLRLVAEPTPWPRGEHGMRAGVSSYGVGGSIAHAVLQQAPPRPDRTERPAAAATGRPQVFPLSAASEQGVRGLAGSVAAWLRAHPETALDDLAHTFTARRSHLSRRAAVVAGTTEELLGGLDALAGGEKSPAVALASASGFGDGGAAGPAWVFSGHGAQWSGMGRELLTTEPVFAQVIDELAPVFSEELGWTPREAIEAGGPWTVVRTQAMTFAMQVALAEVWSDLGLRPGAIIGHSVGEIAAAAVAGSLDRAEAARFACRRARALGKIAGRGAMAMVPMAFADVEQRVAGRDAVVAAIAASPLSTVVSGDTAAVEALLADLEADGIQARRVNTDVAFHSPHVQEILDEVRQAAAALRAGTPRVTLYSTALADPRSDAPREGEYWATNLADPVRFHQAVRAALDDGTRVFLEVSSHPVVAHSITETALDAGVPDAHVAITLRREQPEQRTVLANLARLHSLGTPVTWSYDGDLVDVPAVRWQHKPYWIFPDTAPEQGAGLGHDPQTHTLIGARTTVASAPVQRVWQTELHMENRPYAQSHKVVGVETVPASVVLNSFITAATNEGERACGLRDIVFRIPLAAHPTRVVQVVLEQDKVRIASRIKRDQESGGVRDDEWLTHTTATVVHEPEVGARPMEDPDVIRARCPVSWTWAKVDGIFRTMGVDGYTFPWVVEELLRGEDEQFSTITVDHTPKLHPSSWTAVVDAALTASGVLVMDENSNVLRTCSHLESLSFVGPPPPRIHVHTVRDPRTPDTISMTVADESGAVVCEARGLRYVKVQDIGSGAVGPRDLVHELAWEPVEVPADAPVPSQALVVGGAAGGPALVEALTARGVRARAVPDATAIGDASLTCADVVVVAPEALLPGEAPEQAARRCAQLLVDAVQQVAAVPDERRRPRVWALTREVRAGATEAALAHAPLWGAGRIVAGERPDLWGGVIDVAENAVPQQVASLIGALPHTEDVLSLDSEGVTAARLRQVARPAEREPVDCRPDGTYLVTGGLGALGLEAARHLVEQGARRLVLIGRRGLPSRSRWDQVDDPAVAAQIAEVVALEAAGATVRVLSLDISDAEATARALDPGALDMPPVRGIVHCAGVVSDALVEKTGAANLDTTMGPKADGAMVLHRLFPAGTLDFFTMFSSCGQLARLTGQVSYASANSFLDALAALRRSRGETGTTSFAWAQWIGRGMGETTGRATILEAESRGLGGITVSEALRSWAYADRFALPYAAVMRVMPDHTLPVFSHLSVTDAGAQSADAGGVDWATVPAGELPELVLKVTHEQVAAELNLAVDDIAIDQPLLELGVDSVLTVALRVRLHRCFAVDLPPTILWSNPTVRALAEFLAAEVGGATADAEETDPVAGLPAPQQGSGTAEQLDAVAAAAG
What is the function of this protein?
Polyketide synthase that catalyzes the biosynthesis of the bicyclic aromatic compound 5-methyl-1-naphthoate in the biosynthesis of the antitumor antibiotic azinomycin B.
What are the official names of this protein?
5-methyl-1-naphthoate synthase, Azinomycin biosynthesis protein B.
Protein: RBS_ANTSP
Sequence: MRLTQGTFSFLPDLTDEQIKKQIAYAVSQNWAINIEFTDDPHPRNNYWELWGLPLFDINDVESVMYELESCRKQHSGLYIKINAFDNTRGVESCVLSFIINRPSYEPGFELIRSEDIGRNQKYSFRSYATAKPEGSRY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KHSE_STAS1
Sequence: MKEALHLKIPASTANLGVGFDSIGMALNKFLYLDVTVNDEDQWSFNHIGPNVDELPNDESHYIYQIAQKVAETYEVELPNLNVEMRSEIPLARGLGSSASALVGALYIANYFGDIELSKYELLQLATDFEGHPDNVAPTIYGGLVLGYYNGDTKVTDVSYIDTPKVDIIITIPSYKLKTIDARNALPDTFSHEKAVQNSAISNTMISALIQHNYELAGKMMEQDGFHEPYRQHLIPEFQTIKGIAKQHLAYATVISGAGPTVLTLIAPERSGELVRALKREFKDCRSELVTINETGVTTKVLYQR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC14A_DANRE
Sequence: MTLDNLKHSAILSTLFKMADDNDLLGASEFIKDRLYFATLRSKPKSTANTHYFSTDEEFVYENFYADFGPLNLAMLYRYCCKLNKKLKSFTLTRKRIVHYTSFDQRKRANAAVLIGAYAVIYLKKTPEEAYRALISGSNASYLPFRDASFGNCTYNLTVLDCLQGIRKALQHGFLNFETFDVNEYEHYERVENGDLNWITPGKLLAFSGPHPKSKVENGYPLHAPEAYFPYFRKHNVTTIVRLNKKIYDAKRFTDAGFDHYDLFFVDGSTPSDIITRRFLHICESTSGAVAVHCKAGLGRTGTLIGCYLMKHYRFTSAEAIAWIRICRPGSIIGPQQHYLEEKQASLWAHGDSLRSKQRQYQDRSVPQLISSMDNLSISTSIFKSHSLDRMEENDYAENDLGMTQGDKLRALKGRRQPRSATTGAIRVEDVKVHTRSPSQPLSRMKPPASSQGSISPLKSSKVPASSSSSSSSSSVSASAKRIGRSSSSSTNLKSTRLASSLGNLYEPNTESISSGKPPSPSSFTPHPVRTTYNYHYEVNNNNNQYSTTSSPSKSLGYNLNHSGPSGASANARLSAGEQGHQRNPPAGLSGLSTRHLSRSIPSLQSEYVQY
What is the function of this protein?
Dual-specificity phosphatase.  Required for centrosome separation and productive cytokinesis during cell division.  Dephosphorylates SIRT2 around early anaphase.  May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.
What are the official names of this protein?
Dual specificity protein phosphatase CDC14AB, CDC14 cell division cycle 14 homolog AB.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Cell projection, kinocilium. Note=Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the mitotic spindle pole and at the central spindle (By similarity). Present along both the transient kinocilia of developing cochlear hair cells and the persistent kinocilia of vestibular hair cells (By similarity).
Protein: YHDH_BACSU
Sequence: MSEQKPVQWASKIGFVMAAAGSAIGLGAIWKFPYVAGTNGGGAFFLIFVLFTILLGYPLLVGEFIFGRRNQTNAIDAYKKEAPRSAWFLTGWIGVAACFLVLSFYSVIGGWILLYIVKTASGSLSGLSQAQYGALFASIIQNPVQTLAAQLVFMALTVLVVARGVQKGIERVSAVMMPILFLLFILLVLRSLTLNGAMEGVKFLLVPHFGDLTPESILFALGQAFFTLTLGVSVMVTYSSYLPKTQNIPRSAASIVLMNIIVTLLAGLAIFPAVFSFGFQPNEGPTLLFTVLPAVFEQLPFGTLFFIGFLVAFLFAALTSAFSMVEIIVATIGKGDEKKRKKLSWTSGLLIFLVGIPCCLSYGVLSDVHLFGKTFFDIADFTVSNVLMPSGALLISLFIPLKISKSELLAEMRNGSNAGKAFFYTWFYLLRFIVPLAIIIVFLNLIGILSF
What is the function of this protein?
Putative sodium-dependent transporter.
What are the official names of this protein?
Uncharacterized sodium-dependent transporter YhdH.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRH_PSE14
Sequence: MAQQGSGYQARYKRILLKLSGEALMGSEEFGIDPKVLDRMALEVGQLVGIGVQVGLVIGGGNLFRGAALSAAGMDRVTGDHMGMLATVMNALAMRDALERANITAIVMSAISMLGVTDHYDRRKAMRHLSAKEVVIFAAGTGNPFFTTDSAACLRAIEIDADVVLKATKVDGVYTADPFKDPNAEKFDHLTYDEVLDRKLGVMDLTAICLCRDHKMPLRVFNMNKPGALLNIVHGGAEGTLIEEAQQ
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_WOLPM
Sequence: MFAVIETGGKQYLVKEGSIIKVEKLEAEEKKEVEINKVICISNSGLSYSSNATVKAEVLEQCRGEKIIIFKKKRRKNYRRKTGHRQYITVLRINEISLQK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ATPD_WOLPM
Sequence: MKKTQYNNLVSSYARVLFHVSGSRLGIIRKEVEFLLAFFKDQRDVFVYLSHPMISFAHKKEVMLSINEHLSENLVKFIMVIFANKRSSLLILILEKFLSLARENENEFEITIKSAETLKESDIKIITESLSFLGKIIKVSNVVDPSILGGFVVRYGFNLIDASLKSYLDRLVDLSKMEILKVRNFV
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FTSH_RHOM4
Sequence: MSQNERDSLELERKNTPPDGPRLPERRPRFSVWIYLAIFLALLVHFFLFWTGTDTSTIEYSQFLEYVEKGYVERVEIVNDTKVQGRFTEAAVREGLVSVPVRQTDLLRGAQTPELIRRFTTTKPADHDLTSFLLAYNERARAEGRPTVQFTARIEENWFGGLLTWIFPLILIVALWVFLLRRMSPSSQVLNIGKNRAILYDAMGDHRVTFKDVAGLDEAKEEVAEIVEFLKNPKKFTRLGGKLPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGAARVRDLFRQAKEKAPCIIFIDEIDAIGRSRGRGIMMGANDERENTLNQLLVEMDGFNTDKGVIIMAATNRPDVLDPALLRPGRFDRQILIDKPDRRERLEIFKVHTRDLILGDDVDLEVLAGQTPGFAGAEIANVCNEAALLAARKGKEAVEMEDFEQAIDRVIAGLEKKNKIISPEEREIVAYHEAGHAIVGWFLRYTDPVVKVSIVPRGLAALGYAQYLPEERYLYTKEALLDRMTMAIGGRVAEELVFGRISTGAQNDLERITRMAYAMVVDYGMSERVGYVSFNLSGQYGEQAFFDKPYSEETARLIDEEVRRIINEVRERARRILEEKRDKLEALARRLLEKEVLGPRDLVEILGPRPYGDYPSPNGKDVEELKDLQKGEPTSSSAVEAPAPQTERPESSSAP
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: AROB_JANSC
Sequence: MSDTVRVELGARAYDVEIGAGLIASAGARIAPLLSRPKVWIVTEETVAALHMDALRAGLDAANIASEALVLPPGEATKSWPHLQRIADWLLSERVERADIVIAFGGGVIGDLAGFAAAIHRRGIRFVQIPTSLLAQVDSSVGGKTGINAPQGKNLIGAFHQPSLVLADIDVLGTLMPRDFLAGYGEVAKYGMLGDAPFFEWLEANGPAMAKGDPALRQEAVRRSVQMKADIVARDETEQGDRALLNLGHTFCHALEAATGYSDRLLHGEGVAIGCALAFELSARLGLCSQEDPSRVRAHLAAMGTRRDLSDIPGDLPDADALITLMGQDKKVVAGQLRFILARGIGHAFVTADVPTDAVKALLTDALAGR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.