PharMolix/UniProtQA huggingface dataset:
Protein: DNAG_SULIK
Sequence: MKYDIKLRFEVEGIVEKTDVIGAIFGQTENLFGDEFDLRELQDKGRLGRIIVEIRTKGGKSEGEIIIPSNLDRIETALIAAMVESVDKVGPYNSKFELIEIEDIRAEKLKKIIERAKGILSSWSKEKSLDIKEVINEISSAVKVGEITEYGPERLPAGPDVDKDPNLIIVEGRADVINLLRYGYKNVIAVEGATSRIPETVVSLSKMKKTVIAFLDGDHGGDLILKELLSNNVKIDFVARAPVGREVEELTGKEIAKALSNMMPLTQYLKKIQEAEQAIAKNVIAKEEKPIQLEATQQLVQITLPQNVLEEIKKLPGTLEGVLYDNNWNLIEKVQVRDIIPKLEAYEDNKVAYIVFDGVITQRLLDLASQKNIKMIIGARIGGINKRPQNVDILTFTDIISS
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: PGRP2_HOLDI
Sequence: MKAFLVALVVAIELTLVFAGCPTIVSKNRWGGQQASQVQYTVKPLKYVIIHHTSTPTCTNEDDCSRRLVNIQDYHMNRLDFDDIGYNFMIGGDGQIYEGAGWHKEGAHARGWNSKSLGIGFIGDFQTNLPSSKQLDAGKKFLECAVEKGEIEDTYKLIGARTVRPTDSPGTLLFREIQTWRGFTRNP
What is the function of this protein?
Peptidoglycan-recognition protein probably involved in innate immunity by binding to peptidoglycans (PGN) of bacteria and activating the prophenoloxidase (proPO) cascade immune response.  Binds to 1,3-beta-D-glucan and PGN.
What are the official names of this protein?
Peptidoglycan-recognition protein 2, Hd-PGRP-2.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS5_STRMU
Sequence: MIIVIDYDAGNTANVLRALDKLGVKAELSADPQKIVAASGLILPGVGAFPAAMAELEKRGLVAVIKEAVAKGIPLLGICLGMQLLVEKGLEHCETAGFGFISGICQEISAKAGFPVPHMGWNDLQVKQKSALTAGLQGQAVYFVHSYFTDVPQEYIDVTVDYSIEVPAMIHKDNVYGAQFHPEKSGDVGLGILKKFVDLCD
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCHJ_SALTY
Sequence: MSQPCPCGSADEYSLCCGRIVSGERVAPDPSHLMRSRYCAFVMKDADYLIKSWHPTCNAAAFRDDIIAGFANTRWLGLTIFEHTWSEAENTGYVSFIARFSEQGKNGAIIERSRFIKENGQWYYIDGTRPQLGRNDPCPCGSGKKFKKCCGQ
What are the official names of this protein?
UPF0225 protein YchJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: YCEH_SHIB3
Sequence: MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRESRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKPRLDSLLAHLGD
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: MURB_WIGBR
Sequence: MKTKIFNTFSISVKAKKIISVYSEIELLQSWQKASAKDPVLFLGSGSNTLFLENYQGTIILNRIKGFHVKENNFFWNIHVCSGELWHNIVTICVNKGISGLENLSWIPGYTGAAPIQNIGAYGVEFKQVCSYVDFIFLETGEKVRLSSQECNFGYRKSIFNSSKKFFNYAIVAIGLKLKKKWKACLNYTDLSFLEKEYVSPKKIYNKIFYIRKEKIPNPVYFGNAGSFFKNPLISSKQAKKILKNYPKAPCFKQLNGNVKFSAGWIIEACGLKGYKLGKAAVYHKQASIIINTGSATGYEIAYLAKYIFCIVKKNFSIQLEPEVKFISKIGEIKASKIIS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_STUS1
Sequence: MNTLLLHCRPGFEGEVCAEISEHAAILEVAGYAKARPDSACAEFICSEPGGAERLMRRLRFADLIFPRQWARGDYLQLPETDRISVLLAHLADYPVCSSLWLEVLDTNDGKELSNFCRKFEAPLRKALVKAGRLDEQGKGPRLLLTFKSGREVFVGIAEANNSALWPMGIPRLKFPRQAPSRSTLKLEEAWHHFIPREQWDTRLAAGMTGVDLGAAPGGWTWQMVNRHIKVSAVDNGPMNADLMDSGLVEHFRADGFTFRPKRPVDWMVCDIVEKPARNAALLETWIGEGLCREAVVNLKLPMKQRYAEVKRLLERIADGLAERGVKASIGCKQLYHDREEVTCHLRRL
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
Protein: Y4193_ARATH
Sequence: METQPDTSLMETRKSLDISEKTNSGCSVEAVYSGNFSVTVADDGETALVVSIVKGDESHMGPSDTNPLPVQAKMDGDPDSSHLKILCREENTEQVAVKSELNQSLPHDISSRLSSDSDQPFFAADIENRADPVVEKDCLSIDDKKNLSTAAISNSDVASVISLKRKHSDCSGDDGNSETKPEIYESLNELKLEEEEELTTVHHESRSPSNNTTVDIFSIVKGTGRRKNLMRSNPTDKSSEAENAAGLRVKKIKRTPEDEKESMVLVEKLRKEIREAVRNKSMEDIRENQFDPKLLAAFRAAVAGPKTGEAPRRSSALAVKAKKLMLQKGKVRENLTKKIYADLNGKRKSAWHRDCEVEFWKHRCIQGRKPEKIETLKSVLSLLKNKPADTKTNFSSETPQASNPILSRLYLADTSVFPRNDNLKPLLAPKEMGNSQNNGKPTEASKTLPKISAAKGSSVKAAGSKLNSGNKQSDGQPNLTSSNSKEMVENPDDLKKDKRKWALQVLARKKALAGNNSTQDKEGSPELKGNYPLLAQLPADMRPSLATSRHNKVPVAVRQTQLYRLTEHLLKKENLLTIRRSAATELAVADAINIEKAIADKSSSKVVYLNLCSQEILHHSESKTMDNAVEPNSSSPMADSESERISSKDSDNPAVLEALRAAGLADSPPNSPTRSVEVLPEKGDSSLDKTRETGPYNVFDMDSVPDTDIFGDFEYELDEEDYFGATMAKKASVMQPDESLTKVKVVLSTVQPGKSLNPSEVVEDEETTTENLNETTNGKEDGKSFVPMELVPEAEGEGEGEGEGEGEGEGGGEILSVAECEELYGPGTEKLVERPLIEGFAENGVKAKAPDSECESNTQREFIASNFEITCIQEKKLPRSIQKCKPSEKPSKEEKGKADGFGNSITKKVEAYIKEHIRPLCKSGVINVEQYRWAVTKTTEKVMKYHSKAKSANFLIKEGDKIKKLAEQYVETASSGAHHKDKCK
What are the official names of this protein?
Uncharacterized protein At4g10930.
Protein: RL16_CUPMC
Sequence: MLQPKRRKYRKEQKGRNTGKATRGNAVSFGEFGLKAMGRGRLTARQIESARRAMTRHIKRGGRIWIRIFPDKPISKKPAEVRMGNGKGNPEYYVAEIQPGKMLYEMDGVSEELAREAFRLAAAKLPIATNFVVRQVGT
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DER_PARD8
Sequence: MGNIVAIVGRPNVGKSTLFNRLTGTRQAIVNEEAGTTRDRQYGKVEWTGKEFSLIDTGGWVVNSEDVFEEEINKQVKVAIEEADVILFVVDVLNGITDLDMEVAQILRRCKRPVIVVANKADNYDLHPASAEFYSFGLGEPFCISAINGSYTGDLLDKIVATLPEEKVEILEEELPRIAIIGRPNAGKSSLINAFIGEDRHIVTDIAGTTRDSIYTKYNKFGLNFYLVDTAGIRKKGKVNEDLEYYSVIRSIRTIENSDVCVLMLDATRGIESQDMNIFSLVQKNKKGLVVCVNKWDLIEDKSQKVIDSYTTAIRERLAPFTDFPILFISALTKQRILKVLETAKEVYENRSKRVPTAKLNEVMLPIIENYPPPAWKGKYIKIKYITQLPAGSVPSFVFFCNLPQWIKDPYKRFLENKIRENWDFTGTPINIFIREK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: FABF_STAAU
Sequence: VITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELKNFNIEDHIDKKEARRMDRFTQYAIVAAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGATVTACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSALSIKDSKIAPTIHAVTPDPECDLDIVPNEAQDLDITYAMSNSLGFGGHNAVLVFK
What is the function of this protein?
Involved in the type II fatty acid elongation cycle.  Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor.  Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] synthase 2, 3-oxoacyl-[acyl-carrier-protein] synthase II, Beta-ketoacyl-ACP synthase II, KAS II.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
Protein: EFTU_ACIAC
Sequence: MAKGKFERTKPHVNVGTIGHVDHGKTTLTAAIATVLSAKFGGEAKKYDEIDAAPEEKARGITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLDKYDFPGDDTPIVRGSAKLALEGDKGPLGEQAIDKLAEALDTYIPTPERAVDGAFLMPVEDVFSISGRGTVVTGRVERGIIKVGEEIEIVGIRDTQKTTCTGVEMFRKLLDQGQAGDNVGLLLRGTKREDVERGQVLCKPGSIKPHTHFTAEVYVLSKDEGGRHTPFFNNYRPQFYFRTTDVTGAIELPADKEMVMPGDNVSITVKLINPIAMEEGLRFAIREGGRTVGAGVVAKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_STRMK
Sequence: MSFSPQEALHRTIEHGEIFFDEMVDLMRQIMRGDVSPMMTAAILTGLRVKKETVDEIAAAATVMREFARPVPVADTSNLVDIVGTGGDGSHTFNISTCAMFVAAAAGARVAKHGNRSVSSKSGSADALEALGAVIELQPDQVAAAIDRTGIGFMFAPIHHPSMKVVAPVRREMGVRTIFNILGPLTNPASAPSVLMGVFHPDLVGIQARVLRELGTERAMVVWGRDNMDEISLGAGTLVGELRDGKVREYEIHPEDFGIAMSASRNLRVDGPEQSIQMLRAVLDNEPGPALDIVALNAGAALYVAGVASDIGDGLARARAAIANGSARQRLQQYVETTRALVA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RF2_STAEQ
Sequence: MELSEIKRNLEEYQNHLNQIRGSLDLENKETNIQEYEEMMTDPDFWNDQTKAQDIIDKNNALKSIVNGYYQLTNAVDDMSATRELLQEEYDEDMKIELEEEVQQFEEQIDQYELQLLLDGPHDANNAILELHPGAGGTESQDWVSMLLRMYQRYCEQNGFKVETVDYLPGDEAGVKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPTGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQEQEMAEIRGEQKDIGWGSQIRSYVFHPYSMIKDHRTNEETGKVDAVMDGEIGPFIEAYLRKEMDSRDV
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_STRP7
Sequence: MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSFPGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYNGWIEIELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNSFSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPDLPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVALGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVFVHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFTGFLMKATKGQANPQVALKLLAQELAKLKEN
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PROF7_PHLPR
Sequence: MSWQTYVDEHLMCEIEGHHLASAAILGHDGTVWAQSADFPQFKPEEITGIMKDFDEPGHLAPTGMFVATAKYMVIQGEPGAVIRGKKGAGGITIKKTGQALVVGIYDEPMTPGQCNMVVERLGDYLLKQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-7, Pollen allergen Phl p 12, pollen profilin variant 4.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TRPA_STAAE
Sequence: MTKLFIPYIMGNKDLIENATLLSENGADIIEIGVPFSDPVADGPVIMEAGQQAIKQGITIDYIFNQLEKHGDQIKCNYVLMTYYNIICHYGEQAFFEKCRDTGVYGLIIPDLPYELSQRLKQQFSHYGVKIISLVAMTTDDKRIKDIVSHAEGFIYTVTMNATTGQNGAFHPELKRKIESIKAIANVPVVAGFGIRTPQHVADIKEVADGIVIGSEIVKRFKSNTREEIIKYLQSIQQTLNN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CSRA_BLOPB
Sequence: MLILTRRVGETLVIGDEVTVTVLGIKGNQVRIGVNAPKEISIHREEIYQRIKSEKSQQNLC
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPA_BOVIN
Sequence: MMSAMKTEFLCVLLLCGAVFTSPSQETYRRLRRGARSYKVTCRDGKTQMTYRQHDSWLRPLLRGNQVEHCWCDGGRAQCHSVPVRSCSEPWCFNGGTCRQALYSSDFVCQCPEGFMGKLCEIDATATCYKDQGVAYRGTWSTAESGAECANWNSSGLAMKPYSGRRPNAIRLGLGNHNYCRNPDQDSKPWCYVFKAGKYISEFCSTPACAKVAEEDGDCYTGNGLAYRGTRSHTKSGASCLPWNSVFLTSKIYTAWKSNAPALGLGKHNHCRNPDGDAQPWCHVWKDRQLTWEYCDVPQCVTCGLRQYKRPQFRIKGGLFADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERYPPHHLKVFLGRTYRLVPGEEEQTFEVEKYIIHKEFDDDTYDNDIALLHLKSDSLTCARESASVRTICLPDASLQLPDWTECELSGYGKHESSSPFFSERLKEAHVRLYPSSRCTSQHLFNRTVTNNMLCAGDTRSGGDHTNLHDACQGDSGGPLVCMKDNHMTLVGIISWGLGCGRKDVPGVYTKVTNYLDWIRDNTRP
What is the function of this protein?
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen.  By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events.  During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy.
What are the official names of this protein?
Tissue-type plasminogen activator, t-PA, t-plasminogen activator, tPA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: CARP9_CANAL
Sequence: MRLNSVALLSLVATALAAKAPFKIDFEVRRGESKDDLSPEDDSNPRFVKRDGSLDMTLTNKQTFYMATLKIGSNEDENRVLVDTGSSDLWVMSHDLKCVSAPNSKRNERSFGHGTGVKLNERELMQKRKNLYQPSRTIETDEEKEASEKIHNKLFGFGSIYSTVYITEGPGAYSTFSPFVGTEGGSGGSGGSNTCTSYGSFNTENSDTFKKNNTNDFEIQYADDTSAIGIWGYDDVTISNVTVKDLSFAIANETSSDVGVLGIGLPGLEVTTQYGYTYQNLPLKLKADGIIAKSLYSLYLNTADAKAGSILFGAIDHAKYQGDLVTVKMMRTYSQISYPVRIQVPVSKIDVESSSGSTTNILSSTTGVVLDTGSTLSYVFSDTLQSLGKALNGQYSNSVGAYVVNCNLADSSRTVDIEFGGNKTIKVPISDLVLQASKSTCILGVMQQSSSSSYMLFGDNILRSAYIVYDLDDYEVSLAQVSYTNKESIEVIGASGITNSSGSGTTSSSGTSTSTSTRHSAGSIISKPVYGLLLSLLISCYVLV
What is the function of this protein?
Secreted aspartic peptidases (SAPs) are a group of ten acidic hydrolases considered as key virulence factors.  These enzymes supply the fungus with nutrient amino acids as well as are able to degrade the selected host's proteins involved in the immune defense.  Involved in triggering host polymorphonuclear neutrophils chemotaxis toward germ tubes.  Moreover, acts toward human hemoglobin though limited proteolysis to generate a variety of antimicrobial hemocidins, enabling to compete with the other microorganisms of the same physiological niche using the microbicidal peptides generated from the host protein.  Required for cell surface integrity and cell separation during budding.
What are the official names of this protein?
Candidapepsin-9, ACP 9, Aspartate protease 9, Secreted aspartic protease 9.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted, cell wall.
Protein: RFC5_MOUSE
Sequence: MTAAAPSQQRPAAARARNLPWVEKYRPQTLADLISHQDILSTIQKFISEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIVRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVQEENVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKTDIANILDWMLNQDFTTAYKNIMELKTLKGLALHDILTEVHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTSEKIQLSSLIAAFQVTRDLIVAEA
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.
What are the official names of this protein?
Replication factor C subunit 5, Activator 1 36 kDa subunit, A1 36 kDa subunit, Activator 1 subunit 5, Replication factor C 36 kDa subunit, RF-C 36 kDa subunit, RFC36.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS18_SINFN
Sequence: MAEVSSAPVRRPFHRRRKTCPFSGANAPRIDYKDVRLLQRYISERGKIVPSRITAVSQKKQRELAQAIKRARFLGLLPYVVS
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RPO5_PYRAE
Sequence: MSRISLGVKEVTVIPREEAKELLKRMKLRPWQLPWIRASDPLAQKAGAKPGDVLKIVRESPTAGEAVVYRLVVPG
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_BARHE
Sequence: MKFTLSWLKDHLETDASLDEICDKLTAIGLEVDHVDDRSYLKGFVIAKVLTAIKHPDADKLQILSVDTGADKPVQVICGAPNARAGLVGVLALPGTYVPGLDVTLSVGKIRGIESFGMMCSWAELELSNEHDGIIELPEDVPIGASFAVYAGLDDPVIDIGLTPNRSDCTGVRGIARDLAATGIGRLKELSLPQLGTTFETSLDVSLDFSQSALLCLGFAWCEVRNVQNNASPQWMQQRLNAIGLRPINALVDITNYISFDLGRPLHVFDADKIKGNLRVRCGREGEQLQALNGKVYNLGVKDCVIADEEGVVSIAGIMGGERTSCDETTRRVIIESALWDAQSIAQTGRALGLISDARYRFERGVDPAFMETGLEIATELVLRLCGGEGSKMKIVGYQQPEIRQITFPLSEIKRLTYLEIEHEQTMTILTQLGFDSEGQGNVVVVKVPTWRPDIVGKADLVEEVMRIYGLDKIKPIPLESFMEVKDPVLTVSQLRSRITRFALAGRGMRETVTWSFISEKQALAFGGGQAQLKLVNPISADMSVMRPSLLPGLLVAAQRNADRGFPDFALFEVSNIYEDDTPDKQHRVAGGIRRGTEQFGGAGRFWNGNARAVDVFDAKADALAVLEACGLESGKVQIEVGAPDWYHPGRSGVIKLGSKIILGFFGVFHPATLEKLDISGPLCGFEIFLDRIPEPKKKATKSRSPLKLSSLQMVRRDFAFVVDKMVDSSLIVRAASGADKKLIHSVQVFDVFEDLSLGEEKKSVAIEVALQPIERTLTDEDIEELALKLVENVTRMTGASLRC
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QVR_DROSI
Sequence: MWTQRNAVGNWLLVLTAVIGFLTFIWIPQTSAECQTRSIYCYECDSWTDARCKDPFHYTALPRDQPPLMTCNGCCVKMVRHQRSRYEVVRRMCTSQLQINLFMVDHVCMMESSGNGHMCFCEEDMCNSSKNLHTNGCQLHLIPIAVAVSWLMGQLLSR
What is the function of this protein?
Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation.  Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability (By similarity).
What are the official names of this protein?
Protein quiver, Protein sleepless.
What is the protein family that this protein belongs to?
Belongs to the quiver family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: NUCS_SULTO
Sequence: MTQVLLNPSLEEAYHFLVKNMYNNLITLFGDCEIQYEGRAYSHASLASRLIIIKVDGSVIVHEHTKREPINWQPPGSVIVVRKESGVLSIESIRKRPKERLYIILRRLYYLTSAEVNSGNFDIKGTEKDIVDLVLENPNLIEEGFKPIQREYRIPYGIVDLFGYDKFGTPFVLEFKRSKATLQAVSQLHRYYMFFLESYGKARGALVSPGISEKALNLIEKLRLEYIDANRIFDSITNSSRYTINISNIQRS
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGGU_ECOBW
Sequence: MNAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVDGQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN
What are the official names of this protein?
UPF0235 protein YggU.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RL17_ECO57
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PSBL_CUSEU
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: FB339_ARATH
Sequence: MASGNLPWELEEEILCRLPLGSLVRLRSVCKHWNDFFNDKWFIKKSLGCARPQFIILPESKIYSIGTIGLDGVDPKIEVRELACQFHFEAEKWAFTAACDGLLFRDFWNQGVTIWNPWLRQVGWIEYKENRDFRFCGVGYDAGKPEKGYKIFGYFNRFYDTKLKIDHRFAIFECASQAVKFIDSPEWPMLAGRGEYVSLNGNLYWTAYNEETREHFLGSFNFSTEISMRFCLLPCAKHVSGLRDKLVLTVFKGDRFALLKQSRISKDTKVLTAQYGPKARTKKNENAEKACLKSYGSLKPDRLEKLKKSMKRY
What are the official names of this protein?
Probable F-box protein At3g44130.