PharMolix/UniProtQA huggingface dataset:
Protein: FTSH_MARN8
Sequence: MTPSNEPGKQDQIPQPGPTIPNQYSFLWLSAAIFLMFLWLQGNNQQQQQELAYSEFKQAVISGQVAEVTLRTEEISGSFTDSGASRFANDSRPPSSSFITLRPQVEDPELLPLLERQEVLVRGSRSGRPWWQELILGFLPWILLLALMFWFWGAAQKRMTQGGGPFDYGKSRARRARRETSTTTLDDVAGIESAKRDISEIIDFLKSPDKYRRLGAVMPKGVLLVGPPGTGKTLLARAIAGEAEVPFFSISASEFIEMFVGVGAARVRDMFQTARKEAPALIFIDELDAVGRSRGAGLGGGHDEREQTLNQILTEMDGFEAHENVLVLAATNRPDVLDTALLRPGRFDRKITLDRPHREAREAILKVHVRKVPLAADVDLTQVAARTTGFSGADLKNLVNEAALTAARDNLVEVNNHCFEVAHDRLILGEERDAQLTPEEREAVAYHECGHAIMAYYMPKADPLTKITIIPHGMAMGVTEQTPKEDKYNYTESYLEDRIKVMLGGRSAEKIIYGEVSTGAQNDLKEATKLLRRMVGQWGMSEKIGPLGLGIGEEHVFLGREMGAPREYSEKLAEMIDSEIQSQLLAFEAFTVSFLTEHRQELDALARAVMKRETLSAGEITEVLEEARSRETA
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: NTPE_ENTHA
Sequence: MPIDKIITQINETAQLERASFEEMKRKEIDQKFEVKKWQIEADFQKEKASKLEEIERSYRQLRNKQKMQVKQEILNAKQEVLQRLFTEATLQLENEPKEEQLALMKQMIQTLPINGTARLIPGEKSADILTPAVIAEWNEELPFELIREDFTEKAQAGLIIDDAGIQYNFLFSHLIKEIQETMSAEIAKELFD
What is the function of this protein?
Involved in ATP-driven sodium extrusion.
What are the official names of this protein?
V-type sodium ATPase subunit E, Na(+)-translocating ATPase subunit E, V-type sodium pump subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: HIS6_METS4
Sequence: MLKTRVIPCLDVKDGRVVKGVQFLALRDAGDPVEAAKAYDAAGADELCFLDITASHEARGILLDVVQRTAEACFMPLTVGGGVRSVEDIRALLLAGADKVSINTAAVNNPDFVAEAAEKFGNQCIVVAIDAKRVSGPGEAPRWEIFTHGGRRATGLDAITFARTVTARGAGELLVTSMDRDGMRSGYDLGLTRAIADAVSVPVIASGGVGGLDDLVAGVAEGHASAVLAASIFHFGEATVAQAKAHMAAAGLAMRLDP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLD_MORMO
Sequence: MIMKALVLEKAGKIAIQDWQSNEVLGDDDVEIKIHTVGICGSDVHYYQHGRIGPFVVDEPMVLGHEASGVITAAGKNVKHLKVGDRVCMEPGIPDLQSPQSRAGIYNLDPAVRFWATPPIDGCLRESVIHPAAFTFKLPDNVSFAQGAMVEPLAIGMQSATKAGIKPGDIGLVIGAGTIGIITQSALAGGCSDVIICDVFDEKLKVAEKYQGLHAVNSKDQQALADKVRELTGGEGVNVLFECSGAKPVIASISDHIAPGGTAVLVGMPIDPAPLDIVAAQAKEVTFKTILRYANMYPRTIRLLSSGKLNVAPLLSATYKFKDSVEAYERAAEPVRLM
What are the official names of this protein?
D-xylulose reductase, Xylitol dehydrogenase, XDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: END4_STAAN
Sequence: MLLGSHVSMSGKKMLEGSAIEAYEYGETTFMIYTGAPQNTRRKSIEDLNITKGHEVMEKYGLSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIGAKDIVLHPGAHVGAGVDAGINKIIEGLNEVLTNDNNVRIALETMAGKGTEIGRSFEELARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQQFDPELKNKVMQQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: EFG_NITWN
Sequence: MPRQHAIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHEGAATMDWMTQEQERGITITSAATTAFWDGKRLNIIDTPGHVDFTIEVERSLRVLDGAVCVLDSNQGVEPQTETVWRQGDKYKVPRIVFCNKMDKTGADFYKCLADIVDRLGARPVALQLPIGSESNFKGMVDLVRMKALVWNNEALGAMYDIVDIPADLADKAKEYREKLVEAAVELDDDAMAAYLDGAEPDEATLKKLIRKAVLTGAFYPVLCGTAFKNKGVQPLLDAVVAYLPSPLDVPAIKGVDDKGNEVVRHADDKEPMSLLAFKIMDDPFVGTITFCRIYSGILQSGTGVVNSTREKKERIGRMLLMHANNREDIKEAYAGDIVALAGLKEARTGDTLCDPAHQVILEKMEFPDPVIEIAIEPKSKADQEKLGIALAKLAAEDPSFRVSTDQESGQTILKGMGELHLDIKVDILKRTYKVDANIGAPQVAFRERVTKRVEHSYTHKKQTGGTGQFAAVTLIVEPSEPGKGYEFESKIVGGAVPKEYIPGVEKGIESVLSSGVVAGFPVVDVKVQLIDGKFHDVDSSALAFEIATRACFREALQKGKSVLLEPIMKVEVVTPEDYTGSVIGDLNSRRGQIQGQDMRGNANVINAMVPLMNMFGYVNNLRSMSQGRATFTMQFDHYAEAPANVSAEVQKKFA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOE_STAAT
Sequence: MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALGDYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILDADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDELDEDEEVFEDEEDFND
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: MTBB1_METBF
Sequence: MATEYALRMGDGKRIYLTKEKIIAEIEDGTANAADLGEIPALNANEMEKLAEILMMPGKTVSVEQGMEVPVTHDIGTIRLDGDQGNSGVGIPSSRLVGCMTHERAFGADTMELGHIDYSFKPVKPVVSNECQAMEVCQQNMIIPLFYGAMPNMGLYYTPDGPFENPGDLMKAFKIPEAWESMEHAAEHLTRDTVWVMQKLFASGADGVNFDTTGAAGDGDMYGTLHAIEALRKEFPDMYIEAGMAGECVLGMHGNLQYDGVTLAGLWPHQQAPLVAKAGANVFGPVCNTNTSKTSAWNLARAVTFMKAAVEASPIPCHVDMGMGVGGIPMLETPPIDAVTRASKAMVEIAGVDGIOIGVGDPMGMPIAHIMASGMTGMRAAGDLVARMEFSKNMRIGEAKEYVAKKLGVDQMDLVDEHVMRELREELDIGIITSVPGAAKGIAAKMNIEKLLDIKINSCNLFRKQIA
What is the function of this protein?
Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of MtbC.
What are the official names of this protein?
Dimethylamine methyltransferase MtbB1, DMA methyltransferase 1, DMAMT 1, Dimethylamine--corrinoid protein methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the dimethylamine methyltransferase family.
Protein: ASSY_PSEMY
Sequence: MADVKKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKAQALGVKEIYIDDLREEFVRDFVYPMFRANTIYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHAIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWRWTKSPEAAPDTPTYIELTYQAGDIVAIDGKAMTPAQVLAELNRIGGENGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITLDREVAHLKDELMPKYASLIYNGFWWSPERLMLQQMIDASQANVNGVVRLKLYKGNVIVTGRKSDDSLFDANIATFEEDGGAYNQQDAAGFIKLNALRMRIAAGKGRKLI
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_CELJU
Sequence: MHCESPIVRRKSRQIMVGNVPVGGGAPISVQSMTNTETTDVAATVEQIRRIQTAGADIVRVSVPTMEAAEAFGLIRKQVNIPLVADIHFDYRIALRVADLGVDCLRINPGNIGREKRIKAVVDKARDLNIPIRIGVNAGSLEKDLQKKYGEPTPDALVESALRHVEILDGLNFYNFKVSVKASDIFMAVAAYRKLAALIEQPLHLGITEAGGLRAGTVKSAIGLGALLMDGIGDTIRVSLAADPVEEIKVGWDMLRSLKIRSKGVNFIACPSCSRQNFDVIKTMNDLELRVEDITVPLDVAVIGCVVNGPGEAKEADLGLAGGTPSNLIYIDGEPSQKLTNENLVDNLERLIRAKAAQKQAQLEADAKNIIARA
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PROA_NATPD
Sequence: MTETTEAKVDAAQTAALELANESDEARQENLQAIADAIDERRAEVLEANEKDVEAAEEMLEAGEYSQALVDRLKLSDAKLDSIIEMVRSVAGQEDPLGKTLTARELDDGLDLYKVSVPIGVIGTVFESRPDALVQIAALSLRSGNAVILKGGSEASHSNRVLYEIIREATADLPDGWAQLIEAREDVDRLLGMDDSVDLLMPRGSSAFVSYIQDNTSIPVLGHTEGVCHVYVDDAADLDMATDIAYDAKVQYPAVCNAVETLLVHEDVAEEYLPDIAARYAEADVEMRGDEATRSVLDRDIEAATDDDWTSEYGDLIVAIKVVDSLESAIDHINTNGSKHTESIVTEDDGRASTFMRRLDSASVFHNASTRFSDGYRFGLGAEVGISTGKIHARGPVGLKGLTTYKYHLEGDGHLVATYAGEDAKPFSHEEFDGEWSP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_CHLCV
Sequence: MVISPSKKQAARRHTHSVKIGNLYVGSEHSIKMQSMTTTPTADVEATVTQICALVEAKCEIARVTVQGIKEAQACEHIKERLLSMGIAIPLVADIHFFPQAAMHVADFVDKVRINPGNFVDKRNMFTGKTYTDKNYADSLLRLEEKFTPLVEKCKRLGKAMRIGVNHGSLSERVMQRYGDTIEGMVVSALEYIEVCEKLGYRDVVFSMKSSNPKVMVAAYRQLAKDLDARGWHYPLHLGVTEAGIGLDGIIKSAVGIGTLLTEGLGDTIRCSLTGCPTTEIPVCESLLKHTTTYLDLPKKENPFALENSETFVNASKKITKATPWGSVYGVFIKLMKEHLLNNTVEKLLEQLGINPTNGKKDFTAPDGIIVPKSFIGTSVIEKLKEHLLVFHHHEVPCLYNHNEEIWNSEQVLSAPFVHCHATPPFIHSTREFFEKKQSNEQPVKLVFSKDLDDEFEAAVSIATEFGALLLDGLGEAVILDLPNVSLPTVREIAFSTLQSAGVRLVKTEYISCPGCGRTLFDLPEVTTRIREKTKHLVGLKIAVMGCIVNGPGEMADSDFGFVGSKTGMIDLYVKHTCVKAHIPMEDAEEELVRLLQEHGVWKDPE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GAL3B_HUMAN
Sequence: MAAVRALVASRLAAASAFTSLSPGGRTPSQRAALHLSVPRPAARVALVLSGCGVYDGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHVIDHTKGQPSEGESRNVLTESARIARGKITDLANLSAANHDAAIFPGGFGAAKNLSTFAVDGKDCKVNKEVERVLKEFHQAGKPIGLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPYAGTAEAIKALGAKHCVKEVVEAHVDQKNKVVTTPAFMCETALHYIHDGIGAMVRKVLELTGK
What are the official names of this protein?
Putative glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial, Keio novel protein-I, KNP-I, Protein GT335, Protein HES1.
What is the protein family that this protein belongs to?
Belongs to the GATD3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RIC8B_HUMAN
Sequence: MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIPTTCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVDSWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPKEELLKPMGLKPDGTITPLEEALNQYSVIEETSSDTD
What is the function of this protein?
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.  Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction.
What are the official names of this protein?
Synembryn-B, Brain synembryn, hSyn, Protein Ric-8B.
What is the protein family that this protein belongs to?
Belongs to the synembryn family.
Protein: ATP25_YEAS1
Sequence: MNKFCLLPFHGKRIGVANIPFTILFKKGPCFLHSHITAVYYSTKGKNDSHEQSRVSKKSTFTPLETPWYLRIVDNEKELMEGKKNNHHTMNKELEIPKTSPNSLRKIADLLTGKLGLDDFLVFDLRKKSPNSVSAVNKLGDFMVICTARSTKHCHKSFLELNKFLKHEFCSSAYVEGNFNERQESRRKRRLARKSNLSKLLGRSSECSAKDLNSEAWYMIDCRVDGIFVNILTQRRRNELNLEELYAPENEKSKFQNIDSGNVPTISGVNEISSNNNILLGLRRLAQQRRRYSTINPNGLSNLRYFLQKEDFKGANKIIQSSSGTETHNIRTLEHVKNTLKDLVGQERKVDVVQWKSLFDEHSTFLTINQSAAYWPLRLEYAILLNKADPQFYSDRVFLKDYLLLKKSLGQELIREDLIALLEMVLKTQHSSHSYFNLVKQNRVIIRALNLFKGLQTEDDGSVVYDEEVISLLLNSMVADERVKLRSLYETIDHIFQTFGDKLTSGMIVSILQNLAKIKDWNKLLQVWEAITPTEGEGQDKRPWNEFINVINQSGDSHVISKIVNNGHLLWIRRLNVNVTPELCNSIKALLKTAGMENSTLEEFLVRGTNNQ
What is the function of this protein?
mRNA stabilization factor specific for the 0. 95 kb OLI1 mRNA.  Also involved in OLI1 ring formation (By similarity).
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial, OLI1 mRNA stabilization factor.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SKAP1_TAKRU
Sequence: MEAVDLLANVSVTGLLLFWGDCEFFVSEILYDENLSENAQETRKVLLNNFRVVHVRNPQEFPFPSDYKEEDGSDDNRSSSLGRSAQSDDASLASDNQDDGIPEYFGDIPPVAAQDIVNVLKQGYLEKKRKDHSFFGSEWQKRWCVLNNLVFYYFGSDKDKQQKGSFYISDYSVQLVTNLRKDSRKTSCFEFFAPGRRPFQFTAGSPQEAKEWVDQIKIVLRDLSSTVIPVDDEEEEEEEEETYDDIEGEGGPPLPQPLSGTWGRGGDTGAADEEDEDIYEVLPEESPDSADGSMERNNKPEYANYYQGLWDCSADEPDELPFQRGDLIYIISKEYNIYGWWVGELNGAVGIVPKDFLHPAYIL
What is the function of this protein?
Positively regulates T-cell receptor signaling.  Required for optimal conjugation between T-cells and antigen-presenting cells (By similarity).
What are the official names of this protein?
Src kinase-associated phosphoprotein 1, Src family-associated phosphoprotein 1.
What is the protein family that this protein belongs to?
Belongs to the SKAP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Upon T-cell stimulation, translocates to lipid rafts at the cell membrane.
Protein: PAFA_MYCA9
Sequence: MQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDSLVQLVTHDRAGERVLEDLLVDAEQRLSDEGIGGDIYLFKNNTDSAGNSYGCHENYLIVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATYCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMAETTTMLKVGTAALVLEMIESGVAFRDFSLDNPIRAIREVSHDLTGRRPVRLAGGRQASALDIQREYHARAVEHLNTREPNEQVEQVVELWGRTLDAVESQDFSKVDTEIDWVIKRKLFQRYQDRYNMELSDPKIAQLDLAYHDIKRGRGVFDLLQRKGLAARVTTDEEIKAAVDQPPQTTRAKLRGDFITAAQEAGRDFTVDWVHLKLNDQAQRTVLCKDPFRSVDERVERLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: YTHDF_DROME
Sequence: MSGVDQMKIPGNTAKSVEERNIPWSQQVDEASYENLSSPTHDEVSGNDNSMQFQYPPFNFKENCNTPWNNMNKGRKANANHDSYRRHGHSIPNNTRRDEHQVNPWNSRKPAAQSFRNENDQPSTKLDNRTSDEAQNQEVVAAPKKTTWASIASQPAKLTSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWDLPNNKPPPVPSPPSPIDLGYSDLSSDFSISSNTAPPLGARAEKVHKDTENFLKYEHKGLGNNNNFSRAKVSPTGPVRRNLGPQQPVHHAAPRPATNAGPFGPPNARRHDGGPHPSRNSERSGNYSSFRGSEFESASKFEYRDENQSRPVEATSATEELPVDSQLVLDELKDKNNYNPKVLDLKKAGSARFFVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGNIMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVWSQDKWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIEVLQILHSYNHSTSIFDDFFHYEKKQEEEVSSKRPPMHGPDGNNHAPAPLARSFNRQADDKDRDRDGRGGMSQKHFNSGGGAGFRNPGHRGGAGSGGSHNNYSEYRRGFDIHKSSSDYQFKDRDGPDFDRENDFGSHYGSNNRKNEYKHNNTNKARLKTRDRDFSTEQIKIGVRFKDTDKDKMRSNEYS
What is the function of this protein?
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs (PubMed:28675155, PubMed:33428246).  M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA processing and stability (PubMed:28675155, PubMed:33428246).  Together with Fmr1, regulates axonal growth in the mushroom bodies and neuromuscular junctions by repressing the translation of several mRNAs, such as those of chic and futsch (PubMed:33428246).
What are the official names of this protein?
YTH domain-containing family protein.
What is the protein family that this protein belongs to?
Belongs to the YTHDF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1071_MYCSJ
Sequence: MARAEGDSWDVASSVGATAAMVAAGRAVATRDPRGLIDDPYAAPLVRAVGIEFFTKVADGEFDMTELDPSSAAEMQARIDEMALRTRFFDDYFLASTAGGIRQVVILASGLDSRAYRLPWPDGTVVYEIDQPAVIDFKTSTLAGIGAEPTAERRTVAIDLREDWPAALRAAGFDSAAPTAWCAEGLLIYLPPEAQDLLFDNVTALSATGSTVATEYVPGILNFDAEKARAASAQMRERGLDLDMPSLVYHGERKHVMEYLTSLGWTMAGLPRTDLFAKHGVPMVAHDNDPLGEIVYVSGTYQNR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mjls_1071.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: CDH_CROS8
Sequence: MKRALLITVALIAVLALTTLVAWRYLFPHDPDALRHIVMQQCLPGERERQEPAPCAQVNLPAGYVVLKDINGPLQYLLMPTWKINGVESPLLLSDNTPNFFWQAWQARRWMSEKRGSPVPDSAVSLTINSRMGRSQNHFHIHISCLRPDVRAQLDAAMNAIGSRWQPFPGSLRGHDYLARRVSGEELSRRSPFMMLAEEVPQAREHMGRYSLALAPLKDGAFVLLATQRQLLQFNLAHSEELQDHDCALLHEGTP
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: 5HT1E_PIG
Sequence: HQPANYLICSLAVTDLLVAVLVMPLSIMYIVMDSWRLGYFICEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAGLMILTVWTISIFISMPPLFWRSHRQLSPPPSQCAIQHDHVIYTIYSTLGAFYIPLTLILILY
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various alkaloids and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling inhibits adenylate cyclase activity (By similarity).
What are the official names of this protein?
5-hydroxytryptamine receptor 1E, 5-HT-1E, 5-HT1E, Serotonin receptor 1E.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IPI1_NEUCR
Sequence: MGSSNKKKKEKKKDFNKAKLKVGKAKAKAANFTDTSFKSKSIVVNQHTLAALDGVDLVGLFKQHLNQAINSKSDKLRQEALVQLTKDLSSKPIFNPVGVPNLLTKLLPLITDSVANVRTNFLKLLRALPPSDVAPHVEKILMYIRGGMTHLSTEIRSDTLSVLDWLIDVCPDETVSCPGGWLKTMNSFSSMLGWNPSVASTLSVKGWTSATKTSLNKVSKKNGEAQAKQITTLAKFLEAGFRPETPLPYDEQRYWDSIYRMPTTPNPFAYLNLWGAQRDEDGEMYPDRISRQQVFERKWRAAIKTGVMGAKQEGGVIGRAASVLDKVLRTAEEGGKKVVEEQKIEEVEEAEA
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein ipi1.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCIU_ECODH
Sequence: MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEERGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKLCHIIWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: RLMG_YERPY
Sequence: MSQLDLGTQSLELERFPPQENSNTLQAWEAADEYLLQNIDLSQIDGRPVLVFNDQFGTLACALHAYRPFSSSDSYMSQLATAHNLRLNHLDESAVTLLSSVDDLPEAPKLVVIKIPKALALLEHQLRALRRVVAPDTVIIAGAKSRDVHNSTLQLFEKILGPTKTTLAWKKARLIHCEVADIPLADAPETIDWPLPNTDYIIHNHANVFSRNNLDIGARFFMEILPYDVTGKIADLGCGNGVVGLIALEQNPLAEMLFVDESYMAVASSELNITVNRPQDLSRCEFMVSHGLAGVERESLQLVLCNPPFHQQHAVSDHVAWQMFCDAKRCLKAGGELMIVGNRHLDYFHKLKRLFGNCETLDSNQKFMVLKSVKQASSRSEGGGSGSLDMSYSDF
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_MYCTU
Sequence: MRTPCSQHRRDRPSAIGSQLPDADTLDTRQPPLQEIPISSFADKTFTAPAQIRNFCIIAHIDHGKSTLADRMLQLTGVVDERSMRAQYLDRMDIERERGITIKAQNVRLPWRVDKTDYVLHLIDTPGHVDFTYEVSRALEACEGAVLLVDAAQGIEAQTLANLYLALDRDLHIIPVLNKIDLPAADPDRYAAEMAHIIGCEPAEVLRVSGKTGEGVSDLLDEVVRQVPPPQGDAEAPTRAMIFDSVYDIYRGVVTYVRVVDGKISPRERIMMMSTGATHELLEVGIVSPEPKPCEGLGVGEVGYLITGVKDVRQSKVGDTVTSLSRARGAAAEALTGYREPKPMVYSGLYPVDGSDYPNLRDALDKLQLNDAALTYEPETSVALGFGFRCGFLGLLHMEITRERLEREFGLDLISTSPNVVYRVHKDDGTEIRVTNPSDWPEGKIRTVYEPVVKTTIIAPSEFIGTIMELCQSRRGELGGMDYLSPERVELRYTMPLGEIIFDFFDALKSRTRGYASLDYEEAGEQEAALVKVDILLQGEAVDAFSAIVHKDTAYAYGNKMTTKLKELIPRQQFEVPVQAAIGSKIIARENIRAIRKDVLSKCYGGDITRKRKLLEKQKEGKKRMKTIGRVEVPQEAFVAALSTDAAGDKGKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDK_TRIL1
Sequence: MERTFAIIKPDAVERGLSGKIITKIEEAGFAIVGMKKIHLSRAQAEGFYYVHKERPFFNDLCSFMSRSPVIVMCLQKENAIADWRTLMGATNPANAEPGTIRKEFAKNIEENSSHGSDAPETAAFEIPYFFNSFELVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.