PharMolix/UniProtQA huggingface dataset:
Protein: ISPH_NAUPA
Sequence: MIIEKAKSYGFCFGVKRAVEIAEESQNAVTLGPLIHNPLEIERLAKNYNVKYVETIEDIDENVKRVIVRTHGIPKDKLQNLKEKNVEIIDATCPFVKKPQEIVEEMSKQGYDIVIFGDKNHPEIQGVMSYSVHNRVYVVLDPKELEGIRLKEHIATVAQTTRKINDYLKITNYLIQNYKEVRVFNTICNATFENQDAVRELAKKADIMIIIGGKNSSNTKQLYNIAKEFCEAYLVESEEELKKEWFEGKKHCGISAGASTPEWLVEKIISRIKELA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PRDM7_HUMAN
Sequence: MSPERSQEESPEGDTERTERKPMVKDAFKDISIYFTKEEWAEMGDWEKTRYRNVKMNYNALITVGLRATRPAFMCHRRQAIKLQVDDTEDSDEEWTPRQQVKPPWMAFRGEQSKHQKGMPKASFNNESSLRELSGTPNLLNTSDSEQAQKPVSPPGEASTSGQHSRLKLELRRKETEGKMYSLRERKGHAYKEISEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPNRSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLITKGRNCYEYVDGKDKSSANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVWSGDEYGQELGIRSSIEPAESLGQAVNCWSGMGMSMARNWASSGAASGRKSSWQGENQSQRSIHVPHAVWPFQVKNFSVNMWNAITPLRTSQDHLQENFSNQRIPAQGIRIRSGNILIHAAVMTKPKVKRSKKGPNS
What is the function of this protein?
Histone methyltransferase that selectively methylates 'Lys-4' of dimethylated histone H3 (H3K4me2) to produce trimethylated 'Lys-4' histone H3 (H3K4me3).  May play a role in epigenetic regulation of gene expression by defining an active chromatin state.
What are the official names of this protein?
Histone-lysine N-methyltransferase PRDM7, PR domain zinc finger protein 7, PR domain-containing protein 7, [histone H3]-lysine4 N-methyltransferase PRDM7.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: AXO_DROME
Sequence: MAFPYIWALLPLICSASGLSLPNMTSTDAVVAGGGILPILVAGNPGNLGSSNMSLSGGGGLAGSSTGGQSLPDTGGGNSAGGSPAGGSSGTGGGGSNSGISGNNSAMIQGQKSNQYEKCAGPGDPGPCKQYIYKWRYEPTTNECTNFIWGGCEGNPQNRFGTEAECLFHCIGGPHTLPPFLQSTTREPSTTESSMLLGLPYTQSPAQSPDGMGGAEGGDGTTPVPIEQRGPELTFAETGQGKTFIFAKNNTFIQMDGDIIQTFQLRLCREISFQFRTRLPHGLLVYHNVKNPDRINLDPYALYVIVEKGQLKVVHVFGKHSTSVTVGESLNRDEWHSVMVRIDVHGARLIARVDNSQEEVYLKGLNHEYNYGVSTNLPSVVLVGGLSSEEKLHGVKYITESFVGCIRNVVLSSGKAASDLLPIAPLVATKHENVNEGCSDMCESRHNLCFVGSRCINHYGGISCDCFGTHYEGEHCDIYTATIITLRGASYVSYRIYDWKDRVHSSTRRISLMFRTNFDDSALFYASGESLKHQYIAASIKNQSVHVEMDFGDNVMSTVLTDDLTRGYWHNLTILHEQRTVSIILDQQQKVLELPATASGNMLFDPEIYFGGGPELHKKKGLASHNNFVGSLKYVYYNDISILYELQRGNPKVHYHGVLEAEFVENEVNVIPITYPFATSHIWWPINHAEEFNIKFDFRSSRPGAVLAYSDVTTSAGNGFWEIRLTSDKLSFDLVPDVNNNVTHSTTIKINRATSWHSVELDYKLGEIRFTVDYRHTLSQMYGLTFNIGDKLIIGSSLKSAAMGLVGCIRDIEINGHLIEPRHVVKTERVVGEVALDNCNYIDPCKRPNTCEHGGKCFVKDDRVTCDCKHTGYIGKNCHFTKYRKTCEELALLGFTKSDVYLIDIDGNGVFPPAHVKCDFQSLENATKTIVEHNLPSQVDVRSARESDFSFNIRYREFSPHMLQELISHSLYCTQYIKYDCYRAQLELHSATWFTSSAKNLTVDFLGNVKRGACPCSVNKTCVDPNQSCNCDVKENKWNSDEGYYQDPQSLGITNMYFLQQKDMDDEAQGRITLGPLECVETNTQKYVVTFTTSQSYIEVPGWRKGDIAFSFRTTGEKAILLFQPPIRPHYPSFMVALTGDDQLTFTFTLSTGTTRELVINSHRRLNGGEWHKIWIDYNQYHVRFMINTDYQMLDLLPEEEFGPFEGSMYIGGATFDLLKKLSVKAGLIGCFRGLVVNGEILDIYSYMSVHLSEIIKDCKPSCVPSPCRNGAQCKELWSSFKCVCNNPWAHIGEFCETNINEKALTFINRESFLMRNYLSVGATPVILMHGINGERDVLKGILNQDLLINLRTYDTNALVLYANDHYNNFVHLYISLNREIVFLYNYGDEIVNLTLLDDTLMASLKSIQVAIVRGEQETRMHVNEHSVSIDRGTLLLDEYANKPWSNPEKEVLSPHRPPAPPTEYFQFHVGGYDPANLLRPNVDAPALEGYIGCVRGLKIGAQLIDLADINERNIAPTQEGVLPNCQIKCDAEPCKNGGTCQEHFAEQLSTCDCEHTSFLGEFCSEEKGADFSGESTLQRKFELPGTGRVDYVRLQLAFSSFDLRRANRIMLLMQTEAERSYYLLLAITSDGYLQLEEDRDNGQTVGARIDRNFLNSARHSVYYVRNGTQSQLFIDREQVPLSEFAARVLTTGGDAGSNRVQIGGINSTDSRFAVFKSYSGCLSNIYIQVNGHVMKPLEEYMLFTKSGADNITVINPQGVRSAQCNAKFDVSEQPTQEPMVNVSMIPEPWVEEPPARVPYIPRFVYDENKQEDSTQVVFLTLTSVFVIIVICCLLEVYRSHLAYKKRIERETDEDIIWSKEQATKMHESPGVKAGLLGGVTAGSGNGLPPYTYKALPQEDKKPGNGAPLVGILKNGSATPSQPGTPTALSKNGDIASRIEEEEEEEDEAPAQKAAEKSGENEEPPAKDTTASEIKESQAQPPEQLAKDTTDASAAPKASKETEAQAEPSEPSSQLNSAQNGQLAQMEQAARGDEVQVPSLPHPIQPPDAIFMPNLPQKAQQRQPQEHKSRHKATDDTEAPKQQQQQQQQQQSFDVATNANGSSLPASRVKNPEEPGGKSPLVPMRQHHSKVTRPPPPPTLFLENSLLQRQFANPISYLGGPRLQPRSNRTSIDSILSLD
What is the function of this protein?
May have serine protease inhibitor activity (Probable).  Might play a role in the glial-neuronal signaling pathway that is important in establishing the electrical properties of axonal membranes (PubMed:10037607).
What are the official names of this protein?
Axotactin.
What are the subcellular locations of this protein?
Cell projection, axon. Membrane; Single-pass type I membrane protein. Note=Localizes to longitudinal axon tracts as well as to an axonal scaffold in the brain (PubMed:10037607). A secreted form might exist (Probable).
Protein: CLYBL_RAT
Sequence: MALCVLQNAVRGAAALPRLKASLVASVCRPGYSSLSNHKYVPRRAVLYVPGNDEKKIRKIPSLKVDCAVLDCEDGVAENKKNEARLRIAKTLEDFDLGTTEKCVRINSVSSGLAEADLETFLQARVLPSSLMLPKVEGPEEIQWFSDKFSLHLKGRKLEQPMNLIPFVETAMGLLNFKAVCEETLKIGPQVGLFLDAVVFGGEDFRASIGATSNKDTQDILYARQKIVVTAKAFGLQAIDLVYIDFRDEDGLLRQSREAAAMGFTGKQVIHPNQIAVVQEQFTPTPEKIRWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNIVTLATSIKEK
What is the function of this protein?
Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism.  Converts citramalyl-CoA into acetyl-CoA and pyruvate in the C5-dicarboxylate catabolism pathway.  The C5-dicarboxylate catabolism pathway is required to detoxify itaconate, a vitamin B12-poisoning metabolite.  Also acts as a malate synthase in vitro, converting glyoxylate and acetyl-CoA to malate.  Also displays malyl-CoA thioesterase activity.  Also acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate.  Also has very weak citramalate synthase activity in vitro.
What are the official names of this protein?
Citramalyl-CoA lyase, mitochondrial, (3S)-malyl-CoA thioesterase, Beta-methylmalate synthase, Citrate lyase subunit beta-like protein, mitochondrial, Citrate lyase beta-like, Malate synthase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit-like subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y3982_ORYSJ
Sequence: MAGGNTHRKKSCACCKEYLEHLGGKMRCFLRRMAADSMHSMIMPDRFVSHFGGKIPGTIKLESPNGILYVVEVTECMNKTLLQCGWEAFVDAHNIKEGESLLFRHIENSRYEVLILDSDDCEKVFSCAGIRNGSCVQDKTVDPVDSSGSSSNDTTQSSRSRNTENLTAMCSSSEKSGEDSPSGYEFHESVEPQTPSGSDYVLSRRTYLSEAQKERVVTHIQDIQPEITVFVAVMKKCNLQSPAPYLVISSRYASVHFPRETATITLQRPSKRKKWYPRFYKRIDKSDHMLRGQWQNFVHDNCLQEEDICLFVPTKGGRNFAFTVHLLQAEVTHSRDGTDVHKIGSSQNKRNSKMASQVHIKEAPGGDVSSESNKHGVSHESLESEDSDGPSEPPYISSMRRRLSQLQKKTVEEKVRAIQSEIPICVATISKLAGSGGKGKFRGLELSSRYAASYLPDKNHQTLVLQCKGMIWQINLVVRRRYTKGKRWFLTAGWRKFAHDNRLRVGDFCLFELKKKKKLTMEVHIISNLQRYPEVE
What are the official names of this protein?
B3 domain-containing protein Os03g0619800.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRE_NOCSJ
Sequence: MTLDATLAADIDAVCRLTGQFTLRSGQQATEYFDKYLFEADPQLLLRVAREMVGLLPDGTDLLGGLELGGVPIATMVSSLTGRPALYVRKKAKEYGTCKLAEGPDVAGRRVTLIEDVITTGGAVRDATRALRAAGAEVDVVVCAIDRSPAGEHPLADVGLEVRPVLTKAELDAAREAGA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: FOLD_CLOPS
Sequence: MDKILSGKTVAIDIKGQIKSYTEELKASGKSLKISSILVGDDGGSVYYQNFQEKLANNLGIDFEKIKLDESISEENLKLKIEELNKDDSVNGIMLLLPLPKHIDERVVTNLIDADKDLDCLSEVSVGRFYKGEKCFMPCTPNSVITLLKAYNIEIEGKEVVIIGRSNIVGKPLFQMFLNENATVTVCHSKTKNLKEVCKRADILVVAIGRANFIDSSYVREGAVVIDVGTSEVNGKITGDVNFDDVYEKASLITPVPGGVGSLTTTLLLKNVCKELD
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: VIAA_YERPP
Sequence: MLSLATLDMLLSISEGELIEEMVVGLLAAPQLAIFFEKFPRIKRALMKDIPGWKQNLQQRIREASVPPGLANEFSLYQQSLLEDSPQFYAHLPDIVAQLQDLHSPFATQAKTLVQTADLAKNPPGGDSLQTLFLQRWRVSLILQTITIHHQLLEQEREQLLAELQRRLALSGALEPILTTNDNAAGRLWDMSQGHLQRGDYQLLLQYGDFLQQQPELIRLAEQLGRSRSAKAQPAPDARYEPYTVMVRQPDSVPEEVSGIHQSNDILRLLPTELVMLGMSELEFEFYRRLLERRLLTYRLQGDNWQEKTQQRPVSLKQNDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALLRIALADNRRCYIMLFATEIIHYELSADNGIEQAIRFLNQHFRGGTDLAACLANTLNKMEDREWYDADAVIISDFIAQRLPEELVRKIKIQQQAHQHRFHAVAMSAYGKPGIMRIFDHIWRFDTSLKSRLIRRWKR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: ACCA_BACCR
Sequence: MAELEFEKPVVELRNKIRELKDYTKNSQMDFSEEIRILEEKLENLEEDIYGNLKVWDRVQIARHAERPTTLDYIEHLFTDFFECHGDRLFGDDAAIVGGIAKYKGMPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRLMKQAEKFNRPIICFIDTKGAYPGKAAEERGQSEAIARNLFEMAGLTVPVICIVIGEGGSGGALGLGVGDYIHMLENSTYSVITPEGAAAILWKDAGKAKEAAEAMKITAADLKELGVIDEIIPEARGGAHRNILKQSENIDLMIQKTFQQLNGISKDELIEKRYEKYMKIGQVSFSNASIWIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UIDR_ECO57
Sequence: MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLLDLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS
What is the function of this protein?
Repressor for the uidRABC (gusRABC) operon.
What are the official names of this protein?
HTH-type transcriptional regulator UidR, Uid operon repressor.
Protein: SYP_MYCVP
Sequence: MITRMSELFLRTLRDDPADAEVPSHKLLIRAGYVRPVGPGLYSWLPLGLKVLRKIENIVRNEMNAIGGQEILFPALLPRAPYETTNRWTEYGDTLFRLQDRRNNDYLLGPTHEEMFTLTVKGEYSSYKDFPLRLYQIQNKYRDEARPRAGILRGREFLMKDSYSFDIDDDGLKNAYIAHREAYQRIFDLLKVRYVIVSAVSGAMGGSASEEFLAESDVGEDTYVRCLQSGYAANVEAVVTMVPEPISSEQIAGLASATVHHTGDTPTIATLVDWANGADLGRTVTAADTLKNVMLKVREPGGEWELLGVGVPGDREVDDKRLGAALEPAEYAMLDDADFARYPFLVKGYIGPKALLANGVRYLVDPRVVDGTAWITGADELGKHVVDLVAGRDFTPDGTIEAAEVREGDPSPDGAGPLVAARGIEIGHVFQLGRKYADAFGADVLGENGKPVRLTMGSYGIGVSRLVAVIAEQHHDELGLRWPSTVSPFDVHVVIANKDADARTGATELAAELDRLGVDVLLDDRTASPGVKFKDAELLGVPWIVVVGRGWADGIVELRDRFGGDKHEIPVDGAAERISAALAGA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERG27_KLULA
Sequence: MSSSKVAVVTGTNSNLGLNIVYRLIERSEPEDNLTIVVTSRTLPRVRECIDLIKAFVNTINRTGSVDYDYLLVDFTNMISILDAHYSLSKRYDHINYFFVNAAQGVYSGIDWLGAVKEVFSSPLEAVTNPTYKIQRVGVKSKDGMGLVFQANVFGPYYLIQKLLPLLQAGQGTVVWVSSIMSAPKYLSLQDIQLLESDVSYEGSKRLVDLLHSATYKEMKKLGIRQYLTHPGIFTSLSFFQYLNVFTYYGMLFLFYLARWIGSPWHNIQGYKAANAPVYVATMANPHFEKEQMKYGSATFRDGLEYIKTDEVDTTGCEDVYKYISNLKLQWDEKLKDQIKPTRIPL
What is the function of this protein?
Responsible for the reduction of the keto group on the C-3 of sterols.
What are the official names of this protein?
3-keto-steroid reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
Protein: PAND_BURMA
Sequence: MQRHMLKSKIHRAAVTHCELHYEGSCAIDEDLLEAANIVENERIDIWNVNNGERFSTYAIKGERGSGMISLNGSAARRAQLGDLVIIAAFAMIDEQELKAGWKPDLVFVDEDNKIKGSRDHVPTQNWT
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTRB_MORLA
Sequence: MKLPIAKRIPHPHELHGDVREDDYYWLKDRDNTEVIQYLEEENRYYHEIMRPLQEQTEQIYESMVDRVPDSEMKVPVQHGQFFYYSRLDKNKQYPIYARKQAASRALLQDATEEVVLDLNELAEEDDYLSVTVQRMTTDHSRLAYLENRDGTDRYTIYIKDLNTGELLSDRVPNVYIYGSMEWCRCGDYIFYTTVDEHQRPCQLWRHRLGSDVESDELIFEEKDDTFTLFISKSQSGKFIFVYSSSKTTSEIHMIDTDSPLSPLQLVDERRDGILYDVEHWEDDLLILTNEGALNFQLLRCPLNDLSSKVNVVEYNEERYLQEMYPFRDKLLIAGRENGLTQIWVVHDGELQQISWDEPLYTVAVLSEQSYDTNEVLIQYESLLTPKTTFGLNLQTGEKQCLQVAPVSGEYDRSQFRQEQLWATGRSGVKVPMTAVYLEGALDNGPAPLILYGYGSYGSNSDPRFDPYRLPLLEKGIVFVTAQVRGGSEMGRGWYEDGKMQNKRNTFTDFIAAAKHLIDQNYTSPTKMAARGGSAGGLLVGAVANMAGELFKVIVPAVPFVDVVTTMLDTSIPLTTLEWDEWGDPRKQEDYFYMKSYSPYDNVEAKDYPHMYITTGINDPRVGYFEPAKWVARLRAVKTDNNTLVMKTNMGAGHFGKSGRFNHLKEAAESYAFILDKLGVEAEEKVLNHR
What is the function of this protein?
Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues.
What are the official names of this protein?
Protease 2, Oligopeptidase B, Protease II.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9A family.
Protein: KPRS_PORGI
Sequence: MNNENNFSVFSGTNSRYLAEKICNSLGCPLGRMNIEHFADGEFAVSYEESIRGRDVFLVQSTFPSSDNLMELLLMIDAAKRASAHYITAVIPYFGWARQDRKDKPRVSIGAKLIADLLSKAGITRLITMDLHADQIQGFFDVPVDHLYGSTVFMEYIRKNMPLENLVVATPDVGGTKRANSYAKHLGVPMVICHKSRLKANEIAEMRIIGDVQDKDVLLVDDIVDTAGTITKAADLMKENGARSVCAIASHAVMSDPASMRVDQSTLKEMIFTDSIPYPHKCEKVKILSVADLFAEAIKRVCSHESITTLYYF
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_SHELP
Sequence: MIVGLGTDIVEIARIADKVPAAGDEAALAKCPLAKRVLTQAEMAIFVASSQPGRYLAKRFAAKEAAAKALGTGIGRGVSFQHIEISNDANGAPLIAFQGGAAERLSLLGGSRAHLSIADEKHYATATVILESN
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_THEMA
Sequence: MKGFIAYIPAGFPDLETTRKILIALNELGITGVEIGVPFSDPVADGPVIQLAHSVALRNGVTIKKILEMLSEISVDYDLYLMSYLNPIVNYPEGKEKLLDELKKLGVKGLIIPDLPLREVKNVDIAYPIVPFVAPNTKDEEIDLINSVQAPFVYYISRYGVTGEREDLPFADHIKRVKERIKLPLFVGFGISRHEQVKKVWEIADGVIVGSALVRIMEENPKDEIPRKVVEKVKELLGK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CLCA_ECOBW
Sequence: MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASASENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CDT3_ORYSJ
Sequence: MYNPPAAQEMSYSDHVKKRHEDKGCLYACLFTLCCCFCCYETCECCLECLCCC
What is the function of this protein?
Confers resistance to heavy metal ions (e. g.  aluminium) by chelating them at the plasma membrane of root cells, thus stopping their entry and reducing their accumulation (PubMed:23888867).  Binds to and confers tolerance to aluminium (Al) (PubMed:23888867).
What are the official names of this protein?
Protein CADMIUM TOLERANCE 3, Cd tolerant 3, OsCDT3.
What is the protein family that this protein belongs to?
Belongs to the CYSTM1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PLAS_CHLRE
Sequence: MKATLRAPASRASAVRPVASLKAAAQRVASVAGVSVASLALTLAAHADATVKLGADSGALEFVPKTLTIKSGETVNFVNNAGFPHNIVFDEDAIPSGVNADAISRDDYLNAPGETYSVKLTAAGEYGYYCEPHQGAGMVGKIIVQ
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin, chloroplastic, PC6-2.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Loosely bound to the inner thylakoid membrane surface in chloroplasts (PubMed:8399201).
Protein: NDHH_NOSP7
Sequence: MTRLETRTEPMVLNMGPHHPSMHGVLRLIMTLDGEDVVDCEPVIGYLHRGMEKIAENRTNVMYVPYVSRWDYAAGMFNEAVTVNAPEKLAGVAVPKRASYIRVIMLELNRIANHLLWFGPFLADVGAQTPFFYQFREREMIYDLWEAATGYRMVNNNYFRVGGVAADLPYGWVDKCLEFCDYLLPKVDEYERLVTDNPIFRRRVEGIGTITREEAINWGLSGPMLRASGVQWDLRKVDHYECYDDFDWDVQWETAGDCFARYVVRMREMRESVKIIRQAIKGLPGGPYENLEAKRLAAGKKSEWDAFDYQFIGKKVSPTFKIPKGEIYARVESGKGELGIYLVGDDNVFPARWKIRAADFNNLQIVPHLLRGMKVADIVVILGSVDVIMGSVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase subunit H, NDH-1 subunit H, NDH-H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RUVC_TREDE
Sequence: MGILKAASSKKNLRPCVIGIDPGLANTGYGIISFSNNRFECIEYGSISTEPHLLQGERLLKIFDKVSELIEKYRPKEAGIETLYFAKNATSAMSVSEARGVVLLALAQGGVRVGEYAPNSIKKAVTGIAQAEKRQVQEAVKLILGLKEIPRPDHAADALAAAITKINLGDVGEVRAYV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TM104_PONAB
Sequence: MAGEITETGELYSSYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLVLLVFLGFMSFVTTTFVIEAMAAANAQLRWKRMENLKEEEDDDSSTASDSDVLIRDNYERAEKRPILSVQRRGSPNPFEITDRVEMGQMASMFFNKVGVNLFYFCIIVYLYGDLAIYAAAVPFSLMQVTCSATGNDSCGVEADTKYNDTDRCWGPLRRVDAYRIYLAIFTLLLGPFTFFDVQKTKYLQILTSLMRWIAFAVMIVLALVRIGHRQGEGHPPLADFSGVRNLFGVCVYSFMCQHSLPSLITPVSSKRHLTRLVFLDYVLILAFYGLLSFTAIFCFRGDSLMDMYTLNFARCDIVGLAAVRFFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPWVVDRVVFPTITLVPPVLVAFCTHDLESLVGITGAYAGTGIQYVIPAFLVYHCRRDTQLAFGCGVGNKHRSPFRHTFWVGFVLLWAFSCFIFVTANIVLSETKL
What are the official names of this protein?
Transmembrane protein 104.
What is the protein family that this protein belongs to?
Belongs to the TMEM104 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSA7L_MACFA
Sequence: MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICALDDHVCMAFAGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGIPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDNEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEEAEKKKSKKSV
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).  Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions.  The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions.  Plays a role in hepatitis C virus internal ribosome entry site-mediated translation.  Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation.  Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
What are the official names of this protein?
Proteasome subunit alpha type-7-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.