PharMolix/UniProtQA huggingface dataset:
Protein: 17KD_RICAM
Sequence: MKLLSKIMIIALAASTLQACNGPGGMNKQGTGTLLGGAGGALLGSQFGKGKGQLVGVGVGALLGAVLGGQVGAGMDEQDRRIAELTSQKALETAPNGSNVEWRNPDNGNYGYVTPNKTYRNSTGQYCREYTQTVVIGGKQQKAYGNACRQPDGQ
What are the official names of this protein?
17 kDa surface antigen.
What is the protein family that this protein belongs to?
Belongs to the rickettsiale 17 kDa surface antigen family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RL4_PSEF5
Sequence: MQLNVNDAQAIEVSELTFGGEFNETLVHQAVVAYMAGGRQGSKQQKTRSDVSGGGKRPWRQKGTGRARAGTIRSPIWRGGGTTFAARPQDHSQKLNKKMYRAAMRSILAELVRTDRLVVVQDFAVETPKTKDLLGKLNNMSLTDVLIVSDAVDQNLYLAARNLPHVDVRDVQGSDPVSLIAYDKVLITVSAVKKFEELLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: U71A2_PANGI
Sequence: MKSELIFLPAPAIGHLVGMVEMAKLFISRHENLSVTVLIAKFYMDTGVDNYNKSLLTNPTPRLTIVNLPETDPQNYMLKPRHAIFPSVIETQKTHVRDIISGMTQSESTRVVGLLADLLFINIMDIANEFNVPTYVYSPAGAGHLGLAFHLQTLNDKKQDVTEFRNSDTELLVPSFANPVPAEVLPSMYVDKEGGYDYLFSLFRRCRESKAIIINTFEELEPYAINSLRMDSMIPPIYPVGPILNLNGDGQNSDEAAVILGWLDDQPPSSVVFLCFGSYGSFQENQVKEIAMGLERSGHRFLWSLRPSIPKGETKLQLKYSNLKEILPVGFLDRTSCVGKVIGWAPQVAVLAHKAVGGFVSHCGWNSILESVWYDMSVATWPMYGEQQLNAFEMVKELGLAVEIEVDYRNEYNKTGFIVRADEIETKIKKLMMDEKNSEIRKKVKEMKEKSRVAMSENGSSYTSLAKLFEKIM
What is the function of this protein?
Component of the triterpene saponins (e. g.  PPD-type ginsenosides or panaxosides) biosynthetic pathways (PubMed:25320211).  Glycosyltransferase that catalyzes the biosynthesis of compound K from protopanaxadiol (PPD) (PubMed:25320211).
What are the official names of this protein?
UDP-glycosyltransferase 71A27, PgUGT71A27.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: CAIE_SHIF8
Sequence: MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFSGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
What is the function of this protein?
Overproduction of CaiE stimulates the activity of CaiB and CaiD.
What are the official names of this protein?
Carnitine operon protein CaiE.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: METK1_ATRNU
Sequence: MAAAVDTFLFTSESVNEGHPDKLCDQISDAVLDACLAQDPESKVACETCTKTNLVMVFGEITTKANVDYEKIVRQTCRDIGFVSADVGLDADNCKVLVYIEQQSPDIAQGVHGHLSRRPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYYNENGAMVPIRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIARQAAKSIVAAGLARRCIVQISYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKETFDFRPGMIAINLDLLKGGSRYLKTAAYGHFGRDDADFTWETVKPLKWEKPQA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate (By similarity).  May be involved in the synthesis of betain in response to abiotic stress such as high salinity (PubMed:15695433).
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHI_ERWT9
Sequence: MKQPARTSQVKKPAARVKRKTREEINQEARDRKREKKHSGHASGSRANPATVSQKGDKSQSVKDPRIGSKKAIALGTDAPVRQPANPVKAAKPAVEKKPRLTPEEELAKLENDERLDALLDRLENGEALSAEDQAWLDQSLDRIDVLMEQLGIALDDDAEDEKAEEDMYRLLKGSHRTPE
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: SSRP_ALIB4
Sequence: MANKKDTKKNLVFKNKKAFHDFTILETLEAGIVLEGSEVKAIREGRVNLKDSFVRIIKGEVFLLNAHISHLSTTHSTYRPDERRSRKLLLHSKQIDKMYSKVTKDGITLVALKLYFNDKNMIKIEVATAQGKKLHDKREDLKAKTMKRETEQVLKSFK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RIMP_ACICJ
Sequence: MQINLQTDGGGPNRPPFLLPGYPESFPVNDTRPQHTGLEGRIAELIAPGLESIGYELVRVAIMGKQTPTVQIMADRADQTPLSLDDCERISHLVSAVLDVDDPISSAWTLEVSSAGIDRPLTRVKDWNRYAGHLARIDLDVPTASGRKRLTGTVLGADEAQARVKLDSGETVDLPHAHIRRAKLVLTEELIKATETPPAAN
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_HAEIN
Sequence: MSKKSGLSFLWLSAVAFVIDLLTKYIVVQKFDLYESVNVLPVFNLTYVRNYGAAFSFLADHSGWQQYFFILLALAISGMLVYFLAKNNAEQKIQNSAYALIIGGALANMVDRAYNGFVVDFFDFYWDIYHYPVFNIADIAICIGAGLLVLDAFKSEKKKVQDKQVEKCGQK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: XT3_XENTR
Sequence: GLASTLGSFLGKFAKGGAQAFLQPK
What is the function of this protein?
Has antibacterial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E. coli, when in combination with XT1 and XT6.
What are the official names of this protein?
Antimicrobial peptide 3, Levitide-like peptide, XT-3.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIE_ECO27
Sequence: MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: KGUA_RICCN
Sequence: MTTKNKRVLQKCAYREEFKGDMERSTAATSKLPLEVELSRNSKGLIIILSSPSGTGKSSLAKALLKIDNNLRLSISATTRKPRLGEVEGINYYFKTGLEFEELVKQNKFLEYAKIYDNYYGTPKEYVEMLLNQGLDVLFDIDWQGARSIKKNATNVVTIFVLPPNIEVLEQRLRNRATDNEEAIKLRMQLAQNEISHANEYDYVVTNDDFDRTLKKIHAIIVAARDKAF
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_CAMJJ
Sequence: MQVITSVKEAKQIVKDWKSHQLSIGYVPTMGFLHDGHLSLVKNAKTQDKVIVSIFVNPMQFGPNEDFSSYPRDLERDIKMCQDNGVDMVFIPDAAQMYLKNFSTYVDMNTITDKLCGAKRLGHFRGVCTVLAKFFNILNPDIVYMGQKDAQQCVVVRHMVDDLNFDLKIQICPIIREEDGLAKSSRNVYLSEEERKASLAISQSIFLAEKLVQEGEKDTSKIIQAMKDILEKEKLIKIDYIELVDFNTMENIKNIADNVLGAVAAFVGKTRLIDNFLVQGLK
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_HISS2
Sequence: MEKLNFLLKNTALLPTNLQKERLVQLVLLLNKWNKAYNLTSVRDPMEMLVKHILDSIVVSPYLQGNIFIDVGTGPGLPGLPLAIINPDKKFFLLDSLGKRISFIRNAVRELELTNVEPVLSRVEEFKPDHQFDGVLSRAFASLKDMTEWCQHLLTDQGFFYALKGQYNMEEVSALSAQFSVDKIIELNVPELVGKRHLVLLKKIRINLMNYL
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_METTH
Sequence: MRILLIHSDYLKYETKNKTGIAEEIPEDKMQGDFRESLVVFTAVEAEDEDNPESVIENAVNEIIKVFNDVKAENVVIYPYAHLSSSLSSPKTAVEVLEGMESALRSEGVDVSRVPFGWYKAFKISCKGHPLSELSRSIRPQPPKVEEESEESEWFILHRGETVKPGDFEFKNRDLENLVKYELGELESSGEEPPHVRLMREKGLADYEPSADVGHLRWYPRGRLIRDLLADYVYMLVTSEGAMPVETPIMYDLEDEAIRVHAEKFGERQYRMKNRKELMLRYACCFGAFRILSDSFLTWKNLPASIYELSTYSFRLEKKGEVVGLKRLRGFTMPDLHTVCADLDQSLEEFARQVEMCMRTGQDLQVNYEVIFRATADFYEEYREWVHEVADKIGKPVLLEILPSRKHYWIAKMDFAAIDYLGRPIENPTVQIDVESGERFGITYVNSDEEEVNPIILHCSPTGSIERVICSLLEKTAIEMDEKPPMLPLWLSPTQVRVLPIAERHMEYASDLVSELIAADVRADLDDRSETLGKKIRNAAQDWVPYVVVIGDSEMEGKLTVNVRETGEKLQMGLDELIERIRAETEGMPFRRLPLPVKLSERINF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDCB_ECOL6
Sequence: MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
What is the function of this protein?
Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction.  The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate).  Both intermediates are unstable and short-lived.  The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia.  In the low water environment of the cell, the second step is accelerated by RidA.  TdcB also dehydrates serine to yield pyruvate via analogous enamine/imine intermediates (By similarity).
What are the official names of this protein?
L-threonine dehydratase catabolic TdcB, L-serine dehydratase, Threonine deaminase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: Y1384_PHOLL
Sequence: MEIRVFRQDDFEEVITLWERCDLLNPGVDPEVDIERKLTHDPDLFLVAEVVGEVVGTIMGGYDGHRGSAYYLGVHPEFRGRGIANALIARLEKKLIARGCPKIVLIVPEDNDATIYMCEKLEYEDRHQESVIFSKRLIVDQEY
What are the official names of this protein?
Acetyltransferase plu1384.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. YpeA subfamily.
Protein: BGAL_ERWT9
Sequence: MAKTDPLTLQQLLAQRHWENPALTQLNRLPAHTPLASWRNADAARGDLASPSQRLLDGEWGFSYFDRPQAVPDAWINGDLPQVGRLSVPSNWQLSGYDAPIYTNVQYPIPTDPPRVPDDNPTGCYSLTFHCQPAWLQSGQTRIIFDGVNSAFYLWCNGEFIGYSQDSRLPAEFDLSQRLLEGENRIAVMVLRWCDGSYLEDQDMWRMSGIFRSVSLLHKPHVRLDDIHIDTRLSPEYRSAQLRVLALCSLTDASAYQLKVTLWRDDTLIAQHQQPFGTPVVDERGRYLDRTRLSLQIDQPLLWNAETPHLYRAVIALLDADGTLIEAEACDVGFRQVEVSGGLLKLNGKALLIRGTNRHEHHPDRGQVMDEPAMIADILLMKQHNFNAVRCSHYPNHPLWYRLCDRYGLYVVDEANIETHGMQPMNRLADDPSWFSAFSERVTRMVQRDRNHACIIIWSLGNESGHGSTHDALYGWIKSDDPSRPVQYEGGGADTAASDIICPMYARVDRDQPFEAVPKWSIKKWIALPEETRPLILCEYAHAMGNSLGGFSRYWQAFRQYPPLQGGFVWDWADQNLTRQAADGSSWQAYGGDFGDMPNDRQFCMNGLVFADRSPHPALFEAKRAQQFFQFQLENTSPITLGITSEYLFRHSDNERLCWRIEHHGEQVAGGQITLNLPPEGTVSLMLGELPSLAGELWLRVEVIQPAATAWSPANHRVAWDGWQLPAALSLPKPDVPGEQPRLHPQSQLIEVVQAGQRWQFCRQSGELIQWLQADKPQLLSPLRDLFVRAPLDNDIGISEANRIDPHAWAERWQRAGYYRLESQLLRLQTDILNDGVQIRSEQAWLADGEPRFLSRKCYRINRQGEMLLEVEVDIAAGLPEPARIGLHCQLAEVAEEVCWLGLGPHENYPDRRLAAEFSRWQLPLGALSTPYVFPCENGLRGGTRELTFGHWHIRGDFHFSLSRHSVEQLRKTSHRHLLRDEAGCWLTLDGFHMGVGGDDSWSPSVDEEFLLRARQYRYRLILTRG
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: HUTU_YERPE
Sequence: MTTQNRFRDNEIRAPQGTQLTAKSWLTEAALRMLMNNLDPDVAENPKELVVYGGIGRAARNWECYDKIVESLINLNDDETLLIQSGKPVGIFKTHSNAPRVLIANSNLVPHWANWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHFGGSLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLKTRYVDEQATDLDDALARIEKYTATGVAVSIALCGNAAEILPELVRRGVRPDMVTDQTSAHDPLNGYLPKGWNWEEYRQRAQHEPALVINAAKISMAEHVEAMLAFHNMGIPTFDYGNNIRQMAHDMGVIRAFDFPGFVPAYIRPLFCRGIGPFRWVALSGNPDDIYKTDAKVKALIPDDAHLHHWLDMARERIRFQGLPARICWVGLGQRAKLGLAFNEMVRSGELSAPVVIGRDHLDSGSVASPNRETEAMQDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVVVCDGSDEAAERIARVLHNDPATGVMRHADAGYDIAVNCAQEQGLNLPMVAATQGKKS
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPOO_METMA
Sequence: MTDCDLCGKGIPTVIPVRTYPPLLRFAYPEGVWKGLCETCLDSAQKTYLEVNRNHTSCRRGKCSLCGSKTGVFSVELQIPDFSKGIVRKDVDVCYRCLKLVDEAYIRYKREQIEQDHEQGRIHGHEHVHPH
What is the function of this protein?
Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2):heterodisulfide oxidoreductase system.  The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines.  Catalyzes the oxidation of methanophenazine to dihydromethanophenazine.  It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane).  It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  It also catalyzes the oxidation of F(420)H(2) with quinones such as 2,3-dimethyl-1,4-naphthoquinone, 2-methyl-1,4-naphthoquinone and tetramethyl-p-benzoquinone.
What are the official names of this protein?
F(420)H(2) dehydrogenase subunit O, F(420)H(2)-dependent phenazine dehydrogenase subunit O, F(420)H(2)-dependent phenazine oxidoreductase subunit O, FPO subunit O, Methanophenazine hydrogenase subunit O, Methanosarcina-phenazine hydrogenase subunit O.
What is the protein family that this protein belongs to?
Belongs to the FpoO family.
Protein: RL32_LYSSC
Sequence: MAVPFRRTSKTAKRKRRTHFKLSVPGMVTCPNCGEAKLSHRVCKACGQYKGKEVVSK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: UVRB_METS3
Sequence: MKKFKLNSPYKPLGDQPKAINSLVDGINKGEKEQTLLGVTGSGKTFTMANVIEKVQKPTLVISHNKTLAAQLYEEFKEFFPDNAVEYFVSYYDYYQPEAYVPRTDTFIDKESSVNEEIDIMRHSATQSLLSRDDVIVVSSVSCIYGIGSPEDYGEFAFGIAVGDNYDRSDIIRKLVFMQYERNDIEFARGHFRVRGDVIEINPVHGTPPVRVELFGDEIDAISLIDKVTGKKTESLKRYMIFPAKHFVVGQDKMDTAIRNISDELDERLNEFNLSNKLLEAQRLEQRTRFDIEMLQEMGYCPGVENYSMHLSGRKWGEKPYSLLKYFPEDYLTIIDESHVTLPQIRGMYNGDRARKETLVEHGFRLPSAKENRPLRFDEFESSINQIIYVSATPGAYELSRSSNIVEQIIRPTGLVDPEVIIRPVKGQVEDLLGEVKKRAKKDERVLVTTLTKKMAEDLTDYYAKIGVKVRYMHSEIDTLERIDIVDDLRRGTFDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRNETSLIQTIGRAARNINGQVIMYVDEMTDSVKNATAITSKRRKIQIKYNEKHGIVPKTTKRALKDKKVAEDLDIEGTDISKIPKDELRLLISDLENDMKEAAAKLDFERAASLRDQIATLKGLKKDSS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_NOCFA
Sequence: MRHLLSVTDLDRTAATELLDEAERFEQALLGREVHKLPTLRGRTVMTVFYENSTRTRVSFEVAGKWMSADVINVSASSSSVSKGESLRDTALTLHAAGADALIVRHPASGAAHQIARWMDGWARESGRSHGPAIVNAGDGMHEHPTQALLDALTLRQRLGDIEGKRVVIVGDILHSRVARSNVFLLHTLGAEVVLVAPRTLLPVGVQSWPARVSHHLDAELPGADAVLMLRVQAERMNGGFFPSAREYSVNYGLSERRLALLAEHAVVMHPGPMLRGMEIASAVADSPQAAVLQQVTNGVHLRMAVLFRLLVGAQEAIA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y2439_NITEU
Sequence: MMGWNTVERNWKELKGKLKETWGDMTDDELDVIAGKREQLVGKIQTKYEIAREEAERQVNAFAHDCDAAKEPLKNVGEAVSSRQKSVKKRSLYT
What are the official names of this protein?
UPF0337 protein NE2439.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: IDI2_CHLL2
Sequence: MSDSLSNITIERKHNHVEICLHEAVGFDRKSAGFDEIEFIHNALPEIRFSDIDLSTTFLGRKIGAPLMISSMTGGFEKASLLNRRFAEAAEHFGIPLGIGSMRQALENSTQKESFAIVRKYAPSVPVFANIGAPEVARGLSASDIGILLELIEADALIVHLNAAQELFQPEGNTDFRHVLDQLSHLCATVPVPVIVKEVGCGISGVCAQRVLDAGVKVIDVAGAGGISWQKVEEIRYVRQRERENRFSPEALDDLLNWGIPTARCIAEVSDLKKHTVHTDFEIIASGGIRSGLDIAKSLALGARIGASAGQLLNAAHEERLEETIETWLNDLRAVLFLTGTTSPDKLQKQHLILKHRPIL
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_STRP4
Sequence: MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFKGVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FLRT3_RAT
Sequence: MISPAWSLFLIGTKIGLFFQVAPLSVMAKSCPSVCRCDAGFIYCNDRSLTSIPVGIPEDATTLYLQNNQINNVGIPSDLKNLLKVQRIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPGGLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTSLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGMAIKDLSAELFDCKDSGIVSTVQITTAIPNTAYPAQGQWPAPVTKQPDIKNPKLTKDQRTTGSPSRKTILITVKSVTPDTIHISWRLALPMTALRLSWLKLGHSPAFGSITETIVTGERSEYLVTALEPESPYRVCMVPMETSNLYLFDETPVCIETQTAPLRMYNPTTTLNREQEKEPYKNPNLPLAAIIGGAVALVSIALLALVCWYVHRNGSLFSRNCAYSKGRRRKDDYAEAGTKKDNSILEIRETSFQMLPISNEPISKEEFVIHTIFPPNGMNLYKNNLSESSSNRSYRDSGIPDLDHSHS
What is the function of this protein?
Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners.  Plays a role in the spatial organization of brain neurons.  Plays a role in vascular development in the retina (By similarity).  Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (By similarity).  Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1.  Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity).  Promotes neurite outgrowth (in vitro) (By similarity).  Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length (PubMed:15485775).  Plays a role in the regulation of the density of glutamaergic synapses (PubMed:22405201).  Plays a role in fibroblast growth factor-mediated signaling cascades.  Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning.  Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development.  Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity).
What are the official names of this protein?
Leucine-rich repeat transmembrane protein FLRT3, Fibronectin-like domain-containing leucine-rich transmembrane protein 3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Synapse, synaptosome. Postsynaptic density. Cell projection, dendrite. Synapse. Presynaptic cell membrane. Cell projection, axon. Cell projection, growth cone membrane. Cytoplasmic vesicle. Endoplasmic reticulum membrane. Cell junction, focal adhesion. Secreted. Note=Detected on dendritic punctae that colocalize in part with glutamaergic synapses, but not with GABAergic synapses (PubMed:22405201). Proteolytic cleavage in the juxtamembrane region gives rise to a shedded ectodomain (By similarity).