PharMolix/UniProtQA huggingface dataset:
Protein: ACCA_BACCQ
Sequence: MAELEFEKPVVELRNKIRELKDYTKNSQMDFSEEIRILEDKLENLEEDIYGNMKVWDRVQIARHAERPTTLDYIEHLFTDFFECHGDRLFGDDAAIVGGIAKYKGMPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRLMKQAEKFNRPIICFIDTKGAYPGKAAEERGQSEAIARNLFEMAGLTVPVICIVIGEGGSGGALGLGVGDYIHMLENSTYSVITPEGAAAILWKDAGKAKEAAEAMRITAADLKELGVIDEIIPEAKGGAHRNVLKQSENIDLMLRKTFEQLNGISKDELIEKRYEKYMKIGQVSFSNASIWIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_STAA1
Sequence: MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAAF9_HUMAN
Sequence: MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITSFVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYELQDVSLNLWNVYSKMDPMSLESLLSDDLVAFEHQWTSFFANFDTEIPFLLELSESQAGEPFRSYFSHGMISSHITENSPNRQPFVLFGNHSTRENLNAGNFNFPSEGHLVRSTGPGGSFAKHMVAQCVSPKGPLACSRTYFFGATHVPYLGGDSKLPKKTEQIRLLSQIYAAVIEAVLAGIACYAKTSSLTKAKEVAEQTLGSGLDSFELIPFKAALRSKMTFHIHAVNNQGRIVPLDSEDSLSFVKTACMAVYDIPDLLGGNGCLGSVVFSESFLTSQILVKEKDGTVTTETSSVVLTAAVPRFCSWLVEDNEVKLSEKTQQAVRGDESFLGTYLTGGEGAYLYSSNLQSWPEEGNVHFFSSGLLFSHCRHRSIIISKDHMNSISFYDGDSTSTVAALLIDFKSSLLPHLPVHFHGSSNFLMIALFPKSKIYQAFYSEVFSLWKQQDNSGISLKVIQEDGLSVEQKRLHSSAQKLFSALSQPAGEKRSSLKLLSAKLPELDWFLQHFAISSISQEPVMRTHLPVLLQQAEINTTHRIESDKVIISIVTGLPGCHASELCAFLVTLHKECGRWMVYRQIMDSSECFHAAHFQRYLSSALEAQQNRSARQSAYIRKKTRLLVVLQGYTDVIDVVQALQTHPDSNVKASFTIGAITACVEPMSCYMEHRFLFPKCLDQCSQGLVSNVVFTSHTTEQRHPLLVQLQSLIRAANPAAAFILAENGIVTRNEDIELILSENSFSSPEMLRSRYLMYPGWYEGKLNAGSVYPLMVQICVWFGRPLEKTRFVAKCKAIQSSIKPSPFSGNIYHILGKVKFSDSERTMEVCYNTLANSLSIMPVLEGPTPPPDSKSVSQDSSGQQECYLVFIGCSLKEDSIKDWLRQSAKQKPQRKALKTRGMLTQQEIRSIHVKRHLEPLPAGYFYNGTQFVNFFGDKTDFHPLMDQFMNDYVEEANREIEKYNQELEQQEYHDLFELKP
What is the function of this protein?
May act as an effector for ARL3.
What are the official names of this protein?
Dynein axonemal assembly factor 9, DNAAF9.
Protein: RL34_STAAS
Sequence: MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: GLYR1_DANRE
Sequence: MATVHLRIGDLVWGKLGRYPPWPGKVVSPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHPHKEEMIKVNKGKRFQQAVDAVEEYLKKAKGKDQSHSDDKSKSDKGRKAAKPMKIIEEDDEDAFKGGSSDKPASSMEPITKRLKIIEEDTRSTSIQAADSTAINGSITPTDKRIGFLGLGLMGSGVVSNLLKMGHVVTVWNRTAEKCDLFIQEGARLGRTPAEVVSMCDITFSCVSDPKAARDLVLGPSGVLQGIRPGKCYVEMSTVDPETITELSQVITSRGGRFLEAPVSGSQQLSNDGMLVIVAAGDRSVYEDCSSCFQAMGKTSFFIAGEAGNAARMMLILNMVQGSFMATIAEGLTLAQATGQSQQTFLDILCQGQMASTFVDQKCQNILQGNFKPDYYLKHIQKDLRLAISMGDSVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH
What is the function of this protein?
Cytokine-like nuclear factor with chromatin gene reader activity involved in chromatin modification and regulation of gene expression.  Acts as a nucleosome-destabilizing factor that is recruited to genes during transcriptional activation.  Recognizes and binds histone H3 without a preference for specific epigenetic markers and also binds DNA.  Interacts with KDM1B and promotes its histone demethylase activity by facilitating the capture of H3 tails, they form a multifunctional enzyme complex that modifies transcribed chromatin and facilitates Pol II transcription through nucleosomes.
What are the official names of this protein?
Cytokine-like nuclear factor N-PAC, NPAC, Glyoxylate reductase 1 homolog, Nuclear protein NP60, Putative oxidoreductase GLYR1.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. NP60 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Found in actively RNAPolII-transcribed gene bodies.
Protein: PAFA2_HUMAN
Sequence: MGVNQSVGFPPVTGPHLVGCGDVMEGQNLQGSFFRLFYPCQKAEETMEQPLWIPRYEYCTGLAEYLQFNKRCGGLLFNLAVGSCRLPVSWNGPFKTKDSGYPLIIFSHGLGAFRTLYSAFCMELASRGFVVAVPEHRDRSAATTYFCKQAPEENQPTNESLQEEWIPFRRVEEGEKEFHVRNPQVHQRVSECLRVLKILQEVTAGQTVFNILPGGLDLMTLKGNIDMSRVAVMGHSFGGATAILALAKETQFRCAVALDAWMFPLERDFYPKARGPVFFINTEKFQTMESVNLMKKICAQHEQSRIITVLGSVHRSQTDFAFVTGNLIGKFFSTETRGSLDPYEGQEVMVRAMLAFLQKHLDLKEDYNQWNNLIEGIGPSLTPGAPHHLSSL
What is the function of this protein?
Catalyzes the hydrolyze of the acetyl group at the sn-2 position of platelet-activating factor (PAF) and its analogs, leading to their inactivation (PubMed:9494101).  Hydrolyzes propionyl and butyroyl moieties approximately half as effectively as PAF (By similarity).  Also catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively.  Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position (By similarity).
What are the official names of this protein?
Platelet-activating factor acetylhydrolase 2, cytoplasmic, PAF:lysophospholipid transacetylase, PAF:sphingosine transacetylase, Platelet-activating factor acetyltransferase PAFAH2, Serine-dependent phospholipase A2, SD-PLA2, hSD-PLA2.
What is the protein family that this protein belongs to?
Belongs to the serine esterase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor. Endoplasmic reticulum membrane; Lipid-anchor. Note=In resting cells, localizes to intracellular membranes and cytoplasm. Translocates from the cytoplasm to intracellular membranes upon oxidative stress.
Protein: CHEW_ECO57
Sequence: MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLDSAASEVA
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB (By similarity).
What are the official names of this protein?
Chemotaxis protein CheW.
Protein: CALMB_ARBPU
Sequence: EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKETDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVAMMTSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin-beta, Cam B.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: CHLB_CLACY
Sequence: KRLPGESGVSVNQVIPEGASLKYLKDLPRAWFNAVPYREVGLMTATFSEKEYGMPYISITPMGISNTADFIEQIGKLVNVWASVLSERKLNYRLYVENQTKFV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex (By similarity).
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: METAA_BRUC2
Sequence: MPIKIPDDLPATSVLEAEGVMVMREADAVRQDIRPLRIGLLNLMPNKVTTETQIARLLGATPLQVELTLVRMTNHVARHTPADHMLSFYCPWEEVNDQRFDGFVITGAPVERLPFEEVTYWDEMRRVFDWTQSHVHRTLNICWAAQAAVYHFHGMKKYDLPAKASGVFRQRSLVPASPYLRGFSDDFAIPVSRWTEVRKSDIPADSGLKVLVDSTETGLCLLDDPRHRSLHMFNHVEYDTTSLADEYFRDIQVQPEAKVPVNYFPGDDAKRPPENRWRSHAHLLFGNWINEMYQSTPYDIERIGKV
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIG2_CAEEL
Sequence: MLKFTAISFVLLNAAESVDHQKPIRALDSQPLLKFTRTPNDSNVTFGEKFVLSCGANGAPLPSIYWELNGMRIQGEETSNVYENILNDGKQVSNAAMVSSHYRIPCATARNSGAYKCIIDNGLTKLEHVAKVFVGGNKTNCALNDNGAPFISMTVDFRLEISNNAVALSCRSETATEWSWHKGEQLLTNDGERYQMFPSGDLIIRNISWSDMGEYNCTARNHFGETTAITFLYPTLAK
What is the function of this protein?
Probably not involved in maintaining the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP, RMEV, AVK and HSN neurons.
What are the official names of this protein?
Zwei Ig domain protein zig-2, 2 Ig domain protein zig-2.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_STAAC
Sequence: MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFATISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGVH
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMP_SYNSC
Sequence: MPHPLLPDLETLATKVAASKGFALCGIQLLTHMSPMTLEVQIRHSSGADVSLDDCAGFSGVLGDALEASTLLTDAYVLEISSPGIGDQLSSDRDFETFRGFPVEVHHRDKDDSEQRLEGLLLERDADTLQINIRGRIKRIARDCVIGVRLTSPGS
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_RHIME
Sequence: MPLINLPAFAGDLLADFERRNTLRVDTPVIQPAEPFLDMAGEDLRRRIFMTESETGESLCLRPEFTIPVCLRHIETATGTPQRYAYLGEVFRQRREGSSEFYQAGIEDLGDPDTAAADARVVGDAMFVLANRLPGERLKVTLGDQSVFEAVIAACGLPGGWQKRLIHAFGDQKQLERLLAALADPKSPGVFGHDVERVAALGMLEDEERLVAHIGETMKATGYSTNAGRSPRDIARRLKEKVELAAIRLDKEALGVMRAFLALDLPLADAPAALHRFAGKARLKIDDALALFDARVAALARAGADPGLMRYRAAFGRPLDYYTGLVFEIGVEGTPAVLAGGGRFDRLLTLLGAREHIPAVGFSLWLDRIEQAIAAGRAE
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1355_LISIN
Sequence: MTTIIAFIFVFGLIVFFHELGHFLFAKRAGIMVKDFSIGFGPKIFAYRKKETQYTIRLLPIGGYVRMAGEDGEEIELKPGYRVGLELTPEETVSKIIVNGKDQYVNAQPIEVSLCDLEKELFIEGYEDYDDTKKVRYQVERNALVIDGKIETMITPYDRSFNAKSLGNRAMTIFAGPLFNFILAILIFTALAFVQGGVPSTDNTLGNIMPDGAAAQAGLEKGDEVLSINGKETKSWTDIVQSVSENPGKTLDFKIDRDGKTQDIDVKPATQKENGKEVGKIGVETPMDTSFTAKITNGFTQTWNWIVQIFTILGNMFTGGFSLDMLNGPVGIYTSTQQVVQYGFMTVLNWTAVLSINLGIVNLLPLPALDGGRLMFFLYELVRGKPIDPKKEGIIHFAGFALLMVLMILVTWNDIQRAFF
What are the official names of this protein?
Putative zinc metalloprotease Lin1355.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LCF4_YEAST
Sequence: MTEQYSVAVGEAANEHETAPRRNIRVKDQPLIRPINSSASTLYEFALECFTKGGKRDGMAWRDIIDIHETKKTIVKRVDGKDKPIEKTWLYYELTPYITMTYEEMICVMHDIGRGLIKIGVKPNGENKFHIFASTSHKWMKTFLGCMSQGIPVVTAYDTLGESGLIHSMVETDSVAIFTDNQLLSKLAVPLKTAKNVKFVIHNEPIDPSDKRQNGKLYKAAKDAVDKIKEVRPDIKIYSFDEIIEIGKKAKDEVELHFPKPEDPACIMYTSGSTGTPKGVVLTHYNIVAGIGGVGHNVIGWIGPTDRIIAFLPLAHIFELTFEFEAFYWNGILGYANVKTLTPTSTRNCQGDLMEFKPTVMVGVAAVWETVRKGILAKINELPGWSQTLFWTVYALKERNIPCSGLLSGLIFKRIREATGGNLRFILNGGSAISIDAQKFLSNLLCPMLIGYGLTEGVANACVLEPEHFDYGIAGDLVGTITAKLVDVEDLGYFAKNNQGELLFKGAPICSEYYKNPEETAAAFTDDGWFRTGDIAEWTPKGQVKIIDRKKNLVKTLNGEYIALEKLESIYRSNPYVQNICVYADENKVKPVGIVVPNLGHLSKLAIELGIMVPGEDVESYIHEKKLQDAVCKDMLSTAKSQGLNGIELLCGIVFFEEEWTPENGLVTSAQKLKRRDILAAVKPDVERVYKENT
What is the function of this protein?
Activates long-chain fatty acids (LCFA) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids.  Also facilitates the transport of LCFAs into the cell, either by active transport or by decreasing the intracellular LCFA concentration (PubMed:7962057, PubMed:11477098, PubMed:12601005).  Contributes, with FAA1, to the activation of imported myristate (PubMed:7962057).  Also involved in long-chain base (LCB) uptake.  In contrast ot LCFA uptake, LCB uptake does not require ATP, suggesting that the enzyme is directly involved in LCB uptake (PubMed:27136724).  Involved in the sphingolipid-to-glycerolipid metabolic pathway, converting the shingolipid metabolite hexadecenoic acid to hexadecenoyl-CoA, which is then further converted to glycerolipids (PubMed:22633490).
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase 4, Fatty acid activator 4, Fatty acyl-CoA synthetase, FACS, Long-chain acyl-CoA synthetase 4.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Lipid droplet.
Protein: COX8A_THEGE
Sequence: MSVLTSLLLRGLTGSARRLPVPRAKVHSMPPEEELGTLEKAIALTSCFVSLFLPAGWILSHLEDYKRPE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8A, mitochondrial, Cytochrome c oxidase polypeptide VIII-liver/heart, Cytochrome c oxidase subunit 8-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: HPS_STAAW
Sequence: MELQLAIDLLNKEDAAELANKVKDYVDIVEIGTPIIYNEGLPAVKHMADNISNVKVLADMKIMDAADYEVSQAIKFGADVITILGVAEDASIKAAIEEAHKNNKQLLVDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLESLRTVKSVIKNSKVAVAGGIKPDTIKEIVAESPDLVIVGGGIANADDPVEAAKQCRAAIEGK
What is the function of this protein?
Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
What are the official names of this protein?
3-hexulose-6-phosphate synthase, HPS, D-arabino-3-hexulose-6-phosphate formaldehyde lyase.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. HPS subfamily.
Protein: KTHY_BRUSU
Sequence: MSGLFITFEGGEGAGKSTQIALLASHLRNHGFDPVITREPGGSPGAEAIRHVILSGNAETYGPAMEALLFAAARADHVDQLIRPALAEGRIVLCDRFIDSSRAYQGVTGNLDATYMAAIERIAIDGAMPDLTLVLDICAERGLSRAGKRRGSDTADRFEKEDIAVHEARRQAFLEIARQEPARCKVIDADRSQEKIADEIRSVVDTILTEKGLL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: KTI6_ARATH
Sequence: MKTFQLMMISFLFVAITTTSGVVSEGNDVVYDGEGDPVKPNVPYYISFMTSDYNMWICRMQYGSTDPNSCPQQPLMVTHPNLAAPTPVMFVLANKSDVVRESAKLKIKFVGPRQCGKSGFWKVVQRNSSEGEVFLNGSKSMSHNDSTFAIHKTNEYYKFTFGDGDYPTTISMTNDYPIYRLLSKRLSGEMEIYFYKNLTTSEG
What is the function of this protein?
Exhibits Kunitz trypsin protease inhibitor activity.
What are the official names of this protein?
Kunitz trypsin inhibitor 6, AtKTI6.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: MENG_CORGL
Sequence: MAKADLDKDPFDVASMFDDVGKNYDLTNTVLSFGQDRVWRKRTRQRLDLKPGEKVLDLAAGTAVSTVELAKSGAFCVACDFSQGMLAAGKDRDVSKVVGDGMQLPFADNSFDAVTISYGLRNIHDFRAGLKEMARVTKPGGRLTVAEFSTPVIPVFGTVYKEYLMRLLPQAARAVSSNPEAYIYLADSIRAWPSQAELAREINQNGWSDCGWQNLTFGIVALHSAIKPEN
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RS20_NEIMA
Sequence: MANSAQARKRARQSVKQRAHNASLRTAFRTAVKKVLKAVEAGDKAAAQAVYQESVKVIDRIADKGVFHKNKAARHKSRLSAKVKALA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MEL_POLHE
Sequence: MKFLVNVALVFMVVYISFIYAAPEPEPAPEAEAEADAEADPEAGIGAVLKVLATGLPALISWIKRKRQQG
What is the function of this protein?
Main toxin of bee venom with strong hemolytic activity and antimicrobial activity.  It has enhancing effects on bee venom phospholipase A2 activity.  This amphipathic toxin binds to negatively charged membrane surface and forms pore by inserting into lipid bilayers inducing the leakage of ions and molecules and the enhancement of permeability that ultimately leads to cell lysis.  It acts as a voltage-gated pore with higher selectivity for anions over cations.  The ion conductance has been shown to be voltage-dependent.  Self-association of melittin in membranes is promoted by high ionic strength, but not by the presence of negatively charged lipids.  In vivo, intradermal injection into healthy human volunteers produce sharp pain sensation and an inflammatory response.  It produces pain by activating primary nociceptor cells directly and indirectly due to its ability to activate plasma membrane phospholipase A2 and its pore-forming activity.
What are the official names of this protein?
Melittin, MEL, MLT.
What is the protein family that this protein belongs to?
Belongs to the melittin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Alpha-helical peptides form toroidal pores in the prey.
Protein: RHAM_ECO27
Sequence: MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKARNLLFATIEIESEERWNAVASTDVCQRWWKYMIDVMPANADNSPVSSELQEVFYLP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPSB_STAAW
Sequence: MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENHKLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: SPEA_THEVB
Sequence: MALTVTKTSNWTIEDSEQLYRIQGWGEPYFGINAAGHVTVSPKGDRGGSLDLYELVQALQQRNISLPLLLRFSDILEDRIERLNACFARAIARYGYQGAYKGVFPIKCNQQRHIIEALVRFGQSHQFGLEAGSKPELLIALAMLNTPGALLICNGYKDRSYIETAILARRLGHTSIIVLEQPEEVAEVIAVSQALGIEPIVGVRAKLSTQGVGRWGTSAGDRAKFGLTVPEILTAVEQLRAAGMLNALQLLHFHIGSQISAISVIKDAIREAGQIYGELVRLGANMQYLDVGGGLGVDYDGSKTNFHASKNYSMQNYASDVVAGIKDACRQRGIPDPTLISESGRAIASHQSVLIFNVLGVSEVPKITPEPATAEEHLIIRNLYDTYQAIDENNYQEAYNDALQFKGEAISLFNFGYLSLPERARAESLFWACCAKILGIARQQEYVPDDLEDLEKIMASIYYINLSVFQSVPDSWAIDQLFPIMPIHRLDEEPTERGILADLTCDSDGKIDQFIDLRDVKSVLELHPFRPGEPYYLGLFLNGAYQEIMGNLHNLFGDTNAVHIRLTPKGYEIEHLVRGDTMQEVLGYVQYQGDALLEKIRCRTEAALAEEQITLAEAQHLLENYERSLRSYTYLSS
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.