PharMolix/UniProtQA huggingface dataset:
Protein: RPAB1_CANGA
Sequence: MDQENDRSISRLWRTFRTVKEMVRDRGYFIAQEELDLTLEDFKVKYCDSMGRAQRKMMSFQANPTEESMTKFPDMGTLWVEFCDEPSVGVKTMKTFVIHIQEKQFQTGIFIYQNNITPSAMKLVPSIPPATIETFHEAALVVNITHHDLVPKHIRLNEEEKAELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETAGRYASYRICM
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  Pols are composed of mobile elements that move relative to each other.  In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template.  Seems to be the major component in this process (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerases I, II, and III subunit ABC1.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KCY_UREU1
Sequence: MKKYINVAIDGPSGSGKSTAAKGLANKLGFLYINTGLMYRAYAYFLNENNLDINTNETACIEAIKNARFIFNGDDVKIDDQDVSDILRSNDVAMLASVVAANAKIRNLATNEQRKIASENNVVMDGRDIGSIVLVDADLKFYLNTSIQTRAKRRLAQNKDIEKLDYESIYNDIKERDYRDMTRDIAPLKKAIDAIEIFNDNMNLDQCVAHLYEIYLNKIKKS
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR15_PAUCH
Sequence: MPLDTTTKQKLINVHQTHSTDTGSVEVQVAMLTERISKLSGHLQQNKHDFSSRQGLLKMIGRRKRLLNYLRSLGEDRYSQLINKLGIRG
What are the official names of this protein?
30S ribosomal protein S15, organellar chromatophore.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore.
Protein: PGKB_LEIME
Sequence: MSLVLKKSIDDVALKDKKVLIRVDFNVPVKNGEITNDFRIRSALPTIQKVLKEGGSCILMSHLGRPKGARMSDPKPEKGVRGYEEAATLRPVAARLSELLEEKVAKAPDCLNASIYVSKLKRGDVLLLENVRFYTEEGSKKEEEADAMAKVLASYADLYVSDAFGTAHRDSATMTGIPKVLGSGYAGYLMEKEINYFSRVLNNPPRPLVAIVGGAKVSDKIELLDNMLGRINYLVIGGAMAYTFQKAQGRKIGISMCEEDKLDLAKSLLKKAQERGVQVLLPVDHVCNKEFKAVDSPLVTEDVDVPDGYMALDIGPKTIHMYEEVIGRCKSAIWNGPMGVFEMPCISKGTFAVAKAMGTGTQKDGLLSIIGGGDTASAAELSARAKNMSHVSTGGGASLELLEGKTLPGVAILTDKQ
What are the official names of this protein?
Phosphoglycerate kinase, cytosolic, Phosphoglycerate kinase B.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF44_HUMAN
Sequence: MRPWALAVTRWPPSAPVGQRRFSAGPGSTPGQLWGSPGLEGPLASPPARDERLPSQQPPSRPPHLPVEERRASAPAGGSPRMLHPATQQSPFMVDLHEQVHQGPVPLSYTVTTVTTQGFPLPTGQHIPGCSAQQLPACSVMFSGQHYPLCCLPPPLIQACTMQQLPVPYQAYPHLISSDHYILHPPPPAPPPQPTHMAPLGQFVSLQTQHPRMPLQRLDNDVDLRGDQPSLGSFTYSTSAPGPALSPSVPLHYLPHDPLHQELSFGVPYSHMMPRRLSTQRYRLQQPLPPPPPPPPPPPYYPSFLPYFLSMLPMSPTAMGPTISLDLDVDDVEMENYEALLNLAERLGDAKPRGLTKADIEQLPSYRFNPDSHQSEQTLCVVCFSDFEARQLLRVLPCNHEFHTKCVDKWLKANRTCPICRADASEVPREAE
What are the official names of this protein?
RING finger protein 44.
Protein: MTMR2_MOUSE
Sequence: MEKSSSCESLGAQLPAARLPSEDSLSSASTSHSENSVHTKSASAISSDSISTSADNFSPDLRVLREANKLAEMEEPALLPGENIKDMAKDVTYICPFTGAVRGTLTVTSYRLYFKSMERDPPFVLDASLGVISRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNGLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPTIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKKTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHSRYKELLAKRAELQRKVEELQREISNRSTSSSERASSPAQCVTPVQTVV
What is the function of this protein?
Phosphatase that acts on lipids with a phosphoinositol headgroup (PubMed:12045210, PubMed:16399794).  Has phosphatase activity towards pho sphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate (PubMed:12045210, PubMed:16399794).  Binds phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate (PubMed:12045210, PubMed:16399794).  Stabilizes SBF2/MTMR13 at the membranes (PubMed:23297362).  Specifically in peripheral nerves, stabilizes SBF2/MTMR13 protein (PubMed:23297362).
What are the official names of this protein?
Myotubularin-related protein 2, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome membrane; Peripheral membrane protein. Cytoplasm, perinuclear region. Cell projection, axon. Endosome membrane; Peripheral membrane protein. Note=Partly associated with membranes (PubMed:14530412, PubMed:23297362). Localizes to vacuoles in hypo-osmotic conditions (PubMed:16399794).
Protein: RNH2_MAGMM
Sequence: MRHKAHPGPDLELECALLRSNRAIKTLCGVDEAGRGPLCGPVVAAAVVLDLDNLPVGLNDSKQLSAKKREQLFEQIYVTSQVGVGEASVAEIDALNILHASMLAMVRAVTALQGRLVVDHALIDGNRVPATLPVPGQAVVKGDAKSLSIAAASIIAKVTRDRIMAELDRDYPHYGWAKSQGYPTQAHLQALALHGVTPHHRRSFKPVKQLLPH
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_XANC8
Sequence: MAKGKRDKIRMISSAATGHFYTTDKNKKNTPGKMEMMKYDPVVRKHVMYKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: DNAK_YERPN
Sequence: MGKIIGIDLGTTNSCVAIMDGTKARVLENSEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEAQRDKDIMPYKIIAADNGDAWLEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKEVGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLVEEFKKDQGMDLRTDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADGSGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIQDVILVGGQTRMPMVQKKVADFFGKEPRKDVNPDEAVAIGAAVQGGVLSGEVKDVLLLDVTPLSLGIETMGGVMTPLITKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAQDNKSLGQFNLDGIQPAPRGMAQIEVTFDIDADGILHVSAKDKNTGREQKITIKASSGLNEEEIQKMVRDAEANAEADRKFEELVQTRNQADHLIHGTRKQLEEAGDKLPAEDKTAIEEAMKGLEAALKGEDKAEIEAKTQALVQVSGKLLEMAQQQQAAAGGDAGDTSAKKEDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PIG2_CLAP2
Sequence: MESTIPAKPDFSNKVFAKDERFWLNYLEGRPTAPKSFFDRIYRYHEEHRGHFGTVHDVGAGNGPYAKELRLKFSHVIVSDIAAENVTLAQERLGNDGFQYRVSRLEDADDIPPGSVDMVFATNVLHFCDQDVAMRALARQLRPGGTFACASFGSAYFADEKVQEIYTRIGRAGARLLLKTLDDPERLLRAMDRTDGTYNVAPLDEKLFMPGAQRVDLNMPERGMLSPLPPEMEVTERDESHTRPSDVLIQEEEDEWKFSMNIGQIKAHIESFPFGKDVATELSPLWREMENLVQDRRIDGHWPAKIILATRADASVE
What is the function of this protein?
Methyltransferase; part of the ergochrome gene cluster responsible for the typical purple-black color of the ergot sclerotia (PubMed:28955461).  The ergochrome gene cluster produces several ergot pigments including the yellow ergochrome secalonic acid and its derivatives, as well as the red anthraquinones endocrocin and clavorubin (PubMed:28955461).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) CPUR_05437 (By similarity).  The atrochrysone carboxyl ACP thioesterase CPUR_05436 then breaks the thioester bond and releases the atrochrysone carboxylic acid from CPUR_05437 (By similarity).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (By similarity).  The next step is performed by the anthrone oxygenase CPUR_05434 that catalyzes the oxidation of emodinanthrone to emodin (By similarity).  Emodin is further modified to yield monodictyphenone via several steps involving CPUR_05427, CPUR_05428, CPUR_05429 and CPUR_05430 (By similarity).  The short chain dehydrogenase/reductase CPUR_05418 then catalyzes the C-5 ketoreduction to give the xanthone skeleton of the monomeric units (PubMed:32105084).  Ergochromes formation requires further dimerization steps of different xanthone units, probably catalyzed by the cytochrome P450 monooxygenase CPUR_05419 (PubMed:28955461).  CPUR_05425, CPUR_05426 and CPUR_05431 are unique to Claviceps, thus it is likely that they are involved in further modification of xanthone units or in their dimerization (PubMed:28955461).  The yellow ergochromes and the red anthraquinone pigments endocrocin and clavorubin are products from the same PKS derived precursors and the latter are likely shunt products in the pathway of xanthone biosynthesis (PubMed:28955461).  It is proposed that atrochrysone carboxylic acid released from the PKS CPUR_05437 can also be converted to endocrocin anthrone which is further oxidized into endocrocin by CPUR_05435 (By similarity).  Endocrocin could be then modified to clavorubin, possibly by CPUR_05423 and CPUR_05431 (PubMed:28955461).  Clavorubin is the principal anthraquinone metabolite produced by the cluster with a much higher yield compared to endocrocin (PubMed:28955461).
What are the official names of this protein?
Methyltransferase CPUR_05424, Ergochrome gene cluster protein CPUR_05424.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: RNPH_SHESR
Sequence: MRPSNRTPAQTRPITITRQFTAHAEGSVLVEFGETKVLCTASFTEGVPRFLKGQGQGWVTAEYGMLPRSTHSRMDREAARGKQSGRTQEIQRLIGRALRACVDMKALGENTIVIDCDVIQADGGTRTASITGACVALVDALNWARGKGIIKSNPLKFLIAAVSVGIYNGEAISDLEYVEDSAAETDMNVVMTETGKIIEIQGTAEGEPFSHEELIELLGLAKNSIREIVDVQKAALN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: TRPA_METKA
Sequence: MSGLVLERIFEEAEGEGRGALIGYLTCGHPGLEETVSLARALRDGGVDILELGVPFSEPIADGPTIQKAVDEALRAGTTPWDCLEVAEEVSEFVPVVLLCYYNTLHANGFERYLSAAAEAGVSGIIVADMPVEESDEVHSVARDLEIDVIYLVAPSTTDERLKKIGERASGFVYVISRYGVTGARRDLSEDTLELVRWVRDHVDVPVAVGFGISERWHVEEVIAAGADGAIVGSAFIKEIHRSEDIAEAEERVRELAKELVEGARDGYRRRSSSE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: Y2619_SHESM
Sequence: MQYPVDTHTHTVASTHAYSTIHDYLAVAKQKGIRLFATTDHGPAMADAPHFWHFVNLRVLPRMVDGVGILRGIEANIKNREGEIDYFGDYLSQLDIVLAGFHEPVFPPSDKATHTEAMINAIKSGKVDIITHPGNPAYPIDIEAVAAAAAEYGVALEINNSSFEVSRKGSEANCTAIAKAAKELGATLVMGSDSHVAFSLGGFDRALSIIEAVDYPKDKLLNRSPMALLNFLAQRGHKSVADLMPLFSDDIA
What are the official names of this protein?
Probable phosphatase Shewmr4_2619.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: SYDND_THEFY
Sequence: MIRTHEAGTLRADHAEQNVVLAGWVARRRDHGGVVFLDLRDASGIVQVVVREDELAHDLRSEYCIKVTGTVRIRPEGNENPDIATGEIEVVASHIEVLSESAPLPFPLDGNQEISEEARLRYRYLDMRRPETAEALRVRSRATYIAHEVMNDNGFVYVETPYLTRSTPEGARDFLVPVRLQPGHWYALPQSPQLFKQLLMVGGMERYYQLTRCFRDEDFRADRQPEFTQIDIEMSFVDEEDLFDIGEKLFTRLLREVRGVELPRPFRRMKFAEAMDRFGTDKPDLRFGQELVELTDFFANTPFRVFQAPYVGAVVMPGGASQTRRELDAWQEWARSRGAKGLAYVLVHEDGTLGGPVAKNLSEEERAGLAERVGAKPGDAIFFSAGERTASQELLGAARLEIGKRCGLIDESAWEVLWITDMPMFEKDDEGGWTSVHHPFTAPAQEVADTFHNDPGSATARAFDLVMNGYELASGSIRIHRAEMQQRVFDTIGLSKDEAETKFGFLLEAFQFGPPPHGGLAVGWDRLVMLLAGQSTIRDVIAFPKTASGADPLTGAPTPITAEQRREAGVDAVPEQATS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGF_PANTR
Sequence: MSMLFYTLITAFLIGTQAEPHSESNVPAGHTIPQAHWTKLQHSLDTALRRARSAPAAAIAARVAGQTRNITVDPRLFKKRRLRSPRVLFSTQPPPEAADTQDLDFEVGGAAPFNRTHRSKRSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKAVRRA
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity).  The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse.  In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro) (By similarity).  Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI (By similarity).  Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer.  The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Beta-nerve growth factor, Beta-NGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted. Endosome lumen. Note=ProNGF is endocytosed after binding to the cell surface receptor formed by SORT1 and NGFR.
Protein: YCEH_SALHS
Sequence: MKYELTATEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLTEQEVQEQLDNLVKRHFLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALVTTLLLRGAQTPGELRSRASRMHEFSDMTEVESTLERLASREDGPYVVRLAREPGKRESRYMHLFCGDVDELSLQTSAPESASGDLQSRVEALESEVAELKQRLDSLLAHLGE
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: RBFA_RHOPA
Sequence: MSRQHQKSSPPGGSTRSLRVGELIRHAVAEILAQGGVHDPVLESHLVTVPEVRMSPDLKLATIYVMPLGGRDEKLVIDALEHHKRFLRGEIAHRVNLKFAPELRFRIDERFAEAERIDKLLRSPAVQKDLEPNSDQD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E4PD_PSEA6
Sequence: MIRVAINGFGRVGRNVLRALYETGQNKQIQIVAINELAEPEGVAHLLKYDTAHGRFRFPVVLDNQQLVVAGDHITLLQQENIRDLPWAQLDIDVVLECTGVNNERVHGEQHIAQGAKKVLFSQPCGPDVDATIIMGINEESLKASDSIVSAGSCTTNCIVPVIQVLDEAFSVSSGTITTIHSSMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLARGIERVLPKFAGKFEAIAVRVPTINVSAMDLSVTLDAKVTIDDVNQALKTVKNGRLNGILDFTEEPLVSVDFNHDAHSCIVDGTQTRVSHKQLVKLLVWCDNEWGFSNRMIDIVLVMNTLSLGNTGK
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO11_METMA
Sequence: MELNILNKTNNELEVELRGETHTLLNLLKDLLIKDERVVTAFYDMKYVSISDPVLYIKTDGADPILVLKDVVAIIVSECDEFIDVFSKAANA
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1M_DROMD
Sequence: MEFILSLIGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALIGFKILLFSLL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VA0E1_RAT
Sequence: MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit e 1, V-ATPase subunit e 1, D-serine-regulated transcript 1 protein, DSR-1, V-ATPase 9.2 kDa membrane accessory protein, V-ATPase M9.2 subunit, Vacuolar proton pump subunit e 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase e1/e2 subunit family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DER_MACCJ
Sequence: MTKPTIAIVGRANVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHEFNIIDTGGIELGDEPFQEQIRAQAEIAIEEADVIIFMVNGRDGITNEDDFVAKLLFKSSKPVVLGVNKIDNPEMRADIYEFYSLGFGEPFPISGSHGLGIGDLLDEAAKHFPEQQEEDYDDDVIKFSLIGRPNVGKSSLINAILGEERVIVSPVAGTTRDAIDTVYTFENQEYVMIDTAGMRKKGKVYEATERYSVLRALKAIERSNVVLVVIDAEEGIIEQDKKIAGYAHEAGKAIVIVVNKWDTVEKDSKTMKKFEDKVRENFQFLDYAPIAFVSAKERKRLNTLFPLINMAGENHRKRVQSSTLNEVITDAVAMNPTPTHKGSRLNIFYTTQVAIEPPTFVFFVNDVEMMHFSYQRFLENRIRAAFGFEGTPLHLIARKRN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: YTM1_BOTFB
Sequence: MAQGQVQVHFSTTSPDIELPEGKQQLLVPTNVRRYGLSQILNSEAMLDTSSPIPFDFLINGTFLRTTLDEYLTANGLSSETTLNLQYVRSLIPPLYEASFEHDDWVSSVDVLSGSSAAGAWGKNSIVEGQERILSGSYDGLLRVWNKSGQAIATSAPASIGGHTSGVKAAKWLSARQVASAGLDRTIRIWNYSESEDHFSAQLKPTMELYGHTGSIDSIAVHGPSNRILSASADGQIGFWTSHKSSAPEVNTSLISGPSTKRRKITTSTSTPQRGPLSLMDCHNGPATAVIFNPQDPTVAYSASQDHTIKTLDITTSSIVDTRTLLNPILSLSALPGIGHQIIAAGTTARHIALIDPRASAATTQAMTLRGHTNFVSSIFADPDSNYGLVSAGHDGTCRVWDLRSTRQGTKDEGLGVVGEAVYIIERESRKDKTTKTVGGEGVKVFDVNWDKDVGIVSAGEDKMVQVNRGRGVTRPEN
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ytm1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: GPR82_HUMAN
Sequence: MNNNTTCIQPSMISSMALPIIYILLCIVGVFGNTLSQWIFLTKIGKKTSTHIYLSHLVTANLLVCSAMPFMSIYFLKGFQWEYQSAQCRVVNFLGTLSMHASMFVSLLILSWIAISRYATLMQKDSSQETTSCYEKIFYGHLLKKFRQPNFARKLCIYIWGVVLGIIIPVTVYYSVIEATEGEESLCYNRQMELGAMISQIAGLIGTTFIGFSFLVVLTSYYSFVSHLRKIRTCTSIMEKDLTYSSVKRHLLVIQILLIVCFLPYSIFKPIFYVLHQRDNCQQLNYLIETKNILTCLASARSSTDPIIFLLLDKTFKKTLYNLFTKSNSAHMQSYG
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 82.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRAZ_CHLTE
Sequence: MPGFIGREQHSVDEKGRLLIPARFRRRFLLQENDPATGAPSRSPVLYVFKADDGSLELYEPSVWSEKEQQLLKLSDFNPDERLLTTMIYARLDQTELDRSGRIALSREMLDHAGIVKDAVIIGANAKMTVWEPLRLERLLSDNASRFAPLANRYI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DARG_THEA5
Sequence: MLRFVRGNLLEAPVEALVNTVNTVGVMGKGVALQFKRAFPDNYQAYVKACERGQVQIGRIFVYDRGPLAQPRYIFNFPTKKHWRHPSRMEYVEEGLKDLVCRIQELRVRSIALPPLGAGNGGLPWPEVKQRIQEALEALEGVEVWVYEPVENPKAHSIVPLKTKPRLTPARAALLKLFGLYGALGEPLGRLEAQKLAYFLQEAGLDLKLDFACKQFGPYAEPLNHVLARLEGHYIQGFGDRTGISQIRLKPQALDEAVLFLADYPKADEAATRAADWVKGFETPYGLELLATVHWAVRHEGARDWASLQKRLQAWNPRKATFPKTHLQVALDALLKRGALRPEEWQDRPPKLPANVAQEA
What is the function of this protein?
Antitoxin component of a hybrid type II/IV toxin-antitoxin (TA) system.  De-ADP-ribosylates DNA modified on thymidine by its cognate toxin DarT, which neutralizes the activity of cognate toxin DarT.  Upon expression in E. coli neutralizes the effect of cognate toxin DarT (PubMed:27939941).  Upon expression in M. tuberculosis neutralizes the toxic effects of endogenous DarT (PubMed:32634279).
What are the official names of this protein?
DNA ADP-ribosyl glycohydrolase, DarG, Antitoxin DarG.
What is the protein family that this protein belongs to?
Belongs to the DarG ADP-ribosyl glycohydrolase family.