PharMolix/UniProtQA huggingface dataset:
Protein: BST1_ASPOR
Sequence: MHRRSSGSPVEDDAEDSLSSRIPPEPSNGPNVVDTPEKSRSQVARTGTSIDLRRDATGASTPRSRNSSMWRTPPSSSMTSNPPDCKSSSVMMPLASQRLPIEASPDHQRRYRPSRLRSPWPCSILTAFTTLVASIFLFFILRSFALRQTGGDGCGVPVMSPTFIRMVGFDTEHTRFASKYNLYLYREGGVDPYSQENLGLNGVPVLFLPGNAGSYRQVRSLAAEASRHYYDVVRHDEDRLNAGTRSLDFFMIDFNEDMAAFHGQTLLDQAEYVNEAVAYILSLYHDPRRSRRDPELPDPSAVVLVGHSMGGIVARTALTMTNYQANSVNTIVTMSAPHAKPPVSFDSDIVQTYKQINDYWREAYSQTWANDNPLWHVTLISIAGGSRDTVVPSDYASISSLVPETHGFTVFTSTIPDVWIGMDHLSITWCDQFRKAIIKSLFEVVDVRRATQTKPRAERMRIFKKWYLTGMETVAERTLPRKGVSGKKFTLLTNQQFDKSGDHGSLEVLFCSVFPLQNGKPATAFSMNMDFSGGTSGSTRLACKNAAEDGIHLPASTPSSKRPYDRVQPFSYLQYDLEDLAEHQFVAVVDKANSPTKGFVLAEFSDSSDSVIRARLGLGSLLSAGLKVRLPANRPMLTELQIPAVHSSLLDYRLKIIRKNHGQQQELFAPLLRQSVADPHESKFFVNVKNVNVNLHGLAPFMPPPLREQATLGGVSFHLWTDPSCDSTIDISLSVDIAGSLGELVMRYRTVFAAFPLLVVALVMRKQFQVYDETGYFITFAEGLDSALRSSLPMLLLAMSLLASSLATSTKLPPTDDPFHWRTNSTESPIDFTKNDLLLGSQDAFFWFLVPIFGLISVGVCLVINYVALALIFLLTSIYGFLRSKSGYIRRDEKGNLPIFSSASPRRRLVNSAILLALVSTVIPYQFAYMVACIVQLATSVRASWHAKEAKSTTHYNFANFAYSIFLLMLWILPINALVLLVWAHNLVVHWFMPFSSHHNVLSIMPFVLLVEAMTTGTMIPRVTTRFKHVTSMLFFFIAIYSAIYGVSYAYLLHHLTNILAAWLVGIYFSASGFSLSRLWRVLEGDEAVQNPASGSHTKKKP
What is the function of this protein?
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
What are the official names of this protein?
GPI inositol-deacylase.
What is the protein family that this protein belongs to?
Belongs to the GPI inositol-deacylase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: VAC8_ASPOR
Sequence: MSGIASACLSCLSTVDRWCHITACLGPIGGRSRDGIYETTLADNEREAVSDLLGYLENRAETDFFRGEPLSALSTLVYSDNVDLQRSASLTFAEITERDVREVDRDTLEPILFLLQSSDIEVQRAASAALGNLAVNADNKVLIVALGGLAPLIRQMMSPNVEVQCNAVGCITNLATHEDNKAKIARSGALGPLIRLAKSKDMRVQRNATGALLNMTHSDDNRQQLVNAGAIPVLVQLLSSSDVDVQYYCTTALSNIAVDASNRKRLAQTESRLVQSLVHLMDSSTPKVQCQAALALRNLASDEKYQLEIVRAKGLPPLLRLLQSSYLPLILSAVACIRNISIHPLNESPIIDAGFLKPLVDLLGSTDNEEIQCHAISTLRNLAASSDRNKELVLQAGAVQKCKDLVLKVPLSVQSEMTAAIAVLALSDELKPHLLNLGVFDVLIPLTESESIEVQGNSAAALGNLSSKVGDYSIFVRDWADPNGGIHGYLKRFLASGDPTFQHIAIWTLLQLLESEDKRLISYIAKSDDVVHMVKSISDKNIESDEEDQEDGEGEVIALARRCLEFLGNGPRQTLVEA
What is the function of this protein?
Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
What are the official names of this protein?
Vacuolar protein 8.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Vacuole membrane; Lipid-anchor.
Protein: RL21_MYCGA
Sequence: MFAVIASGSKQYRVKLNDEIYVEKLNSQVGEKIVFDKVYFVNNTFGKPFVKGASVTCEVLKQGRQKKINVIKHISQKHHLKKYGHRQPYTKLKVVAINHG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: HUTI_BACC1
Sequence: MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQSSKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWSTATI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_ECOL5
Sequence: MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGTQLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHDLSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTNWVKELDA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NLTP_LYCBA
Sequence: GPLGGCCGGIKKSAAAGISGINYGIAAGLPGKCGVNIPYKISPSTDCSKVQ
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).
What are the official names of this protein?
Non-specific lipid-transfer protein, LTP.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: HIBCH_CHICK
Sequence: MAARVLMAPRRLKPFNRLQVILQHLKTCKHTDSAADVLLQKQGGAGIITLNRPKVLNALSFKMIQQIYPQIKAWEQDPETFLIIIKGTGEKAFCAGGDVRAIADAGKAGDTMTRDYFREEYRLDNAIGTCKKPYVALIDGITMGGGVGLSVHGHFRVATEKTVFAMPETAIGLFPDVGGGYFLPRLSGKIGHLLALTGFRLKGRDVLKAGIATHFVESGKLPELEKDLIALKSPSKENIADLLNSYHMQTKIDQEKEFVLDEHMERINSIFSANSMEEIVQKLKQDGSPFATKQLEAINKMSPTSLKLTLRQLREGATMSLQDVFTMEYRLSQACMRGHDFYEGVRAVLIDKDQSPRWKPAALEEVSDEFVDNCFKPLGNNDLKL
What is the function of this protein?
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite.  Has high activity toward isobutyryl-CoA.  Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.  Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity).
What are the official names of this protein?
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, 3-hydroxyisobutyryl-coenzyme A hydrolase, HIB-CoA hydrolase, HIBYL-CoA-H.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CDN2D_HUMAN
Sequence: MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL
What is the function of this protein?
Interacts strongly with CDK4 and CDK6 and inhibits them.
What are the official names of this protein?
Cyclin-dependent kinase 4 inhibitor D, p19-INK4d.
What is the protein family that this protein belongs to?
Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RECF_RICAE
Sequence: MKNIFLHSLSLENYRNFKNLELKTDNTPIILIGENGSGKTNILEAISLFYPGRGLRSAKLANVCKTSEDHCLVKALLQSKLGLAEFTTQFKRSSNRRITEYNESKIANNELSKFTSMVWLTPHMEGIFTSGSSDRRKFLDRIVYNFDPKHAELVSKYEYYMHERNKILVEDIRDDNWLKIIEEKMADISNHIANNRLKTLEFMQQAIDDLENEFPKADLSIDGIVEQKILNGKKNIVSFITAELYQTRSKDKLLGRTSFGVHKSDFLVKHQKKNILAKFCSTGEQKAILIAIILAEMNYAIKLTKIAPILLLDEVFVHLDDKRRQYLIEFLIGLNMQLWVTTTNLEGIENFATKAQLIKL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_PHOV8
Sequence: MSSNTENQRVNFASIKNPMKYPDFLEVQLKSFQDFLQLDTPPEKRKNDGLYKVFAENFPIADTRNNFVLEFLDYYIDPPHYSIDECLERGLTYSVPLKAKLKLYCTDPDHEDFDTVIQDVYLGPIPYMTPKGTFVINGAERVVVSQLHRSPGVFFGQSVHANGTKLYSARIIPFKGSWIEFATDINNVMYAYIDRKKKLPVTTLLRAVGFENDKDILEIFNLAEDVKVNKTNLKKVVGRKLAARVLKTWTEDFVDEDTGEVVSIERNEVIIDRETVIEEDHIDEIIDSGVQNILVHKEEANSSDYSIIFNTLQKDPSNSEKEAVLYIYRQLRNADPADDASAREVINNLFFSEKRYDLGEVGRYRINKKLGLTTDMDVKVLTKQDIIEIIKYLIELINSKADVDDIDHLSNRRVRTVGEQLSNQFAIGLARMSRTIRERMNVRDNEVFTPIDLINAKTISSVINSFFGTNALSQFMDQTNPLAEITHKRRLSALGPGGLSRERAGFEVRDVHYTHYGRLCPIETPEGPNIGLISSLCVYAKINELGFISTPYRKVADGKVDISDEGIEYLTAEEEEDKIIAQGNAPLDDEGKFVREKVKARRDADYPVVTPDQVELMDVSPQQIASIAASLIPFLEHDDANRALMGSNMMRQAVPLLRTEAPIVGTGIEKQLVEDSRTQIAAEGDGVVEYVDATTIRILYDRNEDEEFVSFEPALKEYRIPKFRKTNQSMTIDLRPTCDKGQRVKKGDILTEGYSTQGGELALGKNLLVAYMPWKGYNYEDAIVLNERVVREDLLTSVHVDEYILEVRETKRGMEELTSDIPNVSEEATKDLDENGIVRVGARIEPGDILIGKITPKGESDPSPEEKLLRAIFGDKAGDVKDASLKASPSLRGVVIDKKLFSRVIKSRSEKNADKAILPKLNDEFEEKAAKLKDILIEKLLVLTNGKVSQGVKDYLGTEVIAKGAKFTKRDLESLDYTIIQLSKWTADAHKNDMIRDLVMNYLKKYKELDAELKRKKFAITIGDELPAGIIQMAKVYIAKKRKIGVGDKMAGRHGNKGIVSRVVRQEDMPFLADGTPVDIVLNPLGVPSRMNIGQIFEAVLGRAGKELGVKFATPIFDGASMDDLNEWTDKAGLPRYCKTYLCDGGTGERFDQPATVGVTYMLKLGHMVEDKMHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAFGAAHILQEILTIKSDDVVGRSKAYEAIVKGEPMPTPGIPESLNVLLHELRGLGLSINLE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: DRG1_MOUSE
Sequence: MSGTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK
What is the function of this protein?
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP.  Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions.  When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation.  Binds to microtubules and promotes microtubule polymerization and bundling that are required for mitotic spindle assembly during prophase to anaphase transition.  GTPase activity is not necessary for these microtubule-related functions.
What are the official names of this protein?
Developmentally-regulated GTP-binding protein 1, DRG-1, Neural precursor cell expressed developmentally down-regulated protein 3, NEDD-3, Translation factor GTPase DRG1, TRAFAC GTPase DRG1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes.
Protein: Y6921_MYCS2
Sequence: MAQSEDPEDFIAPAAHRVRPGTLLLANTDLLEPTFRRTVIYIVEHNSGGTLGVILNRPSETAVYNVLPQWAEVTAKPKTMFIGGPVKRDSALCLATLRVGMQADGVDGLRHVQGRVVMVDLDADPEELAPVIEGVRIFAGYSGWTTGQLDGEIERDDWIVLSALPSDVLIEPRIDLWGRVLRRQPLPMSLLATHPIDVSRN
What are the official names of this protein?
UPF0301 protein MSMEG_6921/MSMEI_6732.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: PAND_CORGB
Sequence: MLRTILGSKIHRATVTQADLDYVGSVTIDADLVHAAGLIEGEKVAIVDITNGARLETYVIVGDAGTGNICINGAAAHLINPGDLVIIMSYLQATDAEAKAYEPKIVHVDADNRIVALGNDLAEALPGSGLLTSRSI
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MXIG_SHIFL
Sequence: MSEAKNSNLAPFRLLVKLTNGVGDEFPLYYGNNLIVLGRTIETLEFGNDNFPENIIPVTDSKSDGIIYLTISKDNICQFSDEKGEQIDINSQFNSFEYDGISFHLKNMREDKSRGHILNGMYKNHSVFFFFAVIVVLIIIFSLSLKKDEVKEIAEIIDDKRYGIVNTGQCNYILAETQNDAVWASVALNKTGFTKCRYILVSNKEINRIQQYINQRFPFINLYVLNLVSDKAELLVFLSKERNSSKDTELDKLKNALIVEFPYIKNIKFNYLSDHNARGDAKGIFTKVNVQYKEICENNKVTYSVREELTDEKLELINRLISEHKNIYGDQYIEFSVLLIDDDFKGKSYLNSKDSYVMLNDKHWFFLDKNK
What is the function of this protein?
Involved in the secretion of the Ipa antigens.  Involved in the intracellular dissemination of Shigella.  Part of the Mxi-Spa secretion apparatus.
What are the official names of this protein?
Protein MxiG.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Cell outer membrane; Single-pass type II membrane protein.
Protein: RL20_ECO81
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: GLMU_SYNP6
Sequence: MVAVAILAAGKGTRMKSQLPKVLHRLGSQTLLDRVLASLTPLNVDRCFVIVGYQGDRVRESWAHRTDIEFVEQTQQLGTGHAVQQLLPHLKGYQGDLLVLNGDVPLLRGETLEALVSGHQRSGAAATLLTAQLNQPKGYGRVFCDATSRVCEIIEDRDCTPAQRQNPRVNAGVYCFRWPDLEAVLPNLSTANDQQEYYLTEAITYLDPVSAVEVADSQEILGINDRLQLADSFRILQERIRQQWMLAGVTLVDPTSITIDETVQLGTDVVIEPQTHLRGNTVIGNNCSIGPNSLITNSQIGDGVTVQMSVISDSTIAANSKIGPFAHLRGAAAIGEACRIGNFVEVKKSTVGDRTNVAHLSYLGDATLGQRVNVGAGTITANYDGVSKHPTVIGDRSKTGANSVLVAPVTIGQDVTIAAGSTINKDVPDGALAIARSRQTIHENWSTPTTEQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_ECOBW
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: APT_ECOK1
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWC5_KLULA
Sequence: MSDTKGSDLNEDSALEFDEESYHESEDEDFDPSKEQNKRKTTNDNKKTDVNANISDSDQDEDEDEEYDEEAQEEEKKYSSIVSESGGLIKTRRARLQEEHDALKNKYEQIDIAETSGKSNDLWRQLKERALSRSQFNGSVMDQDAGSITDSMQEQKILIERTYKFAGEVIKEKKWVLRHSAEGQEYLNSIKFKTGTLDKNTVPPDTVKNTQAQQTEGKQNRVNEAGRLLKRHLKRPPILEQIIAGNLKPKLTTLEKSQLDWASYVDKEGIHEELNLHNKDGFLAKQDFLNRVESSKDQKYRELRKLQLQTEQQKQ
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
SWR1-complex protein 5.
What is the protein family that this protein belongs to?
Belongs to the SWC5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LAG1_SCHPO
Sequence: MSNRKADEKHHMSSSSLTNDRSYIRNLSNRKTSISRKVPITRTLEDPSNFVAKDGTKLVQAPLFLLVWQKEICLSIIAICFACLLSPSLRPYAEPFIFLSYKQPDGSYGKGPKDACFPIFWVIVFTAFRVIVMDYVFRPFVLNWGVRNRKVIIRFCEQGYSFFYYLCFWFLGLYIYRSSNYWSNEEKLFEDYPQYYMSPLFKAYYLIQLGFWLQQILVLHLEQRRADHWQMFAHHIVTCALIILSYGFNFLRVGNAILYIFDLSDYILSGGKMLKYLGFGKICDYLFGIFVASWVYSRHYLFSKILRVVVTNAPEIIGGFHLDVPNGYIFNKPIYIAFIILLFTLQLLIYIWFGMIVKVAYRVFSGEEATDSRSDDEGEDEEASSTNEDK
What is the function of this protein?
Component of the ceramide synthase complex required for C26-CoA-dependent ceramide synthesis.  Facilitates ER-to-Golgi transport of GPI-anchored proteins (By similarity).  Involved in the aging process (By similarity).
What are the official names of this protein?
Sphingosine N-acyltransferase lag1, Longevity assurance factor 1, Longevity assurance protein 1.
What is the protein family that this protein belongs to?
Belongs to the sphingosine N-acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YGAC_ECO57
Sequence: MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARMGRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVALERYLNGLFGEAS
What are the official names of this protein?
Uncharacterized protein YgaC.
Protein: GAPN_SCEVA
Sequence: LAIPPFNYPVNLAVSKLAPALMAGNTVVLKPPSQGVVAGIHMIKCFQAAGLPAGTVNLVTGKGSEIGDFLTTHPAVNCISFTGGDTGIAISRKAGMVPLQMELGGKDACIVCSDADLDLAATHIIKGGFSYSGQRCTAVKVVLVMQDIADELVRKVHAGVQKLKVGRPEDNADITAVVSEGSANFIQGLVEDAKAKGATFLTDWKREGNLLWPVLLDNVTADMRIAWEEPFGP
What is the function of this protein?
Important as a means of generating NADPH for biosynthetic reactions.
What are the official names of this protein?
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, Glyceraldehyde-3-phosphate dehydrogenase [NADP(+)], GAPDHN, Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase, Triosephosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: TRPA_METMP
Sequence: MNKPVLVSFLVSGDPNPDATLKFMKTLDKYSGVIELGIPFSDPVADGPTIQAADVRSLSNNFKIAKSFEVLKEFRKESDTPVILMTYYNPVYKRGIENFVIQAKEAGANGLIIVDLPLQEATEYRKICKKHEMGTVFLAAPNTPEERLKISDEASTEFLYLISTFGITGARDTFEQMTFDFIKRARTTCKGKICVGFGISKGSHAESLIEQGADGVIVGSAFVDIIKNYGDSKEALVKLEELAKELSEGIDKGYEKRK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RLMN_SYNE7
Sequence: MARSGLEPQTVTDATPLLGRSLPELQDWVVAQGQPSYRAKQLYQWLYERSIHNLAEISVFPKAWRQSLQAVPVGRSQIVDRSVSPSGTIKYLLRLHDGEIIEAVGIPSGDRLTVCVSSQLGCAMACDFCATGKGGFRRHLAPHEIIDQVLTVQEDWQQRVSNIVFMGMGEPLLNLDAVLAAIRCLNQDIGIGQRGITVSTVGIPGHIRRLAETKRVGDRPLQFTLAVSLHAPNQAIRDRLIPSSRHYPITDLLQECRDYVQITGRRVTFEYILLAGLNDQPEQAEQLAQLLRGFQSHVNLIPYNPIDEVEYQRPSKARVDAFADALRQQRVAVTVRWSKGLGADAACGQLRANRSTATLPA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_SALRD
Sequence: MSTLSSEARVVGIDVGTKRVGVAVADPLRLFAQPHGTYAPDEALDVLQALRDADGIARIVVGWPLTEEGTAEEATEMVEAYVERIREALGTVEVAREDERYTSEIAKDLLREAGVSQPGRYDKGRVDAAAAAVILQGFLNRTG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPL_GLOFF
Sequence: MKFFAVFALCVASVSAANLDAIAKPGFPAGRIINGHEADKGEAPFIVSLKAGKGHFCGGSIIAENWVLTAGHCLIFDEFEIVAGLHSRNDESDVQIRKVTGKHQQIVHEKYGGGVGPNDIGLIYVDKPFNLNALTRDGTAAVAKVNLPTGKYESTGKGKLYGWGLDNSGFSPNILNTLDVDIIGYEECKNALNSDDPLDPVNICSYTAGAIDGACNGDSGGPMVRITPDGTELVGIVSWGYQPCASTTMPSVYTWTSAFDKWIEDSIKNYAQLL
What is the function of this protein?
Protein with lectin and protease activity involved in the establishment of trypanosome infections in tsetse flies.  Binds D-glucosamine and agglutinates bloodstream-form trypanosomes and rabbit red blood cells.  Capable of inducing transformation of bloodstream-form trypanosomes into procyclic (midgut) forms in vitro.
What are the official names of this protein?
Lectizyme, Proteolytic lectin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: HIS4_YARLI
Sequence: MTKFRGCIDIHSGQVKQIVGGTLTDSDADLKTNFVATQPPGYFAQLYKDNNVVGTHVIKLGPGCDEAAEEALAGWPDHLQIGGGINHDNAEKWIKLGASHVIVTSFLFPDAKLDMKRLTDLEAILEPYGGKKRIVVDLSCRRKDGKWVVAMNRWQTLTDTEVNKETLEQLAKHCDEFLIHAADVEGLCNGIDEELVTKLGEWLEEGHLPPVTYAGGAKNIDDLALVQKLSHGKVDLTYGSALDVFGGDKVKFSDCVEWNEKMHK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, 5-proFAR isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_MYCLB
Sequence: MSGGAGIPEVPGIDASGLRLGIVASTWHSRICDALLAGARKVAADSGIDGPTVVRVLGAIEIPVVVQELARHHDAVVALGVVIRGDTPHFDYVCNSVTQGLTRIALDTSTPVGNGVLTTNTEKQALDRAGLPTSAEDKGAQAAAAALTTALTLLNLRSRI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: APOA4_MACFA
Sequence: MFLKAVVLTLALVAVTGARAEVSADQVATVMWDYFSQLSSNAKEAVEHLQKSELTQQLNALFQDKLGEVNTYAGDLQKKLVPFATELHERLAKDSEKLKEEIRKELEEVRARLLPHANEVSQKIGENVRELQQRLEPYTDQLRTQVNTQTEQLRRQLTPYAQRMERVLRENADSLQTSLRPHADQLKAKIDQNVEELKERLTPYADEFKVKIDQTVEELRRSLAPYAQDAQEKLNHQLEGLAFQMKKNAEELKARISASAEELRQRLAPLAEDMRGNLRGNTEGLQKSLAELGGHLDRHVEEFRLRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDNTLSLPEPEQQREQQQEQQQEQEQEQQQQQEQQQQQEQQREQQQQEQQQEQQQEQVQMLAPLES
What is the function of this protein?
May have a role in chylomicrons and VLDL secretion and catabolism.  Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT.  Apoa-IV is a major component of HDL and chylomicrons.
What are the official names of this protein?
Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.