PharMolix/UniProtQA huggingface dataset:
Protein: RPOC1_GLOVI
Sequence: MPRMEQRFDYIKISIASPERVMAWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPSKDWECYCGKYKRVRHRGIVCERCGVEVTESKVRRHRMGYIKLAAPVTHVWYLKGIPSYISTLLDMPLRDVEQVVYFNAYVVLNPGNAENLYYKQLLTEDQYIEVEDQIFAEDSSLELPEGWAKMGAEAIHELLAAIEMESEAERLRADLGESKGQKRTKLIKRLRVLDNFIATGSRPEWMVLTAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKLHQCGLPKEMAIELFQPFVIHKLIQRGLVNNIKAAKKMIQRNDARIWSVLDEVITGHPVLLNRAPTLHRLGIQAFEPILVSGRAIQLHPLVCTAFNADFDGDQMAVHVPLSLESQAEARLLMLASNNVLSPATGRPIITPTQDMVLGCYYLTVDNPDATKGSGKYFGSSEDAVIAYNQGMIDLHAKIWLRFEGEVETDNPEDLRVRRDEQGNALSQFVRTTVGRIIFNQVIQETLVAS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit gamma, RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
Protein: HSCA_DELAS
Sequence: MALLQISEPGQSPDPHQRRIAVGIDLGTTHSLVAAVRNGVAECLPDDQGRVLLPSVVRYLPQGRREIGHAAQAALSTDAGNTIASAKRFMGRTLADIDAPEKLPYRFAEQEAGRGVIGIETVDGTKTAVEVSAEILATLRFRAEDTFNDDIHGAVITVPAYFDDAQRQATKDAAKLAGINLLRLINEPTAAAIAYGLDNGSEGVYAVYDLGGGTFDISILRLSQGVFEVVSTGGDSALGGDDYDAALAEWVAQQTGVVPQTAEDKARWRMAARLCKQALTDAQVATLTAELSTGAVHFDVKRSDFDASTAHLTARSLAAVRRALKDAGLARDEVQGVVLVGGSTRMPQVREAVAEFFGRDPLINLNPDEVVALGAAIQANQLAGNSSSGDMLLLDVIPLSLGVETMGGLVERIISRNETIPTARAQDFTTYKDGQTALAVHVVQGERDLVADCRSLARFELRGIPPMAAGAARIRVTFTVDADGLLSVGAKEQTSGVEAHIHVKPSYGLSDDEVARMLQDGFATAQQDMQARALVEARVDADRMLMATESALQADGDVLAADQRAAIDALIDALRASVGSEDAAVIEAATQALAKGTESFAAERMNRSIQQALAGKSVQSLS
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: DXS_SHEON
Sequence: MSLDISQFPVLAQANTPNELRQLPQALLPQLADELREFLLKSVGMSSGHFASGLGTVELTVALHYVYNTPFDRLIWDVGHQAYPHKILTGRRDRMHTIRQKNGLHPFPWREESEYDTFSVGHSGTSISAALAMAVAAEKEQAGRKVVAVIGDGAMTGGMVFEAMNHAGDLHNDMLMVLNDNEMSISENVGALNNHLAQLMSGRFYTTIRESSKKVLKGMPVIKEMAKRTEEHLKGMVVPGTLFEELGFNYIGPIDGHDVDALVETLRNMRNLKGPQVLHIMTKKGRGYEPAEKDPIGWHAVPKFDPSLFKKPATKPGLPTFSQVFGKWLCDIAEQDEKVLGITPAMREGSGMVEFSQRFPKQYFDAAIAEQHAVTLGAGFACEGYKPVVAIYSTFLQRGYDQLIHDVALQRLPVLFAIDRGGIVGADGPTHQGAFDLSFMRCIPNMVIMAPSDENECRQMLYTGYCYDAGPSAVRYPRGSATGATQVEAMTALPIGKGVIKRLGKRIALLNFGTTLAAALTAAESLDATVVDMRFVKPLDVDLVKEMAQTHDVLVTVEENAIMGGAGSGVLELLQQLKMPKPVLQIGLPDEFIKHGSPDEVIHDLQLDAEGMLAQINAYLAN
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: ATE1_ARATH
Sequence: MSLKNDASSSHDGGSNRESVIDDHGRRKSTCGYCKSPARSSISHGLSAQTLTVYDYQALIDRGWRRSGTYLYKHEMDKTCCPPYTIRLKASDFVPTKEQQRVSRRLERFLDGKLDVQPREQRGASSSGDVSDTRRKTLGAAKSEENKKVEAVMDDLSKNIDQAVQLCIRSGEFPSNMQIPKASVKKVFCARRKKLAEGTEQILYTSNIAFPIAAAIKRIQTSEKEGINSAEGNRLSPETISEMLLSAMHKVGETPDVSIKVCKGHINFLSSAKDSFSDRDVVPNGNISRGANSLDGSETLHAKKDSENHQARKRKLEIHLKRSSFDPEEHELYKRYQLKVHNDKPGHVVESSYRRFLVDSPLIDVQPSGDEKVPPCGFGSFHQQYRIDGRLIAVGVVDILPKCLSSVYLFWDPDYAFLSLGKYSAIQEINWVIENQARCPSLQYYYLGYYIHSCSKMRYKAAYRPSELLCPLRFQWVPFEVARPMLDKKPYVILSDIAISHNQCSLLAGASETLVEPAASEHEDMEQGETNDNFMGCSDEDEDEDEDDDDDDDDDEEMYETESEDSHIESDPGSKDNDINNILIGLYGSQYRYKEMRQIITPVGRKQLEPMLQSYRKVVGAELSERMVYEIN
What is the function of this protein?
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein.  This arginylation is required for degradation of the protein via the ubiquitin pathway.  Component of the N-end rule pathway with ATE2 and PRT6 (PubMed:19255443, PubMed:19620738, PubMed:22020282).  The N-end rule pathway regulates seed after-ripening, seedling sugar sensitivity, seedling lipid breakdown, and abscisic acid (ABA) sensitivity of germination (PubMed:19255443).  The end-rule pathway regulates various aspects of leaf and shoot development (PubMed:19620738).  Involved in the oxygen-dependent N-arginylation of RAP2-12, an activator of hypoxic gene expression.  This N-terminal modification leads to ubiquitination by PRT6 and subsequent degradation of RAP2-12 under aerobic conditions (PubMed:22020282).  Has an important role in the progression of leaf senescence (PubMed:12366806).  Involved in disease resistance (PubMed:27173012).  The end-rule pathway plays a role in regulating the timing and amplitude of the immune response following infection with the bacterial pathogen Pseudomonas syringae pv tomato (PubMed:27173012).  Regulates the biosynthesis of plant-defense metabolites such as glucosinolates, and the biosynthesis and response to the phytohormone jasmonate (JA), which plays a key role in plant immunity (PubMed:27173012).
What are the official names of this protein?
Arginyl-tRNA--protein transferase 1, Arginyltransferase 1, R-transferase 1, Arginine-tRNA--protein transferase 1, AtATE1, Protein DELAYED-LEAF-SENESCENCE 1.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family.
Protein: CP087_DANRE
Sequence: MSTNKVKKVKMATKSCPECDQQIPVACKSCPCGYVFISRKLLNAKLNERSGVMDKLEDKRRRTERIRKEKINLTSTSDMENRRRSRTNSHSDPIRRGRGRPKTVGLKKQEEEKEKQEREVDIYANLSDEKAFVFSVALAEINRKILGQRLIL
What are the official names of this protein?
UPF0547 protein C16orf87 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0547 family.
Protein: NPS6_ALTBR
Sequence: MSHHQAVSQLHLFVSILDALFSDPDCLLSSFMNVTEDELDELWSWNSPLQPELRFCMHEKVSEQAALHPEKIAIDAWDGTLTYRQVEDYSTDLAQTLQLLDGSHNQIIPVLFEKSRWTSVAVLAIMKAGACFALLDPAQPEGRLRAVVQQVSARLFVSSKAQATLAARVAPAATIIPVSASKFDKVYSPCAAQQPKTTLPPVSPDQPLYIQFTSGSTGLPKGCILTHSQYTSGAIPRADAVGYRSHSRVLDFASYAFDVCIDSMLCTLAHGATLCTPSDERRMNDMSGAMRDMRVTFAGMTPSVARTLDVDILDHLDSIALGGEGVSTSDAMSWGQRTRVVNAYGPSEATVGATINDNVASKPYITMGKRKGCAIWLTDPEDSNKLVPPGAVGELLIEGPIVATDISITRRKPRKFSLKIPNSWLKGSKSFPGRHGRIYKTGDLVRFDPDGNGEPIFVGRQDQQVKLRGQRIKLAEIEFNMQKHLPADTQLAVEVIKPSGGGEQTLVAFLVEQKKNGMRHLDGNVFGSFTTKFQSALKDMTKQLAVDLPGYMVPSAYIPLWKMPLLVSCKTDRKRLREIGTSVTRQDLRRFNSVISEKKEPTTEMEIKLRSLWGKLLGGEDDFSANDNFFSMGGDSLRAMRLVAAAREAGLVLNVPDIMLNPTLSAMATKIKPLSEEATNDVPAFSLIEKDWDMNSAKAETAKLCGVDVNEVQDVYPCTPLQEGLMALSAKFQDAYVAQRIATLPSETAQRLKEAFDTAAEGSPILRTRIVNVSGRGLFQVVLKNGRLLREHGADPAEYLRRDREEAMDLGTALFRYGLVQEAGSDETHFVITMHHAVYDGWSMPLIFDRINRAFNGLQTERSVSFKHFIKHLTSLDPAEAQDYWRERLAGVNPYQFPPLPQKGYTTQADSLLEHYVSVPTTAHNKLTLATIIRGAWALVSSLYMGHPDVVFGETLTGRSAPVNGIEEIEGPMITTVPIRVRLSLDRPISDYLQAVHAQTVKQIPHEHLGLQNIRRLSKDARVACDLRTGLVLHPREDDVGEVDMEAVPANTFLPADDAEAAREALKFNTYALMLVCTLDENGFLIMASFDSKCISKDAMERVLVVMNRIVTAFLGNPESKLGDVAVLDPSEAQDAEAMRPRDVMSDSGIGTSPIDSPKLDAAMKALSPNEEKLHSILGRILGMPETEIKSSDSFFELGGDSIGAMRLVSDARAQGLTLTVAQVFQSQSLAELAASIGNEKEDKLLDILSRILGMPKSEINGSDSFFELGGDSIGAMRLVSDARAQGLNLTVAQVFQSQSLSELASSAEETDSPQTETNSNAPYAALGKEASLYSPDRIGAYLQDQSWEIVDVYPTRPLQQLAVEGTVDLPRYSLRYELIKFATPINRQKLEQACQELVARNEVLRTVFVKDESKVLGVVLSSPRVPYSEIAVPDGEDINAFSQANIQKDIEAPKPHGSS
What is the function of this protein?
NRPS involved in extracellular coprogen-type siderophores biosynthesis (PubMed:17056706).  The role of extracellular siderophores in fungal virulence to plants is to supply iron to the fungus during plant infection, but not to act as phytotoxins, depriving their hosts of iron (PubMed:17056706).
What are the official names of this protein?
Nonribosomal peptide synthetase 6, NPRS 6, Extracellular siderophore synthetase.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: FUM2_ARATH
Sequence: MAALTMQFEGEKKNVSEVADVTLKQEDEQQERRSYSTPFREERDTFGPIQVPSDKLWGAQTQRSLQNFEIGGDRERMPEPIVRAFGVLKKCAAKVNMEYGLDPMIGEAIMEAAQEVAEGKLNDHFPLVVWQTGSGTQSNMNANEVIANRAAEILGHKRGEKIVHPNDHVNRSQSSNDTFPTVMHIAAATEITSRLIPSLKNLHSSLESKSFEFKDIVKIGRTHTQDATPLTLGQEFGGYATQVEYGLNRVACTLPRIYQLAQGGTAVGTGLNTKKGFDVKIAAAVAEETNLPFVTAENKFEALAAHDACVETSGSLNTIATSLMKIANDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEALTMVCAQVMGNHVAVTIGGSNGHFELNVFKPVIASALLHSIRLIADASASFEKNCVRGIEANRERISKLLHESLMLVTSLNPKIGYDNAAAVAKRAHKEGCTLKHAAMKLGVLTSEEFDTLVVPEKMIGPSD
What is the function of this protein?
Cytosolic fumarate hydratase that catalyzes the reversible stereospecific interconversion of fumarate to L-malate (PubMed:29688630).  Catalyzes the dehydration of L-malate to fumarate in the cytosol: required for the massive fumarate accumulation during the day in plants grown under high nitrogen (PubMed:20202172).  Also required for acclimation of photosynthesis to cold: acts by mediating accumulation of fumarate at low temperature, leading to reduce accumulation of phosphorylated sugars (PubMed:27440755).
What are the official names of this protein?
Fumarate hydratase 2, AtFUM2, Fumarase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TRMB_SHIBS
Sequence: MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPVMGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLNNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDLMFERVK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ADN3_SCHPO
Sequence: MADFMDIEPSSHSAKASQYESSAPASSSLGNSHPNESLDYYIYDYFVKHNFEEAAQAFLRESKIQIPKSSSSTAFSPSNNNAPSPFPPKNSSLASPSKISESISGDRLYNHMSSAPSPNKKEETNVVHANEDISLDKRQSFGSSSLPPSEVSINVPEGFLVEWFNIFWDVFSARVSRVNSTPIQLYDPSTQRQMARPMSNLQASQPVPSSTFSRSAVVPNPSLPLNPSVLQGQVMNNPTIPKGTPSTSIEGAKTSIPPSHAMQNPHNSFPASADRLQKNHPVQSSNFNPYTPAPSITVPPNYIPNTAMMGPSYSSFGDTDPRTYPAGMGPNPTAARNGFYPPTPAQIHQLKAQQQHLQRQSKQMSEPAPINMKSNKDQQLQYVDFRGVGSGADLQKQQWNKSTSAEGLQPNGLVMRNFGDVRHQKLPTSSPPSQHPPVGQIPSQYLPYQAGLKVPGNTPIPVKQVGGMPLQSPLPVSMKPSADDHSRATPTRSVEAPTLPSYAPRHPTQANGSRYMNPSTSRMTPQSPYMQNYYRPHAQMQDQNNMMSYMLSQQKAMEIAKSREMAIQRNTQTLSSGNQPPQQSGPNPNEFSMSMDPANMQQGNHALSDYHMQLMLLEEQNKKRLMMARQEQGTGSLSPQSYMNSRYSVDVGKEHMSMIPNQTAPMIQPNVPVSANSPAQANTPAADSTKSGTIQPTNRNGEGLSYSPHQQFSPSAPQAEKLSRSMSPFVSQQQQLNQPVSNKPDGLTQNKEVTGMPLNKEELTNPAFPQSRTSWMMPQSFDTSSLNAPGAKDSSSFSSLHAQPGKSGIATMGVADNTIRTTERSTFSEIMKDSPSAHASPGAKTSPNASRAPEPTGGTNSISQDTTQSLQMQSNSVNSSSMVDASKSKEKSGGDTSALDSNAKNEPTAAKPISKLEDDALFNDSAGNAFGFSSKTDSNVEMLNDFDFESFLNDAGADSASVYY
What is the function of this protein?
Probable transcriptional regulator involved in cell adhesion.
What are the official names of this protein?
Adhesion defective protein 3, LisH domain-containing protein adn3.
What is the protein family that this protein belongs to?
Belongs to the FLO8 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYL_CHLPM
Sequence: MRYDFSKTEKKWQARWKQQETFKTGEAPEKPKYYVLDMFPYPSGSGLHVGHLEGYTASDISARYRRSRGYNVLHPMGWDAFGLPAEQFAIKTGTHPSDTTQKNIANFKETLQAMGFSYDWSREINTTDPGYFQWTQWIFLKLHEMGLAYMSEVDVNWCVELRAVLANEEVEEKLADGLTVVRRPLRQWVLKITAYADRLLEDLDGLDWPENVKQMQRNWIGRSEGVEVDFELRCHRTMLRVYTTRPDTLFGATYLVISPEHAMAEKLATAQQLVAVKEYIAKAKLKTELERTGLQKDKTGVFTGSYAINPATGEPLPVWISDFVLTSYGTGAIMSVPAHDSRDWEFAKQYGLPIIEVVKSPHDVQQEVFEGKDSTVVNSSNNDISLNGLAFPEAFELMASWLEKKKAGKRKVNYRLRDWIFSRQRYWGEPIPIKHYPDGTLKPETSLPLMLPEVEAYQPTETGESPLANIPEWLNGTDENGPFRRETNTMPQWAGSCWYYLRFIDPHNSKLPVDPAKEAYWMNVDLYIGGAEHAVLHLLYARFWHKVLFDLKVVSTKEPFQRLFNQGMILGEDNEKMSKSRGNVIPADHVLQTYGADAVRLYEMFLGPLEQVKPWNTNGIEGISRFLSRVWRLVWPEPEGTRADLSTLAPSPDLLRRMHKTIKKVAADTENLKFNTAIAEMMVFTNELHRTGEGSRIAVETLLLLLAPYAPHLSEELWEALGHQESISLAPFPEFDPELAQDKEVTIAVQVNGKLRGSFTAAPGSPKEQLLNEAKALEGVKKFLEGVTIMKEIVVPDKLINFAVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNX_BACMK
Sequence: MSIQVFCDFDGTITNNDNIMSIMEKFAPPEAEEIKQKILSQELSIQEGVSQLFRLIPINLHDDIIQFLQETAEIRTGFHEFIQFINENNISFYVISGGMDFFVYPLLQEIIPKEQIYCNATDFSGEFVEVKWPHPCDEQCQHSCGLCKSSLIRKLSSKDDFHIVIGDSITDLQATKQADKVFARDFLITKCEENRIAYTPFETFHDVLAELKHLLEVKL
What is the function of this protein?
Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase, HK-MTPenyl-1-P phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MtnX family.
Protein: SCEL_MOUSE
Sequence: MSNFSSRKKSPTGNDLKSARGAELRQQGFQDVNKRRAFLQDNSWIKKPPEEEQDGNYGRVVLNRHNSHDALDRKLIERDEPKATISRYRSEDMLDRTLSSFRTPQSTKTPAVSSFNANTTATASTPATTPVKKKRQSWFPPPPPGHNASPSTAASRRDPALHPPLPPKPCSPIASPKPLGRTNRQIHAATAGACGETERHAERNIRTEDLDDIIRVAAALQKTDKGEELDNLIRMNKSLNRNQGLDGLFRANLKAQQLDKRAQSLESLIYMNTQTDRDGKGNQAFGSLKKINQRADPDRRSQDLRSVIRTHATAERIGRRKQDLDGLIKVNPDTNKNMKRGKSLDNLIKVTPEVNRSNKGGPSLDNFTKGVPARSRANQRDQDLDSLIKVTPSANRSSQHSLDELINTSPQTIKTTARHQDLDKFIKVNPDVLTNNQRNHDVDSTIRGNPTGTRCEQSEELDNLIKVKPSALRNTNGGQDLESLTEVNSHVAEKNGRIDGQANGLTNSLFKESTRASVYSYEARNSLSSNSGNKNGGPKDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKRPLENLQAGDSIWIYRQTIHCEPCYSKVMAKWIQ
What is the function of this protein?
May function in the assembly or regulation of proteins in the cornified envelope.  The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope (By similarity).
What are the official names of this protein?
Sciellin.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=May become cross-linked to membrane proteins by transglutaminase.
Protein: USPE_SHIFL
Sequence: MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDFSYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQEVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAVNLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYNDAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGISAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD
What is the function of this protein?
Required for resistance to DNA-damaging agents.
What are the official names of this protein?
Universal stress protein E.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIB2_RAT
Sequence: MDLDPHAGVQVGMRVVRGMDWKWGQQDGGEGGVGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGIRHPNIICDCCKKHGLRGMRWKCRVCFDYDLCTQCYMHNKHDLTHAFERYETSHSRPVTLSPRQGLPRIPLRGIFQGAKVVRGPDWEWGSQDGGEGKTGRVVDIRGWDVETGRSVASVTWADGTTNVYRVGHKGKVDLKCVGEAAGGFYYKEHLPKLGKPAELQRRVSADGQPFQRGDKVKCLLDTDVLRDMQEGHGGWNPRMAEFIGQMGTVHRITDRGDVRVQFNHETRWTFHPGALTKHNSFWVGDVVRVIDDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVGGQRWTFSPACLVACRPEEDANLGVAERARENKSAASVPVAGSLSVALDKLRTQKSDPEHPGRLVVEAALGNVARALDLLRRHPEQAGFHPAVDTKNQGRTALQVAAYLGQVELVRLLLQARASVDLLDEEGNTALHYTAMGNQPEATRLLLSAGCGVDAQNGTRSTALHVAVQRGFLEVVKILCEHGCDVNLPDAHADTPLHSAISAGAGASSIVEVLTEVPGIDVTATNSQGFTLLHHASLKGHVLAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQVLIREGRCDVNVRNRKLQSPLHLAVQQAHLGLVPLLVDAGCNVNTEDEEGDTALHVALQRHQLLPLVADRAGGDPGPLQLLSRLQASGLPGSTELTVGAAVACFLALEGADVSYANHRGRSPLDLATEGRVLKALQGCAQRFRERQAGGGGGVPPGPRHVLSTPNTVTNLHVSGTAGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVIISKKLRPDGSEVVNAIQVPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAPCGAALNACPICRQPIRDRIQIFV
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins.  Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
What are the official names of this protein?
E3 ubiquitin-protein ligase MIB2, Mind bomb homolog 2, RBSC-skeletrophin/dystrophin-like polypeptide, RING-type E3 ubiquitin transferase MIB2.
What are the subcellular locations of this protein?
Cytoplasm. Endosome. Note=Colocalizes with endosomal compartments.
Protein: RL11_KORCO
Sequence: MPKKIVRVLIEGGKATPGPPLGPALGGLGLNMGQIVKEINEKTSSYSGMRVPVEIEVDTETKKFEIRVGTPPTSMLILRELKAEKGSSDASKKIGNLKMETVVNIAKMKLASSNTPELKQVVKQVLGTALSMGVTVEGKDPREVQREVDSGAWDKLLGG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PUR5_HAEIN
Sequence: MSNTQLSYKDAGVDIHTGNELVERIKGDVKRTRRSEVMGGLGGFGALCALPTKYKEPILVSGTDGVGTKLRLAIDLKKHDTIGQDLVAMCVNDLIVQGAEPLFFLDYYATGKLDVDVAASVIKGIADGCEMSGCALVGGETAEMPGMYHEGDYDLAGFCVGVVEKSEIIDGTAVKTGDTLIALGSSGAHSNGYSLIRKVLEVSGANPTDLLEGKPLSEHLLAPTKIYVKSILQLIKQTEVHAIAHLTGGGFWENIPRVLPDNTKAVIDESSWQWPAIFNWLQEKGNISRYEMYRTFNCGVGMVIALPEKEVETALALLEQSGEKAWVIGKIEHLGESEAQVEIQ
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_LEGPH
Sequence: MSSLTGKLIVIEGLEGAGKSTAVNLVVELLSQKKISTITTREPGGTKIGEILRSIIKNPEYNNVLDDRSELLLLYAARIQLIEQVIKPALNVGQWVIADRFELSTLAYQGGGRKMDMRVINELSNFCLKGFKPDLTLYLDINPELGMIRAKSRGKFDRIEQESIEFFHRIHDTYHILVKQNPEIIMIDANRSLEEVQSSIQSVIEEFIEHNL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: THSD1_BOVIN
Sequence: MKQTLKDFSNLLLVVLCDYVLGEAEHLVLGEPGHVALSNSTVTVDFHGANGTLRNVSVLLVEASSNQTLTTKYLLTNQSQGTLEFECFYFKEAGDYWFVMTREATNSSLPVPPRERSAFLKVEWPVFHVDLSRTSMAAEGTFQVGLFTSQPLCPFPGDKPDILLEVTFTNSLPEARAGQALPLEIRASKRVELAQGQWVEFDCPPVGPEAYVTVTVVLKLLGRDSVIMSTGPIDLAQKFGYKLVMEPELTCEAGVEVTVLPPPCIFVQGVIAVFKEAPRLPGERTNRLAENSLALGERRTGFNCTLFDMGRNKYCFDFGVSSQSQFSAKEKECMLIRRSIETWGLWQPWSQCSASCGDGVRERRRVCLTSSPSRPGCPGMSSETSPCSLEDCAAFQPSSPSPLQPQAPVKSNNVVTVTGISLCLFIIVATVLITLWRKLGRAPKCSTPARHNSLHGPGCRKNSDEENICELSEPRGSFSDAGDGPAGSPGDPGIPLTYRRSVPAPPDDEASGSESFQANAQKIIPPLFSYRLAQQQLKEMKKKGLTETTKVYHVSQSPLTDTAIDAAATAAAAAAASPGGSESPEEAAAGKFRIKSPFLEHPPTVGAGDRPPSRLDHPFSAASCAVSPSQTLLRKSQVRSHSRGSHFRRTASFHEARQARPFRERSLSTLTPRPTPAHGPRARTWDQAGERGRPPSRGTALFPEKRDHGPGAAGASGPLSPLPKPHSLGPPPRKPDLGDRQAGFVGAGERPEPPRARRGPSPSHRSVSRKQPSPPAPKDGYQRVSPLSPSQGRKDKCQSFPAHPEFAFYDNTSFGLTEAEQRMLDLPGYFGSNEEDETTSTLSVEKLVI
What is the function of this protein?
Is a positive regulator of nascent focal adhesion assembly, involved in the modulation of endothelial cell attachment to the extracellular matrix.
What are the official names of this protein?
Thrombospondin type-1 domain-containing protein 1.
What are the subcellular locations of this protein?
Endosome membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Note=Localizes to nascent focal adhesions.
Protein: RDGC_YERPY
Sequence: MLWFKNLMVYRLSREVSLSADEMEKQLSAFSFTPCGSQDMAKTGWVSPMGSHSDALTHTVNGQIVICARKEEKILPSPVIKQELQDKIERLEGEQHRKLKKTEKDSLKDEVLHSLLPRAFSRFNQTFLWIDTVNDLIMVDAASAKRAEDTLALLRKSLGSLPVVPLTLENPIELTLTEWVRSKTLPAGFALMDEAELKAILEDGGVIRCKKQDLFSDEIAVHIEAGKLVTKLALDWQERIQLVLSDDGSLKRLKFADTLRDQNEDIDREDFAQRFDADFILMTSELAALIKNLIEALGGEAQH
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PHLG_PSEF5
Sequence: MEARNMTPFTYFSLPMQKLFLRNQAAVRNKPYAKYFRSEMRVPLSAVRKIQQGPMALEDTLTPSIEDINRLLEPDFVSEESGYALLPGPMAYVQSRKFFPGCTAQMFKWWFIWHPAESERYTLWFPYAHVSNPCVHHQRLRDESLSFEERLYGNTFCASEYVGDRLMHLHIDFQQPASLGLNTDLYREAKIDGSVSALMSLADHPEVPVSLMVHLFKEVPDGMYLTSRYWVGAHPSMARFPGAEKAASLLKENGFGEAELETLAYEFAVHDMCEFNHLASFLPDLYREFGTPAA
What is the function of this protein?
Hydrolase that specifically degrades the potent antimicrobial compound 2,4-diacetylphloroglucinol (DAPG) to equimolar amounts of mildly toxic monoacetylphloroglucinol (MAPG) and acetate.
What are the official names of this protein?
2,4-diacetylphloroglucinol hydrolase, DAPG hydrolase.
What is the protein family that this protein belongs to?
Belongs to the DAPG/phloretin hydrolase family.
Protein: ADAR_ASPNC
Sequence: MEQRSSPARSLPPRKTTTTPQLSCELCRKRKVKCDKLTPCTNCAASGTVCVPIYRTRLPRGRHATRPRRVSSPPPTSAPGETDRIIQPSVPVNEDLQERIYRLEALIQGMNSHSHTRTPSATSREQSVQLSDTSTFQTAPNPNTSPILNSSIVSKRLMLQRPDQFWADLVDEIHGLREVVESSLAGGQEGPIPSSDSAKSEPPNDDGIQVLGLGASNPSAALRSMSPLHNPVVARQLCEVYLQQVDPVIKILHRPSLNRWMVQGEPYLSYADGHPAVEALGSAVCYSAISSMTDNQCSVMFHANKADLLAEARVACETAIGRAGLLTTRDITVLQAFVLYLVARRSEDRTPAVWTLIALAVRIGKGLGLYLDPETETFFDQQIRRRLWFTICLMDLQASFGQASEPLISVDESASTALPQHINDSDFDPTTAAHSDPNREGLTDTTFALVTYHAQRTGRLLNFVQHDRKVDGGIPTPTSSTSGTSTSRSRTCDPSWPQQQARHFEQEALRLLHFCDPGTSAYAWFTWHGTQSLIATVRLAAARPLQWHGQAPPPRREGNTELLRLCLPVLEKAQLMHTDPRAEGFRWYVTIPWYALAMALAECYVSSDTALVRYAWPLVESSYLQYEATLGQSLGGPFGQLMRRMKEKLAAPAALPPSSLPSTNWSPATPPTFPGVPRPQSSHDDRHAPGCSWPVPTGSTPPADLGVPSLLPVSTWEALSPPSLDNPSLFGVPPTTTAVADGMDPGADIMWEELFSGIPFNEIAGPDTFFFDMNWGS
What is the function of this protein?
Transcription factor that specifically regulates the expression of the ada gene cluster involved in the biosynthesis of the linear tetracyclic TAN-1612 neuropeptide Y receptor antagonist.
What are the official names of this protein?
C6 finger domain transcription factor adaR, 2-acetyl-2-decarboxamidoanthrotainin biosynthesis cluster protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_YEAST
Sequence: MAFQKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDIICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYKGVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRFPGWDFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIYTSAHEAIRADPAFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L5, L1, L1a, Large ribosomal subunit protein uL18, Ribosomal 5S RNA-binding protein, YL3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The SYO1-uL5-uL18 complex is transported into the nucleus by KAP104.