PharMolix/UniProtQA huggingface dataset:
Protein: ATPF_SACD2
Sequence: MNINLTLIGQSLTFIAFILFCMKYVWPQLIAMMEEREKRIAEGLEAADRADKDLELAQKKAGKQLTEAKEQAATIVEQANKRGNQIVEEAKEAAVAEGERIKAAAQAEIERQVAQAREELRGKVAALAIQGAEKVLGTTVDAKAHSEMLDKLAAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ZN335_MOUSE
Sequence: MEENEVESSSDAAPRPGQPEEPSESGLGVCTSEAVSADSSDAATVPGLTEADDSGVGQSSDGGNHSVEEVSESISTDPLPHGCLPDSSSVSRGPVAEMPGGPPALVHSSVLPDPSMLVSDCTASSSDLGSAIDKIIESTIGPDLIQSCITVTSGEEGGAETTQYLILQGPDDGAPMASSMSTSTLANSLAAIEALADGPTSTSACLEPPEEPQGDPSSVAQQPPAPVTEELDLQSLEAMMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRPALAAAAAATGKRGRVRKWGTSTKTTEEDRPEEEEEDDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLETSDLHDGVGQPLVSSQSTQSPPELQDLEAPSSSGLRALGKVGRGLVESGVSQSDAENAAPSCQDEADAPPRRRGRPSRRFLGKKYRKYYYKSPKPLLRPYLCRICGSRFLSHEDLRFHVNSHEAGDPQLFRCLQCSYRSRRWSSLKEHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSQDRKKRPDPTPKLSSFPCPVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVANRRFKCEFCEFVCEDKKALLNHQLSHVSDKPFKCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLRLHVRCRHANSFEEWGRRHPEEPPSRRRPFFSLQQIEELKQQHSTAPGPPLSSPGPEAPQEPAPFQSPETPPLLCPDALGGTTIIYQQGAEESTAVATQTALDLLLNMSAQRELGATALQVAVVKSEGIEAELTSTGGQPSPEDTTPRVVTLHMAESGSSVAAESQLGPSDLQQIALPSGPFGGASYSVITAPPVEGRTSASGPPYREEPPGEAAQAVVVSDTLKEAGTHYIMAADGTQLHHIELTADGSISFPSPDTLAPGTKWPLLQCGGPPRDGSEVLSPTKTHHMGGSQGSSTPPPAASHTLGLVVPQSPPSAAASSTKKFSCKVCSEAFPSRAEMESHKRAHAGPAAFKCPDCPFSARQWPEVRAHMAQHSSLRPHQCNQCSFASKNKKDLRRHMLTHTNEKPFSCHVCGQRFNRNGHLKFHIQRLHSIDGRKTGTSTARAPAQTIILNSEEETLATLHTAFQSSHGVLGTERLQQALSQEHIIVAQEQTVTNQEEATYIQEITADGQTVQHLVTSDNQVQYIISQDGVQHLLPQEYVVVPDGHHIQVQEGQITHIQYEQGTPFLQESQIQYVPVSPSQQLVTQAQLEAAAHSAVTAVADAAMAQAQGLFGTEEAVPEQIHQLQHQGIEYDVITLSDD
What is the function of this protein?
Component or associated component of some histone methyltransferase complexes may regulate transcription through recruitment of those complexes on gene promoters (By similarity).  Enhances ligand-dependent transcriptional activation by nuclear hormone receptors (By similarity).  Plays an important role in neural progenitor cell proliferation and self-renewal through the regulation of specific genes involved brain development, including REST (PubMed:23178126).  Also controls the expression of genes involved in somatic development and regulates, for instance, lymphoblast proliferation (By similarity).
What are the official names of this protein?
Zinc finger protein 335, NRC-interacting factor 1, NIF-1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TIG_THENN
Sequence: MEVKELERDKNRVVLEYVFNREEVLEAEDKAARYLNQRVEIPGFRKGRVPKNILKMRLGEDFQEYTLDFLMDLIPDTLKDRNLIMSPVVTEREIKEDTARFVVEVHEEPEVKIGDVSKIEVEKVDEEKVLEKYVERRLEDLREKHALLEPKEGPAEVGDLVRISMEVYNEEGKNLTTREYEYVIKEGEDRPFVKDLIGKKKDDVVEIEREYEGKKYTYRLKVQEVYRRTLPEIGDELARTVNNEFETLEQLKEELKKEGKDIYDVEMKESMREQLLEKLPEVVEIEISERTLDLLVQETINRLKREGRYDQIVSSYESEEKLKEELKKRILDDIKRDRAIEVIAKERNVDVSDEELEKEAEELAPFWGISPERAKSLVKSRRDLREDLRWAILKRKVLDLLLEEVTVKVVEPRGEGDGDERKGDN
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: IAP_ASFWA
Sequence: MFPKINTIDPYISLRLFEVKPKYVGYSSVDARNQSFAIHDIKNYEKFSNAGLFYTSPTEITCYCCGMKFCNWLYEKHPLQVHGFWSRNCGFMRATLGIIGLKKMIDSYNDYYNNEVFVKHKNRVYTHKKLEDMGFSKPFMQFILANAFIPPYRKYIHKIILNDRYFTFKFAAHLLSFHKVNLDNQTTYCMTCGIEPIKKDENFCNACKTLNYKHYKTLNFSVKL
What is the function of this protein?
Prevent apoptosis of host cell by inhibiting caspase-3/CASP3 activation to promote the viral replication.  Induces also the activation of host NF-kappaB.
What are the official names of this protein?
Inhibitor of apoptosis protein, IAP.
What is the protein family that this protein belongs to?
Belongs to the asfivirus IAP family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Probably accumulates in the perinuclear cytoplasmic viral factories. Found in association with viral nucleoid.
Protein: MED30_ARATH
Sequence: MLQKQVSTTTTMTTQELAMEGEKQLEETIEAAFQIISAMNDELCNPSLWSTSATPSSAATTTGSNGSALVSADAAAIDGTSHHSESAGGGGGGGSGNSVLDEASLRYKNSVTSLRAVLAAIPNSQKAKASEMQNGLGSPESEDEIEKLEEQALSLRMEIAKKNVHVKELIDKLRELIADISTWQSPCSV
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 30.
What is the protein family that this protein belongs to?
Belongs to the plant Mediator complex subunit 30 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOB_VEREI
Sequence: MAYSFTERKRIRKSFGTRDSVLEVPYLLQMQKDAYTAFLQADKEPRKRTIEGLQAAFDAAFPIVSHNGFVEMKFIEYNLARPAFDVRECQTRGLTFASAVRAKVQLIIYDRESSTSQSKVVKEVKEQEVYMGEVPLMTDKGSFIINGTERVIVSQLHRSPGVFFEHDKGKTHGSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKAIGLNPESILANFFVNDNFRLMDSGAQMEFVPERLRGEVARFDITDKSGKLIVAKDKRVTARHTRDLEQSGSTHISVPEDFLVGRVVARTIVDADSGEILAKANDELTEALLKKLRSAAVRELQCIYTNELDQGAYISHTLRSDETVDEFAARVAIYRMMRPGEPPTEDAVQALFQRLFYNPDTYDLSRVGRMKFNARIGRDESTGPMVLSNEDILAVVKILVDLRNGNGEVDDIDHLGNRRVRCVGELAENQYRTGLARIEKAVKERLGQAEQEPLMPHDLINSKPISAALKEFFGASQLSQFMDQTNPLAEITHKRRVSALGPGGLTRERAGFEVRDVHVTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFIETPYRRVVGGMVTNDIDYLSAIEEGKYVIAQANAVLDKEGRLTGDLVSAREKGESILCAADRVRYMDVSPAQIVSVAASLVPFLEHDDANRALMGANMSRQAVPVLRPEKPLVGTGIERVAAIDSGTVVTATRGGSVDYVDATRIVVRVNDDETVAGEVGVDIYNLIKYQRSNQNTNIHQRPIVKKGDRLVKGDVIADGASTDLGEIAIGQNMLIAFMPWNGYNFEDSILISERVVSEDRYTSIHIEELVVMARDTKLGAEEITRDIPNLSEQQLNRLDESGIIYVGAEVQPGDTLVGKVTPKGETTLTPEEKLLRAIFGEKASDVKDTSLRVEQGSQGTVIDVQVFTREGIARDKRAQQIIDDELKRFRLDLNDQLRIVEADAFERIEKLLLGRVANGGPHKLLKGAKIDKPYLSSVEKFHWFDIRPAQDEVAAQLELIKDALEQTRHSFDLAFEEKKKKLTQGDELPAGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPYMADGTPADIVLNPLGVPSRMNIGQVLEVHLGWASKGIGQRIGDMLQQQAKAAELRKFLDKVYNARGRTEDLAQLCDEELVAMAAHLRHGMPYATPVFDGASEEEIKDMLKIAYPDEIAQRKGLTATRTQAFLYDGRTGERFERPTTIGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYVLQEMLTVKSDDVAGRTKVYESIVKGEHAIEAGMPESFNVLVKEIRSLGLDIELERS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ATPA_RHOE4
Sequence: MAELTISSDEIRSAIDNYTASYSPEASREEVGTVTDTSDGIAHVSGLPSAMSNELLEFPGGIVGVALNLDATEIGAVILGDYQNIQEGQEVKRTGDVLSVPVGDAFLGRVIDPLGAPIDGLGEIESTENRALELQAASVLERQPVEEPLQTGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCIDAILNQKANWDSGDVNKQVRCIYVAIGQKGSTIAGVKAALEEKGAMEYTTIVAAPASDSAGFKWLAPYTGSAIGQHWMYQGKHVLVVFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERSAKLSDALGGGSLTALPIIETKANDVSAYIPTNVISITDGQVFLESDLFNKGVRPAINVGISVSRVGGAAQTKGMKKVSGSLRLELAQFRELEAFSAFASDLDAASKAQLERGARLVELLKQDQYSPIPVEDQIVSIYLAGEGIFDSVPIGDVRRFEKELLEDLKHSAAGVYSSINGGKALDADNAAALIAATNKFKEGFIASDGSRVVNEAEADALGADEVENEQINVKRKTVSK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MTFA_SHISS
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTGLTEQEQSKLVTLAERFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGLA_SHIBS
Sequence: MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLRRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKQINNHNANEAINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDKSRMKSDTQWVIDSMRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQNEILRLASLHL
What is the function of this protein?
Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Galactose/methyl galactoside import ATP-binding protein MglA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: H2B11_ARATH
Sequence: MAPKAEKKPAEKKPASEKPVEEKSKAEKAPAEKKPKAGKKLPKEAGAGGDKKKKMKKKSVETYKIYIFKVLKQVHPDIGISSKAMGIMNSFINDIFEKLAQEASKLARYNKKPTITSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.11, HTB4.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PELO_DESA1
Sequence: MRVLEEDLRNGYIRILVEDIDDLWILFMVLRKGDIVYARTSREVKPGEGGSSRRIPMVLGLRVEAIEFQEFTEKLRIRGIVVEGPEEFGVKGHYHTIAIGVGDQLAIVRETWSKHSLDILKKGVRRRRILLVSIDYDSACIAVLTEQGVKHHSEIQSDLPGKMYRVEHEEILDEYLSKVASALNNVIQQEEIDAVIIAGPGDLKNKLGENIRRDNRKHVYLDTTSTGGCQGISELLGRDVVKQVVGDLSIVKAKEVVEEFKRLIIKDPQLVAYGVDDVYGAVVYAAVSRIVVAGDLLHEPDDERRARVYEILEKAYETGAEVIIVPGKSDVGLEVQGFGGVIAVLRYRLFRGEHSP
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMA_ROSDO
Sequence: MTVSVDDLCVTRGGVPILSGVSFDLAEGAALILQGPNGSGKTTLLRTLAGLQPPLAGQISGTEDRIAYAAHSDGLKSMLSVAENLRFWAAVFGRSDIAPALQAFDLHDLADRLAGTLSAGQKRRLGLARLLVTGRPVWMLDEPTVSLDKRAVEMFAAAVEAHLATGGSALIATHIDLGLRDAQVLDVGPLRASPTALAGASDEAFL
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL9_SALAR
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNVEYFEARRAELEAKLADVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVDVAKSEVRLPNGVLRTTGEHEVNFQVHSEVFAKVIINVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PGK_NEIG2
Sequence: MAFLKLTEQNVRGKTVLIRADMNVPFKGGKISDDTRIRASLASVKYCLDNGASVIVMTHLGRPTEGEFHPEDDVAPVAAHLGGLLGKDVKVLNDWRENKPALNAGDVVMLQNVRINKGEKKNDLELGKAYAALCDVFVNDAFGTAHRAQASTEAVAQAAPVACAGVLMAGELDALGKALKQPARPMVAIVAGSKVSTKLTILESLADKVDQLIVGGGIANTFLLAEGKAIGKSLAEHDLVEESKKIMAKMAAKGGSVPLPTDVVVAKAFAADAEAVVKDIADVAEDEMILDIGPKSAAALAELLKAAGTVVWNGPVGVFEFDQFAGGTKALAEAIAQSKAFSIAGGGDTLAAIAKFGVTEQIGYISTGGGAFLEFLEGKELPAVAALEKTRRVNGLI
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDFR_ECO5E
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNTLIRDLLKINVLDEVY
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: TRPC_ALKMQ
Sequence: MILDKIIRYKKNKVKEEKVAVPLGEIMKQIEDMEEARNFKAALVGRESISMIAEVKKASPSKGIIKKDFNPVKIAAEYEKNRVDAISVLTEDQFFLGDNRYLQDIRKMTTIPLLRKDFMIDAYQIYQSKALGADAILLIAAALTKKEMIAFQKIAAEIGIYSLVEVHNKEELEMILETGAEIIGINNRDLKTFDTTLDRTAELLPFIPKDKIVVSESGIKTNQDMKLLKNYGINAVLMGEGLMRADSIGEKLRELRSGLCD
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: NDB4U_LYCMC
Sequence: MKVNVLLAVFLVVMVVTDHCHALFGLIPSMMGGLVSAFKGRRKLQMEARFQPQNKNYRKRELDLENLFTHMPDY
What is the function of this protein?
Cationic host defense peptide that have antibacterial activity by breaking membranes.  Is more effective on Gram-positive than on Gram-negative bacteria.
What are the official names of this protein?
Antimicrobial peptide 36.4.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: Y1649_LISIN
Sequence: MAKMTTLKMKERLEKELNKPNRQFAYERDSDTLSVTQNGKKVTLAIPQIIANYENDGEAAIEKIIYYVEEGFLAASGNIELKNNTANIYPVVRATSFPDTTKAGEVLLTDEHTAETKIFYAFDLGKSYRFIEKNMLEKEGLSHEEVRKAAFDNLGKLEIPLKKDSVNGNDFYFVRTNDGYDASRLLNVSFLQQMREKLTGEMVLAVPHQDVLIIGAIKDNTGYDVLAHMTMDFFADGLVPITSLPFVYNNGKLEPIFIMAKNRLKE
What are the official names of this protein?
UPF0354 protein lin1649.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.
Protein: MNMG_CUPNH
Sequence: MLYPKEFDVIVVGGGHAGTEAALAAARMGCQTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDAMGGAMAAATDESGIQFRILNSSKGPAVRATRAQADRVLYRKAIRTRLENQPNLMLFQQAVDDLMVEGDRVVGAMTQVGIAFRARAVVLTAGTFLDGKIHVGLDNYTGGRAGDPAAVSLSARLKDLKLPQGRLKTGTPPRIDGRTIDFSVMEEQPGDLDPVPVFSFLGRPEQHPQQLPCWITHTNSRTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFATKESHQIFLEPEGLTTNEFYPNGISTSLPFDVQLELVHSIRGMENAHILRPGYAIEYDYFDPRGLKASLESKAISGLFFAGQINGTTGYEEAAAQGLLAGINAGCYVRERDAWTPRRDQAYLGVLVDDLITRGVTEPYRMFTSRAEFRLSLREDNADMRLTEVGRELGVVDDARWDAFNRKRDAVSRETERLKSTWVNPAMLPGEDAVPLLGKPIEREYSLADLLRRPEVRYEALMALQGGRHAPETPLDAEPMLAEQIREQIEIGIKYHGYIARQAAEVDKLEANESTRLPEGLDYTEVRGLGFEVSQKLNQHRPETLGQASRISGVTPAAISLLLVHLKKKGLGRTRAESGAPSGNSEEAA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_DEHMC
Sequence: MSRETGAVCRMCRRSGDKLFLKGDKCVTKCVFEKRPKPPGPQLGRPRRLSDRGQQLRQKQSIRWSYGMTERQFRRFFGLANAQPGVTGDNMMILLERRLDNVLFRLGFGTSRAQARQIVMHGHILVNGQKTDIPSYLIKEGQEITVRETSKATAYFKTLAENIEAKAIPGWLSLDRKTLSGKVISLPNAGDIDARFDAQTVVEYYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TGT_LEPIN
Sequence: MIFQTTSEDTLTKARTGILNLNGIELKTPVFMPVGTRGVVKTLSADDLEELEYSLILGNTYHLYLRPGTSVLDRFGGLKKFSTWKKALLTDSGGYQVFSLNSLFKYEQDGVRFQSHIDGSRHYFTPNSVIDIQRSIGSDIMMVLDDCAPFDSGPERLKQSLDRTHRWAEMSVQYWEKNKNSQHLFGIFQGGIDLDFRLESLNTITSLPFDGIAIGGLSVGEPRKDFIRILDGISAHTDRNRPLYLMGVGTVPDILDGVKNGVDMFDCVLPTRNARNGQVFTTLGKINLRNEKWKSSDTPMDPNCTCKVCKRYSIGYIRHLHHVGEITAFSLSTYHNLHFMKNFLTEIQNSIQKGEFLEIYAKWKNLYEKPEFSG
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: EXE1_HELSU
Sequence: HSDATFTAEYSKLLAKLALQKYLESILGSSTSPRPPSS
What is the function of this protein?
O-linked and free exendin-1 and exendin-1b have vasoactive intestinal peptide(VIP)/secretin-like biological activities.  They interact with rat and human VIP receptors 1 (VIPR1) and 2 (VIPR2), with the highest affinity for the human VIPR2.  They induce hypotension that is mediated by relaxation of cardiac smooth muscle.
What are the official names of this protein?
Exendin-1, Helospectin I, Helospectin-1, VIP-like 1.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: FXF1A_XENLA
Sequence: MTAEIQQPPSQPPAQSSPMSAATDKHGGQPSAMESASCATKTKKTNAGIRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHIPESYSFQGASGTISCPPNSLSLDSGIGMMNGHLPSNVDGMGLSGHPVSHLAANGAHSYMGSCTGSSGGDYSHHDSGSPLLGGGGVMEPHSVYSSPASAWAPSASTPYIKQQPLSPCNTAANPLSSSLSSHSLDQSYLHQNSHNTASELQGIPRYHSQSPSMNDRKEFVFSFNAMASSSMHSGSGSYYHQQVGYQDIKPCVM
What is the function of this protein?
Probable transcription factor.  Required for smooth muscle (visceral mesoderm) differentiation during gut development.  Also required for normal proliferation of the lateral plate mesoderm.  Acts as a downstream mediator of bmp4-signaling (By similarity).
What are the official names of this protein?
Forkhead box protein F1-A, FoxF1-A, FoxF1a, Fork head domain-related protein 13, xFD-13.
What are the subcellular locations of this protein?
Nucleus.
Protein: EUTC_SALPC
Sequence: MDQKQIEEIVRSVMASMGQDVPQPAAPSTQEGAKPQCAAPTVTESCALDLGSAEAKAWIGVENPHRADVLTELRRSTAARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLSPEAIDALKSQCVMNPDVQVVVSDGLSTDAITANYEEILPPLLAGLKQAGLNVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRVATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: HOSA_SULIM
Sequence: MIKVGILDSTLREGEQTPGVIFTVDQRVEIAKALSDLGVSMIEAGHPAVSPDIYEGIKRIVKLKKEGIITSEIVGHSRAVKRDIEIAAELEVDRIAIFYGVSDLHLKAKHKATREEALRTIAETISYAKNHGVKVRFTAEDGSRTDFDFLVTVSKTARDAGADRVSIADTVGILYPSKTKELFSALTREVPNLEFDIHAHNDLGLAVANALAAIEGGATIIHATVNGLGERVGIVPLQQIAAAIKYHFGIEVVKLDKLQYVSSLVEKYSGIPMPPNYPITGDYAFLHKAGVHVAGVLNDPRTYEFMPPETFGRTRDYTIDKYTGKHALRDKYEKLGVKISDAEMDQILAKIKSNTTIRFYRDVDLLELAEEVTGRVLKPRPPEQIEALISVKCDSNVYTTSVTRRLSVINGVKEVMEISGDYDILVKVQAKDSNELNQIIESIRATKGVRSTLTSLVLKKM
What is the function of this protein?
Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate.  Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.
What are the official names of this protein?
Homocitrate synthase, HCS.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.