PharMolix/UniProtQA huggingface dataset:
Protein: SSUB_ECOLI
Sequence: MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVGRSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVGLGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRLEMQDLIVSLWQEHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVDIPRPRRLGSVRLAELEAEVLQRVMQRGESETRLRKQG
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TTM2_CAEEL
Sequence: MLDKIRFTVLLDRPFYQPGQTIQGHVVCEPHHPLEIDCVEGRLHGEIQYFQQLPPNHNRNGSPLPPSKTRVLIDEKAQLWKYQTVSEMLGLDVFYDENQNRHFSSESASASSSSLFTTAATFPIQIELPHFAPPSFYCPGSPVSIRFTLEIQLYNQGFKIASHEENLVVLNYESIKRQVTPKPVNFQKTFNFPKERSISLEMLLPTDVFTTTARLENCITICNRWKQSLKYVHLNIVRRISALNQNNEVIDTVKIDTTGVGLPSKTKIAVGETYSFRPTFNVPALPPNIHVNGLFKTEYSLKVTIGRAHNFVLASYEVPITIVTMDQSSRRSMQKEDILVDISASNNTLNNLPVDLLA
What is the function of this protein?
Involved in resistance to B. thuringiensis pore-forming toxin Cry5B downstream of the sek-1 and pmk-1 MAPK kinase pathway.
What are the official names of this protein?
Protein ttm-2, Toxin-regulated target of MAPK 2.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
Protein: PPOM_TOBAC
Sequence: MAPSAGEDKHSSAKRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIWDEGANTMTESEGDVTFLIDSLGLREKQQFPLSQNKRYIARNGTPVLLPSNPIDLIKSNFLSTGSKLQMLLEPILWKNKKLSQVSDSHESVSGFFQRHFGKEVVDYLIDPFVAGTCGGDPDSLSMHHSFPELWNLEKRFGSVILGAIRSKLSPKNEKKQGPPKTSANKKRQRGSFSFLGGMQTLTDAICKDLREDELRLNSRVLELSCSCTEDSAIDSWSIISASPHKRQSEEESFDAVIMTAPLCDVKSMKIAKRGNPFLLNFIPEVDYVPLSVVITTFKRENVKYPLEGFGVLVPSKEQQHGLKTLGTLFSSMMFPDRAPNNVYLYTTFVGGSRNRELAKASRTELKEIVTSDLKQLLGAEGEPTYVNHLYWSKAFPLYGHNYDSVLDAIDKMEKNLPGLFYAGNHRGGLSVGKALSSGCNAADLVISYLESVSTDSKRHC
What is the function of this protein?
Provides precursor for the mitochondrial and plastidic heme synthesis and the predominant chlorophyll synthesis in plastids.
What are the official names of this protein?
Protoporphyrinogen oxidase, mitochondrial, PX-2, Protoporphyrinogen IX oxidase isozyme II, PPO II, PPX II.
What is the protein family that this protein belongs to?
Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TTCA_BURL3
Sequence: MNAPHMNDTTADAATLDATAAPAGRPALTRREQKDAYENNKLFKRIVRQVGQAIGDFNMIEQGDKVMVCLSGGKDSYAMLDVLLRLRERAPIDFDIVAVNLDQKQPGFPEHVLPEYLKQVGVPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVAGELGATKIALGHHRDDIVQTLLLNMFYGGKLKGMPPKLQSDDGKNIVIRPLAYVKETDLEKYAELREFPIIPCNLCGSQPNLKRAEMKALIREWDKRFPGRVENMFNALAKVVPSHLMDTTLYPFQSLRASGVADPQGDIAFDEEPCASGDDTAAPGGAQPISIVQFDDL
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_PSEA7
Sequence: MEKREELYRGKAKSVYRTDDADRLILLFRNDTSAFDGKRIEQLDRKGAVNNKFNAFIMQKLEAAGIPTQFDTLLSDTECLVKKLDMIPVECVVRNFAAGSLVRRLGVEEGIALTPPTFELFLKNDALGDPFINESHVQAFGWATPEQLAQMKTYSFKVNEVLNKLFEEAGLLLVDFKLEFGLFHGQIVLGDEFSPDGCRLWDKETRKKMDKDRFRQGLGEVIEAYEEVARRLGVPL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SMS2_CARAU
Sequence: MRLCELHCYLALLGLSLVLCGRCANSQLEPDLDFRHHRLLQRASATGQATQDFTKRDVEKLLSLLSIPEMEMREKGLSMAGESEDLRLEQERSAESSNQLPTRVRKEGCKNFYWKGFTSC
What is the function of this protein?
Somatostatin inhibits the release of somatotropin.
What are the official names of this protein?
Somatostatin-2, Somatostatin II.
What is the protein family that this protein belongs to?
Belongs to the somatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: COX2_TAMCA
Sequence: MAYPFELGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINDPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTSDLSPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATLTSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKHFENWSSSML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GBPA_PHOPR
Sequence: MIMIITKKTLLPVTLALFSSGVMAHGYVSSVEGGVAESRAALCKFPANGTGEKNTNCGSVQWEPQSVEGPDGFPETGPPDGKIASAGLSQFSPLDEQTVDRWVKRPMQAGIQNFEWTFTANHITRNWRYYITKQDWNPNKSLTRSAFDLTPFCQISGDMAKPPMRVHHSCNVPERKDYQVILAVWEVGDTAASFYNVIDVMFDGDLPTVPDWAVGGQIYPSMDLKSGDSVYTRVFDASGENSALSTELTIETEQQGQANNWSYSLAQQINNVYDNIRAGKADGEGNFAPIYGANPIYLKEGSGLERVEIGYNIITPEPDHDLDISGLENEYQIGDEPVSLELNLTAQGDQFVELTVYNHNKEALANKQVTLNDGDSQAVSMRLSKSEPGHHMLVTRIKDSSEGSLIDQITNDFHLTEGGDPPEGDYDYIFPEGLKSYTAGSKVLATDGRIYECKPFPYSGYCIQWSPSATQFEPGVGSDWSTAWIKLN
What is the function of this protein?
Probably interacts with GlcNAc residues.  May promote attachment to both epithelial cell surfaces and chitin.
What are the official names of this protein?
GlcNAc-binding protein A.
What is the protein family that this protein belongs to?
Belongs to the GbpA family.
What are the subcellular locations of this protein?
Secreted.
Protein: BGL03_ORYSJ
Sequence: MAAAAAFFCALLFISVQHGVLGGYTRNDFPADFVFGAATSAYQYEGAAAEDGRGASIWDTFTHAGKMKDKSTGDVASDGYHKYKGDVKLMTETGLEAYRFSISWSRLIPSGRGAVNQQGLKYYNNIIDELTKRGIQVHVMLYHLDLPQALEDEYAGWLSPRIVEDFTAYADVCFREFGDRVSHWTILAEPNVAALGGYDTGEFAPGRCSDPFGVTKCTVGNSSVEPYVAAHNMILTHAAVVRLYREKYQTLQKGIVGINVLSLWSYPLTDSTADLQAAQRYKDFTYGWILHPLVFGDYPQVMKKAIGSRLPSFSKVQTELVKGTLDFIGVNHYFSLYVSDLPLAKGVRDFIADRSVSCRGLLQGVRFIAQTMQAPTRSMGDPHGLQLMLQHLKESYGDLPIYVQENGKYRKASSNDSLDDTDRVDYIKGYIEGVLNATRNGVNARGYFAWFFVDMFELLSGYQTRYGLYRVDFDDAALPRRAKRSARWYRDFLKSKRQPLQIAQQ
What are the official names of this protein?
Beta-glucosidase 3, Os1bglu3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: RL36_NOVAD
Sequence: MKIRNSLKSLKDRHRDNRVIRRRGRVYVINKTQKRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SYL_CHLPB
Sequence: MRYDFQSIEKKWQAYWNEHQTFLTKETVDKPKYYVLDMFPYPSGSGLHVGHLEGYTATDIISRYKRSRGHNVLHPMGWDAFGLPAEQFAIKTGTHPKVITEKNVSSFKDTLMRMGFSYDWNREINTTDPGYYAWTQWIFLQLLDRGLAYTSEIDVNWCEELKTVLANEEVAEKVADGHAVVRKPLRQWVLKITAYAERLLSDLDLVDWPESVKQMQRNWIGRSEGVEIDFQLPCHRTSLKVYTTRPDTLFGATYLVISPEHPMAEKLATAEHLIEAKNYIEEAKRKTELERTGLQKEKTGVFTGSFAVNPANGQALPVWISDFVLTSYGTGAIMSVPAHDGRDWEFAKKFDLPIVEVIKSPHDVEEAVFEEKGSVCINSSNDDISLDGLPFETSFGVMADWLEKKGTGKRTVKYKLRDWIFSRQRYWGEPIPVKYYEDGTLRPESDLPLTLPDIEAYEPTTTGESPLANISEWLYGTDENGSFRRETNTMPQWAGSCWYYLRFIDPGNTEKPVDPKKEQYWMNVDLYVGGAEHAVLHLLYARFWHKVLFDLGVVSTKEPFQKLFNQGMILGEDNEKMSKSRGNVIPADQVLGSYGADAVRLYEMFLGPLEQVKPWNTNGIEGVSRFLSRVWRLIYPEPGSMAELNEAPLTEDLTRTMHKAVKKITDHTEQLKFNTAISEMMVFVNELHKSGSRNRTAVETLLLLLSPYAPHICEELWEAIGHDTSITEENWPLFDPALAADNEVTIAVQVNGKLRGTVTAPAGSPKNILLDSARKEESVRKFLDGMSIIKEVVVPDRLVNFVVKPG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FK163_ARATH
Sequence: MAASSPSLLLPLGSASRNGLTTKNPNSSRYIAARVIASETREQSCKISNLSSRREAMLLVLGVSGGLSMSSLAAYAAGLPPEDKPRLCEAECEKELENVPMVTTESGLQYKDIKVGRGPSPPVGFQVAANYVAMVPSGQIFDSSLEKGLPYLFRVGSGQVIKGLDEGILSMKAGGKRRLYIPGPLAFPKGLVSAPGRPRVAPNSPVIFDVSLEFIPGLDSEEE
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP16-3, chloroplastic, PPIase FKBP16-3, FK506-binding protein 16-3, AtFKBP16-3, Immunophilin FKBP16-3, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: LEUD_POLSJ
Sequence: MQKFTVHKGLVAPMDRENVDTDAIIPKQFLKSIRKTGFGPNLFDAWRYLDAGFPGQDPASRKPNPDFVLNQPRYAGASILLARKNFGCGSSREHAPWALDQYGFRAIIAPSYADIFFNNSFKNGLLPIVLPEAQIAQLFDEVNAFPGYTLTIDLERQVIVKPQGKELPFEVQAFRKYCLLNGFDDIGLTLRQSDKIKAFEAERLAKKPWLNHTIPG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: UPP_STAES
Sequence: MSKVHVFDHPLIQHKLSYIRDARTGTKEFRELVDEVGMLMAYEVTRDLELQDVEIQTPVTKMTAKRLAGKKLAIVPILRAGLGMTDGVLSLVPAARVGHIGLYRDPETLEAVEYFAKMPQDIDERQIIVVDPMLATGASAIEAISSLKKRGAKSIRFMCLIAAPEGVEKMQEAHPDVDIYIAALDEKLNDKAYITPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: APAH_SALAR
Sequence: MATYLIGDVHGCYDELIALLQQVEFTPETDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLDGKGTPDGIYALDTGCCWGGKLTCLRWEDKQYFVQPSNRQMDMGEGEAINA
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: TRPB_SULSY
Sequence: MKYTYPNEKGYFGVFGGKYLPETLMPALEELEQQYLKIKNDGDFKRQLLYYLTEYAGRPTPLYFASRLTDVVGGAKIYLKREDLLHTGAHKINNTLGQVLLTKKIGKKRIIAETGAGQHGVSTATAASLFGLECTIYMGEEDAERQALNVFRMKLLGAEVKIVKAGSRTLKDAVNEALRDWVTNVKTTHYIIGSALGPHPFPMIVRDFQSVIGEEVKQQILEIEGKLPDVIVACVGGGSNAIGIFYPFIEDTQVRLVGVEAGGYGIETGMHAASINGGTIGVLHGMKSYFIQDEWGQIESTHSISAGLDYPGVGPEHAFLKEIKRAEYITATDEEALEGFLLLSRTEGIIPALESSHAIIKAVEIAKSLDKSKSVVINLSGRGDKDVQSVKNLLDTDKELYERLLSRLKEKYGV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ASM_MOUSE
Sequence: MPHHRASSGQDHLRAGWEQRLERSLPAPRVGLLWMGLGLALVLALFDSTVLWVPARAYPLPSEGHSVKFSAIAPPLQSAFGWQNLTCPACKVLFTALNHGLKKEPNVARVGSVAIKICKMLNIAPLDVCQSAVHLFEDDVVEVWTRSVLSPSEACGLLLGSSCGHWDIFSTWNISLPSVPKPPPKPPSPPAPGAPVSRVLFLTDLHWDHEYLEGTDPYCADPLCCRRGSGWPPNSQKGAGFWGEYSKCDLPLRTLESLLKGLGPAGPFEMVYWTGDIPAHDVWQQSRQDQLRALTTITDLVRKFLGPVPVYPAVGNHESTPVNGFPPPFIKGNQSSQWLYEAMAKAWEPWLPADALHTLRIGGFYALTPRPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVEELQAAENRGDKVHIIGHIPPGHCLKSWSWNYYKIIARYENTLAGQFFGHTHVDEFEIFYDEETLSRPLAVAFLAPSATTFINLNPGYRVYQIDGNYPGSSHVVLDHETYILNLTQANAAGGTPSWKRLYRARETYGLPDAMPASWHNLVYRMRDDEQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSARADSPALCRHLMPNGSLPDANRLWSRPLLC
What is the function of this protein?
(Microbial infection) Secretion is activated by bacteria such as P.  aeruginos, this activation results in the release of ceramide in the outer leaflet of the plasma membrane which facilitates the infection.
What are the official names of this protein?
Sphingomyelin phosphodiesterase, Acid sphingomyelinase, ASMase.
What is the protein family that this protein belongs to?
Belongs to the acid sphingomyelinase family.
What are the subcellular locations of this protein?
Lysosome. Lipid droplet. Secreted. Note=The secreted form is induced in a time- and dose-dependent by IL1B and TNF as well as stress and viral infection. This increase of the secreted form seems to be due to exocytosis of the lysosomal form and is Ca(2+)-dependent. Secretion is dependent of phosphorylation at Ser-506. Secretion is induced by inflammatory mediators such as IL1B, IFNG or TNF as well as infection with bacteria and viruses.
Protein: SYV_BRADU
Sequence: MIEKNYQPADIEARMSVVWEDSLAFKAGRPDRRDAVPFTIVIPPPNVTGSLHMGHALNNTLQDILCRFERMRGRDVLWQPGTDHAGIATQMVVERQLMERQQPGRREMGREKFLERVWQWKAESGDTIINQLKRLGASCDWSRERFTMDEGLSKAVIKVFVELHRDGLIYKDKRLVNWDTKLLTAISDLEVQQTEVKGSLWYLRYPIEGKTFSPEDPSSFIVVATTRPETMLGDTGVAVHPDDERYQKLIGKHVILPLVGRKVEIVADDYSDPEKGSGAVKVTPAHDFNDFEVGNRHGLRRISVLDKEGCLDLLDNEDYLRDLPEGAAQFAEEFNKVDRFVARKRIVERLESFGFVERIEPHTHMVPHGDRSNSVIEPYLTDQWYVDAKTLAKPAIAAVRSGETSFVPKNWEKTYFEWMENIQPWCISRQLWWGHQIPAWYGPDGKVFVAETEEEAISHALGYYVEQEVITAEQGREMALDRNKREGFITRDEDVLDTWFSSALWPFSTLGWPEDAPEVQRYYPTNALVTGFDIIFFWVARMMMMGLHFMKEVPFSTIYIHALVRDEKGAKMSKSKGNVIDPLHLIDEYGADALRFTLAAMAAQGRDIKLATSRVEGYRNFATKLWNASRFAEMNHCAVPEGFEPAKAKETLNRWIAHESAHTTREVTEAIEAYRFNDAAGAIYRFVWNVYCDWYVELAKPVLLGPDSPAKDETRAMVAWARDEILKLLHPFMPFITEELWEVTAKRDGLLALAAWPLKPAEPTPEQLAMFAAAAGPTDPLISPALIVPIFDHADFTDPKAEAEIGWVIDLVTQIRSVRAEMNIPPATLTALVLAGASAETRERAPRWTDVIKRMARLSDISFADRAPDGAVQLLVRGEVAALPLKGVIDVAAERTRLDKEIGKADADIKRAESKLANEKFVANAAEEVVEEEREKREAALARKAKLLEALERLKQAS
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_FRASN
Sequence: MKATKETLSPTRVKLTVEVPFDELKPSVDATYRKLARQVRVSGFRPGKVPPRILDQRLGRGVILDEAIQEALPRLYSEAVQAEEVDVLSRPEVDITEFADGAQLVFTAEMDVRPEVTLPEFGELELVVEPATVTDEQVEEHLTNLRDRFAVLKPVERPVQEGDFVSLDLSASVDGEAIEDATATGMSYEVGSGNLIDGIDEAIAGASDGDERTFDTELLAGEYTGRTAQVTAVVRGVKEKELPELDDDFATTASEFDTLEELRADVRTRLESNRKVEQLGEARDKMLDKLIELVEVPVPDSVLAGELEAREHRLGHELEHIGTDRATYLETLGQSAEEFDAEVRSSAGKAIRSQFILDAVIDAESIGLDQGELMEQILMRAQRAGVQPDQYAQQLAQGEGLTALMADVLRTKALFLLLENAKVVDTEGNAVELNLPRRPSGEAEDDVRDISDELDAEELEVPAAAPSAEVTAAAGDEATATATATDADTATDADGAGDSELPASETK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: DNAA_NATTJ
Sequence: MSENMEELWSKTLEELKQQLSKPSFETWFQSTEPVEMSSTDLYISVPNEFTKDWLNSRYKNSIENSLKKISGKQLKIKFLLPGEKIKMEEQNNENEEKPESTSKKSSQGSEHTTWLNPKYTFDTFVIGNANRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVLSHQPNYRVVYISSEKFTNEFINAIRDNKTVNFRNKYRNVDILLVDDIQFLAGKEQTQEEFFHTFNTLHENDKQIIISSDRPPKEIPTLEDRLRSRFEWGLITDIQAPDLETRIAILRKKAYLEKLDIPNDVIVYIANQIDTNIRELEGGLIRVIAYSSMANKKITKETAEEALKDILPNKQPKKMTVEHIQKTVAQYFGLKVDDLKAKKRTRSVAFPRQIAMYLARELTDSSLPKIGDEFGGRDHTTVMHAHDKIASDLKKESHLNETIDEIKNLLHGD
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_METRJ
Sequence: MTRTALYAGSFDPVTNGHLDVVRQACRLVDRLVIAIGVHPGKAPLFSAEERAALLTETCGPVAQAEGAALEIVTFNDLAVSAARRCGAAIFIRGLRDGTDLDYEMQLAGMNGAMAPEVQTVFLPASTQARPITATLVRQIAGMGGDVSPFVPAAVAARLRQRFAAHS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAG_XANAC
Sequence: MQDDPRYRVEVEVSPRFLAHQSTPDEGRYAFAYSIRIQNAGAVPARLVARHWQITDGNGRTEQVDGEGVVGEQPWLRPGEAFHYTSGVLLETEQGQMQGHYDMVADDGTEFIAPIAAFVLSVPRTLH
What are the official names of this protein?
Protein ApaG.
Protein: TSAD_CERSK
Sequence: MSRPLTFLGIESSCDDTAAAVVRADGARAEILSSVVDGQTALHAAFGGVVPEIAARAHAERLDLCVERALEEAGLGLRDLDGIAVTAGPGLIGGVLSGVMLAKGLAAGTGLPLVGVNHLAGHALTPRLTDGLAFPYLMLLVSGGHCQFLIARGAEEFSRLGGSIDDAPGEAFDKTAKLLGLPQPGGPSVEAEAATGDPRRFAFPRPMLDRPGCDMSFSGLKTALLRARDGLVAEKGGLTRADRADLCAGFQAAVVEVLAEKTRRALAVYAAEGAAEPALAVAGGVAANGPIRAALTSVAEAAGVRFLAPPLRLCTDNAAMIAWAGIERFRAGGRDGMELSARPRWPLDRSAPALIGSGRKGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDPI_BACSU
Sequence: MKKNIISIIIVCLSFLTSIILYQYLPEEIPIQWSGNKPAAIVSKPLTIFIIPVVMLIYYLTFYMLTIKSTQKNKALLFLASNNMLILLYILQLSTLLISLGYEVNIDLIIGLGVGIFLIIGGNSMQLAEQNHLIGLRTPWTLKDETVWKLGNRFASKVLVVCGFIIAVLSFFTGEYIILIMIVLVLLALVISTLASYHYYKKLNGSR
What is the function of this protein?
Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor/signal transduction protein as well.  Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane.
What are the official names of this protein?
Immunity protein SdpI.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS14Z_ALIB4
Sequence: MAKKSMIAKQQRTPKFAVRAYTRCSVCGRPHSVYRDFGLCRVCLRKMANEGLLPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: CLPS_ECOSM
Sequence: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: REP5_ECOLX
Sequence: MNQSFISDILYADIESKAKELTVNSNNTVQPVALMRLGVFVPKPSKSKGESKEIDATKAFSQLEIAKAEGYDDIKITGPRLDMDTDFKTWIGVIYAFSKYGLSSNTIQLSFQEFAKACGFPSKRLDAKLRLTIHESLGRLRNKGIAFKRGKDAKGGYQTGLLKVGRFDADLDLIELEADSKLWELFQLDYRVLLQHHALRALPKKEAAQAIYTFIESLPQNPLPLSFARIRERLALQSAVGEQNRIIKKAIEQLKTIGYLDCSIEKKGRESFVIVHSRNPKLKLPE
What is the function of this protein?
RepA is essential for origin function, autoregulates its own synthesis from the promoter, and, when overproduced, blocks origin function.
What are the official names of this protein?
Replication protein RepA.
What is the protein family that this protein belongs to?
Belongs to the initiator RepB protein family.
Protein: SERC_STRT2
Sequence: MTIYNFSAGPATLPKPVLEKAQAELLNYQDSGMSVLEMSHRSPEFDKIIKDAEATLRELMAIPDNYKVIFLQGGASTQFTMVPLNLAQGKKAYYLVGGSWGKKAYTEAVKLSKTIPFEPILLASSEDTVYDHIPSFDPSTIDPEAAYVHLTTNNTIEGTSIYDLPDTNGVPIVAHMSSNILAARYNVEDFALIYAGAQKNIGPAGVTVVIVREDFLNDQPQLSAMLDYRIQAEAGSLYNTPPCFNIYISKLVFDWVKNEIGGVDKMAEIQREKSGLLYDYIESSDFYTNPVKDAKDRSVCNIPFVTPSKDLDAKFVAEADALGFKNIKGHRSVGGMRASVYNAFPRQGVLDLIDFMKKFEDENK
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_GLAP5
Sequence: MNQLDALRQMTVVVADTGDIDAIKAYQPEDATTNPSLVLSASALPQYAPLIDEAIAYAKAKSNDKAQQLIDAEDKLAVNIGLEILKVVKGRISTEVDARYSYDTEKTIAKARKLIALYNEAGISNDRILIKIASTWQGIKAAEQLEKEGINCNLTLLFSQAQARACAEAGVYLISPFVGRILDWYKANSDKKEYAPAEDPGVVSVTSIYNYYKQHGYNTVVMGASFRNAGEITELAGCDRLTIAPALLKELQESEAPLVRKLEYKGEVKARPAPMTEAEFYWEHNQDPMAVEKLAEGIRKFAIDQEKLEAMLLAKF
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.