PharMolix/UniProtQA huggingface dataset:
Protein: APAH_SHIFL
Sequence: MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGEAAAS
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: RSMH_METEA
Sequence: MSRAPRTARAELPKGEQARHVPVLLAEVLAALSLDRPGLAVDGTFGAGGYTRALLEAGPEVRVIAIDRDPTAIRGGADLVTASGGRLRLVQGRFGDLDTLIADQDEAQADWIVLDIGVSSMQIDEAQRGFSFRQDGPLDMRMGGEGPSAADLVNGEEETTLADILYHFGEERRSRAVARAIVEARRRAPIETTAQLADLVAGVVRPEPGSPIHPATRSFQGLRIAVNDELGELVRGLHAAERVLKPGGRLAVVTFHSLEDRIVKQFFSARSGRAAQASRHVPGVERPAPKSFKLVTKGPVLPSEAETDVNPRSRSAKLRAGERTDAPAPPPLSAIEMLASLPAPQGRGPRR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_STRP8
Sequence: MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGGVVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFAWANHLPLIPVNHMAGHLMAAREQEPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETRDDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSAFINVHHNAKQKGDELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQGLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQFPDSFVIN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_ANAPZ
Sequence: MARVKRGVTTRARHKKVIALAKGYRGRSKNCYRAALQRLEKALAYAYRDRRARKRDFRSLWIVRINAAAGLYGLRYSEFMHGVSLCSIGLNRKMLAEMAVRDKGAFEKIAHAAAQACGRTCVVAQSNS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: FBP1L_XENTR
Sequence: MSWGTELWDQFDNLEKHTQWGIDFLDKYAKFVKERLEIEQNYAKQLRNLVKKYCPKRSAKDEEPRFTSCLSFYNILNELNDYAGQREVVAEEMGHRVYAEIMRYSNDIKGERKSHLQEGRKAQQYLDMCLKQMDNSKRKFERECREAEKAQQTYERLDNDSNATKSDVEKAKQQLHLRTHMADESKNEYAAQLQNYNAEQHKHFYIVIPQVYKHLQEMDERRTVKLSECYKGFADAERKVIPIISKCLEGMVQAAKSVDERRDSQIVVDCFKSGFEPNGDYPFEDYSQHIYRTVSDGTISTPKQESLKPDPRVTVGKAKGKLWLFGKKPKGPALEDFSHLPPEQRRKRLQQRIDELSRELQKEMDQKDALNKMKDVYEKNPQMGDPSSLHPKIAETTSNIERLRMEIHKNEAWLSEVEGKVSQRSERRHSAEANHLVAQGRESPEGSYTEDANQEGRVQPQPHAHPEFDDEFDDDEPLPAIGHCKSLYPFDGNNEGTLAMKEGEVLYIIEEDKGDGWTRARKQNGEEGYVPTSYIDITLEKNSKGAVTYI
What is the function of this protein?
Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis.  Promotes cdc42-induced actin polymerization by activating the wasl-waspip complex, the predominant form of wasl/n-wasp in cells.  Essential for autophagy of intracellular bacterial pathogens (By similarity).
What are the official names of this protein?
Formin-binding protein 1-like, Transducer of Cdc42-dependent actin assembly protein 1, Toca-1.
What is the protein family that this protein belongs to?
Belongs to the FNBP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cytoplasmic vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ADA28_MACFA
Sequence: MLQALLTVSLLLSPVPVSAIKELPGVKKYEVVYPIRLHPLHKREVKEPEQQEQFETELKYKMTVNGKIAVLYLKKNKNLLAPGYTETYYNSTGKEITTSPQIMDDCYYQGHIINEKDSDASISTCRGLRGYFSQGNQRYFIEPLSPIHRDGQEHALFKYDPEEKNYDSTCGTDGVLWVHDLQNIARPATRLVKLNDGKVQKHEKYIEYYLVLDNGEFKKYNENQDEIRKRVFEMANYVNMLYKKLNTHVALVGMEIWTDEDKINITPNASFTLENFSKWRGSVLPRRKRHDIAQLITATEFAGMTVGLAFMSTMCSPYHSVGVVQDHSDNLLRVAGTMAHEMGHNFGMFHDNYSCKCPSTICVMDKALSFYIPTDFSSCSRVSYDKFFEDKLSNCLFNAPLPTDIISTPICGNQMVEMGEDCDCGTSEECTNICCDAKTCKIKAGFQCTSGECCEKCQFKKAGMVCRPAKDECDLPEMCDGKSGNCPDDRFRANGFPCHHGKGYCLMGACPTLQEQCTELWGPGTKVADQSCYNRNEGGSKYGYCRRVDDTLIPCKTNDTMCGKLFCQGGSDNLPWKGRIVTFLTCKTFDPEDTSEEIGMVANGTKCGHNKVCINAECVDIEKAYKSTNCSSKCKGHAVCDHELQCQCEEGWSPPDCDDSSVVFYFSIVVAVLFPVAVISLVVAIVIRQQSSREKQKKDQRPLSTTGTRPHKQKRKPQMVKAVQPQEMSQMKLHVYDLPVEGNEPPASFLISKPDFSPPPIPAPRSSSFLDSNPKA
What is the function of this protein?
May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L.  May be involved in sperm maturation.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 28, ADAM 28, Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II, eMDC II.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PEPT_YERPG
Sequence: MDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMATLPANVSWPVPTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNVPHGDIRIAFTPDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGVMVNALSLATRYHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKRVGKGLHRDCYIEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRISELTAKRAKES
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MF13A_BOVIN
Sequence: MRLGGPWAWLLGLPTAVVYGSLALFVSVLHNVFLLYYVDTFVSVYKIDKAAFWVGETVFLLWNSLNDPLFGWLSDRQFLSSQPRSGAGLSSRAVVLARVRALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSAHDRTHLNFYCSLFSAAGSLSVFASYAFWNKEDFSSFRAFCLALATGSGLGFVGAARLLRRRVEAAGREPGCPAMAVNDGLCEEELLVGGEEAGSITLGQYLQQLARHRNFLWFVGMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSFLLGISYVAPHLNNLYFLPLCRRWGVYAVVRGLFLLKLGLSLLMLLAGPDHPGLLCLFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQHPPAPVGSAQPWPEPPAPPPAQAPPLRQGCFYLLVLVPIACALLQLFTWSQFTLHGRRLHMVKAQRQSLSRAQTLDVKMV
What are the official names of this protein?
Transmembrane protein 180, Major facilitator superfamily domain-containing 13A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: URE3_SPOPA
Sequence: MHLNPAEKEKLQIFLASELLLRRKARGLKLNYPEAVAIITSFIMEGARDGKTVAMLMEEGKHVLTRDDVMEGVPEMIDDIQAEATFPDGTKLVTVHNPIS
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_SHEON
Sequence: MSNVRYISNLTRETYALILAGGRGSRLHELTDWRAKPALYFGGKFRIIDFPLSNCINSGIRRVGVVTQYKSHSLIRHVMRGWGHFKKELGESVEILPASQRYSENWYQGTADAVFQNIDIIRHELPKYVMVLSGDHVYRMDYAGLLAAHAESGADMTVSCLEVPVAEAAGAFGVMEVDDDMRILGFEEKPQLPKHCPGNPEKCLASMGNYVFNTEFLFEQLKKDAQNAESDRDFGKDIIPSIIEKHKVFAYPFKSAFPNEQAYWRDVGTLDSFWLANMELLSPTPALNLYDAKWPIWTYQEQLPPAKFVFDDDDRRGMAVDSIISGGCIISGATVRRSVLFNEVRVCSYSVVEDSVVLPDVVVLRHCKIKNAIIDRGCIIPEGTVIGYNHDHDRAKGFRVSEKGITLVTRDMLGLPVGYE
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: PANC_ECOL6
Sequence: MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIRKMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAGERDLDEIIAIAGQELNEKGFRADDIQIRDADTLLEVSENSKRAVILVAAWLGDARLIDNKMVELA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y318_BORBU
Sequence: MVEFKNIVKYFPDIDKPILDSINLKIGEVKIFTVVGKNGEGKSTLAKIIAGLIEFDEGEILVNGIKQKNWNVDKAKNNGIYLVSQVPNLKMNLRVWEYLSIYWFGYEFFMPMNKSKTYKYYRWLMQFYKISFDLDKKIKDLNIKEIYFLLIIAALKENAKIIIFDESAAYFSQKEAQAFIKLLVLLKKSGVASLFITHSEITDAIKFSDEFIILKDGKCFRTVNKESILSKLESSSDKVFVANINCNKFEKDPIKFNLFFEDFWKYDVSFSLNKRGVLGIIGEEAVIKTWEKLFLGELLFVGCIKIDGIRYERINIFECKAGFLPLGIGNLFPDNSSILDNFLAKFMNFENKIFIRQSYINQIKDFFKKKMEFYSEEKIYRILYSKSLAFSGGTLKKFALYREMYIAKSFLICFSPLSNLDHKAYNEMSVAIRNYSKEKPVLLITSNLDELLLLSDNILAMKMGEVLLNVSREKISKEKLKELLFL
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein BB_0318.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: SSRP_PSYWF
Sequence: MAKKTKKPSNQIAANKKARHEYFIEETYEAGLVLQGWEVKAIRAGKMSITEAYVVFRGNEAFLFGAHIQPLLSSSTHVDPDSIRTRKLLLNRKEIDTLFGAVNQKGYACVPLEVYWKDSLVKCKIGLAKGKKLHDKRKTLKDRDWERDKERGFKQHLD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: OTC_LISIN
Sequence: MTMYVKSNTTGKDMLSLLEWNKEELIDIIKLAVAMKTNPAHYSHILSGKILGMIFDKPSTRTRVSFEAGILQLGGQAIVMSSKELQIGRGEPIKDTAHVMSEYIDAIMIRTFSHEKVEELAYHAEIPIINGLTDLHHPCQALADLMTIYEWKDQLEGVKLAYIGDGNNVCHSLLLAGAMVGLDIRLAMPKGYEVDETILATAENLAKESGAKIFVTEDPKHAVTDADFIYTDVWTSMGQEEENAKRLADFGEKYQVNAELASIAKPDYHFLHCLPAHREEEVTAEIIDGNHSVIYQQAGNRLHAQKALLAAILEAK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHRD1_CAEEL
Sequence: MVDESKLQCYHKGCGLLFDPKENDNEACTYHPGGPYFHDAYKIWTCCDKKSTDFGTWMNYKGCTRGKHSNEKPVDIVKVAAVKEIRPEKEEDVIVWKGLNKSGKLDSKDATKRIEQNLNVEVTPGATAAIEKKLKEISEAAQSADIQIGAPCRNNGCSTEFDGSKNKENCQHHPGAAIFHEGMKYWSCCNKKTSNFGAFLEQVGCTSGEHKFRNNEIVSKFREDWFSSNGFVTINVYCRGALPETANIVSDGHTVRVSMKHGFGNASVDLDYDLWDEVIPEESRVVIGERKVEISLKQKHGTGWPRLKFDPELDAKNDEEA
What is the function of this protein?
Regulates centrosome duplication (By similarity).  Controls the secretion of the tyrosine kinase receptor let-23/EGFR from the endoplasmic reticulum and is required for the localization of let-23/EGFR to the plasma membrane of vulval precursor cells (PubMed:32053105).  It thus plays a role in positively regulating let/EGFR signaling, and anchor cell and vulval precursor cell alignment (PubMed:32053105).  Plays a role in vulval development and morphogenesis (PubMed:10571178, PubMed:32053105).
What are the official names of this protein?
Cysteine and histidine-rich domain-containing protein 1, CHORD domain-containing protein 1, CHORD-containing protein 1, Protein CHORD.
Protein: PLA1A_DANRE
Sequence: MAWKWIKAFVYLSVCVTSALGDDEEASASKCADFNNTTWLEYRQATKLQVQYLLLTRKNANCASLFTQDCLNHTQKHTAYFNSSLPTKVIVHGYRALGSKPSWVSGLAQALLREEDVNVLVVDWVYGASFAYNLVVENYKEVAVQISVLINQLTKYGSTLESFHFIGVSLGAHVSGFVGTLFHGKLGRITGLDPAGPMFKSADPFDRLDSSDALFVEAIHTDSDYFGISIPVGHVDFFLNGGMDQAGCARSRFASMYGYVICDHMRALHVYMSALNGSCPLIGFPCSGYEEFLAGKCITCDDPFNGTCPQIGLLKNSGITATPLPNQEKVYLLTTASGPFCAHHILVELNVSRLDKTAEVQLILKSIGHPETELNLKLYTDETRYKTVAAHPEQLCKIDSMQLINTGGRFYRQGDIHFEYICISEIPQTRGMDPLCVKNIHIGRGVPWSHDFVQVC
What is the function of this protein?
Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids.  Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI).
What are the official names of this protein?
Phospholipase A1 member A.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PPBI_MOUSE
Sequence: MQGPWVLLLLGLRLQLSLSVIPVEEENPAFWNKKAAEALDAAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPETPLAMDRFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGLSAAARFDQCNTTFGNEVFSVMYRAKKAGKSVGVVTTTRVQHASPSGTYVHTVNRNWYGDADMPASALREGCKDIATQLISNMDINVILGGGRKYMFPAGTPDPEYPNDANETGTRLDGRNLVQEWLSKHQGSQYVWNREQLIQKAQDPSVTYLMGLFEPVDTKFDIQRDPLMDPSLKDMTETAVKVLSRNPKGFYLFVEGGRIDRGHHLGTAYLALTEAVMFDLAIERASQLTSERDTLTIVTADHSHVFSFGGYTLRGTSIFGLAPLNALDGKPYTSILYGNGPGYVGTGERPNVTAAESSGSSYRRQAAVPVKSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMASAGCLEPYTDCGLAPPADESQTTTTTRQTTITTTTTTTTTTTTPVHNSARSLGPATAPLALALLAGMLMLLLGAPAES
What is the function of this protein?
Alkaline phosphatase that can hydrolyze various phosphate compounds.
What are the official names of this protein?
Intestinal-type alkaline phosphatase, IAP, Intestinal alkaline phosphatase, Alkaline phosphatase 3.
What is the protein family that this protein belongs to?
Belongs to the alkaline phosphatase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: CH60_THIDA
Sequence: MAAKDVRFGDSARHRMVAGVNVLADAVKVTLGPKGRNVVLDRSFGAPTVTKDGVSVAKEIELKDKLENMGAQMVKEVASKTSDVAGDGTTTATVLAQSIVNEGMKFVAAGMNPMDLKRGIDKAVNAITEELKKISKPCTTSKEIAQVGSISANSDAPIGQIIADAMDKVGKEGVITVEDGSGLENELDVVEGMQFDRGYLSPYFINNADKQMAIMDDPFILLFDKKISNIRDLLPVLEQVAKAGKPLMIVAEDVDGEALATLVVNNIRGILKTCAVKAPGFGDRRKAMLEDMAILTGGTVIAEEVGLSLEKATLQDLGRAKRIEVGKENTTIIDGAGDGNAIKGRIAQINKQIEEVTSDYDKEKLQERKAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVPGGGVALLRAKAAAAAIKGDNHDQDAGVKIVLRAIEEPLRQIVKNCGDEPSVVVNKVLEGEGNFGYNAGTSEYGDMVAMGVLDPTKVTRTALQNAASIAGLMLTTDCMVADLPEDKAPAMPMGGGMGDMGGMGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_VESOH
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITKVMAEVRGGEFKDYADIDNAPEERERGITISTAHVEYESEIRHYAHVDCPGHADYIKNMITGAAQMDGAIIVIAATDGPMAQTREHILLSKQVGVPYIVVYMNKADMVDDEELVELVEMEIRELLDEYDFPGDDTPVIFGSALKALEGDISDIGVPSILKLVDALDSYIPTPKRDTDKSFIMPIEDVFSISGRGTVVTGRIEAGVVNIGDELEIVGIKDTKTTTCTGVEMFRKLLSSGEAGDNVGVLLRGTKREEVERGQVLSKPGSIKPHAKFEAEIYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGACQLPDGIEMVMPGDNVKMRVELLSPIAMEDGLRFAIREGGRTVGAGVVSKVTD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_BIFAA
Sequence: MPSATESKPETRKVVSIVGPTASGKTGLGIAIAKALEAKGEQAEIVNADAYQMYKGMDIGTAKASPEEQAEVRHHLIDIIEPDDAMSVARFQEIARAKIAELQAREVRPILVGGSGLYARAAIDDISFPGTDPEVRKRLEEREKVEGAGALFDELKTKDPEAAARMDPHNPRRTIRALEVIEVTGRPYSASLPHYRYVIPTVQIGLDLPREELDRRIDIRTKQMLENGFVEEVERIRPRLGITAGKALGYQQVVDYLDGLCDLNDTFMSIAQKTKRLARKQMGWFGRDPRIHWLQALNPALLGNAMAIIEHADAGDYDAIDAQADAYTQHHLGDIA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: DEXH5_ARATH
Sequence: MTNRLPPSLYVPPHQRLGSDYGFNPVPLSPVRYVSAYDDRVSEDRQPQEGTFHCADLDDWNKRFSMLLKDSLKQEVISREKKDRRDFDKLAALATTLGLYSHAYAKVVVFSKIPLPNYRFDLDDKKPQREVNLHTDLLQRVEAYLTEYLSKSSNRIDRVPANSVSRTSSISSTDEWFSEQPLPISATKILWQRSLQLRDRQQYWQASVEGQRMLDSRTSLPAFKQRHSVLTAISQNQVIVISGETGCGKTTQIPQFILESEIEANRGAFSSIICTQPRRISAMSVSERVAYERGEQLGESVGYKVRLEGVKGRDTRLLFCTTGILLRRLLVDRNLRGVTHVIVDEIHERGMNEDFLLIILKDLLSRRSELKLILMSATLDAELFSSYFGGAGVIYIPGFTYPVRSHFLEDILEMTRYRLTPYNQIDDYGQERTWKMNKQIPKKRKSQITFVVEDALRAADFKEFSPETRESLSCWYPDCIGFNLIEFLLCNICENEGPGGILIFLTGWDDISSLKEKLQIHPIFGNPDLVMLLACHGSMETFEQRLIFEEPASGVRKIVLATNIAETSITINDVAFVIDCGKAKETSYDALNNTPCLLPSWISKVSAQQRRGRAGRVRPGQCYHLYPKCVYDAFAEYQLPEILRTPLHSLCLQIKSLNLGSISEFLSRALQSPELLAVQKAIAFLKIIGALDENEDLTTLGRYLSKLPMEPKLGKMLILGAILGCLDPILTVAAGLSVRDPFLTPQDKKDLAEAAKSQFSRDHSDHLALVRAYEGWKKAEEESAVYDYCWKNFLSIQSLRAIDSLRKEFFSLLKDTGLIDGNPSICNSEGNDANLTRAVICYGMYPGICSVVHNERSFSLKTMEDGQVLLYSNSENARETKIPYPWLVFNEKIKVNSVFLRDSTACSDSTLILFGGSISKGDTDGHLKMLGGYLEFFMKPDVAEIYQTLKKELDELIQNKLLNPKVDMQAHRELLSAIRLLVSEDGCDGRFVFGHQILRPLEISALSTKPSLFSRTESGPGGDNSKSQLQTILTRAGYTVPMYKTKQLKNNKFQTTVEFNETQIMGQPCSNKKSAEKDAAAEAIQWLKGGAKESHEQVNHMSKLLKKGKKDHL
What are the official names of this protein?
DExH-box ATP-dependent RNA helicase DExH5, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the DExH box helicase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SUCC_MARMS
Sequence: MNLHEYQAKQLFAEYGLPVSTGYAVDTPEAAVEAAKKIGGNKWVVKAQVHAGGRGKAGGVKLVDSYEEVAAFTQNWLGKNLVTYQTDANGQPVAKILVESCTDIANELYLGAVVDRSTRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPLVGAQPYQARELAFKLGLNPTQIKQFTKVFLGLSQMFHDYDFALLEINPLVITDEGNLHCLDGKIGIDSNAVYRQKKMQEFHDPSQEDEREAHAAKWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVEQVGVNVPVVVRLEGTNAEKGREVLANSGLDIIAATSLKDAAEQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: CU109_IXORI
Sequence: QLAEQYPPHPYSFSYDATDETGARISTSESGDESNSKTGSYSYQTPDGVYRTVNYVADATGFHASIDTNEPGTKSEAPADVTINANPIEVKEAYAFKAKSAA
What is the function of this protein?
Component of the cuticle of the tick.  Binds chitin.
What are the official names of this protein?
Cuticle protein 10.9, Ir-ACP10.9.
Protein: PXL2B_DANRE
Sequence: MSSVNLTSLGANQLKNTTTGEMVEIGSLWREQAVVLFFLRRFGCQVCRWMAAEVSKLEKDLKAHGIALVGIGPEETGVKEFKDGGFFKGDIYIDEMKQCYKDLGFKRYNAINVVPAAMGKKVREIASKASAEGIQGNFSGDLLQSGGMLIVAKGGEKVLLHFIQKSPADNPPLEEITKALGISANVQAGEKPQCNEDVCTR
What is the function of this protein?
Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor.  Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity).
What are the official names of this protein?
Prostamide/prostaglandin F synthase, Prostamide/PG F synthase, Prostamide/PGF synthase, Peroxiredoxin-like 2B.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin-like PRXL2 family. Prostamide/prostaglandin F synthase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: H2AV_CAEEL
Sequence: MAGGKGKAGKDSGKSKSKVVSRSARAGLQFPVGRIHRFLKQRTTSSGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLHLAIRGDEELDTLIKATIAGGGVIPHIHRYLMNKKGAPVPGKPGAPGQGPQ
What is the function of this protein?
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).  Required to maintain non-distal tip cell (DTC) fate of somatic gonadal cells through the repression of transcription factor ceh-22 (PubMed:24346701).
What are the official names of this protein?
Histone H2A.V, H2A.F/Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.