PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_LAWIP
Sequence: MLCLGIETSCDETAVALVENGKCIGSILGTQAPLHALFGGVVPELASREHYRCLGPLYDKLMEDAKVTLADLDVIAVTRGPGLLGALLVGLAFAKGLALASGKTLIGINHLHAHLLVAAIEEPIEYPALGLLVSGGHTHIYKIDAPDIFILLARTLDDAAGEACDKFAKMLGLPYPGGVIIDKLAQQGIPDPYLFPRPYIHNSELDFSFSGLKTSAAMYLKQYPQLIEEGQRYCSNNSKVAIKEELYNVCSSYLLAISETLYIKMERALQKYTNEIKTIIVAGGLAANSFVRQAMHNLAINYNKKILLPEQKLCTDNAVMIAYYGELLAEKGYCHRLDLSAIPRGQHIPDDMVKV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_SYNP2
Sequence: MTQNPQWLWQEVLTKLEQQLSRPTYETWIQPTAIQQWREDEIVLCAPNAFVLNHIQKYYGALITETIAELLQQPVKVRLTSPEGNTLAATQSFYSSRSGQSTRPGKKTPELNSKYTFSRFVVGPTNRMAHAAALAVAESPGRDFNPLVLCGGVGLGKTHLMQAIGHYRLDTQPDAKIFYVSTEQFTNDLIVAIRKDSLQTFREHYRTADILLVDDIQFIEGKEYTQEEFFYTFNTLHEAGKQIVLASDRPPHQIPGLQQRLSSRFSMGLIADIQPPDLETRMAILQKKAEAENLNLSRSVIEYIATHYTANIRELEGALLRAVTHIAISGLPMTVENLAPILNPTVEYAPAAPDVILQIAAEATGVSIEDLKGASRRREISTARQIAMYLMRQHTDLSLPRIGELFGGKDHTTVMYSCDKIGQLLTKNQKISQLVSQISDRINHHHQNL
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1147_MYCPA
Sequence: MTGPGELAGSRPVDAHLENGAGIDVVLVTGLSGAGRGTAAKVLEDLGWYVADNLPPQLITRMVDLGMDAGSRITQLAVVMDVRSRGFTGDLDSVRTELATRNIAPRVVFMEASDDMLVRRYEQNRRSHPLQGDQTLAEGIAAERRMLAPVRATADLIIDTSTLSVRALRETIERAFGGGANATISVTVESFGFKYGLPMDADMVMDVRFLPNPHWVDELRPRTGQDPAVRDYVLGQPGAAEFLDAYHRLLSLVVDGYRREGKRYMTVAIGCTGGKHRSVAIAEALMQRLQAQHGEAQLSVRVLHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein MAP_1147.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: PYRB_LACJO
Sequence: MENLNLVSLPHFVSVENLSVEEVEALINRAEYFKNGGATPNLTEPIYITNMFFEDSSRTHTSFEMAERKLGLTVIPFDPAHSSVNKGETLYDTSLIMEAVGVNIEVIRHSQNEYYQNLIRPQNHQHLDIGIINAGDGSGQHPSQCLLDMMTIHEHFKQFKGLKVAIVGDITNSRVAKSNMELLHRLGAEVYFSGPEYWYSKEFDKYGKYEELDKLISEMDVMMLLRVQHERHSDDPNEKNFDAKAYHEKYGINNQRYQELKPNAIIMHPGPINHDVELSANLVESDKCMFTRQMQNGVFMRMAMIEAVLRGRKLGGLK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: REGX3_MYCBO
Sequence: MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
What is the function of this protein?
Member of the two-component regulatory system SenX3/RegX3 (PubMed:11101667).  Specifically binds to the promoter region of the senX3-regX3 operon (PubMed:11101667).
What are the official names of this protein?
Sensory transduction protein RegX3.
Protein: NECA1_RAT
Sequence: MEDSRETSPSSNNSSEELSSALQLSKGMSIFLDILRRADKNDDGKLSFEEFKAYFADGVLSGEELHELFHTIDTHNTNNLDTEELCEYFSQHLGEYENVLAALEDLNLSILKAMGKTKKDYQEASNLEQFVTRFLLKETLNQLQSLQNSLECAMETTEEQTRQERQGPSKPEVLSIQWPGKRSSRRVQRHNSFSPNSPQFNVSSPALLEEDNQWMTQINRLQKLIDRLEKKDLKLEPLEEEVIEENTKPHIMLVQRQMSVTEEDLEEFQLALKHYVESASAQSGCLRISIQKLSNESRYMIYEFWENSSVWNRHLQTNYSKTFQRSNVDFLETPELTSTMLVPASWWILKNN
What are the official names of this protein?
N-terminal EF-hand calcium-binding protein 1, EF-hand calcium-binding protein 1, Neuronal calcium-binding protein 1, Synaptotagmin-interacting protein 1, Stip-1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_SHIBS
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAIRGMINAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SYFA_YERPS
Sequence: MPHLAELVAKAKAAVEDAQDIAALDLVRVEYLGKKGHLTLQMTSLRELPAEERPAAGAVINQAKQEVQEALNARKEKLESAVLNARLAAETIDVSLPGRRMENGGLHPVTRTIERIETFFGELGFSVESGPEIEDDYHNFDALNIPAHHPARADHDTFWFDATRLLRTQTSGVQIRTMQEQQPPIRIIVPGRVYRNDYDQTHTPMFHQMEGLIVDRDISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_ENT38
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDDDFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDAQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADREQLFLSAGTRIVELTKRYYEQDDASALPRNIANKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTPKYHMEDVHRAGGVLGILGELDRAGLLNREVKNILGLTLPQSLEQYDIMLTKDDAVKSMFRAGPAGIRTTKAFSQNCRWDTLDDDRAEGCIRSLEHAYSQEGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTTFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGNIAIIEDGDLIEIDIPNRGIQLQLSDQEIAARREAQDARGDKAWTPKDRQREVSYALRAYATLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: YQFZ_BACSU
Sequence: MKRLTLVCSIVFILFILFYDLKIGTIPIQDLPVYEASAKTAVQEPAYKTVKVKPGDTVMSIVGSAGSPDDIVKDFEALNPNVKANAIQAGTAYKFPVYP
What are the official names of this protein?
Uncharacterized protein YqfZ.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Single-pass membrane protein.
Protein: WECF_ECOHS
Sequence: MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPSQFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFVKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHVAALRAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLELFSEENLQVLSEKLEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NAT10_ARATH
Sequence: MTNGGGGNNGAANRTEELQPHPVKEQLPGIQYCVNSPPPWLEAVVLGFQHYLLSLGITVLIPSVLVPLMGGGYAEKVKVIQTLLFVSGLTTLFQSFFGTRLPVIAVASYAYIIPITSIIYSTRFTYYTDPFERFVRTMRSIQGALIITGCFQVLICILGVWRNIVRFLSPLSIAPLATFTGLGLYHIGFPLLARCVEVGLPGLILLIFVTQYLPRFLKMKKGVMILDGSRCDRYGMILCIPLVWLFAQLLTSSGVYDHKSHTTQTSCRTDRTGLITNTPWIYIPYPFQWGSPTFDITDSFAMMAASFVTLFESTGLFYASARYGSATPIPPSVVSRGTCWLGVGVLLNGMLGGITGITTSTENVGLLAMTKIGSRRVIQISAAFMIFFSIFGKFGAFFASIPLPIMASLYCIVLCFVSSVGLSYLQFCNLNSFNIKFILGFSFFMAISIPQYFREYYNGGWRSDHHSNWLEDMIRVIFMSHTTVAAIIAIVLDCTLCRDSDEAKKDCGMKWWDKFRLYNLDVRNDEFYGLPCRLNKFFPSH
What are the official names of this protein?
Putative nucleobase-ascorbate transporter 10, AtNAT10.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NU4LC_CARPA
Sequence: MLLEHVLVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNMNFVTFSDFFDKRQLKGDIFSIFVIAIAAAEAAIGSAIVSSIYRNRKSTRINQSTLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HEMH_CAMJD
Sequence: MRLVLFLNMGGAMNLQDCEVFLKNMFNDPYILGIKNRFLRKFVAWIITKARVKAMQENYKKMGGKSPLNELTQSLCDKLNLKQDEFKFDFVNLYVPPFATEILQKYTLNENDEIILFPLYPHHSCTTVTSSLEILQDEISKQKIQAKVKTIDIFYKNKLYNEMIVSHILAKKNKFDAKILIFSAHSLPQSIIDKGDLYEKHVKDHVEILKEKLKDHFDEFILAYQSKLGPVKWLEPNTSDVLANLNDKALIYPISFCIDCSETIFELGMEYKHLAKCDYDLISCPNDSDEFAQFILKYLSDLN
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GADL1_HUMAN
Sequence: MSSDSDRQCPVDGDIDQQEMIPSKKNAVLVDGVVLNGPTTDAKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWRPPEQLKQLLDLEMRDSGEPPHKLLELCRDVIHYSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKKMIEFIGWKEGDGIFNPGGSVSNMYAMNLARYKYCPDIKEKGLSGSPRLILFTSAECHYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVLGAFDPLDEIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAGIQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTLGLEERVNRALALSRYLVDEIKKREGFKLLMEPEYANICFWYIPPSLREMEEGPEFWAKLNLVAPAIKERMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDLLGKDM
What is the function of this protein?
May catalyze the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively.  Does not exhibit any decarboxylation activity toward glutamate.
What are the official names of this protein?
Acidic amino acid decarboxylase GADL1, Aspartate 1-decarboxylase, ADC, HuADC, Cysteine sulfinic acid decarboxylase, CSADC, HuCSADC, Glutamate decarboxylase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: BMF_RAT
Sequence: MEPPQCVEELEDDVFQPEDGEPGTQPGSLLSADLFAQSQLDCPLSRLQLFPLTHCCGPGLRPVSQEDKATQTLSPASPSQGVMLPCGVTEEPQRLFYGNAGYRLPLPASFPAGSALGEQPPEGQFLQHRAEVQIARKLQCIADQFHRLHMQQHQQNRDRAWRQVFLFLQNLALNRRENREGVGPW
What is the function of this protein?
May play a role in apoptosis.
What are the official names of this protein?
Bcl-2-modifying factor.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
Protein: DCTP_PSEAE
Sequence: MLKHTAKALVCALSLTVAGIVQAADPIVIKFSHVVAEHTPKGQGALLFKKLVEERLPGKVKVEVYPNSSLFGDGKEMEALLLGDVQIIAPSLAKFEQYTKKLQIFDLPFLFDNIQAVDRFQQSPQGKELLTSMQDKGITGLGYWHNGMKQLSANKPLREPKDARGLKFRVQASKVLEEQFKAVRANPRKMSFAEVYQGLQTGVVNGTENPWSNIYSQKMHEVQKYITESDHGVLDYMVITNTKFWNGLPEDVRGVLAKTMDEVTVEVNKQAEALNQGDKQRIVEAKTSEIIELTPEQRAEWRKAMQPVWKKFEGEIGADLIKAAEAANQAQ
What is the function of this protein?
Part of the tripartite ATP-independent periplasmic (TRAP) transport system DctPQM involved in C4-dicarboxylates uptake.
What are the official names of this protein?
C4-dicarboxylate-binding periplasmic protein DctP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 7 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUOH_BACCZ
Sequence: MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRFGLLQTVADVLKLLLKEDSIPKAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVGLLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMISYEIPLVMSVIGIVLLAGSLNLNEIVAAQENVWYIFVQPIGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWAFFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPRIRGDQLMEFGWKVLLPIALANIFLTALIKELFF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAPSD_BPKMV
Sequence: MSFLNDLTRPNYAGKNADVDIHLEEHLGIVDKHFAYTSKFAPLMNIRDLRGSNVVRLDRLGNVEAKGRRAGEELERSRVVNDKWNLTVDTLLYLRHQFDHQDEWTQSFDMRKEVAELDGQELARKFDQACLIQVIKAAAMDAPVDLEDAFSPGVLEKLDLTGLTAKQAADKIVRMHRRVVETFIDRDLGDAVYSEGLTPMSPRVFSLLLEHDKLMNVEYQATGATNDYVKSRVAILNGVKVLETPRFATKAIAAHPLGRHFNVSAEESERQIALFLPSKTLITAQVAPVQAKLWEDNEKFSWVLDTFQMYNIGARRPDTAGAIELKGIGAFDITA
What is the function of this protein?
Assembles to form a prolate capsid about 56 nm in length and 41 nm in width.
What are the official names of this protein?
Major capsid protein, Gene product 32, gp32, Major head protein.
What are the subcellular locations of this protein?
Virion.
Protein: GLCDH_THETK
Sequence: MRAVTVTPGVPESLRLREVPEPKPGPGQVLLKPLLVGVCGTDKEIIEGRYGKAPEGSDYLILGHEALAEVAALGKGVDNVSEGDLVVPTVRRPLDCQLPVDYCPPGKYLEHGIWGLHGHAAELSITDAAYLVKVPKELRDIAVLTEPLSVVEKGVELGVESYKARLGSPPKTALVLGAGPVGLLASMVLRLMGVSITAVATRPHDSLKARLVEELGGRYIDAVHERLEGEFDLVIEATGAPSLAVQGLERLAPGGVEVLLGVYPPTGELKGLGSLLTDAVLKNKLVVGSVNAGLRHFERALAHLKEANDSLNGFPKRLITKVVPLERYQEAYVWTHDDIKVVLQVQT
What is the function of this protein?
Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone.  To a lesser extent, is also active with xylose as substrate, but mannose, arabinose, galactose, fructose 6-phosphate, glucose 6-phosphate, glycerinaldehyde 3-phosphate, ribose, sorbitol, ethanol, erythritol, or lactose are not oxidized by the enzyme.  Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+).  Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.
What are the official names of this protein?
Glucose 1-dehydrogenase, GDH, GlcDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
Protein: ASSY_ALCBS
Sequence: MSKINKVVLAYSGGLDTSVIVKWLQDTYDCEVVTFTADIGQGEEVEPARAKAEAMGVKEIYIEDLREEFVRDYVFPMFRANAIYEGEYLLGTSIARPLIAKRLVEIAEETGADAISHGATGKGNDQVRFELGAYALAPGIQVIAPWREWDLNSREKLMAYCEERNIPVDFSNKKKKSPYSMDANLLHISYEGGNLEDPWWEAEEDMWRWSVSPEAAPDQATYITLGFEKGDIVSIDGETLSPADVLTKLNKLGGDNGIGRLDIVENRYVGMKSRGCYETPGGTIMLPAHRAIESLTLDRESAHLKDSVMPKYAELLYNGYWWSPERLALQKLIDATQEHVNGEVRLKLYKGSVTVVGRRSDNDSLFDASIATFEDDAGAYDQKDAEGFIKLNALRLRIAAKTGRKLS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_STRPI
Sequence: MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIFEHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQKPSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQGVKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVAVENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIEGNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIAVLGEGANAKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVESGQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_BACAH
Sequence: MKVTKADIVISAVKPEQYPDGDLPEIALAGRSNVGKSSFINKILNRKKLVRISSKPGKTQTLNFFLINEMMHFVDVPGYGYAKVSKTERAAWGKMIETYFTTREQLDAAVLVVDLRHKPTNDDVMMYDFLKHYDIPTIIIATKADKIPKGKWQKHLKVVKETLDIESGDEVVLFSSETGLGKEEAWKAIHKFTKTKNA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PTH_FRATO
Sequence: MPKIKMIVGLGNIGKEYQDTRHNVGEWFIAKIAQDNNQSFSSNTKLNCNLAKVSIDYNNVVLVFPTTYMNNSGLAVSKVANFYKIAPAEILVAHDELDIDSGEIRLKKGGGHGGHNGLRSINQHLGTNDYLRLRIGIGHPGHKSKVANYVLSNPSIAQKKDIDSAIDNGICFLDDIINYKLEPVMQKLHTK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAJQ_SALPA
Sequence: MPSFDIVSEVDLQEARNGVDNAVREVESRFDFRGVEATIALNDANKTIKVLSESDFQVNQLLDILRAKLLKRGIEGASLDVPDEFVHSSKTWYVEAKLKQGIESAVQKKIVKLIKDSKLKVQAQIQGEEIRVTGKSRDDLQSVMALVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: TUSC3_HUMAN
Sequence: MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNEAATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSDLDFE
What is the function of this protein?
Magnesium transporter.
What are the official names of this protein?
Tumor suppressor candidate 3, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3, Oligosaccharyl transferase subunit TUSC3, Magnesium uptake/transporter TUSC3, Protein N33.
What is the protein family that this protein belongs to?
Belongs to the OST3/OST6 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: S15A4_HUMAN
Sequence: MEGSGGGAGERAPLLGARRAAAAAAAAGAFAGRRAACGAVLLTELLERAAFYGITSNLVLFLNGAPFCWEGAQASEALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGMLAFPLLAAPATRAALCGSARLLNCTAPGPDAAARCCSPATFAGLVLVGLGVATVKANITPFGADQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFVTGYAIPTVCVGLAFVVFLCGQSVFITKPPDGSAFTDMFKILTYSCCSQKRSGERQSNGEGIGVFQQSSKQSLFDSCKMSHGGPFTEEKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYVLQSLHLRIPEISNITTTPHTLPAAWLTMFDAVLILLLIPLKDKLVDPILRRHGLLPSSLKRIAVGMFFVMCSAFAAGILESKRLNLVKEKTINQTIGNVVYHAADLSLWWQVPQYLLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGVGSFVGSGLLALVSIKAIGWMSSHTDFGNINGCYLNYYFFLLAAIQGATLLLFLIISVKYDHHRDHQRSRANGVPTSRRA
What is the function of this protein?
Proton-coupled amino-acid transporter that mediates the transmembrane transport of L-histidine and some di- and tripeptides from inside the lysosome to the cytosol, and plays a key role in innate immune response (PubMed:16289537, PubMed:25238095, PubMed:29224352).  Able to transport a variety of di- and tripeptides, including carnosine and some peptidoglycans (PubMed:29224352, PubMed:31073693).  Transporter activity is pH-dependent and maximized in the acidic lysosomal environment (By similarity).  Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand, and L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate (tri-DAP), the NOD1 ligand (PubMed:25238095, PubMed:29224352).  Required for TLR7, TLR8 and TLR9-mediated type I interferon (IFN-I) productions in plasmacytoid dendritic cells (pDCs) (PubMed:25238095).  Independently of its transporter activity, also promotes the recruitment of innate immune adapter TASL to endolysosome downstream of TLR7, TLR8 and TLR9: TASL recruitment leads to the specific recruitment and activation of IRF5 (PubMed:32433612).  Required for isotype class switch recombination to IgG2c isotype in response to TLR9 stimulation (By similarity).  Required for mast cell secretory-granule homeostasis by limiting mast cell functions and inflammatory responses (By similarity).
What are the official names of this protein?
Solute carrier family 15 member 4, Peptide transporter 4, Peptide/histidine transporter 1, hPHT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Protein: NNR_THEMA
Sequence: MKEIDELTIKEYGVDSRILMERAGISVVLAMEEELGNLSDYRFLVLCGGGNNGGDGFVVARNLLGVVKDVLVVFLGKKKTPDCEYNYGLYKKFGGKVVEQFEPSILNEFDVVVDAIFGTGLRGEITGEYAEIINLVNKSGKVVVSVDVPSGIDSNTGKVLRTAVKADLTVTFGVPKIGHILFPGRDLTGKLKVANIGHPVHLINSINRYVITREMVRSLLPERPRDSHKGTYGKVLIIAGSRLYSGAPVLSGMGSLKVGTGLVKLAVPFPQNLIATSRFPELISVPIDTEKGFFSLQNLQECLELSKDVDVVAIGPGLGNNEHVREFVNEFLKTLEKPAVIDADAINVLDTSVLKERKSPAVLTPHPGEMARLVKKTVGDVKYNYELAEEFAKENDCVLVLKSATTIVTDGEKTLFNITGNTGLSKGGSGDVLTGMIAGFIAQGLSPLEASTVSVYLHGFAAELFEQDERGLTASELLRLIPEAIRRLKE
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.