PharMolix/UniProtQA huggingface dataset:
Protein: SYA_HELMI
Sequence: MEFTGNRVRQLFLEYFEQKGHTIVASSSLVPHNDPTLLFSNAGMNQFKDVFLGFEKRPYLRATTSQKCVRAGGKHNDLDTVGRTARHHTFFEMLGNFSFGDYFKKDAIRYAWEFLTDVCGLPKDKLYATVYLDDDEAFALWRDMIGLPEARILRLGEKDNFWAMGDTGPCGPCSEILIDRGEHLRCKAEECAIGKCDCDRWLEIWNLVFMQYNRDENGTMTPLPRPSIDTGMGLERVTSVLQKVGSNYDTDLLRPLIAFVEQLCGQVYHRDDRGFPFRVIADHIRSCTFLITDGVLPSNEGRGYVLRRILRRAVRFGKVLGIDKPFMYEIVPVVVELMGEAYPDIREKQDFVCKVIKIEEERFHETLHDGMRIAADMVAKVKQEGGNVLPGKQAFTLYDTYGFPLDLAEDIAEENGLTVDKDGFQQAMEAQRERARAARQDTAYGAGMELWAELLQQLGPTVFTGYGRTSGESVVKAIVAGATRVTEAGAGTAVQVVLAETPFYAESGGQIGDSGLLRAGDAVVRVEDTKKMAGGLHVHFGVVAEGVFKEGDQVVAEVESARRLAIARHHSATHLMHKALKEVLGEHVNQAGSLVTPDRLRFDFSHFSPLTRDEWNRIEAAVNRAVFQALPVEVFETSIDEAKAMGATALFGEKYGDRVRVVRMGNYSMELCGGTHLDNTSQVGLCKLLSESGIGAGLRRIEAVTGEAALAYLNEQEETVRMLAEKLKVPAAEVTNRVDSLQAQLREKEREMEQLLSRLAKYQIDDLLAGKEEINGVTVLAAKVQAPDMDALRSMSDLLKEKLGSGVLILGAVAGDKVNLVAAATKDIVGRGVHAGNLVKEAAKVCGGGGGGRPDMAQAGGKDPSRLSDALEAAKKLLKSQIK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_LISW6
Sequence: MKLIAGLGNPGKKYERTRHNVGFMVVDELSFRHQTPWKKSKFNGMVSEINVGGEKMILVKPLTFMNASGECIRPLMDYYNIQVEDVLIVYDDLDLPVGKIRLRQKGSAGGHNGMKSIIQHIKTQEFNRIRVGVSRPLKGEVINYVLGDFPKAEQPDIIAAIQKSADAIEDFAQVPFVEVMNKYN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_RHOCS
Sequence: MAKKSSVEKNKRRRKMVAQQAPKREALRAIARDRTLPPEERFQAVLKLAEMPRNGSKVRIRNRCELTGRPRAYYRKFRLSRVTLRELASTGQIPGMTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: NQOR_SYNAS
Sequence: MKIMVVYYSAYGHVHRLAEAVAEGASEIVDVEVVMRRVPETLPEALLKKIGVFEAQQAFAHVPVCEVAELETADAILFGTPARFGNMCGQMRSFLDATGGLWAKGALVGKVGSVFTSTGTQHGGQESTILSFHTTLLHHGMIIVGLPYTFQGQSRNDEITGCSPYGASTIAGSANDRWPTENELAGANFQGRHVACIAGKLFQ
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: PSBM_PINKO
Sequence: MEVNNLGFIAVLMFLAIPTAFLLIPYVKTASASSGSN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: THIE_LISW6
Sequence: MKEELAVYFIAGTQDIVRGTLPSVLEEALKGGITCFQYREKGAGSLQTASERKEMALECQKLCAKYQVPFIINDDVVLALEIGADGIHVGQNDEEIHQVITSCAGKMKIGLSVHSVSEAEEAERLGAVDYIGVGPIFPTISKADAEPESGTEILKEIRRAGIKLPIVGIGGINEANIAEVLAAGADGVSVISAITRADDYQLVIANLI
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: MUM3_YEAST
Sequence: MGFVDFFETYMVGSRVQFKQLDISDWLSLTPRLLILFGYFYLHSFFTAINQFLQFINTNSFCLRLHLLYDRFWSHVPIIGEYKIRLLSRALTYSKLKIIPTLDKVLEAIEIWFQLHLVEMTFEKKKNVQIFITEGSDDLNFFKDSKFQTTLMICNHRSVNDYTLINYLFLKSCPTKFYTKWEFLQKLRKGEDLAEWPQLKFLGWGKMFNFPRLDLLKNIFFKDETLALSSNELRDILERQNNQAITIFPEVNIMSLELSIIQRKLHQDFPFVINFYNLLYPRFKNFTTLMAAFSSIKNIKRKKNRNNIIKEARYLFHRELDKLVHKSMKMESSKVSDKTTPPMIVDNSYLLTKKEEISSGKPKVVRINPYIYDVTIIYYRVKYTDSGHDHTNGDLRLHKGYQLEQISPTIFEMIQPEMESENNIKDKDPIVVMVNVKKHQIQPLLAYNDESLEKWLENRWIEKDRLIESLQKNIKIETK
What is the function of this protein?
Involved in the organization of the outer spore wall layers and especially in the assembly of the chitosan layer.
What are the official names of this protein?
Protein MUM3, Muddled meiosis protein 3.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PGK1_METAC
Sequence: MSQKTAGKDYLTMDDVELDNKRILLRVDFNSPMDANGNILDDRKIKSHLYTLRSLENSRVVMMSHQGRPGDKDYTTLEAHAKLATELLGRKVTYEDDIFSACARNAIKSLEKGDILLLENTRFYAEENMNRAPEEQARTQMVRKLYPLFDVFINDAFSVSHRSQCSVVGFTEVLPSVAGILMDREITGLDKGLKCHEHPAVFALGGTKAKDIVKVISDILKRGGADRILTTGVVATVFMMAIGIEVGEVNRKFIEDHKYLDQVSIASRLLKEYSGKIIVPKDIALNNDGKREEVKVDKIKGDLPIADIGPETISDYSKFLKEAKLSVFHGPAGIFELESFRLGTEELLKAAAQSNYSIAGGGHTLAAIDQLGLESKYSHLSMGGGASITYLSGEHMPGIEALKNYASRCCKD
What are the official names of this protein?
Phosphoglycerate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C96T1_NARAP
Sequence: MATSSSAWLMFSDHYPEILIAIACFLIFSLLLSARSSSEDSLPYNWPIFGMLPAIISNNQFNDFTTARLRKMGWTFIFKGPWLLDMDYIFTCDPSNINHMFNDNFENYPKGELGKVFDIFGNNIFNADGDLWHDHRKMAQTILWDGNYRTMQATFIRNKMDNALIPILDSAASKRKPVDLQDVFFRFTFDTSCFSVLAADPESLTMEFPAVPFSKAADQALDAALTRHITPRLIWKLKRFFNVGSERTLAVAWKVIDSYIYDKIAELKAKRKLVGKINSYDAVSFYMDNFNIHDDKFLRDNAFTYLLAQRNTQSLTMTWLFYALFENPKVELKILSELKSIVDESSERKFNDGFALFDSNMIQSAIYLHATLCEALRIYPPVPFEIKDAHKADVLPSGHKVRAGEKILFSPYAMARMKGIWGDDCLEFKPERWITGNGTLKHEPAYKFFAFSAGPRICLGKELSFTQMKMVVATIIYNFHLQMVKGHVVEQSNSILMDMKHGLMVQVRKRSVM
What is the function of this protein?
Cytochrome P450 that catalyzes an intramolecular para-para' C-C phenol coupling of 4'-O-methylnorbelladine in alkaloids biosynthesis, including haemanthamine- and crinamine-type alkaloids, promising anticancer agents.  Catalyzes the formation of (10bR,4aS)-noroxomaritidine and (10bS,4aR)-noroxomaritidine from 4'-O-methylnorbelladine.  Produces also N-demethylnarwedine as a minor product.  Involved in the biosynthesis of haemanthamine.  Can use also 4'-O-methyl-N-methylnorbelladine, (S)- and (R)-coclaurine as substrates, but not 3'-O-methylnorbelladine, 3',4'-O-dimethylnorbelladine, norbelladine, haemanthamine, (10bS,4aR)- or (10bR,4aS)-noroxomaritidine, isovanillin or tyramine.
What are the official names of this protein?
Noroxomaritidine synthase, CYP96T1, Cytochrome P450 96T1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: APOBR_HUMAN
Sequence: MDFLRLYLPGLHQALRGALDSLGTFVSYLLGDAVPTVEREAQAAEELGVVAVGKTGKIVEEEAQEDLEGLRGSQNEGAGRLRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAGETAKAARCQEPSAHLEARKKSKAGSGACQDRSGQAQERQESHEQEVNREERLRSWEQEEEEEEVRAREPGMARGAESEWTWHGETEGKAGAVGPKAAGDNREMEQGVREADAGETEEPGAEGAGKGEEVVVVEKACESTRAWGTWGPGAEPEDWGILGREEARTTPGREEARAILDGEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEEAGIASGGEAGTASGGEEAGTASGGEEAGTASGGDEAWTTSGKEEADLLGVRQTEYGAVPGERLLEATGKVWVLEEEGDEEREAEVSPFPKQPQVLGTERTEEAAESQTAGREAVGGQEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEEAQEERGSSRDPVAELPSDGEAEGTADLEATPEARPEEELTGEESEAAQTSCGLLGVEWGGLTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEASEAFPGAWENRTRKDMERGNTQEDAADGEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEASVSENQELDGSTGADAGPCPSLGEAYARETEDEEAEADRTSRRGWRLQAVAVGLPDREDAQTGSVAAGIMGGDVVPHISAAGAGEALEGVLGQGWDSKEKEEAAAGEHAGGQEFGLEGSAEEEVTGRGSQVEAFESREGGPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWTLLEEEAVGWQEREQREDSEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEPESLEHVRGQEEQPTHQAPAEAAPESVGEAETAEAMGSARGGAANSWSEAPLPGSLLDVSVPRSRVHLSRSSSQRRSRPSFRRTPAWEQQEEPPAPNPPEEELSAPEQRPLQLEEPLEPSPLRHDGTPVPARRRPLGHGFGLAHPGMMQELQARLGRPKPQ
What is the function of this protein?
Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL).  Binds and internalizes TRL when out of the context of the macrophage.  May provide essential lipids to reticuloendothelial cells.  Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP).  Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.
What are the official names of this protein?
Apolipoprotein B receptor, Apolipoprotein B-100 receptor, Apolipoprotein B-48 receptor, Apolipoprotein B48 receptor, apoB-48R.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Binds monocyte-macrophage membrane. Thought to be anchored in the membrane through an interaction with an integral membrane protein.
Protein: SYNEM_MOUSE
Sequence: MLSWRLQTGSEKAELQELNARLYDYVCRVRELERENLLLEEELRSRLSREDRWAEDQALYAEEARSLRQQLDELNWSTALAEGERDALRRELLELQREGVEAGTARSRLDAELGAQRRELEEALGARAALEALLGRLETERRDLDAAHERQVRDLRARAASLTMHFRARATSPAAPPPRLRDVHDSYALLVAESWRESVQLYEDEVRELEQALRRGQESRLQAEDEARLCAQEADALRNQALELEQLRARLEDELLRMREEYGMQAEERQRVIDSLEDEKEALTLAMADRLRDYQELLQVKTGLSLEVATYRALLEGESNPEILIWTENIENVPQEPRNTSYRYTNSVLQRKNEKNLFPRRKTPWAAVNHSSASYSNWPGHLDSQTTTAVGSAARRGLLTSRHSSSATTSGQQKPLEKTISSRANLRPVTPTHGFLRNTDAQMKTLPHRSKVEGTGDTHARRATESVITRESYRGHQGHVAAGAVSSTPSNERTVILGKKLEAQATKEQERDRSGVIRIKPEEKMFDSKEKASEERNLRWEELTKLDRDARKRESRHLRDEAREKEALKERSVKEREVPISLEVSRGSRAEVSTIHLQSPGRKDVSHSGGREAETKETRFRLDTQDTASSLQSDSTTETIAESIVTTILKQFTQSPGAEEEATSFPDTKVTYVDRKEFPGDGKTKTEIVVESKLTDVVDVSDEAGLDYLLSKDVKEVGLKGKSTETMIGEMINLGLKGREGRAKVVNVEIVEEPMSYIGGGKIDFSTPFQVEEVDDVSPSPKGFVEEEDGEGETHMAFSMRPHQTKQPQGTIPHVEEVTEAGDSEGEQSYFVSTPDEYPGGHDREDDGSVYGQIHIEEESTIRYSWQDEIAQGTWRRKMRGDVGGEKPVKVLEVPALSLGGAIGSAHLKEEASGELRAEPTVIEKEIKIPHEFHTSIKGVFSSEPRHQLVEVIGQLEETLPERMKEELSALTRQSQGESGSVSVDVKKVQSAAGGSVTLMAEVNLSQTVDADQLDLEQLSRDEAGEIERAVESVVRESLAKRSSPVPRSPDREDGEEVPAGGILFKRWATRELYSPSGERDDAGQVSPSSDQRVTQGPVSATVEVTSPTGFVQSHVLEDVSQSVRHVKLGPTEMWRTEQVTFGGPTAQVVEVSGDFSEAVSSEGASRSVRHITLGPHQSQVSTEVIFRGSVPTWQETGDTEKPGPVVLSVGADISGSGRMPGSERSHTEKEIRFQGPVSGTAQVGGNFATEESVGSQTFVRSLQLGPKEGFREEIQFIAPIPDKVGWGEEDSEHTKVSLERATSIQRIDIVPQRYLASKQMAPQTLEFRDSEDMVMVEGSAGTIQATHNFTSDREILQNKENTFQRVISGSPPDSVGDTGAEVTANVSRSFRHIQIGPTEEEPSEYFVTGRPVSKTFVLDGSVASPGLVGGADGGSTPCRIALGPKETSFTFQMDLSDTRAIRSWTRDTGSEVEAHGVSHRGGWRIAHSRDERVASTGSGASPGDAHQAPGEKGTEQAGFDKTVQLQRMVDQRSVASDEKKVALLYLDNEEEEEEEGEGWF
What is the function of this protein?
Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton.  It forms heteromeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteromeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells (By similarity).
What are the official names of this protein?
Synemin, Desmuslin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Note=There are at least two distinct SYNM subpopulations, one in which SYMN interacts with DES within the Z- lines, and another in which it interacts with both DTNA and DES at the costamere.
Protein: SELO_RHIL3
Sequence: MTSALQKNRPGAAFPFDNSYVGLPPHFFAAQAPTAVAEPWLIKLNEALAAELGLDVEALRRDGAAIFSGNLVPEGAEPLAMAYAGHQFGGFSPQLGDGRAILLGEVVDRSGKRYDIQLKGAGPTPFSRRGDGRAAIGPVLREYIISEAMFALGIPATRALAAVTTGEPVYREEVLPGAVFTRVAASHIRVGTFQYFAARGDTDGVRALADYVIDRHYPALKEAENPYLALFDAVCERQAALIARWLHVGFIHGVMNTDNMTVSGETIDFGPCAFMDAYDPATVFSSIDQHGRYAYANQPGIGQWNLARLGETLLPLIDAEPDSAVDKANAVIKSYGERFQAHWLAGMLEKIGLAGEEDGDLDLVQALLSLMQAQGADFTLTFRRLSDLAGDDAAEPEFAASFREPDACGAWLTQWRERLSRDPQTASERAIAMRSVNPAFIPRNHRVEQAIEAAVDNGDFSLFEALLSVLSKPYEDQPGFAAYREPPKPSERVLATFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: ECTC_HALED
Sequence: MIVRNLEEARQTDRLVTAENGNWDSTRLSLAEDGGNCSFHITRIFEGTETHIHYKHHFEAVYCIEGEGEVETLADGKIWPIKPGDIYILDQHDEHLLRASKTMHLACVFTPGLTGNEVHREDGSYAPADEADDQKPL
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.  Does not act on N-acetylated amino acids like N-alpha-acetyl-L-asparagine,N-alpha-acetyl-L-ornithine, N-alpha-acetyl-L-lysine and N-epsilon-acetyl-L-lysine.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: RHG15_CHICK
Sequence: MERSTTSDTASEKPNPSHSTGAVQMRIKNANSHHDRLSQSKSMILSDNVKVLEPINRHRRNHSQHNLTLADIISTPDHTVVEKEGYLLKAKIADGGKKLRKNWSTSWIVLTSRKMEFYKESKQPALANLKPGYKPECVDLCGAHIEWTPEKSSRKNVFQITTVSGNEFLLQSDIDFLILDWFHAIKNAIDRLPKERSCTSRNLEFKLRRSSSTELLNSLDTESKESKPEHRKSLIFRLNYSASDSNDRSRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHLVCEHENSTVPQFVRQCIKAVERRGLEVDGIYRVSGNLATIQKLRFVVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYCFFEQFVEAIKIQDNATRIKAVKTLVKKLPRPNYDTMKVLFEHLKKIAAKESVNLMSTQSLGIVFGPTLLRPEKETGNMAVHMLYQNQIVELMLSEYSKIFGSEED
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 15, ArhGAP15, Rho-type GTPase-activating protein 15.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: MIAA_ACISJ
Sequence: MPADHIPALALAGPTASGKTAAAFAIADALAPRLPVEIISVDSALVYRGMDIGTAKPTPAEQARVPHHLIDIRDPLQAYSAAEFVQDATRLIGEIRARGALPLLVGGTMLYFKALFDGIDDMPPADAAVRARLEAQAAAIGWSGMHAELARVDPPTAARLAPGDSQRIQRALEVWHVSGRPLSSFHTTKTVAASDRPMSAASLFSLEPHDRAWLHGRIAERFHAMLAAGFLDEVLRLRARGDLHAELPSMRCVGYRQAWESLDGLYPMSSLPERGIAATRQLAKRQITWLRSMPQRHSIACDAPDATAQLVQAVRARVWGGSA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GCP4_MOUSE
Sequence: MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQYTGHVQQQDHHPPQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLADPHLSISHVNYSLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGTLSAQLEEDEEDLGIGGLTGKQLRELQDLRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKDHKADATQPREVPSRETSPREAPSSGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQRKHLKSNQTDAVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGTLGSFGM
What is the function of this protein?
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
What are the official names of this protein?
Gamma-tubulin complex component 4, GCP-4.
What is the protein family that this protein belongs to?
Belongs to the TUBGCP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: LEU1_BACCQ
Sequence: MKQILFMDTTLRDGEQSPGVNLNEQEKLQIARQLERLGIHVMEAGFAAASEGDFQSVKRIANTIQNATVMSLARAKESDIRRAYEAVKGAVSPRLHVFLATSDIHMKYKLCMSKEDVLDSIHRSVTLGKSLFPTVQFSAEDATRTARDFLAEAVEVAIRAGANVINIPDTVGYTNPEEYYSLFKYLQESVPSYEKAIFSCHCHDDLGMAVANSLAAVEGGALQVEGTINGIGERAGNAALEEVAVALHIRKDFYQAEPSMTLKEIKATSTLVSRLTGMVVPKNKAIVGANAFAHESGIHQDGVLKEVTTYEIIEPELVGESQNLFVLGKHSGRHAFTEKMKELGYEFTTEERDAVFEAFKKLADRKKEITEEDLRALMLGEAAFAAQQYNITQLQVHFVSNSTQCATVVLKDEEGNVFEDAATGSGSIEAIYNAIQRILGLECELADYRIQSITQGQDALAHVHVELKEGTHQVSGFGVAQDVLEASARAYVHAAGKLKSFIQLVK
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: YOSV_BACSU
Sequence: MFKDKNKIIKSVEKINKLEEGLSLFEEGDEEYLSVLVKIQGLYDEISDTALECFKEMTTKIRKTGQKRIIKGIDQLPHTIKENIADQVNDFKGGAI
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YosV.
Protein: MOCOS_DANRE
Sequence: MDTRSLQDFQDLCTFDVFKSFGHYYGYGVDQQALIDQEFKRIKGVTYLDHAGTTLFPESLIKGFHDDISRNVYGNPHSHNSSSRLTHDTVESVRYKILAHFNTSPEDYSVIFTSGCTAALKLVADTFPWKPMSNKEPGSQFCYLTDNHTSVVGIRGATALQGVGTISVSPREVETRARNKTQTNGEEECSTPHLFCYPAQSNFSGRKYSLSYVKGIQSQQLYPACEHHGQWFVLLDAACFVSCSPLDLSQYPADFVPISFYKMFGFPTGLGALLVRNEAAEVLRKTYFGGGTAAAYLVEENYFIPKPNLASRFEDGTISFLDIISLHHGFETLQKLTGSMTNIQLHTFGLARYTYTVLSCLCHSNGKHVAQIYCDNDFQSIAEQGAIINFSLLDCHGRTVGYSQVDKMASLFNIHIRTGCFCNTGACQHYLAISNQNVKSNLHAGHICGDNIDLVDGRPTGSLRVSFGYMSSFEDCQNFLRFVVNCFVDKPLILDQTKLAKLNSAAPIEPSSSYSPSPDRMAVSEVTMSKDGKKDGSSCTLTNLFIFPVKSCASFEVTEWPLGPQGLLYDRLWMVVNENGVCLSQKREPKLCLIQPVVCLAANTLKLQISGSEAITVPLDPSLEKSDLRTSQSKVCGDRVQTVDCGEEVSAWLSEFLGKPCRLIRQRPEFLRDMKFGQGDCCPTPLSLVNEAQFLLINRASVCFLQEAIANRYNSDNEETWRDTEQLVQRFRANLVISAQEPFAEDNWSHLTIGNTQFQVIGKCGRCQMIGVDQKTATRTQEPLRSLSECRSGKVTFGVYLAHQSARNSTHPVLSIGSHVIPKISDSTDKF
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase, MCS, MOS, MoCo sulfurase, Molybdenum cofactor sulfurtransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Protein: YCF3_HORVU
Sequence: MPRSRVNGNFIDKTFSIIANILLRIIPTTSGEKKAFTYYRDGMLAQSEGNYAEALQNYYEATRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAILEGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAQNWLKITKRFEFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HISZ_LISMC
Sequence: MNLNKNLPTGTRDKLFREAQAAYKIEQQVNHYFEKRGFKRIETPVIEFEDVFSSEHQADAKLYRFFDEKGRLTVLRPDMTLPIGRVVSTTGVMLPLKLSYSGKIFRANEDFGGEQNEQTQAGIEIIGYPSIKAEIECILSGIGVLNALEIPNFQIELGHAAIYRRVIQLLNLSETAEIDFRQLIQNKSLTGIKRFVANNPSTLDDFILAIPRLFGPATAILNQAKSLTTDKGILTALREMETIVEAVSYTADISVDLGLVQDFHYYTGIIFRGYADLAADNFLSGGRYDHLLEQFTSSSSPAVGLALNLDSLTTLQNRAGIIKKQTPTTLLIHYDLEALPQAEKFMQETPNSELSFFETASNAISFAKKWHIPEVVHVSSQGIQTIFQREVD
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_LEUMM
Sequence: MSYAADVKKELTGLIVHAGNAKAELAALMRMNGVSTLGFDQTIRVQTENAAIARRIYTLLKETYVEVEVEVSVTDHNHLSQHKSYGVLLKTKIDEVLDDLGIDPFGLHPEVPPRMLNQVDKRRSFLRGAFLAAGSVNSPERANYHLEIYTTHEELAEQLMIMMQEFDLPSKISERGNGFIVYLKRAEKIVDFLQTIGATQSMLKFEDIRMMRDMRNSVNRLVNAETANMQKTAIAANKQVSQINLIIDTLGSLDILPKKLRDIAKARLEYPDETLAELGEVLDISKSGANHRMRKLTQLATMIEQGIDYDLTKL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: SUCC_METJA
Sequence: MKLHEYEAKNIFKKYGIPVPESFLVSKEDDLNSINVDKEVVLKAQVLVGGRGKAGGILFASNKEEFIKKAEELFNKEVKGEKVEKILVEEKLPIEKEYYVSIIIDRDAKKPLIIFSTEGGVDIEEVAEKNPEKIIKYHIDVRKPFLPYIARWIVKEAKLPSNEIGKVADVIYKLYKIFKELDATMVEINPLVITKDGNVYAADAVLHLDDDAAFRHNYEEFEEYKNKEKLPFAYVELDGDVAVIGNGAGLTLASMDIINNLGRKPACFLDIGGGADAETVKLALRKVLENKNVKGIFINILGGITRCDEVAKGIVEVLKEHPNVKFAVRMMGTNEEIGRKILEEHGIPYETSMEEAGRKLIEQL
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.