PharMolix/UniProtQA huggingface dataset:
Protein: TGL_BACSU
Sequence: MIIVSGQLLRPQDIENWQIDQDLNPLLKEMIETPVQFDYHSIAELMFELKLRMNIVAAAKTLHKSGAKFATFLKTYGNTTYWRVSPEGALELKYRMPPSKAIRDIAENGPFYAFECATAIVIIYYLALIDTIGEDKFNASFDRIILYDWHYEKLPIYTETGHHFFLGDCLYFKNPEFDPQKAQWRGENVILLGEDKYFAHGLGILNGKQIIDKLNSFRKKGALQSAYLLSQATRLDVPSLFRIVR
What is the function of this protein?
Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links.  In wild-type spores at 37 degrees Celsius, tgl mediates the cross-linking of GerQ in higher molecular mass forms, probably in cooperation with YabG.
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase, Transglutaminase, TGase.
What is the protein family that this protein belongs to?
Belongs to the bacillus TGase family.
Protein: COTH1_RHIO9
Sequence: MKSLLFVVFIFLTTTYAAKVSFKVIAPDAKNRVHVNINGVLVELKASDPDVPYYTGFAELKHGQSYNYVVDGNAEPFKRLLNGSSTKNEFFNRPVTYATNIPELPSILTEGSWTRGDTSNPIWDSNYVPSIFVTGNPREMNELIENVKKNTYKTKITFIGPETINTFEGCTLGLHKPGRKHNDAKQSWIWALPEGQFMANRNWFKIRHMEEDPTQLREKLYADILRKMGTYANEANMVRFFINKEGMGIFNMLDDVIMYSYINAMFYHGDTPEQLGGLYDGASGASFNFPGDFDSFIPNVESPLDQDAIEPFSKAFTSIDFLEDEQVKTIGKYFDYDQFLRFMVMEFLTGDWDGYWQEQTNDGAYIDINDHNKIYYLGQDFDATFGVNLEQKREFVNVSYTEYPKLFPGGVLINRLLQNPGVKKTFENYLKITVQEIFNNATLGPYVTARHEFLAPDLQWDRSIKQRSPGNIFGWTFEQTYENLFEGVTAPGKNSGGADWGLLEWVAAKEKAVKSYLSSSEAADAATVTQVPEAPGTDGTPSESTAWPHANTRFRQAEASNTHKIGTSSPSNFIVKIKQGTVSSSSSIKRTPCILPLVILASTLFASFF
What is the function of this protein?
May play a role in cell adhesion.
What are the official names of this protein?
Spore coat protein homolog 1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: FTSB_SHESR
Sequence: MKFFVIALIVLLGLLQYRLWSGDNSLPEYFVLQKQIAAQQEGNAKLNERNQVLKEEIIDLKSGTEAIEERARNELGMVKEGETFYRVVGGDRSVSSPSQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: ZNUC_VIBPA
Sequence: MSSLVSLEQLCVEFDDRRVLDNISMELEKGKITTLIGPNGAGKSTLVKVILGLQKPTSGKLVKAKKLKIGYVPQKLKLNDSLPLNVIRFLNLAGKYSKQECLDALRLVGAEHLIKSNMHRLSGGENQRVLLARALLQRPDLLVLDEPAQGVDVQGQIDLYDLIESIRHRFDCAVFMVSHDLHLVMAKTDDVICLHHHVCCSGSPATITQHPSYIALFGNAARESLAFYHHDHEHHHHDLSGSPVSGDATSCSNHNHGHHHHD
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NDK_CAMJD
Sequence: MEKTLSIIKPDAVKKGVIGKILDRFESNGLRIAAMKKVQLSKEQAENFYAVHKERPFFKDLVEFMISGPVVVSVLEGEGAVLKNRDLMGATNPKEAKAGTIRADFAESIDANAVHGSDSLENAKIEIEFFFKPNEIY
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL39_SULIY
Sequence: MSRNKPVAKKFRLAKALKANSPIPIWIVLKTRGRVRYNPLRRNWRRNDLKV
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: ATPA1_LISMO
Sequence: MKTIHFDMNKYETHVDLEYLKEHGRVEKISDGVIFCSGLENAALHQAVLIDERHRGVILELNEEFVGIGLIDKTNDILEGMHVGVSGKFIEVDLFEEMAGRIIDTTGKMLYEESEEKPTATSPLFCVTPAIMTIDSVTRPLNTGLAVIDSITPIGRGQRQLILGNRQSGKTQIAVDTIINQHDQNVHCIYVAIGLKAAYIAEVIETLRNHGAMEYSTVVATAASDSLTAQYLTPYAGMALAEALRDQGKDVLIILDDLTKHADAYRAITLLFNRPPGREAYPGDSFYIHSSLLERAVQMNEEHGGGSITAIPMIETLSDDVTAYIPTNVISITDGQLFLKSDLFNRGQKPAVDVGVSVSRIGGDAQHPIIRKLSKNLTLILSQFEELKELLDFGNALDDGSMKMVSDGRLLTELFKQKILSPLSVTELIVILYAFQNGFLTKIPPANIQTFKGLLLEKAHMHKDFESFSAQIEAINELNESHVEMLEEIIRETGRLFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 1, ATP synthase F1 sector subunit alpha 1, F-ATPase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEUD_SHEFN
Sequence: MQAFTAHTGLAVAIDSANVDTDQIIPKQFLSKVTRDGFGVHLFHDWRYLDDAGDKPNPDFELNQPRYKGASILLAQENFGCGSSREHAPWALADFGFRVIIAPTFADIFYGNSINNGLLPVKLTSVQVQQLMDEVAAKEGAQITVDLQALTVTSPSGSVFDFTIVESARHKLLNGLDAIGLTLSFEQQISDYETHIPAWFA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RHBL4_MOUSE
Sequence: MQRRTRGINTGLLLLLSQVFQIGINNIPPVTLATLAVNVWFFLNPWKPLYHSCISVEKCYQQKDWQRLLLSPLHHGDDWHLYFNMVSMLWKGVKLERRLGSRWFAYVIATFSLLTGVVYLLLQFTVAELLNQPDFKRNCAVGFSGVLFALKVLSNHYCPGGFVNILGFPVPNRFACWAELVAIHFCTPGTSFAGHLAGILVGLMYTQGPLKKIMDTCAGIFISHAGPSGQQNHFNNAGPSGYQNHYADGRPVTYDATYRNYDVYTAGLSEEEQLERALRASIWDRGNTRNGPMPYGFRLPPEEMRRQRLHRFDGQ
What is the function of this protein?
Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions.  Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.  Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins.  Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins.  Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner.  Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing.  Involved in the regulation of exosomal secretion; inhibits the TSAP6-mediated secretion pathway.  Involved in the regulation of apoptosis; modulates BIK-mediated apoptotic activity.  Also plays a role in the regulation of spermatogenesis; inhibits apoptotic activity in spermatogonia.
What are the official names of this protein?
Rhomboid-related protein 4, RRP4, Rhomboid domain-containing protein 1, mRHBDD1, Rhomboid-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein.
Protein: FOLD_RHOP2
Sequence: MTATIIDGKIISAELRARVAAEVTRIKADHGITPGLAVVLVGSDPASEVYVRSKHKQTQEAGMASFEHRLPADVPQAELLALIGQLNADPAVHGILVQLPLPKGLDSNAVIDAIDPAKDVDGLNPVNAGRLASGLFALTPCTPLGCIIMAKQVHASLEGMNAIVIGRSNLVGKPLVQLLLNENATVTIAHSRSRDLPALCRQADLVFAAVGRPEMVKGDWIKPGATVIDVGINRTPSPDGGKDKLVGDVAFAEAKDIAGAITPVPGGVGLMTVACLLVNTVRAASAIHGLPKPAV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ADPP_MYCTU
Sequence: MAEHDFETISSETLHTGAIFALRRDQVRMPGGGIVTREVVEHFGAVAIVAMDDNGNIPMVYQYRHTYGRRLWELPAGLLDVAGEPPHLTAARELREEVGLQASTWQVLVDLDTAPGFSDESVRVYLATGLREVGRPEAHHEEADMTMGWYPIAEAARRVLRGEIVNSIAIAGVLAVHAVTTGFAQPRPLDTEWIDRPTAFAARRAER
What is the function of this protein?
Catalyzes the hydrolysis of ADP-ribose (ADPR) to AMP and ribose-5-phosphate.  Can also hydrolyze ADP-mannose and ADP-glucose, with lower efficiency.  Has weaker activity with NAD, GDP-sugars and UDP-sugars (PubMed:27683242).  Also catalyzes the conversion of 8-oxo-dGDP to 8-oxo-dGMP, and 8-oxo-GDP to 8-oxo-GMP.  Functions in concert with MutT1 to detoxify 8-oxo-dGTP to 8-oxo-dGMP and may play an important role in supporting cellular growth under oxidative stress (PubMed:23463507).  The catalytic efficiency is much higher for the hydrolysis of ADPR than 8-oxo-dGTP, suggesting a more relevant biological role in hydrolysis of ADPR (PubMed:27683242).
What are the official names of this protein?
ADP-ribose pyrophosphatase, 8-oxo-(d)GDP phosphatase, ADPR hydrolase, MT-ADPRase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: PGP_SULTO
Sequence: MVLSDFDRTLSDEKDNFIIKQEVVEVVNKFSAKFLFFVVTGRERKYMDILAKGLFPTGWIIENGGIIILRDKEIKLVDEKWYKIRKNLAKILDKNGIKYSLGEVIIYVNSAIDYKDKLDKINEAKIEWNRSDAMIMPKNVSKGEAVKILKSILNFEGVTIAIGDSQNDISLFSVADIKVAVANALPEIKAISDIVLDKEDGIGVMRFLEKILNDGSYLEKLIGFRK
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: SPN1_HUMAN
Sequence: MEELSQALASSFSVSQDLNSTAAPHPRLSQYKSKYSSLEQSERRRRLLELQKSKRLDYVNHARRLAEDDWTGMESEEENKKDDEEMDIDTVKKLPKHYANQLMLSEWLIDVPSDLGQEWIVVVCPVGKRALIVASRGSTSAYTKSGYCVNRFSSLLPGGNRRNSTAKDYTILDCIYNEVNQTYYVLDVMCWRGHPFYDCQTDFRFYWMHSKLPEEEGLGEKTKLNPFKFVGLKNFPCTPESLCDVLSMDFPFEVDGLLFYHKQTHYSPGSTPLVGWLRPYMVSDVLGVAVPAGPLTTKPDYAGHQLQQIMEHKKSQKEGMKEKLTHKASENGHYELEHLSTPKLKGSSHSPDHPGCLMEN
What is the function of this protein?
Functions as an U snRNP-specific nuclear import adapter.  Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs.  Binds specifically to the terminal m3G-cap U snRNAs.
What are the official names of this protein?
Snurportin-1, RNA U transporter 1.
What is the protein family that this protein belongs to?
Belongs to the snurportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling protein. Its nuclear import involves the nucleocytoplasmic transport receptor importin beta (PubMed:10209022, PubMed:12095920). It is re-exported to the cytoplasm by the XPO1- dependent nuclear export receptor pathway (PubMed:10209022).
Protein: BR2EG_PELRI
Sequence: GIMDTLKNLAKTAGKGALQSLLNHASCKLSGQC
What is the function of this protein?
Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.
What are the official names of this protein?
Brevinin-2Eg.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPL_AROAE
Sequence: MENVLGFVALAAGLIIGLGAIGACIGIGIMGSKYLEASARQPELMNALQTKMFLLAGLIDAAFLIGVGIAMMFAFANPFQLV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KATG_ERYLH
Sequence: MQMDAKTGDISGGCPFHGDGGTRSLLGRTNRDWWPDQLQLEILKEGGRNPDPMGEDFDYVEAFNAIDYTALKQDLTDLMTDSQEWWPADYGHYGPFFIRMAWHAAGTYRTGDGRGGSSSGQQRFAPLNSWPDNGNLDKARRLLWPIKQKYGKHISWADLFILTGNVAIESMGGPVFGFGGGRKDVYEPEMVYWGTEEQWVDTGAETRIHPDEGRALENPLAAIQMGLIYVNPEGPGGDPHDPEGMARDMRETFARMAMNDEETVALTAGGHAFGKCHGAKPADTFGTAPEGENLHLMGMGWLTDEEEIRNGHVTTSGIEGPWTPNPTQWGNDYFRLLFKYEYELTQSPAGAYQWTPVDPEEADMAPDARDPSKKVPTIMTTADMALKRDPDYRKISERFRDDQAALDDAFARAWFKLCHRDMGPKVRYQGPEVPSEDLIWQDPVPSGTAPSDSDVSSFKSAVLDSGLTVSELVKAAWASASTYRNSDHRGGANGARVRLAPQKDWAANDPEELGKVLSKLDELRGNLSMADAIVLAGSAAIEKAARDAGHSVSVDVTTGRGDATDEHTDAESFEPLEPFADGFRNYLKTKASVKTEEMLIDKAHLLGLSIPEMTALVGGMRALGAVSRHADHGDRIGVLTDRPGQLTNDFFVNLLDMGTKWEVVDESGDEEFVGKDRKSGDEKWRATRTDLVFGSNSQLRAQAEVFAESGNEQLFLDTFVKAWTKVMDADRFDVTYAKYN
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: NTRXL_RICBR
Sequence: MSLIDVLIVDDEEDIRNIIAAILKDEGFNPKVAANSTQALKILAEKPVSAVILDIWLQGSEMDGLGILEVIKKRYPLMPVIIISGHGTIETAVNAIKMGAYDYIEKPFNNDKLVILLKRACEVTKLKRENIDLKSKVIDKTELVGNSTITLKYKAEIDKAASSSSRIMIHGKVGSGKELTARLIHKKSKRVNNLFIIFSPTCMTLEKINQELFGEAEKQESNNNSNKRPTILEFANNGTLYIDEVSNIPVPIQIKLLKFLKDHTIKKPCGKIVKVDIKIITGTSKNIQEEVNNGRFLEDLYYRLNVSSLKVPSLFERKEDIPLLVKYFVKQLSKFSGLKERVFADETIAALQSYEWPGNIRQLRNVVEWTLIMNPITSGNNEIIKPYMIPSEILANSVNLTKLEDSFDMLSMPLREAREVFERQYLSAQMSRFNNNILKTSSFVGMERSALHRKLKLLSLHIPPTGRINEEEYEEANA
What is the function of this protein?
Member of the two-component regulatory system RBE_0312/RBE_0470.
What are the official names of this protein?
Putative response regulator NtrX-like.
Protein: UVRB_SALTI
Sequence: MSKPFKLNSAFKPSGDQPDAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMLIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQVESTVPRYTIYPKTHYVTPRERILQAMEEIKDELADRRKVLLANNKLLEEQRLSQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGDEVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGKGKGRSTAKAGIVELDMTPKALQQKIHELEEQMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP19A_COTJA
Sequence: MIPETLNPLNYYTSLVPDLIPAATVPIIILICVLFLIWNHEGTSSIPGPGYCMGIGPLISHGRFLWMGVGNACNYYNKTYGEFVRVWFSGEETFIISYFDAWQALLLKPDIFFKISWLCKKYEEAAKDLKGAMEILIEQKRQKLSTVEKLDEHMDFASQLIFAQNRGDLTAENVNQCVLEMMIAAPDTLSVTLFIMLILIAEHPTVEEKMMREIETVMGDRDVQSDDMPNLKIVENFIYESMRYQPVVDLIMRKALQDDVIDGYPVKKGTNIILNIGRMHKLEFFPKPNEFSLENFEKNVPSRYFQPFGFGPRGCVGKFIAMVMMKA
What is the function of this protein?
Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
What are the official names of this protein?
Aromatase, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: RL6_MYCCT
Sequence: MSRIGNRLLQIPNGVEVKIAENNLVTITGSKGTLSKQFSPLIKIEVEENKLITKRLNEQKHTKQLHGTTNSLLQGMLTGVSEGFKKELQITGVGYKAAVNGSKLNLSLGYSHPVEFEIPDGVVIQAVKPTELAITGIDKQLVGQVAANIRAYRKPEPYKGKGIKYKNETIIRKEGKAAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CLS_STAAM
Sequence: MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANSIWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDKEDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQYYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVIDGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIASSGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAGVKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYAKRSLWIKFKEGISQLLSPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL25_ANADE
Sequence: MAENVLSAQKRTEQGKGPARRLRQQGLIPAVVYGGKREPTHVALDPATLLKAIETPHKFNTLLELQVEGASKHVLFKDYTVDPVTRKLLHADFLEVSMDQPVKVNVPVVTVGRAAGVAEGGILSVAAHAIVVEALPNKIPVRIEVDVTELKIGRSLHVSELKAPEGCKFKFQTDYVVVFVAVPEKEEVAAPVAAAVPGAAPAEGAAPAAGAAAPAAGAAPAAGAAPAKGGEAKGGDKGKK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ANMK_YERPE
Sequence: MKSGRFIGVMSGTSLDGVDVVLAAIDERMVAQQASYTHPIPLQLKKDILGMCQGQSTTLSAVGKLDAQLGILFAEAVLALLAKEGLSAQDITAIGCHGQTVWHEPLGEPAFTMQLGDNNRIAAMTQIATVGDFRRRDMAYGGQGAPLVPAFHHALLAHATEKRMVLNIGGIANLSVLLPDSPIRGFDTGPGNMLMDAWIWRNCSLPYDKDACWALSGHVNQPLLEQMFNDPYFRLPAPKSTGREYFNAAWLDKQLARIPGVTAEDIQATLAELTAVSITEQVRLAGGCDRLLVCGGGARNPLVMARISALLSGTEVCTTDDAGIRGDDMEALAFAWLAFRTLSGKPGNLPSVTGASRETILGAVHPVSSW
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: B2CL2_HUMAN
Sequence: MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
What is the function of this protein?
Promotes cell survival.  Blocks dexamethasone-induced apoptosis.  Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
What are the official names of this protein?
Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-W.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Peripheral membrane protein. Note=Loosely associated with the mitochondrial membrane in healthy cells. During apoptosis, tightly bound to the membrane.
Protein: DEOD2_VIBVY
Sequence: MATPHINAQPGDFAETVLMPGDPLRAKYIAETFLEDVKQVCDVRNMFGFTGTYKGKKVSVMGHGMGIPSACIYVHELIAEYGVKNVIRVGSCGAVRDDVNLMDVVIGMGASTDSKVNRIRFNDHDFAALADYGLLEEAVKQARAQNVPVKVGNVFSADLFYTPEADIFEKMEKLGILGVDMEAAGIYGVAADLKAKALTILTVSDHIIRGEKLSSEDRQKSFNDMMKVALETAINL
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type 2, PNP 2.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: ATPB_FERIS
Sequence: MSKKSVGKIVRIIGPVVDVKFQEGDLPDIYDALVVINPQTGKKLILEVEQLIGDNIVRTVAMDSTDGLVRGLEVENTGEPIKAPVGRGVLGRMFNVIGEPIDEQGELKDIEYWPIHRPAPSMTEQKTEIEILETGLKVIDLLAPFPKGGKIGFFGGAGVGKTVLVMEMIRNIAIEHHGFSIFAGVGERTREGNDLYLEMTEAGVLNNTVLVFGQMNEPPGARFRVALTALTIAEYFRDVEGRDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTDMGELQERITSTKKGSITSVQAIYVPADDITDPAPATTFTHLDATIVLSRQLAALGLYPAVDPLDSTSKILDPNIVGKEHYEVARGVQEVLQRYKDLQDIIAILGMEELSEEDKLIVQRARKIQRFLTQPTHVAERFSGIPGVYVPIKETIRGFKEILEGRYDDLPEAAFYMVGTIDEAVEKAKKLMKSAVI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: THIE_NEIMA
Sequence: MTFLPLKSPLKFYAVVPTADWVERMVEAGADTVQLRCKALHGDELKREIARCVAACQGSHTQLFINDHWREAIEAGAYGVHLGQEDMDTADLAAIAAAGLRLGLSTHSVAELDRALSVHPSYIASGAIFPTTTKQMPTAPQGLDKLREYVKQAGGTPVVAIGGIDLNNARAVLATGVSSLAAVRAVTKAANPEAVVKAFQALWDG
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: CSHA_BACHK
Sequence: MTTFRELGLSDSLLQSVESMGFEEATPIQAETIPHALQGKDIIGQAQTGTGKTAAFGLPLLDKVDTHKESVQGIVIAPTRELAIQVGEELYKIGKHKRVRILPIYGGQDINRQIRALKKHPHIIVGTPGRILDHINRKTLRLQNVETVVLDEADEMLNMGFIEDIEAILTDVPETHQTLLFSATMPDPIRRIAERFMTEPQHIKVKAKEVTMPNIQQFYLEVQEKKKFDVLTRLLDIQSPELAIVFGRTKRRVDELSEALNLRGYAAEGIHGDLTQAKRMSVLRKFKEGSIEVLVATDVAARGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGKKGIAMLFVTPRESGQLKNIERTTKRKMDRMDAPTLDEALEGQQRLIAEKLQSTIENENLAYYKRIAEEMLEENDSVTVVAAALKMMTKEPDTTPIALTSEPPVVSRGGGSKKRGGNGGGYRDGNRNRSRDGRGGDGRNRDRNRDGRNRDGNRDRNREGSRDGNRGRRGEGQGRPGSSNGRGERKHHSRKPQA
What is the function of this protein?
DEAD-box RNA helicase possibly involved in RNA degradation.  Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase CshA.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. CshA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.