PharMolix/UniProtQA huggingface dataset:
Protein: EPM2A_CANLF
Sequence: MRFRFGVVVPPAGAGAAPELLVVGSRPELGRWEPRGAVRLRPAGSAAGGGARALQEPGLWLGEVELAPGEAARDGAEPARVDTFWYKFLKREPGGALSWEGNGPHHDRCCTYNENNLVDGVYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHITIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYKEEGLVYIWMPTPDMSTEGRVQMLPQAVCLLHALLENGHTVYVHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKRPAVYIDEDALARAEEDFFQKFGKVRSSVCSV
What is the function of this protein?
Plays an important role in preventing glycogen hyperphosphorylation and the formation of insoluble aggregates, via its activity as glycogen phosphatase, and by promoting the ubiquitination of proteins involved in glycogen metabolism via its interaction with the E3 ubiquitin ligase NHLRC1/malin.  Dephosphorylates phosphotyrosine and synthetic substrates, such as para-nitrophenylphosphate (pNPP), and has low activity with phosphoserine and phosphothreonine substrates (in vitro).  Has also been shown to dephosphorylate MAPT.  Shows strong phosphatase activity towards complex carbohydrates in vitro, avoiding glycogen hyperphosphorylation which is associated with reduced branching and formation of insoluble aggregates.  Forms a complex with NHLRC1/malin and HSP70, which suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS).  Acts as a scaffold protein to facilitate PPP1R3C/PTG ubiquitination by NHLRC1/malin.  Also promotes proteasome-independent protein degradation through the macroautophagy pathway.
What are the official names of this protein?
Laforin, Glucan phosphatase, Lafora PTPase, LAFPTPase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane. Note=Colocalizes with glycogen synthase in punctate structures in the cytoplasm. Primarily associated with polyribosomes at the rough endoplasmic reticulum, and also detected at the plasma membrane. Under glycogenolytic conditions localizes to the nucleus.
Protein: AN33B_HUMAN
Sequence: MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT
What are the official names of this protein?
Ankyrin repeat domain-containing protein 33B.
Protein: INHBA_PIG
Sequence: MPLLWLRGFLLASCWIIVRSSPTPGSGGHSAAPDCPSCALATLPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVELEDDIGRRAEMNELMEQTSEIITFAEAGTARKTLRFEISKEGSDLSVVERAEIWLFLKVPKANRTRTKVSIRLFQQQRRPQGSADAGEEAEDVGFPEEKSEVLISEKVVDARKSTWHIFPVSSSIQRLLDQGKSALDIRTACEQCHETGASLVLLGKKKKKEEEAEGRKRDGEGAGVDEEKEQSHRPFLMLQARQSEEHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
What is the function of this protein?
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.  Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.  Inhibins appear to oppose the functions of activins.
What are the official names of this protein?
Inhibin beta A chain, Activin beta-A chain.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCSH_BURCJ
Sequence: MSNVPAELKYTDEHEWIRTEADGTLTVGITDHAQSTLGDIVFLELPEVGKSVNAGDAVGVVESVKAASDIYSPVSGEIVAINEAATDAPEEVNGDAYGVWLFKIKLAAGASTDKLIDADAYSKLID
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: DEOD_ECOLU
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: VSP3_CRODO
Sequence: WDKDIMLIRLNKPVSYSEHIAPLSLPSSPPIVGSVCRPHCANINLLDYEVCRTAHPQFRLPATSRILCAGVLEGGIDTCHR
What is the function of this protein?
Thrombin-like snake venom serine protease.
What are the official names of this protein?
Thrombin-like enzyme collinein-3, SVTLE collinein-3, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_GLOSR
Sequence: MTNIRKTHPLLKIVNSSFVDLPAPSSLSSWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLFPFIVAALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSALVLFSPDLLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIVPMLHTSKQRSMMFRPLSQCLFWFLVAILFTLTWIGGQPVEYPYIIIGQMASVLYFLTILVFMPLVSIMENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GATB_CHLL2
Sequence: MKYELVVGLEVHCQLNTNSKAFCGCSTRFGNPANTNVCPVCLALPGALPVLNRRVVEDAVKLGLATGCSIAPSSILARKNYFYPDLPKGYQISQFEEPICTEGMLRIDVGDGCRDIRLIRIHIEEDAGKSIHDIGDDTYIDVNRCGVPLLEIVSYPDIRTSREASAYLQKMRQIVKYLGISDGNMEEGSLRCDANVSVRLFGAEEYGTRTEIKNMNSFKNVEKAIEYEMQRHIDIIDGGGTIVQETRLWDADKGETRSMRGKEFAHDYRYFPDPDLVPVLVDQEMLERIRLELPEFPEDRERRFVSEYGIPPYDAGVLTVEREIADYFERTLTVCGDAKAASNWVMGEVMRTLKEKYLDIKEFAISPERLGGLIGLIGKGAISNTIAKQVFELMQTGEASAEEIVDREGLAQVSDTGAIERTVDEILEANPKQLADYREGKTKLFGFFVGQCMARMKGKANPQVVNDVLKSRLDG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: Y2971_MYCTU
Sequence: MTGESGAAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVGRAIAASGVAREELFVTTKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWPAPPVGKYVDAWGGMIQSRGEGHARSIGVSNFTAENIENLIDLTFVTPAVNQIELHPLLNQDELRKANAQHTVVTQSYCPLALGRLLDNPTVTSIASEYVKTPAQVLLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLNDGTRVREDPLTYAGT
What are the official names of this protein?
Uncharacterized oxidoreductase Rv2971.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: CH10_BRUSI
Sequence: MADIKFRPLHDRVVVRRVESEAKTAGGIIIPDTAKEKPQEGEVVAAGAGARDEAGKLVPLDVKAGDRVLFGKWSGTEVKIGGEDLLIMKESDILGIVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_ACIAD
Sequence: MGNIPLEHGLIVATILFALGFYGVMVRRNLLFMLMSLEIMMNAAALAFVLAGSVWAQPDGQIMFILILTLAAAEACIGLAIVLQFYHRFHHLDVDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HUTU_HAHCH
Sequence: MKDPRHDDQREIRAPRGSELNAKSWLTEAPLRMLMNNLDPEVAEHPKSLVVYGGIGRAARDWECFDKIVEVLKRLEDDETLLVQSGKPVGVFKTHADAPRVLIANSNLVPHWANWEHFNELDKKGLMMYGQMTAGSWIYIGSQGIVQGTYETFVSVAKQHFNGEAHGRWILTGGLGGMGGAQPLAATMAGFCMLAVDCDPSRIEFRLRTRYLDKQAKDLDDALAMIENAKKTGEAISIGLLGNAADVYAELVKRGVTPDVVTDQTSAHDPLNGYLPQGWTMEHAAEMRLKDPAAVVKAAKQSMAVQVQAMLALQEAGAATLDYGNNIRQMALEEGVKNAFDFPGFVPAYIRPLFCEGVGPFRWAALSGDPEDIYKTDAKVKELIPDNPHLHNWLDMARERISFQGLPARICWVGLKDRARLGLAFNEMVRNGELKAPVVIGRDHLDSGSVASPNRETESMMDGSDAVSDWPLLNAMLNVAGGATWVSLHHGGGVGMGFSQHSGVVIVCDGSEAADQRIARVLRNDPGTGVMRHADAGYDIARNCAKENGLDLPMLKD
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLL5_CHICK
Sequence: MQILTLLFAVLLLMLRAEPGLSLARGLPQDCERRGGFCSHKSCPPGIGRIGLCSKEDFCCRSRWYS
What is the function of this protein?
Has bactericidal activity.
What are the official names of this protein?
Gallinacin-5, Gal-5, Beta-defensin 5, Gallinacin-9, Gal-9.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule.
Protein: RECO_LACDA
Sequence: MAADLLDVHGLLFKRQQYKEADLLAKLWTKELGIVTVIAKGGMRPKSQLAAAVLPFTEGTFGILTRYKGISQLRTYKKLSQHDELFTDLDKNAYLSYLFDLADHAFSEYQKLGGYYDLLLVAFNRIVAGQDPEIIAQIVQLQLLDAFGVAPQLGACVICGKEKGIFDYSIAAGGVVCSDHFRSVSRLHLSPKATALIRTLALLPISRLGEIQIGEDLKKESRRAIAQIYQATVDLHLPSLRFLNEVRGS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PTH_TOLAT
Sequence: MTQPIQLIVGLGNPGPEYANTRHNAGAWYVASLAERYNGSLREDPKYFGLTGRIQINGQDVRLLIPTTFMNLSGKSVVALAKFFQIPPESILVAHDELDLPPGVAKFKQGGGHGGHNGLKDIINKLGNNNQFHRLRLGIGHPGTKEQVVGFVLTKAPKAEQQLIDDALDEAVRATDILFTNDMTKAMNRLHSFKATA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_SHEAM
Sequence: MKLQLIAVGTKMPDWVTRGFEEYQRRFPRDMALELVEIPAGKRGKNADIARILQKEGEQMLAAIPKGNHIVTLDLPGKNWTTPELASALSKWQLDGRDVSLLIGGPEGLAPACKQAAAQSWCLSALTLPHPLVRVVVAESLYRAWSINNNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_XANOM
Sequence: MRPAQASIDLEALRHNYRLAKRLGGSKALAVVKADAYGHGAVPCAQALEPEADGFAVACIEEALELRQAGIRAPILLLEGFFEHDELRLIAEHDLWTVAATPQQVRALAAFQSPRPLRVWLKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLARADELDCSRTDEQAVAFALTAGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQDTENTAQLRPVMTLRSRIILVRDLPVGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQVCPLIGRVSMDMLTVDLTDHPQADIGATVQLWGQAPRVGPLATQCNVSAYQLLCGLKRVPRTYVASAAVGEVAAR
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: ATPE_CLOAB
Sequence: MANNIKLSILTPQKTFYVGDVKEIITRTVEGEIGILPNHTDLVAFLTPTETILVEEDGSRKKVFTSTGILNVGESEVSFMCDASEWPDEIDIQRAETAKERAEKRLKTSNNIDVKRAELSLSRALARIKTKND
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ZUPT_ECOSE
Sequence: MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
What is the function of this protein?
Mediates zinc uptake.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSL8_ARATH
Sequence: MDFRNSFKSHSSYKQIRSPGDQSEPSPEHLPILHDHHPDHSGMVVDDQKPDSTRSSLDDGRNAPVERDASYKFWQDNTTGTSTDHTAVRTSDKDPIAISRKGDRLSGSFDFVHGKLPVDESPTKMVAGEPVNRQWRGRNNEEITLDVDQENDDVSHQTMPTPTSTARTSFDASREMRVSFNVRRAGGAFVAGSVPSSSSHSSSSSSATMRTNQDQPQLQEEEVVRCTSNMSFQRKSELISRVKTRSRLQDPPREEETPYSGWRSGQLKSGLLADIDEEDDPLAEEDVPDEYKRGKLDAITLLQWLSLVAIIAALACSLSIQSWKKVRVWNLHLWKWEVFLLVLICGRLVSGWGIRIVVFFIERNFLLRKRVLYFVYGVRRAVQNCLWLGLVLLAWHFLFDKKVQRETRSRFLPYVTKILVCFLLSTILWLIKTLVVKVLASSFHVSTYFDRIQEALFNQYVIETLSGPPMIEMSRIEEEEERAQDEIFKMQNAGANLPPDLCAAAFPPGKSGRVMNPKLSPIIPKSTTDNGISMEHLHRMNHKNISAWNMKRLMKIVRNVSLTTLDEQMLESTYEDESTRQIRSEKEAKAAARKIFKNVEQRGAKYIYLEDLMRFLREDEAMKTMGLFEGAPENKRISKSALKNWLVNAFRERRALALTLNDTKTAVNKLHHMINIVTAIVIVVIWLVLLEIASSKVLLFVSSQVVLLAFIFGNTVKTVFESIIFLFIVHPYDVGDRCEIDSVQLVVEEMNILTTVFLRYDNLKIMYPNSLLWQKSINNYYRSPDMGDAIEFCVHITTPLEKISVIKQRISNYIDNKPEYWYPQAKIIVKDLEDLHIVRLAIWPCHRINHQDMAERWTRRAVLVEEVIKILLELDIQHRFYPLDINVRTMPTVVSSRVPPGWSQNQPA
What is the function of this protein?
Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer.  Exhibits a 6. 3-fold preference for chloride over sodium.  Regulates osmotic forces during pollen hydration and germination.
What are the official names of this protein?
Mechanosensitive ion channel protein 8, Mechanosensitive channel of small conductance-like 8, MscS-Like protein 8.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein.
Protein: SYC_BURM1
Sequence: MESLRIYNTLARDKQVFVPRQPGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIGYRVTYVRNITDIDDKIIRRAVENGETIKSLTDRFIDAMHEDEDALGIQRPDIEPRATQFIPQMLGMIERLEANGYAYQATDGDVNYSVRKFANYGKLSGKSLDDLRAGERVAANDAKEDPLDFVLWKRAKADDPEGASWESKYGMGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHHENEIAQSEGATGQTFVNYWLHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVMRFFIVRTHYRSPLNYSDVHLDDARASLTRLYTALKDVEPDALALDWNEPHAQRFAAAMNDDFNTPVAIATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRAFLQQASGAAQAGALSVDEIEAKIAARAAAKRAKDYAEADRIRAELLDAGVALEDKPGGSTEWRRV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_ECO57
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEPH_HUMAN
Sequence: MESGHLLWALLFMQSLWPQLTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITKETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQRKLRRNRRSILDDSFKLLSFKQ
What is the function of this protein?
May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis.  Implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1.
What are the official names of this protein?
Hephaestin.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: F16A2_HALMA
Sequence: MNTLDEIERAVKDTAHYVSGNLANYANRAAGENPSGEQQVGGDVWADDLFFDALAYIDGIGAYASEERSDVVDCGEGYSIAIDPLDGSSNLASNNSVGTIIGVYDAELPAAGREMVASLMVLYGPYTTLTIARSDRDVVQEHLLRDGHSERWGQFELPAEATVVGLAGKTGERSDAFNDIAQSFERDLKLRYGGATVADLAQVLEYGGLFGYPVTSGYPNGKLRVHFESAPLAYLVEAAGGASSDGSQSLLDVEPDGIHDRTPTFLGNAELVDELEAALSET
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 2, FBPase class 1 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_PECAS
Sequence: MITMIRRFIRLDAAAGMMLMMATVLAIALANWSVTAAGYQQFLMIPVEMRFGALEINKNLLLWINDALMAIFFLLIGLEVKRELVEGTLASRQQAMLPLAAAVGGMVFPALLFLLFNANDDVTRAGWAIPAATDIAFAIGVLTLLGKRVPAGLKVFLLALAIIDDLGAILIIALFYTQQVFWPALAGAVLAIAVLAYMNKLQVGKTSAYLLVGGVLWVCILKCGVHATLAGVIVGFFIPLRTSDGEPSPATSLEHGLQTWVAFLIVPLFAFANAGIVLQGIVLEKLFSPLSLGIAAGLLLGKPLGITLFSWLTIRLGYARLPVGVHFNQIVAVSVLCGIGFTMSIFITLLAFSGGDAELITYAKLGILLASGLAALLGYLALRGVLPALDKAV
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DSBD_ECO57
Sequence: MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPVDQAFAFDFQQNQHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTLPVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAASQPVSVPQQEQPTAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLIGLTIVFTLLAMSMFGLLTLQLPSSLQTRLTLMSNRQQGGSPGGVFIMGTIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYALGMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDVWGLRLWSALGVAFFGWAFITSLQAKRGWMRVVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNFTQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDPQVQKALADTVLLQANVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEOB_STREM
Sequence: MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISETAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIVYTSADPVLQIAAHEEVIPIEELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLLLITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTAMIGTSFLADLV
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.