PharMolix/UniProtQA huggingface dataset:
Protein: MOBA_CAMJD
Sequence: MQLNELNCVILCGGKSSRMGQDKSKLILKNQNLTQFQVNKFSKIFKNVYVSAKEDKFENHFNLIKDSLEFEVYSPMLALYSILSNFKNEFVFVLSVDSPKVGENELLKMLPFLEQNYKIIIAKTPLHKHPLCGFYHSSLAQTCKNFLEKNEQKIGFLFSEIKTKFVEFENEDAFLNLNFYEEYEKFKSELK
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_MARMS
Sequence: MEKRQELYAGKAKSVFRTDDPDKMVLVFRDDTSAFDGKRIEQLDRKGMVNNKFNAFIMTKLQEAGIPTHFEKLLSDTESLVKCLDMIPVECVVRNVAAGSLCRRLGVEEGITLTPPTFELFLKNDALGDPMINESHVESFGWAKASDLAKAKELTFKVNDVLKAIFAEGGMILVDYKLEFGLYKGEVLLGDEFSPDGCRLWDAKTKEKLDKDRFRQGLGGVIEAYEDVGRRIGIDFDA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: FIM1C_PHOV8
Sequence: MEVKSLLMVMATLTIAGCSQNEMTEMNPDTNRTIGLDVYTEVQTRGTETTTSTLKANAGFGIFAYQTSSAGWNSEKGNTTPNFMYNEHATWTSDSWGYTNLRFWPIDDKKITFFAYAPYESKPEVGTDQKITLSGQNAKGAPTITFEVKTSNNWKDMIDLVTDCHTAIQDQTNESNKGTVQFKFSHVLTQIANIKVKPDVNLGTDTKIFVTGLKLDPGSTTLYNKAVYKFDNDTWEAISPDASYFSTEQDLSDFLNKTTTDQWGYNKSSINVSDDQNATALFSDTEALYFIPVNNKNGTTNAGDLKLKINYDIVTKVTDTSNLTSTITNKEVSLPKNTFKKGTKHTYVLTIKMNAIKITVEDNMEGWTDDSDSDINVEK
What is the function of this protein?
Probably a component of the fimbrium tip.  Fimbriae are filamentous appendages on the cell surface that mediate cell adhesion and biofilm formation.
What are the official names of this protein?
Fimbrium subunit Fim1C.
What is the protein family that this protein belongs to?
Belongs to the bacteroidetes fimbrillin superfamily. Mfa-like family.
What are the subcellular locations of this protein?
Fimbrium. Cell outer membrane. Note=Probably synthesized as a palmitoylated precursor. Efficient export to the outer membrane and integration into fimbriae requires lipidation and subsequent proteolytic removal of the lipidated propeptide. Probably part of the fimbrium tip.
Protein: RNZ_STRTD
Sequence: MELQFLGTGAGQPSKARNVSSLVLKLLDEINEVWMFDCGEGTQRQILETTIKPRKVKKIFITHMHGDHIFGLPGFLASRSFQSSEEQTDLEVYGPVGIKQYVMTSIRTSGTRLSYHVHFKEIDENSLGLVMEDDKFAVYADKLDHTIFCVGYRVVQKDLEGTLDAEALKAAGVPFGPLFGQIKNGQDVVLEDGTKIIAKDFISAPKKGKVITILGDTRKTNASVRLGLGADVLVHESTYGKGDEKIAKSHGHSTNMQAAQVARDASAKRLLLNHVSARFLGRDIGKMAADAKTIFENTHIVRDLEEVEI
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: TFIP8_HUMAN
Sequence: MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKMLDEENI
What is the function of this protein?
Acts as a negative mediator of apoptosis and may play a role in tumor progression.  Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 8, TNF alpha-induced protein 8, Head and neck tumor and metastasis-related protein, MDC-3.13, NF-kappa-B-inducible DED-containing protein, NDED, SCC-S2, TNF-induced protein GG2-1.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITN1_ARATH
Sequence: MAASSYVDGERDMEKGGMILLQSSENQNPMIDPSPTPSPSATATAPALVLSNSGKRMDQAGKKKYVKQVTGRHNDTELHLAAQRGDLAAVQQILKDINSQMEGILSGEEFDAEVAEIRASIVNEVNELGETALFTAADKGHLDVVKELLKYSSRESIAKKNRSGYDPLHIAAIQGHHAIVEVLLDHDATLSQTFGPSNATPLVSAAMRGHTEVVNQLLSKAGNLLEISRSNNKNALHLAARQGHVEVIKALLSKDPQLARRIDKKGQTALHMAVKGQSSEVVKLLLDADPAIVMQPDKSCNTALHVATRKKRAEIVELLLSLPDTNANTLTRDHKTALDIAEGLPLSEESSYIKECLARSGALRANELNQPRDELRSTVTQIKNDVHIQLEQTKRTNKNVHNISKELRKLHREGINNATNSVTVVAVLFATVAFAAIFTVPGGDNNDGSAVVVGRASFKIFFIFNALALFTSLAVVVVQITLVRGETKAEKRVVEVINKLMWLASMCTSVAFLASSYIVVGRKNEWAAELVTVVGGVIMAGVLGTMTYYVVKSKRTRSMRKKVKSARRSGSNSWHHSDFSNSEVDPIFAI
What is the function of this protein?
Involved in salt stress tolerance.  May act through abscisic acid (ABA) signaling pathways and promote reactive oxygen species (ROS) production.
What are the official names of this protein?
Ankyrin repeat-containing protein ITN1, Protein INCREASED TOLERANCE TO NACL.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAA_BACC1
Sequence: MENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVLTITAPNEFARDWLESHYSELISETLYDLTGAKLAIRFIIPQSQAEEEIDLPPSKPNSAQDDSNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINDILK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU2_CALS4
Sequence: MAKQKFERTKPHVNVGTIGHVDHGKTTLTAAITLILSKAGLAQAKGYDEIDKAPEEKARGITINTTHVEYETAKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIVVFLNKADMVDDPELIELVEMEVRDLLNQYEFPGDETPIVVGSALKALECGCGKRECQWCGKIWELMDVVDEYIPTPERDIDKPFLMPVEDVFSITGRGTVATGRVERGKVKVGDEVEIIGLTTESRKTVVTGVEMFRKTLDEAQAGDNIGVLLRGIQKDEVERGQVLAKPGTIKPHTKFEAQVYVLTKEEGGRHTPFFNGYRPQFYFRTTDVTGTIQLPEGVEMVMPGDHVTLRVELITPIAMEEGLKFAIREGGRTVGAGVVSAIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu-B, EF-Tu-B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_SHEPW
Sequence: MGINFEVSRPKAGSDTNMSNTFHTIGLIGKPNHEGTNLTLKRLHHWLTMQGYSVLVEERVASDVGSHTHSVDLLEIGANCDLAIVVGGDGNMLGAARVLARFDIAVIGVNRGNLGFLTDLPPDTFEEALSKVLEGEFDTEQRFLLEAEVHRHGELKSSNTAVNEAVLHPGKIAHMIEFEVYIDDKFMYSQRADGMIVSTPTGSTAYSLSAGGAILTPNLEAMILVPMFPHTLSCRPIVVDACSIIKLVVSPHNGDNLEVSCDGHVNLSVLPGDEIIVKRSADTLRLIHPKGHNYFHVLRTKLGWGSKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD3_ARATH
Sequence: MFTDCSSSTTSRLIHLYNRNGVFLPRPSVSQFSLRTTASTWRCTLSIRSSSSPSAIVIDGKAEAKKIRDDIKIEVSRMKESIGVVPAEDSSEEEVLKYVSGFNDDPSVHGVLVQLPLPSHMDEQNILNAVSIEKDVDGFHPLNIGRLAMRGREPLFVPCTPKGCIELLHRYNIEFKGKRAVVIGRSNIVGMPAALLLQKEDATVSIIHSRTMNPEELTRQADILISAVGKPNMVRGSWIKPGAVLIDVGIKPVEDPSAAGGERLVGDICYVEASKIASAITPVPGDVGPMTIAMLLSNTLTSAKRIHNFQ
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 3, chloroplastic, Tetrahydrofolate dehydrogenase/cyclohydrolase 3.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRX1_VZVD
Sequence: MGSQPTNSHFTLNEQTLCGTNISLLGNNRFIQIGNGLHMTYAPGFFGNWSRDLTIGPRFGGLNKQPIHVPPKRTETASIQVTPRSIVINRMNNIQINPTSIGNPQVTIRLPLNNFKSTTQLIQQVSLTDFFRPDIEHAGSIVLILRHPSDMIGEANTLTQAGRDPDVLLEGLRNLFNACTAPWTVGEGGGLRAYVTSLSFIAACRAEEYTDKQAADANRTAIVSAYGCSRMETRLIRFSECLRAMVQCHVFPHRFISFFGSLLEYTIQDNLCNITAVAKGPQEAARTDKTSTRRVTANIPACVFWDVDKDLHLSADGLKHVFLVFVYTQRRQREGVRLHLALSQLNEQCFGRGIGFLLGRIRAENAAWGTEGVANTHQPYNTRALPLVQLSNDPTSPRCSIGEITGVNWNLARQRLYQWTGDFRGLPTQLSCMYAAYTLIGTIPSESVRYTRRMERFGGYNVPTIWLEGVVWGGTNTWNECYY
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly (By similarity).  Prevents also necroptosis and extrinsic apoptosis by sequestering host ZBP1 into large, insoluble supercomplexes and impairing its ability to interact with RIPK3 (PubMed:32649716).
What are the official names of this protein?
Triplex capsid protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: METC_ARATH
Sequence: MTSSLSLHSSFVPSFADLSDRGLISKNSPTSVSISKVPTWEKKQISNRNSFKLNCVMEKSVDGQTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTFPL
What are the official names of this protein?
Cystathionine beta-lyase, chloroplastic, CBL, Beta-cystathionase, Cysteine lyase, Cysteine-S-conjugate beta-lyase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYF_ANGEV
Sequence: MQNKNNYNWLKEWVIRSFLLLTLLTWPSVSNAYPIFAQQGYENPREATGRIVCANCHLAKKPVDIEVPQSVLPDTVFEAIVKIPYDMQVKQVLANGKKGGLNVGAVPILPQGFELAPSDRIPTEIKEKIGNLSFQNYSPDKKNIIIVGPVPGKKYSEIVFPILSPDPASNKESNFLKYPIYVGGNRGRGQIYPDGSRSNNTVYNASATGKVIKIFRKEKKGGYEITIEKTSDGRQVVDIVPPGPELIISEGEFLKVDQPLTNNPNVGGFGQGDAEIVLQDPLRIQGLLLFFASVVLAQIFLVLKKKQFEKVQLAEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MT2_MOUSE
Sequence: MDPNCSCASDGSCSCAGACKCKQCKCTSCKKSCCSCCPVGCAKCSQGCICKEASDKCSCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-2, MT-2, Metallothionein-II, MT-II.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: MUTL_SALG2
Sequence: MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRVDIDIERGGAKLIRIRDNGCGIKKEELALALARHATSKIASLDDLEAIISLGFRGEALASISSVSRLTLTSRTAEQAEAWQAYAEGRDMDVTVKPAAHPVGTTLEVLDLFYNTPARRKFMRTEKTEFNHIDEIIRRIALARFDVTLNLSHNGKLVRQYRAVAKDGQKERRLGAICGTPFLEQALAIEWQHGDLTLRGWVADPNHTTTALTEIQYCYVNGRMMRDRLINHAIRQACEDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQTETTLPLEEIAPAPRHVPENRIAAGRNHFAVPAEPTAAREPATPRYSGGASGGNGGRQSAGGWPHAQPGYQKQQGEVYRALLQTPATSPAPEPVAPALDGHSQSFGRVLTIVGGDCALLEHAGTIQLLSLPVAERWLRQAQLTPGQSPVCAQPLLIPLRLKVSADEKAALQKAQSLLGELGIEFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAQQTTFATVNIAQWIARNVQSEHPQWSMAQAISLLADVERLCPQLVKAPPGGLLQPVDLHSAMSALKHE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: LGT_STRE4
Sequence: MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSDDIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLFVYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMFIDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMRTDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BTAF1_HUMAN
Sequence: MAVSRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSANWDTRIAAGQAVEAIVKNVPEWNPVPRTRQEPTSESSMEDSPTTERLNFDRFDICRLLQHGASLLGSAGAEFEVQDEKSGEVDPKERIARQRKLLQKKLGLNMGEAIGMSTEELFNDEDLDYTPTSASFVNKQPTLQAAELIDSEFRAGMSNRQKNKAKRMAKLFAKQRSRDAVETNEKSNDSTDGEPEEKRRKIANVVINQSANDSKVLIDNIPDSSSLIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKSGGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGGLLGIKYALAVRQDVINTLLPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQTQKVPFIINTLWDALLELDDLTASTNSIMTLLSSLLTYPQVQQCSIQQSLTVLVPRVWPFLHHTISSVRRAALETLFTLLSTQDQNSSSWLIPILPDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYVVAAACPWMGAWLCLMMQPSHLPIDLNMLLEVKARAKEKTGGKVRQGQSQNKEVLQEYIAGADTIMEDPATRDFVVMRARMMAAKLLGALCCCICDPGVNVVTQEIKPAESLGQLLLFHLNSKSALQRISVALVICEWAALQKECKAVTLAVQPRLLDILSEHLYYDEIAVPFTRMQNECKQLISSLADVHIEVGNRVNNNVLTIDQASDLVTTVFNEATSSFDLNPQVLQQLDSKRQQVQMTVTETNQEWQVLQLRVHTFAACAVVSLQQLPEKLNPIIKPLMETIKKEENTLVQNYAAQCIAKLLQQCTTRTPCPNSKIIKNLCSSLCVDPYLTPCVTCPVPTQSGQENSKGSTSEKDGMHHTVTKHRGIITLYRHQKAAFAITSRRGPTPKAVKAQIADLPAGSSGNILVELDEAQKPYLVQRRGAEFALTTIVKHFGGEMAVKLPHLWDAMVGPLRNTIDINNFDGKSLLDKGDSPAQELVNSLQVFETAAASMDSELHPLLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEKVLPWLGAIDDSVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKFCSREYLNPLHYTGPPTERIRLQHQVKRHNLIVASYDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSATLSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLGNGSTSESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDGKAEKADTSTSGKASMKSILENLSDLWDQEQYDSEYSLENFMHSLK
What is the function of this protein?
Regulates transcription in association with TATA binding protein (TBP).  Removes TBP from the TATA box in an ATP-dependent manner.
What are the official names of this protein?
TATA-binding protein-associated factor 172, ATP-dependent helicase BTAF1, B-TFIID transcription factor-associated 170 kDa subunit, TAF(II)170, TBP-associated factor 172, TAF-172.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
Protein: HS105_PONAB
Sequence: MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKESLDQDPVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECYPNEKNSVNMDLD
What is the function of this protein?
Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release.  Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly.  Inhibits HSPA8/HSC70 ATPase and chaperone activities.
What are the official names of this protein?
Heat shock protein 105 kDa, Heat shock 110 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_ECO5E
Sequence: MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y624_PROMM
Sequence: MMDSTGMGCWGEERVLRLLQKRGWQLVSQRWSCRYGELDLVVEKQQRVLVVEVKSRRSRGLDHWGLCAFNKGKQLRLMRAIGCWLATHPYFAEHSLELVMALVPLPPSQNTLDWIRIDDLDIDAAD
What are the official names of this protein?
UPF0102 protein PMT_0624.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: TSC10_YARLI
Sequence: MIFPISEIPDKVTHSILEGVSALQNMSHTAFWSTVLGFLVVARIAVILATPKRRVLDIKGKKVVISGGSQGAGAALAELCYTKGANVVIVSRTVSKLEAQVQKIVTKHEPVFEGQTIRYISADLTKEEEAIRVFSEETMPAPPDVIFSCAGAAETGFILDFKASQLARAFSTNYLSALFFVHAGTTRMAKEPISPKNPRYVAIFSSVLAFYPLLGYGQYCASKAAVRSLIDSLRVEALPFNIRVVGVFPGNFQSEGFEEENKSKPEITRQIEGPSQAISAEECAKIVFAQMEKGGQMITTDLIGWILQSIALSSSPRSFSLLQIPLAIFMCIFSPVWNAFVNRDVRKYFHANTEYVTRHQRGGVGSENPTPQ
What is the function of this protein?
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
What are the official names of this protein?
3-ketodihydrosphingosine reductase TSC10, 3-dehydrosphinganine reductase, KDS reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: FTSP_ACTSZ
Sequence: MNYSRRSLFKKTLIATALSALPATLLAATKQPLVIPPLIESRRGKPVFLGLESAQVKLIDDKLVEVWGFNGQYLGPTVRVRQGDFVKLNYRNNLPHSVAMNIQGLQTNSNILGGIGHSLKPQQGWSPIVPITQPAATCYYHSCSLASSAYQNYRGLAGMWIIEDDESRQAQLPNKYGVNDIPLILQDLHLNKEGSQLFRQNEPHFYGDRLFVNGQEAPFINVGRGWIRLRILNASVSRSYPLQFDDERAFLLIAKDQGFLPEAKTVKSVLVGMGERVEILVDLNEGGNVSLIVGKKRSFLDKIDLFFNDNGELTDNTVLELRPEGLLSVFNGKPSYRFSAVATLPSQILQERAFHFDAENAMINNKRFDPRRIDVNAKQGSAERWTLSATNAMGFRIQGAKFVVESRDDVATPGNELVWQDTLWFERTAKILVKFEHSASNSQPFTFGSSDLMQADKGALGLIVVQ
What is the function of this protein?
Cell division protein that is required for growth during stress conditions.  May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
What are the official names of this protein?
Cell division protein FtsP.
What is the protein family that this protein belongs to?
Belongs to the FtsP family.
What are the subcellular locations of this protein?
Periplasm. Note=Localizes to the division septum.
Protein: EDN3_RAT
Sequence: MELGLWLLLGLTVTSAAAALPAQPGNAGQERGPGRSGDQEEKRVPAHHRPRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNHRGSLRGKRSSGPVPESSQSSPQTRLRCACSGVDDKACAYFCAHVTSYSRRAEKAAAEEKQETGGPRQRLKSRTDKVHQP
What is the function of this protein?
Endothelins are endothelium-derived vasoconstrictor peptides.
What are the official names of this protein?
Endothelin-3, ET-3, Preproendothelin-3, PPET3.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLYCO_VSIVA
Sequence: MKCLLYLAFLFIGVNCKFTIVFPHNQKGNWKNVPSNYHYCPSSSDLNWHNDLIGTAIQVKMPKSHKAIQADGWMCHASKWVTTCDFRWYGPKYITQSIRSFTPSVEQCKESIEQTKQGTWLNPGFPPQSCGYATVTDAEAVIVQVTPHHVLVDEYTGEWVDSQFINGKCSNYICPTVHNSTTWHSDYKVKGLCDSNLISMDITFFSEDGELSSLGKEGTGFRSNYFAYETGGKACKMQYCKHWGVRLPSGVWFEMADKDLFAAARFPECPEGSSISAPSQTSVDVSLIQDVERILDYSLCQETWSKIRAGLPISPVDLSYLAPKNPGTGPAFTIINGTLKYFETRYIRVDIAAPILSRMVGMISGTTTERELWDDWAPYEDVEIGPNGVLRTSSGYKFPLYMIGHGMLDSDLHLSSKAQVFEHPHIQDAASQLPDDESLFFGDTGLSKNPIELVEGWFSSWKSSIASFFFIIGLIIGLFLVLRVGIHLCIKLKHTKKRQIYTDIEMNRLGK
What is the function of this protein?
In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and endosomal membrane.
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host membrane; Single-pass type I membrane protein. Note=The cytoplasmic domain sorts the protein to neurons dentrites instead of axons. When expressed in ex vivo polarized cells like epithelial cells, it sorts the protein to the basolateral side.
Protein: RS20_ENT38
Sequence: MANIKSAKKRAVQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQNAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQISKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.