PharMolix/UniProtQA huggingface dataset:
Protein: RPRML_MOUSE
Sequence: MNVSFLNHSGLEEVGGDARATLGNRSHGLGTWLDCCPGGAPLTASDGVPAGLAPDERSLWVSRVAQIAVLCVLSLTVVFGVFFLGCNLLIKSESMINFLMQERRPSKDVGAAILGLY
What are the official names of this protein?
Reprimo-like protein.
What is the protein family that this protein belongs to?
Belongs to the reprimo family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: BETB_BURCM
Sequence: MSVYGLQRLYIGGGYVDATSGKTFDTFDPATGELLAQVQQASAADVDRAVASAREGQREWAAMTAMQRSRILRRAVDLLRERNDELAAIETRDTGKPIGETLAVDIVTGADVIEYYAGLATAIEGLQVPLRAESFVYTRREPLGVCAGIGAWNYPIQIACWKTAPALAAGNAMVFKPSEVTPLTALKLAEIYTEAGVPAGVFNVVQGDGSVGALLTGHPDIAKVSFTGGVETGKKVMSLAGASSLKEVTMELGGKSPLIVFEDADLDRAADIAVTANFFSSGQVCTNGTRVFVHRSVKDAFTQRVLERVKRIRVGKPTDAATNFGPLVSAAQLDKVLGFIDSGKAEGAKLLAGGTRLTDGHFASGQYVAPTVFGDCRDDMKIVREEIFGPVMSILDFESEDEVIARANDTHYGLAAGVVTENLSRAHRTIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGITTLEHYTRIKSVQVELGRYNPVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: SECA_DELAS
Sequence: MATNFLTKLFGSRNDRLLKQYRKTVVRINAMEPDYEKLSDEALRAKTQEFKERVAKGESLDDLLPEAFAVVREGSKRVMKMRHFDVQLLGGMALHYGKIAEMRTGEGKTLTATLPVYLNALSGNGVHVVTVNDYLANRDATWMAKLYNFLGLSVGINLPNMPREEKQAAYNSDITYGTNNEYGFDYLRDNMVYESGDRVQRVLNYAIVDEVDSILIDEARTPLIISGQAEDHTAMYVAMNKIVPNLVRQEGEADPRTGEGVTKPGDFTVDEKSHQVFLTDQGYEAAERLLGHAGMIAEGASLYDPANITLVHHLYAALRANNLYHRDQHYVVQNGEIVIVDEFTGRLMAGRRWSDGLHQAVEAKEGVTIQAENQTMASITFQNYFRLYGKLAGMTGTADTEAYEFQEIYGLETMVIPPNRPSKRDDQLDRVYKTTREKYEAAIRDIRECYERGQPVLVGTTSIENSEIIDELLNKENLPHQVLNAKQHEREADIVAQAGRPGMITIATNMAGRGTDIVLGGNIEKQVAAVEADESLSEAERQQRIEQMRADWKIEHDKVSALGGLRIIATERHESRRIDNQLRGRSGRQGDPGSSRFYLSLDDALMRIFAGDRVRAIMDRLKMPDGEAIEAGIVTRSIEGAQRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNEILDASDLYEMITVMRDDVVSDLVRQYVPAESMEEQWDLAGLEKALESEWRIQLPLQSQVQSAHAITDEEILEKVLQAAREVFDAKVELIGRENFTQFQRAVLLQSFDTNWRDHLSALDYLRQGIHLRGYAQKQPKQEYKREAFELFRQLIDQVKTEVTRVLMTVQVQSREQVEQATEALEQRSAHSLEHMTYGAPSDGDIGGSVEDEPLELPEGARVGRNDPCPCGSGKKYKQCHGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: UGP1_CANAL
Sequence: MATTGKRHAKSQSTYAFDNTATNVTASQMRNALNNLADTVENPEQTTRFENEMDNFFTLFRRYLTEKASGSTLDWDKIRSPSSDEVVEYGDLNSANNSANLSKLAVLKLNGGLGTSMGCVGPKSVIEVRDGNNFLDLAVRQIEHLNRKYDADVPLLLMNSFNTDADTEKIIKKYQSHRIRVKTFNQSRFPRIYKDSLLPVPESFDDSLEAWYPPGHGDLFEALVQSGELDALLAQGREILFVSNGDNLGATVDSKILDHMIETGAEYIMELTPKTRADVKGGTLINYQGEVRLLEIAQVPKEHVEEFKSIKKFKYFNTNNLWINLRAIKKLVEANAIEVEIIPNQKTISHGKSDINVLQLETAVGAAIRHFKGAHGVVVPRSRFLPVKTCSDLLLVKSDLFYLEHGALVLDPTRDGFSNPLIKLGSHFKKVSGFQSRIPYIPKILELDHLTITGNVTIGKGVQLKGTVIIVCNDGDKIDIPNGAILENVVVTGNLTILEH
What is the function of this protein?
Plays a central role as a glucosyl donor in cellular metabolic pathways.
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, UGPase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 1 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Localizes to yeast but not hyphal cell surface.
Protein: GAP45_PLAF7
Sequence: MGNKCSRSKVKEPKRKDIDELAERENLKKQSEEIIEEKPEEVVEQVEETHEEPLEQEQELDEQKIEEEEEEPEQVPKEEIDYATQENKSFEEKHLEDLERSNSDIYSESQKFDNASDKLETGTQLTLSTEATGAVQQITKLSEPAHEESIYFTYRSVTPCDMNKLDETAKVFSRRCGCDLGERHDENACKICRKIDLSDTPLLS
What is the function of this protein?
Component of the glideosome complex, an inner membrane complex structure involved in parasite gliding motility and host cell invasion (PubMed:16321976, PubMed:16750579, PubMed:19576251, PubMed:22479457).  During the asexual blood stage, required in schizonts to recruit MTIP and MyoA to the inner membrane complex where they assemble with GAP50 to form the glideosome complex (PubMed:19576251, PubMed:29970464).  By regulating the formation of the glideosome, plays an essential role during merozoite invasion of host erythrocytes (PubMed:29970464).
What are the official names of this protein?
Glideosome-associated protein 45, PfGAP45.
Protein: TRPC_PROM3
Sequence: MEIRRRPPNPSVKVAHLQYAIPHADAEPRHILEKIVWEKDREVETARQRVPLETLKSQIADLPIPRDFIAALRQASVAPAVIAEVKKASPSQGVIRADFDPVLIANAYAEGGASCLSVLTDKSFFQGGFEVLVEVRQTVGLPLLCKDFILTPYQLYQARAAGADAALLIMAILSDQDLTYLSKVANSLGLTVLVEVHDAEELERVLNLGGFPLIGINNRDLTTFETDLETTETLSKQFATRLKQQGVLLVSESGLFNRADLDRVQAVGAEAVLVGEALMRQSDVCAGLKQLMIGDEGTSNS
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: NAGB_YERPP
Sequence: MRLIPLRNTAEVGKWAARHIVNRINAFKPTAERPFILGLPTGGTPMEAYKYLIAMHKAGEVSFKHVVTFNMDEYVGLPKEHPESYYTFMHTNFFDHVDIPAENINLLNGNAADIDAECRRYEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLASRTRIKTLTQETRIANSRFFGGDANLVPKYALTVGVGTLLDAEEVMILVTGHGKAQALQAAVEGSINHMWTISCLQLHAKAIMVCDEPSTMELKVKTVKYFRELEAENVKDL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: CHEB1_METAC
Sequence: MRTLIVDDSAFMRMAIRSMLASSPDIKIVGDACNGKEAVEKAKSLHPDVVIMDVNMPVMDGLTAVKTIMNTSPVPIIMFSTLTTEGSKEALEALHLGAIDFTAKSESHHDVNKAEKELVDKIRNIHSSNPNLLRLINMRKFKGEVVRGKWRCAGDFGILIGSSTGGPSSLEQVIPRLPGDLPAPVFVVQHMPEGGFCRQMAERLNFLSELEVKEARNNEKVTAGIVYVAPGGYHMTVRKALDVTRIKLIKSQPVHAVMPAVDVTAESMLAVYGKNIVASILTGMGFDGASGFKTIRDAGGSTIACSEDTCVIFGMPKAAIEAGAIDVVKPIFEIPEEIVKRLEAKCNGK
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABCBA_HUMAN
Sequence: MRGPPAWPLRLLEPPSPAEPGRLLPVACVWAAASRVPGSLSPFTGLRPARLWGAGPALLWGVGAARRWRSGCRGGGPGASRGVLGLARLLGLWARGPGSCRCGAFAGPGAPRLPRARFPGGPAAAAWAGDEAWRRGPAAPPGDKGRLRPAAAGLPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNPTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYSELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAVLDQGKITEYGKHEELLSKPNGIYRKLMNKQSFISA
What is the function of this protein?
Catalyzes the export of an unknown physiological substrate from the mitochondrial matrix to the cytosol in an ATP-dependent manner (PubMed:33253225).  May also transport the heme analog Zn (II) mesoporphyrin (ZnMP) in an ATP dependent manner but can't export the heme precursor 5-aminolevulinic acid (ALA) from mitochondria (PubMed:33253225).  Plays a role in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX).  In turn participates in hemoglobin synthesis and also protects against oxidative stress (PubMed:28808058, PubMed:22085049).  In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria (PubMed:28315685).
What are the official names of this protein?
ATP-binding cassette sub-family B member 10, mitochondrial, ABC-mitochondrial erythroid protein, ABC-me protein, ATP-binding cassette transporter 10, ABC transporter 10 protein, Mitochondrial ATP-binding cassette 2, M-ABC2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL17_MICAN
Sequence: MRHRCKVPQLGLPADQRKALLRSLATQLILHGQITTTLAKAKAVRAEVDHIITLAKDGSLSARRQAMGYIYDKQLVHALFEGAQARYGNRNGGYTRVVRTLRRRGDNAPMAIIELM
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: CAMA_PSEPU
Sequence: MNANDNVVIVGTGLAGVEVAFGLRASGWEGNIRLVGDATVIPHHLPPLSKAYLAGKATAESLYLRTPDAYAAQNIQLLGGTQVTAINRDRQQVILSDGRALDYDRLVLATGGRPRPLPVASGAVGKANNFRYLRTLEDAECIRRQLIADNRLVVIGGGYIGLEVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDIRTGTQVCGFEMSTDQQKVTAVLCEDGTRLPADLVIAGIGLIPNCELASAAGLQVDNGIVINEHMQTSDPLIMAVGDCARFHSQLYDRWVRIESVPNALEQARKIAAILCGKVPRDEAAPWFWSDQYEIGLKMVGLSEGYDRIIVRGSLAQPDFSVFYLQGDRVLAVDTVNRPVEFNQSKQIITDRLPVEPNLLGDESVPLKEIIAAAKAELSSA
What is the function of this protein?
The oxidation of camphor by cytochrome P450-CAM CamC requires the participation of the flavoprotein, putidaredoxin reductase CamA, and the iron-sulfur protein, putidaredoxin CamB, to mediate the transfer of electrons from NADH to P450 for oxygen activation.
What are the official names of this protein?
Putidaredoxin reductase CamA, Pdr, Putidaredoxin--NAD(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
Protein: AOFA_RAT
Sequence: MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADRQAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKDVPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
What is the function of this protein?
Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:18391214, PubMed:9162023).  Preferentially oxidizes serotonin (PubMed:20493079).  Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline (PubMed:18391214).
What are the official names of this protein?
Amine oxidase [flavin-containing] A, Monoamine oxidase type A, MAO-A.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: LDHA_SPHAG
Sequence: MSTKEKLIGHVMKEEPIGSRNKVTVVGVGMVGMASAVSILLKDLCDELALVDVMEDKLKGEAMDLQHGSLFLKTHKIVADKDYSVTANSRVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVAWKLSGFPRHRVIGSGTNLDSARFRHIMGEKLHLHPSSCHGWIVGEHGDSSVPVWSGVNVAGVSLQTLNPKMGAEGDSENWKAVHKMVVDGAYEVIKLKGYTSWAIGMSVADLVESIVKNCTKCTQCPRWSRGMHGVKDEVFLSVPCVLGNSGLTDVIHMTLKPEEEKQLVKSAETLWGVQKELTL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_SHEHH
Sequence: MKDLLKFLKQQSKTEEFDGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQMLTEENYLDALEEYGDEFDAKMGAEAVLELLRAIDLEKEIEMMREELPSINSETRRKKVTKRLKLVEAFFTSGNKPEWMILKVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVPEVWDVLDDVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARSLMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGKGEGMAFSDVAEAEKAYRTGVAELHARVKVRITETATNEAGEKVKTRRIVDTTVGRALLSQILPKGLSYDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFHFATISGASVGIDDMVIPDEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMANLSKETVINRDGEEEQQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVSQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVIEDDCGTFEGLTMKPLIEGGDVVEPLRERVLGRVVAQDVFKPGTAEVLVPRNTLLDEAWCDIIEDNSIDEMIVRSVISCDTDFGVCKFCYGRDLARGHIINQGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGTLKLHNAKFVTNSNGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEDDGVAAGEIIAKWDPHTHPIITEVAGSIKFVDMIEGVTMTRQTDELTGLSSIVVLEVGQRPTAGKEMRPMIRLVAADGSDLMIPGTEVPAQYFLPGHAIVNLDDNAPINVGDALARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEVSGTISFGKETKGKRRLVITPADGGEHYEEMIPKWRNLNVFEGEKVERGEVIADGAEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCEIVDAGDSEFLPGEQAEVSRVKIANRELEAQGKQPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDKLRGLKENVIVGRLIPAGTGYSYHQKRAEAAAKPAVTEATSISASEAEQNLADLLNLAGSND
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RL19_BARHE
Sequence: MNIIAQLEAEQCAKIAAKRQLPAFQPGDTVRVMVRVTEGTRTRVQAYEGVCIARSGGGLNETFTVRKISYGEGVERVFPVYSPLIEGVELVRRGKVRRAKLYYLRNLRGKAARITEKKDQRKKSAKIVEKEQEALVRVEAPAHATE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: COXX1_RHILO
Sequence: MSTREGRLKDTSIRLSEATAADFFALLKPRVMALAVFTAFVGLMVAPGAVNPVIAVIAIAAIAIGAGAAGALNMWYDADIDALMSRTSKRPVPSGRVTPGEALGFGLVLSALSVMTLGVLVGWLAASLLAFTIFFYIVIYTMWLKRSTPQNIVIGGAAGALPPVIGWAAATGAVGVESLVLFLIIFLWTPPHFWALALFKVGDYAAAGIPMMPNVAGPASTRRQILAYALLLAPVGVLPWAFGFTSGYYGIASAALGVGFIWHSWKVRAASETELKPAKALFAYSIVYLFAVFAALLADTIAMRALMSVGA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 1, Heme B farnesyltransferase 1, Heme O synthase 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DUT_EHV1B
Sequence: MASVTNLVDSIVVVECGERWRARAEAAGRLLVLINNHTVELSGEHGSAGEFYSVLTDVGVRVACSSGYAIVLTQISGLLPVEPEPGNFSNVTFPENSAKYYTAYGIVDSGYRGVVKAVQFAPGINTSVPPGQMSLGLVLVKLARKSIHVTSIGSTRDGRTSEANLFYDYFAPKRVEDAGYDISAPEDATIDPDESHFVDLPIVFANSNPAVTPCIFGRSSMNRRGLIVLPTRWVAGRTCCFFILNVNKYPVSITKGQRVAQLLLTEDIDDALIPPTVNYDNPFPTYSPSESTKAPQSPVLWKFTTDFDREAPSSLRADGGFGSTGL
What is the function of this protein?
Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: VU1_HHV6U
Sequence: MFCGSPFLGISSWSLASAALCPPSCSFSAGRDLRCDAEVPEVKWTAFVRTLVTRPLSADDVWDFVSTFAHCRLALSWPVGAELRFATSDMLGITQAEVAKLSRRYGCCPGMDLTVIGVTIFAEVSALVLVGECGEIYAFNGVFDDALYRLAEDAFGLWKHGLRRFEPVYGSKCLTETGASFFGGMSGVDDVLAFAVSFDKALVPLPWPRGAFFEFAVPGRPEKRWRLIPGGGVAVVIGRFFGRGVTSPLLRRQRVLMDQVGRVYAASLDGGAVVRLSDSFRAFLAMGVRKLFKNHRFPPGHLWTMQLPVTCVHAPVIDLPAVYQLSPHMVERGMPVASCEASTVVRGDCEETETEESTSGDSVLVC
What are the official names of this protein?
Protein U1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: COFE_METAC
Sequence: MKFEAIAVEKIPLIRKGDDLPYIICERIELQDRDIIVIASTIVAKAEGETFRLEDITPGEEALAIASRTGKDARFIQAVLSRSREVFVEAPFMLVTTLAGHTCVNAGVDESNIEHGFLLYPPKNPDSSASKLGERLESISGKKLSVIITDTNGRAFKIGQTGVAIGIYKIKPIKRWIGEKDLFDKVLEITEEAVADELAGAANLLMGEGAGGIPVAVIRGLDYYCEEEISMSENYRPEDMDVIKKGLRCLQKKN
What is the function of this protein?
Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
What are the official names of this protein?
Coenzyme F420:L-glutamate ligase, Coenzyme F420-0:L-glutamate ligase, Coenzyme F420-1:gamma-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the CofE family.
Protein: VMPA3_LOXIN
Sequence: MTTMSFFTVLSVAVCLCIEAGVEGSRLNGRDMLMQEESPLMERNALKYDSRLWPDGVVIYEFTSLRFYRKLIKRVMQHIADNTCITFKERTNEKGYVNIYNGKLFTCFADMGYYPFKQRLSLGLGCRSFGAILHELGHVLGLYHEQQRPDRDDYVIVYKDNIQTGALRDYEKRFENNTRVIGPFDYDSIMIYGETDARKSGSVTMKVKKPGATLVNASLKHELTALDIKKINTLYNCPGKDKF
What is the function of this protein?
Zinc metalloprotease.  Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro.  Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins.  Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey (By similarity).
What are the official names of this protein?
Astacin-like metalloprotease toxin 3, Loxosceles astacin-like protease 3, LALP3.
What are the subcellular locations of this protein?
Secreted.
Protein: KPRS_HALH5
Sequence: MANYGDPNLKVFTLNSNKGLAYEITERIGVPMGKSSVTRFSDGEVQINIEESIRGCDVFLIQSTAAPANEHIMELLIMIDAVKRASAKTINVVIPYYGYARQDRKARAREPITAKLVANLLETAGATRVLTLDLHATQIQGFFDIPVDQLMGVPILAEFFEKKGLDDVVVVSPDHGGVVRARKLADRLKAPIAIIDKRRPKPNVAEVMNIVGHIEGKTAIIIDDIIDTAGTITLAANALVEHGAKEVYACCTHPVLSGPAIERIKNSKIKELVVMNTIELEEEKLIDKITTLSVAPLMAEAIVRVHEHSSVSLLFD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
Protein: GLSA2_BACCR
Sequence: MIKDSSVQVEGQEKVCLDQWVAHYRAYAAKGRSASYIPALGEINVSQLGICIVKPDGTMIKSGDWEIPFTLQSISKVIGFIAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPFNPMINAGAITIASLLPGTSVQEKLESLYVLIEKMIEKRPAINEIVFQSEWETAHRNRALAYYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVARLTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPAIDEYGNSLPGIMLLEHIAKEWDLSIF
What are the official names of this protein?
Glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: RLMN_COXBR
Sequence: MTEKINLLNLSEPELQGFIASQGQPLYRATQLLQWIHQRGVTDFSLMTDLSKPFRQQLSEASFVRVPELALERVSADGTHKWLFRLADNNKIETVFIPDRKRGTLCVSSQVGCALNCSFCATGKEGFNRNLTLAEIIGQVWLAARLLKSPYKITNVVMMGMGEPLLNYEAVVAAMHLMMHDHAYGLSKYRVTLSTSGVIPAMRRLREESPVSLAVSLHAPNDALRNVLIPLNKKYSLDQLIPLCRDYYSRGSKRCVTFEYVMIEGMNDRLIDAKQLIRLLADVPCKINLIPFNSFQGTAYRCSTESAISVFQKCLMDAGFNTRVRRTRGDDIAGACGQLAGQFHDRTGRHQRWVQKQGHDFNRPIPAIDH
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_COLP3
Sequence: MMIPAIDLIGGEVVRLYQGDYAQKTNYQYTVQDRQQAYAESGATVMHFVDLDGAKDSTKRQLKTLKTVVNHPSMIIQVGGGVRCEDDVKQLLALGADRVVIGSLAIKQPELVTQWVKTYGCEKIVLALDIKIDAQGNKTLPTHGWIEDSGVNLEDLLAQYQDAGIKHVLCTDISKDGTLTGTNVDLYSEVCAKYPDIDWQASGGIGSLADIKALIPTGVSGVILGRSLLEGKFTLEEAIACWPKTSANNAESNTSSNTGDK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.