PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_PSYIN
Sequence: MSNPFAGNTDPISNALIPMVVEQTAKGERSYDIYSRLLKERVIFLTGPVEDHVANVIAAQLLFLESESPEKDIFIYINSPGGSISAGMAIYDTMQFIKPDVSTVCMGMAASMGAFLLASGAPGKRHCLPNAKVMIHQPLGGFQGQASDFEIHAKEILATKHRMNELLAFHTGKDIEIIAQDTDRDNFMRASEAVEYGIVDSVLTHRK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLUC_CALMI
Sequence: HSEGTFSSDYSKYLDSRRAKDFVQWLMST
What is the function of this protein?
Glucagon plays a key role in glucose metabolism and homeostasis.  Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.
What are the official names of this protein?
Glucagon.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: COX10_KLULA
Sequence: MSLVIQPLLMRALNPNLSSILISGRGFSLIQHRRFAFRAGSGNNNSEQNQVHINTAPIEFTANLLAGKNETEAETEGLKGTALKALRCNDTTSDSEPQHNMENLPFKVKLVDKGQRKQIKESKARVEPRPEVSLKKTYIEPYLQLSKPRLTVLVMLSAICSYALSPYPATVLQLLSLTVGTTLCSASANAINMGREPDFDRQMIRTQARPVVRGIVSPNQAFKFATAAGTLGTSILWLGVNPTVAFLGFSNIALYAWLYTSLKRKHIINTWVGALVGAIPPLMGWAASSPLSHPGAWCLAGLLYAWQFPHFNTLSHNIRNEYKNAGYVMTAWKNPKLNARVALRYSLLMFPLCFGLSYFNVTDWYYQLDSAFVNAWMSLWAFKFYFQQKRNYSKEIYNNKTEFNKGLAMANVYARRTFWVSVLHLPAVLILAILHKKDRWDWLFEDKKQLSA
What is the function of this protein?
Converts protoheme IX and farnesyl diphosphate to heme O.
What are the official names of this protein?
Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SPY4_HUMAN
Sequence: MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLALTTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF
What is the function of this protein?
Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras (PubMed:12027893).  Probably impairs the formation of GTP-Ras (PubMed:12027893).  Inhibits Ras-independent, but not Ras-dependent, activation of RAF1 (PubMed:12717443).  Represses integrin-mediated cell spreading via inhibition of TESK1-mediated phosphorylation of cofilin (PubMed:15584898).
What are the official names of this protein?
Protein sprouty homolog 4, Spry-4.
What is the protein family that this protein belongs to?
Belongs to the sprouty family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor) (By similarity). Colocalizes with TESK1 in vesicular spots in the cytoplasm (PubMed:15584898).
Protein: PSRP_BURTA
Sequence: MLPTVFIVSDGTGITAETFAHSILSQFDQKFRLVRVPFIDSIEKAYGTVQKIDDAAQHDGRRPIVFTTLVDGESNEIVKRSNALVLDMFQRFVEPLEQELQLKSSHAMGRVHQNADTEEYKTRIEAINFSLAHDDGQSNRNLADADVILIGVSRSGKTPTSLYLAMQYGVKAANYPLIPEDFERGKLPTPLHPHRDKLFGLSIDPMRLSEIRNERRPGSKYAAPENCRYEINEAEAMMRREGVKWLSSTHKSIEEIATTILQEIKLERQSY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: DHYS_SULIM
Sequence: MINREDLLKNPVEDIALSDLEKYSDIVNVFDKIYGFSSEGIVRGSKILKEMIKDADLRFLSFTANLVSTGLRGLFADLVKRGYFNIIVTTGGTIDHDLARSFGGVYYKGSFDIDDAMLKDLEIHRLGNVLVPFESYGKVIEEIVRKFLPEIAKDKKEIPAYELLWEFGKRISDSNSILRAAYEKKVPVIVPGIVDGSFGTNLFIQSQFLNFKINLFEDMRLIKDLVFSCKKSGALIIGGGISKHHTIWWNQFKDGLDYAVYVTTAQEYDGSLSGAKPREAISWNKIRPNAKHATIYGDATIIVPILAASLLS
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: ACSA_YERPP
Sequence: MSQIHKHPIPAAIAEHALITPEKYQHYYQQSVQNPDEFWGEQGKIIDWIKPYKTVKNTSFDPGHVSIRWFEDGTLNLAANCLDRHLAERGDQTAIIWEGDDPNQSKTVTYKQLHHDVCQFANVLKSLGVKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPDAVAGRIIDSHSKLVITADEGIRAGRAIPLKKNVDEALKNPAITSIKNVVVFQRTGNASYWEDGRDVWWHDLIKEASADCPPEEMNAEDPLFILYTSGSTGKPKGVVHTTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGAITLMFEGVPNYPGVNRLSQVVDKHKVNILYTAPTAIRALMAEGDKAIEGTKRDSLRIMGSVGEPINPEAWEWYYNKIGNSKCPIVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNLGNPQEGVAEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKGMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGVPHNIKGQAIYAYITLNHGEEPTPELYTEVRNWVRKEIGPLATPDILHWTDSLPKTRSGKIMRRILRKIATGDTSNLGDTSTLADPSVVEKLLEEKQSMQTPS
What is the function of this protein?
Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt.  Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: UPP_LIMRJ
Sequence: MGKFEVLDHPLIQHKLTMIRDKNVGTKFFRETVKEISTLMAYEVARDMPLKDVEIETPIAKTTQKELAGKKVAIIPILRAGIGMVDGMTDLIPAAKIGFIGMYRDEETLKPHEYFVKLPNDITERQLFIVDPMLATGGSAMMAIEALKKRGCSEKNMKFACLVAAPEGVKAVRDAYPDVDIYTAGLDDHLNEDGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: VPED_ARATH
Sequence: MSSPLGHFQILVFLHALLIFSAESRKTQLLNDNDVESSDKSAKGTRWAVLVAGSNEYYNYRHQADICHAYQILRKGGLKDENIIVFMYDDIAFSSENPRPGVIINKPDGEDVYKGVPKDYTKEAVNVQNFYNVLLGNESGVTGGNGKVVKSGPNDNIFIYYADHGAPGLIAMPTGDEVMAKDFNEVLEKMHKRKKYNKMVIYVEACESGSMFEGILKKNLNIYAVTAANSKESSWGVYCPESYPPPPSEIGTCLGDTFSISWLEDSDLHDMSKETLEQQYHVVKRRVGSDVPETSHVCRFGTEKMLKDYLSSYIGRNPENDNFTFTESFSSPISNSGLVNPRDIPLLYLQRKIQKAPMGSLESKEAQKKLLDEKNHRKQIDQSITDILRLSVKQTNVLNLLTSTRTTGQPLVDDWDCFKTLVNSFKNHCGATVHYGLKYTGALANICNMGVDVKQTVSAIEQACSM
What is the function of this protein?
Asparagine-specific endopeptidase that may be involved in processing of proteins targeted to vacuoles (By similarity).  Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds (PubMed:12417707, PubMed:14688293).  Exhibits a caspase-1-like activity in extracellular granules.  At the early stage of seed development, required for the formation of the seed coat, by regulating cell death of specific cell layers in inner integument (PubMed:15705955).
What are the official names of this protein?
Vacuolar-processing enzyme delta-isozyme, Delta-VPE, Asparaginyl endopeptidase delta-VPE.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Secreted, cell wall. Vacuole. Note=Localized to electron-dense structures inside and outside the walls of seed coat cells that undergo cell death.
Protein: HCHA_STAA9
Sequence: MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVADLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_GEOSE
Sequence: MKKKCIAMLLAGGQGSRLRSLTTNIAKPAVPFGGKYRIIDFTLSNCTNSGIDTVGVLTQYQPLLLHSYIGIGSAWDLDRRNGGVTVLPPYSVSSGVKWYEGTANAVYQNINYIEQYNPDYVLVLSGDHIYKMDYQHMLDYHIAKQADVTISVIEVPWEEASRFGIMNTNEEMEIVEFAEKPAEPKSNLASMGIYIFNWPLLKQYLQIDNANPHSSHDFGKDVIPMLLREKKRPFAYPFEGYWKDVGTVKSLWEANMDLLDENNELDLFDRSWRIYSVNPNQPPQYISPEAEVSDSLVNEGCVVEGTVERSVLFQGVRIGKGAVVKESVIMPGAAVSEGAYVERAIVTPDSIIPPHSSVCPEDADDVVLVTAEWLKQSNEETARKDEA
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: KAD_VEREI
Sequence: MRLILLGAPGAGKGTQAGFICQRYGIPQISTGDMLRAAVKAGTPLGLQAKAVMDSGSLVSDDIIIHLVKERIAQPDCAQGFLFDGFPRTIAQADALKAAGVRLDYVLEIDVPFEAIIERMSGRRSHPASGRTYHVRFNPPKIDGKDDLTGEALLQREDDKEETVRKRLQVYSAQTRPLVDYYSHWARVEPAAAPRYRCISGTGRVDEITARALQALAC
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA2_STAA8
Sequence: MTKEYATLAGGCFWCMVKPFTSYPGIKSVVSGYSGGHVDNPTYEQVCTNQTGHVEAVQITFDPEVTSFENILDIYFKTFDPTDDQGQFFDRGESYQPVIFYHDEHQKKAAEFKKQQLNEQGIFKKPVITPIKPYKNFYPAEDYHQDYYKKNPVHYYQYQRGSGRKAFIESHWGNQNA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA 2, Protein-methionine-S-oxide reductase 2, Peptide-methionine (S)-S-oxide reductase 2, Peptide Met(O) reductase 2.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: AROQ_FRATM
Sequence: MDVLVINGPNLNLLGTRQPRFYGHKTLADINNDLLKIAKENNINIDFYQSNHEGQIIDKIQQTAAKIIIINPAAFTHTSVAIRDAFLAINKPFIEIHLSNIYNREEFRTKSFLSDIAYGCIFGFGPNGYTLALIEAINYINMKGE
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: LIS1_PANTR
Sequence: MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDMNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQTVKVWECR
What is the function of this protein?
Regulatory subunit (beta subunit) of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)), an enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and participates in PAF inactivation.  Regulates the PAF-AH (I) activity in a catalytic dimer composition-dependent manner (By similarity).  Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome.  Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate.  Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates.  During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules.  Also required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors.  May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing.  Required for dynein recruitment to microtubule plus ends and BICD2-bound cargos.  May modulate the Reelin pathway through interaction of the PAF-AH (I) catalytic dimer with VLDLR (By similarity).
What are the official names of this protein?
Platelet-activating factor acetylhydrolase IB subunit alpha, Lissencephaly-1 protein, LIS-1, PAF acetylhydrolase 45 kDa subunit, PAF-AH 45 kDa subunit, PAF-AH alpha, PAFAH alpha.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus membrane. Note=Localizes to the plus end of microtubules and to the centrosome. May localize to the nuclear membrane. Redistributes to axons during neuronal development. Also localizes to the microtubules of the manchette in elongating spermatids and to the meiotic spindle in spermatocytes.
Protein: EMTA_SHISS
Sequence: MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RTNLI_ARATH
Sequence: MPIFTGSSSDSEDERTIHKTTKLFTRQRSIHSIFGGGKVADILLWREPKIAATLVIGVSILWFLMEVVEYNFITLICHASMTSMLFFFIWSTASDFLNWERPLIPEVVLDESSFKQLARSFHVRFNQILTKLLDVACGRDPPLFFLTTISLYIVSIIGTYFNFVNLLFIGFVSMQTLPVMYEMYEDDVDTAAGKLMRKMKKLYKKVDTNVLSKIPRGTVKNKKFT
What are the official names of this protein?
Reticulon-like protein B9, AtRTNLB9.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: EPIQ_STAEP
Sequence: MISINIVGEVDSILIESILELDRRITINSSNIDPNFIIVYEKFDEYYTFLKEFIGKIPIVIITGNTSYSRKCYFYSLGIDLYIIKNNESKSLILCRILNEIKKYIKYVNDDFIDFENHQFVFNNYLVNLSNIELKILRCLYINLGRYVSKEELKKGVWDTEDFVDSNTINVYIHRLRDSLKNCKEIEIINERKLGYKILIRKDLC
What are the official names of this protein?
Putative epidermin response regulator.
What is the protein family that this protein belongs to?
To the C-terminus of E.coli phosphate regulon transcriptional regulatory protein PhoB.
Protein: TRUB_FRATW
Sequence: MKKNRLNLNGVVVINKAKDISSNKVLQQLKYLFNAQKVGHTGTLDPMATGVLPICFGRATKIAQYLLDADKEYIATIRLGIETDSGDAEGEIIAKSINIPELSAEYLETVLAKFRGDVVQIPPMYSALKYNGQPLYKLAREGKTVEVKSRNIKIYELELLEFNIDSLKIRVKCSKGTYIRSLAIDIGKTLGCGGHLIALQRTQSGPFKLSEAFRLEQLKDLSFEQKIASITNIESVFIDKPIYSLLEEEKDDLYKRGLFADKPHLDGTVRIYDVEKFVAIAEFDKGKLINKKFFDQDILISE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: DHAA_RHOSD
Sequence: MSEIGTGFPFDPHYVEVLGERMHYVDVGPRDGTPVLFLHGNPTSSYLWRNIIPHVAPSHRCIAPDLIGMGKSDKPDLDYFFDDHVRYLDAFIEALGLEEVVLVIHDWGSALGFHWAKRNPERVKGIACMEFIRPIPTWDEWPEFARETFQAFRTADVGRELIIDQNAFIEGVLPKCVVRPLTEVEMDHYREPFLKPVDREPLWRFPNEIPIAGEPANIVALVEAYMNWLHQSPVPKLLFWGTPGVLIPPAEAARLAESLPNCKTVDIGPGLHYLQEDNPDLIGSEIARWLPGLA
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.  Has a broad substrate specificity, which includes primary, secondary and cyclic haloalkanes (chain length > C4).
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
Protein: ISPE_BARHE
Sequence: MISNGQAFFQAPSYLFTPIKLNLALHVVGQRADGYHLIESLVYFSLSGDCLSCTPFGSNRFVLTGPFADELVSDAENLVVRAHDFMCNTFPECAKPAFFQLVKLLPVASGVGGGSGNAAGVLSLLRQQWALDCSCEKLAEMSLVLGADVPMCLFALEYQQPLFVKGIGQDITRLKEACSLAMVLVNHGQQIATKTVFKALEKRDHPPLKIDSAALKTVDSLVEALQETRNDLFVPALKIAPQLSEVLCALDESGALFSRMSGTGATCFGIFKDKQAAQQAALFIKAMYPDWFVKPIVTLAKL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RIC8A_XENTR
Sequence: MDPGTLLDKLESGDQELVQKALAEYNQENSQCFFFNAEQREERKKLGELVIKFLNRDLQPSCQMACLETIRILSRDKHALSPFTGRSAIQTLAQYAGLDYSEEMEMPSIPDGESAVEALKGLCNIIYNSVEAQEVAKELRLVCGLARRLKLYNETRSSHESKFFDLRLLFLLTALSVDMRKQLAQELRGVSLLTDALESTLALKWSDIYEVVTDRLAPPLGKEETERVMEILKTLFNITFDISRREVDEEDAALYRHLAAILRHCLLRQCDGEDRTEEFHGHTVNLLVNLPLMCLDVLLTPKVEQGSVEYMGMNMDTVEVLIQFLDRRLDRGHKLRETLTPVLNLLTESSRVHRETRKFLRAKVLPPLRDVKNRPEVGNTLRNKLVRLMTHVDTDVKHCAAEFLFVLCKENVSRFVKYTGYGNAAGLLAARGLLAGGRGEGRYSEDEDTDTEEYREAKPNINPVTGRVEEKQPNPMDGMTEEQKEYEAMKLVNMFDKLSREQIIQPMGVTSDGRLEPLDEAAQKMLQRQESSDLESDSD
What is the function of this protein?
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.  Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity).
What are the official names of this protein?
Synembryn-A, Protein Ric-8A.
What is the protein family that this protein belongs to?
Belongs to the synembryn family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: ACH1_ARATH
Sequence: MNTESVVEFLGNVTLLQRLPSSSLKRISEVVVFKGYDRGDYVVRENQNVDGVYFLLQGQAQVLRSAGEENYQEFPLKRYDFFGHGIFGDVYSADVVAVTELTCLLLMSDHRALLEIKSVSDSDKERCLVEDILYLEPLDLNVYRGFTPPNAPTYGKVYGGQLVGQALAAASKTVETMKIVHNFHCYFLLVGDINIPIIYDVNRLRDGNNFATRSVDARQKGKTIFTLFASFQKKQQGFIHQESTMPHTPAPETLLPREEMLERLVTEPLLPRDYRNQVATEISVPFPIDIRFCEPNRSTKQNKSPPRLKYWFRAKGKLSDDDQALHRCVVAFASDLIFATISLNPHRREGMSVAALSLDHSMWFHRPVRADDWLLFVIVSPTATESRGFATGKMFNRKGELVVSLTQEAVLREAVTIKPSFGAKL
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (By similarity).  Active with both medium chain and long chain acyl-CoAs as substrates (By similarity).
What are the official names of this protein?
Acyl-CoA hydrolase 1, AtACH1, Acyl-coA thioesterase I, ACT-I, Protein CYCLIC NUCLEOTIDE REGULATED THIOESTERASE 1, AtCNTE1.
What is the protein family that this protein belongs to?
Belongs to the C/M/P thioester hydrolase family.
What are the subcellular locations of this protein?
Peroxisome matrix. Note=Predominantly localized in the peroxisome but a localization to the cytosol cannot be excluded.
Protein: FETA_BOSIN
Sequence: DKNAYGIDLIL
What is the function of this protein?
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.
What are the official names of this protein?
Probable alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: CTAA_BACSU
Sequence: MNKALKALGVLTTFVMLIVLIGGALVTKTGSGQGCGRQWPLCHGRFFPELNPASIIEWSHRFASGISIILVLSLAFWSWRKITPIFRETTFLAIMSIIFLFLQALLGALAVVFGSNALIMALHFGISLISFASVLILTLLIFEADKSVRTLVKPLQIGKKMQFHMIGILIYSYIVVYTGAYVRHTESSLACPNVPLCSPLNNGLPTQFHEWVQMGHRAAALLLFVWIIVAAVHAITSYKDQKQIFWGWISCLIFITLQALSGIMIVYSELALGFALAHSFFIACLFGVLCYFLLLIARFRYESRQS
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.