PharMolix/UniProtQA huggingface dataset:
Protein: RGF1C_MOUSE
Sequence: MPRTLTASDMVTPGSLSPPPTESTEGEQAGQPLLDGAPSSASLDTLIQHLVPTADYYPEKAYIFTFLLSSRLFIEPRELLARVCHLCIEQQQLDKPVLDKARVRKFGAKLLQLLAEWTETFPRDFEEESTIGHLTDVVGRISPCDETYGSRVHQLLQTLHQKLASLGQGPESLVGADKPISYRTKPPASIHRELLGVCSDPYTLAQQLTHVELERLRHIGPEEFVQAFVNKDPLAGTKPRFSDKTNNVEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFFILEHQMDPTGNFCNYRTALRGAAHRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDPSITHYLYTAPIFSEDGLYLASYESESPESQTEKERWKSLRSSILGKT
What is the function of this protein?
Guanine nucleotide exchange factor (GEF).
What are the official names of this protein?
Ras-GEF domain-containing family member 1C.
Protein: MRAZ_CHLPB
Sequence: MAGFIGKEQHSIDEKGRFMIPARFRKLLGDGKEARAKGAIFYVMKAFDGSLELYEPEIWAEKEKGLMSLSDFNPDERMLKTMMYERLDSVEMDRQGRIALPKDFLLHAAIVKDIVIIGANVKMILWSPEKLTSMIRESGTRFQVLAGRYF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL14_RICTY
Sequence: MIQMQSILEVADNSGAKKVMCIKVLGGSHHMMAKLGDVIVVSIKEAIPGGKVKKGDVYKGVIVRTKTGVVRSDGSTIKFDKNALVLLNKQDEPIGTRVFGPVTRELRAKKYVRIMSLAEEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL4_SACD2
Sequence: MELSIATPQGAKGTVSVSEAAFGREFNQDLVHQAVVAFMAGARQGTKAQKNRAAVSGGGKKPWRQKGTGRARAGTIRSPLWRSGGVTFAAEPRDHSQKLNKKMYRAAIRCILSELARQERLVVVEEFDLDAPKTKDLVQKLAQFDLADVLIIGEDVSENLYLAARNLHKVDVRDVNGLDPVSLIRFDKVVVTVAALKKLEEVLV
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: APAG_ANASK
Sequence: MSTAVTEGIEVTVRSTFRPERSEPGRFLFSYTVRIANQGEVPAQLVSRRWIILDANGEREEVVGDGVVGQQPHLEPGEHFEYTSFCVLKTPHGSMRGTYRMVRDGGQAFDATIAPFPLVVPGTLN
What are the official names of this protein?
Protein ApaG.
Protein: TASL_MOUSE
Sequence: MLSEGYLSGLTYWNDIHWNCASYNEPVAGDQGKETSSVAALSYSSVDETQVQSLYVSCKSSGKFISSVHARASQHSRSQSRTVLQANSNPVFESPTLAAVGICRDVIRETYLVPPSCKSICKNYNDLHIAGGQVMAINSVMANFPSESSFEDGPLLKSSEISLSMEDSTSTQLTELPLKPIQRYSSYWRITSIKEKSSLQMQKPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASEFIMTNVDQISLQVSKEKNLDTSKVKDIVISHLLQLVSSEISTPSLHISQYSNITP
What is the function of this protein?
Innate immune adapter that mediates the recruitment and activation of IRF5 downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9.  Following recruitment to endolysosome by SLC15A4 downstream of TLR7, TLR8 and TLR9, specifically recruits IRF5 transcription factor via its pLxIS motif, leading to IRF5 activation and subsequent expression of type I interferons.  Plays a role in the regulation of endolysosomal pH in immune cells such as B-cells, dendritic cells and monocytes.
What are the official names of this protein?
TLR adapter interacting with SLC15A4 on the lysosome.
What are the subcellular locations of this protein?
Lysosome membrane. Endosome membrane. Nucleus. Cytoplasm. Note=Recruited to endolysosome following interaction with SLC15A4. May colocalize with TLR7 in the endosomal pathway.
Protein: PSBI_PHAAO
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL36_BEII9
Sequence: MKVRNSLKSLRTRHRDNRLVRRKGRVYIINKTQKRYKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: COAD_SHIFL
Sequence: MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_STAAE
Sequence: MVKVANKYAKALFDVSLDTNNLETINEELTVINEAVKDKIEQLRMVDSNPTQTAEQRRELINGVFTDINPYIKNMMYVLADNRHISLIADVFKAFQSLYNGHYNQDFATIESTYELSQEELDKIVKLVTQQTKLSKVIVDTKINPDLIGGFRVKVGTTVLDGSVRNDLVQLQRKFRRVN
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CDC73_ARATH
Sequence: MDPLSVLKEFTIRGDIDKIERVGANYRFGSEYSFPCATETAYRSKSGSLYTLEALVHYVKNQQLKHGEYMQSTVKNSVPAVTLPDRKPLLDYLTGRVASSDSIDFLLLQQQNAQSQKQNEEYRPDQDNSAFVSRENAIADMEVEDFGKSGEDVDYIMLIRSNERPLKSRDAILQCKNRDFYSVLVNSTKREEERQRIESHQRKDGLVAKSRLMGAEERGIVGFSSGGGDDNGYDANPKSKLHFKAGKIGEGVPIILVPSAFQTLITIYNVKEFLEDGVYIPNDVKAKEMKGLKPDCITVQKKFSRDRERVVTAYEVRDKPSALKPDDWDRVVAVFVLGKDWQFKDWPFKDHVEIFNKIIGFFLRFEDDSIESAKTVKQWNVKIISISKNKRHQDRAAALEVWEKLEEFVRSRSHS
What is the function of this protein?
Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3) (PubMed:20363855).  Involved in regulation of flowering time.  Required for the expression of the flowering repressors FLC and MADS-box genes of the MAF family.  Required for histone H3 trimethylation on 'Lys-4' (H3K4me3) at the FLC locus (PubMed:20363855, PubMed:20463090).  Prevents trimethylation on 'Lys-27' (H3K27me3) at the same locus (PubMed:20363855).
What are the official names of this protein?
Protein CDC73 homolog, Protein PLANT HOMOLOGOUS TO PARAFIBROMIN.
What is the protein family that this protein belongs to?
Belongs to the CDC73 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCDX_ECOSE
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIAEFADL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: PA2N_GLOHA
Sequence: NLLQFNKMIKEETGKNAIPFYAFYGCYCGGGGQGKPKDGTDRCCFVHDCCYGRLVNCNTKSDIYSYSLKEGYITCGKGTNCEEQICECDRVAAECFRRNLDTYNNGYMFYRDSKCTETSEEC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Neutral phospholipase A2 agkistrodotoxin, AGTX, ATX, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NSP2_ROTSH
Sequence: MAELACFCYPHLENDSYKFIPFNNLAIKAMLTAKVDKKDMDKFYDSIIYGIAPPPQFKKRYNTNDNSRGMNFETIMFTKVAMLICEALNSLKVTQANVSNVLSRVVSIRHLENLVIRKENPQDILFHSKDLLLKSTLIAIGQSKEIETTITAEGGEIVFQNAAFTMWKLTYLEHQLMPILDQNFIEYKVTLNEDKPISDVHVKELVAELRWQYNKFAVITHGKGHYRIVKYSSVANHADRVYATFKSNVKTGVNNDFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKRLLFQKMKPEKNPFKGLSTDRKMDEVSQVGV
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: LOR12_ARATH
Sequence: MELVEETIPKEGKKMGERIVVDKAYLYQEDKPLTVCKTSLFYTGDGFAAYDCRGDIIFRVDSYGPDTRDNDEIVLMDATGKCLLTVKRKRPTLHQRWEGFLGERSEGQKPIFSVRRSSIIGRCTMEVEVYDGTGEEYIIDGDFSQRSCLIYDTKKCTVAEIKRKVDASTNVMLGRDVFTLEIKPGFDGAFAMGLVVVLDQINGDDPVEIGDEQVHPFVED
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 12.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: PRS28_MOUSE
Sequence: MFRLLLLALSCLESTVFMASVSISRSKPVGIVGGQRTPPGKWPWQVSLRMYSYEVNSWVHICGGSIIHPQWILTAAHCIQSQDADPAVYRVQVGEVYLYKEQELLNISRIIIHPDYNDVSKRFDLALMQLTALLVTSTNVSPVSLPKDSSTFDSTDQCWLVGWGNLLQRVPLQPPYQLHEVKIPIQDNKSCKRAYRKKSSDEHKAVAIFDDMLCAGTSGRGPCFGDSGGPLVCWKSNKWIQVGVVSKGIDCSNNLPSIFSRVQSSLAWIHQHIQ
What is the function of this protein?
Involved in embryo hatching and implantation.
What are the official names of this protein?
Serine protease 28, Implantation serine proteinase 1, ISP-1, Strypsin, Tryptase-like proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Note=Secretion into the glandular and uterine lumen may occur as a consequence of progesterone- induced epithelial differentiation.
Protein: MTRC_METTH
Sequence: MSVAAGGPAGAAIPESRLMALGIIGGLGGIYASTVNPVIGPVFASLGAVCAIIWGADAIRRVASYGLGTGVPSIGYMSVSIGIVGVVAGLASVFTLPALAAPVVGLILAMILGVVVAVLGKKIVKMKIPILEKCTAEISGAAALSVLGFSAAIAGSYTMQAVLTSVIATGFIGLLFILNTMAIQHPFNACLGPNENQTRTLKLAASTGFISMAIAGLLGIGLNPGWWLVSLVGALCWVVAFKSFVSASFEEAASVKWSGLWPKEEEQ
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit C, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C.
What is the protein family that this protein belongs to?
Belongs to the MtrC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS21_LEUCK
Sequence: MAKVIVRKNESLDDALRRFKRGVSKDGTLQEYRKREFYVKPSVARKLKSEAAQKRNKKKGR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PROA_STRS2
Sequence: MTTTQVLLDSLLANKASINLATTEQKNQALSAMADQLVAQTEAILAGNAIDMEHAQGKISQVMQDRLLLTEERIEAMADGIRALIGLPDPVGLVLEESTRADGLNICKKSIPFGLVGMIYESRPNVTSDAAALAIKSGNAVILRGGKEAFHSAKAIVTALKSGLEEAGVSPKVIELVQDTSRVSATELMTAKGKIDLLVPRGGAGLIQAVVENATVPVIETGTGICHVYVDKDADLDKALRIVVNAKTSRPSVCNAAEVLLVHEEIASQFLPRLEEALSGQVELRADSQAQALLNQARPAGDQDFDTEFLDYIMAVKVVSSVEEAISHIAQHSTGHSEAIVTENSQTAEHFTLHVDSAAVYVNASTRFTDGGEFGLGCELGISTQKMHARGPMGLREMTTYKYIITGDGHIR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAL1_FUSNN
Sequence: MLENLIKDFKEIFKYSGEVERFFSPGRVNLIGEHTDYNGGFVFPCALDFGTYAVVKKREDKTFKMYSKNFENLGIIEFNLDNLIYDKKDDWANYPKGVIKTFLDRNYKIDSGFDVLFFGNIPNGAGLSSSASIEVLTAVILKDLFKLDVDIIEMVKMCQVAENKFIGVNSGIMDQFAVGMGKKDNAILLDCNTLKYEYVPVKLVNMSIVIANTNKKRGLADSKYNERRTSCEEAVKVLNNNEVNIKYLGELTVTEFEKVKHYITDEEQLKRATHAVTENERAKIAVEFLKKDDIAEFGKLMNKSHTSLRDDYEVTGLELDSLVEAAWEEKGTVGSRMTGAGFGGCTVSIVENDYVDSFIKNVGKKYKEKTGLEASFYIANIGDGAGKVK
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGLU_MUCJA
Sequence: MAKVSFIFVAIALITGNVLCQTDATYAVSSSAPGYKIDGHVRKTEAGLHIPLTLNSRGNKKTGIDTFGKTIKDITVDVEYETEERLHVKISDKAKKQYLVPDSPLGFERPQIKHYVSPKHSNLDFQYTAKPFSFKVVRKDDKTTIFDTTNMPLVFEDQYLELSTKVPEDANIYGIGEVTAPFRRTHNVTTLWARDNPDDFYRNIYGAHPYYQEVRDGKAHGALLMNAHGMDVITTEGRITYKVIGGILDFYFFAPKSGKPNDLSIAYTDLIGKPMMPSHWMLGWHHCRYGYPNIDKVETVKRKYKEANIPLQTVWVDIDYMEETKDFTFDKVNFPQDRMIGLGEQLHKDGQNYVVMVDPAISANTTYEPYVRGTEMDVWIKNADGSDFIGSVWPGFTTFPDWWHPNATKYWNKEIIDFVDMLGVDGLWIDMNEPASFCLGSCGSGKVDAGNQPYRWTYTEEEQAANHTRWEKELKAMGNPPGEERNLLYPKYAINNGAGNLSEFTVATTALHYGNIPHYDIHNLYGHAESHITRQALIKHKNKIRPFVLTRSSFPGSGKSVGHWTGDNHSFWPYLKNSIANILNFQMFGVSYSGADVCGFNSDTTEELCTRWMEIGAFYPFARNHNNNAAKDQEPYLWESTAEASRIAINTRYEMLPYFYTLFEESNRLGLGVWRPLIFEYPAYEELVSNDVQTLVGSDILLSPVLDEGKTSVKAQFPGGQWYDWYTHELTVDNKSNKKVKTVTLDAPLTHIPIHIRGGAIIPTKTPKYTVGETFATPYNLVIALDKKGQASGRLYIDDGESLEVKSSSGYHFHLQEWSPQGFWQVWLQEGRKDWLHHHYWQARQQVAKGSRWQEDYQIDPWQE
What is the function of this protein?
Hydrolyzes not only malto-oligosaccharides but also soluble starch.
What are the official names of this protein?
Alpha-glucosidase, Maltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
Protein: RS17_METRJ
Sequence: MPKRILQGTVVSDKGEKTIVVKVERRFTHPVMKKTVRRSKNYHAHDEGNVAKVGQTVFIEECRPFSKTKTWKLVEGDAAQAEAGEAA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SYM_PSEA6
Sequence: MSSQPRKILVTSALPYANGSIHLGHLLEHIQTDIWTRFQRMCGHEIYSVCADDAHGTPVMLKAQELGITPEEMVARTREEHHQDLLDFFVEYDNYHVTHSDENKELSELIYNRLNDAGYISKRTISQLFDPEKNMFLPDRFVKGTCPSCGAEDQNGDSCDNCGATYDPTEMKNPRSVVSGATPILKDSEHFFFDLPQFSDMLQNWLKSDALQSEISNKLEEWFEKGLQQWDISRDAPYFGFEIPGAPNKFFYVWVDAPVGYMASFKNLCDRSGINFDEYWGADSDAELYHFIGKDITYFHCLFWPAMLEGAGFRKPTGVNVHGFVTVNGAKMSKSKGTFIKGRTYLEHLNPEYLRYYFASKLGANVTDIDLNFEDFAQKVNSDLVGKVVNIASRCASFITKRFDGKLSDNVLEPALVAEFQHAQASIAQAFEERQYHKAIREIMALADKANQFIDANAPWVTIKDESKQAFTHDVCSLGINLFRLLMVYLKPVVPKLAEQAEAFLNDDLSWSSAQSVLTGHEINKFKALMQRVDMDKVNAMVDDSKENLAPTVTLDPNSPLAKDPISDTIEFDDFAKIDLRIAKIVVAEHVEKADKLLRLELDLGGETRQVFAGIKSAYQPEDLVGKLTVMVANLAPRKMRFGMSEGMVLAAGPGGKDLWIMEPHEGAQPGMKVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUTP_STAA9
Sequence: MLTMGTALSQQVDANWQTYIMIAVYFLILIVIGFYGYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLNDKNNVLKIISGLIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVAAMKPTNLNLFKGLSFIGIISLFSWGLGYFGQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGLTGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLIRGEEKAKTHQKEFVMIGRLSVLVVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWKGLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVSVIVTYVVSKLTKKPGAFVETDLNKVRDIVREK
What is the function of this protein?
Catalyzes the sodium-dependent uptake of extracellular L-proline (By similarity).  Since most S. aureus strains are L-proline auxotrophs, this transporter may aid the bacterial persistence during an infection of tissues with low proline concentrations (By similarity).
What are the official names of this protein?
Sodium/proline symporter, Proline permease.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMO_NITEU
Sequence: MTSASSATIQPPRIPRVGFVSLGCPKATVDSERILTCLRAEGYLISPSYADADLVVVNTCGFIDSAVAESLETIGEALTENGKVIVTGCLGAKEDVIRQAHPSVLAVTGPQATEEVMQAIHRHLPKPHDPYLDLVPPQGIKLTPKHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPVGNVLQEAQNLVDAGVRELLIISQDTSAYGVDIKYRTGFWQGRPIRSRITELARALGELGIWIRLHYVYPYPHVDELIPLMAEGKLLPYLDIPFQHGSKRILKLMKRPANSENVLARIRQWRDICPDIALRSTFIVGFPGETEQEFEELLAFLEEAQLDRVGAFAYSPVKGAAANALPDPVPSEIQQERLARLMQWQEEISKKRLAGKKGRILKVLVDTVDENGVIARSYADAPEIDGVVYIEPDFSIKPGDWVDVRITRTGIHDLWAKKI
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMGK_NEIMB
Sequence: MQRQIKLKNWLQTVYPERDFDLTFAAADADFRRYFRATFSDGSSVVCMDAPPDKMSVAPYLKVQKLFDMVNVPQVLHADTDLGFVVLNDLGNTTFLTAMLQEQGETAHKALLLEAIGELVELQKASREGVLPEYDRETMLREINLFPEWFVAKELGRELTFKQRQLWQQTVDTLLPPLLAQPKVYVHRDFIVRNLMLTRGRPGVLDFQDALYGPISYDLVSLLRDAFIEWEEEFVLDLVIRYWEKARAAGLPVPEAFDEFYRWFEWMGVQRHLKVAGIFARLYYRDGKDKYRPEIPRFLNYLRRVSRRYAELAPLYALLVELVGDEELETGFTF
What is the function of this protein?
Sugar kinase that catalyzes the ATP-dependent phosphorylation of N-acetylmuramate (MurNAc) and N-acetylglucosamine (GlcNAc) at its C1 hydroxyl group, leading to MurNAc alpha-1P and GlcNAc alpha-1P, respectively (By similarity).  Is likely involved in peptidoglycan recycling as part of a cell wall recycling pathway that bypasses de novo biosynthesis of the peptidoglycan precursor UDP-MurNAc (PubMed:23831760).  Is able to complement the fosfomycin sensitivity phenotype of a P. putida mutant lacking amgK (PubMed:23831760).
What are the official names of this protein?
N-acetylmuramate/N-acetylglucosamine kinase, MurNAc/GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the kinase AmgK family.
Protein: MRP2_RABIT
Sequence: MLDKFCNSTFWNSSLLDSPEADLPLCFEQTVLVWIPLIFLWLLAPWQLFHVYRSRTKRSPITKFYLAKQVLVGCLLILAVIELILVLTENSGQATIPAVRYTNPILYLVTWLLVLLIQHSRQSCVQKNSWFLSLFWILSILCGTFQFQTLIRTLLRDSNSNLAYSCLFFISYGFQILILILSAFSEKDNSSKNPSVTASFLSKISFSWYDSVVLKGYKRPLTLEDVWDIDEEFKAKTIVSRFEVHMAKELKKARKAFQKRQQKKSQKNSRLQGLNKNQSQSQDVLVLEETKKKNKKSGTTKDFPKSWLVKTIFKTFYMVLLKSFLLKLVYDLLTFLNPQLLKLLITFVSDPNSYAWLGYIFAILLFAVALIQSICLQTYFHMCFNLGMCVGTTVMATVYKKALTISNLAKRQYTIGETVNLMSVDAQKLMDVTNFIHLVWSSVLQIVLSIYFLWVELGPSVLAGVGVMVLLIPVNGILATKNRNIQFKNMKYKDKRLRIMNEILSGMKILKYFAWEPSFKDQVHNLRKKELKNLRTFAYMQSVVMFLLYLTPVLVSVTTFSVYVLVDSNNILDAEKAFTSITLFNILRFPMSMLPNVISAMLQASVSVDRLEKYLSGDDLDTSAIQRDPNFDKAVQFSEASFTWDRNLEPTIRNVNLDIMPGQLVAVVGTVGSGKSSLMSAMLGEMENVHGHITIKGTTAYVPQQSWIQNGTIKDNILFGAEFDERRYQRVLEACALLPDLEILPGGDLAEIGEKGINLSGGQKQRISLARASYQNSDIYILDDPLSAVDAHVGKHIFNKVLGPNGLLNGKTRLLVTHSLHFLPQVDEIVVVENGTILEKGSYSSLLAKKGVFAKNLKMFVKHTDSEGEVTVNDGSEEDDDDDSGLISSIEEFPEDSISLTLKRENSLHRTLSRSSRSSGRRLKSLKNSLKAQNGKTPKEEEVVKGQKLIKKEFMETGKVKFSIYLKYLQAIGWCSIVGIIFAYVLNSVAFIGSNLWLSAWTSDSNTYNGTNYPASQRDLRIGIFGVLGLAQGLTVLVASFWSASGCAHASNILHKQLLNNILRAPMSFFNTTPIGRIVNRFAGDISTVDDTLPQSLRSWMMCFLAIISTLIMICMATPVFAVIIIPLAIIYVAVQVFYVATSRQLRRLDSVTRSPIYSHFTETVSGLPVIRAFEHQQRFLKQNEIGIDTNQKCVSSWITSNRWLAFRLELVGNLVVFSSALMMVIYRDTLSGDVVGFVLSNALNITQTLNWLVRMTSETETNIVAVERITEYIKVENEAPWVTDKRPPAGWPHKGEIQFSNYQVRYRPELDLVLKGINCDIKSMEKIGVVGRTGAGKSSLTNCLFRILEAAGGHITIDGIDIASIGLHDLRGKLTIIPQDPVLFSGSLRMNLDPFNNYSDEEIWRALELAHLKSFVAGLQHGLSREVSEAEDNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDLETDHLIQTTIRNEFSHCTVITIAHRLHTIMDSDKIMVLDNGNIVEYGSPEELLESAGPFSLMAKESGIENVNNTAFWAAAARDAGAGRLSPGFASVT
What is the function of this protein?
ATP-dependent transporter of the ATP-binding cassette (ABC) family that binds and hydrolyzes ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes (PubMed:9614209).  Transports a wide variety of conjugated organic anions such as sulfate-, glucuronide- and glutathione (GSH)-conjugates of endo- and xenobiotics substrates.  Mediates hepatobiliary excretion of mono- and bis-glucuronidated bilirubin molecules and therefore play an important role in bilirubin detoxification (By similarity).  Mediates also hepatobiliary excretion of others glucuronide conjugates such as 17beta-estradiol 17-glucosiduronic acid and leukotriene C4 (PubMed:9614209).  Transports sulfated bile salt such as taurolithocholate sulfate.  Transports various anticancer drugs, such as anthracycline, vinca alkaloid and methotrexate and HIV-drugs such as protease inhibitors (By similarity).
What are the official names of this protein?
ATP-binding cassette sub-family C member 2, Canalicular multidrug resistance protein, Canalicular multispecific organic anion transporter 1, Epithelial basolateral chloride conductance regulator, Multidrug resistance-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.