PharMolix/UniProtQA huggingface dataset:
Protein: NAGB_STRPJ
Sequence: MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYKEIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNAEAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARFFAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNHPDVTIIADAEALSLLEK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RS10_PELTS
Sequence: MKSQKIRIRLKAFDHHMLDQSAQKIVETARRTGASVAGPVPLPTEKSIYTILRSPHVNKDSREQFEMRTHKRLIDILEPNPKTVDALMRLDLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DGT1A_VIBCH
Sequence: MQVSLNPEWLARNNDEHKIRRNDHRSPFQRDRARILHSAAFRRLQAKTQVHGTSLNDFHRTRLTHSLEAAQIGTGIVAQIKLKQPEFRELLPSDSLIDSLCLAHDIGHPPYGHGGEIALNYMMRDHGGFEGNAQTFRIVTSLEPYTEHHGMNLSRRTLLGLLKYPALLSATRAAIPPPAVAHQRQLKAKDWSPAKGIYDCDLASLDWVLEPLCESDRELLGQMRAEPSSPKEHRKTRFKSLDCSIMELADDIAYGVHDLEDAIVLGMVTRAQWQEAAAAQLAECGDPWFEEHIAELSEMLFSGKHYVRKDAIGGIVNALLTSISVKPVEAPFHNELLAFNAYIEPHMGNALEVLKHFVSQYVIQIPQVQRFEYKGQQLIMDLFEALSADPERLLPQATGEKWRKAQEQDEGMRVICDYIAAMTDAYAQRLHQQLFSAQSHY
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: GLCM1_MOUSE
Sequence: MKFFTVLLFVSLAATSLALLPGSKDELQMKTQPTDAIPAAQSTPTSYTSEESTSSKDLSKEPSIFREELISKDNVVIESTKPENQEAQDGLRSGSSQLEETTRPTTSAATTSEENLTKSSQTVEEELGKIIEGFVTGAEDIISGASRITKS
What is the function of this protein?
Adhesion molecule that accomplishes cell binding by presenting carbohydrate(s) to the lectin domain of L-selectin.
What are the official names of this protein?
Glycosylation-dependent cell adhesion molecule 1, GlyCAM-1, Endothelial ligand FOR L-selectin, MC26, SGP50, Sulfated 50 kDa glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the PP3/GlyCAM-1 family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: TRPC_PSEPK
Sequence: MSVPTVLERIIARKFQEVAERSAHVSLAELEGLAKAADAPRGFANALIEQAKRKQPAVIAEIKKASPSKGVIREHFVPAEIAVSYEKGGATCLSVLTDVDYFQGADEYLQQARAAVSLPVIRKDFMVDPYQIVEARALGADCVLLIVSALDDVKMAELAATAKDVGLDVLVEVHDGDELERALKTLDTPLVGVNNRNLHTFEVSLETTLDLLPRIPRDRLAITESGILNRADVELMAINEVYSFLVGEAFMRAEQPGLELQRLFFPEQVKKTVQQLD
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RECA_AZOVI
Sequence: MDENKKRALAAALGQIEKQFGKGAVMRMGDHERQAIPAISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSTIAEAQKQGATCAFVDAEHALDPDYAAKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDQHVGLQARLMSQALRKITGNIQNANCLVIFINQIRMKIGVMFGNPETTTGANALKFYASVRLDIRRTGAVKESDEVIGSETRVKVVKNKVAPPFRQAEFQILYGKGIYRNGEIIDLGVQLGLLEKSGAWYSYQGSKIGQGKANAAKFLEDNPEVAAAVEKSIRDQLLAAPASARPAALADEPADADLDY
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPH1_ASPOR
Sequence: MTGSDDSSVDYFREGFDDITDDEFPDATRNAVGSSPRPAKRRRRDGTASDVRRRPSENRESQRYSDGGSPQTGSDSFVVDDDEGNYDELQSPSQDSYFEDAEAPSKYKVFIPKRSNIQENIFVTQLTQPPSPPEMIRGPRWKKPEPSIARASTIPTQTIGEGRAAPNAPAASVDDYDDEDLNAAIAASLESFENEQSRPPPSNTKAPTHQPITRSPTVQNEGATDTSFLLEDIPDDAFDSDISLSPPTRAQQQPATRQFGQSSNRPLGVRQTSLFDMTSRNQTDQPPIGEQVWSPPQKDEPPTQHKLDHDALSTWVYPTNLGKTRDYQFNIAQKGLFHNLLVALPTGLGKTFIAATIMLNWFRWTESAQIIFVAPTKPLVAQQISACFGIAGIPRSQTTMLTGEAAPGIRAEEWQNKRVFFMTPQTLINDLKSGIADPKRIVLLVVDEAHRATGGYAYVEVVKFLRRYNQSFRVLALTATPGSTVESVQAVIDGLDIARVEIRTEQSLDIREYVHSRNTEVQTFKNSEEMVLCMDLLSKTLQPLVDQLRTLNAYWGRDPMMLTAFGLTKSRQQWMASDAGRNAHFGLKGKVNAIFTVLASLAHAIDLLKYHGITPFYRHLLHFQSNTEGQKGGKYQRQVVQDESFKKLINHLQPWTKNPEFIGHPKLEYLKSVVLNHFMDAGEGSNGEASDSQSSTRIMIFVHFRDSAEEVTRVLKRYEPMIRPHVFVGQSSAKGSEGMGQKTQLDIVQKFKKGTYNTIVATSIGEEGLDIGEVDLIVCYDSSASPIRMLQRMGRTGRKRAGNIVLLLMEGKEEESYIKAKDNYEKMQQMIASGSRFTFHDDISPRILPAGIRPVADKRHIDIPDENAEQSLPEPKRRGRAPKRPPKKFHMPDNVETGFTKASSLTAGPKSKAEKSRKPRTPTPEPVEIPALEEVVLTSAQQRELEQHYRNIGAASPQFIRNPRNDAFPRLQLVARPTKVVKHGSLTRRMIGTLQKMNNVGPDCGDRFKKILALESARQGDSVIPNRSPRHERRRRLSKTKPRYNHLSTSVDKETLSTEDSQLVTPEHLLSSVVKGQKQQPFYSSQRSKDDDSDDNFDPPDLATLLTRSAERNNAHKTSRFVVSDDSDD
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops.  Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair.  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
What are the official names of this protein?
ATP-dependent DNA helicase mph1, FANCM-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMH_MESHJ
Sequence: MKISIISFGSSPREWLGLYKKEINKIKQFKYQIEFINLSEHSQENIELKKMLETKDILQKIPKNSSCYLFTERGKTVTSKEFSQLLNFSNICFIIGGSYGVDEKLIAKSRPDIGFLSFGKLTFAHKIFKLIVLEQIYRGFSIKFNRKYHHAD
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHS3_MEDSA
Sequence: MVSVSEIRQAQRAEGPATIMAIGTANPSNCVEQSTYPDFYFKITNSEHKVELKEKFQRMCDKSMIKRRYMYLTEEILKENPSVCEYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPSDTHLDSLVGQALFGDGAAALIVGSDPIPEIEKPIFEMVWTAQTIAPDSEGAIDGHLVEAGLTFHLLKDVPGIVSKNIDKALIEAFQPLNISDYNSIFWIAHPGGPAILDQVEEKLGLKPEKMKATREVLSEYGNMSSACVLFILDEMRKKSAQAGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAI
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 4-1, Naringenin-chalcone synthase 4-1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: MRX3_YEAST
Sequence: MSRTIPFLFKLVNRAVILPTAGFTLGVGAFVKAWPDDAGVLSLNDPQTPAELISATKSRQPMELQRVDILAQIEKSEVYNKLAQDEKMHHVLFSEKIPSGHREYHVGQGLLFGKGKLEIDPLVFHDVNHGELTVIYHLGAELGNRDGNVHKGLLSLLLDEALCYCGFPLLPSKRGVTARLSLEFFEDIPVDTTIILKANVKEIKGRKCIIEGHLEQFPLEVSSRNGTRSWNLPHIWGFNHKQEMAKKFAKANCILVEPTWFKYFKWLDMF
What is the function of this protein?
Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression.
What are the official names of this protein?
MIOREX complex component 3, Mitochondrial organization of gene expression protein 3.
Protein: FLIF_BACSU
Sequence: MNRTLMQMKNKTSEFWKNRSKLQKILMVSALAAIIIIGIIISVFASNSKMAPLYKDLSAEEAGQIKEELDAKKVPNELSNGGTVISVPEDQVDSLKVQMAAEGLPKTGSIDYSFFGQNAGFGLTDNEFDMVKVKATQTELSNLINEMDGIKNSKVMINLPKDAVFVGEEQSAASASIVLQIQPGYTLDQSQINGLYHLVSKSVPNLKEDNIVIMDQNSTYYDKSDSDAGSYADSYSSQQGIKSQVEKDIQKHVQSLLGTMMGQDKVVVSVTADIDFTKENRTEDIVEPVDKENMEGIAVSAEKVSETYQGDGAANGGTAGTGEEDVTNYKADGENTESGNYEKNSNKINYEVNRIHKEIAESPYKVRDLGIQVMVEPPDAKNTASLSTERQDDIQKILSTVVRTSLDKDETQNQNLSDADINNKIVVSVQPFDGKVNLDTNTEESSGIPLWAYIVGGVLIAAIIVLIIMLIRKKRAQEDEFEEYEYEVPQEPINLPDINEEENETAESVRRKQLEKMAKDKPEDFAKLLRSWLAED
What is the function of this protein?
The M ring may be actively involved in energy transduction.
What are the official names of this protein?
Flagellar M-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FliF family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: PSIE_ECOUT
Sequence: MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLADVLFAPEQASKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLIIVDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VP3_SSV2
Sequence: MEELNIKQILFLAIFLVIGVVLFQPIISYVNNVTTSGTYTTIISGTLTQTSFVSNPNYVGSSNAPLVSLVPLFYLIVLIVVPAVVAYKIYKD
What are the official names of this protein?
Structural protein VP3.
What is the protein family that this protein belongs to?
Belongs to the fuselloviridae capsid protein VP1/VP3 family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein.
Protein: ECR_MANSE
Sequence: MRRRWSNNGCFPLRMFEESSSEVTSSSAFGMPAAMVMSPESLASPEYGGLELWSYDETMTNYPAQSLLGACNAPQQQQQQQQQQPSAQPLPSMPLPMPPTTPKSENESMSSGREELSPASSINGCSTDGEPRRQKKGPAPRQQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAVYICKFGHACEMDMYMRRKCQECRLKKCLAVGMRPECVVPESTCKNKRREKEAQREKDKLPVSTTTVDDHMPAIMQCDPPPPEAARIHEVVPRFLTEKLMEQNRLKNVTPLSANQKSLIARLVWYQEGYEQPSEEDLKRVTQTWQLEEEEEEETDMPFRQITEMTILTVQLIVEFAKGLPGFSKISQSDQITLLKASSSEVMMLRVARRYDAATDSVLFANNQAYTRDNYRKAGMSYVIEDLLHFCRCMYSMSMDNVHYALLTAIVIFSDRPGLEQPLLVEEIQRYYLKTLRVYILNQHSASPRCAVLFGKILGVLTELRTLGTQNSNMCISLKLKNRKLPPFLEEIWDVAEVSTTQPTPGVAAQVTPIVVDNPAAL
What is the function of this protein?
Receptor for ecdysone.  Binds to ecdysone response elements (ECRES).
What are the official names of this protein?
Ecdysone receptor, 20-hydroxy-ecdysone receptor, 20E receptor, EcRH, Ecdysteroid receptor, Nuclear receptor subfamily 1 group H member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KIN1_SCHPO
Sequence: MEYRTNNVPVGNETKSAALNALPKIKISDSPNRHHNLVDAFMQSPSYSTQPKSAVEPLGLSFSPGYISPSSQSPHHGPVRSPSSRKPLPASPSRTRDHSLRVPVSGHSYSADEKPRERRKVIGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNKEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYPSYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWMIRNYEGPPASFAPERSPITLPLDPEIIREMNGFDFGPPEKIVRELTKVISSEAYQSLAKTGFYSGPNSADKKKSFFEFRIRHAAHDIENPILPSLSMNTDIYDAFHPLISIYYLVSERRVYEKGGNWNRIAKTPVSSVPSSPVQPTSYNRTLPPMPEVVAYKGDEESPRVSRNTSLARRKPLPDTESHSPSPSATSSIKKNPSSIFRRFSSRRKQNKSSTSTLQISAPLETSQSPPTPRTKPSHKPPVSYKNKLVTQSAIGRSTSVREGRYAGISSQMDSLNMDSTGPSASNMANAPPSVRNNRVLNPRGASLGHGRMSTSTTNRQKQILNETMGNPVDKNSTSPSKSTDKLDPIKPVFLKGLFSVSTTSTKSTESIQRDLIRVMGMLDIEYKEIKGGYACLYKPQGIRTPTKSTSVHTRRKPSYGSNSTTDSYGSVPDTVPLDDNGESPASNLAFEIYIVKVPILSLRGVSFHRISGNSWQYKTLASRILNELKL
What is the function of this protein?
Has a role in establishing the characteristic rod cell shape.  Important for cell polarity and is involved in directing growth to the cell ends.
What are the official names of this protein?
Protein kinase kin1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized to the cell tips except during mitosis.
Protein: CLD1_BOVIN
Sequence: MANAGLQLLGFILAFLGWIGSIVSTALPQWKVYSYASDNIVTAQAIYEGLWMSCVSQSTGQIQCKVFDSLLNLNSTLQATRALMVIGILLGLIAIFVATVGMKCMKCMEDDEAQKMRMAVFGGVIFLISGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFIGWAAASLCLLGGALLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
What is the function of this protein?
Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia.  While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules.  Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability.  CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin.  Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (By similarity).
What are the official names of this protein?
Claudin-1.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Basolateral cell membrane. Note=Associates with CD81 and the CLDN1-CD81 complex localizes to the basolateral cell membrane.
Protein: RNPH_PARMW
Sequence: MPAPTPKRADGRGATELRPFSVDWDPMSFALSSLIVRTGRTAVLCSVSLEEDVPRWRRGNGCGWLSAEYRLLPGSTPQRQSRELMKLSGRTQEIQRLIGRSLRAVLDMDALGERTLLIDCDVIQADAGTRTASITGAWIALRRACDLLRSQGVLTQDPIRQQLAAVSVGLIDGTPLLDLDYSEDSRADVDLNVVTAGDGRLLELQGTAEQAPFSRSELDAMLNLAESGLQELMQGQRHALATAAGSAIS
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: SELO_ECOL6
Sequence: MTLSFITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIPSSLFKNGAGVWGGENLLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETVESGAMLMRVAPSHLRFGHFEHFYYRREPEKVRQLADFAIRHYWSHLDDEEDKYRLWFTDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSDHQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGQRMRQKLGFMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDWFARYRGRLQQDEITDSERQQLMQSVNPALVLRNWLAQRAIEAAEKDDMTELHRLHEALRNPFSDRDDDYVSRPPDWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: PDGFC_HUMAN
Sequence: MSLFGLLLLTSALAGQRQGTQAESNLSSKFQFSSNKEQNGVQDPQHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPSVLPPSALPLDLLNNAITAFSTLEDLIRYLEPERWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNLLTEEVRLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSKVTKKYHEVLQLRPKTGVRGLHKSLTDVALEHHEECDCVCRGSTGG
What is the function of this protein?
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.  Potent mitogen and chemoattractant for cells of mesenchymal origin.  Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate.  Required for normal skin morphogenesis during embryonic development.  Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling.  Plays an important role in angiogenesis and blood vessel development.  Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs.  The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain.  In the nucleus, PDGFC seems to have additional function.
What are the official names of this protein?
Platelet-derived growth factor C, PDGF-C, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Secreted. Nucleus. Cytoplasmic granule. Cell membrane. Note=Sumoylated form is predominant in the nucleus (PubMed:15247255). Stored in alpha granules in platelets (PubMed:15061151).
Protein: ISCS_PHOPR
Sequence: MKLPIYFDYSATCPVDPRVAEKMMQCLTMDGNFGNPASRSHRFGWQAEEAVDTAREQVADLMNADPREIVFTSGATESDNLAIKGAARFYSKKGKHIITCKTEHKAVLDPCRQLEREGFEVTYLDPEANGLIDMAKLRDAIREDTVLMSIMHVNNEIGVIQDITAIGELCRENKIVFHVDAAQSIGKLPIDVQAMKVDLISVTSHKIYGPKGIGALYVRRKPRIRLEAQMHGGGHERGMRSGTLATHQIVGMGEAFRIAKEEMEQDRVHTLALRTRLLDGLKDMESVHINGDLEQRVSSNLNISFAFVEGESLLMALKDLAVSSGSACTSASLEPSYVLRALGLDDELAHSSIRFSFGRFSTEEEIDYAITQIRTAVEKLRDMSPLWDMHKEGIDLNSVEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUS4_YEAST
Sequence: MHTMHIPSGDVLIPKPKLITEETDPLHIIKTRQKTHGRPVTIAGPMVRYSKLPFRQLCREYNVDIVYSPMILAREYVRNEHARISDLSTNNEDTPLIVQVGVNNVADLLKFVEMVAPYCDGIGINCGCPIKEQIREGIGCALIYNSDLLCSMVHAVKDKYGDKLRIETKIRIHEALDETVELCRKLCDAGVDWITIHGRTRRTRSSQPANLDAIKYIIENISDKNVPVIANGDCFKLSDLERITKYTGAHGVMAVRGLLSNPALFAGYTTCPWGCIEKFCYWALEFGGLPFQLAQHHLYCMLENMELKKSLLKKMMNLKNYISLIDWFNKTFEFKRYGEDGFGMGVEIPYKANSCVQRSASVVERQE
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:14970222).  Specifically modifies U20a and U20b in cytoplasmic tRNAs (PubMed:14970222).  Also able to mediate dihydrouridylation of some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+], mRNA-dihydrouridine synthase DUS4, tRNA-dihydrouridine synthase 4.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus4 subfamily.
Protein: TFB5_CANAL
Sequence: MLVASKGVLVQCDPSIKALIIQIDSSSSGIILEELDETHLLIQHDKVNFVKSELNRLLSKNIYNPFEEE
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH subunit TFB5, TFIIH subunit TFB5, RNA polymerase II transcription factor B subunit 5.
What is the protein family that this protein belongs to?
Belongs to the TFB5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPG_TRYBB
Sequence: MSGKLRLYKEKLEGYNRFYSIVKTIKMVTLAKYRAAQGRIRTRDFSLRYTELAFSKPQASRDAVAAAKNALVYIPITTNRGSCGALNSNIVRCIDSVVSSKMVLMPVGKRGIDSFSKLYPDEFRYGIINDMKESMHFGYATFVIENAYEVSKDADRYQVIFNRFVSAGVQRNAVYNIPSYEKWKEDLADAASSDNQKNRYLFANALQNEEEQLIRDFFDFHAALAVLNAVGENELSEQAARLVAVEGQLTNISSLQQRTSSLYNKTRQFGITAALIEILSAMSSLEGNAMKGVRRNKFWEGAVTK
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(o) ATP synthase) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:19436713, PubMed:29247468).  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(o) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:19436713, PubMed:29247468, PubMed:29440423).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1) (PubMed:19436713, PubMed:29440423).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits (Probable).  Contrary to the procyclic, insect form that requires F(1)F(o) ATP synthase for ATP synthesis, the bloodstream form relies on ATP hydrolysis by F(1)F(o) ATP synthase to maintain its mitochondrial membrane potential (PubMed:29247468).
What are the official names of this protein?
ATP synthase subunit gamma, mitochondrial, ATP synthase F1 subunit gamma, F(1)F(o)-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: APE3_YEAST
Sequence: MHFSLKQLAVAAFYATNLGSAYVIPQFFQEAFQQEEPIENYLPQLNDDDSSAVAANIPKPHIPYFMKPHVESEKLQDKIKVDDLNATAWDLYRLANYSTPDYGHPTRVIGSKGHNKTMEYILNVFDDMQDYYDVSLQEFEALSGKIISFNLSDAETGKSFANTTAFALSPPVDGFVGKLVEIPNLGCEEKDYASVVPPRHNEKQIALIERGKCPFGDKSNLAGKFGFTAVVIYDNEPKSKEGLHGTLGEPTKHTVATVGVPYKVGKKLIANIALNIDYSLYFAMDSYVEFIKTQNIIADTKHGDPDNIVALGAHSDSVEEGPGINDDGSGTISLLNVAKQLTHFKINNKVRFAWWAAEEEGLLGSNFYAYNLTKEENSKIRVFMDYDMMASPNYEYEIYDANNKENPKGSEELKNLYVDYYKAHHLNYTLVPFDGRSDYVGFINNGIPAGGIATGAEKNNVNNGKVLDRCYHQLCDDVSNLSWDAFITNTKLIAHSVATYADSFEGFPKRETQKHKEVDILNAQQPQFKYRADFLII
What are the official names of this protein?
Aminopeptidase Y.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28A subfamily.
What are the subcellular locations of this protein?
Vacuole. Note=Lysosome-like vacuoles.
Protein: RS4_KORCO
Sequence: MGDIRKHRKKYERPYKPWDRRVLEETNRLAGYYGLRNKRELWRMSFLAKKYRRIARQLLAAPKSESWKVEPIIKKLQALGILSKDATLDDLLDLSVEQFLERRLQTIVWRKGFAKSPYMARQLITHGHIRVNGRRIRQPSYLVKIEEEDKIECLHPSCLEVEKEVR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.