PharMolix/UniProtQA huggingface dataset:
Protein: KCAB3_MOUSE
Sequence: MSRGYGLIFSLKVVFTFLSLPHPPGLQGSLDRLQLEYVDIVFANRSDPNSPMEEIVRAMTYVINQGLALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACGLITSKYDGRVPDTCKATVKGYQWLKEKVQSEEGKKQQARVMDLLPTARQLGCTVGQLAIAWCLRSEGVSSVLLGVSSAEQLMEHLGSLQVLSQLTPQTVVEIDALLGNKSHSKK
What is the function of this protein?
Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.  Alters the functional properties of Kv2. 2 but not Kv2. 1.
What are the official names of this protein?
Voltage-gated potassium channel subunit beta-3, K(+) channel subunit beta-3, Kv-beta-3.
What is the protein family that this protein belongs to?
Belongs to the shaker potassium channel beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCG5_RAT
Sequence: MSTCGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGIILPQNQSTEVKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNSQMTSESTVNVLKMIRSATPFPLVSLFFMFIGFILSNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWIRGRSPSDISSDASLQMNSNYPALLKCPDYDQMSSSPC
What is the function of this protein?
Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs).  Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization.  Displays subunit-specific AMPA receptor regulation.  Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2.  According to PubMed:18817736, shows only specificity for GRIA2 and specifically to the form of GRIA2 for which a single amino acid in the pore region has been edited from a glutamine to an arginine residue.  Thought to stabilize the calcium channel in an inactivated (closed) state.
What are the official names of this protein?
Voltage-dependent calcium channel gamma-5 subunit, Neuronal voltage-gated calcium channel gamma-5 subunit, Transmembrane AMPAR regulatory protein gamma-5, TARP gamma-5.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Postsynaptic density membrane.
Protein: GPDA_STRPZ
Sequence: MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKDIEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIERNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSENEWH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_CUPMC
Sequence: MTQQANQTVATISAEALRQSARNIAAAAPKEGDAWRVDDVAALFALPFNDLLFRAQQVHREHFDANTVQLSTLLSIKTGGCEEDCGYCPQSAHHDAGVKAEKLMDLEAVLDAAKAAKANGATRFCMGAAWREPKERHLEPVIDMVREVKAMGLETCVTLGMLKAEQAQRLKDAGLDYYNHNLDTSPEFYGKIITTRTYQDRLDTIGHVREAGINVCCGGIVGMGEAREARAGLIAQLANMDPYPESVPINNLVQVEGTPLAGTEALDPFEFVRTIAVARITMPRAMVRLSAGREAMDEALQALCFMAGANSIFYGEKLLTTGNPQADRDRALLARLDIRAEGYAG
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ZRAS_SALTI
Sequence: MSFIRLHKDAAAMWLSRLLPAAIFILVGLFSIMVIRDYGRESAAARQTLLEKGNVLIRALESGTRVGMGMRMHHAQQQTLLEEMAGQPGVLWFAVTDAQGVIITHSNPGMVGKSLYSPSEMHQLNPGPQECWRRVDVAANGETVPALEIYRQFQPLFGMRGHGMRGHGMARSANDDEPAKQTIFIAFDASELAATQAREWRNTLIVLSALAAVLLATLLAFFWYQRYQRSHRELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPAGGESHELAQVMAKEADRLNRVVSELLELVKPAHLTLQAVNLNDIITHSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTITVEAKESGTDRVIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPVIARQQD
What is the function of this protein?
Member of the two-component regulatory system ZraS/ZraR.  May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium (By similarity).
What are the official names of this protein?
Sensor protein ZraS.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLEB_HALH5
Sequence: MSTRGWLKIPLLSLALFLSLMSMTTTAHAFSDQVIQHGATGDDVVELQARLQYIGFYNKKIDGVFGWSTYWAVRNYQYEFGMEVDGLVGPEMKAKLEKTTNFNRDFVDRALTQGRKFTHYGGVPKQIQKGPKGSADERRRGREGVRQPRADRPGRDAPAAPRDERAPRREERPAPTPEPTPAPPEEPTPYEEAPDAQDDEANIEKATNVPAGYSDNDIQLMAQAVYGEARGEPYVGQVAVAAVILNRLNSPTFPDNVSGVIFEPLAFTAVADGQIYMTPDETARRAVLDALNGQDPSGGATYYFNPDTATSGWIWSRPQIKRIGKHIFCN
What is the function of this protein?
Required for spore cortex hydrolysis during germination.
What are the official names of this protein?
Spore cortex-lytic enzyme, SCLE.
What is the protein family that this protein belongs to?
Belongs to the SleB family.
Protein: LGOX_STRSQ
Sequence: MTTDTARRHTGAERANEMTYEQLARELLLVGPAPTNEDLKLRYLDVLIDNGLNPPGPPKRILIVGAGIAGLVAGDLLTRAGHDVTILEANANRVGGRIKTFHAKKGEPSPFADPAQYAEAGAMRLPSFHPLTLALIDKLGLKRRLFFNVDIDPQTGNQDAPVPPVFYKSFKDGKTWTNGAPSPEFKEPDKRNHTWIRTNREQVRRAQYATDPSSINEGFHLTGCETRLTVSDMVNQALEPVRDYYSVKQDDGTRVNKPFKEWLAGWADVVRDFDGYSMGRFLREYAEFSDEAVEAIGTIENMTSRLHLAFFHSFLGRSDIDPRATYWEIEGGSRMLPETLAKDLRDQIVMGQRMVRLEYYDPGRDGHHGELTGPGGPAVAIQTVPEGEPYAATQTWTGDLAIVTIPFSSLRFVKVTPPFSYKKRRAVIETHYDQATKVLLEFSRRWWEFTEADWKRELDAIAPGLYDYYQQWGEDDAEAALALPQSVRNLPTGLLGAHPSVDESRIGEEQVEYYRNSELRGGVRPATNAYGGGSTTDNPNRFMYYPSHPVPGTQGGVVLAAYSWSDDAARWDSFDDAERYGYALENLQSVHGRRIEVFYTGAGQTQSWLRDPYACGEAAVYTPHQMTAFHLDVVRPEGPVYFAGEHVSLKHAWIEGAVETAVRAAIAVNEAPVGDTGVTAAAGRRGAAAATEPMREEALTS
What is the function of this protein?
Catalyzes the oxidative deamination of L-glutamate to 2-ketoglutarate along with the production of ammonia and hydrogen peroxide (Ref. 2, PubMed:14769868, PubMed:22197816).  Shows strict substrate specificity for L-glutamate, and exhibits only very weak activity with L-aspartate (Ref. 2).
What are the official names of this protein?
L-glutamate oxidase precursor, LGOX.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. LGOX subfamily.
Protein: RLME_METB6
Sequence: MGSQWSRDKVYLRAKHEGFRSRASYKLIEIQEKFAVIRRDDNIIDLGAAPGSWLQVLRTLTDGRVLGIDLNPIADIEGIETLEGDLTDPVVQKQAKEMLGTVCIVVCDAAPKLSGHKSYDQARAIALGEEALLFACNVLKPGGNFVIKSFQGADFPELLAAIQGQFYAVKTYSTKATRKGSTEIYIIAKNFKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_THEVB
Sequence: MVSIRPDEISSIIRQQIEQYEQSIKVDNVGTVLQVGDGIARVYGLDKVMASELVEFEDGTVGIALNLEEDNVGVVLMGDGLSIEEGSTVRATGKIASIPVGEAAIGRVVDALMRPIDGKGEIHTTQSRLIESPAPGIVQRKSVCEPLQTGITAIDAMIPIGRGQRELIIGDRQTGKTAVAIDTILNQKGQDVICVYVAIGQKASSVAQVVNVLRERGALDYTIVIAANASDPAALQYLAPYTGATVAEYFMYQGKHTLVVYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDALGGGSMTALPVVETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGLRPAINAGISVSRVGSAAQIKAMKQVAGKLKLELAQFDELQAFAQFASDLDKATQNQLARGQRLREILKQPQYSPIPVEYQVATIYAGTNGYLDDIPVEAVAKFVAGLRDYLRTNKPEYGEIIRTTQKLDEKAEALLKEAIAEYKATFTA
What is the function of this protein?
The complex from the organism is particularly stable to disruption and remains functional after 6 hrs at 55 degrees Celsius.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: BETB_RHILO
Sequence: MRAQPTASHYVNGRYIDDEQGAPLPVIYPATGETIAMLRSATPNVLELAIEAARAAQPAWARLKPVERGRILRRAADILRARNADLARIETLDTGKAIQETLVADAPSAADCLEYFGGAVAAYNGEAVDLGGPFAYTRREALGVCVGIGAWNYPIQIAGWKSAPALAMGNAMVFKPSENTPLSALALAEIYSEAGLPDGLFNVVQGYGDVGAGLVGHDVVAKVSVTGSVPTGRKVLSLAGSKMKHATMELGGKSPLIVFDDADIENAIGGAMLGNFYSTGQICSNGTRVFVQSGIHDRFVERLVERTKKIRIGNPLDPETQMGPLVSKAQHEKVVGYIGIGKQDGAVLACGGNVPSLQGFDGGFFVEPTVFTGVTDTMRIAREEIFGPVMSVLKFDGEDEVIDRANDTEFGLAAGVFTRDLPRAHRVIAELQAGTCWINAYNLTPVEIPFGGFKQSGIGRENSLAALALYSQLKSIYVETGDVASPY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: CRYL1_RABIT
Sequence: MASPAAGDVLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALENIRKEMKSLQQSGSLKGSLSAEEQLSLISSCTNLAEAVEGVVHIQECVPENLDLKRKIFAQLDSIVDDRVVLSSSSSCLLPSKLFTGLAHVKQCIVAHPVNPPYYIPLVELVPHPETSPATVDRTHALMRKIGQSPVRVLKEIDGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSDGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGMKRVLKSFGSIPEFSGATVEKVNQAMCKKVPADPEHLAARREWRDECLKRLAKLKRQMQPQ
What is the function of this protein?
Functions as crystallin in the rabbit eye lens.  Has high L-gulonate 3-dehydrogenase activity.  It also exhibits low dehydrogenase activity toward L-3-hydroxybutyrate (HBA) and L-threonate.
What are the official names of this protein?
Lambda-crystallin, L-gulonate 3-dehydrogenase, Gul3DH.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAF_RAT
Sequence: MTTSQKHRDFVAEPMGEKPVGSLAGIGDALGKRLEERGFDKAYVVLGQFLVLKKDEDLFREWLKDTCGANAKQSRDCFGCLREWCDAFL
What is the function of this protein?
Non-specific DNA-binding protein that plays key roles in mitotic nuclear reassembly, chromatin organization, DNA damage response, gene expression and intrinsic immunity against foreign DNA.  Contains two non-specific double-stranded DNA (dsDNA)-binding sites which promote DNA cross-bridging.  Plays a key role in nuclear membrane reformation at the end of mitosis by driving formation of a single nucleus in a spindle-independent manner.  Transiently cross-bridges anaphase chromosomes via its ability to bridge distant DNA sites, leading to the formation of a dense chromatin network at the chromosome ensemble surface that limits membranes to the surface.  Also acts as a negative regulator of innate immune activation by restricting CGAS activity toward self-DNA upon acute loss of nuclear membrane integrity.  Outcompetes CGAS for DNA-binding, thereby preventing CGAS activation and subsequent damaging autoinflammatory responses.  Also involved in DNA damage response: interacts with PARP1 in response to oxidative stress, thereby inhibiting the ADP-ribosyltransferase activity of PARP1.  Involved in the recognition of exogenous dsDNA in the cytosol: associates with exogenous dsDNA immediately after its appearance in the cytosol at endosome breakdown and is required to avoid autophagy.
What are the official names of this protein?
Barrier-to-autointegration factor, LAP2-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the BAF family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Nucleus envelope. Cytoplasm. Note=Significantly enriched at the nuclear inner membrane, diffusely throughout the nucleus during interphase and concentrated at the chromosomes during the M-phase. The phosphorylated form (by VRK1) shows a cytoplasmic localization whereas the unphosphorylated form locates almost exclusively in the nucleus. May be included in HIV-1 virions via its interaction with viral GAG polyprotein.
Protein: IPO11_MOUSE
Sequence: MDLNSASSVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLVESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQHVSSGNEAAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDNVCRDRLEKTIILFTKVLLDFLDQHPISFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQCMNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLEGPTNVEDMNALLIKDAVYNAVGLAAFELFDSVDFDQWFKTQLLPELQVSHNRYKPLRRRVIWLIGQWISVKFKSDLRPMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVLSCVIERVNVQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCVTPELLRIFQNMSPLLELSSENLRTCFKIINGYIFLSSTEFLQTYAAGLCQSFYELLPEITTEGQVQVLKVVENALKVNPVLGPQMFQRILPCVFRGVIEGERYPVVMSIYLAVMGRVLLQNTSFFSSLLNEMGHEFNQEMDQLLGNVIEMWVDRMDNITQPERKKLSALALLSLLPSDNSVIQDKFCGIINISVEALHDVMTEDPETRTYKDCMLMSQHEEPKVTEDEEPPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEILGEQGFQSLMETVDTEIVTQLQEFLQGF
What is the function of this protein?
Functions in nuclear protein import as nuclear transport receptor.  Serves as receptor for nuclear localization signals (NLS) in cargo substrates.  Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).  Mediates the nuclear import of RPL12, and of UBE2E3 (By similarity).
What are the official names of this protein?
Importin-11, Imp11, Ran-binding protein 11, RanBP11.
What is the protein family that this protein belongs to?
Belongs to the importin beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RNH2_NEIG1
Sequence: MHILTAGVDEAGRGPLVGSVFAAAVILPETFDLPGLTDSKKLSEKKRDALAEMIKEQAVAWHVAASTPEEIASLNILHATMLAMKRAVYGLAARPEKIFIDGNRIPEHLGIPAEAVVKGDSKIIEISAASVLAKTARDAEMYALAQRRPQYGFDKHKGYGTKQHLEALKQYGVLPEHRRDFAPVRNLLAQQALF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWP05_TOBAC
Sequence: VPPAVWNSXNYNS
What are the official names of this protein?
66 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: YHEU_SALTI
Sequence: MIIPWQGLAPDTLDNLIESFVLREGTDYGEHERSLEQKVADVKRQLQSGEAVLVWSELHETVNIMPKKQFRE
What are the official names of this protein?
UPF0270 protein YheU.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: HIS1_CALS4
Sequence: MDIVSIALPKGRMTEDAVVLFKKAGISNDVLKDISRKLILEDNKNAIKFMLVKPMDVPTYVEHGAADLGVCGKDILLEQKKDLYEVLDLKFGFCRMVVAGPPNVKDSFLTNKRVATKFPNVAEEFFKKKGENVEIIKLNGSVELAPIVGLSEVIVDIVETGRTLRENGLVVIEEIFPSTARLIVNKASMKTKSERIKDIILKLREVINGG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYCC1_ARATH
Sequence: MSEMEVEKPDLTLYNTMTQLKEVYKPMNPGKIGIYVCGITAYDYSHIGHARAAVSFDLLYRYLRHLGYQVTYVRNFTDVDDKAKNCGEKPLDLSNRFCEEYLLDMAALQCLLPTHQPRVSDHMEQIIKMIEKIIENGCGYAVGGDVFFSVDKSPSYGQLSGQRLDHTQAGKRVAVDSRKRNPADFALRKAAKSGEPSWESPWGHGRPGWHIEFDIHGGGADLKFPHHENEIAQTCAACEDSGVNYWLHNGHVTNNNVKMGKSLNNFFTIRQIAANYHPLALRHFLMSAQYRSPLNYSVSQLESSSDALYSLSPYREEMSGDVGKTQQSAEAKEMIKKVKNALKFINVSISKLKKMQKKQRMSLVVSLVEVEKAVREVLDVLGLLTTLSYGELLKDMKQKALTRAGMGEEEVLQRIEERNMARKSKDFRRSDRIRELLAFKGIFLEDVPGDTVWRPSTPLTKPKSGLGLGMTAIVFAIVFTFLGFFFYSR
What are the official names of this protein?
Cysteine--tRNA ligase 1, cytoplasmic, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PROB_CHLTE
Sequence: MSHQHPVYRRIVVKVGTNVITGRNGKLDPAILDSLTSQIAALMQDGVEVILVTSGAVSAGRGIVSLSGNLTPVETRQVLAATGQIRLINAYNDRFKKHGITGAQLLVTKGDFRDRQHYLNMRTCFEALLQQKIVPIVNENDAVAITELMFTDNDELSGLIASMLQVDANIILSNVDGLFDTQSEGNPVIEEIDPGTKNFSQYIRPGKSEFGRGGMLTKCNIAHKLSRLGITVHIANGTTPGILQTIAHGGKAGTKFIAQKPKQSRKRWVALSEGLEKGAVIINQGAIDALTSGQRATSLLPVGITGVEGSFQRGDIIRICSTDGKVIGYGMASCTAEKARSAMGQKGLKPVIHYDHLYLVP
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTFC_SHIFL
Sequence: MAIKKRSATVVPGASGAAAAVKNLQASKSSFWGELPQHVMSGISRMVPTLIMGGVILAFSQLIAYSWLKIPAEIGIMDALNSGKFSGFDLSLLKFAWLSQSFGGVLFGFAIPMFAAFVANSIGGKLAFPAGFIGGLMSTQPTQLLNFDPSTMQWATSSPVPSTFIGALIISIVAGYLVKWMNQKIQLPDFLLAFKTTFLLPILSAIFVMLAMYYVITPFGGWINGGIRTVLTAAGEKGALMYAMGIAAATAIDLGGPINKAAGFVAFSFTTDHVLPVTARSIAIVIPPIGLGLATIIDRRLTGKRLFNAQLYPQGKTAMFLAFMGISEGAIPFALESPITAIPSYMVGAIVGSTAAVWLGAVQWFPESAIWAWPLVTNLGVYMAGIALGAIITALMVVFLRLMMFRKGKLLIDSL
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
What are the official names of this protein?
Fructose-like permease IIC component, PTS system fructose-like EIIC component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IDH1_SCHPO
Sequence: MFKSLVRKSSAFQPLKYGGKYTVTLIPGDGIGRETSNAVTEIFKTANVPIEFEEIDVTGMEKNNKSSGDALHEAIQSLKRNKVGLKGILFTPFEKGGHTSFNVALRKELDIYASLVLIKNIPGFKTRHDNVDFAIIRENTEGEYSGLEHQSVPGVVESLKIITEYKSKRIAQFAFDFALQNGRKSVTCIHKANIMKLADGLFRRTFYDVANGYDAITPKDLIVDNASMQAVSRPQQFDVLVMPNLYGSILSNIGSALVGGPGVIPGANFGRDYALFEPGCRHVGLSITGRGEANPTAAILSACLMLRHLGLKDYADLINAATYSVIEEGKTLTKDLGGSASTGDFTHAILERMESL
What is the function of this protein?
Performs an essential role in the oxidative function of the citric acid cycle.  Also binds RNA; specifically to the 5'-untranslated leaders of mitochondrial mRNAs.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial, Isocitric dehydrogenase, NAD(+)-specific ICDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYL_MYCSS
Sequence: MTETPTAQPDRAADADTPQHRYTAELAGQIEGAWQQTWAVEGTFNVPNPVGELAPPDGTVPADKMFVQDMFPYPSGEGLHVGHPLGYIATDVYARYYRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGLGHDTRRSFSTTDVDFYTWTQWIFLQIYNAWFDRDANRARPIAELIGEFESGVRTLDDGRPWSELSAGERADVVDSYRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSDRLLEDLEVLDWPDKVKTMQRNWIGRSTGASVQFGTDAGDIEVFTTRPDTLFGATYLVLAPEHPLVEQLAAEQWPDDVDGRWTFGATTPREAVAAYRASIAAKSDLERQENKTKTGAFLGAYATNPANGQQVPIFIADYVLIGYGTGAIMAVPGHDQRDWEFAHEFGLPVVEVISGGDISEAAYAGDGLLVNSDYLDGLDVAAAKAAITDRLVADGRGRARVEYKLRDWLFARQRYWGEPFPIVYDSDGRPHPLPESALPVELPDVPDYSPVLFDPDDADSEPNPPLNKATDWVHVELDLGDGLQTYTRDTNVMPQWAGSSWYELRYTDPLNKEALCAKENEAYWMGPQPAEHGPDDPGGVDLYVGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPAAEVVERDGKFWFEGAEVFQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRLVVDEQSGAVRVANHEALDTDTLRALHRTVAGVSEDYAALRNNTAAAKLIEYTNHLTKEGVTARAAIEPLVLMVAPLAPHLAEELWRRLGHDTSLAHGPFPVADPQYLVTDTVEYPVQVNGKVRSRITVDADAGKDTLEAAALADEKVQAFLNGATPKKVIVVPGRLVNLVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMO_PEA
Sequence: MASTTTMRLALFSVLTLLSFHAVVSVTPLHVQHPLDPLTKEEFLAVQTIVQNKYPISNNRLAFHYIGLDDPEKDHVLRYETHPTLVSIPRKIFVVAIINSQTHEILINLRIRSIVSDNIHNGYGFPILSVDEQSLAIKLPLKYPPFIDSVKKRGLNLSEIVCSSFTMGWFGEEKNVRTVRLDCFMKESTVNIYVRPITGITIVADLDLMKIVEYHDRDIEAVPTAENTEYQVSKQSPPFGPKQHSLTSHQPQGPGFQINGHSVSWANWKFHIGFDVRAGIVISLASIYDLEKHKSRRVLYKGYISELFVPYQDPTEEFYFKTFFDSGEFGFGLSTVSLIPNRDCPPHAQFIDTYVHSANGTPILLKNAICVFEQYGNIMWRHTENGIPNESIEESRTEVNLIVRTIVTVGNYDNVIDWEFKASGSIKPSIALSGILEIKGTNIKHKDEIKEDLHGKLVSANSIGIYHDHFYIYYLDFDIDGTHNSFEKTSLKTVRIKDGSSKRKSYWTTETQTAKTESDAKITIGLAPAELVVVNPNIKTAVGNEVGYRLIPAIPAHPLLTEDDYPQIRGAFTNYNVWVTAYNRTEKWAGGLYVDHSRGDDTLAVWTKQNREIVNKDIVMWHVVGIHHVPAQEDFPIMPLLSTSFELRPTNFFERNPVLKTLSPRDVAWPGCSN
What are the official names of this protein?
Primary amine oxidase, Amine oxidase [copper-containing].
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
Protein: HYP2_TAROF
Sequence: LPKPPLLPPPVPGLAPGLPPLPVPDPVPHPPKKPP
What is the function of this protein?
Antimicrobial peptide.  Inhibits elongation of hyphae in B. sorokiniana (IC(50)=3. 8 uM) but has no effect on this process or on germination of conidia in a panel of other phytopathogenic fungi.  At concentrations above 10 uM, has antibacterial activity.
What are the official names of this protein?
Peptide ToHyp2.
Protein: TGT_CLOTE
Sequence: MYTLIKKCGNAKRGRFETPHGTIETPVFMNVGTLGVIKGAVSSMDLKEIGCQVELSNTYHLHLRPGDEVIKKMGGLHKFMNWDRPILTDSGGFQVFSLAKIRKIQEEGVYFNSHIDGRRIFMGPEESMRIQSNIASTIAMAFDECIPNPSTREYVENSVARTTRWLERCKKEMDRLNSLPDTINKKQMLFGINQGGTYEDIRKAHAKTIVDMDLDGYAIGGLAVGETHEEMYRVIDEVAPIFPDNKPLYLMGVGLPSNILEAVDRGVDFFDCVLPARNGRHGHVFTKYGKINLMNAKFELDGNPIDEGCECPACKHYSRAYIRHLFKAKEMLAMRLCVLHNLYFYNKLMEDIRKAIEGDYFKEFKEEKLHNWSGKA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.