PharMolix/UniProtQA huggingface dataset:
Protein: ORC4_XENLA
Sequence: MSKRKSKDLCLPVGECISKVHGILRQRLFQHHGKPFGVDSQHKHLVELLKRTVIHGESNSALIIGPRGSGKSMLLKGALEDIFGMKQMKETALQVNLNGLLQTTDKIALKEITRQLHLENVVGDRVFGSFAENLSFLLEALKTGDRKSSCPVLFVLDEFDLFAHHKNQTLLYNLFDIAQSAQTPVAVIGLTCRLDVMELLEKRVKSRFSHRQIHLLNSFSFSQYLQIFQEKLSLPASFPDSQFAEKWNESIKSLVESKLVEDVLQKQYNASKDVRSLHMLMLLAVCRVNVSHPHITAADFLEVFRLRNQDSKANILHGVSVLELCLIIAMKHLQDIYDGEPFNFQMVHNEFQKFIQRKAHSVYNFEKAVVIKAFEHLHQLELIKPMEGLSVRTQKEYRLMKLLLDNTQIVEALQKYPNCPTDVKQWAMSSLS
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity).
What are the official names of this protein?
Origin recognition complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the ORC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF3_PSEF5
Sequence: MIIKRDMRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVPPVCRVMDYGKSIFEKKKQIAAAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGDRAKVSLRFRGREMAHQELGMELLKRVEADLQEYGSVEQHPKMEGRQLIMVIAPKKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD51_ARATH
Sequence: MGEPKDSLALFLCHESESSLNEDDDETIERSDKQEPHFTTTIDDEDYVADLVLKENLRFETLPSKTTSSSDRLIAIDWILTTRTRFGFQHQTAYIAISYFDLFLHKRFIGLQKDETWAMRLLSVACLSLAAKMEERIVPGLSQYPQDHDFVFKPDVIRKTELLILSTLDWKMNLITPFHYFNYFLAKISQDNHSVSKDLVLLRSSDSLLALTKEISFTEYRQFVVAAVTTLLASSSTSSDIRLTREEIANKFGSISWWTSNENENVYLCYQRTLEIEERKHMTPPPEIAVSREPPASGSGAKRRLSFDDSDQSSPPAKRMRRL
What are the official names of this protein?
Cyclin-D5-1, G1/S-specific cyclin-D5-1, CycD5;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
Protein: Y596_METJA
Sequence: MEDKIEFMAKHKKWFVVKKLKIDENTEDIEIARLLASIDETVLNKIPEYLPFDMNKLYEIADGIYQKKKGRITEEEIAEVLKKLKSPATTRKLNEITESKEGKEILKAILNNIILERLGIQTRVSPKVIEKYIENSQSSNR
What are the official names of this protein?
Uncharacterized protein MJ0596.
Protein: STRA6_DANRE
Sequence: MSAETVNNYDYSDWYENAAPTKAPVEVIPPCDPTADEGLFHICIAAISLVVMLVLAILARRQKLSDNQRGLTGLLSPVNFLDHTQHKGLAVAVYGVLFCKLVGMVLSHHPLPFTKEVANKEFWMILALLYYPALYYPLLACGTLHNKVGYVLGSLLSWTHFGILVWQKVDCPKTPQIYKYYALFGSLPQIACLAFLSFQYPLLLFKGLQNTETANASEDLSSSYYRDYVKKILKKKKPTKISSSTSKPKLFDRLRDAVKSYIYTPEDVFRFPLKLAISVVVAFIALYQMALLLISGVLPTLHIVRRGVDENIAFLLAGFNIILSNDRQEVVRIVVYYLWCVEICYVSAVTLSCLVNLLMLMRSMVLHRSNLKGLYRGDSLNVFNCHRSIRPSRPALVCWMGFTSYQAAFLCLGMAIQTLVFFICILFAVFLIIIPILWGTNLMLFHIIGNLWPFWLTLVLAALIQHVASRFLFIRKDGGTRDLNNRGSLFLLSYILFLVNVMIGVVLGIWRVVITALFNIVHLGRLDISLLNRNVEAFDPGYRCYSHYLKIEVSQSHPVMKAFCGLLLQSSGQDGLSAQRIRDAEEGIQLVQQEKKQNKVSNAKRARAHWQLLYTLVNNPSLVGSRKHFQCQSSESFINGALSRTSKEGSKKDGSVNEPSKEAESAAASN
What is the function of this protein?
Retinol transporter.  Accepts retinol from the extracellular retinol-binding protein rbp4, mediates retinol transport across the cell membrane, and then transmits retinol to the cytoplasmic retinol-binding protein rbp1 (PubMed:27563101).  Required for normal vitamin A homeostasis (PubMed:18316031).
What are the official names of this protein?
Receptor for retinol uptake stra6, Stimulated by retinoic acid gene 6 protein homolog.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NAT8L_MOUSE
Sequence: MHCGPPDMVCETKIVATEDHEALPGAKKDALLVAAGAMWPPLPAAPGPAAAPPPAAGPQPHGGTGGAGPPEGRGVCIREFRAAEQEAARRIFYDGILERIPNTAFRGLRQHPRTQLLYALLAALCFAVTRSLLLTCLVPAGLLALRYYYSRKVILAYLECALHTDMADIEQYYMKPPGSCFWVAVLDGNVVGIVAARAHEEDNTVELLRMSVDSRFRGKSIAKALGRRVLEFAMLHNYSAVVLGTTAVKVAAHKLYESLGFRHMGASDHYVLPGMTLSLAERLFFQVRYHRYRLQLREE
What is the function of this protein?
Catalyzes the synthesis of N-acetylaspartate acid (NAA) from L-aspartate and acetyl-CoA (PubMed:19807691, PubMed:20385109, PubMed:20643647).  Promotes dopamine uptake by regulating TNF-alpha expression (PubMed:19014384).  Attenuates methamphetamine-induced inhibition of dopamine uptake (By similarity).
What are the official names of this protein?
N-acetylaspartate synthetase, NAA synthetase, N-acetyltransferase 8-like protein, Protein Shati.
What is the protein family that this protein belongs to?
Belongs to the camello family.
What are the subcellular locations of this protein?
Cytoplasm. Microsome membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: 3S12_HEMHA
Sequence: LECHNQQSSQTPTTQTCPGETNCYKKQWSDHRGSRTERGCGCPTVKPGIKLKCCTTDRCNK
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 2, Toxin IV.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_VARPS
Sequence: MSVTTGRNVVVVGTQWGDEGKGKLVDWLTESAQGVVRFQGGHNAGHTLVINGVKTALHLIPSGIMRPGVKCYIGNGVVLSAAKLFEEIEGLEKAGVEVRSRLRISEACPLILPFHAALDIARETYREKGGVEKIGTTGRGIGPAYEDKIARRALRVQDLKHPERFATKLRVLLDLHNHVLTQVLGAPAIDFDLVFDEAMRHAALLKPMMADVSRELNDAHKAGANLLFEGAQGTLLDVDHGTYPYVTSSNCVAGNAAAGSGVGPGMLHYILGITKAYCTRVGGGPFPTELDWATPGTPGYHMSTVGAEKGVTTGRSRRCGWFDAALLKRSAQVNGLSGLCITKLDVLDGLEKLELCTGYELDGETTDILPMGADEIERCTPIYETLEGWSESTVGVTQYDKLPVNARLYLQRIEQITGVPIHMVSTSPDRDHTIMMRHPYLAD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_ACIB5
Sequence: MQVTTEAVSGVARRLNVSVPTSRINEQFEARLKRTAKTVKINGFRPGKVPANVVRREYGASIYQEVVNDIIRDSVFEAIQQEKINAVGMPNIEKVEHKEDALVFEATVEVYPEVEVKAFDGLEVERKTAEIKDADVDTMIENLQKQRQTWAVTKGMAKKDMQVTFDFEGSIDGEKFEGGSAEDFKLVLGSGRMIPGFEDGIIGMKAGEEKVIDVTFPEDYQAENLAGKAAQFKITVKQVEKPKLPEIDAEFLKIFGVSEEEGIEKLKADVRKNMEREVRNGLRNQVKQAAFDALVAANEIEVPAAMVAQEIDRQRQQMVQQFTQQFGGAGAQSFDKSMLPDELFKEQAERSVKLGVLVSKVLADAKLEVDQARVDAYIDDMASSYEDPTEVIEYFKNDAQQRAQIEAVVLEDQVVDHILASAKVTDKAVSYEDLLKEQQARRMG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: OPSV_ORYLA
Sequence: MGKYFYLYENISKVGPYDGPQYYLAPTWAFYLQAAFMGFVFFVGTPLNFVVLLATAKYKKLRVPLNYILVNITFAGFIFVTFSVSQVFLASVRGYYFFGQTLCALEAAVGAVAGLVTSWSLAVLSFERYLVICKPFGAFKFGSNHALAAVIFTWFMGVVRCPPFFGWSRYIPEGLGCSCGPDWYTNCEEFSCASYSKFLLVTCFICPITIIIFSYSQLLGALRAVAAQQAESASTQKAEKEVSRMIIVMVASFVTCYGPYALTAQYYAYSQDENKDYRLVTIPAFFSKSSCVYNPLIYAFMNKQFNGCIMEMVFGKKMEEASEVSSKTEVSTDS
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Putative violet-sensitive opsin, KFH-V, Violet cone photoreceptor pigment.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TUSB_SALAR
Sequence: MLHTLPHCASSVDFPALLRLLKEGDALLLLQDGVTVAIEGNRFLESLRDAPITVYALKEDIDARGLGGQISDSVVRVDYTEFVRLTVKYANQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDJ_ECOHS
Sequence: MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI
What are the official names of this protein?
Phosphatase NudJ.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudJ subfamily.
Protein: YFEO_SALPA
Sequence: MFHPRARTMLLLSLPALIIGVASSLVLIAAMKIASVFQQFLWQRLPASIGIAYDSPFWIVGMLTLTGIVVGLIIRYSPGHAGPDPAIEPLISMPVSPSALPGLLLALIIGLAGGVSLGPEHPIMTINIALAAAFGSRLFPRITALDWTILASAGTIGALFGTPVAAALIFSQTLSGSNDIPMWDRLFAPLMAAAAGSLTTSLFFHPHFSLPIAHYTQMRLVDIASGAIVAAIAIAAGMVAVWCLPRLHELLHRLKNPVLILGIGGFILGILGVIGGPLTLFKGLDEMQQMAFSQTLGAGDYFTLAVVKLAALVIAAASGFRGGRIFPAVFIGAALGLMLHAHVEAVPAAITVSCAILGLVLVVTRDGWLSLFMAAVVVPDTNLLPLLCIVMLPAWLLLAGKPLLAANRHEP
What are the official names of this protein?
Putative ion-transport protein YfeO.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEPA_STRP7
Sequence: MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GPI12_YEAST
Sequence: MKMLRRTKVNFSKLLYKITKLAIVLTILYIYFTPKIVSRNNASLQHIFPHKYGDYEINLVIAHPDDEVMFFSPIISQLNSYFPRTVPFNIICLSKGNAEGLGETRVRELNESAALLLHNERAVSVQVMDFQDGMDEIWDIDSITSSLSQKIDIKNHNLNQIIVTFDSYGVSNHINHKSCYAAVKKLVDDYAQPKTKRNEQPPHVTALYLRSYKNNIVLKYNSFIWEILKILYDLISPFRRIIQALPPNTAAEKDKLSLMNTHAQYVLAFATMLNAHESQVVWFRYGWWIFSRFVFVNEFDVYTY
What is the function of this protein?
Involved in the second step of GPI biosynthesis.  De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.
What are the official names of this protein?
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase.
What is the protein family that this protein belongs to?
Belongs to the PIGL family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane.
Protein: PYRF_BACC2
Sequence: MSQSLIVALDFPGKQEVEQFLHHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKSAMRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSEAMMKKEIGIEKTLEEAVAHYAKLTKDSGLDGVVCSTLEVPKLREVCGNEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQWEGVTV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: SPHS_SYNE7
Sequence: MAAWEFALGLLTASLWRWARKWRSPVKVKPMLAAVSSLEPQLEQITTDLRDRDRLLEDLPVSFLLLDADNLVLEANRSARVLLALPPEDYCRPLLEVVRSYELDRLVARCRAANAPQTDRWTLTPVNPDPLQVVPQTPRPVQGQAIPLSNGQIGVLIEDRQELVDLAQQRNRWVSDVAHELKTPLTSIRLLAEALRDRLQDEPQVWVDRLLGETQRLGQLVQDLLELSRLEQGPSGLQKLEAVDLVALLTSVRNSLEPLAEPLRLGWAYQGPEQGFVRGDRQRLFRLWLNLVDNAIRHSPSGGCLYVELRQRGDTWICDLYDDGPGFADADLPYLFERFYRGDPSRVRPAAASSSSPGSGLGLAIARQVVEAHQGRISARNHPVTGGAWLRVQLPQEPSLTPALKIGTGRRSG
What is the function of this protein?
Member of the two-component regulatory system SphR/SphS.  Sensory kinase.  Is involved in inducible production of alkaline phosphatase in response to phosphate limitation as it is directly involved in the regulation of phoA transcription in response to phosphate limitation.  SphS functions as a protein kinase that phosphorylates SphR.
What are the official names of this protein?
Sensor protein SphS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_RICFE
Sequence: MTNTKYYPEVSSNADFAAIEREILKFWQDNNIFQKSIDDRNGESEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTVKGKKVERRFGWDCHGLPAEMQSEKELGISGRLAITNFGIEKFNSHCRASVMKYASDWEEYVTRQARWVDFKNSYKTMDKNFMESVIWAFKELYNKGLLYESMRVMPYSWACETPLSNFETRLDNSYRERADKAVTVSFVLNEIPAINGMTSRESGTTSSGDYKEYRILAWTTTPWTLPSNLALAVGSDIDYASIPKEDICYIIAASSVSKYAKELGLSGEENFEIIKGSALQGLSYKPLFDYFANHPNSFKIFAGDFVVEGDGTGIVHMAPGFGEDDQILCESKGISLVCPVDNSGKFTKEIPDLEGVQVFDANDKIIIKLKEQGNWLKTEQYIHNYPHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPFHVKDNLFGKWLENARDWSISRNRFWGTPLPVWKSDDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDELARPNPNDPTGKSTMRRIEDVFDCWFESGSMPYGQAHYPFENKKWFEDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGVILDATGQKLSKRLNNYADPLELFDKYGSDALRVTMLSSNVVKGQELLIDKDGKMVFDTLRLFIKPIWNAYHFFTMYANADSLKGELNFASQNVLDIYILSKLKIAVNKIEESLDNFDTQTAYHAVSEFFEVLNNWYIRRSRARFWKSEKDADKQNAYNTLYSCLETMAIAMSALVPMISEAIYLGLCHKRPDVIARKDLSLDEAISGNSHEIATALSVPRNDGSISVHLCNYPNLSSFEINHELVATMDNVLDICSNSLFIRSTENIRVRQPLATITIISKHNDKLKSFEDLIKDEINVKSVIYRDDLENYASKKLSINFPMLGKRLPAKMKEIIAASKKGEWEAIGGGLAICDETLNSDEYKLVLEPHVHIKGAASFENNSSLLILDLELTAELIEEGYARDIVRFIQQARKDADFSITDRILIEIISEFDLSKIIDNYGDFIKEQTLGEFSKNFTPDYVSKVELENHQIQLKVKRS
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_STRPJ
Sequence: MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEEELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKWINDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANKLLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDKQYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB_ACIB4
Sequence: MENAKTGTTTVGIVTKDGVVMGTEHRASMETFIAHKTAQKLYKLDYNIGMTTAGLVGDLQVLVRYMRAEINLYRIRRKMYMPVGAAATLLSNILNERKFFPYYVGLLVGGFDSKGYHVFAIDAAGGAIEDKYASVGSGSLFVYGVLEDRWKDDLSLDEGINLVIRGINAAMRRDAASGDGISVATITKDEGFVELSQEEVEKRMKKLKLK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CE104_RAT
Sequence: MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPKFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKVEFYISESLPEYLVPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQTTNKYNVNQVALVAINIIGDPADLGDESNTTCREKLIDHYLGHSPHNPEDPALDGTFAGRSDYISPLDDLAFDMYQDPEVAQIIRRLDERKREAAKKERYDHAKKLKQAIADLQKVGERLGRYEVEKRRAVEKEDYDLAKEKKQQMARYRAQVYEQLELHGLLQGEPEMQRPFALPLQPLASPSSPQHWKAVSSLPRTEELAAEDTCAGPILQEKPLASSPRHSAVDRSPPAAGPAPRSHVEALPYDERPLPVTRKQLEEPSAEPEVREADSDVRRRGVSAEPEPLTEKALREASSAIDTLGEALVAGAYSKMWSCREDALLALYKRLMEMPVGTQKEDLKNMLRASVFLIRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLGKLDTTYCVERAIPLLLARTGDSSARLRVMALNFIQEMALFKEVRSLQLIPSYLVQPLKTNASVHLAMSQVDLLARLLRDLGTEGSGFTVDNVMKFAVSALEHRVYEVRETAVRIILDMYRQHPALTLEHLPPDDSTTRRNLLYKAIFEGFAKIDGRPTEAEGKTQKRVVTKEAEKQKKEETKALQGLSAAPRETQAGVQEKENEAVKLKNQDPQGRKAAPPDTPEIPDNHYLDNLCIFCGERNESFTEEGLDLHYWKHCLMLTRCDHCRQVVEISSLTEHLLTECDKRDGFGKCPRCSEAVPKEELPRHIKTKECNPAKSEKVANRCPLCHENFAPGEEAWKVHLMGSAGCTMNLRKTHILCKAPAPQQGKGPMASKSGTSAPKVGSKIPTPKGGLSKSSSRTHTRR
What is the function of this protein?
Required for ciliogenesis and for structural integrity at the ciliary tip.
What are the official names of this protein?
Centrosomal protein of 104 kDa, Cep104, Glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein, Gly-, L-Glu and TCP-binding protein, GlyBP.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase non-ciliated cells, localizes to the distal ends of both the mother and daughter centrioles. In ciliated cells, present at the distal end of the daughter centriole, but not on the mother centriole, and at the tip of primary cilium. Localization at the ciliary tip is also observed in motile cilia. Throughout S phase, associated with both mother and daughter centrioles in each centrosome. During metaphase and telophase, present at both spindle poles.
Protein: ISPG_XANCB
Sequence: MYDAVTRPSPPADASAWPRRITQAVKVGNVIVGGGHPVVVQSMTNTDTADIAGSVKQVAELWRAGSEMVRLTVNNAESAAAIPRIVEKLRMMGIEVPLIGDFHYNGHQLLTAEPACAEALAKYRINPGNVGFGKKKDLQFAQLIEFAIQYDKPVRIGANWGSLDQALAAQLMDENSKRETPWDAGRVLREALIRSAVDSAERAVELGLPRERIILSAKVSGVQELIAVYRDMAARCDFALHLGLTEAGIGSKGIVASAAALSVLLQEGIGDTIRISLTPEPGQSRTQEVIVAQELLQTTGQRAFTPLVTACPGCGRTTSEFFQELAGVVQNHVRAKMPEWKISNPGAENMTLAVMGCVVNGPGESRHANIGISLPGTGEAPSAPVFVDGEKTVTLRGENIAYEFIDLIDQYVERTYVRRAG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: ARDH_CANAW
Sequence: MDSAYWSYDNIVPSFRLDGKLVILTGGSGGLAAVVSRALLAKGADVALVDMNLERTQQAARDVLQWGEEQMKGKYESPIGQVSAWSCNIGDAEAVDLTFKAINEHHGKISSVLVNTAGYAENFPAEEYPAKNAENLMKVNGLGSFYVSQAFARPLIQNNMTGSIILIGSMSGTIVNDPQPQCMYNMSKAGVIHLARSLACEWAKYNIRVNTLSPGYILTPLTRNVISGHTEMKTEWESKIPMKRMAEPKEFVGSILYLASESASSYTTGHNLVVDGGYECW
What are the official names of this protein?
D-arabinitol 2-dehydrogenase [ribulose-forming], ARDH.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TBG2_ORYSJ
Sequence: MPREIITIQVGQCGNQIGMEFWKQLCLEHGIGKDGLLEDFATQGGDRKDVFFYQADDQHYIPRALLVDLEPRVINGIQNSEYRNLYNHENIFVAEHGGGAGNNWASGYHQGEQVVDDIMDMIDREADGSDSLEGFVLCHSIAGGTGSGMGSYLLETLNDRYSKKLVQTYSVFPNQMETSDVVVQPYNSLLTLKRLTLNADCVVVLDNTALNRIAVERLHLANPTFAQTNSLVSTVMSASTTTLRYPGYMNNDLVGLLASLIPTPRCHFLMTGYTPLTVERQVNMIRKTTVLDVMRRLLQTKNIMVSSYARNKEASQAKYISILNIIQGEVDPTQVHESLQRIRERKLVNFIEWGPASIQVALSRKSPYVQTTHRVSGLMLANHTSIRHLFSKCLGQYEKLRKKQAFLDNYRKFPMFEDNDLSEFDESREIIESLVDEYKACESPDYIKWGMEDAGEANVAAALDSKLVV
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
What are the official names of this protein?
Tubulin gamma-2 chain, Gamma-2-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center.
Protein: RIHB_ECOSM
Sequence: MEKRKIILDCDPGHDDAIAMMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAESTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.  Has a clear preference for cytidine over uridine.  Strictly specific for ribonucleosides.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihB, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihB subfamily.
Protein: LYZL6_MOUSE
Sequence: MLKALFICVASCLLVVNDGNIIHRCSLAKILYEEDLDGFEGYSLPDWLCLAFVESNFNISKVNENVDGSFDYGIFQINSRYWCNDYQSHSENFCHVDCQELLSPNLISTIHCAKKIVSGPGGMKNWVEWKLHCLGRPLSYWMTGCHLG
What is the function of this protein?
May be involved sperm-egg plasma membrane adhesion and fusion during fertilization.  Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus.  Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH.  Bacteriolytic activity is pH-dependent, with a maximum at around pH 5. 6 (By similarity).
What are the official names of this protein?
Lysozyme-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted. Cell surface. Cell projection, cilium, flagellum. Note=Detected in the postacrosomal area and midpiece of mature spermatozoa (PubMed:24013621).
Protein: CLPP_DICNV
Sequence: MDIMNNLPIPMVVEQTGRGERAFDIYSRLLKERVVFLVGEVNDASANLVVAQLLFLEAENPDQDIHFYINSPGGSVTAGMSIYDTMQFIKPDVSTMVLGQAASMGAVLLAAGAAGKRYALPNSRVMIHQPLGGFRGQASDIDIHAREILFIRERLNQILAKHSGQDLETISRDTERDNFMSAERAQEYGLVDAILTHRESVSA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_CLOPE
Sequence: MANIKSAKKRIKVTEKKTLRNKMIKSALKTAIKKFEVAVQANNKAEAATLYVEAARALDMSASKGVVHKNMAARKKSRLAAKLNAMA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.