PharMolix/UniProtQA huggingface dataset:
Protein: BRDT_MACFA
Sequence: MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLKLPDYYTIIKNPMDLNTIKKRLENKYYVKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFVQKLSQMPQEEQVVGGKERIKKGTQQNIAVFSAKEKSSPNATEKVFKQQAIPSVFPKTSVSPLNVAQGASVNSSSQSVAQVTKGVKRKADTTTPATSVVKASSEFSPTFTEKSVTLPPIKENMPKNVLPDSQQQYNVVKSVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDIVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPVEPVESMPLCYIKTDITETTGRENTNEASSEGNSSGDSEDERVQRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKSKRNQPKKRKQQYIGQKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTKSEKTQPSKAVGSVSRLSESSSSSSSSSESESSSSDLSSSDSSGSESEMFPKFTEVKPNDSPSKENVKKMKNECILPEGRIGITQIECSVQDKTSANTTLVHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGDNATTMLESECQAPVQKDIKIKNADSWKSLGKSVKPSGVMKSSDELFNQFRKAAIEKEVKARTQELIRKHLEQNTKEPKVSQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSLEAQDKSKLWLLKDRNLAREKEQERRRREAMAGTIDMTLQSDIMTMFENNFD
What is the function of this protein?
Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis.  Required in late pachytene spermatocytes: plays a role in meiotic and post-meiotic cells by binding to acetylated histones at the promoter of specific meiotic and post-meiotic genes, facilitating their activation at the appropriate time.  In the post-meiotic phase of spermatogenesis, binds to hyperacetylated histones and participates in their general removal from DNA.  Also recognizes and binds a subset of butyrylated histones: able to bind histone H4 butyrylated at 'Lys-8' (H4K8ac), while it is not able to bind H4 butyrylated at 'Lys-5' (H4K5ac).  Also acts as a component of the splicing machinery in pachytene spermatocytes and round spermatids and participates in 3'-UTR truncation of specific mRNAs in post-meiotic spermatids.  Required for chromocenter organization, a structure comprised of peri-centromeric heterochromatin.
What are the official names of this protein?
Bromodomain testis-specific protein.
What are the subcellular locations of this protein?
Nucleus. Note=Detected on chromatin. Excluded from the chromocenter.
Protein: RECF_LACH4
Sequence: MYLDHFVVQNFRNLKKLDIDFDPNVNIFIGKNAQGKTNLLEAIYFLALTRSHRTNSDKELIGFGGEYTNLLGHVRKSQVDLTLRVLITQKGKKVWINRVEQAKLSKYVGQLNAILFSPEDLELIKSAPALRRRFMDQEFGQINAEYLYFASKYRQVLLQKNNYLKQLAKGKTKDQVFLDVLSDQLAGIAAEVIFRRFKFLRYLSHYASDVYAHISLGGEKLAIAYHPSVSTIEADDTVEEIYQKILANFERNKAVEMRKGTTTSGPHRDDIEFKLDGKNAHLYASQGQQRSIALSVKLAEIQLVHQLTDEYPLLLLDDVMSELDHTRQSALLNYIHGKTQTFITTTDLEGISWEIIKKPRVYHMQSGKISFEKEN
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBC_LOTJA
Sequence: METLFNGTLALTGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKASYFGGIYDTWAPGGGDVRKITNLTLSPSIIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRALVWSGEAYLSYSLAALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CLN5B_DICDI
Sequence: MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK
What are the official names of this protein?
Cln5-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the CLN5 family.
Protein: IMB_XENLA
Sequence: MELVTILEKTVSPDRNELEAAQKFLEQAAVENLPTFVVELSKVLANPANSQVARVAAGLQIKNPLTSRDPDVKAQYQQRWLAIDASARGEIKTYVLRTLGTESYRPSSASQCVAGIACAEITVNQWPQLIPQLVANVTDPNSTERMKESTLEAIGYICQDIDPEQLQHKSNEILTAIIQGMRKEEPSNNVRLAATNALLNSLEFTKANFDKESERHYIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITVEAMKNEIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPESCQLKPLVIQAMPTLIELMKDPSVVVRDTTAWTVGRICELLPEAAINDVYLAPLLQCLIEGLGAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPSSYCLSSSFEVIVQKLLETTDRPDGHQNNLRSAAYEALMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQVESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGAEFLKYMEAFKPFLTIGLKNYAEYQVCLAAVGLVGDLCRALQSNILPFCDEMMQFLLENLGNENVHRSVKPQILSVFGDVALAIGGEFKKYLDVVLNTLQQASQAQVDKSDYDMVDYLNELREGCIEAYTGIIQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDSVVACGAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKTKTLATWATKELRKLKNQA
What is the function of this protein?
Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.
What are the official names of this protein?
Importin subunit beta, Importin-90, Karyopherin subunit beta, p97.
What is the protein family that this protein belongs to?
Belongs to the importin beta family. Importin beta-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus envelope.
Protein: RS15_KORVE
Sequence: MLAREHKTNIIEQYKTHANDTGSPEVQIAILSTRITELTDHFKAHKKDHASRRGLLMMVSKRRSLLDYLKKYDTERYKSVIQKLGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GPDA_BIFLD
Sequence: MGKNITVLGAGAWGTAFGQVLADAGNTVTMWAKEQQIVEGIRDHHHNAVRLPSVEKLPDNMTATGDRAEAVKNADIVVVAIAAQFARVALVEFKGLIPDHAIVVSLMKGIERGTNKRMDEVVRESLDLPADRFAAISGPNLSKEIADRHPAATVVACTNLDNATKVAEACTTSYFKPFVTTDVIGLEMCGSLKNVTALAVGMARGAGYGENTAAMIETRGLAELTALGVAAGADPKTFFGLAGVGDLIATCGSSLSRNYTFGANLGKGLTVEEATKVSNGVAEGVPTTDAVVALGNQLDVPTPLAYQMSRVLNEGISCSEMLAGLFGHEVTGE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_RHOPS
Sequence: MRHGKVHRKLNRTAEHRKAMFANMCAALIKHEQIVTTLPKAKELRPIVEKLVTLGKKGGLDKRRQAISEMRDLDQVRKLFGVLAPRYKDRNGGYTRIIKAGFRYGDNAPMAVIEFVDRDEDAKGKDSGPTQESEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: INVS_MOUSE
Sequence: MNISEDVLSTGSSLASQVHAAAVNGDKGALQRLIVGNSALRDKEDRFGRTPLMYCVLADRVDCADALLKAGADVNKTDHSRRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLSTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHAKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNLTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLQHPSVKDDSDLEGRTSFMWAAGKGNDDVLRTMLSLKSDIDINMSDKYGGTALHAAALSGHVSTVKLLLDNDAQVDATDVMKHTPLFRACEMGHRDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGQLDTDPPRSHCSSSAPVLPCPPSPQNEGSKQDATPSKQPPASHTVQSPDPEHSRLPGRCPGRASQGDSSIDLQGTASRKPSETPIEHCRGPSACVHPRSWEGGNSSKNQGTSSVEKRRGETNGKHRRCEEGPSSARQPLCTGSGRPAEKGEDSSPAVASASQQDHPRKPNKRQDRAARPRGASQKRRTHQLRDRCSPAGSSRPGSAKGEVACADQSSLHRHTPRSKVTQDKLIGGVSSGLPLSTEASRSGCKQLYEDICASPETGVAHGPPPGQCMNIHLLPVEQRLLIIQRERSRKELFRRKNKAAAVIQRAWRSYQLRKHLSRLLHLKQLGAREVLRCTQVCTALLLQVWRKELELKFPKSISVSRTSKSPSKGSSATKYARHSVLRQIYGCSQEGKGHHPIKSSKAPAVLHLSSVNSLQSIHLDNSGRSKKFSYNLQPSSQSKNKPKL
What is the function of this protein?
Required for normal renal development and establishment of left-right axis.  Probably acts as a molecular switch between different Wnt signaling pathways.  Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome.  This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling (By similarity).  Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8.  Does not seem to be strictly required for ciliogenesis.
What are the official names of this protein?
Inversin, Inversion of embryo turning protein, Nephrocystin-2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Nucleus. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, spindle. Note=Associates with several components of the cytoskeleton including ciliary, random and polarized microtubules. During mitosis, it is recruited to mitotic spindle (By similarity). Membrane localization is dependent upon cell-cell contacts and is redistributed when cell adhesion is disrupted after incubation of the cell monolayer with low-calcium/EGTA medium. Also nuclear and perinuclear.
Protein: ISPH_NEIMF
Sequence: MNEKTIILANPRGFCAGVDRAISIVERALEEFGAPIYVRHEVVHNKFVVDNLREKGAVFIEDLAEVPPGATLVYSAHGVSKAVRQEAAERGFRVFDATCPLVTKVHKEVARLDAQDCEIIMIGHKGHVEVEGTMGQLAPGKMLLVETVGDVAKLEVRNPDKLAYVSQTTLSVDETKDIIAALNARFPNIRNPHKEDICYATTNRQTAVKELAEQCDIVIVVGSPNSSNSNRLREVAASRGIDAYMVDNAGYLQRAWFEGKNKVGVTAGASAPEVLVREVLATIRGWGHETVREGEGAEESIVFVLPKELRREGETKPDLCKR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: NEMS_LOBRE
Sequence: QDVDHVFLRF
What is the function of this protein?
Myoinhibiting neuropeptide.
What are the official names of this protein?
Myosuppressin, MS.
What is the protein family that this protein belongs to?
Belongs to the myosuppressin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPR_SYNE7
Sequence: MLESIQAVQAPYYGDVSYRTPPPDLPSLLLKERIIYLGMPLFSSDDVKRQVGFDVTELIIAQLLYLEFDNPEKPIYFYINSTGTSWYTGDAIGYETEAFAICDTMRYIKPPVHTICIGQAMGTAAMILSGGTPGNRASLPHATIVLNQPRTGAQGQASDIQIRAKEVLANKRTMLEIFARNTGQDPDRLARDTDRMLYMTPAQAVEYGLIDRVLDSRKDLPAPLPSFS
What is the function of this protein?
Has lost the two conserved residues (Ser and His) proposed to be part of the active site.  Therefore it could be inactive.
What are the official names of this protein?
Putative ATP-dependent Clp protease proteolytic subunit-like, Endopeptidase Clp-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
Protein: FIS_ECOLI
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription, as well other genes.  Plays a direct role in upstream activation of rRNA promoters.  Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion.  Prevents initiation of DNA replication from oriC.  Binds to hundreds of transcriptionally active and inactive AT-rich sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome (PubMed:16963779).
What are the official names of this protein?
DNA-binding protein Fis, Factor-for-inversion stimulation protein, Hin recombinational enhancer-binding protein.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Scattered throughout the nucleoid (PubMed:21903814).
Protein: RBS5_SOLTU
Sequence: MASSVMSSAAVATRGNGAQASMVAPFTGLKSTASFPVSRKQNLDITSIASNGGRVRCMQVWPPINMKKYETLSYLPDLSDEQLLKEVEYLLKNGWVPCLEFETEHGFVYRENNKSPGYYDGRYWTMWKLPMFGCTDATQVLAEVEEAKKAYPQAWIRIIGFDNVRQVQCISFIAYKPEGY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 5, RuBisCO small subunit 5, Ribulose bisphosphate carboxylase small chain 2C, chloroplastic, RuBisCO small subunit 2C.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPN1_PONAB
Sequence: MEAPAARLFLLLLLGTWAPAPGSASSEAPPLINEDVKRTVDLSSHLAKVTAEVVLAHLGGGSTSRATSFLLALEPELEARLAHLGVQVKGEDEEENNLEVRETKIKGKSGRFFTVRLPVALDPGAKISVIVETVYTHVLQPYPTQITQSEKQFVVFEGNHYFYSPYPTKTQTMRVKLASRNVESYTKLGNPTRSEDLLDYGPFRDVPAYSQDTFKVHYENNSPFLTITSMTRVIEVSHWGNIAVEENVDLKHTGAVLKGPFSRYDYQRQPDSGISSIRSFKTILPAAAQDVYYRDEIGNVSTSHLLILDDSVEMEIRPRFPLFGGWKTHYIVGYNLPSYEYLYNLGDQYALKMRFVDHVFDEQVIDSLTVKIILPEGAKNIEIDSPYEISRAPDELHYTYLDTFGRPVIVAYKKNLVEQHIQDIVVHYTFNKVLMLQEPLLVVAAFYILFFTVIIYVRLDFSITKDPAAEARMKVACITEQVLTLVNKRIGLYRHFDETVNRYKQSRDISTLNSGKKSLETEHKALTSEIALLQSRLKTEGSDLCDRVSEMQKLDAQVKELVLKSAVEAERLVAGKLKKDTYIENEKLISGKRQELVTKIDHILDAL
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit, Ribophorin I, RPN-I, Ribophorin-1.
What is the protein family that this protein belongs to?
Belongs to the OST1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome.
Protein: PYRD_BORPD
Sequence: MSILFQAYPLARPALFAMDAETAHEVTLAGLQRAYDCGATRRLLRTRPQAPATLMGLALDNPVGLAAGLDKNGAYIDALGNLGFGFVEVGTVTPRAQPGNPKPRMFRLPRAQALINRLGFNNQGLDAFIANVQRSQWRAQGGVLGLNIGKNADTPIERAADDYLLGLEGVYPHADYVTVNISSPNTQNLRALQGGDELSALLAQLRDKRAELADRHQRHVPLAVKIAPDLSEAQIDAIADILPRYGVDGVIATNTTLSRDAVAGQPHANEAGGLSGAPVHALSLAVIARLRQRMGPGAAIIGVGGILSGRQAREKIDAGANAVQLYTGLIYRGPALVGECASAIKAAGK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DNAJ_PROMP
Sequence: MADFYQILGVSRDADANTLKSAYRKLARQYHPDVNKDPGAEDKFKEIGKAYEALADPETRARYDQFGEAGIGGAAGMPDMGDMGGFGDLFETFFNGFGGQSSQGGRSQRRGPQQGDDLRYDLNIDFKDAIFGQQREINIPHLETCEVCRGTGAKKGTGPTTCTTCGGSGQVRRATRTPFGNFTQVAECPTCNGVGQIISDPCTSCGGNGVKQVRKKLRINIPAGVDSGTKLRVSGEGNVGLKGGPPGDLYVFIKVKNDSNLKREGINIYSEISVSYLQAILGDTVDIITVDGKVNLKIPSGTQPNSTLSLENKGVPRLGNPVARGNHQVLVKVKLPTRITEDERNLLEDLASKYTEQNSSSNSGLFSRLFGKDS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECCE3_MYCTU
Sequence: MNPIPSWPGRGRVTLVLLAVVPVALAYPWQSTRDYVLLGVAAAVVIGLFGFWRGLYFTTIARRGLAILRRRRRIAEPATCTRTTVLVWVGPPASDTNVLPLTLIARYLDRYGIRADTIRITSRVTASGDCRTWVGLTVVADDNLAALQARSARIPLQETAQVAARRLADHLREIGWEAGTAAPDEIPALVAADSRETWRGMRHTDSDYVAAYRVSANAELPDTLPAIRSRPAQETWIALEIAYAAGSSTRYTVAAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHTDAPADLLTRLHWPTPTAGAHRAPLTNAVSRT
What is the function of this protein?
Part of the ESX-3 specialized secretion system, which is important for iron and zinc uptake or homeostasis.
What are the official names of this protein?
ESX-3 secretion system protein EccE3, ESX conserved component E3, Type VII secretion system protein EccE3, T7SS protein EccE3.
What is the protein family that this protein belongs to?
Belongs to the EccE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL23_CLOBJ
Sequence: MKLTNYDIIRRPLITEKTMASMADKKYTFVVDIHANKSQIKNAIETIFDVKVEDVKTARIMGKTKRVGVHIGKRPDYKKAIVKLTEDSKTIEFFEGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: G6PI_PYRAB
Sequence: MYKEPLGVKVDFNTGVIPGAKKIVRRLSDMKGYFLDEKSWEELVKKEDPIVYEVYAIEQEEKEGDLNFATTILYPGKVGKEFFFTKGHYHSKKDRAEVYVALKGKGGMLLQTPEGEARWIPMEPGTVVYVPPYWAHRTVNTGDEPFIFLAIYPADAGHDYGTIAERGFSKIVIEENGEVKVVDNPRWKS
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSP_PLACB
Sequence: MKNFNLLVVSSILLVDLFPTNCGHNVHFSRAINLNGVSFNNVDASSLGAAQVRQSASRGRGLGENPKDEEGADKPKKKEEKKVEPKKPRENKLKQPPAGDGAPEGDGAPAAPAGDGAPAAPAGDGAPAAPAGDGAPAAPAGDGAPAAPAGDGAPAAPAGDGAPAAPAGDGAPAAPAGDGAPAAPAGDGAPAGNRAGGQPAAGGNQAGGNRAGGQPAAGGNQAGGNRAGGQPAAGGNQAGGQPAAGGNQAGAQAGGNQAGAQAGGANAGNKKAGEAGGNAGAGQGQNNEAANVPNAKLVKEYLDKIRSTLGVEWSPCSVTCGKGVRMRRKVSAANKKPEELDVNDLETEVCTMDKCAGIFNVVSNSLRLVILLVLALFN
What is the function of this protein?
In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.
What are the official names of this protein?
Circumsporozoite protein, CS.
What is the protein family that this protein belongs to?
Belongs to the plasmodium circumsporozoite protein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasm. Note=Localizes to the cytoplasm and the cell membrane in oocysts at day 6 post infection and then gradually distributes over the entire cell surface of the sporoblast and the budding sporozoites.
Protein: ZIPA_ECO57
Sequence: MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPRQPVQQPPEAQVPPQHVPRPAQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSAPQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: MSHR_MIOTA
Sequence: MPVQGSQRRLLGSLNSTPTATPHLGLAANQTGARCLEVSIPDGLFLSLGLVSLVENVLVVTAIAKNRNLHSPMYCFICCLALSDLLVSGSNMLETAVTLLLEAGALAARAAVVQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVLFSMLFIAYYDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPAHQGFGLKGAATLTILLGIFFLCWGPFFLHLTLIVLCPQHPTCSCIFKNFNLFLALIICNAIIDPLIYAFRSQELRRTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL13_KAZEX
Sequence: MAISKNLPLLKNHFRKHWQERVKVHFNQAGKKASRRDARVAKAAKIAPRPLDLLRPVVRAPTVKYNRKVRAGRGFTFGEVKAAGLTPAYARTIGIAVDHRRQNKNQEMFELNVQRLKEYQSKIIVFPRNGKVPETEQVLSTAAAFPIAQPAVETETRAVQDNGESAYRTLRMARSEKRYKGIREKRAREKAEAEAEKKK
What are the official names of this protein?
60S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.