PharMolix/UniProtQA huggingface dataset:
Protein: LONP2_MOUSE
Sequence: MSSVSPIQIPSRLPLLLTHESVLLPGSTMRTSVDTARNLQLVRSRLLKGTSLQSTILGVIPNTPDPASDTQDLPPLHRIGTAALAVQVVGSNWPKPHYTLLITGLCRFQIVQVLKEKPYPVAEVEQLDRLEEFPNICKSREELGELSEQFYRYAVQLVEMLDMSVPAVAKLRRLLDNLPREALPDILTSIIRTSNKEKLQILDAVSLEDRFKMTIPLLVRQIEGLKLLQKTRKPKQDDDKRVIAIRPIRRIPHIPGTLEDEEEEEDNDDIVMLEKKIRTSSMPEQAHKVCVKEIKRLKKMPQSMPEYALTRNYLELMVELPWNKSTTDRLDIRAARILLDNDHYAMEKLKRRVLEYLAVRQLKNNLKGPILCFVGPPGVGKTSVGRSVAKTLGREFHRIALGGVCDQSDIRGHRRTYVGSMPGRIINGLKTVGVNNPVFLLDEVDKLGKSLQGDPAAALLEVLDPEQNHNFTDHYLNVAFDLSQVLFIATANTTATIPPALLDRMEIIQVPGYTQEEKIEIAHRHLIPKQLEQHGLTPQQIQIPQHTTLAIITRYTREAGVRSLDRKFGAICRAVAVKVAEGQHKEAKLDRSDVADGEGCKEHVLEDAKPESISDTADLALPPEMPILIDSHALKDILGPPLYELEVSERLSQPGVAIGLAWTPLGGKIMFVEASRMDGEGQLTLTGQLGDVMKESAHLAISWLRSNAKKYHLTNAFGSFDLLDNTDIHLHFPAGAVTKDGPSAGVTIVTCLASLFSGRLVRSDVAMTGEITLRGLVLPVGGIKDKVLAAHRAGLKQIIIPQRNEKDLEEIPSNVRQDLSFVTASCLDEVLNAAFDGGFPVKTRPGLIDSKL
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix.  Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.  May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
What are the official names of this protein?
Lon protease homolog 2, peroxisomal, Lon protease-like protein 2, Lon protease 2, Peroxisomal Lon protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: NEC2_PSHV1
Sequence: MRSDKYSQLVSVVNAGLGACGTSATLVYIRNNARVAPTGDIITLPARLDGPPIPAEYILEAMTSLLSIRTAWLRIQNTGQAVIVAGCSTQNFHHGDVTWEPPASTVTLTTAKSLWVSASAVREMKVIQRIRTAPLAAMMFMCFYRGGKNEVTVRFAFYKSDSEPNLLKISKCVYEAIDAEATRNLPKPRGFDTPPCAVLAQRMRPLGAAEGGDRETSAQTHSPAAQAQHVMQHATATKSWGALGRTLKHKKNLGWILFTCALSLAAAFVTAYIK
What is the function of this protein?
Plays an essential role in virion nuclear egress, the first step of virion release from infected cell.  Within the host nucleus, NEC1 interacts with the newly formed capsid through the vertexes and directs it to the inner nuclear membrane by associating with NEC2.  Induces the budding of the capsid at the inner nuclear membrane as well as its envelopment into the perinuclear space.  There, the NEC1/NEC2 complex promotes the fusion of the enveloped capsid with the outer nuclear membrane and the subsequent release of the viral capsid into the cytoplasm where it will reach the secondary budding sites in the host Golgi or trans-Golgi network.
What are the official names of this protein?
Nuclear egress protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae NEC2 protein family.
What are the subcellular locations of this protein?
Host nucleus inner membrane; Single-pass membrane protein. Note=Localizes also at the transient membrane of perinuclear virions.
Protein: RL16_BORAP
Sequence: MLSPKKVKYRKKQRGRLSGEAQKGNKISFGEYGLVSLETNFITARQIEAARIAMTRKIKRGGRVWIRIFPDIPYTKKPAETRMGKGKGGVDHWNAPVKLGTVMFEMAGVVEELAQEAMSLASSKLPVKTMFVVRRDLR
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: Y368_TREPA
Sequence: MRLRGVAGALLGAVVLVALGLMGVWWVFYPKKGDRGAAVAREPVLLHIDPAQMEAADEPLTLPPIERSRERMSAWSEQECLRQLEYPTEKAVQALEHANEKRIQQMLEAVP
What are the official names of this protein?
Uncharacterized protein TP_0368.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RSMH_LEGPH
Sequence: MAKHQSVLLHESIKGLAIKADGIYFDGTFGRGGHSREILNHLSDKGRLFAIDKDLDAVQYAKDYFGLDKRFQIFHGSFAQIKEFASQAGVIGAVDGILLDLGVSSPQLDNPERGFSFMLQGPLDMRMDLTQSINAANFVNEAEVNELAHVFRAYGEERFAGRIAKAIVDARKLKPITTTLELAEIVKEANPKWEKHKHPATRVFQAIRIHVNQELTDLSNCLEQCLDVLGPGGRLAVISFHSLEDRIVKQFMRDKEQGNRPPVEVPIKYEELKTNFKKVGKAVKPQSSEIKENVRSRSAVLRIGEKLA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCOA3_MOUSE
Sequence: MSGLGESSLDPLAAESRKRKLPCDAPGQGLVYSGEKWRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISSDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYSILHEPRRKDFLNTYQNPQLMEFLGLMRTRDKKAPYILIVRMLMKTHDILEDVNASPETRQRYETMQCFALSQPRAMLEEGEDLQCCMICVARRVTAPFPSSPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYVHGHAETPVYRFSLADGTIVSAQTKSKLFRNPVTNDRHGFISTHFLQREQNGYRPNPIPQDKGIRPPAAGCGVSMSPNQNVQMMGSRTYGVPDPSNTGQMGGARYGASSSVASLTPGQSLQSPSSYQNSSYGLSMSSPPHGSPGLGPNQQNIMISPRNRGSPKMASHQFSPAAGAHSPMGPSGNTGSHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMNISQPSKVSGQDSKSPLGLYCEQNPVESSVCQSNSRDPQVKKESKESSGEVSETPRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDPNCKDSSVSVTSPSGVSSSTSGTVSSTSNVHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSTASCGEGTTRQEQLSPKKKENNALLRYLLDRDDPSDVLAKELQPQADSGDSKLSQCSCSTNPSSGQEKDPKIKTETNDEVSGDLDNLDAILGDLTSSDFYNNPTNGGHPGAKQQMFAGPSSLGLRSPQPVQSVRPPYNRAVSLDSPVSVGSGPPVKNVSAFPGLPKQPILAGNPRMMDSQENYGANMGPNRNVPVNPTSSPGDWGLANSRASRMEPLASSPLGRTGADYSATLPRPAMGGSVPTLPLRSNRLPGARPSLQQQQQQQQQQQQQQQQQQQQQQQMLQMRTGEIPMGMGVNPYSPAVQSNQPGSWPEGMLSMEQGPHGSQNRPLLRNSLDDLLGPPSNAEGQSDERALLDQLHTFLSNTDATGLEEIDRALGIPELVNQGQALESKQDVFQGQEAAVMMDQKAALYGQTYPAQGPPLQGGFNLQGQSPSFNSMMGQISQQGSFPLQGMHPRAGLVRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALEMKMENPAGTAVMRPMMPQAFFNAQMAAQQKRELMSHHLQQQRMAMMMSQPQPQAFSPPPNVTASPSMDGVLAGSAMPQAPPQQFPYPANYGMGQPPEPAFGRGSSPPSAMMSSRMGPSQNAMVQHPQPTPMYQPSDMKGWPSGNLARNGSFPQQQFAPQGNPAAYNMVHMNSSGGHLGQMAMTPMPMSGMPMGPDQKYC
What is the function of this protein?
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion.  Plays a central role in creating a multisubunit coactivator complex, probably via remodeling of chromatin.  Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs).  Displays histone acetyltransferase activity.  Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit (By similarity).
What are the official names of this protein?
Nuclear receptor coactivator 3, NCoA-3, Amplified in breast cancer-1 protein homolog, AIB-1, CBP-interacting protein, p/CIP, pCIP, Receptor-associated coactivator 3, RAC-3, Steroid receptor coactivator protein 3, SRC-3, Thyroid hormone receptor activator molecule 1, ACTR, TRAM-1.
What is the protein family that this protein belongs to?
Belongs to the SRC/p160 nuclear receptor coactivator family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly cytoplasmic and weakly nuclear. Upon TNF activation and subsequent phosphorylation, it translocates from the cytoplasm to the nucleus (By similarity).
Protein: NAHC_PSEAI
Sequence: MSKQAAVIELGYMGISVKDPDAWKSFATDMLGLQVLDEGEKDRFYLRMDYWHHRIVVHHNGQDDLEYLGWRVAGKPEFEALGQKLIDAGYKIRICDKVEAQERMVLGLMKTEDPGGNPTEIFWGPRIDMSNPFHPGRPLHGKFVTGDQGLGHCIVRQTDVAEAHKFYSLLGFRGDVEYRIPLPNGMTAELSFMHCNARDHSIAFGAMPAAKRLNHLMLEYTHMEDLGYTHQQFVKNEIDIALQLGIHANDKALTFYGATPSGWLIEPGWRGATAIDEAEYYVGDIFGHGVEATGYGLDVKLS
What is the function of this protein?
Involved in the naphthalene catabolic pathway.  Catalyzes the meta-cleavage of 1,2-dihydroxynaphthalene (1,2-DHN) to yield 2-hydroxychromene-2-carboxylic acid (By similarity).
What are the official names of this protein?
1,2-dihydroxynaphthalene dioxygenase, 1,2-DHN dioxygenase, DHNDO, 1,2-dihydroxynaphthalene oxygenase.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
Protein: NUOK_XANAC
Sequence: MITLGHLLGLGAVLFCISLAGIFLNRKNVIVLLMSIELMLLSVNVNFIAFSRELGDTAGQLFVFFILTVAAAEAAIGLAILVTLFRTRRTINVAEVDTLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSP2_GLORO
Sequence: MAQLPPGDIATMPNQKVVFNAPFDNKATYYVRVINPGTNRIGFAFKTTKPKRINMNPPNGVLGPKESVNVAISCDAFDPSSEDTKGDRVTVEWCNTPDPAAAAFKLEWFQGDGMVRRKNLPIEYNV
What is the function of this protein?
Central component in molecular interactions underlying sperm crawling.  Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod (By similarity).
What are the official names of this protein?
Major sperm protein 2.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasm, cytoskeleton.
Protein: ARNF_SALSV
Sequence: MGVMWGLISVAIASLAQLSLGFAMMRLPSIAHPLAFISGLGAFNAATLALFAGLAGYLVSVFCWQKTLHTLALSKAYALLSLSYVLVWVASMLLPGLQGAFSLKAMLGVLCIMAGVMLIFLPARS
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURL_RHOPT
Sequence: MSAPEPKITPELIASHGLKPDEYQRILDLIGREPTFTELGIFSAMWNEHCSYKSSRIHLKGLPTKAPWVLQGPGENAGVIDIGDNQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTMGARPIACLNALSFGDPSHPKTRHLVSGVVAGVGGYGNSFGVPTVGGQTRFHTRYDGNILVNAMAVGLADADKIFLAAASGVGMPIVYLGSKTGRDGMGGATMASAEFDEGSDEKRPTVQVGDPFAEKLLLEACLEIMAKDCVIAIQDMGAAGLTCSAVEMGAKGDLGVELDLDAVPTRETGMTAYEMMLSESQERMLMVLKPEKEKEAEEIFKKWGLDFAIVGYTTPTKRFVVKHGGQVKADLPIKELGDEAPLYDRPWVESPKLPVIHARDINAPMGAAEALEKLLATPDLCSKRWVWEQYDHVIGGNTVQRPGGDAAVVRIEDGPKGLALTVDVTPRYCEADPFEGGKQAVAEAYRNITAVGGKPLAITDNLNFGNPERPEIMGQLVGCLKGISEACIALDSPIVSGNVSLYNETSGRGILPTPSIGGVGVLDDFTKSATLAFKAEGEAILLIGETKGWLGQSVYLREICGREEGAPPPVDLAVEKRHGDVVRGMIHAGTATAVHDVSDGGLLVAIAEMAIAGNIGASLDAPPGETVSHAWWFGEDQARYVVTVKEADLLAVKTKLKTIGVPCTQIGVTGGHALKIEGERTVDLKALRHAHEHWLPDYMGGKN
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF_CUCME
Sequence: MSWQVYVDEHLMCEIEGNHLTSAAIIGQDGSVWAQSQNFPQLKPEEVAGIVGDFADPGTLAPTGLYIGGTKYMVIQGEPGAVIRGKKGPGGATVKKTGMALVIGIYDEPMTPGQCNMIVERLGDYLIDQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin, Pollen allergen Cuc m 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ADPRH_STAAW
Sequence: METLKSNKARLEYLINDMHRERNDNDVLVMPSSFEDLWELYRGLANVRPALPVSDEYLAVQDAMLSDLNRQHVTDLKDLKPIKGDNIFVWQGDITTLKIDAIVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEIIRQQGRNEGVGKAKITRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQHSLNHVAFCCISTGVFAFPQDEAAEIAVRTVESYLKETNSTLKVVFNVFTDKDLQLYKEAFNRDAE
What is the function of this protein?
ADP-ribose glycohydrolase that hydrolyzes ADP-ribosyl-cysteine bonds (By similarity).  Specifically reverses the SirTM-mediated mono-ADP-ribosylation of GcvH-L, by releasing ADP-ribose from the target protein.  May be involved in the modulation of the response to host-derived oxidative stress.
What are the official names of this protein?
Protein-ADP-ribose hydrolase, SpyMacroD.
Protein: VSR_PVMG
Sequence: MKDVTKVALLIARAMCTSSGTFVFELAFSIAECAGRPLGGGRSKYARRRRAISIARCHRCYRLWPPTVFTTRCDNKYCVPGISYNVRVAQFIDEGVTEVIPSVINKRE
What is the function of this protein?
Suppressor of viral-induced RNA silencing.  The potential mechanism of action is based on sequestering siRNAs.
What are the official names of this protein?
RNA silencing suppressor, 12 kDa protein, Cysteine-rich protein, CRP, Nucleic acid-binding regulatory protein, PR12.
What is the protein family that this protein belongs to?
Belongs to the carlaviruses nucleic acid-binding protein family.
Protein: TRAM1_PONAB
Sequence: MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLPATEEQATESASLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKREDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICITQAFMVWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGTENGVNGTLTSNVADSPRNKKEKSS
What is the function of this protein?
Involved in the translocation of nascent protein chains into or through the endoplasmic reticulum (ER) membrane by facilitating the proper chain positioning at the SEC61 channel.  Regulates the exposure of nascent secretory protein chain to the cytosol during translocation into the ER.  May affect the phospholipid bilayer in the vicinity of the lateral gate of the SEC61 channel, thereby facilitating ER protein transport.  Intimately associates with transmembrane (TM) domain of nascent membrane proteins during the entire integration process into the ER membrane.  Associates with the second TM domain of G-protein-coupled receptor opsin/OPSD nascent chain in the ER membrane, which may facilitate its integration into the membrane.  Under conditions of ER stress, participates in the disposal of misfolded ER membrane proteins during the unfolded protein response (UPR), an integrated stress response (ISR) pathway, by selectively retrotranslocating misfolded ER-membrane proteins from the ER into the cytosol where they are ubiquitinated and degraded by the proteasome.
What are the official names of this protein?
Translocating chain-associated membrane protein 1, Protein TRAM1.
What is the protein family that this protein belongs to?
Belongs to the TRAM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ODPB_STAAU
Sequence: MAQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGIGGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFGGGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLISSIRSNDPVVYLEHMKLYRSFREEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQPIDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAELSERAILSLEAPIGRVAAADTIYPFTQAENVWLPNKNDIIEKAKETLEF
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.
Protein: IKA1B_XENLA
Sequence: MHKSHLDSVAPQLRSDLQCIKASSSSLCDQMECMLRVLQDFKRSSPPPSPDIEKPCVVPPRRAPRRDNRISHRTSDLSEADSACCMDLPSDVSPGSCGQRGLEWDSGYSEVSGGSLRGEEDDIVEEESETSVPTVVLRRLPTPSCQRLSSGGFLNSRQGRIRPKSTSDVCLEQWRGIGLGSDSQDWTGCLLSQSRSRQPLVLGDNSFADLVKQWMDLPENVDEEGRRVRDGGRWLHKPHGFLISLSGNVKRRLGNMSRLRRSEQEAVKRMSCPQLGCRPLSLYYHQSLSDIAEASTNLLHCRSRQPIICNEGAGFL
What is the function of this protein?
Inhibitor of the serine/threonine-protein kinase pak4/pak5.  Acts by binding pak4/pak5 in a substrate-like manner, inhibiting the protein kinase activity.
What are the official names of this protein?
PAK4-inhibitor inka2, Induced in neural crest by AP2-alpha protein B, IncaB.
What is the protein family that this protein belongs to?
Belongs to the INKA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TOS8_YEAST
Sequence: MGTSIVNLNQKIELPPIQVLFESLNRENETKPHFEERRLYQPNPSFVPRTNIAVGSPVNPVPVSSPVFFIGPSPQRSIQNHNAIMTQNIRQYPVIYNNNREVISTGERNYIITVGGPPVTSSQPEYEHISTPNFYQEQRLAQPHPVNESMMIGGYTNPQPISISRGKMLSGNISTNSVRGSNNGYSAKEKKHKAHGKRSNLPKATVSILNKWLHEHVNNPYPTVQEKRELLAKTGLTKLQISNWFINARRRKIFSGQNDANNFRRKFSSSTNLAKF
What are the official names of this protein?
Homeobox protein TOS8, Target of SBF 8.
What is the protein family that this protein belongs to?
Belongs to the TALE/CUP9 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YS039_HUMAN
Sequence: MVPLFITSDSALTYSPLPEPPPTPALGGQRGPPTCQCPDFPYPVPPSEGCPSGRLLLSLHWDWGRGAGGSWSGGAWPGSPGWRLARGPAHGASAESLGPLGKALVTGWEGGWRGGQGGACSPWYFPIPAAL
What are the official names of this protein?
Putative uncharacterized protein FLJ26174.
Protein: COF1_XENTR
Sequence: MASGVMVSDDVIKVFNDMKVRHQLSPEEAKKRKKAVVFCLSEDKKMIILEPGKEILQGDVGCNVDDPYKAFVKMLPRNDCRYALYDALYETKETKKEDLVFVFWAPEEASLKSKMIYASSKDAIKKRFPGIKHEWQTNTFEDINDPCNLAEKLGGSTVISLEGKTLKS
What is the function of this protein?
May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity).  Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity.  Required for formation of the cleavage furrow during cytokinesis.
What are the official names of this protein?
Cofilin-1, ADF/cofilin.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Membrane. Note=Cellular localization varies throughout development and may be related to phosphorylation levels. Shows diffuse cortical cytoplasm localization in oocytes, with membrane-association increasing after fertilization, particularly in the vegetal hemisphere (By similarity).
Protein: CCMA_SHIDS
Sequence: MGMLEVRELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTMLLRLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDGDTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAIDVNGVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTRAV
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VSPCA_AGKPL
Sequence: MVLIRVLANLLILHLSYAQKSSELVIGGDECNINEHRFLALVYANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLNKDALRRFPKEKYFCLNIRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSVGSVCRVMGWGTITSPNATLPDVPHCANINILDYAVCQAAYRGLAATTLCSGILEGGKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGVYTKVFDYTDWIQSIISGNTDAACPP
What is the function of this protein?
Snake venom serine protease that selectively cleaves the heavy chain of protein C (PROC).  This activation is thrombomodulin-independent.
What are the official names of this protein?
Protein C activator, APL-C, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TXB3A_SCOAL
Sequence: MFQFCLLILLLAPGRFFSALGKPQETLTVENREGSDSKAIPTCREASFCAFLQINPIDSNLDVLPTCTCTGGTTCSHSWDPNDGKSITEGHRQFKFCSNVLDTIKHECSAEEKALTGIFEEDKVTKIHLAYYGFLHCICPDHSDYPENSYNETETVEGDKKIITEYYHCEQFKTCKSDDTCHALAIGETKKIYYKDCNCPEGQTCPFELNSAYKTEYKETTDKFTTYSMRCQ
What are the official names of this protein?
U-scoloptoxin(11)-Sa3a, U-SLPTX(11)-Sa3a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-11 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HMO_AMYOR
Sequence: MTYVSLADLERAARDVLPGEIFDFLAGGSGTEASLVANRTALERVFVIPRMLRDLTDVTTEIDIFGRRAALPMAVAPVAYQRLFHPEGELAVARAARDAGVPYTICTLSSVSLEEIAAVGGRPWFQLYWLRDEKRSLDLVRRAEDAGCEAIVFTVDVPWMGRRLRDMRNGFALPEWVTAANFDAGTAAHRRTQGVSAVADHTAREFAPATWESVEAVRAHTDLPVVLKGILAVEDARRAVDAGAGGIVVSNHGGRQLDGAVPGIEMLGEIVAAVSGGCEVLVDGGIRSGGDVLKATALGASAVLVGRPVMWALAAAGQDGVRQLLELLAEEVRDAMGLAGCESVGAARRLNTKLGVV
What is the function of this protein?
Catalyzes the oxidation of p-hydroxymandelate to p-hydroxybenzoylformate in the biosynthesis of L-(4-hydroxyphenyl)glycine and L-(3,5-dihydroxyphenyl)glycine, 2 non-proteinogenic amino acids occurring in the vancomycin group of antibiotics.
What are the official names of this protein?
4-hydroxymandelate oxidase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
Protein: QUEA_HYDS0
Sequence: MDISLFDYDLPEELIAKYPVNPRHSAKLMVLDRKSSNITHSTFWHIDEFLEEGDLLIFNDTKVLPARLLGKKKGIENSNVEILLLRHLENEKWEALVGGKNIKPGLVIEISYDFEAIVESQIEKSKFLVLLKAKNQNQIEAINKYGKIPIPPYLGRDEEPIDKEFYQTVFAKKEFSVAAPTASLHFSNELLEKLKKKVNIDFVTLHVSYGTFKPVTVQNIEEHKVDEEYIEVSESLIKNIKKTKKMCKRVIAVGTTVTRALETAIDKPYFGFTDLYIKPGFKFKVLDGFITNFHLPKSSLLILVSAFCNEENLDGREFILKSYKEAVKHKYRFYSYGDGMLIL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.