PharMolix/UniProtQA huggingface dataset:
Protein: SYI_HALHL
Sequence: MSEYKHTLNLPHTEFPMRARLAEREPQRLQRWEEEDLYGAIRRARAGRERFILHDGPPYANGDIHIGHAVNKILKDIIVKARTLDGYDAPYIPGWDCHGLPIEHKVEEQAGKPGAELTYAQFRERCRAFAAEQVEGQRQDFKRLGVLGDWERPYLTMDYATEAGILRALARIFEGGHVTQGFKPVHWCADCGSALAEAEVEYEERTSPAVDVRFAVVDELALQQRVLLEGEGVQAGTASVVIWTTTPWTLPANRAVAVHPELEYVVVALDHSERLVLAAELLEATLQRAGVECYEVVGRCRGADLEGLSLQHPFLDRQVPVVLGEHVTTDGGTGCVHTAPGHGQEDFEVGQCYGLEVTNPVDGAGCFFEDTEHFAGLNVFDANPRVVEVLESRGALFHHEKYRHSYPHCWRHKTPVIFRATPQWFIDLDRHGMRECALAGIEGVRWMPDWGQARIDAMVRGRPDWCISRQRHWGVPIAVFIHRRSGEPHPQTPQHMEAVAARMEHEGLEAWWDLDPAELLGDEAAEYEKVTDILDVWFDSGVTHATVLEQREGLQVPADLYLEGSDQHRGWFQSSLLSSAAIRQAAPYRGVLTHGFTVDEQGHKMSKSRGNVVAPQDVMDRLGADILRLWVASADYSGEIAVSDNILQRTADAYRRMRNTARFLLGNLHGFEPGRDALVAEQLLPLDRWAVARTRALQERIVAAYDRYELHRIYHLLHNFCVVDMGGFYLDVLKDRLYTTPADSRARRSGQTAMYHIAEALVRWLAPILSFTADEIWGHLPGERREPVFTAEWYDGLFPLDDEPAEAAFWDRVMEVRTAVSRELERLRNEKVIGANLDAEVDLYVSSALAEELAPLGDELRFVLITSAARIHAATEAPVDAASATLEDGSEVRIAVAASAHDKCPRCWHRSPDIGASDEHPELCGRCVENVAGSGEYRATA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNF_BOVIN
Sequence: MGSGGVIHCRCAKCFCYPSKRRIRRRPRNLTILNLPEDALFHILKWLSVGDILAVRAVHSHLKYLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLRASRYFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQKTHRASILHCLGRVLSLFEDEEKQKQARKLFEESANQGCLTSSYLLWESDRRMDMLDPGRCLHSFRKLRDFAAKGCWEAQLSLAKACAHGHQLGLEAKASSEIVCQLFQASHAVNKQRVFSVQKGLNDTMRYILIDWLVEVATMKDFSSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEVVSALDGKIRVPTVVDYKDVLLTLVPMAPRTQHLCSFLCELSLLHTSLAAYAPAHLAAAALLLARLTHGQTQPWTTQLWDLTGFSCEDLIPCVLSLHQKCFHDDAPKDYRQVSLTAVKQRFEDKRYEEISLEEVLSYGQLCAALGVKQESLEPAPFLSAGDIHAFLSSPSARRTKRKRENSLQEDRGSFVTTPTAELSSQEETLLGSFLDWSLDYCSGYEGDQESEGEKEGDVTAPSGVLDVTVVYLSPEEHCCQESSDEEACPEEACGAQDTQALVPGHQALRTPGPEPPLCSRWGLGKDVTTSGYSSVNSASPTDSGRTSGGPPRSTSELPTGSSLNTQPCHHHARKSCLQCRPPSPPESCAPQQQVKRKNLSAHSEEEEEDMNLGFLKL
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  The SCF(CCNF) E3 ubiquitin-protein ligase complex is an integral component of the ubiquitin proteasome system (UPS) and links proteasome degradation to the cell cycle (By similarity).  Mediates the substrate recognition and the proteasomal degradation of various target proteins involved in the regulation of cell cycle progression and in the maintenance of genome stability (By similarity).  Mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication (By similarity).  In G2, mediates the ubiquitination and proteasomal degradation of CDC6, thereby suppressing DNA re-replication and preventing genome instability (By similarity).  Involved in the ubiquitination and degradation of the substrate adapter CDH1 of the anaphase-promoting complex (APC/C), thereby acting as an antagonist of APC/C in regulating G1 progression and S phase entry (By similarity).  May play a role in the G2 cell cycle checkpoint control after DNA damage, possibly by promoting the ubiquitination of MYBL2/BMYB (By similarity).
What are the official names of this protein?
Cyclin-F.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localization in the centrosome is rare in S phase cells and increases in G2 cells, Localizes on both the mother and daughter centrioles. Localization to centrosomes is not dependent on CP110. Localizes to the nucleus in G2 phase.
Protein: SH_MUMPM
Sequence: MPAIQPPLYPTFLLLILLSLIITLYVWIISTITYKTAVRHAALHQRSFSRWSLDHSL
What is the function of this protein?
Plays a role in the inhibition of the host NF-kappa-B pathway.  This inhibition occurs at the receptor level, by preventing the signaling of TNFR1 as well as IL-1R and TLR3.
What are the official names of this protein?
Small hydrophobic protein.
What is the protein family that this protein belongs to?
Belongs to the rubulavirus small hydrophobic protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: DRNE_VIBCH
Sequence: MMIFRFVTTLAASLPLLTFAAPISFSHAKNEAVKIYRDHPVSFYCGCEIRWQGKKGIPDLESCGYQVRKNENRASRIEWEHVVPAWQFGHQLQCWQQGGRKNCTRTSPEFNQMEADLHNLTPAIGEVNGDRSNFSFSQWNGVDGVTYGQCEMQVNFKERTAMPPERARGAIARTYLYMSEQYGLRLSKAQSQLMQAWNNQYPVSEWECVRDQRIEKVQGNSNRFVREQCPN
What are the official names of this protein?
Extracellular deoxyribonuclease, DNase.
What is the protein family that this protein belongs to?
Belongs to the EndA/NucM nuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYS_HELAH
Sequence: MIDRKLLLQDFDKVAHSLKKRNSVIDDGLERLREIITHYKKQLIELESLQAFQNKVSKEFGIKMTQKVDASDLKKELENNKIKLNELSKSVSELEQKIDLKLSIIPNLVDEKTPLGTSEEDNIEIKKILTPRDFTFTPKEHFELAQKNGWIDFESGVKLAKSRFSVIRGFGAKVYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLYNDTIISVEKLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPKESDVMQEYMLESASGILKALELPHRFVQLCSGDLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLVHTLNGSSLAVGRTMVALMENHQQADGSIHIPKALEKYL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_CHLTB
Sequence: MMDFLKRFFGSSQERILKRFQKLVEEVNACDEKFSSLSDDELREKTPQLKQRYQDGESLDKLLPEAYGVVKNVCRRLAGTPVEVSGYHQQWDMVPYDVQILGAIAMHKGFITEMQTGEGKTLTAVMPLYLNALTGKPVHLVTVNDYLAQRDCEWVGSVLRWLGLTTGVLVSGSPPEKRKAIYQCDVVYGTASEFGFDYLRDNSIATRKEEQVGRGFYFAIIDEIDSVLIDEARTPLIISGPGEKHNPVYFELKDRVAELVYFQREMCNHIAIEARKVLDPFLGTDVLPKDKKVMEAISEACRALWLVSKGMPLNRVLRRVREHPDLRAMIDKWDVFYHAEQNKEECLEKLSSLYIVVDEHNNDFELTDKGMLQWIEKIGGAAEDFVMMDMGHEYALIEEDATLSPADKLNRKIAVSEKDTQRKARAHGLRQLLRAHLLMEKDIDYIVRDDQIVIIDEHTGRPQPGRRFSEGLHQAIEAKEHVTIRKESQTFATVTLQNFFRLYEKLAGMTGTAITESREFKEIYSLYVLQVPTFKPCLRIDHNDAFYMTEREKYQAIVAEIISAHRSGKPILIGTESVEVSEKLSRILRQNRINHTVLNAKNHAQEAEIIAGAGKVGAVTVATNMAGRGTDIKLDEEAVAAGGLYVIGTSRHQSRRIDRQLRGRCARLGDPGAAKFFLSFEDRLMRLFASPKLNTLIRHFRPPEGEAMSDPMFDRLIETAQKRVEGRNYTIRKHTLEYDDVMNKQRQTIYAFRNDVLHAEDLFVVAKEQIEHVALALAFLILKDAHADHCSLPKIEEWLSYSFPVKLDDQEIRRLGDVDAVADYIGDLLIEAFDVKFSAMLAEFTEIIGSAANAQGICNDILRSVIISHIDEEWKVHLVDMDLLRSEVGLRSVGQKDPLIEFKNESFLLFEGLIRDIRIAIVKHLFALELSLTRSDRPDNAIPTVATAFHNHDNFRPMELTIVGEEEES
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: COMGB_BACSU
Sequence: MTAGGYTLLDGLRLMELQMNKRQAADLTDSVTCLREGAPFYQVLKSLSFHKEAVGICYFAETHGELPASMIQSGELLERKIAQADQLKRVLRYPLFLIFTVAVMFYMLQSIIIPQFSGIYQSMNMETSRSTDMLFAFFQHIDLVIILLVLFTAGIGIYYWLVFKKKSPARQMLICIRIPLVGKLVKLFNSYFFSLQLSSLLKSGLSIYDSLNAFKHQTFLPFYRCEAEQLIERLKAGESIESAICGSLFYETDLSKVISHGQLSGRLDRELFTYSQFILQRLEHKAQKWTGILQPMIYGFVAAMILLVYLSMLVPMYQMMNQM
What is the function of this protein?
Required for transformation and DNA binding.
What are the official names of this protein?
ComG operon protein 2.
What is the protein family that this protein belongs to?
Belongs to the GSP F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: T178A_XENLA
Sequence: MESRGLVTAVSLTLSICSLLLLVTAIFTDHWYETDTRKHKEMCDSQGNSDPTEQKNRLMPLYQLPFRGDPSNTRRLGLLSPAPAGGVREPEDLLENWRSLLGLGVLESDCGRPLFSTYSGLWRKCYIMGIDKDIDSLIIKGIAQKCTAIKYHFSHPIRLRNIPFNLTRAIQQDEWHLLHLRRITAGFLGMAAAVLLCGCIVAAISFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASVAYELNRQPKFIYGLPSDVEHGYSWSLFCAWCSLGLIVAAGCLCTAYPFISRTKILHLKFARDSCV
What is the function of this protein?
May act as a negative regulator of osteoclast differentiation.
What are the official names of this protein?
Transmembrane protein 178A.
What is the protein family that this protein belongs to?
Belongs to the TMEM178 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GPDA_CHLPB
Sequence: MKITVLGAGSWGTTLAVLLAGKGASVRLWAHRPEFARELEASHENVRYLPGVTIPDSIRIEDDIVRAVQGASIIVTAVPSQALRETLALFRDVSLSDTIIVNVAKGIELDTGKRLSEVIPEVLPAVSPAQVAVLYGPSHAEEVSDKQPTTVVAASSCLETAEKVQEAFHTSMFRVYVNTDIIGVEIAGSVKNIIAIAAGISDGIGYGDNAKAAIITRGLAEMSRLAVSLGGEPMTVSGLSGIGDLVVTCLSRHSRNRYLGEQIGKGRSLEEVISHMNMVAEGVSTTKAVFSLSSRLGVDMPITSAVYEMLFENKPAEQAILDLMTREPKKELGY
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPM3_MOUSE
Sequence: MMEAIKKKMQMLKLDKENVLDRAEQAEAEQKQAEERSKQLEDELATMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISDELDHALNDMTSI
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
What are the official names of this protein?
Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
[Isoform 2]: Cytoplasm, cytoskeleton.
Protein: SYN_KLEP7
Sequence: MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGFSFLAVYDGSCFDPVQAVINNSLPNYNQEVLRLTTGCSVIVTGKVVASQGQGQSFEIQATSVEVTGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWVSTPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDVAGLAEAMLKYVFKAVLEERADDMQFFAERVDKDAIDRLQRFITADFAQVDYTDAVTILENCGKQFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_DESOH
Sequence: MFSQTLSKIINRKDLSREEMDRIFSDIFSGNLTDAQIGAFMAALATKGETFEELAGAAEAMRRKATRIQAASPVVVDTCGTGGDGAHTFNISTTSAFVVAGAGICVAKHGNRSVSSKCGSADVLEALGVKLDTQPEVAEEAVNEIGIGFLFAPLFHGAMKYAIVPRKELGVRTIFNMLGPLTNPAAANCQVLGVFAPQLTEMFADALNLLGARRAFVVHGHDGLDEISVCASTRVSELNDGRVQTYDISPEHFFEDRARPEDMAGGTPSENAQITRHILSGKEKGPRRNVVVVNAGAALVAAGKAEDLKAGVALAGQIIDSGKAHEKLEQLIEFTKSNG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: SECA_TRIL1
Sequence: MLSTLIRKVIGSKNERELKRLWPIVAKINSLEPQMQALSDEELRGKTAEFKERYSKGESLDALLPEAFAVCREGGRRELGMRHFDVQLIGGMTLHAGKIAEMKTGEGKTLVATLAAYLNAISGKGVHVVTVNDYLARRDSEWMGRLYGFLGLTTGVIVHGLDDEQRRANYAADITYGTNNEFGFDYLRDNMKFSLDDYVQRGFNFAVVDEVDSILIDEARTPLIISGPTEESTDKYYVINQIIPRLEQGEVKEVEANTLSGKKKVYTGDFTIDEKAKSATLTEQGVSKVEKLLKIENLYDPRNIETLHHVNQALRAHAMYRRDVDYVVKDGEVLIVDEFTGRLMPGRRWSDGLHQAVEAKEGVRIESENQTLATITFQNYFRMYAKLSGMTGTADTEAEEFHKIYKLDVTVIPTNRPLLRPDYPDVIYKTEQEKFAAVISDIKEHYEKGQPCLVGTISIEKSEVLSELLRKQGIPHFVLNAKQHEKEAEIVAQAGRKKAITIATNMAGRGTDIVLGGNPDSLLKQWRLANPEATAEQAAAMLEQYRQQCAAEHDEVVALGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLQDDLLRIFGSERVAKIMDFLKIEEGEAITHAMINKSIENAQKKVEAHNFEIRKHLIDYDDVMNKQREVIYTQRREILAGEDIRESFLEMLDDTISDIVKAYAFEKDAPLEWDWESLSETVFRCFSIQLELSREMIARLNADGLQKMLQEQAHESIKRRADELGDELMDHLIRVVMLQAIDVHWKDHLLNIDHLKEGIGLRSYGQKDPKQEYKKEAYQLFMEMIIRIREETVEKVFWVQIEKEEDIEELEEEQVERSRKMFKAITVNDDEHPAEPAKSQKNAGRNEPCPCGSGKKYKKCCGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: HIS7_ROSS1
Sequence: MPASTRTASIERRTGETSIELTLNIDGSGMVDSATGIGFLDHMLHLFARHGLFDLKVHASGDLHVDEHHTAEDVCICLGQAFDRALGERRGLVRTAHAYVPMDEALGFVAVDLSGRPYCVVDADFVTPRVGQLGTDLIAHLFESIAIHGRMNLHARVLYGRNDHHKVEALFKALGRALDMATRIDERLGGAIPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KYNU_BURMS
Sequence: MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGLIRSWNTAGWFALPRRLGDRLAPLIGAADDEVAITDTISINLFKLLAAMLRHQARHAPKRRVIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGYMHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVWVPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQTDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALIARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: TBB_USTMA
Sequence: MREIVHLQTGQCGNQVGTKFWEVLSDEHGIDHNGNYIGTSDDQLARINVYYNEASGNKYVPRAVLVDLEPGTMDSTRSGPLGGLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVIRKEAENCDMLQGFQITHSLGGGTGAGMGTLLISKIREEYPDRMMATFSVLPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYNICFKTLKLNAPTYGDLNHLVSLVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFSPLTARGSQSYRAVTIPEITQQAFDSKNMMTACDTRLGRYLTCAAYFRGKVSMKDVEDQMQSFQQKHSTQFVEWIPNNVQTAQCDIPPRGLKMSVTFIGNSTAIQDVFKRIAEQFSAMFKRKAFLHWYTGEGMDEMEFTEAESNLQDLIAEYQQYQDASALDEDIEGEYIEEEELVQE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FHA1_ARATH
Sequence: MATAVGSGSDVEVGFAKLQGEDFEYYMQSYSIILGRNSKKSTVDVDLSSLGGGMNISRNHARIFYDFTRRRFSLEVLGKNGCFVEGVLHLPGNPNVKLDSQDLLQIGDKEFYFLLPVWSILGGPLGPRHHVLGKATVVPYHNYHSGPGSGSGKNGVRSRELYEYDDEDDDEEEDIRGSGKKTWRDGHEGVYASGEKKREGRSKADREADDQQFLQLMHGSGWSVTDIKGVWKRMASQSSKKIPITRRLGYP
What is the function of this protein?
May play a role in the control of plant organ development (By similarity).  Does not show transactivation activity in yeast (PubMed:23192389).
What are the official names of this protein?
FHA domain-containing protein FHA1, Protein FORKHEAD-ASSOCIATED DOMAIN 1, AtFHA1.
What are the subcellular locations of this protein?
Nucleus. Note=Detected at discrete loci in the nucleus.
Protein: ATPH_PHATC
Sequence: MDPIISAASVIGAGLSIGLAAIGPGIGQGTAAGQAVEGIARQPEAENKIRGVLLLSLAFMEALTIYGLVVALALLFANPFNT
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KDSA_BORPE
Sequence: MMKACGFDIGLDHPFFLIAGPCVIESRELAFETAGRLKEITGKLGVPFIYKSSFDKANRSSGKSFRGPGMDEGLKILADVRAQLDVPVLTDVHDIDQVAPVAAVVDMLQTPAFLCRQTDFIRACAATLKPVNIKKGQFLAPHDMLQVARKARDAALEAGGDGNNILVCERGASFGYNNLVSDMRSLAIMRETDCPVVFDATHSVQLPGGQGASSGGQREFVPVLARAAVAVGVAGLFMETHPNPACAMSDGPNAVPLDRMAELLESLVALDRVTKRSGFLENQFV
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFGL_MYCTO
Sequence: MADRVNASQGAAAAPTANGPGGVRNVVLVGPSGGGKTTLIEALLVAAKVLSRPGSVTEGTTVCDFDEAEIRQQRSVGLAVASLAYDGIKVNLVDTPGYADFVGELRAGLRAADCALFVIAANEGVDEPTKSLWQECSQVGMPRAVVITKLDHARANYREALTAAQDAFGDKVLPLYLPSGDGLIGLLSQALYEYADGKRTTRTPAESDTERIEEARGALIEGIIEESEDESLMERYLGGETIDESVLIQDLEKAVARGSFFPVIPVCSSTGVGTLELLEVATRGFPSPMEHPLPEVFTPQGVPHAELACDNDAPLLAEVVKTTSDPYVGRVSLVRVFSGTIRPDTTVHVSGHFSSFFGGGTSNTHPDHDEDERIGVLSFPLGKQQRPAAAVVAGDICAIGKLSRAETGDTLSDKAEPLVLKPWTMPEPLLPIAIAAHAKTDEDKLSVGLGRLAAEDPTLRIEQNQETHQVVLWCMGEAHAGVVLDTLANRYGVSVDTIELRVPLRETFAGNAKGHGRHIKQSGGHGQYGVCDIEVEPLPEGSGFEFLDKVVGGAVPRQFIPSVEKGVRAQMDKGVHAGYPVVDIRVTLLDGKAHSVDSSDFAFQMAGALALREAAAATKVILLEPIDEISVLVPDDFVGAVLGDLSSRRGRVLGTETAGHDRTVIKAEVPQVELTRYAIDLRSLAHGAASFTRSFARYEPMPESAAARVKAGAG
What are the official names of this protein?
Elongation factor G-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Protein: MIAB_SHIFL
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRMAETPESVIARTRKENDLGVGYYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S12_NAJHA
Sequence: MICHNQQSSQPPTIKTCPGETNCYKKRWRDHRGTIIERGCGCPSVKKGVGIYCCKTNKCNR
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 2, Toxin CM-14, Toxin V-N-I2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FEOC_SERMA
Sequence: MAGLLQVRDALALRATSGAQLSQSLATPLPLVQAMLDRLTAMGKVERIEQDDGACLSGGCKSCPQPRGAARCSTG
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: COMD7_MOUSE
Sequence: MGRLHCTQDPVPEAVRGDMQQLNQLGAQQFSDLTEVLFHFLTEPKEVERFLAQLSEFATSNQISLGPLKSIMKSLLLVPNGALKKGLTAEQVRTDLQTLGLSEEKATYFSEKWKQNASTLAQWAMGQTLMVNQLIDMEWRFGVTSGSSELEKVGSIFLQLKLVVKKGKQTENLYMELTLPQFYSFLHEMERVRASMECLS
What is the function of this protein?
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes.  Associates with the NF-kappa-B complex and suppresses its transcriptional activity.
What are the official names of this protein?
COMM domain-containing protein 7.
What are the subcellular locations of this protein?
Cytoplasmic vesicle.
Protein: SPB4_CANGA
Sequence: MGKSLEWADLDYELQPWIKKAINVSGFDSMTPVQASTIPMFAKNKDVVVESVTGSGKTIAFVIPILEKIISEGINNSKFKKGHFYSLILAPTRELSMQIQNVVSSFLEHYPEDQYPIRSQLVVGTNEKSVRDDVNTLLDERPQILIGTPGRVLDFLQSPSVKTSSCGMVVLDEADRLLDVSFFKDVEKILNVLPKQRRTGLFSATISSAGTLIFKTGLRNPVKITVNSQGKNAPTTLNLFYSVMKPEEKLQNLIHIMNNIRFKKCIVYFSTCVSVTFFYQYLKYLQQTDKTLREDLQVISIHGKLTTQSRRKALSTFTESLSDCILLTTDVAARGIDIPDVDLVLQIDPPTDADIFLHRCGRTGRANKIGRAIVFLNEGREEDYIPFMEVKNVDIEETDINKNKISNDNNDEFYQRFTKWLLSDRANYDLSVKSYVAFIRYYSKHSATSIFRLQSLDYVSLGKMYGLFRLPRMPEITKYLQDKEKSGETVVGYYGEGWLMNPPPIDMDKYAYQDKKREKARIEELKNLAQINDKKKLKAELKKKNMAWSSKTMTKEERQERRKKLDLKRKAIELEIAAEAERDESDTEITQDWKDEILQKKKKKKVGSEMQGSFDDL
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase SPB4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.