PharMolix/UniProtQA huggingface dataset:
Protein: NAF1_DROME
Sequence: MESEQPAAVKASAPIEEPQSTETAVELGKHSTLKADLSIDKLETATTEATNAVVEPVEMEQQVENELVNESTQAMTSTTTQEKVVGSVNNLVEEQQCVEMEFETSSDLVVQGSPSEESKKVASDASATVTAPQVQPAPHVDSSPQASGLSLLAAYSSDDSDDEKVTPVQNGDNDVIEVPVTDPASSTTAYRPVVAVSSDDESSKSSSSSSDSDSDSEGEYLTVLRKKIDKRINTVDCDEDDEDFDEDGATGDRSRRRQPPKVRGEMLLDDLPPIHQLEITVPEDECVELGKVQSIVDQLVLVSVLPNSMLFDLDTVLFLEKGRKVLGEVFDVLGQVSDPLYCVRFNSNKQILDRGIKIGDVVYCAPKTEHTQFVILSKLMQVRGSDASWEHDVEPPARYVDHSDDEEEREARAEQRKRRQRDRTNSTDSVDTVTSVATTATKASSVAPPPRQRGRRGQRESFRQSQRPSINQHNQNQPQDEQYNFHPSYNPGSWHSNYYQNYHQAAANFNMAQQHPGMPFPVPNYGYGMPYAMPPMYPHMYPPPPPFAPPPPNNQSHQGQPPPS
What is the function of this protein?
RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis.  During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by GAR1/CG4038 to yield mature H/ACA snoRNPs complex (By similarity).
What are the official names of this protein?
H/ACA ribonucleoprotein complex non-core subunit NAF1.
What is the protein family that this protein belongs to?
Belongs to the NAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSA_YERPP
Sequence: MSKSENLYAQAQQLIPGGVNSPVRAFTGVGGIPLFIERADGAYLFDVDGKAYIDYVGSWGPMILGHNHPAIRQAVIEAVERGLSFGAPTEMEVKMAQLVTDLVPTMDMVRMVNSGTEATMSAIRLARGYTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPTDFAKHTLTCTYNDLASVRQAFEQYPQEVACIIVEPVAGNMNCIPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYHVIPDLTCLGKIIGGGMPVGAFGGRREVMNALAPTGPVYQAGTLSGNPIAMAAGFACLTEISQVGVYETLTELTDSLATGLRHAAKEENIPLVVNHVGGMFGLFFTNADTVTCYQDVMNCDVERFKRFFHLMLEEGVYLAPSAFEAGFMSLAHSNEDIQKTVNAARRCFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_BRUSI
Sequence: MVTANSTVKVGNVTFSNSAPLALIAGPCQMETRDHAFEMAGHLKEMTDKLGIGLVYKSSFDKANRTSLKAARGIGLEKALEVFSDLKKEYGFPVLTDIHTEEQCAAVAPVVDVLQIPAFLCRQTDLLIAAARTGRVVNVKKGQFLAPWDMKNVLAKITESGNPNVLATERGVSFGYNTLVSDMRALPIMAGLGAPVIFDATHSVQQPGGQGGSTGGQREFVETLARAAVAVGVAGLFIETHEDPDNAPSDGPNMVPIDKMPALLEKLMAFDRIAKAL
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BZAF_GEOSL
Sequence: MKTQIEQAREGIITPQMAAVAAEEHVSPEYVCRMVAEGKVVIPWNHVRAPKAVGIGKGLRTKVNASIGTSSDIVDYEAEVRKARAAQESGADTLMELSVGGDLDRVRREVIAAVDLPVGNVPLYQAFCEAARKYGDPNRLDPEMLFDLIERQCADGMAFMAVHCGINLYTIERLRRQGYRYGGLVSKGGVSMVGWMMANGRENPLYEQFDRVVGILKKYDTVLSLGNGLRAGAIHDSSDRAQIQELLINCELAEMGREMGCQMLVEGPGHVPLDEVEGNIQLQKRMSGGAPYYMLGPISTDVAPGFDHITAAIGAAQSSRFGADLICYITPAEHLALPNEEDVRQGVKAARVAAYIGDMNKYPEKGRERDREMSKARRDLDWQRQFELALYPEDARAIRASRTPEDEATCTMCGDFCASRGAGRLFAGDLRGDKV
What is the function of this protein?
Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.  Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by G. sulfurreducens.
What are the official names of this protein?
5-hydroxybenzimidazole synthase, 5-OHBza synthase, HBI synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily.
Protein: KT33A_PANTR
Sequence: MSYSCGLPNLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGGRLNVEVDAAPAVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQVEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCAITNACDKSTGPCISNPCGPRARCGPCNTFGY
What are the official names of this protein?
Keratin, type I cuticular Ha3-I, Hair keratin, type I Ha3-I, Keratin-33A, K33A.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: LEPA_CERS5
Sequence: MTQLDLIRNFSIVAHIDHGKSTLADRLIQLTGTVAERDMKAQILDSMEIERERGITIKANTVRIEYPAKDGKTYVLNLIDTPGHVDFAYEVSRSMRAVEGSLLVVDASQGVEAQTLANVYQALDAGHEIVPVLNKIDLPAAEPDRVRTQIEDVIGLDASDAVLISAKSGLGIPDVLEAIVTRLPPPKGNREAPLKAMLVDSWYDAYLGVVVMIRVMDGVIRKGDRVKMMQTGAVYGIDRLAVLKPQMVDIAELGPGEIGVLTASIKQVRDTRVGDTITHEKKGCEAPLPGFKPAQPVVFCGLFPVDANDFEGLREAIEKLALNDASFTYEMETSAALGFGFRCGFLGLLHLEVVRDRLEREYDLDLITTAPSVVYQIYMRDGTVQELHNPTDMPDLTLVDHIEEPRIRATIMVPDEYLGDVLKLCQDRRGIQLDLSYAGSRAMVVYDLPLNEVVFDFYDRLKSVTKGYASFDYQITGYREDFLVKMSILVNDEPVDALSMMVHRDRADLRGRAMVEKLKELIPRHMFKIPIQAAIGGRVIARETISAMRKDVTAKCYGGDATRKRKLLDKQKAGKKKMRQFGKVEIPQQAFINALKMDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TYPH_RHIME
Sequence: MAMLPQEIIRKKRDGDRLDPAEIAGFIAGVTDGSVSEGQAAAFAMAVWFSGMNRDECVALTLAMRDSGETLDWSDLARPIVDKHSTGGVGDNVSLMLAPIVAACGAAVPMISGRGLGHTGGTLDKLESIPGYDIQPSPELFRRVADEVGCAIIGQTADLAPADKRLYAIRDVTATVDSVPLITASILSKKLAAGLRSLVLDVKLGNGSFMTDPAETEVLARSLVEVANGAGVRTSALITDMNEPLADAAGNALEIENCLAYLRGEKAGTRLDQVVMALAAEMLVAAGIAAHEAEAEAMARRVLGSGEAMERFGLMVHRLGGPADFVDRPGAYLAKAPAILAVPAGRHGYLTSCKTRELGMAVIELGGGRIRPDDRIDHRVGLTGLRPLGTKVEKGEPIAFVHAADQSQAEAIAKRVVTLYAIADEEPARRPVIVSKLRAG
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: RL3_SHELP
Sequence: MAIGLIGRKVGMTRIFTEDGASIPVTVIEIAANRVAQVKTLETDGYRALQITTGTKKANRITKPEAGHFAKAGVEAGRGLWEMRLADGEGEGIEVGAELNVDIFADVAKVDVTGQSKGKGFQGGIKRWNFRTQDATHGNSLAHRANGSIGQNQTPGRVFKGKKMSGHMGAERVTTQNLDVVRVDAERNLLLVKGAVPGATNGDLIIKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DCUP_BACSU
Sequence: MSKRETFNETFLKAARGEKADHTPVWYMRQAGRSQPEYRKLKEKYGLFEITHQPELCAYVTRLPVEQYGVDAAILYKDIMTPLPSIGVDVEIKNGIGPVIDQPIRSLADIEKLGQIDPEQDVPYVLETIKLLVNEQLNVPLIGFSGAPFTLASYMIEGGPSKNYNKTKAFMYSMPDAWNLLMSKLADMIIVYVKAQIEAGAKAIQIFDSWVGALNQADYRTYIKPVMNRIFSELAKENVPLIMFGVGASHLAGDWHDLPLDVVGLDWRLGIDEARSKGITKTVQGNLDPSILLAPWEVIEQKTKEILDQGMESDGFIFNLGHGVFPDVSPEVLKKLTAFVHEYSQNKKMGQYS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F110B_DANRE
Sequence: MPTETLQADSKPVGQGGAFASAVPLRILNKGPDYFRRQTEPNPKRLSAVERLEADKAKYVKSQEVINAKQEPIKPQVLAKPPVCPVPLKRGGGVGSGLKASNNNAKSDTCATTTKRENLNLEILKNILNSSSSSEGPAKGTSHKVGARSWAPHRSSELSEPGCRSFTDSLKVPPSTQGRHSPQGGNLNLSRRLLEERSCEVDGERSPLHASHSSSDIRRMCNGKPLRAARSSSSSAPPLPPKPSAKALAACDNAPCSPERETLTSTAAELELGSSVARRPSLHRSKSDLSDRYARAGADVERFFNYCGLDPEELESVGVESFARANSDIVSLNFRSASMISSDCEQSRHSNDDLTDEEDDAGERVPYGISAVERNARIIKWLYSIKQARESQKVSHV
What are the official names of this protein?
Protein FAM110B.
What is the protein family that this protein belongs to?
Belongs to the FAM110 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: RIMP_STRPQ
Sequence: MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYELVDVEYDKMGSDYILSILVDKEDGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSSPGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHKIVNIPYQAVAKVRMAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_BACAH
Sequence: MNKGRVTQIMGPVVDVKFDGGKLPEIYNALTVKQSNENGTSINLTFEVALHLGDDTVRTVAMSSTDGLVRGTEVEDTGKAISVPVGDATLGRVFNVLGDAIDLDGEVPADVRRDPIHRQAPAFEELSTKVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYHEMSDSGVIKKTAMVFGQMNEPPGARQRVALTGLTMAEHFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNKGSITSIQAVYVPADDYTDPAPATTFAHLDATTNLERRLTQMGIYPAVDPLASTSRALSPEIVGEEHYEVARQVQQTLQRYKELQDIIAILGMDELSEEDKLVVHRARRIQFFLSQNFHVAEQFTGQKGSYVPVKETVRGFKEILEGKYDDLPEDAFRLVGGIEEVIENAKKMMA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MGDG2_ORYSJ
Sequence: MVISVATPRRSIRDAVLGGVLGAGGRQLYQPLRCAFYDGAAGGGLTAALSEDGAEGGVPLPCGRKTAAAKNVLILMSDTGGGHRASAEALRDAFRLEFGDAYQVFVRDLGKEYGGWPLNDMERSYKFMIRHVRLWKVAFHGTSPRWVHGMYLAALAYFYANEVVAGIMRYNPDIIISVHPLMQHIPLWVLKWQSLHPKVPFVTVITDLNTCHPTWFHHGVTRCYCPSAEVAKRALLRGLEPSQIRVYGLPIRPSFCRAVLDKDELRKELDMDPDLPAVLLMGGGEGMGPVEETARALSDELYDRRRRRPVGQIVVICGRNQVLRSTLQSSRWNVPVKIRGFEKQMEKWMGACDCIITKAGPGTIAEALIRGLPIILNDFIPGQEVGNVPYVVDNGAGVFSKDPREAARQVARWFTTHTNELRRYSLNALKLAQPEAVFDIVKDIHKLQQQPATVTRIPYSLTSSFSYSI
What is the function of this protein?
Involved in the synthesis of the major structural component of photosynthetic membranes.
What are the official names of this protein?
Probable monogalactosyldiacylglycerol synthase 2, chloroplastic, OsMGD2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane.
Protein: SNAK_DROME
Sequence: MIILWSLIVHLQLTCLHLILQTPNLEALDALEIINYQTTKYTIPEVWKEQPVATIGEDVDDQDTEDEESYLKFGDDAEVRTSVSEGLHEGAFCRRSFDGRSGYCILAYQCLHVIREYRVHGTRIDICTHRNNVPVICCPLADKHVLAQRISATKCQEYNAAARRLHLTDTGRTFSGKQCVPSVPLIVGGTPTRHGLFPHMAALGWTQGSGSKDQDIKWGCGGALVSELYVLTAAHCATSGSKPPDMVRLGARQLNETSATQQDIKILIIVLHPKYRSSAYYHDIALLKLTRRVKFSEQVRPACLWQLPELQIPTVVAAGWGRTEFLGAKSNALRQVDLDVVPQMTCKQIYRKERRLPRGIIEGQFCAGYLPGGRDTCQGDSGGPIHALLPEYNCVAFVVGITSFGKFCAAPNAPGVYTRLYSYLDWIEKIAFKQH
What is the function of this protein?
Component of the extracellular signaling pathway that establishes the dorsal-ventral pathway of the embryo.  Three proteases; ndl, gd and snk process easter to create active easter.  Active easter defines cell identities along the dorsal-ventral continuum by activating the spz ligand for the Tl receptor in the ventral region of the embryo.
What are the official names of this protein?
Serine protease snake.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GP14_BPMU
Sequence: MNNETKFTPLNIDNVMAEKGMLERVRAIVEYGIKHNLTAREVRDIINREMNRLETVVALQNETAREEYIRRRLGLSDQDIVTDAHVFEAFEIRQHLGLTN
What are the official names of this protein?
Uncharacterized protein gp14, E15, Gene product 14, gp14.
What is the protein family that this protein belongs to?
Belongs to the mulikevirus gp14 protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PUR5_CLOAB
Sequence: MVTYKDSGVNIEEGYKSVKLMKDYASKTFIPGVINNLGSFAGMFEIGSGYKNPVLVSGTDGVGTKLAVAFATKKYDTVGIDCTAMCVNDILCHGAKPVFFLDYIACGKLEAEVASDLVKGVSEGCSQAGCALIGGETAEMPGFYKEGEYDLAGFAVGLVDKDKIIDGSKIEDGNVLIGIASSGIHSNGYSLVRKLITDFNEEFNGKKIGEVLLTPTKIYVKPVLKVLESFDVKGMAHITGGGFYENIPRMFKGDFTAVINKESLEIPEIFKHIMSLGVDENHAFNTFNMGIGFVICAAKEDKDGIIASLKESGEKAYEIGYVKAGGSGVCIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_PSEF5
Sequence: MNLHEYQGKQLFAEYGLPVSKGYAVDTPEEAAEACDKIGGSEWVVKAQVHAGGRGKAGGVKLVRSKEDAKAFAQQWLGKRLVTYQTDANGQPVTKILVESCTDIAKELYLGAVVDRSSRRIVFMASTEGGVDIEKIAHDTPEKILKATIDPLVGAQPFQGRELAFQLGLEGKQVAQFAKIFVGLAKLFQDHDLALLEVNPLVIKADGDLHCLDAKINIDANAMYRQPKLKTFHDPSQDDPREAHAAKFELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTEAFKIILSDTNVAAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKIPVVVRLEGNNAELGAKVLAESGLNIIAATSLTDAAQQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: YBEY_STRPM
Sequence: MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVTNERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDFAADPSLAEMMAEFDAYIGELFISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAYGLTRQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_INBAD
Sequence: MSNMDIDGINTGTIDKTPEEITSGTSGATRPIIKPATLAPPSNKRTRNPSPERATTSSEAIVGRRTQKKQTPTEIKKSVYNMVVKLGEFYNQMMVKAGLNDDMERNLIQNAHAVERILLAATDDKKTEYQKKKNARDVKEGKEEIDHNKTGGTFYKMVRDDKTIYFSPIRITFLKEEVKTMYKTTMGSDGFSGLNHIMIGHSQMNDVCFQRSKALKRVGLDPSLISTFAGSTLPRRSGATGVAIKGGGTLVAEAIRFIGRAMADRGLLRDIRAKTAYEKILLNLKNKCSAPQQKALVDQVIGSRNPGIADIEDLTLLARSMVVVRPSVASKVVLPISINAKIPQLGFNVEEYSMVGYEAMALYNMATPVSILRMGDDAKDKSQLFFMSCFGAAYEDQRVLSALTGTEFKPRSALKCKGFHVPAKEQVEGMGAALMSIKLQFWAPMTRSGGNEVGGDGGSGQISCSPVFAVERPIALSKQAVRRMLSMNIEGRDADVKGNLLKMMNDSMAKKTNGNAFIGKKMFQISDKNKINPVDIPIKQTIPNFFFGRDTAEDYDDLDY
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RN167_MOUSE
Sequence: MHPAAFPLPVVVATVLWGAAPVRGLIRATSEHNASMDFADLPALFGATLSDEGLQGFLVEAHPENACGPIAPPPSAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSAEYLRALFVYEKGARVLLVPDNSFPLGYYLIPFTGIVGLLVLAMGTVLIVRCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDEYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEEQEEETQEQEEGDEGEPRDQPASEWTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPSPPSSAALA
What is the function of this protein?
E3 ubiquitin-protein ligase that acts as a regulator of the TORC1 signaling pathway.  Positively regulates the TORC1 signaling pathway independently of arginine levels: acts by catalyzing 'Lys-29'-polyubiquitination and degradation of CASTOR1, releasing the GATOR2 complex from CASTOR1.  Also negatively regulates the TORC1 signaling pathway in response to leucine deprivation: acts by mediating 'Lys-63'-linked polyubiquitination of SESN2, promoting SESN2-interaction with the GATOR2 complex.  Also involved in protein trafficking and localization.  Acts as a regulator of synaptic transmission by mediating ubiquitination and degradation of AMPAR receptor GluA2/GRIA2.  Does not catalyze ubiquitination of GluA1/GRIA1.  Also acts as a regulator of the recycling endosome pathway by mediating ubiquitination of VAMP3.  Regulates lysosome positioning by catalyzing ubiquitination and degradation of ARL8B.  Plays a role in growth regulation involved in G1/S transition by mediating, possibly by mediating ubiquitination of SLC22A18.  Acts with a limited set of E2 enzymes, such as UBE2D1 and UBE2N.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF167, RING finger protein 167.
What is the protein family that this protein belongs to?
Belongs to the Godzilla family.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Endomembrane system; Single-pass membrane protein. Cell membrane; Single-pass type I membrane protein. Note=Targeted to cytoplasmic membranes; mainly localizes to lysosomal membrane. A subpopulation localizes to the cell membrane of neurons.
Protein: TRUA_SINFN
Sequence: MPRYRLTVEYDGSDYVGWQRQENGPSVQGAIEKAVLSLTGETVSIRGAGRTDSGVHAMGQVAHLDLTREWKTHTLRNALNAHLALAAERVSILDAAEVPPEFDARFSAIRRHYLYRIISRRSPLALEARRAWWVPKTLDHEAMHEAAQHLVGHHDFTTFRSAHCQANSPLRTIDRLDVTRSGELIEIRATAQSFLHNQIRSFAGSLKLVGEGKWTPDDLKTALEARDRKACGPVAPPEGLFFMQVDY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LPXC_NEIMB
Sequence: MLQRTLAKSISVTGVGLHSGERVALTLHPAPENSGISFRRTDLDGEMGEQIKLTPYLINDTRLSSTIVTDKGVRVGTIEHIMSALSAYGIDNALIELNAPEIPIMDGSSLPFIYLLQDAGVVDQKAQKRFLKILKPVEIKEAGKWVRFTPYDGFKVTLTIEFDHPVFNRSSPTFEIDFAGKSYIDEIARARTFGFMHEVEMMRAHNLGLGGNLNNAIVIDDTDVLNPEGLRYPDEFVRHKILDAIGDLYIVGHPIVGAFEGYKSGHAINNALLRAVLADETAYDRVEFADSDDLPDAFHELNIRTCG
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: MURA_SYNC1
Sequence: MDKIVIHGGNRLKGEVRISGAKNSALPLLFATLLAPGQHQLENVPALRDISTAGKLLSILGAEVHSQEGVFSVDATRIRSVEAPYDLVRTMRASVLVLGPLLARLGHARVSLPGGCAIGARPINLHLKGLEAMGAEIDLDHGYVEARAKRLHGANIYLDIPTVGGTENLLMAACLAQGTTVIENAACEPEIVDLATALTCMGARIEGAGTDRIVVEGVDELQPLHYAVMPDRIEAGTFMVAAAMTRGDVRLLGARQADLEALISKLQEAGVTISAEDHALRVRGPRRIAPVDIKTQPHPGFPTDMQAQFMALMSIADGTSVVTESVFENRFMHVCELQRLGADIAIEGKTAKVRGVKELLGAPVMATDLRASASLVLAGLAAENTTEVSRIYHLDRGYERLEEKFRNLGAHIERIKG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1502_MYCTU
Sequence: MAWRKLGRIFAPSGELDWSRSHAALPVPEWIEGDIFRIYFSGRDGQNRSSIGSVIVDLAVGGKILDIPAEPILRPGARGMFDDCGVSIGSIVRAGDTRLLYYTGWNLAVTVPWKNTIGVAISEAGAPFERWSTFPVVALDERDPFSLSYPWVIQDGGTYRMWYGSNLGWGEGTDEIPHVIRYAQSRDGVHWEKQDRVHIDTSGSDNSAACRPYVVRDAGVYRMWFCARGAKYRIYCATSEDGLTWRQLGKDEGIDVSPDSWDSDMIEYPCVFDHRGQRFMLYSGDGYGRTGFGLAVLEN
What are the official names of this protein?
Uncharacterized protein Rv1502.
Protein: DES_CAPAN
Sequence: MSSYSESPKLPVREIPGDYGFPIISAIKDRYDYFYNQGEDAWFHGKAEKYKSTVVKINMAPGPFTSNDYKLVAFLDATSFVYMFDNTLIDKTDTLGGTFKPGKEYYGGYRPVAFVDTKDPNHAALKGYILSSFAKRHNLFIPLFRNSLSDHLFNDLEKQVSEQGKSDFNALLPNMTFGFIFRLLCDQTNPSDTVLGAQGPEHLRKWLFPQLIPSLSARKLPSFIEDLLFHNFLIPFGFVKSDYQKLVDAFSKSAVSMLDEAEKLGIKREEAVHNMLFLVGINMFAGLNAFFPHLIRFVGEAGPNLHTRLANEIRTAIKEEGGAITLSAINKMSLVKSVVYETLRLRPPVPLQYGKAKKDFMVQSHDASYKINKGQFLVGYNPMASRDPKIFANPDEFVPDRFMGDGEKMLKHVLWSNGRETENPAPENKQCAGKDLVQLLGRLILVEFFMRYDTFTVEITPLFRAPNVAIKTLTKATS
What is the function of this protein?
Involved in the biosynthesis of the anti-fungal toxins colneleic acid and colnelenic acid.
What are the official names of this protein?
9-divinyl ether synthase, StDES, Colneleate synthase, Cytochrome P450 74D4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family. 9-divinyl ether synthase subfamily.
Protein: T11_TERSU
Sequence: MSCFPVLFVMMLLASQSVWAFPEPETRIGTARDAESMGVRSAVEECCENPVCKHTSGCPTTG
What are the official names of this protein?
Teretoxin Tsu1.1.
What is the protein family that this protein belongs to?
Belongs to the teretoxin A (TA) superfamily.
What are the subcellular locations of this protein?
Secreted.