PharMolix/UniProtQA huggingface dataset:
Protein: CMOB_VIBPA
Sequence: MFNFANFYQLIAQDTRLQPWLNVLPQQLTDWQNAEHGDFGRWLKALNKIPEGSPDQVDIKNSVTISNDTPFHEGELKKLENLLRTFHPWRKGPYTVHGIHIDTEWRSDWKWDRVLPHISPLKNRSVLDVGCGNGYHMWRMLGEGARLCVGIDPSHLFLIQFEAIRKLMGGDQRAHLLPLGIEQLPKLEAFDTVFSMGVLYHRRSPLDHLIQLKDQLVSGGELVLETLVIEGDENAVLVPTSRYAQMRNVYFFPSAKALKVWLELVGFEDVHIVDENVTSVDEQRTTDWMTHNSLPDYLDPNDPSKTVEGYPAPRRAVLVARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: HASC2_STRPQ
Sequence: MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIRQSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATIAVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIFSILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKHPQVKDDLKAYIIQLGKALEKTKP
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase 2, Alpha-D-glucosyl-1-phosphate uridylyltransferase 2, UDP-glucose pyrophosphorylase 2, UDPGP 2, Uridine diphosphoglucose pyrophosphorylase 2.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: ARF1_BRARP
Sequence: MGILFTRMFSSVFGNKEARILVLGLDNAGKTTILYRLQMGEVVSTIPTIGFNVETVQYNNIKFQVWDLGGQTSIRPYWRCYFPNTQAVIYVVDSSDTDRIGVAKEEFHAILEEEELKGAVVLIFANKQDLPGALDDAAVTEALELHKIKSRQWAIFKTCAVKGEGLFEGLDWLSNTLKSGSG
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: PDXT_STAA3
Sequence: MKIGVLALQGAVREHIRHIELSGHEGIAVKKVEQLEEIEGLILPGGESTTLRRLMNLYGFKEALQNSTLPMFGTCAGLIVLAQDIVGEEGYLNKLNITVQRNSFGRQVDSFETELDIKGIATDIEGVFIRAPHIEKVGQGVDILCKVNEKIVAVQQGKYLGVSFHPELTDDYRVTDYFINHIVKKA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SYFA_LACAC
Sequence: MDLFDKLKELHEEGLKQISKATDEKTLNEVRVELVGRKGELTKILHSMRDVAPENRREVGQKVNELRDLFNAQLDEAKENIVKAVLAKRLEEEKIDVTLPGREGHLGSKHPINIILDDLESYFIGMGYKVVQGPEIETDHYVFEMMNLPKDHPARDMQATFYINDENLLRSQTSGDQARVLEKHDFSKGPLKMVGPGKVYRRDDDDATHSHQFMQMEGLVIDKHVTMSDLKGTLEMIAKHVFGQDRATRLRPSYFPFTEPSVEMDVSCFNCDGKGCPICKYTGWIEVLGAGMVHPNVLENAGVDSNVYGGFAFGVGLDRFAILKYGIDDIRDFYTNDVRFLEQFRKEEK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATRX_LNYV3
Sequence: MSAKLNWYRITFNDTVWRFDTARGPKDGETCPLIASELFSSGLSEVFKSVTSFSEILRNMESRGYITNITLRADSDILGPGALRCEFLFPSEVFIPTSHTLKMGRSSLILEPHLVVLKECKYISSGKLDIGISSIEATSVAVLRRVKGPAFIGCMDDNPFGVLTKKPSDEKNVLASK
What is the function of this protein?
Plays a major role in assembly and budding of virion.  Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form.  Inhibits viral transcription and stimulates replication (By similarity).
What are the official names of this protein?
Matrix protein.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host endomembrane system; Peripheral membrane protein.
Protein: WDR43_HUMAN
Sequence: MAAGGGGSCDPLAPAGVPCAFSPHSQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAVHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFEHILNGYCKKPLTSNCTIQIATPGKGKKSTPKPIPILAAGFCSDKMSLLLVYGSWFQPTIERVALNSREPHMCLVRDISNCWAPKVETAITKVRTPVMNSEAKVLVPGIPGHHAAIKPAPPQTEQVESKRKSGGNEVSIEERLGAMDIDTHKKGKEDLQTNSFPVLLTQGLESNDFEMLNKVLQTRNVNLIKKTVLRMPLHTIIPLLQELTKRLQGHPNSAVLMVQWLKCVLTVHASYLSTLPDLVPQLGTLYQLMESRVKTFQKLSHLHGKLILLITQVTASEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE
What is the function of this protein?
Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis (PubMed:17699751).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I (PubMed:17699751, PubMed:34516797).  Essential for stem cell pluripotency and embryonic development.  In the nucleoplasm, recruited by promoter-associated/nascent transcripts and transcription to active promoters where it facilitates releases of elongation factor P-TEFb and paused RNA polymerase II to allow transcription elongation and maintain high-level expression of its targets genes (By similarity).
What are the official names of this protein?
WD repeat-containing protein 43, U3 small nucleolar RNA-associated protein 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the UTP5 family.
Protein: C330_FUNHE
Sequence: MGYFYLTAETWTLLVAFVTLLLVYAYWPYGTFKRLGISGPKPVPFFGTMLHYRRGFFTFDEECKKKYGKVWGIYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNFRLNGPLYDAVSIAEDDQWKRIRSVLSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKDEPLDLKEFFGSYSMDVVTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLAVAFFPFLGPILEKFELSFFPKSVTDFFYASLEKIKSNREASQQKSRVDFLQLMIDSQKNSGAQQDKSLTDHEILSQSMIFIFAGYETSSSSLTFLAYNLATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAAVEINGVVIPKDMVVMIPTWPLHRDPEIWPEPEAFKPERFSKKNKDNIDPYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQYSFSVCKETEVPFEMDIQGLLAPKRPIQLKLVPRS
What is the function of this protein?
Putative steroid 6-beta-hydroxylase.
What are the official names of this protein?
Cytochrome P450 3A30, CYPIIIA30.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: NUOI_WOLSU
Sequence: MDLKQKYIFIEGTNCPVTVRGRLLQVFRRSVSGELFKGLWLVLREMLRFNIHTTQYPKEKLPLSPRYRAIHELLRLLESGNERCIGCGLCEKICISNCIRMETSYGEDGRKKVHEYTINFGRCIFCGFCAEVCPELAIVHGGRYENASEQRAHFGLKEDMLTPMERFMNQGQKEFPGFGALSQDADSKVKKTPLAYFTPKGEENV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NC2A_MOUSE
Sequence: MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHVDGDKGPRRGRKPGSSGRKNGGTGSKGKDKKLSGTDSEQEDESEDTDTDGEEETPQLPPQASHPPAHFQSPPTPFIPFTSPLPLPPAPPGPSAADAEDEEDYDS
What is the function of this protein?
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes.  This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP.  Can bind to DNA on its own (By similarity).
What are the official names of this protein?
Dr1-associated corepressor, Dr1-associated protein 1, Negative cofactor 2-alpha, NC2-alpha.
What is the protein family that this protein belongs to?
Belongs to the NC2 alpha/DRAP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCPY_PSETP
Sequence: MDKRFYSFFNLTEDQAIAILDTPQDQIGEDDSRYIAASHLVNFNSERSIAALMRAIHHTDPEMENRIVRRKAVETLGRLRATVALPVIRECLSDPDCYMIENAVWAIGEIGTEDPEILQEIMLLLDRSEQTYRVIIQTLAKLDYKPAIAKIKPFTTDESLPISSAAITALCRLNRDFSQMDQIVTLLQNRNVIARRLSIQDLIDANYYAAIPDISRCPVSLVFRLRGIGMLSEAGIQEGAIAFVDIQPYLEKSLIDHPSSLSLVHSYDTLPDLSFLIHELYETDFGRCYTAIKTILENYAESAPEALFNTYEQEAKNDYGAHFHVMKLFPWLRHAPAYNLLIEALHNKQPQFQKSRAAAAIALAEIGDPRAIPEIKSCLTAQIWDLKYASLLALEKFGDRSGYELLANDDDLLIREKRNS
What are the official names of this protein?
Uncharacterized phycocyanin operon protein Y, ORF Y.
Protein: PPARA_CAVPO
Sequence: MVDMESPLCPLSPLEAEDLESPLSEYFLQEMGTIQDISRSLGEDSSGSFGFPEYQYLGSGPGSDGSVITDTLSPASSPSSVSYPEVPCGVDEPPSSALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEVLTCDRDSEGAETADLKSLAKRIYEAYLKNFHMNKVKARIILAGKTSSHPLFVIHDMETLCTAEKTLMAKVVSDGIRDKEAEVRIFHCCQCVSVETVTNLTEFAKAIPGFASLDLNDQVTLLKYGVYEAIFTMLSSTMNKDGMLVAYGHGFITREFLKNLRKPFCDMMEPKFNFAMKFNALELDDSDISLFVAAIICCGDRPGLLNIDHIEKMQEAIVHVLKLHLQSNHPDDTFLFPKLLQKLADLRQLVTEHAQLVQVIKTESDAALHPLLQEIYRDMY
What is the function of this protein?
Ligand-activated transcription factor.  Key regulator of lipid metabolism.  Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC).  Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety.  Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids.  Regulates the peroxisomal beta-oxidation pathway of fatty acids.  Functions as transcription activator for the ACOX1 and P450 genes.  Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.  May be required for the propagation of clock information to metabolic pathways regulated by PER2 (By similarity).
What are the official names of this protein?
Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS51_VIBVY
Sequence: MTEQKVVIIDTGCANVSSVKFAIERLGYDVTISKDPQVVLSADKLFLPGVGTASEAMKNLEERDLISLVKQVEKPLLGICLGMQLLGKVSQEKGQKADELVECLGLCDGEVKLLQTGDLPLPHMGWNTVSAKAGNPLFKGIEEGEYFYFVHSFAMPVGDYTIAECEYGNSFTAAVQSGNYYGVQFHPERSSKAGAKLIQNFLEL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH 1, IGP synthase glutaminase subunit 1, IGP synthase subunit HisH 1, ImGP synthase subunit HisH 1, IGPS subunit HisH 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1A1D_VARPS
Sequence: MNLKKFPRHALTFGPTPIHPLKRLSAHLGGEVELYAKREDCNSGLAFGGNKTRKLEYLIPEALEGGYDTLVSIGGIQSNQTRQVAAVAAHLGLKCVLVQENWVNYSDAVYDRVGNIEMSRIMGADVRLDSAGFDIGIRKSWEEAMADVRKAGGKPFPIPAGCSEHPRGGLGFVGFAEEVRQQEAELGFKFDYIVTCSVTGSTQAGMVVGFAADGRADRVIGIDASAKPEQTFAQIVRIAKGTAELVELGRDITDKDVVLDRRFGGPEYGLPNEGTLESIRLCARLEGMLTDPVYEGKSMHGMIEKVRLGEFPAGSKVLYAHLGGVPALNAYSFLFRNG
What is the function of this protein?
Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.  Allows growth on ACC as a nitrogen source.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate deaminase, ACC deaminase, ACCD.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: YG1D_SCHPO
Sequence: MSKIEKKQASASNLLLGAGLNLFETSSLGQPLEVTKVQMAANRTQTMAQAIKAIMSRGGILGFYQGLIPWAWIEASTKGAVLLFTSAELEYWGRRLGLGATSAGAIAGMGGGVAQAYATMGFCTCMKTAEVTRAKQAATGQEVKGTFRVFADLYKEKGIRGINRGVNAVALRQMTNWGSRLALSRFLEKPIRYFTGRTEAEPLTTGQRFVASVSAGALSCWNQPLEVARVEMQSLTKGIQHSSPGIMQTIMSIYKNNGIKGLYRGAVPRMGLGAYQTFVMVFLADCVRGYLAK
What are the official names of this protein?
Uncharacterized mitochondrial carrier C83.13.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ALF1_HALSA
Sequence: MRPFEDSPISRDGKVLILAYDHGLEHGPVDFEAVPATKDPEAVWDVATHDAVSAMAAQKGIAEAYYPSYSDDVNLLAKLNGTSNLWMGEPDSAVNWTVDYAADVGADAVGFTLYGGSNSEVEMAEEFRDAQEAARDHDLPVVMWSYPRGQGLKNDKNPDTIAYAARQALELGADIAKVKYPGSTDAMSHAVDMAGPTNVVMSGGSKTSDRDFLESVKGAIDAGASGLAVGRNVWQREHPAAFLDGLEAVVYEEASVDEALGRI
What is the function of this protein?
Has aldolase activity with fructose 1,6-bisphosphate.  May play a role in the biosynthesis of aromatic amino acids (AroAA).
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
Protein: RPOZ_SHESW
Sequence: MARVTVEDAVEQIGNRFDMILVAARRARQIAVQGKDPMVEEMNDKPTVIALREIELGLVNAHTLDADERQTVREREAAEIAAVAAIAEGRSL
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RS27_CAEEL
Sequence: MPLAVDLLHPEPQREIRCHKLKRLVQHPNSYFMDVKCSGCFKISTVFSHATTVVVCVGCNTVLCQPTRGKAKLTEGCSFRKKQ
What are the official names of this protein?
40S ribosomal protein S27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: RS10_METPP
Sequence: MQKQKIRIRLKAFDYKLIDQSALEIVDTAKRTGAIVKGPVPLPTRMQRFDILRSPHVNKSSRDQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DLTA_STRA5
Sequence: MIHDMIKTIEHFAETQADFPVYDILGEVHTYGQLKVDSDSLAAHIDSLGLVEKSPVLVFGGQEYEMLATFVALTKSGHAYIPVDQHSALDRIQAIMTVAQPSLIISIGEFPLEVDNVPILDVSQVSAIFEEKTPYEVTHSVKGDDNYYIIFTSGTTGLPKGVQISHDNLLSFTNWMISDDEFSVPERPQMLAQPPYSFDLSVMYWAPTLAMGGTLFALPKTVVNDFKKLFATINELPIQVWTSTPSFADMALLSNDFNSETLPQLTHFYFDGEELTVKTAQKLRQRFPKARIVNAYGPTEATVALSAVAITDEMLETCKRLPIGYTKDDSPTYVIDEEGHKLPNGEQGEIIIAGPAVSKGYLNNPEKTAEAFFQFEGLPAYHTGDLGSMTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSQYVKSAVAVPRYNKDHKVQNLLAYIVLKEGVRDDFERDLDLTKAIKEDLKDIMMDYMMPSKFIYREDLPLTPNGKIDIKGLMSEVNK
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACB_STAAT
Sequence: MKIALGCDHIVTDTKMRVSEFLKSKGHEVIDVGTYDFTRTHYPIFGKKVGEQVVSGNADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNANVIGFGGRIIGELLMCDIIDAFINAEYKPTEENKKLIAKIKHLETSNADQADPHFFDEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: HFQ_ALISL
Sequence: MAKGQSLQDPFLNALRCERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARAVSHHTASDRPQGERPQETTEE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CIC1_YEAST
Sequence: MAKKSNSKKSTPVSTPSKEKKKVIEKKSSTAIPRERVIKAVNELIKFTSKPQDENNEEGNNGKKNLLEDDEEELKKDLQLIVVNNKSFTGTSKSFKLKLLNVKHSFYKPWKEASATAVKDFKVLLILKDSDIKKVSEDDLFDQLDSEGIKVDEIICGKDLKTVYKAYEARNAFISQFSLILADDSIVTSLPKLMGGKAYNKVETTPISIRTHANKEFSLTTLTNNIKKVYMNQLPVKLPRGTTLNVHLGNLEWLRPEEFVDNVELISEQLIKAYQIRSIFIKTNRSPVLPLYYNQDVLDELEAKKDKIEETHEDDMVTIDGVQVHLSTFNKGLMEIANPSELGSIFSKQINNAKKRSSSELEKESSESEAVKKAKS
What is the function of this protein?
An adapter protein that specifically links the 26S proteasome to its substrate CDC4 which is one of the substrate recognition subunits of the SCF E3 ubiquitin ligase complex.  Required for turnover of cell cycle regulatory proteins CDC4 and GRR1.  Required for synthesis and nuclear export of 60S ribosomal subunits.  Required for vegetative growth.
What are the official names of this protein?
Proteasome-interacting protein CIC1, Core interacting component 1.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: COQ4_ANOGA
Sequence: MFVRKSCYSLINATRRCLRYRQLSSTTAGTVGTTAPTANISLNDEPQPAAAEMDEFTKEFLRNRIEVSDIQRLILSAGSSVAALVDPRRHDMIACLGETTGREALEKILHYMRSTEEGQRILVEKPRINTRTVDMEALKKMPEHTFGYTYVKFMEDNNITPDSRMEVRFLDEPGLAYVMTRYRETHDMVHAILDMPTNMLGEVTVKWVEALNTGLPMCYGGAVFGAFRLRTKQRQNYLRKYLPWALRTGNRIKPLMGVYWEKRWEQDVTELRKELNIELLAP
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL21_ECO5E
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ENO_NATTJ
Sequence: MSMIEEIYAREIFDSRGNPTVEVELYTESGAYGFARVPSGASTGVHEALELRDGEDRFGGKGVRKACSKVNEEIGPNLVGMDVTFQSAIDRALLELDGTDNKENLGANAMLGVSLAAARASAEFLGLPLYQVLGGVSSSTLPIPQMNILNGGEHADNNVDIQEFMIMPIRANNFQHAMRMGVEIFHALKNVLKDEGLSTSVGDEGGFAPDLKSNKEALEYIITAIEKVGYKPGEQVMLAIDAAASELYQGDKYHLEGEGKSLTADEMIDLYQDLVENYPIISIEDGLSEDDWEGWKKMTEKFQGKIQLVGDDLFVTNTDRLTRGIKEDIANSILIKLNQIGTVTETLEAIELAKKNGYTSVISHRSGETDDPFIADLAVATNAGQIKTGAPSRMDRVAKYNQLIRISEELYGVSRYPGMGSFYNLEV
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL6_BURTA
Sequence: MSRVGKSPIALQGAEVKLADGSITVKGPLGTITQAVNPLVNVANNDGTLNLSPVDDSREANALSGTMRAIIANMVQGVTKGFERKLTLVGVGYRAQAQGDKLNLSLGFSHPVVHQMPEGIKAETPTQTEIVIKGIDKQKVGQVAAEVRGYRPPEPYKGKGVRYADEVVILKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CATH_PIG
Sequence: MWAVLSLLCAGAWLLGPPACGASNLAVSSFEKLHFKSWMVQHQKKYSLEEYHHRLQVFVSNWRKINAHNAGNHTFKLGLNQFSDMSFDEIRHKYLWSEPQNCSATKGNYLRGTGPYPPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMNDEEAMVEAVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
What is the function of this protein?
Important for the overall degradation of proteins in lysosomes.
What are the official names of this protein?
Pro-cathepsin H.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: MNMC_CHRVO
Sequence: MTHSHAQLVWQDGQPMSAVFGDVYFSRASGLEETRHVFLRHNQLEERFAALPPSGSFAIAETGFGTGLNFLCAWQCFEARAPAGARLHFVSAEKFPLTPSDLAQALALWPELEPWSSQLLAQYDVLTPGWHRFVLAGGRVTLTLMIGDVLEVLPQLDARVDAWFLDGFAPSKNPDMWQQALFEQMARLSGPGASFATFTSAGAVRRGLAGAGFEVRKAPGHGAKRHISHGWIATPPDAGWQAPWYARPEPRWRERSAIVVGGGLAGAASARSLALRGWQVTLIERMPQLASAASGNPQGVLYTKLSPHLTPLTRLVLSGYAYSLRALRCLLPEDGDWQACGVLQLAHDGKEAEKQQALAELNLPESVMRPLDRDAASELAGTDLPCGGLFFPQGGWVHPPALVRQLADHPNIVIKTGRTALTLDYDPAQRSWTAGDEQGPLAVASVVVLAGAAETAQFDSTRHLPLKKIRGQITSIPASEESSRLRTVLCGEGYISPARGGRHCLGATFKFDTDDLGVNDGEHAENLAMLAELAPSLRASLDRDAPEHLDGRAAFRCTSPDYLPLVGPAVAARDFVHAYRELARDATLRPATACPWAEGLYVNAAHGSRGLITAPLSGEILASLLEGEPAPLPADLMRAVHPSRFLLRDLIRRKLDPDAL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.