PharMolix/UniProtQA huggingface dataset:
Protein: FLRT3_PONAB
Sequence: MISPAWSIFLIGTKIGLFLQVAPLSVMAKSCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELRLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRIPTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGMAIKDLNAELFDCKDSGIVSTIQITTAIPNTVYPAQEQWPAPVTKQPDIKNPKLTKDHQTTGSPSRKTITITVKSVTSDTIHISWKLALPMTALRLSWLKLGHSPAFGSITETIVTGERSEYLVTALEPDSPYKVCMVPMETSNLYLFDETPVCIETETAPLRMYNPTTTLNREQEKEPYKNPNLPLAAIIGGAVALVTIALLALVCWYVHRNGSLFSRNCAYSKGRRRKDDYAEAGTKKDNSILEIRETSFQMLPISNEPISKEEFVIHTIFPPNGMNLYKNNHSESSSNRSYRDSGIPDSDHSHS
What is the function of this protein?
Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners.  Plays a role in the spatial organization of brain neurons.  Plays a role in vascular development in the retina (By similarity).  Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (By similarity).  Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1.  Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity).  Promotes neurite outgrowth (in vitro).  Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length.  Plays a role in the regulation of the density of glutamaergic synapses.  Plays a role in fibroblast growth factor-mediated signaling cascades.  Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning.  Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development.  Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity).
What are the official names of this protein?
Leucine-rich repeat transmembrane protein FLRT3, Fibronectin-like domain-containing leucine-rich transmembrane protein 3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane. Cell junction, focal adhesion. Secreted. Cell projection, axon. Cell projection, growth cone membrane. Note=Detected on dendritic punctae that colocalize in part with glutamaergic synapses, but not with GABAergic synapses. Proteolytic cleavage in the juxtamembrane region gives rise to a shedded ectodomain.
Protein: SELA_CLOB6
Sequence: MDKKQLLRNLPKIDELLKEEIINRYLQENSRTLVVDSLRQSIDHYRGEILKNNIDSFTRENVVNYFIDTLEENKSTKFKKVINATGVVIHTNLGRSLLAKEAIENVVKVSENYSNLEYDLRKGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALNTLCEEREAIVSRGQLVEIGGSFRVPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSEEMVQLGEKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQAGIIVGKKKYIDKMKKNQLTRALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKDIHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGERIPTYVVKVNSDKITAEKIEEKLRLSKDPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETXG_STAAM
Sequence: MKKLSTVIIILILEIVFHNMNYVNAQPDPKLDELNKVSDYKNNKGTMGNVMNLYTSPPVEGRGVINSRQFLSHDLIFPIEYKSYNEVKTELENTELANNYKDKKVDIFGVPYFYTCIIPKSEPDINQNFGGCCMYGGLTFNSSENERDKLITVQVTIDNRQSLGFTITTNKNMVTIQELDYKARHWLTKEKKLYEFDGSAFESGYIKFTEKNNTSFWFDLFPKKELVPFVPYKFLNIYGDNKVVDSKSIKMEVFLNTH
What is the function of this protein?
Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome.  The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.
What are the official names of this protein?
Enterotoxin type G, SEG.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal/streptococcal toxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS5_RALSO
Sequence: MTTIAIVDYGMGNLRSVAQALSTVAPDADVRISAQADEIRAADRVVLPGQGAMPDCMAAFDQSGLREAVLEAARTKPMLGVCVGEQMLLERSAEARAGEAFTAGLGLISGDVIRFDLDGRLQPDGSRYKVPQMGWNRVHQSRTHALWAGVPDQSYFYFVHSYYARPAHPDESVGETEYGVRFTCAIARDNIFATQFHPEKSAQAGLQIYRNFVHWKP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_RHIME
Sequence: MTRKIMLQGTGSDVGKSVLVAGLCRLASNHGLSVKPFKPQNMSNNAAVADDGGEIGRAQWLQALAARVPSSVHMNPVLLKPQTDVGSQVVVQGRVAGQAKGKEYQALKPSLLGSVMESFEQVSAGADLVIVEGAGSPAEINLRAGDIANMGFATRADVPVVLVGDIDRGGVIASLVGTHAILPGDDRRMVTGYLINKFRGDVTLFDDGIASVRQFTGWPCFGVVPWLKSAGRLPAEDSVVLERLTRGGGKALKVAVPVLSRIANFDDLDPLAAEPDVDIVFVRPGTPLPDDAGLIVIPGSKSTIADLDDFRRQGWDRDLDRHMRRGGRVVGICGGYQMLGSRVADPLGIEGGKREIEGLGLLSVETEMAPEKTVRNSRAWSREYDVALEGYEIHLGKTTGADCSRAPVEIDGRPDGAMSADGRVMGTYLHGLFGSDAYRSALLKSFGIEGGGGNYRRSVDAALDEIALELETVLDRAWLGTLLG
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: K1C12_RABIT
Sequence: DHDYEFPGIQAFAGLGMGFGGSPGGGSLYLPSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEDANAELENKIREWYEARGHGHGDCGPQHDYSKYHPLIEDLRNKIISASIGNAQLILQIDNARLAADDFRMKFENEAALRQTVEADINGLRRVLDELTLARADLEAQIESLTEELAYMKKNHEEELQSCRAGGPGEVSVEMDAAPGVDLTRLLNDMRAQYEAIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRALQNLEIELQSQLAMKKSLEDSLAETEGDYCGQLSQVQQLVGDLEAQLQQVRSDTERQNMDYQRLLNVKARLELEIETYRRLLDGEAQGDGLDESSAMTGSRSQAQSIDSSKDPSKTRKIKTIVQEVVNGEVVSSQVQEIQN
What is the function of this protein?
Involved in corneal epithelium organization, integrity and corneal keratin expression.
What are the official names of this protein?
Keratin, type I cytoskeletal 12, Cytokeratin-12, CK-12, Keratin-12, K12.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RL13_METRJ
Sequence: MKTTSLKPAEVDKKWIVIDAEGLVVGRLASIVAMRLRGKHKAAYTPHVDCGDNVIVINAEKVKFTGRKYNQKSYFYHTGYPGGIKERTAKFILEGRFPERVVEKAVERMLPRGPLFRQILGNLRVYKGTEHPHEAQQPQALDVGALNRKNVSA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: QUEC1_COLP3
Sequence: MAEKVVVIYSGGMDSFTVLNRAKKDGKEVFALSFDYGQRHVKELECASIVCKELAVNHKVIDISAINQLLAGSSLTDDIDIPEGHYEAESMKSTVVPNRNMILLSLAVAYAVSVGAEQVYYGAHSGDHAIYPDCRPEFVEKMNDVCKIANYESVEIFSPYLSVDKTAILADGIKMGLDYSNTWTCYNGREKACGKCGSCQERLEAFEENNATDPIPYE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase 1, 7-cyano-7-carbaguanine synthase 1, PreQ(0) synthase 1, Queuosine biosynthesis protein QueC 1.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: YNHF_ECOL5
Sequence: MSTDLKFSLVTTIIVLGLIVAVGLTAALH
What are the official names of this protein?
Uncharacterized protein YnhF.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: VKT2L_HETCR
Sequence: GSTCLEPKVVGPCKA
What is the function of this protein?
This recombinant serine protease inhibitor inhibits both trypsin (Ki=2. 5 nM) and chymotrypsin (Ki=30 nM) (PubMed:17447883).  It may also inhibit the TRPV1 receptor, a receptor of the pain pathway (By similarity).  In vivo, shows anti-histamine activity, since it dose-dependently weakens the clinical manifestation of the allergic reaction induced by histamine injection.  In vivo, does not show toxicity to mice by intraperitoneal injection (PubMed:17447883).
What are the official names of this protein?
PI-stichotoxin-Hcr2l, PI-SHTX-Hcr2l, Kunitz-type serine protease inhibitor RmIn II.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: DAPA_PROM4
Sequence: MSSAAHLSPKPFGRLLTAMVTPFDSDGKVDYAIAGRLARYLVDEGSDGIVVCGTTGESPTLSWSEQHQLLETVKSSVGKAVKVLAGTGSNSTAEAIEATVKAAELGADGALVVVPYYNKPPQEGLEIHFRSIANAAPDLPLMLYNIPGRTGSSIHPATVKRLMNCPNIISYKAASGTTSEVTDLRMQCGSQLAVYSGDDGLLLPMMSVGAVGVVSVASHIVGSRIKAMIDAYSTGQVNIALAYHEQLQPLFRALFATTNPIPVKAALEAIGWQVGSPRRPLSPLKKQMKEDLIDIIKSLRQI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THI42_SORBI
Sequence: MATTASSLLKSSFAGARLPASTRTPSSPAVVATPRGAGAIRASSISSSNPPYDLTSFRFSPIKESVVSREMTRRYMTDMITYADTDVVIVGAGSAGLSCAYELSKDPSVSIAIVEQSVSPGGGAWLGGQLFSAMVVRKPAHLFLDELGVAYDEAEDYVVIKHAALFTSTVMSRLLARPNVKLFNAVAVEDLIVKGGRVGGVVTNWALVSMNHDTQSCMDPNVMEAKVVVSSCGHDGPFGATGVKRLQDIGMISDVPGMKALDMNTAEDEIVRLTREVVPGMIVTGMEVAEIDGAPRMGPTFGAMMISGQKAAHLALKALGRPNAVDGTIKVVSPALRQEFVIASKDDEVVDA
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase 2, chloroplastic, Thiazole biosynthetic enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1931_PECCP
Sequence: MIAGMPALTHKQQQDAVERIQELMSEGMSSGQAIAQVAAEIRQEHQGDNVAVMFDEDDDTVNDSDEEHYFDDGEEEDEQ
What are the official names of this protein?
UPF0181 protein PC1_1931.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: RSMH_PHOPR
Sequence: MSEQFEHISVLLHESVDGLAIKPDGIYIDGTFGRGGHSRLILSHLGENGRLYGIDRDPQAIAEAQTIDDPRFSIIHGPFSGMAQYMEERDLIGRVDGVLLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTSGISAAEWLAEAEADDIAWVLKEFGEERFAKRIARGIVEHRENPDKKPLTRTKELAALISDVSPFRDKHKHPATRSFQAIRIYINSELDEIETALNGAVKVLAPQGRLSVISFHSLEDRMVKRFIRKNSKGPEVPAGFPLTEDQIKALGSADLKMASKAIKPSKDELGDNKRARSSVLRLAERL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO1C_SULIK
Sequence: MIDEKDKSYLEEKVKQASNILPQKIVEDLKNLISNKEVLVTRDEIDKIFDLAIKEYSEGLIAPGEAIGIVAAQSVGEPGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTPMMTIYLTDEYKHDKEKALEVARKLEYTKIENVVSSTSIDIASMSIILQLDNEMLKDKGVTVDDVKKAINRLKLGEFVIDESEGNTLNISFANIDSIAALFKLRDKILNTKIKGIKGIKRAIVQKKGDEYIILTDGSNLSGVLSVKGVDIAKVETNNIREIEEVFGIEAAREIIIREISKVLAEQGLDVDMRHILLVADVMTRTGVVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAARGDVEEFKGVVENIIIGHPIKLGTGMVELTMRPILR
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Forms part of the jaw domain.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo1C, DNA-directed RNA polymerase subunit A''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PX11A_MOUSE
Sequence: MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKADKEAVVLKLKRLETSVSTGRKWFRLGNVFHAIQATEQSIQAADLAPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGVNREKWQRWAARHYYYFLLLSLVRDLYEILLQMGQVARDRAKREKSSRDPPKYSVANEETEWLQSFLLLLFQSLKRHPPLLLDTVKNFCDILIPLNQLGIYKSNLGVVGLGGLISSLAGLLTVVYPQLKLKAR
What is the function of this protein?
May be involved in peroxisomal proliferation and may regulate peroxisomes division.  May mediate binding of coatomer proteins to the peroxisomal membrane (By similarity).  Promotes membrane protrusion and elongation on the peroxisomal surface.
What are the official names of this protein?
Peroxisomal membrane protein 11A, Peroxin-11A, Peroxisomal biogenesis factor 11A, Protein PEX11 homolog alpha, PEX11-alpha.
What is the protein family that this protein belongs to?
Belongs to the peroxin-11 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: MINE_SHEPW
Sequence: MSLLDYFKTKKKPSTAATAKERLQIIVAHQRGERDAPDYFPQMKQEIIEVIRKYVKVGADQVSVQLDQNDDNLSVLELNVTLPEQS
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RPOZ_FRATF
Sequence: MARVTVEDCLDKVETRFDLVVLASMRANKILKNGYSESMENEKKEKATVVALREIAESEITPEQILRNEIEG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: LMUA_BACC8
Sequence: MDISSYPSLETYEARENTGSRSSNRLAMQISFAMWKIFELYQNEDFTVAMDCIDDVVIFKTSNENPTIVTYQLKTKDATTGNFELRKLIGDNVFLKMYDHIEKIDADVEEIYLITNNPLKFRKKTVNAERILFEKLDEDIKELIEENMSQSKVFADKGLSSKFIYSLVDMSFHNHREISQYKLNSLLMKEKIDISITAADALFNALQDILTTKQNYEFSLQDEFNTVLKKKSYSKTEFTSLLDNSKKINAYVLSFEDIRTNYKSKPLKLKEESLYRRAMASVKEKCNKSPNILQNINEDIFQYAKEQIDINDEITRIELVILLQSVFDDKINVELSKEEKEILYMQNIELALREG
What is the function of this protein?
Component of antiviral defense system Lamassu type II, composed of LmuA and LmuB.  Expression of Lamassu type II in B. subtilis (strain BEST7003) confers resistance to phage SpBeta (PubMed:29371424).  May be a nuclease (Probable).
What are the official names of this protein?
Lamassu protein LmuA, Putative nuclease LmuA.
Protein: RF1_ANAMF
Sequence: MSFEDSLEGLCEKFRILKQQLSDPESLGVQAFVVASREYSDLLPIMSLIEEYQTAQKEIEELEGLINSTDTDAELVHLAREELYTKQKLIPKLKHQLQLSLLPKDKDDSRSAILEIRAGTGGEEAALFVCDLYRMYIKYAERKSWKVEPIGISTTGIGGYKEASLCIGGKDVFARLKFESGVHRVQRVPETESSGRLHTSAATVAVLPEVEEVDLKIDEKDLRIDVYRSSGPGGQSVNTTDSAVRITHIPTGIVVIQQDEKSQHKNKSKALKVLRARLYNLEKQKIEDEISKMRKSQIGSGDRSERIRTYNFLQSRITDHRINMTLYRLEHIMKEGDLDEFVDALIADDQANKLQQISS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAK14_ORYSJ
Sequence: METRSGGSGSASGGGGGGRMRLRKTESAEMRWVVSGGAYEEDEIESSDGGGGTPAAASGSRGGCSDSDDNYEEAEMLRQRLVRTGPRADSLDVEAQDVAGMNRHQEITVGRSIVLAVQTLGVVFGDVGTSPLYAFDVMFNKYPITSKEDVLGALSLVIYTLILIPLLKYTLIALWGNDDGEGGTFALYSLICRNARVSLLPNQLRSDTRISSFQLQVPSVELERSLKIKERLETSSMLKKLLLMLVLFGTSMVIADGVVTPAMSVMSAVNGLKVGISSVNEGEVVMITVAVLIVLFTLQRFGSSKVALAVGPALFIWFCCLAGIGIYNMKTYGSAVLQAFNPMYIYYYFERNPTQAWMSLGGCLLCATGSEAMFADLCYFSVKSVQLTFVFLVLPCLLLGYLGQAAFLMENLTENQQVFFLSIPNQAFWPVVFIAILAAIIASRTMTTAIFSTIKQATALGCFPRLKIIHTSRSFMGQIYIPMMNWFLLVSCLAFVTMFGSINEIGNAYGIAELGVMMMTTVLVTIIMLLIWQINIIVVLCFLTLSLGLELIFFSSVLGSVADGSWVLLVFAAVLYLIMYIWNYGTKLKYETEVKQKLSMDLLMELGCNLGTVRVPGIGLLYNELARGVPGIFGQFLATMPAIHSMIIFVCIKWVPVPVVPQNERFLFRRVCPKSYHMFRCIARYGYKDIRKEDYISFQQLLIESLEKFMRREAQERSLESDQYDGTDSEEEVASASSRALVGPNGSINSLGVPPAEAAGTTEHPTIGSSMSFDGSLDEAIDGRGSLDDELSFIHKAKESGVVYLLGHGDIRARKESFFVKKLVINYFYAFLRRNCRRGIAALSIPPSRMMQVAMQYMV
What is the function of this protein?
High-affinity potassium transporter.
What are the official names of this protein?
Probable potassium transporter 14, OsHAK14.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CYCL_WDSV
Sequence: MDIPVEFLTAQEPLSYGHIPPVYWKELLNWIDRILTHNQATPNTWEATHMVLLKLHGTLSFSNPAQLPLVAAACLQIAAKHTEAHSRLADPDYITMLGDGVYTKPSLLLTETMALFIVGGHVGAYTLAACDWLLGSLPFSQAENDLLHPYMYHYIKLSYRHRTPDYHSSPALRAAVVIAAAVKGADLLEMNMLFIMMYHLTHISTASLSLGLTHFTAALQRQINLDFAEAEQREAAERRALLEREREQQLQEARERLDDVMAVLEAEVAITITTATEGTDAEDTSEVDVINVVDPIG
What is the function of this protein?
Transforming protein which induces the development of dermal sarcomas.  Induces positive and negative regulation of transcription from host and viral promoters by interacting with various cellular factors involved in protein transcription regulation.
What are the official names of this protein?
Retroviral cyclin, Rv-cyclin, ORF-A protein.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
What are the subcellular locations of this protein?
Host nucleus. Note=Concentrated in interchromatin granule clusters and perichromatin fibrils.
Protein: SYDP_SHESW
Sequence: MSCLPALDKFLQNYHQAYLTTLGELPRYYPQGEPSVCIQGEFFADSDKPIAWQPVKRDEVGSFTNVEHALDLPLWPDIHLFYGQYFSAPLLFDSKWGTGELLQVWNDDDFKCLQQNVIGHLMMKKKLKQPPTWFIGLLDEGDKMLTINNSDGSVWIEIPGEEQSEQLSTSLTAFIEALSPRIAPPVKHEELPMPALDHPGIFANIKRMWQNLFGKG
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: SYT_WOLPP
Sequence: MIKVTFLAEQKVKEYSGRVTGFDILQPDALREAIAFKVNGELYDLSREIESDTEIEVIQLSDEAGLDIIRHDAAHIMAQAVKELFPNTQITIGPTIQDGFYYDFATDRTFTTDDLAAIEKKMKEIIKSNHRFVREVWTRKQAIDFFSDIGERYKVDIVSSIPENENLTVYKQGNFVDLCRGPHSPSTGRVKAFKLMKVAGAYWRGDSKGPMLQRIYGTAWRNKDELNTYLKRLEEAEKRDHRKIAKDMDLFHIQEEAVGQIFWHEQGYTLYNVLESYIRKKLMNNGYFEVKTPILVSKELWEKSGHWDKFRENMFIIDESESKKLAIKPMNCPCHVQIFNSHIRSYRDLPIRMAEFGTCHRNESSGSLHGLMRVRGFTQDDAHIFCMEKQVNSETVKFCDLLKEVYSELGFNEISVKFSDRPDTRSGNDEVWDRAERALLEAVKEAGLSYELNPGEGAFYGPKLEFILKDAIGRNWQCGTLQVDFILPERLGAFYIGTDGHKHHPVMLHRAILGTFERFIGILIENYAGKFPVWLAPTQLAILTITNESDGYATEISNVLKEQGVRIKTDLTNEKISYKIRLHSSSKVPILWIIGKNEVTNKTVSVRNLGSEKQESFSLENATELLLKIINLN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNA_SALHS
Sequence: MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRLAAGLGIPVYAPDNVNHPIWIDRIAELAPDIIFSFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALTLHHKLCQAARQLLNSILPTMKCGDIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKFTIWSSRICPDAQGALPGSVISVSPLRVACADGALEIITGQAGDGITVQGSQLAQTLGLVAGARLNRPPATSGKRRIRVLILGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLRFTLFRPFNWMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNDGDRCDGKIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKGYQDVAHRKPSIDNARRCLGWEPSIAMRDTVEETLDFFLRSVDVAERAS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: NDK_SALPK
Sequence: MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLESENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSLESAQREIAFFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_HERAR
Sequence: MKRVFNFSPGPAAIPQEVIQQAADEMANWRGCGLSVMEMSHRGREFTEILATTKDDLRSLMSIPDNYKILLMQGGAIAENAIVPMNLVGMKPQPATIDFVNTGHWSIKSIEEARKYANVNVAASSEDQNFTYVPARDTWKLTPDAAYVHVCTNETIGGVEFDFTPDVGNVPLVADMSSNILSREIDVSRYAVIYAGAQKNIGPAGLTIVIVRDDMLGHALPICPSAFDWKLVAEHDSMFNTPPTYPIYIAGLTFQWMKRQGGVAAMEKVNIAKAKLLYDYLDSTDFYVNNVPAANRSRMNVPFFLRDASLNTKFLTEAGQNDLVQLKGHSSVGGMRASIYNAMPIEGVQALVDFMKAFEKKYG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.