PharMolix/UniProtQA huggingface dataset:
Protein: TMP_BPT1
Sequence: MVDKVAGLSLDVDVSTVQRAVKSLKEFSKANDQAADSMGSLINESEVAKQKAKEHAEQLRRQRKEYEAVEKAIDPTVSKMERLKIASQQLDKLWQQGVVPDETFFRLGEMLDLQNAKLARSRAMLTEEGQAALQEAKAKEQAAVRSKAFMDALNGQVNAIGKTHAELMELKAAELGLSKEAAPLIAKLKDQGRAMNAAGISAGEYRQAMRMLPAQITDVVTSLASGMPVWMVAIQQGGQIKDSFGGIGNTFKVLLSYINPVTAGVGVLVGSLGILAKAGYDSYKSITDIQNALIETGGYAGVTAEELDSVSKKIAQTSNSTIGSIREIVTELASSGKYTREQIQNITKATAEWSASTGKSASQIISEFEKIASDPVKGLKKLNEQYNFLEKGQLTYIDTLSRTKGETEAVSEATKLFADVMEKRMKSIADNATPLEKMWSDIKQWASDAWGWVGDHTLGALNLIIDVVQGTVIQVKMILAKGDEYISNFIASAIKATQSLPGMSDFGADVLKEQENIVKSSRDNYDQLASDLDAINARVEKGEMGYIEAMRQRRTLEKQYSEETKEAIRKEAEEIEKRNRERNKQSKIVRSPTEQFDKELISLRAQLKVLQEHKEIGQKLSAQRKALFTTEATIAVLREASSKRQLSAEEKALLASQERVIELAKQKAEIGDQIVKQQQLNDLTDKSLKFVNEMTAATEQLNASRGLSTRDMERQAELAKITTDYINSGGSEGDEKLQNMIKAQNDYYAAEDAKRADWLAGAESAFADYGDAAMDMYGNVNEIASSALNGMSDMMVQFLTTGKANFEDFAKNIIGMIIKMIAQMVIFNTISGMMGGKTWSFAGGASSGASAASQATPTPAASVFRSVSSGGAAVSLAAAAGSVATSGFNASNSAPKVVNHSGGGTVVDVSGMEVKVDNGSDPRGISQGVEMMFKKMIRESCSQGGEVYNYIQEKTGG
What is the function of this protein?
Serves as a ruler that controls the length of tail by stopping the tail tube polymerization and is probably released from the tail shaft during infection to facilitate DNA translocation into the host cell.  Assembles into a multimeric linear form probably arranged as a coil of alpha-helices and stabilized by the covering tail assembly proteins.  Its C-terminus fixes the tail tip complex, thereby forming the tail assembly initiator complex.  Tail tube proteins polymerize around the tape measure protein, displacing the tail assembly proteins.  When the tail reaches the length specified by the tape measure protein, it stops and becomes capped by the tail terminator protein.
What are the official names of this protein?
Tape measure protein, TMP, Gene product 38, gp38.
What is the protein family that this protein belongs to?
Belongs to the Lambdavirus tape measure protein family.
What are the subcellular locations of this protein?
Virion.
Protein: M11L_MYXVL
Sequence: MMSRLKTAVYDYLNDVDITECTEMDLLCQLSNCCDFINETYAKNYDTLYDIMERDILSYNIVNIKNTLTFALRDASPSVKLATLTLLASVIKKLNKIQHTDAAMFSEVIDGIVAEEQQVIGFIQKKCKYNTTYYNVRSGGCKISVYLTAAVVGFVAYGILKWYRGT
What is the function of this protein?
Plays a role in the inhibition of mitochondria-mediated apoptosis by blocking the activation of mitochondria-tranlocalized BAX thereby maintaining pro-apoptotic BAX in an inactive connformation.  Inhibits also apoptosis in a BAX-independent manner by interacting with and inhibiting host BAK1 (PubMed:15194786).
What are the official names of this protein?
Apoptosis regulator M11L.
What are the subcellular locations of this protein?
Host mitochondrion. Host membrane; Single-pass membrane protein.
Protein: RIMO_PROM4
Sequence: MHTSVFKEPKNNDAVLSNHCNASVAFLHLGCEKNLVDTEHMMGLLASEGYGVSSNTDDAEVVVVNTCSFIEQAREESVRALVGLADQGKEIIIAGCLAQHFKSELLESIPEAKAIVGTGDYQNIIEVLQRVRQGERVNQVSENPKFVGDENLPRYRTTGRFVSYLKVAEGCNYRCAFCIIPTLRGNQRSRSVQSIVNEANQLAKEGIQELILISQITTNYGMDLYGRPYLADLLRALSHVDIPWIRIHYAYPTGLTPEVVLAYKEVPNVLPYFDLPLQHSHPDVLRAMNRPWQSDVSSALLNRIKEQLPEAVMRTTLIVGFPGETKAQFDHLCAFVENQKFDHVGVFAFSREEGTEAAKLPNQVPFEIAQARKDKLVAIQQPISAAKNQALIGQTVDVLIEREDLATGELIGRSARFAPEVDGEVRLRPSQVLFNDLHGKIVPALITGSELYDLTGEINHLN
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_BURPS
Sequence: MENRELTYITNSIAEAQRVMAAMLADERLLATVRKVADACIASIAQGGKVLLAGNGGSAADAQHIAGEFVSRFAFDRPGLPAVALTTDTSILTAIGNDYGYEKLFSRQVQALGNEGDVLIGYSTSGKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELCDLLLEVPSADTPKIQEGHLVLGHIVCGLVEHSIFGKQ
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNHI2_BOVIN
Sequence: MEPAGPCGFCPTGEAQPARYTCPRCNVPYCSLRCYRAHGSCAEEFYRDQVLGELRGRSASPSRLATALRRLRQQRETEDEPGDAGLRPGPAPGGLSGLWERLAPAEKVAFERLLSRGEAGRLLPPWRPWWWGRGAGPRLLEELGDAPSGDAEELEPSPARMPPEPVRDEPAAVEQVLGDLPGACPPAVPTRIPALASLSRGRTSPLVRFQLPNVLFAYAHTLALYHGGDEALLSDFCATLLGVSGALGAQQVFASAEEALQAAAHVLEAGEHPPGPLGTRGAMREAARILLGEGPANQKSYTLAALGDLAQTLGRARKQAVAPEERDRLYRARKKCQFLLSWTNENEDALTPLALDCATAHRAHTVAAEDVAALTGELEQLWGGPLPPARRTLIEELPG
What is the function of this protein?
May act as a bridging factor mediating the interaction between the R2TP/Prefoldin-like (R2TP/PFDL) complex and U5 small nuclear ribonucleoprotein (U5 snRNP) (By similarity).  Required for the interaction of R2TP complex subunit RPAP3 and prefoldin-like subunit URI1 with U5 snRNP proteins EFTUD2 and PRPF8 (By similarity).  May play a role in regulating the composition of the U5 snRNP complex (By similarity).
What are the official names of this protein?
Zinc finger HIT domain-containing protein 2.
Protein: BIOB_CLOBH
Sequence: MSNIIKYKKKILNGDLLTKEEVEELLEEDITDLAATANEIRESLCGNKFDLCTIINGKSGRCQENCKYCAQSAHFDTDIIEYNILNSDRIINSAISNYNKGVHRFSVVTSGRALNNNEVDTLCKTYSKLKETCSIRLCASHGLLKYEDLKRLKDSGVTRYHNNLETSRKFFTKICTTHKYDDKIETIKNAKKAGIEICSGGIIGLGETMEDRIDMAFTLRELSVESVPVNILNPIKGTPLENQEILSYEEIIKTLALFRFILPTVQIRLAGGRTIISDKGKKALESGVNGAISGDMLTTLGIETSEDIKMIKNLGFEV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: Y2187_ARCFU
Sequence: MSYRESRQRLERLTESPSHLTIWRRMQELSYESKFEYESFVSADGTKLHAKRSKKLDVKVIAGKSVIVGINESHREMRGEYDVKATVVGDADRDLSCF
What are the official names of this protein?
Uncharacterized protein AF_2187.
Protein: STT7_ARATH
Sequence: MATISPGGAYIGTPSPFLGKKLKPFSLTSPILSFKPTVKLNSSCRAQLIDTVHNLFIGVGVGLPCTVMECGDMIYRSTLPKSNGLTITAPGVALALTALSYLWATPGVAPGFFDMFVLAFVERLFRPTFRKDDFVVGKKLGEGSFGVVYKVSLSKKRSNEEGEYVLKKATEYGAVEIWMNERVRRACGNSCADFVYGFLDKSSKKGPEYWLLWKYEGESTLAGLMQSKEFPYNVETIILGKVQDLPKGLERENKIIQTIMRQLLFALDGLHSTGIIHRDVKPQNIIFSEGSRSFKIIDLGAAADLRVGINYIPKEFLLDPRYAAPEQYIMSTQTPSAPSAPVAAALSPVLWQMNLPDRFDIYSIGLIFLQMAFPSLRSDSNLIQFNRQLKRCDYDLTAWRKLVEPRASADLRRGFELVDLDGGIGWELLTSMVRYKARQRISAKAALAHPYFDRQGLLALSVMQNLRMQYFRATQQDYSEAANWVIQLMAKNGTEKDGGFTETQLQELREKEPRKKANAQRNALASALRLQRKLVKTVTETIDEISDGRKTVWWNRWIPREE
What is the function of this protein?
Serine/threonine protein kinase required for state transition by phosphorylating light-harvesting complex II outer antennae (LCHII).  State transition plays a central role in response to environmental changes and allows to adjust to changing light conditions via the redistribution of light excitation energy between photosystem II (PSII) and photosystem I (PSI).  Phosphorylates the minor light harvesting protein LHCB4. 2/CP29 and is involved in the light-dependent phosphorylation of TSP9.  Acts as a key component of the long-term response (LTR) signaling pathway.  Mediates phosphorylation-dependent PTAC16 subcellular localization to regulate plastid gene expression (PubMed:22616989).
What are the official names of this protein?
Serine/threonine-protein kinase STN7, chloroplastic, Protein STATE TRANSITION 7, Stt7 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane.
Protein: UBP46_DANRE
Sequence: MTVRNIASICNMGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKVQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTVADILQEERKQEKQNGRLKNNGTAIATDTEPEQNKIDPTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEYKYYCEMCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSGDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE
What is the function of this protein?
Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action (By similarity).  Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP12/USP46 subfamily.
Protein: RL28_TOLAT
Sequence: MSRVCQVTGKRPTVGNNRSHAKNATRRRFLPNLQSHRFWVEGEKRFVTLRLTPKGMRIIDKLGIEAVLADIRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CDON_HUMAN
Sequence: MHPDLGPLCTLLYVTLTILCSSVSSDLAPYFTSEPLSAVQKLGGPVVLHCSAQPVTTRISWLHNGKTLDGNLEHVKIHQGTLTILSLNSSLLGYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTENYLILPSGNLQILNVSLEDKGSYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNVLEHASISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLMVVPFETNTKAETVTLPDAAQNDDRSKRDGSETGLLSSFPVKVHPSAVESAPEKNASGISVPDAPIILSPPQTHTPDTYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPGSENELHLAELEPSSLYEVLMVARSAAGEGQPAMLTFRTSKEKTASSKNTQASSPPVGIPKYPVVSEAANNNFGVVLTDSSRHSGVPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGASEYPVKDLSTPPNSLGSGGNVGPATSPARSSDMLYLIVGCVLGVMVLILMVFIAMCLWKNRQQNTIQKYDPPGYLYQGSDMNGQMVDYTTLSGASQINGNVHGGFLTNGGLSSGYSHLHHKVPNAVNGIVNGSLNGGLYSGHSNSLTRTHVDFEHPHHLVNGGGMYTAVPQIDPLECVNCRNCRNNNRCFTKTNSTFSSSPPPVVPVVAPYPQDGLEMKPLSHVKVPVCLTSAVPDCGQLPEESVKDNVEPVPTQRTCCQDIVNDVSSDGSEDPAEFSRGQEGMINLRIPDHLQLAKSCVWEGDSCAHSETEINIVSWNALILPPVPEGCAEKTMWSPPGIPLDSPTEVLQQPRET
What is the function of this protein?
Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells.  Promotes differentiation of myogenic cells (By similarity).
What are the official names of this protein?
Cell adhesion molecule-related/down-regulated by oncogenes.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NDUS8_SOLTU
Sequence: MAAILARKSLSALRSRQLVLAGHTIEGTNGYNRTLLGTRSFATKHSFSTDKDDEEREQLAKELSKDWNSVFERSINTLFLTEMVRGLMLTLKYFFEKKVTINYPFEKGPLSPRFRGEHALRRYATGEERCIACKLCEAICPAQAITIEAEEREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETHEELLYDKEKLLENGDRWETEIAENLRSESLYR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).  May donate electrons to ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial, Complex I-28.5kD, CI-28.5kD, NADH-ubiquinone oxidoreductase 28.5 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
Protein: ACVS_STRCL
Sequence: MMSARYPRTAAEWTTRIQGVSSERCDLEMLLKDEWRNRIAVRDDDPGVRATRQRDIVVDGREYTALKDALRAADGVSAGALALASLHSVMRAYGHGEQTVAAFVDATATAELKTAAVLPVIVDHIEHTRLTCAEAIRELDETLRRKDSYTRADEVLQRGLFDALLVLAEREVALSELPSAPLVMVVRDDAARGRLCWTMAYAGELFEDTTVAGVLEVVREVLGQYAGRPGDRVAEIELASREQRERLQRWNATDGDFPADQRLNDLVEAAVRRSPDREAVVFGTQRLTYREVDARANRFAHWLLGPGLGVRSQQLVGIFLDKSDLGVVATLGIWKAGAAYVPIDPAYPAERVRFAVGDTGLRGIVTNRHHAGRLREILGAEHADVTVVEIESVLDEQAAADTDGLLSVKPELALGVRDLAYLTYTSGTTGVPKGVPKYHDSVVNSITDLSERYDMRRPGTERVALFASYVFEPHLRQTLIALINGQTLVVVPEEVRLDPDRFPAYIEEHGVTYLNATGSVLQHFDLRRRTSLKRLLLVGEELTAAGLRQLRERFSGRIVNEYAFTEAAFVTAVKKFAPGVTERADRSIGRPVRNVKWYVLSQDLKRLPVGAIGELYIGGCGVAPGYLNRDDLTAERFLTNPYASEQDRARGTNARIYRTGDLARMLPSGEVEFMGRSDFQLKLNGVRVEPGEIEAQATEYAGVRKCVVIAREGAGGGSDRHLVGYYLTEPGAGVTEAELLSFLERRLIRIMVPARMVRLESIPVNVNGKVDWRALPEVDLARPDTGGGAVGSTTTGGVRGELREI
What is the function of this protein?
Each of the constituent amino acids of ACV are activated as aminoacyl-adenylates with peptide bonds formed through the participation of amino acid thioester intermediates.
What are the official names of this protein?
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase, Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase, ACV synthetase, ACVS.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: SYP_BRUMB
Sequence: MRLSRYFLPILKENPKEAEIVSHRLMLRSGMIRQQSAGIYSWLPIGLKVLNKVCTIIREEQNRAGANEILMPTIQSADLWRESGRYDAYGKEMLRIQDRQKREMLFGPTNEEMVTDIFRSYVRSYKDLPLNLYHIQWKFRDEVRPRFGVMRSREFLMKDAYSFDLDYEGAKMAYYRMFVSYLRTFARVGLQAIPMRADTGPIGGDLSHEFIILAETGESQVYCDRAYLDLAVPGADTDFRNDAQLTDTVTRWTTPYAATDEMHDEADWAKVKPESQVSARGIEVGHIFHFGTKYSEPMGAKVQGPDGKEHLVSMGSYGIGPSRLVAAAIEASHDDAGIIWPKTIAPFGAGIVNMKPGDEGCDGVSEKLYEALTNAGVDPLLDDKDERPGAKFATIDLIGLPTQVIVGPRGVAAGEVEVKDRKTGERQSLGIEAAINMLTAQA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR83_RAT
Sequence: MAFPEPKPRAPELPRKQLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSVRCWDCRSRKPEPVQTLDEARDGISSVKVSDHEILAGSVDGRVRRYDLRMGQVTSDYVGSPITCTCFSRDGQCTLISSLDSTLRLLDKDTGELLGEYVGHKNQKYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGSLALALPVGSNVVQSLAYHPADPCLLTAMGGSIQYWREETYEAEGGAG
What is the function of this protein?
Molecular scaffold protein for various multimeric protein complexes.  Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists.  At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation (By similarity).  Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3.  May promote degradation of HIF1A.  May act by recruiting signaling complexes to a specific upstream activator.  May also be involved in pre-mRNA splicing.
What are the official names of this protein?
WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MORG1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Partially nuclear.
Protein: ACP_BACCN
Sequence: MADVLERVTKIIVDRLGVEETEVVPAASFKEDLGADSLDVVELVMQLEDEFEMEISDEDAEKIATVGDAVTYIESHL
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_CHLL2
Sequence: MAEQGSIRVSRKDDNVVVIEKDLATEEMLLSMGPQHPSTHGVLKLECMTDGEVVTSAEPYLGYLHRCFEKHCEVVDYPGIVPYTDRMDYLAGMNNEWAYCIAVEKLLDIEIPRRVEFIRVMVSELNRIASHLVAIGTYGIDLGAFTPFLFCFRDREHILNLLEWASGARMLYNYIWIGGVAFDIPADFNKRVKEFVDYFRPKVVELYKLLTENEIFVKRTKGIGIMPADVAINYAWSGPMLRGSGVQWDLRRNDPYSVYPELDFNIPVPDGKFSDIGDCLSRHLVRALEMEESLNIIEQCISKMPGSDGFNPRSAVPKRVRPKAGEVYARAENPRGELGFYIQSDGKSTKPLRCKARSSCFVNLSAMKDLSKGQLIPDLVAIIGSIDIVLGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LPOB_CITK8
Sequence: MMKMNRYALVAALAIFLSGCVGQREPAPVDEVKPAPEQPAEPQQPVPVVPSVPTIPQQPGPIEHEDQTAQPAPRVRHYDWNSAMQPMVGKMLQADGVTAGNVLLVDSVNNRTNGSLNAGEATETLRNALANNGKFTLVSAQQLAMAKQQLGLSPQDSLGTRSKAIGIARNVGAQYVLYSSAAGNVNAPSLQMQLMLVQTGEIIWSGKGAVQQQ
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).
What are the official names of this protein?
Penicillin-binding protein activator LpoB, PBP activator LpoB.
What is the protein family that this protein belongs to?
Belongs to the LpoB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: RL23_STRS2
Sequence: MNLYDVIKKPVITESSMGQLEAGKYVFEVDTRAHKLLIKQAVEAAFEGVKVANVNTINVKPKTKRVGRYVGRTNKVKKAIITLAADSKAIELFATADAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: 460R_IIV6
Sequence: MEVGCVYIITTQLYEPLDIYKIGCTKDINRRLKTMNASRISFDKFFIVNQIQTFHYFKLEQGLHKLLKKYRLNNEFFQCNVNIIEKAISDYANNNVFMLHDDKIAHVAIEKKLKWFQKNNLFSITDTNLEIFLNESSLINEIKQWLSVFDKHNLYKFLHPSHFYNIVSYLKTVCIQNDDEEEFLINEMNMLSINTKDDNSKDDNNDSEDLSKQIDNLKLD
What are the official names of this protein?
Uncharacterized protein 460R.
Protein: TPC1_CANGA
Sequence: MNKKDHLRKDEEVSTTNSLVAGSLSGLFARTCIAPLDTVKIKLQVTPHNKNANVLINILKREGIRGFWKGNVPGSIMYIIYGGAQFGSYTYIGSFLRGGLDLNISPQLYSCLVGSLAGMTSSLASYPFDVLRTRFAANSQGQLIKLRDEIMAIWSHEGLMGFFSGCGSSMINIGLNTAIMFGVYESIKIFTEERSKLSDRRDPFTLLNELAGPISGFTSKLATFPLDTVRRRIQIRNSPNEERHDREFTKDIYKSYKNRRFLGVGISMVQQEGPLSLYRGVTMSLIKSVPSTAISLWSYELFMNKLG
What is the function of this protein?
Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
What are the official names of this protein?
Mitochondrial thiamine pyrophosphate carrier 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TM53B_XENLA
Sequence: MGDPELDYTIEFPEPSLQGCPWDPEREPVVILLGWGGCKDQYLAKYSAIYHNQGCTVIKYTAAWNAVFISESLGFSSLREDAKKLLELLFDYEIEKSPILFHVFSNGGFMLYRYIVELLHSHCRLNKLHVVGTIFDSAPGNRNVIGSVRALDTILRTSTNNAIRFLALAAFAIMVIILRIVLYPVTKFLHENHYDAMKKDSSRWPQLYLYSRADPIISYIDVESMIAARRRCCLPTEALDFGKSEHVSHFRRFPHRYSEMCTSFLRDCVRKAAVSMLTSEHPVSF
What is the function of this protein?
Ensures normal bone formation, through the negative regulation of bone morphogenetic protein (BMP) signaling in osteoblast lineage cells by blocking cytoplasm-nucleus translocation of phosphorylated SMAD proteins.
What are the official names of this protein?
Transmembrane protein 53-B.
What is the protein family that this protein belongs to?
Belongs to the TMEM53 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RLMH_ACTP2
Sequence: MKIQLIAVGQKMPDWVKVGFEEYQRRFPKDMPFELIEIPAGKRGKNADIKRILEQEGKAMLAAAGKGKVVTLDIPGKPWTTEQLASQLEAWKNDGRDVCLLIGGPEGLSPECKAAAEQSWSLSPLTLPHPMVRVIVAESLYRAWSLTTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_DECAR
Sequence: MSITTPRILGIDPGLRVTGFGVIELHGKQLVYVASGCIKSNDKESLPERIKTLFAGISEVIATYQPNQAAVEKVFVNVNPQSTLLLGQARGAAISALVHADLPVAEYTALQTKQAVVGHGKAAKDQVQAMVVRLLNLPGAPTADAADALACAIAHAHGGQGLGAMATAGYRIRGGRLIG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TGT_STACT
Sequence: MKPAVTYEHIKTCKQSGARLGIVHTPHGSFETPMFMPVGTKATVKTMSPEELHDINAKIILGNTYHLWLQPGNELIKRAGGLHQFMNWDGPILTDSGGFQVFSLSNLRKITEEGVYFRHHKNGSKLFLSPEKSMEIQNDLGSDIMMAFDECPPMPAEYKYVKDSIERTTRWAERCLKAHARPEDQALFGIIQGGEYKDLRQQSAEELVKLDFPGYAIGGLSVGEPKPVMYDMVEHTEQFMPKDKPRYLMGVGSPDALIECSIRGMDMFDCVLPTRIARNGTCMTSEGRVVIKNAKYADDLGPLDPNCDCYTCRNYSRAYLRHLIKAEETFGIRLTTYHNLYFLLKLMEDIRQAIREDRLLDFKEEFFEQYGLNVENPKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.