PharMolix/UniProtQA huggingface dataset:
Protein: CM3A_CONTS
Sequence: MMSKLGVLLTICLLLFPLTAVPLDGDQPADQPAERKQNEQHPLFDQKRGCCRWPCPSRCGMARCCSS
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav).  This toxin specifically inhibits mammalian Nav1. 8/SCN10A sodium currents (IC(50)=2. 11 uM) without inducing a shift in the current-voltage relationship of this channel (PubMed:32758497).  In vivo, shows potent analgesic activity in a mice hotplate analgesic assay (PubMed:28219625).  In addition, this toxin has better analgesic effects than Ziconotide, an analgesic drug (PubMed:28219625).
What are the official names of this protein?
Mu-conotoxin TsIIIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LUR1L_RAT
Sequence: MEDGPLPDLRDIELKLGRKVPESLARSLRGEEPAPREGAADPSGVGGSCSSSSSCSSFAPSVSSSSSSSPASGSPRRSHPSALERLETKLHILRQEMVNLRATDVRLMRQLLLINESIESIKWMIEEKATVTSRGSSLSGSLCSLLESQSTSLRGSYNSLHDGSDGLDGISVGSYLDTLADDVPGHQTPSDLDQFSDSSIIEDSQALHKHPKLDSEYYCFG
What are the official names of this protein?
Leucine rich adaptor protein 1-like.
Protein: INSR_DROME
Sequence: MFNMPRGVTKSKSKRGKIKMENDMAAAATTTACTLGHICVLCRQEMLLDTCCCRQAVEAVDSPASSEEAYSSSNSSSCQASSEISAEEVWFLSHDDIVLCRRPKFDEVETTGKKRDVKCSGHQCSNECDDGSTKNNRQQRENFNIFSNCHNILRTLQSLLLLMFNCGIFNKRRRRQHQQQHHHHYQHHHQQHHQQHHQRQQANVSYTKFLLLLQTLAAATTRLSLSPKNYKQQQQLQHNQQLPRATPQQKQQEKDRHKCFHYKHNYSYSPGISLLLFILLANTLAIQAVVLPAHQQHLLHNDIADGLDKTALSVSGTQSRWTRSESNPTMRLSQNVKPCKSMDIRNMVSHFNQLENCTVIEGFLLIDLINDASPLNRSFPKLTEVTDYIIIYRVTGLHSLSKIFPNLSVIRGNKLFDGYALVVYSNFDLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEILAENETQLVVLTENGKEKECRLSKCPGEIRIEEGHDTTAIEGELNASCQLHNNRRLCWNSKLCQTKCPEKCRNNCIDEHTCCSQDCLGGCVIDKNGNESCISCRNVSFNNICMDSCPKGYYQFDSRCVTANECITLTKFETNSVYSGIPYNGQCITHCPTGYQKSENKRMCEPCPGGKCDKECSSGLIDSLERAREFHGCTIITGTEPLTISIKRESGAHVMDELKYGLAAVHKIQSSLMVHLTYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGPNQTVFIRKGGVFFHFNPKLCVSTINQLLPMLASKPKFFEKSDVGADSNGNRGSCGTAVLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYHMIDPYGNSTKSSDDPCDDRWKVSSPEKSGVMVLSNLIPYTNYSYYVRTMAISSELTNAESDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYGVLTRYFIKAKLINRPTRNNNRDYCTEPLVKAMENDLPATTPTKKISDPLAGDCKCVEGSKKTSSQEYDDRKVQAGMEFENALQNFIFVPNIRKSKNGSSDKSDGAEGAALDSNAIPNGGATNPSRRRRDVALEPELDDVEGSVLLRHVRSITDDTDAFFEKDDENTYKDEEDLSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAGYLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPSYAKVFFWLLGIGLAFLIVSLFGYVCYLHKRKVPSNDLHMNTEVNPFYASMQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFAAVPLDQDLQDREQQEDATTPLRMGDYQQNSSLDQPPESPIAMVDDQGSHLPFSLPSGFIASSTPDGQTVMATAFQNIPAAQGDISATYVVPDADALDGDRGYEIYDPSPKCAELPTSRSGSTGGGKLSGEQHLLPRKGRQPTIMSSSMPDDVIGGSSLQPSTASAGSSNASSHTGRPSLKKTVADSVRNKANFINRHLFNHKRTGSNASHKSNASNAPSTSSNTNLTSHPVAMGNLGTIESGGSGSAGSYTGTPRFYTPSATPGGGSGMAISDNPNYRLLDESIASEQATILTTSSPNPNYEMMHPPTSLVSTNPNYMPMNETPVQMAGVTISHNPNYQPMQAPLNARQSQSSSDEDNEQEEDDEDEDDDVDDEHVEHIKMERMPLSRPRQRALPSKTQPPRSRSVSQTRKSPTNPNSGIGATGAGNRSNLLKENWLRPASTPRPPPPNGFIGREA
What is the function of this protein?
Has a ligand-stimulated tyrosine-protein kinase activity.  Required for cell survival.  Regulates body size and organ size by altering cell number and cell size in a cell-autonomous manner.  Involved in the development of the embryonic nervous system, and is necessary for axon guidance and targeting in the visual system.  Also plays a role in life-span determination.
What are the official names of this protein?
Insulin-like receptor, dIR, dInr, dIRH.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LPXC_CAMJR
Sequence: MKQLTLAKTVKGVGIGLHKGEPIEITLEPLEANSGIVFFRSDLNASYKASPENVINTQMATVLGDERGFISTIEHLMSAINAYGIDNVRIVLNANEAPVMDGSSISFCMMLDEAGVKELDVPKKIMVIKKPIEVRDGNKFVRLTPTKEPRINYTIKFDNAVIGEQSYNFEFSKKNYIENIARARTFGFLKDVQALRSMNLALGGSLENTIVVDENRILNPEGLRFKDEFVRHKILDAIGDLTLLGYRVFGDYTSYAGSHHLNHLLTKEVLKDKDAYEIVSLEKTTQKAYEKVFA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: POTD2_HAEIN
Sequence: MKKFFAHSLKNLFLSTTALFAASAFANNKLYVYNWTDYVPSDLVAQFSKETGIEVIYSTFESNEEMYAKLKLTQNTGSGYDLVFPSSYYVNKMIKEKMLQPIDQSKLTNIHQIPKHLLNKEFDPENKYSLPYVYGLTGIEVNADEIDPKTITSWADLWKPEFKGKVLMTSDAREVFHVALLLDGKSPNTTNEEDIKTAYERLEKLLPNVATFNSDSPEVPYVQGEVAIGMIWNGSAYLAQKENQSLQFVYPKEGAIFWMDNYAIPTTAKNVEGAHKFIDFLLRPENAKIVIERMGFSMPNNGAKTLLSAEVANDPKLFPPAEEVEKGIMQGDVGEAVDIYEKYWGKLKTN
What is the function of this protein?
Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.  Polyamine binding protein (By similarity).
What are the official names of this protein?
Spermidine/putrescine-binding periplasmic protein 2, SPBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein PotD/PotF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RAP1_PLRV1
Sequence: MTPMRITVWRERLQQMRPQRKLLKQTQQRRLLHQLQQRKLL
What is the function of this protein?
Involved in viral RNA replication.
What are the official names of this protein?
Replication-associated protein, Rap1.
Protein: MNME_PSYIN
Sequence: MIKAIDTIVAQATAPGRGGVGIIRISGPDVEAVAKVILGKVPKLRFAEYLSFSDQHNEVLDQGIALFFKAPNSFTGEDVLELQGHGGPVVMDMLIKAILSIKNLRGANPGEFSERAFMNDKLDLAQAEGIADLIEATSEQAAKSALHSLQGEFSEKIEQLVESLIYLRIYVEASIDFPEEEVDFLSDGKISKGLYQIIDNLEAVKKQAKQGAILRDGMKVVIAGRPNAGKSSLLNSLVGVERAIVTDIAGTTRDVMREHIHIDGMPLHIIDTAGLREGADEIEKIGIERAWQEITTADRILFMLDATTTSAEDPRQIWPDFIDKLPKSVGLTVVRNKADLTGEAFSMTENHDHPVYRISAKTGQGVDLLKEHLKDIMGYQGHTTSGFMARRRHLEAIDNAQRHLLEGKVQLEEYKAGELLAEELRLTQQYLSEITGAFSSDDLLGKIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG4C_MOUSE
Sequence: MEASGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDESKMLPARSGCAIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEASALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALHIENADSDSWTSNTVKKFTASFEASLSGDRELRTPAVSLKETSGKCPDDHAVRNEAYHRKIISWFGDSPVAVFGLHRLIEFGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGLTIYVAQDCTVYNSDVIDKQTDSVTAGDARDKAVIILVPVRLGGERTNTDYLEFVKGVLSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFERASEEITKMLKISSKEKYPLFTFVNGHSKDFDFTSTAASEEDLFSEDERKNFKRFSTEEFVLL
What is the function of this protein?
Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.  The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine (By similarity).  Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy (By similarity).  In addition to the protease activity, also mediates delipidation of ATG8 family proteins.  Catalyzes delipidation of PE-conjugated forms of ATG8 proteins during macroautophagy.  Compared to ATG4B, the major protein for proteolytic activation of ATG8 proteins, shows weaker ability to cleave the C-terminal amino acid of ATG8 proteins, while it displays stronger delipidation activity.  In contrast to other members of the family, weakly or not involved in phagophore growth during mitophagy (By similarity).
What are the official names of this protein?
Cysteine protease ATG4C, AUT-like 3 cysteine endopeptidase, Autophagy-related cysteine endopeptidase 3, Autophagin-3, Autophagy-related protein 4 homolog C.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_SERMA
Sequence: DPAVDIFDREARFIEQVMEPIRQHFPELKIVFEHITTKEAAQYVQAGNRFLGATITPQHLMFNRNHMLVGGIRPHLFCLPILKRNVHQEALRQAVASGSDRFFLGTDSAPHLKHRKESSCGCAGCFNAPNAIPAYAAVFEQLGALEHFEAFCSLNGPRFYGLPLNEDFIELQRVPTTQPEEIALGNESVIPFLAGETLNWSLKD
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: ISPG_BACFR
Sequence: MDLFNYSRRETSEVNIGAVPLGGPNPIRIQSMTNTPTQDTEACVAQAKRIVDAGGEYVRLTTQGVKEAENLMNINIGLRSTGYMVPLVADVHFSPKVADVAAQYAEKVRINPGNYVDPGRTFKQLEYTDEEYAAELQKIRDRFVPFLNICKENHTAVRIGVNHGSLSDRIMSRYGDTPEGMVESCMEFLRICVDEKFTDVVISIKASNTVVMVKTVRLLVSVMEQEGMSFPLHLGVTEAGDGEDGRIKSALGIGALLADGLGDTIRVSLSEEPEAEIPVARKLVDYITSRRNHPYIPGMEAPDFNYLSPVRRKTRPVRNIGGDHLPVVLADRMDGRMETHPQFTPDYIYAGRALPEQTEPGVQYILDADVWKGEPDTWPAFNYAQLELMETCAAELKFLFTPYMALTREVVACLKQHPEAVVVSQSNHPNRVGEHRALAHQLTVEGLQNPVIFFQHYAEDTAEDLQVKAGADMGALIFDGLCDGIYLFNQGKLSHAVIDATAFGILQAGRIRTSKTEYISCPGCGRTLFNLQSTIARVKEATSHLKGLKIGIMGCIVNGPGEMADADYGYVGAGRGKISLYKQKECIEKNIPEEEAVEKLIELIKANGDYEEKTSSLSSPKEKEDK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: F217A_MOUSE
Sequence: MGRKSNESCSSSLHVSSISQENHSQWNLDAEELFDEKETFSSENDGAAGGKTNKSHLENPAEQLILQLTVSEHAHSRSQQNSSQGVFQLWSSPVNKGSTVDKRNSSVEENVTDESDLSENEKMNDSLLSYFKKMDLNLKPETIEHVERPFPEEAGQVPVYADFLPAPFNTLDLHRFAFSKCESWKAAVEPPESSIERLILRLLELERLQHMTIQRERPRLQSTFYSSMFSMAERPSSSKAIATKAKAPKIPETSTLQTSGVDKNRDKRKNNSGSGKPEQNVSKWSLSSAGKSKSNSRALLKCSSTSKQCAVAHDDLKNSKNSSLNPCQEPPLKPTTTTQATQPMARVVSRCLPPRSPMPVSPIPLSFPENPREEGKVPRTKKKCHRKSILLNRAFYIQKRNCLSPSLIARGKCSPTDQK
What are the official names of this protein?
Protein FAM217A.
What is the protein family that this protein belongs to?
Belongs to the FAM217 family.
Protein: RBFA_ERWT9
Sequence: MAKEFGRPQRVSQELQKEIAIILQREIKDPRLGMMVTVSGVDVSRDLAYAKVFVTFLNDKDEAAIKGGLRALGDASGYIRTLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTNVVRNDEERRGPAEENPEEGKAE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_STRP6
Sequence: MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGKTLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSPAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDEEDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDDQIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAPQNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: CBPM_COXBN
Sequence: MTKQIIKGIIIERSSPLKIDELSQAVHLRREIIIEMVEHRLIEPEGSSPTSWKFDNVCLKRAKIAASFYRDLEINMPGIAIALDLLDKIEHLEQRLRTLERFENQE
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: HFLD_EDWI9
Sequence: MAKNYYDITLALAGICQSARLVQQLAHDGQCDNVALRTSLSSILQTDPPNTLAVFGDHERVLKPGLETLLNVLNANRQGPGAELTRYCLSLMLLERKLFGHPQALRTLSERIGELDRQLAHFDLESDTIVSALAAIYVDVISPLGPRIQVTGSPAVLQNALVQARVRAALLAGIRAGILWQQVGGSRLQLMFSRNRLFQMAQNLLTHS
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DPPF_LACLM
Sequence: MTEPKKVVEIKNLDLTFNKGKKGANKAINNVSLDIYEGETFGLVGESGSGKTTIGRAILKLYDNFITGGEILFEGKDVRNLKGSELREYRSEAQMIFQDPQASLNGRMRVKDIVAEGLDANGLVKTKAERDARVLELLRLVGLNDDHLTRYPHEFSGGQRQRIGIARALAVKPKFVVADEPISALDVSIQAQVVNLMRDIQAKENLTYLFIAHDLSMVKYISDRIGVMHWGKILEVGTSEQVYNHPIHPYTKSLLSSIPSPDPISERQRTPIVYDPTAELDGQEREMREITPGHFVFSTEAEAEVYKKNATL
What is the function of this protein?
Part of the ABC transporter DppABCDF involved in dipeptide transport (PubMed:11409543).  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Dipeptide transport ATP-binding protein DppF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRUB_COXBR
Sequence: MTATNHPKLFKRPVDGVLLLDKPGGMTSNEALQRVKRLFHAKKAGHTGSLDPLATGLLPICLGEATKFSQFLLEADKSYSVKGRLGVRTASGDSESPILTECPIPKLTKRALEKTLFAFRGVIDQTPSMYSALKHKGQPLYKLARQGIEVERKTRQVTIYELTLLDWDNESIELYVHCSKGTYIRTLLDDVGEALGCGAHVVALRRLRVAHYHEDQMIKLAHLEREYDKANYTGLDRYLLPLETMVSHFPAIKLSSSTAFYLQQGQAVMVPNAPTHGFVRLRDQNDQFIGIGEILSDARIAPRRLIQKR
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RS3_CAMFF
Sequence: MGQKVNPIGLRLGINRNWESRWFPSKATLPENIGEDYKIRKFLKTKLYYAGVSQILVERTAKKLRVTVVAARPGIIIGKKGGEIENLRSEVTKLVNKDIAINIKEERKAGSSAQLAAENVAMQLERRVAFRRAMKKVIQGAQKAGAKGIKVSVAGRLGGAEMARTEWYLEGRVPLHTLRARIDYGFAEAHTTYGNIGVKVWIFKGEVLQKGIQADKNEDTSPKKPRRARRGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: CH60_CHLPB
Sequence: MSAKDILFDASARAKLKVGVDKLADAVKVTLGPAGRNVLIDKKFGAPTSTKDGVTVAKEIELEDSFENMGAQMVREVSSKTSDVAGDGTTTATVLAQAIYREGLKNVAAGARPIDLKRGIDKAVKEVIGELRTISNDISGKIEIAQVGTISANNDPEIGQLIADAMEKVGKDGVITVEEAKGMDTELKVVEGMQFDRGYLSPYFVTNSEKMDAELEDPYILIHDKKISNMKDLLPILEKTAQSGRPLMIISEDIEGEALATLVVNKLRGTLKVCAVKAPGFGDRRKAMLEDIAILTGGTVISEEKGYKLENATISYLGQAATVTVDKDNTTIVEGKGQADDIKARINEIKNQIDASTSDYDTEKLQERLAKLSGGVAVINIGASTEVEMKEKKARVEDALHATRAAVQEGIVAGGGVALIRAAKGLDNVQPENEDQKTGVEIVRRALEEPLRQIVANTGTTDGAVVVERVKQGEGDFGFNARTEEYEKMTEAGVVDPTKVTRTALENAASVAGILLTTEAAITDIKEEGGDMPAMPPGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_SODGM
Sequence: MSSKLVLVLNCGSSSLKFAIIDAANGEEHISGLAECFNLPEARIKWKMDGAKQEAALGAGSAHSEALHFIVNTILAQKPELSAQLTAIGHRIVHGGERFIQSAIIDDDVVKGIENSIPFAPLHNPAHLIGIREALKEFPQLTQKNVAVFDTAFHQTMPEESYLYALPYSLYQDHAIRRYGAHGTSHYYVSREAAKLLDKPVDQLNVITCHLGNGGSVSAIRNGQCVDTSMGLTPLEGLVMGTRSGDIDPAIVFHLHDALGMSVAQINTLLTKESGLLGLTGVTSDCRYVEDNYREKADSRRAMDVYCHRLAKYIGSYSALMEGRLDAVIFTGGIGENAAMVRELSLKKLALLGFEVDHERNLAARFGHGGVITTDTSRPAIVIPTNEELVIAQDAARLTA
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT5_SCHPO
Sequence: MDTNSPKSIDKDANSTEVDAAEQDAASVKINSTRASPNGSDLLNDDSEAAKITTNEKQSSPVDSHNESPNDTTINKGEDGNENEVDNVNNNDKKEDEDNVEENEEEADANEEEEEDEEDDEEDEEDEDESGGGRRKRARHDRRNQFLDIEAEVDEDEEELEDEEDEIGREDGFIEEEVGADYVGDDRRHRELDRQRQELQSVDAERLAEEYREKYGRSQTVVGDTSNVPQRLLLPSVNDPNIWAVRCKIGKEKDIVFTIMRKAMDLQYTSSPLEIISAFQRDSLVGYIYVEARKQSHVLDALNGVLNVYTNNMILVPIKEMPDLLKVQKQVVELLPGAYVRIRRGKYAGDLAQVDNLSENGLTARVRIVPRIDYSDGLKRKNSATRPQARLFNESEAFKSNPSKFSKRGPRLFLFNNEEFEDGFLVKDIRISSLITEGVNPTLDEVSKFNPNNEDLDLSSLALSVKGGHAEFQPGDHVEVYVGEQTGVSGVVENVRGSVITMVSSDGLRLDVPSRGLRKRFRHGDYVKVIAGKYKDDTGMVVRISKDEVTFLSDTLMTELTVFSRDLGEASSAQAVNSAYELHDLVQLDVNTVACIFSVDRDTYKVIDQNGGVRTVLASQITMRHSNRRGVATDRNGAEIRIGDKVKEVGGEGKQGTILHIYRAFVFLHNRDIAENNGVFSARSRNVATIAAKGARISADLTKMNPALSNGPALPPVANLKRTIGRDKAIGATVRIRRGPMKGLLGVIKDTTDANARVELHTGNKMVTIPKENLLYTTKTGELISYTEFIERSRGIRPGSISTADGPNVPNWAQGARTPAVANGSRTPAWNTGSRTPAWNSGSKTPAWNSGSRTPAWNSGNKTPAWNAGSRTPAWNSGNKTPAWNVGNKTPAWNSGAKTPAWNAGNKTPSWNNGTKTPAWNANQTPMVANGTNTSWGQTPAYGGFSETNWDTEDNSKPYTAPTPGAWAAPTPGGWDDEEGDSPKYVPPSP
What is the function of this protein?
The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing.  This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
What are the official names of this protein?
Transcription elongation factor spt5, Chromatin elongation factor spt5.
What is the protein family that this protein belongs to?
Belongs to the SPT5 family.
Protein: AB25G_ORYSJ
Sequence: MAASQLLAAAVAAAVFLAALLVPPARCQQQQVANPGPRVRQAARIDAVRDELAAEVQAKYGFCMANVQEDFTQAFSFSNASFVSDCMEETQGQMTGMLCGKAEIEIYVKSLGKKPSTRVSRNCDQNSWALGCQPGWACARQDSSSSGREVPSRAVNCRPCYPGFFCPRGLTCMIPCPLGAYCPLATLNDTTGLCDPYSYQITPGSNTACGTADSWADVITTDDVFCPPGHHCPTTTQKFNCTEGYYCRKGSTEEHKCIWKNTCKENSTKEATALFGGILIVILSVVLLLVYNCSDQFIKIRAKILSKSRRKAATIAQESATARGRWKLAKELVLSHELEMSESDQLAASSNEARHATEGNGKRSKNRKKLAHARTERFRRAYSQIGRERVLQPDNDKITLSGVVALAAENRSRRPMFEVVFKGLTLSIGKKKLLQCVTGKLSPGRVTAIMGPSGAGKTTFLNAVLGKTTGYKKDGLVLINGKSGSMQSYKKIIGFVPQDDIVHGNLTVEENLWFSACCRSSKGMSKSDKIIVLERVIGSLGLQEIRNSLVGTVEKRGISGGQRKRVNVGIEMVMEPSLLILDEPTTGLDSASSQLLLRALRHEALQGVNVCAVIHQPSYTLFNMFDDFVLLARGGLIAYLGPISEVETYFSSLGIKVPERENPPDYYIDILEGITKTKMRGHAAPKHLPLLWMLRNGYEVPEYMQKDLEDINNVHELYTVGSMSREESFGDQSENADSVHQNVREPYSLLDRKTPGVLAQYKYYLGRVTKQRLREATLQAVDYLILCIAGICIGTIAKVKDDTFGVASYGYTIIAVSLLCQLAALRSFSPERLQYWRERESGMSTLAYFLARDTIDHFNTLVKPVAFLSTFYFFNNPRSEFKDNYLVFLALVYCVTGIGYTFAIWFELGLAQLCSALIPVVLVLVGTQPNIPNFIKGLCYPKWALEALIIAGAKKYSGVWLITRCGALLKGGYDINNFVLCIVIVMLMGVLFRFIALLSLLKLK
What are the official names of this protein?
ABC transporter G family member 25, OsABCG25, Putative white-brown complex homolog protein 26, OsWBC26.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CREG2_MOUSE
Sequence: MSLSGRERPAWPGSRLSWLLCCSALLSPAAGYVIVSSVSWAVTNEVDEELDSASTEEALPALLEDSSSIWQQSFPASAHKEDTHLRPRGSARARPAPAARGMFSYRRESGSSEASPGPRVHAGTARSLAHASSWGCLATVSTHEKIQGLPFGSCLAISDGPVHNSTGIPFFYMTAKDPAVADLVKNPTASLVLPESEGEFCRKNIVDPEDPRCARLTLTGRMVTVPPGEVEFAKQAMFSRHPGMRKWPRQYEWFFMKMWVEHIWLQKWYGGVSDIPREEYFKAAPRKA
What are the official names of this protein?
Protein CREG2, Cellular repressor of E1A-stimulated genes 2.
What is the protein family that this protein belongs to?
Belongs to the CREG family.
Protein: LLDD_YERPY
Sequence: MIISASTDYRAAAQRKLPPFLFHYIDGGAYNEQTLRRNTADLADIALRQRVLKNMSELSLETQLFGETQAMPVVLGPVGLSGMYARRGEVQAARAADKKGIPFTLSTLSVCPIEEVAPAIARPMWFQLYVLKDRGFMRNALTRAQAAGVKTLVFTVDMPVPGARYRDAHSGMSGPNAAARRLLQAIAHPQWAWDVGLNGKPHDLGNISAYLGKPTTLEDYMGWIATNFDPSISWKDLEWVREFWQGPMIIKGILDPEDAKDAVKFGADGIVVSNHGGRQLDGVLSTARALPAIADAVKGDITILADSGIRTGLDVVRMIALGADSVLLGRAFVYALATAGEAGVINLLTLIEQEMRVAMTLTGAKRIADINRDSLAVSERG
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL21_ECOLU
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: BEST_PARTR
Sequence: ADVPGNYPLDKDGNTYTCLELGENKDCQKVCKLHGVQYGYCYAFSCWCKEYLDDKDSV
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  In mice, causes intense writhing.
What are the official names of this protein?
Bestoxin.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.