PharMolix/UniProtQA huggingface dataset:
Protein: PLSX_MYCMS
Sequence: MYKIAFDVMGSDLGSLTAIKAASEFIKEHDDLYLVLVGDETEIKQALQQTPIDKTKYEIFPTTQVIDMNGSILDIRRKKDASIIRTLELVRDQKVDGMLTGGNSAAFIGAAHFILGELNNIVRAGFMPTMPNAKNKLTLLLDVGANSENTPEDLVNYAKMANIYYKEVLKNPNASIGLLNIGTEKSKGLELQKQTFKQLEELKNINFIGNVESRDVLTGNVDIIVTDGYSGNICLKACEGAAKVLLTEIKKEITSSFIKKLASLVLKKSFKNVAAKFDYKNHAGAILLGVKGICFKSHGSSDVRSFKATLRMTLDAIKNDIVKKIEKGLIENEY
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: Y3116_VIBC1
Sequence: MSKKDTEHDDDFALFKDAVQGVKKLRQDTIIQQPKKNTKQKEITRSNREASDSEFYFSDEFVPLLNADGPTRYARDDVSTYEVKRLRRGVYVPDVFLDMHGMTQQEAKRELGAMIAYCVKNEIHCACVQHGIGKHILKQKAPLWLAQHPDVMAFHQAPLEFGGDGALLVLLSIPEK
What are the official names of this protein?
UPF0115 protein VIBHAR_03116.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: SECA_RUBXD
Sequence: MNLLTKILRMGEGRKLKALQRTVEEVSAREPEVRGLSDAALRARTDEFKERLQGGETLDDLLPEAFAVVREVARRTLGLRPFDVQVMGGVVLHQGKIAEMKTGEGKTLVATMPVYLNALAGRGVHVVTVNDYLARRDAEWMGPIYEFLGLEVGVIQESMGFEERKKAYAADITYGTNAQFGFDYLRDNIATSPDQLVQRELHYAIVDEVDSILIDEARTPLIISGLPESAADLYYRFAAIVPRLREGEDYEVDEKKRQVAPTEQGVAKVEKALGIPNLYDGVNTNLVNHLIQALRAHTLFRRDREYIVRDGQVFIVDEFTGRVLEGRRYSEGLHQAIEAKEGVEIKEENQTVATITIQNYFRQYEKLAGMTGTAATEADEFMHTYKMEVVSIPTHRPMIRVDRDDLVYRTKKAKYAAVIDDIVERHRKGQPVLVGTVSVEVSEHLSALLKRRGIKHNVLNAKHHEREAEIIAEAGKKGAVTIATNMAGRGTDIKLGGSDESGGGEEWTEEHERLASEIMEKYPTITRDMLEGRSLESLEVVNLGGLYVLGTERHEARRIDNQLRGRSGRQGDPGESRFYLSFEDDLLRLFGGQRMQSLMERIGLEEDEAIEAGMVSNSVRRAQEQVESRNFQMRKRILEYDDVLNKQREVIYAIRREILMGEKVDTMSYVEDVLTDVISRYASEDVYPEEWDLEGLATELNRFYPCQVDFSSLDIESATADQVREMVLEDARERLEERRAEWEERTAELERRGLARADGLDSFEEAERRTLLSVVDSRWREHLYEMEYLREGIGWRGLGQRDPLVEYKREGYDLFVEMERGIREDYVTYIYRIENLKLSETDVERLSYSGGGEEPNQRPKSPRRRSERKIGPNEPCPCGSGKKFKKCHGRVGAPPLPTSQSQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: Y1836_STAS1
Sequence: MNPIVEFCISNLAKGGDYVYNQLENDPGIDVLEYGCLQNCGICSSGLYALVNGDIVEGESPDDLLQKIYAHIEETWIF
What are the official names of this protein?
UPF0349 protein SSP1836.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: Y828_RICPR
Sequence: MKKLLLIATASATILSSSVSFAECIDNEWYLRADAGVAMFNKEQDKATGVKLKSNKAIPIDLGIGYYISENVRADLTLGTTIGGKLKKYGAATNTHFTGTNVSVSHKPTVTRLLINGYVDLTSFDMFDVFVGGGVGPALVKEKISGVSGLASNTKNKTNVSYKLIFGTSAQIADGVKVELAYSWINDGKTKTHNVMYKGASVQTGGMRYQSHNLTVGVRFGI
What is the function of this protein?
Adheres to biotinylated epithelial (Vero cell) proteins.
What are the official names of this protein?
Putative adhesin RP828.
Protein: TIM8A_RAT
Sequence: MESSSSSSGSALAAVDPQLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPGPKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim8 A, Deafness dystonia protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: HIR3_CHAGB
Sequence: MAAFSAINVEPEENIDEEVDTTKDLQVDDALKLFQNALKLHAQGPQSFDQAADAYDALFESEIFKYPESKTDYERFEAGQDGTLATEPVFAQGLPPVGADVDGIGSSLPQALYLSHKNHGQFVIDRIKHKVRKSTKKREPLLKDAGVQKDAQRALDDFCVALDRDPSDAELWRKTARVAAFLKSARINRYSLEAAIELEDDPAVEEVDPPSLAEGFAGEQLKQQLQVLGDDMALTHPIMNPFVHREMPPYLARFMDPMPFLPDPTKRLAVKELRDTEIETARSVLPISIPSWSELGAAIVRFVTKEGLAGQGVLIQLPDTDEQEDVQMEVDMQLQPEEPSSQSGTPDEVVEAEEAVAEPPSEEATVEGLTSAPAPESSPTDEQASKDPNNSISTRKRSQSAAGIPDALEDDAADVKRSKRTRRRDTAVEEVMDSATFLASQLQPLQAADQNLFQTTKNLLENLGVTDQVTLGRIAEVLDSCAADDRTGKIQNQATVDLSHSITHFDEDTGAVLLSKRELPQLSLSAFLEHAKTGSQRAQEASAFDDSRGLKSFVENVNQGWNTIHDIAYKYVKALVKTYTEYKWPDQLRTAVIDVTGRLEGSIYDSFAYELELSPKDVQGETISELAGLAQTLFELHLDVYDHITDPNSTADQEAKLEAKCRVDRWADMAGEVIRLRTLEPDDPIALRFLWASVASTTMAKGTPRDHVLNCWHSLRDFLLGSAATEVNLVNNTTMPEISTAAAEREISKLTTMDFFLGLFQEDNGNPVAVVESLEPVLNPEGVYITIPATLKQADAGGDAPSDKPGKLPIAECASQELTDLWKFLKGSNTELRLLLWSRLGEAYGKIQYTTKQFSCFLRSIETVISDLESDDYLHSTDEPRRNQFMSLLKALDDLIIQSLHLALNDNSSFDIMDDDHLRSSMSALAKVSCMLHVAAMFEDETRIGMKPAPASTSDLRSFLNKLQEMQVRTWSLQYTMLKVGLNQHPELFPKPENDLADYLAAVHQVLGLRKCCKSSNKIFLKMMRVELLKQKNIDNWEDYLGQVLYDLHGLKLGVGIWEVQDHGCEPENLEKRQALQLVGKVTMLANRMSMKDLLKSDLKTTIERMQQAIGSAKSSPQMAHNLRNYSEYLKAPIHPLHLYQALTGSVDLDAVTINTPESAPAKQGWFFLLGMIALTKFKGVDLNRRQTPGATDDLRIGATFLRLQLQYTPDRWDAWFRLAECFDYELDESVLWTADKMNKERAELVKFQRNAIHSYIMALSHSYAWASDPAVLTSLEDDEEALYDMFHEFGMRMYSSSRSPFAMEPFQHAEQNRFFIEAEGAGTYKRIVHNEMTDYQVWKFAAHLFRKAMVGKPKDWKNPYMVAKCLWKMYQKPPEELDEKNRLRRPTVQAVIDALEKTIEVVSSLPKPRHGQDPILEPHYKIVSVVHKLVMRGDMEIQAAANVLQHQPYAPDRGQEISVVNAEDWEAYVVRCLKYLRDKDKSNWQHRIIMRHARILFDEDTDPSDNESSAAAKAAFNVLRESMFTKTMVMNVWKCDAERPGRHHVYTEQYIRYMVRVLDVMKDRVSLEAVLRRIRKKGADFYHFNELWQFGVLAYVKLLRRTFEVPLTEEDAFKTLSQEEFDTVGEKITAWSTTPAAEDNAALTAMKEAVEIKKLNSNLMKAGPIDDLITDCYSAIYLHVKPDLLDSDQQKLPHHPPGDPESKPDSSNPKSTSLLLHALITRDKDKDMTPSALSSLRANSEQPDRDKSERHSLAGDAPPRAASGRAGGGIRRPNILRKAEQAVQAVLRAAEMPPRSVGGATNGAAGGGKTRSRMGSVSNARAGGRAAGEGSGDESGEDEEEAEEGDVEMKDVGDDTGGGGGRRVVVERSVDAGTVKGAAGGDSSYEESDPEGEGESGDRHDHEGEGEGEMEVEQEAGQEEEEGGVGEEHGGDDEIGDDDETEEEHEEGDEGREEGAAPALPEPVMEDADATEEEDEEDEGE
What is the function of this protein?
Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.
What are the official names of this protein?
Histone transcription regulator 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the HIR3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PG030_MONPV
Sequence: MTSLIMDMNRLNLDKLKHENIFSDNIIEDAKEFIFGSRKIYTDSVDDLIELYSLAKYLNNQTLKDVVIERMDYVCKYIGKDNWSTIYSFYKENGLRNSFLRQYINNNIEEICSTDQFLKLDVDSVCDILDNDEIVVTREYTILNMVLRWLENKRVNIDDFTKVMFVIRFKFITYSELTNAIEKIAPEYRQRLQDLYHKKLRVLDIL
What are the official names of this protein?
Protein OPG030.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG030 family.
Protein: THIG_MARMM
Sequence: MEDAVTMDTAFEDKPLVVAGRTFTSRLIIGTGKYKTYAQNAQALEASGAEMITVAIRRVNLSNPDEPRLVDFISPDDYTFLPNTAGCFTGEDAVRTLRLAREAGGWNLVKLEVLSDPKHLYPDMAETLRAAELLIKDGFDVMVYCSDDPVYARKLEEIGCCAIMPLGAPIGSGLGIQNPVNIRLIIEQTKVPVIVDAGVGTASDATVAMELGCDGVLMNTAIAEAKDPIRMARAMRHAVIAGRESYLAGRMPKKRYADPSSPLSGLI
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSA_NEPOL
Sequence: MSILIENISKTFGTFRALDHVNLEVKAGSLVALVGPSGSGKSTLLRMIAGLERADEGKIWLAGRDATYAPIQKRHIGFVFQNYALFKHLNVAKNISFGLEVRQANPNQIRSRVRDLLQLIQLEHMADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDARVRRELRSWLRDLHQEMPVTTVFVTHDQQEAMEVAHEIVVFNQGRLEQVGSPQEIYDHPATPFVMGFMGHINHGVDDVQQSSYFVRPNDVIIQLVPSTNSLSGKVVGMTYGDTSMKLDVDIPQQVPSSDWAPRGSLWRIHLSRRDFNQFNSMLVGGIQIGSVLYVQPRRTEMVRGYSI
What is the function of this protein?
Part of the ABC transporter complex involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: P53_DELLE
Sequence: MEESQAELGVEPPLSQETFSDLWKLLPENNLLSSELSPAVDDLLLSPEDVANWLDERPDEAPQMPEPPAPAAPTPAAPAPATSWPLSSFVPSQKTYPGSYGFHLGFLHSGTAKSVTCTYSPALNKLFCQLAKTCPVQLWVSSPPPPGTRVRAMAIYKKSEYMTEVVRRCPHHERCSDYSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNFMCNSSCMGGMNRRPILTIITLEDSNGNLLGRNSFEVRVCACPGRDRRTEEENFHKKGQSCPELPTGSAKRALPTGTSSSPPQKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGESRAHSSHLKSKKGQSPSRHKKLMFKREGPDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.  Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity).  However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity).  In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.  Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression.  Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1.  LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation.  Regulates the circadian clock by repressing CLOCK-BMAL1-mediated transcriptional activation of PER2.
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Interaction with BANP promotes nuclear localization. Recruited into PML bodies together with CHEK2. Translocates to mitochondria upon oxidative stress. Translocates to mitochondria in response to mitomycin C treatment (By similarity).
Protein: RPOC_ACTP2
Sequence: MKDLVKFLKAQSKSNDDFDVIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLRHRGVICEKCGVEVTQTKVRRDRMGHIELACPVAHIWFLKSLPSRIGLILDMPLRDIERVLYFESYVVTEPGMTDLEKNQLLTEEQFLDAEERWGDEFEAKMGAEGIQALLRDMDLEHQCEMMREELQETNSETKRKKITKRLKLLEAFQQSGNKPEWMVMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLVAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLHQCGLPKKMALELFRPFIYSKLESRGIASTIKAAKKMVEREEPIVWDILAEVIREHPILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLEARALMMSTNNVLSPASGDPIIVPSQDVVLGLYYMTREKVNAKGEGMYFLDPREAEKAYRTGQAELHARVKVRITEHVKNEAGELVAETKLLDTTIGRAILWMIAPKGMPFKVFNQTLGKKAISKLINESYRRLGLKESVILADQIMYTGFAYAARSGASVGIDDMVIPAQKHEIIRAAEAEVAEIQEQFNSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGNPEKQASFNSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVITEDDCGTHEGIVMTPLIEGGDVKEALRDRVLGRVVAEDVLKPGTEEVLIPRNTLIDEKWCDVIDAESVDVIKVRSVVTCNTDFGVCAKCYGRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNAGTIKLTNAKFVTNKEGKIVLTSRNTELTVIDTFGRTKENYKVPYGAVLSKNDGAEVAVGEVVANWDPHTMPVISEVSGRIQFSDIVDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPALRLVDAQGNDILIPSTDVAAQYFLPGKAIVTLDDGAEIEVGEALARIPQESVGTKDITGGLPRVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLVITPAEGEAFEEMIPKWRQLNVFEGEMVQRGDVISDGAETPHDILRLRGVHAVTDYIVNEVQEVYRLQGVKINDKHIEVIVRQMLRKAVITNAYDSEFLEGEQVEVSRVKIANRKRAEEGKPLVEFERELLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGFAYHQNRAKKRNQQEQAVAFEAPVEKLTGSQPMLISKRNSNSLQTMQLKA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RL1_ACIBS
Sequence: MAKLTKRQKAIAAAVEANKVYTLEEAVQVLNSLPAAKFKESLDISVNLGVDPRKSDQVVRGATTLPAGTGKTVRVAVFAQGAQAEAAKEAGADVVGFDDLAESIQGGNLDFDVVIAAPDAMRVVGKLGTILGPRGLMPNPKVGTVTPDVAGAVKNAKSGQARYRVDKAGIIHAAIGQVGFDAAAIRQNVETLVADLKKLKPATSKGVYIKKITLSSTMGPGLTVDVNNVSS
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: FABZ_WOLSU
Sequence: MLYDVQKIKEILPHRFPFLLVDRVTALTSEESIEAYKNITINEEVFQGHFPIKPVYPGVLVIEGMAQAGGVLAFVSMFGEEASNHDEKIVYFMSIDKAKFRVPVTPGDKLVYRLNVLKHKGSIWILEGRAYVDDKLVAEAELKAMVADKEK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_CHRVO
Sequence: MSEQQELQPAFSIEKIYVKDISLEVPNAPQVFLEQAQPEIDMQLASAGQQLDDGFFEVTLTVTVTAKLPEKTMFLCEVAQAGIFQIRNIPGEDLDPILGVACPNILFPYARETVSSVVNRAGFPPVLLAPINFEALYMQQRAQQAEAGNA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPT_MUSCR
Sequence: MRALGAVVTLLLWGQLFAVELGNDAMDFEDDSCPKPPEIANGYVEHLVRYRCRQFYRLRAEGDGVYTLNDEKQWMNTVAGEKLPECEAVCGKPKHPVDQVQRIIGGSMDAKGSFPWQAKMISRHGLTTGATLISDQWLLTTAKNLFLNHSETASGKDIAPTLTLYVGKNQLVEIEKVILHPNHSVVDIGLIKLKQRVLVTERVMPICLPSKDYVAPGRVGYVSGWGRNQDFRFTDRLKYVMLPVADQDKCVVHYEKSTVPEKKNFTSPVGVQPILNEHTFCAGLTKYEEDTCYGDAGSAFAIHDMEEDTWYAAGILSFDKSCAVAEYGVYVRATDLKDWVQETMAKN
What is the function of this protein?
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine.  Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage.  Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response.  Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity).
What are the official names of this protein?
Haptoglobin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPB4_ARATH
Sequence: MALRRLSKSVSSAIKAQYTLSRPSPLLRSRSLSSSPHYTSIGRPTNSFIGKINNSSITHATTTHGQLFPLSSPRRFCTTTAQVNQNEFTEMAWEGLINAFDAARESKQQIVESEHLMKALLEQKDGMARKIFTKAGIDNSSVLQATDLFISKQPTVSDASGQRLGSSLSVILENAKRHKKDMLDSYVSVEHFLLAYYSDTRFGQEFFRDMKLDIQVLKDAIKDVRGDQRVTDRNPESKYQALEKYGNDLTEMARRGKLDPVIGRDDEIRRCIQILCRRTKNNPVIIGEPGVGKTAIAEGLAQRIVRGDVPEPLMNRKLISLDMGSLLAGAKFRGDFEERLKAVMKEVSASNGQTILFIDEIHTVVGAGAMDGAMDASNLLKPMLGRGELRCIGATTLTEYRKYIEKDPALERRFQQVLCVQPSVEDTISILRGLRERYELHHGVTISDSALVSAAVLADRYITERFLPDKAIDLVDEAGAKLKMEITSKPTELDGIDRAVIKLEMEKLSLKNDTDKASKERLQKIENDLSTLKQKQKELNVQWEKEKSLMTKIRSFKEEIDRVNLEIESAEREYDLNRAAELKYGTLLSLQRQLEEAEKNLTNFRQFGQSLLREVVTDLDIAEIVSKWTGIPLSNLQQSEREKLVMLEEVLHHRVIGQDMAVKSVADAIRRSRAGLSDPNRPIASFMFMGPTGVGKTELAKALAGYLFNTENAIVRVDMSEYMEKHSVSRLVGAPPGYVGYEEGGQLTEVVRRRPYSVVLFDEIEKAHPDVFNILLQLLDDGRITDSQGRTVSFKNCVVIMTSNIGSHHILETLRNNEDSKEAVYEIMKRQVVELARQNFRPEFMNRIDEYIVFQPLDSNEISKIVELQMRRVKNSLEQKKIKLQYTKEAVDLLAQLGFDPNYGARPVKRVIQQMVENEIAVGILKGDFAEEDTVLVDVDHLASDNKLVIKKLESNASAEEMAA
What is the function of this protein?
Molecular chaperone that does not seem to be involved in heat stress response or tolerance.
What are the official names of this protein?
Chaperone protein ClpB4, mitochondrial, ATP-dependent Clp protease ATP-binding subunit ClpB homolog 4, Casein lytic proteinase B4.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: METE_VIBVU
Sequence: MTTTTHILGYPRIGEKRELKFAQEKYWRGEIDQAELKKVGAELRHKNWQTQASAGLSFAVAGDFAWYDHVLTTTLLLGHVPKRHRHGFPDLDTLFRVGRGQSQSSCACHGAAASDMTKWFNTNYHYIVPEFSKEDTFEVSWPQLFEEVNEAVQAGHNVKPVLLGPLSYLYLGKEIEDGFDRLTLLPRLLTAYQAILAKLAKQGVEWVQIDEPILALELEKPWLDAFKLAYQVIRSDVKVLLTTYFDSVVDSLDRIVELSVDGLHVDLSAAPEQLDAVLAKLPQNWVLSLGVVNGRNVWRSDVKAQLERLQPVKAALGERLWVASSCSLLHSPVDLELEAGLSAEVRSWFAFAKQKVSEVVLLGKALDGDAAAIAQCEAYSQPIQARKSAAHVHKATVQSRVNAITAELAQRSVPYAERARHQAEVLQLPLLPTTTIGSFPQTSEIRVQRSAYRSGQLSSAEYEQALKGHIADAVKRQEALDLDVLVHGEAERNDMVEYFAENLAGFQTTQFGWVQSYGSRCVKPAIVVADIEREQPITVGWSTYAQSLTSKQMKGMLTGPVTILCWTFPREDISRKAIAQQLALALRDEVSDLQDAGINIIQIDEPAIREGLPLKKRDHQNYLDWAVEAFRISAASARPETQIHTHMCYSEFNEIIESVAALDADVITIETSRSNMELLKAFEEFNYPNEIGPGVYDIHSPNIPSEEWIVDLVKKAAQKIPVERLWVNPDCGLKTRNWPETEAALANLVSAAKRLRKEFAKETTAVNSEAVADVETEA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: PRMA_BACC3
Sequence: MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAGVKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHPTTTMCIRALEKTVQPGDTIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDVVSVGQNSLLEGIEGPVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLRMEDWVAIIARNA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_SULSY
Sequence: MGVEIKGLTVPALLIKLDPSKSLQENIDELKQKLSSAFFKGSYAVVDYNGLELNEESKVEIEKVLKDFNASVLGFQNTKNNKESLKGVTQKKSLKIINKTLRSGQKVEYDGDVLILGDVNPDAYVVSSGSVIVMGNLRGVVHAGANGDETAVVMALKLRPQQIRISNYIARSPDEPDVKAEESNSPEIAYIENNAIVIDKIK
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: RS8_COXBU
Sequence: MMQDPISDMLTRIRNAQAVRKKEVVMPRSKLKMSIANVLKEEGYIVDYREEGDLTKAQLVITLKYHEGESVISEIRRVSSPALQVYKSKDELPKVKNGLGIAIISTSKGVMSDRQARRLGEGGEVLCYVS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: YEDF_SALTI
Sequence: MKNIVPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK
What are the official names of this protein?
Putative sulfur carrier protein YedF.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
Protein: RLMN_LEPBJ
Sequence: MTQEILGEVQTGKIPLKGRTLKELSEIMVSLGEKSFRAKQIYHGLYVNRYESWEQFTTFSKTLKEKLEGLCSLTQLTVVKHLKSVDGTQKFTFASEQGKEFEAVWIPSGDGGRKTICISSQVGCTLNCKFCATAKLEFQGNLKAHEIVDQVLQVEKIVGDNATNVVFMGMGEPFHNYFNVIRAASILHDPDALNLGAKRITISTSGVVNGIRRFIENKEPYNFAISLNHPDPNGRLQIMDIEEKFALSELLQAAKDFTRELKRRITFEYVMIPGVSMGPENANKLVKIARSLDCKINVIPLNTEFFGWRRPTKQEVAEFITLLEPAGVPILNRRSPGKDIFGACGMLASKS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCSB_STAES
Sequence: MMSNIHTNISEWMKMSEETPVIISSRIRLARNLENHVHPLMFPSEQEGYRVINEVQDALSNLTLNRLDTMDQQSKMKLVAKHLVSPELVKQPASAVMLNDDESVSVMINEEDHIRIQALGTDLSLKDLYQRASKIDDELDKALDISYDEHLGYLTTCPTNIGTGMRASVMLHLPGLSIMKRMNRIAQTINRFGFTIRGIYGEGSQVYGHIYQVSNQLTLGKTEEDIIDNLTEVVNQIINEEKQIRERLDKHNSVETLDRVYRSLGVLQNSRIISMEEASYRLSEVKLGIDLNYILLENFKFNELMVAIQSPFLIDDDDNRTVNEKRADLLREHIK
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in proteins.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.