PharMolix/UniProtQA huggingface dataset:
Protein: FUS_NDVI
Sequence: MRSRSSTRIPVPLMLIIRIALTLSCIRLTSSLDGRPLAAAGIVVTGDKAVDIYTSSQTGSIIVKLLPNMPKDKEACAKAPLEAYNRTLTTLLTPLGDSIRRIQESVTTSGGRRQRRFIGAIIGSVALGVATPAQITAASALIQANQNAANILRLKESIAATNEAVHEVTDGLSQLAVAVGKMQQFVNDQFNNTAQQLDCIKITQQVGVELNLYLTELTTVFGPQITSPALTPLTIQALYNLAGGNMDYLLTKLGVGNNQLSSLIGSGLITGNPILYDSQTQILGIQITSPSVGNLNNMRATYLETLSVSTTKGFASALVPKVVTQVGSVIEELDTSYCMETDLDLYCTRIVTFPMSPGIYSCLSGNTSACMYSKTEGALTTPYMALKGSVIANCKMTTCRCADPPGIISQNYGEAVSLIDRHSCNVLSLDGITLRLSGEFDATYQKNISILDSQVIVTGNLDISTELGNVNNSISNALNKLEESNSKLDKLNVKLTSTSALITYIVLTVISLVFGVLSLVLACYLMYKQKAQQKTLLWLGNNTLDQMRATTKI
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with HN at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: ZFPL1_NEMVE
Sequence: MGLCKCPKKKVTNQFCFEHRVNVCEYCLVSSHSRCIVKSYLHWLQDSDYNPVCTLCNGNLSDGDVVRLICYDVFHLSCINNFAQSLPPNTAPAGYTCPNCKNGIFPPEKMVSPVVEQLKQKLSATSWAKAGLGIPVAPLEPLLFSSTVSRKIPEKRPEESLNTSVDHDENKYQRRGAIDWFSRWFGNRVNTKKQTYDDPNASLKRTMMIFFLVILAFVTVTVIFTRVGRNAAANDPFLDPRSNPHIRVEKDS
What are the official names of this protein?
Zinc finger protein-like 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZFPL1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DAPH_THESQ
Sequence: MDAREIIEMIAKAKKKTPIVAYIKGDLAGIDFSSFKFFGDERFGILFGEYEDFKKLLEEHREKIEDYHLEVKARNSALPLADLTKYKARIEPGAIIRDMVEIGEGAVIMMGAVINVGAVIGEGTMIDMNAVVGGRAIIGKKCHIGAGAVIAGVIEPPSAKPVVIEDEVLVGANAVILEGVTVGKGAVVAAGAVVTKDVPPYTVVAGVPARVIKQIDEKTKEKTKIVDELRNLE
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: MSHD_BRAFD
Sequence: MITTTALVPARRSAVRTLLATVTEHDGVSPLDEAALLALDGEDARHLLLTADGAATDTHAAEATAGSAASADPADPADPAAPADPADPADETLLGYVSVLGDGTVQGMVDPAHRRRGHGSALLRAALALRPDAGVWVHGALEGSLAFLTDAGLTETRRLLTLRRDLGGAQPLPSAPAPTLEGLRLDTFEESRDAEAWVAVNVRAFADHPEQGALTRADLEQRLAQPWFDAEDMLVALRDETLVGFVWIKREQPGATDRDAEIYVVATDPSVQGHRVAGHLMATVLERLERDGVPGVELYVEADNAPALRLYENWGFEVSGRDVQLRATERG
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: CCSA_FAGEA
Sequence: MIFFTFEHLFNHISFSIVSIVITIHLITLVVNKIVELDDSLEKGMILTFSCITGLLVIRWIFAGHFPLSDLYESLIFLSWSFYIIHMIPYFKNKKLSAITAPGAIFTQGFATSGFFTQMKQSTILVPALQSQWLMMHVSMMILAYAALLCGSLLSVALLVITFQNNISLFGKRKLLLNESLFIDKIQYVNEKNNILQGTYLFSLINFYRYQLIEQLDRWSSRVISLGFLFLTMGILSGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHIKTNINLKSENSAIVASIGFLIIWICYFGVNLLGIGLHSYGSFILKST
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ARIR_ECOK1
Sequence: MLEDTTIHNAISDKALSSYFRSSGNLLEEESAVLGQAVTNLMLSGDNVNNKNIILSLIHSLETTSDILKADVIRKTLEIVLRYTADDM
What is the function of this protein?
Regulates expression of genes involved in acid-resistance and biofilm formation.  May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition (By similarity).
What are the official names of this protein?
Regulatory protein AriR.
What is the protein family that this protein belongs to?
Belongs to the AriR family.
Protein: IHFA_NEIMA
Sequence: MTLTKAELADILVDKVSNVTKNDAKEIVELFFEEIRSTLASGEEIKISGFGNFQLRDKPQRPGRNPKTGEEVPITARRVVTFHASQKLKSMVEHYYDKQR
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RBFA_STRMU
Sequence: MSNHRIERVGMEIKREVNEILQKKVRDPRVQGVTITDVQMSGDLSLAKVYYTIMSDLASDNQKVQIGLEKAKGTIKRELGKNLTMYKIPDLTFIKDESIEYGNKIDQMLRDLEKRN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_IPOPU
Sequence: MKNVTDSFLSLGPWPSAGSFGFNTDIFATNPINLSVVLGVLIFFGKGVLSDLLDNRKQRILNTIRNSEELRGGAIEQLEKARARLRKIETEAEQFRVNGYSEIEREKLNLIQSTYKTLEQLENYKNETIRFEQQRALNQVRQRVFQQALQRALGTLNSCLNNELHLRTISANIGMLGTMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL35_ORITB
Sequence: MPKLKTKSAVKKRFSLSSSGKLKVTQAGKRHFMRRRTKKQLRNLRSTTTLIGQDAKNIIKYLMPYGVQ
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RRF_DESRM
Sequence: MVKELISSAEDHMKKSVDVVRREFASLRAGRATPSILDKVTVSYYGTPTPLNQLANISVPEARVLVIQPWDKSVIPEVEKAILKSDVGITPSSDGTVIRLIIPQLTQERRTELVKVIKKKAEEGRVAVRNIRRDTNDSIKAKQKDGIPEDEAKRGQDELQKLTDKYVKEIDEMVKAKEQEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_TOLAT
Sequence: MRVLGIETSCDETGIAIFDDQHGILAHQLYSQIKLHADYGGVVPELASRDHIRKTLPLIEAAMQQAGCRSEDLDGIAYTAGPGLVGALLVGATIARSLAMAWNKPAIPVHHMEGHLLAPMLEERVPEFPFIALLVSGGHTLLVRVDGIGHYQILGESVDDAAGEAFDKTAKLLGLDYPGGSALSKLAEQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSQGSDDQTRADIAHAFQTAVVDTLAIKCKRALQATGLKRLVIAGGVSANKELRSQLAELMHKLGGEVFYPRPEFCTDNGAMIAFAGMQRLKAGHTTGLEIVVQPRWNLETLAPVTF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_RICCN
Sequence: MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSHLDKALKNVLKESNTKLTDISTIAATSGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDDAVGEAFDKVAKMLNLAFPGGPEIEKRAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMTLKEINDTVINDIAASFQFTIGEILSSKVQDAIRAYEQITNNFDKKNIVIAGGVAANKYLQKILSSCAKTYGYRLIYPPIHLCTDNAAMIAYAGLERYNNKLFTPLNFCPKARWSLEDISN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_CHLAD
Sequence: MRRANRLRRPAQFRRVRQTGRTFSSAWLTLTVAPGRRDGVRCGFITGRRLGKAVQRNRARRRVREAVRLLLPSLTTGYDLLFAIRSPEVIEAPFSQLQADIIRLLRQACLLTTPETEPVSPVSPTSLPQNERGSP
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: B2LA1_MOUSE
Sequence: MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
What is the function of this protein?
Retards apoptosis induced by IL-3 deprivation.  May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection.  Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11 (PubMed:11888890).
What are the official names of this protein?
Bcl-2-related protein A1, A1-A, Hemopoietic-specific early response protein, Protein BFL-1.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_PAEAU
Sequence: LGIGGLPRGRVVEIYGPESSGKTTVALHAVANAQRAGGIAAFIDAEHALDPDYAAKLGVDTDALLVSQPDTGEQALEIMDMLVGSGSLDIVVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKITGRLSQTKTTAIFINQLREKIGVFFGSPETTTGGKALKFYASVRIDVRRIQTLKEGADSVGNRTKAKIVKNKMAPPFKIAEFDIIYGQGI
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity).
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQSD_PSEAE
Sequence: MGNPILAGLGFSLPKRQVSNHDLVGRINTSDEFIVERTGVRTRYHVEPEQAVSALMVPAARQAIEAAGLLPEDIDLLLVNTLSPDHHDPSQACLIQPLLGLRHIPVLDIRAQCSGLLYGLQMARGQILAGLARHVLVVCGEVLSKRMDCSDRGRNLSILLGDGAGAVVVSAGESLEDGLLDLRLGADGNYFDLLMTAAPGSASPTFLDENVLREGGGEFLMRGRPMFEHASQTLVRIAGEMLAAHELTLDDIDHVICHQPNLRILDAVQEQLGIPQHKFAVTVDRLGNMASASTPVTLAMFWPDIQPGQRVLVLTYGSGATWGAALYRKPEEVNRPC
What is the function of this protein?
Required for the biosynthesis of a number of signaling molecules, such as the quinolone signal 2-heptyl-3-hydroxy-4(1H)-quinolone (PQS), 2-heptyl-4-hydroxyquinoline (HHQ) and 2,4-dihydroxyquinoline (DHQ).  These molecules are required for normal biofilm formation.  Catalyzes the transfer of the anthraniloyl moiety from anthraniloyl-CoA to malonyl-CoA to form 2-aminobenzoylacetyl-CoA (PubMed:24239007).  The first step of the reaction is the formation of a covalent anthraniloyl-PqsD intermediate (PubMed:18728009, PubMed:19694421).  Next, the short-lived intermediate 3-(2-aminophenyl)-3-oxopropanoyl-CoA is formed.  An intramolecular rearrangement of this intermediate can give rise to 2,4-dihydroxyquinoline (DHQ).
What are the official names of this protein?
Anthraniloyl-CoA anthraniloyltransferase, 2-heptyl-4(1H)-quinolone synthase PqsD, PqsD.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_CHLTR
Sequence: MLTLGLESSCDETSCSLVQNGKILANKIASQDIHASYGGVIPELASRAHLQTFPELLTAATQSAGVSLEDIELISVANTPGLIGALSIGVNFAKGLASGLKRPLIGVNHVEAHLYAACMEAPATQFPALGLAISGAHTSLFLMPDATTFLLIGKTRDDAIGETFDKVARFLGLPYPGGQKLEELAREGDADAFAFSPARVSGYDFSFSGLKTAVLYALKGNNSSAKAPFPEVSETQKRNIAASFQKAVFMTIAQKLPDIVKTFSCESLIVGGGVANNSYFRRLLNQICSLPIYFPSSQLCSDNAAMIAGLGERLFCNRTHVSKEVIPCARYQWESACS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNH2_MOUSE
Sequence: MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPSTSWLASGRAKTFRLKLPALLALTARESSVRTGSMHSAGAPGAVVVDVDLTPAAPSSESLALDEVSAMDNHVAGLGPAEERRALVGPGSASPVASIRGPHPSPRAQSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGALPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEDGSQAPDCGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSHIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSAELESGFNRQRKRKLSFRRRTDKDTEQPGEVSALGQGPARVGPGPSCRGQPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGDPPGGEPLTEDGEKSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPAPSLLNIPLSSPGRRSRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSASPLLPVGPVPTLTLDSLSQVSQFVAFEELPAGAPELPQDGPTRRLSLPGQLGALTSQPLHRHGSDPGS
What is the function of this protein?
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel.  Channel properties are modulated by cAMP and subunit assembly.  Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily H member 2, Ether-a-go-go-related gene potassium channel 1, ERG-1, Eag-related protein 1, Ether-a-go-go-related protein 1, MERG, Voltage-gated potassium channel subunit Kv11.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYA_STAS1
Sequence: MKNLKASEIRQNFIDYFVEKGHMVEPSAPLVPIDDDSLLWINSGVATLKKYFDGRETPRKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSEKWMAMEPKLLYVTIHPEDKEAYRIWNEDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEDFGQDDPAEEMYPGGENERFLEVWNLVFSEFNHNKDHTYTPLPNKNIDTGMGLERMASLAQNVRTNYETDLFMPIIHEVEKVSGKTYLENDNYDVAFKVIADHIRTIAFAIADGALPANEGRGYVLRRLLRRAVRFSQSLDINEPFMYRLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEEGLAILNNLVAQAKTSTHEISGKDAFKLYDTYGFPVELTEEIATQENLSIDMQTFEEEMQQQRDRARQARQNSQSMQVQSEVLKKITTDSTFVGYDVMDKASVITDIIQNGELVESAEAGETIYFILRETPFYAVSGGQVADQGTISNENFEIAVTEVTKAPNGQNLHKGEIQFGTVKKNAEVSASVNHKERRSIKKNHSATHLLHAALKEVLGDHVNQAGSLVEADRLRFDFSHFGPMTQEEIDTVERRVNEEIWNSIEVDIQEMPISEAKQLGAMALFGEKYGEIVRVVNMAPFSIELCGGIHVNNTAEIGLFKIVSESGTGAGVRRIEALTGKSAFLYLETIQSQFNAVKSQVKVKSDDQVLEKIVHMQDEEKELTKQLEQKNKEVTSLKMGDITNQVEEINGLKVLATEVDVPNAKAIRETMDDFKSKLQDTVIVLISNIDGKVSLVATVPKALTDKVKAGDIIKNMAPVVGGKGGGRPDMAQGGGTEPKNITESLRFIKDYIKSL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_YOMV
Sequence: MAQFQQTVNMQTLQAAAGRNSLVNDLASRRVYDNAVEELNARSRRPKVHFSKSVSTEQTLLASNAYPEFEISFTHTQQAVHSLAGGLRTLELEYLMMQVPFGSLTYDIGGNFAAHLFKGRDYVHCCMPNLDVRDIARHEGHKEAIFSYLSRLDRQRRPVPEYQRAAFHNYAENPHFVHCDRPFQQCELSTVNRWDTYAIALHSIYDIPADEFGAALLRKNVKICYAAFHFHENMLLDCDSVTLEDIGATFQRAGDKLNFFFHNESTLNYTHSFSNIIKYVCKTFFPASQRYVYHKEFLVTRVNTWYCKFTRVDTFTLFRGVYKTSVDSEEFYKAMDDAWEYKKTLAMLNSERTIFKDSAAINFWFPKVRDMVIIPLFDASITTGRMSRREVLVNKDFVYTVLNHIKTYQAKALTYANVLSFVESIRSRVIINGVTARSEWDTDKAILGPLAMTFFLVTKLSHVQDEIVLKKFQKFDATAKELIWSSLCDALKGVIPSVKETLARGGFVKLAEESLEIKIPELYCTFTDRLVLEYKRTEEFQSCDLSKPLEESEKYYNALSELSVLENLGSFDLDAFKELCQKKNVDPDVAAKVVVAIMNSELTLPFKKPTEEEVAEALSGEVVQDEGLRLSNKAPFPCVSNLKEGLVPACGLCPNGANFDRVDMDISEFHLKSVDAVKKGAMMSAVYTGKIKVQQMKNYVDYLSASLSATVSNLCKVLRDVHGVDPESQEKSGVWDVRRGRWLLKPNAKCHAWGVAEDANHKLVIVLLNWDEGKPVCDETWFRLAVSSDSLVYSDMGKLKTLTSCCRDGEPPEPTAKLVLVDGVPGCGKTKEILEKVNFSEDLVLVPGKEASKMIIRRANQAGITRADKDNVRTVDSFLMHPPKRVFKRLFIDEGLMLHTGCVNFLMLLSHCDVAYVYVDTQQIPFICRVANFPYPAHFAKLVVDEKEDRRVTLRCPADVTYFLNQKYDGSVLCTSSVERSVSAEVVRGKGALNPITLPLEGKILTFTQADKFELLDKGYKDVNTVHEVQGETYEKTAIVRLTATPLEIISRASPHVLVALTRHTTRCKYYTVVLDPMVNVISELGKLSNFLLEMYKVESGTQXQLQIDTVFKGTNLFVPTPKSGDWRDMQFYYDTLLPGNSTILNEFDAVTMNLRDISLNVKDCRIDFSKSVQVPKERPVFMKPKLRTAAEMPRTAGLLENLVAMIKRNMNAPDLTGTIDIEDTASLVVEKFWDAYVVKEFSGTDGMAMTRESFSRWLSKQESSTVGQLADFNFVDLPAVDEYKHMIKSQPKQKLDLSIQDEYPALQTIVYHSKKINAIFGPMFSELTRMLLETIDTSKFLFYTRKTPTQIEEFFSDLDSSQAMEILELDISKYDKSQNEFHCAVEYKIWEKLGIDDWLAEVWRQGHRKTTLKDYTAGIKTCLWYQRKSGDVTTFIGNTIIIAACLSSMIPMDKVIKAAFCGDDSLIYIPKGLDLPDIQAGANLTWNFEAKLFRKKYGYFCGRYVIHHDRGAIVYYDPLKLISKLGCKHIRDEVHLEELRRSLCDVTSNLNNCAYFSQLDEAVAEVHKTAVGGAFVYCSIIKYLSDKRLFKDLFFV
What is the function of this protein?
The replicase small subunit is a methyltransferase active in RNA capping and an RNA helicase.  It also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  May mediate silencing suppression through either inhibition of HEN1-mediated siRNA or siRNA demethylation (By similarity).
What are the official names of this protein?
Replicase large subunit, 182 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus RNA-directed RNA polymerase family.
Protein: KCAB3_HUMAN
Sequence: MQVSIACTEQNLRSRSSEDRLCGPRPGPGGGNGGPAGGGHGNPPGGGGSGPKARAALVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPHSKK
What is the function of this protein?
Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.  Alters the functional properties of Kv1. 5.
What are the official names of this protein?
Voltage-gated potassium channel subunit beta-3, K(+) channel subunit beta-3, Kv-beta-3.
What is the protein family that this protein belongs to?
Belongs to the shaker potassium channel beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_LEPIC
Sequence: MKNIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNGFLLDGFPRTVEQAEALDTLLKNEGKSIDKAINLQVPDAELLKRLLGRAEIEGRADDNEVTIKNRLDNYNKKTLPLLDFYATRKKLSQVNGVGSLEEVTSLIQKELA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RESA_BACC1
Sequence: MKKNRLLFRVIILLILSGAVGFTLYQGYFSKEEKMEIGKEAPNFVVTDLEGKKIELKDFKGKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVKQYDLKFPVAIDKGGEIIKTYGVIPLPTSFLIDKDGKVIQEIKGEQTKEQLEEYLKKITP
What is the function of this protein?
Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis.  May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached.
What are the official names of this protein?
Thiol-disulfide oxidoreductase ResA.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. ResA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane.