PharMolix/UniProtQA huggingface dataset:
Protein: FOLD_CORDI
Sequence: MSAIKLDGNLYRDEIFEDLKGRVNSLREKGIVPGLATVLVGDDPASHAYVRMKHKDCEIVGVKSIRKDLPADVTQEELLAVIDDLNADPECTGYIVQLPLPKHLDENAVLERIDPAKDADGLHPVNLGKLVLNEPAPLPCTPNGAIHLLRRFGVELDGKKVVVIGRGVTVGRPIGLMLTRRSENSTVTLCHTGTRDLAAETREADVIVAAAGKAHMLTADMVKQGAAILDVGVSRVDGKLLGDVHPDVWDVAGAVSPNPGGVGPLTRAFLIRNVVERAERA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DCD_CHLSY
Sequence: MPIKSDRWIRRMALEHGMIEPFVDHQVRRGVISYGLTSYGYDMRVTDHFKVFTNVYNALVDPKQFDPRSFVDIRADYVDIPPNSFALAQSLEYFRIPRTVSCIVIGKSSYARCGIIINVTPLEPEWEGHVTIEISNTTPLPARIYAHEGIGQVLFLESDEPCEVSYADKKGKYQGQTGIVLPRIDP
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ARPB_ECOLI
Sequence: MSQNDIIIRTHYKSPHRLHIDSDIPTPSSEPINQFARQLITLLDTSDLSSMLSYCVTQEFTANCRKISQNCYSTALFTINFATSPIHTENILITLHYKKEIISLLLETTPIKANHLRSILDYIEQEQLTAEDRNHCMKLSKKIHREKNYTPNSKSQW
What are the official names of this protein?
Putative ankyrin repeat protein B.
Protein: RMT2_DEBHA
Sequence: MSDLHELCGFQTRPIGPKYIEDLKFYLKNGIPATYTIEEAYNYTNNIEEEPTTTTTPLHIICSHIPNDASNDEIDIINQMVEILLEYGAGWCLTDINDDTPGCILIRRKLNNTPIYNQVVAAGVRAELLLRKVSEYDMEIIEDTDDLNHEQFEGIQGEETTEEERKEEEPSNTSDIIDEQKVEQPKEDLKEDPSSNQETYLKTKLEYKDGALVTKDRKDGVMMSWETDLMRMGCDSLFKGASIDGEIDDEVNILNIGFGMGIIDTMINNKNPTKQYICEAHPDVLAKLRLDGWYEKQNVVILEGRWQEQLNKLLSEGNVFFNGIYYDTYSEHYEDMLELFDIVVGILKPHGVFSFFNGLGADRQVVYEVYKQLVEMDLANYGLICKFEQIEVPESTLQLEVQNSTDNKSVWDDIKRAYWTCPTYYHPEARFMDV
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins.  Monomethylates ribosomal protein L12.
What are the official names of this protein?
Protein arginine N-methyltransferase 2, Protein-arginine N5-methyltransferase, Type IV protein arginine N-methyltransferase, Type IV PRMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TIAS_IGNAA
Sequence: MYENFCIYHIGLDDFDLLSYGCTTHVATYLLHSLAKRFSSIVFIDYPNLVRLNPSIPWKTRGNGAIAIRIAMECTDLNNLLEAAEDIIDEYYEKYGVRTKDVVSSDREPGLVVVRNGIVNDMGSLYITALTDVLLPEIVKKKIDKYGRENIVVSKRYCGRGIVGAAASVGWIAIDSDYTYELLVYRSEKFYSLDRCVNEESVKYFDSITKDRTFNNIDVDSNRILITSHGRDPILYGVRGEDPEVLLKALDIIRVCEPISSWTIFRTNQATDAHAIDRSVSSLRVYRTGKIRVTISSKPSIGMGGTVIINGFDATGSITLAFFRPSYLNRYASMLIPGDVIEANGHVKPWNIGPVFHVEKFSVLKLAPLYRCKAPRCPYCRKRLTKMGRGKGYKCDKCGYSVINPDLECEYIERKIRLGLYIPPPRALKHLIKPIERYGKEKYRHRYPIELKLSQITKILETSI
What is the function of this protein?
ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
What are the official names of this protein?
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS, tRNA(Ile2)-agm2C synthetase, tRNA(Ile2) agmatidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the TiaS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_RICBR
Sequence: MTSNLKYKRVLLKVSGEALMGDKQFGHDYDTIKKIAGDIKELIDSGVEVAIVVGGGNIYRGINAALVGMDRASADYIGMLATVINALTLQNVMESLNIYTRVLSAIPMMSVCEPYIRRRAKRHMEKGRVVIFAGGTGNPFCTTDSAAVLRAIEMNCDVLLKATQVDGVYDSDPKKNPNAKKYFTINYKDVITNNLQVMDLATIAIARENKLPIRVFSIKEQGNIAKVVQDQGEYTTIEE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T23O_BACCZ
Sequence: MKENEKVIMEKGIHTDFKENMTYGEYLQLDSLLSSQKRLSDHHDEMLFIVIHQASELWMKLILHELNAAIESIKQDKLQPAFKMLARVSKIQSQIIQSWDILATLTPSEYIEFRDSLGQASGFQSYQYRMIEYALGYKTPHALKIYEKDPELHARLHAALHAPSLYDVAIQALVKEGFPIHKDVLNRDITQPYEEDATVEAAWLEVYADVKKYWNLYQLAEKLIDIEDWLQQWRFRHMKTVERIIGHKMGTGGSSGVSYLKRVLDQRFFPELWNVRTKL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: RS20_LACCB
Sequence: MPQIKSAIKRVKTQEAARVRNIAQMNAMRTAVKKFKTATEQNADNSQDLYKAAARAIDMANSKGLIKKNKAGRDKSRLSALLNK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RNZ_CLOD6
Sequence: MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSMKLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMRNLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDIDKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPDFIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIPSMYLENATNVFENTILGEDRLSLRLNFDE
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: APOC2_MICOH
Sequence: MGSRFLLALFLILLVLGCEVQAAQQLQQDDPGSSALLDKVQESISSYWDTAKAAAQDLYQKTYLTSVDEKLRDMYSKSSAAMTTYASIFTDQILTLLKGE
What is the function of this protein?
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma.  Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
What are the official names of this protein?
Apolipoprotein C-II, Apo-CII, ApoC-II, Apolipoprotein C2.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLADA_STRSD
Sequence: MTSELALFGGTPVRTEPFPDGPRFRERDLERIREVLESGSLGGIPFPNRTHRAFAEQFCGRLGARHGVLVANGTVSLSVALRALGVHAGDEVITTGYTWMGTAASIVHINAVPVLVDIDPNTWCIDPAAVEAAITPRTRAIVPVHLANQIADLDALLEIARKHDLVVLEDCAHAHFAEWRGRCVGTHGDAGSFSFESSKIMTSGEGGFLVSGDETTHHRAMSLVNCGRKEEGYDSFEGRMLGWNNRATELQAAFLIGQVEQHDELHAQRKSNVELLTKGLTEIGGFTPVGDDDPRVTRRQYYEVLYRFDPEQWAGVHRDRVLEALLAEGVEFEGITFYPPLHRDSLFTVSAEDWPMIRDRYGDRMGPEDFHLPVSERAAYDESVWVHHSLLTGPATDVDQILEAVAKVRRNVDALR
What is the function of this protein?
Catalyzes the transamination of 3-amino-2,3-dideoxy-scyllo-inosose (amino-DOI) into 2-deoxystreptamine (DOS).
What are the official names of this protein?
Putative L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase, Putative L-glutamine:amino-DOI aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. L-glutamine:2-deoxy-scyllo-inosose/scyllo-inosose aminotransferase subfamily.
Protein: PUR2_YARLI
Sequence: MSLRILLVGNGGREHALAWKLAQSPLVERIFVAPGNGGTDNPQGKIENIAIGSSQKDFAKLVEFAQSKDVGLVIPGPEQPLVEGIETHFRKVGIPVFGPSEKAAVMEGSKTFSKDFMKKHNIPTAAFENFTDYNKAVDYVKKVGHRVVIKASGLAAGKGVLIPTSTEEAIAAVKEVMQDKAFGEAGDEVVIEEFLEGDELSILAFSDGYTVVDMPPAQDHKRIGDGDQGLNTGGMGAYCPAPIGTPALLQEIKESILQPTIDGMRRDGIPFVGMLFTGIMLTPDGKPKVLEYNVRFGDPETQTILPLLSDDTDLAEVMLACVERRLDAVTLRVKPDAHAVTVVMSAGGYPESYKKGDAITVGGLPEQTYIFHAGTASENGQVITAGGRVIASTAVAPTLKDAVAQAYKGADAVEFNGKYNRKDIAYKAFRDAEKTSGGITYAQAGVSIDNGNKLVQQIKEKVKSTARPGTDSVIGGFGGLFDLKAAGFRDPLLVGATDGVGTKLKIAQSIDKHDTVGIDLVAMNVNDLVVQGAEPLVFLDYYATGKLDVNAAAAFVGGVADGCIQAGCALIGGETAEMPGIYYGNDYDANGTSIGAVERDAVLPRMDEIAKGDAILGLASSGVHSNGFSLVRKIIEHAGLTYTDACPWDQSKSLGEALLTPTRIYVKQLLPVINAKLTSALAHITGGGLVENIPRILPENYSAKIDVSTWPLPPVFQWLGKAGNVPKEDISKTLNMGIGMILVVKQEKVAEVTQLLEKVGEKVYQIGEIVPDNDVDEKTVLINTENWY
What is the function of this protein?
Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
What are the official names of this protein?
Bifunctional purine biosynthetic protein ADE1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: Y1333_NEIMB
Sequence: MRYKPLLLALMLVFSTPAVAAHDAAHNRSAEVKKQTKNKKEQPEAAEGKKEKGKNGAVKDKKTGGKEAAKEGKESKKTAKNRKEAEKEATSRQSARKGREGDKKSKAEHKKAHGKPVSGSKEKNAKTQPENKQGKKEAKGQGNPRKGGKAEKDTVSANKKVRSDKNGKAVKQDKKYREEKNAKTDSDELKAAVAAATNDVENKKALLKQSEGMLLHVSNSLKQLQEERIRQERIRQARGNLASVNRKQREAWDKFQKLNTELNRLKTEVAATKAQISRFVSGNYKNSQPNAVALFLKNAEPGQKNRFLRYTRYVNASNREVVKDLEKQQKALAVQEQKINNELARLKKIQANVQSLLKKQGVTDAAEQTESRRQNAKIAKDARKLLEQKGNEQQLNKLLSNLEKKKAEHRIQDAEAKRKLAEARLAAAEKARKEAAQQKAEARRAEMSNLTAEDRNIQAPSVMGIGSADGFSRMQGRLKKPVDGVPTGLFGQNRSGGDIWKGVFYSTAPATVESIAPGTVSYADELDGYGKVVVVDHGENYISIYAGLSEISVGKGYMVAAGSKIGSSGSLPDGEEGLYLQIRYQGQVLNPSSWIR
What are the official names of this protein?
Uncharacterized protein NMB1333.
What is the protein family that this protein belongs to?
Belongs to the peptidase M23B family.
Protein: SYQ_SERP5
Sequence: MSEAEARPTNFIRQIVDEDLASGKHKSVHTRFPPEPNGYLHIGHAKSICLNFGIARDYQGQCNLRFDDTNPVKEDIEFVESIKHDVEWLGFEWSGNVRYSSDYFDQLHNYAVELINKGLAYVDELSPEQIREYRGSLTAPGKDSPYRGRSVEENLALFEKMRNGEFAEGTACLRAKIDMASSFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPCHPRQYEFSRLNLEYAIMSKRKLNLLVTEKIVEGWDDPRMPTVSGLRRRGYTAASIREFCQRIGVTKQDNNVEMMALEACIREELNENAPRAMAVLDPVKVVIENLTTGVEMVTMPNHPSKPEMGSREVPFSRDIYIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERIEKDAEGEITTIFCSYDPDTLSKDPADGRKVKGVIHWVSAEHALPAEIRVYDRLFSVPNPAAAEDFLTTINPESLVIKHGFVEPSLAAAQPEKAYQFEREGYFCADNRHSSAEHLVFNRTVGLRDTWAKIGA
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y830_STAAN
Sequence: MLHLHILSWVLAIILFIATYLNISKNQGGSPFFKPLHMILRLFMLLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHKMFWITMALIIITMVLGVILPLGPISKLFGIG
What are the official names of this protein?
UPF0344 protein SA0830.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URED_ACTPJ
Sequence: MQSKLLLSTKLTSQGKTQLDQYFVSPPFKVMTLPAYDDAWQNGLNAMQMSSSPGLLASDLFDIEISLADDTALSLNTQAFTRVQSMNEGDYATQKTCIKLGKNSRLFYLPHPLVLHKDSSFKQTTEIEMSEQSELIYGEIVAIGRVLNGERFAFRHFASYLRISYQNRPIIADRIQWLPAKMALTSLSQMEDFSHQGSLTYVNLAKNAVEIKAMVSELQALAAEQKNMLIGVSQLNEGGLMVRVLAHRADIIQHLFERIGQVLKAQSNIV
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOYF_BACSU
Sequence: MIAKMMEALDGERFDIIMEKTLKGMTRVMIWGCLPYFLYVLIRMFTN
What are the official names of this protein?
Uncharacterized membrane protein YoyF.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: UXAC_SALCH
Sequence: MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDPIDSLEYHRQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLRKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDHGIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: RUVB_DEHM1
Sequence: MSEEKERLISGKLAADDAKLDTSLRPRCLSDFIGQKRLKDNLGVAIQAAKQRGEALDHVLLYGPPGLGKTTLSHIIALEMGVNIRITSGPAIERQGDLAAILTNLKPFDILFIDEIHRLSRNVEEVLYPAMEDYALDIMVGKGPGARSLRLKLPHFTLIGATTRYAMLSAPLRDRFGSIFRLDFYDEDAIHDIVSRSAHILGVEAEENGIRQIACRSRGTPRVANRLLRRVRDYAQVKGNGLITGDMAAESLACLEVDRLGLDEIDHKVLKTIIHKFGGGPVGLETIAAAISEEADTIMDVYEPYLLQLGFLERTPRGRQATRLAYQHLNIPYPADKNNQQGLWAENGT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RS15_SALAI
Sequence: MALDQQAKAKIRAEYATVEGDTGSPEVQVAVLTKRIADLTEHLKVHKHDHHSRRGLLLLVGRRRRLLNYVQKRDINRYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RECR_BIFLS
Sequence: MALAYDGAIQRLIDAFGRLPGIGPKGAQRIAFYMLSAPEDEARDLAEAIEEVKAKIRFCDICGNVCESSPCPVCADPRRDRSVICVVEEPKDVMSIERTREYRGLYHVLGGAINPMANVGPADLRIPSLLKRLEGDEVKEVIMALDPNIEGEATTSYLTQLLRPVGVKVTRLASGLPVGSDLEYADEITLGRALAGRREA
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: APRX_BACSU
Sequence: MFGYSMVQMVRANAHKLDWPLRETVLQLYKPFKWTPCFLHKFFETKLQNRKKMSVIIEFEEGCHETGFQMAGEVLQKEKRSKLKSRFNKINCCSAEVTPSALHSLLSECSNIRKVYLNREVKALLDTATEASHAKEVVRNGQTLTGKGVTVAVVDTGIYPHPDLEGRIIGFADMVNQKTEPYDDNGHGTHCAGDVASSGASSSGQYRGPAPEANLIGVKVLNKQGSGTLADIIEGVEWCIQYNEDNPDEPIDIMSMSLGGDALRYDHEQEDPLVRAVEEAWSAGIVVCVAAGNSGPDSQTIASPGVSEKVITVGALDDNNTASSDDDTVASFSSRGPTVYGKEKPDILAPGVNIISLRSPNSYIDKLQKSSRVGSQYFTMSGTSMATPICAGIAALILQQNPDLTPDEVKELLKNGTDKWKDEDPNIYGAGAVNAENSVPGQ
What is the function of this protein?
Displays serine protease activity.  Seems to have a broad substrate specificity.
What are the official names of this protein?
Serine protease AprX.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Is leaked to the culture medium during the late stationary phase owing to cell lysis.
Protein: KTHY_CLAM3
Sequence: MTGVFITLEGGDGVGKSTQSALLRGWLEDEGHEVVVTREPGGSELGVEIREIVLHRRGHIAPRAEALLYAADRAHHVETVVRPALDRGAVVLQDRYLDSSVAYQGAGRVLDAGEIRELSLWAAQGLLPDLTVLLDLDQAAARVRLDAARTRFDRLESERADFHERVRQAFLGLAGAEPERFLVVDAARPREEIAAAIRTRAQALIAAGASA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: MURI_HELPY
Sequence: MKIGVFDSGVGGFSVLKSLLKAQLFDEIIYYGDSARVPYGTKDPTTIKQFGLEALDFFKPHQIKLLIVACNTASALALEEMQKHSKIPVVGVIEPSILAIKRQVKDKNAPILVLGTKATIQSNAYDNALKQQGYLNVSHLATSLFVPLIEESILEGELLETCMRYYFTPLEILPEVVILGCTHFPLIAQKIEGYFMEHFALSTPPLLIHSGDAIVEYLQQNYALKKNACAFPKVEFHASGDVVWLEKQAKEWLKL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: FA83D_HUMAN
Sequence: MALLSEGLDEVPAACLSPCGPPNPTELFSESRRLALEELVAGGPEAFAAFLRRERLARFLNPDEVHAILRAAERPGEEGAAAAAAAEDSFGSSHDCSSGTYFPEQSDLEPPLLELGWPAFYQGAYRGATRVETHFQPRGAGEGGPYGCKDALRQQLRSAREVIAVVMDVFTDIDIFRDLQEICRKQGVAVYILLDQALLSQFLDMCMDLKVHPEQEKLMTVRTITGNIYYARSGTKIIGKVHEKFTLIDGIRVATGSYSFTWTDGKLNSSNLVILSGQVVEHFDLEFRILYAQSKPISPKLLSHFQSSNKFDHLTNRKPQSKELTLGNLLRMRLARLSSTPRKADLDPEMPAEGKAERKPHDCESSTVSEEDYFSSHRDELQSRKAIDAATQTEPGEEMPGLSVSEVGTQTSITTACAGTQTAVITRIASSQTTIWSRSTTTQTDMDENILFPRGTQSTEGSPVSKMSVSRSSSLKSSSSVSSQGSVASSTGSPASIRTTDFHNPGYPKYLGTPHLELYLSDSLRNLNKERQFHFAGIRSRLNHMLAMLSRRTLFTENHLGLHSGNFSRVNLLAVRDVALYPSYQ
What is the function of this protein?
Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117).  May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692).  May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22 (PubMed:18485706).
What are the official names of this protein?
Protein FAM83D, Spindle protein CHICA.
What is the protein family that this protein belongs to?
Belongs to the FAM83 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Primarily cytoplasmic during interphase, but at prophase, associates with spindle microtubules, with a clear concentration toward the spindle poles. It persists on spindle microtubules through metaphase and anaphase.
Protein: ATPA_ANAD2
Sequence: MEIRADEISRIIREQIKDYGKKVEVAETGSILSQADGVARIYGLAGAAAGELLEFPGGIRGLVLNLEEDNVGAAIMGPYEHIREGDPVKRTGLIAEVPVGEELLGRVVDGLGNPIDGRGPLNAKHHRKIEIKAPGIVKRKSVHEPMQTGLKAIDALVPIGRGQRELILGDRQTGKTAVAIDTILNNKGNNLYCFYVAIGQKQSTVARVVDTLKKYGAMEYTTVISASASDPAPMQYLAPYTGVTMAEYFRDSGRHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDKEGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESNLFYQGVRPAINVGISVSRVGGSAQIKAMKQVAGSLKLDLAQYRELAAFAQFGSDLDKATQETLARGERLVELLKQGQYAPLSVEKQVIQIYAGTQKDTDGQNWIRAVPTEQVVRYMRELIEFLDARHPGIAKAIAEKKALDDGIRKDLDAALREFAGIFKIEG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FOLM_KLEP7
Sequence: MAEQQPRPILITGAGRRIGLALAHHFLQQRQPVIVSYRTPYPAIDGLREAGALCLQADFSSDDGILTFAEAVKSHTDGLRAIIHNASDWMAEKPGVPLSTVINRMMQIHVHAPYLLNHALEALLRGHGHAASDIIHITDYVVERGSDKHIAYAASKAALDNMTRSFARKLAPEVKVNAIAPSLIMFNEGDDEAYRQQALDKSLMKIAPGEKEISDLIDYLFTSRYVTGRSFAVDGGRPLR
What is the function of this protein?
Catalyzes the reduction of dihydromonapterin to tetrahydromonapterin.  Also has lower activity with dihydrofolate.
What are the official names of this protein?
Dihydromonapterin reductase, H(2)-MPt reductase, Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FolM subfamily.
Protein: TRUD_HYDCU
Sequence: MPNPISLSHFAFAYGRPENTAVLKAEPADFQVDEHIAYTLSGEGEHLWVWVQKIGQNTDWVAKQIASWAGITAKEMGVAGKKDRQAITRQWMSLHLPGKQAPDIGSLDVPGVTLLKAMRHHRKLQTGGLSGNRFTLVLREINGNLDQIETRLQKIAGKGVPNYFGEQRFGNDFQNLAKATALFQGQIKSPKRHQKSLYISAARSWIFNEILSQRVRQGTWNRAISGDVFQLEGSQKWFADDSDPSLSKRVEEKGLHPTGALTGRGVLPSQSDAFQVEQAVLEKHPFWQAGLEKLGLKQERRALRVLPKEMHWEWLDQQTLSVGFDLPAGSYATMVMRELFEVKLED
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: Y059_ARCFU
Sequence: MYRYPVEVIADTYLSKVGGYSYELDRNEIGINVKALEMNTSIIANETLATLKRFEEIRPYFLRRKFVVVGIEESMDCYEMSANGEVVLPEEMEGSMEVGESVIVNTVEAFRIDGDYSNIIKAIKWRLDNQILRN
What are the official names of this protein?
Uncharacterized protein AF_0059.
Protein: RK1_CYAPA
Sequence: MKKRSRRMQELVGKVEEQLYEPLEAIQLLKQISTAKFIETVEVHCRLGIDPKYNDQQLRATVTLPNGTGQTLRVAVITRGEKINEASTAGADLVGAEELIDEIQNGRLDFDCLIATPDMMPQVAKLGRVLGPRGLMPSPKGGTVTFDLAQAINDFKAGKLEFRNDRTGIVHVLFGKANFSEEALLGNLKAVQEAVDRNRPSGVKGKYWKSIYITSTMSPSIEVDYNLLRDLKLTENT
What are the official names of this protein?
50S ribosomal protein L1, cyanelle.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: LUXS_BACC7
Sequence: MPSVESFELDHTIVKAPYVRHCGVHNVGSDGIVNKFDIRFCQPNKQAMKPDVIHTLEHLLAFNLRKYIDRYPHFDIIDISPMGCQTGYYLVVSGTPTVREIIDLLELTLKDAVQITEIPAANETQCGQAKLHDLEGAKRLMNFWLSQDKDELEKVFG
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: YIDD_STRPS
Sequence: MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFKGVLMGLARILRCHPWSKTGKDPIPDHFSLKRNQEGE
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.