PharMolix/UniProtQA huggingface dataset:
Protein: CCA_VIBVY
Sequence: MEVYLVGGAVRDKLLGIPVYDQDWVVVGATAEQMLNAGYSPVGKDFPVFLHPKTKQEYALARTERKTGQGYKGFECFFSPDVTLEEDLLRRDLTINAIAMDSQGVLYDPYGGQQDLQDRILRHVSEAFVEDPLRVLRVARFAAKLAPLGFRVADETMQLMQSIVASGELSALTAERVWQEWHKSLLTPAPQQFLAVLRQCGALAVVLPEIDALFGVPQPEKWHPEIDTGIHTLLVAEQAAKLSSSAVVRFAAQVHDLGKGVTPPSEWPSHKMHCHTGLKLIKQLCERVRVPNEFRDLALMVCEQHSNIHRAAELKPQTMVKIFNKLDVWRKAERLNDILLCCQADHAGRQGLQDHPYPQAERIQLAYQAALSVEVQSVIQDGFKGPAIRDEQERRRIEAVKAALLNA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: NDUA2_BOVIN
Sequence: MAAAAAIRGVRGKLGLREIRIHLCQRSPGSQGVRDFIEKRYVELKKANPDLPILIRECSDVQPKLWARYAFGQEKNVSLNNFSADQVTRALENVLSSKA
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2, Complex I-B8, CI-B8, NADH-ubiquinone oxidoreductase B8 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA2 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SYDND_MARMS
Sequence: MRSHYCGELNASNISQEITLCGWVHRRRDHGGVIFLDVRDREGITQVVFDPDRAESFALADSVRNEFVVKLKGLVRARPEGTVNPNMNTGEIEVLGTELEILNAAKTPPFQLDEHQSVGEDVRLKNRFIDLRRPEIQQKMRFRSKVTSVLRRYLDGNGFLDIETPILTRATPEGARDYLVPSRTQQGSFFALPQSPQLFKQLLMVSGFDRYYQIAKCFRDEDLRADRQPEFTQVDIETSFMSEQEIMAMTEEMIVGLFKELMDIDLGTFPRMPYSEAMETYGSDKPDLRIPLTIVTVSDLMAGVDFKVFSGPATDPKGRVAALKVPGGNALTRKQIDDYTKFVSIYGAKGLAYIKVNDKSNLEEGLQSPIVKFLPVEVRAALLERLEAEDGDLIFFGADSAKIVNEALGALRCKLGDDLNLYTCKWAPLWVVDFPMFEETSDGGITAIHHPFTAPSCSPENLKASPLTALSQAYDMVLNGTELGGGSIRIHQSSMQETVFELLNITKEEQEEKFGFLLDALKFGAPPHGGLAFGLDRLVMLMTGSSSIRDVIAFPKTQSATCLLTQAPGEVSEKQLKELNIRIRKPVVES
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_BACC2
Sequence: MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAADELAGHDVDVCTVIGFPLGASTTETKAFETKDAIAKGATEVDMVINVGALKDGDNELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGVKASGGVRTREDADKMVAAGASRVGASASVAIVLNDAKGATDNY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAB_ACTSZ
Sequence: MKYIQAFMNNFLGNSPDWYKVTIGVFLVINPFIFWFHPFIAGWLLVAEFIFTLAMALKCYPLQPGGMLALEAVTIGMTSPEHVKAEILANFEVILLLMFMVAGIYFMKQLLLYAFTKLLLRIRSKLTLSLAFCLTAAFLSAFLDALTVIAVIISVAMGFYGVYHKVASGGTFNDPSDITNDAKIKQNMETLEQFRAFLRSLMMHAAVGTALGGVMTLVGEPQNLIIAEQAGWGFKEFFFRMSPVTLLTLISGVVTCITVERLRLCGYGEKLPRKVWGVLAKFDRAHEEQMTTQDRVKLGVQVFVGIWLIIGLAFHLASVGLIGLTVIILTTAYCGITDEHAIGRAFQESLPFLSLLVVFFSVVAVIIDQHLFAPVIELVLNASESVQLLLFYIFNGVLSAISDNVFVATVYINEAKNALTAGAISPYQFEMISVAINTGTNLPSVATPNGQAAFLFLLTSSISPLIRLSYGRMVYMALPYTIVLSIVGLLAVEYVLPGMTQWLAQVGLIESPHIPMTSVFGH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APYC1_BPBSP
Sequence: MLHTTQIRMVGTGSAFSKKFYNNSALVTFTNGYNLLIDCGHSVPKGLHDADIPLESIDGILITHTHADHIGGLEEVALYNKFVLGGRKIDLLVPNTLVESLWENSLKGGLRYSDTYDDLSLSDYFTVRSLKTFTSGAARTQLEENIAIKLYPTFHVSHMASYAVGLEDRGEDKVFYSSDTIFDEYLIDYALTYSWVFHDCQFFTGGVHASLDELLNYIPEEDQDRVFLMHYGDNMEDFFTKTGRMRFALQGRTYIL
What is the function of this protein?
Counteracts the host Pycsar antiviral defense system.  Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
What are the official names of this protein?
Anti-Pycsar protein Apyc1, Apyc1.
What is the protein family that this protein belongs to?
Belongs to the anti-Pycsar protein Apyc1 family.
Protein: T1MP_ECOLX
Sequence: MKMTSIQQRAELHRQIWQIANDVRGSVDGWDFKQYVLGALFYRFISENFSSYIEAGDDSICYAKLDDSVITDDIKDDAIKTKGYFIYPSQLFCNVAAKANTNDRLNADLNSIFVAIESSAYGYPSEADIKGLFADFDTTSNRLGNTVKDKNARLAAVLKGVEGLKLGDFNEHQIDLFGDAYEFLISNYAANAGKSGGEFFTPQHVSKLIAQLAMHGQTHVNKIYDPAAGSGSLLLQAKKQFDDHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFDIKLGNTLTEPHFRDEKPFDAIVSNPPYSVKWIGSDDPTLINDERFAPAGVLAPKSKADFAFVLHALNYLSAKGRAAIVCFPGIFYRGGAEQKIRQYLVDNNYVETVISLAPNLFFGTTIAVNILVLSKHKTDTKVQFIDASELFKKETNNNILTDAHIEQIMQVFASKEDVAHLAKSVAFETVVANDYNLSVSSYVEAKDTREIIDIAELNAELKTTVSKIDQLRKDIDAIVAEIEGCEVQK
What is the function of this protein?
The subtype gamma methyltransferase (M) subunit of a type I restriction enzyme.  The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues of the sequence 5'-CCAN(7)ATGC-3'.  In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site.  Whether the DNA is cut or modified depends on the methylation state of the target sequence.  When the target site is unmodified, the DNA is cut.  When the target site is hemimethylated, the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated.  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage.
What are the official names of this protein?
Type I restriction enzyme EcoprrI methylase subunit, M protein, Type I methyltransferase M.EcoprrI, M.EcoprrI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: RNH_METEP
Sequence: MGPMRTIVYADGGCDPNPGPGGWAAVIQAPTGTIELYGGELATTNNRMELTAAIRALEHFPEGAAIEMRCDSQYVVKSVTEWMRGWKARGWRTATGPVKNIDLMQRLDALAAARDVRWTWVRGHAGEAGNERADRLATLGRREALSGKTSGEAMPLPADAAPALAPAQPVQSKTVQVALSADLANALSRAAGRAGITPQAYLEDAVRLALELKPPGVARVRAELQKAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLN1_ALLSA
Sequence: MVESYKKIGSCNKMPCLVILTCIIMSNSLVNNNNMVQAKMTWTMKAAEEAEAVANINCSEHGRAFLDGIISEGSPKCECNTCYTGPDCSEKIQGCSADVASGDGLFLEEYWKQHKEASAVLVSPWHRMSYFFNPVSNFISFELEKTIKELHEVVGNAAAKDRYIVFGVGVTQLIHGLVISLSPNMTATPDAPESKVVAHAPFYPVFREQTKYFNKKGYVWAGNAANYVNVSNPEQYIEMVTSPNNPEGLLRHAVIKGCKSIYDMVYYWPHYTPIKYKADEDILLFTMSKFTGHSGSRFGWALIKDESVYNNLLNYMTKNTEGTPRETQLRSLKVLKEVVAMVKTQKGTMRDLNTFGFKKLRERWVNITALLDQSDRFSYQELPQSEYCNYFRRMRPPSPSYAWVKCEWEEDKDCYQTFQNGRINTQNGVGFEASSRYVRLSLIKTQDDFDQLMYYLKDMVKAKRKTPLIKQLFIDQTETASRRPFI
What is the function of this protein?
Able to cleave the C-S bond of sulfoxide derivatives of Cys to produce allicin, thus giving rise to all sulfur compounds which are responsible for most of the properties of garlic, such as the specific smell and flavor as well as the health benefits like blood lipid or blood pressure lowering.
What are the official names of this protein?
Alliin lyase 1, Alliinase-1, Cysteine sulphoxide lyase 1.
What is the protein family that this protein belongs to?
Belongs to the alliinase family.
What are the subcellular locations of this protein?
Vacuole.
Protein: SYGB_HELP2
Sequence: MHSDELLVEILVEELPAQALLNEYKEMPKKLHALFQKRALEVGTIEVFYTPRRLCLLIKDFPLLTQETKEEFFGPPVKIACNHQDKMQGLNALGLGFYQKLGLKDHQHFQTAFKNNKEVLYHAKIHAKEPTKDLIMPIVLEFLEGLNFGKSMRWGNVEKSFIRPIHNICVLFNGENFNNIEVKEYGFKTKQATKTHRQEGFDFIQVDSPKAYFEVLEKNHVILDPKKRKAKILQEIKELETKHHIIVEIDRDLLDEVVAITEYPSVLLGEFDKAFLKLPSEIITTSMKENQRYFAVFSQKSQEESPTLHNGFIVVSNAISKDKQKIIAGNQKVLKARLSDAVFFYENDLKKPLDNAPLESVVFVQGLGTLKDKMERESTIAQYLTQKYAPSLNMPLEKALELIGRAVKIAKADLLSEVVYEFSELQGIMGYYYALKQNENELVALSLKEQYLPASENAPLPSSVFSAIVALSLKLDSLFSLFSVGKIPSGSKDPFALRRLSFGLLKIIAHYGLEFDLKADLKNLFEKVGIYQSFDLEILEKFLLERFNNLIDCNPSIIRSVLNTNERDIVKIIQKVKALKRFLDDPKNAQKKELLFSAFKRLANINKDRNPNESSGFSISLFKELQEHALFEAFNAIKTSAFESLDSKIEAYFGLHAPLEEYFKSVLVMDKDIEIQKNRKNFLWGVYQSFLEIGDIKEIAI
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LKTCB_MANHA
Sequence: MNQSYFNLLGNITWLWMNSPLHKEWSCELLARNVIPAIENEQYMLLIDDGIPVAYCSWADLNLENEVKYIKDISSLTLEEWQSGDRRWIIDWVAPFGHSQLLYKKMCQKYPDMIVRSIRFQPNQKSVGKISYFKGGKLDKKTAKKRFDTYQEELATALKNEFNFIKK
What is the function of this protein?
Involved in fatty acylation of the protoxin (LktA) at two internal lysine residues, thereby converting it to the active toxin.
What are the official names of this protein?
Leukotoxin-activating lysine-acyltransferase LktC serotype A11, Leukotoxin C, Toxin-activating protein C.
What is the protein family that this protein belongs to?
Belongs to the RTX toxin acyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRA6_PSEAI
Sequence: MINVAILSAIRRWHFRDGASIREIARRSGLSRNTVRKYLQSKVVEPQYPARDSVGKLSPFEPKLRQWLSTEHKKTKKLRRNLRSMYRDLVALGFTGSYDRVCAFARQWKDSEQFKAQTSGKGCFIPLRFACGEAFQFDWSEDFARIAGKQVKLQIAQFKLAHSRAFVLRAYYQQKHEMLFDAHWHAFQIFGGIPKRGIYDNMKTAVDSVGRGKERRVNQRFTAMVSHYLFDAQFCNPASGWEKGQIEKNVQDSRQRLWQGAPDFQSLADLNVWLEHRCKALWSELRHPELDQTVQEAFADEQGELMALPNAFDAFVEQTKRVTSTCLVHHEGNRYSVPASYANRAISLRIYADKLVMAAEGQHIAEHPRLFGSGHARRGHTQYDWHHYLSVLQKKPGALRNGAPFAELPPAFKKLQSILLQRPGGDRDMVEILALVLHHDEGAVLSAVELALECGKPSKEHVLNLLGRLTEEPPPKPIPIPKGLRLTLEPQANVNRYDSLRRAHDAA
What is the function of this protein?
Required for the transposition of the insertion element.
What are the official names of this protein?
Transposase for insertion sequences IS1326/IS1353.
What is the protein family that this protein belongs to?
Belongs to the transposase IS21/IS408/IS1162 family.
Protein: YDCO_ECOLI
Sequence: MRLFSIPPPTLLAGFLAVLIGYASSAAIIWQAAIVAGATTAQISGWMTALGLAMGVSTLTLTLWYRVPVLTAWSTPGAALLVTGLQGLTLNEAIGVFIVTNALIVLCGITGLFARLMRIIPHSLAAAMLAGILLRFGLQAFASLDGQFTLCGSMLLVWLATKAVAPRYAVIAAMIIGIVIVIAQGDVVTTDVVFKPVLPTYITPDFSFAHSLSVALPLFLVTMASQNAPGIAAMKAAGYSAPVSPLIVFTGLLALVFSPFGVYSVGIAAITAAICQSPEAHPDKDQRWLAAAVAGIFYLLAGLFGSAITGMMAALPVSWIQMLAGLALLSTIGGSLYQALHNERERDAAVVAFLVTASGLTLVGIGSAFWGLIAGGVCYVVLNLIADRNRY
What are the official names of this protein?
Inner membrane protein YdcO.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TTCA_LEGPA
Sequence: MSSNPSSVEKKLLHYTGKAIADFNMIQRGDRVMVCLSGGKDSFTLLTILNQLRIKSGNKFEIFAFTLDQAQPGWNDACLRQWLAEKSIPHEILTRDTYSIVKEKIPEGKTYCSLCSRLRRGIIYRYAEENGFNKIALGHHRDDLIRTLMMSILYNGDIRSMPPKLLSDNKKHIVIRPLCYVQEKDIITFASEQAFPIIPCNLCGSQENLMRKKVASLIDQLAIENPKVPSNMLHALQSLKPSQLMDQNFWNFKNLEDGLETAQSIQCEEVFNAQEFEIEDEKI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAT1_NEUCR
Sequence: MSNIISQAGQKAKEALTSAPSSKKVDDLKNEFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGFELDHCEDPVVYGRMVQRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKTINLSQTEFPPATPTIKSRRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVHESYGVVTLKKVKPESFTDAVKIAKGAAGFLGEFFYAIAQHRNWDRELDGLHSMIAY
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase-1.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Principally associated with the cell wall of conidia.
Protein: YCCT_SALTI
Sequence: MKTGALATFLALCLPVTVFATTLRLSNEVDLLVLDGKKVSSSLLRGAESIELENGPHQLVFRVEKTIRLPGNEERLYISPPLVISFDTQLISQVNFQLPRLENEREASHFNAAPRLALLDGDAMPIPVKLDILAITSTAKVVDYEIETERYNKSAKRASLPQFATMMADDSTLLSDVSELDTVPPQSQTLTEQRLKYWFRLADPQTRHHFLQWAEKQPPS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: ACLA3_ARATH
Sequence: MARKKIREYDSKRLLKEHLKRLANIDLQIRSAQVTESTDFTELTNQESWLSSTKLVVKPDMLFGKRGKSGLVALKLDLAEVADFVKARLGTEVEMEGCKAPITTFIVEPFVPHDQEYYLSIVSDRLGCTISFSECGGIEIEENWDKVKTIFLPAEKSMTLEVCAPLIATLPLEVRAKIGNFIMGAFAVFQDLDFSFMEMNPFTLVDGEPFPLDMRGELDDTAAFKNFNKWGDIEFPLPFGRVLSSTENFIHGLDEKTSASLKFTVLNPKGRIWTMVAGGGASVIYADTVGDLGYASELGNYAEYSGAPNEEEVLQYARVVIDCATTDPDGRKRALLIGGGIANFTDVAATFNGIIRALREKETRLKASRMHIYVRRGGPNYQTGLARMRALGEELGVPLEVYGPEATMTGICKRAIDCIMLPDA
What is the function of this protein?
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives.  May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids.  Required for normal growth and development and elongation of C18 fatty acids to C20 to C24 fatty acids in seeds.  In contrast to all known animal ACL enzymes having a homomeric structure, plant ACLs are composed of alpha and beta chains (By similarity).
What are the official names of this protein?
ATP-citrate synthase alpha chain protein 3, ATP-citrate synthase A-3, ATP-citrate lyase A-3, Citrate cleavage enzyme A-3.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TYSY_FRATN
Sequence: MREYLNFLKYIKENGVLKGDRTGTGTRSIFGYQMRFDLQKGFPLVTTKKIHIPSVVHELLWFLSGSTNIKYLNDNNVRIWNEWATVDGELGPIYGKQWRDFNGQGIDQIADVIQMLKTNPNSRRILVSAWNPCVVPSEKISPQENVVKGNSALPPCHAMFQFYVANNKLSCMLTQRSADAFLGVPFNIASYSLLTHMVAQQCNLDVGEFIWSGGDCHIYNNHIEQVNEQLSREPLALPTLKILRKPNSIFDYKYEDFEFENYNHHPAIKAKISV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTM1_NEOFI
Sequence: MNDGSDFDATATSSAAQRQVRVQLTSKQEDIALPDNAGPILVPTSLRRYALSTLVNNLLGNDKPIPFEFLINGTFLRTSIDEYLTANGISAETTLEIEYVRALIPPLHIASFQHDDWVSSTDVLSATSPAATWASATISQGQEKILSGSYDGLLRVWNMSSQIVATSPAAADGGHTASIKAAKFVTPNQIASAGLDRTVRLWKYSESDEGFSGTIAPQLELYGHKSGINSLAVHAPSNRILSASSDNSVGFWSTKKSDAPAAPEDLLPSAASRSSKRRKLNSSVTVPQRGPLALLSSHTAPVSAAIFDEKDSTVGYSASWDHSLRTWDLVTSTLVDTRTTSHSLLSLEHLPELSLLAAGTSARHITLIDPRASATTISAMTLRGHTNAVVSLARDPHSTYGLISGSHDGTCRIWDIRATKTDKDGVVGESVYSISRKSLEEQGKSDTKRVGGEGVKVFSVCWDKTVGIVSAGEDKRIQINRGEGVLSA
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ytm1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: HRPZ_PSESG
Sequence: MQSLSLNSSTLQSPSMALVLIRPETETTGPSTSSRALQEVIAQLAQELTHNGQLDESSPLGKLLGKAMAASGKAGGGLEDIKAALDTLIHEKLGDNFGASADNASDTGQHDLMTQVLNGLAKSMLNDLLTKQDDGTRFSEDDMPMLKKIAEFMDDNPAQFPKPDSGSWVNELKEDNFLDGDETAQFRSALDIIGQQLGSQQNAAGGLAGDSSGGGLGSPVSNTENSPGSLGDPLIDANTGPASNSNSNGDVGQLIGELIDRGLQSVLAGGGLGTPVSTANTALVPGGEQPNQDLGQLLGGLLQKGLEATLQDAGQTGTGVQSSTAQVALLLVNMLLQSTKNQAAA
What is the function of this protein?
Harpins are proteins able to elicit hypersensitive response (HR) in non-host plants and are required for pathogenicity in host plants.  HrpZ forms ion-conducting pores permeable for cations.  Such pore-forming activity may allow nutrient release and/or delivery of virulence factors during bacterial colonization of host plants (By similarity).
What are the official names of this protein?
Harpin HrpZ, Harpin-Psg, HrpZ-Psg protein.
What is the protein family that this protein belongs to?
Belongs to the harpin HrpZ family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Note=Secreted via type III secretion system (TTSS), delivered into the host intercellular space. HrpZ travels through the hrp pilus and it is secreted only from the pilus tip (By similarity).
Protein: ISDF_STAAE
Sequence: MMIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLEILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNRI
What is the function of this protein?
Part of the binding-protein-dependent transport system for heme-iron.  Responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Probable heme-iron transport system permease protein IsdF, Iron-regulated surface determinant protein F, Staphylococcal iron-regulated protein G.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TM252_MOUSE
Sequence: MQNRTGLILCALSLLTGFLMICLGGFFISNSIFHSQRNLVVAYVLLPMGFVILLSGIFWGTYRQANENKEMFNHVLRQHLAFQDLPLATVDRPDFYPPAYEESLDVEKQACPAGRELLGFPPPLYTETNLEFEHLEDPQPEAPPPYQEIIADAGAPAKAQDAEEPSRVLKAGTALQLTELTGR
What are the official names of this protein?
Transmembrane protein 252.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: U512C_DICDI
Sequence: MTIFNSISSISNPTRSTSSSIATLNYTGSVFNDNSTACFDNDLGRWGGCGGCGGSNVNIINLDIDIGRRRHRRCC
What are the official names of this protein?
UPF0512 protein C.
What is the protein family that this protein belongs to?
Belongs to the UPF0512 family.
Protein: CA16_CONPL
Sequence: MFTVFLLVVLVTTVVFSTSDHRPASNHENRRASKRISEMTWEECCTNPVCRQHYMHYC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).  Has possibly a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (lacks the Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Pu1.6.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAZ_RUEPO
Sequence: MARRFRGESNHKVDSKGRVSIPASFRRVLEAGDPNWQSGGNPELVIVYGDHRRKFLECYTMEAIDEVDAKIDALPRGSMERKMLQRMFHGQSFPTSVDETGRLVLPAKLRTKIALEDEAFFIAAGDTFQIWNPATYDQEELAAAEEWLDELPEDFDPMQYLDGAGGS
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RF2_CHLT2
Sequence: MHENFDKRLEVLLEGLALTRRSLDPEGKENELKELEQQAVQDGFWDDVARAGKISERIARLKQQLSEFNELKNKVSTIQFFLEDEESSKDLEMQKELEKEFVFCEKKITEWETLRLLSGELDRNSCFLSINAGAGGTESCDWVEMVLRMYMRWASSHSWRVEVIDRLDGEVAGIKHITLKLVGEYAYGYAKAESGVHRLVRISPFDSNAKRHTSFASVEVFPEIDDKIEVEIHPGDIRIDTYRSSGAGGQHVNVTDSAVRITHFPTGIVVSCQNERSQIQNREACMNMLRARIYQKLLQERLEKQNIDRKNKKEISWGSQIRNYVFQPYTLVKDVRTGYEVGNIQAMMDGELLDAFIKAYLVDYGEIT
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBT_HERA2
Sequence: MNIDDLSATIAELDSAAIQQAQQRQDQLTKPQGALGLLETLSIQLAGITQQCPPSVQKPIIVVAAADHGVAEYGVSAYPSSVTAQMVANFLAGGAAVSVLARHVGAELLIIDAGVQTAIVSEAANFRSEWLGAGTHNLAIEPAMSQAQAQSAFERGIRIAHELADAGHDLIALGEMGIGNTTAAACLTAIYCQQPAAAVTGHGTGVQAEHYQRKIEVVAQAVARVGSNVDGLQPLIEVGGFEIGILAGIIVGAAQRRVPILVDGFITTAAALVAQALAPKAIDYCIAAHCGAEPGHRIALQQLGLRPLLELDLRLGEGSGAALAIPLVQAACRILSEMATFASAHVDTAL
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: Y2211_STACT
Sequence: MTDLQNIEPQALRKLIRDKKVTGHTSGMAKGYIQANVVILPLDYAYDFLKFCFKNPKTCPLLDISEVGEVNFSKYGKDADITTDVGAYRVYENGELIETPTDVKHLFNDQMVSFLIGCSFTFEHALLEAGIPLRHLEEGHNVPMYITNIPAEPAGRFEGNITVSMRPMTMKDAIRATEITTHFKNVHGTPIHIGNPADFGIKDLENPDFGEPVKIKDNEVPVFWGCGVTPQSVALDAKPELIITHAPGHMFITDVKDSELSD
What are the official names of this protein?
Putative hydro-lyase Sca_2211.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.