PharMolix/UniProtQA huggingface dataset:
Protein: VATI_CHLMU
Sequence: MRINVDKYLFIGRKKSEFFSACRELGAVEFLAKNKLKDSENVRRISEGLKTLNLLTNKYSPSDLVLVKSGYLTTEQLLQEIFDLNHEITTITDSLKALSKEIFRVKPLGNFSSEEIRELTLKTGLSVRFFYKKHIEGAPLEVEEENVFYLATAYNYDYYVVIGVVSLSKDIFTEIEAPRSVGELREEEEHLQTLLRKKKARVCELYAYREELLEALCEQCNEQTLQHAEASTEDLFDDKVFSALGWVIVDRLTEVEKLCNSLGVYLERVQPDPDEVIPTYLENHGLGALGESLVNIYDTPASTDKDPSLWVFLSFFVFFSMIINDAGYGLIFLATSLFLSFKARKQVKHSLALKRFLKMFMILGGGCVCWGGATTSFFGVSVSYTSPFREYSLTHFLAMKKAEYYLKERPKGYKELVHDYPVLKDKKTPKEFLLAQGTSSGDSVYKAVVYDKFTDNILMEIALLVGVVHLSLGMLRYCRQRYSSIGWVVFMCGAYMYLPIYLQAVSLIHYALHVPYELGGQVGYYVTFIGLGIAVLGGIIQRGLRGLDEVTAVIQVFSDVLSYLRLYALSLAGAMVGNTVMVMSERFSPAVGVLIIIFGHTVNIALSIMGGVIHGLRLNFIEWYHYSFDGGGRLLHPLKRVICQKSQNI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit I, V-ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACKA_AZOPC
Sequence: MKILVLNCGSSSIKYKLFDMKAKSILAQGGVEKIGLTGSFLKLTLPNGKKVILEGEILEHRTGVEYILGVITSEKYGCIRSLSEIDAVGHRVVHGGEKFNSSVLIDDEVIRKITECIDLAPLHNPPNLNGIYAVVELMPSTPQVGVFDTAFHQTMPDFAYMYGLPYSLYEKYAIRRYGFHGTSHRYVSKRACEMLYMSYERQRIISCHIGNGASVTAIKNGISVDTSMGMTPVEGLLMGTRCGDIDAGILTYIMEKENIGTSAISTIINKCSGVLGTSGISSDMREIDDAIEIGNKKAILTSDIYTYKIKKYIGAYTVALEGIDILVFTGGVGENQFRIRQKICDGLEFIGIKIDEATNHIRGKETIISTTDSKVKVVVVPTDEEFMIALDTLSLLS
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_MARSD
Sequence: MFAKLEDIERSFMDLEQELADPEVYNNQERYRKVTMAHAELGDVVAAFREYKQLSADLEDNKEMAKDSDPEIREMAEMEIAEIKDRLPKLEEELKLLLLPKDPMDGKNIILEIRAGTGGEEAALFAADLFRMYSRFAESNGWKVEVMNSNPTGTGGFKEIIAAISGSRIYSMMKYESGTHRVQRVPATETQGRIHTSAATVAIMPEAEEVDVQVRNEDLRIDVFRASGPGGQSVNTTDSAIRITHLPTGLVVICQDEKSQHKNKAKAMKVLCSRLLQAEQDKQHAEMAEQRRAQVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDAVIEGDMQELVESLISHYQSEALKQQAQDG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSB_ECO27
Sequence: MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYLESLRNAPIKVYALNEDLIARGLTGQISNDIIPIDYTDFVRLTVKHSSQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y7538_DICDI
Sequence: MMTEFGSAMTLVTGLVAYGAYVKSKRQSNHYLLKTNNNFDVEKENFNYNNNNNNNNNNNNNNSNNNDNNNNNNSNSNNNNNNNNNNNNNNNNNINDKQINGTNIFDSNNQIKRRLFD
What are the official names of this protein?
Putative uncharacterized protein DDB_G0287599.
What are the subcellular locations of this protein?
Secreted.
Protein: OTC_DESPS
Sequence: MPDHLSSLGDFTGEEIASLIARAIELKEERSRGIRHQQLAGKSVALIFEKPSTRTRVSFESAMYGLGGQVLFLSGRDTQLSRSEPLKDMARVMSRYVDGIVVRTFGQEVVNELAQYATVPVINALTDLHHPCQILSDIMTVIEKKGAIQDLKIVWVGDGNNMANSWIQAAAKLGFELILACPEGYDPDAEILAAAQAEGAKPITLLRDPQTAVLGADVINVDVFASMGQESEQDERLKIFASYQVNAEMMAKAADDAIVLHCLPAHRGEEITEDVLEGPQCVAFDEAENKMHMHKAILERFLG
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUB4_GORGO
Sequence: MSFPKYKPSSLRTLPETLDPAEYNISPETRRAQAERLAIRAQLKREYLLQYNDPNRRGLIENPALLRWAYARTINVYPNFRPTPKNSLMGALCGFGPLIFIYYIIKTERDRKEKLIQEGKLDRTFHLSY
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4, Complex I-B15, CI-B15, NADH-ubiquinone oxidoreductase B15 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB4 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: RL14_CITK8
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRTEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SPEH_SACS2
Sequence: MMMGVELAFPKVVGKQVYGSLYECDEDVLKDTKRLEQIIKEAADIGNMNILDIKSWKIGEGVSVVAIILESHITIHTWPEYRFATVDVYSCGPHTSPLNAFRYIVEKLGAKRYTINEADRSSEF
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.  Has no arginine decarboxylase (ArgDC) activity.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: TRMD_PSE14
Sequence: MASLRIEVISLFPEMFSAISEYGITSRAVKQGLLQLTCWNPRDYTTDRHHTVDDRPFGGGPGMVMKIKPLEDALVQARQAAGDAAKVIYLSPQGRQLNQSAVRELAQEEAIILIAGRYEGIDERFIDAHVDEEWSIGDYVLSGGELPAMVLIDAVTRLLPGALGHVDSAEEDSFTDGLLDCPHYTRPEVYADQRVPDVLLSGNHAHIRRWRLQQSLGRTYERRADLLESRSLSGEEKKLLAEYIRERDDS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAM_HIRNI
Sequence: VDENAEDTHGLCGEKTCSPAQVCLNNECACTAIRCMIFCPNGFKVDENGCEYPCTCA
What is the function of this protein?
Inhibits mammalian elastases.
What are the official names of this protein?
Guamerin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I15 (antistasin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SRRM1_MOUSE
Sequence: MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASLKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKSPELPEPSVRMKDSSVQEATSTSDILKAPKPEPVPEPKEPSPEKNSKKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPGRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSSPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRMQMGKRWQSPVTKSSRRRRSPSPPPARRRRSPSPAPPPPPPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKTAMATQRNIRRVSKSPKADSLSRAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVTIATPATAAPAAVSAATTTSAQEEPAAAPEPRKETESEAEDDNLDDLERHLREKALRSMRKAQVSPQS
What is the function of this protein?
Part of pre- and post-splicing multiprotein mRNP complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).  Involved in numerous pre-mRNA processing events.  Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome.  Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex.  Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions.  Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.
What are the official names of this protein?
Serine/arginine repetitive matrix protein 1, Plenty-of-prolines 101.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus matrix. Nucleus speckle.
Protein: PYRF_BACMK
Sequence: MSQSLIVALDFPGKQEVEQFLHHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKSAMRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSETMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVCSTLEVPKLREVCGNEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQWEGVTV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: SSUB_SHISS
Sequence: MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVGRSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVGLGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRLEMQDLIVSLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVDIPRPRRLGSVRLAELEAEVLQRVMRRGHSEQLIRRHG
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FABG_YEAST
Sequence: MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET
What is the function of this protein?
Involved in biosynthesis of fatty acids in mitochondria.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase, 3-ketoacyl-acyl carrier protein reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ASNS_MIMIV
Sequence: MCGIICFIQYGGQKIDLVSCLNCLDKLNNRGPDAQSYQVIELGDITIFLGFTRLAIMDTSEAGLQPFKDNNSNYSICNGEIYNYKNLAEKFNIEMQSQCDCEILLPLFNLRGFEGLLSDLDAEFATVIVDKYNSKLYAARDKYGVRPLYYGYNCEKGLIGFASELKALHSVMEYVEQVKPNQYVTIDLSFRPSIPFDLQNFVKLFQFTNYHEYYQSHKSLIDYHEPNIEQLQTSINHLLTEAVRKRLYADRQIGFLLSGGLDSSLIVAIATRLLGPTNIVCFSVGFEGSPDVAAAREVVKFLGIKNHHIVPFSVDIGLNAINDVIKTIETYDITTIRASTPQFIMAKYIQENTDIRVLLSGEGSDEIHGSYKYMRSAPNSQEFHKETIRLLEELYLFDNKRTDRTMAGNGLEVRVPFLDFNYVDFIMNIDPNLLMYKSDYIEKKIIRDAFKGYLPENILYRPKEAFSDAVSSKEINWYRSIQKITEEIYTDEKLQNSNYKFNKPEIKEALYYRDIFNSHYGGRDHIIPHYWLPRFQQNNVLDPSATILPI
What are the official names of this protein?
Probable asparagine synthetase [glutamine-hydrolyzing], Glutamine-dependent asparagine synthetase.
Protein: CAAT1_ARATH
Sequence: MASGGGDDGLRRRGCSCTKDDFLPEESFQSMGNYLKALKETPSRFMDRIMTRSLDSDEINEMKARSGHEMKKTLTWWDLMWFGIGAVIGSGIFVLTGLEARNHSGPAVVLSYVVSGVSAMLSVFCYTEFAVEIPVAGGSFAYLRVELGDFMAFIAAGNIILEYVVGGAAVARSWTSYFATLLNHKPEDFRIIVHKLGEDYSHLDPIAVGVCAIICVLAVVGTKGSSRFNYIASIIHMVVILFVIIAGFTKADVKNYSDFTPYGVRGVFKSAAVLFFAYIGFDAVSTMAEETKNPGRDIPIGLVGSMVVTTVCYCLMAVTLCLMQPYQQIDPDAPFSVAFSAVGWDWAKYIVAFGALKGMTTVLLVGAIGQARYMTHIARAHMMPPWLAQVNAKTGTPINATVVMLAATALIAFFTKLKILADLLSVSTLFIFMFVAVALLVRRYYVTGETSTRDRNKFLVFLGLILASSTATAVYWALEEEGWIGYCITVPIWFLSTVAMKFLVPQARAPKIWGVPLVPWLPSASIAINIFLLGSIDTKSFVRFAIWTGILLIYYVLFGLHATYDTAKATLKEKQALQKAEEGGVVADNSCSAT
What is the function of this protein?
High-affinity permease involved in the transport of the cationic amino acids (e. g.  arginine, lysine, histidine, citrulline, valine, and glutamate).  Transport mostly basic amino acids, and, to a lower extent neutral and acidic amino acids.  May function as a proton symporter.
What are the official names of this protein?
Cationic amino acid transporter 1, Amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HIS4_LISMC
Sequence: MQIFPAIDLKNGQCVRLFQGDFSKKTVVNEDPIAQAKAFATDGATYLHIVDLDGALEGRPINLEIIQRMKKAAKIPVQVGGGIRSMAQVDYYLESGIDRVIIGSAALTDPDFLRAAVQKYGAKIVAGIDAKNGFVATRGWLDVSQVSYLDLAKRMEKVGVETIIYTDISRDGTLTGPNLEQMANLKEHVKVSLIASGGVSSRADLEALAQLGLYGAIAGKALYNHDISMSDIVEVEQIAY
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_ARTS2
Sequence: MSRLFGTDGVRGLANGLLTAELAMQLAQAAAVVLGHERSTNGARPRAVVARDPRASGEFISAAVSAGLSSSGIDVYDAGVLPTPAAAYLVADLHADFGVMISASHNPAPDNGIKFFAKGGQKLPDEVEDAIEAQMAKDPVRPTGSDVGRIQTFSDAEDRYIVHLLGTLPHRLDGLKVVLDCAHGAASGCSPQLFNDAGAEIVVIGAEPDGLNINDGVGSTHLGALQRAVVEHGADLGIAHDGDADRCLAIDHEGNEVDGDQIMAILALALKESGKLKDNVLVATVMSNLGLKIALRNAGISIRETAVGDRYVLEEMRDGGYNLGGEQSGHVIFADHATTGDGLLTGLQLAAQVALTGKSLKELATVMTKLPQLMINVKKVDKARAGTDEGVLAAVAEASAELGETGRVLLRPSGTEALVRVMVEAADMPTAERICKHLAAVVEERLAVAPAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: HRCA_STRAW
Sequence: MLSERRLEVLRAIVQDYVGTEEPVGSKALTERHNLGVSPATVRNDMAALEDEGYIAQPHTSAGRIPTDRGYRLFVDKLAGVKPMTGPERRAIQNFLDGAVDLDDVVGRTVRLLAQLTRQVAVVQYPSLTRSTVRHVELLSLAPARVMLVLITDTGRVEQRMIDCPAPFGETSLADLRARLNSRVAGRRFADVPQLVQDLSEAFDPEDRGTVTTVLSTLLETLVEETEERLMIGGTANLTRFGHDFPLTIRPVLEALEEQVVLLKLLGSAGDSGMTVRIGHENAYEGLNSTSVVSVGYGSGDEAVAKLGVVGPTRMDYPGTMGAVRAVARYVGQILAES
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RPOB_GEOMG
Sequence: MAYSIANNQLLRQNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSVFPIKDFSDTASLEYVSYSLGTPKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSIRDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPGVFYDHDKGKTHSSGKVLYSARVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGNSAEELLNFYYRSEEIGLDGERMWKKADAELLTTQKTSSDIVDSKTGEVIIKANRKFTKAAIRKMTEHGITEIPIKAEEVCGKYASTDIVDPATGEVLVECNEEISQAKLDEIKARGISEFKVLFIDNLHVTSSLRDTLLVDKINTTDDALIEIYRRLRPGDPPTLKSAQALFDNLFFNAERYDLSAVGRLKLNYKLGLGVPLDCQVLTKEDILEVVRYLIDLKNGRGTIDDIDHLGNRRVRAVGELLENQYRIGLVRMERAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYRIVSEGKVTAEVKFFSALEEEGHAIAQANAEMDADGRFVNDYVSARKSGEFLLVHRDELELMDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDSGVSVVARHTGVVESVDASRIVVKIDEDEYDETGTGVDIYNLIKFARSNQNTCINQRPVVKVGDHVKRGDVIADGPSTDMGELALGQNVVVAFMPWGGYNFEDSILISEKLTKDDRYTSIHIEEFECVARDTKLGKEEITSDIPNLGEETLKDLDESGIIRIGAEVKPGDIMVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKVFSRKGNDKDSRTEMIERMEEEKLRKDEQDEIRIIRDSAVGKLKRLLVGKTAAVKVEDKNGKTVIAKDAAITEEALTAIPLDRWDEISVSGGEGVEEKVAAILATLQQQIDIIKYVFDDKVQKLKRGDDLPPGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGVPSRMNVGQILETHLGWAAKGIGWKIEEMLEKHSPSATIKEYLQKVYGSKEMNAFLDSLNEEELINVAKRLQRGVPMASPVFEGASEEQIRSMLDKAGFDETAQVRLFDGKTGEPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKSDDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEGDED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ENGB_CYTH3
Sequence: MKMNAKFISSYDDYQKCPEITKPEYAFIGRSNVGKSSLINSLTGVKNLAMTSSKPGKTQLINLFTIEETWILADLPGYGFAKASQSSRIKWGRMVHDYLKNRTNLTTVFLLVDSRHEPMKSDLEQITWLASNGIPFSLIFTKIDKQSLTQTNKILASWTKVLSENWEELPKMFLTSSESGKGTEELLTYIDEINKQIAN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: GTR7_MOUSE
Sequence: MEDKEIGTPLPLPHSEARLQPTLVLTTLSAAFGSVFQYGYNIAVINTPHKVFKSFYNDTHFERHGTFMDESTLLLLWSCTVSMFPLGGLLGSLVVGLMVNKWGRKGTLLINNVFAITSAVLMGVSKVARAFELIILSRVLVGICAGIAYSTLPMYLGELAPQNLRGALGTMTEVFVIIGVLLAQIFSLQAILGNATGWPILLALTGVPAVIQLLSLPFFPESPRYTLIEKGDEETARQALRRLRGQNYNVEAEMEEMRTEERTEQAEGRLSVLNLFTFRPLRWQLISIVVLMAGQQLSGINAVNYYADVIYTSAGVDPTQSQYVTLGSGVINLVMTLVSAVIIERLGRRILLLSGYAICCSACLVLTVALLLQSTAPELSYLSIVCVFSYIVGHSIGPSPVPSVVRTEIVLQSSRTAAFTVDGAVHWLTNFIVGLTFPSIQVAIGAYSFLVFAGVCILTAAYIYVVIPETKGRTFVEINCAFAKRNGVEFPEEKEVATAKPHTPSLPTKETAF
What is the function of this protein?
Probable sugar transporter.  Even if its physiological substrate is subject to discussion, it is able to transport glucose and fructose.  Does not transport galactose, 2-deoxy-d-glucose and xylose.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 7, Glucose transporter type 7, GLUT-7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Protein: W11B2_XENTR
Sequence: MALIRHCVTLLLILCCSRLCGAIQWLGLTVNGSRVAWNESEHCRLLDGLVPEQSQLCKRNLELMQSVVNAAKQAKLTCQMTFSDMRWNCSSVENAPNFTPDLSKGTRESAFVYALASATISHTIARACASGELPTCSCGATPAEVPGTGFRWGGCGDNLHYGLNMGSAFVDAPMKSSKSGGTQATKMINLHNNAVGRQVLMDSLETKCKCHGVSGSCSVKTCWKGLQDLPHIANELKSKYLGATKVIHRQTGTRRQLVPRELDIRPVRESELVYLVSSPDYCAKNPKLGSYGTQDRVCNKTSVGSDSCNLMCCGRGYNAYTETIVERCQCKYYWCCYVMCKKCERTVERYVCK
What is the function of this protein?
Ligand for the frizzled7 transmembrane receptor.  Primarily acts via non-canonical Wnt pathways mediated by either Ca(2+) and PKC, or by JNK and dvl2/dsh.  Depending on the cellular context, can also signal via the canonical Wnt pathway mediated by beta-catenin and dvl2/dsh.  May also inhibit canonical Wnt signaling.  Maternally initiates dorsal/ventral axis formation by a canonical route, which signals via lrp6.  In a complex with wnt5a, activates the canonical and non-canonical processes involved in axis formation.  In the non-canonical pathway, acts through fzd7/fz7 to induce phosphorylation of dvl2/dsh.  Signals through a non-canonical Wnt pathway to regulate convergent extension movements during gastrulation.  Interactions with the secreted Wnt antagonist sfrp5 to coordinate foregut development, acting via a non-canonical wnt pathway whereby sfrp5 restricts wnt11b activity to prevent inappropriate foregut formation.  Mediates cardiogenesis via non-canonical Wnt signaling involving JNK-activation and PKC.  Acts redundantly with wnt11/wnt11r during pronephros induction (By similarity).
What are the official names of this protein?
Protein Wnt-11b-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: SEPC_PSEP1
Sequence: MKTHYLSIALSVALSGCSLIPDYQRPPAPIQAGWPQGEAYAKLKAGTHRPSQTRDAELNWQVFFRDPVMRELIATALNNNRDLRQTALNVEAYRALHRIERSALLPRANTGVGATRQRLPADLSPTGEAGIQSQYDTTLSMSYELDMFGRLRSLERAALQEYLAAAETQRSMQIALIADVAIAYLSWRSDQAQLDLARSTLASYENSLNLIKSSREVGTASALDVRQARSLVETARVQQTLYTRQVAQDMNALQLLLGTKLPADLPISDVLDQPLAALSTGLPADLLLHRPDIRAAEHRLLAANANIGAARAAFFPSITLTAAAGTASHELDGLFEGGSGLWAFMPRINLPIFTAGRLRGNLDYRNVIKDINVAEYEKSIQTAFREVADGLAARGTFGEQLQAQRDLVDNNQAYYKLAYQRYDEGVDNYLAVLDAQRELFAAQQQFLSDRLNQLSSEVRLFKALGGGWDNISSQPLTAQN
What is the function of this protein?
Probable outer membrane component of the SepABC efflux pump with unknown specificity.
What are the official names of this protein?
Probable efflux pump outer membrane protein SepC.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: NUOH_BUCBP
Sequence: MIFLPISSIETKTYIFQSIVILVCVLITASIMSVVERRVLGLLQNRYGPNRVGWQGTLQVVADMIKLFFKEDWIPTFSKKITFLIAPILAFISLLLVITIIPLSPSIVIVNLDIGVLFFLMMASLSVYSVLLAGWSSNNKYALLGSIRATAQTLSYEVFLGLSCMGVVARAKSFNMIDIVDSQIGLWNIIPQFFGFLAFFIAGLALCHRHPFDQPESEQELADGYHIEYSSIKFGLFFIGEYISIIVVSSLISTMFFGGWLGPLFPSYFWFILKTLCFMMIFILIRASLPRPRYDKMMLFGWKVCFPLTLINLIFTALIMLY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPF_YERPG
Sequence: MNLNATILGQAIAFVLFVIFCMKYVWPPIMAAIEKRQQEIADGLSSAERAKKDLDLAQANATDQLKKAKAEAQVIIEQASKRKAQILDEAKAEAEQERNKIVAQAQAEIDAERKRAREELRKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.