PharMolix/UniProtQA huggingface dataset:
Protein: RPOZ_ANAPZ
Sequence: MDSEESRCFSGYDGNRFKLVILASQRAHELSSGAATLVDRQGDKNTVVALREIASNQLDLSTVFGLAVQRCRKYLEEFAGSRGIAGHSSHVSPSRSSRHTGLGKSFVDNKSTYSASFLDQDKFLSGGKDDGIEGF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL22_HAEIN
Sequence: METIAKHRYARTSAQKARLVADLIRGKKVAQALEILTFTNKKAAALVKKVLESAIANAEHNDGADIDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RS15_RICBR
Sequence: MSITQERKQELIKNYAINDNDTGSSAVQCAILTERINNLTEHFKSNHKDHTSRRGLLILVGRRRRLLNYIKKKNVSEYLDLISKLGIRKIK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: LEU3_CAMJR
Sequence: MKAYKVAVLAGDGIGPLVMKEALKILTFISQKYNFSFEFNEAKIGGASIDAYGVALSDETLKLCEQSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLTHASPLKNEIIQKGVDILCVRELTGGIYFGKQDLGKESAYDTEIYTKKEIERIAHIAFESARIRKKKVHLIDKANVLASSILWREVVANVVKDYQDINLEYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNIANPIAQILSAALMLKYSFKEEQAAQDIENAISLALAQGKMTKDLNAKSYLNTDEMGDCILEILKENNNG
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_RAT
Sequence: MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: YAAI_SALA4
Sequence: MRSVLTISAGLLFGLALSSVAHANDHKILGVIAMPRNETNDLALKIPVCRIVKRIQLTADHGDIELSGASVYFKTARSASQSLNVPSSIKEGQTTGWININSDNDNKRCVSKITFSGHTVNSSDMARLKVIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: LEA2_PHAVU
Sequence: MASSNLLTLALFLVLLTHANSASDTSFNFYSFNETNLILQGDATVSSKGYLQLHTVDSMCSAFYSAPIQIRDSTTGNVASFDTNFTMNITTQREANSVIGLDFALVPVQPKSKGHTVTVQFDTFRSRISIDVNNNDIKSVPWDEQDYDGQNAKVRITYNSSTKVLAVSLSNPSTGKSNEVSARMEVEKELDDWVRVGFSAISGVHEYSFETRDVLSWSFSSKFSQHTTSERSNILLNNIL
What is the function of this protein?
Lectin and alpha-amylase inhibitor.  Acts as a defensive protein against insects.
What are the official names of this protein?
Alpha-amylase inhibitor 2, Alpha-AI-2, Alpha-AI2, Lectin.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: VOLA_VIBCH
Sequence: MKQVIKLSLLCSALWLAGCGDETNSSGASTEVVYESYIQQALQRDTTIKFALSGKDANVPLPSFALMNAKDGTLEIPPGSNTSGSNPLVAMGQVDGWPITMPLFLDFKGAGLADNIITSGIYLYELTDSMTGSPSIKALLTNGVDYTAVSSAASDKILIMPTKALNASSEYILAVTSEVSDANGNPVGTSASYAALKSKNKIYSEGDIATLQKVTQGVEKIFQLSGVDETQIVYSTWFSTQSVSNTLFATRGATASAFASGSNQLETVWKQTGLGLDTAYTIQLGTPVDFAAALTADDNFSTYVGADKKTAILGTYTANTVDVTKGTVRLPYYLETGSNWNTQPFESAMPSLAKIKAALADSKEQLTIGSQLLAAGIDTTKLATDASEQLKLMGLTLTKSDGTALDPERYITRYSPVPKVKSVQDVPFLLFTPAGAAPTDIVIYQHGVTTAKENAYAFAKNLTAVGLAVIAIDLPLHGERSLDSTRSANSDPLAYINLTYLAVARDNLRQSILDVLGLRAALTLSQPLFTGTRLSGINVGTGSKVRMLGHSLGGIVGTSAIAESNKTLGSTAADAMYSFSGAAIQNSGGQISNLLLGSAFFGPKIKHNVALSASTEYKGFADAQCASLDDSACYNLFTSLATQEQLAQVTSGFQMFSYAAQTLLDTIDPYSVVSTKLNNGGLTTPLYFSEVDGDSVVPNKVSNPTGSLVYLSPQFAGTEPLATLLGLTTVNAGQTAPNATKSFVQFNSTAKHSTFVAPQDAGYADLAHHTEMQTETADFLADDSLGAVSNSNSVLK
What is the function of this protein?
Required for the utilization of the prevalent host lipid lysophosphatidylcholine (LPC).  Functions as a lipase that cleaves exogenous LPC and generates free fatty acids, which are then transported into the cell by fatty acid transporters such as FadL, and used in various metabolic pathways.
What are the official names of this protein?
Lysophospholipase VolA, Vibrio outer membrane lysophospholipase A.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Note=Surface-exposed.
Protein: STAT1_PIG
Sequence: MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLENQDWEHAANDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIICNCLKEERKILENAQRFNQTQSGNIQSTVMLDKHKELDSKVRNVKDKVMCIEHEIKTLEDLQDEYDFKCKTLQNREHDTNGVAKNDQKQEQMLLQKMYLMLDNKRKEVVHKIIELLNVTELTQKALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQALWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQKLNYNLKVKVLFDKDVSERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGARTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLNPPCARWSQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPTAGPDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLSLWNDGCIVGFISKERERALLKDQQPGTFLLRFSESCREGAITFTWVERSQNGGEPYFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEVHPSRLQTTDNLLPMSPEEFDEVSRMVGPVEFDVTWNKFSGTMNLD
What is the function of this protein?
Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors.  Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2.  The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus.  ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state.  In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated.  It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state.  Becomes activated in response to KITLG/SCF and KIT signaling.  May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
What are the official names of this protein?
Signal transducer and activator of transcription 1.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to IFN-gamma and signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Monomethylation at Lys-525 is required for phosphorylation at Tyr-701 and translocation into the nucleus. Translocates into the nucleus in response to interferon-beta stimulation.
Protein: BR2A_ODOIS
Sequence: MFNMKKSLLLLFFLGTISLSLCEEERDADEDDGVEMTEEEVKRSLLDTFKNLAVNAAKSAGVSVLNALSCKISRTC
What is the function of this protein?
Has antimicrobial activity against Gram-negative bacterium E. coli ATCC 8739 (MIC=50 ug), against Gram positive bacteria S. aureus ATCC 6538 (MIC=12. 5 ug), methicillin-resistant S. aureus ATCC 43300 (MIC=100 ug) and B. subtilis ATCC 6633 (MIC=12. 5 ug).  Has no activity against fungus C. albicans ATCC 90028.
What are the official names of this protein?
Brevinin-2ISa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: RL1_PROM5
Sequence: MKKLSKRMTALSTKIEDRTYAPLEALAIIKENANAKFDETIEAHIRLGIDPKYTDQQLRTTVALPHGTGQSIKIAVITSGENVAKAKSAGADLFGEEDLVESINKGNMDFDLLIATPDMMPKVAKLGRVLGPRGLMPNPKAGTVTSDIASAIKEFKAGKLEFRADKAGIVHVRFGKASFTENALFENLKTLQESIDKNKPSGAKGKYWKTFYVTSTMGPSVQVDINALQDYQPES
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ISPD_PARPJ
Sequence: MTSRLFALIPCAGTGSRSGAAMPKQYRTVAGRDMLHYSLAAFDACSEFAQTLVVIAPDDAHFDGRRFGGLRFAVRRSGGASRQASVLNGLHALAEFGARDDDWVLVHDAARPGITPALIRTLIGALKDDPVGGIMALPVADTLKRIDATSSDGRIARTEARDGLWQAQTPQMFRIGMLREAILRAQADGHDLTDEASAIEWLGHAPKLVQGSLRNFKVTYPEDFDLAEAILSRPAAAS
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: SYE_MESH7
Sequence: MKIRTRYAPSPTGFLHIGGARTALFNYLFAKHHNGDFILRIEDSDNSRNIKDGEKSQIENLLWLGIIPDEKPGSETKFGPYRQSEKLERYQKLAQELIKKGFAYYAFDNQEELELQKKEQIAKGIFSFRYDQNWLKISDQEKQKRLKNKHFVIRFKVDKAKNFCWNDLVRGQICFEGSAISDWVIIKSDGFPTYNFAVVVDDFDMEISHIFRGEEHISNTPKQIGIYQAFNWKTPKFGHLTIITDKNGKKLSKRDKNLFQFIEDYKNQGYHSEAFFNFLALLGWTSPDSQEFFDHKSLIKAFDYKRLSKAPSYFDIEKLNWFSKSYISKMTVDKILENLELSDNQIWNRFFVETFQKSSIKYADFYKNFEFFHRPKQEMDEKMLEIFEKLDKKPVKIFASRIDYQNWDYTKINDLIKEIGQKLEITGKNLLLPIRLATTFTNSGPELARAIWLLGKKIIEKRLLKWK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4WP_SINFN
Sequence: MSRTAEKPFETVENSIVGQSTAINRGEQLTHAIELQELAGSVFKSTMMVGFELSLNTFAAVQANTFANLHHLSEFLGAKSPSQVFDLQCSFLRKRIDMGVEQVKESQALSTKALIDMSKPIKEFFEKAIADLKTA
What are the official names of this protein?
Uncharacterized protein y4wP.
Protein: RL29_ENT38
Sequence: MKANELREKSVEELNAELLNLLREQFNLRMQAASGQLQQTHLLKQVRRNVARVKTLLTQKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: TOLB_SALCH
Sequence: MKQALRVAFGFLMLWAAVLHAEVRIEITQGVDSARPIGVVPFKWAGPGAAPEDIGGIVAADLRNSGKFNPLDRSRLPQQPATAQEVQPTAWSALGIDAVVVGQVTPNPDGSYNIAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGSVRQVASFPRHNGAPAFSPDGTKLAFALSKTGSLNLYVMDLASGQIRQITDGRSNNTEPTWFPDSQTLAFTSDQAGRPQVYKMNINGGAAQRITWEGSQNQDADVSSDGKFMVMVSSNNGQQHIAKQDLVTGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKSPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FABZ_STRZJ
Sequence: MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFFNGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQLVMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM2_CANLF
Sequence: MCNTNMSVSTGGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQHEPSDSGTSVSENSCHREGGSDQKDPVQELQEEKPSSSDLISRPSTSSRRRTISETEEHADDLPGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYRVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPPHCNRCWALRENWLPEDKGKIPEKATPENSTQVEEGFDVPDCKKAAASDSRESCAEEIDDKITQASHSQESEDYSQPSTSNSIIYSSQEDVKEFEREETQDKEEIVESSFPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.  Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.  Also acts as a ubiquitin ligase E3 toward itself and ARRB1.  Permits the nuclear export of p53/TP53.  Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein.  Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation.  Component of the TRIM28/KAP1-MDM2-p53/TP53 complex involved in stabilizing p53/TP53.  Also a component of the TRIM28/KAP1-ERBB4-MDM2 complex which links growth factor and DNA damage response pathways.  Mediates ubiquitination and subsequent proteasome degradation of DYRK2 in nucleus.  Ubiquitinates IGF1R and SNAI1 and promotes them to proteasomal degradation.  Ubiquitinates DCX, leading to DCX degradation and reduction of the dendritic spine density of olfactory bulb granule cells.  Ubiquitinates DLG4, leading to proteasomal degradation of DLG4 which is required for AMPA receptor endocytosis (By similarity).  Negatively regulates NDUFS1, leading to decreased mitochondrial respiration, marked oxidative stress, and commitment to the mitochondrial pathway of apoptosis (By similarity).  Binds NDUFS1 leading to its cytosolic retention rather than mitochondrial localization resulting in decreased supercomplex assembly (interactions between complex I and complex III), decreased complex I activity, ROS production, and apoptosis (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase Mdm2, Double minute 2 protein, Cdm2, RING-type E3 ubiquitin transferase Mdm2, p53-binding protein Mdm2.
What is the protein family that this protein belongs to?
Belongs to the MDM2/MDM4 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Nucleus, nucleolus. Nucleus. Note=Expressed predominantly in the nucleoplasm. Interaction with ARF(P14) results in the localization of both proteins to the nucleolus. The nucleolar localization signals in both ARF(P14) and MDM2 may be necessary to allow efficient nucleolar localization of both proteins. Colocalizes with RASSF1 isoform A in the nucleus (By similarity).
Protein: DA2L_ARATH
Sequence: MGNKLGRKRQIVDERYTKPQQGLYMSKDVDIKKLKKLILESKLAPCYPGLEETPSSHHDLEECPICFLYYPSLNRSRCCMKSICTECFLRMKSPNSAQPTQCPFCKTSNYAVEYRGGKTKEEKSFEQIEEQRVIEAKIRMRQKEVEDDEERMQKRLESYSSSSSTSAATLDTEYGSAAEDDEEIVSSQESCLPSHHPQVTRDGQFDFDLEDIMVMEAIWLSMQEPGIQRNTSPDDISEKDRNEEPSTPSSSSPSGGLACAIAVLAERQQMVGVSSSNQNVNLASQNLVPDNGNNSHYNAIEQDSNHYLQGAGISYTRSDMTDDSGGETSREVTWQ
What is the function of this protein?
E3 ubiquitin-protein ligase involved in the regulation of organ and seed size.  Probably functions to restrict cell proliferation during organ and seed development.
What are the official names of this protein?
E3 ubiquitin-protein ligase DA2L, Protein DA2-like, RING-type E3 ubiquitin transferase DA2L.
Protein: CATNT_THET2
Sequence: MAHMDFPFYTPKDAFPVGGAVRDLLLGRRPTDLDYAALDPEKAAEEAKRRLGGSLFPLDPKRGHYRLVVGERTLDFTPLEGRLEEDLLRRDYRVNALLWKGGAVFGLKGVEEDLRRRLLVPVREENLYQDHLRSLRGVRLAATLGFGLPRRTREALGRHARFLQAHPEALPARERVKEELARLLLSPRAAFGLRLLERVGLLGVYLPELALLVGLHQGGVHHLPAWEHTLSAVFHLLWLWPEAPLEARLAALFHDVGKPLTRRFDPEVGRFRFLGHAEVGAEIARASLFWLRFPKEVVERVAGLVRRHMDRLPEERKALRRFFLRRQDLLPDLVYLMAADRLATRGVEREAWEVLGRYEEVLKDPLPQRPLLSGEEVMALLGLQEGPEVGRALKALLEAQAEGRVGTKEEARAFLLYWRGGREAQASGTPDHPH
What is the function of this protein?
tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus.  Adds the two cytidine residues to tRNA.
What are the official names of this protein?
CC-adding tRNA nucleotidyltransferase, C-adding TNT, CC-adding enzyme.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
Protein: HIS2_CUPPJ
Sequence: MTESHSAGTDVLARLAVVLESRKPENGGDPEKSYVARLFRKGDDAILKKIGEEATETVMAAKDARAAGKTGADADKIVYEVADLWFHTMVLLANFGLTPADVVNELARREGLSGIEEKASRKDQG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_WOLSU
Sequence: MARKIPLNRIRNIGIAAHIDAGKTTTTERILFYTGVSHKVGEVHDGAATMDWMEQEKERGITITSAATTCFWKDYQVNIIDTPGHVDFTIEVERSMRVLDGAVAVFCSVGGVQPQSETVWRQANKYGVPRMVFVNKMDRIGANFYNVESQISDRLKARPVPVVIPVGAEDTFKGVIDLLQMKALIWNDETMGAKYDIEEIPADLVEKANEYREKMIEAAAEQDEALMEKYLNGEELTTEEIKRGLKIGCHAMAIIPMLCGSSFKNKGVQTLLDAVIDYLPAPTEVADIHGVDAKDETKEISVQSSDEGEFAGLAFKIMTDPFVGQLTFVRVYRGSLESGSYVYNSTKGKKERVGRLLKMHANKREDIKEIYAGEICAFVGLKETLTGDTLCSEKEPVILERMEFPEPVISIAVEPKTKADQEKMGIALNKLAEEDPSFRVNSDEETGQTIISGMGELHLEIIVDRMKREFKVEAEVGQPQVAFRETVRKAVNKECKYAKQSGGRGQYGHVFIKLEPQEAGKGYEFVNDISGGVIPKEYIPAVDKGIKEAMQSGVLAGYPVVDFKVTLYDGSYHDVDSSEMAFKIAGSMAFKDAAREASPVLLEPIMKVEVEVPEDYMGDVIGDLNRRRGQINSMGDRSGIKVINAFVPLAEMFGYSTDLRSATQGRGTYTMEFSHYGEVPGNISKEIIEKRKG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PME31_ARATH
Sequence: MATTRMVRVSQDGSGDYCSVQDAIDSVPLGNTCRTVIRLSPGIYRQPVYVPKRKNFITFAGISPEITVLTWNNTASKIEHHQASRVIGTGTFGCGSVIVEGEDFIAENITFENSAPEGSGQAVAIRVTADRCAFYNCRFLGWQDTLYLHHGKQYLKDCYIEGSVDFIFGNSTALLEHCHIHCKSQGFITAQSRKSSQESTGYVFLRCVITGNGQSGYMYLGRPWGPFGRVVLAYTYMDACIRNVGWHNWGNAENERSACFYEYRCFGPGSCSSERVPWSRELMDDEAGHFVHHSFVDPEQDRPWLCLRMGVKTPYSA
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin (PubMed:18936961).  Acts in a blockwise manner, resulting in a cell wall rigidification.
What are the official names of this protein?
Pectinesterase 31, PE 31, Pectin methylesterase 31, AtPME31.
What is the protein family that this protein belongs to?
Belongs to the pectinesterase family.
Protein: MURD_CORDI
Sequence: MTVSVEELKVLLPELAGRVLVAGAGVSGVGITQLLREMGCAVTVADSNSAQLDKLAQQTGCQTISPADVVSDGFQDYTVVVTSPGWRPDSPLLVAAQSAGLEVIGDVELVYRLDRAEVFGPKRTWMVVTGTNGKTTTTAMLAEIMQHSGARAAAVGNIGVSVADAVRTQPRIDVLVAELSSFQLHWSSTLVPDVGILLNLADDHIDWHGSFAQYAQDKAKVLAAPTAIAGFDNGHVMTETTRIQRAEDADPIIGFTLGEPAKGMVGVRDGQLIDCAFGDNVVLRSAEGIEPAGPAGLNDALAAAAAARSMGVSAVCIEEALSKFEVAGHRGQCVGRHREVVAIDNSKATNPHAADSALAGFSSVVWVAGGQLKGAEIDELIVRHAGRIKAVALLGVDRDVIEDSVRTHIPGIPVLSVSETDPRRAMDEAVAWSVSQAEAGDAIVLAPAAASLDMYTGMGQRGDMFATAIAQHLHD
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_CAMFF
Sequence: MVKKHRETKETDISVELEIYGSGKCEIDTGVGFFDHMLNALCKHSLMDIKLVCKGDLFIDDHHSVEDCGIVLGSAIKESIYPLSCVERYGNSIVVMDEAAVECAIDLSNRPYLVYESSLNEKIGTFDSELIREFFQALAMNAGITLHLIRLRGDNSHHIAEATFKAFAVAFRRAISKNDRMGTPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_BACMK
Sequence: MRNIQIALTKGRLEKHVIPLFEKIGIGCSELKDKGRKLVFKSKNTNISFILVKAVDVATYVEHGVADIGVVGKDILMEFEKDIYEMVDLGVGVCKFCVASIPTYNPKSYRKKRIATKYPHITSTYFHDKGEDVEIIKIEGSVEIAPLLGLADAIVDIVETGKTLQENGLIVFEEMCSISARMIVNKAALKTKKDEIFRIINMMEQEILSGK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO_MYCBT
Sequence: MSDLARTDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAAESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKAVRVNEQFQVTRQFWAYAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTEFIESPDEFARRLPFMAAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCVQNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFVGAGGDTLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAPPLGALHLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLSVLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQRVQVIRRDERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQKCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEVWSWSTKALKLGAA
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.