PharMolix/UniProtQA huggingface dataset:
Protein: RNH3_BACAN
Sequence: MSNSIVIQTNSTVIEDMKQQYKHSLSPKTPQGGIFMAKVPSCTITAYKSGKVMFQGGRAEAEAARWQTVPQTPKIAVKKSVDSHRYAPPASIGTMSIVGSDEVGTGDFFGPMTVVAVYVDAKQIPLLKELGVKDSKNLNDEQITAIAKQLLHVVPYSSLVLHNEKYNELFDKGNNQGKLKALLHNKAITNLLAKIAPTKPEGVLIDQFTQPDTYYKYLAKQKQVQRENVYFATKGESVHLAVAAASILARYSFVKQFNELSKKAGMPLPKGAGKQVDIAAAKLIQKLGKERLPEFVKLHFANTEKAFRLLK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL049_MIMIV
Sequence: MSFIFCDGDKDKLVDFLSRKDSWSDIELTLTNGSEKKILYVHKNILKNCRYFEGTFSFYENSYEYDNIEIEVPHINIACDIIYLFYGIELPESTDWKYKIHLHLLQEFFLLQPISVSDLKIPENDFEILINEIISFGHTDQIVKLIFNNMPESYDVGKIPQDILEIIFNSNKKIYQILDKIKNAIH
What are the official names of this protein?
Uncharacterized protein L49.
Protein: BOFH_BRAOB
Sequence: MDPEGFTSGLFRWNPTRVMVQAPTPIPPPQQQSPATPQTAAFGMRLGGLEGLFGPYGVRFYTAAKIAELGFTASTLVGMKDEELEDMMNSLSHIFRWELLVGERYGIKAAVRAERRRLQEEEEEESSRRRHLLLSAAGDSGTHLALDALSQEDDWTGLSQEPVQHQDQTDAAGINGGGRGGYWEAGQTTIKKQQQRRRKKRLYVSETDDDGNEGEDDDGMDIVNGSGVGMERQREHPFIVTEPGEVARGKKNGLDYLFHLYEQCREFLLQVQTIAKDRGEKCPTKVTNQVFRYAKKSGANYINKPKMRHYVHCYALHCLDEEASNALRSAFKVRGENVGSWRQACYKPLVDIACRHGWDIDAVFNAHPRLSIWYVPTKLRQLCHLERNNAEAAAATLVGGISCRDRLRLDALGFN
What is the function of this protein?
Controls floral meristem identity.  Is required very early in flower development and may act here as a transcription factor.
What are the official names of this protein?
Putative transcription factor BOFH.
What is the protein family that this protein belongs to?
Belongs to the FLO/LFY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COX1_CHICK
Sequence: MTFINRWLFSTNHKDIGTLYLIFGTWAGMAGTALSLLIRAELGQPGTLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSTVEAGAGTGWTVYPPLAGNLAHAGASVDLAIFHYLAGVSSILGAINFITTIINMKPPALSQYQTPLFVWSVLITAILLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHVVAYYAGKKEPFGYMGMVWAMLSIGFLGFIVWAHHMFTVRMDVDTRAYFTSATMIIAIPTGIKVFSWLATLHGGTIKWDPPMLWALGFIFLFTIGGLTGIVLANSSLDIALHDTYYVVAHFHYVLSMGAVFAILAGFTHWFPLFTGFTLHPSWTKAHFGVMFTGVNLTFFPQHFLGLAGMPRRYSDYPDAYTLWNTLSSIGSLISMTAVIMLMFIVWEAFSAKRKVLQPELTATNIEWIHGCPPPYHTFEEPAFVQVQE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS113_ARATH
Sequence: MAEQTEKAFLKQPKVFLSSKISGKGKRPGKGGNRFWKNIGLGFKTPREAIDGAYIDSKCPFTGTVSIRGRILAGTCHSAKMQRTIIVRRNYLHFVKKYQRYEKRHSNIPAHVSPCFRVKEGDHVIIGQCRPLSKTVRFNVLKVIPAGASAFGKKAFTGV
What are the official names of this protein?
40S ribosomal protein S11-3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y643_STRT2
Sequence: MRNIYDLANELERGIRALPEYKNLVEKKEAIATDAEASALFKEFTDFQEDFYAKMQAGTMPTAEEQAAVQELGQKVEANALLKEYLTAQQSLSVYLNDIERIIFKPLQELNN
What are the official names of this protein?
UPF0342 protein stu0643.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: TDIF2_HUMAN
Sequence: MVVTRSARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKAKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKKNELLQKAVITPDFEKNHCVPPYSESKYQLQKKRRKERQKTAGDGWFGMKAPEMTNELKNDLKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRIPKKQRKRTIVEELLADSEFRRYNRRKYSEIMAEKAANAAGKKFRKKKKFRN
What is the function of this protein?
Regulates the transcriptional activity of DNTT and ESR1.  May function as a chromatin remodeling protein (PubMed:12786946, PubMed:15047147).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
Deoxynucleotidyltransferase terminal-interacting protein 2, Estrogen receptor-binding protein, LPTS-interacting protein 2, LPTS-RP2, Terminal deoxynucleotidyltransferase-interacting factor 2, TdIF2, TdT-interacting factor 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: MRAZ_PSEPG
Sequence: MFRGANAVSLDAKGRLAMPSRYRDELDSRCNGQLIVTIDAVDPCLCVYPLDEWEQIEAKLRALPSLREENRRLQRLLIGNAVDLELDGSGRFLVPPRLREYAKLDKKAMLVGQLNKFQLWDEDAWNAVSAADLAAIQQPGAMPDELRDLIL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NRDI_STAAM
Sequence: MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: SAHH_SPHAL
Sequence: MATLAADTRDYVVADIGLADFGRKEINIAETEMPGLMALRAEYGASQPLKGARITGSLHMTIQTAVLIETLTALGAEVRWATCNIFSTQNHAAAAIAASGVPVFAVKGESLADYWDYVGRIFDWESDNDGRTANLILDDGGDATMFALWGAKLEAGETMPPPENEEEVEMQRALKAFIAAKPGYLTKTVKAIKGVSEETTTGVHRLYHIAKKGELPFPAINVNDSVTKSKFDNLYGCKESLVDAIRRGTDVMLAGKVATVAGFGDVGKGSAQSLRNGGARVLVTEIDPICALQAAMEGFEVVTMDEAVKRSDIFVTATGNADVITAEHMAAMKNMAIVCNIGHFDSEIQIAALANYKWTEVKPQVDLVEFPDGKQIIILSKGRLVNLGNATGHPSFVMSASFTNQTLAQIELWTRSEQYQNDVYVLPKHLDEKVAALHLEKLGVKLTKLTQKQADYIGVPVEGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDL63_ARATH
Sequence: MSSLVSRCQVIALLVLFFFGVCLAGKDIPANFVFGDSLVEVGNNNYLATLAKANNFPNGIDFGSPTGRFTNGRTIVDIIYQALGSDELTPPYLAPTTRGPLILNGANYAPGGSGPLNSPGSTNLDSWSPEQLKAMMFGVNYLAPVFFKKMDGQTIAISSLSTLSRAANLYRQILAKEVAKAIAQDTTTDLPKASHGVSSSSVKEELRPKETYFCDFYGRPIVYPILTSARRVTWARKINYDINNM
What are the official names of this protein?
GDSL esterase/lipase At4g16220, Extracellular lipase At4g16220.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEXA_CAEEL
Sequence: MRLLIPILIFALITTAVTWFYGRDDPDRWSVGGVWPLPKKIVYGSKNRTITYDKIGIDLGDKKDCDILLSMADNYMNKWLFPFPVEMKTGGTEDFIITVTVKDECPSGPPVHGASEEYLLRVSLTEAVINAQTVWGALRAMESLSHLVFYDHKSQEYQIRTVEIFDKPRFPVRGIMIDSSRHFLSVNVIKRQLEIMSMNKLNVLHWHLVDSESFPYTSVKFPELHGVGAYSPRHVYSREDIADVIAFARLRGIRVIPEFDLPGHTSSWRGRKGFLTECFDEKGVETFLPNLVDPMNEANFDFISEFLEEVTETFPDQFLHLGGDEVSDYIVECWERNKKIRKFMEEKGFGNDTVLLENYFFEKLYKIVENLKLKRKPIFWQEVFDNNIPDPNAVIHIWKGNTHEEIYEQVKNITSQNFPVIVSACWYLNYIKYGADWRDEIRGTAPSNSRYYYCDPTNFNGTVAQKELVWGGIAAIWGELVDNTNIEARLWPRASAAAERLWSPAEKTQRAEDAWPRMHELRCRLVSRGYRIQPNNNPDYCPFEFDEPPATKTEL
What is the function of this protein?
Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines.  Degrades chitotriose.
What are the official names of this protein?
Beta-hexosaminidase A, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: SCPB_CLOPS
Sequence: MSDINQIEFSEISKKDELKSIIESLLFVSGEPLALKDICRIVEEDFKYVEDLMRELMNIYNGDSSRGIKIISLNGTYQLVTKTKNSEYIQKLLKKNVRQSLSQASLESLAIICYKQPITRVEIDEIRGVKSESAIQRLVEKNLVEETGRLEVPGRPILYGTTDEFLRHFALNDLGDLPSIELFEENNEVSDMVEE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: GRPE_BORBZ
Sequence: MEKKETKSESEKTNKQDNKNTKSQKKENLNLVNSDKKIAELENEISNLKDLYLRKQAEFENFRKRLEKEKDNFVKFANETIMKDVVNFLDNLERAINSSKKSKDFDNLLTGISMIENEILSIFDKKYNLKKFGENGENFDPSRHEAISIEEKEGLKNPEIVEVYQKGYCYNDRILRTAKVKVAQSKN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BEDC1_PSEPU
Sequence: MNQTETTPIRVRKNWKTSEIETLFDEQAGRIDPRIYTDEDLYQLELERVFARSWLLLGHETHIRKPGDYFTTYMGEDPVVVVRQKDASIAVFLNQCRHRGMRICRSDAGNAKAFTCSYHGWAYDTAGNLINVPYEAESFACLDKKEWSPLKARVETYKGLIFANWDENAIDLDTYLGEAKFYMDHMLDRTEAGTEVIPGIQKWVIPCNWKFAAEQFCSDMYHAGTTAHLSGIIAGLPEDLELADLAPPKFGKQYRASWGGHGSGFYIGDPNMMLAMMGPKVTSYLTEGPAAEKAAERLGSIERGTKIMLEHMTVFPTCSFLPGVNTIRTWHPRGPNEVEVWAFTVVDADAPDDIKEEFRRQTLRTFSAGGVFEQDDGENWVEIQHILRGHKARSRPFNAEMSMGQTVDNDPIYPGRISNNVYSEEAARGLYAHWLKMMTSPDWEALKATR
What are the official names of this protein?
Benzene 1,2-dioxygenase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: RELA_SHIFL
Sequence: MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
What is the function of this protein?
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.  This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity).
What are the official names of this protein?
GTP pyrophosphokinase, (p)ppGpp synthase, ATP:GTP 3'-pyrophosphotransferase, ppGpp synthase I.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
Protein: TM6_VITVI
Sequence: MGRGKIEIKRIENPTNRQVTYSKRRNGIFKKAQELTVLCDAKVSLIMFSNTGKFHEYTSPTITTKKVYDQYQKTLGIDLWSSHYERMQENLRKLKEINNKLRREIRQRMGEDLGDLSIEDLRGLEQKMDASLGLVRERKYHVIKTQTETYRKKVRNLEEQHGNLLLNFEAKCDDPHYGLVENDGDYESAVAFANGASNLYAFRLHQAHPNLHHDGGYGSHDLRLA
What is the function of this protein?
Probable transcription factor involved in flower development.
What are the official names of this protein?
Agamous-like MADS-box protein TM6, VvAP3.2, VviAP3b.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS21_GEOSE
Sequence: MSKTIVRKNESIDDALRRFKRAVSKTGTLQEVRKREFYEKPSVRRKKKSEAARKRK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: MURI_SHEPW
Sequence: MSGPILIFDSGIGGLSILDEIRKVMPQQSCCYLFDNARLPYGELEESELISGCVSLIIEQAMRINAGIVVVACNSASTLVLTTLREQLSIPVVGVVPAIKPAAKISKRRHIGLLATPGTIKRPYTKQLIDAFAEDCRVELFGSSELVMLAEAKLAGTAVDMQKLELLLAPIRTSELDTLVLGCTHFPVLATEIKQSLGQSIILLDSGKAVADRVLSLLKGNGLPKTASNKVVDYSAVFTTDDIAQGLKKRLVEEGFTSIEPHSSTNLR
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: LOLD_XANOM
Sequence: MNEIREAVVQTPEQATAVIRAEALAKTYAEGKMRTPVFDGLDLSVATGETVAIVGASGAGKSTLLHLLGGLDIPTAGEVYVAGERMSALSDAQRGKLRNQSLGFVYQFHHLLPEFTALENVMMPVLLSGKNVAVAKGQALQLLESVGLGHRIDHKPSELSGGERQRCAVARALVNKPGCVLGDEPTGNLDDKTAGTVFELMLELNRAQRTSLVLVTHDRGLARRLDRVLELHQGKLRELAPSAV
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL31_SULIK
Sequence: MKEKDNFEMVINLRKIKTGKRTGRSKRAVKFVRKIVARHFNADKVVIDPLLAKSISKNGNDKVVSKVRVVVSKVGEKIYLVRLAIKSR
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: SOX14_CHICK
Sequence: MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGETDPLKAAGLPVGATDSLLSSPEKARAFLPPTSAPYSLLDPSQFSSSAIQKMTEVPHTLATGTLPYASTLGYQNGAFGSLSCPSQHTHTHPSPTNPGYVVPCNCTAWSASSLQPPVAYILFPGMTKTGIDPYSSAHATAM
What is the function of this protein?
Acts as a negative regulator of transcription.
What are the official names of this protein?
Transcription factor SOX-14, SRY-related protein CH60.
What are the subcellular locations of this protein?
Nucleus.
Protein: GGS_PETMO
Sequence: MSIFFDDKILQNLPKKVKVVVGIPSYNNAETISFVSKTAAEGIVEYFDSDGIIVNADGGSKDGTKEVFMKTDTKSVPKIAYDYIGLPGKGSAMLSVIELAKNLDAEAIVFLDSDLKSVRPWWIERLTGPIMKGLSDYVTPYYVRHKYDGTITNQVCYPLVSSLFGQAIRQPIGGDFGVGKNMIDVYLKAASSVAKTEVARFGIDIWMTINAILNSNKKVYQAALGAKVHDPKDPGADLSPMFKQVVGTLFDIIVDSASKWKDIGSIEEAPIYGEIPQIAVEPININIENLKMQLLEGLKNEESKILANDHLGFIMEKKKVPLQIWVDILFNALIEYSKNKDKKLVESLVPLYFGRVADFAELTKDMNEVEAEKVIKDQINLFANKKDELIEKL
What is the function of this protein?
Involved in the biosynthesis of the compatible solute mannosylglucosylglycerate through a nonphosphorylating pathway.  Catalyzes the synthesis of glucosylglycerate (GG) from ADP-glucose and D-glycerate.  Can also use UDP-glucose, with lower efficiency.
What are the official names of this protein?
Glucosylglycerate synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: HNF1A_RAT
Sequence: MVSKLSQLQTELLAALLESGLSKEALIQALGEPGPYLMVGDGPLDKGESCGGTRGDLTELPNGLGETRGSEDDTDDDGEDFAPPILKELENLSPEEAAHQKAVVESLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREVAQQFTHAGQGGLIEEPTGDELPTKKGRRNRFKWGPASQQILFQAYERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLVTEVRVYNWFANRRKEEAFRHKLAMDTYNGPPPGPGPGPALPAHSSPGLPTTTLSPSKVHGVRYGQSATSEAAEVPSSSGGPLVTVSAALHQVSPTGLEPSSLLSTEAKLVSATGGPLPPVSTLTALHSLEQTSPGLNQQPQNLIMASLPGVMTIGPGEPASLGPTFTNTGASTLVIGLASTQAQSVPVINSMGSSLTTLQPVQFSQPLHPSYQQPLMPPVQSHVAQSPFMATMAQLQSPHALYSHKPEVAQYTHTSLLPQTMLITDTNLSTLASLTPTKQVFTSDTEASSEPGLHEPSSPATTIHIPSQDPSNIQHLQPAHRLSTSPTVSSSSLVLYQSSDSNGHSHLLPSNHGVIETFISTQMASSSQ
What is the function of this protein?
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity).  Binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (By similarity).  Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity).
What are the official names of this protein?
Hepatocyte nuclear factor 1-alpha, HNF-1-alpha, HNF-1A, Liver-specific transcription factor LF-B1, LFB1, Transcription factor 1, TCF-1.
What is the protein family that this protein belongs to?
Belongs to the HNF1 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIM2_CLOBJ
Sequence: MQIRQSVKFKKPLIHYITNPISINDCANMILAVGAKPIMAEHPLEVSEITSISESLGINLGNITDNKMKSMLISGKISYEKKIPQVIDLVGVGCSKLRLDYAKKFILECHPNVIKGNMSEMKAIYGIKSSAKGIDVGACDIITEQNFDENIEMIKRLSMETGSVVAATGVVDIISNGTYTYIISNGCEMLSMITGTGCMLTGIIASYISSGNILEGTALAIVLMGICGELSQHVKGTGSFRNELIDNIFSISDDIIIKKIRINSY
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase 2, 4-methyl-5-beta-hydroxyethylthiazole kinase 2, TH kinase 2, Thz kinase 2.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: MNME_RICPR
Sequence: METIFAQSSAFGKAGVAVFRISGPKSLEVLQLLTGRKDFKPRLMYYQQIIVPETNELIDNAMVVYFKLPNSFTGEDVVEIHTHGSKAISIMLINTLLNIADIRLAEAGEFTKRAFLNNKFDLTAAEGIADLINAETIMQHRQAVRQANGGLKELYNKWRNQLLKIISLLEAYIDFPDEDIPESILNDVNNTHKNIVNEISNYLNDNRRGELLNNGLKLAIIGPPNTGKSSLLNFLMQRNIAIVSNIAGTTRDIIEGHLDIGGYPIILQDTAGIRTESTDIIEQEGIKRAINSAKTANIKIVMFDAEKLDSSINNDITGLIDENTIVIINKIDLIEPNKTFAIENRYKCLRVSVKNNIALSNILKNIENIAENLAGVTETPYITNQRHRHYLKQALSHLIDFNLDNDLVLATEDIRMTVRCIGLITGVINVEEILNEIFKNFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_ALCBS
Sequence: MPKIKTNRGAAKRFKKTASGFKRKQAFKNHILTKKSSKTIRKLRPKQEVHENDVALVKRMMPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RHDF2_CANLF
Sequence: MDSTDKNGESVSSVSSSRLQSRKPPNLSITIPPPEASAPGEQASMLPQRPRNPAYMKSVSLQEQRGRWQEGSSEKRPGFRRQASLSQSIRKGTAQWFGVSGDWEAKRQHWQRRSLHHCSVRYGRLKASCQRDLELPSQEVPSFQGTESPKPCKMPKIVDPLARGRAFRHPDEVDRPHAPHPPLTPGVLSLTSFTSVRSGHSHLPRRKRMSVAHMSFQAAAALLKGRSVLDATGQRCRVVKRSFAYPSFLEEDVVDGADTFDSSFFSKEEMSSMPDDVFESPPLSASYFRGIPRSASPVSPDGVQIPLKEYGRPPVAGTRRGKRIASKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHIIITLLVICTYGIAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWIGPSSIDLIHLGAKFSPCIRKDQQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDKSDLGQKRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQAKSNRTGFLHMDCQIKGRPCCISTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWQLLERPWKAFLNLSAIVLFLFICGLLPWIDNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSLLVFAGLFASLVIWLYVYPINWPWIEYLTCFPFTSRFCEKYELDQVLH
What is the function of this protein?
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation.  Does not exhibit any protease activity on its own.
What are the official names of this protein?
Inactive rhomboid protein 2, iRhom2, Rhomboid family member 2, Rhomboid veinlet-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane.
Protein: PTH_BURA4
Sequence: MIKLIVGLGNPGAEYTATRHNAGFWLVDQLAREAGATLRDERRFHGFYAKARLHGEEVHLLEPQTYMNRSGQSVVALASFFKILPDQILVAHDELDLPPGTVKLKLGGGSGGHNGLKDISAHLSSQQYWRLRIGIGHPRDLIPEGARAGAKPDVANFVLKPPRREEQDVIDASIERALAVMPMVVKGELDRATMQLHRN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_BACC3
Sequence: MLNPSIDSLLTKIDSKYTLVTVAAKRAREMQLANNCVVEKPVSHKCVGKALEEIDMEALSYVPSEDKVTE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.