PharMolix/UniProtQA huggingface dataset:
Protein: HEM12_PYRAR
Sequence: MDLLSPLSAVILTYREADANALGRIGEEMRRCIEVIGPKTPMFVLHTCHRVEAYLYGASEEELSSLVERYKRHVESARILRGIEAARHLFRVAAGLESMLLGETDILGQLEEAYDRQVRAGFTRGLLKTVVERAVRVGKKVRTETGISRGPAGLGSLSIIYVSQFVDLKSAKVAVLGAGAVGAGLAKELAERGVAKLYILNRTLEKATEVAKKTGAEARPLTREEVERCLLECDVVFSAVHTLEYVIDMIPPGASVKVVVDLGVPQSVAPGLPIKVVRLSDLAELAQRYSALRKEEAKKAEAIVEEELEMLPKALAKRAVEEAVAEVMARAVEIAEEEGRRAGCEVAQLAAKTTVKRLLLPIVEELKKMAENGRVEHALEVSQIFTRLVGAPHGEPQNLKTVK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase 2, GluTR 2.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: AMEL_CAVPO
Sequence: MGTWILFACLLGTAFAMPLPPHPGHPGYINFSYEKSHSNAINIDRTALVLTPLKWYQSMIRQPYPSYGYESMGGWVHHQVIPVLSQQHPPSHTTLPPHHHIPVGPAQQPVVPQQPLMPVPGHHSMTPNQHHQPNLPPTSQQPFQQPFPTQPVQPQHHQPIQPIQPIQPIQPIQPIQPQSPLHPIQPLPPQQALPPMFSMQPIAPLLPDLPLEAWPATDKTKREEVD
What is the function of this protein?
Plays a role in the biomineralization of teeth.  Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development.  Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity).
What are the official names of this protein?
Amelogenin.
What is the protein family that this protein belongs to?
Belongs to the amelogenin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MTNA_XANAC
Sequence: MNDSAHIDYARYDHIRPLLWTGDALELLDQRKLPFEVAHVRCDSSDAVAEAIHSLAVRGAPAIGIAAGWGVVLAARDIAADDGSAALQKLEPALLRLNAARPTAVNLAWALMRMRRVLGAAGADWREVIAREAQAIADEDLAANRHMGALGAALIAPGSGVLTHCNTGSLATAGFGTALGVIRAGMAQQRIAKVFAGETRPWLQGARLTVWELHQDGIDATLIADSAASHLMKSGLVQWVIVGADRICANGDTANKIGTYQLAIAARHHGVKFMVVAPSSTVDMATASGDQIEIEQRDPGELFGVGGVRTVADGIHAWNPVFDVTPGDLIDAIVTERGVIAQPDLARMQAAFGS
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: RL18_BEII9
Sequence: MAKDIEATERRKARVRRSLRARAYGKPRLSVFRSSKQIYCQIIDDGEGKTLVAASSLEKANREGLKTGATVEAAKIIGKLIAERAVQAGIKDVIFDRGAYMYHGRVKALADGAREGGLNF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SMG_SHEB9
Sequence: MFDILMYLFENYVHSEVELLVDEDELTKELTRAGFHQSEILKALTWLERLAELQEGDKPYLCNHDQHSFRIYTKDEMDKLDVESRGFLLFLEQVKVLNVETREMVIDRVMELDEPTLILEDLKWVILMVLFNAPGHESAYEQMEDLIFEQPEGRLHS
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: URIC_DROME
Sequence: MFATPLRQPAAANHQTPKNSAGMDEHGKPYQYEITDHGYGKDAVKVLHVSRNGPVHAIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKNTVYLLAKKHGIESPEKFALLLARHFINKYSHVEEAHVHVEAYPWQRVCQEETRTNVNGKCENGVQGNCDFSSIDNRSLHNHAFIFTPTALHYCDVVIRRTDPKQTVITGIKGLRVLKTTQSSFVNFVNDEFRSLPDQYDRIFSTVVDCSWEYSDTENLDFLRAWQTVKNIIIRNFAGDPQVGVSSPSVQHTLYLSERQVLDVLPQVSVISMTMPNKHYFNFDTKPFQKIAPGDNNEVFIPVDKPHGTIYAQLARKNINSHL
What is the function of this protein?
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
What are the official names of this protein?
Uricase, Urate oxidase.
What is the protein family that this protein belongs to?
Belongs to the uricase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: VSPS1_CROAD
Sequence: MVLIRVLANLLILQLSYAQKSSELIFGGRPCNRNEHRFLALVYSDGNQCSGTLINEEWVLTAAHCEGNKMKIHLGVHSKKVPNKDKQTRVPKEKFFCVSSKTYTKWNKDIMLIRLDRPVSNSKHIAPLNLPSSSPSVGSVCRIMGWGTISPTEVILPDVPQCANINLLSYSVCRAAYPEYGLPATSRTLCAGILEGGKDTCAGDSGGPLICNGQFQGIASWGSTLCGYVREPALYTKVFDHLDWIQSIIAGNTDATCPL
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine proteinase Sp1, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL20_SALTO
Sequence: MARVKRAVNAQKKRRTLLATASGYRGQRSRLYRKAKEQVLHSMQYSYRDRRDRKGDFRQLWIQRINAGARANGLTYNRLIQGLKLAGIEVDRKILADLAVNDAAAFAAIVEKARAAVAEEGTGGAAAQAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MDH_BRUSI
Sequence: MARNKIALIGSGMIGGTLAHLAGLKELGDVVLFDIAEGTPQGKGLDIAESSPVDGFDAKFTGANDYVAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLDAMVWALQKFSGLPAHKVVGMAGVLDSARFRYFLSEEFNVSVEDVTAFVLGGHGDSMVPLARYSTVAGIPLPDLVKMGWTSQDKLDKIIQRTRDGGAEIVGLLKTGSAFYAPAASAIQVAESYLKDKKRVLPVAAQLSGQYGVKDMYVGVPTVIGANGVERIIEIDLDKDEKAQFDKSVASVAGLCEACIGIAPSLK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: NHR67_CAEEL
Sequence: MMTAVSQMSVPSSRILLDVDCRVCEDHSSGKHYSIFSCDGCAGFFKRSIRRHRQYVCKNKGSPSEGQCKVDKTHRNQCRACRLRKCLEIGMNKDAVQHERGPRNSSLRRQQMMFDHGSSPNSPEMGSESDAIILPTSSMNRDTVAGTAARIFFALVGFCQNPLNGVPKERQMTMFQQNWAALLVLHATETRAITSKQIRTETISGSSEQRNAVANAFEIIERLQLDNREYMMLKHFTMWRDTPSAIQIVFQLASIQNFTHRTEPTRYIQCINAIAAIPTTSIIDVLFRPSIGSASMPRLIQDMFKPPQQPTPTSLFPMANFNLNFLLKQEKTETEEGEDIEEEDDATSSNQFDENSSTDDRSVGELDPVQLFLALNSSTQPSSASSPSSSRPRHSIRSITELLSIQEEESVNVEEV
What is the function of this protein?
Orphan nuclear receptor that binds DNA containing an extended core motif half-site sequence 5'-AAGTCA-3' (PubMed:18179707, PubMed:19906858).  In males, plays an essential role in the migration of the linker cell which guides gonad elongation during the L3 and L4 stages of larval development by negatively regulating the expression of netrin receptor unc-5 at the mid-L3 stage (PubMed:22363008, PubMed:19906858).  Involved in the regulation of non-apoptotic cell death in the linker cell, acting upstream of or in parallel to transcription factor hsf-1 (PubMed:27472063).
What are the official names of this protein?
Nuclear hormone receptor family member nhr-67.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2083_ARTS2
Sequence: MAESTAGSEAEQDGMTPVRPVEAELLVVTGMSGAGRSTAADALEDHGWYVVENLPPQMLGTLAELVSHAPQSIPKLAVVVDVRSTALFADIRAALKTLEASGVTFRVLFLDANDDVLVRRFEQGRRPHPLQEGGRILDGIASERDLLHELRDSADIVLDTSEFNVHALATAITELFSETGPVALRLNVMSFGFKYGLPVDANFVVDARFIPNPHWVPQLRPHTGLDKDVSDYVLEAEGVKSFVDRYVLAIEPVLDGYRRENKHYATIAVGCTGGKHRSVAVAMELSKKLAQYPRVTVTTTHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Arth_2083.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: TP8L3_DANRE
Sequence: MDSDSGEQSEGELSPGHESFNSKSLALQAQKKILSKMATMAVANLLTDDTSSEILDELYKASREYTKSKKEAHKIIKDVIKIALKIGILYRNHQFSPEEMETVERFKKKMNQAAMTVVSFYEVEYTFDRGILSELLLECRDLLHELVEHHLTMRSHGRIDHVFNHFADVDFLTELYGPSEDYRLNLRKICDGINKLLDEGTL
What is the function of this protein?
May act as a lipid transfer protein.
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 8-like protein 3, TNF alpha-induced protein 8-like protein 3, TNFAIP8-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: AIM41_YEAS1
Sequence: MFRQSIRPLVSNRLTFIRYNSSPAYTAAVSLLKGDLKKAMIAKDEMKKTAIRNMLSAIKNKEIALKGKSADEYSLYDMYSKLISQRKDSINEFLANKRDDLVAKEQGEMDIIKKYMDQLPVSSELDIDQNVKKLLDALKTKAGEKKVQIKEIMGEIDWKSLPTEWKTSPTAIKNSIVKQFKEIFK
What are the official names of this protein?
Altered inheritance of mitochondria protein 41, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM41 family.
Protein: COAX_FLAJ1
Sequence: MILTVDVGNTRIKAAVFEGSSVLEYFVFEKNELEKRIEKILEKFPNCSDLVVASVGDVEKQSFLSFEKQLNVHFFTHEDIFPFHNKYATPKTLGIDRMILAAGATLQFPKQNRLVIDAGTCITYDFIDENDNYLGGAISPGLRLRYETLHNYTARLPLLTLDQPHSYIGDSTAQAIHSGVVNGFVYEIDGFIDEYRSNFSNFIIILTGGDAEFLAKRLKNTIFANSNFLLESLSQTYQYKIDND
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PREP_DEBHA
Sequence: MLRLANRVSRKDSGNLGIAQLKKRLLATSGVSQGEILSKYPIGLNMHGYVIEQVQPIPEFSLVAVKLKHSRTGSEHLHLDTPNDKNNVFSVAFKTNAPDATGVPHILEHTTLCGSFKYPVRDPFFKMLNRSLSNFMNAMTGHDYTYYPFATTNAKDFENLMDVYLSSVFEPLLTHESFMQEGWRLENSDLSDPKSPIIFKGVVYNEMKGQYSNSAYYYWIKFQEAIYGSLNNSGGNPNEITDLRYEDLVDFHSSNYHPSNAKTFTYGNIELVNHLNKLNEFFESFGSRGIRTNVRKPITELNPNYESDVTVKGPLDTMSSRPIEEQYKSSITWVIGNPLDESKLYDVFKWKVLSSLLCDGHNSPFYQELIEKEYGEDFAVNYGLDATTALLSFTIGLNNLSLEKAKNLEDKVRGIFVEKIIPELQKGKESGFNDRIEAILHQIELNFKNHKPEFGIGLLSSVVSTWVNGLNPVKSLQIDHILNRFKEDYKLNGLKMFQDLLDESVLKDDTPKFKFTMEPDESFGKNLTSQETERLNKKIEALTEEDKEIIYKRSIELAEKQKKEEDVSALPTLTVKDIPREGDFYPLDFADINSKKLQKRIVDTNGLIYMNATKDISYLPSKYYEYLPLFDCCLTNLAGTSKTPITELEIKIQKLTGGVTFNVSAKTDPFDISKTNMKFMLSGMALKDKSQNVYDLWFEILTQTKFDSEDEQVVDKLFTLVKNLGQNQMNTIADSGHSYANSYSNSQLTPTKYIHNLIGGIGQVSFISDLNRKLETEGRDFLKKELLPVLKDIQRHLVNGFTDGNHSGFEYSLVGDSESVIKNEKMIKEFDDLLTANSNRVAGTNELSSLISQFNSNKLGLNNNGRSTLIDLPFQVGYASLAKLGAAYTSKDGAALRVLSQLLTFKHLHSVIREANGAYGGGLSFDGLGGCLNFYSYRDPNPLTSVQSFKDSTSVALGKMINSENNGWSPKDLQEAKLTIFQGVDAPSHISSQGSLDFLEHITDEMRQERRERFLDVTYEDLKNVTEKYLLNGSQDIVTVIGDNETLKIDSSDAQWNIKKLTA
What is the function of this protein?
Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity).  Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity).  Also degrades other unstructured peptides (By similarity).  May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
What are the official names of this protein?
Presequence protease, mitochondrial, PreP, Pitrilysin metalloproteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. PreP subfamily.
Protein: FER1_PSEPU
Sequence: MTFVVTDNCIKCKYTDCVEVCPVDCFYEGPNFLVIHPDECIDCALCEPECPAQAIFSEDEVPSGMENFIELNAELAEIWPNITERKDALPDAEEWDGKPGKIADLER
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin 1.
Protein: EF2_METVS
Sequence: MGRRAKMVEKVKSLMETHDQIRNMGICAHIDHGKTTLSDNLLAGAGMISKDLAGDQLALDFDEEEAARGITIYAANVSMVHEYNGKEYLINLIDTPGHVDFGGDVTRAMRAIDGAVVVCCAVEGVMPQTETVLRQALKEKVKPVLFINKVDRLINELKLTPEELQGRFMKIIAEVNKLIEKMAPEEFKKEWLCDVVTGKVAFGSAYNNWAISVPYMQKSGISFKDIIDYCEQEKQSELADKAPLHEVILDMAIKHLPNPLQAQKYRIPNIWKGDAESEVGKSMAMCDPNGPLAGVVTKIIVDKHAGSISACRLFSGRIKQGDELYLVGSKQKARAQQVAIFMGAERVQVPSISAGNICALTGLREATAGETVCSPSKILEPGFESLTHTSEPVITVAIEAKNTKDLPKLIEILRQIGREDNTVRIEINEETGEHLISGMGELHIEVITNTKIGRDGGIEVDVGEPIIVYRETITGTSPEIEGKSPNKHNKLYMIAEPMEESVYAAYVEGKIHDEDFKKKTNVDAETRLIEAGLEREQAKKVMSIYNGNMIVNMTKGIVQLDEARELIIEGFKEGVKGGPLASERAQGVKIKLIDATFHEDAIHRGPSQIIPAIRFGVRDAVSSAKPILLEPMQKIYINTPQDYMGDAIREINNRRGQIVDMEQEGDMAIIKGSVPVAEMFGFAGAIRGATQGRCLWSVEFSGFERVPNEIQTKVVAQIRDRKGLKSE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRE_VIBC1
Sequence: MEHYISLLVKSIFIENMALSFFLGMCTFLAVSKKVKTSFGLGVAVVVVLTIAVPVNNLVYNLVLKENALVEGVDLSFLNFITFIGVIAALVQILEMVLDRFFPPLYNALGIFLPLITVNCAIFGGVSFMVQRDYNFAESIVYGFGSGVGWMLAIVALAGIREKMKYSDVPPGLRGLGITFITVGLMALGFMSFSGVQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDM34_CANAW
Sequence: MSFKVNWNSLETEPLTNWTKELLTSALNSGKSPNILASNITIKDLNFGKIAPDFEILEIGELDRDRFRGIFKIDYQGDFHLTLHTKVQANPLNIYYHNSLEKEVCNYSQDEFITPNFLLSNEQFAIPLDLKLSDIKINGIGIIVFSKSKGLTLVFRNDPLDSIKVSSTFDTVQVLANFLQKQIENQIRDLFRETLPTLIHQLSLKYLSLDNNINEIKSKLSQQDSVSMTNNELASSLKLFDDEENEFPLIYSSKNLQKNMQLFKSRETFRLSVPKFKNIVQRTRLDKFTKSYPNLLNSLYANNADLQHRFVNNINHGHNNNSNTSSNGIPIELLVSHDDKQHYDKTDDLLKDISSIQANNFYKYSNKDAPNKPKRRRIKVHKKSKAKQDDNTVKASELQNVDSTFMDSRSISPQETIDTTSTLIESAPMTRNVSTNIKSPTLETMSTGSSSSASSQVIAHPTPKRAYQPADTTVSTTTINKENHIDYIKARNLYQDFIQMSQSPGYYDKVISNGGGIGLGNSGGNYFGFNGNGNGLERTMSASPIKHLNKDKKSINYIDTSKINEKLNQFRLDGGKNSANTNNSSGGKNFRPGFTRNESNGQQGILFEAFNFPSVAPPPPYC
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: ASB7_HUMAN
Sequence: MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQNGFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTRQPRNLQDLCRIKIRQCIGLQNLKLLDELPIAKVMKDYLKHKFDDI
What is the function of this protein?
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 7, ASB-7.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: GUN20_ARATH
Sequence: MGKLLVLMLVGMFLAFESLEALEYGDALNKSILFFEGQRSGKLPTNQRVKWRADSALSDGSLANVNLIGGYYDAGDNVKFVWPMSFTTTLLSWAAIEYQNEISSVNQLGYLRSTIKWGTDFILRAHTSPNMLYTQVGDGNSDHSCWERPEDMDTSRTLYSISSSSPGSEAAGEAAAALAAASLVFKSVDSTYSSTLLNHAKTLFEFADKYRGSYQASCPFYCSYSGYQDELLWAAAWLYKATGDKIYINYVISNKDWSQAVNEFSWDNKFVGAQALLVSEFYNGANDLAKFKSDVESFVCAMMPGSSSQQIKPTPGGLLFIRDSSNLQYVTTATTVLFHYSKTLTKAGVGSIQCGSTKFTVSQIRNFAKSQVDYILGNNPMKMSYMVGFGTKYPTQPHHRGSSLPSIQSKPEKIDCNGGYSYYNSDTPNPNVHIGAIVGGPNSSDQYSDKKSDYSHAEPTTYINAAFIGPVAALISSSG
What are the official names of this protein?
Endoglucanase 20, Endo-1,4-beta glucanase 20.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GHOT_ECO57
Sequence: MALFSKILIFYVIGVNISFVIIWFISHEKTHIRLLSAFLVGITWPMSLPVALLFSLF
What is the function of this protein?
Toxic component of a type V toxin-antitoxin (TA) system.  Causes membrane damage when induced by MqsR, slowing cell growth and leading to the formation of dormant persister cells; involved with GhoS, its antitoxin, in reducing cell growth during antibacterial stress.  Its toxic effects are neutralized by GhoS, which digests ghoT transcripts in a sequence-specific manner.
What are the official names of this protein?
Toxin GhoT.
What is the protein family that this protein belongs to?
Belongs to the GhoT/OrtT toxin family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRUA_XYLFA
Sequence: MMRYALGVEYDGSEFLGWQQLGEMGPSVQATLQQALASVADASVRVVCAGRTDAGVHGQCQVVHFDSAVTRPPRAWILGTTTRLPSSVAVRWCVPTSEDFHARFSACARRYRYRLLNRQVRPALQHQFLSWERHPLDAQAMHVAAQMLLGENDFSAFRSAQCQALHARRELQAISVRRYAEVIEICVQANAFLHHMVRNIVGSLLMVGTGERPMEWIAELLAGRDRTMAGPTASARGLVFVGPLYPAKWHLPMEVSV
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RBL1_HUMAN
Sequence: MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTIPLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNINDDFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMIRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKRLQDVVSERANH
What is the function of this protein?
Key regulator of entry into cell division (PubMed:17671431).  Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation (By similarity).  Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression (By similarity).  Controls histone H4 'Lys-20' trimethylation (By similarity).  Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters (By similarity).  Potent inhibitor of E2F-mediated trans-activation (PubMed:8319904).  May act as a tumor suppressor (PubMed:8319904).
What are the official names of this protein?
Retinoblastoma-like protein 1, 107 kDa retinoblastoma-associated protein, p107, pRb1.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTNA_POPTR
Sequence: MATNPSNGLEGDNTLQSICYHRGSLKLLDQRKLPLETTYLDIKDASDGWLAIREMVVRGAPAIAISAALSLAVEVSNLENFNGTPVEAASFLAGKLDYLVSSRPTAVNLSDAATKLKEVVSKAAAAASNCQSVFQAYIEAAEIMLADDVASNKAIGSYGARFIQNQQKDPTKLSVLTHCNTGSLATAGYGTALGVIRALHGEGVLQRAYCTETRPFNQGSRLTAFELVHEKIPATLIADSAAAALMKDSKVSAVVVGADRVAANGDTANKIGTYSLALCAMHHNIPFYVAAPLTSFDSSLSSGKEIIIEERSPKEMLNARGGLGEQVAASGISVWNPAFDVTPASLISGIITEKGVITKTGMDDFDIKDFINKAG
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS20_STRPF
Sequence: MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANPSEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SUCC_STAAW
Sequence: MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.