PharMolix/UniProtQA huggingface dataset:
Protein: GLND_BURMA
Sequence: MSASVAEPPPALSRKAEFKAAKAELLARFKSANHVTPLMHALSRATDDALRSLWQECGLPATLALVAVGGFGRGELSPHSDVDILVLLPDAHASELDERIERFIGMAWDLGLEIGSSVRTVDQCIEEASHDVTVQTSLLEARRIVGSTALFERFMLRYREALDARAFFQAKVLEMRQRHAKFQNTPYSLEPNVKESPGGLRDLQTILWIARAAGFGSSWRELDTRGLITDREARELRRNEGFLKTLRARLHVIAGRRQDILVFDLQTQAAESFGYQPTSAKRASEQLMRRYYWAAKAVTQLATILIQNIEAQLFPATSGVTRVLSPGRFVEKQGMLEIAADDVFERHPDAILEAFLLYEATRGVKGLSARTLRALYNSRDVMNNAWRRDPRNRHTFMQILQQPEGITHAFRLMNQTSVLGRYLLNFRRIVGQMQHDLYHVYTVDQHILMVLRNIRRFAVAEHAHEYPFCSQLIVNFERPWVLYVAALFHDIAKGRGGDHSALGMADARRFCREHGIEGDDAALVVWLVQHHLTMSQVAQKQDTSDPVVIKRFAELVGSERRLTALYLLTVADIRGTSPKVWNTWKGKLLEDLYRATLAVLGGAQPDAHSELKTRQEEALALLRLETVPPDAHRALWDQLDVGYFLRHDAADIAWQTRVLYRHVAADTAIVRARPSPVGDALQVLVYVKDRSDLFAGICAYFDRNGLSVLDARVNTTRHGYALDNFIVTQTEHDVQYRDIANLVEQQLAARLAESAPLPEPSKGRLSRLSRTFPITPRVDLRADERGQYYILSVSANDRPGLLYSIARVLAEHRVGVHAARINTLGERVEDVFMLDGTGLSDNRLQIQVETELLRAIAV
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: TRUB_SHIDS
Sequence: MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKLYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RPOE_STAAM
Sequence: MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALGDYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILDADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDELDEDEEVFEDEEDFND
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: CHMP7_MOUSE
Sequence: MWSPEREAQAPTGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLVLSHSRRQGVVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRGELQRESDFMASVDSSWISWGVGVFLLKPLKWTLSNMLGDHKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALSELSALCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPHAKVSPVNDVDVGVYQLMQSEQLLSRKVESLSQESERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTTEPLSLLETPQETTLYTNSVPKPRILDAELEAELEKLSLSEGGLIPSSKSPKRQLEPTL
What is the function of this protein?
ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope (NE) during late anaphase (By similarity).  Together with SPAST, the ESCRT-III complex promotes NE sealing and mitotic spindle disassembly during late anaphase (By similarity).  Recruited to the reforming NE during anaphase by LEMD2 (By similarity).  Plays a role in the endosomal sorting pathway (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 7, Chromatin-modifying protein 7.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus envelope. Note=Diffused localization, with some punctate distribution, especially in the perinuclear area. Localizes to the reforming nuclear envelope on chromatin disks during late anaphase.
Protein: MP_TYDVA
Sequence: MYPAKYQVVPSGINYSDTPVGTFEQYQPQKAGESSEHFFSKVVVALIVILFAVGIVYLAYTLFLKDLILLLKAKKQKTTTEIGFGNTPLRRPGEGNPNGGPV
What is the function of this protein?
Involved in the viral transport within, and between cells.
What are the official names of this protein?
Movement protein, MP.
What is the protein family that this protein belongs to?
Belongs to the mastrevirus movement protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: IF2_RHIME
Sequence: MTDNKDDKTLSVAGKKTLTLKPSGVTQGTVRQDMGRGRTKAVVVETKRTRGPLKHKDERPITPVAATPAARPAEQRPMPPQPSGRPAPQPQPHQPRQEQNRPRGGVVLNDLSAGEMEARRRALAEAQIRDAEEAKRRAEDEVRRRREEEERLAREKEEAARRAAEEAARPPVEAEKTEEKVEAASPAVGERRAETRPQPGRAAPAATPAAPDGAALRGRRGTESEEDERRRSGAGAPRGKVVRPEPAKPAPRAKGDEGRRQGKLTLTTAAVDEDGSQRGRSLSAMRRRQEKFKRSQMQETREKISREVVLPETITIQELSQRMSERAVDVIKFLMKEGQMMKPGDLIDADLAELIAGEFGHTVKRVSESDVEEGIFNISDVDDDMQSRPPIVTIMGHVDHGKTSLLDAIRHANVVAGEAGGITQHIGAYQVEQNGQKITFIDTPGHAAFTAMRARGAQATDIAVLVVAADDSVMPQTIESINHAKAAGVPIIVAINKIDKPSANPQKVRTELLQHEVFVESMGGEVLDVEVSAKNQTNLDKLLEAILLQSEILDLKANPNRTAEGTVVEAELDRGRGAVATVLVQKGTLTPGQIIVAGDQWGRVRALVNDKGEHVKAAGPSTPVEVLGLSGTPAAGDRFAVVESESRAREISEYRQRLAREKAVARQSGSRGSLEQMMTQLQTSGVKEFPLVIKGDVQGSIEAISGALDKLGTDEVRARIVHSGAGGITESDVSLAEASNAAIIGFNVRANKQARDASERAGIEIRYYNIIYDLVDDVKAAMSGLLSPERRETFLGNAEILEVFNITKVGKVAGCRVTEGKVERGVGVRLVRDNVVIHEGKLKTLKRFKDEVSEVQSGQECGMAFENYEDIRAGDTIECFRVEHVTRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYC2_MARMO
Sequence: MRSCTVSTMPRMICRNADLEFDWLQPCFYPDEDDFYFSGPNSTPPGEDIWKKFELLPTPPLSPSCAFLELSTEPSDWASEMMLTEADLWGNPDEEDVFGPGGLGSLTPNPVILRDCMWSGFSAREKLERAMSEKMQHGHEPAATGPATQVPGAGAASPAGRGHSGTAGAALPAELAHPAAECVDPAVVFLLPVSKRNPVPVRVAPARAPARASAVGAAVARAAAPATAAVAAPPGLSSRPPNGGDHKVLSTSGEDALSDEVDEEEDEEEEIDVVTVEKSCKTGGTTFTLTVSPKNTALGLGREQSRELILQRSVPIYQQHNYAAPSPYVESEDAPPQKKIKREVSPHPLKSVIHPKGKSFSPRKSDSEDSVRRRNHNILERQRRNDLRSSFTTLRDHVPELVKNEKAAKVVILKKACEYVHYLQAKEHQLLMEKEKLQARQQQLLKIIELAWTF
What are the official names of this protein?
N-myc 2 proto-oncogene protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: KATG_PERMH
Sequence: MDKKECGFSIDDFLYAVEGGNTISKWWPHRLNLKILQQNNPDLVPFDKNFNYREEFSKLDYFELKEDIRRIMRESQEWWPADYGHYGPLFIRMAWHSAGTYRIIDGKGGANGGNQRFAPVNSWPDNVNLDRARRLLWPVKKKYGNKISWADLMILAGNVALEDMGFKTIGFGGGREDIWEPEIDTYWGPETEWLADMRHSEEGKIKGPLAAVQMGLIYVNPEGPNGEPDVLGAAKDIKESFGKMGMSIEETVALIAGGHTFGKCHGAADPSKYLGPEPEAAPIEQQGLGWKNSYGTGKGKDTITSGLEGAWTPTPIKWDNSFLRILFKYEWNLQKSPAGAWQWVAVNPDREDLVPDAHIPGKYHPPIMLTTDLALKLDPELSEVSKRFLEDPEYFRDAFAKAWFKLTHRDLGPKWRYLGPEVPEEDFIWQDPIPEINYQLIDQDDIKNLKEKILKSDATVTELVYTAWSAASTFRKSDRRGGVNGGRIALEPQISWEVNKTHVPKVLKILNEIKEDFNKQSSDKKVSLADLIVLAGCAAVEEAIKRAGFDIQVPFRPGRNDTTQELTDIKSFSFLEPVADGFRNYIKPECDIPEEYLLIDKADQLNLTVPQMCVLVGGLRVLGANYDSTDYGVFTDNVGTLSNDFFVNLLDMSIVWKPVRVNNRDIFEGYDRKTGDLVYRGTRVDLIFGSNSELRAQAEFYAQDDNREKFIRDFVEAWDKVMNLDIT
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: SCAF_BPT4
Sequence: MLKEQLIAEAQKIDASVALDSIFESVNISPEAKETFGTVFEATVKQHAVKLAESHIAKIAEKAEEEVEKNKEEAEEKAEKKIAEQASKFIDHLAKEWLAENKLAVDKGIKAELFESMLGGLKELFVEHNVVVPEESVDVVAEMEEELQEHKEESPRLFEELNMRDAYINYVQREVALSESTKDLTESQKEKVSALVEGMDYSDAFSSKLSAIVEMVKKSNKDESTITESINTPDTEAAGLNFVTEAVEDKAAQGAEDIVSVYAKVASRF
What is the function of this protein?
Cleavage product of Gp22 that is incorporated into the mature phage head.
What are the official names of this protein?
Capsid assembly scaffolding protein, Gene product 22, gp22, Head morphogenesis protein, Scaffold protein.
What is the protein family that this protein belongs to?
Belongs to the T4likevirus capsid assembly scaffolding protein family.
What are the subcellular locations of this protein?
[Internal peptide VII]: Virion.
Protein: MDH_SHESH
Sequence: MKVAVLGAAGGIGQALALLLKTQLPAGSKLSLYDIAPVTPGVAVDLSHIPTAVEVKGFAGEDPTPALEGADVVLISAGVARKPGMDRSDLFNINAGIVRNLVEKCAAACPKALIGIITNPVNTTVAIAAEVLKAAGVYDKNRLFGVTTLDVIRSETFIAEAKGLNVDDVKINVIGGHSGVTILPLLSQVQGVSFSDEEVAALTTRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLVRGLQGEENVIECAYVDGGSEHADFFAQPILLGKNGVESVLAYGEVSEFEANARDAMLDTLKADIKLGVEFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: TBA2_PELFA
Sequence: MRECISIHIGQAGIQTGNACWELYCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKHVPRAVYVDLEPTVCDEVRTGTYRQLYHPEQIISGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADNCTGLQGFLVFHATGGGTGSGLGSLLLERLSVDYGRKSKLSFAITPAPQVATAVVEPYNSVLSTHALLEHTDCTFCLDNEALYDVCRRNLDIERPTYTNLNRLVAQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLTSYAPIISAEKAYHEQLSVAEITNSVFEPAGMMTNCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLARVQRAVCMVANTTAIAEALSRIDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGAETAEGEGEEEDFGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYE_MYCCT
Sequence: MSFRLRYAPSPTGFLHIGNTRTALMNYLFAKHYNGSFIVRIEDTDLARNVEGAIESQFENLNWLGIYPDESIFNPNDQKYGKYMQSQKFDRYKQLAEQLVDQNKAYRCFCTSEELEKDYEDQTSKGIIATKYSQKCLFLTQDQIQKNLENKKEYSIRFKVPKNKTWTINDIVRGDVSFDSKDLGDFVILKSNGVATYNFAVVVDDYDMQITHVLRGEEHISNTPRQMMIYDAFNWNYPMFGHLTLIVDNTGKKLSKRSGNALFFIEQYKKQGYLSQAIFNYIALLGWSPPGEQEILSQNELIKIFDEKRFSKSPSTFDMVKMKWINSVYMKKLDDDKYLEFVKSFINTNKFDITSKSETWLNHLLLLYKKELEYAEQINDHLDLFFNKNTLDNNTIDVLNNLTNYKNVVEIFKNQINVLKDWTIENIKQIIKDTSTLANVKGKDLFMPIRIFATKSEHGPSLADVIYLLGKTTVLNNINSLER
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_STRP7
Sequence: MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTPDKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFSTLTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB2_ARATH
Sequence: MAASLVRSCCSRASRAITTVRFMSNVPEDTVYGGPKPQNSNQRVTLTQLRQKHRKGEPITMVTAYDYPSAVHIDTAGIDVCLVGDSAAMVVHGYDTTLPISLEEMLVHCRAVARGAKRPLLVGDLPFGTYESSTNQAVDTAVRVLKEGGMDAIKLEGGSPSRITAAKSIVEAGIAVMGHVGLTPQAISVLGGFRPQGKNIASAVKVVETAMALQEAGCFSVVLECVPPPVAAAATSALNIPTIGIGAGPFCSGQVLVYHDLLGMMQHPHHAKVTPKFCKQYAQVGEVINKALLEYKEEVSKHLFPGPSHSPYKISSSDLDGFLSELQKLGLDKAASDAAASAEKMDHSDSPSSQ
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 2, mitochondrial, Ketopantoate hydroxymethyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MURD_CALS8
Sequence: MDLFGKKVLVIGMGKSGISSARFLKKHGAYVVAFDEKREDEMKTQQKETIRKFADELYFNDLPDAVVDTSDMVVISPGVPLTKRYITLAHKRGIEVIGEIELAYRFCRSKNIVAITGTNGKTTTTTLVGEILKKVFDNVIVCGNIGFPFIDYVESSTDDTIFVIEISSFQLETIKYFKPMVGCILNITPDHLNRHMNMDNYIRAKMRIFENIDQEGYSVLNMDNSITRDLIGCAKGTVITFSKNESDTQNSVFVDGDFIYRNFLGKVEKVMRKDDIFMPGEHNLENTLAAIGCVLPFEIQPSIIEKTLKEFKGVEHRIEFVREINGVRFYNDSKGTNTDASSKALNSFEVPIILIAGGYDKGESFEKFAKLISQKVKKVFLLGQTKQKIADQLQKIGYLNFEFVEDLKEAVKKSFEIAKEGDVVLLSPACASWDMFESYEQRGRLFKQYVNEL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRC6_CLAL4
Sequence: MDRNNVLVLGPPKSGKIRFAQFISGDYETETISDDSHSGLMYKCNLKTKYFSVDVNLLIEEFPESRKEPEEKWISSLQTWFGEFESDTMADLREVIEGVVFTVCVNEWDDNVIKQQLDILSNMKDLLKDNDPFFIVMGVSEHDIEQDTMADLEDLVLLNGFEFVYFNDSGMNEFRDKMGKDRLLEVLETHEWTQKHLTHVSNEDYMAYKKEKMTSMTQGLLQEDDCNIPTLDVLLQKLQIEKSKVEEMKENERKGYVDGLVDEFLEYF
What is the function of this protein?
Involved in gross chromosomal rearrangements (GCRs) and telomere healing.
What are the official names of this protein?
Increased recombination centers protein 6.
What is the protein family that this protein belongs to?
Belongs to the IRC6 family.
Protein: EX7L_STRTD
Sequence: MSDYLSVTSLTKYLKMKFDRDPYLERVYLTGQVSNYRRRPSHQYFSLKDEGAVIQATIWAGVFKKIGFDLEEGMKINVVGRVQIYEPSGSYSLIIEKAEPDGIGALALQFEQLRKKLTAEGYFDDRHKQPLPNFVKKIGVITSPSGAVIRDIITTVSRRFPGVEILLFPTKVQGDGAAQEIVENIQKANQREDLDLLIVGRGGGSIEDLWAFNEEIVVQSIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPISKADTLAWIRERQNRAYQACLRRIQYNQERLAKLSQSVVFRQPERLYDGYLQKLDRLTTRLETFMSQDFERKQKSAEFLRQRLHGLNLSTRVKNYQDRRESLQRLLVTTTKNTINGNRVRLEKAQDALLSLDTSRIVARGYAIVNKNDKPLTTIKDITEGEQLTIQMRDGQLEVEVKNVNEKNI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_VIBC3
Sequence: MKRAFILVLDSFGIGATADAQAFGDVGSDTLGHIADQCAQGLADNAERKGALQLPNLSKLGLAMAHKESTGRFAPGLDERADIIGAYAHAAELSSGKDTPSGHWEIAGVPVLFEWGYFSDKQNSFPKELTDRILARAGLDGFLGNCHASGTQVLDDLGEEHMRTGKPIFYTSADSVFQIACHEETFGLARLLELCQIAREELADYNIGRVIARPFVGPGKGQFARTGNRRDLSVEPPSATVLQKLVEEKQGRVVSIGKIADIYAYCGITDKVKATGIPDLFEATLEQIKQAGDNTIVFTNFVDFDSAYGHRRDVAGYAAALEYFDKRLPEVLALMQEDDILILTADHGCDPTWPGTDHTREHIPVLVYGKKVAPGSLGRRDTFADIGQTLASYFGTSPMDYGKNFL
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_MYCLE
Sequence: MIVSFRPTADLVDSIGVDVRSCDLQFRQFGGCSEFAGPISTVRCFQDNALLKSVLSQTSAGGVLVVDGAGSLHTALVGDVIAELAHSNGWAGLIVNGAVRDAAALRGIDIGIKALGTNPRKSTKIGTGERHVEVNLGGVTFVPGEVVYSDDDGIVVV
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: QCRB_MYCTO
Sequence: MSPKLSPPNIGEVLARQAEDIDTRYHPSAALRRQLNKVFPTHWSFLLGEIALYSFVVLLITGVYLTLFFDPSMVDVTYNGVYQPLRGVEMSRAYQSALDISFEVRGGLFVRQIHHWAALMFAAAIMVHLARIFFTGAFRRPRETNWVIGSLLLILAMFEGYFGYSLPDDLLSGLGLRAALSSITLGMPVIGTWLHWALFGGDFPGTILIPRLYALHILLLPGIILALIGLHLALVWFQKHTQFPGPGRTEHNVVGVRVMPVFAFKSGAFFAAIVGVLGLMGGLLQINPIWNLGPYKPSQVSAGSQPDFYMMWTEGLARIWPPWEFYFWHHTIPAPVWVAVIMGLVFVLLPAYPFLEKRFTGDYAHHNLLQRPRDVPVRTAIGAMAIAFYMVLTLAAMNDIIALKFHISLNATTWIGRIGMVILPPFVYFITYRWCIGLQRSDRSVLEHGVETGIIKRLPHGAYIELHQPLGPVDEHGHPIPLQYQGAPLPKRMNKLGSAGSPGSGSFLFADSAAEDAALREAGHAAEQRALAALREHQDSIMGSPDGEH
What is the function of this protein?
Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis.  The bc1 complex catalyzes the oxidation of ubiquinol and the reduction of cytochrome c in the respiratory chain.  The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.  The cytochrome b subunit contains two ubiquinol reactive sites: the oxidation (QP) site and the reduction (QN) site.
What are the official names of this protein?
Cytochrome bc1 complex cytochrome b subunit, Cytochrome bc1 reductase complex subunit QcrB, Ubiquinol--cytochrome c reductase cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Z856_ENCCU
Sequence: MKQDAGLGFRLWVESVVSRVLPGADVSEVLLPDTATKIYVFCVDGRVLFNLSDLVDILKCFGVCADSSQICEYMRSTGRVERLEQLKDLFGEEGLEVVCSSVFSDKLLQEIGSSIRSAKGPECFKDAGPELSHPRFSIGEYKFGCQREGRDGFHNVNELYPFNHQWTDSIMDGILKNIYTSDGKRMEDGCTGKERPAFIKAGSRGRHMKHSGSLKDRPFVCTYNDCKRAFKRYEHLKRHNLMHTGERPHKCRFPGCSKAFSRSDNLSQHYKVHSTTNEMHTRSYGSYRYLNKEFN
What are the official names of this protein?
Zinc finger C2H2 protein ECU08_0560.
Protein: RL35_THIDA
Sequence: MPKMKSKSGAAKRFRALGGGGFKRSHAFMRHILTKKSTKRKRQLRGMETVNASNHKAVARMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: NPLP1_DROME
Sequence: MQAVLQSAHSSRRLMLLLSMLLNAAIQPRSIIVSATDDVANVSPCEMESLINQLMSPSPEYQLHASALRNQLKNLLRERQLAVGEEQPLGEYPDYLEEDKRSVAALAAQGLLNAPKRSLATLAKNGQLPTAEPGEDYGDADSGEPSEQKRYIGSLARAGGLMTYGKRNVGTLARDFQLPIPNGKRNIATMARLQSAPSTHRDPKRNVAAVARYNSQHGHIQRAGAEKRNLGALKSSPVHGVQQKREDEEMLLPAAAPDYADPMQSYWWYPSYAGYADLDWNDYRRAEKRFLGRVLPPTRATASTHRSRL
What is the function of this protein?
Acts as a ligand for the receptor-type guanylate cyclase Gyc76C (PubMed:21893139).  Stimulates Gyc76c-dependent cGMP production and modulates the IMD innate immune pathway in response to salt stress by inducing nuclear translocation of NF-kappa-B protein Rel which leads to increased expression of the antimicrobial peptide diptericin (PubMed:21893139).  Does not appear to play a role in Gyc76C-mediated wing development (PubMed:26440503).
What are the official names of this protein?
Neuropeptide-like 1.
What are the subcellular locations of this protein?
Secreted.
Protein: YCZO_BACSU
Sequence: MTEKKQQNKPNENPEHNDLTDPIPNEELKENMNDEKHKRQQRDNSQSERDYDTK
What are the official names of this protein?
Uncharacterized protein YczO.
Protein: CIKS_HUMAN
Sequence: MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPTMLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCSAVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSLGGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPLRSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQPALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQPPNRAGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDTAMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL
What is the function of this protein?
E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling (PubMed:19825828).  Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein (PubMed:19825828).  Essential adapter molecule in IL17A-mediated signaling (PubMed:19825828, PubMed:24120361).  Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys-63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways (PubMed:19825828).
What are the official names of this protein?
E3 ubiquitin ligase TRAF3IP2, Adapter protein CIKS, Connection to IKK and SAPK/JNK, E3 ubiquitin-protein ligase CIKS, Nuclear factor NF-kappa-B activator 1, ACT1, TRAF3-interacting protein 2.
Protein: CNPD3_PSEAI
Sequence: MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILATGDVSQDGSLDSYTRFRRLSAPLAAPLRWFAGNHDEREPMQRATEGSDLLEQIVDVGNWRVVLLDSSIPGAVPGYLEDDQLDLLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNPQALFDLLAPYPQLRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGYRWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
What is the function of this protein?
Hydrolyzes cAMP to 5'-AMP.  Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.  Specifically required for regulation of virulence factors.  Can also hydrolyze cGMP, but cGMP is unlikely to be synthesized by P. aeruginosa and cAMP is probably the biologically relevant substrate for CpdA in vivo.
What are the official names of this protein?
3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, 3',5'-cyclic AMP phosphodiesterase, cAMP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-III family.