PharMolix/UniProtQA huggingface dataset:
Protein: ATPF_HELPY
Sequence: MFVVKMVLGFLILLSPLCATGLDISQTDIIERSLNFLLFVGILWYFSAKKLRSFLRSKSLEISKRLEEIQAQLKVSKENKKKLLKELEQAKEKAELIVSDANKEAYMITQKYELQTKMDVENLIKNSKALMDLEVKKIKRELVESVFKDLRESKKVSFNAQDCVNILKQRL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ARLY_TRIV2
Sequence: MTEKQTWSQRFESALHPAIALFNASISFDIELIEYDLTGSQAHAQMLAHTGIISPAEGEQLVAGLEQIREEYRQGKFQPGIDAEDVHFAVERRLTEIVGDVGKKLHTARSRNDQVGTDTRLYLRDQISQIKTQLREFQRVLLDIAEQNVETLIPGYTHLQRAQPVSLAHHLLAYFHMAQRDWERLGDVYRRVNISPLGCGALAGTTFPIDRHYTAKLLQFERIYENSLDGVSDRDFAIEFLCAASLIMVHLSRLSEEIILWASEEFRFVTLKDSCATGSSIMPQKKNPDVPELVRGKTGRVFGHLQAMLVIMKGLPLAYNKDLQEDKEGLFDSVNTVKACLEAMTILLQEGLEFRTQRLAEAVTQDFSNATDVADYLAARGVPFREAYNIVGKVVKTSIAAGKLLKDLTLEEWQEIHPAFATDIYEAISPRQVVAARNSYGGTGFAQVSKAVSAAREEIGE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_ACIB3
Sequence: MATMQCDVVSVKESIYSGAVTMLIAKGAGGELGILPGHAPLVTLLQPGPIRVLLENGTEEIVYVSGGVLEVQPHVVTVLADTAIRADNLDEAAILEARKNAEQLLANQKSDLDSAAALAALAETAAQLETIRKIKNRAQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRMB_HAES1
Sequence: MTEQKITFADQKRKTVEIAEFTEDGRYKRKVRSFVLRTGRLSEFQRNMMNNNWATLGLEYQTTAFDFTQIYGNTNPVILEIGFGMGKSLVEMALQNPDKNYLGIEVHTPGVGACIAYAVEKQVKNLRVICHDATEILQDCIADNSLAGLQLFFPDPWHKTKHHKRRIVQPHFVEKIQQKLVPNGFVHMATDWENYAEYMLEVLTSAVGLRNTSATNDYIPRPDFRPLTKFEQRGHKLGHGVWDLFFIKNIT
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: CLD18_MOUSE
Sequence: MATTTCQVVGLLLSLLGLAGCIAATGMDMWSTQDLYDNPVTAVFQYEGLWRSCVQQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGILFIISGICAIIGVSVFANMLVTNFWMSTANMYSGMGGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLTPDDSNFKAVSYHASGQNVAYRPGGFKASTGFGSNTRNKKIYDGGARTEDDEQSHPTKYDYV
What is the function of this protein?
Required for the formation of the gastric paracellular barrier via its role in tight junction formation, thereby involved in the response to gastric acidification.
What are the official names of this protein?
Claudin-18.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Note=Localizes to tight junctions in epithelial cells.
Protein: PSF2_CANGA
Sequence: MALPAHLQETFSPEEVQFLVEEETVKIFPRITTRQKRRDKNRGAYGDVDTKWSMLTTENDNLNNMVAMRSTEVKLWIALLLKQQNKCSIVAPSWLTLRELNRKIQQETNNSDRFCDLPWNWLVIANVLFAKAADDFHDPVHELRSKVQDLREIRQTKVLKGLKQLNASHLQLDNLSLLEINELRPFIVRTMDKLREIHDSANTDGGVVDGDEEEI
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.  Has a role in chromosome segregation (By similarity).
What are the official names of this protein?
DNA replication complex GINS protein PSF2.
What is the protein family that this protein belongs to?
Belongs to the GINS2/PSF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRHO_VIBA3
Sequence: MSQYVVCALYKFVALDDYQEIRQPLTEVLEANQIRGTLLLASEGINGTVAGKRESIDALLQWFKQDSRLADVVYKESFNEEQPFNRTKVKLKKEIVTMGVEGIDPRHVVGTYVKPNEWNALISDPDVILVDTRNDYEVDIGTFKNAVNPNTETFREFPQYVEDNLDPKKHKKVAMFCTGGIRCEKSTAYMKEQGFDEVYHLEGGILKYLEEVPEEESMWEGDCYVFDGRVAVNHQLEKSGYDVCNACRLPITDEDKASDHFEKGVSCPKCIDKHSDEQKARFREREKQVQLSNARGETHVGGDAAHLIDQRKKEKLAHKEQQRSGKKAK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: HIS4_MYCBP
Sequence: MMPLILLPAVDVVEGRAVRLVQGKAGSQTEYGSAVDAALGWQRDGAEWIHLVDLDAAFGRGSNHELLAEVVGKLDVQVELSGGIRDDESLAAALATGCARVNVGTAALENPQWCARVIGEHGDQVAVGLDVQIIDGEHRLRGRGWETDGGDLWDVLERLDSEGCSRFVVTDITKDGTLGGPNLDLLAGVADRTDAPVIASGGVSSLDDLRAIATLTHRGVEGAIVGKALYARRFTLPQALAAVRD
What is the function of this protein?
Involved in both the histidine and tryptophan biosynthetic pathways.
What are the official names of this protein?
Phosphoribosyl isomerase A, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, N-(5'-phosphoribosyl)anthranilate isomerase, PRAI, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIB_CHRVO
Sequence: MSISRSLKIVATLYRYGLDDFLEGHSRLAFLHKLFGLCPVRRDTSAPLPQRVRLALESLGPIFVKFGQVLSTRRDLLPPEYADELALLQDRVPPFDGDIARQVVERSLGRKVEELFVDFDLKPVASASVAQVHKAWLRQPDGGRGREVAVKVLRPGILPVIEQDLSLMRTLAGWVEKLFADGKRLKPREVVAEFDKYLHDELDMMHEAANASQLRRNFKGSDMLIVPEVFYDYSSREVLTLEWMHGIPVGQIERLREAGVDLQKLSRFGVEIFFTQVFRHGFFHADMHPGNIFVAADGRYIALDFGIVGSLTDTDKHYLAVNFLAFFNRDYHRVATAHIESGWVPRDTRAEELEAAVRTVCEPIFEKPLSEISFGMVLLRLFETSRRFNVEIQPQLVLLQKTLLNIEGLGRQLDPELDLWDTAKPFLTKWMNEQIGWRGLLRTLKHEAPQWATTLPTLPRKLNEALGSAKTDLLVEGYIQLMREQKRQNFLLLLIAILLAALLAKSLL
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NIFD_BRADU
Sequence: MSLATTNSVAEIRARNKELIEEVLKVYPEKTAKRRAKHLNVHQAGKSDCGVKSNIKSIPGVMTIRGCAYAGSKGVVWGPIKDMVHISHGPVGCGQYSWGSRRNYYVGTTGIDSFVTLQFTSDFQEKDIVFGGDKKLDKILDEIQELFPLNNGITIQSECPVGLIGDDIEAVSRAKSKEYGGKTIVPVRCEGFRGVSQSLGHHIANDAVRDWIFGHIEAEGKPKFEPTPYDVAIIGDYNIGGDAWSSRILLEEMGLRVIAQWSGDGSLAELEATPKAKLNILHCYRSMNYISRHMEEKFGIPWCEYNFFGPSKIADSLRRIAGYFDDKIKEGAERVIEKYQPLVDAVIAKYRPRLEGKTVMLYVGGLRPRHVIGAYEDLGMDVIGTGYEFGHNDDYQRTAQHYVKDSTLIYDDVNGYEFERFVEKLQPDLVGSGIKEKYVFQKMSVPFRQMHSWDYSGPYHGYDGFAIFARDMDMAVNSPIWKRTKAPWKEAPSAKLQAAE
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein alpha chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: Y2081_MYCTU
Sequence: MFANAGLSPFVAIWTARAASLYTSHNFWCAAAVSAAVYVGSAVVPAAVAGPLFVGRVSATIKAAAPSTTAAIATLATAANGQLRERGGAGGWVGVHCPVVGGGGVGHPRKAIAAAVSVHSTCMPAAFGGHLGLGDRSRSVSLSGTP
What are the official names of this protein?
Uncharacterized protein Rv2081c.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPA_ARCFU
Sequence: MIDRSLIVFFTACYPTAEKTVEFMLTAAESGADVIELGVPFSDPVADGKTIQESYVRALRNFRVERVFEIAKAFRAESDKPLVLMSYYNPIYRRGVESFVEKAYSSGIDAMLVVDLPYDEAGDFVEVCSRTGMKNVFLAAPNTPEDRLRAMDELSAFVYLVSTYGVTGERDRISPLAFEALKRAKGICRKPVAVGFGVSKADHVRQLISAGADGVVVGSAFVRLINEKGERATEDIRALTENLRSGLV
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: SYT_COXBU
Sequence: MPTIQLPDGSVKQFSKPVSVQAVAESIGTSLAKPALAGKIDDHLVDVSFIIDKDVSLRIITEKDPEGLEVIRHSAAHLLAHAVKELFPKAEVTIGPVVEDGFYYDFAFERSFTPEDLEKIEEKMRSLAKADLAVERRVLSRDEALTLFKKMGERYKVEIIRDIPKEEILTAYQQGDFIDLCRGPHVPRTGMLKAFKLTKLAGAYWRGDSNNEMLQRIYGTAWADTKALKAYLYRLEEAEKRDHRLLAKKMDLFHFQPESPGNVFWHPNGWSIILQMREYIRHITHKYGYQEVHTPQLIDASLWDKSGHLEKFGDDIFSLPLEPQQYVIKPMSCPAHVQIFNQGVKSYRDLPLRYAEFGACHRNEPSGTLHGLMRLRGFVQDDAHIFCTEDQIQSEVSAFIDQLHEVYADFGFTEVIHKLSTRPEKRVGSDEVWTKAEQALAEALNRKGVEWDILPGEGAFYGPKIEFSLRDCLGRIWQCGTVQVDFSVPERLGAHYIAEDGSKKPPVMIHRAILGSFERFLGILLEESAGKLPLWLAPVQVVVMNITDRQADYVGQTVENLQNLGIRAHSDLRNEKIGFKIREHTIARVPYLVVIGDREVADKTLSVRALEDEASTTITLEEFARQLKAEISQRSRKSPAPSPLFPVGGES
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLAV_HAEIN
Sequence: MAIVGLFYGSDTGNTENIAKQIQKQLGSDLIDIRDIAKSSKEDIEAYDFLLFGIPTWYYGEAQADWDDFFPTLEEIDFTDKLVGIFGCGDQEDYADYFCDAIGTVRDIIEPHGAIVVGNWPTEGYNFEASKALLEDGTFIGLCIDEDRQPELTAERVEKWCKQIYDEMCLAELA
What is the function of this protein?
Low-potential electron donor to a number of redox enzymes.
What are the official names of this protein?
Flavodoxin.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: KCY_GEOTN
Sequence: MERRICIAIDGPAAAGKSTVAKLIANRLSYVYIDTGAMYRALTYRALQCGVDIHDEQALLSLLGDTSIELKPSPQGQLVFVNGEDVTDIIRGEAVTNAVSFVAKHPLVREEMVARQRALAEGGGVVMDGRDIGTNVLPNAEVKIFLKASVEERARRRHEENIARGFPSDLEKLKEEIAHRDRIDSERETAPLRKAPDAVEIDTTSLTVEEVAARIMEIVNERIG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_HAEIN
Sequence: MDLNTILIIVGIVALVALIVHGLWSNRREKSKYFDKANKFDRTSLTSRSHTQEEMVQPNNISPNTYVENGHTPIPQPTTEKLPSEAELIDYRQSDKSVDDIKISIPNTQPIYDMGNHRSEPIQPTQPQYDMPTANNVASMTLEQLEAQSQNVGFNGINSSSPELRVQLAELSHEEHQVDYNLSFNEPKAETTAHPKQTTGYIQLYLIPKSSEEFNGAKLVQALENLGFILGKDEMYHRHLDLSVASPVLFSVANLEQPGTFNAYNLAEFNTIGIVLFMQLPSPGNNLANLRMMMRAAHTLAEDLQGVILTEEQEIFDANAEQAYLARV
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: RR3_NICTO
Sequence: MGQKINPLGFRLGTTQGHHSLWFSQPKNYSEGLQEDQKIRDCIKNYVQKNMRTSSGVEGIARIEIKKRIDLIQVIIFMGFPKLLIESRPRGIEELQTTLQKEFNCVNRKLNIAVTRIAKPYGNPNILAEFIAGQLKNRVSFRKAMKKAIELTEQADTKGIQIQIAGRIDGKEIARVEWIREGRVPLQTIRAKIDYCSYTVRTIYGVLGIKIWIFLDQE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYS_THET2
Sequence: MVDLKRLRQEPEVFHRAIREKGVALDLEALLALDREVQELKKRLQEVQTERNQVAKRVPKAPPEEKEALIARGKALGEEAKRLEEALREKEARLEALLLQVPLPPWPGAPVGGEEANREIKRVGGPPEFSFPPLDHVALMEKNGWWEPRISQVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSFGKDVRGLMRVHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLNNTALATPRILAMLLENHQLQDGRVRVPQALIPYMGKEVLEPCG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLE_SERP5
Sequence: MNKDNVKLAIAPIGWTNDDMPDLGKENTFQQCVSEMALAGFTGSEVGSKYPRDPAVLKPMLDIRGIQICNAWFSTFFADGLKEKTIDEFINHMNFLHAMGAKVIGCSEQSKSIQGTTKGVFEEKPYFSDEEWQRVADGYNELADIAKGKGMQVCLHHHMGTGIQTTAEIDRYMSMVNDDVYLLFDTGHAYYSEGSQQAMMAILEKYLPRINHVHLKDVRDEVVAEVKANKLSFLDGVKKGTFTVPGDGVIDFRPVFKLLDERGYKGWMVVEAEQDPALANPFEYAVKARRYIKETAGI
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: HIS6_COLP3
Sequence: MLARRIIPCLDVRDGKVVKGVQFRNHEIIGDIVPLAKQYAEAGADELVFYDITASSDGRVVDKSWVSRIAEVIDIPFCVAGGIKSENDAKEILMMGADKISINSPALRDPDLITRLADVFGQQCIVVGVDSFYNKETDEYQVYQFTGDEKRTQQTGWNTFDWIEKVVSLGAGEIVLNCMNQDGVRQGYDIEQLKQARAKCSVPLIASGGAGTIEHFSDVYQQADVDGALAASVFHKGIIPIKDLKIYLKEQNIEVRPC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATAD2_MOUSE
Sequence: MSLLKMRRHAIHSSDSTSSSSSEDDCFERRTKRNRNRAINRCLPLNFRKDEIRGIYKDRMKIGASLADVDPMQLDTSVRFDSVGGLSSHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSRGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPAIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDREFLFSLPDKNARKEILKIHTRDWNPKPVDMFLEELAEHCVGYCGADIKSICAEAALCALRRRYPQIYTTSEKLQLDLSSITISAKDFEAALQKIRPASQRAVTSPGQALSAIVKPLLQNTVHRILDALQKVFPHVEVGTNKSLNSDVSCPFLESDLAYSDDDTPSVYENGLSQKENLNFLHLNRNACYQPMSFRPRLLIVGEPGFGQSSHLAPAVIHALEKFTVYTLDIPVLFGISTTSPEEACSQMIREAKRTAPSIVYVPHIHLWWEIVGPTLKATFTTLLQTIPSFAPVLLLATSEKPYSALPEEVQELFTHDYGEIFNVQLPDKEERTKFFEDLILKQASKPPVSQKKAVLQALEVLPVAPPPEPRPLTAEEVKRLEEQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLKDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESRKKRGCSSSKYAPSYYHVMPKQNSPPVGDKKPDQEQNEKLKVPCTPVACSTPAQLKRKFHKKSKWHVGTKIKRRKISQAKDNSLNAMNSSSRSDTEDSQHTHAEHTEPGNTDESSVEESDKQNRLESNIDLKNNSSSSNIENELEEPKETTEGTELRKDRIVCRGDASASQVTDIPEDSESKEMDFLRMTLARGSQVEQQELISMEQALAILSQPTPSLVLDHKQLTNILKTVVKKSQKYNIFQLENLYAVISQCIYEHRRDYDKTALVQKMEQAVENFNCSRS
What is the function of this protein?
May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1.  May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters.  May be required for histone hyperacetylation (By similarity).
What are the official names of this protein?
ATPase family AAA domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VID30_YEAST
Sequence: MSEYMDDVDREFINCLFPSYLLQQPVAYDLWILYLQHRKLFHKLKNTNLINADENPTGVGMGRTKLTALTRKEIWSKLMNLGVLGTISFEAVNDDYLIQVYKYFYPDVNDFTLRFGVKDSNKNSVRVMKASSDMRKNAQELLEPVLSEREMALNSNTSLENDRNDDDDDDDDDDDDDDDDDDDDDESDLESLEGEVDTDTDDNNEGDGSDNHEEGGEEGSRGADADVSSAQQRAERVADPWIYQRSRSAINIETESRNLWDTSDKNSGLQYYPPDQSPSSSFSSPRVSSGNDKNDNEATNVLSNSGSKKKNSMIPDIYKILGYFLPSRWQAQPNNSLQLSQDGITHLQPNPDYHSYMTYERSSASSASTRNRLRTSFENSGKVDFAVTWANKSLPDNKLTIFYYEIKVLSVTSTESAENSNIVIGYKLVENELMEATTKKSVSRSSVAGSSSSLGGSNNMSSNRVPSTSFTMEGTQRRDYIYEGGVSAMSLNVDGSINKCQKYGFDLNVFGYCGFDGLITNSTEQSKEYAKPFGRDDVIGCGINFIDGSIFFTKNGIHLGNAFTDLNDLEFVPYVALRPGNSIKTNFGLNEDFVFDIIGYQDKWKSLAYEHICRGRQMDVSIEEFDSDESEEDETENGPEENKSTNVNEDLMDIDQEDGAAGNKDTKKLNDEKDNNLKFLLGEDNRFIDGKLVRPDVNNINNLSVDDGSLPNTLNVMINDYLIHEGLVDVAKGFLKDLQKDAVNVNGQHSESKDVIRHNERQIMKEERMVKIRQELRYLINKGQISKCINYIDNEIPDLLKNNLELVFELKLANYLVMIKKSSSKDDDEIENLILKGQELSNEFIYDTKIPQSLRDRFSGQLSNVSALLAYSNPLVEAPKEISGYLSDEYLQERLFQVSNNTILTFLHKDSECALENVISNTRAMLSTLLEYNAFGSTNSSDPRYYKAINFDEDVLNL
What is the function of this protein?
Required for the adaptation to the presence of glucose in the growth medium; mediates the degradation of enzymes involved in gluconeogenesis when cells are shifted to glucose-containing medium (PubMed:9737955, PubMed:12686616).  Required for proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBP1) (PubMed:9737955, PubMed:12686616, PubMed:22645139, PubMed:28126757).
What are the official names of this protein?
Vacuolar import and degradation protein 30, Glucose-induced degradation protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: BSSR_ECO57
Sequence: MFVDRQRIDLLNRLIDARVDLAAYVQLRKAKGYMSVSESNHLRDNFFKLNRELHDKSLRLNLHLDQEEWSALHHAEEALATAAVCLMSGHHDCPTVITVNADKLENCLMSLTLSIQSLQKHAMLEKA
What is the function of this protein?
Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media.  Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways.  Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway (By similarity).
What are the official names of this protein?
Biofilm regulator BssR.
Protein: APT_ROSS1
Sequence: MTTNLADLIRNIPDFPIPGIQFKDITPLLQNGAAFKEVIDTLAARYEGRALDAIVGIESRGFIFSAPLAYRLGVGMIPIRKPGKLPWETFAVEYDLEYGTNKLEMHRDALAPGARVVVIDDVLATGGTVAAACQMVEMAGAVVEEVAFLIELTFLKGRERLAKYPFFSMIQY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y070_CHLTR
Sequence: MVASISPYYGVSFLEFFLVFFSRLFSGKLFYDHLYIDDIQVIVFFAIAVSCSVVGTFLVLKKMAMYANVVSHTILFGLVCVCLFTHQLIHLSMQALTIAAVSTTLLTGASIHFIRNVFKVAEEASTALVFSLLFSASLLLLVFLTRNAHVGTELVIGNADALAKTDILPIFLVLLINLGISYCFFSSFVCVSFDTIFAFSLGIRIRLVDYLIMLLLSASIVGAFKAVGVLMSLAFLLIPGLIAKLIASSVQEMMVYSMVFGGLAALIAPALSRSILSIYGIGLSTSGLAVGLLLVFYVVMLVFVCSKRAIMLRQKLDK
What is the function of this protein?
Part of an ATP-driven transport system CT_067/CT_068/CT_069/CT_070 for a metal.
What are the official names of this protein?
Probable metal transport system membrane protein CT_070.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS6_BURP1
Sequence: MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDAQGADELTFLDITATSDGRDLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVSMNSSAVANPPLVRDAADKYGSQCIVVAIDAKRVSADGEPPRWEVFTHGGRKGTGLDAVEWARKMAELGAGEILLTSMDRDGTKAGFDLALTRAVSDAVPVPVIASGGVGSLEHLAAGITEGHADAVLAASIFHYGEHTVGEAKRFMAERGIAVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_LAWIP
Sequence: MSLIRSQAYTNAGVNINAGNALISNIKSFVSETNIQGVLSDLGGFGGLFKLNLTQVDNPVLVSSTDGVGTKLKFAFDFNKHDTVGIDLVAMCVNDILVQGARPLFFLDYFATSKLDVDKATQVIYGISEGCKQARCALLGGETAELPGMYTEGEYDLAGFCVGIVDQSKIIDGSSIKVGDTIIGLASSGIHSNGYSLVRQIINQCAIEPDNIIPGSRDTFKQVLLKPTFIYSDIICNLIKDISIKGMVHITGGGFYDNIPRVLPQSVVANIQFSSWDIPPIFYWLQEQGSLSWSEMLQVFNCGIGYVLIIPNDSVTRAMNILKSMEVSAWIIGSIEKQNVGDEQVIITY
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXN4A_MOUSE
Sequence: MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
What are the official names of this protein?
Thioredoxin-like protein 4A, DIM1 protein homolog, Spliceosomal U5 snRNP-specific 15 kDa protein, Thioredoxin-like U5 snRNP protein U5-15kD.
What is the protein family that this protein belongs to?
Belongs to the DIM1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMB_STRPN
Sequence: MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVEVGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTDYFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFEYSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.