PharMolix/UniProtQA huggingface dataset:
Protein: KDPA_SALSV
Sequence: MAAQGFLLIASFLLILLVLAKPLGSGLARLIAAVPLPGVAGIERILWRTLGITDHEMNWRQYLLALLTLNLLGLGILFCLLFWQEWLPLNPQRLPGLSWDLALNTAVSFVTNTNWQAYSGESTLSYFSQMAGLTVQNFLSAATGIAVVFALIRAFTRQNVHTLGNAWQDLVRITLWILFPVALIIALFFIQQGVPQNLSAYQPITTLEGAKQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNLAQMLAIFLIPAALCFAFGEAAGDRRQGRALLWAMSFIFVVCVAVVMWAEVQGNPHLLAAGADSSVNMEGKETRFGVLASSLFAVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKMTALAILVTPMLVLLGSALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKVQPASQGTLATHGALFIGLLIGTVLLVGALTFIPALALGPVAEHFSLP
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EGC_CITJA
Sequence: MGVGTKVLVITTMAICLISSAAYASEGTATFYTPPYVPSACNGYKNDGVMIAAASYAIWNNGAVCNKSFRVKCTGATNQGTPHPCRGGSVLVKIVDLCPAGCQATIDLSQEAFSQIANPDAGKIKIEFNQA
What is the function of this protein?
Might have a systemic role in water and solute homeostasis.  Has no expansin-like activity.
What are the official names of this protein?
EG45-like domain containing protein, Blight-associated protein p12, Plant natriuretic peptide, PNP.
What are the subcellular locations of this protein?
Secreted.
Protein: RR19_TOBAC
Sequence: MTRSLKKNPFVANHLLKKIDKLNTKAEKEIIVTWSRASTIIPTMIGHTIAIHNGKEHLPIYITDSMVGHKLGEFAPTLNFRGHAKSDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: METXA_CHLCH
Sequence: MMCMKALEALVSPQTLFYTSNEPFITEFGATLPELQVAYRMWGRLNADKSNVIVICHALTGSADADDWWEGMFGTGKAFDPSEYCIICSNVLGSCYGTTGPTSPNPATGNRYGADFPLITIRDMVRVQHRLLTALGIERIKLVVGASLGGMQVLEWGFLYPEMAQALMAMGASGRHSAWCIGQSEAQRQAIYADRHWNGGSYAPEQPPNHGLAAARMMAMCSYRSFENYQERFGRTMQQGRQGALFSIESYLHHQGRKLVERFDANTYVTLTKAMDMHDVARGRGEYEEVLRSMTLPIEVLSINSDILYPMEEQEELAELMPNASILYLDEPYGHDAFLIEVEKVNQMVNDFLNKLE
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMB1_MOUSE
Sequence: MEQLTTLPRLGDLGAMEPWALPAWQHWTQGQGCKPGDASPSIAGTPTALQVKGLRFEESSKPEGAHSPGPVGNTDPEATETGLPKLGQQAESPGYSCSGLEEEEAQAYKAKFNIGFGDRPNLELLRALGELQQRCTILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERAQKLQETNMRVVSAPVPRPGSSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRELQARLSLVGKEGPQWLHMRDFDRLLRESQREVLRLQRQIALRNQREPLRPARSPGPTAPSRVGAPAPGAPGEAVLQDDVESPQVVLREPEKQQRVQQLESELCKKRKKCESLEQEARKKQRRCEELELQLRAAQNENARLVEENSRLSGRATEKEQVEWENSELKGQLLGVTQERDSALLKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLQEKQEEVRRLQQAQAEAKREHEGAVQLLESTLDSMQARVRELEGQCRSQTERFSLLAQELQAFRLHPGPLDLLTSALGCSALGDHPPPHCCCSIPQPCQGSGPKDLDLPPGSPGRCTPKSSEPALTTLTGIPRRTAKKAESLSNSSRSESIHNSPKSCPTPEVDTASEVEELEVDSVSLLPAAPESHSGGARIQVFLARYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSDDDLLSTLPRELADSSHSSGPELSFLSGGGGGCSSGGQSSGGRSQPRPEEEAAGDELSLSPPPEGLGEPLAVPYPRHITVLKQLAHSVVLAWELPPERVDLRGFHIFVNGELRQALGPGVPPKAVLENMDLRTGPLHVSVQALTSKGSSDPLRCCLAVGAGAGVVPSQLRIHRLTATSAEIAWVPGNSNLAHAIYLNGEECPPARPSTYWATFCNLRPGTLYQARVEAQIPSQGPWEPGWERPEQRAATLQFTTLPAGLPDAPLDVQAEPGPSPGILMISWLPVTIDAAGTSNGVRVTGYAIYADGQKIMEVASPTAGSVLVEVSQLQLLQACHEVTVRTMSPHGESSDSIPAPVAPALASACQPARMSCLSPRPSPEVRTPLASVSPGLGDTSFPLRHPVPHGTQDFSASLSIEMSKGPQEEPPVPCSQEEAGAAVRSISEEKRAIEPTLGQEGPEPVAPSLAKQEVECTSGDAGPVPCSTQGELTQKKPSIEACHGGDLDSGLKLRSEKEDMSELGVHLVNSLVDHSRNSDLSDIQEEEEEEEEEEEELGSRPCSSQKQVAGNSIRENGAKPQPDPFCETDSDEEILEQILELPLQRLCSKKLFSIPEEEEEEEEEEGLEKPGPSRTSQDPSQPELALLGPGCDSSQPQGPGLCPLSPELSGVREHLEDVLGVVGGNGRRRGGGSPEKLPNRKRPQDPREHCSRLLGNGGPQASARPVPPRERGSLPVIEGTRVGQEPGGRGRPGLSRRCPRGPAPESSLVSCLSPKCLEISIEYDSEDEQEAGSGGVSINSSCYPTDGEAWGTAAVGRPRGPPKVNPGPNAYLRLPAWEKGEPERRGRSAIGRTKEPPSRATETGESRGQDNSGRRGPQRRGARVPRSGTTELAPPRSPQEAPPHQDLPVRVFVALFDYDPVSMSPNPDAGEEELPFKEGQLLKVFGDKDADGFYRGESGGRTGYIPCNMVAEVAVDSPAGRQQLLQRGFLPPNVLTEASGNGPSVYSSAHTPGPPPKPRRSKKVELEGPTQLCPGPPKLIHSAAQKTSRPMVAAFDYNPRENSPNMDVEAELPFRAGDVITVFGNMDDDGFYYGELNGQRGLVPSNFLEGPGPESGSLESGTSQAESQRTRRRRVQC
What are the official names of this protein?
Peripheral-type benzodiazepine receptor-associated protein 1, PRAX-1, Peripheral benzodiazepine receptor-interacting protein, PBR-IP, RIMS-binding protein 1, RIM-BP1, TSPO-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the RIMBP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Preferentially expressed in the mitochondria in the presence of TSPO.
Protein: TSAP1_DANRE
Sequence: MNSLWMGNLEPYMDEDFICRAFAQMGETVVKIRLIRDKITGKNAGYGFVELADDTAVERCLRKVNGKPLPGATPPKRFKLSRSNYGKQGESSTFSLFVSDLTPDVDDGMLYEFFHYHFSSCCSGKIVLDANGHSKCCGFVSFESEREQKRALVDLQGATGLGKKALRLSLASSRVNKKKESSENQIWQYHSDSKNASFINQYYYPQNLSYLSTYDWNYSLDYLNPSQNTTPVDVTQSEQTEDDDLEYPDSEINVTEANETFMAQSEELYSALIGCFFQPPESWDGVTCSASSYLPEPINQYEMEDSCSSNWVTT
What is the function of this protein?
Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins.
What are the official names of this protein?
tRNA selenocysteine 1-associated protein 1, tRNA selenocysteine-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the RRM TRSPAP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GLRX1_VAR67
Sequence: MAEEFVQQRLTNNKVTIFVKFTCPFCRNALDILNKFSFKRGAYEIVDIKEFKPENKLHDYFEQITGGRTVPRIFFGKTSIGGYSDLLEIDNMDALGDILSSIGVLRTC
What is the function of this protein?
Displays thioltransferase and dehydroascorbate reductase activities.
What are the official names of this protein?
Glutaredoxin-1.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: TRP2_RHOPR
Sequence: TSMGFQGVR
What is the function of this protein?
Myoactive peptide.  Increases the amplitude and frequency of spontaneous contractions and tonus of hindgut muscle.
What are the official names of this protein?
Tachykinin-related peptide 2, Rhopr-TRP-2.
What are the subcellular locations of this protein?
Secreted.
Protein: MENC_ECO55
Sequence: MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: MENG_MYCTO
Sequence: MSRAALDKDPRDVASMFDGVARKYDLTNTVLSLGQDRYWRRATRSALRIGPGQKVLDLAAGTAVSTVELTKSGAWCVAADFSVGMLAAGAARKVPKVAGDATRLPFGDDVFDAVTISFGLRNVANQQAALREMARVTRPGGRLLVCEFSTPTNALFATAYKEYLMRALPRVARAVSSNPEAYEYLAESIRAWPDQAVLAHQISRAGWSGVRWRNLTGGIVALHAGYKPGKQTPQ
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RL30_SALSV
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAVRGMVNAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: Y734_YERPA
Sequence: MKLGLVAGMLAVCFSFSSVAMTLKLTPEIDLLVVDGKNMSGSLLKGADSLELNSGMHQILFKVIKPLPTDPLVLYSSPPLIVVFNAHNTRSVAIKLPVINTLRDGHQFSKNPLYQLIGDNGHPLSVRHDVLRQDHLNNSTTLETVMAAYNVGKYNASVPAFAAIPPSPVSAVPGTTIPVAGVNTPHKTASLQGENVTEQMLQYWFLQANPETQKRFLIWAKKQPIH
What are the official names of this protein?
UPF0319 protein YPA_0734.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: TSAD_CLOBK
Sequence: MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVISAVVQEALDEANFTLDDIDAIGVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHISANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGETRDDAAGEAFDKVARAIGLGYPGGPKIDKISKEGNEDAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKADVAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPPFILCTDNAAMIGSAAYFEYIKGRRTSLDINAVPNLKLGER
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACB3_PARDP
Sequence: MPLIRIRGLHRVFGEGAARAHVLRGIDLDIHAGEFVAIVGTSGSGKSTLMNILGLLDRPSAGSYHLAGKDVARLSRDARAGLRNRLFGFVFQQYNLIPTLTALENVELPASHAGAAREARRARAAALLRSLGLGHRLTARPLQMSGGQQQRVSIARALMNGGAVILADEPTGALDAESGRQVMRLLSDLAGRGHTVILITHDTDIAARAGRVIRVGEGRIAGDSGTRAAGPAVPVLPETTGSRSAFLHALREAARSALAAIGASPVRTALTLSGIVIGVASVVAMLAIGRGAQEEFVKRASAIGTNWVVVGSDQDTRMPRRPLTLDDAMALKGLPNVAGVMPGRWEQATVRAGAFSIDTDIIGTDRDFRGVHGWDVVRGSFFSEADERGGSPVLLLGSTVAGTLFPDGRDPTGEFVFVNMSPFLVGGVLESKGLSENGSDRDKVVAMPLRSLESRVYGPGELSVIVVALQDMARLDESNALLREAMIRRHGTEDFWLADAAGAFAAAEADRASQNLLLGAVATISIFVGGIGVMNIMFITVRERTREIGIRSATGAAMRDILVQFLTEATVLSALGGLAGLALAVGIGAVAALGLGMPVVFSVTVALGALAGATAMGAAFGLVPAIRAARLSPVEALASP
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OPGB_ECO55
Sequence: MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNITLFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRRHHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDPKLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVASQCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSSQRFSLFTLTVDTHHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIAAFINKIKASPWFKDTVIVVSSDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNYLGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGSHFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELALSTDWCVSQGQLGGQQIVQHVDKTTWQGKTAFKDTVIDMARYKGNVDTLKIVDNDIRYKADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITAKAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGNILGHSPRKLGIGMVEIKVVEREG
What is the function of this protein?
Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones.
What are the official names of this protein?
Phosphoglycerol transferase I, Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the OpgB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYDND_TREPA
Sequence: MYSAHTPWYDGQVMDYPRRTIACGELRRCHVGTVVVLNGWVHRKRSHGTVSFFNMRDRSGIVQVIVSQEENASLWSTVNRIRLECCLAVEGVVRERPPSMINRALHTGEVEVHARTLYVLSENAVLPFRVDDVVHAHEDIRLKYRYLDLRSQRMQERIALRSRVALAIRQFLSMKGFIEIETPTFICSTPEGARDFVVPSRVCPGRFYALPQSPQLYKQLLMVAGFDRYFQLARCYRDEDARGDRQPEFTQIDLEMSFVSRDDVMRVNEDMLRYVFRTSIGVELPTFFPRLTYAQALDQYGTDKPDMRFKPVLQNADFMGMLGTFTPFEEVVAQGGSIRALVLPGKARCYSRRQIEALESIARAHEAHHLFWLKATGGGLEGGIARFFAGVESEVRRRLSAQDEDLLLFVADCRHRVCCVALGAVRSALIRDESFPEKELFSFVWIVDFPLFEWNPAENKWDPAHHMFSAPQEQYLETLEQDPGSVKGDLYDLVLNGYELASGSIRIHDTQLQKRIFKIVGLDPEEAGEKFGFLTEAFKYGAPPHGGIAHGLDRLVMLMTGSESIRDVIAFPKNTLAASPLDNCPSVLDKRQLDELHLTVHV
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_THEVB
Sequence: MARDFYEILGVSRSADAEELKRAYRRLARKYHPDVNKEPGAEEKFKEINRAYEVLSDPQARANYDRFGEAGVSGVGAAGFSDFGIGDMGGFADIFETFFGGFTTSSRRQQGPTRGEDLRYDLKLEFREAVFGGEKEIRINHLETCKTCQGTGAKPGTRPVTCSTCGGVGQVRRSARTPFGSFTQLTTCPTCGGSGVVIEDRCESCGGQGHIQVSKKLKITIPAGVDNGTRLRVSGEGDAGLRGGPPGDLYVYLFVQPDPEFQREGNNILSRIKISYLQAILGCRISVSTVDGEAELKIPAGTQPGTVLVLEGRGVPRVGNPVARGDHLITVDVEIPTHITHEERELLEKLAKIRGERLGKGGLEGFLGSLFGG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MANE_DICDI
Sequence: MNKTKLIKIIFVIGVWILLSTFIINIYNENFEIVNYNNNSQSLKKIFQLNGDLKDEKLSIFLIPHSHCDSGWLQDYDWYYNHVVQYILSGIVNELNLDKEKKFNWVEIGGWVQNDEATATIDDVITQMTQGHQWLKDTLNYTIEYAWQIDPFGYSSSTPTIFSSMGIKGLIINRVSDDVKSYMKSAKEMEFIWKGSESLGEQSQMLVSTLNVHYDYPKHIDPKKDFSLEERVKGFTKYIKDLSNTRESSILMIPLGDDFRYSNAKNEFSVSKEWLKVIQDNKEKYNIKEIKYATIDEYFIALEDEFMNKLGKTVEENLKTGFSSTLSLYNKDFFPYSTGDLEYWTGYYTTRPLLKRLIRESSLLQKSSDILYTLAIGENSNNQIDINNLQTLSNQLNENRNTIALVQHHDIVTGTSRSFVLNDNFQRLQKSRISNYNIISNSLEYLLNKDNNNNENTDSTNEPFNFENVIDLSNEINNQYSLVFHNTLGWEVNQHVSFRIKVNKNDNQLLESIQLVEAISNKTIQIQIIPIQDDSNCQSIENNYIVFAIINLPPLGLNTYYLSISSNEDSKPNTILSKPKLLKKGNEINFNNNRFKVEFESNGLISKITDKNSNEIKTIEQTFHQYSTKKSGPYIFNVKGGKKHGFLENPDKFIYHDGPLVSQLTMLYGVDDGCNVTSIVVQRIYKNNEIDNSNSKSLITENYIETGYSINGDMNRETTINYKVKDLENDDIFYTDNGLESRKRIYNHDRTVNQNYYPVLGYIKLKETSENNNHQYTVYVDRSVGATSPSDGEMEIMIHRTMDTDDWKGVNWPSKDIGRSDAKLYFNMDLVNNQLQNEKRISLHITNQPIMFVKKHNNQTGYLLKYSPLSNQLPSNIHLQSLLTLKNNTVGLRLFNIHEVDSNTQSTTDTDKSTLFNELEISNFIETGLSFLKLTKNNLIDKYSTRINKKFPVKCGESEYSFINEKPSSIIFSNNGTNNIIDGENKGENNKTIETIQIKPHEIKSFTFNFNFQLDQIIPNNNNYAINKELNNEYIEQSIENQRYEYDFSFFPIKPTFYDDRGKYNRPNHLALILSLSIGTPAGILIIVIALVVIYKKRKNRKTLTSSYSLLNLILKDRADSSP
What are the official names of this protein?
Alpha-mannosidase E.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 38 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SAND_LACM4
Sequence: MKTKITLSGFAGTGKSTVGKRIQEQLNFEFVSVGNYSRQYAMEKYGLTINEFQEQCKAQPELDNEIDEKFRLECNSKENLVIDYRLGFHFIKNAFHVLLKVSDESASKRIRLANRSDEVTSTKAIQQRNQKMRDRFQDNYGVDFTNDKNYDLVIDTDDLTANEVADLIIEHYQKSNAVSKIPSVNFHLWQPCNMRCKFCFATFLDVKQEYVPKGHLPEDEALEVVRKIAAAGFEKITFAGGEPLLCKWLPKLIKTAKQLGMTTMIVTNGSKLTDSFLKENKAYLDWIAVSIDSLDEENNIKIGRAITGKKPLSKAFYYDLIDKIHQYGYGLKINTVVNKVNYKDNLASFIAKAKPKRWKVLQVLPIKGQNDNKIDAFKITDEEYANFLDTHKDVETIVPESNDEIKGSYVMVDPAGRFFDNAAGTHNYSKPILEVGIQEALKTMNYDLDKFLNRGGVYNWNTNKNQDLRKEEVSYE
What is the function of this protein?
The N-terminus of the protein may generate NTP for use by the viperin domain.
What are the official names of this protein?
S-adenosylmethionine-dependent nucleotide dehydratase, SAND, Prokaryotic viperin protein pVip60, pVip60, Putative nucleotide kinase-viperin fusion protein pVip60.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the radical SAM superfamily. Viperin family.
Protein: ISPF_YERE8
Sequence: MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRALLREAYRRILAKGYRLGNLDITIIAQAPKMAPHIPQMRVHLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVALLIKVEQA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: TRMB_CERS4
Sequence: MSDDDAPESLRGAADGPAWRNFYGRRSGKTLRPSQKVYLSEDLGRLRPEGITREENPERRPLDLGALFGGRPVWLEIGFGGGEHMVHMAARNPGIGLIGCEPFVNGVAMLLGKIRAAGVENLLVHPGDVRDLFDVLPEASVSKAFLNYPDPWPKKRHHRRRFVTQGYLGPLARVLAPGATFRVATDIPDYVRQTLEEVPQAGFDLVSESGEAWEDWLSTRYEQKALREGRVPHYMTFRRQG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: SIR5_MACMU
Sequence: MRPLQIVPSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKCFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGIVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDKELGRCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALARHENETVS
What is the function of this protein?
NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins.  Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting.  Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species.  Activates SHMT2 by mediating its desuccinylation.  Modulates ketogenesis through the desuccinylation and activation of HMGCS2.  Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.  Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.
What are the official names of this protein?
NAD-dependent protein deacylase sirtuin-5, mitochondrial, Regulatory protein SIR2 homolog 5, SIR2-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm, cytosol. Nucleus. Note=Mainly mitochondrial. Also present extramitochondrially, with a fraction present in the cytosol and very small amounts also detected in the nucleus.
Protein: TRMD_HAHCH
Sequence: MLIGIRISEVWFGVITLFPEMLKSVTDFGVVGKAIKQSSIEVCTWNPRDYATDNYRTVDDRPYGGGPGMLMKVGPLEAALNAAKSVAPAGSKVVYLSPQGRRLDQALARSALSVPGLILLCGRYEGIDERLIEDEVDEEWSLGDFVLSGGEIAAMAIIDSVSRLAPGVLGHNESAEQDSFENSLLDCPHYTRPEIYRDKRVPEVLLSGNHEKIRRWRLEQSLLRTLQRRPDLLEQRELSEEEAQIIQELRRGQLISET
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_ECOL5
Sequence: MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RR16_HORVU
Sequence: MVKLRLKRCGRKQQAVYRIVAIDVRSRREGRDLRKVGFYDPIKNQTCLNVPAILYFLEKGAQPTRTVYDILRKAEFFKEKERTLS
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TXB5A_SCOMO
Sequence: RRVFTLTFLFLAAEAFHLSDRIETRESETGKGLATCKKDSICAYLQQNARGVTPAHMCECPGEQTCPLSWDPDDGKTLTRGDEQYKFCSSPPQALHECKEKELVFTSKFEYEANSNPRKFLSYAGYIHCACPIGFSYHLTRRTNSTTEGQDLETVYFSCEEYKTCGTNDTCHIISESSEAFMIYKMCNCDEDLKCPTDPEAAFRTDHIEQVLDYNLYNMQCQ
What are the official names of this protein?
U-scoloptoxin(11)-Sm5a, U-SLPTX(11)-Sm5a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-11 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LCL2_AJECG
Sequence: MVHIFTSILLGLLLLATGTRAQFQFFEQMFGGGQQQQQHDSREQNVPSDSDWYQRTYDNARCSNYLCPGTLACVAVPHHCPCQHPAVEDKFELGDGSAICVSKGGFKFGEAARKVELARKGLL
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.