PharMolix/UniProtQA huggingface dataset:
Protein: AI3_DEBHA
Sequence: MKQMSYVTRWLYSTSHKDIGMTYLGFGMLSAMMGTGMSVMMRMELSNGNSQFFHGNNQAFNVMMSGHALLMMFFFIMPVWMGAFGNFFLPMLMGAADMAFARLNNISFWCLPPALVCMVCSVLMEQGAGTGFTTYPPLSSMSAHSGPSVDLAMFAMHLTSMSSLLGAMNFMVTVLNMRTMGLHMVNMPLFAWAMFLTAMLLLLSLPVLTAAVTLLLMDRNFNTGFYEVGAGGDPVTYEHLFWFFGHPEVYILMMPGFGVMSHMVSTYSKKPMFGEMGMLYAMGSIGFLGFLVWSHHMFVVGLDIDSRAYFTSATMVIAVPTGIKIFSWLATIYGGELRLGVPMLFALGFLFLFTMGGLTGVMTSNASMDVAFHDRIFIYYVSFFLYTLYNMYNNYTNNNTAHKGRHCANASYNNDINNLVSFMDKNEYIKMFWVGLMDGDGSMQVNHWRKKNLQYRLIMKTSNLESNYNMLMLMAKVMGGTVRISKKKDNVMWVVDSKESIKDMMKMFDKYPLLTSRKMCQINFMKKCMKLNYMPAEGGYPREAGTDWYLLNRNYKYNDQLNMINTFNLKLKNKSFMNALPEGHGMHHMVKHSEYFKCWLSGFMEAEGCFSIRLNKSNSFSMGQNDDFYLMEEIKQFFNATNSVRNSYKNFYCLEIYKRIMLNNIITHCSNYPLLGEKKESLMKFLK
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.
What are the official names of this protein?
Probable intron-encoded endonuclease aI3.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Multi-pass membrane protein.
Protein: ARLY_SHEDO
Sequence: MALWGGRFQGETSALFKLFNDSLPVDYRLFEQDVIGSIAWADAIASVGVISAAECTELKAALKELLAEVGDDPQVIISTGAEDIHSFVEQKLIAKVGDLGKKLHTGRSRNDQVATDLKLWCKREGAALLARLNTLRSELIALAEREVDAVMPGYTHLQRAQPITFGHWCLAYVEMFERDLSRLTDALKRADTCPLGSGALAGTAYPIDRHALASALNFARPTLNSLDSVSDRDHVVELCSSASISMMHLSRMAEDLIFFNSGEANFISLADDVTSGSSLMPQKKNPDALELIRGKTGRVYGSLMGILTTMKALPLAYNKDMQEDKEGLFDVVDSWAICLDMAALVLSGLKVNREPALQAAQQGYANATELADYLVAKGMPFREAHHVVGEVVVFAITQQQPIEDLTLTQLQAFAKEISDDVYPNLTIAACLSKRNVLGGTAVNQVSAAIAVKKQD
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHB_BORBU
Sequence: MIKDEFLIKSWYIPLDFFSADDEGRTELPTDQKKQKAREEGRVLKSTEINTAVSLLLLFALFFFMLSYFALDLIAVFKEQAIKLPEVMRMSVYTMGFAYIRSIMGYVVLFFFASLAVNFFVNIIQVGFFITFKSLEPRWDKISFNFSRWAKNSFFSAGAFFNLFKSLLKVVIICLIYYFIIENNIGKISKLSEYTLQSGISIVLVIAYKICFFSVMFLAIVGVFDYLFQRSQYIESLKMTKEEVKQERKEMEGDPLLRSRIKERMRVILSTNLRVAIPQADVVITNPEHFAVAIKWDSETMLAPKVLAKGQDEIALTIKKIARENNVPLMENKLLARALYANVKVNEEIPREYWEIVSKILVRVYSITKKFN
What is the function of this protein?
Required for formation of the rod structure in the basal body of the flagellar apparatus.  Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity).
What are the official names of this protein?
Flagellar biosynthetic protein FlhB.
What is the protein family that this protein belongs to?
Belongs to the type III secretion exporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TSAD_NEIG2
Sequence: MLVLGIESSCDETGVALYDTERGLRSHCLHTQMAMHAEYGGVVPELASRDHIRRLVPLTEGCLAQAGASYGDIDAVAFTQGPGLGGALLAGSSYANALALALDKPVIPVHHLEGHLLSPLLAEEKPDFPFVALLVSGGHTQIMAVRGIGDYELLGESVDDAAGEAFDKTAKLLGLPYPGGAKLSELAESGRPEAFVFPRPMIHSDDLQMSFSGLKTAVLTAVEKVREANGSETIPEQTRNNICRAFQDAVVEVLEAKVKKALLQTGFRTVVVAGGVGANRKLRETFGNMTVQIPTPKGKPKHPSEKVSVFFPPMAYCTDNGAMIAFAGAMHLGKGREVGAFNVRPRWSLSEIVK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_BUCBP
Sequence: MAAKIKKNDQVIVLIGKDKGKIGIVRKVIAKSKVIVEGVNIVKKHTKPSPSQNKKGGIVEQESSINISNIAILNPTTKKSDRIGFRVKNGKKVRFFKSNNTICN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: BP37_RHYMA
Sequence: ALFEESTVSAEPR
What are the official names of this protein?
Brain peptide 37F3.
Protein: ZN394_MOUSE
Sequence: MAAGSGVVPPPLGAGLCTVKVEEDSPGNQESSGSGDWQNPETSRKQFRQLRYQEVAGPEEALSRLWELCRRWLRPELLSKEQIMELLVLEQFLTILPQELQAYVRDHSPESGEEAAALARTLQRALDRASPQGFMTFKDVAESLTWEEWEQLAAARKGFCEESTKDAGSTVVPGLETRTVNTDVILKQEILKEAEPQAWLQEVSQGMVPALTKCGDPSEDWEEKLPKAAVLLQLQGSEEQGRTAIPLLIGVSREERDSKNNESENSGSSVLGQHIQTAEGLGTNSQCGDDHKQGFHVKCHSVKPHSSVDSAVGLLETQRQFQEDKPYKCDSCEKGFRQRSDLFKHQRIHTGEKPYQCQECGKRFSQSAALVKHQRTHTGEKPYACPECGECFRQSSHLSRHQRTHASEKYYKCEECGEIVHVSSLFRHQRLHRGERPYKCGDCEKSFRQRSDLFKHQRTHTGEKPYACVVCGRRFSQSATLIKHQRTHTGEKPYKCFQCGERFRQSTHLVRHQRIHQNSVS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 394, Zinc finger protein 94, Zfp-94, Zinc finger protein with KRAB and SCAN domains 14.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPH1_NEMVE
Sequence: MADSVEQSSVTTKRISAKGARKRFVGTKSASGKHSQGVDRVGSAAHRPVNQIPEEILKDTKLQEALPENYNFEIHKTIWRIQQVKAKRVALQFPEGLLLFACTIADILESFTGCETVIMGDVTYGACCVDDYSARALGCDLLVHYGHSCLVPIDATAGIKMLYVFVDIKIDTAHFVESVRFNLGAGSCLALVSTIQFVAALQAASNELSKDYQVEIPQCKPLSPGEILGCTAPMLKDKDAVIYLGDGRFHLEAVMIANPAIQAYRYDPYDKTFSKEYYDIDKMHEARQTAIKQASLASKYGLILGTLGRQGSPKVLQTLEKQLQSLNMDYIIVLLSEVFPDKLKLFKDVDAWVQVACPRLSIDWGTAFPKPLLSPYEASVALQSVAWQQSYPMDFYAYSSLGGWTPNNESNRPTPANRRKKNLHTEVIIDNVSDSKPVIKESECGSGETCCGKCTKETDKHSSTP
What is the function of this protein?
Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (By similarity).  Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1, Diphthamide biosynthesis protein 1, Diphtheria toxin resistance protein 1, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH1 subfamily.
Protein: INP5K_MOUSE
Sequence: MQHGDRNTPGYREGIMSAVSLRRPSAPKGFALSVHVVTWNVASAAPTVDLSDLLQLNNQDLNLDIYIIGLQEMNFGIISLLSDAAFEDPWSSLFMDMLSPLNFVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSTPTGLYGYWGNKGGVNVCLKLYGYYVSIINCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRIEDFGLLFVQESITRKYYKELWEKDQLFIAKKNDQLLREFQEGPLLFPPTYKFDRHSNNYDTSEKKRKPAWTDRILWRLKRQPSQASPLASSVPTSYFLLTLKNYVSHMAYSISDHKPVTGTFDLELNPLMSVPLITMMPEHLWTMENDMLISYTSTPEFLSSSWDWIGLYKVGMRHINDYVAYVWVGDNQVSYGNNPNQVYINISAIPDTEDQFLLCYYSNNLHSVVGISQPFKIPIRSFLREDTLYEPEPQI
What is the function of this protein?
Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate.  Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate (By similarity).  Negatively regulates assembly of the actin cytoskeleton.  Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle (PubMed:22247557, PubMed:22751929).
What are the official names of this protein?
Inositol polyphosphate 5-phosphatase K, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase, Phosphatidylinositol-4,5-bisphosphate 5-phosphatase, Skeletal muscle and kidney-enriched inositol phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Cytoplasm. Note=Following stimulation with EGF, translocates to membrane ruffles.
Protein: TRMB_CAMJ8
Sequence: MPNFKSKKIKEINLPYSKDDVEFLWLAKNDNVSLIYTKVQEESFFLQIKKAQNGFVIKGDKHTKPSKIGYLQKALKIFKEGFCEDIINEAFGLKNNALIEKTPFIVDNFDELLSKLQGKIYIEIGFGSGRHLLYQAKENPNVLILGVEIYNPALTQVAKLAKVQNVNNILLIQSDARLLLSVLKSKSVEKIFLHFPVPWDKKPHRRVIGKDFCKECARVLTQNGRFELRTDSFEYFNFTLEQFLTFPAPKFSLRKNENLEISSKYEDRWKKQEKNIYDLWVWNFNQECKNYELNEFNLSSVEFSKEDLKKIEQNFKNITIKKDDFFLHFESIYKQDENLLLKVAFGAFNKPEHCYLHLDKTIDFVFKEPFKIQENIKAINELKEILKVQFKI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RL36_METS4
Sequence: MKIRNSLKSLRGRHRDNQLVRRKGRVYVINKTQKRYKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TAXB1_BOVIN
Sequence: MTSFQEVPLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSAVNCELAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRAASPVEELLTMEDEGNSDMLVVTTKAGLLELKIEKTMKEKEELLKLIAVLEKETTQLREQVGRMERELNHEKERGDQLQAEQKALTKVSQSLKMENEEFKKRYNDVTSKALQLEEDIVSVTHKAIEKETELDSLKDKLKKAQCEREQLECQLKTEKDEKELYKVHLKNTEIENTKLVSEVQTLKNLDGNKENMITHFKEEISRLQFSLAEKENLQRTFLLTTSSKEDTFILKEQLRKAEEQIQATRQEAVFLAKELSDAVNVRDKTMADLHTAHLENEKVKKQLTDALAELKLSAVNKDQEKTDTLEHELRREVEDLKLRLQMAADHYKEKFKECQRLQKQINKLSDQSANSNSVFTKKIGSQQKVNDASINTDPAATASTVDVKPLPSTAETDFDNLTKGQVSEMTKEIADKTEKYNKCKQLLQDEKTKCNKYADELAKMELKWKEQVKIAENIKLELAEVVDNYKLQLAEKEKEISGLTSYWENLSREKEHKRSVENQAERKLEGQNSQSPHQISQCLKTSSEKSGHVPAVSNTQPVLQYGNPYATPETRDGADGAFYPDEIQRPPVRVPSWGLEDNVVCSQPARNLSRPDGLEDPEDSKEDEKVPTAPDPPSQHLRGHGTGFCFDPSFDVQKKCPLCELMFPPNYDQSKFEEHVESHWKVCPMCSEQFPPDYDQQVFERHVQTHFDQNVLNFD
What is the function of this protein?
Ubiquitin-binding adapter that participates in inflammatory, antiviral and innate immune processes as well as selective autophagy regulation.  Plays a key role in the negative regulation of NF-kappa-B and IRF3 signalings by acting as an adapter for the ubiquitin-editing enzyme A20/TNFAIP3 to bind and inactivate its substrates.  Disrupts the interactions between the E3 ubiquitin ligase TRAF3 and TBK1/IKBKE to attenuate 'Lys63'-linked polyubiquitination of TBK1 and thereby IFN-beta production.  Recruits also A20/TNFAIP3 to ubiquitinated signaling proteins TRAF6 and RIPK1, leading to their deubiquitination and disruption of IL-1 and TNF-induced NF-kappa-B signaling pathways.  Inhibits virus-induced apoptosis by inducing the 'Lys-48'-linked polyubiquitination and degradation of MAVS via recruitment of the E3 ligase ITCH, thereby attenuating MAVS-mediated apoptosis signaling.  As a macroautophagy/autophagy receptor, facilitates the xenophagic clearance of pathogenic bacteria such as Salmonella typhimurium and Mycobacterium tuberculosis.  Upon NBR1 recruitment to the SQSTM1-ubiquitin condensates, acts as the major recruiter of RB1CC1 to these ubiquitin condensates to promote their autophagic degradation.
What are the official names of this protein?
Tax1-binding protein 1 homolog.
Protein: GUF1_EMENI
Sequence: MRGCLQLARWLSAAPNWPASSLLKAPGSSFATRLFTTTSSYKAKGPSKVPMTDLEARISAIPIERYRNFCIVAHVDHGKSTLSDRLLELTGTIKPGMNKQVLDKLDVERERGITVKAQTCTMIYNHKGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGIQAQTVANFYLAFSQGLELIPVINKVDLPSAEPERALEQLEQSFELDTEDAVLVSAKTGLNVEQLLPTVVEKIPAPIGDCKRPLRMLLVDSWYDSYKGVICLVRVFDGEVRAGQQVVSFATGIKYYVGEVGIQYPLETPQTVLRAGQVGYIFFNPGMKRSKEAKIGDTFTTVGSEKAVQPLPGFEEPKAMVFVAAYPVDADHFEHLEDSINQLVLNDRSITVQKESSEALGAGFRLGFLGTLHCSVFEDRLRQEHGASIIITPPSVPVKVVWKDGKEDIITNPNRFPDEDDVRMKVAELQEPYVMATLTFPDEYLGTVIELCEANRGEQKSLEYFTPTQVILKYELPLAQLVDDFFGKLKGGTKGYASLDYEESGWKPSNIVKLQLLVNKAPVDAVARLVHYSQTDRLGRQWVTKFKEHVDRQLFEIIIQAAVGKKIVARETVKPYRKDVLAKLHASDVSRRRKLLEKQKEGRKRLRAVGNVVIEHKAFQAFLAK
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor guf1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase guf1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: IGF1A_CYPCA
Sequence: MSSGHFFQGHWCDVFKCTMRCLSCTHTLSLVLCVLALTPATLEAGPETLCGAELVDTLQFVCGDRGFYFSKPTGYGPSSRRSHNRGIVDECCFQSCELRRLEMYCAPVKPGKTPRSLRAQRHTDSPRTPKKPISGHSHSSCKEVHQKNSSRGNTGGRNYRM
What is the function of this protein?
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.  Acts as a ligand for IGF1R.  Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways.  Binds to integrins.  Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.
What are the official names of this protein?
Insulin-like growth factor I, adult form.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRG_ACIAD
Sequence: MTHFIFVTGGVVSSLGKGISAASVAALLEARGLKVTMVKMDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGYYERFLRRAKMTKLNNFTSGRVYQDVLNKERRGDYLGGTVQVIPHITDNIKERVLAAGEGYDVAIVEIGGTVGDIESLPFMESVRQLMVELGHKRTMLMHLTLLPYIRSAAELKTKPTQHSVKELLSIGIQPDILICRTEHDVDADTKRKIALFTNVEARAVVVCKDAKTIYQIPRNFYEQKVDDLICERFGYNDLPQADLSDWDQVCEALFNPEYIVRVAMVGKYVELPDAYKSVNEALLHAGIQNRVKVQIDYVDAETLETQDISILSTADAILVPGGFGERGTEGKMLAIKYAREQGIPFLGICLGMQLAVIEYARNVAGLAEATSTEFNRSTKFPIIGLITEWLDERGELQQRSVESDLGGTMRLGAQKSELVEGTKTRQVYGKAEIVERHRHRYEMNDRFIEPIEKAGMKISGYSTAQHLVETVEIPEHPWFIAVQFHPEFTSSPRDGHPLFASFIDAAKKQHLKTK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: LPXA_CROS8
Sequence: MIDKTAFIHPTAIVEEGAVIGANAHIGPFCIVGPDVKIGEGTVLKSHVVVNGHTTIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTAQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSKEALHAIRNAYKLLYRSGKTLDEVKPEIAEIAAKHPEVQPFYDFFARSTRGLIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RABP2_XENLA
Sequence: MPNFSGHWKMKQSENFEEMLKALGVNLMLRKIAVAAASKPAVEIKQEGETFYIKTSTTVRTTEINFKIGEEFDEQTVDGRPCKSLAKWVSENKMACEQKLLKGDGPKTAWTREMTNDGELILTMTADDVVCTRIYIRD
What is the function of this protein?
Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.
What are the official names of this protein?
Cellular retinoic acid-binding protein 2, Cellular retinoic acid-binding protein, CRABP, xCRABP, xCRABP-b.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA20_PARTE
Sequence: MFKNSFQSGFLSILYSIGSKPLQIWDKQIKNGHIKRITDQDIQSSVLEIMGTNVSTNFITAPADPKETLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDEGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRIYFSDRLYSEEELPPEFKLFLPIQKQG
What is the function of this protein?
Cilium- and flagellum-specific protein required for axonemal structure organization and motility.  May also play a role in cortical organization of basal body.
What are the official names of this protein?
Cilia- and flagella-associated protein 20, Bug22p.
What is the protein family that this protein belongs to?
Belongs to the CFAP20 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Note=Localizes preferentially in the terminal plate of the basal body and the transition zone of the cilium as well as in the vicinity of the outer doublets of axoneme and between the axoneme and the cell membrane.
Protein: MED9_HUMAN
Sequence: MASAGVAAGRQAEDVLPPTSDQPLPDTKPLPPPQPPPVPAPQPQQSPAPRPQSPARAREEENYSFLPLVHNIIKCMDKDSPEVHQDLNALKSKFQEMRKLISTMPGIHLSPEQQQQQLQSLREQVRTKNELLQKYKSLCMFEIPKE
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 9, Mediator complex subunit 9.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 9 family.
Protein: NA124_ANEVI
Sequence: MMNRLLVFLMLGAAFMLVVSAIDQDANEDINKRGIPCLCDSDGPSVRGNTLSGIIWLAGCPSGWHNCKKHGPTIGWCCKQ
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation during signal transduction (PubMed:19609479).  Has a strong effect on crustaceans and insects and a weaker effect on mammals (By similarity).  It strongly inhibits D. melanogaster sodium channel (DmNav1) (PubMed:19609479).  It strongly affects the heart sodium channels (Nav1. 5/SCN5A) and weakly inhibits the brain sodium channel Nav1. 2/SCN2A (By similarity).  In vivo, when released into the medium, this recombinant toxin induces impaired swimming, paralysis and death of the crustacean A. nauplii within several hours (PubMed:22048953).  Its effect on zebrafish (D. rerio) larvae is much faster, since it induces paralysis or strong convulsion and impaired swimming, within 10 minutes (PubMed:22048953).
What are the official names of this protein?
Delta-actitoxin-Avd1e 1, Delta-AITX-Avd1e 1, Av2, Neurotoxin 2, Toxin 2-4, Toxin 2c5.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Note=In nematocyst, is associated with the tubule prior to discharge.
Protein: AROB_STRA3
Sequence: MQVEVDLPNHSYHIKIEEGCFSEAGDWVSHLWQKQMITIITDSNVEILYGESLVNQLKKQGFTVHVFSFAAGEASKTLEVANRIYGFLAKHHMTRSDGIIALGGGVVGDLAAFVASTYMRGIHFLQIPTSLTAQVDSSIGGKTGVNTSFAKNMVGTFAQPDGVLIDPVTLKTLGNRELVEGMGEVIKYGLIDDIKLWHILEEMDGTIDSILDSALAIIYHSCQVKRKHVLADQYDKGLRMHLNFGHTIGHAIEVHAGYGEIMHGEAVAIGMIQLSRVAERKNLMPRGISQDIYNMCLKFGLPVHYAEWDKDVLFDILSHDKKASGQFIKIVILPQLGSATVHQIPLEEMRDYLEK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOHJ_ECOLI
Sequence: MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAVSTLVVFLVVSWSSQLVHGERKVVGQKGSEE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENGB_ANAMM
Sequence: MLSKCRFVAGVQDKHSLPDFQVPEVAFAGRSNVGKSSLINAVTKNKKGARVSSNPGSTRQINFYLNEGALALVDLPGYGYSKASKESASSYMSLVEHYLLTREALHRLVLLIDSKVGLKEVDMDFISWLEERCIHYSLVLTKIDRLACTEFNDVLSAVQSRVKGCCMLLHPIIGTSSKSGKGIKELVHEVSKCVKEWPGGRDVRA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PCP_MYCBO
Sequence: MSKVLVTGFGPYGVTPVNPAQLTAEELDGRTIAGATVISRIVPNTFFESIAAAQQAIAEIEPALVIMLGEYPGRSMITVERLAQNVNDCGRYGLADCAGRVLVGEPTDPAGPVAYHATVPVRAMVLAMRKAGVPADVSDAAGTFVCNHLMYGVLHHLAQKGLPVRAGWIHLPCLPSVAALDHNLGVPSMSVQTAVAGVTAGIEAAIRQSADIREPIPSRLQI
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_THEP1
Sequence: MVRVKICGITNLEDALFSVESGADAVGFVFYPKSKRYISPEDARRISVELPPFVFRVGVFVNEEPEKILDVASYVQLNAVQLHGEEPIELCRKIAERILVIKAVGISNERDIERALNYREFPVLLDTKTPEYGGSGKTFDWSLILPYRDQFRYLVLSGGLNPDNVRSAIDMVRPFAVDVSSGVEAFPGKKDHDSIKTFIKNAKGL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: MMR1_YEAST
Sequence: MNSPTMKSEQLTPKLSPMSFCLDDQRNAGSFQNLLNSPTKLKLDTGPIGNSLLYPTSLSKLSELSRGGRSKQRRGSDTMRSVSPIRFQFLNNTPKMLKPEYLSQTTSNLPLLSALLKNSKKTTSEGQNSNPDPLNIEKNIIKQSIKDKLEQLRSSESVAQVQKKERNPPSFEAKVCAEEPILRKNAEGLLPSYVPVPATPLEDPENHGVRKVEDKGLRVVSGGSTQCLSTEVNELPKDLNLDNLPTDNNGFVQYGLKGNNNNNRYSFISSTSTDYEPEWCDGQQHISMQMASMANAEEANSREKSNLDIKIKQLELEITELKLQNEKLVHSMTTNRYIEERFMLEVMKDPSIQAQRSQRDIERKVKQLEKKFFNCKKVLKKLTESSAVVATSTSKTEGNSARIPCPKTRLARVSVLDLKKIEEQPDSSSGTSSEEDHLTNDDTDANTSEDLNVAFEEEPTSAISTTASVQSGESKRGFQLNLPVQVEKKEK
What is the function of this protein?
Involved in the guiding of mitochondrial tubules to the bud tip during cell division.
What are the official names of this protein?
Mitochondrial MYO2 receptor-related protein 1.
What are the subcellular locations of this protein?
Bud tip. Bud neck. Mitochondrion outer membrane; Peripheral membrane protein.