PharMolix/UniProtQA huggingface dataset:
Protein: AT10B_MOUSE
Sequence: MTCSLDFSWLRWKWRTQDGFSQSPSETTPLLSPETDRQSHNTAEQRVVYPNNSMCHQDWKKVCRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITIFPLATVLLIIMVKDGIEDFKRYCFDREMNSASIQIYERKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEHFHSTIVCEKPNNHLSKFKGYMEHPDQTRTGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGTFKEHPPFDVPDADGNFLSLALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGSEYCHQENAKRLEMPKELDSDGEEWTQYQCLSFPPRWAQGSTTMRSQGGAQPLRRCHSARVPIQSHCRQRSVGRWETSQPPVAFSSSIEKDVTPDKNLLSKVRDAALWLETSDTRPAKPSHSTTASIADFFLALTICNSVMVSTTTEPRKRVTTPPANKALGTSLEKIQQLFQRLKLLSLSQSFSSTAPSDTDLGESLGPNLPTIDSDEKDDTSVCSGDCSTDGGYRSSTWEQGDILGSESGTSLEEGLEAPTLSQDEPELCYEAESPDEAALVHAARAYSFTLVSRTPEQVTVRLPQGICLTFDLLFTLGFDSVRKRMSVVVRHPLTDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKRFHEPQQPARKLCGHRIPPKMPSVNSGAMAPEIGLVIDGKTLNAIFQGKLENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLMYFVVSLIYNATCVTCNSPTNPYWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKAQKIDKLPIDKRNLEIQNWRSKQRPAPASASASASAPATGTVHTRPPCHPVPPEAQQNFGASTSKSSGPPRQKHVEDRVLQDPRCSREHSRDDTCTVDTLAKLSSGECLLDPNRTVAPTAYSRGQKDVSRHSSKGSHRRSQSSLTI
What is the function of this protein?
Catalytic component of a P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of glucosylceramide (GlcCer) from the outer to the inner leaflet of lysosome membranes (By similarity).  Plays an important role in the maintenance of lysosome membrane integrity and function in cortical neurons (PubMed:32172343).
What are the official names of this protein?
Phospholipid-transporting ATPase VB.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B.
Protein: P2C37_ORYSJ
Sequence: MVMASAGVNMPGGDGDHPPAAAQECHRLRRRRYVPAAAAASEDGDNSSNGGGEKRSLPASSASPSPSPTSSAASSDCSSDRDDDGCSSTAGAAARRLPLPSGASTAAAVWPVAFGSVSLAGRMRDMEDAVSLRPSFCTWLDGSPMHFFAVFDGHGGPHVSALCREQMHVIVAEEMVAEAAALRQRQPAAMEEEEEERAVAGGAVAELRPGGRAGGGGVRVRARHRAGVPCPLSGQTGAIIGSTAVVALLVRDRLVVSNCGDSRAVLCRAGDPLPLSSDHKGLNPSLSWRGTRVALARGTWGDKTGQSVGPAALLLSGGAHPDRPDEKARIEAVGGRVVYLNGPRVRGILAMSRALGDKYLKPEVICEPDITITVRTVDDECLILASDGMWDVISNETASDVARQCLEDGSPTSGRRAARSGEAASSSAGAPAAAVGQESEPRCYRAAALLARLALGRESSDNISVVVIDLKGRG
What are the official names of this protein?
Probable protein phosphatase 2C 37, OsPP2C37.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: KCTD1_RAT
Sequence: MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETSRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELRRTPRVPSVIRIKQEPLD
What is the function of this protein?
May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD1, Vitamin A-deficient testicular protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_NEIG1
Sequence: MARLREFYKETVVPELVKQFGYKSVMEVPRIEKITLNMGVGEAVADKKVMEHAVSDLERIAGQRPVVTVARKSIAGFKIRDNYPVGCKVTLRRDQMFEFLDRLITIALPRVRDFRGVSGKSFDGRGNYNMGVREQIIFPEIEYDKIDALRGLNITITTTAKTDEEAKALLSLFKFPFKG
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RS3A_DICDI
Sequence: MADKKKKGSKKGGKKVDPFTRKEWYVVRAPTQFFKSPADNKVGFTPVNRTQGTKLASDGLKGRVYEVSLADMKDDESQVFRKIKLRAEEVEGRNVLTNFYGMDLTSDKLRSLIHKWSTLIECFVDVKTTDGYFLRVFAICFTKKGESQKKKTSYAKTSRVKAIRKKMVDILTETVSSNDLKTVVDYLIGVSLNGVTTNASGFAPTLAEKIRIEGSSIFPIHNVFIRKVKVLKTPKVDAAKLSELYASSATSTIAPTEEVGTAVERTEETTTTA
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_BURO0
Sequence: MNLNATLFAQMVVFLVLAWFTMKFVWPPLINALDERSKKIADGLAAAEKGKAELDAAHKRVDQELAQARNDGQQRIADAEKRAQAVAEEIKANAQAEAARIVAQAKAEAEQQIVKAREALRGEVAALAVKGAEQILKREVDQTAHAQLLNQLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
Protein: SYY_FUSNN
Sequence: MEGKMANVYDVLKERGYLKQLTHEEEIREILGKEKVTFYIGFDPTADSLHVGHFIAMMFMAHMQQHGHRPIALAGGGTGMIGDPSGRSDMRTMMTVEMIDHNVECIKKQMQKFIDFSEDKAILANNADWLRNLNYIEFLRDVGEHFSVNRMLAAECYKSRMENGLSFLEFNYMIMQAYDFYILNHKYNCTMQLGGDDQWSNMIAGVELLRRKDRKPAYAMTCTLLTNSEGKKMGKTAKGALWLDPEKTTPYEFYQYWRNIDDQDVEKCLALLTFLPMDEVRRLGALKDAEINEAKKVLAYEVTKIIHGEEEATKAKEATEALFGSGNNLDNAPKIEVTDEDFSKELLDVLVDRKIIKTKSEGRRLIEQNGMSLNDEKIKDVKFTLNDNTLGLLKLGKKKFYNIVKK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOSB_LYSSC
Sequence: MTVQSINHLLFSVSDLEKSIAFYENVFGAKLLVKGNSTAYFDVNGLWLALNVEKDIPRNDIQYSYTHIAFTISEDEFDKMYDKLVQLKVLILDGRQRDERDKKSIYFTDPDGHKFEFHTGTLQDRLDYYKKEKLHMEFFNH
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y728_ENTFA
Sequence: MKNYPVKKNDVIEVEIIDLTHEGLGVAKVDHYPLFIENALPGEKLEIKVLKTGKSFGYGKVLTVLKSSEQRVPVKDENFTKVGISPLQHLAYGAQLSFKTQQVENVMQRVAKLQEVPVLPTIGMNDPWHYRNKAQIPVRKIDNQLQTGFFRKNSHDLIPMEHFYIQDPEIDAAIVKIRDIMRKYSVKPYNESDNTGNLRHIVVRRGYHTGEMMVVLITRTPKLFPISKIVPDILEAIPEVVSIVQNVNPKRTNVIFGDETILLHGSEKITDTIFDLKFEISARSFYQVNPQQTEVMYQKVKEYAALTGNEIVVDAYCGIGTIGLTLAQDAKQVYGIEVIEEAVKDAENNAKLNNIENATFTAGLAEELLPKLVENGLQPDVVVVDPPRKGLDGQLVNTLIETQPERIVYVSCNPATLARDIALLTEGGYEAKEIQPVDNFPQTTHIESVTLLTKAVD
What are the official names of this protein?
Uncharacterized RNA methyltransferase EF_0728.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: COBS_ECO27
Sequence: MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLLGAISGLVFMVLQAWCGVPLAALFSVLVLALMTGGFHLDGLADTCDGVFSARSRDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELTLRGEPILASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQLLKRTLGGQTGDTLGAAIELGELVFLLALL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL40B_CANAL
Sequence: MIEPSLKALASKYNCEKSICRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L40-B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: RNPA_BACCZ
Sequence: MKKKHRIKKNDEFQTVFQKGKSNANRQFVVYQLDKEEQPNFRIGLSVSKKIGNAVVRNRIKRMIRQSITELKDEIDSGKDFVIIARKPCAEMTYEELKKSLIHVFKRSGMKRIKSSVRK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: IF1_CORGB
Sequence: MAKEGAIEVEGRIVEPLPNAMFRVELDNGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLTRGRIVYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOX9_CHICK
Sequence: MNLLDPFMKMTEEQDKCISDAPSPTMSDDSAGSPCPSGSGSDTENTRPQENTFPKGDPDLKKESDEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQSEQEEGSEQTHISPNAIFKALQADSPQSSSSISEVHSPGEHSGQSQGPPTPPTTPKTDAQQPGKQDLKREGRPLAEGGRQPPHIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVPATHGQVTTYSGTYGISSSASSPAGAGHAWMAKQQPQPPQPPAQPPAQHTLPALSGEQGPAQQRPHIKTEQLSPSHYSEQQQHSPQQQQQQQQQLGYGSFNLQHYGSSYPPITRSQYDYTEHQNSGSYYSHAAGQSGGLYSTFTYMNPTQRPMYTPIADTSGVPSIPQTHSPQHWEQPVYTQLTRP
What is the function of this protein?
Transcription factor that plays a key role in chondrocytes differentiation and skeletal development (PubMed:10340758, PubMed:9858536).  Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including COL2A1 (PubMed:10340758, PubMed:9858536).  Plays a central role in successive steps of chondrocyte differentiation.  Absolutely required for precartilaginous condensation, the first step in chondrogenesis during which skeletal progenitors differentiate into prechondrocytes (By similarity).  Together with SOX5 and SOX6, required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes, the second step in chondrogenesis (By similarity).  Later, required to direct hypertrophic maturation and block osteoblast differentiation of growth plate chondrocytes: maintains chondrocyte columnar proliferation, delays prehypertrophy and then prevents osteoblastic differentiation of chondrocytes (By similarity).  Also required for chondrocyte hypertrophy, both indirectly, by keeping the lineage fate of chondrocytes, and directly, by remaining present in upper hypertrophic cells (By similarity).  Low lipid levels are the main nutritional determinant for chondrogenic commitment of skeletal progenitor cells: when lipids levels are low, FOXO transcription factors promote expression of SOX9, which induces chondrogenic commitment and suppresses fatty acid oxidation (By similarity).  In addition to cartilage development, also acts as a regulator of proliferation and differentiation in epithelial stem/progenitor cells (By similarity).  In response to bone morphogenetic protein stimulus, phosphorylation is induced and then sumoylation, allowing cooperation with SNAI2 to trigger neural crest delamination (PubMed:23382206).
What are the official names of this protein?
Transcription factor SOX-9.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYDND_NOCFA
Sequence: MLRTHLAGSLRSEHAGQTVTLTGWVARRRDHGGVIFIDLRDASGVSQAVFREGEAAEQAHRLRAEYCVRVTGVVEQRPDGNENPELPTGQIEVNVRELEVLNESAPLPFQLDEQPGEEARLKHRYLDLRREGPAHAIRLRSKVNAAAREVLARHEFVEVETPTLTKSTPEGARDFLVPARLQPGNFYALPQSPQLFKQLLMVGGIERYFQIARCYRDEDFRADRQPEFTQLDIEMSFVEQADVILLAEEILVALWKLIGYEIPTPIPHMTYAEAMRRFGSDKPDLRFGVEITECTEYFKNTPFRVFQAPYVGAVVMPGGASQPRRQLDAWQEWAKQRGAKGLAYVLVNEDGSLGGPVAKNLSDAEREGLAKHVGAEPGDCVFFAAGPAKAQRALLGAARGEIARKVGLIDENAWSFVWIVDAPLFEPADDATASGDVALGHSAWTAVHHAFTSPKPESLDTFDTDPGSALAYAYDIVCNGNEIGGGSIRIHRRDVQERVFKVMGIGEQEAQEKFGFLLDAFAYGAPPHGGIAFGWDRIVALLAGLDSIREVIAFPKTGGGVDPLTDAPAPITAQQRKEAGLDAKPEQAEVKKAEQAG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKYA_BACSU
Sequence: MKDAIKRRPGIKIGAFCAMALILTGCMGQDPVDSLHHSLEKAAESEKPFQEEQNTLKELEAKENQLYDSVMKLNMDDYKKIVALSNKALENVSKREEHLKLENDSMKKSETEFEEAKTSAEHIKEKDIKEKADAAANHMEKRYTSYGTMYKEYKKALELNKKLYMQLKDKDLTRDDLDQQIDKVNASYEKILKYSGEFNEQTEKYNKAREDLYDAAGYRVKKS
What are the official names of this protein?
Uncharacterized lipoprotein YkyA.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ARO1_PARBP
Sequence: MGVPTKISILGRESIVADFGIWRNYVAKDLLSNCASSTYILISDTNLTPLYLAGFQQSFENAAAGLSPKPRLLTYEIPPGESSKSRETKAEIEDWMLTRQPPCGRDTVIIALGGGVIGDLIGFVAATYMRGVRFVQVPTTLLAMVDSSIGGKTAIDTPNGKNLIGAIWQPQRIYLDMEFLNTLPEREFINGMAEVIKTAAISSEEKFAALENDADVILAAVKSKNTPDRLRFSSIQETLKRTILSSAEFKAQVVSADEREGGLRNLLNFGHSIGHAIEAILAPQVLHGECVSIGMVKEAELARHLGILNNVSVARIAKCLASYELPTSLKDERIKRLTAGKHCSVEQIITYMGVDKKNDGPKKKVVLLSAIGRTYEPRASTVSNEDLQVVLAPSIEVYPGFPKSLNVTCTPPGSKSISNRALVLAALGSGTCRIKNLLHSDDTEVMLTALERLGAATFSWESQGEVLVVNGNGGRMVASPKELYLGNAGTASRFLTTVATLAQKGSVASSVLTGNARMKQRPIGDLVDALKSNGADIEYLENPKSLPLKITASGGFAGGEMRLDAKVSSQYVTSLLMCAPYANEPVTLRLVGGKPVSQLYVDMTTAMMRSFGIDVKKSETEEHTYHIPRGVYKNPAEYVVESDASSATYPLAIAAMTGTSCTVPNIGSKSLQGDARFAIEVLRPMGCTVNQTDFSTSVTGTAGGKLKSLPTIDMEPMTDAFLTASVLAAVARGQGSNHTTRICGIANQRVKECNRIKAMKDELAKFGVTCREHDDGLEIDGIDRSTLRHPTEGVFCYDDHRVAMSFSVLALVAPQPTLILEKECVGKTWPGWWNTLAQTFKVKLDGKEVEVEEVEVEERAKTNGVAHLDKSAASIFIIGMRGAGKTTSGVWVSKALQRPFIDLDDELEKSEGMTIPEMIKQRGWEGFRDSELALLRRVMTEKPMGYIFACGGGVVELPEARELLTQYHKTKGNVILAMRDIKEVMDFLKIDKTRPAYVEDMMSVWLRRKPWYQECSNIQYYSRITQPDGMAQVLHGFNRFLKVITGQLDSLAQMRRKENTFFVSLTFPDLTPASNILKEVTLGSDAVELRVDLLKDPQSDSEIPSVDYVAEQISVLRSRVSVPLVFTIRTKSQGGRFPDDAYDAALQLYRLAIRMGSEFVDLELSFPKQLLRTVTEMKGFSKIIASHHDPEGLLSWANGSWIQIYNKALQYGDVIKLVGVAKTLDDNASLKKFKTWAEAKHDVPLIAINMGYKGQLSRILNGFMTPVSHPSLPFKAAPGQLSAREIRKGLSLMGEIKAKKFAVIGKPVSSSRSPAMHNALFKQMGLPHTYGRIETDNVEDVKEFILSPDFGGASVTIPLKLDIMPLLDEIAPEAEMIGAVNTIVSVPAAPGDKFQSSRLIGRNTDWQGMVRCLSDAGAYSAATPTTSSAGLIIGGGGTARAAIFALNSMSYSPIYIVGRSPEKLACMASSFPADYNIRIVDDVKALESLPMVAIGTIPGDKPIELHMREVLCEILSLCEKANVEAERKTGITPKRILLEMAYKPSVTSLMKLASDAGWTVLPGLEVLVAQGVYQSEYWTDITPVYENARKAVMGVSSSDDTIS
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_STRMU
Sequence: MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIYVINQPENGRLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQATEENAHPHASATGRLVLVHNGVIENYLQIKENYLAGHNLKGETDTEIAVHLIGQFVTDGLSVLESFKKALHIIEGSYAFALIDSQNPDIIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQFMEIHDKELVVLTKDTAQVSDYDGNPVERQAYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLISTYANENGKLTVDPAIVKSVQEADRIYILAAGTSYNAGFASKSMIETLTDTPVELGIASEWGYNMPLLSKKPMFILLSQSGETADSRQVLVKANAMGVPSLTITNVPGSTLSREATYTMLLHAGPEIAVASTKAYTAQIAALAFLSKAVGEANGKKEALEFDLVHELSIVAQSIEASLSEREVIEKKVANLLATSRNAFYIGRGNDYYVAMEASLKLKEISYIQCEGFAAGELKHGTISLIEEGTPVLALISSSETVAAHTRGNIQEVAARGANVLTVVEEGLNKEEDDVVVNQVHPYLSSISMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_LEPBL
Sequence: MNMIQNILRVILGSKFERDLKKLIPIVGQINSLEKEMKETSDSLLSSQTQKFRERIARGESLDSILPEAFATVREVSLRTMGMRHFDVQMMGGIALHRGNIAEMKTGEGKTLTSTLAVYLNSLAGKGVHVVTVNDYLAKRDANWMKPIYDFLGISVGVIQHDMDHEQRKIAYSADITYGTNNEFGFDYLRDNMVSHKDHKVQRSHFFAIVDEVDSILIDEARTPLIISGSSDETTDKYVRINKIIPKLVAIEDFEVDEKARNVLLSEKGVSHVEEILGIENLYAPENVDLVHHVHQALKAHKIFQKDVDYVVQNGEVIIVDEFTGRLMAGRRYSDGLHQALEAKESVTIAKESQTLASITFQNYFRMYDKLAGMTGTADTEAEEFRKIYDLDVIVIPPNVSVRRKDSPDRVYRTEKEKFDAILAEIRELQSKKQPVLVGTISIEKSEILSKMLSSAGIQHNVLNAKFHEREAEIVANAGKPGAVTIATNMAGRGTDIVLGGAQLYKENLETWKDDDDLVRRFKESILKQELDNAELLIREMDSSVKQKRASEILESVKIWKKNHEDVLVAGGLHILGTERHEARRIDNQLRGRSGRQGDPGSSRFYLSLQDDLMRIFGSDRISGLMKWANMPEGQEIESKMVSNAIARAQKRVEGHNFDIRKHLLEYDDVMNRQRIVIYKMRNEVLENEDISSLILSFIEEAVENQIVAHCEGNNPSSWNLDSLKEWLEGLELNLEINEEDFKKTKNPQLALFEKVNAAAKQKYEDRAESIGKDIWKLLERNIFLDILDHRWKEHLYSMDHLREGIWTVGYSERNPLVEYKLQGFRMFDVAIENLKNEVVNFLFRVEVSENSKLPEERREYKKVGQEVTGGFQELSSGTPSPTVTVTTSSGGGTERKTSRRRKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: TRMB_LACH4
Sequence: MRLRNKPWAVKLVNEHPESVLQNPDPEKKIDWAARFGNDNTIEIEVGSGKGHFITTLAENNPDKNYVALELQTTAAGIILRTKLEKGLDNLQILRGDAADINCFFPENSTNVIYLNFSDPWPKTRHEKRRLTYKSFLAKYQQVLTKDGHIEFKTDNSGLFAYSVQSMNNFGMHFDFVSVDLHHEKPEIVEKNIETEYEHKFAAKGNPIYALHADFEA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: LYRA_STAAR
Sequence: MKNNKISGFQWAMTIFVFFVITMALSIMLRDFQSVIGVKHFIFEVTDLAPLIAAIICILVFKYKKIQLAGLKFSISLKVIERLLLALILPLIILIIGMYSFNTFADSFILLQSTGLSVPITHILIGHILMAFVVEFGFRSYLQNIVETKMNTFFASIVVGLMYSVFSANTTYDTEFAAYNFLYTFSFSMILGELIRATKGRTIYIATTFHASMTFGLIFLFSEEIGDLFSIKVIAISTAIVAVGYIGLSLIIRGIAYLTTRRNLEELEPNNYLDHVNDDEETNHTEAEKSSSNIKDAEKTGVATASTVGIAKNDTENTVADEPSIHEGTEKTESQHHIDNQTESNHDEDHDITSKSVESAESVKHAPQSDDLTNDSNEDETEQSLKEPATYKEDRRSSVVIDAEKHIEKTEEQSSDKNK
What are the official names of this protein?
Lysostaphin resistance protein A.
What is the protein family that this protein belongs to?
Belongs to the LyrA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPF_HALLT
Sequence: MARVKICGLTRGADLRAAIDAGADAVGVISEVPVDSPREVDPATAAELLADVPPFVTATLVTMPDSAERAVELLRTICPDAIQLHGEWTPDEIRFIRAETERKVLLAVDADDPARAEEFDRVADALVIDSTDDSGAGGTGETHDWERAGDLADRLTSPVVLAGGLTADNVAEAVRAADPFAVDVASGVELTDGRKDHNAVARFVANAGREMELA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: KDPB_AGRFC
Sequence: MSQSKQASILDSRILVPAIADAFKKLNPRTLARNPVMFVVATVSVLTTVLFIRDLITGGANLAFSFQINLWLWFTVLFANFAEAVAEGRGKAQADSLRKTRTETQAKLLNSDDRSQYKMVAGDSLKVNDVVLVEAGDIIPSDGEVIEGVASVNEAAITGESAPVIRESGGDRSAVTGGTQVLSDWIRVRITAAAGSTFLDRMISLVEGAERQKTPNEIALNILLAGMTLIFVLATATIPSFAAYAGGSIPIIVLVALFVTLIPTTIGALLSAIGIAGMDRLVRFNVLAMSGRAVEAAGDVDTLLLDKTGTITLGNRQATDLRPIPGVSEQELADAAQLASLADETPEGRSIVVLAKEKYGIRARDMQKLHATFVPFTAQTRMSGVDFEGASIRKGAVDAVLAYVDGGALQHGNAALALKTETDATRAIRAIAEDIAKAGGTPLAVVRDGKLLGVVQLKDIVKGGIRERFAELRRMGIRTVMITGDNPMTAAAIAAEAGVDDFLAQATPENKLELIREEQAKGKLVAMCGDGTNDAPALAQADVGVAMNTGTVAAREAGNMVDLDSDPTKLIEIVEIGKQLLMTRGALTTFSIANDIAKYFAIIPAMFLALYPQLGVLNVMGLSTPQSAILSAIIFNALIIIALIPLSLKGVKYRPIGAGALLSRNLVIYGLGGIIVPFIGIKLIDLAVTALGLA
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.