PharMolix/UniProtQA huggingface dataset:
Protein: RL15_ECO7I
Sequence: MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: TRMD_PSEFS
Sequence: MANLRIEVISLFPEMFSAISEYGITSRAVKQGLLQLTCWNPRDYTTDRHHTVDDRPFGGGPGMVMKIKPLEDALAQAKAAAGEKAKVIYLSPQGRQLKQAGVRELANEEALILIAGRYEGIDERFIEAHVDEEWSIGDYVLSGGELPAMVLIDAVTRLLPGALGHADSAEEDSFTDGLLDCPHYTRPEVYADQRVPDVLLSGNHAHIRRWRLQQSLGRTYERRADLLESRSLSGEEKKLLEEYILARDDS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1392_STRZP
Sequence: MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEYLAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKIVFEPVSELLK
What are the official names of this protein?
UPF0342 protein SPP_1392.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: MRAZ_RHOJR
Sequence: MFLGTYTPKLDEKGRLTLPAKFRDALAGGLMVTKGQDHSLAVYPREEFTALARKAAAASRSDPEARAFVRGLAAGTDEQHADAQGRITLSADHRRYAGLSKDCVVIGSVDFLEIWDAQAWQTYVEANEENYSQATGVALGEIV
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ENGB_CHLPD
Sequence: MKITDAAFYISAAALSGLPDLQIPEIVFAGRSNVGKSTLLNSLAGIKGLAKTSSTPGKTRLINFFLVNKAFFFVDLPGYGFAAVGHEQHEAWKKLLTTYIERRSAITLVVLLVDSRHPAMQSDREMIDYLTYLGKPYGIVLTKDDKLTQSQRIKARRVMESSALNAEFIVNYSSFSSKARLELLAHLAQYIR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: DF233_ARATH
Sequence: MGMWCTTLFMVSCVSICLILSHVQEVEAGAPPQDCWNLVTFPAKCGIHGKKKCFKEMESKYQQRFLQCTCKNLKPEPKSPKDEHDCTCQRANPYECNS
What are the official names of this protein?
Putative defensin-like protein 233, Putative S locus cysteine-rich-like protein 22, Protein SCRL22, SCR-like protein 22.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURA1_STRPQ
Sequence: MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILRNVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVLGPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMIYMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLTITGVTSLHGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFENRFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLDRGYYQFHEKLAKLGATISRSSEV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC12_CHACT
Sequence: EYCGESCYLIPCFTPGCYCVSRQCVNKN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Chassatide C12, Cyclotide chaC12.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family.
Protein: IF1_BACCN
Sequence: MAKDDVIEVEGTVLETLPNAMFKVELENGHVVLAHVSGKIRMNFIRILPGDKVTVELSPYDLNRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF_CYNDA
Sequence: MSWQAYVDDHLMCEIEGHHLTSAAIIGHDGTVWAQSAAFPAFKPEEMANIMKDFDEPGFLAPTGLFLGPTKYMVIQGEPGAVIRGKKGSGGVTVKKTGQALVIGIYDEPMTPGQCNMVIEKLGDYLIEQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin, Pollen allergen Cyn d 12.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PURA_DROWI
Sequence: MSTSSAAVNGNHYEQLHQGRTKMYKSKVDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDELLKNQAKGLSHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDFNLFSDKFKSIVATHVRLFPSINVDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNGYTCICITKLDILDTMAEIKVAVGYKRSNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVRFLESELSVPVRWVGVGKGRESIINVH
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_BURTA
Sequence: MSVADIKKSEVVAQFARGANDTGSPEVQVALLTARITELTGHFKTHAKDHHSRRGLLRMVSRRRKLLDYLKGKDADRYRALIEKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RL17_IXOSC
Sequence: MGRYSVEPDNATKSCKARGSNLRVHFKNTRETAQAIKHMALRRAQRYLKNVIAKKEIVPFRRFNGGVGRKAQAKAFGCTQGRWPKKSAEFLWQLLRNAESNADYKGLDVDRLVIDHIQVNRAPKMRRRTYRAHGRINPYMSSPCHIEVILSEKEQVVAAPSPEEDAPKKKQSKKKMARQKLMQRD
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: FUCO1_ORYSJ
Sequence: MATILLLLLGLLVGLPLLRAHGVTGSAAPTPPPLPVLPVPSYAQLQWQLSEMALFLHFGPNTFTDSEWGSVRADPAVFAPSALDAGQWARAAAAGGFGRVVLTAKHHDGFCLWPSALTNYSVAASPWKGGAGDVVGELAAAARAEGIGLGLYLSPWDRHEPVYGDTVAYNEHYLGQMTELLTRYGDVEEVWLDGAKGEGKDMDYMFDAWFALIHQLQQRVVIFSDAGPDTRWVGDEAGVAGYTCWSPFNKSTVTIGHIIPEYSRCGDPFGQDWVPAECDVSIRPGWFWHASEKPKNATTLLDIYYKSVGRNCLLILNVPPNSSGLISTEDMQVLQEFTEIRQTIFSQNFAANATVTASTVRGGLGNQQFAPSNVLQESIYSYWAPEEGQSSWEMLFDLGQSASFNVIQLQEPIQMGQRVIKFRVEILVDELWQTIVEGTTIGYKRLFQFPVVEGQFLKLSIDGARADPLISFFGVFTDSFSVTYSLENHEKPSVVNSSEVIMLRTDHSFGNKSIATM
What is the function of this protein?
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.  Active only against 2'-fucosyl-lactitol when heterologously expressed.
What are the official names of this protein?
Putative alpha-L-fucosidase 1, Alpha-L-fucoside fucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 29 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: GLD2_RAT
Sequence: MFPNSILGRPPFTPTHQQHNNFFALSPTLYSHQQLIDAQFNFQNVDLSRAVSLQPLTYGTVSPIQTSTSPLFRGRKRISDEKAFRLDGKRQRFHSPHQEPTIINQLVPLSGDRRYSMPPLFHTHYVPEIVRCVPPLREIPLLEPREITLPEAKDKLSQQILELFETCQQQASDLKKKELCRAQLQREIQLLFPQSRLFLVGSSLNGFGARSSDGDLCLVVKEEPCFFQVNQKTEARHILTLVHKHFCTRLSGYIERPQLIRAKVPIVKFRDKVSCVEFDLNVNNTVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHEINDASRGTLSSYSLVLMVLHYLQTLPEPILPSLQKIYPESFSTSVQLHLVHHAPCNVPPYLSKNESSLGDLLLGFLKYYATEFDWNTQMISVREAKAIPRPDDMEWRNKYICVEEPFDGTNTARAVHEKQKFDMIKDQFLKSWQRLKNKRDLNSVLPLRAATLKR
What is the function of this protein?
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail.  In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs.  Does not play a role in replication-dependent histone mRNA degradation.  Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs.
What are the official names of this protein?
Poly(A) RNA polymerase GLD2, PAP-associated domain-containing protein 4, Terminal nucleotidyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family. GLD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RLMKL_LEGPA
Sequence: MNYSLFISCSKGLEYLLEDELKGLGLHVTQVSPQGVYGEASLPVIYNLCLWSRLANRIQLILFSGHAAKEQAVHQLCTDFHWQTVFTHDKTIAIEFHGASEQIRNTMFGAQIVKDGIVDHFRRLNGSRPSVDKEKPQILIHAHLKNDILTVSFDLVGYSLHQRGYRKKAGKAPLKENVAAAMLLRAKWPELAAQGYGLHDPFCGSGTLVIEAAMMAAHIAPGLLRQDQSLQYWARHQSSLWEKLRTQALQQVKPLAVKLVGTDADGKIITLARSNAERAGVLPLVEFNTLPLNACRPGTKRGLVVCNPPYGERLGEVTQLVPLYQQLGTTLHTCYQGWQAAILTSSPVLAKALGLRADKQYTLYNGPLECKLYCLTLSAANKLKNTPDAPLSDNAQMLFNRLEKNRNHLQKWARKNQITCYRIYDADLPEYAYAIDIYNDYAVLQEYAPPASIPVHKAEKRSLEMLQVVPRALGIHPEKLIVKQRKQQKGSEQYQKIGKTSQRLIVTEGKAKLIVNLYDYLDTGLFLDHRLMRLKFAQLEPGTRFLNCFCYTASASVHAALAGALTTNVDLSKTYLLWAEDNFRLNDINLSKHQFLQYDCKEWMKTTRDKFDVIFLDPPSFSNSKRMSDILDIQRDHVSLINMAMRLLNPDGVLYFSTNLRQFKLEPMLKEKYAVQDITPQTIDQDFKRNSKIHHCFKIVMPHFADN
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_DESDA
Sequence: MMQSTFAIIKPDAVSRQLTGEILAAMEASGLKIVALKRLHLSKAQAAGFYAVHRERPFFDSLTDYMSSGPVVCVVLRGEDAVPRWRALMGATNPAQAEPGTLRARYGQSLEANAVHGSDAQETAAFEIGYFFNGLEISE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_XANCP
Sequence: MKALVKREASKGIWLEQVPVPTPGPNEVLIKLEKTAICGTDLHIYLWDEWSQRTITPGLTIGHEFVGRVAELGSAVTGYQVGQRVSAEGHIVCGHCRNCRGGRPHLCPNTVGIGVNVNGAFAEYMVMPASNLWPIPDQIPSELAAFFDPYGNAAHCALEFDVIGEDVLITGAGPIGIIAAGICKHIGARNVVVTDVNDFRLKLAADLGATRVVNVSKTSLKDVMADLHMEGFDVGLEMSGNPRAFNDMLDCMYHGGKIAMLGIMPRGAGCDWDKIIFKGLTVQGIYGRKMYETWYKMTQLVLSGFPLQKVLTHQLSIDEFQKGFDLMEEGKAGKVVLSWN
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_DICT6
Sequence: MGLFSFPKEEKLRKQEDFLRVLREGRPYSLSKSFIIYIRKGAEKRRIGISVNKKVGKAVVRNRIKRLIREVYRLHRPYLREDIEMLVIVKPGENIKDLDFHKVKDMLIKIWEKAGALKEQ
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PSBI_MORIN
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RECO_ECO57
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: UT107_PEA
Sequence: ATQRLPPLSTEPNR
What are the official names of this protein?
Unknown protein from spot 107 of 2D-PAGE of thylakoid.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid.
Protein: HIS1_CORJK
Sequence: MLRVAVPNKGSLSETATSILKEAGYATRGDSKSLTIADEDNGVEFYFLRPKDIAIYIASGHLDIGITGRDLAADTREEVDELLALGFGASTFRYAAPKDENWTVEQLAGKRIATSYPNLVRKDLANRGLEAQVIRLDGAVEISIRLGVADVIADVVSTGRTLRQQGLKPFGDPLCVSEAVIVGRKGAEVTAEQSVLIKRIQGILHAHNYVMLDYNVARENLDKVAAITPGLSAPTVSPLANDSWVAVRAMVPKTQANSLMDELSALGAEAILATDIRIARI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQNX_STRCO
Sequence: MRPAYDDPRTTDQPITRARPPPRAARGRRLGEEPLTEHLVDPDVPRDLHAFIAGLPKAELHVHHVGSASPRIVSELAARHADSKVPTDPEALVDYFTFTDFAHFIDVYLSVVDLIRTPEDVRLLTYEVARDMARQQVRYAELTITPFSSTRRGIDEGAFMDAIEDARKAAEAEFGTVLRWCFDIPGEAGLESAEETARLATDDRLRPEGLVSFGLGGPEIGVARPQFKPYFDRAIAAGLHSVPHAGETTGPQTVWEALIDLRAERIGHGTSSAQDPKLLAHLAERRIPLEVCPTSNIATRAVRTLDEHPIKEFVRAGVPVTINSDDPPMFGTDLNNEYAVAARLLGLDERGLADLAKNGVEASFLDAPGKARIADEIDTYTAAWLAS
What is the function of this protein?
Catalyzes the deamination of aminodeoxyfutalosine (AFL) into futalosine (FL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
What are the official names of this protein?
Aminodeoxyfutalosine deaminase, AFL deaminase, Aminofutalosine deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: MURI_ECO57
Sequence: MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLLPDLHYIYAFDNVAFPYGEKSEAFIVERVVAIVTAVQERYPLALAVVACNTASTVSLPALREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEMLGSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPEAEQLLPVLQRYGFETLEKLAVLG
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: CASP1_TOBAC
Sequence: MEKSESTKIDVVETNKERKGKAPLLGKAPVVAAAVVHAKGGGAKRGIAIFDLILRIAAFASALGAAVAMATTEETLPFFTQFFQFEASYDDLPTFTFFVVAMAIVVAYLVLSVPFSIVCIVRPHAVVPRLLLIIFDTVIIALTTGAAGSSAAIVYLAHNGNQDANWLAICQQFGDFCQRVSGAVVAAFVTVVILIFLVVLSASALRRHH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, NtCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: MATK_VITVI
Sequence: MEGVQRYFKLDRSRQDDFLYPLIFQEYIYALSYDHGLNRSILLENVGYDNKSSLLIVKRLITRMYQQNHLIFSDSNQNPFFGHNKNFYSQMISEGFGVIVEIPFSLRLVSSLEGKEIAKSHNLRSIHSIFPFLEDKFPHLKYVSDILIPHPIHLEILVQALRYWVKDASSLHLLRFFLHEYHNWNSMITPKKSISIFSKRNQRFFLFLYNFHVCEYDSIFIFIRNQSYHLRSTSYGALLGRIFFYGKIEHFVEVFANDFQTILWLFKNPFMHYVRYQGKSILASKGAPLLMNKWKYYLVNFWQCHFYVWSQPVRIHINQLSKHSLDFLGYLSSVRLNPSVVRSQMLENAFIIDNAIKKFDTIVPIIPIIGSLAKARFCNALGHPISKPSWADSSDYDIIDRFVRICRNISHYHSGSSKKKNLYRIKYILRLSCARTLARKHKSTVRAFLKRLGSEFLEEFLTEEEQALSLILPRVSSTSRSLYRGRFWYFDIICINDLANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PROFV_OLEEU
Sequence: MSWQTYVDDHLMCDIEGHEDHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HNF1B_MOUSE
Sequence: MVSKLTSLQQELLSALLSSGVTKEVLIQALEELLPSPNFGVKLETLPLSPGSGADLDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQNQGPGQSEDTCSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHNLNPLLTHGSPHHQPSSSPPNKMSGVRYNQPGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHSLLSPDSKMQITVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQGVPVINSVASSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSINTLTSMSSSKQCPLQAW
What is the function of this protein?
Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (By similarity).  Binds to the FPC element in the cAMP regulatory unit of the PLAU gene (By similarity).  Transcriptional activity is increased by coactivator PCBD1 (By similarity).
What are the official names of this protein?
Hepatocyte nuclear factor 1-beta, HNF-1-beta, HNF-1B, Homeoprotein LFB3, Transcription factor 2, TCF-2.
What is the protein family that this protein belongs to?
Belongs to the HNF1 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YS006_HUMAN
Sequence: MCEQLVCIFTYAYLKINLTKALGHHNPSYPVARAQPQTMFPSASECNAFPRVSKVPNRSGAAETALLVRVLPKPLKSQASLLSLPFIHITEQLSTHICVVLFKLFHVCLFTINNMNDCSMDAAERNAEGGLQLE
What are the official names of this protein?
Putative uncharacterized protein PP6455.
Protein: TA2R4_PAPHA
Sequence: MLWLFYSSAIIASVILDFVGIIMSLFITVVNYKTWVKSHRISSSERILFSLGITRFFMLALFLVNTIYFVSSNKERSVYLSAFFVLCFMFLDSSSLWFVTLLNSLYCVKITNFQHSVFLLLKRNISPKIPRLLPACVLISAFTTCLYITLSQASPFPELVTKRNNTSFNISEGILSLVVSFVLSSSLQFIINVTSASLLIYSLRRHIRKMQKNATGFWNPQTEAHVGAMKLMIYFLILYIPYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity).  In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 4, T2R4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
Protein: TRMA_SHIF8
Sequence: MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIALDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNITANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQFETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: RL3_PSEAB
Sequence: MTIGVVGRKCGMTRIFTEEGVSIPVTVIEVEPNRVTQFKTEETDGYRAVQVTAGERRASRVTKAQAGHFAKANVAAGRGVWEFRLGEEQYAAGDQITVDLFQAGQMVDVTGESKGKGFAGTIKRWNFRGQDNTHGNSVSHRVPGSIGQCQTPGRVFKGKKMSGHLGAERVTVQSLEIVRVDAERNLLLVKGAVPGATGGDVIVRPAAKARG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.