PharMolix/UniProtQA huggingface dataset:
Protein: YLM6_SCHPO
Sequence: MAIELGERISTSVGFLAELFLMKIPLFTVIVALLTIILGIVNIFLPIVDFFGLSWHNLINIRLHTLNTYPLVHHGVISFILGLLGIFLLMPRFERRYGTLCTIAMFFGFLEVIPAIAYLIACYVAESDDVYVGIGGWVYSLLAMYLLNLFGDLHPKLLNLPQVVRMALALVAPVLGLPLDFSITIVLHLTAVVISIIFSFAYMDFFLPRGGFLVWVETKFSKIIDAIPNYISVTEAAYYQADGAIPIQDLGSNSSGIV
What are the official names of this protein?
Uncharacterized rhomboid protein C19B12.06c.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: VL2_BPV3
Sequence: MVRAARRKRASEDDLSRGCRAGQDCPIDIKNKYEQNTLADRILKWVSSFLYFGTLGISSGKGTGGATGYTPIGGGGVRGGKGANVVRPTVLVDALGPTGVPIDPVTPDEALVPLLESSGGSTTLDVPPGGEIEVIAEVHPPPAAGDPEITIGHPEEPPILEVIPETHPTTRVRTTVSKHDNPAFTAYVASAQLPGETSASDNVFILHGFNGEYVGPAQTGEDTVFEEIELENFGVPESPPSSSTPNTSFRNILNKFQRRLYNRRLVQQVKITDRTFLTKPSKLVSWEFDNPTYTDDSLSLIFQQDVDEVSAAPMAEFQDIVTLSRPVVYEREGLVRVSRLGQRGTIRTRSGLRIGGHVHYYTDISPIRPVEDIEMRTLGEVSGDSVIMQPLAESTFVDSGDVLNEGNIEFPDSTLEDDYNEDFSRARLEITTSARSRTSIVTVQEGIPPGSVKLFINDAETIVTPHGPESNDTDRYQPFIPVTPAATPDIIITFEEGTATFFLHPSLLKRHKHKHWFF
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: TSAC_ACTP2
Sequence: MNNLENIVEQLKRNRVVAYPTEAVFGLGCNPNNESAVRALLKLKKRPEEKGLILIAPTKELLLPYIDENKLTAAHWQIFETPSERAITWVMPAKKAVPQYLTGQFDTIAVRLCCIPAVIDLCERTGFALTSTSCNLTGQEPCRTADEVKLQFGADFPVLEAETAGKTNPPEIRDIFTQHIFRQG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MK1_PALPR
Sequence: VDKPDYRPRPRPPNM
What is the function of this protein?
Antibacterial peptide active against Gram-negative bacteria.
What are the official names of this protein?
Metalnikowin-1, Metalnikowin I.
Protein: NUOI1_CERS1
Sequence: MARTSAIDYGRAAKYFLLLDFIKGFGLGMKYFFAPKHTVNYPHEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIDAEPREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETREELFYNKDRLLENGARWEAEIARNLELDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 1, NADH dehydrogenase I subunit I 1, NDH-1 subunit I 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SMR10_ARATH
Sequence: MGFSDAGIYLSDPNNLCQTELGFFHEPSLGFSDQSDPQNEFHITPPIYQELQDQDLEPKSQETNNCSRKEGATVKKEEEEEDDYCKTPTRSDQILSAMPRICPPAPRKPKRVPSRSLKVRNSYRSKRMIILNVSREIDCLFNPTSLCNKIKKARYI
What is the function of this protein?
Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle.
What are the official names of this protein?
Cyclin-dependent protein kinase inhibitor SMR10, Protein SIAMESE-RELATED 10.
Protein: FPG_RHOPA
Sequence: MPELPEVETVRRGLQPAMEGFRIDRAVAHRENLRFPLQKDFVARLTGQTVTGLGRRAKYLLADLSSGDVLLMHLGMSGSFRVVEADGETRPGEFHYPRSEDRTHDHVVFEMASGARVVFNDPRRFGFMKVFPRSEIETEPHLKGLGPEPLGNAFDASLLAKACAGKQTSLKAALLDQRVVAGLGNIYVCEALFRAHLSPKRKASTLANRKDEPTDHAVRLTEAIREVLGEAIKAGGSSLRDHRQTSGELGYFQHAFKVYDREGEPCPTCGGTVQRFVQNGRSTFWCPKCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: DRS5_AGAAN
Sequence: MAFLKKSLFLVLFLGLVSLSICEEEKRENEDEEEQEDDEQSEMKRGMWSTIRNVGKSAAKAANLPAKAALGAISEAVGEQ
What is the function of this protein?
Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria.  Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).
What are the official names of this protein?
Dermaseptin-A5, DRS-A5, Dermaseptin AA-3-6, Dermaseptin-A4, DRS-A4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LSPA_STAAR
Sequence: MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEKEVK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y692_CALBD
Sequence: MRNVYDIAYELATALKESNEFKRFKAAKEKIEKDEKLKQMISDFKKKQFELEQKRLKGEEVTSSDVYSLQQLYQIISLNPDIEEYLSAEMMLAKIIADISKIIADSIEFKDELWGFADK
What are the official names of this protein?
UPF0342 protein Athe_0692.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: SPCS1_PONAB
Sequence: MARGGDTGCTGPSETSASGAVAIAFPGLEGPPADAQYQTLALTVPKSWSPSPRSLPPALSCPPPQPAMLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYVAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQESSTDDKKPGERKIKRHAKNN
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Dispensable for SPC enzymatic activity (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 1, Microsomal signal peptidase 12 kDa subunit, SPase 12 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FENR_RICAH
Sequence: MHNTDVIIIGAGPVGLFTIFQAGMLGMKCHVIDAQETVGGQCITLYPEKPIYDIPAYPKIAAEELIKQLEFQAAPFKPVYHLNQHATDLNKQGDFFEIRTSKNTIIKSKAIIIAAGAGSFGPNKPPLANIEDFEGKSVFYFINNKSKFAGKNIVIAGGGDSAVDWAISLSEIANKIYLVHRRDKFTAAPESVRQLRDIAETGKIELVTGYQLNALDGNNGTLQTVIVKDLQNNIRKLDANVLLPFFGLKQDLGSLANWGLDVKLHHIEVDNSYYQTNIEGIYAIGDIAHYAGKLKLILTGFAEAASSIHHAYIRVFNGQALHFEYSTTKYGERK
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: KC1G3_HUMAN
Sequence: MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETKCCCFFKRRKRKTIQRHK
What is the function of this protein?
Serine/threonine-protein kinase.  Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  It can phosphorylate a large number of proteins.  Participates in Wnt signaling.  Regulates fast synaptic transmission mediated by glutamate (By similarity).
What are the official names of this protein?
Casein kinase I isoform gamma-3, CKI-gamma 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Protein: GPA1_SCHPO
Sequence: MGCMSSKYADTSGGEVIQKKLSDTQTSNSSTTGSQNARVPVLENWLNIVLRGKPQNVESSGVRVKGNSTSGGNDIKVLLLGAGDSGKTTIMKQMRLLYSPGFSQVVRKQYRVMIFENIISSLCLLLEAMDNSNVSLLPENEKYRAVILRKHTSQPNEPFSPEIYEAVHALTLDTKLRTVQSCGTNLSLLDNFYYYQDHIDRIFDPQYIPSDQDILHCRIKTTGISEETFLLNRHHYRFFDVGGQRSERRKWIHCFENVTALLFLVSLAGYDQCLVEDNSGNQMQEALLLWDSICNSSWFSESAMILFLNKLDLFKRKVHISPIQKHFPDYQEVGSTPTFVQTQCPLADNAVRSGMYYFYLKFESLNRIASRSCYCHFTTATDTSLLQRVMVSVQDTIMSNNLQSLMF
What is the function of this protein?
Implicated in the mating and sporulation pathway.  Probably coupled to mating-factor receptors.  May act in concert with Ras1.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-1 subunit, GP1-alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
Protein: TOLB_PSEPU
Sequence: MIKRLRGLLVMLCCVAGMAVAEEKNILVTSGSDRATPIAVVPFGLQGGSVLPEDIADIIGNDLRNSGYYSPIPRQNMISQPSQASEVIFRDWKALGAQYVMVGSIVPSGGRLQVQYALFNVATEQQVLTGSVAGSTDQLRDMAHYIADQSFEKLTGIKGAFSTRMLYVTAERFSTNNTRYTLQRSDYDGARAVTLLQSREPILSPRFAPDGKRIAYVSFEQKRPRIFVQNIDTGRREQVTNFEGLNGAPAWSPDGSRLAFVLSKDGNPDIYVMNVASRQISRVTAGPGINTEPFWGKDGNTLYFTSDRGGKPQIYKQSVSGGGAERVTFVGNYNANPKLSADEKTLVMIHRQQGFTNFKVAAQDLQRGSVKILSETSLDESPTVAPNGTMLIYATRQQGRGVLMLVSLNGRVRLPLPTAQGEVREPSWSPYLN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL21_PSEA7
Sequence: MYAVIVTGGKQHKVTEGEFLKVEKLDIATGEAIDFDRVLLVANGDDVKIGLPVVEGAKVTAEVVSHGRHDKVRIIKFRRRKHHMKRQGHRQWFTEIKITGIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RK14_DAUCA
Sequence: MIQPQTLLNVADNSGARELMCIRIIGASNRRYAHIGDVIVAVIKEAVPNMPLARSEVVRAVIVRTCKELKRDNGMIIRYDDNAAVVIDQEGNPKGTRIFGAIARELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPBA_BPT4
Sequence: MTKITVNYTVDVKDIQPKHVRSESNPQNQNKIRRAWVLSLSDNAMEVIQNKIKSAPARHAYYEAIDREVSNKWIELMRKHTTESLNAGAKFIMTSCGERLEDDYCGNADERLIVAAQIVAETIAADFNR
What is the function of this protein?
Binds to host RNA polymerase core.
What are the official names of this protein?
15 kDa RNA polymerase-binding protein, P15k.
Protein: RUVA_WOLPP
Sequence: MIGNLRGIVDEVCSDHIILNVNDVGYIVYLSAKTLSACSIGSRVKLLIDTYANSRENVTQLYGFISKEEQQCLRLLVKVSGVSYKTAMSILSKLTPEQLFLAIINEDKLALKVSGLGLKLINRIITELNGKVSKLEINNNHFHSISEDALSALINLGYERTKAYDTIKKIEDESPNLDTKDIIRMALKTI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: F16A2_BRASB
Sequence: MAREWPMEQSPTLQAHLALQNADADCAAVIEALADAARELARQIAIAPLAGFDEGAATVNADGDVQKALDIVADNLMRDALRKAPVAGILSEEVDRPETVNAAAPLCVAIDPLDGSSNLQNNISVGTIFSIRPRGRDVLSSFFEPGTAQRAAGFFVYGPQTCLVLAIDHRVDLYVLHPTLREFVLARSGLRIPQDTPEFAINASNRRHWSGTVRNYVDECLAGAAGPRGRDFNMRWIASLVAEAYRILMRGGVFLYPADSRPGYREGRLRLVYEAHPMALIMEWAGGSASSGRSRILELSARSPHQRAPLIMGDVRLVRDVDQLHEGVEPLFETSDAPLFARRGLFR
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 2, FBPase class 1 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2FA_RAT
Sequence: MAALGSSSQNVTEYVVRVPKNTAKRYNIMAFNAADKVNFATWNQARLERDLSNKKIYQEEEMPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKGIKKGGVTENTAYYIFTQCADGAFEAFPVQNWYNFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRSRKKPSELRIHDLEDDLEMSSDASDASGEEGSRASKAKKKAPVTKAGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSPDEAEGKPKVPQQEDGPKGVDEQSESSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSDDSDSSEESDIDSETSSALFMAKKKTPPKRERKPSGGSSKGTSRPGTPSAEAASTSSTLRAAASKLEQGKRTSETPAAKRLRMDTGPQSLSGKSTPSSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMIGDKMHFSLKE
What is the function of this protein?
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.  It promotes transcription elongation (By similarity).
What are the official names of this protein?
General transcription factor IIF subunit 1, Transcription initiation factor IIF subunit alpha, TFIIF-alpha.
What is the protein family that this protein belongs to?
Belongs to the TFIIF alpha subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VPC40_MYCTO
Sequence: MIAPDTSVLVAGFATWHEGHEAAVRALNRGVHLIAHAAVETYSVLTRLPPPHRIAPVAVHAYLADITSSNYLALDACSYRGLTDHLAEHDVTGGATYDALVGFTAKAAGAKLLTRDLRAVETYERLRVEVELVT
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its cognate antitoxin is VapB40 (By similarity).
What are the official names of this protein?
Ribonuclease VapC40, RNase VapC40, Toxin VapC40.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: KN14P_ARATH
Sequence: MNPMRDQPGSPYGDSTPRSPFSPFSPLSVDDRHRNHADTKTPRSPFSPFSPLSGDERHKSLAESKFQQALASSGQLDPLSPGSMHHGGHKFHEVFQMKQGRYDLQASKISEMMKSSSLDNAPTQSLLSVLNGILDESIERKNGEIPQRVACLLRKVVQEIERRISTQAEHLRTQNNIFKTREEKYQSRINVLEALASGTGVEHEIATQQLRQIETEKSMWEEKKKHEEEDMVKLMKQNDQHNLEISALKQELETTKRKYEQQYSQIESQTKTEKSKWEEQKKNEEEDMDKLLKENDQFNLQISALRQELETTRKAYEQQCSQMESQTMVATTGLESRLKELEQEGKVVNTAKNALEERVKELEQMGKEAHSAKNALEEKIKQLQQMEKETKTANTSLEGKIQELEQNLVMWKTKVREMEKKSESNHQRWSQKELSYKSFIDNQSQALLELRSYSRSIKQEILKVQENYTDQFSQLGKKLIELSNAAENYHAVLTENRKLFNELQELKGNIRVFCRVRPFLPAQGAANTVVEYVGEDGELVVTNPTRPGKDGLRQFKFNKVYSPTASQADVFSDIRPLVRSVLDGYNVCIFAYGQTGSGKTYTMTGPDGSSEEDWGVNYRALNDLFKISQSRKGNISYEVGVQMVEIYNEQVLDLLSDDNSQKKTLGILSTTQQNGLAVPDASMYPVTSTSDVITLMDIGLQNRAVGSTALNERSSRSHSIVTVHVRGKDLKTGSVLYGNLHLVDLAGSERVDRSEVTGDRLREAQHINKSLSSLGDVIFSLASKSSHVPYRNSKLTQLLQTSLGGRAKTLMFVQLNPDATSYSESMSTLKFAERVSGVELGAAKTSKEGKDVRDLMEQLASLKDTIARKDEEIERLQHQPQRLQKSMMRRKSIGHTDDINSDTGEYSSQSRYSVTDGESLASSAEAEYDERLSEITSDAASMGTQGSIDVTKRPPRISDRAKSVTAKSSTSVTRPLDKLRKVATRTTSTVAKVTGLTSSSKGLASSSIKKTGSTSSLAKSSKRWA
What are the official names of this protein?
Kinesin-like protein KIN-14P.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.
Protein: FK109_ARATH
Sequence: MFCSCLEIVFFLAGRHHSQFPSLPDENETNKSSDSPPTVFSSLPDELILNCLARVSRFYRPSLSLVNKEFQSLIASPDLEATRSRIGVTENHLYVCLESNKNNPNPRWFTLAPIPKEQKVKPIIPSFPYQHPTSSTFVSIGSEIYIIGGFVKRKRSRRVLVLDCRSHQCRRLPNMALPRVSAAADVIDGKIYVVGGSKSKNIDNWGEVFDPETQTWEPIFPTTVDLTTQKSVFPGKLVMGGKVYDMDGLKVNLNLNSCVVEIDNMMCQISVCKGILVWYDSEEDLVWNKSMVFDRLGLDWTKEGKTEIWCAEISLERRGFGELWGFVEWSKKVFTYDGCDSPSDFFLHSAIVTY
What are the official names of this protein?
Putative F-box/kelch-repeat protein At5g03000.
Protein: TEX38_MOUSE
Sequence: MWISLCIGFLGLCSVLIGSCILFLHWKKNLQREERAQQWVEVMRAATFTYSPLLYWINKRRYHGMNVAINTGPPPAVTKTEPEDQNSDSLWELDLSEGRNFVVQDSSPRGEASDLLQHVLGIPKQPQSSKMSQPRTDSPFPLPIFQEVPFALSLCHLPPMLNHSVSYPLANRPERNVPFCSLPTLAHGTNCFNAKPFALEL
What are the official names of this protein?
Testis-expressed protein 38, ATPAF1 antisense RNA 1, ATPAF1 antisense gene protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LOLB_NITOC
Sequence: MKWCRLSIILMSLILLAGCMPLRQPSPSADPQQTWQERQFALQEIEDWNLSGRLAINAIKEAWTGTLRWTQRGDEFKILWLFPLGQGSVELYGNPDRVTLRAPKEEPMIATSAEELLGTRLGWSLPVSGLRYWLLGLPAPGLPVVKSSLDSFGRLLRLSQGGWQIRYLDYKWIENFALPGKIFLEHPKLRLRLVIDHWQLG
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: MGRN1_RAT
Sequence: MGSILSRRIAGVEDIDIQANSAYRYPPKSAGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDTDSPTEDGEKPRVLYSLEFTFDADARVAITIYCQAVEEFVNGMTVYSCKNPSLQSETVHYKRGVSQQFSLPSFKIDFSEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHVDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSSECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPISFSPVLAQSVDHDEHSNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGISDGLSQASCPLAGLDRIIENGIQKGKTQSKSPDSTLRSPSSPIHEEDEEKLSEDPEAPLPPSGVELVLQESSSPESFGTEEVGEPSLKQGSRVPSIDDVLQDGSPQHHGCSQPVPPADIYLPALGPESCSVGIEE
What is the function of this protein?
E3 ubiquitin-protein ligase.  Mediates TSG101 monoubiquitination at multiple sites.  Plays a role in the regulation of endosome-to-lysosome trafficking.  Impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production.  Does not inhibit ADRB2-signaling.  Does not promote MC1R ubiquitination.  Acts also as a negative regulator of hedgehog signaling (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase MGRN1, Mahogunin RING finger protein 1, RING-type E3 ubiquitin transferase MGRN1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Early endosome. Note=The endosomal localization is dependent on the interaction with TSG101.
Protein: EX7L_HELPY
Sequence: MDVLSVSEINAQIKALLEATFLQVRVQGEVSNLTIHKVSGHAYFSLKDSQSVIKCVLFKGNANRLKFALKEGQEVVVFGGISVYVPRGDYQINCFEIEPKDIGSLTLALEQLKEKLRLKGYFDEENKLPKPHFPKRVAVITSQNSAAWADMKKIASKRWPMCELVCINTLMQGEGCVQSVVESIVYADSFHDTKNAFDAIVVARGGGSMEDLYSFNDEKIADALYLAKTFSMSAIGHESDFLLSDLVADLRASTPSNAMEILLPSSDEWLQRLDGFNVKLHRSFKTLLHQKKAHLEHLVASLKRLSFENKHHLNALKLEKLKIALENKTLEFLRFKKTLLEKISTQTLTSPFLQTKTERLNRLENALKLAHANLKLPQFGALVSKNNQAIELEALKRGDKIELSNEKTRASAEILSVDRV
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKBP2_CANGA
Sequence: MLSQIWILFTFMVCVIASKSKSDGLKFEITKKIPISKCKLKALPGDMVSVHYTGSLAENGKVFDSSLRRNEPIQFKLGAGQVIAGWEQGITGMCLGEKRTLHIPPELAYGSRGAGGVIPPNAVLDFDVELVDIARN
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 2, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: ABRX1_DANRE
Sequence: MEEFNTTVRISGFVLSSLMFHHLNSDADVEGLILGESVGEENCRITDSQIDHIQFEHTLNIQKHIPCHKLHSFYSNVGDVSEQKIRQILSDYKEENVIGWYRQRRNTRQQMTFMEQVIHRNMRKILSNQELVFMLLTPSQGTASGSTHRLEFSAFIWHSSQYINIPISVSNLGNLEQQDYWRVSSTCPSLGQSQAVNQHRAKFFCSGDDLREVRNVSDMNDALLAEMQKVCVEVEKSERTVEKLQEDIAQLKEAIGKQKTHPEEHETPISACPEEPKENTLLCSALRTLFPSVPSLRTQTLTVHGFPVLQLCCNTDHNIDISTKLPQILENQHSRRKVTAPRLRKKCLVASFPQRLKRKRKTREVSESASESGSDTEIEMNGQSGSNSPVF
What is the function of this protein?
Involved in DNA damage response and double-strand break (DSB) repair.  Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of brca1.  The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at DSBs.  This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX (By similarity).
What are the official names of this protein?
BRCA1-A complex subunit Abraxas 1, Coiled-coil domain-containing protein 98, Protein FAM175A.
What is the protein family that this protein belongs to?
Belongs to the FAM175 family. Abraxas subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).