PharMolix/UniProtQA huggingface dataset:
Protein: RF1_MYXXD
Sequence: MIDKLEDVERRFERLTADLSNPDVLADSARLQKVSKERAGLEKLVEAFRTYRKVLADLSEVEAWLGSSDADEKAFARESLPGLKEQRDELEASLKILLLPKDPNDEKNVILEIRAGAGGDEAALFAEEVMQMYLRYADRRGWKADILDMSPGNAGGVKDATVTLSGDAVFSSMKYESGVHRVQRVPATETQGRIHTSTITVSVMPEAEDVDVQVNPADIEMQVMRSTGSGGQSVNTTDSAVRLIHHPTGIVVKCQQEKSQLKNRTMAMRMLRAKLYDIEQERIRNERDSARRAQVGTGDRSEKIRTYNFPQDRLTDHRIGLTVHNLPGVMAGDVEDVITACRTFYQAEALKAQTAGGPKPSA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPL2_YEAST
Sequence: MGTYTPLIYNIYNVHIWVFTESQGQIGQMSPRGKMETAVSQGQHKQLKDGHQHKGRKLSEEIASLLRLKECRRLNPASYYTPRRTSQSQSLSGSTFKEYNEYINEKDSSRAQRQNAAAVLSKLAHDFWENDCVIDEDIFEDSSDEEQS
What is the function of this protein?
Putative cyclin-dependent kinase (CDK) inhibitor necessary and sufficient for PHO pathway-dependent down-regulation of low-affinity phosphate transport.
What are the official names of this protein?
Putative cyclin-dependent kinase inhibitor SPL2, Suppressor of PLC1 deletion protein 2.
What are the subcellular locations of this protein?
Cytoplasmic granule. Cytoplasm.
Protein: HIS6_VIBC1
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAQRYAEEGADELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIKSAEDAARILEFGADKVSINSPALANPQLITDLADKFGVQCIVVGIDSYYDKETGKYQVYQFTGDEERTKATQWETRDWVQEVQKRGAGEIVLNMMNQDGVRNGYDIKQLNMVREVCNVPLIASGGAGAMEHFAEAYQKANVDGALAASVFHKQVINIGELKQYLKQQGIEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_PSEAB
Sequence: MTAQLIDGKAIAANLRQQIAQRVTERRQQGLRVPGLAVILVGTDPASQVYVAHKRKDCEEVGFLSQAYDLPAETSQDDLLALIDRLNDDPAIDGILVQLPLPAHLDASLLLERIHPDKDVDGFHPYNIGRLAQRMPLLRPCTPKGIMTLLASTGADLYGMDAVVVGASNIVGRPMALELLLGGCTVTVTHRFTRDLADHVSRADLVVVAAGKPGLVKGEWIKEGAIVIDVGINRQADGRLVGDVEYEVAAQRASWITPVPGGVGPMTRACLLENTLHAAEHLHD
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: BIMB_EMENI
Sequence: MAVTSFPADSLASMESVKQTVRSTSTCSAATVLSLQTLFRSAGEMETTLRRTARGTKATATNATASSRAKTTRTKSTSTSTTRTKTPAQDVSTFTSTSASLADTRLSNQEKLVLATEVFNSTLKTLSDAVKTVMSISKEKKDASPTKRGTTTKGRVKTSQPDLTDNENGVSAVAECARLSLSCLRMLRTDAMVDGGLPNLQLEQGACVLAGRLLALGLNDAAYKELRGLKRRIQSYLEELPSGRKRTGRKDAEDGEETAKERMSDLLSFSDIANARSIHGLLVSFQSNALRLIAAEKRPATVQKLVPSLQLTDESSPANVIMASIDSGALTKDKAAVQLQLLSSTVLSLSASGASTGKERLRPSIVLSLQLLALEIRCMSWKLSGHACEDNKEMWDPLARYIGAFAQATKSIEKAEFAVIYKNIVRLQSAFSKTQNCATRSTDNLSVARIATILGQLAQDAGCFDEALQLFTESLNPLSSSQCLGMATVRCKIAALHFQAFKSSVKLPGDVSDAVSQATAALSISLKGSSHDLDELLVQAAKLKKLAMGWFGDLISKGQGSQCENVVFPRICEFLSSFVRFLRRYIGRRPENDELNDREIFQKRIDAAQNIVLAAVDSTIAIGKLSVMSQRPAWEETVSTLLDCQRLLATIEPFDEVDVATADSIDQALVKLSNLFWSRYLKEKEAGKNARELLPLLKQSAYLLSGCSPSQRATGFAPLKYERLAHTYIEGNMVSEAEVAFRQSITDHIAAGALDKIASSTDGCFPHQMNQDPKRSGFTLGRVLSAYLKVKLRNKRSAVNEIFDDETLPSVQRGHVLEWQLGILTEIHGTSNNDNVFRSVFAEVATRLFKVYPAEQHPVRRLRVLLSGLRFALEQPGFLDSSLLQRFADEGRKGLDDDDYQDDDDIKSLAVYLKNSVRLTLGLQQGSLGPEELELIVSTWTSILRFCHDLKSLVACVGNVEYFLLQMKAVVDYTEIHGLWKFQLSTLELVLRVTELHGAGTFSEAIIVLSRLVLQYCRMGFCIKAHSLLSRADGYIANHEVSCLARLSYELARVGFLLETGDNQKAATVLSTARMIYEKHQATEDLDACSVLTKISWERLVADAAFMSSRLSFAQGSIKDALYFAKLSVRLNCRIWAKVEKLAQKKQEKAVVGDSSELEIVVEGMAKLEVSQTSSTYSQGAPFWPHIGSHHSSLLHLANLSAHHGLFQDAIYYGEQALKINKSLNANVRLIASQAHLGSHWILGGHISEGQQLLASAKALSDKLGSSIELVSLRLSLAALHRVEGDYRNEYRTLREAEKLLGGLFESQADSADIPDLEEKMDKLRVRPKSRSTRQPATTATRRTRSATTSARSTPKPPQSVEATNASNTLLQMKSEILLQQAASLRAQREFEAASTLLSDARKFAVTRNSRISVHLGESEHLLADAIRNFANHAVYCVLPESTISLPSLEPKAASESSSKSATRKTRAPTRGTRTKAQAATEDFSVMLSKAGDCLNGIFDTATQLGSTLDSHSASRLMSRISMLSHVTASPNHILWPHSPANMNEVGRIGAFARERAAIRIDKRLADYCDPLLWPRSELESEGVSPDFTKEYVDILPDNWNVLSLSLSADRAEFVVSRLHRGCSPFLLRLPLRRGNSEDEEEQFTFEDGRDEMKELIRLANESAHAAKLQVDRQMKKEWWKNREALDRRMENLLQNIENVWFGGFRGIFSPIPLCEKSLARFASAFENILENHLPSRRKGSRAQGPKLTLHPNVLELFVGVKGLDDQEDPEDTLMDLLYFVVDILQFQGERNAYDEVDFDMMVVETLDAVRAYHEAAKDQATQRPNNTVLVLDKSLHLFPWESLPCLQGLPVCRVPSLECLRDRVLHLRSGKQSALSIDRRNGTYILNPTGDLKTTQETFEKDLSSLKGWTGMVNRQPTEDEFKDSLQSKSLFLYFGHGSGAQYIRGRTVKRLDRCAVAFLMGCSSGTLTEAGEYEPYGTPMNYLQAGSPALVATLWDVTDKDIDRFAKATFEHWGLIGNGHRGNEGIGEAGVALDAAVSQSRGACVLKYLNGAAPVVYGVPGVFLH
What is the function of this protein?
Required for nuclear division.  Could function in the mitotic spindle.
What are the official names of this protein?
Separin, Cell division-associated protein bimB, Separase.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL35_LEPIN
Sequence: MPKLKTNRAAAKRFKFTKNNKIKRKSMNTRHILTKKGPKRRRRLRGLTLVHNSDWKSIVRLMPYGVR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: HYPA_AERS4
Sequence: MHEMSLAVAAIDLAAEQATQRGFNKVTALWLEVGSFSCVDPDTIAFCFEAAAKGTVVEGAQLHFQHQAAEAWCYDCDKTVTLTERGQACPECGGYKLRVAQGDSLRITDIEVS
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: BIOF_ARATH
Sequence: MADHSWDKTVEEAVNVLESRQILRSLRPICMSRQNEEEIVKSRANGGDGYEVFDGLCQWDRTSVEVSVSIPTFQKWLHDEPSNGEEIFSGDALAECRKGRFKKLLLFSGNDYLGLSSHPTISNAAANAVKEYGMGPKGSALICGYTTYHRLLESSLAQLKKKEDCLVCPTGFAANMAAMVAIGSVASLLAASGKPLKNEKVAIFSDALNHASIIDGVRLAERQGNVEVFVYRHCDMYHLNSLLSNCKMKRKVVVTDSLFSMDGDFAPMEELSQLRKKYGFLLVIDDAHGTFVCGENGGGVAEEFNCEADVDLCVGTLSKAAGCHGGFIACSKKWKQLIQSRGRSFIFSTAIPVPMAAAAYAAVVVARKEIWRRKAIWERVKEFKELSGVDISSPIISLVVGNQEKALKASRYLLKSGFHVMAIRPPTVPPNSCRLRVTLSAAHTTEDVKKLITALSSCLDFDNTATHIPSFLFPKL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide (PubMed:16299174, PubMed:21730067).  Required for the biosynthesis of D-biotin that prevents light-mediated cell death and modulates defense gene expression, probably by avoiding hydrogen peroxide H(2)O(2) accumulation (PubMed:22126457).
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Biotin synthase 4, Biotin synthase F, AtbioF.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Peroxisome. Note=The cytosolic localization observed in PubMed:16299174 is probably due to the lack of PTS1 domain at the C-terminus of the reporter gene construct.
Protein: ACKA_ACTP2
Sequence: MSKNLILILNCGSSSLKFAVLDPKTGDEKLSGLAEAFNLEDARIKWKLHGEKGNADLGAGAAHSEALTFIANELLSEELRSSIGAIGHRIVHGGEQFTSSVVINDDVVKGIEHAIQFAPLHNPAHLIGIKEAFRIFPELKEKNVAVFDTAFHQTMPEEAFLYALPYKLYKEHGIRRYGAHGTSHLFITSQVAELAGKPVDQTNAIICHLGNGGSVSVVRNGKCIDTSMGLTPLEGLVMGTRSGDIDPAIVFYLYKNLGMSMEQIEDTLVKKSGLLGLTEVTSDCRYAEDNYEDASKPEAKRALDVYSYRLAKYIGAYMAILGDDHLDAIAFTGGIGENSGHVRELALNHLKLFGVKLDVERNLAARFGKSGVITADDSTFKAVVIPTNEELVIAQDTAKLAL
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFFE_SCHPO
Sequence: MSVSTKRLEMDEEAEEAFDLFDVTHKGYIDFEDLRRSCAQLGENLTKEQLQLMLDLAGTNGKVSREEFAELWIHIS
What are the official names of this protein?
Uncharacterized calcium-binding protein C1687.14c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SUHB_BUCAP
Sequence: MHPMLNIAIRAIRKGGNIIVQNYDTQKFIKEDLDKKKIFIKNIMYKTYRIISEVIYKSYPNHIILNKNTDLIKNEKNTLWIINELDGKNNFIKNFPHFCISIAVIMKNNTEISVIYDPIRNDLFTAVKGQGSQLNGYRIRCNNINSLNYSTIAINLPLKHYAKSLFYLKIYKKLILSGISLRCTGSTLLDLAYVASGRIDCLFDFNPQSINLIAGKLQAREAGCLTSKFTENSEKKSEKGNFCTSNLTSSSKFMRLITEKISQCYSFNN
What is the function of this protein?
Part of the processive rRNA transcription and antitermination complex (rrnTAC).  The complex forms an RNA-chaperone ring around the RNA exit tunnel of RNA polymerase (RNAP).  It supports rapid transcription and antitermination of rRNA operons, cotranscriptional rRNA folding, and annealing of distal rRNA regions to allow correct ribosome biogenesis.  This subunit may play a central role in organizing the structure.
What are the official names of this protein?
Nus factor SuhB, Inositol-1-monophosphatase, I-1-Pase, IMPase, Inositol-1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_LISW6
Sequence: MHYPEPITKLMDSFMKLPGIGPKSAARLAFYVLDMKEDDVLDFAKALVDAKRNLSFCSVCGHITDKDPCYICSDTSRDRSVICVVQESKDVIAMEKMRDFHGLYHVLHGTISPMDGIGPEDINIPDLLKRLQDDTIEEVILATNPNVEGEATAMYISRLLRPSGIKVTRIAHGLPVGGDLEYADEVTLSKAMEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: YNFB_ESCF3
Sequence: MNILSGKLPFLLGAVFAGSVVLATSVQAETSKLIIESGDSAQSRQHASMEKEQWNDTRMLRQKVNKRTEKEWDKADAAFDNRDKCEQSSNINAYWEPNTLRCLDRRTGRVITP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: BZZ1_YEAST
Sequence: MSADLSIGNEIKDSFKETHKWVQNNLKWLKDIEQFYRERAKLEKDYSERLSRLSAEYFNKKSSTSVPISVGDTPTTTPGSIEAAGVVAWNEILSQTDMISKDHDQLSTDFENHVANQLSGLFTKLDMTLSKINGFNNDMVNKKDNIYHELEKAKKDYDEACSTMEMARNRYTKASNDRNKKKLDEKEMEMNKCKNEYLIKINQANRTKDKYYFQDVPEVLDLLQDVNEAKTLFLNDLWLKAASVENDLGANVSKRLQAANSVVKQNKPSLNTAIFIKHNLKNWKEPQDFVYKPSPVWHDDEKFAVPSSLEVEDLRIKLAKAENDYNSLQDKTQNELSKLSTLNKIKHEMKTNEDNINATKFYDTLKEYLNVVSPFTSHETLKLQAEVQIESIQNNVPEEYDLSTDNIDLSKTKKKSGIFSKFKHNILNVDSKPSSGGSTGNGNGGPLHITSLFNTSRRTRLGSAPNNAGEDSDNNSIRTTSTNNTKKTTQNSSDDGKNKVLYAYVQKDDDEITITPGDKISLVARDTGSGWTKINNDTTGETGLVPTTYIRISSAATVKANDRGPAPEVPPPRRSTLPVRTMEAIYAYEAQGDDEISIDPGDIITVIRGDDGSGWTYGECDGLKGLFPTSYCK
What is the function of this protein?
Plays a role in endocytosis and trafficking to the vacuole.  Functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress.
What are the official names of this protein?
Protein BZZ1, LAS17-binding protein 7.
What is the protein family that this protein belongs to?
Belongs to the BZZ1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=localizes in cortical actin patches in a LAS17-dependent manner.
Protein: RL34_GEOSE
Sequence: MKRTYQPNRRKRSKVHGFRARMSTKNGRKVLARRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: HMR2A_PANGI
Sequence: MDVRRRPVKSLSSAKTATAGEPPKSQQQHPKASDALPLPLYLTNGLFFTMFFSVMYFLLHRWREKIRNSTPLHVVTLSELAALVLLMASVIYLLGFFGIGFVRSVIRPSPDAWDILEDDNAINEEDSRREPCAEAIDCSLPPKPKIVHMVPQKALNPKSAFADMMVEQPALAIAPLTEEDEEIVKSVVTGKIPSYSLESKLGDCKKAASIRREALQRITGKSLAGLPLDGFDYKSILGQCCEMPVGYVQIPVGIAGPLLLNETEYSVPMATTEGCLVASTNRGCKAIYASGGATSVLLRDGMTRAPVVRFSTVKRAAELKFFLEEPLNYDTPAHVFNKSSRFGRLQGIKCAVAGKNLYIRFTCSTGDAMGMNMVSKGVQNVLDFLQSDFPDMDVMGISGNYCSDKKPAAVNWIEGCGKSVVCEAIIKEEVVKKVLKTNVAALVELNMLKNLAGSAVAGALGGFNAHASNIVSAVYISTGQDPAQNVESSHCITMMEAVNNGKDLHISVTMPSIEVGTVGGGTQLASQSACLNLLGVKGASKESPGSNSRLLASIVAGSVLAGELSLMSALAAGQLVKSHMKYNRSSKDITKLSS
What is the function of this protein?
Catalyzes the synthesis of mevalonate, the specific precursor of all isoprenoid compounds present in plants (By similarity).  Component of the triterpene saponins (e. g.  ginsenosides or panaxosides) and phytosterols biosynthetic pathways (PubMed:24569845, PubMed:29378087).
What are the official names of this protein?
3-hydroxy-3-methylglutaryl coenzyme A reductase 2-A, HMG-CoA reductase 2, Hydroxymethylglutaryl-CoA reductase, PgHMGR2.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Plastid, chloroplast membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein. Note=Localized in intracellular vesicles.
Protein: PLSX_STAAT
Sequence: MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYNLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNHDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: PUR5_BURM9
Sequence: MNPPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKKYREPVLVSGTDGVGTKLKLAFHLNKHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVETAATVVKGIATGCELAGCALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSKIIDGSTIAEGDVVLGLASSGIHSNGFSLVRKIIERANPDLSADFHGRSLADALMAPTRIYVKPLLALMEKIAVKGMAHITGGGLVENIPRVLRDGLTAELDQHAWPLPPLFQWLQQHGGVADAEMHRVFNCGIGMAVIVSAADADDALRQLADAGEQVWKIGTVRASREGEAQTVVV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALB32_ARATH
Sequence: MAVWRSCLRASSSRHRLSSLFFSHHLKPSSFISHSPPLFSPSPSPSPTCFSPLHRLLSSGPEFPIGSQEIIPTDDSSLPVLAVVDFLEGFHEFTGLPWWMIIASSTVAVRLALLPLLILQLKKLKTISELLPKLPMPIPETPTLKGSIDQFSHFLKESRAIGCPSFLWFFPYLSVQLPCFFLLMASIRKMSLDGHPGFDSGGVLWFQNLSDLPGGSFGPVFPILIATFHYINIQISFDTSTIRQTTGLTGLLMRYYKLYLEILSVPLFFVGYAIPQGSLVYWVTNSSVNIFQQLSLKHPTVGAKLGLLSQGATPGMGHSMEISESVIKYVDSDSKEQTLSLQTLTPEELLSLSVQVLSKGDKETSIQLLRLALEKDPGYVRGLVLMGQALLQKTQLSEATEYLELAISKLLDEDPSDAEDVELLMLASQWAGAAYVQQGKLKSGIIHLERVAKLREPGDPKSKEHYFEALLLLSSALYKEGQSDEAAKILRVVVDHNPAYKPLLEQCEDENELVSDLVSRRKDHF
What is the function of this protein?
Probably required for the insertion of integral membrane proteins into the chloroplast thylakoid membranes.
What are the official names of this protein?
ALBINO3-like protein 2, chloroplastic, Ath5.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC (TC 2.A.9.2) family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: P1L12_HUMAN
Sequence: MGAAAPAESADLGNFWKAGEPLLQGPDALAAPMSRSPSTPQTTPSPQGRQSPWPLRSLTQSHIQYFQWGRPVPSTHLIEVRPTQDPAKPQRVVSEGWRRPALPGETALGRDLSCAWEGCMKGGLCRAWNPGRTWSPVTIGIAPPERQESPWRSPGQRARPAGRPAAQELLDPCTRETLLGALSQCPKGSARFDGPLWFEVSDSKGGRRNLQPRPSAFKPLSKNGAVASFVPRPGPLKPSLGPWSLSFCDDAWPSVLVQPAPSAIWDFWEATTPSCGSCSRVSFALEVTQSAGPFGS
What are the official names of this protein?
POM121-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the POM121 family.
Protein: PAF1_DANRE
Sequence: MAPTIQTQAQREDGHRSSAHRTVPERSGVVCRVKYGNSLPDIPFDPKFITYPFDQHRFVQYKATSLEKQHKHELLTEPDLGVTIDLINPDTYRIDPNILLDPADEKLLEEEIQAPSSSKRSQQHAKVVPWMRKTEYISTEFNRYGVSNEKVEVKIGVSVKQQFTEEEIYKDRDSQIAAIEKTFEDAQKSISQHYSKPRVTPVEVLPVFPDFKMWINPCAQVIFDSDPAPKDVSAPAGVDMMSQAMIRGMMDEEGNQFVAYFLPNEDTMRKRKRDVEEELDYMPEEVYEYKIAREYNWNVKNKASKGYEENYFFIFRDADGVYYNELETRVRLSKRRAKVGAQSSTNAVLVCKHRDMNEKELEAQEARKAQLENHEPEDEEEELDLEKDMQEDSGEEREKPSDSENSESESEREEEERPADEDEEEEEDEESVKRRRERKSSGSESGDDRQARDEEEIFGSDDDSEEEEEEEEEGGARRRSNSSSVQHSASERASDSSDASDSD
What is the function of this protein?
Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II.  PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity).  PAF1C seems to be required for multiple steps in cardiac formation.  Involved in the migration of myocardial precursors to the midline and the differentiation of the atrioventricular boundary in the developing heart.
What are the official names of this protein?
RNA polymerase II-associated factor 1 homolog, PD2-like protein.
What is the protein family that this protein belongs to?
Belongs to the PAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPB_METM7
Sequence: MVKVAVTGALGRMGSGIIKTITETDGLDVVAAIDIPNHPKKGQDIGELTGLGKIGVSLSTSDELEAILKESGAEVLVDFTAAAPCVNTAKTAAKLGVNLVIGTTGFTPEQRAEMENAISENKVAATISQNYAVGVNIFFKTLELLAQKLGDYDIEILEMHHKFKKDAPSGTALRAAEIIQNNLNRDSNIIYGREGITGERTKEEICIHALRGGDIVGDHTVIFTTDGERLELSHRVTSRQSLVSGAIRAIQFVADKKEGIYNTFDVLDLN
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YXKH_BACSU
Sequence: MKRLFLSIFLLGSCLALAACADQEANAEQPMPKAEQKKPEKKAVQVQKKEDDTSAWIKTEKPAKLPILMYHSISSGNSLRVPKKEFEAHMKWLHDNGYQTLTPKEASLMLTQDKKPSEKCVLITFDDGYTDNYQDAYPVLKKYGMKATIFMIGKSIGHKHHLTEEQMKEMAQHGISIESHTIDHLELNGLTPQQQQSEMADSKKLFDNMFHQQTTIISYPVGRYNEETLKAAEKTGYQMGVTTEPGAASRDQGMYALHRVRVSPGMSGSAFGAYIESMK
What are the official names of this protein?
Putative polysaccharide deacetylase YxkH.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL7_PARDP
Sequence: MADLKKLAEEIVGLTLLEAQELKNILKDEYGIEPAAGGAVMVAGPAAGPAEAAEEKTEFDVVLVDAGANKINVIKEVRGITGLGLKEAKDLVEAGGKVKEGASKADAEEMKKKLEAAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RECO_XANOM
Sequence: MLIEHERGFVLHVRAWRETSLLVEVLTEQHGRVGLLARGVHGPRKQALRAALQPLQLIQFSAVQRGELAQLRQAEALDTAPRLVGDTMLAGFYISELLLRLAPRNDPVPELYACYTQARTHLAADLPLAWGLRRFERDVLEGLGFAFDLQHDSDGQPIDPAARYRLDPEEGALRVLSERLAQDRRETVTGAALLALGEDVMPAAEDMPGLRRSMRSVLLHHLGGRGLKSWEMLEDLARRR
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PRMC_MESFL
Sequence: MMNNVRKLKHNYKIMNNANIKIALDFLLENSKIGKSDAIEIISFITKIEYSEVLFSQEKVLNKKQFKKIIKISKKLAKGKPLAYILGYKIFRTHKILVNKNTLIPRMETELIVDYVNEFINSQNEKISVLDLCCGSGCIGISIAIENKDKMENVTFSDISKKALNITSKNIENNNLVNWTKVVKSDFLNSIIKQQNKFNILVCNPPYIDFNDVDVDKMTKKYEPKLALFAKDNGLFFYKEAIKNIDKFMDITKNILIVFEIGWKQEKELDVFLKQELGLKYKWKFEKDYFNNLRYLILTK
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: YHJB_BACSU
Sequence: MNAALIIIFGVLLLSIFLGIRAQKGKDMNLEQWTVGGRGFGTVFVFLLMAGEIYTTFTFLGGSGWAYGKGGPAFYIIAYGCLAYILSYWLLPAVWTYAKQHKLMSQSDFFTKKYNSPLLGILVSLVGIAALIPYLVLQLKGLGLIVSETSYGKITPTAAIWIGAVSITVYVMVSGIHGSAWISVVKDIMILVVVLFLGVYLPIHYYGGFQDMFQQIETAKPGFLTLPESGQSVAWFSSTVLLTALGFYMWPHTFSASYSAENPKVFRKNAIIMPLYQLVLLFVLFVGFAAILQVPDLNGADGDLSLLRLSLQAFDPWFVGIIGAAGLLTALVPGSMILMSASTLFAKNVYKVIAPRTTEQQVSALAKFLVPVIALISVYFTFKGGNTIVTLLLMGYSLVTQLFPALLFSLLKHNMVTKQGAFAGIIAGVGAVTYITMTETTIGTLFPALPQAAKDLNVGIVALLLNITVMMAVSLMTRKAKSAAADQAA
What are the official names of this protein?
Uncharacterized symporter YhjB.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GYRB_PROMI
Sequence: MSNTYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGYCDEIIVTIHSDNSVSVRDDGRGIPTGIHEEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSEKLELTIHRDGKIHQQIYRSGVPDDRLKVIGETDKSGTFVRFWPSLDTFKGETEF
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_PHOPR
Sequence: MSLVTTINWEKVDGLVPAVIQDNTSGQVLMLGYMNKEALNKTLETKQVTFWSRTKERLWTKGETSGNVLELKSINLDCDQDTLLVKVNPVGPTCHLGTPTCFDNDAEGKQEQPALVFLHQLEQVLANRKGADPESSYTASLYARGTKRISQKVGEEGVEVALAATSGDKAELVCESADLIYHLIVLLQDQGLSLSDVTEKLQERHNK
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_PECCP
Sequence: MNLISIPALQDNYIWLLSNKENRCVIVDPGEASPVLDALAQHALFPEAILLTHHHNDHVGGVHELLKHYPNLPVFGPKETAKCGATSLLEEGNTVSLLNSEFSVIEVPGHTSGHIAYYNAPFLFCGDTLFSAGCGRIFEGTPRQMYESIQKIAVLPDDTVICCAHEYTLSNLRFSNAIWPEDQSIEAYLHEISQIREKSQSSLPTTLGLERRINLFLRCHELDLKRKLSKEPENIENWQVFEMLRSKKDCF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.