PharMolix/UniProtQA huggingface dataset:
Protein: RS18_CAUVC
Sequence: MTDTTAPEAGAPAAAAGGARRPFFRRRKVCPFSGANAPKIDYKDVKLLQRYVSERGKIVPSRITAVSAKKQRELAKAIKRARFLALLPYVVK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SIX3B_LEIHE
Sequence: MKLLLLLTISASMLIEGLVNADGYIRGGDGCKVSCVINHVFCDNECKAAGGSYGYCWGWGLACWCEGLPADREWDYETNTCGGKK
What is the function of this protein?
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and block action potentials, primarily by depolarizing the axonal membrane and suppressing the sodium current.  This depressant toxin is active only on insects.  It is found in a relatively small amount in the venom, and its activity on insects is 10-fold higher compared to other known depressant toxins.
What are the official names of this protein?
Beta-insect depressant toxin Lqh-dprIT3b.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: XYLA_PRIM3
Sequence: MVQTSTNKINHFESANKVLYEGKDSKNPLAFKYYNPEEVVGGKTMKDQLRFSVAYWHTFTADGTDPFGAATMQRSWDRYDGMDLAKARVEAAFQLFETLNVPFFAFHDRDIAPEGSTLQETNKNLDVIVTMIKEYMQTSNVKLLWNTANMFTNPRFVHGAATSCNADVFAYAAAQVKKGLETAKELGAENYVFWGGREGYETLLNTNLQLELDNLARFMHMAVDYATEIGYTGQFLIEPKPKEPTTHQYDTDAATTISFLRQYGLDKYFKLNLEANHATLAGHTFEHELRVARVQGLLGSVDANQGDPLLGWDTDEFPTDLYSTTLAMYEILQNGGLGSGGLNFDAKVRRGSFEQDDLLYAHVAGMDAFARGLKVAHKLVEDRVFENVINERYSSFKEGIGLEIVEGKANFHTLEQYAFKNPNIANKSGRQERLKSILNQYILEV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPT_HAEIN
Sequence: MISQIDKTELLERFLHYVSFHTQSKPNAKHSPSSVGQMKLAMQLQKELIQLGLENVEVSKYAVVTAFLPANDPNLTKTIGLVAHLDTSPQCSGKNVRPEVIEEYRGGDIALGIGEEFISPVYYSFMQKLVGQTLIVTDGTTLLGADNKAGIAEIMTALSILQKENIPHCNIRVAFTPDEEIGLGIHYFPMEKFSCDWAYTIDGGEVGELEYENFNAATAKVRFFGRNIHTGYAKGKMLNALTLACEFQQVFPVDEVPEKTDGKVGFYHLEDFSGDIEQVELTYLIRDFDEQNFAQRKAFIKNQVEKFNAKKGLKKPIELEIQDSYQNMYDVVKNVPQSIELADRAMKAVGIKPNHKPIRGGTDGAFLASKGLACPNIFTGGYNFHSKHELVSLQGMENTVQVIIEMLKCKDL
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_PHEZH
Sequence: MASLKEMRNRIGSVKATQKITKAMQMVAAAKLRKAQDAAQNARPYAQRMASVIANLAAGVSGDGAPKLLAGTGSDRRHLVVVATSDRGLAGGFNSAIVRAARERINALSAEGKDVRVITIGRKARDQLRRLAGERLVATYEAGSNPSLAVAEEVSARIQEMFEAGEVDVVHLVFSSFKSVVTQQPTVRQLIPAEVAAGQAPLDLKGATYEYEPDEEQILETLLPRNVTTQLLSATLENQAGFYAAQMTAMDNATRNAGDMIASLTLQYNRSRQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TDCC_ECO81
Sequence: MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SC61G_ENCCU
Sequence: MSQKLQKPSFLSEYLRSIRLFSKKCVRPSGKELSMSIKRHAIGIGFLGILGYAIKLIHIPINNIIVSSPGKE
What is the function of this protein?
Necessary for protein translocation in the endoplasmic reticulum.
What are the official names of this protein?
Probable protein transport protein Sec61 subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: CIP4_PONAB
Sequence: MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAVDPKNDSQVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSLGTPSDGRPELRGPGRSRTKRWPFGKKNKPRPPPLSPLGGPVPSALPNGPPSPRSGRDPLAILSEISKSVKPRLASFRSLRGSRGTVVTEDFSHLPPEQQRKRLQQQLEERSRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQITETLSNIERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHARPPDPPTSAPPDSSSNSASQDTKESSEEPPSEESQDTPIYTEFDEDFEEEPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYLRVTLN
What is the function of this protein?
Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis.  Also acts as a link between CDC42 signaling and regulation of the actin cytoskeleton.  Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules.  Also enhances actin polymerization in the vicinity of membrane tubules by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex.  Actin polymerization and dynamin may promote the fission of membrane tubules to form endocytic vesicles.  Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells.  Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling.  May be required for the lysosomal retention of FASLG/FASL (By similarity).
What are the official names of this protein?
Cdc42-interacting protein 4, Thyroid receptor-interacting protein 10, TR-interacting protein 10, TRIP-10.
What is the protein family that this protein belongs to?
Belongs to the FNBP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Golgi apparatus. Cell membrane. Cell projection, phagocytic cup. Note=Localizes to cortical regions coincident with F-actin, to lysosomes and to sites of phagocytosis in macrophages. Also localizes to the Golgi, and this requires AKAP9. Translocates to the plasma membrane in response to insulin stimulation, and this may require active RHOQ (By similarity).
Protein: LPXH_SHESM
Sequence: MRTLFIGDLHLSADRLDITKAFNRFLDTELDDADALYILGDLFEVWVGDDLAAPFALELARRLKQISQRLPIYFIHGNRDFMLGKQFTDAAGMQMLPEVTCLDLYGVSTVILHGDSLCTLDKAYQRFRKLRSFAFARWLYSCLPKRKRQAIANKIRSNSQSSNQQKSYVIMDVEPSAVDALFAQTHCKQMIHGHTHRPAIHNFTNGCKRIVVGDWYEQGSVLVVSADGVDLKSLPFDAS
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HIS3_BORA1
Sequence: MSTEPDWMADVVFDADGLIPAIAQDAENGQILMVAWMNRESLAETAATGRAVYWSRSRKKLWRKGEESGHAQQVHELRLDCDGDVILLKVHQNGGIACHTGRASCFYRRLDGTSQRAAWVTVDPVLKDPELIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_PHOLL
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVNDGIIRIHGLAEVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGPVEHDGFSAVEMIAPGVIDRQSVDQPVQTGYKSVDAMIPIGRGQRELVIGDRQTGKTALAIDAIINQRDSGIKCVYVAVGQKASTIANVVRKLEEHGALANTIVVVATASESAALQYLAPYSGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEKFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNAGIRPAVNPGISVSRVGGAAQTKIVKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLSLFSAERGYLEDIEIAKVIDFESALLAYANREHADLLKEIDQSGGYNEEIEAKLKALLDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CARB_PAEAT
Sequence: MPKRTDLKSVLVIGSGPIVIGQAAEFDYSGTQALRVLKEEGLRVILVNSNPATIMTDPEFADATYVEPITPEVVEKIIAKERPDAILPTLGGQTALNTAIALDKNGVLEKYNVELIGANIAAIELGEDREKFKGVVERCGAESARSHIIHTMEEAFAAAEDLGYPMVVRPSFTMGGLGSGLAYNEDDLRRIVGQGLQYSPTTEVLLEESILGWKEYELEMMRDKNDNVVVVCSIENFDPVGVHTGDSITVAPALTLTDREYQKLRDVSIAVIREVGVDTGGCNIQFAIDPATGRVVVIEMNPRVSRSSALASKATGFAIAKIATKLSLGYTLDEIPNDITQKTPASFEPTLDYVVVKVPRFAFEKFPAADNTLTTTMKSVGEAMAMGRNFTEALQKALRSLEQKGSQLDFSSVPEYEVAELIEKAKRPTTDRLHQVQRALLGGATVEDLFEATKIDPWFLDQLQLLNETAQEIRKAGVLTEEMLRNAKRHGFSDEQIGALTHNNEAVVRGVRQALGIRPVYKTVDTCAAEFAAYTPYHYSSYDEEDEVGLHAKPSVIILGSGPNRIGQGIEFDYSCVHASMALRKAGYETVMVNCNPETVSTDYDVSTRLYFEPLTLEDVLEVIAAEERTGGVMGVFVQLGGQTPLKLAQQLADAGVPILGTSPEAIDLAEHRGAFARVLDEAGLTSPKNGTAVSFEDAKKIADEIGYPVLVRPSYVLGGRGMEIVYDEANLSRYIANATEITPDHPVLIDRFLEDAVEIDVDALFDGTDMYLGGIMEHIEEAGIHSGDSACVLPPITLGNNVIERVRTATRAIAEGVGVRGLINIQFALASDVLYVLEANPRASRTVPFVSKATGVQMAKAAALIGTGVTINQLRGAYKMLPETGDGSTLPLDAPVAVKEAVLPFSRFRTPEGKVVDSLLGPEMRSTGEVMGIDKHFDTAFAKSQAAANNALPTEGKIFVSVANRDKRSVIMGVKRLSDLGFEIVSTGGTADVLRRNGIQATPVRKVAEGSSAEGEGTIADLVIAGEIDMVFNTPSGGEARSDGYELRAAATSIGIPCITTVAEFNAAVQAIEALRTYEWSVTSLQEHAANLSAAMEAANA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: PGP_SULAC
Sequence: MIRLILTDVDGTLTFDRDTYNIDLDAVDLLRKVEKKGIKVGLVSGNSYPVLRALYTYFGFNGGIVAENGCIVYYDNQLKEVCERVERSLISEFENRFGVKGSWQNQFKVCDFSFYPPILKDEMVKWALDKGLYIKTSGYAVHISKSKRGKAEGVRELIKMHGLDKAEVVGIGDSSTDIEFLEEVGIRVVVGNADESLKSIGDFVMREKSGKAVVEFIKKVITGEINE
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: DPOL_HBVB8
Sequence: MPLSYQHFRKLLLLDDEAGPLEEELPRLADEGLNHRVAEDLNLGNPNVDIPWTHKVGNFTGLYSSTVPVFNPEWQTPSFPDIHLQEDIVDRCEQFVGPLTVNERRRLKLVMPARFYPKVTKYLPLDKGIKPYYPEHVVNHYFQTRHYLHTLWKAGILYKRESTHSASFCGSPYSWEQDLQHGRLVIQTSKRHGDKSFCPQSPGILPRSSVGPCIQSQLRKSRLGPQPTQGQLAGRPQGGSGSIRARVHPSPWGTVGVEPSGSGHTHICASSSSSCLHQSAVRTAAYSLISTSKGHSSSGHAVELHHFPPNSSRSQSQGPVPSCWWLQFRNSKPCSEYCLCHIVNLIDDWGPCAEHGEHRIRTPRTPARVTGGVFLVDKNPHNTTESRLVVDFSQFSRGNTRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSNSRIINHQHGTMQDLHNSCSRNLYVSLMLLYKTYGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSALCSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLYAAVTNFLLSLGXHLNPHKTKRWGYSLNFMGYVIGSWGTLPQEHIVQKIKLCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALKPLYACIQAKQAFTFSPTYKAFLRQQYLNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGTFVSPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLLRLPYRPTTGRTSLYAVSPSVPSHLPDRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: RR4_MARPO
Sequence: MSRYRGPRVKIIRRLGALPGLTNKTLKLKSGYINQSTSNKKVSQYRIRLEEKQKLRFHYGLTERQLLKYVRIARKAKGSTGQVLLQLLEMRLDNIIFRLGMAPTIPGARQLVNHRHILINNNTVDIPSYNCKPKDVITIKDRSKSQSIIIKNLNSFQKQKIPNHLTFDLMQIKGLVNQIIDREWIYLKINELLVVEYYSRQV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECO_VIBCH
Sequence: MSDGLQRCFVLHRRPYSESSLILDVFSEEYGRVTLMAKGARGKRSNLKGALQPFTPLLLKWSGNGSMKTLRQAEPISLGLPLSGVYLYSAMYINELVDRVLMPEVASPGLFHDYLFALTELAQSTNPEPALRRFELALLAAMGYGVDFLHCAGTGEPVSPDMTYRYREQKGFIASVRRDNLTFLGNELIAISERRFTSKEQLQAAKRFTRLALKPYLGGKPLKSRELFRQTTLPRARSTEE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: HIS5_MYCLE
Sequence: MRSKSVVVLDYGSGNLWSVQRALQRVGAAVEVTADSAAGAAADGLLVPGVGAFEACMAGLRKIAGERTIAERIVAGRPVLGVCVGMQILFARGVEFGVETTGCRQWPGVVTRLDAPVVPHMGWNVVDSASGSALFKGLDAGVRFYFVHSYAAQRWEGSSKALLTWATHQVPFLAAVEEGPLVATQFHPEKSGDAGATLLSNWLGEL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T3HPD_PARDP
Sequence: MRTSRVVHVVSCHAEGEVGDVIVGGVAPPPGETVWDQSRWIARDETLRNFVLNEPRGGVFRHVNLLVPPKDPRAQMGWIIMEPADTPPMSGSNAICVATVLLDTGIIPMQEPITRMVLEPPGGLIEVEAECRGGKAERIRVRNVPSFADRLDARIEVEGLGTITVDTAYGGDSFVLVDAASVGMRIAPDQARDLAEMGVRITRAANEQLGFRHPANDWSHISFCQFTDPLSERDGVLYGRNAVAIRPGKIDRSPTGTGCSARMAVLHARGRMKPGDRFVGRSIIDTEFHCSIADEVELNGKRAIRPIISGRAWVIGTKQLMVDPDDPFQNGYRLSDTWPMDL
What is the function of this protein?
Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C).  Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which would allow P. denitrificans to grow on t3LHyp as a sole carbon source.  Displays neither proline racemase activity nor 4-hydroxyproline 2-epimerase activity.
What are the official names of this protein?
Trans-3-hydroxy-L-proline dehydratase, T3LHyp dehydratase, t3HypD, Trans-L-3-hydroxyproline dehydratase.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: MUTL_SPHAL
Sequence: MSIRRLPETLVNRIAAGEVVERPAAALKELVENAIDAGATRIAVRIAEGGIARLEVEDDGCGMTAADMVLALERHATSKLPDDAIEAVTTLGFRGEALPSIASVARLTLESRTAGGDGWRRVVDNGAVVAEGPAALGQGTRVIVEHLFARVPARRKFLRSARSEYAACLDVVRRLAMARPDVGFTLEHDGRRVLDVQGGQDRVGRVAALTSRDLAANSIGVDLDRGEVHLGGVISLPTYNRGIADHQYLFVNGRPVKDRLLVGALRGAYADLLARDRHPVVALFLDVPTGEVDVNVHPAKTEVRFRDPQLIRGMIVGGLRRALDEHGFRSVQKPAEAALAAWQQEPVAPPPATGFLFDRRAGAAVHPFAAEVSLPAADVARVYDRLMPFTAPAPLAGRAEVAATPPPAAEAHPLGIARGQIAKTYIVAEAEDGLVIVDQHAAHERLVLETLKRGMAGQAVPSQGLLIPEVVELDEPACDRLEAAADGLAALGVELERFGPGAVMVRATPAMLGAIDCHRLVTDIADDLAGYDAALGLNERLELVAATMACHGSVRAGRTLSVAEMNALLRQMEVTPHSGQCNHGRPTWVKLAMGDVERLFGRK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: CYT1B_ARATH
Sequence: MSQQPPAVGVPPSHAYPAEGPPKDAYPPPGQPYPQQGYPPPQGYPQQGYPPQGYPPQGYPEQGYPQQGYPPQQQQQQKHSPGMLEGCIAALCCYCVLDACF
What are the official names of this protein?
Cysteine-rich and transmembrane domain-containing protein B.
What is the protein family that this protein belongs to?
Belongs to the CYSTM1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FTSZ_AQUAE
Sequence: MEEFVNPCKIKVIGVGGGGSNAVNRMYEDGIEGVELYAINTDVQHLSTLKVPNKIQIGEKVTRGLGAGAKPEVGEEAALEDIDKIKEILRDTDMVFISAGLGGGTGTGAAPVIAKTAKEMGILTVAVATLPFRFEGPRKMEKALKGLEKLKESSDAYIVIHNDKIKELSNRTLTIKDAFKEVDSVLSKAVRGITSIVVTPAVINVDFADVRTTLEEGGLSIIGMGEGRGDEKADIAVEKAVTSPLLEGNTIEGARRLLVTIWTSEDIPYDIVDEVMERIHSKVHPEAEIIFGAVLEPQEQDFIRVAIVATDFPEEKFQVGEKEVKFKVIKKEEKEEPKEEPKPLSDTTYLEEEEIPAVIRRKNKRLL
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: NDUA3_PANTR
Sequence: MAARVGAFLKNAWDKEPVLVVSFVVGGLAVILPPLSPYFKYSVMINKATPYNYPVPVRDDGNMPDVPSHPQDPQGPSLEWLKKL
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3, Complex I-B9, CI-B9, NADH-ubiquinone oxidoreductase B9 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA3 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RS16_CITBB
Sequence: MAIKIRLARAGAKKKPFYQVVVADCRCRRDGRFIENVGTYDPNKNPAVYNLEEGKTLEWLGKGAQPTDTVKQILKKVGIWEKFVSPAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RUVC_CHRVO
Sequence: MSRRILGIDPGSLITGFGVIDVVGNQRHYVASGAIRTKSGSPLAERVKVLVDGIHQVIDTYRPTEAALERVFVNVNPAATLMLGQARGACMTALVLKDLPVAEYTALQVKQSVVGQGKAPKEQVQYMVVRMLNLSGTPQADAADALAVALTHANHSGGAIGKLALRGLKVRGGRLV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ISCA_ECO8A
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: SLD7_ASHGO
Sequence: MASDWDKWFELRLAVGRGVVLRDVQLWQRRGSSSSRPASHTGLTGRLLQAISLDRLPVWAGRSNSYRCFSSSTTTRAFFAAKLLRRRHRARGLVVELAPTRASKEYLIFHKELGADSHFELCCFTLDLSRKHALDAALKPVLPAARIDTLVLRSGARRRAAENRQDPANTSDARQRFVARLSQCILGGLRLRAVPQARYEKLYRAVFQASEFAFRDELAASADVPFEALQDCVETLLKLFTRS
What is the function of this protein?
Required for the proper initiation of DNA replication.  Required for mitochondrial morphology (By similarity).
What are the official names of this protein?
Mitochondrial morphogenesis protein SLD7.
What is the protein family that this protein belongs to?
Belongs to the SLD7 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle pole.
Protein: 17KD_RICRH
Sequence: MKLLSKIMIIALAASMLQACNGPGGMNKQGTGTLLGGAGGALLGSQFGKGKGQLVGVGVGALLGAVLGGQIGAGMDEQDRRLAELTSQRALETAPSGSNVEWRNPDNGNYGYITPNKTYRNSTGQYCREYTQTVVIGGKQQKAYGNACLQPDGQ
What are the official names of this protein?
17 kDa surface antigen.
What is the protein family that this protein belongs to?
Belongs to the rickettsiale 17 kDa surface antigen family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.