PharMolix/UniProtQA huggingface dataset:
Protein: NARB_SHEFN
Sequence: MSVVQSSCAYCGVGCGVSVSSNKPNWTDVDAADLILVGDNKHPANYGHLCAKGERLLDSLAQPNVLRYPKLRSGMPLDWDKASTLIADTFAKTIAEHGPDSVALYLSGQLLTEDYYVANKFAKGFLKTANVDTNSRLCMSSAVSAMQRAFGEDVVPGCYDDLEQADVIVLVGANTAWTHPVLFQRILAAIKANNAQLVVIDPLSTATAKQADLHLAIKPGADLTLFHGLLGYLADQNRVDHAYIAAHTEGFDTVVLQAQQLSANLADLATQVGVSVTQLTQFYQLVANNKKVLTASCQGVNQSTIGTDATNAMINCHLALGHIGQAGCGFFSLTGQPNAMGGREVGGLATQLACHMGFSQPEQQLLADFWKVDSIADQKGLVAVEMFDALAEGKIKAIWIMGTNPVVSLPNSEKIAQALADCPFVVVSEISPDSDTAKLADVLLPAQGWSEKCGTVTNSERTITRQRGFITAKGQAKPDWWAVSQVAKKMGFDGFEFDDNASIFSEFAALSAKVKQVFPTKVFDLTGLTELSKAQYDALAPTQWPIASATQIGQQNVRVFGLGEFATATGKAQFVTPAVVSVPQQSLPSNTLLLNTGRSRDQWHTMTRTGHIASLRASIPEPVVHLHSSQLSALSLTEGGLVRIEAIQNQIEQYSTETANPDLFTHASFTMARAVVDDDIPTNMALMSMHWSAQFSLTKGVNQALDARVDPISKQPGFKCQPVTLTPVELALQGVVFGQHYSSAHGLCWQVAQTLENGVCHHIGFTDTDDGFAYQATVHSLKWTLTVVGQPLYIQCNMDKGLLKALKVLSHTQVNVALYQMNDFIGKPVDKQLIKQLHQQIKAGNSPLICACTGVTEANINDEINQQFNDQVMSDGLANISFEQALDSTQLLLGCGRQCGSCHSEVKQCAKQSWKDALSYCESYSDIDHQPSVAEDVA
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y914_AQUAE
Sequence: MKRMAGVLGVVLGVFALFGSGKSVDYGDWCPKGKSLGKDIYVEGIVDYEGKNWCKVVVRTPYSVTEVYYTPDGSGEKVVKYKNGKKMAEIELVENQVYLRLYDKNGKVVEEIKSREEF
What are the official names of this protein?
Uncharacterized protein aq_914.
Protein: RL1_CHLAB
Sequence: MTKHGKRIRGILKSYDFSKSYSLQEAIDILKQCPPVRFDQTVDVSIKLGIDPKKSDQQIRGSVSLPHGTGKTLKILVFAAGEKAKEALDAGADFVGSDDLVEKIRGGWVDCDVAVATPDMMREVGKLGKVLGPRNLMPTPKAGTVTMDVTKTIAELRKGKIEFKADRAGVCNAGVGKLSFDGHLLKENIETLCSALIKAKPPAAKGQYLVSFTVSSTMGPGISVDTRELMAS
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: BIOF_SALEP
Sequence: MSWQQRVDDALTARRATDTLRRRYVVSQGAGRWLVANGRQYLNFSSNDYLGLSQHPQIIRAWQQAATRFGVGSGGSGHISGYSVAHQALEEELAQWLGYPRALLFISGFAANQAVITALMKKNDRIVADRLSHASLLEAANLSPAQLRRFIHNDTQHLSRLLQSPCVGQQLVVTEGVYSMDGDSAPLAEIQHIARRHHAWLLVDDAHGIGVTGDEGRGTCWQRGVKPELLVVTFGKGFGVSGAAVLCSESVADYLLQFARHLVYSTSMPPAQAQALSASLAVIRSDEGRERREKLAALVQRFRAGVNASRFTLLNAHSAIQPLIVGDNSRALRLAEALRQQGCWATAIRPPTVPVGTARLRLTLTQAHEACDIDRLLEVLHGAGE
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: ACCD_CLOBK
Sequence: MLKNLFRKTKYITVSQKNIENYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLCGNHFRIGVKERIKYLFDKDTFKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGKGKIAGMEAVVCIMDSKFMMGSMGCVVGEKITRAIERAIKLRLPVIIFTASGGARMQEGILSLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRVIEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_SALRD
Sequence: MAEGTEVVARNKKAQFEYDIEETLEAGLVLEGSEVKSVRQGKASLDGAYCQVDREGEMKIHGMYIKPYEEAGPFGHEPRRNRKLLLHDQQIGKWGQMAEQEGYTIVPLSLYFRDGWAKLKIGIAKGRQKHDKRQAIKEREMERRLEREQSDYNF
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SYC_PYRHO
Sequence: MTLRIYNTLTKQKEEFKPINEGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHKGYSVLMVMNFTDIDDKIIRRAKETGEDPAKLAEKFIKVFLEDMKALKVKPADIYPRVTEHIEDIIQFIERLKEKGYAYEGSDGVYFEVQKFKEYGKLSGVKLEELRKGARVEPGEGKKNPEDFALWKKAKPGEPKWESPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHEWVHYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRFFVLQKHYRSPLDYSEEGLQHAKNNLERLYNTLENIRIAMENAELAYTWDENDFKAYNSIKEARRKFYEAMDDDFNTAEALKAVFEVSNAINKYITEAEKPKESVLRKAWEFFRTVGEIFGIFEEYFKEEKAKEEEKLIELLIQVRAELRKERKFELADKIREELRKLGIQLEDKGKETIWKRIKV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAHD_PSEU8
Sequence: MLLCRLLFLECLIVIVDFYFDFLSPFSYLANHRLSKLAQDYGFSIRYYAIDLARVKIAIGNVGPSNRDLIVKLDYLKVDLQRWAELYEIPLVFPANYNSRRMNTGLYYSGAMAQTGAYVNVVFNAVWGDGIAPDLESLPALVSEKLGWDRSAFEDFISSDAATERYDEQTHAAIERKVFGVPTMFLGDEMWWGNDRLFMLENAVGGAPVNGE
What is the function of this protein?
Involved in the naphthalene catabolic pathway.  Catalyzes the reversible glutathione-dependent isomerization of 2-hydroxychromene-2-carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA) (Probable).
What are the official names of this protein?
2-hydroxychromene-2-carboxylate isomerase, HCCA isomerase.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. NadH family.
Protein: ZN536_HUMAN
Sequence: MEEASLCLGVSSAEPEAEPHLSGPVLNGQYAMSQKLHQITSQLSHAFPELHPRPNPEEKPPASLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKEALGKLLSPISSMAHGVPEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSKEHPLQRNHEDTLANAGVLFDKEKREYVLVGADGSKQKMPADLVHSTKVGSQRDLPSKLDPLESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQDHKDEMSSKASLFIRPDILRGAFKGLPGIDFRGGPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEIGRAYQSIVSNGVNFQGSLQAFMDSFVLSSLKKEKDMKDKALADPPSMKVHGVDGGEEKPSGKSSQRKSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHLQANHLGKAKRKDNTIGVTVNCKDQAREASKMALLPSLQSNKDLGLSNMISSLDSASEKMAQGQLKETLGEQKSGAWTGHVDPAFCNFPSDFYKQFGVYPGMVGSGASSSCPNKEPDGKAHSEEDVPILIPETTSKNTTDDLSDIASSEDMDSSKGENNDEEDVETEPEMMTKPLSALSKDSSSDGGDSLQPTGTSQPVQGLVSPLSQAPEKQWHSQGLLQAQDPLAGLPKPERGPQSLDKPMNMLSVLRAYSSDGLAAFNGLASSTANSGCIKRPDLCGK
What is the function of this protein?
Transcriptional repressor that negatively regulates neuron differentiation by repressing retinoic acid-induced gene transcription (PubMed:19398580).  Binds and interrupts RARA from binding to retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (PubMed:19398580).  Recognizes and binds 2 copies of the core DNA sequence 5'-CCCCCA-3' (PubMed:14621294).
What are the official names of this protein?
Zinc finger protein 536.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FSHR_MESAU
Sequence: MALLLVSLLAFLGSGAGCHHWLCHCSDRVFLCQDSKVTEIPPDLPRNAIELRFVLTKLRVIPQGSFSGFKDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIERANTLLYINPEAFQNLPNLRYLLISNTGIKHLPVVHKIQSLQKVLLDIQDNINLHTIARNSFMGLSFDSLILWLNKNGIQEIHNCAFNGTQLDELNLSDNNNLEELPNDVFRGASGPVILDISRTKVHSLPSHGLENLKKLRARSTYSLKKLPSLDKFVTLVEASLTYPSHCCAFANWRRQISELHPLCNKSVLRQDIDYVTQARDQNTSLIDDDLSYGKETDMMYSEFDYDLCNEVIDVTCSPKPDAFNPCEDIMGYNILRVLIWFISILAITGNITVLVILTTSQYKLTVPRFLMCNLAFADLCIGIYLLPIASVDIHTKSQYHNYAIDWQTAVGCDAAGFFTAFASELSVYTLTAIPLERWHTITHAMQLERKVQLRHAASVMVMGWVFAFAAALLPIFGVSSYMKVSICLPIDIDSPLSQLYVMALLVLNVLAFVVICGCYTHIYLTVRNPNIVSSSSDTKIAKRMATLIFTDFLCMAPISLFAISASLKAPLITVSKAKILLVLFYPINSCANPFLYAIFTKNFRRDFFILMGKFGCYEMQAQIYRTETSSTAHNFHSRKGHCPSAPRVTNSSSYMLVPLSQSAHN
What is the function of this protein?
G protein-coupled receptor for follitropin, the follicle-stimulating hormone.  Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
What are the official names of this protein?
Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GNAT9_ARATH
Sequence: MVTRMATKVSLEGKRVVLVPYMAEHVPKYHQWMQDSALLEATGSEPLSLEQEYEMQLSWTQDPNKRTFIVLDKDFVKGDLAHGQPHVEAMTGDVNIYMNDVDDPKVAEVEIMIAEPRSRGKGLGKESVLIMMAYGVKNLEIHKFTAKIGESNTASLSLFRKLGFEESSYSGIFKEVTLEYPVTNLRREELLKLLDEVIRHTHSSNNPSDSLLSGEATA
What is the function of this protein?
Probable protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA) and epsilon-lysine acetylation (KA).
What are the official names of this protein?
GCN5-related N-acetyltransferase 9.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
Protein: SHO1_KLULA
Sequence: MALIKASQARAVRENPHVSHQFNISSFLGDPFAIGTLSIALISWIIALAGSIAVAASTSPFPRFSWWTIVYEILLMITLFIVYCLDLVDYYRMFITCAVGIAFVYTSNSTNSIVYYEGSKSGAAAAGFILLSMINLVWVIYFGGDNASPTNRWIDSFSLRGIRPSVLETSMAIARSQRLPVKPSYPYQYQEDLRSASLPDVHHDDEGEGHSGNMYAPELQSSTKYVSSTVLNGFENTDHSSSKPNLDVNAQNTATLNTQATGTFITDTTNANTDTTMGDTLGLYSDIGEELNSFPYTAEALYTYQADQTDAYEISFEQGEILRVGDIEGRWWKAKKSNGETGIIPSNYVKLLDGKSH
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIC8_YEAST
Sequence: MDDARLFRRVVCMPFPMIMLVALYRNVLGRDSTVDCSFDVILTPWIMASMFSKRMVNWSNPRQAVLKVCSAAVTSRIVANWLFTMNILYTSGEKGFYSLATAVVIKTVTDGFTVIRVFSIHLNESVYSKPLP
What are the official names of this protein?
Putative uncharacterized protein YIL028W.
Protein: GLND_NEIMB
Sequence: MPANLSSALETFKQQRDAAEAHYLKANRVSVFFREYTAAVETLLAALWAEYFQNSALCLMAVGGFGRGELYPCSDVDLAVVSPAPLSDGIQEQIARFVQTLWDCKLMPSVKSGSVDELCESVRNDITGDTAFLEARFLFGNRQTVDKLAEKMNAQRNVAAFVEAKLVEMEHRHAKSQGSGAVLEPNIKSCPGGLRDIHTLLWIAKAQGLATDLPDLLKQRILTRAEAGMLSHGYRRLAHIRIHLHLNAKRAEDRLLFDLQPQVAESMGYEGLNLRRQSEELMRVFYRAIKTVKQLGGILTPMLQSRVSSTPLRVTLRIDDDYIQVNNQIAARHTDIFFRRPEHIFKIVEIMQQRNDITALEPQTLRAWWGATRKINRSFYQNPENRRRFAGFFRNGNGLTQTLRFLNLYGVLGRYLPAWEKIIGLLQHDLFHIYPVDDHILTVVRNVRRLALDMHSHELPYASALMQSFEKQDILYLAAFFHDIAKGRGGDHAIQGIADARQFAADHFLTGEESDLLAWLVENHLLMSAVAQKEDIQDPSVLDAFCKRVQTHERLSALYLLTISDIRGTNPKLWNAWRASLLESLFHAAGRYLTGNGGNPHTLFGRRRQEAADLLTRAAVPEKQQKKLWNALGSAYFARHQSREILWHAANLVHDFETPIVRSRILPKSDSFQVMVFMPNGPRLFARLCRIFSRHGFDILAARAFITEHDYILDTFIVQIPSQHAPEDYPDIQSALEAELNSFIHGHTVAETQSRSRRISRRSRYMPIAPSITITPEEDYPDWYSVEITAVNRPFLLADMAEVFFAHNVSLRYAKISTLDERAEDSFTVFSPDLKNPKIQSSLKQTLLEQLS
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: NUSB_MYCBP
Sequence: MSDRKPVRGRHQARKRAVDLLFEAEVRGISAAEVVDTRAALAEAKPDIARLHPYTAAVARGVSEHAAHIDDLITAHLRGWTLDRLPAVDRAILRVSVWELLHAADVPEPVVVDEAVQLAKELSTDDSPGFVNGVLGQVMLVTPQLRAAAQAVRGGA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: TCP24_ARATH
Sequence: MEVDEDIELQKHQEQQSRKLQRFSEDNTGLMRNWNNPSSRIIRVSRASGGKDRHSKVLTSKGLRDRRIRLSVATAIQFYDLQDRLGFDQPSKAVEWLINAASDSITDLPLLNTNFDHLDQNQNQTKSACSSGTSESSLLSLSRTEIRGKARERARERTAKDRDKDLQNAHSSFTQLLTGGFDQQPSNRNWTGGSDCFNPVQLQIPNSSSQEPMNHPFSFVPDYNFGISSSSSAINGGYSSRGTLQSNSQSLFLNNNNNITQRSSISSSSSSSSPMDSQSISFFMATPPPLDHHNHQLPETFDGRLYLYYGEGNRSSDDKAKERR
What is the function of this protein?
Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e. g.  miR164).  In association with ABAP1, exerts a negative role in cell proliferation in leaves, possibly by inhibiting mitotic DNA replication.  Participates in ovule develpment (PubMed:25378179).
What are the official names of this protein?
Transcription factor TCP24.
What are the subcellular locations of this protein?
Nucleus.
Protein: VE1_MNPVA
Sequence: MEDLEEGTGEGCSGWFDREAICSDGSSDEEPNESFESIADMFDDGTQTQGNSLELFHTQEKEETRTQIQALKRKYIPSPEAGGDLSPRLRAISITPKKKKPSRRLFETPEDSGNGSLGNETTDTSSGFQVVGDSAVDVCDAGRLLNLNLLQSHNRVARLLAVFKEAYGVSYKELTREYKSDKTCNPDWVIALYSLSEPILNAARTTLQGICEYVFMQSRPTAAATVALLTVRFKCSKSRETVRKQMCGMFHSDPLLCLCDPPKVQSVPAALYWYKSSMYSGTFTHGEAPEWIKRQTMITCAMEETKFDLSEMVQWAYDNNYEDESQIAFEYARTATESPNANAWLASNAQAKHVRDCATMVRHYKRAEMKAMSMSQWVWKCCREEPEEGTWTPISLYLASEGVEVIRFLSAMKSWLRGIPKKNCLVFYGPPNTGKSLFTMSLIKFLRGRVISFANSKSHFWMQPLAEAKVVLLDDATRATWDYVDTYMRNAMDGNPLSIDCKYRTPVQVKCPPMLVTTNEDVHLNDRWRYLHSRIQVFHLKEPMPIDTAGNPEYSFSNRHWKAFFEKLQKPLDLSEDEGDPKDNGEHTQPFSCCARGTDVHV
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PUR7_ALBFT
Sequence: MNTSQPALHTSMLTSLPLLARGKVRDNYAVGIDRILMVASDRLSAFDVIMGEPIPGKGALLTQMALFWFDKLGPKGLNLCPIHLTGDAPESVVTAAEVPQVTGRSMLVKRLKPLPVEAVVRGYLAGSGWKEYQHNGAVCGVKLPAGLQNASKLPEPIYTPAAKAAAGDHDENITFEQTVEMIGLDLATRIRDISIAIYKAASEIARAKGIIIADTKFEFGLDADGTLTLMDEVLTPDSSRFWPAESYQEGINPPSFDKQFVRDWLEQVQVNGKPWNKTPPAPRVPDEVIAKTAAKYQEALTRLIG
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: YQGF_BACCZ
Sequence: MRILGLDVGTKTVGVAISDEMGWTAQGLETIKINEERGQFGFDRISELVKQYDVDKIVVGLPKNMNGTIGPRGEACQQFAENLRELLQLDVVMWDERLSTMAAERLLISADVSRKKRKQVIDKMAAVVILQGFLDSK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_BORDL
Sequence: MAVPKFKPSKSRSRTRRSINMRKKIPQFQECSNCGNLAIRHRICAKCGYYRNSQYLELGL
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: OTC_TRAHI
Sequence: MALSTKVPHLMTLADLTPGQIQRIITHSYHLKRTAQPWLAPQGRAGSGGKYSNAPHKLRMPSQSLFSKSIALLFSKRSTRTRLSAETAALLLGGQALFLGREDIQLGVNETVPDSARVIGGMCQGIFARVGDHSEIEELARYSPVPVLNALSSLWHPTQVLADILTLHEHAALFDPASASPTPSAADAFSQKYTKLGEVRPLTVAYVGDSANVLHDMLVTYPRLGHQLRVASPENDKYRAPKAVWDRVVELGCDKNIFWTADPRAAVKGADLVVTDTWISMGQEAEKAQRLKDFAGYQVTEALCREGGANPDWKFMHCLPRKQDEVDDEVFYGPRSLVFQESDNRKWTIMALFDLLFGKWSLLARNGEGADAGSE
What are the official names of this protein?
Ornithine carbamoyltransferase, mitochondrial, Ornithine transcarbamylase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: THIC_BACP2
Sequence: MKEKKNIPTTQSLLSSFDGSRKVYEKGSRPDILVPKREIALTQTVTQAGMIQNEPIRVYDTSGPYTDEHAHIDVTKGLNRLRAAWVEERGDTESYEGRHVKPEDNGYRSRNGSHQHIHTDFHHKPLRAKQGACVTQMHYAKKGIVTPEMEFIALREGLSPEFVREEVASGRAVIPANINHPESEPMIIGRNFHVKINANIGNSAVTSSIDEEVEKMTWAIRWGTDTMMDLSTGKDIHTTREWIIRNCPVPVGTVPIYQALEKVNGVAEDLTWDVYRDTLIEQAEQGVDYFTIHAGVRLRYIPLTVDRVTGIVSRGGAIMARWCLAHHQENFLYTHFEDICEIMKTYDIAFSLGDGLRPGSIADANDEAQFAELETLGELTEIAWKHDVQVMIEGPGHVPMDKIKENVDKQMEICKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKEDVREGVIAYKIAAHAADLAKGHPAAQKRDDALSKARFEFRWRDQFNLSLDPERAMAFHDETLPAEGAKTAHFCSMCGPKFCSMKISHDIRNQSEEVKKEMEKKAKEFISGGSQIYSS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: HCT1_CHLT2
Sequence: MALKDTAKKMTDLLESIQQNLLKAEKGNKAAAQRVRTESIKLEKTAKVYRKESIKAEKMGLMKKSKAAAKKAKAAAKKPVRATKTVAKKACTKRTCATKAKVKPTKKAAPKTKVKTAKKTRSTKK
What is the function of this protein?
Might have a role analogous to that of eukaryotic histone proteins.
What are the official names of this protein?
Histone H1-like protein Hc1, 18 kDa histone analog.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family. HCT subfamily.
Protein: M2DH_ASPOR
Sequence: MAPLKLNNKNLSQIAAAGETQVKVPTYKRGGDVKEGIVHVGVGGFHRAHLAVYVDQLMQKHGVTDYAICGVGLQPFDAAMRDALGSQDHLYTVIERSAKGSFAHVVGSINSYLFAPDNREAVIAKMAHPDTHIVSLTITESGYYYNENTHELQSEHPDIQFDLQPANEKSPRTTFGFLYAALARRYQQGLKPFTVMSCDNMQKNGSITRHMLESFARLRNPEIAKWIAEQGAFPNAMVDRITPQTSATDKTALADNFAIEDSWPVVTEPFMQWVIEDQFSDGRPPFEKVGAQVVKNVHDVEEFEKHKLRLLNGSHSAIGYPGQLAGFKYVHEVMENPLFSKFVWQMMQDEVKPLLPEIPGVNIDEYCKTLIERFSNPTIMDQLPRICLNASGKIPQFIMPSIAEAIWVTGPFRRLCFVAAAWFHYINGVDDSGKKFEVDDPMREELQAKARAGGTSPAELLSIKSLFGDDLRGDKRFLQEITKAMEDIARDGILKTLPKYID
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol 2-dehydrogenase, M2DH, MDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: DECO7_BPN15
Sequence: MAITEVFTHKQPLGNSDPAHTAYGPGELTASTPAMTPLMLDATSGKLTVWDGAHAGAATGILAVTADQNSAELAFYKSGSFRIEDVLWPSAVTDENIKRNAFAGTAISIV
What is the function of this protein?
Putative decoration protein.
What are the official names of this protein?
Putative decoration protein, Gene product 7, gp7.
What are the subcellular locations of this protein?
Virion.
Protein: RPOZ_SHISS
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ENGB_LEUCK
Sequence: MNVNNVEMVMSAVSAAQYPTDGKPEIALVGRSNVGKSSLTNTLIQRKNFARTSSQPGKTQTLNFYDVENQLYFVDVPGYGYAKVSKKQREAFGNMIEEYITSRKQLRGVISLVDARHDPSEDDVAMYEWLHYYNIPILVVATKSDKISKSKFNKYENNIKKQLGFDSSASDFLFFSSETKYGRDSVWEWITAHM
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: DTD_ALBFT
Sequence: MIAVLQRVSEARVLIEGQIVGEIGAGLLLLLCAERGDSETESDKLLSKVLKLRIFSDAAGKMNHSLQDMDGRGTAGGLLVVSQFTLAADVSGGNRPGFTLAAAPAQGRRLYDHFVAQARRAHPVVRTGQFGADMQVHLVNDGPVTIPLRMAPPAGVAPE
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.