PharMolix/UniProtQA huggingface dataset:
Protein: VATB_METVS
Sequence: MDAMQKTIEYTSVSRIAGPLMVIEGIEGIAYGEIVDITTPNGEKRTGQVLEAREDIAVVQVFEGTSELNTSETRVRFTGETAKIGVSKDMLGRIFNGAGKPLDGGPEIIAEKKVDINGYPLNPVSRNPPNAFVQTGISTIDGTNTLVRGQKIPIFSGSGLPHNMLAAQIARQAKVRGEGEQFAVVFAAMGITSEESNYFMDEFKKTGALEKAVVFINLADDPAIERIITPRIALTTAEYLAYEKGMHVLVILTDLTNYCEALREIAAARNEVPGRRGYPGYMYTDLASLYERAGRVKGKEGTVTQIPILTMPHDDITHPIPDLTGYITEGQIVLSRELNRKGIYPPVDILPSLSRLAGNGQGPGKTRDDHAKVISQAYAAYAEGRGLRDLVAVVGEEALTERDRAFLKFADAFEGRVVTQGVDEDRSIEETLDIIWELLTILPKSELKRVSDELIEKYLPKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: SIRC_SALTI
Sequence: MVLPSMNKSVEAISNNHLQQPNKFPLINGLADVRDYYVANCLLFKLNKGSLRIENEFGEFIEQSALCLFLLEKDQTITLSMSEIEGHIDFSSLEVSYDLMQKFYKVFYSTRNYNDRELSLKTKPKYFFHADLLPGMSDTFDSILHGVACPRVCSNVSIDDHDYSYFSLMYLISAFVRKPGGFDFLERAIKITTKEKVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIYLDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFIAIFKRHFKITPLSFMRTMNH
What is the function of this protein?
Positive regulator of the expression of the invasion-associated type III secretion system encoded within SPI-1 (pathogenicity island 1).
What are the official names of this protein?
Transcriptional regulator SirC.
Protein: NS1_I77AA
Sequence: MDPNTVSSFQVDCFLWHVRKQVADQELGDAPFLDRLRRDQKSLRGRGSTLGLNIETATCVGKQIVERILKEESDEALKMTMASAPASRYLTDMTIEEMSRDWFMLMPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTNEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWRSSNENGRPPLTPKQKRKMARTIRSEVRRNKMAD
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: SPX_STAES
Sequence: MVTLFTSPSCTSCRKAKAWLQEHDIPYTERNIFSEHLTIDEIKQILKMTEDGTDEIISTRSKTYQKLNVDIDSLPLQDLYSIIQDNPGLLRRPIILDDKRLQVGYNEDEIRRFLPRKVRTFQLQEAQRLVD
What is the function of this protein?
Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes.  Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP).  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
What are the official names of this protein?
Global transcriptional regulator Spx.
What is the protein family that this protein belongs to?
Belongs to the ArsC family. Spx subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALE_CORGL
Sequence: MKLLVTGGAGYVGSVAAAVLLEHGHDVTIIDNFSTGNREAVPADARLIEGDVNDVVEEVLSEGGFEGVVHFAARSLVGESVEKPNEYWHDNVVTALTLLDAMRAHGVNNLVFSSTAATYGEPDVVPITEDMPTQPTNAYGATKLSIDYAITSYAAAFGLAATSLRYFNVAGAYGNIGENREVETHLIPLVLQVATGHREKTFMFGDDWPTPDGTAVRDYIHILDLAKAHVLALESNEAGKHRIFNLGSGDGYSVKQVVEMCREVTGHPIPAEVAPRRAGDPATLIASSEKAKQELGWTPEHTDLRTIVEDAWAFTSALGDRSHAAKKKA
What is the function of this protein?
Involved in the metabolism of galactose.  Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (Probable).
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: METN1_BURCH
Sequence: MIELRNLSQRFPGPGGWVEALHNVNLTIPQGEVFGIIGRSGAGKSTLVRTINLLTRPTEGNVVVGGRDLTLLSAGALREARREIGMIFQHFNLLSSRTVFDNVALPLELAGASRADIEAAVLPLLDLVGLSAQKDRYPSQISGGQKQRVGIARALASQPKVLLSDEATSALDPETTRSILDLLKRINRELGLTIVLITHQMEVIKQVCDRVAVLDAGRVVEEGRVIDVFLQPHHEVTRALIGDVIAQELPPALKARVAERLKTGRGHLLRLAFTGSGVDQPILSETIRRYELDFNILHGQIDEIQGQAFGSLAVLAGGEPGKVGQALAFLREQGVVVEELSYVE
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DPES_ENTBW
Sequence: MRYFKEEVAGMKYGIYFAYWTKEWFADYKKYMDKVSALGFDVLEISCAALRDVYTTKEQLIELREYAKEKGLVLTAGYGPTKAENLCSEDPEAVRRAMTFFKDLLPKLQLMDIHILGGGLYSYWPVDFTINNDKQGDRARAVRNLRELSKTAEECDVVLGMEVLNRYEGYILNTCEEAIDFVDEIGSSHVKIMLDTFHMNIEETNMADAIRKAGDRLGHLHLGEQNRLVPGKGSLPWAEIGQALRDINYQGAAVMEPFVMQGGTIGSEIKVWRDMVPDLSEEALDRDAKGALEFCRHVFGI
What is the function of this protein?
Involved in the biosynthesis of D-psicose.  Catalyzes the reversible epimerization of D-fructose at the C3 position to yield D-psicose.  The enzyme is highly specific for D-psicose and shows very low activity with D-tagatose.
What are the official names of this protein?
D-psicose 3-epimerase, DPEase.
What is the protein family that this protein belongs to?
Belongs to the hyi family.
Protein: RL5_SHEPA
Sequence: MAKLHDKYKETVSPELVTKFGFTSVMQVPRIEKITLNMGVGEAVADKKVMEHALRDMTAIAGQKPVVTVARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSVKSFDGRGNYAMGVREQIIFPEIQYDKIDKIRGMDIVITTSAKNDEEGRALLEGFNFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MEND_STAES
Sequence: MNHSEALTEQVFSFASELYAYGVREVVISPGSRSTPLALAFEAHPNIKTWIHPDERSAAFFALGLIKGSEKPVAILCTSGTAAANYTPAIAESQISRLPLVVLTSDRPHELRSVGAPQAINQVNMFSNYVNFQFDLPIADGSEHTIDTINYQMQIASQYLYGPHRGPIHFNLPFREPLTPDLDRVDLLTSVTKTLPHYQKSISVDDIKDILQEKNGLIIVGDMQHQAVDQILTYSTIYDLPILADPLSQLRKEKHPNVITTYDLLYRAGLNLEVDYVIRVGKPVISKKLNQWLKKTDAYQIIVQNNDQIDVFPTPPHISYEISANDFFRSLMEEPLVERKKWLQQWQSLEQQARIEISDYLKHATDEAAYVGSLIQKLTKEDTLFVGNSMPIRDVDNLLFDSEASVYANRGANGIDGVVSTALGMAAHKNVILLIGDLSFYHDMNGLLMAKLNELHINIVLVNNNGGGIFSYLPQKRSATKYFERLFGTPTGLNFEYTALLYDFTFKRFDNLTDFKYAELSKMGSHMYEVITNRDENLHQHQNLYQKLSEIVNVTL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: FPG_GLUDA
Sequence: MPELPEVETVMRGMRLHLDGKTIARVAVRRADLRFPFPADLVARLEGATITGFARRAKYILIRLDTGDTLLLHLGMSGRVLLSLPGDAPVPDRHEHFFFETTDGTRCGLIDPRRFGAVDLMPTAEERAHRLLARLGPEPLGNQFSQHWLQEVLARRRTSIKAALLDQTVVAGLGNIYVSEALFRAGIHPARLACTLDAAEDARLVQAIRAVLREAIAAGGSSLRDYVQPDGELGYFQHAWRVYGRAGQGCPDCPGPPACHGVERLEQAGRSSFFCPLCQPPPGKVS
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PININ_CANLF
Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYILGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIGIVHSDAEKEQEEEEQKQEMEVKIEEETEVRESEKQQDSQPEEVMDVLEMLLHVAVKNVIAEQEVMETNQVESVEPSENETSKELEPEMEFEVEPDKECKSLSPVRENASALEMENEPEEKEERESEPQPEPVRHLQPLPQPEPEPELQPEPQPQLQPEPQLQPQLQLQLQPQPQSQSQPQPQLQLPLPLPLQPQPQVQAQSQPQAVLQPQPVSQPETLPLAVLQAPVQVIQEQGHLLPERKEFPVESVKLTEVTVEPVLIVHSDSKTKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGGSSSSGSSSSRSSSSSSSSTSGSSRRDSSSSTTSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR
What is the function of this protein?
Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'.  Capable of reversing CTBP1-mediated transcription repression.  Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  Participates in the regulation of alternative pre-mRNA splicing.  Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites.  Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets.  Involved in the establishment and maintenance of epithelia cell-cell adhesion (By similarity).
What are the official names of this protein?
Pinin.
What is the protein family that this protein belongs to?
Belongs to the pinin family.
What are the subcellular locations of this protein?
Nucleus speckle. Cell junction, desmosome. Note=Cell-cell contact area, predominantly desmosome of intercellular adherens junction. Not a nucleocytoplasmic shuttling protein (By similarity).
Protein: METAS_ECO81
Sequence: MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDGLIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLDPDVPYNYFPHNDPQNTPRASWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF1_VICFA
Sequence: LLGRCKVKSNRFHGPCLTDTHCSTVCRGEGYKGGDCHGLRRRCMCLC
What is the function of this protein?
Fabatins have antibacterial activity against Gram-positive and Gram-negative bacteria.  High activity against P. aeruginosa.  No activity against S. cerevisiae and C. albicans.
What are the official names of this protein?
Defensin-like protein 1, Fabatin-1.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: Y2036_STRA3
Sequence: MIKILIPTAKEMKVCQNIARPKLSAQTKIIIDYFSTLTVSDLEDIYRINTSAARCEAQRWQDFKSKQLTLNPAIKLFNGLMYRNIKRHNLSTSEAQFMENSVFITSALYGIIPAMTLISPHRLDFNTKIKINNNSLKVFWRENYDTFMQSDDIMVSLLSNEFETVFSPKERQKLIHLNFIEDRDGQLKTHSTISKKARGKCLTAMMENNCQTLEHLKQLRFDGFCYDNELSDSKQLTFVKKQT
What are the official names of this protein?
UPF0246 protein gbs2036.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: OPGC_SALPA
Sequence: MSSVPAPREYFLDSIRAWLMLLGIPFHISLIYSTHSWHVNSATPSWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPLKRWWKVRVERVGIPMLTAIPLLTLPQFILLQYVKEKTENWPTLSAYEKYNTLAWELISHLWFLLVLVILTTVSIGIFTWFQKRQETSKPRPAAISLARLSLIFFLLGMAYAAIRRIIFIVYPAILSDGMFNFIVMQTLFYVPFFILGALAFIHPDLKARFTTPSRGCTLGAAVAFIAYLLNQRYGSGDAWMYETESVITMVMGLWMVNVVFSLGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHISSNLIGFLCGLIFVMGIALILYEIHLRIPLLKFLFSGKPPVKQESRAAIG
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PANC_MYCS2
Sequence: MTISRTPKFSAGELNVYSAPADVAAVTRALRTAGRRIVLVPTMGALHEGHLTLVRAAKRTPGAVVVVSIFVNPLQFGPNEDLNAYPRTLEDDLTALRAEGVEIVFTPTGSDMYPDGTRTSVHPGPLGDDLEGSSRPGHFAGVLTVVLKLFSIVRPDRAYFGEKDYQQLTLLRQMVADLNVDVQIVGVPTVRESDGLALSSRNRYLDKDQREQAGALSAALLAGKYAAAGGAEAALDAARAVLDEVPALEVDYLQVRDPMLGPAPAEGQARLLVAARLGRTRLIDNIAIDVGASAGIDGHPRVGNDQNHELPWRN
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_ACIC5
Sequence: MLTDIALDAWGSDKAPEPEIKGAILACRHLPVRVHLVGQQDVLEPLLAQALRGARLPIEIVHASERIAMDEKAAQAVRTKRDSSMRVGLKLVREKKVAGFFTAGNTGAAMATAKMVLGALPGVDRPALALAVPTLTGPTILLDVGANTDCKAHNLEQFAVMGEMYARKVLKVDRPRVGILSVGEEEGKGNDLTREAFPLIKALPLNFIGNVEGRDIYNGHCDVIVCDGFVGNVALKTSEGILKLVREMLKISLKSTVTAQVGALLSRRAFDEFKRRLDPSEYGGTPLLGVRGVCIIGHGSSNDRAIMNGIRVAAEFATAGVNQQLEADFAAPADSHA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: LFR_ORYSJ
Sequence: MSHVRSAPAGKSGGGGGSTPAKRGRPFGSTTGSGAAAAAAAAAIGDAAAPAALVGPSLQVLTALSDQNNKRIVLALQSGLKSEILWALNALTVLSFKEKDDLRRDTTPLAKVPGLLDALLQVIDDWRDIAMPKDHTKPPRVRTLGVNTTLSGFGHENVEKVYSDTTTPSDDQTKTADSTVTKKRSAGFLFDEEGLFNVDDEGRTEKQQCAVAASNIIRNFSFMPENETVMVQHRHCLETVFQCLEDQNTEDDELITNMLETLVNLAPVLDLRIFSSSKPSFIKITEKRAVQAIMGMLASSIRVWHCAAAELIGRLIINPDNEPFLLPAIPQIYKRLVDLLSVPAVDAQAAAISALYNVAEVNMDFRLKLASERWAVDRLLKVVKTPHPVPEVCRKASMIVESLVSEPQNRMHLLVHENTFAEILTSEGKYSDTFARILYELTARPSNKVTAGQAIWGNIN
What is the function of this protein?
Plays critical roles in both embryo and endosperm development (PubMed:32808364).  Required for free nuclei division and cellularization in early endosperm development, by preventing premature cell death in the endosperm (PubMed:32808364).  Involved in the regulation of pattern formation and organ differentiation during embryogenesis, by regulating genes involved in the early stages of seed development (PubMed:32808364).
What are the official names of this protein?
Armadillo repeat-containing protein LFR, Protein LFR ortholog, OsLFR.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHF13_HUMAN
Sequence: MDSDSCAAAFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDAGFSDIASSVPLPVSDRCFSHLQPTLLQRAKPSNFLLDRKKTDKLKKKKKRKRRDSDAPGKEGYRGGLLKLEAADPYVETPTSPTLQDIPQAPSDPCSGWDSDTPSSGSCATVSPDQVKEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRTGSRKLFLD
What is the function of this protein?
Modulates chromatin structure.  Required for normal chromosome condensation during the early stages of mitosis.  Required for normal chromosome separation during mitosis.
What are the official names of this protein?
PHD finger protein 13, Survival time-associated PHD finger protein in ovarian cancer 1, SPOC1.
Protein: ZNT6_BOVIN
Sequence: MGTIHLFRKPQRSFFGKLLQEFRLVAADRRSWKILLFGAINLTCTGFLLMWCSSTNSIALTAYTYLTIFDLFSLITCLVSYWVMMRKPSPAYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSIRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFTDHHVIPMPPLKGTDDSNPVTSTPTKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYGLGLNHGHAPYSSVLNQGLGVPGIGATQGFRTGFTNIPSRYGTNNRIGQPRP
What is the function of this protein?
Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway.  As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis.
What are the official names of this protein?
Zinc transporter 6, ZnT-6, Solute carrier family 30 member 6.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Found in vesicles.
Protein: DAPF_CAUVC
Sequence: MSRTFLKMNGLGNDFVVIQTLTEAFDPTPEQIRAIAKRPGVDGKGGIGCDQVIAIDPPRAEGASAYVRFWNSDGEVAGACGNGTRCVAWLLMQSAGKDAVAFDTVAGRLSGVAAGDKLVTVDMGPPGLDWTQIPLAEEMNTERVELQVGPIDAPLVHTPVCVSMGNPHVVFFVDAPVTDDFARGTGSLVEHHPLFPEGVNVGFAHIASRDHIRLKVWERGAGLTQACGTGACAAQVAAVRRGLTDRKARVEFDTGSLTIEWRESDGHVIMTGPITMEYAGKLPELVAA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM10_CLAL4
Sequence: MYTHMEYLQRCFYKSTSWNEDNIYANVTATSQALLDFSIPSGAKLDVSTQATDHSASSMSLSNMHTINGSLAYLFSSTPLKNTMGTRDVSLQDAVAGFRIIEPFFSGTHTKTDSSDVNRASLLYGRMYFPGTALEAMLIKRISASAQLLVKCINNPHIRKGGTMIVYLQENTPRFSREYIYSTNEALFGFRCLYNFGKPTKISPALIPKFDNSVVSVGAEFWYAALGMSPGLSTAVRYSTRSTSTGKPLTMTLACNPILGHISSTYNVKTSVSSTVCSKYDFNWFSYASNLSIGFELYNFFKPSHVFKHYHADQRRNPSIHHDTLAPVADPYVLGTRPTNNSVSYAFPEKPRKRVVNSIQNLDDYYHINPSRLHRSPAYDVDDDVSGRSVMEAFQNSVNESNFSSVLKGSTSLSDRMVKLLWVGRYKDFLVSTGIKVNLNPFTNLPEINKIGVTFSYAC
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component MDM10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: G6PI_PSEMY
Sequence: MAYYQQPHDITRLPAWQALQQHRAEMAGFSMREAFAGDPRRFQRFSLDSCGLLLDYSKNLITEKSLELLIQLAEQADLHEAIAALYNGERVNASEGRAALHTALRSPIGRRLLVDGNDIIPEVHRVLNQVTELVSRIHSGLWRGYSEKPIKEVVNIGIGGSFLGPQLVSEALRPFTQRGVRCHYLANIDGSEFRELTARLDPETTLFIVSSKSFGTLETLKNTLAARDWYLAMGGPEEQLHRHFIAVTSNRKAAIEFGIGEENIFPMWDWVGGRYSLWSAIGLPIALAIGVSNFKELLAGAYAMDEHFTQAPLAENMPVLMALLGVWYTNFWGAQSHAILPYDHYLRNFTKHLQQLDMESNGKSVRQDGTPLDIATGPIIWGGVGCNGQHAYHQLLHQGRLLVPADFIVPVNSYNPLSDHHQWLFANCLSQAQALMQGKTREEAEVELRAKGLSEDEVQRLAPHKVIPGNRPSNILVMNRIAPFNLGALVALYEHKVFVQSAIWGINAFDQWGVELGKEMGKEVYQRLTGASGEPASDASTQGLIEHFRSQHRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_AERHH
Sequence: MSAEKKYVVALDQGTTSSRAIVFDQDANIVGTSQREFTQHYPKAGWVEHDPMEIWATQSSVFTEVLAKTGLRSEEIAAIGITNQRETTVVWEKATGKPIYNAIVWQCRRTAAICEELKARGLEEYVRENTGLVLDAYFSGTKVKWILDNVEGAREKAMNGELLFGTIDTWLVWKMTNGEVHVTDPTNASRTMLYNIRDLKWDQKMLDELGIPMSMLPQVKPSSEVYGYTTRGGGSRIPIAGIAGDQQSALFGQLCFEKGMAKNTYGTGCFMLMNTGTEPVRSNNGLLTTVAIGPKGEVNYALEGAVFMGGATIQWLRDELKIIHDARDTDYFASKVGDTNGVYLVPAFVGLGAPYWDPYARGTMVGLTRGANRNHIIRAALESIAYQSRDVLDAMQQDSGIKLAALKVDGGAVANDFLMQFQADMMHTPVVRPTRIETTAMGAAFLAGLAVGFWKSSEELEDKFSVDREFIPQMDRDDRAKRYNGWKKAVERSRRWAEEE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.