PharMolix/UniProtQA huggingface dataset:
Protein: U520_RAT
Sequence: MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALGDQPRDILCGAADEVLAVLKNEKLRDKERRREIDLLLGQTDDTRYHVLVNLGKKITDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKARLVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATGGHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD
What is the function of this protein?
Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome.  Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).  Involved in spliceosome assembly, activation and disassembly.  Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome.
What are the official names of this protein?
U5 small nuclear ribonucleoprotein 200 kDa helicase, BRR2 homolog, U5 snRNP-specific 200 kDa protein, U5-200KD.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAK_ALBFT
Sequence: MGRIIGIDLGTTNSCVAIMEGNTPKVIENSEGARTTPSIIAYQEDGEVLVGASAKRQAVTNPKNTLYAVKRLIGRKFTEKEVQKDINLMPYKIAAADNGDAWVEVRGNRMAPQQVSADVLRKMKKTAEDYLGETVTEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDKTEKGDRKIAVFDLGGGTFDVSIIEIADVDGEKQFEVLSTNGDTFLGGEDFDQRIIDFVIAEFKKEQGVDLGKDVLALQRLKEAAEKAKIELSSSAQTDINLPYVTADASGPKHLSIKLTRAKLESLVEELIERTIAPCRTAIKDAGVNVADINDVILVGGMTRMPKVQEKVKELFGREPRKDVNPDEAVAVGAAIQGQVLSGDRKDVLLLDVTPLSLGIETLGGVMTKMITKNTTIPTKFAQTFSTADDNQPAVTIKVFQGEREIAAGNKMLGEFNLEGIPPSARGTPQIEVSFDIDANGILHVGAKDKGTGKENKITIKANSGLTEAEIQQMVKDAELNAADDKRKLDLVQAKNQADASLHSVKKSLTEYGDKLEAGEKEKIEEAIKHLEEAIKGDDKAHIEEKSTALMTISQKLGEKMYADMQAKQAAEAGAGDPGAQAAAGAQNTSNQAADDNVVDAEVKEVKKG
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MYOI_DICDI
Sequence: MEDDDTLNGEYFQPVEDMITLPILTEESLLLNLKMRYKKKEIYTYTGSILVAVNPYEILPIYTADIVKSYFAKSRNLMLPHIFAVSDAAFTNMIEEGKNQSIIISGESGAGKTESTKLIIQYLAARTNRHSQVEQMIVESSPILEAFGNAKTIRNNNSSRFGKFIEIQFNREGHISGARIINYLLEKSRISHQASSERNYHIFYQLLAGASDELKEKLKLGEPEDYHYLSQSGCIRIENINDVEDFEHVKYAMNVLGLPEDKQFTIFSIVSAVLHIGNLKFEKSEKTQGAEGSEVSNKDTLKIIAQLLSVDPVKLETCLTIRHVLIRGQNFVIPLKVNEAEDTRDSLAKALYGNVFNWLVVFINSKIHKPQKNSTFIGVLDIFGFENFKKNSFEQFCINFANEKLQQHFNQHIFKLEQEEYEKEKINWSKIVYNDNQECLDLIEKRPLGILSLLDEESRFPQATDLTYLDKLHTNHEKHPYYEKPRRSKNTFVVKHYAGEVHYDTQGFLDKNKDTVSDDLSSLLQGSKSKFIIELFTPPREEGDDSDKGREKKKTTAGQTFKTQLQSLINILSSTQPHYVRCIKPNTTKEPAVYDRELIQAQLRYAGMMETIRIRKLGYPIRHTHKEFRDRYLILDYRARSTDHKQTCAGLINLLSGTGGLERDEWQLGNTKVFIRDHQYLKLEELRKLKLLKKVTLIQSVWRMYRCKKRYQQIRASAKILGAAMLSHSSRRDFQEQRQAVQRIKGFFKMLTYQKQFKIIQINLRIVQNNIRSFIARRHSRNAVLLKRDRNARMLEIQREKDEEERNRQEKEERDRQEKEDKEKETADRRQLQEEQKRREEELRAKREEEELKKLEEKKSQLKELNQIDELSSLERMLKEQQDKNINELDDFVNSLEAFSFEGGVDDSQPYSFNHKMYEMSPEALDKISITDLLQGLKQTVRSVTKFEVDESKFELPPGIENVLKRAPGIKRQASSFLPGQPIPDVYSSPQYPVDEADDDDSNNNYINSNNGDLPLPTSQSSDFSLPPPPSSSSMDFGLPPPPPSSSSGGTYSLPPMPVFDFGMIDPILGAPPPPPSTSDSTSPSATATGNNTPNSSSASASQSTNQVNPQPTVSVVELPQILNDEEISLYSFYDYANKNFNIEKLKQKDDIFSYQKSHIKSSLLVHSDAEQTKVAVEIFSKVLHYMNSNPLVSKKDPADFYSPVKFILTKGLAIESLRDEIYCQLIKQSTSNPIQDLNIRVWELIHFTCSTFPPTRKLIKYFAAYLKTTIQQSDVSKSVKDSAQASYFILQRFTLNGARKQVPSVTELESIKENRPIFVRITATDGSLKGLHIDSATTCQESSNDLSQRSRMRVNSKENGFTIIESFNGIERDIAPTDKLCDVLSKVENLQATLSSKIQVNFKFVFKKKLFFDNITNNVPTTSINVENEFYYHQLFNDLFNSNYCKDQDYQISIGSLKLQFESSDYTDEIRAWLPGNGRGKYFTTDIEKNRFDDFINKYKSHKGLSPEDAKKQMVQLLEKHPLANCSLVVCEHQSESLPYPKNFVLALNVNGINIYDPATSKMLESVKYSNQSQQNLKSDDKSVSIILENKSTLQAFTGDVQKLVSLIKEYSLYLRNNAKYARALKDYNVSDTSLLPFKRNDIITITFKDQENKWFMGQLNGKEGSFPVDHVEILLSDVPPPQPVHPVATLSPPMSPTIPNITNTPPPPPSISDSMSPPPQVGMLPPPPPPSVMGSTKPIEIPSLGIPPPPPSSSNSSVPNSPIGSPMMGIPPPPPTISVHSLSNSGNSTPPPPLPSLSTPPTLSTPPPISSPPNFRSSLRVSMLNTSNDGGDNSSDDPSKRLTVSPAIGTDSQLAQWASTRFRSFKRASTLNQQQATLKRKAPVDPNTAFYFNKDPIKESLIEMEAKLSKKAIKNFSEIMMWMGDYPIPKGQTASLVIQSIISRGIENHELRDEIYCQAYRQTNKNPKVESAKKGFELIYFLSITFSPSDSLLQPFMEQLMSRNIAIQSSSPQLASLIAVCIEKLESHPIPSYQQRKMGPSATEIQSFRSNLENGDISTCKIRFIDQSTKLAKINTYTTIREITDTVCRQYGISQQSIKMFGISAVNETAGISKVVSETDMIYDVLARWEQSEEKGEFYFQVRRRFFLDDVNKILDQEHLWTDDDICFELTYCQIRDEWMKGLYTNVNEKDSSIIAAILIQLLYPNQSKLVLTKEVVRQVLPDQILNSQNIKVWISMIESQIFELVSQTPEYLKLMFINLIGSKSPLFGCTLFNIQQKENPPKAWLAINKKGVSIFDPHTKESKNFWTFQSISNVAFTDDTFCIMTGNLMKPIKQTFTTDEHSSIASVYQFYSSQ
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Involved in the early steps of phagocytosis and adhesion.
What are the official names of this protein?
Myosin-I heavy chain, Class VII unconventional myosin, DdMVII, DdM7.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Enriched in filopodia.
Protein: SPED_SALCH
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDQTKHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDVNGMKHFIDHEINSIQNFMSEDMKSLYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTETERQEITAALWKEMREIYYGRNISAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: SELA_SHIBS
Sequence: MTTETRSLYSQLPAIDRLLHDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRDSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM25_YEAST
Sequence: MHRTAIFLTYRSCMRNFSTLSKTLTVSSGKVIRNGPFRRVIREKNQITKAPSVKAFKENSNSGIIKVHDPIATTILNEPTVIIERQIEFMNVFLGFEQANRYAIMDVNGNKIASMMERDFSITKAIMRQFYRLHRPFLVDVFDNWGNVIMTIKRPFSFINSHIKTIIPPSAYVDNGSDSTHYHDGKEGTTVGETIQNWHLWRRRYELFQKDGVEGSTFDQFGKIDAPFLSFDFPVTDADGKIMASVDRNWVGLGREMFTDTGVYVVRFDSQRCFDNIYPTEMLSSQVLTLDQRAVLLANAVSIDFDYFSRHSRQTGGFLSFGGGYDE
What are the official names of this protein?
Altered inheritance rate of mitochondria protein 25.
What is the protein family that this protein belongs to?
Belongs to the phospholipid scramblase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RIMM_LIGS1
Sequence: MNYYEVGKIVNTHGIKGELKIISKTDFPEDRFKPGNILYIRDNGKINSYEIKSHRTHKQFEMITFKGLENINLVENLKGKILEISEEQQENLSDGNYYHHQIIGLDVFSEDNNYIGVIKEIMSPGANDVWVVKRKGSSDLLLPAIKDVIKKIDLEQNKVIIELLDGLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMI2_ARATH
Sequence: MGERNLDGTVSVKATINKYGQKATRSVIKSSVAEDLHKSGRELGIYRESRRVAESAKAKAEVELCKAKKIVKELTLRIEESNRRLKSRRIDIEAVMNESRIDGNGGYVRIMRELEDMKQELSKLKLDVVYVSREKVVAEKEVMELESRMEENLKLLESLKLEVDVANEEHVLVEVAKIEALKECKEVEEQREKERKEVSESLHKRKKRIREMIREIERSKNFENELAETLLDIEMLETQLKLVKEMERKVQRNESMSRSKNRAFERGKDNLSVLKEVTEATEAKKAELASINAELFCLVNTMDTLRKEFDHAKKETAWLDKMIQKDDVMLERLNTKLLIAKDQLEAVSKAEERISYLADNLTTSFEKLKSDREAAKKEELKLREEARIINNEIQKTETGFDGKEKELLSKLDELEKAKHAESLALEKLETMVEKTMETREMESRRNSTITISRFEYEYLSGKACHAEETAEKKVEAAMAWVEALKASTKAIMIKTESLKRVSGKTMLEEERESFRMQRSLSIKRLVQDEIQKFKGNSEDNGLINSPKPVRKSVRLSGKFAPVQGGKSRRYSSGNRATPTFFVIKKKKKVPNMVKFFSRKRRNSSLEQ
What is the function of this protein?
Required for the chloroplast avoidance response under high intensity blue light.  This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells.  Acts in association with WEB1 to maintain the velocity of chloroplast photorelocation movement via cp-actin filaments regulation.
What are the official names of this protein?
Protein PLASTID MOVEMENT IMPAIRED 2, Protein WEAK CHLOROPLAST MOVEMENT UNDER BLUE LIGHT 2, Protein WEB2.
What is the protein family that this protein belongs to?
Belongs to the WEB family.
Protein: ORC4_CRIGR
Sequence: MSNRKTKGNSAVHPECLSQVQRILRERFCHQSPHSNLFGVQVQYKHLIELLKRTAINGESNSVLIVGPRGSGKTMLINHALKELMEIREVSENVLQVHLNGLMQINDKIALTEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGNRANSCPVIFILDEFDLFAHQKNQTLLYNLFDISQSAQTPVAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFDFPQYMKIFKEQLSLPEEFPNKVFAERWNENTQSLSEDSTVREVLQKLFNVNKSLRSLHMLLMLALNRVTVSHPFMTSADLMEAQHLCSLDSKASIIHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSVNSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent.  The specific DNA sequences that define origins of replication have not been identified yet.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.  Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 (By similarity).
What are the official names of this protein?
Origin recognition complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the ORC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFP_LEPBA
Sequence: MNLGITEVKKGMILKIDNELYSVVKTEFVNPGKGSAFIRTKLKNIVRDSSIERTFKAAEKLESVDLERRKMQYCYADGDQIIFMDVNDYEQIPVSKDYVEDILPFMKEETPVEVAFYNDKPIGVTPPNFAILEVTYAEDGLKGDTTGLALKRVTVETGGEVQVPIFIKQGDTVKIDLRDLSYVERVNK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D13_SWPVK
Sequence: MNNTVINSIIGNDDIVKRHNVFGVDVQNPTLYMPQYITINGITSTDSNCDQHVVSTFEIRDQYITALSHVMLSIELPEVKGVGRFGYVPYVGYLCIQHVSISSYDDILWESSGEDLYNSCLDNDTALTNSGYSHELNTISTGLTPNDTIKESTTVYVYIKTPFDVEKTFSSLKLADTKIVITVTFNPVSDIIIRDITFNYDNFVKDFVYVTELSCIGYMVKNIQIKPSYIERPRRVFGQLNQSTAVISDVHSVSSLSVYIKPYYGNADNKFISYPGYSQSEKDYICVFVERLLDDLVTVCDTSPKWFPETAELVEVPNSGIVTIQDVDIFVRIDNVPCNMKVYFHTNILVFGTRKNSVTYNLSKKFTTITGTYSESTNRIMFSHVSHSINITDVSIPVSVWTCQRNIYNGDNRSESSKNKDLFINDPFIKGIDFKNKTDIISRLEVRFGNDVLYSETSPISKVYNDLLSNHKCGMRTLRFNFTPPTFFKPTTIVANPSRGKDKLSVRVVFTSLDPNNPIYYISKQLVLVCKDLYKVTNDDGINVTKIIGEL
What is the function of this protein?
Scaffold protein which forms a transitory spherical honeycomb lattice providing curvature and rigidity to the convex membrane of crescent and immature virions (IV).  This association occurs concomitantly with viral membrane formation.  Targeted by the drug rifampicin, which prevents the formation of this lattice, and hence virus morphogenesis.  In the presence of rifampicin, irregularly shaped membranes that lack the honeycomb layer accumulate around areas of electron-dense viroplasm.  This layer is lost from virions during maturation from IV to mature virion (MV), through the proteolysis of A17 N-terminus (By similarity).
What are the official names of this protein?
Scaffold protein D13 ortholog, 62 kDa protein, Rifampicin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the poxviridae protein D13 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Associates transitorily with crescent and IV membranes.
Protein: ATOE_ECOLI
Sequence: MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPISMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVTFFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPLLAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPKLLMEEADFQKQLPKDAPPSERLEESRILTLIIGALGIAYLAMYFSEHGFNITINTVNLMFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFINVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVIPAAQALGADLGKSVMAIAYGEQWMNMAQPFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF
What is the function of this protein?
May be responsible for the uptake of short-chain fatty acids.
What are the official names of this protein?
Putative short-chain fatty acid transporter.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBB_THEVL
Sequence: GLPWYRVHTVLINDPGRLIAAHLMHTALVAGWAGSMALYELATFDPSDPVLNPMWRQGMFVLPFMARLGVTGSWSGWSITGETGIDPGFWSFEGVALAHIVLSGLLFLAACWHWVYWDLELFRDPRTGEPALDLPKMFGIHLFLAGLLCFGFGAFHLTGLFGPGMWVSDPYGLTGSVQPVAPEWGPDGFNPYNPGGVVAHHIAAGIVGIIAGLFHILVRPPQRLYKALRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDSSYFQQEINRRVQASLASGATLEEAWSAIPEKLAFYDYIGNNPAKGGLFRTGPMNKGDGIAQAWKGHAVFRNKEGEELFVRRMPAFFESFPVILTDKNGVVKADIPFRRAESKYSFEQQGVTVSFYGGELNGQTFTDPPTVKSYARKAIFGEIFEFDTETLNSDGIFRTSPRGWFTFAHAVFALLFFFGHIWHGARTLFRDVFSGIDPELSPEQVEWGFYQKVGDVTTRK
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RL16_CHLP8
Sequence: MLMPKRVQYRKTQRGRMKGNAQRGTAVTFGSFGLKALEPAWITSRQIEAARVAMNRYMKRDGKIWIRIFPDKPVTKKPAETRMGSGKGNPEFWVAVVKPGRIMFEAAGVPREIAQEAFRLAAKKLPIKTRFIVRPDYEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: KAPR_DEBHA
Sequence: MTDNQYATEELNQLQKELVAKNPIDVLQFCANYFNSKLELQRSQLWQQQNKAKAAGINLFPSIDNVFNSDGGAIMTTNKRQPSFKSPFGDNDPTSIDHHHDDDPKEAPGASKQQNKAELFKGGFGVGKSTPSKPLQELDPNDPSHSASQDTDAAPPVPKSKIPVAFNANRRTSVSAEAMNPNKFKSDSWKPPINDLTAAQKVELSKTLGSNFLFRQLDVSSKKTVIEALGKKEFKNGDEIIKQGDEGDYFYIIEKGTVDFYVNGNQVNSSGEGSSFGELALMYNSPRAATAVAASDTGVTCWALDRQTFRRILLERTFNRRLMYEDFLKDVKVLSSLSSQERSKLADALSTEIYHKGDKIVKEGEQGENFYFIESGSCQVSKDGKGVLTKLSKGDYFGEVALLNDLPRQATVEALDTVIVATLGKSGFSRLLGPAVDILKSQDPTANQGSSN
What are the official names of this protein?
cAMP-dependent protein kinase regulatory subunit, PKA regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
Protein: CENPQ_RAT
Sequence: MSGKANTSKKKSQRVKRNVKQRADKEDEELDSPENKVGNRAKRNRSHAGHLSSKEQTKCVHLKRVKISSNKRTAWQPLPKNTEEYLQSMMDSAILGILNKNIKRKEQIQYHLDQLKKRFLQQCATLKVPPGKLNYLRDMSKLLKVEREQERANEESLASLQEEIDKIVETTESMTENIESLKTKIEILTNEVEKEEEEMKEVFHIDSNKVLALPELSQKSLKAPILQKEILTLIPNQNALLKDLDVLQNSAPGKNMAAFIQEAYMKLNGS
What is the function of this protein?
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.  Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores.
What are the official names of this protein?
Centromere protein Q, CENP-Q.
What is the protein family that this protein belongs to?
Belongs to the CENP-Q/OKP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Protein: DAPB_ECOK1
Sequence: MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECR_RAT
Sequence: MEPLLPTPPLLLLLLLLLSSSFVLPAPPRTPRHSDGTFTSELSRLQDSARLQRLLQGLVGKRSEEDTENIPENSVARPKPLEDQLCLLWSNTQALQDWLLPRLSLDGSLSLWLPPGPRPAVDHSEWTETTRQPR
What is the function of this protein?
Hormone involved in different processes, such as regulation of the pH of the duodenal content, food intake and water homeostasis (PubMed:7958688, PubMed:8568688, PubMed:3047699, PubMed:9655680, PubMed:19805236).  Exerts its biological effects by binding to secretin receptor (SCTR), a G-protein coupled receptor expressed in the basolateral domain of several cells (PubMed:9506976, PubMed:12403838).  Acts as a key gastrointestinal hormone by regulating the pH of the duodenal content (PubMed:7958688, PubMed:8568688, PubMed:3047699, PubMed:9655680).  Secreted by S cells of the duodenum in the crypts of Lieberkuehn and regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate (NaHCO(3)) from the ductal cells of the pancreas (PubMed:7958688, PubMed:8568688, PubMed:3047699, PubMed:9655680).  Production of bicarbonate is essential to neutralize the pH and ensure no damage is done to the small intestine by the gastric acid (By similarity).  In addition to regulating the pH of the duodenal content, plays a central role in diet induced thermogenesis: acts as a non-sympathetic brown fat (BAT) activator mediating prandial thermogenesis, which consequentially induces satiation (By similarity).  Mechanistically, secretin released by the gut after a meal binds to secretin receptor (SCTR) in brown adipocytes, activating brown fat thermogenesis by stimulating lipolysis, which is sensed in the brain and promotes satiation (By similarity).  Also able to stimulate lipolysis in white adipocytes (By similarity).  Also plays an important role in cellular osmoregulation: released into the systemic circulation in response to hyperosmolality and acts at different levels in the hypothalamus, pituitary and kidney to regulate water homeostasis (PubMed:19805236).  Also plays a role in the central nervous system, possibly by acting as a neuropeptide hormone: required for hippocampal synaptic function and neural progenitor cells maintenance (By similarity).
What are the official names of this protein?
Secretin.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: YRAO_BACSU
Sequence: MLTILGFSMVTVFTILIMTKKVSPIVALTITPIVFALIGGFGKGIGDMILEGIQTVASSAALLLFAILFFGILIDAGLFDPLIEKILSIVKGDPVKIAIGSAVLAMLIALDGDGTTTYMITVSAMLPLYKRIGMNPMVMATLAMLSLSIVSGMTPWGGPATRAISVLGLDPSDFFVPLLPTMLGGIACVIFLAFLMGRKERNRIGIVQLEPRHITKDSSQSYMAATLESEQLKRPRLIYLNLFLVISIMVFIVLGTKHPSVLFLIGFVLALTINYPNVKMQKERIAEHSGNAITVVLLVFSAGVFAGILSGTKMVDAIAGSLISIIPSSMGGFFPVIVALTSIPFTFVLSNDAYYFGMVPIFAEAASAYGIEPVEIARASIMGQPVHLMSPLVASTVLLVSMLKMDLGSFQRFAVKWAVITSLVITLLAIITGAITIL
What is the function of this protein?
Transports the free citrate anion.
What are the official names of this protein?
Uncharacterized transporter YraO.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LDH_PRIMG
Sequence: MKTQFTPKTRKVAVIGTGFVGSSYAFSMVNQGIANELVLIDMNKEKAEGEARDINHGMPFATPMKIWAGDYKDCADADLAVITAGANQAPGETRLDLVEKNVKIFECIVKDIMNSGFDGIILVATNPVDILAHVTQKVSGLPNGRVIGSGTILDTARFRYLLSDYFEVDSRNVHAYIMGEHGDTEFPVWSHAQIGGVKLEHFINTAAIEKEPDMQHLFEQTRDAAYHIINRKGATYYGIAMGLVRITKAILDDENSILTVSALLEGQYGISDVYIGVPAIINKNGVRQIIELNLTPHEQQQLEHSASILKQTRDRAFV
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.