PharMolix/UniProtQA huggingface dataset:
Protein: PA2A_CERCE
Sequence: NLYQFGKMIFKMTGKSPIFSYGDYGCYCGWGGKGTPVDATDRCCFVHDCCYGRVNSCNPKRSTYSYSFQNGGIVCDDQNLCKRAVCECDRVAAICFGENVNTYDKKYKDYPTSQCTETEQ
What is the function of this protein?
This non-toxic acidic phospholipase A2 hydrolyzes monolayers of different short chain phospholipids (PubMed:2402760).  It exhibits anticoagulant effects upon human plasma in vitro (PubMed:30239061).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2402760).
What are the official names of this protein?
Acidic phospholipase A2 Cc1-PLA2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CLC2L_MOUSE
Sequence: MEPAREPPARARPPPPAARPAPAAPRPRSPAEAEARGPEGLLRRSGSGYEGSTSWKAALEDTTTRLLLGAIAVLLFAILVVMSILASKGCIKCETPCPEDWLLYGRKCYYFSEEPRDWNTGRQYCHTHEAALAVIQSQKELEFMFKFTRREPWIGLRRVGDDFHWVNGDPFDPDTFTISGMGECVFVEPTRLVSTECLTTRPWVCSKMAYT
What are the official names of this protein?
C-type lectin domain family 2 member L.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: COBB_BRUSU
Sequence: MKGFMIAAPASGSGKTTVTLGLLRALKRRGEVLAPVKAGPDYIDPAYHRAASGVDCFNLDPWAMRPGLISALSSRMTESGARVLVAEGMMGLFDGAIDGKGSSADLARLLDLPVVLVVDCARQSHSIAALVWGFSQFRKDVLIEGVILNRVGSPRHEAMLRGALAPLGVPVLGALPRDPALSLPERHLGLVQADEHAGLESFLEQAADVMEAHIDMDALQTIWLRPKRYDAMANVARLKPLGNRIAVARDDAFAFAYMHLFEGWRRRGAEISFFSPLADEAPKADADAIYLPGGYPELHAQRLAGASRFRTAIGDAAARGVTVYGECGGYMVLGKTLEDAAGVHHPMLGLLPLETSFARRKLHLGYRLLEPLGGLPWDMPLKAHEFHYASIVREEKADRLFRVRDASGENLGEAGLRVGSVSGSFMHVIDFSGEAA
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Hydrogenobyrinate a,c-diamide synthase, Hydrogenobyrinic acid a,c-diamide synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: HTPX_SYNFM
Sequence: MGSRFRTTVLLAALTALIIWIGGAVGGSHGMMIAFVLALVMNVGSYWFSDKIVLAMYRAQPLSEADAPQIYRIVRELSASANLPMPRVYLIPESAPNAFATGRNPENAVIAVTEGLWRILTPDEIRGVLAHELAHVKNRDILVSSIAATLAGVVMILARMAQWGALFGGGRSSSDEDSGGGMLGLVVTAILAPIAAMLIQLAISRSREYLADETGAAFSHNPESLARALEKLAMASHQNPMEDASPSTAHLFIVNPLSGRSLANLFSTHPPIEERIRRLRSM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAA_METPP
Sequence: MHDKILILDFGSQVTQLIARRVREAHVYCEIHPNDVSDEFIREFAPKGIILSGSHASTYEDHDLRAPQAVWELGVPVLGICYGMFTMVVQQGGEVEASAHREFGYAEVRAHGHTRLLQGIEDFSTPEGHGMLKVWMSHGDKVTKLPPGFKLMASTPSCPIAGMADESRGYYAVQFHPEVTHTVQGRALLERFVLEIAKAQPDWVMKDHVAEAVAAIRAQVGDEEVILGLSGGVDSSVAAALIHRAIGDRLTCVFVDHGLLRLNEGDMVMEMFAGKLHAKVVRVDAAELFMNELAGVADPEAKRKIIGRLFVDVFKAEAAKLKASGAGHRGATFLAQGTIYPDVIESGGAKTKKATTIKSHHNVGGLPEQLGLKLLEPLRDLFKDEVRELGVALGLPHDMVYRHPFPGPGLGVRILGEVKKDYADLLRRADAIFIEELRNTVDPASGKTWYELTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVQTSDFMTADWAELPYALLKRTSGRIINEVRGINRVTYDVSSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: VATB_STRPC
Sequence: MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKGQVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGGPELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHNELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLANDPAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYPGYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQELYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLGESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDDMLDRYLPKADTTMTKVFVAND
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: HEM3_EHRCR
Sequence: MNIRIGTRGSILAIAQTLEIKNLLNRYFPEISVQIVKIKTSGDINNQVPLSAIGGKSLFIKEIEEALLMGKVDLAVHSVKDIPAFYCEGLIIPCVLKRNSPYDVFISSKHKDIKSLPLNATIGTSSVRRKVQLNYLRPDLQVVPVRGNIDTRILKANVGEFDGIVLAEAGLIRINRCDVIKEILSPKIMLSAVGQGAIGIQCRVDDHSIINKIKVLNCHQSYVCVMAERSFLKTINGSCDTPLAALAQYVNNDTIHMSCMLANEKNMVFASCCFNECDAEKSGINMGKKLMDELSQYY
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: HISN_STRCO
Sequence: MPDYLDDLRLAHVLADAADAATMDRFKALDLKVETKPDMTPVSEADKAAEELIRGHLSRARPRDSVHGEEFGVAGTGPRRWVIDPIDGTKNYVRGVPVWATLIALMEAKEGGYQPVVGLVSAPALGRRWWAVEDHGAFTGRSLTSAHRLHVSQVSTLSDASFAYSSLSGWEEQGRLDGFLDLTREVWRTRAYGDFWPYMMVAEGSVDLCAEPELSLWDMAANAIIVTEAGGTFTGLDGRPGPHSGNAAASNGRLHDELLGYLNQRY
What is the function of this protein?
Catalyzes the dephosphorylation of histidinol-phosphate to histidinol, the direct precursor of histidine.
What are the official names of this protein?
Histidinol-phosphatase, HolPase, Histidinol-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: LSH4_ARATH
Sequence: MDHIIGFMGTTNMSHNTNLMIAAAATTTTTSSSSSSSSGGSGTNQLSRYENQKRRDWNTFGQYLRNHRPPLSLSRCSGAHVLEFLRYLDQFGKTKVHTHLCPFFGHPNPPAPCACPLRQAWGSLDALIGRLRAAFEENGGSPETNPFGARAVRLYLREVRDSQAKARGISYEKKKRKRPPPPLPPAQPAISSSPN
What is the function of this protein?
Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity).  May suppress organ differentiation in the boundary region.
What are the official names of this protein?
Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 4, Protein ORGAN BOUNDARY 4.
What is the protein family that this protein belongs to?
Belongs to the plant homeotic and developmental regulators ALOG protein family.
Protein: DAPE_NEIG2
Sequence: MTETQSLELAKALISRPSVTPDDRDCQKLLAERLHKIGFAAEELHFGDTKNIWLRRGTKAPVVCFAGHTDVVPTGPVEKWDSPPFEPTERDGRLYGRGAADMKTSIACFVTACERFVAEHPDHQGSIALLITSDEEGDALDGTTKVVDVLKARGELIDYCIVGEPTAVDKLGDMIKNGRRGSLSGNLTVKGKQGHIAYPHLAVNPVHTFAPALLELTQEVWDEGNEYFPPTSFQISNINGGTGATNVIPGELNVKFNFRFSTESTETGLKQRVHAILDKHGVQYDLQWSCSGQPFLTHAGKLTDVARTAIAETCGVEAELSTTGGTSDGRFIKAIAKELIELGPSNATIHQINENVRLDDIPKLSAVYERILARLLAEKAV
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RL35_PROA2
Sequence: MPKMKSHRGACKRFKKTASGKVKRERMYGSHNLEKKNRKRTRRLHQSTLVDSTQEKQIKRMILA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MET25_MOUSE
Sequence: MAAACPLPRTPDLPTLHDKLQGLLSFLRGALAISSAHTVDFYTKSVWQELVDLPPESVLAALRESAVEAEPREAETGSGFTELPKIFCETSQKLLSVEAFARTAKHYSVQNLGLCTPSEQLLTALQGNKRQRVDENVKAIEFMNTKKSHEVQAMSELICSIADYCGLKQIIDVGSGKGYLSSFLSLKYGLNVYGIDSSNTNTHGAKERNRKLKKHWSLYHPHSRADANGWASERPRELKVPKGVECKGDAESVQRSRLGNPDLSATDGLPDFSGSAISVIRKQQKNVLAQPAEEENLYFEDAFSLIDFLPVDAIEPTSSQVQNTEKSGLRKERRNTASKARDSSIYSPLTSFITADSQLHDIIEDLEDCLMVGLHTCGDLAPSTLRIFTSKAEVKAVCSVGCCYHLLSEEFENQHKDRCANENWGFPMCHYLKEERWCCGRNARMSACLALQRVAVGQGLPTESLFYRAVLQNIIKDYYGISKCEQHVGKIYSKCSSFLEYVRMSLKKLGLDESKVSEEIIMDYYENYKPRMNELEAFNMLKVVLAPCIETLILLDRLCYLKEQDGVAWSALVKLFDPVQSPRCYAVIALKKQCDLG
What is the function of this protein?
Probable methyltransferase.
What are the official names of this protein?
Probable methyltransferase-like protein 25.
Protein: TAGX_STAAR
Sequence: MRLTIIIPTCNNEATIRQLLISIESKEHYRILCIDGGSTDQTIPMIERLQRELKHISLIQLQNASIATCINKGLMEIKMTDPHDSDAFMVINPTSIVLPGKLDRLTAAFKNNDNIDMVIGQRAYNYHGEWKLKSADEFIKDNRIVTLTEQPDLLSMMSFDGKLFSAKFAELQCDVTLANTYNHEILVKAMQKATDIHLVSQMIVGDNDIDTHATSNNEDFKRYITEIMKIRQRVMEMLLLPEQRLLYSDMVDRILFNNSLKYYMNEHPAVTHTTIQLVKDYIMSMQHSDYVSQNMFDIINTVEFNGENWDREIYELWRQTLIQVGINRPTYKRFLIQLKGRKFAHRTKSMLKR
What are the official names of this protein?
Putative glycosyltransferase TagX, Teichoic acid biosynthesis protein X.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: CAF1P_ORYSJ
Sequence: MATSHLTSRSLLVQAQYPISRLPSNLRLSLSHHKQPAAVAKRRRAPAPSHPAFSSVIRGRPKKVPIPENGEPAAGVRVTERGLAYHLDGAPFEFQYSYTETPRARPVALREAPFLPFGPEVTPRPWTGRKPLPKSRKELPEFDSFMLPPPGKKGVKPVQSPGPFLAGTEPRYQAASREEVLGEPLTKEEVDELVKATLKTKRQLNIGRDGLTHNMLENIHSHWKRKRVCKIKCKGVCTVDMDNVCQQLEEKVGGKVIHHQGGVIFLFRGRNYNYRTRPIYPLMLWKPAAPVYPRLVKKIPDGLTPDEAEDMRKRGRQLPPICKLGKNGVYLNLVKQVREAFEACDLVRVDCSGLNKSDCRKIGAKLKDLVPCTLLSFEFEHILMWRGNDWKSSLPPLEENDFKVASDQILNSKEAGSGSALTPIELVNNATSLKKCNLIEGAEKLEDSMKSSFENGMILGSACGNPGVCNSEGIDGTESSADAPIEFSPSNSARDLDPSQTSTLYCQSSLLDKSENGELIEMYPDRCGNSEQSPDVPEALTCLMGSSDEIHELETMRRNCKHLNGSDGVNSDSIVPSYMEGILLLFKQAIDSGMALVLNENEFADANYVYQKSVAFTKTAPRYLVLRHTPRKSHGTQKTEPAKNVRINKHLEEHKVSDHVKKKEIVMGGSRMQRNDHAREFLSDVVPQGTLRVDELAKLLA
What is the function of this protein?
Required for the splicing of group IIB introns in chloroplasts.  Forms splicing particles with CRS2.  Interacts with RNA and confers intron specificity of the splicing particles (By similarity).
What are the official names of this protein?
CRS2-associated factor 1, chloroplastic, Chloroplastic group IIA intron splicing facilitator CRS2-associated factor 1.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: C508C_DICDI
Sequence: MELLNSLLLLFLIYLIHSFYIKNKRIHKNEAKGPIGFPLIGNMIQIGKTKPHIELMKLEKIYNQRILKIWLGDYYSVFLSDIDLIKDIFINKFENFSSRPKSPLTRLGTNDFRGINGSSGETWFKNKNIIVNAMKRANTKTIYTLLDNQVNDLIKEISKFESQNKSFNPKYYFRKFVLSTMFKYIFNEDVPYDENLENGKLSELTMEMENIFKTLKVGKLANSIEILETPYYYYLQKTDKVFKNIKKLIIEKYKNHNLSINPEKPRDLLDILINEYGTTDDDVLNITQVTLDMFMAGTDTTANTLEWIIIKLCNSPIHQEIAYNELKKVVSSKVIIDDSIKREITLSDRPNTPYIQAIIKETMRMHPVVVFGLPRYCENDIFIGDENYFIPKGCKVFINFHSIGYNEKYFKDPYKFEPNRFLENSNNSMDSFFPFGLGNRVCLGRQLANDQLYLVIANLILKYKLKTIDENKINEDGIFGLTVSPNKYKINLESR
What are the official names of this protein?
Probable cytochrome P450 508C1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TBX1_DANRE
Sequence: MISAISSPWLTQLSHFCDVAAFTTSSLSSLNTPGSYHLSPSPGDPYSHHESQFEPCPAAQHAYNYSGSNSAQAPAQGDSGTSNCSSSSSSSTPNKTLVKKNPKVANINVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKIFGMDPMADYMLLMDFLPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENYKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGSLQIMSAFARTRNPMSSPPQQNGTEKEDSRREYDRDPSGNPLHSDPTHQLMSRVLSPALPVLGGLHAVPLTAGPRSPPHELRLDGHPQPPDTLHHHPYKYPATYEHYLGAKTRPSPYPSPSIRGHGYHPHMNPTTANMYSATSAPTNYDYGPR
What is the function of this protein?
Probable transcriptional regulator involved in developmental processes (By similarity).  Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence (By similarity).  Is required for normal development of the pharyngeal arch arteries (By similarity).  Acts cell autonomously in the pharyngeal mesendoderm and influences the development of neural crest-derived cartilages secondarily.
What are the official names of this protein?
T-box transcription factor TBX1, T-box protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYC1_SYNY3
Sequence: MRMFRITACVPSQTRIRTQRELQNTYFTKLVPYDNSFREQQRIMKMGGKIVKVELATGRPGTNAGLA
What is the function of this protein?
Rod linker protein, associated with allophycocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity).
What are the official names of this protein?
Phycobilisome 7.8 kDa linker polypeptide, allophycocyanin-associated, core, LC 7.8.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=This protein occurs in the rod, it is associated with allophycocyanin.
Protein: NRDIL_STRP6
Sequence: MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKHETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQRCLGIIGSGNKNFNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQLIMEASSRHSSNDTQTLPNS
What are the official names of this protein?
Putative NrdI-like protein.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: T106A_RAT
Sequence: MGKAFSQLTSQKDEDKSILPDNPAMASKAANYFSTGNRKPSHSCVPCEKAASTSFVTCPTCQGNGEIPQELEKQLVALIPYGDQRLKPRRTKLSVFLAVTICLLIFSLTIFFLYPRNIVVHPVGLNSSTVAFDETHVQLNMTNVLNITNSNFYPVTVTQLTAEVLHQTSVVGQVTSSLRLHIGPLASKQMPYEVASRILDENTYKICTWPKIRVHHILVNIQGALTCSYLTHPQQLPFESFEYVDCRENMSMPHLELPRPA
What is the function of this protein?
Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway.  Upon activation, up-regulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide (By similarity).  May play a role in inhibition of proliferation and migration (By similarity).
What are the official names of this protein?
Transmembrane protein 106A.
What is the protein family that this protein belongs to?
Belongs to the TMEM106 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CB2E_SOLLC
Sequence: MAASTMALSSSTFAGKTVKLAPSSSEITGNGRITMRKTAAKPKPASSGSPWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLVHAQSILAIWACQVVLMGAVEGYRIAGGPLGEVVDPLYPGGSFDPLGLAEDPEAFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLENLADHIADPVNNNAWAFATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein 3A, chloroplastic, LHCII type I CAB-3A, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: FOXS1_MOUSE
Sequence: MQKQPSPESLAPSAEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFQHGSFLRRRRRFTKRTGAQGTKGPVKIDHRPHRATSPDPGAPKTTTGRLCPFPQEVPNPKGLSFEGLMGSLPANMSSTTSDVRPQLPTGPKEMCSAKSGGPRELSEATSPSPCPAFGFSSAFSDAESLGKAPTPGVAPESVGSSYQCRMQTLNFCMGTDPGLEHLLVSSVPTPGSSTPSASHRAPLPLPADSKEPWVAGSFPVQGGSGYPLGLPPCLYRTPGMFFFE
What is the function of this protein?
Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters.  May have a role in the organization of the testicular vasculature.
What are the official names of this protein?
Forkhead box protein S1, Forkhead-like 18 protein, Forkhead-related transcription factor 10, FREAC-10, Transcription factor FKH-3.
What are the subcellular locations of this protein?
Nucleus.
Protein: SFU1_CANAL
Sequence: MPTSPTESIPNSSTKEQPILPKMLPTAKSPHTTPAQSPQNSDHHHHHQQTPPQPTDGQQCSNCGTTKTPLWRRAPDGTLICNACGLYYRSNNTHRPVNLKRPPNTIAVVKEEEGSCKGDGRCNGTGGSAACKGCPAYNNRIVAKKALEKSPKNDSSRAPIDKSLKRSTSTDATTEDESSLAIACFNCGTTITPLWRRDDAGNTICNACGLFYRLHGSHRPIKMKRPTIKRRKRNVSDKKSKDEVQMHSSDQSPIVASDPISPTPHNNENNNNVTNITTTTKTPTRSPHYYQPPPQYPYQHHPINSTTSSAINRLPPISYQSPYQTAPLSHSPMQSSSSYSPGASSVIPSSYYPPYSGSGRIPNGPGPVPGPPPPPPPTQSQPHHQQITTSPTSQSYGSLRAPIHITKRGYTPENIRLPSIQLTSSTSSNSETKLPPITNHSEKCCSNCAGPKSLAPMAIDFTASYRFNNIDSQTKLTKEDQNDSEGVSRDNDTRDENKPIKQEEHRSALSIGKLLNG
What is the function of this protein?
Transcriptional regulator of iron-responsive genes.  Represses expression of SEF1 and genes for iron uptake if iron is present.  Plays also a transcription-independent role in the direct inhibition of SEF1 function through protein complex formation and translocation to the cytoplasm, where SEF1 is destabilized.  Promotes gastrointestinal commensalism in mice.
What are the official names of this protein?
Suppressor of ferric uptake 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ZFAND_DICDI
Sequence: MQVDRDLDKVGVHCAIKDCNLLDFLPFICQGCQGQFCLEHKEEKEHKCPTPIVKIGGTTVTCDKCESILPVPVNCFEKDILSMHLRKGCPKKTTVNQHKCSFCPKMESIKIVCPNCKNNFCIKHRFERDHKCKPRVNPPLQQTISPHLQNLLSQLRNSKPVKTNS
What are the official names of this protein?
AN1-type zinc finger protein.
Protein: ACCA_VIBPA
Sequence: MSLNFLEFEKPIAELEAKIEALRDVSRHGGDSAIDLDKEIEQLEKKSLELKKKIFSDLGAWETAQLARHPLRPYTLDYVQHVFEEFDELAGDRAFADDKAIVGGIARLEGRPVMIIGHQKGRETKEKVRRNFGMPKPEGYRKALRLMEMAERFNMPIITFIDTAGAYPGVGAEERGQSEAIAKNLKVMSGLKVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRDSDKAPQAAEAMGLTAPRLKELELIDEIIEEPLGGAHRDHVKMAENMKATLLRQLEDLEQLDEESLRERRYQRLMNYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_SALEP
Sequence: MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARHKNVPFESGIDSVGTARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLARIGALDWTPARSRRERMNPETNSIANRQR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MODC_PSEU2
Sequence: MASPIEVRLQMAYPDFTVRTDLSLPGSGITALFGPSGSGKTTCLRCIAGLEKADQSFIRVHDEVWQDTEKGIFLAPYKRAIGYVFQEASLFAHLSVRDNLEFGMKRIPRQQRRIQLPQASELLGIDHLLQRNPDKLSGGERQRVGIARALLTSPRLMLLDEPLAALDTRRKSEILPYLERLHRELDIPMLYVSHAQDEVARLADHLVLLDAGNVLASGPIHETLARLDLPLAMGSDAGVVIEGTVSAYDQHYQLLTVTLPDSKLSMRVAHAQMQVGTLLRIKVQARDVSLNLQPDYQSSILNRLPVTVIEEALADNSAHVLVKLDAGGTPLLARITRYSSDQLNLHRGQSLWAQIKAVAVLA
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NBP35_DEBHA
Sequence: MAPSQVEDISKTELETPEHCPGPESEQAGKEDACNGCPNQSICSSQLPQGPDPDLPLINKRLSQIDHKILVLSGKGGVGKSTFTSMLSWALAADEDIEVGAMDLDICGPSLPRMLGAEGESIHQSNSGWSPVYVADNLGLMSISFMLPDADSAVIWRGAKKNGLIKQFLKDVNWGEHLDYLVVDTPPGTSDEHLSVTTYMKEVGIDGALIVTTPQEVALLDVRKEIDFCRKANIKILGLVENMSGFVCPNCKGESQIFRPTTGGGKKLCEDLKLPYLGAVPLDPRIGKACDAGESFFDSYADSPASSAILDVVDALRDQIEISLEKLNI
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.  Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NBP35, Nucleotide-binding protein 35.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRE_LISMO
Sequence: MSIEKQVAEQLLEIKAVFLKPNEPFTWASGIKSPIYCDNRLTLGFPKVRQFIAKSLAEKIKQTFGEIDVVAGTATAGIPHAAWVSDLLDLPMVYVRSKAKEHGKGNQIEGPISKGQKVVVIEDLISTGGSSLKAVEALEEAGAEVVGIAAIFTYGLAKGKQLLEESGTKLVTLTNYDELIEVALNENYVTGEDMETLKEWKKNPEKWGK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: ISPT_ALKCK
Sequence: MLERFSKWRQAFTDTEDEEPTSIDPQNIPRHVAIIMDGNGRWAKEKGLPRIAGHREGMKTVNKIVRAANTLNIEILTLYAFSTENWKRPKAEVEFLLKLPERYLKSELPTLIEENVQVRLMGSKDGLPSYTLHAVDEAIEKTKHNTGLILNFALNYGSRFELTSAMQQIAKKVQQGELMPEHITEETISAHLMSNHLRDPDLLIRTSGELRLSNFMLWQIAYSEFLFMDVYWPNFTEHHFYKAVLTYQNRGRRYGGV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: Y6720_DICDI
Sequence: MLFKTLISSINKSNEFSKININNSIENINIELNNQIHDKTVSLKTKKVYFTRPNFVSF
What are the official names of this protein?
Putative uncharacterized protein DDB_G0275639.
Protein: AROQ_CORP2
Sequence: MNILVLNGPNLDRLGKRQPEIYGRTTLADVEKLLVKRADALGVTVIVKQSNYEGELIDWVHEAADAGWPVIINPGGLTHTSVSLRDALAEIHDGAGFVEVHISNIHAREEFRHHSFLSPIARGVIAGLGVMGYELALEYLVLNSHS
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: L83L_ASFM2
Sequence: MDTSLKNNDGASEADNKNYQDYKDESGNINDVINAIKHNSMVDCCHKNYSTFSSEWYMNERKYDDIAEGPSPKKSVVHRCTII
What is the function of this protein?
May subvert the host innate immune response by interacting with host IL1B and interfering with its function.
What are the official names of this protein?
Protein L83L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus L83L family.
What are the subcellular locations of this protein?
Host cytoplasm.