PharMolix/UniProtQA huggingface dataset:
Protein: Q0092_YEAST
Sequence: MFMMNNNMFIMFMIMYNVMRVNITRCSRVMFTTFYMITNKYIYIFM
What are the official names of this protein?
Putative uncharacterized protein Q0092, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PROB_SACD2
Sequence: MSKRQLVKQSRRWVIKIGSALLTNNGRGLDREEMAVWVKQMAALSKRGYEVVLVSSGAVAAGMTRLGWAERPKALHELQAAAAVGQSSLIQAYEQEFQKYSIKTAQILLDHDDLSNRQRYLNARSTLRTLTKLGVIPIVNENDTVVTDEIRFGDNDTLGALVANLIEADTLCILTDQKAMFDSDPRQNALAKMLIERSAFDPGLDAMAGDGGALGRGGMISKVRAARLAARSGANTIVVGGKVFDVIPRVASGEILGTLLYSESQPIAARKRWLAGNMQPRGRLTLDDGAVKVLREQGKSLLPVGVRAVEGYFTRGELVLCEDTAGREIARGLVNYSSDETNKIKGASSSRIDSLLGYKDYDELIHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_BACCZ
Sequence: MSNRFAVILAAGKGTRMKSKLYKVLHPVCGKPMVQHVVDQVSQLGLQKLVTVVGHGAEMVQEQLGNVSEFALQAEQLGTAHAVDQAAGVLANEEGTTLVICGDTPLITAETMEALLQQHKEAGAMATVLTAYIEEPAGYGRIVRNENGHVEKIVEHKDANEKELAIKEINTGTYCFDNKALFASLSKVSNDNVQGEYYLPDVIEILKNEGHIVSAYQTEHFDETLGVNDRVALSQAEIIMKNRINRKNMVNGVTIIDPSNTYISADAIIGSDTVLHPGTIIEGNTVIGSDCEIGPHTVIRDSEIGDRTTIRQSTVHDSKLGTEVSVGPFAHIRPDSVIGDEVRVGNFVEIKKTVFGNRSKASHLSYIGDAQIGEDVNLGCGSITVNYDGKNKFKTVIGNGVFIGCNSNLVAPVTVEDGAYVAAGSTITENVPSKALSVARARQVNKEDYVDQLLNKKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KA12O_SCOPC
Sequence: MRLAIILLLMTTIVLTIGSPLHGAKCSSSNQCTRPCRYGGGTHGKCMNGRCRCYG
What is the function of this protein?
Blocks mouse voltage-gated potassium channels Kv1. 3/KCNA3 (IC(50)=0. 3-30 nM), when the channel is expressed in Jurkat T cells or in HEK293 cells (PubMed:31890149).  Also shows a weaker inhibition on mKv1. 2/KCNA2 (IC(50)=56. 9 nM) and mKv1. 1/KCNA1 (IC(50)=485 nM) (PubMed:31890149).  Probably through the inhibition of both Kv1. 2/KCNA2 and Kv1. 3/KCNA3, the toxin also reduces the free calcium concentration in Jurkat T cells, inhibits the activation of Jurkat T cells and reduces the release of inflammatory cytokines interleukin-2, showing a strong immunosuppressant effect (PubMed:31890149).
What are the official names of this protein?
Potassium channel toxin alpha-KTX 12 Sp2, KTX-Sp2.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 12 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NU4M_PHOVI
Sequence: MLKIIIPTMMLMPLTWMSKPNMIWINTTAYSLLISLISLSFLNQLGDNCMSLSLLFFTDSLSAPLLALTTWLLPLMLMASQFHLSKEPLTRKKLYITMLILLQLFLIMTFTATELIMFYILFEATLVPTLIIITRWGNQTERLNAGTYFLFYTLVGSLPLLVALLFIQNNMGTLNFLMIQLWAQPLPSSWSNTLLWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRITVLLSPLTNFMAYPFMMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIMAILIQTPWSYMGATALMIAHGLTSSMLFCLANSNYERTHSRTMILARGLQVLLPLMAAWWLLASLTNLALPPTINLIGELFVVMASFSWSNITIILMGTNIIITALYSLYMLTTTQRGKYTYHIKNIKPSFTRENALMTLHLMPLLLLSLNPKIILGPIY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: METK_SHIB3
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATTFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_BURMA
Sequence: MEKFNVHTGVVAPLDRENVDTDAIIPKQFLKSIKRTGFGPNAFDEWRYLDHGEPGQDNSKRPLNPDFVLNQPRYQGASVLLARKNFGCGSSREHAPWALQQYGFRAIVAPSFADIFFNNCYKNGLLPIVLTEQQVDHLFNDTYAFNGYQLTIDLDAQVVRAPDGREYPFEITAFRKYCLLNGFDDIGLTLRHADKIRQFEAERLAKQPWLDNRLVG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: HPT_RABIT
Sequence: MRALGAVITLLLWGQLFAADFGNEVTDIADDSCPKPPEIANGYVEHLVRYQCKNYYRLRTEGDGVYALNSEKQWVNKAVGEQLPECEAVCGKPKHPVDQVQRIIGGSLDAKGSFPWQAKMVSRHNLVTGATLISEQWLLTTAKNLFLNHTENATAQDIAPTLTLYLGRRQLVEIEKVVLHPNYSEVDIGLIKLKDKVPVNERVMPICLPSKDYTEVGRVGYVSGWGRNSNFTYTDHLKYVMLPVADQDKCIQHYENSTVPENKIPKNPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSTFAIHDLQQDTWYAAGILSFDKSCTVAEYGVYVKTFNILDWIQKTIASN
What is the function of this protein?
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine.  Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage.  Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response.  Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity).
What are the official names of this protein?
Haptoglobin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IR3IP_BOVIN
Sequence: MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSIAIVLLLLFG
What is the function of this protein?
Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size.  Required for secretion of extracellular matrix proteins.  Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors (By similarity).  Acts as a regulator of the unfolded protein response (UPR) (By similarity).
What are the official names of this protein?
Immediate early response 3-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the YOS1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SECA_WOLSU
Sequence: MITQLTRKIFGTKNDKLVKKYRQRAQKINELEAKYQVMSDEALKSAFTSLKESVQKGEKSLDDVLYDSFAITREASKRVLGMRHFDVQLVGGMVLHEGRIAEMKTGEGKTLVATLAVALNAMKGEGVHVVTVNDYLAKRDATEMGVLYSFLGYSVGVITGDLYGDSERLEQYSSDVVYGTNNEFGFDYLRDNMKYSLEEKVQKSHAFAIVDEVDSILIDEARTPLIISGPANRKLDNYKIANSVALSLQKEKHFTVDEKNRVILLTEEGIREAEKGFGVDNLYSIENAILSHHLDQALKANHLFAIDKDYVINNGEVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVEIKEESQTLADITFQNYFRLYKKLAGMTGTAQTEASEFLQIYKLEVISIPTNVTVMRKDLNDLIYKTEREKFNAVIQKIKELNQKGQPVLVGTASIEKSELLHSLLQKERIPHTVLNAKQHAKEAEIIKDAGKKGAVTIATNMAGRGVDIKIDDEIRSLGGLYIIGTERHESRRIDNQLRGRSGRQGDPGASQFYLSLEDNLLRIFGSDKIKNIMDKLGLAEGEHIESGLVTRSVENAQKKVESMHFESRKHLLEYDDVANEQRKAVYKFRNELLDKSHDISHRIEDNRRDSLLNLLSKADILEGVEKEEYDLDRLLALFTEEYNTPISKELLEGKEYEALLLTLESHLKESYETKMSLVDENQKHDIERLIYLQVLDNAWREHLYLMDNLKTGIGLRGYNQKDPLVEYKKESYNLFIELIENIKFESMKALHSIQLRTKEEQEERQRAQEAAMQRLLSEMNAEANANLQFSHQPQSEVKVSRNDPCPCGSGKKYKNCCGQSGPKKGLLAQA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: YB95_SCHPO
Sequence: MKLSFILSTLVAGALAYNEFSAPGPNAVLQEGGGVNTVSWSNLTSSTVTLTLYRGGNSALTPIETIASDIDNTGTYLWNIATYYEAADDYLLGLSFDGGETYSQYFTLQACSTCTISTSSLSYSGTISSTSIAPSMIGTRTSSSYFITSSSSTPSSSSSSSSSSPSSSSSKSSSSSKSSSSSSSSSKSSSSSSSSSKSSSSSSSSSKSSASPSSSKSSSKFSSSSFITSTTPASSSSSGAIVSNAKTASTDDSSSASSATSSVSSVVSSASSALSASASSASASVSSSASSDASPALKTGINALVAVGVVSAIALFL
What are the official names of this protein?
Uncharacterized serine-rich protein C1E8.05.
Protein: CUE_DROGR
Sequence: MAYIDQKHNTFWDDFAIALRDKIVFLNSTWGEIHASAHRFEDLSALAFDEAEEMIYFSDQTHQNGSIFALRRDDSTPIVVQRTGNDSVEGLAYDPLNRNLFWADMRQQKIFFSSVDTLATELPKVLVDLSGEGGQPDGIAVDICRRQLYWTNGNIKSASVERIGLDGKGRQTIISADIDMPRGIVVDQLSDRIFWVDNKVGIFFAIESARLDGSDRQVVVKGKHQDPKHLAINEDAIYWTDRMDKAVWSYPKPTYSQEVTNVTQAEPELAKPFSKEKAYGIVTRTGFYQRLQKDAHCASIVKKVKQQLNTRLNNRTHIRSAEGDRISQLEREHCLNGASFMSRGEFCICPVGFKGARCEISECHNYCVHGTCEISDAGFPKCYCQAEFYGERCEYHKCNGHCLNSGHCSMDKESDAMRCECRPNFGGERCEHNLTEQCAIYCQHPETQLPVSCLDFCEEWSNSNDTATITEYQTAGQCGPAPPVQGPLIIVIVLGLVTTSGLVALTVHGVRLIYKPKRPRIKKTFVVRKQARLNSSSDTPLTNRPLTTEQCEITIENCCNMNICETPCFDPKLVEQTFSSRDRKAPCVKEDKKILIHSMEDNLLS
What is the function of this protein?
Has a role in spermatogenesis and oogenesis.
What are the official names of this protein?
Protein cueball.
What is the protein family that this protein belongs to?
Belongs to the cueball family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: F110B_RAT
Sequence: MPTETLQTGSMVKPVSPAGTFTSAVPLRILNKGPDYFRRQAEPNPKRLSAVERLEADKAKYVKSQEVINAKQEPVKPAVLAKPPVCPGAKRVLGSPTLKVFGNHAKTESGVQRETLKLEILKNIINSSEGSSSGSGHKHSSRNWPPHRDTTELHRHSFAESLKVYPTPGRGSPQESSSHVSRRLLEQSAESFLHVSHSSSDIRKVTSVKPLKAIPCSSSAPPLPPKPKVAAMKSPDADQVEPACGVSRRPSLQRSKSDLSDRYFRVDADVERFFNYCGLDPEELENLGMENFARANSDIISLNFRSASMISSDCEQSQDSNSDLRNDDSANDRVPYGISAIERNARIIKWLYSIKQARESQKVSHV
What are the official names of this protein?
Protein FAM110B.
What is the protein family that this protein belongs to?
Belongs to the FAM110 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: DXR_VIBCM
Sequence: MRKLTILGATGSIGASTLKVIAQNPQQFSIVALVAGVNVAKMYQLCQQWRPKYAVMATASAASELQGLLKNQAMATEVLYGEEAMCQVAALDDVDTVMAAIVGAAGLLPTMAAVKAGKRVLLANKEALVMSGQLFIDAVAQSGAELMPVDSEHNAIFQCLPTEIQTQLGRCDLSQHGIDHILLTGSGGPFRYSDLATLDSVTPEQAIAHPNWSMGPKISVDSATMMNKGLEYIEAKWLFNTSREQLKVLIHPQSVIHSMVQYQDGSVIAQLGEPDMATPISYAMAYPERVTAGVPALDFTRLQQLTFMEVDFARYPCLQLAMDACFLGQHATTSLNAANEVAVDAFLKRKIRFTDIALINDQVLSKVCATNTQLHCRDLESLLELDTMARHFAHQVLKERQA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: LT_POVBA
Sequence: MDKVLNREESMELMDLLGLERAAWGNLPLMRKAYLKKCKEFHPDKGGDEDKMKRMNTLYKKMEQDVKVAHQPDFGTWNSSEVPTYGTEEWESWWSSFNEKWDEDLFCHEDMFASDEEATADSQHSTPPKKKRKVEDPKDFPSDLHQFLSQAVFSNRTLACFAVYTTKEKAQILYKKLMEKYSVTFISRHMCAGHNIIFFLTPHRHRVSAINNFCQKLCTFSFLICKGVNKEYLLYSALTRDPYHIIEESIQGGLKEHDFNPEEPEETKQVSWKLITEYAVETKCEDVFLLLGMYLEFQYNVEECKKCQKKDQPYHFKYHEKHFANAIIFAESKNQKSICQQAVDTVLAKKRVDTLHMTREEMLTERFNHILDKMDLIFGAHGNAVLEQYMAGVAWLHCLLPKMDSVIFDFLHCVVFNVPKRRYWLFKGPIDSGKTTLAAGLLDLCGGKALNVNLPMERLTFELGVAIDQYMVVFEDVKGTGAESKDLPSGHGINNLDSLRDYLDGSVKVNLEKKHLNKRTQIFPPGLVTMNEYPVPKTLQARFVRQIDFRPKIYLRKSLQNSEFLLEKRILQSGMTLLLLLIWFRPVADFSKDIQSRIVEWKERLDSEISMYTFSRMKYNICMGKCILDITREEDSETEDSGHGSSTESQSQCSSQVSDTSAPDSENPHSQELHLCKGFQCFKRPKTPPPK
What is the function of this protein?
Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation.  Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA.  Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.  Participates in the modulation of cellular gene expression preceeding viral DNA replication.  This step involves binding to host key cell cycle regulators retinoblastoma protein RB1/pRb and TP53.  Induces the disassembly of host E2F1 transcription factors from RB1, thus promoting transcriptional activation of E2F1-regulated S-phase genes.  Inhibits host TP53 binding to DNA, abrogating the ability of TP53 to stimulate gene expression.  Plays the role of a TFIID-associated factor (TAF) in transcription initiation for all three RNA polymerases, by stabilizing the TBP-TFIIA complex on promoters.  Initiates viral DNA replication and unwinding via interactions with the viral origin of replication.  Binds two adjacent sites in the SV40 origin.  The replication fork movement is facilitated by Large T antigen helicase activity.  Activates the transcription of viral late mRNA, through host TBP and TFIIA stabilization.  Interferes with histone deacetylation mediated by HDAC1, leading to activation of transcription.
What are the official names of this protein?
Large T antigen, LT, LT-AG.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RL222_ARATH
Sequence: MSRGGAAVAKGKKKGVSFTIDCSKPVDDKIMEIASLEKFLQERIKVGGKAGALGDSVTITREKSKITVTADGQFSKRYLKYLTKKYLKKHNVRDWLRVIAANKDRNLYELRYFNIAENEGEEED
What are the official names of this protein?
60S ribosomal protein L22-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL22 family.
Protein: KGUA_PSE14
Sequence: MTHITGTLYIISAPSGAGKTSLVKALMDAQQEPQHGAQAKIRVSVSHTTRAMRPGEVNGVNYNFVDRAEFVRMIEHGDFLEQAEVFGNLYGTSQSHLQQTLDEGHDLILEIDWQGARQVRAQMPQARSIFILPPTQQALRQRLTNRGQDSDEIIEARMREAVSEMSHYNEYEYVVVNDDFAGALEDLKAIFRANRLTQQHQQEQYSELFQELLA
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y028_NPVAC
Sequence: MVFNVYYNGYYVEKKFSKEFLIHIAPDLKNSVDWNGSTRKQLRVLDKRAYRQVLHCNGRYYWPDGTKFVSHPYNKSIRTHSATVKRTDSSHRLKSHVVDKRPRRSLDSPRLDGYVLASSPIPHSDWNEELKLYAQSHGYDDYDDNLEDGEIDERDSLKSLNNHLDDLNVLEKQ
What are the official names of this protein?
Uncharacterized 20.4 kDa protein in IAP1-SOD intergenic region, ORF14.
Protein: POTA_STRT2
Sequence: MTNPIIAFQNVSKVFEDSGTQVLKDINFELEEGKFYTLLGASGSGKSTILNIIAGLLDATSGDVLLDGKRINDIPINKRDVHTVFQSYALFPHMNVFDNVAFALKLKKVPKKEIEERVKEALKMVQLDGYQKRSIQKLSGGQRQRVAIARAIINQPRVVLLDEPLSALDLKLRTEMQYELRELQKRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQSGTPVDIYDEPINHFVATFIGESNILPGVMIEDYLVEFNGKRFESVDGGMRPNEPVEVVIRPEDLQITLPEEGKLQVRVETQLFRGVHYEIIAYDNLGNEWMIHSTRKAIEGEIIGLDFMPEDIHIMRLNETEEEFDARIEEYVEMEEPEDGLIHAIEEERHEENS
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS13_STUS1
Sequence: MARIAGVNIPDNKHTVISLTYIYGVGRTRAQEICAATGVNPAAKIKDLSDEQVELLRGEVGKFIVEGDLRRDVNMKIKRLMDLGCYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PSTB_CARHZ
Sequence: MLSDVKIKVRDLNLYYGNFQALKNISLDIYKNEVTALIGPSGCGKSTFLRTLNRMNDLIPGVRIEGSILFDGVDIYKENFDVVELRKRVGMVFQSPNPFPKSVYENVAYAPKIHGLKDKRKLDEIVEKSLRGAALWDEVKDRLHKPATGLSGGQQQRLCIARALAIEPEVLLMDEPTSALDPISTMRIEELIQELKKKYTIVIVTHNMQQAARISDRTAFFLNGELIEMDRTEVIFTKPRDRRTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ENGB_MYCGE
Sequence: MDAHFLKSASDLKDCPQDNIPEICFMGRSNVGKSSLINAFFKKKLAKTSATPGRTQLLNYFEYKDKRFVDLPGYGFAKINKNKKDFITNLLTQFLNFRSNLVGVVLIVDSGVVTVQDQEVVKIILQTGLNFLIVANKFDKLNQSERYFSLKNIANFLKVNFDKCVFASTKTHHNLALVHKKIFELFVEDER
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: COBT_ECOBW
Sequence: MQILADLLNTIPAIDSTAMSRAQRHIDGLLKPVGSLGKLEVLAIQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAEQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYTQELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: IF12_BORPE
Sequence: MSKDDVIQMQGEVLENLPNATFRVKLENGHVVLGHISGKMRMHYIRILPGDKVTVELTPYDLTRARIVFRSK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 2.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_BORBU
Sequence: MSKYEFIKIEKKWQEFWDNNKTYKVEEDPSIPKEKRLYILDMFPYPSANGLHVGHPEGYTATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGFAYDWDREIRTHEENYYKWTQWIFLQLYKKGLAYVKEMPVWYCPELGTVLANEEIIQTSDGPKSERGSYSVEKKYLRQWVLKITKYAERLLDDLEELEWPESVKEMQRNWIGKSTGVEIEFEIEGHSDKIKVFTTRPDTIFGITYLVIAPENKLIEKITKNNFKQNVLKYVKHEELKSDLNRTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYVLGTYGTGAVMGVPAHDERDFQFAKKYQLKILPVISKSGKNEILEKAFVDDGISINSPNEFNNLKNSEVKDKVIKWLTKNKKGKEKVAYKLRDWIFSRQRYWGEPIPILFDKLGNAIPLEENDLPLKLPEIANYKPSGTGESPLSRIKDWVNVKDMGFTRETNTMPQWAGSCWYYLRYLDPKNSKEFANKKKIEYWMPVDLYIGGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITSFSYQKENGVLIPNDQVIEKDNKFFDKKDNKEVTQVIAKMSKSLKNVINPDDIIKEFGADSMRIYEMFMGPLTDSKPWNTKGIIGVFRFLNKIWNLREKELSKENPPREIISELHKVIKKVTEDTEKLNFNTAISAMMIFINELLKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGELPSLFKNSKWPKFDESLIIKGKKEIVLQINGKIKDKILLNKETGEKELKEIAMENSKIKSNLLNKKIVKIIVIKNKLVNIVIK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFA_HAES1
Sequence: MIDYILLIISTALINNFVLVKFLGLCPFMGVSKKIETAIGMGLATMFVLTVASLCAYLVEHYLLTPLHANFLRTLIFILVIAVVVQFTEMVIHKTSPTLYRLLGIFLPLITTNCAVLGVALLNINLAHNLTQSVIYGFSASLGFSLVLVLFAALRERLTAADIPLPFRGASIALITAGLMSLAFMGFSGLVRV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SODL_MONPZ
Sequence: MAVCIIDHDNIRGVIYVEQVHGKDKVLGSVIGLKSGTYSLIIHRYGDISRGCDSIGSPEIFIGNIFVNRYGVAYVYLDTDVNISTIIGKALSISKNDQRLACGVIGISYINEKIIHFLTINENGV
What is the function of this protein?
Virion protein with no enzymatic activity.
What are the official names of this protein?
Cu-Zn superoxide dismutase-like protein.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: YAJC_BRUA2
Sequence: MFVTPAFAQASGSVVGPDMLMSILPFILIFVIMYFLIIRPQRTQMKKRQEMLNSVRRGDTVVTGGGIVGKVLKVVDDNELELEIADGVRIRVVRATLMDVRVKGEPVADNKNK
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC, Immunogenic membrane protein YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.