PharMolix/UniProtQA huggingface dataset:
Protein: NAGZ_YERPE
Sequence: MGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVAVDQEGGRVQRFRDGFTRLPAAQYFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMKTTGKHFPGHGAVTADSHKETPHDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQELGFEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQLTRLYHSGQFDRQTLMASSRWQQANKALTALSERWDAHKQTLGQ
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_RUBXD
Sequence: MDATVFTKCERCKQPVYEKDLRARFNVCPNCEFHYPLPAPERVRLLTDAGSFEERDGELAAGDPLGFEGYPDRLRSARKKTGLGDAILSGVGEIGGRRVALAVMDFRFIGGSMGSVVGERVARTVELARAEGLPLVTVSASGGARMFEGIYSLMQMAKTSVALSRFMEGSKPYISILTDPTFGGVTASFATAADIIIAEPGARVGFAGARVIEQTTKERLPEGFQTAEFQREHGMVDRIVHRLALKGDLERLLGFVG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_ALBFT
Sequence: MPLPLQPMPEPLIKPLADAAPGENPVHVAANLQTFLALDFGLKRTGFAVGNRLLRTAQPQGTIAAEGDARFVKIALQLKEWQPDALVVGVPFHPDGAAHENTLRARRFARQLQGRFKLPVFEVDERYTTTEALGRGARDADAMAACIILEQFLRSI
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDC2_ARATH
Sequence: MALILPCTFCTSLQKKNFPINRRYITNFRRGATTATCEFRIPVEVSTPSDRGSLVVPSHKVTVHDRQRGVVHEFEVPEDQYILHSAESQNISLPFACRHGCCTSCAVRVKSGELRQPQALGISAELKSQGYALLCVGFPTSDLEVETQDEDEVYWLQFGRYFARGPIERDDYALELAMGDE
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions (Probable).  Mediates alternative electron partitioning in conditions of acceptor limitation at photosystem I (By similarity).
What are the official names of this protein?
Ferredoxin C 2, chloroplastic, AtFdC2.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NADK_ACET2
Sequence: MLKIGIIPNEDKDEELKYTRILVDSIKKCGGTAIVCDDIALKLGDKESNINEDNIVDMSDVMVCLGGDGTFLKAARMTVVKGKPLLGVNLGKLGFLADVDKNDIENAVKRLVEDKFTVDERMMLDTVIVRDGKIIAEDIVLNDVVISRGAISRILHLKTYINDAFMDLYPGDGLIISTPTGSTAYSLSAGGPLVEPDVDLIICTPICPHLLYSRSFITTADRVIKVVVAESSSHEAMVTVDGQNGYEVRGGDVIITKKSRIRMPMVRLNGKNFFDVLRGKIYDRGESMK
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_NOVAD
Sequence: MECGVETLLPLVVGYVLGSVPFGLILTRLTGAGDLRAIGSGNIGATNVLRTGKKGLAAATLLLDLGKGLAAVLIVRHVWPGAEALAALAAVLGHCFPVWLRFKGGKGVATLMGVSLALAWPIGLVYAVTWLGVLFLSRISSLGGMSAAVVAPVAAAVLGYAPYVPVLALLALLVLYLHRENIARLRAGTEPKVGSRK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y467_VIBCH
Sequence: MNLTNHFLVAMPSMKDPYFKRSVIYICEHNQDGAMGLMINAPIDITVGGMLKQVDIEPAYPQSHQENLKKPVFNGGPVSEDRGFILHRPRDHYESSMKMTDDIAVTTSKDILTVLGTEAEPEGYIVALGYSGWSAGQLEVELTENSWLTIEADPELIFNTPVHEKWQKAIQKLGISPAQLSSDAGHA
What are the official names of this protein?
UPF0301 protein VC_0467.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RL3_STRA5
Sequence: MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETDGYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEAGDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAGRMGGNRVTVQNLEIVQVIPEKNVVLIKGNVPGAKKSLITIKSAVKAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: MNME_HISS2
Sequence: MSRDTIVAQATPIGRGGVGILRVSGPLAQQVAEQVLGKTLTPRMANYLPFKDSDGSVLDQGIALYFKAPNSFTGENVLELQGHGGQIVMDLLLKRILQIDGIRLARPGEFSEQAFLNDKLDLAQAEAIADLIEASSEQAARSALKSLQGEFSNKINELVDSVIYLRTYVEAAIDFPDEEIDFLADGKIETHLREIIAKLAKVKNEAKQGAILREGMKVVIAGRPNAGKSSLLNTLAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDATDEVEKIGIRRAWDEIEQADRILLILDSTENQVELDLVRSEFMAKLPPHIPLTIVRNKADLSGEAEVLNEQNGLTVISLSAKTQKGVDLLRQHLKQSMGYQVCTEGGFLARRRHLEALEQADIHLQAGLIQLTEFYAGELVAEELRIVQHHLSEITGQFTSDDLLGNIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_ENTFA
Sequence: MLPEEFRQLLAAKGIELTDQQMTQFDQYFHLLVEWNEKMNLTAITEEKEVYLKHFYDSVSLAFFEDFASDKAICDVGAGAGFPSIPLKIVFPSLNVTIVDSLNKRITFLTELVNQLGLANVSLYHDRAETFGQKAEFRGAFDYVTARAVARLNVLSELCLPLVKKEGYFLALKASKSEEEINEAKPAIATLGGQFQKEVGFTLPITADERHIVVIQKKKETPKKYPRKPGLPNKQPIK
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDB_STAAC
Sequence: MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKGHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: RECA_MAGMG
Sequence: MDRQKALEAAVSQIERAFGKGSIMKLGGKDQVVETEVVSTRILGLDVALGIGGVPRGRIIEVYGPESSGKTTLALHIIAEAQKKGGTCAFVDAEHALDPSYARKLGALDELLISEPDAGEQALEIADTLVRPGAVDVLVVDSVAALVPRGELEGEMGDNHMGLHARLMSQALRKLTGSVSKSKTIVIFINQIRMKIGVMFGNPETTTGGNALKFYASVRMEIRRVGAIKDRDEVVGNQTRVKVVKNKLAPPFKVVDFDIMYGEGISKMGELIDLGVKANVVKKSGAWFSYNSTRIGQGRENAKQFLRDNPAMAAEIEGAIRQNAGLISEALAAVPDLDGTPVAE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPEC_LACLC
Sequence: AEQLVIDYSEKSVIVQKEKLIAKNTDENLKLIFTDGVQQKEINQFISKSQAFVAGLMHDIGGVYPNHQRVEKAELFGIELLTEEREFPLIIHQKLSKYLAREHFKITDENILSAIECHTTLKENFTELDLIVFLADKISWDGGDNAPFKEGLLTALSVNLQSAALYYIDFIINDGLKVAHPWLLEAKKDLENQLS
What are the official names of this protein?
Uncharacterized protein in pepC 5'region, ORF 2.
Protein: Y2102_MYCTU
Sequence: MSSTWYPPPSRPRPVEGGIKARSTRGAIAQTWWSERFIAVLEDIGLGNRLQRGRSYARKGQVISLQVDAGLVTALVQGSRARPYRIRIGIPAFGKSQWAHVERTLAENAWYAAKLLSGEMPEDIEDVFAGLGLSLFPGTARELSLDCSCPDYAVPCKHLAATFYLLAESFDEDPFAILAWRGREREDLLANLAAARADGAAPAADHAEQVAQPLTDCLDRYYARQADINVPSPPATPSTALLDQLPDTGLSARGRPLTELLRPAYHALTHHHNSAGG
What are the official names of this protein?
Uncharacterized protein Rv2102.
Protein: TPS3_CANOD
Sequence: MNPVSLLSLSGERRSANWKPSSWDSNQIHQSLKSDFNDLQEKWHTELKQAVEQMLEAVAEPLQKLTLIDDIQRLGVAYRFEKQIDDALSSIYSNYAAEVSSKKDLLAASLYFRLLRQHGCYVSPDIFIQFKDEAGQFKASLGDDVEGLLSLYEASYLGIKGETILDDAKAFSTSTLENLMPHVEADIASRISHALHLPLHWNMRRMEARLYIDVYRENKKRRNDNLLEFARLDFNMLQVIHQRDLKDVSFWWDFLDLPRKLGFIRDRLMESFIFSVGLNFEPQFSECRKAATKDILLITVLDDIYDIYGSMDEVEIFNNAVNRWDLGAVDELPEYMQLCYLGLLNSVNELAYVTMKDTGRNVLDFLKKLWKRHFNAAVKESRWFHRQYTPTLEEYMENAQISIGAPLVLTHAYVKMLKYMPNEDVNHVDKYLKLISMMCYVFRLYDDWGTSKAEIERGDVPKAIQCYMHEAKVSEEIAREHIKNIINERWKELNEECLKATDLNRKFVAAVLDALRAAAFFYHDRDGFGEPDHKFKSQAMALFSQQV
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile organic compounds (PubMed:25956881).  Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into alpha-bergamotene (PubMed:25956881).  Does not use (2E)-geranyl diphosphate (GPP) as substrate (PubMed:25956881).
What are the official names of this protein?
Sesquiterpene synthase TPS3, Alpha-bergamotene synthase TPS3, Terpene synthase 3, CoTPS3.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11A_YEAST
Sequence: MSAKAQNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFGIDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTTKEDTVSWFKQKYDADVLDK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11-A, L16, Large ribosomal subunit protein uL5-A, RP39, YL22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The SYO1-uL5-uL18 complex is transported into the nucleus by KAP104.
Protein: S66A3_HUMAN
Sequence: MEAALLGLCNWSTLGVCAALKLPQISAVLAARSARGLSLPSLLLELAGFLVFLRYQCYYGYPPLTYLEYPILIAQDVILLLCIFHFNGNVKQATPYIAVLVSSWFILALQKWIIDLAMNLCTFISAASKFAQLQCLWKTRDSGTVSALTWSLSSYTCATRIITTLMTTNDFTILLRFVIMLALNIWVTVTVLRYRKTAIKAE
What are the official names of this protein?
Solute carrier family 66 member 3, PQ-loop repeat-containing protein 3.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LEUC_STAEQ
Sequence: MGQTLFDKVWKKHVLHGKEGEPQLLYIDLHLIHEVTSPQAFEGLRIQNRKLRRPDLTFATLDHNVPTIDIFNIKDEIANKQITTLQQNAKDFGVHIFDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPKNLKININGSLPAGVYAKDIILYLINQYGVDFGTGYALEFTGETIKNLSMEARMTICNMAIEAGAKYGLMQPDETTFNYVKGRPYATDFDSSMAWWKELYSDDDAYFDKVIELDVTNLEPQVTWGTNPEMGVSFSNPFPEIKNANDQRAYDYMGLHPGQKAEDIKLGYVFLGSCTNARLSDLIEASHIIKGQQVHPNITAIVVPGSRTVKKEAEALGLDKLFKDAGFEWREPGCSMCLGMNPDQVPEGVHCASTSNRNFEGRQGKGARTHLVSPAMAAAAAINGKFIDVRKVVV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: GIA2_GIAIN
Sequence: MPKLSQIVADMKQAIDAKDEAQIAFIASEYSADARQRIAQGYRDQYGKELPDDIKKALKGGSEESLLMDLFSDRHEVRAQHIRDALSGKNDHMAFFDTVILCTPEDWHETVAAYTRMFKKPLVEDFMKDVGRKENWCLFMEKWMAHERTSREGSPDEEAEKLNKAFSESDHDYISSFMAGVPPEEYKSINTSFKSLTGKGIDQAFATIYTGTDYYSLYCAHFALLGMHKLAAYLVNCACNDKGDEKRMRRITGMMVDKCLAAKYAYKTYGSMKADVERCFDKRMAPILCTLWRLRE
What is the function of this protein?
Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst.  They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.
What are the official names of this protein?
Giardin subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the annexin family. Giardin subunit alpha subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Most likely in the edges of the ventral disk microribbons.
Protein: G3P_USTMA
Sequence: MSQVNIGINGFGRIGRIVFRNSVVHNTANVVAINDPFIDLEYMVYMLKYDSTHGVFNGDISTKDGKLIVNGKSIAVFAEKDPSNIPWGQAGAHYVVESTGVFTTIDKASAHIKGGAKKVVISAPSADAPMYVCGVNLDAYDPKAQVVSNASCTTNCLAPLAKVIHDKFGIVEGLMTTVHATTATQKTVDGPSAKDWRGGRAAAANIIPSSTGAAKAVGKVIPSLNGKLTGMAFRVPTTNVSVVDLTARLEKGASYDEIKAEVKRASENELKGILGYTEDAVVSQDFIGNSHSSIFDAAAGISLNNNFVKLVSWYDNEWGYSNRCLDLLVFMAQKDSA
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_THERP
Sequence: MVDVCLLGTGGMMPLPDRWLSALLVRCEGHVVLLDCGEGTQISWRYTGWSFRDLDAIVFTHLHADHVAGLPGILYALAFADRQEPVRIIGPVGTAQVVAALRSIVPTLPFPVETLELSGTSELELPGGLLLRALPVTHRIPCFAYTLHRPRGRRFDPQRAQALGIPMTLWHRLQRGETVEFAGQLLTPDLVLGPPRRGITVAFVTDTRPTPELPGFVAGADLLVCEGMYGDTALLPRAIERGHMLMQEAAELARAASVERLWLTHFSPSLTDPEAWLPAIRAIFPASEIGPVHQTVTLRYRDA
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: RUVB_WOLWR
Sequence: MKSISCGKEYTEDVRNINIRPEQLDDFVGQKDLIQNLKVFINAAQTRTEALDHVLLYGPPGLGKTTLAQIVSKELRVSFRATSGPLLSKAGDLAAVLTTLNAKDVLFIDEIHRLNRSIEEVLYTAMEDFCLDILVGEGPSTRTLRIDLPPFTLIGATTRLGLLSAPLRDRFGIPLHLEFYSFEELVNIIKRGARVLSAEIEEDAAREIACRARGTPRIALRLLRRIRDFVEVKDDKKITYEVADSVLLKLGVDKMGLNKLDMNYLRFLFNTSGPVGIDTISIALSEDVGNIEETVEPYLIKISFVKRTPRGRVLTDQAKEYLSL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: IHFA_ECOL5
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RPOB_STRPG
Sequence: MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSGLKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVGRYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKFVYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYFLNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIVWLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQHNGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIADGPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: GR08A_DROME
Sequence: MSGHLGRVLQFHLRLYQVLGFHGLPLPGDGNPARTRRRLMAWSLFLLISLSALVLACLFSGEEFLYRGDMFGCANDALKYVFAELGVLAIYLETLSSQRHLANFWWLHFKLGGQKTGLVSLRSEFQQFCRYLIFLYAMMAAEVAIHLGLWQFQALTQHMLLFWSTYEPLVWLTYLRNLQFVLHLELLREQLTGLEREMGLLAEYSRFASETGRSFPGFESFLRRRLVQKQRIYSHVYDMLKCFQGAFNFSILAVLLTINIRIAVDCYFMYYSIYNNVINNDYYLIVPALLEIPAFIYASQSCMVVVPRIAHQLHNIVTDSGCCSCPDLSLQIQNFSLQLLHQPIRIDCLGLTILDCSLLTRMACSVGTYMIYSIQFIPKFSNTYM
What is the function of this protein?
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.  Required for sensing and avoiding L-canavanine, a plant-derived insecticide.
What are the official names of this protein?
Gustatory receptor 8a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GNDS_HUMAN
Sequence: MVQRMWAEAAGPAGGAEPLFPGSRRSRSVWDAVRLEVGVPDSCPVVLHSFTQLDPDLPRPESSTQEIGEELINGVIYSISLRKVQLHHGGNKGQRWLGYENESALNLYETCKVRTVKAGTLEKLVEHLVPAFQGSDLSYVTIFLCTYRAFTTTQQVLDLLFKRYGRCDALTASSRYGCILPYSDEDGGPQDQLKNAISSILGTWLDQYSEDFCQPPDFPCLKQLVAYVQLNMPGSDLERRAHLLLAQLEHSEPIEAEPEALSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPSWPSPVVAENGLSEEKPHLLVFPPDLVAEQFTLMDAELFKKVVPYHCLGSIWSQRDKKGKEHLAPTIRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSALQSNSIHRLKKTWEDVSRDSFRIFQKLSEIFSDENNYSLSRELLIKEGTSKFATLEMNPKRAQKRPKETGIIQGTVPYLGTFLTDLVMLDTAMKDYLYGRLINFEKRRKEFEVIAQIKLLQSACNNYSIAPDEQFGAWFRAVERLSETESYNLSCELEPPSESASNTLRTKKNTAIVKRWSDRQAPSTELSTSGSSHSKSCDQLRCGPYLSSGDIADALSVHSAGSSSSDVEEINISFVPESPDGQEKKFWESASQSSPETSGISSASSSTSSSSASTTPVAATRTHKRSVSGLCNSSSALPLYNQQVGDCCIIRVSLDVDNGNMYKSILVTSQDKAPAVIRKAMDKHNLEEEEPEDYELLQILSDDRKLKIPENANVFYAMNSTANYDFVLKKRTFTKGVKVKHGASSTLPRMKQKGLKIAKGIF
What is the function of this protein?
Functions as a guanine nucleotide exchange factor (GEF) activating either RalA or RalB GTPases and plays an important role in intracellular transport.  Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap (By similarity).  During bacterial clearance, recognizes 'Lys-33'-linked polyubiquitinated TRAF3 and subsequently mediates assembly of the exocyst complex (PubMed:27438768).
What are the official names of this protein?
Ral guanine nucleotide dissociation stimulator, RalGDS, Ral guanine nucleotide exchange factor, RalGEF.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes mainly in the peripheral region of the cytoplasmic membrane in oocytes and in preimplantation embryos until the 8-cell stage. Between the late 1-cell and the early 2-cell stages, nuclear localization becomes stronger. After the 4-cell stage, not detected in the nucleus.