PharMolix/UniProtQA huggingface dataset:
Protein: CC020_MOUSE
Sequence: MNQIKSNRELYLQYSASAPKLLAHVSKLLIFCRNSGISIPKGIRNIFEFTWEELINDPAVPTASEIQDLVVTFGTPTVVLAEVIPVQVLPMQKKQPPPAPPPTLMPAATSGGKYVPPTSTSAKLMPNGQNTLHKFQRQSIHLLTELLSLKMKAMVESASAGANPLDITKRFVEASQLLHLNAKEMAFDCLTGTVGKSCLSTAQLGKESSMNISAMGVNTPYQLVYQTSTACLSFSLCTGKESRKKDIGAKPKPVDDVSPQPVRARTPPENTVVELPDPCPEAREKLQDMCRHIEAERILWRGRNASCPMIFRNYRSRISSHLMLASKGDSHHPLTTGTQITASAPHQPSSQHAQMGRHSQEWKGPKKPIKLHYTFYDGSSFIYYPSGNIALLQIPTCCRGKPITCLFNDMPNTFLALFNAEGLGCVYYNLKNCCPYVLVLDEEGGITNDQKGYIVHRWSWASKTETLLSLEYKVNEQMKLTVLGQDSITVTFTSMNETVTISVSPKSCPHNVLHDKRPVRRISLMDEKVSKTNRALAEIKKRFQKTVTQFMNSVLLAAGLFTLEYPNPKETETSRVKLKPGSNQDRIRKTSLYQGENHMRIQSARQDSIINETLKEDSILTSLAHVQKKNGKVQVKVLPRGKRREVRSPTRWAASPSDCPLVLRRLILKEDIRAGCKCIVKAPLVSDLELERFLSAPRDPNQVLVFGIMSSQDPTLTAQLQWLMDTLYSHLQQGRSSPCIQCRHDPYRLLRYDLDSPLQKDPPLMVKKFAVIHGMVLMFAGGKLLFGGCVLNGYGFSKQNLLKQIFRAQQDCKMGYFLPDNYKFKHDAFKASRIAKPCGLSSRGVPSQFLGLETEPSMSTYVTNLDDTESTKKPPSDDYEGSVSSVALVDKIEKEPPPSPEKVKPPEIELQPFTKMRRSSKKTAGFKKLNSKK
What are the official names of this protein?
Uncharacterized protein C3orf20 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL27_BUCAT
Sequence: MAHKKAGGSTRNGRDSNAQRLGVKCFGGQLISAGSIIVKQRGTKFHPGKNVGCGKDHTIFAIVKGKVEFKKKGLKKRTYINIIN
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SFTPD_MOUSE
Sequence: MLPFLSMLVLLVQPLGNLGAEMKSLSQRSVPNTCTLVMCSPTENGLPGRDGRDGREGPRGEKGDPGLPGPMGLSGLQGPTGPVGPKGENGSAGEPGPKGERGLSGPPGLPGIPGPAGKEGPSGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSTGAKGSTGPKGERGAPGVQGAPGNAGAAGPAGPAGPQGAPGSRGPPGLKGDRGVPGDRGIKGESGLPDSAALRQQMEALKGKLQRLEVAFSHYQKAALFPDGRSVGDKIFRTADSEKPFEDAQEMCKQAGGQLASPRSATENAAIQQLITAHNKAAFLSMTDVGTEGKFTYPTGEPLVYSNWAPGEPNNNGGAENCVEIFTNGQWNDKACGEQRLVICEF
What is the function of this protein?
Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins.  Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response.  May participate in the extracellular reorganization or turnover of pulmonary surfactant.  Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
What are the official names of this protein?
Pulmonary surfactant-associated protein D, PSP-D, SP-D, Lung surfactant protein D.
What is the protein family that this protein belongs to?
Belongs to the SFTPD family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
Protein: FABZ_CAMHC
Sequence: MIDINEILEILPHRFPFLLIDRVIDLQPGISIKAYKNVTFNEQIFQGHFPGHPIYPGVMIIEGMAQAGGVLAFKSTTDEDLSNKVVYFMTIDKAKFRQPIRPGDRLEYRLNVLKHRGRIWVLKGEALVDDKVAAEAELQAMIMDK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3L234_OPHHA
Sequence: KTLLLTLVVVTILCLDLGYTTKCYITPDVKSETCPDGENICYTKTWCDVWCGSRGRRVDLGCAATCPIVKPGVNINCCSTDNCNPFPKRS
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin OH-34.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: THIG_COXBN
Sequence: MWAIGGVQLNSRLLLGTAQYPSPQLMSDAVKAAGVEIITVSLRRQLSPQKENYFWDLLRSLPCHLLPNTAGCSSVKEAVNTARAARELFNTHWIKLEIIGDEYTLQPNPFELVNAATILVKEGFEVFPYCTEDLILCQRLVDAGCRVLMPWAAPIGSGRGLMNTYALQLLRERFPKNILIIDAGLGRPSHAAQVMEMGFDAVLLNSAVALAMDPVVMAAGFAKAVEGGRLGYEGGMIKARNVAKATTPLIGKPFLIEKP
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMBRL_XENLA
Sequence: MEVNQDVSVREQIFHDWVRECIICSLLFSTLYLLSYIVITKFKKHADFATVDVEDAAVNRIALWMCTFTLAVSVGAVLLLPFSIISNEVLLSVPHNYYIQWLNGSLIHGLWNLVFLFSNLSLVFLMPFAYLFTEAEGFAGSKKGVMSRVYETTVVLLLLTLLVFGIVWVASAIFDDDSAGRESLYDLWEYYLPYLYSGISLFGVLLLLLCTPFGLSRMFSVTGNLLVKPRLLENLEEHLSCTAFEEAAISRKISTKASCWLNLNMEALQKRLLAIQSHRITLEMRRRASPWQRNLVYPLAMLLLLALTGITVLIVCVNVLELLIDEAAMPKGIQGSQLGKVSFSVFGSFGAAVQVILIFYLMASSVVGFYSSPLFIQLLPQKQNTPMTKIIGNCVSLLILSSALPVFSRTLGITRFDLLGDFGRFNWLGNFYLILLYNMMFAGLATLCLVKKFTWAVQAELIRAFGLDRLPLSVKKIRSQGKA
What is the function of this protein?
May play a role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway (By similarity).  May act as a LCN1 receptor (By similarity).
What are the official names of this protein?
Protein LMBR1L.
What is the protein family that this protein belongs to?
Belongs to the LIMR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PTH_SULAC
Sequence: MKMAVLVRTDLDMGKGKIAAQVAHAAVSLVLEIVQKRSKAEWKEWLEMWINQGQPKIVLKVKNLDELLEKYNKALQSGLPATIIQDAGKTQIEPGTITCAGIGPGPEEMIDNITGDLKLL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_LEUCK
Sequence: MNNKVLQTLEYDKIKLQLNDFLSTPTGLQEANELQPVSDVDLINHWLAETADAVLIDRLKGGIPLSKLSDITPHLKRLNIEASLSATELSEMSLVLRNTSTIASFFEQMQDEAIGESLRVLPEQAKNLVTLPDITRQIQIAIDSSGRLNDEASYELKHVRDRINGTEQAVKNQMQAYTRGKTAQYLSDPIVTIRSDRYVLPVKAEYRSQFGGVVHDQSQTGQTLYVEPQAVVTLNNKLSELRVQEQAEEQRVLQELSATLAPHTEEIANNVTILGHFDFVNAKARLAARLDAMQPMVNTENKVDLQQAWHPLLDKDLAVANDIALGDGYKAIIITGPNTGGKTITIKTLGILQLMAQSGLFITTKRPSTVGVFHEIFADIGDEQSIEQSLSTFSSHMANIVSMIDRIDDKTLVIFDELGAGTDPAEGAALAIAILDKVASLGAFVIATTHYPELKLYGYNRPETLNASMVFDVSTLKPTYQFLMGVPGQSNALAIAKRLGFGDDVIGAATALTSDADQDLNQMIADLVAQRDAVKQHDVALSEQLKATEKQSEALSEQQRQLEKERAKIVLDAKNEANHIVAATKKQAEQMISEIRKARLNAGQSAGELSEQDLQAKKRQLDGLRQNSSLEKNKILQKAKRAKQLAAGDEITVQSYGQQGTLIKQHSNGQWEVEMGILKMLVDEDDIVKTEATAKAQQSKAKQKQQKIVKTKTASGSARATAKSRLDLRGVRYEAALAELDRYLDTAVLANLGTVEIIHGKGTGALRQGVTEFLRSDRRVKAYHFANANAGGDGATIAELS
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: RNPH_YERPY
Sequence: MRPADRAAQQVRPLTLTRNYTKHAEGSVLVEFGDTKVLCTATVEEGVPRFLKGQGQGWITAEYGMLPRSTHSRNAREAAKGKQGGRTLEIQRLIARSLRAAVDLKKLGEFTITLDCDVLQADGGTRTASISGACVALADALNKLVASGKLKANPMKGLVAAVSVGIVKGEALCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHEELLALLDLARGGIETIFQAQKAALES
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PSBE_PROM0
Sequence: MIMAAGSTGERPFFEIITSIRYWIIHAVTLPAIFIAGFLFVYTGLAYDAFGTPRPDSYFQSSESKAPVVTQRYEAKSQLDLRTK
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CDPK4_PLABA
Sequence: MGQEMSTQSDMQNENQKGNKRNLKGSQGKNGLKERSTSISKEIVKNSFNNSKLRPGMFIQNSNVVFNEQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDVLHGTYDEKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAKDLIKKMLMYTSAVRISARDALEHEWIRLMTSKDNVNIDIPSLELSITNIKQFQSTQKLAQAALLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGDDTTDLDNAAIEVEVDQILSSIDLDQNGYIEYSEFLTVAIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQLFGLGDVSSDCWKTVLKEVDQNNDGEIDFKEFRDMLIKLCNY
What is the function of this protein?
At the end of male gametogenesis in the mosquito gut, required to initiate axoneme motility, cytokinesis and subsequent exflagellation.
What are the official names of this protein?
Calcium-dependent protein kinase 4, PbCDPK4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. Membrane; Lipid-anchor. Chromosome. Note=A small fraction of the protein localizes to membranes and to chromatin.
Protein: RHAT_ECOBW
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPNFWAYYSSFSLSTRLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLISTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKSLIIHNVLLSTLGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVAANIVGIGMAN
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HPPA_XANAC
Sequence: MLEHYGLWLALGCAVLAIVYGIVSARWVVAQPSGNARMQEIAAAIQEGARAYLNRQYLTISVAGAVLFVLVGLFLSWYTAIGFALGAVLSGLAGYIGMNVSVRANVRTAEAARHGIGKAMDVAFRGGAITGMLVVGLGLLGVAGYFAVLQGMGLPLEQNLHALVGLAFGSSLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETYAVTVIATMLLGSLTLADTGSHAVLYPLVLGGVSIIASIVGAAFVKVKDGGSIMGALYKGVIVSGVLAALAYWPITQSLMRDNIHGATALYACALIGLVLTGLIVWITEYYTGTQYTPVQHVASASTTGHGTNIIAGLGISMKSTALPVIAVCAAIWGAFHFGGLYGIAIAATAMLSMAGMIVALDAYGPITDNAGGIAEMAELPPEVRNITDPLDAVGNTTKAVTKGYAIGSAALAALVLFADYTHNLQAANPDQVYAFDLSDHTVIIGLLIGGLIPYLFGAMAMEAVGRAAGAVVEEVRRQFRELPGIMAGTAKPQYDRAVDMLTRSAIGEMIVPSLLPVVVPIIVGLLLGPRALGGLLIGTIVTGLFLAISMTTGGGAWDNAKKYIEDGHFGGKGSEAHKAAITGDTVGDPYKDTAGPAINPLIKIINIVALLLVPLL
What is the function of this protein?
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane.  Generates a proton motive force.
What are the official names of this protein?
K(+)-insensitive pyrophosphate-energized proton pump, Membrane-bound proton-translocating pyrophosphatase, Pyrophosphate-energized inorganic pyrophosphatase, H(+)-PPase.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FBID_SANKS
Sequence: MSAEQQAVVSAEQQAVVSAEQPAVVSADQPAVTWTVVVPVKVTSQAKTRLAGDLSPTQRVELVRAMVVDTVAAARATPTVDRVVVVTDDPDVVADLSADEPAGTDAERRADPSAENRASTSAQHPCLRAHLDVVPEPSPAAGLNAAIRAGVASARSGGGLAAVSVAVLLGDLPALRPGDLGAALEAASAHHRAVVTDADGSGTTLLTARSGVELYPAFGPGSAAEHAARGHVVLDVADVPAVSGLRQDVDLARDLAAVAALGPGPRTTEVLDRWARLGEGSSAA
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: AB35G_ORYSJ
Sequence: MDAAAEMQKVVSLRRGGGGSSSRGAASMWWSADNGVFSRSRASSSGEDGEDDEEALRWAALEKLPTYDRVRRAVLPVVEEGGGGGEAGKKVVDVLSLGPQERRALLERLVRVAEDDNERFLLKLKERIDRVGIDIPTIEVRFEHLEAEAEVRVGNSGLPTVLNSMTNKLEGAANALGILPNKKQTMPILHDVSGIVKPRRMTLLLGPPGSGKTTLLLALAGRLGKDIKFSGQVTYNGHQMEDFVPQRTAAYISQHDLHIGEMTVRETLSFSARCQGVGSRFDMLTELSRREKAANIKPDADIDAFMKASAMEGQETNLITDYILKILGLDICADTMVGDDMVRGISGGQRKRVTTGEMLVGPANALFMDEISTGLDSSTTFQIVKSLRQAIHILGGTAVISLLQPAPETYDLFDDIILLSDGQIVYQGPREGVLEFFELMGFKCPERKGVADFLQEVTSRKDQKQYWMQHDKPYRYVPVKDFASAFQSFHTGKSIANELATPFDKSKNHPAALTTSRYGVSAMELLKANIDREFLLMKRNSFVYIFRACQLMVVSAIAMTVFFRTKMHRDSVTDGVIFMGALFFSVMMIMFNGLSELPLTIFKLPVFFKQRDLLFFPAWTYTIPSWILKIPMSFIEVGGFVFMSYYVIGFDPSAGRFFKQYLLMLAINQMAAALFRFVGGAARNMIVANVFGSFMLLIFMVLGGFILVREKVKKWWIWGYWISPMMYAQNAISVNEFLGHSWDKVLNNSLSNETLGVQALRSRGVFPEAKWYWIGFGALLGFIMLFNGLFTLALTYLKPYGKSQPSVSEEELKEKQANINGNVLDVDTMASSTNLAIVDNTETSSEIADNSQPTQRGMVLPFAPLSLTFDNIKYSVDMPQEMKAHGIVEDRLELLKGVSGSFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIEGNITISGYPKKQETFARVSGYCEQNDIHSPQVTVSESLLFSAWLRLPKDVDSNTRKMFIEEVMELVELKPLRDALVGLPGVNGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFEAFDELFLMKRGGEEIYVGPLGHQSSELIKYFEGIKGVSRIKDGYNPATWMLEVSTISQEQALGVDFCDIYRKSELFQRNKALIQELSTPPPGSSELYFPTKYSLSFLNQCLACLWKMHLSYWRNPPYNAIRLFFTTVIALLFGTIFWDLGGKTGKSQDLFNAMGSMYSAVLFIGVLNSQSVQPVVSVERTVFYRERAAGMYSAFPYAFGQVAIEFPYTLVQSIIYGIIVYSMIGFKWTAAKFFWYLFFMFFTFLYFTFYGMMAVGLTPSYHVASIVSSAFYGIWNLFSGFIIPRPKVPIWWRWYCWICPVAWTLYGLVASQFGDIMTPMDDGTPVKIFVENYFDFKHSWLGVVAVVIVAFTMLFAFLFGFAIMKLNFQKR
What is the function of this protein?
May be a general defense protein.
What are the official names of this protein?
ABC transporter G family member 35, OsABCG35, Pleiotropic drug resistance protein 11, OsPDR11.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DCUP_MYCGI
Sequence: MNTRRELPESPYLAAAAGRKPHRVPVWMMRQAGRSLPEYRELRAKNTMMQACFDADLITEITLQPVRRHGVDAAILFSDIVVPLRAAGIDLDIVPDVGPVIAHPIRTAADVATVSPLRRETVAPVATAIGQLTAALGDVALIGFAGAPFTLASYLIEGGPSRNHERTKAMMLGETETWNALMAALTDVTIEFLRVQLDAGVDAIQVFDSWAGTLSLADYRAYVLPHSARVFEALAGYGVPMTHFGVGTAELLGAMSEAVSGHGVPAVVGVDWRTSLTDAAARVRPGCALQGNLDPVVLLAGWPVVERAVRAVVEDGRRAVDAGATGHVFNLGHGVLPATDPAIITDAVALVHQL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_CHESB
Sequence: MKIFGFFGKRASAPMARERLQVLLAHERASLGKSDLVAILREEIIAVIAKHIQVDSEKVNVKMDRDEKVSTLEIDVEIPLQAGGRAA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RL3_RHOJR
Sequence: MTDTKIKGILGTKLGMTQVFDENNRVVPVTVVKAGPNVVTQIRTEERDGYSAVQLAFGAIDPRKVNKPTSGQFAKAGVTPRRHVVELRVADTSEYEVGQELTAEVFEDGAYVDVTGTSKGKGFAGTMKRHGFAGQGASHGAQAVHRRPGSIGGCATPGRVFKGMRMSGRMGSDRITTQNLSVHKVDAENGLLLIKGAIPGRKGGLVIVKSAVKGGARA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ADAB_ASPNC
Sequence: MAFRIPFAQSFWQEYLSGQEANLPRLPEVEQVTETVMRILGGNPGRMQLQGTNTYLVGTGKFRILIDTGQGEASWIEALTKQLEANGLEISHVLLTHWHGDHTGGVPDLITYNPELSSRVYKNTPDLGQQAIHDGQKFHVEGATIRAVFTPGHAFDHMCFLLEEENALFTGDNVLGHGYSVVEDLGTYMTSLTRMADLNCALGYPAHGTRIEDLPAKMKEYIQHKESRMRQVLAALERSRARMTATGGGRRAGALTFPELINSMYGGIPDEIEQALTPFLSQVLWKLAEDRKVGFEGEPSQRRWFAVGPPAATAVRL
What is the function of this protein?
Lactamase-like protein; part of the gene cluster that mediates the biosynthesis of the linear tetracyclic TAN-1612 neuropeptide Y receptor antagonist (PubMed:21866960).  The decaketide backbone of TAN-1612 is synthesized by the non-reducing polyketide synthase adaA via condensation of one acetyl-CoA starter unit with 9 malonyl-CoA units.  The FAD-dependent monooxygenase adaC then performs hydroxylation at C2 while the polaketide chain is still attached to the NRPKS adaA (PubMed:21866960).  The alpha-hydroxylation step at C2 appears to be crucial for the following C18-C1 Claisen cyclization and release of the C9-hydroxyl version of TAN-1612 from the NRPKS adaA, two steps performed by the lactamase-like protein adaB (PubMed:21866960).  Finally, the O-methyltransferase adaD performs the C9 O-methylation to complete the biosynthesis of TAN-1612 (PubMed:21866960).
What are the official names of this protein?
Lactamase-like protein adaB, 2-acetyl-2-decarboxamidoanthrotainin biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: NUOG_ECOLI
Sequence: MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGACRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISIDDEEAKQFRESVVEWLMTNHPHDCPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRYYKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRKWDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLKDRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGEENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALAVRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAPVEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIISGTNAGSLEVIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGRADAVVVLENDLHRHASAIRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNEGRAQRFFQVYDPAYYDSKTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPELAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDIDTMFTFSMEGNNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENGLDYFTSVPARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQSRMPQPYIKLNPADAAKLGVNAGTRVSFSYDGNTVTLPVEIAEGLTAGQVGLPMGMSGIAPVLAGAHLEDLKEAQQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit G, NADH dehydrogenase I subunit G, NDH-1 subunit G, NUO7.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: PDE1_SCHPO
Sequence: MHAALEIKEAEFQTDQVVGLVENSFTLYSLGQNGGPLESCCSSHLISDGAFQEIISLDGGSHLSALVELIQSKHLSVDSWSSITKYDNYTVENESYAKAWHLSEQRIKTFLITHCHLDHIYGAVINSAMFGPQNPRTIVGLNYVIDTLKKHVFNNLLWPSLDKAGFINFQVVEPSMYTSLTTTLSILPFPVNHGSSFGQELKSSAFLFRNNLSDRYFLAFGDVEPDMVASEPLNIHIWRACSSLIAQRKLSHILIECSTPDIPDTLLFGHFCPRHLVNELCILQSLVQSYGVIMPTLTCLLTHLKSHPLQSANPADVILEQLESLSSKSSLSVTFKILQRGQFYKF
What are the official names of this protein?
3',5'-cyclic-nucleotide phosphodiesterase, PDEase.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-II family.
Protein: STAR3_DANRE
Sequence: MPSAVDYSELGGSLPAIASLNASYSQASLSLPSPYYCPLPPGERKAFSDVRRTFCLFVTFDLLFITLLWIIELNISKSIWNSLENEVVHYNFKSSFFDIFLLAVFRFLCLQLGYAAFRLRHWWVIAITTLVTTAFLIAKVILSDLFSQNAFGYVLPITSFVVAWLETWFLDFKVLTQEAEDERVYLAAVNAACEPAPLICPRPVSDGQFYSPPESLAGSEDDLDEEGLGRRAVTEQEKAFVRQGREAMAVVEQILTQEENWKFEKTNELGDAVYTLEIPFHGKTFILKGLLQCTAELVYQEVILQPEKMVQWNRTVSVCQILQRVDDNTMVSYDVSAGAAGGVVSPRDFVNVRRVERRRDCYISAGMATNHNSKPHHSRYVRGENGPGGFVVLKSSSNPSVCTFIWVLNTDLKGRLPRYLIHQSLAATMFEFMSHLRQRINEVHVSYR
What is the function of this protein?
Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes.  Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum.  Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes.
What are the official names of this protein?
StAR-related lipid transfer protein 3, MLN64-like protein, START domain-containing protein 3, StARD3.
What is the protein family that this protein belongs to?
Belongs to the STARD3 family.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Note=Localizes to contact sites between the endoplasmic reticulum and late endosomes: associates with the endoplasmic reticulum membrane via interaction with VAPA and VAPB.
Protein: ARGJ_LACTC
Sequence: MRVSSALLQKAAKTVDKYSLYVPKSGVFPKGFKVASLASGVKKNGNRDLGIILNTNKSRPSNAAAVFTTNRFKAAPVLVSKQVLDGSSGEGVNAIVANSGCANAVTGELGMQDAQKVAGQVNAHIGKENSTLVMSTGVIGQRLQMDKISKGINTLFDQKQFGSDFNSWLNLAKSICTTDTFPKLISSKFQLSDGTEYTLTGISKGAGMICPNMATLLGFIVTDLPIKASTLQAMLTAAVNRSFNCISVDGDMSTNDTICMLANGAVDTFVIDEASPDFEQVKSQVTEFAKQLAQLVVRDGEGATKFVTVNVKNSANFKDARIIAETISNSMLVKSALYGQDANWGRILCAIGYSKLENLASLDESKINVSFIATDNSSPRELKLIANGVPQFDIDENRASEILALPDLEILVDMGTGSEECQFWTCDLSHEYVTINGDYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL31_CLOBL
Sequence: MREGIHPEYNHDVVVKCACGNTFTTGSTNKELKVEICSKCHPFFTGKQKIVDAGGRVDKFMKKFNLSNEDVK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.