PharMolix/UniProtQA huggingface dataset:
Protein: DOX1_PERHD
Sequence: MDYLILMICIVVSGLLLYSSRTSKMKLPPGPPGLPIVGNLFDLGSLPHRSLAKLAKLHGPVMCLRMGRLRVVVISSDSAAKEVLQTSDTLFCNRFVYDSLTASQHHTFSMALLPPTALWKSLRKISASQLFTNARMNASQHLRRKQLEDLLSYVESCSRSGTAINIAQAAFNTSVNLLSKTFFSVDLIDPSSSNSVEFKEMVWQIMLESGTPNLADYFPVLRRIDPQGNRRRMKIQFEKILDLFNTMIRQRLDEKGGCFDEINDTLDALLKINQDNSEELDLSVIPHLLLDLFVGGSESTSSTVEWAMALLFSNPEKMKKAKEELETVVGKGIAVKEEDTGRLPYLQAAIKETFRMHPPTPFLIPRKTDSDVDLCGFTVQKGSQVIVNAWAIGRDPSLWENADTFEPERFLGMEIDVKGRNFELIPFGAGRRICPGLPIAMRMLTLMVANLINCFEWRLEGGAAPETLDMSDKIGFTLQRAHPFRVIPTSIIQGCDVSTALNN
What is the function of this protein?
Catalyzes the conversion of drimenol to drimendiol, a precursor of the sesquiterpenoid polygodial (PubMed:28258968).  Polygodial has been shown to be an antifeedant for a number of herbivorous insects (Probable).
What are the official names of this protein?
Drimenol monooxygenase, Cytochrome P450 76AJ1, Drimenol oxidase 1, PhDOX1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RPOC_STRPF
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQEYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFNKSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDAGREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDSQRHKIMVTTVGKILFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDGLEINVPFKKKNLGNIIAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVEEINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHPETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAVITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEGSIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGDTDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSAEAVFTAEAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RUVB_CLOD6
Sequence: MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQLSIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAAILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTLIGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKRSRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTIIEKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIPYPNEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TRMD_SACD2
Sequence: MSSSSGSAVNIAIVTLFPEMFAAITESGISRRAVEQGLVKLSFFNPRTYTTDKHQTVDDRPYGGGPGMVMRVEPLAKALLAAKQWHSEQRAEQALPNTAKETVIYMSPQGAQLNNQAVDTMAASGDFTIIAGRYEGVDQRFIDAFVDQEWSIGDYVLSGGELPAMVLIDALIRKLPGALGDAQSAEQDSFENGLLDCPHYTRPEELADAWQTSVDDRRVPAVLLSGDHKKIELWRLKQSLGRTWERRPDLLNKLDLDQSQRNLLTEYQQQKLSCSSSDD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_PAEAT
Sequence: MSPMARTAPVPAATDPAIIRNFCIIAHIDHGKSTLADRMLQYTGVVKQRDMKAQYLDRMDIERERGITIKSQAVRMPWELDGNSYALNMIDTPGHVDFTYEVSRSLAACEGAVLLVDAAQGIEAQTLANLYLAMENNLTIIPVLNKIDLPAAQPEKYAAELANLIGGDPEDVLKVSGKTGVGVEALLDKIVRDLPAPVGDPNAPARAMIFDSVYDTYRGVVTYVRVVDGMLHPRERIQMMSTRATHELLEIGVSSPEPTPSKGLGVGEVGYLITGVKDVRQSKVGDTVTNLAKPASESLSGYADAKPMVFSGLYPLDGTDYPVLRDALEKLMLNDAALVYEPETSAALGFGFRVGFLGLLHLEITRERLEREYNLDLISTAPNVEYEVTLEDKKVIHVTNPSEYPTGKISEVREPMVSATILAPNEFVGSIMELCQSRRGQMRGMDYLSEDRVELRYWIPLAEIVFDFFDLLKSKTRGYASLDWKADGEQVADLVKVDILLQGEQVDAFSAITHRDKAYAYGVMMTGKLRELIPRQQFEVPIQAAIGSRIIARESIRAIRKDVLAKCYGGDITRKRKLLEKQKEGKKRMKMVGRVEVPQEAFIAALTTDESKDKAKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PDXB_PSET1
Sequence: MKILADQNMPLVEQYFADIGEVERFDGRQLTADQLIDVDVLLTRSVTQVNNELLAHANKLSFVGTATIGVDHIDTQLLNDKNIAFSSAPGCNAIAVAEYVISSLYALSQENARPLNNQTIGIVGVGSIGSCLAQKLQALNLTVLLCDPIKHAQGLLNEHVALDQLLAQSDIVTFHVPLIKSGEHKTLHMMDKARLKALKPGLTLINASRGDVIDNQALLEVMQAGADLDLVLDVWENEPTILIELLEHVRYASVHIAGHTLEGKARGTQILYQKFCELKGIEATKSLDEFLPVPAITQATLGQSFNEADIARLVHLIYDVRRDDGILLRDLANNGFDSLRKNYPVRREFSTLTIQGDSSQLAALAQLGFTVAN
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAHY_LARTR
Sequence: MASLSSQSKLLATPYSFPYHTKPSRVSLRRVSCKASNDNKDKPNDQEKTFSIDRRNMLIGLGGLYGASNVFPSNQSTLAAPIQPPVLPDSCHPPEDLAEGVNVLCCPPDVKDPIDFQMPSNPSRLRIRPAAHLADPTYIEKYKKALAAMKALPQNDPRSFYQQANIHCAYCNGAYDQVGFPDVNIQVHHSWLFLPFHRWYLYFYERILGSLIDDPTFAIPFWNWDAPKGMHMPHMFIDPNSPLYDAKRNPAHFPDTIVDLDFSSGEAPSHNPRQIGNNLSIMYKQVVRAKKARLFHGRPLQAGSFPDESGDGSLEGTPHGNIHLWSGDPRQSNFENMGNFYSAGRDPLFYAHHANVDRMWYIWKNSLGRKDYKKKDWLNAGFLLFDENAQPVRVYVRDALDERKLGYAYQEVDIPWINSKPKPRKANPWPNRLRSKATTTTKLINKFPLTLDSTVSFEVKRPKKSRSKSEKEDEEEVLVIEKIKHEPQFPLKFDVYINDEDEDPSAADQTEFAGSFVNVPHFHRHGDKKDKRQTTNLSIGISEVLDELDVDGDDSIVVTLVPRVGSGQITIGGAKIEFVRDEED
What is the function of this protein?
Enantio-specific polyphenol oxidase involved in aromatic ring hydroxylation.  Involved in the biosynthesis of the creosote bush 8-8' linked lignans.  Has a strong preference for the 3' position of (+)-larreatricin.
What are the official names of this protein?
(+)-larreatricin hydroxylase, chloroplastic, Polyphenol oxidase.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: MRPA_BACSU
Sequence: MQLLHLAILSPFLFAFIIPFLAKYAKRVHTGWFVLILPVLLFIYFLPMIRMTQSGETLRSVLEWIPSLGINFTVYIDGLGLLFALLITGIGSLVTLYSIFYLSKEKEQLGPFYVYLLMFMGAMLGVVLVDNVMVLYMFWELTSLSSFLLIGYWYKREKSRYGAAKSLLITVSGGLCMLGGFILLYLITDSFSIREMVHQVQLIAGHELFIPAMILILLGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGIYVIARFSPIFAFSAQWFWIVSLVGLFTMVWGSFHAVKQTDLKSILAFSTVSQLGMIISMLGVSAAALHYGHTEYYTVAAMAAIFHLINHATFKGSLFMAVGIIDHETGTRDIRKLGGLMAIMPITFTISLIGTFSMAGLPPFNGFLSKEMFFTSMLRVTHFDLFNVQTWGVLFPLFAWIGSVFTFIYSMKLLFKTFRGNYQPEQLEKQAHEAPVGMLVPPVILVALAVSLFFFPNILSYSLIEPAMNSIYPTLLDGHEKFHVHISQWHGVTTELLMTAGIVVIGTIGYLSLNKWKGIYKLFPSKLTLNRLYDKLLTMMEKGSYRVTKQYMTGFLRDYLLYIFAGFIILIGGAFAIKGGFSFKTEGMAKIGVYEIILTLVMISATVATVFARSRLTAIIALGVVGYTLALFFVIFRAPDLALTQLVIETISVALFLLCFYHLPKLRLKTKTRTFRMTNFIISLGVGVIVTLLGIASSSQRTKDSIASFFVKHSHDLGGGDNVVNVILVDFRGFDTMFEITVLTIAALGIYSMIKTKVKEEGKSGE
What is the function of this protein?
Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis.  Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB.  MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance.  MrpA is required for initiation of sporulation when external Na(+) concentration increases.  Also transports Li(+) but not K(+), Ca(2+) or Mg(2+).
What are the official names of this protein?
Na(+)/H(+) antiporter subunit A, Mrp complex subunit A, Multiple resistance and pH homeostasis protein A.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MATK_LOLPR
Sequence: MEKFEGYSEKHKSRQQYFVYPLLFQEYIYAFAHDYGLNDFEPVEIFSCNNKKFSSLLVKRLIIRMYQQSFWMNSVNHPNQDRLLDYKIGFYSEFYSQILSEGFAIVVETPFSLRELPCPKEKEIPKFQNLHSIHSIFSFLEDKFVHLDYLSHIEIPYPIHLEILVQLLQYRIQDVPSLHLLRFFLNNYSNWNSFITSMKSIFLLKKENKRLFRFLYNSYVSEYEFFLLFLRKQSSCLPLAASGTFLERIHFSKKMEHFWIMYPGFFRKTIWFFMDPLMHYVRYQGKALFASKGTPFLNKKWKWYLINLWQYCFSFWTQPRRIHLNQLANSCFDFMGYLSSVPKSPFLVKNQMLDNSFLIDTLIQKLDTIVPATALIGYLSKAQFCTGSGHPISKPIWTDLSDWDILDRFGRICRNLFHYHSGSSKKRTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSAFLEEFFTEEELVFSLMFTKTTLCSFRGSHSERIWYFDIIRINDLVKPLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COF5_DICDI
Sequence: MESRIIEIDPNCVNEFEKLKKKYKIESIFLKLNDNFNLLYVEKTLSKISQDDFLESIPVDQPRLIIYKKYSNNKIIFIRWIPEIVQDTIEYSYSNASTAILELLIGINEYMEVKDLIQLSNL
What is the function of this protein?
Controls actin polymerization and depolymerization.
What are the official names of this protein?
Cofilin-5.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS21_SPHAL
Sequence: MQIIVRDNNVDQALRALKKKLQREGVYREMKLRRHYEKPSEKRARERAAAVRRARKMERKRMERDGIK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: BIOF_ALKMQ
Sequence: MNNVHELQFLKEKIQELKNDGVYRKLPILEGPNEAEIMLNGKKVINLSSNNYLGFANHPQIKKAAIDAVEKYGVGAGAVRTIVGNMDIHEELERVLAEFKREEAVMVFQSGFNCNAGTIQAVTEKGDLIISDQLNHASIIDGARLSRADKTVFKHADMDNLEQVLKENQDKYRNKLIITDGVFSMDGDIAPLPDIVELAEKYGAMTYVDDAHGSGVLGENGRGTVDHFGLHGRVDFTIGTLSKAIGVIGGYVAGSHTMKEWLSHRGRPLLFSTSLPPAAVGSIIEAVKLLMSTTEYTDRLWDNAKYFKEKISQLGFDIGHSGTPITPVIIGEEGKAMAFSKKLLENGVFVSGIIFPTVAKGTGRVRCMVTAGHTKEQLDRAVEVFKKVGQEMDLL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: RL13_SULTO
Sequence: MSEQLVVVNAENQILGRMATHIAKLLIQGKRVVVVNAEKAIISGPRARVVRGYSLIFSVRKFQNPEKNTIKRPRTPINIVKRTVRGMLPKNKSGKMMFKNLIVFIGIPAEYKDKQMIRFEDADVKRLKGKYITVGELSKLLGGFSQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PVK1_EUBSB
Sequence: GSSGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, EubSp-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SC5A7_MOUSE
Sequence: MSFHVEGLVAIILFYLLIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVLVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPLIFYPGYYSDKNGIYNQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVRNENIKLNELAPVKPRQSLTLSSTFTNKEALLDVDSSPEGSGTEDNLQ
What is the function of this protein?
Transmembrane transporter that imports choline from the extracellular space to the neuron with high affinity.  Choline uptake is the rate-limiting step in acetylcholine synthesis.  Sodium ion- and chloride ion-dependent.
What are the official names of this protein?
High affinity choline transporter 1, Hemicholinium-3-sensitive choline transporter, CHT, Solute carrier family 5 member 7.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell membrane. Synapse. Note=Localized at the neuromuscular junction.
Protein: KMO_XANOM
Sequence: MSPVSPRSLTLIGAGLAGCLLAILLSRRGWQITVYERRGDPRIKGYECGRSINLALAERGRHALRQAGAEELVMAKAVMMRGRMVHPLVGEPQLQRYGRDDSEVIWSIHRAALNVALLDLAEQAGARVHFYRRLHTVDFDAGYARFIDDRDDQPHEIHFQSLIGSDGAGSALRAAMQRKSPLGERTEFLDHSYKELEIPPLPGGGFRIEGNALHIWPRGRYMFIALPNDGGTFTVTLFLPNAGEPSFATTRNGDEAFALFARDFPDALPLIPQLKQHWEEHPPGLLGTLTLDRWHLDGRALLIGDAAHAMVPFHGQGMNCAFEDCVALADQLDAHDDLASAFAAFEAARRDDAGAIQQMALENYLEMRDRVDDPEFLLQRQLEQQLQARWPTRFVPHYTMVTFLRTRYSIALARSEIQREILVEATRGHSDLSRLDWAALETIVHARLEPLDGAH
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase, Kynurenine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
Protein: SYA_LISMO
Sequence: MKQLSSAEVRQLFLDFFKEKGHTIEPSAPLVPNNDPTILWINSGVATMKKYFDGSVIPDNPRMANAQKSIRTNDIENVGKTARHHTFFEMLGNFSIGDYFKEGAIVFAWEFLTSPKWIGFDPDKLYVTVYPEDEEAKTLWREKIGLSDDHIVEIEDNFWDIGIGPSGPDSEIFYDRGPAFGDDASDPELYPGGENERYLEIWNLVFSQFNHNPDGTYTPLPKQNIDTGMGLERMVSIIQDAPTNFETDLFMPIIREVEQIAGVKYGHSQENDVAFKVIADHIRTVAFAIGDGALPSNEGRGYILRRLLRRAVRYAKVLTINEPFMYKLVPVVGKIMNSFYPEVENQTDFIQKVIRTEEERFHETLNEGLAILETILKTAKETNEQVIKGADIFKLYDTFGFPVELTEEYAEDHGLKVDHAGFEAEMKEQRARARAARADVKSMQVQGELLANLTEKSAFVGYNSTEHVSEILYLIQNDTLVDEVAAGNEAQVIFKETPFYAESGGQVADKGTIESETGLAYVEDVQKAPNKQNLHRISVKEGVLKTGDTVKLAVDKVKRRETIKNHTATHLLHRALKDTLGEHVNQAGSLVSPDRLRFDFSHFGQITEEELTKMEEIVNEKIWEQINVVIEEMPIAEAKELGAMALFGEKYGDIVRVVQVGKYSIELCGGVHVRNTADIGLFKIVSETGIGAGTRRIEAVTGKEAYRFVTEQENTLKQAASLLKTTTKETPQKVELLQADLREVKRENESLLSKLASAASADIFESPEEIGGVKVIAKQVNAKDMNQLRQFVDNWKDKKIGGILVLGAVQGDKVNLISAVSEEAIKAGYHAGKLLKEVATRCGGNGGGRPDMAQAGGKNPAELGTALDYVSTWVKEQQA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA2_BACCR
Sequence: MEKLLIEGGRALNGTIRVSGAKNSAVALIPTTILADTPVTIGGVPNISDVKMLGDLLEEIGGKVTYGQEEEMVVDPSNMVAMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLDVVSVGATINIMLAAVRAKGRTVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYMILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGNRKLKVVDIKTLVYPGFPTDLQQPFTTLLTKAHGTGVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLLQGAKVKASDLRAGAALVIAGLMADGITEVTGLEHIDRGYENIVDKLKGLGANIWREQMTKQEIEEMKNA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VRET_DROME
Sequence: MESESSQDDWSAFDPMSREYYDQVGNRYTNESGQKLIMEAPLPPKDEKEQRATRQAKYPYLVVPKSSPYVTEKMLINFFGRALIKEMEFRRLSRVYFVYFENIASLETAQQRVQRYPNLIKCITGRPQKEREITSDPVTSTEPMPTPGPAISATERTPVNHNREVPISTGGQNHPEFFRPPLVTKDDYKRGSLLATNDPIQRYLNVKYEFALERHDIYKLKDETRIPQVVLHFRSGRTIPLSTVAVTEEDKTKSLLEDGVSKCVVCQNWTDTFCKLCKMPFCNASCFADVAEQHKQACGKGEILNLDEKVGRKYPKPGLPPSGSKVRITAFEQTNVVYVRSADIQIDIAYYTVLTEVMMLGKDASKLQSTPVCGQIVLYKFEGHMSRAMVLNVDNIKEIYVVFIDFGSVEVTQLERLYECSSYLAGLTCYPVAVKLRGVPRRFVGPNIREVMYELDQSLVFNIKYSSREYDTSKGMQVVVMTEIDINRSLNRLFKTILTPVEPSVSDLGYKEDCLPYIPLHCGKNINVVVMDNTFIQCGFIYCTSIDLAYEVTKMQRDIQEYGEKIAKCATYAPPINELCIAKYEGKWRRGLSVELVGDGYPSILFIDYGNIVPTHVTDIRPYPPQFIFPIMTTQLDLIGVPEKPTDEQIKWLDKNYPIGSVITCSEITFDEETNSYSTRIEKLQEFLSLD
What is the function of this protein?
Gonad-specific protein essential for germline development to repress transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process in both germline and somatic gonadal tissues by mediating the repression of transposable elements during meiosis.  Required for primary piRNA biogenesis in both germline and somatic gonadal tissues.
What are the official names of this protein?
Protein vreteno.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to Yb bodies in follicle cells and to the meiotic nuage, also named P granule, in germline cells.
Protein: RPPH_CROS8
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLQRKDVRILATTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLMSNDADINMQTSSTPEFDGWRWVSFWYPVRQVVSFKRDVYRRVMKEFASVVMPLQESAPPQRNPSPAWRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: GLPX_MYCTK
Sequence: MTAEGSGSSTAAVASHDPSHTRPSRREAPDRNLAMELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPECDFAVDPIDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMNKIAVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRPRHAQLIHDVRATGARIRLITDGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDAERRKALEAGYDLNQVLTTEDLVSGENVFFCATGVTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGDSSAVYPLP
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate.
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 2, FBPase class 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_PSYWF
Sequence: MPKTAMTDSTSKTSTNTASSDMAAEFDSTTARLNASLSKPQLNADGHLRHFLGIEGLSRAQLLAIIHKAESFFDDKGQLINSPELEGCTVMNLFFEPSTRTRTTFEVAEKRLGANVLNIDIARSSTQKGESLRDTLWNLQAMTADIFVVRHSASGAAHFMATEVTPDIAIINGGDGWHAHPTQAMLDMLTIHREAPRPFEELTVAIIGDIKHSRVARSDIAALKILGVKEIRVIAPRTLLPKGIERYGVKVFENIDEGVVDCDVLMGLRIQNERIGSPLMAASNEYFKKYGITPERVAKAKPDALVMHPGPMNRGVEIASSVADGPQSVILKQVNNGIAVRMAVLSMAMQGQREYQALRSST
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: LEAD_ADE02
Sequence: MRADREELDLPPPVGGVAVDVVKVEVPATGRTLVLAFVKTCAVLAAVHGLYILHEVDLTTAHKEAEWEFEPLAWRVWLVVFYFGCLSLTVWLLEGSYGGSDHHAARAQSPDVRARRSELDDNIAQMGAVHGLELPRRQVLRHRGT
What are the official names of this protein?
I-leader protein.
What are the subcellular locations of this protein?
Host cytoplasm, host perinuclear region. Note=Might be loosely associated with the nuclear membrane.
Protein: RLMN_PARPJ
Sequence: MTSSPTVNLLDLDAQGLVAYCDSLGEKPFRAKQLQRWIHQYNAADFDGMTDLAKSLREKLKGRATISMPGIVSDNISTDGTRKWLIDVGNSNAVETVYIPEETRGTLCVSSQAGCAVNCRFCSTGKQGFSRNLTTAEIIGQLRMAEFALRASRGIDGGRATGGDGKGERVVTNVVMMGMGEPLLNYDAVVPAMRLMLDDNAYGLSRRRVTLSTSGVVPMMDRLGADLPVALAVSLHAPSDPLRDMLVPLNKKYPLRELMAACQRYLKVAPRDFITFEYCMLDGVNDSEAQARELLALTRDVPCKFNLIPFNPFPESGLIRSKPEQIKRFAQVLMDAGVVTTVRKTRGDDIDAACGQLAGAVKDRTRLAERTGKAAKVIEVRAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.