PharMolix/UniProtQA huggingface dataset:
Protein: RBL_RHOPT
Sequence: MNEAVTIRGKERYKSGVMEYKKMGYWEPDYEPKDTDVIALFRVTPQDGVDPIEAAAAVAGESSTATWTVVWTDRLTAAEKYRAKCYRVDPVPNSPGQYFAYIAYDLDLFEPGSISNLTASIIGNVFGFKPLKALRLEDMRLPIAYVKTFQGPATGIVVERERMDKFGRPLLGATVKPKLGLSGRNYGRVVYEALKGGLDFTKDDENINSQPFMHWRERFQYCMEAVNKAQAQTGEIKGTYLNVTAATMEDMYERAEYAKELGSIIVMIDLVIGYTAIQSMAKWARKNDMILHLHRAGHSTYTRQRNHGVSFRVIAKWMRLAGVDHIHAGTVVGKLEGDPATTKGYYDICREDFNPMTLENGLFFDQNWASLNKLMPVASGGIHAGQMHQLLHLLGEDVVLQFGGGTIGHPMGIAAGATANRVALEAMILARNEGRDYLHEGPEILAKAAQTCTPLKAALDTWKNVTFNYESTDTPDYAPTPSVSV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: MUTS2_GEOSW
Sequence: MHTRVLHVLEFDKVKEQLLEHVSSSLGKEKVEKLFPSSHFAEVTNWQEETDEAVAALRLRGHVPLGGIFDIRASLKRAKIGGTLSPHELLDIASTISASRQLKQFIESLHEEKEEFPHLAGYAEKLAALPEVQQAIERCIDDHGEVMDHASERLRSIRQQLRTTEARVREKLENIIRSQSAQKMLSDAIITIRNDRYVIPVKQEYRGVYGGIVHDQSASGATLFIEPQAVVELNNQLQEARVKEKREIERILTELTSIVAEHAEALLENVDILAQLDFIFAKAKYANKLKATKPVMNDRGYIRLLQARHPLIDQDVVVPNDIELGKDYTTIVITGPNTGGKTVTLKTIGLLTLMAQAGLFIPALDGSELAVFRSVYADIGDEQSIEQSLSTFSSHMVNIVDILRNVDHESLVLFDELGAGTDPQEGAALAIAILDEVHGRGARTVATTHYPELKAYGYNRDGVINASVEFDTETLRPTYKLLIGIPGRSNAFEISKRLGLDERIIERAKSHISAESNKVENMIASLEQSKKRAEEEEKKAKEARMEAEKLRSDWEQKWEELHEKRDEIIEEAKRKAADIVRASQQEAERIIRELRRMQKEKQAEIKEHELIEAKKRLEEAIPTLEKKKKERKKQTQHAFQPGDEVKVTSLNQKGYLVEKVSDDEWQVQLGILKMKINERDLEYIGSAPKTETKPLATVKGKDYHVGLELDLRGERYEDAIVRLEKYIDDALLAGYPRVSIIHGKGTGALRKGVQEFLKKHRSVKNFHFGEANEGGTGVTIVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: RBFA_PROMH
Sequence: MARDFSRAQRVSQEMQKEIAIILQREVKDPRIGMATVSGVEISRDLAYAKVFVTFLNLSAGEESDEEMVENGLKALNEAAGFIRSLLGKAMRLRVVPELTFAYDNSLVEGMRMSNLVSNVVKDDEKRRHKEEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHH_PLAOC
Sequence: MTVPATRKDLMIVNMGPHHPSMHGVLRLIVTLDGEDVIDCEPVLGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNAPEQLGNIQVPKRASYIRAIMLELSRIASHLLWLGPFMADIGAQTPFFYIFRERELIYDLFEAATGMRMMHNYFRIGGVAADLPHGWIDKCLDFCDYFLTGIAEYQKLITRNPIFLERVEGVGIIGGEEAINWGLSGPMLRASGIQWDLRKVDHYGCYDEFDWEVQWQKEGDSLARYLVRISEMTESVKIIQQALEGIPGGPYENLEVRRFDRARDSEWNDFEYRFISKKPSPTFELSKQELYVRVEAPKGELGIFLIGDQSVFPWRWKIRPPGFINLQILPQLVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: AROC_ALKMQ
Sequence: MFRLLTAGESHGKSLVGVIEGFPANVKIDIEEINRDLGRRQRGYGRGGRMKIEKDRVEILSGVRGGKTLGSPISFLIENKDYANWEPYMNPEAVDGEEKRVTQPRPGHGDLTGTLKYGFDDIRNVLERSSARETAVRVAIGSLAKQLMREFHIEVYSHVTAIGSVSLGEPVENIEKIKRAEDSEVRCLDPEVEKAMIEEIKRAKEEGDSLGGIFEIHVTGVPRGLGSYVQWDHKLDAKLAHALMSIQAIKGVEVGCGFDQAQKKGSQVHDEIFFSQEKDYYRKTNYAGGIEGGMSNGENIHLRCAMKPIPTLYKPLRTVDIETKEAVLATVERSDSCAVPAASIVGEMVAITVIAQEFLKKFGSDSLEEIRKTWKSYTSI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: FIMA1_SALTY
Sequence: MKHKLMTSTIASLMFVAGAAVAADPTPVSVSGGTIHFEGKLVNAACAVSTKSADQTVTLGQYRTASFTAIGNTTAQVPFSIVLNDCDPKVAANAAVAFSGQADNTNPNLLAVSSADNSTTATGVGIEILDNTSSPLKPDGATFSAKQSLVEGTNTLRFTARYKATAAATTPGQANADATFIMKYE
What is the function of this protein?
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0. 5-1. 5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.
What are the official names of this protein?
Type-1 fimbrial protein, A chain, Type-1A pilin.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: UPPP_BRUMB
Sequence: MDFFNLLEAAFLGLIEGLTEFIPVSSTGHLLLIGHFLGFESTGKTFEVLIQLGAILAILSVYSAKLARIATDFPRDARTRRFVLGVLVAFLPAAVIGALAHGFIKGVLFETPMLVCIMLIVGGFILLWVDQLNLRPRYHNVMDYPLPICLAIGFIQCLAMIPGVSRSGSTIVGSLLLGADKRSAAEFSFFLAMPTMAGAFAYDLFKSRNILSFNDGALIVVGFIMAFISGVFVVRHLLDYVSRHGFALFGWWRLIVGSAGMAALIIWG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACTZ_MOUSE
Sequence: MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF
What is the function of this protein?
Part of the ACTR1A/ACTB filament around which the dynactin complex is built.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules.
What are the official names of this protein?
Alpha-centractin, Centractin, ARP1, Actin-RPV, Centrosome-associated actin homolog.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cell cortex.
Protein: NUOCD_ECO8A
Sequence: MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1509_FERNB
Sequence: MVNMFKHIKKSSNNSESWNKKEWQIAEELAVKYLKEKGYKILEKNFKTPYGEIDIIANKKDIIIFVEVKSGKGIRIQPSERVDDKKYLKIVKSAEFYLEFYLKNKNYKISQIDVIEIINGNIKHYENVGWDFT
What are the official names of this protein?
UPF0102 protein Fnod_1509.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: HCRB_THAAR
Sequence: MNILTDFRTHRPATLADAVNALAAEATLPLGAGTDLLPNLRRGLGHPAALVDLTGIDGLATISTLADGSLRIGAGATLEAIAEHDAIRTTWPALAQAAESVAGPTHRAAATLGGNLCQDTRCTFYNQSEWWRSGNGYCLKYKGDKCHVIVKSDRCYATYHGDVAPALMVLDARAEIVGPAGKRTVPVAQLFRESGAEHLTLEKGELLAAIEVPPTGAWSAAYSKVRIRDAVDFPLAGVAAALQRDGDRIAGLRVAITGSNSAPLMVPVDALLGGNWDDAAAETLAQLVRKTSNVLRTTITGVKYRRRVLLAISRKVVDQLWEAR
What is the function of this protein?
Component of a complex that catalyzes the reductive dehydroxylation of 4-hydroxybenzoyl-CoA to benzoyl-CoA.  Reaction is not reversible.  Is a key enzyme in the anaerobic degradation of phenolic compounds.
What are the official names of this protein?
4-hydroxybenzoyl-CoA reductase subunit beta, 4-HBCR subunit beta.
Protein: YKGJ_ECO57
Sequence: MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLTEQISPFHRCMSGTNQKNPRCIALAGTPGKNACCTIYKNRSSTCREFAMSGENGVVNEACNRARAKYGLTPL
What are the official names of this protein?
Uncharacterized protein YkgJ.
What is the protein family that this protein belongs to?
To A.calcoaceticus putative ferredoxin.
Protein: YHZ2_SCHPO
Sequence: MSDEAYAAFLETANKPVPSYSGDSSQLPSKWLRSSKNMLEDPSFKTLAGKVKDEYFVSESDEKFHPICIDNIPDEFEEIDAKTFDPHQKYKKVIHAIEQSSGSKDIHYFSYEESSTKTVYYVLAHLNDNKWFGVATVGIYT
What are the official names of this protein?
Uncharacterized protein C21B10.02.
Protein: REL2_ORYSJ
Sequence: MGCTASKVEQEDTVRRCKERRRHMKEAVASRQQLASAHADYLRSLRLTAAALSRFAQGHPSLAVSHHTAPVLLTTAAPALAPTPTPPPPSSTASSSLPPPTPLLPKHQQAPPPPPPTQSHQPPPPVAVRAPRGGPRRLKVPHILSDSSVASPARSSFRKPVVGTPSSSSAWDWENFYPPSPPDSEFFDRRKADLEEANRLRELEEEEKARGYLHPHHLKEEDEVDDDDDEREEEMHCGGWEDDDDHYASTTTSETRSEEGEMGNRSECGFAARSEYGGTAPSEYAAAPLPLPLRRRDERSEAGDSSSTVTAAAEMRMVIRHRTLAEIVAAIEEYFVKAAEAGNGVSELLEASRAQLDRNFRQLKKTVYHSNSLLSSLSSTWTSKPPLAVRYKLDTNALEMESMEGKSHGSTLERLLAWEKKLYQEVKARESVKIEHEKKLSTLQSLEYRGRDSTKLDKTKASINKLQSLIIVTSQAATTTSSAIVRVRDNELAPQLVELCFALLSMWRSMNHFHEIQNEIVQQVRGLVDNSMAESTSDLHRLATRDLEAAVSAWHSNFNRLIKYQRDYIRALYGWLKLTLFQVDSNIPQEAYTSLISRELTTFCDEWKQALDRLPDASASEAIKSFVNVVHVIYTKQAEEMKIKKRTETYSKELEKKTNSLRAIEKKYYQSYSMVGLGLPGSGRDGIESHSFDARDPLAEKKTEIAQCRRKVEDEMTRHAKAVEVTRSMTLNNIQTGLPGMFQAIAGFSGTVVEALDVVCRRAGSVR
What is the function of this protein?
Involved in the regulation of leaf shape formation (PubMed:27473144).  May function by coordinating the expression of genes associated with leaf and bulliform cell development (PubMed:27473144).
What are the official names of this protein?
Protein ROLLING AND ERECT LEAF 2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NEP_I57A2
Sequence: MDPNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVRHKLKITENSFEQITFIQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: EFTU_OSTTA
Sequence: MAREKFERTKPHVNIGTIGHVDHGKTTLTAAITMAMAARGGSAGKKYDEIDSSPEEKARGITINTAHVEYETATRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSGADGPMPQTKEHILLAKQVGVPNIVVFLNKEDQVDDEELLELVDMEIRETLSSYDFPGDEIPVIAGSALLALEALSSNPKIGDGEDKWVDKIFSLMDNVDSYIPTPARETDKTFLMAVEDVFSITGRGTVATGRVERGTVKVGASIEIIGYVDTRVATVTGLEMFQKTLEESVAGDNVGVLLRGIQKEDIERGMVLAQPGTITPHTKFEAQVYVLKKEEGGRHTPFFPGYRPQFYVRTTDVTGKIESFISDEGDEATMVMPGDRVKMVVELIQPIAIENGMRFAIREGGRTVGAGVVSSILK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, chloroplastic, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RBM33_MOUSE
Sequence: MAAALGAGGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELEDDLLGEDLLSGKKNQSDLSDEELNDDLLQSDNEEEENFSSQGVTISLNTTSGIVTSFELSDNTNDQSGEQESEYEQGDDELAYHKPEEQELYTQEYPEEGQYEGHDAELTEDQIEYGDEPEEEQLYSDEVLDIEINEPLDEFTDEEYLQAYGGQQGLQVREDCEAEDDLDEITDSQVASETHEGGMETLELQKDIKEESDEEDDDDEESGRLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYGSRRGGRRGGSLMCRGMGDQRRDNSERGRMKEHRPALLPTQPSVVAHSPRLIPPPQPQPPPPPPPPPPQQQPIRSLFQQQQLQPLLPLQHPHHPSPPQGVHMPPQIETPRMMLTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFNQPPRLPLQDQWRAPPPPQERDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATARPFIPPRQPFLPSPGQPFLPTHAQPNLQGPLHPPLPPPHQPQPQPQQPQQQPQHHQHQPPLQPPLQPPHQPPPQHQPPPQHQPQQHQHHHHLSAPPPPLMPMSQPQFRPHVQTAQPQPSSSRMQCTPHQGLRHNAASQNISKRPMQQMQPTAPRNSNLRELPIAPSHVLEMSGNRCSSTPVAQVKSIVNTSPPCRAVVSSRSSQGNTDAKAKPLSPEAQPKEEAKPEAEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQQQQQQHQPQQQQQQPQQIYGSQTSMEQEELAATPSPTNGNPLLPFPGAQCRQNVKTRLLVKNQDITTASVQPKAVNFVPPGANVQHQGQHLRPLKHLRQLPHKVLQVKPMDMEETPHSPQAARVTSLQGRPQDTKPGVKRTVMHRANSGGGGDGPHVSSKVRVIKLSGGQGGESDGFSHTEGQPQRLPQPPDMRQQPTRKVTLTKGVPQQPQHLPVGPHMYPAIPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSSSTTDVQLKSLLMSVGPIQSLQMLPQQRKAIAKFKEPAHALAFQQKFHRHMIDLSHINVALIVE
What are the official names of this protein?
RNA-binding protein 33, Proline-rich protein 8, RNA-binding motif protein 33.
Protein: KCY_MYCBO
Sequence: MSRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQMSLGYDPDGDSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSIVVEGRDIGTVVFPDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLADVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEAVR
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN6_CAEEL
Sequence: MALNAPSGSCSSKVLLHPLVIMQMSEHYSRTKVQQGPTVKKVFGAILGRQNGRQVEAINSFVLKMETEEMAEPVTFSTEHLLQRADQYLEVFPELQVIGLYCAGEDDNLTPEEKPLLSKLTNAVRNSEKAGQIDATLFLKLNSITAGTTRKLPLFAFEADVTDQEKHKPIEWILVSEESERVGVNHIAKLSTKHGKDGKSVGKKHAEAQDAAMSMLQNRVDLIVAYLEKVQDGTLQPNFEILKEANLLAQKLKTIDRYAAEFTDSFEKEEKTMTVFSLMPRLTTLLGNMQNVWNKLSAQRADLLADDGFHGKSTSRWAHPVRFKSQHLGRPQQADDDDYFDDEDLENDMSGPRRKIHAADSPAGSRRRRVPPRAMNFLGRNSGMQAATDEMELSGQEENMGSNYIPDVPRPSATAHNESDESSQAS
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo.  Mediates mei-3/katanin targeting for degradation at the meiosis to mitosis transition via deneddylation of cul-3.
What are the official names of this protein?
COP9 signalosome complex subunit 6, Signalosome subunit 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GUF1_IXOSC
Sequence: MFRTPHTLQFCSVHYKTFIDAIHALQSRISQKVLCRSCSSRVSGPAKKYDVDPSQFPQENIRNFCIVAHVDHGKSTLSDRLLEFTDTIRTSKDNQQVLDRLPVERERGITVKAQTVSMVYHRPGHESPFLLNLIDTPGHVDFSYEVLRSVAVCQGVILLVDANQGVQAQTVANFNMAFCSDLTILPVLNKVDLKNADVEGVTSQMENLFGTRREDVLKVSAKLGTGVEELIEAIIDRIPSPKGDADAKFRGFLLDSWYDRYRGVIALLMAVDGTLRLGDEIISHMTGTSYTVRDLGFLNPLETPTAMLCAGQAGYVVANMRSPKEAHVGDTLSHKSADIKPLPKLEESKPMVFAGIYPEDQSQNNELRSAIDRLLLNDPSVQVSIESNPALGQGWRLGFLGLLHMDVFCQRLDQEFDAQVVVTAPSVSYKVKVHGAKNIKKYGGEMVTVNNPLHLPDRSIIREYYEPMAFGTIITPGTYLRDVTSLCVDRRGVPKSTQDVDDNTILLQYKFPLNEIIVDFYDELKSITSGYASFDYEETGYEESSLVQMQILINGKVVEELTTIVHTTRAQRVGRSMLLKLKECIPQQLYAVALQAAVGAKVLAREDIRALKKNVLAKCYGGDITRKVKLLKRHSEKQKKLRLIGNVEVPRDAFIKVLKRT
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: NOCT_AGRFC
Sequence: MKFFNLNALAAVVTGVLLAAGPTQAKDYKSITIATEGSYAPYNFKDAGGKLIGFDIDLGNDLCKRMNIECKFVEQAWDGIIPSLTAGRYDAIMAAMGIQPAREKVIAFSRPYLLTPMTFLTTADSPLLKTQVAIENLPLDNITPEQKAELDKFTKIFEGVKFGVQAGTSHEAFMKQMMPSVQISTYDTIDNVVMDLKAGRIDASLASVSFLKPLTDKPDNKDLKMFGPRMTGGLFGKGVGVGIRKEDADLKALFDKAIDAAIADGTVQKLSQQWFGYDASPKQ
What is the function of this protein?
Component of the nopaline active transport system probably consisting of four subunits: Q, M, P and T.  This system is also capable of transporting octopine provided that catabolic functions are induced with nopaline.
What are the official names of this protein?
Nopaline-binding periplasmic protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KV139_HUMAN
Sequence: MDMRVPAQLLGLLLLWLRGARCDIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 1-39, Ig kappa chain V-I region DEE, Ig kappa chain V-I region Hau, Ig kappa chain V-I region Mev, Ig kappa chain V-I region OU, Ig kappa chain V-I region Walker.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: HFLD_YERPG
Sequence: MAKNYYDITLALAGICQSARLVQQLAHEGQCDNDALNTVLRGLLQTNPSSTLAVYGDTEQVLKMGLETLQSVLNANRQGEAAELTRYTLSLMVLERKLSASKSAMNTLGERISQLDRQLAHFDLESETMMSSLASIYVDVVSPLGPRIQVTGSPAILQSPLVQAKVRATLLAGIRSAVLWQQVGGSRLQLMFSRNRLFKQAQSILAHT
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.