PharMolix/UniProtQA huggingface dataset:
Protein: BOT2_BOTFU
Sequence: MAIPALEPQLHDADTSSNNMSSNSTDSGYDTNSTTPLEKSEKPNTQELKQQQLDPKRPPFVRVPDLFGSIMSTKPVVNPNYFAAKARGDRWIARVMNFNKAVAARNSKVDLCFLASMWAPDAPEDRLVMMLDWNHWVFLFDDQFDEGHLKEDPAAAAEEVKQTIAIMGGNAPRYTAESNPIRYVFQQCWDRLKAVSSQEMQQRWIDQHKRYFDQLLVQVDQQVGGENFTRDVEAYMDLRRGTIGVYPAISLSEYGAGVNVPQHVYDHPSLQECMKVSADLVTLVNDVLSYRKDLELGVDHNLMSLLMQRDNLSAQQAVDVIGDMVNECYRRWYLALAELPSYGEKIDYNVMKFVEICRAVAQGNLYWSFQTGRYLGPEGHEVHETGIMYLPPAANLVVA
What is the function of this protein?
Presilphiperfolan-8-beta-ol synthase; part of the gene cluster that mediates the biosynthesis of botrydial (PubMed:14651630, PubMed:19035644, PubMed:19476353).  Botrydial is necessary for colonization of plant tissue by the T4 strain (PubMed:19035644).  It is a strain-dependent virulence factor since highly aggressive strains like SAS56 or B05 still retain substantial virulence when botrydial synthesis is impaired, since they produce also botcinic acid (PubMed:15986930).  The first step of botrydial biosynthesis is performed by the sesquiterpene synthase BOT2 which catalyzes the cyclization of farnesyl diphosphate (FPP) to presilphiperfolan-8-beta-ol (PSP) (PubMed:19035644, PubMed:19476353).  The cytochrome P450 monooxygenase BOT4 then catalyzes the hydroxylation at C-4 to give a probotryane intermediate (PubMed:27529428, PubMed:28617493).  Acetylation of the hydroxyl at C-4 is carried out by the acetyltransferase BOT5, followed by the combined action of the P450 monooxygenases BOT3 and BOT1, to yield finally the glycol, via the regio- and stereospecific hydroxylations at C-10 and C-15 of the probotryane intermediates, respectively (PubMed:15986930, PubMed:27529428).  The cleavage of the C10-C15 bond of probotryane skeleton is an intriguing and chemically important reaction, which could be mediated by some of the monooxygenases or by a combination of them (PubMed:27529428).  It is possible that either BOT3 or BOT1 would oxidize either the 10- or the 15-hydroxy group to the hydroperoxide derivative, which would then undergo heterolytic fragmentation to give the dialdehyde botrydial (PubMed:27529428).  Finally, the dehydrogenase BOT7 might be involved in the conversion of botrydial to dihydrobotrydial (PubMed:27721016).
What are the official names of this protein?
Presilphiperfolan-8-beta-ol synthase, PSPS, Botrydial synthesis protein 2, Calcineurin-dependent protein 15, Sesquiterpene cyclase BOT2, Sesquiterpene synthase BOT2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: VTI1B_MOUSE
Sequence: MAASAASSEHFEKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDENQQEANETLAEMEEELRYAPLTFRNPMMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIILLELAILVGLVYYKFFRHH
What is the function of this protein?
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane.  These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers.
What are the official names of this protein?
Vesicle transport through interaction with t-SNAREs homolog 1B, Vesicle transport v-SNARE protein Vti1-like 1, Vti1-rp1.
What is the protein family that this protein belongs to?
Belongs to the VTI1 family.
What are the subcellular locations of this protein?
Early endosome membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane. Cytoplasmic granule. Recycling endosome membrane; Single-pass type IV membrane protein.
Protein: AAMP_PONAB
Sequence: MESESESGAAADTPPLETLSFHGDEEIIEVVELDPGPPDPDDLAQEMEDVDFEEEEEEEGNEEGWVLEPQEGVVGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVATNQDGSLILTGSVDCQAKLVSATTGKVVGVFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSGDHKAKVFCVQRPDR
What is the function of this protein?
Plays a role in angiogenesis and cell migration.  In smooth muscle cell migration, may act through the RhoA pathway (By similarity).
What are the official names of this protein?
Angio-associated migratory cell protein.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm.
Protein: CRTI_NEUCR
Sequence: MAETQRPRSAIIVGAGAGGIAVAARLAKAGVDVTVLEKNDFTGGRCSLIHTKAGYRFDQGPSLLLLPGLFRETFEDLGTTLEQEDVELLQCFPNYNIWFSDGKRFSPTTDNATMKVEIEKWEGPDGFRRYLSWLAEGHQHYETSLRHVLHRNFKSILELADPRLVVTLLMALHPFESIWHRAGRYFKTDRMQRVFTFATMYMGMSPFDAPATYSLLQYSELAEGIWYPRGGFHKVLDALVKIGERMGVKYRLNTGVSQVLTDGGKNGKKPKATGVQLENGEVLNADLVVVNADLVYTYNNLLPKEIGGIKKYANKLNNRKASCSSISFYWSLSGMAKELETHNIFLAEEYKESFDAIFERQALPDDPSFYIHVPSRVDPSAAPPDRDAVIALVPVGHLLQNGQPELDWPTLVSKARAGVLATIQARTGLSLSPLITEEIVNTPYTWETKFNLSKGAILGLAHDFFNVLAFRPRTKAQGMDNAYFVGASTHPGTGVPIVLAGAKITAEQILEETFPKNTKVPWTTNEERNSERMRKEMDEKITEEGIIMRSNSSKPGRRGSDAFEGAMEVVNLLSQRAFPLLVALMGVLYFLLFVR
What is the function of this protein?
Phytoene desaturase involved in the carotenoid biosynthesis pathway (PubMed:2144609, PubMed:11017770, PubMed:18812228).  Converts phytoene into 3,4-didehydrolycopene via the intermediates phytofluene, zeta-carotene, neurosporene and lycopene, by introducing up to five double bonds into phytoene (PubMed:11017770, PubMed:18812228).  Is also able to desaturate 1-hydroxyneurosporene into 1-hydroxylycopene and 1-hydroxylycopene into 1-hydroxy-3,4-didehydrolycopene (PubMed:11017770).  Gamma-carotene and 1,19-dihydroxylycopene are not accepted as substrates (PubMed:11017770).  Neurosporaxanthin is synthesized from geranyl-geranyl pyrophosphate (GGPP) through several enzymatic activities.  Phytoene synthase activity performed by the bifunctional enzyme al-2 first produces phytoene from geranyl-geranyl pyrophosphate (GGPP).  The phytoene dehydrogenase al-1 then introduces 5 desaturations to lead to 3,4-didehydrolycopene via the intermediates phytofluene, zeta-carotene, neurosporene and lycopene.  Al-2 cyclase activity then converts 3,4-didehydrolycopene into torulene.  Al-2 can also convet lycopene into gamma-carotene which in turn is converted to beta-carotene by an additional al-2 cyclization reaction.  Torulene is the substrate of the dioxidase cao-2 that breaks the molecule, removing five carbon atoms to yield beta-apo-4'-carotenal, whereas the aldehyde dehydrogenase ylo-1 mediates the last step by converting beta-apo-4'-carotenal into neurosporaxanthin (Probable).
What are the official names of this protein?
Phytoene desaturase, Albino-1 protein, Phytoene desaturase (3,4-didehydrolycopene-forming).
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NUOI_BAUCH
Sequence: MTLKQLVTGCYTILRSIWMIGMQAFNKRETQMYPDIPIYQTSRFRGRIVLTCDPDGYERCVACNLCAVACPVDCISLQKTESKEGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMAEFKRQDLVYEKEDLLIRGPGKYPEYNFYRMAGIACNDKLKGHAENETRPINVKDLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: H2B8_ARATH
Sequence: MAPKAAEKKPAGKKPAEKAPAEKLPKAEKKITKEGGSEKKKKKSKKNIETYKIYIFKVLKQVHPDIGISGKAMGIMNSFINDIFEKLAQESSRLARYNKKPTITSREIQTAVRLVLPGELSKHAVSEGTKAVTKFTSS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.8, HTB6.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RF2_STAAS
Sequence: MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1056_STRS7
Sequence: MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKSYAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR
What are the official names of this protein?
UPF0223 protein SZO_10560.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: MAN3_ARATH
Sequence: MKCLCFVVLLAILIAQNSSDLGVKSASSDGFVSRKGVQFILNGKPFYANGFNAYWLAYEATDSTTRFKITYVFQNATIHDLTIVRTWGFRDGGYRALQIAPGVYDEKTFQGLDFAIAEAKRLGIKMIITFVNNYSDFGGRKQYVDWAKNTGQNVSSDDDFYTNPLVKQYYKNHVKTMVNRVNTFTKVEYKDEPTIMGWELMNEPQCRADPSGKTLTAWMNEMALYVKSVDSKHLLSTGLEGFYGDSSPQRKTSLNPVAANVLGTDFIANHKLDAIDFASIHSYPDLWFPNLDEKSRLNLLRKWLECHLEDAQNILKKPLILGEFGKPTNTPGYTQAQRDAVFNATFDTIYESAEKGGPAAGALFWHVISDGMNNFKDPLSIVLSENSTTVNIITEESRKLGLIRGKGKLSKTKI
What are the official names of this protein?
Mannan endo-1,4-beta-mannosidase 3, Beta-mannanase 3, Endo-beta-1,4-mannanase 3, AtMAN3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOI_MYCSJ
Sequence: MPKLWDAVAGFAVTFGTLFKKPITEEYPEKPGPVAPRYHGRHQLNRYPDGLEKCIGCELCAWACPADAIYVEGDDNTADERYSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTNDYEMADDNRADLIWGKDKLLAPLQDGMLAPPHPMAPGATDDDYYLGRIGPVTEDVR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NUOH_BORA1
Sequence: MEWLNVLESQGQALLGPTAWLVVWTIIKIVIIAVPIILCVAYLTYWERKMIGWMHVRLGPNRVGFKGLLQPFADVFKLLTKEVVVPSQANKILFIVAPVVTLMPALAAWAVVPFGPEAVLANVNAGLLYVMAITSIGVYGVIVAGWASNSKYAFLGALRASAQMVSYELAISFVLVTVLLVSGSLNMNEIVLGQGRGWFAERGLTFLSWNWLPLLPLFVIYVISAVAETNRHPFDVVEGESEIVAGHMVEYSGMAFALFFLGEYANMILLSAMASIMFLGGWMSPIDIAPLNWIPGWIWLGIKTFFVVSLFIWFRASFPRYRYDQIMRLGWKIFIPLTGVWLVVVAIWMQTPWNIWR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MYBPP_MOUSE
Sequence: MMKKITERQSPLKLLEKKRAKAPEQPTPPIQEEPEPVSNVLQGDDILALAIKKEDLRKQHVPQFEETGEKPVVTQKFIIRKLKPKDSSKRVYHLVAHPATPDAATKPLDYSGPHDSFLSSGQILPHQILGSLQDFKRIAVARGNTQLAKLIHIQPCLMTLISAKEEPKPKPPKEEERPSPWAPPPQHNFLKNWRRHIALRKKQQEALSKHLKKPASELLMHTGESYRKIQEEREVIDRALPTQHDGKATSWFWSPLEYLGDEMTGLLMTKKKTQRGLVEPITHIRKPLSIQVETGLPAQKDAWYRYTWDRSLFLIYRRKELQSIMAELDFSQQDIDGLEVVGHGKPFSSVTVEEHLPPEKIQKSSSEDTVFLDSLTNLSDMVPMPILGPSLLFCGKPACWVRGSNPEDKKNIGIGVRLTFETLEGERTSSELTVVNNGTVAIWYNWRRRPHQDFFQDLKQNKTQRFYFNNREGVILPGETKHFTFFFKSLNAGIFRESWEFGTHPTLLGGAVLQVTLHAISLTQDIFMDERKLLETKLAAHEAITIAQSVLQDLLRGISTPERTPSPVDAYLTEEDLFNYRNPRLHYQHQVVQNLHQLWQQYRKAKATQKETPSLRTPVPLLLVEKASGSISPRNLVSEYSQLSPHQEMDTARKTRDFFLSLKSSIGKKSVARKSIMEELLVEEGPDRETTQRPWALKSISPPKWNLCLEDFRQAVMTFPEELQREDALIQLNKAAMELCQEQKPLQSDLLYQMCLQLWRDVIDSLVSQSLWLRNLLGLPEKETVYLDLPDEQGQKSPPVTESKVTSGKAGKEDRRGGAQEKKQLGTKDKDDKRGSKTPGKEDRPNSKKLKPKDDKKVVKSASRDRLLSEDPPPDSTAPSQEPIDPLVMEKYTQRLHAEVYALLDNLVTDVMVLADELSSTKNVEESLRFCS
What is the function of this protein?
May play a role in spermatogenesis.  May be involved in synaptic processes (By similarity).
What are the official names of this protein?
MYCBP-associated protein, AMAM-1, AMY-1-binding protein 1, AMAP-1.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=Colocalizes with MYCBP in the cytoplasm.
Protein: CWP06_SOLLC
Sequence: SNAVAVLNXXEXM
What are the official names of this protein?
21 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RING4_ARATH
Sequence: MSSSSSTTTNTTTESDSSSLPTHIGRSNSDGIIDTTPFLPPTVTRTISVDEESNPIHRSARRQGLREAARFLRHAGSRRMMREPSMLVRETAAEQLEERQSDWAYSKPVVFLDILWNLAFVAIGVAVLILSRDEKPNMPLRVWVVGYGIQCWLHMACVCVEYRRRRRRRHPEDGGGSGLTNSSSQQYVSLAQLEDRGETSNPAKHLESANTMFSFIWWIIGFYWVSAGGQTLSSDSPQLYWLCIIFLGFDVFFVVFCVALACVIGLAVCCCLPCIIAILYAVADQEGASKNDIDQMPKFRFTKTGNVEKLSGKARGIMTECGTDSPIERSLSPEDAECCICLCEYEDGVELRELPCNHHFHCTCIDKWLHINSRCPLCKFNILKNANNEV
What is the function of this protein?
Mediates E2-dependent protein ubiquitination in vitro.
What are the official names of this protein?
E3 ubiquitin-protein ligase At4g11680, RING finger protein At4g11680, RING-type E3 ubiquitin transferase At4g11680.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYA_GEOSL
Sequence: MTGKEIRARFLKFFADRGHAVVPSSPLIPHNDPTLLFANAGMNQFKDCFLGLEKRDYVRACSSQKCVRAGGKHNDLENVGRTARHHTFFEMLGNFSFGDYFKKEAIAFAWEFLTKDLGLDKDRLYVTVYTDDDEAADIWHLQEGVPRERIYRFGEKDNFWAMGDTGPCGPCSEIFWDNGPEVGCGSPDCAVGCDCDRYMEIWNNVFMQFNRSADGVLTPLPKPSVDTGMGLERISTVMQGVKSNYDTDLFQGIIGHVEKLSGKRYRHSEKDDVSMRVMADHVRATTFLICDGVLPSNEGRGYVLRRIMRRAARHAKMLGFAEPVICRMVEAVNAMMGDAYPELLEREEYIRKVIRAEEERFAETLDRGLAILNEAVADLKNEGRTVIPGETLFRLYDTFGFPTDLTADIVRSEGFTIDEDGFEACMERQREQAREHWKGSGEEGIAEVHKTLHSRGVRSRFTGYEARTAYSPVTVLLKGGAEVAEATAGDRVEIITDATPFYGESGGQVGDTGTISTGSAHVEVTETLRPFPDLIVHRGTVVEGTIRQGDACDLKVAPGRDATARNHTATHLLQSALRQVLGDHVKQSGSLVGPDRLRFDFTHFAAMTPEEIRRVEEIVNSCIMANDDVHAREMALDEAMEIGATALFGEKYGDTVRVVRVGEVSMELCGGTHVHAAGDIGFFKILSEAGIAAGVRRIEALTGMGALRHVQQLEDERKEIAALIKAEGGDNVERLQRLLTRQKDMQREIETLESRLNAARSADLLADVREVNGVKVLATLAEVDDPKKLRELADTLKDRLGSGVVALGCVKEGKANLLVAVTKDLTGRVKAGDLIRQLSPIIGGSGGGKPELAQAGGTLPDKLGEALGKVCELVP
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_AGRFC
Sequence: MRILLTNDDGVHAEGLAVLERIARTLSDDVWIVAPETDQSGLAHSLTLSEPLRLRKVSDKHFALRGTPTDCVIMGIREVLPEKPDLVLSGVNAGANMADDVTYSGTIAGAIEGTLQGVRSFALSQAFSHGEGRVVPWEVAETYAPDLLRKLMNVDLPDGTFLNLNFPNCAPKDMQGVSVTGQGKLDFGLTVEERQDGRGLPYYWLRFGERLGTFREGTDIHALKHGKISVTPLKLDLTDYTVKDRVAQALGFGVAD
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUTC_BACVZ
Sequence: MMMKGTVTHQESFLNRIAESLGRERRKSGVSLPEWKYQPQYQTHAGCTEDDLVTMLKDHCVNIHTELIETDAAGLYDALRTQVNRFEGGPVIIPKDSRFETYGLQTLMTEEWPDEGIPVWEWDAEQGAKNIEKAEQANVGITFSEITLAESATVVLYASEHAGRSVSLLPTTYIAIIPKSSIVPRMTQASDILKQQIRDGVTVPSCINYITGPSNSADIEMDLVVGVHGPVKAAYILVNDR
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein C.
What is the protein family that this protein belongs to?
Belongs to the LutC/YkgG family.
Protein: TRUB_THEGJ
Sequence: MARDEVRRILPADIKREVLIKDEKAETNPKWGFPPERRPMEMHMQFGIINLDKPPGPTSHEVVAWIKKLFNLSKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDIPEDKILAVMKEFQGEIIQRPPLRSAVKRRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIRDSAVAAVTHGADLAVPGIVKLHKGIKKGDLVAIMTLKDELVALGKAMMTSGEMLQRSKGIAVDVDKVFMPRDWYPRMW
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: DLX5A_DANRE
Sequence: MTGVFDRRIPSIKPADFQNPFQLSTMHHPSQESPTLPESTATDSGYYSPAGGVHHGYCSPNSGTYGKPLNAYQYQYHGVNGSSGNYSAKSYPDYGSYSTAYHQYAGTYNRVQSQPSPQEKETAEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQNTQYLALPERAELAASLGLTQTQVKIWFQNKRSKLKKIMKNGELPPEHSPSSSDPMACNSPQSPAVWDSQGPQRPHHQPQNINTAASTFLEMRELFVVFLYRGDEFFTLQAPGTLHSLALGSGTLY
What are the official names of this protein?
Homeobox protein Dlx5a, DLX-4, Distal-less homeobox protein 5a.
What is the protein family that this protein belongs to?
Belongs to the distal-less homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSRQ_BRUMB
Sequence: MAAATGTRKKKTPRPGQWKLWLLYTAGFVPAVWTFYLGATGQLGADPVKTFEHLLGLWALRFLILTLLVTPMRDLTGITLLRYRRALGLLAFYYALMHFTTYMVLDQGLNLSAIITDIVRRPFITIGMISLALLVPLALTSNNWSIRKLGRRWSSLHKLVYIAIAGSAVHFLMSVKSWPAEPVIYAAIVAALLLWRLARPYLRTRKPALRPRGEAIALRK
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PALF_CANGA
Sequence: MAFIKLLRKTKDEPSRLAKAVRHLQVTLDDPHATYRPRDVLFGQVLLDLKQNVANVRVRLTFIGEVKSKYGTAHKRGGCFMEKSTVLYGDDGDLDTDEMEPTVNGLTKGVHKFPFSIRVPSGKKIHSSIKFERGSVSYHLMAVFESVVEPEGVSAKVRTKVNILVPIDVYRYSDVVVKTILLNSNAKSKSHKINSNDHNGHLNGDVTTLTTSDGSSEGTKKTISESQIINNLSQRQVLQKSKSEGSKSESIQASTGQINQLPETSSQVSYNAVLTNGMNRDADNQTVKIDVRLPHSGFVQGEYIPLTINVSHYREYYHPAGVIATLVRVCKVASGRKEDTKEIYRKDICQSISPLLIESNKLENTISTYLKVPNDIIASMTSLPEHFTFQYFVEVVINLSRKLEIYSHSQKPLSYILEKQKTKKPLTIPRDLKELNLPASVNENGAWEVPRPSLNNEKSNGGIDSSRNDFQSKFGSAFNKSTLFGLKNIDEIHVAEQTIIFDDMVDVERLKRMRNVAGLSIETIIGNKRSSPAIDLAKLEISKLSQGKVMKSNGTSKNTSSSGSIESNSIVRYRYISFEQDTQSSTDSYDEDITKMGNQLNEWLSPANAYEEYYPVPEYSANENVFASEDKQELEYKRLHELESDPPQF
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palF/RIM8.
What is the protein family that this protein belongs to?
Belongs to the arrestin family. PalF/RIM8 subfamily.
Protein: EFP_BEUC1
Sequence: MASTNDLKNGLVLDLDGQLWTVVEFQHVKPGKGPAFVRTKLKHVLSGKTVDKTFNAGIKVDTATVDKRDMQYLYKDGDDFVFMDSSDYEQFHVGPQIVGDAANFMLENTEVIVALHEGNPLYVELPTSVVLEITYTEPGLQGDRSSAGTKAATVETGYQIQVPLFLEIGTKVKVDTRSGDYLGRVN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.