PharMolix/UniProtQA huggingface dataset:
Protein: ISPH_PSYIN
Sequence: MEIILANPRGFCAGVHRAISIVDRALDIFTPPIYVRHEVVHNQYVVDDLRARGAVFVEELDEVPENSIVIFSAHGVAQSVRAEAKRRDLKIFDATCPLVTKVHMEVTRASRRGQECILIGHQGHPEVVGTMGQYDNPQGGIYLIESPEDIKKLEVKNPNSLCFSSQTTLSVDDTANIIKALREKFPKIDGPRKDDICYATQNRQDAVKALAERSDLVLVVGSTNSSNSNRLQEKASCVGVNAYLIDSEKDIKTEWLENVKVVGVTAGASAPEVLVKEVIARLKKLGGTVVTENLGVEENIIFEVPAELRIKQID
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RL19_BART1
Sequence: MNIIAQLEAEQCAKIEEKRQFPAFKPGDTVRVMVRVTEGTRTRVQAYEGVCIARSGGGLNETFTVRKISYGEGVERVFPVYSPLIEAVELVRRGKVRRAKLYYLRGLRGKAARIAEKRDYRKKGEKGVEKVETTPVSADIETQVAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL1_ECOHS
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTMGAGVAVDQAGLSASVN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MSHB_FRASN
Sequence: MTQSAETVLPPRRVLFVHAHPDDEVISTGVTMASYAARPDTHVTLVTCTLGEVGEVLVPELINLRSDLGDQLGGYRIGELDRSCAELGVTDHRFLGGAGRWRDSGMIDTPANDDPRCLWRADLDEASAALVQVVREVRPQVLVTYDENGAYGHPDHIRAHDVSVRAFADAANPDFAPEAGQPWQISKFYETATPKSFVQAGIEYFRESGGESPFGPAESADDIPLAVPDELITTEIQADEYLPAKVAAMRAHRTQMAVDGFFFALADGIGKRAWAAEHFVLTRGERGPGTEPGAHETDLFAGLPL
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: AT1B3_CAEEL
Sequence: MTNGGRNGEENKNLMNGEAKAEPETFAQFLYNKDKGTVLGRTGTSWCQITVFYIIFYIFLSAFFIGCLSIFLRTLDPKVPRFYGKGTIIGVNPGVGYQPWLKENPDSTLIKFNLQDSKSWEPYVKQLDNYLSKYKNTNETRDCGASDNNDALETDTDTFPCRFDLGLFEKANCGAKDQYGYKSGKPCVAVSLNRLIGWRPVNYDDGSVPEEIKGRYKPGSITINCEGATSFDKEHLGKVKYIPETGIDGRYYPYVFVPSYQQPIAMVKFDTIPRNKLVIVECRAYASNIEHDISTRLGMVYFELFVEDKKPVAAPAA
What is the function of this protein?
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.  The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity).  Implicated in genomic response to various soil bacteria that affects fitness, lifespan and brood size.
What are the official names of this protein?
Probable sodium/potassium-transporting ATPase subunit beta-3, Sodium/potassium-dependent ATPase subunit beta-3.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: PURA1_METAC
Sequence: MSVTVIVGAQCGDEGKGKMVDLIAQDYDLVIRFQGGDNAGHTVVNQYGTFKMHLIPCGIFNQNAISLVGTGMVVNPDELQKEMKQITSAGMSVDNLKISTRANILMPYHRDLDELNEQSGGMSIGTTKRGIGPAYAGRATRTNIRFGDLAHQDYLKSHFEKVLPAINHQLSFFGAAQYTVDQLCEYCSNWYKLYNEHIVDAFTLIHNMMKENKRILFEGQLGVMKDIDLGIYPFVTSSNPIAAYAAVSSGIPARSITSVIGVAKAFSSQVGDGPFPTEVLDNCIVSLRGTGKNIDDEFGARTGRPRRLGWLDIPVLRYAHTINGFDTLAICKLDKMDSLPEIKICTSYRYQDQILSVFPDTEILGQVKAEYETLPGWECTTRGVNSFDDLPENAKSYIKRIEELVGVPVKYIGVGPARSDVIIR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase 1, AMPSase 1, AdSS 1, IMP--aspartate ligase 1.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_YERPB
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAEAIVYTALETLAQRSGKDFLEAFEVALDNVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVDAARKRGDKSMALRLANELSDAAENKGSAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL5_SHEFN
Sequence: MAKLHDKYQETVVAELAKKFGYSSVMQVPRIEKITLNMGVGEAVADKKVMEHALRDMTAIAGQKPIVTVARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSAKAFDGRGNYAMGVREQIIFPEIDYDKIDKIRGMDIVITTTAKNDEEGRALLDAFNFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PLSX_LISW6
Sequence: MKIAVDAMGGDHAPKEIVLGVMKAVAQYKDIEILLFGDETKINEYLTDKTRVKIIHTDEKIESDDEPVRAVKRKKKASMVLAAQAVKDGEADACISAGNTGALMSTGLFVIGRIKGIDRPALAPTLPTVTGKGFVMLDLGANAEAKPEHLLQFGLMGSVYAEKVRKIDRPRVALLNIGTEETKGNDLTKKSFELMKNQDAYEFIGNIEARDLLMDVADVVVTDGFTGNMVLKSIEGTGAAFLSMLKMSLLNGFKNKVAASFLKKDLMELKAKMDYSEYGGACLFGVQAPVVKAHGSSNANGIFTTIRQVREMVEKQVVETIKAEVDKVKVGGTEAND
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RBSD_BACLD
Sequence: MKKHGILNSHIAKLLADLGHTDTIVIADAGLPVPPGVPKIDLALTLGTPGFREVTKLIADEMVVEKVTAAQEIESVNPGQAAFLKAEFSNQKIDYIPHEAFKKATSQAKAVIRTGEATPYANCILHAGVIF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GACG_DICDI
Sequence: MASIFLNKKTIETNNFIFNDNRPKNIKIVDKIKSSTVEFFHSIQKHIQQVKVENNNNNNNNNNNSENNKYKRSQSEENINNYIQNHFNPPQPQKKRNILFIFQNLINSGNSNNNNSSNSSCNSTPSTSPSSTPRSTNSPRSTYSPRNNNNNFTESSSDNQQFDITFNMVVEKERVILTVKVPEVGLTKKILFDKVETIKDAILLVIEKLPPGCLDASEYNLFLPQKNQWCKIDSRFSKYQFKENQEIEFKKDSRGGVSHMLSNVGNLLTRPYRTIYIKLPEIVTVGTLPPLQINGQIGDLPSLNNSLNNSLNNISSSSSGGTGGGSGTTAAATGSSLSNSNSNSNLQNSQSANNSPIIHRRRTSSFSYDPNIHHSSLTHSNSNSNLISTNTSSIGNSAPSPTTLGSKPFSIPKLNLTENNLNNSSSTSSSPRNNGNEVIQSSSSTSSPRVNAPPPLEHKKSFLNIIGISPRGTNRERSSSTNSLNNSTSSLKSSNNNILQQQQQQQQHYDSAPTTPRNFGTFVRTQQLQNQQQQLQQQESIEAFDFEDDSTLGEVLNKICTRYQYIEKDLLEDYSLITKDGLWFVDRNKTITELGLKHMDEVEFKRMTQKVKVVFLNKEIVLNFNPSDTLKEINYKIIVHYLPSLIKLSRSNSILSSSSSSIFLNHQSSSSSNSSSSPSQSYRSSLSLEPLVISDLENSQILSNTPTITTVGNHQILNLQQQQNKQRSYSDASPLSFSKDYTSEISNHQQQNIENHINRRKNSISTNPLTNSGNIANNNNNNNNNKDKDDNNNNNNNNNNNNNNNNNNNNNNNNNNIASSTDTIQSNSSTGSLGSNNNIAFSIQQNRYPIPDNLVEFKDFKLHLSGTKNQNPNINQKFDMLLDERRTLSSFNFWNNIKLHFKNSSKSLHSDSKRVAPTLPFYLQIESVEQFSVSHILELEGTLLISDILKSFNRLLLNNENIKINDPLDEYGLFFNTVNNGNREGLSYGSSIYLDPYKTLSHYPMIEPLDKLMFKRTNTIFGVDPNTIVSKIDPITGFNIPCLLLDLKQKFIELDGFSIEGIFKTNNYYDLTFTEIIKEIENGTLLTSNNPNVDAIGIACFIKRWFSKLPKKICSLLDDETLLYASTQESTAEASLDSIPQPYRSLLLWLVRFLSEVSQSAYTNKCSAKILAIVIAPNLISISPNNNNNNKENNDHHHHHHHHHNSHHHRDNNNNNSNNNSSTTPTSSSVGKYTSLEKLHQCTLFLRNLIKLKLRENGFLPISTSSISISNSHNSSSFISMTGTSETSIHSSNSPISSSISRSPSLTDIVEE
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacG, GTPase activating factor for raC protein G.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSN3_ASPFU
Sequence: MFGRNFPFFNSIGGFYPRESLDSKRPSGSGYTSKVRVRDKYHIVGFISSGTYGRVYKAIGKDGRKGEYAIKKFKPDKEGEIIQYTGLSQSAIREMALCSELDHPNVVQLAEIILEDKCIFMVFEYTEHDLLQIIHHHTQPQRHAIPAPMIKSILFQLLNGLLYLHTNWVLHRDLKPANILVTSSGAVRIGDLGLARLFYKPLNSLYSGDKVVVTIWYRAPELLMGSRHYTPAVDLWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMMKIIDIMGLPRKETWPGLVSMPEFSQLQSLAMSRGYINRQCNLEGWYQSCLKNNGYSPGSAAGTPGAEGFDLLSRLLEYDPTKRISAREALEHPYFTTGTPVTANCFAGYEGKYPHRRVTQDDNDIRSGSLPGTKRSGLPDDSLMGRAAKRLKE
What is the function of this protein?
Component of the srb8-11 complex.  The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase ssn3, Cyclin-dependent kinase 8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YGHA_ECO57
Sequence: MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINVFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
What are the official names of this protein?
Uncharacterized oxidoreductase YghA.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PYRF_STRZJ
Sequence: MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAGPEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAAREGLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEVQVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPVAAYHTIKDEWTQDWN
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: CXCR1_PONPY
Sequence: MSNITDPQMWDYDGDPNFTGMPPIDEDYRPCRLETETLNKYVVIVTYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAVSKVNGWIFGTLLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLSCWGLSMILSLPFFLFRQAYHPKNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFALCTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQLIKESCERRNDIGWALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHHVTSYTSSSVNVSSNL
What is the function of this protein?
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor.  Binding of IL-8 to the receptor causes activation of neutrophils.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, High affinity interleukin-8 receptor A, IL-8R A, IL-8 receptor type 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS7_FRAAA
Sequence: MPRKGPAPKHAVVVDPVYGSALVTALVNKVLMSGKKSVAERIVYGALEGAKNKTGNDPVVTLKRALDNVKPTLEVRSRRVGGATYQVPVEVRAGRSTTLALRWIVGYSRARREKTMTERLMNELIDASNGLGASVKRREDTHKMAESNKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: QCR10_HUMAN
Sequence: MVTRFLGPRYRELVKNWVPTAYTWGAVGAVGLVWATDWRLILDWVPYINGKFKKDN
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.  QCR10 has a role in CIII assembly and RIP1 stability.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 10, Complex III subunit 10, Complex III subunit XI, Ubiquinol-cytochrome c reductase complex 6.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCR11/QCR10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: GLMM_STREM
Sequence: MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRVFVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKYERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGSTHPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLAKNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMDYNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAIAEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RS6_STAA2
Sequence: MRTYEVMYIVRPNIEEDAKKALVERFNGILATEGAEVLEAKDWGKRRLAYEINDFKDGFYNIVRVKSDNNKATDEFQRLAKISDDIIRYMVIREDEDK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TIG_STAAT
Sequence: MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVVENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVNEIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNTTIDIPEAMVNTELDRMVSEFAQRIQQQGLDLQTYFQISGQDETQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNTLGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: NDUA8_GORGO
Sequence: MPGIVELPTLEELKVDEVKISSAVLKAAAHHYGAQCDKPNKEFMLCRWEEKDPRRCLEEGKLVNKCALDFFRQIKRHCAEPFTEYWTCIDYTGQQLFRHCRKQQAKFDECVLDKLGWVRPDLGELSKVTKVKTDRPLPENPYHSRPRPDPSPEIEGDLQPATHGSRFYFWTK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, Complex I-19kD, CI-19kD, NADH-ubiquinone oxidoreductase 19 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA8 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space. Mitochondrion.
Protein: DDL_CHLTE
Sequence: MSKQTVALFFGGKSAEHEISIISARSIAAQIDRNRYELSPLYIDRDGKWHASECSQQVLDTDIAALLRSGTPESAGKRLDELTAAAAGECFDFGSFLKNTDVAFIALHGSYGEDGKLQGCLDTFGIPYTGCGLTASALAMDKVLTKLCAMNAGIAVAEFMTITSCAYMANPLETIVEITKRFDWPLFVKPASLGSSVGISKVRNAEELAAALENACGLDSKALVEAAISGREIEVAVLGNSDPLASEPGEIIPGSDFYSYEDKYIKNEAKIVIPADLPEGVAEEVRKAALTVFKALGCEGMARVDFFVENGTNRVILNEINTIPGFTDISMYPMMMAASGIGFAELVEKLLLLALEKRSITHKI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADJ_SALDC
Sequence: MTTTSAFMLNVRLDNVAVVAIDVPGEKVNTLKAEFAAQVRAILKQIRENKALQGVVFISAKADNFIAGADINMIGHCQNAQEAETLARQGQQLMAEIQALPVPVIAAIHGACLGGGLEMALACHRRICTDDVKTVLGLPEVQLGLLPGSGGTQRLPRLVGVSTALDMILTGKQLRARQALKAGLVDDVVPQTILLEAAVELAKKERLAQRTLPVRERILAGPLGRALLFRLVRKKTAQKTQGNYPATERIIDVIETGLAQGSSSGYDAEARAFGELAMTPQSQALRAVFFASTEVKKDPGSDAPPGPLNSVGILGGGLMGGGIAWVTACKGGLPVRIKDINTQGINHALKYSWDLLETKVRRRHIKANERDKQLALISGSTDYRGFSHRDLVIEAVFEDLPLKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAANAARPEQVIGLHFFSPVEKMPLVEVIPHASTSAQTIATTVKLAKKQGKTPIVVSDKAGFYVNRILVPYINEAIRMLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVASILNDDRKGRKNGRGFYLYGEKGRKSKKQVDPAIYKLIGVQGQSRLSAQQVAERCVMLMLNEAARCFDEKVIRSARDGDIGAVFGIGFPPFLGGPFRYMDALGPGEMVATLQRLAALYGPRYAPCEQLVRMAERREHFWTNGETDQGN
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPE61_MYCTO
Sequence: MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
What are the official names of this protein?
Uncharacterized PPE family protein PPE61.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: RNH_AERS4
Sequence: MLKHIDLYTDGSCLGNPGPGGYGAVLVYGDHRKEISGGFRLTTNNRMELMAAIMGLRTLNAACQVRLTTDSQYVRQGITQWIIGWKKKGWMTSNRQPVKNVDLWKELDAEVARHQIEWLWVKGHSGHPENERCDELARDAASGKELAEDTGYQP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEG1_CAPHI
Sequence: MACGLVASNLNLKPGECLRVRGELAADAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDDGTWGAEQREVAFPFQPGSVVEVCISFNQADLTVKLPDGHEFKFPNRLNMEAINYMSADGDFKIKCVAFE
What is the function of this protein?
Lectin that binds beta-galactoside and a wide array of complex carbohydrates (PubMed:21210196).  Plays a role in regulating apoptosis, cell proliferation and cell differentiation.  Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.  Strong inducer of T-cell apoptosis.  Has hemaglutinating activity towards human erythrocytes (PubMed:21210196).
What are the official names of this protein?
Galectin-1, Gal-1, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Galaptin, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, S-Lac lectin 1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Cytoplasm. Secreted. Note=Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: APAH_HAEI8
Sequence: MATYFVGDLQGCYDELQLLLERVNFNPTQDKLYLVGDLVARGDKSLECLRFVKSLGDSAQTVLGNHDLHLIATALGIKKVKPRDRVDAIFNAPDFDELIHWLRHQPLLVHNKKLNFLMVHAGISPDWNLETAKSCAAEVEQILQNGDFHYLIENMYSEQPDRWSPDLQGLARHRYIINAFTRMRFCYLDHRLDFACKSPLKYAPTELTPWFNLGNPLYKQIPIVFGHWASLVDEPTPKGVYALDTGCVWNNRMTMLRWEDKQIFTQSAVKNYSDF
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.