PharMolix/UniProtQA huggingface dataset:
Protein: DCDA_ECOLW
Sequence: MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALKQFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTHPDDIVFTADVIDQATLERVSELQIPVNAGSVDMLDQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGENSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVIEFGQDLQAISAGGGLSVPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQSGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVETVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLLPEVLFDNGQARLIRRRQTIEELLALELL
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.  Is not active against the DD- or LL-isomers of diaminopimelate.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: THIO_METJA
Sequence: MSKVKIELFTSPMCPHCPAAKRVVEEVANEMPDAVEVEYINVMENPQKAMEYGIMAVPTIVINGDVEFIGAPTKEALVEAIKKRL
What is the function of this protein?
Acts to maintain redox homeostasis; functions as a protein disulfide reductase.
What are the official names of this protein?
Thioredoxin.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIKC_DESVH
Sequence: MVPPRWGSLDSLKPQQHLPMTKKGILLAAFGSGNRQGESTLRLFDERVRERFPGVPVRWAFTSVIMRRRLAAARKKTDSVLKALQKMWFEKYTHVAVQSLHIIPGAEYGDLVADVEAMRRDDGFTAATVGAPLLAGSGDMERSAAALLAHLPAGRKPDEAVVFMGHGTRHPAESSYEALAALVRRVDPHVHIGTMGGSRTLDHILPELQQGGVKGVWLMPLLSVVGRHATEDMAGTDPESWKSRLEASGLRCIPVLRGTAEYEGFVDIWLDHLTAAVSALDD
What is the function of this protein?
Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis.  To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme.
What are the official names of this protein?
Sirohydrochlorin cobaltochelatase CbiKC, Sirohydrochlorin ferrochelatase CbiKC.
What is the protein family that this protein belongs to?
Belongs to the CbiK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLOC_GLAL2
Sequence: MRIETLDFSKFHVGTDAERYEFSTALLTGFANAGFIKLINHGFSQEEISQLFEENRRFFDLTDSIKAQIANEDGPKPQRGWSAVGAEKTGLLNTGGKTNLTKPDIEAPQDAKEHFDIGPSEDTEFPNKWPDNELIPGFQPWLESFYERSRYISFALMEALEIAMHLPKGAFIQKCQGHASELRLNHYPKITVKTLQGGKTSRIWPHTDFGVITLLAQDDVGGLEIQDKDNPTNFLPVSREDVSELVVNIGDTLERWTNGFLKAGLHQVTTPREIVNQSTETVRPRRSIAFFLKAHRQMSVGPLPQFVAEKTPAKYEDITALAYQQRRTAIVY
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of pneumocandins, lipohexapeptides of the echinocandin family that prevent fungal cell wall formation by non-competitive inhibition of beta-1,3-glucan synthase (PubMed:27705900).  The 10,12-dimethylmyristoyl side chain is synthesized by the reducing polyketide synthase gloL/GLPKS4 (PubMed:27494047).  The thioesterase gloN/GLHYD exclusively interacts with gloL/GLPKS4 to maintain turnover of the polyketide side chain (PubMed:27494047).  The 10R,12S-dimethylmyristic acid is then transferred to the first thiolation domain of the nonribosomal peptide synthetase gloA/GLNRPS4 by the acyl-AMP ligase gloD/GLligase, followed by its acylation to L-ornithine to trigger elongation of the cyclic hexapeptide (PubMed:27494047).  L-ornithine, 4R-hydroxyl-L-proline (generated from L-proline by the dioxygenase gloF/GLOXY2), 3S-hydroxyl-L-homotyrosine (generated by gloG/GLHtyB, gloH/GLHtyA, gloI/GLHtyC, gloJ/GLHtyD and hydroxylated at C-3 by the dioxygenase gloM/GLOXY1), 3R-hydroxyl-L-glutamine (generated from L-glutamine probably by the dioxygenase gloE/GLOXY3) and 3S-hydroxyl-L-proline (generated from L-proline by the dioxygenase gloF/GLOXY2 to yield pneumocandin B0), or 3S-hydroxyl-4S-methyl-L-proline (generated from L-leucine by the dioxygenase gloC/GLOXY4 to yield pneumocandin A0) are sequentially added to the growing chain (PubMed:25270390, PubMed:25879325, PubMed:25527531).  The last C domain of gloA/GLNRPS4 is proposed to be responsible for cyclization by condensation to form the peptide bond between L-ornithine and 3S-hydroxyl-4S-methyl-L-proline (for pneumocandin A0) or 3S-hydroxyl-L-proline (for pneumocandin B0).  Finally, the subsequent C-4 hydroxylation of 3S-hydroxyl-L-homotyrosine and L-ornithine dihydroxylation at C-4 and C-5 are performed by the cytochrome P450 monooxygenases gloP/GLP450-1 and gloO/GLP450-2, respectively (PubMed:25879325).
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase gloC, Leucine dioxygenase, Pneumocandin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RL28_NOCSJ
Sequence: MAAVCDICAKKPGFGNNRPWSRKITKRRFDPNIQRVRATVNGTPKRLNVCTGCLKAGKVTR
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: UBA4_NEOFI
Sequence: MENLEQTCASLRAQIAATEAQLAGLKRELEIAEQAAADVKAQDTTITITADEGRINGTRTWPLLSEEYKRYGRQMIVPQVGLQGQLKLRSARVLIVGAGGLGCPAALYLAGAGVGTLGLVDGDTVENSNLHRQVLHRSKNVGKFKVDSAIEYLREAHLTPQEAPSIFKDYDIILDCTDNPATRYLISDTAVLLGKPLVSASALRTEGQLMVLNYPPRPVGDKSGGPCYRCVFPKPPPANSVVSCADGGILGPVVGTMGVLQALEAIKVITSPAVNPSASPPSLLIFSAYSTPPFRTIRLRARRANCAVCSADASVTLETLKIGSTDYVFFCGVAGLEATLSPEERISPLELRKRHPKEVPQDGGSISKEPTIIDVREKVQFDICNLEHSVNIPISTILSSASNAANADANAQPSLPSWLPRELASADSTNPIYVVCRHGNDSQIAVRRLKELGLDRGGQRYVGDIQGGLRAWREQIDPDWPEY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a.  Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions (By similarity).
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase uba4, Common component for nitrate reductase and xanthine dehydrogenase protein F, Ubiquitin-like protein activator 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH602_ROSCS
Sequence: MAKQIIFNEQARAALKHGVDTMALAVKTTLGPRGRNVAMGKKWGSPAVTHDGVTVAKEVELKDPFENMGAQLLKEAASKTNDVAGDGTTTATVLAQAMIDEGLKLVAAGANPMILKRGLDKGREALVARIKEQAISLKSRDEIRQVATISAQDPEIGELLATIMDKIGHDGVVTIEEGKGTTLEYELVEGMQFDRGYISPYFVTDSSRMEAVIDEPYILITDKKISAVNDLLPVLEAVLATGKKDLVIIAEDVDGEALATLVVNKMRGTLNPLAVKAPGFGDRRKAMLQDIAILTGGTLISEEVGRKLDSAKVQDLGRARRVKSDKDNTVIVEGFGDKQAIQARIRQLKQQIETTTSDYDREKLQERVAKLSGGVAVIKVGAPTEPALKERKARVEDALNATRAAVEEGIVPGGGVALLNAISALDNVQTQFEEERMALNVLRRALEEPLRQLAINAGEDGSVVVNQVRTLQREHNNPHYGFDVMTGNYVDLMQAGIIDPAKVVRSALENAVSVAGIVLTTDALITEAPEPKKNGARTPSMPDEEF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_HELPY
Sequence: MSLFDFFKNKGSAATATDRLKLILAKERTLNLPYMEEMRKEIIAVIQKYTKSSDIHFKTLDSNQSVETIEVEIILPR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity).
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: I2BA_CONEM
Sequence: CFPPGIYCTPYLPCCWGICCGTCRNVCHLRIGKRATFQE
What is the function of this protein?
Inhibits the vertebrate voltage-gated potassium channels Kv1. 1/KCNA1 and Kv1. 3/KCNA3.
What are the official names of this protein?
Kappa-conotoxin-like Em11.10.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: STX6_RAT
Sequence: MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQGPSAATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQIVRDMKDQMSASSVQALAERKNRQALLGDSSSQNWDAGVTDRYGRLDRELQLANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLDDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLTLFLVL
What is the function of this protein?
SNARE promoting movement of transport vesicles to target membranes (PubMed:30962439).  Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking (PubMed:30962439).  Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway (PubMed:30962439).
What are the official names of this protein?
Syntaxin-6.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type IV membrane protein.
Protein: SYM_FLAPJ
Sequence: MIQNPKRYTITAALPYTNGPIHIGHLAGVYMPSDIYSRYLRLQGKDVAFMCGSDEHGVAISMKAKKEGITPQEVIDKYDGIIRKSFVDFGISFDNYSRTSAKIHHDTASEFFKKLYDKGDFIEEVTEQLYDAKADQFLADRFVVGTCPKCGNEEAYGDQCEKCGSTLNATDLINPKSTITGETPIMKSTKHWFLPLDRYSDFLTKWILEGHKSDWKPNVYGQVKSWIDGGLEPRAVTRDLDWGIDVPVAGAEGKKLYVWFDAPIGYISATKEWAAREGKDWELYWKNEDTKLVHFIGKDNIVFHCIIFPAMLKAEGSYILPDNVPANEFLNLEGNKLSTSKNWAVWLHEYLEDFPNQQDVLRYALTANAPESKDNDFTWKDFQARNNNELAAIFGNFINRVVVLTNKYYEGVVPTPNKFSEVDEATLTELKAYPAVISSSIERYRFREALGELMNVARLGNKYLADEEPWKMVKTDPERVKTQMYVALQIATALRVLCEPFLPFTAEKLNKMLKIDAKLSWNDVTTNSDLILAGHKIGEGEILFAQIEDEQIQKQIDKLEATKTANIAENKKAEPQKELIQYDDFAKMDLRVGTIIEAEKMPKANKLLVLKVDTGIDVRTIVSGIAESFSPEEIIGKQVTVLVNLAPRALRGIESQGMILMTNLPDGKLAFVNPDVAGVGNGEGIN
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLE1_STAEQ
Sequence: MQKKYITAIIGTTALSALASTHAQAATTHTVKSGESVWSISHKYGISIAKLKSLNGLTSNLIFPNQVLKVSGSSSRATSTNSGTVYTVKAGDSLSSIAAKYGTTYQKIMQLNGLNNYLIFPGQKLKVSGKATSSSRAKASGSSGRTATYTVKYGDSLSAIASKYGTTYQKIMQLNGLTNFFIYPGQKLKVPGGSSSSSSSNNTRSNGGYYSPTFNHQNLYTWGQCTWHVFNRRAEIGKGISTYWWNANNWDNASAADGYTIDYRPTVGSIAQTDAGYYGHVAFVERVNSDGSILVSEMNWSAAPGNMTYRTIPAYQVRNYKFIH
What is the function of this protein?
Peptidoglycan hydrolase involved in the splitting of the septum during cell division.
What are the official names of this protein?
N-acetylmuramoyl-L-alanine amidase sle1.
What are the subcellular locations of this protein?
Secreted. Cell surface.
Protein: SCP_HHV6U
Sequence: MTTIRSDDLSNQITQISGSSKKEEEKKKQQMLTGVLGLQPNMASHPVLGVFLPKYAKQNGGNVDKTAFRLDLIRMLALHRLNTKTGSD
What is the function of this protein?
Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument.  Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly.
What are the official names of this protein?
Small capsomere-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae small capsomere-interacting protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RIFK_ASPNC
Sequence: MRPDRPRDPVTGPDEGPESPYPIRMSGPVIKGFGRGSKELGIPTANIPADELSQHPELSVGVYYGVVALDPARFSTGETVLPAVLSIGYNPFYKNESKSIEIHIMPPLSAPSPTATTSTDGQVTFHKLPDFYGTPLNLLILGYIRPEYDYISSEALIEDIRVDCEVARRSLQRPAYRCYLDARAVEDPACGGDDCGIVVDAIDGGAMRGMRFCI
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
What are the official names of this protein?
Riboflavin kinase, Flavin mononucleotide kinase 1.
What is the protein family that this protein belongs to?
Belongs to the flavokinase family.
Protein: MACA2_HUMAN
Sequence: MAGCTRKLTHLRKRIHRPRRRTTRRWKRWFKFRKRKGEKRPRPNHKAVARRAKLKFSTSEKLHWPEQELAKKSILNAEDSLIIDNKRSISHLSSGVLKDIFTTGTSSYNVLLQSKEEKKYHSQKQSSSTYSKRCRKPSKSPNTSRSKDPRRMKALVPVTSSGTWYCLERRPAVFVTSSVSSPVKFTHDISVTGNGIVLPPKPKSKVKWCHFSTLPKPKPQLSRSFEKGDDFSGKKFCILTAIKPTNLEKEKLRFFKSDYTYNPQFEYANPALPSVLAKHSHASDRFLKQIVVHLTEDLLSRASMTVVNGCPTLTINVSTAREHWLEGMLRHEIGTHYFRGINNLQQPWNSWTGRKKHELKPNNPTEEGLASIHSVLFRKDPFLWRAALLYYTVYQASQMSFCELFKDIGRFVKDPNTRWDYCVRAKRGWTDTSQPGCFSKDQVYLDGILQILRYRDTIDFHLLTALGKVSYEDVDRLKGLAVTENMRVPHFLQDHGRYMEHLEKIMEVNELTDRELKDLI
What is the function of this protein?
Putative tyrosine carboxypeptidase.
What are the official names of this protein?
Putative tyrosine carboxypeptidase MATCAP2.
Protein: PLCD8_ARATH
Sequence: MLVTRRWESHPANSPDLILQFFGNEFHGYGDDMPETLRRLTELLGYEKEEDGAGMNAAKKIAAELNRRKDDIPAFRRLRCLELDQLNEFLFSTKLNPPIGDQVHHDMHAPLSHYFIHTSLNSYFTGNVFGKYSILPIIEALEQGVRVVELDLWPDGRGSICVRPSWNFEKPLKLQECLDSIKEHAFTKCTYPLIITFKDGLKPELQSKATQMIQQTFNHMVYHHDPHSLEVFPSPQQLRNKILISRRPPKELLYANDDDGKVGVRNGVEIRQHPADPNYQSLVSFHVVEPRGMLQNVLTGKANKIQRPGWYETDIISFTQKRFLRTRPQRKLLIYAPYKPQRAWMHGAQLIALSRKEEKEKLWLMQGMFRANGGCGYVKKPDFLLNAGPSGVFYPTVNPVVVKILKVKIYMGDGWIVDFKKRIGRLSKPDLYVRISIAGVPHDENIMKTTVKNNEWTPTWGEEFTFPLTYPDLALISFEVYDYEVSTADAFCGQTCLPVSELIEGIRAVPLYDERGKACSSTMLLTRFKWS
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
What are the official names of this protein?
Phosphoinositide phospholipase C 8, Phosphoinositide phospholipase PLC8, AtPLC8, PI-PLC8.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL21_PELPD
Sequence: MYAVIKTGGKQYKVAEGEFLKVEKLVGEVGDSVEFGEVLMIGGEKIVVGAPHVAGATVTAKIAVQGKDKKILVFKSKRRKGTRKLRGHRQHKTVLKIEKISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: METK1_TRIMO
Sequence: MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEDIGAGDQGIMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYLNEGGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDKEILKIVKENFDFRPGMISINLDLKKGGNRFIKTAAYGHFGREDADFTWEVVKPLKFDKASA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOT2_ARATH
Sequence: MFKVARASQYLAITGGGIEDIKLSKKSWVFPWQRCTVFDVSPVNYTFKVQAMSAEKLPFVLPAVFTIGPRVDDTEALILYARLISPHDKQSNHVNELVEGVIEGETRVLAASMTMEEIFKGTKEFKKEVFDKVQLELDQFGLVIYNANVKQLVDVPGHEYFSYLGQKTQMEAANQARIDVAEAKMKGEIGAKERTGLTLQNAAKIDAESKIISMQRQGEGTKAEIKVKTEVKVFENQKEADVAKANSELAMKKAAWTKDAKVAEVEATKAVALREAELQTQVEKMNALTRTEKLKAEFLSKASVEYETKVQEANWELYNKQKQAEAVLYEKQKQAEAQKAEADATFYSKQKEAEGLVALASAQGTYLRTLLDAVQNDYSCLRDFLMINNGTYQEIAKTNALAVRDLQPKISVWNHGGEQGIGGASGSGMKDIAGLYKMLPPVLDTVYEQTGMQPPAWIGTLSK
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
What are the official names of this protein?
Flotillin-like protein 2, Nodulin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane, caveola.
Protein: UVRB_CLOPE
Sequence: MGEFKIQSKFKPTGDQPKAIDTLVQSIENGNRGQTLLGVTGSGKTFTMANIIERTQKPTLILAHNKTLAAQLCAEFKEFFPDNIVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALLERRDVIIVASVSCIYGLGNPEEYKKLTISLRPGMIKDRDEVIKKLIEIQYERNDIDFARGTFRVRGDNLDIIPSSSSSKGIRIEFFGDEIDRIREFDVLTGNIIGERQHVSITPASHFAASEETLEKSIRVIEDELEDRLKVLTAEDKILEAQRLKQRTNYDIEMIREMGYCQGIENYSRILDGRMPGTPPQTLLDYFPEDFLMFIDESHVTLPQVRAMYAGDRSRKTSLVEFGFRLPCAFDNRPLKFSEFESKINQVVFVSATPGEYELDHSEIVAEQIIRPTGLLDPVIEIRPIQGQIDDLYGEIQRTVQRGFRVLITTLTKRMAEDLTKYLKDLNVKATYMHSDIDTLERMKIIRELRLGEVDVLIGINLLREGLDIPEVALVAILDADKEGFLRSETSLIQTIGRAARNSESKVIMYADNITKSMDKSIKETERRRVIQMEYNEEHNITPTTVIKGVRDIIEATKVSEEKENYESEVKKAAKKDIPVEKLIEQYEEEMKEAAKNLQFERAAELRDIIKDLKENSK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGE_SALDC
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNQDGAMGIIVNKPLENLQIEGILEKLKITPEPRDSSIRLDKAVMLGGPLAEDRGFILHTPPSRFASSIRISDNTVITTSRDVLETLGTQQQPSDVLVALGYASWDKGQLEQELLDNAWLTAPADLNILFKTPIAERWREAAKLIGIDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: SYT_ECOSM
Sequence: MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_ECO24
Sequence: MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADPTAMVVATVDEHAQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRISLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: DEGP8_ARATH
Sequence: MQVIASFCSKPNENEFVGRRQLLSSVCSKISQGDVVSHPPVSSVKVTQDWKSNLHELAVKSVPSTTRRILLTSLFMNLCFNPSRYLSALALGDPSVATVEDVSPTVFPAGPLFPTEGRIVQLFEKNTYSVVNIFDVTLRPQLKMTGVVEIPEGNGSGVVWDGQGYIVTNYHVIGNALSRNPSPGDVVGRVNILASDGVQKNFEGKLVGADRAKDLAVLKVDAPETLLKPIKVGQSNSLKVGQQCLAIGNPFGFDHTLTVGVISGLNRDIFSQTGVTIGGGIQTDAAINPGNSGGPLLDSKGNLIGINTAIFTQTGTSAGVGFAIPSSTVLKIVPQLIQFSKVLRAGINIELAPDPVANQLNVRNGALVLQVPGKSLAEKAGLHPTSRGFAGNIVLGDIIVAVDDKPVKNKAELMKILDEYSVGDKVTLKIKRGNEDLELKISLEEKSS
What is the function of this protein?
Probable serine protease.
What are the official names of this protein?
Protease Do-like 8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
Protein: MUTS_BURPS
Sequence: MATQIDASSEAAAATAAAQHTPMMQQYLRIKSEHPDTLVFYRMGDFYELFFEDAEKAARLLDLTLTQRGASAGTPIKMAGVPHHAVEQYLAKLVKFGESAAICEQIGDPATSKGPVERKVVRVVTPGTLTDAALLSDKSDVFLLALCVGHNKRGVASNIGLAWLNLASGALRLAELAPDQLGAALERIRPAEILAADGTIESVPAGMGAITRVPAWHFDIASGTQRLCDQLEVASLDGFGAQALTSANGAAGALLIYAAATQGQQLRHVRSLKVENESEYIGLDPSTRRNLELTETLRGTESPTLYSLLDTCCTAMGSRLLRHWLHHPPRASVAAQARHQAIGALLDAPPNAGLDSLRSALRQIADVERITGRLALLSARPRDLSSLRDTFAALPALRERVAEIASNAAALGRLEAALEPPPGCLDLLTRAIAAEPAAMVRDGGVIARGYDAELDELRDISENCGQFLIDLETRERARTGISNLRVEYNKVHGFYIEVTRGQTDKVPDDYRRRQTLKNAERYITPELKTFEDKALSAQERALARERALYDGVLQALLPHIEGCQRVASGLAELDLLAAFAERARTLDWVAPEFTDEIGIEIDQGRHPVVEAQVEQFIANDCALNPERKLLLITGPNMGGKSTFMRQTALIALMAYVGSYVPAKAARFGPIDRIFTRIGAADDLAGGRSTFMVEMTEAAAILNDATPHSLVLMDEIGRGTSTFDGLALAWAIARHLLSHNRCYTLFATHYFELTQLPAEFPQAANVHLSAVEHGHGIVFLHAVEEGPANQSYGLQVAQLAGVPAPVIRAARKHLAHLEQQSAAQATPQLDLFAAPPVVDEPECNEPPAATPHPALERLLELDPDDLKPRDALDLLYELHTLARSGPADAQR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: YQI8_CAEEL
Sequence: MRLLVCFGFFSFTYFFSRKGTRSYFRWVSTETSNNTRSKCHKLKSESIMTTSLLSRMQIDRDLRRSTEHVEIVPQETCVHHESPDSVLTECATMSTSTHVMPNSSSTISKSATEKKTKTGSKKVTRSKKSKKTKRRSSTTVTTTTISNSKPVTPDKDKDSKDQRKQRTKRKDPFEKEWFGKECDDVTRCKVPIQEFKIAEVQLRPRIEEDQNIEVTSRDIDEADMERICKKFAKEKINPITMAEPIDEKTKILLDRVTKKPYPLKYNNEKGLLLFDERSSFYKSREKKKAEKSESNLEEDTYGQVPKLKDVQRLPPQNVFSRPGVPFWAVTLLPTEEDLVDVDPSISVGTEHLEMYHLKQVPLQTIKKSKLILNALQPLSILEDRDDIHFTPELVFSNTIRSLVHAQEMEGKRNESKSDDEGKSDKSLSFVIEKQEEFIYSRANPIETARMARRNRRSKGSSSKK
What are the official names of this protein?
Uncharacterized protein C45G9.8.