PharMolix/UniProtQA huggingface dataset:
Protein: UX23A_THELO
Sequence: MKYILLGLLLMVVLANANRLADPNCGVCTLRSICFMEKESCPKGFKMLCF
What are the official names of this protein?
U-scutigerotoxin(02)-Tl3a, U-SCUTX(02)-Tl3a.
What is the protein family that this protein belongs to?
Belongs to the scutigerotoxin-02 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARB2_SCHPO
Sequence: MFRKKKSRVLQRDVNFGNCLEDMNLQITNDFYLRKLNAPNELYEFQVTKDKEYNEKFYFAVLDHVYSWTLQNSLLTRISIPLESSPSEPHSWIYATRNWQTNENGIVIIIQSMSHPLIWSNRNLREGDVRRATVLDVIAKCTEKKLSVVIFSPSALLWDQSINFPRTTRYFTSQGLQITKKSIIKDVETPESYVSIGLNYVMSNSVSTKIHFVGSEYGSYLLNSYLDLNWKKFSGKAGAILLIMNMSINEELHDPDYVSYLIEHARNYLPSHEPCRHLMNSIMTESGIPNFSAGKYIDEFYDYIGDVLLEMIALDTNTSKS
What is the function of this protein?
A member of the argonaute siRNA chaperone (ARC) complex which is required for histone H3K9 methylation, heterochromatin assembly and siRNA generation.  The ARC complex contains mostly double-stranded siRNA.  Inhibits the release of the siRNA passenger strand from ago1 together with arb1.
What are the official names of this protein?
Argonaute-binding protein 2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to a large number of foci in both the nucleus and cytoplasm.
Protein: AGT2_BOVIN
Sequence: MTGAWGHLLRSLHLKTLSLWIPKTCFSLKARAFWTSVTRCGLHTKPSMPPCDFTPERYQSLAYSRVLEIHKQHLSPVHTAYFPEPLLLHQGHVEWLFDHEGNRYLDFFSGIVTVSVGHCHPKVNAAAQRQLGRLWHTSSVFFHPLIHEYAEKLSALLPEPLKVVFLVNSGSEANDLAMLMARAHSNSTDIISFRGAYHGCSPYTLGLTNVGIYKMDLPHGMGCQPTMCPDIFHGPWGGSHCRDSPVQTIRKCSCAPDCCQAKDQYIEQFKDTLSTSVAKSIAGFFAEPIQGVNGVVQYPKGFLKEAFELVRERGGVCIADEVQTGFGRLGSHFWGFQTHDVLPDIVTMAKGIGNGFPMAAVVTTPDIAKSLTKRMLHFNTFGGNPMACAVGSAVLEVIKEENLQENSQEVGTYMLLKLAKLRDEFEIVGDVRGKGLMIGIEMVKDKESRQPLPREEVNQIHHDCKCMGLLIGRGGLFSQTFRIAPSMCITKPEVDFAVEVFRSALIQHMERRAK
What is the function of this protein?
Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV).  ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity).
What are the official names of this protein?
Alanine--glyoxylate aminotransferase 2, mitochondrial, AGT 2, (R)-3-amino-2-methylpropionate--pyruvate transaminase, Beta-ALAAT II, Beta-alanine-pyruvate aminotransferase, D-AIBAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: T7418_ILLWI
Sequence: LKFVVLICLVIMASTSAQQCGDETCGAGTCCAVFSQNHCRRLSRMYDLCSDHADASPSGNYLFFCPCEPGLHCDRNTWTCTEGSSRSE
What are the official names of this protein?
U1-hexatoxin-Iw1d, U1-HXTX-Iw1d, Atracotoxin-Hs20f7418, AcTx-Hs20f7418.
What is the protein family that this protein belongs to?
Belongs to the MIT-like AcTx family.
What are the subcellular locations of this protein?
Secreted.
Protein: ESAR_PANSE
Sequence: MFSFFLENQTITDTLQTYIQRKLSPLGSPDYAYTVVSKKNPSNVLIISSYPDEWIRLYRANNFQLTDPVILTAFKRTSPFAWDENITLMSDLRFTKIFSLSKQYNIVNGFTYVLHDHMNNLALLSVIIKGNDQTALEQRLAAEQGTMQMLLIDFNEQMYRLAGTEGERAPALNQSADKTIFSSRENEVLYWASMGKTYAEIAAITGISVSTVKFHIKNVVVKLGVSNARQAIRLGVELDLIRPAASAAR
What is the function of this protein?
Functions as a potential OhlL-responsive transcriptional regulator.
What are the official names of this protein?
Transcriptional activator protein EsaR.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-regulated transcriptional regulatory protein family.
Protein: RL21_RICAE
Sequence: MFAVIKAGGKQYKVDRNSIIKVEKIDGELGSKIQFDQILMIGEYSKPSFIGTPIVKGAVVTAEITNQLKDNKIIVFKKKRRKNYRRKAGHRQELTELKILDITKQ
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RECR_TREDE
Sequence: MNAIDAVIDSFSRLPGIGHKSAARIAYHLLKQGPADALRLAEAVSTLHEKIHPCTICGSYTEDEICSICADETRDRATICVVGFPQDVNTISSIPEYRGLFHVLGGLIAPLEGIGPDQLHISELIRRIHEGGITEVILATNPTIEGDTTALYIQKILQDLPVNITRLASGLPVGGDLEYADRLTLARSLNGRIKF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: FOLD_ECOSE
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: NADA_METJA
Sequence: MSMDIVERINKLKEEKNAVILAHNYQPKEIQKIADFLGDSLELCIKAKETDADIIVFCGVDFMGESAKILNPEKKVLMPEIEGTQCPMAHQLPPEIIKKYRELYPEAPLVVYVNTTAETKALADITCTSANADRVVNSLDADTVLFGPDNNLAYYVQKRTDKKVIAIPEGGGCYVHKKFTIDDLKRVKSKYPNAKVLIHPECSPELQDNADYIASTSGILRIVLESDDEEFIIGTEVGMINRLEIELEKLGKKKTLIPLRKDAICHEMKRITLEKIEKCLLEERYEIKLEKEIIEKAQKAIERMLRI
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SIM7_DENAN
Sequence: MKTLLLTLVVVTIVCLDLGYTLTCVKSNSIWFPTSEDCPDGQNLCFKRWQYISPRMYDFTRGCAATCPKAEYRDVINCCGTDKCNK
What is the function of this protein?
Binds specifically and irreversibly to an allosteric site of the muscarinic acetylcholine M1 receptor (CHRM1) at subnanomolar concentrations and shows a very slow dissociation rate (PubMed:11562434, PubMed:10799315, PubMed:12488533, PubMed:21557730).  It also inhibits agonist-mediated guanosine 5'-O-(3'-thiotriphosphate) (GTP-g-S) binding and downstream signaling, and decreases the dissociation rate of orthosteric antagonists (N-methylscopolamine (NMS) or pirenzepine) (PubMed:10799315, PubMed:15033377).  Is a potent negative allosteric modulator (NAM) for CHRM1 activation and a positive allosteric modulator (PAM) for antagonist binding (Probable).
What are the official names of this protein?
Muscarinic toxin 7, MT-7, MT7, Muscarinic toxin 1, m1-toxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Aminergic toxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UVRB_ECODH
Sequence: MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TT39B_XENTR
Sequence: MAFVSNGTERDADEEGFEDAYENIPVASKMDLRCALEECTLALNLFLNNKFSEALEILRPWAKESIYHALGYSTILVMQSAMTFEPQDVQMGISTMKEALQTCQRFRKRTTVVESLSNLVSKQSGDQLTEEEMHAEICYAECLLQKATLTFVQDENMINFIKGGMKIRTSYQIYKECHQLYSLAVTQGKTCSDTHHQFEGGVKLGIGAFNLMLSLLPSRVLRLLEFIGFSGNREFGLSQLREGASGNSIRAILCVLTLLFYHTYISTILGTGEANLEEAEALLEPYLKKFPNGSIILFYAARIDILKGRFEQAQETFQKCIVSQQEWKQIHHLCYWELMWCHSFQQDWLQAYRYADLLCKESKWSKATYVFQKAAILSMLPDDVVKTTGEDIVALFRQVEGLKQRIAGKSIPTEKFAVRKSRRYASDNPVKLTLPALEMVYVWNGFTIVGKRPDLTENVLVTIEKAEVALQSEKNPSEYHPDDLCLVQLLKGVCLKHLGRLLQAELCFNQVIQSEKRVKYDHYLLPFTFYELGLLYKDQGDRDKAIRYIETAKSNYKDYSLESRLHFRIHAALSSLKGSPVSTPSTPQ
What is the function of this protein?
May be involved in lipid metabolism.
What are the official names of this protein?
Tetratricopeptide repeat protein 39B, TPR repeat protein 39B.
What is the protein family that this protein belongs to?
Belongs to the TTC39 family.
Protein: DYN3_MOUSE
Sequence: MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRHEIEAETDRVTGMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIRDMIMQFITRENCLILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIEHEVEAFKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSLKSVDLVMQELINTVKKCTKRLANFPRLCEETERIVANHIREREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKSTIGNQVIRKGWLTVSNIGIMKGGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKGFMSSKHVFALFNTEQRNVYKDYRFLELACDSQEDVDSWKASLLRAGVYPDKSVGSNKTENDENGQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALAIIGDINTATVSTPAPPPVDDSWLQHSRRSPPPSPTTQRRLTISAPLPRPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPNSSDSFGAPPQVPSRPTRAPPSVPSRRPPPSPTRPTIIRPLESSLLD
What is the function of this protein?
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.  Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity).
What are the official names of this protein?
Dynamin-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.
Protein: Y1142_POLSJ
Sequence: MATDSALINLTHHFLIAMPGLEDEAFAKSVVYMCEHSDRGALGLVINKPSDINLKNLFDKVELPLRRDDLTEAPVFQGGPVQTERGFVLHESMMPGSESVYASTMTIPGGLEMTTSKDVLEALSTGAGPRKVFVSLGYSAWGEGQLESEISDNSWLTVPADVAVIFDTPVEQRYDKALMLLGLQSWMLSPDAGHA
What are the official names of this protein?
UPF0301 protein Bpro_1142.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: MSRP_ERWT9
Sequence: MKAVNPLTENDVTPESLFNARRRTVLKMLGMSAAALSLPGAARADLLSWFKGGDRPRAASGRPLDFSQPQQFQANLPLTPEDKVTGYNNFYEFGLDKADPAAHAGTLKTADWKIEIDGEVAKPLTLSMDDIFKRFAQEQRIYRMRCVEGWSMVVPWVGFELGKLLQAAEPTSNARFVAFHTLYAPDQMPGQQDRFIGGGLDYPYVEGLRLDEAMHPLTLLTTGVYGKALPPQNGAPIRLTVPWKYGFKGIKSIVKISLVKAMPPTTWNQLAPNEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: MACB1_YERPE
Sequence: MAALLELEGIRRSYQSGEEIVDVLQDVSLTINAGELVAIIGASGSGKSTLMNILGCLDKPSAGIYRVAGQNVDELDDDALAALRREHFGFIFQRYHLLPHLSAAHNVEVPAVYAGLGKHERRERANMLLTRLGLGDRVSYQPNQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSSVEVMAILKQLQQQGHTVIIVTHDPTVAAQAERVIEIKDGRIMADSGSKNEPVVAAAELMSLTPAAPSWQQLVGRFREALLMAWRAMSANKMRTALTMLGIIIGIASVVSILVVGDAAKQLVLADIRAIGTNTIDIYPGKDFGDDDPSTRQALVHDDMAALKAQSYVSAVSPSIGGSMRLRFGNIDVAASVLGVSDEYFRVFGMAMEQGAPITREQVERQAQTVVIDLNTQRRLFPHMKDVVGQVILVGNMPATVVGVVAEKKSMFGSNKALRVWVPYSTMANRLMGRSYFDSITIRIKEGYSSKEAEQQLVRLLTLRHGKKDIFTYNMDSLLQTAEKTTQTMQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARSSDVMQQFLIEAVLVCLIGGALGISLSFAIGLIVEMFLPNWRIAFPPMALFSAFLCSTVIGVVFGYLPARSAARLNPIDALARE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL14_PROM1
Sequence: MIQQETFLTVADNSGAKRLQCIRVLGSNRRYAHVGDVIVASVKDAMPNMGVKKSDVVKAVVVRTRATMRRETGNSIRFDDNAAVLINDDQNPRGTRVFGPVARELRERNFTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NCOR1_CAEEL
Sequence: MESFKELAREYDEKFKAFQDDLQKWEETSERKEYAEFHRVQAESEFPELKREREDRERWARAERIRGEDEKSMLAKEHADKKIRLGVAKIPRLLTESERKMDEFVERPGSILKDMKKEHRQSVLDRLEEWSPEERSLFKSRQADHVKIFHGLTEFFVDKTASDLVLFYYMNKKTEDYKKDFKPKKRVTKYKVGAFPSVEELAYFRMMPPLDFSSFPKNSLMCYFCCRTVNGIDLNGTFMPKEAYEIFAICPDEDRVVCSGCREEAAKLYKDNRCFGNRCSNQKKRANRVNRNIPLDFADFPVRTRAFIMDKLGSTRVAVKFCTPCKNALTRWINDVNNKEETIMAELLNYEGQVGWTDDEKTKLVTLINSSPTLDWVSISEGMNRRPNECKMQYDAMNGVKTQPMIEEVDEEDGNGQEEGGDALVNTPTTSSAAARRSGLARNAKKPVRTPRAPRSAGGRRTGGAVTRAQAVPKPVEDLGEEIDEMEIEDNDEDASRGSRGKDSKAPSDRDGSPADMEGDSPEGQDQDADQDQDQDQDVDEEEEEVIVRDIDSPVKTLLSPKILSGGHKPDFPPVPRIQKPSTSSQPPPPEPMDTKENESDDGEEDNDILEIDVDEPPAKRPTPTSSSSHLIGSSSVGGSERELGGRGLVQQQQQQQPQAQSAAPPVTVSTAAAATAERLVNATSPSPSVASQHLVPTETSTSVPPVTIVPPAIQQPVVVISGAAPQFTQQQTTHSPALIAQPIPQQLIPQRVSTPAQILTPTPVRPTAASTPSMDQFLGLFKQQQQQQQQQPQQSNLMQQLGNINPQFLALLLQQQQQQQQVQQAQVQAAQTQGSLTSGTPFQAQQRPDEALQKLFSSPEMLGTLLNAKYQFPQFPQAIQQNPLLMNAQHQLILQQQQLAMQHAQAQAAQAAQAQAAQAAQAQAQAQAEAKLKTQAAQAKAQADAQARVQTQQQAHLKAQAQAQYQMNRPQLIPASVQMPIGINTAYHQKSLTPSETSASATPPAHRPRAATTVGSKMPAGRSNVQEAELRTLKEELIKRIRLFRDRIAEDAHLKREEENIVTYTAQIQASRVQYNTEILGQMKQRYEQAAARRIEIVKELDEPAKFINGVQNKFNDFSVFKLDEIDRQTLHEILQRYAAEQKPDQLQQQQNDFHNLLRQNNIGIRQAQYPALQASPHQAAIIQHQQQQEAFKKLQQQHQDAQKRKLEAPVSSATPQVKRIALSQSSPVQRFSQHPNGTLPHNLAVVYQNKMPQDREKLLQEQQLNQYLFAAQQQHLQQQQQHHGTQPEQKSKRKSGIESITSMQGAPHRHIQLAGPSSSRIQSGRGVSPALSASRSVAPTISGAAGRSITAGTSGHSSTSDYNKELAERMNEVFKPTHPQLLQTKASAMNSNAVSPANTNNSDEIECVYQGPPKTPASIKRLQPTEGPRTLSGQRMKSILSVPAHQRRSSIPPVKTEDEAMECLSMMMYEEAKAPPSDRIVTKLISSSEAAAAANPSAKFSYLDIFNDVVKRDEERCQRMLQSTSVLQPSRELDAFLQQLQQNPQQYANLSAAEKLALQQYQIHSAHQKSQQQAQLQAAQQLQQQQQARPDHYEKFHLLRPNAEIVRPIPTTFSHFLNKATTSTVSSSASAPQFLQPPAAASIAAPTPISTPHAMPSPSVGVQTAPPTPQAVHHPVMPIIPGKPSSVNSNVSDVSSDDDDVRNPEKLPANRLPPLPGDKTAFRSVIDLRATGHVAVTKKIPVKYPLVVQAQNGIQPIKDYGPPCKNLVYEDLSDDE
What is the function of this protein?
Mediates transcriptional repression by certain nuclear receptors.  Plays a role in development and neuronal function.  May play a role in muscle-specific oxidative mitochondrial metabolism.
What are the official names of this protein?
Nuclear receptor corepressor 1, N-CoR, N-CoR1, Gex-3-interacting protein 8, Prion-like-(Q/N-rich) domain-bearing protein 12.
What is the protein family that this protein belongs to?
Belongs to the N-CoR nuclear receptor corepressors family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TX1AA_ECTBR
Sequence: INFGAIKAILKKWGKKLVEYALKHKDLYAPYIKKHLCEKL
What are the official names of this protein?
U1-ectatotoxin-Eb1a subunit A, U1-ECTX-Eb1a subunit A, Ectatomin-Eq1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the ectatomin family. Ectatomin-Eq subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: KIF1C_MOUSE
Sequence: MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSVEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLCEDLFSRVNVNQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRSHDQLTGLDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADLQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAVINEDPNARLIRELQEEVARLRDLLMAQGLSASALGGLKVEEGSPGGVLPPASSPPAPASPSSPPPHNGELEPSFSPSAEPQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREALLAEMGVAVREDGGTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVGQVDVDIKLTGQFIREQHCLFRSIPQPDGEVMVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHPEQARLERERGVPPPPGPPSEPVDWNFAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGEDSDKRSCEESWRLISSLREQLPPTTVQNIVKRCGLPSSGKRRAPRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMRELCRTYGKPEGPGDAWRAVARDVWDTVGEEEGCGGGGGGSEEGARGAEVEDLRAHIDKLTGILQEVKLQNSSKDRELQALRDRMLRMERVIPLTQDLEDDNDESGLVTWAPPEGPEAVEETVPNDHSPAVRPTSPPLSSWERVSRLMEEDPAFRRGRLRWLKQEQLRLQGLQGAGGRGGGLRRPPARFVPPHDCKLRFPFKSNPQHRESWPGMGSGEAPAPQPPEEVTVPPAPPNRRPPSPRRPHRSRRNSLDGGSRSRGGGSTQPEPQHLRPQKHNGYPQQPQPSPAQRPGPRYPPYTTPPRMRRQRSAPDLKESGAAV
What is the function of this protein?
Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum.  Has a microtubule plus end-directed motility (By similarity).
What are the official names of this protein?
Kinesin-like protein KIF1C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RLMH_BACCR
Sequence: MNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEMLIVKEKEGIRILDKISDDTHVIALAIEGKQKSSEEFAISLDRLATYGKSKVAFVIGGSLGLSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRINRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTI2_HUMAN
Sequence: MELDSALEAPSQEDSNLSEELSHSAFGQAFSKILHCLARPEARRGNVKDAVLKDLGDLIEATEFDRLFEGTGARLRGMPETLGQVAKALEKYAAPSKEEEGGGDGHSEAAEKAAQVGLLFLKLLGKVETAKNSLVGPAWQTGLHHLAGPVYIFAITHSLEQPWTTPRSREVAREVLTSLLQVTECGSVAGFLHGENEDEKGRLSVILGLLKPDLYKESWKNNPAIKHVFSWTLQQVTRPWLSQHLERVLPASLVISDDYQTENKILGVHCLHHIVLNVPAADLLQYNRAQVLYHAISNHLYTPEHHLIQAVLLCLLDLFPILEKTLHWKGDGARPTTHCDEVLRLILTHMEPEHRLLLRRTYARNLPAFVNRLGILTVRHLKRLERVIIGYLEVYDGPEEEARLKILETLKLLMQHTWPRVSCRLVVLLKALLKLICDVARDPNLTPESVKSALLQEATDCLILLDRCSQGRVKGLLAKIPQSCEDRKVVNYIRKVQQVSEGAPYNGT
What is the function of this protein?
Regulator of the DNA damage response (DDR).  Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins.  The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC).  Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
What are the official names of this protein?
TELO2-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the TTI2 family.
Protein: DRB8_ORYSJ
Sequence: MDMPPTPLPPETANTSPAPNGATAGIRVENCYVFKSRLQEYAQKTGLQTPEYHTFKEGPSHEPVFKSTVVINNTSYDSLPGFFNRKAAEQSAAEVALMEIVKSIPANANIPAVQETGLCKNLLQEYAQKMNYAIPSYICTKSASGLAPFICTVEIGGIQYIGAAARTKKDAEIKAARTALLAIQGQSEGSANGATKYIVVPGKRVGKEVEKRPIETPKPLKVKKGGFKKKWNKRKFMKKDGQAVDVEKDEARVAGDAHDSDVLMQPTVITQEASCGTLFLQPCEEAKRVEAEPPRDIEMVQPDKENQHSDAALVQPDDEARVEQEPSRDISVVQPNEEAISGKQEPSIDAAILQPKEEASSVKQEPFIDTAMLQACKEAGSVELGPARDTVISQLNEQDRAVKQEPAGDIVVPQPDVHARVVKE
What is the function of this protein?
Binds double-stranded RNA.
What are the official names of this protein?
Double-stranded RNA-binding protein 8, dsRNA-binding protein 1, OsDRB1, dsRNA-binding protein 8.
Protein: RSD_SALTI
Sequence: MLNQLENLMERVGGSNKLVDRWLDVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLLHAAKIWPLLEDNTQRIMDYYDTSLETAIDHDNCLEFQQALSDIGEALEARFVLEDKLIMLVFDAMHDGARVKRPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_GRALE
Sequence: KNMITGAAQMDGAILVVSAADGPMPQTREHILLAKQVGVPNIVVFLNKQDQVDDEELLELVELEVRELLGQYGFPGDNIPFVAGSALRALENITQNNTIQRGENEWVDKIHSLMDAVDEYIPTPVRDVEKTFLMAVEDVFSITGRGTVTTGRIERGIIKVGDTIEIVGLRETTTTTITGLEMFQKTLDEGMAGDNIGILLRGVQKKDIERGMVLAQPGTITPHTQFEAEVYVLTK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, chloroplastic, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPL_CROS8
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.