PharMolix/UniProtQA huggingface dataset:
Protein: HTPX_BRUAB
Sequence: MNMTKTAMLIALMTVMFMSIGYLLGGGGGMMIALVIAVAMNLFGYWNSDKMVLRMYNAQEVDERSAPEYYRMVSGLAANAGLPMPKVYIIHEDQPNAFATGRNPENAAVAATTGLLNRLSPEEVAGVMAHELAHVQNRDTLTMTIVATLAGAISMLGNFAFFLGGNRENGNGVMGVVGTLLAMIVAPFGAMIVQMAVSRTREYAADKRGAEICGNPLWLSSALGRIARGAKVIPNEEAEHNPATAHMFIINPLSGRGADNLFSTHPDTDNRIAALEQMAAEMGIRSAAMTARAAAPSQNSGPWGQRSDNAGGNSNGGSRYRGPWS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PNP_PERMH
Sequence: MEGIGDITVEKVETKIQETPISIETGYFAKQSNGAVIVRQGETAVFVAAVISEEAQADIDFLPLTVDYREKTYAYGKIPGGFVKREGKPTVREILVSRLIDRPIRPMFPKGFFNDVIITAMTLSADDKYDPDVLAIVGASAALHITEAPFEGPVAGVRVCRLDGEFIVNPTYEQRNRSDIDIVVAGTKDAIVMVEGGSEEVSEEVILDAILFAHEEIKKLCDLQEELRSKVGKEKITVEIDEEDERIKAELESIVRESVKEAFNILDKKERNKRIKEIYEEAIQKIEIPEEKEKKAEVIYKEIVSNIMREKVLKEKVRIDGRRPDEIRPIWIRTGLFPRIHGSAIFTRGQTQAFVATTLGAPGEEQIEESIEEGEEKKRFMLHYNFPPFSTGEARPPRAPSRREIGHGNLAERAIEPLIPDEEEFPYVIRVVSEILESNGSTSMATVCGASLSLFDAGVPMKKHVAGIAMGLLKEDDDYVILTDILGDEDHLGDMDFKVAGTRDGVTSIQMDIKIKGLSKEILQEALEQAKKARMHILDLMYKAMPQPRPELSPHAPKVITMRVLPEKIPVIIGPSGKNIKKIIDETGVKIDLDQEGLVRIYAVDGESADKAKEMIERLIMDIELGEVYMGKVTRVEDYGAFVELMPGKLSLLHVSQISPERIRSAKEKIKVGDILTVKVIDIDEMGRAKVSLKEVREGEEPKNKFLFE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_ECOL6
Sequence: MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: C96T2_NARAP
Sequence: MATSSSAWLMFSDHYPEILIAIACFLIFSLLLSARSSSEDSLPYNWPIFGMLPAIISNNQFNDFTTARLRKMGWTFIFKGPWLLDMDYIFTCDPSNINHMFNDNFENYPKGELGKVFDIFGNNIFNADGDLWHDHRKMAQTILWDGNYRTMQATFIRNKMDNALIPILDSAACKRKPVDLQDVLLRFTFDTSCFSVLAADPESLTMEFPPVPFSKAADQALDAALTRHITPRLIWKLKRFFNVGSERTLAVAWKVIDSYIYDKIAELKAKRKLVGKINSYDAVSFYMDNFNIHDDKFLRDNAFTYLLAQRNTQSLTMTWLFYALFENPKVELKILSELKSIVDESSERKFNDGFTLFDSNMIQSAIYLHAALCEALRIYPPVPFEIKDAHKADVLPSGHKVRAGEKILFSPYAMARMKGIWGDDCLEFKPERWITGNGTLKHEPAYKFFAFSAGPRICLGKELSFTQMKMVVATIIYNFHLQMVKGHVVEQSNSILMDMKHGLMVQVRKRSVM
What is the function of this protein?
Cytochrome P450 that catalyzes an intramolecular para-para' C-C phenol coupling of 4'-O-methylnorbelladine in alkaloids biosynthesis, including haemanthamine- and crinamine-type alkaloids, promising anticancer agents.  Catalyzes the formation of (10bR,4aS)-noroxomaritidine and (10bS,4aR)-noroxomaritidine from 4'-O-methylnorbelladine.
What are the official names of this protein?
Noroxomaritidine synthase 2, CYP96T2, Cytochrome P450 96T2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: URM1_SCLS1
Sequence: MTTETLNIMVEFTGGLEMLFSDQRNHKLTIPQTDSKGDPVTVGWLVNYLCEEIMQDSRKDMFILDDHVRPGILVLINDADWELEGEASYVLQPNDNILFVSTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBTB7_HUMAN
Sequence: MQSREDVPRSRRLASPRGGRRPKRISKPSVSAFFTGPEELKDTAHSAALLAQLKSFYDARLLCDVTIEVVTPGSGPGTGRLFSCNRNVLAAACPYFKSMFTGGMYESQQASVTMHDVDAESFEVLVDYCYTGRVSLSEANVQRLYAASDMLQLEYVREACASFLARRLDLTNCTAILKFADAFDHHKLRSQAQSYIAHNFKQLSRMGSIREETLADLTLAQLLAVLRLDSLDIESERTVCHVAVQWLEAAAKERGPSAAEVFKCVRWMHFTEEDQDYLEGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSSSSSSSNSLVSAAENPPQRLGMCAKEMVIFFGHPRDPFLCYDPYSGDIYTMPSPLTSFAHTKTVTSSAVCVSPDHDIYLAAQPRKDLWVYKPAQNSWQQLADRLLCREGMDVAYLNGYIYILGGRDPITGVKLKEVECYSVQRNQWALVAPVPHSFYSFELIVVQNYLYAVNSKRMLCYDPSHNMWLNCASLKRSDFQEACVFNDEIYCICDIPVMKVYNPARGEWRRISNIPLDSETHNYQIVNHDQKLLLITSTTPQWKKNRVTVYEYDTREDQWINIGTMLGLLQFDSGFICLCARVYPSCLEPGQSFITEEDDARSESSTEWDLDGFSELDSESGSSSSFSDDEVWVQVAPQRNAQDQQGSL
What is the function of this protein?
As part of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex functions as a substrate adapter for the RAC1 guanine exchange factor (GEF) TIAM1, mediating its 'Lys-48' ubiquitination and proteasomal degradation (PubMed:25684205).  By controlling this ubiquitination, regulates RAC1 signal transduction and downstream biological processes including the organization of the cytoskeleton, cell migration and cell proliferation (PubMed:25684205).  Ubiquitination of TIAM1 requires the membrane-associated protein GABARAP which may restrict locally the activity of the complex (PubMed:25684205).
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein 7.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NKD1_MOUSE
Sequence: MGKLHSKPAAVCKRRESPEGDSFAVSAAWARKGIEEWIGRQRCPGSVSGPRQLRLAGTVGRGTRELVGDTSREALGEEDEDDFPLEVALPPEKIDSLGSGDEKRMERLSEPGQASKKQLKFEELQCDVSVEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKTLRVKLTVAPDGSQSKRSVLFNHTDLQSTRPRADTKPAEELRGWEKKQRAPLRFQGDSHLEQPDCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRISNPTRSRSHEPEAAHIPHRRPQGVDPGSFHLLDTPFAKASELQQRLRGTQDGSKHFVRSPKAQGKNMGMGHGARGARSKPPLVPTTHTVSPSAHLATSPALLPTLAPLGHKKHKHRAKESQASCRGLQGPLAAGGSTVMGREQVRELPAVVVYESQAGQAVQRHEHHHHHEHHHHYHHFYQP
What is the function of this protein?
Cell autonomous antagonist of the canonical Wnt signaling pathway.  May activate a second Wnt signaling pathway that controls planar cell polarity.  Required for spermatogenesis.
What are the official names of this protein?
Protein naked cuticle homolog 1, Naked-1, mNkd, mNkd1.
What is the protein family that this protein belongs to?
Belongs to the NKD family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm.
Protein: Y522_AQUAE
Sequence: MRGILGLVFGSVILIYLISLFLMKHPFFQIREIKVSGLYVEEIEKIEKDIHALGRGLLVIPESNILELFNEKLNNRFQGVEINKRFSTEGITIEMNFQRRKAISFVNINEKKFLMDMEGIFFWDEYQKPDKTLFIYSKEVFQFFKQKILKLLTQGNSVKVYKDKVMVDIGGKRFILPPLEDINEKEIHLMKKLLKLHPDAKIFDIRYKGFILLNEG
What are the official names of this protein?
Uncharacterized protein aq_522.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y2764_BACLD
Sequence: MQTPVSVNEKKDFIRWFLNHYQLKRRECVWILNYLMSHDSLMEKVHFVEQAEFCPRGIIMSTHCVEEVPFRFYKENVMTTDAEKSFHDIRLNKQQDLFIQLNFRSAYNSPEYAAVLEANPHIPKDLYENEKDKIVAEQILEHSIATFQRQKLLREIDEALDRQDKESFEKLAKQLSQLR
What are the official names of this protein?
UPF0302 protein BLi02393/BL02764.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: Y1005_PYRIL
Sequence: MFRPYTIEEGAYLVKLARSTVETFLKTGKIIIPESPPQRLLIDNYGVFTTIETVSGDRYELRGCIGYPEGYKNTLYATIYSAIGACCQDPRFPALRIDELPHVIFEVSILSPLTLLQDDPRKYPELIQVGRHGLVVRRGPYAGLLLPQVAVEECWDAEEFLLHVCMKAWLPGDCWLDRRTKLYIYEAQIFREKTPGGEIYERNLVAETAKCSPKTRRENEQ
What are the official names of this protein?
Protein Pisl_1005.
Protein: RSMH_DESRM
Sequence: MEFKHVSVLLHESIDGLKIKPGGIYVDCTLGGAGHSLEILRRLGPEGKLVGIDQDPAAIANAAEKLQEFPGQFHAVQRNFFQIKQILREMAISEVDGILFDLGVSSYQLDTPERGFSYMHDAELDMRMGPDQTISAKELVNDISEEELATIIRRYGEDRWAKRIASFIVKERKKRAIHTTGELVDIIKAAVPVGARREGPHPAKRTFQALRIAVNNELEILEQTMKDAVTALKSGGRISVITFHSLEDRIIKDTFKELANPCTCPPAFPVCACGKQPQIKIVTGKPIQPSKEELEHNPRARSAKLRIAEKLNI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_BLOFL
Sequence: MNISFEKFLECLSIFMHSFFVLLMVVMCGAYMSFVERRLLALFQNRYGPNRVGWNGSLQLLADLIKIMFKEDWIPPFSDRYIFVLAPAIAFIISLMIIPVIPFTPSSVILHCNVGVLFFLMISALTVYSVLLAGWSSNNKYALIGAVRSIAQTLSYEVFLGLSLMGIVAKSGSFDLLNIVQDQKYLWNIVPQFLGFVVFFISGMALCHRHPFDQPESEQELVAGYHIEYSGMKFSLFFISEYISVISISSFMVTLFFGGWYGPWFPPVVWFIIKTFMIVLFFVLIRASLPRPRYDYVMLVGWKFLLPIALLNLLVTAGYILI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRSA2_LACPL
Sequence: MKYRLIGVGASLVVAVMLTGCQAKATTLVKSDAGQVTQAEVFKQIENQATTQQAVQELTLNKVLNQRYHVSQAEVTAKLKAFKRQAGANYHMILERNHVTEPRLKSQIKANLLMEKAVSAKYPVTKAQLKKARAAYMPMTTVQHIATTNEKQAQKIIAELNAGASFDSQVRKYQNNRQAHTTAGKLAQFDSYNQTLAPAIVQATAKLRVGHYVTKPVKTVMATADTKDKPTYEIINVVSRRSKTAAVTDDSGKQIDVTNYLREKIQQQRMMDKQTQVATIRSVFKAAHVKVVDAHFAPAFNDYLTTQNS
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 2.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: KPYK_STAES
Sequence: MRKTKIVCTIGPASESEEMLEKLMNAGMNVARLNFSHGSHEEHKARIDTIRKVAKRLNKTIGLLLDTKGPEIRTHNMKDGLIVLEKGKEVIVSMNEVEGTPEKFSVTYENLINDVNIGSYILLDDGLVELQVKEINKDKGEVKCDILNTGELKNKKGVNLPGVKVNLPGITDKDADDIRFGIKENVDFIAASFVRRPSDVLDIRQILEEEKAEITIFPKIENQEGIDNIEEILEVSDGLMVARGDMGVEIPPESVPMVQKDLIRKCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGQYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGVSVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEKTARQCAIVWGVNPVVKEGRKTTDALLNNAVATAVETGRVSNGDLIIITAGVPTGEKGTTNMMKIHLVGDEIAKGQGVGRGSVVGHAIVADSASDLEGKDLSDKVIITNSVDETLVPYVEKAIGLITEENGITSPSAIIGLEKGIPTVVGVEQATKEIKNDMLVTLDASQGKVFEGYANVL
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PEP-utilizing enzyme family.
Protein: YAEP_ECOBW
Sequence: MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALSEAVREKAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein YaeP.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: WAKLA_ARATH
Sequence: MKTKTSIFQFIVASVLTLLINDSSAATPPPPISNSSTSCNKTCGGISIPFPFGIGGKDCYLNGWYEVICNTTTSDSNTTVPLLSMINREVVNISLPDSNEPYGLVQIKGPVTSLGCSSNTSEGPQNSLPVLNVTGKGSPYFLTDENRLVAVGCGIKALMTDTESEILGCESSCEHRKSGEEVTNLICTGYRCCQARLPVGRPQAITVNIENSSGGEETCKVAFLTDKRYSPSNVTEPEQFHNNGYVVLELGWYFATSNSRFKSLLGCTNMSRKGSGFSDDNCSCEYDYFSGMSYRNCYCDYGYTGNPYLRGGCVDTDSCEGNHNCGEDAHCVNMPGPMSMCRPNPKITKPTKPPVLQGILIGLSGLVFFVGLFWLFKLIKKRRNINRSKKFFKRNGGLLLKQQLTTKDGNVEMSKIFSSKELRKATDNFSIDRVLGQGGQGTVYKGMLVDGSIVAVKRSKVVDEDKMEEFINEIVLLSQINHRNIVKLLGCCLETEVPILVYEYIPNGDLFKRLHDESDDYTMTWEVRLRIAIEIAGALTYMHSAASFPIFHRDIKTTNILLDEKYRAKVSDFGTSRSVTLDQTHLTTLVAGTFGYMDPEYFLSSQYTHKSDVYSFGVVLVELITGEKPLSRVRSEEGRGLATHFLEAMKENRVIDIIDIRIKDESKLEQVMAVAKLARKCLNRKGKNRPNMKEVSNELERIRSSPEDLDVRTENEDEEEDQPMAINNKR
What is the function of this protein?
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.
What are the official names of this protein?
Wall-associated receptor kinase-like 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MF6LB_XENLA
Sequence: MSSTKQWDISKALAVATLFHFFHNVGKFCLMPFLTLYFRQLGLGASLVGIIIGFKHAVHLLWAPLCSFLAKSHRKRRFFIMASLLLSAGAGGLFAFYPPLDKNIVSLFCNTSMPWKEQLNPPIDISVFVDENISTTYATPTNHQTTNGEFNTFPSSVAEVAIDTTMASSLDMKTTTHQRFTDQFPSSSPLTRNKRLEHQTRKVLGSGKAQKANSSKSSASNSKQRSSLNNQTAPFATHPNVSHRPSIHERKVRDISIDFTDSFLDPKHKIFLIVLAMVIIWEILAAPLEWIADDSLYEYLDFVDATDRHGKLWIWGYLGASMGSIFITFLIDNLNCFVIFDIPRVSFHFFCYGGFLISTFFLSTLYPVHVSKKTEHSNKTVKALGFLGSDGRIVLTALTVFVLGAVGSTIQNFLFWQMQDIGSNELYMGLSIAAGLLSELALYFFRNKLLKTLTFKWMVVLGLLSLGIQFLYYSFLWTPWSVVAIQILNAFSSGVIWWAINSQVVDVASPGTERSLQLTLRWLAYGCGSSAGSFASGFIISRFSLAVLYQACCITLLTWIVIFLLVQPKLPNIKKINYSRLLAADNSDMSDSDEEQDRDWLVTAMKDENSNRKW
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 6-like protein B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. MFSD6 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FABPL_LEPPA
Sequence: AFSGTWQVYAQENYEAFLKVIGVAEDIIPHAKEIKPTIEIQQSGNSFTVTSTAQKKSTTNTFTIGKEAEITTMNGNKLRCTINMEDGKLVCKTEKFSHIQEVQGEEMIETLTSGSATLIRRSRKV
What is the function of this protein?
Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm.  May be involved in intracellular lipid transport.  Binds one trans-parinaric acid molecule or two cis-parinaric acid molecules.  Affinity for mono- and polyunsaturated fatty acids is higher than that for saturated ones.  Affinity for fatty acid coenzyme A derivatives, lysophosphatidic acid, lysophospholipds, retinoids, bilirubin and bile salts is similar to or higher than that for fatty acids.  Affinity for prostaglandins, peroxisomal proliferators, bezafibrate and clofibrate is moderate to low.
What are the official names of this protein?
Fatty acid-binding protein, liver, Fatty acid-binding protein 1, Liver basic fatty acid-binding protein, Lb-FABP, Liver basic FABP, Liver-type fatty acid-binding protein, L-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_STAES
Sequence: MLISNEWLKDYVNVDQSVQALAERITRTGIEVDDIIDYTKDIKKLVVGHVLSKTPHPNADKLNICQVDLGEEEPVQIVCGAPNVDEGQHVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSHVTPKNYESGIYVFPEAVKPGTDALEAIYLNDQVMEFDLTPNRADALSMVGTAYEVAALYQTKMNKPQLTSNESQESAKDELTIEVKNEDKVPYYSTRVVHDVTIGPSPVWMQFRLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQEQIGSQSIEVRQAKKDETMRTLDGEERRLLDTDIVITNGKDPIALGGVMGGDFSEVTEQTRHVVVEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLERYASGTVLKDRVSHGDLGSFVTPIEITADKVNRTIGFNLTDEEIIDIFEQLGFDTENKNGEITVNVPSRRKDISIKEDLIEEVARIYGYDEIPSTLPVFKDVTSGELTDRQFKTRTVKETLEGAGLDQAITYSLVSKNHATDFALQNRPTIELLMPMSEAHSTLRQSLLPHLIDAVSYNVARKNTNVKLYEIGRVFFGNGEGELPDEVEYLSGILTGDFVNNTWQGKKESVDFYLTKGVVERIAEKLNLQFDFRAGQIDGLHPGRTAIVSLNGKDIGFIGELHPTLAANNDLKRTYVFELNYDAMMEVSVGYINYEPIPRFPGVTRDIALEVNHEVTSSELLSIIHENGEDILNDTLVFDVYEGEHLEKGKKSIAIRLSYLDTENTLTDERVNAVHDKILEALKKHGAIIR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAA10_DANRE
Sequence: MSAALEKPQIIAHIQKSLNYTVFESKWIPCSAKFVCMGNFARGTGVMQIYEIQHGELQLVREIEKSKPIKCGTFGATSLQQRHLATGDFDGNLNVWNLEVPDSPVYSVKAHKEIINAIDGVGGLGIGDGAPEIVTGSRDGTVKVWDSRQKDTPVVNMEPTEGETKRDCWTVAFGHAFNDQDRCVCAGYDNGDIKLFDLRNMSLRWEKNIRNGVCSVEFDRKDINMNKLVATSLEGKFHVFDMRTQHPSKGFASVSEKAHKSTIWQVRHLPQNRDVFMTAGGAGNLHLWKYEYPAQRSKKGADDVEMGVAGSVNLLQNVTLSTQPISSLDWSPDKQGLCVCSSFDQSVRVLIVTKLNTV
What is the function of this protein?
Key assembly factor specifically required for the stability of axonemal dynein heavy chains in cytoplasm.
What are the official names of this protein?
Dynein axonemal assembly factor 10, WD repeat-containing protein 92.
What are the subcellular locations of this protein?
Dynein axonemal particle.
Protein: KDSA_THIDA
Sequence: MKLCHFEAGLDQPLFLISGPCVIESEQLAMDTAGQLKEMCAGLGIPFIYKSSFDKANRSSTKSFRGLGLEEGLRILADVKAKIGVPVLTDVHEDTPLDEVAAVVDVLQTPAFLCRQTNFIQNVARAGRPVNIKKGQFLAPWDMQNVVDKAREVGNDQIMVCERGVSFGYNTLVSDMRGLAIMRGTGCPVVFDATHSVQQPGGQGATSGGQREFVPVLARAAVASGVAGVFAETHPDPACALSDGPNAWPLGMMRELLETLKEIDALVKQRGFIEHKLMKA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPO_RAT
Sequence: MELTDLLLVAILLLTARLTLSSPVPPACDPRLLNKLLRDSYLLHSRLSQCPDVNPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPPQGRTTAHKDPSALFLSLQQLLRGKVRFLLLVEGPALCVRRTLPTTAVPSRTSQLLTLNKFPNRTSGLLETNFSVVARTAGPGLLNRLQGFRAKIIPGQLNQTSGSLDQIPGYLNGTHEPVNGTHGLFAGTSLQTLEAPDVVPGAFNKGSLPLNLQSGLPPIPSLAADGYTLFPPSPTFPTPGSPPQLPPVS
What is the function of this protein?
Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells.  It acts at a late stage of megakaryocyte development.  It may be the major physiological regulator of circulating platelets.
What are the official names of this protein?
Thrombopoietin.
What is the protein family that this protein belongs to?
Belongs to the EPO/TPO family.
What are the subcellular locations of this protein?
Secreted.
Protein: HAOX2_MOUSE
Sequence: MSLLCLADFKAQAQKQLSKTSWDFIEGEADDGITYNDNLAAFRRIRLRPRYLRDVSKIDTRTTIQGQEINAPICISPTAFHSIAWADGEKSTAKAAQKANICYVISSYASYTVEDIVAAAPGGLHWFQLYVQPDWDINKQMVQRIEALGFKALVVTVDAPVLGNRRGNKRSLLDLEANIKLKDLRSPGESKSGLPTPLSMPSSSSCWNDLPLLQSMTRLPIILKGILTKEDAELAVKHNIRGIIVSNHGGRQLDEVPASIDALREVVAAVNGKIEVYMDGGVRTGNDVLKALALGARCIFLGRPIIWGLACKGEDGVKEVLDILKEELHTCMALSGCRSVAEISPDLIQFSRL
What is the function of this protein?
Oxidase that catalyzes the oxidation of medium chain hydroxyacids such as 2-hydroxyoctanoate, to the correspondong 2-oxoacids.  Its role in the oxidation of 2-hydroxy fatty acids may contribute to the general pathway of fatty acid alpha-oxidation.  Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2.  Is not active on glycolate, glyoxylate, L-lactate, 2-hydroxybutanoate and 2-hydroxyhexadecanoate.
What are the official names of this protein?
2-Hydroxyacid oxidase 2, HAOX2, (S)-2-hydroxy-acid oxidase, peroxisomal, Medium chain alpha-hydroxy acid oxidase, Medium-chain L-2-hydroxy acid oxidase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: HEM1_LEGPC
Sequence: MVFVACGLNHKTAPIHVREKVALQPAMQDSLLSSLLDLPEVNEAAILSTCNRTEIYCDTNTPEVLGNWLAHEHQLSEELLSQFLYIHQGKEGIKHTLRVASGLDSMMIGEPQILGQMKQAYQHACRLGTVKTQLRPVFEYIFRASKRIRTRSGIGANPVSIAYAAVQLIGQLFKNYHSLSVFLIGSGETASLVAKYLHQHGVHRFLIASRTLENAQKLAETFGGKTLSIGDIPQYLPLADVVISATACPLPFINKSLVEHALEQRNHAPMFLLDLAVPRDIEGNVNELEQVHLYNVDDLQSMIEKGMNERRNAALQAEQLIESELDNYIRWHRSLRAKDVICDYRNQMHTLAQQELQRALKKISAGQNQQDVLNEFSMRLVNKLTHNPTIGLRQIAWDNREDLLDLARYLFDTTANQSLYEEIS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: IPI1_ORYSJ
Sequence: MGAEEEEEPASAVGREGGGGGGGARAAGAGAGGDTADDDDSGESAAAVVPCSICLDAVVAGGGDRSTARLQCGHEFHLDCIGSAFNAKGVMQCPNCRQIERGNWLYANGSRPSQDVSNDDWGHDEDFYDANQPETSRSVFLPFRFQWCPIGRLAQLPSVFDEGESAPPVTFHDFMGQNFTSEHLPVSAPGATPPGPYIAYFQPLQSSASSSSSHVTERTMDGTTYHDHWNPLPGPSDGRPLATVHPIDFHHNHWTHLPNSYSQPNSNNGVAEQMAIPVVPMRVGGLDSDSQQRGSLPSVYGNGSGSRSRIPSVPPMAPQFMRPHGNINEQYQQNSSSLYAAPQRRTAVQAVQDSMNFTLFPQAPTGPNSMETEDAGGNQFYAWERDRFAPYPLMPVDSEANWWGSTPQSHGVTDHSAAPGRRLFGQWIGAGRSPPPPPPPPADNSSYRQMHIPRM
What is the function of this protein?
Functions as an E3 ligase that promotes polyubiquitination of SPL14/IPA1 for subsequent proteasomal degradation (PubMed:28298520).  Regulates plant architecture by modulating SPL14/IPA1 abundance (PubMed:28298520).  Promotes the degradation of SPL14/IPA1 in panicles, while it stabilizes SPL14/IPA1 in shoot apices (PubMed:28298520).  Ubiquitinates the SPL14/IPA1-mediated complex with 'Lys-48'-linked polyubiquitin in panicles and 'Lys-63'-linked polyubiquitin chains in the shoot apex (PubMed:28298520).
What are the official names of this protein?
E3 ubiquitin-protein ligase IPI1, IPA1-interacting protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALAXL_PYRHO
Sequence: MVERVYYKDPYLREIDAKIVDVRKEKDRVEVVLDRTIFYPEGGGQPGDRGVIKGNDFEIMVEDTIEKNGEIFHIGKLRGEIPKEGEKVKLYLDWEWRYGNMQMHTGQHILSAVLKKLYDLDTTGFNIFRDYAKIEVNGEVNWDMIERAELEVNKIIINDLPVVIEEYDKLPEEIALKLRKNVTKVKEKIRIVKIGDVDVTPCGGTHVKSTREVGIIKVLRFYKKSKNLWRIEFTCGYRAISKMNEILRDYWGSLDLMPNKNPPLIERINEVLRTVNSLENRIEELRREIWEWKGKALLKEGVKVGNYTVITHVENWNMKDAQAFAIDFVKKNSNTILLLANEKYVLFAKNEGVPVSMRELLKEVIDELGGKGGGTDNLARGRVEAKPEEIFDVALEKLRSHLQV
What is the function of this protein?
Functions in trans to edit the amino acid moiety from mischarged charged tRNA(Ala).
What are the official names of this protein?
Alanyl-tRNA editing protein AlaX-L, AlaX-L, Alanyl-tRNA deacylase AlaX-L.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Editing domain AlaX-L subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATB_CHICK
Sequence: MAAVAAARRMVNGAGPGGAREQAAALTRDFLSQPRLTYKTVSGVNGPLVITSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPAVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVMDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFEKNFIAQGPYENRTVYETLDIGWQLLRIFPKEMLKRIPQTTLAEFYPRDSTAKH
What is the function of this protein?
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Essential for the proper assembly and activity of V-ATPase (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit B, V-ATPase subunit B, Vacuolar proton pump subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.