PharMolix/UniProtQA huggingface dataset:
Protein: GUAA_HELPH
Sequence: MILVLDFGSQYTQLIARRLRESGIYAEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPSEKIFDLNVPILGICYGMQYLVDFFGGVVAGANEQEFGKAVLEITQDSVIFEGVKTKSLVWMSHMDKVIELPKGFITLAKSPNSPHCAIENGKIFGLQFHPEVIQSEEGGKILENFALLVCDCEKTWGMQHFAQREIARLKEKIANDKVLCAVSGGVDSTVVATLLYRAIKDNLIAVFVDHGLLRKNEKERVQAMFKDLQIPLNTIDAKGIFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGTLYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEARLLGKELGISQDFLMRHPFPGPGLAVRILGEVSESKIKRLQEADFIFIEELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVSNRITNEVSGINRVVYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: XPP_DROME
Sequence: MKRSTTQILTRLRELMLRAQVGDSCGISAYIVPSDDAHQSEYQCQHDERRSFVSGFDGSAGTAVITTETALLWTDGRYYQQAEKQLDSNWVLMRDGLSATPSIGAWLAKNLPKGSFVGVDPRLLSFRVWKPIETELSSAECQLVPIEGNLIDEVWGEDQPPQTSNKIITLKLEHSGVTIAKKWDVVRQQLKEKNADALVVSALDEIAWFLNLRGSDIDFNPVFFSYLIVTNDELLLFVDSGKLPTDFVQHQKENNVQISVLPYASIGIEISKIVSTRESKIWIAPTSSYYLTALIPKSRRIQEVTPICVLKAIKNDVEIAGFINSHIRDGVALCQYFAWLEDQVNKGAEVDEMSGADKLESFRSTKDKYMGLSFTTISASGPNGSVIHYHPKKETNRKINDKEIYLCDSGAQYLDGTTDVTRTLHFGEPTEFQKEAYTRVLKGQLSFGSTVFPAKVKGQVLDTLARKALWDVGLDYGHGTGHGVGHFLNVHEGPMGVGIRLMPDDPGLQANMFISNEPGFYQDGEFGIRVEDIVQIVPGQVAHNFSNRGALTFKTITMCPKQTKMIKKELLSDAEVKLLNSYHQQVWDTLSPILSREGDEFTLSWLKKEVQPI
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.
What are the official names of this protein?
Xaa-Pro aminopeptidase ApepP, Aminopeptidase P, AP-P.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLBL1_BOVIN
Sequence: MSRHSQDERLGLPQPPALLPLLLLLLAVAVPLSQAGVYYATAYWMPTEKTIQVKNVLDRKGDAYGFYNNSVKTTGWGILEIKAGYGSQSLSNEIIMFAAGFLEGYLTAPHMDDHFTNLYPQLIKKRSMLNKVQDFLTKQDQWTRENIKYYKSDPFWRHADYVMAQMDGLFAGATKRAVLEGKKPMTLFQIQFLNAIGDLLDLIPSLSPTKNSSLKFFKRWDMGHCSALIKVLPGFENIFFAHSSWYTYAAMLRIYKHWDFNIVDKDTSSSRLSFSSYPGFLESLDDFYLLSSGLVLLQTTNSVYNKTLLQHVVPQSLLAWQRVRVASMMANNGKQWAEVFSKYNSGTYNNQYMVLDLKKVNLNHSLDEGTLYIVEQIPTYVEYSEQTAVLRRGYWPSYNIPFHEKVYNWSGYPILVKKLGLDYSYDLASRAKIFRRDQGKVTDMESMKYIMRYNNYKQDPYSKGDPCNTVCCREDLNSHSPSPGGCYDTKVADIYLASKYKAYAISGPTVQGGLPVFHWSRFNKTLHEGMPEAYNFDFITMKPIL
What is the function of this protein?
Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids (By similarity).  However, in view of the small size of the putative binding pocket, it has been proposed that it may act rather as an amidase or a peptidase (PubMed:23934913).
What are the official names of this protein?
Phospholipase B-like 1, LAMA-like protein 1, Lamina ancestor homolog 1, Phospholipase B domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase B-like family.
What are the subcellular locations of this protein?
Lysosome.
Protein: RL1_STRR6
Sequence: MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEVAYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVAKINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQGVGIKVDVNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RS11_PYRIL
Sequence: MSATEQPQQQQQKLRWGIAWIYSSSNNTIITITDLTGAETVARVSGGMVVRADKDKPSPWAAMQAAYKAAQLALARGINAVHIKVRGPGGYGMKVPGPGASAAIRALARSGLIIGRIEDVTPIPHDTIRPPSGRKGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PG003_VACCC
Sequence: MSRINITKKIYCSVFLFLFLFLSYISNYEKVNDEMYEMGEMDEIVSIVRDSMWYIPNVFMDDGKNEGHVSVNNVCHMYFTFFDVDTSSHLFKLVIKHCDLNKRGNSPLHCYTMNTRFNPSVLKILLHHGMRNFDSKDEKGHHYLIHSLSIDNKIFDILTDTIDDFSKSSDLLLCYLRYKFNGSLNYYVLYKGSDPNCADEDELTSLHYYCKHISTFYKSNYYKLSHTKMRAEKRFIYAIIDYGANINAVTHLPSTVYQT
What are the official names of this protein?
Truncated Ankyrin repeat protein OPG003.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG003 family.
Protein: SYR_CELJU
Sequence: MNIRDLLNQRVLAAMATCGVPADLPALIAPGKKAGFGDYQANGAMGAAKAMGTNPRDLAGKIVAALDLEGIADKLEIAGPGFINIYLKPAWLGKQIALAQTDARLAVPQAEHAQTVVIDYSGPNLAKEMHVGHLRSTIIGDSLARLLEFLGHQVIRQNHVGDWGTQFGMLIAELEEQLGAKGDAALELKDLEVFYQQAKKHFDDDAAFADKARDYVVRLQGGDAQMLKLWQQFKDISLHHSSEIYQQLNVTLTDADVRGESFYNDDLAPLVKALQDQGLAVESEGAQVVFLPELADKDGNPSPVIIQKQGGGFLYATTDLAALRYRVNTLNAKRIMYFIDARQSLHMQQVFTISRKAGFVSDAVSLEHLAFGTMMGSDGKPFKTRTGGTVKLAELLSEAVDRAASVVSEKNPELAGEDIAEIARKVGIGAVKYADLCKTRTNDYVFSWESMLSFEGNTAPYLQYAYTRVQSIFRKAGVAPETLGSPILLGSEQEKALAIKLLQFSEVLDQMAREAMPHLLCTYLYDIASLYMSFYEACPILKEGVDAEVRDSRLRLCHLVARTIAQGLGLLGIEVMERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_ECO7I
Sequence: MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_SERP5
Sequence: MPIRKVSLLRLIPLASLVLAACTTTKPTGPATSPTSPQWRAHEQAVQQLSQYQTRGSFAYLSDQKKVYARFFWQQYSPDRYRLLLTNPLGSTELDLNVQKNVVQLTDNQGKRYVSDNAEEMIRKLTGMAIPLDNLRQWMLGLPGEASDFKLDDQYRLNSLTYQQGSQTWTVDYQDYNNSLKPQLPSRLELKQGDQRIKLKMDDWTLK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RL14_SPHAL
Sequence: MIQMQSQLEVADNSGAKRVQCIKVLGGSKRRTAGVGDVIVVSIKEAQPRGKVKKGDVHRAVIVRTAKDVRRADGSVIRFDSNAAVLVNKNEEPIGTRIFGPVVRELRGRGYMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PURNU_XYLFA
Sequence: MGRFPSWVLVADWPAPPGVMVLSTLRGGPGVSVAPFDRLNLGNCSGVAGDAPVCVERNRSRLVEMLGLPSVPHWLRQVHGVEVLRVDALLQSIARVVEPTADAAVTSVVGAVLAILTADCLPVVLAAVDGSEIGVVHAGWRGLADDVLGRTVAALRTSPEYLQAWLGPAAGPQAYEVGVDVYAAFVERDSGAACAFSVTRPGHWYVDLYALARQRLMRAGLSAVSIYGGGLCTISDPQRFFSHRRDRRSGRFATLAWIGC
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine.  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate.  Also has adenosine deaminase activity.
What are the official names of this protein?
Purine nucleoside phosphorylase XF_0940, Adenosine deaminase XF_0940, S-methyl-5'-thioadenosine phosphorylase XF_0940.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: LOLA_YERE8
Sequence: MKKLLVACCLLSGLISAHALADASSDLQARLGKVNSFHANFSQKVTSSEGTAVQEGEGELWVKRPNLFNWHMTSPDESVLISDGETLWFYNPFVEQATATWLKNATGNTPFMLITRNNPDDWKQYNVKQKGDDFELTPKSASGNLKQFAITVTPTGTIKSFTAVEQDGQRSAYTLKGQQNSSADASKFKFTLPKGVTLDDQRQ
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: EPGN_MOUSE
Sequence: MALGVLIAVCLLFKAMKAALSEEAEVIPPSTAQQSNWTFNNTEADYIEEPVALKFSHPCLEDHNSYCINGACAFHHELKQAICRCFTGYTGQRCEHLTLTSYAVDSYEKYIAIGIGVGLLISAFLAVFYCYIRKRCINLKSPYIICSGGSPL
What is the function of this protein?
Promotes the growth of epithelial cells.  May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
What are the official names of this protein?
Epigen, Epithelial mitogen, EPG.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DEF_SHIBS
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RL10_MARSD
Sequence: MNRQEKAQIIEQLKEKAERASIAIVTDFKGLGVEEFTQLRANLRNVGVDCQVVKNTLARLAFTGTDHEVLADKFKENCAIVIGYDDPVAAAKAVADFAKESKTFDMRFASLEGKYLDEDGVKALSKLPSKEELLGKALGTMNAVPTNFVSLLANVPRGFLNVLTALKDQKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: TOP1_VACCW
Sequence: MRALFYKDGKLFTDNNFLNPVSDDNPAYEVLQHVKIPTHLTDVVVYEQTWEEALTRLIFVGSDSKGRRQYFYGKMHVQNRNAKRDRIFVRVYNVMKRINCFINKNIKKSSTDSNYQLAVFMLMETMFFIRFGKMKYLKENETVGLLTLKNKHIEISPDEIVIKFVGKDKVSHEFVVHKSNRLYKPLLKLTDDSSPEEFLFNKLSERKVYECIKQFGIRIKDLRTYGVNYTFLYNFWTNVKSISPLPSPKKLIALTIKQTAEVVGHTPSISKRAYMATTILEMVKDKNFLDVVSKTTFDEFLSIVVDHVKSSTDG
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils.  Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1B, TopIB, DNA topoisomerase I, Late protein H6.
What is the protein family that this protein belongs to?
Belongs to the type IB topoisomerase family.
What are the subcellular locations of this protein?
Virion.
Protein: RPE65_CHICK
Sequence: MYSQVEHPAGGYKKLFETVEELSSPVTAHVTGRIPTWLRGSLLRCGPGLFEVGAEPFYHLFDGQALLHKFDFKEGHVTYHRRFVRTDAYVRAMTEKRIVITEFGTYAYPDPCKNIFSRFFSYFKGVEVTDNALVNVYPVGEDYYACTETNFITKINPDTLETIKQVDLCKYVSVNGATAHPHVENDGTVYNIGNCFGKNFSLAYNIIRIPPLQADKEDPMNKSEVVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLLKFLSSWSLWGANYMDCFESNETMGVWLHVAEKKKGRLLNIKYRTSAFNLFHHINTFEDNGFLIVDLCTWKGFEFVYNYLYLANLRANWDEVKKQAEKAPQPEARRYVLPLRIDKADTGKNLVTLPYTTATATLRSDETVWLEPEVIFSGPRHAFEFPQINYKKYGGKPYTYTYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSIVISPGSGPKPAYLLILNAKDMSEVARAEVEVNIPVTFHGLFKRA
What is the function of this protein?
Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins.  Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore (PubMed:19490105).  Essential for the production of 11-cis retinal for both rod and cone photoreceptors (By similarity).  Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (PubMed:28874556).  The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester.  The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol.  The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT (By similarity).
What are the official names of this protein?
Retinoid isomerohydrolase, All-trans-retinyl-palmitate hydrolase, Lutein isomerase, Meso-zeaxanthin isomerase, Retinal pigment epithelium-specific 65 kDa protein, Retinol isomerase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor. Microsome membrane. Note=Attached to the membrane by a lipid anchor when palmitoylated (membrane form), soluble when unpalmitoylated.
Protein: DADA_CHRSD
Sequence: MQVLILGSGVVGVTSAYYLATQGHEVTVVDRREAPAMETSYGNAGQVSFGFSSPWAAPGIPRKALKWMFQEHAPLKIQPKRDPAMARFMMAMFNNCTPERYAVNKERMVRVAEYSRQCIDALRRDTGIRYEDRQRGLLQLFRHESQVEAAGKDMRVLSECGVRHRLLGAEELVTAEPALARVPGKFVGGLHLPDDQTGDCHLFTQRLAEHCREHLGVTFRFGVDVQRIERQAGRVERVVTSAGSLRADAYVVCLGSFSPLLVKDLDIRLPIYPVKGYSLTLPVTDDGGAPQSTVMDETFKVAISRFDDRIRVGGTAELASYDLSLLEKRRATISMVVRDVFPEGGDAAKAEFWTGLRPMTPDSTPIIGATRYDNLWLNTGHGTLGWTMSCGSAHLLADLMAGRRPAIDPIGLDVSRYAA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: ARH37_MOUSE
Sequence: MADFGADEASSKSESPEQEDQGSEDRSLLHQRLAIRELIDTEVSYLHTLRLCASDIRSHLQQLPPGDLDILFSNIDDIIQVSSRFLRGLQETACREEEQAHLIGNLFLEFQEEFEQVYKVYCANYDQALLLVKAYQKEPELQKEIQGIIEAAMPQAGPSGLSFFLVIPLQRITKYPLLLQKILENTPADASAHPALQRATSALQDVNGNINEYKMRKEVALKYTKVEQLSLRERLARINTHTLSKKTTRLSQMLKQEAGLVSRTEDKEFDDLEERFQWVSLCVKELRNNVVDFMGNLEVFLSFRPHERSLDIPGGPAEQYCSLARDLQLHAFLQFKQRLRSLVWQPLCSLARALAGPQNLIKKRLDKLLDFDRVEEKLLDVGSVTWEEEAARHEYQALNSLLVAELPQFNQLVMQWLGQILCTFVVLQRDLADQVLRRAESTMALLPHHHVSEPDFQKLLEHTLGQSSSQLRLFQESFEKVLPPSTTQPLLPGSEHQMQALLTRYGPEKLYQVSSNINGTGTLDLTLLRGQIVALLQNKDTKGNNSRWLVDTGGHRGYVPAGKLQLYHPIIPSEKELRGQTGTHEDSWLPAPEPTQLSVPTVPTMSQVVAVYPFVARSTHELSLQAGQPVTILEAQDKKGNPEWSLVEANGQRGYVPSNFLARTPSPTPWGWNLPS
What is the function of this protein?
May act as a guanine nucleotide exchange factor (GEF).
What are the official names of this protein?
Rho guanine nucleotide exchange factor 37.
Protein: OR2J2_HUMAN
Sequence: MMIKKNASSEDFFILLGFSNWPQLEVVLFVVILIFYLMTLTGNLFIIILSYVDSHLHTPMYFFLSNLSFLDLCHTTSSIPQLLVNLRGPEKTISYAGCMVQLYFVLALGIAECVLLVVMSYDRYVAVCRPLHYTVLMHPRFCHLLAAASWVIGFTISALHSSFTFWVPLCGHRLVDHFFCEVPALLRLSCVDTHANELTLMVMSSIFVLIPLILILTAYGAIARAVLSMQSTTGLQKVFRTCGAHLMVVSLFFIPVMCMYLQPPSENSPDQGKFIALFYTVVTPSLNPLIYTLRNKHVKGAAKRLLGWEWGK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2J2, Hs6M1-6, Olfactory receptor 6-8, OR6-8, Olfactory receptor OR6-19.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS17_HYPNA
Sequence: MPKRIMKGVVVSAKQDKTAIVRVERTFTHPMLKKIVRKTNKYHAHDENNVAVEGQTIAIRECAPKSKLKRWEVVAEEGTEA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CYB_CYNLE
Sequence: MTNTRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGLCLAIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFVVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFVLPFIIAALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKXILGVLLLILALMILVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYTILRSIPNKLGGVLALVFSILILSLFPLLHVSKQRSMMFRPLSQCMFWFLVADLLTLTWIGGQPVEYPFITIGQLASILYFTIILLMLPIVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YMGG_ECO8A
Sequence: MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNGVNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVIGGTGGAILGKMK
What are the official names of this protein?
UPF0757 protein YmgG.
What is the protein family that this protein belongs to?
Belongs to the UPF0757 family.
Protein: PQQC_XANOR
Sequence: MSALLSPDQLEADLRAIGARLYHDQHPFHALLHHGKLDRGQVQAWALNRFEYQRCIPLKDAAILARMEDPALRRIWRQRIVDHDGNSATDGGIARWLHLTDALGLDRTLVESGRALLPGTRFAVQAYLQFVSEKSLLEAIASSLTELFAPNIIGQRVAGMLKHYDFVSSDALAYFEHRLTEAPRDSDFALDYVKQHADTVEKQALVKAALHFKCSVLWAQLDALHVAYVTPGIVWPDAFVPDRDASRVAA
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: UBIE_COXBU
Sequence: MNETEKSTHFGYQTVPTDQKTDKVKHVFESVAAKYDLMNDLMSLGIHRWWKDFAITQCRLRTGQRILDLAGGTGDLAKRISPLVGDEGEVVIADINAAMLNVGRRRLLDQGIFRNIQFIQADAEKLPFPNNFFDRIVIGFGLRNVTNQLAALQSMHRVIKPGGFVVILEFSKPTLAPLKAVYDAYSFQLLPRLGKLVAKDEESYRYLVESIRMHPDQEALLSKMTDAGFEDCDYHNLSGGIVAVHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: CPNS2_MOUSE
Sequence: MFLAKAILEGADRGLGGALGGLLGGGGQARAGGGNIGGILGGIVNFISEAAAAQYTPEPPPQQQHFTVVEASESEEVRRFRQQFTQLAGPDMEVGATDLMNILNKVLSKHKELKTEGFSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKKWQCVFKQYDSDHSGSLGSSQLHGAMQAAGFQLNEQLYLMIVRRYADEDGGMDFNNFISCLVRLDAMFRAFKALDRDRDGLIQVSIREWLQLTMYS
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.  This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity (By similarity).
What are the official names of this protein?
Calpain small subunit 2, CSS2, Calcium-dependent protease small subunit 2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon calcium binding.
Protein: ACM3_HUMAN
Sequence: MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPLGGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL
What is the function of this protein?
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.  Primary transducing effect is Pi turnover.
What are the official names of this protein?
Muscarinic acetylcholine receptor M3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with TMEM147 in the endoplasmic reticulum (ER) membrane. TMEM147 impairs its trafficking to the cell membrane leading to its retention in the ER membrane.
Protein: EFP_CERSK
Sequence: MKVIASSLRKGNVVDIDGRLYVVLTAQNFHPGKGTPVTQVDMRRISDGTKVSERWKTTEQVERATVDEREYDFLYEDGEGYHFMEPVSYDQVVVSPDVVGDGKVFLTEGMRVYLQTHNDVAISIEFPQKVTVEITETEPVVKGQTASSSYKPAMCTNGLRVMVPPHISAGTRIVINTEDLSYVERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNCJ_ECOLI
Sequence: MFTKALSVVLLTCALFSGQLMAGHKGHEFVWVKNVDHQLRHEADSDELRAVAEESAEGLREHFYWQKSRKPEAGQR
What are the official names of this protein?
Uncharacterized protein YncJ.