PharMolix/UniProtQA huggingface dataset:
Protein: SUCC_AGRVS
Sequence: MNIHEYQAKALLKSFGAPVAEGVAIFSADEAEAAAKQLPGPLYVVKSQIHAGGRGKGKFKELGPDAKGGVRLAFSIDEVKSHVAEMLGNTLVTNQTGPAGKQVNRLYIEDGADIERELYLSLLVDRAVGQVAFVVSTEGGMDIETVAHDTPEKIISVAIDPEAGVTAANLEALTAALLLEGEAKADAEKLFPILYKAFVEKDMALLEVNPLIVMKNGRMRVLDAKMSFDGNALFRHEDVVALRDKTEEDAKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKEKVTAAFKIITADPAVKGILVNIFGGIMKCDVIAEGVLAAVKDVGLTVPLVVRLEGTNVELGKKIINESGLNVISADDLDDAAQKIVAAVKAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: LYSC_CERAT
Sequence: MKAVIILGLVLLSVTVQGKIFERCELARTLKRLGLDGYRGISLANWVCLAKWESDYNTQATNYNPGDQSTDYGIFQINSHYWCNNGKTPGAVNACHISCNALLQDNIADAVTCAKRVVSDPQGIRAWVAWRNHCQNRDVSQYVQGCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: GRPE_RICPR
Sequence: MKDYNIENNNVEEENPNVETQVVDNEEIVRLKAEIEELKDKLIRTTAEIDNTRKRLEKARDEAKDYAIATFAKELLNVSDNLARALAHKPANSDVEVTNIISGVQMTKDELDKIFHKHHIEEIKPAIGSMFDYNLHNAISHIEHPDHEPNSIITLMQSGYKIRDRLLRPAAVQVVKKP
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_METFK
Sequence: MANVSKRIKALRAKVDRNKVYPVTEALALVKETATAKFDESVDAVINLGIDARKSDQLVRGALVLPHGTGKTKRVAVFAQGAAAEAAKAAGADIVGFEDLAEQVKGGMLDFDVAIATPDAMRIVGALGQVLGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQYRTDKGGIVHCTIGRASFEVDALKENLAALVDALNKAKPASSKGVYLKKVSVSSTMGAGVRVDQSNLA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PNP_HELPG
Sequence: MDFITINSSNKTEEFALKQVAKQATSSLMYRLGKTIILASVCVEREPVSEDFLPLVVQFLEKSYAAGKIPGGFVKREGRAQDFEILTSRLIDRTFRPLFPKDYRYPTQITLMVLSHDIENDLQVSALNAASVALFLAHIAPIKSVSACRIARIDDEFIINPNTSLLNQSSLDLFVSGTKESLNMIEMRSLGQKLNALEEPLMLKALELAQKSLKETCTLYEEVFTPHQNELLFKESQGIIFNERLLDLLKNQYFDEIIKGIESSALSERENVFHEIAKKISEAHSEFSLEEIEWSLEKVKKTEIRRMIIQDKIRPDKRALEEVRPILIESDLLPMAHSSILFTRGQTQSLVVGVLGTDNDAQTHESLEHKTPIKERFMFHYNFPPFCVGEASSIGAASRRELGHGNLAKRALETSIKNKEQVIRLVSEILESNGSSSMASVCAGSLALYASGVEIHDLVAGVAMGMVSEGQDYAILSDISGLEDAEGDMDFKIAGNLEGITAMQMDTKMSGIQLEILYQALLQAKEARKHILKIMHEAKEKIVINFSHLPTTEIFNVAPDKIVEIIGQGGRVIKEIVEKFEVKIDLNKPSGEVKIMGNKERVLKTKEFILNYLHSLDQELEQYTIDEVLEAQVKRIVDFGAFLSLPKGGEGLLRKQNMDRCQVVLREGDSIRCRVISFNKGKIALDLA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMB_PHOLL
Sequence: MKNTYNLRSITAKAINQVLDQGQSLSTVLPKLQQNITDKDKPLLQELSFGVLRVLPQLEWIIGQLMVKPLKGKQRILHYLLMVGIYQLAYTRIPAHAALAETVNGAVTLKHSQLKGLINGVLRQFQRQQLQLMECTQNNSSHHLHPEWLLTRIQKAYPQQWQQLINANNKKPPMWLRVNRIYHSRDEYLTLLRKSGIDAEPAPKSPSAIRIISPCPVTILPGFDKGWVTVQDLSAQECVELLKPINGEKILDLCAAPGGKTTYILEIAPESQVVAVDIDEQRIKRVKENLKRLNCHATVKTGDGRHPEHWAENQQFDRILLDAPCSATGVIRRHPDIKWLRREEDIAQLVQLQSEILDAIWPYLKKSGTLVYATCSILPDENCQQISSFLKRHSDAKLAGTETNDCLGKQIIPELNGGDGFFYARLTKR
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_DEIRA
Sequence: MAELISKEGNKVEFKVSVPAAEVNRAYDQVWAGLARDVRVPGFRPGKAPRKVIENRVGKGYVESQVRDRLLETHYSQGLRELGLNLVDATVDPQDVQSGQAFEFTVKGETYPEVKLGDWQGLKVSAQAPEITDEVLEQTLSDLRERNASFEKAERPIEAADQVTIQELGEGDSEEGGSYPIYLDMAEEHVRNALLGKSAGDVVDITVPAHQHGDHEHAEHTVRVKVVEVSSKKLQDLNDEFATSLNYESMDKLRTDLREELERRAQQEGDNLRREELVGHLVEGMTVEIPQALIDRRREGMMSEIQDDLRRQGVQWKEYEAFMQEQGKLDEFEADLTKNAETRVRRDLALEQLATDLNAQVNEAEFNQTLMNLAQANGMNVQQLVQQLGQDGVQSYYISLLRERGLQRALAQLSGEGQSTEAASPKATGTEAAGTEQSEPAQTETAQNDAGQTETAQSEGEQQSE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).  Probably changes conformation upon binding to the ribosome (maybe in particular due to interaction with L24), exposing a hydrophobic crevice that is probably important for its chaperone activity (PubMed:16091460, PubMed:16271892).
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CUP9_YEAST
Sequence: MNYNCEIQNRNSKNVDNQVSLPPIQVLFNSIEKRSMPELAFSNIEYSHGNLRSSTEEQNYPAPVLLPQHHSIAYPAINSGGTSTTATPTASTVETSKTSSSAMDTQSQYGSSKKSKSASDDAKPCYKSAPIYEIINKEKDAGAQYNRPFSDFVESKSRRKQNSGRRSNLPKETVQILNTWLLNHLNNPYPTQQEKRELLIKTGLTKIQLSNWFINVRRRKIFSDYYTLVNSIPNDNANNTPVERVQNVSAYHNTLSATNNTMYDATSTCSTDYELSKRFAHAPVTRRKKLIDRLEELKKLSNPDMN
What is the function of this protein?
Probable DNA-binding protein which plays a role in protecting yeast cells against copper toxicity.  May regulate the expression of important copper homeostatic genes.
What are the official names of this protein?
Homeobox protein CUP9.
What is the protein family that this protein belongs to?
Belongs to the TALE/CUP9 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH10_LIMRJ
Sequence: MLKPLGDRVVLKAETEEEKTVGGIVLASNVKEKPTTGKVIAVGEGRTLENGQKLAPAVKEGDRVLFDKYAGNEVEYNGEKFLVVHAKDLVAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAH_SALSV
Sequence: MATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPGSLDVLRYVKSLGNSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQVDEKKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLEGKGTPEGIYALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGEGEAVNA
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: QUEC_ACTSZ
Sequence: MNISNPNGNRKAVVIFSGGQDSTTCLLQAIRDYGPNNVEAVTFQYGQRHAIELQKAQWIAQDLGVKQTLIDTSVIKTITTNAMMSDAQIKQDENGMPNTFVDGRNALFLLYAAIYAKGQGITDIITGVCETDFSGYPDCRNVFIKSMNVTLNLAMDYQFNIRTPLMYLTKAQTWQLADELGALDYVRQYTHTCYLGVEGGCGTCPSCLLREKGLKQYLAQKSAVEKSSVLTAKEA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: SYM2_CAEEL
Sequence: MNRQTSHPEQRLLLIRVSDGNYDENTKLVVTSFYPRRQEDANNNSTSPSSASSSGSEISTRLVNITPEDVVKFFDEHPTSSYIFTKGPEPIRHVLIPLFARNELCVPHPLHHYYDIKHLYYGNQEEDGMEQEEIEDDVAIARAILDMDDELLEKTHQFVNIEYQPAPILEDQEVGADGDNVVCRARGLPWQASDHHVAQFFAGLDIVPGGIALCLSSEGRRNGEVLVQFSSQESRDLALKRHRNFLLSRYIEVYKAGLDEFMHVATGSSTEAMEFVSANAIIVRMRGLPYDCTDAQIRTFFEPLKLTDKILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEEKKKDCVRLRGLPYEATVQHIVTFLGDFATMVKFQGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSVGKKKRYIEVFQASAEELNLHHLVGQQHQVPPPAPLGFMGQLPPQAPQPQQFWSSYPSPPISPIVPGQVTQLIIYGIHMSIGVPELVANFTTPEHTVDNVLFTRWPTHLCPGEAILTLRNRGAPPPQTSPLSQISQLSAPNFAAYSHHPQNFPLQPILME
What is the function of this protein?
mRNA splicing factor that regulates alternative splicing of many genes in embryo.  Probably plays a role in the formation of embryo-specific isoforms.
What are the official names of this protein?
RNA-binding protein sym-2, Synthetic lethal with mec-8 protein 2.
What is the protein family that this protein belongs to?
Belongs to the ESRP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPPH_SHEON
Sequence: MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGLRPEHVTVLTSTRSWLRYRLPKRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQTQEIPKKRVRQKTTG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: PYRB_BURCJ
Sequence: MTTDTTGRTGNPAAAASPDRFRYGFLKGNPQLTKNGELKHLLSIEGLPRSIVNHILDTAEQFVSVTDREVKKVPLLRGKSVFNLFFENSTRTRTTFEIAATRLSADVLNLNINASSTSKGESLLDTINNLSAMHADLFVVRHASSGAPYLIAEHCAPHVHVINAGDGRHAHPTQGLLDMYTIRHYKRDFTKLRVAIVGDILHSRVARSDIHALTTLGVPEVRAIGPRTLLPGGLEQMGVKVFHNLDEGLKGVDVIIMLRLQNERMSGALLPSAQEYFKTWGLTPERLALAAPDAIVMHPGPMNRGVEIDSQVADGPQSVILNQVTFGIAVRMAVMGIVAGNSD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ARGB_BACAH
Sequence: MNDYIVVKCGGSMLDQLNDVFFDCIKKLQQQYKVVIVHGGGPEIDAKLKDCNINVEKRDGLRVTPKEVMDVVQMVLCGSTNKKLVMNLQKHNLLAVGCSGCDGNLLQVQPVSGEIGYVGEVSYVETALLKGLINMNYIPVIAPVGINDNEIYNINADTAAAGIAAALSAKELIFITDVDGVLHEGKLVKKTDESEIATFIEKGVITGGMIPKVQAALASLKMGVQKISIVNGTKDFTEVTGECIGTTVTKGVSIV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_ALKEH
Sequence: MDLTPREKDKLLLFTAGLLAERRKAKGLKLNHPEAVALISCAIMEGAREGRSVAEMMDAGGQVLTREDVMEGVAEMIPEVQVEATFPDGVKLVTVHEPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_WOLTR
Sequence: MSYIQILPETFSIISSLVLLLLGIVFNRRTINLLALGCTVITLIILILSAKDSGFFPFNSLLKLDLYIRSAQGLILIAGILVLLLLNLSKYDYEYEFSILILFTLFGMITLVSANNLISFYLSFELMSIPLYVLASFNKDSVYSCEAGVKYFTLSALSSCIMLYGMSLLYGYTGLVNFSELSSFLENHQMTYGIVFGLVLILIGLCFKLAIAPFHMWAPDVYQGAPTIVTAFFSTVPKAALVTFLIRFFMGEELVGVEKYFQPVLLYISALSVLISAFGALRQRNLKRLLAYSSIGHIGFILASLSIFTRMGTDSSLIYLVIYIITNIGLFSYFIQIDDDDCSVANLSGIGKKRPVLAFHLSILLFSMAGIPPLAGFFAKLFIFKSLVNSGFIGMSLIFIVASVISCYYYLSIIKAMYFDKPSDSKVIYSKSLFIVTSVASLINIVLFMCVEDLYSLIHLVTKSL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRAF6_BOVIN
Sequence: MSLLHCENSCGSSQSESDCCAAMAASSCGTAAKDDSVSGTASTVTLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEEHQAHCEFALMSCPQCQRPFQKCHLNIHILKECPRRQVPCENCAVSMAFEDKEIHEQNCPLANVICEYCNTMLIREQMPNHYDLDCPTAPVPCTFSAFGCHEKMQRNHLARHLQENTQSHMRMMAQAVQTLSLAVAPVPQCTMPLYDSVPPTRPSSGRHSEVHNFQETIQQLEGRLVRQDHQIRELTAKMETQSMYVNELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPSAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAAVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDSGI
What is the function of this protein?
E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2.  Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation.  Leads to the activation of NF-kappa-B and JUN (By similarity).  Seems to also play a role in dendritic cells (DCs) maturation and/or activation (By similarity).  Represses c-Myb-mediated transactivation, in B-lymphocytes.  Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor (By similarity).  Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation.  Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production (By similarity).  Participates also in the TCR signaling by ubiquitinating LAT (By similarity).
What are the official names of this protein?
TNF receptor-associated factor 6, E3 ubiquitin-protein ligase TRAF6, RING-type E3 ubiquitin transferase TRAF6.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Nucleus. Lipid droplet. Note=RSAD2/viperin recruits it to the lipid droplet.
Protein: VPC42_MYCTU
Sequence: MIVDTSAIVAIVSGESGAQVLKEALERSPNSRMSAPNYVELCAIMQRRDRPEISRLVDRLLDDYGIQVEAVDADQARVAAQAYRDYGRGSGHPARLNLGDTYSYALAQVTGEPLLFRGDDFTHTDIRPACT
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its cognate antitoxin is VapB42 (By similarity).
What are the official names of this protein?
Ribonuclease VapC42, RNase VapC42, Toxin VapC42.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: HISZ_PSEPG
Sequence: MATVDRWLLPDGIEEVLPPEAARIEIARRQVLDLFQSWGYELVVTPHIEYLESLLTGAGQDLDQRTFKVVDPQSGRLMGFRADFTPQVARIDAHTLRREGPSRLCYAGSVLHAQPRALSTSRSPIQLGAELYGDASPTSDVEVISLMLATLQLTDVPDVHMDLGHVGIYRGLARAAGLSGAVEQQLFDALQRKAVDEVQALTADLPKDLGNMLRALVELCGGREVLADARVRLGRAPASVLAALDDLLAIADRLASRYPDLPLYFDLGELRGYNYHTGVVFAVFVPGEGQSIAQGGRYDDIGADFGRARPATGFSTDLKTLVTLGRAEVVLPTGGIWMPDSGDAALWQQVCQLRNEGQRVVQALPGQPLSAALEADCDRQLIQQDGRWQVLLLAQ
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_MYCA9
Sequence: MRVLVQRVVSAAVSVDGEVVGAIRPDGQGLLALVGVTHDDDAEKAAQLAEKMWQLRILDDEKSAADVGAPILVVSQFTLYANTKKGRRPAWNAAAPGGVAEPIVHAFADALRKLGARVEAGVFGAHMRVELVNDGPVTVLLEL
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_ECOSE
Sequence: MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAREILAEVYNGDAPA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: AFP5_MALPA
Sequence: ITCGQVTSQVAGCLSYLQRGGAPAPXXXXGIRNLXXMA
What is the function of this protein?
Possesses potent antifungal activity against F. graminearum but not P. infestans.
What are the official names of this protein?
Antifungal protein 5, CW-5.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: MEL5_YEASX
Sequence: MFAFYFLTACTTLKGVFGVSPSYNGLGLTPQMGWDSWNTFACDVSEQLLLDTADRISDLGLKDMGYKYVILDDCWSSGRDSDGFLVADKHKFPNGMGHVADHLHNNSFLFGMYSSAGEYTCAGYPGSLGREEEDAQFFANNRVDYLKYDNCYNKGQFGTPDVSYHRYKAMSDALNKTGRPIFYSLCNWGQDLTFYWGSGIANSWRMSGDITAEFTRPDSRCPCDGDEYDCKYAGFHCSIMNILNKAAPMGQNAGVGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLIIGADVNHLKASSYSIYSQASVIAINQDPKGIPATRVWRYYVSDTDEYGQGEIQMWSGPLDNGDQVVALLNGGSVARPMNTTLEEIFFDSNLGSKELTSTWDIYDLWANRVDNSTASAILEQNKAATGILYNATEQSYKDGLSKNDTRLFGQKIGSLSPNAILNTTVPAHGIAFYRLRPSA
What are the official names of this protein?
Alpha-galactosidase 5, Alpha-D-galactoside galactohydrolase 5, Melibiase 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ANC2_CAEEL
Sequence: MSIFDRMTTSKEAAMKYRQFCVSKKKEVWDALIYHAKYAKNIEKVYDMTTVLQRVQQECLMFALEKGVGQPDIRDAAELIFPLAMQKVVIKVLRPYFMSHFTNYRLAMYLPHRKIDHGIDLNQELWTPEKKEICGQYVQDFNPFVNELKTGILNANRHMNAALSVYIRELAATLVMHEKAAFDNELRCSMFQEIMESLRIWSDQVTMQDAFHLISDTIYKDVFQMLSKNAYEMIAVDFPVKFRSLITMKYCLLRTNNHGRVDFTNYLIDQVNTKLLVASVDTKDILKAYAACVESLREMDNSCVVMHKVCGVIREYLKRRPDTVQQIISYITSNKKNELEKDMSLQSKTVRSAMMDEEELKGVNDDFLPENMETLGWENWMPNPTDATVGDGAPGHQGVDVFNMLVSVYGSKELFVKEYRNLLAERLSSSDNKDPEFEKRYLDLLKLRFQYSELQHCEVMLRDVIHSLDIDKKFEDMSERSAGNYDVPIIPISACIISSHYWPKLETEKTEALMPQPLQAAMDVYQETYLDVKRDRKLEWLRSVGCVEVSINIDGVEVDRTIPNMYALLLFLFLEKETWTTAEVVEKMGMSVVVTRKRLEWLVKQGFICMNPIISSDTWTLTRNPSGISIVRPGTPDLEDDEDVEPEENSDMVDALEQYWGYTRNFIANHAPNGEVKAERMHRVYRMFGSPTSAGPTLDHVSAFLQRKVALGLLTCINGSYRIIQEKKDGE
What is the function of this protein?
Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins.  Developmental role in early embryogenesis and the metaphase to anaphase transition in meiosis and mitosis.
What are the official names of this protein?
Anaphase-promoting complex subunit 2, APC2, Cyclosome subunit 2.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: MLRA_HUMAN
Sequence: MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
What are the official names of this protein?
Myosin regulatory light chain 2, atrial isoform, MLC-2a, MLC2a, Myosin light chain 2a, Myosin regulatory light chain 7.
Protein: RS21_XANOP
Sequence: MPSVKVRENEPFEFALRRFKRTCEKAGVLAETRKREFYEKPTQERKRKAAAAVKRQLRRSSRDVTKRQRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: SYR_SYNP2
Sequence: MKSILSQLKTAVSEALIKAFGEDLKDTDPLVVPASNPKFGDYQSNVALSLTKILKKNPREIAQSIIEALDIADTCENPTIAGPGFINFSLKPSYLATLLKEVQQSDRLAIEPAENPQKVIVDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGQDVLRLNHVGDWGTQFGMLITYLKEVYPDALTKADALDIGDLVAFYKKAKVRFDEDEAFKEASRNQVVKLQSGDEESQKAWQLLCEQSRREFQKIYDILDIKLTERGESFYNPYLADVLTALDEVGLLEEDAGAQCVFLEGFKNKDGDRLPLIVQKSDGGFNYATTDLAAIRYRIKEDQAKRIIYVTDSGQAGHFAQVFQVAERAGFLPDDVEVVHVPFGLVQGEDGKKLKTRAGDTIKLKDLLDEAVNRSRADLEKRLAEDERQETADFIEKVSQVVGIGAVKYADLSQNRTSNYIFSFDKMLALQGNTAPYMLYAYVRVQGVSRQGGIDLSTLPTDTPIILEEAAELTLAKHLLQLSEVLMSVEQDLMPNRLCEYLYDLSRKFNQFYEACPILKAEGDRRISRLILADTTARTLKLGLSLLGIEVLDRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.