PharMolix/UniProtQA huggingface dataset:
Protein: SYD_LISMO
Sequence: MEKRTSYCGELNEAHIGQSVVLHGWVQKRRDLGGLIFIDLRDREGIVQVVFNPEFSKEALEIADSVRNEFVVTIKGTVHARGEKAINEKLATGKVEVLAEEITILNTSKTPPFYIEDGVNVSDELRLKYRYLDLRRPEMNNIFKMRHTVTRTFRNKLDALGFFDIETPYLTKSTPEGARDYLVPSRVYPGNFYALPQSPQILKQLLMTAGFDKYYQIVRCFRDEDLRGDRQPEFTQIDLETSFLTKEEIQAITEDMLVDVVKEAKNITIEKPFPRMTYKEAMDRFGSDKPDIRFGLELQNVSDVVKDVDFKVFQSAIENGGEVKAINAKAAAANFSRKDLDALGVFVANYGAKGLAWLKVEAGELKGPIAKFFPEDKAAELKVALQAEDGDLLLFAADKADIVAASLGALRNKLGKDLNLINEEELAFLWVTDWPLFEYDEEAERYVSAHHPFTLPKEEDIPLLETDSSKVMAEAYDIVLNGYEIGGGSLRIYKKEVQESMFRALGFTDESAKEQFGFLMDALEYGTPPHGGIALGLDRIVMILAGRNNLRDTIAFPKTGSAVDPLTNAPGEVSEAQLAELKLETVKKETN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6E_METS5
Sequence: MADFKIVISDPASKKVVPAKVKVKLVDNVQSEEGEKEGRTLPVCLVNPKTKEKLGADQFITVEIQKQEGDKKVKVKVHFIARESAEVPEGEIHASKGLTEKFGAEEFEAVAYRTKSFQLNVDQGQVNLVGSKIGDNFTLSVGGIALNLAITGGSDNTGFPMRPDVQGAAKRRILLAGPPGFIPTEDGERRRKIVRGNVISAENVQINCVIVR
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: K1C19_HUMAN
Sequence: MTSYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASKVL
What is the function of this protein?
Involved in the organization of myofibers.  Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
What are the official names of this protein?
Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: GAG_SIVVT
Sequence: MGAATSALNRRQLDQFEKIRLRPNGKKKYQIKHLIWAGKEMERFGLHERLLETEEGCKRIIEVLYPLEPTGSEGLKSLFNLVCVLYCLHKEQKVKDTEEAVATVRQHCHLVEKEKSATETSSGQKKNDKGIAAPPGCSQNFPAQQQGNAWVHVPLSPRTLNAWVKAVEEKKFGAEIVPMFQALSEGCTPYDINQMLNVLGDHQGALQIVKEIINEEAAQWDVTHPLPAGPLPAGQLRDPRGSDIAGTTSSVQEQLEWIYTANPRVDVGAIYRRWIILGLQKCVKMYNPVSVLDIRQGPKEPFKDYVDRFYKAIRAEQASGEVKQWMTESLLIQNANPDCKVILKGLGMHPTLEEMLTACQGVGGPSYKAKVMAEMMQTMQNQNMVQQGGPKRQRPPLRCYNCGKFGHMQRQCPEPRKTKCLKCGKLGHLAKDCRGQVNFLGYGRWMGAKPRNFPAATLGAEPSAPPPPSGTTPYDPAKKLLQQYAEKGKQLREQKRNPPAMNPDWTEGYSLNSLFGEDQ
What is the function of this protein?
p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Matrix protein p17]: Virion. Host nucleus. Host cytoplasm. Note=Following virus entry, the nuclear localization signal (NLS) of the matrix protein participates with Vpr to the nuclear localization of the viral genome. During virus production, the nuclear export activity of the matrix protein counteracts the NLS to maintain the Gag and Gag-Pol polyproteins in the cytoplasm, thereby directing unspliced RNA to the plasma membrane (By similarity). SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: MUTS_SYNJB
Sequence: MDPALLTPMMQHYVELKRQYPHAILLYRLGDFYEMFFQDAQRVSRELELVLTGREAGAIGRVPMCGIPYHAFDRYAAQLVAKGYALAVCDQMEPADQAKGLVRREVTRVITPGTVLEEELLQARQNNYLAAVVRLKGSKQAPCRWGLAYADISTGEFWVCQSEGQEQLEQELARLQPAEVLLPTEEGLGLGLIRPGDPQKPLGLPNQYAYTLRPAEPFELAVARENLMQTYGLRSLEGLGCEGLPLAVRAAGGLLHYLEETHSPQRCVAPKTLLQPSPQGGHPLLPPPRTYQLTDYLILDAQTRRNLELTQTIREGAFVGSLLWVLDHSRTAMGGRTLRRWLLQPLRDSEQIRLRQDTIQELLENPSLRARLGSLLDSLYDLERLANRVGSGTANPRELVALGSSLGKLPQLAELVGEAKTPLLQSLQQVDPALVDLGRRIEHTLLPSPPPILTEGGLIRPGVDPELDRLRQQVEQDRQWVAQLEKSERDRTGIPTLKVGFNKAFGYYLSISRAKAHQVPKEYIRKQTLTNEERFITPELKEKEARILTAQTDINQREYELFVQLRQEAGSRAEAIRQVAQTLAAVDALFGLAEVAVQQGYTRPLLTTDRRLIIEEGRHPVVEKSLPQGLFVPNSVQLGSPHGPDLIVLTGPNMSGKSTYLRQIGLIQILAQMGSFVPARRAELGLCDRVFTRIGAVDDLATGQSTFMVEMNETANILNHAGERSLVLLDEIGRGTATFDGLSIAWAVAEYLATQVRARTVFATHYHELNQLETLLPNVANFQVVVKELQDRIIFLHQVQPGGADRSYGIEVGRMAGLPQPVIQRAEQVLALVEKHSRIGLGLRNQGKSQPAQKNCKKEPAPNRSPDPAVGDQLSLIPAPLFPD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL21_CLOK1
Sequence: MYAVVATGGKQYKVSEGDIIYVEKLEAEVDSTIELDKVLMINKDEGLVVGKPVVEGAKVKAKVLKQGKAKKIIVFKYKPKKDYRKKQGHRQPYTKLQIEKIDA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL29_RHOPT
Sequence: MAEMKTADIRAMSEDQMDDAILSLKKERFNLRFQRATGQLENTSRLREARRDIARIKTIAAQKRAGKTK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: KGUA_HELPH
Sequence: MHNDFNLLILSGPSGAGKSTLTKYLQEKIPKTHFSLSTTTRKPREGEVDGLHYNFVSEEEFKQGIEKGQFLEWAIVHNHYYGTSKIPVEKALKEGKIVIFDIDVQGHEILKKHYPNACSVFISTKNQEILKERLLLRGTDSKETIEKRLINAYKEMQCLESFDYLIINEDLEKSKEIILSIAKTLVHRLKAFNFEKICKAWKNESL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLA25_ARATH
Sequence: MKVVAAYLLAKLSGNENPSVADLKKIVESVGAEIDQEKIDLFFSLIKDRDVTELIAVGREKMAALSSGGGAVAVASGGGGGAAPAAEPASVESKKKEEEKEESEDDGGMMSLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2-5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: HRCA_CAUVN
Sequence: MTQLFPGPIVRTPGLAELDARARDIFRRVVESYLETGEPVGSRTISKGGVALSPASIRNTMQDLAQLGLLDAPHTSAGRMPTHAGLRMFVDGFLEVGDVAEQEKRAIEARLAVKGRSFEEALAEASSILSGLAGGAGIVVTPVREGGVKHVEFVPLGGGQVLAVMVFEDGQVENRLMRQAPGVTPSALQEASNFLNARLRGRTLTEARTEMGGELDAARRQLNETAARLVEDGLAAWSGGEGDARSLIVRGQANLLADARAREDIDRVRQLFDDLEQKGQLIGLLDDVRDAEGVRIYIGAETRLFSLSGSSVIAAPYMTGRQKVLGAIGVIGPARLNYARVIPLVDYTARVLGRMMDG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: SPEH_CLOK5
Sequence: MNELGRHILAEIYGCDGEILNNKDFIEKIMVDSALKAGAEVREVAFHKFSPQGISGVVIISESHLTIHTWPELGYAAVDVFTCGDRINPWDACNYMTEKFNAKNMTATEIKRGIFEQVVEVKASNI
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: SNX16_MOUSE
Sequence: MATPYVPVPMPIGNSASSFTNNRNQRSSSFGSVSTSSTSSKGQLEDSAVGSLKQTNVQDQMDSASSMCGSPLIRTKFTGTDSSIEYSARPREAEEQHPEAVNWEDRPSTPTILGYEVMEERAKFTVYKILVKKSPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNAEFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYHLQRELLEKQKEVESLKKLLGEKQLHIDALETRIRTLSLEPGASLYVSRAEGGQILRVEPSVLQVNRDVLDEESRADHKPHFNSREAGSVIAGIEVAQLAYNAEDD
What is the function of this protein?
May be involved in several stages of intracellular trafficking.  Plays a role in protein transport from early to late endosomes.  Plays a role in protein transport to the lysosome.  Promotes degradation of EGFR after EGF signaling (By similarity).
What are the official names of this protein?
Sorting nexin-16.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Lysosome.
Protein: CECC_DROSI
Sequence: MNFYKIFVFVALILAISIGQSEAGWLKKLGKRIERIGQHTRDATIQGLGIAQQAANVAATARG
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-C.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NANK_VIBVU
Sequence: MKVLAIDIGGTKIALGNVVEGHLQHRKQFPTPVVNDATTLAKEILAHCQAWLSDVDAIGISTTGLVSEQGISAINPGTLSFPTPFPLHSELHRLSGKPVKMLNDAQAAAWYEFLQLSPELDVRNMAYITVSTGVGGGLVINQQLHKGKSNFAGHIGHTVLDPNGPLCGCQQRGCVEAIASGNAINAGAQALFGQAISNIELFQLAQHNEQASTLIQQSAEAIAQLCLNLKATLDLDLVVIGGGVGLARGYLARVQAFIDKQPLVFQVKVRAAVGDYDACLLGAAFQFEESNLS
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: ATPA_ALKMQ
Sequence: MNLRPEEISSIIQEQIKRYENKLEVKDVGTVIQVGDAIARIHGLEKCMAGELLEFPGGVYGMALNLEEDNVGCVLLGSDDKIKEGDTVKRTGRIVEVPVGEALLGRVVNSLGQPIDGKGPIQTDKYRDIERVAPGIIARKSVHEPLQTGIKAIDSMIPIGRGQRELIIGDRQTGKTAIAIDTIINQKHSDVICIYVAIGQKKSTVSQIQDTLEKNGAMEYTIIVASTASELAPLQYIAPYAGCAMGEEFMENGKHVLIIYDDLSKHAVAYRAMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDERGGGSLTALPLIETQAGDVSAYIPTNVISITDGQIFLESELFYSGVRPAVNPGISVSRVGGNAQIKAMKKVAGTLRLELAQYRELAAFAQFGSELDKETQARLAQGERIIEMLKQPQFKPMPVEEQVMMIYAITNKYLTDIEVVEIGPFESQFISYMVGHHAEVGQAIRDNGVLDQASETTLKEAIEAFKKQFKAERE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RLME_BRASB
Sequence: MAKDTTGRMHVQVKTGGKRKLSSKLWLERQLNDPYVAQAKRDGYRSRATYKLIEIDDKYHLLKPGMTVVDLGAAPGGWSQIAARRVGAEAGKGKVIAIDLLEMGEVPGVTFTQMDFHAQDAPEKLRAMLGGRADVVMSDMAANTTGHRKTDQLRIVGLVELAAHFAGEVLKPGGSFLAKTFQSGADAELLAQLKRDYATVRHVKPAASRQDSSERYVLAMGFRGGEPAELL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCBD2_RAT
Sequence: MASRAPLRAARSPQDPGGRAAPAATGRAPLPSAGWCPLPPGRNSSSRPRLLLLLLLLLPDAGAQKGDGCGHTVLGPESGTLTSINYPHTYPNSTVCKWEIRVKTGERIRIKFGDFDIEDSDYCHLNYLKIFNGIGVSRTEIGKYCGLGLQMNQSIESKGSEITVLFMSGIHASGRGFLASYSVIDKQDLITCLDTVSNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGIHAGVVSDVLGGQISVVISKGTPYYESSLANNVTSMVGYLSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHMGQENSWKPEKARLRKPGPPWAAFATDEHQWLQIDLNKEKKITGIVTTGSTLIEHNYYVSAYRVLYSDDGQKWTVYREPGAAQDKIFQGNKDYHKDVRNNFLPPIIARFIRVNPVQWQQKIAMKVELLGCQFTLKGRLPKLTQPPPPRNSNNLKNTTVHPKLGRAPKFTQALQPRSRNDLPLLPAQTTATPDVKNTTVTPSVTKDVALAAVLVPVLVMALTTLILILVCAWHWRNRKKKAEGTYDLPHWDRAGWWKGVKQLLPAKSVEHEETPVRYSNSEVSHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEASYADLDPYNAPVQEVYHAYAEPLPVTGPEYATPIVMDMSGHSTASVGLPSTSTFRTAGNQPPALVGTYNTLLSRTDSCSSGQAQYDTPKGGKPAAAPEELVYQVPQSTQEASGAGRDEKFDAFKETL
What are the official names of this protein?
Discoidin, CUB and LCCL domain-containing protein 2, Endothelial and smooth muscle cell-derived neuropilin-like protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TVB63_HUMAN
Sequence: MSLGLLCCGAFSLLWAGPVNAGVTQTPKFRVLKTGQSMTLLCAQDMNHEYMYWYRQDPGMGLRLIHYSVGEGTTAKGEVPDGYNVSRLKKQNFLLGLESAAPSQTSVYFCASSY
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 6-3.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PYRC_STRT2
Sequence: MLLIKNGRVVDPKSGLDTQADVLVDGKKVVKIAENIDAGDAQVIDATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTNPTISDKETLKEVLTSAAKENIHIKSVATITKNFDGENITDFKGLLEAGAVGFSDDGIPLTNAGIVKKAMELAKENNTFISLHEEDPDLNGVLGFNENIAKKEFHICGATGVAEYSMIARDVMVAYDTQAHVHIQHLSKAESVKVVEFAQKLGAQVTAEVAPQHFSKTEDLLLSKGANAKMNPPLRLESDRQAVIEGLKSGVISVIATDHAPHHADEKNVADVTKAPSGMTGLETSLSLGLTYLVEAGHLSLTELLKLMTSNPSDLYGFDAGYLAENGPADLVIFADKEKRQVTADFKSKAANSPFVGEELTGSVKYTICDGEIVYQV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: Y354_RICCN
Sequence: MTLYYIGILLVIIGLFAIFSGIIGFFRFPDFYTKLHAASVIESFGVPICLIGFACIAADIVNSVKLILAALLIFILNPVATHALGKASLFMKIRADSTVIARKITK
What are the official names of this protein?
UPF0091 protein RC0354.
What is the protein family that this protein belongs to?
Belongs to the UPF0091 family.
Protein: WHITE_DROME
Sequence: MGQEDQELLIRGGSKHPSAEHLNNGDSGAASQSCINQGFGQAKNYGTLLPPSPPEDSGSGSGQLAENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNERHIPAPRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVLAVVPGREIESRDRIAKICDNFAISKVARDMEQLLATKNLEKPLEQPENGYTYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIFLFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKWLSYLSWFRYANEGLLINQWADVEPGEISCTSSNTTCPSSGKVILETLNFSAADLPLDYVGLAILIVSFRVLAYLALRLRARRKE
What is the function of this protein?
ATP-dependent transporter of the ATP-binding cassette (ABC) family which transports various molecules including bioamines, neurotransmitters, metabolic intermediates and second messengers (PubMed:812484, PubMed:117796, PubMed:6788034, PubMed:10407069, PubMed:18310115, PubMed:18931318, PubMed:33820991).  In the eye, required for the transport of the eye red and brown pigment precursors, guanine and tryptophan, into pigment cell granules (PubMed:10407069, PubMed:8144619).  Probably in association with bw/brown, involved in the transport of guanine (PubMed:117796).  Probably in association with st/scarlet involved in the transport of kynurenine and probably tryptophan (PubMed:812484).  Involved in the transport of kynurenine in pupal eyes (PubMed:812484).  May play a role in histamine uptake by the lamina epithelial glia which surrounds photoreceptors R1-R6 (PubMed:18931318).  In Malpighian tubules, involved in the transport of cGMP, guanine, xanthine, riboflavin, kynurenine and tryptophan (PubMed:812484, PubMed:117796, PubMed:6788034, PubMed:18310115).  Probably in association with br/brown, involved in aging-induced intestinal stem cell proliferation in the midgut by regulating tetrahydrofolate transport (PubMed:33820991).  Probably in association with st/scarlet, plays a role in zinc storage granule biogenesis in Malpighian tubule principal epithelial cells (PubMed:29367274).
What are the official names of this protein?
Protein white, ATP-binding cassette transporter sub-family G member white, Broad substrate specificity ATP-binding cassette transporter white.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Co-localizes with st/scarlet to pigment granules within pigment cells and retinula cells of the compound eye.
Protein: SHDAG_HDVV1
Sequence: MSQPGARPGSKXREEALEQWVEERKKKRIAEKELRRINKKIKKLEDENPWLGNIVGLLRRKKDEEGGPPAKRPRREDMEIDSTPGRKSKTRGFTDQERRDHRRRKALENKKKQLAGGGKNLSREEEEELRRLARDDDERERRVAGPRPGGVNPMDGPPRGAPGGGFVPSLQGVPESPFSRTGEGIDIRGTQQFP
What is the function of this protein?
Promotes both transcription and replication of genomic RNA.  Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA.  RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome (By similarity).
What are the official names of this protein?
Small delta antigen, S-HDAg, p24.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: GATA_MAGMM
Sequence: MALNELTLREAADKLATKEISSVELTQACLDQIAKHNPTINAFVTVDAEKALAAAQAADARIAAGNGAPLTGIPIAHKDIFNTTDMRTTCSSRMLENFIPPFDATITTHLRQAGAVILGKTNLDEFAMGSSTETSYFGASRNPWDTQRTPGGSSGGSSAAIAANMAICATGTDTGGSIRQPASLTNLTGLKPTYGRCSRYGIIAFASSLDQAGPMTRTAEDAAMLLNVMVSYDPKDSTSIQSPAPDFTQALTGDVKGLKIGIAAEYFGDGLNDEVRAAIETAQQQYQAMGAELVPISLPNSGYAIPTYYIISPAECSSNLARYDGVKFGYRCEEPKDIRDLYFRSRSEGFGDEVKRRIMLGTYVLSSGYYDAYYRKAQQARRLIADEFKAAFEKVDLILTPTSPTTAFKFGEKDDPVQMYLSDIYTINVNLAGLPGISVPCGFDSKGLPIGMQLIGRPLDEETLLRSADAYQRQTDWHKRRVHLG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: NU4LM_TARRO
Sequence: MTPLNINLTMAFFLALAGVLIYRSHLMSTLLCLEGMMLSLFILLSLLISHFHMLSSSMAPLILLVFSACEAGVGLALLVKMSSNYGNDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MNMA_CARHZ
Sequence: MDVIGRKKVLVAMSGGVDSSVTAALLLEQGYEVVGVTMQIWDPKIEVIGEEYVGCCSIYAVNDARRVADRLGIPYYVLNFRELFERKVIDYFTEEYLRGRTPNPCIACNRYIKFDALLKKALSLGMDYMATGHYARVVYKDDIGKYGLFRGVDRKKDQTYVLYNLTQDMLRRLLLPLGEYTKEQVRELARKYNLVTADKPESQEICFVPDNDYRKFLKERRGEEIKPGNFVDVNGRVLGQHQGYPYYTIGQRKGLGLALGKPYYVVDIRPETNEVVIGEASEIFSPGLIASDLNFLWFDEIPERFEAQAQIRYNAKPQPAVVERIGKDKVKVVFNEPQRAITPGQAVVFYRGDELLGGGTIEKRL
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OX26_HUMAN
Sequence: MVRPYPLIYFLFLPLGACFPLLDRREPTDAMGGLGAGERWADLAMGPRPHSVWGSSRWLRASQPQALLVIARGLQTSGREHAGCRFRFGRQDEGSEATGFLPAAGEKTSGPLGNLAEELNGYSRKKGGFSFRFGRR
What is the function of this protein?
Stimulates feeding behavior, metabolic rate and locomotor activity and increases blood pressure.  May have orexigenic activity.  May promote aldosterone secretion by the adrenal gland (By similarity).
What are the official names of this protein?
Orexigenic neuropeptide QRFP, P518.
What is the protein family that this protein belongs to?
Belongs to the RFamide neuropeptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: TNMD_HUMAN
Sequence: MAKNPPENCEDCHILNAEAFKSKKICKSLKICGLVFGILALTLIVLFWGSKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLISVSELQDFEEEGEDLHFPANEKKGIEQNEQWVVPQVKVEKTRHARQASEEELPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV
What is the function of this protein?
May be an angiogenesis inhibitor.
What are the official names of this protein?
Tenomodulin, TeM, hTeM, Chondromodulin-1-like protein, ChM1L, hChM1L, Chondromodulin-I-like protein, Myodulin, Tendin.
What is the protein family that this protein belongs to?
Belongs to the chondromodulin-1 family.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Single-pass type II membrane protein. Nucleus envelope. SUBCELLULAR LOCATION: [Isoform 2]: Membrane; Single-pass type II membrane protein. Nucleus envelope. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm.
Protein: Y497_RICPR
Sequence: MGRKNDIIQKIDSFIGQKIYSLRLAKGLSRQQLAEVIDVTHQQLQKYEKAINRISVGRLVLIAEALDRNIDYFFEGLEEANKPQPVHTQHQRMCIEVSRNFMKINSTEEQQAINNLVKCLAGKEKLKTNV
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator RP497.