PharMolix/UniProtQA huggingface dataset:
Protein: VAT1L_MOUSE
Sequence: MAKEGVEKAEETEQMIEKETSKEPAEGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLSRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYTMLFEIANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRSGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ
What are the official names of this protein?
Synaptic vesicle membrane protein VAT-1 homolog-like.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: ABCG4_MOUSE
Sequence: MAEKALEAVGCGLGPGAVAMAVTLEDGAEPPVLTTHLKKVENHITEAQRFSHLPKRSAVDIEFVELSYSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAHGGRTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCTMAEKKSSPGKNELPAHCPTCPPELDPIESHTFATSTLTQFCILFRRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYLHIGDDASKVFNNTGFLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYTLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALAIATALVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGLILTIYGMERGHLTCLDEQCPFRDPQIILRELDVEEAKLYMDFLVLGIFFLALRLLAYLVLRYRVKSER
What is the function of this protein?
ATP-dependent transporter of the ATP-binding cassette (ABC) family that may be involved in the cellular efflux of sterols, in particular cholesterol and desmosterol (a cholesterol precursor), to high-density lipoprotein (HDL) (PubMed:15210959, PubMed:18039927, PubMed:17916878).  May play an important role in the removal of amyloid-beta peptides from brain, in a process that can be antagonized by desmosterol.  However it is unclear whether ABCG4 can directly transport amyloid-beta peptides or whether peptide export may be facilitated due to changes in the membrane lipid environment (PubMed:29042617).  Induces apoptosis in various cells (By similarity).
What are the official names of this protein?
ATP-binding cassette subfamily G member 4, ATP-binding cassette transporter White2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endosome membrane; Multi- pass membrane protein.
Protein: RL34_CAMFF
Sequence: MKRTYQPHKTPKKRTHGFRGRMKTKNGRKVINARRAKGRKRLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LACA_STRZJ
Sequence: MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTLAVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMITMGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: YPDA_ECOLI
Sequence: MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWAPTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIHADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL
What is the function of this protein?
Member of the two-component regulatory system YpdA/YpdB, which is part of a nutrient-sensing regulatory network composed of YpdA/YpdB, the high-affinity pyruvate signaling system BtsS/BtsR and their respective target proteins, YhjX and BtsT.  YpdA activates YpdB by phosphorylation in response to high concentrations of extracellular pyruvate.  Activation of the YpdA/YpdB signaling cascade also promotes BtsS/BtsR-mediated btsT expression.
What are the official names of this protein?
Sensor histidine kinase YpdA.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VLP10_BORHE
Sequence: MRKRISAIIMTLFMVLASCSNQLEAEKLAAESKNTFFDSLVKIGQGFQDIFGILEMQLGDALGFNAVKSGDKKSKVGEHFKKIGDGLTTTKDKLKELSNKISEAKNANSSTIEAVKSAINSASDVFEQLITALTKLADTAKEAGDTNIGDNADAVPGAAEKTGVEAIIAGVKDIIGAAEKSGVKIEYGNAGDPIATAANTTDALAVLGGNTAKATQGAGDKLAFEVSKADPWAIIDKIKNAKAADGIQLDAGEKDAGTLAASNNNASANAGAESNAASSSSWLFLMQLSKGGKFSAAVADAGAVKAAAVSAVNKVLGVLDFIIRKTVSSNLDKIREAVKGIKYSEITETDATESGDAQPITNKSSN
What is the function of this protein?
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time.  Switching between these genes is a mechanism of host immune response evasion.
What are the official names of this protein?
Variable large protein 10.
What is the protein family that this protein belongs to?
Belongs to the variable large protein (Vlp) family. Beta subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ISDB_STAAR
Sequence: MNKQQKEFKSFYSIRKSSLGVASVAISTLLLLMSNGEAKAAEETGVTNTEAQPKTEAVASPTTTTTEKAPEAKPVAKPVANAVSVSNKEVVAPTTETKEAKEVKAVKEVKAPKEAKEEKPAAKADNNTYPILNQELREAIKNPAIKDKDHSAPNSRPIDFEMKKKDGTQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGDKKLPIKLVSYDTVKDYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKTEEDYKAEKLLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEETKKALDEQVKSAITEFQNVQPTNEKMTDLQDTKYVVYESVENNESMMDAFVKHPIKTGMLNGKKYMVMETTNDDYWKDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDKEAFTKANADKTNKKEQQDNSAKKETTPAMPSKPTTPPVEKESQKQDSQKDDNKQSPSVEKENDASSESGKDKMPVTKPAKAEVESSSTTPTKVVSTTQNVAKPTTASSETTKDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSQNNKNTQENKAKSLPQTGEESNKDMTLPLMALIALSSIVAFVLPRKRKN
What is the function of this protein?
Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source.  Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization.  Promotes also resistance to hydrogen peroxide and killing by neutrophils.
What are the official names of this protein?
Iron-regulated surface determinant protein B, Fur-regulated protein B, Staphylococcal iron-regulated protein H, Staphylococcus aureus surface protein J.
What is the protein family that this protein belongs to?
Belongs to the IsdB family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A.
Protein: ACBD5_RAT
Sequence: MLFLSFYAGSWESWICCCCVIPVDRPWDRGRRWQLEMADTRSVYETRFEAAVKVIQSLPKNGSFQPTNEMMLRFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLHVIGPFYEIVEDKKNSKSSDLTSDLGNVLTSSNAKAVNGKAESSDSGAESEEEEAQEELKGAEQSGSDDKKMMTKSTDKNLEIIVTNGYKDSFAQDSDIHTDSSRSARRSEDKKPTDQSSQQTGNTVLCVHQDTNEDPGEDASGVHHLTSDSDSEVYCDSMEQFGQEEYYLGGDPAQHLEGSGFCEDAQLSPGNGSIGKMQMRAVKGKGEVKHGGEDGRSSSGTPHREKRGGESEDISGVRRGRGHRMPHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLIRLQEDMQNVLQRLHKLETLTASQAKLSWQTSNQPSSQRPSWWPFEMSPGALAFAIIWPFIAQWLVHLYYQRRRRKLN
What is the function of this protein?
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy.  Binds medium- and long-chain acyl-CoA esters (By similarity).
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG37 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: IP5P5_ARATH
Sequence: MNNRGNNDDLDHHYGVFNDFERRMTSRKKSVLDNTSPMIWKTVSERKSSPGIEGLNLSSFDRPMAPTTEIRELRVFLATWNVGGRTPNNDLNLEDFLLVEGTADLYICGFQEIVPLSAGNVLVVEDNEPAAKWLALISQALNKPKQESVYSNAAYSASRTTTCSSSSCGSEESRAPSSLSFFQRPNLKVLSRNYRVDSSLLKTCNCPVIDTSVGWEARRSKRFSDPSTDSSNNVEPENFRVHENFLFDDVPATTKMPGQMSYRLIASKQMVGLFLSVWARRELIPHISHLRLDSVGRGIMGRLGNKGCIAISMSLHQTSFCFVCSHLASGEKEGDELRRNADVAEILKHTQFPKLTKNPNCHAPERIIDHDRVLWLGDLNYRVALTYEETRVLLEDNDWDTLLERDQLNMERGAGRVFSGFQEGQIFFAPTYKYSQNSDAYAGEMTKSKKKRRTPAWCDRILWKGEGIEQLSYIRGESRFSDHRPVCAIFAVEVDVKSLNKGRFRKGYSCAAVRLVEDVAIPQRHSFYD
What is the function of this protein?
May be involved in the regulation of root hairs development.  Required for restricting both the size of the root-hair initiation site and the width of the root hairs during the transition to tip growth, but is not required for normal subsequent tip growth.
What are the official names of this protein?
Type I inositol polyphosphate 5-phosphatase 5, At5PTase5, Protein BRISTLED 1, Protein DEFORMED ROOT HAIRS 4.
What is the protein family that this protein belongs to?
Belongs to the inositol polyphosphate 5-phosphatase family.
Protein: AURT_GIBZE
Sequence: MTDNTDMEKLDRATTPTPIPNEAPPTSEPSESKPEEAEDESKYPHGLKLAAIILSNMVAMFLVALDRTIIATAIPRITDDFNALGDISWYASAYLITSSATQLLWGRIFTFYPTKTVYLVAIFFFELGSLLCGVAPNSVAFIIGRAIAGAGSAGIYSGSTILITTVTPLSKRAGYVGMMGAVFGIASVIAPLIGGAFTDHVTWRWCFYINLPVGGAAVACLILLFPKFPVNEPVSVKQQIKQLDPWGNLVFLPGVICLILALQWGGEKYAWDSGRIVALLVLACVLLLVFIGIQIWQQENATVPPRLFKIRNVWLGTIFAFCLGSVLIVFLIALPIWFQGIRGTDAITSGIDTLPLVLSLVFGAIVSGGVINGVGWFNPVFFSSVIFMSVGGGLITTFVVDTPTRTWIGYQIILGLGIGQGMQLASLGTQVAVKQSDVPTGVSLMFFAQSLGGSVLVCVAQAVFNNELRSRLTSFDGIDVARIIGTGATQLRHVIPADRLAEVLVEYNAALRSYFYVGLAAACFAVLPSLGIEWKNVKGQEFVH
What is the function of this protein?
Rubrofusarin-specific efflux pump; part of the gene cluster that mediates the biosynthesis of aurofusarin, a red mycelium pigment which is acting as a mycotoxin (PubMed:15811992, PubMed:15809006, PubMed:16879655).  The first step is performed by the polyketide synthase which condenses one acetyl-CoA and 6 malonyl-CoA units to form the first intermediate, the cyclic heptaketide and yellow pigment YWA1 (PubMed:21296881, PubMed:23557488).  The C2 hydroxyl group in the pyrone ring of YWA1 is probably formed during ring closure by an aldol-type cyclization reaction (PubMed:21296881).  The dehydratase aurZ then acts as the first tailoring enzyme in the aurofusarin biosynthetic pathway by converting YWA1 to nor-rubrofusarin (PubMed:21296881, PubMed:23557488).  Nor-rubrofusarin is then methylated to rubrofusarin by the O-methyltransferase aurJ (PubMed:21296881, PubMed:23557488).  Rubrofusarin is then transported across the plasma membrane by the rubrofusarin-specific pump aurT for further enzymatic processing by the extracellular complex composed of GIP1, aurF, aurO and aurS to yield aurofusarin (PubMed:21296881).
What are the official names of this protein?
Rubrofusarin-specific efflux pump aurT, Aurofusarin biosynthesis cluster protein T, Gibberella pigment protein 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OMH5_SCHPO
Sequence: MKRYDTLHVWKLIKLLICKFLLFHDFGTALFTSLVKASMLGFHNWRRTYWLYLKKLRPINDTYDAPFAIGCKNVAYEASQYPRMNATFMVLARNSDLDGVLSSMNSIERRFNRHFKYPYVFLNDEPFTTEFKKAVKDATDSSIQFGVLDDELWNFPKDVDKDMIDESIAEQVGVVYANFPSYHKMCRFFSRNFYKHPLMQQYEWYWRLEPEVTFSCDISYDPFYYMDKHNKVYGYVIAIKELAKTVPNLFRYTVAHQKISNLPTTDLWSFFLDKRYETRIKKLKEEQKDQGYYVLPEPPLNRIDGQIYNLCHFWSNFEIARLDFYNSKEYNEYVDALENAGGFWTERWGDAPVHSLAVGLLLNRSQVHYFRDLGYQHSTIQHCGQEYGCNCDCPFNIPDYETKPGSCINEWASVMGGFLDE
What is the function of this protein?
Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins.
What are the official names of this protein?
O-glycoside alpha-1,2-mannosyltransferase homolog 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_BART1
Sequence: MANTPSARKAVRKVAARTQVNKARRSRVRTFMRKFDDALAGGDKASAEIAFKNFEPEIMRAVSKGVFHKNTAARKVSRLAKRLKALSV
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SYR_EDWI9
Sequence: MNIQEIISDKVTQALVAAGAPAGSEALVRPSAKVQFGDYQANGIMSAAKKMGLPPRQLAEQVVANLALDGIASKVEIAGPGFINIFLDAAWLAAQADAALADPRLGVARVEPQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKVQGSSETGDMALADLEAFYREAKKHYDEDAAFAERARGYVVKLQGGDEYCREMWRKLVDITMRQNQRNYDRLNVTLTDDDVMGESLYNPMLPGIVADLKAKGLATESEGATVVFLNEFRNKEGEPMGVIVQKKDGGYLYTTTDIACAKYRYETLGANRILYYIDSRQHQHLMQAWTIVRKAGYVPDSVSLEHHMFGMMLGKDGKPFKTRAGGTIKLADLLDEAIERAAKLIAAKNPELSGDELKALVEVVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFKRAGIDENTLQGAITLTEEREKALATRLMQFEETILSVAREGTPHVMCAYLYEVAGLFSSFYEACPILNAEEESVRASRLKLAALTARTLKTGLDTLGIKTVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_SALPC
Sequence: MSHLAELVANAAAAINQASDVAALDNVRVEYLGKKGHLTLQMTTLRDLPPEERPAAGAVINAAKEQVQQALNARKAELESAALNARLAAETIDISLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD2_CULQU
Sequence: MAPTAAVPLAKPSQESPVGINAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEIAAGSKIGAQLKKVMDEGKLVSDDLVVDMIDSNLDKPECRNGFLLDGFPRTVVQAEKLDQLLDKRNTGLDAVIEFGIDDSLLVRRITGRLIHQASGRSYHEEFHPPKVAMTDDVTGEPLMRRSDDNAHALVKRLESYHKQTKPLADYYALRGLHFRVDAARSASQVFEHIDSIFMKQRSARLGL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: HSPQ_KLEP7
Sequence: MIASKFGIGQQVRHTLLGYLGVIVDVDPEYSLAEPEEDEIAANDELRAAPWYHVVMEDDDGQPIHTYLAEAQLSSETRDEHPEQPSLDELAKTIRQQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTB_YERPY
Sequence: MAGYEVNFDGLVGLTHHYAGLSFGNEASTTHQNRTSNPRLAAKQGLLKMKALADLGYKQGVLPPQERPAIGVLRKLGFSGSDEQVLSDVARNAPRLLSAVSSASSMWTANAATVSPSADSADGRVHFTVANLHNKFHRAIEAETTAVLLPAVFNNHRHFVHHDALPSVTLLGDEGAANHNRLGGEYDSPAIQMFVYGRQGMESGAVPGRYPARQTREASQAVARLHQLDPKRTVFVQQNPAVIDQGVFHNDVIAVSNRNVLFHHELAFLSSTQVMDDIRCKMAGLEQQLVNIEVPEAEVSVADAVSTYLFNSQLLHKANGKMLLVIPQESQDNPSVWRYLSELVSGDGPIDELRVFDLRESMRNGGGPACLRLRVVLNDAELQAVNSRVMLTPALFVTLNNWVDQHYRDHLQFKDLADPHLLQEGRQALDELTRILNLGPVYPFQRN
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: VM3H1_PROFL
Sequence: MIQVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTALPKGAVQQKYEDAMQYEFTVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTNPPVEDHCYYHGRIQNDADLTASISACDGLKGHFKLQGETYIIEPLKLPDSEAHAVFKYENVEKEDEAPKMCGVTQSNWESDESIKEDSQSNLTPAQQKYLNAKKYVKFFLVADHIMYLKYGRNLTTLRTRMFDTVNIVNQILQRINIHVALIGIEIWSKEDKIIVQSVPDVTLKLFATWRESVLLKRKNHDNAHLLTGINFNGPTAGLAYLGGICKPMYSAGIVQDHNKIHHLVAIAMAHEMGHNLGMDHDKDTCTCRAKACVMAGTLSCDASYLFSDCSRQEHRAFLIKNMPQCILKKPLKTDVVSPPVCGNYFVEVGEDCDCGSPATCRDPCCDAATCKLRQGAQCAEGLCCDQCRFKAAGTECRAATDECDMADLCTGRSAECTDRFQRNGQPCQNNNGYCYNRTCPTMNNQCIALFGPNAAVSQDACFQFNRQGNYYGYCRKEQNTKIACEPQNVKCGRLYCIDSSPAKKNPCNIIYSPNDEDKGMVLPGTKCADGMACNSNGQCVDVNRTY
What is the function of this protein?
Snake venom zinc metalloproteinase-disintegrin-like that potently activates prothrombin (F2).  Does not elicit any hemorrhagic response.  Barely inhibits collagen-induced platelet aggregation.  Hydrolyzes the alpha-chain of fibrin and fibrinogen (FGA), without affecting the Bbeta- and gamma-chains (By similarity).  Induces apoptosis in cultured vascular endothelial cells.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like HV1, Snake venom metalloproteinase, SVMP, Vascular apoptosis-inducing protein, VAP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIc sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PESC_DEBHA
Sequence: MRIKKKGTSGNAKNFITRTQAVKKLQVSLADFRRLCIFKGIYPREPRNKKKANKGSTAPVTFYYTKDIQYLLHEPVLGKFREHKTFAKKLQRALGRGEVSDAQKLEGNRPKYTLEHIIKERYPTFLDALRDIDDPLNMLFLFANMPATDKVSHRITKEAEKLTNQWLAYVAKERLIKKVFVSIKGVYYQANVKGQEVRWLVPFKFPTNIPTDVDFRIMLTFLEFYSTLLHFVLFRLYNDANLIYPPTIDTEKLKGIGGLSSYVLQSKDQGVKALLPNAKKAADSKDESKKVKETKLSKEEISKAVAADKSLNENAEDNVSENVEDVELDEFSSTNKTAGDLLSQPSKFASPTSTLLSKFIFYVGREVPLDILEFCILSCGGSIISEIALDELQLNQPEEYKKLDLSNITHQIVDRPTVASKVAGRTYVQPQWVFDCLNKSELLPVSQYAPGETLPPHLSPWGDAGGYNPDAEVKPTEQGEEEEEEEEEIEGDEIEEDVEEEDEEEDEDLQAQKELELEAAGVKSADAQKKDKKSSKGKKRSAEDEEKDLKKIMMSNKQRKLYKKMQYGIDKKEARQDDLTKKRRKLEKTKAELGKLNKKN
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Pescadillo homolog, Nucleolar protein 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: ATPD1_SYNC1
Sequence: MKSTAISRRYAKALVNLAAPDGQLESTYAQLEQLQQAFACEPRLYKLLASPTLAADKIAGLLEGISNYLQLSTTLRNLLGLLQQRQRLEYFDALVADYRELADVQLGLVRARVCSAAPLDAAVQQAISAQLQKRYGKQAVLELAVEPELLGGVRIEVAGQVLDGTIRSGLRRMAGYLNS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta 1, ATP synthase F(1) sector subunit delta 1, F-type ATPase subunit delta 1, F-ATPase subunit delta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLB2_ASCSU
Sequence: MATACVKSLESVQCGTCEKTIANGTEFYALLFDKHPDLRHYFKGNENLTGADVKKSDHFKKQGQRLLLACHVLAHLENDPASFKAYAREIVDPHLRMSVHLEPKLWSEFWPIWLDYLSTKESVDDATKNAWLALGKKFSDECLDHLKNLGQPH
What is the function of this protein?
High oxygen affinity.  Probably supplies oxygen needed for muscle activity.
What are the official names of this protein?
Myoglobin, Globin, body wall isoform.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRIP1_MOUSE
Sequence: MTHGEELGSDVHQDSIVLTYLEGLLMHQAAGGSGTAINKKSAGHKEEDQNFNLSGSAFPSCQSNGPTVSTQTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIVNLNVKKEALLAGMVDSVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHESLKVEKDLRCYGVASSHLKTLLKKSKTKDQKSGPTLPDVTPNLIRDSFVESSHPAVGQSGTKVMSEPLSCAARLQAVASMVEKRASPAASPKPSVACSQLALLLSSEAHLQQYSREHALKTQNAHQVASERLAAMARLQENGQKDVGSSQLSKGVSGHLNGQARALPASKLVANKNNAATFQSPMGVVPSSPKNTSYKNSLERNNLKQAANNSLLLHLLKSQTIPTPMNGHSQNERASSFESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRIEKPEAERPVSLENLTQSLLNTWDPKIPGVDIKEDQDTSTNSKLNSHQKVTLLQLLLGHKSEETVERNASPQDIHSDGTKFSPQNYTRTSVIESPSTNRTTPVSTPPLYTASQAESPINLSQHSLVIKWNSPPYACSTPASKLTNTAPSHLMDLTKGKESQAEKPAPSEGAQNSATFSASKLLQNLAQCGLQSSGPGEEQRPCKQLLSGNPDKPLGLIDRLNSPLLSNKTNAAEESKAFSSQPAGPEPGLPGCEIENLLERRTVLQLLLGNSSKGKNEKKEKTPARDEAPQEHSERAANEQILMVKIKSEPCDDFQTHNTNLPLNHDAKSAPFLGVTPAIHRSTAALPVSEDFKSEPASPQDFSFSKNGLLSRLLRQNQESYPADEQDKSHRNSELPTLESKNICMVPKKRKLYTEPLENPFKKMKNTAVDTANHHSGPEVLYGSLLHQEELKFSRNELDYKYPAGHSSASDGDHRSWARESKSFNVLKQLLLSENCVRDLSPHRSDSVPDTKKKGHKNNAPGSKPEFGISSLNGLMYSSPQPGSCVTDHRTFSYPGMVKTPLSPPFPEHLGCVGSRPEPGLLNGCSVPGEKGPIKWVIADMDKNEYEKDSPRLTKTNPILYYMLQKGGGNSVTTQETQDKDIWREPASAESLSQVTVKEELLPAAETKASFFNLRSPYNSHMGNNASRPHSTNGEVYGLLGNALTIKKESE
What is the function of this protein?
Modulates transcriptional repression by nuclear hormone receptors such as NR2C1, thyroid hormone receptor and retinoic acid receptor/RARA.  Essential for cumulus expansion and follicle rupture during ovulation.  Also controls the balance between fat accumulation and energy expenditure.  Positive regulator of the circadian clock gene expression: stimulates transcription of BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC.  Involved in the regulation of ovarian function (PubMed:11100122).  Plays a role in renal development (PubMed:28381549).
What are the official names of this protein?
Nuclear receptor-interacting protein 1, Nuclear factor RIP140, Receptor-interacting protein 140.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL6_TREPA
Sequence: MSRIGKVPVSVPGGVHVRVSSGVVEVEGPKGVLSCAFLPVVTVRVEQEYVIVARCDDSKRARACHGLYRKLLSNMVVGVSEGFSKTLVITGIGYRAEVQGRVLVMALGYSNDFTVLIPSGIEVRVESSTRVIVSGVSKERVGEFAAQLRRLRLPEAYKGKGIRYDYETIVRKVGKSGVK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CHED_BORBZ
Sequence: MLNHFNFKLKRDVTIIVPGEAFVSNKRVISTILGSCVAVVLCDESNNLIGMNHYVLVKSDLDISPDQRGRYGIYAIPMLINAMLENGASKSNLKAKLFGGTNFMAKGSVKVGLENSEFAVNTLNKYRIPILAKDFDQSKSRKIFAFPENFKVIVEYPDGTKVF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.