PharMolix/UniProtQA huggingface dataset:
Protein: RN185_HUMAN
Sequence: MASKGPSASASPENSSAGGPSGSSNGAGESGGQDSTFECNICLDTAKDAVISLCGHLFCWPCLHQWLETRPNRQVCPVCKAGISRDKVIPLYGRGSTGQQDPREKTPPRPQGQRPEPENRGGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPPAVPGTPQYVDEQFLSRLFLFVALVIMFWLLIA
What is the function of this protein?
E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1 (PubMed:21931693).  Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation (PubMed:27485036).  Protects cells from ER stress-induced apoptosis (PubMed:27485036).  Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway (PubMed:24019521).  Also acts as a regulator of the innate antiviral response by catalyzing 'Lys-27'-linked polyubiquitination of CGAS at 'Lys-173' and 'Lys-384', thereby promoting CGAS cyclic GMP-AMP synthase activity (PubMed:28273161).  Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2 (PubMed:24019521).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF185, RING finger protein 185.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HSCB_VIBCH
Sequence: MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQTLKDPLRRAEYLLSLQGIEMNAEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDTKVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKNEVERVEDQLLG
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: SLYX_ECOL6
Sequence: MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: ATPB_TROW8
Sequence: MTGDAVGRIVRVTGSVVDVEFSRNNLPGVFNALKTRVNRSGKEIEITLEVAQHLGDDLVRTVAMQSTDGLIRGQEVLDTGGHITVPVGDATKGRVFNVVGEVLNSNGEDIKFDEYWSIHRKPPEFSLLESKTQLFETGIKVIDLLTPYVQGGKIGLFGGAGVGKTVLIQEMIQRVAQDHGGVSVFAGVGERTREGNDLIREMQDAGVFDKTALVFGQMDEPPGTRLRVALSALTMAEYFRDVQKQDVLLFIDNIFRFTQAGSEVSTLLGRIPSAVGYQPNLADEMGVLQERITSTRGHSITSLQAIYVPADDYTDPAPATTFAHLDATTELSREIASKGLYPAVDPLASTSRILDPKYIGKDHYRVAVTVKQILQRDKELREIIAILGIDELSEEDRVTVARARRIEQFLSQNTYMAKKFTGVDGSTVPLQETIDGFDAICRGDCDHIPEQAFFNVGGLEDVERKWSKLQKELG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YL285_MIMIV
Sequence: MKLLSVLALLMFIGVVLADNDCYNPKCGRGHFNLKGKKPLCVPPAPILTEKYFTNITNHIAVVVDSTVTKPGQQSQLDVQKEYFNRLTLGPWKAPSVFRNYTAYYCGDAIPFNVNIHLTASRDYDNGTAFHEIFELVDKSSNFFRDWYDEMGPSIVYHGLMLKTDDNGVPVMNACQLRQYMEQQNFQLVFHLPSCPKDAYFFRAGYAHVEVVIPC
What are the official names of this protein?
Uncharacterized protein L285.
Protein: FUT3_PANTR
Sequence: MDPLGAAKPQWPWRRCLAALLFQLLVAVCFFSYLRVSRDDATGSPRPGLMAVEPVTGAPSGSSRQDTTPTRPTLLILLWTWPFHIPVALSRCSEMVPGAADCHITADRKVYPQADAVIVHHWDIMYNPKSRLPPSPRPQGQRWIWFNLEPPPNCQHLEALDRYFNLTMSYRSDSDIFTPYGWLEPWSGQPAHPPLNLSAKTELVAWAVSNWKLDSARVRYYQSLQAHLKVDVYGRSHKPLPKGTMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLRPRSFSWALDFCKACWKLQQESRYQTMRSIAAWFT
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to both the subterminal N-acetyl glucosamine (GlcNAc) of type 1 chain (beta-D-Gal-(1->3)-beta-D-GlcNAc) glycolipids and oligosaccharides via an alpha(1,4) linkage, and the subterminal glucose (Glc) or GlcNAc of type 2 chain (beta-D-Gal-(1->4)-beta-D-GlcNAc) oligosaccharides via an alpha(1,3) linkage, independently of the presence of terminal alpha-L-fucosyl-(1,2) moieties on the terminal galactose of these acceptors and participates in the blood groups Lewis determination and expression of Lewis a (Le(a)), lewis b (Le(b)), Lewis x/SSEA-1 (Le(x)) and lewis y (Le(y)) antigens.  Also catalyzes the transfer of L-fucose to subterminal GlcNAc of sialyl- and disialyl-lactotetraosylceramide to produce sialyl Lewis a (sLe(a)) and disialyl Lewis a via an alpha(1,4) linkage and therefore may regulate cell surface sialyl Lewis a expression and consequently regulates adhesive properties to E-selectin, cell proliferation and migration.  Catalyzes the transfer of an L-fucose to 3'-sialyl-N-acetyllactosamine by an alpha(1,3) linkage, which allows the formation of sialyl-Lewis x structure and therefore may regulate the sialyl-Lewis x surface antigen expression and consequently adhesive properties to E-selectin.  Prefers type 1 chain over type 2 acceptors.  Type 1 tetrasaccharide is a better acceptor than type 1 disaccharide suggesting that a beta anomeric configuration of GlcNAc in the substrate is preferred.  Lewis-positive (Le(+)) individuals have an active enzyme while Lewis-negative (Le(-)) individuals have an inactive enzyme.
What are the official names of this protein?
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase, Alpha-3-fucosyltransferase FUT3, Alpha-3/4-fucosyltransferase, Blood group Lewis alpha-4-fucosyltransferase, Lewis FT, Fucosyltransferase 3, Fucosyltransferase III, FucT-III.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: DAAF1_AEDAE
Sequence: MVRECVEESFGPKKMTKKSIVDSCKKNKLYITPHLNDILYLNYSGYNAIESLEEYVGLKCLWLECNAISEIKGLEYQTELKCLYLQNNLITKIENLDSCKQLDTLNLSHNHITRIENCGHDILPVLNTLNLSHNYLKTADNLDHLRHCNFVSVLDLSHNRIEDIAIVKILGGMKELRVLTMTGNPVVNEIPSYRKTLILECKNLTYLDTRPVFDRDRACAEAWKRGGYEEERKELLRWKKEEQRKIRRSINATLRMRHRGDGEPELLKTSSDEEDEDKASKCGKDMSSMLEINQKTNEQAWAEVEKMFCTTPSATGSSGIFQRFATNRGGGADGDGEVIETSEEDIEATIEDIKAVSPKKLIEEISSDSDGAKENYDCKPDEVIAKPCSEKLIEEIVIETAECDSGPSSPEYHEALDKPIENIVNLTNESPLTSPSFDTEPRTLIEEIEPTDVEEEQQIEEQPAPKPLSKNMEKVMSTEKEDDTLNVLIENNEEISITMESKDGELISKVESRPPSTECKKYKIVSTNDVDNSESEPTDITNEDQEYRSSSVSVTSSTDSSDSEDLFDKIVPNKHPKLATNYRQDSTTSTDSENEVSPSKPPIKLEKEKSIAECIDEYKKFFKAAKILESDPEDESSTKMARPHTAKAKRTEPIIYEGVLRNMERNSNESKIAEARTEAKESKEKVIDRLIEQQNLVDMNLEEQNISIGGQEHDFNEYRLEAFRKDQEKLQCLIDRVTAQKDLYNAHIDQIHNQLANIMEDYDQIGLKLKKVDDFLENIKEEPKAPETPSIESEEEIPEELEVHSSEHEQEIVENDNLAQQIIEKIISQSVKTSSEDLKSNFDDSSESSDSAEEDFMDSIRPDHNLLEILTSPKPIPILDPELIPNVDNEFQRDPVYRKFIEIQEEIDKLTEDELYDIVTEATGEFSEEAHVEHCLNTQVDQYWKQYDDIEEFRKNINLDSHPIIQKFRQFIRCHCENKYPGEVDSTIDNLDKACRKLERRLSNQLFDEYLELSRKMSVATIGGESSANEIELIEVDEEENDVEDVVKKITAWVEEQVQNEIAELNEERAAHAGEVMQDTEDVESKPVEIDGTKEETVDSELADNCD
What is the function of this protein?
Cilium-specific protein required for cilia structures.
What are the official names of this protein?
Dynein axonemal assembly factor 1 homolog, Leucine-rich repeat-containing protein 50.
What is the protein family that this protein belongs to?
Belongs to the DNAAF1 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: WHIA_MYCLB
Sequence: MAMTIEVKDELSRLAVKSISARRAEVTSLLRFAGGLHIVGGRVVIEAEVDLENIARRLRKDIFDLYGYNAVVHVLSASGIRKSVRYVLRVANDGEALARQTGLLDMRGRPVRGLPAQVVGGSLIDAEAVWRGAFLAHGSLTEPGRSSALEVSCPGLEAALALVGAARKLGVNAKAREVRGADRVVVRDGEAIGVLLTRMGAQDTRLVWEERRMRREVRATANRLANFDDANLRRSARAAIAAAARAERALEILGDTVPDHLASAGKLRVEYRQASLEELGRLADPPMTKDAVAGRIRRLLSMADRKAKVEGIPDTESAVTPDLLEDA
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RL25_NITWN
Sequence: MATVMELKATARPKSGKGAARAERRAGRVPAVIYGNKQPPQPISVEEPELRQRILAGRFLTTIFDINLDGKKHRVIPRDFHLDPVKDFPIHVDFMRLGEGATIRVSVPLRLLKADVAPGVKRGGTVNLVTHAIDVECAAESIPQFIEADVGALEISHSLHLSDLQLPPGVKPLAREDVTLVTIVPPSGYAEELKAAAAAGAAAPAAGAAPAAAAAGAKAPAGGGDKKK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: Z_SHEEP
Sequence: MSSSLEITSFYSFIWTPHIGPLLFGIGLWFSMFKEPSHFCPCQHPHFVEVVIPCDSLSRSLRLRVIVLFLAIFFPLLNI
What are the official names of this protein?
Putative uncharacterized protein Z.
Protein: CYB_ICHAL
Sequence: MTNIRKSHPLIKIVNESFIDLPAPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGVYYGSYTFMETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGISSDSDKIPFHPYYTIKDILGLLVMLMLLMTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSIMVLAIVPLLHTSNQRGMMFRPLGQCLFWLLVADLLTLTWIGGQPVGHPFITIGQLASILYFSIILILMPIFGTIENQLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BUDR_RAOTE
Sequence: MELRYLRYFVAVAEARNFTRAAHDLGISQPPLSQQIQRLEREIGTPLLRRLTRGVELTEAGESFYVDACQILALSDAALEKTKGIARGMNGSLVPGITSSAAFHSQIFSLLYQFQQRYPAVALRQVEGNMATLMHALGEAELDIAFVRLPCESSKAFNLRIIAEEPMVIALHRSHPLSGESALSLAQLSDAVPVIFPPEVAPGLYEQVYDGCRRAGVDMSRARQSSQISSSISMVDAGFGFALVPQSMTCICLPNVTWHPLQDASLKTEIAIAWRRFERSRTVKRFLEMF
What is the function of this protein?
Regulator of the budABC operon for 2,3-butanediol synthesis.
What are the official names of this protein?
HTH-type transcriptional regulator BudR, Bud operon transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GLYA_STAAW
Sequence: MSYITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFVDVTESIAIDRAKALFGAEHVNVQPHSGSQANMAVYLVALEMGDTVLGMNLSHGGHLTHGAPVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMILCKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKIISLALKNSKDEEKLQQAKERVAKLTAEYPLYQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_MARMS
Sequence: MDFPSRFDVIVVGGGHAGTEAALAAARMGVKTLLLSHNIETLGQMSCNPAIGGIGKSHLVKEIDALDGAMALATDQAGIQFRTLNSRKGPAVRATRAQADRILYKAAIRHKLENQENLWLFQQSAEDLIVENGAARGVITQTGIRFNSKTVVLTAGTFLGGVIHIGLENHSGGRAGDPPSIGLAQKLRALPFRVDRLKTGTPPRIDARSVDFSQMQAQPGDDIDPVMSYMGNRAMHPRQIECFITHTNERTHDIIRAGMDRSPMYTGVIEGVGPRYCPSIEDKIVRFADKNSHQIFIEPEGLTTHELYPNGISTSLPFDVQIELVRSMKGMENAHIIRPGYAIEYDYFNPQDLKYSLETKHMPGLFFAGQINGTTGYEEAGAQGLLAGLNAALLAQEKDAWTPRRDEAYLGVLVDDLISMGTKEPYRMFTSRAEYRLILREDNADMRLTEKGRELGLVSDERWAAFCKKREAIELETQRLRSSWIVPNTPEADSINPKLETPITHEYSLLDLLKRPNIVYSDIANLKNGLDEPVDEQVSEQVQIAVKYAGYISRQAEDIERLRRQENTELPDDLDYSKMEGLSNEIKQKLTQLRPATLAAASRIQGVTPAAVSLLLIHLKKRAIARKSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EAF3_CANAL
Sequence: MVEYKPNQTVYAYHGPLIYEAKILKLKNGKDSFIINQDFQHEPLEEKPNSSGNHHHHHHSQHIAKFDPKKWQDQTCYYLHYQGWNSKWDEWVGIDRIMEYNEENKFKKLELDQLTKKKKAINNNEIIVNATTKNHTNNKNKKESNKRKSSSATTTSGVTAGTNNNKKQKSASTSTTNNTSGNSGTTSNKSKQILSRLNLNFPPELKHILVNDWEYITKDRKLVSLPSQYPINQILQDYKTYRTKQLTSNSDQLSILIEILTGLEIYFNKSLSLILLYKYEHLQYLNFLKQNIINPQQDILQSNIYGVEHLLRLIISFPGLLSTTTMDGISLSVLISELESLCRFIGDRLQLYQNNYEFTSPQYDSLARS
What is the function of this protein?
Involved in deacetylation of histones, chromatin assembly and chromosome segregation.  May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF3.
What is the protein family that this protein belongs to?
Belongs to the MRG family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RASK_MONDO
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGGDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKCIIM
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity).  Plays an important role in the regulation of cell proliferation (PubMed:8312604).  Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (By similarity).
What are the official names of this protein?
GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol.
Protein: CH10_LEUCK
Sequence: MLKPLGDRVIIEVTEAAEQTVGGIVLANNAKDKPVTGKVVAVGSGYVLNDGSKQDLTVKSGDQVLFDKYAGQEVSFEGADYLALHEKDIVAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPE_ECO57
Sequence: MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTPPAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQRLHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLMKALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLHDETRAQMDKLWLALAGGKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIALVDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG
What is the function of this protein?
Reduces the stability of FtsZ polymers in the presence of ATP.
What are the official names of this protein?
Cell division protein ZapE, Z ring-associated protein ZapE.
What is the protein family that this protein belongs to?
Belongs to the AFG1 ATPase family. ZapE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_CORGB
Sequence: MTVAPRIGTATRTTSESDITVEINLDGTGKVDIDTGLPFFDHMLTAFGVHGSFDLKVHAKGDIEIDAHHTVEDTAIVLGQALLDAIGDKKGIRRFASCQLPMDEALVESVVDISGRPYFVISGEPDHMITSVIGGHYATVINEHFFETLALNSRITLHVICHYGRDPHHITEAEYKAVARALRGAVEMDPRQTGIPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y143_SYNY3
Sequence: MSPIALNLLQSTPYQVGGSLAANHPSYSQREADRELLAQLRAGKFCYVFNCRQMGKSSLRVRAMHQLQQDGVVCVSIDITSLGTEADPQKWYNGIITQLYLGLPLAGKVALKPWLREREQLSPIQKLREFVETIILQTIGDRQIVIFIDEIDKVLSLPFSLDDFFSYIRFCYNQRADDHEYNRLSFALFGVATPSDLIDNKTQTPFNIGQAIALTGFTLTEALPLSAGLPVDEVSAREILGEILAWTGGQPFLTQKVCELVAEALQKGDLDCQSQTIATTIAQLIEEKIIRHWESNDEPVHFRTIGDRLLKDQARSGQLLGLYQEILHKGAIPADDSVEQTVLRLTGLVVKVKGQLRPYNPIYQAIFNAQWVSKELNKLRPYGTNLQAWINSNYQDSSRLLRGEALREALAWASSKNLSGVDYRYLNASQNQEQEASLAANQILTQANVKAKRMISFGIVVLMMSLGGSAIALSQAYFATLKQQRSQQGTELQRLGTSAQRQFTFDQIPGLVTALEAGNQLHHLVKADETLSQYPATSPLVSLQQILSQIAEKNVLTGHRDGVTSVAISSHKNLIASASRDGTVHLWTPQGEFLREFTGHTGSIYRVDFSPNGKIFATAGQDQTVKIWDLDGNLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVRLWHWRSGKTLAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRLWDLDGNLIRQFGLPEVAFFGVNWHPNGNLLAVAADDGTVRLWTPQGEIKATLSGHDEFVTRVVFTPDGKQLFSSSSNGSVIHWSTSGKMLKKYQGYPEAIFGLALASNGALLAIGAENNLVKVWDMSPKSDLVNLNLPAVLGAVAENAKTNTIALAMENEPLILFNTKNRSRQFLSDASQNLDRLKFSADGQWLLGQRGRQWQLWQLQTKSQLLKTWRTDISRVYDVDLRTTPTSPQWAIAMATGSGEVQLWQGTKNNQTSGNQSQGVPIELNDPIVLALGNSIQRKEPIRSVSLHPTLPQLAAGDEQGNLTLWNFDGTLIRSIVAHGDRLNQLQYSPNGKYLLSAGREGTAKIWSVEGQLLHTLKSDPLPIDQIAISPDSQWIATAASDGMVRLWDQQGNLRGEFTSTSGSLLGLDFNRQGQWLLAVAQNGDLQSWPVTPEKERLRQLVEQGCDWLRDYLATEKQPAQTYSLEFCQPTGN
What are the official names of this protein?
Uncharacterized WD repeat-containing protein slr0143.
Protein: RPAC2_CAEBR
Sequence: MGKKSEKKVVEETMEVDEQPAVEPEAVPEEEPEVEDEDLNVPKKKKMEILDPKSFEQDPSNLTLILYEEDHTIGNSIKHILSRMDEVEFCGYNVPHPLEDKILFRVQTKDGINALEVLVKAFESVEQVFSTIRGKFEAAYEKSIA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerases I and III subunit RPAC2, RNA polymerases I and III subunit AC2, AC19, DNA-directed RNA polymerase I subunit D.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CBIN_SALA4
Sequence: MKKTLMLLAMVVALVILPFFINHGGEYGGSDGEAESQIQAIAPQYKPWFQPLYEPASGEIESLLFTLQGSLGAAVIFYILGYCKGKQRRDDRA
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiN, Energy-coupling factor transporter probable substrate-capture protein CbiN, ECF transporter S component CbiN.
What is the protein family that this protein belongs to?
Belongs to the CbiN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACEK_STUS1
Sequence: MVQHELAAEIARQILLGFDDYREHFRLITEGARARFEQAQWQEAQRASAARISLYEEKVGETRRRLLASFDHADLLQVEAWPQIKSAYIELINPRFDDELSETWYNSIFCGLFSHDCISDGTMFIHTTRPAVRAHERLAQTRRYRPNGDLRGMLEQILRDYAFSVPYCDLPGDLQRLQTQLCETLPDWVCKDPELTVEVFVSVLYRNKGAYLIGRIFTCDEQWPLAIPLLHRDGQGIVADALITDEAEVSIIFSFTRSYFMVEVPIPAEFVGFLKRILPGKHIAELYSSIGFYKHGKSEFYRALIDHLANTDDRFVMAPGVRGMVMTVFTLPGFNTVFKLIKDRFSPIKSVNRANVIEKYRLVKSVDRVGRMADTQEFADFRFPKAKFEPECLAELLEVAPSTVEVQGDTVLVRHCWTERRMTPLNLYLENASEQQVREALEDYGLAIKQLAAANIFPGDMLLKNFGVTRHGRVVFYDYDEISFLTEVNFRHIPPPRYPEDEMASEPWYSVGPNDVFPEEFPRFLFADLGQRRLFASLHGELYDADYWKGLQDAIRQGKVIDVFPYRRKADRN
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
Protein: MUG89_SCHPO
Sequence: MPEALNENVSDTASNGPVAKTRAPPNTSFRQQRIKSWQPLLTPKIVLPLFFVLGIIFGPLGGGLLYASSIVQELVVDYTDCETLASYDEFSAVPSKKYTASFDQSGTIGFDKESTYWKLEKILDKDLDMDVNYCIIRFTVPSVLKAPIFIYYRLTNFFQNHRRYAKSVDEKQLQGVALTADEVKGGNCFPLEVNEDDKPYYPCGLIANSLFNDTFSSLRLLDDNSVYTFSTKNIAWASDKRRFLKTNYSPDDVAPPPNWVLRYPDGYTESNMPDLSTMENLQVWMRTAGLPTFSKLAMRNDNDDIFPGTYEIKIGLFFPVKSFDGTKSLVLTTRSVLGGKNPFLGIAYIVVSAVCVVLGTVFTLRHFIRPRKLADHRYLNWDSEENNLAPHLSDRP
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 89 protein.
What is the protein family that this protein belongs to?
Belongs to the CDC50/LEM3 family.
Protein: EFEO_SHIBS
Sequence: MTINFCRNALQLSVAALFSSAFMANAADVPQVKVTVTDKQCEPMTITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMTCGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDAIKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHRLEKALFGDNTTKGMDQYAEQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKISGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKYRTKDGFETYDKLTDADRNALKGPITAQAEDLAQLRGVLGLD
What is the function of this protein?
Involved in Fe(2+) uptake.  Could be an iron-binding and/or electron-transfer component (By similarity).
What are the official names of this protein?
Iron uptake system component EfeO.
What is the protein family that this protein belongs to?
Belongs to the EfeM/EfeO family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DSBB2_PSEF5
Sequence: MSLAGSRLLFSLVFLVGALASWAAFNLQTGGGLESCSLWSVQRLLLLALGGVNLLAVIQGPGRVGRAVYWGLNLLLGLLGVVTAGRHVLLQNIPSEQLLACLPDMSFMLRQLSWWQALKLTFMGTSDCAEVTWTLLDMSLPEWSLLFFVIMLIFSGYRLWRQLRGARKAVALP
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B 2, Disulfide oxidoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ECH17_MYCTA
Sequence: MAAVTPTVPEFVNVVVSDGSQDAGLAMLLLSRPPTNAMTRQVYREVVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARIRQQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLIPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYDAAAAWARRFLDGPPHALAAAKAGISDVYELAPAERIAAERRRYVEVFAAGQGGGSKGDRGGR
What is the function of this protein?
Could possibly oxidize fatty acids using specific components.
What are the official names of this protein?
Probable enoyl-CoA hydratase EchA17.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.