PharMolix/UniProtQA huggingface dataset:
Protein: YLMG2_ARATH
Sequence: MEASANEPAMKSLKSNPSGPIPNFFVSLSSAFTQTPLVRSNKPNLLLLPPVADSVKLIQDFHQSLISATEKFKGFLHSLASKNPLFQEAVRLSSEFHILCDEIRLRNTTRVRFAMSNHGFAAVLPGDSVAGLVVANGLINFLNIYNTILVVRLVLTWFPSAPPAIVNPLSTLCDPYLNIFRGFIPPLGGLDLSPILAFLVLNAFTSSAMALPCELPSADGAVSPASSETKWVRRRRLSSHKDHRPSSASMT
What is the function of this protein?
Not required for the biogenesis and accumulation of native cytochrome b6 in the thylakoid membrane.  Not functionally involved in the pathway for covalent binding of the c-type heme to cytochrome b6.
What are the official names of this protein?
YlmG homolog protein 2, chloroplastic, AtYLMG2, YGGT family protein YLMG2.
What is the protein family that this protein belongs to?
Belongs to the YggT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYH_METTH
Sequence: MDISRPRGTRDFLFAEMRNRKEVEGVLRRTFETYGYHEIKTPIFEELKLFTVKSGEEVVNQIYHFTDKGGRELALRPELTAPVARLYMNEMQKKPKPIKMYYFGSCFRYERPQAGRFRQFWQFGCELIGGRSPLAEAEVISLASESLHELGLDGFEVHIGHLGILRGILGREEIPSELQDRIMGVIDKGDVEELEALLGEVEVSGESRELLMKLIGTQGGPEVLDDVEEYLGGYSESLEALEEFRELVETLHYFGVDDYHVNLGIARGLDYYTGIVFEIYVPELGAQKQICGGGTYNLVETFGGERVESTGFAFGFDRLMNALGMDEENMRMVDVFVIPIQDSTVPEAIRITQELRAAGVSADLEVSGRKLRKALSHADNLGARFAVLTGEREIQDGKVTVKDMERNSQETLPRDEMVDKIKGRC
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNS1D_RATTI
Sequence: MGLEKSFILFSLLVLVLGWVQPSLGRKPSVQDFKRQHMDPGSPPNSRPTICNQMMKRRGITKDSCKPVNTFLHESGQRVQAICSQRQMTCKTSSRKNCHKSSSTLHITDCNLKGSSKYPNCDYTTTNRQKHIIIACEGNPLVPVHYDASV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic delta-type, RNase 1 delta.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYDE1_MOUSE
Sequence: MAEPLLRKTFSRLRGREKLPRKKSEAKDRGHPAQRSEPKPPEPEPRVLEGSQAGAEVPPSPETPRSPTRGAYLQSLEPSSRRWVLGGAKPPEEISLGPRTPSSGEPAGEIWYNPIPEEDPRPPAPEPLGSQLASSEPEGPNIQGAAPTSPPTKTSRTKSPGPARRLSMKMKKLPELRRRLSLRSTRTGRDRERTAPAGSVISRYRLDSSVGTPGQASVAGGSRSPRGGYLSDGDSPERPGGPPSPTAFRPYEVGPSARTPPAALWGRLSLHLYGLGGLRPSPGATPRDLCCLLQVDGVARARTGPLRSGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTIFRGCQAQQLAVRLEPQGFLYAKLTLSEQQEAPATAEPRVFGLPLQLLVEREQSPGQVPLIIRKCVGQIECRGLRVVGLYRLCGSAAVKKELRDAFEQDSAAVCLSEDVYPDINVITGILKDYLRELPTPLITQPLYQVVLEAMAQGHPSRASLGPEGTRGLLRCLPDVERATLTLLLDHLRLVSSFHTHNRMTPQNXAVCFGPVLLPARQTPSRPRLRSSGPGVTSAVDFKRHIEVLHYLLQSWPDTRRPSDTPDGAVAPYLRPKRQPPLHLPLAGPEVVTRPRGRGGPESPPSNRYAGDWSVCGGDLLPCGRDFLSGPDYDHVTGSDSEEDDDETGEPRGTTDFEDEFDAPFNPHLNLKDFDALILDLERELSKQINVCL
What is the function of this protein?
GTPase activator for the Rho-type GTPases.  As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration.  It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1.
What are the official names of this protein?
Rho GTPase-activating protein SYDE1, Synapse defective protein 1 homolog 1, Protein syd-1 homolog 1.
Protein: MURB_SHIFL
Sequence: MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQHATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLAQFPTAPNYPQAGGSVKLAAGWLIDQCQLKGMQMGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGEVSAVETIS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANE_ECOK1
Sequence: MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTPETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: TF2B_SULAC
Sequence: MVEQSKVPSSSLCPPDKIIFDEERGEYICTETGEVIEERIIDQGPEWRAFTPEEKEKRSRVGGPLNQTIHDMGISTVIDWKDKDAMGRSLDPKRRLEVLRWRKWQIRTRIQSSIDRNLAQAMNELERIGNLLNLPKAVKDEAALIYRKAVEKGLVRGRSIESVVAASIYAACRRMKMARTLDEIAQFTKANRKEVARCYRLILRELDIEVPVSDPKDYVTRIGTLLSLSGITMKHAAEIIEKAKNSGLTAGKDPAGLAAAAIYIAALLNDERRTQKEIAQVAGVTEVTVRNRYKELTQELKIQIPSQ
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: RNF11_HUMAN
Sequence: MGNCLKSPTSDDISLLHESQSDRASFGEGTEPDQEPPPPYQEQVPVPVYHPTPSQTRLATQLTEEEQIRIAQRIGLIQHLPKGVYDPGRDGSEKKIRECVICMMDFVYGDPIRFLPCMHIYHLDCIDDWLMRSFTCPSCMEPVDAALLSSYETN
What is the function of this protein?
Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways.  Promotes the association of TNFAIP3 to RIPK1 after TNF stimulation.  TNFAIP3 deubiquitinates 'Lys-63' polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains.  This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B.  Recruits STAMBP to the E3 ubiquitin-ligase SMURF2 for ubiquitination, leading to its degradation by the 26S proteasome.
What are the official names of this protein?
RING finger protein 11.
What are the subcellular locations of this protein?
Early endosome. Recycling endosome. Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, when unphosphorylated, and nuclear, when phosphorylated by PKB/AKT1.
Protein: SRRB_STAAC
Sequence: MMSRLNSVVIKLWLTIILIVTTVLILLSIALITFMQYYFTQETENAIREDARRISSLVEQSHNKEEAIKYSQTLIENPGGLMIINNKHRQSTASLSNIKKQMLNEVVNNDHFDDVFDKGKSVTRNVTIKEKGSSQTYILLGYPTKAQKNSHSKYSGVFIYKDLKSIEDTNNAITIITIITAVIFLTITTVFAFFLSSRITKPLRRLRDQATRVSEGDYSYKPSVTTKDEIGQLSQAFNQMSTEIEEHVDALSTSKNIRDSLINSMVEGVLGINESRQIILSNKMANDIMDNIDEDAKAFLLRQIEDTFKSKQTEMRDLEMNARFFVVTTSYIDKIEQGGKSGVVVTVRDMTNEHNLDQMKKDFIANVSHELRTPISLLQGYTESIVDGIVTEPDEIKESLAIVLDESKRLNRLVNELLNVARMDAEGLSVNKEVQPIAALLDKMKIKYRQQADDLGLNMTFNYCKKRVWSYDMDRMDQVLTNLIDNASRYTKPGDEIAITCDENESEDILYIKDTGTGIAPEHLQQVFDRFYKVDAARTRGKQGTGLGLFICKMIIEEHGGSIDVKSELGKGTTFIIKLPKPE
What is the function of this protein?
Member of the two-component regulatory system SrrA/SrrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels as well as biofilm formation (PubMed:24222487).  Also plays an essential role in host-derived nitric oxide resistance by regulating hmp/flavohemoglobin, an enzyme that detoxifies nitric oxide by converting it to nitrate (PubMed:16859493, PubMed:24222487).  Functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to SrrA.  In turn, SrrA binds to the upstream promoter regions of the target genes to positively and negatively regulate their expression (Probable).
What are the official names of this protein?
Sensor protein SrrB, Staphylococcal respiratory response protein B.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRBM3_XENBM
Sequence: GIGSALAKAAKLIEGMV
What are the official names of this protein?
Caerulein precursor fragment-related peptide BM3, CPF-RP-BM3.
What are the subcellular locations of this protein?
Secreted.
Protein: SQOR_DICDI
Sequence: MFKSIMYALAVAPAVTSSSDKLPNGVVSASQLGSEKEKRKLKNVTKIVIVGGGAGGLSVASQLEHKFKNKGDIVIVEPSEKHYYQPLWTLVGGGIFSRKDSEKDEKDFIPKGATWVKDSVTVFKPEENIVLTKDGKEIDYDYLVVSTGLELYWDRVKGLKENLGKNGVTSNYSYDSCEKTFEFIKSLKPGNVAIFTVPTTGVKCGGAPQKILWLCDDYLRKHGIRDKVRLDFNSAGASMFPVKKYSEVLDKMAKERGVNQNFAHNLVEIKGDSKEAVFETPQGNKTVKYDMIHVVPPMGPHSVIKNSPLADPATGFVNVDKGTLQHVKYDNVFSLGDTSNLPTSKTAAAITSQAPILVGNLINHKLGLPLNHKYDGYTSCPITTSYSKIILAEFKYGFEVDESLPFDQSKESYFPMFLKKYVFPTAYWEGMLKGRWFGKNTLFNPIKTPEIN
What is the function of this protein?
Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone.
What are the official names of this protein?
Sulfide:quinone oxidoreductase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SQRD family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GLND_BRUO2
Sequence: MSAHDLKLEEIVNAETLRRKLNELADTADESYTSLPMRKVVLQTLKDALASGRANAEDMLMKDGGGTLCAKRLCYLMDTLIDILFEFATTRAYPTRNPSKAENMALVAVGGYGRGGLAQGSDIDLLFLLPYKQTPWGEQVVEYTLYMLWDMGLKVGHSTRNIDECIRLAREDMTIRTALLDARFLTGDKDLFRTLEIRFEEEIVKGTEPEFIQAKLAERDARHRKAGETRYLVEPNVKEGKGGQRDLHTLFWITKYFYRVKTKEELVKLGVLSRAELKLFNKAEDFLWAVRCHMHFATLKAEERLSFDIQPEIAQRLGYTAHPGQNYVERFIKHYFLVAKDVGDLTRIICAALEEQQAKHVPGFNRIFLTFSRRKRKLSDDGAFISENHRINIARPDIFRQDPVNMIRLFHLADRHGLEFHPEAMQSLTRSLKLINADLRENPEANRLFLEILTSPRNPELILRRMNESGVLGKFIPDFGKIVAMMQFNMYHHYTVDEHLLRCIAVLSEIEHGELKTEHPLSNHLITTIKRDRNLLYVTLLLHDIAKGRPEDHSIAGARIARRLCPRFGLTPSETETVEWLVREHLTMSMVAQSRDLNDRKTIIDFADTVQTMERLKLLLILTVCDIKAVGPGIWNGWKGQLLRTLFYETELVLTGGFSELSRAARDKQAREALAERLSDWPKEERDAYLALPYTNYFLTVSLDDQVRHAHFIRDADQQGRALVTMAKPHAFEAVTEITVLAPDHPRLLSVITGACAAAGGNIVDAQIFTTSDGRALDTILISREFDTDDDERRQAERVGKVIEDVLSGKAHLPDMLAKRTKPKKAARAFKVEPRVEINNTLSNKFTVIEVEGLDRPGLLSELTGLISDLSLDIASAHITTFGEKVIDSFYVTDLVGHKISNATRQGNIKRKLLALLGAENGARTNGRSPQAAA
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: RL331_STRPC
Sequence: MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTLHVET
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: UGPC_YERE8
Sequence: MACLKLQAVTKSYDGVTPVIKQIDLDVTDGEFIVMVGPSGCGKSTLLRMVAGLERTTSGDIYIDNLRVTDMEPKDRGIAMVFQNYALYPHMSVFDNMAYGLKIRGFGKEQIRQRVDEAARILELEPLLKRKPRELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVIVMNKGVAEQIGTPSEVYQRPATLFVASFIGSPAMNLLAGTVSPDGRAFILADGMTLPLEVPRPQWADRRLTLGIRPEHIQQRVSQQKTSAQGVPMTLLTLELLGADNLAHGQWGGQSVIARLSHEEMPTAGSVLYLYLPPAALHFFDSESGLRMES
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNPA_CAMJE
Sequence: MKNFDKFSTNEEFSSVYKVGKKWHCEGVIIFYLNSYEKKIAVVASKKVGKAVVRNRSKRILRALFAKFERYLQDGKYIFVAKNEITELSFSRLEKNLKWGLKKLECFK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: QUEC_POLNA
Sequence: MPAPVSRAHTSALVLFSGGQDSTTCLAQALAKYERVETIAFDYGQRHKVELQARLNVLRELKSQFPQWAAKLGEDHLLDLAVLGQVSDCSLTRDVAFKMESSGLPNTFVPGRNLLFLTLAAALAYRRDLQVLVTGVCETDFSGYPDCRDDTMKAMQLALSLGMDKRFLIETPLMWIDKADTWALAESLGGQPLVELIIEHTHTCYLGDRIHRHAWGYGCGQCPACELRARGYARYAEAA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: CLPP_EDWI9
Sequence: MSYSDQRELAPHMALVPMVVEQTSRGERSYDIFSRLLKERIIFLTGQVEDHMANLIVAQMLFLEAENPEKDIHLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQACSMGSFLLAAGAQGKRFCLPNSRVMIHQPLGGFQGQATDIEIHAKEILSIKARMNTLMAKHSGQPIEVIERDTERDRFMSAQDAVEYGLVDAVLTQRA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E13B_HORVU
Sequence: MARKDVASMFAAALFIGAFAAVPTSVQSIGVCYGVIGNNLPSRSDVVQLYRSKGINGMRIYFADGQALSALRNSGIGLILDIGNDQLANIAASTSNAASWVQNNVRPYYPAVNIKYIAAGNEVQGGATQSILPAMRNLNAALSAAGLGAIKVSTSIRFDEVANSFPPSAGVFKNAYMTDVARLLASTGAPLLANVYPYFAYRDNPGSISLNYATFQPGTTVRDQNNGLTYTSLFDAMVDAVYAALEKAGAPAVKVVVSESGWPSAGGFAASAGNARTYNQGLINHVGGGTPKKREALETYIFAMFNENQKTGDATERSFGLFNPDKSPAYNIQF
What is the function of this protein?
May provide a degree of protection against microbial invasion of germinated barley grain through its ability to degrade fungal cell wall polysaccharides (PubMed:1899089).  Hydrolyzes laminarin in vitro (PubMed:8514770).
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase GII, (1->3)-beta-glucan endohydrolase GII, (1->3)-beta-glucanase isoenzyme GII, Beta-1,3-endoglucanase GII.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
Protein: IF2_PSEPF
Sequence: MTQVTVKQLADEVKTPVERLLQQMREAGLPHTAAEENVTDSEKQSLLTHLKSSHKAKVEEPRKITLQRKTTSTLRVAGSKSISVEVRKKKVFVQRSPEEIEAERKRELDERRAVENAARQKAEEEARVRAEEEARRQPAAPSAPAEAVAAPAPVAEPVREAAPVVAAAPAADTRKRDEQRRPDKPRADDNNRRGGDGERKNAPHRASVKEKAPAPRVAPRTTDEESDGFRRGGRGKAKLKKRNAHGFQSPTGPVVREVKIGETITVGDLAQQMSVKAAEIIKFMFKLGTPATINQVLDQETAQLVAEELGHKVTLVSDTALEDSLAESLKFEGEAVPRAPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETERGMVTFLDTPGHAAFTAMRARGAKATDIVILVVAADDGVMPQTIEAVQHAVAAGVPLVVAVNKIDKPGADLDRIRSELSAHGVTSEDWGGDTPFVPVSAKMGTGVDELLEAVLLQAEVLELTATPSAPGRGVVVESRLDKGRGPVATVLVQDGTLRQGDMVLVGSNYGRVRAMLDENGKPIKEAGPAIPVEILGLDGTPDAGDEMSVVADEKKAREVALFRQGKFREVKLARAHAGKLENIFESMGQEEKKTLNIVLKSDVRGSLEALQGALNGLGNDEVQVRVVGGGVGGITESDANLALASNAVLFGFNVRADAGARKIVEQEGLDMRYYNVIYDIIEDVKKALTGMLGSDVRENILGVAEVRDVFRSPKFGAIAGCMVIEGTVHRNRPIRVLREDIVIFEGELESLRRFKDDASEVRAGMECGIGVKSYNDVKVGDKIEVFEKVQVARSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RP147_VACCC
Sequence: MAVISKVTYSLYDQKEINATDIIISHVKNDDDIGTVKDGRLGAMDGALCKTCGKTELECFGHWGKVSIYKTHIVKPEFISEIIRLLNHICIHCGLLRSREPYSDDINLKELSGHALRRLKDKILSKKKSCWNSECMQPYQKITFSKKKVCFVNKLDDINVPNSLIYQKLISIHEKFWPLLEIHQYPANLFYTDYFPIPPLIIRPAISFWIDSIPKETNELTYLLGMIVKNCNLNADEQVIQKAVIEYDDIKIISNNTSSINLSYITSGKNNMIRSYIVARRKDQTARSVIGPSTSITVNEVGMPAYIRNTLTEKIFVNAFTVDKVKQLLASNQVKFYFNKRLNQLTRIRQGKFIKNKIHLLPGDWVEVAVQEYTSIIFGRQPSLHRYNVIASSIRATEGDTIKISPGIANSQNADFDGDEEWMILEQNPKAVIEQSILMYPTTLLKHDIHGAPVYGSIQDEIVAAYSLFRIQDLCLDEVLNILGKYGRKFDPKGKCKFSGKDIYTYLIGEKINYPGLLKDGEIIANDVDSNFVVAMRHLSLAGLLSDHKSNVEGINFIIKSSYVFKRYLSIYGFGVTFKDLRPNSTFTNKLEAINVEKIELIKEAYAKYLNDVRDGKIVPLSKALEADYVESMLSNLTNLNIREIEEHMRQTLIDDPDNNLLKMAKAGYKVNPTELMYILGTYGQQRIDGEPAETRVLGRVLPYYLPDSKDPEGRGYILNSLTKGLTGSQYYFSMLVARSQSTDIVCETSRTGTLARKIIKKMEDMVVDGYGQVVIGNTLIKYAANYTKILGSVCKPVDLIYPDESMTWYLEISALWNKIKQGFVYSQKQKLAKKTLAPFNFLVFVKPTTEDNAIKVKDLYDMIHNVIDDVREKYFFTVSNIDFMEYIFLTHLNPSRIRITKETAITIFEKFYEKLNYTLGGGTPIGIISAQVLSEKFTQQALSSFHTTEKSGAVKQKLGFNEFNNLTNLSKNKTEIITLVSDDISKLQSVKINFEFVCLGELNPNITLRKETDRYVVDIIVNRLYIKRAEITELVVEYMIERFISFSVIVKEWGMETFIEDEDNIRFTVYLNFVEPEELNLSKFMMVLPGAANKGKISKFKIPISDYTGYDDFNQTKKLNKMTVELMNLKELGSFDLENVNVYPGVWNTYDIFGIEAAREYLCEAMLNTYGEGFDYLYQPCDLLASLLCASYEPESVNKFKFGAASTLKRATFGDNKALLNAALHKKSEPINDNSSCHFFSKVPNIGTGYYKYFIDLGLLMRMERKLSDKISSQKIKEMEETEDF
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG133, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 147 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 147 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.
Protein: PUR7_THESQ
Sequence: MNYEGKTKIVKVTGDYALLEFKDDITAGDGLKHDVLTGKGSICAETTAILMKYLSEKDIKTHLVEYIPPRTLKVIPLKMFPLEVVVRLKKAGSFVRRYGGAEGEDLPVPLVEFFIKDDERHDPMVCVDHLEILGIATKKQAEKMKEAAVKITLALKEFFERANFELWDIKYEFGLDKDGNVVLGDEISPDTFRLRNKGEIFDKDVYRRDLGDPLKKYREVLELCRSLNSQ
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RL36_RHOPB
Sequence: MKVRNSLKSLRSRHRDNRLVRRKGRVYVINKVQRRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SECA_BRUSI
Sequence: MVSFGGLARKIFGSSNDRRVKTLRQRAEQITALEKNYENLTDEQLQAKTAEFRAALAEGKSLDSLLPDAFATAREAAKRVLGMRPFDVQLIGGMVLHERGIAEMRTGEGKTLMATLPVYLNALEGKGVHVVTVNDYLATRDAETMGRLYNFLGLTVGVIKHGLDDDERRAAYACDITYGTNNELGFDYLRDNMKYERAQMVQRPHNYAIVDEVDSILIDEARTPLIISGPLEDRSDFYNLIDTFIPPLAEEDYEVDEKQKTAIFTEVGTEKVEKLLEAAGHLKGESLYDIENVAVVHHLNNALRAHKLFQRDKDYIVRNDEIVIIDEFTGRMMPGRRYSEGLHQALEAKEHVTIQPENQTLASITFQNYFRMYNKLSGMTGTAATEAEEFGNIYGLEVLEIPTNLPVQRIDEDDEVYRTVEEKYRAIVRDIRASHEKGQPILVGTTSIEKSEQLAERLRREGIKGFQVLNARYHEQEAYIIAQAGVPGAVTIATNMAGRGTDIQLGGNLEMRVRQELSDVPEGPEREEKIAAIKADIAQLKEKALAAGGLYVLATERHESRRIDNQLRGRSGRQGDPGRSKFFLSLQDDLMRIFGSDRMDGMLQKLGLKEDEAIVHPWINKALEKAQKKVEARNFEIRKNLLKYDDVMNDQRKVIFEQRLEMMDEEDLTETVAEMRHEVIEDMVILRIPKDAYAEKWDIAGLKQDIASKLNLDLPVEEWAKEEGIAEEEFENRIKEAADKAAAEKAERFGPQIMTYVEKSVIMQSLDNLWREHLVNLDHLRSVVGFRGYAQRDPLNEYKTEAFELFQTMLANLREVVISQLMRVEIVREAPPEPQLPPMAGLHIDGTTGENDFDEAIWAEHQHDDRIVPPAQRDPADPRTWGKVSRNEPCPCGSGKKYKHCHGAFE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: DEOC_DESHY
Sequence: MRTMNLAGMIDHTFLKPEATEKDIVNLCHEAKQHKFATVCINPAYICTAAKLLHGSGVGVATVIGFPLGATMTEIKVQEIFAAKAHGAREVDIVINIGWAKSGNWEAVAKDITRAVEAAHCCGVTIKVIIETSLLTEEEKQKAAEIVKASGADYIKTSTGFAGGGATVEDVRNLKAWVGQSVKVKASGGIRSRETALQMVEAGADRLGTSSGVQIITV
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_SHEFN
Sequence: MNFENLLIEVGTEELPPKALRTLAESFLTSFTDELTKADLPFESAVWYAAPRRLAINVLGLALAQADKVVEKRGPAVSSAFDADGNPTKAAQGWARGNGITVEQAERLVTDKGEWLVHQAKVVGVETKSLIADMAQRALDKLPIPKPMRWGNNKTQFIRPVHTVTMLLGSELVAGELLGITSNRIIRGHRFMGKASFELDHADNYLAALKEQGKVLADYELRKSLIKADAEAAAAKLGGIADIQDGLLEEVASLVEWPIVLTASFEEKFLNVPSEALVYTMKGDQKYFPVFDKAGKLLPNFIFVTNIESKDPQQIISGNEKVVRPRLADAEFFFNTDKKNTLESRIASLETVVFQKQLGTLKARVERISELAGFIATQMNNNGVETNSVDASRAGLLSKTDLMTNMVMEFTDTQGTMGMHYARLDGETEAVAIALEEQYKPKFSGDTVPTATVSCAVALAEKLDTLVGIFGIGQAPKGAADPFALRRAAIGILRVIVENKLPLDLVELIAKAQALHATNITNTNTSDDVLEFLLARFRAWYQDKGIQVDVILAVLARRPTKPADFDSRVKAVSHFRGLEASTALAAANKRVSNILAKVEGELPATINSALLTEPAEKALADKLVQLQPQLAPLFADGNYQQALTLLADLRENVDQFFEDVMVMADDEALKNNRLALLTNLREQFLHVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANK3_HUMAN
Sequence: MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLCATGGGAYKFEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLDDPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNNIGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPNFS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis.
What are the official names of this protein?
Pantothenate kinase 3, hPanK3, Pantothenic acid kinase 3.
What is the protein family that this protein belongs to?
Belongs to the type II pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.