PharMolix/UniProtQA huggingface dataset:
Protein: RS19_CHLCH
Sequence: MPRSLKKGPFIDIKLEKRILEMNSKGEKKVVKTWSRSSMISPDFVGHTVAVHNGKSHVPVYVGDNMVGHKLGEFAPTRNYRGHAGGKSEKGGSAPRKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PANB_STUS1
Sequence: MPDVTLTTLQGLKQKGEKIVMLTCYDATFAKTACDAGVEMLLIGDSLGMVLQGHDSTLPVTVADMAYHTASVKRGNRGAMIVADLPFMANATTEQTLNNSALLMQAGAHMIKLEGTAWLAESIRLLADRGIPVCAHMGLTPQAVNLFGGYKVQGREEAQAQQMLEDAKSLEAAGAAMLLLECVPSELAARITRAVQIPVIGIGAGSDTDGQVLVLHDMLGLSLSGRVPKFVKNFMREHGDIPAAIAGYVKAVKAVEFPAAEHGFSA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
Protein: CTTB2_SHEEP
Sequence: MATDGASCEPDFSRAPEDAAGAPAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGASDKEKKPVCTNPLSILEAVMAHCRKMQERMSTQLAAAESRQKKLEMEKLQLQALEQEHKKLAARLEEERGKNKHVVLMLVKECKQLSGKVLEEAQKLEEVMAKLEEEKKKTSALEEELATEKRRSAEMEAQMEKQLSEFDTEREQLRAKLHREEAHTTDLKEEIDKMKKMIEQLKRGNDSKPSLSLPRKTKDRRLVSISVATEGPMTRSVACQTDLVTETAEPLKKLPLTVPVKPAAGSPLVSASAKGNACASAASVRPGIERQVSHGDLIGSSLPTVPPPSTDRIEENGPSTGSTPDLTSSPTALPSTVSPASGHTPTPPPHSLHSPCANAPLHPGLNPRIQAARFRFQGSNANDPDQNGNTTQSPPSRDVSPTSRDTLVAKQLARNTVTQALSRFTSPPAGAPPRPGAPPTGDVGTYPPVGRTSLKTPGGARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVIMDSSRASSTGIKADNKTVASSPSSLPQGNRVINEENLSKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGAWPAETPGLNQPACSESSLVIPTTTAFRSSINPVSASSRRAGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFKCVELLIAYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGWTPIHAAVDTGNVDSLKLLMYHGAPAHGNKLQEEPGLAIFDLDQEEHHEGTSKPVVPADLINHADSEGWTAAHIAASKGFKNCLEVLCRHGGLEPERRDKCNRTAHDVATDDCKHLLENLNALKIPLRISVGEIEPGNYGADDFECENTICALNIRKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDMTFNSTTDSSIGLSASSVRSITLGSVPWSAGQSFTQSPWDFMRTNKAEQVTVLLSGPQEGCLSSVTYASMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIAHQLALCLKHRQMAAGFPCEIVRAEVDADFSKEQLVDLFISSACLIPVKQSPANKKIIIILENLEKSSLSELLGDFLGPLENHSTESPCTFQKGNGMSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDSEPMQGLLQRFLRRKVVNKFRGQVPSPCDPVCKTVDWALAVWRQLNSCLARLGTPEALLGPKYFLSCPVIPGHAQATVKWMSKLWNAVIAPRVQEAILSRASVKRQPGLGQTTKNPSQGQQAVVRAALSILLNKAVLHGCPLQRAELDQHTADFKGGSFPLSIVSSYSSCSKKRESGAWRKVSTSPRKKSGRFSSPTWNKPDLSEEGIKSNTILQLNCNRNASLSNQKSLENDLSLTLNLDQRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRRFDSSGNNPVFSATVNNPRMPVSQKEVSPLSSHQMTERSNSKSKTESGVSRVKSFLPVPRSKVTQCSQNTKRSSSSSNTRQIEINNNSRDLEPTQK
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.
Protein: MAO1_YERPS
Sequence: MELEYESKRPLYIPYAGPILLEFPLLNKGSAFTNDERNHFNLHGLLPEAVETIEEQAERAYRQYQDFKNDDDKHIYLRNIQDTNETLFYRLLEAHLSEMMPIIYTPTVGEACEHFSDIYRRARGLFISYPNREHIDDMLQNATKQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNPQRLNDPLYMGWRHPRISGDEYYAFVDEFIQAVKRRWPNVLLQFEDFAQKNATPLLNRYRDELCCFNDDIQGTAAVTLGSLIAASHAAGSQLRDQTVTFLGAGSAGCGIAEQIIAQMMSEGLSEIQARARIFMVDRFGLLTDKLPNLLDFQSKLVQKSDDLHHWNLHNDAISLLDVVRNAKPTVLIGVSGQPGLFTEELIREMHSHCARPIVMPLSNPTSRVEARPEDIINWTDGAALVATGSPFPPVSYKEKLYPIAQCNNSYIFPGIGLGVLASGASRVTDGMLMAASRALAESSPLARHGEGALLPNIDDIQAVSKAIAMRVGQAAQLQGVAIVTSEEALSKAIEHNYWQPQYRSYKRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: SYA_METAR
Sequence: MDDKEIKKLMKPEFAKNYEKYYPVQTLTAMGYHRRVCKKCGRGFWTQVERDFCDEAECSGGYRFIGESLTRKKFEYKEAWDTYVKTFEQWGYVPLERYPTVCRWYEDLYFVAAGINDFQPYVVSGEIEPPARAVLEPQFCLRFNDIDNVGITGRHYTGFIMVGQHTFNTPEKHVYFKEEGIGQIQHFLTQGLGIPAHEIVFHEDVWAGGGNFGPSIEYFSRGLELGNQVYMQYEQTPDGGFKELRTKVIDMGAGLERWAWFSQGCPMSYDATFPKTMEFIYNKTGYRADPVFHAKFAKYAGILNVEEIEDVGSAWNDVAKSMEMDLGELKDMVYKIRAQYVLADHTRSLLVAIHDGALPSNVGGGYNLRNLLRRCWSLIDQYQWDIDLNDIFRSHIDEFGSWYTELKDYGSLFDIIDVERKRYEESRRKSKDIIKRMVKAKETLTADKLVELYDSQGISPELIKEAKPDVVIPEDFYARVQARHDAKATRKIEVNETQGLPKTEPMYYEKPREFKFEANVVKLLTPTKLVLDRTLFYPLGGGQAGDTGFVNGIKVKDVYKQDGVIIHVLESPMPPDTTKVIGEVDEARRRILAAHHSATHIVNYAARKVLGDHVWQAGAEKTPEKARLDITHYESLTFQQLQEIERVANDLAMKQIPVVVREMSRTEAEMEYSMRIYQGGAVPGKILRIIVIDGYDVEACGGIHVDNTSKVGFIKMLSSERIQDGVVRLEFKSLDNAVSEIQHHESILREVSDLWGVGYDDIPKTAQRFFNEWKELGKKNKELQAELVQQTIAAALGKPGDTVDVVVTGADFGTLMKAVGSFKKEFKGRTVIFRGDNFAYGYSDLINVKEKLAEGYVNVDGSEHEAKAFKAKPKA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEOB_LEPBP
Sequence: MKEKNIYLVGNPNCGKTTLFNQLTGLNQKTGNFSGVTVEKKEGVVYLPNLELKITDLPGTYGLGGIAEDKKIAYEVLLKRKENEVVIYVLDALNLERGLQFLLQIIDMGVPTLVVLTMKDVLEKKRIQLDLKKLKHSLGLEIVLVNAKSGEGISELKTLLSKEESYRKQKRLWTWGSKEESFLTSLKQKLKITTNEAEFFLSQALKFLNHDPHLQDSRYLNQFPNETKQFLTKELESKPLQFAYQEEMIHRSILIKKIISETIHYPIAIQGSWEERLDRIFLHPILGFVCFFLLMGLLFQSLFSFAEIPMDLIEEGITGLQETIGNVLSDGPLKSLLIEGILGGVGSVVVFVPQIALLFLFIGILEESGYLARASFLMDRLMGKFGLSGKSFIPLLSSAACAVPAILGTRTIENKSDRFTTIMVSPLIMCSARYPVYILIVGTVFSYPPIFGIFNVQGFVLFSMFFLGMIVSFTFALIFRKTVFKENASYFVMELPRYNLPSFKSLFFTVYGKVKSFLATAGQIILYISVILWFLSHFPAEYKDNVWKTSPIETSYIGRVGKVMEPAIEPLGFDWKIGISILTSFAAREVMVSTLAVLYGSEEEGEESESLRETLRADKKPDGSPVWTPLTGLSLLLFFAFASQCMSTLAVTKKETGSLLWPTVQFLYMTTLAIFTSFLVFQLGKILGFV
What is the function of this protein?
Probable transporter of a GTP-driven Fe(2+) uptake system.
What are the official names of this protein?
Fe(2+) transporter FeoB, Ferrous iron transport protein B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HFQ_SALPA
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGASNNYHHGSNAQGSTAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: HSCA_VIBC1
Sequence: MALLQIAEPGQSSAPHEHKLAAGIDLGTTNSLVASVRSGDAKTLTDDQGRSILPSVVNYAQDTALVGYEAKAKAEQEPENTIISVKRLIGRSLKDIQARYPSLPYQFKESDNGLPILQTAQGDKNPIEVSADILKSLGKRAEETLGGELAGVVITVPAYFDDAQRAGTKDAAKLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSKGVFEVLATGGDSALGGDDFDHLLADYLMEQAGLEAPLSAEKNRALLNIATATKIAFSEQDCVDVDVFGWKGAVTREQFEELIRPLVKKTLMSCRRALKDADVDAEDVLEAVMVGGSTRTLLVREMVGEFFGRTPLTSINPDEVVAIGAGIQADILAGNKPDSEMLLLDVIPLSLGIETMGGLVEKIIPRNTTIPVARAQEFTTFKDGQTAMSVHTVQGEREMVDDCRSLARFSLKGIPPMVAGAAHIRVTYQVDADGLLSVTAMEKSTGVQAEIQVKPSYGLSDDEVANMLRDSMTYAKEDMQARALAEQRVEADRVIEGLIAAMQADGDELLSDQEKQDLVKVIEALIELRNGEDADAIEQGIKDTDKASQDFASRRMDKSIRAALSGQSVNDI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PBN1_ASPFU
Sequence: MRRRITFVQRPESPFHVDQAVLTSDALSITHLDAAREERATFGFDELPAEIWQVLKSSHELHIRWATERPYEIGAPFSSRISPGLHVYYTPGTARETGVGLCSLLKTVFDESLECQSLRYYSRLPSLQNLVAFIQHKFCDRSDEKCVHHAESILSADSVDVNYDSISHALTVSGYWSTSPGQGWTEQIRKHAADTHQVEVGLLGVESATEPEELKMEPTLFSFPSRHHPLPADATYTVSFPAPTGLHPTLTISMPRASLRRPPAPPDATCALHTYLTLPSWIFGDKYQLSTTDRLFLSSHNLAALRAVAGETDLEAPDWVVSRWGSNWLLELATPLRPDTSPEEWNASIPLHLRYLTPSESGYRSAAVPWPIVFWACTAEDGTKMGVNPFDRVNLGWEGLFGARTMFYQLHPAPAEGKDRLVEELDVPVLRLREDAGFFQSKTIELGTVVVVGLGLLWVLWKLGLVLWIAGTGRSTRAQKRTDKHRKAE
What is the function of this protein?
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum.  Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.  Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity).
What are the official names of this protein?
Protein pbn1.
What is the protein family that this protein belongs to?
Belongs to the PIGX family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: GLPF_BACSU
Sequence: MTAFWGEVIGTMLLIIFGAGVCAGVNLKKSLSFQSGWIVVVFGWGLGVAMAAYAVGGISGAHLNPALTIALAFVGDFPWKEVPVYIAAQMIGAIIGAVIIYLHYLPHWKSTDDPAAKLGVFSTGPSIPHTFANVLSEVIGTFVLVLGILAIGANQFTEGLNPLIVGFLIVAIGISLGGTTGYAINPARDLGPRIAHAFLPIPGKGSSNWKYAWVPVVGPILGGSFGGVFYNAAFKGHITSSFWIVSVILVVVLLGLYVYTKSHSAKTLSNSKYI
What is the function of this protein?
Mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism.
What are the official names of this protein?
Glycerol uptake facilitator protein.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 5MP1_HUMAN
Sequence: MNKHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRYKYLEKAFEDEMKKLLLFLKAFSETEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGIAASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCIMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN
What is the function of this protein?
Translation initiation regulator which represses non-AUG initiated translation and repeat-associated non-AUG (RAN) initiated translation by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function (PubMed:21745818, PubMed:28981728, PubMed:34260931, PubMed:29470543).  Increases the accuracy of translation initiation by impeding EIF5-dependent translation from non-AUG codons by competing with it for interaction with EIF2S2 within the 43S pre-initiation complex (PIC) in an EIF3C-binding dependent manner (PubMed:21745818, PubMed:28981728, PubMed:34260931).
What are the official names of this protein?
eIF5-mimic protein 1, Basic leucine zipper and W2 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the BZW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPT_STRPZ
Sequence: MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEVFALTILKPEMEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQGGDITLGSSNYKLDPEAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTSQPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALEVTFLGRNVHPGTAKDQMINALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEEARASYIIRDFEEASFEARKVKVENIAQSMNAHLGTKRVLVELNDQYYNMKKVIEKDMTAIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQTMERAVDVIIGLVCKA
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_PECCP
Sequence: MLTIGTALRADATRVMLLGSGELGKEVAIECQRLGIEVIAVDRYADAPAMQIAHRSHVINMLDGDALKALVEAERPDYIVPEIEAIATDMLVTLEKQGHHVVPCAEATRLTMNREGIRRLAAETLGVPTSTYRFADSEESFRQAVEAIGYPCIVKPVMSSSGKGQSLIRSAEQLDKAWNYAQQGGRAGGGRVIVEGLVNFDFEITLLTVHAVDGIHFCAPIGHRQEDGDYRESWQPQQMSALAQERAQKMASDVVKALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTMISQDLSEFALHVRAFLGLPIGAVRQYGASASAVILPELESNNVRYQGLESALLPHTQIRLFGKPDIGGKRRMGVALASAETTEDAVEIAKRVAAGVTVSG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: MURA1_STAAM
Sequence: MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATKTLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSIHLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAGTLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTANGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDRGYVDLHGKLKQLGADIERIND
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_MYCMS
Sequence: MKNNYKSLVIVGSQWGDEGKGKITDYFSQKADVVVRFAGGDNAGHMIEFNNKRHKVTIIPSGVFNPKVKNIIGNGTVINLKSLVNEIKRLNESNISTDNVFVSDRAHLIFDWHALIDQLQEENRKENKIGTTKRGIGPTYADKAARYGIRICDFQNPNFKEILKENLDYHNQIITKVYNHEPLDFDVIYNESMTNYQFIKNNIIDSGYEVSNLINENKFVLFEGAQGVLLDIDHGTYPFVTSSNCSANNASIGTGIHNKQINKVLGIVKAYNTRVGSGAMVSEIKTELAHKLRERGREYGLNTGRPRRIGWLDLVALKYAIRVGGIDQLFLTLFDVLDTETKIKICTHYKLDGKIIDWFPASDYELKRCEPVYEELDGWNQDITKVTSFEELPINAQKYIKRIEEIVKVPFLGFSVGSDRKQTILIKGEFDD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S4A11_HUMAN
Sequence: MAAATRRVFHLQPCENSPTMSQNGYFEDSSYYKCDTDDTFEAREEILGDEAFDTANSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLMAMLFTDAGAPMRGKVHLLSDTIQGVTATVTGVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMDAEHRP
What is the function of this protein?
Multifunctional transporter with an impact in cell morphology and differentiation.  In the presence of borate B(OH)4(-), acts as a voltage-dependent electrogenic Na(+)-coupled B(OH)4(-) cotransporter controlling boron homeostasis (PubMed:15525507).  At early stages of stem cell differentiation, participates in synergy with ITGA5-ITGB1 and ITGAV-ITGB3 integrins and BMPR1A to promote cell adhesion and contractility that drives differentiation toward osteogenic commitment while inhibiting adipogenesis (By similarity).  In the absence of B(OH)4(-), acts as a Na(+)-coupled OH(-) or H(+) permeable channel with implications in cellular redox balance (PubMed:15525507, PubMed:28642546).  Regulates the oxidative stress response in corneal endothelium by enhancing antioxidant defenses and protecting cells from reactive oxygen species (PubMed:28642546).  In response to hypo-osmotic challenge, also acts as water permeable channel at the basolateral cell membrane of corneal endothelial cells and facilitates transendothelial fluid reabsorption in the aqueous humor (PubMed:31273259, PubMed:25007886, PubMed:23813972).  In the presence of ammonia, acts as an electrogenic NH3/H(+) cotransporter and may play a role in ammonia transport and reabsorption in renal Henle's loop epithelium (PubMed:27581649).
What are the official names of this protein?
Solute carrier family 4 member 11, Sodium borate cotransporter 1, NaBC1.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: HBAB_SERQU
Sequence: MSLSAKDKTTVKKFWDKVEGKSAEIGGEALGRMLVAYPQTKAYFSHWGSDLNPQHPMVKKHGAIIMGGIGKAVKNIDDLVRGLSALSELHAFKLRVDPANFKILAHNVILVAAMYFPADFTPEVHVSVDKFLQRVALALAERYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-B, Alpha-B-globin, Hemoglobin alpha-B chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PRP22_SCHPO
Sequence: MDDLKELEYLSLVSKVASEIRNHTGIDDNTLAEFIINLHDQSKNYDEFKNNVLSCGGEFTDSFLQNISRLIKEIKPKDDIPTDNVNNGSNSVNGASHDLDSKDVDKQHQRKMFPGLSIPNSTNNLRDRPALMDNAMDELEELSTLAKTRRNDRDSRRDERHYLNGIRERRERSISPSFSHHSRTSISGQSHSSRSSRGPLLNAPTLYGIYSGVVSGIKDFGAFVTLDGFRKRTDGLVHISNIQLNGRLDHPSEAVSYGQPVFVKVIRIDESAKRISLSMKEVNQVTGEDLNPDQVSRSTKKGSGANAIPLSAQNSEIGHVNPLETFTSNGRKRLTSPEIWELQQLAASGAISATDIPELNDGFNTNNAAEINPEDDEDVEIELREEEPGFLAGQTKVSLKLSPIKVVKAPDGSLSRAAMQGQILANDRREIRQKEAKLKSEQEMEKQDLSLSWQDTMSNPQDRKFAQDVRDSAARQLTSETPSWRQATRNANISYGKRTTLSMKEQREGLPVFKLRKQFLEAVSKNQILVLLGETGSGKTTQITQYLAEEGYTSDSKMIGCTQPRRVAAMSVAKRVAEEVGCRVGEEVGYTIRFEDKTSRMTQIKYMTDGMLQRECLVDPLLSKYSVIILDEAHERTVATDVLFGLLKGTVLKRPDLKLIVTSATLDAERFSSYFYKCPIFTIPGRSYPVEIMYTKQPEADYLDAALMTVMQIHLSEGPGDILVFLTGQEEIDTSCEILYERSKMLGDSIPELVILPVYSALPSEIQSRIFEPAPPGGRKVVIATNIAETSLTIDGIYYVVDPGFVKQSCFDPKLGMDSLIVTPISQAQARQRSGRAGRTGPGKCYRLYTESAYRNEMLPSPIPEIQRQNLSHTILMLKAMGINDLLNFDFMDPPPAQTMIAALQNLYALSALDDEGLLTPLGRKMADFPMEPQLSKVLITSVELGCSEEMLSIIAMLSVPNIWSRPREKQQEADRQRAQFANPESDHLTLLNVYTTWKMNRCSDNWCYEHYIQARGMRRAEDVRKQLIRLMDRYRHPVVSCGRKRELILRALCSGYFTNVAKRDSHEGCYKTIVENAPVYMHPSGVLFGKAAEWVIYHELIQTSKEYMHTVSTVNPKWLVEVAPTFFKFANANQVSKTKKNLKVLPLYNRFEKPDEWRISKQRKGGR
What is the function of this protein?
Acts late in the splicing of pre-mRNA.  Required for the splicing of introns with a branch nucleotide to 3'-splice site distance greater or equal to 15.  Mediates the release of the spliced mRNA from spliceosomes.
What are the official names of this protein?
Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRE_YERPG
Sequence: MKAYQREFIEFALNKQVLKFGEFTLKSGRISPYFFNAGLFNTGLDLAKLGRFYAAALMDCGVEFDLLFGPAYKGIPIATTTAVALAEHHERDVPYCFNRKEAKTHGEGGNLVGSPLQGRVMLVDDVITAGTAIRESMEIINAQGATLAGVMISLDRQERGRGEISAIQEVERDYHCKVIAIVTLNDVIRYLEDKPEMAEHLVAVRQYREQYGVTL
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RBL_NOSP7
Sequence: MSYAQTKTQSKSGYQAGVKDYRLTYYTPDYTPKDTDLLAAFRMTPQPGVPPEEAGAAVAAESSTGTWTTVWTDLLTDLDRYKGRCYDIEPVPGEDNQYICYVAYPLDLFEEGSVTNVLTSIVGNVFGFKALRALRLEDIRFPVAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINSAPFQRWRDRFLFVAEAINKAQAETGEIKGHYLNVTAPTCEQMLQRAEYAKELKQPIIMHDYLTAGFTANTTLARWCRDNGILLHIHRAMHAVIDRQKNHGIHFRVLAKALRLSGGDHIHTGTVVGKLEGERGITMGFVDLLRENYIEQDKSRGIYFTQDWASLPGVMAVASGGIHVWHMPALVEIFGDDSVLQFGGGTLGHPWGNAPGATANRVALEAVVQARNEGRNLAREGNDIIREAAKWSPELAVACELWKEIKFEFEAMDTV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: SKG1_YEAST
Sequence: MTASTSVAVGCAVGIPVGVGIIIAVCFWFNLQKRYKREEQDDRELERAIYDESGFVSFDNFGPLRDSKDEAALASSELKNPDHTSGSSEGSAHPEEKDGKSRDQEKPLGKKNSKYYVPAYRRKINLLQVRNNNYGNNARQKSVVDLPSINNSSNVSLSSSQRHITKRQISVYDQMVPVISDEGPNFFADPSSDTNTSNDQNKASMIELKHNTRQSSNENLIRNLQNQDFGSYYPRRASSSFLNGNISNASFHTRNSSITSVNKRDALEDVFATPKSAAQSQLPNTFDKDNEGMDADHSVKDSRSAITDKDKDLYKLQNNYDVGNIGEIAEEDQYENEFTNYSQSKREFIESLRPK
What is the function of this protein?
Plays a role in cell wall integrity.  Affects the cell wall polymer composition in the growing region of the cell.
What are the official names of this protein?
Suppressor of lethality of KEX2 GAS1 double null mutant protein 1.
What is the protein family that this protein belongs to?
Belongs to the SKG1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein; Cytoplasmic side. Bud membrane; Single-pass type III membrane protein; Cytoplasmic side. Note=Localizes on the inner surface of the plasma membrane at the bud and in the daughter cell. Localizes at an incipient bud site in the cells with emerging buds, a bud tip in small- or medium-budded cells, and a cell periphery in large-budded cells.
Protein: YADV_ECOLI
Sequence: MFFNTKHTTALCFVTCMAFSSSSIADIVISGTRVIYKSDQKSVNVRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTASTSLPKDRESVFWFNVLEVPPKPDAEKVANQSLLQLAFRTRIKLFYRPDGLKGNPSEAPLALKWFWSGSEGKASLRVTNPTPYYVSFSSGDLEASGKRYPIDVKMIAPFSDEVMKVNGLNGKANSAKVHFYAINDFGGAIEGNARL
What is the function of this protein?
Part of the yadCKLM-htrE-yadVN fimbrial operon.  Could contribute to adhesion to various surfaces in specific environmental niches.
What are the official names of this protein?
Probable fimbrial chaperone YadV.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.