PharMolix/UniProtQA huggingface dataset:
Protein: FIBB_FELCA
Sequence: IIDYYDEGEEDRDVGVVDAR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1017_METJA
Sequence: MKVKVYRVGGITGIFLIFLILLLLIILAIVALPIFLILMAIFGGYILLKYKIKSFFRKVWYNIRKKKIKIEDTSTNGEVKINFAKRIEIEDGKIETNNINTLLDYLDENTKSFAYYLKNIGAEFRDDGIYFKGYKIYPIFKKSYPINEIISLRYPENIDAVVLGLKGEPYDPKFLYLIPKEFLKDRMSISELKRFEIGDMVLK
What are the official names of this protein?
Uncharacterized protein MJ1017.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VU5_HHV7J
Sequence: MEIVRNGIKCCLAWPPNYVLIFGEFYHFKCRRSVITYDWSNLVGADEFLCAVGYAHPNYREPDPDFDPFVMYCSSNKMLALDTVTDELYIIAESPAHFCSIGLRNFPPFARIELDIELDRLWYGETKCSGEEFVLLQKNIPALKNFVNRQCGQKIRIDAFQNFDLSFCSSNDIHYITGSGILEKILRRKYVVIGTCARCQVEPNCRAVILLGPNFHIYVYCDNKINKVARSIREFIRRGFEELLYKERYALNWHDDSLIYVSESEAENLNRMLNGESPILRKKPRHMYPRCDRYVKIKVLLFGILYTILLLMVPWMFFFRLLKNMPSILFAVHSSEISNPLVQSVTKFLHPIIIPNGDTELKYIVPVTESRLINGLQASAAGRFGIKGLRLCSDGVIWNRLIDYEYEMFKYPSTFTRADKFLLQLRDLKFMEDFDPKWQCITKLAAVGFYSGASLFNLGAKPGIGYWCRYLCEYLSMLFFKLDGKLKELSKESKQKLGGFSCAFWSESFKTEMQNKTESFFRRDFFDRFQLYLLEHFLLFCGCEECRYNFFRFKNVGTMKKNPGSVKLHFFPALGKIDLPIFPHLSEKYSNLSMFVAKDLCLSFIEGQIEHSRFPISVTVDMGQDKRNLLNILSNIVFLLFIIQTLNSVLFTELKMYYDVYLDELKNLESSMECEMKLGSKGCMNNIVYFNMLKQVKDIVRNPGTSSNFIFNCLEVIKMSFEIPYYKNYDETNFMESFYLHHLYIQRQPAKHTDLVAANNLAPGFFIVNAKEKSFIDVLERSIVNIEAEYLSNTKNINGAMALFFSGLKYFGNFGNGNFQTSPEKDVRAVGYKLGGLDKIQNDLCYFANVETLACVGVDASDGNE
What are the official names of this protein?
Protein U5.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U4 family.
Protein: KTHY_MAGMM
Sequence: MQGRFITFEGGEGAGKSTQIAQLTQSLQAHGVKVLCTREPGGCPISERIREILVTGQGDDLDGTSELLLILAARHEHIRQVIRPALASGHWVLCDRFEDSTLAYQGGGRGGDGPWLRQLGQWIRGDVFPDLTLLLDLDPTVGLARSKRRGGQEQRFEQEALSFHQQVRQAFLQMAQQEPQRMIPIDADQPVQMVAATIWREVEGRFFVSF
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: PGK_PSEPW
Sequence: MTVLKMTDLDLQGKRVLIREDLNVPVKDGVVTSDARILAALPTIKLALEKGAAVMVCSHLGRPTEGEFSAENSLKPVADYLSKALGRDVALVADYLDGIEVKAGDLVLFENVRFNKGEKKNADELAQKYAALCDVFVMDAFGTAHRAEGSTHGVAKFAKVAAAGPLLAAELDALGKALKAPAKPMAAIVAGSKVSTKLDVLNSLSSVCDQLIVGGGIANTFLAAAGHPVGKSLYEPDLVETAKAIAAKVSVPLPVDVVVAKEFAESAEATVKAIADVAADDMILDIGPQTAANFAELLKSSKTILWNGPVGVFEFDQFGNGTKVLAKAIADSAAFSIAGGGDTLAAIDKYGVSAEISYISTGGGAFLEFVEGKVLPAVAILEERAKA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATL8_ARATH
Sequence: MSSRFSLTVVCLIALLPFVVGIRLIPARITSVGDGGGGGGNNGFSKLGPFMEAPEYRNGKECVSSSVNRENFVSSSSSSNDPSLVHIAMTLDSEYLRGSIAAVHSVLRHASCPENVFFHFIAAEFDSASPRVLSQLVRSTFPSLNFKVYIFREDTVINLISSSIRLALENPLNYARNYLGDILDRSVERVIYLDSDVITVDDITKLWNTVLTGSRVIGAPEYCHANFTQYFTSGFWSDPALPGLISGQKPCYFNTGVMVMDLVRWREGNYREKLEQWMQLQKKMRIYDLGSLPPFLLVFAGNVEAIDHRWNQHGLGGDNIRGSCRSLHPGPVSLLHWSGKGKPWVRLDEKRPCPLDHLWEPYDLYKHKIERAKDQSLLGFASLSELTDDSSFL
What is the function of this protein?
May be involved in pectin and/or xylans biosynthesis in cell walls.
What are the official names of this protein?
Probable galacturonosyltransferase-like 8, Like glycosyl transferase 9.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PAG57_SHEEP
Sequence: ISSRVSXLTIHPLRNIMDML
What are the official names of this protein?
Pregnancy-associated glycoprotein 57, ovPAG-57.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: JAL14_ARATH
Sequence: MERNLLSILMRRRLAERNRDAIELAAVQKMEVIGSTEGYTFDDGSDHDDVTKIFVGGGRQGIHYIEFEYVKNGQLESGVHLGVRYRGFTETFEINHLNNEHLESVEGYYDYGSGYIQGLQFKTNFRVSELIGYDEGTKFSLSVKGKRIIGFHGYMKERKIISLGGYFSWIHPRKMEAKGSKGGNQWDDGTNNDGVTKIHVRGGVEGIQYIKFDYVRKSGQHINGSIHGLSGSGFTQTFEIDHLNNEHLVCVEGYYDDESGVIQALQFKTNIKTSELLGYKKGKKFSLVDKRKKIVGFHGYADKNLNSLGAYFTTVSPTKSECYGSSKGIYWDDGVFDFIRTVYVSSNVMNVRYIKFHYYNRAVVVRQHGWNSIVEEDGEKEFELDYPNELITSVEGTMKSFSRSEIRISSLTFKTSKGRTSPTIGIASGTKFLLASKGCAVVGFYGRHDDRDLVAIGAYFSPLPPPTAEKLQAQGGNQGDSWDDGVFEGVRKLYVGQGKNCVAFLKVVYDSNTQVVIGEDHGNKTLFEVKEYELEYPSEYITAVDGCYNKVNGTEVEVITMLRIQTNKRTSIPVGCESNSSFVLKKEGYKIVGFHGKASNMINQLGVHVVPLTE
What are the official names of this protein?
Jacalin-related lectin 14.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: GLCI1_MOUSE
Sequence: MSTASSSSSQTPHSAPQRMRRSTAGSPPAAAGSGTGPAGSCAPAAGAGRLLQPIRATVPYQLLRGSQHSPTRPAAAATAAAALGSLSGPGGARGPSPSSPTPPPAAAPAEQAPRAKGRPRRSPESRRRSSSPERRSPGSPVCRVDRPKSQHIRTSSTIRRTSSLDTITGPYLTGQWPRDPHVHYPSCMRDKATQTPSCWAEEGAEKRSHQRSASWGSADQLKEIAKLRQQLQRSKQSSRHSKEKDRQSPLHGNHITISHTQAIGSRSVPMPLSNISVPKSSVSRVPCNVEGISPELEKVFIKENNGKEEVSKPLDIPDGRRAPLPAHYRSSSTRSIDTQTPSVQERSSSCSSHSPCVSPFCPPESQDGSPCSTEDLLYDRDKDSGSSSPLPKYASSPKPNNSYMFKREPPEGCERVKVFEEMASRQPISAPLFSCPDKNKVNFIPTGSAFCPVKLLGPLLPASDLMLKNSPNSGQSSALATLTVEQLSSRVSFTSLSDDTSTADSLEPSAQQPSQQQQLLQDLQVEEHVSTQNYVMI
What are the official names of this protein?
Glucocorticoid-induced transcript 1 protein, Glucocorticoid-induced gene 18 protein, Testhymin, Thymocyte/spermatocyte selection protein 1.
Protein: RS13_METAC
Sequence: MLYALQWRKYMVEENNNEELRHLVRIMNTDLQGAKPVQYALTGLPGVGRRTAKLIAKGAGVDPSAILGYLPEEEVAKLDTAIGKFEDIVPSWMLNRQKDLATGQDKHLLGTDILLTFREDINNLKKVRAYRGLRHERGLKVRGQRTKSTGRRGSTVGVSRKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: IFNA7_HUMAN
Sequence: MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFRFPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTNLKKGLRRKD
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-7, IFN-alpha-7, Interferon alpha-J, LeIF J, Interferon alpha-J1, IFN-alpha-J1.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: PAPOA_HUMAN
Sequence: MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVDMKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTSATKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTATQPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEESPKKTKTEEDETSEDANCLALSGHDKTEAKEQLDTETSTTQSETIQTAASLLASQKTSSTDLSDIPALPANPIPVIKNSIKLRLNR
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.  Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites.  May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.
What are the official names of this protein?
Poly(A) polymerase alpha, PAP-alpha, Polynucleotide adenylyltransferase alpha.
What is the protein family that this protein belongs to?
Belongs to the poly(A) polymerase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The 90 kDa form is nuclear while the 100 kDa and the 106 kDa forms are both nuclear and cytoplasmic.
Protein: CCMA_RUEST
Sequence: MIEVRDLGVSRGGLPVLAGVNFALSGGEALVLRGPNGIGKTTLLRTLARLQLPLAGEILGDAEDIAYAAHADGVKLTLTVAENLSFWSRVFAGGDPAVAIAAFNLDALQHRPAGGLSAGQKRRLSLARLMVTGRRLWILDEPTVSLDAASVQLFASSIRAHLASGGAAIMATHIDLGIEGRVLDLGPFKAKLPALDAEDLGGFL
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ADT1_ANOGA
Sequence: MTKKADPYGFAKDFLAGGISAAVSKTAVAPIERVKLLLQVQAASKQIAVDKQYKGIVDCFVRIPKEQGIGAFWRGNLANVIRYFPTQALNFAFKDVYKQVFLGGVDKNTQFWRYFLGNLGSGGAAGATSLCFVYPLDFARTRLGADVGRGAGEREFNGLLDCLKKTVKSDGIIGLYRGFNVSVQGIIIYRAAYFGCFDTAKGMLPDPKNTSIFVSWAIAQVVTTASGIISYPFDTVRRRMMMQSGRAKSEVMYKNTLDCWVKIGKQEGSGAFFKGAFSNVLRGTGGALVLVFYDEVKALLG
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein 1, ADP/ATP translocase 1, Adenine nucleotide translocator 1, ANT 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GSK1_MAGOR
Sequence: MSQNRPAAFNTLRMGEVIREKVQDGITGETRDLQYTQCKIVGNGSFGVVFQTKLSPSNEDAAIKRVLQDKRFKNRELQIMRIVRHPNIVQLKAFYYSNGERRDEVYLNLVQEFVPETVYRASRFFNKMKTTMPILEVKLYIYQLFRALAYIHSQGICHRDIKPQNLLLDPTTGILKLCDFGSAKILVENEPNVSYICSRYYRAPELIFGATNYTTKIDVWSTGCVMAELMLGQPLFPGESGIDQLVEIIKVLGTPTREQIRTMNPNYMEHKFPQIKPHPFNRVLRKADNNAIDLIARLLEYTPTERLGAIDAMVHPFFDDLRNPSTKLPDSRHQTGQVRDLPPLFDFNRHELSIAPQLNHQLVPPHVRPTLAAQGLDIDHFTPMRKEDMLARLD
What is the function of this protein?
Protein kinase that acts downstream of the MPS1 MAPK cascade as a highly conservative signal modulator that dictates growth, conidiation and pathogenicity (PubMed:28424497).  Phosphorylates HAT1 at 'Ser-8' to block its translocation from the nucleus to the cytoplasm where HAT1 positively regulates appressorium development and pathogenicity (PubMed:30776962).
What are the official names of this protein?
Glycogen synthase kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Mainly localizes to the cytoplasm at the conidial stage.
Protein: TO1A_HADVN
Sequence: MNTATGVIALLVLATVIGCIEAETRADLQGAFESYEGEAAEKIFRRSPTCIPSGQPCPYNENCCSKSCTYKEMKTATPVQRCD
What is the function of this protein?
Inhibits insect, but not mammalian, voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-hexatoxin-Hvn1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 08 (Shiva) family. 01 (omega toxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GTX3D_NEOGO
Sequence: DFKDWMKTAGEWLKKKGPGILKAAMAAAT
What is the function of this protein?
Has activity against some Gram-positive bacteria and S. cerevisiae.  Has a non-hemolytic activity.
What are the official names of this protein?
M-poneritoxin-Ng3d, M-PONTX-Ng3d, Poneratoxin, Ponericin-G4.
What is the protein family that this protein belongs to?
Belongs to the ponericin-G family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHM2A_CHICK
Sequence: MDLLFGRRKTPEELLRQNQRALTRAMRELDRERQKLEAQEKKIIIDIKKMAKQGQMDAVKIMAKDLVRTRRYVKKFITMRANVQAVSLKIQTLKSNNSMALAMKGVTKAMATMNRQLKLPQIQKIMMEFEKQAGIMDMKEELMNDAIDDAMGDEDDEEESDAVVSQVLDELGLNLTDELATLPPPGGSLAAGEGRAAEAAAALADADADLEERLKNLRRD
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 2a, Chromatin-modifying protein 2a, CHMP2a.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: IF1_CAMC1
Sequence: MAKDDVIEIDGNVVEALPNATFKVELDNKHIILCHIAGKMRMHYIKIMPGDRVKVELTPYSLDKGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBHH_ECOLI
Sequence: MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
What are the official names of this protein?
Putative isomerase YbhH.
What is the protein family that this protein belongs to?
Belongs to the PrpF family.
Protein: FPG_DICNV
Sequence: MPELPEVETCKKGLRPLLCQKTITAVDVRAARLREPLDAIALSQLIHCQITEITRRAKYLIININREDIAVLVHLGMSGSLRVLPQTEPIKKHDHIIITLNDGYSLRYHDPRRFGLFTVFHAQKPHRLLQHLGIEPLDDSCTGDVLHQHCQKRKIKINSLIMNQNIIVGIGNIYATEALFLSGIRPDRPAQTLSAAECASLMAQIKTLLTAAIARGGTTLRDFSAPDGHAGYFQQQLHVYGKSGQHCPKCGNILEDLKISNRGTVYCPHCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: CYBC1_XENTR
Sequence: MYMQVESRTGTLLHLKRNPSIRSWSLLVGISSVGLAAAYYSTDTWLWKLFYVAGCAFVALQNLEDWEEAIFDKKSGKAILITYSLYKKLLTLCKGGQEQVVVLLKEIRDVNVEEERVRYFGSGYVIVLRFVTGISHPLTQSAVLGARSDVEAVAKELTKFLEFDLVGSRPQAVEESNDSESDEALDTQ
What is the function of this protein?
Functions as a chaperone necessary for a stable expression of the CYBA and CYBB subunits of the cytochrome b-245 heterodimer.
What are the official names of this protein?
Cytochrome b-245 chaperone 1 homolog, Essential for reactive oxygen species protein, Eros.
What is the protein family that this protein belongs to?
Belongs to the CYBC1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NDRG3_PONAB
Sequence: MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETTHGMVHVTIRGLPKGNRPVILTYHDIGLNHKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVEGLVLINVDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANPDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIERPILGQNDNKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPSASMTRLARSRTHSTSSSLGSGESPFSRSVTSNQSDGTQESCESPDVLDRHQTMEVSC
What are the official names of this protein?
Protein NDRG3, N-myc downstream-regulated gene 3 protein.
What is the protein family that this protein belongs to?
Belongs to the NDRG family.
Protein: SRP54_SYNY3
Sequence: MFDALADRLEDAWKKLRGQDKISESNIKEALQEVRRALLAADVNLQVVKGFIKDVEQKALGADVISGVNPGQQFIKIVYDELVNLMGESNVPLAQAEQAPTVILMAGLQGTGKTTATAKLALYLRKQKRSALMVATDVYRPAAIDQLKTLGQQIDVPVFDLGSDANPVEIARQGVEKAKELGVDTVLIDTAGRLQIDPQMMAELAEIKQVVKPDDTLLVVDAMTGQEAANLTHTFHEQIGITGAILTKLDGDTRGGAALSVRQISGQPIKFVGVGEKVEALQPFYPDRLASRILNMGDVLTLVEKAQEAIDVGDVEKLQNKILEATFDFDDFIKQMRFMKNMGSLGGLLKMIPGMNKLSSGDIEKGEKELKRTEAMISSMTTEERKNPDLLAKSPSRRRRIAQGSGHSETDVSKLITNFTKMRTMMQQMGMGGMPGGMPGMGAMPGMGGGMFGGQPGPGFRGYRGGGGKPKKKKKKKGFGQL
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle protein, Fifty-four homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: GLPK_SHEHH
Sequence: MSKKYIIALDQGTTSSRAIVFDHSTNMVASCQREFSQMYPKPGWVEHDAMEIWASQSSTLIEALARADIHSEDVAAIGITNQRETTVIWDKATGKPVYNAIVWQCRRSKAICDELKTQGLEDYVKQATGLLLDPYFSGTKIKWILDNVDGVRERAEKGELLFGTIDTWLVWKLTEGQAHVTDPTNASRTMLFNIHTQEWDETLLKALNIPRSILPEVKPSSAVYGHTRIVGEGSHIAIAGMAGDQQAALFGQLCIEEGMAKNTYGTGCFLLMNTGTEAVQSQHGLLTTIAIGANGEVNYALEGSVFMGGATVQWLRDELGLIRDAQDTEYFASKVEDTHGVYLIPAFVGLGAPYWDPDARGALVGLTRGANRNHIIRAALEAIAYQSRDLLDAMAKDSRVELKQIKVDGGAVANDFLMQFQSDITNVEVQRPDLTETTAMGAAFLAGLAVGFWDSTDELKLKAGVERSFTPQITAQKRDSLYQGWQNAVARTR
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: GSHB_BRAJU
Sequence: MVGGCSSLSYSSSSTFIATTTLSSSLKLNPQSFIFHLNLRKRPPLRCLSSLTMESPKPILDFEKFDDGFVQKLVYDALVWSSLHGLVVGDKTHQRSGTVPGVGMMHAPIALLPTPFPESYWNQACEVAPIFNELVDRISLDGKFIQDSLSRTRKADVFTSRLLEIHSKMLESNKREEIRLGLHRSDYMLDEETKSLLQIEMNTISCSFPGFGRLVTELHQSLLRSHGDHLGLDSKRVPRNGSTSQFADAMAKAWLEYNNPRAVVMVVVQPDERNMYDQHWLSSVLREKHNIVTIRKSLAEVETEGRVHEDGTLTVGGQAVSVVYYRSGYTPRDYPSESEWNARLLIEQSSAVKCPSIAYHLAGTKKIQQELAKPGVLERFMDNKDDIAKLRKCFAGLWSLDDPEIIKKAIEKPELFVMKPQREGGGNNIYGDDVRENLLRLQREGEEENAAYILMQRIFPKVSNVFLLRDGVYHKDQAISELGVYGAYLRNKERVIINEHSGYLMRTKVSSSDEGGVAAGYAVLDSIYLN
What are the official names of this protein?
Glutathione synthetase, chloroplastic, GSH synthetase, GSH-S, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic GSH synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YIDC_GEOSL
Sequence: MEKRALIAVVLSILFFYGYTALFSPPPKETPKPVATATQSQPAQQVTAAPVPVAVPAQPQPAVAARDVSVDTPAYSVTFSTQGGSIKRLDLKRYHETAGPGGKNVTLVSEDNPSNYTIGLRAPGFGLDQNAVFVPSADALTVGPGEKKQLSFTWVSPAGVTVTKTYNFSGDGYGLEIQYQVTNSGSARVSSPVQTVQTYPLVPKVKESRFETFGPATFAQDKLFEDKVKDLESGAKTHAAPLWSGFADKYFLSAVLAHEGSMAAATIRKTASGYLENTISSPELSLNPGEGRALTYRLFFGPKDIDVLKAQGNSLERAINLGWFAMLAKPLLHSLKFFHNYTGNYGIAIIIITVIIKVIFYPLTHSSYKSMKEMQKLQPKMQQLREKYKNDREAMNRAMMELYQTHKVNPVGGCLPMLVQIPVFFALYKALMFSIELRHAPFMLWITDLAAKDPYYVTPIIMGVTMVIQQKMTPSQMDPVQQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQYYINRSISTAEAK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y667_RICTY
Sequence: MHKLLLIITVFSTFNVAQASLTSIVASVNDKPITFNEFHARKKMIMVLNNVENLTSDQDKQLSDLAINSLIDESLLFQYAGDREIQQDEIDNAIKSIEDRNKMPHGSLLQYLKNKSVNPESFIFQIKSELIKMNILSSLSRSVQVSNKEIDVAILSSDQKDVEILMQVFRSKDGSNKAFTKMNYLKNRLKKCSDVKKTLYDKFATMQLITSKLSKLGGVKQTIVKDLIPDKASNVFEVNNKFEIILVCSKKILNVTVDENNYVVNFLTNKKISQKAQKIFKNMRKKAAITIMFPS
What are the official names of this protein?
Uncharacterized protein RT0667.
Protein: GLGC_MYCS2
Sequence: MRELPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVNARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYTGSADAIYQSLNLIYDEDPDYIIIFGADHVYRMDPEQMMQFHIESGAGATVAGIRVPRSEASAFGCIDADESGRIREFIEKPADPPGTPDDPEQTFVSMGNYIFTTKVLIDAIRADADDDHSDHDMGGDIIPRLVADGMAAVYDFKNNEVPGATERDHGYWRDVGTLDAFYDAHMDLVSVHPVFNLYNKRWPIRGESENLAPAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVVDDGAIVEGSVLMPGVRIGRGAVVRHAILDKNVVVGPGEMVGVDLDKDRERFAISAGGVVAVGKGVWI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.