PharMolix/UniProtQA huggingface dataset:
Protein: PANE_STRPQ
Sequence: MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGLVVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLNGLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPSNQEAGHQVADLLNEANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEIIHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAVNTKGEKLGINTPYCRMITELVHAKEAVLNIQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_VIBC3
Sequence: MKIQLIAVGTKMPKWVEEGFQEYRRRFPHDMPLELVEITAGKRGKNADIARILQKEGEAMLAAVPKGNRIVTLDIPGKRWDTEELAVQLESWKLDGRDVSILIGGPEGLAPACKAAADQSWSLSPLTLPHPLVRVVMAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_PIG
Sequence: MNGTEGPNFYVPFSNKTGVVRSPFEYPQYYLAEPWQFSMLAAYMFMLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGLALTWVMALACAAPPLVGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFSIPLVIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVVAFLICWLPYASVAFYIFTHQGSDFGPIFMTIPAFFAKSASIYNPVIYIMMNKQFRNCMLTTLCCGKNPLGDDEASTTTSKTETSQVAPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Required for photoreceptor cell viability after birth (PubMed:9335046).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: HXA7_MORSA
Sequence: MSSYYVDGLLSKYTAGSSLFPNVERASCSIGPSGEDYGSARTTAAIAFAPSLSGVYSVSDAVYQSRPVFTSGYGQGQDAHTLHCSLFDQSRLFTDSCCHPEPGPLTSPPDKQYRMYPWMRASDPTRKRGRQTYSRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDHKEEPVSTPSGEKDCDIQPVSEAEEPKAVNNPERRFGVRNG
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A7.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH602_RHOP5
Sequence: MSAKEVKFGVDARDRMLRGVDILANAVKVTLGPKGRNVVLDKSFGAPRITKDGVTVAKDIELEDKFENMGAQMVREVASKSADAAGDGTTTATVLAAAIVREGAKAVAAGMNPMDLKRGIDLAVEAVVADLVKNSKKVTSNEEIAQVGTISANGDAEIGKFLSDAMKKVGNEGVITVEEAKSLETELDVVEGMQFDRGYISPYFVTNADKMRVEFDDAYILINEKKLSNLNELLPLLEAVVQTGKPLVIVAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMLQDIAILTGGQAISEDLGIKMENVTLAMLGKAKKVMIDKENTTIVNGAGKKADIEARVAQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKERKDRVDDAMHATRAAVEEGIVPGGGVALLRASEQLKGLKTKNDDQKTGVEIVRKALSWPARQIAINAGEDGSVIVGKILEKDQYNYGFDSQSGEYGNLVSKGIIDPTKVVRTAIQNAASVAALLITTEAMIAELPKKGNSGGGMPPGGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIL4_CRYNJ
Sequence: MSVMLETSLGDLIIDLEVDKCPRTCENFIKLCKLKYYALNAFFNVSKNFIAQSGDPTATGTGGESLASYVYSQSPSGPRPPRYFTPEILNSLKHTHKGTLSMAVAPINPPGCGSQFFITLADNIDYLDGKHAVFGHVIEGLDTLDKINDAFTDKEGRPLQNIRIRHVEILEDPFPDPDNFMPIPQSPIRPPDDLSKVRIADTEDPNAVIPEEEAEELRRRTEAASSALTLEMIGDLPFAAVRPPENILFVCKLNPVTQDEDLELIFSRFGKILSCEVVRDKKSGDSLQYAFIEFDEREAAEQAYFKMQNVLVDDRRIWVDFSQSVAKMNRSMLSSSNPTGRGGRGGRGGRGGNYSGRRDGDRDRDRDSGWSSRRDAPDSRRPPPPPVPMSSSRDVGGTEGYGLVFDDRSAPSSRGSKRDRERSPKRERDRERERDRSPRRDRDRERDRSPRRDRDRERDDHDRRDRDRNGRDRERNGDRERYRERSRERENERYRERDDRDRRR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 4, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ICAC_STAEQ
Sequence: MKKNKLELVYLRAFICVIIIVTHLLTQITLENEQMSDSSLILQYYIRNIFIFGTPSFIILSQLLTTLNYESVTINYLFSRFKYIFIPYLLIGLFYSYSESLITASSFKKQFIENVVLGQWYGYFIIIIMQFFVLSYIIYKINFRLFNSKILLLLAFIVQQSYLHYFLNNDTFHQFMTHYYPLSENTMILGWIFYFFLGGYIGYNYEKILSFLEKYLIIVIMLTLGAYVLFIAVSGSDYWNVTSFTYTLTLYNSVMFFLLLGVCMHFKTMLLNTIKAISAFSFFIYLLHPIILDSLFAYTNIFEDNTIVFLAISLLMILGICIGVGMMLREFYIFRFVIGKQPYKLQFDQYQPNWN
What is the function of this protein?
Presumably involved in the export of the biofilm adhesin polysaccharide poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA) across the cell membrane (By similarity).  Is essential for long-chain PIA synthesis.
What are the official names of this protein?
Probable poly-beta-1,6-N-acetyl-D-glucosamine export protein, PGA export protein, Poly-beta-1,6-GlcNAc export protein, Biofilm polysaccharide intercellular adhesin export protein, Biofilm PIA export protein, Intercellular adhesion protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARMT1_HUMAN
Sequence: MAVVPASLSGQDVGSFAYLTIKDRIPQILTKVIDTLHRHKSEFFEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPPIDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWGNKCDLSLSGGESSSQNTNVLNSLEDLKPFILLNDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMSKCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTLKAEIQVGLQPGQGEQLLASEPSWWTTGKYGIFQYDGPL
What is the function of this protein?
Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similarity).  Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism (By similarity).  Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues (PubMed:25732820).  Possibly methylates PCNA, suggesting it is involved in the DNA damage response (PubMed:25732820).
What are the official names of this protein?
Damage-control phosphatase ARMT1, Acidic residue methyltransferase 1, Protein-glutamate O-methyltransferase, Sugar phosphate phosphatase ARMT1.
What is the protein family that this protein belongs to?
Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
Protein: LGR5A_XENLA
Sequence: MDTSRTSLFLCSVLYSLQLVGSARPGKQHRSCPTPCECEQDGMLVRVDCSDRGLTGLPRNISIFTSYLDLSMNNITKLPSNALHNLHFLEELRLAGNDLTYIPKGAFAGLGSLKVLMLQNNLLRQVPSEALQNLRSLQSLRLDANHISYVPPSSFNGLFSLRHLWLDDNSLTEIPVRALESLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIYSLGKKCFDGLHSLETLDLNYNNLDEFPAAIKTLKNLKELGFHSNNIKSIPEQAFIGNPSLITTHFYDNPIQHVGRSAFQHLPELRTLILNGASQITEFPDLTGTTSLESLTLTGAQLVYLPSAVCNQLPNLKVIDLSYNHIKDLPSFSGCQRLQKIDLRHNEVYEIRFTTFQQLVGLRSLDLAWNKIAVIHPSSFSSLPSLIKLDLSSNHLTSFPVTGLHGLTHLKLTGNSALQDLIPSEHFPKLRVMEMPYAYQCCAFAVCENLKHSGQMNKDENSSADDFYRKDIGLLHLQDDRDFEDFLLDFEEDVKVLHSVQCTPSAGPFKPCDHLFGSWLTRIGVWLIVLLSFVCNALVIATVFRPLSYVPSIKLLIGLIAIINTLMGLSSGVLATVDALTFGNFAQYGAWWESGVGCQITGFLSVFAAETSVFLLTVAALERGFSIKCTTKFETKSSFLSVKLSIVFCFLLSIIIAVSPLMSGSTYGTSPFCFPLLFGDPSSMVFMVALVLLNSLCFLVMTVAYTKLYCSLEKGELENVWDCSMVKHIALLLFTNCILYCPVAFLSFSSLLNLTFISPEVNKSILLLIIPLPACLNPLLYILFNPHFKEDIGSLKNGDMLWSRSRHTSFASVSSEDAEKQSCDSTQALVTFASSSISFDLPATSSSSSYQMSNNYKLSAVAFVPCH
What is the function of this protein?
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle.  Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.  In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal.  Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development (By similarity).
What are the official names of this protein?
Leucine-rich repeat-containing G-protein coupled receptor 5A, LGR5a.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Rapidly and constitutively internalized to the trans-Golgi network at steady state.
Protein: ASTER_HUMAN
Sequence: MSTNNMSDPRRPNKVLRYKPPPSECNPALDDPTPDYMNLLGMIFSMCGLMLKLKWCAWVAVYCSFISFANSRSSEDTKQMMSSFMLSISAVVMSYLQNPQPMTPPW
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:12475939, PubMed:32814900, PubMed:36261522).  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (PubMed:32814900, PubMed:36261522).  Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein (By similarity).  Within the PAT subcomplex, WDR83OS/Asterix binds to and redirects the substrate to a location behind the SEC61 complex (By similarity).
What are the official names of this protein?
PAT complex subunit Asterix, Protein associated with the ER translocon of 10kDa, PAT-10, PAT10, WD repeat domain 83 opposite strand, WDR83 opposite strand.
What is the protein family that this protein belongs to?
Belongs to the Asterix family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MEPA_ECOHS
Sequence: MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVSTLWKPEIFSLIKLAAQDKDVTRIFVNPAIKQQLCFDAGTDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HSPQ_ECO5E
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVNDELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH1_STAAS
Sequence: MNKFKGNKVVLIGNGAVGSSYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATPYSPTTVRVKAGEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPVDILAYATWKFSGLPKERVIGSGTILDSARFRLLLSEAFDVAPRSVDAQIIGEHGDTELPVWSHANIAGQPLKTLLEQRPEGKAQIEQIFVQTRDAAYDIIQAKGATYYGVAMGLARITEAIFRNEDAVLTVSALLEGEYDEEDVYIGVPAVINRNGIRNVVEIPLNDEEQSKFAHSAKTLKDIMAEAEELK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate (Potential).  Appears to be the primary factor that allows S. aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells (By similarity).
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAE_RHIME
Sequence: MAAPVTVRVQRDDFDIAAEVSALCRARTDIGAVVTFSGLCRDEAGALSALELEHYPGMAEAEIERICHEAVERFGLQAATAIHRFGRMEPGANIVLVATASPHRQAAFDGANFIMDFLKTSAPFWKKEHHADGSAGDWVSAKDADDAARDRWTRR
What is the function of this protein?
Converts molybdopterin precursor Z into molybdopterin.  This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.  The sulfur is provided by MoaD (By similarity).
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, MPT synthase subunit 2, Molybdenum cofactor biosynthesis protein E, Molybdopterin-converting factor large subunit, Molybdopterin-converting factor subunit 2.
What is the protein family that this protein belongs to?
Belongs to the MoaE family.
Protein: CCME_PSEAB
Sequence: MNPVRKKRLIIVLAIVVGVGAAVGLALSALQQNINLFYTPTQIANGEAPTDTRIRAGGLVEKGSLQRSEDSLNVRFVVTDGAKEVTIAYHGILPDLFREGQGIVALGKLGGDGVLVADEVLAKHDENYMPPEVTKALKDSGQLKHYENGKAAGETSYNQEGK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: HOP_RAT
Sequence: MSAQTASGPTEDQVEILEYNFNKVNKHPDPTTLCLIAAEAGLTEEQTQKWFKQRLAEWRRSEGLPSECRSVTD
What is the function of this protein?
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development.  Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development.  Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF.  Overexpression causes cardiac hypertrophy.  Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding.
What are the official names of this protein?
Homeodomain-only protein, Global ischemia-induced gene 15B protein, GIIg15b, Odd homeobox protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MINE_PARPJ
Sequence: MSILSFLLGEKKKSASVAKERLQLIIAHERAGGHAPADYLPALQRELVAVISKYVKISHDDIRVSLERQDDLEVLEVKIEIPQA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: ZN330_PONAB
Sequence: MPKKKTGARKKAENRREREKQLRASRSTIDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDDHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGRQTGGEEGDGASGYDAYWKNLSSDKYGDTSYHDEEEDEYEAEDDEEEEDEGRKDSDTESSDLFTNLNLGRTYASGYAHYEEQEN
What are the official names of this protein?
Zinc finger protein 330, Nucleolar autoantigen 36.
What is the protein family that this protein belongs to?
Belongs to the NOA36 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome, centromere. Note=Predominantly expressed in nucleolus. In mitosis associated with centromeres and concentrated at the midbody in cytokinesis (By similarity).
Protein: GPDA_ERWT9
Sequence: MRSAYAAMSVIGAGSYGTALAITLARNGHEVVLWGHNPQHQAQLQADRCHQAFLPDVPFPDTLIVESDLASAITASRDVLVVVPSHVFGDVLQQIKPHLRADSRLVWATKGLEKETGRLLQDVARETLGESIPLAVISGPTFAKELAAGLPTAIALAATDGVFAEDLQQLLHCGKSFRVYNNPDFIGVQLGGAVKNVIAIGAGISDGIGFGANARTALITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGFDVEGAQDAIGQVVEGFRNTKEVKVLAERYAVEMPITEQIYQVLYCGKNTRDAALSLLGRSRKDENNGG
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PE2R3_BOVIN
Sequence: MKATRDHASAPFCTRFNHSDPGIWAAERAVEAPNNLTLPPEPSEDCGSVSVAFSMTMMITGFVGNALAITLVSKSYRRREGKRKKSFLLCIGWLALTDMVGQLLTSPVVIVLYLSHQRWEQLDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALATRAPHWYSSHMKTSVTRAVLLGVWLAVLAFALLPVLGVGQYTIQWPGTWCFISTGPGGNGTNSRQNWGNVFFASAFAILGLSALVVTFACNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNHTSVEHCKTYTENQDECNFFLIAVRLASLNQILDPWVYLLLRKILLQKFCQLLKGHSYGLDTEGGTENKDKEMKENLYISNLSRFFILLGHFTEARRGRGHIYLHTLEHQ
What is the function of this protein?
Receptor for prostaglandin E2 (PGE2) (PubMed:8396726).  The various isoforms have identical ligand binding properties but interact with different second messenger systems: isoform EP3A couples to G(i)/G(o) proteins; isoform EP3B and isoform EP3C couple to G(s), and isoform EP3D couples to G(i), G(s) and G(p) (PubMed:8396726).  Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lipopolysaccharide (LPS).  Required for normal potentiation of platelet aggregation by prostaglandin E2, and thus plays a role in the regulation of blood coagulation.  Required for increased HCO3(-) secretion in the duodenum in response to mucosal acidification, and thereby contributes to the protection of the mucosa against acid-induced ulceration.  Not required for normal kidney function, normal urine volume and osmolality (By similarity).
What are the official names of this protein?
Prostaglandin E2 receptor EP3 subtype, PGE receptor EP3 subtype, PGE2 receptor EP3 subtype, Prostanoid EP3 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VPI_CHATC
Sequence: QPNLWRCEKDEEFVNCAPRCPQNCRNIRSYQPCLVLTPVCAPGCVCRSGKVKNDRGDCVSITDCFK
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Venom peptide CtAPI, Ascaris-type protease inhibitor.
What is the protein family that this protein belongs to?
Belongs to the serine protease inhibitor-like (TIL domain-containing) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNHA2_STAS1
Sequence: MSLVYLLSTLILIMVILLFTLTNIKFQKYAGHIALLAPIVASVYFLYQLPSVMQGNFVSVKIPWLTLLDINIDFRLDGLSLFFSLLISLIGLAVVYYATQYLSKEHDNLPRFYVYLLLFMFSMLGIVTANNTILMYVFWELTSVSSFLLIVYWYSKGDSQFGAIQSFMITVFGGLALLAGFIMIYIVTGTNSITSIIEQSDKIAQSHLFIPIIILLLLGAFTKSAQFPFHIWLPKAMAAPTPVSAYLHSATMVKAGIFLLFRFTSVLGLSDFYIYSVTFVGLITMIFGAVNATRQFDMKAILAYSTISQLGMIVSMVGLGGGFAQHPTGELSKIYGMILFAALFHLMNHALYKGALFMGVGIIDHETGTRDIRRLSGLKKVFPITHIVMLLSALSMAGIPFLNGFLSKEMFFDGLVSTVELPQFNLTLTVIITVIGVIASIFTLVYGVYMIKEVFWGDYQQADLPKKSPHEPFLFTLPSAIMMILLPVIFFIPNLFGHNIILPALRSITIGEKVDQVAPHVSQWHGFNLPLILSLIVIVVGFIMALRINWKKYANQVKVKTITDLYLGSYKQFEHYSGYGIRSLMNNRLNHYITITLLIFSMVVIYGMIQAGFPEVHQIHVSDFGPIEVITLIVVFVLGIALTFIRQRLTMVVLNGIIGYCVTIFFILMKAPDLALTQLVVETITTILFIVSFSRLPNVPRAKVNKKREAVKIIVSLLMAVIVVTLVFIAQQGDSMPTISTFYHDAYKLTGGKNIVNAILGDFRAIDTLFEGMVLIIAGLGIYTLLNFKERRGQDERE
What are the official names of this protein?
Putative antiporter subunit mnhA2, Mrp complex subunit A2, Putative NADH-ubiquinone oxidoreductase subunit mnhA2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KEFG_YERPE
Sequence: MMLQPPKVLLLYAHPESQDSVANRVLLQPVQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRDHQVIVFQHPLYTYSCPALLKEWLDRVLARGFANGVGGHALTGKHWRSVITTGEQEGTYRIGGYNRYPMEDILRPFELTAAMCHMHWINPMIIYWARRQKPETLASHAQAYVQWLQSPLTRGL
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FTSB_SALEP
Sequence: MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: RS18_DICT6
Sequence: MSNEKTSTKAPKFTYSSKKKFCVFCSEKIDYIDYKNVERLKRFMTEKGKIIPRRISGNCARHQRQLSTAIKRARYMALLPYVVK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y711_CHLPN
Sequence: MFNMENTAKEEKNSQPLLDLEQDMQDHDRAQELKASVQDKVHKLHALLREGSDKESFGQQQSLLAGYVALQKVLGRINRKMI
What are the official names of this protein?
Uncharacterized protein CPn_0711/CP_0035/CPj0711/CpB0738.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0711/CT_665/TC_0036 family.