PharMolix/UniProtQA huggingface dataset:
Protein: CIN1_YEAST
Sequence: MNNIRALLDSIQSGVQTVSPEKHQQTIAAINKFQDDPALLDTILPRCVPLLTKSFFCMSQRDQKLVAELFYNLDKISHSKVLKSLDTSIFRLNEILNYLQDRASPSSFSDVLCVYLNLSWLSVILLSPYAFKDKFNKTLQVSSRFENYPICIPPINKIKAVLYFKNFTDAFDQLPEREQANVPFLNQFLKLFIQSSEKANYYFSNENLRHLQQVALSNDGIKLLPKLFQISFNHGSHDILDAIVEFFHDHLSSNSTDTRFQLAHSFAKIAKFLHQADPASFIELIDYTIENTVSLLQAPCDSIDSNELHTSLLIIAEVALAKILPIDLVDRVLTLIIPKTCHFQKSHFQIIKGHHIRDSTNFIIWSVIRSNRSNSLSPQVLQSLLSHLLINAFFDPELIIRYSSFAALQELLGRSNKSLALNQNDIALILQANWKDLPRSFEENSGLIRRLFNPENTSKSAVCVWKVFRDWSFNWNLLENLHLTTMKLNIDYNLVPLIKSKLSSPALLQEVLNKAGSSVTQNCQILYLYLKLFENDVNCPKISEICIDIYQKKIKFQLTTQAKRQFNDNSPELFQIFVILKYWQLTGQNDFNQELFWKFVDIVSPQKKLNLYNEFIPIIQQIISQCVSLNYTRIVQLIKSDNELTCRSICHMPDQEKMCSLFFSQFPLLSPQSRSLLIGELDHHWDVRISLLPSNSYRKFRNIIINCLDDYTITQQGDVGRLVRIQALKLMQSHPDFLSGDCDSINPKLTRLLAEPVPEIRKLSYQLLASATSQITVLSDSSILNFRHKQGLSEEFWKGYAVSAGAIHFTDSQLTSSIDSFIVYYRSLSPSQQLELCHDLIRIIPSAKQIAESRIRDRNKDPLTGGMRFDTIKFTIHCVKFWTRIMESGLVVLHPNFNFQGVFAKFYNLHLLDCTTLRVSVIKFFPFLAISCYHTMRENADQKNLSNIILKRLLVLVKREYAATKSKFMTDQNVALQGMFQIFLELGVTRQLQALQVACQKHELANILESDITL
What is the function of this protein?
Required for microtubule stability.  Interacts with CIN4.
What are the official names of this protein?
Chromosome instability protein 1.
Protein: KD3AB_XENLA
Sequence: MVLTQQENLSVLVGQRFVCLLGKDLQVDPDTVSKWPWKSGIVRAASHKDLHCPEIKIFVEYDDESWENRTWLELYGPTVKMFLVEHNLVLADHASPSNPSVSVQCPAMVYKVLVGKFSLGSTACLQFLGEKDKVFLSKELVKPVRDRETLKQFMQDNKTFNKAFQELIRKSVDESRLLQAARNIISMPINVYSMDPSMQWFSGTITNVRTASRALEIKCEQLPSLKIIDPALLHVVLVHNYGDQNDKSKKPRASKRKSQDTESEDQTEVKQTRNEEVPSKDVTQKTSFLTYRRDDGKTLVVVDNPKATTNNLFNYMTPATEDQQKVQQSLSSKQSVPVGFGETLLGCAATTPGIQNAATPPPANSPPSFGAATPQGKGSQNLPGDTTVLNGDANREETNLFLSAAASQGNKRSMGFGIMESPSTFSSLSTMPSWSGQPNSENGLKSENLFAAFTKSSTVFPKGFEFSVKSFPEQKMLSVTDSPKTALQKTCVPQQEQNVIRKPENNHTSVKAIKPQEPPYTKSPNKTDGVTYPKSILLNPQKLKRLQQSGDCFVQDGSCNNIAPHLHKCRECRLDRFGRSREQRDSAVFCRFFHFRRLHFNKHGMLKEGGFLTPNKYDAEAINLWLPLASSVVDLDLDTAKYILANIGDHFCKLVMSEKEVMSSTDPSKQVAWKRAVRGVREMCDACDTTIFNLHWVCPKCGFGVCVDCYRMRKKSLSSGEEGNEMFSWLKCMKGQLHEPENLMPTQIVPGKALYDVCDIVHSVRGRWGIKSNCSCSNKHMRPVSKPVVKEEVKPSTPEPEPIKSLLAQPNVCTVPDPPAIPNKPPTPACSSPLSWLTNFPQTIVNKENKDNLFASTSKSEHKPLPSFASFGKPVSALQTFGSSILTPTTSNNSGFLRNLLNASTLKQETSDKSTPKILDDIFASLVQSRPLSDFDRKPQGLPIQPSLMGFNTPHYWLCDNRLLCLQDPNNKSNWNVFRECWKQGQPVMVSGVHNNLNSELWRPESFRREFGDQEADLVNCRTNDIITGATVGDFWDGFEDIPGRLKNDTGESMVLKLKDWPPGEDFRDTMLSRFEDLMNNIPLPEYTRREGKLNLAARLPTYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGEHDQDQEVLRTIQDGDADELTIKRFIEFKEKPGALWHIYAAKDTEKIRQFLKKVAEEEGHENPPDHDPIHDQSWYLDNILRKRLLQEHGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFCLTQEFRYLSHTHTNHEDKLQVKNVIYHAVKDSIAILKANESSLGKL
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.  Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'.  Demethylation of Lys residue generates formaldehyde and succinate (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 3A-B, JmjC domain-containing histone demethylation protein 2A, Jumonji domain-containing protein 1A-B, [histone H3]-dimethyl-L-lysine(9) demethylase 3A-B.
What is the protein family that this protein belongs to?
Belongs to the JHDM2 histone demethylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CRK17_ARATH
Sequence: MAKTSCEIILCFFFFILSFRVISVSAQQTCDNTAGSFKPNSTYDNNRRLLLSTFASNVTAQNGYFNGSFGLGTDRVYAMGMCAPGAEPDVCSNCIKNTAEGLLQICLNQTDGFSWSGEETLCLVRYSNKSFSGLLGLEPSNDFFNVNEIRKEDQKEFDSVFDELMFRTIQGASSSVRNNSNSLSLSGKYYAKDVAPEPVYGNISVVMQCTPDVSSKDCNLCLERSLDFYKKWYNGKRGTIILRPSCFFRWELYTFFGAFDSINARHPPPPPRPLSPPPLKTPSVTNQTNITKKNDSRISGGTIAAIVVVVVVTIILIVVGLVICKRRKQKQEIELPIVLNEAESVQFDLKTIEAATGNFSEHNKLGAGGFGEVYKGMLLNGTEIAVKRLSKTSGQGEIEFKNEVVVVAKLQHINLVRLLGFSLQGEEKLLVYEFVPNKSLDYFLFDPNKRNQLDWTVRRNIIGGITRGILYLHQDSRLKIIHRDLKASNILLDADMNPKIADFGMARIFGVDQTVANTARVVGTFGYMSPEYVTHGQFSMKSDVYSFGVLILEIISGKKNSSFYQMDGLVNNLVTYVWKLWENKTMHELIDPFIKEDCKSDEVIRYVHIGLLCVQENPADRPTMSTIHQVLTTSSITLPVPQPPGFFFRNGPGSNPSSQGMVPGQSSSKSFTSSVDEATITQVNPR
What are the official names of this protein?
Cysteine-rich receptor-like protein kinase 17, Cysteine-rich RLK17, Protein EMBRYO DEFECTIVE 1290.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MAP21_ASPCL
Sequence: MGSKSPEGHNQAPHGAPNALDKPANPAVKAQNGSGSADLDRGTISNDDDDADDDEKETQINGSSNAGRIYLFPSRPAKFQHRPTDTPSTPEKKKKKRKRSKKKAKPTEAKQTSPPRVPLSTLFPSGYPVGELVADDRTSRVTDEETRYNSRLWDDGFLADYRQAAEIHRQVRQYAQRELIKPGATLSSIADGIEDGVRALSGHQGLETGDGLNAGMGFPTGLCVNHVAAHWTPNPGAKEVVLEKSDVLKVDFGVHVNGRIVDSAFTVAFDPVYDNLLEAVKEATNTGIAHAGIDARVSDIGAAIQEVMESYELEIAGKSVPVKAIRNITGHNILRYHIHGGKQVPFIKNNRRDKMEEGEVFAIETFGSTGKGYLDDDFGIYGYGRNEHVPATGLRLASARSLVKTIDANFGSLVFSRRYLERLGVKSYHLAMKNLIDNGIVESYAPLVDVKGSYTAQFEHTILLHSGGKEVISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2-1, MAP 2-1, MetAP 2-1, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTF8_SCHPO
Sequence: MSEIRLIRAINDELYLVEVQATLERKADSLHIGDLKIIKEKNSEKKKATLTVGNQYMEGVVESLKKPLAVLQKTNADPVDVYSSPSHELKCCSIIRERIRFSSRPLPTK
What is the function of this protein?
Essential for the fidelity of chromosome transmission.  Required for the DNA replication block checkpoint.  Replication factor C (RFC) complex has an essential but redundant activity in sister chromatid cohesion establishment.  An RFC-like complex (ctf18-RFC) is formed where ctf18 replaces rfc1 in the RFC complex along with the association of dcc1 and ctf8.  This complex is required for efficient establishment of chromosome cohesion during S-phase.  Acts as a PCNA loader, loading PCNA onto primed templates.
What are the official names of this protein?
Chromosome transmission fidelity protein 8.
What is the protein family that this protein belongs to?
Belongs to the CTF8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROB_ACAM1
Sequence: MQQTFIPVPLPQQPYQIAIASGGLTQLGSWLQDRSLQSVKLGQKVLVVSNPQIWKHYGEIVQDSLAQAGFQVEHFLLPAGERYKTPRSIQKIYDYALDLKLERSSTLVALGGGVIGDMTGFAAATWLRGINFVQVPTSLLAMVDASIGGKTGVNHPKGKNLIGAFYQPRLVLIDPDTLKTLASREFRAGMAEVIKYGVIWDLELFEVLEGCDRTNQYRYMPPHILTEILTRSAQAKADVVTQDEKEAGLRAILNYGHTIGHAIESLTGYRLFNHGEAVALGMVAAADIAVQLDWWSVEDAQRQHQLIQKTGLPTELPADFAIEAVADVLLTDKKVKDGKVRFILPTQLGKIDITDQVPGQVIVSALKGMIGQ
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTCU2_YEAST
Sequence: MFSELINFQNEGHECQCQCGSCKNNEQCQKSCSCPTGCNSDDKCPCGNKSEETKKSCCSGK
What is the function of this protein?
Protects the cell against copper toxicity by tightly chelating copper ions.  May also act as a depository for copper designated for the effective transfer into the apo forms of copper proteins.
What are the official names of this protein?
Copper metallothionein 1-2, Cu-MT, Cu-metallothionein, Copper chelatin, Copper thionein.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 12 family.
Protein: ACHD_RAT
Sequence: MAGPVPTLGLLAALVVCGSWGLNEEQRLIQHLFEEKGYNKELRPVARKEDIVDVALSLTLSNLISLKEVEETLTTNVWIDHAWIDSRLQWNANEFGNITVLRLPSDMVWLPEIVLENNNDGSFQISYACNVLVSDSGHVTWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEIRLSLKQEEEDNRSYPIEWIIIDPEGFTENGEWEIVHRAAKVNVDPSVPMDSTNHQDVTFYLIIRRKPLFYIINILVPCVLISFMINLVFYLPGDCGEKTSVAISVLLAQSVFLLLISKRLPATSMAIPLVGKFLLFGMVLVTMVVVICVIVLNIHFRTPSTHVLSEGVKKFFLETLPKLLHMSRPEEEDPGPRALIRRTSSLGYISKAEEYFSLKSRSDLMFEKQSERHGLARRLTTARKPPASSEQVQQELFNEMKPAVDGANFIVNHMRDQNSYNEEKDNWNQVARTVDRLCLFVVTPVMVVGTAWIFLQGVYNQPPPQPFPGDPFSYDEQDRRFI
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Delta/CHRND sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: ATPG_LEUCK
Sequence: MASLQDIQRRISSTKKTRQITSAMQMVSTAKLSQIQRYGRGYQAYAARLEAVVEHLVAAHLFDNADAKHIPLIAQRPIRKTGILVVTSDRGLVGSYNANVIKQTNALMARLNLDTTNTAILAVGGNGADFYKKRGFEVILEHRGVSDVPSFNEIRSVVKTVTSLYESEVFDALHVVYNHFVNRLTSEYRDVQLLPLTGDTLVAMGGTEAHKAELDIQSAYEVEPDTTAVLNVVLPQFAQSLVYEAVLDAKTAEHAASSTAMKAATDNAKDLIGRLELQFNRARQAAITTEITEITGGMAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LCE2B_HUMAN
Sequence: MSCQQNQQQCQPPPKCPPKCTPKCPPKCPPKCLPQCPAPCSPAVSSCCGPISGGCCGPSSGGCCNSGAGGCCLSHHRPRLFHRRRHQSPDCCESEPSGGSGCCHSSGGCC
What is the function of this protein?
Precursors of the cornified envelope of the stratum corneum.
What are the official names of this protein?
Late cornified envelope protein 2B, Late envelope protein 10, Skin-specific protein Xp5, Small proline-rich-like epidermal differentiation complex protein 1B.
What is the protein family that this protein belongs to?
Belongs to the LCE family.
Protein: DEOB_STAA1
Sequence: MTRPFNRVHLIVMDSVGIGEAPDAADFKDEGSHTLRHTLEGFDQTLPNLEKLGLGNIDKLPVVNAVEQPEAYYTKLSEASVGKDTMTGHWEIMGLNIMQPFKVYPNGFPEELIQQIEEMTGRKVVANKPASGTQIIDEWGEHQMKTGDLIVYTSADPVLQIAAHEDIIPLEELYDICEKVRELTKDPKYLIGRIIARPYVGEPGNFTRTSNRHDYALKPFGKTVLDHLKDGGYDVIAIGKINDIYDGEGVTEAVRTKSNMDGMDQLMKIVKKDFTGISFLNLVDFDALYGHRRDKPGYAQAIKDFDDRLPELFSNLKEDDLVIITADHGNDPTAPGTDHTREYIPVIMYSPKFKGGHALESDTTFSSIGATIADNFNVTLPEFGKSYLKELK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA12A_CONER
Sequence: MFIVFLLVVLATTVGSFTLDRVLEGRNAAAIDNALDQRDPKRQTPGCCWNPACVKNRCGRR
What is the function of this protein?
Alpha-conotoxins bind to the nicotinic acetylcholine receptors (nAChR) and inhibit them.  This peptide potently blocks muscular nicotinic acetylcholine receptor (CHRNA1-CHRNB1-CHRNG-CHRND), and has no effect on neuronal receptors.  It is able to totally displace [125I]-Bgtx from the Torpedo receptor with a complete inhibition in the high micromolar range.  It produces a biphasic inhibition curve which fits nicely with a two-site model (Ki of 0. 46 and 105 nM).
What are the official names of this protein?
Alpha-conotoxin EIIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAL_CYAP4
Sequence: MADARDMELIKPYNGDPFTGHLSTPISDSDFTRTFIGNLPAYRKGLSPILRGLEIGMAHGYFLIGPWVKLGPLRDSDVANLGGLISGIALILIATACLAAYGIVSFQKEEAAANPLNTAEGWSQFTAGFFVGATGGAFVAFTLLEKFDVVDGIMTGLFN
What are the official names of this protein?
Photosystem I reaction center subunit XI, PSI subunit V, PSI-L.
What is the protein family that this protein belongs to?
Belongs to the PsaL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SFSA_PSE14
Sequence: MRFAPQLEQGRLLIRYKRFLADIETDSGELLTIHCPNTGSMLNCMMPGGRVWFSRSSDPKRKLPGTWEISETPQGRLACINTGRANTLVEEALRAGVISELEGFTTLKREVAYGQEKSRVDFRLEYPDGYLYLEVKSVTLGFDDSSVAAFPDAVTQRGARHLRELATLAREGVRAVLLYCVNLTGIDAVRPAKEIDPVYAAALREAIDAGVQILAYGVHLTPDEIVIDRRLQVHWLD
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: EIF3C_YEAS7
Sequence: MSRFFSSNYEYDVASSSSEEDLLSSSEEDLLSSSSSESELDQESDDSFFNESESESEADVDSDDSDAKPYGPDWFKKSEFRKQGGGSNKFLKSSNYDSSDEESDEEDGKKVVKSAKEKLLDEMQDVYNKISQAENSDDWLTISNEFDLISRLLVRAQQQNWGTPNIFIKVVAQVEDAVNNTQQADLKNKAVARAYNTTKQRVKKVSRENEDSMAKFRNDPESFDKEPTADLDISANGFTISSSQGNDQAVQEDFFTRLQTIIDSRGKKTVNQQSLISTLEELLTVAEKPYEFIMAYLTLIPSRFDASANLSYQPIDQWKSSFNDISKLLSILDQTIDTYQVNEFADPIDFIEDEPKEDSDGVKRILGSIFSFVERLDDEFMKSLLNIDPHSSDYLIRLRDEQSIYNLILRTQLYFEATLKDEHDLERALTRPFVKRLDHIYYKSENLIKIMETAAWNIIPAQYKSKFTSKDQLDSADYVDNLIDGLSTILSKQNNIAVQKRAILYNIYYTALNKDFQTAKDMLLTSQVQTNINQFDSSLQILFNRVVVQLGLSAFKLCLIEECHQILNDLLSSSHLREILGQQSLHRISLNSSNNASADERARQCLPYHQHINLDLIDVVFLTCSLLIEIPRMTAFYSGIKVKRIPYSPKSIRRSLEHYDKLSFQGPPETLRDYVLFAAKSMQKGNWRDSVKYLREIKSWALLPNMETVLNSLTERVQVESLKTYFFSFKRFYSSFSVAKLAELFDLPENKVVEVLQSVIAELEIPAKLNDEKTIFVVEKGDEITKLEEAMVKLNKEYKIAKERLNPPSNRR
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 93 kDa subunit homolog, eIF3 p93, Translation initiation factor eIF3, p93 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_MESFL
Sequence: MKYTKQEARKRRHYRVRSKVSGTAAKPRLNVFKSNTNFYAQIIDDTTGTTLVSASSLNLGLKSGNIEAAKKVAEEIAKLAIAKSIVDVVFDRGGYLYHGKVKAFAEAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CYOE_PSESM
Sequence: MSLKHFIQITKPGIIFGNVLSVAGGFFLASKGNIDFGVFLAAVIGTSLVVASGCVFNNCIDRDIDQRMERTRNRVLVQGLVSLKLALLYATLLGIAGVALLYTEANPLAALFAVIGFVIYVGFYSLYLKRRSVHGTLVGSLSGAMPPVIGYCAVSNSFDFAALTLLVMFSLWQMPHSYAIAIFRFNDYRAAKIPVLPVQRGILVTKRHILLYILAFLVATLMLTVGGYAGLNYLAVAAGMGMYWLYMAWKGYKAVDDTVWARKLFVFSIFTITALSVMMSVDFQVTKELLVTYAF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSHA_MYCTU
Sequence: MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALLAVHTSPLAQPGTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPVVRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDIVHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRTVGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHPGVDLDVFRPGDRRAARAALGLPVDERVVAFVGRIQPLKAPDIVLRAAAKLPGVRIIVAGGPSGSGLASPDGLVRLADELGISARVTFLPPQSHTDLATLFRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGITGTLVSGHEVGQWADAIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDALLASYRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA
What is the function of this protein?
Catalyzes the transfer of an N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol (MSH) biosynthesis pathway (PubMed:12754249).  MSH and WhiB3 are probably part of a regulatory circuit that mediates gene expression upon acid stress (like that found in host macrophage phagosomes) (PubMed:26637353).  MSH is one of the major redox buffers which protects bacteria against redox stressors and antibiotics; loss of MSH or ergothioneine (ERG, the other major redox buffer in this bacteria) leads to respiratory alterations and bioenergetic deficiencies that negatively impact virulence (PubMed:26774486).
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: TM125_MOUSE
Sequence: MSQQASVGRGLPPDVLAEQVELWWSQQPRRSLLCFSVAVILVAGCGAGGVALLSSTSSRSGEWRLAVGTVLCLLALLVLVKQLMSSAVQDMNCIRQAQHVALLRSGGGADAVVVLLSGFVLLVTGLTLAGLAAAPAPARPLAAMLSVGITLASLGSVLLLGLLLYQVGVSGHCPPICTEAFSAQNGHGDNSSIFSISGQLSSGQRHETTSSIASLI
What are the official names of this protein?
Transmembrane protein 125.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RECF_SHESA
Sequence: MSLIRLNIDSFRNIQLAQLSPSSGINLIYGQNGSGKTSILEAIYFLGMGRSFRSHLSQRVINNEQDKLTLFATLNLPRGDSKIGLRRFRSGETEVKIDGEKVKRLSTLAETLPIQVITPESFSLLFEGPKSRRQFIDWGAFHSDPQFYAAWVNVRRVLKQRNQLLRNNSSYDQIQYWDREFVRYTEQVTEIRNRYVDSLNELLKGIIGEFLPQVDVKVSFTRGWDSKTDFAQLLESQYPRDLATGHTVSGPHKADLRLRVGSLPAQDAMSRGQLKLLVCALRIAQGKLLKQQIDKHSIYLVDDLPSELDAQHRQLLLKQLVDTGAQVFVTAIEPAAIVDSLHMPPSRMFHVEQGRVTVIE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETL_MORIN
Sequence: MSTITSYFGFLLAALTITSAIFIGLNKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RBFA_ECOUT
Sequence: MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHDEERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_EDWI9
Sequence: MKALTARQQQVYDLIRDHIEQTGMPPTRAEIAQRLGFRSPNAAEEHLKALQRKGVIEIVSGASRGIRLLMEDETGLPLVGQVAAGEPLLAQQHIEGFYQIDPSLFKPGADFLLRVNGMSMRDIGILDGDLLAVHKTQDVRNGQVVVARIEDEVTVKRLKKQGNMVQLLPENCDFQPIVVDLREQSFTIEGLAVGVIRNGDWI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: BIOH_ECO55
Sequence: MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIVLTHPERVQALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFISHPVEFCHLLVALKQRV
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYNB_NEOPA
Sequence: MKFSSANKILFSGLVASANAYDLLKDYAGDLKIGVAANAMRFSNSNYVNAMKAFNMMVAENDCKLSGIQQQKGVYNFNGCDNHYNKAKELGMEFRGHCLIWHSYQPSWFQNADANTLKNAIVDHITKTLQHYEGKIKVWDVVNEAIDDNSNGNGWNMRRSFLYNKVPNFVDLAFQTARKVSPNTKLFYNDYNAEGVYAKAESIYNFVSDLKKRNIPIDGVGLQYHVGAKEQPSYNKINDLIGRYCKLGLEVHITELDVKLQGDQNGQSQAFSNALKACLANSCCKAFLVWGVGDNDSWLGANEQALLFNGSYQPKPVYNTLLNILKTSARPASSSAKTLPGNSKSKTLPGVNSKTLPGNKSKTLPGASKTLPGNKSKTLPGGNSNTLPGNKSKTLPGGNSKTLPGNKSRTLPGGNSKTLPGGKSRTLPGGNSKTLPGGKSKTLPGGNSKTLPGGKSKTLPGGNSKTLPGGSSKTLPGGKSKTLPGGNSKTLPGGSSKTLPGGKSKTLPGGSSKTLPGGKSKTLPGGNSKTLPGGNSKTLPGGSSKTLPGGKSKTLPGGNSKTLPGGSSKTLPGGKSKTLPGGNSKTLPGGNSKTLPGGKSKTLPGGNSKTLPGGSSKTLPGGKSKTLPGGSSKTLPGGKSKTLPGGNSKTLPGGNSKTLPGGSSKTLPGGKSKTLPGGSSKTLPGGKSKTLPGGNSKTLPGGKSKTLPGGNSKTLPGGKSKTLPGGNSKTLPGGKSKTLPGGNSKTLPGGSSKTLPGGKSKTLPGGNSKTLPGGKSKTLPGGNTKTLPGGACKPTTVTVTQKVTVTVTVESQPTQGGMNQGGGNCAAKWGQCGGNGFNGPTCCQNGSRCQFVNEWYSQCL
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Hydrolyzes both unsubstituted (oat spelts) and highly substituted (rye and wheat) forms of arabinoxylanslans.
What are the official names of this protein?
Endo-1,4-beta-xylanase B, Xylanase B, 1,4-beta-D-xylan xylanohydrolase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.