PharMolix/UniProtQA huggingface dataset:
Protein: RL21_SALNS
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETIEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: COPG2_ORYSJ
Sequence: MAQPLVVKKDDDLDEEEYYSPFLGIEKGAVLQEARVFHDPQLDARRCCQVITKLLYLLNQGDTFTKVEATEVFFATTKLFQSKDAGLRRMVYLMIKELSPSADEVIIVTSSLMKDMNSKTDMYRANAIRVLCRIIDSTLLTQIERYLKQAIVDKNPVVASAALVSGIYLLQTSPEVVKRWSNEVQEAVQSRAALVQFHALALLHQIRQNDRLAVSKLVTSLTRGSVRSPLAQCLLIRYTSQVIRESSMNSQGGDRPFFDFLESCLRNKAEMVILEAARAITELNGVTSRELTPAITVLQLFLSSSKPVLRFAAVRTLNKVASTHPLAVTNCNIDMESLISDQNRSIATLAITTLLKTGNESSVDRLMKQMTNFMSDIADEFKIVVVEAIRSLCLKFPLKYRSLMNFLSNILREEGGFEYKKAIVDSIIILIRDIPDAKESGLFHLCEFIEDCEFTYMSTQILHFLGNEGPKTSDPSKYIRYIYNRVILENATVRASAVSTLAKFGALVDSLKPRIFVLLRRCLFDGDDEVRDRATLYLKLLGGEATVGETEKDVNEFLFGSFDIPLVNLETSLQNYEPSEAPFDISSVSLETKSQPLAEKKTTGKKPTGPASALSGPVPTVDASYEKLLSSIPEFAGFGKLFKSSAPVELTEAETEYSVNVVKHIYDGHVVLQYNCTNTIPEQLLEEVVVFVDASEADEFSEVATKSLRSLPYDSPGQTFVAFEKLEGVLATGKFSNILKFIVKEVDPSTGEADDDGVEDEYQLEDLEITSADYMLKVGVSNFRNAWESMDPESERVDEYGLGARESLAEAVSAVIGILGMQPCEGTDVVPSNSRSHTCLLSGVFIGNVKVLVRLSFGLSGPKEVAMKLAVRSDDPEISDKIHEIVANG
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit gamma-2, Gamma-2-coat protein, Gamma-2-COP.
What is the protein family that this protein belongs to?
Belongs to the COPG family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: BCCIP_XENTR
Sequence: MASNAKRRALEPERLPERNEEEEDDMEGDNSDESDDIEDDESEEEEEVNEEVNIDFEAYTISDTDSEGIKKLLKQLFLKAHVNISELTDLLIQQNHIGSAIKQAESQEDSDDDDDDDVDHVFGFISLVNLTERKGTSCVEQIKELILTRCEENCEQSMVEQFDKVLNNNSKPVGFLLSERFINVPAQIALPMHQQLQKELADTQRTNKPCGKCYYYLILSKTFVEAAKTSKGRVGSQAKEELMFANAEDEFFYEKALLKFSYSVQEESDTQLGGRWSFSDVPMKPLRTVMLVPADRMNSIMDKFKEYLSV
What is the function of this protein?
During interphase, required for microtubule organizing and anchoring activities.  During mitosis, required for the organization and stabilization of the spindle pole.  May promote cell cycle arrest and DNA repair.
What are the official names of this protein?
Protein BCCIP homolog.
What is the protein family that this protein belongs to?
Belongs to the BCP1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole.
Protein: MSA2_PLAFJ
Sequence: MKVIKTLSIINFFIFVTFNIKNESKYSNTFINNAYNMSIRRSMANEGSNTNSVGANAPNADTIASGSQRSTNSASTSTTNNGESQTTTPTAADTIASGSQRSTNSASTSTTNNGESQTTTPTAADTPTTTESNSPSPPITTTESSKFWQCTNKTDGKGEESEKQNELNESTEEGPKAPQEPQTAENENPAAPENKGTGQHGHMHGSRNNHPQNTSDSQKECTDGNKENCGAATSLLNNSSNIASINKFVVLISATLVLSFAIFI
What is the function of this protein?
May play a role in the merozoite attachment to the erythrocyte.
What are the official names of this protein?
Merozoite surface protein 2, Merozoite surface antigen 2, MSA-2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: CAIB_PROSL
Sequence: MTEHLPMPQFGPLAGVRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPHYPQLSRRNLHALSLNIFKDGGRDAFLKLMETTDIFIEASKGPAFARRGITDEVLWEHNPKLVIAHLSGFGQYGDPQYTNLPAYNTIAQAFSGYLIQNGDKDQPMPAFPYTADYFSGMTATTSALAALYKVQQTGKGESIDIAMYEVMLRMGQYFMMDYFNGGEICPRMTKGKEPYYAGCGLYRCQDGYIVMEVVGITQIEEIFKDIGLAHLLGTPEVPKGTQLIHRINCPHGQLFEDELDEWLANQPITAVLKRLSELNIASAKVLTIPELEGNPQYVARESITQWKTMSGETCKGPNIMPKFKNNPGKIWRGMPAHGMDTNAILKNIGYSDEQIRELVDKGLAKIVE
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity).
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_MYCVP
Sequence: MRPALTDYQHLASGKVRELYRIDGGHLLFVATDRISAYDHILKSEIPDKGRVLTAMSVFFFDYLSRTAAVSNHLAGPPDDERIPEEVLGRALVVEQLEMLPVEAVARGYLTGSGLIDYQQTGTVCGIALPSGLVEASRFDEPLFTPATKAELGEHDVNISFDDVVGLIGAERAEELRDRTLRTYSQGAAHALTRGIIVADTKFEFGVDARGELKLADEVFTPDSSRYWRADDYAEGQVQNSFDKQFVRNWLTGPDSGWDRHGDQPPPPLPPDIVDATRARYIEAYERISGLRFDDWIGVSA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: MUG61_SCHPO
Sequence: MEVPSYFDPDYDPSSLRVVDLRNILTEYQIYYPSTAKKAQLITLFSKLRRAKNGLISMTELQQKNVPPSSRSPRRRVAGVTNNVTARISSKRKINMVDEANDTEISKTSQFEDNVMGMLQDENVQVLNTNTITISEESEFHASKIAKIDSRNEEITHIPFETQTELNAAVVNLDNSMESSFSIVQNLTNKDSSVDTATYDFSAEVGNIVTPASKFLDYDQSYLVNASVSGDPTPVKVLNTTSPKSENPLNQSSFLSFLGENLKPKFTSRSSSVYASPIKSSLNSLECNPSNLLSVRKNFQQSSDSYLKSNKSFDQLNNLVGLSTGNSENFTPENNSFSWTHPKKNSSSPLPQSQSSSIFVEHLNQLYEANASIHRPVNPAFSTNFGLEASNTSTPEKKKFDSQKPDDDSVNEISSDLGLSTTGIDRVEENISLTKDRQPKRPYFSLGSFISLIFSFTKVVNSLWLVLLVVPLLGFVGFWHQEVQRVGFCGVPAEPYPSSLYYLQPGVLRSSIESAYSFAHSLGIEASCQPCPENAECGFNRQLFCKEGLKASFPLLADFGLKPYPRCIPNTVKVNKVEEMVQAFMSIIGKWYYKAPKEFATFESAKNLNGKSFVDNFKDRYYMYKQDIDNVVGLKDFKVYLKTTLNRLYNSKLTRKVLYYLFSPLFTLELWKLRVRGALSKFPTNCLRSVYSHTVSLMKYLTSAVISCWRIYLLIGILAAITGTVVWRIRVYAKKHVVKHGVSVCVSHCIAKLQKTKLKSLTDFSVNPRVEVVQLRSDCFVSGVADDKGLFELVHLPLSIQLEIWEKVVSVLEGMVSVKVWDSERLAKNRAWEWIGVFSDDIAL
What is the function of this protein?
Required for correct meiotic chromosome segregation.
What are the official names of this protein?
Meiotically up-regulated gene 61 protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Protein: BIOW_STAAB
Sequence: MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDMNNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFLESTPKQVVYETV
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.
Protein: CRR36_ARATH
Sequence: MHSSYSLSKCLVCFTILAIQTLIRRVSSLNRTNAYLNHKCLVIQGKYKRQSEYEENLNYIIDHISSTQKFPDGFTHTSRGEAPNFVTIVFQCRGDSYGSKCRSCYATPISGIRRRCQGYKGAIIWDQCFLDISTINSPPTMIDYENTFSMHNQNNVNEDAESFNKKTRDFLYNLMLKADKPKAGSYAAGEMRLGTKNLYAMVQCALDIFECKVCLEWSINELSKCCHSKKGARFLGTSCNIRYELYPFLST
What are the official names of this protein?
Putative cysteine-rich repeat secretory protein 36.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: VM1F_MACLB
Sequence: ERFAPRYIELVIVADHSVATKYNDNVTAILSWVHQLVNNIILFYRDLNVHFTLSAVEVWSNGDLINVQPEATVTLNLFGEWRERDLLNRRMHDNAQLLNNVALDDNTIGLAYDEGMCDPKYSVGIVKDHSAINRMVAATMAHEIGHNLGMNHDGSQCNCGGNGCVMSAVLMQQHSYQFSDCSKDEYQRYLTNHNPQCILNQP
What is the function of this protein?
Has fibrino(geno)lytic activity on the alpha and beta chains of fibrinogen (FGA and FGB).  Inhibits human ADP- and collagen-induced platelet aggregation on platelet-rich plasma but does not affect the thrombin-induced aggregation of rabbit washed platelets.  Slightly degrades plasminogen.
What are the official names of this protein?
Snake venom metalloproteinase fibrolase, SVMP, Fibrinolytic proteinase, Non-hemorrhagic fibrinolytic metalloproteinase, VlF.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC1_GRATL
Sequence: MTKFDHHFDYVKISLASPSKIRSWGERTLPNGQIVGEVTKPETINYRTLKPEMDGLFCERIFGPVKDWECHCGKYKRFRYKGVVCERCGVEVTESKVRRHRMAYIELAAPVTHVWYLKGTTSYIALALDLTVKDLEKIVYFHSYVVINPGNYHKLNYKQLLEGYEWRNLEEKLSSHSSNIFGIEVGIGAEAIYKLLDNINLQNTVEILREESLRPPKLFKNPSTKFNKKMKRLRLLENFLATGANPSWMVLSVIPVIPPDLRPMVQLDGGRFATADLNEFYRRIINRNNRLARLKAILAPEIIIRNEKRMLQEAVDSLMDNGRRGRTVIGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKLHQCGLPKEMALELFQPFVIHRLILQGLVNNIKAAKKIIQRNEVVVWTVLQEVIYGHPVLLNRAPTLHRLGIQAFEPILVEGRAIKLHPLVCPAFNADFDGDQMAVHVPLSLEAQAEARLLMLAPHNFLSPATGQPILMPSQDMVLGCYYLTTYNPAAISDSSHYFSNLDDALMAYQQNNITLHSLVWVRFSGLVNDSSNQMVISSKLNIDGTITKIFSDRIVKYDNDGQMVVQYIRTTAGRILFNKAIRESLL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYA_STAAN
Sequence: MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQMKVKSDDQVVEKLTQLQDEEKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_FRASN
Sequence: MIQQESRLRVADNTGAREILCIRVLGGSGRRYAGIGDIIVGTVKDALPGAGVKRGDVVKAVVVRTKKERRRPDGSYIRFDENAAVLIRDGGDPRGTRIFGPVGRELRDKRFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: EPHB4_MOUSE
Sequence: MELRALLCWASLATALEETLLNTKLETADLKWVTYPQAEGQWEELSGLDEEQHSVRTYEVCDMKRPGGQAHWLRTGWVPRRGAVHVYATIRFTMMECLSLPRASRSCKETFTVFYYESEADTATAHTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNIKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKKCSWLITNLTYFPETVPRELVVPVAGSCVANAVPTANPSPSLYCREDGQWAEQQVTGCSCAPGYEAAESNKVCRACGQGTFKPQIGDESCLPCPANSHSNNIGSPVCLCRIGYYRARSDPRSSPCTTPPSAPRSVVHHLNGSTLRLEWSAPLESGGREDLTYAVRCRECRPGGSCLPCGGDMTFDPGPRDLVEPWVAIRGLRPDVTYTFEVAALNGVSTLATGPPPFEPVNVTTDREVPPAVSDIRVTRSSPSSLILSWAIPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESESWREQLALIAGTAVVGVVLVLVVVIIAVLCLRKQSNGREVEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSVPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFEVVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQAKPGAPGGTGGPAQQF
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability.  EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells.
What are the official names of this protein?
Ephrin type-B receptor 4, Developmental kinase 2, mDK-2, Hepatoma transmembrane kinase, Tyrosine kinase MYK-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GCST_FRATM
Sequence: MLKTPLYESHIAANAKMVDFSGWSMPINYGSQIQEHNNVREDCGIFDVSHMLAVDIQGSEAEKFLRYLLANDIAKLQENKAQYGCMLNHDAGIVDDLITYKVTDEHFRIVVNAGNRESDVAWFNQNAQNFDVAITPQTDLAIVAVQGPKAVAVIKRVVTKEIAAEIEALLPFSFKFFSKWMVARTGYTGEDGFEVILPATQVKKFWDSLLENGAQPAGLGARDTLRLEAGMHLYGADMDTSTTPLERGLGWSVDLSDEHRDFIGKKAYLAKKAQGVDTKWVGVVLKTKGVLRAGQEIDFDNGEKGYITSGSFSPTLKVAIGLAYVPKQADNPVVNIRGKELEVELVKPKFVKNGKSLI
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: TNNI_ASTLP
Sequence: ADKAKAAEEAKKKQDDIDRKKAEVRKRLEEQSLKKQKKGFMTPERKKKLRLLLRKKAAEELKKEQERKAGERRKIIDQRCGQPKNLDGANEEQLRAIIKEYFDHTAQIESDKYDVELEIIRKDYEINELNIQVNDLRGKFIKPTLKKVSKYENKFAKLQKKAAEFNFRNQLKTVKKKEFELEDDKGATEGDGPAAEEVAAE
What is the function of this protein?
Troponin I is the actomyosin ATPase inhibitory subunit present in the thin filament regulatory complex.
What are the official names of this protein?
Troponin I, TnI.
What is the protein family that this protein belongs to?
Belongs to the troponin I family.
Protein: GPDA_THET8
Sequence: MRVAVLGAGAWGTALAVLLASKGVPTRLWARRKAQAEALKAMRENRDYLPGVALPAYLYPTHDPEEALEGAELAVLAVPSKALRETVAGLPPAPWYVSATKGLFYGEEGVRTPAEVVEALTQRPVVALSGPNHAEEVARFLPTASVAAGPEDLARRVQALFSGPTFRVYTSRDRRGVELGGAVKNVLALAAGMVDGLRLGDNAKAALLTRGLKEMVRFGTALGGEEATFYGLAGLGDLLATAYSLHSRNRMAGESLVRGVDREALEARGVVEGLYAVKAMVAWGKEQGVELPVAEAVHRVAHEGLDPLAALKALMAREPKEE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL39_METVS
Sequence: MAGNKPLGKKLRLAKALKQNRRVPMFAIARTKGSVKQHPKMRHWRRNTLKK
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: ANGI_COLGU
Sequence: MVMGLGLFLLVFLLGLGLTPPTLALDNPRYRDFLTKHYDATPQGRNDRYCESKMRKLGLTSPCKAINTFIHGNSRHIKAICRDENGNPYGENLRISKSPFQVTTCNLRGGSPRPPCRYRATAGFRNIVVACENDLPVHLDQSIFRP
What is the function of this protein?
Ribonuclease that cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs).  Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus.  Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA.  Angiogenin induces vascularization of normal and malignant tissues.  Angiogenic activity is regulated by interaction with RNH1 in vivo.
What are the official names of this protein?
Angiogenin, Ribonuclease 5, RNase 5.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (By similarity).
Protein: KAD_MESM1
Sequence: MIRNLIFLGAPGSGKGSTALEISTKYDIEHISTGEIFRNEIKNKTPLGLKVAEIVNDGKYVPDELTNQIVLKKLKELKQENKKFILDGYPRTLNQAMFLSSVLDEKILAVLLEVPTNLIIERLSFRRICPICKSIYHLKYNPSKKGEFCENHLENLTKIEARQDDSEESIKKRLKIYNEETKPMIDYYKKNQSLVVINSEESVKKVASLVIKKVFND
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
Protein: Y336_ACIBC
Sequence: MTKQYMTHRCLIAPPEMADDFFANTVIYLARHDEEGAQGIIINRPAGIQIKELLNDLDIDADNVNPHEVLQGGPLRPEAGFVLHTGQPTWHSSIAVGENVCITTSKDILDAIAHNEGVGRYQIALGYASWGKNQLEDEIARGDWLICDADMDLIFNLPYDDRWDAAYKKIGVDRTWLASEIGHA
What are the official names of this protein?
UPF0301 protein ACICU_00336.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: MDH_CHLTB
Sequence: MVSQTVSVAVTGGTGQIAYSFLFSLAHGDVFGLDCGIDLRIYDIPGTERALSGVRMELDDGAFPLLQRVQVTTSLHDAFDGIDAAFLIGSVPRGPGMERRDLLKKNGEIVATQGKALNTTAKRDAKIFVVGNPVNTNCWIAMNHAPRLLRKNFHAMLRLDQNRMHSMLSHRAEVPLSAVSQVVVWGNHSAKQVPDFTQALINDRPIAETIADRDWLENIMVPSVQSRGSAVIEARGKSSAASAARALAEAARSIYQPKEGEWFSSGVCSDHNPYGLPEDLIFGFPCRMLATGEYEVIPGLPWDAFIRGKMQISLDEILQEKASVSL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: RIMM_RUEST
Sequence: MSDVSEDLICVGALAGSFGVRGEVRLKSFCANAEEIEDYSPLLGADGQTRYTLAITRAIKGGFAARIVDVETKEQADALKGVQLYAPRDRLPSLPDDEFYHADLIGLEVYDTGGTLLGRVKAVQNYGADDLLELHGPGLSATVLLPFTKAAVPTVDLSQGRIIADPPAGVF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAG2L_ARATH
Sequence: MLPMEHPLPLSFVLPNPATLPGLALGFIDGNFVDLQDLLLRASTLTSNLNHDCSDLNDRLLHLRTDLTKHAVSWISTSLSAKVSLEDLRLNLESLLCLPTDSVGKQTNWELQQVVEELCRIQNRRKYFVTALKLESLVGDLEDSVFHPISKRKGSTLQDLALKQERFSHAIKTMNEIEEILGDVTRHHSRWRRLVDSVDSRVDKSLSVLRPQIIADHRAFLSSLGWPPKLATSKVEHGEVDSIPNPLLLMQGDKKESYSQSFLLLCGLQQHNTQKEKRKKLNMTKETDNDGLWATDELVKPVASRMEYHFLKWAEQPEFIFELVYKVTRDFADGVDDFLQPLIDRAMLVSCSAKEAWVSAMVQMLSGFLEKKVFPGLIDMYKEKHMKSEGISSWFHLVDQMVTFDKRMQSFVNTDTCLSYEGSSTAFSQGISVMGLFCKKPEWLKTWGKIELKDAYRKSKEDIKNEKAWVIDSERTRLGNESNSQSAKYVLSTREDYKAPLVADSFLNRTWRLIDHGLSLPAILPRIQFIRATATRFLWCIFKILLLEFKKTDLSHYGLSEDTLIQACGPVNAARYLESKLREWSDDLVFVEMWAAETSVKVDRKPEVSCQGCFFGEELKSLVELETNWLMEIITVFLHQFDNLCSDHFHNNAVSWDEDVITSSSNLTVSQGVAEALDNLRRHLCVLHLNMNPKDFLDLWRNLAEGLDHYVSRKFFSGEPVLRRQKFDRFEVDAEALLTVLKPYCVRPGAFFPRVREILRLLRMHEEEKARLRGALSRSGNTCLKLFGISNLSPQLVEQFCRSY
What is the function of this protein?
May function in the anterograde transport of protein from the endoplasmic reticulum (ER) to the Golgi complex and in the retrograde transport from the Golgi complex to the ER.
What are the official names of this protein?
RINT1-like protein MAG2L, Protein MAIGO 2 homolog, Protein MAIGO 2-like.
What is the protein family that this protein belongs to?
Belongs to the RINT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: XGPT_SALPK
Sequence: MSEKYVVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVIDIPQNTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SOTB_HELPG
Sequence: MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKRLLLFLFALFIASHILSALAWNFWVLLISRIGIAFAHSIFWSITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRIIGQMLDWRSTFGVIGGVATLIALLMWKLLPPLPSRNAGTLASVPILMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQISQFSPDITTLMLFVFGLAGVAGSFLFGRLYAKNSRKFIAFAMILVICPQLLLFVFKNLEWVIFLQIFLWGIGITSLTIALQMRVLQLAPDATDVASAIFSGSYNVGIGSGALFGSIVIHQLGLGYIGFVGGALGLLALFWLRFITIKFKKT
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TF2B_METS3
Sequence: MQGDVYDKDKQTVCPECGSTELIGDYERAEVVCAHCGLVIDENLVDMGPEWRAFDHEQRDKRTRVGAPITYTIHDKGLSTMIDWRNKDIYGRDIPARNRAQWYRLRKWQRKIRISGATERNLAFALSELDRDSSRLGLPRSVREAASVVYRSAVDNKLIRGRSIEGVVAASLYAACRRCNVPRTLDEIAEVSRVTKKEVGRTYRFLTRELNIKLPPTSPVDYVPRFASELGLSGEAQSRAIEIIEKAMEKGLTSGRGPTGVAAAALYIASVLLGERKTQRDVADIAGVTEVTIRNRYKELTEQLEMGVTL
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.