PharMolix/UniProtQA huggingface dataset:
Protein: GRC3_ASPCL
Sequence: MKRKAEKQQAAAPVSAFAARKARQQQAQVVPSEKPATNELSTEPPSKKPRRSLEEGAANLTANGEDHVQTRRSSRRKQESLRSGVSDEKQHKKAALNVRTRSAAQPPAQKDEEKDLSGALEEEDDEEVLEEENDAGAIALDGDADGYESPVDVAHLQNFPLSKTRLNKNSVIYSDEQTLCVRIKEKMNLVLLGHYDLWVKRGVVSLMGAKLHPSARVYRVYAPSTHSLPVIKCIAGVDGEAEIEVKSCHSGIYRLRHLSPLYQRIWNGKNTSADRLTLKKAPASAKRTFSVLYTSSDDSLNRHLRPLHLEKQWSSAIKSLSQRNGQLRVLICGPKASGKSTFSRYLLNHLLSPAPQTETDFRNTDGVAFLDLDPGQPEFSPMGQVYLAHLGSPFFGPPFTHPSLDGGQDGSIIRAHHIGATSPKDDPDHYVLAAMDLMDRYRSLLASYPQCPLIINYPGWIFGLGLEVATWLVKSLGLSDVVYMSEKGPAEVVEPLSQAAYEARIPLTTLPSQPTDFVSRSSAQLRSMQIQSYFHMSQPSEIQTPQWLETTISKSRPFVVDYAGPRQGIRGIMVMGSQISPDLLHDVLDGAIVGVVAVESPNAIMTGESEQPPSEPAMDEGNSQSDGDMSDVASDVAMEDGPASPSTKTAHTTPASPSFETMITRTSGEDLPYLFVGAGSCNPLDPKASNCLGLALVRSIDVPSRKLELVTPIPGLKIREALEQGHGIVLVRGMLDNPNWALSEDYYAARAAEKGHQQSVAKAKKDTGAGEDGDAAATSDQQPTVSAMLRDRIRRASNVPWMTVIEDNSRRHREAAQREKSLWKLRKKAYPGSESETDW
What is the function of this protein?
Polynucleotide 5'-kinase involved in rRNA processing.
What are the official names of this protein?
Polynucleotide 5'-hydroxyl-kinase grc3.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. NOL9/GRC3 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FA11_BOVIN
Sequence: MTLLYQMVHFALFASVAGECVTTLFQDACFKGGDITVAFAPNAKHCQIICTHHPRCLLFTFMTESSSEDPTKWYTCILKDSVTETLPMVNMTGAISGYSSKQCLHHISACSKDMYVDLNMKGMNYNSSLAQSARECQQRCTDDTHCHFFTFATRHFPSIKDRNTCLLKNTQTGTPTSITKLHEVVSGFSLKSCGLSNLACIRDIFPRTAFVDITIDTVMAPDPFVCRSICTHHPSCLFFTFLSEEWPTASERNLCLLKTSSSGLPSARFRKNRAFSGFSLQHCQHSVPVFCHSSFYRNTDFLGEELDIVDADSHEACQKTCTNSIRCQFFTYSPSQESCNGGKGKCYLKLSANGSPTKILHGTGSISGYTLRLCKMDNVCTTKIKTRIVGGTQSVHGEWPWQITLHVTSPTQRHLCGGAIIGNQWILTAAHCFNEVKSPNVLRVYSGILNQSEIKEDTSFFGVQEIIIHDQYEKAESGYDIALLKLETAMNYTDSQWPICLPSKGDRNVMYTECWVTGWGYRKLRDKIQNTLQKAKVPLMTNEECQAGYREHRITSKMVCAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCGQRERPGVYSNVVEYVDWILEKTQGP
What is the function of this protein?
Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
What are the official names of this protein?
Coagulation factor XI, FXI, Plasma thromboplastin antecedent, PTA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasma kallikrein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PROQ_ESCF3
Sequence: MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGAIRVDLDGNPCGELEEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGDKESAPRRERKPRPAAPRRKEGAERKPRAEKPAAKAPRAPREEKHTPVSDISALTVGQALKVKAGNDAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MHCKD_DICDI
Sequence: MEDNSFLKLSKKIEKILEKNDYLKKKVEQLTKSVDNHEFKIQELLLLLRKNNIHPTTTTTTTTTTNNNSTCVGISNSPPLSPRTSTDSMTNSNNSSATSSTTPSPTQTSTITTTSQIDPNSLTNSNNSFIPINSPISQTTVNNNNNNNNNNNNNNNNNNNNNNNNNNNNLNNQTITSPLSTSSSNSNSNSNSSSPIVSPVSSPQLSGSGNRPRIQFLGNGRMPSTGNLFKKEDSSDSLLKYSKDSEHLYIVPTTPRPSKSPSMDFIASTSLINTVSSNNTDSTNNDNSSILNDQQNQQQNQQQQNQQQQQEEINFITTEDKLPNLPDSNCQWAIIWEYSANDDEWTKALIIVEIDAKPFAKGALRNAYQLKIRSNAMQCFNHFATPIHEKYMEGKKLNLSQIPKLNQNLSLDTLYVAKDSKTSVNFNRYFEDVKMQMVCKSYGERYNSNHPPKKIEFLSAWVIEIQGTTNYRVGNRNSSNNTLYGLELFMKGEFKKQNSNFGTVFTERNTPQSFSHFTYECTTHEMVVVDIQGVDDIYTDPQVHTKDGKGYGEGNLGQKGIEKFLISHKCSPICLQFGLPPIGLETGRNAHRVIRGTMLLPDLTPDLYEPEYPLIENQPSNPLNSELTSIVHLSGHDERVCSLLINQDKTKLYSASADGYVKIWNLTNNEDLSKIQMIDSFRAHRRSIEKMLLNEKYLFTASSDGTIKIWSLPTTTTTTTTSKQSSSSSSSSYECIGKLEDHTAEVNDMCIDIENNFLVSCSFDKQIKIYDLSTFKCIKSLNAHGKSIKSIYMSGKYLFSSSNDQSIKIWDLEMCMCVYGMNDAHDAPITSLRMFGNRLFSASKDGEIKDWNLSTFQPTTTLDQHNMAITDILVTSNGYLFVSSDDSTIRIIDISNQNEPIKIISSTKAHRSGVNSLATDGKRIFSGGCDNLIKVWNWKNK
What is the function of this protein?
Phosphorylates threonine (By similarity).  Not critical for regulating the assembly and disassembly of myosin II filament.
What are the official names of this protein?
Myosin heavy chain kinase D, MHCK-D.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
Protein: Y917_RHIME
Sequence: MAKNVLHTIRERGFLDGQFLIAMPGMFDTNFARTVIFVCAHSEDGAMGFILNRPQRLTFPDVLLHLQLLDPDEAIRLPSATREFQIQAGGPVETGRGFVLHSDDYLSDSSIPVSDDICLTATLDIVRAISRGEGPLKATMLLGYAGWGPGQLEAEITQNGWLTCPAQEELIFSRDLDEKYDRALALMGVSPAMLSTDSGHA
What are the official names of this protein?
UPF0301 protein R00917.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: AROB_HALH5
Sequence: MSVLTVHTSSKVYNVTVKSGVLSQIGSYIAPLRPSAILIVTDDQVADLYLDTVKSSLHNLAPLHAVVLPNGEETKSFDNYYALQTAALEYGLDRKSMIIALGGGVIGDLAGFVAATYMRGIAYVQVPTTLLAHDSSVGGKVAINHPLGKNMIGAFHQPEAVLYDPQVFATLPEREWRSGFAEVVKHGLIKDAAFYAWLQKYINDFSRIQGEIAEELLLRSIQVKANIVAADEKEKGERALLNLGHTLGHAIEAELGYGKITHGEAVVIGIIFAMKLSEKVYHQSLPIQDLEKWLKFLGYETRIPKGLDTGALIGTMKKDKKVERGVIRFVLLEEVGHAVIKEVDEQLIRELLNVEIEEETT
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
Protein: RL25_BURP1
Sequence: MEKHMKVVAFERQQQGTGASRRLRNAGKTTGIVYGGEAAPQMIELDHNALWHALKKEAFHSSILDLEVAGKSQRVLLRDVQYHPFRQLVLHVDFQRIDPKKKLHTKAPLHFLNAETSPAVKLSSAVVSHVVTEIEIECLPADLPEFLEVDLSKIEAGQSLHAKDIALPNGVALTAHVDAENPVIASATIPAGAVSDEAAAGEGETPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: EX7L_LEPIN
Sequence: MEDSKPLSVSEVTRIIKNLISGSKDLKNIWVRGEISNYSKASSGHIYFSLKDAGSLIRCTFFNYSNKNYSGKPLSDGKEIQVYGTITLYEAGGSYNLNVTRVEELGQGDILLQIEKLKQKLAVEGIFDPEKKRRIPSFPKTLGIATSPTGAAIEDIIKISRSRFPGINILIAPCIVQGEDAPDSIVAAIEELNHPNWKVDVIIAGRGGGSFEDLMAFNDEKVVRAYANSRVPIISAVGHQTDVLLSDFAADHFTPTPTAAAEYAIPKEEDVLQFLSQLEGRIKSSLVTKISSNRDRLRLLSGKFIFKEPMQLLNQRSQRVDEIGIRLQKALSNKLNLARVRLERYQNLTSRIQNILFHKKQKAEFWTSKVEDLSPAATMKRGYSILRNENGKIIRSPEETKPEEELQVLLSGGTMQVIRKGK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTRB_ORYSJ
Sequence: MEGSAGAPLRTRVCIIGSGPSAHTAAIYAARAELKPVLFEGWLANDIAAGGQLTTTTDVENFPGFPEGILGGELMDRCRAQSLRFGTSIISETVTAVDFSARPFRVASDSTTVLADAVVVATGAVARRLHFAGSDAYWNRGISACAVCDGAAPIFRNKPIAVIGGGDSAMEESNFLTKYGSHVYIIHRRNTFRASKIMQARALSNPKIQVFWDSEVVEAYGGEGGGPLAGVKVKNLVTGKISDLQVSGLFFAIGHEPATKFLGGQLELDADGYVATKPGSTHTSVKGVFAAGDVQDKKYRQAITAAGSGCMAALDAEHYLQEVGAQEGKAD
What is the function of this protein?
Possesses thioredoxin-disulfide reductase activity.
What are the official names of this protein?
Thioredoxin reductase NTRB, NADPH-dependent thioredoxin reductase B, OsNTRB.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
Protein: SPDE7_HUMAN
Sequence: MEWWDKSEESLEEEPRKVLAPEPEEIWVAEMLCGLKMKLKRRRVSLVLPEHHEAFNRLLEDPVIKRFLAWDKGLRVSDKYLLAMVIVYFSRAGLPSWQYQCIHFFLALYLANDMEEDDEDPKQNIFYFLYGKTRSRIPLLRKRRFQLCRCMNPRARKNRSQIVLFQKLRFQFFCSMSCRAWVSPEELEEIQAYDPEHWVWARDRARLS
What are the official names of this protein?
Putative speedy protein E7, Speedy protein E7 pseudogene.
What is the protein family that this protein belongs to?
Belongs to the Speedy/Ringo family.
Protein: FBL52_ARATH
Sequence: MSSVSTASLNCLPDELLVHVLSSLETKQAASTSVLSKRWRTLFAVRRNLDFDDSIISHPEVGEQNMDDVQESFRDFVDKRLAFQGSVPINKFSLIYGDKHDDVRVDRWINTALEHGVSELHLCLTSVTRRLHRFPSNVFRSTTLVKLTLGTNLFIVYFPSDTCLPVLKILVLDSIWFDRIKFSNVLLAGCPALEDLTIDQKSFPGLPNVVSSKTVKSLSIVYKYSADFDWFRTVALDTPNLVTLLYSTYARHRYRHCNLESLVNATLDLHFLENCDEAFEPNVTDLMIAVRNVQMLHLTSSATEVISQCCKGGLPMFKNLLVLVFLGNTERVWKVFLPLLLEHSPNLTKLCLESLFLILQGLYHGTDEDEFDEIHIPRSNKVNMLRIIQCQGTENELKHISHFLLKMECLQLVQVNFSETIVDSKKVQLTEDLMKLPSASSRLTMQVI
What are the official names of this protein?
Putative F-box/LRR-repeat protein At3g44810.
Protein: RS8_PRUAR
Sequence: MGISRDSMHKRRATGGKKKAWRKKRKYELGRQPANTKLSSNKTVRRIRVRGGNVKWRALRLDTGNFSWGSEAVTRKTRLLDVVYNASNNELVRTQTLVKSAIVQVDAAPFKQWYLQHYGVEIGRKKKTAAAKKDTPEEGEATTEEAKKSNHVAIKLEKRQQGRTLDAHIEEQFGGGKLLACISSRPGQCGKADGDILEGKELEFYMKKLQRKKGKGAGAAA
What are the official names of this protein?
40S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: ISPE_PROMH
Sequence: MTLSWPSPAKLNLFLYITGKRPDGYHNLQTLFQFLDYGDTLTFTPRNDTQLTILTPVEGVADEDNLIIKAAKLLRQYCYQHHIPLRYQGADISIDKKLPMGGGLGGGSSNAATTLIALNYHWQAGLSDETLATLGVTLGADVPVFVKGHAAFAEGIGEILTPASPKECWYLVAHPGISIPTPTIFTDPELKRNSPIRSLGALLQAPFANDCEMIARKRFREVEYLLSWLLEYAPSRLTGTGACVFGEFESQEAASEVLINAPEWVHGFVAQGVNISPVHLFRSRIPVLLHP
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RL29_FRATO
Sequence: MKRKDTLKDYRGKSIDQLQEVKIELLQQLFSLRMQKGTGQLKKNHLFKSAKRDIARINTIISEKNK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: LIRB3_HUMAN
Sequence: MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAVKDTQSEDRVELDSQSPHDEDPQAVTYAPVKHSSPRREMASPPSSLSGEFLDTKDRQVEEDRQMDTEAAASEASQDVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSIYATLAIH
What is the function of this protein?
May act as receptor for class I MHC antigens.  Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor.  Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
What are the official names of this protein?
Leukocyte immunoglobulin-like receptor subfamily B member 3, LIR-3, Leukocyte immunoglobulin-like receptor 3, CD85 antigen-like family member A, Immunoglobulin-like transcript 5, ILT-5, Monocyte inhibitory receptor HL9.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MIAA_RICB8
Sequence: MQKKEIIILCGPTASGKSYLGHALAKACDGEIINIDSMQVYKEIPIITASPPESYKSEIPYHLYNFLPITEDFSVVKYLKLAAEKINQVTASGKLPILIGGTGLYINSLVFGYNNIPDISEDLRQQVRKLHNEIGNTELHNRLTKLDPLASSKINQSDTQRLIRAYEVVLQTGKSIFSFQTLPKEQILSEFNFKIIFLNPERKFLYKICDERLANIFKDGAIDEIALIKKQFNPDYLNLKAVGIKEILAYLENKLTLSEALNLAQTRTRRYAKRQITWFKHQIKEKITLDYSNEEDFLQVTRKLSILIDLPNSNK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: UVRB_CLAM3
Sequence: MQPTRSVRPFKVVSDYSPSGDQPTAIAELAGRVNAGEPDVVLLGATGTGKSATAAWLIEKVQRPTLILAHNKTLAAQLATEFRELMPDNAVEYFVSYYDYYQPEAYVPQTDTFIEKDSSVNAEVERLRHSTTNSLLSRRDVVVVSTVSCIYGLGQPEQYMNAMVALQVGMQIDRDTLIRKFVSMQYQRNDVDFSRGNFRVRGDTIEIIPMYEELAIRIEMFGDEIEALYQLHPLTGDVVRKMDSVSVFPGSHYVAETEVMRRAIGTIQQELEERLTVLEREGKLLEAQRLRMRTNFDIEMMQQIGFCSGIENYSRHIDGRDAGEAPHCLLDYFPDDFLVVIDESHVTVPQIGAMFEGDSSRKRTLVEHGFRLPSALDNRPLKWNEFTERVPQTVYMSATPGKYELGMGDGVVEQIIRPTGLIDPAIVVKPTKGQIDDLLEQIRIRVEKDERILVTTLTKKMAEELTDYFAEAGVRVRYLHSDVDTLRRVELLSELRAGVYDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSSTSLIQTIGRAARNVSGEVHMYADVLTDSMKRAIEETDRRREKQVAYNTEHGIDPTPLRKRIADITEILAREGEDTKKMLEGRGGGKRSPTPNLRREGKAAAGANELETIISDLNDQMLQAAGELKFELAARLRDELGDLKRELRQMEKAGHLS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYC_TUPGL
Sequence: MPLNVSFASRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVASFSPRGDDDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPSPARGHSGCSTSSLYLQDLSAAASECIDPSVVFPYPLNDGSSPKPCASPDSTAFSPSSDSLLSSTESSPRASPEPLALHEETPPTTSSDSEEDQEDEEEIDVVSVEKRQPPTKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRAKLDSGRVLKQISNNRKCASPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEKDLLRKRREQLKHKLEQLRNSCA
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.  Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.  Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.  Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).  Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: QUEA_HERAR
Sequence: MYSLSDFDFELPQELIAQTPLAERSASRLLHVAQDGMIDRAFADIVDLLNPGDLLVFNDTRVLKARFFGVKETGGKVEVLVERVIDSAHVHAQIRASKSPVPGMKIRLADAFDVIVGERAGEFYELQFPGDIFALIEAHGRLPLPPYIEHAADAYDETRYQTVYAKTPGAVAAPTAGLHFDQALLDTLKAKGVQFAYVTLHVGAGTFQPVRNENLAEHNMHSEWYTISQETVGAVHAAQAAGHNIVAVGTTSMRALESASQSGSLQAGSADTRLFITPGYTFKTVTRLITNFHLPKSTLLMLVSAFAGYDAIRAAYQHAISQRYRFFSYGDAMFLTRMPPC
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPP11_CAPGI
Sequence: MKRFFKMALFLGVSALYGQQGGMWIPSLLEGMNAKEMKTLGMKMTVADIYSVNKSSLKDAAPHFNGGCSSEVISDKGLLLTNHHCGYGQIQAHSTLQNDYLANGFWAKSLAEELPNKNLKVTFMVRIDDVTKQVLKGTESITDETEKAKLIEKNIAEVIKTAPKEAWQENSVKAFYDGNQYILFVTETFKDVRLVGAPPSSIGKFGSDTDNWVWPRHTGDFSLFRIYADKNNRPAEYSKDNVPYKPKHFFPISLKGVKEGDFVLVFGYPGTTQEYLPSAAVAQIENVINPARIGIRDIVLKVQDSYMRKDQGIKIKYAAKYARVANYWKKWMGETKGLKKSGAVALKQQQEAKFQQAIQKANKQAQYGNLLSDFNRLYKEIEPYTLAANLNSEFIFRNIDLLSNGSRLLQLEKALEDKGEQSFNDRKKNLLNTFKEIFKDNDKQVDKDVFEKVVVFYAANMPKNLLINSLKNFDAKKLADNLYNNSFLTSLSGVESVLNLSAAEFKERMKNDVGIQFVRELKEMNDTQVFPVYDRLNTQIHALQRTYMKAILEFSKPSDRIFPDANGTLRVTYGKVAGFSPADAVTYSAHTTLDGVMEKYVPGDYEFDVPQHLRDLQAKKDFGRYGDKNGKMPLCFLSTCHTTGGNSGSPAIDANGNLIGLNFDRVWEGTMSDIHYDPKLCRNIMVDIRYVLFVIDKYAGAGHLVNEMKLIK
What is the function of this protein?
Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.  Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has probably a hydrophobic residue preference at the P2 position.  Preferentially cleaves the synthetic substrate Leu-Asp-methylcoumaryl-7-amide (Leu-Asp-MCA) as compared to Leu-Glu-MCA.
What are the official names of this protein?
Asp/Glu-specific dipeptidyl-peptidase, Dipeptidyl-peptidase 11, DPP11.
What is the protein family that this protein belongs to?
Belongs to the peptidase S46 family.
Protein: RS19_STRSY
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RS10_STRPB
Sequence: MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGAKVAGPVPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: O51A7_HUMAN
Sequence: MSVLNNSEVKLFLLIGIPGLEHAHIWFSIPICLMYLLAIMGNCTILFIIKTEPSLHEPMYYFLAMLAVSDMGLSLSSLPTMLRVFLFNAMGISPNACFAQEFFIHGFTVMESSVLLIMSLDRFLAIHNPLRYSSILTSNRVAKMGLILAIRSILLVIPFPFTLRRLKYCQKNLLSHSYCLHQDTMKLACSDNKTNVIYGFFIALCTMLDLALIVLSYVLILKTILSIASLAERLKALNTCVSHICAVLTFYVPIITLAAMHHFAKHKSPLVVILIADMFLLVPPLMNPIVYCVKTRQIWEKILGKLLNVCGR
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 51A7, Olfactory receptor OR11-27.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSLV_STRM5
Sequence: MDPSQNPNVFHATTIVCVRRGEHVAIAGDGQVTLGHTVMKGNARKVRRLGRDGQVLAGFAGAAADAFTLFELFEAKLEKHGQLQRAAVELAKDWRTERRLGKLEALLAVADKETSLIISGTGDVIEPEDGIIAIGSGGSYALSAARALMAHTELDARTIASEAIGIAGDICIYTNRNVVVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNRG_FELCA
Sequence: MNLEPPKAEIRSATRVIGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII
What is the function of this protein?
Participates in processes of transmission and amplification of the visual signal.  cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones (By similarity).
What are the official names of this protein?
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma.
What is the protein family that this protein belongs to?
Belongs to the rod/cone cGMP-PDE gamma subunit family.
Protein: FGRL1_MOUSE
Sequence: MTRSPALLLLLLGALPSAEAARGPPRMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLKVKEVEAEDAGVYVCKATNGFGSLSVNYTLIIMDDISPGKESPGPGGSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDIMWMKDDQTLTHLEASEHRKKKWTLSLKNLKPEDSGKYTCRVSNKAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGSEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLISRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPMASSSSSTSLPWPVVIGIPAGAVFILGTVLLWLCQTKKKPCAPASTLPVPGHRPPGTSRERSGDKDLPSLAVGICEEHGSAMAPQHILASGSTAGPKLYPKLYTDVHTHTHTHTCTHTLSCGGQGSSTPACPLSVLNTANLQALCPEVGIWGPRQQVGRIENNGGRVS
What is the function of this protein?
Has a negative effect on cell proliferation.
What are the official names of this protein?
Fibroblast growth factor receptor-like 1, FGF receptor-like protein 1, Fibroblast growth factor receptor 5, FGFR-5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: AREH1_SCHPO
Sequence: MTDTPRILITPSPLSDISTTINKPNVHPSMSLLKALPECRLVVKSKGDKNNANVVEFPLDRHKQLLIAGKVYHDYKFKPRKSIFDRVTDPNYFAKSEFRGFYVLFWLSMAAWVLQLYARSYWQRDTLLGLPLARQVFRQFFVLFSSDFLMICLSFFSYGLQVCIEKNMIRWANLGYTIQTLWQGFYMVLAVYWVKHRDFPIVQCVFFTLHCAVLIMKQFSYSHHMGYISEIRILHNEYEKLLKFVRECLNSTEKDEKYTFELTFPNKPAETISTLQAEEIVALTAKYLSRQMRSEVGNVVYPDNINFFNYVDYLLVPSLVYSMEFPRVAHFRWHYMAFKAGSTFGLLALTLALVDWYFVPSAVAVKDLDFIGKLRIAPLLMNKIMFPAIILYLIMFYLIFDCILNAFAEITKFADRGFYGAWWNTVTWDEFSREWNKPVHVFLMRHVYHSSISGFKLKKSHAVLLTFLISALVHEFVMLLATGKFRCYILTFQLLQIPLYDLQQMFAFKKRDILGNVFFWIGMFTGPSFLCILYIVF
What is the function of this protein?
Sterol O-acyltransferase that catalyzes the formation of stery esters.
What are the official names of this protein?
Probable sterol O-acyltransferase 1, Sterol-ester synthase 1.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.