PharMolix/UniProtQA huggingface dataset:
Protein: LGT_STRS7
Sequence: MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSDDIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLFVYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMFIDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLLDGDIISFYLIWYGCGRLVIEGMRTDSLMLLGIRVSQYVSVLLIIIAIVFIFKRHRQKGISYYQE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ABRA_MOUSE
Sequence: MAPGEREREAGPAKSALRKVRTATLVINLARGWQQWANENSTKQAQEPAGWLPGATHDLPNAPKEAGPYQHAPKTLSPKPDRDGEGQHSEEATEVSHIKRKEVTRTVVSKAYERGGDVNYLSHRYENDGGVSEAIQPENDIDRILLSHDSPTRRRKCTNLVSELTKGWKVMEQEEPTWKSDSVDTEDSGYGGDMEERPEQDAAPVAPARIKRPLLSQANRYSETLNCKAHRKYSQVDNLKGRWQQWADEHVQSQKLNPFSDEFDYDLAMSTRLHKGDEGYGRPKEGSKTAERAKRAEEHIYREIMELCFVIRTMARHRRDGKIQVTFGELFDRYVRISDKVVGILMRARKHGLVHFEGEMLWQGRDDHVVITLLE
What is the function of this protein?
Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.
What are the official names of this protein?
Actin-binding Rho-activating protein, Striated muscle activator of Rho-dependent signaling, STARS.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton. Note=Localized to the I-band of the sarcomere and to a lesser extent to the sarcomeric structure between Z-lines.
Protein: NEMS_STRNA
Sequence: QDVDHVFLRF
What is the function of this protein?
Myoinhibiting neuropeptide.
What are the official names of this protein?
Myosuppressin, MS.
What is the protein family that this protein belongs to?
Belongs to the myosuppressin family.
What are the subcellular locations of this protein?
Secreted.
Protein: XYNC_EMENI
Sequence: MVHLKTLAGSAVFASLATAAVLPRQSASLNDLFVAAGKSYFGTCSDQALLQNSQNEAIVASQFGVITPENSMKWDALEPSQGNFGWSGADYLVDYATQHNKKVRGHTLVWHSQLPSWVSSIGDANTLRSVMTNHINEVVGRYKGKIMHWDVVNEIFNEDGTFRNSVFYNLLGEDFVRIAFETARAADPDAKLYINDYNLDSASYAKTQAMASYVKKWLAEGVPIDGIGSQAHYSSSHWSSTEAAGALSSLANTGVSEVAITELDIAGAASSDYLNLLNACLNEQKCVGITVWGVSDKDSWRASDSPLLFDGNYQPKDAYNAIVNALS
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase C, Xylanase C, 1,4-beta-D-xylan xylanohydrolase C, 34 kDa xylanase, Xylanase X34.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: KTHY_XANOM
Sequence: MTIELKPGGLLIAIEGIDGAGKTTLARRLTTTLEAAGARVVLSKEPTNGPWGTKLRQSAATGRLSADEEAELLIRDRHEHVDTLIAPALARGDIVILDRYFPSMVAYQGAAGLPLDELLELNAFAPRPDVLLLLDLPPPTGLARIRARGDAPNHFETQDNLERCRTIFAGLELPGKHVVDASADADSVLRQAHAIIVAALADRLSGDGAPADTGKAALELLSAGRPA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ENO_RHOE4
Sequence: MASIEQVGAREILDSRGNPTVEVEVLLEDGSFARAAVPSGASTGEHEAVELRDGGARYGGKGVEKAVEAVLGEIAPAIIGIDATEQRTVDQALLDADGTPDKSRLGANALLGASLAVARAAAESSGLELFRYVGGPNAHVLPVPMMNILNGGAHADTGVDVQEFMVAPIGAPSFKESLRWGAEVYHSLKSVLKEKGLSTGLGDEGGFAPDVAGTKEALDLITIAVNKTGLKLGTDVALALDVAATEFYTDGTGYKFEGKNRTAAEMAAFYAELIDAYPLVSIEDPLDEDDWDGWVALTDQIGNKVQLVGDDLFVTNPERLEEGIVKGAANALLVKVNQIGTLTETLDAVDLAHRNGYKTMMSHRSGETEDTTIADLAVAVGSGQIKTGAPARSERVAKYNQLLRIEENLGDAARYAGEVAFPRFAFEA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RRF_ACTP2
Sequence: MINEIKKDTQDRMEKSLEALKSHISKIRTGRAQPSLLDGIQVEYYGSATPLRQLANVVAEDARTLAVNVFDRSLISAVEKAILTSDLGLNPSSAGATIRVPLPPLTEERRRDLIKIVKGEGEQGKIAIRNVRRDANDQIKALLKDKEISEDEERKAQDEIQKITDGYVKKVDEVLAAKEKELLDF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPTS_STAA3
Sequence: MTAYKPYRHQLRRSLFASTIFPVFLVIIIGLVSFYAIYIWIEHRTIHQHVDESQSSLHHTEKQIQTFITQHNNSFQELDLTNHHDVTATKRELLKLIHQQPATLYYELSGPNQFITNNYEHLNTKNMYLFSTHQLKFKNSTYMLKIYMANTPRLSEIKKDNRQFALIVDQYDNILYANDDRFTIGEKYRPQQFGFMNESVKLNHADHRLIIYKDIHENIEDGITLLIVMAVVLVLLVIFGFISADNMAKRQTKDIETIIQKIYYAKNRHLGTYTPLKNNSELEEINNYIYDLFESNEQLIHSIEHTERRLRDIQLKEIERQFQPHFLFNTMQTIQYLITLSPKLAQTVVQQLSQMLRYSLRTNSHTVELNEELNYIEQYVAIQNIRFDDMIKLHIESSEEARHQTIGKMMLQPLIENAIKHGRDTESLDITIRLTLARQNLHVLVCDNGIGMSSSRLQYVRQSLNNDVFDTKHLGLNHLHNKAMIQYGSHARLHIFSKRNQGTLICYKIPLSRGNVDV
What is the function of this protein?
Member of the two-component regulatory system HptS/HptR that regulates genes involved in hexose phosphate transport system in response to changes in extracellular phosphate sources.  May act as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to the conserved aspartic acid residue in the regulatory domain of HptS.  In turn, HptS antagonizes CcpA-dependent transcription of a subset of CcpA-regulated genes involved in antibiotic susceptibility.
What are the official names of this protein?
Sensor protein kinase HptS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COX2_PRAJA
Sequence: MAYSFQLGLQDATSPIMEELMNFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAVILIMIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLVSSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKHFENWSASMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DPOL_PYRSD
Sequence: MILDADYITEDGKPIIRIFKKENGEFKVEYDRNFRPYIYALLKDDSQIDEVRKITAERHGKIVRIIDAEKVRKKFLGRPIEVWRLYFEHPQDVPAIRDKIREHSAVIDIFEYDIPFAKRYLIDKGLIPMEGDEELKLLAFDIETLYHEGEEFAKGPIIMISYADEEEAKVITWKKIDLPYVEVVSSEREMIKRFLKVIREKDPDVIITYNGDSFDLPYLVKRAEKLGIKLPLGRDGSEPKMQRLGDMTAVEIKGRIHFDLYHVIRRTINLPTYTLEAVYEAIFGKPKEKVYAHEIAEAWETGKGLERVAKYSMEDAKVTYELGREFFPMEAQLSRLVGQPLWDVSRSSTGNLVEWYLLRKAYERNELAPNKPDEREYERRLRESYAGGYVKEPEKGLWEGLVSLDFRSLYPSIIITHNVSPDTLNREGCREYDVAPEVGHKFCKDFPGFIPSLLKRLLDERQEIKRKMKASKDPIEKKMLDYRQRAIKILANSILPEEWVPLIKNGKVKIFRIGDFVDGLMKANQGKVKKTGDTEVLEVAGIHAFSFDRKSKKARVMAVKAVIRHRYSGNVYRIVLNSGRKITITEGHSLFVYRNGDLVEATGEDVKIGDLLAVPRSVNLPEKRERLNIVELLLNLSPEETEDIILTIPVKGRKNFFKGMLRTLRWIFGEEKRVRTASRYLRHLENLGYIRLRKIGYDIIDKEGLEKYRTLYEKLVDVVRYNGNKREYLVEFNAVRDVISLMPEEELKEWRIGTRNGFRMGTFVDIDEDFAKLLGYYVSEGSARKWKNQTGGWSYTVRLYNENDEVLDDMEHLAKKFFGKVKRGKNYVEIPKKMAYIIFESLCGTLAENKRVPEVIFTSSKGVRWAFLEGYFIGDGDVHPSKRVRLSTKSELLVNGLVLLLNSLGVSAIKLGYDSGVYRVYVNEELKFTEYRKKKNVYHSHIVPKDILKETFGKVFQKNISYKKFRELVENGKLDREKAKRIEWLLNGDIVLDRVVEIKREYYDGYVYDLSVDEDENFLAGFGFLYAHNSYYGYYGYAKARWYCKECAESVTAWGREYIEFVRKELEEKFGFKVLYIDTDGLYATIPGAKPEEIKKKALEFVDYINAKLPGLLELEYEGFYVRGFFVTKKKYALIDEEGKIITRGLEIVRRDWSEIAKETQAKVLEAILKHGNVEEAVKIVKEVTEKLSKYEIPPEKLVIYEQITRPLHEYKAIGPHVAVAKRLAARGVKVRPGMVIGYIVLRGDGPISKRAILAEEFDLRKHKYDAEYYIENQVLPAVLRILEAFGYRKEDLRWQKTKQTGLTAWLNIKKK
What is the function of this protein?
Intein encoded endonucleases are thought to mediate intein mobility by site-specific recombination initiated by endonuclease cleavage at the 'homing site' in gene that lack the intein (Probable).  Intein splicing has been shown to occur via a branched intermediate that is resolved as the reaction proceeds; formation of the branched intermediate is reversible in response to pH shifts (PubMed:8269515).
What are the official names of this protein?
DNA polymerase, Deep vent DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: POL_HTL1C
Sequence: MGQIFSRSASPIPRPPRGLAAHHWLNFLQAAYRLEPGPSSYDFHQLKKFLKIALETPVWICPINYSLLASLLPKGYPGRVNEILHILIQTQAQIPSRPAPPPPSSSTHDPPDSDPQIPPPYVEPTAPQVLPVMHPHGAPPNHRPWQMKDLQAIKQEVSQAAPGSPQFMQTIRLAVQQFDPTAKDLQDLLQYLCSSLVASLHHQQLDSLISEAETRGITGYNPLAGPLRVQANNPQQQGLRREYQQLWLAAFAALPGSAKDPSWASILQGLEEPYHAFVERLNIALDNGLPEGTPKDPILRSLAYSNANKECQKLLQARGHTNSPLGDMLRACQAWTPKDKTKVLVVQPKKPPPNQPCFRCGKAGHWSRDCTQPRPPPGPCPLCQDPTHWKRDCPRLKPTIPEPEPEEDALLLDLPADIPHPKNLHRGGGLTSPPTLQQVLPNQDPTSILPVIPLDPARRPVIKAQIDTQTSHPKTIEALLDTGADMTVLPIALFSSNTPLKNTSVLGAGGQTQDHFKLTSLPVLIRLPFRTTPIVLTSCLVDTKNNWAIIGRDALQQCQGVLYLPEAKRPPVILPIQAPAVLGLEHLPRPPEISQFPLNPERLQALQHLVRKALEAGHIEPYTGPGNNPVFPVKKANGTWRFIHDLRATNSLTIDLSSSSPGPPDLSSLPTTLAHLQTIDLKDAFFQIPLPKQFQPYFAFTVPQQCNYGPGTRYAWRVLPQGFKNSPTLFEMQLAHILQPIRQAFPQCTILQYMDDILLASPSHADLQLLSEATMASLISHGLPVSENKTQQTPGTIKFLGQIISPNHLTYDAVPKVPIRSRWALPELQALLGEIQWVSKGTPTLRQPLHSLYCALQRHTDPRDQIYLNPSQVQSLVQLRQALSQNCRSRLVQTLPLLGAIMLTLTGTTTVVFQSKQQWPLVWLHAPLPHTSQCPWGQLLASAVLLLDKYTLQSYGLLCQTIHHNISTQTFNQFIQTSDHPSVPILLHHSHRFKNLGAQTGELWNTFLKTTAPLAPVKALMPVFTLSPVIINTAPCLFSDGSTSQAAYILWDKHILSQRSFPLPPPHKSAQRAELLGLLHGLSSARSWRCLNIFLDSKYLYHYLRTLALGTFQGRSSQAPFQALLPRLLSRKVVYLHHVRSHTNLPDPISRLNALTDALLITPVLQLSPADLHSFTHCGQTALTLQGATTTEASNILRSCHACRKNNPQHQMPQGHIRRGLLPNHIWQGDITHFKYKNTLYRLHVWVDTFSGAISATQKRKETSSEAISSLLQAIAYLGKPSYINTDNGPAYISQDFLNMCTSLAIRHTTHVPYNPTSSGLVERSNGILKTLLYKYFTDKPDLPMDNALSIALWTINHLNVLTNCHKTRWQLHHSPRLQPIPETHSLSNKQTHWYYFKLPGLNSRQWKGPQEALQEAAGAALIPVSASSAQWIPWRLLKRAACPRPVGGPADPKEKDHQHHG
What is the function of this protein?
Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions.
What are the official names of this protein?
Gag-Pro-Pol polyprotein, Pr160Gag-Pro-Pol.
What are the subcellular locations of this protein?
[Matrix protein p19]: Virion. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p15-pro]: Virion.
Protein: HOME3_MOUSE
Sequence: MSTAREQPIFSTRAHVFQIDPTTKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQQLTQFAEKFQEVKEAARLAREKSQDGGEFTSTGLALASHQVPPSPLVSTNGPGEEKLFRSQSADTPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNQRLAGALREANAAATQWRQQLEVQRAEAELLRQRVAELEAQVAVEPVRAGEKEATSQSVEQLEARVQTKDQTLKNQSTGTREAPDTAEREETQQQVQDLETRNAELEQQLRSMECNLEEARAERERARAEVGRAAQLLDVRLFELSELREGLARLAEAAP
What is the function of this protein?
Postsynaptic density scaffolding protein.  Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3.  By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release.  Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (By similarity).  Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway.  Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA (PubMed:18218901).
What are the official names of this protein?
Homer protein homolog 3, Homer-3.
What is the protein family that this protein belongs to?
Belongs to the Homer family.
What are the subcellular locations of this protein?
Cytoplasm. Postsynaptic density. Synapse. Note=Postsynaptic density of neuronal cells.
Protein: ARP9_ARATH
Sequence: MAKPKSNSHLSWQDYLKTVAPTQILSERGANLVVINLGSANVRVGLAMDEKPFNVPNCIARYITQSGKPTVVDQMLNTEVTTNQHVDRERAYNSAASLLKILFLDESSSSGSASRKMGRIDGYNQASTIKKDSVFTWTDVYEDEKISLASPAETSPDKGDASASEAVPDVTDSKDTSESKRKYRKMIFGEEALKISPKEPYCLYHPIRRGHFNVSPHYSAQRVCEDLTAILDWILLEKLHITHKERFSFHAVIVVPETFDTREIKEMLTIVLGELYFNSAVVHQEGLSAVFGNGLTTACIVNIGAQTSTVVCVEDGVSLPNTEKILPFGGEDICRCLLWIQRHYQKWPQINTDVLAKPIDMLMLNQLKESFCEIRAGELETVATVHSYEEGMPAVPHKTNLTSLNVPPMGLFYPNLLVPEIFPQPPRQWFQDYENMLEDTWNMDFGGGGNMGLPMWDSFAFSPSKPKKEEKIGLAEAITSSILSAGRIDLRRKLFSSIQLIGGAGLTKGLVAAVEERVLHAIPPTEAIDTVQVLPSRTEPQFVTWKGGAILGILDFGREAWIERHQWMVNGVNKGGLKKYKDSYHLQGQAMYFINP
What are the official names of this protein?
Actin-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP8 subfamily.
Protein: PA_I70A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPIRLPDGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYIVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDNCRDISDLKQYDSDEPELRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEYIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQMSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: FOSL2_RAT
Sequence: MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPTSGLQSLRGTGSAVGPVVVKQEPPEEDSPSSSAGMDKTQRSVIKPISIAGGGFYGEEPLHTPIVVTSTPAITPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL
What is the function of this protein?
Controls osteoclast survival and size (By similarity).  As a dimer with JUN, activates LIF transcription (By similarity).  Activates CEBPB transcription in PGE2-activated osteoblasts (PubMed:15299028).
What are the official names of this protein?
Fos-related antigen 2, FRA-2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Fos subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMG_BRUC2
Sequence: MSSAEALAFDVIVIGGGHAGCEAASAAARAGARTALVTHRFDTIGVMSCNPAIGGLGKGHLVREIDALDGLMGRVADRAGIQFRLLNRRKGPAVRGPRTQADRKLYRLAMQQMITEQENLTVVEGGAADLVCDGERISGVTLADGRVLKCGAVVLTTGTFLNGLIHIGEKRFPAGRMGEKPALGLSERLLSFGFTLGRLKTGTPPRLDGRTIDWQSLDMQSADEEPVPFSLMTDRITTPQIECGITRTTPETHDIIRANLHRSAMYSGSIEGIGPRYCPSVEDKIVKFGDRDGHQIFLEPEGLDDDTVYPNGISTSLPEDVQLEILKTIPGLEKAVLLQPGYAIEYDFIDPRELKRSLETRKVCGLFLAGQINGTTGYEEAGAQGLLAGLNAARRAAGSEPVILQRTEAYIGVMVDDLTSRGVSEPYRMFTSRAEFRLSLRADNADQRLTPLADEVGILSKERRKRYLTRETALSHARMVTQSLSITPNLAGYYDLRLNQDGVRRSAYDLLSYPDINLDRLIAIWPELASIDPVTREALEIEAQYAVYMERQQSDIAVMEREERLLIPSGLDFDAISGLSNELKQKLKQRKPETIAEAQRVDGMTPAAVALLIAQIRKFGGRQKLAAETLEGKGAA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYTA_BOVIN
Sequence: MIPGGLTEAKPATIEIQEIANMVKPQLEEKTNETYEEFTAIEYKSQVVAGINYYIKIQTGDNRYIHIKVFKSLPQQSHSLILTGYQVDKTKDDELAGF
What is the function of this protein?
This is an intracellular thiol proteinase inhibitor.
What are the official names of this protein?
Cystatin-A, Cystatin-AS, Stefin-A.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y896_PSEPW
Sequence: MLTVISPAKTLDYDTPPVTERFTLPQYLDDSQELIVQLRELSPAQISELMHLSDKLAGLNAARFGSWTPDFTPANAKQALLAFKGDVYTGLDAETLSEDDFTYAQQHLRMLSGLYGLLRPLDLMQPYRLEMGTKLANARGKDLYAFWGTRISQWLNQALTEQGDDLLLNLASNEYFSAVKRSALKGRVINVDFKDLKNGQYKIISFYAKKARGMMSRFVIQERVNDPQQLKQFDVQGYYYSAEQSKPDHLVFLRDHPAE
What are the official names of this protein?
UPF0246 protein PputW619_0896.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: DTX18_ARATH
Sequence: MADPTSKDDHDGEGGRDKSSTFVQKLIDVEEAKTQIIYSLPMIFTNLFYYCIPLTSVMFASQLGQLELAGATLANSWATVTGFAFMTGLSGALETLCGQGFGAKSYRMLGIHLQSSCIVSLVFTILITILWFFTESVFLLLRQDPSISKQAALYMKYLAPGLLAYGFLQNILRFCQTQCIVTPLVLFSFLPLVINIGTTYALVHLAGLGFIGAPIATSISLWIAFVSLGFYVICSDKFKETWTGFSMESFHHVVLNLTLSIPSAAMVCLEYWAFEILVFLAGLMRNPEITTSLVAICVNTESISYMLTCGLSAATSTRVSNELGAGNVKGAKKATSVSVKLSLVLALGVVIAILVGHDAWVGLFSNSHVIKEGFASLRFFLAASITLDSIQGVLSGVARGCGWQRLATVINLGTFYLIGMPISVLCGFKLKLHAKGLWIGLICGMFCQSASLLLMTIFRKWTKLTAATV
What are the official names of this protein?
Protein DETOXIFICATION 18, AtDTX18, Multidrug and toxic compound extrusion protein 18, MATE protein 18, Protein LIKE ALF5.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SUB7_TRIVH
Sequence: MGFITKAIPLALAAASVINGAEIMETRAGVQTLADKYIVVMNDGMTDKDFDSHRSWVNRTHRRRLIRRGAKAMGGMKHTYRFPTGLKGYSGHFDEQMINEISKRADVKYIERDARVQINAIEQQDNVPSWGLARVGSKEPGGTTYYYDGTAGEGSTAYVIDTGTDIQHEEFEGRATWGANFVDDMDMDCNGHGTHVSGTIGGKTFGVAKKSNVVAVKVLDCNGSGSNSGVIMGMEWATKDAQQKGADKAVANMSLGGAFSQASNDAAAAIAQGGVFLAVAAGNDNVDAADSSPASEPSICTVAASTEQDGKADFSNFGQVVDVYAPGDSITSAKPGGGSQVLSGTSMATPHVAGLGAYLIGLGKGGGPGLCDTIKQMAIDVIQNPGASTTSKLINNGSGIGFLSFPLNIYEEQWSKLFDL
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 7.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LGB2_MEDTR
Sequence: MGFTEKQEALVNSSWELFKQNPGNSVLFYTIILEKAPAAKGMFSFLKDTAGVQDSPKLQSHAEKVFGMVRDSAVQLRATGGVVLGDATLGAIHIQKGVVDPHFVVVKEALLKTIKEVSGDKWSEELSTAWEVAYDALAAAIKKAMG
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin 2.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: VG60_BPML5
Sequence: MNVSFKILGYEIASIEFDFGEDDERELTPLDKGRKALSRWWVRGMVK
What are the official names of this protein?
Gene 60 protein, Gp60.
Protein: SPR2E_MOUSE
Sequence: MSYQQQQCKQPCQPPPVCPPKKCPEPCPHPQCPEPCPPPKCPEPCPEPCPPPSYQQKCPPVQPPPPCQQKCPPKSK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.  It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase.  All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity).
What are the official names of this protein?
Small proline-rich protein 2E.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_THISH
Sequence: MNIRPLHDRVIIKRMEEERTTAGGIVIPDSATEKPVRGEVIAVGKGKILENGEVRALDVKVGDKVLFGKYSGTEIKVDGQEVLVMREEDIMGVLEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSF_PROMS
Sequence: MAQSTVESKNRKDINNGKIPAKETILSPRFYTTDFEAMENMDLSINEEELEAICEEFRKDYNRHHFVRNSEFEGAAEKLDPETRELFVDFLEGSCTSEFSGFLLYKELSKRIKVKNPLLAECFAHMARDEARHAGFLNKSMSDFGLQLDLGFLTANKDYTYFPPRSIFYATYLSEKIGYWRYIAIYRHLEKNPDSKIFPLFNYFENWCQDENRHGDFFDALMKAQPRTVKSLSKKITIGGSTFTHPLFDYFHRFRYFLNNLPLTSKLWSRFFLLAVFATMYARDLGIKKDFYSSLGLDARDYDQFVINKTNETAARVFPVVMDVYDNSFYGRLDKIVENNKVLSDIANSDGNKVSKTFKKLPKYLSNGYQLLRLYLLKPLDSKDFQPSIR
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.