PharMolix/UniProtQA huggingface dataset:
Protein: GYRA_CAMJE
Sequence: MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRYHPHGDTAVYDALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPDVLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGRGRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNNLFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKNSSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKFDVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFVTDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRAINLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRVSRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDLMALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_CHLPB
Sequence: MAIKSRIRTIPDYPKKGIMFRDITTLLKDPVGFRLVIDQLSQHYIENGVDFDMIVGMEARGFIIGGALSYTLGKGFVPIRKPGKLPGEVVDQEYQLEYGTDKVEMHIDALEKGSRVLLVDDLLATGGTAMAGASLVEKVGGVIAEMAFIVNLPDIGGQKKLEEKGYKLFCLTEFEGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUHA_CAVPO
Sequence: MSDNTPWFEGIRFPMVCFSPEILREVRDKFLVKDEDTITVTYPKSGTNWLNEIVCLILSKGDPKLVQSVPNWDRSPWIEFTGGYELVKGQKDPRVYTSHLPLHLFPKSFFSSKAKVIYCIRNPRDALVSGYFFLSKMNVTEKPETLQQYMEWFLQGNVIYGSWFEHVRGWLSMREMENVLVLSYEDLIKDTRSTVEKICQFLGKKLKPEETDLVLKYSSFQFMKENEMSNFTLLPHAYTTEGFTLLRKGTVGDWKNHFTVAQAEAFDKIYQEKMAGYPPKLFSWEEC
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of 3-alpha-hydroxyl groups of neutral steroids.
What are the official names of this protein?
3-alpha-hydroxysteroid sulfotransferase, Alcohol sulfotransferase, HST1.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1L_MYCTO
Sequence: MSVRLADVIDVLDQAYPPRLAQSWDSVGLVCGDPDDVVDSVTVAVDATPAVVDQVPQAGLLLVHHPLLLRGVDTVAANTPKGVLVHRLIRTGRSLFTAHTNADSASPGVSDALAHAVGLTVDAVLDPVPGAADLDKWVIYVPRENSEAVRAAVFEAGAGHIGDYSHCSWSVAGTGQFLAHDGASPAIGSVGTVERVAEDRVEVVAPARARAEVLAAMRAAHPYEEPAFDIFALVPPPVGSGLGRIGRLPKPEPLRTFVARLEAALPPTATGVRAAGDPDLLVSRVAVCGGAGDSLLATVAAADVQAYVTADLRHHPADEHCRASQVALIDVAHWASEFPWCGQAAEVLRSHFGASLPVRVCTICTDPWNLDHETGRDQA
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: BH036_ARATH
Sequence: MEKMMHRETERQRRQEMASLYASLRSLLPLHFIKGKRSTSDQVNEAVNYIKYLQRKIKELSVRRDDLMVLSRGSLLGSSNGDFKEDVEMISGKNHVVVRQCLVGVEIMLSSRCCGGQPRFSSVLQVLSEYGLCLLNSISSIVDDRLVYTIQAEVNDMALMIDLAELEKRLIRMK
What are the official names of this protein?
Transcription factor bHLH36, Basic helix-loop-helix protein 36, AtbHLH36, bHLH 36, Transcription factor EN 6, bHLH transcription factor bHLH036.
What are the subcellular locations of this protein?
Nucleus.
Protein: ILVC_THEPX
Sequence: MAKMYYDKDADLNLLKNKKIAIIGFGSQGHAHALNLRDSGLDVIVGLYEGSKSKERAEKEGLRVYTVEEAAKVADIIMMLIPDEKQAKVYKESIEKNLTEGKALAFAHGFNIHFKQIVPPKNVDVFMVAPKGPGHLVRRVYQEGKGVPNLVAVYQDYTGKAFEIALAYAKGIGGTRAGVIETTFKEETETDLFGEQAVLCGGVTELMKAGFETLVEAGYQPEIAYFECVHEMKLIVDLIYEGGFSYMRYSISDTAEFGDYMTGKRIITEETRKEMKKVLSEIQSGKFAKEWLLENQVGRPQYNAIKDKEANHLIEKVGKGLREMMAWIKKE
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RCSA_SALTY
Sequence: MSTIIMDLCSYTRLGLSGYLVSRGVKKREINDIETVDELAIACGAHQPSVVFINEDCFIHTPSDSQQIKQIINQHPDTLFIVFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTLLGDILKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISDRMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR
What is the function of this protein?
Component of the Rcs signaling system, which controls transcription of numerous genes.  Binds, with RcsB, to the RcsAB box to regulate expression of genes.
What are the official names of this protein?
Transcriptional regulatory protein RcsA.
What is the protein family that this protein belongs to?
Belongs to the RcsA family.
Protein: HIS7_AKKM8
Sequence: MRNASCKRVTGETDISMELNLDGTGCAAVATGHAFFDHMLDLLARHSLMDLTLQARGDLEVDAHHTVEDVGIVLGECIKNALGDKKGIVRYGCSYLPMDETLTRVVMDLSNRPYVAFRIPEGGLPDAPNFPLTLCEEFCRALANNLRCNLHVEVLYGRDGHHIAESVFKGIAHALRQAAAIDPRAAGTLPSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMIA2_MYCTU
Sequence: MVGASGSDAGAISGSGNQRLPTLTDLLYQLATRAVTSEELVRRSLRAIDVSQPTLNAFRVVLTESALADAAAADKRRAAGDTAPLLGIPIAVKDDVDVAGVPTAFGTQGYVAPATDDCEVVRRLKAAGAVIVGKTNTCELGQWPFTSGPGFGHTRNPWSRRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRIPAAWTHLVGIKPQRGRISTWPLPEAFNGVTVNGVLARTVEDAALVLDAASGNVEGDRHQPPPVTVSDFVGIAPGPLKIALSTHFPYTGFRAKLHPEILAATQRVGDQLELLGHTVVKGNPDYGLRLSWNFLARSTAGLWEWAERLGDEVTLDRRTVSNLRMGHVLSQAILRSARRHEAADQRRVGSIFDIVDVVLAPTTAQPPPMARAFDRLGSFGTDRAIIAACPSTWPWNLLGWPSINVPAGFTSDGLPIGVQLMGPANSEGMLISLAAELEAVSGWATKQPQVWWTS
What are the official names of this protein?
Putative amidase AmiA2.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: VHUA_METVO
Sequence: MGKITIAPLTRLEGHGKVTIKLDDSGKPADVKLHITALRGFEQFVIGRPAEEVPRIVPRICGICQTAHHLASVKAVDAAWGAQIPSAAEKQRELMHLGNMIHSHALHFYYLAAPDFVLGPDADPAIRNIVGVIDAAPEVAKKAIAMRRVGQSMVEATGGKPIHPVTGIPGGLSKSMSEEKRDELLAEIDTMIQYGQDGLDLMKSLNEKYLDTINSLGVIDTWYLGLVKDGKHNFYGDTLRFVSPDGSEKMEFKPAEYLDYLGEHVVEHSYVKYPYNKKVGYPEGLYRVGPLAMINVCDSMSTPLAEEARKEFAETFGRPANQSIAYNQARLIELLSACERAKELLEDPEIVSTDVKAEVEPKAGNGVGVVYAPRGTLFHNYETDDNGIVTKANMIVATTHNVPTMEKAIQQAAEVLFKDN
What are the official names of this protein?
F420-non-reducing hydrogenase vhu subunit A.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
Protein: DNLJ_CHLPM
Sequence: MVGIDALRSEAERLRSDIERHNHLYYVEAKPELSDYDFDLLLDRLVQLEREHPELVTPDSPTQRVGGTITKEFPSVEHREPMLSLANTYSIGEVEEFVGRLNRLLEAEGAQGRDTVAELKFDGVAVSLLYRDGLLIRGATRGDGRRGDDITVNLKTVPSIPLRLGEFDGPFSAGEGREVEVRGEVLMRKEDFEALNDTRPEEDRFANPRNATAGTLKLQDSREVARRSLWFVAYYVSGLHDEDTRHVDRLKLLETAGFSTGNQYRLCHGIEEIEAFMQFWDEGRRALPYETDGVVVKLNDVRQWRLLGATSKSPRWAIAYKYPASRATTLLRDIVFQVGRLGTITPVAELEPVHIAGSTVARSTLHNFDEMRRLGVMPGDRVVIEKSGEVIPKVISVLLEERPPGLSAKELPTHCPDCGTPLVQPEGEVSWYCPNEEGCGAQIRGRVLHFASRNAMDIENLGESLVEQLVAKGMVKDPGDLYFLREEELAGLERMGEKSARNLLQGLLKSREQSFARLLFGLGIRHVGRATARELAKACSSIEVLKEASFEELSEVPDIGPVIARSIRDWFLKPAIPSLIEKLRRAGLPLAAEEPGPLVNTNFEGLTVVFTGGLQRHDRSSAGELVVARGGIVVSTVSKKTGLVVAGKEAGSKLEKARKLGLRIITEDEFDALL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PCKA_RHOPT
Sequence: MQETGVHNGAYGTDKFGLKNLKGVYWNFGAPQLYEHALKNGEAVLSSDGALVADTGVFTGRSPKDKFTVRDATTENTMWWGGNQSITAEQFETLYQDFLKHAEGMTLFAQDLYGGADPTFRIKTRVYTELAWHSLFIRTLLRRPERAELENFVPELTLIDLPSFRADPKRHGCRSENVVAIDFARKIVLIGGTQYAGEMKKSVFTTLNYYLPEKGVLPMHCSANVGPNGDTAIFFGLSGTGKTTLSADPNRTLIGDDEHGWGKDGVFNFEGGCYAKCIKLSAENEPEIYAASTRFGAVLENVVLGEIDRKPDFDDGSKTENTRSAYPLESIPNASLTGRAGQPKNVVMLAADAFGVMPPIAKLTPAQAMYHFLSGYTAKVAGTERGVTEPTPEFSTCFGSPFLPRDPSVYGNMLRELIAKHNVDCWLVNTGWTGGIYGTGHRMPIKVTRALLTAALDGSLRNVEFRTDPYFGFAVPTALPGVPSEILDPVKTWADKAAFDTTARKLVGMFQKNFAKFEAQVDAEVRAAAPDVKMAAE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTC5_AJECH
Sequence: MGGALSTDGAEQRASSVEELNQRLAHRFAAKCFEPLELTHLKENFFSRALDQHGIRYWNEEILSEFLGIPDGAGSAAAATSDGSLDAGPVIFRMVSYLGAFPFQNTMAPTVLTFESMVKVVVLLTERYGKVLKRGKKDRMKLLFGSLADVGRRDIITVLKEATEDSLESIGPSDPRSASPSTHNTGFLVDQPVNDEDEEDDDDLAIAALESLDAIEVFKHDQRIDKTVYESKISLTTFRRLLTLLLVTAPLRPLGRVSKFTTGLSKPSLDAVHEQVDSILAALDPGEASDGIGYKSFSKLVSTSLPYLFDPLTPLFEHLLFSKNLDLSRKRDSQTTNGLTSKPVPTPPSTPPLSPPLSPVISTGGFDSCILNPALLSHLSFFVSTNVHIPNIFRNRTHLHPVFSSTEHGESLTSFSHHVMTWQAPSILLVRGAVVSESSEEQLTTIGAYLPQPWKQTSSYSSRRSSEAPDPSTLPCLFELSPVHTVLQGSPSFSSLKSNMPVTHFSTKTGIAIGCMIPPSSRKSFGSDLHPKPAGGGSLLIDSALENATFIVSNGLNGPGVFLPPGISPVLSSTSLTASVPSMSSSNQNFTKSISIYNLEVWGIIPSTSLATQLDGSGSPIEKRDAISLQRAQWDFEAREAERRQAINMKVGGGESDAQTGRALLEMAGIIGDSYYSGHHRH
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_RHORT
Sequence: MAKRTLFGTDGVRGTANREPMTADTALRIGMAAGHLLRNGDHRHTVVIGKDTRLSGYMLEPALAAGFISVGMDVVLLGPLPTPAVAMLTRSLRADLGVMITASHNPFQDNGIKLFGPDGYKLSDDQEATIEALLDNGLEGHRAGPTALGKARRLDDCNGRYVEFVKSTFPRGRRLEGLRIVVDCAHGAAYRVAPKVLWELGATIVPIGVTPDGTNINKDCGSLHSRVMCETVVREGADLGVALDGDADRVVLCDEKGALVDGDQLLALIGRNWKRAGTLQGGGVVATVMSNLGLERFLKDEGLALARTPVGDRYVVEHMRAEGYNLGGEQSGHIVMSDFGTTGDGLMAALQVLSALVAEDRPASEVLDVFTPLPQLLRNVRVAGHDPRAILADPQVARAVSAGEGRLNGGGRLLIRKSGTEPLIRVMAEGEDEALVAQVVGDICAVIETASQ
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SECB_YERPA
Sequence: MSEQNNTEMAFQIQRIYTKDISFEAPNAPQVFQQDWQPEVKLDLDTASSQLAEDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSVAGIEGTQLAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAEGEVEGVEQRQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_HUMAN
Sequence: MFADRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGNLLGNDHIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAGAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGSNMKWSAAVLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFSGYTLDQTYAKIHFTIMFIGVNLTFFPQHFLGLSGMPRRYSDYPDAYTTWNILSSVGSFISLTAVMLMIFMIWEAFASKRKVLMVEEPSMNLEWLYGCPPPYHTFEEPVYMKS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COXX_EHRCJ
Sequence: MNSKCETIKPQVVNSILDYWNLLKPKIMYLVVLTGITGMIIAPGSIHPFIAIISTLCIALGSGAAGAINMWYDSDIDALMTRTKNRPIPAGKISKSSAIELGLVLSVISVTVMMISVNYISGILLAISIGFYSFAYTMYLKRRTPQNIVIGGIAGAIPPIIGWTSVTSSISIESLILFLIIFMWTPPHFWALSLLNYQEYEKAKIPMLPVTHGIFVTKVHILVYSIVLFIITLLPGLFLKDYLLYEICAIPLGITFLFHAFKVFTSSNYYKYKAMFTYSVAYLFILFICIILASF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU5M_CHLRE
Sequence: MFLLSVFFPLLGGLVNTSPIARFLGHRGSSIIAIGCMVVAFISSVVIYYEVVFMGCAVSVDVFGTWFSVGTFHAGWTFNFDLLTANMLFTVTGVSMAVHMYACDYMRQDPHLNLFLGYLSYFTGFMCVLVAADNLLVMLVGWEGIGVCSYLLIGYWSHRLSAVKSAQKAILVNRVSDGLLMWGVLWVWYHLGSLEYDLLNVYSASGFVGLSILIGAMGKSAQILFHVWLADAMEGPTPVSALIHAATLVTAGVYLLVRLHIHDEMFVIIVGSLTAFMAGVFGATQSDLKRVIAYSTCSQLGYMMVSLGLGETGGEASMGHLMTHASFKAALFLAAGMVISGNGGNQHIARYGGSAHSAMFTMLTLMVASLSLIGWPELSGFYSKETILNLAAICADPIADVAHTLLLLTAMLTSAYTTKLFYQCFMVDFSGSSVTPVRNVLPILAMAILLLDIMLKVWVGTNLLSGMLFFLPWGVKTLPFGLMVAGILTATAAVGSERFTLIRFCGSRWGFDQLFARSPVNPIFDLGRITWAIGDRGLLSVGNLRA
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DPO1_MYCTU
Sequence: MVTTASAPSEDRAKPTLMLLDGNSLAFRAFYALPAENFKTRGGLTTNAVYGFTAMLINLLRDEAPTHIAAAFDVSRQTFRLQRYPEYKANRSSTPDEFAGQIDITKEVLGALGITVLSEPGFEADDLIATLATQAENEGYRVLVVTGDRDALQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPRQYPDFAALRGDPSDNLPGIPGVGEKTAAKWIAEYGSLRSLVDNVDAVRGKVGDALRANLASVVRNRELTDLVRDVPLAQTPDTLRLQPWDRDHIHRLFDDLEFRVLRDRLFDTLAAAGGPEVDEGFDVRGGALAPGTVRQWLAEHAGDGRRAGLTVVGTHLPHGGDATAMAVAAADGEGAYLDTATLTPDDDAALAAWLADPAKPKALHEAKAAVHDLAGRGWTLEGVTSDTALAAYLVRPGQRSFTLDDLSLRYLRRELRAETPQQQQLSLLDDDDTDAETIQTTILRARAVIDLADALDAELARIDSTALLGEMELPVQRVLAKMESAGIAVDLPMLTELQSQFGDQIRDAAEAAYGVIGKQINLGSPKQLQVVLFDELGMPKTKRTKTGYTTDADALQSLFDKTGHPFLQHLLAHRDVTRLKVTVDGLLQAVAADGRIHTTFNQTIAATGRLSSTEPNLQNIPIRTDAGRRIRDAFVVGDGYAELMTADYSQIEMRIMAHLSGDEGLIEAFNTGEDLHSFVASRAFGVPIDEVTGELRRRVKAMSYGLAYGLSAYGLSQQLKISTEEANEQMDAYFARFGGVRDYLRAVVERARKDGYTSTVLGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVAMIQVDKALNEAQLASRMLLQVHDELLFEIAPGERERVEALVRDKMGGAYPLDVPLEVSVGYGRSWDAAAH
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: NXPH4_MACMU
Sequence: NCHVEYEKTNRARKHRPCLYDPSQVCFTEHTQSQAAWLCAKPYKVICIFVSFLSFDYKLVQKVCPDYNFQSEHPYFG
What is the function of this protein?
May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.
What are the official names of this protein?
Neurexophilin-4.
What is the protein family that this protein belongs to?
Belongs to the neurexophilin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMB_PASMU
Sequence: MSFNNQESENLPTFADQKRKTVEVAEFTAEGRYKRKVRSFVLRTGRLSEFQKNAMNQHWGFYGLEHQNQPFDFPAIYGNNNPVVLEIGFGMGHSLVDMALQNPERNYLGIEVHTPGVGACIAYAVEKGVKNLRIICHDATEILRDCIADHSLGGLQLFFPDPWHKAKHHKRRIVQPQFVNTITQKLTTGGFIHMATDWENYAEHMLAVLQQAEGLQNTSATHDYIPRPDFRPLTKFEQRGHRLGHGVWDLYYIKK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: PDXJ_AZOSB
Sequence: MIELGVNIDHVATLRQARRTWEPDPTWAAVEAHLGGADGITVHLREDRRHIQDDDVRRLRELTQIKLNLEMAATDEMVGIARSIKPEMAMLVPEGRHEVTTEGGLDIVSQEARLKDVIARLADAGIVTSVFIDAEIAQIDAAARIGARVCEIHTGPYAHAFHAQGRDAESPAVLAEIDKIRRAGEAICSHGMRFNAGHALNYYNVQPIARLPGIRELHIGHAIVSRAVFSGIREAVAEMKRLMREAAAG
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_VIBVY
Sequence: MTQLTVKALSEEIGTPVDRLLEQLADAGMKKSSSDQVSDEEKQKLLTHLKKEHGDTSGDAEPTRLTLQRKTRSTLSVNAGGGKSKDVQIEVRKKRTYVKRSAIEDEAKREAEEAAQREAEEAAKRAAEEAAKREAEEAAKREAEEKAKREAEEAAKREAEKSVDRDAEEKAKRDAEGKAKRDAEEKVKQEAARKEAEELKRRQEEEAKRKAEEESQRKLEEAREMAEKNKERWSAAEENKGDMEDTDYHVTTSQYAREAEDEADRKEEEARRRKKKTKSSAKASENDERGGPRVQRGGKGGRKGKLSKPKSMQHGFDKSAVVAKSDVVIGETIVVSELANKMSVKATEVIKIMMKMGAMATINQVIDQETAQLVAEEMGHKVVLRKENELEEAVLSDRDNMFEAVPRAPVVTIMGHVDHGKTSTLDYIRRTHVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTAMRARGAQATDIVVLVVAADDGVMPQTVEAIQHAKAAGVPLIVAVNKIDKEEANPDNVKNELSQYNVMPEEWGGENMFVHISAKQGTNIDQLLETILLQAEVLELTAVKEGMASGVVVESRLDKGRGPVATVLVQSGTLRKGDIVLCGQEYGRVRAMRDEIGNEVNEAGPSIPVEILGLSGVPAAGDEATVVRDERKAREVANYRAGKFREVKLARQQKSKLENMFSNMAAGDVAELNIVLKADVQGSVEAIADSLTKLSTEEVKVNIVGSGVGGITETDAVLAEASNAIILGFNVRADASARRAIEAASIDLRYYSIIYQLIDEVKQAMSGMLAPEFKQEIIGLAEVRDVFKSPKLGAIAGCMVTEGLIKRNAPIRVLRDNVVIYEGELESLRRFKDDVAEVKNGYECGIGVKNYNDVRVGDQIEVFETIEIKRTID
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGZE_YEAST
Sequence: MEMLLFLNESYIFHRLRMWSIVLWHSCVFVCAECGNANYRVPRCLIKPFSVPVTFPFSVKKNIRILDLDPRTEAYC
What are the official names of this protein?
Putative UPF0377 protein YGL260W.
What is the protein family that this protein belongs to?
Belongs to the UPF0377 family.
Protein: GATA_STRZT
Sequence: MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFVTIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFDATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAVASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTVKENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKETILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDATNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFADYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVGLQLIGPKHSEETIYQVAAAFEATTGYHKQQPVIFGGDN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: NORW_ECOLC
Sequence: MSNGIVIIGSGFAARQLVKNIRKQDATIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLHLFPQTWVTDIDAEARVVKSQNNQWQYDKLVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFCRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGIQATLDRQRNIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNTDIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLRWQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.