PharMolix/UniProtQA huggingface dataset:
Protein: KCC1A_EMENI
Sequence: MSFANMFNKLSGQPESYEKKSLYRFGRTLGAGTYGIVREADCSSGKVAVKIILKRNVRGNERMVYDELDLLQKLNHPHIVHFVDWFESKDKFYIVTQLATGGELFDRICEYGKFTEKDASQTIRQVLDAVNYLHQRNIVHRDLKPENLLYLTRDLDSQLVLADFGIAKMLDNPAEVLTSMAGSFGYAAPEVMLKQGHGKAVDIWSLGVITYTLLCGYSPFRSENLTDLIEECRSGRVVFHERYWKDVSKDAKDFILSLLQVDPAQRPTSEEALKHPWLKGESASDRDLLPEIRAYIARSRLKRGIEIIKLANRIEALKMQEEDEEDIPSAVDVQASEASDKSGLSPFPALSTENSNTHPASTGNGESGGTKKRSLSKIARGAIFREVVLAKVREMKENEEREKVEREARERAHS
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase (PubMed:2835766).  Required in nuclear division cycle for progression from G2 to mitosis.  Required for hyphal growth (PubMed:8898358).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase cmkA, CMPK, Multifunctional calcium/calmodulin-dependent protein kinase, ACMPK, CaMK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Protein: NUOH2_NITMU
Sequence: MEYAQQLFGDFFGPEWGPALFLLVKNVLLIVAIVLPLMLAVAYLTFAERKIIGYMQLRVGPNRVTFFGIPWLGGWAQPIADAVKAVMKEIIIPSGANKVLFVLAPILTFAPALAAWAVIPFSPDVVLADINAGLLYILAMTSMGVYGIIIAGWASNSKYAFLGAMRSAAQVVSYELAMGFALVCVLMMSQSLNLGDIVKGQQGASMLNWYLIPLFPMFLVYFISGVAETNRAPFDVAEGESEIVAGFHVEYSGMAFTVFFLAEYSNMILVAMLASIIFLGGWLPPVNVAPFTLVPGFIWLILKASFLLFCFLWFRATFPRYRYDQIMRLGWKVFIPITLVWIVVLGLVMQLPASIRGAFPLNLWFH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H 2, NADH dehydrogenase I subunit H 2, NDH-1 subunit H 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YHY2_YEAST
Sequence: MSVKEHNEEDIIGDELQNSRQLSIDCDSVKISLRNTYWTKDYTTGIKLFIKHMKRENDLLIKDIKFYNDFVNKFWKPTLNNLQKMEATNSMNSRLLEVMSKQFNIISTEQVERDCKIPLQELRDLNESFLREAENDLSSRYSAYIKDLVAAKEALIGCEKRVQSIYKLKKANTPVENSSSVFDNGKDSAPLTRLNFVCEFPYTLDERLKFEDCDQFMSFLQTLKGKVILEKSVFSVPGLSNQSFQGRSLIKELKKLEPRLNLSLFNIDRIGNEFIQLGIIQEYSLSFYSSKVSQFDQEKYYYWNSEVLATQESNGNAGNRKKKSYGELTHSDNEHEEKSNVSSIKTSISDWIRKVSQHDNDDCDAAGSTDMNKNEWKSLKQQLESSQDIFFSKCCQLEYSKVQLEKTIYDYCKNYSKMEDGIKRALESSNMMFQQKCEKFTDSPVCSLQEAQLPQETANADVRGFFLRDNGIPFRRWNILEASDPVDACKEISIKSEKFFCGSEINNELAALDTLGAIKIILRQIEKEPNANKVIQSWHRDIDFVRVSNLKRDLLGEFKGSKTTENTNSIITAHFFENSHSYVTNDLVGLIKLWLLELPDSLIPSNHYDDLIKAEKSLTSLCEQFPTSSLRFLQELANHFQLINSKYSLPPQTIQDLFRDNSDIDIPLAHHFVRRTGLQNPIDIKILSPTLSTFFINERTVETLQTLIANRITTATTATLTEPPTIIIKDTTAPIHSTPKPPPNDKDGHFIPRPFKTSSTPTTPERPKRKSGLFLPINVNDVPST
What are the official names of this protein?
Uncharacterized protein YHR182W.
Protein: HTPG_THIDA
Sequence: MSATSSKETLGFQAEVKQLLQLMIHSLYSNKDIFLRELISNASDAADKLRFEALSDAALFENDPELKIRIAFDRDARTLTISDNGIGMSRQEVIDHIGTIAKSGTREFFSQLSGDQKKDAALIGQFGVGFYSAFIVADRVTLTTRRAGLTAEHGVRWESEGAGDYTLETVEKPQRGTEIVLHLREGEDEFLSDWKIKSVIRTYSDHITLPIVMKKTEWKDGVETPTDEDETVNKASALWARPKKDISDDEYNEFYKHVAHDFEPPLAWSHNRVEGKQEYISLLYVPSHAPFDLYDREKRHGIKLYVRRVFIMDDAEQLMPQYLRFVRGVIDSADLPLNVSREILQSSRDIDAIKNGSVKKVLGMLEDLAENQPEKYVEFWKEFGKVMKEGPGEDFANKEKIAGLLRFASTHTDTDAQVVSLKDYVGRMKEGQTAIYYITADSFAAAQHSPHLEIFRKKGIEVLLLSDRVDEWLTGNLHEFDGKPLKSVAKGGLDLGELEDEAEKTAQKEAEESMKPLVERIKAMLGERVKDVRVTHRLTDSPACLVTGEGDMSANLERLLKAAGQAAPTVKPTLEINPSHALVTRLDSESDEDRFKDWANLLFEQALLAEGGQLDDPASFVRRLNGLLAMLPG
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B1_ORYSI
Sequence: MAPKAEKKPAEKKPAAGEEKSAEKAPAGKKPKAEKRLPASKASSKEGGAGDKKGRKKAKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAQEAARLARYNKKPTITSREIQTSVRLVLPGELAKHAVSEGTKAVTKFTSN
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TRMB_HELPH
Sequence: MPHFLAKLDFKPLKYPLIEGDFCFHKEFLSLKNPTKSCVYASFKDRIFLLQKIRRANDFLIKSEKTTPLKREILKQALRIYSQSFEVISHNLQENSKHASGKKALDLGTFEDFIQKNQAPILAEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLILESMPNYKCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDGLYFEDSLKLALKNFQCEIEIKKNAQIPVISKYEARWNKLKKDIYDLRIYSLELNETPFYNHAFDFSFDTITMSEKSVGTILKTKKIIQEGYFVHVCNIYENKGDFLVELSMGDFDWPVRLFVLLTENQIFYLNKSPLKTLNNHKAHLLLQNILSQKGIG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: YAAA_SALTY
Sequence: MLILISPAKTLDYQSPLATTRYTQPELLDHSQQLIQQARQLSAPQISRLMGISDKLADLNATRFHDWQPHFTPDNARQAILAFKGDVYTGLQAETFNDADFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENPRGKDLYQFWGDIITDKLNEALEAQGDRVVVNLASEEYFKSVKPKKLNAELIKPVFLDEKNGKFKVVSFYAKKARGLMSRFIIENRLTKPEQLTAFDREGYFFDEETSTQDELVFKRYEQ
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RL6_NEIMF
Sequence: MSRVAKNPVTVPAGVEVKFGTEALVIKGKNGELSFPLHSDVAIEFNDGKLAFVANNSSKQANAMSGTARALVSNMVKGVSEGFEKRLQLIGVGYRAQAQGKILNLSLGFSHPIVYEMPEGVSVQTPSQTEIVLTGSDKQVVGQVAAEIRAFRAPEPYKGKGVRYVGEVVVMKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL18_CLOB1
Sequence: MFKKNDRSQSRTRRHMRVRKKIFGTAERPRLSVYRSEKHIYAQLIDDVEGKTLVAASSSEKGFDGVGSNKEGAKLVGKMVAEKALEKGLKKVVFDRGGFIYHGRIKELAEGAREAGLDF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MURD_FRATH
Sequence: MFSFYFNDNKITKLLMVGYGSTGKSVCDFLANFIDITVDISQNDDEFVNYDLNSYDLITVSPGIPLNKSPYRALTKFKDKIVSDIDIFYQYIKDTKAKTIAVTGSNGKSTVVTMTDFVLKDLGYKSILVGNIGTPALNKIGEKFDYCVVEVSSFQINLFNCVRFDLGCIINVSPDHLDRYQNFEQYKQSKLNLAKFSNDFFVYDVHNGIKYAGEYQIIRGAIYRNSTKLLDIVETKLFGEHNLENIIVVLNILDRLGLDINQAIDSIKKFKGLEHRCKIVKKVNGTTYINDSKGTNVGATIAALNSITNSKNIILLLGGVAKGGDFSLMIKSLDKYVKYVYIYGADKEYIESYIKGYCKYQLCNNMKQAFELASQKANSNEIVLLSPACASFDEFSGYAQRGEVFQNLVAQLEQKS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHD_ECOLC
Sequence: MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCASVSYQQMHGFSAEQLRNTTHLVWATGGGMVPEEEMNQYLAKGR
What are the official names of this protein?
D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: COFG_THEVB
Sequence: MGDRTITYSPAFTLVPTYECFNRCTYCNFRQDIGTRGWLTLKAAAKQLAELDPQRVREILILSGEVAPNSPQRSKWLERLYDLAALALDQGFLPHTNAGPLTRAEMTALKAVNVSMGLMLEQLTPKLLQGVHRHAPSKDPQLRLHQLEQAGELGIPFTTGLLLGIGEAPQDWAETLTAIAEGHRRWGHIQEVILQPHSPGQQQAERLPPFDLKQLPQVVQWARSLLPEDITIQIPANLVTEPEVFRACLEAGARDLGGIVPLDHVNPDYPHTDLAVLKEQLQAWGWELVPRLPVYPQFVDWLPPPLKEKVKEIPV
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: RNY_STAAS
Sequence: MNLLSLLLILLGIILGVVGGYVVARNLLLQKQSQARQTAEDIVNQAHKEADNIKKEKLLEAKEENQILREQTEAELRERRSELQRQETRLLQKEENLERKSDLLDKKDEILEQKESKIEEKQQQVDAKESSVQTLIMKHEQELERISGLTQEEAINEQLQRVEEELSQDIAVLVKEKEKEAKEKVDKTAKELLATAVQRLAADHTSESTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDGRIHPGRIEDMVEKARKEVDDIIREAGEQATFEVNAHNMHPDLVKIVGRLNYRTSYGQNVLKHSIEVAHLASMLAAELGEDETLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKYGENETVINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLETLSESYDGVEKAFAIQAGREIRVIVSPEEIDDLKSYRLARDIKNQIEDELQYPGHIKVTVVRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y, Conserved virulence factor A.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MINE_ACIBS
Sequence: MAGFWSKLFSSEEKPSSAQTAKDRLKVIVASEQGLGRRLSQDKIDQMKKEIMQVVSRYVSGVGEQHIQMQVRSEANIEMLEMNINLPEER
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SYGA_PSEAE
Sequence: MSQTTPAVRTFQDLILALQNYWAEQGCVVLQPYDMEVGAGTFHTATFLRAIGPETWNAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVLKPNPENFQELYLGSLKAIGIDPLVHDIRFVEDNWESPTLGAWGLGWEIWLNGMEVTQFTYFQQVGGIECYPVTGEITYGLERLAMYLQGVDSVYDLVWTDGPFGKVTYGDVFHQNEVEQSTFNFEHANVPKLFELFDFYESEANRLIALELPLPTYEMVLKASHTFNLLDARRAISVTERQRYILRVRTLARAVAQSYLQARARLGFPMATPELRDEVLAKLKEAE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GT7_ORYSJ
Sequence: MRATTGARHLHPPWRRGLRHHRQSTMPPRASRGRLADAALFTAGAVLGSVLLLTLASPFSSSSSPSSGVGSGEVDRLGGGRTFYDDPGVAYTIDRPIVGWDEKRAEWLRAHPELAGGGGERVLMVSGSQPEPCGSPAGDSLLTRLLKNKLDYCRLNGVQLLYNTALLRPSMDRYWAKIPVVRAAMVAHPEAEWVWWVDSDAVLTDMDFRLPLSRYRDHNFVAHGWPHLVYESRSWTSLNAGVFLIRNCQWSLDFMDAWAAMGPDSPEYQHWGAVLTSTFKDKVFNESDDQSALVYMLLQSGSPWRDKVYLESDYYFEGYWLEIAGRLGNITERYEAMERGAAPLRRRHAEAEHASYAAARDAALAGAGLAESGVSGWRRPFVTHFTGCQPCSGHRNEHYTGKSCDEGIRRALSFADDQVLRAYGFRHAGPLSDAVSPLPFDHPTQTA
What is the function of this protein?
Probable glycosyltransferase that may be involved in the biosynthesis of xyloglucan.
What are the official names of this protein?
Probable glycosyltransferase 7, OsGT7.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 34 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: KAX2Z_CENLM
Sequence: TVIDVKCTSPKQCLPPCAKQ
What is the function of this protein?
Potent selective inhibitor of Kv1/KCNA voltage-gated potassium channels.
What are the official names of this protein?
Hongotoxin-5, HgTX5, Potassium channel toxin alpha-KTx 02.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MADS9_VITVI
Sequence: MGRGKIEIKRIENSSNRQVTYSKRRNGIMKKAKEITVLCDAHVSLVIFASSGKMHEYCSPSTTLIDILDRYHKQSGKRLWDAKHENLNNELDRIKKENDSMQIELRHLKGEDISSLHHKELMAIEDALEIGLASVRNKQMEFYKMVKKNQRILEEENKHLNYIVHHQGMPMEAGNVREVESGYHQRAVRDYNPQMPFAFRVQPIQPNLQERI
What is the function of this protein?
Probable transcription factor that may play role in specifying stamen and petal organ identity.
What are the official names of this protein?
Agamous-like MADS-box protein MADS9, PISTILLATA-like protein, VvPI, VviPI, Protein FLESHLESS BERRY, VvMADS9.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTPRU_DANRE
Sequence: MNTCAFLLILAVQIHADSVEGPTAGCTFDEDSDPSLCEFSQGEEDDFDWQLFRAHASPHSTSDLLRGSYMMVNSSQHAAGQRAQLLLQTLSENDTHCVQFSYFLYSRDGHSPGALRVYVRVNGGPLGIPVWNVSGSRGRQWHQVELAVSTFWPNEYQILLEATVDRKGYIAVDDILLLNYPCYKAPHFSRLGDVEVNAGQNATFQCVAAGRPSEAEKFLLERHNGEVSSGGSVKHLGRNRFAVSFQLEDVQKPEQDLYRCVTQSSRGSGVSNFAELIVKVPPSPIAPPQLLRAGSTYLIIQLNTNSILGDGPIIRREIEYRASLAPWSEILGVNMVTYKLWHLDPDTEYHISVLLTRPGEGGTGPPGPPLISRTKCAEPMRALRGLRASEIQSRQLTLQWEVPAFNLTRCHTYSVSLCYRYTTAGGGGGHNTTVRECLAVEHNTSRFTLRDLPPFHTIQIRLALANTEGKKEGKEVMFQTEEDIPGGIAPESLTFTPLEDMIFLKWEEPVEPNGLITQYEISYQSIESSDPGINVPGPRRTVSKLKNETYHMFSNLHPGTTYLISVRARTAKGFGQTALTEITTNISAPTFDYGDMPSPLSETENTITVLLRPAQGRGAPVSTYQVVVEEEAGRKVKRELGIQDCFPIPTSHGEAQARGAPHYYTAELPPSSLSEATPFTVGDNHTYNGYWNSPLDPRKNYLVYFQAMSNFRGETRINCIRIARKAACKDHQRALEVTQRSEEMGLILGVCAGGLVVLILLLGAIIIIIKKGRDYYSYSYYPRKPGNMNKTPITYRQEKSNMMGSMERSFTDQSTLQEDERMALSFMDTHTCSTRSDPRSSMNESSSLLGGSPRRQCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFDGWDINKKKDKTKGRHDTLMGYDRHRVKLHPLLGDPNSDYINANYIDGYHRSNHFIATQGPKQETVYDFWRMVWQENCFSIVMITKLVEVGRVKCCKYWPDESEMYGDIKITLLKTETLAEYTVRTFALERRGYSAKHEVCQFHFTSWPEHGVPYHATGLLAFIRRVKTSTPLDAGPVVVHCSVGAGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRINMIQTEEQYIFIHDAILEACLCGETAIPVNEFALAYKEMLRVDSQSNSSQLREEFQTLNSVTPHLDVEECSIALLPRNREKNRSMDVLPPDRALAFLVTTEGESNNYINAALMDSFHRPAAFIVTPHPLPGTTSDFWRLVFDYGCTSVVMLNQLNQSNSAWPCVQYWPEPGLQQYGPMQVEFLSMSADEDIITRLFRVKNVTRLQEGQLVVCQFQFLRWSAYRDVPDSKKAFLNLLASVQKWQRECGEGRTVVHCLNGGGRSGTYCASNILMEMIQYQNIVDVFYAVKTLRNAKPNMVETLEQYRFCYELVLEYLDCLEVR
What is the function of this protein?
Tyrosine-protein phosphatase which dephosphorylates CTNNB1.  May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity.  Functions in somitogenesis.  Functions as a regulator of the biochemical clock responsible for the segmentation of the presomitic mesoderm.
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase U, R-PTP-U, Receptor-type protein-tyrosine phosphatase psi, R-PTP-psi.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
What are the subcellular locations of this protein?
Cell junction. Cell membrane; Single-pass type I membrane protein.
Protein: RIBL_METBU
Sequence: MTRVLATGTFDLLHPGHVFFLRQARSFGDELYVLVARDSMIKHKAQPIVPEGQRLKMISAFGVVDKALLGSESDIFEPLKEINPDIIVLGHDQFFDTGELEKNLGERGFKAKVVRIDDAMKCELCSSGRIIKRVLERYGQNEE
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: BIP_XENLA
Sequence: MVTMKLFALVLLVSASVFASDDDDKKDDIGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIEKKTKPYIEVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGRKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRADKRAVQKLRREVEKAKRALSAQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDSDLKKSDIDEIVLVGGSTRIPKIQQLVKELFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIVGKLYGGAGAPPPEGAEGAEETEKDEL
What is the function of this protein?
Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity).  Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with dnajc10/ERdj5, probably to facilitate the release of dnajc10/ERdj5 from its substrate (By similarity).  Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR).  In the unstressed endoplasmic reticulum, recruited by dnajb9/ERdj4 to the luminal region of ern1/ire1, leading to disrupt the dimerization of ern1/ire1, thereby inactivating ern1/ire1.  Accumulation of misfolded protein in the endoplasmic reticulum causes release of hspa5/BiP from ern1/ire1, allowing homodimerization and subsequent activation of ern1/ire1 (By similarity).
What are the official names of this protein?
Endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein, GRP-78, Binding-immunoglobulin protein, BiP, Heat shock protein 70 family protein 5, HSP70 family protein 5, Heat shock protein family A member 5, Immunoglobulin heavy chain-binding protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RLMH_MARMM
Sequence: MRLRVAALGRIKSGPERTLVDDYLDRGTATGRAIGLGPFAESEIDTRSLKSSSDESRALAAGLDPGARIVLLDERGKALNSRQLARQIGQWRDEGCREAVFCIGGADGHDRSQLPQPDLMLSFGPAVFPHKLVRVMLAEQLYRAVSILAGTPYHRD
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMDG_ECOLI
Sequence: MKNSVAEH
What are the official names of this protein?
Protein YmdG.
Protein: PA2A2_BUNFL
Sequence: MNPAHLLVLSAVCVSLLGAAIVPPQPLNLIQFSSLIQCANGGSRATWHYADYGCYCGKGGGGTPVDELDRCCQTHDNCYGEAEKLTKCSPYYKTYKYDCSEGKLTCNDAPGSCERSVCDCDRVAAICFAGAPYNDKNFMINTETNCQ
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 2, svPLA2, PA2-II, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_CLOP1
Sequence: MALKKFNPTTPSRRQMTMPTFEEVTTNAPEKSLLVSLKKTGGRNAQGKITVRHHGGGAKRKYRIIDFKRNKDGIPAKVATVEYDPNRSAYIALVVYADGEKRYILAPVGLKVGDTVVSGPEADIKPGNALQLKHMPVGTFVHNIELQAGKGGQMVRSAGTSAQLMAKEGNYATLRLPSGEMRYVRIECKATVGTVSNTTHEIVNIGKAGRKRHMGWRPTVRGSVMNPCDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKNKKYSDRFIIKRRNAK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CLIT_CLINE
Sequence: LEDGIYRLRAVTTHNPDPGVGGEYATVEGARRPVKAEPNTPPFFEQQIWQVTRNADGQYTIKYQGLNTPFEYGFSYDELEPNAPVIAGDPKEYILQLVPSTADVYIIRAPIQRIGVDVEEGGQQNTLTYKFFPVDGSGGDRPAWRFTREE
What is the function of this protein?
Binds and inhibits cysteine proteinases.  Inhibits most strongly papain and cathepsin L, more weakly bromelain and cathepsin B while it is completely ineffective against cathepsin H.
What are the official names of this protein?
Clitocypin, Cysteine protease inhibitor.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I48 family.
What are the subcellular locations of this protein?
Note=Not secreted.
Protein: AZOR_RHIL3
Sequence: MSSILLLTSSPRADSLSTPIAVDLAEKLKSQNPGSVVVRRDLAANPLPHIDDLFTGAIRKPPEARTAEETVAVKTSDELVNELLAADTIVISTGLINFNIYSSLKTWIDNVARAGLTFKYTESGPVGLATGKKVYVVLASGGVYSQGPAAPLNHAVPYLKSVLGFLGISDIETIYVEGLAFGPEAAEKAIDAAKSRVQEIALAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: KGUA_XYLFA
Sequence: MRGTLYIVSAASGTGKSSIVNATLERDQQIALSISFTSRQPRPNERHAQHYYFVSADEFQRMIEAGDFFEYALVHDDWKGTAHQSVEPQLAAGHDVLLEIDWQGARQVRNKIPDAISIFILPPSRAALEERLRKRGQDSEEVIHRRLAAVHEEMAHYDEFDYTIINEHFETAVSEMSAIFTASRLRRQTQKVRHANLIRTLLTP
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_PSYCK
Sequence: MLLNMLKCKLHRARVTHAELHYEGSCGIDGDLLDLAGLRENESIDIYNVTNGKRFRTYAIRAEAGSGIISLNGAAAHMADLGDIVIICAYAHFDEVEASTYQPRLVYCNEDNTVKDTANIIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_IDILO
Sequence: MMKILLSNDDGVHAPGILALYQALKEVADVRVIAPDRNCSGASNSLTLHNPLRVRRLDNGFYSVNGTPTDCVHLGTNSPMAEDVDLVVSGINDSPNMGDDVLYSGTVAAAMEGRFMGLPAIAVSMGGRGHDYYDTAGRVVAEIVANMENDPLRLDTVLNINVPYTTYDKLKGTRVTKLGRRHRAETMVHDRDPFGSEIFWYGPIGHHASDEPNTDFTAIHEGYISITPLSLDMTAQRHTDTLTDWLEQQK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.