PharMolix/UniProtQA huggingface dataset:
Protein: ERA_SALTI
Sequence: MSTDKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGPYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGMNVDTIASIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: RL19E_PYRFU
Sequence: MNTLKMQRRIAAEILKCGENRIWIDPERIDDVASAITREDIKRLIKEGVIKKKPIKGQSRYRAKIRHEQKKKGRHRGPGSRKGKKTARMGKKELWIKTIRALRKELRKLKAQKKIDRKTYRMLYIRAKGGQFKNKHQLYLFLEEHGLLKK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L19e, Large ribosomal subunit protein eL19, PfeL19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
Protein: TGT_BORBU
Sequence: MFSVIKNDKHFNARVGFLNLPHGRVDIPCFMPVGTLGAMKGLKHAVLEKLECNLMLANTYHLYLRLGIKTVEKYVGLHNFTIWNKNFLTDSGGFRVFSFSDLRKIDLKGVHFKSHIDGSYHYFTSEGIFAMQEIFGSDIIMPLDICSSYGIDYNEANLYTNITTNWASSTFKSSKNRKEGYNGLLFLITQGNFFKDLRKRSINDILELDSPGIAIGGISVGEPREKYLEILEYSFLLIPKEKPRYVMGIGTPHYILNAIYYGIDIFDCFNPARITRHGSLLTDNGIMCIGRKEYKDDTSKVEKNCICTLCKRYSRGYLRHLIKSKELFGIVLASEHNIHYMFRLISKIRAAILNDDFLNFRTSYLKKYEEENFDE
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: YKUJ_BACSU
Sequence: MSQLMGIITRLQSLQETAEAANEPMQRYFEVNGEKICSVKYFEKNQTFELTVFQKGEKPNTYPFDNIDMVSIEIFELLQ
What are the official names of this protein?
Uncharacterized protein YkuJ.
Protein: HEM1_CANAL
Sequence: MESITKVSMSVCPFVRSTSTQALRQLSQTSGALANQARQCPIAGNAIRAKEISIRSYSSATKPARATAATPSTPEATFNVTSSFELGSKETAFDYNGYLGNELEKKRSDKSYRYFNNINRLANEFPKAHRTQEEDKVTVWCSNDYLGMGKNENTLKEMKRVLDKYGSGAGGTRNIAGHNSHAIKLESELAALHKHDAALVFSSCFVANDAVLSLLGQKIKDLVIFSDELNHASMIQGIRNSRARKHIFKHNNLADLESKLAQYPKSTPKLIAFESVYSMCGSIAPIEAICDLAEKYGALTFLDEVHAVGMYGPHGAGVAEHLNFEAHLKSGIERPEITTVMSRVDMVTGTLGKAYGVVGGYITGKTNLIDWFRSYAPGFIFTTSLPPAIMAGCSASIRYQRATLKDRIAQQKNTRLVKNNLNELGIPVIPNPSHIVPVLVGNAADAKRASDLLLNKHDIYVQAINFPTVPIGEERLRITPTPGHGPELSKQLVEAVDSVFTELNLNRINDWKKLGGLVGVGVEGAAKVEHIWTEEQLALTDADLNPNVVNPAISPLDVSSGIST
What is the function of this protein?
Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
What are the official names of this protein?
5-aminolevulinate synthase, mitochondrial, 5-aminolevulinic acid synthase, Delta-ALA synthase, Delta-aminolevulinate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: C1QC_MOUSE
Sequence: MVVGPSCQPPCGLCLLLLFLLALPLRSQASAGCYGIPGMPGMPGAPGKDGHDGLQGPKGEPGIPAVPGTRGPKGQKGEPGMPGHRGKNGPRGTSGLPGDPGPRGPPGEPGVEGRYKQKHQSVFTVTRQTTQYPEANALVRFNSVVTNPQGHYNPSTGKFTCEVPGLYYFVYYTSHTANLCVHLNLNLARVASFCDHMFNSKQVSSGGVLLRLQRGDEVWLSVNDYNGMVGIEGSNSVFSGFLLFPD
What is the function of this protein?
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.  The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
What are the official names of this protein?
Complement C1q subcomponent subunit C.
What are the subcellular locations of this protein?
Secreted.
Protein: YOPN_YERPE
Sequence: MTTLHNLSYGNTPLHNERPEIASSQIVNQTLGQFRGESVQIVSGTLQSIADMAEEVTFVFSERKELSLDKRKLSDSQARVSDVEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLSQLKAYLEGKSEEPSEQFKMLCGLRDALKGRPELAHLSHLVEQALVSMAEEQGETIVLGARITPEAYRESQSGVNPLQPLRDTYRDAVMGYQGIYAIWSDLQKRFPNGDIDSVILFLQKALSADLQSQQSGSGREKLGIVISDLQKLKEFGSVSDQVKGFWQFFSEGKTNGVRPF
What is the function of this protein?
Plays a major role in regulation of the low-calcium response.  Seems to sense the calcium concentration and to transmit a signal to shut off yop transcription when the calcium concentration is high (By similarity).
What are the official names of this protein?
Outer membrane protein YopN, LcrE, Yop4b.
What is the protein family that this protein belongs to?
Belongs to the HrpJ/YopN family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: RL15_ACTSZ
Sequence: MRLNTLSPAEGAKHSAKRLGRGIGSGLGKTGGRGHKGQKSRTGGKVRRGFEGGQMPLYRRLPKFGFTSKIAAVTAEIRLNDLTKVDGNIVTLEALKAANVITKDIQFAKVILAGEINNAVTIRGLRVTQGAKAAIEAAGGSVEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: QUEA_CLOBH
Sequence: MKVKDFDFYLPEELIAQHPIEKRDEARLLVLDKETGEIEHKIFKDILDYLTPNDCLVLNNTRVLPARLIGAKEETGGKMEFLLLKRKEKDVWETLVKPGKRAQIGARFIFGNGELKAEVIGMGEEGSRIVKFYYEGIFEEILDQLGQMPLPPYIKEKLDDKEMYQTVYSKEEGSAAAPTAGLHFTEELLKKIEEKGVKLAFLTLHVGLGTFRPVKVEDIQEHVMHSEYYKMDKKTAEIINDTKENGGRVIAVGTTSCRTLETIGAIEGKVGEQSGWTDIFIYPGYKYKVVDALITNFHLPQSTLLMLVSALAGRDNIMNAYNVAVEKEYRFFSFGDAMFIK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y872_PYRAB
Sequence: MGEIIEVIYENGILKPLKKLPFKEGEKLIVEVKSTNKEKLLEELKGSIKLGKKVTITRILELEDEVWSSI
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.
What are the official names of this protein?
Putative antitoxin PYRAB08720.
What is the protein family that this protein belongs to?
Belongs to the UPF0165 family.
Protein: NINJA_ARATH
Sequence: MDDDNGLELSLGLSCGGSTGKAKGNNNNNAGSSSENYRAEGGDRSAKVIDDFKNFLHPTSQRPAEPSSGSQRSDSGQQPPQNFFNDLSKAPTTEAEASTKPLWVEDESRKEAGNKRKFGFPGMNDDKKKEKDSSHVDMHEKKTKASHVSTATDEGSTAENEDVAESEVGGGSSSNHAKEVVRPPTDTNIVDNLTGQRRSNHGGSGTEEFTMRNMSYTVPFTVHPQNVVTSMPYSLPTKESGQHAAATSLLQPNANAGNLPIMFGYSPVQLPMLDKDGSGGIVALSQSPFAGRVPSNSATAKGEGKQPVAEEGSSEDASERPTGDNSNLNTAFSFDFSAIKPGMAADVKFGGSGARPNLPWVSTTGSGPHGRTISGVTYRYNANQIKIVCACHGSHMSPEEFVRHASEEYVSPESSMGMTAASAHT
What is the function of this protein?
Acts as a transcriptional repressor.  Negative regulator of jasmonate responses.  Connects the JAZ proteins and the non-JAZ protein TIFY8 with the TOPLESS corepressors.
What are the official names of this protein?
AFP homolog 2, Novel interactor of JAZ.
What is the protein family that this protein belongs to?
Belongs to the Ninja family.
Protein: PYRH_CENSY
Sequence: MAKKRIVIKLSGSAFGGDDGKVLREYAAFLSGISGSWQPVVVAGGGRVARQYIANARSSGADETTLDEIGIGVSRLNARLLICALGAKAHPYPPATLKEVRHAVDGGLVVIAGGLHPGQSTNGTAALIAEKVGAAQFLNATDVDGVYDRDPNKHSDARMLRKIGLGELRKMLAREDSVAGGYDLMDLVALKVIERSRIRTRILRADVNVLKKAVRGTAAGTELVLPDS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXS_ACIBT
Sequence: MSFPADSVGLVTPQKFQFEEPLHLECGRVLPRFELMVETYGTLNADKSNAILICHALSGHHHAAGYHHEDDKKAGWWDSCIGPGKAIDTNKFFVVALNNIGGCSGSTGPTSPNPENDNRPYGPDFPLVTVRDWVKTQAMLSDRLGISVWYAVVGGSLGGMQALQWSVDYPDRLQKCVVIASAPKLSAQNIAFNEVARQSILSDPDFHHGRYLENDSYPKRGLILARMVGHITYLSEEAMKQKFGRDLKSGKFMYGFDVEFQVESYLRYQGEQFSRNFDANTYLIMTKALDYFDPSREYGHSLTEAMSKTKCQFLIVSFTTDWRFAPSRSQEIVDALITNHKPVSYLDIDAEQGHDSFLFPIPLYVKTLRAFLGGEEHLKSTSLEAS
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_SULSY
Sequence: MVIDKNKIEQAIRLFLEGIGEDPNREGLRDTPKRVAKMWEEFESYREMNMTIFEEVGSYDEMVVVRDIQFYSLCEHHLLPFFGKAHVAYIPDKKVCGLSKIVRVVNKFSYRPQVQERLTAEIAEYLEKELQPKGVAVVMEAVHLCMAMRGVRNPESITVTSKLTGRFLECQKTREEFLNLINSHKKM
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: ARO12_TALMQ
Sequence: MAEPTKISILGRESIVAEYGIWGTYIVQDLLTNLPSTTYVLVTDTNLGSIYREKFAKVFNEAAAALSPAPRLLTKEIPPGENSKSRQGKADIEDWMLQQTCGRDTVIIALGGGVIGDLLGFVASTYMRGIRFVQVPTTLLAMVDSSIGGKTAIDTPLGKNLIGAIWQPHRIYIDIDFIDTLPEREFINGMAEVIKTAAISDEKEFAALEQHADAILKAARSKAGKGRFDSVRQVLKDRIVASARHKAYVVTADEREGGLRNLLNLGHSIGHAIEAILSPQVLHGECVAIGMVKELELARYLGILKPIAVSRMVKCLSKYGLPTSLKDARVRKHTAGKHCSLEQLMANMALDKKNDGPKKKVVLLSAIGKTYEPKASVVSNEDIRVVLAPSIEVIPGVPKNLNVVCAPPGSKSISNRALVLAALGSGTVRVKNLLHSDDTEVMLNALERLGAATFAWEDEGEVLVVNGNGGKMQASPTELYLGNAGTASRFLTSVATLSGKGSVDYNILTGNNRMKQRPIGDLVDALTVNGAQVEYLEKAGSLPLKIAASGGFKGGRINLAAKVSSQYVSSLLMCAPYAKEPVTLKLVGGKPISLSYIEMTTAMMRSFGIDVQKSTTEEWTYHIPQGSYTNPPEYVIESDASSATYPLAIAAVTGTTCTVPNIGSASLQGDARFAVEVLRPMGCNVEQTATSTTVTGPADGVLRPLPNVDMEPMTDAFLGASVLAAIAQGKGGNNTTRIYGIANQRVKECNRIEAMRVELAKFGVVCREHPDGLEIDGINRSSLRHPAGGVFCYDDHRVAFSFSILSLVAPTSTLILEKECVGKTWPTYWDALKQKFGVQLEGKELAESEVTHGSADRSNASIIIIGMRGAGKTTTGRWAAKALNRKFIDLDVELEQTEGKTIPDLIKERGWQGFRDAELSLFKRALAERPTGHVFACGGGIVEIAEARKILVDYHKNKGNVLLVMRDIKKVMEFLNIDKTRPAYIEDMMSVWLRRQPWYQECSNVQYYSRHSSSPELALAMDDFGRFIQFVSGQTDYLAAIRKKHLSFFVSLTLPDLRESGDLLRTVASGSDAVELRVDLLKDPSSDSVIPSAEYVAEQISFYRSRVSLPIVFTIRTVSQGGKFPDDAHDAALELIMLAIRSGCEFIDLEITFPEDLLRKVTESKAHAKIIASHHDPRGKLNWANGSWIQYYNKALQYGDIIKLVGVAETLKDNTSLKDFKDWAEQAHPDVPVIAINMGDKGQLSRMLNGFLTPVSHPALPFKAAPGQLSAAEIRRGLSIMGEIPAKKFAVLGKPVSASRSPPMHNTLFEQNGLPHVYTRLETDKAQDVKEFIRSPDFGGASVTIPLKLDIIPLIDEILNEAEIIGAVNTIIPVEGKDGSTRLVGRNTDWSGIVRCLREAGAHSNEGKSSALVIGGGGTARAAIYALHHMGFSTIYVLGRSPEKIQNMASTFPTGFDIRVLEHANDVESIPRVAVGTIPGDKPIESNIREILCTIFQRSGSAGDESGVLLEMAYKPSVTPLIQLASDYGWTTIPGLEALVGQGVYQFEYWTGITPVYEVARNAVLGTNETK
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM02_ARATH
Sequence: MRPGRARALRQFTLSTGKSAGRNSSGRITVFHRGGGSKRLLRRIDLKRSTSSMGIVESIEYDPNRSSQIAPVRWIKGGCQKKMNTIEKFAPPRKILEPTTNTISGLFSFSFLPGKVDKRKVACFSPGLMAAYVVVGLPTGMPPLSSSKSAFASKGAGSTKTLVKDVFFSAFSSPKAKRETASLAFASSFGFPRIAVAGAKPAFFAPRMRQKVRGKSTFSLCEVQKGRTHSILWAHRIKGKAGLSWQSFRRQDTLGLVGAAGHKKSKPKTDQGNLPAKPIGERAKQLKALRGLRAKDGACKVDRAPVTYIIASHQLEAGKMVMNCDWSKPSTSSFLQSAQNDHPKPLFTV
What are the official names of this protein?
60S ribosomal protein L2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPOZ_ALKOO
Sequence: MLYPPINELLDKVDSRYTLVVAAAKRARQLIDGAVPKIEMPYSKKPVSIATQEIYESYVLYTSGEDETDIE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SLCC_CHRSD
Sequence: MSDVLISEFMDEAAVADLERDCSVTFDATLVDDRARLLSSGAGVRALIVRNRTRVDRELLARFPDLRAVGRLGVGLDNIDVDACRESDIAVLPATGGNTVSVAEYVLTGIFMLRRGAYLSTPRVLAGEWPRQALMGHETQGATLGLVGFGGIARDLARRAQCLGMQVMAHDPFVPADDAAWQTVERAERLATLLEKADAVSLHVPLSEGTRHLIDGEALATMKPGSLLINTARGGIVDERALAASLRDRHLGGAMLDVFEEEPLTADSVLSGVEGLIATPHIAGVTHESNERISWITVDNVRRALGVRA
What is the function of this protein?
Dehydrogenase of the (R,S)-sulfolactate degradation pathway that only acts on the (S)-enantiomer of 3-sulfolactate.  Together with ComC, provides a racemase system that converts (2S)-3-sulfolactate to (2R)-3-sulfolactate, which is degraded further by (2R)-sulfolactate sulfo-lyase.  Specific for NAD.  Also able to form sulfolactate from sulfopyruvate.
What are the official names of this protein?
(S)-sulfolactate dehydrogenase, (2S)-3-sulfolactate dehydrogenase, (S)-sulfolactate oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: SYG_STRAW
Sequence: MAADKIDTIVSLSKRRGFVFPCSEIYGGQKAAWDYGPLGVELKENIKRQWWRYMVTSREDVVGIDSSVILATEVWVASGHVATFSDPLTECTSCHKRYRADHLEEAYEAKHNRSPENGLADINCPNCGNKGQFTEPKQFSGLLSTHLGPTQDSGSVAYLRPETAQGIFTNFAQVQQTSRRKPPFGIAQMGKSFRNEITPGNFIFRTREFEQMEMEFFVKPGEDEKWQEFWMQERWNWYTGLGLREENMRWYDHPAEKLSHYSKRTADIEYRFQFGGNEWGELEGVANRTDYDLSAHAKASGQDLSYFDQEAGERWTPYVIEPAAGVGRAMLAFLLDAYVEDEAPNAKGKMEKRTVLRLDPRLSPVKVAVLPLSRNPELSPKAKGLATALRQHWNIEFDDAGAIGRRYRRQDEIGTPFCVTVDFDTLDDNAVTVRERDSMKQERVSLDQIEGYLAARLIGC
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP4C2_CAEEL
Sequence: MLEEDAAGPDQLGPNDLDRQIEIAMRCELICETQVKSICAKVREILIEEANVQVIDTPVTICGDIHGQFHDLMELFRVGGSPPNTNYLFLGDYVDRGYNSVETFILLMLLKCRYPDRITLIRGNHESRQITQVYGFYDECVRKYGSGQVWKHCTEIFDYLSLAAVIDGKLFCVHGGLSPSIATLDQIRVLDRKIEVPHEGPMCDLLWSDPEEGCSGWGISPRGAGYLFGGDAAELFCENNDFLRICRAHQLVMEGYKLHFRKRVVTVWSAPNYCYRCGNVAAIMEVTEENIDSDPVFEVFEAATVENRGEPKKQPIAQYFL
What is the function of this protein?
Protein phosphatase which seems to be involved in larval development but not essential for embryogenesis.
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 catalytic subunit 2, PP4C-2.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
Protein: U161_ARATH
Sequence: MAVVISIHRPYVTLTISKNRNPLKPHRQFNESCLRFDHLPRNTKNQLRCLSAKSTPSKPDPASPQDGEELESVGVKAALAMLRFYKREISPVLPRSCRYVPTCSEYSMEAYKKYGVLKGTVLTTWRLCRCNPLGGSGFDPPRWFGESGIKLREGDEEEEDNYDDEDQRKI
What are the official names of this protein?
UPF0161 protein At3g09310.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
Protein: RSMA_SULSY
Sequence: MNKIKPKKRLGQHFLISKNVIEKIVDEINISKEDIIVEIGPGTGALTEEILLRNPKILYAIEIDTSVHPVLEEKFSIYSNFKLIKSDFFDVNLYELISDEEKIKLVGNLPYNVASLMIIDCAFKLDILEFCVFMIQKEVAEKLIAKPKTKDYTFLSVFIQTFFDIKYVMSVPARFFNPPPKVTSAVVKLTPKQNIAINNVKKYKNFISHLFQNRRKMIKSKIEEEMLNKAGISPNLRAEELSVEDFIRIFGVVENDDR
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMA_YERPN
Sequence: MLEAKNLTCIRDDRCLFQQLSFCIAPGEIVQIEGPNGAGKTSLLRILAGLAEADEGQVNWRDKNIRRDRAKYHQDLLFLGHQPGIKSVLTPFENLLFYQSVFQKVDSAAIWQALAQVGLVGYEDLPVSQLSAGQQRRVALARLWLSPAPLWILDEPLTAIDKQGVSTLLALFVQHAAKGGMVLLTTHQDLGAVSHNVRKICLANTQEKSCLSACCAVN
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VL1_HPV47
Sequence: MAVWHSANGKVYLPPSTPVARVQSTDEYIQRTNIYYHANTDRLLTVGHPYFNVYNNNGTTLEVPKVSGNQHRVFRLKLPDPNRFALADMSVYNPDKERLVWACRGLEIGRGQPLGVGSTGHPYFNKVKDTENSNSYITNSKDDRQDTSFDPKQIQMFIVGCTPCIGEHWDKAEPCGEQQTGLCPPIELKNTYIQDGDMADIGFGNINFKALQHSRSDVSLDIVNETCKYPDFLKMQNDVYGDACFFYARREQCYARHFFVRGGKTGDDIPGAQVGNGNMKNQFYIPGATGQAQSTIGNAMYFPTVSGSLVSSDAQLFNRPFWLQRAQGHNNGILWANQMFVTVVDNTRNTNFSISVYSQAGDIKDIQDYNADNFREYQRHVEEYEISVILQLCKVPLKAEVLAQINAMNSSLLEEWQLGFVPTPDNPIQDTYRYLESLATRCPEKSPPKEKVDPYKGLNFWDVDMTERLSLDLDQYSLGRKFLFQAGLQQTTVNGTKTTPYRGSIRGTKRKRKN
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PD1L1_MOUSE
Sequence: MRIFAGIIFTACCHLLRAFTITAPKDLYVVEYGSNVTMECRFPVERELDLLALVVYWEKEDEQVIQFVAGEEDLKPQHSNFRGRASLPKDQLLKGNAALQITDVKLQDAGVYCCIISYGGADYKRITLKVNAPYRKINQRISVDPATSEHELICQAEGYPEAEVIWTNSDHQPVSGKRSVTTSRTEGMLLNVTSSLRVNATANDVFYCTFWRSQPGQNHTAELIIPELPATHPPQNRTHWVLLGSILLFLIVVSTVLLFLRKQVRMLDVEKCGVEDTSSKNRNDTQFEET
What is the function of this protein?
The PDCD1-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and escape destruction by the immune system, thereby facilitating tumor survival (PubMed:12218188, PubMed:27281199).  The interaction with PDCD1/PD-1 inhibits cytotoxic T lymphocytes (CTLs) effector function (PubMed:12218188).  The blockage of the PDCD1-mediated pathway results in the reversal of the exhausted T-cell phenotype and the normalization of the anti-tumor response, providing a rationale for cancer immunotherapy (PubMed:12218188).
What are the official names of this protein?
Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. BTN/MOG family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Recycling endosome membrane; Single-pass type I membrane protein.
Protein: RLMH_LISMF
Sequence: MNIQIVTVGKLKEKYLVQGIAEYLKRLSAYAKVTIVEVPDEKAPEVLSDAEMKQVKDKEGARILAKIPDDAHVIALAIDGKMKSSEEFAADLDKLATYGKSKVTFVIGGSLGLSEAVLKRSNERISFGRLTLPHQLMRLVLVEQVYRAFRIVRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_YERPP
Sequence: MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHLA_ARATH
Sequence: MYYHNQHQGKSILSSSRMPISSERHPFLRGNGTGDSGLILSTDAKPRLKWTPDLHERFVEAVNQLGGGDKATPKTIMKVMGIPGLTLYHLKSHLQKYRLSKNLNGQANSSLNKTSVMTMVEENPPEVDESHSESLSIGPQPSMNLPISDALQMQIEVQRRLHEQLEVQRHLQLRIEAQGKYLQSILEKAQETLGRQNLGAAGIEATKAQLSELVSKVSADYPDSSFLEPKELQNLHHQQMQKTYPPNSSLDSCLTSSEGTQKAPKMLDNRLGLRTYIGDSTSEQKEIMEEPFFHRMELTWAEEESLRENHNRPYLSTMVNNAEPRISSSRRSPGRLSIGVGLHEHRGRSSNNSEYTEERFNENNEDCKLETHTRTALDLNTHDENYGTTRPKQFDLNGFSWN
What is the function of this protein?
Transcription factor that may act on the GAL1 promoter (PubMed:12008900).  Acts redundantly with MYR2 as a repressor of flowering and organ elongation under decreased light intensity (PubMed:21255164).  Represses gibberellic acid (GA)-dependent responses and affects levels of bioactive GA (PubMed:21255164).
What are the official names of this protein?
Myb-related protein 1, Myb family transcription factor PHL10, Protein PHR1-LIKE 10.
What is the protein family that this protein belongs to?
Belongs to the MYB-CC family.
What are the subcellular locations of this protein?
Nucleus.