PharMolix/UniProtQA huggingface dataset:
Protein: ERB1_PICST
Sequence: MSKSSKVGMTDVSVPKSAVLKKRNQREVEAEVDESSEEEFEMDGLLDAEASEDDEEDEENSEDDEEEDSDKELNELLGEEEDPSDYDSENFSDEPQESDTRSITDAISGVKIRSLSDISSQDKQEFHTKYSDGSERIIKPEIEPVYDSDDSDAENFNTIGDIPLSAYDEMPHLGYDINGKRIMRPAKGSALDQLLESIDLPQGWTGLLDQNTGSSLNLTDEELELIRKIQQQENTDANIDPYEATIEWFTSKVEVMPLTAVPEPKRRFVPSKHEAKRVMKIVRAIREGRIIPPSKVKEQIEEERLNYDLWNDDDIAVEDHIMNLRAPKLPPPTNEESYNPPEEYLLTEEEKKQWESLDPADRERNFLPQKFGALRKVPGYQESVRERFERCLDLYLAPRVRHNKLNIDPESLIPELPSPKDLRPFPIRCSTVYQGHTDKIRTISIDPQGLWLATGSDDGSVRIWEILTGRQVFNVQLINKEINDEDHIESLEWNPDSQTGILAVCAGENIYLVVPPIFGFDIENMGRLRIESGWGYDTFGNKTKEEKFKNDEGNEDEDDEDDSATSTAVKKDVARWFPPNQEQTKLGISAIIQCRKTVKKVSWHRKGDYFVTVSPDSKNTAVLIHQLSKHLSQSPFKKSKGIIMDAKFHPFKPQLFVASQRQVRIYDLAQQVLVKKLMPGVRLLSTIDIHPRGDNLLASSYDKRVLWHDLDLSATPYKTLRYHEKAVRSIKFHKGNLPLFASASDDGNIHIFHGTVYDDLMTNPLLVPLKKLTGHKIVNSIGILDLIWHPKEAWLFSAGADGTARLWTT
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ERB1, Eukaryotic ribosome biogenesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: MIAA_STRTD
Sequence: MKTKLIVVAGPTAVGKTALGIELAERFNGEIISGDSQQVYRQLNIGTAKATPEEQAAAVHHLIDVRDVDESYSAYDFVTEAQAAITDIVSRGKLPIIVGGTGLYLQSLLEGYHLGGQVDQNQVLAYRSELEQLSDQQLFEKIDSLGIEIKEINRRRAIRALELYRFSDNLENTETCYEPFIIGLDDERSLIYDRINTRVDKMVELGLLEEAKWLYDNFSEAQSARGIGYKELFPYFSGEQTLDEALEKLKQNTRRFAKRQLTWFRNRMTVSFYQISSPEYPENVIQDLAIFLNEEEGEK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: NAC87_ARATH
Sequence: MAVVVEEGVVLNHGGEELVDLPPGFRFHPTDEEIITCYLKEKVLNSRFTAVAMGEADLNKCEPWDLPKRAKMGEKEFYFFCQRDRKYPTGMRTNRATESGYWKATGKDKEIFKGKGCLVGMKKTLVFYRGRAPKGEKTNWVMHEYRLEGKYSYYNLPKSARDEWVVCRVFHKNNPSTTTQPMTRIPVEDFTRMDSLENIDHLLDFSSLPPLIDPSFMSQTEQPNFKPINPPTYDISSPIQPHHFNSYQSIFNHQVFGSASGSTYNNNNEMIKMEQSLVSVSQETCLSSDVNANMTTTTEVSSGPVMKQEMGMMGMVNGSKSYEDLCDLRGDLWDF
What is the function of this protein?
Binds to the promoter regions of genes involved in chlorophyll catabolic processes, such as NYC1, SGR1, SGR2 and PAO.
What are the official names of this protein?
NAC domain-containing protein 87, ANAC087.
What are the subcellular locations of this protein?
Nucleus.
Protein: SP2AB_CLOK5
Sequence: MYDNSMKIEFISKSQNESFARVSVAAFVSQLDPTLDELTDVKTAVSEAVTNSIIHGYENKEGIVKIEASIKGRELILIVEDNGIGIENIDMAMQPLYTSKPELERSGMGFTVMETFMDSLQVESEKNKGTRLIMKKVFNSLS
What is the function of this protein?
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F).  Phosphorylates SpoIIAA on a serine residue.  This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
What are the official names of this protein?
Anti-sigma F factor, Stage II sporulation protein AB.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: GP155_HUMAN
Sequence: MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFPALLECFGIVLCGYIAGRANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVLTLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMMLNPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVYVENFLDGLGNSFSGSALFYLGLTMVGKIKRLKKSAFVVLILLITAKLLVLPLLCREMVELLDKGDSVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIPVGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAGISLMCMNQTAQAGSYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNGELHCPSIEPIANTSTSEPVIPSFEKNNHCVSRCNSQSCILAQEEEQYLQSGDQQLTRHVLLCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIILPFKRRLEFLWNNKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQSPPAINANTLQQERYKEIEHSSPPSHSPKT
What are the official names of this protein?
Integral membrane protein GPR155, G-protein coupled receptor PGR22.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUVB_CAMFF
Sequence: MDRIVEIEKVSFESEYEVTLRPLTFEEYIGQEKIKSNLKVFIKAAKKRLESLDHVLFYGPPGLGKTTLAHIIANEMGANIKISSAPMIEKSGDLAAILTNLEEGDVLFIDEIHRLSPAIEEVLYSAMEDFRLDIIIGSGPAAQTIKIDIPKFTLIGATTRAGMISAPLRDRFGMQFRLQFYTDNELARIISIAASKLGKNSTKEASLEIAKRSRGTPRIALRLLKRIRDFAEVSDENSISKDRAKSSLDSLGVNDLGFDEMDLKYLDILVGSKRALGLSTIAAALSEDEGTVEDVIEPYLLSNGYIERTAKGRILSFKSYSVFGITPPMHITEEKQNKGLFNE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HISX_THEVB
Sequence: MLRIITQLTDLRAELRRICDRTDSGEMSEQQATVEAILRRVAKDGDRALIEYTAQFDHIDLTPETLRVKGDELDAAYQQVSKELLDAIRLAKQQIEAFHRQRVPKSWVQFGEDGVVLGKRYTAVDAAGLYVPGGRAAYPSTVLMNAIPAQVAGVQRIVMVTPPGQGKGINPAVLVAAQEAGIQEIYRVGGAQAIAALAYGTETIPRVDVITGPGNLYVMLAKKQVYGRVGIDSLAGPSEVLIIADEAAHPAQIAADLLAQAEHDPLAAAILLTPSLSLAKAVVTAVNEQLADHPRRVLTEKAIAHYGLIGIVETLEQAVELSNSFAPEHLELEVEDPWSLVEQVRHAGAIFLGYSTPEAVGDYLAGPNHTLPTSGAARYASALGVETFLKHSSIIQYTPAALRKQGGAVMTLAETEGLISHRDSVRLRLQP
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: RSMA_STAHJ
Sequence: MERKDIATPSRTKALLDQFGFNFKKSLGQNFLVDVNIIHKIIDASEIDDNTGIIEVGPGMGSLTEQLAKRAKKVMSFEIDQRLIPVLKETLAPYDNVTIINEDILKADIGKAVKTYLNDCDKIMVVANLPYYITTPILLNLMQQDIPIDGYVVMMQKEVGERLNAQVGTKAYGSLSIVTQYYTETSKVLTVPKSVFMPPPNVDSIVVKLMQRETPLVSVDDEETFFKLAKAAFAQRRKTINNNYQNFFKDGKKHKESILKWLEQTGIDPKRRGETLSIQDFARLYEEKKNFPELEN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2443_BACMK
Sequence: MKDLRYPIGQFTYVGTITEEIIDKWIQEIEDLPNELARAIKDLDQKQLDTPYRVGGWTVRQVVHHVVDSHMNSYIRFKLAMTEKNPTIKPYKEEKWAELPDSKLPVDVSLVMLDSLHKRWVNLLYSLEPADLEKTFNHPESGETKLAAAIGLYAWHGRHHTAHITSLRERLNW
What is the function of this protein?
Possible metal-dependent hydrolase.
What are the official names of this protein?
Putative metal-dependent hydrolase BcerKBAB4_2443.
What is the protein family that this protein belongs to?
Belongs to the metal hydrolase YfiT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_MESM1
Sequence: MARSAKKGFYVEASLMKKVVNAIESKSKKPIKTWSRRSTIFPEFVGFTFQVHNGRQFIDVYVTDDMVGHKLGEFSPTRTYTGHGSEKGKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: OCEL1_MOUSE
Sequence: MQIHAGPASRRGRRGPLARLSGPEATCNSRPAARGRQRAAAPRMPAPERPRSRRPQSQPGPGELCVKPRKIVFADELRPREPLHPEKHPRDLGPRLNPVPDYELKYPPVTNRRDRSRYAAVFQDQYGEFSELQREVGATQAKLQQLEALLLSLPPPRSQKEARMAAHVRREFEKKRVDPGFLDKQARCNYLKGKLRHLKAQIRKFDDQQDSNSEDSVYF
What are the official names of this protein?
Occludin/ELL domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the ELL/occludin family.
Protein: MNHA1_STAA8
Sequence: MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit A1, Mnh complex subunit A1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAPSD_BPFO1
Sequence: MLTNSEKSRFFLADLTGEVQSIPNTYGYISNLGLFRSAPITQTTFLMDLTDWDVSLLDAVDRDSRKAETSAPERVRQISFPMMYFKEVESITPDEIQGVRQPGTANELTTEAVVRAKKLMKIRTKFDITREFLFMQALKGKVVDARGTLYADLYKQFDVEKKTIYFDLDNPNADIDASIEELRMHMEDEAKTGTVINGEEIHVVVDRVFFSKLTKHPKIRDAYLAQQTPLAWQQITGSLRTGGADGVQAHMNTFYYGGVKFVQYNGKFKDKRGKVHTLVSIDSVADTVGVGHAFPNVAMLGEANNIFEVAYGPCPKMGYANTLGQELYVFEYEKDRDEGIDFEAHSYMLPYCTRPQLLVDVRADAKGG
What is the function of this protein?
Assembles to form an icosahedral capsid.  The assembly is primed by the interaction between capsid assembly protease and portal dodecamer, and major capsid proteins assemble cooperatively to form the procapsid with the help of capsid scaffolding protein.  Major capsid protein forms hexons and pentons of the icosahedron.  Viral genomic DNA is packaged into the procapsid through the portal vertex.  The packaging triggers a dramatic reconfiguration of the capsid shell.
What are the official names of this protein?
Major capsid protein, Gene product 58, gp58, Major head protein.
What is the protein family that this protein belongs to?
Belongs to the lambda phage major capsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Forms the capsid icosahedric shell.
Protein: TTHY_CHICK
Sequence: MAFHSTLLVFLAGLVFLSEAAPLVSHGSVDSKCPLMVKVLDAVRGSPAANVAVKVFKKAADGTWQDFATGKTTEFGEIHELTTEEQFVEGVYRVEFDTSSYWKGLGLSPFHEYADVVFTANDSGHRHYTIAALLSPFSYSTTAVVSDPQE
What is the function of this protein?
Thyroid hormone-binding protein.  Probably transports thyroxine from the bloodstream to the brain.
What are the official names of this protein?
Transthyretin, Prealbumin, TBPA.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DMBX1_CHICK
Sequence: MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKDCESSHSEGKTEPPVLETQSTIPDTEKTQSIPSEVSTDLNLTLSEQSASESAPEDQTDREEEFKSTLDEAKVDKSPGVDGKALNCKRASPKSESPISATVTPSSSSGLAQTHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEMGTPSAMPYLGMNVNMAPLSSLHCQSYYQSLSHAQQVWSSPILQASSSLPSLNSKTTSIENLRLRAKQHAASLGLDTLPN
What is the function of this protein?
Functions as a transcriptional repressor.  Required for brain development.
What are the official names of this protein?
Diencephalon/mesencephalon homeobox protein 1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FPG_MARMS
Sequence: MPELPEVETTLRGIEPKLVGRSLARVDIRQPKLRWLITPELSSEMVGEEITHLSRRGKYIGIHTSKGTLIVHLGMSGSLYFVPAETPPLFHDHVDFCFADDDVWLRYTDPRRFGAILWTTEDWHEHELIKHLGPEPLSDMFNADMLYVRAKGRKVPIKTFIMDSKVVVGVGNIYANEALFKAGIRPDRLAGNISKARLARLVECIKVVLAAAIKQGGTTLKDFVGGDGKPGYFKQELAVYGRANKACVICSKPLKEIRQAQRSTVFCINCQS
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SYUA_ATEGE
Sequence: MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTSVGGAVVTGVTAVAQKTVEGAGNIAAATGFVKKDHSGKSEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
What is the function of this protein?
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release (By similarity).  Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores (By similarity).  Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis (By similarity).  Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5 (By similarity).  This chaperone activity is important to sustain normal SNARE-complex assembly during aging (By similarity).  Also plays a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity (By similarity).
What are the official names of this protein?
Alpha-synuclein.
What is the protein family that this protein belongs to?
Belongs to the synuclein family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane. Nucleus. Synapse. Secreted. Cell projection, axon. Note=Membrane-bound in dopaminergic neurons (By similarity). Expressed and colocalized with SEPTIN4 in dopaminergic axon terminals, especially at the varicosities (By similarity).
Protein: OBG_MYCMM
Sequence: MPRFVDRVVIHTRAGSGGNGCASVHREKFKPLGGPDGGNGGRGGSVVFVVDPQVHTLLDFHFRPHVTAASGKQGMGSNRDGAAGADLEVKVPDGTVVLDDNGRLLADLVGAGTRFEAAAGGRGGLGNAALASRARKAPGFALLGEPGQARDLTLELKTVADVGLVGFPSAGKSSLVSVISAAKPKIADYPFTTLVPNLGVVAAGGHSFIVADVPGLIPGASQGRGLGLDFLRHIERCAVLVHVVDCATAEPGRDPISDIDALEAELAAYQPTLQGDAVLDDLAERPRAVVLNKIDVPEARELAEFVEDELAQRGWPVFLVSTVTRENLQPLIFGLWQMVSEYNAARPQAAPRRPVIRPVPVDDSGFDVQADGHGGFVVTGARPERWIGQTNFDNDEAVGYLADRLARLGVEEELLRLGAKPGCAVTIGEMTFDWEPQTPAGGHVAMSGRGTDVRLERSDRVGAAERKAARRQRRERDDD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_THERP
Sequence: MPVTIVLGGQWGDEGKGKITDALAATADIVVRPNGSTNAGHTVVTDEGVFKLHVIPSGILYPHCTCIIGAGVAVSPPDFLREIESLRERHPRLGQLYVSDRAHVIMPYHPLLDLYEERRRGAAGIGTTLRGNGPAFTDKIARRGIRIADLLPGSERSLRHKLETLLPEKNTLFIHLYGESPLDLDQLFEQARTWGEALAPYVIAAEVFVQDALDAGKSVIIEAAQGTMLDPDYGTYPYVTSSSPTAAGACQGAGVAPTQVDRIVGVFKAYTTRVGAGPFPTELTDETGQLIRERGREYGTTTGRPRRVGWFDAVAARYSARLNGMTEAALTKLDMLDPLPEVRICVGYRIDNQEVSAPPAQVERYAAVEPVYEVLPGWQCDTSQVTSFDDLPPEAQRYVARIEELIGVPITMIGVGPARRQILWRPAGALT
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_HAEIE
Sequence: MPRRRSVEARKILPDPKFGSELLAKFINVIMVDGKKSVAESIVYGALETLAQRTGKEPLEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALGMRWIVEAARKRGDKSMALRLANELSDASDNKGAAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ILVC_STAA9
Sequence: MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIKSKSIEK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YBEY_BACAA
Sequence: MSLLIDFIDETEEVKEEYVNLIREILGKAAQMEKIEDGAELSVTFVDNERIREINRDYRDKDQPTDVISFAMEEMGEGEMEIVGVEMPRMLGDLIISIPRAKEQAEEYGHSFDRELGFLALHGFLHLLGYDHMTEEDEKEMFGRQKEILEAFGLGR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCMB_MOOTH
Sequence: MPRFRDLSHNCRPSEAPRVMEPKNRDRTVDPAVLEMLVKSKDDKVITAFDRFVAQQPQCKIGYEGICCRFCMAGPCRIKATDGPGSRGICGASAWTIVARNVGLMILTGAAAHCEHGNHIAHALVEMAEGKAPDYSVKDEAKLKEVCRRVGIEVEGKSVLELAQEVGEKALEDFRRLKGEGEATWLMTTINEGRKEKFRTHNVVPFGIHASISELVNQAHMGMDNDPVNLVFSAIRVALADYTGEHIATDFSDILFGTPQPVVSEANMGVLDPDQVNFVLHGHNPLLSEIIVQAAREMEGEAKAAGAKGINLVGICCTGNEVLMRQGIPLVTSFASQELAICTGAIDAMCVDVQCIMPSISAVAECYHTRIITTADNAKIPGAYHIDYQTATAIESAKTAIRMAIEAFKERKESNRPVYIPQIKNRVVAGWSLEALTKLLATQNAQNPIRVLNQAILDGELAGVALICGCNNLKGFQDNSHLTVMKELLKNNVFVVATGCSAQAAGKLGLLDPANVETYCGDGLKGFLKRLGEGANIEIGLPPVFHMGSCVDNSRAVDLLMAMANDLGVDTPKVPFVASAPEAMSGKAAAIGTWWVSLGVPTHVGTMPPVEGSDLIYSILTQIASDVYGGYFIFEMDPQVAARKILDALEYRTWKLGVHKEVAERYETKLCQGY
What is the function of this protein?
The beta subunit (this protein) generates CO from CO(2), while the alpha subunit combines the CO with CoA and a methyl group to form acetyl-CoA.  The methyl group, which is incorporated into acetyl-CoA, is transferred to the alpha subunit by a corrinoid iron-sulfur protein.
What are the official names of this protein?
Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit beta, CODH subunit, CODH/ACS, Carbon monoxide dehydrogenase subunit.
Protein: FA53B_ORYLA
Sequence: MVIILKKTLEKKGADDVIASRANLGPFQAQTMSQGAALFSCGLMETSRWHDSCSIRQRPVGTSLESLWDVLPEVHSGSAQWDWDVGSASSTLTSLLQDLSLTESSSHSTAPPSKKQCRSLSCSDELGGCRSTWRPQGSRVWTTVEKRRCHSGGSVQRSSGGNLQLGFPAMQRSFSFSLPARSNAVEPPSFTQRLPYAFTSLTHSSSMPLASDPPAQPLSLSNEQICFPEPHGPSPSSSPDSTPELERRSGQGGLARSRSQPCELNEKKIGVKRRRPDDTHKQRPSLDLAKMTQKLHSFHSLSCPGITGEETCESEATPPPRSVQQRDAVDSPAHEHNLKDFQPQEGDFNGNKSSDPITEEVDWNCDDGTPETSNGKDTEPLWVGLCSMKRDVYQLGGELDIEQIERN
What is the function of this protein?
Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (ctnnb1) nuclear localization.
What are the official names of this protein?
Protein FAM53B, Protein simplet.
What is the protein family that this protein belongs to?
Belongs to the FAM53 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PFDA_PYRHO
Sequence: MAQNNKELEKLAYEYQVLQAQAQILAQNLELLNLAKAEVQTVRETLENLKKIEEEKPEILVPIGAGSFLKGVIVDKNNAIVSVGSGYAVERSIDEAISFLEKRLKEYDEAIKKTQGALAELEKRIGEVARKAQEVQQKQSMTSFKVKK
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.