PharMolix/UniProtQA huggingface dataset:
Protein: NDUB7_ARATH
Sequence: MEVPGSSKKMIATQEEMSAAKIALGSRDMCAHLLIPLNKCRQAEFYLPWKCEDERHVYEKCEYELVMERMLAMKKIREEEALAKQNKLQGNAAVPLIPKTANA
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB7 subunit family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
Protein: Y1687_LISMO
Sequence: MYLPKEKEIIQIKSYKHNGKLHRTWKKTVVLKSTENIIIGGNDHTLVVEADGRKWVTREPSICYFHSDYWFNVISMIREDGIYHYCNLGTPFAVDEQALKYIDYDLDIKVFPDGRFHLLDEGEYEQHRRQMKYPDSIDRILRHNVDVLSHWILDKKGPFSPDYIDIWYEKYKEYR
What are the official names of this protein?
UPF0374 protein lmo1687.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: MADS4_ORYSJ
Sequence: MGRGKIEIKRIENSTNRQVTFSKRRAGILKKAREIGVLCDAEVGVVIFSSAGKLSDYCTPKTTSVFPPLSRILEKYQTNSGKILWDEKHKSLSAEIDRVKKENDNMQIELRHMKGEDLNSLQPKELIAIEEALNNGQANLRDKMMDHWRMHKRNEKMLEDEHKMLAFRVHQQEVELSGGIRELELGYHHDDRDFAASMPFTFRVQPSHPNLQQEK
What is the function of this protein?
Probable transcription factor involved in the development of floral organs.  B-class protein required for normal development of lodicules and stamens (whorls 2 and 3).  May function as a heterodimer with MADS16.
What are the official names of this protein?
MADS-box transcription factor 4, OsMADS4.
What are the subcellular locations of this protein?
Nucleus.
Protein: MRAY_LEVBA
Sequence: MMNILLPLLGGFIITAAFMPALIRYFRARHEGQMIREEGPTWHEKKSGTPTMGGLLFIVAIAVMTLLTSWVLAPHHMLPTTWILIFILVLYGALGMWDDSIKLFHRQNEGLKAWQKMLGQIVGALILFWVYTHEQLPMALHVPGIGNWHMSGWYAVFVILWLVGFSNAVNLSDGLDGLVSGLASIAFAAYGIVAWQQAQINIAIFCFAVVGSLLGFLIFNHKPAKIFMGDTGSLALGGALAAVSILLHHELSLLWIGLIFVIETASVILQVASFKLTGKRIFLMSPIHHHFEMKGWSEWRIDLTFWGIGLVTALSGVWVILAK
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CID_DROME
Sequence: MPRHSRAKRAPRPSANNSKSPNDDDTAFRSPEPEDGTDYGLEFTTSQLTLQDNNRRSSTLRRDAGRRQPAARDSSTSGEEEDQENRYPTTRSPQTRRMTVQQESKTRAAGPVAAQNQTRRRKAANPMSRAKRMDREIRRLQHHPGTLIPKLPFSRLVREFIVKYSDDEPLRVTEGALLAMQESCEMYLTQRLADSYMLTKHRNRVTLEVRDMALMAYICDRGRQF
What is the function of this protein?
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore (PubMed:11483958, PubMed:16839185).  Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation (PubMed:24703848, PubMed:11483958, PubMed:16839185).  May serve as an epigenetic mark that propagates centromere identity through replication and cell division (PubMed:11483958, PubMed:16839185).
What are the official names of this protein?
Histone H3-like centromeric protein cid, CENP-A homolog, Centromere identifier protein.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres. Co-expressed with yemalpha.
Protein: OR7A5_HUMAN
Sequence: MEPGNDTQISEFLLLGFSQEPGLQPFLFGLFLSMYLVTVLGNLLIILATISDSHLHTPMYFFLSNLSFADICVTSTTIPKMLMNIQTQNKVITYIACLMQMYFFILFAGFENFLLSVMAYDRFVAICHPLHYMVIMNPHLCGLLVLASWTMSALYSLLQILMVVRLSFCTALEIPHFFCELNQVIQLACSDSFLNHMVIYFTVALLGGGPLTGILYSYSKIISSIHAISSAQGKYKAFSTCASHLSVVSLFYGAILGVYLSSAATRNSHSSATASVMYTVVTPMLNPFIYSLRNKDIKRALGIHLLWGTMKGQFFKKCP
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 7A5, Olfactory receptor OR19-17, Olfactory receptor TPCR92.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ULAG_ESCF3
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKAGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPAEQKAAGVLPDGMDERAVNYLFKTPGGTLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMAEALNTKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMPF_CHLMU
Sequence: MTRRILPLSLVFIPLSCISASETDTLKLPNLTFGGREIEFIVTPPSSIAAQYITYANVSNYRGNFTISSCTQDQWFSRGLSTTNSSGAFVESMTSFTAIDNADLFFCNNYCTHQGGGGAINATGLISFKNNQNILFYNNTTIGTQFTGVALRTERNRGGALYGSSIELINNHSLNFINNTSGDMGGAVSTIQNLVIKNTSGIVAFENNHTTDHIPNTFATILARGGAVGCQGACEISHNTGPVVFNSNYGGYGGAISTGGQCIFRDNKDKLIFINNSALGWHNTSAQGNGAVISAGGEFGLLNNKGPIYFENNNASYIAGAISCNNLNFQENGPIYFLNNSALYGGAFHLFASPAANYIHTGSGDIIFNNNTELSTTGMSAGLRKLFYIPGTTNNNPITLSLGAKKDTRIYFYDLFQWGGLKKANTPPENSPHTVTINPSDEFSGAVVFSYKNISSDLQAHMIASKTHNQIKDSPTTLKFGTMSIENGAEFEFFNGPLTQESTSLLALGQDSILTVGKDASLTITHLGIILPGLLNDQGTTAPRIRVNPQDMTQNTNSNQAPVSTENVATQKIFFSGLVSLVDENYESVYDSCDLSRGKANQPILHIETTNDAQLSNDWKNTLNTSLYSLPHYGYQGLWTSNWMTTTRTVSLTNSTETQTANNSIQEQKNTSETFDSNSTTTAKIPSIRASTGGTTPLATTDVTVTRHSLVVSWTPIGYIADPARRGDLIANNLVSSGRNTTLYLRSLLPDDSWFALQGSAATLFTKQQKRLDYHGYSSASKGYAISSQASGAHGHKFLFSFSQSSDTMKEKRTNNKISSRYYLSALCFEQPMFDRIALIGAAAYNYGTHKTYNFYGTKKFSKGNFHSTTLGGSLRCELRDSMPFQSIMLTPFIQALISRTEPASIQEQGDLARLFSLKQPHTAVVSPIGIKGVYSSNKWPTVSCEMEVAYQPTLYWKRPILNTVLIKNNGSWETTNTPLAKHSFYGRGSSSLKFSYLKLFANYQAQVATSTVSHYMNAGGALVF
What are the official names of this protein?
Probable outer membrane protein PmpF, Polymorphic membrane protein F.
What is the protein family that this protein belongs to?
Belongs to the PMP outer membrane protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell outer membrane; Peripheral membrane protein; Extracellular side.
Protein: DEF_BIFAA
Sequence: MFGHNSKVDLELNREVEKLIKTGGKEKIMPIVQAGEPVLRQQTIAYDGQLSRKTLDKLIDTMRTTMLEAPGVGLAATQIGLGLALAVVEDHVCEGDDGDPREAAEFPFHAIINPSYEPIGTETRSFYEGCLSFDGYQAVRKRWLDITARWQDEDGNKHEEHLHGWPARIFQHETDHLSGELYIDQAEIRSLTTNENLEDFWCEDPVPTEAAAELGFEL
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: THIG_DESPS
Sequence: MADMLTIAGKTFSSRLFIGTGKFASPEIMRDVLQACKSQMVTVALRRVNLADPEDDIMSQIDTGETNFLPNTSGARNAEEAIRLAELARAGSGTNWVKIEVVPDPRTLLPDPIETLKATEELVKRGFIVLPYMNVDPILALRLQDVGAAAVMPLAAPIGTNLGITNRLQLEMIIEQARVPVVIDAGLGAPSHAALAMELGADAVLVNTAIAVADKPVAMAEAFAMATIAGRAAYLAGLGSQCPVASASSPVSGNITVDLDFLD
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBID_YERPE
Sequence: MISMKYRDLRDFLSLLEQRGELKRISQPIDPYLEMTEIADRTLRAGGPALLFENPKGYSMPVLCNLFGTAKRVAMGMGQEDVSALRDVGKLLAFLKEPDPPKGFRDLFDKLPKFKQVLNMPTKRLNSAPCQEQVWQGEDVDLSRIPVMHCWPEDAAPLVSWGLTITRGPHKERQNLGIYRQQVLGKNKLIMRWLSHRGGALDYQEWCEAHPGERFPVAVALGADPATILAAVTPVPDTLSEYAFAGLLRGHKTEVVKCLSNDLEVPASAEIVLEGYIEQGDMAPEGPYGDHTGYYNEIDNFPVFTVTHITQRQDAIYHSTYTGRPPDEPAVMGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGIWSFLRQFMYTKFVIVCDDDINARDWNDVIWAITTRMDPSRDTVLIENTPIDYLDFASPVSGLGSKMGLDATNKWPAETPREWGRPIKMDEDVRARIDALWDELAIFSDKDAKR
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VDAC_DORPE
Sequence: VPPVYADLGKGARDLFSKGYNYGFSKL
What is the function of this protein?
Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules.
What are the official names of this protein?
Voltage-dependent anion-selective channel protein, VDAC, Outer mitochondrial membrane protein porin.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: RL32_PSYIN
Sequence: MAVQKSRKTRSKRGMRRSHDALTAPAQLSVDATSGETHRRHHMTADGFYRGKKVIEL
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SCP_PSHV1
Sequence: MSTSSRQQSPAGGDGSTGGGSAAHCSGHAPVNALVEFLRTAPRTHTPEQLQAIARSSINDLSEALRALRTDLPKGDPVRGFLRANTTLALSLLNHAPRLREQLNIQPVAARLTGPQGFWSFGIRQRNRPQILRPPQLSRKK
What is the function of this protein?
Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument.  Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly.
What are the official names of this protein?
Small capsomere-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae small capsomere-interacting protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ATPF_SACOF
Sequence: MKNVTHSFVFLAHWPFAGSFGLNTDILATNLINLTVVVGVLIFFGKGVLKDLLDNRKQRILSTIRNSEELRRGTLEQLEKARIRLQKVELEADEYRMNGYSEIEREKENLINATSISLEQLEKSKNETLYFEKQRAMNQVRQRVFQQAVQGALGTLNSCLNTELHFRTIRANIGILGAIEWKR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ARR1_ONCMY
Sequence: MGDKAGTRVFKKSSPNCKVTVYLGKRDFVDHLDQVDPVDGVILVDPEYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLYISTFQAFPPIAEERKANSRLQERLLKKLGQQAHPFYFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSIEEKIHKRNSVRLVIRKVQYAPEKPGPQPMVETTRSFLMSDRSLHLEASLDKELYYHGEPISVNVHVTNNSTKTVKRLKISVRQYADICLFSTAQYKCPVAQVEADDQVSSSSTFCKVYTLTPTLDKNREKRGLALDGKLKHEDTNLASSTIVKDVTNKEVLGILVSYRVKVKLVISRGGDVSVELPFVLMHPKPTELPISRPQSAVPDSDPPIDTNLIEFETNSFSQDDDFVFEDFARLRLKGMADDKDDDC
What are the official names of this protein?
Arrestin red cell isoform 1, TrCarr 1.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_XYLFA
Sequence: MLYLASRSLCRRQLLQRLDIPFQVIDLEIPEVRREDELPQDYVRRVAQEKAQVGLARVRDAFAPKVLGADTEVVLDGRVFGKPADLVEAAAMLAALSGRTHQVMTAVSLVAAGGVAAQVLVVSEVSFALLSQGQIARYVDSGEPMGKAGAYAIQGRGECFVSRLVGSYSGVMGLPLQQTAQLLTTFEES
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBL_HALTV
Sequence: MTRTVIAQGTFDILHPGHVHYLEEAAAMGDELLVIVARKSNVDHKEKPICPAAQRRDVVAALEAVDDAIVGHEEDIFAPIEAIDPDVIALGHDQHHDDDAIEAELERRGIDCTVERASAREPEREDEILSTRLIIDRILERRG
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: MALT_AEDAE
Sequence: MKIFVPLLSFLLAGLTTGLDWWEHGNFYQVYPRSFKDSDGDGIGDLDGVTEKLKYLKDIGMDGVWLSPIFSSPMADFGYDISNFREIQTEYGDLDAFQRLSDKCKQLGLHLILDFVPNHTSDQHEYFKKSVQKDETYKDFYVWHPGVHGPNNTKVPPSNWISVFRGSSWEWNEERQEFYLHQFLKEQPDLNYRNPAVVEEMKNVLRYWLDRGVSGFRIDAVPYLFESDIIDGRYRNEPESRTTDDPENPAYLVHTQTMDQPETYDMIYQWRAVLDEYSKTDNRTRIMMTEGYTSLPKIIEFFGNATANGAQIPFNFEVISNVKKNSTGADFATYVKRWLDAKPANRRSNWVLGNHDNNRLGSRLGENKIDLYNIALQTLPDIAVTYYGEEIGMLDQWIPWNETVDPAACRSDEASYSAYSRDPARTPMQWDSGKNAGFSKAAKTWLPVADNYKTLNVKIQDRARKSHLKIFKKLTKYRKRQILTEGDIDIKVSGENLLVYKRKVDKVGYVVVALNFGTEPVALGLSSLFDRADQRMQVVVSSNRVSTPDNVWVDVDNYVLIGESGIVLQYLWGKNPIVS
What is the function of this protein?
Assists the mosquito in its sugar-feeding capabilities (Potential).  Glucosidase (By similarity).
What are the official names of this protein?
Probable maltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: RL14_SHEPW
Sequence: MIQMQSTLEVACNSGARRVQCIKVLGGSHRRYAGIGDVIKVSVKEAIPRGKAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLNANLAPIGTRIFGPVTRELRTEQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GLMU_CORA7
Sequence: MAEVTNCAAIVLAAGAGTRMKSSTQKTLHEIGGRSLLGHALHAAAGLNPEHLVVVVGHQRDQVSPAVDAISEELDCAVSQAVQEEQNGTGHAVQCGLSALPEFDGTVIVTNGDVPLLRPETLRQLHEAHTGEANAVTVLSMTLEDPTGYGRVLRADDGSVTAIVEQKDASEEQRKVREVNSGVFAFDGAVLRDALTKLNSDNAQGELYITDVLEIAREAGHRVGAHVAADPEELSGVNDRVQLAAAGRLLNRRMVEEAMRGGTTIVDPDTTWIGVNVTIGQDVVIHPNTQLWGATTIADGAEVGPDTTLTNIQVGAGASVVRTHGFDSVIGSNAQIGPFTYIRPGVIVGEEGKLGGFVEAKKTQIGRGTKVPHLTYIGDATVGDYSNIGASSVFVNYDGVNKHHTTIGSHVRTGSDTMFIAPVTVGDGAYSGAGTVIKDDVPPGALAVSGGKQRNIEGWVQKKRPGTPAAEAAGKAQDAKANDQTTN
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_ECOL5
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCNNA_CAVPO
Sequence: MLMRLLPLPSLTDGRPLGCCCTCQGSMKGDELKAQGPLPPQPLQGPLKGDKCEQPGLGPEPTAPQQHTEEEEALIEFHRSYRELFQFFCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFGEYFSYPVSLNINLNSDKLVFPAVTVCTLNPYRYKEIKEQLRELDRITQQTLFDLYNYNASSTLLAGARSRRSLADTLPYPLQRIPVQPEPRRARSSDPSSVRDNNPRVDRRDWRVGFQLCNQNKSDCFYQTSSSGVDGVREWYRFHYINILAQVADTSPRWEEETLGNFIFACRFNQAPCTQENYSHFHHPIYGNCYTFNNKNDSSLWMASMPGINNGLSLTLRTEQNDYIPLLSTVTGARVTVHGQDEPAFMDDGGFNLRPGVETSISMRKEALDRLGGSYGDCTQDGSDVPVQNLYPSKYTQQVCIHSCFQENMIKQCGCAYIFYPKPKGVEFCDYTNHSAWGYCYYKLQGAFSSDSLGCFNKCRKPCNVTIYKLSAGYSRWPSAASQDWIFQMLSLQNNYTISNKRNGVAKLNIYFKELNYRTNSESPSVTMVTLLSNLGSQWSLWFGSSVLSVVEMAEFMFDLLVITLLMLLRRFRSRYWSPGRGARAAREVACTPPPSLPSRFCAHSAFPTLTAPPPAYATLSACPPLQGLAGASSAACAPREP
What is the function of this protein?
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride.  Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells.  Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.  Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands.  Also plays a role in taste perception.
What are the official names of this protein?
Amiloride-sensitive sodium channel subunit alpha, Alpha-NaCH, Epithelial Na(+) channel subunit alpha, Alpha-ENaC, Nonvoltage-gated sodium channel 1 subunit alpha, SCNEA.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1A subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell projection, cilium. Cytoplasmic granule. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum. Note=In the oviduct and bronchus, located on cilia in multi-ciliated cells. In endometrial non- ciliated epithelial cells, restricted to apical surfaces. In epidermis, located nearly uniformly in the cytoplasm in a granular distribution. In sebaceous glands, observed only in the cytoplasmic space in between the lipid vesicles. In eccrine sweat glands, mainly located at the apical surface of the cells facing the lumen. In skin, in arrector pili muscle cells and in adipocytes, located in the cytoplasm and colocalized with actin fibers.
Protein: RTD1A_MACMU
Sequence: MRTFALLTAMLLLVALHAQAEARQARADEAAAQQQPGTDDQGMAHSFTWPENAALPLSESAKGLRCICTRGFCRLL
What is the function of this protein?
RTD-1 and RTD-3 have similar antimicrobial activities against the Gram-positive bacteria S. aureus 502A and L. monocytogenes, the Gram-negative bacteria S. typhimurium and E. coli ML35, and the fungi C. albicans 16820 and C. neoformans 271A.
What are the official names of this protein?
Rhesus theta defensin-1/3 subunit A, RTD-1 subunit A, RTD-1a, Demidefensin-2, RTD-3.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family. Theta subfamily.
Protein: AV2_TLCVA
Sequence: MWDPLVHEFPETVHGFRCMLANKYLLAVESKYAPDTLGYELIRDCIGVVRSRNYEQATSRYRDIYTRLQGATEAELQQSVQERCCCPHCPRHKKADMGESAHVQKAHDVQAVQKP
What is the function of this protein?
Through its interaction with host SGS3, acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Protein V2.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae protein AV2/V2 family.
What are the subcellular locations of this protein?
Host cytoplasm, host perinuclear region. Note=Accumulates in inclusion bodies in the cell periphery. May interact with the ER network from the perinuclear region out to the cell periphery (By similarity).
Protein: PYRF_NITEU
Sequence: MNDPRIIVALDFPDQCTALNFAAGLDSTLCRVKVGKELFTLAGPQLVEKLMKLGFDVFLDLKFHDIPNTVAAACSAASSLGVWMVNVHALGGSKMLLAARQALDGKRTRLIAVTLLTSLNQNDLSELGIADTPETMVQRLALLAQRCGLDGVVCSALEAVSLREVTGEDFCLVTPGIRSFGDGNDDQARIATPAMAIRSGASYLVIGRPITRSPDPLGALRRFNDEVASVL
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: DDL_STRT2
Sequence: MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYNAFEVKTYFITQSGDFIKTQEFIETPGDDEKLMTNDTVEASQAIKPSDIYEEDAVVFPVLHGPMGEDGSIQGFLETLKLPYVGTNVLSSSVAMDKIMTKRILEVAGVPQVAYTVYIEGEDLEAAVAETLEKLTFPVFVKPANMGSSVGISKAENESELRSAIDLALKYDSRILIEQGVVAREIEVGILGNTTVKTTDPGEVVKDVAFYDYQAKYIDNKITMDIPARVPVEVMTQMRAYAAKAFRALGGCGLARCDFFLTEDGAIYLNELNTMPGFTQWSMYPLLWENMGLSYSDLIKELVVLGQEMFDKRESHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2271_SHEPW
Sequence: MAIQSKYSNTQVESLITELLAVLEKHQSPTDLSLMALGNCVTHLLQNKVPAEAREVVTEQFAKALSQSVKNS
What are the official names of this protein?
UPF0352 protein swp_2271.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: CASP5_HUMAN
Sequence: MAEDSGKKKRRKNFEAMFKGILQSGLDNFVINHMLKNNVAGQTSIQTLVPNTDQKSTSVKKDNHKKKTVKMLEYLGKDVLHGVFNYLAKHDVLTLKEEEKKKYYDTKIEDKALILVDSLRKNRVAHQMFTQTLLNMDQKITSVKPLLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
What is the function of this protein?
Thiol protease that acts as a mediator of programmed cell death (PubMed:29898893, PubMed:28314590).  Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD): cleavage releases the N-terminal gasdermin moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis (PubMed:29898893).  During non-canonical inflammasome activation, cuts CGAS and may play a role in the regulation of antiviral innate immune activation (PubMed:28314590).
What are the official names of this protein?
Caspase-5, CASP-5, ICE(rel)-III, Protease ICH-3, Protease TY.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.