PharMolix/UniProtQA huggingface dataset:
Protein: CINAL_SHEPW
Sequence: MKLEMICTGEEVLAGQIVDTNAAWFANMLMEHGVECQRRITVGDRLEDLVAVFQERSTEADVIVVNGGLGPTSDDLSSEAMALAKGEPLVENKIWRDRLDDWFTRNGRVMAESNLKQALIPESAIMIDNPVGTACGFAVKLNRAWLFFTPGVPFEFKQMIKEQFIPFINERFEIAGDVALRKYLTLGQGESSLADALETIVLPEGITIGYRSSMPHIEIKLFARGKAAISEMDKIEAQIRFLLGTAIVANNKKSLAEEIHALLIDSGKTLSAAESCTGGMIASQLISHAGSSAYLDQGLVTYSNESKVKVLGVKPETLDDHGAVSIATVEEMASGARAILNSDYALATSGIAGPTGGTEDKPVGTVAIALATKSGVYSQMIKLPRRSRDLVRSLSTAVAFDMLRRELLDEAVIVDYGSIKRFQK
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: NRC2_NEUCR
Sequence: MPSTKNANGEGHFPSRIKQFFRINSGSKDHKDRDAHTTSSSHGGAPRADAKTPSGFRQSRFFSVGRLRSTTVVSEGNPLDESMSPTAHANPYFAHQGQPGLRHHNDGSVPPSPPDTPSLKVDGPEGSQQPTAATKEELARKLRRVASAPNAQGLFSKGQGNGDRPATAELSKEPLEESKDSNTVGFAEQKPNNDSSTSLAAPDADGLGALPPPIRQSPLAFRRTYSSNSIKVRNVEVGPQSFDKIKLIGKGDVGKVYLVKEKKSGRLYAMKVLSKKEMIKRNKIKRALAEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCSGGEFFRALQTRPGKCIPEDDARFYAAEVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKQSDPGGKPTMIIGKNGTSTSSLPTIDTKSCIANFRTNSFVGTEEYIAPEVIKGSGHTSAVDWWTLGILIYEMLYGTTPFKGKNRNATFANILREDIPFPDHAGAPQISNLCKSLIRKLLIKDENRRLGARAGASDIKTHPFFRTTQWALIRHMKPPIVPNQGRGIDTLNFRNVKESESVDISGSRQMGLKGEPLESGMVTPGENAVDPFEEFNSVTLHHDGDEEYHSDAYEKR
What is the function of this protein?
Controls entry of the cell into the asexual developmental program.  Required to repress entry into the conidiation program.
What are the official names of this protein?
Serine/threonine-protein kinase nrc-2, Non-repressible conidiation protein 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. KIN82 subfamily.
Protein: RN145_MOUSE
Sequence: MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLNNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFVTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFVVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPVATQEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLPGLGTEAAPQPPAGAEQNIVLQEGPEPPDHESPPGTGTQEGSGDSSEHINRGSASQEGAADAGEGPQIPEGEVCPVESA
What is the function of this protein?
E3 ubiquitin ligase that catalyzes the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate.  In response to bacterial infection, negatively regulates the phagocyte oxidative burst by controlling the turnover of the NADPH oxidase complex subunits.  Promotes monoubiquitination of CYBA and 'Lys-48'-linked polyubiquitination and degradation of CYBB NADPH oxidase catalytic subunits, both essential for the generation of antimicrobial reactive oxygen species (PubMed:26194095).  Involved in the maintenance of cholesterol homeostasis.  In response to high sterol concentrations ubiquitinates HMGCR, a rate-limiting enzyme in cholesterol biosynthesis, and targets it for degradation.  The interaction with INSIG1 is required for this function (PubMed:29374057).  In addition, triggers ubiquitination of SCAP, likely inhibiting its transport to the Golgi apparatus and the subsequent processing/maturation of SREBPF2, ultimately down-regulating cholesterol biosynthesis (PubMed:29068315).
What are the official names of this protein?
RING finger protein 145.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LEUC_PSEAE
Sequence: MAGKTLYDKLWDMHLVKQRDDGSALIYIDRHILHEVTSPQAFEGLRLAGRKPWRIDANIATPDHNVPTTRTERKGGIAAIADEVSRLQVQTLDENCDDFGITEFKMNDVRQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLVAKKMKNMLVKVEGRLPAGVTAKDIVLAVIGRIGTAGGNGHAIEFAGSAIRDLSIEGRMTICNMSIEAGARVGLVAVDQKTIDYVKGRPFAPSAEQWDQAVACWQGLVSDADARFDTVVELDAAQIKPQVSWGTSPEMVLAVDQNVPDPARESDPIKRGSIERALKYMGLRPNQAITDIQLDRVFIGSCTNSRIEDLRAAAEVARGRKVAATIKQALVVPGSGLVKEQAEKEGLDRIFIEAGFEWREPGCSMCLAMNPDRLESGEHCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVNGRFIDVRELLA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MYCP5_MYCTU
Sequence: MQRFGTGSSRSWCGRAGTATIAAVLLASGALTGLPPAYAISPPTIDPGALPPDGPPGPLAPMKQNAYCTEVGVLPGTDFQLQPKYMEMLNLNEAWQFGRGDGVKVAVIDTGVTPHPRLPRLIPGGDYVMAGGDGLSDCDAHGTLVASMIAAVPANGAVPLPSVPRRPVTIPTTETPPPPQTVTLSPVPPQTVTVIPAPPPEEGVPPGAPVPGPEPPPAPGPQPPAVDRGGGTVTVPSYSGGRKIAPIDNPRNPHPSAPSPALGPPPDAFSGIAPGVEIISIRQSSQAFGLKDPYTGDEDPQTAQKIDNVETMARAIVHAANMGASVINISDVMCMSARNVIDQRALGAAVHYAAVDKDAVIVAAAGDGSKKDCKQNPIFDPLQPDDPRAWNAVTTVVTPSWFHDYVLTVGAVDANGQPLSKMSIAGPWVSISAPGTDVVGLSPRDDGLINAIDGPDNSLLVPAGTSFSAAIVSGVAALVRAKFPELSAYQIINRLIHTARPPARGVDNQVGYGVVDPVAALTWDVPKGPAEPPKQLSAPLVVPQPPAPRDMVPIWVAAGGLAGALLIGGAVFGTATLMRRSRKQQ
What are the official names of this protein?
Mycosin-5, MycP5 protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL30_THEVO
Sequence: MLAVIRIRGRTGIKQDIEDTAHLLRLNRINHLVLLQEDAVTKGMLQKVKDYVTWGEIDVDTLEVLLKNRCLFKGRRKLTEEELKDVTGFGSYRDLAKALVDGKIKFSEINDVVPVIRLNPPYKGYEAIKTSYRNGGSAGYRGKDINNLIRRMIIPGVDLNGQREN
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: C3HPD_STAND
Sequence: MKITGIKAWKVGLPLKEGRYNWSNGNFVEVFDSTVVAVETDAGITGYAECCPLGSAYLPAYAHGVRAGLEEIGPKVIGLDPTDLNVLNRHMDSVLRGHPYVKAPIDIACWDILGKVSGLPVYKLLGGAAQEKVALYRAISQEAPEAMARKIAGYKAEGYTKFQLKVGGDADQDIDRIRVTREILDATDTLVADANTGWTRAEAARIAAEVGDLDVYIEQPCPTYEECLSVRARTARPFVLDEVIDGVGTLMKALADDAMDIINLKISKVGGLTKARLMRDICVASGTPMTIEDTWGGDIVTATIAHLARSTPEEFSFSATDFNSYGTVDIAKGAPKRVNGFMTASDAPGLGIEPIFEVLGEPVVVIG
What is the function of this protein?
Catalyzes the dehydration of cis-3-hydroxy-L-proline (c3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C).  May be involved in a degradation pathway that converts c3LHyp to L-proline, which would allow S. novella to grow on c3LHyp as a sole carbon source.
What are the official names of this protein?
Cis-3-hydroxy-L-proline dehydratase, c3LHyp dehydratase, c3LHypD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: OPY2_YEAST
Sequence: MSSSSKASASSSLSSTATSSTSATRGSDGCVVCDSTASCPVCASGEYCVMTSLTCDKCPSTYCAKQSDSQLSSLSSSSSSSSSSNSNEKTSLIVGFTVGIVGGAMLIALVALYFINKRYWKPKRQKNKALKLEEASQSYGNEEEYFDDEDDDDEDDEDDGGMRKDESHTLFNTSLVPPTLNVPGNRSSASTTRTRASNILPIAYIPGVTSGLSTDKLQSKLRSSSKRQNAAGDIRSHITLGSSILDGLDDEDDEHNQVLNKDADDNLITAIRAKPKLVQIAEEESDKEIQDLDVIEEQTEADDLSHMAKSEASHGNNDEDDDEEGSFILDLEIPESIRESTQGSRTESPFEDKFEIHDER
What is the function of this protein?
Component of the high-osmolarity glycerol (HOG) pathway involved in mating response and osmotolerance.  May act as a membrane anchor for the STE50/STE11 complex.
What are the official names of this protein?
Protein OPY2, Overproduction-induced pheromone-resistant protein 2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Vacuole membrane; Single-pass membrane protein.
Protein: CML11_ORYSJ
Sequence: MSEPATTTPTPTPAGDHDAAATACKPAETTTALITCRSSSCSAQQQQQQQQQQEEPLGDDQLGELREIFRSFDRNGDGSLTQLELGSLLRSLGLKPSTDELDSLIQRADTNSNGLIEFSEFVALVAPELLYDRAPYSEDQIRRLFNIFDRDGNGFITAAELAHSMAKLGHALTVKELTGMIKEADTDGDGRISFQEFSRAITAAAFDNIFS
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML11, Calmodulin-like protein 11.
Protein: Y505_MYCPN
Sequence: MRKKRLLSRISFSSLFLLCGTVLSAYTGIQADLRNLIKETTKKDIDVYKAIKTTEGKKNIITSLKKSYEVNPKDTTKLLLDAWKQSFEKGELGIPDLDFEDVIYPKTSEPFKFERKVDHFQMTYQSFKDLSIEAKLSYNFNWFGDYSLGGFTAKKGDKHYFDLFLKIKSNSDPKKQFTTEKFLTKEEKNKVNGKEITRNLEWIEFSASLSWLIKGKDDVSQKSVKQFLSSYANNTSGYSRDINLFIYLEYLIK
What are the official names of this protein?
Uncharacterized protein MPN_505.
What is the protein family that this protein belongs to?
Belongs to the MG439/MG440 family.
Protein: RNF4_MOUSE
Sequence: MSTRNPQRKRRGGTVNSRQTQKRTRETTSTPEVSLETEPIELVETVGDEIVDLTCESLEPVVVDLTHNDSVVIVEERRRPRRNGRRLRQDHADSCVVSSDDEELSRDKDVYVTTHTPRSTKDDGATGPRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYI
What is the function of this protein?
E3 ubiquitin-protein ligase which binds polysumoylated chains covalently attached to proteins and mediates 'Lys-6'-, 'Lys-11'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination of those substrates and their subsequent targeting to the proteasome for degradation (PubMed:20681948).  Regulates the degradation of several proteins including PML and the transcriptional activator PEA3 (By similarity).  Involved in chromosome alignment and spindle assembly, it regulates the kinetochore CENPH-CENPI-CENPK complex by targeting polysumoylated CENPI to proteasomal degradation (By similarity).  Regulates the cellular responses to hypoxia and heat shock through degradation of respectively EPAS1 and PARP1 (By similarity).  Alternatively, it may also bind DNA/nucleosomes and have a more direct role in the regulation of transcription for instance enhancing basal transcription and steroid receptor-mediated transcriptional activation (By similarity).  Catalyzes ubiquitination of sumoylated PARP1 in response to PARP1 trapping to chromatin, leading to PARP1 removal from chromatin by VCP/p97 (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF4, RING finger protein 4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Nucleus, nucleoplasm.
Protein: M12_STRPY
Sequence: MAKNTTNRHYSLRKLKTGTASVAVALTVVGAGLVAGQTVRADHSDLVAEKQRLEDLGQKFERLKQRSELYLQQYYDNKSNGYKGDWYVQQLKMLNRDLEQAYNELSGEAHKDALGKLGIDNADLKAKITELEKSVEEKNDVLSQIKKELEEAEKDIQFGREVHAADLLRHKQEIAEKENVISKLNGELQPLKQKVDETDRNLQQEKQKVLSLEQQLAVTKENAKKDFELAALGHQLADKEYNAKIAELESKLADAKKDFELAALGHQHAHNEYQAKLAEKDGQIKQLEEQKQILDASRKGTARDLEAVRQAKKATEAELNNLKAELAKVTEQKQILDASRKGTARDLEAVRKSKKQQVEAALKQLEEQNKISEASRKGLRRDLDTSREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKDLEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMAAA
What is the function of this protein?
This protein is one of the different antigenic serotypes of protein M.  Protein M is closely associated with virulence of the bacterium and can render the organism resistant to phagocytosis.
What are the official names of this protein?
M protein, serotype 12.
What is the protein family that this protein belongs to?
Belongs to the M protein family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: SECY_CYACA
Sequence: MRPENNLRLRLFQTMKFIALERLGLFVPIPGIDQKLFSSDYSNNAISNLLNVFDNNQAPKLSVFALGIIPYINATITIQILSSAFPALKKLQSEEGEIGKKKLNKITKYLSFCFAFIESLAIVLRLQKYAFDWNLYFIVQTTLILISGAMLVMWLADNISYKGIGTGASVIIFVNIASAFAKFLLNQLFVHSIKFLDFASYFALIVFSIACIVFVQEAIRKVPIISAKQLDSTSFYSNDYFLPLRINQGGVMPIILASSLLALVDYVIRYGLSTLQAVYFINDILPFKILFLLLYSAFIIFFNYLYCSLVLNCFELSNNLKKASVVIPSIRPGKMTEKFFKDTLDNLTLFGSGFLAFIVLAPNFLEFVFHIRVFKGLAVSSLLIVVGVAIDLIKQSKTYVIAKNYENMVH
What is the function of this protein?
The central subunit of the protein translocation channel SecYE.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KDSA_SALAR
Sequence: MKQKVVNIGDIKVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKVITDVHEASQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFHEGGNDKVILCDRGANFGYDNLVVDMLGFGVMKKVSGNCPVIFDVTHALQCRDPFGAASGGRRGQVTELARAGMAVGLAGLFLESHPDPANAKCDGPSALPLAKLEQFLTQIKAIDDLVKSFDELDTEN
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLYF_ASPFU
Sequence: MWSSIAAFPVLVPVALACLGYEGGVPTPTAHHSNSAVIEVAAGQVFDAGWAKYDRGSGACKGQSEGDWKDAVFYLHSGATLKNVIIGANQAEGVHCDGPCTLQFVWFEDVCEDAITIKNDKAGQETWIIGGGAYHASDKIVQHNGCGTVNIINFYAEDYGKVPRSCGNCDKQCKRNVYVEGTTARNGGEVVGINLNYGDTATLKNVCADSAHPCVFYDGCAGDCEPKKVGYCSG
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester (By similarity).
What are the official names of this protein?
Probable pectate lyase F.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: COBS_LEPCP
Sequence: MAALIHEARLFFIALQFFTRVPVPAWVGYTPEWMHASARHYPLVGAWVGGVAALVLWLAAQVWPLSVAVGLSMAATVWLTGGFHEDGLADTCDGLGGSVSRERALTIMKDSRLGSYGALGLVGVLGLKAVALYELTDFDGVQALIALVWAHAVSRAVPVALLRLLPYAGDAEHAKAKPMAQQVSDAGLAAALGWAALACAAAWGLGASAFTLACAALGVIALAAFCVRWYRQRLGGYTGDTLGAAQQLCELAAYLGWLAGVWFE
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FRS5_ARATH
Sequence: MMDNEVLDFDIGVGVSSGGDVDDDAIDIEHHALDDDDMLDSPIMPCGNGLVGNSGNYFPNQEEEACDLLDLEPYDGLEFESEEAAKAFYNSYARRIGFSTRVSSSRRSRRDGAIIQRQFVCAKEGFRNMNEKRTKDREIKRPRTITRVGCKASLSVKMQDSGKWLVSGFVKDHNHELVPPDQVHCLRSHRQISGPAKTLIDTLQAAGMGPRRIMSALIKEYGGISKVGFTEVDCRNYMRNNRQKSIEGEIQLLLDYLRQMNADNPNFFYSVQGSEDQSVGNVFWADPKAIMDFTHFGDTVTFDTTYRSNRYRLPFAPFTGVNHHGQPILFGCAFIINETEASFVWLFNTWLAAMSAHPPVSITTDHDAVIRAAIMHVFPGARHRFCKWHILKKCQEKLSHVFLKHPSFESDFHKCVNLTESVEDFERCWFSLLDKYELRDHEWLQAIYSDRRQWVPVYLRDTFFADMSLTHRSDSINSYFDGYINASTNLSQFFKLYEKALESRLEKEVKADYDTMNSPPVLKTPSPMEKQASELYTRKLFMRFQEELVGTLTFMASKADDDGDLVTYQVAKYGEAHKAHFVKFNVLEMRANCSCQMFEFSGIICRHILAVFRVTNLLTLPPYYILKRWTRNAKSSVIFDDYNLHAYANYLESHTVRYNTLRHKASNFVQEAGKSLYTCDVAVVALQEAAKTVSLAMNKEVRRTMANRHFKASSVTGGKHQQEVLAQPEPEDEMDKKINQLRNELELANRKCEAYRTNLLSVLKEMEDQKLQVSIKVQNIKISLKDNL
What is the function of this protein?
Putative transcription activator involved in regulating light control of development.
What are the official names of this protein?
Protein FAR1-RELATED SEQUENCE 5.
What is the protein family that this protein belongs to?
Belongs to the FHY3/FAR1 family.
What are the subcellular locations of this protein?
Nucleus. Note=The nuclear localization is independent of the light treatment.
Protein: RS20_PSE14
Sequence: MANTPSAKKRAKQAEKRRSHNASLRSMVRTYIKNVVKAIDAKDAEKAQAAYVLAVPVIDRMADKGIIHKNKAARHKGRLNGHIKALSLAAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: ZBT34_HUMAN
Sequence: MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD
What is the function of this protein?
May be a transcriptional repressor.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 34.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSUG_THEMA
Sequence: MIIESRIEKGKPVVGMETTVFVHGLPRKEAIELFRRAKEISREKGFQLAVIGILKGKIVAGMSEEELEAMMREGADKVGTREIPIVVAEGKNAATTVSATIFLSRRIGIEVVVTGGTGGVHPGRVDVSQDLTEMSSSRAVLVSSGIKSILDVEATFEMLETLEIPLVGFRTNEFPLFFSRKSGRRVPRIENVEEVLKIYESMKEMELEKTLMVLNPVPEEYEIPHDEIERLLEKIELEVEGKEVTPFLLKKLVEMTNGRTLKANLALLEENVKLAGEIAVKLKRS
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: ATPE_STRPC
Sequence: MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAPLQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLRAEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GLMU_STAS1
Sequence: MQRHAIVLAAGKGTRMKSKKYKVLHDVAGKTMIEHVADNVKQSGIDQLVTIVGHGADSVKETLGDTSLYSFQEEQLGTAHAVKMASEHLSESQGTTLVVCGDTPLITTATLKSLVEHHENNQAHATVLSATAENPFGYGRILRDSEGRLVSIVEQKDATDAEQQINEISSGIFAFDNQVLFEKLELVKNDNAQSEYYLPDVLSLILEDRGIVEVFHTNDFEEIMGVNDRVMLSEAEKAFRKRINEQHMKNGVTIIDPVTTYIGADVRIGEDTVVEPGVKLSGNSVIGEDTVIGQHTEITNSKIGSNVTIKQSVINEAIVDDYATIGPFAQLRPGADLGKKVKVGNFVEVKKSVVKAGAKLPHLSYIGDAEIGERTNVGCGSITVNYDGINKFKTVIGDDSFIGCNTNLVAPITLGNRSFIAAGSTITDNVPEDSLALARARQTTKEGYLKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_CHLT3
Sequence: MRRKAASKRLTLTDQRFNDEIIYRLINAVMIDGKKSVATKVVYDAMDIVGEKSEESALDVFHKAMTNISPVVEVRGKRVGGATYQIPMEVRAERRVALALRWLKKYSESRSGKSMATRLAAEILDASNSQGSAVKKREEVHKMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: URE1_RUEST
Sequence: MPANIPRSDYAAMYGPTTGDRVRLADTDLIIEVERDLTGPYGEEVKFGGGKVIRDGMGQAQTTRAGGAVDTVITNALILDWTGIYKADVGLKDGRIHAIGKAGNPDTQPNVTIIVGPGTEVIAGEGRILTAGGFDSHIHYICPQQIEDALHSGLTTMLGGGTGPAHGTLATTCTPGAWHLGRMMQAADAFPMNLAFAGKGNASLPAAIEEQVNAGACALKLHEDWGTTPAAIDCCLGVADAMDVQVMIHTDTLNESGFVEHTVKAMKGRTIHAFHTEGAGGGHAPDIIKICGEEFVLPSSTNPTRPFTVNTIEEHLDMLMVCHHLDKSIPEDVAFAESRIRRETIAAEDILHDMGAFSIIASDSQAMGRVGEVIIRTWQTADKMKKQRGRLSEETGENDNFRVRRYVAKYTINPAIAHGIAHEIGSIEVGKRADLVLWNPAFFGVKPEMVLMGGTIACAQMGDPNASIPTPQPVYSRPMWGAYGRSVEHSAVTFVSEAAQAAGIGKTLGLAKQTLAVKGTRGIGKSALKLNTATPEIEVHPETYEVRANGELLTCQPAEELPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBP_BOVIN
Sequence: MADSPWDEIREKFQTALALSRVELHKNPEKEPYKSKYSARALLEEVKALLGPAPEDEDERPQADDSLGAGEHALGLPAELVEAEGPVAQGAVRRAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRKYRLSHDCVSLYIQAQNNLGILWSEREEIETAQAYLESSEALYNQYMKEIGSPPLDPTEHFLPEEEKLPEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKQCFMEARHCLSAANVIFGQIGKIRTTEDTTEAEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLTGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLIVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT
What is the function of this protein?
Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.
What are the official names of this protein?
KIF-binding protein, KIF1-binding protein.
What is the protein family that this protein belongs to?
Belongs to the KIF-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RM14_DANRE
Sequence: MALSLSGLILPKLMQQRAFSVSSAVSAIQKLTRVRVVDNSTLGNAHHHRPPKVIHVYNKNGVGKVGDRVLLAIKGQKKKAIIVGHKMPGARMTPRFDSNNVVLIEDNGNPTGTRIKAPLPTHLRKLEGEYSKLLAIAQRFV
What is the function of this protein?
May form part of 2 intersubunit bridges in the assembled ribosome.  Upon binding to MALSU1, intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation.
What are the official names of this protein?
39S ribosomal protein L14, mitochondrial, L14mt, MRP-L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ZFP1_ARATH
Sequence: MEPSIKGDQEMLKIKKQGHQDLELGLTLLSRGTATSSELNLIDSFKTSSSSTSHHQHQQEQLADPRVFSCNYCQRKFYSSQALGGHQNAHKRERTLAKRGQYYKMTLSSLPSSAFAFGHGSVSRFASMASLPLHGSVNNRSTLGIQAHSTIHKPSFLGRQTTSLSHVFKQSIHQKPTIGKMLPEKFHLEVAGNNNSNMVAAKLERIGHFKSNQEDHNQFKKIDLTLKL
What is the function of this protein?
May play a role in the regulation of shoot development, downstream of photomorphogenic activation (Probable).  Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development (PubMed:24808098).
What are the official names of this protein?
Zinc finger protein 1, AtZFP1.
What are the subcellular locations of this protein?
Nucleus.