PharMolix/UniProtQA huggingface dataset:
Protein: NAA60_DANRE
Sequence: MTDVVPTTALSEIQLRLLCHDDIDRIKVLCGEWFPIEYPDSWYHDITSNKKFFSLAATFRGGIVGMIVAEIKSRTKVHKEDGDILASSFPVDTQVAYILSLGVVKEFRKHGIGSLLLDSLKEHISTTAQDHCKAIYLHVLTTNNTAIHFYENRDFKQHHYLPYYYSIRGVLKDGFTYVLYINGGHPPWTIFDYIHHIGSALASLSPCSIPQRIYRQAQNLLRSFLPWSGISSKSGIEYSRTM
What is the function of this protein?
N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol.  Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met.  Required for normal chromosomal segregation during anaphase.  May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences.
What are the official names of this protein?
N-alpha-acetyltransferase 60, Histone acetyltransferase type B protein 4, HAT4, N-acetyltransferase 15, N-alpha-acetyltransferase F, NatF.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. NAA60 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Probably forms a intramembrane hairpin-like structure in the membrane.
Protein: SYH_SALEP
Sequence: MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGAEVFGLQGPDIDAELIMLTARWWRALGISEHVSLELNSIGSLEARANYRDALVAFLEQHQETLDEDCKRRMYTNPLRVLDSKNPDVQALLNDAPALGDYLDDDSREHFAGLCKLLDAAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFIASPVVDIYLVAAGAQTQSAAMTLAERLRDEMPGVKLMTNHGGGNFKKQFARADKWGARIALVLGESEVADGTVVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_ENTFA
Sequence: MPNIESAIKRVRTSANANAKNSSQTNAMRTAIKKFEEAVAAGADNVDALYNEAVKAVDMAATKGLIHKNKANRDKIRLSKLAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MUTL_ECO81
Sequence: MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASISSVSRLTLTSRTAEQQEAWQAYAEGRDMDVTVKPAAHPVGTTLEVLDLFYNTPARRKFLRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGTAFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQACEDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQLETPLPLDDEPQPAPRAIPENRVAAGRNHFAEPAVREPVAPRYSPAPASGSRPAAPWPNAQPGYQKQQGEVYRQLLQTPAPMQKPKAPEPQEPALAANSQSFGRVLTIVHSDCALLERDGNISLLSLPVAERWLRQAQLTPGEVPVCAQPLLIPLRLKVSGEEKSALEKAQSALAELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLMSEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RL2_VIBCM
Sequence: MAIVKCKPTSAGRRHVVKVVNADLHKGKPYAPLLEKNSKNGGRNNNGRITVRHIGGGHKQHYRLVDFKRTKDGIPAKVERLEYDPNRSANIALVLYADGERRYIIAPKGLQAGDVIQSGPDAPIKAGNAMPMRNIPVGSTIHNVELTPGKGAQLARSAGAYAQLVARDGAYVTLRLRSGEMRKVLSEGRATIGEVGNAEHMLRELGKAGAARWRGVRPTVRGVVMNPVDHPHGGGEGRTSGGRHPVSPWGVPTKGYKTRSNKRTDKYIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: KO1_GIBFU
Sequence: MSKSNSMNSTSHETLFQQLVLGLDRMPLMDVHWLIYVAFGAWLCSYVIHVLSSSSTVKVPVVGYRSVFEPTWLLRLRFVWEGGSIIGQGYNKFKDSIFQVRKLGTDIVIIPPNYIDEVRKLSQDKTRSVEPFINDFAGQYTRGMVFLQSDLQNRVIQQRLTPKLVSLTKVMKEELDYALTKEMPDMKNDEWVEVDISSIMVRLISRISARVFLGPEHCRNQEWLTTTAEYSESLFITGFILRVVPHILRPFIAPLLPSYRTLLRNVSSGRRVIGDIIRSQQGDGNEDILSWMRDAATGEEKQIDNIAQRMLILSLASIHTTAMTMTHAMYDLCACPEYIEPLRDEVKSVVGASGWDKTALNRFHKLDSFLKESQRFNPVFLLTFNRIYHQSMTLSDGTNIPSGTRIAVPSHAMLQDSAHVPGPTPPTEFDGFRYSKIRSDSNYAQKYLFSMTDSSNMAFGYGKYACPGRFYASNEMKLTLAILLLQFEFKLPDGKGRPRNITIDSDMIPDPRARLCVRKRSLRDE
What is the function of this protein?
Catalyzes three successive oxidations of the 4-methyl group of ent-kaurene giving kaurenoic acid, a key step in gibberellin (GA) biosynthesis.
What are the official names of this protein?
Ent-kaurene oxidase, Cytochrome P450 503A1, Cytochrome P450-4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y585_MYCPN
Sequence: MLVVFKRLGFIVSIFSLTFLSACAAFDKWQEFYINNIPSSTEIHRFNYDLNFSLTFTNRITSNGEAKFSVTYGTGWLIDWKEPDKKKENDPFRAYLATNLHVAASLINPQDYEPYKNKDDAGWTTTFRLGKYTKVSDFVSPNQFGLPNAAQALVNVQTSVIPKTAFAARDFVDYSFPQEQKDKEKRKQQWVKNSHTKNSDVQPFAEFAILEIPLFSKSKVDRKIFNHFIQPAIRTYKQLGDSLNIFANPTLDQLKQNRYYVLGYPFLKNKVSSLFLNQTGKKKGIFRRKYTNIPWKTSYYLN
What are the official names of this protein?
Uncharacterized lipoprotein MPN_585.
What is the protein family that this protein belongs to?
Belongs to the MG067/MG068/MG395 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NDPA_SALHS
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTTTVVEMVAELHRVYSAKNKAYGLFNEESELAQALRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGIVLFCHYRYLAVEYLLVTVLNNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPQSTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELSGVSEVSFSEFTAEKGYELEESFPADRSTLRQLTKYAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGGK
What are the official names of this protein?
Nucleoid-associated protein YejK.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: VATE_FINM2
Sequence: MSNLDNIINEILEDAKKESEHILNDANQEKEKIIETKIDQANQEKDTILKKAESEAKGVYDRHLSQVVLKSRDNALFAKQEVIDSVLQKIKDKLKNMSLEDYKKYLTNSLSKMDLNSDDLLVLQSDKYDSLKNENFNVKLSDETVDSGFCIKRGNVLINNNFSSLVDSMKDELEVEIAKTLFKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: CYAY_SHESW
Sequence: MAMTDTEFHQLADDMFQAIESAIETAIDEQDADVDIDASGNVLQLEFVDGSKIVINKQEPLHEIWVATRFGGYHFGFVEGKWLDGRNGGEFMPFVQDSILRQGGIKLSF
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: EX7L_BACAN
Sequence: MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDFTIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQAKEFAFVRAAQKLEALSPLKVMMRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDH2_SCHPO
Sequence: MSMLSTLRTAGSLRTFSRSACYSFQRFSSTKAAAGTYEGVKNANGNYTVTMIAGDGIGPEIAQSVERIFKAAKVPIEWERVKVYPILKNGTTTIPDDAKESVRKNKVALKGPLATPIGKGHVSMNLTLRRTFGLFANVRPCVSITGYKTPYDNVNTVLIRENTEGEYSGIEHEVIPGVVQSIKLITRAASERVIRYAFQYARQTGKNNITVVHKATIMRMADGLFLECAKELAPEYPDIELREEILDNACLKIVTDPVPYNNTVMVMPNLYGDIVSDMCAGLIGGLGLTPSGNIGNQASIFEAVHGTAPDIAGKGLANPTALLLSSVMMLKHMNLNDYAKRIESAIFDTLANNPDARTKDLGGKSNNVQYTDAIISKLK
What is the function of this protein?
Performs an essential role in the oxidative function of the citric acid cycle and is involved in glutamate biosynthesis (PubMed:7903653).  Also binds RNA; specifically to the 5'-untranslated leaders of mitochondrial mRNAs (PubMed:10975257).
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial, Isocitric dehydrogenase, NAD(+)-specific ICDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: DCUP_PASMU
Sequence: MTALKNDRYLKALLREPVDMTPVWMMRQAGRYLPEYRATRAVAGDFMSLCRNAELACEVTLQPLRRYPLDAAILFSDILTIPDAMGLGLSFGVGEGPKFAHPIETQRAVQNLPIPDPEGELQYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTKIKKMLYADPQLLHQLLDKLADAVILYLNAQIKAGAQSVMIFDTWGGVLGHREYLDFSLHYMHKIVAGLIRENEGRKVPVTLFTKGGGMWLEAMAETGCDALGVDWTVNLAQAKARVGHKVALQGNMDPSVLYASPARIEQEVRSILADFGEGSGHVFNLGHGIHQDVPEQSPAVFVNAIHQFSQPYHK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WCAB_ECO57
Sequence: MLEDLRANSWSLRPCCMVLAYRVAHFCSVWRKKNVLNNLWAAPLLVLYRIITECFFGYEIQAAATIGRRFTIHHGYAVVINKNVVAGDDFTIRHGVTIGNRGADNMACPHIGNGVELGANVIILGDITLGNNVTVGAGSVVLDSVPDNALVVGEKARVKVIK
What are the official names of this protein?
Putative colanic acid biosynthesis acetyltransferase WcaB.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: MURB_ECO57
Sequence: MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQHATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKGMQMGGVAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGEVSAVETIS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPHP1_HUMAN
Sequence: MLARRQRDPLQALRRRNQELKQQVDSLLSESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSKADESAPVANYNQRKEEEHTLLDKLTQQLQGLAVTISRENITEVGAPTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIAVGDFTAQQVGDLTFKKGEILLVIEKKPDGWWIAKDAKGNEGLVPRTYLEPYSEEEEGQESSEEGSEEDVEAVDETADGAEVKQRTDPHWSAVQKAISEAGIFCLVNHVSFCYLIVLMRNRMETVEDTNGSETGFRAWNVQSRGRIFLVSKPVLQINTVDVLTTMGAIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDGNKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFYRQILGDVLLKDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARWKVITDFLKQNQENQGALQALLSPDGVHEPFDLSEQTYDFLGEMRKNAV
What is the function of this protein?
Together with BCAR1 it may play a role in the control of epithelial cell polarity (By similarity).  Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 (By similarity).  Does not seem to be strictly required for ciliogenesis (By similarity).  Seems to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling (By similarity).  May play a role in the regulation of intraflagellar transport (IFT) during cilia assembly.  Required for normal retina development (By similarity).  In connecting photoreceptor cilia influences the movement of some IFT proteins such as IFT88 and WDR19.  Involved in spermatogenesis (By similarity).
What are the official names of this protein?
Nephrocystin-1, Juvenile nephronophthisis 1 protein.
What is the protein family that this protein belongs to?
Belongs to the nephrocystin-1 family.
What are the subcellular locations of this protein?
Cell junction. Cell junction, adherens junction. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cell junction, tight junction. Note=In the retinal photoreceptor cell layer, localizes at the connecting cilium (By similarity). Colocalizes with E-cadherin and BCAR1 at or near the cell-cell adherens junctions (By similarity). Localized to respiratory cilia axoneme (PubMed:16308564, PubMed:16885411). Localized to the transition zone of respiratory cilia (PubMed:16885411). Localized to the transition zone of photoreceptor-connecting cilia and renal monocilia (By similarity). In cultured renal cells, it localizes diffusely in the cytoplasm but, as cells approach confluence, it accumulates at basolateral tight junctions (By similarity).
Protein: PAND_MYCA1
Sequence: MLRTMLKSKIHRATVTQADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYGTMEEAEARAYQPRIVFVDADNKPVDLGHDPAFVPDFEIAGAAELLDPRIVAR
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXO1_ARATH
Sequence: MKGNWSIVRKVLHRQFSTLRSSTPSSRLSTSIRPLVLAPNSISSLIARNSLFTASNIGPSIDFNFSNTSLPHRRSLCSEAGGENGVVLVKSEEEFINAMSKAQDGSLPSVFYFTAAWCGPCRFISPVIVELSKQYPDVTTYKVDIDEGGISNTISKLNITAVPTLHFFKGGSKKGEVVGADVTKLKNLMEQLYK
What is the function of this protein?
Thiol-disulfide oxidoreductase that may participate in various redox reactions.  Possesses insulin disulfide bonds reducing activity.  Reduced by thioredoxin reductases NTRA and NTRB.
What are the official names of this protein?
Thioredoxin O1, mitochondrial, AtTrxo1.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant O-type subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL35_BACCQ
Sequence: MPKQKTHRGAAKRFKKTGSGKLKRSHAYTSHLFANKSTKAKRKLRKAGVVSAGDFKRIRQMLDNLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: P10_NPVAC
Sequence: MSKPNVLTQILDAVTETNTKVDSVQTQLNGLEESFQLLDGLPAQLTDLNTKISEIQSILTGDIVPDLPDSLKPKLKTQAFELDSDARRGKRSSK
What is the function of this protein?
Plays a role in the proper virion occlusion of the polyhedra.  Forms extensive fibrillar structures in both host nucleus and cytoplasm.  Involved in the liberation of polyhedra from infected insect cells.
What are the official names of this protein?
Protein p10, Fibrous body protein.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: MET_ATEGE
Sequence: MKAPTVLTPGILVLLFILVQRSNGECKEALTKSEMNVNMKYQLPNFTAETPIQNVVLHEHHIFLGATNYIYVLNEEDLQKVAEHRTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQTEEPSQCPDCVVSALGTKVLLSVKDRFLNFFVGNTINSSYFPDHSLHSISVRRLKETKDGFMFLTDQSYVDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLNAQTFHTRIIRFCSINSALHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAVCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTFQRNLLGCEARRDEYRTEFTTALQRIDLFAGQFNKVLLTSISTFVKGDLTIANLGTSEGRFIQIVVSRSVPSTPHVNFLLDSHPVSPEVIVEHPLNQNGYTLVVTGKKITKIPLNGLGCRHFQSCSQCLSAPSFVQCGWCHDKCVRSEECSSGTWTQETCLPTIYRVFPTSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNEHFNMSIIISNTHGTTQYSTFSYVDPIITSISPRYGPMSGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFPVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGIGKNLNSVSVPRMVINLHEARRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPSDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISIALLLLLGLFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSAFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNADGEVDT
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: HXA11_CHICK
Sequence: MMDFDERVPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREVTFREYAIDPSSKWHPRNNLPHCYSAEEIMHRDCLPSTTTASMGEVFGKSTANVYHHPSANVSSNFYSTVGRNGVLPQAFDQFFETAYGTAENPSSADYPPDKSGEKAPAAAGATAATSSSEGGCGGAAAAAGKERRRRPESGSSPESSSGNNEEKSGSSSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A11, Ghox-1I, Homeobox protein Hox-1.9, Chox-1.9.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACPX_STRVN
Sequence: MARLTLDGLRTILVACAGEDDGVDLSGDILDITFEELGYDSLALMESASRIERELGVALADGDINEELTPRVLLDLVNGAQAEAA
What is the function of this protein?
Acyl carrier protein.
What are the official names of this protein?
Granaticin polyketide synthase acyl carrier protein, ACP.
Protein: RSMG_STAAW
Sequence: MTVEWLAEQLKEHNIQLTETQKQQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNHLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_SHESA
Sequence: MQGSVTEFLKPRLVDIEQVNSTRAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSKEGVQEDILEILLNLKGLAVTIEGKDEAMLTLSKSGAGPVIAADITHDGDVTIVNPDHVICHLTGNNDISMRIRVERGRGYVPASARAQTEDDDRPIGRLLVDASFSPVARIAYNVEAARVEQRTDLDKLVIDMTTNGTIDPEEAIRRSATILAEQLDAFVELRDVTEPEMKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASLADDL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: VPC43_MYCTO
Sequence: MLCVDVNVLVYAHRADLREHADYRGLLERLANDDEPLGLPDSVLAGFIRVVTNRRVFTEPTSPQDAWQAVDALLAAPAAMRLRPGERHWMAFRQLASDVDANGNDIADAHLAAYALENNATWLSADRGFARFRRLRWRHPLDGQTHL
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB43 (By similarity).
What are the official names of this protein?
Ribonuclease VapC43, RNase VapC43, Toxin VapC43.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: FMT_ECO81
Sequence: MSESLRIIFAGTPDFAARHLDALLSSGHNIVGVFTQPDRPAGRGKKLMPSPVKVLAEDKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTTTKAAPGTILEANKQGIQVATGDGILNLLSMQPAGKKAMSVQDLLNSRREWFVPGNRLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: TMCO4_HUMAN
Sequence: MAMWNRPCQRLPQQPLVAEPTAEGEPHLPTGRELTEANRFAYAALCGISLSQLFPEPEHSSFCTEFMAGLVQWLELSEAVLPTMTAFASGLGGEGADVFVQILLKDPILKDDPTVITQDLLSFSLKDGHYDARARVLVCHMTSLLQVPLEELDVLEEMFLESLKEIKEEESEMAEASRKKKENRRKWKRYLLIGLATVGGGTVIGVTGGLAAPLVAAGAATIIGSAGAAALGSAAGIAIMTSLFGAAGAGLTGYKMKKRVGAIEEFTFLPLTEGRQLHITIAVTGWLASGKYRTFSAPWAALAHSREQYCLAWEAKYLMELGNALETILSGLANMVAQEALKYTVLSGIVAALTWPASLLSVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGRRPVTLIGFSLGARVIYFCLQEMAQEKDCQGIIEDVILLGAPVEGEAKHWEPFRKVVSGRIINGYCRGDWLLSFVYRTSSVQLRVAGLQPVLLQDRRVENVDLTSVVSGHLDYAKQMDAILKAVGIRTKPGWDEKGLLLAPGCLPSEEPRQAAAAASSGETPHQVGQTQGPISGDTSKLAMSTDPSQAQVPVGLDQSEGASLPAAASPERPPICSHGMDPNPLGCPDCACKTQGPSTGLD
What are the official names of this protein?
Transmembrane and coiled-coil domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the TMCO4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.