PharMolix/UniProtQA huggingface dataset:
Protein: UXUA_ECOBW
Sequence: MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIIEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSR
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: SECA_CAMC1
Sequence: MISSVFRKIFGTKNDREVKKYIKRVAQINALEPTYEKMSDDELKIKFNELKAQVVEEKVTLDQILNDVFALVREASKRVLKMRHFDVQLIGGMVLNEGRIAEMKTGEGKTLVATLPVILNAMSGKGVHVVTVNDYLAKRDATQMGELYNFLGLSVDVILSGGYDDEVRQAAYNADITYGTNSEFGFDYLRDNMKFEAGQKVQRGHNFVIVDEVDSILIDEARTPLIISGPTNRTLDGYIRADQVAKQLTRGTPADPNMPGSKPTGDFIVDEKNRTIMITEAGISKAEKLFGVENLYNLENAVLSHHLDQALKAHNLFEKDVHYVVKDGEVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVKIQEESQTLADTTYQNYFRMYKKLAGMTGTAQTEATEFSQIYNLEVISIPTNVPVKRIDQNDLIYKTQNEKFKAVIDEVKKAHEKGQPVLVGTASIERSEVLHEMLKKAGIPHSVLNAKNHEKEAEIIAQAGVKGAVTIATNMAGRGVDIRINDEVRDLGGLYIIGTERHESRRIDNQLRGRAGRQGDPGMSRFYLSLEDNLLRIFGSDRIKAIMDRLGIDEGESIESRMVTRAVENAQKKVESLHFEARKHLLEYDDVANEQRKTIYKYRDELLDKNYDMSEKIAQNRVEYATNLLDTAEIFHGGLKDDYDIKNLCSIILADCGEEIDESELKGLEYNELVEKIAQILEVRYNEKMSVLNEEQRKDIEKILYLQVLDNAWREHLYQMDILKTGIGLRGYNQKDPLVEYKKESYNLFMELVGRLKTESVKTLQIVRFKSREEQEEQARMMLEASQNAENEPLNYNNQGEDENFTPEKKIPRNAPCPCGSGKKYKDCHGKSGPKKGIFA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MIAA_MAGMM
Sequence: MGPTASGKTGLALHLAEHFPLEIVNADSVQVYRGMDIGSAKPTLQERQAIVHHLIDVTTPDDPFSAGRFRTAALEVIEDCHRRGVIPALVGGTGFYFRAVEQGIAEIPEVDAQIVAELNRRVCDEVGLACCYAQLQQVDPPWAARVEPGDRQRIVRGLSVYLASGQPLSYWQQLSCQQAPEGPALRICKLAIEWPREQLYARINQRFEQMLKEGFMEEVQGLLSRGYHGDLPAMRAVGYRALIGYLQGAYDLARAVELGQRDSRRYAKRQITWLKAEPGLQWLAPEGAKQAALDEVRAFLQFFKKK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MNME_CHESB
Sequence: MPDQIPVRDTIFALSSGSLPSGIAVIRISGADTRAVLERMAGGLSEARFAKLTSIYSAEREVLDRALCLFFPAPASFTGEDCAELHLHGGRAVVAAVLNELAAFPGLRMAEAGEFTKRAFLNGKMNLTEAEALSDLIAAETEAQRRFALVNSSDMRKRLYDGWRRRLIHARAMIEAELDFADESDVPGSAGATVWEDIRRLRQEIVEHASSYRKAEIIRDGFQIVILGAPNAGKSSLLNALARRDVAIVTEEPGTTRDILEVSLDIDGTKVVLADTAGIREAAGRVEALGIERSLRRANEADLVLLLEDVTNPSTPEVPQGKPVITIGNKADLITDTPAASYNCLISAKTGLGLDRLMELISQASAGYSNFAGEILPFRERHVALLGQAADALEAGIDGENIGLELRAECLRLSSLALGRISGEIDVEDLLDAIFSTFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSM10_MOUSE
Sequence: MALSHSVKERTISENSLIILLQGLQGQITTVDLRDESVARGRIDNVDAFMNIRLANVTYTDRWGHQVELDDLFVTGRNVRYVHIPDGVDITATIEQQLQIIHRVRNFGGKGQGRREFPSKRP
What is the function of this protein?
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing (By similarity).  Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed (By similarity).  Required for cell cycle progression from G1 to S phases (By similarity).  Binds specifically to U7 snRNA (By similarity).  Binds specifically to U7 snRNA (By similarity).  Binds to the downstream cleavage product (DCP) of histone pre-mRNA.
What are the official names of this protein?
U7 snRNA-associated Sm-like protein LSm10.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_HALSA
Sequence: MLSRQFVREHPEKVRDALDAKGVDADLDRILEVDEEWRELKARGDELRHDRNEVSSKIGELKQAGDEDAAQEAIERSQALKDELADVEARADDLEAELERLLLTLPMVPDEDAPVGDSEAENVERRREGFDDRRDLPESVVPHYDLGEELDILDFERGAKVSGGGFYFSKGAGARLEHALVQFMLDVHREQGYEDVFPPMPVSARSMEGTGQFPKFVEDAYRIGGENDADYDDDDLWLLPTAEVPVTNMYRDEILLDDDLPVKHQAYSPNFRREAGEHGTETRGIVRVHQFNKVELVNFVRPEDSAERFHGLLDEAEAVLRRLDLPYRVLEMCTGDMGFTQAKKYDIEVWAPGDDMDGGPEMGGRWLEVSSVSNFKDFQARRADIQYRPERHESAEHLHTLNGSGVAVPRVLVAILEYYQNDDGTVTVPEALQPYMNGQTRIEGSRKVGESALGDGDREA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMDA_MYCSM
Sequence: MPEVVFSVDHSKSMRDQAVPGHNRWHPDIPAAATVKPGSEFRIECKEWTDGQIGNNDSANDVRDVDLAPCHMLSGPIKVEGAEPGDLLIVDILDIGPVPQTNGPNCGEGWGYSGIFAKVNGGGFLTDYYPDAYKAIWDFHGQQCTSRHVPGVRYTGITHPGLFGTAPSPDLLAKWNERERALIATDPDRVPPLALPPLVDGTLGGTASGDLLQAIANDGARTVPPRENGGNHDIKNFTRGSRIFYPVFVEGAMLSGGDLHFSQGDGEINFCGAIEMGGFIDMHVDLIKGGMETYGVTTNPIFMPGRVEPLYSEWLTFIGISVDHAENRNAYMDATMAYRNACLNAIEYLKKWGYTGEQAYLILGTSPIEGASAASWTSRTHVVRCSCRPRSSTSTSPRRQGPAEGR
What is the function of this protein?
Allows acetamide to be used as a sole carbon or nitrogen source.
What are the official names of this protein?
Acetamidase.
What is the protein family that this protein belongs to?
Belongs to the acetamidase/formamidase family.
Protein: HTPX_METJA
Sequence: MINQIKTYLLMALLVGLIYAICMMLHIHPLIAIILALIPNVIAYYMSDKLVLMSYNARILEEHEMPWLHQMVERVARKAGLPKPKVAIVPTETPNAFATGRNPENAVVAVTEGILKLLSPEELEGVIGHEISHIKHRDILISTIVATLAGAIVMIAEWMLYWGGIFFVSEEEESNPLELIGTILLLILAPIAATIIQFAISRQREFYADEEGAKLTHPLWLANALAKLERGVELYPLERGNPATAHMFIINPFRKDFIAKLFSTHPPTEERIERLLEMCKRIGK
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDUQ_SALTY
Sequence: MNTFSLQTRLYSGQGSLAVLKRFTNKHIWIICDGFLAHSPLLDTLRNALPADNRISVFSEITPDPTIHTVVQGIAQMQALQPQVVIGFGGGSAMDAAKAIVWFSQQSGINIETCVAIPTTSGTGSEVTSACVISDPDKGIKYPLFNNALYPDMAILDPELVVSVPPQITANTGMDVLTHALEAWVSPRASDFTDALAEKAAKLVFQYLPTAVEKGDCVATRGKMHNASTLAGMAFSQAGLGLNHAIAHQLGGQFHLPHGLANALLLTTVIRFNAGVPRAAKRYARLAKACGFCPAEANDIAAINALIQQIELLKQRCVLPSLAVALKEGRSDFSARIPAMVQAALADVTLRTNPRPANAEAIRELLEELL
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
1-propanol dehydrogenase PduQ, Propanediol utilization protein PduQ.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Bacterial microcompartment. Note=Probably located inside the BMC shell.
Protein: YONS_BACSU
Sequence: MKLFKKLGILLLITSLILLAACKNSEESSSSSEDTNNATDTNTSESQDISVNGPEKVGDVYEIDGGTAKVMAISNKETTVKTGPIQFTVKKVIAAVANEQLPFIDVQIESENTSDEVVRFRPSLAQLATSTGVQIDEPSLLESDRLLDEYVGKVNDSGSIIYVFDNEEDIKDLESIRLRISSPFNEDLKNLGDKLDLKINLEH
What are the official names of this protein?
SPbeta prophage-derived uncharacterized lipoprotein YonS.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL9_DECAR
Sequence: MQIILLEKVVNLGNLGDIVKVKDGYARNFLIPQRMAKRATPAAMAEFEARRAELEKLAAEKLAAAQAVADKMNGTVVTVARKAGMDGRLFGSVGNADIADALKAAGYVVDKSAVRMPEGPLKAIGEFPLDVALHTDVLANITVAIVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PTN2A_ARATH
Sequence: MSSESPNLPAAAGTVPDNHPPPPPVVTAAEAGSDDSPKGVASKLSAAGISNWAKNLKVPQPFASTQNDSGVENTEKSAFAKFTSGLGIRLSPKSPQTNDTTTEGTSSATESSFIGTITKGLVDTSKNAVKAVQVKARHAVSQNKRRYQEGGFDLDLTYITENIIAMGFPAGDMSSGFFGYVEGFYRNQMEEVINFLETQHKGKYKVYNLCSERLYDVSLFEGKVASFPFDDHNCPPIHLVTSFCQSAYSWLKEDIENVVVVHCKAGMARTGLMICSLLLYLKFFPTAEECMDFYNQKRCVDGKGLVLPSQIRYVKYFERILTYFNGENQPGRRCMLRGFRLHRCPYWIRPSITISDHNGVLFTTKKHPRTKDLSPEDFWFSAPKKGVMVFALPGEPGLTELAGDFKIQFHDRQGDFYCWLNTTMMENRVILKTSELDGFDKRKLPSPGFMVEVVLADINATIPTNPSSETASKTPEETSAANSSPVDGSASVPGPDKETENPDKDDVFSDNEGDSTGPTKTTSSASSQTPEAKKSADETAVLTKATEKVSISGNKGSSQPVQGVTVSKGEATEKPSGAGVNASSSSESEFKVMAADASVFSFGDEDDFESD
What is the function of this protein?
Binds phosphatidic acid.  Protein tyrosine phosphatase that exhibits also lipid phosphatase activity.  Hydrolyzed poorly p-nitrophenyl phosphate (p-NPP).  Can use PtdIns isomers as substrates.  Removes efficiently phosphate from the D3 position of the inositol ring, less from the D4 position and not at all from the D5 position on monophosphorylated PtdIns isomers (PIPs).  The presence of a phosphate group in the D5 position on PIP(2) isomers reduces lipid phosphatase activity.  Mostly active on PtdIns(3)P and PtdIns(3,4)P(2), to a lower extent, on PtdIns(4)P and PtdIns(3,5)P(2), but barely against PtdIns(3,4,5)P(3) as substrate.
What are the official names of this protein?
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN2A, Protein PHOSPHATASE AND TENSIN HOMOLOG 2-a, AtPTEN2, AtPTEN2a.
What is the protein family that this protein belongs to?
Belongs to the PTEN phosphatase protein family.
Protein: FAAA_EMENI
Sequence: MASWLQIPKNSPFSLANIPFGIISSSKLSSRVPAIAIGDYALDLSKFASSGGFSQLPVIQPHLNVFNQSTLNAFAALGRPVHRQVREYIQKVFSTETPFPQILRDNAALQKEALLPLSEVTNHLPMQIGDYTDFYAGLNHAYNVGVLFRGPDNALQPNYKHLPVAYHGRASSVVTSGTPLHRPQGQILTNPAANPKLPTFSPCKKLDIELELAFFVSTPNDLGHPVHIDKAEDHIFGVVLMNDWSARDIQAWEYVPLGPFNAKNFGTTITPWVVLIDALEPFRTVGLEPGNRESLLPYLREKRADTAYDIPLEVEVTNAGGEPTVISHSNAKNLLYSFPQMLAHHTITGCNLNTGDLLGSGTISGKENQTEGSFLEQTNGKNPIKLADGSERLFLEDGDTVILRGMAGTEGNYVGFGDCAGTILPPVQLDL
What is the function of this protein?
Use of phenylalanine and phenylacetate as a carbon source.
What are the official names of this protein?
Fumarylacetoacetase, FAA, Beta-diketonase, Fumarylacetoacetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: FTSB_YERPS
Sequence: MGKLTLLLLVLLGWLQYSLWLGKNGIHDFVRVKEDVAAQEANNSTLKARNDQLFAEIDDLNGGQEAIEERARNELGMIKPGESFYRLVPDQSRRNAGTPSTQNNAQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: GRCA_SHIF8
Sequence: MITGIQITKAANDDLLNSFWLLDSEQGEARCIVAKAGYAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: HUTG_CHRVO
Sequence: MVDMKIWTGRVDAAEGEAAKRWHQAVQAMPENGAPGIAIIGFACDEGVRRNQGRVGAAGGPKTLRKALANLAYHPTLPLYDAGDVACADGDLAAAQQRLGERVAQVIAAGHLPLVLGGGHETAYGHWLGLSAAHPDKRIGVINFDAHFDLRQASEATSGTPFAQIAADCARHGRVFRYLCLGVAETANTQALFDTARRLGAEWRLDTDMNGWQLADIRGQLAEFLDSVDAVYLTIDLDVLPAAQMPAVSAPAGYGVDIAVVEALAGRIAKSGKLAGADLVEFNPDYDIDSHGAKAAARLAWSLSRHLRR
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: Y1285_SHEPW
Sequence: MKVWVDADACPGVTKETLFRAADRAEIETILIANHSVRIPPSRFIKMVTVSSGFDVADDEIVKRLTAGDLVITADIPLAAEVIEKGGLALNPRGELYTEQNIKSILNMRDFMDTMRASGVQTGGPAAMSQSERQAFANQLDRLITKFKQQKK
What are the official names of this protein?
UPF0178 protein swp_1285.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: NCFA_DICDI
Sequence: MLKQTIKKWNQSIERYESGNVGEALTILTSIEQSTSKINYNIGVMYIKSNNFRNAIEYFNRSVEQDKYLASSYYMRAIAHHMNGELNHAIVDYDETISKLRGHEYIDYKQLGLDHKLLLAEVLFNKALALGRAGSSVALQATQCFSQPSDSQEFKNQCKKIQDGSQLNFSTRPIPLSLLFKPPKVSDAPQKQRSATTSSIQSSSPSTPMSSSPPSYILKGPSSPPSSSSPSSSSPSLSSSSSPKLPPTPKPSFGSSPPPSSSSSSSSSSSSSSSSISPLTNKTLPPKPPPLPSKKLPSRPISCVIQDVKITLKVFYKDRRLIQIPVPCNLSTFIQKIELKFEITISDKFSLSFQLDGEENEINSQVQLDKMICMEINEINVKDIIPSPSPSPSPSPDKTNNSTSSYSSSSSSSSSSSSSSSSSSYDNKPKSSFIPKTTTRPILPPTTTTTTSTSNNFNRNATLPKKFGSTPSSPSFSSPSSSSSGGGGGPPIPTRGSPSISLLKQQNQTQSINIPPKVPTSSRPKMTQSHSPPSSSPLSSYSTSFQSVSSPSLSSSYNGSTSSYGGFSSSRPPPTPYPYQVLYTDSNEKYYLNTETNETFWELP
What is the function of this protein?
May function as an activator of NOX1, a superoxide-producing NADPH oxidase.
What are the official names of this protein?
NADPH oxidase activator, NOX activator, p67-phox-like factor.
Protein: DCTA_YERPN
Sequence: MKVSIFKTLYFQVLTAITIGVLLGHFYPEIGAQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAIALLYFEIVSTLALLIGLVVVNVAQPGVGMNIDPATLDAKAVALYAEQASQQGIIPFLLDIIPGSVVGAFASGNILQVLLFAVLFGFALHRLGEKGQLIFNVIESFSRVIFGVINMIMRLAPLGAFGAMAFTIGKYGVGSLVQLGQLILCFYLTCILFVVLVLGTIAKFNGFNIFKFIRYIKEELLIVLGTSSSESVLPRMLDKMENAGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTHMDIMHQVTLLVVLLLSSKGAAGVTGSGFIVLAATISAVGHLPLAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWCKQLDNDQLQAVLSNKVLPNVKSSVSVS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCNJ1_MOUSE
Sequence: MFKHLRRWFVTHIFGRSRQRARLVSKDGRCNIEFGNVDAQSRFIFFVDIWTTVLDLKWRYKMTVFITAFLGSWFLFGLLWYVVAYVHKDLPEFYPPDNRTPCVENINGMTSAFLFSLETQVTIGYGFRFVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTITPEGETIILDQTNINFVVDAGNENLFFISPLTIYHIIDHNSPFFHMAAETLSQQDFELVVFLDGTVESTSATCQVRTSYIPEEVLWGYRFVPIVSKTKEGKYRVDFHNFGKTVEVETPHCAMCLYNEKDARARMKRGYDNPNFVLSEVDETDDTQM
What is the function of this protein?
In the kidney, probably plays a major role in potassium homeostasis.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  This channel is activated by internal ATP and can be blocked by external barium (By similarity).
What are the official names of this protein?
ATP-sensitive inward rectifier potassium channel 1, ATP-regulated potassium channel ROM-K, Inward rectifier K(+) channel Kir1.1, Potassium channel, inwardly rectifying subfamily J member 1.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Phosphorylation at Ser-44 by SGK1 is necessary for its expression at the cell membrane.
Protein: LNT_NOSS1
Sequence: MGLTVAPFAAWFLAWIALAPLWIFVVSSKRKNYPPSSLLLLGLTWGIGYHGVALFWITGIHPMDWLGVPWWPSLAITIFCWSFISFYGGLFGAIWAACLTHISEQKSWLRILIGTAMWCVLESLWSAGPLWWSSLAYTQSPHNLAILHLGQISGPNLVTAAIVSVNGIVAEAWLNRKQGLLGRYLAIATGLLITLHLIGFGLYTAPIAKSSDTALKVGIVQGNIPNKIKLLPQGLSRAITGYTDGYLTLVNQGVEAVLTPEGALPFFQRNLPTTPLVSAVREKGVVAWIGAFGDRGRSYTNSLFTVNSQGEITSRYDKSKLVPLGEYIPFEGIIGGLVQRLSPLDEHQVHGSPNQIFDTPFGRAIVGICYESAFPEVFRSQAAAGGQFILSSSNDAHYSAAMPFQHHAQDIMRAIETDRWSARATNTGYSAFVDPHGRTLWISGYNTYETHAETIYRRQTQNLYVRWGDWFTPLLVGLSFLGWSLNIFWRNDANANSKLR
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BL1S3_DROME
Sequence: MADLVSGEASESDEELQEKNKIFAAEISGEASEEDDEDIYEQGRSSNQVNSTASIYRNNLLQRKLIENNIAIWRSLTAFTRSFVLSASKQLVTTDQMLIKSQHSLQSAHTSLQQAQKNAQDLQNRVADVITSNFLPHISIQKAT
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 3, BLOC-1 subunit 3.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S3 family.
Protein: IFNT7_SHEEP
Sequence: MAFVLSLLMALVLVSYGPGGSLGCYLSRRLMLDARENLRLLDRMNRLSPHSCLQDRKDFGLPQEMVEGDQLQKDQAFPVLYEMLQQSFNLFYTEHSSAAWDTTLLEQLCTGLQQQLDHLDTCRGQVMGEKDSELGKMDPIVTVKKYFQGIHDYLQEKGYSDCAWEIVRVEMMRALTSSTTLQKRLTKMGGDLNSP
What is the function of this protein?
Paracrine hormone primarily responsible for maternal recognition of pregnancy.  Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium.  This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity.  This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus.  In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties.  In contrast with other IFNs, IFN-tau is not virally inducible.
What are the official names of this protein?
Interferon tau-7, IFN-tau-7, Antiluteolysin, TP-07, Trophoblast antiluteolytic protein, Trophoblast protein 1, TP-1, Trophoblastin.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the uterine lumen.
Protein: RRF_PROMH
Sequence: MINEIKKDAQERMDKSVEALKSQINKVRTGRASPNLLDGIVVEYYGAPTPLNQVANVVAEDGRTLAITVFDRTLAPAVEKAIMASDLGLNPSSAGAIIRVPLPPLTEERRKDLIKVVRGDAEQGRVSIRNIRRDANDKIKALLKDKEISEDDERRSQDEIQKLTDMFIKKIDEALTLKEAELMEF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBI_CROS5
Sequence: MLTLKIAVYIVVAFFISLFVFGFLSSDPTRNPGRKDFE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MTAB_CHLPN
Sequence: MTVAEVKGTFKLVCLGCRVNQYEVQAYRDQLTILGYQEVLDSEIPADLCIINTCAVTASAESSGRHAVRQLCRQNPTAHIVVTGCLGESDKEFFASLDRQCTLVSNKEKSRLIEKIFSYDTTFPEFKIHSFEGKSRAFIKVQDGCNSFCSYCIIPYLRGRSVSRPAEKILAEIAGVVDQGYREVVIAGINVGDYCDGERSLASLIEQVDQIPGIERIRISSIDPDDITEDLHRAITSSRHTCPSSHLVLQSGSNSILKRMNRKYSRGDFLDCVEKFRASDPRYAFTTDVIVGFPGESDQDFEDTLRIIEDVGFIKVHSFPFSARRRTKAYTFDNQIPNQVIYERKKYLAEVAKRVGQKEMMKRLGETTEVLVEKVTGQVATGHSPYFEKVSFPVVGTVAINTLVSVRLDRVEEEGLIGEIV
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MtaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.