PharMolix/UniProtQA huggingface dataset:
Protein: PYS1_MICDP
Sequence: MLGSVLTRRSSSGSDNRVFVYEVEGLRQNEQTDNNRYQIRNSSTIEIQVPYSRMNEEDRRITRLGGRIVNIRPAGENPTEDASEN
What is the function of this protein?
Rod linker protein, associated with phycocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome 9.7 kDa linker polypeptide, phycocyanin-associated, rod, L-9.7/R, Rod-capping linker protein.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=This protein occurs in the rod, it is associated with phycocyanin.
Protein: SEQA_GLAP5
Sequence: MKTIEVDDELYHYIASRTQAIGESASDILRRLLRLPASPQPFVLVQENMINELKDLAKLPKQKKQLHQQDKVIKQVEFVLASSLFNNETKGVNRFLYLLSALYKADPESFSHATENVQGSERIYFARDEQTILATGSSVKAKQIPESPFWVITNNNTERKGIILCALMNAMELPEELVARIKAQFN
What is the function of this protein?
Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle.  Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins.  Repression is relieved when the region becomes fully methylated.
What are the official names of this protein?
Negative modulator of initiation of replication.
What is the protein family that this protein belongs to?
Belongs to the SeqA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRX5_HAEIN
Sequence: MSSMEGKKVPQVTFRTRQGDKWVDVTTSELFDNKTVIVFSLPGAFTPTCSSSHLPRYNELAPVFKKYGVDDILVVSVNDTFVMNAWKEDEKSENISFIPDGNGEFTEGMGMLVGKEDLGFGKRSWRYSMLVKNGVVEKMFIEPNEPGDPFKVSDADTMLKYLAPQHQVQESISIFTKPGCPFCAKAKQLLHDKGLSFEEIILGHDATIVSVRAVSGRTTVPQVFIGGKHIGGSDDLEKYFA
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Hybrid peroxiredoxin hyPrx5, Glutathione-dependent peroxidase, Glutathione-dependent peroxiredoxin, Peroxiredoxin-glutaredoxin fusion protein, PGdx, Prx-Grx.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glutaredoxin family.
Protein: REEP4_HUMAN
Sequence: MVSWMICRLVVLVFGMLCPAYASYKAVKTKNIREYVRWMMYWIVFALFMAAEIVTDIFISWFPFYYEIKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDAYIVQAKERSYETVLSFGKRGLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSISDAPAPAYHDPLYLEDQVSHRRPPIGYRAGGLQDSDTEDECWSDTEAVPRAPARPREKPLIRSQSLRVVKRKPPVREGTSRSLKVRTRKKTVPSDVDS
What is the function of this protein?
Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis.  Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes.
What are the official names of this protein?
Receptor expression-enhancing protein 4.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
Protein: MDH_PLAVE
Sequence: AQTPVKVTVTGAAGQIGYALLFRI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: ZAPD_BURPS
Sequence: MILYEYPFNERIRTLLRLEDLFERFTFFVAQEDAREHHVALTTLFEISEVAGRADLKSDLMKELERQRQTLAPFRGNPGIEQNALEAVLGEIEQTLANLAQMQGKTGQHLIDNEWLASIRSRAVIPGGTCKFDLPSYYAWQQWPAEQRRHDIAKWAMPLLPLRDAAMIVLRLARESGQASKVMAMQGSYQQMLSGRTYQLMQVRVPPELRVIPEASANKYMLWVRFTAQDGDVRPRAVDIDVPFQLTLCNL
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: PYRB_LACLS
Sequence: MSVKNGLVQLENLTSMENLSVDEVMGLIKRASAFKAGKADFALDEQTFASNLFFENSTRTHHSFHIAERKLGLDVLEFDAQASSISKGETLYDTVLTLDALGVDICVIRSGVEHYYEELVNSDNIHCAIVNGGDGSGQHPSQCLLDLMTIYEEFGKFEGLKIAISGDLTHSRVAKSNMMMLQKLGARLYFTGPAAWYSEEFDDYGHYANLDRILPELDVHMLLRVQHERHDSGESFSKEGYHTHFGLTQERAKMLKPTAIIMHPAPVNRDVEIADSLVESPQSRIVQQMSNGVYTRMAILEAILAGKKAK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: GUAA_STRPF
Sequence: MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGKVVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSNDCPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAKIRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: TRXM5_ORYSJ
Sequence: MALETCFRAWATLHAPQPPSSGGSRDRLLLSGAGSSQSKPRLSVASPSPLRPASRFACQCSNVVDEVVVADEKNWDSMVLGSEAPVLVEFWAPWCGPCRMIAPVIDELAKEYVGKIKCCKVNTDDSPNIATNYGIRSIPTVLMFKNGEKKESVIGAVPKTTLATIIDKYVSS
What is the function of this protein?
Thiol-disulfide oxidoreductase probably involved in the redox regulation of chloroplastic enzymes.  Required for chloroplast biogenesis and differentiation.  Functions as an electron donor for plastidial 2-Cys peroxiredoxins and participates in hydrogen peroxide scavenging system in chloroplasts.  Possesses reducing activity towards insulin disulfide bonds.
What are the official names of this protein?
Thioredoxin M5, chloroplastic, OsTrxm5.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant M-type subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNMA_SYNY3
Sequence: MTQKVVVGLSGGVDSSVAAALLHRQGYAVVGVTLWLMKGKGQCCSEGLVDAASICEQLGVPHEIVDTRDLFQNHIIDYLVQGYGEGVTPLPCSQCNKAVKFGPMLQYAQQSLGIDKIATGHYARIRFNEASQRYELLRAVDRQKDQSYFLYDLSQEILAATLFPLGEQTKTVTRQLAAEFDLSTAEKKDSQDLCLIEAHGSMRDFLDKYIAPKAGEIVDLSGAVLGHHEGIHHYTIGQRKGLGIAAAEPLYVVKLDPVMNRVIVGDRQSAGSGECYVQRLNWVSIPEPTAPIRCEVQVRYRSAPVTVNAIPWHDQQIKLVFDEPQFGITPGQAAVLYDGDRVLGGGIICPQKSETAGV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_MYCSS
Sequence: MASYAIVKTGGKQYKVAVGDVVKVEKLDSEPGASVSLPVALVVDGANVTSKAEDLAKVAVTGEVLEHTKGPKIRIHKFKNKTGYHKRQGHRQQLTVLKVTGIK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL1_MYCLE
Sequence: MSKSSKAYRAAAVKVDRTNLYTPLQAAKLAKETSSTRQDATVEVAIRLGVDSRKADQMVRGTVNLPHGTGKTARVAVFAVGEKADVAVAAGADVVGSDDLIEKIQGGWLEFDAAVATPDQMAKVGRIARVLGPRGLMPNPKTGTVTPDVAKAVADIKGGKINFRVDKQANLHFVIGKASFDEKRLAENYGAALEEVLRLKPSSSKGRYLKKVTVSTTMGPGIPVDPSITRNFTEE
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YQGF_LACH4
Sequence: MRLLGLDIGSKTVGVSVSDELGITAQKLETIKIDETKYNFGMRPLKKLVRQYEVDGFVLGLPKNMDGTSGASVARSKAYGKRLEEKFGLPVHYSDERLTTIESRRVLVEDAGIHDRKKRKQVIDQMAAVLILQNYLDLHRKD
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_PARDP
Sequence: MFAVLKTGGKQYRVQAGDVLRVEKLNAEAGDKVQFNDVLMIGSAVGAPLVAGAAVQAEVIDTIKADKVITYVKRRRKHSSQRTRGHRQQLTLVRITDLLEKGGDKSGVKPAVGARTKIEPAVKPAKAKKSEAEASAEDAN
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CESA3_ARATH
Sequence: MESEGETAGKPMKNIVPQTCQICSDNVGKTVDGDRFVACDICSFPVCRPCYEYERKDGNQSCPQCKTRYKRLKGSPAIPGDKDEDGLADEGTVEFNYPQKEKISERMLGWHLTRGKGEEMGEPQYDKEVSHNHLPRLTSRQDTSGEFSAASPERLSVSSTIAGGKRLPYSSDVNQSPNRRIVDPVGLGNVAWKERVDGWKMKQEKNTGPVSTQAASERGGVDIDASTDILADEALLNDEARQPLSRKVSIPSSRINPYRMVIMLRLVILCLFLHYRITNPVPNAFALWLVSVICEIWFALSWILDQFPKWFPVNRETYLDRLALRYDREGEPSQLAAVDIFVSTVDPLKEPPLVTANTVLSILAVDYPVDKVSCYVSDDGAAMLSFESLAETSEFARKWVPFCKKYSIEPRAPEWYFAAKIDYLKDKVQTSFVKDRRAMKREYEEFKIRINALVSKALKCPEEGWVMQDGTPWPGNNTRDHPGMIQVFLGQNGGLDAEGNELPRLVYVSREKRPGFQHHKKAGAMNALVRVSAVLTNGPFILNLDCDHYINNSKALREAMCFLMDPNLGKQVCYVQFPQRFDGIDKNDRYANRNTVFFDINLRGLDGIQGPVYVGTGCVFNRTALYGYEPPIKVKHKKPSLLSKLCGGSRKKNSKAKKESDKKKSGRHTDSTVPVFNLDDIEEGVEGAGFDDEKALLMSQMSLEKRFGQSAVFVASTLMENGGVPPSATPENLLKEAIHVISCGYEDKSDWGMEIGWIYGSVTEDILTGFKMHARGWRSIYCMPKLPAFKGSAPINLSDRLNQVLRWALGSVEILFSRHCPIWYGYNGRLKFLERFAYVNTTIYPITSIPLLMYCTLPAVCLFTNQFIIPQISNIASIWFLSLFLSIFATGILEMRWSGVGIDEWWRNEQFWVIGGVSAHLFAVFQGILKVLAGIDTNFTVTSKASDEDGDFAELYLFKWTTLLIPPTTLLIVNLVGVVAGVSYAINSGYQSWGPLFGKLFFAFWVIVHLYPFLKGLMGRQNRTPTIVVVWSVLLASIFSLLWVRIDPFTSRVTGPDILECGINC
What is the function of this protein?
Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation.  Involved in the primary cell wall formation, especially in roots.
What are the official names of this protein?
Cellulose synthase A catalytic subunit 3 [UDP-forming], AtCesA3, Constitutive expression of VSP1 protein 1, Isoxaben-resistant protein 1, Ath-B, Protein ECTOPIC LIGNIN 1, Protein RADIALLY SWOLLEN 5, AtRSW5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL29_GEMAT
Sequence: MKAEEIRGLADDELVARVLELEEERFRLRFRSGTEALEEPLRLRSIRRDIARLKTVQRERQLAARGR
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: VOLK_ADEVO
Sequence: VFPKVPFDVPKATVESYTRFIRVLRDELAGGVSPQGIRRLRNPAEIQPSQGFILIQLTGYVGSVTLIMDVRNAYLLGYLSHNVLYHFNDVSASSIASVFPDAQRRQLPFGGGYPSMRNYAPERDQIDHGIVELAYAVDRLYYSQNNNQIALGLVICAGMVAEASRFRYIEGLVRQSIVGPGDYRTFRPDALMYSIVTQWQTLSERIQGSFNGAFQPVQLGYASDPFYWDNVAQAITRLSLMLFVCSQPPRQSDSPLVIRSFVDRNDPVCPSGETTAFIVGRDGRCVDVKVEEFFDGNKVQMWPCKSSQNANQLWTLKRDGTIRCQGKCLTVRSPQLYAMIWDCTTFYAPATKWEVWDNGTIINPASGRVLTAPTGEAGVTLNLQFNEYAASQAWRVTNVTVPTVTTIVGYDDLCLETNGNGVWLANCVKGKAQQRWTLYADGTIRSQSTLSKCLACSGSCVKLAKIVNTDCAGSANSRWYFDNYGGIVNLRTGMVMDVKESNPSLNEIIAHPWHGNSNQQWFL
What is the function of this protein?
Binds to cell receptors and probably facilitates the entry into the cell of the A chain (By similarity).  Acts also as a galactose-specific lectin responsible for cell agglutination (PubMed:3932357, PubMed:16997573).
What are the official names of this protein?
Volkensin.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the ribosome-inactivating protein family. Type 2 RIP subfamily.
Protein: ATPA_LEUCK
Sequence: MAIQAEEISALIKQQLEKFDTTLTVEEVGTVTYIGDGVARATGLANAMAGELLEFANGTFGMAQNLESSEVGIIILGGFDDIREGDTVKRTGRIMEVPVGEQLIGRVVNALGQPIDGLGEIKTDKFRPVEVKAPGVMQRKSVFEPLQTGIKAIDALVPIGRGQRELIIGDRKTGKTSLAIDTILNQKDQNMIVIYVAIGQKDSTVRTQVETLRQMGAMDYTIVVNAGPSEPAPMLYLAPYVGAAMGEEFMYNGKHVLIVYDDLSKQATAYRELSLILRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNVISITDGQVFLDADQFYAGVRPAIDAGTSVSRVGGDAQIKAMKKVAGTLRLDLASFRELESFAQFGSDLDAATQAKLARGRRTVEVLKQPLHKPMPVQHQVIVLYALTHGYIDDIAVEDIQRFQDELIAYVDANANDLFKVIIDTKQLPEESAMNAAIEAFKAGFAGSAAE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNFE_SHESA
Sequence: MTNYREIAWQGLWKNNPGLVQLLGLCPLLAVTATLTNALGLGVATMLVLIGSNILVSLVRDYVPKEIRIPVFVMIIAALVTAVQLLINAYAYGLYLSLGIFLPLIVTNCIIIGRAEAFASRNNAFSAAFDGLMMGLGFTLVLAVLGATREILGQGTLFDGADQLLGPWAKALTIQVWQVDTPFLLAMLPPGAFIVMGLLIALKNVIDKKLKERQPEVAVQPSVTRARITKVS
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARSC1_STAHJ
Sequence: MDKKTIYFICSGNSCRSQMAEGWGKEILGEDWNVYSAGIETHGVNPKAIEAMKEVDIDISNHTSDLIDSDILEQSDLVVTLCSDADDNCPILPPNVKKEHWGFDDPAGKEWPEFQRVRDEIGKRIQEFKETLV
What is the function of this protein?
Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase 1.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX3_PISOC
Sequence: MTHQHPYHLVDQSPWPLTGAISALMMTSGLILWFHINSTILFILGTVLLVLTIINWWRDIIREATFQGFHTLSVSNGLRYGMILFITSEVCLFFAFFWAFFHSSLAPTIELGVSWPPTGITPINPFLVPLLNTAVLLSSGVTVTWAHHSILSGNRVEAIQSLTLTVFLGVYFTILQAWEYFDSPFTIADSVYGSTFFVATGFHGLHVLIGTAFLAVCLLRLYNFHFSNHHHFGFEAASWYWHFVDVVWLFLYICIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS8_MYCAP
Sequence: MFITDPISDMIVRIKNANQRKFKTVLIPYSNKKAKILEILLNEGYISSFVTKGEGKDKTLEVALKYKGNQSAIIDFKRISKPGLRVYAAANNLSSVLSGYGTVIISTSKGVMTEKQARKENVGGEVLAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL4_XANAC
Sequence: MELVITGSNNKVSVSDAVFGREFSEDLVHQVVVAYRNAGRAGTKAQKTRSEVAGTTKKSKKQKGGGARHGALTAPIFVGGGVTFAAKPRSFEQKVNRKMYRAAICAIFSELNRQGRLMIVDAFDLEATKTKGLIEKLKGLEVGKRPLIVTEEASEHLYLSARNLPYVQVRDVQGLDPVALVGADTVVITADAVKKVEEWLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RECQ4_HUMAN
Sequence: MERLRDVRERLQAWERAFRRQRGRRPSQDDVEAAPEETRALYREYRTLKRTTGQAGGGLRSSESLPAAAEEAPEPRCWGPHLNRAATKSPQSTPGRSRQGSVPDYGQRLKANLKGTLQAGPALGRRPWPLGRASSKASTPKPPGTGPVPSFAEKVSDEPPQLPEPQPRPGRLQHLQASLSQRLGSLDPGWLQRCHSEVPDFLGAPKACRPDLGSEESQLLIPGESAVLGPGAGSQGPEASAFQEVSIRVGSPQPSSSGGEKRRWNEEPWESPAQVQQESSQAGPPSEGAGAVAVEEDPPGEPVQAQPPQPCSSPSNPRYHGLSPSSQARAGKAEGTAPLHIFPRLARHDRGNYVRLNMKQKHYVRGRALRSRLLRKQAWKQKWRKKGECFGGGGATVTTKESCFLNEQFDHWAAQCPRPASEEDTDAVGPEPLVPSPQPVPEVPSLDPTVLPLYSLGPSGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPLLSLMDDQVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHADSTDFLAVKRLVQRVFPACTCTCTRPPSEQEGAVGGERPVPKYPPQEAEQLSHQAAPGPRRVCMGHERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELLATTYTHCRLNCPGGPAQLQALAHRCPPLAVCLAQQLPEDPGQGSSSVEFDMVKLVDSMGWELASVRRALCQLQWDHEPRTGVRRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQALARLRRTFQAFHSVAFPSCGPCLEQQDEERSTRLKDLLGRYFEEEEGQEPGGMEDAQGPEPGQARLQDWEDQVRCDIRQFLSLRPEEKFSSRAVARIFHGIGSPCYPAQVYGQDRRFWRKYLHLSFHALVGLATEELLQVAR
What is the function of this protein?
DNA-dependent ATPase.  May modulate chromosome segregation.
What are the official names of this protein?
ATP-dependent DNA helicase Q4, DNA helicase, RecQ-like type 4, RecQ4, RTS, RecQ protein-like 4.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecQ subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PTH_PECAS
Sequence: MSSIKLIVGLANPGAEYAATRHNAGAWFVDRLAESYRQSLKEESKFFGYTSRLNLAGQDVRLLVPTTFMNLSGKAVAAMATFYRIQPDEILVAHDELDLLPGIAKLKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKSKVTGFVLGKPPMSEQTLIDEAIDEAVRCTEILMKEDMIKAMNRLHAFKAA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_PARL1
Sequence: MQVVLLERVEKLGQMGDVVKVKDGFARNFLLPRKKALRATKANIERFEGQRAQLEARNLELKKEAEQVHTKVHGQSFIILRQAGETGILYGSVSTRDIATAMTDGGFTAARNQVVLDKPIKTIGLHDVRIVLHPEVSATIAINVARTQEEAERQAAGEDLTQRRDDEEEEAVEAAEFFESEELAPGDEEEEAAGEEEDAKE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PURQ_NITHX
Sequence: MKSAILVFPGINRERDMARALKLISGHEPAMVWHAETSLPKGTDLVVMPGGFSYGDYLRCGAIAARSPVMDAVRAFAADGGLVLGVCNGFQILCESGLLPGILMRNARLKFICHDVHLRVERSDTPFTRGYNAGQVIRVPVAHGEGNYAADEETIRRLEGEGRVLYRYCSATGEIGDTHNINGAAQSIAGIVNVRGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLERAA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_RIPO1
Sequence: MPLPKIEDARKLNDEELVEEILAAKRQLFTLRFQKATNRLEKTHEFKHTRHRLAQLMTVERERQLQAQSAPSVTPEEE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PININ_BOVIN
Sequence: MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERSTERPLFQDQNTDEKETPERPGPIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPAPKLIEESQRKTNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVVRNEEQKSEQEEGKVAPRTRVMLRALDDLVARVGTPSPRRGSGEEEEKEIPIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVESVKNVIAEQEVMETNQVERVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENASTLEMENEPEEKEEKESEPQPEPMAQPQAQSLPQPQPQRHRQSQSQPQQYSSPPPLSQPETLPLAVSQPPPQLIQRQGHLPPERKEFLVESVKLTEVPTEPVLTVHSESKYETKTRSRSRGRARNRTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRTSSSSSSTSGSSSRDSSSSTTSSSESRSRSRGRGHNRDRKHRRSVDRKRRDASGLERSHKSAKGGSSRDAKAVSSSGMPRFKPGQL
What is the function of this protein?
Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'.  Capable of reversing CTBP1-mediated transcription repression.  Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  Participates in the regulation of alternative pre-mRNA splicing.  Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites.  Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets.  Involved in the establishment and maintenance of epithelia cell-cell adhesion (By similarity).
What are the official names of this protein?
Pinin.
What is the protein family that this protein belongs to?
Belongs to the pinin family.
What are the subcellular locations of this protein?
Nucleus speckle. Cell junction, desmosome. Note=Cell-cell contact area, predominantly desmosome of intercellular adherens junction. Not a nucleocytoplasmic shuttling protein (By similarity).