PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_LACH4
Sequence: MIISKEVKLVVENEDAVTSGEVENSEEEAMELSLRPQTLDQYLGQKRVKKEMSIYIKAAKQRDEALDHVLLYGPPGLGKTTLAFVIANELGVHLKSTSGPAIEKAGDLVALLSDLDPGDVLFIDEIHRLAKPVEEVLYSAMEDYYIDIVIGEGQTTHAVHVPLPPFTLIGATTLAGQLSAPLRDRFGIVEHMQYYTIDELEKIVQRSSDVFHTSIAPEAAHELARRSRGTPRVANRFLKRVRDFAEVKGEKTISLATTEGALKQLQVDDEGLDQTDRRLLRTMIEGYNGGPVGIRTLAANVGEDMETIESLYEPYLLQHGFILLGPRGRMVTDKAYLQLGLPVPGDK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RNPS1_RAT
Sequence: MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGTTKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSSR
What is the function of this protein?
Part of pre- and post-splicing multiprotein mRNP complexes.  Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets.  The ASAP complex can inhibit RNA processing during in vitro splicing reactions.  The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis.  Enhances the formation of the ATP-dependent A complex of the spliceosome.  Involved in both constitutive splicing and, in association with SRP54 and TRA2B/SFRS10, in distinctive modulation of alternative splicing in a substrate-dependent manner.  Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function.  Participates in mRNA 3'-end cleavage.  Involved in UPF2-dependent nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Also mediates increase of mRNA abundance and translational efficiency.  Binds spliced mRNA 20-25 nt upstream of exon-exon junctions (By similarity).
What are the official names of this protein?
RNA-binding protein with serine-rich domain 1.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein. Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles (By similarity).
Protein: SELD_YERPE
Sequence: MASPAIRLTQYSHGAGCGCKISPKVLDKILHTEQQKFFDPRLLVGNETRDDAAVYDIGNGVGIISTTDFFMPIVDDPFDFGRIAATNAISDVYAMGGKPIMAIAILGWPIDKLAPEIAQQVIEGGRYVCQQAGISLAGGHSIDAPEPILGLAVTGIVSTEQVKKNSAAKPGCKLFLTKPLGIGILTTAEKKSKLRPEHRGLATETMCQLNKPGADFAHIPGVTAMTDVTGFGLLGHLSEICQGSGVQAILHYSAIPRLPAVEDYIAEGCVPGGTGRNFDSYGHLIGNMSDLQKQLLCDPQTSGGLLLAVLPDAEADVQAIAAQHGMTLSPIGELTSADSRRALIEIVV
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: ENGB_NEIM0
Sequence: MNLFQNAKFFTTVNHLKDLPDTPLEIAFVGRSNAGKSSAINTLTNHVRLAYVSKTPGRTQHINFFELQNGNFMVDLPGYGYAQVPEAVRAHWVNLLGDYLQQRKQLIGLVLIMDARHPLKELDIRMLDFFHTTGRPVHILLSKADKLSKNEQIKTLSQVKKLLKPYSDRQNISVQLFSSLKKQGIDEANRTVGSWFDAADAAASSPKEN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SYC_KOCRD
Sequence: MTLRFYDTASATIKDFVPVHPGEARLYYCGATVQGAPHIGHVRSALVFDVLARWLRFRGLEVTTVRNVTDIDDKILVNSRASYEQDYSGDHAREPWWALAYRFEGVFGQAYAALGIDRPTYEPRATGHVPEMHALIQELIDAGHAYPATDGSGDVYFDVRSWPRYGELTRQRVEDMQDAPDADPRGKRDPRDFALWKGRKEDEPLSASWDSPWGRGRPGWHLECSAMAGKYLGAHFDIHGGGLDLRFPHHENELAQSTAAGREFANFWLHNGLVTYEGEKMSKSIGNTVSPQDMLREARPLAVRYYLGQAHYRSVLDYRPTSLQEATAAVERVEAVLVAARAAGLGLDRDTQDVPAEFVAVMDDDLNVPRALAVLHETVRAANSALATGDHDAARPLVAAVAGMSDVLGLLQLMDLEGAGAGGAEHRALDVLVQDLLAQRAAARTARDWASADRIRDQLAAAGVVVKDGAQGSAWSVES
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_STAAM
Sequence: MARSIKKGPFVDEHLMKKVEAQEGSEKKQVIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTFKGHVADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: EURL_CHICK
Sequence: MNEEQFVNIDLDDDNVCSVCKLGTEKETLSFCHICFELNIEGVPKSDLLHTRSLRGHRDCFEKFHLIANQDCPRTKLSRSPYAEVKSILSKKINWIIQYAQNKDIDSDTESSKTSQHPLFNLRHQTDRKLLPQFDSPVPRYSAKWIDGNSGSISNCSQSLLEQSEPTDFRLGMLQETGATFCCSSVLWSNRSQAQKTEKAESDSLTSPHRRHPHYSREELNMMTTGELKQLNEKLLKQIQDVFEELTQQVQEKDSLASELNVRHIAIEQLLKNCSKLPCLQMGRAGMKSNVPI
What is the function of this protein?
Plays a role in cortical progenitor cell proliferation and differentiation.  May promote dendritic spine development of post-migratory cortical projection neurons by modulating the beta-catenin signaling pathway.
What are the official names of this protein?
Protein EURL, Early undifferentiated retina and lens protein.
What is the protein family that this protein belongs to?
Belongs to the EURL family.
Protein: NDHH_CRYJA
Sequence: MIMVAREKDLMMVSMGPHHPSMHGVLRLIVTLDGEDVIDCEPVLGYLHRGMEKIAENRTIVQYLPYVTRWDYLATMFTEAITVNAPEKLENIQIPKRASYIRMIMLELSRIASHLLWLGPFMADIGAQTPFFYILREREMIYDLFEAATGMRMMHNYFRIGGVAVDLPYGWIDKCLDFCYYFFPKVTEYERLITRNPIFLKRVEGVGIISREEAIDWSLSGPMLRASGIQWDLRKVDHYECYDELDWEIQWQKEGDSLARYLLRIGEMKESIKIIRQALEVIPGGPYENLEVRRLNKGKDSQWNDFESRFISKKPSPTFELSKQEHYVRVEAPKGELGIFFIGDDNIFPWRWKIRPPGFINLQIPPQLVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: YQGF_NOSS1
Sequence: MTKYISALGLDVGRKRVGVAGCDRTGLIATGITTVERTSFDRDVQQIQNIVNERQVQVLVVGLPYSMDGSLGFQARQVQKFTSRLAKALQLPVEYVDERLTSFQAEQMLIAENVSPSRNKGLIDRKAAALILQQWLDIRRTNAQSSVAVEY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H6ST3_HUMAN
Sequence: MDERFNKWLLTPVLTLLFVVIMYQYVSPSCTSSCTNFGEQPRAGEAGPPAVPGPARRAQAPPEEWERRPQLPPPPRGPPEGPRGAAAPEEEDEEPGDPREGEEEEEEDEPDPEAPENGSLPRFVPRFNFSLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVEINEGARQRIEDLNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERRLQREHRDHQWPKEDGAAEGTVTEDYNSQVVRW
What is the function of this protein?
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
What are the official names of this protein?
Heparan-sulfate 6-O-sulfotransferase 3, HS6ST-3.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: T2R42_MACMU
Sequence: MATEMDKIFLTLATVEFIIGMLGNVFIGLVNCSEGIKNQKVFSVDFILTCLAISTIGHLLVILFDSCVVGLAPHLYATDRVRRPVTMLWHMXNHLTTWLATCLSIFYFFKIAHFPHSLFLWLRWRMNRVIAILLTLSLFLLIFDCLVLEMFIDXSLNIIDKSNLTLYLDESKTPYDKLSLLKILLSLNSFIPFSLCLTSLLFLFLSLVRHTRNLKLSSLGSRDSSTEAHRRAMKMVMSLLFLFIVHFFSLQVANWTFCILGNNKYTQFVTLALHAFPSCHSFILILGNSKLRQTAVRLLWHLRNYTKRPNPLPL
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 42, T2R42, T2R55.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y836_METJA
Sequence: MIELAKNHLKKVLEVCGANRNCEYYPCHFDGQVCLWCYCPFYPCEDEELGEYVEKKDGTKIWSCMKCFWVHREDVATEILREILNLTKDKDIDEALKLLDNHELMLKIKDRVKAKYPNR
What are the official names of this protein?
Uncharacterized protein MJ0836.
Protein: Y2808_BORPE
Sequence: MTTTTSTLPLPTPWRDKLNGILFVALMAAAVVQLADLPFIRQFGFSPLVVGIVCGMLYGNFLRGTMPADWGAGVHFTARRLLRIAVAFYGLNISIQQIAAVGLPGLAVSVGVVASTLLIGTVAGQRLLGLDRDTAMLTAAGSAICGAAAVLAFEPTLRAAPHKSAVAVATVVLFGTLSMFLYPVIYHAGWLPFDTQALGIYIGGTVHEVAQVVGAASNIDPATTEVATIVKMTRVALLVPVLLVLGFWLRASAAAGADGKSHAKLPVPWFAIGFLVLAIVNSLDILPSDLVTAIRKLDVFVLTMAMTALGIETRFAQIRKAGPRVMALGLVLYAWLVFGGYGIVKLAT
What are the official names of this protein?
UPF0324 membrane protein BP2808.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOA_CALBD
Sequence: MIEFQKPTIRCEELSPDNKYGRYVIEPLERGYGITVGNALRRTLLSSLPGAAVTAVKIDGVLHEFSTIPGVLEDVPEIILNLKGLAIKMSSPGPKVMYIEAQGECEVKAKDIKADADIEICNPDHHIATLNQDARLFMEITVNQGKGYVLAERNKQPNQPIGVIPVDSIYTPVVKVNYKVENTRVGQVTDYDKLTMEIWTNGTIRPDEALTVAAKILIEHFNLFTDLSNIPTKIETVVKQEPPKRNKLLDMTIEELELSVRSYNCLKRAGINTVEDLVNKTEEEMMKVRNLGKKSLEEVIQKLHSLGLSLKKSDSTPKEEEEEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: BRIX_METBU
Sequence: MLITSSRKPSANTRTMCKYLASFFNCKYMTRGKMGLIDIVSLCENGLLMVVGDYHGSPGSIMFYDSHGVELLSIHLSVFYPDGYKYTPLKALEPSINGDGELFNLLSYYLDIPEGECYYDSKCLIASDDHLEFVYLDNMLFRLNIKNYRKMVMSE
What is the function of this protein?
Probably involved in the biogenesis of the ribosome.
What are the official names of this protein?
Probable Brix domain-containing ribosomal biogenesis protein.
Protein: LSRF_ECOHS
Sequence: MADLDDIKDGKDFRTDQPQQNIPFTLKGCGALDWGMQSRLSRIFNPKTGNTVMLAFDHGYFQGPTTGLERIDINIAPLFEHADVLMCTRGILRSVVPPATNKPVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLVDAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGAQIIKTYYVEKGFERIVAGCPVPIVIAGGKKLPEREALEMCWQAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHNETADRAYELYLSEKQ
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.
What are the official names of this protein?
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDH16_ARATH
Sequence: MTRRRHGWQRPLHPLQIVGAVIYSVLVAAFYVFLGFFLGNRIAVIALLSVFSSVAVSVIVLFVRCTAIDPTDKTSAKKKRKDKSKGVLMKLRVKVVLSQVVVRFFRRLERKILRNFLRRTYLDPWKSSVQLEPLLPFPLVMKDDDSVTPDPKEEDDISYCSLCDLEVKRSSKHCRTCNRCVEGFDHHCRWLNNCVGKKNYTTFILLMVFVLLMLIIEGGTALAVFVRCFVDKKGMEMELKRRLYVEFPQWALATISIILVLFTAYGSAAMGQLFLFHVVLIRKGMRTYDYILAMKEENQFTEVDPFDELDSSSDESSDFDSPERLRPTFISKFMCRKANENQQRLSIKIEGDEQSPSSTLINKKPGFHVSINPWKLITLSSEKALQAAEKAKERLRKTKPVSGTEENSLKPLPLETKFGLLLDPDNNNTVLQPSTTAAVKLQVSPGRFSSPRRRFSGSSSSTVPSPKQKYRTNFDLKLTEVSRELESYISRQVLCSVIKQDGSEASPR
What is the function of this protein?
S-acyltransferase involved in protein lipid modification.
What are the official names of this protein?
Protein S-acyltransferase 18, Probable palmitoyltransferase At4g01730, Zinc finger DHHC domain-containing protein At4g01730.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: URED1_METEP
Sequence: MALSLDGLPEKPAPAEAPSPPVGRRVQASLVFARGGRTTVLSRQVVPYPFHITRAFRMHPESPDLATLYLQSASGGLYAADHLTLAIAARAGARAHVTTQAGTVVHRGGPEPSRQETRLTIAADAFLALNPDPLILFPGAHLAVSTEITAEPGARAIVTESVACHDPVGEGRPFDRLDLGLTIRDPEGRALVRERSRIDGRAFTAPDSPMGPHRAYGTMVVLGAPDDARLAGLHLRQAADAAGCLTGVSPLPNGAGLGLRLLAPDGGTLSAGMDAVFRIVFETLSGCAPGRRRK
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 1.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_COFAR
Sequence: MIFSTVEHILTHISFSIVSIIITMRLISFFLVDGIVQLYDSSEKGMIVTFLCLTGLLVTRWTYSGHFPLSNLYESLIFLSWSFSLIHIVPYFKKNKKYLSTITGSSVVFTQGFTTSGLLTEIDQSSILVPALQSEWLIMHVTMMILGYASLLCGSLLSIALLVITFRKNKKILYRNNLLLNESFFFVEIEYMNERSNLLQNTSFFSAKNYYRSQLIQQLDYWSSRGISLGFIFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWIIFAIYLHTRTTRNPKCANSAIVASIGFLIIWICYFGVNLLGIGLHSYGSFTLLAN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y3148_CROS8
Sequence: MDKYCELIRQRYSQIASGELGYIPDALGCVLRALNEVASDEALSESVREQAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein ESA_03148.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: RLMM_ALCBS
Sequence: MHSDLLNSQSETLLALCRPGFEADLAAELNFHAADQMVAGYPRATANSGYVLWHSQQGSLASLQESGLIFARTLSVCEGEFSDIGDDRISALWPLLEAAGPFSELYLEHPDTNEGRELQRFLRGFRKALEPRLKKVGLLRRQAKQRLHLFFSDSHNGWVGTSPSAVPLVEGGVLRLRLPAEAPSRSALKVEEALIRFFGSADALNAKTAVDLGAAPGGWSWQLARRGIRVQAVDHGKMAPRLLDEYPVQHVYGDAFTWRPRSKVDLVVCDVVDKPARTLQHMEKWLTQGWATAALFNLKLPMKRRFQETWQLLEKLTAAMERMDHLGEPVIKAAHLYYDREEITVWASFHRSY
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNPF_LOCMI
Sequence: SNRSPSLRLRF
What are the official names of this protein?
Short neuropeptide F, Lom-sNPF, sNPF.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: UXAC_BACVZ
Sequence: MKAFMGDDFLLNSKTAVKLYREYAENMPIIDYHCHLSPKEIYENKTFATITEAWLYGDHYKWRIMRANGIEERCITGNASDEEKFFAWAKTVPMAIGNPLYSWTHLELQRWFGIYDVLNEKTAAAIWKKTNELLQGDGFGARDLILKSNVKVICTTDDPADALTYHELLKESDFPVQVLPGFRPDKGLDISSPGFADWVRSLESASGMAVSSYQSYLDALESRVRFFHNAGGRVSDHALDQMVYAETTEEEAARIFAAGLSGEHVSFEDEKKFKTRTLQYLCGLYAELDWAMQFHINALRNTNTNKFSSLGPDTGYDSINDERIAKPLARLLDSAEKKRQLPKTILYSLNPNDNYIIASMINSFQDGKTPGKIQFGTAWWFNDTKDGMLQQMRALSNMGLFSRFIGMLTDSRSFLSYPRHEYFRRLVCTLIGGWAEQGEAPYDMELLGKIVEGICYRNAEEYFRF
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: YQEH_SCHPO
Sequence: MNDTNDVMHVHSESISPKKNDLDIELGESVVEPHLSNNSIAKLDTYELEENEDISDYAYKLAGISNEHPAHPQNWGWWKKAYIVLLSTSLQMYVFWTPNFYPGVQDSVMELWHLSSQVSLLGQSMFVLGVALGPLFLGPLSDLLGRKLVYIGSLIIYVCFCISCALARNYAQLVISMLIMGVVGSTALGNVAGAVADVLGDEDSNWGMYMFIFMCSVASVGSPMGTGVAENPKLTWRWLYWIDVIVGGFFIILFVFTPETLPAIVIQRYEQKRQGLPVSWFPQFSLKKLAKDTYFVFFMAIKIFFSEPIVSSLGIYNGFVNGLLYFFLQAIWPVYFSIYKMSDMAASCTYMAAMPACVILLWFEPLQCWLYKRDKRKHQNRLRPEARFIMTLFYVWGFPIGIFMFAFCSKVHIHYIVSLIGLTIFNIADYHIWQAMLLYVTDAYPNVSASAVAAFELPSNLGAVGFIHLSALMFSRMNVHWATAVVGFASLPLIALIYALYFYGDRIRARSKLASQRVPINTAAH
What are the official names of this protein?
Uncharacterized transporter C576.17c.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: THIE_YERPE
Sequence: MATPGFPSTEQRLGLYPVVDSLLWIERLLAAGVTTLQLRIKNADDAQVEQDIVAAIELGKRYQARLFINDYWQLAVKHGAYGVHLGQEDLEAADLAAIQQAGLRLGISTHDEHELAVAKTLRPSYIALGHIFPTQTKQMPSSPQGLASLSRQVKNTPDYPTVAIGGISIERVPHVLATGVGSVAVVSAITLASDWQRATAQLLHLIEGKELADEK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: DEFI_PYRAP
Sequence: ATCDILSFQSQWVTPNHAGCALHCVIKGYKGGQCKITVCHCRR
What is the function of this protein?
Antibacterial peptide.  Affects Gram-positive bacteria M. luteus, B. megaterium, A. viridans, S. aureus and S. saprophyticus.  Moderate activity against P. acidilactici and B. subtilis QB935.  Also affects Gram-negative bacterium, D22 form of E. coli.
What are the official names of this protein?
Defensin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VDTB1_BYSSP
Sequence: MPAYLLLLACNVLLVLGAHVQRELVLTWEEGAPNGQSRQMIKTNGQFPSPTLIFDEGDDVEIVVRNYMHENTTIHWHGILMQDTPWSDGVPGLSQKPIEPGESYVYRFTAYPPGQYWYHSHSRATLLDGLYGALFIRRKPGTAGPWAMISEDPEDIAAMERASNNPHIMMLSDWDYYNSTQYKEADANSRLQIFCVDSILLNGKGSVYCPGHQWLIDKQIPFMHKSWPNDTITDKGCFPFVPSTEGPWLADGNVSAIPPGLQEGCVPYSGPTEAIEVDPADRWASVNWIGGSTFKTLQPTIDEHEMWIYEVDGHYIEPRRADTFLIWAGERYSAMIRLDKKPMDYSIRVPDGGYSQMIAAFGILRYKNGDPNARQKPDRFGVTTISKPYFDYNAWPMRDAVFLDKLDLPPWPRKVPAAHGDDMHVLYLGKANSTWEFTLSGKKKYPPDRSAYEPLLYNVNSEQAHDDDLIIRTQNGTWQDIVLQVGHSPLWPVDFPHAVHKHANKYWRIGGGQGLWNYSSVEEAMADQPESFNMVNPPYRDTFLTEFTGAMWVVLRYQVTSPGAWLLHCHFEMHLDNGMAMAILDGVDKWPHVPPEYTQGFHGFREHELPGPAGFWGLVSKILRPESLVWAGGAAVVLLSLFIGGLWRLWQRRMQGTYYVLSQEDERDRFSMDKEAWKSEETKRM
What is the function of this protein?
Multicopper oxidase; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity (PubMed:31304040, PubMed:31045362).  The first step is performed by the polyketide synthase VdtA which condenses one acetyl-CoA and 6 malonyl-CoA units to form the heptaketide monomer backbone of viriditoxin (PubMed:31304040).  The product of VdtA is then O-methylated on C7 by the O-methyltransferase VdtC (PubMed:31304040, PubMed:31045362).  The O-methyl group is important for the stereoselective coupling of the monomers at the final step of viriditoxin biosynthesis (PubMed:31304040, PubMed:31045362).  The short-chain dehydrogenase/reductase VdtF then acts as a stereospecific reductase converting the pyrone to dihydropyrone via the reduction of the C3-C4 double bond (PubMed:31304040, PubMed:31045362).  The FAD-binding monooxygenase VdtE then converts the ketone group into a methyl-ester group to yield semi-viriditoxin (PubMed:31304040, PubMed:31045362).  Finally, the laccase VdtB is involved in dimerization of 2 semi-viriditoxin molecules to yield the final viriditoxin (PubMed:31304040, PubMed:31045362).  VdtB is responsible for the regioselective 6,6'-coupling of semi-viriditoxin, which yields (M)-viriditoxin and (P)-viriditoxin at a ratio of 1:2 (PubMed:31304040, PubMed:31045362).  The non-catalytic carboxylesterase-like protein VdtD affects the stereochemistical outcome of the coupling (PubMed:31304040, PubMed:31045362).  The highly reducing polyketide synthase VdtX is not involved in viriditoxin synthesis, but might possibly play a role in the production of additional metabolites not identified yet (PubMed:31304040, PubMed:31045362).
What are the official names of this protein?
Multicopper oxidase VdtB, Laccase vdtA, Viriditoxin biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.