PharMolix/UniProtQA huggingface dataset:
Protein: RL33_MICLC
Sequence: MAKDKDVRPIIKLKSTAGTGFTYVTRKNRRNNPDRITLKKYDPVVRKHVDFREER
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TRUB_BUCAP
Sequence: MFFHKKRNVNGFLLLDKPKGMTSNNVLQKVKIIFKAKKAGYIGTLDPLATGILPICFGEATKFSNYLNASDKHYNVIARLGEKTSTSDSDGIIVRKRPILFTPIQLSLALKALTGSVNQIPSMYSAVKYKGIPLYKYARQGINVKRNIRCVFIYKIDLVDQKDNWIELNVHCSKGTYIRTLIEDLGEKLFCGAHVIRLRRLKIGLLSYSKLVKLSFLENLLNEKNVVKINFFKKIDDLLMPVDTPVYFLPKIYISIEKLSVFRLGQKVNFSSSITNGLVRVFEKDNNTFIGLGKINSEKTLIPYRLVSMLTN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: GUAA_CANGA
Sequence: MSSIEQVNEVFDTILVLDFGSQYSHLITRRLREFNIYAEMLPCTQKIADLHFKPKGVIMSGGPYSVYAEDAPHVDHAIFDLGVPILGICYGMQELAWINGKQVARGEKREYGPATLNVLDKEDALFKNVDHSTVWMSHGDKLHGLPTGFKVIATSDNSPYCGIVHESKQIYGIQFHPEVTHSSNGKTLLKNFAVDLCHAKQNWTMKNFIGTEVQRIRDLVGPTAEVIGAVSGGVDSTVASKLMTEAIGDRFHAILVDNGVLRLNEAATVKKTLVDGLGINLTVVDAADEFLDNLKGVTDPEKKRKIIGNTFIHVFEREAEKIKPKDGKAIEFLLQGTLYPDVIESISFKGPSQTIKTHHNVGGLLENMKLKLIEPLRELFKDEVRELGELLGISHELVWRHPFPGPGIAIRVLGEVTREQVEIARKADHIYIEEIRKAGLYDKISQAFACLLPVKSVGVMGDQRTYEQVIALRAIETTDFMTADWYPFEHSFLRKVASRIVNEVDGVARVTYDITSKPPATVEWE
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBC_NEPOL
Sequence: MKNLYSLRRFYHVETLFNGTLIVGGRDQESTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGYGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGVYHSLIGPETLEESFPFFGYVWKDKNKMTTILGIHLVLLGLGALLLVLKARYLGGVYDTWAPGGGDVRVITNPTTSPAVIFGYILKSPFGGEGWIVSVDNMEDVIGGHLWIGLLCVFGGIWHILTKPFGWARRAFVWSGEAYLSYSLGAISVMGFIACCFVWFNNTVYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEIIFGGETMRFWDTRAPWIEPLRGPNGLDLSKLKNDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNFVSPRSWLSTSHFVLGFFFFVAHLWHAGRARAAAAGFEKGIDRDTEPTLFMRPLD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL36_CHESB
Sequence: MKIRNSLKALKGRHRENRMVRRKGRIYIINKSNPRYKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: APT_STRGC
Sequence: MNLKDYIATIENYPKEGVTFRDISPLMADGNAYSYAVREIVQYATDKKIDMVVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIERLGGIVAGCAFLIELDELKGREVIGEYDYKVLMHY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_VIBCH
Sequence: MAGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLTISEADLQVDLDRRRPGTSRYTTQRREPDEVKILSGVFEGKTTGTSIGLLIENTDQRSKDYSDIKDKFRPGHADYTYHQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLQQEFGIEVRAYLSQMGEVAIDKVDWNEIENNDFFCPDVDKVAAFDELIRELKKEGDSIGAKIQVVATGVPVGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVRQKGSQHRDPLTPQGFRSNHSGGILGGISSGQDIVANIALKPTSSITVPGETIDVNGEPTELITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRGQNQGVVTTTPKI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: XYL1_CANPA
Sequence: MSTATASPAVKLNSGYEIPLVGFGCWKLTNDVASDQIYRAIKSGYRLFDGAEDYANEQEVGEGIKRAIKEGIVKREELFITSKLWNSFHDKKNVEVALMKTLSDLNLDYVDLFYIHFPIAQKPVPIEKKYPPGFYCGDGDKWSIEEVPLLDTWRALEKLVDQGLAKSIGISNFSAQLIYDLIRGCTIKPVALQIEHHPYLTQPKLVEYVQLHDIQITGYSSFGPQSFLEMDLKRALDTPVLLEEPTVKSIADKHGKSPAQVLLRYQTQRGIAVIPRSNSPDRMAQNLSVIDFELTQDDLQAIAELDCNLRFNEPWDFSNIPVFV
What is the function of this protein?
Reduces D-xylose into xylitol.  Preferentially utilizes NADH as a cosubstrate.
What are the official names of this protein?
NADH-dependent D-xylose reductase, XR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: RS12_SYNP2
Sequence: MPTIQQLIRSERYKLKKKTKSPALKQCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGTLDATGVKDRKQGRSKYGAKRPKE
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SELU_SHELP
Sequence: MDNHQLANVIPASEYGRILASGHPIMDVRAPIEFTKGAFPASSNHPLMRDDERQQVGTCYKEHGQDAAIALGHSLVCGAVKQQRVDAWLAYLDAHPDAYLYCFRGGLRSQLTQQWLAEAGRDVPYIQGGYKAMRQYLIDTIDRAPEARPMLILSGITGSGKTDFLLQRQEAVDLEGLAHHRGSSFGRYHEGQPTQINFENSLGVALLKHQQSPARILLLEDESYLIGRSALPKAFYMGMQAASVVILEEPLEARLTRLLDEYVHKMHRGYVERLGEEAGFEAFAEYLANSISGIKKRLGGKQHDELQQMITDALAVQTQRGDTQAHLEWIALLLSKYYDPMYQYQIGKKADRVIFQGDHQAMHQWLDEYATR
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: RL23_SULTO
Sequence: MIIKEFLTTEKAIKLIESQNTLTVIVNKEATKADIKREIEKMFNVKVDKVNTLITIRGEKKAYVKLKKEFNASDIAHRLGIL
What is the function of this protein?
Binds to 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: KDPC_METRJ
Sequence: MLKQLRPALVLLTALTAITGLAYPLAMTGLAGAIFPAKAAGSLIERDGTVIGSSLIGQNFTGAGYFHGRPSATTAPDPADASKTVPAPYNAANSSGSNLGPTSAALAERVKADVEALKSENPGAPVPVDLVTTSGSGLDPDISPEAAYFQVPRVAKARNIPQDKLRDLVTARIEGRTLGVLGEPRVNVLALNLAVDDLARR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CHED_OCEIH
Sequence: MTSIETTVVKVGIADLKIIQFPQLIRTSGLGSCVGTVIYDDKKEIAGLSHVLLPYSQQGKQANTNPYKYADTAISYLYNELLKRGANQSSLKAKLAGGAQMFQLRTGSDLMRIGPRNVESVELALAEFGIPIVSKDVGGNLGRTIEFDPRSKLLAVRKINQEVIMI
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: RS9_CHLL3
Sequence: MKEVIDTVGRRKTSVARVFMTPGKGRVIINKLPVEEYFRDEVKRLHALRPLVLTEKTEDFDIKVNVKGGGLSGQSGAVSLGIARALTEFDEAARAVLKQERLLTRDPRMVERKKFGRKKARKSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: YIDC_LEGPC
Sequence: MDIRRIVLYMALALIGLSLWNAWQIDYPAAQPVEDKTASQLTSDGHLLPQIIPSNAEQPVTLKAEEKASSGKQLIQVKTDVLDVGIDLKNGDIVKGLLLDYPLSVEDKNKPFPLLQNQASQRYVANSSLFVLDGQTPQSLDFDFTSEKEYYELKPDQNQLIVTLNGKSEDGLDVKKEFVFTKGSYLIEVNYKIANTGNSLWKGYFNTQLLRSSPKEDKSSIFHIGSYTGASFSNPGKNRYQKVSFSDMSKSNLDVDAKGGWIAMQQHYFLSAWVPNADSENKFYTLATDKDYTIGAVSQPITVKPKEDKIVGSKLYIGPEITSVLKGISPSLDLTVDYGILWFLSSLLFSLMKAIYTVVGNWGWSIVLVTVLIKLAFYRLSATSYKSMASMRKLQPKLQALRERYGDDKAKISQATMELYKQEKVNPLGGCLPILIQIPVFIALYWVLLESVELRQAPFIFWINDLASADPYHVLPLIMGATMLIQQKLNPAPADPMQAKVMMFLPILFTGLFWNFPSGLVLYWIVNNTLSILQQWYITRKYSDEKPAKKVVATAK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOR6_ARATH
Sequence: MKAVVSKLYCSSMEEVMVVRRRPHVVNGGGFVVTDYKEKIVFKIDGCGVLGTKGELVLRDSDGNDLLLIHKKGGVVQALSIHNKWKGYSYDYQGSPKPVFTLRDPKHSCFSITSSIRISVGPGNCYFDVKGYFPDRDCSIVDSKGNVIAQVKEWIGSRDIYKVVTKPSVDKAFVFGVIAVLDYIYGESTSC
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 6.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: CD8A_HUMAN
Sequence: MALPVTALLLPLALLLHAARPSQFRVSPLDRTWNLGETVELKCQVLLSNPTSGCSWLFQPRGAAASPTFLLYLSQNKPKAAEGLDTQRFSGKRLGDTFVLTLSDFRRENEGYYFCSALSNSIMYFSHFVPVFLPAKPTTTPAPRPPTPAPTIASQPLSLRPEACRPAAGGAVHTRGLDFACDIYIWAPLAGTCGVLLLSLVITLYCNHRNRRRVCKCPRPVVKSGDKPSLSARYV
What is the function of this protein?
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses.  In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex.  The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins.  Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs).  In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.  LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of cytotoxic T-lymphocytes (CTLs).  This mechanism enables CTLs to recognize and eliminate infected cells and tumor cells.  In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells.  CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Note=CD8A localizes to lipid rafts only when associated with its partner CD8B. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: MZM1_CANAL
Sequence: MSSVLSAYRNALRATKVAFRQDLPILQAARVQLKQGIRDNSNLQAQPEIEEAVQKLNEVAKFLIQNIVQGEKQQDGKYFLNFHEKTELGDNETIKQGRKEMGSLAGKKGSSIKSCND
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CAPSH_ASFK5
Sequence: MASGGAFCLIANDGKADKIILAQDLLNSRISNIKNVNKSYGKPDPEPTLSQIEETHMVHFNAHFKPYVPIGFEYNKVRPHTGTPTLGNKLTFGIPQYGDFFHDMVGHHILGACHSSWQDAPIQGSSQMGAHGQLQTFPRNGYDWDNQTPLEGAVYTLVDPFGRPIVPGTKNAYRNLVYYCEYPGERLYENVRFDVNGNSLDEYSSDVTTLVRKFCIPGDKMTGYKHLVGQEVSVEGTSGPLLCNVQDMHKPHQSKPILTDENDTQRTCTHTNPKFLSQHFPENSHNIQTAGKQDITPITDATYLDIRRNVHYSCNGPQTPKYYQPPLALWIKLRFWFNENVNLAIPSVSIPFGERFITIKLASQKDLVNEFPGLFIRQSRFIPGRPSRRNIRFKPWFIPGVISEISLTNNELYINNLFVTPEIHNLFVKRVRFSLIRVHKTQVTHTNNNHHDEKLMSALKWPIEYMFIGLKPTWNISDQNPHQHRDWHKFGHVVNAIMQPTHHAEVSFQDRDTALPDACSSISDISPITYPITLPIIKNISVTAHGINLIDKFPSKFCSSYIPFHYGGNSIKTPDDPGAMMITFALKPREEYQPSGHINVSRAREFYISWDTDYVGSITTADLVVSASAINFLLLQNGSAVLRYST
What is the function of this protein?
Capsid protein that self-assembles to form the pseudo-hexameric capsomers of the icosahedral capsid (By similarity).  The capsid is constructed of 2760 pseudo-hexameric capsomers and 12 pentameric capsomers, with a T=277 symmetry, about 200 nm in diameter (By similarity).  The capsid encapsulates the DNA-containing nucleoid, the core shell and the inner membrane (By similarity).  Plays an essential role in virion assembly (By similarity).  Involved in virus attachment to the host cell (By similarity).
What are the official names of this protein?
Major capsid protein, MCP, p72, p73.
What is the protein family that this protein belongs to?
Belongs to the NCLDV major capsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum membrane; Peripheral membrane protein. Host cytoplasm, host cytosol. Note=Present in the outer part of the capsid shell (By similarity). Localizes to the viral factory at 16 hpi (By similarity).
Protein: CLPP1_TREPA
Sequence: MRERMHNLVPYVIEQSGGGERSYDIFSRLLKDRIIFVDGEITDAVADLVVAQLLFLESQNPDKDISLYINSPGGAVTAGLAVYDTMQHICPEVQTICLGQASSMAAVLLAGGAPGKRFALPSSRVMIHQPWGGVQGQASDVCIQAQEILRLKTLTIAYFALHTGQSEEQVREDMERDFFLSAEQACSYGIVDTVMKRRKHAQV
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YICR_ECOBW
Sequence: MKNNSQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHRRLFSGTLNHVEVHPREIIREAIKINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: MIOX_ORYSJ
Sequence: MTITIEQPHLDAIADRKVAGGGGGDNAAELVLDGGFVVPDSNAFGNAFRNYEAESERKETVEEFYRVNHINQTYDFVRRMREEYGRVDKTEMGIWECIELLNEFIDDSDPDLDMPQIEHLLQTAEAIRKDFPDEDWLHLTGLIHDLGKVLLHPSFGELPQWSVVGDTFPVGCAFDECNVHFKYFKENPDYLNPKLNTKFGAYSEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYMHLMNDEDKENLKWLRVFNKYDLYSKSNERIDVEKVKPYYMSLIEKYFPAKLRW
What is the function of this protein?
Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers.  May be also involved in plant ascorbate biosynthesis (By similarity).
What are the official names of this protein?
Probable inositol oxygenase, Myo-inositol oxygenase, MI oxygenase.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADC1B_TOBAC
Sequence: MPALGCCVDAAVSPPPGYSFLWDSSLPAPEIFPSGVPLSTNTAATTTTTTHWSPAHSSALYSIDGWGAPYFTVNSSGDISVKPHGTETLPHQEIDLLKVVKKASDPKNSGGLGLQFPLVVRFPDILKNRLESLQSAFDYAVQSQGYEAHYQGVYPVKCNQDRFVVEDIVKFGSGFRFGLEAGSKPELLLAMSCLCKGSREGLLVCNGFKDADYISLALVARKLMLNTVIVLEQEEELDLVIDISRKMAVRPLIGLRAKLRTKHSGHFGSTSGEKGKFGLTTTQIVRVVKKLEESGMLDCLQLLHFHIGSQIPSTALLADGVGEAAQIYCELVRLGAGMKYIDCGGGLGIDYDGTKSCDSDCSVGYGLQEYASTVVQAVRFVCDRKNVKHPVICSESGRAIVSHHSVLIFEAVSSTTTRSQELSSVDLQSFVEKLNDDARADYRNLSAAAIRGEYDTCVLYADQLKQRCVEQFKDGNLDIEQLAAVDGICDFVSKAIGASDPVRTYHVNLSIFTSIPDFWAIDQLFPIVPIHKLDERPGVRGILSDLTCDSDGKIDKFIGGESSLPLHELGSNGGGDGGKYYLGMFLGGAYEEALGGLHNLFGGPSVLRVSQSDSPHSFAVTCAVPGPSCADVLRAMQHEPELMFETLKHRAEEFVHNDDEQEEDKGLAFASLASSLAQSFNNMPYLVTNSSCCLTATNNGGYYYCNDENIVGVGAESAAAEEELWPYCVA
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (PubMed:32242247).  Required for the biosynthesis of putrescine (By similarity).  Catalyzes the first step of polyamine (PA) biosynthesis to produce putrescine from arginine (By similarity).
What are the official names of this protein?
Arginine decarboxylase 1B, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NEP1_THEON
Sequence: MLHLVIADSELELAPKSIVDHPAIVNYAKRRNKKPEEVLLDSTYHHSALKKLEDGERRGRPDIVHVCLLNALESIANKEGKLRVYVHTRNDEVIYIKPETRIPRNYNRFVGLMESLFKNGVVPEGLELLRMEEKSLAELIDEIKPDGVFVMHENGESMKPQEFGKVLAGLQSPLVVVGGFPHGDFRSEIPGKKISLYKAPLMAWTVVNEIIINFEHWVL
What is the function of this protein?
Methyltransferase involved in ribosomal biogenesis.  Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase Nep1, 16S rRNA (pseudouridine-N1-)-methyltransferase Nep1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Protein: RS15_TREPA
Sequence: MALTKERTASVVQQYGSGEKDTGSSSVQIALLTERIRQLTDHCKVHPKDKSSNRGLLVLVGRRRRLLRYSRRVSMGAYRSLVKSLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FTHS_STRT2
Sequence: MKTDIEIAQSVELKPITEVVEKVGIGFDDLELYGKYKAKLSFDKINEVKDDKPGKLILVTAINPTPAGEGKSTISIGLADALNKIGKKTMIALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNALGIDQRRIIWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDINDLKERLANIVVAYRYDRTPVYVRDLEIEGALTLILKDAIKPNLVQTIYGTPALVHGGPFANIAHGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLDIKTPNLPTTPDAVVIVATLRALKMHGGVAKTDLSEENVQAVRDGFSNLKRHVENIRKFGIPVVVAINEFVADTEAEIAALKELCSEIKVPVELASVWANGADGGIDLANTVVDVVENGNADYKRLYSDDDSLEEKITKIVTEIYGGKSVVFEKKAKNQLKQFAEFGWDKLPVCMAKTQYSFSDNQFLLGAPEGFDITIREFVPKTGAGFIVALTGDVMTMPGLPKAPAALKMDVTEDGTAVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: MTX1_HUMAN
Sequence: MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDSPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTATIGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVPPQRQTPAGPETEEEPYRRRNQILSVLAGLAAMVGYALLSGIVSIQRATPARAPGTRTLGMAEEDEEE
What is the function of this protein?
Involved in transport of proteins into the mitochondrion.  Essential for embryonic development (By similarity).
What are the official names of this protein?
Metaxin-1, Mitochondrial outer membrane import complex protein 1.
What is the protein family that this protein belongs to?
Belongs to the metaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Mitochondrion outer membrane.
Protein: AHPD_MYCA9
Sequence: MSIENLKEALPEYAKDLKLNLGTVARGTVLSQSQLWGTLVATAAATRNEQVFKEIREEAAGILTPEALDAALGAASIMAMTNVFYRGRGFLDGAYDDLRPGLRMNIIGNPGVDKSEFELWSFAVSTINGCHYCVGSHEKVLREAGLTREQVLEALKIAAIVAGVAQALATVPALV
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: ATPF_MESHJ
Sequence: MVNLNQSLGDLFKGIIPNVYVLGATIVSFLILFLFITYFVYRPLKKYIKKRKDFLQNHIDLTIKSNVEAEKLEKKSQQKLLETKEFCIELKEKSQIEANEFLEDAKKTAIDNARQLINEGQKVLLEYENEIKSKYYMNVINVAVEICQKYLEKQDKNNKILQQSLIADLEKELKKRENSSKKKDNFGK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.