PharMolix/UniProtQA huggingface dataset:
Protein: LGT_VIBA3
Sequence: MSQGFIEFPNIDPVLIELGPISVRWYGLMYLVGFMFALWLANRRADQPDSGWTREQVSDLLFAGFLGVVLGGRIGYVLFYNFGLFIDDPLYLFKVWTGGMSFHGGLLGVITAMLWYAKKNGRTFFGVADMIAPLVPFGLGMGRMGNFMNSELWGRVTDVPWAIVFPNGGPLPRHPSQLYEMALEGIVLFFILNWFIKKPRPLGSVSGLFLAGYGTFRFLVEYVREPDAQLGLFGGFISMGQILSLPMVIIGVLMMVWAYKRGHYKDELPQQTK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PA2AC_CROVV
Sequence: NLVQFELLIMKVAKRSGLLSYSA
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that significantly inhibits ADP-induced platelet aggregation in platelet-rich plasma of human, rabbit and guinea pig.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 Cvv-E6c, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NU4LC_LOTJA
Sequence: MMLEHVLVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNMNLVTFSDFFDNRQLKGNIFSIFVIAIAAAEAAIGPAIVSSISRNRKSIRINQSNLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NCAP_I51A0
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYKRVDRKWMRELVLYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRKTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGPAVASGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACNSAAFEDLRVSSFIRGTKVIPRGKLSTRGVQIASNENMDTMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISIQPTFSVQRNLPFDKTTIMAAFTGNAEGRTSDMRAEIIRVMESAKPEEVSFQGRGVFELSDEKAANPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: NDHH_PROM1
Sequence: MAQLETRTEPMVVNFGPHHPSMHGVLRLVVTLDGEDVVDCEPVIGYLHRGMEKIAENRTNVMFVPYVSRMDYAAGMFYEAIVVNAPERLANIKVPKRASYIRAIMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGQRLINNNYFRIGGVACDLPWGWLEKCKDFCDWFGPKIDEYEKLITNNPIFRRRIEGLGVIGKEQAINWSLSGPMLRAAGVPWDLRKVDHYECYDDFEWDIAWEKEGDCYARYRVRIEEMRQSLKILRQACEMIPGGPTENLEAQRTVEGKKGDLSGFDYQYVAKKVAPTFKIPNGELYTRLESGKGEIGVFIQGNNDVTPWRFKIRAADSNNLQILPHILKGAKVADIMAILGSIDVIMGSVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase subunit H, NDH-1 subunit H, NDH-H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CH10_DESVH
Sequence: MNLKPLNDRVLVKRLESEEKTAGGLYIPDTAKEKPSRGEVVAAGPGKTADDGKLVAMTVKAGDMVLFNKYAGTEIKIDGVEHLVMREDDILAIIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_ECO5E
Sequence: MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNTQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_NITSB
Sequence: MELFGTDGVRGKAGKLLSAQLSMRLAMAAGIYFRKNSRTNKIVVGKDTRRSGYMIENALVSGLTAVGYNVIQVGPMPTPAIAFLTEDLRCDAGIMISASHNPYYDNGIKFFNHQGDKLQPEDEKAIEAIFFDEQTIEENQKTDQDIGSSKRIDDVIGRYIVHLKNSFPKDLTLNGLRVVIDTANGAAYKVAPTVFSELGAEVFVINDEPNGFNINEKCGAMYPGELAKKVREYRADIGFALDGDADRLVVVDEKGKIVPGDLVIGALATYLKQEGMLQADAIVATVMSNKALEDYLATLGIELVRSNVGDKYVLDEMKKRGINFGGESSGHIIFGDYSKTGDGIVTALQITAYMLRSQKGASEILYPFSLYPSKMENVTVKEKKPLETIEEFPELQKRIEKSGIRSLIRYSGTENKLRILLEGKDQKKLEKLMEELIQFFKERLS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y2690_HELPS
Sequence: MRFLNNKHRAKGLKAEEEACEFLKTLGFEMVERNFFSKFGEIDIIALKKGVLHFIEVKSGENFDPIYAITPSKLKKMIKTIRCYFSQKDPNSDFCIDALIVKNGKFELLENITF
What are the official names of this protein?
UPF0102 protein HPSH_02690.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: AB40G_ORYSJ
Sequence: MSHRHHAALVASASGRSPSWGSAISQSFRQVEAEDPFRRAQSMRGHDEEEEDLRWAALEKLPTYDRMRRGVVRSALLRDGDDDHKDDDDAGTGKAVELVDIGRLATGDAARALVERLLQDDSERFLRRLRDRIDMVGIELPKIEIRYEELSVQADAFVASRALPTLSNSAINFLQGLIGQFGSSNKKTINILKQVNGILKSSRMTLLLGPPSSGKSTLMRALTGKLDKNLKVFGNITYCGHKFSEFYPERTSAYVSQYDLHNAEMTVRETLDFSRWCLGIGSRYDMLTEISRRERNAGIKPDPEIDAFMKATAMQGQETNIITDLILKVLGLDICADTIVGDEMIRGISGGQMKRVTTGEMLTGPARALLMDEISTGLDSSSTFHIVKFIRHLVHIMNETVMISLLQPPPETYNLFDDIVLLSEGYIVYHGPRENILEFFEASGFRCPQRKAVADFLQEVTSKKDQQQYWFLDKEPYCYVSVPEFAERFKSFYIGQQMMKEQHIPFEKSKIHPAALTTMKNALSNWESLKAVLCREKLLMKRNSFLYIFKVTQLIILAFLSMTVFLRTKMPHGQFSDGTKFLGALTFNLITVMFNGLSELNLTVKKLPVFYKHRDFLFFPPWTFGVANILIKVPVSLVEATVWVVITYYVMGFAPAAGRFFRQFLAFFVTHLMAMALFRFLGAILQTMVIAISFGMLVLLIVFVFGGFVIRKNDIRPWWIWCYWASPMMYSQNAISINEFLASRWAIPNNDTTIDAKTVGEAILKSKGLFTGEWGFWLSIGALVGFIILFNTLYILALTYLSPIRSANALVIDEHNETELYTETRNEEHRSRTSTTTSSIPTSANGEGNRPTQSQFVLPFQPLSLCFNHLNYYVDMPSEMKQQGLMESRLQLLSDISGAFRPGLLTALVGVSGAGKTTLMDVLAGRKTSGTIEGSITLSGYSKKQETFARISGYCEQADIHSPNVTVYESILYSAWLRLPSDVDSNTRKMFVEEVMALVELDVLCNAMVGLPGVSGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVNTGRTVVCTIHQPSIDIFESFDELLLLKRGGRVIYAGELGDHSHKLVEYFETILGVPSITEGYNPATWMLEVSSTLEEARMNVDFAEIYANSLLYRKNQELIEELSIPPPGYRDLLFATKYSQSFYIQCVANLWKQYKSYWKNPSYNSLRYLTTFLYGLFFGTVFWQKGTKLDSQQDLYNLLGATYAAIFFIGATNCMSVQPVVSIERAVYYRESAAGMYSPLSYAFAQASVEFIYNIIQGILYTVIIYAMIGYDWKASKFFYFLFFIVSSFNYFTFFGMMLVACTPSALLANILITFALPLWNLFAGFLIFRKAIPIWWRWYYWANPVSWTIYGVIASQFGGNGGSISVPGGSHVAMSQILEDNVGVRHDFLGYVILAHFGFMAAFVLIFGYSIKFLNFQKR
What are the official names of this protein?
ABC transporter G family member 40, OsABCG40, Pleiotropic drug resistance protein 4, OsPDR4.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MT2_NICPL
Sequence: MSCCGGSCGCGSGCKCGSGCGGCGMYPDLEKSTTFTIIQGVAPMNNFEELGEKAAEGGNGCKCGSNCTCDPCNC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein type 2.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: SYR_HAEIE
Sequence: MNIQSILSDKIKQAMVIAGADQSCDALVRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQKVLDNLQLSDIAEKLEIAGPGFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYSSPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEHASEMELQDLEAFYREAKKHYDEDEIFAEKARNYVVKLQGGDEYCRAMWKRLVDITMQQNQHNYDRLNVTLTEKDVMGESLYNPMLPSIVEDLKKQGLAVEDDGALVVYLDEFKNKEGDPMGVIVQKKDGGFLYTTTDIAAAKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPDSFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIERATVLINEKNTNLSNDEKQAVIEAIGIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTEINSTALLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPILNAEDEAVKLSRLKLALLTEKTLKQGLELLGIKTVEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_RHIME
Sequence: MNTEAAGRRVHVIQGEFKVVNDPDIVLSTILGSCVAACMRDPAAGVGGMNHFLLPGSATSPSSGADATRYGVHLMELLINGLLKQGARRDRLEAKIFGGARTIARFSNVGEQNAAFARQFLMDEGIRIVGESTGGDHGRKLEYWPSSGRARQYALTGVEAQRALQMDQRPAVPKPAESPIEFF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: ILVD_PYRFU
Sequence: MRSDVIKKGIERAPHRSLFKAMGFTDEELERPLIGVANSFNELIPGHIHLRKIAEAVKAGIRMAGGTPLEFNTIGICDGIAMNHLGMKYSLPSRELIADSVELVARVYHFDGIVVIASCDKIIPGMLMAIARLNIPAIFVSGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSYEELKLLENFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAPYAHRIRIAKETGMQIVKLVEKDVKARDILTREAFEDAIAVDMALGGSTNTVLHLMAIANEAKVDLSLEDFDRISEKTPTLAKLSPAGKHFVVDLYEAGGILGVMKRLSELGLIHEDRLTVSLKTVGELLKSAFVSRDDVIRPVTNPYHPRGGIMILRGTLAPNGAVIKVSAVEGVEVFEGPAKVFDSEEEATAAILSGKIERGDVVVIRYEGPKGGPGMREMLTPTSAIAGMGLDKDVALVTDGRFSGATRGLSVGHVSPEAAEGGPIALVKDGDIIRIDLKNKRIDLLVDEEELRKRREEWKPKVKELTGYLKRYSTLVTSANTGAILRH
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: EFG2_SYNAS
Sequence: MPPKSRLSRIRNIGIIAHIDAGKTTVSERILYYTGKSYKIGEVHDGEAVMDWMPQEQERGITISSAVTTCNWANHEIHIIDTPGHVDFTIEVERSLRVLDGAVVVFDAVAGVEPQSETVWHQADKYGVPKIAFINKMDRVGADYFRVVKMMKERFASVPLPIQIPLGQQDQFLGVVDLIREKVVTWDDGSKGVNYQYSEIPGDREADAKANREIMLEILAEVDDGIAEKYLEGEEISESDLLRAIREATLANRLVPVMCGSALKNKGIQPVLDAVVNFLPSPEDVPPVRGIHPATKEELSRASSVKEPLSALAFKVMQDEGRKLTYIRIYSGQMKAGEELYNAGKKKKEKASRLLKMHANKRERLEQAGAGDIVAVMGLKETVTGDTICDEKNPILLESMEFYEPVISQAIEAKTPADQEKLSLALLKLMEEDPTLRVKYDEETAQTVISGMGELHLEVVIDRLGREFNAHVNVGKPRVVHRETIRNKVDVEGHFERELGDKKHFGHVRLVLEPKERGSGVEIEWKADTAILPAEYVKAVEEGIQESLVSGAVAGYPVVDIRIKILEVGLKEGESSPIGYKIAASSAFRDGCIKGESVLLQPIMAVNVITPAEFMGDVIGDINARKGEIQTITPKGAMCEIRALVPLKALFGYSTDLRSATQGRAVFTMQFYAYDQG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_AJECG
Sequence: MAVGKNKRLSKGKKGLKKRTQDPFSRKDEYSVKAPSTFAVRDVGKTLVNRTTGLKNANDSLKGRIFEVSLADLQNDEDHAFRKVKLRVDEVQGKNCLTNFHGLDFTSDKLRSLVRKWQTLIEANVTVKTTDDYLLRLFAIAFTKRRPNQIKKTTYARSSQIRAIRKKITEIIQREASTRTLAQLTKLIPEVIGREIEKSTHGIYPLQNVHIRKVKLLKSPKFDLGALLALHGESSTDDKGQKVEREFKEQVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_PROMM
Sequence: MHFQDIITTLNSFWADQGCVLLQPYDTEKGAGTMSPHTVLRAIGPEPWAVAYPEPCRRPTDGRYGDNPNRAQHYFQYQVLIKPSPVGIQETYLASLEALGVCTAEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGLDCSPVPIEITYGIERLAMYLQNVENIWDLSWNNKRSYGDIWLSLEKGQCDFNFESSDPSRLKQLFDLYEAEASDLIAKQLPAPALDFVLKCSHTFNLLEARGVISVTERTATIGRIRSLARGVAEAWLTEREAMGFPLLNNKALPLDQPLQS
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_DECAR
Sequence: MAKEKFARTKPHVNVGTIGHVDHGKTTLTAAITTVLSAKFGGAAKKYDEIDAAPEEKARGITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYVLVFMNKCDMVDDAELLELVEMELRELLSKYDFPGDDTPIIHGSALKALEGDQSEIGEPSIFRLADALDSYIPDPERAIDQPFLMPVEDVFSISGRGTVVTGRVERGIVKVGEEIEIVGIRPTVKTICTGVEMFRKLLDQGQAGDNIGALLRGTKREDVERGQVLCKPGSVKPHTHFTSEVYILSKDEGGRHTPFFNGYRPQFYFRTTDVTGSIELPEGTEMVMPGDNIAMTIKLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BREF5_EUPBR
Sequence: MANDVSGLGPTAFVRLLAFHLIGLFVSITVYRLFFHNLSGFRGPFIARLSSFYLAWLSAKRLHLHDEIDDLHSLYGDYVRTGPRELSIIDPQCVQVIYGSQTKCIKGPIYTLLDPRTNLSSTRDKTEHAKRRRAWDRGFSTTALHTYEPMVQELTEELMTIIDELSENPINITEWVDKYAFEVMGQLTFGKPFNMLKERKEAYFLELIRQDMNAIGYLLNLPWLSYLFLRTPGLNQNHLNFWRWIENEFAQRIARGQRRPDVFNWLHQAYLQGPQTKSDTLKLHGDGYLVIVAGSDTTASTITHLLFYLACNKALTQKLQAQLDALEGLTDESLRDVELLDACINETLRLRPAVPAGVQRETPKEGIYIGNRYIPGDTIVKVPMYTLFRDPRSFEQPNEFIPERFTTRPELVKDKSVFIPFLTGSYACVGRRLALMEVRRAVAAILCRYDIALAPGQNEEGFLDGKIDAFTLVAAPLSLKFTRRHQQKQ
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of brefeldin A (BFA), a protein transport inhibitor that shows antiviral, antifungal, and antitumor properties (PubMed:24845309).  The proposed biosynthesis of BFA involves formation of an acyclic polyketide chain that is differentially tailored throughout the backbone (PubMed:24845309).  The highly reducing polyketide synthase Bref-PKS is proposed to synthesize the precisely reduced octaketide precursor, which could then be directly offloaded by the thiohydrolase enzyme Bref-TH followed by a cytochrome P450 monooxygenase-mediated formation of the cyclopentane ring and macrocyclization to afford 7-deoxy BFA.  Alternatively, the first ring annulation can also occur on the ACP-tethered intermediate before the thiohydrolase release and lactonization (PubMed:24845309).  The C7-hydroxylation by another cytochrome P450 monooxygenase is believed to be the final step in the process to obtain the final structure of BFA (PubMed:24845309).  In addition to the HRPKS Bref-PKS and the thiohydrolase Bref-TH, the brefeldin A biosynthesis cluster contains 4 cytochrome p450 monooxygenases (called orf3 to orf6), as well a the probable cluster-specific transcription regulator orf8 (PubMed:24845309).
What are the official names of this protein?
Cytochrome P450 monooxygenase orf5, Brefeldin A biosynthesis cluster protein orf5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y4000_SHEFN
Sequence: MLGWTLMFLVIAVIAGLFGFTGIAGAAAGIAKIIFFIFIVLLVISLVANAIRGKAPRA
What are the official names of this protein?
UPF0391 membrane protein Sfri_4000.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HDEB_ECOL6
Sequence: MNISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFIDLNPKAMTPVAWWMLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQASNDLPN
What is the function of this protein?
Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach.  Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.
What are the official names of this protein?
Acid stress chaperone HdeB.
What is the protein family that this protein belongs to?
Belongs to the HdeB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: M6277_ASCSA
Sequence: MHYSPLTVLALLGGTLLLYCSGLVIYRLVFDPLSKFPGPKLSAATFWYEFYYDVIKKGQFTFKIGEWHKQYGPIIRINPYEIHIDDPEGDFYHTVFSGTGVRDKHFWYASQFGTPESGLGTINHHLHRHRRRALNPSFSKASIVRLTPVIWSKIEKLCSRFDELRGTDQPVNVRLAYTCLTTDVITSYAFNRCWNHLDKPDFSPVWCKTLVNGSKMTRWTKQFPWMLETMKKMPQALVGFFDPGMLLVFDVMNKIHHQILDILNGKQEVEDSATDGLSKSPIPNRTIFHELLKSDLPDYDKTIHHLGQEGQNIIGAGADTTSNALTVITYHLLSNPRVLGKLKEELERAMPDRYGAWDLKVAEGLPYLGGVIQEGLRLAYGASSRLTRVAPEEDLNFDGWFIQKGTPISMTALYMHHNEKIFPNSHTFLPERWTDAPDGGRSLDRYLVSFSKGSRQCIGINLAKVELFLTLATVFRRFEMDLHDTVFERDVQLKHDFFLPQPSMQSNGVRVIFK
What is the function of this protein?
Cytochrome P450 monooxygenase that hydroxylates polyporic acid produced by the nonribosomal peptide synthetase acyN to produce the less toxic metabolite ascocorynin (PubMed:35477441).  The hydrophobic substrate polyporic acid might approach the active site from the membrane and, after hydroxylation into ascocorynin, leaves into the cytoplasm (Probable).  MO6277 appears vital to avoid high-level accumulation of polyporic acid in the fungal membrane (PubMed:35477441).
What are the official names of this protein?
Cytochrome P450 monooxygenase MO6277, Ascocorynin biosynthesis protein MO6277.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RBFA_STRP6
Sequence: MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDLSLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYGNKIDQLLRELDNKS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_TRIEI
Sequence: MKVLLVRLIKGYKIFISPILPPSCRFQPTCSEYAMEAIERFGIFKGTAMAVMRILRCHPFHPGGYDPVPPKK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLYA3_PSEPF
Sequence: MFSKQDQIQGYDDALLAAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHVDKVEALAIERAKQLFGADYANVQPHSGSSANSAVYLALLQAGDTILGMSLAHGGHLTHGAKVSSSGKLYNAVQYGIDTKTGLIDYDEVERLAVECKPKMIVAGFSAYSKTLDFPRFRQIADKVGALLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLILAKANEEIEKKLNAAVFPGAQGGPLMHVIAGKAVCFKEALEPGFKAYQQQVIDNAQAMASVFIKRGYDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITVNKNAVPNDPQSPFVTSGLRIGTPAVTTRGFKVTQCVTLAGWICDILDNLGDADVEANVAQQVSALCADFPVYR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 3, SHMT 3, Serine methylase 3.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.