PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_ECO24
Sequence: MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_METAC
Sequence: MVKKVALAYSGGLDTSVCIPILKEKYGYDEVITISVDVGQPEEEIKKADAKAEKISNKHYTIDAKEEFVKDYIFPLIKANGDYEGYVMGTSVARPLIAKKVVEAAIKEGAVALAHGCTGKGNDQLRFEAVFRQTDMDVIAPMREMNLTREWEIDYAKEHGIPVEVTKAKPWSVDENIWSRSIEGGKLEDPSFVPPEEIFEWTKSAEDAPNEPRIVDIDFEAGVPVALDGEKLGGYALVRKLNEIAGENGVGRTDMIEDRVLGLKARENYEHPAATVLLAAHADLEKLVLTRGELKFKKIVDEQWSELAYYGLVDEPLYADLNAFIDKSQERVTGTVKVKLYKGALTILARSSPNALYSEDLVSFDSQTIDQKDAEGFAKYHGFQARMYRKVMEK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADL_ECO57
Sequence: MSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSGEGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVNISGTSPSGRSLKADNIAPTAWVPNMHFVAPINDQFGWGASITSNYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYRLNNAWSFGLGFNAVYARAKIERFAGDLGQLVAGQIMQSPAGKTPQGQALAATANGIDSNTKIAHLNGNQWGFGWNAGILYELDKNNRYALTYRSEVKIDFKGNYSSDLNRVFNNYGLPIPTATGGATQSGYLTLNLPEMWEVSGYNRVDPQWAIHYSLAYTSWSQFQQLKATSTSGDTLFQKHEGFKDAYRIALGTTYYYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRFWLSAGTTYAFNKDASVDVGVSYMHGQSVKINEGPYQFESEGKAWLFGTNFNYAF
What is the function of this protein?
Involved in translocation of long-chain fatty acids across the outer membrane.  FadL may form a specific channel (By similarity).
What are the official names of this protein?
Long-chain fatty acid transport protein, Outer membrane FadL protein, Outer membrane flp protein.
What is the protein family that this protein belongs to?
Belongs to the OmpP1/FadL family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SODE_MOUSE
Sequence: MLAFLFYGLLLAACGSVTMSNPGESSFDLADRLDPVEKIDRLDLVEKIGDTHAKVLEIWMELGRRREVDAAEMHAICRVQPSATLPPDQPQITGLVLFRQLGPGSRLEAYFSLEGFPAEQNASNRAIHVHEFGDLSQGCDSTGPHYNPMEVPHPQHPGDFGNFVVRNGQLWRHRVGLTASLAGPHAILGRSVVVHAGEDDLGKGGNQASLQNGNAGRRLACCVVGTSSSAAWESQTKERKKRRRESECKTT
What is the function of this protein?
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
What are the official names of this protein?
Extracellular superoxide dismutase [Cu-Zn], EC-SOD.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Golgi apparatus, trans-Golgi network.
Protein: SYH_LACDA
Sequence: MRVQRPKGTVDILPETSGQWEKVEQTARDLFKRANYHEIRTPSFENYELFSRSSGETSDVVEKEMYDFEDKGGRHIALRPEGTAGVVRAYVENKIYGPDYVKPFNVYYIAAMYRYERPQAGRQREFHQIGVESFGSNGYLADVETILLGHDLLAELGVKNYELHINTLGDSEVRQAYHDALVDYFTPVKDQLSEDSQRRLGKNPLRILDSKAEEDQQFLSEAPKIRDYLDEESKENFNKILASLDKLGVKYVIDDDLVRGLDYYTGVIFEFMVDDPTLWASPSTVLGGGRYNHLVEEFSGPETPAVGFGIGEERLMLVLSKQNPEMFEDQGIDFFITNIGEGTDIKAVEVARQLRSLGFSAQYDVDQKKLKAQFRKADRVGARYVVTLGAKELAEGKLTVKRLSDGQQFSLEFTDLEDKTNLLSKIEK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_NITWN
Sequence: MTAHDRGFDGVERRGLMFVLSSPSGAGKTTLSRLLIERVEGLSLSVSATTRPMRPGEVDGRDYAFVDEKTFAAMVERNDLLEWAHVFDNHYGTPRAPVDAALSSGRDVLFDIDWQGTQQLREKARDDVVSVFILPPSAADLERRLHTRAQDSDDVIRERMARAAHEVSHWAEYDYIVINRDIDEAFAEVQSILKAERLKRERRTGLTAFVRELQRQLET
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAT_PLAYO
Sequence: MEFVKDLKTPEDYINNELKYGAHNYDPIPVVLKRAKGVFVYDVNDKRYYDFLSAYSSVNQGHCHPNILNAMINQAKNLTICSRAFFSVPLGICERYLTNLLGYDKVLMMNTGAEANETAYKLCRKWGYEVKKIPENMAKIVVCKNNFSGRTLGCISASTTKKCTSNFGPFAPQFSKVPYDDLEALEEELKDPNVCAFIVEPIQGEAGVIVPSDNYLQGVYDICKKYNVLFVADEVQTGLGRTGKLLCVHHYNVKPDVILLGKALSGGHYPISAVLANDDIMLVIKPGEHGSTYGGNPLAASICVEALNVLINEKLCENAEKLGGPFLENLKRELKDSKIVRDVRGKGLLCAIEFKNELVNVLDICLKLKENGLITRDVHDKTIRLTPPLCITKEQLDECTEIIVKTVKFFDERF
What is the function of this protein?
Catalyzes the transamination of alpha-ketoglutarate with ornithine or N-acetylornithine and of glutamate-5-semialdehyde with glutamate and alanine.
What are the official names of this protein?
Ornithine aminotransferase, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGA_ENT38
Sequence: MVKERRTELVQGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSSIVNDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPIYHKHTRVTDAKTLELVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFIISQPLGVDDGVDYCHSGRIRRIDEEAIHRQLDSGAIVLMGPVAVSVTGESFNLTSEEVATQLAIKLKAEKMIGFCSSQGVFDEQGNIVSELFPNEAQARVETLEAEGDYHSGTVRFLRGAVKACRSGVRRSHLISYQEDGALLQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIQRDNLTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERVAAQARQIGLSKLFVLTTRSIHWFQERGFTPVDIDSLPESKKEMYNYQRRSKVLMADLG
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_BACC3
Sequence: MSRISKEEMSKLLSVYFIMGSNNCTKDPLQVLREALEGGITIFQFREKGEGALTGEERICFAKELQAICKEYGVPFIVNDDVELALELDADGVHVGQDDEGITSVREKMGDKIVGVSTHTIEEARWAIENGADYLGVGPIFPTSTKKDTKAVQGTKGLAHFREQGITIPIVGIGGISIENTASVIEAGADGVSVISAISLAESSYESTKKLVEEVSRSL
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RR14_NICTO
Sequence: MARKSLIQREKKRQKLEQKYHSIRRSSKKEISKVPSLSDKWEIYGKLQSPPRNSAPTRLHRRCFLTGRPRANYRDFGLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL14_CARHZ
Sequence: MIQVQTILNSADNTGAKKLMCIRVLGGSNRRYASLGDIIVCSVKEATPDAVVKKGEVVKAVVVRTKKEVRRPDGTYIKFDENAAVIIKDDKSPRGTRIFGPVARELREKDFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: UL09_HCMVM
Sequence: MSKRLQVFPWITILFYTSKSQYWNYMTIPCTPTVGYGSHNISLHPLNNSLFQDDVFEWYIDKPMVTNKLCLYQSNERIKSNLDSPNIMWQCTDNRTLILMNLTTTYSRNYYFQSFKYLGQGVPKPNNLCYNVSVHFTHQTHCHTTTSSLYPPTSVHDSLEISQSFTSTNFTHTAVHYAAGNVEAQHDTATSHTMWIIPLVIVITIIVLICFKFPQKAWNKFTQYRYSGMLAAA
What are the official names of this protein?
Membrane glycoprotein UL9.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 UL9 family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: TAP_BPP2
Sequence: MNKENVITLDNPVKRGEQVIEQVTLMKPSAGTLRGVSLAAVANSEVDALIKVLPRMTAPMLTEQEVAALELPDLVALAGKVVGFLSPNSVQ
What is the function of this protein?
Promotes tail assembly by creating a scaffold for the tail tube proteins.  Tail assembly proteins E and E' would wrap the linear tape measure protein to create a tail assembly scaffold.
What are the official names of this protein?
Tail assembly protein E, Gene product E, gpE, Tail assembly chaperone, TAC.
What is the protein family that this protein belongs to?
Belongs to the mulikevirus tail assembly protein family.
Protein: ILVD_PHOPR
Sequence: MPKYRSATTTHGRNMAGARALWRATGVKDEDFGKPIIAVVNSFTQFVPGHVHLKDMGQLVAGEIEKAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAALRLNIPVIFVSGGPMEAGKTKLSDQILKLDLVDAMIQGADPTVSDEQSEQIERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSMLATHADREQLFINAGKRIVDLTKRYYLNDDDTALPRNIANKKAFENAMALDIAMGGSTNTVLHLLAAAKEGDIDFDMDDIDRMSRLIPHLCKVAPSTPKYHMEDVHRAGGVYSILGELDRAGLLHNDTHNILGQTFAESLAEYDIAVTESQAVKDFFRAGPAGIRTTKAFSQSCRWDTLDDDRTNGCIRSKEHAFSQDGGLAVLSGNIAIKGCIVKTAGVDENSLVFSGPAVVFESQDTAVEGILGGKVKSGDVVVIRYEGPKGGPGMQEMLYPTTYLKSIGLGKECALITDGRFSGGTSGLSIGHVSPEAAAGGTIGLVNDGDIINIDIPNRSIELHVDDTELAQRRATADQQGWKPVNRQREVSYALRAYALLATSADQGAIRDKSKLEG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: FOLD_STRT1
Sequence: MAIIMDGKALAVNMQEQLQEKVARLKEKEWIVPGLVVIMVGENPASQVYVRNKERAAKKAGFHSKTVNLSESISEEELIEVIEKYNQNPLFHGILVQLPLPNHINEMRILLAIDPKKDVDGFHPMNTGNLWNGRPQMVPCTPAGIMEILREYNVELEGKTAVIIGRSNIVGKPMAQLLLEKNATVTLTHSRTPHLAKVCNKADVLIVAIGRAKFVTEEFVKEGAVVIDVGINRDEEGKLCGDVDFDQVKEKVSMITPVPGGVGPMTITMLMEQTYQAALRSLKG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HIS4_SYNWW
Sequence: MIIYPAIDLKDGQCVRLVQGRVENKTVYSDAPANVARSFQEQGASFLHIVDLDGAFQGSPQNLKAIEAIAAAIDISFQVGGGLRQLSDVEKLLALGASRVIIGTRAVSHPDFIANLLDKFGPERIVLGLDAKEGMVAVEGWVSTSSVSAIDFGLQMKALGIQTAIYTDVSRDGLLQGPNLAAIKEMASSTGLDIIASGGVSSLDNIRALKELENDGVSGAIIGKALYDGKIGLVDALREAESKF
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_STRS7
Sequence: MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLFVGALKAIAPLLVFALVVQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPLTLTLNTSVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKSVPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLVGTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDLGLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISACGASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAEKAFWKQKKA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PANB_METFK
Sequence: MNLLTLQQMKERGEKIAVLTSYDASFAALSDKAGVDVLLVGDSLGMTMQGHANTLAVSLRDMEYHTRCVANGTQHAFIVTDMPFGSFQKTPEQAFENAVLLMAAGAQMVKVEGGAIMLETVRFLVERGIPVCGHLGLTPQSVHQFGGYRVQARDEAAARQLLDDAKALAAAGAGMLVLEMVPAALAAAVSQAVHIPVIGIGAGKYCDGQVLVLQDMLGIYAGKSPRFVRNFMQGAGSIEQAICDYVAAVKAQTFPGIEHTFE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_CLOK1
Sequence: MSKEEIIQAIKGMSVLELNELVKACEEEFGVSAAAPVAVAGGAAAGGGDAAEEKTEFDVVLKASGSEKIKVIKAVREVTGLGLKEAKALVDGAPKPLKEAVSKEDAEAIKAKFEEIGAEIELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: YCGL_SALNS
Sequence: MRQVTIPLIQSKSMFCVIYRSSKRDQTYLYVEKKDDFSRVPEALMKGFGQPQLAMMLPLDGRKKLVNAELEKVKQALSEQGYYLQLPPPPEDLLKQHLSSVGQNTSSADR
What are the official names of this protein?
Protein YcgL.
Protein: RNC_COXBN
Sequence: MNHLNKLMERLGHQFNNLELLKIALTHRSSGADNNERLEFLGDSVLGFIIASELYQRRPQAREGDLSRMRASMVNGDELAQMSTKLGINEYLQLGVGEQKSGGKRRRSILADALEAIVGAIYIDAGLETCRRCVLNWYGERVDDLSKLSPKKDAKSLLQEWLQARRLPLPTYEVKITGEAHAQTFTVNCYVKGLPHKTEGVNTTRRRAEQIAAKRFLELLDDGKGDGITERDQ
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_LACP7
Sequence: MDIISLKAYAKINLALDVIGKRPNGYHDVRMIMQTIKLYDKITIKPTTNPDITIKTNLHFLPTNENNIVYTACKLFKDTFQISDGFYINLEKRIPVAAGMAGGSSDAAATLFGLNELFQTNQSLEDLMKLGVKLGADVPYCLLRGTALSEGIGEVLTPLPPAPNCYCLIVKPPVSVSTKFVYENLKLDENTKHPNIDGMVEAIEKQDLHQMSSLVSNVLESVTIKHHPEIERIKMDLLSHGALNALMSGSGPTVFALFDNQKAAERAFYEYKVGPYGKQTFLTRFFESKNV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: INSB2_ECOLI
Sequence: MPGNRPHYGRWPQHDFPPFKKLRPQSVTSRIQPGSDVIVCAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVEQHDKVIGHYLNIKHYQ
What is the function of this protein?
Absolutely required for transposition of IS1.
What are the official names of this protein?
Insertion element IS1 2 protein InsB, IS1b.
What is the protein family that this protein belongs to?
Belongs to the transposase 27 family.
Protein: Y1178_STAAN
Sequence: MATWLAIIFIVAALILGLIGGFLLARKYMMDYLKKNPPINEEMLRMMMMQMGQKPSQKKINQMMTMMNKNMDQNMKSAKK
What are the official names of this protein?
UPF0154 protein SA1178.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SEPF_LISMO
Sequence: MGLSNKFKSFFFLDEEEEYYEEEVAREPEPMQKKTKKEKPNKNRFYAVEEDDAKVVSMQGAQFSSRMVLAEPRVYAEAQELADYLKEYKSVVVNLQRISHDQATRIVDFLSGTVYALGGDIQRVGNNIFLCTPDNVEVDGSISEMLDEQNFM
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: ARF1_DROME
Sequence: MGNVFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRDAVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLKNANR
What is the function of this protein?
Small GTPase involved in protein trafficking between different compartments.  Modulates vesicle budding and uncoating within the Golgi complex.  In its GTP-bound form, triggers the recruitment of coatomer proteins to the Golgi membrane.  The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles (By similarity).  Has a role in eye development (PubMed:21976699).  Required for cleavage furrow ingression in embryonic cells (PubMed:27535433).
What are the official names of this protein?
ADP-ribosylation factor 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasm, cytosol. Note=Localization to the Golgi is dependent on Asap.
Protein: PIMT_AZOC5
Sequence: MTDSEAERAERAAFILSLRRRGIRDLAVLRALELVPRGLFVDPTLRRHAYEDVALPIACGQTMSQPSLVALMTEALALNAEHTVLEIGTGSGYQAAVLSHLAAQVVTMDRYRALVGEAQTRFQVLGLRNVAAFVGDGTQGLPGRAPYDRIMITAATGEVPRALVDQLKPGGVLIAPIGAPREVQKLRRFIKDGGNLEASDLMDVRFVPLVAGVAALL
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_PELPD
Sequence: MSMNRFRETLQRATEEMQFELSGEQLRDFQLFAMELKKWNLRVNLTAITDDGEIAVKHIADSLFLARQLDSTERVLDVGSGAGIPAIPLKIAIPGLETVSVDAVGKKIHFQRHVARLLRLQGFQALHARIESLHATHGRSFDVITSRAFSDLGLFVRLTAPLLAEGGRLIAMKGPAAGDEMEEAKTTLAALRHEVCSLHPYRLPLESGERCLVVMRPVSKI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAJ_SYNY3
Sequence: MDGLKSFLSTAPVMIMALLTFTAGILIEFNRFYPDLLFHP
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RS20_MYCSJ
Sequence: MANIKSQEKRIRTNERRRLRNQSVKSSLRTAVRGFREALDAGDKDKAAELLVATSRKLDKAASKGVIHKNQAANKKSALSVALNKL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: TRPE_BUCSC
Sequence: MCEHLKSMDVLKVETFYQPNPTAIFHHICRNRSNTLLLESAEINNKKNLESMMIVDSALRISALNMVVTLEALTKNGESLLPVFKSLLPKEVRILSNDNFLKIKFPSIVKDIDEDKKLHVLSIFDSIRFLINSVKNNKGSKSMFFGGLFAYDLVSSFENLPKLKTSQSCPDFCFYLSEILLVLNHKRRTCYIQASLFSSSNLERNKLQHRLLEVKNKLSQNFYPLESTSLKKMILKCNRTDREYEKIIKEMKKSIMIGEIFQVVPSRKFYLPCTNSLAAYDVLKKNNPSPYMFFMQDSNFTLFGASPESSLKYDTLSRKIEIYPIAGTRPRARKIDGSIDLDLDSRIELEMRTNHKELSEHLMLVDLARNDLAKICDPGTRYVADLTQVDKYSHVMHLVSRVVGKLRLDLDVFHAYQACMNMGTLSGAPKIRAMELISNAEKEKRGSYGGSIGYFTASGTLDMCIIIRSAYVENNIATIQVGAGIVLDSIPQLEVDESKNKAKAVLQAISESHSCHIELNIENERHTFAG
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: NKD2_HUMAN
Sequence: MGKLQSKHAAAARKRRESPEGDSFVASAYASGRKGAEEAERRARDKQELPNGDPKEGPFREDQCPLQVALPAEKAEGREHPGQLLSADDGERAANREGPRGPGGQRLNIDALQCDVSVEEDDRQEWTFTLYDFDNCGKVTREDMSSLMHTIYEVVDASVNHSSGSSKTLRVKLTVSPEPSSKRKEGPPAGQDREPTRCRMEGELAEEPRVADRRLSAHVRRPSTDPQPCSERGPYCVDENTERRNHYLDLAGIENYTSRFGPGSPPVQAKQEPQGRASHLQARSRSQEPDTHAVHHRRSQVLVEHVVPASEPAARALDTQPRPKGPEKQFLKSPKGSGKPPGVPASSKSGKAFSYYLPAVLPPQAPQDGHHLPQPPPPPYGHKRYRQKGREGHSPLKAPHAQPATVEHEVVRDLPPTPAGEGYAVPVIQRHEHHHHHEHHHHHHHHHFHPS
What is the function of this protein?
Cell autonomous antagonist of the canonical Wnt signaling pathway.  May activate a second Wnt signaling pathway that controls planar cell polarity (By similarity).  Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells.
What are the official names of this protein?
Protein naked cuticle homolog 2, Naked-2, hNkd2.
What is the protein family that this protein belongs to?
Belongs to the NKD family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Cytoplasmic vesicle.
Protein: LGT_PROMA
Sequence: MEGIIATFRSPGAELIELGTLTVRWYGILIAISVLIGLKLSTRLGSYRNINPGIINDLMPILILSSIFGARFYYVSFEWNNYNGVNFWSKVHLLGLQIPIPSFLEIWNGGIAIHGALIMGTISIILFCRIKKQRFWDVLDVLVPSVALGQAIGRWGNFFNNEAFGLPTNQPWKLFIPFSSRPESFSDQSYFHPTFLYESLWNICIFLILIFLFRLNIRGLMKLPSGALSCIYLITYSLGRIWIEGLRIDPLCLGGSPPFCEGGLRIAQLISFLLICLGSFGLWWIYQSKRKMPNFGITRNRKK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.