PharMolix/UniProtQA huggingface dataset:
Protein: DDL_RICRS
Sequence: MHKYQTHWVEHSIVKILSSTGKKHIALMAGGMSAEREVSLVSSEGVSKALIELGYRVTFIDMGADIAVRLQEIKPDIVFNCLHGTYGEDGGLPGLLNIMRIPYTHSGVLSSALAFDKIHSRIWFLTNNINMAESIVVNKSDNIKNDPMKRPYVIKPLTQGSSIGVEVIFAEDDFNFADYDFPYGDQVIIEQYIKGRELQVAVLNGKALGALEIKLLKNRFYDYETKYTAGFADHLCPAPLPANLYEKLLIESEKIYKTMNCKGPARAEFILEEQTNKLYALEINTHPGMMSLSIVPEIAAYAGINFTNLIEEIIKTASFES
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RABP1_HIPCM
Sequence: MPNFAGTWKMKSSENFDELLKALGVNAMLRKLAVTAASKPHVEIQQNGEQFYIRTYTTIRTTEINFHIGEEFNEETVDGRKCKSLATWETENKMYCKQTLLSGNGPKTFWTRELRGDELILTFGADDVVCTRIYMRA
What is the function of this protein?
Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.
What are the official names of this protein?
Cellular retinoic acid-binding protein 1, Cellular retinoic acid-binding protein I, CRABP-I.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S7A6O_DANRE
Sequence: MDPSTTILRVKRKRGTDPADALLLACKRIRPEATAAQPSDESEPEPQEPKIENSVFKLVATVVSQDAPVQPHVREALARPRLAHHALRPSQGSSQRIIGDLRSVKWSTRREERYRILSSHRAGLPSEPAPAGGGGEENHDSHAESRDGLPLGEVQVFDILHEEEDVKVPGKMVVSDPETILCNSVKMIREKLSVSGAGLGTEHREKEDDYVYDLYYQETATPGWIQDILSVRPYSQEGELVPDEVAWEEEVYEDEDDENAEANWRNDYPEESSEGDSEGEERYGGCWSEEHSYSRRSRECYRRDMIDELENDKDEDDEEREYNDSD
What is the function of this protein?
Directs RNA polymerase II nuclear import.
What are the official names of this protein?
Probable RNA polymerase II nuclear localization protein SLC7A6OS, Solute carrier family 7 member 6 opposite strand transcript homolog.
What is the protein family that this protein belongs to?
Belongs to the IWR1/SLC7A6OS family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HCD2_DROME
Sequence: MIKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVTSEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDGALRMMP
What is the function of this protein?
Versatile enzyme presenting two types of activity; L-3-hydroxyacyl-CoA dehydrogenase ((3S)-3-hydroxyacyl-CoA dehydrogenase) activity and hydroxysteroid dehydrogenase (HSD) activity with a wide substrate spectrum.  As a (3S)-3-hydroxyacyl-CoA dehydrogenase, it functions in the third step of the fatty acid beta-oxidation pathway, a major metabolic process in which fatty acids are oxidized to provide a significant source of energy, while also generating acyl-CoA metabolites used by many metabolic routes (PubMed:12917011) (Probable).  As a HSD, it functions in the degradation pathways of glucocorticoids and sex steroids and epimerization of bile acids; catalyzes the beta-oxidation at position 17 of androgens and estrogens, has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone, and carries out oxidative conversions of 7-beta-hydroxylated bile acids like ursodeoxycholate or isoursodeoxycholate (also known as 3-beta,7-beta-dihydroxy-5-beta-cholan-24-oate or 7-beta-hydroxyisolithocholate, respectively).  Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids (PubMed:12917011).  Required for cell survival during embryonic development.  May play a role in germline formation (PubMed:9585418, PubMed:12917011).
What are the official names of this protein?
3-hydroxyacyl-CoA dehydrogenase type-2, 17-beta-hydroxysteroid dehydrogenase 10, 17-beta-HSD 10, 3-hydroxyacyl-CoA dehydrogenase type II, Hydroxysteroid dehydrogenase, Mitochondrial ribonuclease P protein 2, Mitochondrial RNase P protein 2, Scully protein, Type II HADH.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Localizes to the lipid droplet fraction in early embryos (PubMed:16979555). Co- localization with mitochondrial markers for human, but not for the Drosophila form (PubMed:12917011).
Protein: ANMK_BACC2
Sequence: MYIAGVMSGTSLDGIDVALVHIEGSGVDSKIELIHFTTVPFCNDMKNEIQQALSIETSNVQLICSLNFKLGLCFANAVKEVCKEANFPLRQLDLIGSHGQTIYHQPKQEGNIISSTLQIGEPAVIAYETNTTVISNFRTMDMAAGGQGAPLVPYSEIILYRHQTKNRLLQNIGGIGNVTVVPSKRSNESVIAFDTGPGNMIIDEVCQRLFQLSYDQNGKIAKQGVVVDEILTYCMNHPFLNVKPPKSTGREQFGEAFVTELLNRFEKHSRENILATVTMFTASSIVHHYQEFIFPYYEIDEVILGGGGSYNRTLVEMIRFGLKEEKCKIFTQEDLGYSSAAKEAIAFAILANETYHRNPSNVPSATGAKQSVVLGNITFPPI
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ACDH_BACC1
Sequence: MKKVKAAIIGSGNIGTDLMYKLKNSKVIELNAMIGIDSESDGLKRAKEAGYEVFDNGIQAIIDNPSLADIVFDATSAKAHSYHAKILEELGKIVIDLTPAAYGPFVCPAIRNNDFLDKQNVNMITCGGQATIPIVHAINEVANVTYAEIVATISSLSAGPGTRANIDEFTITTKRGIEEIGGADKGKAIIILNPAEPPILMRDTIYCEVKDMDEVSIYEAIHKMVERVRTYVPGYSLKQEPMFDGNRVTVFLEVEGAGDYFPPYAGNLDIMTAAALKVGEEFATQIVSEKKRGVMNEAK
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: AROC_STRM5
Sequence: MSSNSFGKLFTVTTFGESHGPAIGCVIDGCPPGLALDAAEFAHDLQRRATGKSRHTSARREADEVEILSGVYEGLTTGTPIALLIRNTDQRSKDYANIGQQFRPGHADYSYWHKYGIRDPRGGGRSSARETTMRVAAGVVAKKWLAERFGVTVRGYLSQLGEITPAGFDWSAVKDNPFFWPHAAQVPELEAYMDALRKSGDSVGACVDVVADNVPPGWGEPIYGKLDGDLAAALMSINAVKGVEIGDGFASAVQKGTEHRDLLTPQGFASNHAGGILGGISTGQPVVASIVLKPTSSLRLPGPSLDTSGNVVEVVTTGRHDPCVGIRATPIAEAMVAMVLMDQALRHRAQCGDVGTITPRIPGQFDG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: TRMB_STRT1
Sequence: MRVRKRKGAEEHLANHPQYVILEPEAAKGKWHQIFGNDNPIHIEVGSGKGAFITGMAQQNPDINYIGIDIQLSVLSYALDKVLASGVENVKLLRVDGSALTNYFEDGEVDMMYLNFSDPWPKSRHEKRRLTYKTFLDTYKQILPKNGEIHLKTDNRGFFEYSLTSFSQYGMILNKVWLDLHASDYEGNVMTEYERKFSEKGQAIYRVEAQFKD
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: SHEP_DROMO
Sequence: MGGPHHQHQQHQQQQQVVGGGNGHGGGAPVHMRAPPNSQQLPPQMPRSQNYANGSSSAASVAAAPPTPRSAFPGAPLTASAVALKGAIPQRPPAMTSPAAAAAGAALAAGAPYRGATSWTPQGYAPAAAAAAAAVAQQAYRYTAPLPQPAYAAYTPHTATTPATTTYGQRVPTAASPSNTNSSSSSNTGSQSGTLSTSLSNTTNTNTTMGPNGTAQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLINMCAQYGTIISTKAILDKTTNKCKGYGFVDFEQPAYAEGAVKGLQAKGVQAQMAKVGIWVLHRPAIQQEQDPTNLYIANLPPHFKETDLEAMLAKFGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGNTITGAKDPLLVKFADGGPKKKNLFKTPDPNARAWRDVSAEGIPVAYDPTMQQNGVSVNVGTPIGVPYSRFGAPQVGGYPVAGSQWIPGYMMTQPITQVDDQYSSSALQYMQMAAAPQLGVTSYKPQEVNQVPARGISMMVSGDTAVPYGTMMPQLATLQIGNSYISPTYPYYAPPPTILPTMPMTDSEQASTAASPDEAYTQYPHQAAPK
What is the function of this protein?
Has a role in the perception of gravity.
What are the official names of this protein?
Protein alan shepard.
Protein: RGN_CHICK
Sequence: MSSVKIECVGSDRYRLGESPVWDEKENSLLCVDITGRKVCRWDAASGQVQALSVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTIAQVDRDKANNRFNDGKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLCPDHSVVKHFDQVDISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSVYKLEKEESIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRIQTVKLPVDKTTSCCFGGKDYSEMYVTSASDGMDREWLSRQPQAGGVFKITGLGVKGIPPYPFAG
What is the function of this protein?
Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone.  Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis.  Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro).  Calcium-binding protein.  Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity).
What are the official names of this protein?
Regucalcin, RC, Gluconolactonase, GNL.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RED3_COCH4
Sequence: MGLVKGNCGCYWGIKGHWSRNCSPVCEIANKNYYSRRGIAPRRTFWSVSNKSLVHLDANSLMIDYENVFYYTTDITSNKAIIESSERIRQDHGNPSVLINNAGVANGKTILEESEDERRRVFNVDILAHFSLVREFLPDMIKHNHGHIVTVASTASFLARPQLVSYSCCKTALIAFHEGLSQELRMRHNARKVRTT
What is the function of this protein?
Dehydrogenase; part of the Tox1B locus, one of the 2 loci that mediate the biosynthesis of T-toxin, a family of linear polyketides 37 to 45 carbons in length, of which the major component is 41 carbons, and which leads to high virulence to maize (PubMed:8953776, PubMed:20192833).  One of the PKSs (PKS1 or PKS2) could synthesize a precursor, used subsequently by the other PKS as starter unit, to add additional carbons (PubMed:16529376).  Variability in the length of the final carbon backbone C35-47 could be achieved by varying the number of condensation cycles, or use of different starter or extender units or might be due to decarboxylation of the penultimate product, catalyzed by DEC1 (PubMed:12236595).  Additional proteins are required for the biosynthesis of T-toxin, including oxidoreductases RED1, RED2, RED3, LAM1 and OXI1, as well as esterase TOX9 (PubMed:20192833).
What are the official names of this protein?
Dehydrogenase RED3, T-toxin biosynthesis protein RED3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: NDK_AQUAE
Sequence: MAVERTLIIVKPDAMEKGALGKILDRFIQEGFQIKALKMFRFTPEKAGEFYYVHRERPFFQELVEFMSSGPVVAAVLEGEDAIKRVREIIGPTDSEEARKVAPNSIRAQFGTDKGKNAIHASDSPESAQYEICFIFSGLEIV
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTA_SALAL
Sequence: MDPCECSKTGSCNCGGSCKCSNCACTSCKKASCCDCCPSGCSKCASGCVCKGKTCDTSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein A, MT-A.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: MIAA_NOSP7
Sequence: MTKLIVICGATATGKSSLALALAMRLGSVIISADSRQVYRKFDIGTAKPTVAEQKLVPHYLIDICDPTDTMTVADYQEQTQALIASVDVTPLLLVGGTGLYIRSIVQGMKIPRVAPQIELRSQLESLGQLQLYAMLQQVDPVAAQKIHANDSVRTLRALEVYYVTGCPISEQQGENPPNYPILQIGLDCDVEKLGNRIKQRTEQMIADGLVAEVEYLCQKYGADLSLLNTLGYQEIKQYLAGDISLDEAKELTILHTRQFAKRQRTWFRAYPQIEWFDANNPDLLDKIWLRINEFTNCTHSS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: YIDC_RICBR
Sequence: MNNNIVNLVAAIVLSLGIIFGWQYFIVKPQQQKQQQQIALQKAKDLKKKESAQLEATPVIVQEASQAPRIKIDSNALSGSISLKGLRFDDLILKKYKQDLSENSPEVVLFSPSDTKDAYFAEIGWVSNLSSVKLPNNETIWNSDSEILTPEKPVNLFWVNEDGVKFLVAITVDENYLFTIEQTIVNNSNQELPVQSYGLINRKYTAVEKAVNILHQGPIGCIDENLKEYSYDDIKDKKSEKFSASKVDWIGITDKYWLTSLIPDKSSNYSSNFNYAVKQEVERYQVDFISPVQIVKPGENFSIKGRLFAGAKKVDLLDKYEKQYDIKLFDRAIDFGWFYIITKPVFYAMNFFYKYVGNFGISILIVTVIIKLLMFTLANKSYRSMKRMKNLQPEINRIKNLYGDDKARLNQEIMALYKKEKVNPVAGCLPILVQIPVFFSIYKVLYVTIEMRQAPFYGWIKDLSAPDPTSIFNLFGLLHFSLPSFLMIGAWPILMAITMFLQQRMSPEPADPVQAQVMKFMPLVFLVMFSSFPAGLLIYWSWNNILSIIQQYYINKLDK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CDSA_CHLMU
Sequence: MFDSDKNSILQSDFCQRLVVHSLLLVFLVILLCTSLYPSSAFIVGLLSSTCAAIGTYEMSSMVRMKFPFSFTRYSSIGSAIFVALTCLTARCKMLLPEHVDLIPWFFLFFWTVHLVFKSRHYKLGPIGSTGLALFCMLYVSVPIRLFLHILYGFVHTDTPFIGIWWAIFLIATTKSSDIFGYFFGKAFGKKRIAPVISPNKTVVGFVAGCIASILVSLIFYSHLPKSFANQIAMPWILVALGIILGISGFFGDIIESTFKRDAQIKNSSDLESIGGMLDVLDSLLLSTPIVYAILLITQNGTFLG
What are the official names of this protein?
Phosphatidate cytidylyltransferase, CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CTP:phosphatidate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROB_ECOUT
Sequence: MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S19A3_HUMAN
Sequence: MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAEITNEIFPVWTYSYLVLLLPVFVLTDYVRYKPVIILQGISFIITWLLLLFGQGVKTMQVVEFFYGMVTAAEVAYYAYIYSVVSPEHYQRVSGYCRSVTLAAYTAGSVLAQLLVSLANMSYFYLNVISLASVSVAFLFSLFLPMPKKSMFFHAKPSREIKKSSSVNPVLEETHEGEAPGCEEQKPTSEILSTSGKLNKGQLNSLKPSNVTVDVFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQVLNYVQILWDYKAPSQDSSIYNGAVEAIATFGGAVAAFAVGYVKVNWDLLGELALVVFSVVNAGSLFLMHYTANIWACYAGYLIFKSSYMLLITIAVFQIAVNLNVERYALVFGINTFIALVIQTIMTVIVVDQRGLNLPVSIQFLVYGSYFAVIAGIFLMRSMYITYSTKSQKDVQSPAPSENPDVSHPEEESNIIMSTKL
What is the function of this protein?
Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism.  Has no folate transport activity.
What are the official names of this protein?
Thiamine transporter 2, ThTr-2, ThTr2, Solute carrier family 19 member 3.
What is the protein family that this protein belongs to?
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MUTS2_STRT1
Sequence: MNTKILDQLEFNKVKDQFTEYLQTEQAQAELCDLVPMTNPERIQNQFTEIQEMSEIFVEHHGFAIGSLRDISEPLRRLELDADLNIQELIAIKKVLQASADLSRFYADLENVELIALKRLFEKIEAFPSLQGSLQSINDGGFIEHFASPELQNIRRQLKACDDAIRQTLQDILKKSGHMLAENLIASRNGRSVLPVKNTYRNRIAGVVHDISSSGNTVYIEPRAVIQLNEKITQLRADERHEMARILHELSDQLRPHTAAIANNAWILGHMDFIRGKYLYLHDKKAIIPEISDNQTLQLLNVRHPLLINPVANDLRFDEDLTVIVITGPNTGGKTVMLKTLGLAQLMAQSGLPILADKGSRVAIFQEIFADIGDEQSIEQSLSTFSSHMTHIVEILNTADSNSLVLVDELGAGTDPQEGASLAMAILEHLRLSQIKTMATTHYPELKAYGIETQHVENASMEFDTATLRPTYRFMQGVPGRSNAFEIARRLGLNEIIVKEAENLTDTDSDVNRIIEQLEAQTVETQKRLEHIKDVEQENLKFNRAVKKLYNEFSHEYDKELEKAQKEIQEMVDTALAESDSILKNLHDKSQLKPHEVIDAKGKLKKLAAQVDLSKNKVLRKAKKEKAARAPRVGDDIIVTAYGQRGTLTSQAKNGNWEAQVGLIKMSLKADEFTLVRTQAEAQQPKKKQINVVKKAKKTSSDGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVEIIHGIGTGVIRDAVTKYLRRHRHVKNFEYAPQSAGGSGCTIATLG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: LUXS_ACTP7
Sequence: MPLLDSFKVDHTRMNAPAVRVAKTMTTPKGDTITVFDLRFCRPNIDILPVRGIHTMEHLFAGFMRDHLNSESVEIIDISPMGCRTGFYMSLIGAPSEADVVSAWTKSMEDALNKVPDVSKIPELNEYQCGSYKEHSLEEAHQIARDVLAKGIGVNRNEDLALDEKLLNP
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: DNAJ_BIFLO
Sequence: MADYYETLGVERGASDDEIKKAYRKLSRKYHPDIAGPEFEDKFKEVNNAYDVLSNPDKRRMYDSGVDPNNPNAGAGGFSGAGFGDMSDVFSTFFGSAFGGGSQGPVPRTQPGRDALASASIDLKTAVFGGTAHVKINTFSLCQECGGSGAQGGAQPVTCPDCHGQGFMQKVVRTMLGQMMTSAPCERCEGHGTIIQNPCPSCMGHGRVRTTRTVGVTVPAGINDNARLRLANQGEVGEGGGAAGDLYIDIRIKADKQFTRDGDDLHCWIQVPMSWAVLGHDLSIDTFDGEKTVSIPAGCQTEDTVTLKGLGVTNIRNKDERGNLIAHVNVLIPTKLNETERGLIEQFAASHDSGATHVSQASRPQAGQKKGFFSKLKDALS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_ALIF1
Sequence: MKHIRNFSIIAHIDHGKSTLSDRLIQVCGGLSDREMAAQVLDSMDLERERGITIKAQSVTLDYTAKDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMDLEVVPILNKIDLPAADPDRVAEEIEEIVGIDATDATRCSAKTGLGVDEVLETIVKSIPAPEGDPEAPTQALIIDSWFDNYLGVVSLVRIKNGSLKKNDKIKVMSTGQVWGIDRIGIFTPKQIDTDVLNTGEVGWVVCGIKDILGAPVGDTLTHAKGGCEERLPGFQKVKPQVYAGLFPVSSDDYENFRDALGKLSLNDASLFYEPESSAALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPTVVYEVAKTDGEILYVDSPAKLPAVNDIDEIREPIARCNILVPSDYLGNVITLCVEKRGVQVDMQYHGNQVAVTYDVPMAEVVLDFFDRLKSTSRGYASLDYNFQRYEASSMVRVDVLLNGDKVDALAIITHKDNSQSRGRLLVEKMKEFIPRQMFDIAIQAAIGNHIIARSTVKQLRKNVIAKCYGGDVSRKKKLLKKQKEGKKRMKQIGNVELPQEAFLAILHVGKD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL32_STAAC
Sequence: MAVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGEYKLSHRVCKNCGSYNGEEVAAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: UBIG_PSESM
Sequence: MSNVDRAEIAKFEALAHRWWDRESEFKPLHDINPLRVNWIDERANLAGKKVLDVGCGGGILSEAMALRGATVTGIDMGEAPLAVAQLHQLESGVSVEYRQITAEDLAEEMPEQFDVVTCLEMLEHVPDPSSVIRACHRMVKPGGQVFFSTINRNPKAYLFAVVGAEYILNLLPRGTHDFKKFIRPSELGAWSRDAGLQVKDIIGLTYNPLTKHYKLASDVDVNYMIQTLREA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: RUVA_PORG3
Sequence: MIEYLKGAIVGLTPTNLVIECAGVGYDVNVSLTTYSAYQGKKEGLIWITQLIREDAHLLYGFSTKEERTLFGQLTSVSGVGPTTARLILSSYAPQELAALITTGQADALKAVKGIGLKTAQRIIVDLKGKIQLETSSDEILSARTAVGDAALNTIASGEEAISALKMLGFADPAIRKAVKSILSEDSSLAVEDIIKRALRML
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.