PharMolix/UniProtQA huggingface dataset:
Protein: Y2352_CLOB8
Sequence: MNTNNILETIKMIEEEKLDVRTITMGISLLDCIDPDGDKARIKIYDKITKSAEHLVEVGRQIETEFGIPIVNKRVSITPMSIIAGATNETSYVEFARTLDRAAETLGIDFLGGFSALVQKGCTKGDKILISSIPEALAVTKKVCASVNVGCTKSGINMNAVRDMADVIKRTAELTKDQKGFGCAKLVVFANAVEDNPFMAGAFHGVGEAERIINVGVSGPGVVKRALEKVRGASFDVVAETIKQTAFKVTRMGELVANEASRRLDVPFGIVDLSLAPTPAVGDSVAEILEEIGLEQVGTHGTIAALAMLNDAVKKGGVMACSHVGGLSGAFIPVSEDAGMIDAVISGSLNLEKLEGMTCVCSVGLDMIAIPGDTPASTIAGMIADEAAIGVINNKTTAVRIIPAPGCEIGDMVEFGGLLGRAPVMKVNGKSSELFAQRGGRIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein Cbei_2352.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: RL11_LIMRD
Sequence: MAKKVANIVKLQIPAGAATPAPPVGPALGQAGINIMGFTKEFNARTADQKGMLIPVVITVYEDRSFDFITKTPPAAVLLKKAAGVEHGSGEPNTNKVASVTKDQVKEIAETKMQDLNAADVEAAMRMIEGTARSMGFTVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SMO_DROME
Sequence: MQYLNFPRMPNIMMFLEVAILCLWVVADASASSAKFGSTTPASAQQSDVELEPINGTLNYRLYAKKGRDDKPWFDGLDSRHIQCVRRARCYPTSNATNTCFGSKLPYELSSLDLTDFHTEKELNDKLNDYYALKHVPKCWAAIQPFLCAVFKPKCEKINGEDMVYLPSYEMCRITMEPCRILYNTTFFPKFLRCNETLFPTKCTNGARGMKFNGTGQCLSPLVPTDTSASYYPGIEGCGVRCKDPLYTDDEHRQIHKLIGWAGSICLLSNLFVVSTFFIDWKNANKYPAVIVFYINLCFLIACVGWLLQFTSGSREDIVCRKDGTLRHSEPTAGENLSCIVIFVLVYYFLTAGMVWFVFLTYAWHWRAMGHVQDRIDKKGSYFHLVAWSLPLVLTITTMAFSEVDGNSIVGICFVGYINHSMRAGLLLGPLCGVILIGGYFITRGMVMLFGLKHFANDIKSTSASNKIHLIIMRMGVCALLTLVFILVAIACHVTEFRHADEWAQSFRQFIICKISSVFEEKSSCRIENRPSVGVLQLHLLCLFSSGIVMSTWCWTPSSIETWKRYIRKKCGKEVVEEVKMPKHKVIAQTWAKRKDFEDKGRLSITLYNTHTDPVGLNFDVNDLNSSETNDISSTWAAYLPQCVKRRMALTGAATGNSSSHGPRKNSLDSEISVSVRHVSVESRRNSVDSQVSVKIAEMKTKVASRSRGKHGGSSSNRRTQRRRDYIAAATGKSSRRRESSTSVESQVIALKKTTYPNASHKVGVFAHHSSKKQHNYTSSMKRRTANAGLDPSILNEFLQKNGDFIFPFLQNQDMSSSSEEDNSRASQKIQDLNVVVKQQEISEDDHDGIKIEELPNSKQVALENFLKNIKKSNESNSNRHSRNSARSQSKKSQKRHLKNPAADLDFRKDCVKYRSNDSLSCSSEELDVALDVGSLLNSSFSGISMGKPHSRNSKTSCDVGIQANPFELVPSYGEDELQQAMRLLNAASRQRTEAANEDFGGTELQGLLGHSHRHQREPTFMSESDKLKMLLLPSK
What is the function of this protein?
Segment polarity protein required for correct patterning of every segment.  G protein-coupled receptor which associates with the patched protein (ptc) to transduce the hedgehog (hh) signal through the activation of an inhibitory G-protein.  In the absence of hh, ptc represses the constitutive signaling activity of smo through fused (fu).  Essential component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required to activate Cad99C-dependent endosome formation, norpA-dependent Ca2+ mobilization and p38 MAPK, which are essential steps in the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794).
What are the official names of this protein?
Protein smoothened, dSMO, SMOH, Smooth.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPRL1_MOUSE
Sequence: MALKKKLNFLWTLVLYLIASRLPKAFGKDLPRVPTITDPKFIDAFLNIHNELRRKVQPPAADMNQLFWDQQLAKLAKAWTRECKLAHNPCIKQRYECLEDYDFIGENIYLGRIETQPEDVVINWYNESKYFNFDFNTCSEMCGHYTQVVWAKTVKIGCAVSNCPNLKGFSAGLFVCNYSPAGNFIGFRPYTRGDSCSMCGQKTCENSLCRPMNRKTPHHKAACHVLVLGFILQSLL
What is the function of this protein?
Required for optimal fertilization at the stage of sperm-oocyte fusion, plays a role in optimizing acrosome function, the translocation of IZUMO1 during the acrosome reaction and the fertilization process (PubMed:20219979, PubMed:31672133).  Component of epididymosomes, one type of membranous microvesicules which mediate the transfer of lipids and proteins to spermatozoa plasma membrane during epididymal maturation.  Also component of the CD9-positive microvesicules found in the cauda region.
What are the official names of this protein?
GLIPR1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Cell membrane; Peripheral membrane protein; Extracellular side. Membrane raft. Secreted. Note=Located in the connecting piece of elongated spermatids and sperm (PubMed:20219979). Also located in the apical region of the sperm head after sperm capacitation (PubMed:20219979). Weakly attached to the cell membrane and later secreted into the extracellular space (PubMed:20219979). Located on sperm equatorial segment and neck (By similarity). Associated with epididymosomes from the caput and cauda epididymis (By similarity).
Protein: CYSA_BURCE
Sequence: MGITVRNLQKRFGDFTALDNVSLDFPPGELVALLGPSGCGKTTLLRVIAGLEHADAGQVVLQGLDVASVGARDRQVGFVFQHYALFRHMTVFENVAFGLRVKPRRERPSEAAIREKVHELLKLVQLDWLAQRYPSELSGGQRQRIALARALAVEPKVLLLDEPFGALDAKVRKELRGWLRRLHDDLHISTIFVTHDQEEALEVADRIVVLNRGHVEQVGSPQDVYDHPQSAFVYEFLGAANRLPGTVAGRGFVAEGAAAPTEVD
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CB042_BOVIN
Sequence: MEPNSLRTKVPAFLSDLGKATLRGIRKCPRCGTYNGTRGLSCKNKTCGTIFRYGARKQPSVEAVKIITGSDLQVYSVRQRDRGPDYRCFVELGVSETTIQTVDGTIITQLSSGRCYVPSCLKAATQGVVENQCQHIKLAVNCQAEATPLTLKSSVLNAMQASPETKQTIWQLATEPTGPLVQRITKNILVVKCKASQKHSLGYLHTSFVQKIGAKSLPERRFFCSCQTLKSHKSNASKDEAVQRCIHFFACICAFASDETLAQEFSDFLNFDSSGLKEVIVPQLGCHSESPVSACESTASKPKKRKKEEVSGAQTNSSLLPPDTVSSNLRKSGLKKPVVASSLKRQACGQLLDEAQVTLSFQDWLASVTERIHQTMHYQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFIRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVESIAETYGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVAEYQDQRPPLDQPLELAPLTTITFP
What are the official names of this protein?
Uncharacterized protein C2orf42 homolog.
Protein: RXRG_XENLA
Sequence: MHLATETAPSMATYSSTYFNSSLHAHSTSVSSSNLAAMNSLDTHPGYMGNSLNGPRSMTTNMNSMCSPGNNIGLPYRVIASSMGPHSLPSPTILNYPGHESPPFNILNNVSCSEDIKPPPGLSSLGSPCMNNYSCNSPGALTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLVYTCRDSKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRSREKSDTEAESTSSTSEEMPVERILEAELAVDPKIEAFGDAGLPNSTNDPVTNICHAADKQLFTLVEWAKRIPYFSDLPLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHNAGVGSIFDRVLTELVSKMKDMDMDKSELGCLRAIVLFNPDAKGLSNAAEVEALREKVYATLESYTKQKYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPHQIS
What is the function of this protein?
Receptor for retinoic acid.  Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes.  The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5.  The high affinity ligand for rxrs is 9-cis retinoic acid (By similarity).
What are the official names of this protein?
Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DADA_ACIB5
Sequence: MRVIVLGSGVIGVASAYYLARQGAEVTVLDRQSGPAEETSFGNAGQISPGYSTPWAAPGIPFKAVKWMFQHHAPLAINLDGSMWQLQWMAQMLKNCNPQSYAVNKERMMRVAEYSRDCLRELRKDTGIHYENRAKGTLQLFRKEAQMEAVQRDISVLEECGVSYELLNGNELGRVEPALANAQDKLVGGLHLPNDETGDCYLFTNALAQIAKELGVNFQFNQNVEKLIVEGDQIKGVQVNGKVLTADRYVLAFGSYSRDFLKPLDLQLPVYPVKGYSLTIPIVDPAFAPQSTVLDETYKIAITRFDQRIRVGGMAELSGFNLGLNEDRRATLQMVTQDLFPGGDMAQASFWTGLRPMTPDSTPIIGATRFKNLFLNTGHGTLGWTMACGSGKLISDIVLNHKTDISTDGLSIQRYSHAHAA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: MURA_RICFE
Sequence: MQKLIIHGGKPLKGSINISGAKNAVLPIMAASILTDKLHITNVPKLTDVSTMKDLLRSHGADIKILEHPDEFELIINTGNINNFTANYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCAIGARQVDLHIAVLKAMGATIEIEDGYINASSKGRIKGTHFVFDKVSVGATINAILAAVLAEGETVLFNCGREPEIVDLCNCLIKMGADIAGVGTSEITIKGKDSLNKASYKVLSDRIEAGTYMFAAAITKGDVKICGIDYHIIENIALKLIETGLKVVQINNGVQVTYEGKLNSVDLETNPYPGFATDLQAQFMSLMTLSSGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGVEMLKGAEVMASDLRASVSLILAGLSTNSKTVLHRIYHLDRGFQDLEKKLSNCGADIKRV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELP6_XENLA
Sequence: MFPELNSLLGVTTDTLTLGKFTLLCDSNTDGSFLVHHFLSYYLRAGCRVCFVALVQSFSHYNIVAQKLGVNLSSAKDEGQLVFLEGLKSYTDLLFGDKSEAEETNPLCFLRAGSDLRPLYSFVSAALAPSAGQPWKCPVLILDDLSVLLSLGVTSLQVLDFMHYCRATVCTQYKGNVLCLVHGAEESGDEENELVLRSLSHQSHLILQAEGLSTGFCKDVHGQLKIIRGAVSSGKRGKNQPEIYQYKIQDKHVAFFARGLSAAVL
What is the function of this protein?
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity).  The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).
What are the official names of this protein?
Elongator complex protein 6, Protein TMEM103.
What is the protein family that this protein belongs to?
Belongs to the ELP6 family.
Protein: PIGA_HUMAN
Sequence: MACRGGAGNGHRASATLSRVSPGSLYTCRTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLKVYYLPLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSSFSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTPDPFRRHDSITIVVVSRLVYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRERYQLHDRVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLPENLIILCEPSVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDRVSVEAVLPMDKRLDRLISHCGPVTGYIFALLAVFNFLFLIFLRWMTPDSIIDVAIDATGPRGAWTNNYSHSKRGGENNEISETR
What is the function of this protein?
Catalytic subunit of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis.
What are the official names of this protein?
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, GlcNAc-PI synthesis protein, Phosphatidylinositol-glycan biosynthesis class A protein, PIG-A.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: CAIA_ECO5E
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROP1_MESAU
Sequence: PQTDKQVCIPPELPELLKTQPPDLIQWAAEYFGAMSRGEIPPVRLIIHADELAQMWKTLKIVCEVLSCDHDGGPPRIPFSTFQFLYTYIAEVDGEISSSHVSRMLNYIEQEVIGPDGLIKVNDFTQNPR
What is the function of this protein?
Important for male fertility.  With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.
What are the official names of this protein?
Ropporin-1, Rhophilin-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the ropporin family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=In the sperm tail, found in the principal piece and in the cytoplasmic droplet located at the distal end of the midpiece. Inner surface of the fibrous sheath.
Protein: RL21_LACJO
Sequence: MYAVIKTGGKQYKVAKGDSVFVEKLEVKPGDEVTFDEVILVNDGKSTKIGTPVVEGAKVVAKVEKQGKEKKVVTFKYKPKKHSHTKYGHRQPYTKVTIESIEA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: KPTA_ECOL5
Sequence: MAKYNDKELAETSKFLSFVLRHKPEAIGIVLDREGWADIDKLILCAQKAGKRLTRALLDTVVATSDKKRFSYSSDGTCIRAVQGHSTSQVAIAFIEKTPPQFLYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKRGIPFWQAENGVWLTSTVAVEFLEW
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: SCX1_ANUPH
Sequence: MKTIPLLFLLFIYFECDGKFIRHKDESFYECGQLIGYQQYCVDACQAHGSKEKGYCKGMAPFGLPGGCYCPKLPSNRVKMCFGALESKCA
What is the function of this protein?
Sodium channel (Nav) specific neurotoxin.  Causes impairment of movement and mild paralysis in crickets at a dose of 0. 5 ug per animal.  A dose of 0. 8 ug per cricket causes clear flaccid paralysis.  A dose of 1. 0 ug per cricket causes death within 2 hours.
What are the official names of this protein?
Phaiodotoxin.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU3_BUCUA
Sequence: MTRKYRIAVLPGDGIGPEVMREAYKILNILKDDFSLPLEIKEFNIGGAAIDQEGVALPKKTLLGCENSDAILFGSVGGKKWDNLPINQRPERASLLPLRKHFNLFANLRPAQLYSELKNLSPLRSNIIKNGFNILCIRELTGGIYFGKPTGRLKKNNIEYAFDTEIYYNYEINRIAHLAFQLSQTRNYKVCSIDKSNVLNSSILWREIVKKVSKHYPDVHLSHLYIDNATMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASLNEKKFGLYEPAGGSAPDIEGKNIANPIAQILSLSMLVRYSMNLKKIADKIDQSVISVLKKGYRTADISNNNDYLKTNEMGDVIASALISGE
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK_XANCP
Sequence: MKIAILSRNSKLYSTRRLIEAGRTRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDAVIPRIGASVTRYGTAVLRQLEFMGTYTPNPSDAILRSRDKLRAHQLLASQGIDMPVTVFGDNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASASRGVVEALRGLYANFIVQEFIGEAEGADLRCFVVGDRVVAAMRRQAADGDFRSNLHLGGTAAMAEASPQEQDVAVRSARALGLAVAGVDLIRSQRGPLVLEVNSTPGLEGVEGVCGVDVAGTIIQHLEQAIR
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: LKHA4_ARATH
Sequence: MAPIDPHSFTDSSHPLTTHVALSLYLDFNTSIIHGSALLTLSSAFSGELSLDTRCISIAMVLDPLTLEPIPYSVSTTPDRIRGTEVVVVLSGQSSLLIVYSTSPSASALQWLSPLQTFSKLHPYVYTQCQAIHARSIFPCQDTPAARIRYDVVMNIPNSLSAVMSARHVRRRLAVPEEAKHLEAGSLGSSLWCGEDRVVEEFAMEQPIPPYLFAFAVGELGFREVGPRTRVYTESAAIEVLDAAALEFAGTEDMIKQGEKLFGDYEWERFDLLVLPPSFPYGGMENPRMVFLTPTVIKGDATGAQVVAHELAHSWTGNLITNINNEHFWLNEGFTTYAERRIVEVVQGADIATLNIGIGWRGLTDEMERFKDNLECTKLWNKQEGVDPDDVYSQVPYEKGFQFVLRIERQIGRTAFDEFLKKYIATFKFKSIDTNTFLEFLKANIPGIEKEINLQLWTEGVGIPEDAYEPVSTIYTKIISLAKEFKEGKMPSEDDVAEWNGQEWELYLENLPKSCEPSQVMALDKRYRLAESKDYEVKVSFLQLAVTSKCREYHGEVKKTLKEVGRMKYLRPLFTALAQSGGTEEKQLAKQVFAEARETYHPIAQGVVESILSKYI
What is the function of this protein?
Aminopeptidase that preferentially cleaves di- and tripeptides.  Also has low epoxide hydrolase activity (in vitro).  Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
What are the official names of this protein?
Leucine aminopeptidase, Epoxide hydrolase, Leukotriene A-4 hydrolase homolog, LTA-4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_CLAM3
Sequence: MAERVVLAYSGGLDTSVGIGWLKDATGKEVVALAVDVGQGGEDMEVIRQRALDCGAVEAVVVDAKDEFADDYIVPALKANALYQKRYPLVSGLSRPLIAKHLARVAHELGANSVAHGCTGKGNDQVRFEAAVAALAPDLTSIAPVRDLALTRDKAIVYANEHDLPIEQSKKSPYSIDKNVWGRAVETGFLEDPWNGPIEDLYEYTQDPDVLRDATEVTITFEAGVPVAIDGVRYSPLRIVQELNAAAGAHGIGRIDVVEDRLVGIKSREVYEAPAAMTLIEAHEELESLTIERDLGRYKRGVEKDWANLVYDGLWFSGLKRSLDAFIEDSQRHVSGDIRMTLRGGRAVVTGRRSESSLYDFDLATYDTGDTFDQSLSKGFIELWSLPSKISARRDLAVEQAALAADPAPAAE
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_SYNWW
Sequence: MRIFIDSANIEEIKEINGMGFLAGVTTNPSLVAKEKKDYKGLIREISMLVDGPISAEVIALDYQAMVQEGEELASIHPNVVIKIPLCEEGLKAIHALKQKGIATNATLVFSANQALLAARAGASYVSPFIGRVDDTGNDGLTLLDDIVQIFDQYMVETEVIAASIRHPMHVVASAKIGSNIATIPYQVIKQMVKHPLSDAGIEKFMSDWKKAF
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_CHLTB
Sequence: MLILDRSSPQIFISNEQQDVSIDLQSAQRLVVLFLELQKVSTDQVYVYFLDDTALAQLHDEQFSDPSLTDTITLPIDKPGIASFPHVLGEAFVSPKAAMRFLEQYTEDQLYHEISRYVVHSLLHMLGYDDQTDEDKRIMQEQEDVSLSFLAEHQALLRPAV
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEFG_DICDI
Sequence: MDKINNENDKINISIKAPIGNIEDNNNNSNNNSNNNSVSNSNNNSSISINSGSNTPTNSKNRGIKIFDLDDPFTSKRLSGFFSPESLAELSKLQLNDTDNNDNLTTTTTTTTTTTTTTTTTNTITSKNNSPNTSPLLSSTTISSITSGAPIKKRFERIPSGLSHVTNHYDDDDDDESSSSEEDFDSTELVCRPNKTSSTTATTTTTTTSVSPLTSSFVMRRPSSPSPPPSCSSPTLSPSLSATRRLSGNLVKVATDSDNQSLEPCNNKTIVDNNDNDNDNNNNHNNNNNNNNNNNSTEDISIKPICNKTFLDLDEKIYLKIFGYLFAEDLCSINRVSKHLCNIINNQQLWKDLFSIYIKIYSEPSDIYIWDEDLYSIYNNNNNNNNNNNNNNNNNNNNNNSNISNNNNNINNSNGNNNPYFTGGVSNSSIGAIGGSIGSSAGSNIALKLRSNTSIPIIERGRSNTIAMPTPTFINEINMLNSNNSVNNNNNISNNNTINSNNAGVIINPSGTVNNNINNINSSNSINSSSSSGSNINLSNNNSSTIHGSYISSNLILNSVLRKFTPTTSVPSTNEVTDFIESCHHFPSKLLICKLVQRYLVPREFQRHLSDIDWVKMVERPIQLRVGKLLKKVIDQKKVNFDYGTMLILRSFIRGYIQSTSDMAKGLIVGLQKKQVLKVFDISRVSDILLIKIFRNLDSIKDLSVCQRVSKRWNKAIAISSLWEQLYLNYRKKLHHEGDINIWDDPSLHTVEYLYEFFDQIQPSPQQQQQQQQQQQQQQQQQQQPQLQTNESNNNNEDIKQNDNNNNNSNNNGLNNLQKLIEENLEGSNLSNGGNSGSSFSPFNPLSGSNGGSSFGPFGSGGGGGSNSNIGGSSNQLNSSSGGGGSGFLAMASGGSSVSSVTSTPSTISTNCTPTGGSTTNSPNFQSPMVSSSTVLPPPIPFSPNLSSPRSMSISLSSPPPLPNKPPELKLPDSSLSPNSSFNNNLSSTSISIPSTPTTTPSSSLLTFIPPNTTSTTTTTSTTNITSTTMPISAATTTTTTTTSTTSTIIQPIQPIPPVNNNGSQSDLSKISDLNANPNTTTTTTTNTIESSSSSSSITNNNENIIEPIKSPQPSMINVQKLMNLNQLVDKLTSITVATEISEVNACLATYRTFISTSQLVEKLFQRYHIPRASNIKSILDWKQRIETPIQVKVCKVFKKLIDDHFDDFNGTIIELFKVFLLHIIDKQSPLTNHLIRSFSRKLSGENGSTGSVIGITGGKSSRKGGGSGSGSGSGGGSGSSIIGGAVGGTIKASQSKIGRMMSVRKAQQFNDIISLPAEEIAKQLTLIEFEIFGKIQSSEFLNQSWAKEKTFHLAPNIRASIDRFNTVTKWVCTIILKEEKIRTRTKIMSKLLKVAKNLRSYSNFHTLMAILSGLNEIHIYRLKFTQQELKPKIQKISSELQTLMSVEGNHEAYRTELSNVDPKQSCIPYLGVYLKDLTFIQDDTNKKGDGINIKQSLNLYNILKTIQNFQKNPYSFEEFPKIKETLLNLPVWTEDNLYRVSMQREPRNCKRSDLI
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP.
What are the official names of this protein?
Ras guanine nucleotide exchange factor G, RasGEF domain-containing protein G.
Protein: DNAJ_STRA1
Sequence: MNNTEFYDRLGVSKDASQDEIKKAYRRMSKKYHPDINKEAGAEEKYKEVQEAYETLSDTQKRAAYDQYGAAGANGGFGGFDGGGFGGFEDIFSSFFGGGGMRNPNAPRQGDDLQYRVNLSFEEAIFGAEKEVSYNRESSCHTCSGSGAKPGTSPVTCQKCHGSGVINVDTQTPLGTMRRQVTCDVCQGSGQEIKEKCPTCHGTGHEKKTHKVSVKIPAGVETGQQIRLTGQGEAGFNGGPYGDLFVIINVLPSQQFERNGSTIYYTLNISFVQAALGDTIDIPTVHGAVEMSIPAGTQTGKTFRLRGKGAPKLRGGGQGDQHVTVNIVTPTKLNDAQKEALHAFAEASGDKMVHPKKKGFFDKVKDALDVD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_ECOSM
Sequence: MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDVLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKVAINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: DNAA_PEDPA
Sequence: MPNYIDLWNNIKNSFEKDDSMSKASFGAWVETAEPISLENHIMKIKVLSSLHRDYWTKHLIEKFVEYAYQFTDQDITPEFVTEDEFKTQQAERSATSKKETKASTEDTQLNSRYTFDTFVIGSGNQMAHAAAMAVSDEPGVLYNPLFFYGGVGLGKTHLMHAIGHQLLENDPKTRVKYVTSEAFTNDFINSIQKNKTEEFHEKYRNVDLLLVDDVQFFADKEATQEEFFHTFEALYNAQKQIVLTSDRLPNEIPKLQERLVSRFKWGLSIDITPPNLETRIAILREKAQADNVEIPDETLEYIANRIDSNIRELEGAMARIQAYAKLQNAAITTDLASDALRSLNFGSNLSHITIPMIQDKVAKYFHVTVADLKGKKRMKSIVIPRQIAMYLSRELTESSLPKIGTEFGGKDHTTVIHSFDKIKAELEKDEELARQVGDLKSELKP
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.