PharMolix/UniProtQA huggingface dataset:
Protein: BIOF_ANADF
Sequence: MARAPLDWIDRELEALEAKGLRRALEPLASPQGPVVEVGGRRLVNLCSNDYLGLAADPRLRSAAAEAAEREGAGSGASRLVAGDLPVHGALERAIAGHAGTEAALLFGSGYHANAGVPPALVGRDDAVFSDVLNHASIVDGCLLSRAKLVRYRHADVQELADLLAGTPARRKLVVTDAIFSMDGDAAPLREIAGLCDRHGAMLYVDEAHATGVLGPRGGGLAEALGVADRVDVHMGTLGKALGAAGAFVAGERRLVDLLVSRARTFVFTTAPAPAASAAALAALAIVEAEPERRARVLALAARMRVGLERLGFDVSRVAAPIFPVILGDEARAVAASRALRERGFFVRAIRPPTVPRGTSRLRVTLTAAHGEAQVDAFLGALEEVLRVPGGGAPRVL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: RS9_MYCPN
Sequence: MEKQSYYGLGRRKSSSAKVYLTPTQDKGKITVNRRDPSEYFPNKLVIQDMEQPLDLTDLKKNFDINVVVKGGGFTGQAGAIRLGIVRALLQFNPELKKILKSKKLTTRDKRVKERKKFGLYGARRAPQFTKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: SURE_METS4
Sequence: MRILVTNDDGIHAPGLKVLEEIARGLSDDVWVVAPETDQSGVSHSLSLNDPLRLRKVAETRFAVKGTPSDCVIMGVRHILKERGPDLVLSGVNRGQNVAEDVTYSGTVAGAMEGTILGVRSIALSQAYGAGGRAHVKWQTASHHGARTIRRILEAGIEPGILVNVNFPDCEPEAVEGIAVVAQGMRNQQLLAIDERVDGRGNPYFWLAFAKARFEPGHGTDLKAIAENRIAVTPLRLDLTDEPTLTRFAQALG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_STAEQ
Sequence: MSIEWLSEKLSEQGIELSNTQKEQFQKYYKLLVEWNKKMNLTSITDEHDVYLKHFYDSIAPSFYYDFNGQLSLCDIGAGAGFPSIPLKIVYPELKVTIVDSLNKRIQFLNHLAAELGLEDVSFVHDRAEIYGKGVYRESYDIVTARAVARLTVLSELCLPLVKKGGQFLALKSSKGEEELQEATFAINILGGNVKETHTFELPENAGERQMIIIDKRRQTSKKYPRKPGTPNKSPLVES
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_LACP7
Sequence: MVERNLRKTRTGKVVSDKMDKTIVVAVVDNVKHPLYGKIVKRTYKLKAHDENNECQIGDRVKVMETRPLSKDKRWRLVEIIEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CSR1_ASHGO
Sequence: MTQTAAPGRVQTLTKEQEKVLKQVWVHLFQFWGIDVDGSAVLTAKEPEPAAPSGKGRKLLGLFGKRKDATGAARKESNGKAAAKVYDAEKVEDSDAEKEKPTPQKVEGLEEMYELLKELDGAAVSKEFWSMLRCDYPDNLLLRFVRARKWDINKAMIMMAHSLRWRLNEGKPEDIVFGGERGAQKADKKGIVKQLELGKATVRGFDKNGCPIVYVRPRLHHAADQTEAETSEYSLLIIEQARLFLKEPCDTATILFDLSGFSMANMDYAPVKFLITCFEAHYPECLGKLFIHKAPWIFPPIWNIIKNWLDPVVAAKIAFTKTAADLEEFIPAEQIPLELGGKDEYNFDGFVMPDGSADTKLSDEKGKAAVLEEREAIIKRFIDATISWIESTSDEESAKWLEKKIDLSKELSENYSKLDPYIRSRSFYDVNGTLKV
What is the function of this protein?
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity.  May also regulate post-Golgi membrane-trafficking events and have a role resistance to oxidative stress (By similarity).
What are the official names of this protein?
Phosphatidylinositol transfer protein CSR1.
What is the protein family that this protein belongs to?
Belongs to the PITP family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome.
Protein: HSLU_ECO8A
Sequence: MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQTIIIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GE_HHV1F
Sequence: MDRGAVVGFLLGVCVVSCLAGTPKTSWRRVSVGEDVSLLPAPGPTGRGPTQKLLWAVEPLDGCGPLHPSWXSLMPPKQVPETVVDAACMRAPVPLAMAYAPPAPSATGGLRTDFVWQERAAVVNRSLVIYGVRETDSGLYTLSVGDIKDPARQVASVVLVVQPAPVPTPPPTPADYDEDDNDEGEGEDESLAGTPASGTPRLPPPPAPPRSWPSAPEVSHVRGVTVRMETPEAILFSPGEAFSTNVSIHAIAHDDQTYTMDVVWLRFDVPTSCAEMRIYESCLYHPQLPECLSPADAPCAASTWTSRLAVRSYAGCSRTNPPPRCSAEAHMEPVPGLAWQAASVNLEFRDASPQHSGLYLCVVYVNDHIHAWGHITISTAAXYRNAVVEQPLPQRGADLAEPTHPHVGAPPHAPPTHGALRLGAVMGAALLLSVLGLSVWACMTCWRRRAWRAVKSRASGKGPTYIRVADSELYADWSSDSEGERDQVPWLAPPERPDSPSTNGSGFEILSPTAPSVYPRSDGHQSRRQLTTFGSGRPDRRYSQASDSSVFW
What is the function of this protein?
The heterodimer gE/gI serves as a receptor for the Fc part of host IgG.  Dissociation of gE/gI from IgG occurs at acidic pH.  May thus be involved in anti-HSV antibodies bipolar bridging, followed by intracellular endocytosis and degradation, thereby interfering with host IgG-mediated immune responses (By similarity).
What are the official names of this protein?
Envelope glycoprotein E, gE, gE-1.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein E family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host cell junction. Host Golgi apparatus, host trans-Golgi network. Note=During virion morphogenesis, this protein probably accumulates in host trans-Golgi where secondary envelopment occurs. The heterodimer gE/gI then redistributes to cell junctions to promote cell-cell spread later in the infection.
Protein: YQGF_CUPNH
Sequence: MPDAVGRELPRDGTVLAFDYGEKKIGVALGNFITREARALTILPNITVEGRFEAVAALIQEWNPVQLIVGMPVNPEGGEQPSMKLARRFGNQLNGRFGLPVEWVDERYTSRAASMAGARRGELDAEAARIILQQYFDQFPL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BJSB1_TRINI
Sequence: MRVLVLVASLGLRGSVVKDDTTVVIGKDNMVTMDIKMKELCILKLLNHILQPTMYDDIREVAREWVIEENMDKYLKTDVVKKFIDTFKMGMLPRGEVFVHTNELHLEQAVKVFKIMYSAKDFDVFIRTACWLRERINGGMFVYALTACVFHRTDCRGITLPAPYEIYPYVFVDSHIINKAFMMKMTKAARDPVMLDYYGIKVTDKNLVVIDWRKGVRRTLTEHDRISYFTEDIDLNTYMYYLHMSYPFWMTDDMYTVNKERRGEIMGTYTQLLARLRLERLSHEMCDIKSIMWNEPLKTGYWPKIRLHTGDEMPVRSNNKIIVTKENVKVKRMLDDVERMLRDGILTGKIERRDGTIINLKKAEDVEHLARLLLGGMGLVGDDAKFMHMMHLMKRLLSYNVYNFDKYTYVPTALDLYSTCLRDPVFWRLMKRVTDTFFLFKKMLPKYTREDFDFPGVKIEKFTTDKLTTFIDEYDMDITNAMFLDDVEMKKKRSDMTMVARMARLNHHPFKVTVDVTSDKTVDCVVRIFIGPKYDCLGRLMSVNDKRMDMIEMDTFLYKLETGKNTIVRNSLEMHGVIEQRPWTRRILNNMIGTVGTISKTVDVESWWYKRHRLPHRMLLPLGRRGGMPMQMFVIVTPVKTNLLLPNLDMNIMKERKTCAGASVSTRCRSGFPFDRKIDMTHFFTRNMKFTDVMIFRKDLSLSNTIKDVDMSDMMMKKDDLTYLDSDMLVRWSYKAVMMMSKDDMMRM
What are the official names of this protein?
Basic juvenile hormone-suppressible protein 1, BJHSP1.
What is the protein family that this protein belongs to?
Belongs to the hemocyanin family.
Protein: ALL12_ACTDE
Sequence: NRQPSKYGLEETI
What are the official names of this protein?
Allergen Act d 12.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: PACRG_HUMAN
Sequence: MVAEKETLSLNKCPDKMPKRTKLLAQQPLPVHQPHSLVSEGFTVKAMMKNSVVRGPPAAGAFKERPTKPTAFRKFYERGDFPIALEHDSKGNKIAWKVEIEKLDYHHYLPLFFDGLCEMTFPYEFFARQGIHDMLEHGGNKILPVLPQLIIPIKNALNLRNRQVICVTLKVLQHLVVSAEMVGKALVPYYRQILPVLNIFKNMNGSYSLPRLECSGAIMARCNLDHLGSSDPPTSASQVAEIIVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGENAFINIKYVVPTYESCLLN
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity).  Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin).  Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited.  May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease (PubMed:14532270).
What are the official names of this protein?
Parkin coregulated gene protein, Molecular chaperone/chaperonin-binding protein, PARK2 coregulated gene protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: SYC1L_HUMAN
Sequence: MAGKLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQEALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGEAGPELPRARDEEDPEPPVAAPDAL
What is the function of this protein?
May be involved in meiosis.
What are the official names of this protein?
Synaptonemal complex central element protein 1-like, Meiosis-related protein.
What is the protein family that this protein belongs to?
Belongs to the SYCE family.
Protein: RT07_WHEAT
Sequence: MGDFDGEQKELIKKLVNFRMIDGKRTRVRAIVYKTFHRLARTERDVIKLMVDAVDNIKPICEVVKVGVAGTIYDVPGIVARDRQQTLAIRWILGAAFKRRISYRISLEKCSFAEILDAYRKRGISRKRRENLHGLASTNRSFAHFRWW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 18S rRNA where it nucleates assembly of the head domain of the small subunit.
What are the official names of this protein?
Ribosomal protein S7, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GL123_ORYSJ
Sequence: MASSNFFLLIPLIALVTTQAMASDPSPLQDLCVADKNSPVRVNGFPCKDAKDVSVDDFFLAANLDKPMDITKSKAGSNVTLINVMKLAGLNTLGISMARIDYAPKGQNPPHTHPRATEILSVIEGSLYVGFVTSNQANGENKLFTKTLNKGDVFVFPEGLIHFQFNPSYDKPAAAIVALSSQNPGAITIANAVFGSNPPISDDVLAKAFQVDKKAVDWLQAQFWENNHN
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Putative germin-like protein 12-3.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: PAL2_ORYSI
Sequence: MECENGRVSANGMSGLCVAAPRADPLNWGKATEEMTGSHLDEVKRMVAEYRQPLVKIEGASLRIAQVAAVAAAGEARVELDESARERVKASSDWVMNSMMNGTDSYGVTTGFGATSHRRTKEGGALQRELIRFLNAGAFGTGTDGHVLPAEATRAAMLVRINTLLQGYSGIRFEILEAIAKLLNANVTPCLPLRGTITASGDLVPLSYIAGLVTGRENAVAVAPDGSKVNAAEAFKIAGIQGGFFELQPKEGLAMVNGTAVGSGLASTVLFEANILAILAEVLSAVFCEVMNGKPEYTDHLTHKLKHHPGQIEAAAIMEHILEGSSYMKHAKKLGELDPLMKPKQDRYALRTSPQWLGPQIEVIRAATKSIEREINSVNDNPLIDVSRGKALHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLGNPVTNHVQSAEQHNQDVNSLGLISSRKTAEAIDILKLMSSTFLIALCQAVDLRHIEENVKSAVKSCVMTVAKKTLSTNSTGDLHVARFCEKDLLKEIDREAVFAYADDPCSHNYPLMKKLRNVLVERALANGAAEFNADTSVFAKVAQFEEELRATLPGAIEAARAAVENGTAAIPSRITECRSYPLYRFVREELGTKYLTGEKTRSPGEELNKVLVAINEGKHIDPLLECLKEWNGEPLPIC
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHO16_ARATH
Sequence: MKFGKDFSSEWQQAYVDYKYLKTLVKDINRFKRKTNLHGGQISLSSTVLEIEDGITTATIQVSSTASQRYETTFLMTAEKGGEYELVFFRRLDDEFNKVEKFYREKVDEVVKEAAVLNKQMDALIAFRLKMKEESTVEMARFALHGVVSPAELAKNPSMKVHMEAIEEGGSSRAGRRSDEDDYYTDEEDHNDVFFTPANNLSKMKSSSSAFIEVLDSIKINNTKEALQSNTKSVLKVSNHTELKFSRDNLRKIEEKLICAFVEFHRKLWYLKSYSFLNVLALSKILTKYDKITSRDAAKSYMKMVDKSCLGSSDEVMKLMENVEATFIKQFTNGNRTKGMNILRPKPKRERHRLTFSTGFLGGCMFSLIVALVAIVRTRNILQDDGQKQYMNTMFPLYSLFGFIMLHMTMYAANIYFWRQYRVNYSFIFGFKQGTELGYKQVLFVGFSIGALALLCVLANLDMETDPKTKDYQALTELLPLFLLIAMFVVLVVPFNIFYRSSRFFFLTTLFHMLAAPLYKVTLPDFFLADQLCSQAQTLRSIEFYICYYGWGDFKQRKNTCKDSQVFNTFLFIVSAFPFFSRFLQCMRRMLEEKNIEQGYNGFKYIVIVVAVCLGMAYEVDDEKDRQIIWRLLGGITSAMAVVFCTYWDLVYDWGLLNRTSKNPWLRDNLLIPHKEVYVLAMILNVVLRFAWMQTVLDFKFESIHTQTVVAVVASLEIIRRGIWNFFRLENEHLNNVGKYRAFKAVSLPFNYEVDH
What is the function of this protein?
May transport inorganic phosphate (Pi).
What are the official names of this protein?
Phosphate transporter PHO1 homolog 6, Protein PHO1 homolog 6, AtPHO1;H6.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS14Z_THEKO
Sequence: MAKADYNKRKPRKFGKGARRCMRCGQYGPIIRIHGLMLCRHCFREVAPKLGFKKYE
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: CYB_SORUN
Sequence: MTNLRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGVCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSALPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLCSDADKIPFHPYYTIKDILGVLLLILALTSLVLFSPDLLGDPDNYTLANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAVVPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVIMPITSLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DNAT2_DROME
Sequence: MSAITIRAMTIGDYEEVEAFLAVHFFKQEPLMLIPQEDPKQSEVSSAEAELHRSLIPQDLSLVAVDGERIVGVVLAGELVPEDLEREYQEAEQKEITCLLDKIHKFLAGIERQANIFKHYGVERALYLYMLGVDVSIRRQRVGTRLVEATIELGRQRGFPVVTSTCSNQNSKRLMTALNMECILTKDYADYKDEHGEIVLRASEPHTSASVVAIRL
What is the function of this protein?
Catalyzes the formation of long-chain N-acylserotonins and N-acyldopamines, which are important cellular signaling lipids (PubMed:24444601, PubMed:31385627).  Catalyzes in vitro the formation of various N-acetyl-2-arylethylamines such as N-acetyltryptamine and melatonin (PubMed:11098219, PubMed:26476413).
What are the official names of this protein?
Arylalkylamine N-acetyltransferase-like 2, AANAT2, Arylalkylamine N-acyltransferase-like 2.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. AANAT subfamily.
Protein: DCUP_MOUSE
Sequence: MEANGFGLQNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREERDLERLRDPAAAASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGSSSTMAQAKRWLYQRPQASHKLLGILTDVLVPYLIGQVAAGAQALQLFESHAGHLGTELFSKFALPYIRDVAKRVKAGLQKAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARERVGKAVTLQGNLDPCALYASEEEIGRLVQQMLDDFGPQRYIANLGHGLYPDMDPERVGAFVDAVHKHSRLLRQN
What is the function of this protein?
Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway.  Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme (By similarity).  In vitro also decarboxylates pentacarboxylate porphyrinogen I (PubMed:8661721).
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACM4_BOVIN
Sequence: MKQSVKKPPPPGDTTVRGELPNGKLEEAPPPVLPPPPRPMADKDTSNESSSGSATQNTKERPPTELSTTEATTPATPAPPLQPRTLNPASKWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANV
What is the function of this protein?
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.  Primary transducing effect is inhibition of adenylate cyclase.  May couple to multiple functional responses in cell lines.
What are the official names of this protein?
Muscarinic acetylcholine receptor M4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM4 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: HGH1_DROPS
Sequence: MEVVSELVQFMQPNQRLDLKAVALTHVLGLTGSAEGKAAILALDDMLMAIFGLTFDDNHTVAKDAVLSLINLTADEECATKVFHLAKRIQPPFAIVEVAATQISDEQSPLADPWSMVLSNLTRVESLVHEILDILERGEQTLPRLAKAFAQLDYNKKKARLHYLAPIFCNLTQVARGRELCCHARYQLLEKLLPFASYEENVVRRGGTIGILKNVCFDAVYHGVILGEDDNILVAILQPLCGPEEFSDEENDMLPIELQYLPESKTRETDPDLRKMLLECLLQLCSTRRSREILRAKGVYEILREYHKWEARVGLDRDCLLACENVVDILIKKEEEIGLDNYKNVEVPAEQAEKFVQEDVEYVKSLLD
What are the official names of this protein?
Protein HGH1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HGH1 family.
Protein: RECO_CERS5
Sequence: MLEWRDEGALLSVRRHGESAAIIEVFTASHGRHLGVVRGGASRRHAPVLQPGAQLDLTWKARLDDHMGAFTVEPLRARTGIFGDRLALAGLNAICAMLHVVLPEREPHVGLWRESIELMDALAAPGWPAAYLRWEMRLLEEAGFGLDLTRCAVTGSREDLAFVSPRTGRAVGRAAAGDWADRLFPLPLALLGQGPASGPEVRQGLAITGHFLARELPLAGRPLPEARARLIDLLARG
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RL21_DESAH
Sequence: MYAVIKTGGKQYKVQEGDTLRVEKLEGTENGEIEFNDVLMFSDGENVTLGQPAIEDAIVKGHILEQGKGKKVLIFKFKRRKGYRNLRGHRQQYTAVKIDSILV
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RS14Z_GEOTN
Sequence: MAKKSMIAKQKRTPKFKVRAYTRCERCGRPHSVYRKFKLCRICFRELAYKGQLPGIKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RL10_BRUSU
Sequence: MDRAEKREFVAWLNGAFKESGSVVVAHYTGLTVAQMSDLRSKMRDAGGSVKVAKNRLAKIALQGTESEGIADLFTGQTVVAYANDPITAPKVAVEFAKANDKLVILGGAMGATTLNADGVKSLASLPSLDELRAKLVGMIQTPAQRLAVLTSAPASQIARVIGAHARKNEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: HLTF_RABIT
Sequence: MSWMFKRDPVWKYLQTVQYGVHGNFSRLSYPTFFPRFEFQDIIPPDDFLTSDEELDSVLFGTLRGHVVGLRYYTGVVNNNEMVALQREPNNPYDKNAIKVNNVNGNQVGYLKKELAAALAYIMDNKLAQIEGVVPYGANNAFTMPLQMTFWGKEENRKAVLDQLKKHGFKLGPAPKTLGFSLESGWGSGRAGPSYSMPVHAAIQMTTEQLKTEFDKLFEDLKEDDKTQEMEPAEAVETPLLPHQKQALAWMVSRENSRELPPFWELRNDLYYNTITNFSEKDQPENVHGGILADDMGLGKTLTAIAVILTNFHDGKPLPVERMKKNQVKKECNSSESDKPGRKDTIKKTDGLSKEGSRYSEEPSISDVKKNKYSMSELSSSQPKRKKIAVQYIESSDSEEIEISELPQKMKGKLKNVQSETKRVKVGPSKIKEDTAFACALTSSASTTTKKILKKGASAQRVQRKLMFEERPRTTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVYYGPDRIRDPALLSKQDIVLTTYNILTHDYGTKGDSPLHSIRWLRVILDEGHAIRNPNAQQTKAVLDLEAERRWVLTGTPIQNSLKDLWSLLSFLKLKPFVDREWWHRTIQRPVTMGDEGGLRRLQSLIKNITLRRTKTSKIKGKPVLELPERPVFIQHITLSDEERKIYQSVKSEGKATIGRYFNEGTVLAHYADVLGLLLRLRQICCHTHLLTNTVSSSGPSGNDTPEELRKKLIKKMKLILSSGSDEECAICLDSLTVPVITHCAHVFCKPCICQCIQNEQPHAKCPLCRNDIHGDNLLECPPEELACDSEKKSNMEWTSSSKINALMHALIDLRTKNPNIKSLVVSQFTTFLSLIETPLKASGFVFTRLDGSMAQKKRVESIQCFQNTEAGSPTIMLLSLKAGGVGLNLCAASRVFLMDPAWNPAAEDQRFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNTKRELAAGAFGTKKNANEMKQAKINEIRTLIDL
What is the function of this protein?
Has both helicase and E3 ubiquitin ligase activities.  Possesses intrinsic ATP-dependent nucleosome-remodeling activity.  This activity may be required for transcriptional activation or repression of specific target promoters (By similarity).  These may include the SERPINE1, to which this protein can bind directly.  Mediates repression by c-Rel through a DNA-looping mechanism.  Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA (By similarity).  Transcriptional regulator that mediates the ability of prolactin to augment progesterone-dependent transcription of the SCGB1A1/uteroglobin gene through a bipartite progesterone receptor half-site/overlapping Y-box combination (-38/-26) where progesterone activation is attenuated by nuclear factor Y binding.  Regulation also involves two GC-rich sequences in the proximal promoter (positions -162/+90) and a RUSH/SMARCA3 site (positions -616/-611) in the 5'-untranslated region.
What are the official names of this protein?
Helicase-like transcription factor, RING-type E3 ubiquitin transferase HLTF, RUSH-1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3, Sucrose nonfermenting protein 2-like 3.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Cytoplasmic and nuclear localization in the presence of prolactin. Nuclear localization is stimulated by progesterone.
Protein: Y1275_METVS
Sequence: MKKIISIKGTEKEVIEICERISKMGIDYSFDAKANYSENKAYNSARIKIFGEDKNKLVEDYKNILSIIEHVHNKYNVDVKGLYEYKLSDLKYPVNKDLVLDTLSALKINFKYLKDENVIKCELKVEELNDILKNILEIYSELNVYKLGSKPVKNVLALASYITGNDVNILLEKGLEKELFREENEKIVLNKDIDLTRKELLSVKK
What are the official names of this protein?
Uncharacterized protein Mevan_1275.