PharMolix/UniProtQA huggingface dataset:
Protein: EFTU_LACLM
Sequence: MAKEVYDRSKPHVNIGTIGHVDHGKTTLSAAISKVLSDKGYSKATDFASIDAAPEERERGITINTAHIEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLSRQVGVKYLIVFLNKADLVDDEELMELVEMEVRDLLSEYDFPGDDIPVIAGSALGALNGEPQWVAKVEELMDIVDEYIPTPERDTDKPLLLPVEDVFSITGRGTVASGRIERGTVKVGDEVEIVGIKEETKKAVVTGIEMFRKTLTEGLAGDNVGALLRGIQRDEIERGQVIAKPGSITPHKLFEGEVYVLSKEEGGRHTPFFDNYRPQFYFHTTDVTGSVKLPEGTEMVMPGDNVHIDVELIHPVAIEQGTTFSIREGGRTVGSGIVAEIKA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCRL2_HUMAN
Sequence: MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV
What is the function of this protein?
Receptor for CCL19 and chemerin/RARRES2.  Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors.  Plays a critical role for the development of Th2 responses.
What are the official names of this protein?
C-C chemokine receptor-like 2, Chemokine receptor CCR11, Chemokine receptor X, Putative MCP-1 chemokine receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYY_BIFA0
Sequence: MAHVIDFKEAGFDSVLDELEWRGLISQSTDRDRLAHTLNGEPVHYYCGFDPTAPSLHIGNLVQLIIMRHLQEAGHHPIALVGGATGLIGDPRQSGERILNPKDIVEQWCERLRIQIGGILEQEGSNPVTFVSNYDWTATMNVLDFLRDIGKNFRVGTMISKDIVARRLNSEEGISFTEFSYQVLQGNDYLYLYDHYDCVLELGGSDQWGNLTSGLDLIHKVRGVNVNVMASPIITDANGKKFGKSEGNAVWLDPNMLSVYKFYQFWLNRPDVEMASLLKAFTFLPKAEIERLVEATDTNPGAREAQRVLAWEVTSLVHGDEPTRKAIDASASLFGRGGDLADIDLETLESVLDGLKVENEAGEKVFAQALPGDRIAQAGVSAGLFKSISEARKTIKSGGVYVNNVRVEDEEQLLGDGDFLKGRFVVLRRGKKALGVVARS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPM_SALHS
Sequence: MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNADWQFDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRLLLQRLSRFISHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: PORB_HORVU
Sequence: MALQAATSFLPSALSARKEGAAKDSAFFGVRLADGLKLDATSLGLRTKRVNTSSVAIRAQAAAVSAPTATPASPAGKKTVRTGNAIITGASSGLGLATAKALAESGKWHVIMACRDYLKTARAARAAGMPKGSYTIVHLDLASLDSVRQFVKNVRQLDMPIDVVVCNAAVYQPTAKEPSFTADGFEMSVGVNHLGHFLLARELLEDLKASDYPSKRLIIVGSITGNTNTLAGNVPPKANLGDLRGLAAGLNGVGSAAMIDGAEFDGAKAYKDSKVCNMLTMQEFHRRYHEETGVTFASLYPGCIATTGLFREHIPLFRLLFPPFQKYITKGYVSEEEAGKRLAQVVSEPSLTKSGVYWSWNKNSASFENQLSEEASDTEKARKVWELSEKLVGLA
What is the function of this protein?
Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
What are the official names of this protein?
Protochlorophyllide reductase B, chloroplastic, PCR B, NADPH-protochlorophyllide oxidoreductase B, POR B.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYY_AYWBP
Sequence: MSFYEELKWRNLIKDCNNEIQVKELLDNNQVKFYCGFDPTSHSLTVGHLIQITMILLMQRQGHLPVILVGGATGLIGDPKETEERKLLSLENSLQNAKSIESQLKTILLNKQVEFVNNYQWLSQIDIISFLRNYGKFFNINYMLSKHVVAKRLASGISFTEFSYMILQSLDFHHLYKNHKVRLQLGGSDQWGNITSGLEIIRKLEKKSDALGVSTPLLLNSDGTKFGKSEKRVLWLNPLMTSPYEIYQYFLNVSDKEVINYLKMLTLIPKKGILELEKKTLENPQKRLAQKALTQSIINLIHSSDILQECIKTNQILFSNAKKESFQEKDFILLQKTLFCHSIKEDILLVDALVQTKLATSKSEAREFIKDNTIKLFNQKIKSLDFIITKENTLFGKYILLKKGKKNNALIVF
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX1AB_DINQU
Sequence: LPLDDLSDT
What is the function of this protein?
May have antimicrobial properties, like most ant linear peptides.
What are the official names of this protein?
U1-poneritoxin-Dq1b, U1-PONTX-Dq1b, Peptide Dq-987, Poneratoxin.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1612_LISIN
Sequence: MKISFHGQSCIKIITGNTTILVDPFISGNEKCDLKAEEQMPDFIVLSHGHDDHVGDTVEIAKNSGATVICNADLASFLAVEDGLENIAPMHIGGKRQFDFGQVKLTQAFHGSQTVRDGRIINLGFPTGIVFTIEGKNIYFAGDTGLFSDMKLIGELNPLDVAFLPIGDNFTMGPEDAAIAARFLQAKLVIPMHYNTFPLIEQDPHQFVASLDEGISGKVLEIGEGIEI
What are the official names of this protein?
UPF0173 metal-dependent hydrolase lin1612.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: TGFR1_HUMAN
Sequence: MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTVKSSPGLGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM
What is the function of this protein?
Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3.  Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis.  The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2.  Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4.  The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes.  This constitutes the canonical SMAD-dependent TGF-beta signaling cascade.  Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.  For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis.  Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation.
What are the official names of this protein?
TGF-beta receptor type-1, TGFR-1, Activin A receptor type II-like protein kinase of 53kD, Activin receptor-like kinase 5, ALK-5, ALK5, Serine/threonine-protein kinase receptor R4, SKR4, TGF-beta type I receptor, Transforming growth factor-beta receptor type I, TGF-beta receptor type I, TbetaR-I.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Cell surface. Membrane raft.
Protein: Y390_STRZT
Sequence: MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHAARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKFNELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINVIKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYASPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMNDLGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKSADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEELGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK
What are the official names of this protein?
UPF0371 protein SPT_0390.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: PAN2_HUMAN
Sequence: MNFEGLDPGLAEYAPAMHSALDPVLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVGVPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGSDDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYLLDENEDMHSLLLTDSSTLLVGGLQNHIIEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRTFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAFLRFIPTYTSRLAIISQSGQCQFCEPTGLANPADIFHVNPVGPLLMTFDVSASKQALAFGDSEGCVHLWTDSPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLSLIPVPLTTDTLLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPNPRTRLRNQIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWNRFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKRSICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPEGQTSPKNAAVFSSVLAL
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP).  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  Also acts as an important regulator of the HIF1A-mediated hypoxic response.  Required for HIF1A mRNA stability independent of poly(A) tail length regulation.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit PAN2, Inactive ubiquitin carboxyl-terminal hydrolase 52, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
Protein: TM156_HUMAN
Sequence: MTKTALLKLFVAIVITFILILPEYFKTPKERTLELSCLEVCLQSNFTYSLSSLNFSFVTFLQPVRETQIIMRIFLNPSNFRNFTRTCQDITGEFKMCSSCLVCESKGNMDFISQEQTSKVLIRRGSMEVKANDFHSPCQHFNFSVAPLVDHLEEYNTTCHLKNHTGRSTIMEDEPSKEKSINYTCRIMEYPNDCIHISLHLEMDIKNITCSMKITWYILVLLVFIFLIILTIRKILEGQRRVQKWQSHRDKPTSVLLRGSDSEKLRALNVQVLSAETTQRLPLDQVQEVLPPIPEL
What are the official names of this protein?
Transmembrane protein 156.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ECTB_STRCO
Sequence: MTITQPDLSVFETVESEVRSYCRGWPTVFDRAVGSRMYDEDGHEYLDFFAGAGSLNYGHNNAVLKRALIDYLERDGVTHGLDMSTTAKRRFLETFQNTILRPRDLPYKVMFPGPTGTNAVESALKLARKVKGRESIVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDNYFDGTVEDFIWFERLLEDQGSGLNKPAAVIVETVQGEGGINVARAEWLRALADLCERQDMLLIVDDIQMGCGRTGAFFSFEEAGITPDIVTVSKSISGYGMPMALTLFKPELDVWEPGEHNGTFRGNNPAFVTATATLEAYWADGSAMEKQTRKRGEQVEQHMIAITEENLADVKEYRGRGLVWGLEFHDKDRAGRVAKRAFELGLLIETSGPESEVVKLLPALTITPDELDEGMKTLARAVRETA
What is the function of this protein?
Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.
What are the official names of this protein?
Diaminobutyrate--2-oxoglutarate transaminase, DABA aminotransferase, Diaminobutyrate--2-oxoglutarate aminotransferase, L-2,4-diaminobutyric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: SYT_PORGI
Sequence: MIKITFPDGNFREYEAGITGWDIAGSISPRLQQDVLAAGVNGQVWDLHRQINEDAEVKLFKWDDAEGKHAFWHSSAHLMAEALEELYPGIKFGIGPAIENGFYYDVDPGEGISIKDADLPAIEKRMQDLAARKETIIRRDIAKADALRMFGDKDDQYKVELISELADGTITTYTQGGFTDLCRGPHLPNTGYIKAIKLLSVAGAYWRGDEKRKQLTRIYGISFPKKKMLDEYLELLEEAKKRDHRKIGKELELFAFSQNVGAGLPLWLPRGTQLRLRLEDFLKQIQKHFGYQQVITPHIGNKNLYITSGHYAKYGQDSFRPINTPQEGEEFMLKPMNCPHHCEIFKITPHSYRDLPIRLAEFGTVYRYEQSGELHGLTRVRGFTQDDAHLFCRPDQLKEEFCKVMDIIFIIFKALDFKNFEAQISLRDKVNREKYIGSEENWERAERAIIEACEEKGLPAVIEYGEAAFYGPKLDFMVKDALGRRWQLGTIQVDYNLPERFDLEYTGEDNKKHRPVMIHRAPFGSMERFVAVLIEHTAGKFPLWLTPDQVVVLPVSERFNEYAHRVAKELNQRDIRVQVDDRNEKVGRKIRDNELKRIPYMLIVGENESREEEVSVRKQGEGDMGIMKITTFAELIEKEVDDMISAWRKDYQN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_AZOVD
Sequence: MTAVIGVRELGLLDYLPAWQAMQRFTGQRGAQTPDELWLLEHPPVFTQGQAGKAEHLLFPGDIPVVQVDRGGQVTYHGPGQLVGYLLLDVRRSGMGVRELVSRIERSLIELLAGYDVEAHARPDAPGVYVGEMKIASLGLRIRNGRSFHGLALNVDMDLAPFQRINPCGYAGMLMTQLKDQARGPVEFAEVRSRLRAQLAAQLGYAEAKTLTGGIESI
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXH_PSE14
Sequence: MILLISDLHLEQDRPDITRAFLDLLAGRAREAEALYILGDFFEVWIGDDAMSPFQLSICKALRALSDSGTRIFLMHGNRDFMIGKGFCKAAGCTLLSDPSVVQLNGERVLLMHGDSLCTRDEGYIRMRRYLRHPLTLFILRHLPLGTRHKLARKLRNESRAQTRMKANDIVDVTPDEVPRIMQQFGVRTLVHGHTHRPAIHKLQIGDQAARRIVLGDWDRQGWVLQVDEQGFSLNSFDFVPETTALLN
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OHRL_STAAS
Sequence: MAIHYETKATNVGGRKGHVYTDDRALDIDIVSPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
What are the official names of this protein?
Organic hydroperoxide resistance protein-like.
What is the protein family that this protein belongs to?
Belongs to the OsmC/Ohr family.
Protein: IF2_SERP5
Sequence: MTTDVTVKSLAAEIQTPVDRLVQQFADAGINKSETDSVTQHEKEALLAHLNREHGSAPGKLTLQRKTRSTLNIPSTGGKSKSVQIEVRKKRTYVNRDTPEAQQAEAAEQAQREAEEQAQRAAEELAKREAEAKRAAEEQAKREAAEIAKRNSAEKEKVTNQHTDEMTKPAQAEKARREAEAAELKRKAEEEVRRKVEEDAKRVAEEARRMAEEKGEEWAAAEKASAAVETADYHVTTSQHARAAEDENDAKVEGERRTRTRGGKATKQKKGNKLSESKADREEARAVTRGGKGKRKPSTLQQGFNKPAQVVNRDVVIGETITVAELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEALMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVAAGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPLVVAVNKIDKPEADPDRVKQELSQYGVMPEEWGGEAQFVHVSAKAGTGIDELLNAILLQSEVLELKAVRSGMASGVVIESFLDKGRGPVATVLVQEGTLNKGDIVLCGFEYGRVRAMRDELGREVTSAGPSIPVEILGLSSVPAAGDEATVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTDGEVSELNIVLKSDVQGSCEAICESLLKLSTDEVKVKIVGSGVGGITETDATLAAASNAIILGFNVRADASARRVIEAESLDLRYYSVIYNLIDEVKQAMSGMLAPEYKQQIIGLAAVRDVFKSPKFGAIAGCMVTEGNIKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRVGDMIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VA0E_ASHGO
Sequence: MSFYTVVATFLSVVLASAVFWVLAPKENQTVWRSTIILSMSMMFLMWAVTYLSQLHPLVVPRRSDLRPEFAE
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit e, V-ATPase subunit e, Vacuolar proton pump subunit e.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase e1/e2 subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: SMYD1_MOUSE
Sequence: MTIGSMENVEVFTSEGKGRGLKATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECAAIKKYGKVPNENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEHFGEEEQKELRVDVDTFLQYWPPQSQQFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLHLSEERRRQLKKQYYFDCSCEHCQKGLKDDLFLAAKEDPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNLYVLRLLSIASEVLSYLQAYEEASHYARRMVDGYMKLYHHNNAQLGMAVMRAGLTNWHAGHIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRMQTEMELRMFRQNEFMYHKMREAALNNQPMQVMAEPSNEPAPALFHKKQ
What is the function of this protein?
Methylates histone H3 at 'Lys-4' (H3K4me).  Acts as a transcriptional repressor.  Essential for cardiomyocyte differentiation and cardiac morphogenesis.
What are the official names of this protein?
Histone-lysine N-methyltransferase Smyd1, CD8b-opposite, SET and MYND domain-containing protein 1, Zinc finger protein BOP, m-BOP.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSLBB_HUMAN
Sequence: MRLIQNMCTIAEYPAPGNAAASDCCVGAAGRRLVKIAVVGASGVGKTALVVRFLTKRFIGDYERNAGNLYTRQVQIEGETLALQVQDTPGIQVHENSLSCSEQLNRCIRWADAVVIVFSITDYKSYELISQLHQHVQQLHLGTRLPVVVVANKADLLHIKQVDPQLGLQLASMLGCSFYEVSVSENYNDVYSAFHVLCKEVSHKQQPSSTPEKRRTSLIPRPKSPNMQDLKRRFKQALSAKVRTVTSV
What are the official names of this protein?
Ras-like protein family member 11B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
Protein: RMIL_AVEVR
Sequence: MEAVIKDLIRDQGVRGEGGSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGIGEWAVHLLKGLLLGLVVILLLVVCLPCLLQCVSSSIRKMIDNSLGYREEYKKLQEAYKQPERRA
What are the official names of this protein?
Serine/threonine-protein kinase-transforming protein Rmil.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Protein: YEF3_YEAST
Sequence: MPVSVITTVLACLWLSYRLYKFLTIPVSSIVSTLKIKTPPATKVSIDKIATDSVTIHWENEPVKAEDNGSADRNFISHYLLYLNNTQLAIFPNNPNSLYTCCSITGLEAETQYQLDFITINNKGFINKLPSIYCMTKAREANEALKTRKWRRNTITSSTAMQPRNSKSEPAPLPSHYSSVSLSTFSSNITNSATSNNGSNLPAYTSLTTLKDLDSFSIDDLKKILICAQEDLHDVLSQQTSLLQDFQESKLELELELDNLKTHWSHEIDLRKSLKSNIKSLENSKLLTDLKIEKLNKKIDKSKEKISKMRNDMQKWSQEDTELLSKDTIKEKYFKLLNESNASVANINKEIESLQNEISKMEESNKRLNASKKSLITSIVVNANVENDKPIASGELSAVLKKLNDFTLEKNGFLSNAGEEFLSKLNADSSLIKMIKQELSIDQELEANWKLQRSNLLKKISALENQFNEMSLNNRNLKTKLMVQPYKNNGDSLAATNSNNSAEKNRSSGSIQLPLSNNMSRTGSIDLISNNNKSINNSNADSAPPLRLHNPVSYSPSNEPIQPSSSLLSQLTQDTDNRSMLSNHISSNNENKQQPSSYSHALPTTATANATATATATNGHSRSNLWTTAQFAQPSHQQVSTELDQAFEYDNANHLISGLQNMIYDETDYPDNISNYSKGFTTDELDNYWTKQQPQVRSTNESLFSTTGTPMSSYKANPVISPYSSSHLRQTSNATNTNPMHPQSLLAATLNDPSLQSFVRSGSFYSAPQPANSLQNNINGNETENISPRISSDFNLLVPNLSPRLSNDVPIVPGNNTTLTPSHSNILTMNHQPTADNITRRSFHASSPPFNSIWNSNTNQLSPPLEEQYHLDVPVGPKVPAKEPSPKPSHKRNQSNSSISSAWSKFKHKSASSPANADTDIQDSSTPSTSPSGRRMSKLLSKSGMNNLFNPHSHDS
What are the official names of this protein?
Uncharacterized protein YEL043W.
Protein: ZNT6_HUMAN
Sequence: MGTIHLFRKPQRSFFGKLLREFRLVAADRRSWKILLFGVINLICTGFLLMWCSSTNSIALTAYTYLTIFDLFSLMTCLISYWVTLRKPSPVYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALCFNLFTMLSIRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHVIPMPLLKGTDDLNPVTSTPAKPSSPPPEFSFNTPGKNVNPVILLNTQTRPYGFGLNHGHTPYSSMLNQGLGVPGIGATQGLRTGFTNIPSRYGTNNRIGQPRP
What is the function of this protein?
Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway (PubMed:15994300, PubMed:19366695, PubMed:19759014).  As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis (PubMed:15994300, PubMed:19759014, PubMed:35525268).
What are the official names of this protein?
Zinc transporter 6, ZnT-6, Solute carrier family 30 member 6.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Found in vesicles.