PharMolix/UniProtQA huggingface dataset:
Protein: HIS4_SHISS
Sequence: MMIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVGSTAVKSPERVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDINDVAALRGTGVRGVIVGRALLEGKFTVKEAIACWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGB1_ASPVP
Sequence: METVLSLLNEFGFERTVEPLSDPIVVHAVPGSGKTTLIKQALIRNNNIEAVTFGVPEKANIHGTYIKKARQGQRGRGNYSILDEYLSGEYSTGFNCLFSDPYQNHGDCLRAHFIGRCSHRFGRQTVQILRDLGYNIASSKEDIVEKKNIFQLIEPEGVIICLEKGVEDFLKWHSVEYKFPCQVRGATFDIVTFIHEKPLEELVGPDLFVALTRHRSKLVLVSN
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Increases plasmodesma size exclusion limit.  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity).
What are the official names of this protein?
Movement and silencing protein TGBp1, 25 kDa protein, Silencing suppressor P25, Triple gene block 1 protein, TGBp1.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp1 protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: Y655_FRAT1
Sequence: MAGHSKWANIKHKKAKEDAKRGKIFTKLIREITVAARLGGGDKDANPRLRAAIATALANNMSKDTIERAVVKGAGGDESANVEEVRYEGYGPGGVAIIVDCMTDNRNRTVGEVRHAFTKSGGNLGTDGSVAYMFTKRGIISFAPGVDEDALMEVALEAGAEDIITHEDGSIDVYTDPHDFSDIQEVLIEKGFNSENAEVTFDAETKAELDTETAEKVMALIDKLEDLDDVQNVYSNANFTQELIEQIG
What are the official names of this protein?
Probable transcriptional regulatory protein FTF0655.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGKA_CRIFA
Sequence: MLLSTQSIPIKKSVDDIWPVAGKRVLIRVDFNVPTSSGGIDDDFRIRSAIPTIRRIVDQGGICILISHLGRPTGVDYDTAHAEQEKRQTPVQLPNSRGKTAFFSGLRGDAKATILAWSSQREKAATLSNPYGSGKTAVFARLPEEEKRRLLLRFMSEHKEELFPQLGSAGYEKEFSLEPVAVKLAELLDQHVYFGHDCLGAQADIAKLRCGEVMLLENLRFYTNENSSDERKRMLMARILASYADVYINDAFGTAHRDSASLTGIPRVLQQGAAGYLMEKEISYFSKVLNNPPRPLLAIIGGAKLSDKMQVLENLLDCVDSLFIGGGLAYTFLRSQGYSIGTSHFEEAFVPFAQALPLAGSGRQVRVVLPEDHVCHAHTRPAEAPLTTTSANIPDGYAGLDIGPLTIQSITHLVRQCSSVIWNGPLGMFEMPYYAFGTFSIARVVSQSSAAKGTTSIVGGGDTASAMMKSGEAAHISHISTGGNASLELLEGKVLAAVAVLDNKE
What are the official names of this protein?
Phosphoglycerate kinase, glycosomal, Phosphoglycerate kinase A.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Glycosome.
Protein: AC4CH_ECOL6
Sequence: MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRFEDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLTELKKVIADIYPDQTQFYVIEFKCL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: SYDND_SALTO
Sequence: MIRTHDAGSLRATDAGSTVTLAGWVARRRDHGGVIFVDLRDGSGVAQVVLREEDAHVLRNEYCVRVTGEVTRRPEGNENPELATGEVEVTAEELEVLSEAAPLPLPVDDQIEAGDDVRLRYRYLDLRRSGPASALRLRSAANQIARTVLHERDFLEIETPTLTRSTPEGARDFLVPVRLQPGTWYALPQSPQLFKQLLMVGGMERYYQIARCYRDEDFRADRQPEFTQLDIEMSFVTEDDVIDLGEAIVSRLWRELAGHQITRPIPRITWHEAMARYGSDKPDLRYGVELTELTDYLRGTRFRVFAGAIEAGGYVGAVVMPGGAAQSRKELDGWQDWAKARGAKGLAYVVLDAETGEARGPVAKNLSTEHLAGLADVVGAKPGDAIFFAAGAESRAAQELLGAARVEIARRANLVDESAWAFCWVVDAPMFERVTDREEAGAGGWTAVHHPFTAPNAEWMDRFEEAPDRALAYAYDIVCNGNEIGGGSIRIHRGDVQQRVFDLLGITPEQARDKFGFLLEAFKYGPPPHGGIAFGWDRVCMLLAGADSIREVIAFPKTRGGFDPLTAAPTPITAAQRLEAGVDARPKPEARAQAGTAGPAAPVADPT
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_BIFLO
Sequence: MPEIIIVKNEAEAGEIYGRCVADLIKAKPDAVLGLATGSSPLAAYQALAKIVKDEAIDVSGVRGFALDEYIGLPLTHPESYHATIHRTVVEPLGLDPAKVHVPGDVLNGTPLEDGDKVALAGPAYDRAIEAAGGIDVQILGIGTDGHVGFNEPGSSLASGTRVKTLAEQTRIDNARFFDNDINQVPTHCITQGIGTIMKARHLVLLAFGAGKAEAIEETVEGGVSAFCPASALQMHPHATIIVDEEAASRLRHKDYYRYAYTHKPAWQGI
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ERP44_MOUSE
Sequence: MNPAVFLSLADLRCSLLLLVTSIFTPITAEIASLDSENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDKNQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSNPVHEIQSLDEVTNLDRSKRNIIGYFEQKDSENYRVFERVASILHDDCAFLSAFGDLSKPERYNGDNVIYKPPGRSAPDMVYLGSMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKDDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGPDPTDTAPGEQDQDVASSPPESSFQKLAPSEYRYTLLRDRDEL
What is the function of this protein?
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif.  Inhibits the calcium channel activity of ITPR1.  May have a role in the control of oxidative protein folding in the endoplasmic reticulum.  Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
What are the official names of this protein?
Endoplasmic reticulum resident protein 44, ER protein 44, ERp44, Thioredoxin domain-containing protein 4.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: NHAB_ACTP7
Sequence: MDSSNAIFKSFLGKAPEWYKICIIAFLVINPLIYFFISPFVAGWALVAEFIFTLSMALKCYPLQPGGLLAIEAVFIGMTSAHHVKEEIMANFEVILLLMFMVAGIYFMKQLLLYVFTKLLIVIHSKKILSLAFCLSATFLSAFLDALTVIAVIISVGTGFYGVYHKVASGNSFEDSTDISNDEKIITNKEILEQFRAFLRSLLMHAAVGSALGGVMTMVGEPQNLIIAGQAEWGFVEFLLRVLPVSLPVLICGVITCLLLEHFKIFGYGARLPRRVWGVLARYNLLKEQRMTQQDRVKMGIQALAGIWLVVGLALHLADVGIIGLTIIIICTAFCGITDEHAIGRSFQEPMPFTALIVVFFTVVAVIVDLKLFEPIISYVLSADPHSQLALFYVFNGLLSMISDNVFVGTVYINEAKTALESAIISREQFDLIAVAINTGTNLPSVATPNGQAAFLFLLTSPFAPLIRLSYGKMLYMALPYTIVLSIIGFLSLEFLLPPLTELMSNWGWIITR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLRX2_MOUSE
Sequence: MSWRRAASVGRRLVASGRILAGRRGAAGAAGSGMGNSTSSFWGKSTTTPVNQIQETISNNCVVIFSKTSCSYCSMAKKIFHDMNVNYKAVELDMLEYGNQFQDALHKMTGERTVPRIFVNGRFIGGAADTHRLHKEGKLLPLVHQCYLKKKQEERH
What is the function of this protein?
Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress.  Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress.  Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides.  Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions.  Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex.  Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
What are the official names of this protein?
Glutaredoxin-2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.
Protein: YR160_MIMIV
Sequence: MSISKTLDKNIKQVNGPINVVRLQGKIGSVNKVVYLFMDRHLAVEYQTECDNIFAKDVHMFFADSFKNIGSTGKTYDFFLEKDAEEITPKIPEELNTSKTKYISEVGKMFKKIFKYDPKANRALTSDIFQNTRFHYIDFRGYLYMDIFEPIDMANYVMENIWNKRDLKSEDLNRIAGQLNIVSQQCQLILQIMDSYSNNKNRDKNNSERQYGVRKITPLKYTTVSESYQKTYKQQKQIQIDYIRYFINKIYTKYNDNTIKSKLINRLEYFKNGIRNLNTEVNNIIVDINNIMTEMTSSSGKLVQYNEKWYYGMPYEKEIMYIADLYNKLRNLNGDSVSYIARLIDIYFLRRFLDKDYITNAILYSGANHSLTDIDILVKDFDFKITHVAYSKYPINQITNSVKKAEFGMVNIQPLFDNNEQCSDVTYFPDNFL
What are the official names of this protein?
Uncharacterized protein R160.
What is the protein family that this protein belongs to?
Belongs to the mimivirus R160 family.
What are the subcellular locations of this protein?
Virion.
Protein: UBIB_SALPA
Sequence: MTPGEVRRLYFIIRTFLSYGLDELIPRMRLTLPLRLWRYSLFWMPNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPQIADQLALLQDKVAPFDGRLAKAQIEEAMGGLPVEAWFDDFDIQPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIQADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFENSPMLYIPEVYSDYCSQNMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVKVFFTQVFRDSFFHADMHPGNIFVSHEHPENPQYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEDFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALTRALKEKAPFWVEKMPEIPELVYDSLRQGKYLQHSVDKIARELQVNHVRQSQSRYLLGIGATLLLSGSFLLVNRPEWGLMPGWLMVGGVVVWLVGWRKTR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FBPC_HAEI8
Sequence: MINNPLLTVKNLNKFFNEQQVLHDISFSLQRGEILFLLGASGCGKTTLLRAIAGFEHPNTGEIWLKERLIFGENFNLPTQQRHLGYVVQEGVLFPHLNVYRNIAYGLGNGKGKNSEEKTRIEQIMQLTGIFELADRFPHQLSGGQQQRVALARALAPNPELILLDEPFSALDEHLRQQIRQEMLQALRQSGASAIFVTHDRDESLRYADKIAIIQQGKILQIDTPRTLYWSPNHLETAKFMGESIVLPANLLDENTAQCQLGNIPIKNKSISQNQGRILLRPEQFSLFKTSENPTALFNGQIKQIEFKGKITSIQIEINGYAIWIENVISPDLSIGDNLPVYLHRKGLFYA
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: COBD_SINFN
Sequence: MSIEIFLVLVVALIIDRLVGDPDWLWERLTHPVVFFGKAIGVFDEALNRGADGGWLKMRGVATILILLAASILLGVVLNRLFDVLGAVGFILEAITVAVFLAQKSLADHVRRVADGLRSNGLEGGREAVSMIVGRDPKTLDEPGVCRAAIESLAENFSDGVVAPALWYAVAGLPGLLAYKMLNTADSMIGHKSPKYLHFGWASARLDDLANLPAARLSVFLIAAGARFKRGVEAAKAAIDVAKRDHGFHRSPNSGWPEAAMAGALDIQLAGPRVYGGVTVDEPMINGAGRAIATADDIDAAVAVFYRACTTLAAASAVLVLPFLLL
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBH_THEVB
Sequence: MARRTWLGDILRPLNSEYGKVAPGWGTTPLMAVFMGLFLVFLLIILEIYNSTLILDGVNVSWKALG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: TBA_ENCHE
Sequence: LYCKEHGILPDGRLDQNRMDDESAESFFSQTSVGTYVPRTLMVDLEPGVLESIKTGKYRELYHPGQLISGKEDAANNYARGHYTVGKEIIEPVMEQIRRMADNCDGLQGFLIYHSFGGGTGSGFASLMMDRLAAEFGKKSKLEFSVYPAPKIATAVVEPYNSILTTHTTLDYSDCSFLVDNEAIYDMCRNLGIQRPYYTDINRIIAQVVSSITASLRFPGSLNVDLTEFQTNLVPYPRIHFPLVAYSPMLSKEKAAHEKLSVQEITNACFEPQSQMVRCDTRKGKYMACCLLFRGDVNPKDANTATANVKAKRTNQFVEWCPTGFKVGINSRKPTVLDGEAMAEVSRAVCALSNTTAISEAWKRLNNKFDLMFSKRAFVH
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YM012_YEAST
Sequence: MLFYHCSSFSSSSSSSSSSASTRRLPFGHSWGTWSTDMCSLGCTVYLGKGDTNSKSNSSLPRSRSNEVSSLLMMWPSSSIVVAVAVSSCPSLKQSISSSADNCLILSWRALDHSAGSLEYTARYM
What are the official names of this protein?
Putative uncharacterized protein YML012C-A.
Protein: RL13_PROMT
Sequence: MNKTSVPSPDSIDRQWFLVDAENQTLGRLATEVASVLRGKTKPNFTPHLDTGDFVIVVNAEKIKVTGKKSDQKLYRRHSGRPGGMKVETFKALQSRIPERIVEKAIKGMLPHTRLGRQLFTKLKVYKGSDHPHSAQEPKILSLNSESVTK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TY3H_CAEEL
Sequence: MSSLTNNTFMEEEPRGVTVIATKVAENSKNPRRYSLVHQASCETQHHKGIRRQNTIQHRKQLTDQMRCQKILQQLNDEGIEVIFTANDVTPIEFSIILTSTDPTLSNFVSDILQNMSSAKVQICHVETRGNEASHDVLLACKATKNQLIHSAELLTQNHVALTKFSIFAKKLSDEKNQSQIWFPRHISELDQCSKCITKYEPTTDPRHPGHGDVAYIARRKFLNDQALEFKFGDEIGYVDYTEEEHATWKAVYEKLGDLHLSHTCAVYRQNLKILQEEKVLTADRIPQIRDVNKFLQKKTGFELRPCSGLLSARDFLASLAFRVFQTTTYLRHHKSPHHSPEPDLIHELLGHVPMFSDPLLAQMSQDIGLMSLGASDEHIEKLSTVYWFIVEFGLCKEDGKLKAIGAGLLSAYGELMHACSDAPEHKDFDPAVTAVQKYEDDDYQPLYFVADSIHDALAKLRKYASSMDRPFSVVYDPFTKSIEAIESSADLEKAFSRLSNDLSAITHAADRMKISITM
What is the function of this protein?
Involved in the synthesis of catecholamines, such as dopamine.  Has a role in serotonin signaling.  Required for normal explorative and foraging behavior.  In response to food, involved in promoting the dopamine-mediated suppression of crh-1/CREB1 transcription factor activation in cholinergic SIA neurons (PubMed:19609300).  Modulates male mating behavior by controlling the protrusion of copulatory spicules from the tail of males during hermaphrodite vulval location (PubMed:23166505).
What are the official names of this protein?
Tyrosine 3-monooxygenase, Abnormal catecholamine distribution protein 2, Tyrosine 3-hydroxylase, TH.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell projection, axon. Note=Expressed in dopaminergic axons and axon terminals.
Protein: CBPYA_NEUCR
Sequence: MRISASTVLLGAASAASAASFQNQAQHVLADNFHKAHDAVKPVADSFAHTTLESFEEAFNGMNSQAKALWDEIKLLVPENAFDKPTWFSKPKAAKRRKDWDHVVKGADVQKLWVKGADGEKHREVGGQLDNFNLRVKSVDPSKLGVDKVKQYSGYLDDEENDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFLELGPSSIDKKLRVVSNEYAWNNNASVIFLDQPVNVGYSYSGNAVSNTVAAGKDVYALLTLFFHQFPEYAKQDFHIAGESYAGHYIPVFASEILSHKDRNINLKSVLIGNGLTDPLTQYEHYRPMACGEGGYPAVLSESECRSMDNALPRCQSLIRNCYESGSVWSCVPAAIYCNNQFIGPYQRTGQNVYDIRGKCEDDSNLCYSALGWISDYLNQKDVMDALGVEVEGYESCNFDINRNFLFQGDWMQPFHRLVPGILKEIPVLIYAGDADFICNWLGNKAWSEALEWPGKNGFNKAELEDLSLPKADKEYGKVKSSGNFTFMQIYQAGHMVPMDQPENSLDFLNRWLGGEWFEQ
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: Y1429_HELPY
Sequence: MPILFDCNAIASQVLKDEASALLESVGQFQKPNDLEAIVKLILKSQENGGKLVIVGVGKSALVAQKIVASMLSTGNRSAFLHPTEAMHGDLGMVEKNDVVLMISYGGESLELLNLVSHLKRLSHKIITFTKSPNSSLSKLGDYYLSLKIQKEACPINTAPTTSTTLTLALGDVLMACLMRAKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPSTSFKDALIEMSEKRLGSAILVNEANELVGVLSDGDVRRALLKGVSLKSEVRHFATLKPKSFKNLDALLLEALEFLERHKIQLLVCVDDHNKVLGVLHLHQLLELGLKA
What are the official names of this protein?
Uncharacterized protein HP_1429.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GutQ/KpsF subfamily.
Protein: ACDH_GEOTN
Sequence: MAKVKVAILGSGNIGTDLMIKLERSSHLELTAMIGIDPESDGLKKAKTKGYYVFDGGLKQFLSEASELADLVFDATSAKAHVRHAKALREAGKMVIDLTPAAVGPYVVPSVNLGDYLEESNLNLITCGGQATIPIVHAINRVAQVHYSEIVATIASKSAGPGTRANIDEFTQTTAHGLEAIGGAKKGKAIIILNPAEPPIIMRNAVYALVECEQMDEVAIARSVQETVAYIQSYVPGYRLRTEPLFEGNKVTVFVEVEGAGDYLPTYSGNLDIMTATAIKVAEEWVQHRVKAASV
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: Y1290_MYCTO
Sequence: MLQRSLGVNGRKLAMSARSAKRERKNASTAASKCYVVPPSARGWVHAYSVTATSMLNRRKAILDYLQGAVWVLPTFGVAIGLGSGAVLSMIPVKSGTLIDKLMFQGTPGDARGVLIVVSATMITTIGIVFSLTVLSLQIASSQFSVRLLRTFLRDVPNQVVLAIFACTFAYSTGGLHTVGEHRDGGAFIPKVAVTGSLALAFVSIAALIYFLHHLMHSIQIDTIMDKVRLRTLGLVDQLYPESDTADRQVETPPSPPADAVPLLAPHSGYLQTVDVDDIAEFAAASRYTALLVTFVGDYVTAGGLLGWCWRRGTAPGAPGSDFPQRCLRHVHIGFERTLQQDIRFGLRQMVDIALRALSPALNDPYTAIQVVHHLSAVESVLASRALPDDVRRDRAGELLFWLPYPSFATYLHVGCAQIRRYGSREPLVLTALLQLLSAVAQNCVDPSRRVAVQTQIALVVRAAQREFADESDRAMVLGAAARATEVVERPGTLAPPPSTFGQVAAAQAAASTIRSADRDG
What are the official names of this protein?
Uncharacterized protein MT1328.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VE7_BPV1
Sequence: MVQGPNTHRNLDDSPAGPLLILSPCAGTPTRSPAAPDAPDFRLPCHFGRPTRKRGPTTPPLSSPGKLCATGPRRVYSVTVCCGNCGKELTFAVKTSSTSLLGFEHLLNSDLDLLCPRCESRERHGKR
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: NTM2F_HUMAN
Sequence: MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHRPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPGLRVSGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ
What are the official names of this protein?
NUT family member 2F.
What is the protein family that this protein belongs to?
Belongs to the NUT family.
Protein: SYA_CARHZ
Sequence: MLAREIREKFLKFFESKGHKILPSASLIPANDPSLLWTAAGMVPFKPYFTGAAVPEVRRVTTCQKCLRTPDIESVGRTARHHTFFEMLGNFSFGDYFKKEAITWAWEFVTEHLGISKDKLYITIYLDDDEAFDIWHNVVGVPAERITRLGKDTNFWEIGVGPCGPCSEIYVDLGPEKGCGSPDCGVACDCGRFLEIWNLVFIQFFRDEQGNYTPLEQKGIDTGMGLERVASVLQGVPSNFDTDIFREIMDYAAQILGVKYGYDEKVDVALKVIADHTRAITFAITDGALPSNEGRGYVIRRLLRRALRFGRLLDREEPFLHLVAAKVIEQMGDVYPELREKAEHTLKIIKLEEEKFRETLNQGLSMLAELMERLTQEGKKEIPGHLAFKLYDTYGFPIELTKEIAEEKGFTVDEEGFKQQMEEQRRRAREAREDVDYLSTRDAFLKQLKEELGEVTFVGYEKLSESTEIIAIIKNGQKVESLAAEEEGEIITRVTPFYPEGGGQVADKGEILGDGFKLSVLDVEKPLSDFILHKVKVVEGSVKVGDKATLMVDETTRMSTARNHTATHLLHKALKMVLGEHVNQAGSLVTPERLRFDFTHFEGVSDEDLRKIENIVNEAILRNLLVQIDYTTLDEARKAGVIALFDEKYGDLVRVVKIGEFSAELCGGTHVSSTGVIGFFKILGESSIGAGVRRIEALTGLGALEYVRSLEDTLQKATEPYKCTFAELPEKISNTLKTLKEKDREIEALMQKIASIEVKSLLNSVREIKGVKVLSAIIDGADMEGLRKAYDVVKASLANYVVLLAGVKDGKVNFLAGVDKNLTDKYHAGELVKEAAKIAGGGGGGRPDMAQAGGKNPEKVKEALQVIDAYVQSK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFNG_ANAPL
Sequence: MTCQTYCLFVLSVIMIYFGCSGSALFLGQLQNDIDKLKADFNASNSDVADGNPVFIEKVKNWTERNEKRIILSQIVTLYLEMLKKTDMSKPHIKNLSEQLNTLRNTLSNDYKKFRDLVELSNLQLTGLKIQRKAVSELFSVLQKLVETSTSKRKRSQSPKRCRC
What is the function of this protein?
Produced by lymphocytes activated by specific antigens or mitogens.  IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions.  It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.