PharMolix/UniProtQA huggingface dataset:
Protein: 5HT1B_RAT
Sequence: MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various alkaloids and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling inhibits adenylate cyclase activity.  Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior.  Besides, plays a role in vasoconstriction of cerebral arteries.
What are the official names of this protein?
5-hydroxytryptamine receptor 1B, 5-HT-1B, 5-HT1B, Serotonin receptor 1B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMO_BRASO
Sequence: MQQGSAPNSAPKISFVSLGCPKALVDSERIITRLRAEGYELARKHDGADVVIVNTCGFLDSAKQESLAAIGSAMAENGKVIVTGCMGAEPEQIEQAYPGVLSITGPQQYESVLDAVHRASPPVHNPHLDLVPPQGIKLTPRHYAYLKISEGCNNRCSFCIIPKLRGDLVSRPAADVLREAERLVAAGVKELLVISQDTSAYGLDIKYAESPWKDRSVRARFLDLARELGELGAWVRLHYVYPYPHVDEVIGLMTDGKVLPYLDIPFQHASPNVLKAMRRPAAQDKTLDRIKAWRGACPDLALRSTFIVGFPGETDEDFAYLLDWLDEAEIDRLGCFKYEPVAGATSNALPGQVPDEVKQERWNALMARQQKISARRLKRKVGTRQQIIIDEVGPTVAKGRSKADAPEIDGAVYLSSRRPLRAGEIVTAKIERADEYDLHGTVAGF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_RICAH
Sequence: MSELLLELFSEEIPAFMQKNAEEGYLNIFTQIFAESAIFAKVQVFVGPRRITLYATHLPKVTLPQEEEIKGPSIESPEAAINGFCSAHNVSKLELSTKLINNQLYYFFVKKTKEREIKEILPKIIIEAINKYSWAKSMFWGDYKIKWIRPLRNILCIFDGEVLPLQFGHLTANNITYGHRLTDNKKLEVTDFKDYRNKLLENNVVLERIKREEIIKTGLLELANSQNLNIKEDARLIEEVAGLSEFPVVLLGKIAQKFLELPKEVLIASMRTHQKYFCLFDKTGNFAPYFLFVSNGRFANAELVIQGNEKVLSARLSDALYFYKQDIAKTLESRLGKLEAVTFHAKLGNLREKIEHITDICNYIAPNNKDLITAAKLCKSDLVSEMVGEFPDLQGIMGYYYAKYEGLNEEIAAAIRDHYKPQGLSDNVASGNAALLALADKLDSLVGLMIAGEAPTGSGDPYALRRQALGIIRIILENKLELNLNDLIIFSLKLYGNSADKDLITSFFEERAKFYFKNKYDILLINAVLDLNLVDTQFKLETLKEFLIEDAGKQLLNAYKRASNIIGDQKITGLVDASLFSTQPEKDLFEVVQKISPQIIDSIADKDYKRALNLLSFLLTPITSFFDNVLVNDPDPKIAQNRLSLLQNICELLNKIAKFNRL
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHK_OENEH
Sequence: MNSIEFTLLARRTQNSVISTTSNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAIIDAITKLRKKISREIYEDRIRSQEENRCFTTNHKFHVGPSMHTGNYDPGLLYQLPSTSEIASETFFKYKSSVSAHELVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: PTH_PARPJ
Sequence: MIKLIVGLGNPGAEYTATRHNAGFWLVDQLAREAGTTLRDERRFHGFYAKARLHGEEVHLLEPQTYMNRSGQSVVAVAQFFKILPDEILVAHDELDLPPGSIKLKLGGGSGGHNGLKDITAHLSSQQYWRLRIGIGHPRDLIPESARAGAKPDVANYVLKPPRREEQDVIDASIERGLAVMPQIIKGELERAMMQLHRNP
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL1_SALPA
Sequence: MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSSDRAQQVVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRIIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVYLISPFVGRILDWYKANTDKKDYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEILELAGCDRLTIAPALLKELAESEGAIERKLSFSGEVKARPERITEAEFLWQHHQDPMAVDKLADGIRKFAVDQEKLEKMIGDLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase 1.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_SYNP2
Sequence: MATYLIEVGTEELPADFVAAAIAQLKDRVSHSLTEYFLTPDGIEVYGTPRRLAVLIQGLPDQQADREEEIKGPPAAAAFKEGQPTKAAEGFARKQGVELSALEVRPTEKGDFVFVQKKTLGRPTPEILQELVLGWFTALEGRRFMRWADGDLRFPRPIRWLVSLWNDAVLPLELVNGSGKLEAGRISRGHRILHQGDVTLNNAADYVVTLQQAFVEVNPQVREEKIVAGVKAAAAEIGGEAEMPADLLAEVVNLVEYPTAVVGDIEAEFLELPTEVITTVMVTHQRYFAVRDRQDKTKLLPKFITISNGDPKKSEIIAAGNGRVIRARLADGQFFYRADCDEHLETYLPQLEAVTFQEELGTMRDKVDRIMEISQQIAEQLGLSEADKEIIASTAMLCKADLVTQMVYEFPELQGIMGQKYALVSGEAPAVAEGIFEHYLPRNADDILPQTLAGQVVGMGDRLDTLVSIFGLGMIPSGSSDPFALRRAANAIITVAWDAGLEIDLGELLAQGAKDFVTAHPDKTSPLEALQSFFIQRIQTLLQDEKGIDYDLVNAVLGDDAEYTERALTDLLDVGDRAAFLQSIRDDGQLAKIYATVNRSAKLAAKGNLSTDSLDPTGVINPEKFAQNSERDLYAGLVELVPTTEVARTERDYQKLIDGLAALAPTVERFFDGEDSVLVMAEDPAVRENRLNLLGLLRNHARVLADFGAIVKQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6M_HETBL
Sequence: MSLLFMISVGFSLSSLSMMVIQPLSLGLMLMLMVLCVSGLTSLIIFSWYGYLLFLVYVGGMLVMFMYVISLIPNLIFLSNKVFAYFFFIFFGFMMMNFFVMKELVSVEVKSMSLFDYGYMSMGGSGIIMLYDNFFCYVLLAVILLFVLISVVKICYYCEGPLRVFKFK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CHPA_STRCO
Sequence: MVAAAAATGILSLCGSPALADSHADGAATNSPGAVSGNALQVPVDVPVNACGNTVDVIAALNPAFGNECENASDEKTDGHGGGYGEDASSSSSSSTSASSSGSHADGATEGSPGVGSGNNAQVPVDVPVNLCGNTVDVIAALNPVFGNKCENDAEEPPGYGEEEPPPPTTPPGYGEEEPPPPTHEEPPPPSGEEEPPPPSEEEHTPPAPQTEQPPALAETGSEGTLGAAAAGAVLIAGGAILYRRGRALSGR
What is the function of this protein?
One of 8 partially redundant surface-active proteins required for efficient formation of aerial mycelium; the short chaplins assemble into a hydrophobic, amyloidal fibrillar surface layer that envelopes and protects aerial hyphae and spores, presumably anchored to the long chaplins (PubMed:12832396, PubMed:12832397, PubMed:15228525, PubMed:17462011).  Chaplins have an overlapping function with the surface-active SapB peptide; chaplins are essential on minimal medium while on rich medium both chaplins and SapB are required for efficient aerial hyphae formation (PubMed:17462011).  A minimal chaplin strain capable of forming aerial mycelium/hyphae on minimal medium contains ChpC, ChpE and ChpH.  The strain also has restored rodlet formation on the hyphae surface.  A second minimal chaplin strain with ChpA, ChpD and ChpE makes slightly less robust hyphae (PubMed:18586935).  The long chaplins (ChpA, ChpB, ChpC) are not absolutely necessary for short chaplin localization or rodlet formation, but probably play a role in initiating aerial hyphae development (PubMed:22296345).  Chaplins are also involved in cell attachment to a hydrophobic surface (PubMed:19682261).
What are the official names of this protein?
Chaplin-A.
What is the protein family that this protein belongs to?
Belongs to the chaplin family. Long chaplin subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by at least one of sortases SrtE1 and SrtE2.
Protein: KCY_STRA3
Sequence: MNSINIAIDGPASSGKSTVAKIIAKNLNYTYLDTGAMYRCATYLALQHGYEAQDVSKILGLLAERPISFGKAEDGSQTVFIGTEEVTLAIRQNDVTNNVSWVSAIPEIREELVNQQRRIAKDGAIIMDGRDIGTVVLPDAELKIFLVASVDERAERRFKENQEKGIESDFETLKSEIAARDYKDSHREVSPLKAAEDAIEFDTTGVSIEGVVTFIQEKAEKIIDMKN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_BRUC2
Sequence: MNKPKNSPARKMIAENRKARFNFEILDTLEAGLVLTGTEVKSLRANQANIAESYASFEDGEFWLINSYIPEYTQGNRFNHEPRRLRKLLVSRREMSRLFNSVSREGMTVVPLKLYFNDRGRAKLELALARGKKTHDKRETEKKRDWNREKARLLRDRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: CAS1_BETPL
Sequence: MWKLKIGAETARGDGGGGGGSETWLRSLNNHLGRQIWEFHPELGTQEELQQIDDARRRFWERRFERRHSSDLLMRIQFAKENPSSANIPQVKIKDTEEVREEAVGMTLRRAINFYSTIQADDGHWPGDYGGPMFLIPGLVITLSITGTLNAFLSKEHQCEICRYLYNHQNEDGGWGLHIEGPSTMFGTALNYITLRLLGEPEDGMGAVEKARKWILDHGGATAITSWGKMWLSVLGVYEWSGNNPLPPEVWLCPYLLPCHPGRMWCHCRMVYLPMSYLYGKRFVGPITSTIQSLRKELYTVPYHEIDWNKARNDCAKEDLYYPHPLVQDILWASLYYAYEPIFMYWPAKRLREKALDTVMQHIHYEDENTRYICIGPVNKVLNMLCCWAEDPNSEAFKLHLPRILDYLWIAEDGMKMQGYNGSQLWDTTFAVQAIISTNIAEEYGQTLRKAHEYIKDSQVLEDCPGDLNFWYRHISKGAWPFSTADHGWPISDCTAEGLKAVILLSQFPSETVGKSVDVKRLYDAVHVILSLQNTDGGFATYELTRSYHWLELINPAETFGDIVIDYPYVECTSAAIQALTLFKKLHPGHRREEIENCIAKAAEFIENIQASDGSWYGSWGVCFTYAGWFGIKGLVAAGRTYKNCSSIHKACDYLLSKELASGGWGESYLSCQDKVYTNLKDNRPHIVNTGWAMLALIDAGQAERDPTPLHRAARILINSQMENGDFPQEEIMGVFNKNCMISYSAYRNIFPIWALGEYRCRVLKAL
What is the function of this protein?
Oxidosqualene cyclase converting oxidosqualene to cycloartenol.
What are the official names of this protein?
Cycloartenol synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: GLSA_ENT38
Sequence: MAAVIDNEMLDDILAQVRPLLGQGKVADYIPALASVSGNKLAIAICTVEGQLYQAGDATERFSIQSISKVLSLVAAMRQYEEDEIWQRVGKDPSGQPFNSLLQLEIEQGKPRNPFINAGALVVCDMLQSRLSAPRQRMLEIVRQLSGVSDLSYDANVARSEFEHSARNAAIAWLMKSFGNFHNDVATVLQNYFHYCALKMSCVELARTFLFLADKGYSSHHAQAVVTPMQARQVNALMATSGMYQNAGEFAWRVGLPAKSGVGGGVVAIVPHEMAIAVWSPELDDTGNSLAGVAVLEKLTQRLGRSVY
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: TYB12_ONCMY
Sequence: MSDKPDLAEVSNFDKTKLKKTETQEKNPLPTKETIEQEKQATA
What is the function of this protein?
Plays an important role in the organization of the cytoskeleton.  Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
What are the official names of this protein?
Thymosin beta-12.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FUB2_GIBM7
Sequence: MASELKEYLVIIPDLPDVLAKRQVLLKPHNQDAAPLVKAGRVPFFGSTLAHHSAEGQQVAENGTVMIIKAESEEEIKEIIRKDIFTIEGVWDFGRLSIWPFKSK
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties (PubMed:22652150, PubMed:25372119).  L-aspartate is suggested as fusaric acid amino acid precursor that is activated and further processed to O-acetyl-L-homoserine by cluster enzymes aspartate kinase FUB3 and homoserine O-acetyltransferase FUB5, as well as enzymes of the primary metabolism (By similarity).  The polyketide synthase (PKS) FUB1 generates the triketide trans-2-hexenal which is presumptively released by the hydrolase FUB4 and linked to the NRPS-bound amino acid precursor by NAD(P)-dependent dehydrogenase FUB6 (By similarity).  FUB1, FUB4, and the non-canonical NRPS Fub8 may form an enzyme complex (By similarity).  Further processing of the NRPS-bound intermediate might be carried out by FUB6 and the sulfhydrylase FUB7, enabling a spontaneous electrocyclization to close the carbon backbone of fusaric acid (By similarity).  Dihydrofusaric acid is likely to be released via reduction by the thioester reductase (TR) domain of FUB8 whereupon the final oxidation to fusaric acid may (also) be performed by the FMN-dependent dehydrogenase FUB9 (By similarity).
What are the official names of this protein?
Fusaric acid biosynthesis protein 2.
What is the protein family that this protein belongs to?
Belongs to the YciI family.
Protein: RPN2_YEAST
Sequence: MSLTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMAALIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDEQFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSENVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQLFKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPALLNILSGLPTCDYYNTFLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQNWAKFTATASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGFGRDTTDYLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAAALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLASDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTTVPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALSMILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENADTGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDAFSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERETNKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNGVVVLRDREPKEPVALIETVRQMKDVNAPLPTPFKVDDNVDFPSA
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome regulatory subunit RPN2.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S1 family.
Protein: ENGB_NITOC
Sequence: MNSLYRKAHYQGSAYTLSQLPPDEGMEVAFAGRSNVGKSSAINAITGIGGLARTSKTPGRTQMINFFQLDARRYLVDLPGYGYAKVPEAVKRQWQQTLSAYLEQRRALCGIVLVVDIRRLYQPFDLQMLEWCRSRGLPVRILLTKSDKLKRGAANQALQKATTHLQEVFPMARVQLFSAVNHTGIEAIQAQLDEWLGIGG
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RIMO_PECAS
Sequence: MSNISTPQPRIGFVSLGCPKNLVDSERILTELRTEGYQVVPRYDDAELVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKENQIREVHPKVLEITGPHSYEQVLSHVHQYVPKPTHNPFTSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLDSRPIGSVLDEAKRLVNAGVKELLVISQDTSAYGADVKQRTGFWNGQPVKTSMVSLCEQLASLGVWVRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPKILKLMKRPGAVERTLERIKRWREICPDLTLRSTFIVGFPGETEEDFQMLLDFLKEAKLDRVGCFKFSPVEGAAANELPDQVPEEVKEERFHRFMQLQQAISTQRLQDKIGREVLVLIDEIDEEGAIGRSMADAPEIDGAVYLNGETGVKVGDIVKVKVEHADEYDLWGSRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACT1_NAEPR
Sequence: MEEHQALVIDNGSGMCKAGFAGEDAPRAVFPSLIGRPLQRSIMVGMGNKDAYVGDEAMSKKGILALKYPIEHGIITNWDDMEKIWHHTFYNELRVGPEEHGVLLTEAPLNPKANREKMTQIMFETFRVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILMERGYSFNTSAEREIVRDIKEKLCYIAFDFEGEMKKASESTAVDTSYELPDGNIITIGNERFRCPEVLFQPNFIGMEAAGVHETAFNSIGKCDIDIRKDLYSNVVLSGGTTMFEGIAERMTKELTAMAPASMKIRVVAPPERKYSVWIGGSILSSLSTFQSMWITAEEYEDAGCGIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RHAD_SALPK
Sequence: MQNITDSWFVQGMIKATSDAWLKGWDERNGGNLTLRLDEADIAPFAANFHEKPRYIALSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGVVKIDSDGAGYHILWGLTHDAVPTSELPAHFLSHCERIKATHGKDRVIMHCHATNLIALTYVLENNTALITRKLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAEVLVKIYSMGGMKQTITREELVALGKRFGVTPLASAVALY
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_KLEP3
Sequence: MTITPQQLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVLGLNAALVSLWFVGQNGAMDVTPMIRVDGYAMLYTGLVLLASLATCTFAYPWLEGYKDNKEEFYLLVLIAALGGILLAGANHLAALFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYANSGNLSFLALGKSLADNTLHEPLLLAGLGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYMPVGNSEAVRVVLGLIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILSAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVHAHLWWLVAAVVVGSAIGLYYYLRVAVSLYLSAPEQLNRDAPSNWQYSAGGIVVLISALLVLVLGIWPQPLISIVQLATPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PP4R1_HUMAN
Sequence: MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4.  May play a role in regulation of cell division in renal glomeruli.  The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3.
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 1.
Protein: DPCKG_SULTO
Sequence: MPDSIKKELTRPYGFLFTNNDIFINFILEKKNNRLITVGDVVTSTLYDRNIIPFLSIIDGKTKRQIKVKTVNENVIKVKNEKSTIRFSVMKIIKNLLDKNERATILVDGEEDLLVIPVVIFGRNNDIIVYGQPNAGAVVIINNHFVKIRVKQILEKFYVKKC
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: LLCA1_LACLA
Sequence: MQPYNQSVNEVLEETKSQFEGLSPKEVKNRQAKDGFNELKEKKKTSTWELFIDTLKDPMVIILLLVAFVQLFLGEFVESLVIFIVLMINSVVAVVQTKRAESSLDALRQMSAPSAKVLRNGEKTSIPARELVVGDIVSLEAGDFIPADGRLIDVQNLRVEEGMLTGESEPVEKFSDVIEGEVALGDRKNMVFSSSLVVYGRADFLVTAIAEQTEIGKIAQMLETAEAKQTPLQQKLEKFGKQLGWVILALCALIFAVQILRLFTTNQTADMQKAVLDSFMFAVAVAVAAIPEALSSVVTIVLSVGTNKMAKQHAIMRNLPAVETLGSTSVICTDKTGTLTQNKMTVVDSFLPTQGSKELTDLTQADQKLLLNAMVLCNDSSFSQEGQLLGDPTEVALIAYSDKIGYPYQDLREKSPRLAEFPFDSERKLMSTINDFEGQKTIFVKGGPDVLFNRCNQVFLDGKVQEFTPELKEKFQAQNEAFSQKALRVLAYAYKPVSDNKTELTLTDENDLILIGLSAMIDPPREAVYDSIAEAKKAGIKTIMITGDHKTTAQAIAKDIGLMNEGDMALTGQELDALTEDELRENLEKISVYARVSPENKIRIVRAWQNEHQVTAMTGDGVNDAPALKQANIGIAMGSGTDVAKDASSMILTDDNFVSIVSAVSIGRVVYDNIKKSISYLFSGNLGAIIAIVFALVVGWVNPFTALQLLFINLVNDSVPAIALGMEKAEPDVMEKAPRQLNEGIFANGLMRVILIRGSLIGIAAIISQYVGQKTSPEMGVAMAFTTLILARTLQTFAARSNSQNILKLGFTTNKYVLMAVTFCLALYSLTTLPFLREIFSIPAAFGWSQWIVAAGLAVIAVICMEILKSIKGVFEKH
What is the function of this protein?
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
What are the official names of this protein?
Calcium-transporting ATPase 1, LLCA1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.