PharMolix/UniProtQA huggingface dataset:
Protein: PUR5_PROM0
Sequence: MDYKTSGVDIEAGREFVSEIKQAVEATHTSNVIEGIGGFGGLFRIPIDSFKKPVLVSGTDGVGTKLELAQSKNFHFEVGIDLVAMCMNDIITSGARPLFFLDYIATGKLDKKQLLRVVQGISHGCGENNCSLLGGETAEMPGFYSKNKYDLAGFCVGIVDEDKLINGKKVSENDLIIALKSNGVHSNGFSLVRKIIQNNNQIDKEFEKVSHLNFYDELLKPTKIYNNVINQMLSEDIEIKAMSHITGGGIPENLPRCIPSDFIPYINTSSWQIPTLFKFLKEKGSIPERDFWNTFNLGVGFCLIIDKQFKDAILSICKDYGIDSWEIGKIVRKNDSTISKFLPEILT
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_ECOL6
Sequence: MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: RTKN_MOUSE
Sequence: MFSRNHRSRITVARGSALEMEFKRGRFRLSFFSESPEDTELQRKLDHEIRMRDGACKLLAACSQREQALEATKSLLVCNSRILSYMGELQRRKEAQVLEKTGRRPSDSVQPAQHSPCRGRVCISDLRIPLMWKDTEYFKNKGDLHRWAVFLLLQIGEQIQDTEMVLVDRTLTDISFQNNVLFAEAEPDFELRLELYGACVEEEGALAGAPKRLATKLSSSLGRSSGKRVRASLDSAGASGNSPVLLPTPAVGGPRFHLLAHTTLTLEEVQDGFRTHDLTLTSHEENPAWLPLYGSVCCRLAAQPLCMIQPTASGALRVQQAGELQNGTLVHGVLKGTNLFCYWRSEDADTGQEPLFTIVINKETRVRAGELEQAPEWPFTLSISNKYGDDEVTNTLQLESREALQNWMEALWQLFFDMSQWRHCCDEVMKIETPAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILAQREGTRLEPSPPWLAMFTDQPALPSSCSPASVAPVPTWMQPLPWGRPRTFSLDAAPADHSLGPSRSVAPLPPQRSPKSRGFYSKSQLGPWLQSPV
What is the function of this protein?
Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis.  May play a novel role in the organization of septin structures (By similarity).
What are the official names of this protein?
Rhotekin.
Protein: ORN_PASMU
Sequence: MQLDKQNLIWIDLEMTGLDPESERIIEIATIVTDKHLNILAEGPVLAIHQSDECLAKMNDWCMKTHTENGLVERVKNSRLTERAAELQTLDFLKKWVPKGVSPICGNSVSQDKRFLFKYMPELADYFHYRHLDVSTLKELASRWKPDVLKGFTKKNTHLALDDIRESIAELAYYREHFINLKNE
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_IPOBA
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HLDD_BURMS
Sequence: MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERFARGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGTQFLYASSAAIYGGSSRFVEAREFEAPLNVYGYSKFLFDQVIRRVMPSAKSQIAGFRYFNVYGPRESHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYGPGEQTRDFVSVEDVAKVNLHFFDHPQKSGIFNLGTGRAQPFNDIATTVVNTLRALEGQPALTLAEQVEQGLVEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVDRYVRWLFGQL
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: RNC_RICTY
Sequence: MESFEKLETLLGYSFKNKELLIEALSHPSLRQYHEYKYDKDYERLEFLGDAVLNLLITEILFKNFENYKEGNLAKIRSYLVCKETICIVGTKLALKDYIIMTHGEEVAGGRDNPNNIENVTEALIAAIYLDSNIEITHNIIEKLWAEFMKVQNLTDYDPKTALQEWAQASSNHLPIYRLIKREGAAHSSIFTVLVKVKDYEQICTGYSIKEAEKKAARCLLHRLKND
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAG_PICTO
Sequence: MNVDPNITKYMIKAKIVTDGVVEKPDVVGAIFGQTEGLLGDELDLRDLQKSGKIGRIEVEIDTKKGRTEGYVLIPSGLDQVESSILAAALETIDRIGPCKAKVEIESIEDVRINKRDRVIKRAEELYRKMGENGKSLSESIVQTVREEVEKKEIISYGEEHLPAGPAIADSDSIIVVEGRNDVLNLLRYGIKNTIAVQGTSVPKTVKELSKSRTVTLFVDGDHGGDLIIKEMLQVADVDFIARAPPGTEVEELTYKQIIKALKYKTPVEQYLETHGMIEELKEWSSRNTKELEERQGNELKNERPEKINENEESEKNVELKEGSVQKLETVPEFDPSSPESIKFKLKQLYESRELELFDGQSSVGKFPVSDAIEKIESMHGDLLITGGIISQRLLDIAYNIGVKAIYGFKIGNITKKPDDIKVVAWDHI
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: YBBY_ECOLI
Sequence: MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATSLAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFGIADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSHSLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTRYRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVPALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMALPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE
What are the official names of this protein?
Putative purine permease YbbY.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPD_METPB
Sequence: MAQNGSEGPLLAGVAGRYALALYELARDEGQVDDVAKNLDAFDALYRESADLRRLVKSPAFSAEEQTAAVGALLDRAGISGLAANFIKLSAANRRLFALPDMIRAYREKVREAKGIVRAEVRVAEKPSDAVIEDIKASLRDVAKSEVDIDLHIDPSLIGGIVVKMGSRMVDASLRTKLNSIRLAMREAR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: T1214_ARCFU
Sequence: MNLGFRVTGKFVRELLDVLDEIAEEIRQEEKEKYPYTEWERKREVVKERLRKLPEYVREAISVITVQKRVGRPKKVDLEKRVMLFLFARLMDKSNRDIEELLELFEPLFGIKVSYKTIERLYSDEEVRMALHNLFILLLREEGVSGDFSGDGTGYSLTITKHYRSNPKRKGKDFRYVFRIIDIDTGMYVGFGYSDRSEKDAFEKALGMLKSMGVKVNSISLDKYYSSRKTLRLFDAETAVYVIPKRNLARIGFDWLRVIERIVEAPYRFLKRYFKRNLSEAGFSADKRRFGWLIRQRREDRREMALFAVGLWHNVFAVRVVR
What is the function of this protein?
Involved in the transposition of the insertion sequence ISA1214.
What are the official names of this protein?
Probable transposase for insertion sequence element ISA1214.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: SYC_HELPH
Sequence: MFIYDTKSKQKVPFEPLVKNKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEVMLVRNFTDIDDKIINKALKENKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAMVHMIETLLEKNIAYRVSNGDIYLDTSKDKDYGSLSVHNSSIEFGRIGLVQEKRLEQDFVLWKSYKGDNDVGFDSPLGKGRPGWHIECSSMVFETLALANTPYQIDIHAGGSDLLFPHHENEACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFVKDALKNYDGEILRNYLLGVHYRSVLNFNEEDLLVSKKRLDKIYRLKQRVLGTLGGINPNFKKEILECMQDDLNVSKALSVLENMLSSTNEKLDQNPKNKALKGEILANLKFVEELLGIGFKDPSAYFQLGVSESEKQEIENKIEERKRAKEQKDFLKADRIREELLNRKIALMDTPQGTIWEKFF
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_PECAS
Sequence: MTYIVALTGGIGSGKSTVADEFAKLGTTIVDADIIARQVVEPGKPALDAIRLRFGDAVLNADGSLNRSALRQRIFSSPEEKQWLNNLLHPLIHQETQAQFRAISTPYILWVVPLLVENGLQQRAQRILVVDVDRKTQLERTLARDGISLQQAENILAVQATREQRLACADDIIDNSRCPNALAQQVAELHRHYLELAASAADRMAKNE
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO_PARMW
Sequence: MQQDGSFSADARFDAVLVGAGIMSATLAALLHELDPGLRLLLVERLEGPARESSAANNNAGTGHAANCELNYTPMQADGTVATAKAVAINAGFERSLEFWGSLRERGELDTSSFLHQAAHISAVWTAENIAFLRQRFEQLSEIPAFAAMRWSEERTELTDWMPLVMAGRDLKQPVAATRIERGTDVDFGALTRAYLEPLQRSGALCVEYGTQVRDIKRLRRGDMTEADWRVILQGPSGKREVRAPFVFLGAGGGALPLLQRSGIPEADDFAGFPVSGLWLVCGDAQLAAKQRAKVYGKAAVGAPPMSVPHLDTRWIDGQRSLLFGPFAGFSSKFLKQGSLFDLPSSVRPTNLLPMLQVGATNIELVQYLINQLRQSPEERHDALQQFMPTARAEDWSLSVAGQRVQIIKRSKQGGRLQLGTEVVASMDGSLAALLGASPGASTAVTIMLEVLQRCFKQRLASAAWNERLQALLPSIGGDPVQDPALLLAMRQRSDALLDLQG
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: NFUA_AZOVD
Sequence: MSAITITDAAHDYLAELLAKQNGTDIGIRIFITQPGTPAAETCLAYCKPHERHPDDIAQALKSFTLWIDAVSEPFLEDAIVDYANDRMGGQLTIKAPNAKVPMIDEDSPLGERINYYLQTEINPGLASHGGQVSLVDIVEEGIAVLRFGGGCQGCGMVDMTLKDGVEKTLLERIPDLKGVRDATDHSNRENAYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: BRC2_HALRO
Sequence: MSAFPISDIGGSWEYSHAPPTATSATGIPGFPEQSVGGLQLPFPGYTYVGASPLTQPRRHFPNSTPVLGNYAGLSSDREVIATSLNPYISKFSANAEWPISDIHQSKKSVYIPEERDVSNQFQTDKQQQQQFMKLPDPQMQVQLCDKELWDQFSRAGTEMIVTKTGRRMFPGYRIKISGLDPTAKYCVMLDIVNVDDHRYKFQHGEWTVAGRGEPHLPQRFFLHPNSPANGSKWMSEIISFHKVKLTNSIGRDVDGKIVLNSMHRYQPRVHIVRTDDISSVHMQRLCTFAFPQTVFITVTAYQNSEVTKLKIDNNPFAKGFREDGARAKKPRNQHNHFSDNDTSPYSEQRRSYYEPGSYTHLPYYNNSPMNVPSHHHYDNQTMNREFLPEAKRNRIMPESNSIHAPSLSVFHPGNENAVSQWQDVPDLNEMYNANDNNYNSVANQSIHNVQYTQNGITSHSPVQPVPHDNSFTYYNSSSPSSSDSNQSNVNASFSVMTTTHASHSINDIMRISEHADVTSPNINIPNTVETNVHSSDSGIGSSPPTPSDDDASNLIPGTEEIFKDDGKVLDGENLPDMSDLISLTERKESGEANANSHTEDFSRNPACQSGDTIESKDIQTLQVASVTDTYSYQKNYVENSSHQSYNNSQEFSYHSNAMPESNCESSVDPNLDWESNLLTM
What is the function of this protein?
Involved in the transcriptional regulation of genes required for muscle differentiation.  Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site (By similarity).
What are the official names of this protein?
T-box-containing protein 2, AS-T2.
What are the subcellular locations of this protein?
Nucleus.
Protein: GNA11_XENLA
Sequence: MTLDSTMACCLSEEVKESKRINAEIEKQLRRDKKDSRRELKLLLLGTGESGKSTFIKQMRIIHGSGYSEEDKKGFTKLVFQNIFTAMQSMIRAMETLKILYKYEQNKANAQVVREVDVEKVCTFEQPYVNAIKNLWSDPGIQECYDRRREYQLSDSTKYYLTDVDRISKPGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKIMYSHLVDYFPEFDGPQRDAATAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  Acts as an activator of phospholipase C.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit alpha-11, G alpha-11, G-protein subunit alpha-11.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cytoplasm.
Protein: PYRB_PSYIN
Sequence: MNNPLYQKNIISISDLSRAELELILTTAQSLKHNPQPELLKNKVIASCFFEASTRTRLSFATAVQRLGGTVIGFDNAGNTSLAQKGETLADSVKIIASYADAFFIRHPQEGAARLAAEFTNIPVINGGDGSNQHPTQTLLDLFTIYETQNRLDNLNIAFVGDLKYGRTVHSLAQALSLFNCNFYFIAPEALAMPDYILEELNEKGINYSVHSSIEEVVDSLDVLYMTRVQKERFDETEYQHIKSAFLLNADMLENVRENLKVLHPLPRVDEININVDKTPYAYYFQQAQNGIYARQALLALLLTNHFQDQA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MTNA_CANAW
Sequence: MSTTTRTLQAIKFDRDNIKLEILDQLLLPYSTSYIPINNIEDAFKAIKLMQVRGAPAIAIVGAFSVVVEVSNYLKQSDSNQKTIKNLNDSLNYLITSRPTAVNLANALNDIKQLLQKYNETDIIDEKIYQQIYDYAITLYDEDLANNKKIGENGLKYIIDTLTEQNFKGPFSIITICNTGSLATSGHGTALGIIRSTYQALQKNNSKQDFWLDHIYPCETRPYNQGAKLTTYELDYEQIPFTLICDNMVSSLINTLSDDNKKPIKTDQSAPVKFIIVGADRIVENGDTANKIGTFQLSTIANFFNTNRFNTTATATNKQIKFIVAAPKTTIDLNTKTGDDIVIEERPANELTTLVGPLLNESGKVGEKLTVGIATPGISVWNPAFDVTPHELIDSIVTEDPHVFTKDKNGEFNLIK
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PB2_I36A0
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRITEMIPERNEQGQTLWSKMNDAGSDRVMVSPLAVTWWNRNGPMTNTVHYPKIYKTYFERVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGIRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGVEPIDNVMGMIGILPDMTPSIEMSMRGVRVSKMGVDEYSSMERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTAQIIKLLPFAAAPPKQSRMQFSSFTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGTLTEDPDEGTAGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: SSRP_LATSS
Sequence: MAKKHPQKPANLIAQNKKAGHDYNILETFEAGLVLTGTEIKSVRKGKISLRDGFARVRRGEAYLENVHISPYEQGNQFNHDPLRNRKLLLHKKEIAKIGALTKDKGITIVPLRVYLKHGFAKVLIGVGEGKREYDKRETLKRKEQDREMARALRKR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: TXC2E_CUPSA
Sequence: AFGTILKALAKIAAKAVKKLATKPGATYMLKQNLE
What are the official names of this protein?
Cupiennin-2e, Cu-2e.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_STRM5
Sequence: MANIKSAKKRAKQTVVRNARNVAQRSMLRTAVKKVIKALDANDAAGAQAAFAVAQPILDRFSARGLIHKNKAARHKSRLNDRIKALAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: CAH4_RAT
Sequence: MQLLLALLALAYVAPSTEDSHWCYEIQAKEPNSHCSGPEQWTGDCKKNQQSPINIVTSKTKLNPSLTPFTFVGYDQKKKWEVKNNQHSVEMSLGEDIYIFGGDLPTQYKAIQLHLHWSEESNKGSEHSIDGKHFAMEMHVVHKKMTTGDKVQDSDSKDKIAVLAFMVEVGNEVNEGFQPLVEALSRLSKPFTNSTVSESCLQDMLPEKKKLSAYFRYQGSLTTPGCDETVIWTVFEEPIKIHKDQFLEFSKKLYYDQEQKLNMKDNVRPLQPLGNRQVFRSHASGRLLSLPLPTLLVPTLTCLVASFLH
What is the function of this protein?
Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH.  May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis.  It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.
What are the official names of this protein?
Carbonic anhydrase 4, Carbonate dehydratase IV, Carbonic anhydrase IV, CA-IV.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: PCBA_PROMM
Sequence: MQTYGKTDVTYAWYAGNSGVTNRSGRFIASHIGHTGLICFGAGANTLFELARYDSALPIGDQGFVVLPHLAGLGIGGIENGVITDSYGMLVVAVFHLIFSAVYAGGAMLHSFRYKEDLGEYPQGSRPNKFDFKWDDPDRLTFILGHHLLFLGLGCVQFVEWAKYHGIYDPAMGVVRKVEYNLDLSMVWNHQIDFLTINSLEDVMGGHAFLAFFLSAGAIWHIFSKPFGEYTEFKGKGLLSAEFVLSTSLAGAAFIAFVAAFWASMNTTIYPTDLYGGPLNIELNFAPYFSDTDPLFGGDLHSARSWLSNFHFYLGFFYLQGHFWHGLRAMGFDFKRVEKLFDQLESNEISLNPAKSTTVPSTSTDSAT
What is the function of this protein?
The antenna complex functions as a light receptor, it captures and delivers excitation energy to photosystems II.  The Prochlorales pcb genes are not related to higher plant LHCs.
What are the official names of this protein?
Divinyl chlorophyll a/b light-harvesting protein PcbA.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. IsiA/Pcb subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: ARGR_SALTI
Sequence: MRSSAKQEELVRAFKALLKEEKFSSQGEIVLALQDQGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPASGFSVRDLYEAILELFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_MANSM
Sequence: MSVSTFNRCWSKVILETLTRHGVKHFCIAPGSRSTPLTLEANRLQEQRRALCHTHFDERGLGFFALGLAKSSQTPVAIIVTSGTAAANLYPAIIEARQTGDNLIVLTADRPDELIECGANQAILQQNMFAGYPVASVNLPRPSQDYIVSWLISTLDQACHQQAQQAGVIHINVPFAEPLYDADEDEIDVHPWLAPVQRWLNHNKPWADHQALQEEVVMHEHWDNWRTKRGVIVAGRLTQEQSMGITAWANTMGWVVLTDIQSGVEPSLPYADIWLANKTVREKLLQADLVIQLGYAFVSKRINQFLADFKGEYWIVDESAHRVDPYHHIHTRFTAKVHHWLRAHPPLRQKPWLLEPLALSKFCASFIEQQVGGNLNEASLAHHIERILPNNGILFLGNSLFVRLVDALGKLPEGYPVITNRGASGIDGLLATAAGVGMGSNQPVVAMIGDVSALYDLNSLALFKNVNQPTIIFLINNNGGAIFDMLPVESSVKSEFYRMPHHTEFSQAASMFDLKYARPYTWADLSSVLKQAYSRKEATVIEIKVGPMDGSNTYKRLIEQISYAVIGA
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: C93C2_GLYEC
Sequence: MLVELAITLLVIALFIHLRPTLSAKSKSLRHLPNPPSPKPRLPFVGHLHLLDKPLLHYSLIDLSKRYGPLYSLYFGSMPTVVASTPELFKLFLQTHEASSFNTRFQTSAIRRLTYDNSVAMVPFGPYWKFIRKLIMNDLLNATTVNKLRPLRSQEIRKVLRVMAQSAESQVPLNVTEELLKWTNSTISRMMLGEAEEIRDIARDVLKIFGEYSLTDFIWPLKKLKVGQYEKRIDDIFNRFDPVIERVIKKRQEIRKKRKERNGEIEEGEQSVVFLDTLLDFAEDETMEIKITKEQIKGLVVDFFSAGTDSTAVATDWALSELINNPRVFQKAREEIDAVVGKDRLVDEADVQNLPYIRSIVKETFRMHPPLPVVKRKCVQECEVDGYVIPEGALILFNVWAVGRDPKYWDRPTEFRPERFLENVGEGDQAVDLRGQHFQLLPFGSGRRMCPGVNLATAGMATLLASVIQCFDLSVVGPQGKILKGNDAKVSMEERAGLTVPRAHNLICVPVARSSAVPKLFSS
What is the function of this protein?
2-hydroxyisoflavanone synthase, which catalyzes the hydroxylation associated with 1,2-aryl migration of flavanones.  Converts liquiritigenin and naringenin into highly unstable precursors of the isoflavones daidzein and genistein.  Acts only on substrates with (2S)-chirality.
What are the official names of this protein?
2-hydroxyisoflavanone synthase, 2HI synthase, CYP Ge-8, Cytochrome P450 93C2, Isoflavonoid synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein.