PharMolix/UniProtQA huggingface dataset:
Protein: PURR_ECO8A
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: SYP_EHRCJ
Sequence: MRLSNYYIPTLKETSADVSVVSHKYSIRAGLIKQIASGIYTWLPLGLRVLRNIENIVREEMNKSGALEVLMPLIQPASLWKESGRYDDYGSEMLRITDRNQREMLFGPTHEEVITDTLRTTLTSHKNLPITLYQIQWKFRDELRPRYGIMRCREFLMKDAYSFDKDLSGAILSYNLMFKTYIKIFKNLGLTPIAVKAESGPIGGNLSHEFHVLANSGESTLYYDQEIIELMNSDNIDIERIKNTYTAADDMHDPQTCPIPPNNIKTSKGIEIGHIFYLGDKYSKPMNANFCDNNDSKPLQMGCYGIGISRLVAAIIEVFHDNKGITWPEEISPFKFSLVNLYSSNDKCIKVAENLHMQLHNDVLYDDTDDSPGIKLTRTDLLGMPWQIIIGKSTVEQDLIEVRNRSNKDKFLISVEQFLKKFKK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_NOVAD
Sequence: MDKIIIRGGKRLSGAVPVSGAKNSALTLLPCALLTDEPVTLRNLPRLADIDGFQHLMNQFGVSTSIAGARPEDFGRVMTLQATRLTSTVAPYDLVRKMRASILVLGPMLARAGEATVSLPGGCAIGNRPIDLHLKALEALGAQIELAAGYVRAIAPDGGLPGGRYSFPVVSVGATENALMAAVLAKGKSTLHNAAREPEIVDLCNLLVAMGAQIEGIGTSDLTIHGVDRLHGATYMVMPDRIEAGSYACAAAITGGEVMLNGARIEDMEATVQALRDAGVHVEPRKGGIYVAADGPLKPVTISTAPYPGFATDMQAQLMAMLCLAHGSSVLTETIFENRYMHVPELNRMGARIETKGRTAVVHGVEKLTGAEVMATDLRASMSLVIAGLAAEGETQVHRLYHLDRGYERLEEKLSLLGAEIERVGGD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_DEHM1
Sequence: MKVAFLKDVPGRGKTGDVKEVNDGYARNYLIPNKLAMPASASVTSEIAAKQAAEDRRKAKAEAEMAQLAKELDGTNVSIKAKTGAKDKLYGQVTTTVIAAEIEKQTGKAIDKRKLELSEPIRQLGSYEVVIRFNKDLSSKINLIITAEENT
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RUVB_CARHZ
Sequence: MEERLVSGYELTEDENEFSLRPRRLSEYIGQQKVKETISIFIEAAKKRNEALDHVLLFGPPGLGKTTLATIIANELGVDIKITSGPALERPGDLAAILTNLGEKDVLFIDEIHRLPRIVEEVLYSAMEDFALDIMLGKGPGARSLRLSLPKFTLIGATTRAGLLTSPLRDRFGMVHRLEFYSVEELMLIINRSAALLKTEITPEGSFEIAKRSRGTPRIANRLLKRVRDYAEVRSSGVINLENAKAALDLLEIDELGLDPTDRLILKTMIEKYQGGPVGIEAIAAAISEEVDTIEDVYEPFLLQIGFIKRTPRGRVVTKLAYDHLGIAYNKNAGELSLW
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YIS1_STRCO
Sequence: MFDTEDVGVFLGLDVGKTAHHGHGLTPAGKKVLDKQLPNSEPRLRAVFDKLAAKFGTVLVIVDQPASIGALPLTVARDAGCKVAYLPGLAMRRIADLYPGEAKTDAKDAAVIADAARTMAHTLRSLELTDEITAELSVLVGFDQDLAAEATRTSNRIRGLLTQFHPSLERVLGPRLDHQAVTWLLERYGSPAALRKAGRRRLVELVRPKAPRMAQRLIDDIFDALDEQTVVVPGTGTLDIVVPSLASSLTAVHEQRRALEAQINALLEAHPLSPVLTSMPGVGVRTAAVLLVTVGDGTSFPTAAHLASYAGLAPTTKSSGTSIHGEHAPRGGNRQLKRAMFLSAFACMNADPASRTYYDRQRARGKTHTQALLRLARQRISVLFAMLRDGTFYESRMPAGVELAA
What are the official names of this protein?
Insertion element IS110 uncharacterized 43.6 kDa protein.
Protein: MRAZ_RHIME
Sequence: MNRFLSHVTNRIDAKGRVSVPSVFRAVLLEAGVRELYCFQDFVFPAISVGGPELLDRFEKQMAAEDPFSDAANEMSLLVHGGGVYVKLDPEGRLMVTDFIRDFTGISNDVTFVGRGDHFQLWDPQAFARAQAEAREGRKQRGLRSQ
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DXS_HELPY
Sequence: MILQNKTFDLNPNDIAGLELVCQTLRNRILEVVSANGGHLSSSLGAVELIVGMHALFDCQKNPFIFDTSHQAYAHKLLTGRFESFSTLRQFKGLSGFTKPSESAYDYFIAGHSSTSVSIGVGVAKAFCLKQALGMPIALLGDGSISAGIFYEALNELGDRKYPMIMILNDNEMSISTPIGALSKALSQLMKGPFYQSFRSKVKKILSTLPESVNYLASRFEESFKLITPGVFFEELGINYIGPINGHDLSAIIETLKLAKELKEPVLIHAQTLKGKGYKIAEGRYEKWHGVGPFDLDTGLSKKSKSAILSPTEAYSNTLLELAKKDEKIVGVTAAMPSGTGLDKLIDAYPLRFFDVAIAEQHALTSSSAMAKEGFKPFVSIYSTFLQRAYDSIVHDACISSLPIKLAIDRAGIVGEDGETHQGLLDVSYLRSIPNMVIFAPRDNETLKNAVRFANEHDSSPCAFRYPRGSFALKEGVFEPSGFVLGQSELLKKEGEILLIGYGNGVGRAHLVQLALKEKNIECALLDLRFLKPLDPNLSAIVAPYQKLYVFSDNYKLGGVASAILEFLSEQNILKPVKSFEIIDEFIMHGNTALVEKSLGLDTESLTDAILKDLGQER
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: SYE2_HELP2
Sequence: MLRFAPSPTGDMHIGNLRAAIFNYIVAKQQHKPFLIRIEDTDKERNIEGKDREILEILKLMGISWDKLVYQSHNIDYHREMAEKLLKENKAFYCYASAEFLEREKEKAKNEKRPFRYLDEWATLEKDKNHAPVVRLKAPNHAVSFNDAIKKEVKFEPDELDSFVLLRQDKSPTYNFACACDDLLYEISLIIRGEDHVSNTPKQILIQQALGLNDPIVYAHLPIILDETSGKKMSKRDEASSVKWLLNQGFLPVAIGNYLITIGNKVPKEVFSLDEAIEWFSLENLSSSPAHFNLKYLKHLNHEHLKLLDDEKLLELTLIKDKNLLGLLRLFIEECGTLLELKEKISLFLEPKDIVKTYENEDFKERCLALFNALKSMDFQAYKDFESFKKEAMRLSQLKGKDFFKPLRILLTGNSHGVELPLIFPYIQSHHQEVLRLKA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS22_NOCFA
Sequence: MAGVVESVPFEGSPRPTIGIEWEVALVDKVTRDLSNTAAAVFDAVGDLRAWDGTPQVTKELLRNTVEIVTGVHETVGAAVEDLRGTMDKVRRAADPLGVDVFCAGTHPFAQWSTQQLTRSPHYDELIERTQWWGRQMMIWGVHVHVGVSHREKVFPILNSLLTTFPHLLALSASSPMWAGSDTGYASNRTLMFQQLPTAGLPFQFENWRQFEHFVHDELKTGVFEQLGGLHWDIRPAPKWGTIEVRICDGIPTHAELAAIAAFIHCLIVDLDQRIEDGEQPITLPPWHVQENKWRAARYGLDAIVITDADSNERLVTDDLMDLLNRLEPTAKRLGCADELAYVATIPERGASYQRQRKVAAASQGDLVAVVDALVHELDR
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-2, Gamma-glutamylcysteine synthetase 2-2, GCS 2-2, Gamma-GCS 2-2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: DHE4_HELPJ
Sequence: MYVEKILQSLQKKYPYQKEFHQAVYEAITSLKPLLDSDKSYEKHAVLERLIEPEREIFFRVCWLDDNHQIQVNRGCRVEFNSAIGPYKGGLRFHPSVNESVIKFLGFEQVLKNSLTTLAMGGAKGGSDFDPKEKSEHEIMRFCQAFMNELYRHIGATTDVPAGDIGVGEREIGYLFGQYKKLVNRFEGVLTGKGLTYGGSLCRKEATGYGCVYFAEEMLQERNSSLEGKVCSVSGSGNVAIYTIEKLLQIGAKPVTASDSNGMIYDKDGIDLELLKEIKEARRGRIKEYALEKTSAKYTPTENYPKGGNAIWHVPCFAAFPSATENELSVLDAKTLLSNGCKCVAEGANMPSSNEAIELFLQAKISYGIGKAANAGGVSVSGLEMAQNASMHPWSFEVVDAKLHHIMKEIYKNVSQTAKEFKDPTNFVLGANIAGFRKVASAMIAQGV
What is the function of this protein?
Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
What are the official names of this protein?
NADP-specific glutamate dehydrogenase, NADP-GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: RL1_STRVG
Sequence: MKRSKTLRAADAKVDREKLYAPLEAVRLAKETSTTKFDGTVEVAFRLGVDPRKADQMVRGTVNLPHGTGKTARVLVFATGDRAAAAEAAGADIVGDDELINEIAKGNRLNEFDAVVATPDLMGKVGRLGRVLGPRGLMPNPKTGTVTMDVAKAVTEIKGGKIEFRVDKHSNLHFIIGKVSFTDEQLVENYGAALDEILRLKPSAAKGRYIKKAALSTTMGPGIHLDSNRTRNLLVEEDPAAV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LCF2_SCHPO
Sequence: MDIKDYYCVETKDSKQPGESYIYRSIHSAGKLLDTPEDGVSTVYDLLCTAAKNHGEKQAMGSRKLIKENREEREIIRKVDNEEVVEKKLWTTYELGPYEYISFNKVYEIALALGSGLVASGITSETTMLFFAATSAKWFTTAQGCSSQAIPIVTAYETLGEDGIYTSLDECKSRAIFTDPNLIPKLLGPLKQSTWVKLIVCSSTPSEDLVELVKSTAPDVEIITYDNLLSLGKEKPQPPHPPKADDICCYMYTSGSTGKPKGVVLLHRNIIAALGGINRILSQHINVKDYVLAYLPLAHIFEFIFEMCCLYWGGVLGYASPRTLTDASVVNCKGDLTEFRPTVLIGVPAVYELIKKGILAKVSSMPAHRQKVFSGSLSLKQYLIERNLPGSAALDAIVFNKVKAATGGRLRYCISGGAALAASTQAFLSSCICPVLPGYGLTETCAGSFVLSPEQWHLYANTVGFPIPSIEFKLVDIPDLGYYTDSSPPRGEVWIRGPAVCNGYLNRPEDNKAAFTEDGWFKTGDVGEIAKGNTLRLIDRKKNIVKSLNGEYIALEKIEAQFFTSPLVSNVCAYADVNHAKPVVIVNPDENGLRTYLTKNSGSSFNGNPNDTLTNLCKDSGVQHLILKELINIGKQQRLASIEIPEGVVLSDFEWTAENNFLTASRKVKRQVIVAHYSDEIQKAYSKKH
What is the function of this protein?
Esterification, concomitant with transport, of endogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids.  Plays an important role in the determination of viability in the stationary phase.
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase 2, Fatty acid activator 2, Long-chain acyl-CoA synthetase 2.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Golgi apparatus. Vacuole membrane; Peripheral membrane protein.
Protein: GAR1_RAT
Sequence: MSFRGGGRGGFNRGGGGGGFNRGGGSNNHFRGGGGGGGGGGNFRGGGRGGFGRGGGRGGFNKFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRPPGEKGPPRGGGGGGGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGFRGGRGGGGGFRGRGH
What is the function of this protein?
Required for ribosome biogenesis and telomere maintenance.  Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs.  May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme (By similarity).
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit 1, Nucleolar protein family A member 1, snoRNP protein GAR1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies).
Protein: GLMU_CROS8
Sequence: MSSHAMSVVILAAGKGTRMYSDLPKVLHTLAGKPMVQHVIDAAKHVGAQHIHLVYGHGGDLLQSTLKDASLNWVLQAEQLGTGHAMQQAAPFFSDDEDVLMLYGDVPLISVDTLQQLCAAKPQGGIGLLTVKLDDPTGYGRITRENGNVSGIVEHKDASDEQRQINEINTGILVANGADLKRWLAKLDNNNAQGEYYITDIIAMAWNEGREIAAVHPQRLSEVEGVNNRLQLARLEHVYQAEQAEKLLLAGVMLRDPARFDLRGTLQHGRDVEIDANVIIEGDVVLGNRVKIGAGCVIKNSVIGDDCEISPYSVVEDALLDTACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKHKTIIGDDVFVGSDTQLVAPVTVAKGATIAAGTTVTRNIAENELVLTRVPQVHKQGWRRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LICB_HAEIN
Sequence: MRGYLFGILSAVFWALSGLLYNELPLSEYTALGKVISLLFLIDFCSLLVIGITLWRKSAVDFQGVFWQPALSGILGGPIGMSAYLLSIHYLTIYYAAPLSSLFPVFAALMSYWILKEKITKTAQFGFALAIISSSLLAIEVGQEITFNTIGFIFLIICILGWSSEIVISSYTMRSLSGLQVYFLRLCGSTIGYLLILFILSLKNFSLDILSFNYVQIAGVIIFGALSYCCYYQAIYLLKPIKAMALNITYSVWAIGLGYLLYKQPIKPITLLLTLLLSAGVIVTLYYKGEQK
What are the official names of this protein?
Protein LicB.
Protein: Y1362_HAEDU
Sequence: MAKKRGKPEIDWTDDDKEIIWVSKSEIKRDSEHLKKLGAELIELTPQNLEKIPLDEDLKYAIRQAQSFKLEARRRQIQFIGKLLRNRDSAPIQDALDKVKNRHNQQQALLHKLELIRDQLINMGDASLNQLLSEYPQLDRQHLRNLIRMAQKEKQINKPAKNYHEILQYLKSELIV
What are the official names of this protein?
UPF0307 protein HD_1362.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: EFPL_ALIFM
Sequence: MPKASDIKKGSAIEHNGKVFFVKEISKLTPSGRAGATLFRMRMYDVATGSKADESFKADDMINLADFSRRSATFSYVDGNEYVFMDSEDYTPYNFNKEAIEEELLFITEETQGLQILIVDGAPVAIELPSAVDLEIVETAPSIKGASASARTKPATMTTGLTVQVPEYIANGEKVKINTTEHKFMSRA
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: RECA_BURL3
Sequence: MTAEKSKALAAALAQIEKQFGKGSIMRMGDGEATENIQVVSTGSLGLDIALGVGGLPRGRVVEIYGPESSGKTTLTLQVIAELQKIGGTAAFIDAEHALDVQYAAKLGVNVPELLISQPDTGEQALEITDALVRSGSIDMIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGSIKKNDEVIGNETRVKVVKNKVSPPFREAIFDILYGEGISRQGEIIDLGVQAKIVDKAGAWYSYNGEKIGQGKDNAREFLRENPEIAREIENRIRESLGVVAMPDGAGQDEAEAMDEEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMG_SHEB9
Sequence: MTTQFSVAGVELELLRYPAQQESNLQAWDAADEHLLKSLIESEQAAVPTAIINDSFGALSCGVSKLNPSWPLCVETDARTSFLGTEQNHGRNQLPLDNLQWFTSRDTLPENLALVLMKLPKNLSYFAHQLTRLSQVLPAGTRVLVAAKAKSINGALLDIFAKHLGPASASLAWKNTRVITCVSDGKPRPLAKEVTWTVPEYQLEISNLSNVFAANKLDIGARIMLENLPKGDFKSIVDLGCGNGVLGLRTAQLFPEADIHFIDDSEMAVASAKANWARNQLPADKGHFYWDDCMTHLPEEVQPDLVLCNPPFHQGEAITDHIAWQMFLDARRRLKDGGILHIVGNRHLAYHVKLQRLFKNCTTVASNGKFVILQAQKK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_STAA8
Sequence: MTKENICIVFGGKSAEHEVSILTAQNVLNAIDKDKYHVDIIYITNDGDWRKQNNITAEIKSTDELHLENGEALEISQLLKESSSGQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGNGVLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEHNILKLVNDKLNYPVFVKPANLGSSVGISKCNNEAELKEGIKEAFQFDRKLVIEQGVNAREIEVAVLGNDYPEATWPGEVVKDVAFYDYKSKYKDGKVQLQIPADLDEDVQLTLRNMALEAFKATDCSGLVRADFFVTEDNQIYINETNAMPGFTAFSMYPKLWENMGLSYPELITKLIELAKERHQDKQKNKYKID
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LERK4_ORYSI
Sequence: MAPPLFLLSLQLLVLLSSPSAQAQNISLGTSLTTQGPNNAWLSPSGDFAFGFRPIDGNSSFYLLAIWFNKISDKTATWYAKTSEQEPQPIQVPSGSILQFTSTGVLSLRDPTNREVWNPGATGAPYASMLDTGNFVIAAAGGSTISWETFKNPTDTILVTQALSPGMKLRSRLLTTDYSNGRFLLNMETQRAALYTMAVPSGNLYDPYWSTPIDENVTNQVTNLVFNTTGRIYVSMKNGTQFNMTSGVIRSMEDYYHRATLDPDGVFRQYVYPKKPSSMSQAWTAVSIQPENICNAQTKVGSGTCGFNSYCMFDGSNNQTSCVCPEQYSFFDEVRKYRGCRPDFELQSCDLDEAASMAQYEFNLVNNVDWPQADYEWYTPIDMDECRRLCLIDCFCAVAVFHENTCWKKKLPLSNGIMGSGVQRTVLIKVPKSNSSQPELRKSRKWKSDKKLWILGSSLLLGGSVIANFALSSVLLFGTYCTITRKDVQPLQPSRDPGLPLKAFSYAELEKATDGFKEVLGTGASGIVYKGQLQDELGTYIAVKKIDKIQHETEKEFAVEVQTIGRTYHKNLVRMLGFCNEGTERLLVYEFMVNGSLNRFLFSGVRPLWSLRVQLALGVARGLLYLHEECSTQIIHCDIKPQNILLDDNFIAKISDFGLAKLLRTNQTQTYTGIRGTRGYVAPEWFKNVGITAKVDVYSFGVILLELICCRQNVEMEAAEEEQSILTYWANDCYRCGRVDLLVDGDDEAKLNIKKVERFVAVALWCLQEEPTMRPSILKVTQMLDGADAIPTPPDSSSVVNSFP
What is the function of this protein?
Does not seem to be involved in resistance against the herbivorous insect brown planthopper (N. lugens, BPH).
What are the official names of this protein?
G-type lectin S-receptor-like serine/threonine-protein kinase LECRK4, OsLecRK4, OsRLCK136.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: HJ01_HUMAN
Sequence: AEYFQHWGQGTLVTVSS
What is the function of this protein?
J region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy joining 1.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: CLPX_PARL1
Sequence: MSKVSGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGVPSPQEICGVLDDYVIGQQHAKRVLSVAVHNHYKRLNHAAKNNDVELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQSADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLEKIIGQRGKGAGIGFGAKVQSVEDRRTGDILKDLEPEDLLKFGLIPEFVGRMPVLATLEDLDEEALLTILTQPKNALVKQYERLFEMENVRLTFSEEALRAVSRKAIERKTGARGLRSILESILLDTMFELPTLEGVEEVVISAEVVEGKARPLYIYAERQGDVGTGA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CAZA2_PANTR
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: CP254_MOUSE
Sequence: MDPILVLVLTLSCLFLLSLWRQSYERGKLPPGPTPLPIIGNILQIDVKDICQSFTNLSRVYGPVYTLYLGRKPTVVLHGYEAVKEALVDHGDVFAGRGRLPVFDKATNGMGIGFSNGSVWKNTRHFSLMTLRNLGMGKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILGCAPCNVICSIIFQDRFDYKDRDFLNLLEKLDEISKILSTPWLQVCNTFPALLDYCPGSHNQFFKNYAYIKNFLLEKIREHKESLDVTIPRDFIDYFLIKGAQEDDNHPLKNNFEHLAITVTDLFIGGTESMSTTLRYALLLLLKYPHVTAKVQEEIEHVIGKHRRPCMQDRSHMPYTNAMIHEVQRFIDLVPNNLPHEVTCDIKFRNYFIPKGTTVITSLSSVLRDSKEFPNPEKFDPGHFLDENGKFKKSDYFMPFSTGKRICAGEGLARMELFLFLTSILQNFNLKPLVHPKDIDITPMLIGLGSVPPAFQLCFIPS
What is the function of this protein?
Metabolizes arachidonic acid mainly to 12-hydroxyeicosatetraenoic acid (HETE).
What are the official names of this protein?
Cytochrome P450 2C54, CYPIIC54.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: SCRY1_ENTDO
Sequence: MPSYTLNYFNHRGRAEICRMLFAAAGVQYNDRRVDCSEWTGMKTQMPCSMMPMLEIDNRHQIPQSMAIARYLAREFGFHGRNNLDMARVDFISDCFYDIMDDYMRMYHDKDGKMMFQRPYDNGNSSERRSRFQETCRRILPFMERTLEMRNGGNQFSMGDQMTMADLMCYCALENPLTDEGSLLSSYPKLQALRGRVMSHMKMSPYLKSRTNTDF
What is the function of this protein?
S-crystallins are structural components of squids and octopi eye lens.  Contains relatively little if any GST activity.
What are the official names of this protein?
S-crystallin 1, OL1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.