PharMolix/UniProtQA huggingface dataset:
Protein: SPAG4_RAT
Sequence: MRRNPRPGSAASSHNHTPNFYSENSNSSHSATSGDSNGRRSAGPELGEPDGRMARGSSCGEPALSSGVPGGDTWAGSSRPKLAPRSHNGQTACGAATVRGGASEPSGSPAVLEEQLNLLPILDLRQEMPPPPVSKSFLSLFFQVLSVFLSLVADGLVCVYREICSIRFLFTAVSLLSIFLAALWWGLLYLIPPLENEPKEMLTLSQYHHRVHSQGQQLQQLQAELSKLHKEVTSVRAAHSERVAKLVFQRLNEDFVRKPDYALSSVGASIDLEKTSSDYEDRNTAYFWNRLSFWNYARPPSVILEPDVFPGNCWAFEGEQGQVVIRLPGHVQLSDITLQHPPPTVAHTGGASSAPRDFAVFGLQADDDETEVFLGKFIFEVQKSEIQTFHLQNDPPSAFPKVKIQILSNWGHPRFTCLYRVRAHGVRISESAEDNAMGVTGGPH
What is the function of this protein?
Involved in spermatogenesis.  Required for sperm head formation but not required to establish and maintain general polarity of the sperm head.  Required for anchoring and organization of the manchette.  Required for targeting of SUN3 and probably SYNE1 through a probable SUN1:SYNE3 LINC complex to the nuclear envelope and involved in accurate posterior sperm head localization of the complex.  May anchor SUN3 the nuclear envelope.  Involved in maintenance of the nuclear envelope integrity (By similarity).  May assist the organization and assembly of outer dense fibers (ODFs), a specific structure of the sperm tail (PubMed:10373309).
What are the official names of this protein?
Sperm-associated antigen 4 protein, Outer dense fiber-associated protein SPAG4, SUN domain-containing protein 4.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum axoneme. Nucleus envelope. Nucleus inner membrane. Note=In spermatids, it is localized in the transient manchette and in the axoneme of elongating spermatids and epididymal sperm.
Protein: GLMU_ECO81
Sequence: MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGNRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENC_YERPG
Sequence: MRTATLYRYSVPMEAGVILRHQRLKSRDGLLVKLQQGELSGWGEIAPLPEFSQETLDQAQVAAECWLQHWVSGVESDDSVLPSVAFGLSCAQAELKQTLPLSADYRKAPLCTGDPDELFAVLQALPGEKVAKVKVGLYEAVRDGMIVNVLLEALPDLTLRLDANRSWSRAKADGFAKYVNPALRSRIAFLEEPCKTRAESREFAQDTGIAIAWDESVREADFQVEAEPGVAAIVIKPTLVGSLARCQQLVQQAHQAGLVAVISSSIESSLGLTQLARLAAWLTPVTVPGLDTLDLMQAQVVRPWPDSPLPLITTEQLGVVWHR
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: VKT31_MESMA
Sequence: MMNVITVVGIILSVVCTISDAEGVDCTLPSDTGRCKAYFIRYFYNQKAGECQKFVYGGCEGNSNNFLTKSDCCKQCSPGKC
What is the function of this protein?
Dual-function toxin that completely inhibits trypsin activity at a molar ratio of 1:1 (dissociation constant of 420 nM) and that inhibits mKv1. 3/KCNA3 potassium channel currents with an IC(50) of 371. 3 nM.
What are the official names of this protein?
Kunitz-type serine protease inhibitor BmKTT-2, Delta-KTx 3.1.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Scorpion delta-Ktx subfamily. Delta-Ktx 3 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: URI_DROME
Sequence: MDRREDALLQALQTNASETERWEAFKRDNESTIRNLDKFAKNLSVEVMVPIGRKALMPGELIHTNELLVGHYEGYFSACSSHKAKEICQYRLKLAEEQLKKLAVENDLWQKKLHTPFAEGAVPSGDQVEIVEDFNEESHNKWLAEHRKRMRQQKQKERLEREAEPVKKDNEVLRKLEEREMMEELGLDPDNIDEDQLHDMLNQEPLKSTNESSPKSLTQEEEDELWKKLEAEEQNEADELSSEAEESLKTTDNLVRQLMSGETETPSSKKRTAGTNRNVEIQDPISEDDGDDDDEGDQEEEVRTIREQMSLLPNEDREPFLRAQLHVLKAKMRKIQKVNFISDELIHLMNVVVMLEDDLQDLVFEQELEASEEEEEVVENNHLPDEPSKELSTVSESSTNKRRISFALDDEKLEFRREETVAEMLPNAKKNSRDIIKLNAPLKPAGDPQPASIKTKRQTTQDILQKVERNIEFVKENQSVQDFDLLNRIMEESTGLINTLHISFTHSGAIPSPSSDQSDGIPGKPSDFYVRYEKDRARPNDSFPIYVNGFEGEEHVKVPIMSEAARGSAYEDPRSQFSKPNSSEICFTHSGSITPTSNDQSDDIPGNPFDFYEKYEKDRAKFSKSNSSEGDATDPESATKSILRNKSAVDLEPHNVNQQPKKGRKVRNQKKKERTLDDDLRDMSAYQKVMHDLVEKEPTAPEPLPPGKFIDSHAPKKRVSRFKEQRALNKT
What is the function of this protein?
Inhibits the activity of serine/threonine-protein phosphatases flw/PP1beta9C and Pp1-87B.  Required for germ line cell viability and differentiation, normal transcriptional activity and maintenance of DNA integrity.
What are the official names of this protein?
Unconventional prefoldin RPB5 interactor-like protein.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase II subunit 5-mediating protein family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome. Nucleus. Note=In primary spermatocytes and maturing spermatids, found throughout the cytoplasm with a distinctive concentration in speckles. In the embryo, primarily cytoplasmic with some protein in speckles in both the nucleus and cytoplasm. In salivary glands, predominantly cytoplasmic with a mild perinuclear accumulation. Also detected on salivary gland polytene chromosomes where it is associated with regions of active transcription.
Protein: VA0D_YEAST
Sequence: MEGVYFNIDNGFIEGVVRGYRNGLLSNNQYINLTQCDTLEDLKLQLSSTDYGNFLSSVSSESLTTSLIQEYASSKLYHEFNYIRDQSSGSTRKFMDYITYGYMIDNVALMITGTIHDRDKGEILQRCHPLGWFDTLPTLSVATDLESLYETVLVDTPLAPYFKNCFDTAEELDDMNIEIIRNKLYKAYLEDFYNFVTEEIPEPAKECMQTLLGFEADRRSINIALNSLQSSDIDPDLKSDLLPNIGKLYPLATFHLAQAQDFEGVRAALANVYEYRGFLETGNLEDHFYQLEMELCRDAFTQQFAISTVWAWMKSKEQEVRNITWIAECIAQNQRERINNYISVY
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:8509410).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:8509410).  This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector (PubMed:8509410).  Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores (PubMed:8509410).
What are the official names of this protein?
V-type proton ATPase subunit d, V-ATPase subunit d, V-ATPase 39 kDa subunit, V-ATPase subunit M39, Vacuolar proton pump subunit d.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: NAT_STRGR
Sequence: MTPRGTAEPQVRPGIAEDLTGLTNLYNHYVLRTPITFDTVPLTPEGRMQWFLSHPKDGPHRLMVAAEPAPSGPERLLGYATSSPLRPKAAYATSAEVSVYCAPDAAGRGVGTALYTALFDALAGEDLHRAYAGVTQPNDASHRLHTRFDFRPIGTYGQVGRKFGRYWDVRWYEKELGGGGADGGAGRLHQTGRM
What are the official names of this protein?
N-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. PAT/BAR subfamily.
Protein: F234B_MOUSE
Sequence: MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSALGDLPEPDSDADVAGAAKPHLSEVTPEGFPSEPLGGLEQKATSPLVSYVRTSVFLLTLVISMVLVLLCAFLIPCPPRDLHSAWSRRLGSQGGGDLSPLELADVNRDGLRDVLLTFVTTRNGTEGGVGSQPTADLVCLSGMNGSTLWSSPLPEEAQDVTCLDLIPGSVAKTICLVTGTRKMLSAFNATSGKVLWTLNPNHLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKHRSVNLSELIDVYSDGVELLQLVKAPDSNSSSLLITTRQGLVLLRGQDLTPHWKLNLQGLRSQPTPGYFTDDQTLDFLLQTQDGDGMKKMTVVDGGSGSIVWSYSIPCHMKETPTTSAITSDQKSVFLFWAEALTAASLSSDDSSGAEPPGLYHLYLLHPAFPSILLDLSNTTGIVTASEVGINDIWKDAFYVTRTTGMSPEGHPTSLVVSKLSLRWALMEGQMVQLKETTPKIGRGELRRFLSRIKFVDSPYQI
What are the official names of this protein?
Protein FAM234B.
What is the protein family that this protein belongs to?
Belongs to the FAM234 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Golgi outpost. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation.
Protein: GLNE_CUTAK
Sequence: MDRKSSVTIDLLRLGVMDTDAASANHHRIAENIGADPNRLADWEHHLETCCDPDLALNVLAELAQDSAQCLGEVLDHDASACRLVRLLGASSELGRHLIAHPDDLAEVIRDPVRLGHDEICDDLLEVVGAHKEGEFTVAGTPTGPASDRLRLANRRHLVRIASRDVSADDPTEIIEDVAAELADLADGIVTAALALARADCPDHADARLAIIAMGKCGAQELNYISDVDVMYVAEPANDDVSGASAVTIATKLAASVARMCSAHSGAGSIWQVDAALRPEGNAGPLVRTMDSMRTYYEKWAKNWEFQALLKARPMAGDLDLGQRFVEMVSPMVWQVGEAEGFVPETRAMRTRVVSLIAAKNKGREIKLGAGGLRDVEFTAQLLQLVHGRQDESLRVRATLPALRALAAGGYISRGAAERLKEAYRLERVMEHRVQMFRLRRTHLLPDDEDGLRRLARAVGLRTADEVRRVWTATSKAVLRAHGQVFYSPVVEAVARIPTQDLRMSAEAAKVRLSALGFHDEDAGLRHIEALTSGTSRAVRIQTALMPAMLAWLADGPSPDHGLLAFRQVSEALGESPWYLRALRDEGAMAQRLAVVLSTSRYAVDVLTRAPETVQVLVDDDLTPLSREDLARQMNAVARRHHDVEEAVGAIRAVRRRKLFRILVADILNVTGIRRIGQALTDLTGATIDAALTAVSREVEDAPPIGIVAMGRWGGQELSYASDADCLFVVGDGPGVGEKALKIVTKLRNLLGKHGADPAVVLDADLRPEGRSGPMVRSLESYRKYYGKWSSTWESQALLRASHGAGDRELTNELLEYVDQVRYPADGLTGSQLAEIRKLKARMESERIPRGVDPRRHLKLGPGGLSDIEWTAQIIQLQHAGHDPALRTTSTIDALNAALAAGYIDEGQHAKLCDSWLAASRLRNAIMVVRGRPSDVIPSDSTDLDVIAKASGMGQGASEHLVEDHLRHCRRASRVVDAVFWNQ
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: AGGDS_STRR6
Sequence: MRKFPLFSSSLSFLLLILFKENDIIVVMEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVTENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVKRYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLRTDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYKTIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRDLDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIWLDFYEKQAALGRK
What is the function of this protein?
Galactosyltransferase involved in the biosynthesis of the bilayer-forming membrane lipid alpha-galactosyl-glucosyldiacylglycerol which is involved in maintaining constant nonbilayer/bilayer conditions (curvature packing stress).  Also involved in the beta-lactam resistance.  Catalyzes the transfer of a galactosyl residue from UDP-Gal to alpha-glucosyl-DAG (1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol) acceptor to form the corresponding galactosyl-glycosyl-DAG product (3-O-alpha-(D-galactopyranosyl-alpha-(1->2)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  It can only use UDP-Gal as sugar donor and alpha-glucosyl-DAG is the preferred sugar acceptor.
What are the official names of this protein?
Alpha-galactosylglucosyldiacylglycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PSBY_PROMS
Sequence: MLRTIVVFAPIIAALAWVIFNIQKPAREQFNRDFLGKD
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: HTPX_STRMK
Sequence: MLTRIALFLATNFAVLILASIVMSLLGVNPSQMSGLLVMAAIFGFGGSFISLLLSKWMAKRSTGAVVITEPRNQTERWLLATVERQAKAAGIGMPEVAVYEGPEINAFATGANRNNALVAVSTGLLHNMSEDEAEAVLGHEIAHVANGDMITMALLQGVLNTFVIVLARVVGGIIDSALSGNREGGGRGFAYYIIVFVLEMVFGLFATMISMWFSRHREFRADAGGASLAGRQKMIAALERLQLNHGQSTLPTQIAAFGIAGSTAKKLFMSHPPLEERIAALRASTVA
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CID2A_SALSA
Sequence: MVLETISRIIKIQLPAYLKKLPLPETIGGFARLTVSEWLRLLPLLGILALLGYLTIRPFLPKKKKQKDSLINLKIQKENPKVVNEIDIEDLKRTNVCYCRCWRSKTFPVCDKSHIKHNELTGDNVGPLILKKKIL
What is the function of this protein?
Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum.  Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy (By similarity).
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 2A.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family. CISD2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein.
Protein: PDXS_HELMI
Sequence: MTTETGTWTVKKGLAEMLKGGVIMDVTTPEQAKIAEEAGACAVMALERVPADIRAAGGVARMADPTVILRIMDAVTIPVMAKARIGHFVEAQVLESLGIDYIDESEVLTPADDLFHINKNDFKVPFVCGARNLGEALRRIGEGAAMIRTKGEPGTGNVVEAVRHARQVMSEIRKLTTLPKEERMSFAKEIGAPYELVCLVAETGRLPVVNFAAGGIATPADAALMMQLGVDGVFVGSGIFKSGDPIRRAKAIVAATTHYNDPKVIAEVSKDLGEPMVGIEIPTIPAEQRMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: MNMA_CHLCH
Sequence: MSTPHHILVGISGGVDSAVATCLLVQQGYRVTAVNLRLLDTLDAPYAEPTLQPSSLVVSDHPDYHIPLFSLNLSRTFRDEVMRYFNAEYLAGRTPNPCMVCNRQVKWAGLRHAAELIGANAIATGHYANRAFSDGRYRLYKGADSQKDQSYFLWMLSQKDLAHTLLPLGGLTKPEVRELAKNFGVRAAEKKESQEICFVPNDDYSTYLMSAMPELAERVADGDIVDAAGTVIGKHRGYPFYTIGQRRGLGVSAKEPLYVTALDAEQNRIHVGHKAALMSHRLLASRCNWIGMEPPSSSVELLGRIRYRDRQTACRVTPLENGQIEVVFQEPKSAITPGQAVVFYCGDEVLGGGFIEEGT
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUER_SHIFL
Sequence: MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMRDQLLALANACPGDDSADCPIIENLSGCCHHRAG
What is the function of this protein?
Regulates the transcription of the copA and cueO genes.  It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator CueR, Copper efflux regulator, Copper export regulator.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_SALNS
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLVRNELSSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSRIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGEDDIVFSDVSDYAANIELAEAIAPQTPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVKDSKSPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVINAGPGSLGPVNMPIPVIIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPVVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNFDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLMDDRKERPGVMFADMELIGIPHTIVIGDRNLDNDDIEYKYRRSGEKSLIKTGDIVDYLVKAIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GENK_CORGL
Sequence: MTSHAPESGGLVTESTLGASNSSQTIENKGLTILGISGRRLAAVLIGWFFVIFDGYDLIVYGTVQSALAKEWNLSSATLGTIGSTAFFGMAIGAVFIGRLSDRVGRKAAVIGSVLILSVFTMLCAFAPNPWVFGAFRFIAGLGLGGLVPSVNAMTSDLVPRKTMSAWATVMMSGVPIGGSIAAVLALVVVPSSEEWGWRFMFLIALIPLVVGLPIAMKVIPSDKAIKADHDIREGHDEPAGFKDLLVDRYRWISIWFALATFVTLLAWYGLGTWLPRLMETAGYEFGHALMFTLALNLGAVIGSVVTAWAGDRFGPIRSGVIAAGIAGIALLLLLTYPPVTAVYVILILAGVGTHGTQILIIAAVANFYPSNLRGTALGWALGVGRIGAVVAPQLAGLLLAWNLGVNSNFIMFGTAALLSALALSVLLRLQKTYSVTHKVEIQG
What is the function of this protein?
Transport of gentisate (2,5-dihydroxybenzoate) into the cell.  Does not transport 3-hydroxybenzoate or benzoate.
What are the official names of this protein?
Gentisate transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRK6_ORYSJ
Sequence: MRRHRPYLDGVAAAAATFLLAVLLHAPLAAGEDEPPPWVLCGPYPPSGNYSKNGTYQVNLDLLSTTLPKNTSSSPAMYATGTVGDVPDKVYGLALCRGDANASACERCVAAALRDAPRRCPLVKDVLVFYDLCQLRYSNRDFFLDDDYFVTTYTLQRSRRVGAAAAAAFDAAVAVLVNATADYAAADSSRRYGTGEEEGVDGDSDRPKIYALAQCTPDKTPEVCRTCLSTVIGQLPKEFSGRTGGGMFGVWCNFRYEVFPFFSGRPLLQLPAFVETPPPPPSPSATSGEKTKNRIGTVLAIVMPAIAAILLMVVACFCCWKRIKKRRPEEQTFLSYSVSSDDIQSIDSLILDLPTIRVATDDFADTKMIGQGGFGMVYKGVLPDGQEIAVKRLCQSSRQGIGELKSELILVAKLYHKNLVRLIGVCLEQQEKILVYEYMPNGSLDIVLFDTDKNRELDWGKRFKIINGIARGLQYLHEDSQLKIVHRDLKASNILLDFDYSPKISDFGLAKIFGGDQSEDVTNRIAGTYGYMAPEYAMRGNYSIKSDVFSFGVLVLEIITGRRNTGSYDSGQDVDLLNLVWEHWTRGNVVELIDPSMGDHPPIEQMLKCIHIGLLCVQKKPASRPTISSVNIMLSSNTVRLPSLSRPAFCIQEVSASDSSNPYSERYPRPRHSGYSDNSTVVSSNDLSITELVPR
What is the function of this protein?
Involved in disease resistance.  Required for NPR1/NH1-mediated immunity to the bacterial blight pathogen Xanthomomas oryzae pv.  oryzae (Xoo).  Required for the benzothiadiazole (BTH)-induced immune response.  Possesses kinase activity in vitro.
What are the official names of this protein?
Cysteine-rich receptor-like protein kinase 6, Cysteine-rich RLK6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TATA_RICAH
Sequence: MGMSFSHLLIVLLIIFVLFGAGKLPQVMSDLAKGLKAFKNGMQDDGSDNDKNK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YCIB_ACTSZ
Sequence: MKQLLEFIPLILFFTVYKLSGIRDAAITLVIATIVQMLILRVKYGKIEKQQVIMGVAVVFFGLLTAYFNEVKYLQWKVTIVYALFAAILLIGQFVFKTPLIRKLLGKEIELPDTAWQKLNLGWAGFFVLCMLVNIYISQYYSEDIWVDFKSFGIIGMTLLATLITGVYIYRYLPKDKD
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHS_SHEWM
Sequence: MTKLADMKCEACQADAPKVTDSELAELIRLIPDWGVEVRDGIMQLERVYKFKNFKLAMEFTNKLAELAEEEFHHPGILTEWGKVTVTWWSHSVKGLHRNDFIMASKTDQLLG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: RSMG_CAMHC
Sequence: MIIKKPENFNEQIEQFGKCLEKFNKIHSITNYNDLSAVIEDSLEGLKFITEMPKVAIDIGSGAGFPAIFLAMVLPYTKWHLFEPNTKKAAFLTYAKVNLKLKNIIIHNTKIENETPFIADLITSRAVMKVPDLIKISHGFFDTHTKFLFYKGSNVKDELGNLKAEIFENNMRKYALLKGNDVC
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_ACIBC
Sequence: MSTPHWFDQGSLVLASNNKGKVAEFEKLFEQLKLPVEIIPQGHLNIPDAIEDGLSFIENAIIKARHASKISGKPAMADDSGICVPVLGGAPGIYSARYAGEHGDDAANNAKLLNDLLPFRKNGEAIEGMFVCVLALVTHAEDPLPQIFQGIWHGEILEAPRGENGFGYDPLFWLPELQVSSAELSKEEKNKISHRGQAMQLFRESLQK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.