PharMolix/UniProtQA huggingface dataset:
Protein: EF1A_COCIM
Sequence: MGKEEKTHINLVVIGHVDSGKSTTTGHLIYKCGGIDNRTIEKFEKEAEELGKKSFKYAWVLDKLKAERERGITIDIALWKFETPKYHVTVIDAPGHRDFIKNMITGTSQADCAILIIAAGTGEFEAGISKDGQTREHALLAFTLGVKQLIVAINKMDSTNWSEPRFNEIVKEVSNFIKKVGYNPKAVPFVPISGFEGDNMIQPSTNAPWYKGWNKETASGKHSGKTLLDAIDAIDPPTRPTEKPLRLPLQDVYKISGIGTVPVGRVETGVIKPGMVVTFAPSNVTTEVKSVEMHHQQLTQGNPGDNVGFNVKNVSVKEVRRGNVAGDSKNDPPKGCDSFNAQVIVLNHPGQVGAGYAPVLDCHTAHIACKFSELLEKIDRRTGKSVENNPKFIKSGDAAIVKMVPSKPMCVEAFTDYPPLGRFAVRDMRQTVAVGVIKSVEKSEKTGGKVTKAAQKAAKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSPB_RAT
Sequence: MAKLHLQWLLLLPTLCSLGAATESASSPDCAQGPKFWCQSLEQAIQCRALGHCLQEVWGHAGANDLCQECEDIVHLLTKMTKEDAFQDTIRKFLEQECDILPLKLLVPRCRQVLDVYLPLVIDYFQGQIKPKAICSHVGLCPLGQTKPEQKPEMLDAIPNPLLNKLVLPALPGAFLARPGPHTQDLSEQQLPIPLPFCWLCRTLIKRVQAVIPKGVLAVAVSQVCHVVPLVVGGICQCLAERYTVLLLDALLGRVVPQLVCGLVLRCSTADAIGPALPALEPLIEKWPLQDTECHFCKSVINQAWNTSEQAMPQAMHQACLRFWLDRQKCEQFVEQHMPQLLALVPRSQDAHTSCQALGVCEAPASPLQCFQTPHL
What is the function of this protein?
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.  SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
What are the official names of this protein?
Pulmonary surfactant-associated protein B, SP-B, Pulmonary surfactant-associated proteolipid SPL(Phe).
What are the subcellular locations of this protein?
Secreted, extracellular space, surface film.
Protein: NQOR_AFIC5
Sequence: MTKVLVLYYSAYGHIEAMANAVAEGAREAGASVDIKRVPELVPAEVAKAAHFKLDQAAPVAKVEDLANYDAIIVGTGTRFGRMSSQMANFLDQAGGLWAKGALHGKVGGAFTSTATQHGGQEMTLFSIITNLLHFGMVVVGLNYGFAGQMGVKEVTGGAPYGATTITDGDGSRLPSENELNGARYQGRTIAETAKKLHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: RL40_HALMA
Sequence: MASFETASDRLLNKQICMRCNARNPQRAQQCRKCGYGNLRPKAKETRSA
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: PO3F4_RAT
Sequence: MATAASNPYSILSSSSLVHADSAGMQQGSPFRNPQKLLQSDYLQGVPSNGHPLGHHWVTSLSDGGPWSSTLATSPLDQQDVKPGREDLQLGAIIHHRSPHVAHHSPHTNHPNAWGASPAPNSSITSSGQPLNVYSQPGFTVSGMLEHGGLTPPPAAASTQSLHPVLREPPDHGELGSHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQPHEVYSHTVKTDASCHDL
What is the function of this protein?
Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.
What are the official names of this protein?
POU domain, class 3, transcription factor 4, Brain-specific homeobox/POU domain protein 4, Brain-4, Brn-4, Octamer-binding protein 9, Oct-9, Octamer-binding transcription factor 9, OTF-9, RHS2 class III POU protein.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: 21DD_HETMG
Sequence: ALAGTIIAGASLTFKILDEV
What is the function of this protein?
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers.
What are the official names of this protein?
Magnificalysin I, HMg I, Cytolysin I, DELTA-stichotoxin.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
Protein: DNAG_THEGJ
Sequence: MKRKKHVLHQILSEKRKAERIRGGNMSAKDEFGTTKYIIYAEFEANGVVERPDVVGAIFGQTEGLLGDDLDLRELQKTGRIGRIRVEVHTKAGKTYGTITVPSSLDRVETAILAAALETIDRVGPAEAHIKVLRIEDVRATKRKYIIERAKEILETLMEEEIPETQELTEEVKKAVRAKELIEYGPEKLPAGPHVPFSDSIIVVEGRADVLNLLKHGIKNAIAVEGTSIPETIIKLSKERIVTAFTDGDRGGELILKELLQVADVDYVARAPEGKEVEELTKKEIVKALRSKIPAEQVITEMFHKGKNFYEILKEKERTAPSKEVKPAPKHEPKPQPVEQKPREEKIIRPIQQAKSPEIEKFEKFIERVKKEQTAILLDENMNVIAEIPVRDLLTTISTRDNIYAIVFNGIITQRLIDIVSENNVRYLVGARKANVVRRPVNLKILTFAE
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: RL20_STRPC
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVADAAAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NUSB_DESOH
Sequence: MASRRRSRELALQFLFSYDLNAAGAGDFDAWMEDFCARFNLSEKNFPHFFTLAQGVKNRWEKLNDLLAESSEHWKLSRMSGVDRNVMRIAIFEMLYCDDVPPRVAINEAIEIGKKYGTDESGAFINGVLDRINKELGGSEADLPENMNTTNSKE
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PFKA_PHOPR
Sequence: MIKKIGVLTSGGDAPGMNAAVRGVVRAALSDGLEVYGIYDGYQGLHQNRIEKLSRTSVSDVINRGGTFLGSARFPEFKDEKVRAQAIQNLKMHGIEALVVIGGDGSYMGAKKLTEMGFPCIGIPGTIDNDVAGTDYTIGYFTALNTVIDAIDRLRDTSSSHQRISIVEVMGRHCGDLTLMSAIAGGCEYIITPETGLHKEELIAKIKEGIYKGKKHAIVALTELMTDANELAKYIEDETGRETRATVLGHIQRGGQPTAFDRILASRMGAYAVELLIQGEGGRCVGVQNEKMVHHDIIDAIENMKRPVRKDLYELADKLF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDST1_HUMAN
Sequence: MPALACLRRLCRHVSPQAVLFLLFIFCLFSVFISAYYLYGWKRGLEPSADAPEPDCGDPPPVAPSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGKFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNTR
What is the function of this protein?
Lacks both N-deacetylase and N-sulfotransferase activities.  Acts as a dominant negative on isoform 1, likely by changing the composition of enzyme complexes responsible for elongation and modification of heparan sulfates.
What are the official names of this protein?
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, Glucosaminyl N-deacetylase/N-sulfotransferase 1, NDST-1, N-heparan sulfate sulfotransferase 1, N-HSST 1, [Heparan sulfate]-glucosamine N-sulfotransferase 1, HSNST 1.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family. NDST subfamily.
Protein: RS16_ECO55
Sequence: MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y5043_PSEE4
Sequence: MLKKTFAALALGTALISAGQAMAAEYKIDKEGQHAFVDWKISHLGYSFIHGTFKDFDGNFTWDSAKPEASKISVDLKTASLWSNHAERDKHIASKDFLDVKKYPEAKFVSTSVKSTGDKTADVTGDLTMHGVTKPVTFKAVFNGEGKDPWGGERAGFNATTTLNLNDFGIKGPGATSQTLDLDISVEGVKQK
What are the official names of this protein?
UPF0312 protein PSEEN5043.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PYRB_STRAW
Sequence: MQRHLISAADLTRDDAVHLLDTAEEMARVADRPIKKLPTLRGRTVVNLFFEDSTRTRISFEAAEKRLSADVINFTAKGSSVSKGESLKDTAQTLEAMGVDAVVIRHGASGAPYRLATSGWIDAVVINAGDGTHQHPTQALLDAFTMRRRLVGRDAGLGRDLAGKRITLVGDILHSRVARSNVDLLHTLGAEVTLVAPPTLLPVGIESWPCEVAYDLDSTLPKSDAVMMLRVQRERMNAAFFPTEREYSRRYGLNGDRMAKMPEHAIVMHPGPMVRGMEITAEVADSDRCTAIEQVTNGVSIRMAVLYLLLGGNEPAVSHTRIEEK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RS21_ACTPJ
Sequence: MPVIKVRENESFDVALRRFKRSCEKAGLLAEVRAREFYEKPTTIRKREKASLAKRHAKRNARENARNTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RS17_STRCO
Sequence: MSESNVTEETKAARGFRKTRQGLVVSDKMDKTVVVAVEDRVTHALYGKVIRRTEKLKAHDEQNAAGVGDRVLLMETRPLSATKRWRVVEVLEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: WNT3A_CHICK
Sequence: MASFGYFLFLCGLSQALSSYPIWWSLAIGHQYSSLGTQPILCGSIPGLVPKQLRFCRNYVEIMPSVAEGVKIGIQECQHQFRGRRWNCTTVNDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSATICGCDTRHKGSPGEGWKWGGCSEDVEFGSMVSREFADARENRPDARSAMNRHNNEAGRTSIIELMHLKCKCHGLSGSCEVKTCWWSQPDFRVIGDYLKDKYDSASEMVVEKHRESRGWVETLRPKYNFFKAPTEKDLVYYENSPNFCEPNPETGSFGTRDRICNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVRCQECIRVYDVHTCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors (Probable).  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:17488271).  Regulates chick apical ectodermal ridge formation (PubMed:17488271).  Required for normal embryonic mesoderm development and formation of caudal somites.  Required for normal morphogenesis of the developing neural tube (By similarity).
What are the official names of this protein?
Protein Wnt-3a.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted, extracellular space, extracellular matrix. Secreted. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: TYPH_SALNS
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNRFREIIQDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITGSILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGQLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPSDFVENYDKYLPTAMLSKAVYADTEGFISAMDTRALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDSIDGQRPLAVIHAKDEASWQEAAKAVKAAIILDDKAPASTPSVYRRITE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: TAAR1_PANTR
Sequence: MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKELHTPTNWLIHSMATVDFLPGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKINILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLINDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
What is the function of this protein?
Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR.  Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin.  Trace amines are biogenic amines present in very low levels in mammalian tissues.  Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.  Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.  The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase (By similarity).
What are the official names of this protein?
Trace amine-associated receptor 1, TaR-1, Trace amine receptor 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PROB_BIFAA
Sequence: MNTPSQAQVRRAIAEAQTIVVKVGSSSLTEPSGHLDPQRLNALVAAIARVRLMGGRVVLVSSGAIAAGFGTLGFDKRPTDVADQQACAAVGQGLLMAQYEAAFARYGLRVGQILITVSDTIAPQQYRNVRRTLDRLLDLGAVPIINENDSLASNEIRFGDNDRLSALIANIVVADALVLLTDVDALYTAPPSEPGSKRISYVPNVEDALAKVQVGGTGSNVGTGGMVTKMEAARVAAVSGIPAVLTCASNAGPAMMGDPVGTAFAPINDRGSSRRLWIGFASHPQGTLVADSGAAKAVRGGAASLLAAGVVEVKGDFAAGDAVWVDDEQGNHLAKGLVGFDSEEIPQMLGRNTAQLKRFLGEEYAHPLVHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARB_CHLTR
Sequence: MSRLPSEDTLLEVNIEDIRVSPFQPRRTFLEEDLKELVLSIKTVGLIHPPVVREIRNGDKVLYYELIAGERRWRALQLAGYKTVPVVLKQVLADDMAAEATLIENIQRVNLNPLEMAEAFRRLIVVFGLTQDKVAKKVGKKRSTVANYLRLFSLPQEVQEKMNSGEISLGHAKVILSLEDENLRQILSQKIISCKLAVREAEMEAKRLVKGKGASLKEDSSSQPSSRLGFCQERLATTFGYPVTVKPQGRRICVSFFVEGEEALEALEKALTTSSSEAILT
What is the function of this protein?
Involved in chromosome partition.  Localize to both poles of the predivisional cell following completion of DNA replication.  Binds to the DNA origin of replication (By similarity).
What are the official names of this protein?
Probable chromosome-partitioning protein ParB.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
Protein: LIN54_XENTR
Sequence: MDVVSTDVNNVLPDEIMETGISLVDDDSIEAITISSPMVDEAPMETELERIVEVSSSGECVSTAVVKEAVASTSNNAGHLAVVSVASKPESGPSAAAMKTVLQTHFHKLATPISGQVVLNKVSQASDLTAGSHVVKQEGQKLIVTTLGKSSHPIVLTLPQSHIGNAQTPVTHVQRIESKVTPQQIKLVTIGGNRSDGNPVLGMSALTSAQIISPSTKSPVLQTQQIKTLQIAKKAPTSSGPVITKLIIAKPLNSKPLTEQTTQIASSFAGGPALSQTNPGTPPKALNIADIGVIGTPSAKTTNKIAISPLKSPSKGVKSSVGGINTPQFKTIIPLAAAPNVQQIQVPGSKFHYVRLVTASTASNTTPSSQIQSTSTQPLQQAKPVVVNATPVRMSVPIIPAQTVKQVVPKPLNAASQIVTTSQPQQRLLMPATPLAQIQPSLTNLPAGTVLASAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNAGLSGTTAAQNQPRGPLNGIISSESASRPRKPCNCTKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGKEGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADAAEVRVQQQTAAKTKLSSQISDLLTRPAPPMNSGGGKLPFTFVTKEVAEATCECLLAQAEQAEKQLKSKAATERMILEEFGRCLMRVINSAGKAKTDPCPMSC
What is the function of this protein?
Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context.  Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA.
What are the official names of this protein?
Protein lin-54 homolog.
What is the protein family that this protein belongs to?
Belongs to the lin-54 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAIT_ECO45
Sequence: MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
What is the function of this protein?
Catalyzes the exchange of L-carnitine for gamma-butyrobetaine.
What are the official names of this protein?
L-carnitine/gamma-butyrobetaine antiporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LGT_STRZT
Sequence: MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPDDILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLYIFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMYIEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMRTDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLYL_BOVIN
Sequence: SALYALYDFSPPARKMRAYTVRAYVHGSYSRRGPWYDFEPVPGASMDGL
What is the function of this protein?
Manifests poly C-specific RNase activity toward yeast tRNA, elicits a dose-dependent inhibition of cell-free translation, inhibits formation of superoxide ions in vitro and inhibits the hemagglutinating activities of soybean lectin and Ricinus communis agglutinin 120.  Inhibits HIV-1 reverse transcriptase.
What are the official names of this protein?
Glycolactin.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEC_CHRVO
Sequence: MNQASDEKALVVLSGGQDSTTCLYWALRRFGAGKVEAVTFDYGQRHRVELDCARKIAALAGVRQTVLPIDTFAAIGGNALTDASIAPEEGVRDDDALPNTFVPGRNLVFLTFAAAFAYTRGARHLVTGVAQTDYSGYPDCRENTLKALEVALRLGMDSRVELHTPLMYLSKAETVTLAQQVGALEALAWSHTCYNGEVPPCGHCASCELRAKGFAEAGVPDPLVERCQAEAQGL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ISDE_STAAR
Sequence: MRIIKYLTILVISVVILTSCQSSSSQESTKSGEFRIVPTTVALTMTLDKLDLPIVGKPTSYKTLPNRYKDVPEIGQPMEPNVEAVKKLKPTHVLSVSTIKDEMQPFYKQLNMKGYFYDFDSLKGMQKSITQLGDQFNRKAQAKELNDHLNSVKQKIENKAAKQKKHPKVLILMGVPGSYLVATDKSYIGDLVKIAGGENVIKVKDRQYISSNTENLLNINPDIILRLPHGMSEEVKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPFGITANVDADKAMTQLYDLFYKDKK
What is the function of this protein?
Involved in heme (porphyrin) scavenging.  Binds Fe(2+) and Fe(3+) heme but the largest fraction is Fe(2+) heme.  Functions as a high-affinity heme binding protein and probably has a role in relaying heme-iron from cell wall-anchored isd proteins receptors to the probable permease IsdF (By similarity).
What are the official names of this protein?
High-affinity heme uptake system protein IsdE, Iron-regulated surface determinant protein E, Staphylococcal iron-regulated protein F.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 8 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ZN639_BOVIN
Sequence: MNEYPKKRKRKTLHPSRYSDSSGISRIADGFNGIFSDHCYSVCSMRQPDLKYFDNKDDDSDTETSNELPKFTDGIKARNRNQNYLVPSPVLRILDHTAFPTEKSADIEICDEDCDSPESVHQQTQEESPIEVHTAEDVPIAAEVHAISEDYDIETENNSSESLQDQTDEEPPAKLCKIVDKSQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACKLIELSDKYNNGEHGQYSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIEDLKIHLDFKHSADLPHKCSDCLMRFGNERELISHLPVHETT
What is the function of this protein?
Binds DNA and may function as a transcriptional repressor.
What are the official names of this protein?
Zinc finger protein 639.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPPH_ACIAC
Sequence: MLDRDGFRPNVGIILLNQRNQVFWGKRIRTHSWQFPQGGIDRGETPEQAMFRELHEEVGLQPCHVRVVARTRDWLRYEVPDRYIRRDARGHYKGQKQIWFLLQLVGHDWDLNLRATNHPEFDAWRWNDYWVPLDVVVEFKRGVYEMALTELARFLPRNDQRNRYLRSGMRQREGAPEVSLGTTTQLRTTSLLVHPGMELPPGASFDPDPRTGDGDPGMPGIHKPAG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: NUCS_MYCTU
Sequence: MSRVRLVIAQCTVDYIGRLTAHLPSARRLLLFKADGSVSVHADDRAYKPLNWMSPPCWLTEESGGQAPVWVVENKAGEQLRITIEGIEHDSSHELGVDPGLVKDGVEAHLQALLAEHIQLLGEGYTLVRREYMTAIGPVDLLCSDERGGSVAVEIKRRGEIDGVEQLTRYLELLNRDSVLAPVKGVFAAQQIKPQARILATDRGIRCLTLDYDTMRGMDSGEYRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.