PharMolix/UniProtQA huggingface dataset:
Protein: F124A_HUMAN
Sequence: MDPKAGGGGEEDDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDNVLAWIHPDLPLFRVSERRASRRRRKPPKGAQPALAVVLFLQEEYGEEQILQLHRTLQQPPWRHHHTEQVHGRFLPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTVYCRYDNYADSLRFYQLILRRSPSQKKADFCIFPIFSNLDVDIQFSLKRLPCDQCPVPTDSSVLEFRVRDIGELVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRVHKKFPKPGRVHHASEKKRHSTPLPSTAVPSHTPGSSQQSPLNSPHPGPIRTGLPPGHQQEFAGRANSTPNPPWSFQRSKSLFCLPTGGPSLASSAEPQWFSNTGAPGHRASEWRHGHLLSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCSTVETPLPSERCSSHWAAHKDSREGPLPTVSRVTTEASWASLPFFTKRSSSSSATARAAPPAPSTSTLTDSSPQLPCDTPKVKQTDGDMPPPPGSAGPGDNDMEEFYI
What are the official names of this protein?
Protein FAM124A.
What is the protein family that this protein belongs to?
Belongs to the FAM124 family.
Protein: Y1205_PSEAE
Sequence: MSNTEERCDLSSSRDCPERHEHLLQRVTARAAEIGGGITVSRLMPSRQRRMIGAWCFLDHAGPAEFEPGGGLAVGPHPHIGLQTFTWMIQGEALHRDSLGNVQVIRPGQVNLMTAGHGIAHTEESLPDERHAHAAQLWIALPYEQRDIAPAFDHHPDLPRWQEQGVTFTLLAGALAGRQAPCRLYSPLLGADLACHDASTLQLTLDPHFEYGLLPLEGGLEVGGEHFAVNELAYLGDGRDGLQLQLDPGARVLLLGGAPFGAEIFMWWNFVGHSKGEIARAQKAWEEGDARFGRLDALEGPRLSAPPIPWKIDAE
What is the function of this protein?
Putative quercetin 2,3-dioxygenase.
What are the official names of this protein?
Putative quercetin 2,3-dioxygenase PA1205, Putative quercetinase, Pirin-like protein PA1205.
What is the protein family that this protein belongs to?
Belongs to the pirin family.
Protein: THIM_CHLAA
Sequence: MTLNERIAELRERVRQQRPLIHHITNFVVMNDTANVTLHIGGLPVMAHDRAEVAEMVTAAGALVLNVGTLSPDWIEAMLIAGRRANELGIPIVLDPVGAGATSLRTASNRRLLEELQIAVVRGNSGEIGALAGMGGVVKGVETVVEVDDPTAAAKALAQQYRTVVAVTGRQDVVTDGKRVFLVDNGHEWLKTLTGTGCSATTVIAAFAAVEREYPFAAAAALACFGLAAELAAPAARGPASFKVAFYDAIYHLSADQIRAGARVTAVAG
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: NUOK_FRATF
Sequence: MRALKMNSISVSVTHGLIFSILLFVISVAGIIINRRNILILLMSIELMLLAVNTNFLIFANMHQQAMGGVFVFFIMAVAAAETAIGLAIVVAIFRKRKTIDLSKLNTLRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPF_COXB1
Sequence: MKVNFTKMQGSGNDFVVIDATKTPFQLTTSQIQKMANRRFGVGFDQLLVIEPPKNNSVDFHFRIFNADGSEVGQCGNGARCIARFIRAHQLSDREELRVSTLNEVLELKIQPDGKVSVKMGVPRFEPTEIPFIASGVANFYDIAVDNQIVKLGVVNIGNPHAIIPVERINAEEVGKLGARLSVHECFPEGANVGFMQVIDPQNIRLRVYERGTGETLACGSNACAAVAVGRRCGLLQERVVVSQPGGSLTIDWQGPLTPVTMTGPATTVFCGEWLD
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPA_SALNS
Sequence: MPFTLGQRWISDTESELGLGTVVAMDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHEGWQLHIDEVKEENGLLVYVGTRLDTEETNVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPYSGLRGQRTNLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYTEAQHDAYNPFETEQLVICSLDFARRNKQRLEHLCDAEWDLLVVDEAHHLVWSTDAPSREYMAIEQLAERVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQKNYRPVADAVAMLLAGNKLSNDELNRLGDLIGEQDIEPLLQAANSDRDDAQAARDELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTVKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKATTALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRAIYDSAYASLINYLAAPEETDGFDDLIKSCREQHEALKAQLEQGRDRLLEIHSNGGEKAQQLAQSIEEQDDDTNLIAFAMNLFDIVGINQDDRGDNLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELVYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLSAVNRHTGSKLVNAVQQDVYAILQLGETQIEQSARALIDNARREADEKLSGELSRLEALRAVNPNIRDDELAAIDSNRQQVLESLNQAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: MOAC_STACT
Sequence: MSEFTHINEQGNAKMIDVSEKEITKRTATAHSSITVNQDIYQQIVDHTNKKGNVLNTAQIAGIMAAKNTSTIIPMCHPLSLTGIDIAFEWDTTSSYTLNIEATVSTSGKTGVEMEALTAASATALTVYDMTKALDKGMVIGETYLLTKSGGKSGDYRRESK
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: EFG2_TRIEI
Sequence: MAKDLTNYRNFGIFAHVDAGKTTTTERILKLTGKIHKIGEVHEGAATTDFMEQEQERGITIQSAATSCFWKDHQLNIIDTPGHVDFTIEVYRSLKVLDGGVGVFCGSGGVEPQSETNWRYANDSKVARIIYVNKLDRTGADFYKVVKQVKDVLAAEPLVMVLPIGIENDFVGVVDLLTRKAWVWDDSGDPTKYEIKDVPENMTDDVEKYREMLVETAIEQDDEVMEKYLEGEEPDLDTLKRCIRKGTKDLVFFPTYCGSSFKNKGVQLVLDAVVDFLPNPTEIKPQPEIDLEGNETGKFAYVDPEKPLRALAFKIMDDKYGALTFTRIYSGTLSKGDTVLNTFTGKTERIGRLVEMHADSREEIESAQAGDIVAIVGMKNVQTGHTLCDPKEPATLEPMVFPDPVISIAVAAKDKGSVEKLGMALSKMVQEDPSFRVETDAESNETIIKGMGELHLDIKVDILKRTYGVDVEVGKPQVAYRESITKRLEDSYTHKKQSGGSGQFAKIDYMIEPGEVGTGFDFQSKVTGGNVPREFWPAVQKGFETSFEKGMLAGYPCVDMKFTLMDGAFHPVDSSAIAFEIAAKAAYRQSFSKAAPQLLEPIMKVDVFTPDDHVGDVIGDLNRRRGMIKSQDSAATGSRIKADVPLSEMFGYIGDLRTMTSGRGQFSMEFSHYAPCPANVAEVVIKEAKERQEAKSK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT5F_CONTE
Sequence: CCPPVIWCC
What are the official names of this protein?
Conotoxin tx5f, Conotoxin Tx5.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUX5_ARATH
Sequence: MATETNENLINSFIEITSSSREEANFFLESHTWNLDAAVSTFLDNDAAAAAEPNPTGPPPPSSTIAGAQSPSQSHSPDYTPSETSPSPSRSRSASPSSRAAPYGLRSRGGAGENKETENPSGIRSSRSRQHAGNIRTFADLNRSPADGEGSDSDEANEYYTGGQKSGMMVQDPKKVKDVDELFDQARQSAVDRPVEPSRSASTSFTGAARLLSGEAVSSSPQQQQQEQPQRIMHTITFWLNGFTVNDGPLRGFSDPENAAFMNSISRSECPSELEPADKKIPVHVDLVRRGENFTEPPKPKNPFQGVGRTLGASGSGSSSAPQASSAPMNVAPAPSRGLVVDPAAPTTSIQLRLADGTRLVSRFNNHHTVRDVRGFIDASRPGGSKEYQLLTMGFPPKQLTELDQTIEQAGIANAVVIQKF
What are the official names of this protein?
Plant UBX domain-containing protein 5, PUX5.
Protein: Y703_ENT38
Sequence: MYDNLKSLGITNPDEIDRYSLRQEANNDILKIYFHKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYVIDELDQICQRDRTEVDLKRKILDDLRHLESVVTHKISEIEADLEKLTRNK
What are the official names of this protein?
UPF0325 protein Ent638_0703.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: SC5A6_MOUSE
Sequence: MSVASTAAPFHTTSGSSGAISTFSVVDYVVFGLLLVLSLVIGLYHACRGWGHHTVGELLMADRKMGCLPVALSLLATFQSAVAILGAPAEIFRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKAVRICGTVTFIFQMVIYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGLKAVIWTDVFQTLVMFLGQLVVIIVGAARVGGLGHVWNVTSQHGLISGINLDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSHSERAAVLSCYAVFPCQQVALCMSCLIGLVMFAYYNMYSMSPELKQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTMEDLIQPWFPQLTETRAIMLSRGLAFAYGLVCLGMAYISSHLGSVLQAALSIFGMVGGPLLGLFCLGLFFPCANPLGAIVGLLTGLTMAFWIGIGSIVSRMSSAVAPPPLNGSSSFLPANVTVAAVTTVMPSTLSKPTGLQHFYSLSYLWYSAHNSTTVIVVGLIVSLLTGGMRGRSLNPGTIYPVLPKLLALLPLSCQKRLCWRSHSQDIPVIPNLFPEKMRNGVLQDSTDKERMAEDGLVHQPCSPTYVVQETSL
What is the function of this protein?
Sodium-dependent multivitamin transporter that transports pantothenate, biotin and lipoate (By similarity).  Required for biotin and pantothenate uptake in the instestine (PubMed:23104561).  Plays a role in the maintenance of intestinal mucosa integrity, by providing the gut mucosa with biotin (PubMed:27492331).  May play a role in the transport of biotin and pantothenate into the brain across the blood-brain barrier (By similarity).  May also be involved in the sodium-dependent transport of iodide ions (By similarity).
What are the official names of this protein?
Sodium-dependent multivitamin transporter, Na(+)-dependent multivitamin transporter, Solute carrier family 5 member 6.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1664_METJA
Sequence: MNKLKLKNEKEVRIKFGEYKLTGFSSDNGNNLYKLFNLTLSKIRYRKAMLEHNFQLPKIKESHKPKEITEKIKENDIYFLELINEIKKDFKDFCSLDAGTLFELFMYYTLIEFFKENNIDAKVIRNLDVSYKGNIFTEIDLFVDVFGKNFIFECKNRHISSNAILKLYGIMKILNINFGVLASTKGFYGNLKKEDIFKEYNIYILDKLIEKEKNKIFKELKDIFNI
What are the official names of this protein?
Uncharacterized protein MJ1664.
Protein: NAPA_ECO27
Sequence: MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLLRMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAASKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYIIQNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVAEYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPSGTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVSDPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFSRRFKTEEVWPEELLAKKPELRGKTLYEVLYATPEVSKFPLSELAEDQLNDESHELGFYLQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGEGYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRAFPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAAQLVNKLTLDATDPLSKETDFKKCAVKLEKV
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PROB_BURP1
Sequence: MRSIIADSKRLVVKVGSSLVTNDGRGLDHDAIGRWAAQIAALRGAGKEVVLVSSGAIAEGMQRLGWSKRPREIDELQAAAAVGQMGLAQVYESRFAEHGIRTAQILLTHADLADRERYLNARSTLLTLLRLGVVPIINENDTVVTDEIKFGDNDTLGALVANLIEGDTLVILTDQPGLFTADPRKDPGATLVAEASAGAPELEAMAGGAGSSIGRGGMLTKILAAKRAAHSGANTVIASGRERDVLVRLAAGEAIGTQLIARTARMAARKQWMADHLQVRGHVVIDAGAVDKLTAGGKSLLPIGVVAVQGVFARGEVIACVDDTGREVARGITNYSSAETKLIQRKPSGEIETVLGYMLEPELIHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_CHLFF
Sequence: MKLARTVSVAVTGGTGQIAYSFLFALAHGDVFGSDCGIDLRVYDLPGLERVLSGIRMELDDCAYPLLQSLRVTTSLEDAFDGIDAAFLIGAAPRGPGMERSDLLKRNGEIFSLQGSVLNTSAKRDAKIFVVGNPVNTNCWIAMSRAPKLNRRNFHSMLRLDQNRMQAMLAHRAQVPLDEVTNVVIWGNHSAKQVPDFTQSLISGKPAVEVISDRDWLENIMLPSIQNRGSAVIEARGKSSAGSAARALAEAARSIFVPKEGEWFSTGVCSDYNPYGIPEDLIFGFPCRMLPSGDYEIIPGLSWDVFIKNKIQISLDEISQEKANVSLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: TOF1_EMENI
Sequence: MEEAVPAQTVEVIDPEVRAHVYSLLGGFNGEDADKYVLGDDALSCLRDIKRWLKLYDEKFNRMDVARCLGEANLVNGDLIQILSLWWREGQQSKYMTRIALACVELLVPLTWPLEIHGEMTVNHHRHIPYLQQAQVGYKRGILNMASCGILRAVIRIGLPSMAIPPSERTARDEGILKIMLYLLRNIAIITANARLAAEGEEEETSRSATINAFHDQDVFALLLTLCSNVSDDFNMLDIPLLEILFHMVRGIDVEKLFMNDAQRSAKRTDELNDLLRQESSMRREYAKNAPTRHGRFGTMIWVKRDDAKMSTVSGQDVLRDEQTTLYKMDQSKRWNKPRRGRKAQDMSVNNDFNTPVHISPSATTNLRMFVEEFLDSGFNPLFVHVRKAIERESIRVLDINKRHFLYTVSWFLGAERARRARQREKYAQSGKKPDNELEPDSFGLVAGVLNQETFVFLNRSMQNSLDNKEWDDLNAAMRCFTQILLTVQEMSQSPLEEDQEIAENIQNRIFYEETTHDRILAILRGYTDQGFGYLDACTELSHVFLRMLERYSKTNVDMQVRSRRRARKRKREEQLVNKGSDEEQESEDEDYAEAEKMSKERKFDFTRFAAKFSNQKCVDTFVAFTKFYKELNNEQLKRAHRYFYRIAFKQEMTVLLFRVDILNLFYRIIKGPGGMDSSKPIYKEWEELVRQLIRRLIKKLEQRPALITELLFSKINSTAFYLEYGFEKQTVTTSKRAPAELEVDPKAASTPEEKLSIVVAALVKDEQSALVKWISEVLGSAADEREAWELNSHDVDLAGPRDTQNPIITVKSQDNSFKRAMFQNAKLRLLMTLLKFDRLGQENVEGISWIIPSELKSDELRESKAVIDKALLIGNTDERDPNDLLRKKYSHEPRDGFSGQNLDVNFGSDSEGEDVIPDGPLFPANPRSKAHALNELKQKRKKRKDKGEEEPVDEETLEERRQARLENTRWRLAKIKSDLYVHASDEESDAEADQEFFRLEEERRNEQSERIKKALLLGRTEDAGNKARQRKRGKRSNEPNIAGEEETSGKRRRHSGGTNVELEEDDILMDDMEMPSRASSGEYSSNDADAIDKSMAAAEDELYFDDDLAFGRDRDKDETSVDRDGADASSPRKHNDGSESAEEDIPLAPPNRRRLRAGFVVESDSE
What is the function of this protein?
Involved in chromosome segregation during meiosis and DNA damage repair.
What are the official names of this protein?
Topoisomerase 1-associated factor 1.
What is the protein family that this protein belongs to?
Belongs to the timeless family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCAF8_HUMAN
Sequence: MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS
What is the function of this protein?
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
What are the official names of this protein?
DDB1- and CUL4-associated factor 8, WD repeat-containing protein 42A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF8 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=It shuttles between the nucleus and the cytoplasm. Nuclear import is mediated by KPNA1 and KPNB1 under the regulation of nuclear GTPase RAN. Nuclear export to the cytoplasm is XPO1 dependent.
Protein: S2A4R_HUMAN
Sequence: MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRIGVTLRKPRGDAKKCRKVYGMERRDLWCTACRWKKACQRFLD
What is the function of this protein?
Transcription factor involved in SLC2A4 and HD gene transactivation.  Binds to the consensus sequence 5'-GCCGGCG-3'.
What are the official names of this protein?
SLC2A4 regulator, GLUT4 enhancer factor, GEF, Huntington disease gene regulatory region-binding protein 1, HDBP-1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus.
Protein: RL15_PELUB
Sequence: MTTLNTTGKVLYKKKMRVGRGIGSGKGKTSGRGVKGQKSRSGVAIKAFEGGQMPLYRRLPKRGFNAIKRYQAVIAIMNLEKIQTFITEKTINSGDVINMALLKKLKLINKNSQKLKILGTGEIKDKVNIEADLISKSAVEKLEKAGGTIQLKK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SYR_PYRAE
Sequence: MDPLRQPREEFVKVLGEVSRELGLPEVPEVERTRRYGFFSARFHKYKVDHSRLAEVVNLIKNKRFEFLSSLSVDGLYLNADLNVSKVAELVFEAVVKMGRKYGFTEECVTGSYLVEHTSANPVHPLHIGHGRNAILGDSLARLLKFCGNKVETHFYVDDCGVQVMYAAMGYNAVKDEVKKRIEKSKPDVVIGHVYSATNAVAEIGRLKKELEKAQDDERKREILREIDEWVAVLKRLMDSEGDIISKIAEELGRRDLLNEAVELNRRYESGDPEAKGVVREVVDLVLKGQRETLARLGVEIDKWDYESELTVWSSEAMRIVSELQKRWPQYIEIKGGAVVFRADKFVQDYNLWDVLDLPRFIPPVTLTRSDGTTLYVTRDVAYALWQARQGFDKVIRVISTEQTHEQAHVRIILYALGYVDEAKKIVHYAYEMVNLPGMKMSARRGQYISLDEILDEAAERSASLVKEKNPEVSGVIAERVGVGSVRYAFLTTSPRKPIEFKWDVVLNLRQNSGTFLQYTYVRAYSILEKAGEIGNVPVPENMLAEERELVLKIAEWPSVVKEAAKSLRPDYVAEYLDGLALVFNSYYEKAPVLKAEESVRGFRIAIVNAVKTVLEAGFYILGIPTLTKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_ECO24
Sequence: MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERARAASIPDATERVANEVSRAARA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RF2_CORGL
Sequence: MRPEFSAELSELDSTLTTIEKVLNPQEMSDRVRELEAQAADPSLWDDPDHAQQVTSELSHVQAELRKITDLRQRIEDLPIMVELAEEEDGDTSIAEEELADLRSLIDALEVKTMLSGEYDAREAVINIRSGAGGVDAADWAEMLMRMYTRWAEKNGHKVDIYDISYAEEAGIKSATFVVHGDYMYGQLSVEQGAHRLVRISPFDNQGRRQTSFAEVEVLPVVEKVDSIDIPDADVRVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQIQNKASAMRVLQAKLLERKRQEERAEMDALGAGGNASWGNQMRSYVLHPYQMVKDLRTNFEVNDPQKVLDGDIDGLLEAGIRWRMAESQSAE
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU80_COCIM
Sequence: MAEKEATVYIVDVGHSMGKCRGGRTISDLDWMMLYVWDRITTTVSTGRKTATVGVVGLRTDGSSNPLWEKDEEESYAHLSVFQEIGQMLMPDIRKLRDLVKPSNTNQGDAISSIILAIDMIVRYCKRLKYKRKIVLVTDGRSTMDSDGIDSIVSKIKEEGIELVILGVDFDDPDYGFKEEDKDPFKTKNESVLKILADDADGAYGTLAQAVEEMTTPRIKVVRGIPSFRGDLRLGDPSQYSTGLTIQVERYYRTYVARPPAASAFALSIAPPKGQSTAESSVTLQNGDSTVETANASNNLSGVRNARSYQVIDENAPGGKKEVERDDLAKGYEYGRTAVHISESDEVITKLDTTAALEFIGFIQSENYERYMNMSTSNVIIAQKINDKAILALSSMIHALFELEYYAIGRLVTKDGKPPLMVLLAPLIETDFECLLEVQLPFAEDTRSYRFPPLDKIVTVSGKVVKEHRNLPSDDLLETMGKYVEDMDLSEFDENGDPFQSLALEDCYSPLVHRIDQAIRWRAVHPTKPLPPVPKVLEKLSHWPEELVKKSHDSLRDLISISAVKKVPPKAKGRKRRREADKPLSGLNVDDLLRGEKRLKISPENPIPEFKQTLANTEDISAISDAVKQMSAIIEDQIRQSLGDINYDRAIEGIGTMREELIAYEEPGLYNDFIRGLKEKLLDDKLGGDRREMWWLIRKSRLGLIDQKALDISDITEEQAREFLSSRPTTV
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair.  DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA.  Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection.  Required also for telomere recombination to repair telomeric ends in the absence of telomerase.  KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase.  Involved in telomere maintenance.  Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement.  Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere.  Required for mating-type switching (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase II subunit 2, ATP-dependent DNA helicase II subunit Ku80.
What is the protein family that this protein belongs to?
Belongs to the ku80 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: MSRB3_HUMAN
Sequence: MSPRRTLPRPLSLCLSLCLCLCLAAALGSAQSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVINSEAITFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVASPAQADKAEL
What is the function of this protein?
Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine.  Isoform 2 is essential for hearing.
What are the official names of this protein?
Methionine-R-sulfoxide reductase B3, MsrB3.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum. SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion.
Protein: EFTS_MAGMM
Sequence: MAVTASMVKELREKTGVGMMDCKKALAETGGDMEAAVDWLRKKGMASAQKKSARVAAEGKVTTLSLGSVGVMLEVNAETDFTAKNDNFCTFADTATKLAADNGCTDIDTLKALDYPGTGRNVGDELTNLIATIGENMNLRRIERMEVSSGLVSSYIHAGGKIGVLVALESTASADALQELGKKLAMHVAAAAPQFLNRDSVDSEAMEREKSVLIDQARASGKPDNIIEKMIVGRMDKYYADVCLLEQAYVIDPDHKVQQVVDAAAKELGCPVKVTGYARFQLGEGIEKKEEDFAAEVAKVVQG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.