PharMolix/UniProtQA huggingface dataset:
Protein: GLMU_ALIFM
Sequence: MNFSAVILAAGKGTRMYSNKPKVLHTLAGKPMAKHVIDTCEGLGAQNIHLVYGHGGDQMKAELGEERVQWVLQAEQLGTGHAVNQAAPEFADDEKVLVLYGDVPLISAETVENLLDAQPTGGIALLTVVLDNPMGYGRIIRRNGPVIAIVEQKDATEEQKLIKEINTGVMVATGGDLKRWLAALKNENAQGEYYLTDIIAAAHDEGRAVEAVHPVSPIEVEGVNDRAQLARLERAYQAAQAQKLLEQGVMLRDPSRFDLRGTLQCGMDIEIDANVIIEGNVTLGDNVVIGAGCVLKDCEIDDNTVLRPYSVIEGATVGEECTVGPFTRLRPGAELCNDAHVGNFVEVKNVRLGEGSKANHLTYLGDAEIGKRVNVGAGVITCNYDGANKFKTIIGDDVFVGSDSQLIAPVTVANGATVGAGSTVTKDVNENELYISRAKERRIANWQRPTKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_SYNR3
Sequence: MDRTIDDPVEASENDWRSKLTPEQFRITREGGTERAFTGAYWNHKGDGMYRCICCGAELFRSDRKFDSGTGWPSFWEGVNPEAIRTIQDVSHGMVRTEIRCAKCDSHLGHVFQDSPTPTGLRYCVNSASLDFKDKT
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: DCXR_HUMAN
Sequence: MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose.  Participates in the uronate cycle of glucose metabolism.  May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
What are the official names of this protein?
L-xylulose reductase, XR, Carbonyl reductase II, Dicarbonyl/L-xylulose reductase, Kidney dicarbonyl reductase, kiDCR, Short chain dehydrogenase/reductase family 20C member 1, Sperm surface protein P34H.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Probably recruited to membranes via an interaction with phosphatidylinositol.
Protein: PFKA_MYCLE
Sequence: MRIGILTGGGDCPGLNAVIRAIVRTCDARYGSSVVGFQDGWRGLLENRRMQLCNDDRNDRLLAKGGTMLGTAHVHPDKLRAGLHQIKQTLDDNGIDVLIPIGGEGTLTAAHWLSQEDVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEAIDRLHSTAESHQRVMLVEVMGRHAGWIALSSGLASGAHMTLIPEQPFDVEEVCCLVKRRFQRGDSHFICVVAEGAKPVPGSITLRQGGMDEFGHERFTGVAAQLGAEVEKRINKDVRVTVLGHVQRGGTPTAFDRVLATRFGVNAADASHAGEYGQMVSLRGQDIGRVPLEDAVRQLKLVPESRYDDAAAFFG
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFH_ECOLC
Sequence: MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRTDIDLTKNKVGIYSRPAKLSDSVHDGDRVEIYRPLIADPKELRRQRAEKSANK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: MOSB_AZOVD
Sequence: MANSTAELEELLMQRSLTDPQLQAAAAAAADFRILPDATVIKIGGQSVIDRGRAAVYPLVDEIVAARKNHKLLIGTGAGTRARHLYSIAAGLGLPAGVLAQLGSSVADQNAAMLGQLLAKHGIPVVGGAGLSAVPLSLAEVNAVVFSGMPPYKLWMRPAAEGVIPPYRTDAGCFLLAEQFGCKQMIFVKDEDGLYTANPKTSKDATFIPRISVDEMKAKGLHDSILEFPVLDLLQSAQHVREVQVVNGLVPGNLTRALAGEHVGTIITAS
What is the function of this protein?
Intracellular storage of molybdenum.  Binds polyoxomolybdates.  Can bind at least 90 molybdenum atoms per protein molecule.
What are the official names of this protein?
Molybdenum storage protein subunit beta, Mo storage protein subunit beta, MoSto subunit beta.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family. Highly divergent.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_BURMA
Sequence: MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAADGSLDRAKMRALVFSDESARKRLEAITHPLIREETEREARTAQGAYVVFVVPLLVESGTWKTRVDRVLVVDCDVETQIARVTARNGFTRAQVEAIVARQASRDARLAAADDVIANDNASVAELAAEVAALHQRYLECAAAARN
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAID_ECOSM
Sequence: MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGVVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMPVEEAYRYIRSGVLKNYPSVLHSEDAIEGPLAFAEKRDPVWKGR
What is the function of this protein?
Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
What are the official names of this protein?
Carnitinyl-CoA dehydratase, Crotonobetainyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: ILVD_BACP2
Sequence: MAELRSNMIKQGIDRAPHRSLLRAAGVKDEDFGKPFIAVCNSYIDIVPGHVHLQEFGKIVKEAIREAGGVPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADSVETVVSAHWFDGMVCIPNCDKITPGMMMAAMRVNIPTVFVSGGPMEAGRTSDGRKISLSSVFEGVGAYQSGKINEEELNELEQFGCPTCGSCSGMFTANSMNCLAEALGIALPGNGTILATSPERREFAKKSAKQLMELIKKDIKPRDIVTEKAIDNAFALDMALGGSTNTVLHTLAIANEAGVEYSLERINEVAERVPHLSKLAPASDVYIEDLHEAGGVTAALNELSKKEGALHLDTMTVTAKTLGENIAGHEVKDYNVIYPIDKPFTEKGGLAVLFGNLAPDGAIIKTGGVQDGITRHEGPAIVFESQEEALEGIINRKVEAGHVVIIRYEGPKGGPGMPEMLAPTSQIVGMGLGPKVALITDGRFSGASRGLSIGHVSPEAAEGGPLAFVENGDHVVVDIEQRILSVDVPEEEWEKRKANWKGFEPKVKTGYLARYSKLVTSANTGGIMKI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: THI4_PYRAR
Sequence: MELKIGRAIIKKGLEVLYEYSDVDVAIVGAGPSGLTAARYLAEKGFKVLVFERRFSFGGGIGPGGNMLPSIVVQEEALPILRDFKVRYQPAGDGLYTVDPAELIAKLAAGAIDAGAKIILGVHVDDVIFRGDPPRVAGLLWIWTPIQMSGMHVDPLYTMAKAVIDATGHDAEVISVAARKVPELGIQLPGEKSAWSEVSEKLVVEYTGKVAPGLYVTGMAVAAVHGLPRMGPIFGGMMLSGKKIAEIVAKDLAEEAYALRA
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: SYDND_CHLAA
Sequence: MYRSHTCGELRPAHAGQEVTLAGWVHRRRDHGDLIFIDLRDRYGITQVVFNSAHPTAHEVAETVRSEYVLQVRGKVRIRPPEAVNPDLATGEIELEASEAQVLNPARTPPIYIAKEGGEDESVRLKYRYLDLRRERMQRNLILRHRVVKFIRDFLDAEGFLEIETPILIKSTPEGARDYLVPSRLHPGKFYALPQSPQQLKQLLMVAGYDKYFQIARCFRDEDQRADRQPEFTQLDMEMSFVDQDDVLDLIERMFTALCRTVVPHKHLPTPFRRLSYAEAMERYGSDKPDLRYGLELVNLSDLLIETPFQVFRNVLNSGGQVKGIRAPGCAHFSRKQIDELTDVVRAGGAKGLAWAVLPTDGGEVRSSFAKNLAPGEFAAIVERMQAEAGDLLLIVADQPAVVAASLDKLRRNLAERLQLADPNTLCFAWIVDFPLVEWNEDEQRWDAVHHPFTAPKDEDMHLLATDPGKVRAKAYDLILNGYEAGGGSIRIHRRDVQQQIFSLLGISEELAQAQFGHMLEAFEYGAPPHGGIAPGIDRLVMILADEPTIREVMAFPKTQQAVDLMTNAPSPVDERQLKELHIRIVMPE
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLGD_ECOL6
Sequence: MKVTFEQLKAAFNRVLISRGVDNETADACAEMFARTTESGVYSHGVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGMSIVLDMIATLLSDGASVAEVTEDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL
What is the function of this protein?
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
What are the official names of this protein?
2,3-diketo-L-gulonate reductase, 2,3-DKG reductase, 3-dehydro-L-gulonate 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHAPP_DROSI
Sequence: TSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKPPAHFQHASDGPGGGVIQGSASEAVLVAVLAAREQAVASYRESHPELSESEVRGRLVAYSSDQSNSCIEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDANKVVDSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHIELAKQFEQLVLKDSRFELVAPSALGLV
What is the function of this protein?
Catalyzes the decarboxylation-oxidative deamination of L-3,4-dihydroxyphenylalanine (L-DOPA) to 3,4-dihydroxylphenylacetaldehyde (DHPAA) (By similarity).  Involved in cuticle development (By similarity).  Probably responsible for the protein cross-linking during the development of flexible cuticles (By similarity).
What are the official names of this protein?
3,4-dihydroxyphenylacetaldehyde synthase 2, DHPAA synthase, DOPAL synthase, Alpha-methyldopa resistant protein, AMD-r protein.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: PNP_CLOPS
Sequence: MNHTHETIIAGRPMKVEFGKLGMLSDAAILMSYGDTVILTNVNASEKPREGIDFFPLSVEYEERLYSVGKIPGGFIKREGKPSEKAILNGRAIDRPLRPLFPKGYRNDVQVVCTVVSVENDNLPEILAINAASMALCLSSIPFTTPVAAVQVGLIGEEFILNPTSKEREESSLQLTVCATKERVMMIEAGGDEIPEDTMINAIKFGFDKCQDIIKFQEEAVSMFGKEKKVPELHKVPEEIEEAVREFAFDMISESMHITDRDERNAAMDEVKAKINEEFEEKYPDNMSDIGEAVYDMQKEVVRHMLLKEGKRPDGRAFDEVRNIGCEVGLLPRTHGTGLFTRGLTQVMTVATLGAISEIQILDGIGEEESKRYMHHYNFPAYSVGEVRPLRGPGRREIGHGALAERALEPLIPSEAEFPYTIRLVSEVLSSNGSTSQASVCGSTLALLDAGVPIKRPAAGIAMGLITSKDLTEEEVLTDIQGLEDFFGDMDFKVAGTEEGITSIQVDTKIKGLSEKVIHDAIYGARKARLMILDKIKECIPAPREEVSKYAPKTSTLQIDPEKIRDVIGAGGKVINKIIADTGVKIDIKEDGLVYVSSAESEGVKEAVKIIEGLTKEVKSGEIYLGKVTKIAQFGAFVEVLPNKEGLVHISKLDNKRVEKVEDIVSVGDEILVKVTEIDSQGRINLSRKDAIKEAEEENKQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_SERP5
Sequence: MAIVKCKPTSPGRRHVVKVVNPELHKGKPHAPLLEKLSKSGGRNNNGRITTRHIGGGHKQHYRLVDFKRNKDGVAAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKVGNALPMRNIPVGSTVHNVEMKPGKGGQIARSAGAYVQIVARDGSYVTLRLRSGEMRKVPVDCRATLGEVGNAEHMLRVLGKAGAARWRGIRPTVRGTAMNPVDHPHGGGEGKNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: UBA5_RAT
Sequence: MAESVERLLQRVEELEQELARERSRRIAGDGHCGRTRIQKMSDEVVDSNPYSRLMALKRMGVVSDYEKIRTYAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQPYQAGMSKVQAAEHTLRSINPDVLFEVHNYNITTVEHFEHFMNRISNGGLEEGQPVDLVLSCVDNFEARMAINTACNELGQTWMESGVSENAVSGHIQLMVPGESACFACAPPLVVASNIDEKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLKFGTVSFYLGYNAMQDFFPTMFMKPNPQCDDKNCRKQQEEYKKRAPAQPTQETAPQEEEEVVHEDNEWGIELVSEVSEEELKNSSGPVPTLPEGITVAYTVPKKREDSVSEVTVEDSGESLEDLMARMKKM
What is the function of this protein?
E1-like enzyme which specifically catalyzes the first step in ufmylation.  Activates UFM1 by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a UFM1-E1 thioester and free AMP.  Activates UFM1 via a trans-binding mechanism, in which UFM1 interacts with distinct sites in both subunits of the UBA5 homodimer.  Trans-binding also promotes stabilization of the UBA5 homodimer, and enhances ATP-binding.  Transfer of UFM1 from UBA5 to the E2-like enzyme UFC1 also takes place using a trans mechanism.  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (By similarity).  Ufmylation is essential for erythroid differentiation of both megakaryocytes and erythrocytes (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5, UFM1-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Golgi apparatus. Note=Localizes mainly in the cytoplasm, while it localizes to the nucleus in presence of SUMO2. Interaction with GABARAPL2 promotes localization to the endoplasmic reticulum membrane.
Protein: ILVC_THEYD
Sequence: MKIYYDTDVNTDILKGKKIAIIGYGSQGHAHANNLKDSGFDVIVGVRKGKSWEKAENAGLTVMTVADASKMADIIMILTPDELQADLYKNEIEPNIKKGAFLAFAHGFNIHFGQIVPSSDINIFMVAPKGPGHLVRSEYLKGMGVPCLMAVHQDPSGITKDVALAYAVGIGGGRAGIIETTFKDETETDLFGEQVVLCGGLTALITAAYETLVEAGYPPELAYFECLHEVKLIADLIYEGGISTMRYSISNTAQYGDLTRGPRVINSSVKAEMKKILNEIQSGQFAKEWILECKVGKPTFNALTKQGEEHPIEKVGEKLRAMMPWLKSSKLVDKSKA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: NU4C_LOLPR
Sequence: MSYFPWLTILVVLPIFAGSLIFFLPHRGNKIVRWYTISICLLEFLLMTYAFCYHFQLEDPLIQLKEDYKWIDIFDFHWRLGIDGLSLGSILLTGFITTLATLAAWPVTRNSRLFYFLMLAMYSGQIGLFSSRDLLLFFIMWELELIPVYLLLSMWGGKRRLYSATKFILYTAGGSIFFLIGVLGMGLYGYGSNELGLDLERLINQSYPATLEILLYFGFLIAYAVKLPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLIRINMELLPHAHYLFSPWLVIIGAIQIIYAASTSLGQRNFKKRIAYSSISHMGFIIIGIGSITNIGLNGAILQILSHGFIGATLFFLAGTASDRMRLVYLEELGGISIPMPKIFTMFSSFSMASLALPGMSGFVAELVVFFGLITSPKFLLMPKMLITFVMAIGMILTPIYLLSMLRQMFYGYKLFNVPNANFVDSGPRELFILICIFLPVIGIGIYPDFVLSLSIDRVEALVSNYYPK
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRIM9_RAT
Sequence: MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSRRASGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPPTHLSPALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRTMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVAADGYILELDDGSGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIIFSNDNLTVTCSSYDDRVVLGKTGFSKGVHYWELTIDRYDNHPDPAFGVARIDVMKDMMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKTLTFFVNNEQQGPIAFENVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
What is the function of this protein?
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation.  May play a role in regulation of neuronal functions (By similarity).  May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM9, RING-type E3 ubiquitin transferase TRIM9, SNAP-25-interacting RING finger protein, Tripartite motif-containing protein 9.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Synapse. Cytoplasm, cytoskeleton. Cytoplasm. Cell projection, dendrite. Note=Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum (By similarity). Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle-associated form. Associated with the cytoskeleton (PubMed:11524423).
Protein: RS13_CELJU
Sequence: MARIAGVNIPDNKHAVISLTYVYGIGRTTAKQICAATGIAEDTKIGTLSEEQMDAIRAEVGKHTVEGDLRREINMNIKRLMDLGCYRGLRHRRGLPLRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RIFK_METM6
Sequence: MEIFGNVVSGLGEGSFFVGLTPYKYKFKELTGFTPFEGTLNVKLKHNFNLDEFNPIEFDGFEIDGKKYFGGKVLLIKLFNKSGHSIDCAIVAPKKTDHSKKTLEIIAPIQLRKFLSLKNFDVVKIVI
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.
Protein: SIR6_DROME
Sequence: MSCNYADGLSAYDNKGILGAPESFDSDEVVAEKCQELAELIKKSGHVVLHTGAGISTSAGIPDFRGPKGVWTLEEKGEKPDFNVSFDEARPTKTHMAIIALIESGYVQYVISQNIDGLHLKSGLDRKYLSELHGNIYIEQCKKCRRQFVSPSAVETVGQKSLQRACKSSMDSKGRSCRSGILYDNVLDWEHDLPENDLEMGVMHSTVADLNIALGTTLQIVPSGDLPLKNLKCGGKFVICNLQPTKHDKKANLIISSYVDVVLSKVCKLLGVEIPEYSEASDPTKQSKPMEWTIPTSNVNTFHRQYKKYVYFIYYLL
What is the function of this protein?
NAD-dependent histone deacylase that acts as a regulator of life span.
What are the official names of this protein?
NAD-dependent protein deacetylase Sirt6, Regulatory protein SIR2 homolog 6, dSirt6, SIR2-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class IV subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Predominantly nuclear; associated with chromatin.
Protein: EF1A1_TRYB2
Sequence: MGKEKVHMNLVVVGHVDAGKSTATGHLIYKCGGIDKRTIEKFEKEAADIGKASFKYAWVLDKLKAERERGITIDIALWKFESPKSVFTIIDAPGHRDFIKNMITGTSQADAAILIIASAQGEFEAGISKDGQTREHALLAFTLGVKQMVVCCNKMDDKTVNYGQERYDEIVKEVSAYIKKVGYNVEKVRFVPISGWQGDNMIEKSEKMPWYKGPTLLEALDMLEPPVRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGVMKPGDVVTFAPANVTTEVKSIEMHHEQLAEATPGDNVGFNVKNVSVKDIRRGNVCGNTKNDPPKEAADFTAQVIILNHPGQIGNGYAPVLDCHTSHIACKFAEIESKIDRRSGKELEKAPKSIKSGDAAIVRMVPQKPMCVEVFNDYAPLGRFAVRDMRQTVAVGIIKAVTKKDGSGGKVTKAAVKASKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha 1, EF-1-alpha 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSR_OENOB
Sequence: MVEAIHRSTRIEFSKSSLAYNVQYTKQVSGAKTLWLAVKSNAYGHGLLQVSKIARECGVDGLAVSVLDEGIAIRQAGIDDFILILGPIDVKYAPIASKYHFLTTVSSLDWLKSADKILGKEKLSVNLAVDTGMNRIGVRSKKDLKDEIEFLQEHSDHFSYDGIFTHFASSDNPDDHYFQRQKNRWYELIDGLIMPRYVHVMNSGAAMYHSKELPGCNSIARVGTVVYGVEPSEGVLGPIDKLKPVFELKSALTFVKKIPAGEGISYGSKFVTSRDTWIGTLPIGYGDGWLAEYQDFQLLIDGQKCRQVGQIAMDQMMVALPHEYPIGTEVTLIGKSGKYENTLYDLHKHSGVPPWKITVAFSDRLKRMVVD
What is the function of this protein?
Catalyzes the interconversion of D-lysine and L-lysine.  Can also use arginine and ornithine, but not alanine.
What are the official names of this protein?
Lysine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: RR19_AGRST
Sequence: MTRKKTNPFVAHHLLAKIEKVNRKEEKETIVTWSRASSILPTMVGHTIAIHNGKEHIPIYITNPMVGRKLGEFVPTRHFTSYENARKDTKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RHAA_HALH5
Sequence: MSMKSQFERAKIEYGQWGIDVEEALERLKQVPISIHCWQGDDVGGFELSKGELSGGIDVTGDYPGKATTPEELRMDLEKALSLIPGKHRVNLHAIYAETDGKVVERDQLEPRHFEKWVRWAKRHGLGLDFNPTLFSHEKAKDGLTLAHPDQAIRQFWIDHCIASRKIGEYFGKELETPCLTNIWIPDGYKDTPSDRLTPRKRLKESLDQIFAAEINEAYNLDAVESKLFGIGSESYVVGSHEFYLSYALKNDKLCLLDTGHYHPTETVSNKISAMLLFHDKLALHVSRPVRWDSDHVVTFDDELREIALEIVRNDALDRVLIGLDFFDASINRIAAWTIGTRNVIKALLFAMLIPHKQLKEWQETGDYTRRLAVLEEFKTYPLGAIWNEYCERMNVPIKEEWLKEIAIYEKEVLLQRH
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.