PharMolix/UniProtQA huggingface dataset:
Protein: YL488_MIMIV
Sequence: MLTKNTNNFSNSSNDPLNLYLNKNYAALANSDLTKKIDSDGNTVVHKMAKNLDHDAFDSILKHNPTAFKYNVINTANKRSELPIHKAMETLQSGGDPDHGFIDYLINGLGANPNVPDASGRTITQVNPTTYNPTNPTGSTNVPGITHLPSNAVNDQSVKQLNDQVIKNIRNLAKTAEDNINKISPKLGQSLRDKGVTPDSITNAAKNVVDRMPMIDKFFGKQTANQVGTVSQVTGGDNNVEFLRQLTNHYSTLRGGRSTSDRSDMNRYDSFVAKNKNSILNNYDRQYNDTFSSTGGKANKKLGDINTEDINNLFTDDAQNENSDNSMNTWGGAKKTYGNKSRSNDNSDNNDDSDDSERDIIDRRQTTKYQNMFSSQERPRERNTKVDEIYRSFVKKIMDLLGVDEETAKLYRSAIKIDIGNKNPELRKWENDELKIQEMEKIFNNKQSLQNALDKIDMDQIKSEMSRRRDESNKRRDEKRKDREEKRRQKRSQRSDTRKQGIDSVTSDEATSDQTQSTDSNNTTQTASKKRTRKSTTSQSRVGPNNYLRSEDIIISTEN
What are the official names of this protein?
Uncharacterized protein L488.
What are the subcellular locations of this protein?
Virion.
Protein: NHAA_FLAPJ
Sequence: MKITGLFKEFFESEKSSGLFLISCTLFSLVIANSAIANSYLHFWHANLAGNSLEYWINDGLMTIFFLLIGLELEREVYDGELSNIKDAMLPIFGAIGGMIVPAGLFLVMNFGTKTQSGAGIPMATDIAFALAILSLLGNKIPLSLKIFLTALAVIDDLGAILIIAVFYTKTLLWTNLCIALGIFGFLLILNRLKIRNLIPYLIGGVFMWYFMLHSGVHATITGVLLAFAIPFGNGDSRSTSYILQHFLHKPVAFFILPLFALANTAIVLSSNISETLIQNYSIGIALGLIIGKPLGIFLLSMLAVSLGICKLPDDLNWKSILAVGFLGGIGFTMSIFITLLAFNDDTIINNAKFVILISSLIAGIIGYFSLKYVLKNTIIENKN
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOB_CHLTE
Sequence: MKVADATPTPCIDFSKIQSIINPPDLLKVQLDSFHNFIQDSVPLEKRKDQGLEKVLRSAFPITDTRGLYLLEYISYSFDKPKYTVEECIERGLTYDVSLKIKLKLSYKDEADEPDWKETIQQEVYLGRIPYMTDRGTFIINGAERVVVAQLHRSPGVVFSEAVHPNGKKMYSAKIVPTRGSWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVEVSSKSSKREQLLGQYLASDIIDMTTGEVVPARAAITEEIIDQIVAAGYKTVKVMKTTSPEKGVDKSVIINTILNDSSATEEEALEIVYEELRSNEAPDIDAARSFLERTFFNQKKYDLGDVGRYRIQKKLQNELAELSAYLEKRPELKELSDAIYERILQTISTYSEEPIGEDILVLTHYDIIAVINYLIKLINGMAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDTDKIAPADLINARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAGFEVRDVHYTHYGRLCPIETPEGPNIGLISSLSVYAEINDKGFIQTPYRVVENGQVTDKVVMLSAEDEENKITVPVSIELDENNRIAAESVQARTKGDYPLVLAEEVNYMDVSPVQIVSAAAALIPFLEHDDGNRALMGANMQRQAVPLLVSEAPIVGTGMEAKVARDSRAVIVAEGPGVVQCVTADRIEVRYDLDPENNTVSLLDPDEGVKVYKLIKFKRSNQDTCISQRPLVHNGQRVNAGDVLADSSSTDNGELALGKNVLVAFMPWRGYNFEDAIVLSERLVYDDVFTSIHVHEFESSVRDTKRGEEQFTRDIYNVSEDALRNLDENGIVRIGAEVKERDILVGKITPKGESDPTPEEKLLRAIFGDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKIGMDVKERMEAIDKQFDLKEADLRSRFAKWMKQYLNGKKSVAITSDKGKVLVPEGTVIDEALLAKFNGLPFLESIDLSKGIVSGAKTNENVVRLIREYRLKLKDLSDERENEKYKINVGDELPPGIEELAKVYIAQKRKIQVGDKMAGRHGNKGVVGKILPIEDMPFMEDGTPVDIVLNPLGVPSRMNIGQLYETSLGWAGKKLGVKFKTPIFSGATYTEVQEYLEKAGLPGHGKVKLFDGRTGEQFHDEVTVGYIYMLKLSHLVDDKIHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLTVKSDDVIGRNKTYEAIVKGQNLPEPGTPESFNVLIRELQGLGLEIRIDDRVP
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PANB_FRATT
Sequence: MKSVLGFKKAKVTEKISMVTCYDYTLAKIINSTDIDCILVGDSGGMVLLGKKNTTYTTLDDMQFMTQAVANGATDKFIVADLPFMSYRQSLETTMQAVMALIQSGAHAIKLEGSSGNLDIIKHIVDSGVPVMGHIGMTPQFINSFGGFKVQGRTEEAAKHLLEEAKLLEQAGCFGIVLECIPANIAKDITQNLDIPTIGIGAGSNTDGQILVLQDMLGMNTDFQPKFVKKYIDGSKLFSDAINTYVKETKANTFPTKEHCYDYC
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5573_RHIME
Sequence: MRKVAILVAIVAAGLAGAWWFDLPARLGFAREPRQAVLYGNVDIRQVSLGFRVSGRIAELRVDEGDSVKAGDVIAKLDAEPFRQAVGAAEAEAEVTRATLAKLRAGARAAEIAQARATHEERLAELENAKLAFERAKQLRPNGTISQAELDQANASRAAADARARSAREALVLLEEGNRAEDIAAAAAQANAATAKADSARISLEDTQLAAPSDGVILSRVRETGAIVSPADIVYVLSLTEPVWVRAYVAEPDLGRVHPGMKVTITSDTAPDRIYEGTVGFISPVAEFTPKSVETPELRTDLVYRLRIVIANPGKDLRQGMPVTVHLPEAKEAS
What are the official names of this protein?
UPF0194 membrane protein RB0873.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VPC21_MYCTO
Sequence: MTTRYLLDKSAAYRAHLPAVRHRLEPLMERGLLARCGITDLEFGVSARSREDHRTLGTYRRDALEYVNTPDTVWVRAWEIQEALTDKGFHRSVKIPDLIIAAVAEHHGIPVMHYDQDFERIAAITRQPVEWVVAPGTA
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB21 (By similarity).
What are the official names of this protein?
Ribonuclease VapC21, RNase VapC21, Toxin VapC21.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: TYSY_BACC1
Sequence: MKHAENEYLNLCRHVMEHGTKKEDRTGTGTVSVFGYQMRFDLSKGFPLLTTKRVPFRLVASELLWFMKGDTNIRYLLQHNNNIWNEWAFKSWVESDEYTGPDMTDFGLRSQQDEEFKVQYDEQMELFKKNVLEDDDFSNKYGYLGDVYGKQWRAWKTTAGETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVPSMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTHLIAHECGLEVGEFVHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRKS3_ARATH
Sequence: MFAGIFLRMGAALRSMYVNSKYEEVREEWEEDYSPQRFSYKALYKATKGFKESELFGTEANGTVYKGKLSSNAQIAVKRVSLDAEQDTKHLVSQIVGIGKLRHKNLVQLLGYCRRKGELLLVYDYMPYGNLDDFLFNEERPNLSWSQRFHIIKGVASALLYLHEQIVLHRDVKAANVLLDEDLNGRLDYGLARFGTNRNPMLGSVGYVAPELIITGMPTTKADVYSFGALLLEFACGRMFIEYPGKPEEFNLISWVCQCWKRGNLVGARDARLEGDYVCKEIEMVLKLGLLCAQYNPEDRPSMSQVVNYLEGNDVLPEMPPDTPGISIPTPYHEVLA
What are the official names of this protein?
Receptor like protein kinase S.3, LecRK-S.3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: ADRO_DROME
Sequence: MGINCLNIFRRGLHTSSARLQVIQSTTPTKRICIVGAGPAGFYAAQLILKQLDNCVVDVVEKLPVPFGLVRFGVAPDHPEVKNVINTFTKTAEHPRLRYFGNISLGTDVSLRELRDRYHAVLLTYGADQDRQLELENEQLDNVISARKFVAWYNGLPGAENLAPDLSGRDVTIVGQGNVAVDVARMLLSPLDALKTTDTTEYALEALSCSQVERVHLVGRRGPLQAAFTIKELREMLKLPNVDTRWRTEDFSGIDMQLDKLQRPRKRLTELMLKSLKEQGRISGSKQFLPIFLRAPKAIAPGEMEFSVTELQQEAAVPTSSTERLPSHLILRSIGYKSSCVDTGINFDTRRGRVHNINGRILKDDATGEVDPGLYVAGWLGTGPTGVIVTTMNGAFAVAKTICDDINTNALDTSSVKPGYDADGKRVVTWDGWQRINDFESAAGKAKGKPREKIVSIEEMLRVAGV
What is the function of this protein?
Required for synthesis of steroid hormones, for olfactory sensory behavior and completion of the second larval molt (a steroid mediated developmental transition) and pupariation.
What are the official names of this protein?
NADPH:adrenodoxin oxidoreductase, mitochondrial, AR, Adrenodoxin reductase, Ferredoxin--NADP(+) reductase, Ferredoxin reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: FOLD_RICAH
Sequence: MNNIIDGKALANEILEDLKLEIQELKSQTNASPKLAIVLVGDNPASIIYVKNKIKNAHKIGIDTLLVNLSTTIHTNDLITKINELNHDNEISGMIVQLPLPNSIDKNKILSAVSPYKDVDGFHPLNVGYLHSGIIDVSEFSQSFIPCTALGCLAVIKKYEPNLSGKHVVVIGRSNIVGKPLSALLLKEDCSVTICHSKTHNLGSIALKADIVVAAIGSPLKLTAEYFNPESIVIDVGINRISGNKIIGDVDFEHVKSKVKYITPVPGGIGPMTIAFLLKNTVKAFKDSYSTVCHL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: GLGS_SHISS
Sequence: MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTWFCARYAWYCQQMMQARELELEH
What is the function of this protein?
Major determinant of cell surface composition.  Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
What are the official names of this protein?
Surface composition regulator.
What is the protein family that this protein belongs to?
Belongs to the GlgS family.
Protein: LEDL3_DROME
Sequence: MMVKLLLLFLVCWSALPLESSPLGNRYNLEIGEKQYYISLAKTNWFEASNHCRQNGGFLLNLESREELELLSPHLHPAYSYWLSINDLGERGVYVSEATGLEAPFLNWSAGEPDNSSGYDRCVELWLSTTSFQMNDLPCYSSVAFICQLN
What is the function of this protein?
Galactose-specific lectin that displays calcium-dependent activity (PubMed:16475980, PubMed:17287021).  Binds to the surface of hemocytes and enhances hemocyte encapsulation and melanization (PubMed:17287021).  This is likely by interacting with carbohydrates on the surface of the hemocytes (PubMed:17287021).  Also displays agglutination activity against the Gram-negative bacterium E. coli (PubMed:17287021).
What are the official names of this protein?
C-type lectin 37Db.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1569_LISMH
Sequence: MEYSYPLNPDWTTEEMTIVVQFLEAIERAYEKGIDTQELKDKYRAFKHVVPAKGEEKRIGIDFEKASGYSAYKVMQLVKNATTSKIKMQP
What are the official names of this protein?
UPF0223 protein LMHCC_1569.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: RNY_AQUAE
Sequence: MDVLSILLILVAVGVGIFVGRQFLGQKQAPAPTYQPVPSPQILEEAKSKAEEIIKEAKEKAEVILKEAKESAEKIVREAEEKAEKLIREAKEEVERIKEEVERRKKELKEREENVLAKERHLDRRWEALEKREEELLHRERELKDFERSLERWRDEIRHKEEELKHMKEEVEELKKKELEELQRIAKLTLEEARQEIIKKVEEEAKKDAVKLMKVIEEDAKRRAEFEAKKIIATATQRLAPQIAVNYTTTTVELPSNEFKGRIIGREGRNIRTFEILTGVDLIIDDTPDIVTISSFDPLRREIAKEALQRLIADGRIHPARIEEVVDEVKREFDEKIRKIGEETVYELDLHDINPGLYYYIGKLYFRTSYSQNVLLHSKEVAYIAGLMAEELGLDAKLARRAGLLHDIGKAISHELGGSHTDIGVELARKYGEPDAVINAIRAHHEEEPVRYPEVALVCAADALSAARPGARRETLEAYIRRLEKLEEIVKSFKGVANAYAVQAGREVRVIVNPEEISDEEAYLLSKEIPKKIEEELDFPGQIKVVVIRETRHVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CYF_CHAGL
Sequence: MQNRNFFEYPKNWIILLIPIFTTFNLLFTSDCYAFPIYAQQNYENPREATGRIVCANCHLAKGPVDIEVPKTVFPDTVFEAVVKIPYDTQIKQVLANGKKGGLNVGAVLILPEGFQLAPSDRIPAEIKEKIGNLAFQPYSEDKKNLLVIGPIPGKTYQEIIFPILSPDPNVNKESNFLKYPIYVGGNRGRGQVYPDGSKSNNNVFNSPATGKITKIVDNKKAGFELSITTVDGSSIVEIIPPGATFLVSEGDSVKIDQPLTTNPNVGGFGQADGEIVLQDPARLQGLLVFLFLVVLAQVFLVLKKKQYEKVQLAEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MUKF_ECO81
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMVLRDEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: KI26A_MOUSE
Sequence: MVGRGASLCAVQPAVAECGPARETPPLEVSPRKRLPAGLDQDPCSSRPAPEGAGASAEQSHSAGGGGWCRHCHTKLVELKRQAWKLVSGPGTPLRDPCLSTLLLDKLPASGVQPACRPDTESRCDVCTTHLHQLTREALRLLQTPASHEDPNASRGGLAAPSSRDPPGPVGLMGRQPPVGPDRRKATAWPPGPSVQVSVAPAGLGGALSTVTIQAQQCLEGVWSLSRVNSFLPPTCLAEAAVAAVAVADTVRDCAPAAGPERMSKAWGRGAACTTALVTPAPGTSAGGSTGPSAAASFFIRAAQKLSLASKRKKHHPPPAPSTRGTSTYPTDFSGSLQLWPPPVPPCLLRAASKAKENPSSFGKVKVMLRIWPAQGVQRSAESTSFLKVDSRKKQVTLYDPAAGPPGCAGLRHAPTAPVPKMFAFDAIFPQDSEQAEVCSGTVADVLQSVVSGADGCIFSFGHMSLGKSYTMIGKDSSPQSLGIVPCAISWLFRLIDERKERLGTRFSIRVSAVEVCGHDQSLRDLLAEVASGSLQDTQSPGVYLREDPVCGTQLQNQNELRAPTAEKAAFYLDAALAARSTSRAGCGEEARRSSHMLFTLHVYQYRVEKCGQGGMSGGRSRLHLIDLGSCDAAVGRGGEASGGPLCLSLSALGSVILALVNGAKHVPYRDHRLTMLLRESLATTNCRTTMIAHISDSPAHHAETLSTVQLAARIHRLRRKKGKHASSSSGGESSCEEGRARRPPHLRPFHPRAVVLDPDRSAPGLSGDPDYSSSSEQSCDTVIYVGPGGMALSDRELTDNEGPPDFVPIIPALSRRRPSEGPRDADHFRCSTFAELQERLECIDGSEAFPGPQGGSDGAQASPARGGRKPSLPEATPSRKAVAPTVVTSCPRGSPGHDTHRSASDPSKTGTQSEQRVDGSRPEPPASDKTSGGGGRRPLPSPAPPPPRQPEAQGIPKEPGGEGTDSVLRTPPVGMSGQAALPPLLSDSAYLSPSARGRHLERGLLTTTVTLQQPVELNGEDELVFTVVEELPLGGLAGATRPSSLASMSSDCSLQALASGSRPVSIISSINDEFDAYTSQMSEGPGDPGEFPEGTAWAGGSPASSIGSWLSDVGVCLSESRGPTPQPPFSPNSAAGPGPPEFPTPGSSLEESKVRSSECGRPDNPGSARSLHPGEAVATTQTQPGREPWARSPHEVASAQTIHSSLPRKPRTTSTASRARPSRGPYSPGGLFEDPWLLRAEDCDTRQIASTGRAPSPTPGSPRLPETQMMLACAQRVVDGCEVASRMSRRPEAVARIPPLRRGATTLGVTTPAASCGDAPAEAVVHSGSLKTTSGSKKSVSPKGAFFPRPSGAGPPAPPVRKSSLEQSTALTPTQALGLTRAGAPSAFRGEEEARPSGRSDSSVPKATSSLKARAGKMDVPYRPSGHMSLERCEGLAHGSSKVRDVVGRPPRAVPRLGVPSASPPLGPAPACRNSPAKGVGATKPPAGGAKGRNLGPSTSRALGAPVKPLGPVAGKTAGGAVPGPRAAPRAVPGIGAKAGRGTIMGTKQAFRAAHSRVHELAASGSPSRGGLSWGSTDSDSGNDSGVNLAEERQPSSPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAPDSMSESGTASLGARSRSLKSPKKRATGLQRRRLIPAPLPDAAALGRKPSLPGQWVDLPPPLAGSLKEPFEIKVYEIDDVERLQRHRLPLRENEAKPSQDAEKGPVCISSKLRLAERRQQRLQEVQAKRDHLCEELAETQGRLMVEPGRWLEQFEVDPELEPESAEYLVALEQATAALEQCVNLCKAHVMMVTCFDIGVAATTAVPGPQEVDV
What is the function of this protein?
Atypical kinesin that plays a key role in enteric neuron development.  Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling.  Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (PubMed:19914172).  Plays a critical role in cerebral cortical development.  It probably acts as a microtubule stabilizer that regulates neurite growth and radial migration of cortical excitatory neurons (PubMed:36228617).
What are the official names of this protein?
Kinesin-like protein KIF26A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF26 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MURA_DESAH
Sequence: MDKIEIRGGKRLTGEVRISGAKNAALPLLASSILVDGAMTFTNVPDLVDVRSIKMLLRDLGAGCEEGEGTVLIDGSGIHKIEAAYELVRKMRASILVLGPLVARFGHARVSLPGGCAIGARPVDMHLKGLKALGATITIENGYIEAKADRLKGNEIYFDIPTVTGTENLMMAATLAKGTTVLRNCAREPEITALANALNLMGARVTGAGTAVIRINGVDGLSPATIHVIPDRIEAGTFMVAAAATGGDVLVTGCEPENMGGIINKLRQTGALVEIIDHGVKVSGGKSILSTDIKTLPYPGFPTDMQAQFMVLMAISQGNSVIHETIFENRFMHVNELQRMGADISISGGNYAMVRGVNALSGAEVMASDLRASASLVIAGLVARGVTTIHRVYHIDRGYEALEKKFSALGADIKRVK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_ECOSE
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_MYCGA
Sequence: MRNSRKVLMGVVVSDKMQKTATVKVESKNRHPFYHKLVISHKKYHVHNEEGENAAKVGDKVLIMETRPLSATKRWRIAKIIERAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: IRX5_XENTR
Sequence: MSYPQGYLYQPSASLALYSCPAYSTTVISGPRTDELGRSPSGSAFSPYAGSTAFTASSAGFNSPLQYSGDPAAAFTSYVGSPYDHSAGMAGSLGYHPYAAPLGTYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEDDENIDLEKNEEDDPRKLEEKGDQDGDAGDQKRSPSAVDFDRLEGEVRQGKELDQTRSDSEQNEVEERNDLLSKNSAPPTSPLCPPDQSPQAQEDQNLHRHTVHNHHHQSIQQLHHHSHQSHPLDLVHRNALVQHGPVTNNATSVIHSPPASTSKPKLWSLAEIATSSDKVKESSDAAAVAGTTPAQSMVVSASSPSRSPSAQCHFPSNTVLSRPLYYSNPFYPGYTNYGTFSHLHSHHGPSTTSPTVNSTHHFSGINQTVLNRAEALAKECKLRSQSQADLNKDTPYEMKKGMSSI
What is the function of this protein?
Acts partially redundantly with other irx members in neural patterning.  Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord.  Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes.  Does not appear to play a role in pronephros kidney development.  Involved in craniofacial and gonadal development (By similarity).  Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12.
What are the official names of this protein?
Iroquois-class homeodomain protein irx-5, Iroquois homeobox protein 5.
What is the protein family that this protein belongs to?
Belongs to the TALE/IRO homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DER_SYNS9
Sequence: MARPVVAIIGRPNVGKSTLVNRLCRSREAIVHDQPGVTRDRTYQDGYWGDREFKVVDTGGLVFDDDSEFLPEIREQAALALDEASVALVIVDGKQGLTAADESIAEFLRQQRCPTLLAVNKCESVEQGLAMAAEFWSLGLGEPYPISAIHGAGTAEVLDQVLTFLPPKDQEGDEEEPIQMSIIGRPNVGKSSLLNAICGEQRAIVSPIRGTTRDTIDTNIVRENRPWRLVDTAGIRRRRSVNYGPEYFGINRSFKAIERSDVCVLVIDALDGVTEQDQRLAGRIEEDGRACVVVVNKWDAVEKDSHTMSATEKELRAKLYFLDWAPMLFTSALTGQRVESIFALAALAVEQHRRRVTTSVVNEVLKEALSWRSPPTTRGGRQGKLYYGTQVASRPPSFTLFVNDPKLFGDTYRRYVERHIREGLGFDGTPLKLFWRGKQQRDAEKELARQQNRRG
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SUR8_CULQU
Sequence: MGLCHSNCPFVEQKCHRIKVSRPTEGGVWPTTNGFSLDHTTKSAKTLGRTRTTSPKTNERGMNLGSSGGTSTSGHTSSGYSSGNAPGTSSSSTGGGATSSEMPAEIRPKVVTVKHPESNKPKPTTKKGKAIQADVDVIKEFQRCKEENILRLDLSKSSITVIPPSVKDCTSLIEFYLYGNKISSLPVEIGCLSNLKTLALNENSLTSLPDSLQNLKALKVLDLRHNKLSEIPDVIYKLHTLTTLYLRFNRIKVVGDNLKNLSSLTMLSLRENKIHELPAAIGHLRNLTTLDLSHNHLKHLPEAIGNCVNLTALDLQHNDLLDIPETIGNLANLQRLGLRYNQLTAIPVSLRNCIHMDEFNVEGNSISQLPDGLLASLSNLTTITLSRNAFHSYPSGGPAQFTNVTSINMEHNQIDKIQYGIFSRAKGLTKLNMKENALTSLPLDIGTWSQMVELNFGTNSLAKLPDDIHCLQNLEILILSNNMLKRIPNTIGNLKKLRVLDLEENRLESLPSEIGLLHDLQKLILQSNALQSLPRTIGHLTNLTYLSVGENNLQYLPEEIGTLENLESLYINDNASLVKLPYELALCQNLAIMSIENCPLSALPPEVVGGGPSLVIQYLKLHSPYRQM
What is the function of this protein?
Acts as a Ras effector and participates in MAPK pathway activation.  Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity).
What are the official names of this protein?
Leucine-rich repeat protein soc-2 homolog, Protein Sur-8 homolog, Protein soc-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
Protein: RS17_SALAI
Sequence: MSENTTATTRARRKVREGLVVSDKMEKTVVVEVEDRVKHALYGKIMRRTSKLKVHDEQNSAGIGDRVLIMETRPLSATKRWRLVEILEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y919_METJA
Sequence: MLEKLKKLLSKKGDNFSTPAPVSVDDYLEEIEEIPLTPVEEEKVIIKVCSIEDEKDAVNAIVMAEAGYIVIAKTPNLEKEIDDEFIEIIRKMRNEVAKFGGMLLALGDEHLLITPRNVVIEKLIKEKKEESNVTKENIEIKEEKEENSE
What are the official names of this protein?
Uncharacterized protein MJ0919.
Protein: RL7_MARSD
Sequence: MADITKDQVVEFISNMTVLELSEFITELEEKFGVSAAAPVAAVAAMPGAAGGEAAGGEEQTEFDVILKSAGGNKIAVIKAVRALTGLGLKEAKAKVDEAPAAIKEGVEKAEAEEALKQLEEAGAEAEMK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: FDHE_SHIF8
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELAENNPLGDYLRFAALIAHAQKVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKHWQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAVADDLASLVLDARMEQEGYARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.