PharMolix/UniProtQA huggingface dataset:
Protein: NUON_RHOP5
Sequence: MTAAQLFALSPLAALAIGAVIAMLLAPVTKSAAAARIAAATGLAVAALLEILRAGVPPAPIGALFTDDGLARYGTAYAALFGLAALVFLRVAGVAKEAPALVALVALGAASLTGAGHAATLFLGLELISLSLIALFAFPLTGMALEASYKFLVMSGLATSAQLLGVALIYAETGALDFPGWVGHGPLFALGTALLLAGLAFKFSLAPFHMWTPDAFQGAPAGAAALAGVVSKAAVAIAILRLNSEAQLPQPLWSAGLATLGAASVLVGNVLALRQQLLPRMLGYSTIAHSGYIAMILASGAPGTNEAVLFYLGIYAPALTATLCASAMLGPAPMLEDLRGLARKRPLEATSLSVGLLSLAGLPVAGGFVAKLYLFKALVQSESWILLAIAMVGAALGFYYYIRFFTAPFFGHGGIEPAPRHRFDRLLLIFCFGLIMLFGFEPLVLITAVNSALAVR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXS_BARHE
Sequence: MSRTLTPLLDRVCEPQDLRAFPESDLARLADELRAETIDVVSVTGGHLGAGLGVIELTVALHYVFNTPEDRIIWDVGHQAYPHKILTGRREKIRTLRQEGGLSGFTKRSESVYDPFGAGHSSTSISAGLGMAVASALKAEKRRNIVAVIGDGAMSAGMAYEAMNNAGALNARLIVVLNDNDMSIAPPTGAMSAHLARLVSRPAYRSLRERVKVLGEKLPKFFLDKARRSEEFARGFLVGGTLFEELGFYYVGPIDGHNLKHLLPVLKNVREYPTGPVLIHVVTHKGKGYAPAEASLDKYHGVNRFDIITGKQVKASSNVLPYTKVFSKALREEASYDDKIVAITAAMPTGTGLDFFAEKFPERMFDVGIAEQHAVTFAAGMACEGYKPFVAIYSTFLQRAYDQIIHDVSIQKLPVRFAIDRAGFVGADGATHAGSFDIVFLTTLPEFVVMAPSDEVELMHMVRTAAAYDQGPISFRYPRGEGIGMDLPQRGEILEIGKGRILHEGNRIALVCFGTRISEVLVAADELSAEGLSTTVADARFAKPLDKDLMRRLAREHEVLVTIEEGAIGGFGAHLLQFLAQEGLLEHGLKVRTLKLPDEYLNHGSQEKVLSRIGLDAVGIVNTVFSALGRKIRTVQRVRV
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: CBY2_HUMAN
Sequence: MSPLECSECFGDQLLHRTYTWQLTLHSRPNYTRKRDTRSESLEIPISVVLPQRGTAEPFPRLHNLYSTPRCAQQAALPRLSRRMASQHSYPLNRFSSVPLDPMERPMSQADLELDYNPPRVQLSDEMFVFQDGRWVNENCRLQSPYFSPSASFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLRAEHRGFQEENKALWENNKLKLQQKLVIDTVTEVTARMEMLIEELYAFMPARSQDPKKPSRV
What are the official names of this protein?
Protein chibby homolog 2, Spermatid-associated protein.
What is the protein family that this protein belongs to?
Belongs to the chibby family. SPERT subfamily.
Protein: NORM_BRUSU
Sequence: MDGTFDAGFREPTISKANRWGREMVVALKLGWPLIFTNLSQAALTATDVIFIGRLGADTLASALLATSFYHTLMIFSMGLVSAVMPMIAIALGKNRHSVRDVRRTVRQGFWSAIMIVIPLWVVLWHCEEIFLFLGQRPDIAARSTDFMHTLQWALLPYLFYIVLRSFFAAMEKPMWTLLVAALAIGFNALAGWTLIFGHFGFAPMGLHGAGMATTASSTMMFLGLAFITLRHPRFRRYHLFGRFWRPDWPRLIELWRIGLPMALTFVFETSIFYAAVVMMGRIGPTAMAAHAVAIQIASLSFMVPLGFGQVATVRVGRAYGRGDPKAIAYAGWSAYALGVGFMALMGILMVLMPRVFIGIFLNLNDPQNLPVMELAVTFLALAALFQIVDGAQAVAAGMLRGLRDTRIPMLLALFGYWGVGLPLGAVLAFQFGMGGVGIWLGLAAGLGMVAVLMTIRWRRHLAHVSAVAAA
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSAB_TRICV
Sequence: MATKFPKFSQALAQDPATRRIWYGIATAHDLEAHDGMTEENLYQKIFASHFGHLAVIFLWTAGNLFHVAWQGNFEQWVAKPLKVRPIAHSIWDPHFGESALKAFSKGNTYPVNIAFSGVYQWWYTIGFRTNQELYLGSVGLLLLSCALLFAGWLHLQPKFRPSLSWFKNNESRLNHHLSGLMGVSSLAWTGHLVHVALPASRGVHVGWDNFLTTPPHPAGLTPFFTGNWTVYAQNPDSPSHVYGTSEGAGTRILTFLGGFHPQTQSLWLSDIAHHQLAIAFVFIIAGHMYRTNFGIGHNMKEILDAHRPPGGRLGAGHVGLFETITNSLHIQLGLALACLGVATSLTAQHMYALTPYAYLSKDFTTEAALYTHHQYIAGFLMVGAFAHGAIFFVRDYDPELNKNNVLARMLEHKEAIISHLSWASLFLGFHVLGLYIHNDTVVAFGQPEKQILFEPLFAEYIQAASGKAVYNFNVLLSSSTNPATIAGNQVWLPGWLEAINNSKTDLFLKIGPGDFLVHHAIALGLHVTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAMFWMLNTIGWVTFYWHWKHMTIWGGNPGQFDESSNYIMGWLRDYLWLNSSPLINGYNPFGMNNLSVWAWMFLFGHLIWATGFMFLISWRGYWQELIETLVWAHERTPLANLIRWRDKPVALSIVQARLVGLVHFAVGYILTYAAFVIASTSGKFA
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SERC5_MOUSE
Sequence: MSARCCAGQLACCCGSAGCSLCCGCCPKFRQSRTTRFMYLFYFILVIALCCVMMTPSVMKQVKDHIPFFEEFCKKTQAGGDACENLVGYSAVYRVCFGMACFFALFCLLTLKVNNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLKVWRYVGAGGSFLFICIQLLLIVQFAHKWNKNWTAGTVRNKLWYASLSLVTLIMYSVAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLVAISPCVQNRQPHSGLLQSGLISCYVTYLTFSALTSKPEKKVLDEHGKNVTICAPDFGQDLHRDENMVTWLGTLLLIVCISYSCLTSTTRSSSDALQSRYGAPELEVARCCFCFGPDGEDTEEQQNVKKGPRVIYDEKKGTVYSYSYFHFVFFLASLYVMMTLTSWFHYENATIKTFFSGWSVFWVKMASCWMCVLLYLQTLVAPLCCPSRQFSV
What is the function of this protein?
Restriction factor required to restrict infectivity of gammaretroviruses: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm (By similarity).  Enhances the incorporation of serine into phosphatidylserine and sphingolipids.  May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity).
What are the official names of this protein?
Serine incorporator 5, Axotomy-induced glycoprotein 3, AIGP-3.
What is the protein family that this protein belongs to?
Belongs to the TDE1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to the cell membrane, where it is efficiently incorporated into budding gammaretrovirus virions and impairs subsequent virion penetration of susceptible target cells.
Protein: PSD_RHIL3
Sequence: MSLFNTVRNTIVPVHKEGYPFVAAFFVASLVLGWIFKPLFWIGMIFTLWCAYFFRDPERVTPQDDDLVISPADGKVSAIQMVTPPAELNLGSEPMLRISVFMNVFNCHVNRAPMHGRIVSINYRSGSFVNAELDKASEDNERNGLVIETGHGQIGVVQIAGLVARRILCWANPNEPVDAGERFGLIRFGSRLDVFLPAGAAPRVSLGQTAVAGETVIAEFASAKGPVISRRS
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NPRL2_HUMAN
Sequence: MGSGCRIECIFFSEFHPTLGPKITYQVPEDFISRELFDTVQVYIITKPELQNKLITVTAMEKKLIGCPVCIEHKKYSRNALLFNLGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVSMEESKQKLVPIMTILLEELNASGRCTLPIDESNTIHLKVIEQRPDPPVAQEYDVPVFTKDKEDFFNSQWDLTTQQILPYIDGFRHIQKISAEADVELNLVRIAIQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKRASLRDVFQLYCSLSPGTTVRDLIGRHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVTREEQSHPARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICWK
What is the function of this protein?
Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling.  Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at 'Tyr-9', 'Tyr-373' and 'Tyr-376' residues.  May act as a tumor suppressor.  Suppresses cell growth and enhances sensitivity to various anticancer drugs.
What are the official names of this protein?
GATOR complex protein NPRL2, Gene 21 protein, G21 protein, Nitrogen permease regulator 2-like protein, NPR2-like protein, Tumor suppressor candidate 4.
What is the protein family that this protein belongs to?
Belongs to the NPR2 family.
What are the subcellular locations of this protein?
Lysosome membrane. Note=Localization to lysosomes is amino acid-independent.
Protein: YGS9_SCHPO
Sequence: MEIHGKNFLETLKELEKHVDSAHYVSIDCEFSGLLRDFNLNNKNTLQDRYELLRKSSIRYTILQIGITFIYLQNNGKSSCIPVNINVSPLVKDELHLKRDFCSEASSIKFLIQQGFDFNKQLTEGVPYLSRIEERNLIDKVNERSTDDLTSSILDACDEEILVDARNQIKNWLSSELSHSTSKYLNITTSNRFIRKAIQSLVKIEFPTLKSYPKRTFLQVRKAIENSTTQCSATSKSELKEDIASDQLILNNLNLIKQNVGLRHLWDYILKKKKSVVCHNGMADLVYLFSLFEGKVPETILEFSELCLSSFKSIYDTKLLYLKSDDLQHVSDGIPTDLLSLVSKISLPPVPSNSSSQRSNVSLNSLIECPYKSMMSRKRPHEAGKDSYDTALLFVYYVMRTKHSDIQRWQNVLPIHGSFLDLNKYCS
What are the official names of this protein?
Uncharacterized protein C29A10.09c.
What is the protein family that this protein belongs to?
Belongs to the CAF1 family.
Protein: SODM2_LEPBY
Sequence: MAFELKPLPYAYDALEPYIDATTMQLHHDKHHAAYVNNLNAAIEKYSDLQSMSVEDLVTHLDRVPEDVRTTVRNNAGGHVNHTMFWEIMGANGSGAPTGAISEAINNSFGSFDAFKQQFNDAGTKRFGSGWVWLVRSQQGDLQILSTPNQDSPLIEGHTPIMGNDVWEHAYYLKYQNRRPEYLNAWWNVLNWEEINRRFDAAMSGH
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn] 2.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: YER7_SCHPO
Sequence: MLVRENNSNDRSIIEYVIKILLISGISRIIILILAMFESIRHIIFHNDTNPSDARKFQMAICRLSSQKSRKLKNPIESSTTSHKKKGYVRKCYECLQIQVS
What are the official names of this protein?
Uncharacterized protein C2F3.07c.
Protein: G6PI_CITK8
Sequence: MKNINPTQTSAWQALQKHYDDMKDVTIADLFAKDSDRFTRFSATFDDLMLVDFSKNRITEETLAKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHVALRNRSNTPIIVDGKDVMPEVNAVLEKMKAFSEAIISGQWKGYTGKAITDVVNIGIGGSDLGPFMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLSTANDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIILSVGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNAVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPSQLEHVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGAILNIFTFDQWGVELGKQLANRILPELGDDKAISSHDSSTNGLINRYKAWRA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_PORGI
Sequence: MQEIPEKPLSQPAGTEIIEKYFPHLSERQREQFEQMGGLYTHWNALINVISRKDIDNLYLHHVLHSLGIARMLNFKPGTSVLDLGTGGGFPGIPLAILFPQVSFLLVDSIGKKVKVASAVAEALGLDNVRTMHCRAESIGEKFDFIVSRAVMKLSELAKICRKLIRREDQQNALPNGLICLKGGELQHEILPFRNKAMTEELWPTFEEEYFKTKKVVYLPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRRC4_HUMAN
Sequence: MKLLWQVTVHHHTWNAILLPFVYLTAQVWILCAAIAAAASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWLAWWLREYIPTNSTCCGRCHAPMHMRGRYLVEVDQASFQCSAPFIMDAPRDLNISEGRMAELKCRTPPMSSVKWLLPNGTVLSHASRHPRISVLNDGTLNFSHVLLSDTGVYTCMVTNVAGNSNASAYLNVSTAELNTSNYSFFTTVTVETTEISPEDTTRKYKPVPTTSTGYQPAYTTSTTVLIQTTRVPKQVAVPATDTTDKMQTSLDEVMKTTKIIIGCFVAVTLLAAAMLIVFYKLRKRHQQRSTVTAARTVEIIQVDEDIPAATSAAATAAPSGVSGEGAVVLPTIHDHINYNTYKPAHGAHWTENSLGNSLHPTVTTISEPYIIQTHTKDKVQETQI
What is the function of this protein?
Synaptic adhesion protein.  Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins.  Organize the lamina/pathway-specific differentiation of dendrites.  Plays an important role for auditory synaptic responses.  Involved in the suppression of glioma (By similarity).
What are the official names of this protein?
Leucine-rich repeat-containing protein 4, Brain tumor-associated protein BAG, Nasopharyngeal carcinoma-associated gene 14 protein, Netrin-G2 ligand, NGL-2.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Postsynaptic cell membrane. Note=LRRC4 and DLG4 are interdependent for synaptic localization.
Protein: LPXA_ECOSM
Sequence: MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDFC_BACSU
Sequence: MRKKTVQIMISHSLMIGLWASAFPGIRAGLEGYTPEHLALFRLLIGSMALLLFAVLTQMRLPDLKDIPAIFLLGFLGFAFYHILLNIGEKTVSAGVASLLVTTAPIFSAMLSRLFYKEHFGFTKWLGSMISLLGVLLIAFGAGDFTYSMSGILVILLAAFSESIYFVFQARYIKKYGFIPFVTFTIWGGTIPMLVFLPGLGEEMMNASISATLSIVYLGLLPTVIPYFALAYVTSFVGASEATLSLYVTPALALIISWLWIGEIPTLLSLLGGVVTVGGVCFTYLKVNKMNKIFITHFSAKRVKKL
What are the official names of this protein?
Uncharacterized transporter YdfC.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPOL_HHV6U
Sequence: MDSVSFFNPYLEANRLKKKSRSSYIRILPRGIMHDGAAGLIKDVCDSEPRMFYRDRQYLLSKEMTWPSLDIARSKDYDHMRMKFHIYDAVETLMFTDSIENLPFQYRHFVIPSGTVIRMFGRTEDGEKICVNVFGQEQYFYCECVDGRSLKATINNLMLTGEVKMSCSFVIEPADKLSLYGYNANTVVNLFKVSFGNFYVSQRIGKILQNEGFVVYEIDVDVLTRFFVDNGFLSFGWYNVKKYIPQDMGKGSNLEVEINCHVSDLVSLEDVNWPLYGCWSFDIECLGQNGNFPDAENLGDIVIQISVISFDTEGDRDERHLFTLGTCEKIDGVHIYEFASEFELLLGFFIFLRIESPEFITGYNINNFDLKYLCIRMDKIYHYDIGCFSKLKNGKIGISVPHEQYRKGFLQAQTKVFTSGVLYLDMYPVYSSKITAQNYKLDTIAKICLQQEKEQLSYKEIPKKFISGPSGRAVVGKYCLQDSVLVVRLFKQINYHFEVAEVARLAHVTARCVVFEGQQKKIFPCILTEAKRRNMILPSMVSSHNRQGIGYKGATVLEPKTGYYAVPTVVFDFQSLYPSIMMAHNLCYSTLVLDERQIAGLSESDILTVKLGDETHRFVKPCIRESVLGSLLKDWLAKRREVKAEMQNCSDPMMKLLLDKKQLALKTTCNSVYGVTGAAHGLLPCVAIAASVTCLGREMLCSTVDYVNSKMQSEQFFCEEFGLTSSDFTGDLEVEVIYGDTDSIFMSVRNMVNQSLRRIAPMIAKHITDRLFKSPIKLEFEKILCPLILICKKRYIGRQDDSLLIFKGVDLVRKTSCDFVKGVVKDIVDLLFFDEEVQTAAVEFSHMTQTQLREQGVPVGIHKILRRLCEAREELFQNRADVRHLMLSSVLSKEMAAYKQPNLAHLSVIRRLAQRKEEIPNVGDRIMYVLIAPSIGNKQTHNYELAEDPNYVIEHKIPIHAEKYFDQIIKAVTNAISPIFPKTDIKKEKLLLYLLPMKVYLDETFSAIAEVM
What are the official names of this protein?
DNA polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: OREX_MOUSE
Sequence: MNFPSTKVPWAAVTLLLLLLLPPALLSLGVDAQPLPDCCRQKTCSCRLYELLHGAGNHAAGILTLGKRRPGPPGLQGRLQRLLQANGNHAAGILTMGRRAGAELEPHPCSGRGCPTVTTTALAPRGGSGV
What is the function of this protein?
Binds to orexin receptor HCRTR2/OX2R only (By similarity).  Stimulates food intake (By similarity).  Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner (By similarity).
What are the official names of this protein?
Hypocretin neuropeptide precursor, Hypocretin, Hcrt, Orexin precursor, Prepro-orexin, Preprohypocretin.
What is the protein family that this protein belongs to?
Belongs to the orexin family.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum. Cytoplasmic vesicle. Synapse. Note=Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
Protein: GGGPS_CHIPD
Sequence: MHNKIYNSFIDRKAKGIKSFAVLIDPDKVNPADIADLAAKCTAAKVDYIFLGGSLVITNHLDECVQQFKTLCDIPVVLFPGSPSQVSRYADALLYLSVISGRNPELLIGQHVLSAPAVKKSGLEVISTGYVLIDGGAPTTVSYISNTTPIPSDKDDIAMCTAMAGEMLGMKVVFMDAGSGARKPITESMISRVASQVSAPIIVGGGIRDAEKAYLNCKAGADIIVVGNAIEKETSLIKEMADAVHAAAPVLK
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
Protein: ENGB_BURP0
Sequence: MAFLLHQARFFTTVNHLRDLPPTVQPEVAFAGRSNAGKSTAINVLCNQKRLAFASKTPGRTQHINYFSVGPAAEPVAHLVDLPGYGYAEVPGAAKAHWEQLLSSYLQTRPQLCGMILMMDARRPLTELDRRMIEWFAPTGKPIHSLLTKCDKLTRQESINALRATQKSLDAYRDAGYAGKLTVQLFSALKRTGLDDAHALIESWVRPAAADEDRAAVAE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RL34_STRS7
Sequence: MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: MNME_ACIBT
Sequence: MNNMHSQTTIAAIATPPGRGGVGVIRLSGPKAYDIAQKLTQKNLPEARMAGFRKFYDADGSIMDEGIVLCFPNPHSFTGEDVVELQGHGGPVIQNALLGRLFELGAIAAKAGEFSMRAFENGKMDLVQAEAIADLIDATSQAAARSAVRSLQGAFSTKINTVLEKLIYLRLHVEAAIDFPEEEIDFLADGKILALLEDVQQSVHAVQTSARQGQLLREGLQVVIAGKPNAGKSSLLNALAGVERAIVTDIAGTTRDVLHEKISLNGLPITLTDTAGLRETGDIVEKEGIRRAIKEIEQADLLLLVYDLNQGDDPLKLAQEYFSEHIEPRRLMLIGNKCDLTGQSAEISDYQGFRHITVSAKQEMGVQGLVDAITAHAGFHPEEDTFIARTRHLDAMKRTQLYLAEAREQLVVFNAGELVAESLRLAQNALGEITGDFSADDLLGKIFGSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPNE2_MOUSE
Sequence: MAYIPDGGAPTAGAIPLGSQCCVCKVELSVSGQNLLDRDVTSKSDPFCVLFIEDNGRWMEFDRTETAVNNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSSAQLDEHDFLGQFSCSLGTIVSSKKITRPLLLMNDKPAGKGVITIAAQELSDNRVITLSLAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDLEKPIQVMCYDYDSNGGHDFIGEFQTSVLQMSEARDGVPLEIECINPKKQRKKKSYKNSGIIILRSCKIHRNYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQQTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDNRRLRSHTGEEAARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNLPPTNSEPA
What is the function of this protein?
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes.  Exhibits calcium-dependent cell membrane binding properties (PubMed:21087455, PubMed:26175110).
What are the official names of this protein?
Copine-2, Copine II.
What is the protein family that this protein belongs to?
Belongs to the copine family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Translocates to the cell membrane and the nucleus in a calcium- dependent manner (PubMed:21087455, PubMed:26175110). Colocalizes with CD2 at the cell membrane (PubMed:21087455).
Protein: RECU_BACCR
Sequence: MTIRYPNGKRYNQASQPQKTPIKTHTYSNRGMSLEEELNETNQYYLTHNIACVHKKPTPLQIVKVDYPARSAAVVKEAYFKQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQIEHMKQVVAHNGIAFVIIKFTLFDEFYLLDAKHIIAFWNRQNTGGRKSITKEEIEEHGSLLSCGYHPRIDYIRVLDMVYFS
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TARJ2_STAA8
Sequence: MINQVYQLVAPRQFDVTYNNVDIYGNHVIVRPLYLSICAADQRYYTGRRDENVLRKKLPMSLVHEAVGEVVFDSKGVFEKGTKVVMVPNTPTEQHHIIAENYLASSYFRSSGYDGFMQDYVVMAHDRIVPLPNDIDLSTISYTELVSVSYHAIQRFERKSIPLKTSFGIWGDGNLGYITAILLRKLYPEAKTYVFGKTDYKLSHFSFVDDIFTVNQIPDDLKIDHAFECVGGKGSQVALQQIVEHISPEGSIALLGVSELPVEVNTRLVLEKGLTLIGSSRSGSKDFEQVVDLYRKYPDIVEKLALLKGHEINVCTMQDIVQAFEMDLSTSWGKTVLKWTI
What is the function of this protein?
Catalyzes the NADPH dependent reduction of D-ribulose 5-phosphate to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribulose-5-phosphate reductase 2, Ribulose-5-P reductase 2, Ribitol-5-phosphate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: ARLY_SULDN
Sequence: MDKMWSGRFSATASSLLDQFNASIMFDRKLYREDIEGSIAHATMLAKQGILTTDELSQITKGLSQVKEEIESGVFEWKISDEDLHMGIEKRLTAIIGDAGKKLHTARSRNDQVAVDFRRYVLRKNLEIVDALKLLMNEILVIASKHTQTLLPGMTHLQHAQPINFAFHLSAYLSMFKRDIERFESSYKRNNISPLGCAALAGTPHKIDRDMTAELLGFESASINCLDTVSDRDFALEILFNISTMMMHISRLSEELVMWSSYEFRFVELSDEYSTGSSIMPQKKNPDVPELLRGKTGRVYGSLMGLLTVMKALPLAYNKDTQEDKEGVFDAVETAEISLEILKEALKTMQVKPHYMKNACKIGHLSATDLADYLVQKCDIPFREAHFITGKAVAKSEELKIDLSDIELKYLKEIDDRINEDVLAFLSIENSMNARTSAGGTSTKRTEEQLKYFENFLKAE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_PROM0
Sequence: MILDNFFKNLIYEPVSVLGLLVFYFLLINLPISLGAVFKKKSSFAVRLITILVNLLITLQLLFRWSISGHFPISNLYESLYFLAWGITLGQLLVEREYQAPIIPSIAIPIELLIVSFACFVLPEDLKSSSNLVPALRSSWLVMHVSVVMLSYAALIIGSLLSMSVLFINKNKPLQIRSSSTGIGGFKLSNSYPVNDLVESIEFSHSEELDTLSYRSILIGFVLLTLGLISGAVWANEAWGTWWSWDPKETWAFISWLFYAAYLHMRISKGWQGRKPALLASTGFLVVLVCYLGVNFLGIGLHSYGWIFG
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.