PharMolix/UniProtQA huggingface dataset:
Protein: SPRL1_RAT
Sequence: MKAVLLLLYALGIAAAVPTTFLSDHSNPTSATLPTLEDATVPTVPAEAAADIEKHPNHKAEKPSALNSEEEAHEQSTEQDKTYSFEVDLKDEEDGDGDLSVDPTERTLDLQEGTSEPQQKRLPENADFPATVSTPFVDSDQPANITKGEESQEQPVSDSHQQQDESGKQTQDSMTEESHKQDPGIPNEEKEEEEDPEDVGAPSDNQEEEKEPPEEQPTSKWEGNGDQSEDILQESSQPTQISKTKNDFEQGSQGQEGDSNAEGEDKAAGSKEHLPHTEWQGQEGRAGLDAIGNRKDTDEEKAVSTEPTDAAVVPRNHGASDNGGGDDSKHGASDDYFIPSQEFLEAERMHSLSYYLKYGEETPDESENRSEAGDNQGAKKAESSPNAEPSDEGNSRGHSADSCMNFQCKRGHTCKTDQHGKPHCVCQDPETCPPAKILDQACGTDNQTYASSCHLFATKCMLEGTKKGHQLQLDYFGACKSIPACTDFEVAQFPLRMRDWLKNILMQLYEPNPKHGGYLNEKQRSKVKKIYLDEKRLLAGDHPIELLLRDFKKNYHMYVYPVHWQFNELDQHPADRILTHSELAPLRASLVPMEHCITRFFEECDPNKDKHITLKEWGHCFGIKEEDIDENLLF
What are the official names of this protein?
SPARC-like protein 1, Matrix glycoprotein Sc1.
What is the protein family that this protein belongs to?
Belongs to the SPARC family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: NUDL_ECO27
Sequence: MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: SEPS_METHJ
Sequence: MIFDTEEFKKRGKEDFESAWHAGPSVLTPPTTDLMYPRLTYLRAQAHPVFETIHRLREAYLAIGFQEAENPIIVDEQEVYRQFGPEAMAVLDRVFYLGGLPRPNVGIGKEQIQKINSILGRDLSEDEEESLRKTLHAYKKSEIDGDELAYELSGVLHTDDARIVEILDRVFPEFRALKPESSRQTLRSHMTSGWFQTLGAIWEKVPHPIRLFSIDRCFRREQAEDSHRLMSYHSASCVVAGEYVTIEDGKAVARALLSAFGYTDFEFRPDDKRSKYYMPDTQTEVYAAHPDHGWVEVATFGIYSPVALAEYGVGIPVMNLGLGVERMAMIMNKAKDVRELCFPQFFPIRYTDTELAAGVSLLAEPATTPGKNLVRSLINTAVTHSTAIGPCSFVAFEGEIAGKQIRVYVEEPEENAKLLGPACMNEIFVHKGAILGVPDTEKFAEVRKNGISTGISYLFAAASQAAAEIEQAAHFGIPTTVQIKMARLPGDINLKIEPWVMRYITDNNLKTDVRGPVFLTIRSEVLPTSEV
What is the function of this protein?
Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
What are the official names of this protein?
O-phosphoserine--tRNA(Cys) ligase, O-phosphoserine--tRNA ligase, Non-canonical O-phosphoseryl-tRNA(Cys) synthetase, O-phosphoseryl-tRNA(Cys) synthetase, SepRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
Protein: PPAC_STAAS
Sequence: MAKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQQDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED29_MOUSE
Sequence: MAAPQPQAAAVSSASGVSGPGSAGGPGPQQQPQPTQLVGSAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDNGQKSSDAPLQRFDKCLEEFYALCDQLELCLRLAHECLSQSCDSAKHSPTLVPTATKPDAVQPDSLPYPQYLAVIKAQITCAKDIHTALLDCANKVTGKTTAPSTGPGGSL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 29, Intersex-like protein, Mediator complex subunit 29.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 29 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS5_MYCLE
Sequence: MAAQSAGLLGDSREGRSRREGGSRGGRDRDRDGEKGNYLERVVAINRVSKVVKGGRRFSFTALVIVGDGHGMVGVGYGKAKEVPAAIAKGVEEARKSFFRVPLIDGTITHPVQGEAAAGVVLLRPASPGTGVIAGGAVRAVLECAGVHDILAKSLGSDNAINVVHATVAALKLLQRPDEVAARRGLRSGMLPRSWDPAGVAGERSVDRPVGRVREQA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: WRK71_ORYSI
Sequence: MDPWISTQPSLSLDLRVGLPATAAVAMVKPKVLVEEDFFHQQPLKKDPEVAALEAELKRMGAENRQLSEMLAAVAAKYEALQSQFSDMVTASANNGGGGGNNQSSTSEGGSVSPSRKRKSESLDDSPPPPPPPHPHAAPHHMHVMPGAAAAGYADQTECTSGEPCKRIREECKPKISKLYVHADPSDLSLVVKDGYQWRKYGQKVTKDNPCPRAYFRCSFAPACPVKKKVQRSAEDNTILVATYEGEHNHGQPPPPLQSAAQNSDGSGKSAGKPPHAPAAAPPAPVVPHRQHEPVVVNGEQQAAAASEMIRRNLAEQMAMTLTRDPSFKAALVTALSGRILELSPTKD
What is the function of this protein?
Transcription repressor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.  Represses specifically gibberellic acid (GA)-induced promoters in aleurone cells, probably by interfering with GAM1 (PubMed:15047897).  Regulates, probably indirectly, the activation of defense-related genes such as GF14E during defense response (By similarity).  Modulates plant innate immunity against X. oryzae pv.  oryzae (Xoo) (By similarity).  Confers resistance to the virulent bacterial pathogen X. oryzae pv.  oryzae (Xoo) 13751, probably via the regulation of NPR1 and PR1b defense signaling pathways (PubMed:16919842).
What are the official names of this protein?
WRKY transcription factor WRKY71, OsWRKY71.
What is the protein family that this protein belongs to?
Belongs to the WRKY group II-a family.
What are the subcellular locations of this protein?
Nucleus. Note=Localized in nuclei of aleurone cells.
Protein: TBL6_ARATH
Sequence: MERQRSFSVKSTRVLAFIITIISSAIVFFTFFSSSLLKSNSSLYPTPEANFQIDLSPIAAISDSSVSPQASPILISTHFNSPENTSGSSKISVFEQKISGESLVKEVREIANLTSIKVIELPSNNGEDKKTEKRIEECDVTKGKWVYDSDYPLYTNASCPFIDEGFGCQSNGRLDLNYMNWRWEPQDCHAPRFNATKMLEMIRGKRLVFVGDSINRNQWESMLCLLFQAVKDPKRVYETHNRRITKEKGNYSFRFVDYKCTVEFYVTHFLVREGRARIGKKRRETLRIDAMDRTSSRWKGANILVFNTAHWWSHYKTKSGVNYYQEGDLIHPKLDVSTAFKKALQTWSSWVDKNVDPKKTRVFFRSAAPSHFSGGEWNSGGHCREANMPLNQTFKPSYSSKKSIVEDVLKQMRTPVTLLNVSGLSQYRIDAHPSIYGTKPENRRSRAVQDCSHWCLPGVPDTWNHFLYLHLLHKR
What is the function of this protein?
May act as a bridging protein that binds pectin and other cell wall polysaccharides.  Probably involved in maintaining esterification of pectins (By similarity).  May be involved in the specific O-acetylation of cell wall polymers (By similarity).
What are the official names of this protein?
Protein trichome birefringence-like 6.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: NADE_STRSV
Sequence: MSLQEEIIAQLGVKPIIDPEEEIRKSVDFLKAYLKKHPFLKSYVLGISGGQDSTLAGRLAQLAVEEMRAETGDNSYRFIAVRLPYGVQVDEDDAQKALAFIQADVSLTVNIKESADAMTKAVEATGAKVSDFNKGNIKARSRMIAQYALAGSYSGAVIGTDHAAENVTAFFTKFGDGGADILPLYRLNKRQGKQLLAALGADPALYEKVPTADLEEEKPGIADEVALGVTYNEIDDYLEGKSVSAQAQETIESWWHKGQHKRHFPITVFDEFWR
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: YBBA_BACSU
Sequence: MKGSLSEHKAGNRRFTLYLPPSYSTDSGGFPAVYVQDGSSLFQNQIELLESAFQQQRLPELVLIGIEPENRLDEYTPWPAASLSDRFTDFGGMGYHYLSDITNQFIPLIEENWNVTREPQSRGMIGASLGGLISMFAILKYPSMFGKIGSISGSYWYENAAETIHISSLKPGTARVFMSIGSEEGREKQSIQRHMLKKTKQVHQSLKEKGFTEDQLCLSIEKGAVHHHKYFCKQFINALEWLYGKNRSTL
What are the official names of this protein?
Uncharacterized protein YbbA.
Protein: RL13_RHOCS
Sequence: MKTLSLKPSEIEKKWILIDADGLVLGRLASQIAMRLRGKHKPTYTPHMDCGDNVIVINAEKVKLTGNKRQDDIFYWHTGYPGGIKGRSKGQILDGRFPERVIIKAVERMVPRGPLGRRQMGNLRVYAGTAHPHEAQQPEVLDVAAMNPKNKRSA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RPOZ_FRATO
Sequence: MARVTVEDCLDKVETRFDLVVLASMRANKILKNGYSESMENEKKEKATVVALREIAESEITPEQILRNEIEG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: IL8_CHICK
Sequence: MNGKLGAVLALLLVSAALSQGRTLVKMGNELRCQCISTHSKFIHPKSIQDVKLTPSGPHCKNVEIIATLKDGREVCLDPTAPWVQLIVKALMAKAQLNSDAPL
What is the function of this protein?
May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src.  Chemotactic for peripheral blood mononuclear cells as well as for heterophils.
What are the official names of this protein?
Interleukin-8, IL-8, 9E3, C-X-C motif chemokine 8, CEF-4, Chemokine (C-X-C motif) ligand 8, Embryo fibroblast protein 1, EMF-1.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAA1_PORG3
Sequence: MITILGPTACGKTRLAVSLAYRLGTEIISADSRQIYRGMDIGTGKDLADYQVGGTTIPCHLIDIRPAGDKYNLFAYQHDFHQAYASILARGMDPILCGGTGMYIEAVLKGYHLPDVPPNPTLRDRLQGKSLTELTLILAAYGPLHNKTDVDSAQRAIRAIEIAEYIKNNPAESTEFPPIDSLIIGLDLDRDTRRKRITDRLHARMHEGMIEEVKGLLDSGIPADDLIYYGLEYKFVTLYLTGQTDYESMFTGLETAIHQFAKRQMTWFRGMERRGFLIHWIDALLPADEQCEAVMKLYTANG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 1, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 1, DMAPP:tRNA dimethylallyltransferase 1, DMATase 1, Isopentenyl-diphosphate:tRNA isopentenyltransferase 1, IPP transferase 1, IPPT 1, IPTase 1.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SET2_GIBZE
Sequence: MEDDEYTTSKMEEIKLEEGANDAQVKQETNTPMSITNGDHESSRSPTASQDGLKSRSESADTPSSNRPSKLSRKASQKLAASREPVLFDHLPDMTTESCKFFQRIPDCLYGSKHLGSTDNDALDCECRDEWHDGKNLACGEDSDCINRATKMECSAEGGNCAGGCQNQRFQRKQYANVSVIKTEKKGFGLRADSDLQPNDFVFEYIGEVINEPTFRRRMIQYDEEGIKHFYFMSLNKSEFVDATKKGNYGRFCNHSCNPNCYVDKWVVGDKLRMGIFTSRKIQSGEELVFNYNVDRYGADPQPCYCGEPNCVGFIGGKTQTERATKLPAATVEALGIDGGDGWDTSVAKKPRKKKPDEDDEEYVNSIRPRSLSEDDARKVMAALMQCKEKWIAVKLLDRIMQCDEERVIHCVMRMHAYQILKTTLNTFIDDHNVVLQVLDILDKFPRLTRNKVQDSKIEATIEGLTQSEHEDVASKSKHLLNEWSKLEVAYRIRRRKFDPNAPAANSFEERRGAGREEETVQSTSKTASPTPIDAPKGPRNSMPQRNNAFFQNGGRSRRPPFNASLPQGWFTAKDAAGNTYFYTKQGATTWQRPTQPATEPAAKAPSKAMKEQLAIQSIINQVTEKGTPKHTSVSTPKAAETPPKEVKEEKWRSLPVDKRMKIYENTLFPHIKHVLDKFHHKLPKEELKRFGKDIAKKLVASDFKNNRVEDPGAPLSDKQVKKIKQYVKDFLDRAVKKYGEHKRKADEDADTQMKDDQGPSAAGSGAGSVVDGSDGTALAKVDGTSMGEVDVTAVSDREGTGSLGSPDRKRKRDLDTSGSPYVTSTDGPNMKRLREDELEAPSPPPPPPPPPQSDMDEVVTAEQEALREQEEALMRENEEAQRLEDEASHTKGLEDVLDASNEISRLNKEARKPGSQKMPA
What is the function of this protein?
Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3.  Involved in transcription elongation as well as in transcription repression.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-36 specific, SET domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RUVC_STRAW
Sequence: MRVLGVDPGLTRCGVGVVEGVAGRPLTMRGVGVVRTPADAELGLRLVAIEQGIEQWLDEYRPECVAVERVFSQHNVRTVMGTAQASAVAMLCAARRGIPVALHTPSEVKAAVTGSGRADKAQVGAMVTRLLRLDAPPKPADAADALALAICHIWRAPAQNRLQQAVALHASKGRTA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: THAP1_BOVIN
Sequence: MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKKWEAAVRRKNFKPTKYSSICSEHFTPDCFKRECNNKLLKEDAVPTIFLCTEPHDKKEDLLEPQEQPPPPPLTPPISQVDAAIGLLMPPLQTPDNLSVFCDHNYTVEDTMHQRKRIHQLEQQVEKLRKKLKTAQQRCRRQERQLEKLKEVVHFQKEKDGASERGYVILPNDYFEIVEVPA
What is the function of this protein?
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression.  Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1.  May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis (By similarity).
What are the official names of this protein?
THAP domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the THAP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, PML body.
Protein: VE7_HPV55
Sequence: MHGNYPTLKEIVLELDPPDPVGLHCNEQLDSSEDEVDELATQATQDVTQPYQIVTTCGTCNRNVRLVVQCTGTDICQLHTLLLGSLEILCPVCAPKN
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: CH60_SHEAM
Sequence: MAAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLEKSFGAPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVAAAVVELKALSQECADSKAIAQVGTISANSDESIGDIIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGAVELDNPFVLLVDKKISNIRELLPILEGLAKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVIAEEIGLELEKATLEDLGTAKRVVITKDNTTIIDGNGAEEQIKARVGQIKQQIEETTSDYDREKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRVASKIANVDVANEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNFGYNAGNDSYGDMLEMGILDPTKVTRSALQFAASVAGLMITTEAMVAELPKADAPDMGGMGGGMGGMGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_GEMAT
Sequence: MIIGVLNGPNLNLLGTREPAVYGTATLADIMAHLEGVAGALGVQLRTAQSNSEGALIDILHDWRGVVDGVVVNAGAYTHTSLALRDAFTATAIPFIEVHLSNIHAREPERRHSMLASASIGMICGLGADGYEFGLRGLVRALELKRQSTATG
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: Y4NH_SINFN
Sequence: MNAVPIILVFAAGLNSCIGNILLKWGRASLPPSAGLADTFLTPGFVGGVVFYGINVLLFAKALDSLEVSVAYPILAGSGFAMLIIASHYFFGEPFHLHKWIGVALVLVGIIFLARGG
What are the official names of this protein?
Uncharacterized protein y4nH.
What is the protein family that this protein belongs to?
To E.coli and S.aureus ethidium bromide resistance proteins (ebr/QacC/EmrE/MvrC).
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIC_DEIGD
Sequence: MSAPTAPQTTLSTAPFPNSEKRYLIGTLYPQVRVPVRAIRQSATLEMIGGLTRQRPNPDVLVPDTSGPYTDPRIHIDLRRGLPHARPWLAADARLEVQAERLSAPLDGAGPLPFPAVPLSRRARSGQAITQMQAARRGEITPEMEFVALRENLRQAEAFELAQQHPGQSFGAAIPREITPEFVRAEVARGRAVIPANVNHPELEPTIIGRNFRVKVNANLGTSIVTSSIEEEVEKMVWATRWGADTVMDLSTGRHIHQTREWILRNSPVPVGTVPIYQALEKVGGVAEELTWEVYRDTLIEQAEQGVDYFTVHAGVRLAHIPLTARRRTGIVSRGGSILAKWCLAHHRENFLYTHFREICEILSAYDITFSLGDGLRPGSIEDANDAAQFAELDTLGELTRVAWEHGVQTMIEGPGHVPMQLIRENMTRQLQVCQEAPFYTLGPLTTDIAPGYDHITSAIGAAQIAWYGTAMLCYVTPKEHLGLPDRQDVRDGVIAYRIAAHAADLAKGHPGAQARDNALSQARFEFRWEDQFNLALDPERARALHDATLPADAAKTAHFCSMCGPHFCSMKLSHDLRADDILNGMAEKAREFRAAGGELYLDRPEGTP
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CYB_ALCAC
Sequence: MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGVCLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDADKIPFHPYYTIKDILGALLLTLFLMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVSSILILILMPLLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEYPFITIGQLASILYFLIILVLMPVTSTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HMUV_ENTCL
Sequence: MAERYTAENLTFTRSGRTLTDNVSLSLSQGELVTLIGPNGAGKSTLLRLLTGYLKPDSGGCSLAGKALDEWHPQTLSRYRAVMRQQSQPGFDWQVEEIVGMGRAPWTRHPEPSIVREVLQLTGCLPLAGRRYHALSGGEQQRVQLARALAQLGVTERRAAWLFLDEPTSALDLYHQQHLLRLLKSLTRQGHLHACVVLHDLNLAALWSDRILLLHNGRIVSQGIPETVLQADALAHWYGAQVHVGMTSGARRTAGFSRPLA
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CD209_HUMAN
Sequence: MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLVLQLLSFTLLAGLLVQVSKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGELPEKSKMQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICKKSAASCSRDEEQFLSPAPATPNPPPA
What is the function of this protein?
(Microbial infection) Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of bacterial pathogen antigens, including Leishmania pifanoi LPG, Lewis-x antigen in Helicobacter pylori LPS, mannose in Klebsiella pneumonae LPS, di-mannose and tri-mannose in Mycobacterium tuberculosis ManLAM and Lewis-x antigen in Schistosoma mansoni SEA (PubMed:16379498).  Recognition of M. tuberculosis by dendritic cells occurs partially via this molecule (PubMed:16092920, PubMed:21203928).
What are the official names of this protein?
CD209 antigen, C-type lectin domain family 4 member L, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single- pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane; Single- pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane; Single- pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 4]: Cell membrane; Single- pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 5]: Cell membrane; Single- pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 6]: Secreted. SUBCELLULAR LOCATION: [Isoform 7]: Secreted. SUBCELLULAR LOCATION: [Isoform 8]: Secreted. SUBCELLULAR LOCATION: [Isoform 9]: Secreted. SUBCELLULAR LOCATION: [Isoform 10]: Secreted. SUBCELLULAR LOCATION: [Isoform 11]: Secreted. SUBCELLULAR LOCATION: [Isoform 12]: Secreted.
Protein: IF1_NITMU
Sequence: MAKEETIQMQGEILETLPNATFRVKLENGHIVLGHISGKMRMHYIRILPGDKVTVDLTPYDLSRARITFRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.