PharMolix/UniProtQA huggingface dataset:
Protein: MNMG_ECOSE
Sequence: MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREASGEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSZ_HAEIG
Sequence: MLNLNELKSGFHYFVMGWHFITQKGLRRFVIMPIVLNTILLCGLFWLFISQISSAIDWMMNFIPDWLSFLSVILLTLSILTILLLFYFTFTTFSGFIAAPFNGLLAEKVEKMLTGENINDDGLVDIMRDVPRMLAREWQKLRYSLPKIIALFLLSFIPLVGQTIVPVLTFLFTCWMMAIQYCDYPFDNHKVSFDIMKNALGNQRTQSLTFGGLVTCCTFVPVINLLIMPVAVCGATLMWVENYRNDLGFNMNRSFSSQTGLDVRSENTGIVK
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PATR_LEIXX
Sequence: MRLRPEIVATPAYRQGRTAAADDFKLSSNENPYPPLASVVAAVGATLGGLNRYPDAGGADLRDKLAERHGVDVDQVHLGSGSVALLAQLIRAVAGAGDEVVYSWRSFEAYPGLATVAGATSVQVPNRADGGHDLPALAAAITDRTRAVIVCTLNNPTGPVVTAAEFASFMAEVPGDLLVLLDEAYHEFETDEAAVNGIPLLSRHPNLVVLRTFSKAYGLAALRIGYAVGPAAVLDAARSAALPLSVTDAARVAALASIEAEDELMERVARIAMRRDRLREALIEQGWSVPQAQGNFVWLATGEETAAASDAFSAAGLTVRAFPSEGIRISVGEHEYVERPVEVSADLGGKLPNGHPGKRLG
What is the function of this protein?
May catalyze the transamination reaction in phenylalanine biosynthesis.
What are the official names of this protein?
Putative phenylalanine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: MT1E_PIG
Sequence: MDPNCSCPTGGSCSCAGSCTCKACRCTSCKKSCCSCCPVGCAKCAQGCICKGASDKCSCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-1E, MT-1E, Metallothionein-IE, MT-IE.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: YJIB_BACSU
Sequence: MNVLNRRQALQRALLNGKNKQDAYHPFPWYESMRKDAPVSFDEENQVWSVFLYDDVKKVVGDKELFSSCMPQQTSSIGNSIINMDPPKHTKIRSVVNKAFTPRVMKQWEPRIQEITDELIQKFQGRSEFDLVHDFSYPLPVIVISELLGVPSAHMEQFKAWSDLLVSTPKDKSEEAEKAFLEERDKCEEELAAFFAGIIEEKRNKPEQDIISILVEAEETGEKLSGEELIPFCTLLLVAGNETTTNLISNAMYSILETPGVYEELRSHPELMPQAVEEALRFRAPAPVLRRIAKRDTEIGGHLIKEGDMVLAFVASANRDEAKFDRPHMFDIRRHPNPHIAFGHGIHFCLGAPLARLEANIALTSLISAFPHMECVSITPIENSVIYGLKSFRVKM
What are the official names of this protein?
Putative cytochrome P450 YjiB.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RS6_CHLTE
Sequence: MNTLKQYECTVIIDGGLQDDAIAAVMELVKKTVTDKGGVINNVLEVGRRKMAYLIRKTSIGYYAHIEFDAVPSVIAEIERVFRYEEAILRFLIIQLSSPLLEMRKRVEKYSVMLGSPEDQAEAEADADAKN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: COAA_SHEFN
Sequence: MNPINSIQDALYFAFQRKHWAELRKSVPLTLSQAELENLRGMNEKLSLDEVTDIYLPLSRLLNLFVGSKQQRGLVLDKFLEQKASPGPYIISIAGSVAVGKSTTARILQTLLQRWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFISAVKAGQKEILAPLYSHVTYDRCHDEHQAIRQPDILILEGLNVLQTGLDTPIDTRRPFVSDFVDFSIYVDADESLLKEWYKQRFLQFRKGAFSDPNSFFHHYSCLTDDEANTIAANIWDTINGPNLSLNIQPTRERANLILQKGPNHLMDRVLLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_SYNS9
Sequence: MESRPTTIGLVFGGYSGEHEVSIRSATTVIHGLRSGENSQRYRVIPFYIDQEGRWWGEAFANRVLASQKPIEPPHSIETKGFRELPEGSETVQVWYPVLHGPNGEDGTVQGLFQLMRQPFVGAGVLGSAVSMDKLAMKAAFAGAGLSQVPYVGLNASDLGDSARREHVLDRIEAELHYPCFVKPANLGSSVGISKVRNRHELETGLDHAAQLDPRLVVEQGVDARELECAVLGRHQLRSSVVGEVRFDADWYDYTTKYTAGLSTTVIPAELPEGVAERVQQQALEACAALGVVGMARVDFFYDNTSHQLWINEINTLPGFTSQSMYPMLWEASGVTLDQLVHKLVQSAGE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_SHIF8
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RGS2_MOUSE
Sequence: MQSAMFLAVQHDCVPMDKSAGNGPKVEEKREKMKRTLLKDWKTRLSYFLQNSSAPGKPKTGKKSKQQTFIKPSPEEAQLWAEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKSLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCKKPQITTEPHAT
What is the function of this protein?
Regulates G protein-coupled receptor signaling cascades.  Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (By similarity).  It is involved in the negative regulation of the angiotensin-activated signaling pathway (By similarity).  Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ.  Plays a role in regulating the constriction and relaxation of vascular smooth muscle (PubMed:14608379).  Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 2, RGS2.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus, nucleolus.
Protein: RSMJ_FRATW
Sequence: MQINISNLDVKNHLDKFIEDRLEYEFCKQDKYLYLENDNLKLHYNNKELFIDFNDSEILNRINPKTKKCSVVQAIEGRSKAKLTILDTTAGLGRDTFTLAARGHTLLTLEKDSYLYLLLKDALQRAQQINYLKEIANRITLINIDSNEYILTTDKSFDCVYVDPMFPPRKKSAKVKQGMQILHQVGFNDEVSNSNLLDNIIQTQISPKAVVKRPINAEFLSNKKPSSQLKGKTNRFDIYSL
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGF11_ANOGA
Sequence: MSENDGIHIEYVDEQELKREFRRFMSDPETREKAANYLYESLVDETILGIAYEVHHANKTGSGAAVEGEPEDSKPYTIVDQPDTDVFGSSNTKKAIDCHCPNCNRIVAASRFAPHLEKCMGMGRNSSRIASRRIANTRDVGTGNYFGGDEDDEDDADWSGEKRKKKISQVRTNGSKKNGKTS
What is the function of this protein?
Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B.  The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.
What are the official names of this protein?
SAGA-associated factor 11 homolog.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGB2_ARATH
Sequence: MVVIHGVSLTPRFTLPSRPLNTGFNAGNSTLSFFFKKHPLSRKIFAGKQSAEFDSSSQAISASEKVLVPDNLDDDPRGFSQIFDLESQTMEYTEAVRTEDQTMNVVKERGVKPRIVPPPGDGKKIYEIDPMLRTYNNHLDYRYGQYKRLREEIDKYEGGLEAFSRGYEKLGFSRSDAGITYREWAPGAKAASLIGDFNNWNSNADIMTRNEFGVWEIFLPNNTDGSPAIPHGSRVKIRMDTPSGIKDSIPAWIKFSVQAPGEIPFNGIYYDPPEEEKYVFKHPQPKRPKSLRIYEAHVGMSSTEPMVNTYANFRDDVLPRIKKLGYNAVQIMAIQEHSYYASFGYHVTNFFAPSSRCGTPEELKSLIDRAHELGLVVLMDIVHSHASKNTLDGLNMFDGTDAHYFHSGPRGYHWMWDSRLFNYGSWEVLRYLLSNARWWLEEYKFDGFRFDGVTSMMYTHHGLSVGFTGNYTEYFGLETDVDAVNYLMLVNDMIHGLYPEAITVGEDVSGMPTFCIPVQDGGVGFDYRLHMAIADKWIEMLKKRDEDWQMGDIIYTLTNRRWSEKCISYAESHDQALVGDKTIAFWLMDKDMYDFMAVDRPSTPLIDRGIALHKMIRLITMGLGGEGYLNFMGNEFGHPEWIDFPRGEQRLSDGSVIPGNNFSYDKCRRRFDLGDADYLRYRGLQEFDQAMQHLEENYGFMTSEHQFISRKDEADRVIVFERGDLVFVFNFHWTSSYFDYRIGCSKPGKYKIVLDSDDPLFGGFNRLDRKAEYFTYDGLYDERPCSFMVYAPCRTAVVYALANHD
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in starch by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan-branching enzyme 2-2, chloroplastic/amyloplastic, AtSBE II-2, Branching enzyme 2, AtBE2, Starch-branching enzyme 2-2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: TIR2_YEAST
Sequence: MAYIKIALLAAIAALASAQTQEEIDELNVILNDVKSNLQEYISLAEDSSSGFSLSSLPSGVLDIGLALASATDDSYTTLYSEVDFAAVSKMLTMVPWYSSRLLPELESLLGTSTTAASSTEASSAATSSAVASSSETTSSAVASSSEATSSAVASSSEASSSAATSSAVASSSEATSSTVASSTKAASSTKASSSAVSSAVASSTKASAISQISDGQVQATSTVSEQTENGAAKAVIGMGAGVMAAAAMLL
What is the function of this protein?
Component of the cell wall.
What are the official names of this protein?
Cold shock-induced protein TIR2, Serine-rich protein 2, TIP1-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Protein: RPIA_SHESH
Sequence: MTQDEMKKAAGWAALEYVEKDSIVGVGTGSTVNHFIDALATMKADIDGAVSSSEASTEKMKALGIPVYDLNSVDELSVYVDGADEINAHMDMIKGGGAALTREKIVAAVADKFICIVDNTKEVDVLGEFPLPVEVIPMARSYVARQLVKLGGDPVYREGVVTDNGNVILDVYNMKIMNPKELEEQINAIVGVVTNGLFAMRGADVLLVGSPEGVKTVK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: MSCL_DESVM
Sequence: MLKAFKEFAVKGNALDMAVGVILGASFGTIVKSLVDDLIMPPIGLVLGGVDFSNLFVTLRDGAAPGPYASLAAAKQAGAVTLNVGVFANTVVSFTIVAFAVFLLVRGVNTLRERLEGPAAPKQQACPFCFSKIDVRATRCPHCTATIG
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBSD_STAES
Sequence: MKKTAVLNSHISSAISTLGHYDLLTINDAGMPIPNDDKRIDLAVTKSLPRFIDVLETVLTEMEIQKVYLAEEIKTANAQQLKAIKKLINDDVEIKFIAHSEMKEMLKSPLNKGNIRTGEITPFSNIILESNVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_PASMU
Sequence: MRRFDTLFSQLQQKQQGAFVPFVTLCDPNLAQSFEIIQTLVENGADALELGFPFSDPMLDGPVIQAANQRALVAGCSTDASFQLLTQVRSTYPTLPISLLLCANLVYAQGIERFYQRCAEVGVDAVLIADLPLFAHREFTVMAEKYSIQQVFICPPNACEDTIKRVAQQTQGYTYLVSRSGVTGVENQQSADNLKTLVERLKAYQAPPILQGFGISQPQQVSDVLKIGVNGAISGSATVQIIEKYHHDPQACLAELAQFTQKMKQATT
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ADRK_PENRW
Sequence: MHPDSQLETAVKSGFDPKSLYSTELTKVNEPARTILEKYSKIPADNILQHVKDLRDRAFAFPYACIGQASFLELSIASSPCYPEMLDRVKKGDRLLDLGCAFGQELRQLIYDGAPSQNLYGSDLRPEFLELGLDLFMDRPTIKSRFIDADVLDDKSALVTQLTGELNIVYISLFLHVFDFDTQIKVAKRALELLAPKAGSLIVCRVVACRDQAIGNATNARLPYYYHDLASWNRLWERVQEETGLKLKVDNWEQDDALAKKHPLEGIYMLGSSIRRE
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of andrastins, meroterpenoid compounds that exhibit inhibitory activity against ras farnesyltransferase, suggesting that they could be promising leads for antitumor agents (Ref. 2).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase adrD via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Ref. 2).  DMAO is then converted to farnesyl-DMAO by the prenyltransferase adrG (Ref. 2).  The methyltransferase adrK catalyzes the methylation of the carboxyl group of farnesyl-DMAO to farnesyl-DMAO methyl ester which is further converted to epoxyfarnesyl-DMAO methyl ester by the FAD-dependent monooxygenase adrH (Ref. 2).  The terpene cyclase adrI then catalyzes the carbon skeletal rearrangement to generate the andrastin E, the first compound in the pathway having the andrastin scaffold, with the tetracyclic ring system (Ref. 2).  The post-cyclization tailoring enzymes adrF, adrE, adrJ, and adrA, are involved in the conversion of andrastin E into andrastin A.  The short chain dehydrogenase adrF is responsible for the oxidation of the C-3 a hydroxyl group of andrastin E to yield the corresponding ketone, andrastin D.  The ketoreductase adrE stereoselectively reduces the carbonyl moiety to reverse the stereochemistry of the C-3 position to yield andrastin F.  The acetyltransferase adrJ is the acetyltransferase that attaches the acetyl group to the C-3 hydroxyl group of andrastin F to yield andrastin C.  Finally, the cytochrome P450 monooxygenase adrA catalyzes two sequential oxidation reactions of the C-23 methyl group, to generate the corresponding alcohol andrastin B, and aldehyde andrastin A (Ref. 2).
What are the official names of this protein?
Methyltransferase adrK, Andrastin A biosynthesis cluster protein K.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily.
Protein: FABA_WIGBR
Sequence: MVKKHKFYTKEDLLCSSRGELFGKYGPQLPAPNMLMIDRLVKVTENGGNYNKGFIKAELDINPNMWFFSCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGKGKGRALGVREVKFSGQILPTSKIVVYYIHFRRIINRKLFMGMADGEVFCDGKIIYTANDLKVGLFQDITSFKKDFK
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_ANADF
Sequence: MPNVVVVGAQWGDEGKGKIVDLLTEHADVVVRFQGGNNAGHTLVVNGEKTVLHLIPAGILHPGKSCVIGNGVVFDPEVFVMEVDRLKSRNALADDSQLVVSLDAHVIMPWHKAIDIAREQAMGAGKIGTTGRGIGPTYEDKVARRGLRIRDLLDAARLERKVKERLPAAREELSRLGATPELDEAAIVARYSELGRRVARYAADVSLWLHRALQNGKQLLFEGAQGTMLDVDHGTYPFVTSSNTVAGNAVVGCGLGPTAVDYVLGISKAYSTRVGGGPYPSELKDETGERLRKIGGEFGATTGRPRRTGWLDALALRYAARVNGLHGIAMTKLDVLAGFETVKIAVGYRVDGKVLDEMPSDPELLERAEAVYEELPGWTEKLEDLRSWDDLPPRARAYVKRVEQLVGVPVVGLSVGADRGQTILLENPFRA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_RHIME
Sequence: MCPQPHADHAITRGDTGAAGGRNWSGPFRKTPGRLVGMTLIRAYQLTLSSFIGNSCRHLPTCSEYGFEAIARYGLWAGGWLTLFRVVRCGPGGTHGFDPVPDSLAPRQRWYTPWRYWQPRRKDA
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNH2_MYCCT
Sequence: MINRKSFDDQIKLDHNITYLSGSDEAGRGCLAGPLVVASVILKPDYFNPLIKDSKKLNPKTRQVLFDEIIKNCLDYQIMIISSKQVDELNPLQASLLGFKTTISNLKITPDLALIDGNQNINLENIKTLSIIKGDDNSFSIACSSILAKVTRDKILDQYDQIYPNYGFKSHKGYCTKKHLLAIQKYGVLDIHRKSYKPIKKISKETS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_NITOC
Sequence: MIGVSILGSTGSIGMSTLDVLARYPERYRVQALSANRSVAQIYQQCLQFRPSQVVMVDPDAAEQLRQRLHPVVPEIEVSSGSEALETIVTSPDTDYVMAAIVGAAGLLPTLAAARAGKRILLANKESLVMSGQLFMSAVSESGAELLPIDSEHNALWQCMPAEGRELPLHRKGVRRILLTASGGPFRERALSELDNVTPDEACAHPNWSMGRKISVDSATMMNKGLEVIEACWLFDAAACQIEVVLHPQSVIHSMVDYVDGSVLAQLGNPDMRTPIAYGLAWPERMESGVTLLDLFAIGQLTFCQPDLQRFPCLGLAYAALERGGTCSTILNAANEVAVQAFLDQRIQFTQIPKLIEWTLGRVTPTVADSLPAVLESDAVARQVAKEQVERWY
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: FDHE_SERP5
Sequence: MSIRIVPKEQLGAQREKSTTAETIPPLLFANLKSLYSRRAERLRKLATDNPLGDYLNFAAQLAEAQHHALHDNPLTLDLTEELQQGAASGKPPLDLSVFPRSEHWHKLLVSLIAELRPQAPEHILAVLDNLEKASSHELELLADALLNQDFGKIGSEKAPFIWAALSLYWAQMAGLIPGKARAEYGEHRQFCPVCGSIPVSSVVHIGTVSGLRYLHCNLCESEWHVVRIKCSNCEQTRDLNYWSLDSELAAVKAESCGDCGTYLKILYQEKDPQVEAVADDLATLVLDAKMEDEGFARSSINPFLFPGS
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_METCA
Sequence: MTEPVYKRILLKLSGEALMGDQGAGIDAEILKRLATEIDELCQAGVEVGLVIGGGNIVRGAEKASEGLDRVTGDHMGMLATVINALAMQDALENLGRPVRVMSALKINQVCEDYIRRRAVRHLEKGRVVVFAAGTGNPFFTTDSAASLRAIEIGADLLIKATKVDGVYSADPVKNPEAKFYTRLTYDEALDQRLNVMDTTALVLCRDYKMPLRVMNVFRQGAVMRLIRGDDIGSLLVTG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_ALISL
Sequence: MSRVAKAPVVLPAGVEVKLNGQEITIKGGKGELTRVLNNAVVVSQEDNSIVFGPREGVANAWAQAGTARALVNNMVVGVNEGFTKKLTLKGVGYRATMKGNAVGLTLGFSHPVEHALPEGIKAECPTQTEIIITGCDKQVVGQVAADIRSYRKPEPYKGKGVRYADEIVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: FUMC_PROMM
Sequence: MMADLMRIEHDSMGTIEVPAGVLWGAQTQRSLLNFAISTDRMPVELIHALALIKQAAASVNCRLGVLDEVQRDQIIKAASAVASGLHDDQFPLRVWQTGSGTHTNMNVNEVISNLASQANDEPLGSHRPVHPNDHVNRSQSTNDAFPTAIHIAAVQGITNNLLPELEQLIAAFARKSDAWSDIIKIGRTHLQDAVPLTLGQEASAWRDQIASAHSRIQSSLIELYPLPLGGTAVGTGLNAPARFGQETAAQLASITGLPFSSAKNKFAVMASHDGLVNAMAQLRMLAVALFKISNDLRLLACGPRAGLAELHLPENEPGSSIMPGKVNPSQCEAMAMVCLQVIGLDSAVTMAGGSGHLQMNVYKPLIGFNLLHSIELLHDACRKYRLAMVQGIEPNRIKIQHDLEQSLMLVTALAPEIGYDKASEIAHLAHEKGFSLREAALKLGYVSKEDFDRIVNPALMTSARL
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F200B_HUMAN
Sequence: MDHFFIKRKRNSEVKYTEACSSSSVESGIVNSDNIEKNTDSNLQTSTSFEPHFKKKKVSARRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESLKPSKLKRHLETQHAELIDKPLEYFQRKKKDIKLSTQFLSCSTAVSEKALLSSYLVAYRVAKEKIANTAAEKIILPACLDMVRTIFDDKSADKLKTIPNDNTVSLRICTIAEHLETMLITRLQSGIDFAIQLDESTDIGSCTTLLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSDGTATMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLMEVLKNAVKVVNFIKGSSLNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRNEIHFFLIEKKSHLASIFEDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSNRPSYYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENSWVKDPFAFRHPESIIELNLVPEEENELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSCVPDWNELMNRQAHPS
What are the official names of this protein?
Protein FAM200B.
What is the protein family that this protein belongs to?
Belongs to the FAM200 family.
Protein: MTGA_MANSM
Sequence: MRLKTLKFPFVNKKNTRTFKKKCGRFLSYFIGLTVALTFLFRFVPIPFSAYMAEQKLAHIIQLDFDYKVNYDWISLEDISPYMQLAVIAAEDQNFPNHGGFDWNAIKSAIKYNEKSSRIRGASTISQQTAKNMFLWHGQSWIRKGIEVPVTFMLETLWSKKRILEVYLNIAEFGNGIFGVEAASRYYFKKPAKRLTQSEAALLAAVLPNPIIYKANRPSLLVRKKQAWIIRQMNSLGLNYLKKL
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.