PharMolix/UniProtQA huggingface dataset:
Protein: NNRD_CAEEL
Sequence: MDHFIKLLPKLTPHLRKGDCGKMGVIGGSLEYTGAPYFAASSASRLGADLIHIFCDPDAAQVIKGYSPDLIVHPGMTANSIIPKLSRMDAIVIGPGLGRNPNIWPLMQELFEFVRNRDVPFVIDGDGLWFVSEHIEKFPRQMSATVLTPNIVEFSRLCKSALGEEDVLNVRNNSQLQHLAAELSRKMNVTIYLKGEVDLVVTPNGEVSKCSTESSLRRCGGQGDVTAGSLGLFLYWAKKNLGDDWTSAHHEAGIASSWLVRTAGRRAFEKHGRSMNTPLLLDEIPKLVRDVETREMKDTVHTDSSKH
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
Protein: RPOB_PROM1
Sequence: MSRSAIQVAKAATYLPDLVEVQRSSFKWFLDKGLIEELDNFSPITDYTGKLELHFIGAEYKLKRPRHDVEEAKRRDATFASQMYVTCRLVNKETGEIKEQEVFIGELPLMTERGTFIINGAERVIVNQIVRSPGVYFKDEQDKNGRRTYNASVIPNRGAWLKFETDKNDLLHVRVDKTRKINAHVLMRAMGLSDNDVIDKLRHPEFYKKSIDAANEEGISSEDQALLELYKKLRPGEPPSVSGGQQLLQTRFFDPKRYDLGRVGRYKINKKLRLTIPDNLRTLTNEDVLSTLDYLINLELDVGGATLDDIDHLGNRRVRSVGELLQNQVRVGLNRLERIIKERMTVGETDSLTPAQLVNPKPLVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRISALGPGGLTRERAGFAVRDIHPSHYGRLCPIETPEGPNAGLINSLATHARVNEYGFIETPFWKVENGRLIKEGDPIYLSADLEDECRVAPGDVATNEEGKIMAELVPVRYRQDFETVSPEQVDYVQLSPVQVISVAASLIPFLEHDDANRALMGSNMQRQAVPLLRPERPLVGTGLETQVARDSGMVPISKVNGTVSYVDANAIVVTDDEGNDHTHYLQKYQRSNQDTCLNHRPIVFNGDPVIVGQVLADGSACEGGEIALGQNVLIAYMPWEGYNYEDAILVSERLVKDDLYTSVHIEKYEIEARQTKLGPEEITREIPNVSEENLGNLDEMGIIRIGAYVESGDILVGKVTPKGESDQPPEEKLLRAIFGEKARDVRDNSLRVPSTERGRVVDVRIYTREQGDELPPGANMVVRVYVAQRRKIQVGDKMAGRHGNKGIISRILPREDMPYLPDGTPVDICLNPLGVPSRMNVGQVFELLMGWAASNLDCRVKIVPFDEMYGPEMSNQTVQAYLKEAAKQPGKSWVYNPKDPGKLLLKDGRTGEPFDQPVAVGYAHFLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRLGEMEVWALEAYGAAYTLQELLTVKSDDMQGRNEALNSIVKGKPIPRPGTPESFKVLMRELQSLGLDIGVYTDDGKEVDLMQDVNPRRSTPSRPTYESLGKEYEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: GATA_BORGP
Sequence: MDLSNLTLTKIQELVLTKKCKIYDILLAYKNNYELNKDINGYIEFFDDSLDIAKRYDDCLKNCELEDLPLIGMPIAVKDNISIQDKSLTCASEILKGYISPYDATVIKRLKNKGAILIGKTNMDEFAMGSTGEFSCYGATLNPLNREYVIGGSSGGSAAVVASFQAPFSLGSDTGGSVRLPASFSGILGFKPSYGGLSRYGLASYASSFDQIGFFSHSIEDIALILKHTCGADKMDSTSVDIFDDFYPLKTEPLQGKNLALIKELSEDLMDKNVASSFAKFKFDLLSKGANIKEVSIEEINFILSIYYTISPVEASSNLARYTGLCYGKRISENLSLNDFYFKHRSNFLSEEVKRRIILGNYLLSEGYDAKYYAKACEILQNLIIPKFNKLFESCDFIITPTSFVKPFRVGLDFDDPVKMYYSDICTVIANLIGAPAISLPYSKDKEGLSIGMQIIGRSKKDFELLSFSKNVIRELGLNGI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: HOX3_BRAFL
Sequence: MQKSPYYETTSQQLYNGYSYSNGERFGYEGSGGGGGGGSYGAEVTQDFGPSCSVRKPGSTTGGGTGNVSPTCMKTNPADNNHGSAPQSNASILANTKIYPWMKESRQNSKQRQQPNLSVGTTEPGESPGLGGAAGKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMAAMLNLTERQIKIWFQNRRMKYKKEQKVKGGGSGGGSGGMNSPSPPATTTPPGINPGPLPHPTTQPSLSQSNNMSNHMSMMGSLQQTQPAYSQYPPPHLNHSLPHQAPPHSVGLTMSGPVSPQCYQSNHSPCPPSSAPHPVPMGNHVPHPRQGPPHMTNGLPASPLEVVSQRQYTPPAPGPSPTGPGPGHHGLTNSYPECPPHHTELPHHQYSTPMSVVNMNYCVNVQTQGNRLNSAPKLTHL
What are the official names of this protein?
Homeobox protein HOX3.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AIM32_LACTC
Sequence: MFRVRAPWLKTLVELRQGTTQRRALHSKYRHVGFGASAQLQQSCECFIQKLNRELPRDAQLDASIDLPKKTPSYHKHLMLISPPDEAGKDPEWKGSWQAKLELNPEWPYSAIAEVKKHLKETKRGEGILINAISVMRSKSLGDPSSEKKARFLALPDMKVYEVSQSELKDFAYFVGEGMVQQPRGRAVAFADYLKGADAISKELEHREVASTAAAGMKQFAAQSYQNNLVLVCGHHQRDERCGQIAPRLIKEFEAKVEEDLDLAIVSHIGGHKFAGNVIFYKFLGFEADGKATVDSLWFGKILPSAVPTLLEHLGRNEIITPWFRGGCLLES
What are the official names of this protein?
Altered inheritance of mitochondria protein 32.
What is the protein family that this protein belongs to?
Belongs to the AIM32 family.
Protein: RLMH_METMP
Sequence: MNVTIISVGKIKEKYLSDAIIEYSKRISRYSKLDIIEVADEKTPENPSDVEKSKILEKEAERILKYLKKDSFLITLEILGKELTSEDLAKKINDLSISGKSDITFVIGGSLGLSKNISEISDFKLSFSKMTFPHQLMRVILLEQIYRSFRIISGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Putative ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_PARDP
Sequence: MSMNDPLGDMLTRIRNAQMRGKSTVRTPGSKLRAWVLDVLKAEGYIRGYEEVTTEAGHKELEISLKYYEGTPVIRELARVSKPGRRVYAGAKELPQVRNGLGVSIVSTPKGVMSDAAARSANVGGEVLCTVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: UCRI_SYNEL
Sequence: MAQVSGMSDVPDMGRRQFMNLLTFGTITGTALGALYPVVKYFIPPASGGTGGGAVAKDALGNDIKVSEYLAKHLPGDRSLAQGIKGDPTYVIVTEDHQIANYGLNAVCTHLGCVVPWNVSENKFICPCHGSQYDSTGKVVRGPAPLSLALVKATVTEDDKLVFTPWTEIDFRTGKEPWWT
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, ISP, RISP, Rieske iron-sulfur protein.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: PSBL_PROMP
Sequence: MQVNENPNKVPVELNRTSLYLGLLSVLVLGILFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: SNF7_CRYNB
Sequence: MSGWMSYFTGRKDTRESARDAIVGLRQQLLMLEKKEEFLQKKIEEEMKKAKANATGNKRLAMAALRQKKAHENELDRIAGTRLTLETQVNAIESANLNAETMVAMKKGADALKGIHSNLTAEGVDATMDKIREQMDLTNDISDAISNPVGMGIVLDEDDLKEELEALEQEQLDDRLAGADRVPSHLPASPVGQTTGRAAVEEDEDDEEAQLRKLQAELAM
What is the function of this protein?
Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB).  Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity).
What are the official names of this protein?
Vacuolar-sorting protein SNF7, Vacuolar protein-sorting-associated protein 32.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: EX53_MYCGE
Sequence: MKKAILIDGNSLAYRAYFATWKQVEYAKQNNLPFNNAIRTMLLMCWNLIKANVYQYGIVSFDTKAPTFRDQIYEGYKQKRVKTPVELLVQIPLIKQALVYLGFLVCEKDGFEADDLIGSYANLFTKQEITVDIYSSDRDMLQLVNAFTNVFLCIKGTKEMVMYNNENFKSLFYGLAPYQVVEYKGLVGDNSDNLAGIKGIGPIKGIELLQQYGTIDNIYTNFNNLPNQLQKLLNNQKEIAKTFSFLAKIKTDIELDQNIDLTGLKPIQKQALIQLLSENKINTLVEKFSKI
What is the function of this protein?
5'-3' exonuclease acting preferentially on double-stranded DNA.
What are the official names of this protein?
5'-3' exonuclease.
Protein: PDC1_KLUMA
Sequence: MSEITLGRYLFERLKQVEVQTIFGLPGDFNLSLLDKIYEVPGMRWAGNANELNAAYAADGYARLKGMACVITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISSQAKQLLLHHTLGNGDFTVFHRMSSNISETTAMITDINSAPSEIDRCIRTTYISQRPVYLGLPANLVDLKVPASLLETPIDLSLKPNDPEAENEVLETVLELIKDAKNPVILADACCSRHNVKAETKKLIDITQFPAFVTPMGKGSIDEQHPRFGGVYVGTLSSPEVKEAVESADLVLSVGALLSDFNTGSFSYSYKTKNIVEFHSDYIKVRNATFPGVQMKFVLQKLLTKVKDAAKGYKPVPVPHAPRDNKPVADSTPLKQEWVWTQVGKFLQEGDVVLTETGTSAFGINQTHFPNDTYGISQVLWGSIGFTGGATLGAAFAAEEIDPKKRVILFIGDGSLQLTVQEISTMIRWGLKPYLFVLNNDGYTIERLIHGETAQYNCIQSWKHLDLLPTFGAKDYEAVRVATTGEWNKLTTDKKFQENSKIRLIEVMLPVMDAPSNLVKQAQLTASINAKQE
What are the official names of this protein?
Pyruvate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: KTHY_NAUPA
Sequence: MYIALEGIDTAGKSTQIELLKNEYKNNILFIKEPGFTKFGTKIREIIFNDDISKKAELFLFLADRAETIEKFVKPNLHKNILTDRSVISGIAYAMEFFDFNMLVNLNKFATDGIFPEFVIILKLDKETLQYRLSQKNHDNIEKRGLDYLINIQDNMIEVCNRLEIPYLLLDASKNIEEINFRIKKVISEYMDID
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: FLO6_ORYSJ
Sequence: MLPLLLPLPVTPPPPLPSPTLTLAPASAPRRRLVLLAAAAPHHHHHHRRRRVYRRQRAAPTQTRAPRRTLSASNAARGEEDLEEAIYEFMRRSDKPGAFPTRAELVAAGRADLAAAVDACGGWLSLGWSSGGAEAGRASSSVGVHPDYPPEAGAAAAAGGASDLAQGAVWASSREAEASPSGRQPETEEEETETKFGTGLDGMLTRLQRERERVRPPLPRSSDGAGGERDNVALMGQSGAPSHSATGGRYTPKVPDNGNIHSYHPQNGALEHNKSSKSLTNDAWRTWSLDKGGFSDFQAAEIHSTNSRKSFRHDGLDILAQDDVHGPSNGVAVHDYDINDVDSERDDIHARLQNLELDLTAALHTLRSRFDKVISDMSEGDGAKAPNGLSDDWEFEETKVMQAQEELRSIRAKIAVLEGKMALEIIEKNKIIEEKQRRLDEAEKALSELRTVYIVWSNPASEVLLTGSFDGWTSQRRMERSERGTFSLNLRLYPGRYEIKFIVDGVWRNDPLRPLVSNNGHENNLLTVT
What is the function of this protein?
Involved in compound starch granule formation and starch synthesis in endosperm.  May act as a regulatory scaffolding protein and affect starch synthesis and compound starch granule formation through direct interaction with isoamylase 1 (ISA1).  Binds starch, amylopectin and amylose through its C-terminal carbohydrate-binding domain (CBM) in vitro.
What are the official names of this protein?
Protein FLOURY ENDOSPERM 6, chloroplastic, SKIPa-interacting protein 4.
What are the subcellular locations of this protein?
Plastid, chloroplast. Note=Localizes to granule-like structures in chloroplasts.
Protein: THIG_HYDCU
Sequence: MNLTPEHAQKSSPMSWTVGGKTLNSRLLIGSALYPSPQAMQGAIEASGAEIVTVSLRRQSAGDQAGKTFWNMIKSLNCHVLPNTAGCHSAKEAITTAQMAREVFETNWIKLEVIGDQYNLQPDPFELLKATETLVNDGFEVFPYTTDDLVLAQRLVEAGCNILMPWGSPIGSGKGLMNPYNLNAIRQRFPELTLIVDAGIGKPSHAVQALEMGYNGILLNSAVALSPNPITMGKAFKSAVEAGVYAFDAGTMQERDLASPSTPVVGTPFWHQH
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_VARPS
Sequence: MTTASAIPDNDPLVLYGQTFHSRLLLGTARYPSPDLLEAAVKRAKPAMLTASLRRQSASPGASDSGNGFWELLRRLAVPVLPNTAGCHSVQEVIATAQMARELFDTPWIKLELIGDDYTLQPDTLNLVDAASQLIRDGFQVLPYCTEDLVLCQRLVDVGCQAVMPWAAPIGTGRGPVNPYALQLLRERLSVPMLVDAGLGLPSHACQVMEWGYDGVLLNTAVALAQDPVSMAGAFADAVQAGRAAHRAGAMAAQDSAQPSTPVLGTPFWHHAP
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KA20_TITSE
Sequence: MHSSVFILILFSLAVINPIFFDMKVEAGCMKEYCAGQCRGKVSQDYCLKHCKCIPRFI
What is the function of this protein?
Blocks potassium channels.
What are the official names of this protein?
Potassium channel toxin Ts16, Tityustoxin-16.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 20 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_ECOSE
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: CYSH_ZYMMO
Sequence: MSAFHLETLKSLPKAEQEAALSEANRQLEEMSAEDRLKWAFDNLSGQFVLSSSFGIQAAVMLHLVTRKKADIPVILTDTGYLFPETYRFIDALTEKLDLNLQVFRAALSPAWQEARYGKLWEQGVEGIERYNDINKVEPMNRALKTLEAGTWFAGLRRDQSKSRSHLPILAIQRGVFKFLPIIDWDNRKIHYYLKEHDLPYHPLWDEGYLSVGDTHTTRKWEEGMSEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_DROPS
Sequence: MRRHLQWSIKQLTSSYADGQLSPRRVTEQALEDSVNLKTLNAFVRLTPEEARQQAQQSEQRYQKKQPSSGLDGVTIAIKDNFCTENVHTTCASRMLQDFVPPYDATVCSRLRQAGAVLLGKTNMDQFAMGAGTVDSIYGPTKNIWSEDLTQNNWRIAGGSSGGSASAVAAGLCFAGIGSDTGGSTRNPASYCGVVGLKPTYGLVSRHGLIPLVNSMDVPGILARSVSDCVEVLNAVAGPDGKDSTTIRQPFTKLQLPEVDGLDLQTVRIGIPKEYHCNGLSAEVLETWTKVADLLECAGASVQQVSLPNTAASIFVYSILNQCEVASNMARYDGIEFGHRAADERSTEQLYAQSRAEGFNDVVKTRILTGNFLLLRKNYDHYFEKALRVRRLIAEDFLKVFEAPSKEDRVDILLTPTTLTEAPLYKDFSSLSNRDQCAVQDFCTQPANMAGIPAVSIPIRLSRSGLPLSLQLMSRSLNEQLLLSVARWIEAQVAFDSLDHRLEQKLS
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CAIA_ECO45
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_STACT
Sequence: MNKIQESFLYMLKVERFFSKHTLKSYHDDLVQFNAFLEHEHLKLKSFEYKDARNYLSFLYSKGLKRTTVSRKISTLRSFYEFWMTQDDTVVNPFVQLVHPKKEQYLPHFFYEEEMSALFETVEADGHKGLRDRVILELLYGTGIRVSELVNIKLEDLDLNSPGVKVLGKGNKERFIPFGNMCRESIERYLELFPPIQNVKHDYLLVNINGRPITERGVRYVLNDIVKRTAGVTDIHPHKLRHTFATHMLNEGADLRTVQSLLGHVNLSTTGRYTHVSNQQLRKVYLNAHPRAKKEK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_SYNP6
Sequence: MTETNFDFLAQGDPAIAAIIGRELQRQQEHLELIASENFASPAVMAAQGSVLTNKYAEGLPSKRYYGGCEFVDQAEELAIERAKELFGAAHANVQPHSGAQANFAVFLTLLQPGDTFLGMDLSHGGHLTHGSPVNVSGKWFNAGHYGVNRETERLDYDAIRELALQHRPKLIICGYSAYPRTIDFAKFREIADEVGAYLLADMAHIAGLVAAGLHPSPIPHCDVVTTTTHKTLRGPRGGLILTRDAELGKKLDKSVFPGTQGGPLEHVIAAKAVAFGEALRPEFKTYSAQVIANAQALARQLQARGLKIVSDGTDNHLLLVDLRSIGMTGKVADLLVSDVNITANKNTVPFDPESPFVTSGIRLGTAAMTTRGFKEAEFAIVADIIADRLLNPEDSSMEDSCRRRVLELCQRFPLYPHLSPATPVAV
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_COXB2
Sequence: MKFVDEAFVRVEAGNGGHGCLSFRREKFIPRGGPDGGDGGDGGSVYFVADKSVNTLVEFRYQRLLRAQNGQPGMGRLRSGKKGEDLIVPVPLGTTVYDKETSELIGDLIEAGDKLCVARGGRHGLGNTHFKSSTNRAPRRTTSGEEGEARELKLELKLLADVGLLGLPNAGKSTFIHAVSKATPKIADYPFTTLYPHLGVVRVEEYRSFVIADIPGLIEGASEGAGLGVQFLKHLERTQLLLHIVDIAPLDGSDPVQSIQAIISELEQFSQNLSQKPRWLVFNKIDLLPPDVAQARCQEIINRLNWKGPVYKISAIKRQGTELLCYDLMSFLETNQRSI
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP6_ROTPC
Sequence: MDVLFSIAKTVSDLKKKVVVGTIYTNVEDIIQQTNELIRTLNGNTFHTGGIGTQPQKEWNFQLPQLGTTLLNLDDNYVQATRSVIDYLASFIEAVCDDEIVREASRNGMQPQSPTLIALASSKFKTINFNNSSQSIKNWSAQSRRENPVYEYKNPMVFEYRNSYILQRANPQYGNVMGLRYYTASNTCQLAAFDSTLAENAPNNTQRFIYNGRLKRPISNVLMKIEAGAPNINNLTILPDPTNQTTWLYNPDQLMNGTFTIEFYNNGQLVDMVRNMGVVTVRTFDSYRITIDMIRPAAMTQYVQRLFPQGGPYPYQAAYMLTLSILDATTESVLCDSHSVDYSIVANVRRDSAMPAGTVFQPGFPWEQTLSNYTVAQEDNLERLLLVASVKRMVM
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RNC_ECO5E
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_METMJ
Sequence: MSGKPLLVTCGLPYTNGPCHIGHLRTYVPADFYVRYMRRSGEEVVFVCGSDNHGTPIVISAEQEGSTPRVLSERYHEHFYETFRRMDVVFDRFGMTDDAMNHETTRSIVERLIENGYVYAETVSQSYCPDCERFLPDRYVEGICPHCGAVARGDECDQGCGQHLEPGEIKDAICKVCGGKAEYREQEHYFFRLSAFREFLLDYLPALGGTSTARNYALGWVKELLHDWCITRTLDWGVKFPGRDDLVVYVWVDAPIGYISFTKEWAQKAGADWKDYWCGDETGVTHFIGGDIIYHHCIFWPALLKGAGYGLPSAVVASGMVTIEGKKFSKSRGYVVWTNDDYLDQGLPADYLRYYLLSYTNHTKELDFSWKVYGERVNNEIVGTLGNFIYRTMYFAEKEFSGVPDLAPRLEVIEEIERSLAAVDGLMRDYDFKNAVDAMMTLASFGNGYIQNNAPWKLIKEDRAAAEQVIADCLQIVKALVLVFEPLMPDAMQRAWTMLGYGDDIADHAIAEATAPVGARPLAKPSTLFAKVEKDQVAALEATLNERVERANAAAAPKMPVVSIEEFGNLDIRIAKVVSAEPIKGSKKLYKLVVDLGSEKRQVVSGIAQFYAPDELVGKDVALIANLAPAKIFGVESRGMILAAGDEASLLVPLRPVKPGTKIR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.