PharMolix/UniProtQA huggingface dataset:
Protein: NRAM_I71A2
Sequence: MNPNQKIITIGVVNTTLSTIALLIGVGNLVFNTVIHEKIGNHQTVIHPTITTPAVPNCSDTIITYNNTVINNITTTIITEAERLFKPPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYAGRMTDSIKSWRKDILRTQESECQCIGGTCVVAVTDGPAANSADHRVYWIREGRIVKYENVPKTKIQHLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTVSCDSPSNINGGPGVKGFGFKAGNDVWLGRTVSTSGRSGFEIIKVTDGWINSPNHAKSVTQTLVSNNDWSGYSGSFIVKTKGCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: GLPK_AGARV
Sequence: MAKYIMALDAGTTSNRCILFNEKGEMCSVAQKEFTQFFPKPGWVEHDAEEIWATQLEVAKEAMANIQATAADICAIGITNQRETTIVWDKNTGEPVYHAIVWQCRRTAEYADSLKEKGLTETFRKKTGLVIDAYFSATKLKWLLDNVPGARERAERGELLFGTVETWLIWKLTQGQVHVTDYSNASRTMMFNINTLKWDDEILKELDIPKSMLPKPMPSSCVYGEVNPVYFGGPIPIAGAAGDQQAALFGQTCFRAGEAKNTYGTGCFLLMNTGEMPVSSKNGLVTTIAWGIDGKVVYALEGSIFVAGASIQWLRDEMKFIDSSTDSEYMARKVKDTNGCYVVPAFTGLGAPYWDQYARGTIVGLTRGVNKYHVIRATLESMAFQVNDVLEAMKADSGINLTSLKVDGGASANNLLMQMQADISNAPVNRPVCVETTAMGAAYLAGLAVGYWDSMDDIKRNWAIDRVFEPEIADDMREKKRKMWKKAVACAFNWAKDD
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: SSAA2_STAAS
Sequence: MKKIATATIATAGFATIAIASGNQAHASEQDNYGYNPNDPTSYSYTYTIDAQGNYHYTWKGNWHPSQLNQDNGYYSYYYYNGYNNYNYNNYNNGYSYNNYSRYNNYSNNNQSYNYNNYNSYNTNSYRTGGLGASYSTSSNNVQVTTTMAPSSNGRSISSGYTSGRNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAARAGYTVNNTPKAGAIMQTTQGAYGHVAYVESVNSNGSVRVSEMNYGYGPGVVTSRTISASQAAGYNFIH
What is the function of this protein?
Not known; immunogenic protein.
What are the official names of this protein?
Staphylococcal secretory antigen ssaA2.
What are the subcellular locations of this protein?
Secreted.
Protein: KBX3_HOFGE
Sequence: MNTKLTVLCFLGIVTIVSCGWMSEKKVQGILDKKLPEGIIRNAAKAIVHKMAKNQFGCFANVDVKGDCKRHCKAEDKEGICHGTKCKCGVPISYL
What is the function of this protein?
Blocks Kv1. 1/KCNA1 (IC(50)=185 nM) potassium channels.  Shows a weak hemolytic activity.
What are the official names of this protein?
Hge-scorpine, Hg-scorpine-like 1, HgeScplp1, Hgscplike1.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 3 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAZ_THISH
Sequence: MFRGVANLNLDTKGRMAMPSRYRDRLVETCEGRLVITVDRDGCLLVYPQPEWERIEQALMSRPNMDRQVRRLQRLLVGHATECELDGQGRILLPPPLRDYAGLDKRVVLVGQGNKFELWDEDTWVKSRDEWFKEEDETAEPSAVLESLSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: 3NB3_TRIBI
Sequence: MKTLLLALVVVAFMCLGSADEVGLGNEQIDRGRRQAIGPPFTRCSKCNRNWSPPFPLGLYTVSHVKSCGGHLSSIGQCGEDWVVKGCAKTCPTAGPGERVKCCYSPRCNKN
What is the function of this protein?
Potent postsynaptic neurotoxin.  Displays readily reversible competitive antagonism at the nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Toxin 3FTx-Tri3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Boigatoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYL_CHLPN
Sequence: MRYDPNLIEKKWQQFWKEHRSFQANEDEDKVKYYVLDMFPYPSGAGLHVGHLIGYTATDIVARYKRARGFSVLHPMGWDSFGLPAEQYAIRTGTHPKVTTQKNIANFKKQLSAMGFSYDEGREFATSDPDYYHWTQKLFLFLYDQGLAYMADMAVNYCPELGTVLSNEEVENGFSIEGGYPVERKMLRQWILKITAYADKLLEGLDALDWPENVKQLQKNWIGKSEGALVTFHLTQEGSLEAFTTRLDTLLGVSFLVIAPEHPDLDSIVSEEQRDEVTAYVQESLRKSERDRISSVKTKTGVFTGNYAKHPITGNLLPVWISDYVVLGYGTGVVMGVPAHDERDREFAEMFSLPIHEVIDDNGVCIHSNYNDFCLNGLSGQEAKDYVINYLEMRSLGRAKTMYRLRDWLFSRQRYWGEPIPIIHFEDGTHRPLEDDELPLLPPNIDDYRPEGFGQGPLAKAQDWVHIYDEKTGRPGCRETYTMPQWAGSCWYYLRFCDAHNSQLPWSKEKESYWMPVDLYIGGAEHAVLHLLYSRFWHRVFYDAGLVSTPEPFKKLINQGLVLASSYRIPGKGYVSIEDVREENGTWISTCGEIVEVRQEKMSKSKLNGVDPQVLIEEYGADALRMYAMFSGPLDKNKTWSNEGVGGCRRFLNRFYDLVTSSEVQDIEDRDGLVLAHKLVFRITEHIEKMSLNTIPSSFMEFLNDFSKLPVYSKRALSMAVRVLEPIAPHISEELWVILGNPPGIDQAAWPQIDESYLVAQTVTFVVQVNGKLRGRLEVAKEAPKEEVLSLSRSVVAKYLENAQIRKEIYVPNKLVNFVL
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP2A2_ORYSJ
Sequence: MSSPHGGLDDQIERLMQCKPLPEPEVRALCEKAKEILMEESNVQPVKSPVTICGDIHGQFHDLAELFRIGGKCPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPQRITILRGNHESRQITQVYGFYDECLRKYGNANVWKTFTDLFDYFPLTALVESEIFCLHGGLSPSIETLDNIRNFDRVQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEQFNHTNNLRLIARAHQLVMEGFNWAHEQKVVTIFSAPNYCYRCGNMASILEVDDCREHTFIQFEPAPRRGEPDVTRRTPDYFL
What are the official names of this protein?
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGRP_BOVIN
Sequence: MLTAVLLSCALLLAMPPLQGAQMGPAPLEGIGRPEEALFLELQGLSLQPSLKRITEEQAEESLLQEAEAKALAEVLDPEGRKPRSPRRCVRLHESCLGHQVPCCDPCATCYCRFFNAFCYCRKLGTTTNPCSRT
What is the function of this protein?
Plays a role in weight homeostasis.  Involved in the control of feeding behavior through the central melanocortin system.  Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland.  Has very low activity with MC5R.  Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity.  It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
What are the official names of this protein?
Agouti-related protein.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus lumen.
Protein: PURA_SALEP
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPSALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKVEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEYGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UGPC_RALSO
Sequence: MAKLSLRNVQKHYAGLQVVHGIDMEIGDGEFIVIVGPSGCGKSTLLRMVAGLEAITGGEVWIGDRVVNELEPAERDIAMVFQNYALYPHMTVFDNMAYGLKIRGLPKSEILARVQQAAGILELGKLLERKPRQLSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVQMRLELKELHRRLRTTSLYVTHDQVEAMTLADRMMVLSGGRVEQIGTPLEVYARPASTFVAGFIGSPPMNLVPVSRHAGEGAQIRVDGAQAGDAPATLGHLPMGLHLPEHALMGLRPEHIEPCAADRAIAFVEVRLVEALGADAFAYGALAGHPVVVRLDPHASVKAGDRLPITASADHLHWFDPQTTRRIEALA
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TXI1A_ETHRU
Sequence: MQRFLCLVACSVVLLVLGIVADDEIGQVPEGGWTRGNKSNGERCKFNQHCHSKCCVLSERGKPRVCASKALEGESCNAGQIKGGYHARFCPCALGNGKCIKNICQLL
What are the official names of this protein?
U-scoloptoxin(18)-Er1a, U-SLPTX(18)-Er1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-18 family.
What are the subcellular locations of this protein?
Secreted.
Protein: QCR1_RAT
Sequence: MAASAVCRAACSGTQALLRTCRSPALLRLPALRGTATFVQALQSVPETQVSVLDNGLRVASEQSSHPTCTVGVWIDVGSRYETEKNNGAGYFLEHLAFKGTKNRPGNALEKEVESIGAHLNAYSTREHTAYLIKALSKDLPKVVELLADIVQNISLEDSQIEKERDVILREMQENDASMQNVVFDYLHATAFQGTPLAQAVEGPSENVRRLSRTDLTDYLSRHYKAPRMVLAAAGGVKHQQLLDLAQDHFSSVSQVYEEDAVPSITPCRFTGSEIRHRDDALPLAHVAIAVEGPGWANPDNVALQVANAIIGHYDCTYGGGVHLSSPLASVAVANKLCQSFQTFNISYSETGLLGAHFVCDAMSIDDMIFFLQGQWMRLCTSATESEVTRGKNILRNALISHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIEEVDAQMVREVCSKYFYDQCPAVAGYGPIEQLSDYNRIRSGMFWLRF
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (By similarity).  The 2 core subunits UQCRC1/QCR1 and UQCRC2/QCR2 are homologous to the 2 mitochondrial-processing peptidase (MPP) subunits beta-MPP and alpha-MPP respectively, and they seem to have preserved their MPP processing properties.  May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS)/subunit 9 when incorporated into complex III (By similarity).  Seems to play an important role in the maintenance of proper mitochondrial function in nigral dopaminergic neurons (By similarity).
What are the official names of this protein?
Cytochrome b-c1 complex subunit 1, mitochondrial, Complex III subunit 1, Core protein I, Ubiquinol-cytochrome-c reductase complex core protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: FDHE_SALA4
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKHWQKLLHSLIAELKPEMSGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAMD8_HUMAN
Sequence: MAGPNQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMGSMTPFISALQSTDWLCNGELSHDCDGPITDLNSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHTCGDYMFSGHTVVLTMLNFFVTEYTPRSWNFLHTLSWVLNLFGIFFILAAHEHYSIDVFIAFYITTRLFLYYHTLANTRAYQQSRRARIWFPMFSFFECNVNGTVPNEYCWPFSKPAIMKRLIG
What is the function of this protein?
Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide.  SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield.  Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides.  Seems to be critical for the integrity of the early secretory pathway.
What are the official names of this protein?
Sphingomyelin synthase-related protein 1, SMSr, Ceramide phosphoethanolamine synthase, CPE synthase, Sterile alpha motif domain-containing protein 8, SAM domain-containing protein 8.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: KDSA_LEPIC
Sequence: MKDNTCTKRDFLNGTKIGGDEPFFLISGPCVMENRDLLDRVCAEMIEVCGELKIPYIFKSSFDKANRSSVNSYRGPGLAEGIKNLEYIKNKYNVPVLTDIHETSQISPLKDVIDVYQIPAFLCRQTDLISQSAQTGKWVNVKKGQFLAPADTRHIAVKMNESGNNKLLVTERGTSFGYGNLIFDGRAIPIIHGFDIPLVFDATHSAQLPGAAGNSTGGQREFIPSILRSAVSFGIEGIFMEVHPDPPNALSDATTQYPLSQIKSLLKEMIGLDRYIKKEILISRSSL
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKH_DROME
Sequence: MNPKSEVLIAAVLFMLLACVQCQLTFSPDWGKRSVGGAGPGTFFETQQGNCKTSNEMLLEIFRFVQSQAQLFLDCKHRE
What is the function of this protein?
Probably causes a marked increase in hemolymph carbohydrate.
What are the official names of this protein?
Adipokinetic hormone, Hypertrehalosaemic hormone, HRTH, dAKH.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14_VIBPA
Sequence: MAKQSMKAREAKRAKLVAKFAEKRAALKAIISDVNASEEDRWNAVLTLQSLPRDSSASRQRNRCNQTGRPHGYLRKFGLSRIKVREACMKGEIPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: VRAR_STAAM
Sequence: MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
What is the function of this protein?
Member of the two-component regulatory system VraS/VraR involved in the control of the cell wall peptidoglycan biosynthesis.  Upon cellular stress, the histidine kinase VraS transfers the phosphoryl group onto VraR (PubMed:18326495).  Upon phosphorylation, VraR dimerizes at the N-terminal domain (PubMed:23650349, PubMed:18326495).  In turn, phosphorylation-induced dimerization expands and enhances the VraR binding to its own promoter leading to increased expression and subsequent modulation of about 40 genes, which ultimately constitute the S. aureus response to cell wall damage (PubMed:10708580).  In addition, inhibits the host autophagic flux and delays the early stage of autophagosome formation, thereby promoting bacterial survival.  Facilitates the ability of S. aureus to resist host polymorphonuclear leukocytes-mediated phagocytosis and killing thus contributing to immune evasion (By similarity).
What are the official names of this protein?
Response regulator protein VraR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLIAC_CANSA
Sequence: MAVKHLIVLKFKDEITEAQKEEFFKTYVNLVNIIPAMKDVYWGKDVTQKNKEEGYTHIVEVTFESVETIQDYIIHPAHVGFGDVYRSFWEKLLIFDYTPRK
What is the function of this protein?
Involved in the biosynthesis of cannabinoids-related terpenophenolic natural products, which have pharmacological activity (PubMed:22802619).  Polyketide cyclase which functions in concert with OLS/TKS to form olivetolic acid (PubMed:22802619, PubMed:26783002).  Has no intrinsic polyketide synthase activity and requires the presence of OLS to produce olivetolic acid (PubMed:22802619).
What are the official names of this protein?
Olivetolic acid cyclase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_CERSK
Sequence: MNEPKLISGNANLTLAKSIARRMSVHRGMAVSLVDARVERFNDQEIFVEVYENVRGEDMYVIQPTSNPANDNLMELLIIADALRRSSADRITAVIPYFGYARQDRRAKARTPISAKLVANLIVEAGIDRVLTLDLHAAQIQGFFDIPVDNLYSAPVFALDIEHHFKGQLQDLMVVSPDVGGVARAREIAKRINAPLAIVDKRREKPGEIAEMTVIGNVAGKKCIIVDDICDTAGTLCKAAEVLIENGAVEVHSYITHGVLSGPAVERVTKSVMKSLVITDSIEPSAAVRGAPNIRIVPTAPMFAQAILNIWSGTSVSSLFETDTLVPIYEGMYQRG
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_THEM4
Sequence: MAVVTMKQLLEAGVHFGHRTQRWNPKMKEYIFGARKGIYIIDLQKTSKLLEEAYNFVRDKAAEGGTILFVGTKKQAQQVIKQEAERCGAFYVNHRWLGGLLTNFQTIRKRIDKLIELEEMEANGEFDNLPKKEQSRLRRILDKLRKNLGGLKEMDRIPDVIYIVDPRKERNAVYEANLLKIPTVSIVDTNCDPDEIDYIIPGNDDAIRAIQLITSKIADAYLEGKEGVSYQEEPQEQKEENSEEIFDIEDEEESEEI
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PYRD_DICNV
Sequence: MNPYPHLRPLLFCLNPEIAHNLTLQILSRAAVFIPRIKAGNPIHLLGHTFPNRLGLAAGLDKNAVAISAFDRLGFGFIEVGTATPRPQSGNPKPRLFRLPEHQAIINCMGFNNDGVVALCQQVAAVKKRTRALIGINIGKNKLTPNERAADDYLIAMSTAYPYADYLAINISSPNTVGLRDLQHGAALCELLQRLKTERDKLSAVYEKTVPLLVKIAPDNEREQLDEMLSIIEDSGIDGIIATNTTLDKTAVTGHRYADEQGGLSGKPLTEKSTKIIAHIRERLPDLPLIASGGVMSADDYYAKLEAGADLVQIYSGLIYHGPQLIKDCLRMPSPQR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YNZD_BACSU
Sequence: MIREHLLKEIEKKRAELLQIVMANGMTSHITIELSQELDHLLIQYQKQRLRAVAGDE
What is the function of this protein?
Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation.
What are the official names of this protein?
Aspartyl-phosphate phosphatase YnzD, Stage 0 sporulation regulatory protein YnzD.
What is the protein family that this protein belongs to?
Belongs to the spo0E family.
Protein: AROB_PROMH
Sequence: MEKITVTLGERSYPITIASGLFHQPETFLPLKKGQQVMIVTNVTLAPLYLDKVTNTLEQQGVLVDSVILPDGEQYKSLTVMNDVFTALLEKNHNRDTTLLALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLATLPPRELSSGLAEVIKYGIILDKDFFIWLENNIDKLIALEPKAMAYCIRRCCELKAQVVAADEKETSGLRALLNLGHTYGHAIEAHMGYGVWLHGEAVAAGMVMAAKTAQDLGQFTQAETQRVIQLLKKANLPVNGPDEMQPEDYLPHMMRDKKVSAGKLHLVLPKGIGQSELRADISREQVYKAITSCINAN
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM1H2_CRORU
Sequence: QNLPQSYIELVVVADHRMFMKYNSDLNTIRTRVHEIVNFINEFYRSLNIRVSLTDLEIWSDQDFITVQSSAKNTLHSFGEWRKSVLLNRKRHDNAQLLTAIVLDDYTLGLAYLNSMCHPRNSVGLIQDHSPINLLMGVTMAHELGHNLGMEHDGKDCLRGASLCIMRPGLTPGRSYEFSDASMRYYQKFLDQYKPQCILNKP
What is the function of this protein?
This protein is a zinc protease from snake venom that induces hemorrhage.
What are the official names of this protein?
Snake venom metalloproteinase HT-2, SVMP, Hemorrhagic metalloproteinase HT-2, Hemorrhagic toxin II, Ruberlysin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMO_BURCH
Sequence: MSQSPKVGFVSLGCPKALVDSEQIITQLRAEGYEISGSYDGADLVVVNTCGFIDEAVQESLDAIGEALTENGKVIVTGCLGAKSSASGSNLIEEVHPKVLAVTGPHAVGEVMQAVHSHLPKPHDPFVDLVPAAGIKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPVAEVMLEAENLFKSGVKELLVISQDTSAYGVDVKYRTGFWNGKPIKTRMTDLVAALGELAAQYGAWVRLHYVYPYPSVDEVIPLMAEGAFKGHVLPYLDVPFQHAHPEVLKRMKRPANAEKVLERVQKWREICPDLTIRSTFIAGFPGETEEQFETLLDFIREAELDRVGCFAYSPVEGATANDLDGALPDEVREERRARFMEVAEEVSANRMQRKVGKTLKVLIDEVSAEGGIGRTAADAPEIDGVVYVEPAAKASKRYKVGDFVSVKITGADGHDLWGEV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.