PharMolix/UniProtQA huggingface dataset:
Protein: TCPA_MACFA
Sequence: MEGPLSVFGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELGKQKIHPTSVISGYRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDTRGQPRYPVNSVNILKAHGRSQMESKLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  The TRiC complex plays a role in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit alpha, TCP-1-alpha, CCT-alpha.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: TMEDA_KLULA
Sequence: MKSFAACVLLLCALFFEQVFAVRFDIPASTKPEQVCIRDFVSEGQLVLIDIETDGSVGDGQQLNLYVRDSNGNEYRRNRDIAGEVRVVFTAPQSTSFDVCFENVAQVNGRSLSRSIELDIESGSEARDWNKIQASEKLKPVEVELRRIEELTDEIVDEFNYLKGREERLRDTNESTNRRVRNFSIAVIVVLVALGAWQVNYMKNFFRAKHII
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi.  Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Endoplasmic reticulum vesicle protein 25.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Recycles between endoplasmic reticulum and Golgi.
Protein: EFTU_NEIGO
Sequence: MAKEKFERSKPHVNVGTIGHVDHGKTTLTAALTTILAKKFGGAAKAYDQIDNAPEEKARGITINTSHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYIIVFMNKCDMVDDAELFQLVEMEIRDLLSSYDFPGDDCPIVQGSALKALEGDAAYEEKIFELATALDRYIPTPERAVDKPFLLPIEDVFSISGRGTVVTGRVERGIIHVGDEIEIVGLKETQKTTCTGVEMFRKLLDEGQAGDNVGVLLRGTKREDVERGQVLAKRGTITPHTKFKAEVYVLSKEEGGPHTPFFANYRPQFYFRTTDVTGTITLEKGVEMVMPGENVTITVELIAPIAMEEGLRFAIREGGRTVGAGVVSSVIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_AERHH
Sequence: MRLNTLSPAAGSKRVKHRPGRGIGSGLGKTGGRGVKGQTSRSGGGKVRNGFEGGQMPLKIRLPKFGFFSRKSLVSAEVRLNEIALVEGDVVDVSTLKQAGVITKNIVFAKVVLSGNIDRAVTVRGLSVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RRF_ECOUT
Sequence: MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDVQKLTDAAIKKIEAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
Protein: DAD1_ARAVE
Sequence: MGSSAFEVLTFFLKDYKANTPQKLKIIDAYLLYILLTGINQFLYCCLVGTFPFNSFLSGFISCVASFVLGVCLRLQVNPQNSSNFCGIPPERAFADFIFAHVVLHLVVMNFIG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1, Defender against apoptotic cell death 1, Defender against cell death 1, AvDAD1, DAD-1.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PSA_MYCLB
Sequence: MSFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSINDEPHFMVMGGTTESIANALKESYAENASLTDALGIAVAALRAGSADAAGSDQPTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSKGSKGAQNPKGARDSKNSKSYGESTD
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_METVS
Sequence: MDLNIKLDKSGELFNESKKYLVGGVNSPVRSFKPFPFFVKSAKSCFLYDEDGNEFIDYCLAYGPMVLGHANEKILNAVKEQMDFGTAYGVPSEKEIILAKEVINRIPCAEMVRFVNSGTEATMGAIRLARGVTKRNKIIKFEGAFHGAHDYVLVKSGSGALTHGAPNSPGIPEDTTKNTLLIPFNDEGAVRKVISENKGEIACIILEPMMGNVGCILPKDGYLKFLREITEENGIILIFDEVITGFRLSKGGAQEYYGVKADIATLGKILGGGFPIGAIAGKKELMEQFSPKGQVYQAGTFNGNPISVTAGIETLKNLNNAFYKETAKKAEILSNYLIETTEKYKIPARVYSVASIFQVYFNDKDILTYDDAKSSDTEKFMKYFYSLLENGVFIPPSQFECCFTSIKHDDFVLEKTMNAIDIAMKKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHAT2_AMAEX
Sequence: MSDINATRLPAWLVDCPCVGDDVNRLLTRGESLC
What is the function of this protein?
Toxin that belongs to the bicyclic heptapeptides called phallotoxins (PubMed:24050899).  Although structurally related to amatoxins, phallotoxins have a different mode of action, which is the stabilization of F-actin (PubMed:24050899).  Phallotoxins are poisonous when administered parenterally, but not orally because of poor absorption (PubMed:24050899).
What are the official names of this protein?
Phallacidin proprotein 2.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: VAT1_HUMAN
Sequence: MSDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPGPEKEN
What is the function of this protein?
Possesses ATPase activity (By similarity).  Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms.  Has no effect on cell proliferation.  Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2).
What are the official names of this protein?
Synaptic vesicle membrane protein VAT-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein. Note=The majority is localized in the cytoplasm and a small amount is associated with mitochondria.
Protein: Y946_METC4
Sequence: MAGHSQFKNIMHRKGRVDAVRSKVFSKLAREITVAAKLGTPDPSMNPRLRAAILAARAENMPKDNIERAIKKAVGGDGENYEEIRYEGYGPGGAALIVEAQTDNRNRTASDVRSAFTKSGGSLAETGAVAFMFDRVGVIAFAPDVADADTMLEAAIEAGADDVRSDTEGHEVICAQDAYGDVSKALEGRFGEPRRTGLIWKAQNTIDVDDETGEKLIRLVEVIEDQDDVQNVYVNFALSEALVEKMGA
What are the official names of this protein?
Probable transcriptional regulatory protein Mchl_0946.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTG_SALCH
Sequence: MSPSDVPINWKRNLTVTWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGLVFSITFLFSAIASPFWGGLADRKGRKIMLLRSALGMAIVMLLMGMAQNIWQFLILRALLGLLGGFILNANALIATQVPRHKSGWALGTLSTGGVSGALLGPLAGGLLADHYGLRPVFFITASVLFICFLLTFFFIRENFLPVSKKEMLHVREVVASLKNPRLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNIAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILIVALIISVLLLIPMSFVQTPWQLALLRFLLGAADGALLPAVQTLLVYNSTNQIAGRIFSYNQSFRDIGNVTGPLMGAAISASYGFRAVFCVTAGVVLFNAIYSWNSLRRRRLAIE
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECR_CAUVN
Sequence: MAASAGPEIERLIALLSKLPGLGPRSGRRAALALLKKRDTLLAPLATAMAEAQAKVRTCGTCGSLDVTDPCAVCADGSRDGRLLCVVEEVGSVWAMERGGSFKGRYHVLGGLLSALDGIGPEALRIGELVGRVADGSVAEVILALPATVDGQTTAHYIADRLAKTNVPVTMLARGVPVGGDLDWLDDGTIAQALRARRPA
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: SYP_NANEQ
Sequence: MVKKSENPKEWYNEIVRKANIIDDAYPVKGMPVYKPYGYKAFKFLMSLLENKLESIGAEPAWFPIVIPYSIFKKESEHIKGFEEEVFWIERAGNDKLEDPLILRPTSETEMYYMFAKWIESYRDLPLIIYMTNTVYRYETKSTKALIRGREVLWNETHSVHRSEEDAREHMAKAKEVYDYIFWDVLYLPYIWVRRPEWDKFPGGEETYAADAIMPDGRFLQVGTIHLLGQKFAIPFEIKFLDYHPFYKKYGDPNIYIKDKNGNEYKVHAPKEFWEELEKGKLTKTYTIKIGDKEYTISSIEEINEKLKEYDFRKYVWQTSYGISMRAFGGALYWLGDDLGLVMPYKIAPIQIVIIPILGKDDTKVIEYSKKVYELIKDKYRVYLDSDDTKTPGYKYYYYDLIGVPLRIDIGLKEVENNSITIVRRDNKKKYTISLNELEKIDQIFKEMEEDLKQKAKSFVNDMVVRVKTFDELKEAIEQNKIAKAPFCMRESCANQIKELLHAEVRGTDINPENAEKERCVYCGEPAKYWVYIGKTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_SHESH
Sequence: MANAKEIKTKIASVKNTQKITSAMEMVAASKMRKAQDRMAASRPYAENMRKVIGHVAQGSLEYKHPYLEVREAKRVGYIVVSTDRGLCGGLNVNLFKKVVADVKSQREQGVEVEFCPIGARSVQFFNSFGGQVSAYASGLGDAPKLADLIGTVRVMLQAYNEGKLDRLYVVFNRFVNTMSQTPVIEQLLPLPKSEVDEVSHHWDYLYEPDPKELLETLLVRYVESQVYQGVVENLASEQAARMVAMKSATDNAGDLISDLQLVYNKARQAAITQELSEIVAGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SMP_YERPE
Sequence: MARAKLKFRLHRTAIVLICLALLVLLMQGASYFSLSHQLARSEQVEELAQTLAKQVAFSLSPIMDSGDDNIDSQKVDAILQQLTQSSRILDASVYQIDGTLVASAGENVKVRDRLALDGKRPGSYFNHQIVEMIAGNSGPSGFLRMTLDTHVLATESKQVDNTTNLLRLMILVALAVGIILARTLLQGRRSRWQQSPYLLTANIPVKEEDESEDDTPEALVGQAETDHKPADK
What are the official names of this protein?
Protein Smp.
What is the protein family that this protein belongs to?
Belongs to the Smp family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CAPSD_FDVS
Sequence: MKSFKWKENTEEKDDEEKTNEKEQNKPKEIDSKTEQEAKQEKVSEADNSVKDQEGITNKNRPEDISYVDDSTIQAKTALTVEAITNIKGHLIESDQKLADERASQYLQTLTNNAVRYTTTFGISEISDEILIPYYHEIDFQGSDKELPSLFSFETFVNEYYGTDLLTYENEKFKTMMCDHPALSRSSEIFKVNAYKISIKWTGETFNPSIGDPSNIGTTSLIKNIAYVGVHNSDNYKDRKLYSRLKMFLELAANCNIILKGCATRPLGIDYELTKVSKKLNGAKILYNDKAHIIYNGIYHPVTPFCDKVNDILKEGDVDIDFGKIFKYGREVVTKINTYDILNKGYAAIDQFTAYLINMGMQRLLDHRMNANSYKDLTQANYPSRVSLHVFDTLLDEFLYVYKPTDQDWEFCLFVIMIDKEVRSLIMAKTKQMMLSRNLFGQSEIGLKLTNLITRRVQGNIAKNAADYFINVMSSGSIESLCNILCSEMYARFSKFNIECSYLETEYLDLFKFLEILLAFIITPRLAWWNSHKFGKHLYDLMSVFCRSELIAYEARYGCFIKFERSAWVKVDKHVSVYGENDLYDGIYFSFLISRTYSAEEIKAFPFISKIYSLIEPLGDYINLDRKTRAKYPFFETTVRGYLPCSIISYTDITTNNPVNTRVNNIGASIIDLSQRYFTHKPTKTSTKEAYDLILDTIGNTANNLGILMHSTVAPMLATLYDTFLFFADGFNKTSPWVVPRKLGYSGYNVYADRNKSDADRATYLIGGRAIVIPRNLDSTNSMIYTYIGIFVHGVVRCDMVTSTGSYITSSHYDPDSISIMPFNGSEITTLALKVVNHSKRINTVFTLFNYLHSKSTDEILSPVRERLSKFWTTSNARALLNEITRIFNCPIERYFTQMNAYDTMHSDPRVYKPTLYSVSSTGNIDSVQPANCAVNKQYEFGDTYLNEMLKVISHVAFDDELPLFRQTEGLVCGYFTSSSNSPDDYFSVDEDTLYFSIDLDEHPEVFTTVGTNGFSIQLQFKKGNDDHAYTNPMSKDIPSIKFLINRIGNLNAHFVQFINRMLSTQRHLIVLRKVVVDYNVITLGSWNDYTPTSSNVFDQFVKDRDLINIKLDFYDTRFIIQNQSNQLLSQYLFESYRNITPLKDFVVMGGIFGNPNRAESKLTDINKDIYCFGDDNDQTTKYFTSKKSKRVV
What are the official names of this protein?
Putative major capsid protein.
What are the subcellular locations of this protein?
Virion.
Protein: ISCS_VESOH
Sequence: MSIPTYMDYSATTPVDERVAQKMIQFLTKDGNFGNSASNSHYYGWQADEAVKKARQQVANLIDADPKEIVWTSGATESNNLAIKGVAHFYHKKGKHIITLKTEHKSVLDTCRQLEREGFEVTYLDPMSNGLLDLNILRDAMREDTILVSIMHVNNEIGVIQDIESIGNLCHQNNIFFHVDAAQSAGKVAISLSELSVDLMSFSAHKIYGPKGMGALYVRRKPRVRIEAQMHGGGHERGMRSGTLATHQIVGMGEAFAIAQAEMREENTKIRQLRDRLLVGFIDMEEVVVNGDMESRIPGNLNISFNYVEGESLMMAINDIAVSSGSACTSLSLEPSYVLRALGLNDELAHSSIRFTIGRYTTEAQIDKAIDLVRAKVDKLRDLSPLWDMFKDGVDISKVEWSAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFB_ALCBS
Sequence: MSGVLIAVAALLALAAVFGAVLGFASEKFKVEGDPIVDQIDSLLPQTQCGQCGHPGCRPYAEAIAEGEEHNRCPPGGQDTVVALSELLGREELTLDDEGAEDANVAKVAYIREDECIGCTKCIQACPVDAIVGAAKLMHTVIVDECTGCDLCVEPCPVDCIDMLEVKPTLQTWGWQRPAGIGERPDSRIEVVNL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: AP3D1_BOVIN
Sequence: MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILRTHPKSVQAHKDLVLQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRRFAVAQMSALLDSAHLVASSPQRSGICEVLYAAAWICGEFSEHLQEPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYAAILQQKEQAADTSAAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAKDVPVAEEVSALFAGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDEKPKAMFQDEEQRHTKPRAPEADEQELARRREARRQEQANNPFYIKSSPSPQKRYQDAPGVEHIPVVQIDLSVPLKVPGMPLSDQYVKLEEERRHRQRLEKDKRKKKKRERERRGTRRHSSLHTESDEDIAPAQRVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPVQKHRNAETSKSPEKEDVPLVEKKSKKPKKKEKKHKEKEREKKKKEVEKGEDLDFWLSTTPPAATPALEELEVNTTVTVLKEGQEEPRGEEQDAEEDREQDLEKKPSKHKKKKHKKDKEERPKDKRKSKKKVPPADEEAAEPVENGTLEEEPLPPMSSYILLAENSYIKMTYDVQGSLQKDSQVTVSVVLENQSDSFLKSMELNVLDSLNARLARPEGSSVHDGVPVPFQLPPGISNEAQFVFTIQSIVMAQKLKGTLSFIAKNDEGSTHEKLDFKLHFTCTSYLVTTPCYSDAFAKLLESGDLSMSSIKVDGISMSFHNLLAKICFHHRFSVVERVDSCASMYSRSIQGHHVCLLVKKGEKSVSVDGKCSDPTLLSNLLEEMKETLATC
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated.  The complex is associated with the Golgi region as well as more peripheral structures.  It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.  Involved in process of CD8+ T-cell and NK cell degranulation.  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
What are the official names of this protein?
AP-3 complex subunit delta-1, AP-3 complex subunit delta, Adaptor-related protein complex 3 subunit delta-1, BLVPCP1, Bovine leukemia virus cell receptor, BLV-R, Delta-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NEC1_HHV2H
Sequence: MYDIAPRRSGSRPGPGRDKTRRRSRFSAAGNPGVERRASRKSLPSHARRLELCLHERRRYRGFFAALAQTPSEEIAIVRSLSVPLVKTTPVSLPFSLDQTVADNCLTLSGMGYYLGIGGCCPACSAGDGRLATVSREALILAFVQQINTIFEHRTFLASLVVLADRHSTPLQDLLADTLGQPELFFVHTILRGGGACDPRFLFYPDPTYGGHMLYVIFPGTSAHLHYRLIDRMLTACPGYRFAAHVWQSTFVLVVRRNAEKPADAEIPTVSAADIYCKMRDISFDGGLMLEYQRLYATFDEFPPP
What is the function of this protein?
Plays an essential role in virion nuclear egress, the first step of virion release from infected cell.  Within the host nucleus, NEC1 interacts with the newly formed capsid through the vertexes and directs it to the inner nuclear membrane by associating with NEC2.  Induces the budding of the capsid at the inner nuclear membrane as well as its envelopment into the perinuclear space.  There, the NEC1/NEC2 complex promotes the fusion of the enveloped capsid with the outer nuclear membrane and the subsequent release of the viral capsid into the cytoplasm where it will reach the secondary budding sites in the host Golgi or trans-Golgi network.
What are the official names of this protein?
Nuclear egress protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae NEC1 protein family.
What are the subcellular locations of this protein?
Host nucleus inner membrane. Note=Remains attached to the nucleus inner membrane through interaction with NEC2.
Protein: UBIG_STUS1
Sequence: MSNVDHAEIAKFEALAHRWWDRESEFKPLHEINPLRVNWIDEHISLAGKKVIDIGCGGGILSEAMAQRGAQVTGIDMGEAPLSVARLHLLESGLEIDYRQITAEAMAAEAPEQFDVVTCLEMLEHVPDPASVIRACATLVKPGGQVFFSTINRNPKAYAFAIIGAEYVLQLLPRGTHDFKKFIRPSELGAWSRDAGLAVKDIIGLTYNPLTKHYKLSADVDVNYMVQTVKES
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: SYC_MESM1
Sequence: MKYIYVCGPTVYNKVHIGNMKPIMTFDLFLRGANFIEKQYLFLHNLTDIDDKIIEKASKENKTELEISELYSDFYLKMLDEYNINKPDYIEKVTDNINMIIEYIGLLVKKGSGYIKKGSVYFDTTKYPEYGSISNLNLNKTLDGDDDFKNEKNNPHDFVLWKKTKVGITWKSPWSEGRPGWHTECSALINHIFKKDQIDIHGGGIDLIFPHNENENIQNIALHGLSLAKKWLHVGHIKWENEKMSKSLNNFILADDFIEKYGNDTFRTLILNTSFSTPISINEEILESNKKISNKYQVTFNQANLLIMQSKKRQNEVETQKYLEKIAKLLENFEFSKINFEINLQIKLFNSVVDLDAANKLVECFKLLGFKFSSQNVSQKDLDLFLKWKIEKTNKNFKISDKLFLELKEKKLV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: PAHO_ANSAN
Sequence: GPSQPTYPGNDAPVEDLRFYYDNLQQYRLNVFRHRY
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions.
What are the official names of this protein?
Pancreatic polypeptide, PP.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: ESTA_SCHGA
Sequence: APIVSGGYDF
What are the official names of this protein?
Esterase 52 kDa subunit, Carboxylic-ester hydrolase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_BORBZ
Sequence: MILSLLSMNINYNSITSIKQTLKERKIAPRKLWGQNYLINESIRQKIIESLDIKENEKIWEIGPGLGAMTEILLKKTNLLTAFEIDLKYSEILNEKFGKLKNFKLIKGDFLKKYKNENQNIDKIFSNLPYNIASKVISKLIEENFLKEMVFTVQKELADRITAKINSKNYSSFTVLVQSHFKVIKILDIGENNFYPAPKVKSTTLKLIPKKNNIKNFKEFNKLVRTVFSNRRKKLKNTIINFITNKATLRENFLKEYLDKRPENISVEEFIQISNTLNAYH
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.