PharMolix/UniProtQA huggingface dataset:
Protein: YDGT_SALTI
Sequence: MTVQDYLLKFRKISSLESLEKLFDHLNYTLTDDMDIVNMYRAADHRRAELVSGGRLFDVGQVPQSVWRYVQ
What is the function of this protein?
Binds to H-NS and modified the range of genes it silences; H-NS alonge silences core gene while the H-NS-Hha complex (and presumably also H-NS-YdgT) silences genes acquired by horizontal gene transfer.  Plays a role silencing virulence factors in the absence of factors that induce pathogenicity (By similarity).  The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC (By similarity).
What are the official names of this protein?
Transcription modulator YdgT, H-NS/StpA-binding protein 2, OriC-binding nucleoid-associated protein.
What is the protein family that this protein belongs to?
Belongs to the Hha/YmoA/Cnu family.
Protein: KEX1_ASPOR
Sequence: MFSSISRGFAKSETGDTFSFSFKSSWLLSLLVLWGPPLTTAKSAADYYVRSLPGAPDGPLLKMHAGHIEVDPQNNGNLFFWHYQNRHIANRQRTVIWLNGGPGCSSMDGALMEVGPYRLKDNLTLEYNEGSWDEFANLLFVDQPVGTGFSYVNTDSYLHELDEMSAHFIIFLDKFFELFPEYEGDDIYLAGESYAGQHIPYIAKAILDRNKNAVSPWNLRGLLIGNGWISPADQYPSYLTFAYEEGLIKEDSRTAKSLEVLQSVCQSKLETGGKDRIHIGDCETVLQELLSKTLDSDNKCYNMYDIRLRDTVPSCGMNWPQDLKDVKPYLRRADVVKALNINPEKKSGWEECSGAVSSSFLPQKSVPAVQLLPSLLESGISVLLFSGDKDLICNHVGTEQLINNMKWGGGVGFETSPGVWAPRHDWTFEGEPAGIYQHARNLTYVLLYNSSHMAPYDLPRQTRDMLDRFMKVDIASIGGSPADSRIDGEKLPQTSVGGHPNSTAAEEQEKERMKQAEWKAYAKSGEAVLVVVIIGVSVWGFFIWRSRQRHRRYQGLYHEDVSGASVLERFHNKRSGQDVEAGDFDESELDDLHSPDMAREHYTVGEDSDEDDVNRQHQRTTINPS
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase kex1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: MRAZ_MYCGI
Sequence: MFFGTYTPKLDDKGRLTLPAKFRDALAGGLMVTKSQDHSLAVHPRAEFEEMIAEISAKAKRGNPQARAYLRNLAASTDEQYPDAQGRITLSPEHRRYANLTKDCVVTGSIDFLEIWDAQAWQEYQELHEENFSAASDEALGDIL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ORN_LEGPC
Sequence: MKNNQNLIWIDLEMTGLEPEQDRIIEMATIVTDPQLNILAEGPVIAVSQPKILLDSMDAWNTKQHNQSGLVKRVLESNVSESQAEQLTIEFLKQYVDKGKSPMCGNSICQDRRFLYKYMPELAAYFHYRNLDVSSLKELVLRWRPELMNGVVKESKHLALDDIKDSINELIYYRQHFINLPEVKNDK
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_LARHH
Sequence: MVVIRLARGGAKNRPFYNIVVTDSRNRRDGRFIERVGFYNPVAAEGSERIRLNSDRLAYWTGVGAQVSDAVAKLLKQQAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL31B_LISMO
Sequence: MKTGIHPEYRPVVFVDTSTDFKFLSGSTKSSSETIKWEDGNEYPLLRVEISSDSHPFYTGKQKHATADGRVDRFNKKYGLK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: NCPR_CATRO
Sequence: MDSSSEKLSPFELMSAILKGAKLDGSNSSDSGVAVSPAVMAMLLENKELVMILTTSVAVLIGCVVVLIWRRSSGSGKKVVEPPKLIVPKSVVEPEEIDEGKKKFTIFFGTQTGTAEGFAKALAEEAKARYEKAVIKVIDIDDYAADDEEYEEKFRKETLAFFILATYGDGEPTDNAARFYKWFVEGNDRGDWLKNLQYGVFGLGNRQYEHFNKIAKVVDEKVAEQGGKRIVPLVLGDDDQCIEDDFAAWRENVWPELDNLLRDEDDTTVSTTYTAAIPEYRVVFPDKSDSLISEANGHANGYANGNTVYDAQHPCRSNVAVRKELHTPASDRSCTHLDFDIAGTGLSYGTGDHVGVYCDNLSETVEEAERLLNLPPETYFSLHADKEDGTPLAGSSLPPPFPPCTLRTALTRYADLLNTPKKSALLALAAYASDPNEADRLKYLASPAGKDEYAQSLVANQRSLLEVMAEFPSAKPPLGVFFAAIAPRLQPRFYSISSSPRMAPSRIHVTCALVYEKTPGGRIHKGVCSTWMKNAIPLEESRDCSWAPIFVRQSNFKLPADPKVPVIMIGPGTGLAPFRGFLQERLALKEEGAELGTAVFFFGCRNRKMDYIYEDELNHFLEIGALSELLVAFSREGPTKQYVQHKMAEKASDIWRMISDGAYVYVCGDAKGMARDVHRTLHTIAQEQGSMDSTQAEGFVKNLQMTGRYLRDVW
What is the function of this protein?
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes.  It can also provide electron transfer to heme oxygenase and cytochrome B5.
What are the official names of this protein?
NADPH--cytochrome P450 reductase, CPR, P450R.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: HIS7_LIMF3
Sequence: MRTATIKRQTKETQIEVSLNLDQQSGIQIDTGVGYFDHMLNLLAKHGRFGLVVKATGDLEVDAHHTVEDTGIVLGETLKEALGDKVQIERYGDAMVPMDETLAQVVVDLSGRSYLVFDAELTNPRLGSFETEVTEDFFQALAFAAEMNLHARVLYGRNTHHKIEALFKATGRALRQAVTINPAIEGVNSTKGVI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDF2_HUMAN
Sequence: MLTRLFSEPGLLSDVPKFASWGDGEDDEPRSDKGDAPPPPPPAPGPGAPGPARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPYPYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDYNSSEYEGPLSPPLCLNGNFSLKQDSSPDHEKSYHYSMHYSALPGSRPTGHGLVFGSSAVRGGVHSENLLSYDMHLHHDRGPMYEELNAFFHN
What is the function of this protein?
Transcriptional regulator implicated in neuronal determination.  Mediates calcium-dependent transcription activation by binding to E box-containing promoter.  Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons.  Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression.  Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex.  Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis.  Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity).
What are the official names of this protein?
Neurogenic differentiation factor 2, NeuroD2, Class A basic helix-loop-helix protein 1, bHLHa1, NeuroD-related factor, NDRF.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAN_AERPE
Sequence: MTLSSAGGSRSHRHNGGHSERDVEIRILKDKVRSLTKEKISLQKELEYYKNEITKLLSPPYIEAVVLEVIDDNRVVVKSSTGPNLIVNVAAGVDARSLKPGAIVALNNRGSTIVDVLPGRYDPLVKAMEVEERPKVFFKDVGGLEEQIREIYEAVVLPIKNPHLFRELGIDPPKGVLLHGPPGTGKTLLAKAVAGETEATFIRVVGSELVNKFIGEGARLVREIFRLAREKAPSILFIDEIDAIASKRVDIGTSGDREVQRTMLQLLAELDGFDPLDNVKVIAATNRLDLIDPAVLRPGRFDRIIEVPLPSLRGRLEILGIHTRKAKMAPDVDLEAIAKLTEGFSGADLKAVVVEAGYNAIRRGSRVITMDDMIKAVEKVKAALDKRGGGDPFIRAQQKSGDDTIATVI
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3695_AGRVS
Sequence: MSDAHGVARDQLRAFVERIERLEEEKKTIADDIKDVYGEAKGMGFDTKILKKVIALRKKDEQERMEEDLILDTYLHALGMIENPPEG
What are the official names of this protein?
UPF0335 protein Avi_3695.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: RS3_NEIG1
Sequence: MGQKINPTGFRLAVTKDWASKWFAKSTDFSTVLKQDIDVRNYLRQKLANASVGRVIIERPAKSARITIHSARPGVVIGKKGEDIEVLKRDLQVLMGVPIHVNIEEIRRPELDAQIIADGIAQQLEKRVQFRRAMKRAMQNAMRSGAKGIKIMTSGRLNGADIARSEWYREGRVPLHTLRANVDYATSEAHTTYGVLGLKVWVYTEGNIKSSKPEHESKQRKAGRRNAAAN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RF3_STAAB
Sequence: MNLKQEVESRKTFAIISHPDAGKTTLTEKLLYFSGAIREAGTVKGKKTGKFATSDWMKVEQERGISVTSSVMQFDYDDYKINILDTPGHEDFSEDTYRTLMAVDSAVMVIDCAKGIEPQTLKLFKVCKMRGIPIFTFINKLDRVGKEPFELLDEIEETLNIETYPMNWPIGMGQSFFGIIDRKSKTIEPFRDEENILHLNDDFELEEDHAITNDSAFEQAIEELMLVEEAGEAFDNDALLSGDLTPVFFGSALANFGVQNFLNAYVDFAPMPNARQTKEEVEVSPFDDSFSGFIFKIQANMDPKHRDRIAFMRVVSGAFERGMDVTLQRTNKKQKITRSTSFMADDKETVNHAVAGDIIGLYDTGNYQIGDTLVGGKQTYSFQDLPQFTPEIFMKVSAKNVMKQKHFHKGIEQLVQEGAIQYYKTLHTNQIILGAVGQLQFEVFEHRMKNEYNVDVVMEPVGRKIARWIENEDQITDKMNTSRSILVKDRYDDLVFLFENEFATRWFEEKFPEIKLYSLL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_HALH5
Sequence: MKPIRIGIGGPVGSGKTHLVEQLTRAMHESYELAVITNDIYTKEDAQFLVKHGILPEDRIIGVETGGCPHTAIREDASMNFEAIHELKQRFTNLDIIFVESGGDNLSATFSPELVDGFIYVIDVAEGQDIPRKGGPGVTRSDLLVINKIDLAPYVEVDLDIMEEDAKQARGERPFVFTDQKRGKGIETIIDWIKRELLLEDMVKEPSV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
Protein: HO_RHOVL
Sequence: MIYDTNLALQLRQGTTKAHSMAENVSFVKSFLGGVVDKQAYRQLIANFYFVYSAIEDEMKRHQESQIIKPIYFEELNRKSSLEEDLQFYYGLEWQDKIFPSPATKVYINRIHEISNTSPELLIAHCYTRYLGDLSGGQILKKITQSAMNLSGGEGTAFYEFKDIKDEKNFKQNYRLALDSIHLSDSAIKSIVSEANIAFKLNMKIFQELNSNFIKIIAIFLFNFIKRIKLPGFKS
What is the function of this protein?
Catalyzes the opening of the heme ring with the release of iron.  Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae.
What are the official names of this protein?
Heme oxygenase.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IF2_PELTS
Sequence: MVKKRVHELAKELKIESKEIINRLNQMGINVKSHMSTLEDGVVERLHQLYRPDQEEVKPAAAKPPAAGQTIKPEEVAPQAQPESRKKDAAMLDSQKPDRDRVQKNGRERAGKATRADHYKGAGLVERVPSRPPDRRFQERPKQSDKARPWGQPRADQGARLKTADFVQERTRSARAGQDYSQPEKVQQERVQDRQQKERPPFEKAQQPRPQHEHKPQDSVKERPHPERASREADNAKRAERLDKGAGKTAEIAYKSGLKALEKAQVGTKPQRAGERGARPGGLHETKPKKNLAPGDAGYAKLWQEQTPVIPQKLLDDRRRQTEEKVKVTEKQKQQAKSQKLVKSREKRNAMAELAEERLRPRPAVAGSRKKGAAKPQEQAQKPAQPLEKKPIVLGESTTVQELALKMHKSPAELIKKLMQLGVMATINQEIDTDTATILAGEFGYEVEVKLPVDIEAMLMQEPEDDPVSLQDRPCVVTVMGHVDHGKTSLLDAIRETNVTATEAGGITQHIGAYQVEHNGKKITFLDTPGHEAFTAMRARGARVTDIAILVVAADDGVMPQTVEAINHAKEAKVPIIVAINKIDKPGANPDRVKQQLTEHGLVAEEWGGDTICVNVSALKKEGLKDLLEMILLVAEMSELKANPNRPARGTVIEAELDKGRGPVANVLVQNGTLNVGDTLIAGAAFGRVRAMMDDKGRRIKKAGPSTPVEVLGFSEVPQAGDIFVVVEDEKLARTIVARRQARKREEELKSTARVSLADLFKHIQEGQIKELGIIIKADVQGSVEALRQALERLSTDEVRVNIIHGGVGAITETDVMLASASNAIIIGFNVRPDVNARKAAENEKVDVRLYRVIYDAIEDVKAAMSGLLEPEYREVTLGRAEIRKIFRSSKIGNIAGCYVLEGKIERDASVRVIRDGIVVHEGKLESLKRFKDDVREVVQGYECGIALEKFNEIQEGDIIEAFTVEAIKRQLT
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_ACIF2
Sequence: MAKKSLIAKSERTPKFKVRAYHRCKLCGRSRGYYRKFGLCRLCFRKHASAGSIPGIVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: UBP50_MOUSE
Sequence: MCFIDMASHRPVPADDFGAYYNLAECADYDSLPESKTQPHFQGVTGLRNLGNTCYMNAILQCLCSVSPLVEYFLSGKYITALKKDCSEVTTAFAYLMTDMWLGDSDCVSPEIFLSAVGSLYPAFLKKTQQDAQEFLIYVLNELHEALKKHCRRRVNEKRTGQSCCRKVPAQETSIITRLFEGQLSYSITCLKCESCTHKNEVFTILSLPIPSDYECSLQDCLQCFFQQDTLTWSNQIYCSFCEIKQEAAVRTTISKVPKIIVFHFKRFDIQGTVKRKLRTDIHYPLTNLDLTPYICPVFRKHPMYNLCAVVNHFGDLDGGHYTAFCKNSVTQAWYSFDDTRVSEIPDTSVQTATAYLLFYSCQPFSIPAQKRKSQDSTPDHCKQAIRKWP
What is the function of this protein?
May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).
What are the official names of this protein?
Putative ubiquitin carboxyl-terminal hydrolase 50, Deubiquitinating enzyme 50, Ubiquitin thioesterase 50, Ubiquitin-specific-processing protease 50.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: TIM50_ARATH
Sequence: MASIVLRSRLLPRLAKLRSRNLRCFSAEASSTNSTSRYSGVTSTQSMFSDFPPPNQPPPPPPPQVEAAAAAATGKERKGLKYLGYALLWALTGATAATGYASFAYTIDEVNEKTKAFRESATKTPVIKSSGIDVIDKYQTKLYSAAMTGSARAIDKYLELREIVEEQVKGFTEPLSEKLLPDLHPAEQHVFTLVLDLNETLLYTDWKRERGWRTFKRPGVDAFLEHLGKFYEIVVYSDQMEMYVLPVCEKLDPNGYIRYKLARGATKYENGKHYRDLSKLNRDPKKILFVSANAFESTLQPENSVPIKPYKLEADDTALVDLIPFLEYVARNSPADIRPVLASFERKDIAKEFIDRSIEYQKRKQGQLGQGRFWRR
What is the function of this protein?
Essential component of the TIM17:23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM50, Protein EMBRYO DEFECTIVE 1860.
What is the protein family that this protein belongs to?
Belongs to the TIM50 family.
Protein: RL32_CAMFF
Sequence: MAVPKRRVSHTRAAKRRTHYKVTLPMPVKDKDGSWKMPHRINKTTGEY
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NIFD_ALCFA
Sequence: MSREEVESLIQEVLEVYPEKARKDRAKHLSPNDPALEQSKKCITSNKKSQPGLMTIRGCAYAGSKGVVWGPIKDMIHISHGPVGCGQSSRAGRGNYYIGTTGVNAFVTMNFTSDFQEKDIVFGGDKKLAKLIDEIETLFPLKKGISVQSECPIGLIGDDIEAVAKKKAAEHETTVVPVRCEGFRGVSQSLGHHIANDAIRDWVLDKRDDDTSFETTPYDVSIIGDYNIGGDAWSSRILLEEMGLRVVATWSGDGTISQMELTPKVKLNLVHCYRSMNYISRHMEEKYGIPLMEYNFFGPTKTAESLRAIAEHFDDSIKAKCEQVIAKYQSEWEAVIAKYRPSLEGKRVMLYVGGLLPRHVIGAYKDLGIELVGTGYGFGHNDDYDRTLKEMGNATLLYDDVTGYEFEEFVKRINPDLIGSGIKEKYIFQKMGIPFRQMHSWDYSGPYHGFDVAIFARNMDMTLNNPCWKKLQAPWEKAEESAEKVAASA
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein alpha chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: FLSO_ASFB7
Sequence: MLHWGPKYWRSLHLYAIFFSDAPSWKEKYEAIQWILNFIESLPCTRCQHHAFSYLTKNPLTLNNSEDFQYWTFAFHNNVNNRLNKKIISWSEYKNIYEQSILKTIEYGKTDFIGAWSSL
What is the function of this protein?
FAD-dependent sulfhydryl oxidase that catalyzes the formation of disulfide bonds in viral proteins produced in the cell cytoplasm (By similarity) (PubMed:16537584).  Involved in virion maturation (PubMed:16537584).
What are the official names of this protein?
FAD-linked sulfhydryl oxidase, p14.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B119L family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: THB_HUMAN
Sequence: MTPNSMTENGLTAWDKPKHCPDREHDWKLVGMSEACLHRKSHSERRSTLKNEQSSPHLIQTTWTSSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
What is the function of this protein?
Nuclear hormone receptor that can act as a repressor or activator of transcription.  High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
What are the official names of this protein?
Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2, c-erbA-2, c-erbA-beta.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIS1_ASPFN
Sequence: MPPLLTNRQAEELHKSMIAYLVASDLPDTAAALRREVNLSEDVFDPTTAKRYEGMLEKKWTSIARLQKKIMDLESRNATLQSELDNSTPASRLKRNQDPASWLPSTVRYSLESHRDKVNCVAFHPTFSSIASGSDDCTIKIWDWELGELERTLKGHTRAVRDVDYGGPRDNVLLASCSSDLSIKLWKPTDNYKNIRTLQGHDHIVSAVRFIPSRNLLVSASRDNDMRIWDVTTGYCVKTINGHTDWVRDVSISFDGRFLFSTGQDMTARLWDISTVSNIEHKRTMLGHENFIECCAFAPPTSYQFLAPLAGLGKRPSSTNGADFMATGSRDNTIKIWDSRGTCLMTLVGHDSWVQALVFHPGGKYLLSVSDDKTLRCWDLNQQGKCVKTLDAHESFVTSLRWAPGVAKNVPGGDGAAEGEGNDKNGAGSENPANIQMRCVVATGGWDQKLKIFAG
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for nuclear migration during vegetative growth as well as development.  Required for retrograde early endosome (EE) transport from the hyphal tip.  Required for localization of dynein to the mitotic spindle poles.  Recruits additional proteins to the dynein complex at SPBs.
What are the official names of this protein?
Nuclear distribution protein nudF, Lissencephaly-1 homolog, LIS-1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.
Protein: H13_CAEEL
Sequence: MSDTVVASAAVQAPAKTVKSPKAAKTTKVPKAKKPVAHPPYINMVTAAINGLKERKGSSKIAILKYITKNYNVGDQIIKINARLRDTLNKGVVSKALVQSVGTGASGRFRVTEKKAAAAKKPVAKKAATGEKKAKKPVAQKAATGEKKAKKTTATKTKKTADKVKKVKSPKKIAKPTAKKVAKSPAKKSAPKKAAAAKPAKKAVAPKT
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1.3, Histone H1-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CGR1_YEAST
Sequence: MVNETGESQKAAKGTPVSGKVWKAEKTPLRAKSRVVKNKKLTSWELKKQKRLEDKQFKERLKALKDEKEEARQAKITMLKERREKKEENERYERLAAKMHAKKVERMRRREKRNKALKER
What is the function of this protein?
Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
What are the official names of this protein?
rRNA-processing protein CGR1, Coiled-coil growth-regulated protein 1.
What is the protein family that this protein belongs to?
Belongs to the CGR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GCSH_PSET1
Sequence: MSNIPSELKYASSHEWVRNEGDGTFTVGITEHAQELLGDMVFVELPEVGDEVDAGEECAVAESVKAASDIYAPIGGEIVAINEELEDAPETVNTDAFGDGWLFRIKASDESELENLLNAEDYANTIDED
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: LEU3_ALIF1
Sequence: MTNKTYKIAVLPGDGIGPEVMEQAHKVLDAIEKKHAISFSREQHDVGGIAIDNHGCPLPESTVKGCEESDAVLFGSVGGPKWEHLPPNDQPERGALLPLRKHFQLFCNLRPAQIHKGLENFSPLRADISERGFDIVVVRELTGGIYFGQPKGREGEGPQEKAYDTEIYHRYEIERIAKIAFESARLRNKNVYSIDKANVLQSSILWREVVEEVAKGYPDVTLNHMYIDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSMGMLPSASLNESNFGLYEPAGGSAPDIAGKNIANPVAQILSAALMLRYSLGEEEAAQSIEAAVSKALSAGELTADLAGDKPALTTSAMGDKIAEYILNS
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_NOSS1
Sequence: METKTAKILDGKTLAEKIQKELTAQIIDAQAKIGRPPGLAVLMVGDNPASAAYVRNKEKSCAKVGIASFGKHFPQETTQTELEDVIAALNQDEQVDGILVQLPLPEHLDAVKLLHQIEPDKDADGLHPVNLGRLVRGEKGLRSCTPAGVMRLLAEYEISLRGKQAVVVGRSILVGKPMALMLLEADATVTIAHSRSQDLKSITQNADILIAAAGLPGLITADMVKPGAVVVDVGINRVSDAHGKSRLVGDINFASIAGVAEYITPVPGGIGPMTVALLLQNTVTSYLQTAKESGALDVK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.