PharMolix/UniProtQA huggingface dataset:
Protein: DDL_BORPA
Sequence: MSKQFGKVGVLYGGRSAEREVSLMSGKGVHEALLSAGVDAHLFDTGERSLADLAAAGFERVFIALHGRYGEDGTLQGALELLGIPYTGSGPLASSLSMDKIMTKRVWLQHGLPTPAFEVLGGSTELRLVPDRLGLPLILKPPHEGSTVGITKVAGYSDMKAAYELAARFDAEVLAEQFITGRELTVAVLGSGAAARALPVIEIVAPGGNYDYEHKYFSDDTQYFCPADLPADVAADVAAVAERAYAALGCEGWGRVDFILDRENRPWLLEMNTSPGMTGHSLVPMAARAVGMSYADLCVAILAKAACKVRSPARQD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PET54_SACBA
Sequence: MKGSSKAIKRVLEHLQSTGRVLGTVESKVPAGISEEAALSGGHQQLQIKKPLILQFRSYNPYLVKEDIVSILPENQYKKRGQFTNGLDFQLIKVRDPKYFQFKDQYYLLFNDHNSLVEYADLTRLSRINKVRVRMTPLMQPLPNLMTKFQRYSQNLHNAFQSSEKYFEGLTEKIDAKNMIDVTQLWRVLDSVREMESKSVLVWNFPTELQSSNILNYFWFYNIRSSFKMYWDDEMKRNLRFISFENSNDAYRFKRNYHGLLAKELLNPPRKEKDTLETNSVIDDSKLLIEHLNE
What is the function of this protein?
Activator of specific mitochondrial mRNAs.  PET54 is involved in the excision of intron aI5-beta from pre-mRNA for cytochrome c oxidase I (COX1) and plays a role in promoting the translation of COX3 (By similarity).
What are the official names of this protein?
Protein PET54, Petite colonies protein 54.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: SYGB_SHEB2
Sequence: MNFENLLIELGTEELPPKSLRKLAESFLANFTEELSKADLAFSSAVWYAAPRRLAINVTELALAQADKVVEKRGPAVSSAFDAEGKPTKAAEGWARGNGITVEQAERLVTDKGEWLVHNAKVEGVETKSLIAAMAQRALDKLPIPKPMRWGNNKTQFIRPVHTATMLLGSELIEGELLGIKSARTVRGHRFMGLKQFELAHADHYLADLKEKGKVIADYESRKALIKADAEKAAAKIGGTADIEDSLLEEVASLVEWPVVLTASFEEKFLAVPSEALVYTMKGDQKYFPVFDDAGKLLPNFIFVTNIESKDPAQIISGNEKVVRPRLADAEFFFNTDKKHTLESRLPSLETVLFQQQLGTLKDKVNRISALAAFIAEQTGANAVDAARAGLLSKTDLMTNMVMEFTDTQGTMGMHYARLDGETEAVAVAMEEQYKPKFSGDTVPSAGVSCAVALADKLDTLVGIFGIGQAPKGAADPFALRRAAIGVLRIIVENKLPLDLVDLIAKAQALHGTNLSNANASDEVLEFLMARFRAWYQDKGIGVDVILAVLARRPTRPADFDSRINAVSHFRSLEASSALAAANKRVSNILAKVEGALPTTINASLLTEAAEQALAAKLNELQPLLAPLFANADYQQALTLLAGLRESVDQFFEDVMVMADDEALKNNRLALLNNLREQFLHVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_GEOKA
Sequence: MAKALPIMFQGTHSDAGKSVIATAFCRMFAQDGWKTAPFKSQNMSLNSYVTPDGNEIGRAQGIQAEAAGVAARAEMNPILIKPSREHESQIVVLGKPYGNMQAFAYRNEFFHQGLAVIRQSLETLMNEYDRIVIEGAGSPAEVNLNDRELVNMRIARLANAPVVLIGDIERGGVFASLVGTLSLLEPEDRKRVIGVIINKFRGDVALLKPGLDWFEQHTGVPVLGVVPYLPDLAIDAEDSLSLERFASSVGGEEAIDVAVIRCPKIANFTDIDPLLAEPDCRVRLVTHGDELGAPDVIVLPGSKNTIEDLIYMKKRGLASRIVSLVNEGKARVVGLCGGYQMLGAVIRDPYGVETPLPEVKGLGLLPIETTLERTKITIRTEGMLTWAGERFSVQGYEIHMGRSAPLPGYAPLIEADGRHEGAKHSDERVLGTYMHDLFHNDAFRTAFFNNIRRQKGIAPSGVRLFRSLKEKAFDRLAAHVRQHVAVERIEQMMRQFGCRDHS
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: TRM11_HUMAN
Sequence: MALSCTLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETYGKSPFWILSIPSEDIARNLMKRTVCAKSIFELWGHGQSPEELYSSLKNYPVEKMVPFLHSDSTYKIKIHTFNKTLTQEEKIKRIDALEFLPFEGKVNLKKPQHVFSVLEDYGLDPNCIPENPHNIYFGRWIADGQRELIESYSVKKRHFIGNTSMDAGLSFIMANHGKVKENDIVFDPFVGTGGLLIACAHFGAYVYGTDIDYNTVHGLGKATRKNQKWRGPDENIRANLRQYGLEKYYLDVLVSDASKPSWRKGTYFDAIITDPPYGIRESTRRTGSQKEIPKGIEKWEKCPESHVPVSLSYHLSDMFLDLLNFAAETLVLGGRLVYWLPVYTPEYTEEMVPWHPCLELVSNCEQKLSSHTSRRLITMEKVKKFENRDQYSHLLSDHFLPYQGHNSFREKYFSGVTKRIAKEEKSTQE
What is the function of this protein?
Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
What are the official names of this protein?
tRNA (guanine(10)-N2)-methyltransferase homolog, tRNA guanosine-2'-O-methyltransferase TRM11 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.
Protein: HTPG_CLOBM
Sequence: METKQFKAESKRLLDLMINSIYTHKEIFLRELISNSSDAMDKIYYKTLTEDSLKFERDDYYIKVVFDKENRVLKIADTGIGMTKEELENNLGVIAKSGSLQFKKENEVKEGYDIIGQFGVGFYSAFLVSDDVTVISKAFGSNEAYKWNSKGAEGYTIEPCEKEAYGTEIILKIKDNTEEENYDEFLDEYTLKSIIKKYSDFIRYPIKMDLTKTKPKEDNKEEFEEYKEEETINSMVPIWRKNKNELKAEDYENFYAEKHYGFDKPIKYIHTSVDGVVSYNAILFIPETTPYDFYTKEYEKGLELYSSGVLIMNKCGDLLPDYFGFVKGIVDSEDLSLNISREILQHDRQLKLIAKNIKTKIKNELESLLKKERDKYEKFYESFGRQLKYGVYSDFGSNKDILQDLLMFYSSKEKKMVTLAEYVSRMPEDQKYIYYAVGESNERIEKLPQIEGVLDKGYEVLYFTDDIDEFAIKMLMNYKEKEFKSVSSGDLGIEGEEKENTSSSDDKENKELFESMKDILSGKVKDVRASKRLKNHPVCLANEGELSIEMEKVLNAMPNNQNIKADKVLEININHDVFKPLKEAYEGDKEKLKLYTDLLYNQALLIEGLTINDPVEFTNNICKIMK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXS_BACCQ
Sequence: MTNVTGTERVKRGMAEMQKGGVIMDVINAEQAKIAEEAGAVAVMALERVPADIRAAGGVSRMADPTIVEEVMGAVSIPVMAKCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKRDYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVEAVRHMRQVNAEIRQVASLREDELMTYAKNTGAPYEVLREIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSENPAKFARAIVEATTHYEDYELIASLSKGLGNAMKGIEISTLLPEQRMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: IF2_SHISS
Sequence: MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEAHRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YE067_YEAST
Sequence: MTQPLICAYRMCFVIDKYHSIFMCANYLNVYLERSTMVFSFLTVMPGDFIKCLFLRFFVKFKLRFPNGLLNIFQKMLFNMLVQVTHELLRMRICSITNFFRVLVRLV
What are the official names of this protein?
Putative uncharacterized membrane protein YER067C-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PANB_MYCLE
Sequence: MSEQNVNVYGADPSTSSIQSIQRTKIRTKHLQKMKAEGHKWAMLTAYDYSTARVFDEAGIPVLLVGDSAANVVYGYDTTVPVSADELLPLVRGVVRGAGHALVVADLPFGSYEPGPTAALAVATRFMKEGGAHAVKLEGGQRVAEQIACLTAAGIPVMAHIGFTPQSVNSLGGFRVQGRGGDAEQTVADAVAVAEAGAFSVVMEMVPTELATQITGKLTIPTIGIGAGLNCDAQVLVWQDMAGLSSGKVARFVKQYADIAGELRRAAMQYAEEVASAVFPAEEHCF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR2_CHITE
Sequence: MTGKKLLLIGSGGREHALAWKLQQSKNVTEIFAFPGSIGISQLEKVQLVNNNEMNLKDFKGIASWCKINHIDLVIVGPEDPLAEGIADQLKAANIHCFGPSKAGARIESDKSWSKDFMIRHHIPTAQYGSFIDALKAKDFIRNTPNALVVKASGLAAGKGVIVAENIEEACAAVDEILGDHKFGTAGDVVVVEEKLSGQEVSVLGFVDSNSVRILPPAQDHKRLKDNDEGLNTGGMGAYCPCPLISQQELDIVKSQVLQRAVDGLRKENILYNGILYAGIMLTHDGPKTLEFNCRFGDPETQIILPLLDEDLYDLMMASCTNHLCNVPELKFKSNINAVGVVMASKGYPETSTKGCVISGIESVETMDNHIVFHSGTSKNNKDEWITNGGRVLINIALADNLKKAADLATKACDVVKFDGSQYRRDIGKKAFQIHSLTYKESGVNIEAGNSLVGRIKSLSYGTHRSGVVGQIGSFGGLMRLNDIKYINSNGEESNYKDIVLVQGTDGVGTKLKIAESMNVWDTIGIDLVAMCVNDVLCNGAEPIGFLDYIACGHLEVPTVATIVKGIADGCRKANCALIGGETAEMPSMYGKGKYDLAGYCVGITEYDEILPKINDVHVGDVVIGLPSSGIHSNGFSLVNKIFQQTGFKLTDIAEFSDSHKSYGMEFLTPTRLYVSETLPFLRNGYVKALAHITGGGLLENIPRILPNHLSVQIDALTWKLPKVFSWLAAHGNVNANEMLRTFNCGIGMIIIMPRNDIEWETIPEARMIGSITQRDHNGPQVIVKNFKEVLHKEVTHWKKGDAETTSISYKDSGVDITAGNELVDNIKPHAKSTNRKGVIGGLGSFGGLFRINECGTKFEDPMLVLATDGVGTKLKIAQQLGKHDTVGIDLVAMCNNDILCNGAEPLTFLDYFACGKLDVNVATNVVSGIAEGCRQSDSTLLGGETAEMPGMYNPNVYDLAGFSLGVAEHEDILPKKNCLEVGDIIIGFPSNGVHSNGFSLIHKLFELTGYKWTDIAPFSAYGKTFGEEFLEPTKVYVKEISPALKTGYVKALAHITGGGLWDNIPRVLPYNLTAELDAKKINISPVFAWLSLNGNIDKLELLKTFNCGIGMIMIASKEHELEILKSLYGSRASVIGKIIPTKPHGHQVIVRHFATCFERVERLLSIPKKRVGVLISGSGSNLQALIDATKSTNMGMCSEIVFVLSNKAGIFGLERAAKANIPSTVISNKDYATREAFDVALHNELIKHNVEIICLAGFMRILTPCFVNKWKGKLLNIHPSLLPKYKGITAQKDALESGDNESGCTVHFVDENVDTGAIIVQEIVPIFENDTVESLTERIHVAEHIAFPKALRLVASGYVRLNDKCETEWA
What is the function of this protein?
Trifunctional enzyme that catalyzes three distinct reactions as part of the 'de novo' inosine monophosphate biosynthetic pathway.
What are the official names of this protein?
Trifunctional purine biosynthetic protein adenosine-3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GART family.
Protein: RSMG_RICFE
Sequence: MMEVPREIIEKLEIFQKLVKKWNKSINLVSDNTIHNFWQRHILDSLQLMQYIDNKEIHLVDIGSGAGFPGIVLSIAGVAKVSLIEADLRKCIFLEKASKISNNNIQIINQRIEKVEIDCSILTCRAFSKLNTIFNCIKNISVQEKFLLLKGKNYLTEIVEAKEMWLFDYLIHQSITCEEGKILEVSNLTKII
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGRF1_MOUSE
Sequence: MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFSTRAFKKQMRQVKNPFGLEITNSSAASLATGMALRTDCLEDSRLTCYWGCSVQKLYEALQKHAYCFRISTPQALEEALYSDYLHREQYFIKKHSKEEIYCQLPSDTEIEDFGPVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLPCRILYQYLILAQGQFYDLKQLFMSANNSPPPSNDESPEDRSVEQSLLEKVGLAGNDGDPVEESSRDCVVCQNGGVNWVLLPCRHACLCDSCVRYFKQCPMCRQFVQESFALCGQKEPDKDLLETS
What is the function of this protein?
Able to inhibit growth in several cell lines.
What are the official names of this protein?
Cell growth regulator with RING finger domain protein 1, Cell growth regulatory gene 19 protein.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum.
Protein: PSBD_NYMAL
Sequence: MTIALGRFTKEENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYN_PSEA6
Sequence: MAQAPVADIFAGKYSVGQQVTVKGWVRTRRDSKAGLSFVALHDGSCFDPIQVIALNTLNNYADIQRLTTSCSIIATGVLKESQGQGQSLEIEADEIEIVGWVENPDTYPMAPKRHSLEYLREHAHLRPRTNVIGAVTRVRNCLSQAIHRFFHENGYCWVSTPILTASDTEGAGEMFRVSTLDMMNVPTTEQGQVDFSQDFFGKETFLTVSGQLNGETYATAMSKIYTFGPTFRAENSNTSRHLAEFWMIEPEVAFADLSDIAQLSEDLLKYVFKAVLAERADDMAFFAQRINKDAITRLEKVIEQDFVRMDYTDAIEILQNCGKKFEFPVSWGVDLSSEHERYLAEEHVGAPIIMQNYPKDIKAFYMRINDDNKTVAAMDVLAPGIGEIIGGSQREERLDVFDRRLAEMGLDQEDYSWYRDLRRYGTVPHSGFGLGFERLVAYVTGMQNVRDVIAFPRTPGNANY
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMOC2_MOUSE
Sequence: MLPPQLCWLPLLAALLPPVPAQKFSALTFLRVDQDKDRDCSLDCPSSPQKPLCASDGRTFLSRCEFQRAKCKDPQLEIAHRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRCPGSINEKVPQREGAGKADDAAAPALETQPQGDEEDIASRYPTLWTEQVKSRQNKTNKNSASSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKNRPLQGCPGAKKHEFLTSVLDALSTDMVHAVSDPSSSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDMNNDKSITVQELMGCLGVTREEGKANTRKRHTPRGNAESSSSNRQPRKQG
What is the function of this protein?
Can stimulate endothelial cell proliferation, migration, as well as angiogenesis (By similarity).  Promotes matrix assembly and cell adhesiveness.
What are the official names of this protein?
SPARC-related modular calcium-binding protein 2, Secreted modular calcium-binding protein 2, SMOC-2.
Protein: TENS3_MOUSE
Sequence: MEDSHELDLTYVTERIIAVSFPASCSEESYLHSLQEVTRMLKCKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNNDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKISALMEPSQKRYVQFLSGLLSGAMKMNTSPLFLHFVIMHGVPSFDTGGACRPFLKLYQAMQPVYTSGIYNVGSENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGSEHLYSDQGVTVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDTGIPSSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERLTPGARRGLSPQEKAELDQLLSGFGLEDSASSHKDMTDMRSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSTHLGPFTCLKSSQNSLLSDGFGNGVAEDHNGVLSPDLGLGVDTLYDRERMCGGREQKPLQPLLRKPSAPTPVQAYGQSNYSTQTWVRQQQMVAAHQYSFASDGEARLGSRSTVDNTGLAQPPPHIPVTPNRGASSRVAVQRGISNGPNPPDTQQLCPGKALQPRFQDDRVTNGVHQEPNTGSSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHLNALGISAVCPDGVGSGLRCSGRLDSVDGPGRSPGRQGDDPIGGRLRKLSIGQYDNDAASQVTFSKCGWGKAGVDPAPSLGSFSSPEDIKETVITAYPSDLNMIDGRIPNSKESSMCLTPSFPVSPETPYVKTSPRYPPFSPPEPQLSSPASLHKGREPRGCPEIISHTVGMSESPVGPKPTMLRADMPATPNFQQVFASSCTVSSNGPGQRRESPPSAERQWVESSPKSTLTLLGNSHPSESPLGTHEFCSSGKDSPGLPCFQSSELQASFHSHELSMSEPQGALPPAGSQTFLGFNTVTTATSVLPPGEDAGTLLVNSHGTSPAPGTPLLTTGAADNGFLPHNFLTVSPGASSHHSPGLQNQNVSLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVASPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALSMTLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI
What is the function of this protein?
May act as a protein phosphatase and/or a lipid phosphatase (Probable).  Involved in the dissociation of the integrin-tensin-actin complex (By similarity).  EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1 (By similarity).  Increases DOCK5 guanine nucleotide exchange activity towards Rac and plays a role in osteoclast podosome organization (PubMed:27505886).  Enhances RHOA activation in the presence of DLC1 (By similarity).  Required for growth factor-induced epithelial cell migration; growth factor stimulation induces TNS3 phosphorylation which changes its binding preference from DLC1 to the p85 regulatory subunit of the PI3K kinase complex, displacing PI3K inhibitor PTEN and resulting in translocation of the TNS3-p85 complex to the leading edge of migrating cells to promote RAC1 activation (By similarity).  Meanwhile, PTEN switches binding preference from p85 to DLC1 and the PTEN-DLC1 complex translocates to the posterior of migrating cells to activate RHOA (By similarity).  Acts as an adapter protein by bridging the association of scaffolding protein PEAK1 with integrins ITGB1, ITGB3 and ITGB5 which contributes to the promotion of cell migration (PubMed:35687021).  Controls tonsil-derived mesenchymal stem cell proliferation and differentiation by regulating the activity of integrin ITGB1 (By similarity).
What are the official names of this protein?
Tensin-3, Tensin-like SH2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PTEN phosphatase protein family.
What are the subcellular locations of this protein?
Cell junction, focal adhesion.
Protein: TAL_XANOP
Sequence: MTASPSKLAQLRELSVVVADTGDYDAIKRLQPVDCTTNPTLVKKALDLPVYADLLERELAWGRAHGGDDRTTTVDEVADRLTIGVGVKLSALVPGRVSTEVDADLAHDTQATIAKARKFVAMYAERGVPKDKILIKIAATWEGIEAARQLQLEGIDCNLTLIFNRAQALACAEANVFLISPFVGRILDYYVAQGQTPASIDEDPGVVFVRTVYNAFKQRGSSTVVMGASFRSTAQIEALAGCDRLTISPDLLEKLDAEHGELPRKLSPGNANNAQITPIDSDSFASGLAADPMATEKLASGIDTFAKDLHALRKTIADKLAG
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_MYCUA
Sequence: MTERAGLRLHDTAAGAVRDFVPLREGHVSIYLCGATVQGLPHIGHVRSGVAFDILRRWLMARGFDVAFIRNVTDIDDKILNKAAAAERPWWEWAATYERAFTAAYDALDVLPPSAEPRATGHVTQMVELIERLIERGHAYAGGGDVYFDVLSYPDYGQLSGHKVDDVHQGEGVATGKRDQRDFTLWKGAKPGEPSWPTPWGRGRPGWHLECSAMARTYLGAQFDIHCGGMDLIFPHHENEIAQSRAAGDGFARYWLHNGWVTMGGEKMSKSLGNVLAIPTMLQRVRPAELRYYLGSAHYRSILEFSDIALQDAVNAYVGVEEFLHRVRSRVGAVVVGDWTPRFAAALDDDLSVPIALAEIHHIRAEGNRALDAGDHDAALQSASSIRALMGILGCDPLDERWESRDETSAALAAVDVLVQAELENRQKAREERNWALADEIRNRLKNAGIEVTDTADGPQWLLGGDGK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRPRB_DICDI
Sequence: MKDSAILNQLKVVLPPHIMEIIYFRYNQIDTYLKPYNLPIKTDVLLLALFTLIFIIIISKLFGSSGNKTRSVGGRTSNDKKVKRGVNIAILGLSNAGKTALLLNLTNVDKKISTHTSITTNNGVYITENKKKLPIIDVPGNGKAKASLPKILSNSACIIYVIDGTTFIDNSTQEAQYLYDILTNESVYQKKIPVLVFNNKMDLDSTIDTEQVKNILERELDDLRRTRGATPIVLGQEEDKKDIYLGIEGTPFQFDHLPNDVQFSNGSASPSNGELKEIDDIKNFIQTTTL
What is the function of this protein?
Component of the signal recognition particle (SRP) complex receptor (SR) (By similarity).  Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity).  May mediate the membrane association of SR (By similarity).
What are the official names of this protein?
Signal recognition particle receptor subunit beta, SR-beta.
What is the protein family that this protein belongs to?
Belongs to the SRP receptor beta subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: CF251_PONAB
Sequence: MSDAEEAPREATRENGETEMKEEEEPNPNYKEVEDPQQESKDDTLAWRESQEEERKTGEEEGEEEEEKEEEGKKDKKIVMEETEEKAGESQEKEASGIQEETTVEPQEVTESMIRLETQITDSQSVTSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQLEFLDLDQISPEEQQISSPERQPSGELEEKTDQMPQDELGQERRDLEPENREEGQERTVSDIQSKAGISRESLVSSTTEDILFQKDKSAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNVFRNNQYHLQGHANIISCLCVSEDRRWIATADKGPDCLVIIWDSFTGIPVHTIFDSCPEGSGIRAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPTNNKELVSNSKTWAIYYAWYEERDTLAHSAPLLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKEGITVLTTTDSYIVTGDIKGNIKFYDHTLSIVNWYSHLKLGAIRTLSFSKTPATPPTEKSNYPPDCTLKGDLFVLRNFIIGTSDAAVYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADRSFTVAVYMLVVRNGQRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIGYDLLRSYKDCLEVLDIHHTDQGCYPTCMVWYPPLTRELFLLICNSGYKVKLFNATTKMCRKTLLGPAYGSPIEQTQVLPVRSMAELQKRYLVFINRDKVGLQILPVDGNPHKTSAIVCHPNGVAGMAVSYDGHYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGLLSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKIDDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGKKAIRREDFLRLLVTKGEHMTEEEMLDCFASLFGLNPEGWKSEPATSSVKGSEICLEEELPDEITAEIFATEILGLTISEYSSQDGQ
What is the function of this protein?
Involved in spermatozoa motility (By similarity).  May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 251, WD repeat-containing protein 66.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.
Protein: RL30_BACAC
Sequence: MAKKLEITLTRSVIGRPQDQRATVEALGLKKLNSTVVKEETPAILGMINKVSHLVTVKEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TRMA_HAEIN
Sequence: MQLPISQYNELLQKKLEKLTALLHPFNAPDIQVFDSPTSHYRMRAEFRIWHEQDDFYHIMFDQATLQRYRVDEFPIASMLINRMMQTLLPLLKQQEVLHKKLFQIDYLSTLSNKIIVSLLYHKTLTEEWESAAKNLKDLLEKQDFDVQIIGRASKQKICFEQDYVDEVLPVNGRNYVYRQVENSFTQPNATVNCKMLEWAIDCTQNSEGDLLELYCGNGNFSIALAQNFRKVLATEIAKPSVAAAQFNIAENKVDNLQIIRMSAEEFTQAMNGVRAFNRLKGIDLKSYECNTIFVDPPRAGLDPDTVKLVQNYDRILYISCNPHTLCDNLVELSKTHRIEKAALFDQFPYTDHMESGLWLIRK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.