PharMolix/UniProtQA huggingface dataset:
Protein: GLYA_PELTS
Sequence: MSLKRPLSEVDPEIFRAIELETQRQRNTLELIASENVASRAVMEAQGSVLTNKYAEGYPGRRYYGGCEFVDIAEDLAISRAKELFGAGFANVQPHSGAQANTAVYFALLNPGDTIMGMDLAHGGHLTHGSPVNISGRYFKFTFYGVEKETGRINYEKMFSIAFEHKPRMIVAGASAYPRAIDFYKIKEIAAEVGAYLMVDMAHIAGLVAAGLHMSPVPYADVVTTTTHKTLRGPRGGLILCKDAERYGTKINRAVFPGVQGGPLMHVIAAKAVAFKEAMEPGFKEYQRKIVSNARALADALLERGFELVSGGTDNHLILVDLRSKKITGREAQELFDAVGVTVNKNAVPFDPQPPNIASGIRIGTPAVTSRGLNEDDMVQIAEIMDYAIEHRDDRGKLEKARAKVDEICARYPLY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTPE_MYCBO
Sequence: MTRSASATAGLTDAEVAQRVAEGKSNDIPERVTRTVGQIVRANVFTRINAILGVLLLIVLATGSLINGMFGLLIIANSVIGMVQEIRAKQTLDKLAIIGQAKPLVRRQSGTRTRSTNEVVLDDIIELGPGDQVVVDGEVVEEENLEIDESLLTGEADPIAKDAGDTVMSGSFVVSGAGAYRATKVGSEAYAAKLAAEASKFTLVKSELRNGINRILQFITYLLVPAGLLTIYTQLFTTHVGWRESVLRMVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVVCADKTGTLTESGMRVCEVEELDGAGRQESVADVLAALAAADARPNASMQAIAEAFHSPPGWVVAANAPFKSATKWSGVSFRDHGNWVIGAPDVLLDPASVAARQAERIGAQGLRVLLLAAGSVAVDHAQAPGQVTPVALVVLEQKVRPDARETLDYFAVQNVSVKVISGDNAVSVGAVADRLGLHGEAMDARALPTGREELADTLDSYTSFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIGVAMGSGSPASRAVAQIVLLNNRFATLPHVVGEGRRVIGNIERVANLFLTKTVYSVLLALLVGIECLIAIPLRRDPLLFPFQPIHVTIAAWFTIGIPAFILSLAPNNERAYPGFVRRVMTSAVPFGLVIGVATFVTYLAAYQGRYASWQEQEQASTAALITLLMTALWVLAVIARPYQWWRLALVLASGLAYVVIFSLPLAREKFLLDASNLATTSIALAVGVVGAATIEAMWWIRSRMLGVKPRVWR
What is the function of this protein?
P-type ATPase involved in specific uptake of calcium.
What are the official names of this protein?
Calcium-transporting ATPase CtpE.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARLY_THET2
Sequence: MAHRTWGGRFGEGPDALAARFNASLAFDRALWREDLWQNRVHARMLHAVGLLSAEELEAILKGLDRIEEEIEAGTFPWREELEDVHMNLEARLTELVGPPGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEKHLDPLYVLPGYTHLQRAQPVLLAHWFLAYYEMLKRDAGRLEDAKERLNESPLGAAALAGTGFPIDRHFTARELGFKAPMRNSLDAVASRDFALEVLSALNIGMLHLSRMAEELILYSTEEFGFVEVPDAFATGSSIMPQKKNPDILELIRAKAGRVLGALVGLSAVVKGLPLAYNKDLQEDKEPLLDALATYRDSLRLLAALLPGLKWRRERMWRAAEGGYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEEGRALKDLTLEELQAHHPLFAEDALPLLRLETAIHRRRSYGGTAPEAVRERLEEAKKEVGLD
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_LACLS
Sequence: MENFYKVGTIVNTQGLQGEVRVLPSTDFANERFSKGAVLALFDDKDNYIQDLKVKSGRLQKNFYVVKFEGFYHINDVEKYKGYVVKIAQENQEELNDGEFYYHEIIGSDVYENDILIGQISEILQPGANDVWVVKRKGKRDLLLPYIPPVVLKVDVAQHRVDVDIMEGLDD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_CORMA
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKMK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GTSF1_MOUSE
Sequence: MEDTYIDSLDPEKLLQCPYDKNHQIRACRFPYHLIKCRKNHPDVANKLATCPFNARHQVPRAEISHHISSCDDKSCIEQDVVNQTRNLGQETLAESTWQCPPCDEDWDKDLWEQTSTPFVWGTASFCGNNSPANNIVMEHKSNLASGMRVPKSLPYVLPWKNNGNAQ
What is the function of this protein?
Required for spermatogenesis and is involved in the suppression of retrotransposon transcription in male germ cells.
What are the official names of this protein?
Gametocyte-specific factor 1, Protein FAM112B.
What is the protein family that this protein belongs to?
Belongs to the UPF0224 (FAM112) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPM1D_HUMAN
Sequence: MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDNQGNFTNEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVKSLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAEIARENVQGVVIPSKDPEPLEENCAKALTLRIHDSLNNSLPIGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEESNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLLHQHRKTVCVC
What is the function of this protein?
Involved in the negative regulation of p53 expression (PubMed:23242139).  Required for the relief of p53-dependent checkpoint mediated cell cycle arrest.  Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins (PubMed:15870257, PubMed:16311512).  Mediates MAPK14 dephosphorylation and inactivation (PubMed:21283629).  Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity (By similarity).
What are the official names of this protein?
Protein phosphatase 1D, Protein phosphatase 2C isoform delta, PP2C-delta, Protein phosphatase magnesium-dependent 1 delta, p53-induced protein phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: LAC1_NEUCR
Sequence: MKFLGIAALVAGLLAPSLVLGAPAPGTEGVNLLTPVDKRQDSQAERYGGGGGGGCNSPTNRQCWSPGFNINTDYELGTPNTGKTRRYKLTLTETDNWIGPDGVIKDKVMMVNDKIIGPTIQADWGDYIEITVINKLKSNGTSIHWHGMHQRNSNIQDGVNGVTECPIPPRGGSKVYRWRATQYGTSWYHSHFSAQYGNGIVGPIVINGPASANYDVDLGPFPLTDYYYDTADRLVLLTQHAGPPPSNNVLFNGFAKHPTTGAGQYATVSLTKGKKHRLRLINTSVENHFQLSLVNHSMTIISADLVPVQPYKVDSLFLGVGQRYDVIIDANQAVGNYWFNVTFGGSKLCGDSDNHYPAAIFRYQGAPKALPTNQGVAPVDHQCLDLNDLKPVLQRSLNTNSIALNTGNTIPITLDGFVWRVNGTAININWNKPVLEYVLTGNTNYSQSDNIVQVEGVNQWKYWLIENDPDGAFSLPHPIHLHGHDFLILGRSPDVTAISQTRYVFDPAVDMARLNGNNPTRRDTAMLPAKGWLLIAFRTDNPGSWLMHCHIAWHVSGGLSNQFLERAQDLRNSISPADKKAFNDNCDAWRAYFPDNAPFPKDDSGLRSGVKAREVKMKW
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase, Benzenediol:oxygen oxidoreductase, Diphenol oxidase, Urishiol oxidase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: DDAC_ENTAG
Sequence: MSHSYNVRPLVSGAPHVSLVTASTSDASIDEFFSHHPIDEILSEKGALLFRGFSINEDQQFSQLVSILAKEELTYQERSTQRKKTAQGVYTSTEYPAAKTIANHSENAFQQVVPGKILFYAHQAALKGGETPIADNSRVLSLIDEEIVAEFRQKGIRYLRNFDGGFDLSWQEAFQTEKKREVETYCVKNAIDCEWLSDSHLRTSQLRSATRRHPLNRKEMWFNQLHLFHITNLELPVRQALLASLGHDLLPRHAVYGTGEEIPDEVVDHIRAALVKAELVFPWQTGDVLIADNILVSHGRKPFEGERAVRVALIDPVYPSAEENPHAQR
What is the function of this protein?
Involved in dapdiamide antibiotics biosynthesis.  Catalyzes the alpha-ketoglutarate-dependent epoxidation of the covalently bound N-beta-fumaramoyl-DAP-S-DdaD to generate N-beta-epoxysuccinamoyl-DAP in thioester linkage to DdaD.
What are the official names of this protein?
Dapdiamide synthesis protein DdaC.
Protein: TRPD_GEOKA
Sequence: MLKQLLSKCAEGKALTEDEAYAAMNIIMSGEATDSQIASLLSMLRLRGETVDELVGFVRAMRDRMTAIEASDDVIDTCGTGGDGAATFNVSTAAAIVISSLGVKVAKHGNRAVSSKSGSADVLERLGIDIQTSPSAAKQALETKGLAFLFAPLYHAAMKHAAGPRKEIGFRTVFNLIGPLANPARCKRQVVGVYSTCYAEKLAEAMRRLGSEHVLFVTGRDGLDECSIAAETDVVELKDGAIRRFVIAPEDAGLPRGELADVQVRDPEESAALLEAVMAGTAPESAINIVALNAGAALYAAGKAETIAEGVAMAKEAILSKTAYEQLQRLRAKEVIHDA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: YLJ2_CAEEL
Sequence: MKAIIHDDTVVREIEGQRVQVLQKFADFELKAINKRSSIIQSRQLQVYLRSAAEFKQVIESLIESSEAVVTSQCSESSIRGQKVIGRLQQEADGKHNNLPMLENEAARLLKEGHYASDEIQKTFNNVLSRWEYLLKLLALKWRQLEKEIESIEFKNKCDSIVDWILKIKESDESGKEIFDEIRKCSMVWNEISATFQQMLDPTATDTSNYEKVHETWSNFQEYIDSLHKKLSENERFQKFVDNAEDLIKWMDDKEKEICEKYSKMDFEVMMKYRKTVEIEMKSVEQRIKDLKEQFVGMENDNLRNIPDPKNHVIDVEQRFESFQAFVQKWKTDIENSADADKLMKEAENICCWSSEKIEDLKIMATSDTPDCDEIIMWIETNNFDFNSWDNVVVQFLASSQELLNKQNNGNVKQEVERTTELYELAKRTMKTCNEFLEDRIQTINMEKLIFQTHQKAVILASFLQNHEESPEDMNAEDIEKEIRVIDGITVRCTSVVEQIENIEDELRQKPEQLNQLSVYASKQVNDLNEMKEVLKTTVNSRKAILQRLLDVTYFLDNCCETRKHTDTMLSNVKSSRVKLEIVQPIKDQLDSLKVEMVDMMLDDQQKNMANEELRKTYENLKKIEMEVGRQASQKEARKAADRTEAFVGRVQNWIDNNQIQDDTDIVSETVNLRRTTTHYQHLLSICASYKKSIDSKLEELANVYTDNDPRCLLEGIQNSVENFEVKIHQKVDDTKKLLHITENMNELNSQNEWIRAKIKSLSAEPLWDSLLIAQKMRRRHDNDFEEIANRRKQITEVIQKSATTKDQPILLEIEQNWDRMKDLFDERGGVLERIIKLYEYDEESSTTSEWLREKMICADTIEPKEDESFNEVMVKKLEALTEEVENYKPRIVETHALLEDALVTPNTKDSTSQQTMKLKAVLARKQGEIESDYKALKKLVERKLKTLKAILQDADISHQIADIEQWIEVEQNQLNRYLASDSDELPTKLDDVMTNIQRRRSNLTDIKCNVVGQVQMQKIDDAFGMLDVFSFEVHRIRQKACRLEIFKKLESQTEDVIDAIQMKLEEINVSQSTSRKRQVAGDDLSNLAGDLETLRRRVVEALDRSKEVRAANADLAPQVYDTEERLEKQWTDVSKAYENHKKRMERCKILSELDNEMINMEQWIDTFNEEVTVVIGSIHDGLGVQVGLESIDTWREELSHRVDQLGGVKNSLSSVGNAITEQDKMDPWLERVSNIENNLVKARETIDTKQDDLCRFADILGAERDCERLYSWASGKRHQLETEATMCDAKTLVRRMNEVEKMMMSRIGEVDQLRDFLDNLKASKTSDTFQTTELENKFELLDVEWNHLEEELRRREVDLNDSMSQILIDEQFDTIRQWIKERTEALEADVEVSNKTKPDDIERMQKRHDELASDINDYHTIYEDFLNNGQVEEEKVQVIRHLWSSLIESSTTRQKSLAQECQKSRLFELLDGMSIWLIDAETDVHSTTNFIGLYNSVDAEKASRLLVSLGEQAGEKDDILIRIQCDESVDVIVEKLRNGISQLQMLIKANNEDLDVWKSMQKVVTAIDDEICWFKEINVIFSSTNVGNDVSSNDVLKRKHQRLQLETQRREQKVAKVVYLTTELVSSHRRPSLEYKFVEIDEKVAELTELLESNRQIAEIRTNRLEKWTEYFVTMNEIREKEQLLDQILDLKTGLPETVLADVERKLQVLETVGDHMDTLTIKAEQMSDDEVIRTKVAVTAIDQLRKKWLKMNEELKKMHQKIKESIEFTKFVSTCDTGIQCIREQEEKIGNLVRHQKPASNFENTAYHSTMTFVETYTKDTFEKLKVVCRKLQNSTDAEKKLSLVSERLNALKKQLDLLAEKIAVDDKFKLKVQNIQDEYSRTACELGNWLEQAEEDVSDVVWFQTKDSSEDCRETLLEILGTLRNEKSDLLGELELLEVELAELKEDVKTFTWHSFKTLATRMERLDQTISDRIRIADGEISRHSDNEKICEQAACTLKTYHNVIVDVKKELEILYSLKLEDQKKSLINLIDKVQKRGMIQDLEKWRSLMESRYIFNNKFSSATPHGVLVEMCQCLELMSSMLRSVEQSIADRNHNGVTEKQLHEFELAFDYFDRERNGWLDYKHFELCLKSQGYNFSAENTLKETMTLLDPSTTGHIQKHDYVRYMVKHETTNILDDHSAIEDALKNLDARKISDSMPRKEAEFFMSKIAKHAETSSDQVYLEYKDFVNSFY
What are the official names of this protein?
Uncharacterized protein C50C3.2.
What is the protein family that this protein belongs to?
Belongs to the spectrin family.
Protein: TRMD_ACIBT
Sequence: MFFAVITLFPEMFEAITAYGISGRAAKRDIVQVTCINPRDFAEGNYRRVDERPFGGGPGMVMMAEPLAKAINHAKQLASQAGCVHVPVVYMSPQGKTLNEQAVQQFVDYDGLIVLCGRYEGVDERLIQHYVDQEWSIGDYVLSGGELPAMVLLDSIIRRLPNVMSDEQSAIQDSFVDGLLDCPQYTKPDQFEGLDVPEILKSGHHANIEKWRFLQRYQRTLERRPELIEKVALTKQQKKWLSDEQG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDMA1_STEMA
Sequence: MSKADVVIVGAGHGGAQCAIALRQNGFEGTITVIGREPEYPYERPPLSKEYFAREKTFDRLYIRPPTFWAEKNIEFKLGTEVTKVDPKAHELTLSNGESYGYGKLVWATGGDPRRLSCQGADLTGIHAVRTREDCDTLMAEVDAGTKNIVVIGGGYIGLEAAAVLSKMGLKVTLLEALPRVLARVAGEDLSTFYQKEHVDHGVDLRTEVMVDSLVGENGKVTGVQLAGGEVIPAEGVIVGIGIVPAVGPLIAAGAAGANGVDVDEYCRTSLPDIYAIGDCAAFACDYAGGNVMRVESVQNANDMGTCVAKAICGDEKPYKAFPWFWSNQYDLKLQTAGINLGFDKTVIRGNPEERSFSVVYLKDGRVVALDCVNMVKDYVQGRKLVEAGATPDLEALADAGKPLKELL
What is the function of this protein?
Component of the dicamba O-demethylase multicomponent enzyme system involved in the degradation of the herbicide dicamba (PubMed:15855162, PubMed:15820213, PubMed:16535584).  In vitro, catalyzes the transfers of electrons from ferredoxin (DdmB) to NADH (PubMed:15855162, PubMed:15820213, PubMed:16535584).  Both NADH and NADPH support enzyme activity, with NADH being markedly more effective than NADPH (PubMed:15820213, PubMed:16535584).
What are the official names of this protein?
Dicamba O-demethylase 1, ferredoxin reductase component, Ferredoxin--NAD(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
Protein: PAN3_PHANO
Sequence: MATTFGSPSGDSRRGVASPRPKGREAKNTFCRNVTIYGHCRYENSKCRPPHLPDHVLNQNENAKKRFNVDSPSFTPLTTTPNGSVTASARNAAISPKAANAAVFTPKSQRSAVSTPNLHNKEPALDWHAPDFQEFVPETFGGPMVDSNASASYSGYDPYTSSANLASIAGQGHQSSAMNPYAQGHSGLEASYYQNPSAFQTSPAYHLYWPVGPQPTSLLGYQRTAHDFFIPDALREDLQKRAEVARQVMPNSTLPVIEQFHSLFCLDTTPQKNNAPFGYVSWIYKAISGKDGKTYALRRLENFRLTSEPAIRSAQAWKRIFNGSIVTIHEAFTTRAFGDSSLIIVTDYHPNSKSLADEHFKPMQRFNGRQATSSHVPEHVLWGYIVQIASALKAIHGSGLAARLISPSKTLLTAKNRIRLNACAIMDIVQFETARPVAEAQADDFVQLGRMILCIANNNTTAHLQMQKSMDHVTRNYTARLKECIQWLLNPQPPLGTPSSPTTPAPGSKDIDNFLGGISDQLASVFDSELHAQDTLTNTLGRELESSRIVRLLVKLNMVNERPELDASQQMSGGNTSNPSSVWAETGERYYLKLFRDYVFHQVDANGHPVTDLAHVLDCLNKLDAGTDEKIALISRDEQNVLIVSFREVKRGLEIAFQDLIRAGRGQGK
What is the function of this protein?
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.  PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex subunit PAN3, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. PAN3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_SHIFL
Sequence: MTLSPYLKEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLNGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGAT2_DANRE
Sequence: MKTILAAYSGVKKGSGSSILSALHDLPTVPWLTRSKMVKHLQVISVLQFIMTFLTMGIACSLLLMYMFCTDFWVISVLYVAWLIYDWNTPGQGGRRSTWVRDWTVWKYMRDYFPIRLIKTHNLLPSRNYIFGYHPHGILCFGAFCNFGTEATGFTKVFPGIKPSLATLAGNFRLPMFREYLMCGGICPVNRNSIDYLLSSNGTGNAVVIVIGGAAESLDCAPGRNSVMLKKRKGFVKLALKQGADLVPVYSFGENEVYKQLIFEEGSWWRTIQRKLQKFLGFAPCLFHGCGLFFPESWGLVPYCKPITTVVGEPITVPKIEEPTQDVIDMYHAMYIRSLKSLFDNYKTRFGLNESDTLIIH
What is the function of this protein?
Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.  Required for synthesis and storage of intracellular triglycerides.  Probably plays a central role in cytosolic lipid accumulation (By similarity).
What are the official names of this protein?
Diacylglycerol O-acyltransferase 2, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase, Diglyceride acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet. Cytoplasm, perinuclear region.
Protein: RS3A_PYRAR
Sequence: MAERQKAVAKQEKVTISKRDPWALKKWFAVHAPPYLGGVFLAEVPATEAEKLLMRTLEVSLYDITKDISHLPVKLKFQIHRVEGLRALTRFKGLELSRDYVKSLVRKGTSKVVAITEVKTKDGMDMRVSVMVITAHRLGTAQKSAVRKKITETLLKKASEMDTSQFLKEVLEGTLAADLFIAAKKIAPLRKVEFAKIKVLKYPPEEERVVVKEAVAEAAS
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: LPAR3_MOUSE
Sequence: MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDTSLTASLANLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVAVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCALQDSNTERRPSRNPSTIHSRSETGSQYLEDSISQGPVCNKNGS
What is the function of this protein?
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.  Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.
What are the official names of this protein?
Lysophosphatidic acid receptor 3, LPA receptor 3, LPA-3, Lysophosphatidic acid receptor Edg-7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ANM7_DANRE
Sequence: MKTFCGRANPTTGALDWVEESEEYDYHQEIARSCYADMLHDKDRNEKYYEGIRAAVRRVKARGERPVVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAQAASCIVERNGFSDKIKIINKHSTEVTVGPDGDMQERANILVTELFDTELIGEGALPSYEHAHMHLVQTGCEAVPHRATIYAQLVESDMLWKWAQMRPIDVDGHRLMPPGAVQECAGAPSVCDIQLSQVPTDAFTAISPVCTMFSVDFSKPVSSAAQSYTVRFKSQTGGRAQVVLSWWDIDMDPEGNIVCTMAPSWSYADPHAYPWRDHWMQSVYFLPAEENVSEGEELMLMVSHDDYSLWYSLTHSEQNDVRVAPFRPCCTCQAHLVWTRPRFGELNDEQRTESYVSALRSILKPDSVCLSVSDGSLLPVFAHLLGSKKVFSLESSGMAKQVIEQVLHTNSLKDGVQLLGIRAEQLSLADLDGNQISVLMGEPYFSTSLLPWHSLFFWYCRTAVAQLLQPDATILPRAATLYAVAVEFQDLWRIRFPCGTCEGFDVSPMDEMIQRSLDFRESWEAEPHPLWEYPCRALTKPCPVMTFDFTQCVPEQPISSDGAVPFTGRGRCHGVALWMEYQLTDDISVSMGLTKAVSQEGACEWNPHRKQGVFFFRSAKETSGDGREDLSYSLTFEPHSGDIKMDFSITES
What is the function of this protein?
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA.  Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles.  Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s.  Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites.  May also play a role in embryonic stem cell (ESC) pluripotency.  Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
What are the official names of this protein?
Protein arginine N-methyltransferase 7, Histone-arginine N-methyltransferase PRMT7, [Myelin basic protein]-arginine N-methyltransferase PRMT7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: RS18_MICLC
Sequence: MAKAELRKPKPKSNPLKAAKITEIDYKDVALLRKFISDRGKIRARRVTGVTVQEQRKIAQAVKNAREVALLPYAGAGRG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: LDH_GEODF
Sequence: MKIGIVGCGFVGATAAYAMVMRGVGRKLVMVDVNRARARAEAADISHAVPFAHALEVIAGEYEELEGASVVLVAAGVGQKPGETRLQLLERNAAIFKEVIPQVLRHAGDAVLLVASNPVDVLTHLAASIAGELGIPSSRVVGSGTTLDTARFRSLLSSSLGIDPRHVHAYVLGEHGDSEVLGWSTVTVGGMPLDAFAHRKGASFPPGLIASIDHQVRHAAYEIISGKQATYYGIGSALANIVEVMVYDRRSILTVCTPLPEVEGVENVTIALPHLVGGRGVLETFPPALDHMEREALRNSARIVRNAIESINV
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VA2_SOLIN
Sequence: MKSFVLATCLLGFAQIIYADNKELKIIRKDVAECLRTLPKCGNQPDDPLARVDVWHCAMAKRGVYDNPDPAVIKERSMKMCTKIITDPANVENCKKVASRCVDRETQGPKSNRQKAVNIIGCALRAGVAETTVLARKK
What are the official names of this protein?
Venom allergen 2, Allergen Sol i II, Venom allergen II.
What is the protein family that this protein belongs to?
Belongs to the ant venom allergen 2/4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL20_BART1
Sequence: MARVKRGVTAHAKHKKVLKQAEGFYGRRKNTIRAAKAAVDRSKQYAYRDRKNRKRTFRALWIQRINAAVRAEGLTYGRFIDGLSKAGIEVDRKVLSDIAIYEAEAFSALVASAKKALEYLKDTTPNAFEGAVK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RSMG_YERPN
Sequence: MLKKLDSLLTVAGITLPDQQKHQLIGYVELLDKWNKAYNLTSVRDPQQMLVRHILDSIVVNPHLQGSRFIDVGTGPGLPGIPLAIVRPDAHFTLLDSLGKRVRFLRQVQHELGLNNIEPVQSRVEAFTSEPPFDGVISRAFASLQDMLSWCHHLPAKPEGRFYALKGVRPDDELAVLPEDIVLESVIKLDVPELDGERHLIILKSN
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.