PharMolix/UniProtQA huggingface dataset:
Protein: RL14_CALS8
Sequence: MIQPQSRLKVADNTGAKEVMCIRVLGGSNRKFANIGDIIVCSVKDATPGGVVKKGDVVKAVIVRTRKGIRREDGTYIRFDDNAAVLIREDKTPRGTRIFGPVARELRDKDFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TPMT_PSEMY
Sequence: MHESFWQERWARDQIGFHLDQVNPYLLRHWPNLDVPAGARVLVPLCGKSLDLAWLAGQGHRVLGVELAEKAVQDFFAEQGLQPEIVQRGAFQVYRAGAVELWCGDFFALRPEDVADCLALYDRAALIALPPQMRERYAAHLTAILPGACRGLLITLDYLQSQMDGPPFAVSDGEVQAHFAAAWQLKTLQREDVLAGNWKFIRHELKALDEVVYRLNKRE
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BACC7
Sequence: MFVDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFVVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGRKSEDLIVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVIVHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTRQGVRDLLFEVANLIETTPEFPIHEVADESDTSVMYKFDTEGVKFEITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGMGIDEALRARGAKDGDIVKILEYEFEFID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_PORGI
Sequence: MKKFIQDFKAFALKGNVVDMAVGVIIGGAFGKIVTSLVNDIMMPPISLLTGGVNFTDLKLVLSKAVVEGGEVVKPEVSWNYGNFIQTTVDFLILAFVIFLMIKAIMAAKRKEEEAPAAPAPTPPEIELLTEIRDLLKKQ
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCED1_MAIZE
Sequence: MYYPQPTVSLAAAVALLRPSLRRHSQRASSLLRSSTPPPWVSARRRTAVSDDFFTVELDATGVEPEPDSIDDGLPSPWEGAVVYRRDAAVQHLEYASTLERLGLGDLSSPDSRARAADLGLAGGTLDSTGAQPRTPVLVSVDVTRRRGRLRLDGIVRTVITLGCFRCAEPAPQGIFANFSLLLTEDPVEEEPDLGTIFQEDDDKGGASLACAMDGDQDIDWDDRLHFPAADKEIDISKHIRDMIHLEITLDAVCNPNCKGLCLTCGANLNTTSSCTCKPRNVQGLSPLKGVFK
What is the function of this protein?
Plays a role in synthesis, processing and/or stability of 23S rRNA.  Required for embryogenesis.  May be involved in RPL23 transcript levels regulation in non-photosynthetic plastids.
What are the official names of this protein?
Large ribosomal RNA subunit accumulation protein YCED homolog 1, chloroplastic, 23S rRNA accumulation protein YCED, Large ribosomal RNA subunit accumulation protein YCED, Protein DUF177A.
What is the protein family that this protein belongs to?
Belongs to the DUF177 domain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CLPP2_CHLPN
Sequence: MTLVPYVVEDTGRGERAMDIYSRLLKDRIVMIGQEITEPLANTVIAQLLFLMSEDPKKDIQIFINSPGGYITAGLAIYDTIRFLGCDVNTYCIGQAASMGALLLSAGTKGKRHALPHSRMMIHQPSGGIIGTSADIQLQAAEILTLKKHLANILSECTGQPVEKIIEDSERDFFMGAEEAISYGLIDKVVTSAKETNKDTSST
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS2_ACIFR
Sequence: MSEVQDYKSRLSDPASAKFETLSYLPALTADEIRQQVAYIVSKGWNPAVEHTEPENAFGNYWYMWKLPMFGETDVDTILKEAERCHKRNPHNHVRIVGYDNFKQSQGTSLVVYRGKTV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit 2, RuBisCO small subunit 2.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
Protein: RS9_ECO81
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: LEUC_HALOH
Sequence: MGMTMIEKIIAAHTNRDKVKPGDIVNARIDFVLGNDVTTPVAVKEFNKIGIDEVFDQDRIAIVPDHFTPNKDIKSAEQCKFIREFARDKGIHNYFEIGEMGIEHCLLPEKGLALPGEIIIGADSHTCTYGALGAFATGVGSTDMAAAMATGYTWFKVPSTIQFVYNGELKPWVSGKDLILYTIGDIGVDGALYRAMEFTGETIENLSMDNRMTISNMAIEAGGKCGLIAPDEKTFKYLENRAQRDYTPCYSDDDAEYEKVIEYDVSDIEPQVAFPHLPENTRPISEEGDIKIDQAVIGSCTNGRMEDLRIAAGILKEKQVHHDVRCIVIPGTQDIYKQALKEGLIEIFIEAGAAVSTPTCGPCLGGHMGILARGEKAIATTNRNFVGRMGHPESEVYLANPAVAAASAIKGYIAHPEEVL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: FEDG_AMYME
Sequence: MRITVNVDGTSYTDEVEPRTLLVH
What are the official names of this protein?
Formate ester dehydrogenase gamma chain, FEDH.
Protein: EMTA_ECO8A
Sequence: MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SCX4_BUTOM
Sequence: GRDAYIAQPENCVYECAKNSYCNDLCTKNGAKSGYCQWLGKYGNACWCEDLPDNVPIRIPGKCHF
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This alpha-like toxin is highly toxic to mice and insects.
What are the official names of this protein?
Alpha-like toxin Bom4, Bom IV, BomIV.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: WAPA_HOPST
Sequence: MSSGGLLLLLGLLTLWAELIPVSGQDHPKKPGLCPPRPQKPPCVRECKNDWSCPGEQKCCRYGCIFECRDPIFVK
What is the function of this protein?
Damages membranes of susceptible bacteria.  Has no hemolytic activity.  Not toxic to mice.  Does not inhibit the proteinases elastase and cathepsin G.
What are the official names of this protein?
Stewaprin-a.
What is the protein family that this protein belongs to?
Belongs to the snake waprin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMD_CHLL3
Sequence: MMDGIRIDVLSVIPGFFDSVLDNGLLAIARKKGYADIVVHNLHDYGLGRYRQVDDSPFGGGAGMVLRPEPVFACVEKLQSERCYDAVIFPTPDARPFLQGDANRLSRMKNLMFLCGHYKALDERVRQSLVTMEYSIGDVVLSGGEIPSLLMMDALLRVVPGVLGDSESALTDSFQTGMLDCAYYTRPPEFRGMKVPEVLLSGHHAKIEQWRQENALERTRRLRPDLLGEDVE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAHE_PSEAI
Sequence: MSNKIMKTSRLTAEDINGAWTIMPTPSTPDASDWRSTATVDLEETARIVEELIAAGVNGILSMGTFGECATLTWDEKRDYVSTIVETIRGRVPYFCGTTALNTREVIRQTRELIDIGANGTMLGVPMWVKMDLPTAVQFYRDVADAVPEAAIAIYANPEAFKFDFPRPFWAEMSKIPQVVTAKYLGIGMLDLDLRLAPNIRFLPHEDDYYAAARINPERITAFWSSGAMCGPATAIMLRDEVVRAKSTGDWAKAKAISDDMRAADSTLFPRGDFSEFSKYNIGLEKARMDAAGWLKAGPCRPPYNLVPEDYLAGAQKSGKAWAALHAKYSNELK
What is the function of this protein?
Involved in the naphthalene upper catabolic pathway.  Catalyzes the transformation of trans-O-hydroxybenzylidenepyruvate (THBPA) to salicylaldehyde and pyruvate.  The reaction is reversible (By similarity).
What are the official names of this protein?
Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase, THBPA hydratase-aldolase, 2'-hydroxybenzalpyruvate aldolase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: LGRA_BREPA
Sequence: MRILFLTTFMSKGNKVVRYLESLHHEVVICQEKVHAQSANLQEIDWIVSYAYGYILDKEIVSRFRGRIINLHPSLLPWNKGRDPVFWSVWDETPKGVTIHLIDEHVDTGDILVQEEIAFADEDTLLDCYNKANQAIEELFIREWENIVHGRIAPYRQTAGGTLHFKADRDFYKNLNMTTVRELLALKRLCAEPKRGEKPIDKTFHQLFEQQVEMTPDHVAVVDRGQSLTYKQLNERANQLAHHLRGKGVKPDDQVAIMLDKSLDMIVSILAVMKAGGAYVPIDPDYPGERIAYMLADSSAAILLTNALHEEKANGACDIIDVHDPDSYSENTNNLPHVNRPDDLVYVMYTSGSTGLAKGVMIEHHNLVNFCEWYRPYFGVTPADKALVYSSFSFDGSALDIFTHLLAGAALHIVPSERKYDLDALNDYCNQEGITISYLPTGAAEQFMQMDNQSFRVVITGGDVLKKIERNGTYKLYNGYGPTECTIMVTMFEVDKPYANIPIGKPIDRTRILILDEALALQPIGVAGELFIVGEGLGRGYLNRPELTAEKFIVHPQTGERMYRTGDRARFLPDGNIEFLGRLDNLVKIRGYRIEPGEIEPFLMNHPLIELTTVLAKEQADGRKYLVGYYVAPEEIPHGELREWLGNDLPDYMIPTYFVHMKAFPLTANGKVDRRALPDVQADAELLGEDYVAPTDELEQQLAQVWSHVLGIPQMGIDDHFLERGGDSIKVMQLIHQLKNIGLSLRYDQLFTHPTIRQLKRLLTEQKQVSLEPLRELDEQAEYETSAVEKRMYIIQQQDVESIAYNVVYTINFPLTVDTEQIRVALEQLVLRHEGLRSTYHMRGDEIVKRIVPRAELSFVRQTGEEESVQSLLAEQIKPFDLAKAPLLRAGVIETADKKVLWFDSHHILLDGLSKSILARELQALLGQQVLSPVEKTYKSFARWQNEWFASDEYEQQIAYWKTLLQGELPAVQLPTKKRPPQLTFDGAIQMYRVNPEITRKLKATAAKHDLTLYMLMLTIVSIWLSKMNSDSNQVILGTVTDGRQHPDTRELLGMFVNTLPLLLSIDHEESFLHNLQQVKAKLLPALQNQYVPFDKILEAARVKREGNRHPLFDVMFMMQGAPETELESNMHHINAGISKFDLTLEVLERENGLNIVFEYNTHLFDEGMILRMVAQFEHLLLQAVHGLDQQVKRFELVTEDEKRDLFLRVNDTAKAYPNKLIMSMLEDWAAATPDKTALVFREQRVTYRELNERVNQLAHTLREKGVQPDDLVMLMAERSVEMMVAIFAVLKAGGAYLPIDPHSPAERIAYIFADSGAKLVLAQSPFVEKASMAEVVLDLNSASSYAADTSNPPLVNQPGDLVYVMYTSGSTGKPKGVMIEHGALLNVLHGMQDEYPLLQDDAFLLKTTYIFDISVAEIFGWVPGRGKLVILEPEAEKNPKAIWQAVVGAGITHINFVPSMLIPFVEYLEGRTEANRLRYILACGEAMPDELVPKVYEVLPEVKLENIYGPTEATIYASRYSLAKGSQESPVPIGKPLPNYRMYIINRHGQLQPIGVPGELCIAGASLARGYLNNPALTEEKFTPHPLEKGERIYRTGDLARYREDGNIEYLGRMDHQVKIRGYRIELDEIRSKLIQEETIQDAVVVARNDQNGQAYLCAYLLSEQEWTVGQLRELLRRELPEYMIPAHFVLLKQFPLTANGKLDRKALPEPDGSVKAEAEYAAPRTELEATLAHIWGEVLGIERIGIRDNFFELGGDSIKGLQIASRLQRINWTMVINHLFLYPTIEQIAPFVTSEQVVIEQGLVEGLVKLTPIQRDFFERITADRHHWNQARMLFCRDGLEREWVVETLNALVLQHDALRMRFRETEQGIVQFHQGNEGKLFGFHVFDCTEELDIAKKVEEQANVLQSGMNLQEGPLVQAALFMTRTGDHLLLAIHQLVVDEASWRIILEDFQTAYKQKAAGEPIALPNKTHSYQSWAEELHNAANSKKLTSELGYWRKIASSPTRPLPQDQEPLSRTEQSTATAAIRFAKAETANLLHEANHAYQTEAQELLLAALGMALRDWTRADDVTVFLEKDGRESAAKGLDVSRTVGWFHSLFPVVLSAARSGDPGEQIKQVKEMLRAIPHQGSGYSILKQLTDLRHKHPDDFTLQPKIVVHAWEQLDAGLETDWLTLSHLPQGSVRGANAERMQQLDVFSKISNGELTIHIQYHRDEYRKATIDKLLELYQAHLNALLAHCLQKTETELTPSDFVDKNLSRSELDDIMDLISDL
What is the function of this protein?
Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis.  This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide.
What are the official names of this protein?
Linear gramicidin synthase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: GLYA_CITBB
Sequence: MSVLETFDPAVAEVIRQETERQEYNLELIASENFVSPAVLEAQGSVLTNKYAEGYPGKRYYGGCHCVDVVENLAIDRAKELFGADHVNVQPHSGSQANMAVYFSVLKPGDTVLGMNLAHGGHLTHGSPVNFSGKLFNIVPYGVSKETQTIDYEETERLALEHKPKMIVVGASAYPRIIDFEAFRRIADKVGAVVMVDMAHIAGLVAAGLHPSPVPYAEFVTTTTHKTLRGPRGGMIMCREDWAKTLNSNIFPGIQGGPLMHVIAAKAVAFKEALTPEFKQYQGQIVKNAKALAEGLTKRGFKLTSGGTDNHLMLVDLSQTELTGKVAEEALDRAGITVNKNGIPFDTRSPFITSGIRIGTPAATSHGLKEAEMEQVAGFIAEVLGNVSDEAKLAAVKTQVNALMKRFPMYANRLV
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FYV7_KLULA
Sequence: MAKVEKKKFTKEYRLKEIQRNLTKKARLKKEYLKVLKDEGYSIPEKPQYEKHDRSSVEAKKALNKQKVRDQREEHKLRKRTQKEKEQSFKEQEMKRIQLSKEKQVERDRRAKKLTQRTKRGQPVMGPKINDLLDKINSDETYTR
What is the function of this protein?
Involved in the processing of the 20S pre-rRNA.
What are the official names of this protein?
rRNA-processing protein FYV7.
What is the protein family that this protein belongs to?
Belongs to the FYV7 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ACCD_ACIB5
Sequence: MNQEVKSGKVLSPSTPWTQRPVPGIEVADEQQTLKATFTEPTIECPECHALVTRTAISFNAYVCPQCDEHLRMKARDRLNWFFDNVVAELGQEFSAKDPLKFVDSKPYPDRMREAQTKTGETEALIAMQGNLNGVDMIACAFEFDFMGGSMGTVVGDRFVKAAELAIEKRQPLICFAASGGARMQEGMLSLMQMARTSAAIQKLKDAGLPYIVVLTHPVYGGVTASLAMLGDIHIAEPKAMIGFAGKRVIEQTVRETLEEPFQRAEYLLDHGVVDQIVHRHALRDTVSRLVSKLMNLP
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_PHOPR
Sequence: MTLLALGINHNTASVDLREKVAFSPDKLKEALQQLESHPEVTSSIIVSTCNRTEVYCDVTHSGPGVMIDWLAKFHRLSAEEILPSLYFHEEQAAARHLMRVACGLDSLVLGEPQILGQVKQSYYSSQEYDAIHGTLEKLFHKTFTVAKRVRTETDIGGNAVSVAYAACTLAKQIFESLSDTTVLLVGAGETIELVSRHLVEQGCNKLIVANRTKERAANLAEEFGAEVIGLPEIPEHLHRADIVISSTASPLPIVGKGMVEKAIKARRHQPMLFVDIAVPRDVEAEVGDLNDVYLYTVDDLHSIIEKNREQRKVAAIQAEAIISEESAAFMSWLRSLEAVDSIRQYRCFADDIKNDMLSRSLQAIANGVAPEKVLVELSNKLTNKLIHAPTRAMQQAAHNGEPEKLSVIRETLGLDSIKD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: NTPPA_CLOBM
Sequence: MKNIILASASERRQELLKRILEDFQIIVSDFDESSIPFKDNIPSYVMNLAEGKARSVGKKIMDQDSNLVIGCDTLVAFNNKVLGKPKDKKDAFEMLQALSGNEHEVYSGLAILDVKSNKIITDFVCTKVKFSKLTSLQIEKYINTGDPMDKAGAYGIQGKAGVFVENINGCYYNVVGLPLNKLNSMLMEMGVNL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMN6_SHESW
Sequence: MAFTFKQFHIDDLNCGMAVSTDAVVLGAWAPLTNAKQILDIGAGSGILGLMAAQRSQANITCIELDDTAAIACQHNIAQSPWASRIRLVQGSIQQLSQAEEYQGYFDHIICNPPYFEHGPQAQLSQRAMARHTDQLSFNELLAAIEQCLSPNGLASLILPIQSLHNFNHLLSQSRLEWVERVDIKSVEGKRANRVLCLLTAQTHRTVEPKVSELTLRDTSGQYSQAMVHLTQDFYLKL
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_STAAE
Sequence: MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVIIDYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGGGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVADEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMVMITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHNDNNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKMYGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGEKITSNAATELPLTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_CHLPD
Sequence: MPLHKSAEKRLRQSEKRNVRNRARKKELKVLLKNMQKLIDTSADKNVVEEAYRSAVQKLDRLGVKRYLHPNKASRKKAQLTKMLNNYVKVD
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: UBIE_AGRRK
Sequence: MAESRTSADGGMETSYGFREVADGEKQGLVNEVFHKVAKRYDIMNDVMSMGLHRAWKDAMISALNPRKDPSYKVLDVAGGTGDIAFRIVEASNRLAHATVLDINGSMLGVGAERAAKKKLTDNLTFVEANAEELPFEPNSFDAYTIAFGIRNVPRIDVALKEAYRVLKRGGRLLVLEFSEVDLPLLDRVYEAWSFNAIPQFGKAITGDAEPYQYLVESIRKFPNQQDFATMIREAGFSRVNFTNYTGGIAALHSGWKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: AZOR_AGRFC
Sequence: MSNILLITSSPRGDESVSNKFAGELAGKLKAKSASNTLVHRDLAADPIPHLDTVKTAAIRKPADQRTAEESVAADYSDKLVTELLAADTVVIGTGLINFNIYSGLKSWIDNVARAGQTFKYTETGPVGLATGKKVYIVLAAAGVYSEGPAVSMNHAVPYLKTVLGFMGMTDVEVIYVEGLAFGPEAVEKAVAAAEAKVEELAQAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RS15_SALTO
Sequence: MALDQQAKAKIRAEYATVEGDTGSPEVQVAVLTKRIADLTEHLKVHKHDHHSRRGLLLLVGRRRRLLNYVQKKDINRYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: UDB37_RAT
Sequence: MPGKWIFALLLLQISFCLRSAKCGKVLVWPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPKKSPDLKFETFPTSVSKDELEKYFIKLADAWTYELQRDTCLSFSPLLQNMMDEFSDYYLSVCKDAVSNKQLMAKLQESKFDVLLSDPVAACGELIAEVLHIPFLYSLRASPGHKIEKSSGRFILPPSYVPVILSGLGGQMTFIDRVKNMICMLYFDFWFHMFNAKNWDPFYTEILGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCKPAKPLPKDIEDFVQSSGEHGVVVFSLGSMVSSMTEEKANAIAWALAQIPQKVLWKFDGKIPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEVINNPFYKKNAMWLSTIHHDQPMKPLDKAIFWIEYVMRHKRAKHLRPLGHNLPWYQYHSLDVIGFLLACLAVIAALAVKCFLFIYRFFAKKQKKMKNE
What is the function of this protein?
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.  About 30-fold less active than Ugt2b17 toward testosterone and dihydrotestosterone.
What are the official names of this protein?
UDP-glucuronosyltransferase 2B37, UDPGT 2B37, 17-beta-hydroxysteroid-specific UDPGT, UDP-glucuronosyltransferase R-21, UDPGTr-21, UDPGTr-5.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: UL130_HCMVM
Sequence: MLRLLLRHHFHCLLLCAVWATPCLASPWSTLTANQNPSPPWSKLTYSKPHDAATFYCPFLYPSPPRSPLQFSGFQRVSTGPECRNETLYLLYNREGQTLVERSSTWVKKVIWYLSGRNQTILQRMPRTASKPSDGNVQISVEDAKIFGAHMVPKQTKLLRFVVNDGTRYQMCVMKLESWAHVFRDYSVSFQVRLTFTEANNQTYTFCTHPNLIV
What is the function of this protein?
Plays a role in viral entry into host cells.  Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131.  This complex is required for entry in epithelial, endothelial and myeloid host cells (PubMed:23853586, PubMed:28783665, PubMed:17942555).  Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection (PubMed:30057110).
What are the official names of this protein?
Envelope glycoprotein UL130.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 UL130 protein family.
What are the subcellular locations of this protein?
Virion membrane. Note=Found as a pentameric complex at the surface of virion envelope.