PharMolix/UniProtQA huggingface dataset:
Protein: GATB_LEIXX
Sequence: MAKVDLMEYERALELFEPVLGFEVHVELNTKTKMFCGCANEFGSGANTNTCPTCLGLPGGLPHVNEKAIESSIRLGLALGCDIAESSRFARKNYFYPDLAKNFQTSQYDEPIAHDGRVSIELENGRELTIEIERAHMEEDAGKLTHIGGATGRIQGADHSLVDFNRGGVPLVEIVTKMIEGAETDAPEVGRTYVRAIRDIVKALGVSNARMEEGNVRCDANVSLRRRGSSELGTRTETKNVNSLRSIERAVRYEIQRQAAILEAGGAIVQETRHWHEDTGSTSAGRPKSDADDYRYFPEPDLVPVAPSREWIEELRGTLPEPPAARRKRLTAEWGFTALEFQDVANADLLDELEATIAAGAAPAAARKWWTGEIARVANAQGVAAGTLVAPEHVAELAGLVEAGTLTDRLARQVLEGVIAGEGRPQEVVDARGLAVVSDDGALVAAIDEALAAQPDVLAKIRDGKVQAAGAVIGAVMKAMKGQADAARVRELVLERASQ
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: LLDD_CAUVC
Sequence: MIVSSTTDFREAARRRLPRFLFDYIDGGAYAERTMARNIDDLADIALRQRVLMDVSVVDPSTTLFGVRQALPVALAPVGLTGMYARRGECQAARAAAAKGVPFCLSTVSVCDVDEVRAASATPFWFQLYVLRDRGFMRDLLARASAAGATTLVFTVDMPVPGARYRDAHSGMSGPNAAARRLVQAALKPAWAWDVGVMGHPHRLGNVAPALGKASGLQDFMGWLAANFDPSIQWSDLKWIRDAWKGPLVIKGVLDPEDAKAAADIGADGVVVSNHGGRQLDGVLSSARALPAIADAVGDRLTVLADGGVRSGLDVVRMLALGARGVLIGRAYAYALAARGEAGVTQLLDLIDKEMRVAMALTGVRDVASINETILAERVPRAG
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DNAJ_ALCBS
Sequence: MSKRDYYEVLGAAKDASAQDLKKAYRRLAMKYHPDRNPDDKEALAKFKEAKEAYEVLADEQKRAAYDQFGHAGVNGQGGGPGAGAGAGGFGDIFGDIFGDIFGGAGGGGGRRGPSRGADLRYTLELSLEQAVRGCDEKIRIPTWDSCDVCHGSGAKEGSQPVTCTTCGGVGQVRMQQGFFTVQQACPTCKGEGKIIKDPCGNCGGQGRVQNTKTLSVKIPAGVDTGDRIRLAGEGEAGVHGAPSGDLYVQVAVREHDIFQRDGDNLYCEVPISFVDATLGGELDVPTLNGKVKLKVPAETQSGKLFRLRGKGVAPVRGGAPGDLLCKVVIETPVKLSSEQKELLRKFQESLESGGNRHNPRKNNWFEGVKRFFDTK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_CLOBA
Sequence: MKKAIMGKKIGMTQIFNEAGKVIPVTVVEAGPCVVVQKKTVEKDGYEAIQVGFGDIREKLVNKPAKGHFEKAGVVLKRTLKEFRLEDVSQYEVGQEIKADVFEIGDKIDVSGVSKGKGFQGVIKRWNQQRGPMTHGSKFKRAPGSMGASSDPSRTFKNKRMPGHMGCVNTTVMNLEVVKVIAEKNLLLIKGGIPGPNKGTVVIRNAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SECA_CITBB
Sequence: MFGALIKKLVGSKNERELKRMWPIVERINQLEPELVKLSDEALRGKTAQFKERYSRGESLDSMLPEAFAVCREAGKRVLGMRHFDVQLIGGMVLHSGKIAEMKTGEGKTLVATLPSYLNGISGKGVHVVTVNDYLAKRDSDWMGRIHKFLGLSVGVIVHGLEDHERREAYAADITYGTNNEFGFDYLRDNMKFDLDEYVQRPFNFAVVDEVDSILIDEARTPLIISGPTEDSTDKYYIIDRIIPLLKRGEVIEVEANTLSGKRKTYTGDFTVDEKAKSATLTEEGVLKVEKLLKIENLYDPRNMEVLHHTQQALRAHALFKRDVDYVVRDNEVIIVDEFTGRLMPGRRWSDGLHQAIEAKEGAKIENENQTLATITFQNYFRMYERLSGMTGTADTEAEEFHKIYKLDVVVIPTNRPLLRPDFPDVIYKTEREKFNAVIGEIKELHEKGQPILVGTISIEKSEELSELLKRQSIPHFVLNAKQHEKEAEIVAQAGRKGMVTIATNMAGRGTDILLGGNPDGLARQEFKGTPEARTEEFMAAFMETLSKDLPEKELLQSLEREYPGIMPVVASCLKQEGEIDLEELEQQVLAEHQKQFNLLVEKNKPVCAVEHDEVVALGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLQDDLLRIFGSERVSMIMDKLGIEEGEAITHGLITRAIENAQKKVEAHNFEIRKHLIEYDDVMNKQREVIYTQRKEILAGNEIRDSFTGMMEETVGDIVSAYVIDRTPAREWDWQGITDSVQKVFGFHLDLTPDLMDRITPVNFEETLRTTARERFQQRLTEFGDDLMDHLIKVIMLQVIDAQWKDHLLSIDHLKEGIGLRGYGQKDPKQEYKREAYKLFMDMMLRIREEVVEKIFWVQVGSEEEMEQFELEQPQQRMVFNLVDEEAASAPAQMPSKSKRSAGRNDPCPCGSGQKYKKCCGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PTH_METKA
Sequence: MYKQVIVVRGDLKLSRGKLAAQVAHASLGAFLRAKESGAPVEEWLREGQKKVVLKCKDKEELLELHELAKRRGLPSFLVRDAGLTELEPGTVTCLGIGPEREEEIDRVTGDLPLLR
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_CERS1
Sequence: MAKHSDPNSKLIAENRRARFDYFIEEEIEAGIMLLGSEVKSLRQGGSNIGESYASVEEGELWLINGYIAPYLQAKTWGHEERRKRKLLVSRRELARLWTATAREGMTIVPIRMYFNDRGIVKLKIGIAKGKKLSDKRETSAKRDWSREKQRLLKQNS
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: CINAL_LEPIN
Sequence: MFSPKIIILSTGSELTSGRSQDTNSSWIANELFGIGFTVSKLVVLPDDPEAILEELRTLVSLATKKNPVLLIMTGGLGPTEDDYTLEVVCKLKGVSSVESVVARQRIEAFYKLRGKNFQESLQTAIRQISVPKDSTILNNEVGIAPGFIVSLGENAHLGCMPGVPGEMTEMFREEFSTWILKKYSTRELHSGFRFIWWMSESQFQKEFISKEESVTSEKVIWGVAAKRGYIRVSFQSNERALVDFLLKKLDEIYGPKSTLDVFEELPKLLIEKKITVGTAESCTGGLISKIFTDKPGSSTYFYGGVISYDNGVKEGILGVKKNTLKEFGAVSMETAKEMAEGALVALGVDYSISVTGIAGPGGGTPQKKVGLVYFGIGQKNEKTETHEHYFPFPRSSFREFAAHTGIYLLYNRLKRLA
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: MIAA_RHIE6
Sequence: MENLLSVENAILITGPTASGKSALAVELAKRYGGAVVNADSMQVYDTLRVLTARPSEEEMQGVPHHLYGHVPAGAAYSTGAWLRDVSALLPALKAAGQLPVFVGGTGLYFKALTGGLSDMPEIPEGLREELRMRLVAEGPEGLHAELEAIDPAMSASLNRQDGQRIVRALEVIKATGRSIAEFHRRLGPVLIDADEARKIVVLPDRAVLHARINGRFEKMLQQGAESEVRALLALGLPAVAPVMKAIGVSQITAMLKGEMTREEVLEKGAAATRQYAKRQMTWFRNQMDESWERLAP
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: EX7S_ERWT9
Sequence: MPKKTQQSVSFEASLQQLEQIVSRLESGDLALEEALNEFERGVQLARAGQQVLQQAEQRVQILLSDDKNAELTPFTPEKE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHE_PSEAE
Sequence: MADETELKRLYWHSRRGMLELDVLLVPFVQEVYPGLDAEDQARFRKLLECEDQDMFGWFMQRGEPEDADLRRMVRMILDRVQPD
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP_RHIEC
Sequence: MENRTNFFHLHLISDSTGETLISAGRAASAQFRSAQPIEHVYPLIRNRKQLLPVLQAIDDAPGIVLYTIVDRELANLIDERCVEMGVASVNVLEPVMNAFQIYLGAPSRRRVGAQHVMNAGYFARIEALNFTMDHDDGQMPDDYNDADVVIIGISRTSKTPTSIYLANRGIKTANIPIVYGVPLPESLLAATKPLIVCLIATTDRISQVRENRVLGTTQGFDREHYTDRATISEELKYARSLCARHGWPLIDVTRRSIEETAAAIVALRPKLR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: ACP_ALKCK
Sequence: MADVMERVTKIIVDRLGVEESEVKLESSFKEDLKADSLDVVELVMELEDEFDMEIADEDAEKIATVKDVVDYINNNQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_JANSC
Sequence: MTKKIAILGASGYTGAELCRLIAGHPDMTIVALTGDRKAGQPMASVYPFLRGAGLPDLVRIEDVDFSGVDLAFCALPHATSQSVIKALPADLKVVDLSADFRLRDPADYAKWYGKDHDAPALQKQAIYGLTEFYRDQIRDARLVAGTGCNAATGQFALRPLIENGVVDLDDIIIDLICGVSGAGRALKENLLHAELSEGTHAYALGGTHRHLGEFDQEFSKVAGRKVEVQFTPHLAPFNRGILATCYVKGDAQAIHATLTAAYRGEMFIEVLPFGAAPSTHDVRGTNYCHIGVVADRRSGRAQIVAALDNLCKGSSGQAVQNANLMLGLEETAGLLGLGVFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP5G_DESAP
Sequence: MEVTDVRIRKVLDGGKMKAIVSVTLDDAFVVHDIKIVEGQNGLFVAMPSRRTPNGEFRDIAHPINASARARIQNAVLEAYEHRDAAEF
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: Y8590_DICDI
Sequence: MATYCLSPLMHLDHFFNKILLMTTTTTTHRKKYINFQEQKLKKQESIGQSQPDVQEQLQHQQLQHHQKLYKIN
What are the official names of this protein?
Putative uncharacterized protein DDB_G0284229.
Protein: ISPH_PSEF5
Sequence: MQIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVEDLRNRGAIFVEELDQVPDDVIVIFSAHGVSQAVRSEAAGRGLKVFDATCPLVTKVHIEVARYSRDGRECILIGHAGHPEVEGTMGQYDASNGGAIYLVEDEKDVAELQVRNPERLAFVTQTTLSMDDTSRVIDALRTRFPAIGGPRKDDICYATQNRQDAVKQLADECDVVLVVGSPNSSNSNRLRELAERMATPAYLIDGAEDLQRSWFDGVERIGITAGASAPEVLVRGVIQQLQAWGATGADELAGREENITFSMPKELRVRSLL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: CH60_RICRI
Sequence: MATKLIKHGSKAREQMLEGIDILADAVKVTLGPKGRNVLIEQSFGSPKITKDGVTVAKSIELKDKIRNAGAQLLKSAATKAAEVAGDGTTTATVLARALAREGNKLVAAGYNPMDLKRGMDLAVNAVVEEIKKSSKKINSQEEIAQVGTISSNGDKEIGEKIAKAMEEVGKEGVITVEEAKNFSFDVEVVKGMMFDRGYLSPYFVTNSEKMVAELENPFILLFEKKLSNLQPMLPILEAVVQSQRPLLIIAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMMEDIAILTKGELITEDLGMKLENVSIKSLGTAKRVTISKENTVIVDGNGDKKNIEDRVLQIKSQIAETTSDYDKEKLQERLAKLSGGVAVLKVGGATEVEVKERKDRVEDALAATRAAVE
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_CAMC5
Sequence: MYVLFEGVDGVGKSTQIEMIARAHEDSLVTKEPGGTKIGQKLREILLGGDFKLSARAEILLFLADRAEHYQKMIKPNSSRLILSDRGFVSGVAYALANDASLKIDDLLWLNSFALEGKFADKIVFFEASETLIKKRLSSRGLIDAIEARGLKYLLKVQECMKEVLKAHKFNVLYIDASEDIATINAKIENFIKF
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: GARS_PONAB
Sequence: MPSLRPVLFRGARAALLLLLPPRLLARPSLLLRRPLSAPSCAPISLPAAASRSSVDGAGAEEVLAPLRLAVRQQGDLVRKLKEDKAPQVDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPNKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETEGKTFQLTKDMVNVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEVSELPSIVRDLANGNITWADVEARYPLFEGQETGKKETIEE
What is the function of this protein?
Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP).  Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.  Thereby, may play a special role in Ap4A homeostasis.
What are the official names of this protein?
Glycine--tRNA ligase, Diadenosine tetraphosphate synthetase, Ap4A synthetase, Glycyl-tRNA synthetase, GlyRS, Glycyl-tRNA synthetase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Cell projection, axon. Secreted. Secreted, extracellular exosome. Note=Secreted by motor neuron, possibly through the exosome pathway (By similarity).
Protein: CYB_DELKE
Sequence: MKILRKTHPLLKIVNHSFIDLPTPSNISSWWNFGSLLGMCLVIQILTGLFLAMHYTSDTATAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYVLSETWNIGIILLLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDLLGIFLLLMTLMILALFFPDILGDPDNFTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILATFPLLNTSKQHGLIFRPITQTIYWIFIANLLVLTWIGGQPVEYPFTTIGQIASITYFTIIVIIMPVSNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARCA_HAEIN
Sequence: MTTPKILVVEDEIVTRNTLKGIFEAEGYDVFEAENGVEMHHILANHNINLVVMDINLPGKNGLLLARELREELSLPLIFLTGRDNEVDKILGLEIGADDYLTKPFNPRELTIRARNLLHRAMPHQEKENTFGREFYRFNGWKLDLNSHSLITPEGQEFKLPRSEFRAMLHFCENPGKLQTREELLKKMTGRELKPQDRTVDVTIRRIRKHFEDHPNTPNIIMTIHGEGYRFCGDIE
What is the function of this protein?
Member of the two-component regulatory system ArcB/ArcA.  Represses a wide variety of aerobic enzymes under anaerobic conditions (By similarity).
What are the official names of this protein?
Aerobic respiration control protein ArcA homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_PARUW
Sequence: MNFEIEQILTQIIAFLIMLGVLKKFVWKRLLNLIEERKQLIQSEFDKIENQKEEVTKLSEEYKAKLHDIDAEARRRIQEAVVKGRDIAHDIEQETRQKVTSLLNNAQEEMKLELAQAKEQLKKDVINISFAITEKLIHEKVDISKHQKLVEEAVEQVEIR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LPT_ECOK1
Sequence: MKRISTTITTTITITTGNGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: CYF_AETCO
Sequence: MQTRNTFSWTWIREEITRSISVSLMIYIITWSSISNAYPIFAQQNYENPREATGRIVCANCHLANKPVDIEVPQAVLPDTVFEAVVKIPYDMQLKQVLANGKKGALNVGAVLILPEGFELAPPDRISPEMKEKIGNLSFQNYRPNKKNILVIGPVPGQKYSEITFPILAPDPATNKDVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNATAGGIISKILRKEKGGYEITIADASNGRQVIDIIPRGLELLVSEGESIKLDQPLTSNPNVGGFGQGDAEIVLQDPLRVQGLLFFLGSVVLAQIFLVLKKKQFEKVQLSEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: BEST2_MOUSE
Sequence: MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGLYMALSAAYRFLLAEEQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVHRWWNQYLCMPLPDALMCIVAGTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSSLAAQARREGRIRDNSALKLLLEELNVFRSKCGMLFHYDWISIPLVYTQVVTIAVYSYFLACLIGRQFLDPAQGYKDHTLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAMLEKDLYWDAAEARAPYTAATAFLLQQPSFQGSTFDIALAKEDMQFQRLDGVDGPLGEVHGDFLQRLLPAGAGSVGPLGRRLSLLRRKNSCVSEASTAASCGCAGAADGGGVECGCGDPLLDPSLREPELEPPACPEPPAPIPGPTPEPFTTVSIPGPRAPAPPWLPSPIGEEEESPA
What is the function of this protein?
Forms calcium-sensitive chloride channels.  Permeable to bicarbonate.
What are the official names of this protein?
Bestrophin-2, Vitelliform macular dystrophy 2-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CD4_CERAT
Sequence: VVLGKKGDTVELACNASQKKSTQFHWKNSKQIKILGNQGSFLTKGSSKLSDRADSRKSLWDQGCFSMIIKNLKIEDSETYICEVENKKEEVELLVFGLTANSDTHLLEGQSLTLTLESPPGSSPSVKCRSPRGKNIQGGRTLSVPQLERQDSGTWTCTVSQDQKTVEFKIDIVVLAFQKASSTVYKKEGEQVEFSFPLAFTLEELTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLALEAKTEKLHQEVNLVVMRATQFQENLTCEVWGPTSPKLTLSLRLENKKATVSKQAKAVWVLNPEAGMWQCLLSDSGQALLESNIKVVPTWPTPVQPMALIVLGGVAGLLLFTGLGIFFCVRCRH
What is the function of this protein?
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses.  In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex.  The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins.  Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs).  In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.  LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells.  In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway.  Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.
What are the official names of this protein?
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts.