PharMolix/UniProtQA huggingface dataset:
Protein: PURQ_BACC2
Sequence: MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVENNETMFTSQYEKNEIINIPIAHGEGNYYCDEETLKQLEENNQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_STUST
Sequence: MATVDRWLLPDGIEEVLPPEAARIETARRRVLDLFQRWGYELVITPHVEFLESLLSGSGQDLDLKTFKVIDPLSGRQMGLRADITPQVARVDAHTLRREGPSRLCYAGSVLHAKPRALATSRSPIQLGAELYGDSSTSSDIEVISLMLEMLELAMVPDVHMDLGHVGIYRGLARAAGLSGEAEQRLFDAMQRKAMDEIAELTATVEPSLAAMLQALARLCGGRETLDAARRVLAEAPAPVTEALEALIRIADQLALRYPDLPLYFDLGELRGYHYHTGVVFAVFVPGVGQSIAQGGRYDDIGADFGRARPATGFSTDLKTLVSLGKAELDSRLSGIWAPYGDDTALWQQISRLRREGERVVQALDGQNGETAATAGCDRQLILQDETWTVAPLAS
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
Protein: UVRB_GEOSL
Sequence: MERFRLASDYEPRGDQPRAIAELSEGIVRGDRDQVLLGVTGSGKTFTMANVIAAVNRPALVLAPNKTLAAQLYGEFRELFPDNAVEYFVSYYDYYQPEAYIPTTDTFIEKDSSINDEIDKLRHAATRSLLTRRDVIIVASVSCIYGIGSPAEYQAMHIFFHQGDEYGRDELLRKLVDIQYERNDLDFHRGTFRVRGDIVEIFPAHEGERAYRIEFFGDTVDAISEIDPLRGVVVQRLTKCAVYPASHYVATRETLDRAMEEIRTDLRERLQWFRERNMLVEAQRLEQRTMFDLEMMEEMGFCQGIENYSRYFDGRTPGEPPYTLLDYFPRDFILFVDESHITVSQVGGMYRGDRSRKETLVNYGFRLPAALDNRPLTFGEFTERLNQSVYVSATPADYELQQSGGVVVEQVIRPTGLLDPVIEVRPATEQVDDLLHEVRETTARGERVLVTTLTKRMAEDLTDYYRDLGVRVRYLHSDIDTIQRMQIIRDLRMGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSARSLIQTCGRAARNVNGRVIMYADTVTGSMQSCLDETARRRALQEAFNTEHGITPQTVKKGLRTILESIEERDYYTVAAVAETREEYISADEIPKRVKKLRKEMLDAAKKLEFERAADLRDQIKKLEEMELRLR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_PSYA2
Sequence: MRKDIHPNYQEVLFHDTNADVFFLTRSTVKTKTTREYEGSEYPYYPLDISSASHPFYTGEQRKTSTEGRVASFNKRFGAFGGRKKAADTDAAE
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: 2ABB_RAT
Sequence: MEEDIDTRKINNSFLRDHSYATEADIISTVEFNHTGELLATGDKGGRVVIFQREQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVKLWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYIMTRDYLTAKVWDLNMENRPVETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSVIMTGSYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRRKDEISVDSLDFSKKILHTAWHPSENIIAVAATNNLYIFQDKVN
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.  Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity.  Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform, PP2A subunit B isoform B55-beta, PP2A subunit B isoform BRB, PP2A subunit B isoform PR55-beta, PP2A subunit B isoform R2-beta, PP2A subunit B isoform beta.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Membrane. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Mitochondrion. Mitochondrion outer membrane. Note=Under basal conditions, localizes to both cytosolic and mitochondrial compartments. Relocalizes from the cytosolic to the mitochondrial compartment during apoptosis. Its targeting to the outer mitochondrial membrane (OMM) involves an association with import receptors of the TOM complex and is required to promote proapoptotic activity.
Protein: PDXB_ECO57
Sequence: MKILVDENMPYARDLFSRLGEVIAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLHERTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADCGDEGDFRSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y030_MYCTU
Sequence: MVSGSDSRSEPSQLSDRDLVESVLRDLSEAADKWEALVTQAETVTYSVDLGDVRAVANSDGRLLELTLHPGVMTGYAHGELADRVNLAITALRDEVEAENRARYGGRLQ
What are the official names of this protein?
Uncharacterized protein Rv0030.
Protein: STHA_YERPS
Sequence: MQQHFHFDAIVIGSGPGGEGAAMGLVKQGARVAVIERYNNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDNARTIKSSFADILNHADRVINQQTRMRQGFYDRNHCHMFSGDASFIDANTVNVRYADGTSDTLQADNIVIATGSRPYRPVNVDFNHERIYDSDTILQLSHEPQHVIIYGAGVIGCEYASIFRGLSVKVDLINTRDRLLAFLDQEMSDALSYHFWNNGVVIRHNEEFEQIEGTTDGVIVHLKSGKKVKADCLLYANGRTGNTSGLGLENIGLEADSRGLLKVNSMYQTALSHVYAVGDVIGYPSLASAAYDQGRIAAQAMIKGEANVHLIEDIPTGIYTIPEISSVGKTEQELTAMKVPYEVGRAQFKHLARAQIVGMDTGSLKILFHRETKQILGIHCFGERAAEIIHIGQAIMEQKGEGNTLEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDADA_ARATH
Sequence: MTEAMIRNKPGMASVKDMPLLQDGPPPGGFAPVRYARRISNTGPSAMAMFLAVSGAFAWGMYQVGQGNKIRRALKEEKYAARRTILPILQAEEDERFVSEWKKYLEYEADVMKDVPGWKVGENVYNSGRWMPPATGELRPDVW
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-A, Protein MATERNAL EFFECT EMBRYO ARREST 4.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA13 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: COAD_FRATO
Sequence: MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDIRIREQMIKEVFKDNQRVKVVSFQGLLVDTAVKHNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTPSEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYSKE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAO1_SHEPC
Sequence: MDDNKRPLYLPFAGPAILEAPLINKGSAFSEEERIFFNLEGLVPYAIETIEEQASRAYDQFRSFNNDLDKHIYLRNIQDTNETLFYRLVQNNISEMMPIIYTPTVGLACERFSKNYRRNRGLFISYPNKDRIDDILNNSTRQKVKIIVVTDGERILGLGDQGIGGMGIPIGKLSLYTSCGGISPAYTLPITLDVGTDNPQLLEDPMYMGWRHPRIGGEEYAEFIEAFMQAVHVRWPDTLIQFEDFAQKNAMPILERYKDRYCCFNDDIQGTAAVAVGCLLAACKAAGTELNQQRIAFLGAGSAGCGIAEAIVAQMVSEGISDEQARTQVCMVDRWGLLLDNMPNLLPFQQKLAQKCANIQNWNNFSDNISLLDVVNNAKPTVLIGVSGVPGLFTEEIIRAMHSHCARPIIFPMSNPTSRVEATPKDILHWTSGQALVATGSPFEPVVVDGETYEIAQCNNSFIFPGIGLGVLASGARHVSDAMLMASSRALAECSPLAIDGTGPLLPKLEDIHAVSKHIAFAVGKVAVEQGLTLPMSDEILQQSIEGNFWKPEYRRYKRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: RL31B_STAA1
Sequence: MKQGIHPEYHQVIFLDTTTNFKFLSGSTKTSSEMMEWEDGKEYPVIRLDISSDSHPFYTGRQKFAAADGRVERFNKKFGLKSNN
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: Y6531_BACAN
Sequence: MCKRFKFLLAVSALFISITVVLAGCGGSSVPYKKDDTYKDSKDNFITITAENEWRVKGSQNSEANYKVESTEYKGDSHSVVAISVKEKINGSDPLLVVNDYHYYILSPRENGFSLTPIGTSHPNSAQWKEFQEGFKGANDKEEFLKKEVANVNKQNIFKKTN
What are the official names of this protein?
Uncharacterized protein pXO2-32/BXB0031/GBAA_pXO2_0031.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MNMA_HAEI8
Sequence: MLISNTYNQHFPQLTQEQLARNATKKVICGMSGGVDSSVSAFILQQQGYQVEGLFMKNWEEDDDTDYCTAAADLADAQAVCDKLGIKLHKINFAAEYWDNVFEHFLTEYKAGRTPNPDILCNKEIKFKAFLEYAAEDLGADYIATGHYVRRAGDNENAKLLRGLDANKDQSYFLYTLSHKQVGQSLFPVGEIEKPIVRAIAEDLGLITAKKKDSTGICFIGERKFKDFLARYLPAQPGNIRTVDDEIIGRHDGLMYHTLGQRKGLGIGGLKNAGDEAWYVVDKDVENNELIVAQGHDHPRLFSKGLIASQLHWVDREPIRESLRCTVKTRYRQQDIPCVIEPIDDETIRVIFDEPQSAVTPGQSAVFYLGEVCLGGGIIAERI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF3_MALDO
Sequence: MSWQAYVDDHLMCDIDGNRLTAAAILGQDGSVWSQSASFPAFKPEEIAAILKDFDQPGTLAPTGLFLGGTKYMVIQGEPGAVIRGKKGSGGITIKKTSQALLIGIYDEPVTPGQCNIVVERLGDYLIEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-3, GD4-5, Pollen allergen Mal d 4.0101.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYI_LEPIC
Sequence: MSETQKENPYSSTVLLPKTDFPMKADLAKREPAQIQSWKSGQIFRKMKEQRKGKKEFVLHDGPPYANGNFHLGHSLNKIVKDIIIKSKSLAGFYADMIPGWDCHGLPIEVQVLKNLGKKARETGPEELRRLCRNYAEEFVGKQGEDLSRFLCFWEEDRIYKTMSPGFEAKIVEVFGELFQKGYVYRGKKPVYWSIDLATAHAEAEIEYYPHVSPSIYVKFPIVGEQKKFCLIWTTTPWTLPANLGICFNRKIEYSFFKTESGEELILADGLAESVTSTTGVSLNKVKSISSDELSVLKFQHPFMDRISISLFGDHVTLDAGTGCVHTAPGHGQDDYKVGLAAGLEPFSPVDDYGKYTDEFPLMQGKKVFDANPEIIQLLKDKGLLLHHSEFEHSYPHSWRSKKPLIFRATPQWFFKMDFNELREKSLSAIDGVQWIPSWGITRIRSMVETRPDWCLSRQRNWGVPIPAFTCESCGQTHIDDVSIQFFTKMVREKGIEIWYSEKAADLLPPGTKCGKCGSDSFKKGNDILDVWFDSGVSSFAVLGERKDEPPADLYFEGSDQHRGWFQSSLWPSMALRGIPPYKTVLTHGYVLDEKGHPMSKSLGNGIDPTADVIQIYGADILRLWVSSLDFRDDIKVGKESLKIVSEQYRKIRNTFRYLLGNLDGHTSEQNLPFEELEELDLFYLSKLSQFAEDVIANYEAYQFHQIYQKLILFCTVTLSQDYFDMIRDRMYCDARNSKTRKSSATALQYILETLCILTAPILSFTAEEVWVSNGKKDSVFLQNFPDLKFWKNQNLEEKFESVLQVREVVQKALEIARQENKLGKSLEAGLEIVSKNGTNLTKILPKETLEILFVVSQVHEKNPGLDVLSFYENEKFSVKVLKPVQVECPRCWRHTEDISKEGDLCGRCKSVVG
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y05_BPT7
Sequence: MYMLTIGLLTALGLAVGASFGKALGVAVGSYFTACIIIGIIKGALRK
What are the official names of this protein?
Protein 0.5, Gene product 0.5, Gp0.5.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: TREA_ECO7I
Sequence: MKSPTPSRPQKMALIPACIFLCFAALSVQAEETSVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYLWNDQQGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRASKMATATKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSATGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPLSESTTQPLKQKEAEPTP
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ATPF_DEHMB
Sequence: MEKLAELGINIPSFIAQIVNFGLLLGLLYLFAYKPILAKLDERSTRIKESMERTDQVKEQAQKAEEEFKKKIGEASQQGQLVIERAVKTGDEIRQKAIEEAKAEAEAMLSRARTEIRQERDEVVDQLRKEFAELTILAAGKVIDQSLDKKAHQALIDSVLENSTDLRKN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYDND_HELPS
Sequence: MRSHFCAEISEKDVGKTIKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKALEVRSEFVLVAKGKARLRGPGLENPKLKTGKIEIVLEELVIENKSATPPIEIGNKNVNEDLRLKYRYLDLRSLNAYEIFKLRSEVALIARNALAQKGFLEIETPILSKTTPEGARDYLVPSRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQPEFTQIDAEMSFCSENDVMGVVEDLLQEIFKAIGHNISKPFKRMPYKEAMENYGSDKPDLRFELPLIEVGDCFMDSSNAIFSNIAQDPKNKRIKALNVKGADAIFSRSVLKELEEFVCQFGAQGLAYLQIKEDGVKGPLVKFLSEKGLKNILEKTGAKTGDIVFFGAGDKKIVLDYMGRLRLKVAETLDLIDKDALNFLWVVNFPMFEKTENGYHAAHHPFTMPKNIECKDLEEIEAHAYDVVLNGVELGGGSIRIHKEEMQKKVFEKINIHEEEAQKKFGFLLEALKFGAPPHGGFAIGFDRLIMLMTKSSSIRDVIAFPKTQKASCLLTDAPSPINEEQLRELHIRLRK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_NITEU
Sequence: MNYPDIESPPAIFLMGPTASGKSAMALEIARRFPVEIIGVDSAQVYRFMDIGSAKPDKLILSEIPHHLIDLIDPDENYSAARFREDALSVMREITARGRVPLLVGGTMLYFKVLRQGLAALPPADDSVRRALEQQALDKGWPAMHAVLSQLDPVTAGRIQPNDSQRIQRALEVCYLTGKPMSEMLEQQQNADFPFRVFNIALLPGDRSVLHDRISQRFATMLEAGLIDEVRLIREQFHVNGDMPSMRCVGYRQVCMYLDNEISFARMQETGVFATRQLAKRQLTWLRSMSGLQIFDCLENRLARQIIDLIQAQRLFS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: Y195A_HAEIN
Sequence: MIRKLMKIPPFFTALFASAMFTLSVSQGVLAANSTNVLPTEQSLKADLANAQKMSEGEAKNRLLAELQTSIDLLQQIQAQQKINDALQTTLSHSESEIRKNNAEIQALKKQQETATSTDDNAQSQDYLQNSLTKLNDQLQDTQNALSTANAQLAGQSSISERAQAALTENVVRTQQINQQLANNDIGSTLRKQYQIDLQLIDLKNSYNQNLLKNNDQLSLLYQSRYNLLNLRLQVQQQNIIAIQEVINQKNLQQSQNQVEQAQQQQKTVQNDYIQKELDRNAQLGQYLLQQTEKANSLTQDELRMRNILDSLTQTQRTIDEQISALQGTLVLSRIIQQQKQKLPTNLNIQGLSKQIADLRVHIFDITQKRNELYDLDNYINKVESEDGKQFTEAERTQVKTLLTERRKMTSDLIKSLNNQLNLAISLELTQLQITQISDQIQSKLEQQSFWVKSNNPINLDWVKMLPRALIEQFNGMLKKLGFPTNYDNLPYLLMYFLGLFIVGGAIFKFKNRIKQQLNKINREIHRLDTDSQWSTPLALLLTAFLTLSSTLWFLAVCQMIGFFFFKNPEEFWHWSFSMAGYWWFFTFWISLFRPNGIFVNHFESSKENAQRFRGVIQRIIVVVVLLLNTSVFSNVTDAGLANDVLGQINTIAALIFCAAIIAPRFNRVLRSYEPETNKHHWLIRIVQIGFRLIPVGLIVLIVLGYYYTALNLIEHFIHSYIAWCVWWLVRNTIYRGITVSSRRLAHRRLAEKRRQKALENNYENISSDDVVAVGEPEESLALNDVRSQLLRFVDLFIWTALLGIFYYVWSDLVTVVSYLREITLWQQTTTTDAGTVMESITLFNLLVALVIVGITYVLVRNISGILEVLIFSRVNLSQGTPYTITTLLTYIFIAIGGAWAFATLGMSWSKLQWLFAALSVGLGFGMQEIFANFVSGIILLFERPIRVGDVVTINEVSGTVAKIRIRAITLIDFDRKEVIVPNKSFVTGQVTNWALSNTMTRLVISVGVAYGSDLTLVRQLLLQAADEQPTILRDPKPSAYFLTFGASTLDHELRVYVEQVGDRTSTTDALNRRINELFAEHNIDIAFNQLDVFIKNNDTGEEIPFVDVKK
What are the official names of this protein?
Uncharacterized MscS family protein HI_0195.1.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CD86_MOUSE
Sequence: MDPRCTMGLAILIFVTVLLISDAVSVETQAYFNGTAYLPCPFTKAQNISLSELVVFWQDQQKLVLYEHYLGTEKLDSVNAKYLGRTSFDRNNWTLRLHNVQIKDMGSYDCFIQKKPPTGSIILQQTLTELSVIANFSEPEIKLAQNVTGNSGINLTCTSKQGHPKPKKMYFLITNSTNEYGDNMQISQDNVTELFSISNSLSLSFPDGVWHMTVVCVLETESMKISSKPLNFTQEFPSPQTYWKEITASVTVALLLVMLLIIVCHKKPNQPSRPSNTASKLERDSNADRETINLKELEPQIASAKPNAE
What is the function of this protein?
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4.  May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation.  Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced.  Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation (PubMed:23241883).
What are the official names of this protein?
T-lymphocyte activation antigen CD86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RRP36_BLAGS
Sequence: MPISSKFNQRVRARLEEDEFEQFSGESTSDEGLEGGESVEDEEEEEENSAEDHSEEDDDEGEEDDDDDGDVEDSSSDINPSLNAISFGALAKAQASLGKRKRPTASTGGISPKRAKVPGRHSPTPSASSSGEKQEPEPELSEYQKHLAANAKKPPQKLTHRTSKHAPTIQSSRHAVSRKRTILEPPPVPKARDPRFDSVVLSHSTNGNSSTASNAAIHARKNYAFLDSYRKDEIAQLRKQVSTLQTKKHKTNYDERELARLKRQITSMSDRQRTFERKEMEREVLVQHRRKERELIREGKKSKPYFLKRGEVKKEAVAKRFTEMSGKEKQRALERRRKKVAGKERKEMPWGRRVVE
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ATPF_RHOJR
Sequence: MAANIAVLAQEESHNPLLPETYDIVWSIVCLVIVGFVFWKYVLPMFQKVLAERTEQIDGGIKRAEEAQAEAKAALEQYRAQLAEARTEAAQIREDARTQGQQIIAEMKAQAQEESDRIVAAGNNQLVAQRQQIVAELRADLGRTAVDLAEKVIGESLADDVKRAGTVDRFLNELDTIGANSAAGK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CH10_EXIS2
Sequence: MLKPLGDRIVIEVVKKEETTLGGIVLPGSAKEKPQEGKVVAVGTGRVTEQGVRVPLEVNVGDHVIYAQYAGSEVKVDGNEYLILRESDILAVAN
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK8_HUMAN
Sequence: MQCGLVGKIIKRFEQKGFRLVAMKFLPASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLRFKPEELVDYKSCAHDWVYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
What are the official names of this protein?
Putative nucleoside diphosphate kinase, NDK, NDP kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.