PharMolix/UniProtQA huggingface dataset:
Protein: HIS1_BLOPB
Sequence: MLDRSRLRIAIQKSGRLSKESQQLLEQCGIKINLQQQRLLAFAENMAIDIMRVRDDDIPGLVMDGIVDLGIIGENVLEEALLTRRSQGDNPCYIMLLRLDFGDCRLSMALPIDEPWNGPKSLQGKRIATSYPHLLKQYLDKLGIHFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLHEVEVIYRSKACLIQRSGELSNIKQSLINKLIIRIQGVIQARGSKYIMLHAPAEQLEEIINLLPGAESPTVLPLAGNQHRVAIYMVSNETLFWETMENLKNLGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_COLP3
Sequence: MAEENQVENSEAAQQSPEFAIQRIYTKDVSFETPNSPAVFQLDWKPEIQLDLDTRSTKLADNTYEVVLSVTVTATVEDKTAFLAEVQQAGIFTIGNLPEAQLAHTIGAFCPTTLFPYARETVASLVNRGSFPQFNLTPVNFEGLYASYVQQRATQENVAQSSETH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4920_ARATH
Sequence: MANLLETSIFFSSADKLLSFPPKNSQTHHLPFSAFINGGRKIRKSSTITFATDTVTYNGTTSAEVKSSVEDPMEVEVAEGYTMAQFCDKIIDLFLNEKPKVKQWKTYLVLRDEWNKYSVNFYKRCRIRADTETDPILKQKLVSLESKVKKIDKEMEKHNDLLKEIQENPTDINAIAAKRRRDFTGEFFRYVTLLSETLDGLEDRDAVARLATRCLSAVSAYDNTLESVETLDTAQAKFEDILNSPSVDSACEKIRSLAKAKELDSSLILLINSAYAAAKESQTVTNEAKDIMYHLYKATKSSLRSITPKEIKLLKYLLNITDPEERFSALATAFSPGDDHEAKDPKALYTTPKELHKWIKIMLDAYHLNKEETDIKEAKQMSQPIVIQRLFILKDTIEDEYLDKKTIVADETPKKEEEDTTIEDFLN
What are the official names of this protein?
Uncharacterized protein At4g37920.
Protein: END4_SULDN
Sequence: MSKFVGAHVSASGGVFNAVENAQKIGAKAFALFTKNQRQWSAKEFDSETIDKFKTALEKSGILPRHVLPHDSYLINLGHPELDAREKSLDAFLDEVQRCSLLGLDRLNFHPGSHLKKISEDECLANISESMNRVLDKTSGVSLVIENTAGQGSNLGWKFEHLAQIIDKVEDKSRVGVCIDTCHMFSAGYDIRTREAYDKSWGEFDKIVGFKYLMGMHINDSKAKFGSHVDRHNSLGVGEIGLDTFKFIMNDERMDDIPLILETIDDSIWAQEIRLLYSFVN
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: PYRE_SALTY
Sequence: MKPYQRQFIEFALNKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDKDLPYCFNRKEAKDHGEGGSLVGSALQGRVMLVDDVITAGTAIRESMEIIQAHGATLAGVLISLDRQERGRGEISAIQEVERDYGCKVISIITLKDLIAYLEEKPDMAEHLAAVRAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: PSA_FRAAA
Sequence: MTMPFGYASPEQQVRDKSEYARKGIARGRSVVVITYADGILFVAENPSATLHKISEIYDRIAFAAVGKYNEFENLRTAGIRLMDSRGYMYDRRDVTSRALANAYAQTLGAIFTESVKPYEVEIVVAEVGPTTDDDQIYKLTFDGSIADERGFVAIGGASDQVTTSLKEHHRDGQPLADALRVAVQALTVSVPPGLPQNGERVLTAANLEVGMLDRTRARRQFKRIAGPALAELLAQTATSS
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOTZ_DROSI
Sequence: MYFAIRLSFVLAVLFCLTGNGSARMLDADRNRLQQLQIRSQQSADANTQVDIAYEVIGIYDKYKGQGGSNVLREAQLNSQVNDFKRKTMVIDGVPAQGGVWGILGAIKKAADAVPDNVKKDAENLVKSSTKVLVRGIYDYLMGKMKQH
What is the function of this protein?
A humoral factor that may play a role in stress tolerance.
What are the official names of this protein?
Protein Turandot Z.
What is the protein family that this protein belongs to?
Belongs to the Turandot family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_PARPJ
Sequence: MPTINQLVRKGRQSETTKSKSPALQDCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHMVRGSLDTQGVKDRKQARSKYGAKRAKAGK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: Y1103_PSYA2
Sequence: MLDLANMTPKEVRALIGKNEINKPTSGMCKGHIQANLVIVPKNLAYDFLLFAQRNPKSCPILDVTDVGSSEPRLMAKGADLKSDVPMYRIYEFGELVAEVSDLTDYWREDLVCFLLGCSFSFESAMLNASIPVRHIEDNHNVPMYITNIETEPAGQFHGKMVVSMRPIPYPLITRAVQATSRFPQVHGAPIHIGDPSVIGITDIHSPDFGDASLIKEGEVPVFWACGVTPQSIAMTSKPELMITHSPGYMFICDPKDEDLAVL
What are the official names of this protein?
Putative hydro-lyase Psyc_1103.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: SECB2_FRATT
Sequence: MDQQAQPQFQIQKVYVKDLSFSIPNSDKIWTTNWKPELHTDLKVEATKLPEENTYETVLTLEVKVENDGMVAFEAEVKQAGIFTVANMQEAQIEHAKKAFCPNILYHYAREAISDLVISGGFPQLCLSAVNFDAMYQDSLKESADSKQH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB 2.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS3B_IBVM
Sequence: MLNLEAIIETGEQVIQKISFNLQHISSVLNTEVFDPFDYCYYRGGNFWEIESAEDCSGDDEFIE
What are the official names of this protein?
Non-structural protein 3b, ns3b, Accessory protein 3b.
Protein: RF1_NEIMB
Sequence: MKPSILEKLQQLSDRLEEVTHLLGQPEATSDMDNYRKLTREHAELTPVVEVFQNYRLAQSDLADAEEMLSDPEMKDFAAEEIEAAKAKIGELDTELQKLLLPKDADDDKNIFIEIRAGTGGDEAALFAGDLLRMYSRYAERNRWQVEIVSANESELGGYKEVIARIVGLGAYSRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPEADELEDIELNPADLRIDTFRASGAGGQHINKTDSAVRITHLPTGMVVECQDGRSQHANKAQAMKVLAARLNDAQKREAQAKEAAERKSLIGSGDRSERIRTYNYPQGRVTDHRINLTLHKLDFVMDGDLEEITNALIAEHQAELLAAMGD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_ANADF
Sequence: MSLLAAVFLGVLQAATEFLPVSSTAHLLVFGELLGHDLADPRFRAFATIIQTGTTLAVLVYFRTEILSLLAAGLRSLARRRPLETPQSRLAWFIVLGTVPAAVLGKLFEERIEALGNWVIAGSLVVLGLVLLAAERYARHLRTVEDVGARDAVLIGLGQALALVPGSSRSGTTITAGMLLGFTREAAARFSFLLSVPIILGAGGYKLWKTVPVLRGEPSWALATLVGTAVSAVAGYLVIDWLLGWLRTRTTHLFVVWRIAAGVALAILIWQGVLPAGHASVSAPAVEAARAADPDAPLGAALRR
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KGUA_PORGI
Sequence: MTKLIIISAPSGTGKSTVIERLLTDRELNLHFSISATSRAPRGEEQNGREYYFLSPEEFRRRIEANEFVEYEEVYRDKYYGTLKSEVERILKEEKNVIFDVDVVGAQSIKKYYGDRALAIFILPPSIEELRSRLQKRGTDSMETIKQRVDKAEKEIGYAHLFDLRFVNDDLVTCVEQIRKAIAQFIAK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRP90_SOYBN
Sequence: MSEHSFAFAYTVFFMVSVATMSELSSRRYELTQSEKRVIPTRHSTMKSCPWVVFHTRATLTRSFPCLCSNLNPSTTSCLAIFSEHSYVVVF
What is the function of this protein?
Possible role in gene regulation during soybean nodule differentiation.
What are the official names of this protein?
DNA-binding protein DRP90.
Protein: RL14_CAMJE
Sequence: MIQSFTRLAVADNSGAKELMCIKVLGGSKRRYATVGDVIVASVKKALPNGKVKKGQVVKAVIVRTKKEIHRDNGSLIRFDENAAVILDNKREPIGTRIFGPVGREVRYGGFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: DEOC_ECOLC
Sequence: MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFH52_TRYCR
Sequence: MQARGTVKVQGDANVDGKMSTGQHPHHQHLNSTQANATTTALEYRAMNRPLYRGPISHNIISEMAEGFYVLSGGYKKLFIPSKDVYALMQNVGMHLTEEEFHDALRVIGQSEPQNADELSFSDFLLLMTREVDDTMADELRSAFFHYDKHKTGYVTRKQFTELFATLAERSTPEELEELLAVAEVDETDDKIDYNRFVNELTSRVNCM
What are the official names of this protein?
EF-hand protein 5 variant 2, EFH5, Calmodulin-ubiquitin-associated protein CUB2.8.
Protein: MLTC_ECO57
Sequence: MKKYLALALIAPLLISCSTTKKGGTYNEAWVKDTNGFDILMGQFAHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRAIIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLKNRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: FPG_BRUA1
Sequence: MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGLGNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SYM_SHISS
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRSDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVH_MYCAV
Sequence: MSPQTHTLSVLVEAKPGVLARVAALFSRRGFNIESLAVGATEQKDMSRMTIVVSAEETPLEQITKQLNKLINVIKIVELEDGNSVSRELALIKVRADAGTRSQVIEAVNLFRAKVIDVSPEALTIEATGDRGKIEALLRVLEPSVSVRSSNREWCRCPGPRGIGTAK
What are the official names of this protein?
Acetolactate synthase small subunit, Acetohydroxy-acid synthase small subunit, AHAS, ALS.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
Protein: CHCH7_MOUSE
Sequence: MPMVTRRLRDPDINPCLSESDASTRCMDENNYDRERCSSYFLKYKNCRRFWNSVMIQRRQNGVQPSMPTAAERDEILGAMQKMPY
What are the official names of this protein?
Coiled-coil-helix-coiled-coil-helix domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the CHCHD7 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: Y509_MYCBO
Sequence: MRPAIKVGLSTASVYPLRAEAAFEYADRLGYDGVELMVWGESVSQDIDAVRKLSRRYRVPVLSVHAPCLLISQRVWGANPILKLDRSVRAAEQLGAQTVVVHPPFRWQRRYAEGFSDQVAALEAASTVMVAVENMFPFRADRFFGAGQSRERMRKRGGGPGPAISAFAPSYDPLDGNHAHYTLDLSHTATAGTDSLDMARRMGPGLVHLHLCDGSGLPADEHLVPGRGTQPTAEVCQMLAGSGFVGHVVLEVSTSSARSANERESMLAESLQFARTHLLR
What are the official names of this protein?
Uncharacterized protein Mb0509.
What is the protein family that this protein belongs to?
To M.leprae ML2432 and S.coelicolor SCO3347.
Protein: DCUP_SALEP
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTIPDAMGLGLYFEAGEGPRFTAPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHLLLDKLAKSVTLYLNAQIKAGAQSVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGHKVALQGNMDPSMLYAPPARIEDEVATILAGFGQGEGHVFNLGHGIHQDVPPEHAGAFVEAVHRLSAQYHN
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_MYCCT
Sequence: MSKEQILLRINQLKEQLNLWSKQYYVDDNPSVDDTEYDLALKELISLENLYPEFITSDSPSQKVGGTVSEKFLKITHKTPMLSLGNVFNFDEFLEFNTQVSKVSNNLNNEYVAELKIDGLSISLVYENGVLVSAATRGNGVIGEDVTTNVRTIKSIPLKISKKERVEVRGEIYLSKAEFEKINQKRLLNNEDLFINPRNAAAGTLRQLDSKIVASRNLDAFLYYYISDDSPNLNQYESILKLNQLGFKTNKETMLCKNLDQIKAYIDKYTNLKNDLDYQIDGIVFKINDKNLQNSLGFTSKIPKWAIAYKFPAEIKQTKLLDIFATVGRTGKITYNAKLEPVFLMGATISAATLNNAEYIKSKDLRINSIVKIKKAGDVIPEVIEAIKDETFYNLEVFQPILYCPNCHSLLEKNENEVDQFCINSSCSMKILRSLQHFSSREAMNIVSLGDRSLEILFNLEIIQNISDIYKLEEYKDQILAIENFGLKSYLNLIDSINMSKNNSLEKVLFGLGIRHIGSKTAKILARKYQNIDNLMKASYDELIQINSIGESLALSIIDWFKIEDNLKLINELKSFNINFNYLGAKINSDSIIANKTFVITGTLTRPREEFKTLIENNAGKISGSISKQTDYLLAGNNVGSKLEKAKKLGVIIIDEQQFFDLLKSEKG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: COX6C_MACSL
Sequence: MAPEVLPKPQMRGLLARRLRFHMVTGFVLSLGVAALYKVGVADKRKKAYADFYRNYDAMKDFEEMRKAGIFQSVK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6C, Cytochrome c oxidase polypeptide VIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6c family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ASSY_XANAC
Sequence: MMSAASTNPEFPIATSGTKDIVLAFSGGLDTSFCIPYLQERGYAVHTVFADTGGVDAEEREFIEKRAAELGAASHVTVDGGPAIWEGFVKPFVWAGEGYQGQYPLLVSDRYLIVDAALKRAEELGTRIIAHGCTGMGNDQVRFDLAVKALGDYQIVAPIREIQKEHTQTRAYEQKYLEARGFGVRAKQQAYTINENLLGLTMSGGEIDRWEAPGEGARGWCAPRSAWPSEALTVTLKFVEGEAVELDGKPLPGAKILAKLNTLFAQYGVGRGVYTGDTVIGLKGRIVFEAPGLISLLTAHRALEDAVLTKQQNRFKPDVARKWVELVYEGFYHDPLKSDIEAFLKSSQAKVNGEVTLETRGGRVDAVAVRSPHLLNTKGATYAQSADWGVEEAEGFIKLFGMSSTLYAQVNR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_DINSH
Sequence: MAKKAMIEREKKRQKLVAKYAAKRAALKEIANDDSKPMEERFKARLKLAELPRNSSATRLHNRCQLTGRPHAYYRKLKISRIALRDLGSAGQIPGLVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RSMG_CLOBK
Sequence: MEFFNILQSACNDVNLDFNDKKYNQLISYKNLIQEWNKKINLTAIVEDDEIIKKHFIDCIKIFKSSPIGEAKSLIDIGTGAGFPGIPIKILKEDIEITLLDSLQKRINFLNIVIGELQLKNIQCLHGRAEDYAQEIQHRQKYDIAVSRAVANLAVLSEFCIPFVEKGGYFIAMKGPSVEEEITAATKSIEILGGKIEDIIKIDIEDTDLKHNLVIIKKVKETGKRYPRKPGIIKKNPLK
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBT_SHESH
Sequence: MFNISPANHEFDDEIQSKIDNKTKPLGALGELENLAKQLALVLGKDKPEIINPKLLVFAADHGIASSGVSIAPSEVTTQMVMNFVAGGAAINVFCRQVGLDMEVIDCGILQPLEGVEGVIDQRLGAGTGAIHKQAAMTLGAVKQGLEMARTRIELHHQQGCNLIALGEMGIGNTSSAAAIMATVMGMKGVDCVGRGTGIDAATLKRKQMLVEQALHIHEAELTDPYNILACLGGFEIVQMTGAMLAAAERNMLVIVDGFIATAAAMVAVQINANVRDYMIFGHQSDERGHCLMMEHLQARPLLRLGMRLGEGSGAVLALPLIRAAAGFYNEMASFSDAGIEI
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: SGF29_RAT
Sequence: MALVSADSRIAELLTELHQLIKQTQEERSRSEHNLVNIQKTHERMQTENKISPYYRTKLRGLYTTAKADAEAECNILRKALDKIAEIKSLLEERRIAAKIAGLYNDSEPPRKTMRRGVLMTLLQQSAMTLPLWIGKPGDKPPPLCGAIPASGDYVAKPGDKVAARVKAVEGDEQWILAEVVSYSHATNKYEVDDIDEEGKERHTLSRRRIIPLPQWKANPETDPEALFQKEQLVLALYPQTTCFYRALIHTPPQRPQDDYSVLFEDTSYADGYSPPLNVAQRYVVACKEPKKK
What is the function of this protein?
Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes (By similarity).  SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3) (By similarity).  In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me (By similarity).  Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival (By similarity).  Also binds non-histone proteins that are methylated on Lys residues: specifically recognizes and binds CGAS monomethylated on 'Lys-491' (By similarity).  May be involved in MYC-mediated oncogenic transformation (PubMed:17334388).
What are the official names of this protein?
SAGA-associated factor 29, rSGF29, Coiled-coil domain-containing protein 101, SAGA complex-associated factor 29.
What is the protein family that this protein belongs to?
Belongs to the SGF29 family.
Protein: MURD_SHIFL
Sequence: MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELSSFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALTMPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALVALALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLVRYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETMEQAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.