PharMolix/UniProtQA huggingface dataset:
Protein: RABEK_BOVIN
Sequence: MKQLPVLEPGDKPRKETWYTLTLVGDSPCARVGHSCSYLPPVGDAERGKVFIVGGADPNRSFSDVHTIDLGTHQWDLATSEGLLPRYEHTSFIPSCTPHSIWVFGGADQSGNRNCLQVLNPDTRTWTTPEVTGPPPSPRTFHTSSAAIGDQLYVFGGGERGAQPVQDVQLHVFDANTLTWSQPETHGKPPSPRHGHVMVAAGTKLFIHGGLAGDNFYDDLHCIDISDMKWQKLRPTGAAPTGCAAHSAVAVGKHLYVFGGMTPTGALNTMYQYHIEKQHWTLLKFENSPPTGRLDHSMCIIPWPGTCTSEKEDSNSATVNRDAEKGDSTEKGVTQGGDSQEESQADTLLCFVFGGMNTEGEIYDDCIVTAVD
What is the function of this protein?
Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
What are the official names of this protein?
Rab9 effector protein with kelch motifs.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane. Note=Interaction with PIKFYVE and subsequent phosphorylation recruits it to the endosomal membrane.
Protein: ARI1_YEAST
Sequence: MTTDTTVFVSGATGFIALHIMNDLLKAGYTVIGSGRSQEKNDGLLKKFNNNPKLSMEIVEDIAAPNAFDEVFKKHGKEIKIVLHTASPFHFETTNFEKDLLTPAVNGTKSILEAIKKYAADTVEKVIVTSSTAALVTPTDMNKGDLVITEESWNKDTWDSCQANAVAAYCGSKKFAEKTAWEFLKENKSSVKFTLSTINPGFVFGPQMFADSLKHGINTSSGIVSELIHSKVGGEFYNYCGPFIDVRDVSKAHLVAIEKPECTGQRLVLSEGLFCCQEIVDILNEEFPQLKGKIATGEPATGPSFLEKNSCKFDNSKTKKLLGFQFYNLKDCIVDTAAQMLEVQNEA
What is the function of this protein?
NADPH-dependent aldehyde reductase involved in the detoxification of aldehyde inhibitors derived from lignocellulosic biomass conversion.  Reduces commonly detected inhibitors in biomass conversion hydrolysates such as furfural, 5-hydroxymethylfurfural (HMF), cinnamic aldehyde, benzaldehyde, phenylacetaldehyde, and anisaldehyde.
What are the official names of this protein?
NADPH-dependent aldehyde reductase ARI1.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NKG2A_MACMU
Sequence: MDNQGVIYSDLNLPPNPKRQQQKPKGNTSSILVTEQEITYAELNLQKTSQDFQGNDKTNHCKDLLSAPEKLIAGILGIICLVLMASVVTIVVIPSTLTQKHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKEKRTWAESLLACTSKNSSLLSIDNEEEMKFLTAILTSSWIDVFRDSSHHPWVTINGLTFKHEIKESDHAEHNCAMLHVRGLFSDECGSSKIYHCKHKL
What is the function of this protein?
Immune inhibitory receptor involved in self-nonself discrimination.  In complex with KLRD1 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule MHC-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia molecules.  Enables cytotoxic cells to monitor the expression of MHC class I molecules in healthy cells and to tolerate self.  Upon MHC-E-peptide binding, transmits intracellular signals through two immunoreceptor tyrosine-based inhibition motifs (ITIMs) by recruiting INPP5D/SHP-1 and INPPL1/SHP-2 tyrosine phosphatases to ITIMs, and ultimately opposing signals transmitted by activating receptors through dephosphorylation of proximal signaling molecules.  Key inhibitory receptor on natural killer (NK) cells that regulates their activation and effector functions.  Dominantly counteracts T cell receptor signaling on a subset of memory/effector CD8-positive T cells as part of an antigen-driven response to avoid autoimmunity.  On intraepithelial CD8-positive gamma-delta regulatory T cells triggers TGFB1 secretion, which in turn limits the cytotoxic programming of intraepithelial CD8-positive alpha-beta T cells, distinguishing harmless from pathogenic antigens.  In MHC-E-rich tumor microenvironment, acts as an immune inhibitory checkpoint and may contribute to progressive loss of effector functions of NK cells and tumor-specific T cells, a state known as cell exhaustion.
What are the official names of this protein?
NKG2-A/NKG2-B type II integral membrane protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-A/B-activating NK receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: RL27_HUMAN
Sequence: MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSVDIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25957688, PubMed:25901680, PubMed:32669547).  Required for proper rRNA processing and maturation of 28S and 5. 8S rRNAs (PubMed:25424902).
What are the official names of this protein?
60S ribosomal protein L27, Large ribosomal subunit protein eL27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL27 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: MIAB_TREDE
Sequence: MTYFFETYGCQMNQAESSSMEQILLEKGWTNSSDAEHCDLLIINTCSVRITAENRVLGRLGHFSGLKKKRKFFVLLIGCMAERLYTEIQKEFPLIDYVVGMFERNLLPQIFDEIKARLKNDNYMAEFTHDNIEEKPVSGYYFAPLSHSPKSFQSYVPIMNGCNNFCTYCIVPYVRGREVSRPVNEILQEITELSSRGVREITLLGQNVNSYKGEDGEGRLIDFPKLLTLIAREADKTDMIRWIRFMSSHPKDMSDALIDTIAAEKRLCKLVHLPVQHGSDTILKRMNRVYTIEHYKNRIKRLKETIPDIALSTDILMGFPGETEDDVKATLDLMQEIEFDSAFMYHYNPREGTKAFNYPDRIPEEVKIERLGRVIDLQLKITAKKMKAKLGKKVDILVESHSRNERSELFGHTEQGEMTVIQGNPPESLIGNFAHAELKELKGKTFRANLN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_ECOLU
Sequence: MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVGNGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: DXS_CLOB8
Sequence: MNLLDKLNFPEDLKKLNEEDYKVLSSEIRKFLIDSVSKTGGHLASNLGVVELTLSLFKAFSFDKDKIVWDVGHQSYIYKILTGRKEGFKKLRKYDGISGFPKRNESKYDYFDTGHSSTSISAALGIARARDLKKEKYNVISVIGDGALTGGMAIEALNDVGFRKTKLIIILNDNQMSISTNVGGLSRYLNKLRIAPVYNKLKTDIHASLDNSNLGKNIAGKISKVKDSIKQLIVPSMFFENMGVKYIGPIDGHDIDAMTEVFIKAKEINEPVIIHILTQKGKGYALAEESPSKYHAVGAFNLESGESNASPKNSYSKAFGKALVNLGAQDEKIVAITAAMPEGTGLKCFSQKFRDRFFDVGIAEEHAVTLAAGMASNGLKPVFAVYSTFLQRAFDQVLHDVCIQNLPVVFAIDRAGIVGEDGETHQGINDLSYLSMIPNIHIVVPKCLEEVDVLLKWAINKNAPVAIRYPKGGNIIDTLSPIKEVVEGQWEIVNRGSKVCIIATGRMVQHAMIAKEFLYEKGLNPTVINATFVKPIDKKLLENIKKEGYNILTIEDNIIKGGLGSAVKDYLSEIDYKGTIRSLGYDDEFIPQGNVEILYKTYKLDYENISKIVMKLYD
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: METK_SYNSC
Sequence: MSRYVFTSESVTEGHPDKICDQVSDAVLDALLAQDPSSRVACETVVNTGLCMITGEVTSKAQVDFIHLVRNVIKEIGYSGARAGGFDANSCAVLVALDQQSPDIAQGVNEADDHAGDPLDLVGAGDQGIMFGYACNETPELMPLPISLAHRLSRRLAEVRHNGTLGYLLPDGKTQVSVVYENDKPVSIDTILISTQHTAEVDGISDEQGIRERITEDLWTHVVEPATADLALKPSREATKYLVNPTGKFVVGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYVAKCLVAAGLAERAEVQLSYAIGVAKPVSILVESFGTSALANDALTALVQEHFDLRPGAIIETFGLRNLPQQRGGCFYQDTAAYGHFGRNDLNAPWEDVTAKSQELKQVAAA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1763_STAES
Sequence: MAMTVKKNDNEVRIQWRVADIKIPNNEIKNVTQDQDIHAVPEENGKEISRIGSTFGKTNRVLIDTDQHLYIIYTQNDQKVYNELTK
What are the official names of this protein?
UPF0457 protein SE_1763.
What is the protein family that this protein belongs to?
Belongs to the UPF0457 family.
Protein: PYRE_STRPC
Sequence: MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSYPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFVYIRSKPKDHGAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RL2_ROSS1
Sequence: MPVKKYKPTSPGRRNMSVSTFEEITKKEPERSLLEPLRKKAGRNNYGRITVRHRGGGHKRHYRRIDFKRDKIGVPAKVAAIEYDPNRSARIALLHYVDGEKRYILAPLGLNVGDTVMSGPDADIRVGNALPLRQIPLGTQVHNVELEKGRGGVMVRSAGAAAQLMAKEGNYATLRMPSGEVRRVFIECMATIGQVGNLDHQNIRLGKAGRKRWLGRRPEVRGAAMNPRDHPHGGGEGRAPRGMPTPKTKWGKPARGVKTRHNPRTDPFIIRRRTR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RNPH_CARHZ
Sequence: MRIDGREKDQLRTVKITTNYIKHAEGSVLIEMGDTRVVCTATVEDKVPPFAKGEGKGWITAEYGMLPRSTETRNVREATKGRQSGRTLEIQRLIGRALRGVVDLKALGERTLWIDCDVIQADGGTRTAAITGSFVALALALNKLVEEGILPVIPLKDFVAAVSVGIVDGEEILDLNFEEDSKALVDMNVVMTGSNRFVEVQGTGEEATFSMEELQRLLTLAQKGIRELIELQKQALGDIARRIGMENAADSNSQ
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RL10_AERS4
Sequence: MALGLEDKKAIVAEVNEAAKGALSAVVADSRGVTVDKMTVLRKTAREAGVYMRVVRNTLLRRAVEGTEFACLNDVLTGPTLIAFSNEHPGAAARLFKEFAKANQKFEIKAGAFNGEFIAAAQIDRLATLPTYDEAIAKLMATMKEASAGKLVRTIAAVRDQKQAAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: NADK_ECO81
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIAHELQLKNVKTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFCS_SACS2
Sequence: MSTKVEEILWAEKYRPKTLDDIVNQREIIDRLKKFVKEKNMPHLLFAGPPGTGKTTAALALVHDLYGDNYTEYFLELNASDERGIDVIRNKVKEFARTVIPGDIPFKVVLLDEADNMTADAQQALRRTMELYTENTRFILACNYLSKIIEPIQSRTALFRFYPLKKEDVVNRLIYIAKNEKAEYDQKALETIYDITMGDMRKSINILQAASAYGKISVEAVFKVLGLAQPKEVREMINLALQGKFTQARDKLRTLLITYGLSGEDIVKQIHREITSSEIQISEELRVLLLDYIGETEFRIIEGADDEIQLSALLAKMAIYGNKYIGSENR
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.  The complex possesses DNA-dependent ATPase activity.
What are the official names of this protein?
Replication factor C small subunit, RFC small subunit, Clamp loader small subunit, SsoRFC small subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcS subfamily.
Protein: PTHB_ERWAM
Sequence: MANTIEIRKGESGWGGPLSINVTAGKKIVYITAGTKPAIVDHLVALTGWEAVDGFKQGEPPAEEIGVAVIDCGGTLRCGLYPKRRIPTINIHATGKSGPLAQFITEDIYVSGVRVADIRVANDAEAAPPEVAVADVAVNAGKGTGRDYDTSKKITEQSDGLLAKVGMGMGSAVAILFQSGRETIDTVLKTILPFMAFVSALIGIIMASGLGDFIAHGLTPLANSPVGLVTLALICSFPLLSPFLGPGAVIAQVIGVLVGVQIGQGTIPPHLALPALFAINAQAACDFIPVGLSLANARQETVRVGVPAVLVGRFITGAPTVLLAWAASSFIYH
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II complex composed of SrlA, SrlB and SrlE is involved in glucitol/sorbitol transport.
What are the official names of this protein?
PTS system glucitol/sorbitol-specific EIIB component, EII-Gut, Enzyme II-Gut, Glucitol/sorbitol-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL5_RHIL3
Sequence: MAEAKYEPRLKKEYVERIRKALQEQFSYANEMMIPKLDKIVINMGVGEATADSKKPTVAAADLAAIAGQKPVITRARNSIAGFKVREQMPIGAKVTLRGARMYEFMDRLVNIALPRVRDFRGLNPKSFDGRGNFAMGIKEHIVFPEINYDKVDQMWGMDIIVCTTATTDDEARALLKEFSFPFRQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: CLSPN_XENLA
Sequence: MAALCEEEQVFLEPEDISLKIVETDSDSGQGSCEMADQNKLLGCVEDKDTDDEILVRKKSKKKEVLVDSDSDEELEMRNFADNVKGHSDNEENEETMSAYREKPRKIRSAVLDSDNSDHELDVQISTSQNAAEIPESEHDSLEKETHTVKPKTSKSLKKQTDTNKEEIVKNKSKRKIPKEKIKRRTKQKSKAVAEARPNLNDSGCLLTDGDLFDNGVENEMDSNEEEDSLEAIRAKMKSKLNSHSAENFEDFELDTEGNQESPEKRKERKAARLGKEAMKQMHSETQRLIRESSVSLPYHLPEPKTIHDFFKRRPRPLCQGNAMQLIKSTKYQPCTEEKKKPNEEICAEVPEFDYVSKEDLEISPEQPLLNTQCSHAAVLCVVQNDARTEGLSKSTEAVVTGQMNDHEDAFSDSNIVHEQETVGLITVTETFQTPFIPQPESVVCEQIQNDVVEMQRMPEQPTHKPKLSKLEKLKALGVDLSIKPRLCPDDGSFVNLDEPKPNKEFEALKERFLKHTLQKSKPRTERKVNLNIIRKETTADGKEELKADVVPIVMATEKPDKSIYQKPGEKLQVLKVKLQEAMKIRRSEERLKRQALYKLDNEDGFEDDEEEEEMTEESEDDGDGNAETADYPGGEDEEEVGDAEDDNDEDDTVNDRLLGNVPEIVIPLPRPVTTDSSLMLFKDNSSKLGDSLPDESGCKRSSRLEYEEDSLLPQLKENSHNSSFELISSMIPSYQPCNKTTRVVINSNNLGFRSPSPVHFKTSFLSSASKSSGKMSEPSLPVEDSQDLYNASPEPKASYLCAGRNSQFQFSLEDDTQSQLLDADGFLNVGRHKSSSAKHRLALDTMDENAMDANMDELLDLCSGQFKESLSGTSQAAESDAKKQPMDELLELCSGKFVSQADCSTQDSSASAKDRSTAVKKDISDEVATVSSSFLTEREQEEDEEEEFGEFKLLPCDDSESENEEQNEEEEEEEDAKDDEDEEEILQKQQKRKLRLNDFMEDEAELSGSDVGSGDEYEGDDDEYEEEAIDEDLPSDEELQDQVNKIHMKVTMDEDQRQLRFYQERYLADGDLHSDGPGRTRKFRWKHLDDASQVDMFRRDSELEEVDGENEETEETELKWRKERFEREQWLREQPQGSRDNNEEEEEDIGEDSQFMKLAKKVTAKALQRKVSTETNEPKKPGPRNPYEVIRPFSLPKLRTGSLLSKPKEVLQKLAAVSDLNPNAPRNSRNFVFQTVSPGKKEETTDKPRSKVRKNIAVAMPSPKRFKRDSTPTVKSRSIFQLLE
What is the function of this protein?
Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by UV irradiation.  Adapter protein which binds to the checkpoint kinase chek1 and facilitates the phosphorylation and activation of this kinase by the ATR-TREX1/ATRIP kinase complex.  Also associates with chromatin during S-phase, and this requires the pre-replication complex (pre-RC), cdc45 and cdk2.  This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks.
What are the official names of this protein?
Claspin, xClaspin.
What is the protein family that this protein belongs to?
Belongs to the claspin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDH_ECOSM
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEKNALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: LIPA_NEUCR
Sequence: MASPVPIQRLQAPLRRSLARAAALSTRSYATIPSGPSSQPTSQESSSAASASAPATKPRPTYFKDTTLASLDDFIANQSSAAPLAPSEAYTLRTAEVGPAGKKRTITRLPEWLKTPIPSAGANPEFAKIKADLRGLNLHTVCEEARCPNIGECWGGSNKAAATATIMLMGDTCTRGCRFCSVKTSRKPPPLDPHEPENTAEALARWGLGYVVLTSVDRDDLADGGARHFAETIRRIKQKKPTLLVEALTGDFAGDLDMVKIVAESGLDVYAHNVETVENLTPYVRDRRATFRQSLKVLEHVKKVRGKEGIITKTSIMLGLGETEEELWEALRELRKVDVDVVTFGQYMRPTKRHLAVEKYITPDEFELWRQRALDMGFLYCASGPLVRSSYKAGEAFIENVLRKRSGEKVVSEALGQAVAAEEATSVQSS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PRIA_THEMA
Sequence: MYYKVAVSGSGKVLNVFSSEELLIGERVWLNWRNGKVKGYVLERSLSHENEATPSERDGKSFLSEGHVEIAKWVSERFFSPLGMVFDLFFPQGIDDYKEEVVVSESPFLDFDRMTLRDFLENFGEKALKEMVKKGLVRVEKNFYVKEPRPRVKKRLFLKKRISEIIREHLTVKQRMVVEYLQFNDGVPLEELLEDLEVSKSVIETLQRKNIVEIVSGDVFPKKRRILRGDFKGNISKENLFFGPTGSGKTEALFELIDVYSRKGTVLFLVPEVSVLTHTLSRLKGAFPDLKIGIYHSYLSRARKNLEWYKAASGKIDVLLGTRSAVFVPVKNLSLLIVDEEHDESFYQHTRPSYDAIVVARKISEVFDVPIILSSATPDLWTYREAKEGRIRTFNFTRRFGSLSVEVVDMRNEEKIGSFAKKTLDRIEETLEEGKRVLIYVRRKGFWGRVQCEVCGYVLKCENCDVSLVYHSDTHSLKCHQCGREYGLVESCPRCGGRLVGRTAGTERVERELKRYFPTRRIARVDREVVDNIMELESYIDKLIRGEIDILVGTRLITKSLSVPEIGLVCIMDVDSLIFNPDYSSSLRTFQLVVQALGRASRGDQGKAIIQTYNPEDTIIRKALEEDVNGFYAEELERRKALGYPPYRHLIQVAVKSKNPEVGKNSLTSLKEFLKGEEVLGPVEHWVFKLRGFYRHHLIVKTEDLERVLPKLEKALRILGIDAIVRVDPPTLEVSD
What is the function of this protein?
Involved in the restart of stalled replication forks.  Recognizes and binds the arrested nascent DNA chain at stalled replication forks.  It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
What are the official names of this protein?
Primosomal protein N', ATP-dependent helicase PriA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PriA subfamily.
Protein: PYRB_XANC8
Sequence: MTTMQLDSDGRLRHLLTLEGLPRATLLQLLDRAGQIRDAAVGRVGKRSVLAGTAVCTLFFEPSTRTRSSFHLAAQRLGADVLNFDASTSSTRKGETARDTLKNLEAMGVRGFVVRHPEDGAVERLAEAAGEGTALINAGDGRSAHPTQGLLDMLTLRQAKGTDFSKLKVVIVGDVKHSRVARSDLHALRTLGAGEIRVCGPASLLPDDDMLDGCVVGEDFDAMLEGADALMMLRLQRERMEEGLVPSLEQYHADYGLTRERLARAGRDAAVLHPGPINRGVEITDEVADGAQSCVLRQVANGVAVRMAVLETLLG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: UREA_ARATH
Sequence: MKLLPREIEKLELHQAGFLAQKRLARGIRLNYTEAVALIATQILEFIRDGDKSVAELMDIGRQLLGRRQVLPAVLHLLYTVQVEGTFRDGTKLVTVHEPISLENGNLELALHGSFLPVPSLDKFPEVHEGVIIPGDMKYGDGSIIINHGRKAVVLKVVNTGDRPVQVGSHYHFIEVNPLLVFDRRKALGMRLNIPAGTAVRFEPGERKSVVLVNIGGNKVIRGGNGIVDGLVDDVNWTVLMETMERRGFKHLEDIDASEGIAGEDPRFTTMISREKYANMYGPTTGDKLRLGDTNLYARIEKDYTVYGDECVFGGGKVLREGMGQGIEQAEALSLDTVITNSVIIDYSGIYKADIGIKNGHIVGIGKAGNPDTMHGVQNNMLIGNKTEVIAGEGMIVTAGAIDCHVHFICPQLVYEAVSSGITTMVGGGTGPAYGTRATTCTPSPFDMKLMLQSTDSLPLNFGFTGKGNTAKPLELRHIVEAGAMGLKLHEDWGTTPAAIDNCLAVAEEYDIQVNIHTDTLNESGFVEHTINAFRGRTIHTYHSEGAGGGHAPDIIRVCGVKNVLPSSTNPTRPYTKNTVDEHLDMLMVCHHLDKNIPEDVAFAESRIRAETIAAEDILHDMGAISIISSDSQAMGRIGEVISRTWQTADKMKAQRGAIDPNMADDDNSRIKRYIAKYTINPAIANGFADLIGSVEVKKLADLVIWQPAFFGAKPEMIIKGGNIAWANMGDANASIPTPEPVISRPMFGAFGKAGSENSVAFVSKAALRKGVKELYGLKKRVVAVSNVRQLTKLDMKLNDALPEITVDPETYVVTANGEVLTCAPADSVPLSRNYFLF
What is the function of this protein?
Urea hydrolase involved in nitrogen recycling from ureide, purine, and arginine catabolism.
What are the official names of this protein?
Urease, Urea amidohydrolase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
Protein: PSBL_AGARO
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: IF3_PSEPH
Sequence: MIIKRDMRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVPPVCRVMDYGKSIFEKKKQIAAAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGDRAKVSLRFRGREMAHQELGMELLKRVEADLQEYGSVEQHPKMEGRQLIMVIAPKKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.