PharMolix/UniProtQA huggingface dataset:
Protein: RL9_VESOH
Sequence: MQVILLENIQKLGNLGDIINVKAGYTRNFLIPKGKAKLATKTNLVEFELIRAKLQIAEAKTLKNAKAIETKMTNTICIIQANASEEGKLFGSINTTDIQTSLIKSGFKIEKRNIDIPETIRHTGEYKININLHTNITVSVKIVIEALQKV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: AROB_LISMH
Sequence: MPEITVRAKSKTYPVYINEFALEDVREKWTESLAKFSHVFVLTDEHVAELHKAKLDAVLADLPVVTYYVAPNGEEAKTFRVYEDVMTKLIETGLDRKAVLIAFGGGVIGDLGGFVAATYMRGIPFYQVPTTVLAHDSAVGGKVAINHPLGKNMIGNFYQPEAVIYDTQFFATLPEREMRSGFAEMIKHALISDQTLLRALMDTFTEPKDFYTKDLTPFLQRGIEIKANIVAQDETEQGVRAYLNFGHTFGHALEAYGNFGKWLHGEAITYGMIYALTMSEAIYGLDFDLAEFKTWLKQLGYDTTFDATVPFSKILENMRHDKKTTFNEISMVLLEEIGKPVIFKAEDDLIFETYKRVMRNGGNGI
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_CHLCH
Sequence: MIVIDGKKVSLELKNELRERVEALNAKCGKVPGLTVIIVGEDPASQVYVRNKAKSCKEIGMNSTVIELPADTTQEHLLKIINDLNNDDTVHGILVQQPMPKQIDEFTITLAIDPAKDVDGFHPENLGRLVMGHLDKCFVSCTPYGILELLGRYNIETKGKHCVVVGRSNIVGKPMANLMLQKLKESNCTVTICHSATPNITEFTKQADILIAAIGKANFITADMVKAGAVVIDVGINRVDDASAKNGYRLVGDVEYAGVSALASAITPVPGGVGPMTIAMLLKNTVQSFQRVNGL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MS4A3_MOUSE
Sequence: MKPEETGGSVYQPLDESRHVQRGVLQALGAIQILNGILILALGIFLVCLQHVSHHFRHFFFFTFYTGYPLWGAVFFISSGSLTVAAGRNPTRMLMQNSFGINIASTTIAFVGTVFLSVHLAFNTQAFKGCQSSPSPDVCISLGSSSDGLVSLMLILTLLELSVTISISAMWCLGNVCGLREAITSPPNSVESGILPEGSDSENLNTQPQASEE
What is the function of this protein?
Hematopoietic modulator for the G1-S cell cycle transition.  Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP) (By similarity).
What are the official names of this protein?
Membrane-spanning 4-domains subfamily A member 3, Hematopoietic-specific transmembrane protein 4, HTm4.
What is the protein family that this protein belongs to?
Belongs to the MS4A family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RRF_SALCH
Sequence: MISDIRKDAEVRMEKCVEAFKTQISKVRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMGPAVEKAIMASDLGLNPSSAGTDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKAISEDDDRRSQEEVQKMTDAAIKKVDAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK1_STRAW
Sequence: MTVTRVGLVMHGGRAQAGDAARIVRGWCAERGVHCADIDVWRDDTRHSAREEVAAAGNPDLIVTLGGDGTFLRGARLAAENDALVLGVDLGRVGFLTEVPAAAVCEALEAVQEDRITVESRMLLTLRASRRLQVPTGMEALLRYGRGPLLPPPRVRTDCAEGDDWGIALHVTALNDIVLEKLARDRQVSVGVYLAGRLLASYSADALLVATPTGSTAYSFAAGGPVVSPRAEALIFTPVAPHMAFNRSVVAAPDEPIALRVLDRSGPAAVSVDGQLRGVLDPGDWIGVYAAPRRLKAVRLGPMDFYGRLRERMNLTDAPAAVADGQAAPLWPVTSAPPADLAHLTLPPGPGDTPSAS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 1, ATP-dependent NAD kinase 1.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDA7L_RAT
Sequence: MELATRSQIPKEVADIFNAPSDDEEFVGFQDDVPMENLSESCGSLDSLELEKQNACLHSKYFTEELRRIFKEDTDSDNEDFEGFTESELNIGSNPELIESELSDGDKTHPMMSDEEDDDDEEEAAPRRGRQSTRSSFGLRVAFQFPTKKTAKTPDKNSPHLLGGKTDLRREKSCRQPKEKEDSASDAEDESRAESQETSDALLKRAMNIKENKAMLAQLLAELNSVPDFFPVRTPPSASRRRTPRRAFSEGQITRRVNPTRSARPPEKFALENFTFSATKLTEELYSFRRRKTISGGKCQKYRRHRISSFRSVKDITEEELENIAITVRDKVYDKVLGNTCHQCRQKTIDTKTVCRNQGCGGVRGQFCGPCLRNRYGEDVRTALLDPKWTCPPCRGICNCSYCRRRDGRCATGILIHLAKFYGYDNVKEYLESLQKQL
What is the function of this protein?
Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter.  Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells.  Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1 (By similarity).
What are the official names of this protein?
Cell division cycle-associated 7-like protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction (By similarity).
Protein: RL1_DESHD
Sequence: MAKVGKNYQEAVKAFDRAALHEPMEALAVVKKIAKAKFDETVEVAFKLGIDTRHADQQIRGALVLPHGTGKTRSVLVFAKGDKAKEAEAAGADFVGAEDMIAKIEQGWFGFDVVVATPDMMGMVGKLGRVLGPKGLMPNPKTGTVTFDVAKAVKEIKAGKIEYRADKAGIIHAPIGKVSFSEEQLYQNYKVLVETLVKAKPAAAKGQYIRSVTVSSTMGPGVRINPVKAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: IDHC_MICME
Sequence: MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITFTPKDGSQKVTYLVHSFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase.  Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways (By similarity).  May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity).
What are the official names of this protein?
Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, IDH1, Cytosolic NADP-isocitrate dehydrogenase, IDPc, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PTN1_RAT
Sequence: MEMEKEFEQIDKAGNWAAIYQDIRHEASDFPCRIAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQKEEKEMVFDDTNLKLTLISEDVKSYYTVRQLELENLATQEAREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHVPPPPRPPKRTLEPHNGKCKELFSNHQWVSEESCEDEDILAREESRAPSIAVHSMSSMSQDTEVRKRMVGGGLQSAQASVPTEEELSPTEEEQKAHRPVHWKPFLVNVCMATALATGAYLCYRVCFH
What is the function of this protein?
Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response.  Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK.  May play an important role in CKII- and p60c-src-induced signal transduction cascades.  May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion.  May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET (By similarity).
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Interacts with EPHA3 at the cell membrane.
Protein: TRMFO_BRUSU
Sequence: MSNNTDLSPVHVIGGGLAGSEAAWQIAQAGVPVVLHEMRPVRGTDAHKTEQLAELVCSNSFRSDDAETNAVGVLHAEMRLAGSLIMACADAHQVPAGGALAVDREGFSQAVTARLEAHPLITIEREEITGLPPTEWGTTIIATGPLTAPSLAEAIAAETDADALAFFDAIAPIIHFDSINMDVCWFQSRYDKVGPGGTGKDYINCPMDKEQYEAFVAALIEGDKTDFKEWEGTPYFDGCLPIEVMAERGPETLRHGPMKPMGLTNAHNPTVKPYAVVQLRQDNALGTLYNMVGFQTKLKYGSQTGIFKMIPGLENAEFARLGGLHRNTYLNSPVLLDNVLRLKSRQTLRFAGQVTGCEGYVESSAIGLLAGRFTAAEKLSQAAVPPPPTTAFGALLGHITGGHIVTDDEPGKRSFQPMNVNFGLFPPVDVPKPEGKRLRGKEKTIAKKRALSARALADCRNWLSLY
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODAL_MOUSE
Sequence: MSAHSLRILLLQACWALLHPRAPTAAALPLWTRGQPSSPSPLAYMLSLYRDPLPRADIIRSLQAQDVDVTGQNWTFTFDFSFLSQEEDLVWAELRLQLPGPMDIPTEGPLTIDIFHQAKGDPERDPADCLERIWMETFTVIPSQVTFASGSTVLEVTKPLSKWLKDPRALEKQVSSRAEKCWHQPYTPPVPVASTNVLMLYSNRPQEQRQLGGATLLWEAESSWRAQEGQLSVERGGWGRRQRRHHLPDRSQLCRRVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVDNGRVLLEHHKDMIVEECGCL
What is the function of this protein?
Essential for mesoderm formation and axial patterning during embryonic development.
What are the official names of this protein?
Nodal.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: BCHZ_RHOCB
Sequence: MFLLDHDRAGGYWGAVYTFCAVKGLQVVIDGPVGCENLPVTSVLHYTDGLPPHELPIVVTGLGDAELGREGTEGAMSRAWKTLDPLLPSVVVTGSIAEMIGGGVTPQGTNLQRFLARTIDEDQWQCADRAMTWLFTEYGMTKGRMPGERMRPDGAKPRVNILGPMYGAFNMASDLHEIRRLVEGIGAEVNMVFPLGTHLSEVRNLVNADVNVVMYREFGRNLAEILGKPYLQAPIGLESTTKFLRSLGELLGLDPEPFIEREKHATLKPLWDLWRSVTQDFFATASFGICATETYARGIKAYLEGDLGLPCAFAVARKAGEKTKSDEVRGLIRQTRPLVVFGSINEKIYLAETKAGHGPAASFVPASFPGAAIRRATGTPFMGYMGSVYLLQEICNGLFDALFNILPLASEMDSAAATPATLRRDMPWDADAQAALDRIVSQHPVLTRISAAKSLRDAAEKAALDQGAERVVLEMVEALGDATMDRKGGN
What is the function of this protein?
Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.
What are the official names of this protein?
Chlorophyllide reductase subunit Z, Chlorin reductase subunit Z.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: GLMU_PSESM
Sequence: MSLDIVILAAGQGTRMRSALPKVLHPVAGNSMLGHVIHSARQLSPVGIHVVIGHGADAVREQLAADDLNFVMQDKQLGTGHAVAQALPALTAETVLILYGDVPLIEVETLQRLLKRVTPEQLGLLTVKLDDPTGYGRIVRDDQHRVCAIVEHKDATDAQKAITEGNTGILAVPASHLQDWLGRLSNNNAQGEYYLTDVIAMAVNDGLVVATEQPHDAMEVQGANDRKQLSELERHYQLREARRLMAAGVTLRDPSRFDVRGEVSVGRDVLIDINVILEGKVIIEDDVVIGPNCVIKDSTLRKGVVVKANSHIDGALLGECSDAGPFARLRPGSVLGAKAHVGNFVELKNANLGEGAKVGHLTYLGDAEVGARTNIGAGTITCNYDGANKHKTTLGADVFIGSNNSLVAPVDILDGATTAAGSTITQNVPAEQLGVARARQRNIEGWKRPVKITKD
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_CALS4
Sequence: MYRIAVLPGDGIGPEVIEEGLKVLKAVEEKYGLRFDIKKYPFGGEAIDKYGEPYPEETRNGCLSSDAVLLGAVGGPKWDGLEGDKRPEAGLLALRKSLGVYANLRPAVLYPSLKDASPLKNELLEKGLDILVVRELTGGIYFGPRGKEAIGYGFRAYDTEVYETQEIERIAVIAFEAALRRRKKITSVDKANVLESSRLWRKTVEEVAKRYPEVELNHMYVDNCAMQLVKNPFQFDVILTNNMFGDILSDEAAQIVGSIGILPSASLRGDRVGLYEPIHGSAPDIAGKKIANPLATILSVAMMLQYSFGEEEAAQDIRKAVERALEEGFRTADLGKGIVLSTEEMGDKVVEYIKG
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_SACD2
Sequence: MTIKVIEGDFKASTGKYALLVSRWNSFVVEHLKDGAIDTLRRHGISDENIEVIYAPGAFEFPLAAQKLADAKRYDAIIALGAVIRGGTPHFDYVAGECTKGLAQVSLNAGLPITFGVLTVDSIEQAIERSGTKAGNKGAEAASTALEMVSLISKI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SECB_JANMA
Sequence: MADENLQPLFQIQRVYLKDLSLEQPNSPAIFLEQEQPTIEVAVDVGAQPLAEGIFESTVTITVTAKIADKIAFLVEGKQAGIFEIRNIPDEQLDPLLGIGCPNVIYPYLRANIADAITRAGFPPVHLSEINFEVFYQQRLEALAQQQADNSSGIVMADGSAARH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMRL1_BOVIN
Sequence: MADKKLVVVFGATGAQGGSVARTLLEDGTFRVRVVTRDPGQRAAKQLRLQGAEVVQGDQDDEASMELALSGAHATFIVTNYWENCSQEQEVKQGKLLADLAKRLGLRYVVYSGLENIKKLTAGRLTVGHFDGKGEVEEYFRDIGVPMTSVRLPCYFENLLSYFLPQKAPDGRSYLLSLPMGDVPIDGMSVADLGPVVLSLLKTPEEYVGRNIGLSTCRHTVEEYAALLTKHTGKAVRDAKTSPEDYEKLGFPGAQDLANMFRFYALKPDRNIELTLKLNPKARRLDQWLEQHKEDFAGL
What is the function of this protein?
Redox sensor protein.  Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels.  At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis.  Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis.  Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1.  The homodimer binds one molecule of NADPH.  Has higher affinity for NADPH than for NADP(+).  Binding to NADPH is necessary to form a stable dimer (By similarity).
What are the official names of this protein?
NmrA-like family domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Under normal redox growth conditions localizes in the cytoplasm and perinuclear region. Nuclear localization is promoted by increased intracellular nitric oxide and reduced NADPH/NADP(+) ratios (By similarity).
Protein: METN_STRPC
Sequence: MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYSGAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKVQLSANALRQKRRDIGMIFQHFNLMAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAIARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICNRVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANALLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENILAAEKALHEAGVDVSILKRGA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MSCL_STAA2
Sequence: MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIGKIFGSVDFAKEWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKEEAEEEAVVEENVVLLTEIRDLLREKK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ETS1A_XENLA
Sequence: MKAALDLKPTLSIKTEKEYEAYSCSDMECADVPLLTPSSKEMMSQALRATFSRFTKEQQRLGIPIDPREWTDMHVREWVSWAVNEFTLKGVDFQKFCMSGAALCALGKECFLELAPDFVGDILWEHLEILQKDSKQYQTSEITPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPLGLLRDPLQPESLQGDYFTIKQEVVTPDNMCLGRISRGKLGGQESFESIESHDSCDRLTQSWSSQSSYNSLQRVPSYDSFDSEDYPPAMPSHKSKGTFKDYVRDRAELNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYVPEELHAMLDVKPDTDE
What is the function of this protein?
Transcription factor.  Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts.
What are the official names of this protein?
Protein c-ets-1-A, C-ets-1A.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS2_SHEON
Sequence: MSTQTNTKSDFSELDWDKQDGLIPAVIQNHLSGKVLMLGYMDKAALEQTLATGDVTFFSRSKQRLWTKGETSGHTLKLVAIDKDCDNDSLLVQVLPNGPTCHKGTESCWLDGNAHPFLNNLAELIASRKGQSPESSYTASLFARGTKRIAQKVGEEGLETALAAATHDKEELVNEASDLMYHLLVLLEDQALSLSDITANLLARHQKAQRK
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_CLOBA
Sequence: MKKGLTLDLSKTQAFVKDYELDYMEGMVKDSHDRLHSKTGQGNDFLGWIDLPVDYDKEEFARIKKAAEKIQSDSDVLVVIGIGGSYLGARAAIEMLTSNFHNVLDDNKRKVPKIFYAGNNISSTYMAELLEAIDGKDVSVNVISKSGTTTEPAIAFRIFKSYLEKKYGVEEARKRIYATTDKSRGALKSLADAEGYETFVIPDDVGGRFTVLTPVGLLPIAVAGINIDEMMQGAADARESYSNPSLKENDCYKYAVTRNALYNKGKEIEVLVNYEPCIHYFNEWWKQLYGESEGKDKKGLFPAAVDFSTDLHSMGQYIQDGRRNLFETVINVEKARKEITIEFSEGDLDGLNFLTGKTMDFVNNKAFQGTLLAHNDGEVPNMVLNVPELSPYYFGHMVYFFEKACGISGYLLGINPFDQPGVEAYKKNMFALLGKPGYEDMKDELEKRL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_PROM3
Sequence: MNTSRSQAIFSAAQRLMPGGVSSPVRAFRSVGGQPIVFDRVKGAYAWDVDGNRFIDYIGSWGPAICGHAHPEVIAALQDALEKGTSFGAPCELENQLAEMVIDAVPSVEMVRFVNSGTEACMSVLRLMRAFTGRDKLIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPRSTTSNTLTAPYNDLEAVKELFAENPDAISGVILEPVVGNAGFITPEPGFLEGLRELTREHGALLVFDEVMSGFRISYGGAQARFGVTPDLTTMGKVIGGGLPVGAYGGRAEIMEMVAPAGPMYQAGTLSGNPLAMTAGIKTLELLKQEGTYERLESTTERLINGILEAAKAAEVPITGNSIGAMFGFFLCEGPVRNFEDAKATDAERFGKLHRAMLERGIYLAPSAFEAGFTSLAHSEADIETTLKAFRESFAAVA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_DESVV
Sequence: MTKEFNYGTGRRKTATARTRLYPGTGVIEINGRPYEEFFPRKTLQMIIRQPLVLTKMLEKFDVKVNVAGGGISGQAEAVRHGISRALLELDAELRPVLKRAGFLTRDARKKERKKYGLRAARARYQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: MRE11_PYRHO
Sequence: MKFAHLADVHLGYEQFNKPQRAEEFANTFKKALEMCVKESVDFIIIAGDLFNSSRPSPGTIKTAIKLLQIPKENNIPVFAIEGNHDRTQRGPSVLHLLEDLGLLYVIGLRQERVENEYLTSERVGNYWLVKGVYDNLEIHGMKYMSSAWFEANLNFFKGIFRPDEDAILVLHQGIRDITEKVFPSYSAELKLSDLPRGYLYYALGHVHKRFETNYGDSPVVYPGSLERWDFGDYAKRLVWNGVTFREEVGSDKGFYIVEDFTPRFVNIKVRDFIDVVIKGDSEREIKKAVKASLPHIPRNSYVRFNIKWRKPFDVEWIKEIVNAEYLRIHTAIIKDEKSMNGESVDIKSFFTEQEWKVIDLASSDEFESYIEKIVDILSGYEKKEEREKKESKIRKFERPKNPGDLTAWLRGG
What is the function of this protein?
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair.  The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA.  Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.
What are the official names of this protein?
DNA double-strand break repair protein Mre11.
What is the protein family that this protein belongs to?
Belongs to the MRE11/RAD32 family.
Protein: RS24_BOVIN
Sequence: MNDTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAGKKK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.