PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_CLOD6
Sequence: MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQLLDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGALLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSSEAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFEGTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGDTITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAETSAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPANLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDERRVMLHYDLPLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETRAFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRKKKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IMUB_CAUVN
Sequence: MGLFPGQKAADALALVPDLVTADHDPAADRAALEALCDWCVRFSPAVAIDGDDGLFLDITGTDHLWGGEAAMLVDLVSRLARWGVPARAAIADTAGAAWALARFGPDLAIAPPGEQTAAIATLPVAALRLGDAAEAQLPRLGLHRVGQVLALPRAQLAKRFGLAAVLRLDQALGAASEALTFRRPASPWFDRLAFFEPISAPEDLARVAADALALICARLEAEGRGAKRFEVVFHRLDGRAFPVRVGLARIGRDAQRLARLVKPKLDMVDPGFGIEVVTVHAFAVEPMAAAQARLDADAAASADETLAPLIDRLVNRLGENRVWRADPFESHVPERSVVRVGPLDPPPAARWDPDRPRPVRLFKRPEAIVAIAAELPDYPPRLFTWRGRSHRVRRAEGPERIGQEWWRVGVEKGQTGPGKIRDYYRVEDDTGGRFWIFRQGLYGGEDAPKWWIHGLFG
What is the function of this protein?
Along with DnaE2 and ImuA is required for the error-prone processing of DNA lesions.
What are the official names of this protein?
Protein ImuB.
Protein: LSG1_DROME
Sequence: MGKKNKGGAPNLGRQLIKDRFGHTQRRKVDNDTMLHTTELQDGYDWGRLNLSSVTEESSFQAFLRTAELAGTEFQAEKLNITFVNPKQRVGLLSKTQEQRMHQKHDEHRDQLKIPRRPKWTKETSAEELVRAENEAFLDWRRDLALLQEDEEILMTPYEKNLEFWRQLWRVVERSDVVVQIVDARNPLLFRSADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTAFYSATLVEEELKREAEECLDSFPEVQQLRRAVEEIKQSLDSVEDALNVIEQKYKTIPETQNDELPRLPGDKNSPRLLSRLELIEFLRNIYTGPRHTEQHVTVGMVGYPNVGKSSTINSLMTVKKVSVSATPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPIDQMRDHVPAVNLLCERIPRHVLEDKYGIVIAKPLEGEDMERPPHSEELLLAYGYNRGFMTSNGQPDQARSARYVLKDYVNGRLLYAMSPPSVPQTEYHTFPERQRRVIEESQLPGQQQRAMRINKSTSKELDNQFFSDKPTHAHVKGRTNFPNVRLANDGSLVAGNDPAAKPWRHVKKERREKLRKKFSHLDEH
What is the function of this protein?
GTPase required for the nuclear export of the 60S ribosomal subunit.  Probably acts by mediating the release of Nmd3 from the 60S ribosomal subunit after export into the cytoplasm.  Regulator of body size; acts in serotonergic neurons to regulate insulin signaling and thus exerts global growth control.
What are the official names of this protein?
Large subunit GTPase 1 homolog, Nucleostemin-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. LSG1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Punctate distribution.
Protein: SECA_YERPY
Sequence: MLIKLLTKVFGSRNDRTLRRMQKVVDVINRMEPDIEKLTDTELRAKTDEFRERLAKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALSGRGVHVVTVNDYLAQRDAENNRPLFEFLGLSIGINLPNMTAPAKRAAYAADITYGTNNEFGFDYLRDNMAFSPEERVQRQLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYIRVNKLIPKLIRQEKEDSDSFQGEGHFSVDEKSRQVHLTERGLILIEQMLVEAGIMDEGESLYSPANIMLMHHVTAALRAHVLFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTIVVPTNRPMIRKDLADLVYMTEQEKIGAIIEDIRERTANGQPVLVGTISIEKSEVVSAELTKAGIEHKVLNAKFHAMEAEIVSQAGQPGAVTIATNMAGRGTDIVLGGSWQSEIAALEDPTEEQIAAIKAAWQIRHDAVLASGGLHIIGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKTTIDSYIPTQSLEEMWDIEGLEQRLKNDFDLDMPIAKWLEDEPQLHEETLRERILQQAIETYQRKEEVVGIEMMRNFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFAMFAAMLESLKYEVISVLSKVQVRMPEEVEALEVQRREEAERLARQQQLSHQTDNSALMSEEEVKVANSLERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CUTA_SALCH
Sequence: MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALIDCLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMF_PSEP1
Sequence: MTPNKPTLHPRNRHQGRYDFPSLIKAHPDLARFTITNPHGKPSIDFANPEAVRVFNRALLKAQYGIQHWDIPADYLCPPIPGRADYIHVAADLLADDNAGDVPRGTQVRALDVGVGANCIYPLLGHSDYRWRFLGSDIDPVALASAKAIVQANGLGKAITLRQQANRAHILSGLLQEGERFDLTLCNPPFHASRDEATRGSQRKWKNLGKQDPKRKLPVLNFGGQNNELWCEGGEIRFVTQLIGESVQYAERVLWFTSLVSKASNLPGIEAALKKSGAKAVRIIEMGQGQKQSRMVAWSFHDDAARQAWHAQRKSQA
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_XANCP
Sequence: MSHTPTPAAGSGHAPANGHMALVIGAIGVVFGDIGTSPLYTLKEAFSPHYGLTSDHDTVLGVLSLAFWALMITVTLKYVTIIMRADNEGEGGIMALMALTQRTLKQGSRSAYVVGILGIFGASLFFGDGVITPAISVMGAVEGLEIAAPSLHPFIVPITVVVLLVVFMVQRFGTEKVGKVFGPITCLWFLSLGAIGIWNIVDAPEVLKAFNPWWAIRFFMEHGWHGVFILGAVVLAVTGGEALYADMGHFGARPIRHGWYFFVLPMLLLNYLGQGALVLNHPAALKNPFFEAVPSWALYPMIILATLAAVIASQAVITGAYSVARQAMQLGYIPRMLIKHTSRDTIGQIYVPGINWLLMVMVIALVLIFRSSTNLAVAYGISVSMTMLIDTLLLALVARSLWPRWRNWVLPLCVVFFIIELAFVIANGAKLLQGAWFPLALGIVVFTLMRTWRRGRALLREEIRKDGIRIDSFLPGLMLAPPARVPGMAVFLTADPMVVPHALMHNLKHNKVLHERNIFLNVDTLPIPYAPADKRLQIESIGDEFYRVYVRFGFMETPDVPLALMRSCDQGGIHFDPMDTTFFASRETIVASANRGMPIWRDKLFALMHRNAAPATGFFRIPGNRLVELGAQVEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PP12_DROME
Sequence: MGDVMNIDSIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVAKFLQKHEFDLICRAHQVVEDGYEFFAKRMLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKRKK
What is the function of this protein?
Is essential for the regulation of mitotic chromosomal segregation as well as regulation of chromatin condensation during interphase.
What are the official names of this protein?
Serine/threonine-protein phosphatase alpha-2 isoform.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR44_BOVIN
Sequence: MASESDTEEFFDAPEDVHLEGGDPIGYPGKVGISALKETENSAYKVGNESTVQELKQDVSKKIIESIIEESQKVIQLEDDSLDSKGKGQSDQATASPVTAGTELSNIPGLLAIDQVLQEDSQKAESQDVSEETELESKQCFPSDDTCEKPVDETTKLTEISSTAQLNVPETVTEVLNKEEVEVKESDVLESASSHSLSTKDFAVVEEVAPAKPPRQLTPEPDIVASTKKPVPARPPPPANFPPPRPPPPSRPAPPPRKKKSELEFEALKTPDLDVPKENITSDTLLTTNMASESTVKDSQPSLDLASATSGDKIVTAQENGKAPDGQTIAGEVMGPQRPRSNSGRELTDEEILASVMIKNLDTGEEIPLSLAEEKLPTGINPLTLHIMRRTKEYVSNDAAQSDDEEKLQSQQTDTDGGRLKQKTTQLKKFLGKSVKRAKHLAEEYGERAVNKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLNSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFNYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKSEGNEKGEDAEVLETMPSGIMKTDNTEVLLSADFTGAIKVFINKRKNLS
What is the function of this protein?
Downstream effector for RAB11.  May be involved in vesicle recycling.
What are the official names of this protein?
WD repeat-containing protein 44, Rab11-binding protein, Rabphilin-11.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, perinuclear region. Endosome membrane. Golgi apparatus, trans-Golgi network. Note=Colocalized with RAB11 along microtubules oriented toward lamellipodia.
Protein: CMOB_CAMHC
Sequence: MNENEKKLLSDIECLPNVDCKCDFGDIVRAFADYKINDELKFKVRQIALNLRPWRKGPFEILETFIDSEWQSFMKFNLLKPFMDLQGKKVADIGCNNGYYLFRMSNLGAKKLIGFDPGVRTFLQFRFLEHFLKSGVIYELLGVENLPDYGEKFDSIFCLGVLYHRSDPVRALKELKSSLNSGGEVFLDTMFIDGDDEICLFPRLSYAKISNIYFLPTIRTLQNWCERAKFKDFEILAVKATDENEQRKTDWIYGQSLGDFLDPFDKTRTIEGYPAPKRVYVRVKI
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: GATA_NITEC
Sequence: MLNASLRQLSSLLSEKKISSTELTGEFLARIKALNPDLNAFITMDEEKSLDQARTADEMIATGQSTLLTGIPIAQKDIFCANGWLTTCGSKMLSNFISPYDATVVKQFDQVGMVNLGKTNMDEFAMGSSNETSYYGPVKNPWDRLAVPGGSSGGSACAVAARLAPAATGTDTGGSIRQPAALCGISGIKPTYGLVSRYGMIAFASSLDQAGPMARSAEDLALLLNVMVGFDERDSTSLQREKEDYTQDLEKPVSGLRIGLPKEFFAEGMSSDVSSAVEAALAEYRKLGATFVEVSLPNSKLAVPVYYVLAPAEASSNLSRFDGVRYGHRAAQYANLEDLYAKTRAEGFGDEVKRRILIGTYVLSHGYYDAYYLQAQKLRRLIAEDFKKAFEQCDLIMGPTSPTVAFNIGERCNDPIQMYLSDIYTSAASLAGLPGMSIPVGFGSKNRPVGLHIIGNYFREAQMLNAAHRYQLATNWHELTPPEMNR
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: LFTR_SALNS
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQHGIFPWFSPGDPILWWSPDPRAVLWPEKFHLSRSMKRFHNASPYRVTLNYAFDRVIDGCANHRDEGTWITRGIEEAYRRLHELGHAHSIEVWRDRELVGGMYGVSQGALFCGESMFSRQENASKTALLVFCAEFIRHGGKLIDCQVLNSHTASLGAIEIPRRDYLDHLAALRQQPLASRFWVPRTLFLPRK
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH3L3_BOVIN
Sequence: MSGLRVYSTSVTGSREIKSQQSEVTRILDGKRIQYQLVDISQDNALRDEMRALAGNPKATPPQIVNGDQYCGDYELFVEAVEQNTLQEFLKLA
What is the function of this protein?
Could act as a modulator of glutaredoxin biological activity (By similarity).  May play a role in cytoskeleton organization (By similarity).
What are the official names of this protein?
SH3 domain-binding glutamic acid-rich-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the SH3BGR family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FAAH4_CAEEL
Sequence: MGNNFWSTWSPSQRIFSLIWPATILYLIMKLLIEKMWGKNRGAVERFQTRREALFDDFKSRSAPASLVNNPRIVKGNETAEQIETTFNEILKLDLIALKSALQTDKYNAYTVLCAFVWRAIDVNSEINCITEVIREAFNTAEALDDNYAQTGEKGQLFGLPFSVKSNFYMENYDVTVGLAKLLEQPKTTTCPMVQFLSDQGAVPFCLTNVPQGLLSYVSSNPIYGTTKNPWDFSRTPGGSSGGEAALLAAGGAAFGIGSDLAGSLRIPAAFCGLVTLKPTQDRLCVTDTHGGLPGRGRLGLSFGFYTRSVKEQEFLLGLIVGRSEYLELCPMSSPAKLEKHIEKDQKLVIGWFVDDGFNPVVPSNRRAVEETVKSLQAKGHQVVELKLADVSEEFPPFAVADMLFRNVMPDNGAYMSEMYAGEQYDEHMKLFIRLVCLKQNFLVSFLLRYGVMPFAKLALSKRLACIGSAYNSDLAACRQNQENTDSYKLQWIRYWKSKKIDALICPSFITPAQPFEYPAQLSNGAFITGLFNMLDVPAGVVPVSPVNQKDVDQLIDGFSTEGDLLLKKQREAARGTTGLPNAVQVVTLPNCEEMCLRVMRLVEESAEGVQRLQWRVGASAAPIDVENTPAGVVSSLEHFERVNLLH
What is the function of this protein?
Converts monoacylglycerides to free fatty acids and glycerol (PubMed:30911178).  Hydrolyzes the endocannabinoid 2-arachidonoylglycerol (2-AG), and thereby regulates the degradation of endocannabinoid-related monoacylglycerides (PubMed:30911178).  Also hydrolyzes arachidonoyl ethanolamide (anandamide, or AEA), but with low efficiency (PubMed:30911178).  Plays a role in the regulation of longevity and resistance to oxidative stress (PubMed:30911178).
What are the official names of this protein?
Monoglyceride lipase faah-4, Fatty acid amide hydrolase 4.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: CABS1_MOUSE
Sequence: MAEDGSPKIYSRPPRDNSKTPTEADIFFGADNTIPKSETTITSEGDHVTSVNDCTPDGDFSTTVNKLTPTKEKLKLEDDIEGCLKLTTLPEKEITTPTETPNSKPKGSITENFIPVKIGNTSSPVGTVSLIDFSSNTAKEDIFLTTIDTGEKEVVPTTEFSGTLEDSAADVEDASGFPDESTETDVPSSATSDAPDDGAVQVTDSFSPEAGVPPSTEKEVTTIPDITNIAEENVTEIKLIVSEDRPKTVTKLSDSEEEKFITVFELTNSAEKAKDNVEDPLNDEESTDGANDWMEKETASEAESHAVLLTAVESRYDFIVTASETDNVMEESHVNTTDLPENETTESVTNVTEELPSVTSIVDTLKDKEDLSTTNSGLFKLLKEEPDDLMM
What is the function of this protein?
Calcium-binding protein (PubMed:19208547).  Essential for maintaining the structural integrity of the sperm flagella (PubMed:33440775).
What are the official names of this protein?
Calcium-binding and spermatid-specific protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion inner membrane. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mostly cytoplasmic, but associated with the mitochondrial inner membrane during the last steps of spermatid differentiation (By similarity). Localizes to the principal piece of the sperm flagellum (PubMed:19208547, PubMed:33440775).
Protein: SSRP_STRPZ
Sequence: MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARIQLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSGMTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MENC_ECOLI
Sequence: MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELTDTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRDRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:10194342, PubMed:8335646).  Does not show detectable N-acylamino acid racemase (NAAAR) activity with N-acetyl-S-methionine as substrate (PubMed:10194342).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: RL30_SYNC1
Sequence: MAGQIKVTLKKSGIGRKEYFTKVLKGLGLTKLHKTVVLTDTPEIRGMIRKVSHMVVVED
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RL20_RALSO
Sequence: MPRVKRGVTARARHKKVIDAAKGYRGRRNNVYRIAKQAVMRAGQYAYRDRRNKKRVFRALWIARINAGAREHGLSYSKFMNGLKKASIELDRKVLSDMAIHDKVAFAAIVNQVKANVA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NLTP1_ORYSI
Sequence: MARAQLVLVALVAALLLAAPHAAVAITCGQVNSAVGPCLTYARGGAGPSAACCSGVRSLKAAASTTADRRTACNCLKNAARGIKGLNAGNAASIPSKCGVSVPYTISASIDCSRVS
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 1, LTP 1, PAPI.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: ASSY_SALA4
Sequence: MTTILKHLPAGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHSHGRQLGKLLYQGRWFDSQALMLRDGLQRWVASQITGEVTLELRRGNDYSILNTVSDNLTYKAERLTMEKGESVFSPDDRIGQLTMRNLDITDTREKLFGYAKAGLLTASSATGLPQVENLENKGK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR4_ALIF1
Sequence: MRILRGSPALSEFRVNKLLELCRELSLPVTGIYAEFAHFADVTAELDASEVQKLEKLLTYGPTIEEHEPEGLLLLTTPRPGTISPWSSKSTDIAHNCGLDKIARLERGTAFYIERSEELSELQLIELKAILHDRMMEVVFTDFESASALFAVSEPAPYTEVDLLTGGRKALEDANVTLGLALAEDEIDYLLESFTEKLERNPTDIELMMFAQANSEHCRHKIFNADWTIDGVKQEKSLFKMIKNTFEVTPDNVLSAYKDNAAVMTGSEVGRFFPDPETRQYNYHQEKTHILMKVETHNHPTAISPWPGASTGSGGEIRDEGATGIGGKPKAGLVAFSVSNLKIPNFVQPWETDFGKPSRIVTALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVNSHAGEEVRGYHKPIMLAGGLGNIRDEHVQKKEIPVGASLIVLGGPAMNIGLGGGAASSMDSGSSSEDLDFASVQRENPEMERRCQEVIDRCWQLGDANPIAFIHDVGAGGISNALPELVDDGERGGIFNLRDVPNDEPGMSPLEIWCNESQERYVMAVADKDMATFDAICKRERAPYAVVGKATEERELKLEDSHFDNTPIDMPMDILLGKTPKMHRDAKTLKANNPAIDRSGIEMNEAVDRVLRLPTVAEKTFLITIGDRSVTGLVARDQMVGPWQVPVANCAVTAASYDSYHGEAMSLGERTPVALLDFGASARLAVGEAITNIAATNIGDIKHIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTKWEENGEQKEVTSPLSLVITAFARVEDVRKTITPQLRTPDNLEGLGDTSLVLIDLGNGKNRLGATALAQVYKQLGDKPADVDNAAQLKGFYEGVQALVANDQVVAYHDKGDGGLFVTLAEMAFAGHCGVNANIEALGEDTLAALFNEELGAVIQVRNDDLDAVLSTLAANGLEACSHVIGSVEASDELVIKSGESVVIERNRTELRTIWAETTHKMQGLRDNPACADQEHEAKKDNSDPGLNVKLSFDVNEDIAAPFINTGAKPKMAILREQGVNSHVEMAAAFDRAGFEATDIHMSDILTGQAVLEEYNGLVACGGFSYGDVLGAGEGWAKSVLFNDSTRDQFENFFKREDTFSLGVCNGCQMLSNLRDLIPGAEYWPRFVRNESERFEARFSLVEVQKSDSVFFNGMEGSRMPIAVSHGEGRVEVRDNDHLNAIENSGTVALRYVDNHGNPTQQYPNNPNGSPNAITGLTTTDGRVTIMMPHPERVFRTVANSWSPEGWGENGAWMRMFQNARKNIG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_SYNJB
Sequence: MLKREEVQHVAHLARLELTEEEEIQFTEQLTDILAYVEQLKELDTEGVEPTFHVLDMELPTRPDEVEPYPDIEGILANAPDRADMFFKVPRILEGED
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RS18_LEPCP
Sequence: MPPPRGKFSKDRKTKRNQQSLLFKRKRFCRFTVTGVKEIDYKDLDVLRDFVGENGKITPARLTGTRAFFQRQLTTAIKRARFLALLPYSDQHKV
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SYM_COXB2
Sequence: MTTEKRQILVTAALPYANGPIHLGHMVEHIQADIWVRFQRLKGNDCLFICGEDAHGTAIMITAQKQGLPPEALVAKMHKEHARDLGGFLIEYDNFYTTHSPENRELAELIYTRLKDKGDIFAKTISQAYDPVKEIFLPDRFIRGTCPRCGAKDQYGDVCEVCGATYSPTELIDPVSALSGAKPIEKNSEHFFFSLNRYTQLLKKWIDAGHLQPQVANKLKEWFSEDLKPWDISRDAPYFGFEIPHAANKYFYVWLDAPIGYMASLKNLSKQRPSVNFDAYWKEGSQTELYHFVGKDIVYFHALFWPAMLSGAGFRLPTAIYVHGYLTVNGQKMSKSRGTFITAHHYLDHLSPEYLRYYYAAKLSAQVEDIDLNLDDFIQRVNADLIGKYVNLASRCAGFITKNFGGKLANELPELDLYESFLQTEQTITDYYESLNYSKAVRVIMSLADRANQYIDAKKPWALAKEINQEAQVQAVCTQGLNLFKILTTYLKPILPVTAKKVEQFLNCDELNFANLKTPLLDHSVNPFEPLMQRLLPETAAQLTHE
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.