PharMolix/UniProtQA huggingface dataset:
Protein: ELL_MOUSE
Sequence: MAALKEARSYGLSCGRVSDGSRVSVFHVKLTDSALKAFESYRAHQDSVSLRPSIRFEGSQGHISIPQPDCPEEVRAFSFYLSNIGRDSPQGSFDCIQQYVSSYGDVHLDCLGSIQDKVTVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYMGKKVQFRKPAPGAADAVPSRKRATPINLASAIRKSSGSGASSVVQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKDTLDSLLQQVASVNPKDGTCTLQDCMYKSLQKDWPGYSEGDRQLLKRMLMRKLCQPQNATTDSSPPREHGRSASPSQKRPTDFIDPLASKKPRISHFTQRAQPTLNGKLGAPNGHETLLPAPGPTPSDTLSSSHLPPRLEPPRTHDPLADVSNDLGHSTQDYKHQEATPAPAPHLGLPLLTDFPQAEQPTSSSHTHSRPKKKSKKHKDKERPPEERPPAPQPDAPTAPALPPDAPGLNGACDNEPTSSSETPDYLLKYPAISSSEQRQSYKNDFNAEYSEYRSLHARIEQITRRFTQLDAQLRQLSQGSDEYETTRGQILQEYRKIKKTNTNYSCEKRRCEYLHRKLAHIKRLIAEYDQRQLQAWP
What is the function of this protein?
Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.  Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription.  ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site.  Required to stabilize the pre-initiation complex and early elongation.  Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (By similarity).  Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968).
What are the official names of this protein?
RNA polymerase II elongation factor ELL, Eleven-nineteen lysine-rich leukemia protein.
What is the protein family that this protein belongs to?
Belongs to the ELL/occludin family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Nucleus, Cajal body. Note=Colocalizes with EAF2 to nuclear speckles. Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes (By similarity).
Protein: EF1G_CARAU
Sequence: MAAGTLYTYPENWRAFKAQIAAQYSGARLKIASASPAFTFGQTNRSPAFLSNFPLGKVPAYQGDDGFCLFESNAIAHFLSNDALRGSTPQASAQVLQWVSFADSEIIPPASAWVFPTLGIMQFNKQATEQAKEEVKRVLAVLNQHLNTRTFLVGERVSLADITVVCSLLWLYKQVLEPAFRQPYPNVTRWFLTCVNQPQFKAVLGEVKLCEKMAQFDAKKFAEMQPKKEAPAKKEKAGKEGGKQQQPQQEKKEKKKEEKKAAPAEEEMDECEAALASEPKAKDPYAHLPKSSFVMDEFKRKYSNEDTLTVALPYFWDHFDREGFSIWYAEYRFPEELTMSFMSCNLITGMFQRLDKLRKNAFASVILFGANNDSCISGIWVFRGQELAFTLSEDWQIDYESYTWRKLDVDSEECKTMVKEYFAWEGEFKHVGKSFNQGKIFK
What is the function of this protein?
Probably plays a role in anchoring the complex to other cellular components.
What are the official names of this protein?
Elongation factor 1-gamma, EF-1-gamma, eEF-1B gamma.
Protein: MTG8R_MOUSE
Sequence: MVGVPGAAAFQLGCEKRVPAMPGSPVEVKIQSRSSPPIMPPLPPINPGGPRPVSFTPTALSNGINHSPPTLNGAPSPPQRFSNGPASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDISPEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTSIASPADSSELLMEVHGNGKRPSPERRDENNFERDTVPPEPPAKRVCTISPAPRHSPALTVPLMNPGGQFHPTPPPLQHYTLEDIATSHLYREPNKMLEHREVRERHHNLSLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRFNENTELRKTGTELVSRQHSPGSTDSLSNDSQREFTSRPATGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQSLHGHSPHSQSRPLLPGGRGSARSADCSVPSPALDKTSATTSRSSTPASVTAIDANGL
What is the function of this protein?
Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes.  Via association with PRDM14 is involved in regulation of embryonic stem cell (ESC) pluripotency.  Involved in primordial germ cell (PCG) formation (PubMed:27281218).  Stabilizes PRDM14 and OCT4 on chromatin in a homooligomerization-dependent mannerCan repress the expression of MMP7 in a ZBTB33-dependent manner (By similarity).  Through heteromerization with CBFA2T3/MTG16 may be involved in regulation of the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes (PubMed:19799863).  Required for the maintenance of the secretory cell lineage in the small intestine (PubMed:16227606).  Can inhibit Notch signaling probably by association with RBPJ and may be involved in GFI1-mediated Paneth cell differentiation (PubMed:25398765).
What are the official names of this protein?
Protein CBFA2T2, MTG8-like protein, MTG8-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the CBFA2T family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAUA_ECOLI
Sequence: MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPAIIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFAKSAIDAQQPYIANPDVWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ
What is the function of this protein?
Part of a binding-protein-dependent transport system for taurine.
What are the official names of this protein?
Taurine-binding periplasmic protein, Sulfate starvation-induced protein 1, SSI1.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein SsuA/TauA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NES1_FRAAN
Sequence: MNVETKHTRTMGDIFVQHSQKLELLKTVLRNVAELDALEGLNMIDAVQRLGIDYNFQREIDEILHKQMSIVSARDDLHEVALRFRLLRQHGYFVPEDVFNNFKDSKGTFKQVLGEDIKGLMSLYEASQLGTEGEDILVEAEKFSGHLLKTSLSHLDHHRVRIVANTLRNPHHKSLAPFMARNFFVTSQATNSWLNLLKEVAKTDFNMVRSLHQNEIVQMSKWWKELGLAKELKFARDQPLKWYIWSMACLTDPKLSEERVELTKPISFVYLIDDIFDVYGTLDDLILFTEAVNRWEITAIDHLPDYMKICFKALYDMTNEFSSKVYLKHGWNPLQSLKISWASLCNAFLVEAKWFASGKLPKSEEYLKNGIVSSGVNVVLVHMFFLLGQNITRKSVELLNETPAIISSSAAILRLWDDLGSAKDENQDGNDGSYVRCYLEEHEGCSIEEAREKTINMISDEWKKLNRELLSPNPFPASFTLASLNLARMIPLMYSYDGNQCLPSLKEYMKLMLYETVSM
What is the function of this protein?
Involved in monoterpene (C10) and sesquiterpene (C15) biosynthesis.  Converts geranyl diphosphate (GPP) into S-linalool and farnesyl diphosphate (FPP) into (3S)-E-nerolidol.  Exclusively present and highly expressed in the fruit of cultivated (octaploid) varieties.
What are the official names of this protein?
(3S,6E)-nerolidol synthase 1, FaNES1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsg subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SSRP_DEIRA
Sequence: MRRVYTNRRAHHEYELLERFEAGISLTGSEVKSVRAGGVDFRDAFARINGSDVDLEGLYIPVYKEATYNNHEPRRKRRLLLHREEIEKLRRGLEQKGLTLVPTRLYQKGRYFKVELALARGKKLHDKRRADAERTVARELREL
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: BLCAP_RAT
Sequence: MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCSDSPLPESAHDPGVVGT
What is the function of this protein?
May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B.
What are the official names of this protein?
Bladder cancer-associated protein, Bladder cancer 10 kDa protein, Bc10.
What is the protein family that this protein belongs to?
Belongs to the BLCAP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AGP31_ARATH
Sequence: MGFIGKSVLVSLVALWCFTSSVFTEEVNHKTQTPSLAPAPAPYHHGHHHPHPPHHHHPHPHPHPHPPAKSPVKPPVKAPVSPPAKPPVKPPVYPPTKAPVKPPTKPPVKPPVSPPAKPPVKPPVYPPTKAPVKPPTKPPVKPPVYPPTKAPVKPPTKPPVKPPVYPPTKAPVKPPTKPPVKPPVSPPAKPPVKPPVYPPTKAPVKPPVSPPTKPPVTPPVYPPKFNRSLVAVRGTVYCKSCKYAAFNTLLGAKPIEGATVKLVCKSKKNITAETTTDKNGYFLLLAPKTVTNFGFRGCRVYLVKSKDYKCSKVSKLFGGDVGAELKPEKKLGKSTVVVNKLVYGLFNVGPFAFNPSCPK
What is the function of this protein?
Proteoglycan that may contribute to the strengthening of cell walls.
What are the official names of this protein?
Non-classical arabinogalactan protein 31, Hydroxyproline-rich arabinogalactan protein 31.
What is the protein family that this protein belongs to?
Belongs to the non-classical AGP family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RS27A_SOLTU
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGAKKRKKKTYTKPKKIKHKKKKVKLAVLQFYKVDDTGKVQRLRKECPNAECGAGTFMANHFDRHYCGKCGLTYVYNKAGGD
What is the function of this protein?
Ribosomal protein S27a is a component of the 40S subunit of the ribosome.
What are the official names of this protein?
Ubiquitin-40S ribosomal protein S27a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.
Protein: SAU61_ARATH
Sequence: MMNTKKLLKMAKKWQQRAALRRKRISFHRSTDTTSSSTAAEKGCFVVYTSDRIRFAFPISYLSNSVIQELLKISEEEFGIPTEGPITLPFDSVFLEYLIRLVQRRMDGDTEKALITSISSTRCSLPCSFQLQEHSSTRLVF
What is the function of this protein?
May promote auxin-stimulated organ elongation, such as hypocotyls, stamen filaments and petals.
What are the official names of this protein?
Auxin-responsive protein SAUR61, Protein SMALL AUXIN UP RNA 61.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y006_SIFVH
Sequence: MFTKRNKQKDNRRKNGKGVMQMIKEEIIKAFKKMHEQHPPRGEKTVYVTDLLHCVLRPEEEIPPIQLIRGTVIHEGIEKLLKHYSELEIEFEKEVKKQYGEYTLMGRLDGITKDGTIIEFKSVHVPPEFPYEQHIYQVLIYIHMTEAKQGIIVYIGSNEIEEFLIKRDKVGKIETWVVERMETGEITFAQYDINDEWIYKQIIAYVTKTLIAPFQECKFCKLNKSCKFSKIR
What are the official names of this protein?
Uncharacterized protein 6.
Protein: ARPC_PSEPU
Sequence: MTKSLLSLAVTAFILGGCSLIPDYQAPEAPVAAQWPQGPAYSPTQSADVAAAEQGWRQFFHDPALQQLIQTSLVNNRDLRVAALNLDAYRAQYRIQRADLFPAVSATGSGSRQRVPANMSQTGESGITSQYSATLGVSAYELDLFGRVRSLTEQALETYLSSEQARRSTQIALVASVANAYYTWQADQALFKLTEETLKTYEESYNLTRRSNEVGVASALDVSQARTAVEGARVKYSQYQRLVAQDVNSLTVLLGTGIPADLAKPLELDADQLAEVPAGLPSDILQRRPDIQEAEHLLKAANANIGAARAAFFPSISLTANAGSLSPDMGHLFSGGQGTWLFQPQINLPIFNAGSLKASLDYSKIQKDINVAKYEKTIQTAFQEVSDGLAARKTFEEQLQAQRDLVQANQDYYRLAERRYRIGIDSNLTFLDAQRNLFSAQQALIGDRLSQLTSEVNLYKALGGGWYEQTGQANQQASVETPKG
What is the function of this protein?
The outer membrane component of an antibiotic efflux pump.  Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline.  Is not involved in organic solvent efflux.
What are the official names of this protein?
Antibiotic efflux pump outer membrane protein ArpC.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: TE2_HASHE
Sequence: SCSSGCSDCNSDSCQCTLNQFTNSDSCCC
What are the official names of this protein?
Augerpeptide hheTx2.
What are the subcellular locations of this protein?
Secreted.
Protein: SYC_SHESA
Sequence: MPMLKIYNSITRQKQEFKPITPGKVGMYVCGVTVYDLCHIGHGRTFVSFDMIVRYLRYAGYEVNFQRNITDIDDKIIKRANENQEDCNTLTDRLIGEMHKDFDALNMIRPDFEPRATLHIAEIIDMVERLLARGHAYVAADGDVLFSVASFPEYGRLSGQNLEQLQAGARVEVDDNKQNPMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGLHFDIHGGGSDLQFPHHENEIAQSCCAHDTPYVNYWMHTGMVMVDREKMSKSLGNFFTIRDVLGHYDAETVRYFLLSGHYRSQINYSEENLKQARAALERLYTAIKDVDLTVTAAPAEEFVAKFKAAMDDDFNTPEAYSVLFDMVREINRLKTTDMAQASAMAVAMKQLADVLGLLHQAPDAFFKGEGSDDEVAEIEALIVERNRARAEKDWPAADVARNRLNELGVVLEDGPSGTTWRKK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMC5_XENTR
Sequence: MASSIWKGLVGIGLFALAHAAFSAAQHRSYMRLTEKEDETLPIDIVLQTLLAFIVACYGIVHIAGEFKDMDATSELRNKTFDTLRNHPSFYVFNHRGRVMFQPPESEDCHRIQAPFSSNSSLKLSKLESMHR
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (By similarity).  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.  May be involved in Mg(2+) transport (By similarity).
What are the official names of this protein?
ER membrane protein complex subunit 5, Membrane magnesium transporter 1.
What is the protein family that this protein belongs to?
Belongs to the membrane magnesium transporter (TC 1.A.67) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Protein: MURC_BACC1
Sequence: MTVYHFVGIKGTGMSSLAQILHDMKHTVQGSDYEKRFFTQTALEKRSISILPFDKSNVKEGQVIIAGNAFPDTHEEIVAAKELNIPVHRYHHFLGDLMNQYTSVAVTGAHGKTSTTGLLAHVMQGAHPTSYLIGDGTGHGVENSKYFVFEACEYRRHFLSYNPDYAIMTNIDFDHPDYFTDINDVFSAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDGTIFDVFVRNTYYDTFKITGYGNHSVLNALAVIALCHYENVDVEAVKHQLTTFEGVKRRFNEKPMGEQVIIDDYAHHPTEINATIEAARQKHPEREIVAVFQPHTFSRTEKFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDVLKKHKNGVLIFMGAGDIQKFEAAYVKEVQVAEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIC_SALPC
Sequence: MSITAKSVYRDAGNFFRNQFITILLVSLLCAFITVVLGHAFSPSDAQIAQLSEGEHLAGSAGLFELVQNMTPEQQQILLRASAASTFSGLIGNAILAGGIILMIQLVSAGHRVSALRAIGASAPALPKLFILIFLTTLLVQIGIMLIIVPGIIMAIVLALAPVMLVEEKMGVFAAMRSSMRLAWANMRLVAPAVIGWLLAKTLLLLFAPSFAVLTPNVGAVLANTLSNLISAVLLIYLFRLYMLIRQ
What are the official names of this protein?
UPF0259 membrane protein YciC.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARC_PSECP
Sequence: METPNQDSGRTPTEQSAANDLSVADRQVNILRDKLRHIDRQLAAATQNNTKLVSMLETAKAEILRLKNALDQEGQPPYSFGTILQLNPRRQPAPGNSGQAATEESADIFNAGRKMRVGLSPLVNINQLTVGQEVLLNEALLIVAGLGYERAGELATLKEMLGADRALVVGRADEERVVRLSGALLAQKLRVGDALSIDSRTGYALEKVPRSEVENLVLEEVPDITYEDIGGLGPQIEQIRDAVELPFLHPDLYREHGLKAPKGILLYGPPGCGKTLIAKAVANSLAARAAERSGNVDLKSYFLNIKGPELLDKYVGETERHIRLIFARAREKASDGSPVVVFFDEMDSLFRTRGTGISSDVETTIVPQLLSEIDGVERLDNVIVIGASNREDMIDPAILRPGRLDVKVKIHRPDAEAAADIFNKYITPDLPFHESDLAEHNGDVQATVDAMVQRTVEAMYSTDKSNEFLEVTYANGDTEMLYFKDFNSGAVVQNVVDRAKKYAIKDLLTSQQRGLRIEHLLRAVVDEFREHEDMPNTTNPDDWARISGKKGERITYIRTIVQGKAGQEPGKSIETTPTTGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: BL1S1_KLULA
Sequence: MMSNERTLLNQLIKSKTDTVGSEILKEIEGNDEYIKDVQLKKLKELHDKKFKEKGVTPLIRLYEKYNACALNDGDLQNWAELIDRDIRILEGTIKILEDESNEG
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLS1, BLOC-1 subunit BLS1, BLOS1-homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: MERD_PSEAI
Sequence: MNAYPVSRLALDAGVSVHIVRDYLLRGLLRPVACTPGGYGLFDDAALQRLCFVRAAFEAGIGLDALARLCRALDAADGDEAAAQLALLRQFVERRREALADLEVQLATLPTEPAQHAESLP
What are the official names of this protein?
HTH-type transcriptional regulator MerD, Mercuric resistance protein MerD.
Protein: ECA4_ARATH
Sequence: MGKGGEDCGNKQTNSSELVKSDTFPAWGKDVSECEEKFGVSREKGLSTDEVLKRHQIYGLNELEKPEGTSIFKLILEQFNDTLVRILLAAAVISFVLAFFDGDEGGEMGITAFVEPLVIFLILIVNAIVGIWQETNAEKALEALKEIQSQQATVMRDGTKVSSLPAKELVPGDIVELRVGDKVPADMRVVALISSTLRVEQGSLTGESEAVSKTTKHVDENADIQGKKCMVFAGTTVVNGNCICLVTDTGMNTEIGRVHSQIQEAAQHEEDTPLKKKLNEFGEVLTMIIGLICALVWLINVKYFLSWEYVDGWPRNFKFSFEKCTYYFEIAVALAVAAIPEGLPAVITTCLALGTRKMAQKNALVRKLPSVETLGCTTVICSDKTGTLTTNQMAVSKLVAMGSRIGTLRSFNVEGTSFDPRDGKIEDWPTGRMDANLQMIAKIAAICNDANVEKSDQQFVSRGMPTEAALKVLVEKMGFPEGLNEASSDGNVLRCCRLWSELEQRIATLEFDRDRKSMGVMVDSSSGKKLLLVKGAVENVLERSTHIQLLDGSTRELDQYSRDLILQSLHDMSLSALRCLGFAYSDVPSDFATYDGSEDHPAHQQLLNPSNYSSIESNLVFVGFVGLRDPPRKEVRQAIADCRTAGIRVMVITGDNKSTAEAICREIGVFEADEDISSRSLTGKEFMDVKDQKNHLRQTGGLLFSRAEPKHKQEIVRLLKEDGEVVAMTGDGVNDAPALKLADIGVAMGISGTEVAKEASDLVLADDNFSTIVAAVGEGRSIYNNMKAFIRYMISSNIGEVASIFLTAALGIPEGMIPVQLLWVNLVTDGPPATALGFNPPDKDIMKKPPRRSDDSLITAWILFRYMVIGLYVGVATVGVFIIWYTHNSFMGIDLSQDGHSLVSYSQLAHWGQCSSWEGFKVSPFTAGSQTFSFDSNPCDYFQQGKIKASTLSLSVLVAIEMFNSLNALSEDGSLVTMPPWVNPWLLLAMAVSFGLHFVILYVPFLAQVFGIVPLSLNEWLLVLAVSLPVILIDEVLKFVGRCTSGYRYSPRTPSAKQKEE
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to an endomembrane compartment.
What are the official names of this protein?
Calcium-transporting ATPase 4, endoplasmic reticulum-type.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: WFDC5_HUMAN
Sequence: MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPARGTAPGCPGQANSDLGSVALHLSWGPTERVHDGRPGALPAGQHYLYQRWFQPSDNHWPADTSLQPIHPWFLLLGVKVHSLSSEEGLCITPVLCTTAIRASHPS
What is the function of this protein?
Putative acid-stable proteinase inhibitor.
What are the official names of this protein?
WAP four-disulfide core domain protein 5, Putative protease inhibitor WAP1, p53-responsive gene 5 protein.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_VEREI
Sequence: MQLNPAEISELIKSRIEGLGVSADIRNQGTVVSVTDGIVRVHGLSDAMQGEMLEFPPTADGTPSFGLALNLERDSVGAVILGEYEHISEGGTVKCTGRILEVPVGPELIGRVVNALGQPIDGKGPINAKMTDVIEKVAPGVIARKSVDQPMQTGLKSIDSMVPVGRGQRELIIGDRQTGKTAVAIDAIINQKGQNMTCVYVAIGQKASSIKNVVRSLEQAGAMDYTIVVAASASESAAMQYVSAYSGCTMGEYFRDRGQDALIVYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEAFTKGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETSLFNAGIRPAINAGISVSRVGSSAQTNLIKNQSGGIRTDLAQYRELAAFAQFASDLDEATRKQLDRGARVTELLKQTQYSPLPISLMNATLFAVNKGFTDDIDVKKVLPFEHGFHQLLKTSHAALLETMEKNGAKWDVKPAKPDDSAEKQAFKKVCQDAEAELLAAATSFKKSFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CD4_MACFA
Sequence: MNRGIPFRHLLLVLQLALLPAVTQGKKVVLGKKGDTVELTCNASQKKNTQFHWKNSNQIKILGIQGSFLTKGPSKLSDRADSRKSLWDQGCFSMIIKNLKIEDSDTYICEVENKKEEVELLVFGLTANSDTHLLEGQSLTLTLESPPGSSPSVKCRSPGGKNIQGGRTLSVPQLERQDSGTWTCTVSQDQKTVEFKIDIVVLAFQKASSTVYKKEGEQVEFSFPPAFTLEKLTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLALEAKTGKLHQEVNLVVMRATQFQENLTCEVWGPTSPKLTLSLKLENKGTTVSKQAKAVWVLNPEAGMWQCLLSDSGQVLLESNIKVVPTWPTPVQPMALIVLGGVAGLLLFTGLGIFFCVRCRHRRRQAERMSQIKRLLSEKKTCQCPHRFQKTCSPI
What is the function of this protein?
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses.  In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex.  The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins.  Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs).  In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.  LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells.  In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway.  Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.
What are the official names of this protein?
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts.
Protein: PYRF_STRPZ
Sequence: MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGPDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAIKAVTPTGFNCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVATYQAIKAEWAG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.