PharMolix/UniProtQA huggingface dataset:
Protein: LPXB_ECO57
Sequence: MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDFNIILEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNSARDVLGIPYDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQFERIKAAVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RAB18_CAEEL
Sequence: MSDDSSSPLTTLKILIIGESGVGKSSLMLRFVDDVFDPEQAATIGVDFRVTSMAIDGNRVKLAIWDTAGQERFRTLTPSYYRGAQGVICVYDVTSRSSFEKLNHWMQEVDTYCTNDNIIKMMVANKIDMPNRVVTREEGLKFAKRHRTLFIEASAKTKEGVQCTFEELIEKIIQTPDLWDNDRPSFRLGQPTGSSGGGGMCGC
What is the function of this protein?
Plays a role in apical endocytosis/recycling (PubMed:24843160).  May be implicated in transport between the plasma membrane and early endosomes (By similarity).  Plays a role in the shedding of pathogen spores from intestinal cells (PubMed:24843160).
What are the official names of this protein?
Ras-related protein Rab-18.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: RS9_BURCJ
Sequence: MIGNWNYGTGRRKSAVARVFIKAGKGDIIVNGKPIADYFSRETSLMIVRQPLELTNHGQTFDIKVNVNGGGETGQAGAVRHGITRALIDYDATLKPSLSSAGFVTRDAREVERKKVGLRKARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: IFI6_PANTR
Sequence: MRQKAVSLFLCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALGFTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVITGNIGALMGYATHKYLDSEEDEE
What is the function of this protein?
Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis (By similarity).  However, it has also been shown to have a pro-apoptotic activity (By similarity).  May have an antiviral activity (By similarity).
What are the official names of this protein?
Interferon alpha-inducible protein 6, Interferon-induced protein 6-16, Ifi-6-16.
What is the protein family that this protein belongs to?
Belongs to the IFI6/IFI27 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ACCD_RHIEC
Sequence: MNWITNYVRPRINSMLGRREVPENLWIKCPETGEMVFHKDLESNKWVIPASGYHMKMPAKARLADLFDNGEYESLPQPKVAQDPLKFRDSKKYSDRLRDSRLKTEQEDTILAGLGKVQGLKLVAVVHEFNFIGGSLGIAAGEAIVKAFERATSEKCPLVMFPASGGARMQEGILSLMQLPRTTVAVDLLKESGQPYVVVLTNPTTGGVTASYAMLGDIHLAEPGAEIGFAGKRVIEQTLREKLPEGFQTSEYLLEHGMVDMVVKRHDIPETLARVLKILTKKPVSAANDVTRGAIALAASA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_HELP2
Sequence: MKERIVNLETLDFETSQEVSLRPNLWEDFIGQEKIKSNLQISICAAKKRQESLDHMLFFGPPGLGKTSISHIIAKEMETNIKITAAPMIEKSGDLAAILTNLQAKDILFIDEIHRLSPAIEEVLYPAMEDFRLDIIIGSGPAAQTIKIDLPPFTLIGATTRAGMLSNPLRDRFGMSFRMQFYSPSELSLIIKKAAVKLNQDIKEESADEIAKRSRGTPRIALRLLKRVRDFALVKNSSLMDLNITLHALNELGVNELGFDEADLAYLSLLANAQGRPVGLNTIAASMREDEGTIEDVIEPFLLANGYLERTAKGRIATPKTHALLKIPTLNPQTLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: EFG2_PSET1
Sequence: MADLSKYRNIGIFAHVDAGKTTTTERILKLTGQIHKSGDTHDGTSVTDFMDQESERGITIQSAAVSCFWKDHRFNVIDTPGHVDFTVEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYANESGVARVIFVNKLDRMGADFFRVTNQVQKVLGATPLIMTLPIGREDEFVGVVDVLTKQAYVWDATGLPENYTIEDVPADMVDQVEEYHELLIETAVEQDDELLETYMEGVIPSIEDVKRCIRKGTRDLAFFPTYCGSAYKNKGMQLILDAVVDYLPSPTEVDPQPLMDEEGNENGEFAIVSTDLPFKALAFKIMDDRFGALTFVRIYSGKLNKGDTILNAFTGKTERVGRMVEMQADDRNELASAQAGDIIAIVGMKNVQTGHTLCDPKHPVTLEPMVFPTPVISIAVQPKDKGGNEKMGVAIGKMVAEDPSFQVETDEDSGETILKGMGELHLDIKVDILKRTYGVDLIVGQPQVAYRETITKEIEDSYTHKKQSGGSGQFGKIDYRIKPGEVASGFTFKSSVVGGNVPKEFWPAVEKGFKSMMGTGVLAGFPVLDVEVELFDGGFHAVDSSAIAFEIAAKGAFRQSIPKAGAQLLEPIMKVDVFTPEDHVGDVIGDLNRRRGMMKDQEPGLTGVRIKVDVPLSEMFGYIGSLRTMTSGRGQFSMEFSHYAPCPNNVAEAVIAAEKEKKAAK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_THENN
Sequence: MRRRRAERRQIPPDPVYGDVLVAKLINKVMWDGKKTIAQKIVYGAFDIIKEKMKKDPLEVFRQAVENVKPVLEVRPRRVGGATYQVPIEVQEPRRTSLAIRWIVEAARAKKGRPMKEKLAEEIMAAYNNTGTAIKKKEDTHRMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MUTS_SALDC
Sequence: MNESFDKDFSNHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPHHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDGKGYGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMALIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENASRGLCAAGCLLQYVKDTQRTSLPHIRSITMERQQDSIIMDAATRRNLEITQNLAGGVENTLAAVLDCTVTPMGSRMLKRWLHMPVRNTDILRERQQTIGALQDTVSELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELHAQLETVDSAPVQALRKKMGDFAELRDLLERAIIDAPPVLVRDGGVIAPGYHEELDEWRALADGATDYLDCLEIRERERTGLDTLKVGYNAVHGYYIQISRGQSHLAPINYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYDELFDLLLPHLADLQQSANALAELDVLVNLAERAWTLNYTCPTFTDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALLAYIGSYVPAQNVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLAAPEEASPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PCS1_CAEEL
Sequence: MSQRRHFKMSVTAKNFYRRPLPETCIEFSSELGKKLFTEALVRGSANIYFKLASQFRTQDEPAYCGLSTLVMVLNALEVDPEKVWKAPWRFYHESMLDCCVPLENIRKSGINLQQFSCLAKCNRLKSTVSYGDNSPDFLKKFRTSLVNSVRSDDQVLVASYDRSVLGQTGSGHFSPLAAYHEDSDQVLIMDVARFKYPPHWVKLETLQKALCSVDVTTKLPRGLVELELKKGTRPLIMYGLKAYVNINDSDFATSVISWNQFLLCDPLEDDEEEFQLCCRKFGQCFAPHAMCCTQKTFDADQKNSCTECSTDQNEACKMICSEIRRTRFAEVFSSSAVAALLIAWPFEKGYSERSDRIGNLAEKYKNEFSAETMNEMNQLTTQIRTLISCSKPPVVININKPDATSNKCCKNKIGQSCACANDVNL
What is the function of this protein?
Involved in the synthesis of phytochelatins, which are heavy metal binding proteins required for the detoxification of heavy metals such as cadmium, arsenic and copper.
What are the official names of this protein?
Glutathione gamma-glutamylcysteinyltransferase, Phytochelatin synthase, PC synthase.
What is the protein family that this protein belongs to?
Belongs to the phytochelatin synthase family.
Protein: TILS_RICPR
Sequence: MLYEKFEYNINNLIGNFGLSKIAIAVSGGSDSISLLYLANIWARKNNIELFVISVDHNLRPQSKQENYYIHTISSNLNRKYYNLSFDHQNNFSNLQERAREGRYDLMTNLCLELDVLVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNIHWYNNIQIIRPLYNIPKSELVEYLVNHKIKWFEDESNLSDKYRRNIIRQKLFKEENYIKAEISLQQLKTNKLIEDELKPALISAIAEAVKIFEYGFTFLDLVKFDKFLNEVKAQIINFLLIMISGQSRSARFYSIAHILKLISQDINFKNTVHGCVIKRIQNELLIYREFGKKLPKSKILLDKSVIWDNRFCITKNQKTPDCVITYLSLADYKAIKKQLDLKHLKNLSCKNHNAILFTLPIIKILEKVIAIPHISYYDNDVWNFEVSFAPNFVSRFTHFC
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_LEUMM
Sequence: MANDVIEIEGKVKETLPNAMFQVELENGAVILAHVSGKIRKNFIRILPGDRVTVEMSPYDLTKGRITYRFR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOR3_ARATH
Sequence: MQIYNPISPVKTMVKIYPHLAFPVDMDVVQDKILPYLTTEQERFTIWMKSLVFNSKGCTVFDSKGNLIYRVDNYDSKSWSNEVYFMDLNGKILFTLRQKKLGFFKSWEGYNSTGTRFRLRKIFKILPRESSSSYKVVMGSRIVDGDQQSCYKIVNRGSVFAIKDGSGRLMAEVKNKLSDISGLDLGDDVLTMMVEPQLDHSLIMGIVIAYKLTKCKL
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 3.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: LYZL1_BOVIN
Sequence: MKAAGILALMGCLVTVVEPKVYTRCKLAKIFSRASLDNYRGFSLGNWICMAYYESHYNTTAQTQLEDGSTDYGIFQINSDTWCRSTKLQEKNRCHVACSALMTDDLTDAIICAKKIVKETDGMNYWQGWKKNCEGRDLSEWKKGCEVS
What are the official names of this protein?
Lysozyme-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCM1_XENLA
Sequence: MATGGGPPDEALSDQDLPNWSHESLDDRLNNMHWNGQKKGNRSAEKNKKKFVECDLRLTNDISPESSPGVGRRRARTPHTFPHTRYVSQMSVPEQAELEKLKQKINFSDLDQRSIGSDSQGRATAANNKRQLADNRKPFNFLPSQLNTNKEKSKSPPKREASTRSLTKDFLASALNKDFLSNSQAFLEEESKREPAIDSSQVVSRLVQIRDYITKASSLRDDLVQKKDLSVNVERLSNLIEHLKFQEKSYLKFLQKMLASENEEEDVRTVDSAVGSGSVVESTLLTFDVPSEASDTTGVDPRQEAKEELKNMKKQHALLTRMLQQQEQLRTLKGRQAALLALQHKAEQAIAKMDESVVTETTGSVSGLSLTSELNEELNDLIQRFHNQLHDSEDPPAPDNRRQAESLSLAREVYRSRNSSTSDTPLEDKSPLFNNVGVLLEKKQKMDTLLGELHTLQDQQLNNTAFVASSVSPRRSTEQRTLGSAVSSALTSDNRAARSPVTIGAYQTASVNESEDEENQNPAEKLKKLKEVRKRLNELRELVHYYEQTSDMMTDAMNENTKDEDETEDSEYDSEQEDAEPTTNIRNPQYRSSWAQMNINSNNQSGTNNRDERQLNTECEINNRSAVNLRSFNMPSALDCLYNIEHSDKEEDGNRELDDEDAEDQGSRASLSSQNSVADDVQSVDFEQKFNRLVAAKQKLKQLQDLVAMYGDDSESEPVAPERSFSGDQFPPEATTLKQQPNNTRPNVSKAQKDIALKEQAREKFYESKLQQQQRELSQLQEERKKLIEIQEKIQTLRKACPDLQLSTSSAGTNPANRQNRQMTTTTSTPDVNTNGNIVVPAMPDPEDSSSVDNEVWSEIRKHQILREDLRQRRKQLETLMAEHQRRQGNTETTSAASIRSDDSDTQGLQQQTRTEKTMATWGGSTQCALEEEEEEEEVDDEECLSDVHQIDIEEDEQDNTSCENNSYPQNSIRKTSFNGRSSKDGWKNQCPLSVEGNHRPSPKTRQQQNVSMRRQENYRWMSELSHVEEKEHWQEQIDQIKKQLDYSTSICQTLMRDQQALSYLLQSMITTPYSVMPSNVGASQVQLIMHQLNQCYTQLNWQQSNVLRLKQMLNDLLVQQPQHLQGESHQREDRGSSAPPLTSPNIFPNFSFLPPTMNLLNMPAFGSIPNVVPGMNFNPVFPHGFENFTQNVASHTDTPLQPHDQNTSGKTEYMAFPKPFESHRSNSTEKERNPPKKPDESEQGRRVWVENHQKSDQEKKPACFGAGLSAGGASAKLAEESRKVKQFDEVSVESLSSMPDPVDPTTVTKMFKSRKASAQASLASKDKTPKAKNKKRKVFHQKSKGIKSCGFQAASASSASEPNQTTCKHAQTEEVVVGNVIKTSSAQRVEKESKATEMSSEAGSDVSMFETLRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQKALFALQDIVTRHVSEGNAKKHETCTKALESTGWMASTSELTPSESLVTTDDEMYAKNSDGPVCQEGEQNDGDNISSLSTSSNFEPFATDDLGNTVIHFDQALARMREYERMKSETENGLVADCCNNLNAAASSLEGTNDEARGRAQHSVDDASGIPCPYIDSKQLDRQIKAIMKEVIPFLKEHMEEVCSPNLLTSIRRLVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFSSKKLKDCGEDLLVEISEVLFNELAFFRLMQDLDNNSTAVQGTVSRKPEAVVVLESFTKEADKEEKTCPEENFSATRETDDEDKDKDETETAEENRNFDAEVLSGKSDISEEDDLDESLPVSISFTKAETQALTNYGSGEDENEDEENYEFEARPVDVQTSLETSSEIADETEKEEMEVRPEANIENEKALSLAVNVMGELSIHEDQAKSDCDVLAHPSLLLSNEKATDFSGTALVNNVKSPVDSPGTSGAGSSDTESPVLVNDFETGSGNLSQKSDEDDFVKVEDLPLKLSLPQEQIMKDIEEEENKNNLCDEILNINDEENGADQLAGDPLALKEPDSPAIHPA
What is the function of this protein?
Required to anchor microtubules to the centrosome (By similarity).  Required for centrosome assembly and function.  Essential for the correct localization of several centrosomal proteins including cetn3 and pcnt (PubMed:12403812).  Probably involved in the biogenesis of cilia (By similarity).
What are the official names of this protein?
Pericentriolar material 1 protein, PCM-1, xPCM-1.
What is the protein family that this protein belongs to?
Belongs to the PCM1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic granule. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Note=Recruitment to the centrosome may require cytoplasmic dynein. The majority of the protein dissociates from the centrosome during metaphase. Also associates with microtubules.
Protein: ERP_MYCBO
Sequence: MPNRRRRKLSTAMSAVAALAVASPCAYFLVYESTETTERPEHHEFKQAAVLTDLPGELMSALSQGLSQFGINIPPVPSLTGSGDASTGLTGPGLTSPGLTSPGLTSPGLTDPALTSPGLTPTLPGSLAAPGTTLAPTPGVGANPALTNPALTSPTGATPGLTSPTGLDPALGGANEIPITTPVGLDPGADGTYPILGDPTLGTIPSSPATTSTGGGGLVNDVMQVANELGASQAIDLLKGVLMPSIMQAVQNGGAAAPAASPPVPPIPAAAAVPPTDPITVPVA
What is the function of this protein?
Surface-exposed protein required for multiplication and intracellular growth.
What are the official names of this protein?
Exported repetitive protein, Cell surface protein PirG, EXP53.
What is the protein family that this protein belongs to?
To M.leprae 28 kDa antigen.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: H32_XENTR
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: LTOR5_PIG
Sequence: MEATLEQHLEDTMKNPSIVGVLCTDSQGLNLGCRGTLSDEHAGVISVLAQQAAKLTSDPTDIPVVCLESDNGNIMIQKHDGITVAVHKMAS
What is the function of this protein?
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids.  Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag.  Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.  When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway.
What are the official names of this protein?
Ragulator complex protein LAMTOR5, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR5 family.
What are the subcellular locations of this protein?
Lysosome. Cytoplasm, cytosol.
Protein: BUD31_YEAST
Sequence: MPRIKTRRSKPAPDGFEKIKPTLTDFEIQLRDAQKDKSSKLAAKSNEQLWEIMQLHHQRSRYIYTLYYKRKAISKDLYDWLIKEKYADKLLIAKWRKTGYEKLCCLRCIQKNETNNGSTCICRVPRAQLEEEARKKGTQVSFHQCVHCGCRGCASTD
What is the function of this protein?
Involved in pre-mRNA splicing.  Important for bud site selection.
What are the official names of this protein?
Pre-mRNA-splicing factor BUD31, Bud site selection protein 31, Complexed with CEF1 protein 14.
What is the protein family that this protein belongs to?
Belongs to the BUD31 (G10) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCR5_YEAST
Sequence: MSSFGHRAFFSCCPLLEGETLHSIKLRKEATYQTQSGWPVRWPIRYPRALPLESHVHPYHMIVKLPHPRTQPRLFLWLSLHWTGIPFLGKPGIGRNRVKSKQFSHFQQSKIKTTMRKKTTNRKQKAERCQYRLVTA
What are the official names of this protein?
Uncharacterized protein YCR025C.
Protein: LUXS_YERE8
Sequence: MPLLDSFTVDHTIMKAPAVRVAKTMKTPHGDEITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVTDQRKIPELNEYQCGTYHMHSLEEAQEIAKGIIDRGVRINHNEELALPKEKLTELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RS20_STRT2
Sequence: MEVKTLANIKSAIKRAELNVKQNEKNSAQKSALRTVIKAFKANPTEEAFRAASASIDKAASKGLIHKNKASRDKSRLAAKLAN
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: HIS2_CHRVO
Sequence: MTPDVLKNIADTLEARREAAPQSSYVASLFHKGEDAILKKVAEEAAETLMASKDKDKLHLVREVADLWFHTMVLLTYHGLRPEDVVMELHRREGISGLDEKASRKPTA
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIS1_ARATH
Sequence: MAKKERPRPEKLSVYLYIPNIVGYMRVLLNCVAFAVCFSNKPLFSVLYFFSFCCDAVDGWVARRFNQVSTFGAVLDMVTDRVSTACLLVILSQIYRPSLVFLSLLALDIASHWLQMYSTFLAGKSSHKDVKDSTSWLFRLYYGNRIFMCYCCVSCEVLYIILLLIAKNQSENLLNVVVATLTQISPLSFLLALTLFGWSMKQTINVIQMKTAADVCVLYDIEKQQKP
What is the function of this protein?
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction.  May thus act to reduce an excessive cellular PtdIns content.  The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme.
What are the official names of this protein?
CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1, Phosphatidylinositol synthase 1, AtPIS1, PI synthase 1, PtdIns synthase 1.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TAL_SYNC1
Sequence: MKFFIDTADIDQIKAAHEMGLVDGVTTNPSLVAKTGRKFTDVLKDIVQLIDGPISAEVVATDAEGMIAEARELIQYHPTNIVIKIPMTGEGLKATRVLAKDGVRVNMTLIFSPLQALLAAKAGAAYVSPFVGRLDDVGHDGMEGVDEILTIFENYGFDTEIIVASVRSPQHVLRAGLQGAHICTIPYNVIMQLTKHPLTDVGIERFLADWKASQQ
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_ALBFT
Sequence: MRELEQALRGGLADLALVLEDRQIALLLDYLALIQKWTQVYNLTAVREPAEMLTHHLLDSLAVIQPLRRQLAGLRDQTPDTDTANVRLLDVGSGAGLPGVVIAICCPEITVDCVDTVAKKVAFIRQVAATLKLANLHGLHARVESLTGPYRVICSRAFASLADFTRLSSAALAPQGLWLAMKAKDPAEEVAALPATVKVFHVEHLVVPGLGADRCIVWMRQSAV
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.