PharMolix/UniProtQA huggingface dataset:
Protein: TIG_MESM1
Sequence: MTKTEINKKDWEINVVVSSEKKLWKAKQDLALSNLAKTLKIKGFRPGKASVEAAKKHLNPEQIQEEAVKLIANDLVKIASESIDESYIVLDSPIYEVEKMSDAELDLKFSYPIYPEFKIKNYKSLKVTLSRAKVSKEDVDSEIEKIREKNALLIKKTKDQGKVAKTDTVNIDYVGKIDGEEFDGGKASSHELVIGSKSFIDNFEDQLIGFKSGDKVEVKVSFPDDYHSSKFAGKKAIFDVKINDVFTKEKPVKNDDLVKFLNNPKLKTLAEMENYFKDLIKNEKDEKSKASFKKDIFEKIMNENEIPVPRLILMKETTNAIREFEKDVKKYGFTVEKYLKMLNMNSKDFVTNLNKESELKLKEALIYTEISKLEKIEAQPEDYDVKYKKFAKLYNVSLDSVKSMITQQQAQVAIVNEKILEFLIKHNAIEKNSVGEEPKLSTTKKVVEPTEEKTRKDSKMSTKKPAAKPAAKPAAATKKPVKK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
Protein: SYA_POLAQ
Sequence: MKVTQIRQAYLDFFAQKGHQIVPSSPVVPGDDPTLLFTNAGMNQFKDVFLGFDKRSYTRATTAQKCIRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKKDAIQFAWDLLTQVFELPKDKLLVTVYAEDDEAYAIWKDQIGVPAERIIRIGDNKGARYASDNFWMMGDTGPCGPCTEIFYDHGEHIPGGPPGSPDEDGDRFIEIWNNVFMQFNRDEAGVMHPLPKPSVDTGMGLERIAAVLQHVHSNYEIDLFVNLIKAAKDTVDGAGGENCDAQSPSLKVIADHIRACSFIVVDGVIPGNAGRGYVLRRIARRAIRHGYKLGARKPFFYQLVPALVKEMGDAYPELRAAQDKVSEVLKQEEERFFQTIANGMEILDGALAGGAKVVDGETAFRLHDTFGFPLDLTADVCRERGVTVDSEGFEVAMQKQRDQARAAGKFKVAQGLDYKGVPTRFHGYETLKHEGAKITALYLDGSAVNSVKAGDAAVVVLDNTPFYAESGGQVGDKGELRNEAARFTVDDTFKIQADVFGHQGEVLEGELKVGDTLNALVDIALRNDTMRNHSATHILHKALREVLGDHVQQKGSLVDASKTRFDFTHNAPITAEQIRRIEDIVNAEILDNSATSGKVMSLEDAQKTGAMMLFGEKYGDEVRVLEIGSSKELCGGTHVSRTGDIGSLKIVSEGGVAAGIRRVEAVTGQNALHFLQGLEDKINEAATILKTHPGDLVNRVAQLQESLRLAERELEKVNSKLAASQGDELAGQAIDVNGLKVLAARLDGADAGVLRETMDALKAKLKTAAIVLASVQGDKVSLIAGVTADSIAKVKAGDLVNFVAQQVGGKGGGKPEMAMAGGNDPSKLGAALDGVKDWVASK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_RHOE4
Sequence: MFVRRFSLRDFRSWDSLTLDLTPGTTVFLGSNGHGKTNVLESLGYLSTLSSHRVSTDAPMIRSGSASAFAGATVVNNGRELTIDVELIEGKSNRARINQSPTRRPREVLGILQSVMFAPEDLSLVRGDPGDRRRYLDELLTSRIPRMAAVRADYDKVLRQRSALLKTAGAALRRGSRGGESDNVLSTLEVWDGHLAAHGAQLLAGRLELVHDLAPHLAESYRSIAPESRPASIRYKSSLGSSLDPEFTDPARISGIDDVAYLEERFHLELAQMRSKEIDRGVCLVGPHRDDLELVLGDSPAKGFASHGESWSFALSLRLAGFALLRADGSDPVLMLDDVFAELDRRRRRALATVAATAEQVLITAAVPEDVPDELEAAKFGVEASDTGDGRISRIVPVGSTDQEVEFDD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA_YERPS
Sequence: MHNHNNRLVITPGEPAGVGPDLAIALAQQDWPVELVVCADPALLLARASQLNLPLQLREYQADQPAIAQQAGSLTILPVKTAVNVVPGKLDVGNSHYVVETLAKACDGAISGEFAALVTGPVQKSIINDAGIPFIGHTEFFADRSHCQRVVMMLATEELRVALATTHLPLLAVPGAITQASLHEVITILDNDLKTKFGITQPQIYVCGLNPHAGEGGHMGHEEIDTIIPALNTLRQQGINLIGPLPADTLFQPKYLQHADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVDHGTALELAATGTADVGSFITALNLAIKMINNSNE
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_STRPJ
Sequence: MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: NDHI_BARVE
Sequence: MLPMITGFMNYGQQTLRAARYIGQGFMITLSHTNRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETNIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYEFSTYDRHELNYNQIALGRLPMSVIDDYTIRTILNSPQTING
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RL40_METTP
Sequence: MARFSEAENRVLNVKICMRCNARNPIRATRCRKCRYKGLRMKSKESRG
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: SKDA1_MOUSE
Sequence: MGDLKSGFEEVDGVRLGYLIIKGKQMFALSQVFTDLLKNIPRTTVHKRMDHLKVKKHHCDLEELRKLKAINSIAFHAAKCTLISREDVEALYTSCKTERVLKTKRRRVGRALATKAPPPERAAAASPRPAFWKDKHQLWRGLSGAARPLPISAQSQRPGAAAARPAAHLPQIFSKYPGSHYPEIVRSPCKSSLNYETAQLQGNYVAFHSDPAYFRSLLCSKHPAAAGATCLERFHLVNSFCPPPHHHHHHHHHHHHHHHRAQQPTPSHHPSHHHRPQPHLGSFPESCSSDSESSSYSDHAANDSDFGSSLSSSSNSVSSEEEEEEGEEEEEEEEEEEGGSGASDSSEISSEEEDSSTESDSSSGSSQVSVQSIRFRRTSFCKPPSVQAQANFLYHLASAAAATKPAAFEDAGRLPDLKSSVKAESPEEWSLQSWAPKGTPVYCPASLGSCFPEIRNDRVSEITFPHSEISSTVKRTDLTINCHAEGASSPSPKTNNVFPQQRILREARKCLQATPTTHCAENSTIAARFLNNDSCGTTANSGKDSKIPHCPEFATDLPSLQSDPRVDTATAAAAAAAATKAESLCTGTGDKTLPFLHNIKIKVEDSSANEEYEPELITNKLKWECNDAEGEFYNMTEKKEEDALVPTAKEGFACPEKETPSLNPLAQSQGLSCTLGSPKPEDGEYKFGARVRKNYRTLVLGKRPVLQTPPVKPNLKSARSPRPTGKTETHEGTLDDFTVLNRRKKVASNVASAVKRPFNFMANFPCPPSLIIGKDGDLWPAYSLNTTKDSQPPHKAHPIWKWQLGGSAIPLPPSHKFRKFNS
What are the official names of this protein?
SKI/DACH domain-containing protein 1, Protein DLN-1.
What is the protein family that this protein belongs to?
Belongs to the DACH/dachshund family.
Protein: KDGD_LEPCP
Sequence: MSPQELKNVLQSGLLSFPLTDFDRELNFAPKPYAERLKWLQPYGASALFAAGGTGEFFSLEPGEYSDVIKVALDTCRGRTPIIAGAGGGTRVAIQYAQEAERLGAQGVLLLPHYLTEASQEGLIAHVQAVCRSVRFGVTVYNRGACKLTPASLLVLAETCPNLIGFKDGIGDIETFVSIRQTLGERFAYLGGLPTAEVFAGAYKAMGCPVYSSAVFNFIPKTAMEFYNAHAAGDSATCDRLIRDFFLPYIALRNKNHGYAVSIVKAGATLIGHGAGPVRPPLSDLKPAEVAELAALMAKLGPQ
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: SP65_DICDI
Sequence: MKVLLLLVCLVFAYVNASYDACYNVVCPSNYQCRAEGDQAYCVPEHHEYGCDRHSCGRGYECVERWDSFCCKPIHHRPHPHPRPPHPHPRPTNCDYTSCPREFDCHVINRNVTACLPDNHVCRDFQCPVGTHCFNGERGPHCVSDTHYPNLCRVTKCSYDFTCKMVRGNPTCLRNHDGISTHSPTHTPTHSPTTSPTHCPSCTELAPFCHSAGLVCRTILNPSCVSAVRGIINTRSCCTYIAVCASNSTSTTGATTGATTPTSTTGAATTAAATTTTATSTTGAATTAPATTTTTSTTGAATTAPATTTTSTTGAATTAPATTTTTATTIVGVTTANSVGGLTTTRATTVAGVTTANSVGGLTTAGITTVAGATTGNSVGGLTTARATTVADVTTANSVGGLTTAGVTTVAGATTGNSVGGLTTARATTVADVTTANSVGGLTTSRATTIAGATTANSIGGLTN
What is the function of this protein?
Forms a triad with cellulose and pspB that is essential for spore outer layer formation.
What are the official names of this protein?
Spore coat protein SP65, Spore coat protein E.
What are the subcellular locations of this protein?
Spore wall. Note=Depends on pspB for incorporation into the coat. Accumulates initially in vesicles distinct from prespore vesicles (PSVs).
Protein: DDX42_XENLA
Sequence: MNWNKGGSGNKRGFGFGGFAISTGKKEEPKLPQVSHSAFQSASSKYGSTSNQLPSFYKIGSKRANFDEENSYFDDEEEDSSNVDLPYIPAENSPTRQQLRSKTDSDSEEDPLEAFMAEVEDQAAKDMRKLEERDKEKANARGIRDDIEEEDDQEAYFRYMAENPTAGLVPEEEEDNLEYDSDGNPIAPTTKRIIDPLPPIDHTEIEYPPFEKNFYEEHEAITSQTPQQITELRHKLNLRVSGAAPPRLCSSFAHFGFDEQLLHQIRKSEYTQPTPIQCQGIPVALSGRDMIGIAKTGSGKTAAFIWPILVHIMDQKELQPADGPIAVIVCPTRELCQQIHSECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVTYLVFDEADRMFDMGFEYQVRSIANHVRPDRQTLLFSATFRKKIEKLARDILVDPIRVVQGDIGEANEDITQVVEILPSGPEKWTWLTRRLVEFTSTGSVLVFVTKKANAEELAANLRQDDHPLGLLHGDMDQSERNKVISDFKKKSIPVLVATDVAARGLDIPSIKTVVNYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTSKESNFAGDLVRNLEGANQYVSKELLDLAMQNSWFRKSRFKAGKGKKLNIGGGGLGYRERPGLGAESSEHGTGGNVMSNYEAFKPSGGAMGDRLSAMKSAFQSQYKNHFVAASASTQKTGTSSINSGAWTSAGSLSSVPSAHPPSGKLPAEAAPPPVHTAMLGFTSSGTLSSIPTGYPANISSASYPAATLFGARDGASAGTESGGRERHSDSKGRHGDSHRPSDREGYRHGDGHRHSSSSRHGERNGGEGRRESSRDGRRDSSRDGESRRDGSRDGGEGRRESSRDGEGRRESSRDGDGRRESSGDGRREVVGDDGDSRKEGTREAKTDTFAIPVPPKRKKSRWDS
What is the function of this protein?
ATP-dependent RNA helicase.  Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures.  Unwinding is promoted in the presence of single-strand binding proteins.  Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein.  ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands.
What are the official names of this protein?
ATP-dependent RNA helicase DDX42, DEAD box protein 42.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX42 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPD_MYCPN
Sequence: MINAQAFGMALFQLSEEEKKVKKVYDQSHDFLKLARNFKDGSLAALLNAYTLTKKEKLKLIDKLFKNHFCDLFVDFLKTIVLKGYFNLVEQALKYFFDCVENEKHVQFIRIITAFELSAPQLKRIVAAMEKKLNSKIVYKTEIDKSLISGIRIESSAQLFEKNIRDQLSRLMEQFKGN
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYE2_HELAH
Sequence: MSLIATRFAPSPTGYLHIGGLRTAIFNYLFARANQGKFFLRIEDTDLSRNSIEAANAIIEAFKWVGLEYDGEILYQSKRFEIYKECIQKLLNEDKAYYCYMSKDELDALREKQKVRKETPRYDNRYRDFKGTPPKGIEPVVRIKIPQNELICFNDGIKGEVRVNTNELDDFIIARSDGTPTYNFVVTIDDALMGITDVIRGDDHLSNTPKQIVLYKALNFKIPNFFHVPMILNEEGQKLSKRHGATNVMDYQEMGYLKEALINFLARLGWSYRDKEIFSMQELLELFDPKDLNSSPSCFSWHKLNWLNAHYLKTQSTQELLKLLKPFNFSDLSHLNPTQLDRLFDALKERSQTLKELALKIDEVLIAPIEYEEKVLKKLDQVLVTPLLEKFKLELNQADFNDENALENAIHKIIEEEKIKVGSFMQPLRLALLGKGGGIGLKEVLFILGKTESIKRIEKFLKN
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRP_LOTGI
Sequence: MLSLWAIGLLGLLNQVEALWSPSSYQSPAQQRSAQFSSSGWGTSPAAQNPWSFNRPMPNTNMPNMNTGSLPGSMPGAMPGSMPGAMPGSMPGAMPGSMPGSMPGSMPNAMPGAMPGGTGSGFMAGAMPGAMPNMRSSNNMMGNMRNGYPPSYMTPSPRNTICVAPVSQPRLCMVNGENTHKYRLKDVIEFLGHPNIEKVPKCVPGVPRVNCADYYAAQYIWKRGYCYCKNFHSNLPSYQMGSTQIRCVLNNCGACSQEFYVDKQRVVKCE
What are the official names of this protein?
Methionine-rich protein, Uncharacterized shell protein 19, LUSP-19.
What are the subcellular locations of this protein?
Secreted.
Protein: RNZ_SYNSC
Sequence: MQVTFLGTSSGVPTRARNVSAVALRLPQRSEMWLFDCGEGTQHQFLRSDLRLSQLRRVFITHMHGDHVFGLPGLLASLGLAGSSSAGVDLYGPDPLESYLNGVLRTSSTRIGYPLAVHRVRDAAEQGTLLFEDDDFTVRCTLLTHRVPAYAYRIEQKPLAGRFDIEKARELNIPPGPVYAQLKRGETVTLEDGRSIDGTSLCGEERPGVSVVYCTDTVFCEAAIELARGADLLIHESTFAHGEAEMAFQKQHSTSTMAAQTAAEAGVGQLVLTHLSPRYVLGNPVTPQDLLNEAKAIFPNTLLAKDFLSIDVKPRCNSS
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: CP2A4_MOUSE
Sequence: MLTSGLLLVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFVGNFLQLNTEQMYNSLMKISQRYGPVFTIYLGSRRIVVLCGQETVKEALVDQAEEFSGRGEQATFDWLFKGYGIAFSSGERAKQLRRFSITTLRDFGVGKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSLQFTATSMGQVYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEHNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKYPDIEAKVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQRFADLIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFHFKSTQEPQDIDVSPRLVGFVTIPPTYTMSFLSR
What is the function of this protein?
Highly active in the 15-alpha-hydroxylation of testosterone.  Also active in the 15-alpha-hydroxylation of progesterone and androstenedione.  Little or no activity on corticosterone, pregnenolone, dehydroepiandrosterone, estradiol or estriol.
What are the official names of this protein?
Cytochrome P450 2A4, CYPIIA4, Cytochrome P450-15-alpha, Cytochrome P450-IIA3.1, Testosterone 15-alpha-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: MY61F_DROME
Sequence: MASFNSQLKMETGLHERDRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFTEVEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEKELRSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLRAQVIIMQSYCRRKLAQQAAKKRREAADKIRAFIKGFITRNDAPNGFNEEFIANAKRMWLLRLAKELPTKVLDKSWPHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFELKVLAEKVFKGKKNNYASSVSTWFQEDRIPKEHIQRVNDFVASTFGSEQLKYQSFCTKFDRHGYKSRDRFILLSNKAIYVLDGKTYKQKHRLPLDKIDFTLTNHNDDLMVIRIPLDLKKDKGDLILIIPRIIEFSTYIIDTVGTASIVSIVDRNSLEHNVVKGKGGVIDIQTGAEPGVVRDKGHLVIIGTQ
What is the function of this protein?
Unconventional myosin that functions as actin-based motor protein with ATPase activity (PubMed:30467170).  Binds to membranes enriched in phosphatidylinositol 4-5-bisphosphate, and can glide along actin filaments when anchored to a lipid bilayer (PubMed:30467170).  Functions as antagonist for Myo31DF, an unconventional myosin with an essential role in the establishment of body left-right asymmetry (PubMed:16598258, PubMed:18521948, PubMed:22491943, PubMed:25659376, PubMed:30467170).
What are the official names of this protein?
Unconventional myosin IC, MyoIC, Brush border myosin IB, BBMIB, Myosin-IB, MIB, Unconventional myosin 1C, Myo1C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Protein shifts from the basolateral to apical domain in enterocytes and follicle cells (PubMed:7589814). Colocalizes with the actin cytoskeleton (PubMed:22491943, PubMed:25659376).
Protein: NDK_BDEBA
Sequence: MSIEQTFSIIKPNAMKKNAIGDIVSMFEANGLKIAAAKITVLTTAKAEEFYAEHKARPFFGELVSFMTSGPVMLMCLQGEGAVLKNREIMGATDPKKANPGTVRAKFGDNVGENAVHGSDSPESAARELALFFEKHEICNV
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V239_FOWPN
Sequence: MEEGKPRRSSAVLWMLIPCGSIIIVLSVFVIILSTRPPVPPDIKILYCKEGWVGYNKNCYFFSEEKNNKSLAVERCKDMDGHLTSISSKEEFKFILRYKGPGNHWIGIEKVDFNGTWKLEDGSSYDNIVPIKGIGDCAYLSDRSIMSSFCFLPKKWICRIILL
What are the official names of this protein?
Putative C-type lectin protein FPV239, BamHI-ORF8.
Protein: RS12_THIDA
Sequence: MPTINQLIRKPRQAPVEKSKVPALKACPQRRGVCTRVYTTTPKKPNSALRKVCKVKLTSGFEVISYIGGEGHNLQEHSVVLVRGGRVKDLPGVRYHTVRGSLDTAGVKDRKQSRSKYGAKRPKKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ABT1_HUMAN
Sequence: MEAEESEKAATEQEPLEGTEQTLDAEEEQEESEEAACGSKKRVVPGIVYLGHIPPRFRPLHVRNLLSAYGEVGRVFFQAEDRFVRRKKKAAAAAGGKKRSYTKDYTEGWVEFRDKRIAKRVAASLHNTPMGARRRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLQSVERGQRFLAADGDPARPDGSWTFAQRPTEQELRARKAARPGGRERARLATAQDKARSNKGLLARIFGAPPPSESMEGPSLVRDS
What is the function of this protein?
Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator.  Can act as a regulator of basal transcription for class II genes (By similarity).
What are the official names of this protein?
Activator of basal transcription 1, hABT1, Basal transcriptional activator.
What is the protein family that this protein belongs to?
Belongs to the ESF2/ABP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: TMM43_RAT
Sequence: MAANYSSTGSRKEHVKVTSDPQPGFLERLSETSGGMFVGLVTFLLSFYLIFTNEGRALKTANLLAEGLSLVVSPDSIHSVAPENEGRLVHIIGALRTSKLLSDPNYGVHLPAVKLRRHVEMYQWVETEESNEYTEDGQVKKETKYSYNTEWRSEIVSSKNFDREIGHKNPSAMAVESFTATAPFVQIGRFFLSAGLIDKIDNFKPLSLAKLEDPHVDIIRRGDFFYHSENPKYPEVGDVRVSFSYAGLSSDDPDLGPAHVVTVIARQRGDQLIPYSTKSGDTLLLLHHGDFSAEEVFRREQKSNSMKTWGLRAAGWMAMFMGLNLMTRILYTLVDWFPVFRDLVNIGLKAFAFCVATSLTLLTVAAGWLFYRPLWAALLGCLALVPIIIARTRVPTKKLE
What is the function of this protein?
May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane.  Required for retaining emerin at the inner nuclear membrane (By similarity).  Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26 (By similarity).  In addition, functions as a critical signaling component in mediating NF-kappa-B activation by acting downstream of EGFR and upstream of CARD10 (By similarity).  Contributes to passive conductance current in cochlear glia-like supporting cells, mediated by gap junctions and necessary for hearing (By similarity).
What are the official names of this protein?
Transmembrane protein 43, Protein LUMA.
What is the protein family that this protein belongs to?
Belongs to the TMEM43 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Nucleus inner membrane; Multi-pass membrane protein. Note=Retained in the inner nuclear membrane through interaction with EMD and A- and B-lamins. The N- and C-termini are oriented towards the nucleoplasm. The majority of the hydrophilic domain resides in the endoplasmic reticulum lumen (By similarity).
Protein: YCF37_GUITH
Sequence: MSFLLPFLYVSGLSLILLFILVFIISQIWSRRTADLRLVSIQEKIRNAKADGKDFYELGVIFLSKKLYDQAIINFRYALNLWELDDKTGLANLYNTIGFTYTQIAQYDLALFYYEKALLHEPNYLVTLKNIGFIYEKTNNLVKAKDIYLQILKYDVDNKFATDKLNLLTGRLIRDDRI
What are the official names of this protein?
Uncharacterized protein ycf37.
What is the protein family that this protein belongs to?
Belongs to the ycf37 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RRF_SULNB
Sequence: MVNEIFEHTKENMDKSLEALKRDFASLRTGKVTTNIVDNIKVDYYGTPTPLNQVGSVIATDATTISITPWEKNLLSDIERAIQEANIGVNPNNDGDFIKLFFPPMTSEQRQEIVKQAKAMAENARVAIRNIRKDANNKIKKLEKDKEISEDESKRAHDEIQKITDDHIGMVDELFKAKEADILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_FRAP2
Sequence: MRTDDFDYKLPEELIASYPLENRDASRLLKLNKQTGEILDHKFTDFIDFINPEDLLIFNNSKVMLARLYGEKITGAKLEYLIERVKTPKIFETHIKANRSPAIGSEIYVQDTLAKILEKDGGMYLLELQGNKDIYQLMEEFGHIPLPPYMKRDDEEFDAERYQTVYAKDLGSVAAPTAGLHFSEELMQQIKAKGTDIAYITLHVGSGTFKPVQVDDVNNHKMHSEVISVSEDVCEKIRQTKANGGRVIAIGTTSVRSLETAGQSGEIQPYQGETDIFLYPGKKFNIVDAMITNFHLPKSTLIMLVSAFADKEKIMKAYEHAIAEKYRFFSYGDAMFIF
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_BACMK
Sequence: MLRDLFVKKKKYAAIPSEQVRKDVPDGVMTKCPKCKKIMYTKELLKNLKVCVNCGYHHPMNAWERLDSILDEGSFREYDKEMVSLNPLEFPGYEEKLENDRKKTKLNEAVVTGEGTIDDMLVVVAVMDSRFRMGSMGSVVGEKIARAVEKAYDLQVPFIIFTASGGARMQEGILSLMQMAKTSVALKKHSNAGGLFISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRVIEQTVREKLPEDFQTAEFLLEHGQLDAVVHRDDMRESLRKILEVHQGGGMAVWQS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.