PharMolix/UniProtQA huggingface dataset:
Protein: HPRL3_HALTV
Sequence: MDPTLKQLARSLREAPVVDRDGYEYFVHGVTDGVPPLDPAVLEAIADGIRERIDLEGVDTLVAPEAMGIHHGTALSLATRIPLVVVRKRSYGFPEEVAVHQETSYGESDLYLNGVDAGDRVVVVDDVLSSGGTIEAVCEALEAVGAEIVDIVTVLRRVDADHGDISRPVTSLLDVRVRDGALEVVE
What is the function of this protein?
May catalyze a purine salvage reaction, the substrate is unknown.
What are the official names of this protein?
HGPRTase-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
Protein: LDH1_BIFLO
Sequence: MVTMNRNKVVIVGTGQVGATAAFGIVTHGLCNELVLIDCSAAKALGEARDLDDGSEFQDRHVKVRAGDYADCKDADIVVITVGRKPPANSNRMAELGFTVGLVGEVVDNVMASGFDGVIVMVSNPVDVMAWYAWKRSGLPRTQVLGTGTALDTSRLKTIIGEETGLDPRNVGGFVMGEHGDSQFTAWSTVSLGGKPFARFLADNQDRFASVSTTEIEEKTRTRGNEIVAAKGGTNFGIASTVAGIVQTILWDERRIVPVSTLLDGEYGEHDVFLGVPTELRANGANEIVELDLSEDERAKLHHSAELVREHCEGLL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1639_DICDI
Sequence: METINNRNPQEINTNETMIENPKDKVSNNNFIPKLNLNNNNLNKINQPGDSETLDNRSNPSSPIESPLSTARISSSHNILFKTRGYYFIKPISKGGYGQVFLAITKSNKFFAIKSINKRDTIGKHMVKELMVERNILVQYQNQSIVKLFECFQTKKKLYMVMEFLHGGDCASLLHSLNTLEEREAKNIIAQIVNGLEFIHSCGIIHRDLKVENLIFDKNGIIKIVDFGFSEVGFTGNSIKNGNKKNNKCLGTPYYMSPEVINKRGYGKTIDWWALGIIIFELLSGETPFVGDNQNMIFEKITNYTNEINFPSYFSEVAIDLIQKLLQVDPLKRLGANGADEVKRHPFFNGVNWSKIYSPESLTFKPKIENEYDSSYFFERENVKKTVSAKKTNNKKPIKRYLFKGFNFKKN
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0280717.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Protein: DIA1_YEAST
Sequence: MGSISRYLLKKAADGLKDEQRLKIEMSDSKSVPECFHFNRERRMPIAEINGEDGFFMFPSQQSLENFENTKKYSNELSPDAIGIPLFQIINCTLPFGKRGHSNTVVGNVPYYKIFKFILRTADEPPPYTVAKIVCSNNGLILYKVPLYDIYKNVSQANVTYSFVGTTSTEPNLLAMAHREGHRDLDTKVNNLNLRWHVTYSPVVTNDHYKLILLADYEVNRLDEDVIRAAKNKMSIDQKDQKVQRFVAAHYTREFETSLFRWVAQEGHLILGEYSTDQGSFGLNNIPPLTEELGCQSLLIHYIEYMKRQRKKIAKEARRQNKRNVANTTNMNMNLM
What is the function of this protein?
Involved in regulation of invasive growth.
What are the official names of this protein?
Protein DIA1, Digs into agar protein 1.
Protein: ZPR4_ARATH
Sequence: MERLNSKLYLQNCYIIKENERLRKKAQILNQENQQLLFELKQKLSKTKNSSGSNQGNNNNNNNLSSSSSASG
What is the function of this protein?
Competitive inhibitor of the HD-ZIPIII transcription factors in shoot apical meristem (SAM) development (Probable).  Acts by forming non-functional heterodimers (Probable).  Part of a negative feedback loop (Probable).  Essential for proper functioning of stem cells in the SAM (PubMed:18408069).
What are the official names of this protein?
Protein LITTLE ZIPPER 4.
Protein: VATB_PYRAR
Sequence: MLTPVVSYSTVREVKGPLIVIEKTRGVSYGEIGEVVGPDGEPRRVQVIEVGTDYAVAQVLGGTLGLPARGSTVRFYGKTLKIPVSEQLIGRILDGKGQPRDHMPLPPPEDFRDVNGEPLNPYSREYPEEPIETGISAIDGLYTLVRGQKLPIFSGTGLPHNLMAAQVVRQSTVRGSEEGFAVVFVGVGIKTEEALFFMDEFRKTGALRRAVAVLNLASDPVAERVLAPRVGLTIAEYLAWQLGYHVLVVITDMTNYCEGLRELSSGRGELPGRRGYPGYMYTDLATIYERAGKAHGRKGSVTQFPILTMPHDDITHPIPDLTGYITEGQLVLSRAMWGKGIYPPFDVIMSLSRLAKDAIGEGKTREDHKDVANTLIAAYSKALEIRNLATLVGERNLGWRERRYLRFADAFEQKFIKQGYYERRSFEETLDIGWDVLSILPEDELTNARPQITQKFYRRHVYESVQL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: FABH_STAEQ
Sequence: MNVGIKGFGAYAPKNIIDNAYFEQFLETSDEWISKMTGIKERHWADEDQDTSDLAYNASIKAIEDAGIQPVDIDMIIVATATGDMPFPSVANILQERLGTGKVATMDQLAACSGFMYSMITAKQYIQSGDYKHILVVGADKLSKITDMTDRSTAVLFGDGAGAVVMGEVAEGRGIISYEMGSDGSGGKYLYLDRETGKLKMNGREVFKFAVRIMGDASTRVVEKAGLSSEDIDLFVPHQANIRIMESARERLGIEREKMSVSVNKYGNTSAASIPLSINQELQNGKIKDDDTLVLVGFGGGLTWGAIVIKWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_RHILO
Sequence: MTRQFVFSSESVGAGHPDKMADNISDAILDAILRTDPKARVACETLVKTGMVVLAGEITSHAVIDYTQVARDTILDIGYDDDGIGFDGRRCAVVLALTEQSPDISQGVDEGRGQDLEQGAGDQGLMFGFACNETDTLMPLPIQLAHHLTKRQAEVRKTGQLGWLRPDVKSQVSVRYEGLRPVALDTIVLSTQHDEAVSQATVREGVIEEIIKPVLPTHLDTTGIRFLVNPTGRFVVGGPAGDCGLTGRKIIVDSYGGTGRHGGGAFSGKDPSKVDRSAAYAARYVAKNIVASGLAEVCEVQLAYAIGVASPVSVMVNTFGTARIEEKRIECLVLELFDLRPKGIIKMLDLVRPIYRNTATYGHFGREEPEFTWEKTDRADDLLREAGPAAA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGT1_BOVIN
Sequence: MAAAAAGPVAAASRLFRSFSDALIEQDPQAALEELTKALEQKPDDAPYYCQRAYCHILLGNYSDAVADAKKSLELNPNSSTALLRKGICEYHEKNYAAALETFTEGQKLNSADADLTAWIKRCQEAQNGSQPEVSASQRTHQSKIKYDWYQTESQVIITLMIKNVQKNDVNVEFSEKELSALVKLPSGDDYSLKLRLLHPIIPEQSTFKVLSTKIEIKMKKPEAVRWEKLEGQGDVPNPKPFIADVKNLYPSSSHYTRNWDKLVGEIKEEEKNEKLEGDAALNKLFQQIYSDGSDEVKRAMNKSFMESGGTVLSTNWSDVGKRKVEINPPDDMEWKKY
What is the function of this protein?
May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Protein SGT1 homolog, Suppressor of G2 allele of SKP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SGT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus upon heat shock, requiring S100A6.
Protein: AUG2_ARATH
Sequence: MSMGGDTTWVGKKPIRRIGGLSDALSIASDLGFAVAPPPSQEELQSFASSNGERGDDLIRVLRELSVVQRKIADLQVELQGRKDDKNVAHLTHVGEMQKKIETLSRITQILKDVIQNKDRIIARLQQPYSLDCIPVEAEYQKQFSELLMKAASDYGALTASVSDFQWSQNFKEPPSVWGEMLRPIPVALASCTRFFEAMSAMRESFATLQELRVGNSAVSLPTTPGGNEMTHRDSDCVTPPQGRIESSFDDLAVHKTRRQNNDQNEEEEEEEEEEDGNNNGNRRLSWPPSVKKSSV
What is the function of this protein?
Contributes to the assembly of the acentrosomal spindle and phragmoplast microtubule arrays as part of the augmin complex.
What are the official names of this protein?
AUGMIN subunit 2.
What is the protein family that this protein belongs to?
Belongs to the HAUS2 family.
Protein: ABEC2_BOVIN
Sequence: MAQKEEAAAAAEPASQNGEEVENLEDPEKLKELIELPPFEIVTGERLPAHYFKFQFRNVEYSSGRNKTFLCYVVEAQSKGGQVQASRGYLEDEHATNHAEEAFFNSIMPTFDPALRYMVTWYVSSSPCAACADRIVKTLNKTKNLRLLILVGRLFMWEEPEIQAALRKLKEAGCRLRIMKPQDFEYIWQNFVEQEEGESKAFEPWEDIQENFLYYEEKLADILK
What is the function of this protein?
Probable C to U editing enzyme whose physiological substrate is not yet known.  Does not display detectable apoB mRNA editing.  Has a low intrinsic cytidine deaminase activity.  May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
What are the official names of this protein?
Probable C->U-editing enzyme APOBEC-2, mRNA(cytosine(6666)) deaminase 2.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: DNAK_MYCMM
Sequence: MARAVGIDLGTTNSVVAVLEGGDPVVVANSEGSRTTPSVVAFARNGEVLVGQPAKNQAVTNVDRTIRSVKRHMGGDWSIEIDDKKYTAPEISARVLMKLKRDAEAYLGEDIADAVITVPAYFNDAQRQATKDAGQIAGLNVLRIVNEPTAAALAYGLDKGEKEQTILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDDRVVEWLVDKFKGTSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLTRAEFQRITQDLLDRTRKPFQSVIADTGISVSDIDHVVLVGGSTRMPAVTELVKELTGGKEPNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGVMTKLIERNTTIPTKRSETFTTADDNQPSVQIQVYQGEREIAAHNKLLGSFELTGIPPAPRGVPQIEVTFDIDANGIVHVTAKDKGTGKENTIRIQEGSGLSKDEIDRMIKDAEAHAAEDHKRREEADVRNQAETLVYQTEKFVKEQREAEGGSKVPEDTLNKVDAAVAEAKSALAGTDIAAIKSAMEKLGEESQALGQAIYEATQADAAAAGAPGGQPGGAEPGADDVVDAEVVDDDQESK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GLMS_ALKCK
Sequence: MCGIVGYIGNEDAKEILLSGLEKLEYRGYDSAGIAVRTESDTEVFKEKGRIATLRKAVDENVHSTVGIGHTRWATHGVPSQLNAHPHQSATERYTLVHNGVIENYEQIKRDYLADVQLKSDTDTEVIVQFIEQLAGEGLTTEEAVSKALSLMKGSYAIALLDKDDPDTIFVGKNKSPLLVGVGENANVVASDAMAMLTVTDQFIEIMDEELVIVRRDRIEIKTLAGDVQERKPYTAELDVSDIEKGTYAHFMLKEIDEQPFVIRNIIQKYQHEDGSTRLDEDIRAAMKDSDRIYIVAAGTSYHAGLVGKQLLERVSGKPTEVHIASEFLYNMPLLSEKPLFVFISQSGETADSRGVLVNVKKQGHRTLTITNVPGSTLSREADYTLHTFAGPEIAVASTKAYTAQIAVLALLAVDVANAAGKTLDFDLLQELAIAANAMESLCNQKDEMEQIARDYLSVTRNAFFIGRTADYFVALEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVIALATQEHVNLSIRGNVQEVASRGAATAIISMEGLDQEGDAVVLPRVHELLTPLVSVIPTQLIAYYAALHRGCDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTG34_ARATH
Sequence: MAVAVTAVLFLAVVIAPQWTETKKPPRPSDTSDTSGTSGRDRRTMCPLSIPGIVQNCYATLNAFPSKECCKDLKTASKREVTCLCNNVIAHPDPLYTNTNQVNKACGVLDKYACDAGNSNGGATKKIVASMGLFGVVASLFF
What is the function of this protein?
Probable lipid transfer protein.
What are the official names of this protein?
Non-specific lipid transfer protein GPI-anchored 34, AtLTPG-34, Protein LTP-GPI-ANCHORED 34.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: XYNB_PRUPE
Sequence: ADAIKAGLDLDCGPFLAIHTEAAVRRGLVSQLEINWALANTMTVQMRLGMFDGEPSAHQYGNLGPRDVCTPAHQQLALEAARQGIVLLENRGRSLPLSTRRHRTVAVIGPNSDVTVTMIGNYAGVACGYTTPLQGIGRYTRTIHQAGCTDVHCNGNQLFGAAEAAARQADATVLVMGLDQSIEAEFVDRAGLLLPGHQQELVSRVARASRGPTILVLMSGGPIDVTFAKNDPRISAIIWVGYPGQAGGTAIANVLFGTANPGGKLPMTWYPQNYVTHLPMTDMAMRADPARGYPGRTYRFYIGPVVFPFGLGLSYTTFAHNLAHGPTLVSVPLTSLKATANSTMLSKTVRVSHPDCNALSPLDVHVDVKNTGSMDGTHTLLVFTSPPDGKWASSKQLMGFHKIHIATGSEKRVRIAVHVCKHLSVVDRFGIRRIPLGEHKLQIGDLSHHVSLQTNLGEIKV
What is the function of this protein?
May be involved in cell wall metabolism, related to senescence.
What are the official names of this protein?
Putative beta-D-xylosidase, PpAz152.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
Protein: ANXD6_ARATH
Sequence: MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA
What are the official names of this protein?
Annexin D6, AnnAt6.
What is the protein family that this protein belongs to?
Belongs to the annexin (TC 1.A.31.1) family.
Protein: NXF2_CAEEL
Sequence: MRGQNRRGYRNIEGRLSLSSHSSHSSPRQTHVTNLRPAEIKVVQDVVDGCYVATDDVLNLSNFSKNTEFVERDMLMCLTKTRVMSVVLQHIGYKYPRISGISFSNNRLCHLDHLSSLSSISKFLKFLDLSHNQISSGEELKKLGTIPVETVFFEGNPVCEKFVQCAEYANFIQKTFPKCSNLDGMEVEPKPDHNRIEQIIPFRNGYYGSDEVRTLVEEFIITYYKIYDGADGQQTRKQLLDAYDTNNSTFTHTVVCLWDPIKFVMYPDSESYRMYLRTSHNVLNQEYFAANRASRISHGAMDIVVALSRLPATIHLMDTFVVDVFLVSATLLGFTLHGTFRDGPSAIKPENTEEHDNYFTRTFMVAPRGEGKVAIVSDQLFISSMSKRRGDQYRMLVETATDIDQ
What is the function of this protein?
Involved in the export of cellular mRNA to the cytoplasm (PubMed:23149939).  Plays a role in the nuclear retention of unspliced mRNAs (PubMed:23149939).
What are the official names of this protein?
Nuclear RNA export factor 2.
What is the protein family that this protein belongs to?
Belongs to the NXF family.
What are the subcellular locations of this protein?
Nucleus. Note=Not localized at the nuclear rim.
Protein: WNK6_ORYSJ
Sequence: MMPPKPAAEDVADEQPEPPDEDPDVAEADPTGRYLRYREIIGSGSSKTVYKAFDAVDGIEVAWGKVEINERIMGSSKELQRLRTEIQLLKSLQHKHILKLYASWVDTNRRTVNIVTELFTSGNLREYRTKHKKVDMKAMRRWAKQILTGLEYLHSQKPPIIHRDLKCDNIFINGNHGKVKIGDFGLAMVMQQRKTRSIQGTIEFMAPELFGENYNELVDIYSFGMCMLEMVTCECPYSECKGFIQIYKKITEGVKPAALSKVKDAEVRGFIESCLASVSDRLPASELLKSPFLQSDDANHRSSNSVQEPVKFPENNFTKDEPIFVSLAPNNGTVNGKEQSFILVLQKSDFLLEGNMSTTNPVMLFLRFPGPDGKFKNVQFPFDMEKDTSLSVSTEMVEQLELPEWNNPVLAELIDAFLLHILPSWKPCVKVGKMLPSSS
What are the official names of this protein?
Probable serine/threonine-protein kinase WNK6, OsWNK6, Protein kinase with no lysine 6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily.
Protein: MUTS_PSEA6
Sequence: MPKTNSSAASTNANPSSLQQHTPMMQQYLKIKAEHPDILLFYRMGDFYELFFDDAKKAAELLDISLTARGKSGGNAIPMAGVPYHAVENYLARLVKMGQSVAIVEQVGDPATSKGPVERKVQRIVTPGTVSDEALLNDKQDSILAAVFCPTQKANQELIFGYATLDVTSGRFTLCELSGEEALAAELQRTNPVELLYPDDFAYSHLINQRKGLRRRPQWEFDLQTATNQLTSQFGTNELSGFGVQNHQVGICAAGCVMQYIKDTQRSALPHIDRIVLESHNDTVVMDAATRRNLELTFNLSGGIENTLASILDKTSTPMGSRLLQRWIHRPLTDVTVLKKRQRNIQGLMESPYTQLQSALKKIGDMQRVLARLALRSARPRDFARLRQAFALLPDIQHYLEHEISHTSESAQPSDLLHLAEKISQYPDFADLLERAVIEAPPVLIRDGGVIKEGYNEELDRLRELSKGATDYLEELELREKERTGIASLKVGYNRVHGYFIEVSRSQSDLVPVEYVRRQTLKNNERYIIPELKEHEDNVLSSQSRSLALEKRLYDELFDLLLPQLTQLMQSADALAELDVLTNLAERAESLDYHRPELCPQSGIHFSQGRHPVVEQVSDAPFIANPINVNPDRRMLVITGPNMGGKSTYMRQTALIVLMAYIGSYIPAQDAQIGPIDRIFTRIGASDDLASGRSTFMVEMTETANILNNATANSLVLMDEIGRGTSTYDGLSLAWACAEYLATKLQSFTLFATHYFELTGLADALPELANVHLDAVEHGESIRFMHAVQDGAANKSYGLQVAQLAGVPKLVVQAAKRKLHELETGDISKQGRQETSPVNTVYATEKVETQLDLLSQTSEAEDLLHSIQPDDLTPKQALDYLYQLKKLVR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: TDH_FRATN
Sequence: MKALAKLKKQPGIWMIDDAPIPEYGYNDVLIKIKKTAICGTDLHIYNWDKWSQNTIPVPMITGHEFAGEVVAKGDGVTSVDIGDRVSGEGHLVCGQCRNCRAGKRHLCRKTIGIGVNVQGAFAEYLVMPAVNVFKIPDSISDDIASTFDPMGNAIHTALSFNLTGEDVLITGAGPIGLMAVKIARFCGARRIVITDINEYRLQMARDFGATVALNVAPFKNQDELVKQMRKVMSDIGMTEGFDIGLEMSGINSAISMMLDVMNHGGKLSLLGISAGDISVDWGAILFKGLTLKGIYGREMFETWYLMTSMLQAGMDMNPIITHRLHIDEFQKGFEIMKSGQCGKVILDWSS
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_RHORT
Sequence: MSSVLVRFAPSPTGRLHLGNARVAVLNWLFAHAHGGAMVLRLDDTDIARGTAEFAQAIRDDLLWLGLTWTREESQLARAARHAEAVDQLKAAGRLYACYETPEELEYRRRRQRAQGLPPIYDRAGLALSAAERAALEAEGRKPHWRFRLDHEETSWLDLARGPCHAHGGHLSDPVLVREDGSLLYTLPSVVDDIDFAISHVIRGEDHVVNTAVQIQICRALGAEPPHYAHLPLVLTAEGGGLSKRDNALSLGDLRAQGIEPAAINALLAALGTAEAPDPLKSLDELAQGFRLDAFGRAAPRLDPADLVRLSARIYHALSPSEARARGIAVSDALWLALRANLTTLSDLDELLPVVEGEITPLIAEEDRAMIDEAARLLPETPWDATTWATWTAAVKTATGRKGKGLFMPLRRALTGVDHGPELAALLPLIGRDKALARLRGEKA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_SYNR3
Sequence: MALQPASGARDLLPRDVGVNRWIAEQLAAVYQRWGYEEVTPPSLERIDTLEAGGAIQSHQVVQVVADEALGLRPEMTASIARAACTRLAAMQRPLRLHYRGSTFQAQRAEDQGLRIVEDLQSGVELMGAKGLAGDAELLRLLLDAGSHLPLSAEHQPTLLIGHQRLLSVLLEAVEPSLRSTVRRHVCGLNRVALSQLELPGQQRLQLLQLLQLRGEPAAVLNGLEALLGATDLLAELKQLISIIEEQASRAGIRLQLDPTFHPDFELYDGVMVKLVCQGLDAPVAIASGGRYDALVQRFSPVGAVASGVGFSFAVEAVRQLLEQADQLPPRLDGQLVLVAYSQSSQLHPALNLLEQLHQSGQPAELWPEPCANQDEAQGIATQRGVQTVRWVG
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E135_ARATH
Sequence: MLFKGVFAVFFVITLLYASLLIEVEGIGVNWGSQARHPLPPATVVRLLRENGIQKVKLFEADSAILKALSRTGIQVMVGIPNDLLAPLAGSVAAAERWVSQNVSAHVSSNGVDIRYVAVGNEPFLKAFNGTFEGITLPALQNIQSAIIKAGLATQVKVTVPLNADVYQSASNLPSDGDFRPEIRDLMLNIVKFLSDNGAPFTINIYPFISLYNDPNFPVEFAFFDGTGTPINDNGRIYDNVLDANYDTLVWSLQKNGFGNLTIIVGEVGWPTDGDKNANLMYARRYNQGFMNRQKANKGTPMRPGAMDAYLFGLIDEDAKSIQPGNFERHWGIFYIDGQPKYQLSLGSGNGLIPAKDVHYLAKKWCILAPNANLQDPQLGPSVSYACDHADCTSLGYGSSCGNLNLAQNVSYAFNSYYQVSNQLDSACKFPGLSIVSTRDPSVGSCKFKIMIKSEDASEASAMMPITRSTAVLLLLSICLYIVL
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase 5, (1->3)-beta-glucan endohydrolase 5, (1->3)-beta-glucanase 5, Beta-1,3-endoglucanase 5, Beta-1,3-glucanase 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: SSRP_CHLAB
Sequence: MASKEIVSNRKALHNYEVLESLEAGIVLTGTEIKSLRDHGGNLGDAYVAISKGEAWLLNASIAPYRFGNIYNHEERRKRKLLLHRYEIHKLEVKVAQKGVTIIPLGMFLSRGYVKVRLGCCRGKKSHDKRQTIIAREKEREIASAMKRYR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: LRC63_HUMAN
Sequence: MQKPPLLLRRPLPPKFTKLSLHEKKTHTAKTGKIESLHVAFTEDETTSIKMDRTRFPDVLRNQSLTPINIQNIFLDHCVQERVTAISSPQKSTKHVREQIPDTATGSIFFPHCNSASTRIFGKQTNKMESSRKFKTMKDVYTEKRLENILILSSKFSKPKSTPGSVIAQKLEKMHPKHQPLPESPGYTYQHISRDLSATVPSPPPMTVSMKPEGQWPEHFKSTATLTLRVTEFPGFVSLPTPVLPRKPHRQSVIETLVTENGNIESVPKQIPPRPPEGLTKTEKIESEIHVVRGEGFKTVAATRYETITAMTNLAIVNCQVYGRNALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKLNLTKIQFENNFTHPCFWRDNYLNNPQQLTQIISLFIVQNKLHKFYDKIPVEVQKLLKWGAQFLTELAPLSIYSSRKAITEGYIAVELPKFEESKNITEGLLTQKRYEEVMVKCINATTVTS
What are the official names of this protein?
Leucine-rich repeat-containing protein 63.
Protein: PXPA_OCEIH
Sequence: MQYQVDLNSDIGESYGAYTIGQDDEVMEFITSANIACGYHAGDHNIIHRTIDLAIKNNVAIGAHPGLQDLIGFGRRPMQISPEEVYQLTVYQIGAVQAFAQVKGHNLYHVKPHGALYNMAAKDTAIAKAIAQAVYDYNPNLILFGLANSELIRMGKEVGLNVANEVFADRTYQPDGSLTPRTSPNAMIHDTDEAVERVIRMVKENKIEAVDGTDISIIADTICIHGDGPKSLEFSRRLSHELKNQGISIQKREMHHG
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: SYH1_BACCZ
Sequence: MEMKNVKGTKDYLPEEQVLRNKIKRACEDTFERYGCKSLETPTLNMYELMSYKYGGGDEILKEIYTLRDQGKRELALRYDLTIPFAKVVAMNPNIRLPFKRYEIGKVFRDGPIKQGRFREFIQCDVDIVGVESVMAEAELMSMAFELFRTLNLEVTIQYNNRKLLNGILESINIPTERTSDVILSLDKIEKIGIDGVRKDVLERGISEEMADTICNTVLSCLKLSIDDFKDAFNTPLVAEGVNELQQLQQYLIALGINENAIFNPFLARGLTMYTGTVYEIFLKDGSITSSIGSGGRYDNIIGAFRGDNMNYPTVGISFGLDVIYTALSQKETISSTADIFIIPIGTELQCLQIAQQLRSTTSLKVELELTGRKLKRALNYANKENIPYVLIIGEEELSTETAMLRNMKEGSEVKVPLSSLSNYL
What are the official names of this protein?
Histidine--tRNA ligase 1, Histidyl-tRNA synthetase 1, HisRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_SERP5
Sequence: MAMTYHLDVVSAEKHMFSGLVQKIQVTGSEGELGIFPGHAPLLTAIKPGMVRIVKQHGEEEFIYLSGGILEVQPSVVTVLADTAIRGTDLDEARALEAKRKAEEHISSSHGDVDYAQASAELAKAIAKLRVIELTRRSM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNH_HERAR
Sequence: MEKIDIFTDGACKGNPGRGGWGALLVMGEREKELFGGEPGTTNNRMELKAVIEALNALTRPCEVIVHTDSQYVQKGISEWIHGWKARGWKTAARAPVKNVDLWQALDAAQARHQIEWRWVRGHNGHVGNERADALANRGVETVNSN
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_RICAE
Sequence: MKQNPKISLIGSGNIGGTLAHLISLRELGDIVLFDVTEGVPQGKALDLMQAGTIAGSDINIKGTNDYKDIEGSDAIIITAGLPRKPGMSREDLISINTGIMKTVAANVKKYAPDAFVIVITNPLDVMVYVMLKESGLPHNKVIGMAGVLDSSRFNLFLAEEFKVSVSNVNSMVLGGHGDAMVPLARYSTISGVPIPDLIKMGLSSNENIEKIIDRTRNGGGEIVALLKTGSAYYAPAASAIEMLESYLKDKRQILTCAAHLQGEYGVHDLYVGVPIMIGKEGVLRVIELQLTTEEKALFDKSVEGVKKLIETIK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.