PharMolix/UniProtQA huggingface dataset:
Protein: Y4520_BACC7
Sequence: MDGFDKTMKFSIQDEKQSVHVNDVLLTVYDALQEKGYNPINQIVGYLLSGDPAYIPRHKDARSIIRKLERDELIEELVKSYLKHHREE
What are the official names of this protein?
UPF0297 protein BCAH187_A4520.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: NUOC_RHIEC
Sequence: MSEALTELASYLGEARGNLIAASQLKYGELTLTATGENLIALLTFLRDDAKCGFVNMIDICGVDWPQRELRFDVVYHLLSPKKNLRIRVKVATDEDTPVPSACAVYPGADWFERETWDMYGVLFTGHPDLRRILTDYGFEGHPLRKDFPTTGFVEVRYDDAAKRVVYEPVELKQEFRNFDFMSPWEGTEYVLPGDEKAKQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LAMB_ECOL5
Sequence: MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQKNDWEATDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVGFGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDYGRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSGVAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVGIRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFATYAKWDEKWGYDYTGSSSTNPYYGKAVSADFNGGSFGRGDSDEWTFGAQMEIWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RS8_GEOKA
Sequence: MVMTDPIADMLTRIRNANMVRHEKLEVPASKIKREIAEILKREGFIRDYEYIEDNKQGILRIFLKYGPNNERVITGLKRISKPGLRVYVKAHEVPRVLNGLGIAILSTSQGILTDKEARQKGTGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: Y3950_MYCS2
Sequence: MVQSATEYGILVGVDSSAESDAAVRWAAREASLHDAPITLMHVIAPVVVSWPAGPYMATVLECQEENARHAIEQAQKVVADCLGETHGLTVQTEIRKESVARTLIDASKSAQMVVVGNRGMGALGRVLLGSTSTSLLHYASGPVVVVHGDDQAAHDSRLPVLLGIDGSPASEVATSHAFDEASRRGVDLVALHVWIDVGDIPPIGPTWEEQEETGRALLAERLAGWQERYPDVKVHRRVERAQPAYWLLEEAKQAQLVVVGSHGRGGFTGMLLGSVSSRVAQSATTPVMVVRPR
What are the official names of this protein?
Universal stress protein MSMEG_3950/MSMEI_3859, USP MSMEG_3950.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
Protein: AROD3_PETHY
Sequence: MQSLTPSSSGINIKLLNRKKIQTHRVTPSRVVIKCVYRFDSVNAGAAAVNTGVVNTPASNNTAGHVGASRTDWQSSCAILASKVVSQQQDTEKSGGAGNITAVNGHKILNLDLLPVESNRAKPLTITDLSPAPMHGAQLRVAYQGVPGAYSEAAAGKAYPKCEAIPCDQFEVAFQAVELWIADRAVLPIENSLGGSIHRNYDLLLRHRLHIVGEVQLPVHHCLLALPGVRKEYLTRVISHPQALAQCELTLTKLGLNVAREAVDDTAGAAEYIAANNLRDTAAIASSRAAELYGLDILEQGIQDDLSNVTRFVMLAREPIIPRTDRPFKTSIVFAHDKGTSVLFKVLSAFAFRNISLTKIESRPHRNRPIRLVDDANVGTAKHFEYMFYVDFEASMADVRAQNALAEVQEFTSFLRVLGSYPMDMTPWSPSRDA
What is the function of this protein?
Converts the prephenate and L-arogenate produced from the shikimate-chorismate pathway into 3-phenylpyruvate and phenylalanine (Phe), respectively (PubMed:20215586).  Involved in floral volatile benzenoids and phenylpropanoids (FVBP) production (By similarity).
What are the official names of this protein?
Arogenate dehydratase 3, PhADT3, Prephenate dehydratase ADT3.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: GDL_DROME
Sequence: MADIPATSEGSANTSEAVVEYQQPTPEFLQRKIYFLVDQLRTYHSELPENLQTRISYDLLTELANCVLNDGIFVIVKALMELQHETERHLIKIRMQAENEYEIEVAEWRSKIKDPEELRHILGLMKIKHTKKLHESDTKIIEILDQKVNDQQSTLQKAGVPGFYVTENPKEIKIQMFLLDFILRLSRLKYEPGK
What are the official names of this protein?
Gonadal protein gdl.
What is the protein family that this protein belongs to?
Belongs to the gonadal family.
Protein: TNF15_MOUSE
Sequence: MAEELGLGFGEGVPVEVLPEGCRHRPEARAGLAARSKACLALTCCLLSFPILAGLSTLLMAGQLRVPGKDCMLRAITEERSEPSPQQVYSPPRGKPRAHLTIKKQTPAPHLKNQLSALHWEHDLGMAFTKNGMKYINKSLVIPESGDYFIYSQITFRGTTSVCGDISRGRRPNKPDSITVVITKVADSYPEPARLLTGSKSVCEISNNWFQSLYLGAMFSLEEGDRLMVNVSDISLVDYTKEDKTFFGAFLL
What is the function of this protein?
Receptor for TNFRSF25 and TNFRSF6B.  Mediates activation of NF-kappa-B.  Inhibits vascular endothelial growth and angiogenesis (in vitro).  Promotes activation of caspases and apoptosis (By similarity).  Promotes splenocyte alloactivation.
What are the official names of this protein?
Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1, Vascular endothelial cell growth inhibitor.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: GIG5_ANEVI
Sequence: SKEGMSYEEPENDEGVACTGQYAESFCLNGGTCRYIQSIGEYYCICVGDYTGHRCEKKQV
What is the function of this protein?
Has both toxic and EGF activity.  Its EGF activity consists of rounding cells (morphological change) and inducing tyrosine phosphorylation of the EGFR in A431 cells, but with a lower potency that human EGF.
What are the official names of this protein?
U-actitoxin-Avd12b, U-AITX-Avd12b, Gigantoxin-5, Gigt 5.
What is the protein family that this protein belongs to?
Belongs to the EGF domain peptide family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: CRTN_STAA3
Sequence: MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDLAELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAKLKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIKGGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTADFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDDFRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSDEALTQQIKEIIYRKLATIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLAQSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIERGV
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes three successive dehydrogenation reactions that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene as intermediates, and 4,4'-diaponeurosporene (the major deep-yellow pigment in staphylococci strains) as the end product.
What are the official names of this protein?
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming), Dehydrosqualene desaturase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtN subfamily.
Protein: MHPB_SHISS
Sequence: MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPELVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSGIDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGRFTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVISAAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWVAAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase, 3-carboxyethylcatechol 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: YJJB_ECOLC
Sequence: MGVIEFLFALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAIGHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPB4_ASPTN
Sequence: MAPKPPAGTSSRAWEAVSPSLSEWVLDAVASWGFSKMTPVQASAIPLFMAHKDVVVEAVTGSGKTLSFLVPVVEKLLRLEEPIKKHHIGAIIISPTRELASQIHQVLLSLLAFHPPSAAAIKPPGEDDAPREKFSASTLKVVPQLLLGGSTTPAEDLSYFLKHSPNVLISTPGRLLELLSSPHVHCPQSSFEMLVLDEADRLLDLGFKETLQNILRRLPKQRRTGLFSASISEAVDQIVRVGLRNPVKVLVKVKGTSGVQDKRTPASLQMTYLTTPPAHKFLTLRPILTSLQPTPQKTIFFVSTCSGVDYLAAILPLLLGDDFQLIPLHGKHPANVRQKNFNRFINAHTPSILLTTDVASRGLDIPSVDLVVQIDPPSDPKTFIHRCGRAGRAGRRGVSVVLLHPGREEDYVSFLEVRKTPVTPFPHPISISDSDASTATEAARKIIKQDRALHDRGQKAFVSWLRSYSKHQASSIFRVADLDWEALGHAWGLLKLPKMPELRNFTGDRTLGVDLDWENYAYKDKQREKRRKEVLQESAEAGAQQTSNKRRASESVAWSNKVDQKNKKQKRREQKHLQQEKRRWEKMTEEEKQKARETQKMLEEIRQKNEEARALRRAEKAAGKAADNDGDDDEFEGFD
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase spb4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LOLB_SHEFN
Sequence: MRLSASLFHIALVTVLLVLAGCSVTPSEDFSPINVTNAAQAKAWELQGKIAVKTSEDKFSTNLYWLHQTKANDLRLTTVLGTTVLTLKTNQGMATLDVDGKTYRDSNAQDLLTGISGWSIPLDSLPLWITGQIGSNDKIVSYNPDGTIKQLISHDPEANWVVSFLGWQQQSGAQVPRLLKIEREDVQIKIQTNQWIAVAAKTK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RPOB_SALPB
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVVSKDYVDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIEEGNYVIAQANSNLDDEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MPC2_CAEEL
Sequence: MGPHRLLYQALCKAGDKFVYPVLPAFAKPAWNHAAGPKTVFFWAPTIKWTLIGAGLADLARPADKLSLYQNSALFATGAIWTRYCLVITPINYYLSSVNFFVMCTGLAQLCRIAHYRYQNPDWETKEIMETHN
What is the function of this protein?
May mediate the uptake of pyruvate into mitochondria.
What are the official names of this protein?
Probable mitochondrial pyruvate carrier 2, MPC2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EFTU_BURMS
Sequence: MAKEKFERTKPHVNVGTIGHVDHGKTTLTAAIATVLSAKFGGEAKKYDEIDAAPEEKARGITINTAHIEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYIIVFLNKCDMVDDAELLELVEMEVRELLSKYDFPGDDTPIIKGSAKLALEGDKGELGEVAIMNLADALDTYIPTPERAVDGAFLMPVEDVFSISGRGTVVTGRVERGVIKVGEEIEIVGIKATAKTTCTGVEMFRKLLDQGQAGDNVGILLRGTKREDVERGQVLAKPGSITPHTHFTAEVYVLSKDEGGRHTPFFNNYRPQFYFRTTDVTGSIELPKDKEMVMPGDNVSITVKLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_RHIE6
Sequence: MTRKQKRLAVIAGGMGFIIAAVLLVMFAFSQSVAYFYMPADLAKTPVAPETRIRLGGLVGAGSVVRGAGSTVEFTVTDGSANAVKVHYTGILPDLFREGQGVVTEGMFASAGNVFIADTVLAKHDETYMPKEVADKLKAQGLWQDGQGAQSQAGQGQGQEAKATR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: MDEP_STAAM
Sequence: MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
What is the function of this protein?
Involved in multidrug efflux.
What are the official names of this protein?
Multidrug resistance efflux pump SepA, Antiseptic resistance protein SepA, Staphylococcal efflux pump A.
What is the protein family that this protein belongs to?
Belongs to the multidrug resistance efflux pump SepA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACT1_PHYIN
Sequence: MADDDVQALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPKHLGIMVGMDQKDAYVGDEAQSKRGVLTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANRERMTQIMFETFNVPAMYVNIQAVLSLYASGRTTGCVLDSGDGVSHTVPIYEGYALPHAIVRLDLAGRDLTDYMMKILTERGYSFTTTAEREIVRDIKEKLTYIALDFDQEMKTAAESSGLEKSYELPDGNVIVIGNERFRTPEVLFQPSLIGKEASGIHECTFQTIMKCDVDIRKDLYCNIVLSGGTTMYPGIGERMTKELTALAPSTMKIKVVAPPERKYSVWIGGSIQSSLSTFQQMWISKAEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RLME_BUCBP
Sequence: MSKKRSSSSNRWLNEHFKDKYVKQVHKNKSDIRSRAWFKLDDIQSSNNFLKVGMTVVDLGSSPGSWSGYAVKRVGKKGRVIACDMRPMLPIKDVVFFQGNIKNKCFFNFIETYLCHKKVHVIISDMAPNMTGHYFIDHIQAILLSKLALKMSIKVLSKGGSLLVKSFYGQEFNSFIQDVHVTFSKVKICKPNSSRARSREVYILASGRKM
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIN11_YEAST
Sequence: MLQYIPLSNLPYSHIPLHHPSLTISTKCTRIIMHGTCLSGLYPVPFTHKVHHYPHFNIYISFGDPKYCITALNTYVIPLLHHILTTQFIHTYFNIPTKSPPKSPKHKNYLSFNFTK
What are the official names of this protein?
Putative UPF0320 protein YLL065W, Growth inhibitory protein 11, GIN11.
What is the protein family that this protein belongs to?
Belongs to the UPF0320 family.
Protein: GRCA_ACTSZ
Sequence: MIKGIQITQAANDSLLNSFWLLDSDKGEARCLAAKSGFAEDQVVAVSELGQFEYRELPLDVQPSVKVEGGQHLNVNVLRRETLEDAVKHPENYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: RL13_PHOPR
Sequence: MKTFVAKPETVKRDWYVVDAEGKTLGRLATQIASRLRGKHKPEYTPHVDTGDYIVVINAEKVAVTGAKRTDKMYHHHTGFIGGLKSISFEKLIDKKPEMVIETAVKGMLPKGPLGRAMYRKLKVYAGTEHNHAAQQPKVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: EMAL2_MOUSE
Sequence: MSSFGIGKTKEVIFSMEEGSVKMFLRGRPVPMLIPDELAPTYSLDTRSELPSSRLKLDWVYGYRGRDCRANLYLLPTGEVVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAVHPDMVTIATGQVAGTTKEGKPLPPHVRVWDSVSLSTLHVLGLGVFDRAVCCVAFSKSNGGNLLCAVDESNDHVLSVWDWAKESKVVDSKCSNEAVLVATFHPTDPSLLITCGKSHIYFWSLEGGSLSKRQGLFEKHEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNRITQEVQGAHDGGVFALCALRDGTLVSGGGRDRRVVLWGSDYSKVQEVEVPEDFGPVRTVAEGRGDTLYVGTTRNSILLGSVHTGFSLLVQGHVEELWGLATHPSRAQFVTCGQDKLVHLWSSETHQPVWSRSIEDPARSAGFHPSGSVLAVGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSTCFVTNSGDYEILYWDPVTCKQITSADTVRNVEWATATCVLGFGVFGIWPEGADGTDINAVARSHDGKLLVSADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVA
What is the function of this protein?
Tubulin binding protein that inhibits microtubule nucleation and growth, resulting in shorter microtubules.
What are the official names of this protein?
Echinoderm microtubule-associated protein-like 2, EMAP-2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EMAP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with the microtubule cytoskeleton. Colocalizes with the mitotic spindle.
Protein: VSP2_GLOUS
Sequence: VIGGDECNINEHRFLVAXY
What is the function of this protein?
Thrombin-like snake venom serine protease that cleaves alpha-chain of fibrinogen (FGA) releasing fibrinopeptide A.  Has high clotting activity.
What are the official names of this protein?
Thrombin-like enzyme calobin-2, SVTLE, Calobin II, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS8_SYMTH
Sequence: MVVSDPIADLLTRIRNANLAYHDRVDVPGSKMKKAIVQIMKDEGFIRDFEWIDNGHQGVIRIYLKYGPNKTRVISGLRRISKPGLRVYAKRDQIPRVLGGLGIAILSTSKGVMTDKQARQQGLGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PMGT2_CANLF
Sequence: MHLSAVLNALLVSVLAAVLWKHVRLREHAAALEEEVAAGRQAPAPGPAPRADYARALQLLSEGGTHMVCTGRTHTDRVCRFKWLCYSNEAEEFIFFHGNASVMLPNLGSRRFQPALLDLSTVEDHNTQYFNFVELPAAALRFLPKPVFVPDVALVANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAHEARLFFMEGWSEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKVTTWYQYGFVQPQGPKANILVSGNEIRQFARFMMEKLNVSQAGAPLGEEYILVFSRTQNRLILNEAELLLALAQEFQMKTVTVSLEDQAFADVVRLVSNASMLVSVHGAQLVTALFLPRGATVVELFPYAVNPDHYTPYKTLATLPGMDLQYVAWRNMMPENTVTHPERPWDQGGIAHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTVRRVVKGRPGPRKQKWTVGLYPGKVREARCQASVQGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILALQNHTFTENIKPFTTYLVWVRCIFNKTLLGPFADVLVCNT
What is the function of this protein?
O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein.  Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity).
What are the official names of this protein?
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, POMGnT2, Extracellular O-linked N-acetylglucosamine transferase-like, Glycosyltransferase-like domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 61 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: YUGH_BACSU
Sequence: MTSYLSDYVQQIKPSGIRKFFDLAATMEGVISLGVGEPDFVTAWNVREASILSLEQGYTSYTANAGLYSLREEISRYLSNRFDLSYSPDNELIVTVGASQALDIAIRAIVNPGEEVIIPEPCFVAYDALVSLAGGIPVHVHTTADKGFKATAADFEAAVTEKTKAILICSPSNPTGSVYSKEELNEIAEFAKKHDVIVLADEIYAELTYDEEFTSIAALPGMKERTVVISGFSKAFAMTGWRLGFAAAPSLLRDAMLKIHQYAMMCAPAMAQFAALEGLKNGMEDVEKMKKSYRRRRNLFVESLNEIGLSCHHPGGAFYAFPSIKSMGMSSEQFAEELLTQEKVAVVPGSVFGPSGEGYIRCSYATSIEQLQEALVRMKRFLHKTT
What are the official names of this protein?
Putative aminotransferase YugH.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_MYCS2
Sequence: MTEFRSGFVCFVGRPNTGKSTLTNALVGQKVAITSNRPQTTRHTIRGIVHREDFQIILVDTPGLHRPRTLLGQRLNDLVKDTYSEVDVIGMCIPADEAIGPGDRWIYQQIRAVAPRTTLIGIVTKIDKVPKDRVAAQLLAVSELMGPDAEIVPVSATSGEQLDVLTNVLVSQLPPGPAYYPDGELTDEPEEVLMAELIREAALEGVRDELPHSLAVVIDEVSQREDRDDLIDVHAILYVERDSQKGIVIGKGGARLREVGTAARKQIEKLLGTKVYLDLRVKIAKNWQRDPKQLGKLGF
What is the function of this protein?
Exhibits GTPase activity (PubMed:35917161).  Binds RNA but is probably not involved in ribosome assembly in mycobacteria (PubMed:35917161).  Cannot use ATP (PubMed:35917161).
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.