PharMolix/UniProtQA huggingface dataset:
Protein: SWI6_SCHPO
Sequence: MKKGGVRSYRRSSTSKRSVIDDDSEPELPSMTKEAIASHKADSGSSDNEVESDHESKSSSKKLKENAKEEEGGEEEEEDEYVVEKVLKHRMARKGGGYEYLLKWEGYDDPSDNTWSSEADCSGCKQLIEAYWNEHGGRPEPSKRKRTARPKKPEAKEPSPKSRKTDEDKHDKDSNEKIEDVNEKTIKFADKSQEEFNENGPPSGQPNGHIESDNESKSPSQKESNESEDIQIAETPSNVTPKKKPSPEVPKLPDNRELTVKQVENYDSWEDLVSSIDTIERKDDGTLEIYLTWKNGAISHHPSTITNKKCPQKMLQFYESHLTFRENE
What is the function of this protein?
Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.  Involved in the repression of the silent mating-type loci MAT2 and MAT3.  May compact MAT2/3 into a heterochromatin-like conformation which represses the transcription of these silent cassettes.
What are the official names of this protein?
Chromatin-associated protein swi6.
What are the subcellular locations of this protein?
Nucleus.
Protein: TOP2M_CAEEL
Sequence: MHRLRVLRHLKFCISTSHRTTVVLKNTRSFCNNIPSTSFASEAAAKYEKKSPTEHVLLRPDTYIGGVAMREDQIIWLRDSENRKMIAKEVTYPPGLLKIFDEILVNAADNKARDSSMNRLEVWLDRETARISVWNNGSGLPVEIHPTEGIYVPTLVFGNLFTSSNYDDSEIKTVGGRNGYGAKLCNIFSKEFIVETVDTRIKRRFRQKWYDNMKKCNEAEVVEILDETVKDYTKVEFVPDLERFQIDKLSDDVIDLIGRRVFEVAATLPRDVDVYLNGQKCDVDGFEDYVKMFNDSSSLLFLHPTPRWHVGVAKRNNFFGESHVVLPKIVSFVNNINTEKGGSHVDYVMDKIVNIIKPIVDSKLGDPTKSVKPAVIKNNLSIFINCLIENPSFESQTKETLTTKAKNFGSIFECDAKKTAEWAEQSGLIEDIVEEVLNMKKKKLPGKRVSVSSVRDIVKLEDAEWAGITGTAEKCTLILTEGDSAKALALAGLEVLGRETYGVFPLKGKLLNVSNLDDARASKNEEISNLLRILGLKFEDSNSITRESLRYGRLLILADQDEDGSHIKGLIVNFIHKFWPSLVHTDGFIQSFRTPLLKAKKGDKVRSFFSMNEYRKWADVEEGGKWKIKYYKGLGTSTSNEAREYFSDLDHHTVNFKYTGTTDDDAIRMAFDRDKSDERKEWIRRSENEITNEDDGKTEISYQEFVDGQLMQFGMVDLKRSIPSLIDGLKPSQRKILWTLLNNMDESTEIKVSQLAGAVAHRQSYHHGEESLVRTIIRMGQTFCGSSNLPLLQPIGQFGTRHEGGNDAASARYIFTALAPTTRLLFPQADDDLLQKNVEEGMVVEPTWLCPIVPLILINGTEGIGTGWSTKIANRNPIDIIDMIRRKIDSISTEYEIPPFYEEFRGKLEVVTPTKFISSGKIQLIRPERKNASTFSIEIVELPIGIWTSKYKEKLSKIVETLPVLEFSERHTEKRVHFRITLDRKKSSRFLQKSNSDLLNYFKLRTSLTENRVLFDRNGELKEFGNISEIAAEFFEVRRDLYEKRLKIQKEECEAKLIYVENQLNFIEMVTNGTIEIRSMGRNQLEEKLQEMGFRVDPMATIAKNSKKANYGYLLEMPVSRLTSDEMKRLEERKSRRRTELEAAESADWKSVWRSELDKLAEAVGNNRKS
What is the function of this protein?
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands.  Topoisomerase II makes double-strand breaks (By similarity).
What are the official names of this protein?
Putative DNA topoisomerase 2, mitochondrial, DNA topoisomerase II.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PGK_SYNFM
Sequence: MKTVGELELSGKRVFIRVDFNVPLDKEFRVKDDLRIRAVLPTLNKVIEKGGKAILASHLGRPKGKPSAEFSLKPVGEHLSRLIDRPVPLAPDCTGREVVERIAQMKNGDVLLLENLRFHAEEEKNDEAFSRALADLADVYVNDAFAVSHRAHASVHGMTRFARECAAGYQLENEIKYFRKAMDNPARPMAMVIGGAKVSTKIGVLEHLISRVDFLVIGGAMANTFFKAQGKEVGRSLVEDDHLETAARLLKAAAEKGVKVYLPVDAVVAPSLESCGDVQQVPVEKVPKDRLILDVGSKSIEVFESVLKNCRTIVWNGPLGAFETPPFNKGTFALAEFLGSLDALTVIGGGDSAAAVKQANMEDKVSYVSTGGGAFLEMLEGITLPGVAALEECCGRS
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_BLOPB
Sequence: MYKKIEIFTDGSCLGNPGPGGCAAILRYKQHKKEFSIGYRLTTNNRMELMAAIIALESLKNPCQIILNTDSQYLLHGITQWIHIWKKHHWKTSEEKLVKNIDLWQRLDVAIQIHSIIHWNWLKSHTGHPDNERCDQLARLAAKCPINEDFY
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIPD_SALTI
Sequence: MLNIQNYSASPHPGIVAERPQTPSASEHAEIAVVPSTTEHRGTDIISLSQAATKIQQAQQTLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQNENLRSTFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVYTDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGMTTATKAEAEQWIKELNLPDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLVKVLSSTISSSLETAKSFLQG
What is the function of this protein?
Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization.  Probably acts by modulating the secretion of SipA, SipB, and SipC (By similarity).
What are the official names of this protein?
Cell invasion protein SipD, Salmonella invasion protein D.
What is the protein family that this protein belongs to?
Belongs to the invasin protein D family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS).
Protein: FRDD_SALCH
Sequence: MINPNPKRSDEPVFWGLFGAGGMWGAIIAPVIVLLVSIMLPLGLFPGDALSFERVLTFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTAIGVITL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SETB1_XENLA
Sequence: MELEQMVVKELGISMDDLRELIDRELEKIEFVKQRKAQLLEMEQLVKQKEAEVDHVDKLFDNATRAVDDCETLVKSLYDQIGMTYKESSSEDEGSSKPTEVIEIPDEDDDDVMSVGSGEAVSKIPKEKHLLREAMAAMKRSRQDVQSIVEAIQKKSDGPQTRFSSHPSSPTSSVGGSNQASASNDMSKDGDLVVGMRILGKKRTKTWHKGTLISIQCVGTGKKFKVKFDNKGKSLLSGNHIAYDYHPPPENLTVGSRVVAKYKDGNQVWLYAGIVAEPPSSKNKMRYLIFFDDGYASYVTHAELYPVCRPWSKSWEDIEDVSCRDFIQEYVNAYPNRPMVLLKSGQLIKTEWEGTWWKSKVEEVDGSLVKILFLDDKRCEWIYRGSTRLEPMFSMKTSNASTQEKQQAGQQRTRPNVGAIRSKGPVVQFTHDLTGNEPEHNPAAPPSPQSMPSPQLIDTDSDSQQAQSKKQVAKKSTSFRPGSAGSGQSSPIPTESVPQPPAAPRPFQSNQSVQPVQSIQPIQPIHNIQTIQTIQGIQTIQAIQPIQSIQTLQPIQTIQPLQTIQTLQGNRIVTSIQQFQIIRTENIPAESTYKAPKEKLFYLPHVCNYTCLSRIRPLSHRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKSPCGLSLRTMPEIERYLFETQCKMLFLEMFCLDPYVLVDRKFQPQKPFYYIPDITYGKEDVMLSCVNEIDRTPPPQVAYSKERIPGKGVFINTGADYLVGCDCTDGCRDKSKCACHQLTIQATACTPGAQSNPMAGYQHKRLEECLPTGVYECNKRCKCSANMCNNRLVQHGLQVRLQLFKTQNKGWGIRGLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAKSSSDSSGVDLKEDHEENSGSEDQEESNDSSDDNFGKNEDITTSSVWRSYATRRTTRGQKENGTSETASKDSRTRDETTDCKLPEETSKNKVASWLSSNTMADSVMDSDSRSSLKMGEALETDKPKESEEASKYPRFAEGNRAYGYNPTPTKKDGVRRPVTKTALHQIKRQSSSAQPTEEVLTLSSSSDSEVGSGTNGSKKPAAQATANDSDDIQTISSGSDEEEEKKNVAASAGPVKRQVAVKSTRGFALKSTHGITVKSNMASGEGGPGRRNTRQFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKKLLCCCGSTECRGRLL
What is the function of this protein?
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3.  H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones.  Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.  H3 'Lys-9' trimethylation is coordinated with DNA methylation.  Plays a role in promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) or other tumor-related genes.  Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs).  Associates at promoter regions of tumor suppressor genes (TSGs) leading to their gene silencing (By similarity).
What are the official names of this protein?
Histone-lysine N-methyltransferase SETDB1, SET domain bifurcated 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with non-pericentromeric regions of chromatin. Excluded from nucleoli and islands of condensed chromatin (By similarity).
Protein: KR511_HUMAN
Sequence: MGCCGCSGGCGSGCGGCGSGSGGCGSGCGGCGSSCCVPICCCKPVCCCVPACSCSSCGSCGGSKGGCGSCGSSKGGCGSCGCSQSNCCKPCCSSSGCGSFCCQSSCSKPCCCQSSCCQSSCCKPCCCQSSCCQSSCFKPCCCQSSCCVPVCCQCKI
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 5-11, Keratin-associated protein 5.11, Ultrahigh sulfur keratin-associated protein 5.11.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 5 family.
Protein: MATK_EUCGL
Sequence: MEEFQGYFELDRSRQHDFLYPLLFREYIYALAHDHGLKKSILFENAGYDNKSSSIIVKRLITRMYQQNPLIFSANDSIQNPFFGQNKNFYSQIISEGFAVIVEIPFSLRLVSSLERKEIAKSHKLRAIHSIFPFLEDKFSHLDYVSDVLIPYHIHLEILVQTLRYWVNDASSLHLLRFFLHEYWNSLITQKNHITIFSKGNPRLFLFLYNSHICEYEYFFLFLRNQSSHLRSTSSGIFFERIYFYVKIEHFVKVFFDNDFQCILWFFKDPFMHYVRYQGKSILASKDTPLLMKKWKYYLVNLWQYHFYVWFQPGRIDINQLCKYSLYFLGYRSSVRLNSSVVRSQMLENSFLINNAMKKFETIVPIIPLIGSLSKANFCDTLGHPISKPTRADSSDSDIIDRFLRISRNLSHYHSGSSKKKSLYRVKYILRLSCVKTLARKHKKTVRTFLKRLGSEFLEEFLTEEEVVLSLIFPRTYSTSRRLYRGRIWYLDITSINDLVNYE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSMA_SHEDO
Sequence: MSNKVHLGHTARKRFGQNFLTDDSIISRIVGAISPDNDHVMVEIGPGLGAITEPVAMSIDKLSVVELDRDLVERLQNHPTLKDKLDIHQGDALQFDFSTLQQAGKKMKVFGNLPYNISTPLMFHLFEFAEIIETMHFMLQKEVVLRLSASPGCKAYGRLTVMAQYYCQVVPVLEVPPHSFTPAPKVDSAVVRLLPYANKPWPCKDVTVLRHLCTTAFNMRRKTLRNNLKQLISDEEFGLLNIDASLRPEQISVEQYVALANLLCDKQ
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOAI_ECO57
Sequence: MNDQMFVETLIITSSFFAIAVVLVLSVLLIERTG
What are the official names of this protein?
Uncharacterized protein YoaI.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NNF1_SCHPO
Sequence: MTSRKEQLDAFLSRTLSETIAHIPLEKFAQCFPSMKKGKVIAVIHQQLIEFFEKSCKQEYANLIKERDLNKKLDMLDECIHDAEFRKLHGESEVDISNKQPQEILKAHLYSHKRELLDKLNQDLLDIDKENEGLSTQIAAGRKSN
What is the function of this protein?
Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle.
What are the official names of this protein?
Kinetochore protein nnf1, NMS complex subunit nnf1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
Protein: HIS2_PHOLL
Sequence: MLTAQQIEKLDWEKVAYMMPVIVQHAISGDVLMMGYMNKEALNITISSGKITFFSRSKQRLWTKGESSGHFLNLVNIYPDCDNDTLLALADPIGPTCHFGTHSCFAPAQTEWGFLYQLEKLLASRKTADPDHSYTAKLYASGTKRIAQKVGEEGLETALAAAVNNREELTNEAADLMYHLMVLLQDQELDLSCVIRRLRER
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_SHELP
Sequence: MSEKKINLLDLDRKGLRALFTEMGEKPFRADQLMKWLYHFGVSDFEQMTNINKVLRAKLAARCEVVAPEISSYQKSADGTIKFAINVGNGQEVETVYIPEEDRATLCVSSQVGCALECTFCSTAQQGFNRNLTVSEIVGQIWRVSHFLGFQKETGERPISNVVMMGMGEPLLNLKNVMPAIDIMLDDFGFSLSKRRVTVSTSGVVPALDILGDNLDVALAVSIHAPNDELRDVLVPVNKKYPLQEFLAAIRRYLAKSNANRGRVTLEYVMLDHINDSTDQAHELAELMKDTPCKINLIPFNPYPGSPYGRSSNSRIDRFSKVLMEYGLTVIVRKTRGDDIDAACGQLAGDIRDRTKRLAKKRMQDSQISVTIN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_DROME
Sequence: MGPSHIPPLTYKVVAECSVSKARAGLMTLRHSEVNTPVFMPVGTQGTLKGIVPDQLIELNCQILLGNTYHLGLRPGIETLKKAGGLHKFMGWPRAILTDSGGFQMVSLLQLAEIDEHGVNFRSPFDNSQCMLTPEHSIEIQNAIGGDIMMQLDDVVKTTTTGPRVEEAMERTIRWVDRCIEAHARDDDQSLFPIVQGGLDVPLRQRCVSALMERQVRGFAVGGLSGGESKHDFWRMVDVCTGYLPKDKPRYLMGVGFAADLVVCVALGIDMFDCVFPTRTARFGCALVDSGQLNLKQPKYKLDMEPIDKDCDCSTCRRYTRSYLHHIATNESVSSSLLSIHNVAYQLRLMRSMREAIQRDEFPQFVADFMARHFKAEPVPAWIREALSAVNIQLPADPERIDEQDQKPKTEKRRETEDVAEEQVASS
What is the function of this protein?
Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
What are the official names of this protein?
Queuine tRNA-ribosyltransferase catalytic subunit, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_STAAE
Sequence: MSAIIEAKKQLVDEIAEVLSNSVSTVIVDYRGLTVAEVTDLRSQLREAGVEYKVYKNTMVRRAAEKAGIEGLDEFLTGPTAIATSSEDAVAAAKVISGFAKDHEALEIKSGVMEGNVITAEEVKTVGSLPSHDGLVSMLLSVLQAPVRNFAYAVKAIGEQKEENAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SPX_STRP8
Sequence: MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMSILSFTENGTEDIISTRSKVFQKLDIDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQIGFNEDEIRAFLSRDYRKQELRQATIKAEIEG
What is the function of this protein?
Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes.  Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP).  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
What are the official names of this protein?
Global transcriptional regulator Spx.
What is the protein family that this protein belongs to?
Belongs to the ArsC family. Spx subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_THET2
Sequence: MRLDTRFLSGFPEALSRHGPLLEEARRRLLAKRGEPGSMLGWMDLPEDTETLREVRRYREANPWVEDFVLIGIGGSALGPKALEAAFNESGVRFHYLDHVEPEPTLRLLRTLDPRKTLVNAVSKSGSTAETLAGLAVFLKWLKAHLGEDWRRHLVVTTDPKEGPLRAFAEREGLKAFAIPKEVGGRFSALSPVGLLPLAFAGADLDALLMGARKANETALAPLEESLPLKTALLLHLHRHLPVHVFMVYSERLSHLPSWFVQLHDESLGKVDRQGQRVGTTAVPALGPKDQHAQVQLFREGPLDKLLALVIPEAPLEDVEIPEVGGLEAASYLFGKTLFQLLKAEAEATYEALAEAGQRVYALFLPEVSPYAVGWLMQHLMWQTAFLGELWEVNAFDQPGVELGKVLTRKRLAG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_ANOFW
Sequence: MPKMKTHKGSAKRFKKTGTGQLKRSHAFTSHLFANKTQKQKRKLRKATLVSKGDFKRIRQLLDNVK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL10_LISMO
Sequence: MSKVLEAKQSAVEEIKTKLSASASTVIVDYRGLNVGEITDLRKQLRDAGIEFKVYKNSLTRRAVEANGYEGLEGALTGPNAIAFSNEDVVAPAKILNDFAKDHEALEIKAGVIEGKVASLEEIKALATLPSREGLLSMLCNVLQAPVRGLAIATKAVADQKEGQEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL36_LACLC
Sequence: MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: IHFA_BRUA1
Sequence: MGGKTVTRADLAEAVYRKVGLSRTESAALVEMILDEVCDAIVNGETVKLSSFATFQVRDKNERIGRNPKTGEEVPILPRRVMTFKASNVLKQRILQEHQKRQGKTSK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: LSPA_YERPP
Sequence: MNKPICSTGLRWLWLAVVVVILDISSKQWVMAHFALYESVPLIPFFNLTYAQNFGAAFSFLADKSGWQRWFFAGIAIGISVVLMVMMYRSTAKQRLINCAYALIIGGALGNLYDRLVHGAVNDFLDFYINNWHFPTFNLADVAICIGAALVIFEGFLSPVEKNAVNNDE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: INS_ALLMI
Sequence: AANQRLCGSHLVDALYLVCGERGFFYSPKGGIVEQCCHNTCSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ALGD_PSEAE
Sequence: MRISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQTGRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVVVRSTVLPGTVNNVVIPLIEDCSGKKAGVDFGVGTNPEFLRESTAIKDYDFPPMTVIGELDKQTGDLLEEIYRELDAPIIRKTVEVAEMIKYTCNVWHAAKVTFANEIGNIAKAVGVDGREVMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQLDVEHPMLGSLMRSNSNQVQKAFDLITSHDTRKVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYELRIFDRNVEYARVHGANKEYIESKIPHVSSLLVSDLDEVVASSDVLVLGNGDELFVDLVNKTPSGKKLVDLVGFMPHTTTAQAEGICW
What is the function of this protein?
Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization.  The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (Probable).  Other sugars are not used as substrates (PubMed:2470755).
What are the official names of this protein?
GDP-mannose 6-dehydrogenase, GMD, Guanosine diphospho-D-mannose dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: SHLD2_PONAB
Sequence: MSGGSQVHIFWGAPVAPLKMTVSQDTASLMSVADPWKKIHLLYSQHSLYLKDEKQHKNLENYEVPESVGSPDFSGHFLANCMNRHVHVKDDFVRSVSETQNIESQNIHSSRLSDITSSNMQICGFKSTVPHLTEEEKYQKLLSENKIIDEQPKHQSDICGQNFNTNLFQLGHKCAAMLDLVCSTEQINIGPEVVQRECVSTEYHEIQNQCLGLFSSNAVDKSRSEAAVRKASDLKISTDTEFLSIITSSQVAFLAQKKDKGRSPINKGNVNMETEPKASYREIRIPEENSIQLDGFTEAYEGGQNQAYSLELFSPVCRKTENSRIHINSDKGLEEHIGSQELFNSEDKLPPNEIHIELCSSGILCSQLNTFHKSAIKRSCTSEDKVGQSEALSRVLQVAKKMKLISNGGDSAVEMDRRNVSEFKGIKKTSLIKNCDSKSQKYNCLVMVLSPCHVKEINIKFGPNSGSKVPLATVTVIDQSETKKKVFLWRTAAFWAFTVFLGDIILLTDVVIREDQWVGETVLQSTFSSQLLNLGSYSSIQPEEYSSVVSDVVLQDLLAYVSSKHSYLRDLPPRQPQRVNSIDFVELEHLQPDVLVHAVLRVVDFTILTEAVYSYRGQKQKKVMLTVEQAQDQHYVLVLWGPGAAWYPQLQRKKGYIWEFKYLFVQRNYTLENLELHTTPWSSCECLFNDDIRAITFKAKFQKSAPSFVKIPDLATHLEDKCSGVVLIQAQISELAFPITAAQKIALNAHSSLKSIFSSLPNIVYTGCAKCGLELETDENRIYKQCFSCLPFTMKKIYYRPALMTVVDGRHDVCIRVESKLIEKILLNISADCLNRVIVPSSEITYGMVVADLFHSLLAVSAEPCVLKIQSLFVLDENSYPLQQDFSLLDFYSDIVKHGADARL
What is the function of this protein?
Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs).  During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection.  Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres.
What are the official names of this protein?
Shieldin complex subunit 2, Protein FAM35A, RINN1-REV7-interacting novel NHEJ regulator 2.
What is the protein family that this protein belongs to?
Belongs to the SHLD2 family.
What are the subcellular locations of this protein?
Chromosome.
Protein: YLBB_BACSU
Sequence: MTKIKDLMTADLQYCTVLDNVYEAAVKMKDANVGAIPVVDEDGETLVGIVTDRDLVLRGIAIKKPNSQKITDAMTEKPVSVEEDASVDEVLHLMASHQLRRIPVTKNKKLTGIVTLGDLSLSEQTNERAGSALSDISEGDNREEGFFH
What are the official names of this protein?
Uncharacterized protein YlbB.
Protein: NQRD_VIBAN
Sequence: MSSAKEIKKSILAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTLAVMFVTAFSNLFVSLIRHHIPNSVRIIVQMAIIASLVIVVDQILRAYLYDISKQLSVFVGLIITNCIVMGRAEAFAMKSAPIPSFIDGIGNGLGYGFVLITVGFFRELLGSGKLFGMEVLPLVKDGGWYQPNGLMLLAPSAFFLIGFMIWAIRTFKPEQLEAKE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.