PharMolix/UniProtQA huggingface dataset:
Protein: OBG_GRABC
Sequence: MKFLDQAKIYVKSGDGGDGVIAFRREKYIEFGGPDGGNGGRGGDIIVEAVANLNTLIDFRYTQHFRAPKGGNGAGSDRTGAAAPDVLIKVPVGTQILEDDRETLIADLDVPGKRITLCRGGDGGHGNAHFKSSTNRAPRRADKGWPGEERWVWLRLKLIADAGLVGLPNAGKSTFLSVVSAARPKIADYPFTTLHPQLGVVRLSLQEEFVLADIPGLIEGAHEGAGLGDRFLGHVERCAVLIHLIDGAAGDVVKAWRTVREEMEGYGGGLTEKPEIIVLNKCDGMTPREASARRSALAKASGQTVTVISGVTGEGVQPLLRQVMTYVAQSREERRKAMSGTSA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_STRS7
Sequence: MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGESTVLTAAVMSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFIINPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQEEIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAVQVEEKKAREAATEAVKEQVMAAYEERYAEDEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEIDFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGETGRYGAAGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITALQMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVDKIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKVGEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTANVSDVLEIGEEVDVKVIKVDDKGRIDASMKALVPRPPKPEKSEAKKEGKHD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPXC_RHIRD
Sequence: MIANSSTDVSVADQKFLNVAKSNQIDPDAVPISRLDSEGHSIFAEWRPKRPFLRREDGIFLVLRADHIFLLGTDPRTRQIETELMLNRGVKAGAVFDFIDHSMLFSNGETHGKRRSGLSKAFSFRMVEALRPEIAKITECLWDDLQKVDDFNFTEMYASQLPALTIASVLGLPSEDTPFFTRLVYKVSRCLSPSWRDEEFEEIEASAIELQDYVRSVIADSGRRMRDDFLSRYLKAVREAGTLSPIEEIMQLMLIILAGSDTTRTAMVMVTALALQNPALWSSLRGNQSYVAAAVEEGLRFEPPVGSFPRLALKDIDLDGYVLPKGSLLALSVMSGLRDEKHYEHPQLFDVGRQQMRWHLGFGAGVHRCLGETLARIELQEGLRTLLRRAPNLAVVGDWPRMMGHGGIRRATDMMVKLSFDL
What is the function of this protein?
Not essential for virulence, but may be involved in the detoxification of plant protective agents at the site of wounding.
What are the official names of this protein?
Cytochrome P450-pinF1, plant-inducible.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: SYM_BIFA0
Sequence: MSHIMVNVAWPYANGPRHIGHVAGFGVPSDVYARYQRMKGNDVLMVSGTDEHGTPILVEADKEGVTPQELANRYNRVIANDLCNLGLSYDLFTRTTTKNHEHVVQEMFRQCLANGYIYKGTQKVAISPSTGRTLPDRYIEGECPICHAQGARGDQCDNCGNELDPDELINPVSKINGETPIFEETEHYFLDLPALAEANLAWLKTRKGWRPNVLNFSIGLFKEVKPRAITRDIDWGIPVPVPGWIDNPNKRLYVWFDAVIGYLSASIEWARRSGDPEAWRAWWNDPATPGYYFMGKDNITFHSQIWPSEMLAYNGEGSKGGEPGELGRLDLPEQVVASEFMTMEGKKFSSSRGIVIYVKDILSRYPVDAVRYYISAAGPESSDSDFTWAEFVRQNNEVLAASWGNLVNRVANLIAKNFGQIPPIVEEKMTDEDRALLAQSSAAFDTVGALIEQHRQKSALNDAMSLVGDINKYISATEPWKIKDDPERLGTVLHVAAQAVSDANHLLAPFLPHSSQKVWEALGGEGTFSPLPHIEEVNDLDDPEFTYPVITGKYVLGENVHPWKSEPIVVGAPVVKPTPIFAKIPPEAVDEELARFDADLKARREAEQARLDAEKAKLAAGEE
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDC3_SCHPO
Sequence: MKDNQQAVQLQQPTTIGHYLAVRLAQAGVKHHFVVPGDYNLGLLDKLQYNNYLEEVNCANELNCAFAAEGYARANGIAACVVTYSVGAFTAFDGIGGAYAEDLPVILISGSPNTNDIGSSHLLHHTLGTHDFSYQYEMAKKITCAAVSIQRPTEAPRLIDYAIKMALLKKKPVYIEVPTNVASQPCAAPGPASLITEPETSNQEYLQMAVDISAKIVNGKQKPVLLAGPKLRSFKAESAFLELANSLNCSVAVMPNAKSFFPESHPNYAGIYWGQASTLGAESIINWSDCIICAGTTFTDYSSNGWTSLPPKANVLHVDVDRVTVSDAEFGGVLLRDFLHELAKKVKANNASVVEYKRIRPESLEIPMENPKAALNRKEIIRQVQNLVNQETTLFVDTGDSWFGGMRITLPEKARFEIEMQWGHIGWSVPSAFGYAIGAPKRNVVVFVGDGSFQETVQEVSQMVRLNLPIIMFLINNRGYTIEVEIHDGPYNRIKNWDYAAIVEAFNAGEGHAKGFRVGNGHELAEAIRQAKENSQGPTLIECNIDQDDCSKELINWGHNVGAANGKPPAKE
What are the official names of this protein?
Probable pyruvate decarboxylase C186.09.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: OOEP_CANLF
Sequence: MVDDAGAAEVLGDEWRPAWSLDRLLRAPLPPPRIRTRPWWFPVQELRDPLVFYLEAWLADAIFGPDRAIIPEIEWMSQVLLTVDVVNSGDLVEISIFGWPRVQNRVKSVLLSLASWHRKHRARAEKMKQLEEFLKTGGTGPQTPEHPVA
What is the function of this protein?
As part of the OOEP-KHDC3 scaffold, recruits BLM and TRIM25 to DNA replication forks, thereby promoting the ubiquitination of BLM by TRIM25, enhancing BLM retainment at replication forks and therefore promoting stalled replication fork restart (By similarity).  Positively regulates the homologous recombination-mediated DNA double-strand break (DSB) repair pathway by regulating ATM activation and RAD51 recruitment to DSBs in oocytes (By similarity).  Thereby contributes to oocyte survival and the resumption and completion of meiosis (By similarity).  As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (By similarity).  Required for the formation of F-actin cytoplasmic lattices in oocytes which in turn are responsible for symmetric division of zygotes via the regulation of mitotic spindle formation and positioning (By similarity).
What are the official names of this protein?
Oocyte-expressed protein, Oocyte- and embryo-specific protein 19, dOEP19.
What is the protein family that this protein belongs to?
Belongs to the KHDC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MSRB_STRP1
Sequence: METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: RLMN_ECODH
Sequence: MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFC4_DICDI
Sequence: MSKIQKKDTEPWVAKYRPKTVDDVSYQEDVISALKKSLNTGNLPHLLFYGPPGTGKTSTILAIAMDIYGPELMKQRVLELNASDERGIEVVRTKIKNFAGYAVNKTTTGTSNPGATFKLIILDEADSMTTDAQAALRRTIETTSKTTRFCLLCNYISRIIDPLASRCAKFRFKPLDTVATIERLKFISQQEGIKCEESVYQAIQVVSNGDMRKAITYLQSAFRFFANKISEDVIYNIAGSLPPQLIKQLVDCCKKNSFDRLQSMVQSIIAQGYPVSQVISQLFDYVLTTKDLNQSQKSHITMKIGNVDRNLIDGSEEFLQLFDLSSYIMKQLNNNSTSTNGDDMLIG
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1.  This subunit may be involved in the elongation of the multiprimed DNA template (By similarity).
What are the official names of this protein?
Probable replication factor C subunit 4, Activator 1 subunit 4.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CNFN_XENTR
Sequence: MSYPIGAQPQGVQGYVTSNSSQWNSDVFDCCEDMGICLCGTFVPCILACKVSQDFGECCCLPCLFGSVLAVRTGIRERYHIEGSICNDWVCLSFCGQCTLCQMARELKARN
What are the official names of this protein?
Cornifelin homolog.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
Protein: OMP10_AGRFC
Sequence: MNFKTSAALLSAAIAVSSCVAPGPSQQTSMAPSLSRGPAVDGRWIDRNGIISTFQNGAFSTRSTDTNTLLASGTYVTISPTLYEINMTSLVRNTQSRVNCALVSPSQLNCTTDANSQFSLTRQG
What are the official names of this protein?
Outer membrane lipoprotein omp10 homolog.
What is the protein family that this protein belongs to?
Belongs to the rhizobiaceae omp10 lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RIR1_PONAB
Sequence: MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKEAKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSSLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKLLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCSLENRDECLMCGS
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEAR1_HUMAN
Sequence: MSPPLCPLLLLAVGLRLAGTLNPSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQEPFTVMPTTPVAYNSLGAVIGIAVLGSLVVALVALFIGYRHWQKGKEHHHLAVAYSSGRLDGSEYVMPDVPPSYSHYYSNPSYHTLSQCSPNPPPPNKVPGPLFASLQNPERPGGAQGHDNHTTLPADWKHRREPPPGPLDRGSSRLDRSYSYSYSNGPGPFYNKGLISEEELGASVASLSSENPYATIRDLPSLPGGPRESSYMEMKGPPSGSPPRQPPQFWDSQRRRQPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPLRRQDR
What is the function of this protein?
When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells.
What are the official names of this protein?
Platelet endothelial aggregation receptor 1, hPEAR1, Multiple epidermal growth factor-like domains protein 12, Multiple EGF-like domains protein 12.
What is the protein family that this protein belongs to?
Belongs to the MEGF family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Detected on the cell surface in resting platelets.
Protein: FCL1_ARATH
Sequence: MAETIGSEVSSMSDKSAKIFVAGHRGLVGSAIVRKLQEQGFTNLVLKTHAELDLTRQADVESFFSQEKPVYVILAAAKVGGIHANNTYPADFIGVNLQIQTNVIHSAYEHGVKKLLFLGSSCIYPKFAPQPIPESALLTASLEPTNEWYAIAKIAGIKTCQAYRIQHGWDAISGMPTNLYGPNDNFHPENSHVLPALMRRFHEAKVNGAEEVVVWGTGSPLREFLHVDDLADACVFLLDRYSGLEHVNIGSGQEVTIRELAELVKEVVGFEGKLGWDCTKPDGTPRKLMDSSKLASLGWTPKVSLRDGLSQTYDWYLKNVCNR
What is the function of this protein?
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.  Not involved in the synthesis of GDP-L-galactose from GDP-D-manose.
What are the official names of this protein?
GDP-L-fucose synthase 1, GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase 1, AtFX, AtGER1.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
Protein: TPM_BRABE
Sequence: MDAIKKKMLMLKNDKENALDRAEQAEQAMKDAQEKNVKLEDEINDLNKKIRMVEDELDKAQESLKEATEQLEAATKKAADAEAEVASLNRRIQLVEEELDRAQERLNSTVEKLTDSEKAADESERARKVLENRQGADEDKMELLDMQLREAKMIAEEADRKYEEVARKLVITEGDLERAEERADLAETKARELEDELKTTTGQLKSMEAQATKASEKEEAYEEQVRDLSAKLKEAETRAEFAERTVAKLEKNVDDLEDALYAEKEKYRGVSEELDQALNELHNM
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: ISPG_CLAMS
Sequence: MPAVNLGMPKVPEVLAPRRKTRQISVGKVKVGGNAQVSVQSMTTTQTTNINATLQQIAELTATGCDIVRVAVPHQDDADVLHILAKKSQIPIIADIHFQPRYVFTAIDAGVGAVRVNPGNIRKFDDQVGAIAKAAKAAGTSIRIGVNAGSLHPSLLQKYGKATPEALVESAVWEASLFEEHDFHDFKISVKHNDPVIMVKAYRLLAERGDWPLHLGVTEAGPAFQGTIKSATAFGILLSEGIGDTIRVSLSAPPAEEVKVGLQILQSLNLRERKLEIVSCPSCGRAQVDVYSLAEQVTEGLKHVNVPLRVAVMGCVVNGPGEAREAELGVASGNGRGQIFVKGEVIKTVPESEIVQTLIEEANRLAAEMPAGSIGSPEILV
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: HUTG_GEOTN
Sequence: MYQPPEASCWTGRVDSVSDERAFRLHQRIRLLDLSGPLTPLEQAAAFIGFVCDEGVRRNQGRQGAKEAPAAVKAALARLPWHLPSGASIYDAGDIVCADGRLEQSQAELGKAIARLLQSGVAPVVIGGGHETAYGHYLGVRAALGPNARLGIINIDAHFDLRPYDNGPTSGTMFRQILDEDKQVGYCCLGIQRLGNTAALFADAERYGCEYILEEQLTAGAIEAAYERIEQFASRHDSVILTICMDAISAAAAPGVSAPSPFGLSPSLARALIRRIVSHPKTISVDLCEVNPLVDEGGKTVALAAAFCMEALLHFRRLQPRR
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: FPG_DINSH
Sequence: MPELPEVETVRRGLEPVMTGQRIIEADIRRPDLRWPLPANMQTRLEGKRILRLARRSKYILAELDSGETLIIHLGMSGRILIHGGQAPGAFHHALPSLEKHDHVVLDFDTGARVVFNDARRFGAMDLCETTEIDQHPMLATLGPEPLGNAFHEAYLTTRLKGRMTPIKSALLDQKVVAGLGNIYVCEALFQAGISPLRKAGRVSETRIASLVPIIRTVLGDAIEAGGSSLRDYRQTDGDLGYFQHRFRVYDRENAPCVTAGCPDVVRRVVQSGRSSFYCPSCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PSTA_XYLFT
Sequence: MSTASQHLYKRRRLINAAAITISCIAALFGLFFLIWILWTLISKGLPGIDLDLFTKITPPPMQKGGLANAFLGSAIMCLLAIVIGTPVGIAAGTWLAEYGNTSQTSTVVRFVNDILLSAPSIVLGLFVYTLYVMHTGGHFSAFSGALALVFIVLPIVVRTTDEMLRLVPGQMREAALSLGIPQWKMITQVLYRSASAGILTGILLALARISGETAPLLFTAFGNQYWSSNIFQPIASLPLVMNQFASSPYKSWQLLAWSGALVLTVFVLLVSLGARALLLRNKIPNT
What is the function of this protein?
Part of a binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Phosphate transport system permease protein PstA.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR19_DIOEL
Sequence: MTRSLKKNPFVVDHLSGKIEKLNMREEKEIIVTWSRGSTIIPAMMGHTIAIHNGKEHFPIYITDQMVGHKLGEFSPTLTFARHTRNDNKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RADL2_ARATH
Sequence: MASGSMSSYGSGSWTVKQNKAFERALAVYDQDTPDRWHNVARAVGGKTPEEAKRQYDLLVRDIESIENGHVPFPDYKTTTGNSNRGRLRDEEKRMRSMKLQ
What is the function of this protein?
Probable transcription factor.  Required for female gametophyte development.
What are the official names of this protein?
Protein RADIALIS-like 2, AtRL2, Protein RAD-like 2, Protein MATERNAL EFFECT EMBRYO ARREST 3, Protein RADIALIS-LIKE SANT/MYB 1, Protein RSM1.
What are the subcellular locations of this protein?
Nucleus.
Protein: XYLA_ECOHS
Sequence: MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNSELGQQILKGQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_ECOL6
Sequence: MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKAQAGVAQTAQDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRKINGSFHAVVGLPLVETYELLSNFNALREKRDKHDG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_POLSJ
Sequence: MMKKDAPRGTRTGFTTGACSAAAARAAVIGLVTGQVPDAVECLLPNGDLVTFAVQDGRVEGVGGGVGGGVSAHAMVIKDAGDDPDCTDKAHLTADVRLRHDLPGQVLLAGGFGVGTVTMPGLGLAVGGPAINPVPRRNIEANVRAVGQGLLDEVGLEVTISVPQGEEMTKKTLNARLGILGGISILGTTGIVKPYSTAAYRASVVQGVQVAGTLGHGVVVLTTGGRTEKFVMEEMPELPEPAFVQMGDFLRYAMGAAVKAGLKKVVIGGMVGKLTKIAQGETITHAGRAEVDTGLLAELAASVGAPPDVCDAIRGNETARYAGERMDALGLGQAFHTALAQRVIQTLRTRYPDQFELKVLVCDFDGRKIAEAS
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: CYFP1_MOUSE
Sequence: MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLADIVNLCVDYYENRMYLTPSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFKQLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCASSSSSPQYNICEQMIQIREDHMRFISELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPTDKYSNKDCPDNAEEYERATRYNYTTEEKFALVEVIAMIKGLQVLMGRMESVFNHAIRHTVYAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKTVCDWETGHEPFNDPALRGEKDPKSGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESFFYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTKFNKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSLELAIGRFESEDLTSVVELDGLLEINRMTHKLLSRYLTLDSFDAMFREANHNVSAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNLAYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKICRLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAVLFCLLIEQSLSLEEVCDLLHAAPFQNILPRIHVKEGERVDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRTFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCIPVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVPLKKMVERIRKFQILNDEIITILDKYLKSGDGESTPVEHVRCFQPPIHQSLASS
What is the function of this protein?
Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression.  In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1.  Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity).  Regulates formation of membrane ruffles and lamellipodia.  Plays a role in axon outgrowth.  Binds to F-actin but not to RNA.  Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex.  Actin remodeling activity is regulated by RAC1.  Regulator of epithelial morphogenesis.  May act as an invasion suppressor in cancers.  As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).
What are the official names of this protein?
Cytoplasmic FMR1-interacting protein 1, Specifically Rac1-associated protein 1, Sra-1.
What is the protein family that this protein belongs to?
Belongs to the CYFIP family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, lamellipodium. Cell projection, ruffle. Synapse, synaptosome. Note=Highly expressed in the perinuclear region (PubMed:11438699). Enriched in synaptosomes (PubMed:11438699). Also enriched in membrane ruffles and at the tips of lamellipodia (PubMed:14765121).