PharMolix/UniProtQA huggingface dataset:
Protein: Y2227_MYCBO
Sequence: MTVQNEPSAKTHGVILTEAAAAKAKSLLDQEGRDDLALRIAVQPGGCAGLRYNLFFDDRTLDGDQTAEFGGVRLIVDRMSAPYVEGASIDFVDTIEKQGFTIDNPNATGSCACGDSFN
What are the official names of this protein?
Protein Mb2227c.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: STT4_SCHPO
Sequence: MDCIDKSIRRESLRKLGCLPDHGWNLFVQSSNRYSKLLEADSKLFKAQRIEDTVLSICEVTLENKASENALTLFQQLRFYLLNYLFLEDTSEYKSVLCSLDESVYPNLLPLTANICPCILKALLALVRQHRELSSDIVKFLNSIFLALTRILNTPHSSNNNPTHTKTTIFEKVFYASHLGFFFEEIADACISALPQDACLWAMEVCNTILVSDLPCKLIDLHNDSFLHHSNYYAGFGLSYYLYLSSMKAYINSSGCLWYEDATSFWDIVKHRPSSPEEKPFLTQFQSILNLSDKFLSKTGTLRLQEKLGTSCNLFFVLVLKLALLSSSYIGFVPYTYSDWINVLLGSISEDPELLPHLIELMASLACVFPTHFQFAMKRLRLIAIYAPRFDDGNVTYAQLASRKLAQLFNYSSRDTAITSIYQFANLLSPADTPDSYLAAPKERLSISDNMSSSSSQTATVNTISNYLNVIDSVREIALTVNDEKIYGLAISLLIQKFSRKFDSRVSTELVRTLADISTKANDRDFSILVQFYSIQNKMLVKNGDEALTIAICDSRCLIARGTESNSFKRSDLLKSLLEEIIHIGIVRDTPAPELKGYYFGMSKAVQALVECVAGTDWSSLPKEEMYPALFRDMWFTLVINRFRYSVDLGETLEVDLENIAKNSPLLVFEDFGSNFESNLELNTVLRTHIEHSVISQIKSELLVRVPNIDLKPLSTSEICFLSAVLLLESLRCKSNKLSALVEYLLDPSLRDSQLPQSIRAIALYNLTSFVESLSKERRVASSTIDEFQKLLCLCCNRVDCVRQLALECMNYIMETLPHLLGIKEILFSVLELSSLLWKARTEECTDQYVPQLLYKSNKLNLSVILSDIYSCREEVLFQFNRHARSWIQNSSKAIPYQVKNLLESYLADFVDFDDLEVVELGRSLAVELGTRIVSSDRDNFVLPAFGNWTPDTSSEFMAEYTIRQRYSHVDNSILNIEGDMSTDRIDLILNEKSKLFETHLAALKSLEDDILQGNTVSPQRLRNEVRKAAAHAVQEPIFQFSVLARKIVRIPFLDFSPSSFKLGITLWNWMMNQVPSFSSFLISNIIRNWKNEIVTEKRGYFSTAKSKSPLALPMTYSPTERASFLSYKNKVMSQMIPHLLLLQLIAGNFEGFWYGDRQTAKLIVHFMKFVLKKITSMEVNLNVLTRELHFKFVSFGLRIAENLLNSPLGSRFYNLCVDAGLCWFSGMPNWTYGADKLHVAAEISVMRSLRDKLDSFLLRYPLKVSTTLKQKLLIILLNNEMYMLYTWLTPVLHGRNVRMVEPIPDSDAASSPITLEMLQVAWNVSPNIVLYAPKRFQNAPLKQMALNFVIANPFTSVKHEVALEYLFEHYPSGEFPIDRKFILYWEPMYPVSGPVMFMPNVKWNPQLLQYTMRSMESYPVSVTFFYVPQIVQSLRYDSMGYAESFILETSGTSQLFAHQILWNMKANLYKDEAATVPDSIKPILDRVMDKMINSLSGEDKQFYEREFTFFNEVTSISGKLKPFIRKSKPEKKAKIDEEMKKIKLDVGVYLPSNPDGVIVGIDRKSGKPLQSHAKAPFMATFKIRKEKLVDADPEELAVNGTEEEAGDSAKKQTYEVWQSAIFKVGDDCRQDVLTLQLIAMFKNIFNSVGLDVYLFPYRVTATNPGCGVIDVLPNCISRDMLGREAVNGLYDYFRTKFGDEDSIAFQKARSNFVQSMAAYSVITYLLQFKDRHNGNIMIDDQGHILHIDFGFIFDIAPGGITFESAPFKLTTEMIAVMGGSNKSQPFQWFQELCVKAFLACRPYAHYICQAVEVMLDSGLPCFKGQLTITHCLERFALNLNERQASTFMLHLIEQSYANKRTLMYDQFQKATNGIPY
What is the function of this protein?
Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,-trisphosphate.
What are the official names of this protein?
Phosphatidylinositol 4-kinase stt4, PI4-kinase, PtdIns-4-kinase.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTBL1_RAT
Sequence: MDVGELLSYQPNRGTKRPRDDEEEELKTRRKQTGPRERGRYREDEATAAEDADDDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFEKRSYKNQELRIKFPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELSAVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVREEADGVHNTLAIVENMAEFRPEMCTEAAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDALCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHAMIGPEGADNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLRGQQRTRLLNKFTENDSEKVDRLMELHFKYLGAMQVADKKIEGEKHDIVRRGEIIDNDMEDEFYLRRLDAGLFILQHICYIMAEICNANVPQIRQRVHQILNMRGSSIKIVRHIIKEYAENIGDGRSPEFRETEQKRILGLLENF
What is the function of this protein?
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.  Participates in AID/AICDA-mediated somatic hypermutation (SHM) and class-switch recombination (CSR), 2 processes resulting in the production of high-affinity, mutated isotype-switched antibodies.
What are the official names of this protein?
Beta-catenin-like protein 1, Nuclear-associated protein, NAP.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAT_HV112
Sequence: MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAPQGSQTHQVSLSKQPTSQSRGDPTGPKE
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: LON_ANADE
Sequence: MRERKETAMSDKEKKGAGAGAQVAPAMGPPVLINKEDIPAVLPILPLRNSVFFPGGVLPLAVGRQKTIALIKDAVRDEQVIGVVTQRRAEEEDPGAADLYTVGTVARVVKLLKMGEDNYSLVVQGLARFKVLELVQESPYLKARIEAVEDRSVVDDVEVEALAINLKKLAREVIELMPELPAAATELVESITHPGHLADLIAANVDVPIEEKQQVLETVELKARMKLVLELLNRKREILKLSNKIDSAVKGEMSKTQREYYLRQQLKAIKEELGELGEEEEELDELQERLKKAGLPPEVEKVAQKELNRLKSIPTASSEYTVARTYLDWIADLPWTKRTDDNLDIENARQILDTDHYGLDKIKKRILEYLAVRKLKNDMRGPILCFVGPPGVGKTSLGQSIARATGRKFVRLSLGGVRDEAEIRGHRRTYVGALPGRIIQSMKKAATVNPVMMLDEIDKLGADFRGDPSAALLEVLDPEQNHAFSDHYLDLSYDLSKVMFIGTANLLDPIPGPLKDRMEILELPGYTFEEKVHIAQNHLIPKQLREHGLSADAIAISEKALIKIIMAYTREAGVRNLERRIADVCRAIAVEVASGKIGASAKRSIEEADVLEILGPEKFYNETAERTEIAGVATGLAWTAAGGDILFIEATKMPGKGALTLTGQLGDVMKESAQAALSYLRSKSDSLGIPVNFLEKTDLHIHFPAGAIPKDGPSAGVTILTALVSLLTGIRVRSDVAMTGEVTLRGLVLPVGGIKEKVLAAHRAGIKRIIIPARNEKDLLDVPEQARKELEFVFAAHMDEVLQAALEENPVGRKPPAAPEPEGEKKPGATPTPPAKKPDEIRV
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_RHORT
Sequence: MTRKKRRLYFVVLGMLALFAAAGLTLTAFQDNLVFFYSPTDLQEKGVDQGRRFRVGGLVEEGSVVRDGETVRFIVTDLMNTVTVRYTGMLPDLFREGQGVVAEGAMDGAGTFVAASVLAKHDENYMPPEVAESLKASGKWQHGPPTAAAAPAP
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SODC_DROOR
Sequence: MVVKAVCVINGDAKGTVFFEQESSETPVKVSGEVCGLAKGLHGFHVHEFGDNTNGCMSSGPHFNPYGKEHGAPVDENRHLGDLGNIEATGDCPTKVSITDSRITLFGADSIIGRTVVVHADADDLGKGGHELSKSTGNAGARIGCGVIGIAKV
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn], Superoxide dismutase 1.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BORBR
Sequence: MPRVKRGVTARARHKKVIAAAKGYRGRRGNVFRIAKQAVMRAGQYAYRDRRNKKRTFRALWITRINAAVREQGMSYSVFIAGLKKAAIELDRKVLADLAVRDKAGFAAIVQQAKAALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ISPF_SHESM
Sequence: MKIRIGHGFDVHKFGEARPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDAAYKGADSRVLLRHCYALARAKGFELGNLDVTIIAQAPKMAPHIEDMRQVLAADLNADIADINVKATTTEKLGFTGRKEGIAVEAVVLLSRQ
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PGME_ASPTN
Sequence: MAETATRSDSGMFWKATTYKEQYWDGYLAARPKYSSDFYERIVDYYKAHNPSPPTPTVAHDVGTGPGQVASELCKYFDKVIASDPNSTHLAVASARNEKSGLNHKITWTEVSAEDLNSHYPAGSASFLAAAECLPLLDVPRALNTFAHLLHPNGTLAAWFYGRPVFSEPTVAAKCQPILNDIIDLTFEKVIKGAPPAHKTTWKRSTDTLYSFLDNVAFPTETWRDVYRFKWNPHLPLSVVGPNACDYPIEPSSCIDPEREKVVEAKDPHFWEEVWDIFEVRRFVECLLPNIEELKSKGVYDHVEVKYKELEEAMGGANAKKEITWPVVLILATRV
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of pleosporalin A, ascomycone A, as well as a third cryptic naphthoquinone derived pigment, all responsible for the coloration of conidia (PubMed:28471414, PubMed:35351612).  Essential for the production of pleosporalin A, but not the 2 other final products (PubMed:35351612).  The pathway begins with the biosynthesis of the cyclized heptaketide 3-acetonyl-1,6,8-trihydroxy-2-naphthaldehyde by the NR-PKS pgmA.  The C-6 hydroxyl group is further methylated by the O-methyltransferase pgmB to yield fusarubinaldehyde which is in turn oxidized by the cytochrome P450 monooxygenase pgmC at C-9.  The C-1 hydroxyl group is then methylated spontaneously.  Although pgmE, pgmD and pgmH are essential for the production of pleosporalin A, it is not the case for the 2 other final products and it remains difficult to assign a specific function to each enzyme.  PgmF and pgmG seem not to be involved in pigment biosynthesis although they were regulated by the cluster-specific transcription factor pgmR (PubMed:35351612) (Probable).
What are the official names of this protein?
Methyltransferase pgmE, Pigmented naphthoquinones biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: NDHI_PICAS
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPISIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RL13A_HUMAN
Sequence: MAEVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLMRLRKQAEKNVEKKIDKYTEVLKTHGLLV
What is the function of this protein?
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions (PubMed:14567916, PubMed:17218275, PubMed:23636399, PubMed:32669547).  Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes (PubMed:23071094).  Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation (PubMed:23071094).  In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex (PubMed:23071094).  Involved in methylation of rRNA (PubMed:17921318).
What are the official names of this protein?
60S ribosomal protein L13a, 23 kDa highly basic protein, Large ribosomal subunit protein uL13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROY_ECO57
Sequence: MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATIIIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVTVLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHDRQLAENQ
What is the function of this protein?
Permease that is involved in the transport across the cytoplasmic membrane of proline.
What are the official names of this protein?
Proline-specific permease ProY.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ULAC_SALTI
Sequence: MKLRDSLAENNSIRLQAEANTWQEAVKIGVDLLVAADVVEPRYYQAILDGVEQFGPYFVIAPGLVMPHGRPEEGVKKTGFSLVTLKKPLEFNHEDNDPVDILITMAAVDANTHQEVGIMQIVNLFEDEANFDRLRACRTAQEVLDLIDRTNAAA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIA component, Ascorbate-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG85_BPNF
Sequence: MYSFTAYANSDIVAFHLLKFLSSENNIEISYADEDTIPEYVSIRDLKAGDKTTIDLYPLVAWKVIAQEDITTGDRVSVGKNGQVKKTTDLRTAFGYAVSLAKAGQLVTVAISTVFDTIITPDDLGNVDDDVKAFLKSNATDANKAKLRDLLVSNLDVKAFLNGSTSEDNKINLRNLLVSNPAILAFLNANPDTDTQTTLRTMIGAGTPYTLPAATTTTLGGVKRIPAFGNSTATDVATLVKDFNNLLAAMRTAGYIL
What are the official names of this protein?
Head fiber protein, Late protein GP8.5.
What are the subcellular locations of this protein?
Virion.
Protein: RL30_BACFR
Sequence: MSTIKIKQVKSRIGAPADQKRTLDALGLRKLNRVVEHESTPSILGMVDKVKHLVAIVK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GMHA_NEIG1
Sequence: MTTLQERVAAHFAESIRAKQEAEKILVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQHFAAEMTGRFEKERMELAAVALTTDTSALTAIGNDYGFDHVFSKQVRALGRAGDVLVGISTSGNSANVIEAVKAAHERDMHVIALTGRDGGKIAAMLKDTDVLLNVPHPRTARIQENHILLIHAMCDCIDSVLLEGM
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHA_ECO8A
Sequence: MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPTFAPQNCTAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYSQGMTVVDYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA
What is the function of this protein?
Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: KDUI_ECO24
Sequence: MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDRIIVGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTIAVDGQCYEIGHRDALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: RBL_EXAAF
Sequence: DILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYGIEPVPGEEDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAINKAQAETGEIKGHYLNATAGTCEEMIKRAVFARGLGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLRKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEKDRSXGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGGDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAVEGNEIIREASKWSPELAAACEVWKEIRFNFKAVDTLDPLKS
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MZM1_AJEDR
Sequence: MAATPVPTALGAYRLLLRATRIAFHGDFTTLHAARAEARKQFDQHRELGVDTPMRIQHAVETAEILRTNVVQGIKVSDAGEDTDRYELRIHEHIERGDNDTIKTAGKNKKVKVAVGKTCSNTQS
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PG030_VARV
Sequence: MDTYMNRLDLDKLKHENIFSGNIIEDAKEFVFGSRKIYTDSVNDLIELYNLAKYLNNEKLKDVVIERMDYVCKYIIGKDNWYTIYSFYKENGLRNSFLRQYINNNIEEIRNTDQFLKFDVDSVCDILNNDETIV
What are the official names of this protein?
Protein OPG030.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG030 family.
Protein: SPT2_YEAST
Sequence: MSFLSKLSQIRKSTTASKAQVQDPLPKKNDEEYSLLPKNYIRDEDPAVKRLKELRRQELLKNGALAKKSGVKRKRGTSSGSEKKKIERNDDDEGGLGIRFKRSIGASHAPLKPVVRKKPEPIKKMSFEELMKQAENNEKQPPKVKSSEPVTKERPHFNKPGFKSSKRPQKKASPGATLRGVSSGGNSIKSSDSPKPVKLNLPTNGFAQPNRRLKEKLESRKQKSRYQDDYDEEDNDMDDFIEDDEDEGYHSKSKHSNGPGYDRDEIWAMFNRGKKRSEYDYDELEDDDMEANEMEILEEEEMARKMARLEDKREEAWLKKHEEEKRRRKKGIR
What is the function of this protein?
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053).  Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053).  Global regulatory protein that plays positive as well as negative regulatory roles in transcription (PubMed:2072912).
What are the official names of this protein?
Protein SPT2, Negative regulator of Ty transcription.
What is the protein family that this protein belongs to?
Belongs to the SPT2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COXX_AQUAE
Sequence: MSERVEAGQNVIKEYLVLTKPGIVSLVLITTLGGMYLGSRGELQPELVFWTLLGTGLAAAGSAVLNMVIDKDIDKLMVRTSERPLPKGTVDPTKAFIFGITLQVFSLVIMLTFVGVLPALLVALASFSYVILYSLLLKRKSPVATEIGGISGALPPVIGYVAASGSVDINAIALFLLMFMWQPPHFWVLALKYADDYKRAGIPTLPVARGVFITKLKTLLYTASLFPVSLIPYLTGLVENLYFVVAVVMNLIYLGLTLKFFFSKKEESMKLFFFSIIYLAVLFGTMIVDMVK
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QKI_FELCA
Sequence: MVGEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAVGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQLMELAILNGTYRDANIKSPALAFSLAATAQAAPRIITGPAPVLPPAALRTPTPAGPTIMPLIRQIQTAVMPNGTPHPTAAIVPPGPEAGLIYTPYEYPYTLAPATSILEYPIEPSGVLGAVATKVRRHDMRVHPYQRIVTADRAATGN
What is the function of this protein?
RNA-binding protein that plays a central role in myelinization.  Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence.  Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation.  Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation.  Participates in mRNA transport by regulating the nuclear export of MBP mRNA.  Also involved in regulation of mRNA splicing of MAG pre-mRNA.  Acts as a translational repressor (By similarity).
What are the official names of this protein?
KH domain-containing RNA-binding protein QKI, Protein quaking, FqkI.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.