PharMolix/UniProtQA huggingface dataset:
Protein: SCNNB_NEOFS
Sequence: MFLKRWFIRALHRLQKGPGYGYSELFVWYCNNTNTHGPKRLIIEGPKKKTLWSLFTVTFACLVFWQWGLLIQTYLSWGVSVSLSVGFRGMDFPAVTVCNVNPFKYSKVKPLLKELDELVDILLEQFYSYSTNGTLPVVFPDMRSSYLTGDPPPWYQIPLVMIDETDADNPTVTNVLGTDALSPTNNSTTNSSTEARRYKVAFHLCNTNGTDCFYKNFSSSLEAVKEWYTLQYIDIISKLPLSQKVEMGYSGKDFILTCLFGGEACNYDNFTQFYHSSYGNCYVFNWGLDGNVLIVSNPGVGFGLQLALDVNQEEYIPFLTTRAGARFLLHTQNTFPFVETMGTYALVGTVTSVGILVDEVQRMGQPYGTCTTDGLDVPIDNLYSQYNLSYTMQSCLWSCFQIQMVNSCGCAYYLYPLPEGATYCNNQNNSDWAYCYYLLQDSKDHKNECLQTCIQTCNELQFRISTSMADWPSESSEDWIFHVLSYERDDSTNITMKRDGVLKLNLYFKEFNYRVITESVATNVVWLLSNLGGQFGFWMGGSVLCIIEFGEVFIDCIWIAVIRFVKWYKNRKERQVQAQYADPPPTVSELVEGYTNQGFQPDIINSCSPQAQPPDLYLPTTLEIPGTPPPKYDSLRVHPIDTEHHSDSEDL
What is the function of this protein?
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride.  Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells.  Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.
What are the official names of this protein?
Amiloride-sensitive sodium channel subunit beta, Beta-NaCH, Epithelial Na(+) channel subunit beta, Beta-ENaC, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1B subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Note=Apical membrane of epithelial cells.
Protein: MET16_HUMAN
Sequence: MALSKSMHARNRYKDKPPDFAYLASKYPDFKQHVQINLNGRVSLNFKDPEAVRALTCTLLREDFGLSIDIPLERLIPTVPLRLNYIHWVEDLIGHQDSDKSTLRRGIDIGTGASCIYPLLGATLNGWYFLATEVDDMCFNYAKKNVEQNNLSDLIKVVKVPQKTLLMDALKEESEIIYDFCMCNPPFFANQLEAKGVNSRNPRRPPPSSVNTGGITEIMAEGGELEFVKRIIHDSLQLKKRLRWYSCMLGKKCSLAPLKEELRIQGVPKVTYTEFCQGRTMRWALAWSFYDDVTVPSPPSKRRKLEKPRKPITFVVLASVMKELSLKASPLRSETAEGIVVVTTWIEKILTDLKVQHKRVPCGKEEVSLFLTAIENSWIHLRRKKRERVRQLREVPRAPEDVIQALEEKKPTPKESGNSQELARGPQERTPCGPALREGEAAAVEGPCPSQESLSQEENPEPTEDERSEEKGGVEVLESCQGSSNGAQDQEASEQFGSPVAERGKRLPGVAGQYLFKCLINVKKEVDDALVEMHWVEGQNRDLMNQLCTYIRNQIFRLVAVN
What is the function of this protein?
RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts (PubMed:28525753, PubMed:30197299, PubMed:30197297, PubMed:33428944, PubMed:33930289).  Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs) (PubMed:28525753).  In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure (PubMed:28525753, PubMed:30197299, PubMed:30197297).  Plays a key role in S-adenosyl-L-methionine homeostasis by mediating N6-methylation of MAT2A mRNAs, altering splicing of MAT2A transcripts: in presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifically N6-methylates the first hairpin of MAT2A mRNA, preventing recognition of their 3'-splice site by U2AF1/U2AF35, thereby inhibiting splicing and protein production of S-adenosylmethionine synthase (PubMed:28525753, PubMed:33930289).  In S-adenosyl-L-methionine-limiting conditions, binds the 3'-UTR region of MAT2A mRNA but stalls due to the lack of a methyl donor, preventing N6-methylation and promoting expression of MAT2A (PubMed:28525753).  In addition to mRNAs, also able to mediate N6-methylation of U6 small nuclear RNA (U6 snRNA): specifically N6-methylates adenine in position 43 of U6 snRNAs (PubMed:28525753, PubMed:29051200, PubMed:32266935).  Also able to bind various lncRNAs, such as 7SK snRNA (7SK RNA) or 7SL RNA (PubMed:29051200).  Specifically binds the 3'-end of the MALAT1 long non-coding RNA (PubMed:27872311).
What are the official names of this protein?
RNA N6-adenosine-methyltransferase METTL16, Methyltransferase 10 domain-containing protein, Methyltransferase-like protein 16, N6-adenosine-methyltransferase METTL16, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
Protein: WHIA_MYCA9
Sequence: MAMTAEVKDELSRLVVTQVSSRRAEVASLLRFAGGLHIVSGRVVVEAEVDQGSIARRLRKDIFDLYGYNAVVHVLSAGGIRKTTRYVVRVAKDGEALARQTGLLDLRGRPVRGLPAQVVGGSVADAEAAWRGAFLAHGSLTEPGRSSALEVSCPGPEAALALVGAARRLGVSAKAREVRGSDRVVVRDGEAIGALLTRMGAQDTRLTWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERALEILGDTVPDHLAAAGKLRVEHRQASLEELGRLADPVMTKDAVAGRIRRLLSMADRKAKTEGIPDTESAVTPELLEEA
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RAPA_YERPB
Sequence: MPFTLGQRWISDTESELGLGTVVAIDVRMITLLFPATGENRLYARNDSPITRVMFNPSDTITHHEGWQLKVEEVTQENGLITYIGTRLDTEETGVAMREVLLDSKLTFSKPQDRLFAGQIDRMDRFALRFRARKYQSEQFRLPWSGLRGIRASLIPHQLHIAYEVGQRHAPRVLLADEVGLGKTIEAGMIIHQQLLAGRAERVLIVVPESLQHQWLVEMLRRFNLRFSLFDDSRYSEALLDSSNPFDTEQMVICSLDFVRRNKQRLEQLADASWDLLVVDEAHHLAWSEEAPSREYQVIEQLAEHIPGVLLLTATPEQLGQQSHFARLRLLDPDRFHDYEEFVNEQQKYRPIADAVTLLLGGERLTDDKLNLLGELIDEQDIEPLLKAANSQSEDSEAARQELVTMLMDRHGTSRVLFRNTRNGVKGFPHRVLHQIKLPLPTQYQTAIKVSGIMGAKKTLDARAKDMLYPEQIYQEFEGENATWWNFDPRVEWLLNYLVANRGEKVLVICAQAATALQLEQVLREREAIRAAVFHEGLSLIERDRAAAYFASEEDGAQVLLCSEIGSEGRNFQFACQLVMFDLPFNPDLLEQRIGRLDRIGQNREIQIMVPYLEDTAQAILVRWYHEGLDAFEHTCPTGRTIYDSSYQELISYLATPSEQEGLDEFIHTCRQQHEGLKLQLEQGRDRLLEMHSNGGEHGQELAQSIAEQDNDINLVSFALNLFDIVGINQEDRSDNLIVLTPSDHMLVPDFPGLPPDGCTVTFDREQALSREDAQFVSWEHPIIRNGLDLILSGDTGSCAVSLLKNKALPVGTLLAELVYVVEAQAPKHLQLTRFLPPTPVRMLMDRNGTNLAAQVEFESFNRQLNAVNRHTSSKLVNAVQQEVHTMLQQAEALVEAQAQALIETAKREADDKLSTELARLEALKAVNPNIRDDEIEALEHNRKMVLENLNQAGWRLDAIRLVVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: MSRB_ECOLC
Sequence: MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSETKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: NUSB_HELPJ
Sequence: MATRTQARGAVVELLYAFESGNEEIKKIASSMLEEKKIKNNQLAFALSLFNGVLEKINEIDALIEPHLKDWDFKRLGSMEKAILRLGAYEIGFTPTQNPIIINECIELGKLYAEPNTPKFLNAILDSLSKKLAQKPLI
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RS16_SYNP6
Sequence: MIKLRLKRFGKKREVSYRIVATNSTSRRDGLPLEELGFYNPRTNETRLDVPAIVRRLQQGAQPTETVRSILRKAQIFEQLKA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MAK5_MAGO7
Sequence: MTTDTTKQKRKLDSKQNTSPKRRKVQANGKAQPKAKKPKRVVAADSLSWRSVEIPELFDDAEGFFGLEEVEGVDVIRDGGMVKFVTAAPAAEKEDEGDDFSGFDDNPESTSLVAAEEAKSEEPAKPQSQKKQQTKQPKSETKEKKEKPAKAKKNEKQTSKTDDDDLATGSFAALAEIDETDEGADVSEWEPLGLSEEIMSSIAKLKFAKPTAIQAATIPEILAGHDVVGKASTGSGKTLAFGIPIVEKWLSINASTQSKRVAEGETKTPIALVLSPTRELAHQLTDHIKNLCAGLATSPYVCSVTGGLSVHKQQRQLEKADIVVGTPGRLWEVLSSSTKLIQAFRGIKFLVVDEADRLLSEGHFKDAKDIFEGLDKVETDDDGIIRGGKARQTLVFSATFNKGLQQKLAGKGRFDLATDSQSMEYLLKKLKFREEIPKFIDVNPVSQMAEGLKEGIVECGAMEKDLYLYSLLLMHPTQRTLVFTNSISSVRRLTPMLQQLTLPVIALHSQMIQKARLRSVERFTSSKPGSASILIATDVAARGLDIRGIDVVIHYHVPRTADAYVHRSGRTARADSSGLSILICAPEEVTPTRRLVAKVHASAAAKGKKKGSAGGVFVHSVELDRRLVSKLRERVQLAKQIADSTLAKEKIGKEDNWMQKAAEELGVEYDSEDLEKASNWSGRGSGRKSKQKEAKEMSKAEVASLKAQLKQLLSKRINSGVNERYIANGNVDIDGLLSGAKGDFLGKVEGLGVSPLLATD
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase MAK5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TRHO_STRP4
Sequence: MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFREXPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RPC1_HUMAN
Sequence: MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRMGTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQEEKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKCGLLKIIHEKYKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQENLNPLVVLNLFKRIPAEDVPLLLMNPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPGANFIQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARVKPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQNSELMSGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAGYKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALSKNELILTTESIMKKSEFLCCQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQVEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQLDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLLRLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYYVLQFLKEDLPKVVVQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGIEAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLASFEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKADRDPNPPKRPLIFDTNEFHIPLVT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.  Forms the polymerase active center together with the second largest subunit.  A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III.  A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity).  Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses.  Acts as nuclear and cytosolic DNA sensor involved in innate immune response.  Can sense non-self dsDNA that serves as template for transcription into dsRNA.  The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC1, RNA polymerase III subunit C1, DNA-directed RNA polymerase III largest subunit, DNA-directed RNA polymerase III subunit A, RNA polymerase III 155 kDa subunit, RPC155, RNA polymerase III subunit C160.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: METAS_CARH6
Sequence: MPLVAHRELESLDRLRAEGQEILDVRRASQQDIRELHIGLLNLMPDGALKATERQFLRLIGNSNRIAQFYVHIFTVPGVPRSADMQAYIDSHYENFDDLAHDGLDAIIFTGTNPLHADLAQEAYWPHVQRVFDWADKNVTSVLCSCLASHLALQHFHGIARKRRDEKLFGVFSHRVLDRSHPMLANINTRFDMPHSRWNGISAAQLEARGLPVLVAGEESGVAMASSPDGFRQIYFQGHPEYDRSSLLKEFRRDLALYQDGKLPQPPKLPTHYFTPAGQRLIRDYIESGRPISDFPEAQLADEVDVTWRDTAKALFANWLGLVYQLTHKERHLQYMDGIDPADPLGRLRR
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBK83_ARATH
Sequence: MAYLSFKSNMERTPRESNTPCPPPQPSPSLFSSLPDDIVLNILARISTSYYQTLSLVSKTFRLLILSKELDMERSYLGTRKPCVYVCLQSPTHPFDRRWFGLWIKPYDHQPLTHWTIDIKCTGHWLLPMPSPYSRCLQIVHETVGSETYEIGGQNMTPSTDVWVYDKLIGKQRKAPSMMVARKNAFTCVLDGKLYVMGGCEADESTHWAEVFDPKTQTWEALPDPGVELRYSSVKNIQTKQGKVYVRSNKKNFVYLIKECMWEVAEENLGESTCEIENVCYCYSNKRYWWYDAKCEEWRLVKGVSGLYEYYKTDSEIGNYGGKLVVFWDRAVSRLTATKEIWCAMISLEKGHDGEIWGHIEWLDAVLIAPRSYALSHCMDFLQ
What is the function of this protein?
Involved in seed germination.
What are the official names of this protein?
F-box/kelch-repeat protein At4g19330, Protein COLD TEMPERATURE GERMINATING 10.
Protein: ACYP_PYRIL
Sequence: MENVRAHLYIKGKVQGVFFRQSMKEIAVRYGVRGWVRNRSDGRTVEAVLEGPRDAVAKVIEWAKVGPPGARVEEVEVDWEEYKGEFQDFRILPTV
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RNP2_SULIK
Sequence: MNSIQLIIDIILILWLLILTVLYLRKKSLNLNIVKNKKIVRAKRYIVFYVIAESKVKGDDLERVVRNSLKDLLGNVWLNIANPKVVTYKEDTQEGIISTNRIGYKAVLASLPFAKEINGNKILIVPRRTTGSLKKAKKLIGLK
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_STAES
Sequence: MFDQLDIVEERYEQLNELLSDPDVVNDADKLRKYSKEQADLQKTVDVYRSYKTKKEELQDIEDMLNETSDKEEVEMLKEESSALKTELPDMEEELKILLIPKDPNDDKDVIVEIRAAAGGDEAAIFAGDLMRMYSKYAEANGFKTEIVEASESDHGGYKEVSFSVSGTGAYSKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEAEDVEIEIRNEDLKIDTYRSSGAGGQHVNTTDSAVRITHLPTGVIATSSEKSQIQNREKAMKVLKARLYDMKLQEEQQKYASQRKSAVGTGDRSERIRTYNYPQSRVTDHRIGLTLQKLNQIMEGNLDEIVEALTLSEQTEKLKELNNGEL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_CLOK1
Sequence: MKIRPLGDRVVIKKIEAEETTKSGIVLPGSAKEKPQEAEIVAVGPGGVIDGKEIKMEVKVGDRVLFSKYAGNEVKIDGVEYTILRQDDILAIIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_BURCH
Sequence: MTTLSPEAFAGHTPMMQQYLRIKADHPDTLVFYRMGDFYELFFEDAEKAARLLDLTLTQRGASAGTPIKMAGVPHHAVEQYLAKLVKMGESVAICEQIGDPATSKGPVERKVVRVVTPGTLTDAALLSDKNDVYLLAMCTGHNKRGVAVNIGLAWLNLASGALRLAEIEPDQLAAALERIRPAEILTPDGATDAIPAGAGASKRVPAWHFDIASGTQRLCDQLDVASLDGFGAHSLTSACGAAGALLLYAAATQGQQLRHVRSLKVENETEYIGLDPATRRNLELTETLRGTESPTLYSLLDTCCTTMGSRLLRHWLHHPPRASVAAQSRQQAIGALLDAPANASLDALRSALRQIADVERITGRLALLSARPRDLSSLRDTFAALPALRERIGAIVANADALARVDAALAPPAECLDLLTSAIAPEPAAMVRDGGVIARGYDAELDELRDISENCGQFLIDLEARERARTGIANLRVEYNKVHGFYIEVTRGQTDKVPDDYRRRQTLKNAERYITPELKTFEDKALSAQERALARERALYDSVLQALLPFIPECQRVASALAELDLLAAFAERARALDWVAPTFTDEIGIEIEQGRHPVVEAQVEQFIANDCRFGTERKLLLITGPNMGGKSTFMRQTALIALMAYVGSYVPAKSACFGPIDRIFTRIGAADDLAGGRSTFMVEMTEAAAILNDATPQSLVLMDEIGRGTSTFDGLALAWAIARHLLAHNACYTLFATHYFELTQLPAEFPQAANVHLSAVEHGHGIVFLHAVNEGPANQSYGLQVAQLAGVPAPVIRAARKHLAYLEQQSASQHTPQLDLFSAPPAAVDDLECADAPALPDTPHPALEKLRDIDPDDLKPREALDLLYELRTLVRSHDADGHA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: KDPB_THEVO
Sequence: MNQNIIYTVYGDLKLTLKNMRPDVLLHNPVMFLTEVSLFVSIFIYIFPSFFGVPYTGTYRSFYVAVVVLLFLTVFFSSISTALSEGKSKAITDSLKKFKTDVIAHVQKDGNIVDVRSNELKKNDIIIIYKDEIVPIDGEVIEGSGYVDESNVTGESRAVMKVIGDTVTGSTRLVTDKLKIRATADPGSTFIDKMIELVEKSTREKTPNEISLTVFLSGLTLIFLVITASIFAISHYFGRTANIVMLIVLLIALIPTTIGALLPAIGIAAINKVSEYNIIAKSGRAIENAGDIDTIILDKTGTITIGERKAVKFYPNKGISDVEFAKLAAMSSYYDQTKEGLSIFELAKKQGAEISKDDLKGYEFIPFSSETKFSGIQSPSDTVIKGSLKALKEKFQVADEFIEALCKEISMRGGTAIPVVHNGKFAGVIELQDLIKPGIKERISEIKNMDIKTVMCTGDDEVTAQYISAQAGIDEYIANSKPVDKYNVVIREKEGQRMVAMVGDGTNDAPALAKADVGLAMNNGTQAAKEAANMIDLDSNPTKLMDVIFLGKQILITRGSLTTFSIANDISKYFVIIPAIFYMFPSLSLVNILDLTDPIVAVTSALIFNTIIIVFLIPLALGGVHYKPTSISEMLKRNLMIYGIGGVITPFIAIKLIYMLLIAWGVTW
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMN_NOSP7
Sequence: MSATPLVSQVDSHNPEKSKLIPPLLGASVAELSAWVQQQGQPAYRGKQLHEWIYDKGVRSLADISVFSKQWRAEVAEIPIGRSTLHYRSVAPDGTVKYLLRLTDGQIIETVGIPTFAERGEGPKARLTVCVSTQVGCPMACDFCATGKGGYKRNLARHEIIDQVLTVQEDFQQRVSNVVFMGLGEPLLNTENVLAALKSLNQDIGIGQRSLTVSTVGIRDRIRQFAQNNLQITLAVSLHAPNQALREKLIPSARAYPLEELLAECREYVEITGRRVTFEYVLLAGVNDLPEHALELSKCMRGFQSHVNLIPYNPIQEVDYKRPNRDRIEAFVNVLKQQNTAVSVRYSRGLEADAACGQLRASKN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPS_BUCAI
Sequence: MQYKYLLEYNKKNHECNPCHVAIIMDGNGRWATRQGKIRIMGHKEGFRAVKEAIKFSIANNLKILTLYAFSSENWNRPLFEIKALMELFLFALDTEIKNLKKHNIRFKVIGDITCFDKKLQNSIHYAEQITFDNTGLILNIAANYGGRWDIIESVKKIINRVQRGILDVNKIHENTISQYLSTSELLPVDLVIRTGGEKRISNFLLWQIAYSELYFTDVLWPDFNCHIFQHAIDSFVSRERRFGGFKKNKK
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: SYP_PEDPA
Sequence: MKQSKILISTVKEVPNDAEVLSHKMMLRAGYIRQISAGMYAYLPLAYKVISKIEKIVREEMEAIDAVEMLTPAVLPAELWKQSGRYETYGQELYKFKNRHDRDFILGPTHEETMTTLIRDEVKSYKKLPLSLYQIQMKYRDEDRPRYGLLRGREFLMKDAYSFHADEETLDQSFRDFEKAYQNIFRRCGLNFREIVGDAGAMGGRDSKEFSAIASIGEDTIAYSEESDYAANLEMASSVYTDLQMHENQEELTKVATDDAHSIDEVAAKLDVDSNRLIKTMVLIVDEAPVLALLRGNDQLNEVKLTNLLHADEVREATEEEAFELLGAHVGSLGPVLENKPENLKIVADKYIEQMVNSVVGANEDGFHLKNVNVERDFTVDEYADIRTVREGELAPDGKGALKFTKGIEIGHIFKIGTKYSEALDAKVLDENGRAIPVIMGCYGIGVSRLLSAVSEQQSDENGLVWPKNIAPYDVHVIPVNAKNAEQMEIADQINGELTKAGYDVLVDDRKERAGVKFADSDLIGIPLRVTIGKKASEGIVEVKLRKTGEAVEVKVAELNNTVEILLNQAQ
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPG_ECOLC
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.