PharMolix/UniProtQA huggingface dataset:
Protein: ICMF_GEOKA
Sequence: MAHIYRPKHHVRFVTASSLFDGHDASINIMRRILQASGAEVIHLGHNRSVEEIVNAAIQEDVQGIAVSSYQGGHMEFFKYMYDLLQERGASHIRIYGGGGGVIIPREIKELHEYGIARIFSPEDGRRLGLQGMINVMLEECDFPTVTVVTDELERLPSGDVQAIARLITLCEYRAEGENKEAAAAAEAAIEQVKALEKRVPVLGITGTGGAGKSSLTDELVRRFLNEIPDIKIAILSVDPTKQKTGGALLGDRIRMNSINSPRVYMRSLATRHSRTELSPAIRDAISVVKAAGFDLVIIETSGIGQGDAAITEVCDVSMYVMTSEFGAPTQLEKIDMIDYADLIVINKFERKGSEDAKRQVQKQYQRSHQLFDRDVSEMPVYGTIASQFNDPGTNTLFVALVDTINKKAGTNWKTSLKTVANVEKHNVIIPNERRYYLREIAETVRSYHRRAEQQVEVARRLFQIEGAIEAAKERGEAEDVIRALETLKADYEAKLTPESKRILATWEETKAKYAAKQFVTKVRDKEIVTELTTKTLSGLDIPKVVLPKFKDYGEILRWVYKENVPGSFPYTAGVFPFKRQGEDPKRQFAGEGTPERTNRRFHYLCKEDKAKRLSTAFDSVTLYGEDPDYRPDIFGKVGESGVSVCTLDDMKKLYKGFDLCDPLTSVSMTINGPAPILLAMFMNTAIDQQVEKKEAELGRPLTPEEYEQVKEWTLQTVRGTVQADILKEDQGQNTCIFSTDFALKMMGDIQEYFIKHRVRNYYSVSISGYHIAEAGANPITQLAFTLANGFTYVEYYLSRGMHIDDFAPNLSFFFSNGLDPEYSVIGRVARRIWAIVMREKYGANERSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALLAIYDNCNSLHTNAYDEAITTPTEESVRRAMAIQLIITKEFGLTKNENPLQGSFIIEELTDLVEEAVLQEFERLNDRGGVLGAMEMQYQRGKIQDESLYYETKKHTGELPIIGVNTFLNPNPPSEDELNNIQLARATYEEKETQIRNLREFQERNKDKAGPALERLKQVATSGGNIFEELMETVKVASLGQITRALYEVGGQYRRNM
What is the function of this protein?
Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, and to a lesser extent, of pivalyl-CoA and isovaleryl-CoA, using radical chemistry.  Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.  Also displays ATPase activity.  Is not able to convert 3-hydroxybutyryl-CoA to 2-hydroxyisobutyryl-CoA.  Does not exhibit methylmalonyl-CoA mutase (MCM) activity.
What are the official names of this protein?
Fused isobutyryl-CoA mutase.
What is the protein family that this protein belongs to?
Belongs to the IcmF family.
Protein: ATPL_VIBCM
Sequence: METVLSFSAIAVAIIVGLCAVGTAIGFAVLGGKFLEGAARQPEMAPMLQVKMFIIAGLLDAVPMIGIVIALLFTFANPFVGQLAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NANE_VIBCM
Sequence: MRPVVRKNFLNIEELKRFLNGQTVVSIQPVTGSPLDKTDFIVAMAIAVEQAGAKALRIEGVNNVAAVSAAVTIPIIGIVKRDLPDSPIRITPFVSDVDGLANAGATVIAFDATDRTRPESRERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIVGSTLSGYVGDIEPTVPDFQLVKAFSEAGFFTMAEGRYNTPELAAKAIESGAVAVTVGSALTRLEVVTQWFNNATQAAGERKCAH
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: GPMA_STRAW
Sequence: MADAPYKLILLRHGESEWNAKNLFTGWVDVNLNEKGEKEAVRGGELLKDAGLLPDVVHTSLQKRAIRTAQLALESADRHWIPVHRSWRLNERHYGALQGKDKAQTLAEFGEEQFMLWRRSYDTPPPPLADGSEFSQSDDPRYASIPPELRPKTECLKDVVNRMLPYWYDGIVPDLLTGRTVLVAAHGNSLRALVKHLDGISDEDIAGLNIPTGIPLSYELDTDFKPLNPGGTYLDPDAAAAAIEAVKNQGKKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: GATL6_ARATH
Sequence: MLWITRFAGLFSAAMAVIVLSPSLQSFPPAAAIRSSPSPIFRKAPAVFNNGDECLSSGGVCNPSLVHVAITLDVEYLRGSIAAVNSILQHSVCPESVFFHFIAVSEETNLLESLVRSVFPRLKFNIYDFAPETVRGLISSSVRQALEQPLNYARSYLADLLEPCVNRVIYLDSDLVVVDDIAKLWKTSLGSRIIGAPEYCHANFTKYFTGGFWSEERFSGTFRGRKPCYFNTGVMVIDLKKWRRGGYTKRIEKWMEIQRRERIYELGSLPPFLLVFSGHVAPISHRWNQHGLGGDNVRGSCRDLHPGPVSLLHWSGSGKPWIRLDSKRPCPLDALWTPYDLYRHSH
What is the function of this protein?
May be involved in pectin and/or xylans biosynthesis in cell walls.
What are the official names of this protein?
Probable galacturonosyltransferase-like 6, Like glycosyl transferase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: SYP_AZOSB
Sequence: MRARQFFISTLKEAPADAEVVSQKLMLRAGMIRKVAAGIYNYLPMGLKSIRKVENIIREEMNRAGALELTMPLVQPSELWQETGRWDKMGPEMLRFKDRHERDFALQPTSEEVVTDIARQELKSYRQLPKNFYQIQTKFRDERRPRFGVMRGREFTMKDAYSFDRSAEAAGESYDAMYAAYSRIFDRLGLTYRAVAADTGAIGGDRSHEFQVIADTGEDAIVYCPDSSYAANIELAEALSLLPARAGASAPLAKTPTPGKSTCEDVAALLGVPLASTVKSLVLATDDEDESGKVVKSTVWLLLVRGDHELNEVKAGKIEGLKAGFRFATEAEILDHFGCKPGYLGPIGLAQPVKVIADRTVANMADFVCGANAEDFHYTGANWGRDLPEPDLVADIRNVVEGDPSPDGKGKLAIQRGIEVGHVFYLGTKYSKAMNATFLDVDGKPKHFEMGCYGIGVTRILGAAIEQNHDERGIIWPASIAPFEVVICPVGWSKSEAVRDEAQKLYDALVAAGVDVILDDRDERPGVMFADWELIGVPHRVTIGDRGLKEGVAEYQGRRDPEASRVAVAEIAPHLISRLRP
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6B1_AGRT9
Sequence: MTVANWQVRDLTLILRTGEMKSRLEQARTDFGALLSETVYFQPSAIRLGEFDDEYIHSRQELVYVYLREDIARQCALRRNLPSNSSNFGTMATAIPPWLMNARSLNRVMQERCDQGGLVNYYQGPHTNQFFLAIMPSNCFVRFGTDIINNENYGFXARRGNTLEEGEDDDDEMDDEGEAGGAEPRECQIGNLINYPIIALGSCDLSA
What is the function of this protein?
Involved in tumor formation and increases auxin and cytokinin effects in host plants.
What are the official names of this protein?
Protein 6b.
Protein: FN3KR_ORYSJ
Sequence: MANVALLSAASPSTSSAAPRLRHVARRRPSRRSACPRSAASRLSIMAALGEDPIRQWILTEGKATKITGVSSIGGGCINSAQCYKTDASSFFVKTNGRIGPSMFEGEALGLKAMYDTNSIRVPLPYKVGSLPTGGSFIIMEFIEFGCSRGDQSALGRKLAEMHKAAKSDKGYGFYVDNTIGSTPQINTWTADWIEFYSKHRLGFQLELITQRFGDSAIYDKGQRLIENMHPLFEGAVMEPCLLHGDLWSGNISSDTNGEPVILDPACYYGHNEAEFGMSWCAGFGGEFYSSYFEVMPKQPGFEKRRDLYLLYHYLNHYNLFGSGYRSSAMSIIDDYLRMLKA
What is the function of this protein?
Initiates a process leading to the deglycation of proteins.  Phosphorylates low-molecular-mass and protein-bound erythrulosamines and ribulosamines, but not fructosamines or psicosamines, on the third carbon of the sugar moiety.  Protein-bound erythrulosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions.
What are the official names of this protein?
Protein-ribulosamine 3-kinase, chloroplastic, Fructosamine 3-kinase-related protein.
What is the protein family that this protein belongs to?
Belongs to the fructosamine kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NIKR_SHIB3
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: MSCL_MYCBT
Sequence: MLKGFKEFLARGNIVDLAVAVVIGTAFTALVTKFTDSIITPLINRIGVNAQSDVGILRIGIGGGQTIDLNVLLSAAINFFLIAFAVYFLVVLPYNTLRKKGEVEQPGDTQVVLLTEIRDLLAQTNGDSPGRHGGRGTPSPTDGPLASTESQ
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RKM5_YEAS1
Sequence: MAFKLWLLDEETIYEHVFERYTQLEGQSGKLAQDLGIQDRRGGVLEITFEPSGLEGGRKKKRVRRRNKASSVEEDQNVAVDSYHVSVGQSISSLHSSRDNGNSTTGYVLWSTTPFFINWLLYSTSAAPFRLGSQVEVTCGSSCEGHKLELPRLVDLTGADRGKRGILELGAGISGILPVILGNFVDTYVSTDQKGILNKLKDNIMENLSQLTRKRCISRSLRLELPTVEPVGDADITAASLPSKSTLHLEVAALDWEKINLQDKKTHSLHPELSLIGETCSSVYVIAMDVIYNEYLIDPFLKTLKQLKHWLQTTYNLQFHVLVGIHLRSQEVTTLFLEKAIIEYDFTVYDIVDQVIQESRFNFYLIT
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L1 (RPL1A and RPL1B) at 'Lys-46'.
What are the official names of this protein?
Ribosomal lysine N-methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RKM5 family.
Protein: SESD1_MOUSE
Sequence: MEASVILPILKKKLAFLSGGKDRRSGLILTIPLCLEQTSMDELSVTLDYLLSIPSEKCKARGFTVIVDGRKSQWNVVKTVVLMLQNVVPAEVSLVCVVKPDEFWDKKVTHFCFWKEKDRLGFEVILVSANKLTRYIEPCQLTEDFGGSLTYDHMDWLNKRLVFEKFTKESTSLLDELALINNGSDKGNEQEKERSVDLNFLPSVDPETVLQTGHELLSELQQRRFNGSDGGVSWSPMDDELLAQPQVMKLLDSLREQYTRYQEVCRQRSKRTQLEEIQQKVMQVVNWLEGPGSEQLRAQWGIGDSIRASQALQQKHEEIESQHSEWFAVYVELNQQIAALLNAGDEEDLVELKSLQQQLSDVCYRQASQLEFRQNLLQAALEFHGVAQDLSQQLDGLLGMLCVDVAPADGASIQQTLKLLEEKLKSVDVGLQGLREKGQGLLDQISNQASWAYGKDVTIENKENVDHIQGVMEDMQLRKQRCEDMVDVRRLKMLQMVQLFKCEEDASQAVEWLSELLDALLKTHIRLGDDAQETKVLLEKHRKFVDVAQSTYDYGRQLLQATVVLCQSLRCTSRSSGDTLPRLNRVWKQFTVASEERVHRLEMAIAFHSNAEKILQDCPEEPEAMNDEEQFEEIEAIGKSLLDRLTIPVVYPDGTEQYFGSPSDMASTAEHIRDRMKLVSLKRQQLRHPELVTTES
What is the function of this protein?
May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5.  Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol.  The binding to PIP2s is calcium dependent.  Might be involved in the plasma membrane localization of CTNNB1 (By similarity).
What are the official names of this protein?
SEC14 domain and spectrin repeat-containing protein 1, Huntingtin-interacting protein-like protein.
What is the protein family that this protein belongs to?
Belongs to the SOLO family.
Protein: METK_MAGSA
Sequence: MSKKNFLFTSESVSEGHPDKVADRISDAVVDAFLGADPYARVAVETLVTTNLIVMAGEVRGPASVNAALMDELARHAVKDIGYEQDGFHWKNAEIINRVHSQSADIAQGVDAAGDKDEGAGDQGIMFGYACNETPVLMPAPIYYSHEILKSLAEARHSGAAPQLLPDSKSQVTLEYRDGKPVRATSVVVSHQHVDGLSQADIKEIVRPHVKNVLPEGWMPAEDQFYVNPTGRFVIGGPDGDTGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNVVASGLADKCVIQLSYAIGVSKPLSVYVDTSGTCKVDEDKLAVVLQQLVDLSPRGIRTHLGLNKPIYARTAAYGHFGRSPDADGGFSWEKTDLVEQLKKAF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMDH_GIBF5
Sequence: MAAILLPQRFRGEAPVTEKTTPSWASKRLTPIAQFLSRLACSHPIHTVVVVAVLASTSYVGLLQESLFNTDVESATLGKADWSTLVEGSRVLRAGPETAWNWKAVEQDVVADAGSDADHLALLTLVFPDSLSAESSSTAPRSHHVPIPQNLSITSLPSTENPFTAYSQDSILAYALPYSEGPEFLAAAQEIPNEDAVEIETKHGREKKTWIMKAAKVNTRNSVVQWVSNAWSEFLDLLKNAETLDIVIMLLGYIAMHLTFVSLFLSMRKMGSKFWLGICTLFSSVFAFLFGLVVTTKLGVPISVILLSEGLPFLVVTIGFEKNIVLTRAVMSHAIEHRRIQAQNSKSGKRSPERSTQNMIQYAVQAAIKEKGFEIIRDYAIEIVILVIGAASGVQGGLQQFCFLAAWTLFFDFILLFTFYTAILSIKLEINRIKRHVDMRMALEDDGVSRRVAENVAKGDDELNRVRGDAPLFGRKSSSIPKFKVLMILGFIFVNIVNICSIPFRNPSSMSTIRTWASSLGGVIAPLSVDPFKVASNGLDAILATAKSNNRPTLVTVLTPIKYELEYPSIHYALGSAASNPAYNDAFHHHFQGYGVGGRMVGGILKSLEDPVLSKWIVIALALSVALNGYLFNVARWGIKDPNVPEHNIDRNELARAQQFNDTGSATLPLGEYVPPTPMRTQPSTPAITDDEAEGLHMTKARPANLPNRSNEELEKLLSEKRVREMTDEEVISLSMRGKIPGYALEKTLGDFTRAVKIRRSIIARNKATTDITHSLDRSKLPYENYNWERVFGACCENVIGYMPLPVGVAGPLVIDGQSYFIPMATTEGVLVASASRGCKAINSGGGAITVLTADGMTRGPCVAFETLERAGAAKLWLDSEAGQDMMKKAFNSTSRFARLQSMKTALAGTNLYIRFKTTTGDAMGMNMISKGVEHALSVMANDGGFDDMQIISVSGNYCTDKKAAALNWIDGRGKGVVAEAIIPGEVVRSVLKSDVDSLVELNVAKNLIGSAMAGSVGGFNAHAANIVAAIFLATGQDPAQVVESANCITIMKNLNGALQISVSMPSLEVGTLGGGTILEPQGAMLDILGVRGSHPTNPGDNARRLARIIGAAVLAGELSLCSALAAGHLVRAHMQHNRSAAPSRSTTPAPPMTPVSLAMTSAQERSASTTSMSAAAIQRSKR
What is the function of this protein?
HMG-CoA reductase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (By similarity).  In this module, the cytosolic acetyl-CoA acetyltransferase catalyzes the formation of acetoacetyl-CoA (By similarity).  The hydroxymethylglutaryl-CoA synthase then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA (By similarity).  The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase HMGR (By similarity).
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NAPA_ECO8A
Sequence: MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLLRMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAASKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAEMHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYIIQNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVAEYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPGGTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVSDPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFSRRFKTEEVWPEELLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFYLQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGEGYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRAFPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAAQLVNKLTLDATDPLSKETDFKKCAVKLEKV
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: CRTN_STAAN
Sequence: MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDLAELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAKLKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIKGGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTADFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDDFRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSDEALTQQIKEIIYRKLATIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLAQSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIERGV
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes three successive dehydrogenation reactions that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene as intermediates, and 4,4'-diaponeurosporene (the major deep-yellow pigment in staphylococci strains) as the end product.
What are the official names of this protein?
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming), Dehydrosqualene desaturase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtN subfamily.
Protein: RL17_POLNS
Sequence: MRHGNGLRKLNRTSSHRLAMLRNMSNSLLEHEVIKTTLPKAKELRMVVEPLITLGKKDNLANRRLAFNRTRDRDFVTKLFTELGPRYATRPGGYLRILKFGFRHGDNAPMALVELVDRPEVEETAAVAEEA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DNAJ_LACCB
Sequence: MADQKDYYETLGVSRDADDDTIRKAFRKLSKKYHPDLNHAPGAEQKFKDINEAYQVLSDPQKRAAYDQYGSADGPQGFGGAGAGQGGFSDFGGGQGGFGGFDDIFSQFFGGAGGGAQANPSAPRQGADLQYRMDLTFEEAIFGKDTKISYDREAVCHTCNGSGAKPGTSPVTCHKCHGSGYIQVQRNTAFGAMMTRQVCDVCGGTGKEIKEKCPTCHGTGHEQERHTIDVKVPAGVEDGQQMRLQQAGEAGTNGGPYGDLYIVFRVAPSKKYQRDGSEIYLTIPLSFAQAALGDEIKVDTVHGAVELKIPAGTQSQTKFRLRGKGAPRLRGNGTGDQIVTVEVQTPKHLNEKQKSALMQFAAASGEDVTPHNGTLFDRVKEAFKGGK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB28_SYNJA
Sequence: MATIEFSPGIPEVPTQVRLLKSKTGKRGSAIFRFEELKSDTQSILGMRMIDEEGELTTRNIKAKFLNGEFKALEVIYDMETEAEWERFLRFMERFSAANQMGMA
What are the official names of this protein?
Photosystem II reaction center Psb28 protein, Photosystem II 13 kDa protein, Photosystem II reaction center W protein.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YAAA_SALHS
Sequence: MLILISPAKTLDYQSPLATTRYTQPELLDHSQQLIQQARQLSAPQISRLMGISDKLADLNATRFHDWQPHFTPDNARQAILAFKGDVYTGLQAETFNDADFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENPRGKDLYQFWGDIITDKLNEALEAQGDRVVVNLASEEYFKSVKPKKLNAELIKPVFLDEKNGKFKVVSFYAKKARGLMSRFIIENRLTKPEQLTAFDREGYFFDEETSTQDELVFKRYEQ
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: EFG_ORITI
Sequence: MSENHKLSYVRNIGIGAHIDAGKTTTTERILYYTGVSYSIGEVHDGTTVMDYMKQERDRGITIQSAATTCHWIKKDDCAEQASQKEQEYKINIIDTPGHVDFTIEVGRALRVLDGMIAVFDGVAGVEPQSETVWRQADKYAVPRICFVNKMDRMGADFFRCVQMMKDRLGTKPLVIQLPIGIEDTFKGVIDLVKMKAIVWSNEDLGAKYEYHSIPNNMQAMVEDYRHQLLETVVEVDEEIFNSYVSNEDLSEEDIRKCIRKGAISGLFVPVLCGSAFKNKGVQTLLDAVVDYLPSPNDVNSIKAVDVKTEQEISRKVSVDEQFSALAFKVINDPFVGSLTFIRIYSGKLQTGSTVINTTKNQKERISRMLLMHANNRKDIKEAVAGDIVALTGLKSTTTGDTICSLDSQIILEKIEFPKPVIELAVEPKTPADQEKISAALVKLAAEDPSLVFTVDSETNQMVIKGMGELHLEIIIDRMKEEFKVEANVGAPRVAYRETITQSYTVDYTHKKQTGGAGQFARVKIIFEPLEAGAGFQFESKIVGGAIPKEFIPGVEKGLEEIKESGVVAGYPTIDFKATLIDGSFHEVDSSVLAFEIAAKNAFKEGITKAGPKLLGPIMKVEVISPNEYMGDIIGDLNSRSGVIQSMEPRGNTQIINAYVPLGQMFGYVSTLRSLSQGRAQYSMVFSHYEQVSRSIAEKIQAKDKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPDE1_MYCS2
Sequence: MIEVQEFRAEVRQWLADNLVGDFAALKGLGGPGREHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYARANAPDKVNHFGEELLGPTLIEYGTPEQQKRFLPKILDVTELWCQGYSEPNAGSDLANVSTTAELVGDAEASGATGNQYWVINGQKVWTSLAHWAQWCFVVARTEKGSKRHAGLSYLLVPLDQPGVEIRPINQLTGDSEFNEVFFDDARTEAGLVVGQPGDGWRVAMGTLTFERGVSTLGQQIRYAREHSNLVELAKRTGAADDPLIRERLVQSWTGLQAMRSYALATMDVEQPGQDNVSKLLWANWHRELGEIAMDVQGMAGLTLENGEFDEWQRLYLFSRADTIYGGSNEIQRNIIAERVLGLPREVKG
What is the function of this protein?
Involved in cholesterol degradation.  Catalyzes the dehydrogenation of 5OH-HIP-CoA to 5OH-HIPE-CoA.
What are the official names of this protein?
Acyl-CoA dehydrogenase IpdE1, 5OH-HIP-CoA dehydrogenase alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: APDR_EMENI
Sequence: MHVDSRGNAPVRRRRPAVACTECRRRKIRCDQATPCRHCEKAALRCIYNHLRPNTSQSKISPPTSASGFISGSQLSVNDSPQLPLSNDTKFHGFGSGSLKSDLSLEYVPSALPTSSSIFVEPNSLSSLSEPLAWEIAPPETGVGILAESDSPLNMQGQTGELRDQHTAPWMEILHCDPDEFWFDSEELRRMWRKTRDLELLLATSKMPSEWLYWSPGPTAPEASSLIPPRATCDVLLELQYWSSPDSMSDVFLCKLLLAMAIGTLFAPASPSAGQLTDMRPRALAWMHYGQQWLFRKIVLDAQLNLDILQTSPTSIGDRHFWLSEDCLVRMAMKLGLHRDPHIHNPAMLGTEVEVRRRLWVTLLELSLQASLDAKLPVPLPSDGGFDTELPSNLSDTDLGSIATLCNPNPRTFFTHSTMQILLAETQRIRIRILNLLYSPATSIPYQEALKLASELRRACNTNLRLLQSFTPQTPGAMMPTEFQTKILDLWTRRFLLALLTPYADEARSDYSLYYTRKARIDASSLLLSYPLSHSTATGPSPIGSYYLQLQISGQGIFRNVLKQATAAICQDLIQELVEDAFPVTDREPHAKLCQIIRDSISIYRTRMELSQPCMQEYVAFVCASAQIGALRSRCDNKHDFFPTAKKALGQCHHILESNHRSNSPEKYRAETMHVLDIDQGMNFWSDLLSTAGASPLSPPSSSSFFLEHGLSHTVPWEAPHSREVVDNER
What is the function of this protein?
Transcription factor involved in regulation of gene cluster that mediates the biosynthesis of aspyridones (PubMed:17369821).
What are the official names of this protein?
Aspyridones cluster regulator apdR, Aspyridones biosynthesis protein R.
What are the subcellular locations of this protein?
Nucleus.