PharMolix/UniProtQA huggingface dataset:
Protein: CODY_STRS7
Sequence: MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIFPVESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLNLQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_ACAM1
Sequence: MTDAVSTTTLLKDRDRLEARLKEIPPEPGVYFMRDANDDILYIGKSKKLRNRVRSYFRQIQDHPPRIELMVHQVADIEFIVTDTEAEALALEANLIKQHQPHFNVLLKDDKKYPYLCVTWSQTYPRIFITRKRRLGKAQDKYYGPYVDVWQLRQTLRLVKRLFPLRQRRKPLFKDRPCLNYEIGRCPGVCQALITPEAYRQILQKVVMIFQGRTSELINTLSLQMEQAAEDLNFEQAARLRDQIKGLQGLGVDQKVALPDDTVSRDAIALAADDQIACVQLFQIRSGRLVGRLGFMADAQSGSLGMILQHVLEAHYGSAEPVELPLEILVQTELPETELLASYLSQRKERKVSITCPQRQIKAELIEMVERNAQYELARTQKSRDRTLNALQDLAELLDLPELPHRIECYDISHIQGSDAVASQVVFIDGLPAKQHYRRYKIRNPNVKAGHSDDFASLAEVLHRRFRQYHLSPEQPRQGTSDWPDLVVIDGGKGQLSAVLESLTKIEVVEDLQIISLAKQREEIFQPGESQPLPTDPEQPGVQLIRRLRDEAHRFAISFHRKKRLERMRRSRLDDIPGLGHHRQKELLAAFRSIDYIREASPEQLKAVPTIGPQLAQKIYDYFHPA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_RICBR
Sequence: MFITSLKNQKEFELINKLGKKFHEKYFILVIAKNIPKIFLESKYNIFLGIKVSKKLNKKAVVRNKIKRRIKHLIRLICNNSNLKKLAMIIIPRKGFDTADFSVLNHELSKAILDFYNPKK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: KAD_ACET2
Sequence: MRLVLLGAPGAGKGTQAVVISQKYNVPHISTGDIFRSNIKNGTELGRKAKEYIDKGLLVPDELTVDIVKDRISQPDCKAGFILDGFPRTIYQAERLDEILKELNVELDCALNIYVPDEEIIKRMSGRRVCSKCGMSYHIVYNQPKVENICDSCNGELIQRDDDKEETVIQRLNTYHKQTEPLIEYYEKKGKLLTVHGQEGVDDTTKEVLNALSGVKL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_PROM3
Sequence: MVLPASMRLRGSRCFERLQKWGYRFYGTSMVLRVIEADPQLLKAPHRHHNSTACRCAVVISSKVSKRAVIRNRLRRRLHNHLRSRLEVAPEHCNHWVLISLKPVASAIEASPLLEECDRLLHQAGLLS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RPOA_ALKOO
Sequence: MIEIEMEKPKVEVVEINAENTYGKFTVEPLERGYGTTLGNSLRRIMLSSLPGAAVTSVKIDGVLHEFSTIPGVKEDVAEIIINLKGLSIRMHGNEPKTVRIEAKGEGVITAGDIIADADVEILSPDTHIATLDTDAVLNMELTIAKGRGYVPAENNKTPGMPIGVLPIDSIFTPVTKVSYHVENTRVGQVTDYDKLVIEVFTDGSIVPDEAISLAAKIMNEHLNLFITLTDHVNDVEIMVQKEEDKKEKVLEMTIEELDLSVRSYNCLKRAGINTVDELAQKSEEDMMKVRNLGRKSLEEVQKKLEELGLGLRPSDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: C617_CONCL
Sequence: MSGTGVLLLTLLLLVTMATSDDACSLLNGDDCGPGELCCTPSGDHQGTCETSCW
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Cal6.17, O3_cl6d.
What are the subcellular locations of this protein?
Secreted.
Protein: SUB2_ARTGP
Sequence: MQFLSLNLLLLLPFVAGDLAPQPEPLRAGPSDVVPGQYIVTLKEGLSSAQIRDHKKWVNSVHRANLDSFAAGASGVETEGIMKHFHIHNLNMYSGGFDEKTAEELSRNPYVKSVHPDQHVYLAKTVTQPQARWGLGYMSSKGKPVPLHSTLVDYLYDDKAGEGVWAYVLDTGINVNHVEFEGRGILGHNAIPNKPHTDEFGHGTYVAGIIAGKTYGVAKKANVVSAKAFDTGSSTYNYILETYDWIVRNITDSNRKNKAVINLSISGAKYQPFDDAVENAFKAGITTVVAAGNDGKDAKNNTPASSPNAITVGAVRWENTRPSFSNYGKIVDIWAPGELIKSCWKGSNTATSTQSGTSAASPHVAGLVAYLMSFENLPSPSAVTARVLNLTIPNLVKDAKDSPNRVVYNGIQERKFTLPKDY
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF1_SHISS
Sequence: MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_MAGMA
Sequence: MSPKTETKASVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLASQGNEIIREASKWSPELAAACEVWKEIKFEFKAVDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: I17RB_MOUSE
Sequence: MLLVLLILAASCRSALPREPTIQCGSETGPSPEWMVQHTLTPGDLRDLQVELVKTSVAAEEFSILMNISWILRADASIRLLKATKICVSGKNNMNSYSCVRCNYTEAFQSQTRPSGGKWTFSYVGFPVELSTLYLISAHNIPNANMNEDSPSLSVNFTSPGCLNHVMKYKKQCTEAGSLWDPDITACKKNEKMVEVNFTTNPLGNRYTILIQRDTTLGFSRVLENKLMRTSVAIPVTEESEGAVVQLTPYLHTCGNDCIRREGTVVLCSETSAPIPPDDNRRMLGGWLPLFLVLLVAVWVLAAGIYLTWRQGRSTKTSFPISTMLLPLIKVLVVYPSEICFHHTVCRFTDFLQNYCRSEVILEKWQKKKIAEMGPVQWLTTQKQAADKVVFLLPSDVPTLCDSACGHNEGSARENSQDLFPLAFNLFCSDFSSQTHLHKYLVVYLGGADLKGDYNALSVCPQYHLMKDATAFHTELLKATQSMSVKKRSQACHDSCSPL
What is the function of this protein?
Receptor for the pro-inflammatory cytokines IL17B and IL17E.  May play a role in controlling the growth and/or differentiation of hematopoietic cells.
What are the official names of this protein?
Interleukin-17 receptor B, IL-17 receptor B, IL-17RB, IL-17 receptor homolog 1, IL-17ER, IL-17Rh1, IL17Rh1, Interleukin-17B receptor, IL-17B receptor.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: NADE_BACMK
Sequence: MTLQEQIMKALHVQPVIDPKVEIRKRIDFLKDYLKTTGAKGFVLGISGGQDSTLAGRLAQLAVAEVRNEGGNATFISVRLPYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYENLLDESLTDFNKGNVKARIRMVTQYAIGGQQGLLVIGTDHAAEAVTGFFTKFGDGGADLLPLTGLTKRQGRDLLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKSVPADVAEKIEKRYKVSEHKRQVPASMFDDWWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: OTCC_PHOPR
Sequence: MAFNLRNRNFLKLLDFTPREIQHMLELAAELKKAKYNGYEQPRLKGKNIALIFEKASTRTRCAFEVAAYDQGANVTYLGPSGSQIGYKESMKDTARVLGRMYDGIEYRGFGQEIVETLGAHAGVPVWNGLTDEFHPTQILADFLTMQEHARGKQLSEVTFAYLGDARNNMGNSLMVGAAKMGMDIRLVAPKAFWPEEELVAQCREIAEETGAKITVTEDVQEGVEGCDFLYTDVWVSMGEAKEAWAERISLMMPYQVNMAMLKATGNPHVKFMHCLPAFHGEDTVVGKELAQEYPELKDGVEVTDEVVESKHSIVFDEAENRLHTIKAIMVATLGQ
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_RHILW
Sequence: MLKFTEEHEWLQIEGSVATVGITNYAVDQLGDLVFVELPEVGATFSKNGNAATVESVKAASDVYCPLDGEITEVNPAIVADPSLVNSDPQGAGWFFKLKLANPADADGLLDEAAYKELTA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: SEC11_CANTT
Sequence: MNLRQQITQFLTLAYVFSSAFMLWKTLSVIANSHSPIVVVLSGSMEPAFQRGDILFLWNRENRQKVGDIVVYEIDGKSIPIVHRVLREHHNNEKQLLLTKGDNNAVDDLSLYAKKQQYLNQKEDLVGTVKGYLPFIGYVTILISENVYFKYGMLGLLGLSALFSNE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: GSA_SALTI
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAELVTNLVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLTSVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGIHETLDELTTRLAEGLLEAAEEANIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHLMLEEGVYLAPSAFEAGFMSVAHSMDDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYL4_PIG
Sequence: MPPKKPEPKKEAAKAAPAPAPAPAPAPAPPPEPAKEPTFDPKSIKIDFTADQIEEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNAKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQEDANGCINYEAFVKHIMSG
What is the function of this protein?
Regulatory light chain of myosin.  Does not bind calcium.
What are the official names of this protein?
Myosin light chain 4, Myosin essential light chain, atrial isoform.
Protein: SYA_CAMJE
Sequence: MDIRKAYLDFFASKGHEITPSSPLVPDDATLLFTNAGMVPFKSIFTGEIPRPNPPRKTSCQTCIRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEQAIAYAWEFVTEVLKLPKDRLYVTVHENDDEAFNLWQKHIQKERIYKFGDKDNFWQMGDTGPCGPCSEIFYDQGQEHFNSSEDYMGGDGDRFLEIWNLVFMQYERSADGVLSPLPKPSIDTGMGLERVTAIKEGKFSNFDSSLFMPIINEISKLCNKTYVYESGASFRVIADHIRSSVFLLAQGVSFDKEGRGYVLRRILRRALRHGYLLGFKQAFMYKLVDVVCDLMGGHYTYLNEKKDFIKEQIRLEEERFLSTIENGIEIFNEELKNTKEIFSGEVAFKLYDTYGFPLDLTADMLREKNLKVDEEKFELFMNEQKARAKASWKGSGDKTASGDFKNLLEKFGENHFVGYEKAECESKILALLDEDFKEVSTLKDAGWVMLENTPFYATSGGQSADSGFIAKREVLDTQKFFNLNLSFIKAGEELKVNDIVHARIDTEKREQIARHHSATHLLHHALREILGSHVSQAGSLVESNKLRFDFTHHKALNKEELESIEKRVNKMIINSSEAILENMPLEEAKKSGAIALFNEKYQGNVRVLTLGESKELCGGTHVKNTAQIGSFYIVKESGVSAGVRRIEAVVSKAALEFVKNQLEELSKVKDELKNNDILSGIKKLKNEILSLKNELKNSSKTELDSKNIQGVEICVKRIDNGDIKAMIDDFKNKFAKAVILLIQVKDEKITLAAGVKDVPLKAGALVKEAAQILGGNGGGRDDFATAGGKDLSKINEALKQSLETIEKAL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APGM_METTP
Sequence: MKYVVLLGDGMADWPMEALGGRTPLQVARKPNMDSIARIGRCGLARTVPEGMTPGSDVANLSIMGYDPRRYYTGRAPLEAAAMRIPLGEKEVAFRCNFVTVMDGIMDDYSAGHITSEEGAEIAESLKKVIPGGRIYPGVSYRNIVVLKVCRDAVCTPPHDIMGKPISDHLPRGDDAHILIDIMERARPLLEEHPVNRRRVSMGLKPANMIWLWGQGPAPSMPRFHEIYGLKGAVISAVDLLKGLGVCAGWRVIDVPGATGTIDTNYAGKVRAALEALGSVDLVYLHIEAPDEAAHSGDVEQKIRAIELFDERVVGPMIHGLERSGEAWRVLLLPDHPTPIEIRTHSTDPVPFAIAGSGVCVDSVDAFDEISASEGGYGMIEGNDLIRLLIAG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: H2AXA_ORYSI
Sequence: MSSSQGGGGRGKAKTTKAVSRSSKAGLQFPVGRIARYLKAGKYAERVGAGAPVYLSAVLEYLAAEVLELAGNAARDNKKNRIVPRHIQLAVRNDEELSRLLGTVTIAAGGVLPNIQQVLLPKKGGGKGDIGSASQEF
What is the function of this protein?
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation (By similarity).
What are the official names of this protein?
Probable histone H2AXa.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YORQ_BACSU
Sequence: MFKKGQKVIVDFTDEIGAVAKVDYRYNQIEVKYPDGTYQVVGFHKVRKVED
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YorQ.
Protein: ISPDF_HELPH
Sequence: MSLIRVNGEAFKFSLESLEEDPFETKETLEILVKQTSVVLLAAGESRRFSQTIKKQWLRSNHTPLWLSVYESFKEALDFKEIVLVVSELDYIYIQRHYPEIKLIKGGASRQESVRNALKIIDSAYTLTSDVARGLANMETLKSLFLTLQQTSHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKTLQSALNQGDFKDESSAILQAFPNSVSYIEGSKDLHKLTTSDDLKHFAFFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAVLGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYKQKL
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: G3P_THEKO
Sequence: MKVKVGINGYGTIGKRVAYAVSKQDDMELIGVTKTKPDFEAYLARERGIPVYAASEEFLPRFEKAGFEVAGTLSDLLENVDVIVDATPGGMGAKNKALYEKAGVKAIFQGGEKAEVAQVSFVAQANYEKALGKDYVRVVSCNTTGLTRTLSALQEYIDYVYAVMIRRAADPNDSKRGPVNAITPSVTVPSHHGPDVQTVIPINIETMAFVVPTTLMHVHSVMIELKKPITREDVIDIFENTTRVLLFEKERGFESTAQLIEFARDLHREWNNLYEIAVWKESISVKGNRLFYIQAVHQESDVVPENVDAIRAMFEMADKWESIRKTNKSLGILK
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_BRUA2
Sequence: MTTELHDDASGRLIVGLDVPTIAEAEKVVEELGNAVSFYKIGYQLVFAGGLDFAKSLVAARKKVFLDMKLLDIDNTIAKGVENVAKMGVSMLTLHAYPKAMRAAVEAARGSDLCLLGVTVLTSMDNADLREAGYFDNAETLVLKRARQAHEAGMGGIVASAVEAQAIRQAVRPDMAIVTPGIRPAGSEKGDQKRVMTPADALRAGASHLIVARPIVGAPDRKAAALAILKEMRSIGRS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: DEOC_PYRAE
Sequence: MIHLVDYALLKPYLTVDEAVAGARKAEELGVAAYCVNPIYAPVVRPLLRKVKLCVVADFPFGALPTASRIALVSRLAEVADEIDVVAPIGLVKSRRWAEVRRDLISVVGAAGGRVVKVITEEPYLRDEERYTLYDIIAEAGAHFIKSSTGFAEEAYAARQGNPVHSTPERAAAIARYIKEKGYRLGVKMAGGIRTREQAKAIVDAIGWGEDPARVRLGTSTPEALL
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP61_PHOPR
Sequence: MAAPGEALTSSSYITHHLTNLAVGDGGFWTVHIDSLFFSVLTGLAFILVFHSVAKKATSGVPSKLQCFVEMLVEFVDNSVKETFHGRNPLIAPLGLTIFCWIMLMNIMDLIPIDFIPYAAEHALGIPYLKIVPTADVNITMAMALGVFALMLYYSVKVKGLGGFAKELALHPFNHPIMIPFNLLLEVVSLIAKPISLGMRLFGNMFAGEVVFILIAALMPWWAQWLGSVPWAIFHILIITIQAFVFMMLTIVYLAQAHEDNH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 1, ATP synthase F0 sector subunit a 1, F-ATPase subunit 6 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y3394_BACC7
Sequence: MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAGVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSAGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINEIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDHHAS
What are the official names of this protein?
UPF0316 protein BCAH187_A3394.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL22_STRS7
Sequence: MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTPNKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: NRDR_CLOBJ
Sequence: MKCPYCAYGESKVVDSRSTEDGSSIRRRRECLKCNRRYTTYEKIETTPILVIKKNMSREYFDRNKIVNGLMKACQKRPVSRKQIEQIANEVERHISNEMLTEVNTDKIGQIIMKNLKKIDEVSYVRFASVYRQFKDINTFMEEIKNLMDKN
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.