PharMolix/UniProtQA huggingface dataset:
Protein: PQSB_PSEAE
Sequence: MLIQAVGVNLPPSYVCLEGPLGGERPRAQGDEMLMQRLLPAVREALDEAAVKPEEIDLIVGLALSPDHLIENRDIMAPKIGHPLQKVLGANRAHVFDLTDSSLARALYVVDTLASDQGYRNVLVVRGESSQGLEVDSESGFALADGALALLCRPTGKAAFRRGALGGDPAQEWLPLSIPLNTDIRQVGDVKGHLNLPAQPGLPEAVRAGFTRLAGDFPQLNWVREEWFGQGRPDGRCLGPFELASQLRAAQRDRLDELLLISFDPFGMVVEGVTLELAGEAHA
What is the function of this protein?
Required for the biosynthesis of the quorum-sensing signaling molecules 2-heptyl-4(1H)-quinolone (HHQ) and 2-heptyl-3-hydroxy-4(1H)-quinolone (Pseudomonas quinolone signal or PQS), which are important for biofilm formation and virulence.  The PqsC/PqsB complex catalyzes the condensation of 2-aminobenzoylacetate (2-ABA) and octanoyl-CoA to form HHQ.  PqsB, together with PqsC, catalyzes the coupling of 2-ABA with the octanoate group, leading to decarboxylation and dehydration, and resulting in closure of the quinoline ring.  PqsB is probably required for the proper folding of PqsC rather than for a direct enzymatic role in the process.
What are the official names of this protein?
2-heptyl-4(1H)-quinolone synthase subunit PqsB.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGA_PSEPK
Sequence: MPDYVNWLRHASPYINAHRDCTFVVMLPGDGVEHPNFGNIVHDLVLLHSLGVRLVLVHGSRPQIESRLADRGLTPHYHRGMRITDAATLDCVIDAVGALRLAIEARLSMDIAASPMQGSRLRVASGNLVTARPIGVLEGVDYHHTGEVRRVDRKGISRLLDERSIVLLSPLGYSPTGEIFNLACEDVATRAAIELGADKLLLFGAEPGLLDADGRLVRELRPQQVAPHLQRLGSDYQGELLDAAAEACKGGVARSHIVSYAEDGALLTELFTRGGGGTLVSQEQFEVVREATIEDVGGLLELISPLEEQGILVRRSREVLEREIEQFSVVEREGMIIACAALYPIADSEAGELACLAVNPEYRHGGRGDELLERIESRARQMGLSTLFVLTTRTAHWFRERGFAPSGVERLPAARASLYNYQRNSKIFEKPL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GOGA5_ORYSJ
Sequence: MASWLKVAEDLLEVVDRRAKIVATELSDEQSSPQPSGSSSQEGQAKKGKLREKGPLKLATGDAGSRTAAQKERKSRQPPRERIKIEKIRPSPPVDSSSVDASASKPDVSSSDVKGLDDDGGAEKEEKVVVDRKNDIGAEVVDTEVEVQSTERSAEDAAIVVDGAADSGNSEGAAESSAPSVPDERCEPSISNQDAEIVSAVNLEEKDSAMEVIHEKNIKEVPDTQVSGKSQDSKREGLSDSPESTENQQEHKLDSGSVKDQDQLEEARGLLKNVVKTGQSKEARLARVCAGLSSRLQEYKSENAQLEELLVQEREKCSSYEAHMKQLQQELSMSRVEGSRAESNMVDALTAKNAEIESLVKSLDSWKKKAAASEEKLAALQEDMDGLKRNRELTETRVIQALREELATVERRAEEERIAHNATKMAAVEREVELEHRAVEASNALARIQRAADQSSSRAMELEHKVAVLEVECASLQQELQEMEARNRRAQKKPSEEANQVIQMQAWQEEVERARQSQREAETKISSLEAELQKMRVEMAGMKRDAEHYSRQEHVELEKRYRELTDLLYHKQTQLESMASEKAALEFQLEKSIKQFHEVQMEAERSRVARRSASAWEEDADIKALEPLPLHHRHMATANQQLQKAAKLLDSGAVRATRFLWRHPVARVSLLFYLVFVHLFLMYLMHRLQDFASREGPTAMGGLANSDLP
What is the function of this protein?
May be involved in maintaining Golgi structure and in intra-Golgi transport.
What are the official names of this protein?
Golgin-84.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PURA_YERPN
Sequence: MGKNVVVLGTQWGDEGKGKVVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVISIIGNGVVLAPDALMKEMTELEARGVPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVSDLFNKETFAIKLKEIVEYHNFQLVHYYKEAAVDYQKVLDDVLAIADILTAMVVDVSELLDNARKQGELIMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGIVKAYSTRVGAGPFPTELNDETGEFLRKQGNEYGATTGRSRRTGWLDIVAVRRAVQINSLSGFCMTKLDVLDGLKEVKLCVGYRMPDGREVDTTPLAAEGWEGIEPIYETMPGWSETTFGVKEHSKLPQAALNYIQRVEELTGVPIDIISTGPDRDETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_PSESM
Sequence: MLSIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYDLTYVRNITDIDDKIINRARDNGESFDALTARMIDAMHEDEARLNILKPDMEPRATDHIPGMHAMIQTLIDKGYAYAPGNGDVYYRVGKFQGYGKLSRKKIEDLRIGARIEVDESKQDPLDFVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGDTFDIHGGGSDLEFPHHENEIAQSEAATGKPYANAWLHCGMIRINGEKMSKSLNNFFTLRDVLEKYHPEVVRYLLVSSHYRSAINYSEDSLRESKAALERFYHALKGLPAAEPAGGEAFVERFTTAMNDDFGTPEACAVLFEMVREINRLRETDVAAAAGLAARLKQLASVLGVLQLEADDFLRAGAQGRVDAAEVEALIQARLAARAAKDWAESDRIRDQITAMGVLLEDGKGGTTWRLGD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUB_DELAC
Sequence: MNRPSLAGAVHLHGFSRSFHGKQVLDDLGLDIAPGQFVALLGESGSGKTTLLRALAGLDVEARSSGTAVAHGNVSVLFQDSRLLPWLTVLDNLTLGLDAQAVRPAAAQLLREVGLADKAAAWPASLSGGQKQRAALARSLLREPHVLLADEPFGALDALTRLRMQGLLRRMVERVRPTVILVTHDVDESLLLADRILVLRDGKIAEDHALDLAHPRRPDHPAFMQLRATLLRSLGVEAEFV
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CDC6_ORYSJ
Sequence: MPTLRSATASASTAGTASPTAIATPRSAKRRLTSPRRAAGSPDASQFTSPHKSPNVGIVGTPKLLSASPRSSRKRLYGDFVAAEKPKWNPRGKSPESHFSRAQSSDWDLTKEFICSADPAQMQVVKEALHVATVPSCGLVCRDDEQSRVLEFCKGCVEQERSGSLYVCGCPGTGKTLSINKVKESVARWADETGMETPDALSINCTSLAKTHEIFSKILAKFQTRKKATCKLSPLQQLQTMFSHKESAPRRMLLVVVDEMDYLITRDRAVLHDLFMLTTYQFSRCILIGIANAIDLADRFLPKLESLNCKPLVVTFRAYSKDQISDIIKHRLKVLEYDVFEPLALEFCARKVAAASGDMRKALGVCRSAVEVFEARLQESSDQEFGLVTFDHMDIALSKAFKSPVVDSILCLPQHQQMVLCALANTFHHCKKKATTLGELNKSYIEICRSTQVPAVGMLEFSNMCMVLSDQGFMKLGQSKEDKLRRVMLQIDSSDITFAFKGNRFFQKCLEQQKF
What is the function of this protein?
May be involved in the initiation of DNA replication.
What are the official names of this protein?
Cell division control protein 6 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SMT1_DICDI
Sequence: MNTQQRAMEGDLSRIVAISRKEKDAVSRNDKVDDTLNGYKELFKGNDDKAIQARKNNYTHMVNTFYDLATDFYEFGWGQSFHFATRHKYESFEASIARHEMYMAHQLGLFPGMKVIDIGCGVGGPMRTIARFSGANVVGLNNNEYQIQRGKRLNESAGLSHLCSFIKADFMHVPVEDNTYDCAYQIEATCHAPDLVGLYKEVFRIVKPGGLFGGYEWIMTNKFNPEDPVEVNIKKQIELGNGLPDLVKPAEIINAAKAAGFEVITAFDVAETSELPWYLPLSSGVSITGFLHTGVGRYLTGKFTQLLEIVKLAPAGSYNTNVWLQNAATFLVQGGEKQIFSPMFFLLCRKPSTD
What is the function of this protein?
Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of cycloartenol to form 24-methylene cycloartenol.
What are the official names of this protein?
Probable cycloartenol-C-24-methyltransferase 1, 24-sterol C-methyltransferase 1, Sterol 24-C-methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
Protein: ZAPD_ECOUT
Sequence: MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFFRNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVLISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIASLNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGHKSRFAIRFMPLDSENGQVPERLDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: GLYA_PLAF7
Sequence: MFNNDPLQKYDKELFDLLEKEKNRQIETINLIASENLTNTAVRECLGDRISNKYSEGYPHKRYYGGNDYVDKIEELCYKRALEAFNVSEEEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHLCSGGHLTHGFFDEKKKVSITSDLFESKLYKCNSEGYVDMESVRNLALSFQPKVIICGYTSYPRDIDYKGFREICDEVNAYLFADISHISSFVACNLLNNPFTYADVVTTTTHKILRGPRSALIFFNKKRNPGIDQKINSSVFPSFQGGPHNNKIAAVACQLKEVNTPFFKEYTKQVLLNSKALAECLLKRNLDLVTNGTDNHLIVVDLRKYNITGSKLQETCNAINIALNKNTIPSDVDCVSPSGIRIGTPALTTRGCKEKDMEFIADMLLKAILLTDELQQKYGKKLVDFKKGLVNNPKIDELKKEVVQWAKNLPFA
What is the function of this protein?
Catalyzes the interconversion of serine to glycine accompanied with the production of 5,10-methylenetetrahydrofolate, a source of one-carbon units used by thymidylate synthase to convert dUMP to dTMP for DNA synthesis (PubMed:11071283, PubMed:19591883, PubMed:24914963).  Binds to its own mRNA and to the mRNA of bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) in vitro; the physiological relevance of this interaction is not clear (PubMed:19591883).
What are the official names of this protein?
Serine hydroxymethyltransferase, PfSHMTc.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion matrix. Plastid, apicoplast. Nucleus. Note=Predominantly localizes to the cytoplasm in early trophozoites and postmitotic schizonts. Transiently localizes to the mitochondrion and the apicoplast in late trophozoites and in mitotic schizonts. Partially localizes to the nucleus, especially in late trophozoites and in mitotic schizonts.
Protein: UVRB_STAAM
Sequence: MTMVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORDA_ASPFA
Sequence: MIYSIIICAGALLGLWILEKLLAPKDTRPPLPPGPWRKPIIGNLSDFPPKGTPEWLFWAKHQERYGPMSSLEVMGQTIIMINDAQLGIEIMHKKSALSQMIPDAPFAHMAGWGMSLATERNRQAWKTIRANMKQEIGTRRAISTFHPKMEIGIRRFLLRTLDNPDDLRFHIRKEANAFMMDVAYGYTIAPHGKDELYDLTQQSVRQFSHIFSPGEWSVNFFPILRYVPSWFPGASFQIKAAEYKRTIERMTMVPYLWIKDQVARGCSRPSILLRLLQKGHYESGSHQEQVLVWTNAEFVMGGSDTTVSAVSSFFVAMALYPEVQRKAREELDRVVGPTTLATFEHRLQLPFIDALVKEVFRWHPASPLGAPHITQEDQIWDGYLLPKGALLLPNIWTFTHDPSVYHDPMVFKPERFLEGKDSPPETDPMKFVFGFGRRICPGRFVTDEKLFLIACHAVSCFFISPKDPGAPEPDWLPGVISQPGAFDLNVVPRSPAHEELIRSIETDHPWKNADATDISRFMARNQMI
What is the function of this protein?
Converts O-methylsterigmatocystin (OMST) to aflatoxin B1 and converts dihydro-O-methylsterigmatocystin (DHOMST) to aflatoxin B2 in the aflatoxin biosynthesis pathway.
What are the official names of this protein?
O-methylsterigmatocystin oxidoreductase, OMST oxidoreductase, Aflatoxin B synthase, Aflatoxin biosynthesis protein Q, Cytochrome P450 64.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: SYP_BURL3
Sequence: MKASRFFIGTLKEAPADAEIVSHKLMVRAGMIRRVAGGIYNYLPVGLRSIRKVEAIVREEMNRAGGIELLMPAVQPAELWQESGRWEQYGPELLRFKDRKDNDFVIGPTHEEVITDIARNQIKSYRQMPVNFYQIQTKFRDEIRPRFGVMRGREFIMKDAYSFDKDAAGLNESYRKMYDAYVRIFTRLGLEFRAVAADSGSIGGNFSHEFHVIADTGEDAIAYCPTSEFAANIEAAEALPLIAERAAPAEAMEKVATPGKAKCEAVAELLAIPLERTIKSIVLATDNEGAEPTIWLVMLRGDHDLNEIKVSKLPGLKNHRFATEQEIVEWFGTPPGYLGPVGTKKPVKVIADRTVANMSDFVVGANEVDYHIAGVNWGRDLPEPDVADVRNVKKGDPSPDGKGVIDICRGIEVGHVFQLGTKYSEAMGATFLDESGKPQPMLMGCYGVGVTRILGAAIEQNFDDKGIIWPESIAPFEVVLCPMGYDRSDMVRETADKLYAELVAAGIDVILDDRGERPGVMFADWELIGVPHRLVIGERGLKEGKIEYQGRRDAEATLLPADAAAATVAEKIRAALAR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPMA_ECODH
Sequence: MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: PSBF_IPOWR
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TRF5_ASHGO
Sequence: MMTASVAGNRSGRSGNIARERSNRSRGAQKSDKERNLSKGSSRPKSNSSRVKKMRKSSLSKVQKNFAVFNDSAEHENKYETLAVAEADEKEVILLDEEEDTAMTTETKGVHAEETANVTGAEGVNAAANALDDNQDFIGFSDSEEEVASGEENGDADYAVEDAEDESSEPLPTNADYPWIQNHDHSRQREIADWLTLEIKDFVSYISPNKTEIQLRNDALKRIRDAVQDFWPDANLHCFGSYATDLYLPGSDIDCVVNSKSGDKDNKNALYSLASYLKRNGLATQVSVIAKARVPIIKFVEPASQIHIDLSFERTNGVEAAKIIRGWLHDTPGLRELVLIVKQFLHARRLNDVHIGGLGGFSIICLAYSFLKLHPRIICRDIEPLQNLGVLLIDFFELYGKNFGYDDVGIAVSEGDASYINKKEYPELTRNLRGTFNLVIQDPGDPANNISRGSFNIRDIKKAFAGAFELLTNRCFELDAATFKHRVGKSILGNVIKYRGAKRDFKDERALIVNKAIQENEEFHQRRGRIVHRDTAEFINISDDDDYELQPPPKRARVPAPAPAPADNVVVLDDPADDYVPAQPVDKLMGLDDTDDYLPAPASPTDTPKLDKAAKRNYWLSKGQTM
What is the function of this protein?
Catalytic subunit of the TRAMP5 complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information.  Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates like cryptic transcripts generated by RNA polymerase II and III, or hypomethylated pre-tRNAi-Met.  Polyadenylates RNA processing and degradation intermediates of snRNAs, snoRNAs and mRNAs that accumulate in strains lacking a functional exosome.  TRF5 is also required for proper nuclear division in mitosis and sister chromatid cohesion.  Involved in the regulation of histone mRNA levels.  May mediate mitotic chromosome condensation (By similarity).
What are the official names of this protein?
Poly(A) RNA polymerase protein 1, Topoisomerase 1-related protein TRF5.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LIPA_BORA1
Sequence: MSTQLDASQPSNDVASPAAYDPTQKQKSQAKTARIPIKVIPAERLKKPEWIRVRAAAPGSRFYDIKRILREHNLHTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDAQEPENLARTIAALKLSYVVITSVDRDDLRDGGAAHFVECITKIRELSPITRIEVLVPDFRGRLDRALAILNAGPPDVMNHNLETVPRLYKQARPGSDYLHSLKLLAEFKALHPDVPTKSGLMLGLGETDEEILEVMRDMRAHNVDMITIGQYLQPSEHHLPVLRYVHPDTFAMFEREAYAMGFSHAAVGAMVRSSYHADEQAHAAGVN
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_DESHD
Sequence: MAGTFTLRVVSPEGNVLKEEAEFVVLPGGNGEIGILPNHAPLISSIEIGVIRYTVNGKVEKIATSGGFVEVSDNKVTILADTAEPGERVDLDRALAAKERAEKRLTQREGIDVRRAELALMRAVARINAARN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ISPD_ALKOO
Sequence: MENISKTSVIIVAAGKGKRMGRDYNKQYIQLEAQPIVAHTIKVFEEMDCINEIILVVGAGEVEFLKKSIIEVYGFQKVSAIVEGGLERRDSVYNGLKAVSQDCSIVLIHDGARPLITKDIIEESIIVAKESGACIAAVPVKDTIKISNDNMEVIHTPKRDNLWSVQTPQTFQYDLILEAYNHQQPKDSTATDDAMILEALGHTVKIIHGSYNNIKITTPEDLIVAEEILKTRREGR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: NIT2_BOVIN
Sequence: MATFRLALIQLQVSSIKSENLTRACGLIREASKQGAQIVSLPECFNSPYGTKYFPDYAEKIPGDSTQKLSEVAKECSMYVIGGSIPEKDAGKLYNTCAVFGPDGTLLVKHRKLHLFDIDVPGKITFQESETLSPGDSFSLFDTPYCRVGLGICYDIRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQRGRAVDNQVYVATASPARDEKASYVAWGHSTVVNPWGEVLAKAGTEETIVYADIDLKKLAEIRQQIPIFSQKRSDLYEVEAKKS
What is the function of this protein?
Has omega-amidase activity.  The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively.
What are the official names of this protein?
Omega-amidase NIT2, Nitrilase homolog 2.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKG1_ADEG1
Sequence: MSTQIPARQETYDPSQSSGTKTPSHPYDGNPTRSYPKRNAGKFTTYSSQMIAPRKRKAWEYEEEEYEASRDFYQRVTSWYDGAVDLAPQLFREQHFPSYDEFYSLGGVNEKFLEAHEEVKAQEQMDSRYLQHGQLPSINMGKQPIIGVIYGPTGSGKSHLLRALISCNMLDPIPETVIFITPEKNMIPPIEQTSWNLQLVEANFDCREDGTIAPKTSTFRPEFMEMTYEEATAPEHLNIDHPDNIYVKVSKRGPVAIIMDECMDKLCSGSSVSVLFHALPSKLFARSAHCTAFYIFVVLHNMAPRTAIGNVPTLKVNAKMHILSCHIPQFQFARFLYAFAHNISKDLVVLLKAYFSFLQQNQRFSWVMYTPDPVSESFRWCSIDQQYSIIPLNVNIQERFLKTAKSIIKFSETHRKQLERNPKLTDLEKLSPPGTFQET
What is the function of this protein?
Component of the packaging machinery which encapsidates the viral DNA into preformed capsids and transcriptional activator of the viral major late promoter (MLP).  Binds, along with packaging proteins 2 and 3, to the specific packaging sequence on the left end of viral genomic DNA and displays ATPase activity thereby providing the power stroke of the packaging machinery.  The activity of packaging protein IVa2 is stimulated by protein 33K which acts as a terminase.  May be the protein that pumps DNA into the capsid powered by ATP hydrolysis.  Specifically binds to the 5'-CG-3' nucleotides of the repeats making up the packaging sequence.  Component of the DEF-A and DEF-B transcription factors that bind downstream elements of the major late promoter (MLP), and stimulate transcription from the MLP after initiation of viral DNA replication.  DEF-A is a heterodimer packaging proteins 1 and 2 and DEF-B is a homodimer of packaging protein 1.
What are the official names of this protein?
Packaging protein 1, Packaging protein IVa2.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae packaging protein 1 family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleoplasm. Host nucleus, host nucleolus. Note=Located at a unique vertex of the capsid. Present in about 6-8 copies per virion.
Protein: YACL_ECO81
Sequence: MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEDAARTLKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: CALM_DANRE
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
What is the function of this protein?
Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding.  Calcium-binding is required for the activation of calmodulin.  Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: SSPK_BACCR
Sequence: MGKQAEFWSESKNNSKIDGQPKAKSRFASKRPNGTINTHPQERMRAANQQEE
What are the official names of this protein?
Small, acid-soluble spore protein K, SASP K.
What is the protein family that this protein belongs to?
Belongs to the SspK family.
What are the subcellular locations of this protein?
Spore core.