PharMolix/UniProtQA huggingface dataset:
Protein: EIBE_ECOLX
Sequence: MSKKFTMTLLSSSLAGLLVMSGGVSAQEEKYTVPYAIGEGKWGNTYEVVKTGGNGNFRYEVKEKNGKKRSLFTFDSKGDVIINGSGITYTIHDGALNDFAQTAEKKKNGQSQSHRMTDSVVRDVYNKVYSLQRTKITGFSVEDGENGKVSLGSDAKASGEFSVAVGNGAKATEKASTSVGSWSAALGRQSVALGVGTYAYANASTAAGTAAYVDGSAIYGTAIGNYAKVDKNATEGVALGAKAISAHKNSVALGANSRTTRDNEVYIGYEEASGKAYKTRTLGGLTDGTRPSDAATVRQVDRVKDSVEQLAQDTNTRLVVEAKKSREYTDSRTTVGVNPDGKLTRAEGATKTIAVNDGLVALSGRTDRIDYAVGSVDRRVTKNTQAIQSNTRQLQEHNARLNSQQRQIRENHEEMKRAAAQSAALAGLFQPYSVGKFNATAALGGYSDKQAVAVGVGYRFNEQTAAKAGIAASDGDVSYNMGVNFEF
What is the function of this protein?
Binds (in a non-immune fashion) to the Fc portion of human IgG and very weakly to IgA; binding occurs on the cell surface.  Confers the ability to survive exposure to human serum exposure.
What are the official names of this protein?
Immunoglobulin-binding protein EibE, Trimeric autotransporter adhesin EibE, TAA EibE, Type 5 secretion system autotransporter EibE.
What is the protein family that this protein belongs to?
Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family. Eib subfamily.
What are the subcellular locations of this protein?
Cell surface. Cell outer membrane. Note=The C-terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface.
Protein: Y1624_HAEIN
Sequence: MELKKIAVGLTALLGMSVANAHNVWLEPASSQDEYVVKFGHEQTETYPESKLKSIQALNSQGKLTAVDYQFRNGEAYLMPKSDLVFVHFDNGVWSKLPSGKYVEKTKREEPTAEFSTNPVKFGKAILKWDAESFKSHQQAYELIPQEKAQANKPLSILVLHNGKPVQGIKVGVSEDAPFNLTNEKGIAQFTPTKGFNKVWAEFEEKVTNNADYDRRTVEYMLTFDAQ
What are the official names of this protein?
Uncharacterized protein HI_1624.
Protein: PROA_HAEIG
Sequence: MLEQMGKQAKDAAFILAQLTTAEKNCALSIIAEQLEQQAPLILAENAKDIELAKQNGLSDALIDRLLLTQERLQGIANDVRHVISLADPVGKIIDGGTLDSGLKIERVRTPLGVIGTIYEARPNVTIDVASLCLKTGNAVILRGGKETQFSNKILIEVVQNALEQAGLPKFAVQAITDPNRELVMQLLKLDRYVDMIIPRGGAGLHELCKQHSTIPVIVGGVGVCHIFVEKSADQNKAVFVIDNAKTQRPSTCNTLETLLVQHSIAEEFLPKLVSHLSAKNVKYHAKSTALNILKQAGANVCEVTEKELRKEWGSLDLNVVVVEDIHAAIEHIRQYGTQHSESILTSSQNLARQFINQVDAAAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTSYKWVCEGEYTVRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y386_DESPS
Sequence: MKSSLAVLSTARSDTTTTYIGRNQMIAPMAFQAKRSTFLCPLLVALAILFSLTAVSSGTSWAKDHAGSSQATVSAVAGDNQAVTAKGEVKNSFAPIKTCFNFLKEQPFVFILLALAIGYPLGKISLWGISLGPTAGTLLVGVLISIIGQNIFGIIYGIPSIVSTIFLLMFMYALGLKVGPQFFSGLKTGGLAFIVIGLIVWSLNWLICFFGVKLAGLEAGFAPGIISGSYTITAIIGVAQTALTNGAYTPPPGVSTEQIGANIAAGYAISYVLSNIGIILLIRYLPQIFGHDPIADAQLAEKELSGGATDPVPGAAGSLSLGFSHFDLRAYEVDHQEIIGKTVQEFFHLYPEAPILRVVRQGKLLNLSENNPIKRGDIVSVRADVHELIADGKKLIGKESDSILARDVPIEVADIHIGSRDVAGDTLAELGRSIGFGLQLKALFRFGQELPLLAGTAVQVGDVLRFVGPDFCIQQAAKRLGGRPILNSSITEVMYMAIAMGIGYIFGSLSFNFAGIPFALGTSAGCLLAGIFMSYWRSRNPEFGGPMSEGARSFLQDIGLNLFVAVLAAAVGPKIIESFHGTTAIWVAIIGILGALVPPLVAFVVGIKVFKLNSVVAAGASTGARNSTPGLNAICEQSQSAVAAVPYPLTYALTTVLALVGGYFAMLLS
What are the official names of this protein?
Uncharacterized transporter DP0386.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYR_PYRFU
Sequence: MMETIKSEIKRTIEGIVREMAPDWSEDIQFVDTPSPELGDFGTPVAFQLARLLRKSPLIIAQEIAEKFNKNKPKEVKKAIAVNGYVNFFLDYPQISKLVIEAILGYGTEYGRSEIGKGKKVIVEHTSVNPTKPLHMGHARNAILGDTVARILRFLGYQVEVQNYIDDLGVQFAQVYWGYLNLKRKFDELMKELKEKIPKNNPIDHVLGLLYVEVNKKIEESSEVEKEIRELMKKLEERELNGRKLAEEVVKAQMETLYSLNIYYDLLVWESDIVSTRLFEKTIKLLEKNENFYTPKEGKYKGAFVMDLSKLFPDMKNPYLVLRRSDGTATYTGKDIAYHLWKFGKIDIDLMYKKWDEHTWTTAPDGEPIPGKFGAGDIVINVIGAEQRHPQLAIKYALELLGYKDAAENFHHLAYEHVESPEGKFSGRKGTWVGFTVDEVIAEAINKAKSLIEEKNPNLTEEEKEEIAKKVAVGAIRYTLIKYSPEKKIVFRWEDVLNFEGESAPYIQYAHARCSSILRKAEELGISTDWKSLLKVANFNQITEKERELIMLLSRFPEIVQQAGTDLKPHLIAWYANEVASTFNKFYMDHPVIKAEEGVREARLLLVMATRQVLRNSLWLMGIEAPDKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_RICBR
Sequence: MNNTYYITTPIYYVNDVPHIGHAYTSVASDVIARFMRLSGHEVMFLTGTDEHGQKVEKAAIDKNIDPQKFTDQTSQSFRHLMTAMHISNDDFIRTTEERHKKAVAIFWQKLLDNGSIYEGFYEGWYAVRDEAFYDESELTADKLAPTGAAVEWVKEPSYFFNLSKWQDKLLEFYEANPDFIRPISRRNEVISFVKSGLKDLSVSRTTFNWGIKVPNDNKHVIYVWLDALANYISALGYPDQNSNYGKFWPANLQVVGKDILRFHAVYWPAFLMAAEIPLPKTIMAHGWWTNEGQKISKSLGNTIDPIKLIEEFGVDQVRYFLMREITFGADGNFARSNLITRINSELSNKIGNLLQRTTSFVYKNNDGKVPAITQDAINKIYELPLLKTAINSAKQNILLMEKTEINKILDNIINLAEEANIYIDSEAPWNLKKTDPEKMLEVLYALLETLRYIAVMLQAFMPSSAGKMLDQLGVNTEERLFKHLSLEFALTSASDILEPVIVFPRFEE
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR2_DELRA
Sequence: GQDFMRF
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
FMRFamide-like neuropeptide GQDFMRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NFUA_MANSM
Sequence: MQQIQISDAAQGHFRKLLDQQEEGTNIRIFVVNPGTPNAECGVSYCPPNAVEATDTEMKYATFSAFVDEVSLPFLEDAEIDYVTEELGTQLTLKAPNAKMRKVADDAPLIERVDYVIQTQINPQLASHGGRITLVEITDEGYAILQFGGGCNGCSMVDVTLKDGVEKQLVELFAGELKGAKDITEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: TSAC_COLP3
Sequence: MSEKNVVEAFKNGGIIAYPTEAVFGLGCDPDNKEALKRLLKLKQRSPEKGLILLAGSYSQLLPYIDDSKIPQDKRLTLLSRWPDGITQLVPKNNNISSLLSGSFDTIAVRITSQPDVVALCQQTNKPIVSTSANLSGQEPAKTWQSLDLVLSKQVDFILKGVTLGRTSPSKIIDALTGKIIRN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_STAAR
Sequence: MATKNEEILRKPDWLKIKLNTNENYTGLKKMMREKNLNTVCEEAKCPNIHECWGARRTATFMILGAVCTRACRFCAVKTGLPNELDLNEPERVAESVELMNLKHVVITAVARDDLRDAGSNVYAETVRKVRERNPFTTIEILPSDMGGDYDALETLMASRPDILNHNIETVRRLTPRVRARATYDRTLEFLRRSKELQPDIPTKSSIMVGLGETIEEIYETMDDLRANDVDILTIGQYLQPSRKHLKVQKYYTPLEFGKLRKVAMDKGFKHCQAGPLVRSSYHADEQVNEAAKEKQRQGEAQLNS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIB2_YEAST
Sequence: MEDSNNEASDDFNNLLNKEIESAKEVKLRKFANRNNNRNENSSKVKDASGFRLRVIQTDGHKTKKTDPDYEVTIDGPLRKIEPYFFTYKTFCKERWRDRKLVDVFVSEFRDREPSYYSKTIAEGKVYLNDEPANLDTIIRDGDLITHKVHRHEPPVTSKPIDIVFEDEDILVIDKPSSIPVHPTGRYRFNTITKMLERQLGYSVHPCNRLDKPTSGLMFLAKTPLGADRMGDQMKAREVTKEYVARVKGEFPIGIVEVDKPVRSVNPKVALNAVCEMSDENAKHAKTVFQRVSYDGQTSIVKCKPLTGRTHQIRVHLQYLGFPIANDPIYSNPDIWGPDLGRGGLQNYDDIVLKLDAIGKTNPAESWIHPHSEGEYLLGRQCEECEAEMYTDPGTNDLDLWLHAFRYESLERNSDTQKPLWSYRTKYPEWALEPHRRYMEMAVKEAGKCGPTKTAFSVGAVLVHGTQVLATGYSRELPGNTHAEQCALIKYSQLHPNCPTIVPMGTVLYTTMEPCSFRLSGNEPCCDRILATQGAIGTVFVGVMEPDTFVKNNTSLNKLESHGVNYIQIPGYEEECTIIAFKGHDNSDDKA
What is the function of this protein?
Involved in riboflavin biosynthesis.  Converts 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1H,3H)-pyrimidinedione 5'-phosphate.
What are the official names of this protein?
Bifunctional protein RIB2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO13B_YEAST
Sequence: MSDFEIIVGISSLLQVIILNIQNMLEVLLEYIGIHKRRVDISTYYDNVYFFFHFICYHLLSYCIINLRISASFICDSCSLIIMSPSYAVCDNILVT
What are the official names of this protein?
Putative uncharacterized protein YOL013W-B.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACCO1_DORSP
Sequence: MESGSFPVINMELLQGSQRPAAMALLRDACENWGLYELLNHGISHELMNRVETVNKEHYRRFREQRFKEFASKTLDTVENVEPENLDWESTFFLRHLPTSNISQIPDLDDDCRSTMKEFALELENLAERLLDLLCEDLGLEKGYLKKVFCGGSDGLPTFGTKVSNYPPCPKPELIKGLRAHTDAGGIILLFQDDKVSGLQLLKDGEWIDVPPVRHSIVVNIGDQLEVITNGKYKSVLHRVVAQTDGNRMSIASFYNPGSDAVIFPAPALVEKEAEEKEEKKKEIYPKFVFQDYMNLYIRKKFEAKEPRFEAMKSMEIVMSSQPIPTA
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase 1, ACC oxidase 1, Ethylene-forming enzyme, EFE.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: EPHB3_HUMAN
Sequence: MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Generally has an overlapping and redundant function with EPHB2.  Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex.  In addition to its role in axon guidance also plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses.  Controls other aspects of development through regulation of cell migration and positioning.  This includes angiogenesis, palate development and thymic epithelium development for instance.  Forward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca.  Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt.
What are the official names of this protein?
Ephrin type-B receptor 3, EPH-like tyrosine kinase 2, EPH-like kinase 2, Embryonic kinase 2, EK2, hEK2, Tyrosine-protein kinase TYRO6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite.
Protein: Y2548_BURCM
Sequence: MLSPCLAAPATECRDPADAPAAPARHTGPARPRKRRPRNWKPHLPRERLLERGPAALTDAELIALLLGTGGGGRDVFASARALLARFGDSLRDMLDAEPDVFATHPGIGTARSAVLIAVTEIVRRALVEKARERLQIDSPGAVEDYLRLRIGTRPHEVFVTLYLDARHGLIDVEESARGSLTRMAVYPREIVRRALVLNAAALIIAHNHPSGAVQPSAEDRRLTRVLHEALALIDAKLLDHVVVGTADTFSFARAGWL
What are the official names of this protein?
UPF0758 protein Bamb_2548.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: PURA_CHLPM
Sequence: MESKPFSLPSQSATVLIGTQFGDEGKGKLVDYLSDQYDIVVRYQGGANAGHTICFDGKSVVLHLIPSGIFNEKCVCVIGNGVVIDPVALLEEIATVEALGYEVKGRLFISHNAHLIMPYHKRLDSLSESAQGDQKIGTTGRGIGPSYEDKFARKGIRVVDLLNAEVLQEKLRENLAQKNRLFTTIYDGEEIDVESMVREYEEFDKIIDPYITNTQLYLNRQLREGRTVLLEGAQGSLLDVDHGTYPFVTSSNPTSGGACTGSGIAPNHIGKVIGVCKAYMTRVGNGAFPTELFDETGEELGRVGHEFGATTGRKRRCGWIDLVAMRYAVAVNGITELALTKLDVLDGFEEIQVCNSYTLDGKEIFDFPTDHETLSRVKPVLTPMKGWMASNADARNFEEMRPAAKQFVEFLENELEVPVTFISVGPGRNETVFR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_CUPNH
Sequence: MTATHRGAQADASAPAGPLPPEAAAKRVAWLRDELDRHNYQYYVLDAPTIPDAEYDALFSELQALELEHPELQTPDSPTQRVGGEPLSAFDSVRHRVPMLSLNNGFADDDVLNFDRRCAQGLGRTAPAAGEQDLFSAADAVEYACELKFDGLAMSLRYEDGRLVQAATRGDGETGEDVTVNVRTIKAIPLKLRGQAPAVLEVRGEVFMYRGDFDKLNERQAEAGEKTFVNPRNAAAGSLRQLDPRITAKRPLSFFAYGLGELQGVDRPPTHSAMLDGFAALGLPVCKDRAVVKGAQGLLDFYRDIGQRRDALPYDIDGVVYKVNALAEQERLGFVSRAPRFALAHKFPAQEMTTIVEDIEVQVGRTGAITPVARLKPVFVGGVTVTNATLHNEDEIRRKDVHIGDTVIVRRAGDVIPEVVAVVTERRPDDARAFVMPTACPVCGSHIEKLEDEAIARCTGGLICAAQRKQALLHFAQRRAMDIEGLGDKLVEQLVDQGIVRTPADLFKLGVAKLAALERMADKSAANLVAAIDASRETTMNRFIFALGIRHVGEATAKDLARHFGKLDALMAADEAALLEVNDVGPVVAQSIAHFFAEPHNVEVIEQLRAAGVHWTESEPVAKAPAPLSGKTFVLTGTLPTMSREDAKELLEAAGAKVAGSVSKKTDYVVAGAEAGSKLDKAEALGVPVLDEAGMLALLAEAGAAPAQE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SYI_SERP5
Sequence: MSDYKNTLNLPETGFPMRGDLAKREPGMLQRWYEQDLYGMIRTAKKGKKSFILHDGPPYANGSIHIGHSVNKILKDIIIKSKGMSGFDSPYIPGWDCHGLPIELKVEQLYGKPGEKLTAAEFRIKCREYAAEQVEGQKKDFIRLGVLGDWDRPYLTMDFKTEANIIRALGKIISNGHLLKGAKPVHWCTDCRSSLAEAEVEYYDKTSPSIDVAFHAVDAAAVATKFGVTRFNGPVSLVIWTTTPWTLPANRAISLHPEFAYQLVQVEGQCLILAAELVESVMKRAGITHWEVLGSCKGADLELMRFEHPFMGFDVPAIMGEHVTLDAGTGAVHTAGGHGPDDFVISQKYGLEIANPVGPNGCYLTGTHPLLDGKFVFKANDLIVDLLREKDALLHVEKLVHSYPCCWRHKTPIIFRATPQWFISMDQKGLRKQSLEEIKGVQWIPEWGQARIETMVANRPDWCISRQRTWGVPMSLFVHKDTEQLHPRSVELMEEVAKRVEQDGIQAWWDLDAADILGADAADYVKVPDTLDVWFDSGSTHSSVVDVRPEFNGHGADMYLEGSDQHRGWFMSSLMISTAMKGKAPYKEVLTHGFTVDGQGRKMSKSIGNTISPQDVMNKLGGDILRLWVASTDYTGEIAVSDEILKRSADSYRRIRNTARFLLANLNGFEPSTDCVAPEEMVVLDRWAVGRALAAQQDIEKAYANYDFHEVVQRLMQFCSVEMGSFYLDIIKDRQYTAKSDSVARRSCQTALFHIAEALVRWMAPIMSFTADEIWAFLPGKRAQYVFTEEWYDGLFGLAEGEGMNDSFWAELLKVRGEVNKVLEQARADKRLGGSLEAAVTLYADSELAERLNSLQDELRFVLLTSGARVAPLADAPADAQAAELVKGLKIAFSTAEGEKCPRCWHYTTDIGLVAEHADLCGRCVVNVAGDGEKRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEA_ASHGO
Sequence: MSPSVRDARNDLASLQQQAAAEAEDIRRWWSQPRWAGTKRVYTAEDIVKRRGTFPVVEYPSSVMADKLVETLARHSRNGTVSQTFGVLDPVQMTQMVKYLDTIYVSGWQCSATASTSNEPGPDLADYPMDTVPNKVEHLFMAQLFHDRKQREARLSCTTQRELDQLGPEIDYLRPIVADADTGHGGLTAVFKLTKMFIERGAAGIHMEDQSSSNKKCGHMAGRCVIPVQEHISRLVTVRMCADVMHSNLVLVARTDSEAATLLSSNIDARDHYYIVGASNPEVTVPLIEVLDAAQQAGASGDRLAQLEEDWCKKAKLRLFHEAFADQVNASPSIKDKAGVIAKFNSQIGPQTGASIREMRKLGRELLGQDVYFDWDLPRAREGLYRYKGGTQCAIMRARAFAPYADLVWFESNFPDFQQAKEFAQGVREKFPNKWMAYNLSPSFNWPKAMPPKEQENYIQRLGEIGYVWQFITLAGLHTNALAIDNFSREFSRFGMRAYAQGIQQREMDEGVDVLKHQKWAGAEYVDSILKLAQGGVSSTASMGKGVTEEQFGSSNGAKL
What is the function of this protein?
Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle.  Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available.  Acts also on 2-methylisocitrate.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, Threo-D(S)-isocitrate glyoxylate-lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: Y1379_LYSSC
Sequence: MPKIKWTNKDFNVFKIDGLEQRMNALNDHVRPKFHQLGDDFATYFSSKLGEEFFPHVAKHARRTVNPPQDSWVAFAPYKRGYKSLPHFQIGLWHSHLFIVLAIIYEAPQKNVMAERLLAHPSLFEQLSDDFIVSGDHMSPEAISLEEAKEDKLKELLLRLRDVKKGEFLIGRHIPKDQATKLTASEFHQLTEQTFNSLLPFYNVIVGKDLK
What are the official names of this protein?
UPF0637 protein Bsph_1379.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: ATPB_MYCTO
Sequence: MTTTAEKTDRPGKPGSSDTSGRVVRVTGPVVDVEFPRGSIPELFNALHAEITFESLAKTLTLEVAQHLGDNLVRTISLQPTDGLVRGVEVIDTGRSISVPVGEGVKGHVFNALGDCLDEPGYGEKFEHWSIHRKPPAFEELEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELAEANVLKDTALVFGQMDEPPGTRMRVALSALTMAEWFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILDPSVVGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRARRIERFLSQNMMAAEQFTGQPGSTVPVKETIEAFDRLCKGDFDHVPEQAFFLIGGLDDLAKKAESLGAKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNY1_BDEBA
Sequence: MEIVISAIIGLLIGGTVVFVIKRLQDNNKKKSARFEAERIVNKANSEAAKIKKESENKAKDFESRARKNVEQDIHKQKSTLKNKESQLERRLKEVEDQFKQKMEENERYLNSLKDREEKIAISENRIKDLEKKGEAHIGELKQKLESVAAMSQDEARRQLLTALEDEAKQEAAKKIAQIEEEANKESEKKAKRILATALSRFASEYTSERTVSVLALPNDEMKGKIIGREGRNIRTLEAHCGVDLIVDDTPEAVVISGFDPVRRELARRTIEKLMEDGRVHPARIEEVAEKQRNELMKSMKEEGERHVMELGIPNMHPELVKIIGGLKYRSYQGQNALNQSLEVATIAGLLAAELGVSVKLARRAGLLHNIGKAIDHTVEGSYAFVGAEAAKKYNESEDVCHAIRAHDEEEKPHSILAWIVHAAYTLSSSRPGARRPQMDTFIHRLEDLESIGNSFDGVLKTLALQAGKDIRVLVESSRVTDDQAVMLSRDIARKIEREMPQAGQVKVTVVRETRSVEHAR
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y 1, RNase Y 1.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: OCAD2_HUMAN
Sequence: MASASARGNQDKDAHFPPPSKQSLLFCPKSKLHIHRAEISKIMRECQEESFWKRALPFSLVSMLVTQGLVYQGYLAANSRFGSLPKVALAGLLGFGLGKVSYIGVCQSKFHFFEDQLRGAGFGPQHNRHCLLTCEECKIKHGLSEKGDSQPSAS
What are the official names of this protein?
OCIA domain-containing protein 2, Ovarian carcinoma immunoreactive antigen-like protein.
What are the subcellular locations of this protein?
Endosome.
Protein: SYTC_ENTBH
Sequence: MSIYVTFKGQVQKICISSGTILQELISTHYPNKNIIACAIDGIMADINTEINENQKIELYDFDSKEGQHVYWHSSAHILGNALVNLYQCKLVNGPALDEGFYYDIDIERPIREEDFADIEKEMQRIINKNIDFRKKMIKKDDLLKMYKDNDYKVHFINNIPDNLISVYYNDEFYDMCQGPHIQSTGLVKAFKILKSSSCYFLNSADNQILQRIYGISFPNKTLLKEYEEKVQKAKEMDHRKIGKELNLYFFHEYSPGSCFWLPDGVVIYNRLMEFLRKEYIKRGFKEVITPNIFHIDLWKESGHYQNYKENIYGISGEDFALKPMNCPGHCIIFKSVERSYKELPLRYADFGVLHRNECSGSLTGLTRVRRFQQDDAHIFTSKSSIKEEIENAIGFLKTVYSIFNFKYELFLSTRPTKFLGTIEEWDVAEKSLKDAIIDSGHTYTLNEGDGAFYGPKIDIILHDILNRKIQCATIQLDFQLPQRFDLKFKNELGMYETPVIIHRAILGSFERFIAILIESYGKHLPFWLHPRQVGLVTIDCKHENYMYTVEKSMLNVVLDLGIRKYTDPKDTLNKKIRKATLDGCKIICILGDKEMEKNEVNVRIGNKTRTYKIEELLEKIKVSIETKKEFIFN
What are the official names of this protein?
Probable threonine--tRNA ligase, cytoplasmic, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACHG_XENLA
Sequence: MDTVLLLVSLCISAAFCNNEEERLLNDLMKNYNKNLRPVEKDGDIISVSIKLTLTNLISLNEKEEALTTNVWVEMQWKDYRLSWDPNDYHGISMMRIPSTSVWLPDVGLENNVDGTFDIALYTNTLVSSDGSMYWLPPAIYRSSCPVVVTYFPFDWQNCSIVFQSQTYSANEIELLLTVDEQTIEWIEIDPEAFTENGEWAIKHMPAKRIINHRLPRDDVNYQQIVFYLIIQRKPLFYIINIIVPCVLISFVSILVYFLPAKAGGQKCTVSINILLAQTVFLFLVAQKIPETSTSVPLIVKYLTFLMVVTITIVANAVIVLNISLRTPNTHSMSSTVRELCLRTVPRLLRMHLRPTDAAPPLAPLMRRSSSLGLMMKADEYMLRKPRSQLMFEKQKERDGLMKVVLDKIGRGMENNTSDDLVHSLNHAAPEIRTCVEACCHIASATREKNDFKSENEEWILMGRVIDRVCFLVMCFVFFLGTIGTFLAGHFNQAPAHPFPGDSKLYQPST
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Gamma/CHRNG sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.