PharMolix/UniProtQA huggingface dataset:
Protein: HCK_RAT
Sequence: MGGRSSCEDPGCPRGEGRVPRMGCVKSRFLREGSKASKIEPNANQKGPVYVPDPTSPKKLGPNSINSLPPGVVEGSEDTIVVALYDYEAIHREDLSFQKGDQMVVLEESGEWWKARSLATKKEGYIPSNYVARVNSLETEEWFFKGISRKDAERHLLAPGNMLGSFMIRDSETTKGSYSLSVRDFDPQHGDTVKHYKIRTLDSGGFYISPRSTFSSLQELVVHYKKGKDGLCQKLSVPCVSPKPQKPWEKDAWEIPRESLQMEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANLMKTLQHDKLVKLHAVVSQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYSIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQP
What is the function of this protein?
Non-receptor tyrosine-protein kinase found in hematopoietic cells that transmits signals from cell surface receptors and plays an important role in the regulation of innate immune responses, including neutrophil, monocyte, macrophage and mast cell functions, phagocytosis, cell survival and proliferation, cell adhesion and migration.  Acts downstream of receptors that bind the Fc region of immunoglobulins, such as FCGR1A and FCGR2A, but also CSF3R, PLAUR, the receptors for IFNG, IL2, IL6 and IL8, and integrins, such as ITGB1 and ITGB2.  During the phagocytic process, mediates mobilization of secretory lysosomes, degranulation, and activation of NADPH oxidase to bring about the respiratory burst.  Plays a role in the release of inflammatory molecules.  Promotes reorganization of the actin cytoskeleton and actin polymerization, formation of podosomes and cell protrusions.  Inhibits TP73-mediated transcription activation and TP73-mediated apoptosis.  Phosphorylates CBL in response to activation of immunoglobulin gamma Fc region receptors.  Phosphorylates ADAM15, BCR, ELMO1, FCGR2A, GAB1, GAB2, RAPGEF1, STAT5B, TP73, VAV1 and WAS (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase HCK, Hematopoietic cell kinase, Hemopoietic cell kinase, p56-HCK, p56Hck, p59Hck.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Isoform 1]: Membrane; Lipid-anchor. Membrane, caveola. Lysosome. Cell projection, podosome membrane; Lipid-anchor. Cytoplasm, cytosol. Note=Associated with specialized secretory lysosomes called azurophil granules. A fraction of this isoform is found in the cytoplasm, some of this fraction is myristoylated (By similarity). SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane; Lipid-anchor. Membrane, caveola; Lipid-anchor. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Golgi apparatus. Cytoplasmic vesicle. Lysosome. Nucleus. Note=A small fraction of this isoform is associated with caveolae. Localization at the cell membrane and at caveolae requires palmitoylation at Cys-3. Colocalizes with the actin cytoskeleton at focal adhesions (By similarity).
Protein: ZBT32_PANTR
Sequence: MSLPPIRLPSPYGSDRLVQLAARLRPALCDTLITVGGQEFPAHSLVLAGVSQQLGRRGQWALGEGISPSTFAQLLNFVYGESVELQPRELRPLQEAARALGVQSLEEACWRARGDRAKKPDPGLKKHQEEPEKPSRNAERELGDPGEKQKPEQVSRTGGREQEMLHKHSPPRGSPEMAGATQEAQQEQTRSKEKHLQAPVGQRGADGKHGVLMWLRENPGGSEESLHKLPGPLPPAGSLQTSVTPRPSWAEAPWLVGGQPALWSILLMPPRYGIPFYHSTPTTGAWQEVWREHRIPLSLNAPKGLWSQNQLASSSPTPGSLPQGPAQLSPGEMEESDQGHTGALATCAGHEDKAGCPPRPHPPPAPPARSRPYACSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRXXLCGAGCPSLASMQAHMRGHSPSQLPPGWTIRSTFLYSSSRPSRPSTSPCCPSSSTT
What is the function of this protein?
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence.  May function as a transcriptional transactivator and transcriptional repressor.  Probably exerts its repressor effect by preventing GATA3 from binding to DNA.  May play a role in regulating the differentiation and activation of helper T-cells (By similarity).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 32.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Note=Located in nuclear speckles.
Protein: RNP1B_XENLA
Sequence: MAPSPSKRKERSEDKAKERGKEKAPGKEATDKDRGRDKAKKRRSASSGSSSSSRSRSSSSSSSSSGSSSGSSSGSSSSASSRSGSSSSSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKQPKRDEKERKRRSPSPRPTKVHIGRLTRNVTKDHILEIFSTYGKIKMIDMPVDRYHPHLSKGYAYVEFEAPEEAEKALKHMDGGQIDGQEITASAVLTPWPMRAMPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPARRRHRSRSSSNSSR
What is the function of this protein?
Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs.  The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  Putative component of the spliceosome which enhances the formation of the ATP-dependent A complex of the spliceosome.  May participate in mRNA 3'-end cleavage.  Also mediates increase of mRNA abundance and translational efficiency (By similarity).
What are the official names of this protein?
RNA-binding protein with serine-rich domain 1-B.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein.
Protein: RS18_ECOL6
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ADE_BORPA
Sequence: MYDWLNALPKAELHLHLEGTLEPGLMFELARRNGVALPWPDVESLRRAYDYDNLQEFLDLYYRGAEVLRTEQDFYDLTWAYLLKCREQNVVHTEPFFDPQTHTDRGIAFETVLAGITQALEDGRTQLGIQGGLILSFLRHLPEEAAMRTLEQALPYRDAFIAVGLDSSERGFPPRLFQRVFERARAAGLPAVAHAGEEGPPEYIWEALDLLQVRRIDHGVRAAEDERLIERLIDTQIPLTVCPLSNTRLRVFDSMAEHNILELLERGVKVTVNSDDPAYFGGYITENFHALHEHLGMTQDQARRLAANSMDARLAGG
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: APY1_CAEEL
Sequence: MTQESNSNFFNFLLFGFVTAIAFYSGTQFNKSSEQEEHINHANLYSVKKFDDGAKEYSIMLITDLDHDSKDGKKWKSLVSRGFLKVSADHKHADIHFDKDSEYYVDTNIAAGGRAMELSDLAVFNGKLYSIDDRTGLIYQISDKKALPWVLLNDGPGNVVKGFKGEWITVKDTELIVGGLGKEWTTTDGVYVNDHPMWVKHVSAHGAVHHENWKDVYIRVRRAAGIEYPGYMIHEAVQWSAIHRKWFFLPRRMSNEKYSEAEDENRGTNVLVIGNEELTDFEVVRVGSENNKSRGFAAFQFVPNTHHQLIVAIKSEEKDGKPVASYASVFDIHGNVILDEYLLHGPYKYEGIAFA
What is the function of this protein?
Hydrolyzes UDP and to a lesser extent GDP.  By preventing the accumulation of NDP, may promote the reglucosylation of incompletely folded glycoproteins in the endoplasmic reticulum following the unfolded protein response.
What are the official names of this protein?
Apyrase apy-1, Uridine-diphosphatase, UDPase.
What is the protein family that this protein belongs to?
Belongs to the apyrase family.
What are the subcellular locations of this protein?
Endomembrane system; Single-pass type II membrane protein.
Protein: RUVV_VACCC
Sequence: MSSPMSKKDYSSEIICAFDIGAKNPARTVLEVKDNSVRVLDISKLDWSSDWERRIAKDLSQYEYTTVLLERQPRRSPYVKFIYFIKGFLYHTSAAKVICVSPVMSGNSYRDRKKRSVEAFLDWMDTFGLRDSVPDRRKLDDVADSFNLAMRYVLDKWNTNYTPYNRCKSRNYIKKM
What is the function of this protein?
Plays a role in DNA replication by cleaving viral DNA concatamers to yield unit-length viral genomes.  The concatamer junctions contain inverted repeat sequences that can be extruded as cruciforms, yielding Holliday junctions that A22 protein cleaves.
What are the official names of this protein?
Resolvase OPG149.
What is the protein family that this protein belongs to?
Belongs to the RuvC family. Poxviruses-type subfamily.
Protein: O16C_CONAB
Sequence: VLIIAVLFLTACQLTTAETSSRGKQKHRALRSTDKNSKLTRGCTPPGGACGGHAHCCSQSCNILASTCNA
What are the official names of this protein?
Conotoxin AbVIC.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COX3_ANTMR
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLTMWFHFNSMTLLTLGLTTNMLTMYQWWRDIIRESTFQGHHTPNVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMLQALFITISLGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IGF1_SHEEP
Sequence: MGKISSLPTQLFKCCFCDFLKQVKMPVTSSSHLFYLALCLLAFSSSATAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKAAKSARSVRAQRHTDMPKAQKEVHLKNTSRGSAGNKNYRM
What is the function of this protein?
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.  May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts.  Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.  May play a role in synapse maturation.  Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb.  Acts as a ligand for IGF1R.  Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways.  Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4.  Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.  Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (By similarity).
What are the official names of this protein?
Insulin-like growth factor I, IGF-I, Somatomedin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGH_PSEA8
Sequence: MNRLMIVSLLGIATALGGCVNPPPKPNDPYYAPVLPRTPLPAAQNNGAIYQAGFEQNLYDDRKAFRVGDIITITLNEKTQASKKANSDIQKDSKTKMGLTSLFGSGMTTNNPIGGGDLSLSAEYGGSRDAKGDSQAGQSNSLTGSITVTVAEVLPNGILSVRGEKWMTLNTGNELVRIAGLVRADDIATDNTVSSTRVADARITYSGTGAFADASQPGWLDRFFLSPLWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: LPXK_ECO55
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTSLASGN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: LEUC_ECO5E
Sequence: MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGILLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: Y5045_PSEPG
Sequence: MKTLAPSYLKHQFLIAMPHMADPNFAQTLTYIVEHNEHGAMGLVVNRPQELSLADILEQLRPDEMPPASTSQVPIYQGGPVQTDRGFVLHSSECSFQATVALEGLSLTTSQDVLLAIAAGVGPKQSLITLGYAGWEAGQLEAELADNAWLNCPFDPEIIFGMANDLRLEAAAASLGINLHLLTSQAGHA
What are the official names of this protein?
UPF0301 protein PputGB1_5045.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: NUOC_SALTO
Sequence: MSAPQDRTDDGGVPVPVTPAGATGGAPAELPPSSPAGRGMFGDQGTGDVSGYGGLVRPQRSIEAATRPYGGYFDEVADALEEAYPAFGEAIEKVVVDRGELTLHIRPERIAEVCQVMRDDLSLRFELCSSVSGVDYLGADACRLHVVYQLTSMTYRRQVRLEAAVSAENPHLPSVTSVYPTADWQERETYDMFGVIFDGHPGLTRILMPDDWEGHPQRKDYPLGGVPVEYKGAEIPPPDRRRSYQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYSD_MARMS
Sequence: MTEARLTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLAMKAFYPGKPPFPLMHVDTGWKFKEMITFRDEMVSKLGLELIVHQNQEGVEQGIGPFTHGSSKHTDVMKTQGLKQALDKYGFDAAFGGARRDEEKSRAKERVYSFRDKQHRWDPKNQRPELWNIYNGKVNKGESIRVFPLSNWTELDIWQYIYLESIPIVPLYFSEKRPVVERDGTLIMVDDERMPLNGEVPEMKSVRFRTLGCYPLTGAVESEAATLPEIIQEMLLTKSSERQGRMIDHDSSGSMEEKKKQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: GLMM_ACTP7
Sequence: MAERKYFGTDGVRGKVGQFPITPDFALKLGWAAGKILATQGTKQVLIGKDTRISGYMLESALEAGLAAAGLSAAFVGPMPTPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSSVGEKLPDEVEEAIEALLDQPMDCVESAQLGKAMRINDAAGRYIEFCKGTFPANASLKGYKIVVDCANGATYHIAPNVMRELGAEVIEIGTKPDGLNINEKCGATDIKALQKVVVESGADVGLAYDGDGDRIMMVDHLGNKVDGDQILFIIAREALRSGKLHGGVVGTLMSNMGLEVALKHLAIPFTRANVGDRYVLEQLKEKGWKLGGENSGHIIVLDKNTTGDGIIASLEVLAAMEAHKMSLNDLARAVPLFPQVLINVRFEGGKNPLESDAVKAVAADVEKRLAGRGRILLRKSGTEPLIRVMVECEDGALAQSCAEEIVEAVKSN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CHS6_USTMA
Sequence: MSTKDAHDPFATPLETITHDPLAETAGLKADYDKRAYGEANPALMGTLEKDDMANRPIDAVEEVPTTSIRKWWVRLTWFTTWWIPSFVLSKCGGMKRPDVQMAWREKFTICAIIFWLCAIILFYIIAFGRLLCPDYDKAWNLSQLSQHAGENDYYAAVRGTVYDFSKFYKGDHSDITNLQTSSDLMLQLAGQDLTGYFPVPLSVGCQSLVSDTSLALMPTANNTPLISQAIHTSGPLQGDTSSKLHDINWYPDRFLPFVKKLRKGYYVYSKKDLANQGQWRNWAVIHGKVYDLSNYLNTVSTYQTNPAYSFLDSSIVSLFKSQAGSDITADFEDAMSTFNQTYRGATQACLDNVFYVGRTDFRDTARCEVQNYLLLAFSVLLVTTVLAKFIAALQLGTKRSPEQQDKFVICQVPCYTEGEEELRKTIDSLAGLEYDDKRKLLFLICDGMIVGSGNDRSTPRIVLDILGVDPKIDPEPLMFKSVAEGSKQLNYAKVYSGLYEFEGHVVPYIVVVKVGRPSERSRPGNRGKRDSQILLMRYLNRVHFDAPMFPLELEIYHQMKNVIGIDPAFYEYILMVDADTRVEADGLNRLVANCADDSSIIAICGETTLDNAEGSWWTMIQVYEYYISHHLSKAFESLFGSVTCLPGCFSLYRIRSSDKGRPLFISNRIIDDYSENRVDTLHKKNLLHLGEDRYLTTLVLKNFPSFRTKFVPDAKALTSAPDRFGVLLSQRRRWINSTVHNLAELVLMPELCGFCLFSMRFIVFIDLLGTVILPATAVYLVYLIVTVATKSAPIPYISIAMIAAVYGLQAILFLLKRQWQYIGWLVIYILAYPVFSFFLPIYSFWHMDDFSWGNTRIVVGEKGNKKIVAGTDDEPYDDTMIPLKRFSEYQREVWEEEAAAPSMRSGMTGASGPFGNSQAILHSGPPSVYRAGGSAYAGSVAGSDYGAGLGDYYQNTNVLQKPAHSRQTSAAALSQMGGSQAASMMFGTGTPSVYGMAGMGSMYGMPGSSASMYGLPNPMMNTTASMYGLPPMLANPLGANHSPAHSDIGVSMPVSQQNTGGSHIWAQPPEAATVAANSGRGSGMQARPVSTLSALNATNPFGVTAVARALAVNEASDPTDEEIKSAVQTYLANQPSLMNVTKRSVREALVAAFPNAELSYKKSMINKAIDDTLSGGAQA
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 6, Chitin-UDP acetyl-glucosaminyl transferase 6, Class-V chitin synthase 6.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class V subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=A constitutive cytoplasmic pool is present that localizes to intracellular microvesicles termed chitosomes. Chitosomes constitute a separate secretory route distinct from the typical secretory pathway and serve as a vehicle for delivering the enzyme to the sites on the cell surface where polysaccharide sythesis takes place. Localizes to septa of yeast-like cells and to the basal septum separating the living tip cell from the vacuolated part in hyphae. Also localizes to the growing bud tip in yeast-like cells and in a tip-ward gradient at the hyphal apex.
Protein: CARP4_CANAW
Sequence: MFLQNILSVLAFALLIDAAPVKRSTGFVTLDFNVKRSLVDPKDPTVEVKRSPLFLDIEPTEIPVDDTGRNDVGKRGPVAVKLDNEIITYSADITIGSNNQKLSVIVDTGSSDLWVPDSNAVCIPKWPGDRGDFCKNNGSYSPAASSTSKNLNTPFEIKYADGSVAQGNLYQDTVGIGGVSVRDQLFANVRSTSAHKGILGIGFQSNEATRTPYDNLPITLKKQGIISKNAYSLFLNSPEASSGQIIFGGIDKAKYSGSLVDLPITSDRTLSVGLRSVNVMGQNVNVNAGVLLDSGTTISYFTPNIARSIIYALGGQVHYDSSGNEAYVADCKTSGTVDFQFDRNLKISVPASEFLYQLYYTNGEPYPKCEIRVRESEDNILGDNFMRSAYIVYDLDDRKISMAQVKYTSQSNIVGIN
What are the official names of this protein?
Candidapepsin-4, ACP 4, Aspartate protease 4, Secreted aspartic protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRB_PSESM
Sequence: MTPLDAKRPLQLNHQGQLRHFLSLDGLPRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQRLSADVITLNVSTSSTSKGETLFDTLRNLEAMAADMFVVRHADSGAAHFIAEHVCPDVAIINGGDGRHAHPTQGMLDMLTIRRHKGGFENLSVAIVGDILHSRVARSNMIALKALGCPDIRVIGPKTLLPVGVEQYGVKVYTDLNEGLKDVDVVIMLRLQRERMTGGLLPSEGEFYRLFGLTTARLAGAKPDAIVMHPGPINRGVEIESAVADGAHSVILNQVTYGIAIRMAVLSMAMSGQNAQRQFEQENAQ
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: NTPPA_RHORT
Sequence: MTHGDNRDGPGRETRSSGPLVLASASPRRVDLLAQIGLVPDAIDPADLDETPAADELPRPYAERVARAKALAVAPRHPGAWVLAGDTVVARGRRILPKAEDAKTAKTCLEMLSGARHRVIGAIALVTPEGRLIERSVVSQVAFKRLSAAEIAEYLAGDEWRGKAGGYAIQGRAAAFVRWLEGSHSNVVGLPLFETNALLAGTGYRPGRDG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLR31_BRELC
Sequence: MLLSRAISVLALLACIRCGVHAQNTEQNLKTQLTTDSAMITSQRLLRTSVDFKDSEERWPTESSRIRSAIKDYFREFPEKVSIAMAIRQIDAHGVRHVEKVLSQYKFPAADQGNIRLAIIHHKAPK
What is the function of this protein?
Secreted effector that triggers a hypersensitive response (HR) in 3 Lactuca saligna accessions (CGN05947, CGN05310, CGN05304).
What are the official names of this protein?
RxLR effector protein BLR31.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: RS15_RICFE
Sequence: MSITQERKQKLIKEYAITENDTGSSAVQCAILTERINNLTEHFKFNHKDHTSRRGLLILVGRRRRLLNYIKKNNVSEYLDLISKLGIRKIK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ATPB_THEMA
Sequence: MAKGSKGFIVSIMGPVVDVKFPEEELPDIYNALEVVNPQTGQKVVLEVEQLIGDGVVRTVAMDSTDGLTKGLEVVDTGAPITAPVGKEVLGRILNVIGEPVDEAGEIKAKERWPIHRPAPELVEQSTEIEILETGIKVIDLLAPFPKGGKIGFFGGAGVGKTVLVMELIRNIAIEHKGFSVFAGVGERTREGNELWLEMQESGVLGNTVLVFGQMNEPPGARFRVALTALTIAEYFRDVEGRDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATDMGELQERITSTRRGSITSVQAIYVPADDITDPAPATTFAHLDATVVLSRRIAELGLYPAVDPLDSSSKILDPAIVGREHYEVARGVQEVLQRYKDLQDIIAILGVEELSPEDKLVVHRARRIQRFLSQPFHVAERFTGRPGRYVPIEETIRGFKEILDGKLDDVPEQAFLMAGNIDEVKERAKEMRS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.