PharMolix/UniProtQA huggingface dataset:
Protein: DCUA_SHIFL
Sequence: MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML
What is the function of this protein?
Responsible for the transport of C4-dicarboxylates during aerobic and anaerobic growth.  Required for the uptake of L-aspartate as a nitrogen source during aerobic growth.  The uptake of L-aspartate in aerobic conditions is coupled to the excretion of fumarate, resulting in the net uptake of nitrogen without carbon uptake.  In addition, during anaerobic growth, catalyzes the uptake of fumarate, malate or aspartate coupled to the export of succinate.  May play a a general role in anaerobic C4-dicarboxylate transport.
What are the official names of this protein?
C4-dicarboxylate transporter DcuA.
What is the protein family that this protein belongs to?
Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GERPB_BACCE
Sequence: MNFYVNQSIIINSIKIDSITTSSVFQIGTAGSIKALSKFSNTGGFTEPLRPLQAKGQIISIKPSTSSS
What is the function of this protein?
Required for the formation of functionally normal spores.  Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor.
What are the official names of this protein?
Probable spore germination protein GerPB.
Protein: GREA_PSYIN
Sequence: MVQYPMTANGAAKLRSELKQLKTVTRPRIVKAIAEAREHGDLKENAEYHAAREQQGFCEGRIQDIEAKLSNARIIDITNITNNGKVIFGATVTIVNVETDAEVTYKIVGDDEANIKINLISVSSPLARGLIGKTLDDEISIVTPGGTIDYEIISVQYIA
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: APAH_PSYIN
Sequence: MATYIVGDVHGCFDELQALLELAQFKKNKDQLWITGDLVGRGPKSLETLRFVKSLGDSAKIVLGNHDLHLLAIHQGIHSDKESDKLSALLNAPDCDELLTWLRFQPLFRRHPEFNFVMVHAGISPQWTIQQAQGYAQEVQNILQGNEFKKLLKNMYGNHPASWNDSSQGIKRLRFIINALTRMRYCLLDGSLEFYSKLAPEQTDSTIIKPWFEINTLDQSSDIIFGHWAALLGTGTKQGIYALDTGCVWGNSLSMLRWQDKKMFSFACQRQRVHSK
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: Y2196_STAAS
Sequence: MEKVYVAGAIPEVGLKLLQEHFEVEMYEGKGLVDKDTLIKGVKNATALISLLSTNVDKDVIDAGKDLKIIANYGAGFNNIDIEYAREKSIDVTNTPKASTNATADLTIGLVLAVARRIVEGDQLSRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAVARRARAFDMDVLYTGPNRKEEKEREIGAKYVDLDTLLKNADFITINAAYNPKMHHLIDTEQFKMMKSTAYLINASRGPIVHEQALVQALKDNEIEGAALDVYEFEPDITDDLKSLNNVVLTPHIGNATFEARDMMSKIVANAAISAVQGEKPQFVVN
What are the official names of this protein?
Putative 2-hydroxyacid dehydrogenase SAS2196.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: IF1_RUEPO
Sequence: MAKEDTLEFPGVVKELLPNATFRVELENGHEIIAHTAGKMRKNRIRVLAGDKVQVEMTPYDLTKGRINYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YZ11_AQUAE
Sequence: MREEVERKIKEVLGVKEETLKYEGVFRRRKRKGAKEYEYLEAKFYDIEEKKIVNVHVPVKKENLVLELDRHWKESKKREKELEKRLKEIISEYKNPDLIREILERLLEEGIRREAKDYAYEKYKKEALELFERFKPYLIKLRRERLKRINLLQALYLLANVKEMFQEKEEELEKVMERAVKTILFRDQNQKLQSPLGVLKNDFFLPKETPYDFLLSRFLQAELEPVLEKLLKAEIEKEETQEAMGEIAEFLTELSEEAKSRVLKVFPSFSQFSKVLYREWKKSGQSLKDFLVDWKSFLEFKGKEAEKEVLNVLSKLNL
What are the official names of this protein?
Uncharacterized protein aq_aa11.
What is the protein family that this protein belongs to?
To A.aeolicus AA07 and AA34.
Protein: RPIA_HAES1
Sequence: MDQLSMKKMAAQAALQYVKPDSIIGVGSGSTVNCFIEVLGTIKETIKGAVAASKASEELLLRQGIEVFSANDVSGLDIYVDGADEINPQKMMIKGGGAALTREKIVAALAKKFICIVDSSKQVDVLGSTFALPIEVIPMARSQVARKLVALGGSPEYRENVVTDNGNVILDVYNFKIMNPIEMEKELNNVAGVVTNGIFALRSADIVIVGTPEGTKIIE
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: DRRC_MYCTU
Sequence: MITTTSQEIELAPTRLPGSQNAARLFVAQTLLQTNRLLTRWARDYITVIGAIVLPILFMVVLNIVLGNLAYVVTHDSGLYSIVPLIALGAAITGSTFVAIDLMRERSFGLLARLWVLPVHRASGLISRILANAIRTLVTTLVMLGTGVVLGFRFRQGLIPSLMWISVPVILGIAIAAMVTTVALYTAQTVVVEGVELVQAIAIFFSTGLVPLNSYPGWIQPFVAHQPVSYAIAAMRGFAMGGPVLSPMIGMLVWTAGICVVCAVPLAIGYRRASTH
What is the function of this protein?
Probably part of the ABC transporter complex DrrABC involved in doxorubicin resistance.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable doxorubicin resistance ABC transporter permease protein DrrC.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MINC_SHEB5
Sequence: MSKPSLELKGASFTLSVLHINSSDLQAVMTELDSKLAQAPQFFLGAPLVVNLSAIQHDSLNLSALKDLLISRQLVIVGITGATTVLSKQAKDLGLAIVKAGKQSSTPPPAPRQTKIVKQNIRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRGKAMAGAAGDTSAVIIAHSLEAELVSIAGQYWLAENLQQHSSDKSGCIRLDGESLMVESLPL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: SDHD_CITK8
Sequence: MENAKMTSLIAQYPLVEDLIALKETTWFNPGTTSLAEGLPYVGLTAQDVQDAHARLARFAPYLAKAFPETAATGGIIESELAIIPAMQQRLEKEYGQKISGELLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTTEDDYSVMLSPEFRQFFSQYSIAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEEDYGVAVEQGRKAAQSDPNCFFIDDENSRTLFLGYAVAGQRLKAQFAQQGRVVDADHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHDAISVQEIGVDNLTAADGLAVGRASGFVGRAMERLLDGLYTLDDRTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCRSTDYQQMHAFSAEQLNHATHLVWATGGGMVPEEEMAQYLAKGR
What are the official names of this protein?
D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: BLA1_ACTPL
Sequence: MLNKLKIGTLLLLTLTACSPNSVHSVTSNPQPASAPVQQSATQATFQQTLANLEQQYQARIGVYVWDTETGHSLSYRADERFAYASTFKALLAGAVLQSLPEKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGVEQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKTILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQFTEEAKFNNKLVEDAAKQVFHTLQLN
What are the official names of this protein?
Beta-lactamase ROB-1.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: GLMM_STRA3
Sequence: MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETDRPRVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGSDGFKLDDDRELEIEALLDAKEDTLPRPSAQGLGTLVDYPEGLRKYEKFMESTGIDLEGMKVALDTANGAATASARNIFLDLNADISVIGDQPDGLNINDGVGSTHPEQLQSLVRENGSDIGLAFDGDSDRLIAVDENGEIVDGDKIMFIIGKYLSDKGQLAQNTIVTTVMSNLGFHKALDREGIHKAITAVGDRYVVEEMRKSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLTKVMKETGKKLSELASEVTIYPQKLVNIRVENNMKDKAMEVPAIAEIIAKMEEEMDGNGRILVRPSGTEPLLRVMAEAPTNEAVDYYVDTIADVVRTEIGLD
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SEPT4_RAT
Sequence: MIKHFLEDNSDDAELSKFVKDFPGSEPCHPTESKTRVARPQILEPRPQSPDLCDDDVEFRATLWSQPSDSQQYFCPPAPLSPSSRPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWRPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPSEVDRKKCKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQRQMKETH
What is the function of this protein?
Filament-forming cytoskeletal GTPase.  Pro-apoptotic protein involved in LGR5-positive intestinal stem cell and Paneth cell expansion in the intestines, via its interaction with XIAP (By similarity).  May also play a role in the regulation of cell fate in the intestine (By similarity).  Positive regulator of apoptosis involved in hematopoietic stem cell homeostasis; via its interaction with XIAP (By similarity).  Negative regulator of repair and hair follicle regeneration in response to injury, due to inhibition of hair follicle stem cell proliferation, potentially via its interaction with XIAP (By similarity).  Plays an important role in male fertility and sperm motility (By similarity).  During spermiogenesis, essential for the establishment of the annulus (a fibrous ring structure connecting the midpiece and the principal piece of the sperm flagellum) which is a requisite for the structural and mechanical integrity of the sperm (By similarity).  Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development (By similarity).  Required for dopaminergic metabolism in presynaptic autoreceptors; potentially via activity as a presynaptic scaffold protein (By similarity).
What are the official names of this protein?
Septin-4, Apoptosis-related protein in the TGF-beta signaling pathway, Arts, Bradeion beta, Brain protein H5, CE5B3 beta, Cell division control-related protein 2, hCDCREL-2, Peanut-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle. Cell projection, axon. Cell projection, dendrite. Perikaryon. Note=Found in the sperm annulus, a fibrous ring structure connecting the midpiece and the principal piece of the sperm flagellum (By similarity). In platelets, found in areas surrounding alpha-granules (By similarity). Expressed and colocalized with SLC6A3 and SNCA in axon terminals, especially at the varicosities (By similarity).
Protein: RF3_PSEA8
Sequence: MTTQAAEVAKRRTFAIISHPDAGKTTITEKLLLMGKAIAVAGTVKSRKSDRHATSDWMEMEKQRGISITTSVMQFPYREHMINLLDTPGHEDFSEDTYRTLTAVDSALMVLDGGKGVEPRTIALMEVCRLRDTPIVSFINKLDRDIRDPIELLDEIEAVLKIKAAPITWPIGCYKDFKGVYHLADDRIIVYVPGHGHERIETKVIEKLDSDEARAHLGDLYDNFVEELELVQGACHEFDKDAFLKGEMTPVFFGTALGNFGVDQVLDCIVDWAPQPLSRATHERSVEPTEEKFSGFVFKIQANMDPKHRDRIAFMRICSGKYEKGMKMRHVRLGKDVKIADALTFFSSEREQLEEAYAGDIIGLHNHGTIQIGDTFSEGENFGFTGIPHFAPELFRRVRLKDPLKSKQLRQGLQELAEEGATQVFFPERNNDIILGAVGVLQFDVVASRLKEEYKVECAYEAINVWSARWIECDDEKKLKEFKDKAFENLSVDGGGHLTYLAPTRVNLSLMEERWPDIRFRATREHH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_METM5
Sequence: MLVIPAVDMKNKKCVQLIQGNPDKKHVELDNPPEIAKKWVSEGAEMLHLVDLDGALDGKRVNDEFIEEIIKTSGVPVQIGGGIRSIEDAVYLVEKGAKKVIIGTIAVEKPEIIKELSENIGSEKIMVSLDAKDGKVVIKGWKEKTKYTPVEIGKILEEMGAGSILFTNVDSEGLLNGINIEPTKELVENLKIPIVASGGVTTIDDLLKFKEIGVYGVVVGSAIYKNMINLKDAIEAVK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP3_ROTRF
Sequence: MKVLALRHSVAQVYADTQIYTHDETKDDYENAFLISNLTTHNILYLNYSVKTLQILNKSGIAAIEIQKNDELFTLIRCNFTYDYIDDIVYLHDYSYYTNNEIRTDQHWVTKTNIEDYLLPGWKLMYVGYNGNDTRGHYNFSFKCQNAATDDDAIIEYIYSNELDFQNFILKKIKERMTTSLPIARLSNRVFRDKLFKTLVSDHSRVVNVGPRNESMFTFLDHPSIKQFSNGPYLVKDTIKLKQERWLGKRLSQFDIGQYKNMLNVLTTLYQYYDMYHEKPIIYMVGSAPSYWIHDVKQYSDLKFETWDPLDTPYSDLHHKELFYASDVTKLKDNSILYVDIRTDRENADWKTWRKIVEEQTANNLNIAYKYLSTGKAKVCCVKMTAMDLELPISAKLLHHPTTEIRSEFYLIMDIWDSKNTKRFIPKGVLYSYINNTITENVFIQQPFKLRTLRNEYVVALYALSNDFNNREDVVKLVNNQKNALITVRINNTFKDEPKVGFKDIYDWTFLPTDFETNESIITSYDGCLGMFGLSISLASKPTGNNHLFILSGTNKYFKLDQFANHMSISRRSHQIRFSESATSYSGYIFRDLSNNNFNLIGTNVENSVSGHVYNALIYYRYNYSFDLKRWIYLHSTNKASIEGGRYYEHAPIELIYACRSAREFAKLQDDLTVLRYSNEIENYINKVYSITYADDPNYFIGIKFKNIPYEYDVKVPHLTFGVLNISDSMVPDVVAILKKFKNELFRMDVTTSYTYMLSDEIYVANVSGVLSTYFKLYNAFYKEQITFGQSRMFIPHITLSFSNKRVVRIGSTRLNIDFIYLRKIKGDTVFDMTE
What is the function of this protein?
Counteracts the host innate immune response thanks to its phosphodiesterase that degrades the 5'-triphosphorylated, 2'-5' linked adenylate oligomers produced by the host cell IFN-inducible 2',5'-oligoadenylate synthetase (OAS).  The host RNaseL is therefore not activated.
What are the official names of this protein?
Protein VP3.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP3 family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. There are about 11 to 12 copies per virion.
Protein: MSRB_STAA8
Sequence: MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMLRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: ARGC_XANC8
Sequence: MTVQPTTIGIVGARGHTGAELIKLIAAHPQLQLVFVSSRELAGQRVAEHSDGYEGELRYESLDADAVAAKAADVVILALPNGKAEPFVAAIDANRPQTLLIDLSADYRFDPAWYYGLPELTRHTYAGQRRISNPGCYATAMQLAITPLREQLAGPPQCFGVSGYSGAGTTPSDKNNPALLADNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIHARYLERYAHEPLIEIVDEAPWVSRIAGTQGVQIGGFTMAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELTAIG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRNK_PYRFU
Sequence: MEVNKASLTYDVPEDREYATKRILSLKRPSKIMVIGDVDTGKTTLIVYLANELISRGFKVAIVDADVGQKGILPPATISLALADMKFSSLSELKPLIHYFVGSITPSQFFGEMIVGTMRLSEIGKKFADYVLIDTTGMIYGSGVELKRLKIEAVKPDLILALEKKEELNPIVSGFEDKTIKLKVSENARSYSRSERRQIRQEKWRKYFENAKIVSFSLENVVVTGTSLFQGSDIREEEKSLLERLFKWVILHGRRIGDKYFVVKADVAEVPRVVDKNVVRYFDFEKLSNLLVGLLNEEGLCLGVGIIKGINFGEKRIDILTPVSEIENVREIRFGRIRVREDGEELGILDREAL
What is the function of this protein?
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA).  Exhibits a strong preference for ssRNA (By similarity).
What are the official names of this protein?
Polyribonucleotide 5'-hydroxyl-kinase PF0112, Polynucleotide kinase PF0112.
Protein: CCA32_ORYSJ
Sequence: MADKENSTPASAARLTRSSAAAGAQAKRSAAAGVADGGAPPAKRKRVALSDLPTLSNAVVVAPRQPHHPVVIKPSSKQPEPAAEAAAPSGGGGGSPVSSASTSTASPSSGWDPQYASDIYTYLRSMEVEARRQSAADYIEAVQVDVTANMRAILVDWLVEVADEYKLVADTLYLAVSYLDRYLSAHPLRRNRLQLLGVGAMLIAAKYEEISPPHVEDFCYITDNTYTRQEVVKMESDILKLLEFEMGNPTIKTFLRRFTRSCQEDKKRSSLLLEFMGSYLAELSLLDYGCLRFLPSVVAASVVFVAKLNIDPYTNPWSKKMQKLTGYKVSELKDCILAIHDLQLRKKCSNLTAIRDKYKQHKFKCVSTLLPPVDIPASYLQDLTE
What are the official names of this protein?
Cyclin-A3-2, G2/mitotic-specific cyclin-A3-2, CycA3;2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: YLNA_SCHPO
Sequence: MAVLSRIMKPYRAFQRLPFELKPLAILIGIAGSTAIFTMGYKIYSDPEIRRSPSWVAQTQQKEETKVKKPQFH
What are the official names of this protein?
Uncharacterized protein PB8E5.10.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RSMJ_COLP3
Sequence: MSPIIASEHLSNIALGYVDSVDSEYAKRLAKKWQFNYLGHVAAASKQPKLEFMLQMHHHALELCKLDEPKLGAIKVDFVEGAVAHRRKFGGGRGQDIAKAVGLKHGFKPHVLDATAGLGRDAFVLASLGCKLTLLERMPVVAALLDDGIERAKLNHEVADIANNMQLIHGSSLEEVDLAIEPDVVYLDPMYPHREKSAAVKKEMRIFQSLVGEDLDADDLLEPALALAKYRVVVKRPSYAPPLANKKPSMSINMKKNRFDVYVKQAIPKPIT
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_CORK4
Sequence: MAVAPNGRRLLRIEARNAQTPIEAKPRWIRTTATMGPEFRDMKKRVKGAGLHTVCQEAGCPNIHECWEDREATFLIGGDTCSRRCDFCDIKSGRPEPLDEDEPRRVAENVREIGLRYSTITGVTRDDLPDEGAWLYAEVVRQIHKLNPNTGVENLTPDFSGKPDLLQTVFEARPEVFAHNLETVPRIFKRIRPAFRYERSLDVIRQARDFGLVTKSNLILGMGETVDEVKSAMRDLRDAGCDILTVTQYLRPSNLHHPIERWVKPEEFVMYRDYGHDIGFAGVMAGPLVRSSYRAGRLYAQAIKARGEELPANLQHLGEGIDDTASQEASTLLSKYGASRETPVGAR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_ECO5E
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCEL_FOWPN
Sequence: MDKYISKTPLSCYFEELVDTFISVVNSINKVDESKHHEVELILFKPPIITLTNLYNMATTTESYIEFTMLPVDKPNTKFRNRIPLSKIHGLDVKNNQLVESLDGFIWEEKSLLLKKDISDNSSAIIKYSIEEKTLFVDYKRRNASIKLELVSVVRAKLRNIVIDFKMKYFLGSGAQSANSSSLLCALNHPKNKPSLYIEFEIMMQDKNISKKKLLEELNMSASALFLSHPKYIRLCPSINPILRTHLLKKQDIININTDDLYITSKTDGIFSHVYIEKKSIFCYFSHLGYIKEYTASREIEETIYLYAEMRKEESILYLTVIKVLKPCMEDRLSELAFVKNHLTGIHDRLVFVTKCYDGPFESSSDLVVSIEEMLKTEQEGIILFYSKGEDSTTDYKVKKDNTIDQCVNVIYRYMSSEPIVFNDKGSFLEYKRYSNDKGFPKEFSTGKLDLNGSVEYINNIYCIEIKHLNPCTGITNLVLPIKFIAEFSHNDELIQPRIDKTMKYLYESGYYGNQLSVIMDHLNDQKLRIGDVFEEEKLADIAAHMKLKDSMRLNPDGNYFLSNRVRGALGILSNFVKTLLISLYCSKTYLDNHSKRKVLAIDFGNGADLEKYFYGEIALMVATDPDDNAIETGKKRYNERNAGDKSKYYKFNYIKETIRSETYVSSIRQVLYFEKFSLVDWQFAIHYSFHPKHYSTIMTNLQELTESGCKVLITTMDGDYLDTLKEKKKFIIRKLLPETENYLSIEKIDDDKVLVYNPSSMSKPMAEYIVRRDTLIRVFREYKFKLIDSCNFKTIIDRNISFINGVSRLESRGSTKNFFELNRKALEECNDTDVLELLSHYMVYVFSKEV
What is the function of this protein?
The heterodimeric enzyme is also involved in early viral gene transcription termination and intermediate viral gene transcription initiation.  Early gene transcription termination requires the termination factor VTF, the DNA-dependent ATPase NPH-I and the Rap94 subunit of the viral RNA polymerase, as well as the presence of a specific termination motif.  Binds, together with RAP94, to the termination motif 5'-UUUUUNU-3' in the nascent early mRNA (By similarity).
What are the official names of this protein?
mRNA-capping enzyme catalytic subunit, Virus termination factor large subunit, VTF large subunit, mRNA-capping enzyme 97 kDa subunit, mRNA-capping enzyme large subunit.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.
Protein: NDUF4_HUMAN
Sequence: MGALVIRGIRNFNLENRAEREISKMKPSVAPRHPSTNSLLREQISLYPEVKGEIARKDEKLLSFLKDVYVDSKDPVSSLQVKAAETCQEPKEFRLPKDHHFDMINIKSIPKGKISIVEALTLLNNHKLFPETWTAEKIMQEYQLEQKDVNSLLKYFVTFEVEIFPPEDKKAIRSK
What is the function of this protein?
Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (PubMed:18179882, PubMed:28853723).  May be involved in cell proliferation and survival of hormone-dependent tumor cells.  May be a regulator of breast tumor cell invasion.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4, Hormone-regulated proliferation-associated protein of 20 kDa.
What is the protein family that this protein belongs to?
Belongs to the NDUFAF4 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Lipid-anchor.
Protein: HBB_ROUAE
Sequence: VHLSGEEKAAVTALWGKVKVEEVGGEALGRLLVVYPWTQRFFDSFGDLSSASAVMSNPKVKAHGKKVLDSFSEGLQHLDSLKGTFAKLSELHCDKLHVDPENFRLLGNVLVCVLARHFGKEFTPQVQAAYQKVVAGVATALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.