PharMolix/UniProtQA huggingface dataset:
Protein: S12A2_HUMAN
Sequence: MEPRPTAPSSGAPGLAGVGETPSAAALAAARVELPGTAVPSVPEDAAPASRDGGGVRDEGPAAAGDGLGRPLGPTPSQSRFQVDLVSENAGRAAAAAAAAAAAAAAAGAGAGAKQTPADGEASGESEPAKGSEEAKGRFRVNFVDPAASSSAEDSLSDAAGVGVDGPNVSFQNGGDTVLSEGSSLHSGGGGGSGHHQHYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKEPFEDGFANGEESTPTRDAVVTYTAESKGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLESKKPKGFFGYKSEIFNENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLNALQHSIRLSGVEDHVKNFRPQCLVMTGAPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELLSSQEKSPGTKDVVVSVEYSKKSDLDTSKPLSEKPITHKVEEEDGKTATQPLLKKESKGPIVPLNVADQKLLEASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIIAFEEIIEPYRLHEDDKEQDIADKMKEDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILLVRGNHQSVLTFYS
What is the function of this protein?
Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane (PubMed:32294086, PubMed:7629105).  Plays a vital role in the regulation of ionic balance and cell volume.
What are the official names of this protein?
Solute carrier family 12 member 2, Basolateral Na-K-Cl symporter, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein.
Protein: UL67_HCMVA
Sequence: MVRSLEEIIYIIYSDDSVVNISLASARCDGGPRRPLSRRGEEARRARAPSYEEQESSSFFHSKAHFFMWGRESMSFVYLHSVESYSLQFHDRCASYNDTFYPTNFTPIYIHTI
What are the official names of this protein?
Uncharacterized protein UL67.
Protein: TDX2_BRUMA
Sequence: MTLAGSKAFIGQPAPNFKTTAVVNGDFKEISLGQFKGKYVVLLFYPLDFTFVCPTEIIAFSDRIAEFKQLDVAVMACSTDSHFSHLAWVNTDRKMGGLGQMNIPILAYTNHVISRAYGVLKEDDGIAYRGLFIIDPKGILGQITINDLPVGRSVDETLRLIQAFQFVDKHGEVCPANWHPGSETIKPGVKESKAYFEKH
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
What are the official names of this protein?
Peroxiredoxin 2, Thiol-specific antioxidant protein 2, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2, Thioredoxin-dependent peroxiredoxin 2.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
Protein: ERG1_RAT
Sequence: MWTFLGIATFTYFYKKCGDVTLANKELLLCVLVFLSLGLVLSYRCRHRNGGLLGRHQSGSQFAAFSDILSALPLIGFFWAKSPPESEKKEQLESKRRRKEVNLSETTLTGAATSVSTSSVTDPEVIIIGSGVLGSALATVLSRDGRTVTVIERDLKEPDRILGECLQPGGYRVLRELGLGDTVESLNAHHIHGYVIHDCESRSEVQIPYPVSENNQVQSGVAFHHGKFIMSLRKAAMAEPNVKFIEGVVLRLLEEDDAVIGVQYKDKETGDTKELHAPLTVVADGLFSKFRKNLISNKVSVSSHFVGFIMKDAPQFKANFAELVLVDPSPVLIYQISPSETRVLVDIRGELPRNLREYMTEQIYPQIPDHLKESFLEACQNARLRTMPASFLPPSSVNKRGVLLLGDAYNLRHPLTGGGMTVALKDIKIWRQLLKDIPDLYDDAAIFQAKKSFFWSRKRSHSFVVNVLAQALYELFSATDDSLRQLRKACFLYFKLGGECLTGPVGLLSILSPDPLLLIRHFFSVAVYATYFCFKSEPWATKPRALFSSGAILYKACSIIFPLIYSEMKYLVH
What is the function of this protein?
Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
What are the official names of this protein?
Squalene monooxygenase, Squalene epoxidase, SE.
What is the protein family that this protein belongs to?
Belongs to the squalene monooxygenase family.
What are the subcellular locations of this protein?
Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: PEL2_ARATH
Sequence: MKIIRKDFVRNGPGSVKMMAEDSDDLWYTYNLIGPEDSVMAITFRKVGGEGRDSTPSLSRIESKYLGKKRSFTRTERVKLKLEVQVEEVDYDKDGDVMRIRGKNIMENEHVRIGAFHTLEIELKRPFLLRKENWDSLALDTLKQASDLAASADLAVVLMQEGLAQIFLAGKSVKSCGARIKTSIPWKHGAGTAGYESVLKKFFENVVQAFLKHVDFSVVRCAVIASPGFTKDQFHRHLLLEAERRQLRPILENKSRFILVHTNSGYKHSLSEVLHDPNVMNMIKDTKAAKEVKALNDFFTMFSNDPNRACYGPKHVEVAHERMAIQTLLIIDGLFRNSDVKTRKKYVDFVESVKDSGGEVFIFSSMHASGEQLAQHTGIAAILRFPLPDLEDIEM
What is the function of this protein?
Required for normal chromosome segregation during cell division and genomic stability (By similarity).  May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.  May have ribonuclease activity (Potential).
What are the official names of this protein?
Protein PELOTA 2, AtPelota2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: AROD_ECO24
Sequence: MKTVTVKDLVIGTGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLTATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: SOXR_PSEAE
Sequence: MKNSCASRELSVGELARRAGVAVSALHFYETKGLISSQRNAGNQRRFSRETLRRVVVIKVAQRVGIPLAEIARALQTLPAGRSPSAADWARLSAQWKEDLTERIDKLLLLRDQLDGCIGCGCLSLQACPLRNPGDQLSAEGPGAHWLDAEGREHDG
What is the function of this protein?
Activates the transcription of the soxS gene which itself controls the superoxide response regulon.  SoxR contains a 2Fe-2S iron-sulfur cluster that may act as a redox sensor system that recognizes superoxide.  The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity).
What are the official names of this protein?
Redox-sensitive transcriptional activator SoxR.
Protein: DAPB_ANADF
Sequence: MVNVVVTGAAGRMGTQIVRLVAAAEGLKLTGAVERPGHAGQDAGALAGIPPLGVAVVDDLAGALAGADVVIDFTSHEASARNAELCAEKGVALVIGSTGFTPEAKARVAAAAARIPVVFSPNMSVGVNVLFELVRQAAKVLGDAYDVEIVEIHHKRKRDAPSGTAVALGEVAAGALGRDPADALAYTRHGILGERPPWQIGVQTLRGGDVVGEHTVYFCGEGERLELTHRATSREQFARGAVRAAGFIAGKPAGLYDMADVLGLRSAR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_RICB8
Sequence: MNNNIVNLVAAIVLSLGIIFGWQYFIVKPQQQKQQQQIALQKAKDLKKKESAQLEATPVIVQEASQAPRIKIDSNALSGSISLKGLRFDDLILKKYKQDLSENSPEVVLFSPSDTKDAYFAEIGWVSNLSSVKLPNNETIWNSDSEILTPEKPVNLFWVNEDGVKFLVAITVDENYLFTIEQTIVNNSNQELPVQSYGLINRKYTAVEKAVNILHQGPIGCIDENLKEYSYDDIKDKKSEKFSASKVDWIGITDKYWLTSLIPDKSSNYSSNFNYAVKQEVERYQVDFISPVQIVKPGENFSIKGRLFAGAKKVDLLDKYEKQYDIKLFDRAIDFGWFYIITKPVFYAMNFFYKYVGNFGISILIVTVIIKLLMFTLANKSYRSMKRMKNLQPEINRIKNLYGDDKARLNQEIMALYKKEKVNPVAGCLPILVQIPVFFSIYKVLYVTIEMRQAPFYGWIKDLSAPDPTSIFNLFGLLHFSLPSFLMIGAWPILMAITMFLQQRMSPEPADPVQAQVMKFMPLVFLVMFSSFPAGLLIYWSWNNILSIIQQYYINKLDK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THY1_HUMAN
Sequence: MNLAISIALLLTVLQVSRGQKVTSLTACLVDQSLRLDCRHENTSSSPIQYEFSLTRETKKHVLFGTVGVPEHTYRSRTNFTSKYNMKVLYLSAFTSKDEGTYTCALHHSGHSPPISSQNVTVLRDKLVKCEGISLLAQNTSWLLLLLLSLSLLQATDFMSL
What is the function of this protein?
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
What are the official names of this protein?
Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: APT_BURP1
Sequence: MMSTSDAPLDPVEFIHSRIRTVPDWPQPGVMFRDITPLLQSAKALRVLVDLFVERYVDAKLDYIAGLDARGFIIAPIVAYELSVGFVPIRKVGKLPYATQRESYALEYGTATVEIHEDACKPGDRVVIVDDLIATGGTMMAGKNLLERLGAVVVEGAAIVDLPDLGGSALLRGAGLPLYTVTEFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_SHEB5
Sequence: MAITAAQVKELRDRTGAGMMDCKNALTETNGDMELAIDNMRKSGAAKAAKKAGNIAADGTILIKNGEGFAALLEVNCQTDFVAKDSNFLAFANAVLDAAAASKVTLEDLKAQFEDARVALVTKIGENINIRRVEYIDGANLSSYRHGERIGVVVAGEADEETLKHIAMHVAASKPEYVNPEDVPAEIVAREQALQIEMSMNEGKSAEIAEKMVLGRMKKFTGEISLTGQAYIMEPKKTVGEILKEKGAKVTNFIRLEVGEGIEKKEEDFAAEVAAQIAASKKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEP20_HUMAN
Sequence: MATVAELKAVLKDTLEKKGVLGHLKARIRAEVFNALDDDREPRPSLSHENLLINELIREYLEFNKYKYTASVLIAESGQPVVPLDRQFLIHELNAFEESKDNTIPLLYGILAHFLRGTKDGIQNAFLKGPSLQPSDPSLGRQPSRRKPMDDHLRKEEQKSTNIEDLHVSQAVNR
What is the function of this protein?
Involved in the biogenesis of cilia (PubMed:20551181).  Required for the recruitment of PLK1 to centrosomes and S phase progression (PubMed:24018379).
What are the official names of this protein?
Centrosomal protein 20, FGFR1OP N-terminal-like protein, FOP-related protein of 20 kDa, LisH domain-containing protein FOPNL.
What is the protein family that this protein belongs to?
Belongs to the CEP43 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic granule. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Localizes to the centrosome throughout cell cycle progression (PubMed:24018379). Localization to centrioles and pericentriolar satellites may be mediated by KIAA0753/OFIP (PubMed:26643951).
Protein: RR3_ACOCL
Sequence: MGQKINPLGFRLGATQSHLSLWFAQPKSYSMGLQEDEKIRECIKNYVQKNPRLSSGFEGIARIEIKKRIDLIQVIIYIGFPNLFIEGRTQGIKELQMSVQKRLNSVNQRLNIAIARISKPYGQPNILAEYIALQLKNRVSFRKAMKKAIELTEQADTKGIQIQIAGRIDGKEIARVEWIREGRVPLQTIRAKIDHCFHKVQTIYGVLGIKIWIFVDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VIAA_CITK8
Sequence: MLTLDTLNVMLAVSEEGIIEEIILTLLASPQLAIFFEKFPRLKRAISDDLPRWREALRSRLKDARVPPELTEEVMCYQQSQLLGTTQFIVQLPQILALLHRLHSPYAGQAQQLVDSNATFTPALHTLFLQRWRLSLIVQTTALNHQLLEEEREQLLSEVQERMTLSGQLEPVLAENDHAAGRLWDMSAGQLKRGDYQLIVKYGDFLAEQPELKRLAEQLGRSREAKSVPRKDAPMETFRTLVREPATVPEQVDGIQQSDDILRLLPPELATLGITELEYEFYRRLVEKQLLTYRLHGEAWREKVTERPVVHQDFDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALMRVALADNRRCFIMLFSTEVVRYELSGPEGIEQAIRFLSQRFRGGTDIASCFRAIIERMQGREWFDADAVVISDFIAQRLPDDVVNKVGELQRVHQHRFHAVAMSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: UPP_SHEB5
Sequence: MKVVEVKHPLVRHKIGLMREGDISTKRFRELAAEVGSLLTYEATADFETETVTIEGWNGPVEVDQIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFEKLASDMNERIALVVDPMLATGGSMIATVDLLKKRGCTSIKALVLVAAPEGIKALEAAHPDIELYTAAIDKCLNEKGYILPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: GAG_HV1Y2
Sequence: MGARASVLSAGELDKWEKIRLRPGGKKQYRLKHIVWASRELERFAVDPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQKIEVKDTKEALEKIEEEQNKSKKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRNQRKTVKCFNCGKEGHIAKNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSHKGRPGNFLQSRPEPTAPSEESVRFGEETTTPSQKQEPIDKELYPLASLRSLFGSDPSSQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: URE3_PSEPG
Sequence: MELTPREKDKLLLFTAALLAERRLARGLKLNYPEAVALISAAVLEGARDGRTVAELMSLGREVLTREQVMPGIAEMLHDVQVEATFPDGTKLVTVHDPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP_CLOB1
Sequence: MSMFCYQCQEAAGGRGCTVKGVCGKTEDIAKTQDLIIYVVKGIAIYSSQVREIGLNTSEADKFIVESLFSTITNANFDAKALNARVQEGLKIRQSLKDAIIKAGGSYNSKENKSWTSKFLSVLGIKNDKDEKEIHDAAAWAANNPEDFKKKAETVGILATENEDIRSLRELLTYGLKGMAAYLEHANNLGYDEDSIHAFMEKALVATLDDTLSADELTALVLECGKYGVDVMALLDKANTSTYGNPEITKVNIGVRNNPGILISGHDLKDMEELLKQTEGTGVDVYTHSEMLPANYYPAFKKYKHFVGNYGNAWWKQNEEFEAFNGPILMTTNCIVTPKASYKDRMYTTGVTGFEGVKHINASKDGKKDFSEIIEHAKRCSSPKEIEKGEIIGGFAHNQVLALAPQVVDAVKTGAIKRFFVMAGCDGRMKSRNYYTDFAKALPKDTVILTAGCAKYKYNKLDLGDINGIPRVLDAGQCNDSYSLAVIALKLKEVFELEDINELPISYNIAWYEQKAVIVLLALLHLGVKNIHLGPTLPAFLSPNVAKILVENFGIGTISSVDKDIKMFMN
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NP7_HUMAN
Sequence: MNPLEMQRKGPPRRWCLQVYPTAPKRQRPSRTGHDDDGGFVEKKRGKCGEKQERSDCYCVCVERSRHGRLHFVMC
What is the function of this protein?
May possess a function in tumorigenesis.
What are the official names of this protein?
Endogenous retrovirus group K member 7 Np9 protein, HERV-K(III) Np9 protein, HERV-K102 Np9 protein, HERV-K_1q22 provirus Np9 protein.
What are the subcellular locations of this protein?
Nucleus. Note=When overexpressed.
Protein: DAPB_SYNWW
Sequence: MKQKARVIVAGALGKMGKETLKAIAGDEELELIAAVDIKAKGEKVADLIGIAGLDISLENDLDEVLENYQPDVLVDFTNPQAVFNNARSALKIGVFCVIGTTGLNEIEIKELEKLAGEKQVGVAIIPNFAIGAVLMMKFASEAAKYFPEVEIIELHHDQKMDAPSGTAIKTAEMINANRPLRPPRNVREFEKIAGCRGGDLGQVRIHSVRLPGLIAHQEVIFGGAGQGLKIRHDSFDRAGFMPGVVMVIKKILQRKELVYGMENLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRC1_YEAST
Sequence: MDDALHALSSLTAKKRTTTYKKVAVPILDENDNTNGNGPNDIDNPPELTGNGFLFANATLNRVKNRLEGKKAPEQNHNNGKDRSENSLPTQLISNLYDGGEELEKSEVKDNSYSEKNVSSSFTQTQRIPVSIQQDKVFNVPIHSVNDGKPTQLIKEDGLVNETSQALKTPLTTGRPGATQRIDSSGATSQTQPIKSIEPQSQIITTSSNHSNALSPKIPIIPTELIGTSPLFQSIQNRGPDTQMDVPPQTAHDEDKTQAIGIPQATHQEQKTQIDTVAQTLQDEVPHTLKIREIQSELASEDSKREKARNVEYKKPQKPIPTKKFFSKESFLADFDDSSSNEDDDIKLENAHPKPVQNDDELHENKSVELNLTDETRINEKRVPLLSSYANNLKREIDSSKCITLDLDSDSDEYGDDDMDSIKLSKDESVLPISQLSKATILNLKARLSKQNQKLSQRPNKSKDPKVDHNVLLNTLRKASRKQILDHQKEVIETKGLKLEDMAKEKEIVENLLEQEILRNKRIRQKEKRREKLEENDFQLNAHDSGSDSGSESSGFALSGNEIADYESSGSENDNRRESDSEKEDDEIILKQKKSHHVKHIINESDSDTEVEAKPKEKADESLPKRIAINLGHYGDNIGEDTDKFQETNVLDTQNIEEVMAERNTIENEVKDDVYVNEEADEAIRRQLIDKEKLQLKQKEKEHEAKIKELKKRGVTNFFEMEAEESEDEWHGIGGADGEGSDDYDSDLEKMIDDYSKNNFNPHEIREMLAAENKEMDIKMINKILYDIKNGGFRNKRAKNSLELELSDDDEDDVLQQYRLKRRELMRKRRLEIGDDAKLVKNPKSSAFFESMVEDIIEYKNPFGAEEEYNLDITSTATDLDTQDNSINVGDNTGNNEQKPVDQKNKKVIISEDFVQKSLSFLKSNNYEDFETDKELSRIQHGNDEAIEDLYTLKQNSSIKSFTNSQTDSTTSKTVNTIIDLEKRPEDEDEVENGDTSLVGVFKHPSIIKSFASRTDINDKFKEGNKTVKILKSYKTVGSSKASITYMGKTRKLIAPKRKTEGSHRYHHDHHNKKMKMKTKTKSNKLFESGQDSFDN
What is the function of this protein?
Required for normal DNA replication.  Phosphorylated in response to DNA replication stress.  Phosphorylation allows it to mediate the activation of RAD53.
What are the official names of this protein?
Mediator of replication checkpoint protein 1, DNA replication checkpoint mediator MRC1.
What are the subcellular locations of this protein?
Nucleus. Note=Associated with chromatin during S phase.
Protein: NICD_PSEPK
Sequence: MSTFVAGGNVSANGIRQHYLRYGGKGHALILVPGITSPAITWGFVAERLGHYFDTYVLDVRGRGLSSSGPDLDYGTDACAADIPAFAAALGLDSYHLLGHSMGARFAIRAAAQGAPGLQRLVLVDPPVSGPGRRAYPSKLPWYVDSIRQATVGMSGDDMRAFCATWSDEQLALRAEWLHTCYEPAIVRAFDDFHEVDIHQYLPAVRQPALLMVAGRGGVIEPRDIAEMRELKPDIQVAYVDNAGHMIPWDDLDGFFAAFGDFLDHPLV
What is the function of this protein?
Deformylase that catalyzes the conversion of N-formylmaleamic acid to maleamate in the aerobic nicotinate degradation pathway.
What are the official names of this protein?
N-formylmaleamate deformylase, Nicotinate degradation protein D.
Protein: RPOB_RHOOB
Sequence: MLEGRILAVSSQTKAVSGIPGAPKRVSFAKIREPLEVPGLLDLQTDSFEWLIGAQSWRERAAARGDSAISGGLEDILAELSPIEDFSGSMSLSFSDPRFDEVKASTDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTDKGTFIINGTERVVVSQLVRSPGVYFDHSVDKGTEKDLHSVKVIPGRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTTEQIAERFGFSEILMATLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKDKRYDLARVGRYKINKKLGLNTGQPIVASTLTEEDIVATIEYLVRLHAGDTEMTAPGGVAVPVEVDDIDHFGNRRLRTVGELIQNQIRVGLSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVEGGQVTDQVDYLTADEEDRHVVAQANSAVDANGHFTDDRILVRRKGGEVEFVSSAEIDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAVDAGDVIVTEKTGVVEEVSADYVTVMADDGSRKTYRMRKFARSNQGTCANQRPIVDEGQRVESGQVLADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSQRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIIRIGAEVRDGDVLVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGETGKVIGIRVFSRDDDDDLPPGVNELVRVYVAQKRKIQDGDKLAGRHGNKGVIGKILPQEDMPFLPDGTPIDIILNTHGVPRRMNIGQILETHLGWIGKTGWNVQIAGDGSRPDWAEQLPEEMLSAPSDSNIATPVFDGAKEDELTGLLGSTLPNRDGEVMVASDGKATLFDGRSGEPFPYPVSVGYMYIIKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDVVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSSDGAAIAMADGDDEDLERAAANLGINLSRNEAATVDDLAN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MSCL_SALNS
Sequence: MSFIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAFTLREAQGDIPAVVMHYGVFIQNVFDFVIVAFAIFVAIKLINRLNRKKAEEPAAPPAPSKEEVLLGEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PATA2_SOLTU
Sequence: MATTKSFLILIVMILATTSSTFASLEEMVTVLSIDGGGIKGIIPGTILEFLEGQLQKMDNNADARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAANEIVPFYFEHGPHIFNSSTGQFFGPKYDGKYLMQVLQEKLGETRVHQALTEVAISSFDIKTNKPVIFTKSNLAKSPELDAKMYDICYSAAAAPTYFPPHYFATNTINGDKYEFNLVDGAVATVADPALLSVSVATRRAQEDPAFASIRSLNYKKMLLLSLGTGTTSEFDKTHTAEETAKWGALQWMLVIQQMTEAASSYMTDYYLSTVFQDLHSQNNYLRVQENALTGTTTKADDASEANMELLAQVGENLLKKPVSKDNPETYEEALKRFAKLLSDRKKLRANKASY
What is the function of this protein?
Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens.
What are the official names of this protein?
Patatin group A-2.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Vacuole.
Protein: RBFA_SALTO
Sequence: MSDPAKVRRHAERVRELVASVVRSQIKDPRLGMITITDARITADLRDATVFYTVLGDASAQASTAAALESAKGMVRSTVGKALGLRHSPTLTFVLDDVQDQVKHIDDLLAQARHADAEVQRLATRAEYAGEAQPYRLEEEPEGSGDEVPPPGGDQR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.