PharMolix/UniProtQA huggingface dataset:
Protein: KAD_METPB
Sequence: MRIILLGPPGAGKGTQSERIVERYRVPQLSTGDMLRAAVAAGTPVGLEAKSIMESGGLVPDAVVVGIVADRIEEADARDGFILDGFPRTVEQAKALDAMLAEKGIALDAVVEFVVDENALVGRIAKRAEETAARGQPVRKDDTPEVFKTRLDAYKRQTAPLSDYYAGTGLLRKIDGMKPIDEVTGDVTGLLDGFREKATS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGFB3_HUMAN
Sequence: MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
What is the function of this protein?
Transforming growth factor beta-3: Multifunctional protein that regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development (By similarity).  Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains remain non-covalently linked rendering TGF-beta-3 inactive during storage in extracellular matrix (By similarity).  At the same time, LAP chain interacts with 'milieu molecules', such as LTBP1 and LRRC32/GARP that control activation of TGF-beta-3 and maintain it in a latent state during storage in extracellular milieus (By similarity).  TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3 (By similarity).  Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal (By similarity).
What are the official names of this protein?
Transforming growth factor beta-3 proprotein.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix. SUBCELLULAR LOCATION: [Transforming growth factor beta-3]: Secreted.
Protein: CXA4_MOUSE
Sequence: MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLIYLGHVIYLSRREERLRQKEGELRALPSKDLHVERALAAIEHQMAKISVAEDGRLRIRGALMGTYVVSVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPHIVDCYVSRPTEKTIFIIFMLVVGVISLVLNLLELVHLLCRCVSREIKARRDHDARPAQGSASDPYPEQVFFYLPMGEGPSSPPCPTYNGLSSTEQNWANLTTEERLTSSRPPPFVNTAPQGGRKSPSRPNSSASKKQYV
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction alpha-4 protein, Connexin-37, Cx37.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: END4_HALMA
Sequence: MVRVGAHTSIAGGVYNAVEEQVEYSGNCGQIFSHSPQVWQDPNIDDDEAEQFRDLAADHGVGPWVIHSSYLVNLCTPKDDLREKSLDSMQKEVDAAAKLGIEYVNVHLGAHTGAGVDGGLDNAASVLDDLDIPEGVTVLVESDAGSGTKLGGQFEHLATVRERTDQDIEFCLDTAHMFAAGYDLSTPEAVDETLAEFDEVVGVEDLACVHLNDSKHECGTNKDEHAHIGEGHIGEDGMRAFVNHDAIRDVPLVLETPTENGKSFAWNIERVKELRGE
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: SYE_SYNR3
Sequence: MVRVRLAPSPTGTLHIGTARTAVFNWLYARRHGGEFVLRIEDTDKERSKSEYTSNILDGLKWLGIDWDAEPVIQSERVEQHRQAIQQLLDAGLAYRCYASEEELNAMREAQMANKKAPRYDNRHRNLSHEQEADYQAEGRQATVRFRIDDSRNIQWNDLVRGAMSWSGADLGGDMVIARRAPADQIGDPLYNLVVVVDDAAMAITHVIRGEDHIANTAKQLLLYEALGLPLPEFAHTPLILNQEGRKLSKRDGVTSVSDFRGMGYTASALANYMTLLGWSPPEGMGERFSLAEAAKVFDFQRVNKAGARFDWDKLNWLNGQVLHELGAAELNRKLTPLWQEAGFETSGRSQAWLEQLCELLGPSLTLLADGVEQARPFFETPSLKEDAQQQLQQPGAKEALKALLSSLSDEPLQAEQAKALISDACKAADVKKGVLMKSLRGALMGQLQGPDLMESWLLLNAAGQDRGRISSALG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_STAEQ
Sequence: MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDGTKLFKEKGRIAELRKVADNSDEDGTLGIGHTRWATHGVPNYENSHPHQSTSGRFTLVHNGVIENYEELKAEYLSDVTFSSETDTEVIVQLVDYFSRQGLATEDAFTKVVKLLHGSYALGLLDDNDKDTIYVAKNKSPLLVGVGEGFNVIASDALAMLQTTNQYKEIHDHEIVIVKRDTVEIKDLEGHIQQRDTYTAEIDAADAEKGVYDHYMLKEIHEQPAVMRRIIQEYQDEKGNLKIDSEIINDVADADRIYIVAAGTSYHAGLVGKEFIEKWAGVPTEVHVASEFVYNMPLLSEKPLFIYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKNHGRETDVDLLRELAKVTTAIETIVDDAPKMEQIATDFLKTTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVIGLATQENVNLSIRGNMKEVVARGAYPCMISMEGLNKEGDTYVIPQVHELLTPLVSVVTMQLISYYAALQRDLDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_SERP5
Sequence: MDEKRLTHLRQLEAESIHIIREVAAEFGNPVMLYSIGKDSSVMLHLARKAFFPGTLPFPLLHVDTGWKFSEMYQFRDRTAKEYGFELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTELDIWQYIFLEKIDIIPLYLAKPRPVVERDGMLLMVDDDRIDLQPGEVISQRMVRFRTLGCWPLTGAVESEAQTLPEIIEEMLVSTTSERQGRMIDRDQSGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: TXGBA_ETHRU
Sequence: MKSWTAAVLSLGLIYLSISQNEGATTEFPTMNYEGRCALDMFTLIEVGDTFNYRHACLSYTCMKRDETFYVQVHTCDAPHFENVTSGMICNFTPPTTGNFPDCCLKVNCIAHLNHTSAN
What are the official names of this protein?
U-scoloptoxin(16)-Er11a, U-SLPTX(16)-Er11a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMK_IDILO
Sequence: MRIAILSRNASLYSTRRLVEAAEERGHEVDVLNPLRCYMNINARESSIHKHGKELPHYDCVIPRIGASVTFYGTAVLRQFEMIGSYPLNESVAISRSRDKLRSLQLLSRKGIGLPTTGFASQPQDIPDLIDMVGGAPLVIKLLEGTQGIGVVLAETRQAAESVIEAFMGLHSNFMVQEYIKEAGGADIRCLVIGDKVIAAMKRQAKAGEFRSNLHRGGSASLVKLTPAERATAVKAAKTMGLNVAGVDILRSNHGPLVMEVNSSPGLEGIEQATEKDVASQIITFLEKNAKAHKTRTKGQG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: NUCS_SULIY
Sequence: MYSVLLNPSNTEIYSFLTERIYRELVVIFATCKVNYKGRAESVASESPRLIILKPDGTVIIHESVKREPLNWQPPGTKIEIMNDYPLKIVAQRKRPKEVIEIDLKEVFYITSAEVKDGDFVIKGREIDIVNTIIQNPSMIEEGFVPLTREYNTPYGKIDLVGLDKKGNFVIIEVKRSKAQLSAVSQLYRYYLHIRETKEDKVRGILVAPDLTTHARELLQKLGLEFIRYDIQKYSSY
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_MAGMM
Sequence: MEYPTPLTPARMVQRYKRFLSDVTLADGTQVTAHCANSGSMRGLVHVGEPVYLSHSDNPKRKLAWTLELVCDGGALVGVNTGLANALVAEALQQDRIPPLQGFAHFRREVPYQDSRLDFCLTAPAGALTYVEVKSVTLRLTDEAAFPDAVTKRGAKHLAALRHAVKAGHRGVILFIVQRSDLDHFRPAHEIDPGYAQTLQWAISEGVEILVYACALTTASIYVERPLSYTLG
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RL20_RHOJR
Sequence: MARVKRAVNAQKKRRSILEASSGYRGQRSRLYRKAKEQQLHSLTYAYRDRRARKGDFRKLWITRINAAARANDITYNRLIQGLRLAEIEVDRKNLAELAVSDAAAFAGLVALAKAALPADVNAPAGEAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NPC2_YARLI
Sequence: MKLSILPLIALATAVVASPAPDANSMKLMNQAKDFGMSVAQGGLKDIAKTLDDEDIPGDSPISLCDAEYEQLLEIKHLSIDPNPPAKGQNLTIEASGYLYEDVEEGAYIEVEVRYGYIRLISQTLDLCEQSEQVDWSCPIKAGDLKLNKQIELPNEIPPGKYVAVARAYTVDDDLITCLLTTVTFPASL
What is the function of this protein?
Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
What are the official names of this protein?
Phosphatidylglycerol/phosphatidylinositol transfer protein, PG/PI-TP.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
Protein: RN169_DANRE
Sequence: MKMAAVGSAKSTGPGQRSKSRPGALSAPLSLEEARCPVCSEILLEPVTMPCGHSVCLHCFQRTVKLISLCCPLCRLRVSSWARKQSREKSLVNAELWELVRLSHPERCKRRMEQRDGEIPDGEIFRAPVPVHKVGEMRQEYEKQKMKSGRSEETDERKKKMHIKEECVLLKHCQYPFCGVSDSENEEPVGRRTRHVSAFVRKTRCSPAFNKSCLHSSAAQRSRSCTDSEDGRGKSRGHTNQAVPEKANIAHSYNAGILLSSENSRSFSAPLLSLDKRHHWRGIHTSSATLVLQTKPERSISPESNDSISEELNHFKPIVCSPCTPPKRLPDGRLLEPMIVKSTPRNLTRALHKSTSYEASPTILQKWKQIEVDRQCIKVTSKGTVTSPIAEDLNLKLSPVEERDCQPCSCSVAKDRLLDLQCICGSNAHKSKSRKDKPIIYNKRRLIFDPYNKGEEKTQVAALIKTFGDSSTPKACKELCEPSEMGPPMLDSNAGHCNQGTVDPDHNIKINEPTTMSCVLNRPTSRRGKKRSQKTKHMEETLQTKISRTNRYDSLDDLIVQRMSQEKEDRELALKLQRQFDRECKKVDRHKTSRNKYELRSWGSKDGIVGYNTRRSGRVSKQNEHFNYTC
What is the function of this protein?
Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF169, RING finger protein 169, RING-type E3 ubiquitin transferase RNF169.
What is the protein family that this protein belongs to?
Belongs to the RNF169 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Localizes to sites of double-strand breaks (DSBs) following DNA damage.
Protein: LOLD_BACFR
Sequence: MIHLEGITKSFGSLQVLKGIDLEITQGEVVSIVGPSGAGKTTLLQIMGTLDSPDTGMINIDGTNVSRMKEKELSAFRNKHIGFVFQFHQLLPEFTALENVMIPAFIAGVPTKEASMRAMEILDFMGLKERASHKPNELSGGEKQRVAVARALINQPAVILADEPSGSLDSHNKEELHQLFFDLRNRFGQTFVIVTHDEALAKITDRTIHMVDGNII
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YPI1_LODEL
Sequence: MPQQTQTQVETSTSSSSLSQTQTEQQSGPSPPQDQQVQGVLRLRPDSATDTKNKNKSKKKKPKVRWTEDVVDNEHMNKKKTKICCIFHPQRSFDDEMAEHNHEHDHGHCDSSDSDSSSDLSSDESEEENGNKLPSNGRGSDKDKLYKPNSYEYQPHYENKSRVQL
What is the function of this protein?
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
What are the official names of this protein?
Type 1 phosphatases regulator YPI1.
What is the protein family that this protein belongs to?
Belongs to the YPI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PETD_JASNU
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HIP47_ARATH
Sequence: MRIKLSVNSEKCRKKAMQVAVAADGVTSVAMEGEFQDELVVVGDGVDSASLIMALRKKACHVTLETLEEVKKPQVEEKSITPHCCIAQCPVVSNEQPRPEVYRIVHDSYGPTTGCLVM
What is the function of this protein?
Heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 47, AtHIP47.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: Y864_CALS8
Sequence: MADRIYDYKREKTKRVVKKVGFVISILVILAIVFSIAFDLFLELIQIKEIGRNFVSVFWKNFYVKLSVQVVSFMILFFVFFVNNAVIKRNIERIVGKISLLKKNILNVIVSVLLALIASRYLENNLYIKFLTFKHSKPFNIKDPIFNKDVGYYVFERPFFLSIVNFLFYLVIFVCIYTVVLYIVLYGFAFVSRVNSWGVLYDKKVRSHIFFNLILIFVIKIFTLKYEMEGLLYSFFGEVVGVGYTDYYIRMNYFRLSYIVLVAVILLSIYFFIKGKYANIAKVMLSYIGWAVLGTIIATAFQYFVVSPNEQVYERSFLEKNIKFTRLAYNLENIEEKYFPVDTSGTITAEDLQKNTGTIENIRITDYPTTLAILNQIQRFKQYYIFNDADIAKYTINGKIKSVFISAREINYDGIPTKTYINQKFQYTHGYGVVMSLMTEVTPEGQPKFIIKDIPLKSLDGAPKVTQPRIYYGEKTDPYVIVNTKVDEIDYPEGDSNRLFRYDGKGGIRLTPLNRLIFSYVYKDFRLLVSTAINSNSKILINRSIIERAKKVAPFFDYDTDPYILIDGKGHLVWVLDGYTKTNYYPYSEPTEEGFNYIRNSVKVLIDAYNGTLKFYIVDKNDPIVNVYKSIYPDLFENGDIPRDIAEHIRYPEYIFKVQASVLKRYHMTNPNVFYNKEDLWDFGKHKTPDGSIDYIPPYYSVMKLPDSQKEEMILMVPFTPLKYNTMIAWLAAKSSQENYGKLVLYKFPKGSTVYSPLQVENMIDQDPQISKDLSLWNQGGSKVIRGNLLALPINQKILYIEPIYIASDNASALPEVKRVIAACNGKVVMGSSLNDALSQLVGQQVTPVKDQMQTPSQKENITQVLPSSDLLKIKSLFEDAKKALQQGNWEEFGKKFKELDDMMKNVK
What are the official names of this protein?
UPF0182 protein Csac_0864.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF1_ONYPE
Sequence: MSKNNLNETESKIEIEAKVVELLSNDKFKVELPNKKTIIAYVSGKIRINNIRILPGDKVRIELSPYDPTRARITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADA2_PONAB
Sequence: MLVDGPSEWPALRFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEEQANERLMMLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVTMDWLVRNVTYRPHCHICFTPKGIMQFRFAHPTPRTSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFQSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRTAMGLRTKFPTVVAGFDLVGREDTGHSLQDYKEALMIPAKGGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRAYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAIFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSALLEIEKNTFMEIWKKRWDKFIADVATK
What is the function of this protein?
Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses.  Requires elevated adenosine levels for optimal enzyme activity.  Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity (By similarity).
What are the official names of this protein?
Adenosine deaminase 2, Cat eye syndrome critical region protein 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SMD3_SCHPO
Sequence: MSLCIKLLHETQGHIVTMELENGSTYRGKLIEAEDNMNCQMRDISVTARDGRVSHLDQVYIRGSHIRFLIVPDMLRNAPMFKVGPGRSVPLPTRGRR
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
What are the official names of this protein?
Small nuclear ribonucleoprotein Sm D3, Sm-D3, snRNP core protein D3.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: DAPE_CROS8
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAVGFTVEPMNIGDTQNFWAWRGTGETLAFAGHTDVVPAGDVERWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPHHRGRLAFLITSDEEASATNGTVKVVEALMARGERLDYCLVGEPSSSEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPMLNELVGIEWDRGNEFFPPTSMQIANIQAGTGSNNVIPGDLHVQFNFRFSTELTDEMIKQRVVALLEKYQLRYTLDWWLSGQPFLTARGKLVDAVVNAVHHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVKASDLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: ILVC_PARMW
Sequence: MAQLFYDSDADLGLLNSKTVAIIGYGSQGHAHALNLKDSGVNVVVGLYDGSRSADKAKADGLEVLSVADASAKADWVMVLLPDEFQKDVYEKEIAPHLTSGKVLSFAHGFNIRFELIKPPTDVDVVMIAPKGPGHTVRWEYQNGQGVPALFAIEQDASGQARGLAMAYAKGIGGTRAGILETNFKEETETDLFGEQAVLCGGLSELVKAGFETLVEAGYQPELAYFECLHEVKLIVDLMVKGGLTSMRDSISNTAEYGDYVSGPRLITADTKAEMKRVLADIQDGTFAKNFVAECEAGKPEMKKVRDRDSQHPIEKVGKGLRSMFSWLKDA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: Y1661_MYCLE
Sequence: MYRVFEALDELGAIVEEARGVPMTAGCVVPRGDVLELIDDIKDAIPGELDDAQDVLDARDAMLNDAKAHADSMVSSATTESESLLSHARAEADRILSDAKSQVDRMASEARQHSERMLGDAREESIRIATVAKREYEASLNRAQSECDRLIENGNISYEKAIQEGIKEQQRLVSQNEVVQAANAESTRLIDTAHAEADRLRGECDIYVDNKLAEFEEFLNGTLRSVGRGRHQLRTAAGTHDYVTR
What are the official names of this protein?
Uncharacterized protein ML1661.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2927c.
Protein: Y1176_BACC2
Sequence: MEYQYPLDYDWSNEEMVTIVKFYEAIEKAYEKGIIREELMGLYRRFKEIVPSKAEEKKIDKEFQEVSGYSIYRAIQRAKEVEEQKVVKI
What are the official names of this protein?
UPF0223 protein BCG9842_B1176.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: IP6K2_RAT
Sequence: MSPAFRTMDVEPRTKGILLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRRFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGPVDIVDNSDCEPKSKLLRWTNKKHHVLETEKSPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYSVEKKGTVSSQLKHYNPWSMKCHQQQLQRMKENAKHRNQYKFILLENLTCRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGTGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLRRELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKEWPEVTLDSDAEDLEDLSEESADESAGAYAYKPLGASSVDVRMIDFAHTTCRLYGEDSVVHEGQDAGYIFGLQSLIDIVTEISEESGE
What is the function of this protein?
Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5).
What are the official names of this protein?
Inositol hexakisphosphate kinase 2, InsP6 kinase 2, P(i)-uptake stimulator, PiUS.
What is the protein family that this protein belongs to?
Belongs to the inositol phosphokinase (IPK) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KATG2_SHEFN
Sequence: MKHPLFNQKVLAGFVSMLLISGSAFASNNEKSEMTKPKGAVGTGVALENQARTNQFWWPDQLNLSALRDHDKRSNPYGENFDYAKAFNSLDLDKVKLDINALLTTSQDWWPSDYSNYGPFFIRMTWHSAGTYRTLDGRGGAGGGQQRFEPLNSWPDNASLDKARRLLWPIKMKYGEAISWSDLIVLAGNVSLENMGFKTYGFAGGRHDDWEPDMVYWGPEIEMLASDREDNGGKLQRPLGATHMGLIYVNPEGPKGVPDPLGSAKNIRVAFERMAMNDEETLALIAGGHTFGKMHGAHKPKDCLGAEPAAAGIEEQGLGWKNKCGKGHSEDTITSGLEGAWTQAPTKWTSLYLSNLLTFEWKQTRSPAGAIQWIPTDESLHKAVPDAHVKGKFHAPVMTTADLALKYDPEYRKIAERFLADPEEYRLAFAKAWYKLTHRDMGPSRNFLGKEVPKESLIWQDPIDDKTQSNIDADGVQELKAQILKSNLTVSELVRVAWASAASYRHSDMRGGANGARIALSPQKDWSVNNPAETAKVIKTLKAIQEDYNDSLFSKSKVSLADLIVLGGTAAIEKAAKDAGFTVSVPFNAGRGDATQAMTDINAFSLLELTSDGFRNYFDAQQSYKSPVDMLVDKADQLNLSVPEMTVLVGGLRALDANYKGLKHGVLTSTPGTLNNDFFVNLLDMSTVWKKSSTDGIYEGFDRQSGHKKWTATSVDLVFGSNSELRAVSEVYAFDTSKQKFVEDFAAAWTKVMNLDR
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 2, CP 2, Peroxidase/catalase 2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: TRM14_METJA
Sequence: MDYYVTLSPGLEKISKNEIESFGGKIKEIRENKGRIFFSGDLKLIPKINYLSRTIERMNILLHREEIPNIALDDIYKRVYNIDWTEWIKENQSFAIRPLRAGEHNFTSIDIGRVAGEAVIKSYQRDKNIRLKVNLDEPDVIVRVEVIFDELIVGIDTTGDIALDKRGYRVFNHPAHLNATIASSLVYLSDWKDDEMLLDPMCGSGTIPIEGALMKRNIPPGKFRENKYGFKFIDIFGYELLDKIKKEIVENKNIYKIIGLDKNQKYLDGAKDNAKNAEVLDTIEFICGDATKLHEKFNESDVIIANPPYGIRIGSKRSVKKLYDEFLSSAKEIMHGSSRLIVITAEDKMFKDAIAKNNFEVKEEFNVMFGGLMTRVFYLTL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the methylation of the guanosine nucleotide at position 6 (m2G6) in tRNA(Cys).
What are the official names of this protein?
tRNA (guanine(6)-N2)-methyltransferase, tRNA m2G6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.