PharMolix/UniProtQA huggingface dataset:
Protein: SYC_STAXY
Sequence: MITLYNTLTRQKETFEPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYEVIYVSNFTDVDDKLIKRSKELDESVETITDRYIKAFYEDVGALNVKKATSNPRVMNHM
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDS23_PHANO
Sequence: MADHADATKKDGRIPSPLHSLASSTASLGRSPPPALKMASSPDPRSHRGSFAEQMRGTPSSPRASRQPSLTQSALQELLNNPPTKGGDAKFQSRDWSSVRLGELVDPSLVRFVEYDTSVEDATSILVQHGAPNVILLRDTKDTRYATGTFDYSDLNAYLLLVVGLAHPDEEDVASFDELAKKGREGKPIPLRDVKEVGNKKEPLITLPHTADLTKAIEVFGSGVHRVLVAEEGTTDVIGVLTQLQLVKFFWENRQSFPDVDQLYPRLIKDLAIGSKTVLAINGDKPLASALELMNNEGVSSLPVLDAQNNVIGNISHVDVRLLTKSTSLPLLRSSCIHFISVILSERGMNDGKDSFPVFHVNPYSTLAHTVAKLVATRSHRMWVVDSPSPSSSGPPTPALQPASLVPPSPITPLPATHIGPTPVNSTSPTHLAGTGAVAPAISASAISGASLSGRLSGVISLTDVLNLFAKASGLHPHDPDEARRARRRSSSSSMRRSMDSARSESVSAIAGRRGSVNEREKNVQGLGIARGRGNA
What is the function of this protein?
Involved in DNA replication and cell separation.
What are the official names of this protein?
Protein SDS23.
What is the protein family that this protein belongs to?
Belongs to the SDS23 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: E2AK1_SCHPO
Sequence: MLGTSTKCSKRDCNYAKENISRIMPTIGLGYKQNFEKKTADTQSSCKLLLVALLESFCKHSDQTPEQSKQMFLYVAHSLQNSGIIDFEFSEELEPIRNAYADSLHNLLSKAFRSTLPMSSTKDSKKSRYSSPDGVLAKTASFLSVLSDGGYEDDVMNVKPSVNVLSNRLNHLPVEALESCFPQTTLESSTFADFCEHKDGTGNLSFSNFDSFPTVQRSRYASDFEELELLGKGGYGSVYKARNKFDGVEYALKKIPLRLRSFSTSSNIFRESRTLARLNHPNVIRFFSSWVELLPSSEKQIEEEPLASADETLSQSADIDNFMFDMDTGLLQHTYPSSVQILFQEDSVADDLTPCYSTKNSTCNLTDLFKKEADQDYAESHDCSSTTSQVDTLGKLAPTKSASEMLLMDSFLSEREEDECSNIPSFDQQPLCLYIQMALCEETLEKHINRRNKHIHGVMSKGLRNCYILLFARILEGVLYLHDAMHLVHRDLKPRNIFLSSGVHSEPCSVCLPNFSDEDNVEVSNAYEPVNQRTLCVVPKIGDFGLVLSQSDNLEEGTNSSAESSFVGTSTYAAPELFSKHMRSVMNNNSSTDIYALGILFFELLYPFNTRMERASAIANLKKGIFPHDFLDSMPEEASLIRSMLSSSNKRPTAAQLLTSNLFHDLVVNELHVYQALLEDAEKRNNNLKAELNILRVLNPNYDC
What is the function of this protein?
Mediates down-regulation of protein synthesis in response to stress conditions by the phosphorylation of the alpha subunit of eIF-2 (tif211) on 'Ser-52'.  Protein synthesis is inhibited at the level of initiation.  Activity is inhibited in the presence of heme.
What are the official names of this protein?
Eukaryotic translation initiation factor 2-alpha kinase 1, Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase, Heme-regulated inhibitor 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
Protein: RS4_BUCAP
Sequence: MARYLGPKLKLSRREGTDLFLKSGFRSIDSKCKLEHPPGQHGVRKPRLSDYAIQLREKQKVRRLYGVLERQFRIYYKKASRSKGNTGENLLQLLERRLDNVVYRMGFGCTRSESRQLISHKSIKVNNNIVNIASYQISPNDRISVRDKSKNQSRIKAALELTEQREKLMWIEVNVTKMEGIFKRFPERSDLSAEINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TRHO_PSEU2
Sequence: MTQPIVVAALYKFVTLSDYVELREPLLQAMVDNGIKGTLLIADEGINGTVSGSREGIDGLMAWLKSDPRLIDIDHKESYCDEQPFYRTKVKLKKEIVTLGVEGVDPNKSVGTYVEPKDWNDLISDPEVLLIDTRNDYEVSIGTFEGAIDPKTTSFREFPEYIKAHFDPAVHKKVAMFCTGGIRCEKASSYMLGEGFEEVYHLKGGILKYLEEVPEQESHWRGECFVFDNRVTVRHDLTEGDYDQCHACRTPISAEDRASEHYSPGVSCPHCWDSLSEKTRRSAIDRQKQIELAKARNQPHPIGRNYRLPSEA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: CP1A2_HUMAN
Sequence: MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins (PubMed:9435160, PubMed:10681376, PubMed:11555828, PubMed:12865317, PubMed:19965576).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:9435160, PubMed:10681376, PubMed:11555828, PubMed:12865317, PubMed:19965576).  Catalyzes the hydroxylation of carbon-hydrogen bonds (PubMed:11555828, PubMed:12865317).  Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2 (PubMed:11555828, PubMed:12865317).  Metabolizes cholesterol toward 25-hydroxycholesterol, a physiological regulator of cellular cholesterol homeostasis (PubMed:21576599).  May act as a major enzyme for all-trans retinoic acid biosynthesis in the liver.  Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid (PubMed:10681376).  Primarily catalyzes stereoselective epoxidation of the last double bond of polyunsaturated fatty acids (PUFA), displaying a strong preference for the (R,S) stereoisomer (PubMed:19965576).  Catalyzes bisallylic hydroxylation and omega-1 hydroxylation of PUFA (PubMed:9435160).  May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent) (PubMed:21068195).  Plays a role in the oxidative metabolism of xenobiotics.  Catalyzes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin (PubMed:14725854).  Metabolizes caffeine via N3-demethylation (Probable).
What are the official names of this protein?
Cytochrome P450 1A2, CYPIA2, Cholesterol 25-hydroxylase, Cytochrome P(3)450, Cytochrome P450 4, Cytochrome P450-P3, Hydroperoxy icosatetraenoate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: TRPD_AERS4
Sequence: MHHHLNTLYQGQSLSRESTRDAFGQVVRGEVDPIVLASLLTALKIKGETPEEIAGAAEALLAEARDFPRPDYEFCDIVGTGGDGLNTINVSTTSALVAAACGLKVAKHGNRSVSSKSGSSDLLDKMGIKLDMSPAQARHCLDKLGICFLFAPQYHAGVRHAMPVRQALKTRTLFNVLGPLINPARPTYQLMGVYAPELVRPIAETLLALGLKTGMVVHGAGLDEIAIHGPTQVAQIRDGEIREFMITPADFGLETYPVSAIQGGEPEENRAITAAILAGQGTPAHNAAIAANVAPLLLMAGKAADLKSAAAEVLAVLASGKAAELAARLATLSHQEA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: HEMY_ECOLI
Sequence: MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGLAIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQVEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRVRLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTGAWSSLLDIIPSMAKAHVGDEEHRAMLEQQAWIGLMDQARADNGSEGLRNWWKNQSRKTRHQVALQVAMAEHLIECDDHDTAQQIIIDGLKRQYDDRLLLPIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTLGQSLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTLQNNPPQ
What is the function of this protein?
Involved in a late step of protoheme IX synthesis.
What are the official names of this protein?
Protein HemY.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURE_RICTY
Sequence: MKYNLNQLFKNYKINGLSTNSQTVKENEVFFALKGQNVDGNDFINDALNNGAVLVITENKKNTVIDKVIYVEDVYEALYEAIEIFYPKKPKNLISVTGTNGKSSVVSYIAQTYFLLRKKAAFIGTIGLEIFGCNNIINDVPSLTTLDYLNFRKIAHNLAEDSIEYLAFEASSHGLEQGRLGKTKVNIVSFTSFSQDHLDYHHTKENYLLAKLKLFTDHLLPSGIAILNSDIEEIEFVKDYLRNNNVKFITVGKKGDVQITKITCSLTGQNIDFIFNNIIYNLHTLIIGSFQASNLLIAALTLYYTGFKFDEIIEALSKVKPVKGRMERIDGTNIFVDYSHTPDALEKALIELQNIKPHGGKLSVIFGCGGDRDKTKRGLMGKIAAKFADNVIITDDNPRFEDPKLIRTEIIRGIGTATYTEIESREEAIKYGINNLKQDDILLIAGKGHENYQIVGDKKLPFDDSEVVRKYLFSMSCTRNQQKHLVSSRTVV
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KT3K_MOUSE
Sequence: METLLKRELGCSSVKATGHSGGGCISQGQSYDTDKGRVFVKVNSKAEARRMFEGEMASLTAILKTGTVKVPKPIKVVDAPGGGSMLVMEHLDMRYLSSHATKLGTQLADLHLENKRLGERLLKEAGTVGKGGEQAERQYVDQFGFDVVTCCGYLPQVNDWQKNWVEFYARQRIQPQMDMVEKKSGDREALELWSALQLKIPDLFRDLEIVPALLHGDLWGGNVAEDSSGPIIFDPASFYGHSEYELAIAGMFGGFSSSFYSAYHSKIPKTPGFEKRLQLYQLFHYLNHWNHFGSGYRGSSLNIMRNLSK
What is the function of this protein?
Ketosamine-3-kinase involved in protein deglycation by mediating phosphorylation of ribuloselysine and psicoselysine on glycated proteins, to generate ribuloselysine-3 phosphate and psicoselysine-3 phosphate, respectively (PubMed:14633848).  Ribuloselysine-3 phosphate and psicoselysine-3 phosphate adducts are unstable and decompose under physiological conditions (PubMed:14633848).  Not able to phosphorylate fructoselysine (PubMed:14633848).
What are the official names of this protein?
Ketosamine-3-kinase, Fructosamine-3-kinase-related protein, FN3K-RP, FN3K-related protein, Protein-psicosamine 3-kinase FN3KRP.
What is the protein family that this protein belongs to?
Belongs to the fructosamine kinase family.
Protein: HIS6_ACIAC
Sequence: MLAKRIIPCLDVTGGRVVKGVNFLELRDAGDPVEIAARYNGQGADELTFLDITATSDGRDLILPIIEAVASQVFIPLTVGGGVRTVEDVRRLLNAGADKTSFNSAAIANPEVIDAASAKYGAQCIVVAIDAKRRTPEEAARPGPDGAPRGEGWDVYSHGGRKNTGLDAVQWAAEMARRGAGEILLTSMDRDGTKSGFDLALTRAVSDAVSVPVIASGGVGGLDDLADGVQQGGADAVLAASIFHYGEYTVAQAKERMAARGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_BURO0
Sequence: MNDSVKTSLKRTLVGRVVSNKMDKTVTVLIEHRVKHPIYGKYVVRSKKYHAHDEANTYNEGDLVEIQETRPVSKTKAWTVSRLVEAARVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: COAX_ANADF
Sequence: MLLAIDVGNTNTVLGAYEGPSLRQHWRIETSHTRTYDEYGILVRQLFQVAGLDPAAVTAVAVSSVVPPLAFTLEQMSLRYFKVKPLFVGPGVKTGMSILYENPREVGADRVVNAVAAFERWRCGLIVVDFGTATTFDAVSPKGEYLGGAICPGIAISMDALFRHASKLPRVEFQRPPHVIGKNTVASIQSGLVYGYVGLVDGICARMADELGFAPKVVATGGLAALIAGVSKTVSEVDEHLTLDGLRLLHERNR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU3C_DIOEL
Sequence: MFLLHEYDIFWAFLIISSIIPILAFLISGVLTPIREGSEKLSSYESGIEPMGNAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGISVFIEAFIFVLIPIVGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AL3B2_HUMAN
Sequence: MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGHIINQKQFQRLRALLGCSRVAIGGQSNESDRYIAPTVLVDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIHYPPYTDWNQQLLRWGMGSQSCTLL
What is the function of this protein?
Oxidizes medium and long chain aldehydes into non-toxic fatty acids.
What are the official names of this protein?
Aldehyde dehydrogenase family 3 member B2, Aldehyde dehydrogenase 8.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Lipid droplet.
Protein: Y2983_BREBN
Sequence: MLKRLFVSGYKAHELGIFNEKNPGLAIIKKALKRELVRFLEEELEWVIISGQLGVEMWAAETVLELKKEYPHLKLAVITPFLNQEEKWKEETQDYYRNIVTQADYINSVYQTPYQGAWQLGEKDKFLLSNSDGILLVYDEENEGSPKFLSKLAAKKADNSDYQLFRINAYDLQAIAEEQQQELYNDSF
What are the official names of this protein?
UPF0398 protein BBR47_29830.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: RHEB_HUMAN
Sequence: MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSSCSVM
What is the function of this protein?
Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis.  Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling.  Has low intrinsic GTPase activity.
What are the official names of this protein?
GTP-binding protein Rheb, Ras homolog enriched in brain.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rheb family.
What are the subcellular locations of this protein?
Endomembrane system; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side.
Protein: XYLA_ECO5E
Sequence: MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAACMIEDGELDKRIAQRYSGWNSELGQQILKGQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRPA_PECAS
Sequence: MALGLSQVASQAASQTLDTAMAGSLTRAAGAQAQKIALDTENSILDGQMDSASKSLNSGQKAAKAIQF
What is the function of this protein?
Major structure protein of the hrp pilus, which is a component of the type III secretion system (TTSS, Hrp secretion system) required for effector protein delivery, parasitism, and pathogenicity.  The hrp pilus functions as a conduit for protein delivery into the host cell (By similarity).
What are the official names of this protein?
Hrp pili protein HrpA, TTSS pilin HrpA.
What is the protein family that this protein belongs to?
Belongs to the HrpA type 2 family.
What are the subcellular locations of this protein?
Secreted. Fimbrium. Note=Extracellular and secreted via type III secretion system.
Protein: FTSB_BORBR
Sequence: MRLLFLVLLVLLGLIQYPLWLGKGGWFKVWDLQRQVAEQRETNDGLRARNTALEAEVRDLATGVGAVEERARSELGMMREGEVFVHILPPGTPLPSDNSTPQASALSKPRPPATPPRR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: IRAK2_BOVIN
Sequence: MSCYIYQLPSWVLDDLCRNMDTLSEWDWMQFASYVITDLTQLRKIKSMERAQGVSITRELLWWWGMRQATVQQLLDLLCHLELYRAAQIILNWKPVLEVKSSIPDFSDTVKPGKPLAASVRNTEDKQETGQPVRPPTFPGSGPAAVRVNLPAPPEDASSSLKTNQTASADSKDFSASIPKQETLSSLAGDDLFWSEVDVIQATDNFNPSHKISEGTFADVYRGHKRGTPFIFKKLREMACSGPGSVEKFFQAEVQICRRCCHPNVLPLLGCCTGEQFYSLIYPYMANGSLQDRLQGQGGSDPLPWPQRISICSGLLHAVEHLHSLEIIHGNVKSSNVLLDQNFTPKLAHSMAHPCPVNRTSKYTMMKTHLFQASTAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGIPAMDNNRNPVYLKDLLLHEIPSSTISLCSRKMGVEKEMAKEICQKYLEKRAGRLPEAHAEALVMAACLCLRRRNASLAEVCSSVAAVEEQLRGQETSLPCSGLSEGTGSSFNTPEETDDVDNSSFDGSYSMRAAPWAGATSSPPLTADEEGMLLAGGAVEADSSAEACAPPEPPQDATETSWKIEINEAKRKLMENILLYKEEKLDSIELFGP
What is the function of this protein?
Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
What are the official names of this protein?
Interleukin-1 receptor-associated kinase-like 2, IRAK-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
Protein: CK054_XENTR
Sequence: MENCSFHVPSLEEICSVLKSGLLKNFADVSVIVTECPDLSKEPFEFPVKGLCGKSRIADVGGVPYLVPKPRLDKVYNVNAVAKKIGLPGAYILGAGATSHKSLGMNAELIFSVQAENESIQAVNKSYVASVNPGDGSCLLEKYRDRNNDNDFGLLSNLYACEGKPGKVIEVSVKRRIGQDNFVSCMRKSLKTHYGEKAVGLGGTFLLKEGKAKLHVMPREYSACPLNTDEDVNGWLKFYEMKAPLICQSVFVSHDPGYDLRLEHTHCFSHHGEGGHYHYDTTPDTVEYLGYFHPAELLYRIDKPSATHMVGRD
What is the function of this protein?
Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
What are the official names of this protein?
Ester hydrolase C11orf54 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: MRG1_ARATH
Sequence: MGSSSKEETASDGDTASGGASPSNDGRLFSEGERVLAYHGPRVYGAKVQKVELRKKEWKYFVHYLGWNKNWDEWVSADRLLKHTEENLVKQKALDKKQGVEKGTKSGRSAQTKTRSSADTKADKDDTKTNAAKGKKRKHESGNEKDNVTAEKLMKIQIPASLKKQLTDDWEYIAQKDKVVKLPRSPNVDEILSKYLEFKTKKDGMVTDSVAEILKGIRSYFDKALPVMLLYKKERRQYQESIVDDTSPSTVYGAEHLLRLFVKLPDLFSYVNMEEETWSRMQQTLSDFLKFIQKNQSTFLLPSAYDSDKVSDGKGKGKDD
What is the function of this protein?
Chromatin remodeling factor.  Acts as a 'reader' protein by binding to H3K36me3 and H3K36me3 to control histone H4 acetylation.  Increases the transcriptional levels of the flowering time genes FLC and FT (PubMed:25183522, PubMed:25211338).  Binds the chromatin at the FT promoter upon interaction with CO (Probable).
What are the official names of this protein?
Protein MRG1, MRG family protein 1, Morf Related Gene 1.
What are the subcellular locations of this protein?
Nucleus. Note=Localized only in the euchromatic regions.
Protein: Z_LATVB
Sequence: MGSKQSAPPKPLQLPQPRVSLLREAKPSLYGRYNCKCCWFQDKNLVECSDHYLCLKCISSMLKRGKNCEICGKAIPTYIEVGITPTAPQLN
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L.  Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z.  Also selectively represses protein production by associating with host eIF4E.
What are the official names of this protein?
RING finger protein Z, Protein Z, Zinc-binding protein.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae Z protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Mainly perinuclear. During budding, associates at the inner side of the plasma membrane of infected cells.
Protein: NORG_STAAB
Sequence: MKIPSQRQLAIQYNVNRVTIIKSIELLEAEGFIYTKVGSGTYVNDYLNEAHITNKWSEMMLWSSRQRSQYTVQLINKIETDASYIHISKGELGQPLMPHIQLKKAMSNTASHIEDLSFGYNNGYGYIKLRDIIVERMSKQGINVGRENVMITSGALHAIQLLSIGFLGQDAIIISNTPSYIHSTNVFEQLNFRHIDAPYNQINEINTIIDRFINFKNKALYIEPRFNNPTGCSLTNEQKQNIITYSERHNIPIIEDDIFRDIFFSDPTPAIKTFDKLGKVIHISSFSKTIAPAIRIGWIVASEKIIEQLADVRMQIDYGSSILSQMVVYEMLKNKSYDKHLVKLRYVLKDKRDFMLNILNNLFKDIAHWEVSSGGYFVWLVFKIDIDIKYLFYELLSKEKILINPGYIYGSKEKSIRLSFAFESNENIKHALYKIYTYVKKV
What is the function of this protein?
Positively regulates the expression of the NorB efflux pump and negatively regulates the expression of the AbcA efflux pump.  Binds specifically to the promoters of norA, norB and norC and abcA genes.  Could also have an aminotransferase activity (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator NorG.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: FOLD_SALAR
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARVAAGLRAPGLAVVLVGSNPASQIYVASKRKACDEVGFVSRSYDLPETTSEAELLELIDTLNADSTIDGILVQLPLPAGIDNVKVLERIAPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTYGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKDLRHHVEHADLLIVAVGKPGFIPGEWIKEGAIVIDVGINRLENGKVVGDVVFEEAAARASYITPVPGGVGPMTVATLIENTLQACTEYHDPQGK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: TRI44_RAT
Sequence: MASGVGAACEELPPDGTCDECEPDEAPGAEEVCRDCGFCYCRRHADAHRQKFLSHRLAAYVHGAQAWTPPASGDDALPEDVEAKGEAEGEVESEVGEEESESEVDSESEEESETEEDSEDESDEESEEDSEEEMEDEQESEAEEDNQEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGAHRGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKVFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPSGASEEEDT
What is the function of this protein?
May play a role in the process of differentiation and maturation of neuronal cells (By similarity).  May regulate the activity of TRIM17 (By similarity).  Is a negative regulator of PAX6 expression (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 44, Protein DIPB.