PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_GEOSL
Sequence: MAADKRDYYEVLGVHKNASDTEIKKAFRKLAIQYHPDKNPDDKEAEEKFKEITEAYEVLSDPQKRAQYDQFGHAGVGAGGFSGGGFGGFGAGTPFGDIFGDIFGDIFGGRPRGSRGRRGDDLQYNMELSFEEAAFGAEKEIQVPYGKRCGDCGGSGAKPGTEPKVCPTCRGAGQVRFQQGFFSVSKTCNHCNGEGRVVENPCTSCRGSGMIRDTKTLSVKVPAGVETGTRLKLSGEGGQGIKGGGNGDLYVAIAVREHPIFTREDNDVLCEIPVSFVQAALGCEIEVPTLDGKVSMKIPEGTQSGRIFRLRGKGVPQLQGYGRGDQLVIIKVETPSNLNKRQRELLEEFARISGEDVHPMKKSFFDKVMDFIS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUS_SV41
Sequence: MRLTPYPIALTTLMIALTTLPETGLGIARDALSQVGVIQSKARSLMYYSDGSSSFIVVKLLPTLPTPSGNCNLTSITAYNTTLFKLLTPLMENLDTIVSANQAGSRRKRFAGVVVGLAALGVATAAQVTAAVAVVKANANAAAINKLAASIQSTNAAISDVISSTRTLATAIQAVQDHVNGVLASGLTEANCRSQDALIGSILNLYLTELTTIFHNQIVNPALTPLSIQALRIILGSTLPLIVESRWNTNLNTAELLSSGLLTGQIISISPSYMQMVIQITVPTFVMQPGAKIIDLVTITANRMEEEVLIQVPPRILEYANEIQAYTADDCVVTPHAVFCKYNDGSPISDSLYQCLKGNLTSCVFTPVVGNYLKRFAFANGVMYVNCKALLCRCADPPMVITQDDLAGITVIDITVCREVMLDTLAFKITSLNNVTYGANFSMLAAAIKDLSPLDLSAQLAQVNKSLASAEEKIAQSSSLAAQAVSQEATITVGSVAMLIAVLALIAGCTGIMIAVQMSRRLEVLRHLTDQSIISNHHYAELNPPPYNHSYESLHPIPQSH
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with HN at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: RNH_SHEB9
Sequence: MTELKLIHIFTDGSCLGNPGPGGYGIVMNYKGHTKEMSDGFALTTNNRMELLAPIIALESLKEPCQVVLTSDSQYMRQGIMTWIHGWKKKGWMTSNRTPVKNVDLWKRLDKASQMHTIDWQWVKGHAGHAENERCDVLARTAAESKPTQPDLGYQP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_STRSY
Sequence: MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMEDDVVNEFAKNLLAAKRDLSYCSICGNLTDQDPCAICQDSTRDQSTILIVEDSRDVTALENIQEYHGLYHVLHGLISPMNGIGPDDINLKTLLTRLMENEVTEVIVATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RL23_ACIAD
Sequence: MNNERIYQVLKGPVFSEKAQVLGETAGVQVFKVDINATKLEIKKAVEKLFGVDVLKVNTTITKGKSKRFGKTLGRRSDVKKAYVTLKAGQDVEMADLGDTAESAAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: B1S2_LOXSN
Sequence: FALAHMVNDFDIMKSYLDEGANGIETDITFSPEGEPESAFHGVPCDCKRWCDRTVSFDSYLQKTSDLSTPGHPDYRENLLIIILDLKLNGLSQDALANGGRRLADKLAAHFWTGGRRDQRATFVVSVPQTSQKVFMKTFREEMEAIGMGDMNAKVGFDFTDNGDVSVTKAVYDELGITEHIWASDGITNCVALLFRGTSRLEELIQKRDEGESTYISKVYAWTYDKETSVVLALELGVDGVMTNYADFVISILNKPEHSSKYRLATYEDDPFERFKAV
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LspiSicTox-betaIE2ii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMP_ECOLI
Sequence: MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits, probably at a late stage of ribosomal protein binding, while Era is associated and after RimM (PubMed:20188109).
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_BACC0
Sequence: MRKPIIAGNWKMNKTLSEAVSFVEEVKGQIPAASAVDAVVCSPALFLERLVAATEGTDLQVGAQNMHFEKNGAFTGEISPVALSDLKVGYVVLGHSERREMFAETDESVNKKTIAAFEHGLTPIVCCGETLEERESGKTFDLVAGQVTKALAGLTEEQVKATVIAYEPIWAIGTGKSSSSADANEVCAHIRKVVAEAVSPAAAEAVRIQYGGSVKPENIKEYMAQSDIDGALVGGASLEPASFLGLLGAVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_VIBCM
Sequence: MKPAKQTTASLAFLAMGIVYGDIGTSPLYAFKEVFFSHHPLAINPDNVLGILSLVFWAFVLIVSIKYLLLVTRADQNGEGGILTLSAIAQQSAPKPWQRIAMLLGILATGFFFGEAVITPAMSVLSAVEGIAVAQPDLAPYVLPIAMMIIVALFAVQAMGTERIGRFFAPVMLLWFLVLALLGAHAIWHAPQVLRALNPAYAVHFVLLYGQHTLFILGLVVLSVTGVEALYADMGHFGIKPIRIAWFALVMPSLLLNYFGQGAYLLTLSAPTGSTFFSLAPKAWLWPLILLATFATVIASQAVISGIFSLARQAINYGYLPPMKIAHTSEHSQGQIYVPAANMLLFVAVIFVMLRFRSSANLAAAYGIAVTAIMMISSLLLVLVARYQWQWRWPRVVTIGIVFIGMDSLLLASTSTKLMEGGWLPLLLGCVVFIVMYIWQQQRQRLLEIAGNELSVSAMIQSLEEESFQRAAGTAVYLSRSLNHVPRSLLHNIKYNKTLHERNVLMTFQYEAVPRVHPCRRAEIEQVSASFWQVVIHIGYQEEPDMAQVMHCCGLKGLYLHPNETLFLLSSERLKVQKLGMWHDLKVWFFIQMSKHALRTSERLNIPPDRLIEMGVYREM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURT_THIDA
Sequence: MRLGTPLSPSATRVMLLGAGELGKEVIIALQRLGVEVVAVDRYEHAPGHQVAHRAHVIDMTDGAALRALIEAEKPLLVVPEIEAIATEALLEIERAGLAEVIPTARAVNLTMNREGIRRLAAETLGLPTSPYAFVDSYAEMCAAAERLGYPVIVKPVMSSSGKGQSRVDDAGEMRAAWDYAVRGGRVDKGRFIVEGVIDFDYEITLLTVRARAASGAIETRFCAPIGHLQVKGDYVESWQPQAMSPTALERAREIAAAVTGELGGRGLFGVELFVKGDTVWFSEVSPRPHDTGMVTLATQRQNEFELHARAILGLPVDTGLREPGASAVIYGAVDARGIAFDGVDDALAAPGVDLRLFGKPEAFARRRMGVALATADSPDAARLLAKAAAAKVKPVPV
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: DNLJ_NAUPA
Sequence: MIKDYNDYKKAVDTLKKWAYYYYVLDNPLVTDEEYDKLYHEVEEYEKKHPDKIDPTSPTQRVGDVVLEGFEKAKHLSRMWSMEDVFNEKDFLDWVGRVKRILGHENFSFYIEPKFDGASLNLIYENGKLIRAETRGDGEIGEDVTLNAKTINSIPLEIKEKSLIEIRGEVVIKKDDFDKLNEERLKNGEPTFANPRNAAAGSLRQLDPKITAKRPLIFYPWGVGVNSLNYERYSELMDYIYSLGFKEPPKRGVCKDIPCVEKKYDEFVKLRDSFEVMLDGMVVKIDEIKYHDILGYTQKYPRWMVAYKFPAIEKETIIEDVIVQVGRTGVLTPVAVLKPVEIGGVIVERATLHNFDEIERMDIRIGDHVIVIRSGDVIPKITKVLTWKRKGDEKPIPRPTHCPVCGAEVLDEGALIKCQNLSCPARVVNTIIYFASKNCLDIEGLGESVAKLLYEHGLVKDVTDLFELKVEDLEKLPLFARKKAENLVNAIKSKVGVECWRFVNALGIEHIGEVASKKICEKFGVEFYKHAPEEFEEIEGFGPEMVKSIAEYIRVNKEKIEKLIEILKPKNPEKKEVQKTPFTGKTVVLTGTMSKPRSEIKKMLEDMGAKVSSSVSKKTDFVIYGEDAGSKYDKAKKLGVNLLSEDDMWKMLKEGK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ALLSC_CAMFO
Sequence: MSSVRNIAALALVLLVLAEWSAAMPTTDKDKERLLNTVDLIDDDGSIETALINYLFTKQIVKRLRSQLDIGDLQRKRSYWKQCAFNAVSCFGK
What is the function of this protein?
Inhibits juvenile hormone biosynthesis.
What are the official names of this protein?
Allatostatin C.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOA_LACGA
Sequence: MIEFEKPNITVVDQEEAYGKFVVEPLERGFGTTLGNSLRRVLLTSIPGTALSYIQIDGVLHEFSTVPGVREDVTKIILNLKKLELKSLSDEEKIAEIDVTGPAIVTAADLKVDSDIEVLNPDQYICSIADGGHLHMNVAIKNGRGYVPASENKTDDMPIGVIPVDSLFSPIKKVNYQVESARVGKRDDYDKLTLEIWTDGSITPNDALSFAAKILVEHFKVFMSTDMDAQFDDVMVEKEDDKNEKKLEMTIEELDLSVRSYNCLKRAGINTVQELTDKSEADMMRVRNLGRKSLEEVKNKLAELGLSLRQDD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: NFI_TRIV2
Sequence: MQIYQPHPWPLTVEEAITIQEELRHQVITQDQFTQPVQYVAGVDMGFEADGTISRAAVAVLSFPDLQVVETSLAYRPTSFPYIPGFLSFREIPAVLDALEKIQTKPDIILCDGQGIAHPRRLGIASHLGVLLNIPTIGVAKSLLIGRHEELADTKGSWQPLIHRGEIIGAVLRTRVGVKPVYVSSGHKISLPTAIDYVLRCTPKYRLPETTRVADKLASNR
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_AERHH
Sequence: MSIILGIDPGSRITGYGVIRIVAGKAEYLGSGCIRTDLGELPSRLKQVYDGVSEIITQFKPDEFAIERVFMARNADSALKLGQARGSAIVAAVNALLPVSEYSATQIKQAVVGTGGAAKEQVQHMVTHLLKLSATPQADAADALGVALCHFHTRQILIKMAGRSTGSVRGRYR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CYSD_ECO24
Sequence: MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: AFF2_HUMAN
Sequence: MDLFDFFRDWDLEQQCHYEQDRSALKKREWERRNQEVQQEDDLFSSGFDLFGEPYKVAEYTNKGDALANRVQNTLGNYDEMKNLLTNHSNQNHLVGIPKNSVPQNPNNKNEPSFFPEQKNRIIPPHQDNTHPSAPMPPPSVVILNSTLIHSNRKSKPEWSRDSHNPSTVLASQASGQPNKMQTLTQDQSQAKLEDFFVYPAEQPQIGEVEESNPSAKEDSNPNSSGEDAFKEIFQSNSPEESEFAVQAPGSPLVASSLLAPSSGLSVQNFPPGLYCKTSMGQQKPTAYVRPMDGQDQAPDISPTLKPSIEFENSFGNLSFGTLLDGKPSAASSKTKLPKFTILQTSEVSLPSDPSCVEEILREMTHSWPTPLTSMHTAGHSEQSTFSIPGQESQHLTPGFTLQKWNDPTTRASTKSVSFKSMLEDDLKLSSDEDDLEPVKTLTTQCTATELYQAVEKAKPRNNPVNPPLATPQPPPAVQASGGSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNKWQLDKWLNKVTSQNKSFICGQNETPMETISLPPPIIQPMEVQMKVKTNASQVPAEPKERPLLSLIREKARPRPTQKIPETKALKHKLSTTSETVSQRTIGKKQPKKVEKNTSTDEFTWPKPNITSSTPKEKESVELHDPPRGRNKATAHKPAPRKEPRPNIPLAPEKKKYRGPGKIVPKSREFIETDSSTSDSNTDQEETLQIKVLPPCIISGGNTAKSKEICGASLTLSTLMSSSGSNNNLSISNEEPTFSPIPVMQTEILSPLRDHENLKNLWVKIDLDLLSRVPGHSSLHAAPAKPDHKETATKPKRQTAVTAVEKPAPKGKRKHKPIEVAEKIPEKKQRLEEATTICLLPPCISPAPPHKPPNTRENNSSRRANRRKEEKLFPPPLSPLPEDPPRRRNVSGNNGPFGQDKNIAMTGQITSTKPKRTEGKFCATFKGISVNEGDTPKKASSATITVTNTAIATATVTATAIVTTTVTATATATATTTTTTTTISTITSTITTGLMDSSHLEMTSWAALPLLSSSSTNVRRPKLTFDDSVHNADYYMQEAKKLKHKADALFEKFGKAVNYADAALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMRLKNFASPLASDGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVAQIPSPWVSNGKNTPSPVSLNNVSPINAMGNCNNGPVTIPQRIHHMAASHVNITSNVLRGYEHWDMADKLTRENKEFFGDLDTLMGPLTQHSSMTNLVRYVRQGLCWLRIDAHLL
What is the function of this protein?
RNA-binding protein.  Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure.
What are the official names of this protein?
AF4/FMR2 family member 2, Protein FMR-2, FMR2P, Protein Ox19.
What is the protein family that this protein belongs to?
Belongs to the AF4 family.
What are the subcellular locations of this protein?
Nucleus speckle. Note=When splicing is inhibited, accumulates in enlarged speckles.
Protein: IHFA_ECOL6
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: CP4B1_RAT
Sequence: MVLNFLSPSLSRLGLWASVVILMVIVLKLFSLLLRRQKLARAMDSFPGPPTHWLFGHALEIQKLGSLDKVVSWAQQFPHAHPLWFGQFVGFLNIYEPDYAKAVYSRGDPKAADVYDFFLQWIGKGLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRMMLDKWEKKASENKSFDIFCDVGHMALDTLMKCTFGKGDSGLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLTPHGRRFLRACKIAHDHTDEVIRQRKAALQDEKERKKIQQRRHLDFLDILLGVRDESGIKLSDAELRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQDSFQWDDLAKMTYLTMCMKECFRLYPPVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVWPDPEVFDPLRFSPENAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPIKVPQLILRSKNGIHLYLKPLASRSGK
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 4B1, CYPIVB1, Cytochrome P450 L-2, Cytochrome P450 isozyme 5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: PEN3K_PENST
Sequence: MRLVVCLVFLASFALVCQGQGYKGPYTRPILRPYVRPVVSYNACTLSCRGITTTQARSCCTRLGRCCHVAKGYSG
What is the function of this protein?
Antibacterial and antifungal activity.  Presents chitin-binding activity (By similarity).
What are the official names of this protein?
Penaeidin-3k, Pen-3k.
What is the protein family that this protein belongs to?
Belongs to the penaeidin family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Protein: HSLO_CLOBB
Sequence: MKDKIIRATAKNGMVRIIGGITTNLVNEGSKIHQCTPVAAAALGRMLTAGTLMGTTLKGEKEALTLKINGGGEAKGITVTAHNDASVKGFIGNPYVTRELNDKGKLDVGGAIGKDGLLYVIKDLGLKEPYVGQVPIYSGEIAEDFAYYFTVSEQTPSAVSLGVLVDKNLSIKAAGGFIVQMMPDADELLADLVTYRLEEIPPITTLISEGKSIEEILEFIFEGMDLNILDSIEPKYKCDCSREKVEKALASIGKNELQEIYDDGKNEEIVCNFCNTKYTFTTNDIDKLLKNSIKK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1A_BOMMO
Sequence: MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSTEPPYSEPRFEEIKKEVSSYIKKIGYNPAAVAFVPISGWHGDNMLEPSTKMPWFKGWQVERKEGKADGKSLIEALDAILPPARPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGTIVVFAPANITTEVKSVEMHHEALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKNNPPKGAADFTAQVIVLNHPGQISNGYTPVLDCHTAHIACKFAEIKEKVDRRTGKSTEVNPKSIKSGDAAIVNLVPSKPLCVESFQEFPPLGRFAVRDMRQTVAVGVIKAVNFKEAGGGKVTKAAEKATKGKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEZ_SHISS
Sequence: MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEAAEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPIDLADARELVTDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGLVIKRMMDVIQEIERQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKVGVVASQDQVDDLLDSLGF
What is the function of this protein?
Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
What are the official names of this protein?
Protein phosphatase CheZ, Chemotaxis protein CheZ.
What is the protein family that this protein belongs to?
Belongs to the CheZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y997_STAA3
Sequence: MEYEYPIDLDWSNEEMISVINFFNHVEKYYESGVTAGDFMGAYKRFKEIVPAKAEEKQIFNTFEKSSGYNSYKAVQDVKTHSEEQRVTAKK
What are the official names of this protein?
UPF0223 protein SAUSA300_0997.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: Y767_MYCTO
Sequence: MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYADLTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPCVTDVNVPMPIRVTSSLRHLALVVADEPEIGAACTAALLDGGADPAVRAVRDRIGAEIHRRITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTYHEIADRLGYVVGLILAGANEPSTGGSE
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MT0791.
Protein: MAL2_PONAB
Sequence: MSAGGASVPPPPNPAVSFPVPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVPLPLLQGWVMFVSVTAFFFSLLFLGLFLSGMVTQIDANWNFLDFAYHFTVFVFYFGAFLLEAAATSLHDLHYNITMTGQPLLNDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
What is the function of this protein?
Member of the machinery of polarized transport.  Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway (By similarity).
What are the official names of this protein?
Protein MAL2.
What is the protein family that this protein belongs to?
Belongs to the MAL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Note=Associated with lipid rafts. In polarized epithelial cells, restricted to the apical surface (By similarity).
Protein: LBH_HUMAN
Sequence: MSIYFPIHCPDYLRSAKMTEVMMNTQPMEEIGLSPRKDGLSYQIFPDPSDFDRCCKLKDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKEQ
What is the function of this protein?
Transcriptional activator which may act in mitogen-activated protein kinase signaling pathway.
What are the official names of this protein?
Protein LBH, hLBH, Limb bud and heart development protein homolog.
What is the protein family that this protein belongs to?
Belongs to the LBH family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.