PharMolix/UniProtQA huggingface dataset:
Protein: FEN_PYRAE
Sequence: MGVTELGKLIGKEVRREVKLESLSGKCIALDAYNALYQFLASIRQPDGTPLMDRAGRITSHLSGLFYRTINLLEAGIRPVYVFDGKPPEFKLAEIEERRKTREKAMEEVLRAIKEGRREDVAKYAKRAVFITSEMVDEAKRLLSYMGVPWVQAPSEGEAQAAYMARKGHCWAVGSQDYDSLLFGSPKLVRNLAVSPKRKIGEEVIELTPEIIELDAVLRALRLKNREQLIDLAILLGTDYNPDGVPGVGPQKALKLIWEFGSLEKLLETVLKGAYFPIDPLEIKKFFLNPPVTDQYATEVRDPDEAALKDFLIREHDFSEERVSKALERLRKARGKLKTSSLDSFF
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: ARF1_DICDI
Sequence: MGLAFGKLFSRFFGKKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEFKNINFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEACDELTKMLNEDELRDAVLLVFCNKQDLPNAMSVAEVTDKLNLHSLRSRKWYIQSTCATSGDGLYEGLDWLSNTLTSSSK
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: RPIA_ECOSE
Sequence: MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGVVTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIVK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SYE_PSYIN
Sequence: MKVKTRFAPSPTGFLHVGGARTALYSWLHAKSKGGEFVLRIEDTDIARSTQEAVDAILEGMTWMGLTWDEGPYYQTKRFDRYKEIIAKMLSDGTAYKCYCTKERVNELREAQEKAGESPRYDSKCRGLAPQNTDAPYVIRFKNPKEGSVKFDDHVRGPIEFSNTELDDLIIQRTDGTPTYNFCVVVDDWDMGITYVVRGEDHINNTPRQINILKALGAPLPEYAHVAMILGDDGAKLSKRHGAVSVMQFRDEGYLPEALKNYLVRLGWSHGDQEIFSEKEMIELFSLDAINKAPSAFNTEKLLWLNQHYIKSLDPAYIAQHLAWHMTNQKIDMTNGPALPEIVSALSERAKTLVELATTSRYFFEEYEDFDATAAKKHLRPVAEDALVLVKQKLQTSDDWTDPALHQIINDTANELGVGMGKVGMPLRVAITGGGQSPSLDVTLRLIGKERSIKRIDRALEFIAARVAAS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEIL3_MOUSE
Sequence: MVEGPGCTLNGEKIRARVLPGQAVTGVRGTALQSLLGPAMSPAASLADVATSAAPMNAKDSGWKLLRLFNGYVYSGVETLGKELFMYFGPRALRIHFGMKGSILINPREGENRAGASPALAVQLTRDLICFYDSSVELRNSVESQQRVRVMEELDICSPKFSFSRAESEVKKQGDRMLCDVLLDQRVLPGVGNIIKNEALFDSGLHPAVKVCQLSDKQACHLVKMTRDFSILFYRCCKAGSAISKHCKVYKRPNCDQCHSKITVCRFGENSRMTYFCPHCQKENPQCVQVCQLPTRNTEISWTPRGEDCFTDSVARKSEEQWSCVVCTLINRPSAKACDACLTTRPLDSVLKNRENSIAFNNLVKYPCNNFENTHTEVKINRKTAFGNTTLVLTDLSNKSSALARKKRANHTIDGESQMFLPTDIGFSDSQHPSKEGINYITQPSNKVNISPTVCAQSKLFSSAHKKFKPAHTSATELKSYNSGLSNSELQTNRTRGHHSKSDGSPLCKMHHRRCVLRVVRKDGENKGRQFYACSLPRGAQCGFFEWADLSFPFCRHGKRSIMKTVLKIGPNNGKNFFVCPLEKKKQCNFFQWAENGPGMEIVPGC
What is the function of this protein?
DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA) (PubMed:20185759, PubMed:22065741, PubMed:22569481, PubMed:22959434, PubMed:23305905, PubMed:23313161).  Mediates interstrand cross-link repair in response to replication stress: acts by mediating DNA glycosylase activity, cleaving one of the two N-glycosyl bonds comprising the interstrand cross-link, which avoids the formation of a double-strand break but generates an abasic site that is bypassed by translesion synthesis polymerases (By similarity).  In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA (PubMed:20185759, PubMed:22065741, PubMed:22569481, PubMed:22959434, PubMed:23305905, PubMed:23313161).  No activity on 8-oxoG detected (PubMed:20185759, PubMed:22065741, PubMed:22569481, PubMed:22959434, PubMed:23305905, PubMed:23313161).  Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity (PubMed:20185759, PubMed:22065741, PubMed:22569481, PubMed:22959434, PubMed:23305905, PubMed:23313161).  In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues (PubMed:20185759, PubMed:22065741, PubMed:22569481, PubMed:22959434, PubMed:23305905, PubMed:23313161).
What are the official names of this protein?
Endonuclease 8-like 3, DNA glycosylase FPG2, DNA glycosylase/AP lyase Neil3, Endonuclease VIII-like 3, Nei-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PDRP_CLOD6
Sequence: MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYMINKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKRTGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTPLSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGLSSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYKEIEI
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: METXS_BORPA
Sequence: MTSPVLNPALPATAAAPVAATPSAVGSAGIVAPVFLRFDEPLPLASGQTLNGYELAIETYGTLNAQRTNAVLVCHALNASHHVAGVSADNPKDVGWWDNMVGPGKPVDTNRYFVIGVNNLGSCFGSTGPASINPATGRPWGAAFPVLTVEDWVRAQARVADHFGIERFAAVMGGSLGGMQALSWAITCPQRVANCVVVASTPRLSAQNIGFNEVARRAIITDPDFHGGDYYAHGTVPGRGLSVARMIGHITYLSDDDMAEKFGRTRREPAADGAYRYGYDVEFEVESYLRYQGEKFSRYFDANTYLLITRALDYFDPARATGGDLARALAPATADFLLVSFSTDWRFPPERSREMVRALLKNGSPVTYAEIDAPHGHDAFLLDDARYHAVVRGYYERIARELGLNGAVAPEGNPA
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIK1_ARATH
Sequence: MEKATERQRILLRHLQPSSSSDASLSASACLSKDSAAYQYGDDVVIVAAQRTALCKAKRGSFKDTFPDELLASVLRALIEKTNVNPSEVGDIVVGTVLGPGSQRASECRMAAFYAGFPETVPIRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTTNPRGWKGSVNPNVKKFEQAHNCLLPMGITSENVAHRFNVSREEQDQAAVDSHRKAASATASGKFKDEITPVKTKIVDPKTGDEKPITVSVDDGIRPNTTLSGLAKLKPVFKEDGTTTAGNSSQLSDGAGAVLLMRRNVAMQKGLPILGVFRTFSAVGVDPAIMGVGPAVAIPAAVKAAGLELNDVDLFEINEAFASQFVYCRNKLGLDAEKINVNGGAIAIGHPLGATGARCVATLLHEMKRRGKDCRFGVVSMCIGSGMGAAAVFERGGGVDELCDVRKV
What is the function of this protein?
Involved in fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth.  Implicated in jasmonic acid (JA) biosynthesis (By similarity).
What are the official names of this protein?
3-ketoacyl-CoA thiolase 1, peroxisomal, Acetyl-CoA acyltransferase 1, Beta-ketothiolase 1, Peroxisomal 3-oxoacyl-CoA thiolase 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RGMG_CALS4
Sequence: MGEVLIRMENISKEFPGVKALKNVNFEIKKGEVHALVGENGAGKSTLIKILSGVYSKDSGKIYFDGREVEINSPKEAQQLGISVIHQELNLCLHLTVAQNIFLGREFVKNGVIDEKKQNEEAKKILEKLNVNIDPAEYVKNLSVSRQQMVEIAKAISMEAKVIIMDEPTSAISEKETEELFKVIGELKKQGKSIIYISHRLEELNRIVDRVTVLRDGEHIITANFRDLTIDDIIRYMVGRKLEEKYPRVYVNRGKKILEVHGLSQGTRLKDISFDLYEGEILGFAGLVGAGRTEVARAIFGADKFDKGEILINGKKVEINSPIDAIKNGLAYVPEDRKLTGLALNLSVLANITLATMDNVVNMLSVINSVKERKIGEKIIRDLKIKTPSLFQRVQNLSGGNQQKVIVGRWLLREPQIYIFDEPTRGIDVGAKIEIYNILNNLKQEGKGIIVISSELPEIMGITDRVVVMCEGRITAILETSKTTQEEIMYYATLYKKERSN
What is the function of this protein?
Part of an ABC transporter complex involved in carbohydrate import.  Could be involved in ribose, galactose and/or methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Putative ribose/galactose/methyl galactoside import ATP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYDND_ACIBC
Sequence: MMRTHYCGSLTEAQIDQTVTLCGWVHRRRDHGGVIFLDMRDRDGLVQVVIDPDTPEAFATADKARSEYVLKITGRVRRRYEGTENPNMVSGQIEVLGKEIEVLAASETPPFPLNDDTINVSEEHRLKYRFLDIRRPEMLERLRFRSKVTNLIRNYLDDHGFLDVETPILTRATPEGARDYLVPSRVQNGSFYALPQSPQLFKQLLMVGGIDRYYQIAKCFRDEDLRADRQPEFTQIDIETSFLNDDDIMDLMEGMTVKLFNDLLGVKFEKFRRMPYSEAMRDYASDKPDLRIPLKLVDVADLMQEVEFKVFAGPAKDPKGRIAALRVPGAGSLTRSQIDEYTKFVGIYGAKGLAYIKVNEIEKGIEGLQSPIVKFIEPIVMQLLERVGAENGDIVFFGADKAKIVNDAMGALRVKIGHDLNLATCEWAPLWVVDFPMFEETDDGKWTSVHHPFTLPKSSVEDVKSNPGEALSVAYDMVLNGTEVGGGSLRIYTLEMQKAIFEALGISDEEAEEKFSFLLNALRYGAPPHGGLAFGLDRLVMLMTGATSIRDVIAFPKTKTAECPLTQAPAPVEANQLRDLGIRLREQQKKEA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBHA_ASPNG
Sequence: MHQRALLFSALLTAVRAQQAGTLTEEVHPSLTWQKCTSEGSCTEQSGSVVIDSNWRWTHSVNDSTNCYTGNTWDATLCPDDETCAANCALDGADYESTYGVTTDGDSLTLKFVTGSNVGSRLYLMDTSDEGYQTFNLLDAEFTFDVDVSNLPCGLNGALYFTAMDADGGVSKYPANKAGAKYGTGYCDSQCPRDLKFIDGQANVDGWEPSSNNDNTGIGNHGSCCPEMDIWEANKISTALTPHPCDSSEQTMCEGNDCGGTYSDDRYGGTCDPDGCDFNPYRMGNDSFYGPGKTIDTGSKMTVVTQFITDGSGSLSEIKRYYVQNGNVIANADSNISGVTGNSITTDFCTAQKKAFGDEDIFAEHNGLAGISDAMSSMVLILSLWDDYYASMEWLDSDYPENATATDPGVARGTCDSESGVPATVEGAHPDSSVTFSNIKFGPINSTFSASA
What is the function of this protein?
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
1,4-beta-D-glucan cellobiohydrolase A, Beta-glucancellobiohydrolase A, Cellobiohydrolase D, Exocellobiohydrolase A, Exoglucanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOH2_RHOPB
Sequence: MIGMALTAIISTMLIMVLLVVAGTFTWVERRVLGFVQERLGPNRVGPFGFLQWVADTVKILTKEDRPPPGADRVAYILAPMVAATPVLAGFGVVAFGDGLALANIDVGVMFLLGMMGLTVYGVVLGALASHSRFALMGGLRAAAQMLGYEAFLGLSLLGVVMIAGSLSLTEIVHAQRDVWFVLLQPFGAALFCIAGVAAAHRLPFDLPESENDLVAGYLTEYTGMSFGLFFLGEYLAVLLVASLAVTLFFGGWLGPVWLGPYLPGPIWFGLKVGVIALIFIWIRATLPRPRYDQLVRFAWKIALPLALANLLLTGLIVVARSAP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H 2, NADH dehydrogenase I subunit H 2, NDH-1 subunit H 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FEN11_ORYSI
Sequence: MGIKGLTKLLADNAPKAMKEQKFESYFGRRIAVDASMSIYQFLIVVGRTGMETLTNEAGEVTSHLQGMFNRTIRLLEAGIKPVYVFDGKPPDLKKQELAKRYSKREDATKELTEAVEEGDKDAIEKFSKRTVKVTKQHNEECKRLLRLMGVPVVEAPCEAEAECAALCINDMVYAVASEDMDSLTFGAPRFLRHLMDPSSKKIPVMEFEVAKVLEELELTMDQFIDLCILSGCDYCDSIKGIGGQTALKLIRQHGSIESILENINKDRYQIPEDWPYQEARRLFKEPNVTLDIPELKWNAPDEEGLVQFLVKENGFNQDRVTKAIEKIKFAKNKSSQGRLESFFKPVVSTSVPLKRKDTSEKPTKAVANKKTKGAGGKKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1-A, FEN-1-A, Flap structure-specific endonuclease 1-A.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: PPX_SALTI
Sequence: MPIYDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQRVHLADGLGADNKLSEEAMERGLSCLSLFAERLQGFSPSSVCIVGTHTLRQAQNAADFLKRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPRLVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQYRIQGWNVAMGASGTIKAAHEVLLALGEKDGFITPERLDKLKSEVLKHRSFNALSLPGLSEERKAVFVPGLAILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTAKSLANQYNIDREQARRVLETTMQMYEQWQAQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQHSDLPGFNQEQQMMMATLVRYHRKAIKLDDMPRFTLFKKKQYLPLIQLLRLGVLLNNQRQATTTPPTLRLTTDDSHWTLCFPHDWFSQNALVLLDLEKEQQYWEAVTGWRLNIEEESSPEIAA
What is the function of this protein?
Degradation of inorganic polyphosphates (polyP).  Releases orthophosphate processively from the ends of the polyP chain.
What are the official names of this protein?
Exopolyphosphatase, ExopolyPase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL16_ACIBT
Sequence: MLQPKRTKFRKVHKGRNTGLAHRGSTVSFGSIAIKATERGRMTARQIEAARRTISRRIKRGGKIFIRVFPDKPITEKPLEVRMGNGKGNVEYWVCEIKPGKILYEIEGVNEDLAREAFALAAAKLPFKTTIVTRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: FTSB_SHESW
Sequence: MKFFVIALIVLLGLLQYRLWSGSNSLPEYFVLQKHIAVQQEGNDKLNERNQVLKEEIIDLKSGTEAIEERARNELGMVKEGETFYRVVGGERSVSSPSQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: GPA5_DICDI
Sequence: MGCILTIEAKKSRDIDYQLRKEEGSKNETKLLLLGPGESGKSTIFKQMKIIQDDGGFSIDERLEYRYIIYGNCISQMKVLVTAAISQDLKPNNPDNETRFEKFSKISPGGNSWTLEIAEDIKQLWSDDSIQNIYRMKDKFYQLNDSAAYFFDNIGRFANENYVPTQDDVLRSRVRTTGIQEAHFKFINIEFRMLDVGGQRSERRKWIHCFDSVTAVIFCVALSEYDQTLREEESQNRMKESLMLFDEIVNSHWFRNTAFIIFFNKVDLFREKIAKIDLGDYFPAYTGGLSFDNSTQFIKKMFLDLSTGNQRIFAHFTCAIDTANIQFVFHAVRETLLKNIFNTIINY
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-5 subunit, G alpha-5.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
Protein: TRPB_METRJ
Sequence: MTIAPEPNSFRTGPDERGRFGIFGGRFVAETLMPLILELEAAYETAKKDPAFQAEMESYGTHYIGRPSPLYYAERLTEHLRAKAPAGQGAKVYFKREELNHTGSHKVNNVLGQILLARRMGKPRIIAETGAGQHGVATATLCARFGLKCVVYMGAVDVARQAPNVFRMKMLGAEVVPVESGTKTLKDAMNEALRDWVTNVADTFYCIGTVAGPHPYPAMVRDFQSVIGRETREQMIAQEGRIPDSLVACIGGGSNAMGLFHPFLDDREVEIFGVEAAGHGVQSGLHAASLTGGKPGVLHGNRTYLLMDGDGQIADAHSISAGLDYPGIGPEHAWLHEMGRVTYLSATDSETLEAFKLCSMLEGIIPALEPAHALSKVLELAPQRPAEHLMVMNMSGRGDKDIPQVAEIFGTKI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PAX_I61A1
Sequence: MEDFVRQCFNPMIVELAEKTMKEYGENPKIETNKFAAICTHMEVCFMYSDFHFINERGESIIVEPGDSNALLKHRFEIIEGRDRNVAWTVVNSICNTTGVGKPKFLPDLYDYKEDRFIEIGVTRREVHVYYLEKANKIKSEETHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLRSQGQCEGLPTKVSHQTSPVLKTLEPMWMDSSRMATLRASFPKCLEK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: GRP3S_ARATH
Sequence: MASKTLLLLGLFAFLFIVSEMAAAGTVKSESEETVKPEQHGGGFGDNGGGRYQGGGGHGGHGGGGYQGGGGRYQGGGGRQGGGGSYCRHGCCYKGYHGCSRCCSYAGEAVQTQSGH
What is the function of this protein?
Regulates the function of the receptor protein kinase WAK1.
What are the official names of this protein?
Glycine-rich protein 3 short isoform.
What is the protein family that this protein belongs to?
Belongs to the GRP family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: GRPE_BRASO
Sequence: MTDPDLHQNDPENPAQASEPVVSKPYIMPDDPETGSAEAYAKEAAEARDKMLRTLAEMENLRKRTAREVADARMYGITGFARDVLDIADNLQRALDAVPAETRANADAGLKSLIEGVELTERSLLNTLEKNGVKKFDPTGQKFDPNFQQAMYEVPDPSVPSGTVVQVVQAGFMIGERVLRPALVGVSKGGAKAAPAASNDQSNSAA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6M_ARTSF
Sequence: MLGSIVVISMFMLLMNHPLAFTLSLFVQTLLICVMLKNVSLWISLILFLIFLGGILVMFIYVSSLSANEKFAVDLTSFMWVVPTIVLSFLVLNKNFMFMSPSSGYLYPTDFVIINFNVNSLTMLAYSFMVVYLFLALLLVIDFLNSNKKPLRSMI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: ACOX2_RABIT
Sequence: MGIPVHRVSLGDAWSSRMHPDMESERCAQSFSVERLTNILDGGAQHTALRRKVESIIHGNPQFSSKDNYFMSQNELYEAATRKRYHLQKIAQRMGWTEEGRELEYAHRALSADLNLNLQGIFLKALRSLGSEEQIAKWEPLGKTFQIISTYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTVTATKWWPGDLGRSATHALILAQLICSGARRGMHAFIVPVRSLQDHTPLPGITIGDIGPKMGLQHIDNGFLKMDHVRVPRENMLSRFAQVLPDGAYIKLGTAQSNYLGMLVTRVHLLLGAILSPLQKACVIATRYSVIRHQCRLRPSDPEVKILEHQTQQQKLFPQLAMCYAFHFLATGLLEFFQQAYKNILDRDFTLLPELHALSTGTKAMMSDFCTQGAEQCRRACGGHGYSKLSGLPSLVTSVTASCTYEGENTVLYLQVARFLVKSCLQAQGFPGSTSQRSLPRSVSYLALPDLARCPAQTAADFFCPALYTAAWAHVAARLTKDSVHHLQALRQSGADEHEAWNQTTIIHLQAAKAHCYYISVKSFKEALEKLENEPAIQQVLKRLCDLHALHGILTNSGDFLHDGFLSGAQVDMARTAYMDLLPLIRKDAILLTDAFDFTDQCLNSALGCYDGNVYERLFEWAQRSPTNTQENPAYKKYIQPLLQSWRSNL
What is the function of this protein?
Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids (PubMed:9218493).  Capable of oxidizing short as well as long chain 2-methyl branched fatty acids (By similarity).
What are the official names of this protein?
Peroxisomal acyl-coenzyme A oxidase 2, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase, Trihydroxycoprostanoyl-CoA oxidase, THCA-CoA oxidase, THCCox.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA oxidase family.
What are the subcellular locations of this protein?
Peroxisome.