PharMolix/UniProtQA huggingface dataset:
Protein: PANB_THEPX
Sequence: MEEKVSTLTLRKFKKEGRKITALTAYDFPTAKILDNCGIDMILVGDSLGMVVLGYESTIPVTMEDMIHHTKAVSRAVNRAFIVADMPFMSYHISKEQAMTNAARLIAEGGAHAVKLEGGEEIASIVKAIVDAGIPVVGHLGLTPQSVHQLGGYKVQGKEKEQAKKIFNDAKVLEQAGICALVLESIPMELAKNITENISVPTIGIGAGPYCDGQILVTHDMLGITQGHRPKFVKQYADIEKIMIDGINAYIKEVQQVLFPDEEHSFTLEKRENK
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR5_BOVIN
Sequence: MATGEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
What is the function of this protein?
Contributes to histone modification (By similarity).  May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4' (By similarity).  As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3 (By similarity).  H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (By similarity).  As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (By similarity).  May regulate osteoblasts differentiation (By similarity).  In association with RBBP5 and ASH2L, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (By similarity).
What are the official names of this protein?
WD repeat-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR5/wds family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OCCP_RHIRD
Sequence: MPNPVRPAVQLKDIRKNFGNLEVLHGVSLSANEGEVISILGSSGSGKSTLLRCVNMLEVPNAGSVAIMGEEIALEHRAGRLARPKDLKQVNRLRERAAMVFQGFNLWSHQTILQNVMEAPVHVQGRDRKACRDEAEALLERVGIASKRDAYPSELSGGQQQRAAIARALAMRPDVMLFDEPTSALDPELVGEVLKVMRDLAAEGRTMLIVTHEMDFARDVSSRTVFLHQGVIAEEGPSSEMFAHPRTDRFRQFLRRDGGTSH
What is the function of this protein?
Component of the octopine active transport system probably consisting of four subunits: Q, M, P and T.
What are the official names of this protein?
Octopine permease ATP-binding protein P.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YAT2_SYNP1
Sequence: MGGRLQLWRFLVGVKLTKLLIGHGFLEAVNDAGAVAIAAIAKAGRSLRRKLRFTVSHKGSNRFWWVSIGCICYSGQRPKA
What are the official names of this protein?
Uncharacterized 8.8 kDa protein in atpI 5'region, URF2.
Protein: QUEF_NITEU
Sequence: MTTQPSKQLETFENPVQTRDYRIHMEIPEFTCLCPKTGQPDFARLTLDYIPDKKCIELKSLKLYIWSYRDEGAFHEAVTNRILDDLVAAMKPRFIRLTSKFYVRGGIFTNVVAEHRKKGWQPQPPVLLEVFEQQFNTHG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTN3A_XENLA
Sequence: MAETSGPQSSHISSSSVGEKGSGCAVRDLLYWRDVKQSGMVFGGTMVLLLSLAAFSIISVISYLVLSLLTVTISYRVYKSVLQAVQKTDEGHPFKPLLEKDITLSSDSFQKALTASLAHVNHALKYIVRLFLVDDLVDSLKLALLMWLMTYVGAVFNGITLLILGVLLTFTAPIVYEKYKVQIDHYVSLVHSQVKSITEKIQAKLPGALKKKSE
What is the function of this protein?
May be involved in membrane trafficking in the early secretory pathway.
What are the official names of this protein?
Reticulon-3-A, RTN3.1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: DDX4_XENLA
Sequence: MEENWDTEIETEKPTYVPNFSTLETENTDNYSAYSNNDINNQNYDSERSFGNRGGYRSERSRPSNFNRGSRTERGRGRGFGTNRNDNYSSERDVFGDDERDQRRGFPGRGGYNGNEDGQKPNAFRGRGGFRNENEQRRGFGERGGFRSENGQRNFDNRGDFGNSGEEEDRPRSYGRGGFNNSDTGGRGRRGGRGGGSQYGGYKGRNEEVGVESGKSQEEGNEKDEKPKKVTYIPPPPPDGEDNIFRQYQSGINFDKYDEILVDVTGKDVPPAILTFEEANLCETLRRNVARAGYVKLTPVQKHSIPIIMAGRDLMACAQTGSGKTAAFLLPILSYMMNEGITASQYLQLQEPEAIIIAPTRELINQIYLDARKFSYGTCVRPVVVYGGIQPVHAMRDVEKGCNILCATPGRLLDIVSKEKIGLSKLRYLVLDEADRMLDMGFAPEIEKLMTKPGMPTKEKRQTLMFSATYPEEIRRLASNYLKSEHLFVVVGLVGGACSDVAQTVLEMRENGKMEKLLEILKSSEKERTMIFVNTKKKADFIAGYLCQEKFSSTSIHGDREQYQRESALWDFRTGKCTVIVCTAVAARGLDIENVQHVINYDVPKEVDEYVHRIGRTGRCGNTGKATSFFNVQDDHVIARPLVKILTDAHQEVPAWLEEIAFGGHGALNSFYAADSMGEQAGGNAVTTPSFAQEEEASWD
What is the function of this protein?
Probable ATP-dependent RNA helicase required during spermatogenesis (PubMed:14706067, PubMed:9338598).  Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX4, DEAD box protein 4, Vasa homolog, Vasa-like protein, xVLG1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX4/VASA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the cytoplasm of somatic cells, primordial germ cells (PGCs) and most adult germline cells, except spermatogonia where it is located in the nucleus (PubMed:8150200). Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis (By similarity).
Protein: TRBM_MOUSE
Sequence: MLGIFFLGVLAPASLGLSALAKLQPTGSQCVEHECFALFQGPATFLDASQACQRLQGHLMTVRSSVAADVISLLLSQSSMDLGPWIGLQLPQGCDDPVHLGPLRGFQWVTGDNHTSYSRWARPNDQTAPLCGPLCVTVSTATEAAPGEPAWEEKPCETETQGFLCEFYFTASCRPLTVNTRDPEAAHISSTYNTPFGVSGADFQTLPVGSSAAVEPLGLELVCRAPPGTSEGHWAWEATGAWNCSVENGGCEYLCNRSTNEPRCLCPRDMDLQADGRSCARPVVQSCNELCEHFCVSNAEVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCVNTKGGFECFCYDGYELVDGECVELLDPCFGSNCEFQCQPVSPTDYRCICAPGFAPKPDEPHKCEMFCNETSCPADCDPNSPTVCECPEGFILDEGSVCTDIDECSQGECFTSECRNFPGSYECICGPDTALAGQISKDCDPIPVREDTKEEEGSGEPPVSPTPGSPTGPPSARPVHSGVLIGISIASLSLVVALLALLCHLRKKQGAARAELEYKCASSAKEVVLQHVRTDRTLQKF
What is the function of this protein?
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin.  This complex is responsible for the conversion of protein C to the activated protein C (protein Ca).  Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
What are the official names of this protein?
Thrombomodulin, TM, Fetomodulin.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ENOA_PONAB
Sequence: MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNRIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAK
What is the function of this protein?
Glycolytic enzyme the catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate.  In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses.  May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons.  Stimulates immunoglobulin production.
What are the official names of this protein?
Alpha-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 1, Non-neural enolase, NNE.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M-band.
Protein: RUVB_DESHD
Sequence: MEERMITPQQLPGDQEGEVLRPHRLADYIGQTKVKDNLQIFIQAALARGEALDHVLLYGPPGLGKTTLANIIATEMEVNIRTTSGPAIERPGDLAAILTSLEPRDVLFIDEIHRLSRTTEEILYSAMEDGCLDIVIGKGPSARSIRLTLPPFTLVGATTRAGQLASPLRDRFGVISRLEFYEVEDLIRIITRAAGILNLQITLEGASEIARRSRGTPRVANRLLKRVRDYAQVWEDGRVTQELAGKSLDRLEVDPAGLDRIDQKCLLTIIQMFAGGPVGLETLSATIGEEAETIEDVVEPYLLQQGFIQRTPRGRVATVRAYQHLNIPVNSSHQEGGQGDSLFDAAED
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MED6_CRYNB
Sequence: MAQQVEEIEQDLSHIHWSWPEAIAANPARSLATPDLAMDYFAYSPFWDAKSNNNVLRTQRRIENPAYGHAEEKVELNAFMSGFEYVVAHSQPPDLFVIHRREVESSGKRDRVTGAWFILHEKIYQCPTLFDVMSTRLKNATSLISKTLSTLSENRPPANPRTTTLWRSIPSVTSNQPDGTQPSSLDQAEKPDEGKKDDSLNGSSPLDGSDGKASPAGPDWHLFHALQATRASLVSLETLAKTPTQTTDPREELNNIEIAMDNQFGGQNQSLSGKGPNVKGGAAAVKNISVPFVPKHSAGHATSTTGLTPSIWGGSASLGVSTAAVPAREAGGSPLKWPGGDKSAPIAGATLAGQTGR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 6, Mediator complex subunit 6.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y531_PASMU
Sequence: MQTLLIIRGHSGSGKSTFALQKMAEFKQNFTEGVLFHVENDHFLRENGEYHWTVERFQQAKQLAQQQLADALNYCVENPQHDVCIVLSNVGGNAKEIEKVVARATSYGLHTEVYRLQNFFPNTHGVDAQVVYEMYLHLCDQPVQNEILLPPIQPMTKAICREIKKLQAQKRKNRYTKKM
What are the official names of this protein?
Uncharacterized protein PM0531.
Protein: DJ1B_DROME
Sequence: MSKSALVILAPGAEEMEFIIAADVLRRAGIKVTVAGLNGGEAVKCSRDVQILPDTSLAQVASDKFDVVVLPGGLGGSNAMGESSLVGDLLRSQESGGGLIAAICAAPTVLAKHGVASGKSLTSYPSMKPQLVNNYSYVDDKTVVKDGNLITSRGPGTAYEFALKIAEELAGKEKVQEVAKGLLVAYN
What is the function of this protein?
Plays an important role in cell protection against oxidative stress and cell death by acting as a oxidative stress sensor (PubMed:16139214, PubMed:16203113, PubMed:16894167, PubMed:20457924).  Does not play a role in methylglyoxal detoxification (PubMed:27903648).  Plays a role in mitochondrial function together with Pink1 (PubMed:20457924).  In motor neurons regulates structural synaptic plasticity of locomotor behavior as part of the PTEN-phosphatidylinositol 3-kinase pathway in response to oxygen species (ROS) levels (PubMed:30540251).
What are the official names of this protein?
Protein dj-1beta.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm. Nucleus.
Protein: RL1_LEPBL
Sequence: MQRGKKYKALKEKVDSTKFFNIDQAVELAKSTSYTKFDGTVEIATKVNYKSLQNIRGTISLPHGNGKKVRVLVFCKGDKQNDAKAAGAEFVGDMDLIEKVAGGWTDFDACVATPDMMKDVGKLGPILGRKGLMPKPKAGTVTTDVAKAVNELKSGRVEYRPDKGGVVHLGVGKVSFDNAKLVENIRTVVQTLMRDKPSDAKGDYLKTFSVSPTMGVGVKVDVKELVNTSI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CH602_SYNSC
Sequence: MAKRIIYNENARRALEKGIDILCEAVAVTLGPKGRNVVLEKKFGAPQIINDGVTIAKEIELEDHIENTGVALIRQAASKTNDAAGDGTTTATVLAHAMVKAGLRNVAAGANAITLKKGIDKASDFLVSKIKEMAKPIADSNAIAQVGTISAGNDEEVGKMIADAMDKVGKEGVISLEEGKSMETELEVTEGMRFDKGYISPYFATDTERMEAVLDEPYILLTDKKIGLVQDLVPVLEQIARTGKPLLIIAEDIEKEALATLVVNRLRGVLNVAAVKAPGFGDRRKAMLEDMAVLTNGQLITEDAGLKLENAKLEMLGTARRITINKDTTTIVAEGNEAAVGARCEQIKKQMDETDSTYDKEKLQERLAKLAGGVAVVKVGAATETEMKDKKLRLEDAINATKAAVEEGIVPGGGTTLAHLAPALEQWAASSLSGEELIGANIVAAALTAPLMRIAENAGANGAVVAENVKARAGAEGFNAASGEYVDMLAAGIVDPAKVTRSGLQNAASIAGMVLTTECIVADLPEKKEAAPAGGGMGGGDFDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_LISMC
Sequence: MSEKQVFSTEWAGKTLSVEVGQLAKQASGAALIRYGDTVVLTAAVGSKKPRPGDFFPLTVNYEEKMYSVGKVPGGFLKREGRPSDRATLTARLIDRPIRPLFAEGFRNEVQITSTVFSVDQDCSPEMAAMLGSSVALVISDIPFEGPIAGVDVGRIDGKYVINPTIEQAEKSDISLTVAGTYDAINMVEAGAKEVSEEAMLEAIMFGHEEIKRLCEFQQQIIAAVGKEKREIELFVSDPELEAEVKAASEGKMKAAIKTEEKKAREAAIEDVKEEILESYKAKELENEAEILSEVAHILEMIEKDEMRRLISQDKIRPDGRKVNEIRPLSSEVGMLPRVHGSGLFTRGQTQALSVCTLAPLREHQIIDGLGTEEYKRFMHHYNFPQFSVGETGPRRAPGRREIGHGALGERALQYVIPSEEEFPYTIRLVSEVLESNGSSSQASICGSTLAMLDAGVPIKAPVAGIAMGLVKLGDDYTILSDIQGMEDHFGDMDFKVAGTKDGITALQMDIKIDGLSRQILDEALTQAKEGRLHILEHLTSTISAPREELSAYAPKIITLNIKPEKIKDVIGPGGKQINAIIDETGVKIDIEQDGTVYIASQDQAMNRKAIAIIEDIVREVEVGEVYTGKVRRIEKFGAFVELFKGTDGLVHISELAHERVGKVEDILKLGDEVTVKVIEVDQQGRVNLSRKALLEKKEQPEGDKKPQAEKKFYPKTKKPESK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_VIBPA
Sequence: MSLLEFFRPQKKTSASLAKERLQIIVAERRSQNDPAPSYLPQLKEDILKVISKYVDIDPNMVDLTFEHKDDDISVLELNVKLPDDEK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: ORN_MOUSE
Sequence: MLGVSLGARLLRGVGGRRGQFGARGVSEGSAAMAAGESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPNLIIKQPDELLDSMSDWCKEHHGKSGLTKAVKESTVTLQQAEYEFLSFVRQQTPPGLCPLAGNSVHADKKFLDKHMPQFMKHLHYRIIDVSTVKELCRRWYPEDYEFAPKKAASHRALDDISESIKELQFYRNNIFKKKTDEKKRKIIENGETEKPVS
What is the function of this protein?
3'-to-5'exoribonuclease that preferentially degrades DNA and RNA oligonucleotides composed of only two nucleotides (PubMed:31588022).  Binds and degrades longer oligonucleotides with a lower affinity (By similarity).  Plays dual roles in mitochondria, scavenging nanoRNAs (small RNA oligonucleotides of <5 nucleotides) that are produced by the degradosome and clearing short RNAs that are generated by RNA processing (By similarity).  Essential for correct initiation of mitochondrial transcription, degrading mitochondrial RNA dinucleotides to prevent RNA-primed transcription at non-canonical sites in the mitochondrial genome (PubMed:31588022).  Essential for embryonic development (PubMed:31588022).
What are the official names of this protein?
Oligoribonuclease, mitochondrial, RNA exonuclease 2 homolog, Small fragment nuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Mitochondrion matrix. Mitochondrion. Cytoplasm. Nucleus.
Protein: ATPI_DAUCA
Sequence: MNVLSCSINKLNGLYDISGVEVGQHFYWKIGGFQVHGQVLITSWVVIAILLGSATLAVRNPQTIPTSGQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALLTSVAYFYAGISKKGLGYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RSMJ_ECOSM
Sequence: MKICLIDETGTGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT11_PROWI
Sequence: MLVKKSQISRKFIEKKSGIVHIQSTTNNTLITLTDLEGNTQFFVSAGTLGFKNSRKSTVYASGAAAEALASKAFNEGYRTIIVKIKGLGYGKKSAIRGLQKSNLVIKQIQEVTPIAHNGCRPPKKRRV
What are the official names of this protein?
Ribosomal protein S11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARGI_BREBE
Sequence: MNKNMSIVGVPMDLGADRRGVDMGPSAIRYAGVVARLEKMGFNIEDRGDIFVTLPHHFTETENHKYLDEVVEANEKLANVVSDIMTAGRFPLVLGGDHSIALGTIAGVAKHVKNLGVICLDAHGDLNTGATSPSGNIHGMPLAASLGYGHERLTNIGGYTPKVKAENVVIIGARDLDQGERELIKRIGMKVFTMHEIDKLGMARVMDEAIAHVSKNTDGVHLSLDLDGLDPHDAPGVGTPVIGGISYREGHVSLEMLADADILCSAEFVEVNPILDRENMTARVAVALMSSVFGDKLL
What are the official names of this protein?
Arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: KCTD5_RAT
Sequence: MAENHCELLPPAPSGLGAGLGGGLCRRCSAGIGALAQRPSGVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINRDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQMPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTTSEPSEKAKILQERGSRM
What is the function of this protein?
Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (By similarity).  Does not affect the function of Kv channel Kv2. 1/KCNB1, Kv1. 2/KCNA2, Kv4. 2/KCND2 and Kv3. 4/KCNC4 (By similarity).
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD5.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, translocated to the nucleus upon interaction with Rep proteins.
Protein: 3BHS6_MOUSE
Sequence: MPGWSCLVTGAGGFLGQRIVQLLMQEKDLEEIRVLDKFFRPETREQFFNLDTNIKVTVLEGDILDTQYLRKACQGISVVIHTAAVIDVTGVIPRQTILDVNLKGTQNLLEACIQASVPAFIFSSSVDVAGPNSYKEIILNGNEEEHHESIWSDPYPYSKKMAEKAVLAANGSMLKIGGTLHTCALRPMYIYGERSPFISNTIITALKNKNILGCTGKFSTANPVYVGNVAWAHILAARGLRDPKKSPNIQGEFYYISDDTPHQSYDDLNYTLSKEWGFCPDSSWSLPVPLLYWLAFMLETVSFLLSPIYRFIPPFNRHLVTLTGSTFTFSYKKAQRDLGYEPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ
What is the function of this protein?
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids.  The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.  May be involved in local production of progesterone.
What are the official names of this protein?
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 6, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type VI, 3-beta-HSD VI.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Protein: MGSA_BACVZ
Sequence: MKIALIAHDKKKQDMVQFTTAYKDILSHHELYATGTTGLKIQEATGLSVERFQSGPLGGDQQIGALIAANALDLVIFLRDPLTAQPHEPDVSALIRLCDVYAIPLATNMGTAEILVRTLDGGAFDFRNLVRGGEPNV
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: GATA_LIGS1
Sequence: MDYFKNDLASIHDDLVNKKYSVEELTKSTFDNIKKVDKEIEAFLKLDEERALEKARKIDERGVKADSILDGIGIGIKDNIVTKDLTTTAASKMLENFEPIYNATVMDKLNDAGMITVGKLNMDEFAMGSSTENSAFKITKNVWDTTKVPGGSSGGSAAAVASGQVLASLGSDTGGSIRQPAAFNGIVGVKPTYGRVSRYGLIAFASSLDQIGPLTRTVKDNALVLNAISGHDAHDFTSSSREVPDFTKGIEDGVKGMRIAVPKEYFGEGVDEDVAKAVKDAVKTFESLGATVDEISLPHSKYGVPVYYIIASSEASSNLQRYDGIRYGFRAKDVKNLEDVYVRSRSEGFGDEVKRRIMLGTFSLSAGSYDAFFKKAAQVRTLICQDFENVYKDYDLILAPTSPTTAYGIGEEINDPVTMYMNDILTIPVNLAGLPGMSLPAGFSNGLPIGLQLIAPRFAESTMYRAGYAFEQSTDFHKAIPTLGGQN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.