PharMolix/UniProtQA huggingface dataset:
Protein: HIFA1_HAEIF
Sequence: MKKTLLGSLILLAFAGNVQAAANADTKGTVTFFGKVVENTCQVKTDHKNRSVVLNDVGKNSLKDKGNTAMPTPFTITLQNCNLTAANSSTNKANKVGLYFYSWENADKENNFTLKNKTSTSNDFATMVNIQLMESDGTKEIKVVGKETEDFVHKNATGAGVALTQTHPDNDHISGSTQLTGVTGDLPLHFIAQYYSLGSTTAGKVQSSVDFQIAYE
What is the function of this protein?
Mediates adherence to oropharyngeal epithelial cells.  Helps the airway colonization process.
What are the official names of this protein?
Major fimbrial subunit, Major pilin.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: ARMC7_MOUSE
Sequence: MAQKPKIDPHVGRLGYLQALVTEFQETESQDAKEQVLANLANFAYDPGNYQYLRQLQVLDLFLDSLSEENETLIKFAIGGLCNLCADKANKEHVLQAGGLPLIIGCLSSPDEETVLSAVTTLMYLSSPGSRSHPELTSLPVVQCMLRFSISASTRLRNLAQIFLEDFCSPSQVAEAHSQQAHSALGIPLPKTEAPQQP
What is the function of this protein?
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
Armadillo repeat-containing protein 7.
Protein: Y199_MYCPN
Sequence: MKFKLFLGSSFFGVATLLIACGTGRFDQIDDGKIKLAVVTSPSAASSLQTLLDQYNNTKAPADYPVEVVSLDSTGSYTKGKFDTQKRLAAKDKNNFYNLTFNYPDLVSSLAINGMELNLDGVNVSNFEQSFLDFNKNISGVRKPGIYALPATMSGEVLVLNGPVLHYILNSAKKKDGTESKIKTAQLKTASTQAEVKGTMTMASDEQTTKLWTNIQNAAKENAANGTTEKAEKTVSASSLQLKNTNKTTEGTLKIGTDDNTKNLWKKIEDAAKTNGEKGNEKQEATQSNASASLVKLDQKNTSQDKTQNTQTSDDEIKKSWGEYKEVEGGLKGYEFKADVFESWEKLNDFAVRVAKSFSKVSEEKKSGSDIQGVFGIGSLENALYTASFAAGGGDYNNFLFNIKKGRADFSNFFNHNSKTFQSLRDIFNSFKPLIDQKGLISNKHFDTPVNNYAKFHQLAFYVSSTARFPYSFAKDNVKRLIIGKRELEVNPKSMFAIKKENGNNGNSNLLGKVALDNNKSIELYENNIPNGKTDAILIKNQTLISALKNPKQTKSSQRSSQSTNTQNDAICYLAFNSKIRPDDKDIFLLDKFGEKFVTAIVNFEEKTEVKINTLQEKEAVVLPAPQKFKPTDPKSVALVQGPSLIGIHANANEDRSTIKFLNWYLNAEVDWKDGEKKTPAEYLAEKASYLLPFKKVLEKSKQNIKATSKEGEQNQGKKGDGAQNQGKKGDGAQNGKNDKAKHNGFCRYCRQPIFKRFCR
What are the official names of this protein?
Uncharacterized lipoprotein MPN_199.
What is the protein family that this protein belongs to?
Belongs to the MG185/MG260 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GLRX2_CAMPS
Sequence: MKNVLIIFGKPYCSICENVSEAVEELKSEYDILHVDILSFFLKDGDSSMLGDVKRGTLIGNFAAHLSNYIVSIFKYNPQTKQMAFVDINKSLDFTKTDKSLVNLEILKSEIEKANYGVWPPVTE
What is the function of this protein?
Glutaredoxin necessary for virion morphogenesis and virus replication.  Functions as a thiol-disulfide transfer protein between membrane-associated OPG128 and substrates OPG095 or OPG053.  The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves oxidation of OPG072, OPG128 and OPG088.  Exhibit thioltransferase and dehydroascorbate reductase activities in vitro.
What are the official names of this protein?
Glutaredoxin-2.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: LEUC_ANADF
Sequence: MSATDPRPARTLFEKVWDAHVVRAETPETPAVLYIDLHLMHEVTSPQAFSMLRERGLKVRRPDRTLATTDHSTPTLPRLPDGRWPFFDAQNEAQVAQIEKNARDFGVELHGLGDPQQGVVHVFGPEMGATQPGMTVVCGDSHTATHGAFGALAFGIGTSEVGHVLATQCLLQRKPRSLAIRVDGALQPGVTAKDLILAIIAQIGVGGGTGHVMEFTGPAVRALTMEGRMTLCNMAIEGGARAGMIAPDDVTFQWLAGKPRVPQGAAFDAAVARWRELPTDAGARYDREVTVDVSRLEPMVTFGTNPAQGIPVTGRIPDPGAEKDPSARATLESALRYMALAPGKPILGQKVDVVFVGSCTNGRLEDLREAARVMRGRKVKTRTLVVAGSHAVKKAAEAEGLDRIFREAGAEWREPGCSMCLAMNGDMLEPGQYCVSTSNRNFEGRQGPGGRTLLASPATAAAAAVSGAVADPRRLVEG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: DAPB_STRP7
Sequence: MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKTAELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLP_BPPM6
Sequence: MIVNNTPVETYELNGVPILVKREDLCAPLPGPSFSKIRGVVAHIKNRPETTIGCLDTYHSKAGWAVAYVCQQLGKQAVDYWPRFKRDGAADAPRVQQQHARQLGADLVDIPAGRSAILYHTAKKHLRENYHDSYLMPNALKLPESITENAAEAVRTAPHLPDSGTLVISISSGTVAAGVLKGFEEAGLLRNYNVILHMGYSRSQDATREYIEKAAGLTLGDRIKFIDEGYGYADAARDASAPFPCNPFYDLKAWKWLSNPTNLETILDGPIVFWNIGE
What is the function of this protein?
Converts 5-Calpha-glycinylthymidine (Calpha-GlyT) into 5-aminoethyl-2'-deoxyuridine (5-NedU) as a step in the pathway leading to thymidine hypermodifications in the viral genome (PubMed:34522950).  As a final result of the pathway of hypermodification, 5-aminoethyl-2'-deoxyuridine (5-NedU) substitutes for about 30% of thymidines in the viral DNA (PubMed:34522950, PubMed:29555775).  These modifications probably prevent degradation of viral genome by the host restriction-modification antiviral defense system (PubMed:34522950).
What are the official names of this protein?
Glycyl-dTMP PLP-dependent decarboxylase, gp52.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal-phosphate-dependent aminodecarboxylase family.
Protein: HIS81_TRIV2
Sequence: MTNYFRSNVEAMASYVPGEQPPRGTQVIKLNSNENPYPPSPAALAALQDIDGEWLRRYPEPLGGEFREAASKVLGVPSDWLIVGNGSDEILSIVIRACTEPGRKVVYPMPTYVLYRTLTQMQAADILEIPYQENNVLPVAELIAADGAVTFIASPNSPSGHIVPNDDLRKLASELSGVLVIDEAYVDFAEESALDLVQEYENVILIRTLSKGYSLAGLRLGFGVGNPKLLDGLFKVKDSYNIDAIACKVAAVAITDQAYKNSCVAKVKASRTQLTKDLKQLGFHVWDSHGNFLLTKPPEGNAEYLYEKLKEQKILIRYFQQPGLEDKLRITVGTDEQNHILVRALRDLLR
What are the official names of this protein?
Histidinol-phosphate aminotransferase 1, Imidazole acetol-phosphate transaminase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RL13_THEVO
Sequence: MKIIDASNTVYGRLSAYVAKQLLNGEEVVIVNASKAVITGDRKFIIDKFKQRLDIGSVRKGPYYPKTPENILRRSIGDMLPKKITRGKEALSRCKVYRNLPKNVSSEKIEKVDDVMTDKVVGIITLEELSKELGGM
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: HCFC1_HUMAN
Sequence: MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPPSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKPANKRPMSSPEMKSAPKKSKADGQ
What is the function of this protein?
(Microbial infection) In case of human herpes simplex virus (HSV) infection, HCFC1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and POU2F1 thereby enabling the transcription of the viral immediate early genes.
What are the official names of this protein?
Host cell factor 1, HCF, HCF-1, C1 factor, CFF, VCAF, VP16 accessory protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=HCFC1R1 modulates its subcellular localization and overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm (PubMed:12235138). Non- processed HCFC1 associates with chromatin. Colocalizes with CREB3 and CANX in the ER.
Protein: Y1887_ARATH
Sequence: MPSRPNPTRPKLFHNRTKTLFLILTISSSLVIFFAILYFIYHLWISLLNRSRTIPFDVAAASPLKLQLFTYKELKLATNDFDESNVIGKGGSGTVFRGITRDGKLFAVKRLDNLSIQTETEFQNELQILGGLKSSFLVTLLGYCVEKNHRFLIYEYMPNKSLQELLFNEDGDSCLNWERRFGIILDVAKALEFMHFGCDPPVIHGDIKPSNVLLDSEFRAKISDFGLSRVKVEGGYGVDLFSQELSGNFGGESTPQTAIGTPTHHEVDFALALQASSSSKNSRTSRNIKEMSLNSMSLAMDGETKGKEVSNDVVLSCEDHEFDQGKEMNLLSPNSVLDLGKGSKQWGRDWWWKQEGSGELCSKDYVREWIGSQIDTANPDWDDDKKVITTPELGVSTRTIDKAEHRDESGLNESRFDTLEEKFAKEEISERKNKRSKNKKKKHRNMEEWWKEEEHQEEMNNKKKIGVLRIKFKNHLKFPHFRYCFRQKGENSVHDREGEAAGEFSFRRGWRRKSNSSSKKKKKNNNGSMGSEMWSGDLFSRELSSTTSMRGTLCYIAPEYGGGCCYLMEKGDIYSFGVLILVIVSGRRPLHVLASPMKLEKANLVSWCRQLAQSGNVLELVDEKLKDGYNKEEAGLCINLALACLQKAPELRPDVSEVVRILRGEMDISSTAFEFSPSPPGKVYGSRSKRRS
What are the official names of this protein?
Putative receptor-like protein kinase At1g80870.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ALR_POLNA
Sequence: MPRPILATIHLAALSHNLARVRTAAPDAKVWAVVKANAYGHGIERVFDALRSADGFALLDLDEARRLRALDWRGPILLLEGCFEARDLELCSRLGLWHTIHCQEQIDMLAAHKTQLPHRVFLKMNTGMNRLGFTPERFRAAWIRLNALPQVDEISLMQHFPDADGPKGITAQLQAFDAVTHDLPGERTLSNSAAILRHTGALAGRSDWVRPGIVLYGSAPDFPEHSASDWELQPTMTLSSRIIGLQTLAAGDTVGYGSSFVAEGPMRIGVVACGYADGYPRHCPTGTPVLVNGVRTRMVGRVSMDMITVDLTPVPRAGMGSEVTLWGRASKGGAMLPIDEVARAAGTVGYELMCAVAPRVPVAVD
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PCKA_ESCF3
Sequence: MRVNKSLTPQDLMAYGINDVQDIVYNPSYDLLFQEELDPNLKGYERGVLTNLGAVAVDTGVFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETWQHLKGLVTNQLSGKRLFVVDAFCGANADTRLSVRFITEVAWQAHFVKNMFIRPTDEELVDFEPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASSEQWQEKAETLAKLFIDNFDKYTDTPAGAALVEAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_CHLT2
Sequence: MEQTLSIIKPDSVGKAHIGEIIAIFEKSGLRIAAMKMVHLSVKEAEGFYVVHKERPFFQELVDFMISGPVVVMVLQGENAVARNRELMGATNPKEAAEGSIRALFGESIGVNAVHGSDSLENAAIEVSYFFAKTEVVNSVA
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLN_TETOB
Sequence: MTILLEEKEKLTFECETGNYHTFCPISCVSWLYQKIEDSFFLVIGTKTCGYFLQNALGVMIFAEPRYAMAELEESDISAKLNDYKELKRLCFQIKEDRNPSVIVWIGTCTTEIIKMDLEGMAPELERELGIPIVVARANGLDYAFTQGEDTVLAAMAQRCPSLPLNVEEKSQNSLFNQSSNSPENLKTLNTKKDTFQNSTENSKTFSAEKKKTQNPFEFFKSLEEFFPSFSIQNNKKETILSKNSFVPFVEVEKNMYPLESSENSKAESFYHLLREGEQTNQNSELVKPKLVLFGSLPNTVATQLKLELNRQGIEISGWLPSTRYSDLPILDTNTYVCGVNPFLSRTATTLMRRRKCKLISAPFPIGPDGTKAWIEKICSIYGKKPIGLEERETKIWEGLEDSLKLVRGKSVFFMGDNLLEISLARFLIRCGMIVYEIGIPYLDQRFQAAELALLEKTCFEMNVPVPRIVEKPDNYYQISRIRELQPDLVITGMAHANPLEARNITTKWSVEFTFAQIHGFTNAREILDLVTRPLRRNQNINSFSEFFGSTTSTFVQNQF
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUOD_CAMHC
Sequence: MQDPNKLRPFFENVEFNREGSNMILNFGPQHPSAHGQLKLVLEVDGEKIIKARPGIGYMHRGVEKMAENMIYQEFVPVTDRVDYIAAGSNNYGFCATVEKLCGIDVPRRAQIIRTMLLELNRIASHLLFLGTHALDIGAMTVFLYTFREREYVLDLIEKYSGARLTHHNVKIGGMFVDLPDGWLDELLAFCEKFPRDIADYEALLDTNRIWLLRTQNVGVITKEQALSCGCSGVMLRASGYKWDIRKEEPYLIYDELDFDVPYAEAGDCYARYKCYVQEMRESVKILTQCVPLYKASEPKILADSPEFVSAGKEQLMSQNYSLMQHFVLITQGLKPPEGEIYLATESPKGELGFYIYSVGESSPYRLKIRCPSFWHCAIYEEIMPGQYIADVTAIIGSSNIILGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HFQ_LEPIC
Sequence: MSAKNNIQDQLLNTARKDKLDLTIYLLNGVPLKGKVVSFDNFTIVLEQENKQSLVYKHAISTIIPAKIIKLYTEEAKDNKDAAQG
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RS11_SHELP
Sequence: MAKVPSRSTRKRVRKQVADGMAHIHASFNNTIITITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGVAAQDYGVKNLEVFVKGPGPGRESAIRALNAVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DBH_STRPQ
Sequence: MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQLIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.  Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation (By similarity).
What are the official names of this protein?
DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: DAPH_GEOSW
Sequence: MKMMDANEIISFIQNSKKSTPVKVYIKGSLEGIDFGPSAKTFITGNTGVVFGEWQEIQAALEANKEKIDDYVIENDRRNSAIPLLDLKGVKARIEPGAIIRDQVEIGDNAVIMMGAVINIGAVVGEGTMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSAKPVIVEDDVVIGANAVILEGVTVGKGAVVAAGAIVVEDVPPYTVVAGVPARVIKQIDEKTRAKTEIKQELRQL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: RS3_BIFAA
Sequence: MGQKINPFGYRLGITENHRSKWFSDSNKVGERYRDFVLEDDAIRKAMSKDLERAGVSRIVIERTRDRVRVDIHTARPGIVIGRRGAEAERVRAKLEKLTGKQVQLNIFEVKNAALDAQLVAQGIAEQLTNRVTFRRAMRKAQQDAMRAGAKGIRIKLSGRLGGAEMSRSEFYREGCVPLQTLRALIDYGFFEAKTTYGRIGVKVWIYKGDMTEREFEEQQAQQSNNRQGRRGDRRPRRGQRNAAPQQNAAAEAPAAAEAPAATETKE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NUOK_PSEPG
Sequence: MGAIPLEHGLAVAGILFCLGLVGLMVRRNILFVLMSLEVMMNASALAFVVAGARWVQPDGQVMFILVISLAAAEASIGLAILLQLYRRFHTLDIDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMG_SALSV
Sequence: MSHVDDGFRSLTLKRFPQTDDVNPLLAWEAADEYLLQQLDETEIRGPVLILNDTFGALSCALAEHSPYSIGDSYLSELGTRENLRHNGIAESSVTFLDSTADYPQAPGVVLIKVPKTLALLEQQLRALRKVVTAQTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFSHPQLADAPQTLSWKLEDTGWTIHNHANVFSRTGLDIGARFFMQHLPENLDGEIVDLGCGNGVIGLSLLAKNPQANVVFVDESPMAVDSSRLNVETNLPEAFERCEFMINNALSGVEPFRFNAVFCNPPFHQKHALTDNIAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCATIATNNKFVILKAVKQGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FP100_MOUSE
Sequence: MAGASSRVHYLSDFCCPLGGRAAGKPFVLRHEAEVFLSTGREFVYVYDQEGGLLTAVYQFPDQVWHLQLLAIRRALYVLCARTGIYCLSLDSLDRSGSQACEDKEEAAPPYPVIHVDPDACVLPDAALCAFTVLDDMLVTLAQGPTQWKMQLFERPCAGEEPLPRGQIGEVELSTCTPPGGVPEKPAAPRFLPVLCCVFPPDSRAPHGHPQGCGCFTLEEALFGLLFGVDATLLQSPVILCGLPDGQLCCVVLKALVTSGLAPGDPKVLVKILHHLEEPVIFIGALRAEPHEEEAAGELLPGQHEHSDCLVALGHQGRTLAIKASWSESGNLVPELREYCLPGPVLCAACDRDGHVYHSTPSDLCVVDLTRRDSPWNPEKPDGAIGGLPSVLCPASLNICSALALCVTARAPTGSTELLALSSKGRLITCSLDLNSEAPVPAKMAMANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSHPEGDRPIACTITTSWSRLELRDMLMATCTLENSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIPVDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVVGAALAPSDPLEAPYLEQFPLSLPKQEGVCLPLCKRTVDMLQCLRFAGAATHPAQAPCMPGPACEPVETFLKTCQAPGSEPTGAASLRAKYLPPSTASIRVSAGLLRAALEDSHSGFHLCSATLRWLLAENAAVDVVRAQTLSSIQGIAPDGTDVNLTVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRIQTMVTEQAALGSSPPDLRMQYLQQIHANHQELLREVQALRDQLCTEDELSSCSTAQKLLHIYKQLRNPSLVLL
What is the function of this protein?
Plays a role in Fanconi anemia-associated DNA damage response network.  Regulates FANCD2 monoubiquitination and the stability of the FA core complex.  Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed (By similarity).
What are the official names of this protein?
Fanconi anemia core complex-associated protein 100, Fanconi anemia-associated protein of 100 kDa.
What are the subcellular locations of this protein?
Nucleus.
Protein: CS081_HUMAN
Sequence: MQPEVEPVCFPAMGSPTMHRKAGALLMDLETPEEMQARSLGRPIKSSKQYLRQVIAEYEALDRELPCIRKFPTPPASQPLCLCMETLPEEDFTHLEVLQALEAQLPGAMESGRVSSIRFENMNVICGTAGRRNRWLIAVTDFQTRSRLLRSGLSPRGLAHQIVRHDDLLLGDYRLHLRRSLVRRRMLEALGAEPNEEA
What are the official names of this protein?
Putative uncharacterized protein C19orf81.
Protein: HEM3_SYNWW
Sequence: MRNLRLGTRGSQLALWQARHVASLLESSIPDLKVEIKTIKTTGDKILDVALSKIGDKGLFTKEIEKELLDGEIDIAVHSMKDLPSELPPGLCIAAVLEREDPRDVLLSHKNYSLADLPQAALIGTSSLRRIAQLKAWRPDLQLVDMRGNVETRIRKMKEQDLDGIILACAGVKRLGLEEMISDYLPAHLVLPAVGQGMIAVEARSDEQDVLKLLSRINHQDSFLAGQAERGFLHELGGGCQVPVASLAELQGGQLHIRGLIASLDGKEKYSGSSDCSPPEAEEAGRELARSLLQQGGAAILCETRK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ARND_SHIB3
Sequence: MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQKVIEAKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKTEDFNGWLLNRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVVRGNIAGREGWLGCQQIAGSR
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.