PharMolix/UniProtQA huggingface dataset:
Protein: PRX6_PENRW
Sequence: MGSYTEPRVAIVAGATSLTRDPLQSGIGIDLAKDLCSKGWKVACVGRRQEAGEALLKDLPQDRAYFFAADVSNYEQYASVFSKVHHLWGRIDALCANAGIVDTSSLYIYGSKNNGVDNIPPAPDLSVVDINYKGVVYGTQLAIHFMRHNPQPGGRIVVTGSIGAVFPHKTYPVYCGTKAAVNHFIRGVAPLLKQKENISINCVMPGIVNTPIVPPEMIAAVTPECITPVQTVLRGYETFLEDSTGMAGEILECSADKLIYYHMPKPGNGHITKRAVTVWEPLFRMSHGEVSGLPDAIP
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin (PubMed:24239699).  The first step of the pathway is catalyzed by the aristolochene synthase which performs the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene (PubMed:24239699).  Following the formation of aristolochene, the non-oxygenated aristolochene is converted to the trioxygenated intermediate eremofortin B, via 7-epi-neopetasone (PubMed:24239699).  This conversion appears to involve three enzymes, a hydroxysterol oxidase-like enzyme, the quinone-oxidase prx3 that forms the quinone-type-structure in the bicyclic nucleus of aristolochene with the C8-oxo group and the C-3 hydroxyl group, and the P450 monooxygenase prx9 that introduces the epoxide at the double bond between carbons 1 and 2 (PubMed:24239699) (By similarity).  No monoxy or dioxy-intermediates have been reported to be released to the broth, so these three early oxidative reactions may be coupled together (PubMed:24239699).  Eremofortin B is further oxidized by another P450 monooxygenase, that introduces a second epoxide between carbons 7 and 11 prior to acetylation to eremofortin A by the acetyltransferase prx11 (By similarity).  The second epoxidation may be performed by a second P450 monooxygenase (PubMed:24239699).  After the acetylation step, eremofortin A is converted to eremofortin C and then to PR-toxin (PubMed:24239699).  First the conversion of eremofortin A to eremofortin C proceeds by oxidation of the side chain of the molecule at C-12 and is catalyzed by the short-chain oxidoreductase prx1 (PubMed:24239699).  The cytochrome P450 monooxygenase prx8 also plays a role in this step (By similarity).  The primary alcohol formed at C-12 is finally oxidized by the short-chain alcohol dehydrogenase prx4 that forms PR-toxin (PubMed:24239699).
What are the official names of this protein?
Short-chain dehydrogenase/reductase prx6, PR-toxin biosynthesis cluster protein 6.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: KAE1B_NATPD
Sequence: MTRVLGIEGTAWCASAAVFDAETDAVFIDSDAYVPESGGIHPREAAEHMREAVPSVVEAALDHVESNWGDPADAIDAVAFSRGPGLGPCLRIAGTAARSLAGTLSCPLVGVNHMVAHLEIGRHRSGFESPVCLNASGANAHVLGYHNGRYRVLGETMDTGVGNAIDKFTRHVGWSHPGGPKVESHAEDGDYVELPYVVKGMDFSFSGIMSAAKQAYDDGTPVADVCCGLQETIFAMLAEVSERALSLTGADELVVGGGVAQNSRLQEMLTQMCENRGAAIYVPEPRFLRDNAGMIAVLGAKMYEAGDIISIPESGVRPDFRPDEVPVSWRDDEAVARPVPTDERRQGAEAVVDIDADGGRVTKRRLEKAYRHPVLDSRLRSQRTRSEARLTSEARRQGVPTPVVYDVDPDAGRLVFQYVGDADLKTALSESAVRDVGRHLAACHAAGFVHGDPTPRNVRVGEDRAFLIDFGLGYYTDAVEDYAMDLHVFEGALGGTADDPTAQITAFEDAYRSAGDGAVVDHLREIETRGRYQ
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  The Kae1 domain likely plays a direct catalytic role in this reaction.  The Bud32 domain probably displays kinase activity that regulates Kae1 function.
What are the official names of this protein?
Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_FERNB
Sequence: MDFFEINLTAVVQLLNFLFLLWILNKLLYKPFLGMMEKRKEKIEGEIVEAEKLRKQAEEIKKNAEEELKNARIRAEQIIASANSESEKIVEEAKQKAQKEAEKILQNAYLEIEKQKQEALAQVQTIATELAINLAMKVLKGTLDEKAKREYLAKVIKEYEK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MSD3_AMAFL
Sequence: MSDINATRLPVWIGYSPCVGDDAVALLNRGEG
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:24613547).
What are the official names of this protein?
MSDIN-like toxin proprotein 3.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: RGXB_ASPNC
Sequence: MAPIALKILLFTSLIVPSISLSDQARNGHARTICEVKPGGSSEIDDVPAIVDALTTCGSGGRVIFSNNTYHINSVMNTTWLDDVEIDLQGTLLWSTNISYWLNHSLPVGYQNQSTAWILGGKDIVFEGHGYGTFNGSGQTWYRYVGSTSNYPRRPNQLTVSGAMGAVFKGLRFVQSQMWTMSIIHTSNSWFDSIYVNNLYDDGGSAQNTDGANTIYSKNITLTNWEVVNGDDSISTKANSTDITIANCTFTSGLGIAIGSIGQYNGAFETVERLKISNITYEKTTHAVYFKTWTGDQVGYPPNGGGGGLGYASDIVATNLKTNNLKGAPFTISQCTTFSGASGNCTNSKFQIRDLVFTDISGTTDSSDVASFQCSAVAPCEDITIENVSLRIAGNTTHAEEYLCGNVDGTVGFNCTGDVCVGSSATGGC
What is the function of this protein?
Alpha-L-rhamnosidase which is able to degrade p-nitrophenyl-alpha-L-rhamnopyranoside (pnp_Rha).  The natural substrate of this enzyme has not been identified yet.
What are the official names of this protein?
Alpha-L-rhamnosidase rgxB, Exopolygalacturonase B, Exorhamnogalacturonase B, Pnp-rhamnohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DDRGK_ORYSJ
Sequence: MDGGGGMLGAVVCLLLVFAIFPLLLWRRRSDAAHRLPPQPLQDERVLRGGPAPGPAARRMRRRPLSTSADASTSRDRDVDDADSDLEEEIQDVPRGSKKKEKKRQDREAQRQAEEAARDSRRTKQDRYAEMRRKKDEEREAQERLMEEEARARKAKEEEAAALEFEKWKGAFSVDAEGTTESDTQDDGQGLLHNFVEYIKNQKCVPLEDLAAEFRMRTQDCINRIITLEGMDRLSGVMDDRGKFIYISTEEMKAVADYIRKQGRVSISHLASNSNQFIDLEPKPQYNEESNLDENAAAGTEL
What are the official names of this protein?
DDRGK domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDRGK1 family.
Protein: MAP1_STAAW
Sequence: MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: UREG_MYCTA
Sequence: MATHSHPHSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGELSLAVLTNDIYTTEDADFLRTHAVLPDDRIAAVQTGGCPHTAIRDDITANLDAIDELMAAHDALDLILVESGGDNLTATFSSGLVDAQIFVIDVAGGDKVPRKGGPGVTYSDLLVVNKTDLAALVGADLAVMARDADAVRDGRPTVLQSLTEDPAASDVVAWVRSQLAADGV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_STAA8
Sequence: MSEKEIWEKVLEIAQEKLSAVSYSTFLKDTELYTIKDGEAIVLSSIPFNANWLNQQYAEIIQAILFDVVGYEVKPHFITTEELANYSNNETATPKETTKPSTETTEDNHVLGREQFNAHNTFDTFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHHVLDNNPDAKVIYTSSEKFTNEFIKSIRDNEGEAFRERYRNIDVLLIDDIQFIQNKVQTQEEFFYTFNELHQNNKQIVISSDRPPKEIAQLEDRLRSRFEWGLIVDITPPDYETRMAILQKKIEEEKLDIPPEALNYIANQIQSNIRELEGALTRLLAYSQLLGKPITTELTAEALKDIIQAPKSKKITIQDIQKIVGQYYNVRIEDFSAKKRTKSIAYPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKISKDLKEDPIFKQEVENLEKEIRNV
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_XANOM
Sequence: MPELPEVETTLRGLSPHLVGQRIHGVILRRPDLRWPIPEQIERLLPGATITNVRRRAKYLLIDTDAGGSALLHLGMSGSLRVLPGDTLPRAHDHVDISLQNGRVLRFNDPRRFGCLLWQSDIQAHELLAALGPEPLSEAFTGDYLHALAYGRRAPVKTFLMDQAVVVGVGNIYAAESLHCAGISPLREAGKVSLDRYRRLAAAVKDILSYAIRRGGTTLRDFISPDGAPGYFEQELTVYGREGEPCKQCGRVLKHAMIGQRATVWCGSCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: DADA_HELPY
Sequence: MKKEVVVIGGGIVGLSCAYSMHKLGHKVCVIEKNDGANGTSFGNAGLISAFKKAPLSCPGVVLDTLKLMLKNQAPLKFHFGLNLKLYQWILKFVKSANAKSTHRTMALFERYGWLSIDMYHQMLKDGMDFWYKEDGLLMIYTLEESFEKKLKTCDNSGAYKILSAKETKEYMPVVNDNICGSVLLTENAHVDPGEVMHSLQEYLQNVGVEFLYNEEVIDFEFKNNLIEGVITHKEKIQAETIILATGANPTLIKKTKNDFLMMGAKGYSITFKMPEELKPKTSSLFADIFMAMTPRRDTVRITSKLELNTNNALIDKEQIANMKKNLAAFTQPFEMKDAIEWCGFRPLTPNDIPYLGYDKRYKNLIHATGLGWLGITFGPAIGKIIANLSQDGANEKNADIMLFSAFFRD
What is the function of this protein?
Catalyzes the oxidative deamination of D-amino acids.  Has broad substrate specificity; is mostly active on D-proline, and to a lesser extent, on several other D-amino acids such as D-alanine, D-phenylalanine and D-serine.  Mediates electron transport from D-proline to coenzyme Q1 in vitro, and is involved in the electron transport chain from D-proline to the c-type cytochrome in vivo.
What are the official names of this protein?
D-amino acid dehydrogenase, DAD.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TBP_DROME
Sequence: MDQMLSPNFSIPSIGTPLHQMEADQQIVANPVYHPPAVSQPDSLMPAPGSSSVQHQQQQQQSDASGGSGLFGHEPSLPLAHKQMQSYQPSASYQQQQQQQQLQSQAPGGGGSTPQSMMQPQTPQSMMAHMMPMSERSVGGSGAGGGGDALSNIHQTMGPSTPMTPATPGSADPGIVPQLQNIVSTVNLCCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEDDSRLAARKYARIIQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHCNFSSYEPELFPGLIYRMVRPRIVLLIFVSGKVVLTGAKVRQEIYDAFDKIFPILKKFKKQS
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SWET1_DROPS
Sequence: MSAVAYELLSTTAVISTVFQFLSGAMICRKYIQKKSTGDSSGVPFICGFLSCSFWLRYGVLTEEQSIVLVNIIGSTLFLIYTLIYYVFTVNKRAFVRQFAFVLAVLIAVVVVYTNRLADQRDEMIRITGIFCCIVTVCFFAAPLATLLHVIRAKNSESLPLPLIATSFLVSLQWLIYGILISDSFIQIPNFLGCLLSMLQLSLFVVYPPRSYSGQGYKLVEQAVPF
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the membrane.
What are the official names of this protein?
Sugar transporter SWEET1, Protein saliva.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: MNHB1_STAAR
Sequence: MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit B1, Mnh complex subunit B1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSA3_ASHGO
Sequence: MSTEISAAAPRRAANGKKRANRRKKRRTQAESDSSDSSDSSESSQPSADEQEAKTDDVAVELSDVELSDSENKTVSHSEKLDDESKAKLKSIQLTATDLSSKFALQQNRNIDLQKAGREVDHGLEKLAKLDAQTSEQESGRLKTGYINMLFEHVGEDVNQLRNAPDFTPKSLVVLANALKDGGDMFDIESLRALVDNK
What is the function of this protein?
Required for efficient biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome assembly protein 3.
What is the protein family that this protein belongs to?
Belongs to the RSA3 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PANB_SULIL
Sequence: MKKVTIRDFIKKKSTKEKITMLTAYDYPTAKIISNTGLDSILVGDSLGMVVLGYANTLNVTMRDMISHTRAVARANPPQLIVADMPFLSYEIDTKSAIKNAGLLVKAGSDAIKLEGGEEMKDTVKAIVKAGIPVMGHIGLTPQRFLRLGGFRTIGKTKQEEDQLIKDSLELEDAGVFSLVIENTYVDIAKRITEKLNIPTICIGAGPYCDGQVLVINDLLGLSEFTPYFAKSYVNLKEIISNAINQYIIDVKNNKFPEKQHYKERES
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2R43_PANTR
Sequence: MITFLPIIFSSLVVVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVLNPAFNSVEVRTTAYNIWAVINHFSNWLATSLSIFYLLKIANFSNFIFLHLKRRVKSVILVMLLGPLLFLACHLFVINMNEIVRTKEFEGNMTWKIKLKSAMYFSNMTVTMVANLVPFTLTLLSFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKVLQTVISFLLLCAIYFLSIMISVWSFGSLKNKPVFMFCKAMRFSYPSIHPFILIWGNKKLKQTFLSVFWQMRYWVKGEKTSSP
What is the function of this protein?
Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5.  Activated by the sulfonyl amide sweeteners saccharin and acesulfame K.  In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.  May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 43, T2R43.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
Protein: MT_PLEPL
Sequence: MDPCECSKTGTCNCGGSCTCKNCSCTTCNKSCCPCCPSGCPKCASGCVCKGKTCDTSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: ARND_SALCH
Sequence: MTKVGLRIDVDTLRGTREGVPRLLATLHRHGVQASFFFSVGPDNMGRHLWRLIRPRFLWKMLRSNAASLYGWDILLAGTAWPGKNIGNANAGIIRETATYHETGLHAWDHHAWQTHSGHWSIRQLKEDIARGITALEAIIGKPVTCSAAAGWRADGRVVRAKESFNLRYNSDCRGTTLFRPLLMPGQTGTPQIPVTLPTWDEVIGPAVQAQSFNTWIISRMLQDKGTPVYTIHAEVEGIVHQPLFEDLLVRARDAGITFCPLGELLPASPESLPLGQIVRGHIPGREGWLGCQQAASAS
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: PTST3_ARATH
Sequence: MATISQIPFSISFPCFEFRKPSFYYHQPQLFVSYLNSTKKHSFICFACSTKQTRVRKRVKSNEELRSEIMQFVALAGLPEGHVPSMKELSAHGRVDLANIVRRRGYKFIKELVANSGMEEDCNELVADSEDNNTNIETGGSRACLEDSSTDLSKEAEKQGSLSKDESSLAGVLSLENSFSNLGDSNHSGEITEKIFKIESVELNEIADIENSSSEASVFANHSQDLYDTSSCPDIEAGNVSMTEDEEVNDVDKDFSLTFDHYTSPTSNHYTSPDLNSIKHVDIATGSSYDLTSENTMTNVENFQNQQIDDIAANRSGSADDSLVESEDNDWMSGLSSCTSSIEEKTTRFIQNGYLDTVGADENDIPNESCPEESSETTKGGEYIGDSLGGPRIMSTPLNGSALALKEIIHATEVNSSDRNSDQRDGSVGLDTDPHHETRKRENQVEIDRLRFMLDQKELELSRLKEQIEKEKLSLSVLQRQAETEIQKAQMLISEKEVELQEAEESLSGLQEVVIEYCGDGNAVEVTGSFNGWQHRVGMELQASKSIGKQKCWSTLLWLYPGTYEIKFIVDGQWITDPQKDSVTRGHISNNILKVDSQ
What is the function of this protein?
Involved in starch granule initiation in leaf chloroplasts.
What are the official names of this protein?
Protein PTST homolog 3, chloroplastic, PROTEIN TARGETING TO STARCH homolog 3.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ADIPO_BOVIN
Sequence: MLLQGALLLLLALPSHGEDNMEDPPLPKGACAGWMAGIPGHPGHNGTPGRDGRDGTPGEKGEKGDPGLVGPKGDTGETGITGIEGPRGFPGTPGRKGEPGESAYVYRSAFSVGLERQVTVPNVPIRFTKIFYNQQNHYDGTTGKFLCNIPGLYYFSYHITVYLKDVKVSLYKNDKALLFTHDQFQDKNVDQASGSVLLYLEKGDQVWLQVYEGENHNGVYADNVNDSTFTGFLLYHNIVE
What is the function of this protein?
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities.  Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion.  Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects.  Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway.  May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW (By similarity).
What are the official names of this protein?
Adiponectin, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, apM-1.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP9_HELAN
Sequence: MLEGAKSIGAGAATIASAGAAIGIGNVLSSSIHSVARNPSLAKQSFGYAILGFALTEAIASFAPMMAFLISSVIPIKESKKEG
What is the function of this protein?
This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase.
What are the official names of this protein?
ATP synthase subunit 9, mitochondrial, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CEIB_ECOLX
Sequence: MSDPVRITNPGAESLGYDSDGHEIMAVDIYVNPPRVDVFHGTPPAWSSFGNKTIWGGNEWVDDSPTRSDIEKRDKEITAYKNTLSAQQKENENKRTEAGKRLSAAIAAREKDENTLKTLRAGNADAADITRQEFRLLQAELREYGFRTEIAGYDALRLHTESRMLFADADSLRISPREARSLIEQAEKRQKDAQNADKKAADMLAEYERRKGILDTRLSELEKNGGAALAVLDAQQARLLGQQTRNDRAISEARNKLSSVTESLKTARNALTRAEQQLTQQKNTPDGKTIVSPEKFPGRSSTNHSIVVSGDPRFAGTIKITTSAVIDNRANLNYLLTHSGLDYKRNILNDRNPVVTEDVEGDKKIYNAEVAEWDKLRQRLLDARNKITSAESAINSARNNVSARTNEQKHANDALNALLKEKENIRSQLADINQKIAEEKRKRDEINMVKDAIKLTSDFYRTIYDEFGKQASELAKELASVSQGKQIKSVDDALNAFDKFRNNLNKKYNIQDRMAISKALEAINQVHMAENFKLFSKAFGFTGKVIERYDVAVELQKAVKTDNWRPFFVKLESLAAGRAASAVTAWAFSVMLGTPVGILGFAIIMAAVSALVNDKFIEQVNKLIGI
What is the function of this protein?
Colicins are polypeptide toxins produced by and active against E. coli and closely related bacteria.
What are the official names of this protein?
Colicin-Ib.
What is the protein family that this protein belongs to?
Belongs to the channel forming colicin family.
What are the subcellular locations of this protein?
Host membrane.
Protein: HSP34_SCHPO
Sequence: MVLFMKTVQRPEHISLKSCIPFKSLQRQGIVFRLSVRMVMLADDHSISDSALSDSDKNAFKDKNNDFWKAIKNAKNASDINFSDYSIFFAAGGHGTLFDFPSATNLHKGAAKIYSMGGVIAAVCHGPVILPCIKDSTGFSIVKGKTVTAFNEIAEQQMNLMPTFEKYHFKTLNKLFQEAGSNFVDPQEPFDDFVKTDGKLVTGANPASAASTAKAALNSLNS
What is the function of this protein?
Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step.  May play a role in detoxifying endogenously produced glyoxals.  Involved in protection against reactive oxygen species (ROS).
What are the official names of this protein?
Probable glutathione-independent glyoxalase hsp3104, Glyoxalase 3 homolog 4, Heat shock protein 31 homolog 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HSP31-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LANEL_STAEP
Sequence: MNNSLFDLNLNKGVETQKSDLSPQSASVLKTSIKVSKKYCKGVTLTCGCNITGGK
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria such as staphylococci, enterococci and streptococci (By similarity).  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores (By similarity).
What are the official names of this protein?
Lantibiotic epilancin.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.