PharMolix/UniProtQA huggingface dataset:
Protein: COBIJ_MYCTO
Sequence: MSARGTLWGVGLGPGDPELVTVKAARVIGEADVVAYHSAPHGHSIARGIAEPYLRPGQLEEHLVYPVTTEATNHPGGYAGALEDFYADATERIATHLDAGRNVALLAEGDPLFYSSYMHLHTRLTRRFNAVIVPGVTSVSAASAAVATPLVAGDQVLSVLPGTLPVGELTRRLADADAAVVVKLGRSYHNVREALSASGLLGDAFYVERASTAGQRVLPAADVDETSVPYFSLAMLPGGRRRALLTGTVAVVGLGPGDSDWMTPQSRRELAAATDLIGYRGYLDRVEVRDGQRRHPSDNTDEPARARLACSLADQGRAVAVVSSGDPGVFAMATAVLEEAEQWPGVRVRVIPAMTAAQAVASRVGAPLGHDYAVISLSDRLKPWDVIAARLTAAAAADLVLAIYNPASVTRTWQVGAMRELLLAHRDPGIPVVIGRNVSGPVSGPNEDVRVVKLADLNPAEIDMRCLLIVGSSQTRWYSVDSQDRVFTPRRYPEAGRATATKSSRHSD
What is the function of this protein?
Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
What are the official names of this protein?
Cobalamin biosynthesis protein CobIJ.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: LEUD_AROAE
Sequence: MKPFTELNGRVAPLDRANVDTDAIIPKQFLKSIKRSGFGPNLFDEWRYTDHGEPGQDCVNRPKNPDFVLNQPRYEGAQILLTRDNFGCGSSREHAPWALEDYGFRVLIGSSFADIFFNNCFKNGLLPIVLPAPEIDELFRQCEATDGYRLKVDLATQTIVRPDGKTIAFEVDPFRKECLLNGWDDIGLTLRHADRIRTFEEKRRADHPYYFVA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: COMT3_POPKI
Sequence: MGSTGETQMSPAQILDEEANFAMQLISSSVLPMVLKTAIELDLLEIMAKAGPGALLSPSDIASHLPTKNPDAPVMLDRILRLLASYSILICSLRDLPDGKVERLYGLASVCKFLTKNEDGVSVSPLCLMNQDKVLMESWYHLKDAILEGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSKMAMKKILESYKGFEGLASLVDVGGGTGAVVSTIVSKYPSIKGINFDLPHVIADAPAFPGVENVGGDMFVSVPKADAVFMKWICHDWSDEHCLRLLKNCYDALPENGKVILVECILPVAPDTSLATKGVMHVDAIMLAHNPGGKERTDKEFEGLARGAGFKGFEVMCCAFNTHVIEFRKQA
What is the function of this protein?
Catalyzes the conversion of caffeic acid to ferulic acid and of 5-hydroxyferulic acid to sinapic acid.  The resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins.
What are the official names of this protein?
Caffeic acid 3-O-methyltransferase 3, CAOMT-3, COMT-3, S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: NREC_STAEQ
Sequence: MKIVIADDHAVVRTGFSMILNYQEDMEVVATAADGVEAYQKVLEHRPDVLILDLSMPPGESGLIATSKISESFPDTKILILTMFDDEEYLFHVLKSGAKGYILKNSPDEQLILAVRTVYQGETYVDMKLTTSLVNEFVNQSQTDEVSSSSDPFKILSKRELEILPLIAKGYGNKDIAEKLFVSVKTVEAHKTHIMTKLNLKSKPELVEYALKKKLLEF
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity).
What are the official names of this protein?
Oxygen regulatory protein NreC, Nitrogen regulation protein C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENPP5_MOUSE
Sequence: MIPEFLLASCTLATLCHSAPFSLQPEEQKVLVVSFDGFRWDYLYKVPTPHFHYIMKNGVHVNQVTNVFITKTYPNHYTLVTGLFAENHGIVANDMFDPILNKSFSLEHMDIYDSKFWEEATPIWITNQRAGHASGAAMWPGADVKIHDSFPTYYLPYNESVSFEDRVAKIIEWFTAKDPINLGFLYWEEPDDTGHDVGPDSPLMGSVISDVDHKLGYLIKMLKRAKLWNNVNLIVTSDHGMTQCSKQRVIELDRYLDKEHYTLIDHSPVAAILPKEGKFDEVYDALAGAHPNLTVYKKEEIPERWHYKHNDRVQPIVAVADEGWYILQNKSDDFLLGNHGYDNALAEMHPIFLAHGPAFRKNFTKEAMNSTDLYSLLCHLLNLTALPHNGSFWNVQDLLSSATPKPIPYTQSTTLLLGSDKPGEDEQEESYPYYIGVSLGSIIAMVFFVVLIKHLIRSQVHTLQYRQVEVAQPLLQA
What is the function of this protein?
Can hydrolyze NAD but cannot hydrolyze nucleotide di- and triphosphates (PubMed:28898552).  Lacks lysopholipase D activity.  May play a role in neuronal cell communication (By similarity).
What are the official names of this protein?
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5, E-NPP 5, NPP-5.
What is the protein family that this protein belongs to?
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
What are the subcellular locations of this protein?
Secreted. Membrane; Single-pass membrane protein.
Protein: Y350_HAEIN
Sequence: MSNSLSSQIFTRKMLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYIISLFDPLTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWETVFLWTALCMLAGIFMTLFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKFGDSFATTLQTKFIYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHFDVITSAELWKLGVVIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGMLCLFWVAPLKQENNKTSSV
What are the official names of this protein?
Uncharacterized protein HI_0350, ORF3.
What is the protein family that this protein belongs to?
To E.coli AmpG and yeast YBR220c.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_METNO
Sequence: MGKAAAPRALPENEAKAVARMLRVSPQKLNLVAQLIRGKKVATALADLQFSQKRIAVEVKKCLESAIANAENNHDLDVDDLVVKEAYVGKALVLKRFHARARGRGARILKPFSNLTIVVREVRAEAA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GREA_CLOD6
Sequence: MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGDLSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFDEEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RS10_PYRHO
Sequence: MQKARIKLASTNVRSLEEVANQIRQIAERTGVRMSGPIPLPTKRIRIVTRKSPDGEGSATFDRWELRIHKRLIDIEADERAMRQIMRIRVPEDVTIEIELIS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ATG5_PICAN
Sequence: MSTSEIISRVWGGVLYMQFHLDRALSNQECPSFYVAVHRNSYLHNSLPAILQFFKPFLKDARLAQSQKWWFEFEKVPLKWNFPVGLLYDLVTTDAQVEKQMWEITLKYYDYPIEYVIPIDQNPSFLKDHWTNQLKEACFILNGSSKLVMNMSRTDSDDFYHAAIHKDSTQFESMFRKLLPSSVSSLKNLPIKVYLPLSNKLIQPVLSNLGRKITLGNLLQDLIPDLFPSSLMYTVAHPYSHGVVLPLDSSIIDLYICMKSLDGFLHISIKMIQKNEH
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production.  Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: RFBF_BACSU
Sequence: MKAVILCGGKGTRMSEVTNDIPKPLAMIGGKPILWHIMKIYQYYGVNEFILLLGYKGEKIKEYFLDYEWKHNSLTLDSSTGEVQMLGQPETWKITFLETGVDTLTAGRILQAKDYIGDETFLLTYGDGLANINLFHLISYHQTKGAAATVTGIDKVSQFGTLTVEDGMAKTFSEKTSSDGIINGGFFVLSPKVFDYLPKDGNTMFEDEPLKNLAKDGELAVYRHYGFWTAIDTYKNLLEVNKMWNQGQQVWKVW
What is the function of this protein?
Catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate.
What are the official names of this protein?
Probable glucose-1-phosphate cytidylyltransferase, CDP-glucose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the glucose-1-phosphate cytidylyltransferase family.
Protein: CC50A_MOUSE
Sequence: MAMNYSAKDEVDGGPAGPPGGAAKTRRPDNTAFKQQRLPAWQPILTAGTVLPTFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTEPSSPCNKCLSPNVTSCACTINFTLKQSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDPSALLNPSKECEPYRRNEDRPIAPCGAIANSMFNDTLELYLVANESDPKPIPIPLKKKGIAWWTDKNVKFRNPPGKESLEEKFKDTIKPVNWHKAVYELDPEDESNNGFINEDFIVWMRTAALPTFRKLYRLIERRDDLHPTLPAGQYFLNITYNYPVHSFDGRKRMILSTISWMGGKNPFLGIAYITIGSISFLLGVVLLVINHKYRNSSNTADITI
What is the function of this protein?
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids.  Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules.  The beta subunit may assist in binding of the phospholipid substrate.  Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex.  ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE).  The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane.  Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes.  Involved in uptake of platelet-activating factor (PAF).  Can also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations.
What are the official names of this protein?
Cell cycle control protein 50A, P4-ATPase flippase complex beta subunit TMEM30A, Transmembrane protein 30A.
What is the protein family that this protein belongs to?
Belongs to the CDC50/LEM3 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell membrane. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle membrane. Apical cell membrane.
Protein: Y510_BACC0
Sequence: MGFPKEGEKVQIHSYKHNGSIHRMWEETTILKGTQSLVIGANDRTVVTESDGRTWITREPAICYFHANYWFNVIGMLREEGVYYYCNLSSPFAYDSEALKYIDYDLDIKVYPDMTYTLLDEDEYEKHSQIMQYPPVIDTILKRNVAQLTQWIHQRKGPFAPDFVDMWYERYLMYRN
What are the official names of this protein?
UPF0374 protein BCAH820_0510.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: CCS1_ARATH
Sequence: MIVTLNPKILHFSKIHPFSRPSSYLCRTRNVSLITNCKLQKPQDGNQRSSSNRNLTKTISLSDSAPPVTEETGDGIVKGGGNGGGGGGDGRGGLGFLKILPRKVLSVLSNLPLAITEMFTIAALMALGTVIEQGETPDFYFQKYPEDNPVLGFFTWRWISTLGLDHMYSAPIFLGMLVLLAASLMACTYTTQIPLVKVARRWSFMKSDEAIKKQEFADTLPRASIQDLGMILMGDGFEVFMKGPSLYAFKGLAGRFAPIGVHIAMLLIMVGGTLSATGSFRGSVTVPQGLNFVMGDVLAPIGFFSIPTDAFNTEVHVNRFTMDYYDSGEVSQFHSDLSLRDLNGKEVLRKTISVNDPLRYGGVTVYQTDWSFSALQVTKDGEGPFNLAMAPIKINGDKKLYGTFLPVGDTNAPNVKGISMLARDLQSIVVYDLDGKFAGIRRPSSKLPIEINGMKIVIEDAIGSTGLELKTDPGVPVVYAGFGALMLTTCISYLSHSQIWALQNGTALVVGGKTNRAKNQFPDDMNRLLDQVPELIKKNTSVVSEQS
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CCS1, chloroplastic, C-type cytochrome synthesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: INVA2_PAXIN
Sequence: MTPIAVTPVAPVDIIYDLKHTERATESSPVTLLDVFSRAVSQYPNHELSFITSSAHDSTIHTKTFAEFNQDVHALAQAMRAWGKPTGSVIVVYLTEHEDNMAAVWASLLAGYVPCLQPALSAQQAHKEGHVGHIKNLFSSATWLTNESGAEQVQSISGLDIHLLSELKASAEAGVDFQAHQPNSDDEAILFLTSGSTGFSKAVVHTHRTILAACHAKGESYGLTSESKIMNWVGFDHVAGSLEMHIAPLLYGASQLHVHASAILSDPLRFLHLIEEKSIQLAFAPNFLLAKLTRDLEKRSDLFGKFDLSSIKRINSGGEAVVSSTAQAFARTLKNLAKDGDASFVISAGFGMTETCAGCIYDPINVLETPPSYEFLELGTPVAGCEMRVVNPEDGVTPRPDGESGELQVRGPMVFVRYYNNPEATSSSFVEGGWYRTGDVGIVEQGKMRLSGRIKDTVIVHGVSYGIPELETYLQTVEGVTHSFLAAAPYRAPGQETEGFVVFYSPTFDLDSEDAPAKLFATHRALRDVSVKLITLPPQQIIPIPINQMEKTTLGKLSRARLVNLFKQGELAKHIDRAEELVSIARGASFVAPSTETEKTLAGIYAGIFNLSVGDMSASENFFELGGTSIDVIRLKREGESAFDLPEIPTIQILKHPVISSLAKYVDSLISKDASQEEYDPIVPLQLTGNKTPIFMVHPGVGEVLIFVNLAKYFQNERPFYALRARGFEPGHPFFTTMDEMVSSYAAAIKRTQAHGPYAIAGYSYGGVVAFEVAKRLEAMGDEVKFTGLINIPPHIADRMHEIDWTGGMLNLSYFLGLVSKQDANDLAPSMRPLTRKEQLEIVWKLSPPERLVELQLTPEKLDHWVDIAGSLIECGKTYEPASSVSVLDVFYAIPLRGSKEDWLNNQLKPWAGYSRAEPSYTDVPGQHYTLMDFDHVPGFQKIFRSRLEARGL
What is the function of this protein?
An L-tyrosine:2-oxoglutarate aminotransferase (probably invD) and atromentin synthetase invA2 catalyze consecutive steps to turn over L-tyrosine into atromentin, which represents the generic precursor molecule for the entire terphenylquinone and pulvinic acid family of pigments, which are widely distributed secondary metabolites in homobasidiomycetes.  The first step catalyzed by the aminotransferase converts L-tyrosine in to 4-hydroxyphenylpyruvate (4-HPP).  Adenylation of two 4-HPP monomers by the invA2 adenylation (A) domain, covalent tethering of the monomers as a thioester and oxoester onto the invA2 thiolation (T) and thioesterase (TE) domains, respectively, and symmetric C-C-bond formation between two monomers catalyzed by the invA2 TE domain leads to atromentin.
What are the official names of this protein?
Atromentin synthetase invA2, Nonribosomal peptide synthase-like enzyme invA2, NRPS-like.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: SYE1_RICRO
Sequence: MTKVITRFAPSPTGMLHVGNIRAALLNWLYAKKHNGQFILRFDDTDLERSKQEYKDAIEEDLKFLNINWDQTFNQLSRLSRYDAIKNLLLDKKRLYACYETPEELELKRKFQLSKGLPPIYDRASLNLTEEQAKKYIEQGRKPHYRFLVNHEPISWHDMIKGEVKYDGKALSDPIVIRADGSMTYMLCSVIDDIDYDITHIIRGEDHVSNTAIQMQMFEALNTTPPTFGHLSLIINKDEKISKRVGGFEIATLRKEIGIEAMAIASFFSLLGSSAQILPYKSMEKLANQFEISSFSKSPTIYQPEDLERLNHKLLISLDFDTVKERLKEIDAEYIDENFWLSVSPNLQKLRDVKDWWEICHQTPNVENLNLDKEYLKQAAELLPKGEITKDSWSIWTKEITNITGRKGKELFLPLRLALTARESGPEIASVLPLIDREEIIKRLTSA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUB_BACLI
Sequence: MSYRVKRMLMLLVTGLFLSLSTFAASASAQTGGSFYEPFNNYNTGLWQKADGYSNGNMFNCTWRANNVSMTSLGEMRLSLTSPSYNKFDCGENRSVQTYGYGLYEVNMKPAKNVGIVSSFFTYTGPTDGTPWDEIDIEFLGKDTTKVQFNYYTNGVGNHEKIVNLGFDAANSYHTYAFDWQPNSIKWYVDGQLKHTATTQIPQTPGKIMMNLWNGAGVDEWLGSYNGVTPLSRSLHWVRYTKR
What are the official names of this protein?
Beta-glucanase, 1,3-1,4-beta-D-glucan 4-glucanohydrolase, Endo-beta-1,3-1,4 glucanase, Lichenase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
Protein: RPB5_ASFWA
Sequence: MAMQKLFTYIYEFIEYRKMVLLEEKVPYDKFVQMVLNTGFFRINAETLNHGIVSVFIFGANGKYVHHGGDMRTLLTNTLNEKKHYEELILIVDKPVLSKKNILDIIVEQRAANPTIVINIYPYHLFCINIPKVSAIPKHKLITQEEAQEFLGREYLQPQDLMQISASDPPVVWLGGRPGDFVQIERPSETAMHAVVIRFITKSKI
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase RPB5 homolog, RPB5 homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: NDBV_LYCMC
Sequence: MVSTLMIASVKLRLYCTALIILCNQKNPSEFNVLIHKLIIKWGFMNKNFHFVSVFFIKF
What are the official names of this protein?
Venom protein 37.1.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL23_IDILO
Sequence: MMREERLLKVILAPHVSEKSTNTAENNNTVVFKVAVDATKTEIKAAVEKLFEVEVKNVRTVNVKGKTKRTGSRFGKRSDWKKAYVALNEGADIDFSGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y415_HELPJ
Sequence: MRLLLWWVLVLSLFLDPLRAVEEHETDAVDLFLIFNQINQLNQVIETYKKNPERSAEISLYNTQKNDLIKSLTSKVLNERDKIGIDINQNLKEQEKIKKRLSKSIKGDDFYTFMKDRLSLDILLIDETLYRFIDKIRSSIDIFSEQKDVESISDAFLLRLGQFKLYTFPKNLGNVKMHELEQMFSDYELRLNTYTEVLRYIKNHPKEVLPKNLIMEVNMDFVLNKISKVLPFTAHSLQVSKIALALMILALLLGLRKLITWLLALLLDRIFEIMQRNKKMHVNVQSSIVSPVSVFLALFSCDVALDIFYYPNASPPKVSMWVGAVYIMLLAWLVIALFKGYGEALVTNVATKSTHNFRKEVINLILKVVYFLIFIVALLGVLKQLGFNVSAIIASLGIGGLAVALAVKDVLANFFASVILLLDNSFSQGDWIVCGEVEGTVVEMGLRRTTIRAFDNALLSVPNSELAGKPIRNWSRRKVGRRIKMEIGLTYSSSQSALQLCVKDIKEMLENHPKIANGADSALQNASDYRYMFKKDIVSIDDFLGYKNNLFVFLDQFADSSINILVYCFSKTVVWEEWLEVKEDVMLKIMGIVEKHHLSFAFPSQSLYVESLPEVSLKEGAKI
What are the official names of this protein?
Uncharacterized MscS family protein jhp_0969.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FX1AB_DANRE
Sequence: MAEPQQQLVDIDPDFEPLSRPRSCTWPLHRPEFSEQPGNSNTSSPAPSVKPEQGIVDFINSLSLLEETEDYPDEKPVLLNDFHCQDNCAHPQQQHPQQPNPQLTHPQQVPPLPAPASGSSPAAAQRKSSSSRRNAWGNMSYADLITKAIESSPEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFVRVQNEGTGKSSWWMLNPEGGKSGKSPRRRATSMDNNSKFTKSRGRAAKKKMSLQGGLDGGSNSPGSQYPKWLGSPNSHSNDDFEPWGNFRTRASSDASTLSGRRSPFLPEEDEAAEVHIGYPGTKLGGPLPSLSEVAGHHGSENMMDNLLENLNLISPKNNTQGSQEAQTALSSPLMQGSPGYPSYTSPNMGPQPQVQQDYRKCLYGQGGVGGLNPISIPTLSDSKPGGYGPFVGQYNCAPGLLKELLTADADPRGELMQSGEGQPVLPSYASQGQMAQGGKMITHPHLHAHPRSLHQLPSPAMGLNGCAMLPHGHPVRLSSMKPQPHLPHHTHLGRGGGEAGMPSYTNGNGFHRHGAIAHHHHSHPERLPSDLDDMLIDQLDVECDVERVLHDTLMDGDALDFNFDPMSSQQSFTHSVKTSTHNWVSG
What is the function of this protein?
Transcription factor that regulates metabolic homeostasis in response to oxidative stress (By similarity).  Binds to the consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3' (By similarity).  Main regulator of redox balance and osteoblast numbers and controls bone mass.  Orchestrates the endocrine function of the skeleton in regulating glucose metabolism (By similarity).
What are the official names of this protein?
Forkhead box protein O1-B.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and nucleus.
Protein: YOSK_BACSU
Sequence: MSQSNYRPSVPRWVGDILELDKKRRQNQYRGSLTSGQEKKDWDEWKRRYSRKLKYARLNGWTIEEE
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YosK.
Protein: RSKA_MYCTU
Sequence: MTEHTDFELLELATPYALNAVSDDERADIDRRVAAAPSPVAAAFNDEVRAVRETMAVVSAATTAEPPAHLRTAILDATKPEVRRQSRWRTAAFASAAAIAVGLGAFGLGVLTRPSPPPTVAEQVLTAPDVRTVSRPLGAGTATVVFSRDRNTGLLVMNNVAPPSRGTVYQMWLLGGAKGPRSAGTMGTAAVTPSTTATLTDLGASTALAFTVEPGTGSPQPTGTILAELPLG
What is the function of this protein?
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK.  ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP).  RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses.  The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor.
What are the official names of this protein?
Anti-sigma-K factor RskA, Regulator of SigK, Sigma-K anti-sigma factor RskA.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-K factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PUTA_SALTY
Sequence: MGTTTMGVKLDDATRERIKMAASRIDRTPHWLIKQAIFSYLDKLENSDTLPELPALFVGAANESEEPVAPQDEPHQPFLEFAEQILPQSVSRAAITAAWRRPETDAVSMLMEQARLSPPVAEQAHKLAYQLAEKLRNQKSASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGRLVSTHNEANLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAQALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGLNIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLVDLASRSRRRLMIRLVKGAYWDSEIKRAQMEGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADATLPLDELVADPVEAVEKLAQQEGQAGIPHPKIPLPRDLYGEGRINSAGLDLANEHRLASLSSALLSNAMQKWQAKPVLEQPVADGEMTPVINPAEPKDIVGWGREATESEVEQALQNAVNQAPVWFATPPQERAAILQRAAVLMEDQMQQLIGLLVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFDNETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTSLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTADARVRGVMFTGSTEVATLLQRNIATRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDDIAEHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRAKGRPVFQAARENSDDAQEWQTGTFVMPTLIELENFAELEKEVFGPVLHVVRYNRNQLAELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLAHRPPNALNTTLTRQDARYPVDAQLKTTLLAPLTALTQWAADRPALQTLCRQFADLAQAGTQRLLPGPTGERNTWTLLPRERVLCLADDEQDALTQLAAVLAVGSQALWSDDAFHRDLAKRLPAAVAARVQFAKAETLMAQPFDAVIFHGDSDKLRTVCEAVAAREGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
What is the function of this protein?
Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon.
What are the official names of this protein?
Bifunctional protein PutA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the aldehyde dehydrogenase family.
Protein: ASTE_BURP1
Sequence: MTSSADSGRDAAWLDDFLALTLAGDAPPAEAGECAARAVRWRWLGDGLLRLEPADAAQRMQSVLVSAGVHGDETAPIELLSTLVRDIARGALPLRCRLLVALGNPGAMRAGERYLDDDLNRLFGGRHAQLAASREAPRAAQLEAAAALFFSTAGRARGARWHIDMHTAIRASVFEQFALLPHTGEPPTRTMFEWLGEAQIAAVLLHTTKGSTFSHFTAQACGALACTLELGKVMPFGANDLSRFAPADAAVRRLVSGRRDAPRGALPRAFTVVDQITKQSDALELFVANDVPNFTPFARGTLLARDGDYRYAVRHEQERIVFPNPSVKPGLRAGLLVIETTRDTHAALA
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.