PharMolix/UniProtQA huggingface dataset:
Protein: RS5_STAA2
Sequence: MARREEETKEFEERVVTINRVAKVVKGGRRFRFTALVVVGDKNGRVGFGTGKAQEVPEAIKKAVEAAKKDLVVVPRVEGTTPHTITGRYGSGSVFMKPAAPGTGVIAGGPVRAVLELAGITDILSKSLGSNTPINMVRATIDGLQNLKNAEDVAKLRGKTVEELYN
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SERC_STRMU
Sequence: MTIYNFSAGPAVLPKPVLEKAQTEFLDYNHSGMSVMELSHRSKDFDDIIKDAEKLLRDLMAIPDNYRVMFLQGGASLQFSMLPLNLAQGRKAYYVVAGSWGKKAYAEAVKLSKTIPFEPILLASSEETTYDHIPEIDSAKIDKDAAYVHITTNNTIEGTSIYDLPETHGVPIVADMSSNILAVRYNVADFGLIYAGAQKNIGPAGVTIVIVREDLLNDEPVLSSMLDYRIQAEAGSLYNTPPTYGIYIAKLVFEWLKELGGVDEMEKINREKSGLLYDFIEQSDFYTSPVKSPKDRSVANIPFVTPSQDLDAKFVKEADALGFKNIKGHRSVGGMRASLYNAFPRQGVLDLIDFMKKFEAENK
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_XANC5
Sequence: MALERTLSIIKPDAVAKNVIGEIYSRFEKAGLKVVAAKYKQLSRREAEGFYAVHRERPFFNALVEFMISGPVMIQALEGENAVAAHRDLLGATNPKDAAPGTIRADFADSIDANAAHGSDSVENAANEVAYFFAATEVVSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_ALBFT
Sequence: MTEFLTAAFYKFVELPDFAQLKAPLLTCCEANDVKGTILLATEGINSTIAGPAVGVHAVLAYLRRDPRLADLQHKEAWSAKAPFYRMKVRLKREIVTMGVPGIDPNLVVGTYVKPQDWNALIGDPDVVVIDTRNDYEVGIGTFAGAVNPDIQSFAMLPQWLAQAPALHPATGKKPKVAMFCTGGIRCEKSTALLRAQGFDEVFHLEGGILKYLETIPPEQSLWQGQCFVFDERVSVGHGLIPGQHDLCRACRQPLDDADLASPLFEAGVSCPKCHAITRDIQKDGARERQRQWELAKARQQVHIGASPEPKAMPATAGR
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RUSD3_BOVIN
Sequence: MGGWRVLGQASGGWRRGLGIRATSTAAGFGTKARHQLQRRGASKPSDPPGDQPFPGLLRPGTFSREELVDVLRAAVVDSKGPLVTLNKPQGLPVTGKPGELTLLSVLPELSRSLGLGEQEVQVVRASGKEASGLVLLSSCSQTASRLQKFFTHSRRARKPTATYCAVTDGIPVTSEGKIQAALKLEHIDGVNLVVPVQSPSRKDIMEGVKRTLSHFRVVATGSGCALVQLQPLTVFPSQLQAHMALQLCPVLGDHTYSARVGTVLGQRFLLPVESTKPQRQVLDEALLGRLCLTASQAARLPLHLHLHCLRLPGARPRDPPIELLAPLPSYFSRTLQCLGLHYQ
What is the function of this protein?
Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs), a post-transcriptional modification necessary for their translation.  Acts at position 390 in COXI mt-mRNA and at position 697-699 in mitochondrial COXIII mt-mRNA.  As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and may play a role in mitochondrial ribosome biogenesis.
What are the official names of this protein?
Mitochondrial mRNA pseudouridine synthase RPUSD3, RNA pseudouridylate synthase domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Note=Localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly.
Protein: VPS10_YEAST
Sequence: MILLHFVYSLWALLLIPLTNAEEFTPKVTKTIAQDSFDILSFDDSNTLIRKQDTSVTISFDDGETWEKVEGIEGEITWIYIDPFNRHDRAVATAMNGSYLYITNDQGKSWERITLPDSGESISPRECYIETHPLNKNYFLAKCNYCEKTEVNNDNEENSGDEEGQFEIFNITRCTDKVFASNDGGKSFSEIKSSLERNENSPISISDCGFAKTSKDSDLESSDTSIICLFQNMQLIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNGYRILKSHMVVLTQGDRYNDMSSMDVWVSNDLSNFKMAYMPTQLRHSMQGEIYEDAMGRIILPMSRERSDQEEDKGIVSEILISDSQGLKFSPIPWTANEVFGYINFYQPTYLKGTMIASLYPLSRRRNRKGKAKGVKSKGVTKISVDNGLTWTMLKVVDPDNADSFDCDITDFENCSLQNMFYTREGSTPTAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAVGDYGNVIVAIPYNADEDDDPQSEFYYSLDQGKTWTEYQLETTIYPNEVMNTTPDGSGAKFILNGFTLAHMDGTTNFIYAIDFSTAFNDKTCEENDFEDWNLAEGKCVNGVKYKIRRRKQDAQCLVKKVFEDLQLFETACDKCTEADYECAFEFVRDATGKCVPDYNLIVLSDVCDKTKKKTVPVKPLQLVKGDKCKKPMTVKSVDISCEGVPKKGTNDKEIVVTENKFDFKIQFYQYFDTVTDESLLMINSRGEAYISHDGGQTIKRFDSNGETIIEVVFNPYYNSSAYLFGSKGSIFSTHDRGYSFMTAKLPEARQLGMPLDFNAKAQDTFIYYGGKNCESILSPECHAVAYLTNDGGETFTEMLDNAIHCEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSSTDFFQDDKNTVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVGKQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKIQGLEGIILTNIVSNSDKVAENKEDKQLKTKITFNEGSDWNFLKPPKRDSEGKKFSCSSKSLDECSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGPNLLPYKECSTFFTTDGGETWAEVKKTPHQWEYGDHGGILVLVPENSETDSISYSTDFGKTWKDYKFCADKVLVKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKYSPLGSKSNCLFGHQTEFLRKTDENCFIGNIPLSEFSRNIKNCSCTRQDFECDYNFYKANDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYRKIPLSTCEGGLKLDAPSSPHACPGKEKEFKEKYSVSAGPFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIRLGDDGLIENNNTDRVVNNIVKSGFYVFSNIGSLLQHTKTNIAHAISKIRGRFGNRTGPSYSSLIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEEHTSYTDQPTTTDVPDTLPEGNEENIDRPDSTAPSNENQ
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  May execute multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment.  Binds the Golgi-modified P2 form of CPY, and this interaction is dependent on the presence of an intact CPY vacuolar protein sorting signal.
What are the official names of this protein?
Vacuolar protein sorting/targeting protein VPS10, Carboxypeptidase Y receptor, CPY receptor, Carboxypeptidase Y-deficient protein 1, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10, Vacuolar protein sorting-associated protein 10, Vacuolar protein-targeting protein 1.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartments.
Protein: IF2_RICRS
Sequence: MTDNQEIKPKKLTLGNSKLSLNKSFDSLTGAQSFVNAKSKTLVEVRKSSTGSATTLSLNKERNSLDQTVIDANKEEFNRRLSILKKAAEQSQLNDPSKISTLSKLASINQSANSKIEPLETDKEVEQKQQNTEDNKVEVSAKIVQDDKDIPSQIPKKKEETFVKSPLVGMRTRYGIESEKELDKTADSKIIAPKIKLEEPKKIKKADLFNMLSDDESGSCRTRSLASIKRAREKEKRKLASQAPEKVYREVTIPEVIGVGDLANAMSERVADVIKELMKLGILANASQTIDADTAELVATNLGHTVKRVQESDVENVLISDDKVEDLRTRAPVVTVMGHVDHGKTSLLDALKSTDVAAGELGGITQHIGAYRVTLADGRAITFIDTPGHEAFSEMRSRGAKVTDIVIIVVAADDGIKTQTVEAINHAKAAGVPIIVAINKIDKPDIDIERVKNELYVHEIIGEEVGGDVMIIPISALKKINLDKLEEAILLIAEMQDLKANPFGSAAGVVIESKIEQGRGTLTTILVQRGTLRNSDIIIAGTAYGKVKKMTNDKGLEIVEATPSVPVEIQGLNEVPFAGDKFNIVQNEKQAKDIAEYRMRLAKEKKISIAPRSSLEDLFLKASGNSKIKELPLIIKGDVQGSVEAISGSLLKLPSDEIKLRILHSGVGPITESDVSLAHASSAIIVSFNVRAGANALTAAEKEKVDIRYYSIIYHLIDDIKAIMSGMLEPIVREQYIGSAEIRQIFNITKVGKIAGSYVTKGIIKKGAGVRLLRDNVVIHEGKLKTLKRFKDEVKEVREGYECGIAFENYEDIREGDTVEVFELIQEQRQL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_ECOLC
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: NAGK_ECO27
Sequence: MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVCELVAEADRRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFTQYSLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRLPVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIAFYDQGDEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLAERLPRHLLPVARVPRIERARHGDAGGMRGAAFLHLTD
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: DEGP9_ARATH
Sequence: MKNSEKRGRKHKRQDASSAENAGGEVKEASANEASLPQSPEPVSASEANPSPSRRSRGRGKKRRLNNESEAGNQRTSSPERSRSRLHHSDTKNGDCSNGMIVSTTTESIPAAPSWETVVKVVPSMDAVVKVFCVHTEPNFSLPWQRKRQYSSGSSGFIIGGRRVLTNAHSVEHHTQVKLKKRGSDTKYLATVLAIGTECDIALLTVTDDEFWEGVSPVEFGDLPALQDAVTVVGYPIGGDTISVTSGVVSRMEILSYVHGSTELLGLQIDAAINSGNSGGPAFNDKGKCVGIAFQSLKHEDAENIGYVIPTPVIVHFIQDYEKHDKYTGFPVLGIEWQKMENPDLRKSMGMESHQKGVRIRRIEPTAPESQVLKPSDIILSFDGVNIANDGTVPFRHGERIGFSYLISQKYTGDSALVKVLRNKEILEFNIKLAIHKRLIPAHISGKPPSYFIVAGFVFTTVSVPYLRSEYGKEYEFDAPVKLLEKHLHAMAQSVDEQLVVVSQVLVSDINIGYEEIVNTQVVAFNGKPVKNLKGLAGMVENCEDEYMKFNLDYDQIVVLDTKTAKEATLDILTTHCIPSAMSDDLKTEERN
What is the function of this protein?
Serine protease that degrades the two-component response regulator ARR4 (PubMed:27274065, PubMed:29180814).  Regulates ARR4 stability by targeting ARR4 in the nucleus for degradation.  Acts upstream of ARR4 and regulates the activity of ARR4 in cytokinin and light-signaling pathways.  ARR4 mediates the cross-talk between light and cytokinin signaling through modulation of the activity of phytochrome B (PubMed:27274065).
What are the official names of this protein?
Protease Do-like 9.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_BDEBA
Sequence: MNLILFGAPGAGKGTQSELLIKRQGMTQISTGDLFRAAIKGQTDLGKKAQEFMDKGQLVPDSIVIGMVEEVLQKGVQNFILDGFPRTVAQAQALDELLVKMNLSIGKAIFLEVPMRILMDRLTGRRVCKNCGAVYHIVSKPSKVEGKCDLCGGEVIQRNDDKAEVIETRLKTYEEFTSPLKEFYKKSGKYTEVDGNRDTEEVYKEIEKIIK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4C_CRUWA
Sequence: MNDFPWLTIIVVFPISAGSLMLFLPHRGNKVNKWYTISICILELLLTTYAFCYNFKMDDPLIQLSEDYKWINFCDFYWRMGIDGLSIGTILLTGFITTLATLAAFPVTRDSRLFHFLMLAMYSGQIGSFSSRDLLLFFIMWELELIPVYHLLSMWGGKKRLYSATKFILYTAGSSIFLLIGVLGISLYGSNEPTLNLELLANQSYPVTLEILFYIGFLIAFAVKSPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLPHAHSMFSPWLMVVGTIQIIYAASTSPGQRNLKKRIAYSSVSHMGFIIIGISSITDPGLNGAILQIISHGFIGAALFFLAGTSYDRIRLVYLDEMGGMAISIPKIFTMFTILSMASLALPGMSGFVAELIVFFGIITSQKYFVISKIFIIFVMAIGMILTPIYLLSMSRQMFYGYKLINVKNFSFFDSGPRELFLSISILLPIIGIGIYPDFVLSLASDKVESILSNYFYG
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYK_CHLTA
Sequence: MSVEVEYLQHEDYLYRTSKLKEIRDLGINPYPYQYTDCLEVQEIRNQFVDNELGDSEAAFRKETPKVRFAGRLVLFRSMGKNSFGQILDNDAKIQVMFNRDFSAVAGLAADAGISPIKFIEKKLDLGDILGLEGYLFFTHSGELTVLVETVTLLCKSLISLPDKHAGLADKEIRYRKRWADLISSEDVRKTFLTRSRILKLIREYMDQQSFLEVETPILQTIYGGAEATPFVTTLQALHAEMFLRISLEIALKKLLVGGMSRVYEIGKVFRNEGIDRTHNPEFTMIEAYAAYWDYNDVMKCVENLVEYIVRALNNGETQVQYSHLKSGPQVVDFKAPWIRMTMKESISVYGGVDVDLHADHELRKILETQTSLPEKTYVHASRGELIALLFDELVCDKLIAPHHITDHPLETTPLCKTLRSGDETLVERFESFCLGKELCNAYSELNDPLQQRKLLEEQMRKKALNPDSEYHPIDEEFLEALCQGMPPAGGFGIGIDRLVMMLTDAASIRDVLFFPVMRRIEAKKD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGA_PHOLL
Sequence: MKERSTELVEGFRHSVPYINAHRGKTFVIMLGGEAIAHENFTNIINDIGLLHSLGIRLVVVYGARPQIEQNLADHHYEPVYHKHTRVTDNKTLELVKQSAGLLQLDITARLSMNLNNTPLQGANINVVSGNFIIAQPLGVDDGVDYCHSGKIRRIDEHAINRQLDNGAIVLIGPVAVSVTGESFNLAFEDVATQLAIKLQAEKLIGFCSTQGVQDKDGKILSEVFLNQAPELIKELEVKGDYYSGTVCFLRSAIKACRRGVRRSHLLSYQADGSLLQELFSRDGIGTQIVMESAEQIRRANINDIGGILELIRPLEQQGILVRRSREQLEREIDKFIIIERDNLTIACAALYPYPEEKIGEMACLAVNPKYRSSLRGEVLLNRIAEHAKQLGLEKLFVLTTRSIHWFQERGFEPAELSMLPIQKQVLYNYQRRSKILMLNLEPQPGFT
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_ALIF1
Sequence: MSENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTMEERVKTNYDHPNALDHELLCEHLEQLMRGEAVNIPTYSYTEHTRTSEVDVMTPKKVIILEGILLLTDPRLRNLMHASVFMDTPLDICLLRRARRDVEERGRTMESVFEQYQKTVRPMFMQFIDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA1_VIBPA
Sequence: MAKKKKLTKGQVRRVRSNQQKRLKKQEESIQWDENMLGASKQGLVITRFGQHADIEDLETGEVQRCNLRRGIESLVSGDRVLWREGLESMAGISGVVEAVEPRTSMLTRPDYYDGLKPVAANIDQMVIVSSVLPELSLNIIDRYLVAAETLNIAPLLVLNKVDLLEVDDRAMYEEWLKEYERIGYKVLFVSKNSGEGISDLEVQLRDRINIFVGQSGVGKSSLVNALMPELEQEVEEGAISENSGLGQHTTTAARLYHIPTGGDLIDSPGVREFGLWHLEAEEVTKAFVEFRPYLGGCKFRDCKHNDDPGCILREAVEKGEVSEVRFENYHRILESMMENKANRQYSRNKKADL
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATRAP_PONAB
Sequence: MELPAVNLKVILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQRDSIDAISMFLGGLLATIFLDIVHISIFYPRAGLTDTGRFGAGMAILSLLLKPLSCCFVYHMYRQRGGFLGSSQDRSAYQTIDSAEAPANAFAVPEGRGQDARGY
What is the function of this protein?
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation.  Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity (By similarity).
What are the official names of this protein?
Type-1 angiotensin II receptor-associated protein, AT1 receptor-associated protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles.
Protein: RECF_COXB1
Sequence: MPYIGSLKVNQFRNLADVDITPHSQFNFFFGQNGAGKTSILESIYYLSVGRSFRTHLPQRLIQDNTDRFLIFITLYNGTQFIPLGVERDCQGDRCLRINGETASSWSLAAKRLPLCSLSAMSHRFLLDGPRVRRQFLDWLMFHVEPSFFSIWQRLQRSLKQRNASLKAKLPLGEITHWDKMLVEDGERLHQLRQNIVTEFKPLFTQMLQQFLPAYPLIGHYFRGWSEKYSLMEQLQINLKQDLQRGYTQAGPQRADFRLTLRDLPAQDILSQGQQKLVTYALHFAQGLLLKEKTGISPIYLIDDLPAELDANKRDCVIDLVNCLESQVFISGIDPNEIRLPPHSTLFHVKHGKVAAL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FYV1_HUMAN
Sequence: MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERAEGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALDTRRKAEPTFGGHDPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQKEYLISDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENGEKQAMERLLSANHNHMMALLQQLLHSDSLSSSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLMQNPSFHSLIEGRGHEGAVQEQYGGGSIPWDPDIPPESLPCDDSSLLELRIVFEKGEQENKNLPQAVASVKHQEHSTTACPAGLPCAFFAPVPESLLPLPVDDQQDALGSEQPETLQQTVVLQDPKSQIRAFRDPLQDDTGLYVTEEVTSSEDKRKTYSLAFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDYFAEQVYWSPLLNKEFKEMENRRKKQLLRDLSGLQGMNGSIQAKSIQVLPSHELVSTRIAEHLGDSQSLGRMLADYRARGGRIQPKNSDPFAHSKDASSTSSGQSGSKNEGDEERGLILSDAVWSTKVDCLNPINHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLERYCFRPSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGYQHTILTYSWCRICKQVTPVVALSNESWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHHDYHQYFSYNQMVASFSYSPIRLLEVCVPLPKIFIKRQAPLKVSLLQDLKDFFQKVSQVYVAIDERLASLKTDTFSKTREEKMEDIFAQKEMEEGEFKNWIEKMQARLMSSSVDTPQQLQSVFESLIAKKQSLCEVLQAWNNRLQDLFQQEKGRKRPSVPPSPGRLRQGEESKISAMDASPRNISPGLQNGEKEDRFLTTLSSQSSTSSTHLQLPTPPEVMSEQSVGGPPELDTASSSEDVFDGHLLGSTDSQVKEKSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEYRNALEELSKATQWNSAEEGLPTNSTSDSRPKSSSPIRLPEMSGGQTNRTTETEPQPTKKASGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGTENQGVEPQDEVDGGDTQKKQLINPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLGLNC
What is the function of this protein?
(Microbial infection) Required for cell entry of coronaviruses SARS-CoV and SARS-CoV-2, as well as human coronavirus EMC (HCoV-EMC) by endocytosis.
What are the official names of this protein?
1-phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase, FYVE finger-containing phosphoinositide kinase, PIKfyve, Phosphatidylinositol 3-phosphate 5-kinase type III, PIPkin-III, Type III PIP kinase, Serine-protein kinase PIKFYVE.
Protein: RL9_CLOB1
Sequence: MKVILLKDVKSLGKKGDLVNASDGYARNYLIPKKLAEQATENNVHILNNKKEAERRQKLKELEEAQKLAKSLMGKEIKFKVKIGENGRLFGSITSKDISEKLKEQYNMNIDKKKIVAETIRQTGVYEAEIKIYPEVSTKVKVSVLEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GLSA2_CLOPE
Sequence: MKNFLESLIENNRQYVEHGKLASYIPELEKANKEDLGIYIVTLDGKEVGAGEYDKKFTIQSISKVITLMLAILDNGKDRVFSRVGVEPTGDSFNSIVSLERKPSKKPFNPMVNSGAILTTSLIEGDSEEEKFERILEFTRKVTGNDDIQLNEDVYLSEKETGDRNRALAYFMKSNGVIEGNIDDILDLYFKQCSLEVNAKDLARFGAMLANDGVLPWNGERVISREICRIIKTIMVTCGMYDDSGKFAVHIGIPAKSGVGGGIMAAVPRRMGIGIFGPSLDDKGNSIAGTHVMKDLSEELDLSIF
What are the official names of this protein?
Glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: VPP1_RAT
Sequence: MGELFRSEEMTLAQLFLQSEAAYCCVSELEELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEMGRGAPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTHGFQNIVDAYGIGTYREINPAPYTVITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSMVFSGRYIILLMGLFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFTIGNWTEETLLGSSVLQLNPAIPGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMSSLFGYLVILIFYKWTAYDAHSSRNAPSLLIHFINMFLFSYPESGNAMLYSGQKGIQCFLIVVAMLCVPWMLLFKPLILRHQYLRKKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEPTEDEVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLHVRSLAGGLGLFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIREGKFDE
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:32165585).  V-ATPase is responsible for the acidification of various organelles, such as lysosomes, endosomes, the trans-Golgi network, and secretory granules, including synaptic vesicles (PubMed:32165585).  In certain cell types, can be exported to the plasma membrane, where it is involved in the acidification of the extracellular environment (PubMed:32165585).  Required for assembly and activity of the vacuolar ATPase (By similarity).  Through its action on compartment acidification, plays an essential role in neuronal development in terms of integrity and connectivity of neurons (By similarity).
What are the official names of this protein?
V-type proton ATPase 116 kDa subunit a 1, V-ATPase 116 kDa subunit a 1, Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit, Vacuolar adenosine triphosphatase subunit Ac116, Vacuolar proton pump subunit 1, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Melanosome.
Protein: MTX2_MOUSE
Sequence: MSLVAEAFVSQIAATEPWPENATLYQQLRGEQILLSDNAASLAVQAFLQMCNLPVKVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYLQWCDEATVGEITIARYGSPYPWPLNHILAYQKQWEVKRKMKAIGWGNKTLDQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLYTILTTQLTSDELSEKVKNYSNLLAFCRRIEQHYFEDWGKGRLS
What is the function of this protein?
Involved in transport of proteins into the mitochondrion.
What are the official names of this protein?
Metaxin-2, Mitochondrial outer membrane import complex protein 2.
What is the protein family that this protein belongs to?
Belongs to the metaxin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Mitochondrion.