PharMolix/UniProtQA huggingface dataset:
Protein: GPMA_METS4
Sequence: MERLLVLARHGQSEWNLKNLFTGWRDPDLTEVGIAEARAAGRRLKAKGIRFDICFTSALTRAQRTAALILEELGQPDLPTIADEALNERDYGDLSGLNKDDARARWGKDQVHIWRRSYDVPPPGGESLKDTVARVLPYTMREILPRVMRGERVLVAAHGNSLRALVMVLDGLTTETIPGLELWTGVPLVYRLKADTTVESKEVLDKDA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PPIB_CRYNJ
Sequence: MNTSHPIPTTMASKSFLSLLVALFVAICFVLSPGVDAAKGPVITNKVYFDIEHGGKPLGRIVMGLYGKTVPKTAENFRALATGKNSDGEDLGYGYEGSSFHRIIKNFMIQGGDFTKGDGTGGKSIYGSKFPDENFKLKHTGPGVLSMANAGRDTNGSQFFICTVKTAWLDNRHVVFGHVLEGMDVVYAMENVKTSRGDKPVEPITIAASGELPIEHEVDEQGNQVPFRIEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase B, PPIase B, Rotamase B.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: HTPX_BORPA
Sequence: MKRIFLFLITNLAVMVVLSATMRILGVDRFLTAQGLNLTGLLIFSAVIGFTGAIISLLMSKPMAKWSTGARVIDPNAPANQREAWLLDTVHQLADRAGIGRPEVAIYQGEPNAFATGAFRNDSLVAVSTGLLDSMTEEEVAAVLGHEVAHVANGDMVTLTLIQGVVNTFVVFLARVVGYFVDRAILKNERGVGLGYYATVIVCEIVFGILASIIVAWFSRQREYRADAGSAHLMGSREPMIRALARLGGLEPGELPKSFEASGISGKNGISAMFASHPPIQARIAALQHARLG
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GARS_HUMAN
Sequence: MPSPRPVLLRGARAALLLLLPPRLLARPSLLLRRSLSAASCPPISLPAAASRSSMDGAGAEEVLAPLRLAVRQQGDLVRKLKEDKAPQVDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETGKKETIEE
What is the function of this protein?
Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP) (PubMed:17544401, PubMed:28675565, PubMed:24898252).  Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.  Thereby, may play a special role in Ap4A homeostasis (PubMed:19710017).
What are the official names of this protein?
Glycine--tRNA ligase, Diadenosine tetraphosphate synthetase, Ap4A synthetase, Glycyl-tRNA synthetase, GlyRS, Glycyl-tRNA synthetase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, axon. Secreted. Secreted, extracellular exosome. Note=In transfected COS7 cells, not detected in mitochondria, nor in Golgi apparatus (PubMed:17035524). Secreted by motor neuron, possibly through the exosome pathway (By similarity). SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion. Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Cell projection, axon.
Protein: FGF4_MOUSE
Sequence: MAKRGPTTGTLLPRVLLALVVALADRGTAAPNGTRHAELGHGWDGLVARSLARLPVAAQPPQAAVRSGAGDYLLGLKRLRRLYCNVGIGFHLQVLPDGRIGGVHADTRDSLLELSPVQRGVVSIFGVASRFFVAMSSRGKLFGVPFFTDECKFKEILLPNNYNAYESYAYPGMFMALSKNGRTKKGNRVSPTMKVTHFLPRL
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.  Is essential for survival of the postimplantation mouse embryo.  Required for normal limb and cardiac valve development during embryogenesis.
What are the official names of this protein?
Fibroblast growth factor 4, FGF-4, Heparin-binding growth factor 4, HBGF-4, K-fibroblast growth factor.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: NS3_CVHNL
Sequence: MPFGGLFQLTLESTINKSVANLKLPPHDVTVLRDNLKPVTTLSTITAYLLVSLFVTYFALFKPLTARGRVACFVLKLLTLFVYVPLLVLFGMYLDSFIIFSTLLFRFIHVGYYAYLYKNFSFVLFNVTKLCFVSGKCWYLEQSFYENRFAAIYGGDHYVVLGGETITFVSFDDLYVAIRGSCEKNLQLMRKVDLYNGAVIYIFAEEPVVGIVYSSQLYEDVPSIN
What are the official names of this protein?
Non-structural protein 3, Protein 3, ns3, Accessory protein 3a.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: COAW_BACHK
Sequence: MESTIGIDAGGTLTKIAYLNEKKKLTFEKFYSNEQDKIIDWLKKQISIKQICITGGKAKQLQQLLSDSYKIVELNEFEATLVGVRYILKEEKYDINNFVLTNIGTGTSIHYIYNDRYIRAGGTGVGGGTIMGLSKLLTNIDHFEDVIPLTKVGSRKDLDITVGDIYGGILSPIDNSLTASNFGKAATIESNYNNSDILATVQGLVGEVVTALSLQFAETKNIDHIIYIGSTLCNNIHLQNIISSYTKYQNKTPIFLRDGGNSGAIGALLHATNKKS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type II pantothenate kinase, PanK-II, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type II pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_SALDC
Sequence: MTPEHLPTEQYEAQLAEKVARLQSMMAPFSGLVPEVFRSPVSHYRMRAEFRLWHDGDDLYHIMFDQQTKSRIRVDTFPAASQLINTLMKAMIAGVRDNHALRHKLFQIDYLTTLSNQAVVSLLYHKKLDEEWREAATALRDALRAQGLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALEVTKDSKGDLLELYCGNGNFSLALARNFNRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKRYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHTVSRLALFDQFPYTHHMECGVLLTAR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: PANB_ACIF5
Sequence: MHKKIARWVQDKKSGIKRAVVTAYDYPFARLAAEAGVHGILVGDSLGMVVGGGSDTLGVTLEQMAYHTGMVVRGAGDCLVFADLPFGSYEKGPEQAWAAAVTLLRAGADVVKLEGGAEMASTVAFCTERGINICAHIGLTPQRVRQWGSFQRQGTDADSARRLQADAGALAEAGARFLVLEAVPDALAANITRDIAIPTIGIGAGPDTDAQVLVIHDLLGLGTESPPFARRYIEGGRIMRDALAEYVREVGNSEFPPRRKR
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGFB2_CHICK
Sequence: MHCYLLSVFLTLDLAAVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPDEYPEPEEVPPEVISIYNSTRDLLQEKANHRAATCERERSDEEYYAKEVYKIDMQPFYPENAIPPSYYSLYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNSKARVSEQRIELYQVLKSKELSSPGQRYIDSKVVKTRAEGEWLSFDVTEAVHEWLHHRDRNLGFKISLHCPCCTFVPSNNYIIPNKSEEPEARFAGIDDYTYSSGDVKALKSNRKKYSGKTPHLLLMLLPSYRLESQQPSRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYHANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS
What is the function of this protein?
Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity).  Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains remain non-covalently linked rendering TGF-beta-2 inactive during storage in extracellular matrix (By similarity).  At the same time, LAP chain interacts with 'milieu molecules', such as LTBP1 and LRRC32/GARP, that control activation of TGF-beta-2 and maintain it in a latent state during storage in extracellular milieus (By similarity).  Once activated following release of LAP, TGF-beta-2 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal (By similarity).
What are the official names of this protein?
Transforming growth factor beta-2 proprotein.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix. SUBCELLULAR LOCATION: [Transforming growth factor beta-2]: Secreted.
Protein: VIRBA_AGRT9
Sequence: MNNDSQQAAHEVDASGSLVSDKHRRRLSGSQKLIVGGVVLALSLSLIWLGGRQKKVNDNASPSTLIAANTKPFHPAPIEVPPDTPAVQEAVQPTVPQPPRGEPERHEPRPEETPIFAYSSGDQGVSKRASQGDMGRRQEDKRDDNSLPNGEVSGENDLSIRMKPTELQPSRATLLPHPDFMVTQGTIIPCILQTAIDTNLAGYVKCVLPQDIRGTTNNIVLLDRGTTVVGEIQRGLQQGDERVFVLWDRAETPDHAMISLTSPSADELGRPGLPGSVDSHFWQRFSGAMLLSAVQGAFQAASTYAGSSGGGMSFNSFQNNGEQTTETALKATINIPPTLKKNQGDTVSIFVARDLDFFGVYQLRLTGGAARGRNRRS
What is the function of this protein?
VirB proteins are suggested to act at the bacterial surface and there play an important role in directing T-DNA transfer to plant cells.
What are the official names of this protein?
Protein virB10.
What is the protein family that this protein belongs to?
Belongs to the TrbI/VirB10 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PTRD1_MOUSE
Sequence: MHRKVRPASLMIRKMACSGVEPQILVQYLVLRKDLSQAPFSWPTGALVAQACHAATAALHLHRDHPHTAAYLRELGRMRKVVLEAADETTLKELAETLQQKNIDHTLWLEQPENIATCIALRPYPKEEVSQYLKKFRLFK
What are the official names of this protein?
Putative peptidyl-tRNA hydrolase PTRHD1, Peptidyl-tRNA hydrolase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family. PTRHD1 subfamily.
Protein: NCPP_ECOSE
Sequence: MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQPFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENASQRGEARSATLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVILALSPFHNAVY
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: CIPK7_ORYSJ
Sequence: MAATKSKAAKKGAPLLGKYELGRLLGRGTFAKVYHARSLAPGADPVAVKVLDKPDLAAAGAGMATRVLREVAAMRRLRHPNVLRLHEVLATRSKVYLVMELAPGGDLLSRLASLPSRRLPEHAAQRVFLQLVSALIYCHARGVSHRDVKPQNVLLDAHGNLKVSDFGLAALPDSLRDDGRLHTACGTPAFAAPEVLRRKAYDGAKADAWSCGVILFVLLAGHLPFDDSNIADMCRKAHRREYALPRWVSQPARRLVSRLLDPNPATRLAVAELATHPWFKRSLSLDSQLGSLLGGQPERELAFQAPPPLNAFDIISMSPGLDLSGLFGESKRRREKRFVTTASPERTVERLGQAGAKLGYFMVGKKGVERLPLGGLSGLVAMSMEMSEVSPSMMLVELRLEGGDDGDGDGGAEEFGWEELRAELGDDVVMAWHGCDGGKKDKEGILL
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting protein kinase 7, OsCIPK07.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: PII2_ARATH
Sequence: MLWQTFFSSLLLLSLLFGCNGDESLPEVTDSEEAPMDKREREALYSAIQGFVGDSWNGSALYPDPCGWTPIQGVSCDIYNDLWYVTDLSLGLIYENSLPCSSSLQIRPELFELKHLRSLSFFNCFISPMVIAKEELWTNFASNLESLEFRSNPGLIGELPETIGNLTKLKSLVVLENGFSGELPASICNLKRLKRLVFAGNSFAGMIPNCFKGLKELLILDLSRNSFSGTLPTSFGDLVSLLKLDLSNNLLEGNLPQELGFLKNLTLLDLRNNRFSGGLSKNIENIQSLTELVLSNNPMGEEDMVGTNWGKMSNLVVLDLSKMGLRGEIPTSLTNLKRLRFLGLNNNNLTGFVPSKKLEALPCLGALYINGNNLTGELRFSTKFYEKMGRRFKASKNPNLCQPLEMVMSESHKHLSPLGVKPCT
What is the function of this protein?
Required for growth promotion and enhanced seed production mediated by the endophytic fungus Piriformospora indica.
What are the official names of this protein?
Piriformospora indica-insensitive protein 2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side.
Protein: UREF_YERPY
Sequence: MNASDLIRIMQFGDSVLPVGAFTFSNGVESAIQTGIVHDVATLKGFVLTALKQAASCDGMGVVAAHRAVVADDRDGIIRADWAVNNRKLNEESRLMATRMGKKLAEMSIHVVEHPLISWWLEQIKNGNTAGTYPVTQAVVMAAQGIGQREVVVMHQYGVAMTILSAAMRLMRVTHFDTQHILFELNHDIEKFCDIAEIGDINQMSSYVPIVDVLAAVHVKAHVRLFSN
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCMBP_BOVIN
Sequence: MPCGEDWLSHPLGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMVQDMFDPEFYMGVYETVNRNTKARVLHFGKYRDVAECGPQQEVDLNSPRTTTLERQTFYCVPVPGESMWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHMGARQAGNVGGLQWCGEPKRLETEASSGQQLSSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGILSVDPVLSILNNDERDASSLLDPMECTDMAEEQRVHSPPASLVPRIHVVLAQKLQHINPLLPACLNKEESKTCKFVSGFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPRNSTFTEHLYRIIQHLVPASFRLQMTIENMNHLKFIPHKDYTANRLVSGLLQLPSNTSLVIDETLLEQGQLDTPGVHNVTALSNLITWQKVDYDFSYHQMEFPCNINVFITSEGRSLLPADCQIHLQPQLMPPNMEEYMNSLLSAVLPSVLNKFRIYLTLLRFLDYSISDEITKAVEDDFVEMRKNDPQSITADDLHQLLIVARFLSLSAGQTTLSRERWLRAKQLESLRRARLQQQKCVNGNEL
What is the function of this protein?
Associated component of the MCM complex that acts as a regulator of DNA replication.  Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA.  Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex.  Required for sister chromatid cohesion (By similarity).
What are the official names of this protein?
Mini-chromosome maintenance complex-binding protein, MCM-BP, MCM-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MCMBP family.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex (By similarity).
Protein: RL23_PSYIN
Sequence: MISEARLLQVILAPHISEKGTLSAENHNTMVFKVAGTATKAEIKAAVQKLFEVEVTGVRTLNVKGKTKRTGQRVGRRSDWKKAYVSLVEGADIDFAGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: YWBA_BACSU
Sequence: MSTFTRVMEEKIMPVAGKIAGQRHLSALRDGIILTMPLIIIGSVFLILTSLPIPGYADFMASVFGNEWADKLGYPVNASFDIMAMIAAFGIAYRLAESYGVDALSAGAISIAAFLLATPFEVPFTPHGSTESIMVGGGIPITLLGSKGLFVAMLIALFSTEIYRYIIQKNIVFKMPDGVPPAVSKSFVALIPGFIIVLLVWLARLLIEMTPFQSLHNVVGDLLGTPLSILGGSLGGSLIAEFVQMLLWSCGIHGASIIGGIMAPIWYGAMDANRLAFQAGEALPSIFTTQFFQIWINVGGSGATLALVLTMLVRSRSKQMKQLGRLGIGPALFNINEPIIFGMPIVMNPLLIVPFIIAPLLTITATYIGMSTGLVARPAGIAVPWTMPPLISGYLATGGKVSGAVMQLVNLLITCAIYYPFFRIWDHQKWREESAVESGDKNVM
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
What are the official names of this protein?
Putative permease IIC component YwbA, Putative PTS system EIIC component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VLMR_STRVF
Sequence: MTPSAAATGHEAADEQRLRELRGLTRQLPTGVAVVTAQDGEVAHGATVSTVSVLSQQPLRIGVSLRRGSYLTGLIRQRRVFALNVLSSRQSAVADWFANPERPRGWRQFDYVRWTAHPKAGMPVLEDALAQLHCRLTDLIPLGASDDLLVAEVLDGRGRNGRPLVNFNGRLHDVEFRGVVRVSRDQPSAVTSLE
What is the function of this protein?
Involved in the biosynthesis of the azoxy antibiotic valanimycin, which has an antitumor activity.  Catalyzes the reduction of FAD/FMN to FADH(2)/FMNH(2) which are subsequently used for the hydroxylation of isobutylamine by the isobutylamine N-hydroxylase VlmH.  It can reduce either FAD or flavin mononucleotide (FMN) but prefers FAD.  The enzyme has a strong preference for NADPH as acceptor.
What are the official names of this protein?
NADPH-flavin oxidoreductase, FAD reductase (NADPH), FMN reductase (NADPH), Isobutylamine N-hydroxylase, reductase component.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family.
Protein: RL3_METBF
Sequence: MASIHRPKRGSLAFSPRKRAKSHIPRFRAWPEATGEPRLQGFAGYKVGMTHVIMVDDTKNSLTQGMEISVPVTIIETPAIRVAAIRAYAEDTAGEKAIAEVWATDLDPELKRRIPVPKGDNMAETLGNIGKMIEEGKVSDIRAVTYTLPKSLTGVPKKTPDIMESGISARDLNTKFEYAKSILGTLVSITDVFKTGTLIDTAAITIGKGTQGPAKRWGIQLMKGKHSRQGSLRQIGTLGGFGLRRVSWRVPQMGQTGYHQRTEFNKRILKIGSDGEEVTPEGGFINYGLVRGDYVLIKGSVPGPSKRLIRLRDPIRAKKADLGEPNILHISRESKQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CRCB_HAEI8
Sequence: MQALLFISYGAILGASLRWAIGLLFNPLFSSFAFGTLIANLLGCLIIGVLLGFFWQFPQISSEWRLFLITGFLGSLTTFSSFSSEVVELFFNDKWLNGFCVLMMHLFGCLAMTVLGIWIYKICSQLLS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNTH_SALCH
Sequence: MTDNRVENSSGRAARKLRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELFFSQPDMAQLGKGMVIPALPNPEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGTRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGIADLDQAYLTLEPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFVRFHIPLWVRRTITMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSNATLMGELVNTRRVKQVGWIIVVLVVALNIWLLVGTVMGLS
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTASE_MBVLF
Sequence: MSKYLATSVRLCLMVCIVGWLLMPSYKELDGWCSSLSSLERDKSNWLLTGLSTWFCIVPSGTDQSSLVSYFSPLEKLSKFVQDLDLDFVKLWWLETITLINTLNTTEKLLSGVTFSVVLWYPRILVTVLMLVWKLWFPVRFLVVASSLLCLRILVWPFEVIADVILETCAWFTRKYHKLMDVIEDLMMIPQRVMEWCSGNTAKMVVPTVASCVSESIESKLDRILMALGRKGTVLEAAQPGSDFVECEQWPNGLVAIRRHDGRIVGMGFLVVLNGKWRLVTAAHVARECKRGIMLSAGIDSKTVTFQDLDVVLQTQVDACIMNVPAGTAASLGVRKVVINRTPSESKVVRTYGYNSGKFCMSEGLVGTTSANMGFRHGCSTLRGWSGTPIYRDNKVVGIHSRCNGIYENFGLSLDLLVGRLESEETDRYARTMEEFNTEDRPVTPPMEFSWEFEEKFERVRSTRKSFARIESEVATFTATKLSGFDWTDDAPMDFDELPVFESTMVSVFQERPLGGLPISNGNKAEEKKITSEALEPSKSSTPEAAKHTRRRRRNKKKSKNSETGHGPEEQSQQQSRPSSPIPDDSAPVSSPPVSPPSTGSVPKSWTQAYTQKLVLLLGSMDGQSKEKVDLAILEAKSFASALFPPSKPKSSEESEK
What is the function of this protein?
Putative serine protease.
What are the official names of this protein?
Putative serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S39B family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: RECA_MESH7
Sequence: MTEINEKSLLKQALAEIKKKFGNESIMVLGEKPPIDTEVFSSGSMAIDMALGIGGFPKGRIIEIYGPESSGKTTISLHAIAEVQKQGGIAAFIDAEHSIDPQYAKNLGIDIDNLILSQPDSGEQALDIVDTLTKTKAIDLIVVDSVAALVPMAELQGEMKDQVIGAQARLMSKALRKITASLNKNGTTVIFINQIREKVGVIFGNPETTPGGRGLKFYASIRLDVRKIQQITSGNDITGHSVKIKVVKNKLAIPFKTALVEIVFAKGISKSAEIAQLGEELGILVRKGSWFAYKGENIAQGKVNLKLLLENNTKLFNEIKDQIIEKLKENQQQSQTL
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO11_THESM
Sequence: MKIEVIKRDKNLLEFYLVGEDHTFANLLSETLHENKHVTFAAYTIEHPVLMARKPRFRISTDGKITPEKALEEAAQKIFDRAKDVLEVWEGVIKK
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEBP4_HUMAN
Sequence: MGWTMRLVTAALLLGLMMVVTGDEDENSPCAHEALLDEDTLFCQGLEVFYPELGNIGCKVVPDCNNYRQKITSWMEPIVKFPGAVDGATYILVMVDPDAPSRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQAPSPPAHSGFHRYQFFVYLQEGKVISLLPKENKTRGSWKMDRFLNRFHLGEPEASTQFMTQNYQDSPTLQAPRERASEPKHKNQAEIAAC
What is the function of this protein?
Promotes AKT phosphorylation, suggesting a possible role in the PI3K-AKT signaling pathway.
What are the official names of this protein?
Phosphatidylethanolamine-binding protein 4, PEBP-4, hPEBP4, Protein cousin-of-RKIP 1.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCD21_ORYSJ
Sequence: MPADDDDASYLLCAEDAGAAVFDVAVDISTCTTEDDECCSVGGEELYSAASIAELIGGEAEYSPRSDYPDRLRSRSIDPAARAESVSWILKVQEYNGFLPLTAYLAVNYMDRFLSLRHLPEGQGWAMQLLAVACLSLAAKMEETLVPSLLDLQVECSRYVFEPRTICRMEFLILTALNWRLRSVTPFTFIDFFACKHISNAMVQNANSDIQFLDHCPSSMAAAAVLCATGETPSLAFVNPELAVNWCIGLAEEGISSCYQLMQQLVIGNVQRSAAAAAAVNLFSDEGLSYDSSSPPPPKRRKRSPPGT
What are the official names of this protein?
Cyclin-D2-1, G1/S-specific cyclin-D2-1, CycD2;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.