PharMolix/UniProtQA huggingface dataset:
Protein: DPOLB_MOUSE
Sequence: MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEIKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVHFITDTLSKGETKFMGVCQLPSEKDGKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
What is the function of this protein?
Repair polymerase that plays a key role in base-excision repair.  Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap.  Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases (By similarity).
What are the official names of this protein?
DNA polymerase beta.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Cytoplasmic in normal conditions. Translocates to the nucleus following DNA damage (By similarity).
Protein: POT13_ARATH
Sequence: MFHVEEESSGGDGSEIDEEFGGDDSTTSLSRWVFDEKDDYEVNEDYDDDGYDEHNHPEMDSDEEDDNVEQRLIRTSPAVDSFDVDALEIPGTQKNEIEDTGIGKKLILALQTLGVVFGDIGTSPLYTFTVMFRRSPINDKEDIIGALSLVIYTLILIPLVKYVHFVLWANDDGEGGTFALYSLICRHANVSLIPNQLPSDARISGFGLKVPSPELERSLIIKERLEASMALKKLLLILVLAGTAMVIADAVVTPAMSVMSAIGGLKVGVGVIEQDQVVVISVSFLVILFSVQKYGTSKLGLVLGPALLLWFFCLAGIGIYNLVKYDSSVFKAFNPAYIYFFFKRNSVNAWYALGGCVLCATGSEAMFADLSYFSVHSIQLTFILLVLPCLLLGYLGQAAYLSENFSAAGDAFFSSVPSSLFWPVFLISNVAALIASRAMTTATFTCIKQSIALGCFPRLKIIHTSKKFIGQIYIPVLNWSLLVVCLIVVCSTSNIFAIGNAYGIAELGIMMTTTILVTLIMLLIWQTNIIVVSMFAIVSLIVELVFFSSVCSSVADGSWIILVFATIMFLIMFVWNYGSKLKYETEVQKKLPMDLLRELGSNLGTIRAPGIGLLYNELAKGVPAIFGHFLTTLPAIHSMVIFVCIKYVPVPSVPQTERFLFRRVCPRSYHLFRCVARYGYKDVRKESHQAFEQILIESLEKFIRKEAQERALESDGDHNDTDSEDDTTLSRVLIAPNGSVYSLGVPLLAEHMNSSNKRPMERRKASIDFGAGPSSALDVEQSLEKELSFIHKAKESGVVYLLGHGDIRATKDSWFLKKLVINYLYAFLRKNSRRGITNLSVPHTHLMQVGMTYMV
What is the function of this protein?
Probable potassium transporter.
What are the official names of this protein?
Potassium transporter 13, AtKT5, AtPOT13.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABA_SHIDS
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAB_STAAR
Sequence: MSYSIGIDYGTASGRVFLINTTNGQVVSKFVKPYTHGVIEGELNGLKIPHTYALQNSNDYLEIMEEGISYIVRESKIDPVNIVGIGIDFTSSTIIFTDENLNPVHNLKQFKNNPHAYVKLWKHHGAYKEAEKLYQTAIENNNKWLGHYGYNVSSEWMIPKIMEVMNRAPEIMEKTAYIMEAGDWIVNKLTNKNVRSNCGLGFKAFWEEETGFHYDLFDKVDPKLSKVIQDKVSAPVVNIGEAVGKLDDKMAQKLGLSKDTMVSPFIIDAHASLLGIGSEKDKEMTMVMGTSTCHLMLNEKQHQVPGISGSVKGAIIPELFAYEAGQSAVGDLFEYVAKQAPKSYVDEAANRNMTVFELMNEKIKHQMPGESGLIALDWHNGNRSVLSDSNLTGCIFGLTLQTKHEDIYRAYLEATAFGTKMIMQQYQDWHMEVEKVFACGGIPKKNAVMMDIYTNVLNKKLIVMDSEYAPAIGAAILGAVSGGAHNSINDAVDAMKEPILYEINPEAEKVQRYETLFKAYKALHDIHGYKKANIMKDIQSLRVEG
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: METK_BACSU
Sequence: MSKNRRLFTSESVTEGHPDKICDQISDSILDEILKKDPNARVACETSVTTGLVLVSGEITTSTYVDIPKTVRQTIKEIGYTRAKYGFDAETCAVLTSIDEQSADIAMGVDQALEAREGTMSDEEIEAIGAGDQGLMFGYACNETKELMPLPISLAHKLARRLSEVRKEDILPYLRPDGKTQVTVEYDENNKPVRIDAIVISTQHHPEITLEQIQRNIKEHVINPVVPEELIDEETKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNIVAAELADSCEVQLAYAIGVAQPVSISINTFGSGKASEEKLIEVVRNNFDLRPAGIIKMLDLRRPIYKQTAAYGHFGRHDVDLPWERTDKAEQLRKEALGE
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_ACIBC
Sequence: MRDKIRLVSSAGTGYFYTTTKNKRTMPEKMEIKKFDPKIRQHVIFKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RSMH_SALHS
Sequence: MMENFKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAQTINDPRFSIIHGPFSALADYVAERELTGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTFGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLSVLAPGGRLSIISFHSLEDRIVKRFMREQSRGPQVPAGLPMTEAQLKKLGGRELRALGKLMPGEKEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAPA_MAGMG
Sequence: MSLTRRDFIKANAVPATAAAAGLATPAIAQPAKANIRWDKGVCRFCGTGCSVLVGVQDGRVVATQGDPDSPVNRGLNCIKGYFLSKIMYGEDRLTRPLLRMKDGKFDKNGEFQPISWDQAFDIMAEKWKEQLKKPDGVTRVGMFGSGQWTIWEGYAASKLYKAGFRSNNLDPNARHCMASAVAGFMRTFGIDEPMGCYDDIEQTDAFVLWGSNMAEMHPILWSRVTDRRLTHEGCKVAVLSTFEHRSFELADIPMVFTPQTDLAILNYICHYIISKNAYNKEFIDKHVNFKKGATDIGYGLRPTHALEKDQANAATPDKADPMTFDEFKAFVAEYTVEKVSKLSGVPADKLEALAKLYADPKVKVVSFWTMGFNQHTRGTWVNNMIYNVHLLMGKISEPGNSPFSLTGQPSACGTAREVGTFAHRLPADMVVMNDKHREIAERCWKLPAGTINPKIGYHAVLQHRMLKDGKLNAYWVMCTNNMQTAPNMNEEGYPGYRNPANFIVVSDPYPTVTALAADLILPTAMWMEKEGAYGNAERRTQFWAPEGQGSGRGRSDLWQIMEFSKRFKIEEVWPEELIAKKPELRGKTLFEVLYKNGQVDKFPLTELQAGFENDEAKAFGFYPQKGLFEEYASFGRGHAHDLAPFESYHKARGLRWPVVDGKETLWRFREGYDPYVKAGEGVKFYGKPDGKAWIFALPYAPAAESPDKDFDLWLSTGRVLEHWHSGSMTRRVPELHKSVPNAVLYMHPNDAAKRNLRNGDVVKVASRRGEVTTRIDTRGRNKPPEGLVFMPFFDESQLVNKLTLDATCPISKETDYKKCAVKVSKA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: ATRAP_MOUSE
Sequence: MELPAVNLKVILLVHWLLTTWGCLVFSSSYAWGNFTILALGVWAVAQRDSIDAIGMFLGGLVATIFLDIIYISIFYSSVATGDTGRFGAGMAILSLLLKPFSCCLVYHMHRERGGELPLRPDFFGPSQEHSAYQTIDSSSDAAADPFASLENKGQAVPRGY
What is the function of this protein?
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation.  Induces also a decrease in angiotensin II-stimulated transcriptional activity.  May play a role of negative regulator in cardiomyocyte hypertrophy induced by angiotensin II through an inhibition of p38 mitogen-activated protein kinase pathway.
What are the official names of this protein?
Type-1 angiotensin II receptor-associated protein, AT1 receptor-associated protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles.
Protein: EFTU_BACFR
Sequence: MAKEKFERTKPHVNIGTIGHVDHGKTTLTAAITTVLAKKGLSELRSFDSIDNAPEEKERGITINTSHVEYETANRHYAHVDCPGHADYVKNMVTGAAQMDGAIIVVAATDGPMPQTREHILLARQVNVPKLVVFMNKCDMVEDAEMLELVEMEMRELLSFYDFDGDNTPIIQGSALGALNGVEKWEDKVMELMEAVDTWIPLPPRDVDKPFLMPVEDVFSITGRGTVATGRIETGVIHVGDEIEILGLGEDKKSVVTGVEMFRKLLDQGEAGDNVGLLLRGVDKNEIKRGMVLCKPGQIKPHSKFKAEVYILKKEEGGRHTPFHNKYRPQFYLRTMDCTGEITLPEGTEMVMPGDNVTITVELIYPVALNIGLRFAIREGGRTVGAGQITEIID
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG1A_ARATH
Sequence: MESARLVGDYALGPRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISILSTIDHPNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPESMAETFCGSPLYMAPEIIRNQKYDAKADLWSAGAILFQLVTGKPPFDGNNHIQLFHNIVRDTELKFPEDTRNEIHPDCVDLCRSLLRRNPIERLTFREFFNHMFLREPRQIPDVEHSGFSTCTGKSLLPSAQPSTSTNRFKSSAENVHKHGSSSSASNSQISMPHTSFEKTRKDTEGQCSSNQSGVVDSLELIEREYVLVNRPSASLEGSSDCFDTSLQDSGFPNILPRNEKVSSSSLEAQKPLSDVSGPRPASVSYLLTEVQRLTIVHPPTKLQLLHQYAQALTELASEMGNTGQVKESFAVTLVVLAVWRKALEICDSWMMSVGENEVNPDPTTAPETSIPDLNSPAPAKTWVTQEFVTALNQAENLSTQLNETSAATHMPDAMETIYERALAYGKSGGAEEYLSNKESAATLYKKAILLLSFIIEEAVTLSLNPSFSLTPDDKKRILYYISNLQHRRSHL
What is the function of this protein?
Serine/threonine protein kinase involved in autophagy in a nutritional condition-dependent manner.  The ATG1-ATG13 protein kinase complex regulates downstream events required for autophagosome enclosure and/or vacuolar delivery.  Becomes a target of autophagy under nutrient starvation.  Connects autophagy to plant nutritional status.
What are the official names of this protein?
Serine/threonine-protein kinase ATG1a, Autophagy-related protein 1a, AtAPG1a.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome.
Protein: TETR2_ECOLX
Sequence: MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLGTRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERETPTTDSMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS
What is the function of this protein?
TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA.  Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
What are the official names of this protein?
Tetracycline repressor protein class B from transposon Tn10.
Protein: MTXA_METAC
Sequence: MKTIAENWPPVRGDYVTGKPDSRIAVVTLASHLEAFPNAAIWGSSKTENLGVEKIIVNVISNSNIRYVLVCGTESRGHLAGHSLLAIHANGIDEKGRIVGSQGAIPFIENISREAVDRFQRQVTLLDRIGLNDPEEIRKIVEDYRDKGEVYPEEPVVVCAPKKRQASFAVPSSGDVIISEELVMDSMAGIICLAESL
What are the official names of this protein?
Putative methyltransferase Mtx subunit A.
What is the protein family that this protein belongs to?
Belongs to the MtrA family.
Protein: VKTB3_DABSI
Sequence: MSSGGLLLLLGLLTLWAELTPISGHDRPTFCNLAPESGRCRGHLRRIYYNLESNKCEVFFYGGCGGNDNNFSTRDECRHTCVGK
What is the function of this protein?
Serine protease inhibitor that inhibits plasmin and trypsin.
What are the official names of this protein?
Kunitz-type serine protease inhibitor B3, BPTI-3, Trypsin inhibitor 3, Trypsin inhibitor B3.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYE_ENTFA
Sequence: MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGEFIIRIEDTDQKRNIEDGEKSQLENLAWLGMEWDESPAHPGEYGPYRQSERKEIYQPLIDQLLSSNRAYKCYCTPEELEAEREAQQARGEMPHYAGTCANLTPSEQAAKEAAGLEPVIRFRVPRNTEYKFDDIVKGEITFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKISHVLRGDDHIANTPKQLMIYEAFEWTPPVFGHMTLIINSETGKKLSKRDETILQFIEQYRELGYLPEAMFNFIALLGWSPVGEEEIFSQEDLIKLFDEQRLSKSPAAFDAKKLEWINNQYMKQMDLSELTDMCIPYLVADGRVEENPSPEKIEWLKQLVSLYQPQMSYAAEIVELSNLFFNEHPVLDDAAKEFLQGETVPTVLHAFKEQLEALDVFDVPSIKAAIKAVQKETGVKGKNLFMPIRIAVSGQMHGPELGETIELLGKEKALDHLNKVL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLY_PSEAV
Sequence: MLKPHGLTPLALTGGILVSLLSVSLSAHAEIATDVATTGWATQNGGTKGGSRAAANNIYTVKNAAELKAALAASGGSNGRIIKERGVIDVSDGKPYTKTSDMKQRARLDIPGKTTIVGTSSSAEIREGFFYAKENDVIIRNLTIENPWDPEPVWDPEDGSAGNWNSEYDGLTVEGASNVWIDHVTFTDGRRTDDQNGTANGRPKQHHDGALDVKNGANYVTISYSVFRNHEKNNLIGSSDSKTPDDGKLKVTNHNSLFENISSRGPRVRVGQVHLYNNHHIGSTTHKVYPCVYAQGVGKGSKIFSERNVLDISGISGCSKVAADYGGSVYRDSGSLVNGSVISCSWSTSIGWTPPYSYTPLAADKVAADVKAKAGAGKI
What is the function of this protein?
Plays a role in bacterial invasion of plants.
What are the official names of this protein?
Pectate lyase, PL.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LCAT_RAT
Sequence: MGLPGSPWQWVLLLLGLLLPPATSFWLLNVLFPPHTTPKAELSNHTRPVILVPGCMGNRLEAKLDKPNVVNWLCYRKTEDFFTIWLDFNMFLPLGVDCWIDNTRVVYNRSSGHMSNAPGVQIRVPGFGKTYSVEYLDDNKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLAPRQQDEYYQKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLHFLLRQPQSWKDHFIDGFISLGAPWGGSIKPMRILASGDNQGIPIMSNIKLREEQRITTTSPWMFPAHHVWPEDHVFISTPNFNYTGQDFERFFADLHFEEGWHMFLQSRDLLAGLPAPGVEVYCLYGVGMPTAHTYIYDHNFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQAVHLLPMNGTDHLNMVFSNKTLEHINAILLGAYRHGTPKSPTASLGPPTKE
What is the function of this protein?
Central enzyme in the extracellular metabolism of plasma lipoproteins.  Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs).  The cholesterol ester is then transported back to the liver.  Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels.  Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins.  Required for remodeling high-density lipoprotein particles into their spherical forms (By similarity).  Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines (PubMed:8820107, PubMed:14636062).  Catalyzes the hydrolysis of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor or PAF) to 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) (By similarity).  Also catalyzes the transfer of the acetate group from PAF to 1-hexadecanoyl-sn-glycero-3-phosphocholine forming lyso-PAF (By similarity).  Catalyzes the esterification of (24S)-hydroxycholesterol (24(S)OH-C), also known as cerebrosterol to produce 24(S)OH-C monoesters (By similarity).
What are the official names of this protein?
Phosphatidylcholine-sterol acyltransferase, 1-alkyl-2-acetylglycerophosphocholine esterase, Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase, Platelet-activating factor acetylhydrolase, PAF acetylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into blood plasma (PubMed:8820107). Produced in astrocytes and secreted into cerebral spinal fluid (CSF) (By similarity).
Protein: SYD_HAEIE
Sequence: MMRTHYCGALNRNNIGQDVTLSGWVHRRRDLGGLIFIDMRDRDGIVQVCFDPKYQDALTAAAGLRNEFCIQIKGEVIARPENQINKNMATGEVEVLAKELRVYNASDVLPLDFNQNNTEEQRLKYRYLDLRRPEMAQRLKTRAKITSFVRRFMDDNGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFLTAPEVREIMERMVHGLWLDTIGVDLGKFPVMTWQEAMRRFGSDKPDLRNPLEIVDVADIVKDVEFKVFNEPANNPNGRVAVIRVPNGAEITRKQIDEYTQFVGIYGAKGLAWAKVNDINAGLEGVQSPIAKFLNEEVWKALAERVNAQTGDILFFGADKWQTTTDAMGALRLKLGRDLGLTRLDEWKPLWVIDFPMFERDEEGNLAAMHHPFTSPKDFSPEQLEADPTSAVANAYDMVINGYEVGGGSVRIFDPKMQQTVFRILGIDEEQQREKFGFLLDALKFGTPPHAGLAFGLDRLTMLLTGTENIRDVIAFPKTTAAACLMTEAPSFANPQALEELAIQVTKSE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPL1_DROME
Sequence: MVKTFQAYLPSTNRTYSCVHCRAHLASHDELISKSFQGSQGPAYLFNSVVNVACGQTEERVLLTGLHAVADIYCECCKTPLGWKYEHAYESSQKYKEGKFIIELAHMIKENGWD
What is the function of this protein?
Involved in regulating synaptic transmission in presynaptic neurons (PubMed:32461240).  In class IV dendritic arborization neurons (nociceptors), involved in regulating activation of their second-order neurons (SONs) and maintaining synaptic contact between nociceptors and their SONs (PubMed:32461240).
What are the official names of this protein?
Protein yippee-like, Protein yippee-like 3.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
Protein: LEUC_STRMU
Sequence: MSGKSIFDKLWDRHVITGKEGEPQLMYVDQHYIHEVTSPQAFQGLRDAGRKVRRPDLTFGTFDHNVPTVNIYDIRDVISKAQMDALARNVIEFNIPHADHGSENQGIVHMVGPETGRTQPGKFIVCGDSHTATHGAFGAIGFGIGTTEVEHVFATQTIWQVKPKKLLVKFTGKPQKGVYSKDYILALIAKYGVALGVGYVVEYIGDAVDALSMEERMTICNMSIEFGSKMGIMNPDQKTFDYLKNKACVPEDFETAVADWKTLVSDEDAHYDKVIELDVSQLAPMVTWGTNPSMGVAFGQAFPDIRDMNDKRAYDYMDMKPGQTAEDIELGYVFLGSCTNARLSDLKVAAKYVAGKHIAPNLTAIVVPGSRPVKQAAEKIGLDKIFLDAGFEWRDPGCSMCLGMNPDKVPEGMHCASTSNRNFEDRQGVGAKTHLCSPAMAAAAAIAGRFIDVRQLPEAQV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: COX1_RHOCA
Sequence: MWDYVKLVALGVVAAIAAYAASQARDLPYMVNMVEVALAAVIALIWVLRTMGDPKPSKDEYFDGVIRAGVIATTFWGIVGFLVAVVIAFQLAFPALNLEFGNGMLNFGRLRPLHTSAVIFAFGGNALIASAFYVVQRTSAARLFGGTALGWFVFWGWQLIIVTAATSYLLGGSQGKEYAELNWHLDILVAVVWVAYLIAFLGTIFKRKEPHIYVANWFYLSFIVTIAMLHIVNNLAVPVSIFGTKSVQLMAGVQDAMTQWWYGHNAVGFFLTAGFLGMMYYFVPKQAERPVYSYKLSIVHFWALIFLYIWAGPHHLHYTALPDWASTLGMVMSVILWMPSWGGMINGLMTLSGAWDKLRTDPVIRMMVVSIGFYGMSTFEGPMMSIKAVNSLSHYTDWTIGHVHSGALGWNGMITFGMLYFLTPRLWGRSGLYSLKLVSWHFWLATIGIVLYASAMWVTGIMEGLMWREVDAQGFLVNAFADTVAAKFPMYVVRGVGGVLYLLGGLIMAYNLWATVAKQPKTANLAVAVPAE
What is the function of this protein?
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Subunits 1-3 form the functional core of the enzyme complex.  Co I is the catalytic subunit of the enzyme.  Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B.  This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome BB(3) subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBL_PACAQ
Sequence: KASVGFKAGVKEYKLTYYTPEYEVKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTSYTKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFQAVDTLD
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CCZ1_XENLA
Sequence: MAFAGQDKRYAPSLLSFFIYNPKFGPREGEEEKKILFYHPNEVEQNEKIRNVGLCEAIVQFTRTFNPTKPAKSLHTQKNRQFFHEPEEGFWMVMVVKNPVAEKQKDGKTVLEYQEDELLDKVYSSVLQQCYRMYKLFNGTFGRAMEVGQVELLKDRLEKFFHRYLQTLHLHSCDLLDVFGGISFFPLDKMTYLKVQSFINRIEESLNIVKYTAFLYNDQLIWSGLEQEDMRILYKYLTTTLFPRYTEPELAGRDSPIRPEMPGNLQHYGRFLTGPLNLNDSEVKFRFPKIFVNTEDSYEELHLIVYKAMSASVCFMIDASVQLTVDFCRKLDSLVGPQLTVLASDICEQYNSNRRISGSEKEPQFKFIYFNHMNLAEKSTIHLRKTPNMSLTSVQPELMKILGDINSDFTRVDEDEEIIVKAMSDYWVVGKKSDQRELYVILNQKNSNLIEVNEEIKKLCATHFSNIFFLD
What are the official names of this protein?
Vacuolar fusion protein CCZ1 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCZ1 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: PSBT_CHAVU
Sequence: MEALVYTFLLVGTLGIIFFAIFFREPPRIIAKTKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.