PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_METPB
Sequence: MTTRTIDNIRNFSIVAHIDHGKSTLADRLIQQTGTVALRDMSEQMLDSMDIERERGITIKANTVRLEYKAEDGQDYVLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDASQGVEAQTLANVYQALDANHEIVPVLNKVDLPAAEPDRVKEQIEEVIGLDASEAVPISAKTGLNIEAVLEAIVKRLPPPKGDREAPLKALLVDSWYDVYLGVVVLVRIVDGVLKKGMTIRMMGADAAYGVDRIGVFRPKMADIGELGPGEVGFFTGSIKEVADTRVGDTITEDKRQTTQMLPGFKEVQAVVFCGLFPVDAADFENLRGAMGKLRLNDASFSYEMETSAALGFGFRCGFLGLLHLEIIQERLEREFNLDLISTAPSVVYRLMMRDGELKELHNPADMPDPMKIETVEEPWIRATILTPDDYLGGVLKLCQDRRGIQIDLNYVGKRAMVVYDLPLNEVVFDFYDRLKSISKGYASFDYHVSDYREGDLVKMSILVNAEPVDALSMLVHRTRAESRGRAMCEKLKDLIPRHLFQIPVQAAIGGKIIARETIRALSKDVTAKCYGGDISRKRKLLDKQKEGKKRMRQFGRVEIPQEAFIAALKMDD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TBPA_NEIGO
Sequence: MQQQHLFRLNILCLSLMTALPAYAENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGKLVKTADTLSKEQVLDIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGLAQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIRTGRHAGEIRAHEAAGRGVQSFNRLAPVDDGSKYAYFIVEEECKNGGHEKCKANPKKDVVGEDKRQTVSTRDYTGPNRFLADPLSYESRSWLFRPGFRFENKRHYIGGILERTQQTFDTRDMTVPAFLTKAVFDANQKQAGSLRGNGKYAGNHKYGGLFTSGENNAPVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQGIGLDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHKLLQAAFKKSFDTAKIRHNLSVNLGYDRFGSNLRHQDYYYQSANRAYSLKTPPQNNGKKTSPNGREKNPYWVSIGRGNVVTRQICLFGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNAGIVLKPADWLDLTYRTSTGFRLPSFAEMYGWRSGDKIKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKDGKEQVKGNPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVRVRDIKKRADRTDIQSHLFDAIQPSRYVVGSGYDQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYTVKKHFTLRAGVYNLLNHRYVTWENVRQTAAGAVNQHKNVGVYNRYAAPGRNYTFSLEMKF
What is the function of this protein?
Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host.  Acts as a TF receptor and is required for TF utilization.  Binds both apo- and holo-TF, via the TF C-terminus.
What are the official names of this protein?
Transferrin-binding protein A, TbpA, Transferrin-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: PIFO_HUMAN
Sequence: MCFSRADAADNYPFGTCQQRKLFPHFHPPNLIGNKFVPLRGSPHRGPGCYFSDGYGLAYDLSKIPTSIKGYTLGARTAVRFKPIQKEMTPHAGRYQKVSPQQEKHKQNFAPFNVLVPRFKNYPKDTYYPSPGAYNPEKKPPPKIAWPMKFGSPDWAQVPCLQKRTLKAELSTDKDFRKHRNRVAYLSLYYN
What is the function of this protein?
During primary cilia disassembly, involved in cilia disassembly.  Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/centrosome.  May act by stimulating AURKA activity at the basal body in a cell cycle-dependent manner.
What are the official names of this protein?
Protein pitchfork.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Golgi apparatus, trans-Golgi network. Cytoplasm. Note=Accumulates specifically at the basal body and ciliary necklace during the early steps of cilia assembly and disassembly, when structural, functional and regulatory proteins are delivered to cilia. At S phase, accumulates in vesicles and declines during mitosis.
Protein: OPS3_BEAB2
Sequence: MFYTFNAVMTDVVSAGRPARGQSTTTRSRNTQQSAPTSQNFRACRRCRQHRIKCSEKPCEPCRANNSKCVWTEEKPTAAVLTPISPANLAANRPMMAPAAGSTITKPIASHYASPTYTDGEDGGGEPWPLQHPCSCAQHPNTPNSCPSQSGDIRQQQIPCSQHASPASNASKTFHQFLEGLGMAVTAEEGELHQFPPLPSAEEGKTSTAAAGLLPSAPTASETLNWDGQLYFVRLFWMSLAPLFPIMPESEFEALYAADGPYLLGQRTIEGALINGMTALGIQCAEATGSGARILSCSPTAASRSSIEYFRRCRDVLRDQDTSTTTCVHTIRCYILLTLYHLQANQLEKAYYLAGLGVRRAHMGRFHLTPAAHSSARVADDRIRVWWLLSWLDVYCSLQLGRPAAVQRSSNPCPPPSSPPMRFTPMHADVVSRKEASLDNYRFVLSKLTMIVVEALDDVPVFQSLEEMHGSSTAGQSMARLSETIRQLETALDELPEQLLTRHGSRTPTNNGQTHRSRPTCSTMPHTNRQVTSSASSAALTVGLPDWLQRQRLILELHYLDACLVLQRPFVLWKQICSSDASITKHAESAFSRACSVLSMLHSIYSRSDILDRLTMVLPFIWNAIITIAAYVFVGSADDDKKTQLLKAMNNALAILEPLARINPDSLKVYQISQALAAELREASGGTDVVAMPPPPSAATSTSTTFTDDLFKSTFTGSLDLDEFLNDEVTMTDDFSELYSF
What is the function of this protein?
Transcription factor involved in regulation of gene cluster that mediates the biosynthesis of oosporein, a metabolite required for fungal virulence that acts by evading host immunity to facilitate fungal multiplication in insects (PubMed:26305932).  Binds oosporein cluster genes at a conserved 5'-CGGA-3' motif with the exception of OpS5 (PubMed:26305932).  The presence of this motif in the OpS3 promoter would suggest the formation of a positive feedback loop for self-activation (PubMed:26305932).
What are the official names of this protein?
Oosporein cluster regulator OpS3, Oosporein biosynthesis protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTH_SHEON
Sequence: MSEIKLIVGLANPGAEYVQTRHNAGAWYVEELARICGVSLVADSKYFGLTARAVLHGKDVRLLIPTTYMNLSGKAVGALANFFRITPEEILVAHDELDMPPGVAKFKLGGGHGGHNGLKDIIAKLANDKNFYRLRIGIGHPGDKNKVSGYVLGKAPAKEQELINAAVDEAVRSTEILFKEDMVKAMTRLHSFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_EMENI
Sequence: MAVTIVLGSQWGDEGKGKITDMLSQEATLCCRAAGGHNAGHTIVHGNVTYDFHILPSGLVSDKCINLIGAGTVVHVPSFFKELAALEAKGLKGAAARAFISDRAHVCFDLHSVVDGLEEKGLGGRKVGTTGKGIGPCYSDKASRRGVRVGEILDEEVFERKLRTLHAGYTARFGQLDYDVEEEIARFKEYRKLLVPHIVDQLAFFNKHKDSSNTLVEGANALLLDLDHGTYPFVTSSSTGLGGAVQALHLNPTSIKSIIGVVKAYTTRVGSGPFPSEQLNEAGEKLQKVGREFGVTTGRKRRCGWFDLVLLRYSQSINHYTALNLTKLDILDDFDEIKVAVAYTLPDGTRLENTIPADAEVLNKVDVEYVTLPGWKSNTMGVKKYEDLPENARKYIEYIERELGGVPVKWIGTGPARDDMICRE
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_SUIGR
Sequence: MASIAVTTTTTTTTAEFVTSPRTSIVPEQPNTLHDVIAQAVDSYPLHELGFITSSAHDSSIQTKTFSAFNQYVRNLARAMLEWGKPTGSVVVVYLTEHEDNMTAVWACLLAGFVPCLQPALSAQQAHKEGHVAHIKNLFGSATWLTSELGAEQINSISGLEVHLLSELKSSAEKFTVAADWVAYEAKPDDEAILFLTSGSTGFSKAVVHTHRTILAACRAKGQSYGLTSESQVLNWVGFDHVAGSLEMHITPLLYGASQLHVHASAILADPLRLLRLIDEKSIELAFAPNFLLSKLTRDLEKRTDLFGSFDLSSIKRINSGGEAVVSKTAQAFAATMKQLSKNPSAVSFVISAGFGMTETCAGCIYDPVDVLKNKPAHEFLDLGRPINGCEMRIVDPEDGATLRPDGESGELQVRGPMVFVRYYNNAEATSSSFVEGGWYRTGDVGIIENGVMRLSGRIKDTVIVHGVSYGIPELETYLQTVEGVTHSFLAAAPYRAPGQETEGFIIFYSPTFDLNGADASTKLFATHRALRDICVKMITLPPQFVVPIPVNQMEKTTLGKLSRARLISLFKQGQLAQHIARSEELLSEARGATFVAPSTETEKALAKIYAGIFNLAESEMSASDNFFELGGTSIDVIRLKREGEAHFGLPEIPTIQILKHPVVSSLANYVNALLSKDSQTEEYDPIVPLQLTGNKTPIFFVHPGVGEVLIFVNLAKYFQNERPFYALRARGFEPGHPFFTSMDEMVSCYAAAVKRTQATGPYAIAGYSYGGVVAFEVAKRLEAMGDEVKFTGLINIPPHIADRMHEIDWTGGMLNLSYFLGLVSKHDANDLAPALRPMTRNEQLEVVWKLSPPERLVELQLTPGKLDHWVDIAGSLIECGKDYNPSGSVSAVDVFYAIPLRGSKADWLNNQLKPWSGFSRGDASYTDVPGQHYTLMDFDHVPQFQKIFRGRLEARGL
What is the function of this protein?
An L-tyrosine:2-oxoglutarate aminotransferase and atromentin synthetase greA catalyze consecutive steps to turn over L-tyrosine into atromentin, which represents the generic precursor molecule for the entire terphenylquinone and pulvinic acid family of pigments, which are widely distributed secondary metabolites in homobasidiomycetes.  The first step catalyzed by the aminotransferase converts L-tyrosine in to 4-hydroxyphenylpyruvate (4-HPP).  Adenylation of two 4-HPP monomers by the greA adenylation (A) domain, covalent tethering of the monomers as a thioester and oxoester onto the greA thiolation (T) and thioesterase (TE) domains, respectively, and symmetric C-C-bond formation between two monomers catalyzed by the greA TE domain leads to atromentin.
What are the official names of this protein?
Atromentin synthetase greA, Nonribosomal peptide synthase-like enzyme greA, NRPS-like.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: YQGF_OPITP
Sequence: MRCLGIDYGTRRIGLAYGDELGVATPLPALVEADPAKRWQSLLATARQRRVTDLVVGHPLNMDDTAGPKAKEAEAVAARLRTELAGVDVHLVDERLTSYEAEATISKTQRRAVRASGVIDSRAATLILQDFLDQRFPPPLPHPAE
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2283_MYCTU
Sequence: MLEKCPHASVDCGASKIGITDNDPATATNRRLASTIRKPPIEHAAGPLGSTSRAGHRSYGGVAS
What are the official names of this protein?
Uncharacterized protein Rv2283.
Protein: RL1_PARDP
Sequence: MAKLSKKQVSARAAFAGKSNLAVEEAVKLVKENASAKFDETVEIAMNLGVDPRHADQMVRGVVTLPNGTGKDVRVAVFARGPKADEAKAAGAEIVGAEDLMETIQSGKIEFDRCIATPDMMPLVGRLGKILGPRNLMPNPKVGTVTMDVKAAVEAAKGGEVQFKAEKAGVVHAGVGKASFEIEKLAENIRAFVDAVNRAKPSGAKGTYVKKVSISSTMGPGVSLDLGSTAAAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PHLB3_HUMAN
Sequence: MGTRSSPEEGTPPPLVPECDVEVQPQGHPEESREQEASEVLAEPSSRGGAEQQAEEEEVGEGSSTESSRDAPEATPPIAMAATPPASTSSREGVRGAARRLQGQQLEALTRVALMEQRVKELQRQRKELRIEMEVEVALLRGELAGERVAARREEEQLRELLEQQAASEQRGRQQREQEQRRLSQERDRLEGLRQRLRKAQGQLDSQPEDQRERLLQGVQEMREQLDVAQRAYEDLEFQQLERESRQEEEDRDSPGPQVPDPKVQELQASMAQHRRGALQHRIRVLEEQLKSLGEQMAAESRGLSRKKEEALQALSQERSRLLELNCLQGTPGGDFSEPNPALTKLLFTQKTDRQLLVLQDAVAHSAATPTSSCLFSVHSSLQGSIGLQRTGSLPRKRGERGSQRGSPRPLSFHCTESLEASALPPAVGDSGRYPLYQLLNCGRGNSCGAIHPDIAHMERLLQQAMAERERLLKAREGTRRGTEGSSGPAVPAITAPPTPPHPPGPRILDLRQHLEGWGHNPENCPHVQVSGCCCRGPLVKMGGRIKTWRKRWFCFDRQARRLAYYADKEETKLKGVIYFQAIEEVYYDHLRCAFKSPNPRLTFCVKTYERLFYMVAPSPEAMRIWMDVIVTAADENHAP
What are the official names of this protein?
Pleckstrin homology-like domain family B member 3.
Protein: TPIS_SHESH
Sequence: MALRRPMVAGNWKMNGSAQLALELFNKFATKLQDDSAEVVLCPPSIYLESVRQQLDANKDALNGCLVRMGAQNLSQHDFGAYTGEVSGQMLKDSGCRYVIIGHSERRRMYGETSDIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDVVIEKNGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPYIGENIRILYGGSVTPSNAADLFAQPDVDGGLIGGVSLNSTEFLSLCSIAMSA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG125_MONPV
Sequence: MNNTIINSLIGGDDFIKRSNVFAVDSQIPTLYMPQYISLSGVMTNDGPDNQAIASFEIRDQYITALNHLVLSLELPEVKGMGRFGYVPYVGYKCINHVSVSSCNGVIWEIEGEELYNNCINNTIALKHSGYSSELNDISIGLTPNDTIKEPSTVYVYIKTPFDVEDTFSSLKLSDSKITVTVTFNPVSDIVIRDSSFDFETFNKEFVYVPELSFIGYMVKNVQIKPSFIEKPRRVIGQINQPTATVTEVHAATSLSVYTKPYYGNTDNKFISYPGYSQDEKDYIDAYVSRLLDDLVIVSDGPPTGYPESAEIVEVPEDGVVSIQDADVYVKIDNVPDNMSVYLHTNLLMFGTRKNSFIYNISKKFSAITGTYSDATKRTVFAHISHTINIIDTSIPVSLWTSQRNVYNGDNRSAESKAKDLFINDPFIKGIDFKNKTDIISRLEVRFGNDVLYSENGPISRIYNELLTKSNNGTRTLTFNFTPKIFFRPTTITANVSRGKDKLSVRVVYSTMDINHPIYYVQKQLVVVCNDLYKVSYDQGVSITKIMGDNN
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from late gene promoters.
What are the official names of this protein?
Scaffold protein OPG125, 62 kDa protein, Rifampicin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus protein OPG125 family.
Protein: THIC_STRAW
Sequence: MTNKDARTPASSQTGEALASPQGDQEAGKSIGWHKAYVAGSRPDLRVPVRQVHLTNGESVTLYDTSGPYTDPSVDTDVRRGLAPLRENWIIARGDTEEYAGRPVRPEDDGIKHTSPRGGLRNLDAVFPGRPRQPRRGRDGQAVTQLAYARRGEITPEMEFVAVRENVSAEVVREEIAAGRAVMPVNVNHPEIEPMIIGKRFLVKVNANIGNSAVTSSIEEEVEKMTWATRWGADTVMDLSTGRNIHTTREWVLRNSPVPIGTVPLYQALEKVDGRAEELTWEIYKDTVIEQAEQGVDYMTVHAGVRLPYVPLTANRKTGIVSRGGSIMAAWCLAHHKESFLYENFEELCEILAAYDVTYSLGDGLRPGSIADANDEAQFAELRTLGELNRIAKRFNVQTMIEGPGHVPMHKIKENIDLQQEICDEAPFYTLGPLTTDVAPAYDHITSGIGAAMIAWWGTAMLCYVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPGAQEWDDALSDARFEFRWEDQFNLALDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMKISQDIRREHGGTRTEVEEGMAQKSKEFAAAGNRVYLPLAD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ACPS_STRPQ
Sequence: MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYKRRLSYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISISHSGNYVQASVILEDKK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_PSYIN
Sequence: MAKQSMKAREVKRAKLVVKFAEQRATLKTTINDVNATDEDRWSAMLKLQTLPRDSSPVRKRNRCSVTGRPHGFLRKFGMSRIKVREHMMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: DEF_LEPIC
Sequence: MSVRKILRMGDPILRKISEPVTEDEIQTKEFKKLIRDMFDTMRHAEGVGLAAPQIGILKQIVVVGSEDNERYPGTPDVPERIILNPVITPLTKDTSGFWEGCLSVPGMRGYVERPNQIRMQWMDEKGNQFDETIDGYKAIVYQHECDHLQGILYVDRLKDTKLFGFNETLDSSHNVLD
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: CYB_PTEGY
Sequence: MTNIRKTHPLLKIVNDSLVDLPVPSSVSSWWNFGSLLAACLAVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWILRYLHANGASMFFICLYIHVGRGLYYGSYMYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIIAALVVVHLLFLHETGSSNPTGIPSDPDMVPFHPYHTIKDILGILMMLTALSMLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAVIPLLHTSKQRSMMFRPLSQCMFWLLVADLLTLTWIGGQPVEHPYIIIGQMASILYFTIILLLMPLASMMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MLTF_ECO57
Sequence: MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGELRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNADLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVVVNDLQTLKETKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELAVALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVDTRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLTKNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHMQDARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLFSRKGSEEKQN
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: FTHS_LAWIP
Sequence: MSLSPLNYADWEIAQAAEKHMKTVYDLGKDLGLDHKEIFPYGHYMGKVDYKSVLSRLEQSSDGKYIDVTAITPTPLGEGKSTTTIGLVQGLAKRGKRSSAAIRQPSGGPTMGVKGSAAGGGLSQCIPLTQYSLGFTGDINAVMNAHNLSMVALTSRMQHERNYSDEKLYALSNMKRLDIDPTNIPMGWVMDFCCQSLRNIIIGIDGVSGKSDGYMMRSHFDIAVSSEVMAILAIAKDLKDFRQRISKIIVAYDKQGKAITTADLEVDGAMTAWMVEAINPNLIQSIEGQPIFVHAGPFANIAIGQSSVIADRLGLKLSEYHVTESGFGVDIGYEKFWNLKCHYSGLTPDAAVIVTTVRALKSHGGAPIPIPGRPLPKEYTEENVGYVEVGSANLIHHINTVKKSGVPPVVCINAFTTDTPSEIAKIRQLCELVGARVAVSKHWEYGGDGALELADAVIDACNEEKNFLPLYDWSLPLKERIEKIAFEVYGAEGVEFSEEAIYKLNKLQADNNSSDLGVCMVKTHLSLSDDPKQKGVPDHWKLHVRDIMFFGGAGFVVPIAGSITLMPGTGSNPSFRRIDVDTDTGKVKGIF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: KAP0_MESAU
Sequence: SLRECELYVQKTDSREDEISPPPPNPVVKRGAISAEVYTEEDAASYVRNVLFSHLDDNERILMGSTLRMYEEFLSKVSILESLDKLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRVLGPCSDILKR
What is the function of this protein?
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
What are the official names of this protein?
cAMP-dependent protein kinase type I-alpha regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: MSRB_BURTA
Sequence: MSGDRDDKRYPYPKDDAELRRRLTPMQYEVTQHAATERPFTGEYTDTEDAGIYHCVVCGTALFESGAKYHSGCGWPSYFKPIDAEVIDEKMDYTHGMTRVEVRCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKPEWK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: RL37A_SULTO
Sequence: MGKVTGIAGRFGARYGSSVRKKWKEIMEKRYQDHQCPVCKTTGKVVRIASGVWYCKKCGAKWAGLAYTPY
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
Protein: SERC_PORG3
Sequence: MKKHNFTAGPCILNDLVLKDAASACLNFAGTGLSVLEVSHRDKEFDAVMLEARNLFKELLDVPEGYEVLFLGGGASLQFYQVPLNLLKKKAAFINTGTWATNAIKQAKIMTQVYGGEVEVLASSEDKNFSYIPKDFVIPEDVDYFHFTTNNTIYGTEIRKDFDTKTRLVADMSSDIFSRPIDVSKYDLIYGGAQKNIGPAGATFVLVKTDVLGQVDRPLPDMLNYQIHIKKDSMFNTPPVFPVYVALQTMKWYKELGGVKVLEKMNLDKAALIYDAIDSSKIFRGTVNPEDRSIMNACFVMKDEYKELEKEFATFAASRGMVGIKGHRSVGGFRASLYNALPIESVQSLVSVMKEFEAKH
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDUB2_CHLTR
Sequence: MEPIHNPPPQTCSYSRPSTTYTSFKDASCGTKVTRIIIALFLIVISCGLILCAYTFRDLLDADYSAQEGPQQATKLLQQLDKVLTGPPLPIWDNEHLFQFSCLMQNKHRRVLPIDICNPLTKFNFLEYICNCLMTKQSVNVNETDMCELFCPPTCTPENYRRLLCTSSVFPFVMWHDPSADTQEAMLTKMDQTMSSGRVGNSHWVLVIVDIEHRCVTFFDSFYDYIASPQQMREQLEGLAASLGAIYPKEGGADSDQEELLSPFQVRIGSTVKVQSPGEFTCGAWCCQFLAWYLENPDFDLEEKVPTNPSERRALLADFISTTEQAMSRYSSLSWPTTD
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protease possesses deubiquitinating and deneddylating activities.
What are the official names of this protein?
Deubiquitinase and deneddylase Dub2, ChlaDub2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Secreted. Host cell. Membrane; Single-pass membrane protein. Note=Secreted, and delivered into the host cell.
Protein: HLOA_HALAU
Sequence: WLNALLHHGLNCAKGVLA
What is the function of this protein?
Antimicrobial activity against S. aureus and P. aeruginosa, possibly by attacking the bacterial cell membrane.
What are the official names of this protein?
Halocidin subunit A.
What are the subcellular locations of this protein?
Secreted.
Protein: ENDA_METJA
Sequence: MVRDKMGKKITGLLDGDRVIVFDKNGISKLSARHYGNVEGNFLSLSLVEALYLINLGWLEVKYKDNKPLSFEELYEYARNVEERLCLKYLVYKDLRTRGYIVKTGLKYGADFRLYERGANIDKEHSVYLVKVFPEDSSFLLSELTGFVRVAHSVRKKLLIAIVDADGDIVYYNMTYVKP
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
Protein: EX7S_THEMA
Sequence: MNFEEMMKELEEIVNRLENEDLPLEESIKLFERGVELYRKCKEILQQNRLKIIDVMKELEGEIDASGRDQENELR
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.