PharMolix/UniProtQA huggingface dataset:
Protein: PGM2_MOUSE
Sequence: MAAATPTETPAPEGSGLGMDARLDQETAQWLRWDQNPLTSESVKQLIAGGNKEELRKCFGARMEFGTAGLRAPMGAGISRMNDLTIIQTTQGFCRYLEKQFSDLKQRGVVISFDARAHPASGGSSRRFARLAATAFITQGVPVYLFSDITPTPFVPYTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDRGISQAIEENLEPWPQAWEESLVDSSPLLHNPSASIGNDYFEDLKKYCFHRTVNKESKVKFVHTSVHGVGHEFVQLAFKAFDLAPPEAVPQQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKIKAKIVLANDPDADRLAVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNQDQSNLKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAQQLGDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVICAELASFLATKNLSLSQQLNAIYVEYGYHITTASYFICHDQGTIQNLFGNLRNYDGKNNYPKMCGKFEISAIRDLTTGYDDSQPDKKAVLPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYAELCAPPGNSDPEHLKKELDELVGAIEEHFFQPQKYNLQPKAE
What is the function of this protein?
Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses.  Catalyzes the interconversion of glucose-1-phosphate into glucose-6-phosphate but with a lower catalytic efficiency.  In vitro, has also a low glucose 1,6-bisphosphate synthase activity which is most probably not physiologically relevant.
What are the official names of this protein?
Phosphopentomutase, Glucose phosphomutase 2, Phosphodeoxyribomutase, Phosphoglucomutase-1, Phosphoglucomutase-2, PGM 2.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: NELL2_XENTR
Sequence: MEFILGIFCVIFCLRAGAGFGVDPSLQIDIFEDFQLGEATPGVQQVQGFHNRSKAFLFQDTSRSIKASAETAERIFTKLRNKHEFTILVTLKQAMLNSGVILSIHHADHRYLELESSGHRNEVRLHYRSGSHRSQTEVFPYILADDKWHRFSIAISASHLVLHIDCNKIYERIVEKTFMDVPPGTALWVGQRNNVHGYFKGIMQDLQIVVMPQGFISQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERSCTVKGNIYRELESWMDGCKKCTCTNGTAQCETLTCSVPNCLSGFAPAYVPGKCCKECQPVCMYQGQMYFEGEQEAVQSSSGACVLFQCKSNTMQRIESPECLPLNCPQSQHITLRSGCCKVCKGHDFCSEGHNCVEYSICKNLNDKAVCICRDGFRALREDSAYCEDIDECTEGRHYCRENTVCVNTPGSFMCVCQTGYLKIDDYSCTEHNECATNQHSCDENAVCYNTVGGHNCVCQPGYTGNGTVCKAFCTDGCRNGGTCIAPNICACPQGFTGPSCEADIDECTEGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSLSGESCEDIDECATGRHSCSNDTVCFNLDGGFDCRCPHGKNCSGDCTHEGKIKHNGQIWVLENDRCSVCSCQVGLVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQSGELTYKSGDTWVQNCQQCRCLQGEVDCWPLPCPEIDCEFSVVPESECCPRCISDPCQADIIRNDITKTCVDETNVVRFTGSSWIKHGTECTLCQCKNGHMCCSVDPQCLQEL
What are the official names of this protein?
Protein kinase C-binding protein NELL2, NEL-like protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: PELO_CHICK
Sequence: MKLVRKDLEKDNAGQVTLIPEEPEDMWHTYNLLQVGDSLRASTIRKVQTESSTGSVGSNRIRTTLTLCVEAIDFDSQACQLRVKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWNADVAAVVMQEGLAHVCLVTPSMTLTRAKVEVNIPRKRKGNCSQHDRALERFYEQVVQAIQRHINFEVVKCVLVASPGFVREQFCDYMFQQAVKTDNKLLLENRSKFLQVHSSSGHKYVLKEALCDPAVTSRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKHVEKANEAMAIDTLLISDELFRHQDVATRARYVKLVDSVRENMGTVRIFSSLHVSGEQLGQLTGVAAILRFPVAELSDQEDESSSEED
What is the function of this protein?
Cotranslational quality control factor involved in the No-Go Decay (NGD) pathway.  Required for 48S complex formation from 80S ribosomes and dissociation of vacant 80S ribosomes.  Recognizes stalled ribosomes and promotes dissociation of elongation complexes assembled on non-stop mRNAs; this triggers endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and to degrade damaged mRNAs as part of the No-Go Decay (NGD) pathway.  Upon mitochondrial damage is recruited to the ribosome/mRNA-ribonucleoprotein complex associated to mitochondrial outer membrane thereby enabling the recruitment of autophagy receptors and induction of mitophagy.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: G6PI_THET8
Sequence: MLRLDTRFLPGFPEALSRHGPLLEEARRRLLAKRGEPGSMLGWMDLPEDTETLREVRRYREANPWVEDFVLIGIGGSALGPKALEAAFNESGVRFHYLDHVEPEPILRLLRTLDPRKTLVNAVSKSGSTAETLAGLAVFLKWLKAHLGEDWRRHLVVTTDPKEGPLRAFAEREGLKAFAIPKEVGGRFSALSPVGLLPLAFAGADLDALLMGARKANETALAPLEESLPLKTALLLHLHRHLPVHVFMVYSERLSHLPSWFVQLHDESLGKVDRQGQRVGTTAVPALGPKDQHAQVQLFREGPLDKLLALVIPEAPLEDVEIPEVEGLEAASYLFGKTLFQLLKAEAEATYEALAEAGQRVYALFLPEVSPYAVGWLMQHLMWQTAFLGELWEVNAFDQPGVELGKVLTRKRLAG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_CAEEL
Sequence: MAARPLVTVYDEKYEATQSQIRLPAVFRTPIRPDLVSFIADQVRRNRRQAHAVNTKAGKQHSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGHMFAPLKVFRRWHRNVNIAQKRYAVSSAIAASGIPALLQARGHVIDQVAEVPLVVSDKVESFRKTKEAVVFLRRSHLWADIEKVYNSKRNRAGKGKLRNRQHKQKLGPVVIYGQDAECARAFRNIPGVDVMNVERLNLLKLAPGGHLGRLIIWTESAFKKLDTIYGTTVANSSQLKKGWSVPLPIMANSDFSRIIRSEEVVKAIRAPKKNPVLPKVHRNPLKKRTLLYKLNPYASILRKASKANVKK
What are the official names of this protein?
60S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: COBQ_PHOLL
Sequence: MGLSLMLQGTASDVGKSVLVAGLCRIFVQDGYRCAPFKSQNMALNSGITINGEEMGRAQIFQAEAAGIEPDVRMNPVLLKPTSERKAQVVLMGKVACSMNAVEYHQYKPSLQQQICEVFHSLASEYDVIVLEGAGSPAEINLRDRDIVNMGMAEMVDAPVLLVADIDRGGVFAAIYGTLALLRPAEKARVKGVIINKFRGDISLLQPGIEQIEALTGVPVLGVMPWLDIDLEDEDGVALQTGKYDGATEKALDITVIRLPHIANFTDFNALAVQPDVRLRYVTQPSALQPSDLIILPGSKNTLGDLQWLRQNGLADALLTAHQAGVPVIGICGGYQMLGKRIIDGVESGIEQMDGLGLLDMETRFAHEKVTTRVNGNCLLALPGLLSECVEQPIRGYEIHMGSSLLGADATPFIDITERNGQSGGWCDGAVNREGSVMGSYIHGLFDSANFTRALLNALRQRKGLAAYQGEILDYTHYKQTQFDLLAKAMREHLDIERIYQCMKTHRQGSVP
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: MED9_BOVIN
Sequence: MASVGVAAGRQAEDTLPPPAEPPLPEMKPLPQPQPPPSVSAQQPQPAPKPPSPAGVKAEENCSFLPLVHSIIKCMDKDSPDIHQDLNTLKAKFQEMRKVVSTMPGIHLSPEQQQQQLQRLREQVRTKNELLQKYKSLCMFEIPKE
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 9, Mediator complex subunit 9.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 9 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS6_STRPB
Sequence: MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWEKRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: STHA_YERP3
Sequence: MQQHFHFDAIVIGSGPGGEGAAMGLVKQGARVAVIERYNNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDNARTIKSSFADILNHADRVINQQTRMRQGFYDRNHCHMFSGDASFIDANTVNVRYADGTSDTLQADNIVIATGSRPYRPVNVDFNHERIYDSDTILQLSHEPQHVIIYGAGVIGCEYASIFRGLSVKVDLINTRDRLLAFLDQEMSDALSYHFWNNGVVIRHNEEFEQIEGTTDGVIVHLKSGKKVKADCLLYANGRTGNTSGLGLENIGLEADSRGLLKVNSMYQTALSHVYAVGDVIGYPSLASAAYDQGRIAAQAMIKGEANVHLIEDIPTGIYTIPEISSVGKTEQELTAMKVPYEVGRAQFKHLARAQIVGMDTGSLKILFHRETKQILGIHCFGERAAEIIHIGQAIMEQKGEGNTLEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVSE_HALH5
Sequence: MRIQFGYVAMSMELANASPSKTMTATQFEKIEDHEAGLRKLERIAKTNLHNCLRLLKHNLAYQISFFRLSSKLVPLVNHPLTEGWKYELAIAEELQAVGEFASEHQMRIDFHPDHFVVLNSEAKEITRRSLQTLLYHYKLLKGMEIDPRHRCVLHVGGKKKGVEAGLEQFIENTASIPKSLLSMIMLENDDKSYTIDDVLYLGEKLAIPVVLDIHHHDVLHRSKSLQETWQRIVATWEDSPLPVKIHLSSPLSGEDDPRHHDYINADRFIAFLHEIGADAVDHLHVMIEAKKKDLALFQLMKDLAEYDEITVVSKSAVEFNP
What is the function of this protein?
Component in a DNA repair pathway.  Removal of UV LIGHT damaged nucleotides.  Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion (By similarity).
What are the official names of this protein?
UV DNA damage endonuclease, UV-endonuclease, UVED.
What is the protein family that this protein belongs to?
Belongs to the uve1/UvsE family.
Protein: NDUS3_CANMA
Sequence: MISRTLLKRTVPASRLLRSFTTSNVRLSAHEEDLVNVNNLPRPKPTENYVPLINPTEKYKVQIEELHKFGTYIMSCLPKYIQQFSVWKDELTIYVAPSAIRPVMSYLKNHTSCQFKAVMDITAADYPSRTNRFDVVYNLLSDRHNSRIRVKTYANETSPVPSVTPLFNGANWYERETYDLFGVFFVGHPDLRRIMTDYGFEGHPLRKDFPTTGYTEVRYDEEKKRVIYEPLELTQAWRNFTVGSSVWEPVGEGKDFTPESFKLPTPQPEPEQEEKK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).  Essential for N-alkane assimilation.
What are the official names of this protein?
Probable NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial, Alkane-inducible protein 1, CI-31kD, Complex I-30kD.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: RUVA_STAAC
Sequence: MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIHTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGIGPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAMLALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SYD_BAUCH
Sequence: MRTIYCGQLNKSHLGQEVILCGWVYRYRNLGRLIFIELSDREGRVQVVFDLTHPSIFSNAAKLRNDFCIQLHGIVRTRLDKQINYNITTGEIEVLATNLTILNSSQPLPLDINFHNNEEQRLKFRYLDLRNPEMAQRLKLRAKITSLVRHFMEKKGFLDIETPMLTKTTPEGARDYLVPSRVHKGQFYALPQSPQLFKQLLMISGFDRYYQIVKCFRDEDLRADRQPEFTQIDVEASFINAEQICKIMEDLVRHLWREIQEVELENFQYMSYTAAMYRFGSDKPDLRNPIEIVDVVDLVKNTTCTILADIAKDIKNRVVALRVPNGAKLSLNDIKKYEKYIQTYGIKFIIWMKVYQGKDGVKTTQSSITKYLLPEDIMSIIERTGACDGDILFFAAGNNNIINNVMGALRIKLGCDLKLNRENSWAPLWIVDFPMFEKDDEGNLHAVHHPFTAPKNIDIPTLLQYPLKAKANAYDMVINGYEVGSGSVRIHCAELQQTIFSILGMTRNEQSSKFGFFIDALKYGAPPHAGFAFGLDRLVMLLTSTENIRDVIAFPKTTTAIDLMTEAPSIGNTIALKELSIEILDKNKI
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_KLEP7
Sequence: MNDSEFHRLADSLWMTIEERLDDWDGDSDIDCEINGGVLTISFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAASQQAGETVKFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: GLYA_ACIB3
Sequence: MFANISISEFDPELAQAIASEDERQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRYYGGCEFVDVIEQMAIDRAKELFGADYANVQPHAGSQANSAVYLALLNPGDTVLGMSLAHGGHLTHGAKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEHKPRMIVAGFSAYSRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTLRGPRSGLILAKANEEIEKKLQSAVFPGNQGGPLMHAIAAKAICFKEAMSDDFKAYQQQVVKNAQAMAEVFIARGYDVVSGGTDNHLFLLSLIKQDVTGKDADAWLGAAHITVNKNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRELAGWIADVIDSKGDEKVIADVKAKVEAVCAKFPVYAK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_METCA
Sequence: MGIKSDRWIRKMAREHGMIEPFEPHQVRHGDCSSVISYGTSSYGYDVRCSNEFKIFTNINSAIVDPKNFDQNSFVDLVSDVCIIPPNSFALARTVEYFRIPRDVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGVAQVLFLGADDVCETSYRDRSGKYQGQTGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RS18_ROSDO
Sequence: MASKPFFRRRKVCPFSGDNAPKIDYKDTRLLQRYISERGKIVPSRITAVSAKKQRELARAIKRARFLALLPYAVK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: DAPE_YERPA
Sequence: MICPVIELAQQLIKRPSLSPSDAGCQEIMIQRLAAIGFTIEPMNFGDTLNFWAWRGEGETLAFAGHTDVVPTGDESHWHSPPFEPTIRDGMLYGRGAADMKGSLAAMIVAAERFVAAHPDHKGRLAFMITSDEEAKATNGTVKVVEALMARHERLDYCLVGEPSSTDRVGDIVKNGRRGSITANLRIHGVQGHVAYPHLADNPVHRAMPALNELVATQWDEGNAFFPATSMQIANLQAGTGSNNVIPGEFYVQFNFRFSTELTDSLIKQRVAALLDRHQLDYTLEWVLSGQPFLTAKGALVDAVVNAVKHYTEITPQLLTTGGTSDGRFIALMGAQVVELGPVNATIHKVNECVSAADLQLLSRMYQKIMEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: Y4469_ORYSJ
Sequence: MGSRGDHGGGGGGRGAARATQLKVLVPSSFRKMRICDELAAQLGVGVGGGGAPRAATARVASPLGKAWDVGVVRDGDGRAFLGRGWAEFAAAHGLGVGWFVVLRHGGGVLAVEAFDTTCCLRVFGAPPAEAGRATDTSRKPQFLTVLLPGIMDKMRIPDKFVRDYITGENLNSNMAIILSPLGKSWRVELDKDQSGVFLGGGWLQFLSFHGISRGDVVIFRYEGNLVFKISVFGPNGRQKDFKAKGISIYQGTGEQQEAPSFSRRKCNNKKKSRFGEDDGNQQEMPCSRKGSGNKGRTSDRETKRMRKTRSVYEIGPRSWIKKEINEYVLERCILSLARTFCESIGLVEESSITLMMIDTTSTQGDQGGSSSSSRSWEVTGRRYKDACYLLGAGWRRFCEDNGVRSGDVCVFTVLDTTLWRVDIERC
What are the official names of this protein?
Putative B3 domain-containing protein Os04g0346900.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAV3_PIG
Sequence: MMAEERTDLEAQIVKDIHFKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPVFAALGQVCSNIKVMLRKEV
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Interacts directly with G-protein alpha subunits and can functionally regulate their activity.  May also regulate voltage-gated potassium channels.  Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress.  Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae.
What are the official names of this protein?
Caveolin-3.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Cell membrane, sarcolemma. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: 3MGH_CLOB1
Sequence: MRLTRDFYAKDARVLAKELLGKVLVREVDGIKLKGKIVETEAYIGAIDKASHAYGGRRTKRTEPLYGKPGIAYVYFIYGKYFCFNIISKTEGEAEGVLIRALEPLENINLISKLRFNKEFEELNNYQRKNITSGPSKLCMAFNINRDNNWEDLCESSSLYVEDVFYNDFEIIETVRVGIDYAEEARDFLWRYYIKDNAFVSVK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: DEHA_RHOPA
Sequence: MPDLADLFPGFGSEWINTSSGRIFARVGGDGPPLLLLHGFPQTHVMWHRVAPKLAERFKVIVADLPGYGWSDMPESDEQHTPYTKRAMAKQLIEAMEQLGHVHFALAGHDRGARVSYRLALDSPGRLSKLAVLDILPTYEYWQRMNRAYALKIYHWSFLAQPAPLPENLLGGDPDFYVKAKLASWTRAGDLSAFDPRAVEHYRIAFADPMRRHVMCEDYRAGAYADFEHDKIDVEAGNKIPVPMLALWGASGIAQSAATPLDVWRKWASDVQGAPIESGHFLPEEAPDQTAEALVRFFSAAP
What is the function of this protein?
Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate.  Has lower activity towards bromoacetate and chloroacetate.
What are the official names of this protein?
Fluoroacetate dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
Protein: MURB_COXBU
Sequence: MDKENFTRLRGELFCDHPLARYTSWRVGGKAERFYRPADLFDLQDFLTQLPSDEPLTWLGLGSNVLIRDGGIKGTVILTLNRLKELSVVNSQLVFREKSGTEDFFSGNGKTIIRAEAGVTCAKLAKFCVSQGLEDGAFFAGIPGTVGGALAMNAGAFGGETWRTVIGVETMNHQGEILKRTPDEFKIHYRQVEGLENQFFIAGYFCFNHGDPDKAKTAINALLKKRNLSQPIGKYSCGSVFRNPPGDYAARLIESAGLKGKSIGNAEVSEKHANFILNKGNASAADIEALIHYVAQHVSQIHGIQLVKEVHIIGRS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_STAAC
Sequence: MTHLFEGVGVALTTPFTNNKVNIEALKTHVNFLLENNAQAIIVNGTTAESPTLTTDEKERILKTVIDLVDKRVPVIAGTGTNDTEKSIQASIQAKALGADAIMLITPYYNKTNQRGLVKHFEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPYIVALKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGTLLSALSVDINPIPIKALTSYLGFGNYELRLPLVSLEDTDTKVLRETYDTFKAGENE
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_SYNAS
Sequence: MEAKATAKYIRISPQKARLVVDLIRGKKVDDAREILNYSRKRSGQIVGKVLKSAFANAVQNPNIDEKILFVKEIFVDQGPSMKRWRARAQGRAASIKKRMSHITVILDEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PROA_POLNA
Sequence: MNALNIADYMQTLGLQAKTASAQVARAPAAIKNRALKNLAALLRQNLGSLQAANQRDLERASAAGLAGPLLDRLKLSAKDLETVALGCEQLAAMPDVIGEIIGMKEQPSGIRVGQMRVPIGVFGMIYESRPNVTIEAASLAIKSGNACILRGGSEAIESNKALAALVRQALEQAGLPADAVQLVGTTDREAVGQLIAMPQYVDVIIPRGGKGLIERISRDAKVPVIKHLDGNCHVYVDDPCDIAMAVKIADNAKTQKYSPCNATEGLLVARGVADAFLPQIAAIYAAKGVEMRCDEAAAHILHAHPAIESIANIVPASEQDWYEEYLAPVISIKVVSGVEEAIAHINRYSSHHTDAILTRDHMHAQQFLREVDSASVMVNASTRFADGFEFGLGAEIGISTDKFHARGPVGIEGLTSLKYVVLGQGEVRT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_BRUC2
Sequence: MNTDDVLAVFREAGAILEGHFILTSGLRSPVFLQKARVFMHADKTEKLCKALAEKIRAADLGPIDYVVGPAIGGLIPSYETSRHLGVPSVWVERENGVFRLRRFDVPKGARVVIVEDIVTTGLSIRETIDCMKDLGIEVVAAACIVDRSAGKADVGTRLISLAAYEVPAYPADKLPPELAAIPAVKPGSRNI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CASQ2_PONAB
Sequence: MKRTHLFIVGVYVLSSCRAEEGLNFPTYDGKDRVVSLSEKNFKQVLKKYDLLCLYYHEPVSSDKVAQKQFQLKEIVLELVAQVLEHKAIGFVMVDAKKEAKLAKKLGFDEEGSLYILKGDRTIEFDGEFAADVLVEFLLDLIEDPVEIISSKLEVQAFERIEDYIKLIGFFKSGDSEYYKAFEEAAEHFQPYIKFFATFDKGVAKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEFVKEHQRPTLRRLRPEEMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPDDFPLLVAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDDEDDDDDNSDEEDNDDSDDDDDDE
What is the function of this protein?
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.  Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits.  Can bind around 60 Ca(2+) ions.  Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction.  Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
What are the official names of this protein?
Calsequestrin-2, Calsequestrin, cardiac muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the calsequestrin family.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum lumen. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells.