PharMolix/UniProtQA huggingface dataset:
Protein: MOAA_VIBCM
Sequence: MERCSVAQQFEDRFQRKFYYLRLSITDVCNFKCTYCLPDGYKPSAGRPASFLTVNEIRRVVSAFAHCGTSKVRITGGEPSLRKDFGEIIHTIAQTPGIQKVATTTNGYRLAKHIGEWREAGLTQLNVSVDSLDPRMFAQITGENRFQQVMSGIDRAFEVGFEQVKVNVVLMKNLNHLELPQFMAWIKTRPIQLRFIELMQTGEMDALFARHHVSGISIRDYLFGNGWLLKARADNDGPAQVFIHPDFQGEIGLIMPYEKDFCRSCNRLRVSALGKLHLCLFGEQGIELRDLLQDDHQENALIERIQTQLQNKAETHFLHDGNSGVTPHLASIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: FAF1_MOUSE
Sequence: MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSDFGGETMPGPTFDPASHPAPASTPSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDSCTVGEIKQILENELQIPVPKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSSSHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTVQEVKRNVYDLTSIPVRHQLWEGWPASATDDSMCLAESGLSYPCHRLTVGRRTSPVQTREQSEEQSTDVHMVSDSDGDDFEDASEFGVDDGEVFGMASSTLRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDLTKDTNRARFLTMCNRHFGSVIAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFSAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGFPWDEFKLLSTFPRRDVTQLDPNKSLLEVNLFPQETLFLQAKE
What is the function of this protein?
Ubiquitin-binding protein (By similarity).  Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (By similarity).  Potentiates but cannot initiate FAS-induced apoptosis (PubMed:8524870).
What are the official names of this protein?
FAS-associated factor 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CO2A1_XENTR
Sequence: MFSFVDSRTLVLFAATQVILLAVVRCQDEEDVLATGSCVQHGQRYSDKDVWKPEPCQICVCDTGNVLCDEIICEDPKDCPNAEIPFGECCPICPTEQSSTSSGQGVLKGQKGEPGDIKDVVGPKGPPGPQGPSGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPVGPPGPPGPPGLGGNFAAQMTGGFDEKAGGAQMGVMQGPMGPMGPRGPPGPTGAPGPQGFQGNPGEPGEPGAGGPMGPRGPPGPAGKPGDDGEAGKPGKSGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGSKGEAGAAGAKGEGGATGEAGSPGPMGPRGLPGERGRPGASGAAGARGNDGLPGPAGPPGPVGPAGAPGFPGAPGSKGEAGPTGARGPEGAQGPRGESGTPGSPGPAGASGNPGTDGIPGAKGSSGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGDPGVAGFKGEHGPKGEIGSAGPQGAPGPAGEEGKRGARGEPGAAGPLGPPGERGAPGNRGFPGQDGLAGPKGAPGERGVPGLGGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGASGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLLGAPGLRGLPGKDGETGAQGPNGPAGPAGERGEQGPPGPSGFQGLPGPPGSPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSSGPQGLQGPRGLPGTPGTDGPKGATGPSGPNGAQGPPGLQGMPGERGAAGISGPKGDRGDTGEKGPEGAPGKDGSRGLTGPIGPPGPSGPNGEKGESGPSGPAGIVGARGAPGDRGETGPPGPAGFAGPPGADGQAGLKGDQGESGQKGDAGAPGPQGPSGAPGPQGPTGVNGPKGARGAQGPPGATGFPGAAGRVGPPGPNGNPGPSGAPGSAGKEGPKGARGDAGPTGRAGDPGLQGPAGVPGEKGESGEDGPSGPDGPPGPQGLSGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGGPGSAGDRGPPGPVGPPGLTGPAGEPGREGNAGSDGPPGRDGATGIKGDRGETGPLGAPGAPGAPGAPGPVGPTGKQGDRGESGPQGPLGPSGPAGARGLPGPQGPRGDKGEAGEAGERGQKGHRGFTGLQGLPGPPGTAGDQGASGPAGPGGPRGPPGPVGPSGKDGSNGLPGPIGPPGPRGRGGETGPAGPPGQPGPPGPPGPPGPGIDMSAFAGLSQPEKGPDPMRYMRADQASSSVPQRDVDVEATLKSLNNQIESIRSPDGTKKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTVDAIKVFCNMETGETCVYPNPSKIPKKNWWSAKGKEKKHIWFGETINGGFQFSYGDDSSAPNTANIQMTFLRLLSTDATQNITYHCKNSIAFMDEASGNLKKAVLLQGSNDVEIRAEGNSRFTYNALEDGCKKHTGKWSKTVIEYRTQKTSRLPIVDIAPMDIGGADQEFGVDIGPVCFL
What is the function of this protein?
Type II collagen is specific for cartilaginous tissues.  It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces (By similarity).
What are the official names of this protein?
Collagen alpha-1(II) chain, Alpha-1 type II collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RECR_YERPE
Sequence: MQTSPLLESLMEALRCLPGVGPKSAQRMAFQLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEHCTICLNPRRQQNGQICVVESPADIHAIEQTGQFGGRYFVLMGHLSPMDGIGPGDIGLDLLEKRLSTEAISEVILATNPTVEGDATANYIGQMCGQYGILASRIAHGVPVGGELEMVDGTTLSHSLAGRNPIKY
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PDXJ_BRUMB
Sequence: MPAKLSVNLNAIAMLRNRRDLPWPSVTGLGRAALAAGAAGLTVHPRPDQRHIRFSDLGDIRALIDDEYPQAEFNIEGFPSEAFLDLVEKHEPEQVTLVPDDPMQATSDHGWDFMSKADFLAPIVARLKGRGMRVSLFADPDSLGYERAKAIGADRVELYTGPYGATHDDPAAAARELDRLEKAARAATALGLAVNAGHDLTVDNLPALVKRIPQLAEVSIGHGLTADALMYGIPVTVSRYITALAG
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXDL1_HELPJ
Sequence: MNYDNYWDEDKPELNITPLVDVMLVLLAILMVTTPTLTYKEEIALPSGSKTARATQDKVIEIRMDKDAKIYIDSQTYEYNSFPDTFNLLSKKYDKDTRVSIRADKRLTYDKVIYLLKTIKEAGFLKVSLITSP
What are the official names of this protein?
Putative biopolymer transport protein ExbD-like 1.
What is the protein family that this protein belongs to?
Belongs to the ExbD/TolR family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: SYM_YERPN
Sequence: MAQVAKKILVTCALPYANGSIHLGHMLEHIQADIWVRFQRMRGNQVHFICADDAHGTPIMLKAQQMGIEPEQMIAEMSQEHQQDFAGFAISYDNYHSTHSDENRELSSLIYGRLKANGYIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKAPEQYGDNCEVCGATYSPTELIDPKSAVSGATPVMRESEHFFFDLPAFSDMLQAWTRSGALQEQVANKMQEWFDSGLQQWDITRDAPYFGFEVPDAPGKYFYVWLDAPIGYMGAFKNLCDKRGDLDFDEFWGKDAKTDLYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKAGTYLKYLDADCLRYYYAAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFAGQLADQLADPVLYKTFTDAATSIADAYNNRESGKAIREIMALADVANRYVDEQAPWVVAKQEGRDADLHAICSMGINLFRVLMTYLKPVLPSLTERTEAFLNTELTWDSIEQPLLGHSITAFKALFNRIDLDKVNEMVASSKEDMAPATRVTGPLADDPIQETISFDDFAKVDMRIALIQQAEFVEGSDKLLKLTLELGGETRQVFSGIRSAYPDPKALEGRMTVMVANLAPRKMRFGVSEGMVMAAGPGGSDIFLLSPDSGAQPGMQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPB2_RICFE
Sequence: MNKAKIFMNGQSQAVRLPKEFRFSVKEVSVIPLGKGIVLQPLPNSWKDVFQEMAEISSDDIFPEGRKDLPPQKRKYFE
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Upon expression in E. coli or S. cerevisiae neutralizes the effect of cognate toxin VapC2, partially inhibits the RNase activity of VapC2.
What are the official names of this protein?
Antitoxin VapB2.
What is the protein family that this protein belongs to?
Belongs to the VapB family.
Protein: NINH_BP933
Sequence: MTFTVKTIPDMLVEAYENQTEVARILNCSRNTVRKYTGDKEGKRHAIVNGVLMVHRGWGKDTDA
What are the official names of this protein?
Protein ninH.
What is the protein family that this protein belongs to?
Belongs to the ninH family.
Protein: PT1L_HUMLU
Sequence: MELSSVSSFSLGTNPFISIPHNNNNNLKVSSYCCKSKSRVINSTNSKHCSPNNNNNNNTSNKTTHLLGLYGQSRCLLKPLSIFSCKDQRGNSIRASAQIEDRPPESGNLSALTNVKDFVSVCWEYVRPYTAKGVIICSSCLFGRELLENPNLFSWPLIFRALLGMLAILGSCFYTAGINQIFDMDIDRINKPDLPLVSGRISVESAWLLTLSPAIIGFILILKLNSGPLLTSLYCLAILSGTIYSVPPFRWKKNPITAFLCILMIHAGLNFSVYYASRAALGLAFVWSPSFSFITAFITFMTLTLASSKDLSDINGDRKFGVETFATKLGAKNITLLGTGLLLLNYVAAISTAIIWPKAFKSNIMLLSHAILAFSLFFQARELDRTNYTPEACKSFYEFIWILFSAEYVVYLFI
What is the function of this protein?
Involved in the biosynthesis of prenylated phenolics natural products which contribute to the bitter taste of beer and display broad biological activities (Probable).  Catalyzes the first prenylation step in the beta-bitter acid pathway (PubMed:25564559).  Uses dimethylallyl diphosphate (DMAPP) as the prenyl donor (PubMed:25564559).
What are the official names of this protein?
2-acylphloroglucinol 4-prenyltransferase, Aromatic prenyltransferase PT1L, Humulus lupulus prenyltransferase-1-like, HlPT1L.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Plastid. Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: CCD47_PONAB
Sequence: MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMETYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTDGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRRDQKKLEKKQMKMKQIKVKAM
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes.  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity).  Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein.  Within the PAT subcomplex, CCDC47 occludes the lateral gate of the SEC61 complex (By similarity).  Involved in the regulation of calcium ion homeostasis in the ER.  Required for proper protein degradation via the ERAD (ER-associated degradation) pathway (By similarity).  Has an essential role in the maintenance of ER organization during embryogenesis (By similarity).
What are the official names of this protein?
PAT complex subunit CCDC47, Coiled-coil domain-containing protein 47.
What is the protein family that this protein belongs to?
Belongs to the CCDC47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Rough endoplasmic reticulum membrane.
Protein: HUTI_PARD8
Sequence: MENSKILIRNAAQIVTCHGDKARRGAEMSDLGVIEDGAVAMSDGVITHVGPTEEVLRNIHAEDYLEIRAENQAVLPGFVDSHTHFIFGGYREEEFSWRLRGDSYMSIMERGGGIVNTMKATRESDFDTLWDRGEERLDELFSMGVTTVEGKSGYGLDLQTELVQLRVMSDLNESHPMDVVSTFLGAHAVPPEFAGRTDDYVDYMIEEVLPAIRAEHTVTFCDVFCEKGVFSLEQSERLLRAARHHRFKLKMHADEIVPFGGAELAASLKCVSADHLLHISDTGIKRLARAGVVATLLPLTAFSLNEPYAPARKMIDAGCAVALASDLNPGSCFSASIPMMIALACIYMKMTPEEAVTALTINGAAAVGRASEIGSISVGKRADVILLKYPSYKFLPYHVGMNLVDTVIKDGELYMM
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BHUA_BRUAB
Sequence: MKFTRTLVLASTSLLATVATSQAQEVKRDTKKQGEVVLKPITIISHGKDNIEATGGTVLTYKDIEKLQPANVSELFSRQSSIAVSGGGGPSKRIHVLGMEQSNLAVSVDGVPQTATSWHHTGSNVIDPAFLKRVEVEAGAAAADSGFGAAAGAIRYETVNALDLLEPGKTFGARIIGSYGTNGRGFSGSTAAYGLKDGFDWLLMLHGTSGHNYKNGDGTEILGTEPAARNILGKAGYEFDGNRIDIGYERSRDKADRLIKMNMGLPGDTEYPLEVARDSVNIKYTRTDATDMWDPEVQFYYNRNDYWRNDYQNRTNGNMILKEDLYGGKLQNTFTIDYGKITAGIDFGKHDYNTDNYGHNDRRYRKFNTQQVGAFTQGRFEFDNGFSLSTGARYDYSRFADWNDEVFSDSGASVNGTLSYKFNEHIEVFAGASRTWLGYVLGDYGYVHARNNAFYTDPTFSPGRARNYKAGVNFGGADWSAGITLFDTRIAGLPNYDSQKLGNDPEEYRSRGFTLNARYIWNYTTIGATFTKAKVTAGDDPVLPNSGSFMPIGDMATLFIDQEIPDYNMKVGATLAWAGRISDEAATAANFYDQPAYTVVNAYAEWNPPAVKNMTLRVGVENLFNENYYERTSFAPSQNRGGIDAVWAPGRTFTFQTAFKF
What is the function of this protein?
Heme transporter.
What are the official names of this protein?
Heme transporter BhuA.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS6_METNO
Sequence: MALYEHVFLARQDVTSQQVESMIDTYKGVIEANGGKVEKTEMWGVKSLAYRIKKNRKAHFTLLNIDAPPAALAEMERQMRISEDILRFLTIRVEALETEPSAMMQKRDRDERKDRERGRRRDEDGFSGDRNEEN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RPN1_CANLF
Sequence: MEVPTARLLLLLLLGAWAPAPESASPEAPLLVNEDVKRTVDLSSHLAKVTAEVVLAHPGGGSTARAASFLLALEPELEARLAHLGVQVKGEDEEENNLEVRETKIKGKSGRFFTVKLPVALDPGAKVSVVVETVYTHVLQPYPTQITQSEKQFVVFEGNHYFYSPYPTKTQTMRVKLASRNVESYTKLGNPTRSEDLLDYGPFRDIPAYSQDTFKVHYENNSPFLTITSMTRVIEVSHWGNIAVEENVDLKHTGAVLKGPFSRYDYQRQPDSGIASIRSFKTILPAAAQDVYYRDEIGNVSTSHLLILDDSVEMEIRPRFPLFGGWKTHYIVGYNLPSYEYLYNLGDQYALKMRFVDHVFDEQVIDSLTVKIILPEGAKNIQVDSPYEISRAPDELHYTYLDTFGRPVIVAYKKNLVEQHIQDIVVHYTFNKVLMLQEPLLVVAAFYILFFTVIIYVRLDFSITKDPAAEARMKVACITEQVLTLVNKRIGLYRHFDETINRYKQSRDVSTLNSGKKSLETEHKALTSEIASLQSRLKTEGSDLCDKVSEMQKLDAQVKELVLKSAVEAERLVAGKLKKDTYIENEKLISGKRQELVTKIDHILDAL
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Ribophorin I, RPN-I, Ribophorin-1.
What is the protein family that this protein belongs to?
Belongs to the OST1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Single- pass type I membrane protein.
Protein: CYB_ARTPH
Sequence: MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTELVQWIWGGFSVYKATLTRFFAFHFLLPFIVAALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLVMLTALATLVLFSPDLLGDPDNYIPANPLITPPHIKPEWYFFFAYAILRSIPNKLGGVLALVMSILILAIVPILHMSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILFLMPMTSMVENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRUB_TREDE
Sequence: MELNKNLIIPFAKQAGLTSFASMSAVKKALSTKKVGHTGTLDLFADGLLVLLTGQLTRLADIISAEKKTYEAWVEFGTETDTLDPEGEPVLTAPLPSYKNLTESIPSFLGKILQRPPEFSAIKINGKRASDRIRSGEKIKIAEREIEIFKIELKGIITDSGLEFTEKDFTNINAELKIRYAHIVVECSKGTYIRSLVRDLARKASSCAYVRALRRTAVGNFKLEDAAGFDLLNNFSAAPENLFLKEKKILDAAAGKKFYKQKEIDFLEIMAKSIIFSPKTAENLKLPYLFLDRKYLNDFYNGKKIKFNWFLNTDEVLENITGLDLENKKTCVFCGDLWIGIIGLNKNCPKYETVIKN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: KDSA_ECOHS
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSRR_ALIFM
Sequence: MQLTNFTDFGLRALIYLGSLPEGELTSITVVTETFDVSRNHMVKIINKLGQEGYVKTIRGKNGGICLGKPADQIIIGDVIRAIEPLQVVNCAPEFCHITPACRLKGALAKAKQAFLDELDKHTIQDMLTDNSELLILLKRI
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: RAN_RAT
Sequence: MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
What is the function of this protein?
GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs.  Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis.  Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way.  Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensures the directionality of the transport.  Interaction with RANBP1 induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins.  RAN (GTP-bound form) triggers microtubule assembly at mitotic chromosomes and is required for normal mitotic spindle assembly and chromosome segregation.  Required for normal progress through mitosis.  The complex with BIRC5/survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.  Acts as a negative regulator of the kinase activity of VRK1 and VRK2.  Enhances AR-mediated transactivation.
What are the official names of this protein?
GTP-binding nuclear protein Ran, GTPase Ran, Ras-like protein TC4, Ras-related nuclear protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
Protein: ZAPD_BURO1
Sequence: MILYEYPFNERIRTLLRLEDLFERFAFFLAQEDPREHHVALTTLFEIAEVTGRADLKSDLMKELERQRQTLAPFRGNPGIEQNALEAVLGEIEQTLANLAQMQGKTGQHLVDNEWLASIRSRAVIPGGTCKFDLPSYYAWQQWPAEQRRQDIAKWMLPMLPLRDAAAIVLRLARESGQASKVMAMQGSYQQMLSGRSYQLMQVRVPPELRVIPEASANKYMLWVRFTMQDGDVRPRAVDIDVPFHLTLCNL
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
Protein: PSBL_BRADI
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TILS_LACJO
Sequence: MTKFTTFFTENNIEIKNKKFLLAASGGPDSVALLKMLVNFLPNPSEQLIVAHLDHCLRDDSFLESQLLQRLTSALKVKLVEKKWPVELHPQAGVEAKAREYRYAFLAKVGRKYQTDYLLTAHHGDDLIENILLKFIRSGDVAEMNSLQIVGNLGSMKLLRPLVKYSKDELLKYDKDHHLDFIEDKTNFEDDTLRNRLRHHVVPLLKKETSHLVKNANHFSESVALLSKCQSDLFDSLPSPINFSKALRGKKEDIARLNTHEAAAFFDYLIYKKWHQRIHFDEIDLNKNVIFNKENFQLLFYQKYYYLINRNELAVIDPKRKLVKLNEKFSFNGKKYLITQDEKSQKLAGYFYGEKAKYLEVGSLPQGSTLKLATGKQTKAKKKFAENGIPLALRPYCLTVWQEENPVYVESVYQNQEYNPNFIRYNVYIYF
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_MYCBP
Sequence: MVCDPNGDDTGRTHATVPVSQLGYEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDVLAGDEAQNG
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO_FLAJ1
Sequence: MPDNTIRSNSEVVLIGAGIMSATLGLILKELQPDIKIEIYERLDVAAAESSDAWNNAGTGHSAFCELNYTPEKADGSIDPKKAISIAESFEISRQFWSYLVQQNKVPSPENFIKSVPHMSFVWGDKNVEYLRKRFEALQSNPIFADMTFSTDFNQLKEWMPLVMEGREADEKLAATHMEIGTDVNFGALTRSMFNYLEKLDGVTLYFNHEVKKLKQREDKSWRIKITDLSTGQKRKAYTKFVFIGAGGGSLPLLEKADVPEGHGYGGFPVSGQWLKCTNPEVIAKHQAKVYGKASVGAPPMSVPHIDTRVIDGEKALLFGPFAGFSTRFLKNGSYLDLPLSIKANNLIPMLSAGFHNIPLTKYLIEQVRQSPKDRMKALREYLPTARSKDWKLEKAGQRVQVIKKGKDGGGVLEFGTEVINTHDGTLAVLLGASPGASTAVAIMVDLISRCFTNQIKTPEWEAKMKEMIPSYGKTLNDKPELLAEMRKHTAEVLKIK
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.