PharMolix/UniProtQA huggingface dataset:
Protein: PSD13_CHICK
Sequence: MKDVPGFLQQSQSAGPGQAAVWHRLEELYNKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPTVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEEVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCIDVKDLPVSEQQERAFTLGLAGLLGEGVYNFGELLMHPVLESLRSTDRQWLIDTLYAFNSGNVETFQALKSAWGQQPDLAANEALLLQKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKVTVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVRSMEMLVEHQAHDILT
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 13, 26S proteasome regulatory subunit RPN9, 26S proteasome regulatory subunit S11, 26S proteasome regulatory subunit p40.5.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S11 family.
Protein: RL36_THISH
Sequence: MKVRASVKTICRNCKVIRRNGVVRVICKDPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ENGB_BUCAI
Sequence: MNSLDYNKTNFLKSYSKITDIDIQNGIEIAFIGYSNTGKSSAINALTNQKKLARFSKTPGRTQLINFFEVVSGFRIVDLPGYGYSQAPLLVRSKWQKKVYDYLEKREQIKLFVLLMDIRYPLKKLDQKIISIAVQKKISILVLLTKCDKIKINHQKNQADMVFKKLNVLLDSFEIILFSSYKKIGIEKLKLSLNSSYKKHFILNR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: UPP_XANAC
Sequence: MKIVEVRHPLVQHKIGLLRDAALSTKGFRELVTELGTLLAYEATANLDTESHTQPGWAGPVTVQRIAGAKITLVPILRAGLGMLPGVLALIPAARVSVVGLQRDEETLQPVPYFERLTGRLEERDALILDPMLATGGTLIATIDMLKRAGARRIKGIFLVAAPEGLKALEAAHPDVEVYTAAIDDHLNDKGYILPGLGDAGDRIFGTRLE
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SYS_ACIB5
Sequence: MIDPKLLRNNIEVVNAGLAKRGVQLDVQEWASLETRRKDLQSKTEKLQAERNAGAKQVGQIKKSGGDASEIMARMQAIGDEIKAAEVALSELQNEIEQKALSIPNLPDESVPAGKDENDNVEISKWGTPRQFDFEIKDHTDLGEWMGGLEFETATKLTGSRFSVLKGPLARLQRALTQFMLDTHTLKNGYTEAYVPYLVNADSLRGTGQLPKFEEDLFKLQGEKEYYLIPTAEVPVTNFVRDEIIDADRLPLKYAAHTPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQIVKPETSMQALEELTAHAEGILQALGLPYRKILLCGGDMGFGATKTYDLEVWVPSQNTYREISSCSNMGDFQARRMKARYRMDQKKTELVHTLNGSGLAVGRTLLAVMENYQREDGSIEIPEVLRPYMGGATFID
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OST4_DROVI
Sequence: MITDVQLAIFSNVLGVFLFLLVVAYHYINANTGKSSIKTK
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the OST4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: GUAA_BACSU
Sequence: MTKLVNEMILVLDFGSQYNQLITRRIREFGVYSELHPHTLTAEEIKKMNPKGIILSGGPNSVYDENSFRCDEKIFELDIPVLGICYGMQLMTHYLGGKVEAASQREYGKANIRIEGTPDLFRDLPNEQVVWMSHGDLVVEVPEGFTVDATSHHCPNSAMSKADKKWYGVQFHPEVRHSEYGNDLLKNFVFGVCECEGEWSMENFIEIEMQKIRETVGDKQVLCALSGGVDSSVVAVLIHKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFNMNVIKVDAKDRFLNKLKGVSDPEQKRKIIGNEFIYVFDDEADKLKGIDYLAQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTELGIPDEIVWRQPFPGPGLGIRVLGEVTEEKLEIVRESDAILREEIANHGLERDIWQYFTVLPDIRSVGVMGDARTYDYTIGIRAVTSIDGMTSDWARIPWDVLEVISTRIVNEVKHINRVVYDITSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: HMDH_MOUSE
Sequence: MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQAKVSLGLDEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLAFLLAVKYIFFEQAETESTLSLKNPITSPVVTSKKAQDNCCRREPLLVRRNQKLSSVEEDPGANQERKVEVIKPLVVEAETTSRATFVLGASVASPPSALGTQEPGIELPIEPRPNEECLQILENAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMTRGPVVRLPRACDSAEVKTWLETPEGFAVIKEAFDSTSRFARLQKLHVTMAGRNLYIRFQSRTGDAMGMNMISKGTEKALLKLQEFFPDMQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA
What is the function of this protein?
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis.
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein.
Protein: NRFA_ECOUT
Sequence: MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPATPVTVEAKNETFAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVRETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGCADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYFDGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHGKNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQSINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHMHAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQIKAEKQDFIKTVIPQWEEQARKNGLLSQ
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LHDAG_HDVM1
Sequence: MSRSESKGKRAGREQILEQWVDGRKKLEELERDLRKIKKKIKKLEEENPWLGNVKGILGKKDKDGEGAPPAKRARTDQMEVDTGPRKRPLRGGFSDKERQDHRRRKALENKRKQLAAGGKNLSKEEEEELKRLTEEDERRERRVAGPSVGGVNPLEGGPRGAPGGGFVPNMQGVPESPFTRTGEGLDVTGNLGFPWDILFPADPPFSPQSCRPQ
What is the function of this protein?
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging or budding.  Packages the HDV ribonucleoprotein in hepatitis B virus empty particles.  Interacts with both HDV genomic RNA and cytoplasmic tail of HBsAg.  May inhibit viral RNA replication (By similarity).
What are the official names of this protein?
Large delta antigen, L-HDAg, p27.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=isoprenylated in the cytoplasm, and translocates in the nucleus possibly after phosphorylation. Translocates after to nuclear speckle, then to the ER membrane where interaction with Hepatitis B virus antigene takes place (By similarity).
Protein: HEPC_ONCMY
Sequence: LQVLTEEVGSIDSPVGEHQQPGGESMRLPEHFRFKRXSHLSLCRWCCNCCHNKGXGFCCKF
What is the function of this protein?
Seems to act as a signaling molecule involved in the maintenance of iron homeostasis.  Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages.  May also have antimicrobial activity (By similarity).
What are the official names of this protein?
Hepcidin.
What is the protein family that this protein belongs to?
Belongs to the hepcidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYS2_MICDP
Sequence: MVYQSRSFQVEVSGLHQNEVTNQNNYPIRSSGSVFITIPFSRFNEELQRINRLGGKIVNIQPLNLQINEN
What is the function of this protein?
Rod linker protein, associated with phycocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome 8.1 kDa linker polypeptide, phycocyanin-associated, rod, L-8.1/R, Rod-capping linker protein.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=This protein occurs in the rod, it is associated with phycocyanin.
Protein: RL30_STRAW
Sequence: MAQLKITQTKSYIGSKQNHRDTLRSLGLKGINTQVVKEDRPEFRGMVHTVRHLVTVEEVD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RPOA_PARD8
Sequence: MAILAFQKPDKVLMLEADNFFGKFEFRPLEPGYGITIGNALRRILLSSLEGFAITSIKIDGVDHEFGTIPGVIEDVTNIILNLKQVRFKHIVDDIENEKVSITVSGSEVFKAGDIGKQLTGFEILNPDLVICRLDPTASFQIELTINKGRGYVPADENRDPNADIHVIAIDSIFTPIRNVKYSIENFRVEQKTDYEKLVLEIATDGSIHPKEALKEAAKILIHHFMLFSDEKIAIETADTEGNEEFDEEVLHMRQLLKSKLADMDLSVRALNCLKAADVETLGELVKFNKNDLLKFRNFGKKSLTELDELLESLNLSFGMDITKYKLDKE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: HIS1_BORPE
Sequence: MNPAAAPLTLALSKGRIFEETMPLLAEAGIEVPENPESSRKLILPTSDPGLRLIIVRASDVPTYVQYGAADLGIAGKDVLIEHAAQQSGRLYQPIDLNIAKCRLCVAVRQDFDYQAAVHQGARLRVATKYVQSAREHFAAKGVHVDIIKLYGSMELAPLVGLADAIVDLVSTGGTLRANGLAAVEDVMPISSRLIVNQAALKTRGARLQPLIDAFRRASERIA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_CLAM3
Sequence: MSARTKARKRALDVLYVADIRGESIPATLAVEQQRAAAEPDRQASWQYAREIAEGFVAHQDEIDELIETYSVNWTLARMPAVDRAILRIGIWEILFNADVPHGVAISESVDLASSLSTDESASFVNGMLARIAATQA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: FLIE_PSEAE
Sequence: MSQGVEFNRLMLEMRSMQMEAMAKAKPVQAPAEVGAPSFSEMLSQAVDKVNETQQASTAMANAFEVGQSGVDLTDVMIASQKASVSFQAMTQVRNKLVQAYQDIMQMPV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: RUVB_MYCUA
Sequence: MSTDPDEREVSPALTVGDGDVDVSLRPRSLREFIGQPRVREQLQLVIQGAKNRGGTPDHILLSGPPGLGKTSLAVIIAAELGSSLRMTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLDVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPAELERVLVRSAGILGIQLGADAGAEIARRSRGTPRIANRLLRRVRDFAEVRADGVITRDVAKAALAVYDVDELGLDRLDRAVLSALTRSFSGGPVGVSTLAVAVGEEASTVEEVCEPFLVRAGMVARTPRGRVATALAWTHLGMTPPAGANQPGLFE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: IBSD_ECOLI
Sequence: MMKLVIILIVLLLVSFAAY
What is the function of this protein?
Toxic component of a type I toxin-antitoxin (TA) system.
What are the official names of this protein?
Small toxic protein IbsD.
What is the protein family that this protein belongs to?
Belongs to the Ibs toxic protein family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATPB_SYNWW
Sequence: MANVTYGEVTQVIGAVVDIRFKPGELPDLMNAITIRSSEQDAGFTAVAEIDVMLEAMQLLGNDVVRCVALQPTDGISRGMKAVNTGAAIKIPVGEGCLGRILNVLGQPVDEAGPVNASDYWEIHRKPPALVEQLPATQQLETGIKVADLICPYAKGGKIGLFGGAGVGKTVIIQELIRNIAYEHGGYSVFTGVGERTREGNDLWGEMTESGVIDKCALIFGQMNEPPGARLRVGLTGMTVAEYFRDFSGLDVLIFIDNIFRFAQAGNEVSALLGRMPSAVGYQPTLATDMGYLQERITSTRKGSITSAQAVYVPADDLTDPAPATTFAHLDATTVLSRAISELGIYPAVDPLDSTSRILDPQVVGDKHYDTARGVQKILQRYKELQDIIAILGMDELSDEDKLIVARARKIQRFLSQPFHVAEQFTGSPGIYVPTSETVESFSQVLAGKHDNLSEDSFYMVGNIDTAVAKAKRLEA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PAGP_SHIBS
Sequence: MNVSKYVAIFSFVFIQLISVGKVFANADEWMTTFRENIAPTWQQPEHYDLYIPAITWHARFAYDKEKTDRYNERPWGVGFGLSRWDEKGNWHGLYAMAFKDSWNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGPVTFQMTYIPGTYNNGNVYFAWMRFQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: YOAW_BACSU
Sequence: MKKMLMLAFTFLLALTIHVGEASAVIVKDEEKVSFTMTENEKWFMKSDDLNSNHWTSHFGYRFTIFDTEGCTINARIMRMTLSGYEITVSEKNFSGDHFDFSATDRVETMPYKTHYLILTKDPDCGDVKVKGLYGFQFDQPEW
What are the official names of this protein?
Uncharacterized protein YoaW.
Protein: CIRBP_CRIGR
Sequence: MASDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRSRGRGFSRGGGDRGYGGGRFESRSGGYGGSRDYYASRSQGGSYGYRSSGGSYRDSYDSYATHNE
What is the function of this protein?
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival.  Acts as a translational activator.  Seems to play an essential role in cold-induced suppression of cell proliferation.  Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.  Acts as a translational repressor.  Promotes assembly of stress granules (SGs), when overexpressed (By similarity).
What are the official names of this protein?
Cold-inducible RNA-binding protein, A18 hnRNP, Glycine-rich RNA-binding protein CIRP.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Translocates from the nucleus to the cytoplasm after exposure to UV radiation. Translocates from the nucleus to the cytoplasm into stress granules upon various cytoplasmic stresses, such as osmotic and heat shocks. Its recruitment into stress granules occurs in the absence of TIAR proteins (By similarity).
Protein: Y682_SHEPC
Sequence: MEYEFRRNSLTGTFLATFSMDHEVLGQWFSEELGPELAKIQQVLDSVTEILAGKRESWQLIGSDLTLEIDREQARVYANVLGFDEEYELEDAMSLYDAESEAYCGLEDFEQALLSWQEFVQKGI
What are the official names of this protein?
UPF0231 protein Sputcn32_0682.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: UBIG_PHOPR
Sequence: MTKQLNVDPAEISKFEDMASRWWDLEGEFKPLHQINPLRLNYVTDHAGGLFGKKILDVGCGGGILAESMAIEGADVTGLDMGKEPLTVARLHALETGAKLDYVLRTAEEQAELHPETYDIVTCMEMLEHVPNPASVIAACAKMVKPNGHVFFSTLNRNAKSYLFAIVGAEQLLKLVPKGTHDHKKFIRPSELIAMIDQTPLQDRHITGLHYNPLTDNYWLGKSVEVNYIVHTVKL
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: IF3_BUCAI
Sequence: MKGGKIVQLTRPNRINSEIRAIKVRLTGVEGDQIGIVNLREALKKSEELGLDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIHIKEIKFRPGTDEGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQKIGVDVLNRVKNDLIELATVEYFPSKIEGRQMIMILAPKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_STAAW
Sequence: MSKQRIYEYAKELNLKSKEIIDELKSMNIEVSNHMQALEDDQIKALDKKFKKEQKNDNKQSTQNNHQKSNNQNQNKGQQKDNKKNQQQNNKGNKGNKKNNRNNKKNNKNNKPQNQPAAPKEIPSKVTYQEGITVGEFADKLNVESSEIIKKLFLLGIVANINQSLNQETIELIADDYGVEVEEEVVINEEDLSIYFEDEKDDPEAIERPAVVTIMGHVDHGKTTLLDSIRHTKVTAGEAGGITQHIGAYQIENDGKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTIEAINHAKEAEVPIIVAVNKIDKPTSNPDRVMQELTEYGLIPEDWGGETIFVPLSALSGDGIDDLLEMIGLVAEVQELKANPKNRAVGTVIEAELDKSRGPSASLLVQNGTLNVGDAIVVGNTYGRIRAMVNDLGQRIKMAGPSTPVEITGINDVPQAGDRFVVFSDEKQARRIGESRHEASIVQQRQESKNVSLDNLFEQMKQGEMKDLNVIIKGDVQGSVEALAASLMKIDVEGVNVRIIHTAVGAINESDVTLANASNGIIIGFNVRPDSGAKRAAEAENVDMRLHRVIYNVIEEIESAMKGLLDPEFEEQVIGQAEVRQTFKVSKVGTIAGCYVTEGKITRNAGVRIIRDGIVQYEGELDTLKRFKDDAKEVAKGYECGITIENYNDLKEGDVIEAFEMVEIKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_LEGPA
Sequence: MKRTFQPSNLKRKRDHGFRLRMSTRAGRLVIKRRRAKGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: NDB2_TITDI
Sequence: MNKKTLLVIFIVTLLIADEVNSFKFGGFLKKMWKSKLAKKLRAKGKQMLKEYANKVLSPEEEAPAAVPAGAPERRRR
What is the function of this protein?
Antimicrobial peptide (By similarity).  May also inhibit angiotensin-converting enzyme (ACE) and potentiate bradykinin (BK) (Probable).
What are the official names of this protein?
Bradykinin-potentiating peptide, BPP, TdBPP.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSGA_ECODH
Sequence: MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSSMSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSAAMFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSIEWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCYILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTVLAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVLTCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTSH
What are the official names of this protein?
Protein TsgA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.