PharMolix/UniProtQA huggingface dataset:
Protein: TRPA_PSEU2
Sequence: MSRLEHRFAQLKTEGRAALVTFITAGDPGYDTSLKVLKGLPAAGADVIELGMPFTDPMADGVAIQLATLRALDAGQTLQKTLQMVSEFRVDDQTTPIVLMGYYNPIHRFGVEAFVAQAKEAGVDGLIIVDLPPEHDAELATPAQASGIDFIRLTTPTTDDARLPRVLERSSGFVYYVSVAGVTGAGSATTEHVTEAIARLRRHTDLPISVGFGIRTPEQAAAIARLADGVVVGSAFVDKIASAESPEHAIDGVLTLCAALAEGVRSARR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RS6_STAA1
Sequence: MRTYEVMYIVRPNIEEDAKKALVERFNGILATEGAEVLEAKDWGKRRLAYEINDFKDGFYNIVRVKSDNNKATDEFQRLAKISDDIIRYMVIREDEDK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: YXDJ_BACSU
Sequence: MNKIMIVEDSEDIRGLLQNYLEKYGYQTVVAADFTAVLDVFLREKPDVVLLDINLPAYDGYYWCRQIRQHSTSPIIFISARSGEMDQVMAIENGGDDYIEKPFSYDIVLAKIKSQIRRAYGEYAAKQGEKVVEYAGVQLFVERFELRFQDEKSELSKKESKLLEVLLERGEKVTSRDRLMEKTWDTDIFIDDNTLNVYITRLRKKLRELNAPVSIEAVRGEGYQLRAQS
What is the function of this protein?
Probable member of the two-component regulatory system YxdK/YxdJ.  Positively regulates the expression of the yxdLMyxeA operon by direct interaction with its promoter region.  Could also indirectly regulate the expression of the dlt operon.
What are the official names of this protein?
Transcriptional regulatory protein YxdJ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_ARCFU
Sequence: MKLRKSLGQHMLVDRRVISRIVGYAELSEDDVVLEVGCGTGNLTSALLRKCSVVGIEKDPLMVKRLRERFSDFIGKGRFRLIQGDALKVDFPYFTKFVANIPYKISSPLTFKLLKTDFRLAVVMYQREFAERLCGEDNRLGVISKTYCKAEILEIVKPSSFNPPPKVESAIVRIVPEPEVFVENRELFEKFVTFAFSMRRKRMGKIVQEFRKRYGVELAVNKNLAEKRPEELGARKFAEIVVGE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_CERS4
Sequence: MAEQQKGLTYADAGVDIDAGNALVERIKPAAKRTARPGTVSGLGGFGALFDLKAAGYQDPVLVAATDGVGTKLRIAIDTGEVDTIGIDLVAMCVNDLVCQGAEPLFFLDYFATGKLEVAQAARIIEGIAEGCAASGCALIGGETAEMPGMYHKGDFDLAGFAVGAMERGADLPQGVAEGDLLLGLGSNGVHSNGYSFVRKVVELSGLGWDAPAPFGGDSLGRALLAPTRLYVKQALAAVRAGGVHALAHITGGGLTENLPRVLPKGLGARIDLSAWELPPVFRWLAETASMAEPELLKTFNCGIGMIVVVAADRADEIAALLAAEGETVTRIGEVIAGEGVSYDGRLL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_SHEDO
Sequence: MAGAKEIKTKIASVKNTQKITSAMEMVAASKMRRAQERMAASRPYAESMRKVIGHVAQGSLEFKHPYLEVREAKRVGYIVVATDRGLCGGLNVNLFKKVTLDVKNWKAQGAEVEFCPIGARSVQFFKSFGGQVSAHASGLGDAPKLADLIGTVRVMLQAYNEGKLDRLYVVFNKFVNTMAQTPVIEQLLPLPKSADDVKTNRWDYIYEPDPKEILETLLVRYVESQVYQGVIENLASEQAARMVAMKAATDNAGDMIDGLQLVYNKARQAAITQELSEIVSGASAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS8_METTH
Sequence: MTLMDPLANALTNIRNNEIRGNVKCRITPASKLIGRVLRTMQKEGYIGEFEYVDDGRAGKFIVELEGNINHCGVIKPRHAVKKDEFEKFEKRYLPAKNFGIIIVSTPEGIMTHKEAKDRGIGGRLLAYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: IROD_ECOL6
Sequence: MLNMQQHPSAIASLRNQLAAGHIANLTDFWREAESLNVPLVTPVEGAEDEREVTFLWRARHPLQGVYLRLNRVTDKEHVEKGMMSALPETDIWTLTLRLPASYCGSYSLLEIPPGTTAETIALSGGRFATLAGKADPLNKMPEINVRGNAKESVLTLDKAPALSEWNGGFHTGQLLTSMRIIAGKSRQVRLYIPDIDISQPLGLVVLPDGETWFDHLGVCAAIDAAINNRRIVPVAVLGIDNINEHERTEILGGRSKLIKDIAGHLLPMIRAEQPQRQWADRSRTVLAGQSLGGISALMGARYAPETFGLVLSHSPSMWWTPERTSRPGLFSETDTSWVSEHLLSAPPQGVRISLCVGSLEGSTVPHVQQLHQRLITAGVESHCAIYTGGHDYAWWRGALIDGIGLLQG
What is the function of this protein?
Catalyzes the hydrolysis of both the apo and Fe3(+)-bound forms of enterobactin (Ent), monoglucosyl-C-Ent (MGE), diglucosyl-C-Ent (DGE) and triglucosyl-C-Ent (TGE).  Shows higher catalytic efficiencies on Fe3(+)-bound forms.  The initial linear trimer products are, in turn, very good substrates for further hydrolytic cleavage by IroD, leading to complete degradation of the trilactone to DHB-Ser and/or Glc-DHB-Ser monomers.  Hydrolyzes MGE and DGE regioselectively.  May be the ferric MGE/DGE esterase responsible for cytoplasmic iron release.
What are the official names of this protein?
Iron(III) salmochelin esterase.
What is the protein family that this protein belongs to?
Belongs to the Fes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLTP8_ARATH
Sequence: MNVLKCLAIISVLGIFFIPRYSESAISCSVVLQDLQPCVSYLTSGSGNPPETCCDGVKSLAAATTTSADKKAACQCIKSVANSVTVKPELAQALASNCGASLPVDASPTVDCTTVG
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).
What are the official names of this protein?
Non-specific lipid-transfer protein 8, LTP 8.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: KDPA_CLAM3
Sequence: MDTLAGILQVASVVLVLVLIHRPLGDLMARMYESRHDSRVERGIYRLIGVDPRSEQTWPAYLRAVLAFSLVGVLVVYGLQRLQAFLPYALGLPAVPEGLSFNTAVSFVTNTNWQSYSPEATMGYTVQLAGLAVQNFVSAAVGIAVAIALVRGFARTRTGTIGNLWVDLIRGSLRLLLPLSLVTAVILIAGGVIQNFAGFQDVATLAGGSQTIPGGPVASQEAIKMLGTNGGGFFNANSAHPFEDPTAWTSAFQVILMLAIPFSLPRTFGKMVGDTRQGTAIVAVMATIFVVSFTALTIFELNGQGTAPMAAGGAMEGKEQRFGIIASTLFGSASTLTSTGAVNSMHDSYTALGGMMPMINMMLGEVAPGGTGSGLYGMLILAVISVFVAGLLVGRTPEYLGKKIGPREIKLASLYILVTPILVLVGTALSFAIPAVRDDVEGTSILNSGLHGLSEVVYAFTSAANNNGSAFAGLTASTPWFNTALGVAMLLGRFLPIVFVLALAGSLAAQDRIPTTSGTLPTHRPQFVGLLIGVTVIVTALTYFPVLALGPLAEGLAS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EX7S_ALIF1
Sequence: MAVKKPENLSFEAAIEELDSVVNQLESGDLPLEDALKKFERGISLARAGQEKLTQAEQRVEILLQADDNAELTPFDGQDD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA_METS5
Sequence: MAFGPAAMGYDRAITIFSPDGSLYQVDYAFEAVKKGWTTLGVKTKNAVVILGEKKKASQLLDVDSIEKVFLLDDHVGCSFAGLASDGRILIDYARNSSLQHRLVYDEPISIDYLTKLISDVKQMYTQHGGVRPFGVALIVGGVDRGVTKLFMTEPSGQFMPYQAVAIGQGGYNATDYLEKNYKEDLSVEETILLALNALKVTLKPGEKLGPGNVEIGFATKEGQFRKMTLEERANYLQKI
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PsmA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_SHESR
Sequence: MAIGLIGRKVGMTRIFTEDGVSIPVTVIEVAGNRVTQVKTLETDGYRALQVTTGTKKANRITKPEAGHFAKSGVEAGRGLWELRLADGEGEGIEVGAELNVGIFADVAKVDVTGQSKGKGFQGGVKRWNFRTQDMTHGNSLSHRSNGSIGQNQTPGRVFKGKKMSGHMGAERVTTQNLDVVRVDVERNLLLVKGAVPGATNGDLIIKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: TAL_STRP6
Sequence: MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIKEICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGIKTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEIIAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOAI_ECOL6
Sequence: MNDQMFVETLIITSSFFAIAAVLVLSVLLIERTG
What are the official names of this protein?
Uncharacterized protein YoaI.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LEUD_XANOP
Sequence: MTPFTQHTGLVAPLDRANVDTDQIIPKQFLKSIKRTGFGPNLFDEWRYLDIGEPGRDNSTRPLNPEFVLNFPRYQGASVLLARENFGCGSSREHAPWALDEYGFRAVIAPSFADIFYNNSFKNGLLPIVLAEAEVDALFEQCLANEGYQLTVDLAAQRVRRPDGVEYSFDIDAFRKHCLLNGLDDIGLTLQEADAIGRFEQDHRARQPWLFGALQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RNH2_ARTS2
Sequence: MSVAPTLDYEHRFLSSGARLLAGIDEVGRGAIAGPVTVGITVVDLSRPVLLDDVRDSKLLKESDRERLEPLVRNWSVASAVGHASAGEIDALGIIAALRTAGTRAWLQILAAGVTPDVVLLDGSHNWLSPETQASLFDDAPAGPGCDAPVHTLVKADMQCLSVAAASILAKVERDRIMRSLHGEYPAFGWDENKGYGTASHKEALRAAGPSPYHRVSWQIL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_SHIFL
Sequence: MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGDVQPSQDLVRVLNLCDKLAQKRGDNFISSELFVLAALESRGTLADILKATGATTANITQAIEQMRGGESVNDQGAEDQRQALKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVAEPSVQDTIAILRGVKERFELLHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSDKERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQELHHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYAHMKELVLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDEALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAVQ
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL13_PIG
Sequence: MALWLTLVIALTCFGGLASPGPVPPHSTALKELIEELVNITQNQKTPLCNGSMVWSVNLTTSMQYCAALESLINISDCSAIQKTQRMLSALCSHKPPSEQVPGKHIRDTKIEVAQFVKDLLKHLRMIFRHG
What is the function of this protein?
Cytokine that plays important roles in allergic inflammation and immune response to parasite infection.  Synergizes with IL2 in regulating interferon-gamma synthesis.  Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells (By similarity).  Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1 (By similarity).  Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF-alpha through a mechanism that partially involves suppression of NF-kappa-B (By similarity).  Functions also on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils.  Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6.  Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13 (By similarity).
What are the official names of this protein?
Interleukin-13, IL-13.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: COAD_HALH5
Sequence: MTSIAVCPGSFDPVTLGHLDIIQRGANVFDEVIVAVLHNRNKVPLFSVEERLELLKKATEHIPNVTIDSFNGLLIDYVKQKQAKAIIRGLRAVSDFEYEMQAASINKKLGPDVETFFMMTSNQYSYLSSSIVKEVAKYEADVSDIVPPVVAEALKAKFSSSPRNK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
Protein: PYRI_ECOUT
Sequence: MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: EIF3E_NEOFI
Sequence: MAANVPPSAETLLSGAAAHPPKTAEEIANQYNLLPKLIPYLDRHLVFPLLEFSSGQDDEKEVVRAKYELLKHTNMTDYVANLWKEINNSDDIPDEFVKKREEVLAKLQQYEEESAKITQLLQDESVVANLRSDKVANLKFLEEQHGVTIEMVNSLYDYGRFQYSCGSYGNAAELLYQFRVLSTDNDKVASATWGKFASEILTTSWEAAMEEVQKVKDSIETRLFNNPLGQLQNRSWLIHWSLFPFFNHDPARDVLTDLFFSPAYINTIQTNCPWILRYLAAAVITNRNRAHKSSSVYQKQLKDLIRVVRQEGYEYNDPITDFVKALYVDFDFEEAQKKLGEAEDVLRSDFFLVSTTDAFVEAARHLISESYCKIHQRIDIKDLSTRLGLNQDEGEKWIVNLIRDTRVDAKIDYKEGTVIMNHPPQSVYQQVIEKTKGAFFRTQVLRFVRLLYPHD
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_BACSU
Sequence: MIYGIGLDITELKRIASMAGRQKRFAERILTRSELDQYYELSEKRKNEFLAGRFAAKEAFSKAFGTGIGRQLSFQDIEIRKDQNGKPYIICTKLSQAAVHVSITHTKEYAAAQVVIERLSS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of fatty acid acyl-carrier-protein ACP.  Also modifies the D-alanyl carrier protein but fails to recognize PCP and AcpK, an acyl carrier protein of secondary metabolism.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1AT4_HORSE
Sequence: EDLQGTAVQERSAKASDEEEAIRTLLLTNVEFNRPFVLSIYDR
What are the official names of this protein?
Alpha-1-antiproteinase 4, Alpha-1-antitrypsin 4, Alpha-1-proteinase inhibitor 4, SPI4.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LDHA_RHINC
Sequence: MSTKEKLISHVSKEEAVGSRNKVTVVGVGMVGMASAISILLKDLCDELALVDVMEDKLKGEVMDLQHGSLFLKTHKIVGDKDYSVTANSRVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVAWKLSGFPRHRVIGSGTNLDSARFRHIMGEKLHLHPSSCHGWIVGEHGDSSVPVWSGVNVAGVSLQTLNPKMGAEGDSENWKAVHKMVVDGAYEVIKLKGYTSWAIGMSVADLVESIVKNLHKVHPVSTLVKGMHGVKDEVFLSVPCVLGNSGLTDVIHMTLKADEEKQLVKSAETLWGVQKELTL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_PSESM
Sequence: MPNITVTSLLAMKHKGEKITMLTCYDATFAHTACQAGVEVLLIGDSLGMVLQGHDSTLPVTTAETAYHVACVKRGNQGALILADLPFMANATLEQTFINSTTLMQAGAHMIKVEGAAWLGESIRLLAERGIPVCAHMGLTPQSVNVLGGYKVQGRLEAQARQMRADAIALEQAGAAMILLECVPSELAEEITHAVKIPVIGIGAGSATDGQVLVLHDMLGLSITGRVPKFVKNFMIGQPDIQSAIQAYVSAVKDVSFPAIEHGFSA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_KLEP3
Sequence: MNMNATILGQAIAFVIFVWFCMKYVWPPLMAAIEKRQKEISDGLASAERAKKDLDLAQANATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIVAQAQAEIDAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RUVB_PSEMY
Sequence: MIEADRLITASPREREEQQDRAIRPLKLADYIGQPGVREQMELFIQAARGRAESLDHTLIFGPPGLGKTTLANIIAQEMGVSIKSTSGPVLERPGDLAALLTNLEAGDVLFVDEIHRLSPIVEEVLYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGMLTNPLRDRFGIVQRLEFYGIDDLATIVTRSAGILGLPIEDQGAYEIARRARGTPRIANRLLRRVRDFAEVRGRGHITREIADQALNLLDVDERGFDHSDRRLLLAMIEKFDGGPVGVDSLAAAISEERHTIEDVLEPYLIQQGYMMRTPRGRVVTRHAYLHFGLNTPKRLGEQPSGDLFAVSDE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: LPOA_YERPG
Sequence: MLSSTFVRSKAGLVPVILAALILAACTGDAPQTPPPVNIQDEASANSDYYLQQLQQSSDDNKADWQLLAIRALLREAKVPQAAEQLSTLPANLSDTQRQEQQLLAAELLIAQKNTPAAADILAKLEATQLSANQKVRYYQAQIAANQDKATLPLIRAFIAQEPLLTDKAHQDNIDGTWQSLSQLTPQELNTMVINADENVLQGWLDLLRVYQDNKQDPKLLKAGIKDWQTRYPQNPAAKNLPTALTQISNFSQASTAKIALLLPLSGPAQVFADAIQQGFTAAQNGSAVTASVPVTPNVTESSPTDTAAVVSDDTPATLPAPVPPPVVTNAQVKIYDTNTQPLAALLAQAQQDGATLVVGPLLKPEVEQLSATPSTLNILALNQPEASNNSPNICYFALSPEDEARDAAHHLWEQQKRMPLLLVPRGALGERIAKAFADEWQKQGGQTVLQQNFGSTTELKQSINSGAGIRLTGTPVSVSNVAAAPASVTIAGLTIPAPPIDAPVVSTSSSGNIDAVYIIATPSELTLIKPMIDMATSSRSKPALFASSRSYQAGAGPDYRLEMEGIQFSDIPLMAGSNPALLQQASAKYANDYSLVRLYAMGIDAWALANHFSEMRQIPGFQVKGVTGDLTASSDCVITRKLPWLQYRQGMVVPLA
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.