PharMolix/UniProtQA huggingface dataset:
Protein: RS5_ECOLI
Sequence: MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKSVEEILGK
What is the function of this protein?
The physical location of this protein suggests it may also play a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp.
What are the official names of this protein?
30S ribosomal protein S5, Small ribosomal subunit protein uS5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: YTH2_RHOER
Sequence: MTEADYADFLVVGGGTCGCVVAARLSEDPSATVMLLESGSGYRSALELPDVLGDPYRLPVGPASEYTWTYPVELTPRRASTIARGRTLGGSGAVNGAYFMRATRADFENWPSAWRYDDVLPYFKKSETDRDFESEFHGTAGPIPVERRAWDQLHPLSGEFHAAALGAGFPDDVDKNAPDSFGVGRVPLNVADHRRISTAIGYLMPALHRPNLRVESGVNVIRIVFSGTRAVGVDVLDDGNVRRIHADHVIVCSGAVATPHILLNSGVGPAEQLAEQGVSVILDRHGVGQNFVDHPEVLLPYHFSTPRAIRSQTPVLETALNLAELEIRPYTASFTDLVPGVPRMDHGVGVVLMAPRSRGSIELASGDPAGAPRIRYNYVASTHDRAANREGMQIAENLLESIAETGLIDRPVVEYTDEWVESRLGTSLHMSGSCVMGAESDPFAVVDDRCRVIGAQGLSIVDTSILPTIPTRGPHATAVMVAERASAILLGDE
What are the official names of this protein?
Uncharacterized GMC-type oxidoreductase in thcA 5'region, ORF2.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: ACSA_BRUA4
Sequence: MSEKLYPVLAEAKRNTLIDNATYLEWYQESVSDPDSFWAKHGRRIDWFKPFTKVKNTDFNGDVSIKWYEDGVTNVSYNCIDRHLKSRGDQVAIIWEGDNPYIDKKITYRELHENVCRLANVLKKHGVKKGDRVTIYLPMIPEAAYAMLACARIGAVHSVVFAGFSPEALAGRIVDCESTFVITADEGVRGGKPVPLKENTDTAIDIAAKQYVMVNKVLTVRRTGGKVSWGPGRDLWYHQEVASVEPTCDPEPMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYASMTHQYVFDYHDGDIYWCTADVGWVTGHSYIVYGPLANGATTLMFEGVPNFPDQGRFWEVVDKHHVNIFYTAPTAIRALMGAGDEFVTRSSRSTLRLLGSVGEPINPEAWEWYYNVVGDQRSPIVDTWWQTETGGILITPLPGATDLKPGSATRPFFGIKPELVDNEGAVIEGAVDGNLCIIDSWPGQMRTLYGDHKRFIEAYFSTYKGKYFTGDGCRRDEDGYYWITGRVDDVLNISGHRLGTAEIESALVSHHSVSEAAVVGYPHPIKGQGIYCYVTLMTGEAVQDEDALRKELTQHVRKEIGPIATPDKIQFSPGLPKTRSGKIMRRILRKIAEDEFGALGDTSTLADPGVVDDLIENRQNKK
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: LT4R1_MOUSE
Sequence: MAANTTSPAAPSSPGGMSLSLLPIVLLSVALAVGLPGNSFVVWSILKRMQKRTVTALLVLNLALADLAVLLTAPFFLHFLARGTWSFREMGCRLCHYVCGISMYASVLLITIMSLDRSLAVARPFMSQKVRTKAFARWVLAGIWVVSFLLAIPVLVYRTVKWNNRTLICAPNYPNKEHKVFHLLFEAITGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHLVNLVEAGRTVAGWDKNSPAGQRLRLARYVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVVKLLEGTGSEVSSTRRGGTLVQTPKDTPACPEPGPTDSFMTSSTIPESSK
What is the function of this protein?
Receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
What are the official names of this protein?
Leukotriene B4 receptor 1, LTB4-R 1, LTB4-R1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PT1_PINTA
Sequence: MSPVSVISLPSDLCLPTSFIDRSGRELIPLHITIPNVAMRRQGKLMTRASMSMNLRTAVSDDAVIRRRGDFHSNLWDDDLIQSLSSPYGEPSYRERAERLIGEVKNSFNSMSNEDGESITPLDDLIQRLWMVDSVERLGIDRHFKKEIKSALDHVYRYWSEKGIGCGRESVVTDLNSTALGLRTLRLHGYDVSADVLNHFKNQSGQFACTLKQTEDQIRTVLNLYRASLIAFPGEKVMDEAESFSAKYLKEALQKIPVSSFSREIGDVLEYGWHTYLPRLEARNYIDVFGQDTENSKSYMKTEKLLELAKLEFNIFHALQKRELEYLVRWWKGSGSPQMTFCRHRHVEYYTLASCIAFEPQHSGFRLGFAKACHIITVLDDMYDTFGTLDELELFTSAIKRWDPSATECLPEYMKGVYMIVYNTVNEMSQEADKAQGRDTLNYCRQAWEEYIDAYMQEAKWIASGEVPTFEEYYENGKVSSGHRVSALQPILTTDIPFPEHVLKEVDIPSQLNDLASAILRLRGDTRCYQADRARGEEASCISCYMKDNPGTTEEDALNHLNAMISDVIKGLNWELLKPNSSVPISAKKHAFDISRAFHCGYKYRDGYSVANIETKSLVKRTVIDPVTL
What is the function of this protein?
Involved in defensive oleoresin formation in conifers in response to insect attack or other injury.  Involved in monoterpene (C10) olefins biosynthesis.  Produces mainly (-)-alpha-pinene (79%) and lesser amounts of (-)-beta-pinene (4. 2%), nearly racemic mixtures of camphene (2. 8% (+)/2. 2% (-)) and limonene (2. 4% (+)/3. 7% (-)), as well as small amounts of (+)-alpha-pinene (3. 3%) and (+)-beta-pinene (2. 4%).
What are the official names of this protein?
(-)-alpha-pinene synthase, chloroplastic, (+)-(3S:5S)-alpha-pinene synthase, Synthase I.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRPD_LEPCP
Sequence: MSIANIDALTRVIDHREIFHDEMLALMRRIMSGEMSPVMIAAFAIGLRVKKETIGEIAAAAQVMREFATPVAVPDKTNLVDLCGTGGDGVHTFNISTASMFVAAAAGARVAKHGGRSVSSSSGSADVLEALGAHINLTPEQVAISLERCGIGFMFAPNHHASMKHAAPVRKELGVRTIFNILGPLTNPALAPNQVMGVFHPDLVGIQVRVLQRLGSSHVLIVHGMNGMDEISLSGETMIGELKAGQISEYVVHPADFGLPVYDTRVLKVANKEESVTCIQRALANEDGPVRDIVLLNAGAALYAADVVTSITDGVRAAREAVASGQALAKLSQYVAVTQSFKTAV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: TYS3_ENCCU
Sequence: MPQDPRHPEHQYLDLVKHILENGARRMDRTGTGTLSVFGATMRFSLEDNTFPLLTTRRVFYRGVVEELLFFLRGETDSKVLEKKGVRIWEKNGAKQFLQSVGIDREEGDLGPIYGFQWRHFGARYETSASSYEGKGVDQIASAIAAIRANPASRRIVVSAWNPTDLGSMALPPCHVLFQFNVTDGKLSCAMYQRSGDMGLGVPFNIASYSLLTILVAHLTGLQPGEFVHFLGDAHVYLDHVDSLRQQVQRPPRAFPKLFVSPKGPRTEPEHFQYEDFELVGYDPHPAIKMNMSA
What are the official names of this protein?
Thymidylate synthase 3, TS 3, TSase 3.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: NUDC_ECOUT
Sequence: MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQLQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPKELLEAHWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: Y200_NOSS1
Sequence: MNKIAYLQCPTGISGDMCLGTLVSLGVPVAYLTEKLNNLGIAEEYKLRAEKVQRNGQEATKVHVDLLDHHHHDHEHHHHGRHLPEIEQMILQAGLPPRAEAWSLAVFRQLAVAEGSVHGIAPEKVHFHEVGAVDAIVDIVGTCLGLDWLGIASDNAGFPLLYCSAFPTGGGTVRAAHGQMAVPVPAVLKLWEMRGCPVYSNGIDRELVTPTGAAIATTLVKEFGAPPPMTIKQVGLGAGTINLPIPNILRLWLGESANLQANITDSAANSPTLETISVLETQIDDLNPQAIGYVFEQLFAVGALDVFTQPIGMKKSRPGILLTVICHPETLNDCEAVLFCETTTLGIRRTTQQRAVLQREFKPIQTKYGTVRIKIAWHGQSPEKVITNVQPEYEDCAELARKHKIPWREIQQLALQGWYESIQNSK
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: GCSH2_DICDI
Sequence: MNIIKTGIKQSLVSGIYSKVGIRAFCTHYSAELEWVKLSDDNKVATVGLSSFGAQRLGKINYVELPKEHRKCRREEKFGVLESSNATAFGLYAPVSGEVLEVNEKLKKSPSLLNEDPANNWMVKFKVSKPDEFKKLMDSNKYKKFVQWYR
What are the official names of this protein?
Glycine cleavage system H-like protein gcvH2.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: ATPL_THIDA
Sequence: MEMTQAVLYIAGALMMGLGALGAAVGIGVLGGRFLEGAARQPELIPMLRTQFFIVMGLVDAVPMIAVGLAMYVLFAVAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: END4_ECODH
Sequence: MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RL11_VARPS
Sequence: MAKKIVGFIKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAQTQSVEPGLPLPVVITAFADKSFTFIIKTPPAITLIKKAIKLDKGSARPHTDKVGKITRAQLEEIAKTKMKDLTAADLDAAVRTIAGSARSMGVNVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RUVB_LACAC
Sequence: MVILFSEEVKLVAENDDAVTSGHVENPEEEQMELSLRPQTLDQYLGQKRVKKEMSIYIKAARQRDEALDHVLLYGPPGLGKTTLAFVIANELGVHLKSTSGPAIEKAGDLVALLSDLDPGDVLFIDEIHRLAKPVEEVLYSAMEDYYIDIVIGEGQTTHAVHVPLPPFTLIGATTLAGQLSAPLRDRFGIVEHMQYYTVDELEKIVQRSSDVFHTSIAPEAAHELARRSRGTPRVANRLLKRVRDFAEVKGEKTISLATTSDALKQLQVDSEGLDQTDRKLLRTMIEGYNGGPVGIRTLAANIGEDMETIESLYEPYLLQNGFILLTPRGRMVTDKAYLQLGLPIPNDN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HUTI_RUEPO
Sequence: MTLALFHNLTLASMTDGPTPYGLMPKGALVAEAGQVLWSGPQAELPAAFAAVPAHDLGRRLVTPALIDCHTHVVHGGNRANEFEMRLNGASYEEVARAGGGIVSTVSATRTATEAELLASALPRVDAMIAEGVAVIEVKSGYGLDIETELRMLRAARAIGQHRDVTIRTSFLGAHAVPADFAGRADAYIDTVAIPALRTAHAEGLVDAVDGFCEGIAFQPEQIARVFDVARDLGLPMKLHAEQLSNLGGTKLAASYGALSADHIEYLDEDGVAAMARAGMTAVILPGAFYTLRETQKPPVALLRKHRVPMAVSTDANPGSSPMTSLLLAMNMACTLFRLTPEEALAGTTRNAARALGMADRGTLAPGQRADLAVWDVAHPAELAYRIGFNPLYKRIIGGTL
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF3_PHAVU
Sequence: MPRSRINENFIDKTFSIVANILLRIIPTTSGEKRAFTYYRDGMSAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEVAESWFNQAAEYWKQAIALTPGNYIAAQNWLKITGRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: DAPF_SHESW
Sequence: MIQFTKMHGLGNDFMVVDGVTQNVFFSPEQIRRLADRNFGIGFDQLLLVEPPYDPDLDFHYRIFNADGSEVEQCGNGARCFARFVRNKGLTNKNKIRVSTSSGKMTLRLERDGTVTVNMGVPILEPSLIPFKAKKPEKTYLLQTAQQTFLCGAASMGNPHCVLDVEDVASAAVAEIGALLTKHERFPRGVNVGFMQVINSGHIKLRVYERGAAETLACGTGACAAVVVGQIQGKLDQQVRVDLPGGTLTINWEGEGKPLWMTGPAQHVYDGQIQL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFB_YERPS
Sequence: MEGTGLLTAVLVFLFAAVVAVPIAQRLGIGAVLGYLIAGIAIGPWGLGFIRDVDEILHFSELGVVFLMFIIGLELNPAKLWQLRRSIFGVGAGQVVITAAVLGALLYFTQFAWQAAVIGGVGLAMSSTAMALQLMREKGMNRNEGGQLGFSVLLFQDMAVIPALALIPILAGNEGGANDWVKIGLKIAAFAGMLIGGRYLLRPLFRYIVASGVREVFTAAALLVVLGSALFMDALGLSMALGTFIAGILLAESEFQHELEIAIEPFKGLLLGLFFISVGMALDLGVLFTHLLDVLLGVLALVFIKSAILYGLARVFGLRRSVRLQFAGVLSQGGEFAFVLFSAAFSQRVLNAEQLALLLVVVTLSMMTTPLLMQVIDRILVRRYNAQEESDEKPFVEDNDPQVIIVGFGRFGQVIGRLLMANKMRITVLERDVSAVSMMRKYGYKVYYGDATELELLRAAGAEKAKAIVITCNEPEDTMALVHLCQQHFPNLHILARARGRVEAHELLQNGVKDFTRETFSSALELGRKTLLELGMHPHQAYRAQQHFRRLDMRMLRELMPQHHGDVAQISRIKEARRELEDIFQREMLHESRQLDGWDEYE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTU_BORPA
Sequence: MAKGKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLSNKFGGEARGYDQIDAAPEEKARGITINTSHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIIVFLNKADMVDDAELLELVEMEVRELLSKYDFPGDDTPIVKGSAKLALEGDKGELGEQAILSLAQALDTYIPTPERAVDGAFLMPVEDVFSISGRGTVVTGRIERGVVKVGEEIEIVGIKPTVKTTCTGVEMFRKLLDQGQAGDNVGILLRGTKREDVERGQVLAKPGSINPHTDFTAEVYILSKEEGGRHTPFFNGYRPQFYFRTTDVTGTIDLPADKEMVLPGDNVSMTVKLLAPIAMEEGLRFAIREGGRTVGAGVVAKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTK_DROME
Sequence: MQLNLGAIFLALLGVMATATSVLAEPHRHQGPIFDTRPSPFNPNQPRPGPIY
What is the function of this protein?
Potent antifungal and antibacterial activity against Gram-positive bacteria.
What are the official names of this protein?
Metchnikowin.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIE_RALPJ
Sequence: MSQTHFGFQQVDEQEKAGKVAGVFHSVASKYDVMNDLMSGGLHRVWKMFTIAQAAVRPGYKVLDIAGGTGDLAKAFARQAGPTGEVWLTDINESMLRVGRDRLLDAGVLTPTALCDAEHIPFPNAYFDVVTVAFGLRNMTHKDRALAEMRRVVKPGGKVMVLEFSKVWQPLEKAYDVYSFKVLPWLGSKVAGDPESYRYLAESIRMHPDQETLKQMMEQAGLDSVEYFNLTAGVVALHVGRRL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PSAC_SKECO
Sequence: MSHTVKIYDTCIGCTQCVRACPTDVLEMVPWDGCKSGQIASSPRVEDCVGCKRCETACPTDFLSVRVYLGAETTRSLGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RL23_ALKOO
Sequence: MTNPHDIIIKPIITENSMDDMASKKYTFAVNKKANKIQVKQAVEAVFGVKVEKVNTMNMIGKVKRMGAKEGKRADWKKAIVTLRPDSKEIEFFEGM
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: DOTC_DOTSN
Sequence: MSEDHTKADNLSEKDPHSPERSDSSSHEDAHAREEEESSDDDGALDGKPASLIAIVMIALSLAVFLSALDTTIVTVALPAISAHFNSTAAYTWVGSAYLLANAASTPIWGKLADIFGRKPMLLLANALFMIGSLVCALSINVGMLITARAIQGAAGGGLLTLVDTIIGDLFSLRTRGTYLGMIGGVWAIACALGPIVGGAFTSSVTWRWCFYINLPIDGLAFGIIFFFLKLKTPKTPILEGFAAIDWAGSFFIIGGTLMFLFGLQYGGITFPWDSATVICLLVFGVVCIVLFGLVEWKFARFPIIPLRLFQYRNNCGALLVAFFHSFVFISAFYYLPLYFQAVKGATPILAGVYILPAVLSTGVSAAATGAFIGNTGNYLIPMYFGMSMMILGYGLLINFDAGSGWAKLIIYQLIAGIGNGPNFQAPLVALQTKIKQSDIATGTATFNFVRNIATAISVVAGQVLYQNQLKKMTSTLQQLGPAASLIAAGDAGANTQAINALPTPQRDLARSAIADALSPMWIMYTAFAAAGLFCILLVSKTELTTTHEVTEVGLEAQKKAEAERKAERQAKDLEKAQKS
What is the function of this protein?
Efflux pump; part of the gene cluster that mediates the biosynthesis of dothistromin (DOTH), a polyketide toxin very similar in structure to the aflatoxin precursor, versicolorin B (PubMed:12039746, PubMed:17683963).  One function of dotC may be to transport early-stage dothistromin biosynthetic intermediates from the cytoplasm into vacuoles, thereby affecting the rate of dothistromin production (PubMed:22069539).
What are the official names of this protein?
Efflux pump dotC, Dothistromin biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: SEY1_SCHJY
Sequence: MQQSAQLITENKEFNEDFPRFLKDVGLDNVGFDYHVVAVLGSQSTGKSTLLNKLFGTQFSTMDTVRRQQTTKGIWVSRGKDSSILIMDVEGTDGRERGDDQDFERKSALFSIATSEVIIVNMWENQIGLYQGSNMTLLKTVFEVNLQLFHENIERSRLQFVIRDFLGSTSLDNLSETLMTDLNRTWASISKPEGLENSVITDFFDVDFSALPHKVLCAEAFDEETDKLREQFLDEKNPKYLFKPCYHKRIPADGFPLYTQGIWQLIQNNRDLDLPTQQQLLAQYRCDEFIAEAMVSFDEQCEELLTFLKTHQSIENLLQRLEAIQTSTFSIFDENARRYQSEVYTKKRQELDRMMKTRLAVPIQRYLAAIHKELVAGFPERIATLVKDACFKDVARVTVSEMVSVMHSEAAALQKEGFVCDAEQTVETLRVELLQLVRSMREERLAQISAKLMVQFEQEFADAIDVSFHHLTKDIWDNIMHKFDELREKVLDEMLRSLNEYIDDEMDEDAELLRTKHMFKLKRSTWLVLRRTLENETAEPILQQRLRTHFEDSFRYDSRGIPKMWKKSDILENDFNKSLQDTLQLIDVLAIVRLKDGSVPTVDVPLAEEGEDTASNLEADTFFTFLNRKKKANIHVSVKRAADLVFLDCKRSIISTATRVPGYFWALLAVLGWNEFVSVLKNPVLLTLLLIVVSFLFILVQTGLAGPVKAFAERSVRNAVNSMGEKLAEKLDDYRSTSPASETTSGRVISAENSSVDEKVSTTP
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein sey1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: VSPH1_PROJR
Sequence: MVLVRVLANLLMLQLSYAQKSSELIIGGDECNINEHRFLVALYTFRSRRFHCSGTLINEEWVLSAARCDRKNIRIQLGMHSTNVINEDVQTRVPKEKFSCLSSKTYTKWNKDIMLIRLKKPVNNSTHIAPVSLPSNPPTLGSVCRVMGWGTISATKETHPDVPLCANINILDYSVCRAAYARLPATSRTLCAGILEGGIDTCKGDPGGPLICNGQFQGIVSWGSDPCAKPHEPGSYTKVFDHLNWIQSIIAGNTTATCPP
What is the function of this protein?
Snake venom serine protease homolog that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease homolog, SP1, Venom serine proteinase-like protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CTXI3_MESEU
Sequence: MCMPCFTTDHQTARRCRDCCGGRGRKCFGQCLCGYD
What is the function of this protein?
Toxin with unknown function in healthy organisms.  On glioma cells, interacts with chloride channels (probably ClC-3/CLCN3) and MMP2 at the surface of glioma cells.  This complex is then internalized via caveolae, thus inhibiting the chloride channels necessary for cell shrinkage and tumor propagation.
What are the official names of this protein?
Insectotoxin-I3, BeI3.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Chloride channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.