PharMolix/UniProtQA huggingface dataset:
Protein: DXS_CHLFF
Sequence: MTSQVSSILSRISSPTDLKNLSLAELSLLAEQMRHKIISVLTNTGGHLASNLGIIEVTIALHYVFSSTEDKFIFDVGHQAYPHKLLTGRNTEEFDRIRHDGGLSGFTSPSESMHDLFFSGHAGNALSLALGMAKATEDSRTHILPILGDAAFSCGLTLEALNNISSNLSKFIVILNDNNMSISQNVGVMSKNLSRWIHHPKFSLFSRKIEKWLTKIPRYGNGISKRSHKLSTCLKSLFCPIPIFEQFNLAYMGPVDGHNIKRLISVFQTARDLPFPVLIHICTTKGKGLEIAQENPEKYHGVTANFNSSEKNKLLPTIKPQLTYPDVFGQTVCKLGETSPNLHIVTPAMSLGSRLEAFKEKFPKRFIDVGIAEGHAVTFSAGIAKAKSPVICSIYSTFLHRALDNVFHDVCLQGLPVILAIDRAGLAYGDGCSHHGIYDISFLRAMPNMIICQPRSAIVLQQLLQSSLQWNMPSAIRYPNIAAIQRDPIATDVNMHRDPGLGEILSQGEDILIIGLGHMCNTALSIKLQLLTHGISATVVDPVFIKPFDNNLFSILLMHHSKVIIIEEHSIRGGLASEFNDFLATYGFKVDVLHFGIPDAFFSHGDKESLLKRVGLDTESMVKRILTHFNFRTKTSPSNKLSIV
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: DAPF_PSYA2
Sequence: MLIEFTKMHGLGNDFMVIDLVTQRLDLTKDLVQLLGDRHLGIGFDQLLVVEPPMRPDVDFSYRIFNTDGTEVEQCGNGARCFARFVQARKLSFKQRLRVETASGIISLTTDHYGWVEVDMGKPKFEPSEIPFTPRATTKIQNAYHLDVNGTPVQLYVANMGNPHAVIKVDDVLDADVESLGRAIESHPAFPERVNVGFMQVMNQRHIRLRVYERGVGETQACGTGACAAVAIGIREGWLDEGEDVRAQLYGGSMVIKWQPGYSVMMTGPTAFVYEGVFSPDGLMAQAGIKPNPEI
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBPB2_HAEIN
Sequence: MPRRPPFWLTLLIILIGLPLCLPFLYVILRATEVGLTRSVELLFRPRMAELLSNTMLLMVCVTIGAISLGTFCAFLLERYRFFGKAFFEVAMTLPLCIPAFVSGFTWISLTFRVEVFWGTIGIMTLSSFPLAYLPVSAILKRLDRSLEEVSLSLGKSPVYTFWYAISPQLKPAIGSSILLIALHMLVEFGAVSILNYQTFTTAIFQEYEMSFNNSTAALLSAVLMAICILIVFGEIFFRGKQTLYHSGKGVTRPYLVKTLSFGKQCLTFGFFSSIFILSIGVPVIMLIYWLIVGTSLESAGDFSEFLSAFSNSFIISGLGALLTVMCALPLVWAAVRYRSYLTIWIDRLPYLLHAVPGLVIALSLVYFSIHYANDLYQTFFVIIIAYFMLYLPMAQTTLRASLEQLSDQIEKVGQSLGRNPFYIFRTLTLPAILPGVAAAFALVFLNLMKELTATLLLTSNDIKTLSIAVWEHTSDAQYAAATPYALMLVLFSGIPVFLLKKYAFK
What is the function of this protein?
Part of the ABC transporter complex FbpABC (TC 3. A. 1. 10. 1) involved in Fe(3+) ions import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Fe(3+)-transport system permease protein FbpB 2, Iron(III)-transport system permease protein FbpB 2.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FbpB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAA_LEPIC
Sequence: MVIHKKIAVVDFGGQYAHLIASRIRRLGAYTEILSNEEPISNYQKYSGIILSGGPESVYEPNSPTVTTRIFDLGIPILGICYGHQLIMKLLGGVVERSGTGEYGPASLQLHGTNGNSILKNFVGGEQVWMNHADEVVKLPEGFSKIAFSKDCGYAVVANSSKKIFGIQFHAEVSHSEKGSVLLDNFIQICGVSKTWGIDQFLKEKIKEIQETVKQEQKIFMLVSGGVDSTVSYLLLCKALGAERVLGFLIDTGFMRKDEVVSLQKKLTFQNIHLTVRDESSLFYKSLKDKSDPEEKRKIVGNLFLEARDRAVKDLDLEYGDWLLGQGTIYPDTIESGGTKHSHTIKTHHNRVEAIQKLIEQGKVIEPIRDLYKDEVRDLGVLLGLESEWVGRHPFPGPGLVVRMLAVEKKGTDKDQLEIDSYLSTQDGLSGKILPIASVGVKGDRRSYANCVVLNDIETDWNTLDRVATHLSNRFSFINRVVLLPFESDLKKWNFQFTGMQLDKKCSDLLREADFTVESVIRKLGLYNKIWQMPVVLLPIGEKENEKSIVLRPVESQEAMTANFFRMERSVLQEIKIEVLKIPEIRYLFFDLTNKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
Probable GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: Y1459_HAEIN
Sequence: MSFISYISFKGIKMNVISDLELQQIRTQMLTFAQLQVNQADLAEDLVQEAFLSAFKNLANFKRQSAFKTWIFAILKNKIIDYLRQKGRFVLESELEDENTNNSFFDEKGHWKPEYHPSELQGEEETVYSDEFWLIFETCLNCLPAKQAKIFMMREFLELSSEEICQETHLTSSNLHTTLYRARLQLQNCLSKKL
What are the official names of this protein?
Probable RNA polymerase sigma factor HI_1459.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: ADRX_YEAST
Sequence: MLKIVTRAGHTARISNIAAHLLRTSPSLLTRTTTTTRFLPFSTSSFLNHGHLKKPKPGEELKITFILKDGSQKTYEVCEGETILDIAQGHNLDMEGACGGSCACSTCHVIVDPDYYDALPEPEDDENDMLDLAYGLTETSRLGCQIKMSKDIDGIRVALPQMTRNVNNNDFS
What is the function of this protein?
Required for Fe-S cluster incorporation into mitochondrial and cytosolic apoproteins.  May be part of a novel electron transport chain.
What are the official names of this protein?
Adrenodoxin homolog, mitochondrial, Mitochondrial ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL15_COXBU
Sequence: MQLNDLKPAKGARHQKLRVGRGIGSGKGKTAGRGHKGQHSRAGGYHKVGFEGGQMPLQRRVPKFGFTSRKELISAEVRLGELNKISGDVVDLASLKAANIISRQIKRVKIFAAGKLEKPVTIRGLRVTKGVKAAVEAAGGKIE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: HSP71_PARBA
Sequence: MAPAIGIDLGTTYSCVGIFRDDRIEIIANEQGNRNTPSFVAFTDTERLIGDAAKNQVAMNPQTVFEAKRLIGRKFADPEVQADMKHFPFKITDKGGNPKIQVEFRGEGKHFTPEGISSMFRRKKREIAESYLGGTVNNAVVTVPAYFNDSQRQVTKDAGLIAGLNVLRIINEPTAAAIAYGLDKKAEGERNVLILDLGGGTFDVSLLTIEEGIFEVKSTAGDTHFGGEDFDNRLVNHFVNEFKRKHKKDLSSNARALRRLRTACERAKRTLSSAAQTSIEIDSLYEGIDFYTSITRARFEELCQDLFRSTMDPVERVLRDAKIDKSSVHEIVLVGGSTRIPRIQKLVSDFFNGKEPNKSINPDEAVAYGAAVQAAILSGDSTSKSTNEILLLDVAPLSVGIETAGGVMTPLIKRNTTIPTKKSETFSTFADNQPGVLIQVFEGERARTKENNLLGKFELTGIPPAPGVPQIEVTFDVDANGIMNVSALEKGIGKTNKIVITNDKGRLSKEEIERMLAEAEKYKAEDEAEASRISAKNGLESYAYSLRNTISDSKVDEKLDASDKEKLKTEIDKTVSWLDENQTATKEEFEAQQKELESVANPIMMKFYGAGGAPGAGFPGAGGPGGFPGAGVGGAHSGGDDGPTVEEVD
What are the official names of this protein?
Heat shock 70 kDa protein 1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS12_LACPL
Sequence: MPTINQLIRKGRKSKVSKSNAPALNFGYNSYKKVATNNPAPQKRGVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHVIRGALDTAGVEDRRQSRSKYGTKKPKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MYTB_MYTED
Sequence: SCASRCKGHCRARRCGYYVSVLYRGRCYCKCLRC
What is the function of this protein?
Has antibacterial and antiviral activity.
What are the official names of this protein?
Mytilin-B.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_SYNP6
Sequence: MANIKSAIKRVQIAERNRLRNKAYKSAVKTLVKHCFTAFDAYAADPNETARQAVNERLSAAYSKIDKAVKRGVLHANTGARKKARLAKAFHLKVDPQA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: INS1A_CONTU
Sequence: MTTSFYFLLMALGLLLYVCQSSFGNQHTRNSDTPKYRCGSEIPNSYIDLCFRKRNDAGKKRGRASPLWQRGGSLSMLKARAKRNEAFHLQRAHRGVVEHCCHRPCSNAEFKKFCG
What is the function of this protein?
This venom insulin, from a fish-hunting cone snail, facilitates prey capture by rapidly inducing hypoglycemic shock (PubMed:30747102).  It is one of the smallest known insulin found in nature and lacks the C-terminal segment of the B chain that, in human insulin, mediates engagement of the insulin receptor (INSR) and assembly of the hormone's hexameric storage form (By similarity).  Despite lacking this segment, it both binds and activates human insulin receptor (long isoform (HIR-B)) with a high potency (EC(50)=12. 0 nM) (PubMed:30747102).  In vivo, intraperitoneal injection of this peptide into zebrafish lowers blood glucose with a lower potency than human insulin (PubMed:30747102).  In addition, when applied to water, this peptide reduces overall locomotor activity of zebrafish larvae, observed as a significant decrease in the percentage of time spent swimming and movement frequency (By similarity).  When tested on a mouse model of diabetes, this insulin also lowers blood glucose with a 10-fold lower potency than human insulin (PubMed:30747102).
What are the official names of this protein?
Con-Ins T1A, Con-Ins T1, Insulin 1.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDE_ECOLU
Sequence: MSDIALTVSILALVAVVGLFIGNVKFRGIGLGIGGVLFGGIIVGHFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVIIGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMEMVDQMGMSYAMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESSRTNGGALIRTINIRVENPNLHDLAIKDVPILNGDKIICSRLKREETLKVPSPDTIIQLGDLLHLVGQPADLHNAQLVIGQEVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASGDISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVPGFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKSGGDFVNTLVNGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPPALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG
What are the official names of this protein?
Putative transport protein YidE.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVB_ECO45
Sequence: MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MIND_TUPAK
Sequence: MLFFFKAPKFMYGSIKRKNLCFATSTIDISEEDNTDTKTSSRIIVVTSGKGGVGKTTATANIGMSIARLGYKVVLIDADIGLRNLDLLLGLENRILYTVMDVFEGQCRLDQALIRDKRWKNLSLLSISKNRQRYNVTRKNMQNLVKALANLNFRYILIDCPAGIDVGFINAISPAQEALIVTTSEIPAIRDADRVAGLLEANGIFDIKLLINRVRSDLIQKNDMMSVRDVQEVLGVPLLGAIPEDNQVIVSTNRGEPLVLKKKLTLSGIAFENAARRLVGKQDYFVDLDSPYKGVFQKIFDLFSGN
What is the function of this protein?
ATPase required for the correct placement of the division site.
What are the official names of this protein?
Putative septum site-determining protein MinD.
What is the protein family that this protein belongs to?
Belongs to the ParA family. MinD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KCY_STRPI
Sequence: MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYMALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAIAAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKENIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAEAEKRM
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_BURP1
Sequence: MAVNFPSIDPAQLHPVAGVTLGWAEANIRKPNRKDVLVVSVEEGATVSGVFTENRFCAAPVTVCREHLAKVRAGGAGIRALVVNTGNANAGTGEPGLAHARETCAELARLAGIAPGQVLPFSTGVILEPLPIERLKAGLPAALANRAAANWHDAAQAIMTTDTLPKAASRQVTIDGHTITLTGISKGAGMIKPNMATMLGFLAFDAKVAQPVLDALVKDVADRSFNCITIDGDTSTNDSFILIASGKASLPQIASTDSPAYAALREAVTAVAQALAQLIVRDGEGATKFITVTVEGGKSAAECRQIAYAIGHSPLVKTAFYASDPNLGRILAAIGYAGVADLDVGKIDLYLDDVLVAKAGGRNPAYLEEDGQRVMKQSEIAVRVLLGRGDAQATIWTCDLSHDYVSINADYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSF_TABYA
Sequence: MTSIPVSSFLLAALVLQYATSDAVNYCRLPCRGDNYHVGCGEPAYAQECGQSPRTRELLKEHRNEILSKINDVRDHVAKGSWGLPVAARMKVVVWDAELAGLAKRHTKGCVGETHACRNTERFWLPGQLNFKYSGDKLPRIKELIDDAVKKGHLQKHNITREIIGNYRENGPNGDVKELALAISDRVTAVGCGLTTWQDGAKARALLTCNFSSQNTRGRPVYKIGNSPGEKCIEKDETYKNLCPATEPIDPNKSN
What is the function of this protein?
Anti-inflammatory scavenger of eicosanoids and antithrombotic protein that inhibits platelets aggregation induced by collagen, ADP and convulxin (GPVI agonist) (PubMed:21475772, PubMed:22311975).  Exhibits high affinity binding for glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) and endothelial cell alphaVbeta3 (ITGAV/ITGB3) integrins, but not for alpha-5/beta-1 or alpha-2/beta-1 (PubMed:21475772).  Accordingly, it blocks endothelial cell adhesion to vitronectin (IC(50)~1 nM) and marginally to fibronectin (IC(50)~1 uM), but not to collagen (PubMed:21475772).  It also inhibits fibroblast growth factor (FGF)-induced endothelial cell proliferation, and attenuates tube formation in vitro (PubMed:21475772).  In addition, it dose-dependently attenuates thrombus formation to collagen under flow (PubMed:21475772).  Also binds proinflammatory cysteinyl leukotrienes (leukotrienes C4 (LTC4), D4 (LTD4) and E4 (LTE4)) with submicromolar affinities (PubMed:22311975).
What are the official names of this protein?
Tablysin 15, Disintegrin.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: XYLA_LEVBR
Sequence: MTEEYWKGVDKIQYVGHQDKKSGLGFQYYNPEEEIMGKKMKDWLRFAVAYWHTFDQRLVDPFGDGTAQRPYDKYTDPMDLALAKVDAAFEFYQKLGVDYLCFHDRDLAPEGDTLRETNANLDKVVDKIVEYQKTSGMKVLWNTSNMFTNPRFVEGAATSPYADVFAYSAAQLKHSLEIGKRVGSENYVFWGGREGYESLWNTNMKQEQEHAAKIFHMAKDYANEIGFDAQMLLEPKPKEPTTHQYDFDAATTIAFMKEYDLDKDFKLNLEGNHANLAGHTYQHEIRVAREAGLLGSLDANQGDKLIGWDIDEYPSNLYETTAAMYEVVENGSIGPRGGLNFDAKPRRSAFAPEDLFLGHIVGMDSFAAGLRVAAAMKQDGFLDNLKADRYSSYKSGVGADIESGKADLKSLEAYAIDKPQSELIAATHSDHLEEIKDTINHYIIDTLSK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_HERAR
Sequence: MSRIQSTFAALAAKNKKGLIPFITAGDPAPDLTVPLMHALVAGGADILELGVPFSDPMAEGPVIQRACERALKFNVSLHDVLGFVSEFRKTDTTTPVVLMGYANPIERMGQTAFVLAAKAAGVDGTIVVDYPPEECEEFAATLKANDMDPIFLLSPTSTEERIQQVAKFGSGFSYYVSLKGVTGSANIDTQDVAQRIEAIRKHVKLPIGVGFGIRDAATAKAVATVSDAVVIGSRIIQELENTPRERAVEAAQTFISGIRKALDE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: MED6_PONAB
Sequence: MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHLNQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFKEHEEQDKVRPKAKRKEEPSSIFQRQRVDALLLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPVPETVKPEEKETTKNVQQTVSAKGPPEKRMRLQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 6, Mediator complex subunit 6.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNZ_BACC2
Sequence: MEFVFLGTGAGVPSKGRNVSAIALQLLEERGQTWLFDCGEATQHQILHTSVRPRRIEKIFITHLHGDHIFGLPGLLGSRSFQGGTTPLTVYGPKGIKQFIEVALSVSTTHVKYPLEVVEITEEGTVFEDNEFYVETKRLSHGIECFGYRIVEKDIQGALLVDKLLEMGVKPGPIFKRLKDGEVVELEDGTILNGNEFIGPPQKGRIITILGDTRYCEASRELAQDADVLVHEATFAAEDEQQAHDYFHSTSKQAASIALQANAKRLILTHISSRYQGDTYKELLKEARELFSNTEIATDLKSFPVEK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: KV228_HUMAN
Sequence: MRLPAQLLGLLMLWVSGSSGDIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 2-28.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: ARGA_VIBVY
Sequence: MKIRSTALVKGFRQSTPYVNAHRGKTMVILLGGEAIADKNFSNIINDIALMHSLGVKVVLVYGARPQINQLLDKQSSQTPYHKHIRVTDENSLSIVMQAAGQLQLAITASLSMSLNNTPMAGTHLNVVSGNFVIAQPLGIDEGVDYCHSGRIRRIDTEAINRSLDQGSIVLLGPIASSVTGECFNLLSEEVATQVAIKLKADKLIGFCSEQGVIDEEGNAVAELFPSDAEKFIQKLSVDVDPDSDFHSGTLRFLKGAVAACRAGVPRSHLISYKIDGALIQELFSFDGIGTQVVMASAEQVRQACIDDIGGILELIRPLEEQGILVRRSREQLEQEVERFTIIEKDGLIIGCAALYPYIDEHMAEMACVAIHPDYRDGNRGLLLLNYMKHRSKSIGIEQIFVLTTHSVHWFREQGFYEIGVDSLPMAKKSLYNYQRRSKILALPL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TV23B_PONAB
Sequence: MLQQDSNDDTEDVSLFDAEEETTNRPRKAKIRHPVASFFHLFFRVSAIIVYLLCELLSSSFITCMVTIILLLSCDFWAVKNVTGRLMVGLRWWNHIDEDGKSHWVFESRKESSQENKTVSEAESRIFWLGLIACPVLWVIFAFSALFSFRVKWLAVVIMGVVLQGANLYGYIRCKVGSRKNLTSMATSYFGKQFLRQNTGDDQTS
What are the official names of this protein?
Golgi apparatus membrane protein TVP23 homolog B.
What is the protein family that this protein belongs to?
Belongs to the TVP23 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KRFT_ANAPL
Sequence: SCYDLCRPCGPTPLANSCNEPCVRQCQDSRVVIQPSPVVVTLPGPILSSFPQNTAVGSTSAAVGSILSEEGVPISSGGFGLSGFGGRYSGRCLPC
What are the official names of this protein?
Feather keratin B-4, F-ker.
What is the protein family that this protein belongs to?
Belongs to the avian keratin family.
Protein: DHQS_META3
Sequence: MKFGWIMANDEDWEERKETVKDSLESSIPAVMVYEEDIEKVKELGNIKTISKNPNSDIVVIDKGDDLTILFDAKKEGKETGVFISIECKEDEEYASEVSRYDYVDYIILEGKDWNIIPLENLIADLFDENIKIVSLAKDINDARTAYEILERGVDGVLYVPKDINDVKDFATLIEKMNSEKLDLDCATITKVEAIGSGDRVCIDTCSMMEMGEGMLIGSYSRALFLVHAETVENPYVATRPFRVNAGPVHAYVLCTGNKTRYLSELKAGDGILIVDKDGMTREGIVGRVKIEKRPLMLIEAEYVGGEIVRTIVQNAETIRLVNENGAPISVVDLKVGDKVKLKIDTNARHFGMAIQETIIEK
What is the function of this protein?
Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.
What are the official names of this protein?
3-dehydroquinate synthase, DHQ synthase, 3-dehydroquinate synthase II.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type DHQ synthase family.
Protein: Y620_STRSY
Sequence: MSDKLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPTLLPKFLELIRHSQDNNKIALVVDMRSRSFFSEIREVLDEIEGAEDLDFKVLFLDATDSELVARYKETRRSHPLAADGRVLDGIQLERELLAPLKNMSQNVIDTTELTPRNLRKVISEQFASQDNQPSFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYKLELRNLTGLDAPVFDYVMEHQESEEFYSHLLGLIEPILPGYQKEGKSVLTIAVGCTGGQHRSVAFAKRLADDLEKNWNVNRSHRDKDRRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SSU05_0620.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: ASTE_ERWT9
Sequence: MQDFLQLTLSGGQPEQKEGRNGLLRWRWLNVGILELTPLHSVPRALVVSSGIHGNETAPVEIVEQLVNALLRGELALQARLLVIYGNPAALRLNRRYVHGDMNRMFGGRWQQYEDCPEARRAWILEQAMDNFWQAGDYEEVRWHLDLHTAIRGSYHAQFGVLPQRMTPWPEDFMHWLASAGLEALVFHRATGGTFTNYSSRHFQAASCTLELGTALPFGHNDLTQFAAVRLALRQLIAGGENIPAAAQPRRYRVSQQITRRSDRFVLHMSDEVLNFTAFPQGTLLAEDGEDRVYVQQAREYVLFPNPNVATGLRAGLMLVEDNVHNKAL
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.