PharMolix/UniProtQA huggingface dataset:
Protein: Y057_METAR
Sequence: MPNYKVVLEAAWIVKDAKSVDDAMSVAISEAGKRLNAAKMDFVEVEVGGTFCPFCGEPFDSVFVVAGTGIVGLLLEMKVFNAESKEHAERIARKGIGKALRDVPLKVVDITEAE
What are the official names of this protein?
UPF0212 protein UNCMA_00570.
What is the protein family that this protein belongs to?
Belongs to the UPF0212 family.
Protein: APTH1_CANGA
Sequence: MSTAVRIASTKKPAKYALIFLHGLGDTGQGWSFLAQYLQQYHPCFESTNFIFPNAPIKPVTANGGMPMPSWFDIKVWDWTTSNVDTVGFQQSLKEVQKYVDSSISDGIEPQNIIVGGFSQGAALALASAVTLNNKIGAFIGLSGFAYLRNELQETRKNLNPNTPVFHGHGESDDVVPFPIGVQTAEFFKSAGELENYTFKSYRGLGHSADPAELNDLAEFLKSNVYSKDA
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates.  Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins.  Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.
What are the official names of this protein?
Acyl-protein thioesterase 1, Palmitoyl-protein hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PUR5_NITWN
Sequence: MTDRNISLTYAGAGVDIDAGNRLVDLIKPMVRATARAGAEAEIGGFGGLFDLKAAGFADPVLVAANDGVGTKVKIAIETGIHDTIGIDLVAMSVNDLVVQGAEPLFFLDYFACGKLDPETAAAIVAGIAEGCREAGCALIGGETAEMPGLYKDGDYDLAGFAVGAAERGSLLPGRDIAAGDAVIGLASSGVHSNGYSLVRNIVEASGIALSAPAPFAPVATLGGALLTPTRLYVKSCLRAIRETGAVKGLAHITGGGFTDNIPRVLPEGLGVRIDLAGLTVLPVFKWLAQQGRVVEREMLRTFNCGIGMVAIVRRDAVQQVVDVLTQAGERVSLLGDVIVAGDEGRVVYDGQLDLAV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_VIBPA
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIDNAPGVHGARRGRLSEYGVQLREKQKVRRMYGVLEKQFRNYYKEAARLKGNTGENLLQLLEGRLDNVVYRMGFGATRAEARQLVSHKAILVNGKVVNVPSFKVAANDVVSIREKAKQQARIKAALEVAEQREKPTWIEVDGGKMEGTFKRMPERSDLSADINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL2_PYRHO
Sequence: MGKSLIQQRRGKGSPTFRSPSHRFRGAVKYIPLNYTQDKTIRGVVEEIMHDPGRTAPVARVKFENGMEKLIIAPEGLLVGQEIYIGPDAPVEIGNTLPLAKIPEGTYIYNIEGVPGDGGKYVRAGGTYALVVSREKDKVIVQLPSGELKAFDPNCRATIGVVAGGGRLEKPLVKAGKAYYKYKARNKFWPTPRGVKMNAVNHPFGGKEHHPGKPTTTSRRAPPGRKVGHIAARRTGRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GR22C_DROME
Sequence: MFASRSDLQSRLCWIILKATLYSSWFLGVFPYRFDSRNGQLKRSRFLLFYGLILNFFLLLKMVCSGGQKLGIPEAFARNSVLENTHYTTGMLAVFSCVVIHFLNFWGSTRVQDLANELLVLEYQQFASLNETKCPKFNSFVIQKWLSVIGLLLSYLSIAYGLPGNNFSVEMVLINSLVQFSFNCNIMHYYIGVLLIYRYLWLINGQLLEMVTNLKLDCSVDSSRIRKYLSLYRRLLELKGYMVATYEYHMTLVLTTGLASNFLAIYSWIVLDISMNINFIYLLIFPLFLLVNVWNLWLSIAASDLAENAGKSTQTVLKLFADLEVKDIELERSVNEFALLCGHCQFNFHVCGLFTINYKMGFQMIITSFLYLIYMIQFDFMNL
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 22c.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr22e subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAFA2_PONAB
Sequence: MNKRYLQKATKGKLLIIIFIVTLWGKVVSSANHHKAHHVKTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVTGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRVTH
What is the function of this protein?
Has a role as neurotrophic factor involved in neuronal survival and neurobiological functions.
What are the official names of this protein?
Chemokine-like protein TAFA-2.
What is the protein family that this protein belongs to?
Belongs to the TAFA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RR4_EPIVI
Sequence: MSRYRGPSLKKIRRLGALPGLTNKRSKAENDFIKKLRSDKKSQYRIRLEEKQKLRFNYGLRERQLRKYFSIAIKTRGSTGKVLMQLLEMRLDNIIFRLGMASTIPAARQLVNHRHVLVNGRIVDIPSYRCKSRDIIMARDEQQSNTFINNCINYSTHNRMEAPNHLTLLHPFKGLVNQIIDSKWVGFKINELLVVEYYFRKT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
Plastid 30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid.
Protein: PH4H_RHILO
Sequence: MSVAEYARDCAAQGLRGDYSVCRADFTVAQDYDYSDEEQAVWRTLCDRQTKLTRKLAHHSYLDGVEKLGLLDRIPDFEDVSTKLRKLTGWEIIAVPGLIPAAPFFDHLANRRFPVTNWLRTRQELDYIVEPDMFHDFFGHVPVLSQPVFADFMQMYGKKAGDIIALGGDEMITRLYWYTAEYGLVQEAGQPLKAFGAGLMSSFTELQFAVEGKDAHHVPFDLETVMRTGYEIDKFQRAYFVLPSFDALRDAFQTADFEAIVARRKDQKALDPATV
What are the official names of this protein?
Phenylalanine-4-hydroxylase, PAH, Phe-4-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Protein: BMP2_HUMAN
Sequence: MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis (PubMed:18436533, PubMed:31019025, PubMed:24362451).  Induces cartilage and bone formation (PubMed:3201241).  Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2 (PubMed:15064755, PubMed:17295905, PubMed:18436533).  Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A (PubMed:7791754).  In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.  Can also signal through non-canonical pathways such as ERK/MAP kinase signaling cascade that regulates osteoblast differentiation (PubMed:20851880, PubMed:16771708).  Stimulates also the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A-ATF4 pathway by stimulating EIF2A phosphorylation which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation (PubMed:24362451).
What are the official names of this protein?
Bone morphogenetic protein 2, BMP-2, Bone morphogenetic protein 2A, BMP-2A.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: FPG_PSEP1
Sequence: MPELPEVETTRRGIAPHLEGQRVSRVVVRDRRLRWPIPEDLDVRLSGQRIVSVERRAKYLLINAEVGTLISHLGMSGNLRLVELGLPAAKHEHVDIELESGLMLRYTDPRRFGAMLWSLDPLNHELLLRLGPEPLTDLFDGERLFQLSRGRSMAVKPFIMDNAVVVGVGNIYATEALFAAGIDPRREAGGISRARYLKLAIEIKRVLAAAIEQGGTTLRDFIGGDGQPGYFQQELFVYGRGGQPCKVCGTELREVKLGQRASVYCPRCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RL1_BUCCC
Sequence: MKKKKKNYTFNKKNKKIYNIKEAIQLLKNKKSAKFIESIDAAFNLNIDPKKSEQNVRGSVLLPHGTGNTIKIAVFTTGKNIKIAQLAGADYVGLEDLANLITNQKKKIDLVIASPETMHIVGKLGPILGPKGIMPNPKFGTITKDIKKAIQEAKKGKINYRNDKNGIIHSNFGKINFSEKELYENFLTLYQDIKKSQPNQFKGIYYKKINISTTMGPGIIIDHLSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: AAEX_YERPP
Sequence: MSLLPVMVIFGLSFPPIFLELLISLALFFVVRRILQPTGIYEFVWHPALFNTALYCCLFYLTSRLFS
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OHRL_STAAC
Sequence: MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
What are the official names of this protein?
Organic hydroperoxide resistance protein-like.
What is the protein family that this protein belongs to?
Belongs to the OsmC/Ohr family.
Protein: FTSZ2_THEKO
Sequence: MVFKLLEQAGIKIDLDDEPKKVQTAPQFDDDDENEIRIVIVGVGGSGNNTITRLYDLGVQGAELIAMNTDAQALKHAKAHKKLLLGKDLTQGKGSGGDPEVGYRAAEASAHEIAETIGDADLVFITAGMGNGTGTGAAPVVARVIKERARHNGRFREPLVISVVTYPFKNEGKIREEKAKAGIKALLYYSDTVVIIENDKLLQLVPKLPINAAFRFADEIIARMVKGITETIKLPSMVNIDFADVYSIMHNGGAALIGIGESDSSNRAVDAVKNALQNKLLDVEYGSGEKALVHFTVGPDVSLGEINEAMNIVYEKLGEKSEIKWGARIDEDMGKMVRAMVIMTGVKSPHILGGETALQLPVKESLLPAEPKAGFNSFEDKIYKVISRKSDEKPGSDMRGYINKLLADFDDLS
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ 2.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: LGT_STRPD
Sequence: MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMFIEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PELF2_ASPTN
Sequence: MTLIRTVLMAAALLGASAHAQGVVGKPFGFAAGTTGGGNAAPAAPSDIKELAQWLSDDTPRVILIDKEFDFTGSEGTCADCACCVPSSNTCGSSGQNAIETSFGWCGSSPNVTCTYDKAGTKGMDVGSDKSIVGVGSAGVIRGKGLRLTGGASNVIIQNIHITDINPEYIWGGDAISLDGTDKIWIDHVKISLVGRQMFVTGYESSGSVTISNSEFDGRTSWSASCDGHHYWTLLGLGKNEQITFARNYIHHTSGRSPKLGESSYWHSYNNYWSDNSGHAFDVESAGKSLIEGNVFSNVKTPLTKENLDGVFAVSADDESTCSGSLGRSCIPNVLTSSGELSSAGDGVFSGWLSDEGDLTLMPASQVASYVKAHAGVGKLGAGDYSSSAIPSSTPAPSSSALAKRHGGHDRHGLGHIPHLTEGGPGAWHTPGPAPSWSWRTIGVRSTALPTPSPSSSSCAIGKPTAGPPRFPIFGDLGIF
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
What are the official names of this protein?
Probable pectin lyase F-2, PLF-2.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y5655_PARPJ
Sequence: MSIWVDADACPVVIKDMLYRAARRTNTTLTLVANSFLRVPPSPLIRAIQVPAGFDAADDLIAERVAAGDLVITADIPLAAAVLAKNAQALDPRGNWYTPGTIEERLRMRSMLDQLRGSGVDTGGPSAFSQRDSKSFAGELDRWLSRQRPQPDASAPQSADEPPTE
What are the official names of this protein?
UPF0178 protein Bphyt_5655.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: AOFH_MYCTO
Sequence: MRLTRAVTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGVPADMGGSFIGPTQDAVLALATELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGRLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSSSRNLMAIMTRVTWGCEPDDVSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNAAVRRIDRHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRASGYSGQALSDEAPVFITFDVSPHADGPGILMGFVDARGFDSLPIEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGSWTKYGHWLREPVGPIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL
What are the official names of this protein?
Putative flavin-containing monoamine oxidase AofH.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: Y283_MYCPN
Sequence: MKEKISKKEYNALIRKTGEKHFDGEKEEYGDGTVGLWTYELRKYKLKPPVKVKYVTQEEFGEFKDATNQRLTKIENALVAQGEQIRAQGEQLSQLIKVVLLQGEQIKSQGEQIKS
What are the official names of this protein?
UPF0134 protein MPN_283.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: LUKS_STAAU
Sequence: MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDTKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN
What is the function of this protein?
Leukocidin causes cytotoxic changes in polymorphonuclear leukocytes.
What are the official names of this protein?
Leukocidin-S subunit.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: PCNA2_SULAC
Sequence: MKVKVVDALGFSYIFKTLSQYVSEATLLFGNDGFKVKGMDPSKVVYIDIFVPKDYFEEYNLENEMKIGVSLKDVNEVIKNVSKEDILYLELEKDKIMFTLDGEYLRTFSLPVLSPDEVETPSINLEFPFRANILTSTFGDLLDEFDQIGGDSIRFKAQNGKLYLSVMGDMGESIVELSLENGGLLESTGTDAESLYGLEHVSNTTKMRRPSDTLEIAFGSQLPLKLRYNLPKGGYADFYIAPRSE
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp 2, Proliferating cell nuclear antigen homolog 2, PCNA 2.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: MTLD_STRP7
Sequence: MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEKGKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQRTDIITTAIGPNILPFIAELLAKGIEARRVAGNTQALDVMACKNMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAVDRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVNSGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHKVIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFDYRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIDQIVEYI
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: GATA_VESOH
Sequence: MHTKTIVELYKGLKNKDFSCVELTQYYLSRINQSKLNAFITVTDELALVQAQVADDKIALGNASILTGIPYAHKDIFCTKGVKTSAGSKMLDTFIAPYDATVSQKLNQMNLVMLGKTNMDEFAMGSSNENSFYNAVKNPWNYLKIPGGSSGGSAASVAGGLSCFATGTDTGGSIRQPASLCGITGLKPTYGRISRYGIIAYASSFDQAGIMTKTSQDAAIVLNIMAGFDEKDSTSAEQKVPDYTTNLNNSLQGLIIGLPKEFFLSGLDNEVANNIMFAVKEFESMGAIVKEVSLPNSVYAIPTYYIIASCECSSNLSRLDGVRYGYRSKESKNLEDLYLSSRSEGFGEEVKRRIMIGTYALSTGYYDAYYLKAQKVRRLISNDFKKVFEKVDVIMGPVSPTTAFDLGSVKDPVSMYLADIYTLSVNLAGLPGMSIPVGFAQDLPVGLQLIGNYWSESKLLNIAHQFQLQTDWHLRIPQEC
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: Y080_AFV1Y
Sequence: MSDFPSKQFYNWFKENFGYTRLQRLDKCIDTYGSLENCVKEIMTVAFDDIENEHDSVDELFWGLIKKVMSNKAISSPDNR
What are the official names of this protein?
Uncharacterized protein ORF80.
Protein: SARED_ESCCA
Sequence: MADSSKKLTVLLSGASGLTGSLAFKKLKERSDKFEVRGLVRSEASKQKLGGGDEIFIGDISDPKTLEPAMEGIDALIILTSAIPRMKPTEEFTAEMISGGRSEDVIDASFSGPMPEFYYDEGQYPEQVDWIGQKNQIDTAKKMGVKHIVLVGSMGGCDPDHFLNHMGNGNILIWKRKAEQYLADSGVPYTIIRAGGLDNKAGGVRELLVAKDDVLLPTENGFIARADVAEACVQALEIEEVKNKAFDLGSKPEGVGEATKDFKALFSQVTTPF
What is the function of this protein?
Catalyzes the reduction of benzophenanthridines, preferentially sanguinarine, to the corresponding dihydroalkaloids.  Involved in detoxifying the phytoalexins produced by plant itself.  The sanguinarine produced by intact cells upon elicitation, after excretion and binding to cell wall elements, is rapidly reabsorbed and reduced to the less toxic dihydrosanguinarine.  Can work with both NAD(P) or NAD as a hydrogen donor, but at low concentrations, the reaction velocity with NAD(P)H is threefold higher than with NADH.  However, chelerythrine shows maximum conversion rates with NADH.  The substrate preference is sanguinarine > chelerythrine > chelirubine, macarpine or 10-OH-chelerythrine.  No activity with berberine or phenanthridine cations.
What are the official names of this protein?
Sanguinarine reductase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: YDGT_SALPA
Sequence: MTVQDYLLKFRKISSLESLEKLFDHLNYTLTDDMDIVNMYRAADHRRAELVSGGRLFDVGQVPQSVWRYVQ
What is the function of this protein?
Binds to H-NS and modified the range of genes it silences; H-NS alonge silences core gene while the H-NS-Hha complex (and presumably also H-NS-YdgT) silences genes acquired by horizontal gene transfer.  Plays a role silencing virulence factors in the absence of factors that induce pathogenicity (By similarity).  The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC (By similarity).
What are the official names of this protein?
Transcription modulator YdgT, H-NS/StpA-binding protein 2, OriC-binding nucleoid-associated protein.
What is the protein family that this protein belongs to?
Belongs to the Hha/YmoA/Cnu family.
Protein: PDXH_BORPE
Sequence: MSVSDLRQSYEKGVLVEEQAAASPFQQFARWFDEAVAARVPEPNAMTLATVNAEGQPSARIVLIKGYDDAGFVFFTNYESRKGLDLDANPRASLLFFWQPLERQVRIEGVIEKVSAAESDEYFHSRPLGSRLGAWASRQSQPITRDELEAREREFRDRYGEHPPRPPHWGGYRLKPNRFEFWQGRPSRLHDRLRYEPDGKQGWTIDRLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: MOS_SIBNE
Sequence: SSVNARPCSSPLVCPAKGEKFFGVGSASRIRQLPPRLAWCSIDWDQLCLLHLLGSGGFGSVYKATYHGATVAVKQVKKCSKNHLASRQSFWAELNVACLDHNNVVHIVAASTCTPTSQDSLGTIIMEYAGNCTLHHVIYGIGYLTGNNDGLKRDHEFLSTAQAVVYSCDIVAGLMFLHSQLIVHLDLKPANIF
What are the official names of this protein?
Serine/threonine-protein kinase mos, Oocyte maturation factor mos.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RECO_SOLM1
Sequence: MEYSDQALILAVKRFREIDAWVRLLSPTRGVYTAFAFGGLKSRRRFLGCLDPLNHVQFKVRRSGYRGYHCLAEGKLLDAPRQLRSHPQRLGMAVNCLKFFEAAPVAPGSFAQAYGLMRAMLSTLDAADEPSPLFPLLFRARMTFLHGMLPACGQCAVCGQPLGHDGAVCHVEEGRVACPDCRAAASGGVHARLGGEALALLASAVEQGPEQWAACRPHPAAGREFSRAVDLLVRYHMGLAWEQGGFVRA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: FOLD_ECODH
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: EPL1_YEAST
Sequence: MPTPSNAIEINDGSHKSGRSTRRSGSRSAHDDGLDSFSKGDSGAGASAGSSNSRFRHRKISVKQHLKIYLPNDLKHLDKDELQQREVVEIETGVEKNEEKEVHLHRILQMGSGHTKHKDYIPTPDASMTWNEYDKFYTGSFQETTSYIKFSATVEDCCGTNYNMDERDETFLNEQVNKGSSDILTEDEFEILCSSFEHAIHERQPFLSMDPESILSFEELKPTLIKSDMADFNLRNQLNHEINSHKTHFITQFDPVSQMNTRPLIQLIEKFGSKIYDYWRERKIEVNGYEIFPQLKFERPGEKEEIDPYVCFRRREVRHPRKTRRIDILNSQRLRALHQELKNAKDLALLVAKRENVSLNWINDELKIFDQRVKIKNLKRSLNISGEDDDLINHKRKRPTIVTVEQREAELRKAELKRAAAAAAAAKAKNNKRNNQLEDKSSRLTKQQQQQLLQQQQQQQQNALKTENGKQLANASSSSTSQPITSHVYVKLPSSKIPDIVLEDVDALLNSKEKNARKFVQEKMEKRKIEDADVFFNLTDDPFNPVFDMSLPKNFSTSNVPFASIASSKFQIDRSFYSSHLPEYLKGISDDIRIYDSNGRSRNKDNYNLDTKRIKKTELYDPFQENLEIHSREYPIKFRKRVGRSNIKYVDRMPNFTTSSTKSACSLMDFVDFDSIEKEQYSREGSNDTDSINVYDSKYDEFVRLYDKWKYDSPQNEYGIKFSDEPARLNQISNDTQVIRFGTMLGTKSYEQLREATIKYRRDYITRLKQKHIQHLQQQQQQQQQQQQQAQQQKQKSQNNNSNSSNSLKKLNDSLINSEAKQNSSITQKNSS
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
What are the official names of this protein?
Enhancer of polycomb-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the enhancer of polycomb family.
What are the subcellular locations of this protein?
Nucleus.