PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_GEOSL
Sequence: MKIDTIRNFSIIAHIDHGKSTLADRLLEYTGALTEREMQDQFLDKMDLERERGITIKAQTVRLTYRADDGNDYILNLIDTPGHVDFTYEVSRSLAACEGALLVVDASQGVEAQTLANVYLAIDNNLEVFPVLNKIDLPAAEPERVKHEIEEIIGLDAHDAVMASAKEGIGTREILEEIVKKIPPPEGDPAAPLKALLFDSWYDQYQGVIILVRVIDGTVKKGDKIQLVSTGRSYEALKVGVFAPVMREVPQLAAGEVGFLIAGIKDVADAKIGDTVTHALKPCVTPLGGFKEVKPMVFSGLYPIDTAQYEQLRDALAKLKLNDSSFSFEPETSLALGFGFRCGFLGLLHMEIIQERLEREFNLDLITTAPTVVYKVHRIKGDVITIESANQLPPLQEIDYIEEPFILASIHTPNEFVGGILSLCEEKRGVQREIKYLTPTRVMIIYELPLNEVVLDFYDRLKSITKGYASLDYEHLNYRRSDLVRMNILINGEAVDALSLIIHRDKAYYRGRDLVSKMKELIPRQMFEVVIQAAIGAKVIARETVKALRKDVLAKCYGGDITRKRKLLEKQKEGKKRMKNVGNVELPQEAFLAILKVEEK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KAD_BORPE
Sequence: MRLILLGPPGAGKGTQAAFLTQHYGIPQISTGDMLRAAVKAGTPLGLEAKKVMDAGGLVSDDLIIGLVRDRLTQPDCANGYLFDGFPRTIPQADALKSAGIALDYVVEIEVPESDIIERMSERRVHPASGRSYHVRFNPPKAEGVDDVTGEPLVQRDDDREETVRHRLNVYQNQTRPLVDYYSSWAQSDAAAAPKYRKISGVGSVDEIKSRLSQALQS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NR0B1_CALJA
Sequence: MAGEDHQWQGSILYNMLMSAKQRHAAPEAPEARLGDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEARLGPCWGCSCGSDPGVGREGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSAKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEGLPGRRAMALLYRCCFCGEDQPQQGSTLYSMPTSTNQTPAAPEERPGAPWWDTSCGALRPVALKNPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWAPLLMLELAQDHLQFETVEVSEPSMLQKILTTRRRETGGTEPLPVPTLQPHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHIRMTHRGHHDRFIELNSALFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKL
What is the function of this protein?
Orphan nuclear receptor.  Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis.  Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions.  May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 0 group B member 1, Nuclear receptor DAX-1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR0 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus (By similarity).
Protein: MTRE_METFE
Sequence: MDPAVASLGILALTTASAIIGQTIEDVETNIGSQSNPNSQVQLAPQMGNLHRFFNKAIAGEPFAYCTFCGVSGAITVATLYLHLPAVIALAIGAAITTLIWLAYSTTAYLGRVSGSATFNQPVFLDMLTENLGPIAGHAFIVFFCMTGVAYLMTLPVKGFAHPFPIPVIGMIWGMTIGAIGSAVGDVYYGAEAEFVHKKFGGGIPVASHGDITRKGVLGARSPMEVGNFTVKYGSPITGMAFGLIVLSITRGVYNIE
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit E, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E.
What is the protein family that this protein belongs to?
Belongs to the MtrE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNLJ_BORAP
Sequence: MSSKIQQEIADLKKLIRKWDKEYYVDSLPSVEDFVYDKHILRLQELESKCPEYKTLDSPTLKFGSDLLNDFKEVEHSVPVLSLDKVYNLDLLKSWIDKIDFSNSFNISVEPKIDGCSIVLYYKDGILEKALTRGNGKFGNDVTKNIRTIRHVPLFLGEKVDLVLRGEVYITKENFLKINKFLEKPYTNSRNLASGILRRVDSREVANFPLNIFIYDFLNAGLDFKTNNLAIEKLKKLGFKVNPLIRFFDQKSSIKEVLNYIADITKKRNSFEYEIDGVVLKVSDFALREKLGYTLHHPKWAMAYKFEALSGFSKVNSIVVQVGRSGKITPVANIDKVFVSGAFITNATLHNQDYITSINLNVGDIVKVSRRGDVIPAVEMVINKFSTGFFKVPDKCPSCKTVVVKEGAHFFCTNNNCPSVAVERIKYFCSKNCMDIEGFSDKTISFLFEKKFISSEIDLYTFNFYKLLKFKGFKDRKINNLINSIEASKKKPFSKLLLSIGIKELGENTIRLLFLNNLNSFSKLFRLCQDRDFAFLTLLKIKGIGEKIALNIIDAFNNSIMINKFKVFENLGFKMEERILIDDENKLLVGKKFCITGSFNGYSRPIVIDKLENKGAIFKTCVTKGLDFLVVGEKAGTKLKKALNLNVKIMSFEDIKSYLD
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: UVRC_GEOSL
Sequence: MFDTKRLTTLPDAPGVYLMKGNGGDILYVGKAKSLRKRVRSYFSKGGESRYHIRFLVGRVADIDVIVTDTEKEALLLENTLIKEHRPRYNLDLRDDKTYFSLRLDMNEEFPRLTIVRRPGRDGARYFGPYSSASAAREVLKQLYKLFPLRHYPLESCRRRRRPCLFYQLRQCAAPCHGLISGEDYQSLAEGAALFLAGKNSDLTRLYRQRMAAAAADERYEDAARYRDLIRAIEVTVEKQKMVAGDGDTDVVGFFRDATDLSVSILFYRGGRLMGSRNYLLDWEMDDAEGLSSFLSGYYNRDVVIPDEILIPFTVDDTDPLGELLTERRGKKTVLRHPVRGTKAELVRLAARNAEAYLHEKREKDSGMEQVLGELKEKLHLTNLPRRIECYDISTIQGRYSVGSRVRFQNGAPDKAGYRRYRIRTVPGTDDFAMMHEVLSRRFRDGHGGDGRPDLIVIDGGMGQLNVLTAILEELGLHGIDAVSLAKSRVERNMSDNEVVRSDERVFLPGRRNPVVLRQNGAPLLLLARIRDEAHRFAITYHQKLRGKGSIRSSLEGIPGIGEKRKRELLKRFGSIRALRQADREQLAAVPSVSPALADAIWKALHGEEPEAP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_VIBVU
Sequence: MNPKSNPDTIFSAPIDKIGDFTFDERVAEVFPDMIQRSVPGYSNIISAIGMLAERFVKPHSNVYDLGCSLGAATLSMRRHIKQEGCQIIAVDNSKAMVERCKLHVNAYRSDTPVNVIEADIRHIDIENASVVVLNFTLQFLSPEDRYVLLEKIYAGLRPGGILILSEKYVFEDQVSNELLIDLHHDFKRANGYSELEISQKRSAIENVMRPDSKKQHKERFAQIGFSSYDVWFQCFNFGSMFAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: CYSH_ECO5E
Sequence: MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKNGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLK_CAEBR
Sequence: MPSSTLLELAPNTHSKCKFETRNRSSSSSSGCSSSSTELYDLAAAHAALISRQQQILNQGIPIIPEHQLAAAAVAHHHHQLHPSVQHQLVAGHHHHHLPQVAHHPAILPRSDVIQQPSHFALHQHLQNLVQQQQQQQALHHHQQLVGDMALVSHTHPAAVGSTTCYEKNPQKQQQVPQIPTQPQVAHVSSNAILAAAQPFYQPPVQDSQPDRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLDILQPANPSFFQEFTSWHLTPSIHHQRLISHIKPICLFFVLPLVSLLCAHMYVCMWWHGTALLEGRKETITYVLTELMQSDLHKIIVSPQTLTIDHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDSRDRLNMTHEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGPRAPNLQSLYRLSQQTTDDAVDLLVKLLKFNPDERISVEEALSHPYLEEGRLRFHSCMCSCCYTKANVPSRIFSQELDPKHESPFDPKWEKDMSRLSMFELREKMYQFVMDRPALYGVALCINPQSAAYKNFASSSVAQASELPPSPQAW
What is the function of this protein?
Has a role in the Wnt signaling pathway controlling the asymmetry of cell divisions during embryogenesis (By similarity).  Operates in the AB and EMS cell lineages influencing cell specification (By similarity).  Required for body wall muscle development, endoderm development, pop-1 asymmetry and T-cell division asymmetry (By similarity).  Component of the beta-catenin-lit-1 complex which promotes the phosphorylation, down-regulation and subcellular relocation of pop-1 (By similarity).  Regulates plp-1 nuclear localization in embryos (By similarity).  Plays a role in male tail tip morphogenesis (By similarity).
What are the official names of this protein?
Serine/threonine kinase NLK, Loss of intestine protein 1, Nemo-like kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Nucleus. Note=Located in the anterior cell cortex before and during asymmetric cell division. After division, located preferentially in the nucleus of the posterior daughter cell (By similarity). Localizes to the nucleus in hyp9 and hyp10 cells prior to male tail tip morphogenesis (By similarity).
Protein: HSLO_ECO8A
Sequence: MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_RHORT
Sequence: MKHLDSLEAESIHILRETAAQFRKPVLMYSIGKDSSVLLHLARKAFYPSRPPFPFLHIDTTWKFHEMIAFRDKRVAEEGVDLIVHTNRAGVEAGVSPFTHGAAYTDIMKTQALREALTQGGFDGVIGGARRDEEKSRAKERVFSFRDAHHRWDPKNQRPELWNTYNGRVGKGESVRVFPLSNWTELDIWLYILRESIPVVPLYLAKPRPVVERDGALIMVDDNRLPLEPGETPQTRWVRFRTLGCYPLTGAIESRAASLPEIIAEMLVARTSERQGRLIDQDQAASMEMKKQEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: FUR_BRUAB
Sequence: MNKPYTKPDYEQELRRAGVRITRPRRIILNILNETEDHPDALEIFRRAVEEDDSISLSTVYRTMKLLEERGAIHRHAFAGGPSRFEQASGAHHDHIIDMDSGDVVEFHSDKIEKLQEEIARSLGFEIVHHRLELYCKKLKS
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPR_ECOLI
Sequence: MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELAEQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQIPNGSTLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFISQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDAPPPVSVMQVLTDHHIQLELC
What is the function of this protein?
Repressor of the glycerol-3-phosphate regulon.
What are the official names of this protein?
Glycerol-3-phosphate regulon repressor.
Protein: AMIF_BACHK
Sequence: MGSSGSMVKPISGFLTALIQYPVPVVESRADIDKQIKQIIKTIHSTKAGYPGLELIVFPEYSTQGLNTKKWTTEEFLCTVPGPETDLFAEACKESEVYGVFSIMERNPDGGEPYNTAIIIDPQGEMILKYRKLNPWVPVEPWKAGDLGLPVCDGPGGSKLAVCICHDGMFPEVAREAAYKGANVLIRISGYSTQVSEQWMLTNRSNAWQNLMYTLSVNLAGYDGVFYYFGEGQVCNFDGTTLVQGHRNPWEIVTAEVYPELADQARLGWGLENNIYNLGSRGYVATPGGVKENPYTFVKDLAEGKYKVPWEDEIKVKDGTIYGYPVKKTIHS
What is the function of this protein?
Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.
What are the official names of this protein?
Formamidase, Formamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: RASF8_HUMAN
Sequence: MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIEREAPFQSGSLKRPGSSRQLPSNLRILQNPISSGFNPEGIYV
What are the official names of this protein?
Ras association domain-containing protein 8, Carcinoma-associated protein HOJ-1.
Protein: AROK_CLOBM
Sequence: MENIILIGMPLSGKSTLGRELSKILKYDLIDTDTLIEEMEDKSIKEIFKIYGEDYFREKELKIINKLKKESNKVISTGGGLPIYNKNIYELKKIGFTVYLKVPLEELIKRMVKKEDDARPLLKNDDTKFLEEMYKNRIEIYEKAHTIICNTNYEESLIAIVKAYKKWKGI
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSC1_MOUSE
Sequence: MAVACAAPGSTFSKQLLFFLLVLVLFCDACQKVSLHVPSHLKAETPVGKVNLEECLKSPSLILSSDPAFRILEDGTIYTTHDLLLSSEKRGFSILLSDGQGQEQKKLEVVLSAREKKVFRKRHTKEPVHNRSKRRWAPIPCSLMENSLGPFPQHIQQIQSDAAQNYTIFYSISGPGVDKEPYNLFYIEKDTGDIYCTRSIDREQYDQFLVYGYATTADGYAPDYPLPLLFKVEDDNDNAPYFETKLTVFSVPENCRSGTSVGQVTAIDKDEPGTLHTRLKYKILQQIPDQPKHFSIHPDTGVITTTTPLLDREKCDTYKLVMEVRDMGGQPFGLFTTGTITISLEDENDNSPYFTQTSYTTEVEENRIDVEILRMVVHDQDLPNTPHSKAVYTILKGNENGNFKITTDPNTNEGVLCVVKPLNYEVSRQVTLQIGVLNEAQFTNAANAQPPTMCTTTVTVKIKDRDEGPECQPPVKVIQSKDGLPAGQELLGYKAVDPETSSGEGLRYEMVGDEDNWFEINKITGDLRTVKVLDRESKFVKNNQYNISVVATDTAGRSCTGTLVVLLEDFNDHPPQIDKEVTICQQEKDFAVLEPIDLDGPDNGPPFQFLLDNSSSKLWTLESQDGKRAILRQRHNLNYNYYSVPIQIQDRHGFSAKHVLSVRVCDCTTPTECRMAVKEERDAKPNIILGKWAILAMVLGSALLLCILFTCFCVTTTKRTVKKCFPDDVAQQNLIVSNTEGPGEEVTEANIRLPTQTANICDTSMSVGTLGGQGIKTQQSFEMVKGGHTLESHKGGVLGAAEPGRYAYTDWQTFTQPRLGEKVYLCGQAEEHKHCEDYVRPYNYEGKGSMAGSVGCCSDRQEEEGLEFLDQLEPKFRTLAKTCVKK
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.  May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.  Linked to the keratinization of epithelial tissues.
What are the official names of this protein?
Desmocollin-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: RSMG_LISMH
Sequence: MNPEQFQTALAEKGIELSDTQLKQFHDYFEMLVEWNEKMNLTAITDEKEVYLKHFYDSISAAFYVDFTKFDTICDVGAGAGFPSLPIKICFPHLKVSIVDSLKKRMTFLDALAEKLGLTDVHFYHDRAEIFGQNKAHREKYDLVTARAVARMSVLSELCMPLVKKGGSFLVMKAAQAEQELQTAEKAIKLFGGKVEEHFAFSLPVEESERNIYVITKTKETPNKYPRKPGTPNKLPIE
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_ANAMM
Sequence: MMSKGVLVGVVTDARRDKTVKVSVYRMVHHKVYKKIVKKCRIYSVHDEHNRCKRGDVVKIREHIPVSATKRWIVVDS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RL10_HALVD
Sequence: MSESEVRQTEVIPQWKREEVDELVDFIESYESVGVVGVAGIPSRQLQSMRRELHGSAAVRMSRNTLVNRALDEVNDGFEELKEYIAGQVALIGTNDNPFALFKELEASKTPAPINAGEVAPNDIVIPEGDTGVDPGPFVGELQQVGASARIMDGSIMVTEDSNVLSEGEEVSEELANVLAELGIEPKEVGLDLRGVFSEGVLFEPDELAIDVDEYRADIQSAVSAATNLSVNAVYPTAQTAPTLIAKATSEAKAVGLFANIESPDFMPELISKADAQLRALAANIDDEEALPEELRGVSAADTGAAEEEESTDEEAADADQADAAEDDDAADDDGDDEDAGDALGSLF
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog, L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: I5P1_RAT
Sequence: MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVLHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYKKVTGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGVRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVVLQLEKKLFDYFNQDVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDSSQGEQYMNTRCPAWCDRILMSLSAKELVLKSESEEKVATYDHIGPNVCMGDHKPVFLAFRIAPGAGKPHAHVHKCCVVQ
What is the function of this protein?
Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate (PubMed:8626616).  Plays a crucial role in the survival of cerebellar Purkinje cells (By similarity).
What are the official names of this protein?
Inositol polyphosphate-5-phosphatase A, Type I inositol 1,4,5-trisphosphate 5-phosphatase, 5PTase.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cell projection, dendrite.
Protein: YIDD_SHESA
Sequence: MAQTQSPLQWLATTFIRGYQIFISPLLGPRCRFNPTCSHYAIEAIKVHGTAKGCWFALKRILKCHPLHPGGSDPVPPKNDRCNK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CHM2B_XENTR
Sequence: MASLFKKKTVDDIIREQNKELRGTQRAITRDRAALEKQEKQLEMEIKKMAKAGNKDACRVLAKQLVQLRKQKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDASDDEEESQDIVNQVLDEIGIEISGKMAKAPSAAKGLPSTSASKSSGISDEEIERQLKALGVD
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 2b, Chromatin-modifying protein 2b, CHMP2b.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein.
Protein: EVI5_MOUSE
Sequence: MVTTKMTAAFRNPNRRQVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSASLHTTSSSTTLSTPTQSPSSPSKLSPDDLELLAKLEEQNRLIETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWDDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCNAQSMTIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRELVTVRAVLSSLDCCCMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEYLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGGPEKLIQSAYQVKYNSKKMKKLEKEYTTIKTKEMEEQGEIKRLRTENRLLKQRIETLEKHKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKKNNSFPDENNIARLQEELIAVKLREAEAIMGLKELRQQVRTLEEHWQRHLARTSGRWKDPPKKNAVNELQDELMSIRLREAETQAEIREMKQRMMEMETQNQINSNQLRRAEQEVNSLQEKVCSLSVKNKGLLAQLSEAKRRQAEIECKNKEEVMAVRLREADSIAAVAELQQHIAELEIQKEEGKLQGQLNRSDSNQYIRELKDQIAELTHELRCLKGQRDFSSRPPFDGIHIVSHLIGDDELFHSSDEDFIDSSLQESAIGFPLHRKSGPMSLNPALADGSESEAEDGMLGPQESDPEAPQKQPPQRESYSTTV
What is the function of this protein?
Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase.  May play a role in cytokinesis (By similarity).
What are the official names of this protein?
Ecotropic viral integration site 5 protein, EVI-5.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associates with the mitotic spindle through anaphase and remains within the midzone and midbody until completion of cytokinesis.
Protein: RSMC_ACTPJ
Sequence: MLSLESEVLTRHLPLFANKSILLFGDVRDRFADQIKANAKSVAVFSSYFDYARQYADVSFGLYCEIKAELAVFYWTKNKQECQYQLLQWLSQVDVGQEMLIIGENRAGVRSVEKLLEPYGNIAKIDSARRCGLYHFELQSVPDFDGKKFWKSYRLQDLNIFALPAVFSSAELDGGTQLLLSTFNKADRLKGKVLDLGCGAGVIGASLKQQFEKIKLTMSDIHAMALESSRHTLAENALDGTVVASDVFSNIEERFDLIVSNPPFHDGIDTAYRAVEDLIAQAKQRLNRGGELRIVANAFLPYPDLLDKAFGSHQVIAKSNKFKVYSAKA
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.