PharMolix/UniProtQA huggingface dataset:
Protein: HSP7E_XENTR
Sequence: MAAIGVHLGCTCACVAVYKDGRADVVANDAGDRVTPAVVGFLEKETIVGLAAKQSRVRNATNTIVKVKQILGRSYGDPHTQKHISESKCIVVEKVGKPKYEIDTGETQKFVSSEDVAKLIFSKMKETAQSALGSDVNDVVITVPFDFGESQKKALGEAATAAGFSILRMIHEPSAALLAYGIGQESPTGKSNVLVYKLGGTSLSVTVIEVNSGIYRVLATSTYDDIGGICFTEALAQHLASEFQRTYKQDIRGNARAMMKLMNSADVAKHALSTLGSSNCFVDSLYDGIDFDCNVSRARFELICSSLFNQCIDPIKKLLEQIGFKANDVNQVVLCGGSARIPKLQQLIKDLFPEVEMLSSIPPDEVIPVGAAIQAGILIGKENLSTDLDTITIECSASDILVKETDESGDNKFTVLLPSGTPLPARRQHVLQAPGHISSVCLELYESGGKSPVESKFAQIVLKDLQKKASGVHDILTVLTMKRDGSLHITCTDKDSGKSEMITVEETP
What is the function of this protein?
Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state.
What are the official names of this protein?
Heat shock 70 kDa protein 14.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GO_HCMVM
Sequence: MGKKEMIMVKGIPKIMLLISITFLLLSLINCNVLVNSRGTRRSWPYTVLSYRGKEILKKQKEDILKRLMSTSSDGYRFLMYPSQQKFHAIVISMDKFPQDYILAGPIRNDSITHMWFDFYSTQLRKPAKYVYSEYNHTAHKITLRPPPCGTVPSMNCLSEMLNVSKRNDTGEKGCGNFTTFNPMFFNVPRWNTKLYIGSNKVNVDSQTIYFLGLTALLLRYAQRNCTRSFYLVNAMSRNLFRVPKYINGTKLKNTMRKLKRKQALVKEQPQKKNKKSQSTTTPYLSYTTSTAFNVTTNVTYSATAAVTRVATSTTGYRPDSNFMKSIMATQLRDLATWVYTTLRYRNEPFCKPDRNRTAVSEFMKNTHVLIRNETPYTIYGTLDMSSLYYNETMSVENETASDNNETTPTSPSTRFQRTFIDPLWDYLDSLLFLDKIRNFSLQLPAYGNLTPPEHRRAANLSTLNSLWWWSQ
What is the function of this protein?
Plays a role in viral entry into host cells.  Forms a trimeric complex at the surface of the viral envelope together with gH and gL.  This complex is required for entry in host fibroblasts (PubMed:28403202).  Mechanistically, engages host receptor(s) including PDGFRA to mediate infection (PubMed:28403202).
What are the official names of this protein?
Envelope glycoprotein O.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U47 family.
What are the subcellular locations of this protein?
Virion membrane. Note=Host membrane associated, either via its interaction with gH, or as a type II transmembrane protein.
Protein: COXX_STAAN
Sequence: MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLFGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGAVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAA_BRUAB
Sequence: MWEKVDQLTPSRYSPYRFFSAQEWAAFRADTPLTLTYEEVKRLRSLGDPIDLDEVRRIYLSLSRLLYAHVEASQLLFRQRQQFLNMEESYKTPFIIGVAGSVAVGKSTMARILKELLARWPSSPKVDLVTTDGFLYPNAVLREQNMMERKGFPESYDIGAVLRFLSAIKAGMSRVRAPLYSHLSYDVLPGEYQIVDKPDILIFEGINVLQVRDLPEDGKMVPFVSDFFDFSIYIDADPRLIHKWYIDRFMRLRETAFRDPQSFFHRYSQLSQEAARSIAEGLWQNINMKNLNENILPTRPRADLILRKGSDHLIEEVALRKI
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY_STAAM
Sequence: MIQTLVNFFRTKEVRNKIFFTLAMLVIFKIGTYIPAPGVNPAAFDNPQGSQGATELLNTFGGGALKRFSIFAMGIVPYITASIVMQLLQMDIVPKFSEWAKQGEVGRRKLNNVTRYLAISLAFIQSIGMAFQFNNYLKGALIINQSIMSYLLIALVLTAGTAFLIWLGDQITQFGVGNGISIIIFAGILSTLPASLIQFGQTAFVGQEDTSLAWLKVLGLLVSLILLTVGAIYVLEAVRKIPIQYAKKQTAQRLGSQATYLPLKVNSAGVIPVIFAMAFFLLPRTLTLFYPDKEWAQNIANAANPSSNVGMVVYIVLIILFTYFYAFVQVNPEKMADNLKKQGSYVPGIRPGEQTKKYITKVLYRLTFVGSIFLAVISILPILATKFMGLPQSIQIGGTSLLIVIGVAIETMKSLEAQVSQKEYKGFGGR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRD_STRCO
Sequence: MYKTFFKLVFSRMDPERAHHLAFRWIRLAVRVPVLRTFVAAALAPRHKELRTEALGLRMHGPFGLAAGFDKNAVAIDGMAMLGFDHVEIGTVTGEPQPGNPKKRLFRLVADRALINRMGFNNDGSLAVAARLASRTPVFRTVVGVNIGKTKVVPEEEAVGDYVKSAERLAPHADYLVVNVSSPNTPGLRNLQATEALRPLLSAVREAADRAVTARRVPLLVKIAPDLADEDVDAVADLAVELGLDGIIATNTTIAREGLGLTSSPALVGETGGLSGAPLKARSLEVLRRLYARVGDRITLVGVGGVETAEDAWERILAGATLVQGYSAFIYEGPFWGRAMHKGLAARLRQSPYATLADAVGADVRKHS
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL25_PARL1
Sequence: MAETQTLKAEAREKGSKGAVRSLRRAGRVPAVIYGDKQSPELIAVSYKDVSALYQTGTFMSHVLDVEIGGKTERVIPRDVQFEPVRDFIIHVDFLRLGKNATVTVDVPVHFHNHEASPGIKAGGVLNIVRHEVELVCPADAIPEQLDIDLTGFEMGSSIHISAVKLPAKVSPTITDRDFTIATIAAPAAVVSADNEAKTEEAGEDKSEEKSSGKED
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: Y1420_STACT
Sequence: MHAFLVILFMIVIGALIGGITNIIAIKMLFHPQRAYHIGKWRIPFTPGLVPKRREEIAYKIGNVIEEHLITESLIKEKISSLSAREAIESFITQQIQKLKKDNATLQNFAGYFGIDLAKTAEDKLSNLIDEKLAQYYQDHNQEPLKSLIPSELEVELDEKIEALTPLLCDRARIYLSSAKGEQDIYNMLDTFFAEKGKIIGLLQMFMTKENIAERIQMELIRLTNHPKAREIVAQLINNEYMTLKNKSLGGVVSPEQFNNIKEKFTPLILSYADISARVNQPIKDLAPSIVKYAEQHAATWTTNLIVEKAAEHLSSIMKQVNLSGIVEEQINSFDLDYIERLIIEIANKELKLIMLLGFLLGGIIGCLQGIIALFV
What are the official names of this protein?
UPF0754 membrane protein Sca_1420.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HOSM_YARLI
Sequence: MCATDNAPAANAAPEKPSNVGVEVGHTGEQTNPYGANPADFLSNVSKFQLIESTLREGEQFASAFFDTETKIEIAKALDDFGVDYIELTSPAASEQSRSDCEAICKLGLKAKILTHIRCHMDDARLAVSTGVDGVDVVIGTSQFLRQYSHGKDMNYIAQSAVEVIEFVKSHGIEIRFSSEDSFRSDLVDLLNIYRTVDKIGVNRVGIADTVGCANPRQVYELVRTLKSVVSCDIECHFHNDTGCAIANAYTALEAGANLIDVSVLGIGERNGITSLGGLMARMIAADRDYVLSKYKLHKLRDLENLVADAVQVNIPFNNPITGFCAFTHKAGIHAKAILANPSTYEILNPADFGLTRYIHFANRLTGWNAIKSRVDQLNLHLTDAQCKDVTAKIKKLGDVRSLNIDDVDSIIREFHADVTSTPTVAATEGPAVEDEPAAKKAKTEE
What is the function of this protein?
Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate.  Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.
What are the official names of this protein?
Homocitrate synthase, mitochondrial, HCS.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL3_STAEQ
Sequence: MTKGILGRKIGMTQVFGENGELIPVTVVEASQNVVLQKKTEEVDGYNAIQVGFEDKQAYKKGSKSNKYANKPAEGHAKKADTAPKRFIREFRNLNVDEYEVGQEVSVDTFETGDIIDVTGVSKGKGFQGAIKRHGQGRGPMAHGSHFHRAPGSVGMASDASKVFKGQKMPGRMGGNTVTVQNLEVVQVDTENSVILVKGNVPGPKKGLVEITTSIKKGNK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ATP61_ARATH
Sequence: MRRIFLFDENSLNSSSTIDTSSASTIDTSFASQCTNFSSGQASGTQDTHAGIFEDCPGLNPNDERVVELQCEIREKCEALTQDPEMGLILGEALHAESDNVPFLQSIADDLTQNGVSGEAFQEALNIVGQAAASPLDQFEIVPLIPMHIGNFYFSFTNSSLFMLLTLSFFLLLIHFVTKKGGGNLVPNAWQSLVELLYDFVLNLVKEQIGGLSGNVKQMFFPCILVTFLFLLFCNLQGMIPYSFTVTSHFLITLALSFSIFIGITIVGFQRHGLHFFSFLLPAGVPLPLAPFLVLLELISYCFRALSLGIRLFANMMAGHSLVKILSGFAWTMLCMNDIFYFIGALGPLFIVLALTGLELGVAILQAYVFTILICIYLNDAINLH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane (By similarity).
What are the official names of this protein?
ATP synthase subunit a-1, F-ATPase protein 6, P6-1.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FIS_SHIF8
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: METK_THEM4
Sequence: MRRLFTSESVTEGHPDKVADQISDAILDAMLEQDPRSRVAVETLVTTGIAIVSGEVTTRAYVDIQDIVRKTIMEIGYTRAKYGFDGETCAVLSSIHSQSPDIAMGVDKALEAKEGELNAQDDLELVGAGDQGMMFGYATNETKELMPLPIMLAHKLALKLSEIRKSGTVPFLRPDGKTQVTVEYDENDRPVRVDTVLISTQHEPNVTIAEIKEALVKYVIDPIIPEELRDDNLNILVNPTGRFVLGGPSADTGLTGRKIIVDTYGGAIPHGGGAFSGKDPTKVDRSAHYFARYVAKNVVAAGLADKFMIQVAYAIGKAKPVSVMINTYGTAKIDEDKILKAVLELFDFRPGAIIKKLNLLRPIYKKTAAYGHFGRELEEFTWEKLDMVDELKRLL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_CAMJD
Sequence: MAITVYYDKDCDLNLIQSKKVAIIGFGSQGHAHAMNLRDNGVNVIIGLREGSVSAVKAKNAGFEVMSASEASKMADVIMILAPDEIQADIFNVEIKPNLSEGKAIAFAHGFNIHYGQIVVPKGVDVIMIAPKAPGHTVRNEFTLGGGTPCLIAIHQDESKNAKNLALSYASAIGGGRTGIIETTFKAETETDLFGEQAVLCGGLSALIQAGFETLVEAGYEPEMAYFECLHEMKLIVDLIYQGGIADMRYSISNTAEYGDYITGSKIITEETKKAMKGVLKDIQNGVFAKDFILERRAGFARMHAERKNMNDSLIEKTGRNLRAMMPWISAKKLVDKDKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: TF2LX_PANPA
Sequence: MEAAADGPAETQSPVQKDSPAKTQSPAQDTSIMSRNNADTGRVLALPEHKKKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRILPDMLQQHRNDPIIGHKTGKGAHATHLQSTEASVPAKSGPSGPDNVQSLPLWPLPKGQMSREKQPDPESAPSQKLTGIAQPKKKVKVSITSPSSPELVSPEEYADFSSFLLLVDAAVQRAAELELEKKQEPNP
What is the function of this protein?
May have a transcription role in testis.
What are the official names of this protein?
Homeobox protein TGIF2LX, TGF-beta-induced transcription factor 2-like protein, TGFB-induced factor 2-like protein, X-linked, TGIF-like on the X.
What is the protein family that this protein belongs to?
Belongs to the TALE/TGIF homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_CHLTA
Sequence: MTTESLETLVEQLSGLTVLELSQLKKLLEEKWDVTAAAPVVAVAGAAAAGDAPASAEPTEFAVILEDVPSDKKIGVLKVVREVTGLALKEAKEMTEGLPKTVKEKTSKSDAEDTVKKLQEAGAKAVAKGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CLPX_HYPNA
Sequence: MTKPNGSGDSKNTLYCSFCGKSQHEVKKLIAGPTVFICDECVELCMDIIREENKTSAIKSRDGVPTPQEICDVLDDYVIGQRYAKRILSVAVHNHYKRLSHAGKTDGVELSKSNILLVGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIVLKLLQSADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVAAVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLEKIIAARGENASIGFGATIKSGEERGVGDTLREVEPEDLQKFGLIPEFIGRLPVLATLEDLDEKALIQILTQPKNALLKQYQRLFDMESVQLTFTPEALVAVARRAITRKTGARGLRSIMESILLDTMFELPNLRGVEEVVINAEVVDGNAEPLYVHASKSQTEAG
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ERYC_BRUA2
Sequence: MALTLSLNTNPLVNRFAEPDDLIETVARDLRLRDLQLTHEFINPSWQASTIRRLTRDMDRALQRTGVRVTSGMTGPYGRLNHFGHPDRDVRRYYVDWFKTFADIIGDLGGKSVGTQFAIFTYKDFDDPARREELIKIAIDCWAEVAEHAAGAGLDYVFWEPMSIGREFGETIAECMKLQDRLTAANMAIPMWMMADIDHGDVTSANPDDYDPYAWARTVPKVSPIIHIKQSLMDKGGHRPFTAAFNAKGRIQPEPLLKAFAEGGAVDNEICLELSFKEREPNDREVIPQIAESVAFWAPHIDTGAKDLKI
What is the function of this protein?
Catalyzes the racemization of D-erythrulose 1-phosphate to L-erythrulose 1-phosphate.
What are the official names of this protein?
D-erythrulose 1-phosphate 3-epimerase, 3-tetrulose-4-phosphate racemase.
Protein: RL23_CHLPN
Sequence: MKDPYDVIKRHYVTEKAKMLEHLSAGTGEGKKKGSFCKDPKFVFIVSHDATKPLIAQALEAIYVDKNVKVKSVNTINVKPQPARMFRGRRKGKTSGFKKAIVTFYQGHSVG
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: UVRB_MANSM
Sequence: MSHKINSKPFILHSEFKPSGDQPQAIEILAENLNDGLAHQTLLGVTGSGKTFTIANVIAKLNRPAMLLAPNKTLAAQLYAEMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDPDSYLKMMLHLQTGAIIDQRQILVRLAELQYTRNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGTGFGAVPRFTVYPKTHYVTPREQILDAIEKIKSELADRREYFIKENKLLEEQRITQRTQFDIEMMNELGYCSGIENYSRYLSGRNEGEPPPTLFDYMPSDALLVIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEFERLAPQTIYVSATPGPYELEKSGTEIIDQVVRPTGLLDPEIEIRPVSIQVDDLLSEARQRADRNERVLVTTLTKRMAEDLTDYLDEHGIRVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLKGKAILYADRITNSMEKAITETNRRREKQMKYNEEHGITPQGLNKKVGELLDIGQGGSNKSRNKPRSQKAAEPATTYAIPMTAKEYQQQIKKLEQQMYKFAQDLEFEKAAAIRDQLHKLREQFVENG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIK_YARLI
Sequence: MDRLNNLATQLEQNPAKGLDAITSKNPDDVVITAAYRTAHTKGGKGLFKDTSSSELLASLLEGLVKESKIDPKLIGDVVCGNVLAAGAGATEHRAACLVAGIPETVPFVALNRQCSSGLMAVNDVANKIRAGQIDIGIGCGVESMSNQYGPNSVTPFSNKFQNNEEAKKCLIPMGITSENVAAKYNVSRKAQDAFAAKSYEKAAAAQAAGKFDQEILPIKTTVLDDDDNEKEVTVNKDDGIRPGVTAEKLGKLKPAFSAEGTTHAGNASQISDGAGAVLLMRRSVAEKLGQPILAKFVHCKTVGVPPELMGIGPAYAIPAVLEDLGLTVNDVDVFEINEAFASQALFSIQHCGIDESKVNPRGGAIAIGHPLGATGARQFATLLSELKESGKKVGVTSMCIGTGMGAASLVVAE
What is the function of this protein?
Responsible for the thiolytic cleavage of straight chain 3-keto fatty acyl-CoAs (3-oxoacyl-CoAs).
What are the official names of this protein?
3-ketoacyl-CoA thiolase, peroxisomal, Acetyl-CoA acyltransferase, Beta-ketothiolase, Peroxisomal 3-oxoacyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: GMHA_MAGSA
Sequence: MKFATFLDQQIAEHAETLAVTGAAVREPFQRLVQACVDSLAAGGKILFFGNGGSAADAQHLAAELVIRYRYNRKALAALALTTDTSTLTACANDFSYEEIFSRQIEALGRPGDVAIGITTSGSSPNVLTALAVARDMGLVAAGFAGRDGGKMVGLADPLLIVPSNVTARIQEMHILIGHALCDQVEAVAAPA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_HAES1
Sequence: MQSYDIAQFIDHTALTAEKTEQDILDLCNEAIEHNFFSVCINSGYIPLARQKLQNTNVKICTVVGFPLGANLSTVKAFEAKEAIKAGATEIDMVINIGWIKSNQWESVKADIQAVLAACEGALLKVILETCLLTKEEIITACKICRELGVGFVKTSTGFNKGGATVENIALMRQVVGENIGVKASGGVRDTKTAIEMIKNGATRIGSSSGIAIINGLTDNNAIY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBACT_RHOIS
Sequence: MNATQTQPQNADQQSVAATAKEQGTEARDRQPPLHPETPAPSNTPRKDSLNQFASWLRQDARAEATTYLHRANTHHDGE
What is the function of this protein?
May function as a protein modifier covalently attached to lysine residues of substrate proteins.  As this bacterium does not seem to encode proteasome subunits and proteasome ATPase adjacently to UBact, this tagging system may serve another role than targeting the modified proteins for degradation by proteasomes.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein UBact.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-like protein UBact family.
Protein: BHCC_PARDE
Sequence: MNAKTDFSGYEVGYDIPALPGMDESEIQTPCLILDLDALERNIRKMGDYAKAHGMRHRSHGKMHKSVDVQKLQESLGGSVGVCCQKVSEAEAFARGGIKDVLVTNEVREPAKIDRLARLPKTGATVTVCVDDVQNIADLSAAAQKHGTELGIFVEIDCGAGRCGVTTKEAVVEIAKAAAAAPNLTFKGIQAYQGRDAAHGQLRGPQGQAGRRHCPGERGRGRAGGRGLAPEFVSGGGTGSYYFESNSGIYNELQCGSYAFMDADYGRIHDAEGKRIDQGEWENALFILTSVMSHAKPHLAVVDAGLKAQSVDSGLPFVYGRDDVKYIKCSDEHGVVEDKDGVLKVNDKLRLVPGHCDPTCNVHDWYVGVRNGKVETVWPVSARGKGY
What is the function of this protein?
Catalyzes the condensation of glyoxylate and glycine into (2R,3S)-beta-hydroxyaspartate ((3S)-3-hydroxy-D-aspartate).  Functions in glyoxylate assimilation via the beta-hydroxyaspartate cycle (BHAC) (By similarity).  In vitro catalyzes the cleavage of both D-erythro- and D-threo-3-hydroxyaspartate to glycine and glyoxylate.  Also acts on D-threonine, D-3-phenylserine and D-3-3,4-methylenedioxyphenylserine (PubMed:12835921).
What are the official names of this protein?
3-hydroxy-D-aspartate aldolase, D-3-hydroxyaspartate aldolase, D-HAA.
What is the protein family that this protein belongs to?
Belongs to the DSD1 family.
Protein: HSLV_SALPC
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELGAREIAEKALDIAGDICIYTNHFHTIEELTAKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y005_SYNY3
Sequence: MSPAPMPVTTAEQDRDVVVIDAVVEEVRPPRLPKSHLEDLGPVSDMFPESWEYHPDLIMEFYRKRPLQVLGRLINILFPLLRFILGIWWEKLRGKDPTVSRAKAIQLRELLTNLGPTYIKVGQALSTRPDLVPPVFLDELTTLQDQLPSFPNEVAYRFIEEELGAPAEEIYAELSPEPIAAASLGQVYKGKLKTGEAVAVKVQRPDLVRRITLDIYIMRSLSLWARRSVKRLRSDLVAITDELASRVFEEMNYYQEAINGEKFAQLYGSLPEIYVPSIYWQYTGRRVLTMEWVEGIKLTNIKAIQAQGIDATHLVEVGVQCSLRQLLEHGFFHADPHPGNLLAMADGRLAYLDFGMMSTIQPYQRYGLIEAVVHLVNRDFDSLAKDYVKLDFLKPDTDLKPIIPALGQVFGNALGASVAELNFKSITDQMSAMMYEFPFRVPAYYALIIRSMVTLEGIAIGIDPNFKVLSKAYPYIAKRLLTDQSEELRTSLKELLFKEGSFRWNRLENLLRNAKNSPGFDFDYVLNEATEFLLSDRGQFIRDRLVAELVNSIDQLGRNTWQQVSHNIQERISFLGDLGNGNGKAHQTKTIKVVPQPAIAQQEETWQHLQNLWQILKETPGFDPLKFVPVLSQIIVNPTSRRMGQQVAEGLLQKAIARVIRQWALALESQPNPAIKIRNAA
What are the official names of this protein?
Uncharacterized protein sll0005.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
Protein: PRX2C_ORYSJ
Sequence: MAPVAVGDTLPDGQLGWFDGEDKLQQVSVHGLAAGKKVVLFGVPGAFTPTCSNQHVPGFINQAEQLKAKGVDDILLVSVNDPFVMKAWAKSYPENKHVKFLADGLGTYTKALGLELDLSEKGLGIRSRRFALLADNLKVTVANIEEGGQFTISGAEEILKAL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin-2C, Glutaredoxin-dependent peroxiredoxin, Peroxiredoxin IIC, Thioredoxin peroxidase 2C.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.