PharMolix/UniProtQA huggingface dataset:
Protein: RBFA_LACGA
Sequence: MKHRIGRVEGEILRELTKILRKDIRDPRLSDITITAVECTNDLSYATIYYSLLTEDPAKEKEVAEGLDKAKGMMRHLLGQTLTVYKVPELIFKRDTSVAYGSKIDNLINQVKKQDQERENKNK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_AFIC5
Sequence: MPTINQLIAKPRVLQKSRKKVPALQQSPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVIGYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHILRGVLDTQGVKNRKQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DAPA_KOSOT
Sequence: MFRGAASAVITPFKGNEIDYDSFDKFLKFQLDSGINGLIVLGTTGEAPTVTSEERREIISFAVKKVGGRVPVIIGTGSNSTAHSIELSQEAFELGADGVLVVTPYYNKPTQEGLYRHYEAIAKSVPGHVIIYNVPGRTGIDIIPETVLRCAQIENIVGIKEASGNQAQVDELLRLKAKVRPEFKIWSGNDDQAFHLVCSGGDGVISVLSNVAPSQTVEMIAAALEGDLEKAREIHLKLFPLMKALFIETNPIPVKFATHLLGFGSETLRLPLTEASKRTREVVKKAMQDCGVLR
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_POLAQ
Sequence: MKASQSFLATLKEAPSDAEVVSHKLMVRAGLIRKISAGIYNYLPLGLKVIRKVENIIREEMNRAGAIELLMPMIQPAELWQETGRWEKMGPELLRIKDRHDRDFLIQPTSEEVITDLARNEIRSYKQLPVNFYQIQTKFRDERRPRFGIMRGREFSMKDAYSFDRDTEGLKKSYQTMFEAYTQIFKRMGLEFRAVTADNGAIGGSGSQEFHVIADTGEDAIVYCPSSDYAANLEAAESLALNATRGAATQTMAKVPTPDKTNCADVAKLLNLPLEQTVKSLLFAADQESGPAKLFMLLVRGDHELNEVKASKVPGMTESRFATETEIKQACNAPAGYLGPVGVSAEVTIVADRTVANMADFVCGANDAGHHLTGVNWGRDLPEPLVLDIRNAVIGDPSPDGKGVVDICRGIEVGHVFQLGTRYSEAMGCTYLDQQGKAQPMVMGCYGIGVTRLLGAAIEQGHDERGIIWPISMAPVEVVICPMGYEKSEPVKAACDQLHDELVAAGIDVILDDRNERPGAMFADWELIGAPFRVVIGDRGLADSQVEFKGRTDADSQNIPLAQIKEKVISAVQAAKNAVA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_STRPD
Sequence: MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVIPANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKACEYEFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHIESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKILLPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: AMPN_HELAM
Sequence: GMYTHEGSDP
What is the function of this protein?
Acts as a receptor for B. thuringiensis Cry1Ac delta-endotoxin.
What are the official names of this protein?
Aminopeptidase N, AP-N, CryIA(C) receptor.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
Protein: ATPD_CLOK1
Sequence: MYEYLDRRYALALYKIAEEKGKVEEYLEELKDVTDIINNDTQFLEFIEHPEISTAEKKKTFINVFKGKISEDILSFLLILIDKGRINQLYSKLKEMGKIYLENHNTVIATVKTVIPLEDDERETLTEKLRRKFNKEVLIKEELDPEIIGGVYVEVNNMVIDGTVKSKLSEMKKIMLKGEQR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GLMM2_SHESR
Sequence: MSRKYFGTDGVRGKVGTFPITPDFAMKLGWAAGTVLASTGTKEVLIGKDTRISGYMLESAMEAGFSAAGVNVALIGPMPTPAVAYLASTFRADAGVVISASHNPFYDNGIKFFSNTGTKLNDAQELEIEALLEQALEHNALQCVASEKLGKVRRIDDAAGRYIEFCKGTFPNHLSLAGLKIVVDSAHGAAYHIAPNVYRELGAEVISINDKPNGVNINDHCGATHLDSLQSAVMIHEADLGIALDGDADRVMFVDHNGHVVDGDEILFILAQAAYQKGEMQGGVVGTLMSNLGLELALKQMGIPFLRAKVGDRYVVEQLKETGWQLGGEGSGHILSLQHASTGDGIVASLQVLKAILESGKRLAELKAGMTKLPQVLINVRLTSGSADSILSKDSVKQAVITAEEVLGNQGRVLLRKSGTEPLIRVMVESTDISLTQQQAEYIAQAVKVA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase 2.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ALG9_SCHPO
Sequence: MPSKAPRKSLSVSFVWTFSILAVLRLTSASFRVIDDCDEVYNYWEPLHYLLYGYGLQTWEYSPEYAIRSWFYIALHAVPGFLARGLGLSRLHVFYFIRGVLACFSAFCETNLILAVARNFNRAVALHLTSVLFVNSGMWSASTSFLPSSFAMNMVTLALSAQLSPPSTKRTVKVVSFITIGAVIGWPFSAALSIPFILLELVDLKGRFRHLFCRWFKAIFVALLITGICITVDSLFYHRIQFVAWNIVKYNVLAKDGRGPDIYGTEPWWYYFANLSLQHNIVLWFAMACGPLVLLAAFTNWINLDSFLDLSSVISPFYIWLFIFIIQPHKEERFMYPIYPVLCLAAAIGLDMSLKLMIQILSSINETVRSKFPVRFVVLCVYAIIGCLSIARILAIQNYNAPMIIYPAISFLETDNNVTTNVCVGKEWYRYPSTFFLPDNSRLKFVKSEFDGILPGEFVESNSTWWNREGYYQIPEHMNEFNNEEPTRYTSLESCDFLIDLEFDHSKATVNEPIYSKSDGWIPVMVYPFIDTKQTPFMGRAFAVPFIEPKWGRYEILVKKPVKIDFSNLRRASKQQA
What is the function of this protein?
Catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides.
What are the official names of this protein?
Alpha-1,2-mannosyltransferase alg9, Asparagine-linked glycosylation protein 9, Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PAPA2_MYCTA
Sequence: MFSITTLRDWTPDPGSIICWHASPTAKAKARQAPISEVPPSYQQAQHLRRYRDHVARGLDMSRLMIFTWDLPGRCNIRAMNYAINAHLRRHDTYHSWFEFDNAEHIVRHTIADPADIEVVQAEHQNMTSAELRHHIATPQPLQWDCFLFGIIQSDDHFTFYASIAHLCVDPMIVGVLFIEIHMMYSALVGGDPPIELPPAGRYDDHCVRQYADTAALTLDSARVRRWVEFAANNDGTLPHFPLPLGDLSVPHTGKLLTETLMDEQQGERFEAACVAAGARFSGGVFACAALAERELTNCETFDVVTTTDTRRTPTELRTTGWFTGLVPITVPVASGLFDSAARVAQISFDSGKDLATVPFDRVLELARPETGLRPPRPGNFVMSFLDASIAPLSTVANSDLNFRIYDEGRVSHQVSMWVNRYQHQTTVTVLFPDNPIASESVANYIAAMKSIYIRTADGTLATLKPGT
What is the function of this protein?
Catalyzes the acylation of trehalose-2-sulfate by adding the palmitoyl group at the 2'-position to yield the intermediate trehalose-2-sulfate-2'-palmitate (SL659).
What are the official names of this protein?
Trehalose-2-sulfate acyltransferase PapA2, 2-O-sulfo trehalose long-chain-acyltransferase, Polyketide synthase-associated protein A2.
What is the protein family that this protein belongs to?
Belongs to the PapA acyltransferase family.
Protein: COX2_BRALA
Sequence: MATPAQLGLMDAASPVMEEMIYFHDHVMLVLILITCLIFYSMLVLISSKYIYRFLTDGHVIETVWTVIPAIILVVVALPSLKLLYLTDELDNPQLTIKSVGHQWYWSYEYTDYYDIEFDSYMLPLGDLSKGDARLLEVDNRVVLPVDTSVRVLVTAADVIHSWTVPSLGLKMDAVPGRLNQLALQCSRVGTFYGQCSEICGANHSFMPIVIEAVPVEVFEGWCDMMLDEESLGSLNMKR
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARGC_BRASB
Sequence: MSIRVGIVGISGFGGGEAMRLVAGHPSFELVYAAGEGSAGQRLAERFPGVPAKLADLVIEKWDPARLPSLDVLFASLPTGASRDALARVPDDVKIVDIGGDHRYADGWTYGLADVWPQEIASKTRIANPGCFPAAALTPLAPLLADKLISPDTIVIDAKTGISGAGRGGGTGFGYAESNENLIPYGLLRHVHMPEIERSIARISGGSATGLVFTPHLVPMTRGILATIYARGRATTAQCLDAARRFYEGSAFVRVTDKPPQTKWAAGSNLAFVSYAADPERNLVIALGVVDNLGKGAAGQAVQNANLMCGLPETAGLEGAPVWP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHP_THIDL
Sequence: MLTYTGTVINVQTFAAKPDP
What are the official names of this protein?
Chemoheterotroph-specific protein.
Protein: ATPG_SYNE7
Sequence: MANLKAIRDRIKSVRNTRKITEAMRLVAAAKVRRAQEQVLSTRPFADRLAQVLAGLQQRLQFENVDLPLLQRREVKTVALLVVSGDRGLCGGYNSNVIRRAEQRARELSAQGLDYKFVIVGRKAGQYFQRREQPIEATYSGLEQIPTAQEANDIADELLSLFLSGTVDRVELVYTKFLSLVASNPVVQTLLPLDPQGLASSDDEIFRLTTRGGSFTVEREKLTSEVAPLPRDMIFEQDPAQILSALLPLYLSNQLLRALQEAAASELAARMTAMNSASDNANALVGQLTLVYNKARQAAITQELLEVVAGAEALNG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: ISPF_CHLMU
Sequence: MSEPSSCFVLPDPEWIYRVGIGQDSHRFLPSDNPKPCVLGGIIFENTPGFEANSDGDVVFHAICNAFSSVTHQVILGALADELLKAKGISDSAVYLKEAVASLKPTQKISHLAITIEGQRPKLLPKISAMREKIAEILRISLDSVNITATSGEGLTSMGQGHGVQCFCVLTVMEFCPR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: OLF8_CHICK
Sequence: VAICNPLLYTISMPKSLCMKLVAGSYLGGVLNSLTQTCCLLPLPFCGPNVINHYFCDTNPLLKLTCSDGRLNELLLVTFNGTISMTVLLIIVISYVYILVSILSIRSARGRHKAFSTCASHLLTVTLFYVPAGLSHMQPGSKYSLDMEKVTAVFYTLLV
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor-like protein COR8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASPA_CORGL
Sequence: MSKTSNKSSADSKNDAKAEDIVNGENQIATNESQSSDSAAVSERVVEPKTTVQKKFRIESDLLGELQIPSHAYYGVHTLRAVDNFQISRTTINHVPDFIRGMVQVKKAAALANRRLHTLPAQKAEAIVWACDQILIEERCMDQFPIDVFQGGAGTSLNMNTNEVVANLALEFLGHEKGEYHILHPMDDVNMSQSTNDSYPTGFRLGIYAGLQTLIAEIDELQVAFRHKGNEFVDIIKMGRTQLQDAVPMSLGEEFRAFAHNLAEEQTVLREAANRLLEVNLGATAIGTGVNTPAGYRHQVVAALSEVTGLELKSARDLIEATSDTGAYVHAHSAIKRAAMKLSKICNDLRLLSSGPRAGLNEINLPPRQAGSSIMPAKVNPVIPEVVNQVCFKVFGNDLTVTMAAEAGQLQLNVMEPVIGESLFQSLRILGNAAKTLREKCVVGITANADVCRAYVDNSIGIITYLNPFLGHDIGDQIGKEAAETGRPVRELILEKKLMDEKTLEAVLSKENLMHPMFRGRLYLEN
What are the official names of this protein?
Aspartate ammonia-lyase, Aspartase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.
Protein: CUE_DROME
Sequence: MIRIRFGMDVLLVLLLATCLLTPAHGTPLEWDFAVTLRTKIQFMDSSWQTIATAAHEFDELSALTFDESEELIYFNDLKHRNGSIFSLKRDLIAANHVAEQTIARTGNESVGGLAYDPLNMNLFWSDTEQRKIFFAPIHGSATPQVLVDLSAEGGRPDGVAVDVCRRKLYWTNSNVTHPTVERINLDGSNRTVIISSNIDMPRGIVVDQLSDRLFWIDDLKGVFFSVESSKLDGSDRQVVLKDKHHEPLNLAVTNDAIYWTDRTTRAVWSHPKVPVIKVTTTSKPDEEDSTDSTDFKDPEPVAEDCPLVRVANLSEEARGIVARTGFYQRLQKDHHCASIVRKVKERVDEQSRKFEIRSLLDQKIKVLEDERCMNDGEYRAATDLCICPTGFKGSRCEIRECHNYCVHGTCQMSELAYPKCYCQPGFKGERCELSVCSGLCLNGGHCRVSKDENEAPSCECPAKFGGARCEQNSTEICSLFCRLLKHEPEMYVPFGCHSICEELAQDNSTNIAIPQYQHLEVCLTPRVWTSSVIIILVVGIVSSLLLVAVIVQGIRRLYKPKRPRIRKTFVVRKQARTNSAGDTPLTNRPLATEQCEITIENCCNMNICETPCFDPKLVEQTLSKSSCKEDKKILIHNMEDDLY
What is the function of this protein?
Has a role in spermatogenesis and oogenesis (PubMed:8244010).  Might have a role in triglyceride homeostasis (PubMed:25409104).  Probably by regulating lipid storage and catabolism, plays a role in neuronal function (PubMed:25409104).
What are the official names of this protein?
Protein cueball.
What is the protein family that this protein belongs to?
Belongs to the cueball family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PSA3_DICDI
Sequence: MSSVGSGYDLYVSTYSPDGKLFQVDYANKAVENSGTLVAIKAKDGVVLGVEKLVPSKMLCSGSNRRVHHIDTHVGVAIAGFLADARQLITRARSEAKNYKSTYGQPIPIKVLSQRIASYNHMHTLYGSVRPFGCSIAITGIDQYGPQLFLVEPSGSCVGYFGASLGKGKQAAKNELEKIKFSEMTCREAIKEVSRIIYSVHDEVKDKDFELELGWISTETNNVHQIVPKELHDEAEAYAKQSLEDANM
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UREE_YEREN
Sequence: MILIEHILGNVKKDPVWQEKLKDATFDLLVLDQREAQKSRCRKLSTQGLDLGISLDRHVVLADGDVLAWDEKTNVAVVVQINLRDVMVIDLSELKSRSPDELIKTCFELGHALGNQHWKAVTKNNEVYVPLTVATTMMDSVMRTHGFQHLPFRFVKGAEILPLLSNSEARLLFGGAEDTDTHVHVASPLDEPHGSGLHVHAIHSHGTGHTHSHDHDHSHSHGDHDHDHKH
What is the function of this protein?
Expression of the urease operon increases the likelihood of bacterial survival by contibuting to acid resistance in vitro and in vivo in BALB/c mice.  Y. enterocolitica enters the body via an oral path and must survive the acidic stomach before being able to colonize the intestinal mucosa (PubMed:7558281).
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA2_CLOBM
Sequence: MINNKPIIGIPIGDPAGVGPEIVVKSLTEAEVYEKCNPILIGDAKVIKQAMGFCNVNLNINSIKKADEGKFTLGTIDLIDLNNIDIDELKIGKVQGIAGKAAFEYIKKSVEMAKEGELDAIATTPINKESLREGNVNYIGHTEILADLTDTEDPLTMFEVRGMRVFFLTRHVSLRKACDLVTKERVLDYIIRCSEALEKLGVKDGKMAVAGLNPHSGEHGLFGDEEMKAVVPAIEEAQKMGYKVEGPIGADSVFHLALKGRYNSVLSLYHDQGHIATKTLDFERTIAVTNGMPILRTSVDHGTAFDIAGTGQASSVSMVEAIILAAKYSPKFKK
What is the function of this protein?
Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).
What are the official names of this protein?
Putative D-threonate 4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family. PdxA2 subfamily.
Protein: NH2L1_DICDI
Sequence: MADSSNNEKAKPLADSKLTLTILDLIQQSNNLGQLKKGANECTKAVSRSTAEFVVLAADAEPLEILLHIPLLCEDKNIPYVFVSSKSELGRACDVSRPVVACAVTVDDKSQLKSQITNVKDSLDRLWIV
What is the function of this protein?
Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly.  The protein undergoes a conformational change upon RNA-binding (By similarity).
What are the official names of this protein?
NHP2-like protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ATG14_KLULA
Sequence: MIHCGICGSPKIPNVEFLCAHCINGSPSILLRDKLKLLLLRQEVEQLKHDVGEQLEAGFAGNGQFGKQLQKLDVYNEKRRLIKLRQRVQLVKNKIDVKRNRYQELERYLKDEDHFDKDKKVFDVEEIVNDEALTMSKLSQVLQRKQTALFKELCQWFRIEKCDEDVNNNNNVSAYTIWGVPMINLKYSNEMDRDKQVISMRYIHQFINFSFNIWLFEGISDVSIENEQNVIQNYSQLIYDTLRLLQVRKLVSESVSIRDILIRYDLDGMIYYLSKSKYLSSLDDASNSYPPTLQNIKQLVASMIPSI
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I.  This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure.  ATG14 mediates the specific binding of the VPS34 PI3-kinase complex I to the preautophagosomal structure (PAS) (By similarity).
What are the official names of this protein?
Autophagy-related protein 14.
What is the protein family that this protein belongs to?
Belongs to the ATG14 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: EGLA_EMENI
Sequence: MRSLVLLSSVLALVAPSKGAFTWLGTNEAGAEFGEGSYPGELGTEYIWPDLGTIGTLRNEGMNIFRVAFSMERLVPDSLAGPVADEYFQDLVETVNGITALGAYAVLDPHNYGRYYGNIITSTDDFAAFWTILATEFASNELVIFDTNNEYHTMDQSLVLNLNQAAIDAIRASGATSQYIFAEGNSWTGAWTWVDVNDNMKALTDPQDKLIYEMHQYLDSDGSGTNTACVSSTIGSERVTAATNWLRENGKLGVLGEFAGANNQVCKDAVADLLEYLEENSDVWLGALWWAAGPWWGDYMFNMEPTSGIAYQEYSEILQPYFVGSQ
What is the function of this protein?
Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan.  Involved in the degradation of complex natural cellulosic substrates.
What are the official names of this protein?
Endo-beta-1,4-glucanase A, Endoglucanase A, Carboxymethylcellulase A, Cellulase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: COQ7_AZOSB
Sequence: MFDKAIIEFDKALRTVFAPARSVRPVPGDDVPDAPLDDEQKRHAAALMRVNHVGEICAQALYQGQAIMSGDERVREELQRASHEETEHLAWTEQRIAELGGRKSLLNPLWYGGALAIGMLAGRFGDRWNLGFLAETERQVEAHLTSHLERLPADDRKSRAIVEQMRTDEVEHAETALKLGGRELPLPVRSAMKLASRVMTTAAYRV
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HRCA_MYCS5
Sequence: MKQLKKQHEEILKAVVGAYLTQKNEISSALLVKNYGIKFSPAKVRYLMTALEDEGLLVKETKSSGRKPTNKGLEYYAKFLSNAFDLKLINNLEKIFLNRKDNIYNTIEEVTKELASLTGATFVTKFKDPNLILKSINLFEVSESLATIILVVSNGEVLSRKIDIPENKAIKISDLKIAMNIFQDNLIDCKLIDLEKRILLLKDILAEKIIQYEDVIESYVKSILGIGIKSQIYGRENIILSRKIAREDVNEILNILEKNSIWDALEKNSNDFEEIRISINSKGAFFSKRIDENNNLTEISVVAPNESDSNSIKSGIMLLTKIITNNINEKEKDKNERKHS
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: CCME_CERS5
Sequence: MKGLKKKRRIQIITLAFVALAGSTALIGYAMRDGINFFRSPTQVVEAPPSETEVFRIGGLVEKGSLVRGQGETVTFRVTDTNATVPVRFTGVLPDLFAEDAGMVGTGRLVDGVFQASEILAKHDETYMPKEVVDALKEQGVFQHTEDQPQG
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: AEN_HUMAN
Sequence: MVPREAPESAQCLCPSLTIPNAKDVLRKRHKRRSRQHQRFMARKALLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQCLRAGSGSAPCSRRPAPGKASGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIADYRTRWSGITRQHMRKAVPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWEQQEARSLWTCPEDREPDSSTDMEQYMEDQYWPDDLAHGSRGGAREAQDRRN
What is the function of this protein?
Exonuclease with activity against single- and double-stranded DNA and RNA.  Mediates p53-induced apoptosis.  When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.
What are the official names of this protein?
Apoptosis-enhancing nuclease, Interferon-stimulated 20 kDa exonuclease-like 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction.