PharMolix/UniProtQA huggingface dataset:
Protein: MURD_BURP6
Sequence: MFGDRQRPMVLVLGLGESGLAIARWCARHGCRLRVADTRETPPNLAALTAAGVDFEFVGGAFSPALVDGGIELVALSPGLSPLAEDLAPLVAAARERGIPVWGELEFFAQALAALGANGYAPKVIAITGTNGKTTTTSLAGLLCERAGKKVAVAGNISPAMLDKLTEAIDAAALPDVWVLELSSFQLDTAHTFAPDAATILNITQDHLDWHGGFAAYAAAKGRVFGPRTVRVLNRDDAEVMRFAPPAAAADAPRAVTFGLNEPAADGDYGLLRENGIAWLVEAIDRDAADAPAAPSRRRKQEAANPPDIALKRLMPADALRIRGLHNAANALAAYALARAIGLPAAPLLHGLREYRGEPHRVEVIATLDGVDYVDDSKGTNVGATVAALDGLAQRAVLIAGGDGKGQDFEPLAAPVARWCRAVMLIGRDAPALREALADTGVPLADHATLEAAVRAASALAQPGDAVLLSPACASLDMFRNYAHRADVFRSAVEDIALEKGTTL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_CERS4
Sequence: MAVGVFDSGLGGLTVLDAVQRRLPEVPFVYFGDNAHAPYGVRDADDIFHLTCAATERLWAEGCDLVILACNTASAAALKRMQETWIPKDKRVLGVFVPLIEALTERQWGDNSPPREVAVKHVALFATPATVASRAFQRELAFRAIGVDVEAQPCGGVVDAIEQGDEILAEALVRSHVEALKRRMPHPQAAILGCTHYPLMEPIFQEALGPEVSVYSQANLVAESLADYLARKPEFAGDGTESKFLTTGDPRSVSNKATQFLRRRITFEAA
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: SAA_NOTEU
Sequence: MKLLTSLFLLSLVLCVNSQGWLRDSLDFLNQARLGAGDMWRAYRDMREANFKNSDKYFHARGNYDAAKRGPGGVWAAEVLSDAREFLQGGSSGRGVEDSMADQEANRWGRSGKDPNRYRPKGLDPKY
What is the function of this protein?
Major acute phase reactant.  Apolipoprotein of the HDL complex.
What are the official names of this protein?
Serum amyloid A protein, SAA.
What is the protein family that this protein belongs to?
Belongs to the SAA family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCNA_NANEQ
Sequence: MRVTFPDAKALKKIVPIVADLISEGQFVATEEGIKLVAMDPASIAMVIWEMKPEAFIDYTIEGDKEIITVSMDDLKTIVKKLKQREMVVWETDREKNKLKILARGTIKKTFSIPLLEGEETETPIPSLEYNNVVELDSKAIKEIIDDASAIADSLKFKAEPPSKLIIKAEGEMKEMTVELTEGEDAVVSIDIQEEAYASYSIDYLKKFAKAADVSDIAILKLKTDYPLWLEYRYLDKMTLIFILAPRSD
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: Y2548_ALTMD
Sequence: MIVSTTPTLEGHKIDAYYGIVVGEAVMGANVFKDLFASIRDIVGGRSGSYEEELTTARKLAFTELEHEARSMGANAVVGIDLDYQVIGDKGSMLMVSISGTAVKTSPL
What are the official names of this protein?
UPF0145 protein MADE_1007770.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: KAD2_YEAS7
Sequence: MSSSESIRMVLIGPPGAGKGTQAPNLQERFHAAHLATGDMLRSQIAKGTQLGLEAKKIMDQGGLVSDDIMVNMIKDELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQGTPLEKAIELKVDDELLVARITGRLIHPASGRSYHKIFNPPKEDMKDDVTGEALVQRSDDNADALKKRLAAYHAQTEPIVDFYKKTGIWAGVDASQPPATVWADILNKLGKN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: YHE5_YEAST
Sequence: MKMLLFLNEACIFIDSVCEGIVFWGLCLFVCAECGNAYYRGARVPYKTLFRAFEVSVFGQKEYPNFRFGPSYRFLCLSPYSICCKQPPMEEVILYYPSPDSLIKNRKRVLGVAYL
What are the official names of this protein?
Putative UPF0377 protein YHL045W.
What is the protein family that this protein belongs to?
Belongs to the UPF0377 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PILR3_ARATH
Sequence: MEEEKKKSRVLIIGATGRLGNYLTRFSIESGHPTFALIRNTTLSDKLKSLSDAGVTLLKGSLEDEGSLAEAVSKVDVVISAIPSKHVLDQKLLVRVIKQAGSIKRFIPAEYGANPDKTQVSDLDHDFYSKKSEIRHMIESEGIPYTYICCGLFMRVLLPSLVQPGLQSPPTDKVTVFGDGNVKAVFVNDVDVAAFTIKTIDDPRTLNKTLYLSPPGNICSMNDLVELWEGKIEKKLEKTFATENQLLKKIKETPYPDNMEMVFIYSVFIKGDHTYFDIESCGGVNGTELYPDVKYMTVSEFLDTLL
What is the function of this protein?
Probable reductase that might be involved in the reduction of lariciresinol into secoisolariciresinol.  In most plant species, a single enzyme is able to reduce both pinoresinol and lariciresinol efficiently while in Arabidopsis, PRR1 and PRR2 show a strict substrate selectivity for pinoresinol.
What are the official names of this protein?
Probable pinoresinol-lariciresinol reductase 3, AtPLR3, lariciresinol reductase.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: MLTF_PECAS
Sequence: MKPLKLNYFFIGIITLLLALALWPSIPWRSSQDVQLRQILSRGELRISTVNSPLTYAMSNGSPTGLDYELAKRFADYLGVKLVVSSRKNLDELFDDLDGDDADLLAAGLIYNHERLERFRAGPTYYSISQQMVYRLGSPRPKTLDKLQGRLVVTSGSAHAATLRDLKAEKYPQLSWESASDQSTQELLKQVADGKLDYTLGDSVTIGLMQRIHPQLAVAFDLSDEEPVIWYMRRSHDDSLSAALLDFFSQLVEDGTLARLEEKYLGHVGEFDYVDTTTFLSAIDETLPDLRPLFEKYATDIDWKLLAAISYQESHWNPLATSPTGVRGLMMLTRNTAESLNVTDRVDPEQSIRGGAQYMSHMMQKMPDTIPEDEKIWFALASYNMGYAHLLDARKLTEKQKGNPDSWVDVKMRLPMLSQKRYYTQTTYGYARGHEAYNYVENIRRYMVSLEGYLIEKEAKVQQQTQIALGYPAVPLTKVPE
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: CMCB_CONRE
Sequence: LCCPPQXCGPDCASPCC
What are the official names of this protein?
Conotoxin Reg12b, Reg12l.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEC_PSEAB
Sequence: MNQKKAVILLSGGLDSATVVAMAKADGYACYTMSFDYGQRHRAELQAAERVARQLGVIEHKVIGLDLNGMGGSALTDESIAVPESPSEGIPVTYVPARNTVFLSLALGWAEVLDARDIFIGVNAVDYSGYPDCRPEFVEAFERMANLATKAGVEGNGFRIQAPLQYLSKAQIIQAGVARGVDYGLTVSCYQADEQGRACGKCDSCRLRADGFAAAGISDPTPYF
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: LGI1_MOUSE
Sequence: MESESSRRMGNACIPLKRIAYFLCLFSVVLLTEGKKPAKPKCPAVCTCSKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNAFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSPKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIDTQLYVIVAQLFGGSHIYKRDGFANKFIKIQDIEVLKIRKPNDIETFKIEDNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIARPPLALRTPHLILSSSSQRPVIYQWSKATQLFTNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA
What is the function of this protein?
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1.  It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit.  Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors.  Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity).
What are the official names of this protein?
Leucine-rich glioma-inactivated protein 1.
What are the subcellular locations of this protein?
Secreted. Synapse. Note=Isoform 1 and isoform 2 are detected in the cytosolic and microsomal fractions respectively.
Protein: SIAH3_HUMAN
Sequence: MLFFTQCFGAVLDLIHLRFQHYKAKRVFSAAGQLVCVVNPTHNLKYVSSRRAVTQSAPEQGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHANPVTPCLCMCPLFSCQWEGRLEVVVPHLRQIHRVDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQERHEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLVLNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM
What is the function of this protein?
Negative regulator of PRKN translocation to damaged mitochondria.  Acts probably by destabilizing PINK1 protein, hence inhibiting PRKN targeting to dysfunctional depolarized mitochondria.
What are the official names of this protein?
Seven in absentia homolog 3, Siah-3.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL36_ICTPU
Sequence: MAIRYPMAVGLKKGHPVTKNVTKPKHSRRGGRLTKHSKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNILAAMRKAAAKKE
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL36 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Note=Detected on cytosolic polysomes.
Protein: NACA_BABDI
Sequence: MAEPVEDSVDEISSEGDSDVEESKGPEGSAPKNRQDKNERKSRKLLGKLGMKPVDGVTKVCIKKSKQIYFVVNKPDVYKLPNSDTYVIFGEAKVEDMSQNSALEAAQRLSQLSSALQAVGADRGTDSSAAAHASGHDHAHDHDHSHGDCASKADESSVNQSDIDLVVSQVGCTREQAVEALIKNKGDIVETIMQLST
What is the function of this protein?
May promote appropriate targeting of ribosome-nascent polypeptide complexes.
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
Protein: Y410_MYCPN
Sequence: MKEKIPFYNEKEFNEMMKKTKKGTFSGWYIINPENNSVEFSGSFNRQFKLNKPIIPVNTEYVTRKEFNEYKDSNDQRLIKIETTLTAQGEQINKLTQTVEKQGEQIRELQVEQKAQGEQIKAQGETLKLILQTLQKMSDRLDKIDPPK
What are the official names of this protein?
UPF0134 protein MPN_410.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: SLAI1_XENTR
Sequence: MAEVKCSSSTGSPTTNGLVANAELEVKKLQELVRKLEKQNEQLRNRASAVSNCTPSPHLLLQHPPSVVHQSGTCILSSPVLTRPAGLCLPSPVPTLLCTSAVAGSLFSPESMGCFSTNKRLHLSCINAAEGPQNDCPVPGSTLLDEVQVLDLEDGYCSGDEDTWLYVSPTKDQRTFDSSVSPLQWCRQVLDHPSPEIEAAKRSLCFRLEQGYTVKTSHLSPQSSVDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDFATTSTCSSVSRPRSSFSLYSGKKLSCSSDQDSDRYSVEEDDEDFDHLPPPQPRLSRCSPLQRGLSHSQTFSSIRDCRKSPSSQFLNGYQQYNYSSQPQTTEQSQSRTNADKLRRSMPNLARMPSTNNNPVVSMTTVRNSQSFDSNLHGAANGVSRMQSSIPSPGQLQQRVHSVGHFPVSVRPPLKATAYVSPTVQGGSGIPSSTSLQSLSSSGIPMPNKTTSAATIGRSALPRPALSTANGSSIPRSKIAQPQRSFLQPPKTLASLSTLRDGNWRDGCY
What is the function of this protein?
Microtubule plus-end tracking protein that might be involved in the regulation of cytoplasmic microtubule dynamics, microtubule organization and microtubule elongation.
What are the official names of this protein?
SLAIN motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SLAIN motif-containing family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. Detected at the plus end of growing microtubules.
Protein: ITR3_SPIOL
Sequence: EDKCSPSGAICSGFGPPEQCCSGACVPHPILRIFVCQ
What is the function of this protein?
Trypsin inhibitor.
What are the official names of this protein?
Trypsin inhibitor 3, SOTI III, Trypsin inhibitor III.
What is the protein family that this protein belongs to?
Belongs to the Mirabilis serine proteinase inhibitor family.
Protein: RS15_CHLPM
Sequence: MSLSKEFKEEIITKFGGTDKNTGKAEVQVALFSNRISDLTGHLQKHPKDKHSRRGLLMLVSKRKKALKYLQNVAIDRYRQVIADLDLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SSRP_DESHD
Sequence: MASEGIKVISDNRKAYHDYFVEEKLEAGVILTGTEIKSIRNGRVNLKDSYARIENGEVWLYQLHISPYEQGNRFNHDPLRKRKLLLNRSEIIKLVGKVQQQGLTLIPTKIYLKRGLAKIELGVCRGKKNYDKRQDIAERDAKREIERHFRDQGKGY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MTFA_ECOSE
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAERFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHRTNDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PON2_MELGA
Sequence: MGKVLAAALIGIAAALAAERLLAFRNRLNATREVDPVALPNCRLIKGIEAGSEDIDILPNGLAFISSGLKYPGLKSLAPDKPGEIFLMDLNEKKPKASELRISRGFDLGSFNPHGISTYIDKDDTVYLFVVNHPHQKSTVELFKFMEEDNSLLHLKTIRHDLLTSVNDVVAVGPDSFYATNDHYFYDFILMFLEMYLGLTWSNVVYYSPKEVKEVAAGFYSANGINISPDKKYIYIADIFDHNVHVMEKHADWNLTHVKTLQLDTLADNLSVDPDTGDIWTGCHPNGMKLFYNDPDNPPASEVLRIQNILAEQPTVTRVYAENGSVLQGTSVATVYNRKLLIGTVYHRALYCEL
What is the function of this protein?
The absence of paraoxonase activity in turkey and chicken blood and in turkey liver indicates that PON2, if expressed, does not hydrolyze paraoxon.
What are the official names of this protein?
Serum paraoxonase/arylesterase 2, PON 2, Aromatic esterase 2, A-esterase 2, Serum aryldialkylphosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the paraoxonase family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: ATG32_YEAS2
Sequence: MVLEYQQREGKGSSSKSMPPDSSSTTIHTCSEAQTGEDKGLLDPHLSVLELLSKTGHSPSPMGQNLVTSIDISGNHNVNDSISGSWQAIQPLDLGASFIPERCSSQTTNGSILSSSDTSEEEQELLQAPAADIINIIKQGQEGANVVSPSHPFKQLQKIISLPLPGKEKTPFNEQDDDGDEDEAFEEDSVTITKSLTSSTNSFVMPKLSLTQKNPVFRLLILGRTGSSFYQSIPKEYQSLFELPKYHDSATFPQYTGIVIIFQELREMVSLLNRIVQYSQGKPVIPICQPGQVIQVKNVLKSFLRNKLVKLLFPPVVVTNKRDLKKMFQRLQDLSLEYGEDVNEEDNDDEAIHTKSRSYCRNKKAENSKKKSPKSNKKPKRKKQKFFTSWFTWGISITIGISFGCCVTYFVTAAYEHQTVKSLSLRPSILASLLSLDSSSDTINTPATASPSSTEQFLWFDKGTLQINFHSDGFIMKSLTIIKETWGKMNTFVLHALSKPLKFLENLNKSSEFSIDESNRILALGYILL
What is the function of this protein?
Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria.  Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Recruits ATG11 to the surface of mitochondria.  Promotes also autophagy-dependent peroxisome degradation (By similarity).
What are the official names of this protein?
Autophagy-related protein 32, Extracellular mutant protein 37.
What is the protein family that this protein belongs to?
Belongs to the ATG32 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Vacuole membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass membrane protein. Note=Is recruited to the preautophagosomal structure during mitophagy and imported into the vacuole along with mitochondria during starvation.
Protein: RL31_ACAM1
Sequence: MAKPDIHPKWYPEAKVYCDGEVVMTVGSTQEELHVDVWSGNHPFFTGTQKIIDTEGRVERFMRKYGMSESQGAGGKGNAKKKDEK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: HEMF_CERS4
Sequence: MTNIALLQSLGLFDARVPRYTSYPAAPVFSGAVGADFQAQAIEALDPAVPISVYVHVPFCERLCWFCACRTQGTQTLAPVEAYVGTLLQELELVKQHLPAGVKAGRLHWGGGTPTILSPELIHKLAQAIKAVIPFAEDYEFSVEIDPMMVDEPKIRALSEEGMNRASIGIQDFTDIVQNAIGREQPFENTKACVETLRRYGVHSLNTDLVYGLPHQNRESLAATIDKVLSLRPDRVAIFGYAHVPWMAKRQKLIDETVLPPDIERHELANLAARLFTEGGFERIGIDHFALPDDSMAVAARSRKLRRNFQGYTDDTCPTLLGIGASSISKFEQGYLQNTAATAAYIKSIEEGRLPGYRGHRMTEEDYLHGRAIEMIMCDFFLDLPALRARFGEPAETMVPRIAEAAEKFTPFVTVDADGSMSIAKEGRALARMIARLFDAYETPEARYSQAS
What is the function of this protein?
Anaerobic transformation of coproporphyrinogen III into protoporphyrinogen IX.  Dedicated to bacteriochlorophyll biosynthesis.
What are the official names of this protein?
Coproporphyrinogen III oxidase, anaerobic 1, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_CARHZ
Sequence: MKLVFAGGGTGGHLYPALAIAQSWKESHPNDEILFVGTPRGIENTVVPKYGFPLYLLPVEGIPRKVSWETLKKLFLVPKSLINAFIFLKKEKPDIVVGTGGYASFPVVFAATVLKIPTVIHEQNAYPGIANKILAARVDAVCLTFGEAKKRMKAKNLYETGLPVRREFFTNAANRNELRKKMGVGKDELLLVAFGGSQGALTINKVVGYLLPEIMLRPNLRLVWATGPRNYENLKQKYKNLPERVQMVPYIDNMPEVLPAADLAITRAGAATLAEIAASKVPAVLIPYPYAAENHQEHNARAFVSHGAAVLLRDAECSEDRVKATILPLLDSPEKLVKMAENAGKVLRRDSLKEITGIMEALLKPKSNKKT
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HGD_CAUSK
Sequence: MDLQYQSGFANHFSTEAVPGALPVGQNSPQAPPYGLYAEQLSGTAFTAPRHENRRSWLYRLRPSAGHGPYAPYVQERLKSGPFGAAVPTPNRLRWDPLEIPEAPLDFVDGLVTLAGNGDVATQAGMAAHLYLANRSMIDRVFQNADGELLIVPQLGALRFVTELGVIDAAPGEVVVIPRGVRFRVELEGPVRGYVCENYGPMFRLPELGPIGSNGLANSRDFLTPVAAFEDVERPTEVIQKFQGGLWTGTWDHSPLDVVAWHGNLAPYKYDLARFNTMGTVSFDHPDPSIFTVLTAPSEIPGTANVDFVIFPPRWMVAEHTFRPPWFHRNVMSEFMGLVTGAYDAKAGGFSPGGASLHNMMSDHGPDVASHKAASEADLSPHKIEATMAFMFESRWVIRPTKYALETSELQADYDACWTGFPKAKLP
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: FBX39_MOUSE
Sequence: MDEDCEVTQLQEQSCWATLPDVCLRRVFWWLGDRDRSRAALVCRKWNQIMYSADLWRYRTITFSGRPSRVHASEFESALWYIKKFGRYLEHLEIKFLNPYNAVLTKKFQVTMRGLLSCLGKSNNRLRSLSIQHLELDRLVWRNSIRGSLIKSLSFFLKKMGKHLDHLSLKGARLTVEQGCHILNSLSYMQNENMASELNIEDFFSHHLAVYGSSQFNKAMATFRNLTFLTLNYNCISDELLETLSENNAGTLRTMNIKCHVHDPHGQVVWGMSWAKLARQASNLKVNFFFERVMKYERLARILLQEIPVRSISLRSCYFSDPDWSMRPTLTDLLPTFRNTLQKLTFEFNNNHESLDEQLHLLILACRKLFYFKIWAFLDVKFVERILKSQEEGQCSLHTLKVRIYTNRYETNEEDRTLREIYRKYRKLIDSELNYFVVAYPMM
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
F-box only protein 39.
Protein: AROA_LEUMM
Sequence: MIKLTKAEKNGLHGEITVPGDKSISHRALMFGAIAEGKTVIDNFLMSDDVMHTMGVFRALGVEIDHTESQATVIGKGLTNFKAPSAGLDMGNSGTSTRLLMGLLSKQPFDLNIFGDSSLSKRPLRRVADPLSMMNAQFELSNDEFLPAVIKANTELNGITYHMPVASAQVKSAILLAGIQAEGETTIIEDLPSRDHTERMLRQFGGQIKTDNGVITVKKQSKLSGQHVLVPSDISSAAFFMVAGLITPNSEITIKKVGVNPTRDGVIKLLERMGAEITQKPIASDGEPLADITVKAQTLHGIAITAEDIPGAVDELPILALAATQAVGDTIISGAEELRVKETDRISTVISELTKLGADIDEKPDGMVIHGGTLLHTSNGSTLLDSHGDHRIGMMNVIASLITEGDVVLTGEEAMSVSYPGFVEDVSSIKREWL
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_MALP2
Sequence: MKILVVNKKLHFNYEVLEKIEAGIELKGVEVKSIHLNNANISDSYVIFKRNEAYILNMNIAPYSHGNIYNVDPLRTRKLLLHKNEIIKYQMRIKKESLTMVPSKIYWRKNKLKVEIALAKGKKQFDKRQTIKDRDNSREARKHIRV
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.