PharMolix/UniProtQA huggingface dataset:
Protein: ATPH_ATRBE
Sequence: MNPLVFAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRMA_ECOLC
Sequence: MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: NRT1_YEAST
Sequence: MSFSSIVSKFLRYLEIPAKNRTAVNFLRNPDLQPIKSANQTWGFWSNLAYWGAVSFTAGTWMSGSAALSVGLSYPETIVSFLLGNVLTIIFTMANSYPGYDWKIGFTLAQRFVFGIYGSAFGIIIRILMSIVNYGSNAWLGGLSINMILDSWSHHYLHLPNTLSPSVAMTTKQLVGFIIFHVLTALCYFMKPYHMNYLLIWSCVATCFAMLGIVIYLTKNAHGVGELFTSTKSTVTGSKRAWAWVYMISYWFGSISPGSTNQSDYSRFGSSNLAIWTGSVCALLIPATLVPIFGVISASTCDKLYGKQFWMPMDIFDYWLTNNYSAGARAGAFFCGLCFTMSQMSSTISNCGFATGMDMAGLLPKYVDIKRGALFCACISWACLPWNFYNSSSTFLTVMSSFGVVMTPIIAVMICDNFLIRKRQYSITNAFILKGEYYFTKGVNWRAIVAWVCGMAPGLPGIAWEVNNNYFHDSGIVKFFYGDSFFSFLISFFVYWGLCVFFPFKITVRHDDKDYYGAFTDEEARKKGMIPYSEISEEEIRAYTLGECYTTGHEYKPESSDNESPELIKTSSENTNVFEIVHQKDDEKHSFSTTQQVV
What is the function of this protein?
High-affinity pH-dependent nicotinamide riboside transporter which also transports thiamine with low affinity.  Involved in 5-fluorocytosine sensitivity.
What are the official names of this protein?
Nicotinamide riboside transporter 1, Thiamine transport protein 71.
What is the protein family that this protein belongs to?
Belongs to the purine-cytosine permease (2.A.39) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMJ_HISS2
Sequence: MVNQKIQLICETESAVQFTALCQQKGLIHDPNSYLALVQTKVEGQVRLELRKLDEPKLGAVYVDFVTGTMAHRRKFGGGRAEAVAKAVGIKGNYLPTVIDATAGLGRDAFVLAALGCKVRLVERHPVVHLLLQDGLKRAYADAEIGTMMQANMQLLDIAHIQELNSSEEGADVVYLDPMYPHKQKSALVKKEMRIFQHLIGADLDADMLLEPALLLAQKRAVVKRPDYADFLAKKTPHFSHQTKNHRFDIYLKT
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_ACIAD
Sequence: MSNFLPAEEQLALIQRGTHEIISEEDLLKKLKENRPLRIKAGFDPTAPDLHLGHTVLINKLKAFQDLGHEVTFLIGDYTAMIGDPTGKSATRPPLTREQVEANAKTYQEQVFKILDPNKTKVRFNSEWFNQRTAADLIQLASQQTVSRMLERDDFTKRYNNHQPIAIHEFLYPLVQGYDSIALEADVELGGTDQTFNLLMGRTLQGRYGQESQVCITVPILEGLDGVNKMSKSLGNYIGVFDAPGAMYQKVLSMPDTLIERYFELLSFKSLDEIQGLLDEMANGRNPQDLKKILALELVERFHDADAAANAHKGAGNIITEGEIPEGTPEVTISRGEFGGEIFIASIVRLAGLTKNAAQAKDAVSRGAVKVDWQVVDANFSVKENKTYLIQAGKKAIAQVTFTD
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_PSEAB
Sequence: MSTVVEKSGEAKPGKVEVGVKLRGAEKVARIPVKIIPTEELPKKPDWIRVRIPVSPEVDRIKQLLRKHKLHSVCEEASCPNLGECFSGGTATFMIMGDICTRRCPFCDVGHGRPKPLDVDEPTNLAIAIADLRLKYVVITSVDRDDLRDGGAQHFADCLREIRKLSPGIQLETLVPDYRGRMDIALEITANEPPDVFNHNLETVPRLYRSSRPGSDFEWSLDLLQKFKQMVPHVPTKSGLMLGLGETDDEVIEVMQRMREHDIDMLTLGQYLQPSRNHLPVQRFVHPDTFAWFAEEGEKMGFKNVASGPLVRSSYHADQQAHGNKIG
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_ZYGRC
Sequence: MGIKGLNAIISEHVPSAVRKSDIKAFFGRKVAIDASMSLYQFLIAVRQQDGAQLSTESGETTSHLMGMFYRTLRMIDNGIKPCYVFDGKPPILKSFELKKRSDKRVDTEKKLEEAVDQAEKLKQERRLVKVSPEHNDEAKYLLKLMGIPYIVAPCEAEAQCAQLAKDGKVYAAASEDMDTLCYKTPYLLRHLTFSEAKKEPIHEIDTELVLQGLELTQEQFVDLGIMLGCDYCESIRGIGPVTALKLIKEHGSLEKIVEFIESGQANNKWKVPEDWPYNEARQLFLNPDVVNSQDINLKWNPPDEEKLIEFLCHEKKFNEERVKSGIKRLQKGLKSGVQVRLDGFFQKVPKTKEQLAAATAKAKAAKKTKGKTGKVSKR
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: TRPF_BORPD
Sequence: MRTRVKICGLTREADIASAVQAGADAIGFVFYPGSKRYVQPVLAARLRRTVPAFVDVVALFVNPAPADVQAVLDQVGPDLIQFHGDESAAECARYGTRFLRAFRTGAPGLDTPGNLAAACRAYDAAAGWLFDSYSAGYGGSGQAFDHALLAGVRADAAARPLILSGGLNAANVGTAIEACRPWAVDVSSGVETAPGEKSPDKIRALLDAVRQADDRLRGL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: ILVD_MOOTA
Sequence: MRSDAMKTGLARAPHRSLLKAMGLTETEIERPIIGVVNAHNELIPGHIHLNNLVEAVKAGVRLAGGTPLEFPTIGVCDGLAMNHVGMKYSLASRELIADMIEVMAMAHPFDALVFIPNCDKIVPGMLMAAARLNLPAIFISGGPMLAGRYQGRDVSLSTMFEAVGAVQAGKMTEQELAALEDCACPGCGSCAGMFTANTMNCMVEALGMGLPGNGTTPAVSGSRVRLAKEAGMQVMKLLQENIRPLDIMTATAFRNAVAVDMALGGSTNTCLHLPAIAHEAGVKLDLNTFNEINRRTPQICKLSPAGSQHIQDLDEAGGIPAVMNELYRHGLIDGSALTVTGRTVADNVSGRVVSRREVIRPVEDPYSREGGLAVLYGNLAPEGAVVKKGAVLPEMMRHEGPARVFNSEEEAFAAIMGKQIKPGDVVVIRYEGPRGGPGMQEMLSPTAALAGMGLDSSVALITDGRFSGASRGASIGHVSPEAAAGGLIALVEEGDIIAIDIEAGKLELKVPEEEIARRRQNWQAPPPKITGGYLGRYARMVTSGARGAVLE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: TRUA_ZYMMO
Sequence: MNRYRLTVEFDGRNFMGWQRQKHGATIQGSIEEAGASIAGQPTPVQAAGRTDAGVHGLAMTAHIDVARDFTPFRLMEALNARLKPRPIAILSCEQVDPEWHARFSCIGRRYLYRIINRRPPLTLEAGRAWHVIKPLDAETMDIAAKRLIGLHDFTTFRSVHCQSKSPVKTLDHLDVRRIGDQIEITAAARSFLHHQVRSMVGCLVLVGQGQWTADDMTTALEARNRAALGFNAPPDGLYFTQAIY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CYTA1_PIG
Sequence: MESDKMMPGGLTEARPATPEIQEIATTVKSQLEEKTNKTYEKFEAVEYKSQVVAGINYYIKVHVGGNSYVHIKVFKSLPYQNKPLELSGYQVDKTKDDELTGF
What is the function of this protein?
This is an intracellular thiol proteinase inhibitor.
What are the official names of this protein?
Cystatin-A1, Stefin-A1.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y7744_DICDI
Sequence: MEISDILFDDLVVGEINDDFICVICSHLQVDIYQCVEGHFACKNCFLKMIELKKQCMTCRCEIKSIESLSKNRYLEKEVRKLNIYCPNSFSDLKNSIKDENACKDIITIEGLETHLKNCKFTLKECPNNKNCNDDNKNKECLKIRQGEFDHHLKECPNSLIKCEHCSIEITRSKQTDHIENHCLKVLKQCEFCFKLIERGEFNNHQDTICLSKLIKCPFNEGGCVDLVKRSDIKEHLSVLAGEHLLYSITMINSLSLKLEKSNSELQESISYSRLLKKDFKELKKSKSYSGRWVIEKWSEKLKQYGKGQSIQFQKFNTSTSPSSAFSYFTLRLFPNGQYNGETISIHLVKLFRNKSRISFSFEIENHINPSSNEEIDSRFLFGNLNDYYSTIFYKEYNKENGFISEDDTLVIHFNVEILKYYDDTFITK
What is the function of this protein?
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
What are the official names of this protein?
TNF receptor-associated factor family protein DDB_G0267744.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FITM2_BOVIN
Sequence: MEHLERCAWVLRGTLVRSAVRKYLPWALAASMLAGSLLKELSPLPESYLSNKRNVLNVYFVKVAWAWTFCLLLPFIALTNYHLTGKAGLVLRRLSTLLVGTAIWYVCTAIFSNIEHYTGSCYQSPALEGERKEHQSKQQCHGEGGFWHGFDISGHSFLLTFCALMIVEEMAVLHEVKTDRNHCLHAAITTLVVALGFLTFIWVWMFLCTAVYFHNLSQKVFGTLFGLLGWYGTYGCWYLKSFSPGLPPQSSSLNLKQDTYKK
What is the function of this protein?
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity).  Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates such as oleoyl-CoA/(9Z)-octadecenoyl-CoA and arachidonoyl-CoA/(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA in the endoplasmic reticulum (ER) lumen (By similarity).  This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis (By similarity).  Directly binds to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis (By similarity).  May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation (By similarity).  Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity).
What are the official names of this protein?
Acyl-coenzyme A diphosphatase FITM2, Fat storage-inducing transmembrane protein 2, Fat-inducing protein 2.
What is the protein family that this protein belongs to?
Belongs to the FIT family. FIT2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y148_PYRAR
Sequence: MAIAESFRLEDGFSVYAGVRATRDAVVEDAAFAVAKLGGADGTDAAEKIVAALIRPDVSIIMLDGCIVSFYNWIDGEALYAKFQKPVACYVFEEPEGRVEEAVRKLFPDWPDRLRAIEKLGSPTPYYTKAGYKIYVRSWGIDPIYAGKAAELAMKLGKMPEPLRVARIMAAGARALLNTLGLRLVNGH
What are the official names of this protein?
UPF0215 protein Pars_0148.
What is the protein family that this protein belongs to?
Belongs to the UPF0215 family.
Protein: NUDK_CITK8
Sequence: MSQKITLIKDKVLSDNYFILRNITYDLTRKNGDVIRHKREVYDRGNGATILLYNREKQTVVLIRQFRVATWVNGNESGQLIETCAGLLDNDEPEACIRKEAIEETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDSQRANAGGGVEDEDIEVLELPLTQALAMIKTGEIRDGKTVLLLNYLHSSSLIY
What is the function of this protein?
Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.
What are the official names of this protein?
GDP-mannose pyrophosphatase, GDP-mannose hydrolase, GDPMK.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudK subfamily.
Protein: MCFZ_DICDI
Sequence: MTGKEENKQQQHVNFPWKRLVAGAVAGTADVWACHPLDRIKTQLQNNPGKSIVGTFGDIVSKGKGFTGGVNALYEGILPMTAEAIFKVGIRYFAFSWFTEQYKTTVYKGETLNKKQQFGANLLGGAFAGTIESFVVVIPCELLKVRHMTQEHNKSFGTVFRDVLREEGFQGLYKGGSATLLRQITNHMIRFPTFYAISDYLKGGDHSVHLPVWQNLSAGAIAGTASTLFNNPLDTIKTRMQKQGQNQTTMQVVRGIYQETGVKGYWAGVIPRILRVAPGQAITWAVVELVMGILEPSSKKH
What is the function of this protein?
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial substrate carrier family protein Z.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RK14_EUGGR
Sequence: MIKPQTYLKIADNTGAQKIMCIRILGPNCQYANIGDIIIAVVKEAIPNMVVKKSDIVKAVIVRTVKGVRRESGMAIRFDENAAVIINNDRSPKGTRIFGPIARELREKEFVKIMSLAPEVV
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FLAB1_NATMM
Sequence: MFEQNDDRDRGQVGIGTLIVFIAMVLVAAIAAGVLINTAGMLQTQAEATGEESTDQVSDRLDIVSVSGDVDDPDDPTQINNISMVTATAPGSDPVDLNQTTAQFIGEGGEEMFNLSHEGVFINSIQGVSDEPDNNVLTESSDRAEVVFELDGAPGSYDIGYEALDESERLTVILTTDAGASTEQEIRVPSTFIEDEESVRL
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
What are the official names of this protein?
Flagellin B1.
What is the protein family that this protein belongs to?
Belongs to the archaeal flagellin family.
What are the subcellular locations of this protein?
Archaeal flagellum.
Protein: END4_BACCQ
Sequence: MLKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMEQNGIEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVLTPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVTYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLMHVPKILETPYVGEDKKDKKPPYKLEIEMLKNGTFDEGLLEKIKAQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: QNR71_COTJA
Sequence: MSQAHRHLALLLPAEAVLCAAAMRFQDVLSNGRTAPVTNHKKIQGWSSDQNKWNEKLYPFWEDNDPRWKDCWKGGKVTTKLVTDSPALVGSNVTFVVTLQFPKCQKEDDDGNIIYQRNCTPDSPAAQDQYVYNWTEWIDNCGWENCTSNHSHNVFPDGKPFPHYPGWRRRNFVYLFHTVGQYYQTIGRSSANFSVNTANITLGKHIMAVSIYRRGHSTYVPIARASTTYVVTDKIPILVSMSQKHDRNISDSIFIKDSPITFDVKIHDPSYYLNDSAISYKWNFGDGSGLFVESGATTSHTFSLQGNFTLNLTVQAIIPVPCKPVTPTPSLPTPAVTTDASSNSDPSAPNEMAEDNPDGGCHIYRYGYYTAGITIVEGILEVNIIQMTSIQMTESQAENPLVDFVVTCQGSFPTDVCTAVSDPTCQVSQGMVCDPVVVTDECVLTIRRAFDEPGTYCINITLGDDTSQALASALISVNGGSSSGTTKGVFIFLGLLAVFGAIGAFVLYKRYKQYKPIERSAGQAENQEGLSAYVSNFKAFFFPKSTERNPLLKSKPGIV
What is the function of this protein?
Could be involved in melanogenesis.
What are the official names of this protein?
Protein QNR-71.
What is the protein family that this protein belongs to?
Belongs to the PMEL/NMB family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS20_CLOK1
Sequence: MANIKSAKKRIKVIKTKTLRNKIIKSSLKTTIKKFLAAVESGNVEEAKVSFTATVKALDMAASKGVIHKNKASRNKSKLALKLNKLTA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: LRGB_BACCQ
Sequence: MASTMTPYFGIVVSLIAYGIGTLLFKHSKGFFLFTPLFVAMVLGIVFLKVGNFTFEEYNTGGKMISFFLEPATIAFAIPLYKQVDKLKKYWWQILSAIVVGSICSVIVVFIVAKAIGLDTAVMNSMLPQAATTAIALPISESIGGIPAITSFAVIFNAVIVYALGALFLKTFRVKHPIAKGLALGTAGHALGVAVGIEMGEVEAAMASIAVTVVGVVTVVVIPMFMPFIG
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLPK_SHESH
Sequence: MAKKYVVALDQGTTSSRAIIFDHDANIVSVSQREFPQIYPQAGWVEHDPMEIWASQSSTLIELLARSGIHGSEVAAIGITNQRETTVIWDKLTGKPVYNAIVWQCRRSSHICDELKAQGLEDYVRETTGLLLDPYFSGTKIKWILDNVAGVRERAEKGELLFGTIDTWLVWKLTEGKVHVTDPTNASRTLLFNIHTQQWDSKLLEALNIPESLLPEVKPSCAVYGKTRIAGEGGEISIAGIAGDQQSALFGQLCIDEGMAKNTYGTGCFLLMNTGKQAVKSTHGLLTTVAIGADCEVNYALEGAVFMGGATIQWLRDELGLIRDAQDTEYFASKVEDTNGVYLVPAFVGLGAPYWDPNARGALVGLTRGSNRNHIIRAALEAIAYQSRDLLDAMAKDSGVMLKQLKVDGGAVSNDFLMQFQADITNVEVQRPAITETTAMGAAFLAGLAVGFWSSTSELKHKADIERTFIPSISAEKCDELYCGWNRAVTQTIKS
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RL332_STRR6
Sequence: MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYTTHRETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: EFG2_TREDE
Sequence: MGNDISKMRNIGISAHIDSGKTTLSERILFYCDRIHALHEVRGKDGVGATMDNMELEKERGITIQSASTQVKWKDYTVNVIDTPGHVDFTIEVERSLRVLDGAILVLCSVGGVQSQSITVDRQLKRYHVPRIAFVNKCDRTGANPFKVRMQLREKLGLNAYMMQIPIGLEDKLEGVVDLVTMKAMYFEGENGTQIRMAEIPQHLLADAQKYREEMIDAATMFSDELAEAFLEGAETEEMIRAAVRKGTLAEQFVPVFLGSAYKNKGIQPLLDAVGYYLPDPTEIENTALDLDENEKPVVLGTDENAPVVALGFKLEDGKYGQLTYVRVYQGTLKKGEELFNTRAKKKFKVGRLVRMNSATMEDINEGGPGDIVALFGIDCASGDTFCGENLNYAMSSMYVPDPVISLSLTPKDKQAADQMSKALNRFTKEDPTFRSYVDKESNQTIIQGMGELHLEVYIERMKREYKCDVETGMPQVAYREAITQRADFNYTHKKQTGGSGQFGRVAGFIEPCTEQDYEFDNQIKGGAIPSEFIPSCDKGFKEAIKRGTLIGFPIVGTKVTINDGQSHPVDSSDMAFQAAAIGAFREAYKAAKPAILEPIMKVSIEGPQEFQGNIFGLINQRRGIIISSTEDDNFTRVDAEVPLSEMFGFSTILRSSTQGKAEYSMEFAKYGKAPASISEELIKEYEAKRLAEKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NVFJ_ASPN1
Sequence: MTVETITPQTPVSLPKTAVICNDFKLDRVNEPARSILEKYSKIPSREILEHVRKIRDEAFAEFPYPCIGRFSFLDLSISQSPKYPEILHRVVNGEKFLDLGCAFGQELRQLVYDGAPSDNLYGSDLHNGLMHLGYDLFRDVSTLKSRFIATNILEGNSDLISQLSGQMNIIYSSLFFHLFDWDQSLVIAKHVLRLLSLQPGSMITGRFVAYRDWNFAKEKLGSTLRFYFDLSSWTQLWKQVEVDTGSKLNIEHWEQSDNMLTDNGIGGYMLCFAITRQ
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety (PubMed:29968715).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase nvfA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (PubMed:29968715).  DMOA is then converted to farnesyl-DMOA by the farnesyltransferase nvfB (PubMed:29968715).  Epoxydation by FAD-dependent monooxygenase nvfK, followed by a protonation-initiated cyclization catalyzed by the terpene cyclase nvfL leads to the production of asnavolin H (PubMed:29968715).  The short chain dehydrogenase nvfC then as a 3-OH dehydrogenase of asnovolin H to yield chemesin D (PubMed:29968715).  There are two branches to synthesize asnovolin A from chemesin D (PubMed:29968715).  In one branch, chemesin D undergoes Baeyer-Villiger oxidation by nvfH, methylation by nvfJ, and enoyl reduction by the nvfM D enoylreductase that reduces the double bond between C-5'and C-6', to form respectively asnovolin I, asnovolin K, and asnovolin A (PubMed:29968715).  In the other branch, the methylation precedes the Baeyer-Villiger oxidation and the enoyl reduction to yield asnovolin A via the asnovolin J intermediate (PubMed:29968715).  Asnovolin A is further converted to fumigatonoid A by the Fe(II)/2-oxoglutarate-dependent dioxygenase nvfI that catalyzes an endoperoxidation reaction (PubMed:29968715).  The alpha/beta hydrolase nvfD then acts as an epimerase that converts fumigatonoid A to its C-5' epimer, which then undergoes spontaneous or nvfD-catalyzed lactonization (PubMed:29968715).  The following step utilizes the ketoreductase nvfG to produce fumigatonoid B (PubMed:29968715).  The dioxygenase nvfE further converts fumigatonoid B into fumigatonoid C (PubMed:29968715).  Finally the Fe(II)/2-oxoglutarate-dependent dioxygenase nvfF catalyzes two rounds of oxidation to transform fumigatonoid C into the end product, novofumigatonin A (PubMed:29968715).
What are the official names of this protein?
Asnovolin E/Chermesin D methyltransferase nvfJ, Novofumigatonin biosynthesis cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily.