PharMolix/UniProtQA huggingface dataset:
Protein: MTND_SODGM
Sequence: MRALTIYSDTDATAPRWQSHEGDAIQRELNAIGVRFERWQTDRELGANPDADTVIAAYQDAIDRLVAEKGYQSWDVISMRPDNPQRETLRTKFLAEHTHGEDEVRFLVEGAGLFCLHVQGKIYQILCEKNDLISVPAGTAHWFDMGEAPSFTAIRVFDNPEGWIARFTGDAIADEYPRLVR
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: ATL72_ARATH
Sequence: MGRLLLEPQANAPANANPKPKGGINDTYFDTNMVIILAALLCALICALSLNSALRCVLRITRRFTSDDQVSNASNANANLGRLAAATGLKKQALKQIPVGLYGSGIIDMKATECLICLGDFEDGEKVRVLPKCNHGFHVRCIDTWLLSRSSCPTCRQSLLLEQPSPMAVSRRDEDMVVSIV
What are the official names of this protein?
RING-H2 finger protein ATL72, RING-type E3 ubiquitin transferase ATL72.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACP4_CUPLA
Sequence: MASAAAGASICIKSASCSPLAPGRISSLRSVSLPVSRKSFPSLRSSKGSFARVSCQAKPETVAKVCRIVKKQLALPDDSEVNGLSKFSALGADSLDTVEIVMGLEEEFGISVEEESAQSIQTVQDAADLIEKLMEKKGH
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein 4, chloroplastic, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AP4E_DICDI
Sequence: MNSSALNLIQFLESSKIQVPGGLKSVKGILDFDFYDLVKNIGESTSREEEVHIIQNEIIKLKSCFSKEQSKDKKRECLIRMIYCHMLGYDVPFGHIQALNMTQDSEILNKRTGYLTLSLCLPERHELLIMAVNSILKGLNSSNYLEVCSALTAMCKLIDNDTIPAFLQKVLQLLNHQKPIVRKKSVTVLHRFYRLVGDSFLDDDQIIDKLRQSLCDRDPSVMSASICIFLDISEKHSTLKDNNNQINNNNNNNNSNQIKKKNNEEINRSKNLISMLKELVPSFVGILKQVAEGRLPNSYIYHGIHHPWLQINLLKLLSNLGYQDKDSSNHMYTVLLFTMQQSQKFKNNVGFAILYETIKTLTLIHPNLQLIEQCSKNIAIFLKGKHHNLRYFGIKALASIVKVSPKLVLPYQVEVIESLESPDETLKRKSFDLLYKMTNQTNVVPVCSKLIEQLVLSKDQNFKSELISQITNIAEKYSPNDIWYIDTISTVLSILPNENNKDNNNNNNNNNNNNNNYQFAYNLIRLVSEEDDIKVKQHISEIYLNNIMISNEQQQQQQQENQNNLQQFSDIYIKIMSWVISEYSNLIVSNNGVIESDIISYLCDLLEKDYQGETKSWIIIGIGKLVAQLGKSLPMLELMTKKFKSSKSLICQQRSSELNEILKNPKSMSLILPLDAYCEDIDFNKIFNKFNDYSNKVGGKQYIPYEKRKNTPLVDISDGSSSHSNEKGLNFQYPPPPDPFNPHHNQQQLYPVHQHQPPSNHQQQQQQQQQQQQQQLQLFPQQPQQPQQLLLLGEDDTINLNNNSLVPVNNDQQLQPHQHQQQQQNQQQQQQNQQQQQQQNPQYPNNQLVTVPDQNAPKPIGLPKPSKVLWTKKGFVGNKQTPPQNATPQQQQQQQQQQTQNTLSQQQIQKHQQTHNNIDPEKEKLAKQLFGGFSENNNRNENSNNTDNNQNNVGITSKLQNKKSNNENNINNNKKESYLEELIDLSPNLISNINITNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNLLLVDVEGDEQKEVKNSSCSSGNSELINLNLDENTTKNINGNLLGDDLEELNKN
What is the function of this protein?
Probable component of an adaptor protein complex.  Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection.  They control the vesicular transport of proteins in different trafficking pathways.
What are the official names of this protein?
AP-4 complex subunit epsilon, AP-4 adaptor complex subunit epsilon, Adaptor-related protein complex 4 subunit epsilon, Epsilon subunit of AP-4, Epsilon-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
Protein: VM1BI_BOTMO
Sequence: EQQKFSPRYIELVVVADHGMFKKYNSNLNTIRKWVHEMVNSMNGFYRSVDVTASLANLEVWSKKDLINVQKDSRETLKSFGEWRERDLLPRISHDNAQLLTAIVFDGHTIGRAYTGGMCDPRHSVGVVMDHSPKNLQVAVTMAHELGHNLGMHHDGNQCHCDAASCIMADSLSVVLSYEFSDCSQNQYQTYLTKHNPQCILNEPL
What is the function of this protein?
Snake venom zinc metalloproteinase that cleaves the alpha chain of fibrinogen (FGA) first followed by the beta chain (FGB) and shows no effect on the gamma chain.  Cleaves only the beta chain of fibrin, leaving the gamma-dimer untouched.  Shows proteolytic activity towards azocasein.  Causes defibrinogenation when intraperitoneally administered on mice.
What are the official names of this protein?
Snake venom metalloproteinase BmooMPalpha-I, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU1_PHOPR
Sequence: MKDQVIIFDTTLRDGEQALSASLTVKEKLQIAYALERLGVDVIEAGFPISSPGDFESVQTIAKHIKNSRVCALSRAVAKDIDVAAESLKVAEAFRIHTFISTSTIHVQDKLRRSYDDVIEMAIAAVKRARNYTDDVEFSCEDAGRTPIDNLCRMVEAAINAGARTINIPDTVGYTLPSEFGGIVAQLFNRVPNIDKAIISVHCHDDLGMSVANSMAAVQAGARQVEGTINGLGERAGNCSLEEIAMIIKTRSDFLGVETNIKHEEIHRTSKMVSQLCNMPIQANKAIVGANAFNHSSGIHQDGMIKNKNTYEIMTPESIGLKSQALNLTSRSGRAAVKNHMDTLGYIDGDYNLDTLYADFLKLADRKGQVFDYDLEALMYFANLRDEDDFFKLNYLSVQSGSIMATTSIKLQCGDEEKCEAAVGNGPVDALYQCIYRLTGYEIALDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTGLATDIVEASGQALLHVINSIYRADQIAEIKERIATV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: UDG_STRPQ
Sequence: MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKSKQLSLQATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIVSCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAESRKLNSHMVIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIINVLEEQESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFGRD
What is the function of this protein?
Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis.
What are the official names of this protein?
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: MURC_STRTD
Sequence: MSKTYHFIGIKGSGMSALALMLHQMGYKVQGSDVEKYYFTQRGLEQAGIPILPFDEKNITEDVELIAGNAFREDNNVEIAYAIKNGYKFKRYHEFLGHFMNQFTSFGVAGAHGKTSTTGLLSHSMKNITDTSYLIGDGTGRGSANAQYFVFEADEYERHFMPYHPAYSIITNIDFDHPDYFTSIDDVFSAFDDYAKQVQKGLFVYGEDSNLRKITSNAPIYYYGFEENDDFMATDIIRTTTGSNFKVKHDGQIIGEFHVPAYGRHNILNATAVIANLYVAGFDMALVAEHLKTFSGVKRRFTEKIISDTVIIDDFAHHPTEIIATLDAARQKYPSKEIVAIFQPHTFTRTIALLDDFAEALNEADAVYLAQIYGSAREVDHGDVKVEDLAAKINKPAKVVTVENVSPLLDHDNAIYVFMGAGDIQLYERSFEELLASLQTHM
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_STRE4
Sequence: MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAETGKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKILADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGLIKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLMERPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATAELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTNLERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAAA_BACSU
Sequence: MKVLVNGRLIGRSEASIDLEDRGYQFGDGIYEVIRVYKGVLFGLREHAERFFRSAAEIGISLPFSIEDLEWDLQKLVQENAVSEGAVYIQTTRGVAPRKHQYEAGLEPQTTAYTFTVKKPEQEQAYGVAAITDEDLRWLRCDIKSLNLLYNVMTKQRAYEAGAFEAILLRDGVVTEGTSSNVYAVINGTVRTHPANRLILNGITRMNILGLIEKNGIKLDETPVSEEELKQAEEIFISSTTAEIIPVVTLDGQSIGSGKPGPVTKQLQAAFQESIQQAASIS
What is the function of this protein?
Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine.  The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.  The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism.  This is an important process in the formation of D-alanine and D-glutamate, which are essential bacterial cell wall components (By similarity).
What are the official names of this protein?
D-alanine aminotransferase, D-amino acid aminotransferase, D-amino acid transaminase, DAAT, D-aspartate aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: MYPC3_HUMAN
Sequence: MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ
What is the function of this protein?
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands.  In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase.  It may modulate muscle contraction or may play a more structural role.
What are the official names of this protein?
Myosin-binding protein C, cardiac-type, Cardiac MyBP-C, C-protein, cardiac muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. MyBP family.
Protein: RIMO_ZYMMO
Sequence: MIKKLPTSPKIGMVSLGCPKALVDSERILTKLRSEGYNLSSQYDEADVVLVNTCGFIDSAKEESLDAIGEAMAENGRVIVTGCLGNEANRIRERFPDILAITGAQQYEEVVSAVHDAAPIEASPYVDLVPEQGLKLTPRHYSYLKISEGCNHRCSFCIIPSLRGDLVSRRADAILREAEKLVAAGTKELLVIGQDSSAYGVDLRHQEYRWKDRMVKADLTDLARGLGELGAWVRLHYVYPYPHVDNLIPLMAEGLILPYLDIPFQHASPSVLKRMKRPANEVKILDRLTKWREIVPDIALRSSFVVGFPGETEQDFQYLLDWLDEAQLDRVGAFRFEAVEGAAANAFDGAVPEEVKNERYQRLMEKAAQISEAKLQAKIGRDIATIIDRTDGEGGASGRSYADAPEIDGEVHLRDADNLKIGDIVTVRVEDADEHDLFGVALS
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_BUCBP
Sequence: MLNPIVRKFQYGQHIVTLETGIMARQATAAVLTSMDDTTVFVTVVGQKKLQTEQKFFPMTVNYQERTYAAGRIPGGFFRREGRPSENEILIARLIDRPIRPLFPKRFFNEVQIIATVVSLNPQVNPDIVAIIGASAALSISGMPFLGPIGAARIGYINNQYILNPNVNEIKSSSLDLIISGTEESVLMVEAEANMLTEEQIINAINYGHEQQKIVIKNIEHFAKKVKIPVWEQCLYPVNDDLEKRIIEISEQEIVKAYNIFDKVIRLDVLDKIKSKAIEIIISEYSGIDEFEITSIISNIERKIVRNRVLKNRIRIDGRNKDEIRTLDVRTGVLPRVHGSALFTRGETQSLVSVTLGTSRDAQNLDELLGDKTDNFLFHYNFPPYAVGEIGMVGSPKRREIGHGKLAKRSILAVMPKLDLFPYTIRIVSEITESNGSSSMASVCGASLALMDAGVPISNAIAGIAMGLIKEGDDFVVLTDILGDEDHLGDMDFKISGSKKGITALQMDIKVKGITNEIMKLALYQAKNARIHILNIMKKSLNVPRKDISIFAPRIHTIKINPEKIKDVIGKGGSVIRMLTEETGTTIEIEDDGTVKISAVMQEKAKCAIQRIKEITAEVEVGSVYTGKVTRIVDFGAFVSIGIGKEGLVHISQIAHKRVDKVSDHLRLHQEIFVKVLEVDRQGRLRLSIKGAK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_BACC0
Sequence: MKVRPSVKPICEKCKVIRRRGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: HIS8_CLOB1
Sequence: MSKYWSNITKDIEPYVCGEQPKNKKIIKLNTNENPYPPSPKVLQAIENAAKDDLRLYPDPNCDTLRKTIANYYNLSKEEVFIGNGSDEVLSLSFLTFFNPEETVVFSDISYSFYPVYANLYKLDYELAKLREDFSIDIEDFKNTKGGAIITNPNAPTGLYLSLDSIKQILEDNINKVVMVDEAYIDFGGESSVSLIKDYPNLLVIQTLSKSRSLAGMRIGFALGKKELIEGLNRIKNSFNSYTIDRISSLAAIEAIKDEEYFKECTLKVIKTRNWTINELGKIGFKIIPSKANFIFITHDTYQAEDILIKLRDENVLVRYFNKDRISNYLRVSIGSKEEMEIFMDKIKKIINKL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RAB15_BOVIN
Sequence: MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQKRQVGREQGQQLAREYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELEGLRTRANHELALAELEEDEGKPEGPANSSKTCWC
What is the function of this protein?
May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal.  EHBP1L1.
What are the official names of this protein?
Ras-related protein Rab-15.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: PYRD_TRIV2
Sequence: MDIYKFAVRPLLFDLVKADPEWLHQQTMRSLSWLSHTSDRTSTKWVQNILQKSLCIEDSRLEQNLFGLRFPNPVGLAAGFDKDGVAARIWSSLGFGFAELGTVTFVAQPGNPPPRLFRLPLDQAALNRMGFNNHGAAVMATRLADEKGLFSIPIGINLGKSKVTPLEAAAEDYLNSFRLLKELGDYFVVNVSSPNTPGLRSLQDASMLSSILDVLQKENQSHKPIFVKIAPDLEWEAIADIIGLAKTYQLAGIIATNTTIRRDGLKTQVIEQTGKAPQEEAGGISGAPVRDRSTEIIRFIWQQTQGEIPIIGVGGIFTPEDAWAKITAGASLIQVYTGWIYQGPMMVSQILTGLLAKLEEHELNSISEAIGLEFKS
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LPLA_YERPB
Sequence: MSSLRLLISDSYDPWFNLAVEECIFRQMSPDQRVLFLWRNADTVVIGRAQNPWKECNTRRMEQDGVKLARRSSGGGAVFHDLGNTCFTFMAGKPGYDKTISTQIILNALASLGIQATASGRNDLVVINGEDERKVSGSAYKETKDRGFHHGTLLLNADLSRLADYLNPDPKKLQAKGITSVRSRVTNLVELLPGIDHEKIRTAIEQAFFAYYDEQVSAEVISPQSLPNLPGFTEQFAKQSSWEWNFGQAPAFSHVVDTRFTWGGIELHFDVLHGAIDRCQIFTDSLNPTPLEALAQRLQGAAYRPDAIDKICQHWIDDFPELQTELQQACHWLVEVLR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_FRATN
Sequence: MNVLEISAQTLRNNIRIIKEYVGSAKICFPVKANAYGHGLELIVEHSHDLVDFFAVANVLEAFRVLDVVEKPVMIFGVIEYNYIDRILSKNIRVSIQDYNDIEKLEKFAKYYNKKPFVHVNLNTGMNRMGVDYNDACRTIQRAYESDWLILEGVYSHLACADNRDHPTNIKQKNRFDSIVEFTKGLSQDIICHLSNSYGFLGQKGICYDMVRPGILSYGFLPEFYVDRVIREIKPIARLLSKVVKIITLQEGEGVGYSLIYRGFEGEQLAVIPIGYGDGFPRELGDRGFVNINDVMYPMAGRMSMDGLTVSLGINEYDVKVSDTVELISAIPRNRNSAFSIAKQTNTIEYDIMSTLNDRIIRKII
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: RS18_BACLD
Sequence: MAGGRRGGRAKRRKVCYFTSNGITHIDYKDVDLLRKFISERGKILPRRVTGTSAKYQRKLTVAIKRARQMALLPYVAGE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: LPLT_ECO81
Sequence: MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLADWHILVALVACALAYGGAVVANIYIPKLAAARPGQSWNLISMTRSFLNACTSLWRNGETRFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVLGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWIWQRRH
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y643_STAAW
Sequence: MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD
What are the official names of this protein?
UPF0178 protein MW0643.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: COPT1_RAT
Sequence: MRMNHMEMHHMGMNHTDDNITMPPHQHPTTSASHSHEMMMPMTFYFGFKNVDLLFSSLVINTPGEMAGAFVAVFLLAMFYEGLKIAREGLLRKSQVSIRYNSMPVPGPNGTILMETHKTVGQQMLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKAVVVDITEHCH
What is the function of this protein?
Mobilizes copper(1+) out of the endosomal compartment, making copper(1+) available for export out of the cells.
What are the official names of this protein?
High affinity copper uptake protein 1, Copper transporter 1, rCTR1, Liver regeneration-related protein LRRGT00200, Solute carrier family 31 member 1.
What is the protein family that this protein belongs to?
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to the apical membrane in intestinal epithelial cells.
Protein: Y1758_AQUAE
Sequence: MKISEVLEFKVEGEEERLDKFLARAYPDFSRSYIKKLVKEGLVYVNGEEVRKPSRKLREGERVILHVPEPEPLDVKPENIPINIIYEDEDIAVVEKPCGLVVHPSPGYTSGTLVNALLYHIKDLSSIGGVERPGIVHRLDKETAGVMVIAKNNTAHRNLVRQFQERKTEKFYKVLVKGLVKKDYGAIDTPIARHPVDRKRFWVRKEGKEALTEYWVLKRYEKYEITLLKVKIHTGRTHQIRVHFASIGHPVLGDRTYGFKSSSVPKELLSLMGECNMLIAYHLGFYHPTKGEWMVFEIEEPETFKSVYSWLEEHSP
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase aq_1758, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: ACEK_ESCF3
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKSRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFYPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIIRHLTEMLGTDNLAESHLQVANELFYRNKAAWLVGKLNTPFGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPTLMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPSRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYRPQV
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_I47A0
Sequence: MDPNTVSSFQDILMRMSKMQLGSSSEDLNGVITLFESLKLYRDSLGEAVVRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.