PharMolix/UniProtQA huggingface dataset:
Protein: RT08_YEAST
Sequence: MSLVKLANTCAHLQNCSKVRVALTSIPYTKLQLQFAYNLYQQGFLSSLQKGSTMGPDKDFVEVTPDNISTRRLWVGLKYRDNKPVLSSCKLISKPNSRIHLPMEDMKKLCSGVTIRNIKPLQPGELILVRAHNNIMDINEAISKKLDGEVLCRVK
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
37S ribosomal protein S8, mitochondrial, Mitochondrial small ribosomal subunit protein uS8m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: CYB_PERIO
Sequence: MTIMRKTHPLMKMVNHAFIDLPAPSNISGWWNFGSLLGLCLIIQILTGLFLSMHYTPDTLTAFSSVAHICRDVNHGWLIRYMHANGASLFFICLYLHIGRGIYYGSYMYKETWNIGIVLLFLVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLNRFFAFHFILPFIIAAMAMVHLLFLHETGSNNPLGIPSDSDKIPFHPYYSYKDLLGGAALLAFFFTIVLFFPDALGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLXHTSNQRSLTFRPISQTMFWILVSDLFILTWIGGQPVEPPFIIIGQIASILYFSIILILFPIAGMIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1892_STAA3
Sequence: MSFVTENPWLMVLTIFIINICYVTFLTMRTILTLKGYRYIAASVSFLEVLVYIVGLGLVMSNLDHIQNIIAYAFGFSIGIIVGMKIEEKLALGYTVVNVTSAEYELDLPNELRNLGYGVTHYAAFGRDGSRMVMQILTPRKYERKLMDTIKNLDPKAFIIAYEPRNIHGGFWTKGIRRRKLKDYEPEELESVVEHEIQSK
What are the official names of this protein?
UPF0316 protein SAUSA300_1892.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IMA5_XENLA
Sequence: MPTTNEADERMRKFKNKGKDTAELRRRRVEVSVELRKAKKDEQILKRRNVCLPEELILSPEKNAMQSVQVPPLSLEEIVQGMNSGDPENELRCTQAARKMLSRERNPPLNDIIEAGLIPKLVEFLSRHDNSTLQFEAAWALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPLYRDALINCNVIPPLLALVNPQTPLGYLRNITWMLSNLCRNKNPYPPMSAVLQILPVLTQLMHHDDKDILSDTCWAMSYLTDGSNDRIDVVVKTGIVDRLIQLMYSPELSIVTPSLRTVGNIVTGTDKQTQAAIDAGVLSVLPQLLRHQKPSIQKEAAWAISNIAAGPAPQIQQMITCGLLSPLVDLLNKGDFKAQKEAVWAVTNYTSGGTVEQVVQLVQCGVLEPLLNLLTIKDSKTILVILDAISNIFLAAEKLGEQEKLCLLVEELGGLEKIEALQTHDNHMVYHAALALIEKYFSGEEADDIALEPEMGKDAYTFQVPNMQKESFNF
What is the function of this protein?
Essential for selective protein import into nucleus.  Promotes signal-dependent binding of karyophilic proteins to the nuclear envelope.
What are the official names of this protein?
Importin subunit alpha-5, Karyopherin subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y144_LACLA
Sequence: MTHTHDHEHDHNHEPDYITLVDENGNESLFQILITIDGQEEFGKNYVVLQPTEFEEDEQGLIDVLAYSFTENADGTEGDLQPIPEDAEDEWDMIEEVFNSFMDEQED
What are the official names of this protein?
UPF0473 protein LL0144.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: RS8_THETH
Sequence: MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: FB267_ARATH
Sequence: MYTPNDSMREEISLKVFVNHDWSKLCPDILRSILESLSSTDFHRAKTVCSDWYSNWKTCVKPLCPWRIMYVKDSLMLFKPGEDKIYKGTNVGLSNDSYYMASSGNWLLMVDSHLGFYIFNLLTSKRIDLPSMESSIRGGKVRFEQNHEHGFNWGHFVEPSRKVTVSKITITRESRAVLWIDERTGDFVVAWIFNYRYLFSYKKGDDSWWNWNNHWNMESLNLSFLDLAYRNSKLYIYITKSHIKVVDFSGNDPIEVIDKNPYWEHPFRYLTKKGEYINKRRIAIQKSGDVLIILSVLAQRSKEKVLFYIFKMNLASKIWERVESIGDDEMLIFGHGVTIRAPVQDVGDGIKSGSICFVSDVWPPYYSPAATNWGVFDLATSIIKWSKKDSFNNRYVQTYLFFPGFA
What are the official names of this protein?
Putative F-box protein At5g38270.
Protein: CK024_HUMAN
Sequence: MWTALVLIWIFSLSLSESHAASNDPRNFVPNKMWKGLVKRNASVETVDNKTSEDVTMAAASPVTLTKGTSAAHLNSMEVTTEDTSRTDVSEPATSGGAADGVTSIAPTAVASSTTAASITTAASSMTVASSAPTTAASSTTVASIAPTTAASSMTAASSTPMTLALPAPTSTSTGRTPSTTATGHPSLSTALAQVPKSSALPRTATLATLATRAQTVATTANTSSPMSTRPSPSKHMPSDTAASPVPPMRPQAQGPISQVSVDQPVVNTTNKSTPMPSNTTPEPAPTPTVVTTTKAQAREPTASPVPVPHTSPIPEMEAMSPTTQPSPMPYTQRAAGPGTSQAPEQVETEATPGTDSTGPTPRSSGGTKMPATDSCQPSTQGQYMVVTTEPLTQAVVDKTLLLVVLLLGVTLFITVLVLFALQAYESYKKKDYTQVDYLINGMYADSEM
What are the official names of this protein?
Uncharacterized protein C11orf24, Protein DM4E3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Note=Cycles to the plasma membrane via endosomes in a pH sensitive manner. Associated with Rab6-positive vesicles.
Protein: ECPR_KLEP3
Sequence: MEYKCCSDKYIWSAHDSYFYKGLSELILDIDELIYLSQEKIRKDFVFINLNTASLNEFIRRDSEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYVGLSRDIRKELAYVINGRFLRKDIKKDKITDREMKIIRMTAQGMQPKSIARIENCSVKTVYTHRRNAEAKLYSKIYKLVQ
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP plays a dual role in early-stage biofilm development and host cell recognition.  Positively regulates the expression of the ecp operon (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator EcpR.
What is the protein family that this protein belongs to?
Belongs to the EcpR/MatA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_WOLPP
Sequence: MTIILATGGTGGHVFPAITLAKALKVQGHNCILFTDQKTINIESYILPLCKPSGNKLKFLFLLMYSCVLALYQTRKLKPKLIIGFGSYASFPTLLAAKILSIPIVLHEQNTVLGRVNRFFFKSAKLIATSFPETKYAEGSKCVFTGNFVDIEAQGYSRAETVLNVLIIAGSQGANFFDDVVSSVICDLPVEVKERIRVTQQCTKKNINKVKSLYKSEGIDCELSEFFDDMENKLANAHLVISRAGATSIAEITLAERPAVYIPYPHSKDNHQFYNAKHIEDSGAAVMVEQNSNAKKNLGELLVDLLQNCQKLRDMANNTKKTRIRNGVTEFIKAIAQELS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COAX_FINM2
Sequence: MEDILLVIDIGNTNIVLGIFKDDELIFEWRISTDLHKTSDEYALTLRQALEYSNVKKSDVKEAIIGSVVPNLMPTIPKAVKKYLGIEPLIVDEKIKTGIVNKYASPKEVGVDRIINAVSACKKYSTPVIIVDIGTAITFDYITENKEYLGGAIAPGIAISSEALFMKTAKLPKIEIEMPDSVIGDSTVKSMQSGVVFGFIGLIDYIIEKILEEKDKTKDEVTIIATGGFSYLIAKQSKYITIIDKLITLDGLKIINDLNKND
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERF_MOUSE
Sequence: MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFIDMGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPELGAFRGPPLARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAPGGTDKSSGGSGSGGLAEGAGAVAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGVAQCMPLKLRFKRRWSEDCRLEGGGCLSGGPEDEGEDKKVRGDVGPGESGGPLTPRRVSSDLQHATAQLSLEHRDS
What is the function of this protein?
Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter.  May regulate other genes involved in cellular proliferation (By similarity).  Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment.  May be important for regulating trophoblast stem cell differentiation.
What are the official names of this protein?
ETS domain-containing transcription factor ERF.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEOC1_STAAS
Sequence: MKFEKYIDHTLLKPESTRTQIDQIIDEAKAYNFKSVCVNPTHVKYAAERLADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRFDDVQQDIEAVVKVAKGHTVKVIIETVLLDHDEIVKASELTKAAGADFVKTSTGFAGGGATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGATRIGASAGVQIMQGLEADSDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase 1, DERA 1, 2-deoxy-D-ribose 5-phosphate aldolase 1, Phosphodeoxyriboaldolase 1, Deoxyriboaldolase 1.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_MASLA
Sequence: MESVAYILIFTLTIGTLFFAVAFREPPRIERKEK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: NU6C_LOTJA
Sequence: MDLPKTLHDFLLVFLGSGLILGSLGVVLLTNPIFSAFSLGLTLVCISLLYILSNSHFVAASQLLIYVGAINVLIIFGVMFMNGSEYYQDFRLWTVGDGMTLMVCTSIFISLITTIPDTSWYGIIWTTRSNQIIEQDLISTSQQIGIHLSTDFFLPFELISIILLAALIGAIVVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PUR5_CALS8
Sequence: MTTYKDAGVNIEEGYKAVNLIKNIAKETFDSNVITDIGSFGSMYLLNIENSDYILVSGTDGVGTKLKIAFYMDKHDTVGIDCVAMCVNDILCHGAKPLFFLDYIACGKLKSEKVATIVKGVAEGCKIAGCSLVGGETAEMPGFYREEEYDLAGFAVGLVKKDLAICGQDVKEGDILIGLASNGVHSNGYSLVRKVFGIDENPKVLTKVYEELNLSLGEELLKPTRIYVKPVLKVLEKIKIKGIAHITGGGFFENIPRAFPKGFVAVIEKGTWNILPIFRLIQKYSKVDDNEMFSTFNMGIGMVLIVSKDDVETAMEILNEEGINSYVIGTIEKGEGGVVLR
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_ECOL6
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RLMH_STRPS
Sequence: MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTPDKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFSTLTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAJ_CHLRE
Sequence: MKDFTTYLSTAPVIATIWFTFTAGLLIEINRYFPDPLVFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NRDR_SHEB5
Sequence: MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGSRQPFDEEKLQGGMLRAVEKRPVSMDEIEQALSKIKSTLRATGEREVPSEMVGNLMMEQLMSLDKVAYIRFASVYRAFEDVSEFGEAIAKLQK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SYC_RHOP2
Sequence: MALRLYDTLTKEKRAFAPIDPSNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHLYGENHVTYVRNITDVDDKINDRAARDYPGLPLNEAIRKVTEQTERQFHDDVDALGCLRPTVEPRATEHIGEMRTIIDRLVAGGFAYVAADHVLFSPAAMNAANSVLPRYGALANRSLDEMIAGARVDVAPYKRDATDFVLWKPSKPGEPSWPSPAGITMEGRPGWHIECSAMSWKHLGETFDIHGGGIDLVFPHHENEVAQSCCAFQTDRMAQTWMHNGFLQVEGEKMSKSLGNFITIRELLATEKFGGDSWVGEILRFAMIKTHYRSPIDWTVKALDEGHKVLWDWYRDIGDVGPAQQLPGEFIDCLADDLNISSAIAFMHSLRKDKKFAELLATMNFLGFSNAESVLARRPVGVRINLPPAHAEAAVGTVEVLAKPLSKSEIEERIDARTAARARKDFKESDRIRDELAAMGIAIKDGKDADGKPVTTWEIAR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_METLZ
Sequence: MKGLTSKIPRALQTGSKMVCADNTGARVVQIVSVFGYHGVKNRQPKMGLGDLATVTVKKGTPDMKRKLVRAVVVRQKKEFRRPNGLRVSFEENAMILLNENGDPRGTDIKGPVAREVAERFPKVGSMATIII
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NANA_ACTP2
Sequence: MKNLTGIFSALLVAFNEDGSINEQGLRQIIRHNIDKMKVDGLYVGGSTGENFMLSTAEKKEIFRIAKDEAKDQIALIAQVGSVNLQEAVELGKYATELGYDCLSAVTPFYYKFSFAEIKHYYDTIIAETGNNMIVYSIPFLTGVNIGVEQFGELYKNPKILGVKFTAGDFYLLERLKKAYPNHLIWAGFDEMMLPAVALGVDGAIGSTFNVNAPRARQIFELTKQGKLAEALAVQHVTNDLIEGILANGLYLTIKELLKLQGVEAGYCREPMTAKATDKQLEVAKALYAKFL
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_FRATN
Sequence: MKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTRDLGINFVYKSSFDKANRSSINSFRGLGVDKGLEILAKVKKTYNVPVVTDVHEDTPFAEVAEVVDVLQTPAFLCRQTNFILEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKSTGNEQIMVCERGVSFGYNNLVSDMRSLEIMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMETHPNPDEAKSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXS_THEPX
Sequence: MNERYELNKNLAQMLKGGVIMDVTTPEQAVIAEKAGAVAVMALERVPADIRARGGVARMSDPKIIKEIKAAVSIPVMAKVRIGHFVEAQILEALGIDFIDESEVLTPADEMYHIDKWAFKIPFVCGARNLGEALRRIGEGASMIRTKGEAGTGNVVEAVRHMRIINAEIKRLTTLREDELMAAAKELQAPYDLVKYVAQHGRLPVVNFAAGGIATPADAALMMQLGADGVFVGSGIFKSQNPEKMAEAIVKAVTYYDKPEILAEVSEGLGEAMQSIDIRKLDEKDLYASRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: DER_ECO24
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGSPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: HIS6_STRSV
Sequence: MLKKRIIPCLDVKDGRVVKGINFVNLTDVGDPVDAAKAYYEAGCDELVFLDITATHEERDTTVEMVRRVAEQVFIPFTVGGGIRTVEDMKRMLQAGADKVAVNSSALANPQLLADCAEKFGSQCVVLAVDAKKEADGSWHVYLAGGRKDSGRDLLDWVQEAVSLGAGEILLTSMDKDGTKSGFDLPMLEAVSQVVSVPIIASGGAGSSQHILEVFEKTAATGALAASIFHYGQVSIAETKKAMQAAGLEVRI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALG11_PONAB
Sequence: MAAGERSWCLCKLLRFFYSLFFPGLIVCGTLCVCLVIVLWGIRLLLQRKKKLVSTSKNGKNQMVIAFFHPYCNAGGGGERVLWCALRALQKKYPEAVYVVYTGDVNVNGQQILEGAFRRFNIRLIHPVQFVFLRKRYLVEDSLYPHFTLLGQSLGSIFLGWEALMQCVPDVYIDSMGYAFTLPLFKYIGGCQVGSYVHYPTISTDMLSVVKNQNIGFNNAAFITRNPFLSKVKLIYYYLFAFIYGLVGSCSDVVMVNSSWTLNHILSLWKVGNCTNIVYPPCDVQTFLDIPLHEKKMTPGHLLVSVGQFRPEKNHPLQIRAFAKLLNKKMVESPPSLKLVFIGGCRNKDDELRVNQLRRLSEDLGVQEYVEFKINIPFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVVPHEGDITGFLAESEEDYAETIAHILSMSAEKRLQIRKSARASVSRFSDQEFEVTFLSSVEKLFK
What is the function of this protein?
Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.  Catalyzes the addition of the 4th and 5th mannose residues to the dolichol-linked oligosaccharide chain (By similarity).
What are the official names of this protein?
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog, Glycolipid 2-alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: KEFB_SHIBS
Sequence: MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKIGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEPQ_SHEPC
Sequence: MDQLAHHYRAHIAELNRRVAEILSREALSGLVIHSGQPHRMFLDDINYPFKANPHFKAWLPVLDNPNCWLVVNGRDKPQLIFYRPVDFWHKVSDVPDMFWTEHFDIKLLTKADKVAELLPKDTVNWAYLGEHLDVAEVLGFTSRNPDAVMSYLHYHRTTKTEYELECMRRANQIAVQGHLAAKNAFYNGASEFEIQQHYLSAVGQSENEVPYGNIIALNQNAAILHYTALEHQSPAKRLSFLIDAGASYFGYASDITRTYAFEKNRFDELIAAMNKAQLELIDMMRPGVRYPDLHLATHAKVAQMLLDFDLATGDAQGLVDQGITSAFFPHGLGHMLGLQVHDVGGFSHDERGTHIAAPEAHPFLRCTRILAPNQVLTMEPGLYIIDTLLNELKQDSRGLQINWQTVDELRPFGGIRIEDNVIVHQDRNENMTRELGLAD
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.