PharMolix/UniProtQA huggingface dataset:
Protein: PI42B_RAT
Sequence: MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLRVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEETEVEDRAEEEECENDGVGGGLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT
What is the function of this protein?
Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate (PubMed:9685379).  Preferentially utilizes GTP, rather than ATP, for PI(5)P phosphorylation and its activity reflects changes in direct proportion to the physiological GTP concentration.  Its GTP-sensing activity is critical for metabolic adaptation (By similarity).  PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism.  They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3 (By similarity).
What are the official names of this protein?
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta, Diphosphoinositide kinase 2-beta, Phosphatidylinositol 5-phosphate 4-kinase type II beta, PI(5)P 4-kinase type II beta, PIP4KII-beta, Phosphatidylinositol-phosphate kinase IIgamma, PIPKIIgamma, PtdIns(5)P-4-kinase isoform 2-beta.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Nucleus. Cytoplasm. Note=Associated with the plasma membrane and the endoplasmic reticulum.
Protein: HISZ_POLNS
Sequence: MNRWLLPEDITDVMPAEACKVESLRRAVLDLYQSYGYELVAPPILEFLDSLLTGTGSDLNLQTFKLVDQLSGRTLGLRADMTPQVARIDAHLLNRADVTRLCYAGSVAHARTPVGSSAREELQLGAEIYGCATWEADLEAITLLLKTLSVAGLEKVYLDLSHAGILAGILDGQSLDKETIEALYGLLQSKDRPRLGEWSTCLPENVAKALVALIELNGPCAEVLAKAKKELPKHAAIDKALADLERLVSAAANLSANVELSIDLADLRGYQYHSGVMFAAYVDRLPQPIARGGRYDHVGQAFGRPRPATGFSLDLLTLANLSPLNVRKMAITAPWVEDAELSKAIAALRDKGEVVIQVLAGTTLEAAEYQCDRELVKQGSSWEVKKK
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS10_ARTBC
Sequence: MIVRSLLLAGSLLLASVVPASFTLAKSDGPQIKVKEFDKVPTDVHYFEDTDTIILSGKKAELYISTDAAASWNLLEGKSGILYPNKYHTQSAVIYGPNRKHWVTFDAAKTWREFEVPDKLVYGGGFMPFTFHGKDAEKVLISAEECQFMTCRHVTYYTTDGFKTVKRLFEGDMGCFWAVGNPAFGEGEPHLPDKLDDRVFCIWPHATPLDLTRRLVYSDTYFSDRKAVAVEAGGRDIKGVNNMASVKKFLILAASSVGTSEAAIYVSKDAVHWDRADFYGGPKVRGGKFTVLESTNYSIQVNVASRRSRVPIGSLFTSDSTGTSFTMNLDGVNEDKDMITDFEQVSGIQGIFLVNIVENAEEVKKGATREKKLVSRISFDDGRTFKPLKCGDKELHLHSITRPSNIGRTYSSPAPGLVMGIGNTGDKLGTYETGDTFVSNDAGVTWRKALDKAHKYEFGDQGSLLVAVFDEYKDKIFTDEISYSLNHGKDWKKAKLPHRVTALQLTTTPDSTSLQFLLVAEDEKKKFYVMSIDFSDIHERKCEKKDFERWPARLDEKGEPDCLMGHKQFYRRRKADADCFVKEKFKEPLPETEPCQCTKEDFECAAGFLRNKDYECEPHRKVSPPEGKCKNPDDKFMGPSGYRLIPGDDCLKKGGVDLEKEVERTCKDATKAPVSGQISVEKTPFKTKNLNYRYLERSDTSSGDDETVILKTDDGDLFVTRDHGKTWQRGKFKEPISLYIPHKYDNDVIYLLTEGKKAYWSIDRAHTFHSFEGKLPITRTLGTLPLYFHPDHPDWLIWIGGQDCKGKKCTDLAYYSKNRGDEWDLLLRGVGKCMFVGKEGELTADDLIFCSQHEHEDPSKSLRLISSDDMFTKKTSVHFDGKPIVGYAKMSEFIVVATKNGTELSSFTSVDGKTFAHAAFPPNYHIDAEYAYTVLDSSTHSIFLHVTDHPAKMHEFGSILKSNSNGTSYVLSLPNANRNDRDYVDFEKIQVVEGVALANIVINPDEVKAKGQEKKFRSLITHNDGSEWALLSPPKKDVEGKNFDCKVKDKGTDDCALHLHGFTERRENRDSMSSGSAVGLIIGVGNVGSSLTPRAESDTYMSRDAGITWHQIKKGRYQWEFGDQGSIVVVVAEEKPTKVLSYSLDEGETWTDFEFSDKEVTVEDISTVPSDTSRNFILWCRPGSSNEIVAYNVDFSGLKEREKQCVLKKESPEADDYYLWSPKHPMQKDNCLFGHVSMYHRKRPEAKCYNGPKLDRLSGEKKNCQCTRQDYECDYNYERQSDGSCALVKGLKPADPMQICKDDPEAIEYFEPTGYRKLPVSTCEGGHQLDHLVARPCPNKKKEFDEKHPGIGGFGLFFAIFFPVAIATGVGYWAFSKWDGKFGRIRLGESQPESIFSRDSPLISVPVTIVAGTVAVITALPLLFSSLWRSFRGYTRLPGSWWGQRQRPYASRGAFAARRGEYVGVVDDEDELLGAEEFEGDEEEDV
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: SYL_BORDL
Sequence: MSKYDFKKIEKKWQNYWDKHKTYKVNEDPNVPKEKRIYILDMFPYPSANGLHVGHPEGYTATDILTRYKLLNGFNVLHPMGFDSFGLPAENYAIQTGKHPKKITEKNIEKFKEQIKALGFAYDWDREIKTHDVNYYKWTQWIFLQLYKKGLAYTKEIPVWYCPDLGTVLANEEVIQTPDGPRSERGFHKVERKPLRQWLLKITKYAERLIRDLEEVDWPDSVKEMQKNWIGKSTGVEIEFLIKESKEKIKVFTTRPDTIFGVTYLVLAPEHPMVDKITKDELKPIISKYKDKEILKSDLERTSLEKDKTGIFTGAYAINPITKEEIPIWIGSYILGTYGTGAVMSVPAHDERDFEFAKKYNLPIKQVVSQTGTNEVLIKPFTENGISINTPTEFNNLKTIEVKTKVIKWLIENKMGQEKVNYKLRDWIFSRQRYWGEPIPILFDDNLNEIPLNDDELPLTLPDIENYKPSGTGESPLSKIKDWVNVKRNGKIYKRETNTMPQWAGSCWYYIRYLDPHNKKEFANKEKINYWMPVDLYIGGAEHSVLHLLYARFWHKVLYDLGYVNTKEPFRKLINQGMITSFAYQDENGILIPNDEVEKKDNKFFSKKNNKELKQIIAKMSKSLKNIINPDDIIKEYGADSMRIYEMFMGPLTDSKPWNTQGLIGIFRFLNKIWLIKNKELTNETPPKEIISELHKTIKKVTEDIETLNFNTAISTLMIFINELLKHEKNYLKIFRPISIILSPFAPHLGEELWEFMGEQSSIFKNAKWPKYDLNSIIDDTREIVLQVNGKTKDKIMIKKDTDEETLKKIAFNNQKIIQNINNKQIIKIITVKDKLVNIVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_VIBCM
Sequence: MKAGIHPEYKAVNATCSCGNSFVFNSTLGKDTMHLDVCDKCHPFYSGKQRIVDTGGRVERFNKRFGALSAKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: IDI1_HUMAN
Sequence: MPEINTNHLDKQQVQLLAEMCILIDENDNKIGAETKKNCHLNENIEKGLLHRAFSVFLFNTENKLLLQQRSDAKITFPGCFTNTCCSHPLSNPAELEESDALGVRRAAQRRLKAELGIPLEEVPPEEINYLTRIHYKAQSDGIWGEHEIDYILLVRKNVTLNPDPNEIKSYCYVSKEELKELLKKAASGEIKITPWFKIIAATFLFKWWDNLNHLNQFVDHEKIYRM
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase 1, Isopentenyl pyrophosphate isomerase 1, IPP isomerase 1, IPPI1.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ACPS_CHLAD
Sequence: MLYHGVDLVEVRRIRQAVMRYGQRFLARVYTAAERADCEIAPQVMRYEALAARWAAKEACAKALGIGLRGLGAFTVDYPRAGLHDIEVVRDAAGRPTLHLSGVAAQTANALQIRALAVSLSHTDELAIASVVAWVDLSGV
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_STRSV
Sequence: MDNRPIGFLDSGVGGLTVVRELMRQLPHEEVIYIGDSARAPYGPRPAEQIRAYTWQLVNFLLTKDVKMIVIACNTATAVVWEEVKEKLDIPVLGVILPGASAAIKSTASGRIGVIGTPMTVSSDIYRQKIEALSPEMQVESLACPKFVPLVESNELHSSLTKKVVYETLQPLAGRVDTLVLGCTHYPLLRPIIQNRMGPDVKLIDSGAECVRDISVLLNYFEINRSREKQELNHQFYTTANAKSFSEIAESWLRLKVNVEHVSL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: GLNE_XANC8
Sequence: MSQPIPSASPALAALIERAVARVRHALPADAPWPEGVEHPLARVALASDFVVDTLARQPALLAHLAQPDPPPLPVPRLDPAQPQEWAAQLRRYRAAASARLVWRDVLGLDDVDATLAGATTLAETCLQCALQALEQQFSTRHGQVIAEDGSVQRLVVFGLGKLGGGELNFSSDVDLVYAYPQAGQSDGARPLAAEEYFARLGQQLARLLDETTADGFSHRVDLRLRPFGSAGRVALSFNGMDQYFQREGRDWERYAWLKARAVAGDIAAGEAWLETLRPFVYRRYLDFTALDGLRDMKAAITAEVAHHARLDDIKRGPGGIREIEFLAQSLQLIRGGREASLRERRLLPALQALVDLGQIDPPTGQALADAYRFLRRVENRLQMLRDAQTHALPQGEPERERIALGLGYAHWQALLEALAPHRTRVAAEFAELLAPRVHATAPDTLADYWRALPEGDAAPLLGIGLHDPNNAHHMLADFAQSSGVRALSDGARTRLDRVMPALLHAAIRATQPDAALRRVLGLLQATLRRTSYLALLDEQPSALARLVDVLSRSALLAERLAAYPLLLDELLDTRISGPLPDRAALHTACVDTLQIDDTEAALRELNERRLALSFRIALATLDGRQQPVDSTQQLAWLAEAVVQTVLQLARRELVAAHGQVPGGAFAIIGYGSLGGLELGFGSDLDLVFLYDHPREVEASDGKRPLEAGRWFARLAQKVMTLLGAETGAGRLYDIDVRLRPDGGKGALVSSLASYRDYQRDRAWTWEHQALVRARAVAGDAALCEAFVQVRRETLTRVRDPALLHEDVRKMRARMRSELDRSDAGRLDLKQGAGGLVDLEFLLQAGVLGQAAQHPALLLACATPALIDALVQVQWLPAESAAPLHHAHATLVEAGLSCTLDRRPRLVVSTPPIRDACQIVAAIADAQQLRFQPGKGA
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: RL24_BACLD
Sequence: MHVKKGDKVMVISGKDKGKQGVILAAFPKKDRVIVEGVNMVKKHSKPTQANPQGGILNQEAPIHVSNVMPLDPKTGEVTRVGYKVENGKKVRIAKKSGQVLDN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CAS2_METED
Sequence: MAVFLIAYDLVNERRGTHDYQPLWDELKRLGAHRTQFSLWLVSANNTTAEVRQHFQQFVDSNDRIWVTRLRKSQYDYANAIGGTNNWLSNNPPEA
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: TOLB_FRATW
Sequence: MRKIIAGVFIFVFLISNLYAALVAEVTTGVIQKPLVTVVSDNVVDQFPQQVNSVIVADLNHNAKLQANDTIKYEIKQKQNIPWKSLKSDYVVLTKYTNNSYNNYTVEVQILKRNDTSYLQAITYKNINVSLMRTLAHKISNYVYQKLTGNQGFFLTKLAYVKVSNPYARYGRLYELIISDYDGYNKHVVLRQTDNPIATPSWSNDGRYIVYSSYSGGSMGVYTLEIATGKVTRITNYKGINSSPSLSPDGKEIALALSKGYSDQTNIYIMNLSTKALKRITINGINTAPKFSPNGQSIVFTSDREGRPNIYVASVNSKYPQSSILSTKIHQAYEPNYTPDGKNIVFMNQSSRTSGTQIADFNLANGSVTNITNGKADSSPTVSPYGDMVAYISTNTRGYSSLDMVSLDGDNHFNIETADNGNILIQSPSWSPKNF
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MAD3_DANRE
Sequence: MEVNTCNIQVLLQAAEYLERREREAEHGYASVLPFYSNGVSDKRKKQKSKSHSSPGNSRSVHNELEKHRRAQLRHCLEQLKQQVPLSSDSSRNTTLNLLRQAQLHIKKLQEQDERAKLLKDRLRWEQRELRTRLEKLQGGSERMRSDSLGSAVSSERSDSEREDVEIDVESMVWTLEADALGSSHAGVDHSYSTSDHAWL
What is the function of this protein?
Transcriptional repressor.  Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3' (By similarity).
What are the official names of this protein?
Max dimerization protein 3, Max dimerizer 3, Max-associated protein 3, Max-interacting transcriptional repressor MAD3.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL23_CHLMU
Sequence: MKDPYDVVKRHYVTEKAKMLEGLSLGGGEGKKKGSFCKDPKYTFVVAGDATKPMIAEAIEAIYSNKGVKVKKVNTVCVKPQPTRIFRGKRKGRTAGFKKAIVTFVDGHSIG
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: DMPN_PSEUF
Sequence: MATHNKKRLNLKDKYRYLTRDLAWETTYQKKEDVFPLEHFEGIKITDWDKWEDPFRLTMDTYWKYQAEKEKKLYAIFDAFAQNNGHQNISDARYVNALKLFLTAVSPLEYQAFQGFSRVGRQFSGAGARVACQMQAIDELRHVQTQVHAMSHYNKHFDGLHDFAHMYDRVWYLSVPKSYMDDARTAGPFEFLTAVSFSFEYVLTNLLFVPFMSGAAYNGDMATVTFGFSAQSDEARHMTLGLEVIKFMLEQHEDNVPIIQRWIDKWFWRGYRLLTLIGMMMDYMLPNKVMSWSEAWGVYFEQAGGALFKDLERYGIRPPKYVEQTTIGKEHITHQVWGALYQYSKATSFHTWIPGDEELNWLSEKYPDTFDKYYRPRFEFWREQQAKGERFYNDTLPHLCQVCQLPVIFTEPDDPTKLSLRSLVHEGERYQFCSDGCCDIFKNEPVKYIQAWLPVHQIYQGNCEGGDVETVVQKYYHIKSGVDNLEYLGSPEHQRWLALKGQTPPTAAPADKSLGAA
What is the function of this protein?
Part of a multicomponent enzyme which catalyzes the degradation of phenol and some of its methylated derivatives (PubMed:2254259).  DmpL, DmpN and DmpO form the oxygenase component of the complex (PubMed:12186554).  Required for growth on phenol and for in vitro phenol hydroxylase activity (PubMed:2254258, PubMed:2254259).
What are the official names of this protein?
Phenol 2-monooxygenase, oxygenase component DmpN, Phenol 2-monooxygenase P3 component, Phenol hydroxylase P3 protein.
What is the protein family that this protein belongs to?
Belongs to the TmoA/XamoA family.
Protein: CCA_THEAI
Sequence: MIDYQEVLSRYRPTQEEENRLRIISDDIIRKINSICRSRRLRAEAVIVGSYAKGTNLRDGDLDIFIAFDRDYPEEIINTEGLHIGHAVIPNGREKYAEHPYVSGEIGGVKIDVVPCYKMSFGDRKISAVDRTLLHTEYVNGHLDEKGRDEVRLLKIFTKSIGVYGAEARTFGFSGYLCELLVIRFRSFENVIRYFSKAKGRVLIDPDERFRDPMLLIDPVDP
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
Protein: GAG_HV1U4
Sequence: MGARASVLSGKKLDSWEKIRLRPGGNKKYRLKHLVWASRELEKFTLNPGLLETAEGCQQILGQLQPALQTGTEELRSLYNTVAVLYCVHQRIDVKDTKEALNKIEEMQNKNKQRTQQAAANTGSSQNYPIVQNAQGQPVHQALSPRTLNAWVKVVEDKAFSPEVIPMFSALSEGATPQDLNMMLNVVGGHQAAMQMLKDTINEEAAEWDRLHPVHAGPIPPGQMREPRGSDIAGTTSTVQEQIGWMTGNPPIPVGDIYRRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFFKTLRAEQATQDVKNWMTETLLVQNANPDCKSILRALGPGATLEEMMTACQGVGGPGHKARVLAEAMSQVQQTSIMMQRGNFRGPRRIKCFNCGKEGHLAKNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSNKGRPGNFPQSRPEPTAPPAEIFGMGEKMTSPAKQELKDREQTPLVSLKSLFGNDPLSQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: PDRP_ANAMM
Sequence: MRNKAVLDLHLVSDSTCETVIAVARSAVEHFKSLEVNEFVWSLVGSKRQVDKVMLNINPERHNLIMYTVVDDDLRKYLKEKATAQSVRCIPVLAHVIREISCYLQVTKDPNAHPHKLGDEYFNRIDAINYTISHDDGQNLWDIDQADIIIVGVSRTSKSPTSIYLAYRGYRVVNIPLVCSVQLPVDPATIADKLVVGLTIDADRLIQIRRNRLISMKHQENCNYVSYEQVVEEISEMKKICAKNRWPTIDVTQKSVEEIAATIIQFFNRKNNRTGDALY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: IHFB_VIBCM
Sequence: MTKSELIERLCAEQTHLSAKEIEDAVKNILEHMASTLEAGERIEIRGFGSFSLHYREPRVGRNPKTGDKVELEGKYVPHFKPGKELRERVNL
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: SSPB_STAAM
Sequence: MNSSYKSRVFNIISIIMVSMLILSLGAFANNNKAKADSHSKQLEINVKSDKVPQKVKDLAQQQFAGYAKALDKQSNAKTGKYELGEAFKIYKFNGEEDNSYYYPVIKDGKIVYTLTLSPKNKDDLNKSKEDMNYSVKISNFIAKDLDQIKDKNSNITVLTDEKGFYFEEDGKVRLVKATPLPGNVKEKESAKTVSAKLKQELKNTVTPTKVEENEAIQEDQVQYENTLKNFKIREQQFDNSWCAGFSMAALLNATKNTDTYNAHDIMRTLYPEVSEQDLPNCSTFPNQMIEYGKSQGRDIHYQEGVPSYEQVDQLTKDNVGIMILAQSVSQNPNDPHLGHALAVVGNAKINDQEKLIYWNPWDTELSIQDADSSLLHLSFNRDYNWYGSMIGY
What is the function of this protein?
Cysteine protease that plays an important role in the inhibition of host innate immune response.  Degrades host elastin, fibrogen, fibronectin and kininogen.  Blocks phagocytosis of opsonised S. aureus by neutrophils and monocytes by inducing their death in a proteolytic activity-dependent manner.  Decreases surface expression of the 'don't eat me' signal CD31 on neutrophils.  Cleaves host galectin-3/LGALS3, thereby inhibiting the neutrophil-activating ability of the lectin.
What are the official names of this protein?
Staphopain B, Staphylococcal cysteine proteinase B, Staphylopain B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C47 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOZ_AERS4
Sequence: MARVTVEDAVKQVGNRFDLVLVAARRARQIAVQGKDPLVDEENDKPTVIALREIELGLVNNQVMDTQDRYEQQEQEAAELAAVAAIAEGRG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: HDA_ECO5E
Sequence: MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: AROE_ALCBS
Sequence: MSGEKDRADTGLYCVFGNPVSHSRSPEIHHAFAAQHSDPVQYEKREAPLDDFAGAVQAFREAGGLGANVTVPFKEQAFALCDAITERADQAGAVNTLWWDGDQLHGDNTDGAGLVKDIRNNQGWTIRKKRVLILGAGGAVRGVLGPILAQEPTLLRIANRTKEKAEALAGNVMKGEGPPVLGGGLDNLMGQFDLVINAISAGLHGEMPALPDGLLAEGAVAYDMVYGSEPTPFMRWAEQQGAAATADGLGMLVEQAAEAFEIWRGWRPNTAPVMASLR
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: YOUG_BACLI
Sequence: MLADAEWNEKKVLDRRTSRDHVLKGVSGGFAQLCHGKEAPLKRMNPDDWIIYYSPKQNLKDDAPYQKFTAVGEVSDNRVYKVHAGEGFSPYRRKINFLKCRETPIHPFIPNLSFIKNKRHWGYSFRFGHIEISEHDFKLIVKQMVKI
What are the official names of this protein?
UPF0310 protein in gntR 5'region.
What is the protein family that this protein belongs to?
Belongs to the UPF0310 family.
Protein: ARSR2_ECOLX
Sequence: MPEIASLQLFKILSDETRLGIVLLLREMGELCVCDLCTALEQSQPKTSRHLAMLRESGLLLDRKQGKWVHYRLSPHIPSWAALVIEQAWLSQQDDVQAIARKLASANCSGSGKAVCI
What is the function of this protein?
Transcriptional repressor for the ars operon.  ArsR is a trans-acting regulatory protein which controls its own expression.  The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).
What are the official names of this protein?
Arsenical resistance operon repressor.
Protein: NU6C_SORBI
Sequence: MDLPGPIHEILVLFGGFVLLLGGLGVVLLTNPIYSAFSLGLVLVCISLFYFLLNSYFVAVAQLLIYVGAINVLIIFAVMFVNGSEWSKDKNYWTIGDGFTLLLCITIPFSLMTTIPDTSWYGILWTTRSNQIVEQGLINNVQQIGIHLATDFYLPFELISLILLVSLIGAITMARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.