PharMolix/UniProtQA huggingface dataset:
Protein: ATPD_MESM1
Sequence: MISQNNKGYALALFEIANEELKLEQYFQEVKKLNEIINENEDLVKLLSSKEIQLEKKLKILENIFTNHFTVNINNFLKLIITNNLFIYIKSILKIFLDIASKKLNISYGKIYSSKKLDEKIISNLEKFYSDKLSKKVEMLNLIDTTLIKGIRIEIENTIHENSIKNNIKELQKSILEKEQ
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
Protein: MDH_POLNA
Sequence: MSKKPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEVPVEGPQKALKGVMMELDDCAFPLLVEMTAHSDPMTAFKDADYALLVGSRPRGPGMERAELLAVNGAIFTAQGKALNAVASRDVRVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRAASQIAAKTGKAVADIEKLTVWGNHSPTMYADYRFATIGGESVAQMINDQEWNANVFLPTVGKRGAAIIEARGSSSAASAANAAIDHMRDWALGTNGKWVTMGIPSGGEYGIPAETMFGFPVTCENGEYKIVEGLEIDAFSQERINITLAELEGEKAGVAHLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: C82E3_NICTO
Sequence: MVFPVEAIVGLVTFTFLFYFLWTKKSQKPSKPLPPKIPGGWPVIGHLFYFDDDGDDRPLARKLGDLADKYGPVFTFRLGLPLVLVVSSYEAIKDCFSTNDAIFSNRPAFLYGEYLGYNNAMLFLANYGSYWRKNRKLIIQEVLSASRLEKFKHVRFARIQTSIKNLYTRIDGNSSTINLTDWLEELNFGLIVKMIAGKNYESGKGDEQVERFKKAFKDFMILSMEFVLWDAFPIPLFKWVDFQGHVKAMKRTFKDIDSVFQNWLEEHIKKREKIMEVGTEGNEQDFIDVVLSKMSNEYLGEGYSRDTVIKATVFSLVLDAADTVALHINWGMALLINNQNALKKAQEEIDTKVGKDRWVEESDIKDLVYLQAIVKEVLRLYPPGPLLVPHENVEDCVVSGYHIPKGTRLFANVMKLQRDPKLWSNPDKFNPERFIARDIDFHGQHYEYIPFGSGRRSCPGMTYALQVEHLTMAHLIQGFNYRTPTDEPLDMKEGAGITIRKVNPVKVIITPRLAPELY
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (PubMed:17102129).  Catalyzes the demethylation of nicotine to form nornicotine (PubMed:17102129).
What are the official names of this protein?
Nicotine N-demethylase CYP82E3, NND, Cytochrome P450 82E3, NtomCYP82E3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family. CYP82E2 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MIAA_STRT1
Sequence: MKTKLIVVAGPTAVGKTALGIELAERFNGEIISGDSQQVYRQLNIGTAKATPEEQAAAVHHLIDVRDVDESYSAYDFVTEAQAAITDIVSRGKLPIIVGGTGLYLQSLLEGYHLGGKVDQNQVLAYRSELEQLSDQQLFEKIDSSGIEIKEINRRRAIRALELYRFSDNLENTETCYEPFIIGLDDERSLIYDRINTRVDKMVELGLLEEAKWLYDNFPEAQSARGIGYKELFPYFSGEQTLDEALEKLKQNTRRFAKRQLTWFRNRMTVSFYQISSPEYPENVIQDLAIFLNEEEGEK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TX3_THEBL
Sequence: DDCLGMFSSCDPNNDKCCPNRVCRVRDQWCKYKLW
What is the function of this protein?
Blocks Kv4. 2/KCND2 voltage-gated potassium channels probably by shifting the voltage-dependence of channel activation to more depolarized potentials and by binding to the S3-S4 linker region of the voltage sensor domain.
What are the official names of this protein?
Kappa-theraphotoxin-Tb1c, Kappa-TRTX-Tb1c, Theraphotoxin-3, TlTx3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 59 (Tltx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LNPA_BIFL2
Sequence: MTSTGRFTLPSEENFAEKTKELAELWGADAIRNSDGTHLDEAVLALGKKIYNAYFPTRAHNEWITLHMDETPQVYLLTDRILAESDTVDIPLMESFFAEQLKPNRDADPHKYWEVVDRTTGEVVDSANWTLDADEDTVHVSGVAAWHEYTVSFLAYIIWDPVEMYNHLTNDWGDKEHEIPFDIYHPATRKFVFDTFEQWLKDSPQTDVVRFTTFFYQFTLLFDEKRREKVVDWFGCACTVSPRALDDFEAKYGYRLRPEDFVDGGAYNSAWRVPRKAQRDWIDFLSGFVRENVKQLADMSHAAGKEAMMFLGDQWIGTEPYKDGFDELGLDAVVGSIGDGTTTRMIADIPGVKYTEGRFLPYFFPDTFYEGNDPSIEGLDNWRKARRAILRSPISRMGYGGYLSLAAKFPKFVDTVTHIANEFRDIHDRTGGVAAEGELNVAILNSWGKMRSWMAFTVAHALPNKQTYSYYGILESLSGMRVNVRFISFDDVLAHGIDSDIDVIINGGPVDTAFTGGDVWTNPKLVETVRAWVRGGGAFVGVGEPSSAPRFQTGRFFQLADVIGVDEERYQTLSVDKYFPPVVPDHFITADVPVDPAAREAWEQAGYRIPLSGCGGGQSIKPLGGIDFGEPVLNTYPVNENVTLLRADGGQVQLATNDYGKGRGVYISGLPYSAANARLLERVLFYASHNEDKYAAWSSSNPECEVAHFPEQGLYCVINNTDQPQKTTVTLADGTTEDFDLPDSGIAWREA
What is the function of this protein?
Reversibly phosphorolyzes lacto-N-biose to Gal1-P and N-acetylglucosamine (GlcNAc) and galacto-N-biose to Gal1-P and N-acetylgalactosamine (GalNAc).  Involved in the lacto-N-biose I/galacto-N-biose (LNB/GNB) degradation pathway, which is important for host intestinal colonization by bifidobacteria.
What are the official names of this protein?
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase, Galacto-N-biose/lacto-N-biose I phosphorylase, GLNBP.
What is the protein family that this protein belongs to?
Belongs to the glycoside hydrolase 112 family.
Protein: YR660_MIMIV
Sequence: MNKDTDNVEVNIVYKNRTISVPINITMSICALTALLKSYSITGSYHGYNHNYEYHHYHGYNHYNGYNYGKNNKGKIRVGVVSDHKPPFVLTKFPNEMLLLNFRIKEGDRFYVIFEDDYGIPNTHAHDIHESYKQYEPYEPYKSQKNIYIKTLKRAIIADNHRMVEYILDKELVDLHSNKKLYEKCIKLSKIHSRTYIQNLLEVVAL
What are the official names of this protein?
Uncharacterized protein R660.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYGA_ACTSZ
Sequence: MDAKFNVKTFQGMILALQDYWAQQGCTIVQPFDMEVGAGTSHPMTALRAIGPEPMAFAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKMLGFDPTQHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEVTYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFECFNKYEQEAKFLLKQEPRMENDKEIWVETALPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRALTKGVAEAYYASREALGFPGCKK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKC_ECO57
Sequence: MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAATRVSLGSVMACLLLVLTLGLVIGGSAGLIGGRVDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLASRLSGAGHVRVFVDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVTAPTAEWGVMINDARQYIWTQPLQMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHAH
What is the function of this protein?
Involved in a nickel transport system, probably translocates nickel through the bacterial inner membrane.
What are the official names of this protein?
Nickel transport system permease protein NikC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SNF5_TETFL
Sequence: MALSKAFGQKPVKFQLEDGGDFYMIGSEVGNYLRMFRGSLYKRYPSLWRKLASVEERKKIVESSHDHGYTQLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPAYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRSRLGRDKKRTFPLCFDDHDPAVIHENASQSEVLVPIRLDMEIEGQKLRDAFTWNMNEKLMTPEMFAEILCDDLDLNPLAFVPAIPSAIRQQIESYPTDAILEEQTDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGQGGEFVTTIAYSIRGQLSWHQKAYAFSENPLPTVEIAIRNTGAADQWCPLLETLTDAEMEKKIRDQDRNTRRIRRLANTAPGW
What is the function of this protein?
Involved in chromatin-remodeling.  Core component of the BAF (SWI/SNF) complex.  This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation.  Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex) and may play a role in neural development (By similarity).
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1.
What is the protein family that this protein belongs to?
Belongs to the SNF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRHO_BRUO2
Sequence: MSNLPFTVAALYCFAPLPQYESLREPLAQLCCANGIKGTLLLAAEGINGTVAGSAGAIEKLIAHITAIPGLGEPELKYSHASEMPFHRMKVRLKREIVTMGVEGIDPLKSVGTYIAPKDWNALIADENTVVVDTRNDYEYAIGTFEGAIDPQTRTFREFPEWVKQNRDRLEGKKIAMFCTGGIRCEKATAFVKGLGFDDVYHLKGGILKYLEEVPREQSMWNGECFVFDERVAVGHGLAESDVELCRACRRPLTPQDKLSQFFEEGVSCAGCYAERTPEDRARYAERQKQVKLAEKRGANKHIGS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: PARB2_XYLFA
Sequence: MNAKIALTETTNIKEPEPVTTATATKENAFAGASDALGAGIDALFADQGAQYSLIPLDMIQVKTQIRESFEDEENTLEDLAASIKVRGVLQPILLRSNSEGYELIAGERRYRASKLAGLEQIPAYIREMSDEEAEDAQMAENIHRKNLTQIEEAKKIQRDLDKLGSVDAVLEKHQKSRPWLSKMLALLNLPEQAKRLVIENVSADVEVINTVKMVEKINPVKAKELVDDLKKTRGKENARDKAAAVKEEVKPSKKPKADNGEKTPKGRSHEELGQLDVFAGAKFDPFSDAHNGSESPRPLILSPVDVLNRAYTNIFEHGNSPKTILETMPKDEKDRVEGWLHSFYDAGKSVNQDVGRSVIQGFRNGTFSSDGDGAFALVAFLHGVESAEFHLLNVFGSVRK
What are the official names of this protein?
Probable plasmid-partitioning protein ParB.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
Protein: Y1009_YERPE
Sequence: MTIALSEQLTNRFFRYLAVSSQSDAASPTLPSTEGQHKMAQMLAEELRQLGLEDILIDEHATVTARKPGNQPTAPRIGFITHIDTVDVGLSPDIHPQRLRFTGSDLCLNAEQGIYLRTAEHPEILRYQGEEIIFSDGTSVLGADNKAAVTVVMTLLENLTADDCHGDIVVAFVPDEEIGLRGAKALDLARFDVDFAYTIDCCELGEVVYENFNAASAEIDIIGVTAHPMSAKNVLINPIRVAYDIISEFSPQETPEHTEGREGYVWFTDMTANPNSAKLKIAIRDFDNVSFAARKAYIGEVVAKVSAQYPRAKISYSVTDVYSNISNSIGEDKRAIDLIFSSMAELNIEPKVIPMRGGTDGAALSTQGLLTPNYFTGAHNFHSPFEFLPISSFVKSYQLTRTICLSAAKA
What are the official names of this protein?
Peptidase T-like protein YPO1009/y3403/YP_3421.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
Protein: TM138_MOUSE
Sequence: MLQTGNYSLVLSLQFLLLSYDLFVNSFSELLRMAPVIQLVLFIIQDIAILFNIIIIFLMFFNTFVFQAGLVNLLFHKFKGTIILTSVYLALSISLHVWVMNVRWKNSSSFSWTNGLQTLFVFQRLAAVLYCYFYKRTAVRLGDPRFYQDSLWLRKEFMQVRR
What is the function of this protein?
Required for ciliogenesis.
What are the official names of this protein?
Transmembrane protein 138.
What is the protein family that this protein belongs to?
Belongs to the TMEM138 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes to vesicles en route to the base of cilium.
Protein: RL19_ACIF2
Sequence: MNIIDEINQEQMQSVLPAFGAGDTVAVHVKVKEGDRERVQIFEGICIARRNRGLHSAFTVRKISNGEGVERVFPSYSPLVTKVEVKRRGDVRRAKLYYLRDLSGKAARIKEKLG
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ORF32_VZVD
Sequence: MESSNINALQQPSSIAHHPSKQCASSLNETVKDSPPAIYEDRLEHTPVQLPRDGTPRDVCSVGQLTCRACATKPFRLNRDSQYDYLNTCPGGRHISLALEIITGRWVCIPRVFPDTPEEKWMAPYIIPDREQPSSGDEDSDTD
What are the official names of this protein?
Phosphoprotein 32, ORF32 Phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the varicellovirus ORF32 protein family.
Protein: ARGJ_CHLTE
Sequence: MRPVVADPASDAVFWPEGFTLAGINCGIKPTSKDLMLMLCDEPASTASVFTTNLCCAAPVELSKAALSASGGKMRAVICNSGNANAATGAAGMQNARLMAESTAQAFDLNAGEVLVASTGVIGQQLPVEKIAGAMPSLKATSGSTQWCDAAEAIMTTDTFPKAFGVDVKLSGGTARIAGIAKGSGMICPNMATMLAFLGTDATIEPALLQELLAAANAVSFNAITVDGDTSTNDMAAIMASGKGPEVLRGSDNARLFGEALRSVMTMLAQLIIVDGEGATKFVELRVTGAKSNEEARMAAMTVANSPLVKTAIHGEDANWGRIIAAAGRSGASFVQEELSVYFDDEPILKPGLDANFSEERAKEVMSKEEFTITLSLGKGAGRATVWTCDLSHGYIEINGSYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK14_CRYJA
Sequence: MIQSQTYLNVADNSGARKLMCIRVLGAGNRNTANIGDIIIAIIKEAAPNMPLEESEVVRAVVIRTCKELKRSDGMIIRSDDNAAVVIDQKGNPRGTRVFGSVTEELRELNFTKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SELT2_CAEEL
Sequence: MSRSGAIIIGLFFIASIFDVFRAEKEPPAEDSRLEDYLSSELETTAIPTVVNENSHSQDVVDSGFSKDLPKLTILYCVSCGYKQAFNQFYEFAKEKYPGLVIEGGNFSPDFWKGCLAQIVGVAKIGLIAIVITGSNPFEYIGFGYPQILQTAHYNRFSYSLLVFMIGNLFESTLSSTGAFEIFLGDKQIWSKISKERVPTQEEFLNLIDLQLKTIR
What is the function of this protein?
Probably has thioredoxin reductase-like oxidoreductase activity.
What are the official names of this protein?
Thioredoxin reductase-like selenoprotein T homolog selt-1.2.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family. SELT subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Perikaryon. Cell projection, dendrite. Cell projection, axon.
Protein: ARLY_XANP2
Sequence: MSNKMWGGRFTSAPDAIMEEINASIGFDQRLYAQDIAGSKAHAKMLAAQGIVAAQDADRIAEGLDTILSEIEAGNFTFKRELEDIHMNVESRLAELIGASAGRLHTARSRNDQVATDFRLYVRDTLDALDAQLADLQRALAEKALAHAATVMPGFTHLQTAQPVTFGHHLMAYVEMVARDRGRLADARKRLNECPLGSAALAGTSFPIDRDATAKALGFDRPTANSLDAVSDRDFVMETLSAASICAVHLSRFAEEVVIWTSPSFALVKLSDKFTTGSSIMPQKRNPDAAELVRAKAGRIIGALTGILVVMKGLPLAYAKDMQEDKEGAFDAFSALSLVVAASAGMVRDIVPDEKRMEKAAGQGYSTATDLADWLVRALNIPFREAHHITGRIVGLASDRGIALHKLSLDDMQGVDARITQDVFSVLSVVRSVRSRVSYGGTAPTRVRTQAKRWLKKLGVPA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_ZYMMO
Sequence: MTRNSLLNPEAENADPDQALRPRSLDEFIGQQAARENIRVFIEAAKKRQESLDHVLFFGPPGLGKTTLAQIIAREMGVGFRATSGPVIVKSGDLAALLTNLEDGDVLFIDEIHRLQPVVEEVLYPAMEDRALDLMIGEGPSARSVRIDLPHFTLVGATTRQGLLSTPLRDRFGIPVRLQFYSIEELRQVITRAARLLGMEIAPEGAEEIAKRSRGTPRIAGRLLRRVRDFADVAGSKIVDRFIADEALNRLEVDKLGLDLMDRRYLMMIADIYKGGPVGLDTLAAGLSEPRDTVEEVIEPYLIQLGLVARTARGRQLNGLAWRHLGLTDPREAEGKHSEIKNQPGLL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: DEN1A_MOUSE
Sequence: MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQESQWNELLETLHRLPIPDPGVSVHLSVHSYFTVPDSRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFSEEAFVSHYRSGAMKQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDITENGCVSSAEDPLPKTMPSPQAETQDPRLREDRRPITVHFGQVRPPRPHVVRRPKSNITVEGRRTSVSSPEQPQPYRTLKESDSAEGDETESPEQLVREPWGPTPAPPDRAASIDLLEDVFSSLDVEAPLQPLGQAKSLEDLRAPKDLREQPGSFDYQRLDLCRSERGLSMAAALKLAHPYTKLWSLGQDDMAIPSKPSITSPEKPSALLGTSPALPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAGGPLGDFSSEPLQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTIPSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAYAPSILLSSSGFYAPHRSQPNLSALSMPNLFGQIPMGAHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQGLALRPGESPLLPPRPPQSLQPTPQPSVPTQARDPFEDLLRKTKQDVSPSPAPALAPASTSVEQLRRQWETFE
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form.  Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes (PubMed:17182770, PubMed:20159556).  Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P (PubMed:20159556).
What are the official names of this protein?
DENN domain-containing protein 1A, Connecdenn 1, Connecdenn.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Presynaptic cell membrane. Note=Associates to membranes via lipid- binding activity.
Protein: NUP88_MOUSE
Sequence: MAAAVGPLGDGELWQSWLPNHVVFLRLREGVRNQSPAEAEKPAASTSPSCPSLPPHLPTRNLVFGLGGELFLWDAEGSAFLVVRLRGPSGGGVEPPLSQYQRLLCINPPLFEIHQVLLSPTQHHVALIGSKGLMALELPQRWGKDSEFEGGKATVNCSTIPIAERFFTSSTSLTLKHAAWYPSEMLDPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETAVAFDFGPLVTVSKNIFEQKDRDVVAYPLYILYENGETFLTYVSLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAILCLPCVPNILVIATESGMLYHCVVLEGEEEDDQTLEKSWDPRADFIPSLYVFECVELELALKLASGEDDPFASDFSCPIKLHRDPKCPSRYHCSHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELTAEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLSTVHPASPPLLCTQEDAEVAESPLRILAETPDSFEKHIKRILQRSAANPAFLKNCSARSSEKDLAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKLLCDQKRKQLEDLNYCREERVSHLFRKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHAQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVTF
What is the function of this protein?
Component of nuclear pore complex.
What are the official names of this protein?
Nuclear pore complex protein Nup88, 88 kDa nucleoporin, Nucleoporin Nup88.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex.
Protein: GLGB_PSEF5
Sequence: MSFSNKEQGKQQPALLPSAKAIDALVRAEHRDPFAILGPHGDGAGGQFIRAFLPGALSVQVLDRDQQQVLGSLQAGEVPGLFVGHFPEARPYLLRIQWAGGEQVSEDPYSFGPLLGEMDLYLFAEGNHRDLSSCLGAQLTTVDGIDGVRFAVWAPNARRVSVVGDFNIWDGRRHPMRLRHPSGVWELFIPRLQAGEAYKYEILGPQGILPLKADPMALATQLPPDTASRVAPPLTIDWQDQEWMLARGERQRVDAPLSIYELHAGSWQCEVDDLGEVARQYSWAELAERLIPYVKDLGFTHIELMPIMEHPFGGSWGYQPLSQFAPSARYGSPQDFAAFIDACHQAGIGVILDWVPAHFPTDTHGLAQFDGTALYEYGNPLEGFHQDWDTLIYNLGRTEVHGFMLASALHWLKHFHVDGLRVDAVASMLYRDYSRKAGEWVPNRHGGRENLEAIDFLRHLNDVVALEAPGALVIAEESTAWPGVSQRTDQGGLGFAYKWNMGWMHDSLHYIQQDPVYRAHHHNELSFGLVYAWSERFILPISHDEVVHGKHSLIDKMPGDRWQKFANLRAYLSFMWAHPGKKLLFMGCEFGQWREWNHDQQLDWYLLQYPEHRGVQQLVGDLNRLYRQYPPLHDQDDVPQGFQWLIGDDAINSVYAWLRWSKSGEPLLVVANFTPVPRQGYRVGVPVAGRWSELLNSDSQLYAGSNYGNGGEAFSEEQSSHGQALSLVLNLPPLAVLILRPDS
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: HBA_MARPN
Sequence: MVLSAADKTNVKGVFSKIGGHAEEYGAETLERMFIAYPQTKTYFPHFDLSHGSAQIKAHGKKVAAALVEAVNHIDDIAGALSKLSDLHAQKLRVDPVNFKFLGHCFLVVVAIHHPAALTPEVHASLDKFLCAVGAVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: Y2345_CAUVC
Sequence: MSTDARANHRIKSIEIDEESLAAASRDQEQERQVAIFDLLEGNYFEPAEAGDGPYDVRLSLIENRLAFDIASAGHARRHLLSLSPFRGVIKDYFLICDSYYSAIRNSSPQQIEALDMGRRGLHNEGSNLLRERLEGKVKTDLDTARRLFTLICALHWRG
What are the official names of this protein?
UPF0262 protein CC_2345.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: RL23_RICCN
Sequence: MSSYKYYDLIRKPIITEKTTTLSEQNKYAFYVDKFAKKLTLKKAIEEIFKVKVKKVNILNVKGKKKRFKGIIGTQINRKKAIVTLEKDHNIDFAGGIK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: PYRB_BORPE
Sequence: MLNPQLNRHGELIHLLSTEGLPRRIIEQILDLAATFVPAPGQEFPKLPLLHGKSVFNLFFENSTRTRTTFEIAAKRLSADVVNLNIAASSTSKGESLLDTIANLSAMQADLFVVRHGASGAPYLIAQHVAPHVHVINAGDGRHAHPTQALLDMYTIRHHKGDFNQLTVAIVGDVLHSRVARSDIHALTTLGVPEVRVVAPATLLPEGLAQMGVRVCTDMEEGLRDADVVIMLRLQNERMRGALLPSAHEYFKHYGLTQARLALARPDAIVMHPGPMNRGVEIASEVADSGQAVILDQVTFGIAVRMAAMSLVAGVRP
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: SCPB_STAA8
Sequence: MDNHGILESLLFTAGDEGLDEKQLLEILDMSKDQLVELIENYSSHGLMIQRFGMTYVLTTKKEAATYIEQLIEQKSQMKLSQAAMEVLSIIAYNQPLSRSDIELIRSINSDGAVKTLIAKGLVEAKVVNEQRSQQLITTDLFLNVFGISNIEDLPTTEEDDEEMDAFFSNLVNQKGENND
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.