PharMolix/UniProtQA huggingface dataset:
Protein: RODZ_SHIBS
Sequence: MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLLGLEKQAPLRAAKVAPMQSFSLGKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELSSNSEQGQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPAVTAPAPAVDPQQNAVVSPSQANVDTAATPAPTAATTPDGAAPLPTDQAGVTTPVADPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQSPAQ
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: HRG4_CAEEL
Sequence: MTAENRGFCQLICHINVRIGWTIFGIVFGISAILTYAIKFHNWSATATTAIATLFACETLYLYWALKKNTIVNWKSSTFQLMIWPNVFIGLLGLLGCLVCYIIAGITHQGAGSIQGWSLFKCSIYFSKFAAMYGENLWFTGSWSLVITKWTWQNAFFARKYLNKIGTASEDGDIDDDDVEVIKS
What is the function of this protein?
Heme transporter that mediates heme uptake across the plasma membrane.
What are the official names of this protein?
Heme transporter hrg-4, Heme-responsive gene 4 protein, CeHRG-4.
What is the protein family that this protein belongs to?
Belongs to the HRG family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPPH_THIDA
Sequence: MIDREGYRPNVGIILCNARNQVFWGKRVNQHAWQFPQGGINAGETPEQAMFRELEEEVGLLPGHVRILGRTREWLRYDVPPHWTRRDNRGLYRGQKQIWFLLRLTGRDCDVSLRASAHPEFDAWRWNEYWVPMEAVVDFKREVYRLALEELERYLHRDLRYLRQHTRRPGERREVPFDLQLKP
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RL29_XYLFA
Sequence: MNIEQFRAKSVDDLKAHLIELRKEQFSMRMQLAMGQFQKTHEIRRVRRNIARVKYVLSWINRASA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: KRAC_DICDI
Sequence: MSTAPIKHEGFLTKEGGGFKSWKKRWFILKGGDLSYYKTKGELVPLGVIHLNTSGHIKNSDRKKRVNGFEVQTPSRTYFLCSETEEERAKWIEILINERELLLNGGKQPKKSEKVGVADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGVIYRDLKPENLLLTNEGHICMTDFGLCKEGLLTPTDKTGTFCGTPEYLAPEVLQGNGYGKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLEQLLERDPEKRLADPNLIKRHPFFRSIDWEQLFQKNIPPPFIPNVKGSADTSQIDPVFTDEAPSLTMAGECALNPQQQKDFEGFTYVAESEHLR
What is the function of this protein?
Predominantly involved during the aggregation to control cell polarity and chemotaxis.  Phosphorylates talB, gefN, gefS, PI4P 5-kinase and gacQ.
What are the official names of this protein?
RAC family serine/threonine-protein kinase homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
Protein: MEND_PAEAT
Sequence: MTSQDSLTSIGAARIAVTALLDGGVRHVVVAPGSRSAPMAYALAEAEAAGRVRLHVRIDERDAGFTALGLALSTEAPVAVVTTSGTAVGNLLPAVMEANHSAVPVVVISADRPEELHGTGANQTTIQLDLFGDHVRFAVDVPAGDHPQKAVATALYAATGALEDTPPGPVQVNLAFRDPLVPADGDALPAAAGHGVFHYDAGPQALNLPAASGELAERRTVVLAGHDAGPVAEAFARAHGLPLLAEPSSNARFGRNAVGPYRVLLAHFGPDSPTPIERVVLFGRATLSRPVASLLARESVVSAIYQPVPVAWYEEGRRRETPIETLPELADFAGRGSAEWLDSWLLAGAAAQHGLDGVLAGEDLANGPSVGATVWEHSRGQLVLGSSNGIRDVDLAGQPHPEPIATVYANRGLAGIDGTIATATGIALGSGRETTVLLGDVTFLHDAGGLLLGHGEPVPDLRIVVLNDSGGAIFSLLEHGAVEDSGAYGTAVERLFGTPHSVGIGALAAAYGVGHQTVSTTAELAAALKSPLKGRTIVEVRVDRSGLRALHARIKEAVSAAVGQVLTAG
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: DAPA_MAIZE
Sequence: MISPTNLLPARKITPVSNGGAATASPSSPSVAARPRRLPSGLQSVTGRGKVSLAAITLDDYLPMRSTEVKNRTSTDDITRLRLITAVKTPYLPDGRFDLEAYDSLINMQIEGGAEGVIVGGTTGEGHLMSWDEHIMLIGHTVNCFGSRIKVIGNTGSNSTREAVHATEQGFAVGMHAALHINPYYGKTSAEGMISHFEAVLPMGPTIIYNVPSRSAQDIPPEVILAISGYTNMAGVKECVGHERVKHYADKGITIWSGNDDECHDSKWKHGATGVISVTSNLVPGLMHSLMYKGENATLNEKLSPLMKWLFCQPNPIALNTALAQLGVARPVFRLPYVPLPLEKRAEFVRIVESIGRENFVGQKEARVLDDDDFVLISRY
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, chloroplastic, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: OB56H_DROME
Sequence: MKFTLFCIALAAFLSMGQCNPDFRQIMQQCMETNQVTEADLKEFMASGMQSSAKENLKCYTKCLMEKQGHLTNGQFNAQAMLDTLKNVPQIKDKMDEISSGVNACKDIKGTNDCDTAFKVTMCLKEHKAIPGHH
What is the function of this protein?
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid (By similarity).  May function in both olfactory and gustatory systems.
What are the official names of this protein?
General odorant-binding protein 56h.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
What are the subcellular locations of this protein?
Secreted.
Protein: TATA_NEIMB
Sequence: MGSFSLTHWIIVLIIVVLIFGTKKLRNVGKDLGGAVHDFKQGLNEGTDGKEAQKDDVIEHKKDEDKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YR879_MIMIV
Sequence: MKSDNGILMSNINKPNKCYYYCIISEQWDELIYNITGGKITELRGTYVHPKLIIHIASWCNPEYAIKVSEIVLSYHAKEAIKEKEKLLQKKNDKIDELSLKIDKQNKQINKQTATMKKQTKIMKNQTNMMKDQKSTIKEQDKKINELLSKSNEVLGYAKDTNRKITHVVKERVPYSDEPKIEHQFIIMKNNDEPIKPKKGESPKKIYDYTALRIMNKSKSSTMNRYFKDHPDGETILTIDYTPNAMHLWNQCKKELIEDDKIKSSGTSSSSFNLKKGYSENKLKKDIKRIHNLRLKHPE
What are the official names of this protein?
Putative KilA-N domain-containing protein R879.
Protein: NGN1_HUMAN
Sequence: MPARLETCISDLDCASSSGSDLSGFLTDEEDCARLQQAASASGPPAPARRGAPNISRASEVPGAQDDEQERRRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGLPGGGARERLLPPQCVPCLPGPPSPASDAESWGSGAAAASPLSDPSSPAASEDFTYRPGDPVFSFPSLPKDLLHTTPCFIPYH
What is the function of this protein?
Acts as a transcriptional regulator.  Involved in the initiation of neuronal differentiation.  Activates transcription by binding to the E box (5'-CANNTG-3').  Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).
What are the official names of this protein?
Neurogenin-1, NGN-1, Class A basic helix-loop-helix protein 6, bHLHa6, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, NeuroD3.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECA_HELMI
Sequence: MFGFLKNLLDDNARDIRRLQKTVDRINSMEPEWQRLSDADLQHKTVEFRQRLENGESLDDLLPEAFATVREASRRVLGMRHFDVQLIGGMVLHQGRIAEMRTGEGKTLVATLPSYLNALTGRGVHVVTVNDYLAKRDAEWMGRIHRFLGLQVGLIIHGLDFAERREAYAADITYGTNNEFGFDYLRDNMVIQPQHMVQRELHYAIVDEVDSILIDEARTPLIISGQANKPTEKYYAVARIIPRLTKDVDYKVDEKAHSVVLTEEGVSRVEKMLGIDNLADSLDWAHHVNQGLKAHALMRRDRDYVVKDGEVIIVDEFTGRLMFGRRYSEGLHQAIEAKEGLEIQNESQTLATITLQNYFRMYDKLSGMTGTAKTEEPEFMQIYKMDVVQIPTNKPMQRKDLPDVVYRTEEGKFNAVVEEIVQSFRRGQPVLVGTVSIEKSEQLSDKLKRRGVPHQVLNAKHHEKEAEIVKNAGQRGMVTIATNMAGRGTDIILGEGVAELGGLYVIGTERHEARRIDNQLRGRSGRQGDPGQTRFYVSLEDDLMRLFGAENIQGVMDRLGMDDSMPIESGMITRAIENAQRRVEARNFDIRKHVLQYDDVMNQQREVIYDQRKKVLNGENLRDTVFDFIDTLVENMVNRFAGEEKYVENWDLPAMLAYAEETFQIAVTAEDLHEMEKEEVIAFFQEKAQERYSQREQELGLETIRELERIILLRVVDSHWMDHLDAMDHLRHGIGLRAYGQKDPLVEYKYEAYSMFQEMIASVQEEFLRYMFRVNVVVAQAEEEKQEAEAEAEAETVLKNAVENRSDDSLPKQPVKAEPRVGRNDPCPCGSGKKYKKCCGVKG
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: RS16_WOLPP
Sequence: MAVKIRLARFGAKKRPFYRIVVADSRAPRDGRFIERIGQYDPMLPKDNKNRVVVKADRLKHWLSVGAQATERVMWFIKKGIVDLETESKKIEKKKVEKVQGQEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: FABH_BURTA
Sequence: MAQSTLYSRVLGTGSYLPPDRVTNQELADRLAKDGIETSDEWIVARTGIHARHFAAPDVTTSDLAFVAAQRAIEAADVDPQSIDLIIVATSTPDFVFPSTACLLQNKLGIKNGGAAFDVQAVCSGFAYALAMADSFIRTGQHRTALIVGAETFSRILDFKDRTTCVLFGDGAGAVVLSASEEPGILGSALHADGSYSNILCTPGNVNRGVIAGSAFLHMDGQAVFKLAVNVLEKVAVEALSKAALAPEQIDWLIPHQANIRIMTSTCRKLGLPQERMIVTVDEHGNTSAASIPLALDVAVRDGRIKRGQHVLIEGVGGGFTWGASVFRY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARA_ASPCL
Sequence: MFARFCKAIPAKGRAFPSVNASIQSRLMATVRNQRVPHERATFTIRDGPIFHGKSFGARTNISGEAVFTTSLVGYPESLTDPSYRGQILVFTQPLIGNYGVPSAERDQHGLLKYFESPHLQAAGVVVADVAEQYSHWTAVESLGEWCAREGVPAISGVDTRAIVTYLREQGSSLARITVGEEYDADQDEAFTDPEQIHLVRQVSTKAPFHVSAADPQCHVAVIDCGVKENILRSLVSRGASITVFPFDYPIHKVAHHFDGVFISNGPGDPTHCQDTTYHLRRLMETSQVPIFGICLGHQLLALAAGARTIKLKYGNRAHNIPALDMSTGRCHITSQNHGYAVDVDTLPSDWKPYFVNLNDSSNEGMIHKSRPIFSTQFHPEAKGGPLDSSYLFDIYIDSVRKYKANQAAFHPQRDSIPSPLLVDLLAKERVGVQPTIGMQNVQAAAAAAAVAAAA
What are the official names of this protein?
Carbamoyl-phosphate synthase arginine-specific small chain, CPS-A, Arginine-specific carbamoyl-phosphate synthetase, glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_SALG2
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAELVTNLVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLTSVHAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGIHETLDELTTRLAEGLLEAAEDANIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHLMLEEGVYLAPSAFEAGFMSVAHSEEDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C18_CARAU
Sequence: MSLRSSYSVRSSTSQVPVSQMSQMSQMSIKRTTNVPTYRAARSTAAAGQGTRISSASYSGVRSGVGLPSMSSSIHVSATGATGDIMGNEKMAMQNLNDRLASYLRSETLEQANSKLELKIREALEKKGPEVCDYSRFQPIIDDLRRKIFDATSNNARLVLQIDNARLAADDFRVKYDSELSIRQGVEADIAGLRKVIDDTNMNRMNLESEIEALKEELIFLKKNHDNEVMELRNQISHSGVQVDVDAPKGQDLAKIMEEIRSKYEKMALKNQEELKAWHESQITEVQVQVIQNTEALEGARTEVNELRRQIQTLEIELESQRNLKGSLEATLRDTEMRYNMEIESLNAVTMQLEAELTQLRNNIQHQTQEYEALLNLKMKLEAEIATYRRLLDGGDFKLQDALEEQKRVKVMTVTQTLVDGKVVSSSTETKEKKF
What is the function of this protein?
When phosphorylated, plays a role in filament reorganization.
What are the official names of this protein?
Keratin, type I cytoskeletal 18, Cytokeratin-18, CK-18, Keratin-18, K18.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: PPIL3_HUMAN
Sequence: MSVTLHTDVGDIKIEVFCERTPKTCENFLALCASNYYNGCIFHRNIKGFMVQTGDPTGTGRGGNSIWGKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVFGKVIDGLETLDELEKLPVNEKTYRPLNDVHIKDITIHANPFAQ
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  May be involved in pre-mRNA splicing.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 3, PPIase, Cyclophilin J, CyPJ, Cyclophilin-like protein PPIL3, Rotamase PPIL3.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily.
Protein: 6PGL_ECOL5
Sequence: MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEEGLLHEKGRYAVGQGPMWVVVNAH
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: VLTF3_VACCW
Sequence: MNLRLCSGCRHNGIVSEQGYEYCIFCESVFQKCTKVQKKSNFHVSNKLIHLRNVLRRLLSHQCSGEIISELLDIMEKNQISTDDVDANFVSSFLKANERINKKDYKLVFEIINQVKDEKLNLSTEKINEVVEIFKHLVFFCQENTPSKTINYSFFLDKIFDITSVTKNLKPQTVKNYTKNNSNQLVWENFLAHMRSKKRVTMVEDYGHEYVFVDERFSTCSLEV
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from late gene promoters.
What are the official names of this protein?
Viral late gene transcription factor 3, VLTF-3, Trans-activator protein A2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus VLTF-3/OPG127 family.
Protein: NOTQ_ASPVE
Sequence: MPPESERKLACLVCRHRKVACDRGRPQCGLCRKNGFDCEYKTREHRPGLRAGYVSQLEKRVEDLERQMEDVLGRLSQSQPSQPATERDDLATTPSTGRLAPPLCVQNVESTNSPQADTAPVETTALTYELQLVWLQKYQPWFPIMHHTSAVKAVAIWDSPGIPWERKQFLSERLRQEVIVNAMGSLHLRTVQALLTLSILFWGEGKWVQYSNLAAMCKRLSQQLGLPTVAGVAAAQPSKMCSLDAVLSDTKIDHEERLRAFWMIEMLDSIFALGLPSYPPTTAAPLGAILPCSDTAWALQDHFGECVPFHDLQYSSGFSMCISLCTVELAPVHQFQHSVIQTGAMAGGPEWQSAAQRLDERLTIWREEFVAAVFRLINAECPHDARAEMRPAVITLLQSQTSLPEGVGQETEPWPYANHRCMYACENMAAKIRRMEESELESCSPCLVLPIFAAARFYIAVAEHRTPALQSALPIEFYDLRYAVAEICHLLQRWVDRYSSPVLRSV
What is the function of this protein?
Transcription factor that probably regulates the expression of the gene cluster that mediates the biosynthesis of notoamide, a fungal indole alkaloid that belongs to a family of natural products containing a characteristic bicyclo[2. 2. 2]diazaoctane core.
What are the official names of this protein?
Notoamide biosynthesis cluster transcriptional coactivator notQ', Notoamide biosynthesis cluster protein Q'.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNSP8_BOARA
Sequence: MAFLKKSLFLVLFLGIVSLSICEEEKREGEEEEKQEEENEELSEEELRERRALLDKLKSLGKVVGKVAIGVAQHYLNPQQ
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Raniseptin-8, Rsp-8.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
Protein: SYN_STAAB
Sequence: MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEITQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTASAPEGTSELFLTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQYVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGLGLERTVAWISGVEHVRETAPFPRLLNRLYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_ANADF
Sequence: MSAKGAGGARGRGAEGEKIVATNRRARFDFTIEDSWEAGLVLTGSEVKSLREGNVNLSDAYALPRGDELFLVNCRIGEYKQAAHFGHEPLRDRKLLMNRPELDRVKGKIEQRGYTLVPLRLYFKQGWAKVELGLAKGRSHEDRRHAIAERETKREMDREISRRRR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: HNF4A_HUMAN
Sequence: MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
What is the function of this protein?
Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed:30597922).  Activates the transcription of CYP2C38 (By similarity).  Represses the CLOCK-BMAL1 transcriptional activity and is essential for circadian rhythm maintenance and period regulation in the liver and colon cells (PubMed:30530698).
What are the official names of this protein?
Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYV_COLP3
Sequence: MLQQNNEQLLNLLPDKMMEKTFNPTDIEQSLYTSWEEQGYFSPTGEGDSYSIAIPPPNVTGSLHMGHAFQQTIMDTLIRYQRMQGKNTLWQTGCDHAGIATQMVVERKIAAEEDKTRHDYGREGFIDKIWEWKEESGGTIGKQMRRLGNSIDWSRERFTMDDGMSEAVQEVFVRLFEDDLIYRGKRLVNWDPKFHTAISDLEVENKDKKGHMWHLRYPLANGAKTAEGLDYLVVATTRPETMLGDTGVAVNPEDPRYKDLIGKQVLLPLVNRLIPIVGDDHADMEKGTGCVKITPGHDFNDNEVGKRHALPQINILDKDAAILATAEVYDTKGEVCNAYDTGLPSEFAGMDRFVARKAIVAKFDELGLLVEVKDHDLVAPYGDRSGVIIEPLLTDQWYVRVEKLAGPAVDAVKDGQIEFVPKQYENMYFSWMNNIQDWCISRQLWWGHRIPAWYDENEKVYVGRTEEEVRANNDIAADMKLRQDDDVLDTWFSSALWTFSTLGWPKDTEDLKTFHPTDVLVTGFDIIFFWVARMIMMTMHFNKDENGKAQIPFKKIYMTGLIRDENGDKMSKSKGNVVDPLDMIDGISLEDLLQKRTGNMMQPKLAKKIEKLTRKEYPEGIEAHGTDALRFTLTSVATTGRDISWDMKRLEGYRNFTNKLWNASRYVMMNTEEFDCGQSSPEGKAGDMELSLADRWIIGQFEQTVKTVHEAFDTYRFDLASQALYEFTWNQFCDWYLELTKPVLFKENEAQQRGTRHTLVNVLEALLRLMHPIMPFITETIWQRVQPLSDFSKNGDSIMVQAFPQFDESKCDQQAIDDLEWVKQFIIAIRNIRGEMDISPSKELPVLLKNVNDNDQRRLDENEQFLSSLAKLESITVLADDEQGPASASAVVGDLSVLIPMAGLIDKEAELARLDKAIEKLEKEAGRVRGKLGNENFVSKAPAAVIEKEQAKLADAESTLAKILEQKIQIAAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TO6BL_YEAS1
Sequence: MARDITFLTVFLESCGAVNNDEAGKLLSAWTSTVRIEGPEPTDSNSLYIPLLPPGMLKIKLNFKMNDRLVTEEQELFTKLREIVGSSIRFWEEQLFYQVQDVSTIENHVILSLKCTILTDAQISTFISKPRELHTHAKGYPEIYYLSELSTTVNFFSKEGNYVEISHVIPHFNEYFSSLIVSQLEFEYPMVFSMISRLRLKWQQSSLAPISYALTSNSVLLPIMLNMIAQDKSSTTAYQILCRRRGPPIQNFQIFSIPAVTYNK
What is the function of this protein?
Required for formation of the SPO11-mediated double-strand breaks (DSBs) that initiate meiotic recombination.  May mediate the interaction between SPO11 subunits during meiosis.  Also needed for homolog chromosome pairing, synaptonemal complex formation, and for the proper timing of the first meiotic division.  Not required for mitosis and mitotic DNA repair mechanisms.
What are the official names of this protein?
Meiotic recombination protein REC102.
What is the protein family that this protein belongs to?
Belongs to the TOP6B-like family.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with chromatin during prophase. Recruitment to chromatin depends on REC104, SPO11 and SKI8.
Protein: RS13_STRM5
Sequence: MARIAGVNLPAQKHVWVGLQSIYGIGRTRSKKVCEVAGVASTTKIRDLSEPEIERLRAEVGKYIVEGDLRREIGIAIKRLMDLGCYRGLRHRRGLPLRGQRTRTNARTRKGPRKAIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: KTHY_FRATN
Sequence: MQSKFIVIEGLDGAGKSTAISFVRKYLEKNNLAAIYTREPGGTKIAEELRNLVLHNKYDEEIHSDSELLMIYAGRVQHYRNLIAPALEKGINVVSDRFYWSSMAYQGGGRGVELSKIRALNDNFLNGCEPDLVIYLDIDPILGLQRAQKVGSPDRIEKAGLEFFNRTRNVFKDLVKDSDNAIEIDAAKSIQEVEKQIYLILDKHFNFQN
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.