PharMolix/UniProtQA huggingface dataset:
Protein: Y978_MYCBO
Sequence: MHYGLVLFTSDRGITPAAAARLAESHGFRTFYVPEHTHIPVKRQAAHPTTGDASLPDDRYMRTLDPWVSLGAASAVTSRIRLATAVALPVEHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDELVDHGVPPGRRRTMLREYLEAMRALWTQEEACYDGEFVKFGPSWAWPKPVQPHIPVLVGAAGTEKNFKWIARSADGWITTPRDVDIDEPVKLLQDIWAAAGRDGLPQIVALDVKPVPDKLARWAELGVTEVLFGMPDRSADDAAAYVERLAAKLACCV
What are the official names of this protein?
Uncharacterized protein Mb0978c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2161c and Rv3079c.
Protein: PROB_RHOP2
Sequence: MARPKLHDFRRIVVKVGSSLLIDSGAGEVRATWLAALAADIAELHRDGRDVMIVSSGSIALGRSRLKLPRGALKLEESQAAAAVGQIALARTWSEVLGHHGIGAGQILVTLQDTEERRRYLNARSTIAKLLEWRAVPVINENDTVATNEIRYGDNDRLAARVATMASADLLILLSDIDGLYTAPPGSNPDAKLIPVVDSVTAEIEGMAGAAGSELSRGGMRTKIEAAKIATSAGTHMLIASGKIDHPLKAIAGGGPCTWFLTPANPVTARKRWIAGSLEPKGTLTIDAGAVTALRAGKSLLPAGVIRVDGQFARGDAVIVRGPDTHEIGRGLVAYDADDADRIKGRSSPDVMSILGVSGRAEMIHRDDLVVGTAPG
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_SALA4
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQLDEHHAVRTDAGMFDVSHMTIVDLHGSRTREFLRYLLANDVAKLTKTGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPYAIDITVRDDLSLIAVQGPNAQEKAATLFTDQQRHAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIAMPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDEGISPLAANMGWTIAWEPADRDFIGREALEMQREKGHEQLVGLVMTEKGVLRNELPVRFTDAQGNQQEGIITSGTFSPTLGYSIALARVPAGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: H2A2_MEDTR
Sequence: MDASTKTKKGAGGRKGGGPRKKSVTRSIRAGLQFPVGRIGRYLKKGRYAQRVGTGAPVYLAAVLEYLAAEVLELAGNAARDNKKNRIIPRHVLLAVRNDEELGKLLAGVTIAHGGVLPNINPVLLPKKTERSNTVSKEPKSPKPKAGKSPKKA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Probable histone H2A.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CBPYA_PHANO
Sequence: MRVAASALLAGAASAAVAPQQQILKFPSSFSELKEDLWSKPLHNLEESLKSLTGEAKATWDEVATMYPESFDKAAFFSTPKPHTRKHDSEWDHIVKGADVQSVWVENAQGEKEREIDGKLEQFDLRVKKVDPSVLGVDKVKQYSGYLDDNEEDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLMGLFMELGPASVMKDGKLKHNDYSWNANASVIFLDQPVNVGYSYSSGSVSNTVAAGKDIYALLTLFFKQFPEYSKQPFHISGESYAGHYIPVFASEILSHKKRNINLQSVLIGNGLTDGLTQYEYYRPMACGEGGWPAVLDESSCQAMDNAYPRCASLIENCYKSESVWSCVPASIYCNNAMIGPYQRTGQNVYDVRRPCGDNQLCYDEIDYISAFLNKKEVMKAVGAEVSSYDSCNFDINRNFLLQGDWMKPYHRVVPGLLEEIPVLVYAGDADYICNWLGNKAWTEALEWKGHEEYKKAEMKDFKIDGDGKKVGEVKSSGNFTFMKIHAGGHMVPFDQPEASLEMVNRWLSGEFWE
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: RL35_CLOBB
Sequence: MPKMKSHRGAAKRFKKTGTGKLKRAKAFKSHILTKKSPKTKRNLRKGGYVSKSQEKVMKKLLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MXIK_SHISO
Sequence: MIRMDGIYKKYLSIIFDPAFYINRNRLNLPSELLENGVIRSEINNLIINKYDLNCDIEPLSGVTAMFVANWNLLPAVAYFIGSQESRLINHSEMVISYYGGKISKQGEAAIRSGFWHLIAWKENISVGIYERINLLFNPIALEGNYTPVERNLSRLNEGMQYAKRHFTGIQTSCL
What is the function of this protein?
Necessary for the secretion of IPA invasins.
What are the official names of this protein?
Protein MxiK.
Protein: AROA_XYLFA
Sequence: MYCRRSHLKKPSMSHRTHDYWIAHQGTPLHGVLSIPGDKSISHRAVMFAALADGTSRIDGFLEAEDTCSTAEILARLGVRIETPLSTQRIVHGVGVDGLQASHIPLDCGNAGTGMRLLAGLLVAQPFDSVLVGDASLSKRPMRRVTDPLSQMGARIDTSDDGTPPLRIYGGQLLHGIDFISPVASAQIKSAVLLAGLYARNETVVREPHPTRDYTERMLTAFGVDIDVSTGCARLRGGQRLCATDITIPADFSSAAFYLVAASVIPGSDITLRAVGLNPRRIGLLTVLRLMGANIVESNRHEQGGEPVVDLRVRYAPLQGTRVPEDLVADMIDEFPALFVAAAAAEGQTVVSGAAELRVKESDRLAAMVTGLRVLGVQVDETADGATIHGGPIGHGTINSHGDHRIAMAFSIAGQLSVSTVRIEDVANVATSFPDYETLARSAGFGLEVYCDPA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPN1_MOUSE
Sequence: MAAPVAPSEPQASRAPQPPVCLLVLGMAGSGKTTFVQRLTGHLHNKGCPPYVINLDPAVHEVPFPANIDIRDTVKYKEVMKQYGLGPNGGIVTSLNLFATRFDQVMKFIEKAQNTFRYVLIDTPGQIEVFTWSASGTIITEALASSFPTVVIYVMDTSRSTNPVTFMSNMLYACSILYKTKLPFIVVMNKTDIIDHSFAVEWMQDFEAFQDALNQETTYVSNLTRSMSLVLDEFYSSLRVVGVSAVVGTGFDELCTQVTSAAEEYEREYRPEYERLKKSLANAQSNQQKEQLERLRKDMGSVALDPEAGKGNASPVLDPSDLILTRGTLDEEDEEADSDTDDIDHRVTEESREEPAFQNFMEESMAHWKRNK
What is the function of this protein?
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII).  May act at an RNAP assembly step prior to nuclear import.  Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation.  May be involved in nuclear localization of XPA.
What are the official names of this protein?
GPN-loop GTPase 1, MBD2-interacting protein, MBDin, XPA-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: FKB15_MOUSE
Sequence: MFGAGDEDDTDFLSPSGGAKLASLFGLDQATMGHGNEFFQYTAPKQPKKGQGTAAGNQTAPKPAPATTGTSSVLFATAVHAYRYINGQYAKQGKFGAAVLGNHTSREYRILLYISQQQPVTVATIHLNFELMVRPNNYSTFYDDQRQNWSIMFESEKAAVSFNKQVCVAKCNSISSLDAVLCQDLVAAEGPAVETGDSLEVAYTGWLLQNHVLGQVFDSTANKDKPLRLKLGSGKVVKGLEDGLLGMKKGGKRLIITPSACAAGSEGVIGWTQPTDSILVFEVEVRRVKFARDSGSDGHSVSSRDSAAPSPIPASDSLSADPVVTPLPLPLKPGEPGLRSKSNSLSEQLTVNSNPDTVKAKLISRMAKMGQPMLPILPPQLDSNDSETEDATVLRGAGQSLVTPSIQPSLQPAHPVLPQMASQAPQPSGSGLQTPSAALMQAVSLDSHSAVSGNAQNFQPYAGVQAYAYPQTPSVTSQLQPVRPLYPAPLSQAPHFQGSGDMMSFLMTEARQHNTEIRMAVNKVADKMDHLMTKVEELQKHSSGNSMLLPSMSVTMETSMIMSNIQRIIQENERLKQELLEKSSRIEEQNDKISDLIERNQRYVEQSNLMMEKRNNSLQTATENTQARILHAEQEKAKVTEELAAATAQVSHLQLKMTAHQKKETELQLQLTDNLKETDLLRGHVTRLQADLSELREASEQTQTKFKSEKQSRRQLELKVTSLEEELTDLRAEKTSLEKNLSERKKKSAQERCQAEAEMDEIRKSHQEELDRLRQLLKKARVSTDQAAAEQLTLAQAELQSQWEAKCEQLLASARDEHLQQYREVCAQRDAHQQKLALLQDECLALQAQIAAFTEQKEHMQRLEKTKSQAPAGRAAADPSEKVKKIMNQVFQSLRGEFELEESYDGGTILRTIMHTIKMVTLQLLNHQEEEEEEEEEEEEEKKPLRPSLEQPGPATPGMPPAPPSGETQEAPEVLPEQVVGETTPLPLQALPTPENGAQTRKGEPAEAEVPSEIKDSSLPPQPAGIPAHRVLGPPTSIPPKPPGPVTMDSESEEMLAADQRTVQPNGLLGEEHVREVATDGLLQGNSRRLSLTPDPEKGEPPALDPESQGGEAQPPECKQAEDVSSSGPRETLLDTELASAAAGTSLRHNQDSQHCSLSGDEEDELFKGATLKVPRPTAQPEEEDEDEVSMKGRPPPTPLFGDDDDDDDDDIGWLG
What is the function of this protein?
Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement (By similarity).  May be involved in the cytoskeletal organization of neuronal growth cones.  Seems to be inactive as a PPIase.
What are the official names of this protein?
FK506-binding protein 15, FKBP-15, 133 kDa FK506-binding protein, 133 kDa FKBP, FKBP-133, WASP and FKBP-like, WAFL.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, axon. Early endosome. Note=Present in axons and neuronal growth cones.
Protein: CRTC_CERS4
Sequence: MIGFIGSVFSPWYRWSGRKEPQNHCCLNVATYGPGGRFTMTDRGRAALRQSPDTLTVGPSRMHWTGTQLIVEVNEISSPPLVSPVKGRIVLTPTGITDVEVTLKDDGSHIWRPFAPTARIEVDLTQGHRWHGHGYFDANFGTAALEADFRFWTWGRYPVADGAACFYDATRRDGSRLELGLHVAADGRARLIQPPPEARFARSRWLVERHTPADPGTRPRQVMSMLDAPFYSRAMVETTVFGQKTVGVHEALDLRRFRSPLLMPMLAVRVPRRPGWSFS
What is the function of this protein?
Involved in the biosynthesis of carotenoids spheroidene and spirilloxanthin.  Catalyzes the hydration of neurosporene to the corresponding hydroxylated carotenoids 1-HO-neurosporene and that of lycopene to 1-HO-lycopene (By similarity).
What are the official names of this protein?
Acyclic carotenoid 1,2-hydratase, Hydroxyneurosporene synthase, Lycopene hydratase, Neurosporene hydratase.
What is the protein family that this protein belongs to?
Belongs to the CrtC hydratase family.
Protein: RIR2_MYCGE
Sequence: MAANNKKYFLESFSPLGYVKNNFQGNLRSVNWNLVDDEKDLEVWNRIVQNFWLPEKIPVSNDIPSWKKLSKDWQDLITKTFTGLTLLDTIQATIGDICQIDHALTDHEQVIYANFAFMVGVHARSYGTIFSTLCTSEQINAAHEWVVNTESLQKRAKALIPYYTGNDPLKSKVAAALMPGFLLYGGFYLPFYLSSRKQLPNTSDIIRLILRDKVIHNYYSGYKYQRKLEKLPLAKQKEMKAFVFELMYRLIELEKDYLKELYEGFGIVDDAIKFSVYNAGKFLQNLGYDSPFTAAETRIKPEIFAQLSARADENHDFFSGNGSSYVMGVSEETNDDDWNF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit beta, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: ATO7B_XENLA
Sequence: MKSDSPVHGESHTECQSPCPLSCMPARLEGSTKRRLAANARERRRMQGLNTAFDSLRKVVPQWGEDKKLSKYETLQMALSYIMALSRILTEAERYSRTDPGEWTKMHFDHIQEEQCLSYMGVRCPRDCDRYLPQTFSH
What is the function of this protein?
Transcription factor that binds to DNA at the consensus sequence 5'-CAG[GC]TG-3' (By similarity).  Positively regulates the determination of retinal ganglion cell fate and formation of the optic nerve and retino-hypothalamic tract (PubMed:9390513).  Required for retinal circadian rhythm photoentrainment (By similarity).  Plays a role in brainstem auditory signaling and binaural processing (By similarity).  Regulates the differentiation of olfactory receptor neurons (PubMed:12454929).  During retinal neurogenesis, activates the transcription of several genes such as brn3d, coe3, cbfa2t2, glis2, elrC and xgadd45-gamma (PubMed:11401395, PubMed:16112102).
What are the official names of this protein?
Transcription factor Atoh7-b, Atonal bHLH transcription factor 7-B, Helix-loop-helix protein xATH-5-B, Protein atonal homolog 5-B, xAth5-B, Protein atonal homolog 7-B.
What are the subcellular locations of this protein?
Nucleus. Perikaryon. Cell projection, axon.
Protein: RUTC_ECOS5
Sequence: MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: RECA_NEILA
Sequence: AIMKMDGSQQEENLEVISTGSLGLDLALGVGGLPRGRIVEIFGPESSGKTTLCLEAVAQCQKNGGVCAFVDAEHAFDPVYARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGIDMVVVDSVAALVPKAEIEGDMGDSHVGLQARLMSQALRKLTGHIKKTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFYSSVRLDIRRTGSIKKGEEVLGNETRVKVIKNKVAPPFRQAEFDILYGEGISWEGELIDIGVKNDIINKSGAWYSYNGAK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UP06_FRUSA
Sequence: AQLQNPVGYELQHK
What are the official names of this protein?
Unknown protein 6 from 2D-PAGE.
Protein: MSCL_XANOM
Sequence: MGMVSEFQQFAIRGNVIDLAVGVVIGAAFGKIVTALVEKIIMPPIGWAIGNVDFSRLAWVLKPAGVDATGKDIPAVAIGYGDFINTVVQFVIIAFAIFLLVKLINRVTNRKPDAPKGPSEEVLLLREIRDSLKNDTLKSG
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRPF_ALKPO
Sequence: MFQSILMIVLVVMSISLFVCFIRTLIGPTMSDRIVALDTFGINLIGFIGVIMMLQETLAYSEVVLVISILAFIGSIALSKFIERGVVFDRG
What is the function of this protein?
Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance.  Na(+)/H(+) antiport consumes a transmembrane electrical potential, and is thus inferred to be electrogenic.  Does not transport K(+), Ca(2+) or Mg(2+).
What are the official names of this protein?
Na(+)/H(+) antiporter subunit F, Mrp complex subunit F, Multiple resistance and pH homeostasis protein F.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MDTB_ECOL6
Sequence: MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFARHEEEA
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CM3M_CONRE
Sequence: IVRCCSATCKXSCVCCF
What are the official names of this protein?
Conotoxin reg3m.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_PASMU
Sequence: MAKLTKKMKSIKAAVDSTKAYEINEAIAVLKQFATAKFVESVDVAVNLGIDPRKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKEAGADLVGMEDLAELVKKGEMNFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPNVADAVKNAKSGQVRYRNDKNGIIHTTIGKVNFSEEQLKENLQALLAALAKAKPTTSKGVFIKKVSLSTTMGAGVAIDQASL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ACT3_TOBAC
Sequence: AGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIASNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFSVPAMYVAIQAVLSLYASGRTTGTGIVLDSGDGVSHHVPIYEGYALPHAILRLDLAGRDLTDSLMKILTERGYMFTTTAEREIVRDMKEKLAYVALDYEQELETARSSSSIEKNYELPDGQVITIGAERFRCPEVLFQPSMIGMEAAGIHETTYNSIMKRDVDIRKDLYGNIVLSGGSTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTLQQV
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin-54.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LEUC_SHEWM
Sequence: MAKTLYEKVWDSHVVVANEGEAPLIYVDRHLVHEVTSPQAFSGLKVAGRRLRAPEKTFATMDHNTSTKSASLDALSPMARIQVETLQDNCKEFGIKLYDIHHKNQGIVHVMGPELGITLPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVMATQTLRQNKAKTMKIEVKGHVTPGITAKDIVLAIIGKIGMDGGTGYVVEFCGEAIEALSMEGRMTVCNMAIEMGAKAGMIAPDATTAEYLKGREFAPKAESWEQAIEAWSELKTDADAVFDSTVILEAADIAPQLTWGTNPGQVVAIDGVVPNPQDEPNATVKASIEKALEYVALSAGTSMKDVSINKVFIGSCTNSRIEDLRDAALHAKGKHVAEGVTAIVVPGSGLVKEQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNDDRLEAGDRCASTSNRNFEGRQGRGSRTHLVSPAMAAAAAVAGHFVDIRQTL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: NOTUM_SCHMD
Sequence: MKSYLILNTLLLSLLKINGFSKSSWFSSKTSLIFDRINKLNDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDRLKRRLKKKLKRKVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEKKKIKKKVQKNPKLIKTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLLYCSSR
What is the function of this protein?
Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway (PubMed:21566195).  Acts by specifically mediating depalmitoleoylation of WNT proteins.  Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors (By similarity).  Promotes head regeneration following amputation by inhibiting the Wnt signaling pathway.
What are the official names of this protein?
Palmitoleoyl-protein carboxylesterase NOTUM, Smed-notum.
What is the protein family that this protein belongs to?
Belongs to the pectinacetylesterase family. Notum subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPP_AZOBR
Sequence: MLIDQYLDAALLGLIEGLTEFLPVSSTGHLIIFDTLLGFEGPPGKVFEVVIQLGAILAICTVYFARLWKVVTGLKDDPGARHFAMAVILAFLPAMVLGAALHGVIKAVLFNPTVVSIALILGGVAILMAERLVPAPRYHQIERFPAPLALKIGLCQCLALVPGVSRSGATILGSLLMGVDRRTAAEF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin (By similarity).
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COBQ_AZOC5
Sequence: MARALMFQGTGSDVGKSLLVAGLARAFADRGLKVRPFKPQNMSNNAAVTADGGEIGRAQALQARAARVPLSVHMNPVLLKPQSEVGAQVVVQGRVVGSAKAAAYQQMKAGLLPSVLESFRRLKTEADLVLVEGAGSASEVNLRANDIANMGFARAADVPVVLIGDIDRGGVIASLVGTKTVLDPADAAMIQGFIVNRFRGDPALFGSGMDLIAGHTGWAALGLVPFYTGAARLPAEDALGVAGPQAPKPGAKVRIAVPILPHVANFDDLDPLDAEPGLEVRRIRPSDVLPTDTDLVLLIGSKATIADLAALRAGGLHHDIQAFARRGGRVLGLCGGYQMMGEHLSDPDGVEGPPGSTEGLGLLKVGTVMTGEKRLVAVTGTSRLGAPFSGYEMHIGATEGADTARPFAELDGAGAEGAVSADGRIMGTYVHGLFGDDRQRAALMGLLGAGPAQVAYEAGVEEALDGLAAHLSAHLDLDRLLSLAR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: NADA_CORGL
Sequence: MPDVYGPGASQNDPIPAHAPRQQVLPEEYQRASDDELHRRIREAKDTLGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPEAEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADMADLDSVEDCWEQLTSIYGDDTLIPVTYMNSSAALKGFVGEHGGIVCTSSNARSVLEWAFERGQRVLFFPDQHLGRNTAKAMGIGIDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHVIVHPESPMPVVDAADSSGSTDFIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCLDPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESVAAPARVALERMLSVVPAAPVTPSSSKDA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_SHEHH
Sequence: MPLLDSFTVDHTRMNAPAVRIAKSMVTPKGDTITVFDLRFCVPNKEILSERGIHTLEHLFAGFMREHLNGDSVEIIDISPMGCRTGFYMSLIGAPTESIVADSWLAAMQDVLKVAVQSDIPELNEYQCGTFEMHSLEQAQEIARNIIASGINVNRNDDLSLSEEILKGL
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.