PharMolix/UniProtQA huggingface dataset:
Protein: BDNF_AILFU
Sequence: MTILFLTMVISYFGCMKAAPMKEANVRGQGSLAYTGVRTHGTLESMNGPKAGSRGLTSLADTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR
What is the function of this protein?
Important signaling molecule that activates signaling cascades downstream of NTRK2.  Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2.  Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD).  Binding to NGFR and SORCS2 promotes neuronal apoptosis.  Promotes neuronal growth cone collapse.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted. SUBCELLULAR LOCATION: [BDNF precursor form]: Secreted. Note=A proportion of BDNF is secreted as immature precursor (proBDNF).
Protein: LPQN_MYCTU
Sequence: MKHFTAAVATVALSLALAGCSFNIKTDSAPTTSPTTTSPTTSTTTTSATTSAQAAGPNYTIADYIRDNHIQETPVHHGDPGSPTIDLPVPDDWRLLPESSRAPYGGIVYTQPADPNDPPTIVAILSKLTGDIDPAKVLQFAPGELKNLPGFQGSGDGSAATLGGFSAWQLGGSYSKNGKLRTVAQKTVVIPSQGAVFVLQLNADALDDETMTLMDAANVIDEQTTITP
What is the function of this protein?
Is also a virulence factor required for intracellular survival (PubMed:30118682).  Associates with CBL, a host ubiquitin ligase, and probably blocks the normal functions of CBL and disturbs CBL-mediated antibacterial activity (PubMed:30118682).  Interaction counteracts antibacterial defense but causes a reciprocal enhancement of antiviral defense (PubMed:30118676, PubMed:30118682).
What are the official names of this protein?
Lipoprotein LpqN.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Secreted.
Protein: 366R_IIV6
Sequence: MPLLRKRSLSPKRRSPRRSPTRSPRRSPTRSPRRSPRRSPRRSPKSMTVQSIAFPKNWKRSHITSWLKNHNYHPIKEDSTANFIRFRILPPHRNAIFATKILPNDIHLIMMRNY
What are the official names of this protein?
Uncharacterized protein 366R.
Protein: SYT1_BOVIN
Sequence: MVSESHHEALAAPPVTTVATVLPHNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVKK
What is the function of this protein?
Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity).  May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity).  It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.  A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported.  It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.  Plays a role in dendrite formation by melanocytes (By similarity).
What are the official names of this protein?
Synaptotagmin-1, Synaptotagmin I, SytI, p65.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass membrane protein. Cytoplasm.
Protein: PYRG_STAES
Sequence: MTKFIFVTGGVVSSLGKGITAASLGRLLKDRGLKVTIQKFDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTAGKVYSHVLKKERRGDYLGGTVQVIPHITNEIKERLLLAGESTNADVVITEIGGTTGDIESLPFLEAIRQIRSDLGRENVMYVHCTLLPYIKAAGEMKTKPTQHSVKELRGLGIQPDLIVVRTEYEMTQDLKDKIALFCDIKKESVIECRDADSLYEIPLQLSKQNMDDIVIQRLQLNAKYETQLDEWKHLLNTVNNLDGKITIGLVGKYVSLQDAYLSVVESLKHAGYPFKKDVVVKWIDSSEVNDDNVEAYLSDVDGILVPGGFGFRASEGKIAAIRYARENNIPFFGICLGMQLATVEFARHVLGYEGAHSAELDPSTPYPIIDLLPEQKDIEDLGGTLRLGLYPCHIKEGTLAEKIYNKNDIEERHRHRYEFNNEFREQLESNGMVFSGTSPDGRLVEIIEIPKNDFFIACQFHPEFLSRPNRPQPIFKSFVEAALNYQQK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: LRC40_PONAB
Sequence: MSRLKRIAGQDPRAGFKEGGRDCGTSVPQGLLKAARKSGQLNLSGRNLSEVPQCVWRINVDIPEEANQNLSFGATERWWEQTDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELQNLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQFSNLEDLDLSNNRLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLQSLERLDLSNNDISSLPYSLGNLHLKFLALEGNPLRTIRREIINKGTQEVLKYLRSKIKDDGPSQSESATETAMTLPSESRVNIRAIITLKILDYSDKQATLIPDEVFDAVKSNIITSINFSKNQLCEIPKRMVELKEMVSDVNLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEVESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILMKGTAGILEYLRDRIPT
What are the official names of this protein?
Leucine-rich repeat-containing protein 40.
Protein: AMPA_BURL3
Sequence: MDFSIKGCDWSKGEAKGFLTGKSDCIVLGIFEAQTLSGAALDIDTATKGLISRVIKAGDMDGKRGKTLFLHEVSGIGASRVLLVGLGKQDAFNQKAYNDAVTAAWRALLATKVVQVTFTLAQLPVDERSSDWGVRAAILALRNETYRFTQMKSKPEPASHTLKRVVFSVDPSDEKAAKVAVKQAVALANGMDLTRDLGNLPGNVCTPTYLGNTAKKIAKDWGLKAEVLGLKQIQALKMGSFLSVARASVEPPQFIVLHYQGAAAKAAPVVLVGKGITFDTGGISLKPGEGMDEMKYDMCGAGSVLGTMRAVAEMGLKINVVAIVPTCENMPGGNATKPGDIVTSMKGLTIEVLNTDAEGRLILCDALTYAERFKPAAVIDVATLTGACVIALGGHNSGLFSTDDALAGELLDASREANDPAWRMPLDDEYQDQLKSNFADLANIGGRPAGAVTAACFLSRFTESYPWAHLDIAGTAWKGGAAKGATGRPVPLLAQFLIDRAGQ
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBI_PROMS
Sequence: MLALKISVYTIVFFFVGIFLFGFLASDPTRTPNRKDLESPQD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MUKB_SHIDS
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKVGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELYTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVEQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALCQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFSSSQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAACESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEPEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRRLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRILNQGLQNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: TM14C_BOVIN
Sequence: MPKDSGPLVPLHWLGFGYAALVASGGIIGYAKAGSVPSLAAGLLFGGLAGLGSYQLSQDPKNIWLFLVTSGTLAGIMGMRFYNSRKFMPAGLIAGASLLMVVKLGISALSKPHQ
What is the function of this protein?
Required for normal heme biosynthesis.
What are the official names of this protein?
Transmembrane protein 14C.
What is the protein family that this protein belongs to?
Belongs to the TMEM14 family.
Protein: ARNF_ECOSM
Sequence: MGLMWGLFSVIIASAAQLSLGFAASHLPPMTHLWDFIAALLAFGLDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFSLKALLGVACIMSGLMLIFLPTTKQRY
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL23_TETTS
Sequence: MAAARGRGGQVGTKAKVSLGLPVGAVMNCADNSGAKNLYTIACFGIKGHLSKLPSASIGDMILCSVKKGSPKLRKKVLQAIVIRQRRPWRRRDGVFIYFEDNAGVIANPKGEMKGSQITGPVAKECADIWPKVASNAGSVV
What are the official names of this protein?
60S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PPME1_NEUCR
Sequence: MSELQKQWAKARLGSQALGQPPAEMPITTTMPEFNEADEDKEMAGPSPGGFPFDDDSSSASSVSSTGTVIPSPGRALFARPQGFASRSMDPIPWTTYFERELFLKEEAGPDSGSRTSNKNKPTSITYHAYLTSPVGKGPLFVTHHGAGSSGLSFAVLSSEIRKRLPNAGILSLDARGHGSTTVTAASSVPGEGDETTGQAPPPLDLSLSTLASDLFTVIQLTRTAMHWPELPPIILVGHSLGGAVVTELAKSYRLGPSLLGYAVLDVVEGCAMDALQSMQTYLSTRPQGFASLKDGIDWHVRSRTIRNSTSARTSVPGLLAPVEELQRPELQQLPRGVAGTQGTAKPWRWKTDLAATQPFWEDWFVGLSKKFLEARGGKMLLLAGTDRLDTELTIGQMQGKYALQVFPEAGHFIHEDLPEKTAIALVDFHRRNDRSQLVLPPKVSDLLAQGKKV
What is the function of this protein?
Demethylates proteins that have been reversibly carboxymethylated.  Demethylates the phosphatase PP2A catalytic subunit (By similarity).
What are the official names of this protein?
Protein phosphatase methylesterase 1, PME-1, Pectin methylesterase 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: ATPG1_ARATH
Sequence: MACSNLTTMWVSSKPSLSADSSSLSFRSVLKCPTNTSSPPSRASSVSPLQASLRELRDRIDSVKNTQKITEAMKLVAAAKVRRAQEAVVNGRPFSETLVEVLYNINEQLQTDDVDVPLTKVRPVKKVALVVVTGDRGLCGGFNNFIIKKAEARIKELKGLGLEYTVISVGKKGNSYFLRRPYIPVDKYLEAGTLPTAKEAQAVADDVFSLFISEEVDKVELLYTKFVSLVKSEPVIHTLLPLSPKGEICDINGTCVDAAEDEFFRLTTKEGKLTVERETFRTPTADFSPILQFEQDPVQILDALLPLYLNSQILRALQESLASELAARMSAMSSASDNASDLKKSLSMVYNRKRQAKITGEILEIVAGANAQV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain 1, chloroplastic, F-ATPase gamma subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GRID2_HUMAN
Sequence: MEVFPFLLVLSVWWSRTWDSANADSIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTLSVRPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENNINKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNMEISNLYIYDTVLLLANAFHKKLEDRKWHSMASLSCIRKNSKPWQGGRSMLETIKKGGVSGLTGELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNMRGVVLRVVTVLEEPFVMVSENVLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRAEKTVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTIGNTVADRGYGIALQHGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQCDLYSSVDTKQKGGALDIKSFAGVFCILAAGIVLSCFIAMLETWWNKRKGSRVPSKEDDKEIDLEHLHRRVNSLCTDDDSPHKQFSTSSIDLTPLDIDTLPTRQALEQISDFRNTHITTTTFIPEQIQTLSRTLSAKAASGFTFGNVPEHRTGPFRHRAPNGGFFRSPIKTMSSIPYQPTPTLGLNLGNDPDRGTSI
What is the function of this protein?
Receptor for glutamate.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.  Promotes synaptogenesis and mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the beta-NRX1-CBLN1-GRID2 triad complex (PubMed:27418511).
What are the official names of this protein?
Glutamate receptor ionotropic, delta-2, GluD2, GluR delta-2 subunit.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRID2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi- pass membrane protein.
Protein: PLDA_DICDI
Sequence: MSNNSKSPPNEQHQQQPHPPDVLVQLTESFQHFFQSLSPQYQSMTSLPSINKDSYTSVGSAPTTNNNSNSNSNSNSSNRSLNNSGSSNSGGGGSNSNKKVNNNNNNNNNNNNNNLQSPTQSQFPYHYQYSSKALHDFEEKRKLLIEQLKSVKINLDTQCDDDPISFIKIRMELTKVKTSLETELKSLDELLHTTSEVEEPNPTPIDSITSLLTMIMPSSISNSVTNNTPSSATPLTLSNNNNYTSSSLATSPTTNSSSSSSSSSSSSSTHYYNSSISSNSLSSNLPPSSIPILNTSNNKNSYPNSIIPQGTPLDNPDPNLPRFPQRDHISVKLYVDCDDYFAASAQAIENATREVFITAWFLSPEVYLIRFPSLDERYRLDNLLKRKAMQGVKIFIILWDETKIATFKGSKRAKDKLEELHTNIKVIKHPPIIPIYWSHHQKTLIIDQEIAFVGGVDFCFGRFDTWCHHLIDVNSTLWKGKDYYNPILGDMGDILVPFEDSVDRKKIPRMPWHDVMAGVNGLAARDVALNFILRWNHHKDDYYPQLYFDTTPLSPVGTSQCQLLRSMDEWSGGGRIERSIHTAYVQAIEDANHYIYIENQNFVSTHAPNVWNQISFEIVKRIKRAIRKKEVFRVFIVIPCQQDGKVEETQIKGLMHWQYSTIIRGENTIMKLLRRDCPDVDLTEYICFLSLRTHAFLEGTFVTEQIYVHSKLMIVDDRTIIVGSANINDRSLIGERDSELAFIIRDEIDTIQTKMNGQDYIASRLVFNFRLRLWKEHLGLLPQINYPPHDQINNDINNIVNLNNNNNSNINNNINNNNNEINNNNNNNNNNNSNEINNNNSDGILNNSNSFHHGSVSDNLPPLNPSSNLNSSNKKLPTTTTAAAAATTTTTTTTTTTTTNGTGTTNKQKTSHHRSNSFQGLVLQSPGSNRSNLSSPQDSPQDSPRLKNLAEEISPPPTEQHQHQSPITDINLILENVDTIIHSNEQLPPPPSSTTPPPPPPPLTTTDSVIIEDYKSDGGNLNIENNNSNNTILTNAATSMNNSTSSLSSTSLPTTTTTTTAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPSQQQQQQQQQLSQQQQLQIKKKRSSISPSTSSNKLLLSGNGSGDSIRVVTDSGSSPRGQPRSMSSLHDHADSSYCQKSNIDLIDPTCSDFYFGVWIATAASNTRIYDTVFPAIPKNSIKTCEQFAQLQKIPVSLADSKLLSEVRGNLVFHPLDFLEGEDLQPSFLFTDDLFQ
What is the function of this protein?
Plays a role in cell growth.  Hydrolyzes membrane phospholipids, such as PtdCho free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own).  Involved in the inhibition of actin-based motility and endocytosis.  Its inhibition causes complete collapse of F-actin organization.
What are the official names of this protein?
Phospholipase D A, Phosphatase D1, PLD 1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
Protein: YL482_MIMIV
Sequence: YLTEISGKGHIEIVKCLVNLGANITTNNNYAIIQASEKGHLEVVKYLVGQNANIRSENNLAVRLASGNGHLEVVEYLVNLGADIRSENNYAIQSASQNGHLEVIEYLVA
What are the official names of this protein?
Putative ankyrin repeat protein L482.
Protein: PRMA_CITK8
Sequence: MPWIQLKLNTTGTNAEELSDALVETGAVSVTFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMKEVVAILEHHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSERLELYLPKDQPEAMKADVVVANILAGPLRELAPLISVLPVESGLLGLSGILASQAESVCEAYTELFTLDPVVEKEEWCRITGRKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNF_SHIBS
Sequence: MGLIWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFGLDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFSLKALLGVACIMSGLMLIFLPTTKQRY
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYGA_TOLAT
Sequence: MQKFDIKTFQGLILSLQDYWARQGCVISQPLDMEVGAGTSHPMTFLRSIGPEPMNCAYVQPSRRPTDGRYGENPNRLQHYYQFQVILKPSPDNIQELYLGSLRELGFDPLVHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECFPVTGEITYGLERLAMYIQGVDSLYDLVWADGPLGKVTYRDVFHQNEVEQSTYNFEHADVPFLFQLFDQCEKECQHLLNLELPLPLPAYERILKAAHAFNLLDARHAISVTERQRYILRIRTLSKAVAEAYYAARERLGFPMCKATQA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_THEFY
Sequence: MTRDRPTLLARVLILPIRGYQRWISPLFPPVCRFYPSCSSYAVEALRVHGAGRGLWLTIRRLGKCHPFHPGGLDPVPPRRNESGTEISDARPGSDGEASPGAPGL
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UCRI_PROM1
Sequence: MTQMTTADVPSMGRRQFMNLLTFGTVTGVALGALYPVAQYFTPYRAGGGGGGTNAKDELGNNVSASGWLSTHPVGDRSLVQGLKGDPTYLIVEGEDAITSYGINAICTHLGCVVPWNSGANKYMCPCHGSQYDSTGKVVRGPAPLSLAIAHVSIEDDQVLVSQWTETDFRTGTDPWWG
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, ISP, RISP, Rieske iron-sulfur protein.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: RL5_CLOBM
Sequence: MMPRLQEKYEKEVVSALMDKFGYKNIMEVPKLEKIVINMGVGEAKENQKALEAAVEDLAKITGQKPILTKAKKSVANFKIRENMPLGCKVTLRKQNMYEFADKLINVALPRVRDFSGVSSKSFDGRGNYAIGIKEQLIFPEIEFDKIDKIRGMDIIFVTTAKTDEEARELLRFLGMPFAR
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: EGT2_SCHPO
Sequence: MAENNVYGHEMKKHFMLDPDYVNVNNGSCGTESLAVYNKHVQLLKEAQSKPDFMCNAYMPMYMEATRNEVAKLIGADSSNIVFCNSATDGISTVLLTFPWEQNDEILMLNVAYPTCTYAADFAKNQHNLRLDVIDVGVEIDEDLFLKEVEQRFLQSKPRAFICDILSSMPVILFPWEKVVKLCKKYNIVSIIDGAHAIGHIPMNLANVDPDFLFTNAHKWLNSPAACTVLYVSAKNHNLIEALPLSYGYGLREKESIAVDTLTNRFVNSFKQDLPKFIAVGEAIKFRKSIGGEEKIQQYCHEIALKGAEIISKELGTSFIKPPYPVAMVNVEVPLRNIPSIETQKVFWPKYNTFLRFMEFKGKFYTRLSGAVYLEESDFYYIAKVIKDFCSL
What is the function of this protein?
Catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine by cleaving the cysteine residue at the sulfur atom, the last step in the biosynthesis pathway of ergothioneine.
What are the official names of this protein?
Hercynylcysteine sulfoxide lyase, Ergothioneine biosynthesis protein 2, PLP-binding cysteine desulfurase, PLP-dependent C-S lyase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.