PharMolix/UniProtQA huggingface dataset:
Protein: TRUB_HALS3
Sequence: MGIRPPPGERSPAAVLSFGVVNLDKPPGPSAHQVSAWIRDLVGVEKAAHAGTLDPKVTGCLPVLTGTATRIAPALLEGFKEYVAVLELHDDPPRILPDVIEAFTGEIYQKPPKKSAVARRLRTRTVYDLDVLDVDGRQVLLRIRCESGTYIRKLCHDIGRALGTNAHMGHLRRSATTPFDDTDLVTLHDLADAVAWLRDTDDTEPPDAPADALRAAVQPAERALTHLPRLTIADSAAHEVATGAPVYAPGVIDTTALPTPPADGALVACYTAGGTAVCLGRLVGDPDADAGVVVALERVLV
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: KKCC1_RAT
Sequence: MERSPAVCCQDPRAELVERVAAISVAHLEEAEEGPEPASNGVDPPPRARAASVIPGSASRPTPVRPSLSARKFSLQERPAGSCLEAQVGPYSTGPASHMSPRAWRRPTIESHHVAISDTEDCVQLNQYKLQSEIGKGAYGVVRLAYNEREDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAPQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFPEEQARLYLRDIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDTGQSFSGKALDVWATGVTLYCFVYGKCPFIDEYILALHRKIKNEAVVFPEEPEVSEELKDLILKMLDKNPETRIGVSDIKLHPWVTKHGEEPLPSEEEHCSVVEVTEEEVKNSVKLIPSWTTVILVKSMLRKRSFGNPFEPQARREERSMSAPGNLLLKEGCGEGGKSPELPGVQEDEAAS
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes.  Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4.  Involved in regulating cell apoptosis.  Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase kinase 1, CaM-KK 1, CaM-kinase kinase 1, CaMKK 1, CaM-kinase IV kinase, Calcium/calmodulin-dependent protein kinase kinase alpha, CaM-KK alpha, CaM-kinase kinase alpha, CaMKK alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL18_SOLUE
Sequence: MIRKIEKKEIRNRIHRRIRRKLSGTAERPRLAVFRSVAHIYAQVIDDAQGQTLVSASSVDKDGKSKGGNVAAAKAIGKLVAERAKEKGIKSVVFDRGGYQYHGRVKALADAAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MMPS2_MYCBO
Sequence: MISVSGAVKRMWLLLAIVVVAVVGGLGIYRLHSIFGVHEQPTVMVKPDFDVPLFNPKRVTYEVFGPAKTAKIAYLDPDARVHRLDSVSLPWSVTVETTLPAVSVNLMAQSNADVISCRIIVNGAVKDERSETSPRALTSCQVSSG
What are the official names of this protein?
Probable transport accessory protein MmpS2.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DNAA_CAMJJ
Sequence: MNPSQILENLKKELNENEYENYLSNLKFNEKQSKADLLVFNAPNELMAKFIQTKYGKKIAHFYEVQSGNKAIINIQAQSAKQSNKSTKIDIAHIKAQSTILNPSFTFDSFVVGDSNKYAYGACKAITHKDKLGKLYNPIFVYGPTGLGKTHLLQAVGNASLEMGKKVIYATSENFINDFTSNLKNGSLDKFHEKYRNCDVLLIDDVQFLGKTDKIQEEFFFIFNEIKNNDGQIIMTSDNPPNMLKGITERLKSRFAHGIIADITPPQLDTKIAIIRKKCEFNDINLSNDIINYIATSLGDNIREIEGIIISLNAYATILGQEITLELAKSVMKDHIKEKKENITIDDILSLVCKEFNIKPSDVKSNKKTQNIVTARRIVIYLARALTALTMPQLANYFEMKDHTAISHNVKKITEMIENDASLKAKIEELKNKILVKSQS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMPA_SYNE7
Sequence: MNEFQPVNRRQFLFTLGATAASAILLKGCGNPPSSSGGGTSSTTQPTAAGASDLEVKTIKLGYIPIFEAAPLIIGREKGFFAKYGLDVEVSKQASWAAARDNVILGSAGGGIDGGQWQMPMPALLTEGAISNGQKVPMYVLACLSTQGNGIAVSNQLKAQNLGLKLAPNRDFILNYPQTSGRKFKASYTFPNANQDFWIRYWFAAGGIDPDKDIELLTVPSAETLQNMRNGTIDCFSTGDPWPSRIAKDDIGYQAALTGQMWPYHPEEFLALRADWVDKHPKATLALLMGLMEAQQWCDQKANRAEMAKILSGRNFFNVPVSILQPILEGQIKVGADGKDLNNFDAGPLFWKSPRGSVSYPYKGLTLWFLVESIRWGFNKQVLPDIAAAQKLNDRVTREDLWQEAAKKLGVPAADIPTGSTRGTETFFDGITYNPDSPQAYLQSLKIKRA
What is the function of this protein?
Part of the ABC transporter complex CmpABCD involved in bicarbonate transport.  Binds bicarbonate with high affinity.
What are the official names of this protein?
Bicarbonate-binding protein CmpA.
What is the protein family that this protein belongs to?
Belongs to the CmpA/NrtA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DUS10_HUMAN
Sequence: MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLGSANPGSNSHPPVIATTVVSLKAANLTYMPSSSGSARSLNCGCSSASCCTVATYDKDNQAQTQAIAAGTTTTAIGTSTTCPANQMVNNNENTGSLSPSSGVGSPVSGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENTNEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVETVV
What is the function of this protein?
Protein phosphatase involved in the inactivation of MAP kinases.  Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily.  It preferably dephosphorylates p38.
What are the official names of this protein?
Dual specificity protein phosphatase 10, Mitogen-activated protein kinase phosphatase 5, MAP kinase phosphatase 5, MKP-5.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NXT1_HUMAN
Sequence: MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQASPSNTVWKIASDCFRFQDWAS
What is the function of this protein?
Stimulator of protein export for NES-containing proteins (PubMed:10567585).  Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA (PubMed:10848583).  The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 (PubMed:19165146, PubMed:11259602).
What are the official names of this protein?
NTF2-related export protein 1, Protein p15.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: SCN7A_HUMAN
Sequence: MLASPEPKGLVPFTKESFELIKQHIAKTHNEDHEEEDLKPTPDLEVGKKLPFIYGNLSQGMVSEPLEDVDPYYYKKKNTFIVLNKNRTIFRFNAASILCTLSPFNCIRRTTIKVLVHPFFQLFILISVLIDCVFMSLTNLPKWRPVLENTLLGIYTFEILVKLFARGVWAGSFSFLGDPWNWLDFSVTVFEVIIRYSPLDFIPTLQTARTLRILKIIPLNQGLKSLVGVLIHCLKQLIGVIILTLFFLSIFSLIGMGLFMGNLKHKCFRWPQENENETLHNRTGNPYYIRETENFYYLEGERYALLCGNRTDAGQCPEGYVCVKAGINPDQGFTNFDSFGWALFALFRLMAQDYPEVLYHQILYASGKVYMIFFVVVSFLFSFYMASLFLGILAMAYEEEKQRVGEISKKIEPKFQQTGKELQEGNETDEAKTIQIEMKKRSPISTDTSLDVLEDATLRHKEELEKSKKICPLYWYKFAKTFLIWNCSPCWLKLKEFVHRIIMAPFTDLFLIICIILNVCFLTLEHYPMSKQTNTLLNIGNLVFIGIFTAEMIFKIIAMHPYGYFQVGWNIFDSMIVFHGLIELCLANVAGMALLRLFRMLRIFKLGKYWPTFQILMWSLSNSWVALKDLVLLLFTFIFFSAAFGMKLFGKNYEEFVCHIDKDCQLPRWHMHDFFHSFLNVFRILCGEWVETLWDCMEVAGQSWCIPFYLMVILIGNLLVLYLFLALVSSFSSCKDVTAEENNEAKNLQLAVARIKKGINYVLLKILCKTQNVPKDTMDHVNEVYVKEDISDHTLSELSNTQDFLKDKEKSSGTEKNATENESQSLIPSPSVSETVPIASGESDIENLDNKEIQSKSGDGGSKEKIKQSSSSECSTVDIAISEEEEMFYGGERSKHLKNGCRRGSSLGQISGASKKGKIWQNIRKTCCKIVENNWFKCFIGLVTLLSTGTLAFEDIYMDQRKTIKILLEYADMIFTYIFILEMLLKWMAYGFKAYFSNGWYRLDFVVVIVFCLSLIGKTREELKPLISMKFLRPLRVLSQFERMKVVVRALIKTTLPTLNVFLVCLMIWLIFSIMGVDLFAGRFYECIDPTSGERFPSSEVMNKSRCESLLFNESMLWENAKMNFDNVGNGFLSLLQVATFNGWITIMNSAIDSVAVNIQPHFEVNIYMYCYFINFIIFGVFLPLSMLITVIIDNFNKHKIKLGGSNIFITVKQRKQYRRLKKLMYEDSQRPVPRPLNKLQGFIFDVVTSQAFNVIVMVLICFQAIAMMIDTDVQSLQMSIALYWINSIFVMLYTMECILKLIAFRCFYFTIAWNIFDFMVVIFSITGLCLPMTVGSYLVPPSLVQLILLSRIIHMLRLGKGPKVFHNLMLPLMLSLPALLNIILLIFLVMFIYAVFGMYNFAYVKKEAGINDVSNFETFGNSMLCLFQVAIFAGWDGMLDAIFNSKWSDCDPDKINPGTQVRGDCGNPSVGIFYFVSYILISWLIIVNMYIVVVMEFLNIASKKKNKTLSEDDFRKFFQVWKRFDPDRTQYIDSSKLSDFAAALDPPLFMAKPNKGQLIALDLPMAVGDRIHCLDILLAFTKRVMGQDVRMEKVVSEIESGFLLANPFKITCEPITTTLKRKQEAVSATIIQRAYKNYRLRRNDKNTSDIHMIDGDRDVHATKEGAYFDKAKEKSPIQSQI
What is the function of this protein?
Mediates the voltage-dependent sodium ion permeability of excitable membranes.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
What are the official names of this protein?
Sodium channel protein type 7 subunit alpha, Putative voltage-gated sodium channel subunit alpha Nax, Sodium channel protein cardiac and skeletal muscle subunit alpha, Sodium channel protein type VII subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. SCN7A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WRK43_ARATH
Sequence: MNGLVDSSRDKKMKNPRFSFRTKSDADILDDGYRWRKYGQKSVKNSLYPRSYYRCTQHMCNVKKQVQRLSKETSIVETTYEGIHNHPCEELMQTLTPLLHQLQFLSKFT
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
What are the official names of this protein?
Probable WRKY transcription factor 43, WRKY DNA-binding protein 43.
What is the protein family that this protein belongs to?
Belongs to the WRKY group II-c family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THEG_MOUSE
Sequence: MGELGEHRASLLSNPIPEVKTLGELKQGQNNGNLDLESEPFGSHWLQGSKATTGRTSEEPEEEIPPEEMAGEELPETSNLDGPLQQDLEVEVVEMSHLSITERTPSVSTAKGRKKRSRRLLELAKPKTNWQCLRDRTGRCCKGYAWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPVVSQRMEELSRPKRFYQEYYNNNRTTPIWSIPRSTLEYQASNRLKQLATPKVRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRPPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLDVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELATPKYITKKV
What is the function of this protein?
May be involved (but not essential) in spermatogenesis.
What are the official names of this protein?
Testicular haploid expressed gene protein.
Protein: FOXA3_HUMAN
Sequence: MLGSVKMEAHDLAEWSYYPEAGEVYSPVTPVPTMAPLNSYMTLNPLSSPYPPGGLPASPLPSGPLAPPAPAAPLGPTFPGLGVSGGSSSSGYGAPGPGLVHGKEMPKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATTTRNGTGSAASTTTPAATVTSPPQPPPPAPEPEAQGGEDVGALDCGSPASSTPYFTGLELPGELKLDAPYNFNHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGVYYQGLYSRSLLNAS
What is the function of this protein?
Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity).  Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc.  Interacts with the cis-acting regulatory regions of these genes.  Involved in glucose homeostasis; binds to and activates transcription from the G6PC1 promoter.  Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA.  Binds to the CYP3A7 promoter together with members of the CTF/NF-I family.  Involved in regulation of neuronal-specific transcription.  May be involved in regulation of spermatogenesis.
What are the official names of this protein?
Hepatocyte nuclear factor 3-gamma, HNF-3-gamma, HNF-3G, Fork head-related protein FKH H3, Forkhead box protein A3, Transcription factor 3G, TCF-3G.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPPP_NEIMA
Sequence: MDFLIVLKALMMGLVEGFTEFLPISSTGHLIVFGNLIDFHSNHKVFEITIQLGAVLAVVFEYRQRFSNVLHGVGKDRKANRFVLNLAIAFIPAAVMGLLFGKQIKEYLFNPLSVAVMLVLGGFFILWVEKRQSRAEPKIVDVDALRPIDALMIGVAQVFALVPGTSRSGSTIMGGMLWGIERKTATEFSFFLAVPMMVAATAYDVLKHYRFFTLHDVGLILIGFVAAFVSGLVAVKALLRFVSKKNYIPFAYYRIVFGIAIIILWLSGWISWE
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CA174_BOVIN
Sequence: MRSRKLAGGVRSSARLRARSCSAASASAQDTHVTTSAQTACQTPSSHKATDRRTSKKFKYDKGHIVKSELQKHRSDSAATPSETPGTHEPLASAEDGASLLGKEAGGSTPQGTAGPLPGRCGTESDASPAETENEPLPPRHGAPVGGESNGGCPARDGAALDLEQGPGAPLLMDGSALLDDDSNQPMPVSRFFGNVELMQDLPPVSSSCPSMSRREFRKMHFRAKDDEEDDADGAET
What are the official names of this protein?
UPF0688 protein C1orf174 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0688 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLE5_ARATH
Sequence: MATLILKQTLIILLIIFSLQTLSSQARILRSYRAVSMGNMDSQVLLHELGFDLSKFKGHNERRFLVSSDRVSPGGPDPQHH
What is the function of this protein?
Extracellular signal peptide that regulates cell fate.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 5.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
[CLE5p]: Secreted, extracellular space.
Protein: LTC4S_HUMAN
Sequence: MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA
What is the function of this protein?
Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4 with high specificity (PubMed:7937884, PubMed:27791009, PubMed:27365393, PubMed:9153254, PubMed:23409838).  Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions (PubMed:27791009).
What are the official names of this protein?
Leukotriene C4 synthase, LTC4 synthase, Glutathione S-transferase LTC4, Leukotriene-C(4) synthase, Leukotriene-C4 synthase.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Nucleus outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Protein: PLSX_BRUA2
Sequence: MIKISIDAMGGDFGPEVVIPGAAKAFERHPDIRFIFFGLPAQVEPVLARYPKLKEASEFRASEVAIGMDDKPSQALRAGRGKSSMWQAIEAVKTGDADACVSAGNTGALMAMSKFCLRMMSDVERPAIAGIWPTLRGESIVLDIGATIGADARQLVDYAVMGAGMARALFEVRKPTVGLLNVGTEEVKGLDEIKEAGQILRDTPLDGLEYSGFVEGNDIGKGTVDVVVTEGFTGNIALKTAEGTARQMAELLRQAMSRTLLAKIGYVFAKGAFDRLREKMDPNKVNGGVFLGLSGIVIKSHGGANAEGFCSAVEVGYDMVRNRLLEKIEADLAHFHHSHSHVSSKA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: FABPH_ICTTR
Sequence: MVDAFVGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDTIILKTQSTFKNTEISFQLGKEFDETTADDRKVKSTVTLDGGKLVHVQKWDGQETTLVRELNDGKLILTLTHGSVVCTRTYEKEA
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.  FABPs are important elements related to the hibernating state in mammals.
What are the official names of this protein?
Fatty acid-binding protein, heart, Fatty acid-binding protein 3, Heart-type fatty acid-binding protein, H-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAB_ECOSE
Sequence: MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFKNGLHSQNGYVTWNVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLMPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINPNDDRFINPEAMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGEDFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: DPO4_COLP3
Sequence: MGNQKKIIHIDMDCFYAAIEMRDFPEYQNIPLAVGGDGPRSVLCTSNYQARQFGVRSAMPAIKAKQLCPHLKIVHGRMDVYKETSKNIREIFSRYTDLIEPLSLDEAYLDVTDATMCQGSATLIAERIRADIFNELNLTASAGIAPNKFLAKIASDENKPNGQCVITPDKVANFVEQLSLKKIPGIGPKTFEKLNRHGYVTCADVRQSNIRALQNIVGKFANSLYLKSHGVDNRDLEVSRQRKSLAIETTLAHDISTQDECKLVIDSLYQKLLTRLAPHSNREIIRQGVKLKFTDFNQTTVETQSNECQQALFISLLSKAYSRSNKRGVRLVGLTLGFADSPGESQQLSLSL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELU_SALDC
Sequence: MQDRQKAQDYRAILLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: NUOCD_SHEWM
Sequence: MSIFTQEVSAINGQSGNIKQMLTLEMLPELKSLLSDSVEQQICIDGILTLWIDKTQLIPALRLLKTLPQPFDLLLDLFGVDERLRLDKDKLPAQDFTLVYQLCSINRNQDIRLKVALANDQAEIPSITAFWPSANWYEREAWDMFGIIFSDHPNLYRLLLPPTFKGHPLRKEFPCRATETEAFSLDDERLAIEQEALKFDPKRWGMEQSNKDNDYLFLNLGPNHPSVHGVFRIALQLDGEHIINSVPDIGYHHRGAEKIAERQTWHGFIPYTDRIDYLGGVMNNFPYILAIEQLANIQVSERVKCIRVMLAECFRILSHMLFFGTFAQDVGQLSPIFYLFIDREKLFGIIEAITGARMHPSWFRIGGLAQDLPKGWDTMMQEFVDEFPKKLDEYEVMVMQNSILKRRSIGIGQYNTQEALDWNITGAGLRATGLEWDLRKARPYSGYENYDFEVPTGHKGDAYDRCQLRVEEMRQSVKIIQQCINNMPEGEVKADHPLTTPPSQRSKHDIETLIQHFLNVSWGPVMPKGESCFAVEATKGVNAYTIISDGSNTSYRTRIRTPSFAHLQMIPKMAKGLMVADLIVILASIDFVMADVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GP6D_CHLPS
Sequence: MSKLTKEASAFFQKNQENTTKEFLKKEFAMDVFSVSLSDIEKEQIENLVVSQNSKFDEEYNRGLASIKLLTGQIKSIQKQHVLLIGEKIYKVREILKNMNSPDTTFSSWINLVFRTKSSAYNALGYYELFISLPDKNTKSLFQSIPYKTAYLLASRKGSVKDKLKVLGKISGLSNALAIDVLNKFLPPLKSSQTERCVDFEEKNKEVSEKLIDILKIVSSGLELSEYNKNLLHQLFEKTLKVDIRC
What are the official names of this protein?
Virulence plasmid protein pGP6-D.
What is the protein family that this protein belongs to?
Belongs to the UPF0137 (pGP6-D) family.
Protein: RBSU_LACPL
Sequence: MNTTALLIGLGPLLGWGLYPTIASKIGGRPVNQILGSTIGTLIFALIYAWVQGIAFPSGMNLWFSILSGIGWASAQIVTFKVFTMVGSSRAMPITTAFQLLGASLWGVFALGDWPGAMDKVLGGLALVGIIIGAWLTVWSEHKDAGNARTLRQAVIWLAVGEIGYWAYSAAPQATNIGGEEAFVPQAIGMVIVSIVYALFLASRGEKLALVEGVSYTHIISGFFFAFAALTYLISAQPNMNGLATGFILSQTSVVLATLTGIWFLGQKKTTKEMWVTIGGLILIIAAAAVTVTI
What is the function of this protein?
Could be involved in the uptake of ribose.
What are the official names of this protein?
Putative ribose uptake protein RbsU.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAA_NEIG2
Sequence: MPTPKAFTLLGPTACGKTALALKIAETLPVEIISLDSALLYTGMDIGTAKPSASERAFVPHHLIDIITPVQTYSAARFVEDCTRLTGEITARGKCPLIVGGTMMYFRALTQGLNDLPEADACLRADLDEQKQMYGLDFLYRTLQKVDPETACRLKPNDSQRIGRALEVYYLTGRPMSAHLNGQPEHTLPFELYTAALIPENRARLHENIALRFHLMLEQGFIGEVENLRRRYPGLTADSPAIRCVGYRQAWEHLDGATDRQTFIEKGIAATRQLAKRQLTWLRKTPLDCVADPFSDGTSGTRLIEAAKRFFGE
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TTCA_METPP
Sequence: MSAVVIEPGVTQRQAGKPAFEANKLSKRLHRLVGQAIGDFNMIEPGDKLMVCVSGGKDSYALLDILLNLQQRAPIDFSLVAVNLDQKQPDFPEHVLPEYLASRGVPFHIENQDTYSIVKRVVPEGKTMCSLCSRLRRGILYRVAGELGATKIALGHHRDDMLQTLFLNMFFGAKLKGMPPKLVSDDGRHVVIRPLAYVPEHDLEAWAAHRQFPIIPCTLCGSQENLQRKQIAQMLRDWERQHPGRLDNMASALANVVPSHLQDRNLYPFTTLQATGRADELGDKAFDDDETCAPPGAASVIEAAMPIRWHGQG
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.