PharMolix/UniProtQA huggingface dataset:
Protein: SKI2_SCHPO
Sequence: MSSKLVDAINEVAVSNKDKIELDGIKDDSFDGHLSITEATYDVDTFLKPSPALSKDWIRKLQKKWDREITYKGLYEYPETLARTQIRFQRHGLEGKIMGYKEVPELIEDLNSKNSSSFLRKPSSKNEFVRGSTSNIPFLADDSDVDAIAGEPSVKMALYGEDGLLQVPPGFSRGLSMTATSTTDNLNDEFDPEKWDTKKVKSSNRNFVTIHELNEHLKNVNSKHSEIDDLLPDKRSIVSLPPSTLNLHKQPDYAHVVDSSAPIENFQQLVPEMALDFPFELDNFQKEAIYHLEMGDSVFVAAHTSAGKTVVAEYAIALAQKHMTKAIYTSPIKALSNQKFRDFKHKFEDVGILTGDVQVNPEGSCLLMTTEILRSMLYRGADLIRDVEFVIFDEVHYVNDLERGVVWEEVIIMLPPHVTLILLSATVPNTKEFASWVGRTKKKNIYVISTLKRPVPLEHYLWVKQNMFKIVDQHGRFLMDGYKSANDALKKPDKPVIAKDNKNSARGRGAARGRGVQTNMMRGRGSAKSVERRDANTWVHLIGHLHKQNLLPVIVFVFSKKRCEEYVDTLTNRDLNNHQEKSEVHVVIEKAVARLKKEDRLLPQIGRMREMLSRGLAVHHGGLLPIIKEIVEILFQRGLVKVLFATETFAMGVNMPAKSVVFSGTQKHDGRNFRDLLPGEYTQCSGRAGRRGLDVTGTVIILSRSELPDTASLRHMIMGPSSKLISQFRLTYNMILNLLRVETLRIEDMIKRSFSENVNQTLVPQHEEKIKSFEEKLSALKKEMSDVDLKEIKSCLLSSESFKEYTKKMHFRAITTANGKRIFKDGRVIVFQQLDFTRTVGVLLGTSIRTNASDCTLEVAYLNPQNNLKRPSDLLAFADAFNDVYDNAIFDESNQFKYGLINLSGIERVCNTILRIDSGGIRDRRGGAFRKLSEQFASIKKFSDLLFEEVNWSKVRDFEFCEAFEKRNFLQNKLSGNPIISTPNFLTHFALAYQEYELESNIDNLSSYISDQNLELLPDYEQRIKVLQELGYIDAERTVLLKGRVACEINSTSELVLTELILENSLADFSCEETIALLSAFVFDEKTEVEPTISPHLQKGKEMILSVAEKVNQIQEHYQVLYFNEGNDFESQPRFGLMEVCYEWARGMSFNRITDLTDVLEGSIVRTIIRLDEVLRECRGAARVVGDSSMYTKMEECQNLIRRNIVFCPSLYM
What is the function of this protein?
RNA helicase component of the SKI complex involved in 3'-mRNA degradation pathway.
What are the official names of this protein?
Putative ATP-dependent RNA helicase C550.03c.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_VIBPA
Sequence: MATIKVTQTKSSIGRLPKHKATLRGLGLRKINHTVELEDTPCVRGMINKVYYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RBFA_LEPCP
Sequence: MRNKRVIPNRTFRVSDQIQRDVAELIRDLKDPRIGMVTINSVDITPDYAHAKVYFSVLIGDAADSELALNEAAGFLRNGLFKRLQIHTVPTLHFHFDRTTERAAELSALITQANARRALDSDQ
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVK_METTH
Sequence: MKSSASAPAKAILFGEHAVVYSKPAIAAAIDRRVTVTVSESSSTHVTIPSLGIRHSSERPSGGILDYIGRCLELYHDASPLDIRVEMEIPAGSGLGSSAALTVALIGALDRYHGRDHGPGETAARAHRVEVDVQGAASPLDTAISTYGGLVYLDSQRRVRQFEADLGDLVIAHLDYSGETARMVAGVAERFRRFPDIMGRIMDTVESITNTAYRELLRNNTEPLGELMNLNQGLLDSMGVSTRELSMMVYEARNAGAAGSKITGAGGGGSIIAHCPGCVDDVVTALNRNWKAMRAEFSVKGLI
What is the function of this protein?
Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP).  Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
What are the official names of this protein?
Mevalonate kinase, MK, MVK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE2_RICAH
Sequence: MTNVITRFAPSPTGFLHIGSARTALFNYLFARHNNGKFLLRIEDTDKERSTKAAVDAIFSGLKWLGLDWDAEVIFQSKRNDLYKKAALRLLKEGKAYYCFTSQEEIEKQRQKALENKQHFIFNSEWRDKEPDAYPTDVKPVIRLKTPREGRITIHDTLQGEVVIENSHIDDMVLLRADGTATYMLAVVADDHDMGITHIIRGDDHLTNAARQIAIYQALGYEVPSMTHIPLIHGADGAKLSKRHGALGVDAYKNMGYLPESLCNYLLRLGWSHGNDEIISMTQAIEWFNLDSLGKSPSRLDFAKMNSLNAYYLRMLDNDTLTAKTVEILKQNYKISDKEVSYIKQAMSSLLVRSETLLDLAQLAQIYLVDSPIVYNQDAKEIIENCNKDLIKQVTEGLNKIEKFDKESVQNKFKEIAAANDLKLSDIMKPVRALITGMDASPSVFAIAEILGKENILKRLETI
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCAM_MOUSE
Sequence: KTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGLDLDDVCAEAQDGELDGLWTTITIFISLFLLSVCYSASVTLFKVKWIFSSVVELKQTISPDYRNMIGQGA
What are the official names of this protein?
Ig gamma-2A chain C region, membrane-bound form.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: 3L243_DRYCN
Sequence: MKTLLLTLVVVTIVCLDLAYTRKCYKTHPYKSEPCAPGENLCYTKTWCDFRCSQLGKAVELGCAATCPTTKPYEEVTCCSTDDCNRFPNWERPRPRPRGLLSSIMDHP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 43, LNTX-43.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYTA_SARPE
Sequence: MKYVLILCVITLATVAYAQPQCVGCPSEVKGDKLKQSEETLNKSLSKLAAGDGPTYKLVKINSATTQVVSGSKDVINADLKDENDKTKTCDITIWSQPWLENGIEVTFNCPGEPKVVKKHSA
What is the function of this protein?
Selectively inhibits the activity of cysteine proteinase of hemocytes, protecting developing adult tissue in pupae from attack by the proteinase.
What are the official names of this protein?
Sarcocystatin-A.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
Protein: RINO1_ORYSJ
Sequence: MFIESFRVESPHVRYGAAEIESDYQYDTTELVHESHDGASRWIVRPKSVRYNFRTTTTVPKLGVMLVGWGGNNGSTLTAGVIANREGISWATKDKVQQANYYGSLTQASTIRVGSYNGEEIYAPFKSLLPMVNPDDLVFGGWDISNMNLADAMTRAKVLDIDLQKQLRPYMESMVPLPGIYDPDFIAANQGSRANNVIKGTKKEQMEQIIKDIREFKEKSKVDKVVVLWTANTERYSNVCVGLNDTMENLLASVDKNEAEISPSTLYAIACVMEGIPFINGSPQNTFVPGLIDLAIKNNCLIGGDDFKSGQTKMKSVLVDFLVGAGIKPTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVSSNAILYELGEHPDHVVVIKYVPYVGDSKRAMDEYTSEIFMGGKSTIVLHNTCEDSLLAAPIILDLVLLAELSTRIQLKAEGEEKFHSFHPVATILSYLTKAPLVPPGTPVVNALAKQRAMLENIMRACVGLAPENNMILEYK
What is the function of this protein?
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner (By similarity).  Is a key enzyme in the phytic acid biosynthesis pathway in seeds (PubMed:19021878).
What are the official names of this protein?
Inositol-3-phosphate synthase 1, MIP synthase 1, Myo-inositol 1-phosphate synthase, IPS, MI-1-P synthase, OsINO1-1.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIZFM_STRCO
Sequence: MTVESVNPETRAPAAPGAPELREPPVAGGGVPLLGHGWRLARDPLAFMSQLRDHGDVVRIKLGPKTVYAVTNPELTGALALNPDYHIAGPLWESLEGLLGKEGVATANGPLHRRQRRTIQPAFRLDAIPAYGPIMEEEAHALTERWQPGKTVDATSESFRVAVRVAARCLLRGQYMDERAERLCVALATVFRGMYRRMVVPLGPLYRLPLPANRRFNDALADLHLLVDEIIAERRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVVAILTPGSETIASTIMWLLQALADHPEHADRIRDEVEAVTGGRPVAFEDVRKLRHTGNVIVEAMRLRPAVWVLTRRAVAESELGGYRIPAGADIIYSPYAIQRDPKSYDDNLEFDPDRWLPERAANVPKYAMKPFSAGKRKCPSDHFSMAQLTLITAALATKYRFEQVAGSNDAVRVGITLRPHDLLVRPVAR
What is the function of this protein?
Involved in the biosynthesis of the sesquiterpenoid antibiotic albaflavenone.  Catalyzes the two-step allylic oxidation of epi-isozizaene to albaflavenone.  First carries out a non-stereo-specific oxidation of epi-isozizaene to give a mixture of the albaflavenol epimers ((5R)-albaflavenol and (5S)-albaflavenol), each of which can serve as substrate for the second oxidation to yield albaflavenone.  This is quite different from most other P450s which catalyze regio- and stereospecific oxidation (PubMed:18234666, PubMed:19858213).  In addition, displays a farnesene synthase activity with farnesyl diphosphate (FPP) as substrate (PubMed:19858213).
What are the official names of this protein?
Bifunctional albaflavenone monooxygenase/terpene synthase, Cytochrome P450 170A1, CYP170A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: HYBA2_BIFL2
Sequence: MHHSTRKRWLASIGAVAAVATLATGGAVTAQAADAPVIKNADVAYPSFKGSDDPMKTAANNTTYNPAVSYLQETFDNDVKNLAGIDTDHDFWIDKILTRTGAQPTGKGTNDKGAYSYEGSDGNNYLFTRGRAAYMYTHTPNQLGFVGDTAYWDQTSRSGFTVTVNADGSNQTLNEDASQRKQTPSYFTSLFQTGGKSLKIKEVKYITYNNVMVANLTVESTQDRDVTLTTASPFAAEGADGATELTGRVNVKNNLTTIYPRFSANNQDGSNWIVSGGKLTSTLSLKANEPQTVKIQLGLIANELPDSTKEYEARYTGDLKDAAASYKDSVTTYNKWWVDNAPYVDTPEDNIDKTVVYRWWLSRFNMLDANMPGNTFQYPTSIEGVLGYNNQIVLTSGMFMMDTKWFRNPEYSYGTWLSAGDTAKKSKAGYYYYHDNPGDPANWNHSYTQYITRAGWDSYKVHGGPSTVAEELADQGAEDVQGLLASKSEPDNNDNQNNNDNSLIDWSWWSMTGNDADAVSFSEPGRSGQRMDRADGSANMWANANAAAQAYKAAGDTANAEKMQAIADKIQKEVTTELWDKSDNLLKHKWLNDGAFAKYKEINNYYPYSEGLMPTGNEDYNKALRLFEDSNEFPIFPFFTANQADKAALNFPGSNNFSIINAQPLLQVYSAGIRNYDAAKNGYITNEQFKKLLYWVAFAHYQGGDNNYPDQNEFWNEDNNNVGDVNGDGVINNLDKNLDAAQNGGKITYRSWIHHTQLGTTNWTMVEDVAGMVPREDNKIELNPIEIPGWNYFTVNNLRYHDQDVSIVWDKDGSHYGGPAGYSLYVGGKLAFTSDKLAHLIYDPAAGTVEVKDDSSAQVTVGAEAVKNVKAANQVTFNADQRVTDLFAKSGTNVDSASKSTTNVAKDADVTGTTYAEKDTNYPAKNAVDGKTVMESFWGTKGSENKTDTLNIKFKDGKQKIDDIRLYFYQSSSSQTISGYAEPANYKLEYQKDDGTWAPIADQVRTPNYAGANYNRIQFTPVETTTIRVTFTPQAGMAVGVKEIEAYNTGIKADGTSENQTPQVDAYVSSSTSSGAKLVGTVKDDGLPAEGDVTTTWSQVSGPEGGTAKFVDASAASTTVTFNKEGDYVLKLTASDGEKEGSKEITVHGIPSDGTVNVAPQSSASASYTNGYQPKDNAKKVIDGQVVYANTPNETWNNWGDSTGVEPWLQLKWAGKVPLKKAKVFFWTDGGGVPMVSSWKLQYADADGNWQDVKLADGQSYTVNRNEGNEVKFADAVETDKLRVVFPKGAIVGASEFEAYAIEPVSVDEVNRLVQTGSKADDLKLPSTVSAVYTDGSRRDLAVTWGKVTDAQLAADAVFDVKGTVAGALNGTVAHIAARSDTASQTVGNAQPVEQTVYQNAKSIDLPATVPVKFPNGYNDDRKVTWKDADIKAIDLTKVGDYEVAGTVDDGSSSAAAKLTVHVVADPNGSSTPEPEPEPLVGWIEGKATRTTISPDSEATWSPAEGKLNDGVVVDDTWPTTDDQNVNDKVWGSWGKAKDGMYAQYDFGQSVTIDQSRAQFWANFAETDDSKGGLEVPDAWKIQYLAEDGSWKDVEPTEDYTVVRNSPASRADTDAKGWSAVTFKPVTTKSLRLVLTPYTGSSTFGAAVAEWGVHGIDGTEPEPTPVDKTALESALDTANGLDASRYTAASWAEFQQIIDAAQAVYDDANATAEQVAEQVTKLEDGQKALVALATDVEKSTLQAAIDAAKAEAASGKYTDKSVEALNKAIEAAEGVLKVGEVGEVTQAAVQEASASLNKAVKALEEKPAAETVKKESLEASIEQAKKADKSKYTEEAWQALQSQIAAAQKVYDDKDAKQADVDAAQDALDKAFWATKVEQKPGSQQPGVTDTDKDDKDNKGDRVPPTGAAVSVVAAAAVLLTAAGVTILKRRQSGDHGSARHSA
What is the function of this protein?
Beta-L-arabinobiosidase that removes L-arabinofuranose-beta-1,2-L-arabinofuranose disaccharide from various substrates such as carrot extensin and potato lectin.  Also acts on L-arabinofuranose (Ara)-beta-1,2-Ara-beta-1,2-Ara-beta-Hyp (Ara(3)-Hyp) but not on Ara-beta-1,3-Ara-beta-1,2-Ara-beta-1,2-Ara-beta--Hyp (Ara(4)-Hyp) or Ara-beta-1,2-Ara-beta-Hyp (Ara(2)-Hyp), suggesting a specificity for unmodified Ara(3)-Hyp substrate.  In the presence of 1-alkanols, shows transglycosylation activity, retaining the anomeric configuration of the arabinofuranose residue.
What are the official names of this protein?
Beta-L-arabinobiosidase, Arabinofuranosyl(3)-Hyp beta-L-arabinobiosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 121 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CYB_MYOHA
Sequence: MTNIRKSHPLMKIINNSFIDLPAPSNISSWWNFGSLLGICLTLQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYLYTETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFLLPFIISAMVMVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGLLLMIVVLLVLVLFSPDMLGDPDNYMPANPXNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIIPLLHTSKQRSMAFRPLSQCLFWLLVADLLTLTWIGGQPVEHPYVIIGQLASILYFCIIIILMPLAGLVENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SPR2A_HUMAN
Sequence: MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCPQPCPPQQCQQKYPPVTPSPPCQSKYPPKSK
What is the function of this protein?
Gut bactericidal protein that selectively kills Gram-positive bacteria by binding to negatively charged lipids on bacterial membranes, leading to bacterial membrane permeabilization and disruption (PubMed:34735226).  Specifically binds lipids bearing negatively charged headgroups, such as phosphatidic acid, phosphatidylserine (PS), cardiolipin (CL), and phosphatidylinositol phosphates, but not to zwitterionic or neutral lipids (PubMed:34735226).  Induced by type-2 cytokines in response to helminth infection and is required to protect against helminth-induced bacterial invasion of intestinal tissue (By similarity).  May also be involved in the development of the cornified envelope of squamous epithelia; however, additional evidences are required to confirm this result in vivo (PubMed:8325635).
What are the official names of this protein?
Small proline-rich protein 2A, SPR-2A, 2-1.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Cytoplasmic vesicle, secretory vesicle. Note=Present in intestinal secretory epithelial cells and is secreted into the intestinal lumen.
Protein: SYE_BURM1
Sequence: MTRPVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSSKEAVDAILEGMEWLGLDFDEGPIYQMQRMDRYREVLAQMLEKGLAYPCYMSAEELDALRERQRAAGLKPRYDGTWRPEPGKVLPEPPPGVKPVLRFRNPLTGTVAWDDAVKGRVEISNEELDDLVIARPDGTPIYNFCVVVDDMDMGITHVIRGDDHVNNTPRQINILRALGGEPPVYAHLPTVLNEQGEKMSKRHGAMSVMAYRDAGYLPEAVVNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKSPAQYDHNKLNWLNAHYIKEADNARLAALAKPFLAALAIDDAALAAGPALEAVIALMKDRATTVKEIAEGAAMFYRVPAPDADALAQHVSDAVRPALADLAAALKAADWTKEAISAALKATLAAHKLKMPQLAMPVRLLVAGTTHTPSIDAVLALFDRDVVVSRIEAALA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH42_BURL3
Sequence: MNQMNPAFVMPDVQSTVDTRQIPIQRVGVKAVRHPLTVCTESGDVQPTVGVWNLDVRLPADQKGTHMSRFVALLEENRAPLTVERFRAMLASMLEKLEAEAGRIEVTFPYFVNKTAPVSGVQSLLDYEVTLAGESRNGDTRLFLKVLVPVTSLCPCSKKISQYGAHNQRSHVTIDAELAADLPVEALIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVAQRLDADERVAAYVLEAENFESIHNHSAYALIERDKRQAA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2 2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: F229B_MACFA
Sequence: MPFRFGTQPRRFPVEGGDSSIGLEPGLSSSAACNGKEMSPTRQLRRCPGSHCLTITDVPITVYATMRKPPAQSSKEMHPK
What are the official names of this protein?
Protein FAM229B.
What is the protein family that this protein belongs to?
Belongs to the FAM229 family.
Protein: RECA_PHYMT
Sequence: MENNKKENNKKENNLKILEETIKEVEKQFGKGSIFKLNSNNNQSIETISTGSMSLDIALGIGGYPKGRIIEIFGPESSGKTTLTLHAIAEAQKLGGNVAFIDAEHALDPKYAQAIGVNIDELVLSQPDSGEKALDIATSLIKSGSISLLVIDSVAALTPESELMGEMKDINVGLQARMMGKAMRIQSGIISKTNTVVIYINQLREKVGNFYGNPEVTTGGKALKFFCSLRLDIRRTAEKIKNNNDEIIGVKSNIKIVKSKVSTPFKTATVDIIYGKGISKIGEILDLAIDLNLIKRNGAWYNYKNENFAQGKENAKIFLQNNLEIYNFLEEQIRKKYKI
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_PECAS
Sequence: MWIGVISLFPEMFRAITDFGVTGRAVKNGLLNVQYWSPRDFTYDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGARVIYLSPQGRKLDQQGVRQLATNQKMILVCGRYEGIDERVIKTEIDEEWSIGDYVLSGGELPAMTLIDSVARFIPGVLGHQASAEEDSFADGLLDCPHFTRPEILESMDVPAVLLSGNHAEIRRWRLKQSLGRTWLRRPELLKSLALTDEQTRLLAEFQREYQSEQQEY
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAUL_METEA
Sequence: MVMQTMLRVLTVSLAFALTSYALPAAADEFEVTIHHVELQDPGLKAKVGDAISFVNHADISHNLYLTYEDGQVETLDTQPPRTTKRTVLKRAGHVVVRCWIHPIIRMEFDVAAK
What is the function of this protein?
Probably involved in TTQ prosthetic group biosynthesis.
What are the official names of this protein?
Methylamine utilization protein MauL.
Protein: HEXI2_HUMAN
Sequence: MMATPNQTACNAESPVALEEAKTSGAPGSPQTPPERHDSGGSLPLTPRMESHSEDEDLAGAVGGLGWNSRSPRTQSPGGCSAEAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGCRCDEEPGT
What is the function of this protein?
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor (PubMed:15713661, PubMed:15713662).  Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (PubMed:15713661, PubMed:15713662).
What are the official names of this protein?
Protein HEXIM2, Hexamethylene bis-acetamide-inducible protein 2.
What is the protein family that this protein belongs to?
Belongs to the HEXIM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CS12B_ALIAG
Sequence: MAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEPGWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRGARDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVDLGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLEELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHADLNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGKKRRKVFAQEKLSEEEAELLVEADEAREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRSRVPLQDSACENTGDI
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein (By similarity).  The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA (By similarity).  Protein-crRNA-tracrRNA endonucleolytically cleave dsDNA target complementary to the spacer; protein is inactive in the absence of crRNA homologous to the target and tracrRNA (PubMed:26593719).  Recognizes a short motif in the CRISPR repeat sequences (the 5' PAM or protospacer adjacent motif, TTN in this organism) to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs (PubMed:26593719).  PAM recognition is also required for catalytic activity.  Cleavage results in staggered 6-8 base 5'-overhangs 14-17 and 23-24 bases downstream of the PAM (protospacer adjacent motif) on the non-target and target strands respectively (PubMed:27984729, PubMed:27989439).  Both target and non-target strand DNA are probably independently cleaved in the same active site (PubMed:27984729).
What are the official names of this protein?
CRISPR-associated endonuclease Cas12b, AacC2c1, CRISPR-associated endonuclease C2c1.
Protein: FBPAP_METTM
Sequence: MKTTISVIKADVGSVAGHAVAHEALKKKCDEILAEARDTGILEDYYITNCGDDIDLIMTHRNGEENEEVHQTAWNAFREATEVARGLKLYGAGQDLLSDTFSGNIKGMGPGCAEMEFKERPSDPVIIFCCDKTEPGAFNLPLFRMFADPFNTAGLVIDPTLHNGYEFEVFDVVEHKKVTMACPDEMYDLLALLGSISRYVIKKIHRRDDGEIAASVSTERLNLMAGKYIGKDDPVAIVRAQSGFPAAGEVVEPFAFPHLVGGWMRGSHNGPLMPVAQRDATPVRFDGPPRVIGLGFQIADCKLVGPIDMFDDPSFDRSRQLASEIAEYMRRHGPFEPHRLPSDEMEYTSLPGVLEKLGDRFEDMD
What is the function of this protein?
Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
What are the official names of this protein?
Fructose-1,6-bisphosphate aldolase/phosphatase, FBP A/P, FBP aldolase/phosphatase.
What is the protein family that this protein belongs to?
Belongs to the FBP aldolase/phosphatase family.