PharMolix/UniProtQA huggingface dataset:
Protein: COBT_RHILW
Sequence: MSVSGLPFDDFRTLLRDLPGPDARALVTARERDAQLTKPPGALGRLEEIAFWLAAWTGRTPAVNRPLVAIFAGNHGVTRQGITPFPPAVTQQMVENFAAGGAAINQICVAYDLGLKVFDLALDYPTGDITEEAALSERDCAATMAFGMEAIAGGTDLLCIGEMGIGNTTIAAAINYALYGGSARDWVGPGTGSEGEMLERKIAAVEKAVELHGDHLDDPLEIMRRLGGREIAAMAGAILAARMERIPVLIDGYVATAAAAILKAANPSALDHCLIGHVSAEPGHLRAIEMLGKTPLLALGMRLGEGTGAALAAGIVKAAAACHSGMATFAQAGVTNKD
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: TALB_SALTI
Sequence: MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSSDRAQQVVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRIIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVYLISPFVGRILDWYKANTDKKDYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEILELAGCDRLTIAPALLKELAESEGAIERKLSFSGEVKARPERITEAEFLWQHHQDPMAVDKLADGIRKFAVDQEKLEKMIGDLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase B.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_AQUAE
Sequence: MISENLFSAKSLEYLEKAKEIARENKDTKVDTDHLLIALLLDEKSPLSKYIEKRGIDRKEFLKRVSEYLENLNKQLEKAIEAEAQNLINLRTQIMEVKSNIGNVQTELSKIRKAKERILRELEYARRYGDWWTAETLELELRQLEATEQSIRRQLEQVEKSLSTVFAPEDVKAFLENKLSIDGLIRKALEKSPLIEQVKELGISPDRIIDKVAEKVFGKKPTFDYSQYLTQVLEKAQDKAVSEGEAQVQPSHISAALIEAKDTIGGKLINQVLGGEKEMKKDVTQELKEEEKSPLERFGVNLNELARQGKLDPVIGREREINQVIEILLRRTKNNPVLVGDPGVGKTAIVEGLAQRIVNKEVPPELQDKEIWSIDMASLLAGSKYRGEFEERLKALLDEVKEKGNVILFIDEIHTVVGAGAAEGAVDAANIMKPALARGEIRVIGATTVDEYRKYIEKDPALERRFQPVFVDEPTEEQTIEILKGLRPRLEQFHKVKISDEAIEAAVKLTKRYVTFRRLPDKAIDALDQAAARKKLKVIGTPPEIQEIERKIKALEEQIIEANLKGDYEKEAQLKIEKAKLEKEKQELLGKVGGVEAKIAELKKKIEELDEKIKEAAEKGDYEKEAELKIEKAKLEKELKKLEQEKSKELVVTWDDVAEVVSEWTGIPVSRLKEEEMQKLLKLEDELHKRVVDQEHAVKAVAEAIRRARAGLKDPKRPIASFLFLGPTGVGKTELSKALAELLFGDEDALIRLDMSEFKEEHSVAKLIGAPPGYVGYEEGGKLTEAVRRKPYSVILLDEIEKAHPRVLDLFLQVLDDGRLTDSHGRTVDFRNTVIIMTSNIGSQYLLNIPVDADEETLNREFEKAKEKVLEELKLYMRPEFINRIDEIIVFKPLTMRELSKIIDLLIANVNKRLAERNIKIELTEEAKKELVRRGYDPAFGARPLKRTIQKYVETPLADKIIRGEIKDGMTVVVDYKDGEFVFIPKEEYEKQKAEVSASSEEKKES
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADEC_ENTFA
Sequence: MNVDVLLKNVWLYQTVTQTFVQRNVAIKNDKFYYIYEEENVNLQPQKTINAENQWMIPGLIDAHMHIESSMTTPTIFSKAVVRYGVTTVIADAHEMANVFGLEGLKAFMAAETELDIFHAIPSSVPSTTPELETTGGIIGLAEVAELLKEPKVICLGEAMNFKGISYEPDSLIRQIIDLCQKQRPTMPLEGHCPKIEDQELADFLYSGITSDHTHQFPKTLKEKIEAGVFIQFQNKSITPENIQVIVDNDFYNYASIITDDVMADDLLKGHLNENVKKAVHAGLPIEKAIYMATYTPAKRMGLHDRGEIAPGKKADFLLLNDLESFDINTVYKSGKVVFEKGEPFHYPEKIEEFPATYQQTIQCKKLTEEDLLLKVATTKETVRCNVIQKQEIGTFTERITKEIPVENGLLQWQKANCALLIVMERYGKNGNISFSLMDQPLSEKGAIATTWAHDHHNLMVMGNTIEDILLAQNELLAMQGGYLVASDQQVMATCPLPIGGILSQAPIEQLGASLQKVRQAMQALGYQNMNEIMSFSTLSLPVSPAIKVTDFGMMDTKSQRFYPLVFPEDGVLLHENTH
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: BICL1_HUMAN
Sequence: MSAFCLGLVGRASAPAEPDSACCMELPAAAGDAVRSPAAAAALIFPGGSGELELALEEELALLAAGERPSDPGEHPQAEPGSLAEGAGPQPPPSQDPELLSVIRQKEKDLVLAARLGKALLERNQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREGEWEGRVSELESDVKQLQDELERQQIHLREADREKSRAVQELSEQNQRLLDQLSRASEVERQLSMQVHALREDFREKNSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEENDLLQGTVEELQDRVLILERQGHDKDLQLHQSQLELQEVRLSCRQLQVKVEELTEERSLQSSAATSTSLLSEIEQSMEAEELEQEREQLRLQLWEAYCQVRYLCSHLRGNDSADSAVSTDSSMDESSETSSAKDVPAGSLRTALNELKRLIQSIVDGMEPTVTLLSVEMTALKEERDRLRVTSEDKEPKEQLQKAIRDRDEAIAKKNAVELELAKCRMDMMSLNSQLLDAIQQKLNLSQQLEAWQDDMHRVIDRQLMDTHLKERSQPAAALCRGHSAGRGDEPSIAEGKRLFSFFRKI
What is the function of this protein?
Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin.  Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track).  Predominantly recruits 2 dyneins, which increases both the force and speed of the microtubule motor.  Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth.  Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis.
What are the official names of this protein?
BICD family-like cargo adapter 1, Bicaudal D-related protein 1, BICD-related protein 1, BICDR-1, Coiled-coil domain-containing protein 64A, CCDC64A.
What is the protein family that this protein belongs to?
Belongs to the BICDR family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes around the centrosome.
Protein: LEU3_DESVH
Sequence: MHMNICLLPGDGIGPEIVAQGTKVLDAVARRFGHTVSTSSALIGGAAIDATGSPLPDATVEACRTSDAVLLGAVGGPKWDDLPSEKRPEKGLLGIRKALGLFANLRPAALFPELAGACLLRADIAAAGLDLVVVRELTGDVYFGQPAGIETRDGLRTGFNTMIYDEDEVRRIARVAFDTARARKRRVCSVDKANVLATSRLWREVVEEVARDYPDVELSHMYVDNAAMQLVRWPAQFDVIVTGNLFGDILSDEAAVITGSIGMLPSASMGSGGPALFEPIHGSAPDIAGQDKANPIATILSVGMMLRLGFGLAAEADAIDAAVRRVLAEGYRTGDIMENGRTLVGTVSMGNLIAERI
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_SYNR3
Sequence: MIVAGVDEVGRGCLFGPVWAAAVILKAEAFDRLPALGVTDSKALSAKRRQALLPEIHSHCLSYGLGQASAACIDAVGIRAATELAMCRALQRLCHSPDHVLVDGSLPLRPWPGSQETVVAGDSHCLAIACASILAKEGRDALLQRLDQRWPGYGLASHKGYGTKAHRTALLQWGPTPLHRLSFLAPELKGGSPAGASSGNLE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_BACHK
Sequence: MAVKIRLKRMGAKKTPFYRVVVADSRSPRDGRFIEEIGTYNPVAQPAEVKINEEAALKWLGNGAKPSDTVRNLFSNQGIMEKFHLSKQGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MNMG_PROM1
Sequence: MITKQSSNESFDVIVVGGGHAGCEAALTSARLGLNTALFTLNLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADLTALQKRVLNASRGPAVRALRAQTDKRSYAHEMLKILQNTPNLKIREAMVTGLEIEHYPNQIDQKTPEIQERIGFIKGIKTYFGSVFHAKAVVLTTGTFLGGRIWIGNQSMSAGRAGEQASEGLTEELKKLGFTTDRLKTGTPARVDRRTIDLDSLDEQLSDASDKFFSFDPLSWKSGEQMSCHITRTTKETHQLIKNNLHLTPIYGGFIDSKGPRYCPSIEDKIVRFADKDSHQIFLEPEGRDTPEMYVQGFSTGLPENLQLELLRTLPGLQNCVMLRPAYAVEYDYIPATQLEATLETKRISGLYSAGQLNGTTGYEEAAAQGLVAGLNAARLVNNKEGIIFERESSYIGTMIDDLVTKDLKEPYRVLTSRSEYRLILRGDNADRRLTPLGYQLGLIDERRWNIFNAKQQLINQEKERLDKERIKESDKCAKEIFSSTGTPIKGSLTLANFLRRTNIHYKDLITYNLTTQSIPLDVEEAVEIDIKYSGYLERQKAQINQLKQQSKKLLPKNLNYNNIETLSKEAREKLTISQPKSLGHAAQVPGVSKADLTALLVWLKIEKMKKVKRKDSLQITN
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VERC_CLORO
Sequence: MLSEMLGEIAALPMVSLLGAALIVVSVLGRRLLVSNIAWAITGQTPAKSLAKRSRLPGLPFKFPNGQGTEKFFGGRSAARRWRIQYGPIYAIWAGLKREVVLSTPEHVQAFYKDSHLHVKATDNNSGWLFAELLGSCVGVVSQGRWKRVRRPFEHPFSRPESLTRPKAFIHEARDYFAVLNPNIQELTINTSNDLKHCPFFMVASIFFGIHTTAQRDELKQLGPPREELFRHAFMGGMNRYAITKYLPGSALALLRQFQGKWEGFVKAAYNRSIQTGDGTIVPLFEAVNRGEMSMQELLQTLDESLFANLDVTAHAVSWNVIRIAHHQDIQQKVRIEIQANNNSEKSYENYVCRDDTLLAACVLETSRLHPVLPFSNPEAAEEDKIVGGYIIPQTDVIVDTHAINIDNPHWVDSNSFDPHRHLGQKDSSRRYNMWRFGFGPRQCLGKNVADIILRIILCEMLNTYELGLLEEEGITGVKLQPDSWIGLPNGVVQMTPLKLDE
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of 11'-deoxyverticillin A, one of the dimeric epipolythiodioxopiperazines (ETPs) from the verticillin family that act as mycotoxins (PubMed:28376389).  11'-deoxyverticillin A is required for normal conidiation (PubMed:28376389).  The nonribosomal peptide synthetase verP is speculated to be responsible for condensation of amino acids to form the carbon skeleton of verticillin, whereas the cluster-specific tailoring enzymes are involved in further modifications leading to the production of 11'-deoxyverticillin A (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase verC, Verticillin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YBEY_SYNWW
Sequence: METMIINQQNKINYTKEMQQVILNVANAVAKMVKLSPNTELSVMIVDNSYIKELNLIYRGENNPTDVLSFAMNELSEEEMDLDLPGEVNVLGDIVVSLEKAVSQSEEYGHSAERELGYLIAHGMLHLLGYDHENEEERNLMRNLEERIMHKVKLER
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTF64_ARATH
Sequence: MASSSSQRRCVFVGNIPYDATEEQLREICGEVGPVVSFRLVTDRETGKPKGYGFCEYKDEETALSARRNLQSYEINGRQLRVDFAENDKGTDKTRDQSQGGPGLPSTTTVTESQKQIGGPVDSNMHQPVGLHLATTAASVIAGALGGPQVGSQFTQSNLQVPASDPLALHLAKMSRSQLTEIISSIKLMATQNKEHARQLLVSRPQLLKAVFLAQVMLGIVSPQVLQSPNIVQAPSHMTGSSIQDAQLSGQNLLPPLAQRSQQLSRAPHSQYPVQQSSKQPFSQIPQLVAQPGPSSVNPPPRSQVKVENAPFQRQQVVPASTNIGYSSQNSVPNNAIQPSQVPHQALPNSVMQQGGQTVSLNFGKRINEGPPHQSMNRPSKMMKVEDRRTTSLPGGHVSNSMLPNQAQAPQTHISPDVQSTLLQQVMNLTPEQLRLLTPEQQQEVLKLQQALKQDHMMQPS
What is the function of this protein?
One of the multiple factors required for polyadenylation and 3'-end cleavage of pre-mRNAs (By similarity).  This subunit is directly involved in the binding to pre-mRNAs, especially on the 3' non-coding region (PubMed:12379796).  Required for the targeted 3' processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed:17008405, PubMed:19965720).
What are the official names of this protein?
Cleavage stimulating factor 64, AtCstF-64, AtCstF64, CF-1 64 kDa subunit, Cleavage stimulation factor 64 kDa subunit, CSTF 64 kDa subunit, Protein ENHANCED SILENCING PHENOTYPE 1, Protein SUPPRESSORS OF OVEREXPRESSED FCA 19, SOF19.
What are the subcellular locations of this protein?
Nucleus.
Protein: FER2_EQUAR
Sequence: AYKVTLKTPDGDITFDVEPGERLIDIGSEKADLPLSCQAGACSTCLGKIVSGTVDQSEGSFLDDEQIEQGYVLTCIAIPESDVVIETHKEDEL
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin-2, Ferredoxin II.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PAFA_RHOOB
Sequence: MQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDNLIQLVNHDRAGERVLEELLIDAEQRLAEEGIGGDIYLFKNNTDSAGNSYGCHENFLVARAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATFCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMSESTTMLKVGTAALVLEMIEAGVSFRDFALDNPIRAIREVSHDVTGRRPVRLAGGRQASALDIQREYHARAVEHLQNRDPDPQVTQVVDLWGRMLDAVETQDFAKVDTEIDWVIKRKLFQRYQDRHGFELADPKIAQLDLAYHDIKRGRGVFDVLQRKGLVKRITEDETIEAAVDTPPQTTRAKLRGEFITAAQEAGRDFTVDWVHLKLNDQAQRTVLCKDPFRSVDERVERLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: HFA6A_ARATH
Sequence: MDYNLPIPLEGLKETPPTAFLTKTYNIVEDSSTNNIVSWSRDNNSFIVWEPETFALICLPRCFKHNNFSSFVRQLNTYGFKKIDTERWEFANEHFLKGERHLLKNIKRRKTSSQTQTQSLEGEIHELRRDRMALEVELVRLRRKQESVKTYLHLMEEKLKVTEVKQEMMMNFLLKKIKKPSFLQSLRKRNLQGIKNREQKQEVISSHGVEDNGKFVKAEPEEYGDDIDDQCGGVFDYGDELHIASMEHQGQGEDEIEMDSEGIWKGFVLSEEEMCDLVEHFI
What is the function of this protein?
Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
What are the official names of this protein?
Heat stress transcription factor A-6a, AtHsfA6a, AtHsf-19.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class A subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPEH_THERP
Sequence: MKSLGRHVIVELWGCQNIDSLQAVEEAIRDAVAATNATLRDLQVFPWEPYNGVSGIAILSESHLSIHTWPELGYAAVDVFTCGEHTNPEAAIPVLRERFRPQRMEVMQVSRGMIVD
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: P34_LIYV9
Sequence: MIMMSPLYALTKQCVIDTAYRLAVPTQHCAIYTVACRILFLSVGFMTIVKLCGFKMDTSSFIASIEKDNLMDCLISLVEMRDRLRLCNDFPILNYGVNILELLIGKRLNKINNLKNCYVIRELITINISKEWVGKQALKVGLHCFLNLSQADSRHVKYLLSDKESLNKMNFSRYYVPKVVTDLYLDLIGVLYVNTGYNIDLVEKFIFDKLEFLVYDGEEGFKSPQVEYNDICTVNNLKPIIKYNRWHTDGSIVIECGDVIGKGINKTKKKFAINDAKAEFVKNFKAKNKNNE
What is the function of this protein?
Acts as a ssRNA-binding protein that may be involved in targeting RNA2 to replication sites or facilitating RNA2 replication.
What are the official names of this protein?
RNA-binding P34 protein, P34.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass membrane protein. Note=Probably localizes to virally-induced ER rearrangement structures.
Protein: HSP41_SOYBN
Sequence: MRLQQLNLFFLLLCVAKANGSLLPFMDPPITLLADLWSDRFPDPFRVLEHIPFGVDKDEASMAMSPARVDWKETPEGHVIMLDVPGLKREEIKVEVEENRVLRVSGERKKEEEKKGDHWHRVERSYGKFWRQFRLPQNVDLDSVKAKLENGVLTLTLDKLSPGKIKGPRVVSIAGEDHQQGNLNNDGAKQEL
What are the official names of this protein?
22.0 kDa class IV heat shock protein.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Note=In the endomembrane, probably in the lumen of endoplasmic reticulum.
Protein: AAEB_ECO57
Sequence: MDIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEKLCIWQAPPQVTEPVHRLAGMLHKYQHALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IORB_BREDI
Sequence: MKTVLPSVPETVRLSRRGFLVQAGTITCSVAFGSVPAAAGDTAESTPSIAAVSPNVWVRVHADGIVDIVCPAVELGQGAHTALPRFVAEELDADWDRVRVQQAGASDKVYGNPLAWGTQFTAASRTTVGYFDVLRVAGAQARFVLVQTAARRWSVPADQLETQKGVVLHRRSRRSATYGELVASVQVPESFPHFFARNEATQPADDYFGAAPPSVVAQAAGPASGAIALKHRSTYRLIGKDAPRKDIPPKVNGQACYGMDVQVPGMLYAMVETGPVAGMAPERVDDGAARQVPGIHHVLSLPHGVAVVGRDIFAVRAARARLLVNWKANPDKQSYDSGQVLDEFSDLCRNGIERNAVQAWKQGELSSIDAVFARPDVRIESFEMQSDLVYQAPMEPQSAVIQPHADGSAEAWVGTQWPTVEQGFAAGILGIAPDKLTMHLPLVGGGFGRRLEPGALVDAAHIVRAIGKTVKVIWSREDDLKRNPFRQALACRVEAAVLEKDQRILALRHTVAADSWLARLFPQYFNAYQQTDPGNWIGGMVAYDVPLQRIDALTPRRSVDVCYMRGIGVAQVKFAQESLVDQIARRLNADPVDFRLAHLNTSPRGAAVVRTVAEMSDWKRRSADAGGGMALGLAYTPYSNAHVALVSEVHFNRSENTLSVSRVWCAVDVGMVAQPDIVKAQMEGGIIQGLSVALMERVQVAKGVLQHSNFHDYPMLRMSQVPQIHVRLVETDQAMAGVAELGLLQIGPAINNAFARITGQHLRSLPMRPALAQMKRSGPTA
What is the function of this protein?
Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline.
What are the official names of this protein?
Isoquinoline 1-oxidoreductase subunit beta.
Protein: MNME_ECOLI
Sequence: MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPRYADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVRNKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Partially associated with the inner membrane.
Protein: UTY_PANTR
Sequence: MKSCGVSLTTAAVAFGDEAKKMAAGKASREGEEEPLSLTVEEREALGDMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTLSSAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIPYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFVSYRQSIDRSEASADTWCSIGVLYQQQNQPIDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCLTPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAIADSSLPTNSVSNRQPHAALTRVSSVSQPGVRPACVEKLLSNGAFSAGCIPCGTSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHSHTDLNSSTEEPWRKQLSNSTQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKSNEHLTLPSNSVPQGDADSHLSSHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDPSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGNSQSSTKVDLPLVSHRSTSQIIPSMSVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHIVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLSLPNSWNYRHLPSCPTNFCIFVETGFHHVGQAHLELLTSGGLLASASQSAGITGVSHHAR
What is the function of this protein?
Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3.  Has relatively low lysine demethylase activity.
What are the official names of this protein?
Histone demethylase UTY, Ubiquitously transcribed TPR protein on the Y chromosome, Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein, [histone H3]-trimethyl-L-lysine(27) demethylase UTY.
What is the protein family that this protein belongs to?
Belongs to the UTX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF1_LACDB
Sequence: MAKDDVIEVEGKVVDTLPNAMFKVELENGATILAHVSGKIRMHYIRILPGDRVTVELSPYDLTKGRITYRFIK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKBP2_BOVIN
Sequence: MRLSWVLTVLSICLSALVTATGTEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRSEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP2, PPIase FKBP2, FK506-binding protein 2, FKBP-2, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: RVE5_ARATH
Sequence: MVSVNPRPKGFPVFDSSNMSLPSSDGFGSIPATGRTSTVSFSEDPTTKIRKPYTIKKSRENWTDQEHDKFLEALHLFDRDWKKIEAFVGSKTVVQIRSHAQKYFLKVQKSGANEHLPPPRPKRKASHPYPIKAPKNVAYTSLPSSSTLPLLEPGYLYSSDSKSLMGNQAVCASTSSSWNHESTNLPKPVIEVEEPGVSATAPLPNNRCRQEDTERVRAVTKPNNEESCEKPHRVMPNFAEVYSFIGSVFDPNTSGHLQRLKQMDPINMETVLLLMQNLSVNLTSPEFAEQRRLISSYSAKALK
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Protein REVEILLE 5.
What are the subcellular locations of this protein?
Nucleus.