PharMolix/UniProtQA huggingface dataset:
Protein: CPNA1_ARATH
Sequence: MASANALSSASVLCSSRQSKLGGGNQQQGQRVSYNKRTIRRFSVRANVKEIAFDQHSRAALQAGIDKLADCVGLTLGPRGRNVVLDEFGSPKVVNDGVTIARAIELPNAMENAGAALIREVASKTNDSAGDGTTTASILAREIIKHGLLSVTSGANPVSLKRGIDKTVQGLIEELQKKARPVKGRDDIRAVASISAGNDDLIGSMIADAIDKVGPDGVLSIESSSSFETTVEVEEGMEIDRGYISPQFVTNPEKLLAEFENARVLITDQKITAIKDIIPILEKTTQLRAPLLIIAEDVTGEALATLVVNKLRGVLNVVAVKAPGFGERRKAMLQDIAILTGAEYLAMDMSLLVENATIDQLGIARKVTISKDSTTLIADAASKDELQARIAQLKKELFETDSVYDSEKLAERIAKLSGGVAVIKVGAATETELEDRKLRIEDAKNATFAAIEEGIVPGGGAALVHLSTVIPAIKETFEDADERLGADIVQKALLSPAALIAQNAGVEGEVVVEKIMFSDWENGYNAMTDTYENLFEAGVIDPAKVTRCALQNAASVAGMVLTTQAIVVDKPKPKAPAAAAPEGLMV
What is the function of this protein?
Binds RuBisCO small and large subunits and is implicated in the assembly of the enzyme oligomer.  Involved in protein assisted folding.  Required for proper chloroplast development.
What are the official names of this protein?
Chaperonin 60 subunit alpha 1, chloroplastic, CPN-60 alpha 1, Protein SCHLEPPERLESS, RuBisCO large subunit-binding protein subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FTSQ_NEIG1
Sequence: MWDNAEAMERLTRWLLVMMAMLLAASGLVWFYNSNHLPVKQVSLKGNLVYSDKKALGSLAKEYIHGNILRTDINGAQEAYRRYPWIASVMVRRRFPDTVEVVLTERKPVARWGDHALVDGEGNVFEARLDRPGMPVFRGAEGTSAEMLRRYDEFSTVLAKQGLGIKEMTYTARSAWNVVLDNGITVRLGRENEMKRLRLFTEAWQHLLRKNKNRLSYVDMRYKDGFSVRHAPDGLPEKESEE
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.  May control correct divisome assembly.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: LEU3_NEIMB
Sequence: MTKHIAILRGDGIGPEIVAETVRVLDKLIAQGLDAGYEYAPLGGEAYDEYGHPYPEFTQNLCRKADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFANLRPAVLYPELANASTLKPEIVAGLDILIVRELTGDIYFGEPRGIRVLENGEREGYNTMKYSESEIRRIAHVAFQSAQKRSKKVCSVGKANVLETTELWREIFEEIGKEYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGLYEPSHGSAPDIAGQNKANPLATILSLAMLLRYSLNDEARAQQVENAVQKVLQQGLRTSDIYEEGTKLVSCSEMGDAVLAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOMB_BOMVA
Sequence: MSAIPLNRILPLGFLLIFSFISLSSCMEFVEDPNNQGGLNLQQRLGNQWAVGHLMGKKSLQDTDFEEMESFAKRNVENMKAESERELRHAQLVVRNILEQYLKNMQN
What is the function of this protein?
Stimulates smooth muscle contraction.  Role in induction of hypothermia, stimulation of DNA replication and release of many gastrointestinal hormones.  Possesses insulin-releasing activity.
What are the official names of this protein?
Bombesin.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YFKJ_BACSU
Sequence: MISVLFVCLGNICRSPMAEAIFRDLAAKKGLEGKIKADSAGIGGWHIGNPPHEGTQEILRREGISFDGMLARQVSEQDLDDFDYIIAMDAENIGSLRSMAGFKNTSHIKRLLDYVEDSDLADVPDPYYTGNFEEVCQLIKTGCEQLLASIQKEKQL
What is the function of this protein?
Dephosphorylates the phosphotyrosine-containing proteins.  Involved in ethanol stress resistance.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase YfkJ, LMPTP.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Protein: AROE_SHEPC
Sequence: MTDKYAVFGNPISHSKSPFIHGQFAAPTQELLTYEAILAPVDGFEASLTAFFNAGGKGANVTVPFKEQAFALCDSLSPEAKLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQGKRVLLIGAGGAARGCILPLLNAGIAQLTISNRTHTKAQLLVDIFTSVDNGAFANRVTAVEMNELVGEFDIIINSTSASLAGELPPVPAHIITPQTVCYDMMYGASVTAFNQWALSQGAAKVIDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLKAEPK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: Y1056_PYRAR
Sequence: MEILPVGEESLGVRSMCLYVETRDVRILFDAGVSLAPRRFGLPPHPRELERARSVRGEIVRLAQQADIITVSHYHRDHFTPWYPSVYMATDGETYKKVYGGKKVLMKSPADLNWSQRRRHYGLAKALQEAGAKAVYADGGEWRIGGTVIRASPPLWHGPAGSKTGRVIAFAVSDGEERLVFVPDVEGPVEPEPVAFLEEVKPTVVVVGGPPTYLGWELERALQRLTEIIDIGPHTLVLAHHLLRDLAWREKIEAVLQRAEKRGVRVATYAGLLGRKDELLEAMRRDLYAAEPAAAQPAEEGIDEGD
What are the official names of this protein?
UPF0282 protein Pars_1056.
What is the protein family that this protein belongs to?
Belongs to the UPF0282 family.
Protein: SC4AA_TETNG
Sequence: MATILPPPGTAMFRHFTPQSLAKIERLKEETKKAAEVGPREEEEPPTPNPDLEAGKGLPRIYGEPPAELLSTPLEDLDPFYKAQKTFVVITKGNTIYRFNAEPACYILSPFSRVRRGAIKILIHSLIMITILSNCVFMTMSNPPAWSKTVEYVFTGIYTFEATVKVLSRGFCVGPFTFLRDPWNWLDFMVISMAYITEFVDLGNVSALRTFRVLRALKTITVIPGLKTIVAALIQSVKKMVDVMILTVFALSVFALVGLQLFMGNLRHKCIRWPVAANQSAFEPFNSTVGNDTTGLNDTLFSNITFDFTEYIENAENQYFLPGSADALLCGNSSDAGRCPEGYECMKAGRNPNYGYTSFDSFGWAFLALFRLMTQDCWENLFQQTLRAAGKTYMLFFVVVIFLGSFYLINLILAVVAMAYEEQNQASQQEAREKEEEFQWLLEQLKNQEQAQVLGSRASPTSEKSVSLTTSDAPDEDQSLENDEALKDCNGRFIPRLIVRAPTMKESAADYESGEKVEGSTHSRLHVEDAGLKQRSASAVTVLTAAAVEELEEAQRPCPPIWYKFANMFLKWNCCQPWAVFKEWVHFVVMDPFVDLAITICIVLNTLFMAMEHYPMTQEFDYMLSVGNLVFTGIFAAEMFFKLIAMDPYYYFQVGWNIFDSIIVTLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGSSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKISTECELPRWHMNDFFHSFLIVFRILCGEWIENMWACMEVAGAGMCLVVFMMVMVIGNLVVLNLFLALLLSSFSGDNLSIGEDDGEMNNLQIAIGRITRGGNWLKTLVIRTVLQLLGREQGKPAEEDPAEEGEQKPERIEMNHLDQLKTADGIANCLVGRQPSGTAADGESVINVPIALGESDSEHQSEGDDYQEDDVDSESTCEENEHGSNSMEDGFGVLQHVKLMGALTDGESSVCSTADYRPPEPETLEEEEEEPEPLEPEACFTDNCVKHWPCLNVDVTQGQGKKWWNLRKTCFTIVEHDWFETFIIFMILLSSGALAFEDIYIERRRTVKIILEFADKVFTFIFVLEMVLKWVAYGFKTYFTNAWCWLDFFIVDISLISLSANLMGLSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIFNVLLVCLIFWLIFSIMGVNLFAGKFYHCINTTTQELFPISVVNNKSDCMAVQEATQEARWVNVKVNYDNVGKGYLSLLQIATFKGWTAIMYAAVDSREVEEQPSYEINLYMYIYFVIFIIFGAFFTLNLFIGVIIDNFNQQKRKLGDKDIFMTEEQKKYYEAMKKLGSKKPQKPIPRPTNLIQGMVFDFISQQFFDIFIMVLICLNMVTMMVETDDQSPEKEDFLFKVNVAFIVVFTGECMLKLIALRQYFFTNGWNIFDFVVVILSIAGTMLSDLIEKYFVSPTLFRVIRLARIGRILRLIKGARGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKEAGIDDMFNFETFGSSIICLFQITTSGGWDQILLPILNKEPPDCDPTLENPGTDVKGNCGNPMVGMMFFCSYIIISFLVVVNMYIAIILENFNVAQEESGDALCEEDFEMFNETWEKFDTGGTQFIEYSQLSDFCDTLQEPLRVAKPNRLRLIEMDLPLVIGDRIHCVDVLLAVTQEVLGDTIEMVAMRESIEAKFNLNNPTSVSYAPITTTVRQKEEEMAAVVIQRAYRNHLHKRGIHHAAYIQRSKTGRKADSEDAPEKEGLLAEKMGALYGREAEGRERAPDPETPPRCSGARCGPEPPEPNVIVVPVEITNEFLLHSAPPTHTSYPRRQT
What is the function of this protein?
Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient.  Alternates between resting, activated and inactivated states.  Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.
What are the official names of this protein?
Sodium channel protein type 4 subunit alpha A, Voltage-gated sodium channel subunit alpha Nav1.4a.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERPA_LEGPA
Sequence: MASVDVSQNTSDIHFSVSAADKVAELIKEEDNSNLNLRVSITGGGCSGFQYGFSFDEQINDDDTIIIQQCSDGKSSVKLLIDSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGSSFSIGDEDVL
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: CSI2_YEAST
Sequence: MRLPEISIWKVILLLHLFALQEFQLVSAANLPSLSSSTKAADSSSKGSSSAKTTTSLGKSSVTSKDVSSSHNVTSSTKMPKITTSASTSLYTNSSLWSNNSVISTSSITPSSVYIPVTDGNKFLYQAHHPNGTVFIAFAGCLGAILLSLTGAWIALNIKSWRSARKENKLRNLENQYQHDPFYFQTNINDDESETSSHSDDSDISEKVLKNNSSRMSLYTLGSTSVLNLLNNKTDANDNFRSSMFISPTEILQSDANNSNTWSQSNESAIYDSLSSTPREPGATQILGKFTDSTNPFNYTSYNLSPDSEDRSTPKSNVSQGKVKKYRPPSVHLDQLLDGKE
What is the function of this protein?
Appears to be a structural component of the chitin synthase 3 complex.
What are the official names of this protein?
Chitin synthase 3 complex protein CSI2.
Protein: BAIG_CLOSV
Sequence: MSTVANPNYKKGFVPFAIAALLVSLIGGFTAVLGPAFVADQGIDYNNTTWISLALAMSSAACAPILGKLGDVLGRRTTLLLGIVIFAAGNVLTAVATSLIFMLAARFIVGIGTAAISPIVMAYIVTEYPQEETGKAFGLYMLISSGAVVVGPTCGGLIMNAAGWRVMMWVCVALCVVVFLICTFSIKKTAFEKKSMAGFDKPGAALVVVFFSLFLCIPSFGQNIGWSSTAFIAAAAVALVALFILVMVEKKAKSPIMNGKFMARKEFVLPVLILFLTQGLMMANMTNVIVFVRYTQPDNVIISSFAISIMYIGMSLGSVIIGPVADKKEPKTVLTFSLVLTAIGCALMYLFKADSSVAIFAASLGILGFGLGGNATIFMKVALSGLSSEVAGSGTGTYGLFRDISAPFGVAVFVPMFANGVTANIAKYASGGMEEGAATVKAAISSIQTLTLVELGCIVVGIILVRMLPRIYQKKEA
What are the official names of this protein?
Bile acid transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y151_ACET2
Sequence: MSNNETMMFNVEKEKVNEARELLVSVYKALKEKGYNPINQIVGYILSGDPTYITNHLDARSSIRKVERDELLEEILRCYLEECIGKEGSV
What are the official names of this protein?
UPF0297 protein Cthe_0151.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: KDPC_STAAR
Sequence: MNTIRNSICLTIITMVLCGFLFPLAITLIGQIFFYQQANGSLITYDNRIVGSKLIGQHWTETRYFHGRPSAVDYNMNPEKLYKNGVSSGGSNESNGNTELIARVKHHVKFDNSNVTIDAATSSGSGLDPHITVENALKQAPRIADARHISTSRVADLIQHRKQRGVLTNDYVNVLELNIALDKMKD
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MUS81_GIBZE
Sequence: MADADSANPQFLEWVKEWLDLARERNSKGVTTYRTAYNSLKACPISFEHPAQLQQLKGFGPKLCERLEQQLKKHCEQNGLPMPPHPRSRKAAPVTSDENGEGSSKPAKKARKQKAYVPALRSGAFALVVGLSTLDEDTATGMTKAELIEVAQPYCDASFSAPSDPTKFYTAWNSMKTLLQKELVYERGRPLRRYALTDEGWEVAKRIKDTDHWQAEKDRTKDPTSAQPVIPNFQPGAISRQKSPSVEIAEPAQALSEYQNVVADGLTTSDDASLPNFTPILLPPGTFTVQLVLDVREVRAKTDRDYMQEELAKQGAKPIMRSMELGDAQWVAKCNDPNLLSSQGAEGDEVVLDWIVERKRLDDLIGSIKDGRFHEQKFRLQRSGVKKVIYIIEEIGMDPEVINRYAEAVRSAIASTQVVNGYFVKRTNKMDDTIRYLTRMTAMLKRTYESRSLHVIPTKVLTSQNYLPLLKHLRESISPDWYITYPAFSSLASKSESITLRDVFLKMLMTIKGVTGEKALEIQKCWKTPYDFVKAFEACGPGEQGLKRKRELVFSQTSHLVGRKKFTKPLSTKIAEVWGNT
What is the function of this protein?
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.  Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions.  May be required in mitosis for the processing of stalled or collapsed replication fork intermediates.  May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI) (By similarity).
What are the official names of this protein?
Crossover junction endonuclease MUS81.
What is the protein family that this protein belongs to?
Belongs to the XPF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBEY_BLOPB
Sequence: MTSNQVIIDLQLACKNLHGLPNRKMFQSWVSAIFSIYKKKIELTVRIVDIKEMHYLNWYYLKKDCPTNVLSFPFTPPLGMKSPLLGDVVLCRQIIEYESKEKNVPGRSHWAHMIIHGSLHLLGYNHIVDKEAILMQRVERNILQKCGYRTCCHVAHR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_CUPTR
Sequence: MPPKPRIALIAHDHKKDDIVAFAARHRAFLSQCELLATGTTGGRLIDEVGLDVTRMLSGPWGGDLQIGAQLAEGRVSAVVFLRDPMTPQPHEPDINALVRACDVHNVPCATNVASAELLLAGLARENGAAQAG
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: AMPA_CHLCV
Sequence: MVLFHSQASCSKRIEADAIILPFWKLKDKVKCAASIAKEYESLYQVALDNFSAKSREVELIYSCGQGKEKRIVLLGLGKNEELSSQEVLEAYAKATRLLRKAKCTTVNVVLPTISELRISIEDFLTNLTSGILSLNYNYPKYTKESSNDPLLTKVNVLGIVPKIADRIFRKEENIFEGVYLTRDLVNGNADEVTPQKLANIAKGMAKEFPSMDVKILNKDAILKEKMGLLAAVAKGSAVDPCFIVLTYQGKPKSKDHTVLIGKGVTFDSGGLDLKPGKAMLTMKEDMAGAATVLGILSGIAALELPVNVTAIVPATENAIDAAAYKMGDVYTGMSGLSVEIGSTDAEGRLILADAITYALKYCNPTRIIDFATLTGAMVVSLGEDVAGFFSNNDVLAQDLSEASAETSEALWRLPLVEKYNKALHSDIADMKNIGSNRAGAITAALFLKRFLEDQPVAWAHLDIAGTAYREKDEDLYPKYASGFGVRCLIYYIEKFLSK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_SALA4
Sequence: MKPDAHHVKQFLLRLQDDICQTLSAVDGANFVEDSWRREAGGGGRSRVLRNGGIFEQAGVNFSHVHGDAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYIPTSHANVRFFIAEKPGADPVWWFGGGFDLTPYYGFEEDAVHWHRTARDLCQPFGDDVYPRYKKWCDDYFFLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGNGYTEAYLPIVERRKAMVWGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDWQPEAGSPEAALSEFIQVRDWI
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM147_XENTR
Sequence: MTLFHFGNCFALAYFPYFITYKCSGLSEYNAFWRCVQAGATYLCVQLCKMLFLATFFPTWEGAVGAYDFIGEFMKATVDLADLLGLHLVMSRNAGKGEYKIMVAAMGWATAELVMSRCLPLWVGARGIEFDWKYIQMSIDSNISLVHYMAVAALVWMWTRYDLPTHYRLPVTVLLGLSMYKAFLMDCFVHIFIMGSWTALLLKAVITGVLSLSCLTLFVSLVHGN
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes.  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions.
What are the official names of this protein?
BOS complex subunit TMEM147, Transmembrane protein 147.
What is the protein family that this protein belongs to?
Belongs to the TMEM147 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: AL4A1_RAT
Sequence: MLPPALLRRSLLSYAWRGSGLRWKHASSLKVANEPILAFTQGSPERDALQKALNDLKDQTEAIPCVVGDEEVWTSDVRYQLSPFNHGHKVAKFCYADKALLNKAIEAAVLARKEWDLKPVADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHVVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNVIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPQSLWPQIKGRLLEEHSRIKVGNPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYFVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDEKYRETLQLVDSTTSYGLTGAVFAQDKTIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGERDIPGQPRLVQLWTEPPFTPLAVSPPLGDWRYSYMQ
What is the function of this protein?
Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate.  This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles.  The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity).
What are the official names of this protein?
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, P5C dehydrogenase, Aldehyde dehydrogenase family 4 member A1, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ACCD_CLOBH
Sequence: MLKNLFRKTKYITVSQKNIENYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLCGNHFRIGVKERIKYLFDKDTFKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGKCKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIGLRLPVIIFTASGGARMQEGILSLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRVIEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESPR_MYCTU
Sequence: MSTTFAARLNRLFDTVYPPGRGPHTSAEVIAALKAEGITMSAPYLSQLRSGNRTNPSGATMAALANFFRIKAAYFTDDEYYEKLDKELQWLCTMRDDGVRRIAQRAHGLPSAAQQKVLDRIDELRRAEGIDA
What is the function of this protein?
Virulence regulator that has both architectural and regulatory roles.  Impacts cell wall functions and pathogenesis through regulation of multiple genes, including the espACD operon, which is a key ESX-1 component.  Influences target gene expression positively or negatively, depending on its binding position relative to the genes it controls.  Acts by binding directly to the DNA.  May play a central role in regulating virulence gene expression.
What are the official names of this protein?
Nucleoid-associated protein EspR, ESX-1 transcriptional regulatory protein EspR.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MNMA_PARPJ
Sequence: MSKQKVVVGMSGGVDSSVTAWLLKEQGYDVVGLFMKNWEDDDDSEYCSTRQDWIDVVSVADLIGIDVEAVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLGAETIATGHYARVRQNERNGRFELLKAFDHTKDQSYFLHRLNQAQLSKTLFPLGEIPKTKVREIAEQIALPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTTDGKVVGEHIGLAFYTFGQRKGIGLGGSKDGSGEPWFVAGKDIASNTLYVAQGHDHAWLLSHTLSAGNTSWVAGEPPADGFACGAKTRYRQADAPCTFSSAGSGEGLFELNFDAAQWAVTPGQSAVLYDGDVCLGGGIIEHAVTGQPVAREPQKAALLNAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_CLOK5
Sequence: MHTERQKHIRNFSIVAHIDHGKSTLADRLIEKTGTLTEREMNSQVLDNMELEKERGITIKSQAIRLIYKRKDGGEYVLNLIDTPGHVDFNYEVSRSLAACEGAILVVDATQGIQAQTLANCYLAMEHDLEILPVINKIDLPSARAEEVKEEIEDIIGIEASEAPLVSAKTGLNIEQVLEAIVDKIPSPQGDENAPLKALIFDSNYDSYKGVVCHIRVKEGNIKPGDEIKLMATGKIYEVTETGIFVPNFMPRAELRAGDVGYFTASIKNVRDARVGDTVTGAKNQAKEPLKGYRPVISMVYSGIYPVDGAKYGELKEALEKLQVNDAALNFEPETSVALGFGFRCGFLGLLHMDVIQERVEREFNLDIITTAPSVIYKIGKTDGTVVELTNPTNMPPVSEIKYMEEPIVKASIITPSEYVGAVMELAQNRRGVFRDMQYIETTRVSLNYDIPLNEIIYNFFDVLKSRTRGYASLDYELKGYKSAKLVRLDVLLNGDMVDALSMIVPEERAYDRGRGIAEKLKGIIPRQLFEIPIQAAVGGKVIARETVKAMRKDVLAKCYGGDISRKRKLLEKQKEGKKRMRQVGTVEIPQEAFMAILKTEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PB2_INBP9
Sequence: MTLAKIELLKQLLRDNEAKTVLKQTTVDQYNIIRKFNTSRIEKNPSLRMKWAMCSNFPLALTKGDMANRIPLEYKGIQLKTNAEDIGTKGQMCSIAAVTWWNTYGPIGDTEGFEKVYESFFLRKMRLDNATWGRITFGPVERVRKRVLLNPLTKEMPPDEASNVIMEILFPKEAGIPRESTWIHRELIKEKREKLKGTMITPIVLAYMLERELVARRRFLPVAGATSAEFIEMLHCLQGENWRQIYHPGGNKLTESRSQSMIVACRKIIRRSIVASNPLELAVEIANKTVIDTEPLKSCLTAIDGGDVACDIIRAALGLKIRQRQRFGRLELKRISGRGFKNDEEILIGNGTIQKIGIWDGEEEFHVRCGECRGILKKSKMRMEKLLINSAKKEDMKDLIILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFDQWGYEESPKASELHGINELMNASDYTLKGVVVTKNVIDDFSSTETEKVSITKNLSLIKRTGEVIMGANDVSELESQAQLMITYDTPKMWEMGTTKELVQNTYQWVLKNLVTLKAQFLLGKEDMFQWDAFEAFESIIPQKMAGQYSGFARAVLKQMRDQEVMKTDQFIKLLPFCFSPPKLRSNGEPYQFLRLVLKGGGENFIEVRKGSPLFSYNPQTEVLTICGRMMSLKGKIEDEERNRSMGNAVLAGFLVSGKYDPDLGDFKTIEELEKLKPGEKANILLYQGKPVKVVKRKRYSALSNDISQGIKRQRMTVESMGWALS
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds a wide range of cap structures of target pre-RNAs which are subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: S35G5_GORGO
Sequence: MAGSHPYFNLPDSTHPSPPSGPPSLRWHQRCQPSDATNGLLVALLGGGLPAGFVGPLSRMAYQASNLPSLELLICRCLFHLPIALLLKLCGDPLLGPPDIRGRACFCALLNVLSIGCAYSAVQVVPTGNAATVLKGSSTVCSAVLTLCLESQGLSGYDWCGLLGSILGLIIIVGPGLWTLQEGTMGVYTALGYVQAFLGGLALSLGLLVYRSLHFPSFLPTVAFLSGLVGLLGSVPGLFVLHTPVLPSDLLSWSCVGAVGILTLVSFTCVGYAVTKAHPALVCAVLHSEVVVALILQYYMLPETVAPSDIMGAGVVLGNITIIPAWNLSCERTGKVEE
What are the official names of this protein?
Solute carrier family 35 member G5, Acyl-malonyl-condensing enzyme 1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the SLC35G solute transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.