PharMolix/UniProtQA huggingface dataset:
Protein: RPA2_PONAB
Sequence: MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQAIPPFEFAFKDERISFTILDAVISPPTVPKGTICKEVSVYPAECRGRRCTYRGKLTADISWAVNGISKGIIKQFLGYVPIMVKSKLCNLYNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMVRPKWKTRGPGYTHYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQVLNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFALAKGECMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTNVSMNTDNLMRIFTMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPIDGAPHRSYSECYPVLLDGVMVGWVDKELAPGIADSLRHFKVLREKRIPPWTEVVLIPMTGKPSLYPGLFLFTTPCRLVRPVQNLELGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKIKQGDSSLVFGMKPGDPRILQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMYYKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKYNCTLCNRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA2, RNA polymerase I subunit 2, RPA135.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome.
Protein: AOAH_HUMAN
Sequence: MQSPWKILTVAPLFLLLSLQSSASPANDDQSRPSLSNGHTCVGCVLVVSVIEQLAQVHNSTVQASMERLCSYLPEKLFLKTTCYLVIDKFGSDIIKLLSADMNADVVCHTLEFCKQNTGQPLCHLYPLPKETWKFTLQKARQIVKKSPILKYSRSGSDICSLPVLAKICQKIKLAMEQSVPFKDVDSDKYSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVHQDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDSAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH
What is the function of this protein?
Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (PubMed:1883828, PubMed:8089145, PubMed:29343645).  By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses (By similarity).  In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria (By similarity).
What are the official names of this protein?
Acyloxyacyl hydrolase.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle. Note=Detected in urine.
Protein: RPOA_LEGPA
Sequence: MYTEINEMLTPKVLKVQAESPYKARIVLEPLERGFGHTLGNALRRILLSSMPGSAITEASIDGVLHEYSTIEGVQEDVVDLLLNLKSVAIKLTVGNEAQVTLNKEGPCQVTAGDIQLTHGQEIINPELVIANLNEKGKLNMTLKVERGIGFHNTDAFVRYHDDEIEKKTVGKLKIDNSFSPVKKVAYFVDSARVENRTDLDKLTIELETNGTIDAEEAIRISASILQRQLHAFVDMKFEESRADNKERNDFDPVLLRSVDDLELTVRSANCLKAENIHYIGDLVQRTESELLKTPNLGKKSLTEIKDVLASRSLSLGMKLENWPPASLGE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RS16_ACIBT
Sequence: MVVIRLARGGAKKRPFYQIVVTDSRNARDGRFIERIGFFNPTAQGQAEKLRLDADRFAHWVSQGAQPSERVASLAAQAKKATA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: FA13B_MOUSE
Sequence: MRKSSSPSLSNCNSDLASKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLLQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFGPDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEELPEEGVEKSAGMPEVLQLRMTENLLDSDSVTASTRIDAAAATTTNASDGNIKCSKPVAGTTADNEVMQQDFVFEDQKNNESVGILLEPCSDHGDSEDGCPERKEYLLCDSDKLPHLILDSSSKIRDLNANTELEVTEGQSVGVQGEAACIQIAQLDLKNVSDGDKWEEPFPAFKSWQEDCESGEAQLSPQAARMTHHPLGEDCPPVLSHRSLDFGQSQRFLHDPEALDFSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFAPQTRPRSNTLPKSFGSSLDHEDGESEGEPRVIQKEKTPSKEATLELITKRLKENRAERHLPEDIKKMTKDHLIEEKTSLQKSLLYYESQHGRPVTREERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVSLSSELGDILSTSVHTQSSLENLESDAEENQEKLARDLCLSSTRAASVPELLEQLWKARAEKKKLRKMLREFEEAFYQQNGRNAQKEDRVPVLEEYKEYKRIKAKLRLLEVLISKQDSSKSI
What are the official names of this protein?
Protein FAM13B.
What is the protein family that this protein belongs to?
Belongs to the FAM13 family.
Protein: TGT_SALTY
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPAFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRDRFDSLGNKNALFGIIQGSVYEDLRDISVKGLVEIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKSDTSPLDAECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTEFYQRQGRPVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: KAD2_PONAB
Sequence: MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.  Plays a key role in hematopoiesis.
What are the official names of this protein?
Adenylate kinase 2, mitochondrial, AK 2, ATP-AMP transphosphorylase 2, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: FOLD_BURP1
Sequence: MTATLIDGNALSKTLRAQAAERAAALAARGHRPGLAVILVGDNPASEVYVRNKIKACEDNGFFSLKDRYPATLSEPELLARIDELNRDPKIHGILVQLPLPAHIDSHKVIEAIAPEKDVDGFHVANAGALLTGKPLFRPCTPYGVMKMFEAYKIPLQGANAVVIGRSNIVGKPMALLLLEAGATVTICHSKTRELAAHTRAADIVVAAVGKRNVLTADMVKPGATVIDVGMNRNDEGKLCGDVDFAGVSQVAGHITPVPGGVGPMTITMLLVNTIEAAERAAAAA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: EHD3_MOUSE
Sequence: MFSWLGNDDRRKKDPEVFQTVSDGLKKLYKTKLLPLEEYYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDVEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNAVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDTKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEETQRPVQMVKGGAFEGTLQGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSELPAHLLPPSKRKVSE
What is the function of this protein?
ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis.  In vitro causes tubulation of endocytic membranes (By similarity).  Binding to phosphatidic acid induces its membrane tubulation activity (PubMed:26896729).  Plays a role in endocytic transport.  Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport.  Involved in the regulation of Golgi maintenance and morphology (By similarity).  Involved in the recycling of internalized D1 dopamine receptor (By similarity).  Plays a role in cardiac protein trafficking probably implicating ANK2.  Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction (PubMed:20489164, PubMed:24759929, PubMed:25825486).  In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function (PubMed:21408024).  Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance (By similarity).  Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing.  Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis; possibly sharing redundant functions with Ehd1 (PubMed:25686250).
What are the official names of this protein?
EH domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. EHD subfamily.
What are the subcellular locations of this protein?
Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Note=Localizes to the ciliary pocket from where the cilium protrudes (By similarity). Colocalizes with RAB8A and MYO5B to a cytoplasmic tubular network devoid of RAB11A (PubMed:17507647). Colocalizes with ANK2 in myocyte perinuclear region (PubMed:25825486). Colocalizes with BACE1 in tubulovesicular cytoplasmic membranes. Colocalizes with BACE1 and APP amyloid beta proteins in hippocampal mossy fiber terminals (PubMed:24373286).
Protein: ILVD_BUCCC
Sequence: MPKYRSFTTINGKNMAGARALWRATGVKDADFGKPIIAVVNSFTEFVPGHIHLRELGQLVSKEIEKSGGIAKEFNTIAIDDGIAMGHSGMLYSLPSRELIADSIEYMIQAHCVDAMVCISNCDKITPGMLLAALRLNIPSVFVSGGPMESGKILVNEKIIKIDLVDAMMHGANKNTSNKKLLNIEKSACPTCGSCSGMFTANSMNCLTEVLGLSFPGNGSLLATHIDRKNLFLKAGKIIVRNTKNYYENNDSSLLPRSIVTKENLKNAIILDISMGGSSNTVLHLLAMAYEANINFKMIDIDLLSRKVPHLCKISPSSSKYYMEDFHRAGGVFGILSELNKINLLNTSILNILRMSLEKTINKFDILKTKDKKIISFYSSGPGNKKTIYPFSQSFRWKKLDKDRISGCIRSKKYAYSKDGGLAVLTGNLAKNGSIIKTAAITNQSSKIFSGPAKVYESQEDAVYAILNNYIKSGDIIVIRYEGPKGGPGMQEMLYPTTYLKSMGLDKKCALITDGRFSGGTSGISIGHISPEAANKGLIALVYDNDIININIIDRSLKLKISSDEIRKRKEKEENRGIFAYTPKKRLRKISDSLKIYSMFATSADKGAVRNIHKINF
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RK22_DRANE
Sequence: MIKNKKKKSYTSVYALGQYISMSAHKARRVIDQIRGRSYEEALMILELMPYRGCYPIFKLVYSAAANASHNKGLKETNLVISKAEVNQGNTVKKLKPRARGRSYPIKRSTCHITIVLEDTSLYQQYDEYLMYFKKPGCSNENKNLTCYDTYSSGGLWDKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: INMT_RABIT
Sequence: MEGGFTGGDEYQKHFLPRDYLNTYYSFQSGPSPEAEMLKFNLECLHKTFGPGGLQGDTLIDIGSGPTIYQVLAACESFKDITLSDFTDRNREELAKWLKKEPGAYDWTPALKFACELEGNSGRWQEKAEKLRATVKRVLKCDANLSNPLTPVVLPPADCVLTLLAMECACCSLDAYRAALRNLASLLKPGGHLVTTVTLQLSSYMVGEREFSCVALEKEEVEQAVLDAGFDIEQLLYSPQSYSASTAPNRGVCFLVARKKPGS
What is the function of this protein?
Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity).  Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide.  Plays an important role in the detoxification of selenium compounds (By similarity).
What are the official names of this protein?
Indolethylamine N-methyltransferase, Indolamine N-methyltransferase, Aromatic alkylamine N-methyltransferase, Amine N-methyltransferase, Arylamine N-methyltransferase, Thioether S-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAC52_ARATH
Sequence: MGRESVAVVTAPPSATAPGTASVATSLAPGFRFHPTDEELVSYYLKRKVLGQPVRFDAIGEVDIYKHEPWDLAVFSRLKTRDQEWYFYSALDKKYGNGARMNRATNRGYWKATGKDREIRRDILLLGMKKTLVFHSGRAPDGLRTNWVMHEYRLVEYETEKNGNLVQDAYVLCRVFHKNNIGPPSGNRYAPFMEEEWADDEGALIPGIDVKLRLEPPPVANGNDQMDQEIQSASKSLININEPPRETAPLDIESDQQNHHENDLKPEEHNNNNNYDENEETLKREQMEEEERPPRPVCVLNKEAPLPLLQYKRRRQSESNNNSSRNTQDHCSSTTTTVDNTTTLISSSAAATNTAISALLEFSLMGISDKKEKPQQPLRPHKEPLPPQTPLASPEEKVNDLQKEIHQMSVERETFKLEMMSAEAMISILQSRIDALRQENEELKKNNANGQ
What is the function of this protein?
Transcriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968).  Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990).  Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019).  Together with NAC050 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990).  Regulates siRNA-dependent post-transcriptional gene silencing (PTGS) through SGS3 expression modulation (PubMed:28207953).  Required during pollen development (PubMed:19237690).
What are the official names of this protein?
NAC domain containing protein 52, ANAC052, NAC domain containing protein 51, ANAC051, Protein POLLEN DEVELOPMENT DEFECTIVE 1, Protein SUPPRESSOR OF GENE SILENCING 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CISD2_HUMAN
Sequence: MVLESVARIVKVQLPAYLKRLPVPESITGFARLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTGDNVGPLILKKKEV
What is the function of this protein?
Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum.  Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.  Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases.  Involved in life span control, probably via its function as regulator of autophagy.
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 2, Endoplasmic reticulum intermembrane small protein, MitoNEET-related 1 protein, Miner1, Nutrient-deprivation autophagy factor-1, NAF-1.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family. CISD2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Note=According to PubMed:20010695, it mainly localizes to the endoplasmic reticulum. However, experiments in mouse showed that it mainly localizes to the mitochondrion outer membrane.
Protein: MURC_SACD2
Sequence: MTEVTIHQVPEMRRIRRIHFVGIGGAGMSGIAEVLLNQGYEISGSDLRESDVTRRLAGMGVHVFIGHHATNVDGASVVVNSSAVESGNPELMEAREKRIPIVRRAEMLGELMRYRHGIAVAGTHGKTTTTSLISSILAAGKKDPTFIIGGLLNSAGSNAGLGESRYLVAEADESDASFLHLQPMVSVVTNIDADHMDTYEGDFSKLKQTFIDFLHNLPFYGLAVVCGDDPIVTELIPAISRSVVTYGFNEDSDYRAFDVRQDGSKLRFKVARPEGLATLELFLNMPGKHNVLNATAAVAVASEEKVDDDAIQNGLANFMGVGRRFEIYGEFEVGAGPTAMLVDDYGHHPREVAATIAAVRDGWPDRRLVMVYQPHRYSRTRDLYEDFVEVLSTVDQLVLLEVYSAGEDPIPGADSRHLSRTIRTRGVVDPIFVEGVEGVPAVIKDIVQPGDIIITQGAGNVGTLAKELAKRNLG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_SHISS
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ANKL1_HUMAN
Sequence: MCSEARLARRLRDALREEEPWAVEELLRCGADPNLVLEDGAAAVHLAAGARHPRGLRCLGALLRQGGDPNARSVEALTPLHVAAAWGCRRGLELLLSQGADPALRDQDGLRPLDLALQQGHLECARVLQDLDTRTRTRTRIGAETQEPEPAPGTPGLSGPTDETLDSIALQKQPCRGDNRDIGLEADPGPPSLPVPLETVDKHGSSASPPGHWDYSSDASFVTAVEVSGAEDPASDTPPWAGSLPPTRQGLLHVVHANQRVPRSQGTEAELNARLQALTLTPPNAAGFQSSPSSMPLLDRSPAHSPPRTPTPGASDCHCLWEHQTSIDSDMATLWLTEDEASSTGGREPVGPCRHLPVSTVSDLELLKGLRALGENPHPITPFTRQLYHQQLEEAQIAPGPEFSGHSLELAAALRTGCIPDVQADEDALAQQFEQPDPARRWREGVVKSSFTYLLLDPRETQDLPARAFSLTPAERLQTFIRAIFYVGKGTRARPYVHLWEALGHHGRSRKQPHQACPKVRQILDIWASGCGVVSLHCFQHVVAVEAYTREACIVEALGIQTLTNQKQGHCYGVVAGWPPARRRRLGVHLLHRALLVFLAEGERQLHPQDIQARG
What is the function of this protein?
Endonuclease that probably plays a role in the DNA damage response and DNA repair.
What are the official names of this protein?
Ankyrin repeat and LEM domain-containing protein 1, Ankyrin repeat domain-containing protein 41, LEM-domain containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=At the steady state, localizes predominantly in the cytoplasm.
Protein: PGKE_TRYBB
Sequence: MSLKERKSINECDLKGKKVLIRVDFNVPLDDGNITNDYRIRSALPAVQKVLTEGGSCVLMSHLGRPKGVSMAEGKELRSTGGIPGFEQKATLKPVAKALSELLSRPVTFAPDCLNAADVVSKMSPGDVVLLENVRFYKEEGSKSTEEREAMAKILASYGDVYISDAFGTAHRDSATMTGIPKILGHGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQRIDYLLIGGAMAYTFLKAQGYSIGISMCEESKLEFARSLLKKAEDRKVQVILPIDHVCHTEFKAVDSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIAKAMGRGTHEHGLMSIIGGGESAGAAELCGEAARISHVSTGGGASLELLEGKTLPGVTVLDEKE
What are the official names of this protein?
Phosphoglycerate kinase, cytosolic, PGK B allele 4, Phosphoglycerate kinase B.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_BACTN
Sequence: MLEKEEIVSPNLEELKSHYHSIITLLGEDAGREGLLKTPERVAKAMLSLTKGYHMDPHEVLRSAKFQEEYSQMVIVKDIDFFSLCEHHMLPFYGKAHVAYIPNGYITGLSKIARVVDIFSHRLQVQERMTLQIKDCIQETLNPLGVMVVVEAKHMCMQMRGVEKQNSITTTSDFTGAFNQAKTREEFMNLIQHGRV
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CAND1_DROME
Sequence: MASHQYHQIANLLEKMTSTDKDFRFMATNDLMTELQKDSIILDDESEKKVVRMVLKLLEDKNGEVQNLAVKCLGPLVNKVKEIQVETIVDSLCANMMSNTEQLRDISSIGLKTVIAELPQSSNSLAPNVCQRITGKLSTAIEKEDVSVKLESLDILADLLSRFGEFLVPFHSTILKALMPQLASSRQAVRKRTIVALSFLLIQANSNAYNGVIDHLLDGLENPPNPAAIRTYIQCLASICRQAGHRLCNHIDRSMLLLSQYSQRDDDELREFCLQACEAFVMRCPDAINPHIPMILELCLNYITYDPNYNYETDDGDTGNAMDTEDDEYVDSEEYSDDDDMSWKVRRAAAKCLEVLISTRQELVEDFYRSLSPALIARFKEREENVKSDIFHAYVALLKNTRLTDDVANDHDSMDQVSGPTSLLIEQLPLIVKAIQPLMREKSMKTRQDCFLLLRELLNSLPGALGPYLDSIVPGISYSLNDKSSTSNMKIESLGFLYSLLQGHPPHVFHPHIPLLVPLVVTSVFDPFYKIATEALLVLQQLVKVIRPLEPNAAKSDFDAPSFVGQVYSCTLQKLKVTDVDQEVKERAIACMGQIIANMGDMLQNELAVCLPIFMERLKNEVTRLSSVKALTLIAASSLRIDLTPILHDVLPALGTFLRKNHRALKLHSLDLINKIVINYSSNFEANLLQTAIVEIPPLISDSDLHVAQYSLTLLSTVARRQPQALVGIHEQFLRSVLILVRSPLLQGSALNCTLELFQALVQTQLSGLDYHSLVSKLMAPVLGGNGDVKSRATAGAPSEVVQLHKQAYHSSAKCIAALTQQCPQVATPLATKLITDLQKRNDTEIIFCLLTIGEIGRHFDLSSIQVLPQTIIECFGATSEDVKAAASHALGAVSVGSLQTYLPLILHEIEVQPKRQYLLLHSLKEVISSLSVSPSGLAQLLPSVPSIWDQLFKHCECSEEGSRNVVAECLGKLVLVNPDELLPQLQQALRSESATMRTVVVSSVKFTISDQPQPIDVLLKQNIGEFLFALRDPEPQVRRVALVAFNSAVHNKPSLVRDLLPTLLPWLYSETKVKSELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLEQGLDRVDVMQFLDHVQAGLCDHYDIKMLTYLMTARLAILCPDKVLLRLDQFIQQLRDTCTHKVKANSVKQEYEKQDELKRSALRAVSALSQIPKANKNQQLVDFLKSIKETPELNKIFEYIQKDSITGSSDIIVMDQS
What is the function of this protein?
Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes.  Acts as a F-box protein exchange factor.  Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes (Probable).
What are the official names of this protein?
Cullin-associated NEDD8-dissociated protein 1, Cullin-associated and neddylation-dissociated protein 1.
What is the protein family that this protein belongs to?
Belongs to the CAND family.