PharMolix/UniProtQA huggingface dataset:
Protein: TFDR_CUPPJ
Sequence: MEFRQLRYFVAAAEEGNVGAAARRLHISQPPVTRQIHALEQHLGVLLFERSARGVQLTPAGAAFLEDARRMLELGRTSVDRSRAASRGEIGQLDIGYLGTAIYQTVPALLHAFTQAVPGATLSLALMPKVRQIEALRAGTIHLGVGRFYPQEPGITVEHLHYERLYIAAGSSIARQLRQDPTLLRLKSESLVLFPKEGRPSFADEVIALMRRAGVEPRVTAIVEDVNAALGLVAAGAGVTLVPASVAAIRRPFVRTMEMADASDKVPVSLTYLTDSRVPVLRAFLDVARRGKGQK
What is the function of this protein?
Involved in the regulation of 3-chlorocatechol degradation.  Transcriptional regulator of tfdB expression.  Acts as a repressor in the absence of its effector (either 2-cis-chlorodiene lactone or chloromaleylacetate) but acts as an activator when its effector is present.
What are the official names of this protein?
HTH-type transcriptional regulator TdfR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_SHEWM
Sequence: MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTAIYVATDDDRIKEAVEAFGGKVVMTDPQAASGTDRIEDAITQLGLKDDDLIVNLQGDQPLIDPISIEQVITLFERHPGEFSMATLGVEITEKAELDDPKHVKMVFDNNFNALYFSRARIPFGRDTNDYPVYKHLGIYAYTRSFISTFAKLPLGRLEDLEKLEQLRALEHGHKIKVAISAFDSPEVDTPEDIRICEARLAVD
What is the function of this protein?
Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
What are the official names of this protein?
8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase, CMP-8-amino-3,8-dideoxy-manno-octulosonate synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_RHIL3
Sequence: MNIFRLFNKQRTAPAARERLQVLLAHERSSAGSDLVTLLREEILAVIAKHVQLDHDKVQVTIDRNEYVSTLEIDVEIPLNAAVQAA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: E1127_IXORI
Sequence: MEAKTFAFLEIAMFIALGIQTFVAVTDAAGKDDEHFSVDYCGMNCTQQEDGSWTACSGRNGECRCYHESGKRSGLCLSTTYIDFSEYGNLSDSDIAAASPRLSMKESH
What is the function of this protein?
Salivary chemokine-binding protein which binds to host chemokines CXCL1, CXCL2, CXCL3, CXCL5 and CXCL8.
What are the official names of this protein?
Evasin P1127.
What are the subcellular locations of this protein?
Secreted.
Protein: MIA40_ORYSJ
Sequence: MGQGLSQPAQAVEEPSPPAVEAAPSSSPSPAPAPSSLEALAAEAMSFDEDGNESIDVKVQKALDCPCVAELKNGPCGSQFVDAFSCFLKSTEEEKGSDCVKPFIALQDCIKINPEAFSKEILEEEENDEEAEKSNLKVRAPAWSRESKPKL
What is the function of this protein?
Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space.
What are the official names of this protein?
Mitochondrial intermembrane space import and assembly protein 40 homolog, OsMIA40.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Peroxisome matrix.
Protein: IKP1_PHYSA
Sequence: VIEPKCYKYEGKKCPPDINPVCGTDKRTYYNECALCVFIRQSTKKADKAIKIKKWGKC
What is the function of this protein?
Has antibacterial activity against Gram-negative bacterium E. coli ATCC 11229.  Shows hemagglutinating activity.  Inhibits prolyl endopeptidase, but not trypsin, chymotrypsin, V8 protease and proteinase K.  May have a role in mucosal defense against microbes by interacting directly with their membranes.
What are the official names of this protein?
Proteinase inhibitor PSKP-1.
What are the subcellular locations of this protein?
Secreted.
Protein: PT1_STAEQ
Sequence: MSKLIKGIAASDGVAIAKAYLIVEPDLSYDSNEKVTDIESEVEKFNDAIEASKIELTKIRNNAEAQLGADKAAIFDAHLLVLDDPELIQPIQDKIRNDKVNAATGLDEVTTQFISIFESMDNEYMKERAADIRDVSKRVLAHILGVDLPNPSLINESAVIVGNDLTPSDTAQLNKEFVQGFVTNIGGRTSHSAIMSRSLEIAAVVGTKSITEEVKQGDMIIVDGMSGDVIIDPTEDELIAYQNKRERFFEDKKELQKLRDADTVTVDGVHAELAANIGTPDDLSGVIDNGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKKVLETMDGKRVVVRTLDIGGDKELPYLDLPKEMNPFLGYRAIRLCLAQPEIFRPQLRALLRASVYGKLNIMFPMVATIKEFRDAKSMLLEEKENLLREGYEVSDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDQTAVPLLLGLGLDEFSMSATSILKARRQINGLSKNEMAELANRAVECSTQEEVVDLVNQLAK
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_CLOPS
Sequence: MARKAMIEKWKKEPKYKTRAYTRCRLCGRPHSVLKKFGICRICFRELAYKGEIPGCRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: Y2509_BACVZ
Sequence: MIIRDLPLKLRDFPEKEKPRERLLHFGAEHLSNNELLAILLRTGTKHESVMNLAHRLLRTFDGLRLLKGASAQELSSIPGIGTVKAVQILAAIELGSRIHKTSAGEHCVIRSPEDGAKYVMEDMRFLSQEHFVCLYLNTKNQVIHKRTVFIGSLNSSIVHPREVFKEAFKRSAASFICVHNHPSGDPTPSREDIEVTRRLFECGNLIGIELLDHLVIGDKKFVSLKEKGYL
What are the official names of this protein?
UPF0758 protein RBAM_025090.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: ARGJ_LEPIN
Sequence: MHMPKGFLSFGINIGIKDDTKDFGVIYSEIPCKATAVFTKNNFPGAPVIVGKEHVRSGVLQAIVINSKNSNVATGEKGIQNSREICKIIGESLGIKETLVLPSSTGVIGVPLKMEIILPACKKAKSLLKPGNLEEVAEAIMTTDTRKKISSRNIKTKSGQGTIYGIAKGAGMIEPNMATMLCYILSDVSLPEGTDLYSILKSSVDQSFNCLTIDSDTSTSDTVALLCNGLSGESSVQDFSKALTEICIDLTKLIATDGEGATKLIELTISGAKSEAQARKIGKSILNSPLVKTAIYGGDPNWGRLIMAVGKVFDEPIPFEGLQIYFGTLPVKEANPETLKKLSEYLKNNTEISLNVVLNVGTISMKFWGCDFTEKYIEENAYYTT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_BURCM
Sequence: MANDYLFTSESVSEGHPDKVADQISDAILDAILEQDKYSRVAAETLCNTGLVVLAGEITTTANIDYIQIARDTIKRIGYDNTDYGIDYKGCAVLVAYDKQSPDIAQGVDRAHDDNLDQGAGDQGLMFGYACDETPELMPLPIYLSHRLVERQASLRRDGRLPWLRPDAKSQVTVRYVDGRPDSIDTVVLSTQHAPDIELPALREAVIEEIIKPTLPADLIKGDIKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALIQVSYAIGVAEPTSVMVNTFGTGRVSDAVITKLVREHFDLRPKGIIKMLDLLRPIYEKTAAYGHFGREEPEFSWEATDKALVLAEAAGVEPTARVA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTH4_RHOER
Sequence: MYRVTIVYNHPADPAAFDEHYSSKHVPLVQQIPSVKRFAAGKCDSLDGNPPSAYALAQLYFESKAEAGQAFASPEGQNAAADVANFASGGVTMLFTDEETVLP
What are the official names of this protein?
Uncharacterized 11.0 kDa protein in thcB-thcC intergenic region, ORF4.
Protein: TPIS_XANOM
Sequence: MRRKIVAGNWKLHGSRAFATELVAKLAAHMPLEGIDVVILPPLPYLGDLIEDFEAHHLSFGAQDVSSNEKGAYTGEVSASMLVDVGAGYGLVGHSERRQYHQESSELVARKFAAAIHAGLTPVLCVGESLEQREAGQTEAILRAQLEPVLALVGSAGFAGAVLAYEPIWAIGTGCTATPEQAQAVHAFLRGEVAKADARIADSLPILYGGSVKPDNAGELFAQPDVDGGLVGGASLVAEDFLAIARAAAAC
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_PHOPR
Sequence: MTIILGIDPGSRITGYGVIRQVGRNLEYLGSGCIRTSAEDIPGRLKQIYAGVSEVITQFQPDTFAIEEVFMGKNASSALKLGQARGSAIVAAVNADLPVSEYAARLIKQAVVGTGAADKAQVQHMVCSVLKLPGKPQADAADALAVAICHAHTHKTLIAMSGKASSARRGRYR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RS3_CHLP8
Sequence: MGQKVNPTGFRLGIIKDWTSRWYDDGPVIAEKIKQDQVIRNYISARLKKEKAGVSKVVIERTTKHIKINIYAARPGAVVGRKGEEINNLSQELTRITGREVKIDVIEVIKPEIEAQLIGENIAYQLENRVSFRRAMKQAIQQAMRAGAEGIRIRCAGRLGGVEIARSEQYKEGKIPLHTLRANVDYASVTAHTIAGAIGIKVWVYKGEVLVQRLDAIEEEEMKKMQERRNDSRGRGRGDGRGAKRRRRPAAKKA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: INO80_YEAS7
Sequence: MSLAVLLNKEDKDISDFSKTTAGKSAKKNSRERVADVAPTRVLDKKQAYLSQLNSEFNRIKKRDSIEQLYQDWKFINLQEFELISEWNQQSKDWQFDNTNDSQDLHFKKLYRDMSMINKEWAEYQSFKNANLSDIINEKDADEDEEDDEDELEDGEEDMEEDEASTGRHTNGKSMRGNGIQKSRKKDAAAAAAVGKAIKDDQTHADTVVTVNGDENEDGNNDEDNDNDNENNNDNDNDNDNDNDNDNENENDNDNDNDDEEENGEEDEEEEEIEDLDEEDFAAFEEQDDNDDEDFNPDVEKRRKRSSSSSSSTKLSMNSLSLITSKKINKNITINSDRPKIVRELIKMCNKNKHQKIKKRRFTNCIVTDYNPIDSKLNIKITLKQYHVKRLKKLINDAKREREREEALKNNVGLDGNDLDNDEDGSESHKRRKLNNNTANGADDANKRKFNTRHGLPTYGMKMNAKEARAIQRHYDNTYTTIWKDMARKDSTKMSRLVQQIQSIRSTNFRKTSSLCAREAKKWQSKNFKQIKDFQTRARRGIREMSNFWKKNEREERDLKKKIEKEAMEQAKKEEEEKESKRQAKKLNFLLTQTELYSHFIGRKIKTNELEGNNVSNNDSESQKNIDISALAPNKNDFHAIDFDNENDEQLRLRAAENASNALAETRAKAKQFDDHANAHGEEEEEDELNFQNPTSLGEITIEQPKILACTLKEYQLKGLNWLANLYDQGINGILADEMGLGKTVQSISVLAHLAENHNIWGPFLVVTPASTLHNWVNEISKFLPQFKILPYWGNANDRKVLRKFWDRKNLRYSKNAPFHVMVTSYQMVVTDANYLQKMKWQYMILDEAQAIKSSQSSRWKNLLSFHCRNRLLLTGTPIQNSMQELWALLHFIMPSLFDSHDEFNEWFSKDIESHAEANTKLNQQQLRRLHMILKPFMLRRVKKNVQSELGDKIEIDVLCDLTQRQAKLYQVLKSQISTNYDAIENAATNDSTSNSASNSGSDQNLINAVMQFRKVCNHPDLFERADVDSPFSFTTFGKTTSMLTASVANNNSSVISNSNMNLSSMSSNNISNGKFTDLIYSSRNPIKYSLPRLIYEDLILPNYNNDVDIANKLKNVKFNIFNPSINYELCLFLSKLTGEPSLNEFFRVSNTPLLKRVIERTNGPKNTDSLSFKTITQELLEVTRNAPSEGVMASLLNVKKHAYEREYLNCIQRGYHPNVSAPPVTIEVLGSSHVTNSINNELFDPLISQALSDIPAITQYNMHVKKGIPVEDFPKTGLFPEPLNKNFSSNISTPSMDRFITESAKLRKLDELLVKLKSEGHRVLIYFQMTKMMDLMEEYLTYRQYNHIRLDGSSKLEDRRDLVHDWQTNPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLVRGTIEERMRDRAKQKEQVQQVVMEGKTQEKNIKTIEVGENDSEVTREGSKSISQDGIKEAASALA
What is the function of this protein?
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.  Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates.  The INO80 complex is involved in DNA repair by associating with 'Ser-129' phosphorylated H2A histones as a response to DNA damage.
What are the official names of this protein?
Chromatin-remodeling ATPase INO80, Inositol-requiring protein 80.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL29_STRAW
Sequence: MSAGTKASELRELGDEELLAKLREAKEELFNLRFQAATGQLENHGRLKAVRKDIARIYTLMRERELGIETVESA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: UBP42_RAT
Sequence: MTIVDKTEPSDPSTCQNQPGSSEAVSPEDMDTGSASWGAVSSISDVSNHTLSLGPVPGAVVYNNSSVPEKSKPSPPKDQVLGDGIAPPQKVLFPSEKICLKWQQSHRVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCHAEGFCMMCTMQTHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYMSQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLNQQAYVLFYIRSHDVKNGGETTHPAHSPGQSSPRPGISQRVVNSKQAAPGFIGPQLPPHVMKNTPHLNGTTPVKDTPSSSVSSPNGNTSVNRASPATASTSVQNWSVNRPSVIPEHPKKQKITISIHNKLPVRQGQAQLNNNLHGPCLEAPSKAAPSSTITNPSAIQSTSNAPTTSVSPSESCPKPMVNGKAKVGSSVLVPYGAESSEESDEESKGLAKENGVDMMTSTQSSRPETADEDGEASPHELQESVMLNGANSADSDSRESSLAFDSASCQVQPDLHTENLFNKLNGLPGKVTPAPLQSVPEDKILETFKLTNQAKGPAVEESWTTTGGSSPRASVSQPEPITDETSPLEIPEAVTNGSMKTPSTTSPLEPTISCTKEDSSVVVVSAEPMEVLPSVPALCNSTGTTLGDAPVPESCDPGDLTANPSQPSQAVKGDPAENSENSTLAEVVERLSPAPSVLTGDGCEQKLFLYLSTEGSEEAEDSSRSSAVSADTVPPQPDRTTSSCAGAAEQAAGDRGDGGSVGPKAQEPSPAKEKMNSLRKVDRGHYRSRRDRSSSGEHVRDSRARPEDHHHKKRRCYSRERPKQERHPANTYCNGGQHLGHGDRASPERRSLSRYSHHHSRVRSGLEQDWSRYHHSENEPAWARERFYPDKMRWDKCRYYHDRYTTTLYTAREAAREWRPLHGREHERLVQSGRPHKDSYWGRKGWDLQSRGKERPHFHSPREAPGLAVPLERHLQEKAALSVQDSSHSLPERFHEHESVKLRKRRYETLDNNDDHPEKKVHKSLEKDALEEPRAKKHKKSKKKKKSKDKHRARDSRHQQESDFSGAYSDADLHRHRKKKKKKKRHSRKSEDFIKDVEMHLPKLSSYEAVGHFRRTEGTFLLADGLPVEDSGPFREKTKHLRMESRPDRCHLSEYGQGN
What is the function of this protein?
Deubiquitinating enzyme which may play an important role during spermatogenesis.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 42, Deubiquitinating enzyme 42, Ubiquitin thioesterase 42, Ubiquitin-specific-processing protease 42.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: NCAP_BCCV
Sequence: MSNLKEVQDNITTHEQQLVAARQKLKDAERTVGVDPDDVNKSTLQNRRAAVSALEAKIGELKRQLADLVAAQKLATKSVDPTGIEPDDHLKEKSSLRYGNVLDVNSIDLEEPSGQTADWKAIGTYILSFVLPIVLKALYMLSTRGRQTVKENKGTRIRFKDDSSYEDVNGIRKPKHLYVSLPTAQSTMKADEITPGRFRTIVCGLFPAQIKARNIISPVMGVIGFSFFVKDWVDKIEDFLRAECPFLPKPRAQAESFLSTNGAYFMNRQTQVEESKVQDILDLIDTAESGGATLFDNIASPQSAWIFACAPDRCPPTALYVAGVPELGAFFSILQDMRNTIMASKSVGTAEEKLKKKSAFYQSYLRRTQSMGIQLDQKIIILYMINWGKEAVNHFHLGDDMDPELRQLAQALVDTKVKEISNQEPLKI
What is the function of this protein?
Encapsidates the genome protecting it from nucleases (Probable).  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication (Probable).  The nucleocapsid has a left-handed helical structure (By similarity).  As a trimer, specifically binds and acts as a chaperone to unwind the panhandle structure formed by the viral RNA (vRNA) termini (By similarity).  Involved in the transcription and replication initiation of vRNA by mediating primer annealing (By similarity).  Plays a role in cap snatching by sequestering capped RNAs in P bodies for use by the viral RdRp during transcription initiation (By similarity).  Substitutes for the cellular cap-binding complex (eIF4F) to preferentially facilitate the translation of capped mRNAs (By similarity).  Initiates the translation by specifically binding to the cap and 40S ribosomal subunit (By similarity).  Prevents the viral glycoprotein N (Gn) from autophagy-dependent breakdown maybe by blocking autophagosome formation (By similarity).  Inhibits host EIF2AK2/PKR dimerization to prevent PKR-induced translational shutdown in cells and thus the activation of the antiviral state (By similarity).  Also displays sequence-unspecific DNA endonuclease activity (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the hantavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host Golgi apparatus, host cis-Golgi network. Note=Internal protein of virus particle.
Protein: NUOCD_ECO81
Sequence: MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: H14H1_CYRHA
Sequence: MKVVLLVCLVWMMAMMELVSCECWSQADCSDGHCCAGSSFSENCRPYGGDGEQCEPRNKYEVYSTGCPCEENLMCSVINRCQSA
What are the official names of this protein?
U8-theraphotoxin-Hhn1g, U8-TRTX-Hhn1g, Hainantoxin-XIV-8, HNTX-XIV-8.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRYAA_LOXAF
Sequence: MDVTIQHPWFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDQFVILLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQSGMDASHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: HIPA_SHEON
Sequence: MSTAKTLTLEMHLGDLMIGELSFDATADTFAVHYTKDWQQSGFPLSPTIPLDGTGTSNQISMFLVNLLPENKGLDYLIESLGVSKGNTFALIRAIGLDTAGAIAFVPKGALLPETQLRPIKAEEVIQRIEDPTMWPMEIWDGKPRLSVAGVQPKLNLFYNGKEFAFAEGTLSSTHIVKFEKYHHLVINEFITMRLAKVLGMNVANVDIVHFGRYKALCVERFDRRNIPGEQRVLRRHIVDSCQALGFSVSKKYERNFGTGRDVKDIREGVSFNRLFSLAAKCRNPVAAKQDMLQWALFNLLTGNADAHGKNYSFFMTPSGMEPTPWYDLVSVDMYEDFEQQLAMAIDDEFDPNSIYAYQLAAFMDGLGLPRNLLISNLTRIARRIPQAIAEVILMLPPLDEDEASFVAHYKTQLLARCERYLGFVDEVRDVEV
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system; overexpression in wild-type temporarily inhibits cell growth, overexpression in a hipAB deletion leads to acute growth inhibition.  The toxic effect of HipA is neutralized by its cognate antitoxin HipB.  In the ternary phosphoserine-HipA-HipB-DNA complex the DNA is bent about 125 degrees; all HipA in the crystallized ternary complex is phosphorylated.  In E. coli phosphorylation of HipA is thought to release HipB from the HipA-HipB-DNA complex, suggesting the complex functions differently in the 2 bacteria (PubMed:25056321).  Phosphorylates Glu-tRNA-ligase (GltX, on 'Ser-239') in vivo, with HipB probably acts as a corepressor for transcription of the hipBA promoter (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase toxin HipA, Ser/Thr-protein kinase HipA, Toxin HipA.
What is the protein family that this protein belongs to?
Belongs to the HipA Ser/Thr kinase family.
Protein: LEUC_CLOD6
Sequence: MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIREFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGIEHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGAIKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMAIEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAKLKETVAFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIFPGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVGRMGHVDSEVYLASPAVAAASAITGKISKPSEII
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: RL25_XANAC
Sequence: MAKTHEIKVERRADEGKGASRRLRHAGVIPAIVYGGELEPVSIQLNHEQIWLAQQNEWFYSSILDLNLNGDVQQVLLRDMQRHPFKQLIMHIDFQRVSANEKLSAAVPLHFINEASSPAGKSSEVVVTHELNEVQVVCLPKDLPEFIEVDLGALEVGNVIHLSEIKLPAGVEIPELKLGKEHDVAVVAAKHVRIEEDDAAGEEGSEGAETK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: SYS_THIDA
Sequence: MLDIQLLRKDAALVAERLAARGFAFDAARFDALEAERKTIQTRTQDAQSRRNTLSKQIGMLKGKGEDTTAVMAEVGGLGDELKQLETRLSELQAELNDFLMGIPNLPHESVAPGKDETANVEVSRWGTPRQFDFAVRDHVDLGEGLGQLDFAAAVKITGSRFSVMRGGLARLHRALAQFMLDLHTTEHGYTEVYVPYVVNAESMRGTGQLPKFEEDLFHVPRSDADRLYLIPTAEVPVTNLVRDEIVAAEALPLKFVAHTPCFRSEAGSYGRDTRGMIRQHQFDKVELVQMVRPEDSYAALEGLAAHAETVLQRLGLPYRKMALCSGDMGFSAAKTYDLEVWLPAQNTYREISSCSNFEAFQARRMQARFREGQGKPELLHTLNGSGLAVGRTLVAILENYQNADGSITVPEALRPWMGGVERLTPA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.