PharMolix/UniProtQA huggingface dataset:
Protein: POED2_ARATH
Sequence: MVELEIVWLVRGAWITVWIVSILPLVIASIPTSKLNSFRELVLSFAGRGKILHPSSQKFTIPQKCFAHFYVIGVVWTTLLLAATWMYACKMAPLSSEEFQLSDIASRLAGGSDVFSVHKSNMTPVEHRFKVWRAVFLLLLMEIHVLRRLIESFYVFKYSPSARMHILGYFAGLFFYVTAPLSLCSNIAPEVAGFVGNQVAEFIANGKSHTSAPEFNLLSSISPLMKLGSLQWIGGAIFLWGWIHQRRCHAILGSLRENPSQAKEYIIPYGDWFGMVSSPHFLAEIVLYAGLLIASGGTDITIWLLFGFVAANLTYAAGETHRWYLRKFENYPANRHAIFPYVY
What is the function of this protein?
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol.  Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.  Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.  Involved in the regulation of plant growth and reproductive processes.
What are the official names of this protein?
Polyprenol reductase 2.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: O5H15_HUMAN
Sequence: MEEENATLLTEFVLTGFLYQPQWKIPLFLAFLVIYLITIMGNLGLIAVIWKDPHLHIPMYLLLGNLAFVDAWISSTVTPKMLNNFLAKSKMISLSECKIQFFSIAIGVTTECFLLATMAYDRYVAICKPLLYPAIMTNGLCIRLLILSYIAGILHALIHEGFLFRLTFCNSNIVHHIYCDTIPLSKISCTDSSINFLMVFIFSGSIQVFSIVTILISYTFVLFTVLEKKSDKGVRKAFSTCGAHLFSVCLYYGPLLLMYVGPASPQADGQNMVEPLFYTVIIPLLNPIIYSLRNKQVIVSFIKMLKRNVKVSY
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5H15.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREG_LYSSC
Sequence: MKPIRIGIGGPVGSGKTSLVDQLTRVMHEHYHVAVITNDIYTREDAQYLITNGVLAEERIIGVETGGCPHTAIREDASMNFAAIDDLTKRFKNLDIIFIESGGDNLSATFSPELVHGYIYVIDVAEGQDIPRKGGPALTRSDLLLINKTSLAPHVGVDLDIMDQDVKKMRGGRPYIFADVRSQTNVDKVVEWIQHHMLLEGAEAVDNHG
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHAS_CORML
Sequence: MTTIAVVGATGQVGQVMRTLLEERNFPADTVRFFASPRSAGRKIEFRGTEIEVEDITQATEESLKDIDVALFSAGGTASKQYAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPSDKDSLVKGIIANPNCTTMAAMPVLKPLHDAAGLVKLHVSSYQAVSGSGLAGVETLAKQVAAVGDHNVEFVHDGQAADAGDVGPYVSPIAYNVLPFAGNLVDDGTFETDEEQKLRNESRKILGLPDLKVSGTCVRVPVFTGHTLTIHAEFDKAITVEQAQEILGAASGVKLVDVPTPLAAAGIDESLVGRIRQDSTVDDNRGLVLVVSGDNLRKGAALNTIQIAELLVK
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: DAAF8_MACFA
Sequence: MASNDEGMAPSLGSPWASQTGPWDAILKAVKDQLPSLDSDSSLSDYGEEELSIFQRNQTALIPDLSEELAEDPADGDKSRTWAAAAEESLPEVCGTQKSVRLCVCNPALVPAELATEPGNRRNTRTKDASSQEGRDPGRPVETSGEVSAFLGMAEETPRWLGSDLGSLSFNTKGSQGPPWDPQAKASLSRHEGDPKAEPASQESVNRRALRQERRKMIEKDILQKVTRDACGPASSDQGGVKEAPCHAVESAARSKMPLAEPPEGPPVLSLQQLEAWDLDYILQSLAGQEDNQGNRGPGTVWWAADRRQVQDRTVPSADDRLMEQLALLCTMQSRASACAWKVPADTPQDTEEAGAGSRCSSRKPGSEAGPGPQLAQGMRLNTEPPTIFIDLRQTVPPDHLSPARSRGSSHSSSDSEEEEEEVEMAALGDAEGASPSSLGLRSCTGKSQLLQQLRAFRKGIAQPKLPANKGPGGERAQAPEDTAASGTVRKQHMKLCAKGQSAQARLPRGRPRALGDAPEPGAAREALMPPLDQL
What is the function of this protein?
In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme.  Interacts with outer dynein arm (ODA) subunits.
What are the official names of this protein?
Dynein axonemal assembly factor 8, Dynein axonemal-associated protein 1, Uncharacterized protein C16orf71 homolog.
What are the subcellular locations of this protein?
Dynein axonemal particle.
Protein: PSTS_STAAC
Sequence: MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSSTVAPIVEKLNEKWAQDHSDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQDKNIKYKEFKIAQDGVTVAVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKINAVSPNSSHGTYDFFENEVMNKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQNKDKLKEVKIKDENGKATEPTKKTIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVLEDKGKAAEEAGYVAAPEKTYKSQLDDLKAFIDKNQKSDDKKSDDKKSEDKK
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS, PBP.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYC_ACET2
Sequence: MRLYNTLTRKKEEFHPIDEKEVKMYSCGPTVYNYFHIGNARPFIIFDTLRRYLEYKGYNVKFVQNFTDIDDKMIKRANEEGITVKELADKFINEYFVDAKGLGIKEATVHPRATENIDAIIEMIKKLEEKGFAYNVDGDVYFSARKFTEYGKLSHQSLEDLELGARIDVDERKKDPMDFALWKAQKPGEPAWDSPWGKGRPGWHIECSAMANKYLGETIDIHSGGQDLVFPHHENEIAQSEAANGKPFARFWLHNGFINVDGEKMAKSKGNFFTVRDIAKTFDYEVIRFFMLSAHYRSPINFSAELLEQAKNGLERIYNCLDNLEYLKEHAQAEKITDSERELQNRLLGIKAKFIEAMDDDINTADAIAAIFDIVKEVNTNINATSNSSKEIIDFSLSLIKELGGVLGIAQKSRQKVLDKEIEELIERRQKARKEKDWKTADEIRDKLKEMGIILEDTPQGVKWTIQR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YUZE_BACSU
Sequence: MKAVTYDTDSELAYIYVLPPKKNRNVRTEELRVNDCLLLDISQDGKIAGFECFGEAAHLCAPFAGKSRLYVKDSDGYHFRVCQHASVRSCYTVYRVTFCFSDGDYQEFAGFDLDGTMYHSAFLQRLTEK
What are the official names of this protein?
Uncharacterized protein YuzE.
Protein: AN321_CAEEL
Sequence: MPSMAEIYVKELRERDPATVDTLFLDNAEDGQIGGLTDQLINLEMLSMVKCGLTTLAGFPTLPALTYLDISDNQLGDNASFDVLVKNAPDLKKITLASNKLSLDNLRCLKVLPNLFELDLSNNPSLGLLEDYREKMFEMIPSLKILDGCDVDGEEVEEEFAGEGGEDSEEGSGDEDGPGLSYLEKSQFSDDETDDYAPEGGDAEPRGTKRGASDNGEEPDNKKAAGDDE
What are the official names of this protein?
Acidic leucine-rich nuclear phosphoprotein 32-related protein 1, ANP32/acidic nuclear phosphoprotein-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the ANP32 family.
Protein: MSBA_PSEF5
Sequence: MTDSSPDASPSSLKIYFRLLGYVRPYIGLFLISIVGFLIFASTQPMLGYILKYFVDGLSNPQAVLFPGVPYLRDMQLLQAVPLLIVLIAAWQGLGSYLGNYFLAKVSLGLVHDLRVQLFNNLLTLPNRYFDKHNSGHLISRITFNVTMVTGAATDAIKVVIREGMTVIFLFGSLLWMNWRLTLVMIAILPLIAVMVRTASKKFRKQSKKIQVAMGDVTHVASETIQGYRVVRSFGGETYEQQRFLAASQGNTDKQLRMTRTGAIYTPLLQLVIYSAMAVLMFLVLYLRGDASAGEMVAYITMAGLLPKPIRQLSEVSSTIQKGVAGAESIFEQLDVEPEVDRGTVERASINGHLEVRNLSFTYPGTERQVLDDISFSIEPGKMVALVGRSGSGKSTLANLIPRFYHHDKGQILLDGTEVEDFRLLNLRRHIAQVTQHVTLFSDTVANNIAYGDLAGAPREDIEKAAADAYAMDFIAQLPEGLDTQVGENGVLLSGGQRQRLAIARALLKNAPLLILDEATSALDTESERHIQAALDKVMKGRTTLVIAHRLSTIEKADLILVMDQGRIVERGSHAQLLAQNGYYSRLHAMGLEEPAPSGIA
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OBP1B_MOUSE
Sequence: MMVKFLLLALVFGLAHVHAHDHPELQGQWKTTAIMADNIDKIETSGPLELFVREITCDEGCQKMKVTFYVKQNGQCSLTTVTGYKQEDGKTFKNQYEGENNYKLLKATSENLVFYDENVDRASRKTKLLYILGKGEALTHEQKERLTELATQKGIPAGNLRELAHEDTCPE
What is the function of this protein?
Binds the chemical odorant 2-isobutyl-3-methoxypyrazine.
What are the official names of this protein?
Odorant-binding protein 1b, Odorant-binding protein IB.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATC_CARHZ
Sequence: MTISLKDVEHVAMLARLKLSDEEKEMYTKQLNDILKYAEQLQELDTENVKPTAHVLPIKNVFREDKVHQHLDPEKALANAPEREENFFKVPKII
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RBL2_RHOPT
Sequence: MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFAAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKMEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLKPQAA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase, RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type II subfamily.
Protein: AKIR1_XENTR
Sequence: MACGATLKRSMEFEALMSPQSPKRRRCAPLPGSPATPSPQRCGIRPEMQQGQQQPLPQLGGDRRLTPEQILQNIKQEYTRYQRRRQLEGAFNQSEAGVSNEVQASCSSLTAPSSPGSLVKKDQPTFSLRQVGILCERLLKDHEDKIREEYEQILNIKLAEQYESFVKFTHDQIMRRYGARPASYVS
What is the function of this protein?
Molecular adapter that acts as a bridge between proteins, and which is involved skeletal muscle development.  Functions as signal transducer for MSTN during skeletal muscle regeneration and myogenesis.
What are the official names of this protein?
Akirin-1.
What is the protein family that this protein belongs to?
Belongs to the akirin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEG3_MOUSE
Sequence: MADSFSLNDALAGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGQPAPGAFPGQPGAPGAYPQCSGGYPAAGPYGVPAGPLTVPYDLPLPGGVMPRMLITIMGTVKPNANRIVLDFRRGNDVAFHFNPRFNENNRRVIVCNTKQDNNWGKEERQSAFPFESGKPFKIQVLVEADHFKVAVNDAHLLQYNHRMKNLREISQLGISGDITLTSANHAMI
What is the function of this protein?
Galactose-specific lectin which binds IgE.  May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration.  Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.  In the nucleus: acts as a pre-mRNA splicing factor.  Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.  Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
What are the official names of this protein?
Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, IgE-binding protein, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Mac-2 antigen.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum- Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: RS7_LARHH
Sequence: MPRRREVPKRDVLPDPKFGSVELSKFMNVVMIDGKKAVAERIVYGALAQVEKKTGKNPIEVFSTAIANAKPVVEVKSRRVGGANYQVPVEVRPARRLALAMRWLREAARKRGEKSMDLRLAGELLDAAEGRGGAMKKRDEVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: THIM2_STRP2
Sequence: MQEFTNPFPIGSSSLIHCITNEISCEMLANGILALGCKPVMADDSREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKSLVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPGMSFLVTGPKDLVVSKNQVAVLGNGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCLAVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase 2, 4-methyl-5-beta-hydroxyethylthiazole kinase 2, TH kinase 2, Thz kinase 2.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: TRPF_RHIME
Sequence: MKTEVKICGLKTAEAVERAVALGASHVGFIFFPKSPRNIEPDDAGRLAARARGRAKIVAVTVDADNDGLDEIVSALDPDVLQLHGSETPERVLSIKALYGLPVMKALAVREASDLERIDPYLGIVDRFLLDAKPPAGSDLPGGNGISFDWRLLDALDGSVDYMLSGGLNAGNIADALALTGARAIDTSSGVESAPGIKDLTLMEAFFEAVRRAEA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: YAJC_ECOLI
Sequence: MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVLPKGTMKAL
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes (PubMed:27435098).  The SecYEG complex is essential for assembly of a number of proteins and complexes, assembly is facilitated in the presence of the SecDF-YajC-YidC subcomplex (PubMed:27435098).
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ANM1_RAT
Sequence: MAAAEAANCIMEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR
What is the function of this protein?
Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, FMR1, ILF3, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15, EWS, HABP4, SERBP1, RBM15, FOXO1, CHTOP and MAP3K5/ASK1 (PubMed:12737817, PubMed:15837430, PubMed:18492485, PubMed:22095282, PubMed:19405910).  Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation (By similarity).  May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway (By similarity).  Methylates RBM15, promoting ubiquitination and degradation of RBM15 (By similarity).  Methylates FOXO1 and retains it in the nucleus increasing its transcriptional activity (By similarity).  Methylates CHTOP and this methylation is critical for its 5-hydroxymethylcytosine (5hmC)-binding activity (By similarity).  Methylates MAP3K5/ASK1 at 'Arg-85' and 'Arg-87' which promotes association of MAP3K5 with thioredoxin and negatively regulates MAP3K5 association with TRAF2, inhibiting MAP3K5 stimulation and MAP3K5-induced activation of JNK (PubMed:22095282).  Methylates H4R3 in genes involved in glioblastomagenesis in a CHTOP- and/or TET1-dependent manner (By similarity).  Plays a role in regulating alternative splicing in the heart (By similarity).
What are the official names of this protein?
Protein arginine N-methyltransferase 1, Histone-arginine N-methyltransferase PRMT1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Cytoplasm, cytosol. Cytoplasm. Note=Mostly found in the cytoplasm. Colocalizes with CHTOP within the nucleus. Low levels detected also in the chromatin fraction (By similarity).
Protein: NUOG_STRCO
Sequence: MTVTTSTPSGGGAAAVPPEDLVTLTIDGAEISVPKGTLVIRAAEQLGIEIPRFCDHPLLDPAGACRQCIVEVEGQRKPMASCTITCTDGMVVKTQLTSPVAEKAQHGVMELLLINHPLDCPVCDKGGECPLQNQAMSHGQSDSRFEGKKRTYEKPVPISTQVLLDRERCVLCARCTRFSNQVAGDPMIELIERGALQQVGTGEGDPFESYFSGNTIQICPVGALTSAAYRFRSRPFDLISSPSVCEHCSGGCATRTDHRRGKVMRRLAANEPEVNEEWICDKGRFGFRYAQQRDRLTTPLVRNAEGELEPASWPEALQIAAQGLLASRGRTGVLTGGRLTVEDAYAYSKFARVALDTNDIDFRARVHSAEEADFLAAHVAGRGRDLGGSSRTESGGGAGVTYTSLEKAPAVLLVGFEAEEEAPGVFLRLRKAWRKHGQKVFSLATHATRGLEKAGGTLLPAAPGTETEWLDALASGVGLEEGGTQAAEALRAEGAVIVVGERLASVAGGLTSAVRTSAATGARLVWIPRRAGERGAIEAGALPSLLPGGRPATDPRAREEVAALWGLADLPHRYGRDTGEIVEAAARGELQALLVAGVEVADLPDPTRARAALDEAGFVVSLELRPSEVSERADVVLPVAAVAEKPGTFLNWEGRVRFFEAALKPDQMTRRLAPTDARVLQMLADAMDVHLGLPDLRTTRAEIDRLGAWDGPRAGEPLQTASALPRPAAGEAVLAGHRLLLDQGLLQQGDEALAGTRHAARARLSAATAAEAGVKDGDVLAVTGPAGAVELPLQVTEMPDRVVWLPLNSAGSGVASDAGVLPGTLVRIGPATPAGAAPKEVEA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit G, NADH dehydrogenase I subunit G, NDH-1 subunit G.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
Protein: ASSY_PYRAE
Sequence: MGASKIVLAYSGGLDTTVAVKWLSEKFGAEVYTVTVDVGQEDDFSKIEERAYKAGAVQHFYIDAKREFAEEYIARAILMNGMYEGVYPLGTALARPLIAAKVVEVARRLGADAVAHGSTSKGNDQVRFDVTVKALAPDLKIIAPARIWGMTRAEEIEYAKRHGLPVGEEHKKYSIDDNLWSRSIEGGPIDDPLAEPPEDAFKWTVSPDKAPHDPTYLTIEFEKGLPVAVNGEKMSLASIISLLNHVGGANGVGRIDHIENRLVGFKSREVYEAPAAVILYHAHRDLEKMVLTPRELRFKHYVLDPQWADLVYQGLWVEPLRNALEKAAEEMERWVSGEVRVKLYKGSLWVVGRESPYGGYSKELADYSAGWYPSDEEARGFIEMWSLHSLTALRRRK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODPB_BACSU
Sequence: MAQMTMIQAITDALRTELKNDENVLVFGEDVGVNGGVFRATEGLQKEFGEDRVFDTPLAESGIGGLALGLGLNGFRPVMEIQFFGFVYEVMDSVSGQMARMRYRSGGRWTSPVTIRSPFGGGVHTPELHADSLEGLVAQQPGIKVVIPSTPYDAKGLLISAIRDNDPVVFLEHMKLYRSFRQEVPEEEYTIELGKADVKREGTDLSIITYGAMVHESLKAADELEKDGISAEVVDLRTVSPLDIDTIIASVEKTGRAIVVQEAQKQAGIAANVVAEINDRAILSLEAPVLRVAAPDTVFPFSQAESVWLPNHKDVLETARKVLEF
What is the function of this protein?
The B. subtilis PDH complex possesses also branched-chain 2-oxoacid dehydrogenase (BCDH) activity.
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta, S complex, 36 kDa subunit.
Protein: Y5188_ARATH
Sequence: MKSIHGFLLFLITAYVILESVQAQDQLGFISLDCGLVPKNATYTEKTTNITYKSDANYIDSGLVGRISAEYKAQLQQQTWTVRSFPEGERNCYNFNLTAKSRYLIRATFTYGNYDGLRQVPKFDIHIGPSKWTSVKLDGVGNGAVLEMIHVLTQDRLQICLVKTGKGIPFISSLELRPLNNNTYLTQSGSLIGFARVFFSATPTFIRYDEDIHDRVWVRQFGNGLKSISTDLLVDTSNPYDVPQAVAKTACVPSNASQPLIFDWTLDNITSQSYVYMHFAEIQTLKDNDIREFNITYNGGQNVYSYLRPEKFEISTLFDSKPLSSPDGSFSLSFTKTGNSTLPPLINGLEIYKVLDLLELETDQDEVSAMINIKATYDLSKKVSWQGDPCAPKSYQWEGLNCSYPNSDQPRIISLNLAENKLTGTITPEISKLTQLIELDLSKNDLSGEIPEFFADMKLLKLINLSGNLGLNSTIPDSIQQRLDSKSLILILSKTVTKTVTLKGKSKKVPMIPIVASVAGVFALLVILAIFFVVRRKNGESNKGTNPSIITKERRITYPEVLKMTNNFERVLGKGGFGTVYHGNLEDTQVAVKMLSHSSAQGYKEFKAEVELLLRVHHRNLVGLVGYCDDGDNLALIYEYMANGDLKENMSGKRGGNVLTWENRMQIAVEAAQGLEYLHNGCTPPMVHRDVKTTNILLNERYGAKLADFGLSRSFPVDGESHVSTVVAGTPGYLDPEYYRTNWLSEKSDVYSFGVVLLEIVTNQPVTDKTRERTHINEWVGSMLTKGDIKSILDPKLMGDYDTNGAWKIVELALACVNPSSNRRPTMAHVVTELNECVALENARRQGREEMHTSGYVDFSRSSASEFSPGAR
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At1g51880.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TRM61_RAT
Sequence: MSFVAYEELIKEGDTAILSLGHGSMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCSRGGWVYVLHPTPELWTVNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRSIAPTGHLHTVEFHQQRADKAREEFQQHRVSQWVTVHTQDVCRSGFGVVHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAAHGFTELSTLEVLPQVYNVRTVSLPLPDLGADDLEGNVGSDATPFRSGTPMKETVGHTGYLTFATKTPG
What is the function of this protein?
Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.  Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A, mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A, tRNA(m1A58)-methyltransferase subunit TRMT61A, tRNA(m1A58)MTase subunit TRMT61A.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRG_HAES1
Sequence: MATNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTQDGAETDLDLGHYERFIRTKMTKRNNFTAGKIYSEVLRKERRGDYLGATIQVIPHITNEIKSRVIDGAAGYDVAIVEVGGTVGDIESLPFLEALRQLAVQVGRERTIFMHLTLVPYIPTAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRMIPPNERAKIALFCNVPERAVISLKDVSSIYQIPALLKSQGLDDFICQRFRLDCQEADLSEWEKVLYQEANPTGEVTIGMVGKYTELPDAYKSVNEALKHAGLTNRLTVNIKYIDSQDVETKGIDILKDLDGILIPGGFGYRGVEGKILTAQYARENNVPYLGICLGMQVAFIEYARHVAGLKGANSSEFDRTCEYPVIALITEWQDAEGNVEVRSDESDLGGTMRLGAQQCHLVAGSLAHQLYGSDIIEERHRHRYEVNNVIRPQVEKAGLKVTGLSADKKLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASENRKK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.