PharMolix/UniProtQA huggingface dataset:
Protein: PA_I34A0
Sequence: MEEFVRQCFNPMIVELAEKTMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESKIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLAEQSLPPNFSSLENFRAYVDGFKPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLHDAIKCMKTFFGWKEPNIVKPHEKGINPNYLLAWNQVLAELKDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFEDCKDISDLKQYDSDEPEQRSLASWIQSEFNKACELTDSGWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQVESMVEAESSVKEKDMTKEFFENKSKTWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYGAIEECLINDPWVLLNASWFNSFLTHALK
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: CD9_RAT
Sequence: MPVKGGSKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNHSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAVWGYTHKDEVIKELQEFYKDTYQKLRNKDEPQRETLKAIHMALNCCGIAGGVEQFISDICPKKQVLESFQVKSCPDAIDEVFHSKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRSREMV
What is the function of this protein?
Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity).  Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity).  In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity).  In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (By similarity).  Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity).  Acts as a receptor for PSG17 (By similarity).  Involved in platelet activation and aggregation (By similarity).  Regulates paranodal junction formation (By similarity).  Involved in cell adhesion, cell motility and tumor metastasis (By similarity).
What are the official names of this protein?
CD9 antigen.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Secreted, extracellular exosome. Note=Present at the cell surface of oocytes. Accumulates in the adhesion area between the sperm and egg following interaction between IZUMO1 and its receptor IZUMO1R/JUNO.
Protein: PSBZ_NICSY
Sequence: MTLAFQLAVFALIATSLILLISVPVVFASPDGWSSNKNVVFSGTSLWIGLVFLVGILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: PA_I96A2
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVEPEDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFLKTTPRPIRLPDGPPCFQRSKFLLMDSLKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPSVVKPHGKGINPNYLLSWKQVLAELQDIESEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDDCKDIIDLKQYDSDEPELRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENRSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: AROE_STAS1
Sequence: MKYAVIGNPIDHSLSPVMHNANFAALNDLSSYEAINIRNEDFHRIKEIINDKALSGFNVTIPHKERIIPYLDEIDEQSKTVGAVNTVKIVDGKWIGYNTDGIGYVTGLRQVYPDLEDAYILILGAGGASKGLANELKKFVRPKLTVANRSMDRFESWQLEVNKISLQEAEAALSEFDIIINTTPAGMNQNKEVIINLDNLDSHTLVSDIVYVPFKTPILEIAEAKGNPIHNGLDMFVYQGAESYRIWTGELPQIQIMKDTVLKYL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: TIG_SYNJA
Sequence: MQVTQEKRPGSRVGLKIVVEADQVKRSYEKTLRQLERNIQIPGFRKGKAPRNLVIRQVGRERVMASAVDDLINEAIQQALKDTQLHPISRFELDDKVEQLLDRFNPEADFSFSGYVEVYPEARVGQYKGLTVTATRVTVKPEQIDQLIDRWRDQRATLLPVEDRPAQLGDVVVIDFQARDAEGNPLEEIAAQDFQLELKEENFIPGFVAGVVGMQLDQTKEITATFPDDYFRKELAGKTVTFTVCLKEIKTKELPELDDAFVQEISEFQTVAELREHLQKRLEQDALRQSEENLETAILNAILETTEVDLPETLVEQETTQLLARSLQSLQQQQGVTPGEIRKFLSQLPPETLNQLMERHRPEAINRLRRTLALSAIVRQEQIAVGPNELEVEVEEVMAAYAQQGQKLDRERVRQAVHEDLLANKVMAWLKSQTTVNWVDSEGNPTEPPTLSPRSEGEDRQERSESARAGVPETEFEAEKPEGSAIPEAVEPPVDAKAEGEVATEPQAALPSVEAEASGIPEAVEPSAEAATDPAGLQLEQAVAETPKAGKKSKKDK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PDXJ_PROMA
Sequence: MTSLGVNIDHIANIRQARLANEPDPVQMALLAELGGADGITIHLREDRRHIQDRDLKLLRETIKSRLNLEMAATTEMIEIALDLKPDMITLVPERREEITTEGGLDVASNAKSLKEIVTKMESCCIPTSLFVDANSKQLEASSKIGATWVELHTGPYARASWKNQPLEFAKISEGVARARNLGLRVNAGHGLTYQNVEPIASITEMEELNIGHTIIARAIAIGLKEAVKEMKELIKNPRHEPFFGS
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGI_RALSO
Sequence: MKTLHRCIGVALLALGALAGTAHADRIKDLTTIAGVRENALIGYGLVVGLDGSGDQTTQTPFTIQSFNNMLSQFGINVPSGASIQLKNTAAVVVTASLPAFVRPGQTIDVTVSSIGNAKSLRGGTLLLTPLKGVDGQLYALAQGNVVIGGAGASANGSKVQINQLGAGRIANGATVERTVQATVGEAGSIQLDTGTTDFGTVQNIVNAINKQFGADTAEAADGRTVNVRAPALAADRVGFVAKLQNIEVTPAQAAARVVVNARTGSVVMNQQVKLEPCAVAHGNLSVTISTEPVVSQPAPFSQGQTVAGARSNIEVKQQGGSLINVKGGTNLADVVKAINAIGANPQDLISILQAMKAANALRADLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: YJ26_YEAST
Sequence: MEQMHSLESSLPPEQPPTKQAIESLNLELSQEFKLAANAVTRLYRVANEKNSLTKHQGYLTCLDDILCALDSNVTADELRAWCYKRRNDILSNSQDKSLNPVKERERKLNKFSENQHRENEAHKEPFEKDSAVKYNFSFNESNGDLSNINENIAPKFRLSMPPLSVEHPPRNASRIKSWKARTINHGRGDTRNLNDITGLGHERERDRENTHYEKKPKLDSDSEVDIRSFRQDMDL
What are the official names of this protein?
Uncharacterized protein YJR056C.
Protein: ILVD_PROMS
Sequence: MNKLRSSAITQGVQRSPNRSMLRAVGFNDEDFNKPIIGVANGYSTITPCNMGLNKLALKAEESIKRSGGMPQMFGTITVSDGISMGTEGMKYSLVSREVIADSIETACNAQSMDGVLAIGGCDKNMPGAMIAIARMNIPSIFIYGGTIKPGKLHGEDLTVVSAFEAVGQLTSGKINEERLIQVEKNCIPGAGSCGGMFTANTMSAVIEVLGLSLPHSSTMAAEDLEKELSADKSAEILVSAIEKDIRPLDLMTKKAFENAISVIMAIGGSTNAVLHILAIANTAGIDININDFERIRQKVPVICDLKPSGKYVTVDLHKAGGIPQVMKILLNAGLIHGDCKNIEGKTISEYLQNIPDKPPTNQNVIRDIDNPLYKKGHLAILKGNLASEGSVAKISGVKNPVLTGPAKIFESEEDCLKSILNNDIKAGDVVVIRNEGPVGGPGMREMLAPTSAIVGQGLGEKVALITDGRFSGGTYGLVVGHIAPEAAVGGNIALIKQGDLITVDAVKQLIEVDLSDEELEKRKKDWVKPIQKYKRGILSKYSRIVSTSSLGAVTDL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RS20_STAES
Sequence: MPNIKSAIKRVRTTETAEERNISKKNAMRTAVKRAKTAISTDAENKDELLRFAIKQVDKASQSNLIHSNKADRIKSKLMSANK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PDXB_BLOPB
Sequence: MRILADKNIPHIFKLFGLHNTVTICEGRGISAKDVRDIDILIVRSVTKVNKLLLDDSSVKFVGTATAGVDHIDQNYLKKYGINFVYAPGNNAVAVVEYVFSALLWLAQRGRFFLRDKIVGIVGVGHIGSLLNERLRNFGIHTLLCDPPLEKINSSKPWKSFETLVAEADILTFHTPLIYYGDYPTWHMVDIDVLEALPSNRILINTCRGSVIDNNALLKVLENGKKLNVILDVWETEPELSLPLLSYADIGTPHIAGYSTESKTRSILQIYNAYCNFFNIFNVINLSALDSPVIYYLRVQKEIDETLLHKLVKFVYNIQYDDVILRRFAAKSGGFDKIRKHYLARREWSSLRVETYIDSNNEILTKLGFNVCCV
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX15_TITOB
Sequence: MKGIILLISCLMLIEVVVGGKEGYPLDSSGCKAGCFFGTNSWCNTECKRKSAAKGYCAWPSCYCYEFTDDSKIWNAKTNKCYK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin To15, T-beta* NaTx1.4.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ASNS1_LOTJA
Sequence: MCGILAVLGCSDFTQAKRVRVLELSRRLKHRGPDWSGLHQHGDCYLAHQRLAIVDPASGDQPLFNEDKSIIVTVNGEIYNHEELRKQLPNHQFRTGSDCDVIAHLYEEHGENFMDMLDGIFSFVLLDTRDNTFIVARDAIGVTSLYIGWGLDGSVWISSEMKGLNDDCEHFEVFPPGHLYSSRERAFRRWYNPTWFSESIPSAPYDPLAVRHAFEKAVIKRLMTDVPFGVLLSGGLDSSLVASITSRYLATTKAAEQWGSKLHSFCVGLEGSPDLKAAKEVADYLGTVHHEFTFTVQDGIDAIEEVIYHVETYDVTTIRASTPMFLMSRKIKSLGVKWVISGEGSDEIFGGYLYFHKAPNKEEFHTETCRKIKALHQYDCLRANKSTFAWGLEARVPFLDKEFINVAMNIDPEYKMIKRDEGRIEKYILRRAFDDEEKPYLPKHILYRQKEQFSDGVGYSWIDGLKDHAAKHVTDKMILNAGNIFRHNTPLTKEAYYYRMIFERFFPQNSARLTVPGGPTVACSTAKAVEWDAAWSNNLDPSGRAALGVHLSAYDDKQNNLINNKPVEFEKLIPMEAPSLGVAIHS
What are the official names of this protein?
Asparagine synthetase [glutamine-hydrolyzing] 1, Glutamine-dependent asparagine synthetase 1.
Protein: CH10_BACVZ
Sequence: MLKPLGDRVVIELVESEEKTASGIVLPDSAKEKPQEGKIVAAGSGRVLESGERVALEVKEGDRIIFSKYAGTEVKYEGTEYLILRESDILAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1034_HAEIN
Sequence: MPSFDIVSEITLHEVRNAVENANRVLSTRYDFRGVEAVIELNEKNETIKITTESDFQLEQLIEILIGSCIKRGIEHSSLDIPAESEHHGKLYSKEIKLKQGIETEMAKKITKLVKDSKIKVQTQIQGEQVRVTGKSRDDLQAVIQLVKSAELGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein HI_1034.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: PDXS_SULIK
Sequence: MRLYELSFAQIEDFFYKLAEVKDIIKDSGLMEFLPELKKLDSTIQTGTTRVKHAFPIFQKGGVVMDITNVQQAQIAEEAGAVAVMVLDKLPYDVRKSGGVARMADPKIIGEVMNSITIPVMAKVRIGHYYEAKLLEALGVDMIDESEVLTPADEEHHINKWEFSVPFVNGARNLGEALRRTAEGASMIRTKGEAGTGNVSEAVKHMKIINSEIRSLISMSEEDRVKKAREYQVPYQLVELTAKIKRLPIVNFAAGGIATPADAALMMWLGADGLFVGSGIFKSQDPDERAKAVVLAAACWEYPEIVLEAQKMISEQKSMMGIDIKSLKPEELLQVRGL
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: Y3401_SHEON
Sequence: MGRAYQNRKESMAKTAGQKTRLYSRYGKEIYVVAKQGGVEPDGNLSLRRLIERAKKDQVPAHVIERAIDKAKGGGGEDYDTARYEGFGPGNCMVIVDCLTDNVKRTFTEVRQAFVKNDAKLGTPGTVGHMFDQSAVFVFPGEDEDAILEILMMADVDVNDVEVEDGMISVIAPHTEFFKVKTALTDAMPDINFEVENITFVPQTMTPVSGEDVAVFDKFIAALEDCDDVQNVYHNAEIQD
What are the official names of this protein?
Probable transcriptional regulatory protein SO_3401.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_RHOP2
Sequence: MASRHSPQTAAQPDAADKAQALRLTPVSRETETRLDAYLDLLRLWQAKTNLVAPSTLPQLWTRHVADSLQLLALAPTARRWLDFGSGGGFPGIVLACAMAEHDGGHVTLVERNAKKAAFLREALRVTGAPGTVMLADIGDNVDRFPRALDCITARAVAPLHQLIGFAAPLMTEGSKVLFLKGQDVEAELTEATKYWKIEPQLHASLTGGQGWIVELDRIVRHAPSTTNPEAAAHDRH
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOTB_ECOSM
Sequence: MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASTLVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLEEQTQ
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SF3B2_HUMAN
Sequence: MATEHPEPPKAELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGNREELVERLQSYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLPGIPMPPPPLGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDMGQIGVRTPLGPRVAAPVGPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDARSSLGQSASETEEDTVSVSKKEKNRKRRNRKKKKKPQRVRGVSSESSGDREKDSTRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAAPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643).  SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA.  Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937).  May also be involved in the assembly of the 'E' complex (PubMed:10882114).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077) (Probable).
What are the official names of this protein?
Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, Spliceosome-associated protein 145, SAP 145.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: PURA_RUTMC
Sequence: MSKNVVIIGTQWGDEGKGKVVDLITDKVASVVRFQGGHNAGHTLVINGKTTILHLIPSGILRNHVECLIGHGVVLSMSALLKEIAELEVADIDTTKRLKISPGCPLILPYHIELDNAREIKRGKAAIGTTGNGIGPAYEDKVARRGLRVSDLLDPNLFASKLKEVMEYHNFFLTHYYNANPVDYQTTLDEVLSQVEQTKHMIVDVTEQIHQHIANDENILFEGAQGALLDIDQGTYPFVTSSNTTSGAAVTGSGIGVTDIDYVLGIVKAYTTRVGGGPFPTELIYDVALDKGDEIGKVLGTVGHEFGATTGRQRRCGWLDMVTLKRSFNLNAVTGICLTKLDVMDTLETIKICTSYEIDGVETTIPPFSAEDYAKAKPIYIKIPGWKTSTIGTDSFDSLPVEAQSYIRKIEQLANLPVDILSTGPDRLQTLILKHPFE
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYNG1_RAT
Sequence: MDGIVEQKSVLVHSKIGDAGKRNGLINTRNFMAESRDGLVSVYPAPQYQSHRLVASAAPGSLEGGRSDPVQQLLDPNTLQQSVDSHYRPNIILYSDGVLRSWGDGVATDCCETTFIEDRSPTKDSLEYPDGKFIDLSGDDIKIHTLSYDVEEEEELQELESDYSSDTESEDNFLMMPPRDHLGLSVFSMLCCFWPLGIAAFYLSHETNKAVAKGDFHQASTSSRRALFLAVLSITIGTGIYVGVAVALIAYLSKNNHL
What is the function of this protein?
May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation.
What are the official names of this protein?
Synapse differentiation-inducing gene protein 1, SynDIG1, Dispanin subfamily C member 2, DSPC2, Transmembrane protein 90B.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Early endosome membrane; Single-pass type II membrane protein. Postsynaptic density membrane. Synapse. Cell projection, dendrite. Cell projection, dendritic spine. Note=Shuttles between the cell surface and early endosome membrane.
Protein: CSPL5_PHYPA
Sequence: MEDPKGAWQSDVFDNGRDFKPHDKAPANVTAGTTPPMYNVGAGGSEGNSKALSIISIVLRCLSIMFNVVSLGVIASNQGKSYFVVWRTLNSSNMQYLFAINVIVLVYCVVQLILSIINLVQGKMVLSGPTQPASTITYICDQGLTYMLMAGFGAGVALQASVDKGESGMLDCSGANEFCGKNKASAALSFLGFVCIALSANLNYLRLYFMAAK
What are the official names of this protein?
CASP-like protein UU2, PpCASPLUU2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HUTP_BACCQ
Sequence: MLLQGTHRIGRMAMLLALADENESPVLSIPKGWKYCTGKVGSMNSQKVVAAMETAAKSNQVIETDVYRETHALYHAIMEALYGVTRGQIQLADVLRTVGLRFAIVRGTPYDGKKEGEWVAVALYGTIGAPVKGSEHEAIGLGINHI
What is the function of this protein?
Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
What are the official names of this protein?
Hut operon positive regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the HutP family.
Protein: PYRB_MYCTO
Sequence: MTPRHLLTAADLSRDDATAILDDADRFAQALVGRDIKKLPTLRGRTVVTMFYENSTRTRVSFEVAGKWMSADVINVSAAGSSVGKGESLRDTALTLRAAGADALIIRHPASGAAHLLAQWTGAHNDGPAVINAGDGTHEHPTQALLDALTIRQRLGGIEGRRIVIVGDILHSRVARSNVMLLDTLGAEVVLVAPPTLLPVGVTGWPATVSHDFDAELPAADAVLMLRVQAERMNGGFFPSVREYSVRYGLTERRQAMLPGHAVVLHPGPMVRGMEITSSVADSSQSAVLQQVSNGVQVRMAVLFHVLVGAQDAGKEGAA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: GLGS_SALPK
Sequence: MNNNNVYSLNNFDFLARSFARMQAEGRPVDIQAVTGNMDEEHRDWFCKRYALYCQQATQAKKLELEH
What is the function of this protein?
Major determinant of cell surface composition.  Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
What are the official names of this protein?
Surface composition regulator.
What is the protein family that this protein belongs to?
Belongs to the GlgS family.