PharMolix/UniProtQA huggingface dataset:
Protein: LGT_SALTI
Sequence: MTSSYLHFPDFDPVIFSIGPVALHWYGLMYLVGFVFAMWLAVRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPLFLDNPLYLFRVWDGGMSFHGGLIGVILVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPDFRFAMLFPGSRAEDIALLPSHPQWQPIFDTYGVLPRHPSQLYELALEGVVLFIILNLFIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIIAGAIMMVWAYRRRPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: S38A2_MOUSE
Sequence: MKKTEMGRFNISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETDFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGHKAYGLAGKLAASGSITMQNIGAMSSYLFIVKYELPLVIKALMNIEDTNGLWYLNGDYLVLLVSLVLILPLSLLRNLGYLGYTSGLSLLCMIFFLIVVICKKFQIPCPVEAALVANETVNGTFTQAALALAFNSTADDACRPRYFIFNSQTVYAVPILTFSFVCHPAVLPIYEELKSRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYGHVESELLHTYSEIVGTDILLLVVRLAVLVAVTLTVPVVIFPIRSSVTHLLCPTKEFSWLRHSIITVTILSFTNLLVIFVPTIRDIFGFIGASAAAMLIFILPSAFYIKLVKKEPMRSVQKIGALCFLLSGIVVMIGSMGLIVLDWVHDASAAGGH
What is the function of this protein?
Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane (PubMed:34406367).  The trasnport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient and cotransports of neutral amino acids and sodium ions with a stoichiometry of 1:1.  May function in the transport of amino acids at the blood-brain barrier (By similarity).  May function in the transport of amino acids in the supply of maternal nutrients to the fetus through the placenta (PubMed:16365304).  Maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate (By similarity).  Transports L-proline in differentiating osteoblasts for the efficient synthesis of proline-enriched proteins and provides proline essential for osteoblast differentiation and bone formation during bone development (PubMed:34406367).
What are the official names of this protein?
Sodium-coupled neutral amino acid symporter 2, Amino acid transporter A2, Solute carrier family 38 member 2, System A amino acid transporter 2, System A transporter 1, System N amino acid transporter 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes. Enriched in the somatodendritic compartment of neurons, it is also detected at the axonal shaft but excluded from the nerve terminal.
Protein: RK36_STIHE
Sequence: MKVRASVKKICANCRLIRRKRKILVICVNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DER_BORPD
Sequence: MSFKPVVALVGRPNVGKSTLFNRLTRSRAALVADYSGLTRDRHYGEGRVGDTPFIVIDTGGFEPVAKTGILREMARQTRQAIAEADVVVFLVDARAGVNAHDHEIAQLLRKSGQQRVVLAVNKAEGMGVGNATSEFHELGLGTPYPISAAHGDGIVDLIGLALQDLVEPEPEPAPDAADLPPDHRIKLAIVGRPNVGKSTLINTLLGEERVIAFDLPGTTRDAIEIDFERDGRKYTLIDTAGLRRRGKVFEAVEKFSVIKTLQAIEASNVVLLMLDAQTEVSEQDAHIAGFVLETGRAVVVAINKWDGLDIDQRERIEREFRRKLRFLSFAPTHTISALKGQGIKPVLKSVVAAHAAAFAKLSTPKLTRELHAAVEQQPPPRKGIFRPKMRYAHQGGQNPPLVIIHGNALDAIPDSYRRYLETRFREAFKLDGTPLRIEFKSSRNPYTQES
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PTHP_GEOSE
Sequence: MAEKTFKVVSDSGIHARPATILVQTASKFNSEIQLEYNGKTVNLKSIMGVMSLGIPKGATIKITAEGADAAEAMAALTDTLAKEGLAE
What is the function of this protein?
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes.  Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources.  P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_PSEPU
Sequence: MRVILLGAPGAGKGTQAKFITEKFGIPQISTGDMLRAAVKAGTPLGLELKKVMDAGQLVSDELIISLVKERIAQPDCANGCLFDGFPRTIPQAEAMVAAGVDIDAVVEIAVDDEEIVGRMAGRRVHLASGRTYHIQYNPPKVEGKDDETGEDLIQRDDDKEETVRHRLSVYHSQTKPLVDFYQKLSAANGGKPKYSHIEGVGSVEAITAKVLAALS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARFM_BACSU
Sequence: MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFLHSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDILILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS
What is the function of this protein?
Activates, in anaerobic conditions, the transcription of the fermentative operons lctEP and alsDS, of the hmp gene encoding a flavohemoglobin-like protein, the nitrite reductase operon nasDE and the heme biosynthesis genes hemN and hemZ.
What are the official names of this protein?
Probable transcription regulator ArfM, Anaerobic respiration and fermentation modulator.
Protein: HDRC2_METJA
Sequence: MAVIKLDEVNKNFVNEVIEAGKLVLGEDIVKSIKACYQCGTCTGSCPSGRRTAYRTRKVLRKVLLGLDDVLDSDDIWYCTTCYTCYERCPRDVKITEIIKTLRNIAAQKGNMALAHRKTASYVLRFGHAVPANNQIVELRGKLGLPAKSPTAQFSEKDLEEVRTLIKELKFDKLIAFDWEKMDLKE
What is the function of this protein?
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
What are the official names of this protein?
CoB--CoM heterodisulfide reductase iron-sulfur subunit C 2.
What is the protein family that this protein belongs to?
Belongs to the HdrC family.
Protein: MURC_SHESH
Sequence: MSKNQEKYSQLRSIIPEMRRVKHIYFVGIGGAGMGGIAEVLVNEGYKLSGSDIAENAVTQRLASLGAKIHIGHREEQVHGADVVVVSTAISADNPELLEAQALRIPVVQRAEMLAELMRYRHGVAVAGTHGKTTTTSLIASVYGQAERDPTFVIGGLLNSAGTNARLGHSRYLIAEADESDASFLHLQPMVSVVTNIEADHMDTYEGDFEKLKSTFIDFLHNLPFYGVAVMCIDDPVVRELLPKVGRKIVTYGFSEDADVQALNFVQEAYLSRFTLRRAGVEDMEVVVNLPGQHNVLNALAAIAVATEDEIDDAAIIQALADFQGIGRRFEQLGCFDTNKGEMVLVDDYGHHPSEVAATIKAAKAGWPEKRLVMVYQPHRYSRTRDLYDDFVEVLSQVDCLLLLDVYAAGESPVPGADSRALCRSIRQRGQLDPIFVSDSEQLLSLLPDVLQAGDLVLTQGAGNIGAIAKQLSLSSLGFDLAASGTGKE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APX6_ARATH
Sequence: MTTTTASLVKTFLFRCDSFSSFKFKCKFESPAKTRLLSPATEKHVVRSSRAWRIRCLSDDPGSSHVFVASRRKMVVLLSTVQLLSHMLPQNGNAAEIYPVMQNEIRKVVTKGKAAGVLRLVFHDAGTFELDDHSGGINGSIAYELERPENIGLKKSLKVLAKAKVKVDEIQPVSWADMISVAGSEAVSICGGPTIPVVLGRLDSAQPDPEGKLPPETLSASGLKECFKRKGFSTQELVALSGAHTIGSKGFGDPTVFDNAYYKILLEKPWTSTSKMTSMVGLPSDHALVQDDECLRWVKRYAEDQDKFFEDFTNAYIKLVNSGAKWNML
What is the function of this protein?
Plays a key role in hydrogen peroxide removal.
What are the official names of this protein?
Putative L-ascorbate peroxidase 6, AtAPx08.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Ascorbate peroxidase subfamily.
Protein: THR_DROPS
Sequence: MSADIVKQLKGTRSDVKAAATTIELKFKEFSKGIGINDASFPLRYELSVLRQLCLALKDNLHQHADLYCGIAATMLPHVEPYEEKPSLWEAHLTSLRYIHHGLCQEKSLTECQKMYGLIRSQPCRLQEEADYKFYLDIHLTHFNGIYLQMQKETLPLAATDELYYALEAMGVLFDTMHQRKVAKNAALLVQLNDSLFSKRSKAFLKYLSALPPESTTKMYDPLLKLLSCSWATPSSELTNQFTEYLGLVLALVQIDMFSIEAPLEQQLALKLLRICRDLYKDVSPQNYSIQLLYYYVKLMYVREATADFKQTYIDLCKKFVYFFEHKGATHAKEQWFMDLLVFFQRLQTLLHQSSNKPPLDIFWQQLEGDDSSEVYTAHFQLLHGCLGLAVNVVRSPLGTSCSNEACKSIRRHCLLYFGMCALEAYINWQPTTEQKADKAPYKPLLGILGYTLDVAKSMKCLGPSAMELVKLVRLLALVAEKVSCPEQMSLVLAFLEPLQHLRPLIASQDMLSVLRRIYKASVHCKSSDMANRLQSTYLAALTNPSRLRSQLFAHYHNANNTEKCVYEWHESSPMPNPLTPAQTKQLYDVDLLAVLHFLSAPPVPLLQSLLRCRHNDYHLALLARKMRTDSEVVRQCEELRSQLHSTALKQPLSRMQQLAIGHTSISVLLEALEAQKTKFSIKETAENCLEELIVKNNLLELNIKREHRLVELATSAIAGFAAFFERADTEPLGCDDTPIDWEALIDDAVAAAMALSTMGYMAQADEAWLLILRIGQMLDERFTYLRALTHFLGQDHLNSNQQLQLSEEVDRAQELLDDLWPQLQNGWFFKRQHTIVMLCLCHMASYYARQDCLCHAQLLLLQAEELRAQFDERVGKSDIVQITIQTVRFRLEYLRNKRCSSLPRRPTPLRQLDTLVDSVRNYCTVSSVDLGALQLLLADLVRESTECAANRLTERFAFYGTMLNLVLQSGMALRTIEVLISWLWMNLQMEYLDQAQSKLRLLDHLLAIKPLSRTLVEQTSATYVPAIAAKEDLKANAMSELTSNMLLMQLVEPIRKQNQMDVATIKSLPMHEPIPTSHQLQRYVSKQGTPPHLRDSMQLQCIYFIVGCLHARFSFLKRENDQLDDFYVGAGNWLQEDPVRTATLGSMLLVHELYHLNYLRFRKKHKEALSYAEAGLKSVYQTADINYSFNFMVQLKTARLELHPVGKARAKTIRRALAFNTSPEDKRRKGVVEGSIKAKSSARKTPRFKIYTELELRPPIGCSNSSSSSSKSGNENTPPSDHVDLNACQAIEISDDDAASVSASTPAPSQLKRSQSVPAKATKTRSARVGSQLKVPEIIELDDTMEETPSTSTAATVKRYPTTDARSSRARNRQLEETPATTRGRPRRKVPEPAPQQETVSLRPRQRN
What is the function of this protein?
Required specifically for chromosome disjunction during all mitoses; maternally provided protein is sufficient until mitosis 14 then zygotic protein is required.  Involved in formation and/or maintenance of epithelial structures: bud extension during Malpighian tubule development, and foregut and hindgut morphogenesis (By similarity).
What are the official names of this protein?
Protein three rows.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_BURO0
Sequence: MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVREYANQILGMQLVTHQTGPEGQKVNRLMIEEGADIKQELYVSLVVDRISQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQADDLAAKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSGDGKVTALDAKFNFDSNALFRHPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: HIPK4_MACFA
Sequence: MATTQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLRALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAARKAHHFFKRNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRNAHETTHYYQLSLRSYRLSLQVEGKPPAPVVAAEDGTPYYRLAEEKEAAGMGSVASSSPFFREEKAPGMQRAIDQLDDLSLQEAGHGLWGETCTDVVSDMMAPLKAAITGRHMPDSGPEPILAFYSSRLAGRHKARKPPAGSKSDSNLSNLIRLSQVSPEDDRPCRGSSWEEGEHLGASAEPPAILQRDGDGPNIDNMTMEAERPDPELFDPSSCPGEWLSEPDWTLEGVRGPRAQGLPPRRSHQHGPPRGATSFLQHVTGHH
What is the function of this protein?
Protein kinase that phosphorylates TP53, and thus induces TP53 repression of BIRC5 promoter (By similarity).  May act as a corepressor of transcription factors (Potential).
What are the official names of this protein?
Homeodomain-interacting protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR7A_ECOLX
Sequence: MLTYLFCDPSISFVPIWVLVTITTGSPQANRRCCIMTPNISITLNTPHVTIERYSELTGLSIDTINDMLADGRIPRHRLRKDKKREKVMINLAALTVDALTDCNVVFN
What are the official names of this protein?
Protein ORFa in retron Ec67.
Protein: RPIA_XYLFA
Sequence: MSEAKRRAAEKAIEYVENDMIIGVGTGSTVAYFIDALGRTPKRIKGAVSSSEQSTAHLKQHGIEVLELNHTGTLPLYVDGADECDPYKRLIKGGGASLTREKIIAEASKQFICIIDPNKQVATLGKLPLPIEVIPMARSLVARQIMARTDGQPVWREGVITDNGNVILDVHHLRITDPVKLEQELNQIPGVVCVGLFARRCADLVIIGSEPPHIL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RBFA_STAAR
Sequence: MSSMRAERVGEQMKKELMDIINNKVKDPRVGFITITDVVLTNDLSQAKVFLTVLGNDKEVENTFKALDKAKGFIKSELGSRMRLRIMPELMYEYDQSIEYGNKIERMIQDLHKQDR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I84A4
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYIQMCTELKLSDNEGRLIQNSITIERMVLSAFDERRNRYLEEHPSAGRDPKKTGGPIYRRREGKWVRELVLYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGVNDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRSPGNAEIEDLIFLARSALILRGAVAHKSCLPACVHGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGARVLPRGQLSTRGVQIASNENMETMSSSTLELRSKYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNAEGRTSDMRTEIIRMMENARPEDVSFQGRGVFELSDEKATNPIVPSFDMSKEGSYFFGDNAEEFDS
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RPOB_GRABC
Sequence: MNAITQRDSKSFTGRKRIRKSFARIGDVVPMPNLIDVQRASYEAFLQMNVHPDNRTPTGLQEVFRSVFPIDDFAGRGRLEFVNYELEEPKYDVEECIQRGMTFAAPLKVILRLIVWDVDEDTGSRSIRDIKEQPVYMGDMPLMTDNGTFIINGTERVIVSQMHRSPGVFFDHDKGKTHSSGKFLFAARVIPYRGSWLDFEFDSKDLVYVRIDRRRKLPVTTLLYALEGQRTEAAIASGTDPQDLPEIHGMTAEEILSYFYTQVVFTSTPKGWARPFDPEAFRGITLAEALIDADTGTVVAEAGTKLTARSARKIAEQAKTVLVGRADLLGRYMAEDLVNDQTGEIYAEAGEELTEARLAALETLGVTSLPTLAVDQTTGPWIRNTLAIDKNSTRDDALIDIYRVMRPGEPPTPETAEALFRGLFFDMDRYDLSSVGRVKMNMRLGVDAPDTVRTLRKEDILRTVKILCDLKDGRGAIDDIDNLGNRRVRSVGELMENQYRLGLLRMERAIRERMGSVDIDTVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATYAKVNKYGFIETPYRMVEDGKVSDQWRYLSAMEEDRLVVAQADAPRDSTGKLTEELISVRRQGDFRLVKPEDVTSMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLIRADAPLVGTGMEAAVARDSGATIVARRAGVVDQIDGARIVVRASGEDGATQGVDIYRLRKFMRSNQSTCINQRPLVKVGDHVISGDIIADGPSTELGELALGRNVLCAFMPWNGYNFEDSILISERIARDDVFTSIHIEEFEVMARDTKLGQEEITRDIPNVGEEALRNLDEAGIVYIGAEVNPGDILVGKVTPKGESPMTPEEKLLRAIFGEKASDVRDTSLKLPPGTTGTIVDVRVFSRRGVDKDERAMAIERAEIERLAKDRDDERGIQERAFLNRLREKLMGHPASGGFKGIKAGTIITDEVLAEHPRGAWRNISVQDDAVVADIELLKREFDAAVAKIQARFEGKVEKLQRGDELPPGVMKMVKVFVAVKRKLQPGDKMAGRHGNKGVVSRVVPVEDMPFLEDGTPVDLVLNPLGVPSRMNVGQILETHLGWACANLGRQIGELVEDYRRNGQQRDELLSRLREIYGENVYNDVIADMNNDQLIELAENLRKGVPIATPVFDGARPSDIENMLSRAGLDTSGQVVLTDGRTGEPFERKVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVSGRTKVYEAIVRDQDSFEAGIPESFNVLMKELKSLGLNVDLENRSA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TM216_BOVIN
Sequence: MAPRGKRLSSTPLEILFFLNGWYYATYFLLELFIFLYKGLLLPYPTANLVLDVVMLFLYLGVEVIRLFFGTKGNLCQRKMPLGISVALTFPSTMMASYYLLLQTYVLRLEAIMNSILLFFCGSELLLEVLTLTAFSSMDRM
What is the function of this protein?
Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition.
What are the official names of this protein?
Transmembrane protein 216.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: PTPRK_MOUSE
Sequence: MDVAAAALPAFVALWLLYPWPLLGSALGQFSAGGCTFDDGPGACDYHQDLYDDFEWVHVSAQEPHYLPPEMPQGSYMVVDSSNHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNPGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIATGRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRGHNESRADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLEPNGIITQYEVSYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPSLPDYEGVDASLNETATTITVLLRPAQAKGAPISAYQIVVEQLHPHRTKREAGAMECYQVPVTYQNALSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYKGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAAATEEPEVIPDPAKQTDRVVKIAGISAGILVFILLLLVVIVIVKKSKLAKKRKDAMGNTRQEMTHMVNAMDRSYADQSTLHAEDPLSLTFMDQHNFSPRLPNDPLVPTAVLDENHSATAESSRLLDVPRYLCEGTESPYQTGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQGPVHETVYDFWRMVWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS
What is the function of this protein?
Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis.  Negative regulator of EGFR signaling pathway.  Forms complexes with beta-catenin and gamma-catenin/plakoglobin.  Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa.
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase kappa, Protein-tyrosine phosphatase kappa, R-PTP-kappa.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: YE3O_CAEEL
Sequence: MSNVDRYDVHRDGIEKDRKRSRSRKPHQNGQSQSTMDNRPPWNNDTYIEGYDDVDEHGKFRKRGGGMPKTIDRQQEELTKNWTESLREQHHQPQKQ
What are the official names of this protein?
Uncharacterized protein C41G7.7.
Protein: SYT_BUCAP
Sequence: MPVIRFCDGSQQVYKHSVSLREIIENKKPNIIRSLIAISVNNSFSNFNTLITEDSSISFISKKDCEALNIIRYSCIQLLNYAAKKTWPSCKIGESEITKSGFYCDIDFENSITEEDFFILENNMKTLIKREYFISHQNISFDHAYEMFKKKSEIYKIHLIKKYINKKNKISLYYHENYFDIDMGMQVFNIKFCKYFKLQKIGGIYWKGDHKNKMLQRIYGTAWSTKKELDKHLSYINELKKRDHRKIGKLLNLYHMQKESPGMIFWHNNGWIIFNELEIFVREKLKEYKYKEVKTPLLIDKSIWQKSGHWDNYQDAIFTTSSENREYCIKPMNCPGHVQIFNCGLKSYRDLPIRMAEFGSCHRNESSGSLHGLMRIRNFTQDDAHIFCTQEQLRYEINNCIKMIYDLYSTFNFKKILVKFSTRPKKRIGDESVWDQAEKDLSDVLIENNLKFEHQEGEGAFYGPKIEFVLQDSLDRNWQCGTIQLDFYLPIRLRSFYIDEHNHQKIPIIIHRAILGSIERFIGILIEEFSGKLPTWLSPIQVVILSITDSHINYVKKIVQHFSDINIRVESDLRNEKIGFKIREHTLRQIPYILICGEKEIKSKKISVRTRNGYNLGIIDIDCFIKKLQKEIFTRSFYQMEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_STRTD
Sequence: MIQQESRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVATVKQATPGGAVKKGDVVKAVIVRTKTGARRSDGSYIKFDDNAAVIIRDDKTPRGTRIFGPVARELREGGYMRIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: VATD_CHLPN
Sequence: MSVQVKLTKNSFRLEKQKLARLQTYLPTLKLKKALLQAEVQNAVKDAAECDKDYVQAYERIYAFAELFSIPLCTDCVEKSFEIQSIDNDFENIAGVEVPIVREVTLFPASYSLLGTPIWLDTMLSASKELVVKKVMAEVSKERLKILEEELRAVSIRVNLFEKKLIPETTKILKKIAVFLSDRSITDVGQVKMAKKKIELRKARGDECV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: SDC2_RAT
Sequence: MQRAWILLTLGLMACVSAETRAELTSDKDMYLDSSSIEEASGLYPIDDDDYSSASGSGAYEDKGSPDLTTSQLIPRISLTSAAPEVETMTLKTQSITPTQTESPEETDKKEFEISEAEEKQDPAVKSTDVYTEKHSDNLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA
What is the function of this protein?
Cell surface proteoglycan which regulates dendritic arbor morphogenesis.
What are the official names of this protein?
Syndecan-2, SYND2, Fibroglycan, Heparan sulfate proteoglycan core protein, HSPG.
What is the protein family that this protein belongs to?
Belongs to the syndecan proteoglycan family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.