PharMolix/UniProtQA huggingface dataset:
Protein: SODC_XIPGL
Sequence: MVLKAVCVLRGAGETTGTVYFEQEGNANAVGKGIILKGLTPGEHGFHVHGFGDNTNGCISAGPHFNPASKKHAGPKDEDRHVGDLGNVTADANGVAKIDITDKISLTGPYSIIGRTMVIHEKADDLGRGGNEESLKTGNAGSRLACGVIGTE
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: REV_HV1H2
Sequence: MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: METN_CHLFF
Sequence: MLEKNPVISVKNLNKEIGNHRILNDISFSVCSGEILGIIGHSGSGKSTLLRCLDFLISPTSGSISIAGFHNSSAKEKISRSDFAKRVAYISQNGGLFLAKTVFENIAYPLKIRYPEMTKSLIEEKVNEALHFLNLYERKHAYPSRLSGGQKQKAAIAIAIVSDPQVLLCDEITSALDPRSTEDITDKLLQLNEERGITQVFVSHEIEVIKKLCTHTLVMHQGNIEELGPADKLFLNPYSSITEELFHMNSIAKGIYDHNENEEILRLGFPKGLAVQGMISQLIQGGQISINILSGDINLFRKIPLGFLIIVLSGEKKLRDRAKDILIGKGVIVQKFQKSR
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRPE_NEIMF
Sequence: MISKQEYQAQAAQGYNRIPLVQELLADLDTPLSLYLKLANRPYTYLLESVVGGERFGRYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHDGNPLPFIEAFHNRFKTPEIPSLPRFTGGLVGYFGYETIYNFEHFAHRLKNTTKADPLGTPDILLMLSQELAVVDNLSGKIYLIVYADPSQPDGYERARERLEDIRTQLRQSCAIPLSLGSKHTEAVSEFGEEPFKACVNKIKDYIFAGDCMQVVPSQRMSMEFTDSSLALYRALRTLNPSPYLFYYDFGDFHIVGSSPEILVRRERDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKEIAEHVMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGRLKDGMTNMDILAATFPAGTLSGAPKVRAMEIIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTLYVQSGAGVVADSDPASEWQETQNKARAVIHAAQMVQEGLDK
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: L_RABVP
Sequence: MLDPGEVYDDPIDPIELEAEPRGTPTVPNILRNSDYNLNSPLIEDPARLMLEWLKTGNRPYRMTLTDNCSRSFRVLKDYFKKVDLGSLKVGGMAAQSMISLWLYGAHSESNRSRRCITDLAHFYSKSSPIEKLLNLTLGNRGLRIPPEGVLSCLERVDYDNAFGRYLANTYSSYLFFHVITLYMNALDWDEEKTILALWKDLTSVDIGKDLVKFKDQIWGLLIVTKDFVYSQSSNCLFDRNYTLMLKDLFLSRFNSLMVLLSPPEPRYSDDLISQLCQLYIAGDQVLSMCGNSGYEVIKILEPYVVNSLVQRAEKFRPLIHSLGDFPVFIKDKVSQLEETFGSCARRFFRALDQFDNIHDLVFVYGCYRHWGHPYIDYRKGLSKLYDQVHIKKVIDKSYQECLASDLARRILRWGFDKYSKWYLDSRFLARDHPLTPYIKTQTWPPKHIVDLVGDTWHKLPITQIFEIPESMDPSEILDDKSHSFTRTRLASWLSENRGGPVPSEKVIITALSKPPVNPREFLKSIDLGGLPDEDLIIGLKPKERELKIEGRFFALMSWNLRLYFVITEKLLANYILPLFDALTMTDNLNKVFKKLIDRVTGQGLLDYSRVTYAFHLDYEKWNNHQRLESTEDVFSVLDQVFGLKRVFSRTHEFFQKSWIYYSDRSDLIGLREDQIYCLDASNGPTCWNGQDGGLEGLRQKGWSLVSLLMIDRESQIRNTRTKVLAQGDNQVLCPTYMLSPGLSQEGLLYELESISRNAFSIYRAVEEGASKLGLIIKKEETMCSYDFLIYGKTPLFRGNILVPESKRWARVSCVSNDQIVNLANIMSTVSTNALTVAQHSQSLIKPMRDFLLMSVQAVFHYLLFSPILKGRVYKILSAEGESFLLAMSRIIYLDPSLGGVSGMSLGRFHIRQFSDPVSEGLSFWREIWLSSHESWIHALCQEAGNPDLGERTLESFTRLLEDPTTLNIRGGASPTILLKDAIRKALYDEVDKVENSEFREAILLSKTHRDNFILFLTSVEPLFPRFLSELFSSSFLGIPESIIGLIQNSRTIRRQFRKSLSKTLEESFYNSEIHGISRMTQTPQRVGGVWPCSSERADLLREISWGRKVVGTTVPHPSEMLGLLPKSSISCTCGATGGGNPRVSVSVLPSFDQSFFCTGPLKGYLGSSTSMSTQLFHAWEKVTNVHVVKRALSLKESINWFITRDSNLAQTLIRNIVSLTGPDFPLEEAPVFKRTGSALHRFKSARYSEGGYSSVCPNLLSHISVSTDTMSDLTQDGKNYDFMFQPLMLYAQTWTSELVQRDTRLRDSTFHWHLQCNRCVRPIDDVTLETSQIFEFPDVSKRISRMVSGAVPHFQRLPDIRLRPGDFESLSGREKSHHIGSAQGLLYSILVAIHDSGYNDGTIFPVNIYGKVSPRDYLRGLARGVLIGSSICFLTRMTNININRPLELISGVISYILLRLDNHPSLYIMLREPSFREEIFSIPQKIPAAYPTTMKEGNRSILCYLQHVLRYEREVITASPENDWLWIFSDFRSAKMTYLTLITYQSHLLLQRVERNLSKSMRDNLRQLSSLMRQVLGGHGEDTLESDDNIQRLLKDSLRRTRWVDQEVRHAARTMTGDYSPNKKVSRKVGCSEWVCSAQQVAVSTSANPAPVSELDIRALSKRFQNPLISGLRVVQWATGAHYKLKPILDDLNVFPSLCLVVGDGSGGISRAVLNMFPDAKLVFNSLLEVNDLMASGTHPLPPSAIMRGGNDIVSRVIDFDSIWEKPSDLRNLATWKYFQSVQKQVNMSYDLIICDAEVTDIASINRITLLMSDFALSIDGPLYLVFKTYGTMLVNPNYKAIQHLSRAFPSVTGFITQVTSSFSSELYLRFSKRGKFFRDAEYLTSSTLREMSLVLFNCSSPKSEMQRARSLNYQDLVRGFPEEIISNPYNEMIITLIDSDVESFLVHKMVDDLELQRGTLSKVAIIIAIMIVFSNRVFNVSKPLTDPLFYPPSDPKILRHFNICCSTMMYLSTALGDVPSFARLHDLYNRPITYYFRKQVILGNVYLSWSWSNDTSVFKRVACNSSLSLSSHWIRLIYKIVKTTRLVGSIKDLSGEVERHLHRYNRWITLENIRSRSSLLDYSCLCIGYSWKPAHAKTLV
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
Large structural protein, Protein L, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the rhabdoviruses protein L family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=L and P are packaged asymmetrically towards the blunt end of the virus.
Protein: CA1D_CONRE
Sequence: GCCSDPRCKHEC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like Reg1d.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RSLAA_HUMAN
Sequence: MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
What is the function of this protein?
Potent inhibitor of cellular proliferation.
What are the official names of this protein?
Ras-like protein family member 10A, Ras-like protein RRP22, Ras-related protein on chromosome 22.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Nucleus, nucleolus. Note=May cycle in and out of the nucleolus in a GTP-dependent manner.
Protein: RS9_ACISJ
Sequence: MIGEWNNGTGRRKSSVARVFLKKGSGKITVNGKDIQQYFGRETSIMIAKQPLALTNHVETFDIQINVHGGGESGQAGAARHGITRALIDYDATLKPALSQAGFVTRDAREVERKKVGLHSARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: EXT1_DROME
Sequence: MQAKKRYILVFVSCAFLAYAYFGGYRLKVSPLRPRRAQHESAKDGGVQPHEQLPSFLGAHDMQELQLLQSNQSKSLDSSKHLVTRKPDCRMETCFDFTRCYDRFLVYIYPPEPLNSLGAAPPTSANYQKILTAIQESRYYTSDPTAACLFVLGIDTLDRDSLSEDYVRNVPSRLARLPYWNNGRNHIIFNLYSGTWPDYAENSLGFDAGEAILAKASMGVLQLRHGFDVSIPLFHKQFPLRAGATGTVQSNNFPANKKYLLAFKGKRYVHGIGSETRNSLFHLHNGRDMVLVTTCRHGKSWRELQDNRCDEDNREYDRYDYETLLQNSTFCLVPRGRRLGSFRFLEALQAGCIPVLLSNAWVLPFESKIDWKQAAIWADERLLLQVPDIVRSIPAERIFALRQQTQVLWERYFGSIEKIVFTTFEIIRERLPDYPVRSSLVWNSSPGALLTLPTFADSSRYMPFLLNSMGAEPRHNYTAVIYVQIGAALGPNAALYKLVRTITKSQFVERILVLWAADRPLPLKKRWPPTSHIPLHVISLGGSTRSQGAGPTSQTTEGRPSISQRFLPYDEIQTDAVLSLDEDAILNTDELDFAYTVWRDFPERIVGYPARAHFWDDSKNAWGYTSKWTNYYSIVLTGAAFYHRYYNYLYTNWLSLLLLKTVQQSSNCEDILMNLLVSHVTRKPPIKVTQRKGYKDRETGRSPWNDPDHFIQRQSCLNTFAAVFGYMPLIRSNLRMDPMLYRDPVSNLRKKYRQIELVGS
What is the function of this protein?
Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.  Botv is the trigger of heparan sulfate chain initiation and polymerization takes place by a complex of ttv and sotv.  Plays a central role in the diffusion of morphogens hedgehog (hh), wingless (wg) and decapentaplegic (dpp) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis which are required for movement of hh, dpp and wg morphogens.
What are the official names of this protein?
Exostosin-1, Protein tout-velu, TTV.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Localization to the Golgi may be regulated by sau (PubMed:23720043).
Protein: RECR_SYNE7
Sequence: MSVYTRPLARLIEHLQKLPGVGPKTAQRLALHLIQRPEAEIAAFAEALLAAKQQVGHCQRCFHLSSEDLCNICRDPKRDAQTICVVADPRDVIALEKTREYKGLYHVLGGLISPMDGIGPEQLTVQALVRRVAQEQTQEVIMAISPSVEGETTTLYVGQLLKPFTRVTRIAFGLPMGGDLEYADEVTLARALEGRRDLT
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: STXB1_HUMAN
Sequence: MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS
What is the function of this protein?
Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity).  Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio.  Can interact with syntaxins 1, 2, and 3 but not syntaxin 4.  Involved in the release of neurotransmitters from neurons through interacting with SNARE complex component STX1A and mediating the assembly of the SNARE complex at synapic membranes (By similarity).  May play a role in determining the specificity of intracellular fusion reactions.
What are the official names of this protein?
Syntaxin-binding protein 1, MUNC18-1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
Protein: RIBA_ECO81
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTEAGINIIERVPLIVGRNPNNEHYLDTKAEKMGHLLNK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: PLSB_PSEPG
Sequence: MTRSPLHRLIFGGLRRLLYLWVRSETINQSSMTLNLDRSRPVFYALPSPSLTDLAVLDHECTKAGLPRPVLPVAVGPLQEPAAFFYLTPDPDWLGRQDKSGAPPTLERLVAAVSQHAEEDAQIIPVSVFWGQTPASESSPWKLLFADSWAVTGRLRRLLTVLILGRKTRVQFSAPIHLRELVQHNKGHARTVRMAQRLMRVHFRNLKTAVIGPDISHRRNLVKGLVHAPLVRQAIADEAQRENLPLAKAEAQALRYGNEIASDYTYTVIRFLEVVLSWFWNKIYDGIKVNHIEQVQGIAPGHEVIYVPCHRSHIDYLLLSYLLFRNGLTPPHVAAGINLNMPVVGNLLRRGGAFFMRRTFKGNPLYTAVFNEYLHTLYTKGFPVEYFVEGGRSRTGRMLQPRTGMLAITLRSFLRSSRTPIVFVPVYIGYERVLEGRTYLGELRGASKKKESVLDIFKVFGALKQRFGQVYVNFGEPIRLAGFLDQQQPGWREQDHGPQYRPDWLNATTTRLGETVARHLNEAAAINPVNLVALALLSTSRLALDERALTRVLDLYLALLRQVPYSPHTTLPDGDGQALIEHVRSMNLVAEQKDALGRILFLDEGNAVLMTYYRNNVLHIFALPALLASFFLSSSRMSRELLGQYVHALYPYLQAELFLRWAPEQLDEVIDQWLAALVEQGLLRQENDVYVRPAPSSRQFVLLTLLARTITQTLQRFYMATSLLINSGQNSLSAEALEDLCVMMAQRLSILHGLNAPEFFDKTLFRHFIQTLLQQGVLHTDTQGKLGYHDKLGELAEGVAKRVLSAELRLSIRQVALHRDDGLESSTI
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL18_METVS
Sequence: MAQNAKHRVPFRRRREGKTDFRQRLGLLLSGKPRLVARKSLNNIIAQLMAYDEKGDIVLVSAHSRELVKMGYKGHCGNLPAAYLTGLLLGKKAVEEGLEEAILDKGLHRATKGAAIFAVLKGALDAGMDIPCGEEIIADEERLNGTHIKQYAELLKEDEEAYKKQFSKYLEKGLNPEDLPEHFEELKGKILNL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: Y2281_CALBD
Sequence: MPRPIRCRRVEFLPRFNYFSPREGSNDEVQLKVEELEAIRLKDLEGLMQEECAQKMQVSRQTFQLILEEARKKVADALVNGKAIRIEGGNYVFGNCKYTCLNCGKVFELDKDECPECHSSQVVCHRGKGRGHCFRHHRGW
What are the official names of this protein?
UPF0251 protein Athe_2281.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: ARGAL_BOVIN
Sequence: MASSSPLQAAAGDRLLPGGPGPSPEAEDDPGEGFEFDDSDDDEDTNAGPDVPRSALETEADTPLIHLDSAPVIDLEPKPEPAQPQTQRPAAVSNGDAVDAAFSEVQRSGWRRKSSRRIERFTFPAVEEDVIYDDVPCENLDAQQPEAERNQPYEDARQDRAPQEPEDLGWSSSEFESYSEDSGEEAKPEAEPTKHRVSFQPKMTQLMKAAKSGTKDGLEKTRIAVMRKVSFLHRKDVLGDSEEEDMGLLEVSVSDIKPPAPELGPMPAGLTPQQVVRRHILGSIVQSEGSYVDSLKRVLQDYRNPLMEMEPKALSARKCRAVFFRVKEILHCHSMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTNAMSIIKKACLTKPAFLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTELETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLTSGQRQLLLCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKGQLEISSLAPLGPKYVVKWSTALPQVQVVEVGQEGGPYDKDNALIQHAGAKKASAAGQAQNKVYLGPPRLFQELQDLQKDLAVVEQITLLVSTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKQSRAPFWCPILACCVPAFSFRGLSLQLGALVHSPVSCPLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRPSPRTVKSFPLAAPVLCMEYIPEPEEGDGRNGDKGCPAADASAGVHPTICLGLQDGSILLYSSVDTGTQCLAACRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGSVPWDLESPPMCLPVGPGPVRALLSLEEAVWASCGPRVTVLDATSLQTQQSFEAHQDEAVSVTHMVKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFLLPGQKHLCVTSLLICQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFLAVATSILAPDILRSDQEEAEGQQAEEDKPDGPAPEPAPVPASHVGGELIRKKGILLQYRLRSTSHLPGPLLSVREPEPADGSALEHSEEDGSIYEMVDDPDVWVHNRPCARDAHRKEICSVAIISGGRGYRNFGSAAGSPGKPAPCGETDSTLLIWQAPLTL
What is the function of this protein?
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 10-like protein, GrinchGEF.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTE_VIBC3
Sequence: MTKSLFRQSFLFDSLDLDHPMVAQTVRTEQGVTLKLHQRGVLEVIPAQTDAATKNMVISCGVHGDETAPMELLDKWIDDIVSGFQPVAERCLFILAHPQATVRHVRFIEQNLNRLFDDKPHTPSTELAIADNLKVLLKQFFANTDEHSRWHLDLHCAIRGSKHYSFAVSPKARHPVRSRSLMQFIEQAHIEAVMLSNAPSSTFSWYSAEHYAAQALTLELGQVARLGENLLDRLLAFDLAMRDLISRHKPEHLPRKSVMYRVSRTIVRLHDDFDFRFSDDVENFTAFMHGEVFGHDGDKPLMAKNEGEAIVFPNRKVAIGQRAALMVCKVNTRYEDDQLVYD
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: SCPA_DESHY
Sequence: MSNGSSVSHSANTAPYVELPAFQGPMDLLLHLIQQEKVDIYDIPIARITDQFIQVVRQMEDLDMEVTTEFLVLAAQLLQIKSRYLLPKPVKDVTVEEEGDPRQELVERLLAYRAFKQAAETLGEIQISSGQRYFREVDVDGLRSQFTPADPLAGIHFEALWHAFQRIIERAEQGEEIRTVEPDEIPIEVMVNDVLRRVILHPRGLRFSQLIRGTKRMEIIVSFLALLELLKSGKVHCEQSSQNEEIFVFPTEKAWEFTEGE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: Y996_STAA8
Sequence: MSRKTYEKIANINGMFNMLEQQIIHSQDMAHFRSEFFYVNHEHRENYEALLIYYKNSIDNPIVDGACYILALPEIFNSVDVFESELPFSWVYDENGITETMKSLSIPLQYLVAAALEVTDVNIFKPSGFTMGMNNWNIAQMRIFWQYTAIIRKEAL
What are the official names of this protein?
Uncharacterized protein SAOUHSC_00996, ORF2.
Protein: AROA_ECOL6
Sequence: MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAESARELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIRGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKESDRLFAMATELRKVGAEVEEGHDFIRITPPEKLKFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQPG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PT494_SACBA
Sequence: MHLKKGKRSIGTVWRLLWKRLYSVHYKTNTYSTRSRKKLVTNFTRVNGLLLSCNGDTFPYMRTLWRYFNAPGNLMFVTTNIITFTGIVAYNTMVTVSNERVFEEQMIAAQMSLAKQKEELETRALDFPANHEQIKEADDANCEQPAIERSGEDRSVKQQNEQLDSPIRHYSLTDLVLNKEARVADYDSQRVKASLFHMLYAYMLYRDTIQPNSDSPNHNSEEWRHEVELLTRDKWLQGAHQRIDVFYDLWNNQLDKIVTSPEKVQNFHLPNWSKYPTLLKFICTELHNNELTTLDEFKQFYGKVRSNEVKKLLGLWLYDHSFLFPRNIYDNKNQEVFYDTLISDSMQDNKIFQKYSSIVMNPDNERTQLFFPNIYAQPVNKPIPSISLETYTRLLRGYITLQETNCKYDYNDNIFKLISILKMNCFLQHDKKIRTGASVRILLPRDEDRSPVLNTIPQAEKKTCYQILSKNRDILALLKRISDIQIDSS
What is the function of this protein?
Required for the expression of the mitochondrial gene for cytochrome c oxidase subunit III (COX3).
What are the official names of this protein?
COX3 mRNA-specific translational activator PET494.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: RRP31_ARATH
Sequence: MMSSMALSSTSLCSSFISQHPKLSITASPPLFHTQTTKPISVKRKIITLAAPETLTAETVTGIDTSDNTPQQTIKVVKPDEKSRVVLKFVWMEKNIGLGLDQHVPGHGTIPLSPYFFWPRKDAWEELKSTLEAKPWISQKKMIILLNQATDIINLWQQSGGNLTSQ
What is the function of this protein?
Probably a ribosomal protein or a ribosome-associated protein.
What are the official names of this protein?
30S ribosomal protein 3-1, chloroplastic, Plastid-specific 30S ribosomal protein 3-1, PSRP-3 1.
What is the protein family that this protein belongs to?
Belongs to the chloroplast-specific ribosomal protein cS23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LYETB_XENLA
Sequence: MMNFRQRMGWIGVSLYLFVSAAAFYYVFEINETYNRLALEHVQLKPHEPHRGTTWTHSLKIRLLSLPFWLWAALFLIPYFQVFLFLYSCTRADPKTVGYCIIPICLAIICNRHQSFVKASNRISKLQLIDT
What is the function of this protein?
Required for mannose-6-phosphate-dependent trafficking of lysosomal enzymes.  LYSET bridges GlcNAc-1-phosphate transferase (GNPTAB), to the membrane-bound transcription factor site-1 protease (MBTPS1), thus allowing proteolytic activation of the GNPTAB.  GNPTAB is involved in the regulation of M6P-dependent Golgi-to-lysosome trafficking of lysosomal enzymes.  LYSET is thus an essential factor for maturation and delivery of lysosomal hydrolases.
What are the official names of this protein?
Lysosomal enzyme trafficking factor, Transmembrane protein 251, Transmembrane protein 251-B.
What is the protein family that this protein belongs to?
Belongs to the LYSET family.