PharMolix/UniProtQA huggingface dataset:
Protein: GRP2_ORYSI
Sequence: MATTKHLALAILVLLSIGMTTSARTLLGYGPGGGGGGGGGGEGGGGGYGGSGYGSGSGYGEGGGSGGAAGGGYGRGGGGGGGGGEGGGSGSGYGSGQGSGYGAGVGGAGGYGSGGGGGGGQGGGAGGYGQGSGYGSGYGSGAGGAHGGGYGSGGGGGGGGGQGGGSGSGSGSGYGSGSGGGNGHH
What is the function of this protein?
Responsible for plasticity of the cell wall.
What are the official names of this protein?
Glycine-rich cell wall structural protein 2, Glycine-rich protein 1, GRP-1.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: BOMB_BOMBO
Sequence: QQRLGNQWAVGHLM
What is the function of this protein?
Stimulates smooth muscle contraction.  Role in induction of hypothermia, stimulation of DNA replication and release of many gastrointestinal hormones (By similarity).
What are the official names of this protein?
Bombesin.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CIAO1_DROVI
Sequence: MVRLILEHTLQGHKGRIWGVAWHPKGNSFASCGEDKAIRIWSLSGNTWTTKTILSDGHKRTIREVRWSPCGEYLASASFDATTAIWSKHECTATLEGHENEVKSVSWSRSGGLLATCSRDKSVWIWEVAGDDEFECAAVLNAHSQDVKRVVWHPTKEVLASASYDNTIKMFAESALDSDWDCTATLSSHTSTVWSIDFDADGERLVSCSDDATLKIWRAYHPGNDAGIATPDKTTVWKCVCTLSGEHSRAIYDVSWCKQTGLIASACGDDGIRIFKECSDSKRDAPTFELLTAEESAHEQDVNAVEWNPVTAGQLISCSDDGTIKIWKLQE
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein Ciao1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
Protein: RS6_PSEA8
Sequence: MRHYEIVFLVHPDQSEQVGGMVERYTKAIEEDGGKIHRLEDWGRRQLAYAINNVHKAHYVLMNVECSAKALAELEDNFRYNDAVIRNLVMRRDEAVTEQSEMLKAEESRNERRERRERPNDNAEGADGDDNSDSDNADE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: UBP2_DROME
Sequence: MMLDIKKTRGFHKIPQASKLQSTTKTSSVVATSASSQNEVPSPGGSAGSKVGATNPVRAANQRFFLVSSYKDPTFLKAECDLAHAHVTTSKVKTTLQPHRRSRAGEDSRNNNYNTSRAPTLINMRRPSLFNGNQQPTTTNSTTINNTTSRNTTSNTSNGVLKYSVRSTTATATSTSTRNYGKLKPLNNNQTTAGVAMMNGHTNNNNNNTRNSSNINNGGNNNMQRQQQQHDDISFIDSDDPPATGGPEAGISTTKTSICYFKPITPPLQLRHEQNQVQQQEEQPQPSSSKSASHRYPRPKSTIIASAHSNFAASFEKFSGGLYRQTNGETNIESKTSSNARRYGIDSLSIKASIEKFNNLSGQKRQNPGSGSGIGPGSATASGLGGGRLSVASRSNHGSQAGGSSSNLQQRYSSDLDNIRVAAGYSSSLTRAAYRTTATMNSVSTPVAVTSELGGPISGDGGETATAMGQPTSKVTVRGAHSNRQPIECDSVVLTNKASKDATTAATPTVATATATHTPATSSVSTVTVTAAAPNSASDSTLARSGTGSSSTARSVLPPMTPTSSRYWDRDSGTSRSSIGTSSALNSSSLKHNSDDGYKTASSSRDEKSEGLCGLRNIGNTCFMNSVIQCLSHTQELTRFLRSHHGSRSLSTKDQQILHEFAKLIQEMWTANVHTVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGETLNIDDNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLPSSSRCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFSETRWSKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDALSENHLVSSSAYILFYERT
What is the function of this protein?
Required for preventing the activation of the immune deficiency (Imd) signaling cascade under unchallenged conditions.  Regulates the Imd pathway by specifically removing 'Lys-48'-linked ubiquitin from imd.  Also promotes imd degradation probably by binding to imd and enhancing its association with the proteasome.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase Usp2, Ubiquitin specific protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: AMPN_ACEPA
Sequence: MRRLLTLTTLLAGVPLAAPVCAEQVFSFQRAAGQLPKTVVPVSYGINISTDIDNLKLTGQETIQVDVRTPTEDVTLNQAGLHLAGAVLDNGVKATITQDDAAETATLHFPAKVSKGAHTLVITYSGPILKTPNGIYVDDYTAPSGETKRMLVTQFEVADARRMFPGWDEPAFKATFQLNVTLPKEAVAVSNMPVTQSTPEGTSQKRVSFATTPRMSTYLLALVAGDMKSVQGQADGTPLAVYAPSGLEEQGEYALHASEKILPYYNNYFGVKYPLPQMDMVAIPGNYQAGAMENWGLLTYIDNVLLFDPPNSTPRTRELIYEVVAHEMAHQWSGDLVTMGWWDNIWLNEGFASWM
What is the function of this protein?
Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.
What are the official names of this protein?
Aminopeptidase N, Alpha-aminoacylpeptide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIA_SPIOL
Sequence: MAASVDRQYHPAPMSGVVRTPFSNHHRSDSPVRNGYTFSNPPSSNGVVKPGEKIKLVDNNSNSNNGSNNNNNRYDSDSEEDDDENEMNVWNEMIKKGNSELEPSSVDSRDEGTADQWIERNPSMIRLTGKHPFNSEPPLTRLMHHGFLTPVPLHYVRNHGPVPNAKWEDWTVEVTGLVKRPIRFTMDQLVNDFQSREFPVTLVCAGNRRKEQNMTKQSIGFNWGSAAVSTSVWRGVPLRDVLKRCGVMSSLKGALNVCFEGAEDLPGGGGSKYGTSVKREFAMDPARDIILAYMQNGEKLSPDHGYPVRMIIPGFIGGRMVKWLKRIIVTTTESDNYYHYKDNRVLPSHVDAELANSEAWWYKQEYIINELNVNSVITSPCHEEILPINAWTTQRPYTMRGYAYSGGGRKVTRVEVTMDGGDTWDICELDHQERGSKYGKFWCWCFWSLEVEVLDLLGAKEIGVRAWDESLNTQPEKLIWNVMGMMNNCWFRVKTNVCKPHKGEIGIVFEHPTQPGNKSGGWMARERHLEISDSGPTLKRTASTPFMNTTSKMYSMSEVKKHNTADSAWIVVHGNVYNATRFLKDHPGGSDSILINAGTDCTEEFDAIHSDKAKRLLEDFRIGELISTGYTSDSSSPGNSVHGGSVYSGLAGLAPITEAVPLRNVALNPRVKIPCKLIEKVSLSHDVRRFRFGLPSEDQVLGLPVGKHIFLCANVDDKLCMRAYTPSSTIDVVGYFDLVVKVYFKDVHPRFPNGGVMSQHLDSLSLGSIVDVKGPLGHIEYLGKGNFTVHGKPKFAKKLAMISGGTGITPIYQVMQAILKDPEDKTEMHVVYANRTEEDILLREELDKWADEFRDRVKVWYVVEKAEEGWKYDTGFISEKILRDHVPAVGDDVLALTCGPPPMIQFAVQPNLDKMGFDIKEQLLIF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADH], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: PCR7_ARATH
Sequence: MEKQWTSGLFSCMEDSETACLTCFCPCVTFGRIADISDEGRTGCGRCGVFYGLICCVVGLPCLFSCTYRTKIRSKFGLPESPTSDCVTHFFCECCALCQEHRELKTRGLDPSIGWSGNMQRTMAPPMSQQMMG
What is the function of this protein?
May be involved in heavy metals transport.
What are the official names of this protein?
Protein PLANT CADMIUM RESISTANCE 7, AtPCR7.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IAN4_ARATH
Sequence: MAGLEDTTDLRLPSASEPIKNIVLVGRTGNGKSATGNSLIGKQVFRSETRATGVTMKCETCVAVTPCGTGINVIDTPGLFDLSVSAEYLSQEIINCLVLAEDGLHAVVLVLSVRTRISQEEEATLNTLQVIFGSQIIDYLVVLFTGGDELEANNMTLDDYLSKGCPEFLKTVLRLCGGRRILFDNRTTDEGKKVKQVQELLAHVAAIEKSTSGIPFTDEMHRKIQKEAETLREQQKEVESKDLAAAEIEKWKKHYQTEHDKNMNMMAEMLGNRLREDSERQEKMLLALRDNLEISQRQNKLNELTDNEPDLIHCGVSLRRMPCNML
What are the official names of this protein?
Immune-associated nucleotide-binding protein 4, AtIAN4, AIG1-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
Protein: HPRT_SHIFL
Sequence: MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLDE
What is the function of this protein?
Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate).  To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.
What are the official names of this protein?
Hypoxanthine phosphoribosyltransferase, HPRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDH2_ORYSJ
Sequence: MAMWRAPSAAGQLLGRALASTAAQTSAGSKKVVGVFYKGGEYADKNPNFVGCVDSALGIRGWLESKGHRYIVTDDKEGINCELEKHIEDAHVLITTPFHPAYITAERIKKAKNLELLLTAGVGSDHIDLPAAAAAGLTVAEITGSNTVSVAEDQLMRILLLLRNFLPGHHQIVNGEWNVAGIAHRTYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLMYHDRVKIDPELEKEIGAKYEEDLDAMLPKCDVVVINMPLTEKTRGMFNKERIAKMKKGVTIVNNARGAIMDTQAVADACASGHVAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHCSGTTIDGQLRYAAGVKDMLDRYFKGEDFPAQNYIVKAGQLASQYQ
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide.  Involved in the cell stress response.
What are the official names of this protein?
Formate dehydrogenase 2, mitochondrial, FDH 2, NAD-dependent formate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TPIS_MOUSE
Sequence: MAPTRKFFVGGNWKMNGRKKCLGELICTLNAANVPAGTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVSHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVNDGVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase, TIM, Methylglyoxal synthase, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYT_NOTSC
Sequence: MVHSQLPVVALLRLLCALLLLPSATMIPGGLSPRSVTDPDVQEAAEFAVQEYNALSANAYYYKQLRIVEAQSQVVAGAKYYLTMELMKTKCAKTTGKPKVYKEIQNCELPPKAQQEKLTCRFQVWSRPWLQKIELTKMSCN
What is the function of this protein?
Inhibits various C1 cysteine proteases including cathepsin L, papain and cathepsin B.  This protein has no toxic activity and its function in the venom is unknown.  It may play a role as a housekeeping or regulatory protein (By similarity).
What are the official names of this protein?
Cystatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL29_ECOHS
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLNEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: HISZ_BACVZ
Sequence: MFMFEKPHGMRDTLPGLYEAKKKVRSTLTDLIDKWGYQFMETPTLEFYETVGVQSAIEEQQLFKLLDQDGKTLVLRPDMTGPIARVAASKLHKHNHPLRAGYAASVYRAQEREGGRPAEFEQVGAELIGDGSTSADAEVIALAAGALKNAGLHRFKIAIGHAGLADELFVEVLGNAERADVLRRFLFEKNYVGYREHVKSLPLSSIDKSRLLALLELRGGKEICAKAEEIIGISGQSLIQELEDLWDILEDYGCAEHIRLDLNMVSHMSYYTGILFEVYAANVGFVIGSGGRYNNLLGHFGSPAPATGFGLRIDRLIEALGIQEETSEADAVIFSKEQRAQAILFAEEERARGRKVVLQDLAGIENIDHMTKSFANVTYFIGARKEEQNG
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPA_LISMO
Sequence: MEQGTVKWFNAEKGFGFIERENGDDVFVHFSAIQGDGFKSLDEGQAVTFDVEEGQRGPQAANVQKA
What are the official names of this protein?
Cold shock-like protein CspLA, CspL.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXG_PHOLE
Sequence: MIFNCKVKKVEASDSHIYKVFIKPDKCFDFKAGQYVIVYLNGKNLPFSIANCPTCNELLELHVGGSVKESAIEAISHFINAFIYQKEFTIDAPHGDAWLRDESQSPLLLIAGGTGLSYINSILSCCISKQLSQPIYLYWGVNNCNLLYADQQLKTLAAQYRNINYIPVVENLNTDWQGKIGNVIDAVIEDFSDLSDFDIYVCGPFGMSRTAKDILISQKKANIGKMYSDAFSYT
What is the function of this protein?
Probable flavin reductase in the luminescent systems of different marine bacteria.
What are the official names of this protein?
Probable flavin reductase.
What is the protein family that this protein belongs to?
Belongs to the Fre/LuxG FAD/NAD(P) flavoprotein oxidoreductase family.
Protein: EFTS_CITBB
Sequence: MSITAAQVNELRKATGAGLMDCKKALTETGGDHEKAIDYLRTKGLAAASKKAGRAATEGLVGSYIHAGGKIGVLVEVNCETDFVAKNENFQGFVKDIAMHIAAASPLYVRREEVPAELIEREKAIYREKAKESGKPAAIIEKILDGQINKFFADICLLEQTYVKDPDKTIQTFLNETIASIGENMSIRRFAKFVLGEGLAKKESDFAAEVAAAVGQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYB44_ARATH
Sequence: MADRIKGPWSPEEDEQLRRLVVKYGPRNWTVISKSIPGRSGKSCRLRWCNQLSPQVEHRPFSAEEDETIARAHAQFGNKWATIARLLNGRTDNAVKNHWNSTLKRKCGGYDHRGYDGSEDHRPVKRSVSAGSPPVVTGLYMSPGSPTGSDVSDSSTIPILPSVELFKPVPRPGAVVLPLPIETSSSSDDPPTSLSLSLPGADVSEESNRSHESTNINNTTSSRHNHNNTVSFMPFSGGFRGAIEEMGKSFPGNGGEFMAVVQEMIKAEVRSYMTEMQRNNGGGFVGGFIDNGMIPMSQIGVGRIE
What is the function of this protein?
Transcription factor (PubMed:23067202, PubMed:23603962).  Represses the expression of protein phosphatases 2C in response to abscisic acid (ABA).  Confers resistance to abiotic stresses dependent of ABA (PubMed:18162593, PubMed:9678577).  In response to auxin, activates the transcription of the auxin-responsive gene IAA19.  The IAA19 transcription activation by MYB44 is enhanced by direct interaction between MYB44 and PYL8 (PubMed:24894996).  Transcriptional activator of WRKY70 by direct binding to its promoter region, especially at 5'-TAACNG-3' and 5'-CNGTTA-3' symmetric motifs (PubMed:23067202, PubMed:23603962).  Activates salicylic acid (SA)- mediated defenses and subsequent resistance to biotrophic pathogen P. syringae pv.  tomato DC3000, but represses jasmonic acid (JA)-mediated defenses responses against the necrotrophic pathogen A. brassicicola (PubMed:23067202).
What are the official names of this protein?
Transcription factor MYB44, Myb-related protein 44, AtMYB44, Myb-related protein R1, AtMYBR1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CALY_HUMAN
Sequence: MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPDQQNFPDLEGQRLNCSHPEEGRRLPTARMIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
What is the function of this protein?
Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
What are the official names of this protein?
Neuron-specific vesicular protein calcyon.
What is the protein family that this protein belongs to?
Belongs to the NSG family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.
Protein: RS16_GLUDA
Sequence: MSLKIRLARAGAKKRPYYHIVIADSRSPRDGRFIEKVGAYNPMLPSDHADRVRLVNERITHWLSQGALPTDRVARFLGNAGLAPKPAYTEQPKKSAPKKRAQERAAAAAAAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SRP19_HALWD
Sequence: MAVENIVWPRYLDASITRSDGRRVSLQDAIEDPEVDEIAEAVQQIGYDAVIEHDVAHPREWGTSGRVIVKGADDSSKNDLVQAVAAYIHLLRE
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_RHOPA
Sequence: MSVIDVNPIPLAPRISEAGVADYIALLKPRVMSLVVFTALVGLLMAPGSFHPVLAITAIICIAVGGGAAGALNMWYEDDIDAKMTRTANRPIPRGRVTRPEALTFGMTLAFFSVVTLGILVNWIAAGLLAFTIFFYVVIYTMWLKRWTAQNIVIGGAAGALPPVVAWASVTGSLAVEPILLFLIIFFWTPPHFWALALFRNDDYARAGVPMLPVVAGPDHTRLQILLYTVALVAVAAAPWPLGYFDVIYGVASLALGGWMLVLAVRVYRHRSGSAALRATRNLFKFSILYLFALFAILLVEVVAAAVLRLIG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMH_NEOSM
Sequence: MSVTGGSKDEILHKPVLLSEALKFLAPKNGGVYVDATFGAGGYTRAILSSVDCFVYAIDRDETVRRFFQVIENDFPKRTNFINGNFVDIGSLLGEVKVDGIVFDLGVSTMQLKVADRGFSFLHEGPLDMRMDRSTLLTAETVVNSYTEVKIASIIYQFGEERMSRKIAHAIVNARRKKRITTTSSLAEIVRSCFPKRYYKIDPATKTFQALRIFINDELGALECGLRTALTMLKVGSRAVVVSFHSLEDRIVKHLFRSVHGNGFNLLTKKIVVPSRDEVRENPSSRSARMRVIEKV
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_BACP2
Sequence: MAKDIKFSEEARRAMLRGVDALADAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPVGVRKGIEEAVKVALEGLHEISKPIEGKESIAQVASISAADEEVGSLIAEAMERVGNDGVITIEESKGFTTELEVVEGMQFDRGYASPYMVTDSDKMEAVLENPYILITDKKITNIQEILPVLEQVVQQGKPLLLIAEDVEGEALATLVVNKLRGTFNAVAVKAPGFGDRRKAMLEDISVLTGGELITEDLGLDLKSTEIGQLGRASKVVVTKENTTIVEGSGDSAQIAARVNQIRAQVEETTSEFDKEKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVSGGGTALVNVYKKVASIEADGDVQTGVNIVLRSLEEPIRQIAHNAGLEGSVIVERLKNEEIGVGFNAATNEWVNMIEKGIVDPTKVTRSALQNAASVAAMLLTTEAVVADKPEEGGSGGGMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSIE_SALCH
Sequence: MMPLSRSRLEFIATILQNVLNLGLLTLGLILVVFLGKETVHLADALFAPEQASKYELVEGLVIYFLYFEFIALIVKYFKSGLHFPLRYFVYIGITAIVRLIIVDHKTPMDVLLYSAAILLLVITLWLCNSNRLRRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPN1_HUMAN
Sequence: MAASAAAAELQASGGPRHPVCLLVLGMAGSGKTTFVQRLTGHLHAQGTPPYVINLDPAVHEVPFPANIDIRDTVKYKEVMKQYGLGPNGGIVTSLNLFATRFDQVMKFIEKAQNMSKYVLIDTPGQIEVFTWSASGTIITEALASSFPTVVIYVMDTSRSTNPVTFMSNMLYACSILYKTKLPFIVVMNKTDIIDHSFAVEWMQDFEAFQDALNQETTYVSNLTRSMSLVLDEFYSSLRVVGVSAVLGTGLDELFVQVTSAAEEYEREYRPEYERLKKSLANAESQQQREQLERLRKDMGSVALDAGTAKDSLSPVLHPSDLILTRGTLDEEDEEADSDTDDIDHRVTEESHEEPAFQNFMQESMAQYWKRNNK
What is the function of this protein?
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307).  May act at an RNAP assembly step prior to nuclear import (PubMed:21768307).  Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375).  May be involved in nuclear localization of XPA (PubMed:11058119).
What are the official names of this protein?
GPN-loop GTPase 1, MBD2-interacting protein, MBDin, RNAPII-associated protein 4, XPA-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: KHPA_OCEIH
Sequence: MKALIESIVASLVDYPEEIVINKTEEESKVVYHLTVHPDDVGKVIGKNGRIAKAIRTVVYASKTDGNKRIYLDIM
What is the function of this protein?
A probable RNA chaperone.  Forms a complex with KhpB which binds to cellular RNA and controls its expression.  Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
What are the official names of this protein?
RNA-binding protein KhpA, KH-domain protein A.
What is the protein family that this protein belongs to?
Belongs to the KhpA RNA-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBAP1_HUMAN
Sequence: MASKKLGADFHGTFSYLDDVPFKTGDKFKTPAKVGLPIGFSLPDCLQVVREVQYDFSLEKKTIEWAEEIKKIEEAEREAECKIAEAEAKVNSKSGPEGDSKMSFSKTHSTATMPPPINPILASLQHNSILTPTRVSSSATKQKVLSPPHIKADFNLADFECEEDPFDNLELKTIDEKEELRNILVGTTGPIMAQLLDNNLPRGGSGSVLQDEEVLASLERATLDFKPLHKPNGFITLPQLGNCEKMSLSSKVSLPPIPAVSNIKSLSFPKLDSDDSNQKTAKLASTFHSTSCLRNGTFQNSLKPSTQSSASELNGHHTLGLSALNLDSGTEMPALTSSQMPSLSVLSVCTEESSPPNTGPTVTPPNFSVSQVPNMPSCPQAYSELQMLSPSERQCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMHQCSEEKMMEFLQLMSKFKEMGFELKDIKEVLLLHNNDQDNALEDLMARAGAS
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process (PubMed:21757351, PubMed:22405001, PubMed:31203368).  Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) (PubMed:21757351, PubMed:22405001).  Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2 (PubMed:24284069, PubMed:22405001, PubMed:31203368).
What are the official names of this protein?
Ubiquitin-associated protein 1, UBAP-1, Nasopharyngeal carcinoma-associated gene 20 protein.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome. Note=Predominantly cytosolic (PubMed:21757351). Recruited to endosomes as part of the ESCRT-I complex (PubMed:21757351).
Protein: SNAA1_ARATH
Sequence: MFFVKGEGFFYPLFIELRNLIRYQTTRVSNSSRDFNLSQQHCSCFRPKRRHEAHLSFIGTLQYSKQRTITRAASATIARRQLLLLFDITFSSSSSCYYFQKKAEKKLNRRRRFDTKYEDAADLLEKARDSYKLAKSWDQAGIAYLKLADCHLKANSLANTYMIMDECMDHEIAEYYESDEMFEQAIAYYETAAEFFQIEEVTTSANQCNLKVAQYASQLEQQSRFMKTQARHSLNNKLLKYGVKGHLLTAGMCHLCKADVVSITNALEKYQDLDPTFSGTRECKFLADLASAIDEEDIAKFTDVSKEIDSVSPLVWAVNHMQLFGCKLCLVLDHDNNVVEGKREVQGQGAGGGCKLYLIEGKCILDWNNVYTKRIYNYTNF
What is the function of this protein?
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.  Binds to SNARE complex and then recruits NSF to disassemble it (By similarity).
What are the official names of this protein?
Alpha-soluble NSF attachment protein 1, Alpha-SNAP1, N-ethylmaleimide-sensitive factor attachment protein alpha 1.
What is the protein family that this protein belongs to?
Belongs to the SNAP family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.