PharMolix/UniProtQA huggingface dataset:
Protein: OMPA_RICCN
Sequence: MANISPKLFQKAIQQGLKAALFTTSTAAIMLSSSGALGIAVSGVIATNNNAAFSDNVGNNWNEITAAGVANGTPARGPQNNWAFTYGGDYTITADVADHIITAINVADTTPIGLNIAQNTVVGSIVTGGNLLPVTITAGKSLTLNGNNADAANHGFGAPADNYTGLGNIALGGANAALIIQSAAPAKITLAGNINGGGIITVKTDAAINGTIGNTNALATVNVGAGIATLEGAIIKATTTKLTNAASVLTLTNVNAVLTGAIDNTTGVDNVGVLNLNGALSQVTGNIGNTNALATISVGAGKATLGGAVIKATTTKLTDNASAVTFTNPVVVTGAIDNTGNANNGIVTFTGDSTVTGNIGNTNALATISVGAGKATLGGAIIKATTTKLTDNASAVTFTNPVVVTGAIDNTGNANNGIVTFTGDSTVTGNIGNTNALATISVGAGKATLGGAIIKATTTKLTDNASAVTFTNPVVVTGAIDNTGNANNGIVTFTGDSTVTGNIGNTNALATISVGAGKATLGGAIIKATTTKLTDNASAVTFTNPVVVTGAIDNTGNANNGIVTFTGDSTVTGNIGNTNALATISVGAGKATLGGAIIKATTTKLTDNASAVTFTNPVVVTGAIDNTGNANNGIVTFTGNSTVTGNIGNTNALATVNVGAGIATLEGAVIKATTTKLTNAASVLTLTNVNAVLTGAIDNTTGVDNVGVLNLNGALSQVTGNIGNTNALATISVGAGKATLGGAVIKATTTKLTDNASAVTFTNPVVVTGAIDNTGNANNGIATFTGDSTVTGNIGNTNALATVNVGAGLLRVQGGVVKSNTINLTDNASAVTFTNPVVVTGAIDNTGNANNGIVTFTGDSTVTGNIGNTNALATISVGAGKATLGGAIIKATTTKLTDNASAVTFTNPVVVTGAIDNTGNANNGIVTFTGDSTVTGNIGNTNALATVNVGAGVTLQAGGSLDANNIDFGARSTLEFNGPLDGGGNAIPYYFKGAIANGNNAILNVNTKLLTAYHLTIGTVAEINIGAGNLFAIDASAGDVTILNAQDIHFRALDSALVLSNLTGVGVNNILLAADLVAPGVDEGTVVFDGGVNGLNIGSNVAGAARNIGDVGGNKFNTLLIYNAVTITDDVNLEGIQNVLINNNADFTSSTAFNAGTIQINDATYTIDANNGNLNIPAGNIKFAHADAQLILQNSSGNDRTITLGANIDPDNDDEGIVILNSVTAGKKLTIAGGKTFGGAHKLQDIVFKGEGDFGTAGTTFNTTNIVLDITGQLELGATTANVVLFKDAVQLTQTGNIGGFLDFNAKNGTVTLNNNVNVAGTVKNTGGTNNGTLIVLGASNLNRVNGIAMLKVGAGNVTIAKGGNVKIGEIQGTGTNTLTLPAHFKLTGSINKTGGQALKLNFMNGGSVSGVVGTAANSVGDITTAGATSFASSVNAKGTATLGGTTSFAHTFTNTGAVTLAKGSITSFAKNVTATSFVANSATINFGNSLAFNSNITGSGTTLTLGANQVTYTGTGSFTDTLTLNTTFDGAAKSGGNILIKSGSTLDLSGVSNLALVVTATNFDMNNISPDTKYTVISAETAGGLKPTPKENVKITINNDNRFVDFTFDASTLTLFAEDIAAGVIDEDFAPGGPLANIPNAANIKKSLELMEDAPNGSDARQAFNNFGLMTPLQEADATTHLMQDVVKPSDTIAAVNNQVVASNISSNITALNARMDKVQAGNKGPVSSGDEDMDAKFGAWISPFVGNATQKMCNSISGYKSDTTGGTIGFDGFVSDDLVLGLAYTRADTDIKLKNNKTGDKNKVESNIYSLYGLYSVPYENLFVEAIASYSDNKIRSKSRRVIATTLETVGYQTANGKYKSESYTGQLMAGYTYMMSENINLTPLAGLRYSTIKDKSYKETGTTYQNLTVKGKNYNTFDGLLGAKVSSNINVNEIVLTPELYAMVDYAFKNKVSAIDARLQGMTAPLPTNSFKQSKTSFDVGVGVTAKHKMMEYGINYDTNIGSKYFAQQGSVKVRVNF
What is the function of this protein?
Elicits protective immunity.
What are the official names of this protein?
Outer membrane protein A, 190 kDa antigen, Cell surface antigen, rOmp A, rOmpA.
What is the protein family that this protein belongs to?
Belongs to the rickettsiae OmpA/OmpB family.
What are the subcellular locations of this protein?
[Outer membrane protein A]: Periplasm. SUBCELLULAR LOCATION: [120 kDa surface-exposed protein]: Secreted. Cell surface. Note=Surface exposed. This bacterium is covered by a S-layer with hexagonal symmetry. SUBCELLULAR LOCATION: [32 kDa beta peptide]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: URED_PARMW
Sequence: MQSLEPWHGRCRLQFQTNNGSTKHQGGCTAPFKLLRADVGDHGRCELPLLHTAGGLVGGDELSIELDLGPDSRSLITSVAAQKVYGSVGRSRLHPDGAWTQQSVTCRLEDTSDLEWLPQELVLYADALFQQTLTVSLPDNASFLSAEIVRLGRTAAGEQLNRGRWRSCLEIQRDGAHQPRWELVDRLELGDTSLNDPHGLGGAPVFGSLVWAAPMPLTGEQITLLLAGARHDRDGLEGTMRCSSLDQGLIARYAGHSSRDARFWFSRIWARTRALRGLSTPRIPRVWPLQEQPLTGQPFTANASPTAATTH
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP214_LYCMC
Sequence: MIRYVLVIITCFLVAAKSHVTIGPVPNNLGFPDRSILLALVAPTCEPELEGLVDECVNNVTIRNVCYDCFREGLTKVYSYCCHKYNHMYEWCLEYFSGEMK
What are the official names of this protein?
Venom protein 214.
What are the subcellular locations of this protein?
Secreted.
Protein: DAAF3_CHLRE
Sequence: MDEHNVHHFWGISPAVDLGTLLPTGDGAADLPVDQPVRFLQVAPYDARHTLTTLSRACRHPALMRQLPPGQPACRLYVWEDSPEGLARHVLLAAVLLDGGVPAAQRGQLLLELHGNAVLRRRAAEYLDEKARQLESLFVGLAAGQPPPAGPEAEARGLAALAALLDLSLLKFQEKDLIVEALQRWRLPNPTSSTSTSAASASAAAAPYDMVAAWDGRCRKVYGERYDFRRNMVDWDYHMRLQPAGTPGCDPASGSIIHFHHFRHWRLHGVAHELRDSAYNSANRCRGEGGVGEFKDRTGRDVGRSVSAWGFWADVLNSPYHAFGTACEQPEFYRITNKQFVRTAVDVAEHNIAALLHELRTGRRLELGEGQEAHRAQAARGPTTLEDLTAAAEEAAAAASGAGAEAGAGAGPGGEAAAGASSSSGKEEAAAAAAAGKEQGQGEGQGEDWTAGSGSGAPGAGTGQAVAEGREGPGGPQDSDPAAAASTAAPAAAAAAASSSSTSVPTYSSGGRAQVAKAMAAAAAAAGAGAGAGAEASSSGAASAASAAPTAGASSGAADGKAAEAAAAPLDEAAREQMAAEEAAVRAAEAALDAAARQRAGRFRLVLVTGDLAKTLTGRAKYAGAFSGLSLGHRHTHMLEPQYKLAAAAAPGARLVAENARHVLQLSQEQAALFAAKMDELAAAGGWRPLPAAQRPPGITEAAAVYVRAA
What is the function of this protein?
Required for the assembly of axonemal inner and outer dynein arms.  Involved in preassembly of dyneins into complexes before their transport into cilia.
What are the official names of this protein?
Dynein axonemal assembly factor 3 homolog, Dynein assembly blocked protein 1, Paralyzed flagella protein 22.
What is the protein family that this protein belongs to?
Belongs to the DNAAF3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_IDILO
Sequence: MALPKIYVALDCQTQEAADNLVSQLPAGKVGLKVGKELFTAIGPDWVKKQVEQGFSVFLDLKFHDIPNTVAKAVTSAAKIGVDIVNVHASGGTEMMSAARDALKQFDKPPLLIAVTVLTSMSDSDLNEIGIQATAEQQVLKLAKLAQQAGLNGVVCSAQEARMLKHDLGTSFKLVTPGIRPANSATGDQKRVMTPEAAIEAGVDYMVIGRPITQAADPTASVAEILTSIGE
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RS14_PHOPR
Sequence: MAKESMKAREAKRAKLVAKFAEKRAALKVIISDVNASEEDRWNAVLKLQSLPRDSSSSRQRNRCNQTGRPHGYLRKFGLSRIKVRETCMKGEIPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: CLU_BOTFB
Sequence: MAVNNEVNNAASETPTDVSSSSQKLATEETALTNGADHEEEDGGEAGGEVFQLTVVLPREPHKIQIIVSSQEAIHDVRQSIIELPGTFQYSCFHLEHKGERINDFVQISEVPGLTADSEIHLVEDPYTEKEARIHIIRVRELIGAAGDRTDTLNGIISGASLLDSVTSKESSQNGTSTAPSHPMVGFDFQGSGNLSTLLPRAQEPGPKTVKSISVSPWNPPPYHLRQKGHLLYLQVTTNEGEQFQITSHVSGFYVNKSSTGKFDPSPKSAPKAHSAHSLLALLSDLSPSFEESFKGLQEYNNAKEPLATFQITNATPSNPWIVPSATAPLVAHQADITRTQENYLIAGIENSETLRDWNEEFQSTRELPKDTVQDRVFRERLTSKLFADYNDAAARGAILVARGEIAPLNPTEGKDAQIFVYNNVFFSFGADGVGTFASEGGDEAARAAVGKDVMGVRMVNQLDIDGLFTPGTVVVDYLGKRIVGQSIVPGIFKQRDPGENQIDYGAVDGKDIVASDEKFVSVFEKLSKALKVKKHAVWDKDAKRHDLEGSIETKGLLGTDGRKYVLDLYRVTPLDITWMEEVGTALDSPKEADAASESAYPHRMTVIRPELVEAYWKVKMREWVNGELERKRQAQKAVEPAAEGKEIEAATEASEPAKSEEPPENGELAKKSESDEAAEPSKPDQERIDIGDFKFALNPDAFSGQQPQTDEEKTEFAEDEQQVRLVCEFLRKTVLPELVKDLKEGDVGFPMDGQSLSRLLHKRGINLRYLGQVATLADGKRLESLRILAVQEMVSRAFKHVAGNYLRYLPIPLTSSCIAHLLNCLLGTDLNAAPKPDVDEAIAALYPEADLKFKEVTPESLKQEIEGQVLRRFRYTLDSTWTAGIKHLQLLREVSLKLGIQLEMKPYHFTKQSQTESAAAPPATNGEATKEAAPTGKSTNGKKKKKNAREASPAAVVSANAASPVTFNPDDILNTVPVIKEASPRSSLAEEALEAGRISLLQDQKKLGQELLLESLSLHEQIYGILHPEVARVYNSLSMLYYQLDEKEAAMELARKAVIVSERTLGVDNAETLLNYLNLGLIAHASGETKLALTYIKHALDLWKVVYGPNHPDSITTINNAAVMLQHLKEYHDSRTWFEASLKICEEVYGKHSINAATLLFQLAQALALDQDSKSAVNRMRESYNIFLTELGAEDKNTKEAEKWLEQLTQNAVSIAKHAKDVQARRNRGIRVSPRVTLGQTQVQPQIGQTVEAAAGRDTPRGLDSRSIDELLKFIEGSDQSNQNKKRPGRSNPKRRGGAAATAGK
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Clustered mitochondria protein homolog, Protein TIF31 homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIM5_SAIBB
Sequence: MASGILGSIKEEVTCPICLELLTEPLSLDCGHSFCQACITANHKESMLHQGERSCPLCRLPYQSENLRPNRHLASIVERLREVMLRPEERQNVDHCARHGEKLLLFCEQDGNIICWLCERSQEHRGHNTFLVEEVAQKYREKLQVALETMRQKQQDAEKLEADVRQEQASWKIQIQNDKTNIMAEFKQLRDILDCEESNELQNLEKEEKNILKRLVQSENDMVLQTQSVRVLISDLERRLQGSVVELLQDVDGVIKRIEKVTLQKPKTFLNEKRRVFRAPDLKRMLQVLKELTEVQRYWAHVTLVPSHPSYTIISEDGRQVRYQKPIRHLLVKVQYFYGVLGSPSITSGKHYWEVDVSNKRAWTLGVCVSLKCTANQSVSGTENYQPKNGYWVIGLRNAGNYRAFQSSFEFRDFLAGSRLTLSPPLIVPLFMTICPNRVGVFLDYEARTISFFNVTSNGFLIYKFSDCHFSYPVFPYFNPMTCELPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2.
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha, Tripartite motif-containing antiviral factor.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: RL30_METC4
Sequence: MATKTVRIEQIGSPIRREASQRATLVGLKLNKLHRVSELEDTPSVRGMIRKVAHLVRVLDDAAA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: EFG_BRUA1
Sequence: MAREYKIEDYRNFGIMAHIDAGKTTMTERILFYTGKNHKIGETHDGASTMDWMEQEQERGITITSAATTTFWQGRDGKKRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQAEKYHVPRMVFVNKMDKIGADFYRSVEMVGSRLGAVALPVQLPIGAENDFVGVVDLIEMKALTWDGTIGAPATVGEIPADMADKAEEYREKLIELAVEIDEAAMEAYLEGTMPTNDELRALIRKGTIEVKFHPILCGTAFKNRGVQPLLDAVVEFLPAPTDVPAIKGIDVKTETETTRESSDEAPLSMLAFKIMNDPFVGSLTFARIYSGKLTKGVSLENTVKGKRERIGRMLQMHSNSREDIDEAFAGDIVALAGLKETTTGDTLCDPLKPVILERMEFPDPVIEIAIEPKTKADQEKMGIALNRLAAEDPSFRVKSDEESGQTIIAGMGELHLDILVDRMKREFKVEANVGAPQVAYRESITRAAEIDYTHKKQSGGSGQFARVKIIFEPHDGDDFIFESKIVGGSVPKEYIPGVQKGIESVMGAGPLAGFPMLGVKATLIDGAYHDVDSSVLAFEIASRAAFREGAQKAGAQLLEPIMKVEVVTPEDYVGDVIGDLNSRRGQISGTEARGIAAVVNAMVPLANMFGYVNSLRSMSQGRAQYTMQFDHYEPVPTAVAQEIQKKFA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_VARPS
Sequence: MAKIQARTQNEGPEDGLREKMIAINRVTKVVKGGRILGFAALTVVGDGDGRVGMGKGKSKEVPAAVQKAMEEARRNLAKISIKNGTLHHRVTGHWGAASVVMIPAPKGTGIIAGGPMRAVFEVMGITDIVAKSHGSSNPYNMVRATLDGLKNSTTASEVAAKRGLTVEEIFA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PSAJ_PORPU
Sequence: MNNNFTKYLSTAPVIGVLWMTFTAGFIIELNRFFPDVLYFYL
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RNPA_SYNE7
Sequence: MALPRCHRLRQRDRFPALYRGGRKLSTPSLLLRWLPQAEIESVNESRFAIVISLKVHKRAVRRNRLRRRLQAALLRLRDRLRPGFDGLLTVKPGLDLDTSTSQFLQELEDLLTRAEIIHGRQ
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: TOP1_THEMA
Sequence: MSKKVKKYIVVESPAKAKTIKSILGNEYEVFASMGHIIDLPKSKFGVDLEKDFEPEFAVIKGKEKVVEKLKDLAKKGELLIASDMDREGEAIAWHIARVTNTLGRKNRIVFSEITPRVIREAVKNPREIDMKKVRAQLARRILDRIVGYSLSPVLWRNFKSNLSAGRVQSATLKLVCDREREILRFVPKKYHRITVNFDGLTAEIDVKEKKFFDAETLKEIQSIDELVVEEKKVSVKKFAPPEPFKTSTLQQEAYSKLGFSVSKTMMIAQQLYEGVETKDGHIAFITYMRTDSTRVSDYAKEEARNLITEVFGEEYVGSKRERRKSNAKIQDAHEAIRPTNVFMTPEEAGKYLNSDQKKLYELIWKRFLASQMKPSQYEETRFVLRTKDGKYRFKGTVLKKIFDGYEKVWKTERNTGEFPFEEGESVKPVVVKIEEQETKPKPRYTEGSLVKEMERLGIGRPSTYASTIKLLLNRGYIKKIRGYLYPTIVGSVVMDYLEKKYSDVVSVSFTAEMEKDLDEVEQGKKTDKIVLREFYESFSSVFDRNDRIVVDFPTNQKCSCGKEMRLSFGKYGFYLKCECGKTRSVKNDEIAVIDDGKIFLGRKDSESGSPDGRSVEGKGNLSEKRRKGKKGS
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: YIDD_RICPU
Sequence: MTRILLLLLRFYQYFISPLLGNNCRFHLTCSEYAKEAISMHGSIKGLWFTFKRIIKCQPFCDGGYDTVPISIKNSKPLNKKI
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RUVC_PROMH
Sequence: MAIILGIDPGSRVTGYGVIRQQGRQLIYLGSGCIRTQVPDLPSRLKRIYAGVSEIITQFSPDVFSVEQVFMAKNADSALKLGQARGVAILAAVNNDLPVFEYAARQVKQSVVGTGGADKSQVQHMVRSILKLSAAPQADAADALAIAITHCHFNQNLLRVGDPRLVLTRGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MALQ_MYCBO
Sequence: MTELAPSLVELARRFGIATEYTDWTGRQVLVSEATLVAALAALGVPAQTEQQRNDALAAQLRSYWARPLPATIVMRAGEQTQFRVHVTDGAPADVWLQLEDGTTRAEVVQVDNFTPPFDLDGRWIGEASFVLPADLPLGYHRVNLRSGDSQASAAVVVTPDWLGLPDKLAGRRAWGLAVQLYSVRSRQSWGIGDLTDLANLALWSASAHGAGYVLVNPLHAATLPGPAGRSKPIEPSPYLPTSRRFVNPLYLRVEAIPELVDLPKRGRVQRLRTNVQQHADQLDTIDRDSAWAAKRAALKLVHRVPRSAGRELAYAAFRTREGRALDDFATWCALAETYGDDWHRWPKSLRHPDASGVADFVDKHADAVDFHRWLQWQLDEQLASAQSQALRAGMSLGIMADLAVGVHPNGADAWALQDVLAQGVTAGAPPDEFNQLGQDWSQPPWRPDRLAEQEYRPFRALIQAALRHAGAVRIDHIIGLFRLWWIPDGAPPTQGTYVRYDHDAMIGIVALEAHRAGAVVVGEDLGTVEPWVRDYLLLRGLLGTSILWFEQDRDCGPAGTPLPAERWREYCLSSVTTHDLPPTAGYLAGDQVRLRESLGLLTNPVEAELESARADRAAWMAELRRVGLLADGAEPDSEEAVLALYRYLGRTPSRLLAVALTDAVGDRRTQNQPGTTDEYPNWRVPLTGPDGQPMLLEDIFTDRRAATLAEAVRAATTSPMSCW
What are the official names of this protein?
4-alpha-glucanotransferase, Amylomaltase, Disproportionating enzyme, D-enzyme.
What is the protein family that this protein belongs to?
Belongs to the disproportionating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTA3_MOUSE
Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEESETPVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEACLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYKPNPNQISSSNGKAGTVNGAVGTQFQPQSALLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSDEEKSPSPTAEDPRARSHMSRQALQGMPVRNTGSPKSAVKTRQAFFLRTTYFTKIARQVCKSTLRLRQAARRPFVAINYAAIRAEYADRHAELSGSPLKSRSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPATKRMLAAPNHTSLSILGKRNYSHHNGLDGPERWLSR
What is the function of this protein?
Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin.  Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.  Contributes to transcriptional repression by BCL6.
What are the official names of this protein?
Metastasis-associated protein MTA3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: IMPC2_SALTM
Sequence: MLRINVCFDASKKVPAKIQQALRAEIEKEILSNYERGVVSVGKGSSAEVSISGVDDDEKKVIMQKLEDIWQSDSWLP
What are the official names of this protein?
Protein ImpC.
What is the protein family that this protein belongs to?
Belongs to the DinI family.
Protein: NUCS_AERPE
Sequence: MSQEASVDGRFGVASSPTIEEAAGLLEKLLDGSSMVVVAGVCSSEYEGRGASVSTEGDKLLIVKPGGAVILHGPRGFRPLNWQPSTSHTEVATADGLLTLKFYRRTPREVLKIACGSIWYIAWVRFPEEGAFWMYMTEDDLRKAVALHPRELLGEDIRFFAEEKRTPSGKADLYGVDERGNIVIVEVKRVRADESAVRQLEGYVRDYPTQAKVRGILVAPDISDAARRLLESRGLEFRRVDLKKAYSLLKPGRGRSVLDFL
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_CAMJD
Sequence: MIKLTQEEQKYLLDSIRIIPDFPKKGIIFRDITTLLNNKEALNFLLKHLKERYKDYNLDFIAGTESRGFIFASMICAKLNLPFVPIRKPGKLPFETFSCEYDLEYGSDKVELHKDAFKNIQNARVLLVDDLIATGGTAIASYELIQKAGAKCVEACFLMNLKDLNGANKLEKLTSVYSVLEI
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAC10_ORYSJ
Sequence: MESPDSSSGSAPPRVLRRQQQQPGSAPELPPGFRFHPTDEELVVHYLKKKAASVPLPVTIIAEVDLYKFDPWDLPEKANFGEQEWYFFSPRDRKYPNGARPNRAATSGYWKATGTDKPIMSSGSTREKVGVKKALVFYRGKPPKGVKTNWIMHEYRLTDTSSSAAAVATTRRPPPPITGGSKGAVSLRLDDWVLCRIYKKTNKAGAGQRSMECEDSVEDAVAAYAPSSQQHATAAAGMAGSDGAGGVAAAHGGDYSSLLHHDSHEDTFLVNGLLTAEDAAGLSTGASSLSQLAAAARAAATPCDATKQLLAPSPTPFNWFEAFLPRAKEFPSGLSRSSRDIGDMSLSSTVDRSLSEAGAVAIDTGDAANGANTMPAFINPLGVQGATYQQHQAIMGASLPSESAAAAAACNFQHPFQLSRVNWDS
What is the function of this protein?
Transcription factor of the NAC family associated with male fertility.  Involved in anther development, but not in senescence.  Reduced expression of NAC5 via RNAi leads to male-sterility.
What are the official names of this protein?
NAC domain-containing protein 10, ONAC010, NAC transcription factor ONAC010.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPA_PSEAO
Sequence: MLPNQNRLRRREDFAKVYAKGDRYRGTYLSLKILFDSNTTYTRIGIVVSKKVSKLAVTRNRFKRQLRAIFRQLLSQLKDGLQIVVTVTTVASKPNYQELGDDLKNILAKAKVLHGN
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RS16_SULDN
Sequence: MATVIRLTRMGRKKQPFYRIAVTDSRKRRDGGWIELIGHHNPMVAEKTTVVDNERLDYWLSVGAKMSDRVKKITGR
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RPO12_SULAC
Sequence: MAKYRCGKCWKELDDDQLKTLPGVRCPYCGYRIIYMVRKPTVKIVKAI
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo12, DNA-directed RNA polymerase subunit P.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOLW_RHIFR
Sequence: MPTTPIPFTPLHMFRRLLCVGLFLFAGIHTTLGATLPLPSTSYKYTVLDQDLSAALQEFGNNLKISVNISAEVKGRIRGRIPELSPREFLDRLTDLYDLQWYYDGVVLYVSAAKEAQTRMLVLSSVHFSAFKLALDKLDISDERYPVRPAPGNGLVLVSGPPRFIALIEQTLNGLLAVAQAQPRATDTPARESVMVLFRGSSTTVVRGGRPEVFYTSEMLPENDDGGKAELSKK
What is the function of this protein?
Regulates cultivar-specific nodulation of soybean.
What are the official names of this protein?
Nodulation protein NolW.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y3175_ALTMD
Sequence: MGRAFEVRKAAMAKTAGAKTKVYSKYGKEIYVCAKNGGADPDTNLSLRRLMEKAKKDQVPSHVIEKAIDKAAGGAGEDFQPMRYEGFGPGNCMVIVDCLSDNANRTITEVRNCFTKTNAKLGAQGAVSHMFDHQAVFQFEGDDEDAILEVLMEADVDVTDVEVEDGKVTVYAPHTEFYQVRTALTEAYPDLSFIADEISWMPQTETEISEEDMPMFEKFMDMLNDCDDVQDVYHNAVTPS
What are the official names of this protein?
Probable transcriptional regulatory protein MADE_1004275.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.