PharMolix/UniProtQA huggingface dataset:
Protein: YIDD_GLOVI
Sequence: MELVRRAATGAIRFYQRFVSPLTPPTCRYVPTCSEYTRQAIERFGVAAGIWLGTKRLCRCHPLHPGGYDPVPERRSVR
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL21_DESHY
Sequence: MYAVIETGGKQFRVEEGKVLFVEKLDANVGDTVTIDKVLLVEKDGAVKVGTPVVDGAKALLKVVEHGKGEKIIVFKMKSKKNYRRKQGHRQPYTKVVVEAIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL27_PARXL
Sequence: MAHKKAGGSSRNGRDSESKRLGVKVYGGQAINAGGIIVRQRGTRMHPGENVGMGKDHTLFALTDGHVNFSTKGAAKKHMVNVVPAAV
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: YDBP_BACSU
Sequence: MKKITTNEQFNELIQSDKEIIVKFYADWCPDCTRMNMFIGDILEEYNQNDWYELNKDELPDLAEKYQVMGIPSLLIFKNGEKTAHLHSANAKTPEEVTEFLSEHIS
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin-like protein YdbP.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: RS6_DEIRA
Sequence: MNQYDLNLILNPNISAEQVQTEKDYIENAVRNAGAEISNLDDLGNRRLAYQVGKDREGYYLMYTIKASGNPETAIASSLRLRDNVRRVLVVKDRPEWKTKKA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: ASZ1_ATEAB
Sequence: MAAGAMRGLAVAGGGESSDSDDDGWEIGYLDRAAQKLRGPLPTEEKNETFKKALTTGDISLVQELLDSGISVDTSFRYGWTPLMYAANVANVEMVQVLLDRGANASFSKDKQTILISACSARGTEEQILKCVDLLLSRNADPNMACRRLMTPVMYAARNGHPQVVALLVAHGADVNAQDENGYTALTWAARQGHKHVVLKLLELGANKMIQTKDGKTPSEIAKRNKHVEIFNFLSLTLNPLEGKLQQLTKEETICKLLTTESDKEKDHIFSSYTAFGDLEIFLHGLGLEHMTDLLKERDITLRHLLTMRKDEFAKNGITSRDQQKILAALKELEVEEIKFGELPEVAKLEISGDEFLNFLLKLSKQCGHLITAVQNIITELPVNSHKIVLEWASPRNFTSVCEELVSNVEDLSEEVCKLKDLIQKLQNERENDPTQIPLIEEVSTWNSRILKRTAITVCGFGFVLFICKLTLQRK
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: RIMP_SYNY3
Sequence: MTHPVIPDILALAQPIAEDLGLEVTDAVFQTNKRPPVLRIDIRNLQQDTSLNDCEAFSRSFEAQLEESSLIASAYVLEVSSPGISPYLATERDFIAFKGFEVVVTSDNPHQGQSQWQGSLQGRDGEAVYLSIRGRTVAIPLTVGLTVRLPH
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UDPE_GVLO
Sequence: MFISILLLALAVERILCANILCVFPTPAYSHQSVFSAYIDKLSWAGHNVTVITPMPRAVDHVHQVVSSLSVHYFNNLIKNSTMIKKRGVVADETTVTKENYMGLINLVAHEIKSPNVTRLLRNKGNKFDLIVCEAYVSYILVFGAIYDAPVIQFSSGYAIPENFETVGGEVARNHIKHPNIWRSDFSKSNFEQLMTENYLKNEWALLEKEQENMLKRDFGYHHDMCQLKSRVLMLFINVPAVFDNNRDVSNNIQYLGGIHLKKPRTVRDSRLLSFMEKHHIIVYASFGSGIDVLNMDANLIAEFVRVFNSIPYAVLWKVDSSIHLKHNISSNVHTQSWFPQRDVLNHPHIKVFITQGGVQSTDEAVNSGVPMIGIPIMGDQFYNVRRYTELGIGEKVNILRLEEEGLDRKIKNLVHNKSYELNIKRLNLFISDTPVKPLRKALWFTNYVLRNKDAIDKFK
What is the function of this protein?
Catalyzes the transfer of glucose from UDP-glucose to ecdysteroids which are insect molting hormones.  Expression of egt interferes with normal insect development and block molting (By similarity).
What are the official names of this protein?
Ecdysteroid UDP-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: LACC_LACLL
Sequence: MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTRVLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEILEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAVVLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEWIVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKHAMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: WZYE_YERPA
Sequence: MTLGQFGGLFCIYLIAVIFILTLTYQEFRRVKFNFNVLFSMLYLLTFYFGFPLTCMLVFQFGVAVVPVEYLLYAMLSATAFYGIYYVTYKTRLRQPRSQPRTPIFTMNRVETNLTWVLLALVAVGTVGIFFMQNGFLLFKLDSYSKIFSSDVSGVALKRFFYFFIPAMLVVYFLKQDRRAWFFFLASTVAFGILTYVIVGGTRANIIIAFSLFLFIGIVRGWITLWMLAAAGVFGIVGMFWLALKRYGLDVNGAEAFYTFLYLTRDTFSPWENLGLLLQNYDKIDFQGLAPIVRDFYVFIPSALWPERPDLVLNTANYFTWDVLDNHSGLAISPTLIGSLVVMGGVLFIPLGAIVVGLIIKWFDWLYEQGKAESNRYKAAILQSFCFGAVFNIIVLAREGLDSFVSRVVFFCVIFGACLVLAKLLYWLFDTAGLIKRQGIKSNRLSTPNAGNQL
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HARS1_MOUSE
Sequence: MADRAALEELVRLQGAHVRGLKEQKASAEQIEEEVTKLLKLKAQLGQDEGKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMIPDAECLKIMCEILSSLQIGNFLVKVNDRRILDGMFAVCGVPDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQAVEGLGDLKLLFEYLILFGIDDKISFDLSLARGLDYYTGVIYEAVLLQMPTQAGEEPLGVGSIAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEASEEKVRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVASREEVDVRREDLVEEIRRRTNQPLSTC
What is the function of this protein?
Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP).  Plays a role in axon guidance.
What are the official names of this protein?
Histidine--tRNA ligase, cytoplasmic, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_BRUA4
Sequence: MRHGNGQRKLNRTASHRKAMFANMAASLIEHEQIVTTLPKAKEIRPIVEKLVTLGKRGDLHARRQAISAIRDVKLVAKLFDTLAARYATRNGGYIRIMKAGFRAGDNAPLAVVEFVERDVDAKGKADRARVEAEQAAEADAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SYH_CLOD6
Sequence: MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIFEHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPTKLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLVVSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIKDIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGAQSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVTIGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKNDTATLKNMKTSEQTTVKLSTLVEELKQKL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESXV_MYCTU
Sequence: MTINYQFGDVDAHGAMIRAQAGSLEAEHQAIISDVLTASDFWGGAGSAACQGFITQLGRNFQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA
What is the function of this protein?
Probable virulence factor.  In mice, elicits increased levels of IFN-gamma, IL-12 and IgG(2a), indicating a dominant Th1 host immune response.
What are the official names of this protein?
ESAT-6-like protein EsxV, Antigen Mtb9.9B.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. ESAT-6 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS) (Probable). May bind to lipid membranes after dissociation of the complex (Probable).
Protein: PETD_SOLBU
Sequence: MGITKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y2047_MYCTU
Sequence: MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIRDATAVESAMTGADVVAHCAWVRGRNDHINIDGTANVLKAMAETGTGRIVFTSSGHQPRVEQMLADCGLEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLLVRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAELELLHSAPLMDVTLLRDRWGFQPAWNAEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAGPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATIVSNSGFFGPSMASLPIFGAQRPPSESSRARRWLRTLRNIGVFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAAARRDPVVIRLLAEPGERLDKLAVEAPEFHSAVLAELTLIGHRGPAEVEMAATSYADNPELLVRMVAKTLRAVPAPQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEIDALPADVSGLVARRRAEQRRLAGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVRPETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR
What are the official names of this protein?
Uncharacterized protein Rv2047c.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: RNFC_YERP3
Sequence: MFKLFTARQHDKIWDFDGGIHPPEMKLQSSTVPMRIAPLPDQLIIPLQQHLGPEGELRVRAGEQVLKGQPLTVGRGRTVPVHAPTSGMITAIAPHTTAHPSGLAELCVHITPDGEDRWREQQPWADYRQRDKMALLDRIHQAGIAGLGGAGFPTASKLQGGLNGIITLIINAAECEPYITADDRLMQEHADEVITGIHILRHLLQPQQVLIGIEDNKPEAIAALQRALRGQDDIHLRVVPTKYPSGGAKQLTKILTGKEVPFGKHSSSIGVLMQNVGTVVAIKRAVIDDEPLIERVVTLTGDALSSPGNFWARIGTPVLYLLKLAGFKPQNPPMVIMGGPLMGFTLPSLDVPIVKISNCILAPAETEMGLSEPEQSCIRCGLCVDACPAGLLPQQLYWFSRGEEHEKARNHNLFDCIECGACAYVCPSNIPLVQYYRQEKAEIRALDQESARAAEAKARFEAKQARLAREKLARELRHKQAAVKLTDADQQTVDAAVSRLTRQSDGSESVINIPAGQMPDNSAVIAAREARKAQARARQAEKQQARSTEETTDVVDPRQAAVAAAIARVKAKKAAQVQHVTTDVAEAGSEAIAEDPRKAAVAAAIARVKAKKAAQAQHVTTDVAEAGSEAMAEDPRKAAVAAAIARVKAKKAAQAQHVTTDVAEAGSEAIAEDPRKAAVAAAIARVKAKKAAQAINPD
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rnf electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GPR19_RAT
Sequence: MGFDHRMETDQPPVVTATLLVPLQNGSCVEAAEALLPHGLMELHEEHSWMSNRTDLQYELNPGEVATASIFFGALWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVVLQFTTGRWTLGSAMCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKRMIAASWILDAAFVTPVFFFYGSNWDSHCNYFLPPSWEGTAYTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTLRRTMNIVPRTKVKTVKMFLLLNLVFLFSWLPFHVAQLWHPHEQDYRKSSLVFTAVTWVSFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTITTSSRMAKRNYVGISEIPPVSRTITKDSIYDSFDREAREKKLAWPINSNPPNTFV
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 19.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BAMS_GLYGL
Sequence: MWRLKIAEGGKDPYIYSTNNFVGRQTWEYDPDGGTPEERAQVDAARLHFYNNRFQVKPCGDLLWRFQILRENNFKQTIASVKIGDGEEITYEKATTAVRRAAHHLSALQTSDGHWPAQIAGPLFFLPPLVFCMYITGHLDSVFPEEYRKEILRYIYYHQNEDGGWGLHIEGHSTMFCTALNYICMRILGEGPDGGQDNACARARKWIHDHGGVTHIPSWGKTWLSILGVFDWCGSNPMPPEFWILPSFLPMHPAKMWCYCRLVYMPMSYLYGKRFVGPITPLILQLREELFTEPYEKVNWKKARHQCAKEDLYYPHPLLQDLIWDSLYLFTEPLLTRWPFNKLVREKALQVTMKHIHYEDETSRYITIGCVEKVLCMLACWVEDPNGDAFKKHLARVPDYLWVSEDGMTMQSFGSQEWDAGFAVQALLATNLVEEIAPTLAKGHDFIKKSQVRDNPSGDFKSMYRHISKGSWTFSDQDHGWQVSDCTAEGLKCCLLLSMLPPEIVGEKMEPERLYDSVNVLLSLQSKKGGLSAWEPAGAQEWLELLNPTEFFADIVVEHEYVECTGSAIQALVLFKKLYPGHRKKEIENFIANAVRFLEDTQTADGSWYGNWGVCFTYGSWFALGGLAAAGKTFANCAAIRKAVKFLLTTQREDGGWGESYLSSPKKIYVPLEGSRSNVVHTAWALMGLIHAGQAERDPAPLHRAAKLIINSQLEEGDWPQQEITGVFMKNCMLHYPMYRDIYPMWALAEYRRRVPLPSTPVCLT
What is the function of this protein?
Oxidosqualene cyclase converting oxidosqualene into beta-amyrin, generating five rings and eight asymmetric centers in a single transformation.  Required for the production of soyasaponins and glycyrrhizin.
What are the official names of this protein?
Beta-amyrin synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: GCSH_BIFLO
Sequence: MTMSDDNENEQPLNLDIPDHLEYSEEHAWVDRSVDPAIIGITEYAADQLGELVFVDLPEPGARVEAGDEIVELESSKAVQPLISPVAGTVKYVNRDVADDPSVVNGDPYGEGWLLKVELDDDEPELLSADEYAKVVR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: MNME_STAAM
Sequence: MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRSVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFYB_DICDI
Sequence: MSGNEDFIYDDNSSSSISNQTDGGGGGGSSNNNSGGNANNNNNEGDREQDRYLPIANIIRIMKKALPNNAKVAKDAKETVQDCVSEFISFITSEASDKCQQEKRKTINGEDIIAAMVSLGFENYVEPLKVYLLKYRETEKNSNNKRSPKKSESSSPPESPPLAHLDNSINSGYQPPPPPQQQQQQPPQVQQQQQQQQQQQQQQLQQQQQLQQHQQQQLQPQQQQQHLQQHLQQQQPQQQQQPPQQQQQQLTTTTTTTSTNNQQYQQQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVQPPYILQQHNIQQPNVFLNQQAQQQQQQQQQQQQPMMNIQSHQQQFPQQHQIQQHLQQQHQHLQQIHNMQPPHQQMQFNQQFQMSQQIQMPQQFSNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNNNPNNNINNNLNNSSNSLHNSGNSLHNSGNSGQIPPLYQQPYISTNPEYPSTS
What is the function of this protein?
Component of the NF-Y/HAP transcription factor complex.  The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity).
What are the official names of this protein?
Nuclear transcription factor Y subunit beta, CAAT box DNA-binding protein subunit B, Nuclear transcription factor Y subunit B, NF-YB.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOLD_YERPP
Sequence: MSAKIIDGKTIAQQVRNEVAAVVQQRLAAGKRAPGLAVVLVGENPASQIYVASKRKACEEVGFVSRSYDLPMATSEAELLALIDSLNEDTEIDGILIQLPLPNGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPKLRACTPRGIMTLLERYDIPTYGLNAVVVGASNIVGRPMSLELLLAGCTTTVTHRFTKNLRHHIENADLLVVAVGKPGFIPGEWIKPGAIVIDVGINRLESGKVVGDVAFDVAAERAGWITPVPGGVGPMTVATLIQNTLQACEEYHDISQN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SP17_RABIT
Sequence: MSIPFSNTHYRIPQGFGNLLEGLTREILREQPDNIPAFAAAYFENLLEKREKTNFDPAEWGAKVDDRFYNNHAFQEHESEKCEAEEKSQSVTEEETPVLTIDSEDDKDKEEMAALKIQAAFRGHLAREDVKKIRTNKAEEETEENN
What is the function of this protein?
Sperm surface zona pellucida binding protein.  Helps to bind spermatozoa to the zona pellucida with high affinity.  Might function in binding zona pellucida and carbohydrates.
What are the official names of this protein?
Sperm surface protein Sp17, Sperm autoantigenic protein 17.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: ITB5_PAPCY
Sequence: DLSLSMKDDLDTIRNLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGCFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSVEARSCPSRHTEHVFALQPVGCRDSLEVGVTYNCTCGCSVGLEPNSARCSGTGTYVCGLCECSPGYLGTRCECQDGENHSVYQNLCRDTEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECPLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTVD
What is the function of this protein?
Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin.  It recognizes the sequence R-G-D in its ligand.
What are the official names of this protein?
Integrin beta-5.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ISPG_SINMW
Sequence: MSSAFDFEPQPRRASVAVDVGGVIVGGGAPVVVQSMTNTDTADIDATVAQVAALHKAGSELVRITVDRDESAAAVPKIRERLLRLGLDVPLVGDFHYIGHKLLADHPACAEALAKYRINPGNVGFKDKKDKQFAEIVEMAIRYDKPVRIGVNWGSLDQELLTRLMDANKANGFPLTAQQVTRETIVQSALLSAELAEELGLPRNRIILSAKVSGVQDLIAVYAMLSARSDHALHLGLTEAGMGTKGIVASSASLGILMQQGIGDTIRISLTPEPGGDRTREVQVAQELLQVMGFRQFIPVVAACPGCGRTTSTVFQELAQKIQEDIRSSMPVWREKYPGVEALKVAVMGCIVNGPGESKHADIGISLPGTGEMPAAPVFIDGHKAMTLRGPKIAEDFQLLVADYIEKRFGHGQAAAE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GRPE_CAEEL
Sequence: MLRKGVSFVGQAVQQTLKTQKNLRIQRFSATASQSSEEVNYEIRKDGKRLRGADYEEIVLTSIAGEDKTQIPKGAFDVLLKEYDDLQAESLDFKDKYQRSLAETENVRRRGIKQTDDAKVFAIQSFCKDLLEVSDILDIAVKSVKPEDLESGGKALKDLFEGVSMTRTVMAKTFAKHGLVTVDPTNEKFDPNLHEAVFQIPSANAKQPVGHIEVCTKIGYSLKERPIRPAQVGVVSK
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
What are the official names of this protein?
GrpE protein homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SRK2F_ARATH
Sequence: MERYDILRDLGSGNFGVAKLVREKANGEFYAVKYIERGLKIDEHVQREIINHRDLKHPNIIRFKEVFVTPTHLAIVMEYAAGGELFERICNAGRFSEDEGRYYFKQLISGVSYCHAMQICHRDLKLENTLLDGSPSSHLKICDFGYSKSSVLHSQPKSTVGTPAYVAPEVLSRKEYNGKIADVWSCGVTLYVMLVGAYPFEDPEDPRNIRNTIQRILSVHYTIPDYVRISSECKHLLSRIFVADPDKRITVPEIEKHPWFLKGPLVVPPEEEKCDNGVEEEEEEEEKCRQSVEEIVKIIEEARKGVNGTDNNGGLGLIDGSIDLDDIDDADIYDDVDDDEERNGDFVCAL
What are the official names of this protein?
Serine/threonine-protein kinase SRK2F, OST1-kinase-like 5, SNF1-related kinase 2.7, SnRK2.7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: NSP4_ROTE2
Sequence: MDKLTDLNYTLNVITLLNSTLHTILEDPGMAYFPYIASVLTVLFTLHKASIPTMKIALRTSKCSYKVIKYCIVTIFNTLLKLAGYKEQITTKDEIEKQMDRVVKEMRRHLEMIDKLTTREIEQVELLKRIYDKLMARATDEIDMTKEINQKNVKTLEEWENGKNPYESKRMTAAM
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.