PharMolix/UniProtQA huggingface dataset:
Protein: RL3_SHISS
Sequence: MIGLVGKKAGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFAEVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: MNTH_STAAM
Sequence: MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTFIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSRTYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FAPD_HALH5
Sequence: MFKLSVIEELLAHVDKNKEELLALVQTLVAYPTPSPPARNTADAQQYIRTYCEKLGCNVDMWDVYPNDPNVVAVLKGTYSESYRSLILNGHIDVAAVDESEEWKTPPFEATVNQGVIRGRGVADMKGGLAACLFAMKTLHAFNIQLPGDLIFQSVVGEEVGEAGTKSCCERGYTADLAIVSDTSHCEIQGQGGVITGWITVKSPVTFHDGTRRNLIHAGGGEFGASAIEKMMKLIQGLQELERHWAVTKSSPGFPPGMNTINPAFIEGGRHPAFIADECKLWITIHYYPHESYEEIVREVEEHLLHVAKADPWMREHPPSFSWGGTSMIEDKGEIFPAFQIDEQSDAVQLLKKIHYHLTGEEVKTSMSQTVTDGGWLAEAGIPTLLFGPGKLEDAHSVNEELEIAELVQYTKTLLTFIYEWCHLRKA
What is the function of this protein?
Catalyzes the deformylation of the formylaminopyrimidine N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP) to give the corresponding aminopyrimidine.
What are the official names of this protein?
N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase, Formylaminopyrimidine deformylase, Amidohydrolase YlmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: HIS1_ARCFU
Sequence: MRPQIMPFYIEMGKGDGGITGEDILQNWMLKSNLKNVEILEELPLRPTKLVVAISEEIYPDVYTIEDFKEKVGDREVFIASEFPEIARKYAEKHGLNAIVFDPIGKTEAALLPPMPEADLIIEITEFGTTLKENMCRIIDLVMDKVHSVFIVNKESLKDEEKKQVMENLVTDLKEVIESRNLVSFYFNVPNEDDLRRIIDYLTENGFDPTISPLAKGGAAVHIIVDRSRVKFLKPIIRGMGAKRIATSPVITSGTNRAAQQKPFYLLSGIQREFPSASPFF
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OOSP1_BOVIN
Sequence: MKPSSGLRGLLVLFSLTWTCAGDWSAVKVRCSYFWFYAKIKPTLFHNLYMNPDEAFLGNDCPVTYVSPDAHYEFFYYSNKCGIITKTFQETLLLQTKIKYMSSNSGDTAEMPVSCVVTQQACMYHLSNETESGDDETSSEDMEVSYIMQSQNDLNTTFSLCAK
What is the function of this protein?
May be involved in cell differentiation.
What are the official names of this protein?
Oocyte-secreted protein 1.
What is the protein family that this protein belongs to?
Belongs to the PLAC1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPA_COREF
Sequence: MLPAQNKLTSSVQFRTTMRKGRRAGSSTVVVHLWDSAESLDGTGEKGEVASFGGPRFGLIVSKAVGNAVIRHRTSRRLRHVCARIAADSPELLTPTHHVVIRALAGSGQASSQDLERDIRHGLRKAGRVRTDK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: IF1C_CALFG
Sequence: MKEQKLIHEGLITESLPNGMFRVRLDNEDLILGYVSGRIRRSFIRILPGDRVKIEVSSYDSTRGRIIYRLRNKDSND
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GEP5_CANGA
Sequence: MSGRVLEVFRGLPLLPLSHEIVARCWDRMVRQRDVYYQFAVHVSHCHERLSTRNLLRLVTHVHHVLAPMNELPAHLRQYQSEYHALVASWPTVTERQILDAMELGKGMAVRIPHNKTLRQMFEQHEWLVQQRLLDDKRLKRRRLLRCEVQMATPTTNGSTNGNTNGSEISFRQCPLTIRELTPLGALESEAKFKNRVRSDVHSLWRLLAVQHPPLSRPHADELVRTLKRTLGTSRTDRSIARAYLQLLQRAYTYTYTYTDTEAEAQLQYSRVSQLVSH
What is the function of this protein?
Essential for respiratory growth and required for maintenance of mtDNA.  Required for cell survival in the absence of prohibitins (By similarity).
What are the official names of this protein?
Genetic interactor of prohibitin 5, mitochondrial, Required for respiratory growth protein 5.
What is the protein family that this protein belongs to?
Belongs to the GEP5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MHX_ARAHH
Sequence: MASILNQTQELQEASKVLGHVRCENFFIFPGENTLSDGLRGVLYFLGLAYCFIGLSAITARFFKSMENVVKHSRKVVAIDPITKAEIITYKKVWNFTIADISLLAFGTSFPQISLATIDAIRNIGERYAGGLGPGTLVGSAAFDLFPIHAVCVVVPKAGELKKISDLGVWLVELVWSFWAYIWLYIILEVWSPNVITLVEALLTVLQYGLLLVHAYAQDKRWPYLSLPMSRGDRPEEWVPEEIDTSKDDNDNDVHDVYSDAAQEAVESGSRNIVDIFSIHSANNDTGITYHTVADTPPDSATKKGKAKNSSVFDIWKHQFVDAITLETSESKKVDSIYLRIANSFWQLLLAPWKLLFAFVPPCNIAHGWIAFIFSLLFISGVAFVVTRFTDLISCVTGINPYVIAFTALASGTSWPDLVASKIAAERQLTADSAIANITCSNSVNIYVGIGVPWLINTVYNYFAYREPLYIENAKGLSFSLLIFFATSVGCIVVLVLRRLIIGAELGGPRLWAWLTSAYFMMLWVVFVVLSSLKVSGVI
What is the function of this protein?
Vacuolar transporter that exchanges protons with Mg(2+), Zn(2+) and Fe(2+) ions.  May control the partitioning of Mg(2+) and Zn(2+) between plant organs.  Could play a role in Zn(2+) accumulation or tolerance.
What are the official names of this protein?
Magnesium/proton exchanger, Mg(2+)/H(+) exchanger, AhMHX, Zinc/proton exchanger, Zn(2+)/H(+) exchanger.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. MHX subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RL17_TRIEI
Sequence: MRHSCRVPKLGKPTDQRRALLRSLATQLIRHGQIKTTKPRAKAVQSEVERMITLAKDGSLAARRRALGYLYDKKLVHSLFNEAQERYGSRNGGYTRVLRTIRRRGDNAEMAIIELI
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HBE2_CAPHI
Sequence: MVHFTTEEKAAVASLWAKVNVEVVGGESLARLLIVYPWTQRFFDSFGNLCSESAIMGNPKVKAHGRKVLNSFGNAIKHMDDLKGTFADLSELHCDKLHVDPPNFRLLGNMILIVLATHFSKEFTPQMQAAWQKLTNAVANALAHKYH
What is the function of this protein?
Beta-type chain found in early embryos.
What are the official names of this protein?
Hemoglobin subunit epsilon-2, Epsilon-2-globin, Hemoglobin epsilon-2 chain, Hemoglobin epsilon-II chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DCDB_MYCUA
Sequence: MLLSDRDLRAEISAGRLGIDPFDDSLVQPSSVDVRLDCMFRVFNNTRYTHIDPAQRQDELTSAVEPTKGDPFVLHPGEFVLGSTLEIFSLPGDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCILKLTSPSEHPYGSSGVGSKYQGQRGPTPSRSYQNFIRST
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RER5_ARATH
Sequence: MKPTTNGGLLASQSSSSFSFPRFRGQLPIIFSANNNQKKKNLPNPNVVTLCLHSHSNVSSSQIAVTRRAILVAPPLLAAAASLFLSISSAASAETSAESVALPPVATAPPPPPVEKEEAITSRIYDASVLGEPMAVGKDKKRVWEKLLNARIVYLGEAEQVPTRDDKVLELEIVRNLRKRCIESDRQLSLALEAFPLDLQEQLNQYMDKRMDGEVLKSYVSHWPVQRWQEYEPLLSYCRDNGVKLIACGTPLKVLRTVQAEGIRGLSESERKLYTPPAGSGFISGFTSFSRSSSLNMNPLTQIVPFGPSSYLSAQARVVEDHTMSQVIVQAVADGGGTGMLVVVTGANHVEYGSRGTGLPARISRKIPKKSQLVVLLDPERQFLRKEGESPVADFLWYSAARPCSRNCFDRAEIARVMNAAGRRRDALPQDIQKGLDLGLVSPEILQNFFDLEQYPLISELTQRFQGFRERLLADPKFLNRLAIEEAISITTTLVAQYEKRKENFFEELDYVITDSVRASVVDFFTVWLPAPTLSFISYADETIGPNSIDALRGLLGSIPDNAFQKSLGGQEWTLSLRIASVIIGGLKLAGVGVVSSFAAVGSSNALYAIRKFIKPELGVGEQAKRSPMLKTALVYGGYLGTSSNIRYQIIAGLIEHRISDELSSQPLLVNMISFVVRVANSYFGTQQWIDLARSTGLQTQKSVTTSNQIPEVASQSTVEYSTTEEASMDDLKNQ
What is the function of this protein?
May play a role in leaf development.
What are the official names of this protein?
Protein RETICULATA-RELATED 5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the RETICULATA family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: GLGB_YEAST
Sequence: MYNIPDNVKGAVEFDPWLKPFADVLSERRYLADKWLYDITHATPDGSYQSLSKFARDSYKSYGLHANPETKEITYKEWAPNAERAFLVGDFNNWDTTSHELKNKDEFGNFTITLHPLPNGDFAIPHDSKIKVMFILPDGSKIFRLPAWITRATQPSKETSKQFGPAYEGRFWNPENPYKFVHPRPKFSESVDSLRIYEAHVGISSPEPKITTYKEFTEKVLPRIKYLGYDAIQLMAIMEHAYYASFGYQVTNFFAASSRFGTPEELKELIDTAHSMGILVLLDVVHSHASKNVEDGLNMFDGSDHQYFHSISSGRGEHPLWDSRLFNYGKFEVQRFLLANLAFYVDVYQFDGFRFDGVTSMLYVHHGVGAGGSFSGDYNEYLSRDRSFVDHEALAYLMLANDLVHEMLPNLAVTVAEDVSGYPTLCLPRSIGGTGFDYRLAMALPDMWIKLIKEKKDDEWEMGSIVYTLTNRRYGEKVVAYCESHDQALVGDKTLAFWLMDAAMYTDMTVLKEPSIVIDRGIALHKMIRLITHSLGGEAYLNFEGNEFGHPEWLDFPNVNNGDSYKYARRQFNLADDPLLRYQNLNEFDRSMQLCEKRHKWLNTKQAYVSLKHEGDKMIVFERNNLLFIFNFHPTNSYSDYRVGVEKAGTYHIVLNSDRAEFGGHNRINESSEFFTTDLEWNNRKNFLQVYIPSRVALVLALKE
What are the official names of this protein?
1,4-alpha-glucan-branching enzyme, Glycogen-branching enzyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RDH54_YEAS1
Sequence: MQIPKYENKPFKPPRRVGSNKYTQLKPTATAVTTAPISKAKVTVNLKRSISAGPTLNLAKKPNNLSSNENTRYFTIMYRKPTTKKHKTWSGDGYATLKASSDKLCFYNEAGKFLGSSMLPSDSDSLFETLFKAGSNEVQLDYELKENAEIRSAKEALSQNMGNPNPPTTSTTETVPSTKNDGGKYQMPLSQLFSLNTVKRFKSVTKQTNEHMTTVPKTSQNSKAKKYYPVFDVNKIDNPIVMNKNAAAEVDVIVDPLLGKFLRPHQREGVKFMYDCLMGLARPTIENPDIDCTTKSLVLENDSDISGCLLADDMGLGKTLMSITLIWTLIRQTPFASKVSCSQSGIPLTGLCKKILVVCPVTLIGNWKREFGKWLNLSRIGVLTLSSRNSPDMDKMAVRNFLKVQRTYQVLIIGYEKLLSVSEELEKNKHLIDMLVCDEGHRLKNGASKILNTLKSLDIRRKLLLTGTPIQNDLNEFFTIIDFINPGILGSFASFKRRFIIPITRARDTANRYNEELLEKGEERSKEMIEITKRFILRRTNAILEKYLPPKTDIILFCKPYSQQILAFKDILQGARLDFGRLTFSSSLGLITLLKKVCNSPGLVGSDPYYKSHIKDTQSQDSYSRSLNSGKLRVLMTLLEGIRKGTKEKVVVVSNYTQTLDIIENLMNMAGMSHCRLDGSIPAKQRDSIVTSFNRNPAIFGFLLSAKSGGVGLNLVGASRLILFDNDWNPSVDLQAMSRIHRDGQKKPCFIYRLVTTGCIDEKILQRQLMKNSLSQKFLGDSEMRNKESSNDDLFNKEDLKDLFSVHTDTKSNTHDLICSCDGLGEEIEYPETNQQQNTVELRKRSTTTWTSALDLQKKMNEAATNDDAKKSQYIRQCLVHYKHIDPARQDELFDEVITDSFTDLKDSITFAFVKPGEICLREQ
What is the function of this protein?
Involved in the recombinational repair of double-strand breaks (DSB) in DNA during mitosis and meiosis.  Has DNA dependent ATPase activity.  Promotes D-loop (displacement loop) formation with RAD51 recombinase.  Modifies the topology of double-stranded DNA during the D-loop reaction to facilitate the invasion of the homologous duplex molecule by the initiating single-stranded DNA substrate.  Required for adaptation from G2/M checkpoint arrest induced by a double strand break, by participating in monitoring the extent of single-stranded DNA produced by resection of DNA ends.  This role is distinct from its roles in recombination.  Promotes colocalization of RAD51 and DMC1 during meiotic recombination.  Involved in crossover interference (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RDH54, RAD homolog 54, Recombination factor TID1, Two hybrid interaction with DMC1 protein 1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LV310_HUMAN
Sequence: MAWTPLLLPLLTFCTVSEASYELTQPPSVSVSPGQTARITCSGDALPKKYAYWYQQKSGQAPVLVIYEDSKRPSGIPERFSGSSSGTMATLTISGAQVEDEADYYCYSTDSSGNH
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 3-10.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: CH60_ECO8A
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA1_CAMJJ
Sequence: MNNIVHKLKTLVLNEAFGGVLLIVCTLLALLVQNGSFSEHYREFLNLKVGFSVGEFELNKPFLLWINDGLISIFFFAIGLELKKEFLHGDFKNPKNIVLPFMAALGGILIPAMLFVLVNIGDAYTLKGWAIPTATDTAFALAILMMCGKHIPSSLKIFLLSLAIFDDVGAILIIAIFYTTKLSIVAFVVAGIAILAMLVLNILGITRKSFYFICSVILWISVLKSGVHATLAGIITAFFIPMQTKNGEAFLEEIYESLKFWLAFVILPLFAFANAGVNLSNIDIGAIFSGVSVGIFLGLFVGKQAGVFLFSYLAIRFKFAALPQGSNLKQLYGVCILTGIGFTMSLFIDGLAYEVSDIFNYADNLAILIASFCSGIWGFIYLKFFATRS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMN_SALTY
Sequence: MSEQIVTPESSTPVVPNKETKINLLDLNRQQMREFFKNLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLTNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDTIRDEIVPINKKYNIETFLGAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKETPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEVIDIKAI
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTU3C_STAAB
Sequence: MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVMEASGQVVFDNLPLLFAVGTALGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAWCYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVVLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGLHHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLRDGVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKVVGGLMLSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVGIVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIKALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGVGQIIPLSEVPDQVFAGKMMGDGVGFIPEKGEIVAPFDGTVKTIFPTKHAIGLESGSGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQGQPLMKVNLAYLKAHAPSIVTPMIITNLENKELVIEDVQDADPGKLIMTVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in alpha- and beta-glucoside transport (By similarity).
What are the official names of this protein?
PTS system glucoside-specific EIICBA component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTPRE_RAT
Sequence: MEPFCPLLLASFSLSLATAGQGNDTTPTESNWTSTTAGPPDPGTSQPLLTWLLLPLLLLLFLLAAYFFRFRKQRKAVVNSNDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRVRSADDCKRFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHCRVILSQLDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQRSATIVMLTNLKERKEEKCYQYWPDQGCWTYGNIRVCVEDCVVLVDYTIRKFCIHPQLPDSCKAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPSHAGPIVVHCSAGVGRTGTFIVIDAMMDMIHSEQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYLYGDTELDVSSLERHLQTLHGTATHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEFTDYINASFIDGYRQKDYFMATQGPLAHTVEDFWRMVWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGDITIEIKSDTLSEAISIRDFLVTFKQPLARQEEQVRMVRQFHFHGWPEVGIPTEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK
What is the function of this protein?
Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+).
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase epsilon, Protein-tyrosine phosphatase epsilon, R-PTP-epsilon.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Note=Predominantly cytoplasmic. A small fraction is also associated with nucleus and membrane. Insulin can induce translocation to the membrane (By similarity). SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm.
Protein: TTL10_MOUSE
Sequence: MALHPQAGRPHRDGSEAQAEAAAQDLGRLPSPSKVGAAVCRIQGLGHRAARRPRRGIGTTSASRVPRPGALMPATRNRPRFIHCRGQPPRTRVSSKRSKRSRIHPCHTEVPGWTHEKQMGSSVKERLRPELSQLDQDADDLEEEEAARLPVTSPDGLLMEGDKQPSPGQGPFFYIGGTNGASIISNYCESKGWQRTQDSHCEDYKLKWCEIKCRDNYCSFREGQQLLFQLPNNKLLTTKIGLLSALREHARTLSKARMLPSTQTKVLKMEEFFPETYRLDIRDERQAFFALFDETQMWICKPTASNQGKGIFLIRSQEEAAALQAKTQSIEDDPIYRKMPFRAPQARVVQRYVQNPLLLDGKKFDVRSYMLIACAMPYMVFFGHGYARLTLSLYNPHSSDLSGHLTNQFMQKKSPLYTLLKESTVWTMEHLNRYINDKFRKTKGLPRDWVFTTFTKRMQQIMSHCFLAVKSKLECKLGYFDLIGCDFLIDENFKVWLLEMNANPALHTNCEVLKAVIPGVVIETLDLALETCQKSLHSQKMLPLLSQRRFVLLYNGETTDLWPRLASSRPLNRLPNPNPNPNPNANPHPHPHPNPHPHPNPHPNANPHPPRPTCEAASSALSSARAAISERPGARKSMPSRGAPVCTPRKSRLSDSSGSSIAESEPSLCSGSLEGSRDTAREPSLGPPEEEREEEQRSTSHRGS
What is the function of this protein?
Polyglycylase which modifies both tubulin and non-tubulin proteins, generating polyglycine side chains of variable lengths on the gamma-carboxyl groups of specific glutamate residues of target proteins (PubMed:19524510, PubMed:18331838, PubMed:19427864).  Involved in the elongation step rather than the initiation step of the polyglycylation reaction (PubMed:19524510, PubMed:18331838, PubMed:19427864).  Polyglycylates alpha-tubulin and beta-tubulin (PubMed:19524510, PubMed:19427864).  Polyglycylates non-tubulin proteins such as nucleosome assembly protein NAP1 (PubMed:18331838).
What are the official names of this protein?
Protein polyglycylase TTLL10, Tubulin--tyrosine ligase-like protein 10.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme.
Protein: METAA_BACAA
Sequence: MPIIIDKDLPARKVLQEENIFVMTKERAETQDIRALKIAILNLMPTKQETEAQLLRLIGNTPLQLDVHLLHMESHLSRNVAQEHLTSFYKTFRDIENEKFDGLIITGAPVETLSFEEVDYWEELKRIMEYSKTNVTSTLHICWGAQAGLYYHYGVPKYPLKEKMFGVFEHEVREQHVKLLQGFDELFFAPHSRHTEVRENDIRGVKELTLLANSEEAGVHLVIGPEGRQVFALGHSEYSCDTLKQEYERDRQKGLNIDVPKNYFKHNNPNEKPLVRWRSHGNLLFSNWLNYYVYQETPYVL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNJB4_HUMAN
Sequence: MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMKISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDHPKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS
What is the function of this protein?
Probable chaperone.  Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).
What are the official names of this protein?
DnaJ homolog subfamily B member 4, Heat shock 40 kDa protein 1 homolog, HSP40 homolog, Heat shock protein 40 homolog, Human liver DnaJ-like protein.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645.