PharMolix/UniProtQA huggingface dataset:
Protein: CHBG_ECOLU
Sequence: MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAIDHAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEEGIALRADRQMVFDLPVNLRTTQGFSSAFYGEEISESLFLQVLDDSSHRGERSLEVMCHPAFIDNTIRQSAYCLPRLTELDVLTSASLKYAIAERGYRLGSYLDV
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_STAAS
Sequence: MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_METNO
Sequence: MSGMPPHIPVLLKEVRSALRLGEGPGIVVDGTFGAGGYTRAILEADPGQRVIAIDRDPTAIATGRGLAAAMAGRLMLVQGRFGELDRLVRAQGIETVDGVVLDIGVSSMQLDQAQRGFSFRQDGPLDMRMESGGTSAADLVNEASEAELADIIYHYGEERRARAVARAILEARRRGRIATTATLAEIVASVVRPEPGSGIHPATRTFQALRIAVNDELGELQRALHAAERILRPGGRLAVVTFHSLEDRIVKQFFSARSGRAVSASRHLPMAEKPAPRSFTLVTKGPIGPSEAEATANPRARSAKLRAGERTDAPIPEPLTALAALAALPSRERGGGRR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNR_BACCE
Sequence: MKEDRRSAPLFPIGIVMDLTQLSARQIRYYEEHNLVSPTRTKGNRRLFSFNDVDKLLEIKDLLDQGLNMAGIKQVLLMKENQTEAVKVKEETKEISKTELRKILRDELQHTGRFNRTSLRQGDISRFFH
What is the function of this protein?
Transcription repressor during nitrogen excess (PubMed:1677938).  On the contrary of the MerR members, which require longer DNA sites for high-affinity binding, GlnR requires a DNA sequence of 17 nucleotides as minimal binding site (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator GlnR.
Protein: IGDC4_HUMAN
Sequence: MARGDAGRGRGLLALTFCLLAARGELLLPQETTVELSCGVGPLQVILGPEQAAVLNCSLGAAAAGPPTRVTWSKDGDTLLEHDHLHLLPNGSLWLSQPLAPNGSDESVPEAVGVIEGNYSCLAHGPLGVLASQTAVVKLATLADFSLHPESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIANAQPWHSGVYVCRANKPRTRDFATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLSLSSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYGLGKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFAPAELKVQAKMESLVVSWQPPPHPTQISGYKLYWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQEKLSDSLDMHSVTGIIVGVCLGLLCLLACMCAGLRRSPHRESLPGLSSTATPGNPALYSRARLGPPSPPAAHELESLVHPHPQDWSPPPSDVEDRAEVHSLMGGGVSEGRSHSKRKISWAQPSGLSWAGSWAGCELPQAGPRPALTRALLPPAGTGQTLLLQALVYDAIKGNGRKKSPPACRNQVEAEVIVHSDFSASNGNPDLHLQDLEPEDPLPPEAPDLISGVGDPGQGAAWLDRELGGCELAAPGPDRLTCLPEAASASCSYPDLQPGEVLEETPGDSCQLKSPCPLGASPGLPRSPVSSSA
What are the official names of this protein?
Immunoglobulin superfamily DCC subclass member 4, Neighbor of punc e11, Protein DDM36, hDDM36.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. DCC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: FTRL_METKA
Sequence: MVEINGVPVEDTFCEAFKGLYARFIVTAADERPLREAAENVAALPATVFGESEAGVERWLDPEETPDGRPGFVAQMWVEYGDDAVKKLEHELGKRIRQGVLVRPTTRVFDACEDPDGYIDTERPIGRCADGYEYTDVRFDREMVHVPIMMGEFLIERRLGYAEGVAGGLVWLFCEDVDAALEAGYRAVEALRDVEGVITPFNVCAAGSKPETIYPDIGPTTNHPYCPTLRDRILDSKVPEGVEAIPEIVINGVSLDVVKRAIGIAIEAATEVDGVVKVSAGNFGGKLGDYRIPLRECIRE
What are the official names of this protein?
Formylmethanofuran--tetrahydromethanopterin formyltransferase-like protein.
What is the protein family that this protein belongs to?
Belongs to the FTR family.
Protein: NS12_CVBON
Sequence: MDIWKPEIKYLRYTNGFNVSELEDACFKFNYKFPKVGYCRVPSHAWCRNQGSFCATLTLYGKSKHYDKYFGVITGFTAFANTVEEAVNKLVFLAVDFITWRRQELNVYG
What are the official names of this protein?
Non-structural protein of 12.7 kDa, ns12.7, 12.7 kDa accessory protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns12.7 protein family.
Protein: HSCA_METPP
Sequence: MALLQISEPGQSPDPHQRRIAVGIDLGTTHSLVAAVRSGVAECLPDDEGRVILPSAVRYLEGGRRAIGFDALAAQAEDPENTIVSAKRFMGRTLTDIDDREKLPYRFVDQPGMVSVATRDGVKTPVEVSAELLATLRFRAEDSFDDELFGAVITVPAYFDDAQRQATKDAAQLAGLNVLRLINEPTAAAIAYGLENGSEGLYAVYDLGGGTFDISLLRLSEGVFEVVATGGDSALGGDDYDHALADWALAGAGLAAETAQDKRAVLVAARAVKEALSSAAEARMQVVLRAGLLDLAVTRVQFEALTKPLTDRTLAAVRKVLRDAKVSKDEVKGVVLVGGSTRMPQIREAVTLYLGRSPLTDLNPDEVVALGAAIQAHQLAGNASGNDLLLLDVTPLSLGLETMGGLVERIIPRNSSIPTARAQDFTTFKDGQTAMAIHVLQGEREQVEYCRSLARFELRGIPPMVAGAARIRVSFQVDADGLLSVTAREQTSGVEAAVTVKPSYGLADEQIARMLQEGFTTAEGDMRDRALREARVETERMVLATRAALAADGDLLADGERAGIEALMRAAEQQALGEDAAAIDAAVKALADGTESFAAERMNRGIRQALAGRRVEEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: FSCG_DICDI
Sequence: MIYILKNFIIILFFLLIILKRIESQSLPSLPSPTIYKSSQCRGDLVYRNVSNRMEDEKIGFTFVQYNGTYQSCVIPCPSPFFTLDEWNKFLYMSLVMGTISFLCGLFLLITYSPIVNKTHNRHTIGVMCMSFGVCLAMCSDMWNFGSNFTDQKSICPSPGQYLTTSNSRCLGSGIVLQFGGVFGFLNWTLLSFDLFMNIKGIITKNYDKYYFVATFIIAIIFTFVPIVNDQYSMSYIGLGCWLGSAVYQLIFFWILLSICLIVSSVFIILILKEIYIIIKQSKQKTSLKGNIRPLLCITVTSFAFFYMFFYYISIVIEGDYYERILNEYTDCLMDPTKDVSECKFPRMSVANEFVFLLCLRLLGIGAFIFYGINKEVKKIWLNSFWFNNSFVGKYIGSKRSMGNDITNSYASKAYSKNYNNNNSINSYNSGLELSIIDMSCNKDDNFKPIIIK
What are the official names of this protein?
Frizzled/smoothened-like sans CRD protein G.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IHFB_ECO8A
Sequence: MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: YCF3_DAUCA
Sequence: MPRSRINGNFIDKTFSIIANILLRIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAHNWLKITRRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: FLOT1_PONAB
Sequence: MFFTCGSNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAESVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLASSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVNHKPLRTA
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
What are the official names of this protein?
Flotillin-1.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Endosome. Membrane, caveola; Peripheral membrane protein. Melanosome. Membrane raft. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (By similarity). Membrane-associated protein of caveola (By similarity).
Protein: TSAD_BACCR
Sequence: MGEYIMEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLAASFQESVIDVLVTKAARAAEAYNVKQLLLAGGVAANKGLRARLEEEFAQKENIELIIPPLSLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPI1_PHANO
Sequence: MSNSTPMSSQGATTRTVTPTSQGGSRTMEVRPQPVLRLSAPSGVLRLRAEPTERRRIQWAEDVVDNEGMGKKSSKVCCIYHKPRAADESSDDESSGSSSDSDSDSEVDNSTARPSSGAGGHRGRAHKHDHGDCEHGHNHGEGSGKPQKRRQRRKPSPNAYEKMPKVKK
What is the function of this protein?
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
What are the official names of this protein?
Type 1 phosphatases regulator YPI1.
What is the protein family that this protein belongs to?
Belongs to the YPI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YE172_YEAST
Sequence: MTVLLEHPLGPDSSRILCLALGKNMASKASCTSLSFLLCMATCSKQLGLNFSYHCSPPSSLILGRILDVSCLERKSFSVLLALRTGEVGLDELHFVICEPNELRLYCNKGRLFKFVLSISFRQEQT
What are the official names of this protein?
Putative uncharacterized protein YER172C-A.
Protein: PNP_NITMU
Sequence: MKIKKSVTYGSHQLTFETGEIARQAHAAIMVSMGDTVVLVTVVGAKSAKQGQDFFPLTVDYQERSYAAGRIPGSFFKREGRPSEKEILTSRLIDRPIRPLFPENFYNEVQVVATVLSSDNEVDADIPAMLGASAALVLSGIPFNGPIGAARIGYINGEYVLNPDTSALKQTQLNLVVAGTRQAVLMVESDAMELSEDVMLGAIVYGHQQMQVAIDAINELADEAGVTAWDWEPPARDPALAVKIAELAENDLRAAFRQKQKQVRSETIDNIWTRVFTELGVEDGEGPDAQAVKEACFALESRIVRSQILDGEPRIDGRDTRTVRPITIRTGLLPRTHGSALFTRGETQALVVATLGTGRDEQKIDALQGDYSERFMLHYNMPPYATGETGRVGTPKRREIGHGRLAKRALVAVLPSPEEFGYSLRVVSEITESNGSSSMASVCGGCLALMDAGVPLKGHVAGIAMGLIKEGNRFAVLTDILGDEDHLGDMDFKVAGTENGITALQMDIKIQGITKEILHAALVQAREGRMHILAIMRQVLPARREDISEHAPRIIKIRINPEKIRDVIGKGGAVIRALTEETGTTIDITDDGTVMIACVNAEGGELAKKRIEDITAEVEVGRVYDGTVLKLLDFGAIVSVLPGKDGLLHISQIANERVNNVGDHLKEGQVVRVKVLEADDKGRLRLSMKAVATDVADNAAT
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMB1_MOUSE
Sequence: MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVSQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLSTCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGSILEGPEPNQLKPLVIQAMPTLIELMKDPSVVVRDTTAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNILPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDFDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA
What is the function of this protein?
Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor.  Acting autonomously, serves itself as NLS receptor.  Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.  Mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5.  In association with IPO7, mediates the nuclear import of H1 histone.  In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones.  Imports SNAI1 and PRKCI into the nucleus (By similarity).
What are the official names of this protein?
Importin subunit beta-1, Karyopherin subunit beta-1, Nuclear factor p97, Pore targeting complex 97 kDa subunit, PTAC97, SCG.
What is the protein family that this protein belongs to?
Belongs to the importin beta family. Importin beta-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus envelope.
Protein: ATP10_YEAST
Sequence: MQGTFKRFYHPTLTRMSFLDKFLKPMMATASPKEYQIKQLVKPIGLTQAPRKSTKYSQGNSLRDMFDSEKTNHRVKELAVEFSKSGLYDVQVFQKTKGKLFIAPVSYWKEDKALFFPHLIGTAMDGTKQQNIEDMLRGKTSIVRLFSTASGDKLSSSYFQGIVDDNKKTDYLTEADARLSLNDSNVQIIEVNLVENAVKSALVKTLARWANRVPSWRQPFYFECSRGQWPFSVREELFCNNVFSGYVFLVDQQLKIRWAACGEATPSEKEALWKFAKRL
What is the function of this protein?
Essential for the assembly of the mitochondrial F1-F0 complex.
What are the official names of this protein?
Mitochondrial ATPase complex subunit ATP10.
What is the protein family that this protein belongs to?
Belongs to the ATP10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: MEP7_COCP7
Sequence: MLLCSMVAALAALATPAFSCALPHLDLPEDNSGLDIKLDSLSNTRVKATITNKADRPLNLLKFNTFFDDGPTEKVGIFKDGNPIKFDGIMRRIQTFDLPISAFVPISPGESIEREFDIASTSDLTVGGAFDILSEGAIPYAEANQTTLTGAMVFKSNALQLKIDGEMAATVARAIQPLDRRSDVHVCRNSAKRKALMKALRNSAHLAGTAASAAYRNPRKVQEYFHTTDRTAVRSVAARLKAISRESGSTRNGATRYACEDHWNRCEPGVLAYTLPSHNLVVNCPSFYNLPALTNRCHGQDQATTVLHEFAHAPGVHEPFCKDHAYGYRSIRRLSTRLALNNADSFSLFANGRFRRRFRVIST
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine.  May be involved in virulence (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog MEP7, Deuterolysin MEP7, Metalloproteinase 7.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_PYRCJ
Sequence: MSAVVQREALLKKIDEALKSGKKRRFRQSVELIVVLRGIDLSKPENRINLLVELPHPPKLNKIAAFAHGAFETQAKNAGVDAVITRQEVEGLAGNKRAIRKLAKQYDFFIAPPDLMPLLGRVIGPIFGPRGKMPEVVPPNVDVKTVVERLRRVVRVRLRNEPVIKVRVGAEGQKPEEILTNILAVLEELNRKFPLRQYLRDIYIKKTMSPPVRIKPAEVLAR
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: EFTS_STAAE
Sequence: MATISAKLVKELREKTGAGMMDCKKALTETDGDIDKAIDYLREKGIAKAAKKADRIAAEGLVHVETKGNDAVIVEINSETDFVARNAGFQELVKEIANQVLDTKAETVEALMETTLPNGKSVDERIKEAISTIGEKLSVRRFAIRTKTDNDAFGAYLHMGGRIGVLTVVEGSTDEEAARDVAMHIAAINPKYVSSEQVSEEEINHEREVLKQQALNEGKPENIVEKMVEGRLRKYLQEICAVDQDFVKNPDVTVEAFLKTKGGKLVDFVRYEVGEGMEKREENFADEVKGQMK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_XANOM
Sequence: MSDSFYRYDVIVIGGGHAGTEAALASARAGAHTLLLTHTIETVGAMSCNPAIGGIGKGHLVKEIDALGGAMAHAADLAGIQWRTLNASKGPAVRATRCQADRNLYRTAIRCIVQAQPKLTVFQAAVDDLIIHNGTCEADSVRGVITQTGLRFEAPSVVLTAGTFLAGKIHVGDTQYAAGRLGDPPATTLAARLRERPFAIDRLKTGTPPRIDGRTLDYGVMGEQPGDDPLPVMSFMGQVSDHPRQVSCWITQTTEQTHDIIRNALHRSPLYSGQIEGIGPRYCPSIEDKVVRFAEKTSHQIFVEPEGLDVAEIYPNGISTSLPFDVQLALVRSIHGFAQAHITRPGYAIEYDFFDPRGLKASLETKAVGGLFFAGQINGTTGYEEAAAQGLLAGLNAARHVHGLPAWSPRRDEAYLGVLVDDLITHGTTEPYRMFTSRAEYRLQLREDNADARLTGAGREMGLVDDARWARFSAKQEAVQRETARLSALWATPGNALGREVADALGVTVSRETNVLDLIKRPELNYATLMRVPTLGPGVDDAQVAEQVEISVKYTGYLDRQRDDIARQQRHETTPIPEGFDYAGVRGLSIEVQQKLEHVRPQHIGQAQRIPGMTPAAISLLLVHLERARRHRVA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_I33A0
Sequence: MKAKLLVLLYAFVATDADTICIGYHANNSTDTVDTIFEKNVAVTHSVNLLEDRHNGKLCKLKGIAPLQLGKCNITGWLLGNPECDSLLPARSWSYIVETPNSENGACYPGDFIDYEELREQLSSVSSLERFEIFPKESSWPNHTFNGVTVSCSHRGKSSFYRNLLWLTKKGDSYPKLTNSYVNNKGKEVLVLWGVHHPSSSDEQQSLYSNGNAYVSVASSNYNRRFTPEIAARPKVKDQHGRMNYYWTLLEPGDTIIFEATGNLIAPWYAFALSRGFESGIITSNASMHECNTKCQTPQGSINSNLPFQNIHPVTIGECPKYVRSTKLRMVTGLRNIPSIQYRGLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAINGITNKVNSVIEKMNTQFTAVGKEFNNLEKRMENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDLNVKNLYEKVKSQLKNNAKEIGNGCFEFYHKCDNECMESVRNGTYDYPKYSEESKLNREKIDGVKLESMGVYQILAIYSTVASSLVLLVSLGAISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: DNAJ_ECO57
Sequence: MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLNEKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.