PharMolix/UniProtQA huggingface dataset:
Protein: SNAG_ARATH
Sequence: MSSDPDKMMSKADKMTKLTLTRWSADWRGATELYEQAANGFRASNKYEKAKVALEKASKGQEMQASPWDAAKHMESAAALAQKLSIWNEVADFYRKASELYVECGRAQPASDALGKAARALEDVKPDDAIQLYTDACEILEEDGRDQMAFDLYRACANVYIKLEKFTDAATFFLRLGVAADKCDATNSQCKAYLSAIILYLYAHDLQQAEKCYNDCSQIDAFLKSDQSRSASRLLTAYNEGDIEEIKKVASASTVSNLDHMIIKLARKLPTGDVTAIQMNTNDDLDEDDLT
What is the function of this protein?
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.  Binds to SNARE complex and then recruits NSF to disassemble it (By similarity).
What are the official names of this protein?
Gamma-soluble NSF attachment protein, Gamma-SNAP, N-ethylmaleimide-sensitive factor attachment protein gamma.
What is the protein family that this protein belongs to?
Belongs to the SNAP family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: RL24_ECOUT
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNATTGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: KHSE_EDWI9
Sequence: MVKIYAPASIGNVSIGFDVLGAAVTPLDGTLLGDCVSIAASSHFSLHCHGRFVDSLPSTVQENIVYQCWQRFCEVTGRELAVEMVLEKNMPIGSGLGSSACSVVAALAALNRFAGEPLDAHRLLMLMGELEGRISGSVHYDNVAPCYLGGLQLMLEAQEIISQPVPCFDEWLWVMAYPGIKVSTAEARAILPPHYSRGDCVRHGRHLAGFIHACHTRQPSLAAALMQDVIAEPYRCGLLPGFADARRAAGELGALACGISGSGPTLFAVCDDLTAAQAVAQWLAQHYLQNEQGFVHICRLDSAGARQLG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_BORDL
Sequence: MAKKSMIVKALRKPKYKTRQKNRCKLCGRPKGYMRDFSMCRICFRNHASAGLIPGVSKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: COQ7_NITEU
Sequence: MLNIDKLIIGFDSALRTLLAPANTLRPVPGKDLPENELSEIEKRESAALMRINHVGEVCAQALYQGQALTARNDRVRQALDQAAREETEHLAWTERRIAELGGRKSFLNPLWYGGSFTLGLVAGVLGDKWNLGFLAETERQVEAHLADHLQRLPHQDVRSRAIVTQMKVDEACHATMAVSHGGGQLPAPVKVAMKFSSRIMTRTAYWV
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CYAY_SALAR
Sequence: MNDSEFHRLADTLWLTIEERLDNWDGDSDIDCEINGGVLTLSFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGATFWDLLEQAATQQAGEAVSFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: TGT_PSYA2
Sequence: MQFVLHKTASGVTRARRGTVHLNHGDVQTPAFMPVGTYGTVKGMLPRDIEAIGADIILGNTFHLWLRPGTDIIDKFGGLHKFMHWDKPILTDSGGFQVFSLGAMRKITEEGVTFKSPIDGAKVFLSPEKSMQIQYSLNSDIVMQFDECTPYPATHDEAKKSLELSLRWGQRCVDEHKKLGSTNALFGIIQGSMYADLRKQSLEGLLEIGFDGYAIGGLSVGEPKEEMIDVLDYIANDMPADKPRYLMGVGKPEDLVEGVRRGVDMFDCVMPTRNARNGHYFVTGDVDNAGVVRIRNSQYRTDEGPLDPECDCYTCQNFSRAYLSHLNKCKEMLGAQLATIHNLRYYQRLMQGIRDAIEQDKFDEFVTEFYSKRGQTVPELNLR
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ODR4_PONAB
Sequence: MGRTYIVEETVGQYLSNIGLQGKAFVSGLLIGQCSSQKDYVILATRTPPKEEQSENLKHLKAKLDNLDEEWATEHACQVSRMLPGGLLVLGVFIITTLELANDFQNALRRLMFAVEKSINRKRLWNFTEEEVSERVTLHICASTKKKIFCRTYDIHDPKSSARPADWKYQSGLSSSWLSLECTVHINIHIPLSATSVSYTLEKNTKNGLTRWAKEIENGVYLINGQVKDEDCDLLEGQKKSRGNTQATSHSFDVRVLTQLLLNSDHRSTATVQICSGSVNLKGAVKCRAYIHSSKPKVKDAVQAVKRDILNTVADRCEILFEDLLLNEIPEKKDSEKEFHVLPYRVFVPLPGSTVMLCDYKFDDESAEEIRDHFMEMLDHTIKIEDLEIAEETNTACMSSSMNSQASLDNTDDEQPKQPIKTTMLLKIQQNIGVIAAFTVAVLAAGISFHYFSD
What is the function of this protein?
May play a role in the trafficking of a subset of G-protein coupled receptors.
What are the official names of this protein?
Protein odr-4 homolog.
What is the protein family that this protein belongs to?
Belongs to the ODR-4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LLOS_PICGL
Sequence: MAFVSIAPLASRCCVHKSFVSSREVKPLCRTIPTLGRCRRGKTVTPSISMCWTATVLDDGVQRRIANHHSNLWDDSFIQSLSTPYGETSYLERADKLIGEVKEIINSISVEDGELITPLNDLIQRLSIVDIIERLGIDRHFKNEIKSALDYVYSYWNEKGIGCGRECVITHLNSTALGLRTLRLHGYPVSSDVLEQFKDQNGQFACSAIQTEGEIKSVLNLFRASLIAFPGEKVMEEAEIFSTIYLKEALLTIPVCSLSREIAYVLEHGWHTNLPRLEARNYIDVFGQDPIYGTPNIKMTQKLLEIAKLEFNIFHSLQQKELKHLSRWWKDSVFSQLAFPRHRHVEYYTLASCIDIDPQHSSFRLGFAKISHLGTVLDDIYDTFGTMDELELFTAAVKRWHPSATKWLPEYMKGVYMMLYETVNEMAREADKSQGRDTLNYARQAWEAYIDSYMKEAKWISSGFLPTFEEYLDNGKVSFGYRIGTLQPILTLGTPFPHHILQEIDFPSSLNDLACSILRLKGDILTYQAERSRGEKSSCISCYMKDNPGSTEEDAVAYINGMVNKSLKELNWEFLRPDSNAPITSKKHAFDILRAFYHLYKHRDGFSVARNEIRNLVKTTVIEPVPL
What is the function of this protein?
Terpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens (PubMed:21385377).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to (R)-linalool (PubMed:21385377).
What are the official names of this protein?
(R)-linalool synthase, chloroplastic, Terpene synthase TPS-Lin, PgTPS-Lin.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LEAP2_MOUSE
Sequence: MLQLKLFAVLLTCLLLLGQVNSSPVPEVSSAKRSRRMTPFWRGVSLRPIGASCRDDSECITRLCRKRRCSLSVAQE
What is the function of this protein?
Has an antimicrobial activity.
What are the official names of this protein?
Liver-expressed antimicrobial peptide 2, LEAP-2.
What is the protein family that this protein belongs to?
Belongs to the LEAP2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPX_ALKEH
Sequence: MTDKDNGRDDGGKLLYCSFCGKSQHEVRKLIAGPSVFVCDECVELCNDIIREELQEQSSSAGAGLPRPHEINQVLDEFVVGQEHAKKVLSVAVYNHYKRLEAGSRKDEVELSKSNILLIGPTGSGKTLLAETLARMLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVYIDEIDKVSRKADNPSITRDVSGEGVQQALLKLIEGTTASVPPQGGRKHPQQEFLQVDTGGILFICGGAFAGLDKVIQDRSEKGGIGFSAEIKSKDEKRSVGETLQDVEPEDLVKYGLIPEFVGRLPVVATLEELDEQALVEILSAPKNALVKQYQKLFEMEGVELEFREDALRAVARKAMDRKTGARGLRTILEHVLLDTMYDLPSMENVEKVVVDDAVIRGETRPYIIYGNQEQSRAASSD
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: METAS_SHESM
Sequence: MPVKIPDHLPAAGILESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHTSIDHMNTFYRDFEDVRHKNYDGLIITGAPLGQIDFEEVTYWDHIREIIDWSQQHVTSVLFLCWAAHAGLYHLYGLNRKILQQKRSGVFVHRRTCQHFPLLRGFDDEFFAPHSRFAEMDIEELKQHPELQVLAESDEAGAYLVLSRNNRNLFVMGHPEYQKSTLNDEYHRDLAQGLNPNVPQNYYRNDDPQADAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMTAMTPWESQ
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_ACAM1
Sequence: MHRTFLFSKIHHCTLTETNLEYVGSISIDQTLLDAAGIVPYEQVQVVNMNNGERLVTYAIPAPADSGAVELNGAAARLGTRGDRVIIMTYAQLTSEEIEGFEPRVVLVDQENRVIEDAPVVNASTPELCLT
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_MYCAP
Sequence: MPTTNQLVVNGRENKVRKQNAPALNLSFNTLTKSARKLPAPFKRGVCTRVATMTPKKPNSASRKYARVKLSNGMEITAYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGTQDLAGVANRKQGRSLYGAKKEKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: CT54_CONVE
Sequence: MRCLPVFVILLLLIASAPSVDARPKTKDDVPLASFHGNAERTLLNILRDGDNCCIDKQGCCPWG
What are the official names of this protein?
Conotoxin VnMRCL-04.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_FERNB
Sequence: MYQKIKGTEDLYGDEMKYWYWIEKKAKDLAIRYGYGEIRTPIFEETKLFIRSVGQDTDIVQKEMYTFEDKGGRSITLRPEGTAPVVRAFVEDGMIAQGFPQKYFYIGPMFRYERPQSGRQRQFHQFGAEIFGSSSAIADAELIIFADRLMKEIGLVDYQIHINSLGDIEDRVKYREALKEYYAQHLENLCDDCKVRYEKNVLRLLDCKVDIEYTKNAPKITDYLGENSRKHYEELKALLDSVGIKYIENPRLVRGLDYYNRTVFEIHHQKLGAMSAIAGGGRYDGLIKEIGGKDVPALGFATGIERLILALKAENVLVDEIETNVVYIAYLGGFDVKAEAIRLSEELRREGIPVGLELMERGLSAQLKNAARVGAKFTIIVGESELERNIVLVKNMETGEQLEFERSFVVSGIKDMITEMQ
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY2_STRM6
Sequence: MTKIYSSIAVKKGLYTLFLLFIYVLGSRITLPFVDLNSKDFLGGSTAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSYSKKLGLSSTAIEIQDRRKMYLTLLIAVIQSLAVSLSLPVQSSYSAILVVLMNTLLLIAGTFFLVWLSDLNASMGIGGSIVILLSSIVLNIPQDVIETFQTVHIPTGIIVLLALLTLVFSYLLAIMYRARYLVPVNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHAGLAALSKEFMVGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGEDTSRFINGLVLRFSVIGGLFNVIMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEVKALRLNETYKPLI
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins.  The central subunit of a protein translocation channel.
What are the official names of this protein?
Accessory Sec system protein translocase subunit SecY2.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PEB1A_CAMJJ
Sequence: MVFRKSLLKLAVFALGACVAFSNANAAEGKLESIKSKGQLIVGVKNDVPHYALLDQATGEIKGFEVDVAKLLAKSILGDDKKIKLVAVNAKTRGPLLDNGSVDAVIATFTITPERKRIYNFSEPYYQDAIGLLVLKEKNYKSLADMKGANIGVAQAATTKKAIGEAAKKIGIDVKFSEFPDYPSIKAALDAKRVDAFSVDKSILLGYVDDKSEILPDSFEPQSYGIVTKKDDPAFAKYVDDFVKEHKNEIDALAKKWGL
What is the function of this protein?
Common antigen and a major cell adherence molecule.  Most probably involved, with PEB1C, in a binding-protein-dependent transport system for an amino acid.  May be involved in binding to intestinal cells.
What are the official names of this protein?
Major cell-binding factor, CBF1, PEB1.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Cell surface.
Protein: RL14_PSEPF
Sequence: MIQTQSMLDVADNSGARRVMCIKVLGGSHRRYAGIGDIIKVTVKEAIPRGKVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLNNKQEPIGTRIFGPVTRELRTEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NDK_HELAN
Sequence: MEQTFIMIKPDGVQRGLVGEIIGRFEKKGFTLKGLKLLTVDQAFAEKHYADLSAKPFFNGLVEYIISGPVVAMVWEGKNVVTTGRKIIGATNPAESPPGTIRGDFAIDIGRNVIHGSDAVESAKKEIGLWFPEGVANWSSSLHPWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: IGF2_CAVPO
Sequence: MGISMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSASLAVLPDNFPRYPVGKFFQYDTWRQSTQRLRR
What is the function of this protein?
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion.  Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
What are the official names of this protein?
Insulin-like growth factor II, IGF-II, Somatomedin-A.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PKHF2_HUMAN
Sequence: MVDRLANSEANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSAGDMATCQPARSDSYSQSLKSPLNDMSDDDDDDDSSD
What is the function of this protein?
May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport.  Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467).
What are the official names of this protein?
Pleckstrin homology domain-containing family F member 2, PH domain-containing family F member 2, Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains, EAPF, PH and FYVE domain-containing protein 2, Phafin-2, Phafin2, Zinc finger FYVE domain-containing protein 18.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum. Note=Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots (PubMed:19995552). May translocate to the endoplasmic reticulum in the early phase of apoptosis (PubMed:18288467).
Protein: AROQ_BACC3
Sequence: MKKVLLVNGPNLNRLGVREVNVYGKGTLATLEADMKQEAEAMGVELECFQSNHEGAIIDRIHEAEDIYEGIILNPGAFTHYSYAIRDAIASISIPVIEVHISNIHQRESFRHESVTAAVCAGQIVGFGFYGYKLALFALMEKLREA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: DART_THEA5
Sequence: MPQQGLAYPVPTLIYHITHLNNLQGILQRGGLLPYSQRPPTQQNVAYGHIQAHRAQVVVPVGPRGKLHDYVPFYFCPRSPMLYAIHTQQTDYQGDQRPILHLVSSAQKVAEARIPFVFTDRHAAVQYVCFFHKLEHLKALDWQAIQASYWANVREKKQAEFLVKDFFPWELVEEIGVIDKTIQAQVESILAQFPDLHHPPVRVRRSWYYKKRLCSASCEATF
What is the function of this protein?
Toxic component of a hybrid type II/IV toxin-antitoxin (TA) system.  Its toxic effect is neutralized by cognate antitoxin DarG.  ADP-ribosylates ssDNA on the second thymidine of the consensus sequence 5'-TNTC-3'; the protein does not auto-modify.  Has no activity on dsDNA in vitro.  This leads to a decrease in DNA replication.  Upon expression in E. coli inhibits cell growth, colony formation and induces the SOS response.  Expression leads to bacteriostasis; however if cells grow over an hour in the presence of toxin, growth is no longer restored on antitoxin-inducing plates (PubMed:27939941).  In E. coli ADP-ribosylates genomic DNA (gDNA), which induces RecA expression (a marker for DNA damage) (PubMed:34408320).
What are the official names of this protein?
DNA ADP-ribosyl transferase, DarT, Toxin DarT.
What is the protein family that this protein belongs to?
Belongs to the DarT ADP-ribosyltransferase family.
Protein: AGP17_ARATH
Sequence: MTRNILLTVTLICIVFITVGGQSPATAPIHSPSTSPHKPKPTSPAISPAAPTPESTEAPAKTPVEAPVEAPPSPTPASTPQISPPAPSPEADTPSAPEIAPSADVPAPALTKHKKKTKKHKTAPAPGPASELLSPPAPPGEAPGPGPSDAFSPAADDQSGAQRISVVIQMVGAAAIAWSLLVLAF
What is the function of this protein?
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death.
What are the official names of this protein?
Lysine-rich arabinogalactan protein 17, Lys-rich AGP 17.
What is the protein family that this protein belongs to?
Belongs to the lysine-rich AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: FADX_MOMCH
Sequence: MGGRGAIGVLRNGGGPKKKMGPGQGLGPGERITHARPPFSISQIKKAIPPHCFQRSLRRSFSYLLSDIALVSAFYYVADTYFHRLPHPLLHYLAWPVYWFCQGAVLTGMWGIAHDCGHHAFSDYQLVDDVVGFLIHSLVFVPYFSFKISHRRHHSNTSSVDRDEVFVPKPKAKMPWYFKYLTNPPARVFIIFITLTLGWPMYLTFNISGRYYGRFTSHFDPNSPIFSPKERVLVHISNAGLVATGYLLYRIAMAKGVGWLIRLYGVPLIVLNACVVLITALQHTHPSFPYYDSTEWDWLRGNLVTVDRDYGPIMNRVFHHITDTHVVHHLFPSMPHYNGKEATVAAKRILGEYYQFDGTPIWKAAWREFRECVYVEPDEDDGATSGSSSKGVFWYHNKL
What is the function of this protein?
Converts linoleic acid to alpha-eleostearic acid (18:3(9Z,11E,13E)) and alpha-linolenic acid to alpha-parinaric acid (18:4(9Z,11E, 13E, 15Z)).  Converts a single cis double bond at carbon 12 to two conjugated trans bonds at positions 11 and 13.
What are the official names of this protein?
Delta(12) acyl-lipid conjugase (11E,13E-forming), MomoFadX.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DAPH_STRR6
Sequence: MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLGNVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEIGDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAEPVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQTQQKTALEDALRTL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: RS13_ERWT9
Sequence: MARIAGINIPDHKHTVIALTAIFGIGKTRSQSICASTGIAENVKISELSEEQIDILRDAVAKFVVEGDLRREVTLSIKRLMDLGCYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: YIDD_BACFN
Sequence: MKRLLSYILLLPIYFYRACISPMTPPSCRFTPTCSQYAIEAIKKHGPFKGLYLAVRRILRCHPWGGSGYDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SOX6_HUMAN
Sequence: MSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINQRLKGLSDRFGRNLDTFEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN
What is the function of this protein?
Transcription factor that plays a key role in several developmental processes, including neurogenesis, chondrocytes differentiation and cartilage formation (Probable).  Specifically binds the 5'-AACAAT-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis.  Required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes: SOX5 and SOX6 cooperatively bind with SOX9 on active enhancers and super-enhancers associated with cartilage-specific genes, and thereby potentiate SOX9's ability to transactivate.  Not involved in precartilaginous condensation, the first step in chondrogenesis, during which skeletal progenitors differentiate into prechondrocytes.  Together with SOX5, required to form and maintain a pool of highly proliferating chondroblasts between epiphyses and metaphyses, to form columnar chondroblasts, delay chondrocyte prehypertrophy but promote hypertrophy, and to delay terminal differentiation of chondrocytes on contact with ossification fronts.  Binds to the proximal promoter region of the myelin protein MPZ gene, and is thereby involved in the differentiation of oligodendroglia in the developing spinal tube.  Binds to the gene promoter of MBP and acts as a transcriptional repressor (By similarity).
What are the official names of this protein?
Transcription factor SOX-6.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.