PharMolix/UniProtQA huggingface dataset:
Protein: FASTK_MOUSE
Sequence: MLRILLSAQTSPARLSGLLLIPPVQPCCLGPSKSGDRPFGGGPVQGLQRLLEQARSPGELLRWLSQNPTKVRAHHYPVALRRLGQLLVSQPRPSPVEQATLQDLSQLIIRNCPSFDVHTIHVCLHLAVLLGFPSDGPLLCALEQERRSRLPPKPPSPHRPAIYGGQRLEVALSCPRFLQYPRQHLIRSLAEARPEELTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQEAQLNSKVVQKLVLPFGRLNYMPLEQQFMPCLERILAREAGVAPLATVNILMSLCQLQCLPFRALQFVFSPSFINHINGTPPSLIVRRYLSLLDTAVELELPGYQGPRLPQRQRVPIFPQPLITDRARCKYSHKDMVAEGLRQLLGEENYRQNLTVPPGYCTDFLLCVSSSGAVLPMRTQDPFLPYPPRSCQQDQANFNSTTQDPAQRVVLMLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLPLPFEELESQRGLPQLKSYLRQKLQALGFRWGPEGG
What is the function of this protein?
Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor (By similarity).  Required for the biogenesis of some mitochondrial-encoded mRNAs, specifically stabilizes ND6 (NADH dehydrogenase complex subunit 6) mRNA, and regulates its levels.
What are the official names of this protein?
Fas-activated serine/threonine kinase, FAST kinase.
What is the protein family that this protein belongs to?
Belongs to the FAST protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Note=Colocalizes with mitochondrial RNA granules.
Protein: NADK_STAAN
Sequence: MRYTILTKGDSKSNALKHKMMNYMKDFRMIEDSENPEIVISVGGDGTLLQAFHQYSHMLSKVAFVGVHTGHLGFYADWLPHEVEKLIIEINNSEFQVIEYPLLEIIMRYNDNGYETRYLALNEATMKTENGSTLVVDVNLRGKHFERFRGDGLCVSTPSGSTAYNKALGGALIHPSLEAMQITEIASINNRVFRTVGSPLVLPKHHTCLISPVNHDTIRMTIDHVSIKHKNVNSIQYRVANEKVRFARFRPFPFWKRVHDSFISSDEER
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOXC1_XENTR
Sequence: MQARYSVSSPNSLGVVPYLSGEQSYYRAAAAAAAAGGGYTGMAAPMSMYSHPAHEQYQAGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVVKDATKEDKDRLLKEHHGSQPAAAQQQRQQQQGQAQAEQDSGSQPVRIQDIKTENGTSSPPQAMSPALSTVPKIESPDSSSSMSSGSPHSIPSNRSMSLEAAESHHPHQQHHHSQGFSVDNIMTSLRGSPQGSGELPSPLISSSRTGIAPSSLLTYSPGQGSIYSPPCSQGTSSGGGAGTYHCNMQAMSLYSGDRSGHLTPANTPAATTVEDTLPDYSITTTTTSALSHGNQEHPHQGRLPSWYLNQAGDLGHLAGATYPGQQQNFHSVREMFESQRLGLNSSPVNGNSSCQMSFPPSQSLYRTSGAFVYDCSKF
What is the function of this protein?
DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development.  Acts either as a transcriptional activator or repressor.  Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes.  Upon DNA-binding, promotes DNA bending.  Required for cell viability and resistance to oxidative stress in the eye.  Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1-mediated signals.  Involved in epithelial-mesenchymal transition (EMT) induction by increasing cell proliferation, migration and invasion.  Involved in chemokine-induced endothelial cell migration.  Plays a role in epidermal keratinocyte terminal differentiation.  Essential developmental transcriptional factor required for mesoderm-derived tissues formation, such as the somites, skin, bone and cartilage.  Plays a role in the development and maintenance of mesenchymal niches for haematopoietic stem and progenitor cells (HSPC).  Plays a role in corneal transparency by preventing both blood vessel and lymphatic vessel growth during embryonic development in a VEGF-dependent manner.  Plays a role at the gastrula stage for expression of several mesodermal and endodermal genes.  At the late neurula stage, regulates expression of adhesion genes to maintain cell adhesion in the mesodermal germ layer.
What are the official names of this protein?
Forkhead box protein C1.
What are the subcellular locations of this protein?
Nucleus.
Protein: INT6_DANRE
Sequence: MPILLFLIDTSASMNQRTYLGTTYLDIAKGAVEIFMKLRARDPASRGDRYMLVTFDDPPYGVKAGWKENHATFMSELKNLQASGLTTLGHALRAAFDLLNLNRLVSGIDNYGQGRNPFFLEPSVIITITDGNKLTHSSGVAEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVAVPDSEQLGSVPTDESAITQMCEVTGGRSYCVRTQRMLNQCLESLVQKVLSGVVIHFEKTGPDPPVIGEDGLVDPARPLTSFSPQPWHSCHKLIYVRPNPKTGVPVGHWPISESFWPDQNSPTLPPRSAHPVVRFSCVDCEPMVIDKLPFDKYELEPSPLTQYILERKSPHMCWQVFVNCSGKHSDVAHPFGYLKASTTLTCVNLFVMPYNYPVLLPLLDDLFKVHKLKPNLKWRQSFEMYLKSMPPYYLLPLKKALRMMGAPNLISDNMDCGLSYSVISYLKKLSQQAKIESDRLIVSVGKKPPPETGIKVKNHSNALSLAHRRDFKQLLQGITGEVPLRLIDMNFKEFAGFQIALLNKDLKPQAYRNAYDIPRRNLLDQVTRMRSNLLRTTQKLIRGQDDDSLHSIPVGQMGNYQEYLKMMPSPLREIDPDQPKRLHTFGNPFKQDKKGMMIDEADEFVTGPQNKKRGNTGDLNSGTALKRRRSMSPLLRRPQTPPIITNHVLGKGPTGTQGQQGIIKPIPLHKGAEGNNVGGTESNGERVAGTDAGDCWPGEVDGESGEPAPVEDREDAAAPDGEEEILALENCLDDRSPDHTQNCEELSPPGQEGEMEVNEGDTPAQGTIVMIPLEGSNAELRTRVIKEVRKPGRNYEAIFRLLEEVKGPVSVQRYFIHHAIKEAARFKKRMLIQQLETALEEIEDRQMLPAQINNIHSR
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 6, Int6, Protein DDX26B.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL1_GEOKA
Sequence: MPKRGKKYLEALKLVDRSKAYPIAEAIELVKKTNIAKFDATVEVAFRLGVDPKKADQQIRGAVVLPHGTGKVARVLVFAKGEKAKEAEAAGADYVGDAEYINKIQQGWFDFDVVVATPDMMGEVGKLGRILGPKGLMPNPKTGTVTFDVAKAVQEIKAGKVEYRVDKAGNIHVPIGKVSFDNEKLAENFAAVYEAILKAKPAAAKGTYVKNVTITSTMGPGIKVDPSTVAVAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MATK_PSAJU
Sequence: MEKFEGYSEKHKSRQQYFVYPLLFQEYIYAFAHDYGLNGSEPVEIVSCNNKKFSSLLVKRLIIRMYQQNFWDKSVNHPNQDRLLDYKNYFYSEFYSQILSEGFAIVVEIPFSLRELSCPKEKEIPKFQNLRSIHSIFPFLEDKFLHLDYLSHIEIPYPIHLEILVQLLQYRIQDVPSLHLLRFFLNYYSNWNSFITSMKSIFLFKKENKRLFRFLYNSYVSEYEFFLLFLRKQSSCLPLASSGTFLERIHFSRKMEHFGIMYPGFSRKTLWFFMDPLMHYVRYQGKAILASKGTFFLKKKWKCYLINFWQYYFCFWTQPRRIHINQLANSCFDFLGYLSSVPKSPLLVRNQMLENSFLIDTRMKKFDTIVPATPLIGYLSKAEFCTGSGHPISKPIWTDLSDWDILDRFGRICRNLFHYHSGSSKKRTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSAFLEEFFTEEEQVFSLMFTKTTLFSFCGSHTERIWYLDIIRINDLVNPLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PURA_HAMD5
Sequence: MGKNIVVLGAQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLISKGKKTVLHLIPSGILRNNTINIIGNGVVLEPHALIKEIKELEMQGVPVRNRLLLSAACPLILPYHVALDNEREKARGSKAIGTTGRGIGPAYEDKVARRALRLGDLFNQITFESQLKEVIEYHNFQLVHYYKAEPVHYQRVVESIWGIADILKNMVIDVTQVLSQAREKAENLLFEGAQGTFLDIDHGTYPYVTSSNTTAGSVATGAGFGPLYIDYILGIVKAYSTRVGAGPFPTELNDETGNFLRDKGHEYGATTGRSRRTGWLDAVSLRQAIQMNSLSGLCMTKLDVLDGLKTVKICVRYKRTDGTETMSTPITSAEWAEVEPIYEALPGWKESTFGIKEKSQLPQTALNYIKRVEELTGVPVDIISTGPDREETIILRHPFDEMIKK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_AERPE
Sequence: MVNSFEKSRFLLVKKLLEGEPLTPGEAAQLAQAMLDPSFDNSLKAAALAALRVRGEQPGEVVGFARALRDRAVRVEYGGEVLLDTAGTGGDGLSTLNASTAAALVAASLGVPTAKHGNRSFSSKSGSADVMEMLGYNINHRADRAVRMLSTLGFTFLYAPNYHPAMKAVVPVRRKLATRTIFNLVGPLANPAFNNVQVIGVARRSLMPVIASAASLLGYDAVLVVHGDPGMDEVSVTGETKILEVRRGRIEEYSITPEDLGLPITGLKELRVANAVESAERVRRALSGRGRRSDEAFIAANAAAALYVAGFEKDLKGAAEAAVQAIREGRPAALLEKAVKASLGM
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: HISP_LACLM
Sequence: MENQNQVKRNLKQRHITMIALGGTIGTGLFLTSGATISQAGPWGAVLAYCFIGIMVYFVMTSLGEMATYLPTSGSFSDYGGRYVDPAFGFALGWNYWLNGAITIAVDLTTAGLITQFWFPHLPSWIFSGIATVLIFIINVMAVGAFGETEYWLSTIKVITIVLFLAIGLLTIFGVLGQGNVDVVANLTAGNHGFVGGISGFVGVLLIAGFSFQGTEMLGITAGESEDPGKTIPKAMNSIFWRILLFYIFSIIVIAAIINFKDPRLLNPSSTAVMSPFTIVFKNIGFAVAASVMNAVILTSVISSANSVMYASTRILYSLGQEKGAPKFFGRTAKNGIPFYALLATTIICFIAFLTGIFGTQIYLFLIDLSSLTGFLAWLGISVSHIRFRRAYIAQGKKLEDLPYKAKWFPFGPIVALLMTGAIAINLDPAMLFSEHWGEGLALYAAIPIFIVLYFGYKWKYNTKIIPLEEVDLSREK
What is the function of this protein?
Involved in histidine uptake.  Has low affinity for arginine and lysine.  Plays no significant role in the excretion of accumulated histidine.
What are the official names of this protein?
Histidine permease HisP.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y015_SIFVH
Sequence: MVDVETVETKYKIILDTQSNYVLMEGRLKVEVRIKGKPIIYEVQEVRNMGYLIDITELDIADTKQRIDSKLCERRYKYVNSLKNLEKFINFVGAEIEVK
What are the official names of this protein?
Uncharacterized protein 15.
Protein: MGSA_VIBA3
Sequence: MQKTTRTMPTHKNIALVAHDHFKPELLRWVKENKEKLQKHFLYATGTTGSLLSKETGLAIKSMISGPMGGDQQLGALISEGKIDMMIFFWDPLNAVPHDPDVKALLRIASVWNIPVATNRATANFLFNSSLLEEEVIIEIPDYEAYLAERT
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: DHSO_BOVIN
Sequence: MAAAKPENLSLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTVVKVGSLVRHLQPGDRVAIEPGAPRETDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGPIGLVSLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILQISNESPQEIAKKVEGLLGSKPEVTIECTGVETSIQAGIYATHSGGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGLKVMIKCDPNDQNP
What is the function of this protein?
Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols.  Is mostly active with xylitol, D-sorbitol (D-glucitol) and L-iditol as substrates, leading to the C2-oxidized products D-xylulose, D-fructose and L-sorbose, respectively (PubMed:9143345).  Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism.  May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility (By similarity).  Cannot use NADP(+) as the electron acceptor.  Has no activity on ethanol, methanol, glycerol, galactitol and fructose 6-phosphate (PubMed:9143345).
What are the official names of this protein?
Sorbitol dehydrogenase, SDH, L-iditol 2-dehydrogenase, Polyol dehydrogenase, Xylitol dehydrogenase, XDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Peripheral membrane protein. Cell projection, cilium, flagellum. Note=Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
Protein: RLPA_ECOLI
Sequence: MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEISGADPRFEPLNATANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEAFDPTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSNNTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVSGPQGDILPVSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPAMVTPQAVSQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGPFASKAEASTLQQRLQTEAQLQSFITTAQ
What is the function of this protein?
Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
What are the official names of this protein?
Endolytic peptidoglycan transglycosylase RlpA, Rare lipoprotein A.
What is the protein family that this protein belongs to?
Belongs to the RlpA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Localizes at the septal ring. Is also associated with some other structures/complexes along the cell cylinder.
Protein: ADH1_GEOKN
Sequence: MSTAGKVIKCRAAVLWEKNKPFSIEEVEVVPPKAYEVRIKIVATGICRSDDHVVNGSIITPLPAILGHEAGGIVESIGEGVTTVKPGDKVIPLFVPQCGKCRACKHPESNLCTHGDLGRAQGTLMDGTSRFTCKGKPIHHFLGVTTFSEYTVVSEISVTKIDAASPLEKVCLIGCGFSTGYGSAVKVGKVARGSICSCVWSGRVGLSAIIGCKAAGAARIIAVDINKDKFAKAKELGATECVNPQDYDKPIYQVLQEMTDGGVDFSFEVIGRLDTMVSALMCCQESHGVSVIVGVPPNAQSLTMDPMVLLSGRSWKGAVFGGYKGKDDVPKLVADFMAKKFPLEPLITNVFPFAKINEGFDLLRAGKSIRTVLTF
What are the official names of this protein?
Alcohol dehydrogenase 1, Alcohol dehydrogenase A subunit.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP7_RHIRD
Sequence: MNFADTPLASLDLDWACEEFIKTYGASPQLETGEVIQTNNGLLYLYGKGSLSQRIHDTHLKFKEKEELSFTTIKPAEMKAQQSDLTYYVAIFQSNYFLCVSNPEKGFLRCHNRPFLYPIVAHGSMS
What are the official names of this protein?
Uncharacterized protein 7, Open reading frame 3.
Protein: TATR_NPVOP
Sequence: MPKNMETLQRSYMGPSTPNHNLFNNATELPDDLNFSTMDVPYDGSMPMNMSSDSLMNLLEDRSKKLACAVDTELARESTASEFVAGFSADSPQAQLAETGAETGAAGGSKRKASEVDSDSDSDDSSKGKKLVNKPKIRQRYKKATIQNRTSLTEERQYSTEICTVAAPDQIAKYFAQDFSAHLNEVKSECQMSANRFSDYISETGYYVFVVKKGDRKPFEVVFAKFVNNATNEYTNNYYMVDNRVFVVSLNNVKFMVSYKLVREQGIDIPPHVNLCNDAQAERTPLNCYFEPVKNAFQATLINHFHLDMFYAQTTFVTLMQAVGENKTNMLLNKLYQMYQDRSLFTLPIMLSRKEPVNENAPQNKNHAFSYVAQIMKYSKNLRFPQGDPTQQVMDRLEEIVTQKSSLTYKYSSVANLLFNRYGRRDNNADALKKVKKEDGNRLLVEQYMSYNENDDTSHNFIVLQFGGVNDERLTIAKRGKEFYWIAGEIKDISVDDLIKKYARNVHHVFRIINVNRRESTTWHNNLLKLLQLLLQNLIRLEDVQRYSDKSDTKFVYKKV
What is the function of this protein?
Regulatory transcriptional protein, which trans-activates gene expression from early baculovirus promoters.  Can also trans-activate its own promoter, suggesting that it is autoregulated during normal infection of insect cells.
What are the official names of this protein?
Trans-activating transcriptional regulatory protein, Immediate early protein 1, IE-1.
What is the protein family that this protein belongs to?
Belongs to the nucleopolyhedrovirus IE-1 protein family.
Protein: PYRG_BORGP
Sequence: MKKNLKILVITGGVISGIGKGVTSASIARLFRYDFRVTPIKCDGYLNTDPGTINPVEHGEVFVLDDGGEVDMDFGHYERFLNLNAKSSWNITMGKIYKKILENERKGKYLGRTVQLIPHVTDEIKSTIFQIASSENSEMLIIEIGGTVGDMENILFIETVRQIRHEIGSGNIAFIHLTYVPSPAGINEQKSKPTQQSVKTLNKAGIFPDLIIARSSQVLTDQIRKKVAMFCNVESNSIIDNIDVSTIYEIPISFYKQGVHEILSSKLNIKVDPKIEELSKLVGVIKSNFFVPKKIINIAICGKYAELDDSYASIRESLVHVGANLDLLIKSTLIDSNDLNESYLKEFDGIIVPGGFGGKGYEGKIIAIKYARENNIPFLGICLGLQLAVIEFARNVCGILDADTEENLLKDKPLKSPVIHLLPEQKGIKDKGATMRLGGYPVILKKNTIVFNLYGQDRIIERFRHRYEVNNDYIDLFEKNGLVVSGFSSDFKIAKLIEIPKNKFFVACQFHPELITRIENPAKLFLGLIKACI
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: MTNA_RHIME
Sequence: MKVGDRHYHTIWLNEDGRSVDIIDQRWLPHDLRVVTLKTVADVALAIRDMWVRGAPLIGVTAAYGVAIAMTKDPSDAHLDAVWDELHQTRPTAINLRWALDAMRDHLRPLPEAGRADAAYQRATEIAEEDIELNRAIGANGLKVIRQIAAKKKPGEPVRILTHCNAGWLATVDYGTATAPIYMAVEEGIPVHVYVDETRPRNQGAYLTAWEMSSHGVPHTLIVDNAGGHLMQHGDVDLVIVGTDRTTANGDVCNKIGTYLKALAARDNGVPFYVALPSPTIDWTVHDGVKEIPIEERPGDEVSFVQGRASDGSIASVRISPEGSPAANPAFDVTPARLITGLITERGIATPSPEGLKALFPERR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: SYTM_YEAST
Sequence: MKIQLVRWHCSRNALWNRAFYSTRKATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEKNYK
What are the official names of this protein?
Threonine--tRNA ligase, mitochondrial, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: COAA_SALPC
Sequence: MSIKEQSLMTPYLQFDRSQWAALRDSVPMTLTEDEIAQLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPEGDKTVAQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEELLQTWYINRFLKFREGAFTDPDSYFHNYAKLSKEEAVNTATSLWKEINWLNLKQNILPTRERASLIMTKSANHAVEQVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_XYLFA
Sequence: MVSQFDTQHLPSSNTALVAGVDEAGRGPLAGPVVVAAVVFDPSQPRINGLNDSKQLSPACRERLYAHIVERALAYKVVMIDSTQIDTLNIYQATMLGMRLAVEGVAHVAKSARIDGNRLPKNLPCPAEALVGGDARDRTIMAASILAKVTRDRHMVELHLQYPHYGFDKHKGYGTPAHLAALAEHGPCLEHRRSFAPVRKMLTLEAIHARQSTHQHNENSPTKAAFNMLLERDD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_PARXL
Sequence: MAQDPADGVYFGLMSGTSMDGVDGVAVRFAQGKPSVVLAEAFVGFAAGLRDALFALQQPGDNEIEREALAANALATRYAVCCHDLLHNSRVPAAEVRAIGVHGQTVRHRPEKGYTRQINNPALLAEMMHIDVIADFRSRDVAAGGQGAPLVPAFHATVFGAKNETRVVCNLGGISNITILNATGSVRGFDCGPANALLDEWAQRHLGKPFDENGHFAAGGQVDRTLLNALLDEPFFGQQPPKSTGRDLFNADWLDAKLPPFAALDHADVQATLVALTAVTVAREIERHASDAKAVYVCGGGARNPEILKALQQALEDSGVSGVPVMTTDALGVPPSQVEPLAFAWLAMRCVARLPGNLPAVTGASAERVLGAIYPR
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RL18_PELPB
Sequence: MSQIDKASRRQKIKDRSRGNVQGTSAKPRLCVYRSLSQIYAQLIDDVNGKTILAASTLSKDNSALKGSKSELCRIIGNQLGQKALAQGITCVVFDRNGFRYHGRVKALADGAREAGLIF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL2_SHESH
Sequence: MAIIKCKPTSAGRRHVVKVVNTDLHKGKPFAGLLAKKSKSGGRNNTGRITVRHIGGGHKQHYRIIDFKRIKDGIPAKVERLEYDPNRTANIALVLYADGERRYILAAKGMQAGDPIQSGIDAEIKVGNALPLRNIPIGSVVHAVEMKPGKGAQIARSAGTYVQVVARDGEYATLRLRSGEMRKVPVDCRATLGEVGNAEHMLRQLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPTGVPTKGYKTRSNKRTDKYIVRRRNKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CL12A_MOUSE
Sequence: MSEEIVYANLKIQDPDKKEETQKSDKCGGKVSADASHSQQKTVLILILLCLLLFIGMGVLGGIFYTTLATEMIKSNQLQRAKEELQENVFLQLKHNLNSSKKIKNLSAMLQSTATQLCRELYSKEPEHKCKPCPKGSEWYKDSCYSQLNQYGTWQESVMACSARNASLLKVKNKDVLEFIKYKKLRYFWLALLPRKDRTQYPLSEKMFLSEESERSTDDIDKKYCGYIDRVNVYYTYCTDENNIICEETASKVQLESVLNGLPEDSR
What is the function of this protein?
Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
What are the official names of this protein?
C-type lectin domain family 12 member A, C-type lectin-like molecule 1, CLL-1, Myeloid inhibitory C-type lectin-like receptor, MICL.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Ligand binding leads to internalization.
Protein: EFG_LISMO
Sequence: MAREFSLEKTRNIGIMAHIDAGKTTTTERILFYTGRIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWKGYRVNIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATTYGVPRVVFVNKMDKIGADFLYSVGTLHERLAANAHPIQLPIGAEDTFEGIIDLIEMNALYYEDDLGNDPHIKEIPADLKDLADEYRGKLVEAVAELDEELMMKYLEGEEITKEELKAGIRKGTLNVEFYPVVCGTAFKNKGVQPMLDAVLDYLPAPTDVPAINGVLPDGEEAARHADDSEPFSSLAFKVMTDPYVGRLTFFRVYSGTLNSGSYVQNSTKGKRERVGRILQMHANHREEISIVYAGDIAAAVGLKDTTTGDTLCDEKEQIILESMEFPEPVIQVAIEPKSKADQDKMGQALAKLAEEDPTFRAETDQETGQTLISGMGELHLDILVDRMRREFRVEANVGDPQVSYRETFRKSAQVEGKFVRQSGGRGQYGHVWIEFGPNEEGKGFEFENAIVGGVVPREYIPAVQAGLEGALDNGVLAGYPLIDIKAKLYDGSYHDVDSNEMAFKVAASMALRNAAKKCDPVILEPMMAVEVVIPEEYLGDIMGNITSRRGRVDGMEARGNAQVVRAFVPLANMFGYATHLRSGTQGRGVYTMQFDHYEEVPKSIAEEIIKANGGNNKED
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.