PharMolix/UniProtQA huggingface dataset:
Protein: RS2_XYLFA
Sequence: MPQVTMRQMLEAGVHFGHQTRYRHPKMSPNIFGARGKIHIINLEKTVPLFNDAMNFLSAVAQKRGSVLFVGTKRSARDAIKEEAERCGMPYMIQRWLGGTLTNFRTVKQSVARLKELELAETDGTFSKLVKHEVLRLRRESGKLQASLGGIKDMNRIPDAIFVIDIGHEDIAIKEAKKLGIPVVAVVDTNYDPSLVDYPIPGNDDAIRAVQLYARAAADAVLEGKAAMPNAAAVREEEFASAPDAGKKGRQAQPKKGKRASDAAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RSXB_SALSV
Sequence: MNTIWIAVGALTLLGLVFGAILGYASRRFAVEDDPVVEKIDAILPQSQCGQCGYPGCRPYAEAVGLQGEKINRCAPGGEAVMLKMAELLNVEPQPCDGEEQQAAPVRMLAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCIELRPVNETPDSWKWDLNTIPVRIIPVEQHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: ARCA_LATSK
Sequence: MTSPIHVNSEIGKLKTVLLKRPGKEVENITPDIMYRLLFDDIPYLPTIQKEHDQFAQTLRDNGVEVLYLENLAAEAIDAGDVKEAFLDKMLNESHIKSPQVQAALKDYLISMATLDMVEKIMAGVRTNEIDIKSKALIDVSADDDYPFYMDPMPNLYFTRDPAASMGDGLTINKMTFEARQRESMFMEVIMQHHPRFANQGAQVWRDRDHIDRMEGGDELILSDKVLAIGISQRTSAQSIEELAKVLFANHSGFEKILAIKIPHKHAMMHLDTVFTMIDYDKFTIHPGIQGAGGMVDTYILEPGNNDEIKITHQTDLEKVLRDALEVPELTLIPCGGGDAVVAPREQWNDGSNTLAIAPGVVVTYDRNYVSNENLRQYGIKVIEVPSSELSRGRGGPRCMSMPLVRRKT
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_SALPB
Sequence: MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHLGRLLQFKAWGLPVSDRVTLCDSPQAVLDFYHNVEKDRPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETRPIVFPTHCPVCGSDVERVEGEAVTRCTGGLICSAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAGKLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAAGLAAYFGTLEALQAATIDELQKVPDVGIVVATHVFNFFAEESNRDVIGQLLAEGVHWPAPVVINVQEIDSPFAGKTVVLTGSLSQMSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGITVIDEAEMIRLLGA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: LEXA_BACMK
Sequence: MEKLTKRQQDILDFIKLKVQEKGYPPSVREIGQAVGLASSSTVHGHLSRLEEKGYIRRDPTKPRAIEILGDNRTETQSVIQVPIIGKVTAGLPITAVESVEDHFPLPASIVAGADQVFMLRISGDSMIEAGIFDGDLVVVRQQQSAYNGEIVVALTEDNEATVKRFYKEKDHFRLQPENSSLEPIILKQVSVIGKVIGVYRDLH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SYYM_DICDI
Sequence: MIRNFTKGLLINNLNINKFGSTKIRPFCSTITKNDKNNVINILKKRGFIHQMTASDIEMIKMTSTNNNNNNDNNNNNNNNKVSLYAGFDPTADSLHIGNLLTLMVMLHFKRHGHNPIALMGGATALIGDPSGKSSDRVMLTEEFIEGNLKHIRENITAVLGEDTLVVNNIEWNKTMDVISFLREVGSYFRVGSMIKKDFIQNRLSDSNENGISFTEFCYSLFQANDFAHLFLKHGCSIQIGGSDQWGNITAGCDLIRKKLKGNAQGITIPLLTNSAGKKLGKSEGNSIWLSPHRTSPYKFYQYWIQVSDEDVERLLKLFTLIPLEEISILVQKHNENPHLRLGQKTIAEHVTRLIHGQKGVEEALNTTELLFGESNKLLTPNASTTKIGDFDIGYLLSRVNFIELERSKFVDNQTEPILNLFAQISDASKSKVKQLLQSKSIYLNNIPVASNSQFIQSSDLIANDFIYLKSGKKIYYLIKFI
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Probable tyrosine--tRNA ligase, mitochondrial, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYP_HELPS
Sequence: MLFSKLFAPTLKEPPKDAVLKSHKHLAQAGYIYQVGSGIYNFLPLAKKVLDKIENITHKRMQEHGAQNILMSFVVLASLWEKSGRLDKYGKELLVFKDRKDNDFVLSPTLEENITEIAANFIKSYKQLPVHLYQIHTKFRDEIRPRFGLVRAREFIMKDGYSFHEDAESLDKEFLNTQSAYKEILSDLGLDFRIVEADSGAIGGSKSREFVVLTECGEDTIVVCKNCDYAANIEIAKRSKRPEPLNVPKAQLAKFPTPNTTSAQSVAEFFKTEPYFVLKALVRKVIHKDKETLACFFVRGDDNLEEVKALNALNLLGANALELREASKEDLNNAGLIAGFIGPYGLKKHVSYIIFDEDLKEGDCLIVGANEKDFHAVGVDLKGFENLVYADIVQVKESDHCPDCQGELKYHKSLEVGHIFKLGQGYAKSLKASFLDKNGKERFFEMGCYGIGISRLLSAILEQKSDDLGCVWTKNTAPFDVVIVVSNWKDEAQKKLAFEVYERLRQKGVDALLDDRDARFGAKMRDFELIGERLALIVGKQTLESKEFECIKRANLEKQTLKDTELEEKILEMLKSE
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WOX14_ARATH
Sequence: MVKKKKEKEKSKEIEEMDREIQNGAYSGRVMTEEQMEILRKQIAVYAVICDQLVLLHNSLSSYHPLSSGVRPMVGGYFDPMGASSSSHRISTRHRWTPTSTQLQILESIYDEGSGTPNRRRIREIATELSEHGQITETNVYNWFQNRRARSKRKQPQTTTANGQADDVAVTTEERRSCGDSGGLESYEHILFPSPDLGIEHLLSIGKFMET
What is the function of this protein?
Transcription factor which may be involved in developmental processes.
What are the official names of this protein?
WUSCHEL-related homeobox 14, Homeodomain protein PALE-2, AtPALE2.
What is the protein family that this protein belongs to?
Belongs to the WUS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7A_SULIL
Sequence: MSKASYVKFEVPQDLADKVLEAVRKAKESGKIKKGTNETTKAVERGQAKLVVIAEDVQPEEIVAHLPLLCDEKKIPYVYVSSKKALGEACGLQVATASAAILEPGEAKDLVDEIVKRVNEIKGKTSS
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPH_OLTVI
Sequence: MNPLIAAASVVAAGLSVGLAAIGPGMGQGTAAGYAVEGIARQPEAEGKIRGALLLSFAFMESLTIYGLVVALALLFANPFAS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PVK3_PYCSU
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, PycSu-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXA_PSEE4
Sequence: MSSIDPRAIIDPSAKLAEGVEVGPWSIVGPDVEIGEGTVIGPHVVLKGPTRIGKHNRIYQFSSIGEDTPDMKYKGEPTRLVMGDHNVIREGVTIHRGTIQDRSETTLGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVGDWAILSGYTLVHQYCHIGAHAFSGMGTAIGKDVPAYVTVFGSPAEARSMNFEGLRRRGFSDEVLHALRRAYKIVYRQGLTVEQAMKELDELVAQFPEVELFRQSIANSARGITR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_ACISJ
Sequence: MKLLIDFFPIILFFAAFKVWGIYVATAVAIAATVVQIGYIRLKHGKVEPLQWLSLGVIVLFGGATLLAHSETFIKWKPTVLYWLMGGTLLVGQLVFRKNFIQSLMGAQIDLPAPVWRNLNWGWTGFFATMGVLNLWVAYNFDTDTWVNFKLFGGIGLMFAFVIAQALYLSRHVKDEGDAAPKDLQP
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPH_CERS1
Sequence: MTMPPLTLYLAAPRGFCAGVDRAIKIVEMALEKWGAPVYVRHEIVHNKFVVDRLRDMGAVFVEELDEAPTDRPVIFSAHGVPKAIPAEAERRNMVYVDATCPLVSKVHLEAERHHENGLQMIMIGHAGHPETVGTMGQLPEGEVLLVETVEDVAGLEVRDPERLAYITQTTLSIDDTAAIVAALRERFPAIAIPRKEDICYATTNRQGAVKAIAGRIDALLVIGAPNSSNSKRLVEVGRAAGCRVAQLVQRATDIDWEALQGATSVGVAAGASAPEVLVDEVIAAFRARFDTTVKAVETVKERVEFKVPRILREPAETP
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: IF5A_THEGJ
Sequence: MGDKTKVQVSKLKPGRYIIIDGEPCRIVNITVSSPGKHGSAKARIEAVGIFDGKVRSIVKPTSAEVDVPIIDKRVGQVIAITPDTVQIMDMETYELYDVPIETGVEDEVKDQLKEGITVEYWETLGRIQIKKVRGE
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_NEIG1
Sequence: MLQPTRLKYRKQQKGRNTGIATRGNKVSFGEFGLKAVGRGRLTARQIEAARRAMTRHIKRGGRIWIRVFPDKPITEKPIQVRMGGGKGNVEYYIAEIKPGKVLYEMDGVPEELAREAFELAAAKLPIPTTFVVRQVGQ
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SHOC2_MOUSE
Sequence: MSSSLGKEKDSKEKDPKVPSAKEREKESKASGGFGKESKEKEPKAKGKDAKDGKKESSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV
What is the function of this protein?
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation.  Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
What are the official names of this protein?
Leucine-rich repeat protein SHOC-2, Protein soc-2 homolog, Protein sur-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus upon growth factor stimulation.
Protein: LSPA_BRUA1
Sequence: MKRHAVWSSLFVVILAVLIDQGIKYLVESRMFYGQQIDLLPFLALFRTHNEGIAFSMLAWLHDGGLIAITLAVIAFVLYLWWTNAPERVFARYGFALVIGGAIGNLIDRVMHGYVVDYVLFHLPTWSFAVFNLADAFITIGAGLIILEEFLGWRRERISH
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SGCA_MESAU
Sequence: MAATLTWILLFVGLLAGLRDTKAQQTTLYPLVGRVFVHPLEHATFLRLPEHIAVPPTVRLTYQAHLQGHPDLPRWLRYTQRSPYSPGFLYGTPTPEDRGRQVIEVTAYNRDSFDTTRQRLLLLIEDPEGPRLPYQAEFLVRSHDVEEVLPSTPANRFLTALGGLWELGELQLLNITSALDRGGRVPLPIEGRKEGVYIKVGSATPFSTCLKMVASPDSYARCAQGQPPLLSCYDSLAPHFRVDWCNVSLVDKSVPEPLDEVPTPGDGILEHDPFFCPPTEATGRDFLADALVTLLVPLLVALLLTLLLAYIMCCRREGQLKRDMATSDIQMVHHCTIHGNTEELRQMAARREVPRPLSTLPMFNVRTGERLPPRVDSAQVPLILDQH
What is the function of this protein?
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
What are the official names of this protein?
Alpha-sarcoglycan, Alpha-SG, 50 kDa dystrophin-associated glycoprotein, 50DAG, Adhalin.
What is the protein family that this protein belongs to?
Belongs to the sarcoglycan alpha/epsilon family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Single- pass type I membrane protein. Cytoplasm, cytoskeleton.
Protein: RL18_DESAL
Sequence: MAKPSKKNRTHEKRKVRVRKKLFGTQDRPRLSVFRSAKHIYAQVIIDETGQTIAGASTLDKEAKDKGGFESKVEAAKFVGKLVAQRAKEKGVTKVVFDRNGFLYHGRVKAVSTGARDGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GPX1_ARATH
Sequence: MVSMTTSSSSYGTFSTVVNSSRPNSSATFLVPSLKFSTGISNFANLSNGFSLKSPINPGFLFKSRPFTVQARAAAEKTVHDFTVKDIDGKDVALNKFKGKVMLIVNVASRCGLTSSNYSELSHLYEKYKTQGFEILAFPCNQFGFQEPGSNSEIKQFACTRFKAEFPIFDKVDVNGPSTAPIYEFLKSNAGGFLGGLIKWNFEKFLIDKKGKVVERYPPTTSPFQIEKDIQKLLAA
What is the function of this protein?
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
What are the official names of this protein?
Phospholipid hydroperoxide glutathione peroxidase 1, chloroplastic, PHGPx.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: URDA_LIMF3
Sequence: MKAGTYKVKAKGHGSSFMPMEVTLSDDAIQRIQVDASGETSGIADEVFKRLPAKIVKGQTLNVDTVAGATISSRGVVGGVAEAITLAGGDADEWKQRAKPEIATQAAQVEEYQTDVVVVGAGGAGLAAATRSLQHDKQVVILEKFPQLGGNTTRAGGPMNAADPDWQRDFAALTGEKETLKRLANTPLEQIDPEYRADFERLREQIKEYIASGAQYLFDSNLLHEIQTYLGGKREDLAGHEIHGRYQLVKTLVDNALDSVKWLADLGVKFDQTDVTMPVGALWRRGHKPVEPMGYAFIHVLGDWVTEHGATILTETRAEHLLMENGRVVGVVAHKTDGTKVTVRAKSTFLTAGGFGANTPMVQKYNTYWEHIDDDIATTNSPAITGDGISLGQEAGAELTGMGFIQLMPVSDPVTGELFTGLQTPPGNFIMVNQEGKRFVNEFAERDTLAAAAIAQGGLFYLIADDKIKETAYNTTQESIDAQVEAGTLFKADTLAELAGKVGMDPATLEDTINKYNSYVDAGHDPEFGKSASHLKCEVAPFYATPRKPAIHHTMGGLAIDKHGHVLDKAERVIAGLYSAGENAGGLHAGNRLGGNSLADIFTFGRLAADTAAQENG
What is the function of this protein?
Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino-histidine).  Dihydrourocanate is present at higher concentrations in subjects with type 2 diabetes, and directly impairs glucose tolerance and insulin signaling at the level of insulin receptor substrate (IRS) through activation of p38 gamma (MAPK12)-p62-mTORC1.  Therefore, the UrdA enzyme from the gut bacteria L. fermentum strain NBRC 3956 may contribute to the pathogenesis of type 2 diabetes by producing the microbial metabolite dihydrourocanate.
What are the official names of this protein?
Urocanate reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Protein: GLMU_YERPN
Sequence: MSNSSMSVVILAAGKGTRMYSDLPKVLHPLAGKPMVQHVIDAAMKLGAQHVHLVYGHGGELLKKTLADPSLNWVLQAEQLGTGHAMQQAAPHFADDEDILMLYGDVPLISVDTLQRLLAAKPEGGIGLLTVKLDNPSGYGRIVRENGDVVGIVEHKDASDAQREINEINTGILVANGRDLKRWLSLLDNNNAQGEFYITDIIALAHADGKKIATVHPTRLSEVEGVNNRLQLSALERVFQTEQAEKLLLAGVMLLDPSRFDLRGELTHGRDITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGDDSEISPYTVLEDARLDANCTVGPFARLRPGAELAEGAHVGNFVEIKKARLGKGSKAGHLSYLGDAEIGAGVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVANGATIGAGTTVTRDVAENELVISRVKQVHIQGWKRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUBE_BPF41
Sequence: MKLDYNSREIFFGNEALIVADMSKGINGKPEFTNHKIVAGLVSVGSMEDQAETNSYPADDVPDHGVKKGATLLQGEMVFIQTDQALKEDILGQQRTENGLGWSPTGNWKTKCVQYLIKGRKRDKVTGEFVDGYRVVVYPNLTPTAEATKESETDSVDGVDPIQWTLAVQATESDIYLNGGKKVPAIEYEIWGEQAKDFVKKMESGLFIMQPDTVLAGAITLVAPVIPNVTTATKGNNDGTIVVPDTLKDSKGGTVKVTSVIKDAHGKVATNGQLAPGVYIVTFSADGYEDVTAGVSVTDHS
What is the function of this protein?
Forms the cylindrical rigid tail tube.
What are the official names of this protein?
Tail tube protein, TTP, Major tail protein, MTP.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus tail tube protein family.
What are the subcellular locations of this protein?
Virion.
Protein: TAL_BURMA
Sequence: MTTALDQLKQYTTVVADTGDFQQLAQYKPQDATTNPSLILKAVQKDAYRPILEKTVRDHAGESVGFIIDRLLIAFGTEILKLIPGRVSTEVDARLSFDTQRSIDKGREIIKLYEAAGVGRERVLIKLASTWEGIRAAEVLQREGIRCNMTLLFSLVQAAACAEAGAQLISPFVGRIYDWYRKQKGADWDEAQDGGANDPGVQSVRRIYTYYKHFGYRTEVMGASFRTTSQITELAGCDLLTISPELLQKLHDSTEAVARKLSPDEARDARLERVAIDESSFRFQLNDDAMATEKLAEGIRLFSADAVKLEKMIEALR
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THCC_RHOER
Sequence: MPTVTYVHPDGTKHEVEVPTGKRVMQAAIGAGIDGIVAECGGQAMCATCHVYVESPWADKFPSISEEEDEMLDDTVSPRTEASRLSCQLVVSDDVDGLIVRLPEEQV
What is the function of this protein?
Ferredoxin-type protein which transfers electrons from rhodocoxin reductase to cytochrome CYP116 (ThcB), which is involved in the degradation of thiocarbamate herbicides.
What are the official names of this protein?
Rhodocoxin.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
Protein: ATPE_FRATH
Sequence: MTKKYLKVDVVSPLGSVFKGEADMVSLRGSAGEMGIVYGHTELLSTLPAGVVNVRKGQHTDVLYVSGGIVEVTPTRVTIMVDDMERAENLNQAEAEKARARAKEVLKNPDASKLDIEAANKRLKEADARLKALNSSNGLYYSKDD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL6_METI4
Sequence: MSRIGKLPIKLPPGIKVSIEGNNVTLEGKKGKLFHRLPEFLKVHQQDGSLILENTADSRQSKAMYGLHRSLLNNAVMGVHEGFQKKLEINGIGFRAAVEGKKLVMNLGFSHPVVYEIPEGISVKVQDNTKLTIEGIDKCLVGAVAADIRGFYVPEPYKGKGIRYAGEVIRRKAGKTAQK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HOX11_ORYSJ
Sequence: MELGLSLGEAMADAGRELVLGLGMGRREEAAEAGRRDHEVRRELEFGSMSSRCGGSSPEPTVRLTLLPMVPGLGLPWPPPPPPSSESRHLEASTRGFDVNRPPSSGGGGGGGGAEEEQDDVAGAALSSSPNNSAGSFPMDDFSGHGLGGNDAAPGGGGGDRSCSRASDEDDGGSARKKLRLSKEQSAFLEESFKEHSTLNPKQKLALAKQLNLRPRQVEVWFQNRRARTKLKQTEVDCEYLKRCCETLTEENRRLQKELAELRALKTVHPFYMHLPATTLSMCPSCERVASNSAPATASSAATSSTAAPPAAPSSGGIAATSSSAAAAAAPDHRPSSFAALFSSPRGFPLSVAPQAQPPTSS
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX11, HD-ZIP protein HOX11, Homeodomain transcription factor HOX11, OsHox11.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMH_ACIBT
Sequence: MKIRILTIGQKMPAWVLTGFEDYFKRIQPFVQTQVIELPMAKRGKNDSEADILKYCQIEGESILNALKPNETLIALEVGGRELSTEKLADTMKQWMLEGNDVALAIGGPDGLSDQVRKAAAWHWSLSKLTMPHPLVRILLIEQLYRAMSINHNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.