Protein: CAZM_CHAGB
Sequence: MISVADLDYASRKSSIFLFAPHVGTFTKQSMDKLVRPLAASAHRDWILDTVAGLPTYWDALAVKIPNIGNAIPGRRQLTDLDTWFRHGAGDVTQDDATLPSIVVGPLVVLIQLTQYWRYLELTRPDHLEDSADLQADVVTRQTQPGAKVETLGFCAGLLAAVAVASAGNRQEFQKYGAVAVRLAMMAGALIDGQEARDKATRDGGSVSYAIAWRGQKPGEEAARIVKDLNPNAYFAVLYDEARATVTTTRRTAPSLVNRLRAADVTVAEIGIKGRIHSPDSERKNNTDLLVDLCKSFEDLQYADAASLALPTYNNEAEGRPVSRDRGNMTEMVIRAILVNQCNWYGTFKGATEGREPFVVTLGLERSVPPTLMRSLGPHQVHYEDLADNGIPPAPQSPPRAVIETQPQPQQQQDTTPPKILENDKDAIAVVGMSIKTAGADDLDEFVEMLKTGRSQHEPVTRERLMHDMLFRAAADSDPNHKYYGCFIRDSDAFDHRFFKRSPRESAAMDPQSRLAMQAAYQAVEQSGYFTETTAAPEGRDKKHVGVYLGVCGMDYDHNSTCHEPSAFTATGALRSFITGRVSHYFGWTGPSMTFDTACSSSAVAIHTACRNLLSGECTAALAGGANTITSMLWFQNLSAGSFVSPTGQCKPFDDAADGYCRAEGMAFVFLKKLSDAVRDGNPVLATIPSTAVYQNQNSTPLFVPNSPSLSMLFSDVMRQAGVAPRDISLVEAHGTGTPVGDPAEYESIRTALGGPRVGRTKPLPIGSVKGHIGHTEGASGAIALIKVIMMMRGGFIPPQASFTKMSHNIAVRPDDMMEVVTQLRPWADPHKIALLNNYGACGSNASLIVAQPPPALRAPTRGAHQHPEGRRYPFWIAGLDARAISAYAAKLIRYLPSSPQDIPTLADISFSMNRQSNRGLAQGFVFSSRSVAELQEKLAQAAGAAGKEAAALVGIEPVRAERPVVLCFGGQVSLFVGLDRALFDSAAVLRRHLDECDAAVTALGLDSIYPGIFEREPVQDTVKLQTMLFAMQYASAKSWMDCGLQGKVAAVVGHSFGEITALCVAGVLSLEDTIKLVAARARLVRDSWGPDPGAMMAVEADEGLVRELLQEANRSSDGSAGIACYNGPRSFTLAGSTSAVDAVQATMSADAKFKAIRSKRLNVTNAFHSALVEKLVDSLGQVGKELTFHPPTIPVERATETPFDAASMDWTFVPRHMREPVFFNHAVQRLAKQHPQAIFLEAGSNSTITIMASRALAQSQTSPPDAHHFQAVSITTATGFDGLTDATVALWKQGLRVAFWAHHALQTLEYAQLLLPPYQFDTSPSSRHWLEMKSPQKVIDKAVKALVAAGTPHQLPQNQTIDPKTLPLWTFVGYQDAPTNKTARFRINTESAQYNTYVLSHVIAQTAPICPGTLECDMMIEALFSLHADAQENGLQPEIRDLVNHTPICVDPSRTVYLELTALYKKRTQWSAHFLSVANGGGDAHNPQTHAEARLRLRAAGDADYLREFAQFERLVSHGRCRELLGLGLDVEGVEVLQGRGVYRAFDPVVEYGEVYRGVRYLVGRGNECAGHVQLPARHRGDTWLDVALSDSFSQVGGLWVNLMTDVPPGDMYIATGCEVTMRAPRATARGEGDVWHVYGRHARQSDKAYTTDLFVFDAATGSLVEVMLGLQYGRVAKASMSRMLARMTTDETVVRTKASLPQLPATNSSPPATAPAPAMAVVEASRNSKKRSKKTEKKEAKPKKTQKDSGWRDITEEVRNLVAHVSGIEASEIGLDSEMADFGIDSLMGMELGREVELTFKCKLDQAEQMEATSLRKFVAVVAKALFGTDQPAEVEDEASEAEDEDDDDSSSTGEGGTWSEPSQEDGSKESSGLQTPDSSSYTPPPEKAQKAGPVPGNLKPLNAPTAPPAVSNLVLSPADVLAAFGEVKMATDSLMREYEIDKTERTLLAGSNRLCAALVVEALDELGCPIGTAAAGQPLERVPFLPQHGRLMQCVYEFLERDARLIDIDVASGQLTRTHVAAPRKTSQAILEDLLTSQPEFAVANRLAYHAGKQLAGVLSGKTDGIRVLFGSPEGREVTAAMYCEHPFNRMSYRQMSDVVEGLAERIQSRGGTGETFKVLEMGAGTGGTTLVMAPLLASLEARGIMRVEYTFTDLSPSLVANARRRFGKMYPFMRFAVHDIEKSPAEELRGQHLVLASNAIHATHNLVVSASNVRQALRPDGFVMILEMTEVVPFIDLVFGLLEGWWLFDDGRNHAVVPAEHWERELHTAGFGHVDWTDGNLPENAVQKVIFAMASEPQGPRLPKAAPEQTMELDRGDVAARTAEAERLVTKYSNAWATPRLQALAARRETNQGQPKRNKANLGAVVLVTGATGSLGSHLVQKLAENPEVAQVVCLNRRSSSGLSAVKKQQEAFASRGITLSPGARAKLRVLDADTSQAQLALPPHEYTWLLQHGTHIVHNAWPMSGTRPISAFEPQLQGMRNLLDLAREMATRDAVHPFRVGFQFVSSIGVVGYAGEPRILEDRVPLSAVLPSGYGEGKWVCERLLDDTLHKYPSLFRPMVVRPGQISGSSNSGFWNPVEHFAFLVKSAQTLRAWPDFDGVLQWIPVDHCASVMADLLKMGVADAPDAYPVYHIDNPVGQQWKAMSPVLAAALDIPPHAIIPFSSWIKRVRRSPLLAETENPAARLVDFLDSHFERMSCGGLILDTTKAKEHSQTMAKEGPVDPDLARLYVAAWKKMEFLRS
What is the function of this protein?
Polyketide synthase; part of the Caz gene cluster that mediates the biosynthesis of the azaphilones chaetoviridin A and chaetomugilin A (PubMed:26172141, PubMed:23072467).  The substrate (S,E)-4-methyl-hex-2-enoyltriketide is transferred from the CazF acyl carrier protein domain to the CazM N-terminal acylcarrier protein (ACP) transacylase domain, and from there to the phosphopantetheinyl group of the CazM ACP domain, where it serves as a starter for the biosynthesis of cazaldehyde A, the precursor of chaetoviridin A and chaetomugilin A.  During this process, CazM consumes malonyl-CoA, S-adenosyl-L-methionine and NADPH to catalyze four rounds of chain elongation, cyclization and ultimately NADPH-dependent product release (PubMed:26172141).
What are the official names of this protein?
Iterative polyketide synthase CazM.