PharMolix/UniProtQA huggingface dataset:
Protein: AZOR_BURMA
Sequence: MTTILQINSAARSQGAQSTLLADELTAKLQQGNPGATVKVRNLLADALPHLDDAVLGAFFTPADQRSAEQNAIVAKSDELVDELRSADVIVIGAPMYNFGVSSQLKAYFDWIARAGVTFRYTSEGPEGLIKGKKAYVVSARGGKHVGMPTDSQTPFLKTFLGFIGLTDVTFVYAEGLALGPDAATEALASAREAIAAV
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: HEMA_I72A4
Sequence: MKTIIALSYIFCLVLGQDFPGNDNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDGFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFINEGFTWTGVTQNGGSNACKRGPDSGFFSRLNWLYKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTDQEQTSLYVQASGRVTVSTKRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDILVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIGTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: K2C72_BOVIN
Sequence: MSRQLNLYPGGERLAFSGCSAIISSRVSSSTASFRASGIKGTATFGSRSLFNCGGGRRPALSSAAGRGGSALGSCAATGGGRRGGFVGTVFGSAGLGPACPSVCPPGGIPQVTVNKSLLSPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLGTKWELLQQLDLNNCKNNLEPILEGYTSNLRKQLEMLSGDRVRLDSELRSMRDVVEEYKKRYEVEINRRTAAENEFVMLKKDVDAAYMNKVELQAKVDSLTDEIKFLKCLYEGEIAQLQSHISDTSVILSMDNNRDLDLDSIIAQVRAQYEEIALKSKAEAEALYQTKIQELQATAGQHGDDLKLTKAEISDLNRMIQRIRSEIGNVKKQCSNLEMAIADAEQRGDCALKDARAKLDELDAALLQAKEELARMMREYQELMSTKLALDMEIATYRKLLEGEECRMSGEYPNSVSISVISNTSTGAGGTGFSMGFGALSSYSYKSSAVDVKTKGSCGGSELKDAPAKTSGSSCATKKASR
What is the function of this protein?
Has a role in hair formation.  Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (By similarity).
What are the official names of this protein?
Keratin, type II cytoskeletal 72, Cytokeratin-72, CK-72, Keratin-72, K72, Type II inner root sheath-specific keratin-K6irs2, Type-II keratin Kb35.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: HSP1_SMIYO
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHHNRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y1530_SINMW
Sequence: MNDDSNGRRRRPAAFPVGTEDATSRELEQTPRRAPGSFSDKIVMTPDADDPFIETTAAIEALNPPEARPPRRRLSFGKIAAGAFGILISLAVGLWVDRLVRDLFSRADWLGYGAVAVVAIGAAAFLIVVAREIFGMMQLTAVQALKADLAAAAVAGKAQAARAATARLVHLLAGNPRTAKGRARLADTEGEIIDAPHLVDLTERELLAPLDREARRIILGAAKRVSIVTAVSPRALVDLGYVLYESARMIRAMAELYGGRPGTLGLLRLMRDVVAHLAVTGSIAVGDSLVQQILGHGLASKLSARLGEGVINGLMTARIGIAAMDLCRPMPFRALKRPSIGDFLADLAPGAGRTESATGKA
What are the official names of this protein?
UPF0283 membrane protein Smed_1530.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TIMP2_MOUSE
Sequence: MGAAARSLRLALGLLLLASLVRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSITQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
What is the function of this protein?
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
What are the official names of this protein?
Metalloproteinase inhibitor 2, Tissue inhibitor of metalloproteinases 2, TIMP-2.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURG_BAUCH
Sequence: MIRKRLIIVAGGTGGHIFPGLAIANNMITQGWDVRWLGTKNRIEADLVPKHGITTYFLSIYGYGLHGKKQKILAIVSILQAVLQSYYIMRKWRPDIVLGMGGYISGPCGLAAWMCKIPLVIHEQNRVTGLTNYYLSKFAKKVLQAFPSVFPNANVVGNPIRKEILAVIEPSLRLCNRTGPIRILVIGGSQGSKIINQILPVVAAQLAGKYVFWHQVGKGALKEVQQVYTSMLKNQLNYKLVEFIDDIAIAYAWADVVICRSGALTISEIAAVGLPAIFVPFMHKDRHQYWNALPLEQLGAAKILEQPNFTAEKVSQILMSWDRSKLFTMAQRARTIAMVDSTERVTSELIELANNTKH
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y359_BURTA
Sequence: MQMIYNSPNYCVVEFPPQDGHHAMNSGGYEIVDKNAQREIFIDGELAARFREHVKQLIQAEPSLDEVDEFLGQFDSLMTQPVVLH
What are the official names of this protein?
Protein BTH_I0359.
Protein: AXLP1_CAEBR
Sequence: MTMRSKTFSDRILNDSEFFKWCQKEESRNADSITLYKSILEFESKFKSGSPSLSLLKLARHIHRKYVSLNTGTCNVIEDSTRTEMSKRVHEVLDGKSPYIELFDPLKQPLFQHLRSMHTEYSTTTADVSNTWEDTSSTDSSDKGATIWFNDDAIDRSSRHEISQNTVTHESEDDRFAFFNAVCTRLNSLQETKNSSETEEEKKKERSADPYGSDGFAPPPQSTQTHTLRNLPKRFESLYKKKRQQNTTTTDSSGFGSNASDFWSFERYGKSNHGTLERPNRLFPGSNNGFSTLQPKKRSGEIQKLTVELRYENDVPMVAKISANQSVTLRYFRHLFGLHYSDNCRFFFKSTCEDGSAHYQWTLLFQDDDILPVFQNRITAICRMCPPPPEDHHLI
What is the function of this protein?
Works in parallel with pry-1 in negatively regulating bar-1 signaling in vulval precursor cells and Q neuroblasts.  Shown to have a role in excretory cell development (By similarity).
What are the official names of this protein?
Axin-like protein 1.
Protein: TX31D_SCOMU
Sequence: MKLSMAILLVMALIIFTLDKNYSSPKDLPSCEKGIHRKVTCKQCNKRSDNDDDYTKCCKSFDAFITCGFLLSKES
What is the function of this protein?
Inhibits voltage-gated potassium channels.
What are the official names of this protein?
Kappa-scoloptoxin(03)-Ssm1d, Kappa-SLPTX(03)-Ssm1d, Kappa-scoloptoxin-Ssm1d, Kappa-SLPTX-Ssm1d.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-03 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXD_SHIDS
Sequence: MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVNPKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAPSAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTIYHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRGALDDTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGHMEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLERKVNQQD
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, UDP-3-O-(3-OHC14)-GlcN N-acyltransferase, UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RL28_MICAN
Sequence: MSRVCTMTGKKANNAYAVSHSHRRTKKLQEANLQWKRVWWSEGNRWVKLRISTKAIKTIEKKGLAVFAREVGLNLNLY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ARFP1_MOUSE
Sequence: MAQESPKNSAAEIPVTSNGEVDDAHEHGYNRDLKHSLPSGLGLSETQITSHGFDSTKEGVTEAGAPQGSSAPPLPCVLSPSRVAASKLTQQAGDLTVPAGGQRTHTKGGPVILADEIKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQKQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYENARVEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQIHKEKYDKMRSDVSVKLKFLEENKVKVLRNQLVLFHSAVAAYFAGNQKQLELTLKQFHVRLKTPGVDAPSWLEEQ
What is the function of this protein?
Plays a role in controlling biogenesis of secretory granules at the trans-Golgi network.  Mechanisitically, binds ARF-GTP at the neck of a growing secretory granule precursor and forms a protective scaffold.  Once the granule precursor has been completely loaded, active PRKD1 phosphorylates ARFIP1 and releases it from ARFs.  In turn, ARFs induce fission.  Through this mechanism, ensures proper secretory granule formation at the Golgi of pancreatic beta cells.
What are the official names of this protein?
Arfaptin-1, ADP-ribosylation factor-interacting protein 1.
What are the subcellular locations of this protein?
Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
Protein: RL9_SHIB3
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ATG16_VANPO
Sequence: MDSLFVERLAQRDEVEGRFCELFKEVQIMVGPQLEDESMERKLIVALKSDLVEKDLRIGELEEILQLRNKDYERLNDELISLNIENNILRDKLQNMTEENSKLVKRWLNKVQQEADAMNENLH
What is the function of this protein?
Stabilizes the ATG5-ATG12 conjugate which is necessary for autophagy.  The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS).  Recruits also ATG3 to the PAS.  Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity).
What are the official names of this protein?
Autophagy-related protein 16.
What is the protein family that this protein belongs to?
Belongs to the ATG16 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: SEC16_PICGU
Sequence: MESDAGAQQPPEASENSNMYGGYQTETESDPLVYKSDNNHNPGSTNLDGPNSIVAQTEPNAVSERRTSVLQQADDVLPRHSSIDDAIASVARQSAGFSEDFLRRDSRVSASHSSHNEAGHHADSEQLETRLPVPENVQEHNNVSNTENHESTGAPADDSFFSELASRPETSEQFFSTHAQEEITPLVDPLQEVDERRESFPWEESKEGADFFSSLGNSEHNQTPASGTEEHEQSHVSTSFNEEETAITHGNEESIPWPSYDENSHEAHAQHTSEGAQETDSVAPSAHTVHESDSTPTPKPDSTNELDELFAGDDDDFLQEIVKDQEPVTSNGNQDTKTPSSQEPEPAEESQVKKKDSFAFLELDDDLLLDDDLLPDEEDEGEINSNATVVQPQTTTTSRYSRPSQPTSTSSSFSKPVAAQEFNKKLEEAKKKHDAYDFPSNLLHSSIKPAPRTNNKYAAPSGSAGSPNSASASAPPPSSTTSLPLHPQAAPGVAQENRPPLQSHSSAPNQAPSKSPAKKSFFEELPIPTPRAAVRPARSGPSKPSPVTAKPAVGQAQKKPTQPPVNPYAMQNLKTPSAASSPASAVPQVTLPNAPVGPVPPVAPIGGVVAPGPFSDMASVAPLPQSAPQNSLSATPNTTSQPRKLSNAGSSPYVPKVGPYGPSGHTRHHSRASSLVGAKGKEVNPYAPALSPVNASGGQMSPQNQASSLSAVAPPTAHSSATASRLRRISNPRSIYGNAVAQQLKPVDPNIRFQKQFPIFNWGLNNNVSMIPKNMQRNINIKQLTGGAFTEILKSFPGPLSKKSKAKDVEKWLKTKVTHLDSSTPNVATNEAKLSDEVGEILAALVASNGDVRSQEFISTACSVLNPHHYSQVEAMATPQGSNHSATAYKLDNSGSNQLLTYCQAGQTDRALELCVAAGDWALALIISHSMGPQAFGKTASDFARTSYPFQKSQSKLNHLMPIILKVFSGNVKSIIEDFQNVATELEWVLLHWRDVVTSIAANAIQNGKVNEFLNEFGQLLASHGNFIGRDVCFILTGAPLSPSFSVVGGDSQMGLFYTEIYEYALSQRSAATANTLLPTLSVKLHHAQLLADYGLNVDSQRYCDQIGASLKTTKQQVPPAIIHEFQRLLVRVSDTGANDQSWYGGIGKINKMWGQLDKLISGDENTEKKGETGLFSKFSPSVSRNASTTDIHALDRPEFHSMVSSMSAPITPGEQYGRTPSSVAPVTSLSGVSSSQTSNPLTSVPRYAPPAKNSRPQQSPQQPTRSHDMAPHSGSRYAPSNASSSNLGNPEEAIQSRKPPSKYSRPAQVGAAFSYNNPVAEASSSSIGSYGSHAVPNPPPATQGHTKQPSFNSIVSNDYSVIRDHNRSPSVQSDISLDYPVDFRERIAESKQESEENADIKQLNEIPTNGNGNENTQAQSSKDQSSPLPYANQSGTTMDSTEVASQQSQQPPPPPPKLTQTPTQSPSRGPPPAVSRSPSQPPKANPYAPGARTNKPRGRNRYGPPSALGSNAPSVPEVNGNRASEEPKNVNPKVHEEKTSNIDDSFTSSYQEDTQMSSPSLMLNHNQGAINQTERPNSKFGLGDEFPIPGSPEVTTRANSVYGGHGGFFSSRLSQSQQSTMYQQYEVTDDTVQDYVPVVEEEDEEEDAPKSQSSQPAQNGSKSAANAKGQTGLFSIFGMRKNDGKPKPIRAKMGEPMKLVYDEEMKAWIDPSIPRDQQLKKAAPPPPPKMKTSAKPSNVPSVGEAPSQQHTPQTGPVLPPGNSSGPTPKPIGSGPKPPAPRAGTKPQLANANLDDLLSLSSQPGAAGRKPKRGARRGYVNVMEQ
What is the function of this protein?
Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules.  Also involved in autophagy (By similarity).
What are the official names of this protein?
COPII coat assembly protein SEC16, Protein transport protein SEC16.
What is the protein family that this protein belongs to?
Belongs to the SEC16 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RLMN_SHESM
Sequence: MSEKKINLLDLDRKAMRALFADLGEKPFRADQLMKWIYHFGVSDFEEMTNINKVLRQKLAARCEIVAPEISSYQKSADGTIKFAIHVGEGQEVETVYIPEDDRATLCVSSQVGCALECTFCSTAQQGFNRNLTVSEIVGQIWRVSHFLGFAKDTGERPITNVVMMGMGEPLLNLANVIPAMDIMLDDFGFSLSKRRVTLSTSGVVPALDKLGDALDVALAVSIHAPNDELRDILVPVNKKYPLQEFLAGIRRYIAKSNANRGRVTVEYVMLDHINDSTEQAHELAQLMKDTPCKVNLIPFNPYPGSPYGRSSNSRIDRFSKVLMEYGLTVIVRKTRGDDIDAACGQLAGDIRDRTKRLAKKRMQENQISVTMN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_LEPIN
Sequence: MKASKYILPTEKENPADAVVASHRLMIRAGLVRKSSAGLYFYLPLGLKVLKKIEQIVREEMNSTGALEFDLPILTPSDFWEQSGRWSAMGKEMFRIQDRHDLSYALGPTHEESFSFLLKPLLKSYKDLPVNVYQIQTKFRDEIRPRFGVIRSREFIMKDAYSFHIDDSSLDDTYQAMRVAYRKIFDRCGLKTIPVQADSGSMGGSASEEFMVVSPIGEETLLLCNSCGYSSNSEKTPLILKKENSSAKFSEKKEISTPGKKTISEVSTLLGVSESETIKAVALKSEKKKILVFLRGDLELNLHKLHSLLKIADSEPMTDLEIRELGLIPGFISPIAPNDKIKVLYDRSLQKDFPYVVGSSKEDFHTQGFILEKEISGLPEFADVALAREGDLCPNCSFPLKAEKGIEVGHIFKLGDKYTKAFGIQVLDQNGKSKTLTMGCYGIGVNRTMATVIEQCNDEKGIFWPISIAPFEVSLVSIVKGEDQYFKIEEFYNVLMNEGIEVFWDDRDLGPGFKLKDSELIGFPIRITIGKKFFESGEISIYNRKKDQEDSFVFSGFDDLVARVESMRQELFTELR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_PSEU2
Sequence: MMRSHYCGQLNESLEGQEITLCGWVHRRRDHGGVIFLDIRDREGMAQVVFDPDRADSFAAADRVRSEYVVKVVGKVRARPAGAVNANMASGAIEVLGYELEVLNESETPPFPLNEYSDVGEETRLRYRFIDLRRPEMAEKLRLRSRITTSIRRYLDDNGFLDVETPILTRATPEGARDYLVPSRTHPGSFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQIDIETSFLNEEDIIGLTEKMVRQLFKEVLDLEFGDFPHMTFEEAMRRYGSDKPDLRNPLELVDVADQLTGVEFKVFSGPANDPKGRVAALRVPGAASMARSQIDDYTKFVSIYGAKGLAYIKVNERAKGPEGLQSPIVKFIPEDNLNVILDRVGAVDGDIVFFGADKFKIVSEALGALRIKIGNDLKLHTCEWAPMWVVDFPMFEENDDGSFTALHHPFTAPKCTPEELEANPATALSRAYDMVLNGTELGGGSIRIHRKEMQQAVFRLLGIAEDEQQEKFGFLLDALKYGAPPHGGLAFGLDRLVMLMTGAQSIREVIAFPKTQSAADVMTQAPGVVDAKALRELHIRLREQPKAE
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP53_BPAPS
Sequence: MLTANTPLLARLAENHTQMLMAHNQLTEAHTMLISQLVVQFEHDPHEPTEANKPKPFAQDVKPQPVAPSVIVEPKVVIEPAPVVEAHTKADDKPAPVVAEKKGKVAKAETKPAKAVKPMVEDPKVAPEPEPVDIESLDLRHVVSLSVLFGDKAVKPDHTQVAKAKATFAAEKADGVTGQIDALYCALNGISNIKTLSKTSTFDLCLKMLANWDNLFGITERREFALSLLHELPTPTEVKPIDFNALRSEASARITQLVKGGYRNEALDILASFNAKKLGDVTDDNLARFIEKAQSVLSDDKSEGSDG
What are the official names of this protein?
Putative protein p53.
Protein: Y288_STRP3
Sequence: MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYINKNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG
What are the official names of this protein?
UPF0298 protein SpyM3_0288.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_ECOSE
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: Y6066_FRASN
Sequence: MPLNQDFVGRSYTSDVPFQVGREHIRQFARAIGDGNPLFRDVEAAKAAGHADLVAPPTFLVTAIPGDLGLPTNDPALGLDYSLVVHGDQRFTLHRPVVAGDELVVRSTLASIRSVGRNEVLVTSYEFTTTSGELVAEGTCSLVSRGTAPPR
What are the official names of this protein?
UPF0336 protein Franean1_6066.
What is the protein family that this protein belongs to?
Belongs to the UPF0336 family.
Protein: BLAB8_ELIME
Sequence: MKGLKGLLVLALGFTGLQVFGQQNPDIKIEKLKDNLYVYTTYNTFKGTKYAANAVYMVTDKGVVVIDSPWGEDKFKSFTDEIYKKHGKKVIMNIATHSHDDRAGGLEYFGKLGAKTYSTKMTDSILAKENKPRAKYTFDNNKSFKVGKTEFQVYYPGKGHTADNVVVWFPKDKVLVGGCIVKSGDSKDLGFIGEAYVNDWTQSIHNIQQKFPDVQYVVAGHDDWKDQTSIQHTLDLISEYQQKQKASN
What is the function of this protein?
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
What are the official names of this protein?
Metallo-beta-lactamase type 2, B2 metallo-beta-lactamase, Beta-lactamase type II, Carbapenem-hydrolyzing beta-lactamase BlaB-8, CHbetaL-8, Class B carbapenemase BlaB-8, Metallo-beta-lactamase type II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CLEB_CONCL
Sequence: YRRRQCPPWCSGEPCRKGTC
What are the official names of this protein?
Conotoxin Cl14b, Conotoxin Cl14.3.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUC_AZOSB
Sequence: MEAQTLYEKLWSSHVVHQEADGTALIYIDRHLVHEVTSPQAFEGLKLAGRKPWRISSIVATADHNIPTDHWEMGIQDPVSRQQVETLDANIREVGSLAYFPFKDQRQGIIHVIGPENGTTLPGMTVVCGDSHTSTHGAFACLAHGIGTSEVEHVMATQCLLQKKSKTMLIKVEGTLGRGVTAKDVVLAIIGRIGTAGGTGYAIEFGGSAIRSLSMEGRMTVCNMAIEAGARAGLVAVDETTIDYLKDKPFAPKGPQWDAAVAYWRTLKSDDGATFDTVVELDATSILPQVTWGTSPEMVTTVDGRVPDPAAIADPVKREGVERALKYMGLAPNTPISEIAVDQVFIGSCTNSRIEDLREAAAVVKGRSKAASVRRVLVVPGSGLVKHQAEAEGLDKVFIEAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVTGHFTDVRTLN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RL5_TROW8
Sequence: MTCYTPRLLTRYREEIVPVLMSRFDINNVHQVPSITKIVVNSGVGDAARDSKIIEGAVSDITLITGQKPRINRAKQSIAKFKLREGQAVGVTATLRGRRMWEFLDRLLTLALPRIRDFRGISDKQFDGHGNYTFGLSEQGIFHEIDQDKIDRVRGMDITVVTTSSSDDMARALLGELGFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GUAA_HELPY
Sequence: MILVLDFGSQYTQLIARRLRERGIYTEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPSGKIFDLNVPILGICYGMQYLVDFFGGVVVGANEQEFGKAVLEITQNSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENGKIFGLQFHPEVVQSEEGGKILENFALLVCGCEKTWGMQHFAQREIARLKEKIANAKVLCAVSGGVDSTVVATLLHRAIKDNLIAVFVDHGLLRKNEKERVQAMFKDLKIPLNTIDAKEVFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGTLYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGVSQDFLMRHPFPGPGLAVRILGEISESKIKRLQEADFIFIEELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVSNRITNEVSGINRVVYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: XYNA_HALH5
Sequence: MITLFRKPFVAGLAISLLVGGGIGNVAAAQGGPPKSGVFGENEKRNDQPFAWQVASLSERYQEQFDIGAAVEPYQLEGRQAQILKHHYNSLVAENAMKPESLQPREGEWNWEGADKIVEFARKHNMELRFHTLVWHSQVPEWFFIDEDGNRMVDETDPDKREANKQLLLERMENHIKTVVERYKDDVTSWDVVNEVIDDGGGLRESEWYQITGTDYIKVAFETARKYGGEEAKLYINDYNTEVPSKRDDLYNLVKDLLEQGVPIDGVGHQSHIQIGWPSIEDTRASFEKFTSLGLDNQVTELDMSLYGWPPTGAYTSYDDIPAELLQAQADRYDQLFELYEELAADISSVTFWGIADNHTWLDGRAREYNNGVGIDAPFVFDHNYRVKPAYWRIID
What are the official names of this protein?
Endo-1,4-beta-xylanase A, Xylanase A, 1,4-beta-D-xylan xylanohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.