PharMolix/UniProtQA huggingface dataset:
Protein: TYDP2_XENLA
Sequence: MEVEEAGAVQTGTGEAVVANERTKQCSAFASITGCDEAVAQCFLAENDWDMERAINSYFEPGVESTLQNKPAADLADPLKQEMHAVTSDACIDLTSDDLVATKSEAVTSNSSTVKQQEDESHFTFLTWNIDGLDESNVAERARAVCSCLALYTPDVVFLQEVIPPYCEYLKKRAVSYKIITGNEDEYFTAMMLKKSRVKLISQEIVPYPSTLMMRNLLVANVNISGNSICLMTSHLESTKDHSKERLKQLDTVLKKMMDAPPSATVIFGGDTNLRDQEVAKIGGLPNTILDVWEFLGKPEHCRYTWDTKLNNNLRACYTSRLRFDRILYRASMEGSQVIPQFLNLVGTEKLDCGRFPSDHWGLLCDFDIIL
What is the function of this protein?
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate.  Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (top2) active site tyrosine residue.  Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals.
What are the official names of this protein?
Tyrosyl-DNA phosphodiesterase 2, Tyr-DNA phosphodiesterase 2, 5'-tyrosyl-DNA phosphodiesterase, 5'-Tyr-DNA phosphodiesterase, TRAF and TNF receptor-associated protein homolog.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family. TTRAP/TDP2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.
Protein: HIS8_CORGL
Sequence: MTKITLSDLPLREELRGEHAYGAPQLNVDIRLNTNENPYPPSEALVADLVATVDKIATELNRYPERDAVELRDELAAYITKQTGVAVTRDNLWAANGSNEILQQLLQAFGGPGRTALGFQPSYSMHPILAKGTHTEFIAVSRGADFRIDMDVALEEIRAKQPDIVFVTTPNNPTGDVTSLDDVERIINVAPGIVIVDEAYAEFSPSPSATTLLEKYPTKLVVSRTMSKAFDFAGGRLGYFVANPAFIDAVMLVRLPYHLSALSQAAAIVALRHSADTLGTVEKLSVERVRVAARLEELGYAVVPSESNFVFFGDFSDQHAAWQAFLDRGVLIRDVGIAGHLRTTIGVPEENDAFLDAAAEIIKLNL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: FLOA_EXISA
Sequence: MTPELLTTLLITGGGLIALAVFFTFVPVGLWISSFAAGVHVSIFTLIGMRLRRVIPSKIVNPLIKAVKAGIELNTNQLESHFLAGGNVDRVVNALIAAHRANIELSFERAAAIDLAGRNVLEAVQMSVNPKVIETPFIAGVAMDGIEVKAKARITVRANIDRLVGGAGEETIIARVGEGVVSTIGSQNNHKHVLENPDMISRTVLTKGLDSGTAFEILSIDIADIDIGKNIGAVLQTDQAEADKKIAQAKAEERRAMAIAREQEMKSSVEEMRAKVVGAEAEVPLAMAEALRNGKLGVMDYVNYLNVQADTEMRKAIGAPVDSESDNE
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: PYRB_LEGPA
Sequence: MKHFLEISQLSSEQIESLLQRALYFKHTKQYPSYSQSIIANLFYENSTRTRISFELAERHLAMSVVNLDLQTSSEIKGEAIEDTIRTLAAMGIQYFVIRHKQDGLQQNLANKLGDTVHIINAGDGTHAHPSQAILDMVTIIEQKKRLDKLKIAILGNIKHSRVANSFQCICSKLGVGDLVLISPEIWQPSQVHFGRVTDNLNEGLEGADVVICLRVQRERLLEDDHLDLDFYRNNFALTQKSLSYAKPDAMVMHPGPMNRGVEIDSEVADGNQSCILQQVTNGVYARMAILESLIAS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: SYS_ESCF3
Sequence: MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALAQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIR_BORBU
Sequence: MYYWDEILNLNFLVLKSFTILPVLVRIFMFLKFSPFFSTIKIGYFNFFFSLILSVIVVEKIKIIYPLDNMLSFALILLGEAILGLIQAFFVNIIFNVFHLVGFFFSNQIGLAYANIFDVFSEEDSMIISQIFAYLFLLLFLSSDFLLRFFVIGIHDSVLNIRVEHLVNMRNSGFVKLLLMSFGFLFEKALLISFPILSLLLLFYLVLGILSKSSPQINLLIISFSTSLFLGLLILYIGFPSLAISSKRVIELSLDSLASFLKLFSRVLK
What is the function of this protein?
Role in flagellar biosynthesis.
What are the official names of this protein?
Flagellar biosynthetic protein FliR.
What is the protein family that this protein belongs to?
Belongs to the FliR/MopE/SpaR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: VIME_CHICK
Sequence: MSFTSSKNSSYRRMFGGGSRPSSGTRYITSSTRYSLGSALRPSSARYVSASPGGVYRTKATSVRLRSSMPPMRMHDAVDFTLADAINTEFKANRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGKGTSRLGDLYEEEMRDVRRQVDQLTNDKARVEVERDNLADDIMRLREKLQEEMLQREEAESTLQSFRQDVDNASLAGLDLERPVESLQEEIVFLKKLHDEEIRELQAQLQEQHIQIDMDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQEANEYRRQIQSLTCEVDALKGSNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRINMPIPTFASLNLRETNIESQPIVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE
What is the function of this protein?
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.  Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
What are the official names of this protein?
Vimentin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Cell membrane.
Protein: RRP1L_DROME
Sequence: MVTRKKPVKRNAEAAEIQVEQEEDASQPKVAKELMVVAQEVKIIRALACNDVVERNRQIRILRKWFKARAGSSFPFNEDDFMRIWKGLYYTMWMSDKPLVQEELAEKLAQMVDSFGGNTACSLAYFSAFMRTMCQEYFGIDQWRMDKFLMLTRRMVRYLLRFLKQNNWNADLIAAFNSSMQLSVMSEQPKSRGMTMHYLDVFFEELAKAANGEITAAQVNMFLRPFVTYIATQRDAKLVAQCRTRVLYHLMYQSDLGRQYSEKYNAWKQMGFPTASIDDIEKLDSGFDEEDDEVNAEEEQPRATSLDPRAGNVDVHMPELPLNADCVLDELQTQLRTNDFNSKRRKGLRKLIQIFETYQRGEFPLGVRTMPKVEGQTLSEMVEQKVAALDKMEDEVFATGRKLKKLNKSKRKRLLQSINFEEVDEHNYDEVISKALPPELQKKVNYNAKVRSSINNAWVVEEVKEAEPKSKKAKKEEPPQQNKDDQTKVKKKSQLKPKNDQSKPKIEDQPTLKAEKEEPAKRKKLDHSKTKEEQSKPKTDEQPKPTPKVEGQSKAKPTPKTKAAGVDDDAPTNGWDAPLEDGEQDIFVPSRKLQVKQANSKLPQSTPKQPARAEFATPQTGSGKHVRIVTKSNCIYPKSDYYRQLKLSPQVPYDANRLPGKSALKPHWIPGPIHPSYKAKRLFNDTL
What is the function of this protein?
May be involved in the generation of 28S rRNA.
What are the official names of this protein?
Ribosomal RNA processing protein 1 homolog, NNP-1 homolog, RRP1-like protein.
What is the protein family that this protein belongs to?
Belongs to the RRP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH10_GEOSE
Sequence: MLKPLGDRVVIEVIETEEKTASGIVLPDTAKEKPQEGRVVAVGKGRVLDSGERVAPEVEVGDRIIFSKYAGTEVKYDGKEYLILRESDILAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUK_CLOTE
Sequence: MAHKLLIINPGSTSTKIGVFEDENLIFEETLRHSAEEIGKYSNVYEQFPFRKEVILNVLKEKGFDINTLDAIVGRGGLLKPVEGGTYEVNDAMLKDLRESVRGEHASNLGGIIGNEIAKSLNIPAFIVDPVVVDELQDIARISGMPEIERTSIFHALNQKAVARRYAKENNKSYEDVNIVVVHMGGGSSVGAHKNGKIIDVNNALDGEGPFSPERSGGVPIGDLVRLCYSGKYTLDEIIKKINGKGGAVAYLGTNDFREVEEKALAGDEKYKLILDAFIYQISKEIGKCSVVLEGNVDAIVLTGGIAYSKYVTKEIENKVKFIAPVVLYPGEDELLALTQGGLRVLNGEEKAKEYK
What is the function of this protein?
Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate.
What are the official names of this protein?
Butyrate kinase, BK.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FH1_ORYSJ
Sequence: MPSLRRFLELVVVGIVVCGVNGGSDGLEVAVARRQLHQPFFPDQSSSPPTPAPPGPAPPFFPALPVPPPPPATAGQEQPTYPALVLPNTGAGGAAATAAPDGGGGGGGGARKSKSSASKLVPAIVLPLLTVAVLGLSIAFFFTHRRGNAARGGGGGGGCVGGGDAKFLHPERASLFARDEFGGSGGAAAPPAAAMDYRYVGNAGIGRMDEKSSETTSSGDEASRSTGGSPELRPLPPLLARQCGPMGARSPGSGVGGFASPSSGDEEFYSPQGSSKMSTSHRTLAAAVEAAVAARDRSKSPSPGSIVSTPSYPSSPGATMSPAPASPPLFSSPGQSGRRSVKSRSDSVRTFGQPPAPPPPPPFAPTLPPPPPPRRKPPSPSPPSSPLIENTSALRSTTTTDTTIPRNPFVQPPPPPTHTHGPPPPPPPPPPPPVGYWESRVRKPGTGTSKETRSPALSPPPQAASFKSGLPTDAFPGRLADNADHAAAAAAGGGGDKSEETTPRPKLKPLHWDKVRASSDRVMVWDQLKSSSFQVNEEMIETLFICNPANSAPPKEPATRRPVLPTPKTDNKVLDPKKSQNIAILLRALNVSKEQVCDALCEGNTENFGAELLETLLKMAPTKEEEIKLREFKEETSPIKLGPAEKFLKAVLDIPFAFKRVDAMLYIANFESEVNYLKKSFETLETACDELRNSRLFLKLLEAVLKTGNRMNVGTNRGDAHAFKLDTLLKLVDVKGTDGKTTLLHFVVQEIIRTEGSHLSASNQSTPRTQANPLRDELECKKLGLQVVAGLGNELSNVKKAAAMDSDVLSSYVSKLAGGIEKITEVLRLNEEVKSREDAWRFHDSMQKFLKRADDDIIRVQAQESVALSLVKEITEYFHGDSAKEEAHPFRIFMVVRDFLSVLDQVCKEVGRINDRTIASSVRHFPVPVNPMMPQLFPRIHALRAGISDDESSATSASSP
What are the official names of this protein?
Formin-like protein 1, OsFH1.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-I subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACP_BACFR
Sequence: MSEIASRVKAIIVDKLGVEESEVTETASFTNDLGADSLDTVELIMEFEKEFGISIPDDQAEKIGTVQDAVAYIEEHAK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_THEVO
Sequence: MGRKDKYALIHYKLMDLSDYIEAGNKARRSIDLNHIEKIGRDIVNVFNSGGKLIVFGNGGSAADSQHFVAELSGHFSKERKALPAMALTVNTSALTAISNDYSYDVVFSRQLEAFAKPGDYVVGISTSGNSVNVVKGLERAKELGCKTLAMTGRSGGKIAKVAEEAIMIDSEVTSIIQEAHIAAIHMICSVIDSYY
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Probable phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_ECO81
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNTFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTDGIGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDRAVTITNRTVSRAEELTKLFAHTGSIQALGMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKLLQQELSA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: LIPA_PARDP
Sequence: MADMPPVLRHPEKAHRPDQPQPKKPDWIRVKAPTSQGYKDTRDILRNNRLSTVCEEAGCPNVGECWSQGHATMMIMGEICTRGCSFCNVMTGKPNALDVFEPGRVAHAVQKLGLKHVVITSVDRDDLDDGGAEHFAQTIRAIRHRSPASTIEVLTPDFLKSKPGALEAVVEARPDVFNHNLETVPGLYPTVRPGARYFHSLRLLQQVKELDPGMFTKSGIMVGLGEDRQGILQVMDDMRAADVDFITIGQYLQPTPKHHRVDRFVTPEEFKGYEKAAYGKGFLMVSATPLTRSSYHAGDDFAQLRAARLAKLGRA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_RHOPS
Sequence: MTPALKSTFVLAHRHLLGIEGLSAADITGLLDLSEEYVELNRQVDKKRASLRGRTQVNLFFEASTRTQSSFEIAGKRLGADVMNMSVSSSSMRKGETLMDTAVTLNAMHPDILVVRHHASGAVELLARKVDGSVINAGDGAHEHPTQALLDALTIRRNKGRLEGLVVAICGDVMHSRVARSNILLLNTMGARVRVVAPSTLLPRGIERMGVEVARDMREGLDGADIVMMLRLQRERMNGSFVPSSQEYFHYFGLDQKKLAYAKPDALVMHPGPMNRGVEIDSIVADGAQSVIREQVEMGVAVRMAVLEALARNLPNA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: IL15_BUBBU
Sequence: MRILKPYLRSTSIQCYLCLLLNSHFLTEAGIHVFILGCISAGLPKTEANWQYVINDLKTIEHLIQSIHMDATLYTEGDAHPNCKVTAMQCFLLELRVILHESKNAAIYEIIENLTMLANSNLSSIENKTELGCKECEELEEKSIKEFLKSFVHIVKMFINTS
What is the function of this protein?
Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems.  Stimulates the proliferation of natural killer cells, T-cells and B-cells and promotes the secretion of several cytokines.  In monocytes, induces the production of IL8 and monocyte chemotactic protein 1/CCL2, two chemokines that attract neutrophils and monocytes respectively to sites of infection.  Unlike most cytokines, which are secreted in soluble form, IL15 is expressed in association with its high affinity IL15RA on the surface of IL15-producing cells and delivers signals to target cells that express IL2RB and IL2RG receptor subunits.  Binding to its receptor triggers the phosphorylation of JAK1 and JAK3 and the recruitment and subsequent phosphorylation of signal transducer and activator of transcription-3/STAT3 and STAT5 (By similarity).  In mast cells, induces the rapid tyrosine phosphorylation of STAT6 and thereby controls mast cell survival and release of cytokines such as IL4 (By similarity).
What are the official names of this protein?
Interleukin-15, IL-15.
What is the protein family that this protein belongs to?
Belongs to the IL-15/IL-21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AIGLD_ARATH
Sequence: MSGTVTMHSVFVYGSLMADDVVRLLLNRIPQTASATLPDFHRFSIKGRVYPAIIPAKSDKVSGKVLFGITDDELNVLDEFEDVEYERENVQVLLTDSSDEKLQTKTYVWAKKDDPDLYGTWDFEEWKQLHMEGFLKMTKEFAEELNLPKSEI
What is the function of this protein?
Putative gamma-glutamylcyclotransferase.
What are the official names of this protein?
AIG2-like protein D, Avirulence-induced gene 2-like protein D, Putative gamma-glutamylcyclotransferase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: BH149_ARATH
Sequence: MVESLFPSIENTGESSRRKKPRISETAEAEIEARRVNEESLKRWKTNRVQQIYACKLVEALRRVRQRSSTTSNNETDKLVSGAAREIRDTADRVLAASARGTTRWSRAILASRVRAKLKKHRKAKKSTGNCKSRKGLTETNRIKLPAVERKLKILGRLVPGCRKVSVPNLLDEATDYIAALEMQVRAMEALAELLTAAAPRTTLTGT
What is the function of this protein?
Atypical bHLH transcription factor probably unable to bind DNA.  Negatively regulates brassinosteroid signaling.
What are the official names of this protein?
Transcription factor bHLH149, ATBS1 interacting factor 4, Basic helix-loop-helix protein 149, AtbHLH149, bHLH 149, Transcription factor EN 144, bHLH transcription factor bHLH149.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCF83_NEOYE
Sequence: MEGNMGFITITKPALKQIAILKNDHENDVHLRIGVRQGGCSGMSYSMNFEHVDKLKDTDERLRLDNFSVVCDPKSLLYLYGLSLDFSSELIGGGFQFSNPNASQTCGCGKSFSG
What are the official names of this protein?
Uncharacterized protein ycf83.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family. Ycf83 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GFAP_BOVIN
Sequence: MERRRVTSATRRSYVSSSEMVVGGRRLGPGTRLSLARMPPPLPARVDFSLAGALNSGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNLAQDLGTLRQKLQDETNQRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLAQQQVHVEMDVAKPDLTAALREIRTQYEAVASSNMHEAEEWYRSKFADLNDAAARNAELLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHAREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
What is the function of this protein?
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
What are the official names of this protein?
Glial fibrillary acidic protein, GFAP.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with intermediate filaments.
Protein: THIG_MYXXD
Sequence: MSIQDKPFTIAGVTFSSRLILGTGKYPSHDIMKRCHESSGTEMVTVAVRRLDLKATGEASLMNWIDRNRLRLLPNTALCYTADDAVRTCRLAEELGMSKWVKLEVLGDEKTLYPDVEETVKAARILVKEGFTVLPYTSDDPITARKLEDAGCAAVMPLAAPIGSGLGIRNPHNIRLILETVKVPVIVDAGVGTASDAAIAMELGVEAVLMNTAIAGAQDPVRMAVAMKKAVEAGRDAYLAGRIPRKAYGSASSPIDGLVHH
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_OLEA2
Sequence: MSRSDVFADAPPADWAQAVPLLREGAHLPLLRSVARLRRSKTVYPPEGQVFAALHCTPLHTVRVVIVGQDPYHGAGQAHGLAFSVPQGVKPPPSLRNVLKEAAAQKPEAPAAAGMQHNGVQTDLTPWAEQGVLLLNTALTVEAGRAGSHAALGWHAVTDDIIRTVSERCPAVVFMLWGNHARQKAALVDTGRHLLLESVHPSPFSAHKGFLGCGHFVTANSWLAARGLLPVLW
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_SODGM
Sequence: MDKFCVQGPTRLSGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDIDTTMKLLGQLGARVERNGSVHVDASDVDVYCAPYELVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLRGAHIVMDKVSVGATITIMSAATLATGTTIIENAAREPEIVDTANFLITLGAKISGAGTDKITIEGVERLGGGVYRVLPDRIETGTFLVAAAISRGRVVCHATRPDTLDAVLAKLREAGADIAVGDDWISLDMHGQRPKAVTVRTAPHPGFPTDMQAQFSLLNLVADGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICHGVETLSGAQVMATDLRASASLVLAGCIAEGVTVVDRIYHIDRGYDCIEEKLRRMGANIERIRGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB_METFK
Sequence: MTIKVLIIDDSALIRSLLTEIINQQPDLEVVGTAPDPLIAREMIKQKNPDVLTLDVEMPKMDGLDFLERLMRLRPMPVVMISSLTERGSEITMRAMELGAVDFVTKPKISIANGMHEYSEMIADKIRAASRARLIARKPLTPVAGGAGLPLVGNPLISSEKLIIIGASTGGTEAIKSFLMQMPSDCPGILITQHMPAGFTQSFANRLNALCKISVQEAKGGERVLPGHAYIAPGHSHLLLARSGANYVTQLDDGPPVSRHRPSVDVLFSSAANNAGKNAIGVILTGMGKDGAEGMLKMKQAGAYNFAQDEASCVVFGMPKEAIAMGGVDDVSSLNDMPGRVLQYLAANSGRALRV
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_CAMJJ
Sequence: MKKAYYGDFGGQFLPESAMFALNELEGAFLKFSKDKLFKKELNELLKTYVGRPTPLYFARNLSKKYQHEIYLKREDLNHTGAHKINNAIAQALLAKKMGKKKIIAETGAGQHGLATATAAALLGLECEIYMGATDVQRQALNVYKMELLGAKIHAVQSGLKTLKEATTAAIQAWVGDIKNIFYVVGSAVGPYPYPKMVMHFQSIIGKECKMQLQKLNKKVDYIIAAVGGGSNAAGIFYDFIKDENVKLIGIEAGGLGIDTPYHAATLNKGKTGIIHGMKTKVLQDDLGNILPVHSVSAGLDYPGIGPLHAFLFESKRAQYHAISDEECMQALKLLCKEEGIIAAIESSHALAFLEKLCPTLKKKSVIVVNLSGRGDKDMQMIRDYKKGVIYG
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: GCH3_METTH
Sequence: MIQMTLIQIDNYGPWTVTPTPRNEADLQIMQAELYADLQRQFAARQGLVFFTRFDNMLAVTNGMDLEDHRRIQKSIGNRYPITVSMGVGAAETPYDAQRNASRALQSHGGAQSEERKEVLAIDGLVDEGYVQIAHIDINGITETMTDIVPAYDTSFIVNRVQHFLMKKLIKEGALLFFIGGDNFMSPCNGLEPQGLLRIINEIDDEINVALKAGIGKAPTAEKAANLADLALEEIRGGFTYDLVHVMKE
What is the function of this protein?
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP.  Also has an independent pyrophosphate phosphohydrolase activity.
What are the official names of this protein?
GTP cyclohydrolase III.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GTP cyclohydrolase family.
Protein: SYL_CHLT3
Sequence: MKYDFTEIEKKWQAYWEQHQTFKATEEPNKPKYYVLDMFPYPSGSGLHVGHLEGYTASDITARYKRLKGFSVLHPMGWDAFGLPAEQYAIKTGTHPRLTTETNVANFKSTLQRMGFSYDWSREINTTDPGYVKWTQWIFLKLYEKGLAYVDDVPVNWCEELKVVLANEEVDEKVNDGYTVVRRPLRQWMLKITAYAERLLTDLDEVDWPESVKEMQRNWIGKSVGAELDFYLAGTDEKFRIFTTRPDTVFGATYMVLSPEHPLLDKITTDEHKSAVAAYREEAERKSDLERTGLQKEKTGVFTGSYALNPATGKEIPIWTSDFVLMGYGTGAIMSVPAHDERDWEFAKKFGIPIVEVIKSPHSVQEAVFAGKDSVCTNSENAEISINGLAYEEAFEKITDWFEKKGLGQRKVNYKLRDWLFSRQRYWGEPIPIKHYEDGAERAETELPLNLPEVSAYQPSGTGESPLANIAEWLYGEDEHGKFRRETNTMPQWAGSCWYYLRFIDPDNPNEAVSPEKEKYWMNVDLYIGGAEHAVLHLLYARFWHKVLYDVGVVSTKEPFRKLFNQGMILGEDNEKMSKSRGNVITADSVMSGYGADAVRLYEMFLGPLEQVKPWSTNGIEGISRFLGKVWRLVYPNEADGTVQVTDDAPSETVLRRMHKTIKKVGEDTETLKFNTAISEMMIYVNELQKEKCRSRTAIENLLLMLSPFAPHICEELWQALGHEESITFAKFPEYDATLAKDDVVTIAVQVNGKLRGTFDAAAGLSKDDMIAEAMKVESVIKFTEGKEIVKQIAVPNKLVNLVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3187_PHOPR
Sequence: MDYEFKKNTLDGSYHATFSMGHEIIGRWLIEEVGKDFEKMDTILSQIGALKNSTKEWRLLGDDLSLILQDHEAIIQANYLFSEEEEDFDEDMHFYDEESVSCCGFEDFELVLQAWQAFVTRF
What are the official names of this protein?
UPF0231 protein PBPRA3187.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.