PharMolix/UniProtQA huggingface dataset:
Protein: RL331_STAA3
Sequence: MFNVRVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNKYTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL4_BRASO
Sequence: MELKVTTLEGKEAGSVQLSDAIFGLEPRADIIQRCVQWQLNKRQAGTHKAKGRAEIWRTGKKMYKQKGTGGARHGSARVPQFRGGGRAFGPVVRSHATDLPKKVRALALKHALSAKAKDGDLVVLENATLEAAKTKALIGHFSGLGLTNALIIDGAELHNGFAAAARNIPNLDVLPIQGINVYDILRRQKLVLTKAAIDALEARFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y1488_METJA
Sequence: MRIGIVGAGLGGLLAGALLSKNHEVVVFEKLPFLGGRFTNLKYEGFQLTTGALHMIPHGNDGYLAQALRKAGANVKIINSKPDGTFLINGKEYLYKELFSLLGFKEKAKAFKLATKLKLGKVDKNISFGEFLEEIDLALKVGNAFTGWALSLTAYETPMSEIIEIAKNYHKFGGPGIPIGGCKAVTDELSRIIKKNNGKIIKEYEVKRIEIDEKAYIDDYEFDVVISNISPIETQKICNIKFLKSKPKPSKGIKISIATKEGIIKHGGVLFTPECERINGLNQVTNVDKSLAPEGWHLVMTHQTQLTNNVKKEIDLGLEDIENLFKGKDYKILHIQSYRDDWPVNHASNGTDIDNIVNDRFYLVGDGAKGRGGIEVEGIAMGVLKVVNYINSL
What are the official names of this protein?
Uncharacterized protein MJ1488.
Protein: VP35L_DANRE
Sequence: MASVQWHSRSRKYDSEWQASRLEVSAVEFSDYHPLKAITVTDSKSRRGGRKGSTSSSSSSSSSVAPDPLSSMLDGTDPLSLFAAASETPTLPHSVSAGELGRKRKEKEEEVGLDFEPWSSKRGEILSRFTTTEKLSINLFMGSDTSKASSPSSAVSEKVRTRLEELDDLEEGSQRELLNLSQQDYVNRIEELNQSLKEAWGSDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGGLVYDRIWSMCADPHPLPESFSADDVNDTAKETCLNWFFKIASIRELVPRLYVEAALLKCNRFLTKCGIQETLQRLTAMIRGIGDPLVAVYARAYLCRVGMEVAPHLKDSLNKNFFDLLASFRQIHGDSVQNQLVLQRVEIPVYLTLYSPAINWILQCVAYRAPEVLLTEMMDRCKKLGNNALLLNSVMWAFRAEFVATRATDFIGMIKDCDEAGFPKHLLFASLGRSLSCADPPESERLSILNEAWKVITKVRSPRDYINCAEIWVEFTCRHFTKREVNTVLADIIKHMTPDRAFEDAYPQLQSVIKKILTYFHDFSMLFSMEKFLPFLDMFQKDSVRVEVCKSIMEVFIKHQQEPTRDPVILNALLHICKTMHDSVNALTLDDEKRSLALLINGFIRMVSFGRDFEQQLSFCVEARATFCNLEPVIIHLIHTVNQLAMETGRVMKGNHSRKTAAFVRACAAYSFITIPSLTNIFSRLNLYLLSGQVALANQCLSQADAFLKAAVSILPEVPRSISIEGKQRSSESFLLDFINNFLSTLLVVPDHPEQGVLYLVRGLLNMVQDYTWEDNSDAKVRVYISALPLLAAMSQESYLYTIPKVDSNETLYGGDPKFIAEINKLCETLIGQVLDHLKSLGRDEEVRRQGSLAFSLFGCLLAHGDLRNNKLNQLAVNLWNLSHKHGICDTRTSVRTLEHIKHQAQQTDMSHFSDMTARLSLQSRA
What is the function of this protein?
Acts as component of the retriever complex.  The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrins.  The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes.  In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling.  May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery.
What are the official names of this protein?
VPS35 endosomal protein-sorting factor-like.
What is the protein family that this protein belongs to?
Belongs to the VPS35L family.
What are the subcellular locations of this protein?
Endosome.
Protein: RF1_PHOPR
Sequence: MKSSILVKLETLVERYEEIQHLLGDPGIIGDQNKFRALSKEYSQLEDITQCFQAYLGAKDDLEAAEEMAKDDDPEMREMAQEEVKESKANILRLEDELQVLLIPKDPNDDRNCFVEIRAGAGGDEAGIFAGDLFRMYSRYAERRGWRIEVINENRSEQGGYKEMIAKVSGDGAYGVLKFESGGHRVQRVPATESQGRVHTSACTVAVMPEVPEAEIPEINTGDLKIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKAMSVLAARITKAEEEKRHAEEASTRRNLLGSGDRSDRIRTYNYPQGRVSDHRITLTLYRLNEVMEGDMDSLIQPVIQEHQADELAAMAEQN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXZ_RECAM
Sequence: MFKNRKSIAILIAAVSITMIGFSYGSVPLYRIFCQVTGFGGTTQVADLESDILTLKDEQQENRIITVRFNGDVSDTMPWKFHPIQQEIKVMVGETALAFYSAENPTDSSIIGISTYNVNPQQAGIYFNKIQCFCFEEQRLKPHETIDMPVFFFIDPAILDDPKMSDIDSITLSYTFFNVEDL
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein ctaG.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Protein: ATPF_AKKM8
Sequence: MLNLIADQAWNPFAPFGVTSWEPFVANLIAFILMVVILRYLAFKPIQNVLEKRRQRIEEGEEMREESERQLASVKEQTHEMLVEAGEKGQEKIDAAKAAAARLLEEQEAEASRKAEEIIKKARQLAELEQQKEREALKEQFGQLVALAAAQVTGKMLTEEDQRRINREAIDSLDS
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ISC1_PHYSP
Sequence: MAALSSATKRLGRLIPHSSVLFVCDVQEVFRGLTFQLPTVIHGTNTMVSAAKLLNVPVVVTTQYGSRLGSTVSEISKNLEDAPDVKVFDKMKFSMLVPEVERHLTTNMPQRKSVLLCGIETHVCVLQTCLDLLDKGYDVHVVSDAVSSSTSYNRSMALERIRQSGAYITSVESAIFQLANDAGNPEFKSISKLIKEHLKVQNGFDTGARI
What is the function of this protein?
Secreted isochorismatase required for full virulence of P. sojae (PubMed:25156390).  Suppresses salicylate-mediated innate immunity of the host by disrupting the plant salicylate metabolism pathway via hydrolysis of its isochorismate precursor (PubMed:25156390).
What are the official names of this protein?
Secreted isochorismatase effector Isc1.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus. Note=Lacks a signal peptide and uses an unconventional secretion pathway for delivering effectors which plays an important role in host-pathogen interactions.
Protein: PE48A_LUCCU
Sequence: MIIKTLLASVAIMLIATVNAEYNVAKYCELVKIGTLMPSMISCQDYYICRLNNQPIPVKCGANTVFDKDTQGCVPEAQANCILSLDNPCENKDRTFAPSSKACNEWHYCLNGNIVANGSCQPGQIFDASKNSCIYGACNSDDDDSNSDFTPVLNICDIMQNGQFFGDFENCQNWQKCNNGRLQKGICLGNLVYDTKNGMCLQNDGTMCERTNGMVSEDGGAPDETLCTSSNDGPLPDKLTCSVYYICEQDTTSTPTTYKWIKTSCPNGQYFDVFGDGCLDRAKRRVYTGCNRCEYTTGSTTYWVNAVSNDCTKFSTCRNGRKITNEDGSCNSGYYFNEADQYCNMGDFTNYAETNGACQNYSCNGYDCTTKPSAT
What is the function of this protein?
May bind chitin or related oligosaccharide structures.
What are the official names of this protein?
Peritrophin-48.
Protein: MUTYH_RAT
Sequence: MKKLRASVRSHKKQPANHKRRGKCALSSSQAKPSGLDGLAKQKREELLKTPVSPYHLFSDIADVTAFRRNLLSWYDQEKRDLPWRKRVKEETNLDRRAYAVWVSEVMLQQTQVATVIDYYTRWMQKWPTLQDLASASLEEVNQLWSGLGYYSRGRRLQEGARKVVEELGGHVPRTAETLQQLLPGVGRYTAGAIASIAFDQVTGVVDGNVIRVLCRVRAIGADPTSSFVSHHLWDLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCNHCPVQSLCRAHQRVGQGRLSALPGSPDIEECALNTRQCQLCLPSTNPWDPNMGVVNFPRKASRRPPREEYSATCVVEQPGATGGPLILLVQRPNSGLLAGLWEFPSVTLEPSGQHQHKALLQELQHWSAPLPTTPLQHLGEVIHVFSHIKLTYQVYSLALEGQTPASTTLPGARWLTWEEFRNAAVSTAMKKVFRVYEEHRRGTCKGSKRPQVCTPSSRKKPSRGQQVLDRFFQRHIPTHKPNSTTQ
What is the function of this protein?
Involved in oxidative DNA damage repair.  Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone.  Possesses both adenine and 2-OH-A DNA glycosylase activities.
What are the official names of this protein?
Adenine DNA glycosylase, MutY homolog, rMYH.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: CALL_DROME
Sequence: MSELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEKVTDEEIDEMIREADFDGDGMINYEEFVWMISQK
What is the function of this protein?
May be involved in calcium-mediated signal transduction.
What are the official names of this protein?
Calmodulin-related protein 97A, Protein androcam.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: PSBL_CERDE
Sequence: MTQSNPNEQSVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y583_THET8
Sequence: MEGIRRAAQRAAEEFLQAFPMAPGSLFVLGGSTSEVLGERVGTRPSLEAAHAVLEGLLPPLLERGVHVAVQACEHLNRALVVERETARAFGLEEVAVFPHPKAGGALATAAFLRFRDPVMVESLKAQAHGGMDIGGVLIGMHLRPVAVPLRLSVRKIGEAVLLAAKTRPKLVGGARAVYTREEMLKKLEEFLPKPP
What are the official names of this protein?
UPF0340 protein TTHA0583, TT1679.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: PROAZ_OLEEU
Sequence: MSWQTYVDDHLMFDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLIEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-4, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYI_MYCTU
Sequence: MTDNAYPKLAGGAPDLPALELEVLDYWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVERQLGITDKSQIEAMGIAAFNDACRASVLRYTDEWQAYVTRQARWVDFDNDYKTLDLAYMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTVGFKVVGGQPDNGLDGAYLLVWTTTPWTLPSNLAVAVSPDITYVQVQAGDRRFVLAEARLAAYARELGEEPVVLGTYRGAELLGTRYLPPFAYFMDWPNAFQVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAVGIAPVTPVDSKGRFDVTVADYQGQHVFDANAQIVRDLKTQSGPAAVNGPVLIRHETYEHPYPHCWRCRNPLIYRSVSSWFVRVTDFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDELERDFGVRPANLHRPYIDELTRPNPDDPTGRSTMRRIPDVLDVWFDSGSMPYAQVHYPFENLDWFQGHYPGDFIVEYIGQTRGWFYTLHVLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDVTEVFDRDGSDAMRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPLWNTYSFLALYAPKVGTWRVDSVHVLDRYILAKLAVLRDDLSESMEVYDIPGACEHLRQFTEALTNWYVRRSRSRFWAEDADAIDTLHTVLEVTTRLAAPLLPLITEIIWRGLTRERSVHLTDWPAPDLLPSDADLVAAMDQVRDVCSAASSLRKAKKLRVRLPLPKLIVAVENPQLLRPFVDLIGDELNVKQVELTDAIDTYGRFELTVNARVAGPRLGKDVQAAIKAVKAGDGVINPDGTLLAGPAVLTPDEYNSRLVAADPESTAALPDGAGLVVLDGTVTAELEAEGWAKDRIRELQELRKSTGLDVSDRIRVVMSVPAEREDWARTHRDLIAGEILATDFEFADLADGVAIGDGVRVSIEKT
What is the function of this protein?
Confers high-level resistance to the antibiotic mupirocin (pseudomonic acid A), an Ile-analog that competitively inhibits activation by Ile-tRNA synthetase, thus inhibiting protein biosynthesis.
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSF2_MOUSE
Sequence: MWLQNLLFLGIVVYSLSAPTRSPITVTRPWKHVEAIKEALNLLDDMPVTLNEEVEVVSNEFSFKKLTCVQTRLKIFEQGLRGNFTKLKGALNMTASYYQTYCPPTPETDCETQVTTYADFIDSLKTFLTDIPFECKKPGQK
What is the function of this protein?
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
What are the official names of this protein?
Granulocyte-macrophage colony-stimulating factor, GM-CSF, Colony-stimulating factor, CSF.
What is the protein family that this protein belongs to?
Belongs to the GM-CSF family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF2_DESPS
Sequence: MSRIRIYELAKEAGMSGKAFADKLIKKGYQIKGHSSTVDDATADEIRRTFLGTKESGQDTGQATNEAAAAHRPTTVIGGKKVDEPVVPEKIVEEVQAVSVEVPKEVVAEEVKKSEPVKAEKSEPVIQEVAPVVEELVTNKEAPTAPLEREEESQLKAQKPTIEKEESAAVAKPEVVSAGSNEKKAGAPEIKRAEHTETVEKSKTAVDSKKVATPASTDKKVKPAQQPYRSGGVRVIGRVELPIQREEPSRPRRKPTRPPVNRSPRPSTPSPNRSAGGPPKPAAPATPAQDDSRNRKKKGRRDEKPAERDSRPKAKGKKGVKFTHFGTDYQNRGRRPRRGKRDAQTLPPSEMKASKKHVKVYDTITVGDLAGRMKVKASDVIGKLMGLGLMATINQSVDIDTATLIATEYGYEVDQGITDELGIQLLTEAEEGGIEVGRCPVVTVMGHVDHGKTSILDAIRKTDVADGEAGGITQHIGAYHVKAASGDVTFVDTPGHAAFTEMRSRGAQVTDIVILVVAADDGVMDQTREAIRHSQAANVPIIVAVNKIDKDNADVERVKRELAELDLSPEEWGGTTMYCETSAKQQIGIDELMESVQLAAEMLELKANPDRKVIGRVLEAQLDKGRGPVATILVQAGTLAKGDHFVVGQHSGKVRAMLDYRGRSLAEAGPSIPVEVQGLSGVPSAGDEFVVVTDEKMAKAVSHDRAMKAREAELGASTKISLDKLFEQMSEGEVRELRVVLRADVQGTLEAFAKAAADLSTKAIKVRLLHEGTGTITDSDILLASASDAIIIGFNVRPSAKVKALADKEHVDVRSYDVIYHALDDIRDAMVGMLDPTFEEEIIGDAEVRDIFSVPKIGVIGGCYVTSGKIQRNAGVRVLREGVVLYTGKIGSLRRFKDDAKEVASGYECGIGVENFNNIKIGDVLEAFIMNEVAATLGE
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCGR_LARHH
Sequence: MNETFSVTDLSSDQDPAVPHGSHSAPLPSSEDLAKYAMTSPLEIGQHLKRIISANVLVTVFSNHGKSFILTKLLAIDLKSGRFAFDAGSSDDANRQLLKSERNVFVCTPDGIKTQFVTGPVQSFIYDGAPAFLARLPPEVVKLQRREYFRIQTPIANPVVCRVHDYPNPDGSAGIVLPIYDISLGGMSLVLPGEIPGMELGKIFRDCSIDLRQVGSLPVEIEVRNKLVMQQKNGHEQRRIGCQFVNQNSRVQNQLQRYIAQLERERRTLLD
What is the function of this protein?
Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.  Binds 1 c-di-GMP dimer per subunit.  Increasing levels of c-di-GMP lead to decreased motility.
What are the official names of this protein?
Flagellar brake protein YcgR, Cyclic di-GMP binding protein YcgR.
What is the protein family that this protein belongs to?
Belongs to the YcgR family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: SYR_PSECP
Sequence: MTPEELSLAISACLKDAVAAGEIALAESAVPEDVRVERPKNRDHGDWATNIALQLAKQAGTNPREFATILSARLKTISGVSAVDIAGPGFLNITVDAAAAGALAKAIVEAGTQYGTNTALAGHTVNMEFVSANPTGPLHIGHTRWAALGDAIARVLRASGADVTAEYYINDAGSQMNTFANSVYSRLHGLPVPEGGYPGQYIADLGHEVLTAHPDIRELTEVAALPVIRAAAYEAQMKDIKATLADFGVAFDVFFSEQELHDAGAIESAVARLREQGHVFDDGGAVWLRTTDFGDDKDRVMIRANGEPTYFAADAAYYLSKKDRGYTEKIYLLGADHHGYIHRLKAIAAAAGDDPEVNIEVLIGQLVSVNGAKLSKRAGNIIELKDLIDWLGKDAVRYSLARFPADSPLTLDPELLKKNSNENPVFYVQYAHARSRGAARNAVAAGVERQVDGADSFDASLLDHATENELLSYLGSYPSIVAKAAELREPHRVARHLEAIAGAYHRWYDACRIAPMGEEAVTDVNRTRLWLNDATSQVLANGLDLLGVSAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSB_SHIF8
Sequence: MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAALQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: QUEF_VIBA3
Sequence: MSKYSDAKELAGLTLGQKTEYSNQYDASLLQPVPRSLNRNDLALNGELPFVGHDIWTMYELSWLNTNGLPQVAVGEVFIPATSQNLIESKSFKLYLNSYNQTQFENWDQVTERLTQDLSACAGESVIVNVNSVTDYTNQPIVTMEGDCIDNQDIQITSYDFEASLLEGAAGEQEVEETLHSHLLKSNCLITNQPDWGSVEIAYSGKQIDREALLRYLVSFREHNEFHEQCVERIFTDIMKYCAPSKLTVFARYTRRGGLDINPYRSTEQDRPSHNKRMARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNB_ASPFN
Sequence: MAKQVENNNNDHLVQSTDPEHPSNLIPELCRKFYNWGWVTGTGGGTSIRRDDHIFIAPSGVQKELMKPENIFVLQFPTPKYPPSERKYIRKPLDLKPSACTPLFLAAFERGAGCCIHTHSQWAVLVTLLVEREKGPGGYFEISNIEQIKGIPRGKGKGMLGFFDTLRIPIIENTAFEEDLTGSLEKAMEENPDTCAVLVRRHGIYVWGDNVAKAKTQCESLDYLFQLAVEMHKLGIPWVKE
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBC_CUSRE
Sequence: MKTLYSLRRFYHVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVLKALDFGGVYDTWAPGGGDVRKIANLTLSPSLIFGYLLKSPFGGEGWIVSVDDLEDLIGGHVWLGSICILGGIWHILTKPFAWARRAFVWSGEAYLSYSLGALSIFGFTACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLNRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFIGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: RPOB_BACAH
Sequence: MTGQLVQYGRHRQRRSYARISEVLELPNLIEIQTSSYQWFLDEGLREMFQDISPIEDFTGNLSLEFIDYSLGEPKYSVDECKERDVTYAAPLRVKVRLINKETGEVKEQDVFMGDFPLMTETGTFVINGAERVIVSQLVRSPSVYYSGKVDKNGKRGFTATVIPNRGAWLEYETDAKDVVYVRIDRTRKLPVTVLLRALGFGSDQEITELLGDNEYLSNTLEKDNTDSTEKALLEIYERLRPGEPPTVENAKSLLVSRFFDPKRYDLANVGRYKINKKLHIKNRLFNQRLAETLVDPETGEILAAEGTILDRRTLDRILPYLEKNIGFKTAKPMGGVVEGDVELQSIKIYAPESEGERVINVIGNANITRDVKHITPGDILASISYFFNLLYKVGDTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTNAITPQALINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGFEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSFAKVNEFGFIETPYRRVDPETGLVTGHVDYLTADEEDNYVVAQANMKLSEEGEFLDEDIVARFRGENIVTNKERIDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMNPESPIVGTGMEYVSAKDSGAAVICKHPGIVERVEAREVWVRRYVEVDGQTVKGDLDRYKMQKFIRSNQGTCYNQRPIVSVGNEVVKGEILADGPSMELGELALGRNVLVGFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVGEDALRNLDERGIIRVGAEVKDGDLLVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGGGGIILDVKVFNREDGDELPPGVNQLVRAYIVQKRKISEGDKMAGRHGNKGVISRILPEEDMPYLPDGTPIDIMLNPLGVPSRMNIGQVLELHLGMAARYLGIHIATPVFDGAREEDVWGTIEEAGMANDAKTILYDGRTGEPFDNRVSVGVMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGRVKTYEAIVKGENVPEPGVPESFKVLIKELQSLGMDVKMMSSDDTEIEMRDTEDDDDHQSADKLNVEVETTKE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SYVN1_MOUSE
Sequence: MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKVMGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAVDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPQPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAAAPPPTSTAVSRPSGAATTTAAGTSTSAPAPGSVPGPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNPTEETASTVVSAAPSTSAPSSEAPTPSPGASPPIPEAEKPPAPESVGIVEELPEDGEPDAAELRRRRLQKLESPVAH
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation (PubMed:12975321, PubMed:15611074).  Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:12975321, PubMed:15611074).  Also promotes the degradation of normal but naturally short-lived proteins such as SGK.  Protects cells from ER stress-induced apoptosis.  Sequesters p53/TP53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis (PubMed:17170702).  Required for embryogenesis (PubMed:15611074).  Mediates the ubiquitination and subsequent degradation of cytoplasmic NFE2L1 (PubMed:21911472).  During the early stage of B cell development, required for degradation of the pre-B cell receptor (pre-BCR) complex, hence supporting further differentiation into mature B cells (PubMed:29907570).
What are the official names of this protein?
E3 ubiquitin-protein ligase synoviolin, RING-type E3 ubiquitin transferase synoviolin, Synovial apoptosis inhibitor 1.
What is the protein family that this protein belongs to?
Belongs to the HRD1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.