PharMolix/UniProtQA huggingface dataset:
Protein: PKND_CHLAB
Sequence: MQHYDIIRMIGKGGMGEVYLAYDPICSRKVALKRIREDLSDNELLKKRFLREAKIAADLVHPGVVPVFTICSDSDLVYYTMPYIEGYTLKSLLKSVWQCDSLPKDLAEQTSVGTFLSIFHKICSTIEYVHSRGILHRDLKPDNILLGLFSEVVILDWGAALSKEMKEDVLLDLDIPMPGSMFSNMTVPGKIVGTPDYMAPERLRGAPASESTDIYALGVILYQMLTLSFPYRNKKGKKIHVPNHIISPEEVAPHREIPSFLSQVVMRALATDPKERYTSVQALKADIEQHLQGSPQWTPKIALHTQDAECWKFHESILLSKYFPMLEVSPALWYSLAISKIESFSEVRLEYTLLRKGLEGGFGILLPPSENVDHGDFYRGYGFWLHIKKNVLSVSLVRNGLEIQKTSGNIDVNQEKFFIAFEKQNHRLSLNIDHTVWMIHMDYLPGRGGRIGVIIQDITDVCGNIVVLESSGALHVSCLAVPDAFLNEKLYDRAITFYRRIVESFPGRKEGYEAQFRIGIAVLEKAAEEGDQEGFSQALREFSVLHDSVAAPLEYLGKALVYQRLEEYNEEVKSLLLALKRYGQRPEISRVRDHVVDRLHEALYSNHRVSLVFMLLALHVAPESINSSEEEHFLKNLQGKIHDTLFCSLDISPIDFRSSKMELLLSYWSGFTPFLPGLFQRSWDLKDYRALADIFYTAADLGEREFIDVYGNTLRENIQATTFTEDIVEIFPHQLIHFLSALDAIFLHAPVEKIFSDVDILDPVLIIYLFDLFAKDVLIHGKGEQILDAIQVLETYVSPQQRHTYLLPYEILAYLWMKEGKKVHELLSAHYDESFWIEDSHWAFVLYGYWLALTEESSLAYLHLSGCREDHVAPRALIGLFCSPLGICENQWSYQERRNLLLQKFIFFHCLGDDVERDNCRVAYDLLVKERLL
What is the function of this protein?
Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.
What are the official names of this protein?
Serine/threonine-protein kinase PknD.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: SYR_YERPE
Sequence: MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAERVVELLDLTGIASKIEIAGPGFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQVAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLGADRILYYIDSRQHQHLMQAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVERAGKLIAEKNPDMPADELKQVINAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDETSLTLPLVVTEDREATLATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNAESEEIRQSRLKLAMLTAKTLKQGLDTLGIQTVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEP1B_DANRE
Sequence: MTECKAEVTPSASNGHRVFSYTLESHTAAAFAIMNELRRERQLCDVTLRVRYCPLDTHVDFVAHKVVLASSSPVFRAMFTNGLKECGMEVVPIEGIHPKVMGRLIEFAYTASISVGEKCVIHVMNGAVMYQIDSVVQACCDFLVEQLDPSNAIGIASFAEQIGCTELHQKAREYIYMNFSQVATQEEFFTLSHCQLVTLISRDELNVRCESEVFHACVAWVQYDREERRPYVQALLQAVRCHSLTPHFLQRQLEHFEWDAQSKDYLSQIFRDLTLHKPTKVIPLRTPKVPQLIYTVGGYFRQSLSFLEAFNPCSGAWLRLADLQVPRSGLAACVISGLLYAVGGRNNGPDGNMDSHTLDCYNPMNNCWRPCAHMSVPRNRIGVGVIDGMIYAVGGSHGCTHHNSVERYDPERDSWQLVSPMLTRRIGVGVAVINRLLYAVGGFDGTHRLSSAECYNPERDEWRSIAAMNTVRSGAGVCALGNYIYVMGGYDGTNQLNTVERYDVEKDSWSFSASMRHRRSALGVTTHHGRIYVLGGYDGNTFLDSVECFDPETDSWTEVTHMKSGRSGVGVAVTMEPCHKELIPCQC
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination (PubMed:18057000).  Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes (PubMed:18057000).  In response to oxidative stress, different electrophile metabolites trigger non-enzymatic covalent modifications of highly reactive cysteine residues in KEAP1, leading to inactivate the ubiquitin ligase activity of the BCR(KEAP1) complex, promoting nfe2l2/nrf2 nuclear accumulation and expression of phase II detoxifying enzymes (By similarity).
What are the official names of this protein?
Kelch-like ECH-associated protein 1B.
What is the protein family that this protein belongs to?
Belongs to the KEAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly cytoplasmic.
Protein: H1G_STRPU
Sequence: MSAAKPKVAKKARVAPAHPPSSQMVVAAVTALKERGGSSTQAIKKYIAANYTVDMTKQGPFIRRALVKGVASGALVQTKGKGASGSFKLGKKKEGKSDAQKARIAAKKAKLAAKKKEQREKKALKTKARKEKVAAKKAAKKATKKTKKVKKPAAKKAKKPAAKKPAAKKPAAKKAKKPAKKVAKPAKKAAAKPAKKAAKPAKKAAKPAKKAAKPAKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1-gamma, late.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: KLK1_RAT
Sequence: MWFLILFLALSLGRNDAAPPVQSRVVGGYNCEMNSQPWQVAVYYFGEYLCGGVLIDPSWVITAAHCATDNYQVWLGRNNLYEDEPFAQHRLVSQSFPHPGFNQDLIWNHTRQPGDDYSNDLMLLHLSQPADITDGVKVIDLPIEEPKVGSTCLASGWGSITPDGLELSDDLQCVNIDLLSNEKCVEAHKEEVTDLMLCAGEMDGGKDTCKGDSGGPLICNGVLQGITSWGFNPCGEPKKPGIYTKLIKFTPWIKEVMKENP
What are the official names of this protein?
Kallikrein-1, Gamma-NGF, Nerve growth factor gamma chain, PS kallikrein, Pancreatic kallikrein, RGK-1, rK-1, Tissue kallikrein, True tissue kallikrein, True kallikrein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
Protein: PRFA_LISMO
Sequence: MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDGIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN
What is the function of this protein?
Positively regulates expression of listeriolysin, of 1-phosphadidylinositol phosphodiesterase (PI-PLC) and other virulence factors.
What are the official names of this protein?
Listeriolysin regulatory protein.
Protein: FADI_ALIFM
Sequence: MSNSLNSSKYQPLTTRQGDRIAVVSGIRTPFAKQSTAFSTTPAVDLGKLTVKALMDKTDIDPKLIDQVVFGQVVQMPEAPNIAREIVLGTGMNIGTDAYSVTRACATSFQTTANVVESIMAGTIDIGIAGGADSSSVLPIGVSKKLASTLLALSKTKTVYQKLSLLRTLSLKDIAPVPPAVAEYSTGISMGQTAEQMAKSHGITREEQDALAHRSHTLAAKAWKDGLIQDEVMTAFPEPYTVWLDHDNNIRHDSELASYAKLRPAFDRKYGSVTAANSTPLTDGGAALLLMSEKRAKELGYEPLGYIRSFAFSAIDVHHDMLMGPSYATPMALDKAGISLSDLTLIDMHEAFAAQTLSNVKMFASNKFARECLGRDKAIGEIDMDKFNVLGGSIAYGHPFAATGARMIIQTLRELKRRGGGLGLNTACAAGGLGAAMVLEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_COPPD
Sequence: MKRFAVVTLFPDAIDCWLQASVVGRARGRAFDVLYVNPRDFAKDRYRSVDDYMFGGGPGMLMRYDVLKPALDHAKILVQNPLVLALSAGGKVLNQEMCTILSSYEGDIVLLCGHYEGMDDRIFDHVDLEVSVGDYVLSGGELGAAVIMETVIRLLPGFVEKSDNVRKESFTNNLLEEPQFTRPREYEGKEVPEVLLSGHHQRIELWKKEQRIKRTLVQRPDLLTSAKLEPMDLQILRRVLTDMEKVKRAIFGEQSN
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_HELPY
Sequence: MIIERLVGNLRDLNPLDFSVDHVDLEWFETRKKIARFKTRQGKDIAIRLKDAPKLGLSQGDILFKEEKEIIAVNILDSEVIHIQAKSVAEVAKICYEIGNRHAALYYGESQFEFKTPFEKPTLALLEKLGVQNRVLSSKLDSKERLTVSMPHSEPNFKVSLASDFKVVVK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TREA_DROME
Sequence: MFKLPTISLLLVSWSCLVALSQAKTYSLPDLTTDYNNAIPVDEEEAQDPFASCKIYCEGNLLHTIQTAVPKLFADSKTFVDMKLNNSPDKTLEDFNAMMEAKNQTPSSEDLKQFVDKYFSAPGTELEKWTPTDWKENPSFLDLISDPDLKQWGVELNSIWKDLGRKMKDEVSKNPEYYSIIPVPNPVIVPGGRFIEFYYWDSYWIIRGLLYSQMFDTARGMIENFFSIVNRFGFIPNGGRVYYHGRSQPPLLTGMVKSYVDFTNDDKFAIDALDTLEHEFEFFVNNHNVTVKNHSLCVYRDSSSGPRPESYREDVETGEEFPTDEAKELHYSELKAGAESGMDFSSRWFISPTGTNDGNRSALSTTSIVPVDLNAYLYWNAKLIAEFHSKAGNTKKVTEYETKAEKLLLGIQEVLWNEEAGVWLDYDMINQKPRDYYTPTNLSPLWVKAFNISESEKISASVMAYIERNKLDSFPGGVPNTLSYTGEQWDAPNVWAPMQYILVEGLNNLNTPEAKNMSLKWATRWVKTNFAAFSKDRHMYEKYNADEFGVGGGGGEYEVQTGFGWSNGVIIEWLSKHGRDISIGSGCGCLAGEKRQ
What are the official names of this protein?
Trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
Protein: HINT3_ARATH
Sequence: MEARRLAILCSHLNPPGPNPTRDPTLRVSDCSSGSSGDGKVESSTLQNDCVFCKIIRGESPCLKLYEDDMCLCILDTNPLSHGHSLIIPKLHYPTLEETPPSVVAAMCSKVPLISNAIVKATGSDSFNLLVNNGAAAGQVIFHTHIHIIPRKERDCLWASESLRRHSLKLDKEASQLVSCVRRHLCSLPEEQLVQPS
What is the function of this protein?
Possesses adenylylsulfatase activity in vitro.
What are the official names of this protein?
Adenylylsulfatase HINT3, Histidine triad nucleotide-binding protein 3.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MYO1_CHAGB
Sequence: MGITRRAKDKAARAERSGGGGGGSSKPKKATFDTTKKKEIGVSDLTLLRTVSNEAINENLKKRFEGAEIYTYIGHVLVSVNPFRDLGIYTDQVLDSYRGKNRLEMPPHVFAIAESAYYNMKAYKENQCVIISGESGAGKTEAAKRIMQYIANVSGGGETGDIQQIKDMVLATNPLLESFGNAKTLRNNNSSRFGKYLQIHFNAQGEPVGADITNYLLEKSRVVGQIVNERNFHIFYQFTKGASQHYRETFGIQKPETYIYTSRSKCFNVDGIDDLAEYQDTLNAMKVIGLSQAEQDNIFRMLAAILWTGNLVFREDDNGYAAVSDQSVVDFLAYLLEVDPARLVHAITIRVLTPRNGEVIESPANVAQATATRDALAKAIYYNLFDWIVERVNQSLRARQAAANSIGILDIYGFEIFEKNSFEQLCINYVNEKLQQIFIQLTLKAEQDEYAREQIKWTPISYFDNKIVCDLIESVRPPGVFSAMKDATKTAHADPAACDRTFMQSINGMSNPHLTPRQGNFIIKHYAGDVTYTVDGITDKNKDQLLKGILNLVQGSQNKFLHDIFPQQVDQDNRKQPPSAGDRIKTSANALVETLMKCQPSYIRTIKPNENKSPTEYNVPNVLHQIKYLGLQENVRIRRAGFAYRQSFEKFVDRFFLLSPATSYAGEYTWQGSYEAAVKQILKDTSIPQEEWQLGVTKAFIKSPETLFALEHMRDRYWHNMATRIQRMWRAYLAYRAESATRIQRFWRKKRTGAEYLQLRDDGHRVLQGRKERRRMSILGSRRFLGDYLGINASTGPGAQMRNGMQLGNNERAVFSCRGEVLEAKFGRSSKPSPRTIVVTNNKFYVVALVMGQNNQPQVILERSFPLGAIKFISTSTARDDWFSLGVGSQQEADPLLNCVLKTEMFTQMKRVMPGGFNLKIGDTIEYAKKPGKMQLVKVLKDAPTPHDFYKSGAVHTQQGEPPNSVSRPTPKGKPVPPRPITRGKLIKPGGPGGRPSRVPVNRTPQPRPSGASAATTSRPVPQPHPAAAAAAAASVSIPSHTRQKSNSSAVRAPPPPPPAAPPAKPKIMAKVLYDFAGQRENELSIQAGQVIEIVQKENNGWWLAKLSGGQAWVPAAYVEEQEAAPVPAPRPPPPPPAAANGARAKPAAPQPPAKRPAAGRKPAALQGRDSAMSMNGSDSSRSSTPTPSLGGSLADALLARKNAMAKKDDDDDW
What is the function of this protein?
Type-I myosin implicated in the organization of the actin cytoskeleton.  Required for proper actin cytoskeleton polarization.  At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly.  Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity).
What are the official names of this protein?
Myosin-1, Class I unconventional myosin, Type I myosin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch.
Protein: F2612_CAEEL
Sequence: MEIPPGLETTKRKVAHSDEHGFSDQVRVPNVIVMVGLPARGKTYISKKLCRYLKWTGFTTKVFNVGEYRRSDANAADAIHGANASFFSPNNADALKVRAESARRAMEDMADYLNSGTGGVAIFDATNTTKDRRRIIIDFCKKQRLRCFFIESVCDDPAIIDCNVTDVKVNSPDYKGLMTAEQAKEDFMNRIENYKKQYEPLDESEDESLSFIKVINAGRSFKVHQVRGHVQSRVVYFLMNIHLLPRSIYLTRHGQSEYNAMGRLGGDSPLTEDGQKYASALADFFEEEEVPGLRVWCSQKVRAAQTAQHLKPDFHTEYWKALDELDAGICEGLTYEDILQRYPKQADDRATDKYHYRYPSGESYEDVVSRLEPVIMELERQANVLVVSHQAVLRCVLAYFYDRPLSELPYIDIPLHSLVKLTPRAYHCDSTIYALDLESGEWTETSDQLPLCDSPRD
What is the function of this protein?
Synthesis and degradation of fructose 2,6-bisphosphate.
What are the official names of this protein?
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, 6PF-2-K/Fru-2,6-P2ase, PFK/FBPase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphoglycerate mutase family.
Protein: RL17_ANAMF
Sequence: MRHGISCRKFSRPTAHRLSMLANLAVSLIRHERIVTTVAKAKDLRPFVERLVTVGRRLAKKDPVRGRRLLLSKMGGDLDAVNKLLDVLAKRYARRPGGYTRILKNGFRAGDCAPIAIMEFVDRKEGEPKKVAEG
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MNMG_BACAN
Sequence: MGYNAGSYDVIVIGAGHAGCEAGLAAARMGSKTLMLTINLDMVAFMPCNPSVGGPAKGIVVREIDALGGEMGRNIDKTHIQMRMLNTGKGPAVRALRAQADKFSYQHELKKTIEETPNLTLFQGMVERLIVEDGECKGVITQAGAEYTAKTVVITTGTFLRGEIIMGDLKYSSGPNNQQPSITLSEHLEELGFDLVRFKTGTPPRVNSNTIDYSKTEIQPGDDKPRAFSFETTKFIMDQIPCWLTYTSTETHRLIDENLHRSAMYSGMIKGTGPRYCPSIEDKVVRFNDKPRHQIFLEPEGRNTQEVYVQGLSTSLPEDVQRDMLRTIPGLENVEMMRTGYAIEYDAIVPTQLWPTLETKKIKNLYTAGQINGTSGYEEAAGQGLMAGINAACRSLGKKEVILGREDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTEVGHEIGLITEERYERFTNKKLQIEQEKERLSSIIIKPRPEVQELIRNIGGSELKDGIRASDLLRRPEMTYEHIHLLVPSEVELSDEVKEQVEIQIKYEGYIEKSLQQVERMKKMENKKIPVDIDYDAISSLASEARQKLKDVRPLSMGQASRISGVNPADISILLVYIEQGKIARVSNQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCA_BACHK
Sequence: MKHPIHVTSEIGELQTVLLKRPGKEVENLTPDYLQQLLFDDIPYLPIIQKEHDYFAQTLRNRGVEVLYLEKLAAEALVDKKLREEFVDRILKEGQADVNVAHQTLKEYLLSFSNEELIQKIMGGVRKNEIETSKKTHLYELMEDHYPFYLDPMPNLYFTRDPAASVGDGLTINKMREPARRRESLFMEYIIKYHPRFAKHNVPIWLDRDYKFPIEGGDELILNEETIAIGVSARTSAKAIERLAKNLFSRQNKIKKVLAIEIPKCRAFMHLDTVFTMVDYDKFTIHPAIQGPKGNMNIYILEKGADEETLKITHRTSLMEALKEVLDLSELVLIPCGGGDVIASAREQWNDGSNTLAIAPGVVVTYDRNYVSNTLLREHGIEVIEVLSSELSRGRGGPRCMSMPIVRKDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_ERYLH
Sequence: MANVTVIGAQWGDEGKGKIVDWLADRADAVVRFQGGHNAGHTLVVDGTTYKLSLLPSGIVSGTLSIIGNGVVLDPWALKQEVEKLEGQGVTINDDNFAIADNCPLILPIHRDLDGLREAAAGTGKIGTTGRGIGPAYEDKVGRRAIRVCDLEHLDSLEPQLDRLCAHHDALRAGFEEPPVDRERLLGDLREIAPFVLRFAQPVWKRLKKVRKAGAKILFEGAQGVLLDVDHGTYPFVTSSNTVSGTAASGSGLGPGAAGFVLGIVKAYTTRVGSGPFPTELDDEIGQRLGERGHEFGTVTGRQRRVGWFDAVLVRQTCAISGVTGIALTKIDVLDGLDTVKICTGYRLNNNVYDYLPSHAASQAAVEPIYEEMEGWSESTAGARSFADLPANAVKYIQRIQELIECPVALVSTSPERDDTILMRDPFMD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YECN_ECOLI
Sequence: MVSALYAVLSALLLMKFSFDVVRLRMQYRVAYGDGGFSELQSAIRIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRSGMSATWCALLLMVLANLWYMPWELVFSLR
What are the official names of this protein?
Inner membrane protein YecN.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RRP3_CANGA
Sequence: MAGKVGKVSKKSDDVSSLAAKIRARALENQKKMQAASRKDSESDSSDEEVERPAKKQAKDEKVEEPEEEVTFESFAQLNLVPELIQACQNLNFTKPTPIQARAIPPALAGSDVIGLAQTGSGKTAAFAIPILNKLWEDQQPYYACVLAPTRELAQQIKETFDSLGSLMGVRTTCIVGGMNMMDQARDLMRKPHIIIATPGRLMDHLENTKGFSLKNLKFLVMDEADRLLDMEFGPVLDRILKIIPTKGRTTYLFSATMTSKIDKLQRASLTNPVKCAVSNKYQTVDTLVQTLMVVPGGLKNTFLIYLLNEFIGKTVIIFTRTKANAERLSGLCNLLEFSATALHGDLNQNQRTGALDLFKAGKRSILVATDVAARGLDIPSVDIVINYDIPVDSKSYIHRVGRTARAGRSGKSISLVSQYDLELILRIEEVLGKKLPKESVDKNIILTLRDSVDKANGEVVMEMNRRNKEKQARGKGRRGRMMAKENMDREEK
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase RRP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KTHY_HAEIE
Sequence: MKGKFIVIEGLEGAGKSSAHQSVVRVLHELAIQDVVFTREPGGTPLAEKLRHLIKHETEEPVTHKAELLMLYAARIQLVDNVIKPALMQGKWVVGDRHDMSSQAYQGGGRQLDPHFMLTLKETVLGDFEPDLTIYLDIDPIVGLARARGRGELDRIEQMDLDFFHRTRARYLELVKDNPKAVMINAEQSIELVQADIERAVKNWWKSNEK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: CLPS1_RHOPA
Sequence: MSNIDLKPKTKAKAKIKVERPKLHKVILVNDDYTPREFVVSVLKGEFRMTEDQATKVMLTAHQRGVCVVGVFTKDVAETKATRATDAGRAKGYPLLFTTEPEE
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS 1.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: TRMB_SYNS3
Sequence: MRQHVNPLSRFFQLPLELPAPHELFEHPNLPIHLDIGCARGFFLLELAAMQPERNHLGVEIRRPLVQAAQHDRDRQEQHNLHFLFCNANISLEAWMAALPPDQLQLVSIQFPDPWFKQRHRKRRVLQPALLLAIAAALHPGRHLFLQSDVLAVIEPMVALVELSNCFARPKDDPQPWRSSNPLPVATERERYVQEQGQPTYRVLFERTQAELPALRDLEMAWQQVDNSKDAAPTPHG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ERK2_DICDI
Sequence: MSSEDIDKHVLRKYEVLQKIGKGAYGIVWKAIDKKTKQTVALKKIFDAFQNATDAQRTFREIMFLQELHGHENIIKLLNVIKADNDRDIYLVFEHMETDLHAVIRAKILEEIHKQYTIYQLLKALKYMHSANVLHRDIKPSNLLLNSECLVKVADFGLARSITSLESIAEANPVLTEYVATRWYRAPEILLGSTKYTKGVDMWSIGCILGELLGEKAMFPGNSTMNQLDLIIEVTGRPSAEDIEAIKSPFAGTMLESLPPSNPRSLSDMYPSASVDALDLLKKLLQFNPDKRITAEEALAHPFVTQFHNPAEEPHFDRIIKISIDDGQKFPIAEYRNRLYNDIIKKKKEERKKQTNPTKPDTTAPTLST
What is the function of this protein?
Implicated in the relay of the cAMP chemotactic signal and cell differentiation.  Important for receptor-mediated activation of adenylyl cyclase.
What are the official names of this protein?
Extracellular signal-regulated kinase 2, ERK2, Defective in aggregation protein C, MAP kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: TTCA1_FRAP2
Sequence: MTEIKISKTEKKLRHYITKAIADYKLIEKGDKVMLCLSGGKDSFGLLKVLHGLIEDKTYDIDLHVYTLDQSQPGWDDSQLRKYLDNLGVSYEIETKNTYGVVIDKVPEGKTYCSLCSRLRRGNIYRYAKEHKMDKIILGHHRDDLIESLLMSILYQGQIKSMPPKFITQDGENTVIRPMVLVQERDLIEFAKEENFPIIPCNLCGSQENLKRKKVKKLIQDLAHENPKVPSNILNSLSNVLPSHLMDRDLLNIIQN
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase 1, Two-thiocytidine biosynthesis protein A 1, tRNA 2-thiocytidine biosynthesis protein TtcA 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_SHESW
Sequence: MITISDAAQAHFVKLLADQPEGTHIRVFVISPGTAQAECGVSYCPPDAVESDDIELEFNGFNAMVDEKSAPFLEEATIDFVTDQLGSQLTLKAPNAKMRKVSGDAPLVERIEYVIQSEINPQLASHGGNIMLVEITSEGVAVLQFGGGCNGCSQVDITLKDGIEKQLLDMFPGELTGVRDVTDHQHGEHSYA
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: MEND_ECOHS
Sequence: MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: DFPA_LOLVU
Sequence: MEIPVIEPLFTKVTEDIPGAEGPVFDKNGDFYIVAPEVEVNGKPAGEILRIDLKTGKKTVICKPEVNGYGGIPAGCQCDRDANQLFVADMRLGLLVVQTDGTFEEIAKKDSEGRRMQGCNDCAFDYEGNLWITAPAGEVAPADYTRSMQEKFGSIYCFTTDGQMIQVDTAFQFPNGIAVRHMNDGRPYQLIVAETPTKKLWSYDIKGPAKIENKKVWGHIPGTHEGGADGMDFDEDNNLLVANWGSSHIEVFGPDGGQPKMRIRCPFEKPSNLHFKPQTKTIFVTEHENNAVWKFEWQRNGKKQYCETLKFGIF
What is the function of this protein?
Biological function and substrate unknown.  However, it is capable of acting on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases).
What are the official names of this protein?
Diisopropyl-fluorophosphatase, DFPase.
Protein: S100Z_HUMAN
Sequence: MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK
What are the official names of this protein?
Protein S100-Z, S100 calcium-binding protein Z.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
Protein: DNAK_MYCMS
Sequence: MAKEKIIGIDLGTTNSVVSVIEGGQPIILENPEGQRTTPSVVAFKNSDIIVGGAAKRQAVTNPNVVQSIKSKMGTTSKVNLEGKDYSPEQISAEILRYMKNYAEAKLGQKVTKAVITVPAYFNDAQRKATKDAGTIAGLQVERIINEPTAAALAYGLDKQDKEETILVYDLGGGTFDVSILAIGGGSFDVIATSGNNKLGGDNFDEEIIKWLLGKIKAEYNIDLSKEKMALQRLKDEAEKAKINLSSQLEVEINLPFIAMNESGPISFATTLTRSEFNKITKHLVDLTIQPVKDALSAAKKTPSEINEVLLVGGSTRIPAVQELVKSLLNKEPNRSINPDEVVAMGAAVQGGVLAGEVTDILLLDVTPLSLGIETMGGVMTKLIERNTTIPAKRTQIFSTATDNQPAVDINVLQGERAMAADNKSLGQFQLTGIQPAPRGVPQIEVTFEIDANGIVSVSAKDKNTNEEKTITISNSGNLSEAEVERMIKEAQENAANDEVKKKNIELKNKAENYINIIENSLLQAGDKISAEQKEQSQKMVDEIKELVKNENYEALEQKMAELEQAMAQAAEFANKQNESDPNNNSSEQNN
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.