PharMolix/UniProtQA huggingface dataset:
Protein: HUTP_BACC1
Sequence: MLLQGTHRIGRMAMLLALADENESPVLSIPKGWKYCTGKVGSMNSQKVVAAMETAAKSNQVIETDVYRETHALYHAIMEALYGVTRGQIQLADVLRTVGLRFAIVRGTPYDGKKEGEWVAVALYGTIGAPVKGSEHEAIGLGINHI
What is the function of this protein?
Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
What are the official names of this protein?
Hut operon positive regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the HutP family.
Protein: SSRP_NITHX
Sequence: MAEKNERAIKVVAENRKARFNYAIEDTVEAGIALTGTEVKSVRNGKTTIAESYADSKNGEIWLINANIPEYLQANRFNHEPKRPRKLLLHRKQINKLLGAVDREGMTLIPLKLYFNERGRAKLLLAVAKGKKLHDKRESEKKRDWGREKGRLLRARG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PBL3_ARATH
Sequence: MGNCLDSSAKVDSSSHSPHANSASLSSRVSSKTSRSTVPSSLSINSYSSVESLPTPRTEGEILSSPNLKAFTFNELKNATRNFRPDSLLGEGGFGYVFKGWIDGTTLTASKPGSGIVVAVKKLKTEGYQGHKEWLTEVNYLGQLSHPNLVKLVGYCVEGENRLLVYEFMPKGSLENHLFRRGAQPLTWAIRMKVAIGAAKGLTFLHDAKSQVIYRDFKAANILLDAEFNSKLSDFGLAKAGPTGDKTHVSTQVMGTHGYAAPEYVATGRLTAKSDVYSFGVVLLELLSGRRAVDKSKVGMEQSLVDWATPYLGDKRKLFRIMDTRLGGQYPQKGAYTAASLALQCLNPDAKLRPKMSEVLAKLDQLESTKPGTGVGNRQAQIDSPRGSNGSIVQKSPRRYSYDRPLLHITPGASPLPTHNHSPRVR
What is the function of this protein?
May be involved in plant defense signaling.
What are the official names of this protein?
Probable serine/threonine-protein kinase PBL3, PBS1-like protein 3, Protein kinase 2B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Nucleus. Note=Predominantly localized at the plasma membrane.
Protein: MSC6_ASHGO
Sequence: MLFSRASKIRVSQLMRRLQSTAVGRAASRPEMLQLEAKLADVMKDKKDLGRVMAALRETVQGVVESGGLSDRTLLRSNSVTNDLGKLLEQSNKQLRGEIETDTVPPTPYEILVTLVDLKLARRTHYEQVMQYLLANGDAEAALGVWVKYLEFVAQMPQREGAEETYVMAYASIAYFFLGAADVDVLLQLLNREAGQYKDIPLFRIEQLQSQIGLSESNLTKVRENLAAIHKQLLVDKKGYFLDVILPECYYPLLHSYYKRYSDLEGLVDEDLAAGFMINFSRIGKHTLAMKCYNDAVKKAGGKPGVVLKNALLTVVARMGETAINRVNATRRIEAVWNSYFREDDVIDVSSYKALLNALIILKRFDKVQSVWELDIPEELKKDHTLLQTYLEGCAHRTNVSLPELLKQLPEAVTDVNLANAVLLKMANTSGSASMFDSFYDKTFKGPGSLRPTPLTLATRLLMGYATASDPAKFNFFDHTPIPRTMKNAVAEEFLKICSDSEAIKRFYESSKASLKLDVFSSRRVGKIIEASFNIGDWKTAEAIFKDHITTSNAKSQINVHTLLPLIAGFSNLILRNNEPSFLSKLDTYWQLASRVYKTIPFEFLNKTATAVASLCLKEAKLTDEHYNFINAVVMSELARSKKDHGYVLNARIYHSITKDQKISVPPELL
What is the function of this protein?
May be involved in the control of meiotic sister-chromatid recombination.
What are the official names of this protein?
Meiotic sister-chromatid recombination protein 6, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LSPA_SHIDS
Sequence: MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LAC21_ORYSJ
Sequence: MGIAKIPAVLWLLACAVLTFAVAISPAHGGRTRRHYDFFITETNYRRLCHEKSVLTVNGQFPGPTIYARKGDLVIVNVYNHGNKNITIHWHGVDQPRNPWSDGPEFITQCPIRPDGKFTYQVIMSEEEGTLWWHAHSDFDRATVLGAIVVHPKHGDTFPFKRPDKEIPIILGEWWKNDVNHLLEEMKRIGEDVKPSDANTINGQPGDMFPCSRDDTFKVAVEHGNTYLLQVINAGLTNDMFFAVSGHRLTVVGIDARYTKPLTVEYIMIAPGQTMDLLLEANRSLGSKSNSRYYMAARTFITLPVPIPFNNSTATAVVEYYTGDSGAGPPDFPAVLPSLDDVDAAMAFLRQLRSLGSKDHPVHVPTHVDEHMLIDLAINFLPCNATNATDTACKGPKGNTTRFAASLNNVSFVSPAIDVLHAYYYGSGRGVYEDDFPNNPAPVFVNLTGDNDRPGVTKHGAKVKVLEYGTVVEVVFQDTSFESHPMHLHGFAFYVVGLGSGKFDDRRDPATYNLLDPPYQSTVSVPKAGWAAIRFRADNPGVWFMHCHFDRHMVWGMNTVFIVKDGKTPQAQMLPRPPNMPKC
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-21, Benzenediol:oxygen oxidoreductase 21, Diphenol oxidase 21, Urishiol oxidase 21.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: EF2_SULIN
Sequence: MPRYKTVEQVLSLMKDRTRVRNIGIIAHVDHGKTTTSDTLLAASGIISPKVAGEALALDYLSVEQQRGITVKAANISLYHEAEGKGYVINLIDTPGHVDFSGRVTRSLRVLDGSIVVVDAVEGIMTQTETVLRQSLEERVRPILFINKVDRLVKELKLSPQEMLNRLLDIIRQVNNLIDMYGEPEFKEKWMINPQAGNVIFGSAKDKWGFSLPMAQKKGINMKNVIDAYTASDKSKLEELAAQAPINEALLDAAIKFVPNPIEAQKYRIPKIWKGDLDNELAKAMLNADPNGPIVFMITDMKVDPHAGLVATGRVFSGTLRSGEELWLVNAKTSQRILQVSLYMGPTRELAEEIPAGNIAAVLGLDRARSGETAISVGFSNVQGSFERLHYISEPVVTIAVEPKNPKDLTKMIDALRKLSIEDPNLVVKINEETGEYLLSGMGFLHLEVSLQLLRENYGIDVVTTPPIVVYRESIRAKSQVFEGKSPNKHNKFYLSVEPLNDKTIELISNGTIREDMDSKEMAKILRDEASWDYDEAKRIIAIDENVNVFVDLTSGVQHLREVMDTVLQGFRLAMKEGPLAHEPIRGVKVILHDAVIHEDPAHRGPAQIYPAVRNSIFAGFLTSRPTLLEPIQKLDIRVPADLIGNVTAVITRKRGKILDVSQIANMSRITAEIPVSESYDMASELRGSTGGRAFWGTEFSRWAPVPDSILLDVVTKIRERKGLPKELPKVEDFLS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSX_HUMAN
Sequence: MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI
What is the function of this protein?
May play a role in rpe physiology either by detecting light directly or by monitoring the concentration of retinoids or other photoreceptor-derived compounds.
What are the official names of this protein?
Visual pigment-like receptor peropsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CYF_CRYJA
Sequence: MQNRKTYDDWVKKWITQSISVLIMIDIMTRTSIANAYPIFAQQAYENPREATGRIVCANCHLAKKPVEIEVPQSVLPDTVFEAVVKIPYDKQIKQVLANGKKGTLNVGAVLILPEGFELAPPDRIYPEIKEKIGDLYFQNYRPNQKNILIIGPVPGQKYSEIVFPILSPNPATNKAAHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNASATGKVSKIVRKEKGGYQITIDNPSDGRQVVDFVPPGPELLVSEGEFIKADQSLTNNPNVGGFGQENAEIVLQDPLRVQGLLLFLASVVLAQIFLVLKKKQFEKVQLVEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: EXP20_ARATH
Sequence: MDSGLQQLALCLFFILCRLFQATAEDDWKIATATLSRDRDGSSSVATGGACGYGDLRQSSFAGYSAGLSGKLFNRGSSCGACLEVRCVNHIRWCLQGSPSVVVTATDFCPPNSGLSSDYGGWCNFPKEHLELSHAAFTGIAETRAEMIPIQYRRVKCGRRGGLRFSLSGSSHFFQVLISNVGLDGEVVGVKVKGHTTAWIPMARNWGQNWHSSLDLIGQSLSFEVTLKGGKTIASYDVAPPYWRFGMTYQGKQFHS
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Expansin-A20, AtEXPA20, Alpha-expansin-20, At-EXP20, AtEx20, Ath-ExpAlpha-1.23.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: RSMC_CHRSD
Sequence: MSAETPPCQLLERQSEAYRDWLWVAPPHDAWLHTVGGSVWSADATICQAWRARGRPVHADLAPTLTAPVPGAVLFWPKTHALGEWWLLALCAALPEGTPLQVVGEHQGGVKRVLKSLAALGLGCRKVDSARRCTLYATRTARLALSPEAAWTRFEAAGLTLESHPGVFGHGKLDDGTRQLLEVLPTALGDPAGQRVLDVGCGDGILGAWLGVRGAQVAAVDLDAFAVAATRRTFQANGVAGEAWQSDVFGDVSGSYDAIVSNPPFHQQRAIDYGPAERLIREAPARLVPGGRLVLVANAFLPYPRWLEDAFGEFTVLADDRRFRVYQAVKTRR
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCTD5_HUMAN
Sequence: MAENHCELLSPARGGIGAGLGGGLCRRCSAGLGALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQVPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTASEPSEKAKILQERGSRM
What is the function of this protein?
Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (PubMed:18573101).  Does not affect the function of Kv channel Kv2. 1/KCNB1, Kv1. 2/KCNA2, Kv4. 2/KCND2 and Kv3. 4/KCNC4 (PubMed:19361449).
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD5.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, translocated to the nucleus upon interaction with Rep proteins.
Protein: PRA33_HUMAN
Sequence: MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS
What are the official names of this protein?
PRAME family member 33.
What is the protein family that this protein belongs to?
Belongs to the PRAME family.
Protein: RN112_BOVIN
Sequence: MPRSALSVISFCHRLGKQERKRSFMGNSSNSWSHTPFPKLELGLGSRPTAPREPPACSICLERPREPISLDCGHDFCPRCFSTHRVPGCGPPCCPECRKTCKRRKGLRGLGERMRLLPQRPLPAAALQETCAVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGGPHSGKTFLLNHLLQGLPGLASGEGSWPRSAGSGQGFRWGANGLSRGIWMWSHPFLLGKEGRKVAVFLVDTGDVMSPELSRETRTRLCALTSMLSSYQILTASQELKDTDLEHLETFVHVAEVMGRHYGMVPIQHLDLLVRDSSHPSKAWQGHVGDVIQKSSGKYPKVQGLLQGRRARCYLLPAPGRRWASRGHGSSGDDDAGRLRAYVADVLSAAPQHAKSRCPGYWSEGRPAARGDRRLLTGQQLAQEVKNLSGWMGRTGPSCASPDEMAAQLHDLRTVEAAKKEFEEYVRQQDAATKRIFSALRVLPDTMRNLLSAQKDTLLARHGATLLCTGREQTLEALEAELQAEAKAFMDSYTVRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATGAAVVGGGVGAGLAATVGCMEKEEDERVQEGDREPLLQEE
What is the function of this protein?
E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development.  During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins.  Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage.  Exhibits GTPase and E3 ubiquitin-protein ligase activities.  Regulates dendritic spine density and synaptic neurotransmission; its ability to hydrolyze GTP is involved in the maintenance of dendritic spine density.
What are the official names of this protein?
RING finger protein 112, Zinc finger protein 179.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Nucleus, nuclear body. Nucleus, nucleoplasm. Endosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Postsynaptic density. Perikaryon. Cell projection, neuron projection. Note=Predominantly in the nucleus, but some amounts were also found in the cytoplasm. Oxidative stress stimulates its shuttling from the cytoplasm into the nucleus. Recruited to nuclear bodies via its interaction with ZBTB16. Localizes to the cell soma and neuritis and only slightly to the nucleus in the neurons of most brain areas.
Protein: PYY_AMICA
Sequence: YPPKPENPGEDAPPEELARYYTALRHYINLITRQRY
What are the official names of this protein?
Peptide YY-like, PYY.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURD_STRPJ
Sequence: MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTEVELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_SHEB5
Sequence: MAIINMSDLDLQGKRVLIREDLNVPVSNGVVTSDARLRASLPTIELALANGAAVMVMSHLGRPTEGEYNPEYSMQPVVDYLAKALSCPVRLATDYLDGVDVVVGEVVVFENVRFNVGEGKNNEALSKKMAALCDVYVMDAFGTAHRAQASTHGVGMFAPIACAGPLLAQELDALGKALDNPARPMVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGYNVGKSLYEADLIDEAKRLVANAKSRGADIPVPTDVVVAGEFSPIAAATLKSVSEVADGEMIFDIGPDSAEALAKIIASAGTIVWNGPVGVFEFDQFGEGTKRIAQAIADSKAFSIAGGGDTLAAVDKYGIADKVSYISTGGGAFLEFLEGKELPAVAMLEKRGV
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_CAMJJ
Sequence: MSKFKVIEIKEDARPRDFEAFQLRLASPEKIKSWSYGEVKKPETINYRTLKPERDGLFCAKIFGPIRDYECLCGKYKKMRFKGVKCEKCGVEVANSKVRRSRMGHIELVTPVAHIWYVNSLPSRIGTLLGVKMKDLERVLYYEAYIVENPGDAFYDNESTKKVEYCDVLNEEQYQNLMQRYENSGFKARMGGEVVRDLLANLDLVALLNQLKEEMAATNSEAKKKTIIKRLKVVENFLNSNLNANTDSDEAVPNRPEWMMITNLPVLPPDLRPLVALDGGKFAVSDVNDLYRRVINRNTRLKKLMELDAPEIIIRNEKRMLQEAVDALFDNGRRANAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPKLRMDQCGLPKKMALELFKPHLLAKLEEKGYATTVKQAKKMIENKTNEVWECLEEVVKGHPVMLNRAPTLHKLSIQAFHPVLVEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKSVTVPSQDMVLGIYYLSLEKAGAKGSHKICTGIDEVMMALESKCLDIHASIQTMVDGRKITTTAGRLIIKSILPDFVPENSWNKVLKKKDIAALVDYVYKQGGLEITASFLDRLKNLGFEYATKAGISISIADIIVPNDKQKAIDEAKKQVREIQNSYNLGLITSGERYNKIIDIWKSTNNVLSKEMMKLVEKDKEGFNSIYMMADSGARGSAAQISQLAAMRGLMTKPDGSIIETPIISNFREGLNVLEYFISTHGARKGLADTALKTANAGYLTRKLIDVAQNVKITIEDCGTHEGVEINEITADSSIIETLEERILGRVLAEDVIDPITNSVLFAEGTLMDEEKAKILGESGIKSVNIRTPITCKAKKGICAKCYGINLGEGKLVKPGEAVGIVSAQSIGEPGTQLTLRTFHSGGTASTDLQDRQVSAQKEGFIRFYNLKTYKNKEGKNIVANRRNAAILLVEPKIKTPFKGVINIENIHEDVIVSIKDKKQEVKYILRKYDLAKPNELAGVSGSIDGKLYLPYQSGMQVEENESIVEVIKEGWNVLNRIPFASEILVEDGEPVVQNIKAGEKGTLKFYILKGDGLDRVKNVKKGDIVKEKGFFVVIADENDREAKRHYIPRESKIEFNDSEKIDDANTIIASAPKKERKVIAEWDAYNNTIIAEIDGVVSFEDIEAGYSADEQIDEATGKRSLVINEYLPSGVRPTLVIAGKGDKAVRYQLEPKTVIFVHDGDKIAQADILAKTPKAAAKSKDITGGLPRVSELFEARKPKNAAVIAEIDGVVRFDKPLRSKERIIIQAEDGTSAEYLIDKSKHIQVRDGEFIHAGEKLTDGVVSSHDVLKILGEKALHYYLISEIQQVYRGQGVVISDKHIEVIVSQMLRQVKVVDSGHTKFIEGDLVSRRKFREENERIIRMGGEPAIAEPVLLGVTRAAIGSDSVISAASFQETTKVLTEASIAGKFDYLEDLKENVILGRMIPVGTGLYGEQNLKLKEQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SYDND_GEOSW
Sequence: MFGRTYYCGEITEKAIGEKVVLKGWVQKRRDLGGLIFIDLRDRTGIVQVVFSPEVSKEALNVAEKVRNEYVLSVEGTVVAREEGTINPNLPTGKIEIQAERITIINEAKTPPFVITDQTDVAEEVRLKYRYLDLRRPVMFRTLQLRHRVTKAIRDFLDGEGFLEVETPILTKSTPEGARDYLVPSRVHPGEFYALPQSPQIFKQLLMVAGFERYYQIARCFRDEDLRADRQPEFTQIDIETSFMSQEEIMQLTERMMAYVMKMAKGIDISLPFPRMSYDEAISRYGSDKPDTRFGLELVDVSEIVKNSSFKVFAGAIANGGQVKAINVKGAADQYSRKDIDALAEFVARYGAKGLAWLKVEEDGLKGPIAKFFTEEEQNGLIRTLEAEAGDLLLFVADHKTVVANALGALRVKLGKDLNLIDETKFNFLWITDWPLLEYDEEDGRYYAAHHPFTMPVREDLPQLETNPEKVRAQAYDLVLNGYELGGGSMRIFEREVQEKMFRALGFTEEEARKQFGFLLEAFEYGTPPHGGIALGLDRLVMLLAGRTNLRDTIAFPKTASASCLLTEAPSPVSEQQLEELHLVVNSEKKSEQY
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJBC_SCHPO
Sequence: MSDSFDAAASHFHARSSVNDSSFHLSRQEEAELLEGALHAPYPEELLFDDDEYTAKTQYDGPRYAMPTMFYPNKPTPGWPLNYVFGNERSRFEKILSNFVLRNLMLQVLAPCFVLLWCAVPMPRYEDSQGTVRIRFWFFLIFYYGIYNAVGLLWITKLFHIYSVNWCPSKLGGTITYILFWMFSLLVGSLVVYFTAWRQITFTWITLMFISMIIPIGISFSKLWKKHSRRTAQFLTQLALLEPEVRSNAVLETIGWKDAYAHYSWFIVVLLVTLLVYIVGEYLTNLYMSTLPHSSTVAIMYVYSWTGTVSLCNLVSSWILNTKTHSYALVTVFKLYFELTLQVYVRNLYARLESPQQFVLVQIASSLTMMSVIPLITMSRTVFRLNVLMTKSMDSYVVYRKNMGRNFYVKCVASNVSMLSFLGWSLILHFGSNAPLYPYFSFSKEEPYSFKLTFYASTAVWISEMVASYLTRLIMRKFYDFEVALEAIRDFVEYPDMIPTFIAVSIHVLQNVVFSIISLHF
What are the official names of this protein?
Uncharacterized protein C553.12c.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FLAV_MEGG1
Sequence: MPKALIVYGSTTGNTEGVAEAIAKTLNSEGMETTVVNVADVTAPGLAEGYDVVLLGCSTWGDDEIELQEDFVPLYEDLDRAGLKDKKVGVFGCGDSSYTYFCGAVDVIEKKAEELGATLVASSLKIDGEPDSAEVLDWAREVLARV
What is the function of this protein?
Electron-transfer proteins that function in various electron transport systems in microorganisms.  Functionally interchangeable with ferredoxin.
What are the official names of this protein?
Flavodoxin.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: HIS1_PYRFU
Sequence: MRFVLPKGRLYQDSIKVLELAGIKVPKRDERALIWGDGNNEFLLARAFDVPVYVEHGIDIGIAGSDVVEERGSDVFIPLELPFGKCRLSIAVPKEKVVDPENMDGYKIATKYPNITKRYFENLNIEVEVIKLHGSIELAPRIGIADAIVDIVETGNTLRSNGLVEVAKIMDVSALLLVNRISQKMFFEEINSFITKIRRSVYGH
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSCC_ASPFU
Sequence: MASRLPILIIGAGISGLTTARLLTNSGIPNIVFEASSPDRRQGFAISLREWGYTILLSALGDLPLRSLTRGVAPDREIGGSGWIDQAVWDNGTAKKLFVPDANSSTKELIVRANRNALRRWIADCGEEELDVRYGHRLKRVEGSLGDVRVEFENGAFYRGLMVVAADGVNSTVRSQVLAHVQPETVPAVLYHGEFQLPRADFDRLFRPHTGESNILAGVGDGFNTPFAVCNMTKTHVHMDWSYSRPVRGSGEDDPLYRPNLASEEAKRIPTALVEELASRDLAEPWSLFLNGEAIQHHRVFHWAVRCVSVTREDMQRAVGRGVAFVGDSWHAMPIFGGEGGNHALADGIELAGAIAAGATGDLGTAIGNYYDQAWKRSQDAVRRSKQRFYTLHRPMAEWRELSKKKPL
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of neosartoricin, a prenylated anthracenone that exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576, PubMed:23368997).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (PubMed:23368997).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (PubMed:23368997).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (PubMed:23368997).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (PubMed:23368997).  There is no gene encoding O-acetyltransferase in the nsc gene cluster; thus, the last step of 2-O-acetylation leading to neosartoricin may be catalyzed by an unidentified O-acetyltransferase (PubMed:23368997).
What are the official names of this protein?
FAD-dependent monooxygenase nscC, Neosartoricin biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: H110_CHICK
Sequence: MSETAPAAAPAVAAPAAKAAAKKPKKAAGGAKARKPAGPSVTELITKAVSASKERKGLSLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFRLSKKPGEVKEKAPRKRTPAAKPKKPAAKKPASAAKKPKKAAAAKKSPKKAKKPAAAATKKAAKSPKKATKAAKPKKAATAKSPAKAKAVKPKAAKPKAAKPKAAKAKKAAAKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1.10, Methylated DNA-binding protein 2-H1, MDBP-2-H1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.