PharMolix/UniProtQA huggingface dataset:
Protein: GB_HHV6U
Sequence: MSKMAVLFLAVFLMNSVLMIYCDPDHYIRAGYNHKYPFRICSIAKGTDLMRFDRDISCSPYKSNAKMSEGFFIIYKTNIETYTFPVRTYKKELTFQSSYRDVGVVYFLDRTVMGLAMPVYEANLVNSHAQCYSAVAMKRPDGTVFSAFHEDNNKNNTLNLFPLNFKSITNKRFITTKEPYFARGPLWLYSTSTSLNCIVTEATAKAKYPFSYFALTTGEIVEGSPFFNGSNGKHFAEPLEKLTILENYTMIEDLMNGMNGATTLVRKIAFLEKADTLFSWEIKEENESVCMLKHWTTVTHGLRAETNETYHFISKELTAAFVAPKESLNLTDPKQTCIKNEFEKIINEVYMSDYNDTYSMNGSYQIFKTTGDLILIWQPLVQKSLMFLEQGSEKIRRRRDVGDVKSRHDILYVQLQYLYDTLKDYINDALGNLAESWCLDQKRTITMLHELSKISPSSIVSEVYGRPISAQLHGDVLAISKCIEVNQSSVQLHKSMRVVDAKGVRSETMCYNRPLVTFSFVNSTPEVVPGQLGLDNEILLGDHRTEECEIPSTKIFLSGNHAHVYTDYTHTNSTPIEDIEVLDAFIRLKIDPLENADFKVLDLYSPDELSRANVFDLENILREYNSYKSALYTIEAKIATNTPSYVNGINSFLQGLGAIGTGLGSVISVTAGALGDIVGGVVSFLKNPFGGGLMLILAIVVVVIIIVVFVRQRHVLSKPIDMMFPYATNPVTTVSSVTGTTVVKTPSVKDVDGGTSVAVSEKEEGMADVSGQVSDDEYSQEDALKMLKAIKSLDESYRRKPSSSESHASKPSLIDRIRYRGYKSVNVEEA
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: PURT_PROMT
Sequence: MNVFPKKIMLLGSGELGKEVAIAAKRLGCYVIACDRYNDAPAMQIADQFNVFNMNNGSELKEVIYKCNPDIIIPEIEALAVDVLKEIEQKITVIPNSRATAITMNRDKIRDLASNELNIRTAKFSYAVNQSELDLHAETIGYPLLIKPVMSSSGKGQSLVKNKNDLAQAWNLAIEKSRGKSNKIILEEFIDFDLEITLLTIRQSNGKTLFCAPIGHEQKNGDYQCSWQPAELTESVLEKAQQIAKRVTDNLGGVGLFGVEFFIKGEEVIFSELSPRPHDTGLVTLISQNLNEFELHLRAVLGIPIPEIVCHEASASRVILASMETTDVAFTGLEQALSQSNTNVFMFGKPSSTEGRRMGVAVAKAETIDEARIKADNAAQSVQFINE
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: MATK_IMPCA
Sequence: MEEFKGYLELDRSQQQDFLYSLSFQESIYTLAHDHGLNRLILNADSDKKYSLLIVKCLITQMYQQNLLIFSANEPKQNLFFGHNTDLYCRILFEAFTVILEIPFSLRERPFIERKEMVQFLNLRSIHSIFPFLEDKFSHSNYVVDILLPHSIHLEILVQTLRYWVKDASSLHLLRFFLHQYHNWNSFIIPKQSRFFFXKKKKBQRLFFFLYNSKVCEYESIFIFLRNQSVHLRSISSEAFLERIYFYEKMEYFLEVYAKDFQAFFWLFKDLFMHYVRYQGKCILVSKGTSFLMSKWKYYLVNLWQSCFYMWSQPGRVQINQFSNYSLDFLGYLSSVRRNPSMTWSQMLENSFLISLVIKKFDTRVPTIPLIRSLSKAKFSNILGYPISKASWADFSDSNIIDRFGRIYRNLSHYHSGSPKKTSLYKVKYILRLSCVRTLARKHKSKVRSFLKRFGSGLLEEFFMEEEQVLTLNLQKISFTLRRFYGRQIWYLDIFCINDLAKSE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EXUT_ECOLI
Sequence: MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPAIEVAQETHNDPAPQH
What is the function of this protein?
Transport of aldohexuronates such as D-glucuronate and D-galacturonate (PubMed:783117, PubMed:6343797).  Under anaerobic conditions, can play a critical role as a D-glucose transporter in the absence of sugar-PTS system (PubMed:32038601).
What are the official names of this protein?
Hexuronate transporter, Aldohexuronate transport system.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Phthalate permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YIDC_TRIL1
Sequence: MEKRTILAVVLSIGVFYLFSFFYGPEKKPAPAAVSVPVKTENVGAAPAVSVQAAAIAPVVVPKIVSAADVTVETERYTAVFSGVGASLKSLTLKGFRETNKPGAAQVKLLANADPALPSFSTRGVGFALSAQAAYSPNVSSLKLLSGEKKQLVFTYVDAQGFVVRKTYTFDGTGYGIALETQLVNNSAAPIAGAFQYLFTSPFDPPQKDGRYETYGSSLYADGSLHTDAPKNVASATKKYDKGITWAAINDKYFLSALLSVNNSIASVELKKSAAGYLESDISTPAFSVAPGQAVTVAHKLFIGPKEIDILKAQGSSLEQSLDLGWFSAIAKPMLYSLKFFYRYVGNYGIAIIIITVILKIFFFPLTHKSYKSMKEMGKLQPKMAALKEKYKNDKDAMNRAVMELYRDHKVNPLGGCLPMIVQIPVFFALYKALMYSIELRHAPFMFWITDLSDKDPFYVTPVIMGVTMFIQQKMTPSNMDEMQQKIMLGLPVIFTFMFLSFPSGLVLYWLINNILTIGQQAYINKLVKD
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRAY_HISS2
Sequence: MLVWLAEYLHQYQSVFNVFSYLTVRAILALFTALLLSLWIGPKVIRRLQILKFGQEIRNDGPDSHLSKKGTPTMGGIMILFAIGVSTLLWANLANPYVWFCLFVLFGYGAVGFVDDYRKITRKNTAGLVARWKYFWLSVIALISAFGMYAIGKDTDATRLVVPFFKDVMPQLGLFYIVLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAAAFALIAWATGNIEWSKYLYIPYIKHTSELVIFCTAIVGAGLGFLWFNTYPAQLFMGDVGSLALGGVLGTIAVLVRQEFLLVIMGGVFVVETLSVILQVGSYKLRNGKRIFRMAPIHHHYELKGWPEPRVIIRFWIISLMLVLLGLITLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS3_BURO0
Sequence: MNTETKSLPAWLDKVRWDDNGLVPVIAQEASTNDVLMFAWMNREALAKTIETQRAVYYSRSRKRLWFKGEESGHVQHVHEVRLDCDEDVVLLKVEQVSGIACHTGRHSCFFQKFEGTVDGGDWVAVEPVLKDPEHIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
Protein: MYG_PENEL
Sequence: MGLSDGEWQLVLNVWGKVEADLAGHGQDILIRLFKGHPETLEKFDKFKHLKTEADMKASEDLKKHGITVLTALGAILKKKGHHDAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPAEFGADAQGAMNKALELFRKDIAAKYKELGFHG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PANC_SODGM
Sequence: MLIIETPPTLRQTVKQWSQEHKRIALIPTMGNLHEGHMALIDAGRARADKVVVSVFVNPMQFDRPEDLAAYPRTLQEDCEQLTRRGVDMVFAPATGVIYPDDLASQTFVDVPRFANILEGESRPGHFRGVATIVSKLFNLVQPDVACFGEKDFQQLAFIRQLVRDMSYDIEIIGVPTVRAADGLALSSRNGYLSAEERRLAPQLNQVLMRLVAQLREGERHIDGLLTSATEQLLQAGLRPDTLVIRDAQTLQPLTVDSRRAVVLFTAWLGKARLIDNAQVDLIS
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PALY_RHOTO
Sequence: MAPSLDSISHSFANGVASAKQAVNGASTNLAVAGSHLPTTQVTQVDIVEKMLAAPTDSTLELDGYSLNLGDVVSAARKGRPVRVKDSDEIRSKIDKSVEFLRSQLSMSVYGVTTGFGGSADTRTEDAISLQKALLEHQLCGVLPSSFDSFRLGRGLENSLPLEVVRGAMTIRVNSLTRGHSAVRLVVLEALTNFLNHGITPIVPLRGTISASGDLSPLSYIAAAISGHPDSKVHVVHEGKEKILYAREAMALFNLEPVVLGPKEGLGLVNGTAVSASMATLALHDAHMLSLLSQSLTAMTVEAMVGHAGSFHPFLHDVTRPHPTQIEVAGNIRKLLEGSRFAVHHEEEVKVKDDEGILRQDRYPLRTSPQWLGPLVSDLIHAHAVLTIEAGQSTTDNPLIDVENKTSHHGGNFQAAAVANTMEKTRLGLAQIGKLNFTQLTEMLNAGMNRGLPSCLAAEDPSLSYHCKGLDIAAAAYTSELGHLANPVTTHVQPAEMANQAVNSLALISARRTTESNDVLSLLLATHLYCVLQAIDLRAIEFEFKKQFGPAIVSLIDQHFGSAMTGSNLRDELVEKVNKTLAKRLEQTNSYDLVPRWHDAFSFAAGTVVEVLSSTSLSLAAVNAWKVAAAESAISLTRQVRETFWSAASTSSPALSYLSPRTQILYAFVREELGVKARRGDVFLGKQEVTIGSNVSKIYEAIKSGRINNVLLKMLA
What is the function of this protein?
Catalyzes the non-oxidative deamination of L-phenylalanine and L-tyrosine to form trans-cinnamic acid and p-coumaric acid respectively with similar efficiencies.  Facilitates the commitment step in phenylpropanoid pathways that produce secondary metabolites such as lignins, coumarins and flavonoids.
What are the official names of this protein?
Phenylalanine/tyrosine ammonia-lyase, Bifunctional phenylalanine ammonia-lyase, Bifunctional PAL.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_EXIS2
Sequence: MAKRKQNVRSKRKVKKNIESGIVHIRSTFNNTIVTITDMQGNAISWATAGNMGFKGSRKSTPFAAQLASETAAKTAMDNGMRTVEVNVKGPGAGREAAIRALQAIGLEVTAIRDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: NUSB_CITK8
Sequence: MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDVLYFRELLSGVATNSAYLDGLMKPYLSRLLEELGQVEKAVLRIALFELSKRSDVPYKVAINEAIELAKTFGAEDSHKFVNGVLDKAAPVIRPNKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: HIS6_SALPC
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYADEGADELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIRSIDDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWFDDATGKYHVNQYTGNENRTRVTQWETLDWVQEVQQRGAGEIALNMMNQDGVRNGYDLTQLKKVRDVCRVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLAGQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_MYCVP
Sequence: MSRSVLVLNSGSSSVKYAVLEPDSGVLVADGIVERIGEEGAERAVTDHAAAMQVVFDSLASDGHRLDDLGLVAVGHRVVHGGQDLYRPTVVDDATIARLKELSPLAPLHNPPAILGIEVARKALPDLPHVAVFDTAFFHDLPPAAATYAIDAEVAGSWHIRRYGFHGTSHQYVSEQAAAFLNVPLESLSQIVLHLGNGASASAILGGRPVETSMGLTPMEGLVMGTRSGDVDPGVIFYLWRTAGMSVEDIEAMLNRRSGVRGLGGEIDFRVLHQRIESGDAAAQLAYDVYIHRLRKYVGAYLATLGSVDVITFTAGVGENDAAVRRDVLSGLTAFGIELDEHLNASPARTARRISPDGAPITVLVVPTNEELAIARACAGVLGGRLGHG
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_STRA1
Sequence: MYDYIKGKLSKITAKFIVVETAGLGYVIYVANPYSFSGYVNQEVTIYLHQVIRDDAHLLFGFHTENEKEIFLNLISVSGIGPTTALAIIAVDDNEGLVSAIDNSDIKYLTKFPKIGKKTAQQMILDLSGKFVEASGESATSRKVSSEQNSNLEEAMEALLALGYKATELKKVKAFFEGTNETVEQYIKSSLKMLMK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CHSTE_MOUSE
Sequence: MFPRPLTPLAAPKSAETLGRTPRRAPLGRARAGLGGPPLLLPSMLMFAVIVASSGLLLMIERGILSEMKPLPLHPPSHKGAAWSGTDPKPRGLSLDAGDSDLQVREDIRNRTLRAVCGQPGMPRDPWDLPVGQRRTLLRHILVSDRYRFLYCYVPKVACSNWKRVLKVLAGILNNVDVRLKMDHRSDLVFLADLRPEEIRYRLQHYFKFLFVRDPLERLLSAYRNKFGEIREYQQRYGAEIVRRYRAGAGPSPAGDDVTFPEFLRYLVDEDPEHMNEHWMPVYHLCQPCAVHYDFVGSYERLEADANQVLEWVRAPPHVRFPARQAWYRPASPESLHYHLCNVPRALLQDVLPKYILDFSLFAYPLPNVTKEACHQ
What is the function of this protein?
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate.  Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate.  Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl.  Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences.  Has preference for partially desulfated dermatan sulfate.  Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA.  Appears to have an important role in the formation of the cerebellar neural network during postnatal brain development.
What are the official names of this protein?
Carbohydrate sulfotransferase 14, Dermatan 4-sulfotransferase 1, D4ST-1.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RL22_GLAP5
Sequence: METIAKHRYARTSAQKARLVADLIRGKKVSAALEILTFTNKKAAALVKKVLESAIANAEHNDGADVDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MTAA_SYNP2
Sequence: MEKKLISLFSGAGGMDIGFHAAGFSTAVAVEQDPSCCNTLRLNMPDTPVIEGDITSITTQVILEAAKVNPLEIDLVIGGPPCQSFSLAGKRMGMDDPRGMLVLEFLRVVREALPKCFVMENVKGMINWSKGKALEAIMTEASQPIKYAGKEYKYAVSYHVLNAADFGVPQFRERVFIVGNRLGKTFQFPEPTHGPSNQARQIDLFGKQLKPYKTVQDAISTLPPATPPSAMALRVSQTIKDRIKNHGY
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-CYCGRG-3', methylates C-1 on both strands, and protects the DNA from cleavage by the AquI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.AquIA, M.AquiA, Cytosine-specific methyltransferase AquI subunit alpha, Modification methylase AquI subunit alpha, M.AquI subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: SURE_METKA
Sequence: MRILITNDDGIASPGLRAAVRACRSVGEVTVVAPATQQSGVGRSISLLEPVRVEEIEVEGVDALAISGTPADAVLIGAFSIMDEPPDLVVSGINLGENVSADVTTSGTVGAALEAYGNGIPAIAISQEVRDARARVDNNAKNVDFTLAIRVLKALLEAIRGANWEGVLNVNVPDPDRWNGEIKVVPLAFTMYRPRIEKRYDPRGRRYYWIDGEIIQDPPEGTDLYELQRGSIVITPLTTDVTGDLDAAENVIKELRRALRG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1081_RICFE
Sequence: MRKQQIPTLSTSALDKSPGPGSPDSDIEMKSTSVKSDIDELAKLLKDKTKDGIAIFNSALKVCIENNPNALLHEAAEHGKKKLVVEILKVNRDSINSTTPQGLSVLHSAVAGVNNKKEIIEILLNEEPILVTKKDALGLTPSCYNTSTEILKILQEYERNVIDQALIKPAKYVPITPPKCLPIEVVQSNLEKAFEEYMGYKLVGQTNPTNSDEF
What are the official names of this protein?
Putative ankyrin repeat protein RF_1081.
Protein: NUOB_ALBFT
Sequence: MIEGILKEGFITTSYDSVMNWAKTGSLWPMSFGLACCAVEMMHAANARYDISRFGAEVFRASPRQSDLIIVAGTLCNKMAPAFRKVYDQMSEPRRVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALLYGIIQLQHKIRRTQTIARA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PG144_VARV
Sequence: MSYLRYYNMLDDFSAGAGVLDKDLFTEEQQQSFMPKDGGMMQNDYGGMNDYLGIFKNNDVRTLLGLILFVLALYSPPLISILMIFISSFLLPLTSLVITYCLVTQMYRGGNGNTVGMSIVCIVAAVIIMAINVFTNSQIFNIISYIILFILFFAYVMNIERQDYRRSINVTIPEQYTCNKPYTAGNKVDVDIPTFNSLNTDDY
What is the function of this protein?
Envelope protein which participates in virus morphogenesis.  Needed for an early step in viral crescent membrane formation by interacting with OPG125 scaffold protein.  Its interaction with OPG125 scaffold protein leads to the formation of rigid, crescent-shaped membranes that assemble around the cytoplasmic virus factory.  Acts as a membrane anchor for the protein OPG154.  OPG144-OPG154 virus envelope protein might be involved in fusion or attachment, and can further associate with OPG153.
What are the official names of this protein?
Virion membrane protein OPG144 precursor, 23 kDa late protein.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG144 family.
Protein: SURE_SHESA
Sequence: MIRILVSNDDGVNAPGIRALTEALAEIATVMTVAPDRNCSGASNSLTLTNPLRINRLDNGYISVHGTPTDCVHLAIRELCDGEPDMVVSGINAGANMGDDTLYSGTVAAAMEGRFLGFPAVAISLNGKALKHYHTAAVYARRIVQGLLAHPIASDQILNINVPDLPLDEIKGIRVTRLGARHKAEGIVRTQDPAGKEIFWLGPPGVEQDASEGTDFHAVAHGYVSITPLTVDLTAHRQLSVLQDWVDKI
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_STAES
Sequence: MAISAKLVKELREKTGAGMMDCKKALTETDGDIDKAIDYLREKGIAKAAKKADRIAAEGLVHVEVKDNEAAIVEINSETDFVARNEGFQELVKEIANHILDSKVETVDALMESKLSSGKTVDERMKEAISTIGEKLSIRRFSIRTKTDNDAFGAYLHMGGRIGVLTVVEGTTDEEAAKDVAMHIAAINPKYVSSEQVSEEEINHEREVLKQQALNEGKPEKIVEKMVEGRLRKYLQEICAVDQNFVKNPDETVEAFLKAKGGKLTDFVRYEVGEGMEKREENFAEEVKGQMK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_ECOK1
Sequence: MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGISWQQRLGDWWQDDKPWLREAPRRESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRISDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPKSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETTLVDAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RL3_BURMA
Sequence: MSLGLVGRKVGMTRIFTAEGDSIPVTVLDVSDNRVTQIKTVETDGYTAVQVAFGSRRASRVTKPLAGHLAKAGVEAGEILKEFRIEADKAAELSNGAVIGPDLFEVGQKVDVQGVSIGKGYAGTIKRYNFGSGRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHMGDETVTVQNLEIARIDADRKLLLVKGAVPGAKGGKVFVTPAVKTRAVKGAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: FKBA_BUCAP
Sequence: MIVFLLKRILLLYLIFFVPKSFSENLPFFKIKSYSEKKEFFQNDNEKVGYSLGVSLGNYVNESFERQKKMGINLDKYNILLGVQDAISGNLKLSNEEISTILQKLEKNLKNAAKIEFEKSEKENLIQGKLYMKKFSEMKGVSKTSSGLLYIIDKLGEGEEIKTKNAEITVHYKGSLINGTEFDSSYKRGKPITLMLKDVILGWQEGLKYIKKGGKIKLIIPPNLGYGSNRINEIPANSILIFDIELLDIKNI
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.