PharMolix/UniProtQA huggingface dataset:
Protein: CA1D_CONGE
Sequence: MGMRMMFTVFLLVVLAATIVSFTSDRASDGRNVAAKAFHRIGRTIRDECCSNPACRVNNPHVCRRR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin reversibly blocks alpha-3-beta-2/CHRNA3-CHRNB2 (IC(50)=3. 1-5. 1 nM), alpha-7/CHRNA7 (IC(50)=4. 5-5. 1 nM), and alpha-4-beta-2/CHRNA4-CHRNB2 (IC(50)=128. 6-390 nM) nAChRs.
What are the official names of this protein?
Alpha-conotoxin GID.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLPG_ECOLI
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CMOB_CAMC1
Sequence: MDLSKFNEQQKQILNRIENLANFDCEFSLSDSVNVKFKNLDQAKKDEIYNLALSLKPWRKGPFLLDDIYIDSEWQSFIKFNILAPHLNLAGKCVADVGCNNGYYMFKMLSYDPKSITGFDPSVHTYLQFKFLNKFIRSNINYQLLGVESLPEYAAKFDTIFCLGVIYHRSDPIKMLKELKTALNTGGELFLDTMYIDMDGDFALSPKDRYSKIPNIYFVPTLSALQNWCERAKFKDFTLLETKATDLNEQRKTQWIDGESLSNFLDPADNTKTIEGYPAPKRAYVRVKI
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: RL28_CHLFF
Sequence: MSRKCPLTGKRPRRGNSYTIRGIAKKKKGIGLKVTGKTKRRFFPNMVTKRLWSTEENKFLKLKISASALRLIDKLGLEKVIARAKSKGF
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ITAL_HUMAN
Sequence: MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGAPGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEAGDPGCLKPLHEKDSESGGGKD
What is the function of this protein?
Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4.  Integrin ITGAL/ITGB2 is a receptor for F11R (PubMed:11812992, PubMed:15528364).  Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL (PubMed:29100055).  Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.  Contributes to natural killer cell cytotoxicity (PubMed:15356110).  Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992).  Required for generation of common lymphoid progenitor cells in bone marrow, indicating a role in lymphopoiesis (By similarity).  Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590).
What are the official names of this protein?
Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ARF_ENCCU
Sequence: MGNMMSKVNNLLYTKLRGLFSGQSERSITMIGLDGAGKTTLLLYLQTGEVHQTVPTLGFNCENVTLGSMKFQVWDIGGQNSFMRFWHQYINEGCGIIYMVDCADPQRFGKSGEELWRILNILNSPRPLLVLANKIDLIREHERSEVVKSIRNEFNLERYNGPSQVVPISVLQAGSMTSANDENGREIIDAFRWLNKELEKMPRAEAL
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: PSAJ_PIPCE
Sequence: MRDIKTYLSVAPVLATLWFGSLAGLLIEINRLFPDALVFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HYIN_PSESY
Sequence: MREMITLESLCRALADEQIAAEELRERALDTEARLTLLNCFIREGDAVSQFGEADQARKGTSLWGVPVSFKDNICVRGLPLTAGTRGMSGFIADQDAAIVSQLKALGAVVAGKNNMHELSFGVTSINPHWGAVGNPVAPGYCAGGSSGGSAAAVASGIVPLSVGTDTGGSIRIPAAFCGITGFRPTTGRLSTAGIIPVSHTKDCVGLLTRTAGDAEFVYGLLSGKQQSFPLNRTGPCRIGLPVSMWSDLDGEVERACINALSLLRKTGFEFVEIDDADIVELNQTLTFTVPLYEFFADFAQSLLSLGWKHGIHHIFAQVDDANVKGIINHHLGEGAIKPAHYLSSLQNGELLKRKMDELFARHHIKLLGYPTVPCRVPHLDHADRPEFFSQAIRNTDLASNAMLPSITIPVGPEGRLPVGLSFDAPRARDAFLLSNVSLIEKVLKG
What is the function of this protein?
Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).
What are the official names of this protein?
Indoleacetamide hydrolase, IAH, Indole-3-acetamide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: RL3_CLOB1
Sequence: MKKAILGKKLGMTQIFNENGKVIPVTVIEAGPCTVIQKKTVEKDGYEAIQVAFGDIREKLRNKPIKGHFAKAGVSVKRHIKEFKLEDSNSLEIGQEIKADVFEAGERVDISGVSKGKGFQGTIRRWNAHRGPMSHGSKFHRAVGSMGASSDPSRTFKNKRMPGHMGNVNTTVLNLEVVRIIPEKNLILIKGGVPGPNKGLVQIRNTVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GL812_ORYSJ
Sequence: MASSSLFLLGALLVLASWQAIVAYDPSPLQDFCVADMNSPVRVNGFACKNPMDVSSEDFFNAAKFDMPRNTFNKLGSNVTNLNVMEFPGLNTLGISLARIDYAPMGVNPPHIHPRATELLTVLEGTLYVGFVTSNPNKLFSKVVCKGDVFVFPKAMIHFQMNLDHDKPAVAQSALSSQNPGVITIASAVFGSQPPISDDVLTKAFQVEKKLIDWLQSQFWENNY
What is the function of this protein?
Plays role in broad-spectrum disease resistance.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 8-12.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: THIM_METMA
Sequence: MKNPLKTIRETKPLVHHITNWVTIYDCANITRAFGALPVMAHAPEECADMTGISSALVLNIGTLTSEIIDSMLLSAAAANKKKIPVVLDAVGVGATRFRDEMAAKILGSVRVDIIKGNYSEIAKLAGENAETKGVESTSISADPQKVAKEFAKSSSSVVVMTGKEDVISDGNRTFVVKNGHELMGSIVGTGCMAASIIGSFASVNPDYCDAAKDALCYFGAAGELAAKNSAGPGSFKVNLYDEVFNLSDEKVQAMMKVEEL
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: NIA_USTMA
Sequence: MTISTTSSSTSSKTSSEKGDDLKGFSSSSSPASSRSSSATTPEPSSPTVLAAKTIESIDPFQPRKDYNENVLPAIPATEAVQPLTSDANTPDHWIARDERMIRLTGKHPFNSEAPLSELFSKGFLTPQNLFYVRSHGDTPRVTREQAENWKLKVHGLVEQEVELSIKDLKEKFPTVTLPITLVCAGNRRKEQNMVAKGLGFNWGAAGVSTGLFTGVYLADILDYCKPKNPLLSSFPSYDVAVPGRARHVVFEGADELPKGKYGTSQRLNWALDRCKGMLIAWGLNGEDLSPDHGYPLRLVVPGQIGGRMVKWLERIEVSDRESQHHLHFHDNKVLPTEVTADQARSEMHWWYDPKYIINDLNVNAAICSPDHDQVVNVAEPSTSSPQMLPLEGYAYTGGGRRIHRVEISLDDGHSWKCASIHYPEDLYRMYPIQGHEYFGTLDLSATEMSFSWCFWRLDVDVQADIIAKDVKVISVRALDEGLATMPRDMYWNATSMMNSWWFRVAVHREGENGNQIRFEHPTLAGNAPGGWMQRMNEAGLNPRYPQFGEAKAVESCKTDANTLAAAKEAKVDPKAIMIDPSKADTIITAADLAAHGDGEGPEPWFVVHGHVYDGTGFLKDHPGGDQSIRLVAGEDATEDFMAIHSMDAKKMLRDFHLGRLEKQDAAPPAATTEGEVLDLSKPFLDPKKWRATRLVSKQIISPDARIFRFALGSEDQELGLPVGQHVFVRVRSKNARTGETEMVQRAYTPYSGNTQRGFLDILIKVYFPSDAAATSAPAFEGGKMTMLLEKIDVSSPSDDLTIELKGPLGSFTYLGQQQIRWKPASAVRRVRKLAMIAGGSGITPIWSTLKAIADEVLDASNPSSPALDPIQIWIVYGNRTEQDILIREELERLRVALKGNLKVWHVLSNCTPENEANWSMGRGHITANVLRTHLPPPPAKPASEDELEDTLALVCGPPPMEKAVSDGLKQLGWDLQRCVVFF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADPH], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: RS6_BACC2
Sequence: MRKYEIMYIIRPGVEEEAQKALVERFAGVLTNNGAEIINTKEWGKRRLAYEINDLREGFYMILNVNSNAEAINEFDRLAKINEDILRHIVVKEEEK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RL13_RICBR
Sequence: MKTYSAKPSEIEKKWWVIDAKNVVLGRLASRVANMLRGKHKPSFTPHMDCGDNIIIINAEHVTLTGKKANPKDGKIYYRHTGFPGGIKDTTAGKILSGKHPERVIKMAVKRMITRNALGAKQMSNLYIYANSEHPHAGQQPVVYDFASQNPKNKK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: DBP5_NEOFI
Sequence: MASEQPVEAAPTGGSLADRITKPDESNTSETPAPAADQTDGAPAQLGGSDLHEPEYNVEVKLSDLQADPNNPLYSVKNFEDLGLDPRILKGLSNMNFRKPSKIQERALPLLLNNPPKNLVGQSQSGTGKTAAFVLNALSRVDLSTEQMQKTPQALILAPTRELARQILGVVQVMGQFVDGLIIGAAVPTDRDSRPKRLECSIVVGTPGTVGDMIKRRTFIPNKLKVLVLDEADNMLDQQGLGDQCIRVKALLPRDIQVVLFSATFPEHVHQYASKFAPNANEITLQHEELTVEGIKQLYLDCADGEDKYKTLVQLYGLLTVGSSIIFVQTRAAAQEIEKRMTAEGHTVVSLTGERDPSVRDAIIDQFRRGEAKVLIATNVLARGIDVSTVSMVINYDIPELHQPSVPGRQADFQTYLHRIGRTGRFGRVGVSISFVSNREEWEMLNQIQTYFNCEIQRVDTKDWDEVEDIIKKTIKNSRANPKFAGGKE
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: NATA1_ARATH
Sequence: MAPPTAAPEPNTVPETSPTGHRMFSRIRLATPTDVPFIHKLIHQMAVFERLTHLFVATESGLASTLFNSRPFQAVTVFLLEISPSPFPTTHDASSPDFTPFLETHKVDLPIEDPDREKFLPDKLNDVVVAGFVLFFPNYPSFLAKQGFYIEDIFMREPYRRKGFGKLLLTAVAKQAVKLGVGRVEWIVIDWNVNAINFYEQMGAQVFKEWRLCRLTGDALQAIDKLNI
What is the function of this protein?
Acetyltransferase that converts ornithine to N5-acetylornithine, which is likely used in plant defense.
What are the official names of this protein?
L-ornithine N5-acetyltransferase NATA1, Protein N-ACETYLTRANSFERASE ACTIVITY 1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: TX1B3_CAEEL
Sequence: MTAYGHMPGEAIECLSIAVELHKQEVIDAHGQVTIRVGFKIGGGIDQDPTKAPFKYPDSGVYITNVESGSPADVAGLRKHDKILQVNGADFTMMTHDRAVKFIKQSKVLHMLVARADLPPVSLH
What is the function of this protein?
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
What are the official names of this protein?
Tax1-binding protein 3 homolog.
Protein: DEF1_GALME
Sequence: MAKNFQSVLLLVCLSFLVIVSSPQNAVQADTLIGSCVWGATNYTSDCNAECKRRGYKGGHCGSFLNVNCWCE
What is the function of this protein?
Has antifungal activity against A. niger (MIC=2. 1 uM), C. albicans (MIC=8. 5 uM), C. fructus (MIC=8. 5 uM), F. oxysporum (MIC=16. 9 uM), P. pastoris (MIC=16. 9 uM), P. tannophilus (MIC=8. 5 uM), T. harzianum (MIC=4. 2 uM), and Z. marxianus (MIC=8. 5 uM).  Lacks antibacterial activity against the Gram-positive bacteria L. monocytogenes, M. luteus, S. aureus, and S. lutea, and the Gram-negative bacteria E. coli D31, E. coli ATCC 25922, and S. typhimurium.
What are the official names of this protein?
Defensin, Galiomicin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in the hemolymph.
Protein: LUTC_BACC2
Sequence: MTGLIQNRDAFLDNIAKELGRARKTEGVERPVWKSNVNIETLKDYSQEELLEVFKNQCTNIHTTVVETTNERLREDLQQVIMENGGGPILLSADERFDAYGLTSLFKEELPKRDVEVNVWDPERKDGNMRLAEKANIGIAFSDYTLAESGTIVVQSHKGQGRSLHFLPTVYLAIIPRETLVPRITQAVQDMNSRVEDGETAASCINFITGPSNSADIEMNLVVGVHGPLKAIYFIV
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein C.
What is the protein family that this protein belongs to?
Belongs to the LutC/YkgG family.
Protein: HBB_CICCI
Sequence: VHWTAEEKQLITGLWGKVNVDECGAEALARLLIVYPWTQRFFASFGNLATASAITGNAMVHAHGKKVLTSFGEAVKNLDNIKNTFAQLSELHCDKLHVDPENFKLLGDILIIVLAAHFGKDFTPDCQAAWKKLVRVVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CTPA2_ARATH
Sequence: MEVLASSSLSPISFTKPNKINPNFSIQVKLWVKQPPKISKASKFSYARSRSNISRSNAANPGVVFVCNRFLCVIERNDQRKLSGKVMMKSSVNFRQNLSVALVRIVSVLLVSSISVVTTDSPPSWGLTEENLLFLEAWRTIDRAYIDKTFNGQSWFRYRETALRNEPMNTREETYMAIKKMVATLDDPFTRFLEPGKFKSLRSGTQGAVTGVGLSIGYPTASDGPPAGLVVISAAPGGPANRAGILPGDVIQGIDNTTTETLTIYDAAQMLQGPEGSAVELAIRSGPETRLLTLTRERVSVNPVKSRLCELPGSGSNSPKIGYIKLTTFNQNASSAVREAIETLRGNNVNAFVLDLRDNSGGSFPEGIEIAKFWLDKGVIVYICDSRGVRDIYDTDGSNAIATSEPLAVLVNKGTASASEILAGALKDNKRALVYGEPTYGKGKIQSVFELSDGSGLAVTVARYETPAHTDIDKVGVTPDHPLPKSFPKDEEAFCGCLKDPTAACYLNQGLLFSR
What is the function of this protein?
Protease involved in the C-terminal processing of the chloroplastic D1 protein of photosystem II.  This proteolytic processing is necessary to allow the light-driven assembly of the tetranuclear manganese cluster, which is responsible for photosynthetic water oxidation.
What are the official names of this protein?
Carboxyl-terminal-processing peptidase 2, chloroplastic, D1 C-terminal processing protease 2, Photosystem II D1 protein processing peptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: SAR1_CHAGB
Sequence: MWIINWFYDVLSSLGLLNKHAKLLFLGLDNAGKTTLLHMLKNDRVAILQPTLHPTSEELSIGNVRFTTFDLGGHQQARRLWKDYFPEVNGVVFLVDAKDHERFPEAKAELDALLSMEELSKVPFVVLGNKIDHPDAVSEDELRHQLGMYQTTGKGKVPLEGIRPIEVFMCSVVMRQGYGDGIRWLSHFGN
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  SAR1 controls the coat assembly in a stepwise manner.  Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex.  These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase SAR1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SLMA_ECOK1
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYATDETLLASQILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LYSK_SULIM
Sequence: MQQEKELVKQKAKELLLDLLSIYTPSKNETNATKFFEKISNEFNLKLEILPDSNSFILGEGEILLASHVDTVPGYIEPKIENEVIYGRGAVDAKGPLISMIIAAWLLNEKGIKVMVSGLADEESTSIGAKELTLKNFNFKHIIVGEPSNGTDIVVEYRGSIQLDIMCESTPEHSSSAKSNLIVDISKKIIEVYKQPENYDKPSIVPTIIRAGESYNVTPAKLYLHFDVRYAINNKRDDLINEIKDKFQECGLKIVDETPPVKVSINNPVVKSLTRALLKQNIKPRLVRKAGTSDMNILQKITTSIATYGPGNSMLEHTNQEKITLDEIYIGVKTYMLAIEELWQKS
What is the function of this protein?
Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
What are the official names of this protein?
[LysW]-lysine/[LysW]-ornithine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. LysK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODAD1_RAT
Sequence: MRLGLSSRSARSEEGSEIFLEGPVDGELSRLHRQRKVMELERRAYSREVHQRIRKQVEEIRQLEMLRAKLQMQINVAQTQVKRLGDKKRLADMDHLLKCRAQVQIEIEALQEQNRALEKQIQDWETHILTQSKDISTPDVILDQKMKIQRRIRILEDQLDRVTCHFDIHLVRNAALREELELLRIERGRYLNMDRKLKKEIHLLQEMVGALSTSSTSAYTAREEAKTKMGMLQERAEKELAQSDTEAQILLRQISHLEQLHRFLKLKNHDRQPDPGVVQKEEQRAWETSEGLRKTSQEKLVLRYEDTLNKLAQLTGESDPDLLVEKYLELEERNFAEFNFINEQNSELYHLQEEIKEMQEALVSEHASQDKQSLEREQQCKVLQQDVEKVCSESERLEARFQVLRVQLEKIKTDIQVLFDKAQCDNSVIKDLLGVKTYMRDRDIGLFLSTIEKRLVQLLTVQAFLEVQNNVPLADAALLALGQSIQEPPKKTTPLKPPDTMEDSSGVVIKDDYPMSKEELLSQVMKLVQLQDEEGSPKKRDSSPSLTLSSPRISLAAASVHARKASVVPESILSHKTGRGRGTGSISHVTFGDSASAPGPVTLASTSASGLPVSGRGSQGGRGAFKHTSSSSYLGSTGYLETSRGRESGTGGGHSQSMGSEMSRGFSSGSGQTSSAAPASRPSSATSKDSRGYN
What is the function of this protein?
Component of the outer dynein arm-docking complex that mediates outer dynein arms (ODA) binding onto the doublet microtubule.  Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules (By similarity).
What are the official names of this protein?
Outer dynein arm-docking complex subunit 1, Coiled-coil domain-containing protein 114.
What is the protein family that this protein belongs to?
Belongs to the ODA1/DCC2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: SYT_XANCB
Sequence: MPMITITLPDGSRREFDAPVSVMQVAQSIGAGLAKATIAGQVDGQLVDASDLIEHDASLRIITAKDAEGVEIIRHSCAHLVGHAVKQLYPDVKMVIGPVIAEGFYYDIYSERPFTPEDMAAIEQRMQQLIAQDYDVIKKVTPRAEVIEVFAQRGEEYKLRLIEDMSDDITAMGLYYHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDAKNEQLQRIYGTAWADKKQLDAYILRMEEADKRDHRKIGKAQDLFHLQEEAPGLVFWHPKGWSLWQVVEQYMRKVYRDSGYGEVRCPQILDVSLWQKSGHWDNYQDAMFFTESEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGILRVRGFTQDDGHVFCLESQIEAEVTAFHQQALAVYTAFGFDDIQIKIALRPEKRLGDDATWDKAEAALRSALGVCGVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTMQVDFMMPGRLGAEYVDEHSQKKHPVMLHRAIVGSMERFIGILIEHHAGAFPAWLAPVQVVVANITDAQAEYVDSVRKTLANQGFRVSADLRNEKIGYKIREHTLQRVPYLLVVGDREKENGAVAVRTRSGEDLGTMTVSAFIERLQAEQAA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDAR_HUMAN
Sequence: MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS
What is the function of this protein?
Receptor for EDA isoform A1, but not for EDA isoform A2.  Mediates the activation of NF-kappa-B and JNK.  May promote caspase-independent cell death.
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member EDAR, Anhidrotic ectodysplasin receptor 1, Downless homolog, EDA-A1 receptor, Ectodermal dysplasia receptor, Ectodysplasin-A receptor.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: OADG_VIBVU
Sequence: MTNIGSLLVDAAALMVTGMGVVFIFLTILIFLVRLMSKLVPQEVPPPITAPKAVKNQANHTSTVSPQVVAAISAAIHQHRASVAK
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
What are the official names of this protein?
Probable oxaloacetate decarboxylase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the OadG family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.