PharMolix/UniProtQA huggingface dataset:
Protein: MEND_SHEWM
Sequence: MQIEKTAELNLLWGTLILEELSRLGVQHICMAPGSRSTPLTLAAAKQSKLKQHLHFDERGLGFMALGLAKASQAPVAVVTTSGTAVANLYPAVIEAWLTHVPLIVLSGDRPPELIDCGANQAIIQPAIFAQYAKQINLSTPDLAIRPEALLTLLDEAISNQSQPLHINCMYREPLYPSTMSANFTQYLSTLGNWQHTNHAYNQYGKPNLSSLPSSDAMARFVHGKGVIIAGTLTPDCDPQALVALSQKLGWPLLTDAQSQLRQHPGVIGNIDQLLHQPKAKALLMQAERVLVIGGRLLSKRLIDYLAQNKWKSYWQVLPRQMRLDPSHSAKQIWHASVTNITSLSWPRSSEANWALQLTQQNDEMERLFEQQIDNAEFGEAMVVRAIAKSQTKQQQLFIGNSLPVRLYDMFAPITTEQGATFTNRGASGIDGLLASACGVAMHQGRATTLIIGDISQLHDLNSLAIASHCSSPLVIVILNNDGGNIFNLLPVPDEKLRSDYYRLAHGFEFGYGAAMFGIPYNRVEELESFEESYQDAIHYEGASVIEVIVPQQQASDQIARIASWIKQS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RPOY_STRMU
Sequence: MIYKVFYQETKDSSPRREQTKTLYLDIDAQTELDGRIQARQLVEEKIAYNIELIELLSDKHLEYEKETGAFQLTEF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: THSA_THEK1
Sequence: MAQLSGQPVVILPEGTQRYVGRDAQRLNILAARIIAETVRTTLGPKGMDKMLVDSLGDIVVTNDGATILDKIDLQHPAAKMMVEVAKTQDKEAGDGTTTAVVIAGELLRKAEELLDQNIHPSIIIKGYALAAEKAQEILDEIAIRVDPDDEETLLKIAATSITGKNAESHKELLAKLAVEAVKQVAEKKDGKYVVDLDNIKFEKKAGEGVEESELVRGVVIDKEVVHPRMPKRVENAKIALINEALEVKKTETDAKINITSPDQLMSFLEQEEKMLKDMVDHIAQTGANVVFVQKGIDDLAQHYLAKYGIMAVRRVKKSDMEKLAKATGAKIVTNVKDLTPEDLGYAEVVEERKLAGENMIFVEGCKNPKAVTILIRGGTEHVIDEVERALEDAVKVVKDVMEDGAVLPAGGAPEIELAIRLDEYAKQVGGKEALAIENFADALKIIPKTLAENAGLDTVEMLVKVISEHKNRGLGIGIDVFEGKPADMLEKGIIEPLRVKKQAIKSASEAAIMILRIDDVIAAKATKPEGGQGGGMPGGMGGMDMGM
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit alpha, Chaperonin subunit alpha, Thermosome subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: NUOJ_BUCBP
Sequence: MEFFFYSSSLATIVFTVCSIFSRNLMYSLLYLILSFVFTSCVFFSLGATFAAALEVIIYAGAIMVLFVFFIMMFNFKKSTLYAEKIFDKNNYYYINFLFLLCILIFPFFFILSYLYKEKIFYMVVSTKLVAIKLFSDYILVIELSSIVLLSALIIVSHIGKIRR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit J, NADH dehydrogenase I subunit J, NDH-1 subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL7_RHOP2
Sequence: MADLQKIVDDLSSLTVLEAAELAKLLEEKWGVSAAAAVAVAAAPGAAAAAVEEKTEFTVMLAAAGDKKIEVIKEVRAITGLGLKEAKDLVEGAPKPVKEGVNKEEADKLKAQLEKAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: BIOB_ANAMF
Sequence: MIRNNWTLEEALELFRMPFSDLILKAHSVHVQNFRNNEVQVAALMNIKTGSCPENCRYCAQSAHYNTGLEKKSLSTVEEVKTAAKRAKEIGADRFCFAAAWRNLHDRDLEKICQFVEAIKSEGLESCASLGMLKLDQAQKLKESGLDFYNHNVDTSREFYHNVVTTRTYEERLETVRNVQQAGIKVCCGGILGMGESTEDRASMLVTLANLEQHPLSVPINRLVPIEGTPMEGNPKIDNIDFVRTIAVARIMMPASYVRLAAGRGEMSEEMQALCMLAGANSIFCGEKLLTTPNARPEDDQRLFSQLGITPSRAACTTSDAQLA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: DCUP_PELPD
Sequence: MNTRFLDACWGKPVDRVPVWLMRQAGRYLPEYMAVRSRCTFLELCKTPELAAQVSLQPVDILGVDAAILFSDILTPVEPMGMKLDFVPGPVFEKPVRCMADVERLRIPRMEDDLPFVFDIIRILRRELADRVPLIGFGGAPFTLACYMVEGKGSKDFVQIKRMMYSAPDVYAALMEKITTMSMEYLNAQIAAGAQAIQIFDTWGGILSPSDYRTHVLPHTTRLINGLNRLTTPVIHFVKGAGTMLETVREAGGDVIGLDWHVDLATARNQLGPGVAVQGNLDPTVLFAPQAVIEQQVQRVLDENRGLPGFIFNLGHGILPTVPAENARFMVQCVQRLSRS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP5G_CLOBA
Sequence: MQITDVRIRKISSEGKMKAIVSVTFDNEFVVHDIKVIEGQNGLFIAMPSRKTPTGEFKDIAHPIVMDSREKIQNEILSAYAKAIEEQDVEE
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: MFNB_METMA
Sequence: MKLLVSPINSEEAIIASIGGADIVDVKNPKEGSLGANFPWVIREVKAVVNGRQPISATIGDFNYKPGTAALAALGAAVAGADYIKVGLYDIQTESQALELLTKITRAVKDYNPLKKVVASGYSDYKRINSISPLLLPAVAAEAGVDVVMVDTGVKDGKSTFEFMDEKELKEFTDLAHSYGLENAIAGSLKFEDIPLLERIGPDIIGVRGMVCGGDRSTSIRQELVEKLVAECQA
What is the function of this protein?
Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
What are the official names of this protein?
(5-formylfuran-3-yl)methyl phosphate synthase, 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase, 4-HFC-P synthase.
What is the protein family that this protein belongs to?
Belongs to the MfnB family.
Protein: NQRB_VIBAL
Sequence: MALKKFLEDIEHHFEPGGKHEKWFALYEAVATVFYTPGIVTNKSSHVRDSVDLKRIMIMVWFAVFPAMFWGMYNAGGQAIAALNHMYAGDQLATVISGNWHYWLTEMLGGTIAADAGVGSKMLLGATYFLPIYATVFLVGGFWEVLFCMVRKHEVNEGFFVTSILFALIVPPTLPLWQAALGITFGVVVAKEIFGGTGRNFLNPALAGRAFLFFAYPAQISGDVVWTAADGFSGATALSQWAQGGNGALVNTVTGSPITWMDAFIGNIPGSIGEVSTLALMIGAAMIVYMRIASWRIIAGVMIGMIAVSTLFNVIGSDTNPMFNMPWHWHLVLGGFAFGMFFMATDPVSASFTNKGKWWYGILIGAMCVMIRVVNPAYPEGMMLAILFANLFAPLFDHVVIEKNIKRRLARYGK
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-NQR subunit B, Na(+)-translocating NQR subunit B, NQR complex subunit B, NQR-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDI23_ORYSJ
Sequence: MRPAVAAALLLVAAAVAASPVSALYSAGSPVLQFNPNNFKSKVLNSNGVVLVEFFAPWCGHCQQLTPIWEKAAGVLKGVATVAALDADAHKELAQEYGIRGFPTIKVFVPGKPPVDYQGARDVKPIVEFALSQVKALLRDRLNGKTSAGSGGKKSGGSSEKTEPSASIELNSQNFDKLVTKSKDLWIVEFFAPWCGHCKKLAPEWKKAAKNLKGQVKLGHVDCDAEKSLMSKYKVEGFPTILVFGADKESPFPYQGARVASAIESFALEQLEANAAPPEVSELTGPDAMEEKCASAAICFVSFLPDILDSKAEGRNKYLELLLSVAEKFKKSPYSFVWTAAGKQADLEKQVGVGGYGYPAMVALNVKKGAYAPLRSAFQLDEITEFVKEAGRGGKGNLPLDGTPTIVQSEPWDGKDGEVIEEDEFSLEELMADNSPVNDEL
What is the function of this protein?
Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.  May play a role in storage protein biogenesis.
What are the official names of this protein?
Protein disulfide isomerase-like 2-3, OsPDIL2-3, Protein disulfide isomerase-like 5-1, OsPDIL5-1.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Note=Localizes on the surface of ER- derived type-I protein bodies in the endosperm.
Protein: CRVP_SISCA
Sequence: MIALIVLPILAAVLQQSSGSVDFDSESPRKPEIQNKIVDLHNSLRRSVNPTASNMLKMEWYSEAAANAERWAYRCIESHSPRDSRVLEGIKCGENIYMSSVPMKWTEIIHIWHGENKNFKYGIGADPPNAVTGHYTQIVWYKSYRAGCAAAYCPSLEYSYFYVCQYCPAGNIRGKTATPYKSGPPCGDCPSACDNGLCTNPCPKKISTQLPRFGPQAGCQDKQMQSDCSATCFCQNKII
What is the function of this protein?
Weakly blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein 2, CRVP, Cysteine-rich secretory protein 2, CRISP-2.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: RDRP_I72A4
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRVNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITKNQPEWFRNILSIAPIMFSNKMARLGKGYMFESKRMKLRTQIPAEMLASIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARVDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: Y096_GVCL
Sequence: MSSTDMAVLLLVIALIFLIVNTLDNPLIMIGTRLIESTRVKVGPFIHVLERDGDRLFVIEPEQTLLYNTAGLIYYYFEGGASRRFCPVGEQAIVRIGLTDIGLINENGIYNVSCTNTSSWDLYEHFKNDSFEWKLPTFYEKTSIIDIINELIRYGYVRIGYQ
What are the official names of this protein?
Uncharacterized 18.6 kDa protein in P143-LEF5 intergenic region.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae 19 kDa protein family.
Protein: DLP2_ORNAN
Sequence: MRLAYLLLLLVAVLFQAGGGSAKPIMFFEMQACWSHSGVCRDKSERNCKPMAWTYCENRNQKCCEY
What is the function of this protein?
Does not show antimicrobial, myotoxic, hemolytic and cell-promoting activities.
What are the official names of this protein?
Defensin-like peptide 2/4, DLP-2/DLP-4, Ornithorhynchus venom defensin-like peptide B, OvDLP-B.
What are the subcellular locations of this protein?
Secreted.
Protein: MEND_SYNR3
Sequence: MSIEAAENLRAAEALLSALMGLGLQRVVLCPGSRSGPLALAASRLESHGLALTTGIDERSAGFFALGQTRADGQPTAVITTSGTAVANLLPAAVEADFSALPLLLLTADRPERLKACGANQTVNQEAYLQPACRALLQGPAAGLHDASDERLLRLAQSAMRHALGAPAGPVHLNLAFDEPLHADLSGLPAAAPPAAQELPPLFEPPGLGSLEPLDPDQPGVIVVGPWRRGHGGRFVAALQQLNRRTGWPILADASSGLRGLPLPLVSGYDLLLAEPQRLPPAHQVLRLGSMPASRRLQQWLQTFEGPQLVITEAEPRRQDPLASGCAQHPHGLAAWVELLPTGEPSATSRADAARWQQAESLLQQQLDHDLPLQGPCSEPALARALQNLIPSEWPVMLASSSPVRDWESFAGRQSGHRTIVSFRGASGIDGTLSLAAGIAQQWQRLVLVTGDLALLHDANGWLWRRQLSGELRLVVIDNGGGGVFEQLPIPRQSMDFDRLFAMPQSCDAMALAAAHGVAARDCSAMETLAADLQWLLEPGDAMRLLRCSTDRSRDAQLRQQLRDKPWWEQTPAP
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: CLPS_SALPK
Sequence: MGKTNDWLDFDQLVEDSVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: EFTU_GEOSL
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLAERGQAEFRGFDQIDNAPEERERGITIATSHVEYETEKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIVVFLNKADMVDDEELLELVELEIRELLSSYDFPGDDIPIIKGSALKGLNGDKDELGEEAILKLMEAVDNYIPEPERAVDKPFLMPVEDVFSISGRGTVATGRVERGIVKVGEEVEIVGIKATAKTTVTGVEMFRKLLDEGRAGDNIGALLRGVKREDIERGQVLAKPGSITPHTKFKAEAYILTKEEGGRHTPFFNGYRPQFYFRTTDVTGVVDLPAGTEMVMPGDNVAVTINLITPIAMDEGLRFAIREGGRTVGAGVVSSIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDGR3_RAT
Sequence: MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQTIQQQSSSETEGEGGNTADASSEEEGDRVEDGKGKRKNEKGGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKAGEGT
What is the function of this protein?
Enhances DNA synthesis and may play a role in cell proliferation.
What are the official names of this protein?
Hepatoma-derived growth factor-related protein 3, HRP-3.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYP_STRT1
Sequence: MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYMPLANRAIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKSDFILGPTHEETFTVLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDAYSFHQNYEDLDVTYEDYRKAYEAIFTRAGLEFKAIIGDGGAMGGKDSQEFMAVTPERTDLNRWVVLDKSIASLDEIPEDVMEEIKNELTSWLVAGEDTIAYSTESSYAANLEMATNAYTPATKVVTQEEVSRVETPGCKSIDDVAAFLNIPEEQTIKTLLFTADDEPVVALLVGNDQVNDVKLKNYLAADFLKPATEDEARQVFGANFGSLGPVNLPENVRIIADRKVQDVANAVVGANEDGYHLTGVNPERDFKAEYVDIRKVKEGEISPDGQGVLQFARGIEIGHIFKLGTRYSESMGANVLDENGRAVPIIMGCYGIGVSRILSAVIEQHARLFVNKTPKGQYRYAWGINFPKELAPYDVHLITVNTKDEEANALTDRLEAALAAEGYDVLIDDRNERVGSKFSDSDLIGLPIRVTVGKKASEGVVEVKIKATGDTIEVNADNLIETLAILTTEQDA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS1_CANAL
Sequence: MVQGKVLVVSNRIPVTIKRLDNGSYDYSMSSGGLVTALQGLKKTTEFQWYGWPGLEIPEDEQTKVNDELKSKFNCTAIFLSDTIADLHYNGFSNSILWPLFHYHPGEMNFDENAWAAYIEANKKFALEIVKQVNDDDMIWVHDYHLMLLPEMLRQEIGNKKKNIKIGFFLHTPFPSSEIYRILPVRKEILEGVLSCDLIGFHTYDYARHFISSVSRIVPNVSTLPNGIKYQGRSISIGAFPIGIDVDNFIDGLKKDSVVERIKQLKSKFKDVKVIVGVDRLDYIKGVPQKLHAFEVFLNENPEWIGKVVLVQVAVPSRGDVEEYQSLRSTVSELVGRINGEFGTVEFVPIHYLHKSIPFDELISLYNISDVCLVSSTRDGMNLVSYEYIACQQDRKGVLILSEFAGAAQSLNGALIVNPWNTEDLSEAIKESLTLPEEKREFNFKKLFTYISKYTSGFWGESFVKELYKCNPQKSLRD
What is the function of this protein?
Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process.
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Trehalose-6-phosphate synthase, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: NDUA8_DICDI
Sequence: MESFTRAELVAQRDGVWAVCGEVFEAYEKCRMEKGSDPELCLRESTAVVGCSQKVMREIVKNCQKELNESVKCIEENNMRTIPCEEENKAFNECFDKLVAPKFL
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA8 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
Protein: PNP_STRT1
Sequence: MAKQTFEMTFEGRPLVVEVGQVAKQANGAVVVRYGDTTVLSVAVMSKKMATANFFPLQVNYEEKMYAAGKFPGGFSKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVAYAAEDFIINPSASDKEVSHLDLIVAGTKEAINMVEAGAQELSEDIMLQALLKGHEAIQELVDFQNYIVAAVGKEKAEVELFQVDADLKAEIEAVYYDQLAKAVQVEEKLAREAATKAVKEEVLASYQERFAEDEDKETILRDVVEILEQMEHAEVRRLITEDKIRPDGRRVDEIRPLDAEIDFLPNVHGSGLFTRGQTQALSVLTLAPMSDTQLVDGLDPEYKKRFLHHYNFPQYSVGETGRYGAPGRREIGHGALGERALAQVLPSVEEFPYAIRLVAEVLESNGSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRLGITALQMDIKISGITPAILEEALAQAKVARFEILDVIESAIAEPRSELAPTAPKIDSIQIPVDKIKVVIGKGGETIDKIIAETGVTIDIDEEGLVQIFSSDQDAIDRAKTIISDLVREAKVGEVYTVPVVRIEKFGAFVHLFNKTDALVHISELAWKHTEHVEDVVKVGDMVTVKIIKIDEKGRVDASIKTLLPKPEKNEDGENGEEHRHCCCSHHKPDHHNESVEAPKKSDESETKE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_VIBPA
Sequence: MALWGGRFTQAADTRFKEFNDSLRFDYRLAEQDIVGSIAWSKALLSVGVLSAEEQQKLELALNELKLEVMEDPHQILRSDAEDIHSWVEQQLISKVGDLGKKLHTGRSRNDQVATDLKLWCRQQGQQLLIALDRLQSQMVQVAKQHQGTVLPGYTHLQRAQPVTFAHWCLAYVEMFERDYSRLSDALQRLDTCPLGSGALAGTAYPIDREQLAHNLGFHRATRNSLDSVSDRDHVMELMSVASISMLHLSRLAEDMIFYNSGESNFIELADTVTSGSSLMPQKKNPDALELIRGKTGRVYGALAGMMMTVKALPLAYNKDMQEDKEGLFDALDTWNDCMEMAALCFDGIKVNGERTLEAAKQGYANATELADYLVAKGIPFREAHHIVGVAVVGAIAKGCALEELSLQELQEFSDVIDNDVYDILTIESCLEKRSALGGVSPKQVAYAVDQADKRLAQRDSSAVKVRPARLTDIETLEGMVAYWANMGENLPRSRNELVRDIGSFAVAEHHGEVTGCASLYVYDSGLAEIRSLGIEAGWQGQGQGSAIVNYLVDKARQMAIKKVFVLTRTPEFFMKQSFLPTSKSLLPEKVLKDCDQCPRQHACDEVALEINLVEQIIQRSHVA
What are the official names of this protein?
Bifunctional protein ArgH.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTM1_HUMAN
Sequence: MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911).  Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276).
What are the official names of this protein?
Glutathione S-transferase Mu 1, GST HB subunit 4, GST class-mu 1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBBA4_HYAOR
Sequence: WPPVEGRPSCKRCGACTRMWPPEANRCVCDDIVPQCHEGCSKCEKVDTRSGKPLYQCQSFEYYNCAA
What is the function of this protein?
Serine protease inhibitor (PubMed:33666645).  Inhibits trypsin (Ki=12nM) and weakly inhibits chymotrypsin with (Ki=460nm) (PubMed:33666645).  Does not inhibit bacterial subtilisin (PubMed:33666645).
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor A4, HOSPI-A4.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: LEUE_SALCH
Sequence: MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVGRGVKGGYLAACGVFIGDAILMFLAYAGVATLIKTTPVLFNIVRYLGAFYLLYLGAKILYATLTSKGRAATETVVPFGAIFKRALILSLTNPKAILFYVSFFVQFIDVTAPHTGVSFFILATTLEIVSFCYLSFLILSGAFVTHYIGTKKKLAKVGNSLIGLLFVGFAARLATLQS
What is the function of this protein?
Exporter of leucine.
What are the official names of this protein?
Leucine efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NEU1_STRCA
Sequence: AVLDMDIRKCMPCGPRNKGHCFGPNICCGEELGCYFGTSETLRCQEENFLPTPCESGRKPCGNNEGSCAASGICCSNEGCMVDSSCDQEVMFP
What is the function of this protein?
Neurophysin 1 specifically binds oxytocin.
What are the official names of this protein?
Neurophysin 1.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
Protein: FENR_STRPN
Sequence: MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPAILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSKGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAVDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKLEITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAIGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.