PharMolix/UniProtQA huggingface dataset:
Protein: RR14_ARATH
Sequence: MAKKSLIYREKKRQKLEKKYHLIRRSLKKEISKIPSLSEKWKIHGKLQSLPRNSAPTRLHRRCFSTGRPRANYRDFGLSGHILREMVQACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LEPA_ECO55
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVRCSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLRKGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTLARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPAVNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRGRELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL10A_XENLA
Sequence: MSSKVSRDTLYEAVREVLQGSKKKKRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSLCVLGDQQHCDEAKAVDLPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENLVAKVDEVKSTIKFQMKKVLCLAVAVGHVKLTEEELVYNIHLSINFLVSLLKKNWQNVRALYIKSTMGKPQRLY
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L10a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_GEODF
Sequence: MVHPFLFLQFFRHLLTPLGISEGGADAIAYTWLIIALLLIVSILATKGLKSVPGKMQNFMEVIIGGIENMVVETMGEHGKPFFPLIATLALFILVSNLIGLIPGFFPPTANINTTAACAVIVFVTTHIVGIKEHGVKYIKHFLGPILWLAPMMFFIEVIGHFSRVISLTLRLFGNMNGHELVLMIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLAMIYIQGSLEEGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEPT_PARD8
Sequence: MTVLDRFLKYVTFDTQSNEETGTTPSTPGQRVFAEALVKELEAIGMEEISLDENSYVMATLPANTDEKIPTIGFIAHLDTSPDMSGKNVQPRIVTYLGGDIVLDAEENVVLSQSMFPELSDYKGQDIIVTNGKTLLGADDKGGVAAIVASMQYLKDHPEIKHGKIRIAFTPDEEIGQGADHFDVEKFGCDWGYTIDGGQIGELEYENFNAAGAKIIFKGLNVHPGYAKDKMQNASLRAIEFASWLPAEQRPEHTTGYEGFFHLTGMTGSVEEATLSYIIRDHDRKLFEEKKELLRTLVDKMNEAHPGCAHLELRDQYYNMREVVEPQKHIVDLAFEAMTSVGVEPIVKPIRGGTDGARLSFMGLPCPNIFAGGLNFHGRYEFLPVRSLEKSMETVIKIIELSARKS
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPOA_PECPW
Sequence: MLPFHLVRTQAGRVIPVLLAALFLAGCPSHAPQSPPPEVQGKADASSDYYLQQMQQSSDNNKADWQLLAIRSLLQEGKAPQASQQFNTLPEKLSAAQKQEQQLLSAELSAAQNNMDAAKAALSQLDVGALSEQQKSRYYQTQIKTAQGRPSIELLRAYIAQEPLLKGDEHQMNLDQTWLALTQMSPQESGALLINADENVLQGWVDLLNNYQNNRESPDQLQSAIQDWKTRYPHHPAAKNLPMQLNQVINYQPSSVSSIALLLPLNGQAQVFANAIQQGFNAAKNGQIATAAVSAPVAPPTDTAQAGQVTPSSDGQNAQSPAPYSDQAVASTTPAPAAQATSAGLSSSLPVKVYDTSSQPLANILTQAQQDGASLVIGPLLKNEVDQLASNPSPLNILALNQPERVENSPNICYFALSPEDEARDAAKFIHQQGKQQPLVLAPRGALGDRIVNAFAQAWNQQSGTSALQQRFGNSAELKQAINSGAGLSLNGQPVNVSQQQAQAGTTIGGLTIPSQVQPTASSSVSGNIDAVYIIATPDELALIKPMIDMRTSSRARPALYASSRSFQAGLGPDFRLEMEGLQFSDIPLLAGANPALMQQVSSQFKNDYSLVRLYAMGMDAWTLASHFGEMRQIPGHQISGATGMLSAGPDCTINRQLTWQQYRQGQLVPVL
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: PDR12_YEAST
Sequence: MSSTDEHIEKDISSRSNHDDDYANSVQSYAASEGQVDNEDLAATSQLSRHLSNILSNEEGIERLESMARVISHKTKKEMDSFEINDLDFDLRSLLHYLRSRQLEQGIEPGDSGIAFKNLTAVGVDASAAYGPSVEEMFRNIASIPAHLISKFTKKSDVPLRNIIQNCTGVVESGEMLFVVGRPGAGCSTFLKCLSGETSELVDVQGEFSYDGLDQSEMMSKYKGYVIYCPELDFHFPKITVKETIDFALKCKTPRVRIDKMTRKQYVDNIRDMWCTVFGLRHTYATKVGNDFVRGVSGGERKRVSLVEAQAMNASIYSWDNATRGLDASTALEFAQAIRTATNMVNNSAIVAIYQAGENIYELFDKTTVLYNGRQIYFGPADKAVGYFQRMGWVKPNRMTSAEFLTSVTVDFENRTLDIKPGYEDKVPKSSSEFEEYWLNSEDYQELLRTYDDYQSRHPVNETRDRLDVAKKQRLQQGQRENSQYVVNYWTQVYYCMIRGFQRVKGDSTYTKVYLSSFLIKALIIGSMFHKIDDKSQSTTAGAYSRGGMLFYVLLFASVTSLAEIGNSFSSRPVIVKHKSYSMYHLSAESLQEIITEFPTKFVAIVILCLITYWIPFMKYEAGAFFQYILYLLTVQQCTSFIFKFVATMSKSGVDAHAVGGLWVLMLCVYAGFVLPIGEMHHWIRWLHFINPLTYAFESLVSTEFHHREMLCSALVPSGPGYEGISIANQVCDAAGAVKGNLYVSGDSYILHQYHFAYKHAWRNWGVNIVWTFGYIVFNVILSEYLKPVEGGGDLLLYKRGHMPELGTENADARTASREEMMEALNGPNVDLEKVIAEKDVFTWNHLDYTIPYDGATRKLLSDVFGYVKPGKMTALMGESGAGKTTLLNVLAQRINMGVITGDMLVNAKPLPASFNRSCGYVAQADNHMAELSVRESLRFAAELRQQSSVPLEEKYEYVEKIITLLGMQNYAEALVGKTGRGLNVEQRKKLSIGVELVAKPSLLLFLDEPTSGLDSQSAWSIVQFMRALADSGQSILCTIHQPSATLFEQFDRLLLLKKGGKMVYFGDIGPNSETLLKYFERQSGMKCGVSENPAEYILNCIGAGATASVNSDWHDLWLASPECAAARAEVEELHRTLPGRAVNDDPELATRFAASYMTQIKCVLRRTALQFWRSPVYIRAKFFECVACALFVGLSYVGVNHSVGGAIEAFSSIFMLLLIALAMINQLHVFAYDSRELYEVREAASNTFHWSVLLLCHAAVENFWSTLCQFMCFICYYWPAQFSGRASHAGFFFFFYVLIFPLYFVTYGLWILYMSPDVPSASMINSNLFAAMLLFCGILQPREKMPAFWRRLMYNVSPFTYVVQALVTPLVHNKKVVCNPHEYNIMDPPSGKTCGEFLSTYMDNNTGYLVNPTATENCQYCPYTVQDQVVAKYNVKWDHRWRNFGFMWAYICFNIAAMLICYYVVRVKVWSLKSVLNFKKWFNGPRKERHEKDTNIFQTVPGDENKITKK
What is the function of this protein?
Plasma membrane transporter which mediates resistance to water-soluble, monocarboxylic acids with chain lengths of from C1 to C7 by active extrusion of the preservative anions from the cytosol.  Also involved in the export of aromatic and branched-chain organic acids produced in amino acid catabolism.
What are the official names of this protein?
ATP-dependent permease PDR12.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMD_LACDA
Sequence: MNINVLTLFPEMFTPLQVSLLGRGQEDGKWKLNLVNFRDFSDRPHKSVDDTPYGGGAGMVLQVKPIKDALDSLENKGKVIITAPQGKTFNEQMAQEWSKEENLTFICGHFEGFDQRVYDLADEMVSIGDYVLTGGELPTMSMIDATVRLLPGILGNALSTVEESFSDGLLEYPQYTRPADFEGQKVPEVLLSGNHGKIDEWRHYQALKATKLHRPDLLEKRDLTPEEVRMLRQIREDEQAEEDKL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MODC_BORPE
Sequence: MPSDFPPGQAGIHARFRVDYPEFSLDVDLRLPGRGVTALFGQSGSGKTTCLRCMAGLAPVSDGYLDINGEVWLDSAARRAVPTHKRALGYVFQEASLFEHLDVLANLRYGMKRVPPALRRVDLEQATGLLGIGHLLARMPAGLSGGERQRVGIARALLTSPRLLLMDEPLAALDVQRKREILPYLERLHDELDIPVIYVSHSPDEVARLADHLVLLEQGRAVASGPLDALLTRLDLPMAMTDDASVVVTGEAAGFDPGYALLTLQLPGGRARLRFVHQAAPAGQRLRVVVHARDVSLALQQPREGSILNVLAVRVLEMAPAANPAHVMVRLDADGTPLLARITRYSRDRLALAPEMQAWAQIKAVSLLA
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DDDD_MARMS
Sequence: MNKQNQLPLVGVRVADFGQQIAGPAVAMVLADLGATVVHIDPPGGPSWKHPANAILNRNKASLCIDLKTQAGLDQALELIENVDIVIESFRPGVMKRLGIDFVALRESRPELITLSMPGFASNDELHRDWKATEAIVAATSGTFTDMGFNRVLMGLNPSFSPLPLGSSYAISLAASSIALALFEREKTGRGDNIEVPIAAALMEGLSYNSYVVDQLPERYKTMRELEIEHRKSNNIKMDVSYAQLQEYLDPFYRTYVCADGRQFYCVCPSHRNHAERALKVLGIYDELVAEGLPEVKDLHVPISEWDGETSIGVYPLPKKWADLISEKMKKAFLQKTSDEWGVIFGEGQIPGAPHRSTEEWVNSEHCNASGLIVEVEGTEFGTMKQPGPIVWFENESEAMLKPKPQEHVSFEQALARLQSVAKIEKISRPTGQDIQPASGKGWLDGVKILDLTNVIAGPHSTAFMSRFGAEITKLDPVTPLYDPLIGILFTFQTGVGKQSALVNIMTKEGREVFERLVRSVDIVVINAPDRQMKPLGLDQDSLSAINPDVLFCRLDCFGGPRTGSKTNYIGYDDIIQANSGIMSRFGKPETPEEHAHLGTLDVNCGFAAALGMVIALYQKRKTGKVCRVRTSLSAVTNIAQIPFAFDYEGRAPFNEASGREAMGNHALSHFYRTNSGWVFLDSHQGELAKLDAIKGLNGIQQSQDMGQFLRDQLVKESSAYWLKEFAAADIACAEPFSIEYLREHNSRVADQKVGTDLGSYAFSIFPDHPSGHCITQVDPYSIRPREAKIRAVTPTEKFGCSTIKVLQGLGYSESDINDMLEKKIAATGWGREFLPS
What is the function of this protein?
Dimethyl sulfide (DMS)-producing enzyme (PubMed:17272727, PubMed:25140443).  Acts both as a transferase and a lyase: uses acetyl-coenzyme A (acetyl-coA) and dimethylsulfonioproprionate (DMSP) as substrates to produce DMS, acetate and 3-hydroxypropionate-CoA (3HP-CoA).  Mediates the CoA-transferase prior to lyase activity (PubMed:25140443).  DMS is the principal form by which sulfur is transported from oceans to the atmosphere and is a key component of the ocean sulfur cycle (PubMed:17272727, PubMed:25140443).
What are the official names of this protein?
CoA-transferase/lyase DddD.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family.
Protein: PIRL1_ORYSJ
Sequence: MREMGEKRRRGHLNPAGFAGGLHDHEEKKNEEHKLDMSGMSMDALPHLTMSLGQVTILDLSNNNLESIPESIIARLLNVVVLDVRSNQLKSLPNSIGCLSKLKVLNVSGNLLESLPNTIEECRALEELHANFNELTKLPDTLGFELHSLRKLSVNSNKLAQLPSSTSHMTALRALDARLNCLRALPDGLENLANLEALNVSQNFQFLRELPYAVGLLASLRELDVSYNSIAALPDSMGCLTKLARFSAVGNPLVSPPMDVVEQGLDAMRAYLTARMNGGDGKRKKKAWLPKLVKYSTFTARMTPGRTRVHENTEGLLMSDYRSLNGIASPRFLTMLSPRRLFSPRRNSPKHC
What is the function of this protein?
Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction.
What are the official names of this protein?
Plant intracellular Ras-group-related LRR protein 1, Intracellular Ras-group-related LRR protein 1, OsIRL1.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
Protein: RPOC1_PLAF7
Sequence: MIIHNNINFIGLKLNILNPKQIIKWSSIFYKNKIIIGEVLIPNTINFNTGLPILNGLFCEKIFDYMYKWNCNCNKKMYNINNFSFFLYCKFCKNKLIININRKYKLGFIFLNIPILHLWYLTGPLKVASLLLNKNVFYLKFLIYYKYFFSNIKYKQYFYYNKLFSKINLYKKKYKNIIQYLFSHNILYKKLQNINLLTELLNNKELLLINNKYYNKKYLYKKINLFNLFILNNIKPNWIFLDLLPILPAGLRPYFYINNSTYIISTINENYRLIILKNNKLKYWLYLRNNIFFIFEIIEKRLLQQLIDYLLINKLILKNNNTFFNFSKTFQGKYSTIKYKLLGKRVDFSGRSVITVNPSIIYNNIGLPYYISINLFKPFLINILKYNSKLNIIFKSLLINKNLFIIQKFLNRLLQNQFIIINRAPTLHRMNLQSFKPLLTEGYSLKFYPLGCTSFNADFDGDQMSIFLPLIKTSKFESNINLNFDKNIISPSNNKNLFSNLQYYKLGINTLLILNYNNELNIFYFNSIEKIYEYYNNNILFIFNLVWIKYINNNNIFYILTSINRIIINLYMYIY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Plastid, apicoplast.
Protein: RL1_ACIBT
Sequence: MAKLTKRQKAIAAAVEANKVYTLEEAVQVLNSLPAAKFKESLDISVNLGVDPRKSDQVVRGATTLPAGTGKTVRVAVFAQGAQAEAAKEAGADVVGFDDLAESIQGGNLDFDVVIAAPDAMRVVGKLGTILGPRGLMPNPKVGTVTPDVAGAVKNAKSGQARYRVDKAGIIHAAIGQVGFDAAAIRQNVETLVADLKKLKPATSKGVYIKKITLSSTMGPGLTVDVNNVSN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ATPB1_VIBC1
Sequence: MATGKIVQIIGAVVDVEFPQSEVPSVYDALNVTDSKERLVLEVQQQLGGGVVRCIVMGSSDGLRRGVEVVNTGAPISVPVGTKTLGRIMNVLGDAIDERGEIGAEEVYSIHREAPSYEEQSNETALLETGVKVIDLVCPFAKGGKIGLFGGAGVGKTVNMMELINNIALQHSGLSVFAGVGERTREGNDFYYEMQEAGVVNVENPEESKVAMVYGQMNEPPGNRLRVALTGLTMAERFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKQGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLNRNIAAMGLYPAIDPLDSTSRQLDPLVVGQDHYDTARGVQQTLQRYKELKDIIAILGMDELSEEDKQVVSRARKIERFLTQPYHVAEVFTGDPGVYVPLKETLRGFKGLLAGEYDDIPEQAFMYCGTIDDAIENAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 1, ATP synthase F1 sector subunit beta 1, F-ATPase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEUC_PYRNV
Sequence: MPTWTEYIFQRKLGRAPSPGDVVEVVPDLVGFHDLTGYHVLEVLESMGKVEVFDKGRVVVAFDHLSPPPTQRAAEIMVYIRKHVKALGLPNFYDVGGGILHQIILEKYAMPEYVIFAADSHTNTAGAVGAFAHGMGATDIAAALKLGRTWVVVPAPFRVDVRGEFPPGVMGKDVALHLLKQFGAEGFNGYSVEVFVERPKAFPMDDRATVANMSTEMGADALMFIPDEVTADYLQRERGVSYKPPSLEPGRYVDRYEVELQRLEPLVAAPYSVDNVKAAREVEGVEVDQVFIGSCTNGRLSDFEVAARVLKRGRAKARCIAIPASYAVFRRAMELGYIDVLTKAGCVVTYGTCGPCLGGHFGVAGPGEVVVTTSNRNFKGRVGHPDSKVYLANPATAAAAALEGKIVDPRPYLAP
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: RR11_PIPCE
Sequence: MTKPIPRIGSRRSGRIGSRKAGRRIPKGVIHVQASFNNTIVTVTDVRGRVVSWSSAGTCGFKGTRRGTPFAAQTAAGNAIRTVVDQGMQRAEVMIKGPGLGRDAALRAIRRSGLLLSFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CLCA_SALPC
Sequence: MKTDTSTFLAQQIVRLRRRDQIRRLMQRDKTPLAILFMAAVVGTLTGLVGVAFEKAVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGCVGPVFNSLVLRTQDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPEAAGGGFNLIPIAAAGNFSVGLLLFIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILARTLAKQDAEQAAKNQNASAGENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DTD_CLOBK
Sequence: MRAVVQRVISSKVEVDGKVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENEKLNKSLLDIGGDIIIVSQFTLYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNVATGEFGADMKVYIENDGPVTILLDSKKTF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_ALIF1
Sequence: MSIELDLQIACENENGLPSEKELMTWLNAVIPQFQPQAELTIRIVDEKESHELNHEYRGKDKPTNVLSFPFEAPPGLELNLLGDLIICRQVVEEEAIEQNKPLLAHWAHMVVHGSLHLLGYDHIEDDEAEEMESLETELMQGMGFEDPYIAEK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_GEOSM
Sequence: MARKKIALIGGGQIGGVLAQLAALRELGDVVMFDIVEGLPQGKMLDIAEVGSVDGFDCNLKGTNSYEDIKGSDVVIVTAGLPRKPGMSRDDLIEVNSKIMTSVAEGIKANAPNAFVIVISNPLDAMVTLCQKITGFPYNRVIGQAGVLDSARFKTFIAWELGVSVKDVNAMTLGGHGDDMVPLVRYASVNGIPVMELLERKYKDKAKAKEVMDAMVKRTRGAGGEVVALLKTGSAFYSPASSAIQMAESILKDQKRVLPTCAYLNGEFGVKGFYVGVPCVLGENGVEQILEFELDAEEQAMMDKSVAAVKELVGSMK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: RIR2_EHV4
Sequence: MALENSKKTDFADELLINAYFYTPECPDIEHLRLLSVANRWLDTDLPISDDLKDVAKLAPAEREFYRFLFAFLSAADDLVNLNLGDLSALFTQKDILHYYIEQESIEVTHSRVYSAIQLMLFGNDATARARYVASVVKDVAIDLKVSWLQAKVRECKSVAEKYILMILIEGVFFASSFASIAYLRTHNLFVVTCQSNDLISRDEAIHTNASCCIYNNYLGGFEKPAPTRIYALFSEAVNIECEFLLSHAPKSSHLLDIEAIICYVRYSADRLLGEIGLSPLFNAPKPPPSFPLAFMTVEKHTNFFERRSTAYSGTLINDL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: SIXP1_MESMA
Sequence: KKNGYAVDSSGKVAE
What is the function of this protein?
Excitatory insect beta-toxins induce a spastic paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  This toxin shows an evident analgesic effect on mice, but is devoid of mammalian toxicity.
What are the official names of this protein?
Insect toxin BmK AngP1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MSX1_HUMAN
Sequence: MAPAADMTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT
What is the function of this protein?
Acts as a transcriptional repressor.  May play a role in limb-pattern formation.  Acts in cranofacial development and specifically in odontogenesis.  Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity.
What are the official names of this protein?
Homeobox protein MSX-1, Homeobox protein Hox-7, Msh homeobox 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDPA_DESDA
Sequence: MENIIWQCLLYLSLLTALAWPLGKYIGKVMDGEPFWLQRALAPCERALYRLMGVDPAEQMGWKCYMACVIAFSAVSLVALTALLMAQHLLPLNPRNVSGASWHLALNTAISFVTNTNWQSYAGESTMSYLSQMAGLTVQNFVSAAVGIAVLFALIRGVRASGGIGLGNFWADATRAVLYILLPLSLVMSLLLIEQGVPQNFTDYRAAALLEPLAAEDGAPITHQLVPMGPQASQVSPKQLGTNGGGFNGVNSAHPHENPTPASNMLEMLALLLIPAALCFTFGAKIGDMRQGVAIFAAMFILLTSAVSFTVQAELNATPQIAQGGQVLVAPQSGLQGQAGGNMEGKETRFGIAGSALWASATTAVSNGSVNAMHDSFTPLGGMIPMVLMQLGEVIFGGVGSGLYGMLAFVLLTVFLAGLMVGRTPEYLGKKIEPFEMKMAVVVCLTTPVVILAGGGLMCLAPQIVDSLNNPLPHGFSEILYAATSAGANNGSAFAGLNANTPFLNVLLGVLMLAGRFAPIAAILAMADGLAGKKICPPGAGTLSTCNGLFIFLLIFVILLVGALSFFPALALGPLAEHLQMTR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROBE_OLEEU
Sequence: MSWQTYVDDHLMCDIEDHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVCGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-3, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PRCLN_TRIPT
Sequence: MKTFIVITFIGILSYAYADECENPEPMQGFSASQFYQGXWYVTHETSAXTLSECNILTTSNDNGKFTVKHKYTKDGXVGELICEGQASANNKFTYDCKFXGZTMEQVTRTAMDTDYNDYALYYLCTTYKXGPNAGKKEGHYILSRRQPNTEIPDALKTKTKDLNLKLCG
What are the official names of this protein?
Procalin.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Triabin family.
What are the subcellular locations of this protein?
Secreted.