PharMolix/UniProtQA huggingface dataset:
Protein: QUEA_CUPNH
Sequence: MLTLSDFDFPLPPELIAQSALPDRSASRLLVVERLAPADTADAVRMVDRAFSDIVDYLRPDDLLVFNDTRVIKARFFGHKPSGGKIEVLVERVVDSHTVLAQVRASKTPTEGSILHLADGAFAVTVGPRVDQFFTLRFPEPALDLIERYGRLPLPPYIRHDPDAYDETRYQTVYARSPGAVAAPTAGLHFDDALFARLNAAGVRRAFLTLHVGAGTFQPVRTENLAEHKMHSEWYAVSADLAQAVRDTRARGGRVIAVGTTSLRALESAAQADGTLAAGSGDTDIFITPGYRFRLVDALITNFHLPKSTLLMLVSALAGVEAIRAAYRHAVEQRYRFFSYGDAMLLTRQPGA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRT85_HUMAN
Sequence: MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSGPSAIGGSITVVAPDSCAPCQPRSSSFSCGSSRSVRFA
What are the official names of this protein?
Keratin, type II cuticular Hb5, Hair keratin K2.12, Keratin-85, K85, Type II hair keratin Hb5, Type-II keratin Kb25.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RL16_SHESA
Sequence: MLQPKRMKFRKMFKGRNRGLANGTEVSFGTFGLKAVGRGRLTARQIESARRAMTRHIKRQGQIWIRVFPDKPITSKPLEVRMGKGKGNVEYWVCQIQPGKVLYEMNGVSEVIAREAFALAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: METK_NEIM0
Sequence: MSEYLFTSESVSEGHPDKVADQVSDAILDAILAQDPKARVAAETLVNTGLCVLAGEITTTAQVDYIKVARETIKRIGYNSSELGFDANGCAVGVYYDQQSPDIAQGVNEGEGIDLNQGAGDQGLMFGYACDETPTLMPFAIYYSHRLMQRQSELRKDGRLPWLRPDAKAQLTVVYDSETGKVKRIDTVVLSTQHDPEIGYEELKNAVIEQIIKPVLPSELLTDETKYLINPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYACRYVAKNIVAAGLATQCQIQVSYAIGVAEPTSISIDTFGTGKISEEKLITLVREHFDLRPKGIVQMLDLLRPIYSKSAAYGHFGREEPEFTWERTDKAAALRAAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_STRSY
Sequence: MEVKPLANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELFRAASSAIDKAETKGLIHKNKASRDKARLASKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: DEF5_MESMA
Sequence: MKVIALFFLFAFIFCTLEVAIVEAGFGCPLNQGACHRHCLSIRRRGGYCSGFFKQTCTCYRN
What is the function of this protein?
Antibacterial peptide active against Gram-positive bacteria (including S. aureus ATCC25923 (MIC=2. 5 uM), M. luteus AB93113 (MIC=2. 5 uM), and the antibiotic-resistant S. epidermidis PRSE P1389 (MIC=1. 25 uM)), but not against Gram-negative bacteria (including E. coli and P. aeruginosa).  Has also weak blocking activity on Kv1. 1/KCNA1 (8. 7% inhibition), Kv1. 2/KCNA2 (10. 2% inhibition), Kv1. 3/KCNA3 (9. 0% inhibition), KCa3. 1/KCNN4/IK (9. 1% inhibition), KCa2. 3/KCNN3/SK3 (46. 3% inhibition) and Kv11. 1/KCNH2/ERG1 (16. 9% inhibition) channels (tested at 1 uM) (PubMed:31954123).  It inhibits potassium channel current by interacting with the pore region (By similarity).
What are the official names of this protein?
Defensin BmKDfsin5.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_BURM9
Sequence: MALERTLSIIKPDAVAKNVIGQIYSRFENAGLKIVAARMAHLSRADAEKFYAVHAERPFFKDLVDFMISGPVMIQVLEGEDAILKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAPETARAEVAFFFPEMNVYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN383_HUMAN
Sequence: MAEGSVMFSDVSIDFSQEEWDCLDPVQRDLYRDVMLENYGNLVSMGLYTPKPQVISLLEQGKEPWMVGRELTRGLCSDLESMCETKLLSLKKEVYEIELCQREIMGLTKHGLEYSSFGDVLEYRSHLAKQLGYPNGHFSQEIFTPEYMPTFIQQTFLTLHQIINNEDRPYECKKCGKAFSQNSQFIQHQRIHIGEKSYECKECGKFFSCGSHVTRHLKIHTGEKPFECKECGKAFSCSSYLSQHQRIHTGKKPYECKECGKAFSYCSNLIDHQRIHTGEKPYECKVCGKAFTKSSQLFQHARIHTGEKPYECKECGKAFTQSSKLVQHQRIHTGEKPYECKECGKAFSSGSALTNHQRIHTGEKPYDCKECGKAFTQSSQLRQHQRIHAGEKPFECLECGKAFTQNSQLFQHQRIHTDEKPYECNECGKAFNKCSNLTRHLRIHTGEKPYNCKECGKAFSSGSDLIRHQGIHTNK
What is the function of this protein?
May function as a transcriptional repressor, suppressing transcriptional activities mediated by MAPK signaling pathways.
What are the official names of this protein?
Zinc finger protein 383.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttling between the nucleus and cytoplasm may occur under different stimulation and growth conditions.
Protein: ANDAC_BURCE
Sequence: MEQTASPVVFAARDDASDVHFPHDDGSRVPYKVFSSRAVYDREQERIFRGPTWNFVALEAEIPNAGDFKSTFVGDTPVVVTRTEDGALSAWVNRCAHRGAQVCRKSRGNASSHTCVYHQWSFDNEGNLLGVPFRRGQKGMTGMPADFDPKQHGLRKLRVDSYRGLVFATFSDDVAPLPDYLGAQMRPWIDRIFHKPIEYLGCTRQYSKSNWKLYMENVKDPYHASMLHLFHTTFNIFRVGMKARSIPDANHGLHSIITVTKTGDDTSAAYKQQNIRSFDEGFHLEDESILDLVSEYDEDCTNHIQPIFPQLVIQQIHNTLVARQILPKGPDNFELIFHFFGYADDTPELRALRIKQANLVGPAGYISMEDTEATELVQRGTVRDADATSVIEMSRGNPEQQDTVITESLIRKFWVGYQKLMGY
What is the function of this protein?
Oxygenase component of anthranilate dioxygenase multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into anthranilate to form catechol.  Can also act on benzoate and salicylate but not on 2-chlorobenzoate or o-toluate.
What are the official names of this protein?
Anthranilate 1,2-dioxygenase large subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: AK1A1_XENTR
Sequence: MATAVEYETLYTGQKIPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGSDKGLSREEVFVTSKLWNNKHHPDDVECALRKTLQDLQLDYLDLYLMHWPYAFKRGDQIFPQNPDGSVQYDLTDYKDTWKAMEKLVKQGLTKAIGLSNFNKRQIDDIISIATVKPAVLQVECHPYLAQNELIAYCHAHGLVFTGYSPLGSPDRSWRKPEDPVLLEEPGIIAMAKKYGKSEAQILLRWQVQRKVVSIPKSVTPTRILQNFQVFDFSLSEEEMQLIGALNKNWRYIIPLITVNGKSVPRDAGHPLYPFNDPY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols.  Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids.  Acts as an aldehyde-detoxification enzyme (By similarity).  Displays no reductase activity towards retinoids (By similarity).
What are the official names of this protein?
Aldo-keto reductase family 1 member A1, Alcohol dehydrogenase [NADP(+)], Aldehyde reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Apical cell membrane.
Protein: MAT1_EUGLO
Sequence: MISFSLINFSNNLSWDKVTNLIFKLQKRLFKVSYVYDRKKLYVLQKIIVQLNYSRLLAIKLVNHSVFNENLPGVDGYVSLNFYESFELNEFLKYNWNNWIFQNLKKVSLFDNDGKIIVKKVPVISDRVWCYLVKFAIEPVHEALFHPFNLGYRSQYFIYEIQELILLNLSKFSFGSKKRVLKLDLSQNFCINNYSFLMEKLIAPRCIKLGIFKLLEKGFVLEFSNNCIFNKVDFSSLLLNIFLNGIEKLHNCIRYGYFLLFFLNPIDNEKELLSKIYLFLSKLDLKFNISEIELSSIINGFDFLGWHFKFSYKSYNNLCIFPSFDNYNKFLTRIKVIINNSNYGSIIKASKIYPIVKDWKEYHKYSDLFDLNYSLCFIKKRAFKIFKSESKQDFYSSKSLLLKCFSVFNIFNKDLKNLYNKFFKPLNFRHLVFLFNRGGEGFKYFYFCIHCGVILL
What is the function of this protein?
Could be required for group III intron excision.
What are the official names of this protein?
Maturase-like protein 1.
What is the protein family that this protein belongs to?
To group II intron maturases.
What are the subcellular locations of this protein?
Plastid.
Protein: LPXA_STUS1
Sequence: MSLIDPRAIIDPAARLADDVQVGPWSIIGPDVEIGEGTVIASHVVIKGPTRIGRHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRSETTIGDHNLIMAYAHIGHDSVIANHCILVNNTALAGHVHVGDWAILSGYTLVHQFCHIGAHSFSGMGTAIGKDVPAFVTVFGNPAEARSMNFEGMRRRGFSAEAVHALRNAYKIVYRKGLTVEAALSELAESAAAFPEVAIFRDSIQASTRGITR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
Protein: RS182_MYCVP
Sequence: MAKSSTKRRPAPEKPVKTRKCVFCSKKGKNQDIDYKDTQLLRTYISERGKIRARRVTGNCVQHQRDIAIAVKNAREVALLPFSSSTR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: AKR3_ORYSJ
Sequence: MAAAAATAPAAAVVRRMKLGSQGMEVSAQGLGCMGMSAVYGERKPEADMVALVRHAVAAGVTFLDTSDVYGPHTNEVLVGKAVAAAAATEEEVQVQVATKFGITPAWEVRGDPAYVRAACEGSLRRLGVGCIDLYYQHRIDSTVPVEITMGELKKLVEEGKIKYIGLSEASASTIRRAHVVHPITAVQIEWSLWSRDVEEDIVPTCRELGIGIVAYSPLGRGFFSSGAKLVDELPDDDFRKSLPRFQPENLEKNAAIFEKVNAMAARKGCTSSQLALAWVHHQGSDVCPIPGTTKIHNFDQNVGALSVKLTPDEMSELESYASADVVQGDRYHGTFLNTWKNSETPPLSSWRSGN
What are the official names of this protein?
Probable aldo-keto reductase 3.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: RTCB_OSTTA
Sequence: MAPATEAAPARTYDDEAAYVTVDDAHRVRVARGFVPNMRVDGVVYVNAALRALVLEELAAYCDATAHRGGGYSPALKQIANVAALPGVVGASIALPDVHSGYGFAIGNVAAFDVGDETSIVSPGGVGFDINCGVRLLRTNLTEAEVGPVKEALAQSLFDHIPVGVGSRGIIPTTPAALEAVLEMGMDWSLREGYAWAEDKEHTEEYGRMLNADPSKVSARAKKRGLPQMGTLGAGNHYAEIQVVDEIYDEFAAKKMGIDRVGQVCIMIHSGSRGLGHQVATDSLTAMERAMERDGIEVNDRQLACARISSQEGQDYLAAMACAANYAWVNRSSMTFLCRQAFAKMFGKPPDELDMHVVYDVSHNIAKFEEHMVDGEMKTLLVHRKGSTRAFPPHHPLIPVDYQYTGQPVLIGGTMGTCSYILTGTEKGMRDTFGSTCHGAGRARSRNKSRHVLQYEDVLEKLKTKGIAIRVASPKLVMEEAPESYKDVTEVVNTCHDAGISKKCVKLRPIAVVKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: RL15_ANADE
Sequence: MSLNQLKAPRGANRAKKRVGRGQGSGLGKTAGRGGKGQKARSGNMHFEGFEGGQMPLQRRLPKFGFHNIFRRELEEVKVGDLQGLSGVVDPAALKSAGLVRGNRDGVVVLAGGELSSALTVKVHRVTAGARAAIEKAGGKVELIPAPQTMHQKAKAAKKAAAQAK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: GET3_TALMQ
Sequence: MSSTALIHDDEALEPTLQSILDQKTLRWIFVGGKGGVGKTTTSCSLAIQLSKVRKSVLLISTDPAHNLSDAFGQKFGKEARLVDGFTNLSAMEIDPNGSIQDLLASGGEAQEDPLAGLGMGGMMQDLAFSIPGVDEAMSFAEVLKQVKSLSYEVIVFDTAPTGHTLRFLQFPTVLEKALAKLSQLSSQFGPMLNSILGSRGGLPGGQNLDDLMSKMESLRETISEVNTQFKNPDMTTFVCVCIAEFLSLYETERMIQELTSYGIDTHAIVVNQLLFPKKDNPCEQCNARRKMQKKYLEQIEELYEDFNVVRMPLLVEEVRGKEKLEKFSEMLVKPYVPPE
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase get3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: BIOB_ACIF2
Sequence: MNNSTALQTLDAILEIYARPFNDLIYAAQQVHRLHFDPNAIQCSTLLSIKTGGCPEDCGYCSQSVHHQTALQAEPLMDLEQVRAAAREAKANGAQRLCMGAAWRSPHDRDIEKVAAMIGVVKEYGLESCVTLGMLKPGQAERLQHAGLDYYNHNLDTSPEFYGEVIHTRSYQDRLDTLEAVRDAGIRICSGGILGMGESRRDRARMLQVLAQLPQAPESIPINALVPIPGTPLEAAEPIDGFEFVRTVAVTRILFPKAYVRLSAGREAMSDELQALAFLAGANSIFLGDRLLTTGNASTGHDQALFNRLGLHRSAD
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ISPE_HAHCH
Sequence: MRNETLTLSSPAKLNLFLHITGRRPDGYHELQTLFQLLDYGDSLSFTPRDDQRITLEPSLPGVPEADNLIIKAARLLKEHITATSPDKAGQISGVSIYINKKLPMGGGIGGGSSNAATTLLALNRLWNADINTETLAALGLKLGADVPVFVRGATAFAEGVGDILHPVDTQEKWYLVVHPNLHISTAKIFSDKWLTRDTPKSTIAPALEGDLENLRNDCETVVCRMYPEIREAINWLDQFSPARLTGTGACIFASFSDKKRAEYVLSQMPTKYQGFVAKSINESPVLNELKQWRNH
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SYY_SALTY
Sequence: MASSNLIKQLQERGLVAQVTDEDALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVAKIRKQVAPFLDFDCGENSAIAANNYDWFGSMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDQGISFTEFSYNLLQGYDFACLNKLHGVALQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMDIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLVAAKRITECLFSGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDAELQPSRGQARKTIASNAVTINGEKQSDPEYIFNDEDRLFGRYTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBLL1_HUMAN
Sequence: MKSAASSRGGGGGGRGGGGWGSWGGGRGGGGGAGKGGGGDGGGQGGKGGFGARARGFGGGGRGRGRGGGDGKDRGGGGQRRGGVAKSKSRRRKGAMVVSVEPHRHEGVFIYRGAEDALVTLNMVPGQSVYGERRVTVTEGGVKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYRPLPKSSSK
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins.  Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA.  Also acts as a protein methyltransferase by mediating methylation of glutamine residues (By similarity).
What are the official names of this protein?
rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1, Protein-glutamine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Fibrillar region of the nucleolus.
Protein: STAR3_HUMAN
Sequence: MSKLPRELTRDLERSLPAVASLGSSLSHSQSLSSHLLPPPEKRRAISDVRRTFCLFVTFDLLFISLLWIIELNTNTGIRKNLEQEIIQYNFKTSFFDIFVLAFFRFSGLLLGYAVLRLRHWWVIAVTTLVSSAFLIVKVILSELLSKGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQVAVARGPLLFSGALSEGQFYSPPESFAGSDNESDEEVAGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKFEKNNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLISYDVSAGAAGGVVSPRDFVNVRRIERRRDRYLSSGIATSHSAKPPTHKYVRGENGPGGFIVLKSASNPRVCTFVWILNTDLKGRLPRYLIHQSLAATMFEFAFHLRQRISELGARA
What is the function of this protein?
Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes (PubMed:11053434, PubMed:15930133, PubMed:22514632, PubMed:28377464).  Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum via interaction with VAPA and VAPB (PubMed:24105263, PubMed:28377464).  Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes (PubMed:28377464).  May also mediate cholesterol transport between other membranes, such as mitochondria membrane or cell membrane (PubMed:12070139, PubMed:19965586).  However, such results need additional experimental evidences; probably mainly mediates cholesterol transport from the endoplasmic reticulum to endosomes (PubMed:28377464).  Does not activate transcriptional cholesterol sensing (PubMed:28377464).  Able to bind other lipids, such as lutein, a xanthophyll carotenoids that form the macular pigment of the retina (PubMed:21322544).
What are the official names of this protein?
StAR-related lipid transfer protein 3, Metastatic lymph node gene 64 protein, MLN 64, Protein CAB1, START domain-containing protein 3, StARD3.
What is the protein family that this protein belongs to?
Belongs to the STARD3 family.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Note=Localizes to contact sites between the endoplasmic reticulum and late endosomes: associates with the endoplasmic reticulum membrane via interaction with VAPA, VAPB or MOSPD2.
Protein: DCD_SHESM
Sequence: MRLTDIEIEQALDNGSIVIEPRPSNDAISGVSVDVRLGGQFRVFKDHTAPFIDLSGPSTEVQAALDRVMSEIIEIPDGEAFFLHPGELALAVTYESVTLPADIVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFYNSGKLPLALRPRMTIGALNFERLSGPVARPYNKRKNAKYKDQQDAVASRISQD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: S23A2_XENTR
Sequence: MGIGRNPSSKAMESTNSTDGKYEEESKHTAFFTLPAVINGGAASSGDQDTEDTELMAIYTTESGIAEKSSLAETLDSTGSLDRQRLDMIYTVEDVPPWYLCIFLGLQHYLTCFSGTVAVPFLLAEAMCVGFDQWATSQLIGTIFFCVGITTLFQTTFGCRLPLFQASAFAFLAPARAILSLEKWKCNTTDLSITNGTELLHTEHIWYPRIREIQGAIIMSSLIEVVIGFLGLPGALLKYIGPLTITPTVSLIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKLPLPIYKSKKGWTAYKLQLFKMFPIIMAILVSWLLCFIFTVTDVFPPDSSKYGYYARTDARQGVLTVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFIEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVASRRVIQYGAAFMLLLGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFVDLNSSRNLFVLGFSIFFGLMLPSYLKQNPLVTGIAEIDQVLNVLLTTAMFVGGCTAFILDNTIPGTPEERGIRKWKRGVGKGTSGIEGMESYDLPFGMGFLRRYKCFSYLPISPTFAGYQWKALRKCGSCPRAAEEEPEPAV
What is the function of this protein?
Sodium/ascorbate cotransporter.  Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.
What are the official names of this protein?
Solute carrier family 23 member 2, Na(+)/L-ascorbic acid transporter 2, Sodium-dependent vitamin C transporter 2.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNTR_BACAN
Sequence: MPTPSMEDYIEQIYLLIDEKGYARVSDIAEALSVHPSSVTKMVQKLDKDEYLIYEKYRGLVLTSKGKKIGERLVYRHELLEQFMRIIGVDESKIYNDVEGIEHHLSWEAIDRIGDLVQYFEQDEVRVETLRGVQKANEEKSN
What is the function of this protein?
Central regulator of manganese homeostasis.
What are the official names of this protein?
HTH-type transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1857_BACC2
Sequence: MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAGVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSTGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINKIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDEHAS
What are the official names of this protein?
UPF0316 protein BCG9842_B1857.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL24_FRATF
Sequence: MNRLKKGDDVIVIAGKDKGRRGVVKSFAKGGSLVLVEGINIVKKHIKPNPNRGIEGGVVEKELPVDASNVAIFNPATEKADRVGYKFVDEKKVRYFKSNGELVDL
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: Y043_METJA
Sequence: MIANVDLHIHSRFSGGTSKDMNVENILKYGKLKGLNIIGTGDCTHPDYLEEIKQYKDRELILTTEIEDKNRVHHLILLPSISKVEELREILKKYSKDIDKEGRPRVSIGGAELLEIVRDVGGLIGPAHCVPPDTLLILENGFKRIVDIKVGDKVLTHENRFKKVEKVYKRRYIGDIIKIKVRYFPEEIILTPEHPVYAIKTEKRCDGSHGICKFNCLTQYTNPSCKKRYRKYKREWIIAKDLKVGDVIVYPIPNRVRDIKYLSLDKYLSNIKREFCRSRIPEKIEVSEEFCRLVGYFLSEGYCFRDGIGFALGENEKKIIDDIEYLMKKIFNLKPKIRDDGRSEGIELKYYSRVLRDFFGDMFYCGDEKRAWNKALPNEFLYLPKNKQLQIFIGWWRGDKGVTTSEILMNQLRLISLRLGFIITFSKHVPKNPKIGDREVIKYHARWQGRVSILDEKIVDELKNEDIKLPKKDVRYGWIKGNYLYAPIIRIGREYYDGFVYNLEVEDDSSYVTVSGTLHNCFTPWTSLYKSFDSIYDCYNKKPDFVELGLSADTDMADMIPELRDLPFLSNSDAHSYHPHRLGREFNQIEVDYIGGIEDNFEQIKKAIKHNKIIANYGLDPKLGKYHLTACSKCHTRFKLEDAKKYNWKCPKCGGSIKKGVLSRVEELSDGKIEHPKFRPPYYKLIPLAEMISLTIGKGIFTKAVQSLWEEFIKKYGNEIEVLINADIDELSKIHPKVAETINLFRKGKIYIYPGGGGEYGKISFKPQKVEWYREEVTLDRWLKQ
What are the official names of this protein?
Uncharacterized protein MJ0043.
Protein: YNFC_ECOLU
Sequence: MKYKLLPCLLAIFLTGCDRTEVTLSFTPEMASFSNEFDFDPLRGPVKDFTQTLMDEQGEVTKRVSGTLSEEGCFDSLELLDLENNTVVALVLDANYYRDAQTLEKRVRLQGKCQLAELPSAGVSWETDDNGFVIKASSKQMQMEYRYDDQGYPLGKTTKSHDKTLSVSATPSTDPIKKLDYTAVTILNNQRVGNVKQSCEYDSHANPVDCQLIIVDEGVKPAIERVYTIKNTIDYY
What are the official names of this protein?
UPF0257 lipoprotein YnfC.
What is the protein family that this protein belongs to?
Belongs to the UPF0257 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.