PharMolix/UniProtQA huggingface dataset:
Protein: HIS4_ECOBW
Sequence: MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVGSTAVKSQDMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTGVRGVIVGRALLEGKFTVKEAIACWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPP7_ARATH
Sequence: MDHKAWPWKKKSMEKTVVESNGEVVADKIELEHRVKSLNDKLNSVEAESNKHETEAQEAIVGWEKTKAEVASLKKKLDEALNEKHRSEERSSHTDAGLKECVQQLRFVREEQERRMHDALTKASQEYERRLIVIKTELAGSGKRLAEAEGENAQLSKALLAKNKTVEDLNRERDRIEVDFNSLVSSLESKEKENVSLRYEVRVLEKELELRNEEREFSRRTAEASHKLHLENVKKVAKLESECQRLRVLVRKRLPGPAALSKMSNEVEMLGRRRVNGSPHSPMIDSEKINNLTEQLCLLEEENKTLREALNKKVSELQFSRNMYSRTASRLLEFESHLEESSRGTNIEPSRSSNVSHEVSLASVTEFDNDDKVSCADSWASALLSELDNFKNKKEMGTSLVGTPKAAEMKLMDDFAEMEKLAMVASTIDNRPGSSPICSSDSISATGPVENESNENSSEATKTSGTVYSLNPDASPKDDIKSDSLPQSLHIVLKAVMEHKHITQRNTDEVLEDIRKALSSVNHSSFSTNHQETKTLTVEDRLDMECNISKSIHRIIDVIEGVSLKDERHVSNRESERLSGYTARVLQWKTTELSSVLQRFLQACYDLLDRKADMKKFAQELSSVLEWMVNHCFSLQDVSTMRDEIKKQFEWDESRSGSEVDIGIFRQVSEAEKLRTEDVSFLACKDQLIEDKPGNQNLSRKTVEEEANDKTASASENELKLEEKQNMRTELEIAAASEKLAECQETILNLGKQLKALTNSKETALLSETLMYDVTDKSNNLPDAQPSHETTKPEKRLTSQRSSLLDQMKAEDHNTGESKDQKPQAADKNGKGGNSSVYNETIEALEQILLSDKSKGSDSNCFAIVPQKKTGGVKSLWRKLLGRNKKGKSKKVPNPFAN
What are the official names of this protein?
Filament-like plant protein 7, AtFPP7.
What is the protein family that this protein belongs to?
Belongs to the FPP family.
Protein: RPO3_METS3
Sequence: MEIEVKSQTDDEIVFIVRDAEVPFINAIRRCAMVNVPKIAIEDVNIMRNDSAMFNEVLAHRLGLTPLVSNMDAIEGLPLPGDDDYEENNSVMFSLKEEGPKVVYSKDLISSDSKIKPVYDTIPLVKLKEGEKLNIEAVAKVGYGKEHAKWMPTTVCVYKQYPEITFNEDVGIDYECADACPRGVLKSDKRSKEIKILDIEDCAMCKSCVRASIRNAQSEGKDESYINVGYHENDFIFRIETDGSMPPKEVLLQACDELGEKADKFIRFSEGGSK
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo3, DNA-directed RNA polymerase subunit D.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_BURMA
Sequence: MKVVAFERQQQGTGASRRLRNAGKTTGIVYGGEAAPQMIELDHNALWHALKKEAFHSSILDLEVAGKSQRVLLRDVQYHPFRQLVLHVDFQRIDPKKKLHTKAPLHFLNAETSPAVKLSSAVVSHVVTEIEIECLPADLPEFLEVDLSKIEAGQSLHAKDIALPNGVALTAHVDAENPVIASATIPAGAVSDEAAAGEGETPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: PMM1_DICDI
Sequence: MSLVPNTICLFDVDGTLTKPRNVITPEMKDFLAGLRTKVELGVVGGSDINKIKEQLGENCINEFHYLFAENGLLSFKDGSLLATQDIKKFLGEENIKKFINFVLHYIADLDIPIKRGTFVEFRNGMINISPIGRNCSQQEREEFEKYDLEHKIRPTMVSILKEKFQSLGLQYSIGGQISFDVFPIGWDKTYCLRHLPEDKYKTIYFFGDKTFVGGNDYEIANDPRITKSFTVTSPTDTKNFLSELFYKQ
What is the function of this protein?
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
What are the official names of this protein?
Phosphomannomutase 1, PMM 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic PMM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_MYCBT
Sequence: MAATLRELRGRIRSAGSIKKITKAQELIATSRIARAQARLESARPYAFEITRMLTTLAAEAALDHPLLVERPEPKRAGVLVVSSDRGLCGAYNANIFRRSEELFSLLREAGKQPVLYVVGRKAQNYYSFRNWNITESWMGFSEQPTYENAAEIASTLVDAFLLGTDNGEDQRSDSGEGVDELHIVYTEFKSMLSQSAEAHRIAPMVVEYVEEDIGPRTLYSFEPDATMLFESLLPRYLTTRVYAALLESAASELASRQRAMKSATDNADDLIKALTLMANRERQAQITQEISEIVGGANALAEAR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MDM12_SCHPO
Sequence: MSIDFDWSKLDSELEAKVLHLLEGQVSNLSLPSYIKHLKVVDFHFGKVSPQITIQEIGDPDPQFYENEAFELANQELEGDQCSRNNVSPVLTDLPPYAAEHPFSRLAYFNPAFNSPGILSASGLTSPIPESRPSTPMDNHQERDRSNDFQVTAHVSYDGDANLSLEAVLSMNYPNSEFAVLPFKLSFIRISIDAIAVLAKMGKRTHLCFVDTLLHGTGEHASSVIRDLTVESIIGESNKQLLKNVAKVEKFVSEKVKRIIEDELVWPSYITIE
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component mdm12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: UL13_HHV2H
Sequence: MDESGRQRPASHVAADISPQGAHRRSFKAWLASYIHSLSRRASGRPSGPSPRDGAVSGARPGSRRRSSFRERLRAGLSRWRVSRSSRRRSSPEAPGPAAKLRRPPLRRSETAMTSPPSPPSHILSLARIHKLCIPVFAVNPALRYTTLEIPGARSFGGSGGYGEVQLIREHKLAVKTIREKEWFAVELVATLLVGECALRGGRTHDIRGFITPLGFSLQQRQIVFPAYDMDLGKYIGQLASLRATTPSVATALHHCFTDLARAVVFLNTRCGISHLDIKCANVLVMLRSDAVSLRPAVLADFSLVTLNSNSTISRGQFCLQEPDLESPRGFGMPAALTTANFHTLVGHGYNQPPELSVKYLNNERAEFNNRPLKHDVGLAVDLYALGQTLLELLVSVYVAPSLGVPVTRVPGYQYFNNQLSPDFAVALLAYRCVLHPALFVNSAETNTHGLAYDVPEGIRRHLRNPKIRRAFTEQCINYQRTHKAVLSSVSLPPELRPLLVLVSRLCHANPAARHSLS
What is the function of this protein?
Multifunctional serine/threonine kinase that plays a role in several processes including egress of virus particles from the nucleus, modulation of the actin cytoskeleton and regulation of viral and cellular gene expression.  Regulates the nuclear localization of viral envelopment factors UL34 and UL31, by phosphorylating the US3 kinase, indicating a role in nuclear egress.  Disrupts host nuclear lamins, including LMNA and LMNB1.  Phosphorylates the viral Fc receptor composed of glycoproteins E (gE) and I (gI).  Phosphorylation of glycoprotein E (gE) by UL13 alters its subcellular localization, from the host early endosome to the plasma membrane.  Participates in the transcriptional regulation of cellular and viral mRNAs mainly by phosphorylating the viral transcriptional regulator ICP22.  Additional substrates have been identified, including UL41, UL49 or host EF1D (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase UL13.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus.
Protein: MNMC_ACTSZ
Sequence: MHHIQTADLRFSADNTPVSDRFDDIYFSTQDGVAESRYVFQQGNALWERWSACQDIHFVIAETGFGTGLNFFAVTTLFRQFRRQNPQSPLSRLHFISFEKYPISAEQLAITYQTFSEFSALAAQLQQWWQINGIPIEGCYRYHFGETTLDIWFGDVNTQLPQLGDYMQNRIDAWFLDGFSPSKNPDMWNETVYRLMYRYTKPQGTFATFTAASAVKKGLESAGFRVEKRAGFGKKRECLYGEKPAENAPHFTASQVNTPWFLPQAAKFDGAADVAIIGGGIASLFSALSLLERGADVTLYCEDDELALNASGNKQGAFYPQLSDDDERNIRFYIHAFAYGLQRLQWAVAHNVPFEHRFCGVALCGYDEKSAAKLDKISAYQWDKKLYAGMNREELAQTVGLPLPCGGGFIPNGGWLAPRQFVQNAFRLLESSGLSVKTAQKITALSSTKNGWTLQNAQGETFRHNIVVLANGHRLHRFEQTARLPLYPVRGQVSQIATGENLLKLNSVICYDGYMTPADEAKTSHCIGASHVRDCENREFSTTEQQENQAKIQKNLAMDWTHDVDTSDNRARVGVRCAVRDRIPMMGNVPDFDRQTEEYRNLFNLRRRKQPVLVAANFENLYLVGALGSRGLTSAPILGECLASLIYGEPLPLSEDIIHALCPNRSWMRKLLKGTPVK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSHB_PHOSU
Sequence: YCLTINTTICAGYCMTRDINGKLFLPKSALSQDVCTYRDFTYRTVEIPGCPHHVAPYFSYPVAMSCKCGKCNTDYSDCIHEAVKTNYCTKPQTFYLGGFSV
What is the function of this protein?
Indispensable for the control of thyroid structure and metabolism.
What are the official names of this protein?
Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH-B, TSH-beta, Thyrotropin beta chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSSA_PLAYO
Sequence: MSNKKVQSPKEESIAKMLICKVHIGTKNLENKMKRYVYTRAKDGVHIINLAKTYEKLQLAARVIVAVSNPADVVVVSARPFGSRAVLKFAQYTGAQAIAGRWTPGMLTNQIIQKFIEPRLLIVTDPRTDAQSVKESAYANIPVIALCDSDSPLEHVDIAIPCNNKGKESIALMYWLLAQEVLYLKGTIPRSQAWDVMVDMFLWRDPEQFELKNLANEEATPTAPHLADNQYATEAPYDDWNKKDDWNDNANEEWKNPITVDEW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_YERP3
Sequence: MRTSQYLLSTQKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRGEINSYKQLPLNFFQIQTKFRDEVRPRFGVMRAREFLMKDAYSFHTTQESLQETYDAMYTAYSKIFSRMDLNFRAVLADTGSIGGSASHEFQVLAESGEDDIVFSTGSDYAANIEFAEALAPTEPRAPATEELRIVDTPNAKTIAELVEQFKLPIEKTVKTLLVHAHEESGHKLVALLVRGDHDLNEIKAEKLPQVAKPLTFASEEEIRAAIGAGPGSLGPVNLSLPVIADRSVAVMSDFGAGANIDGKHYFGINWERDLALPLVADLRNVVEGDISPDGKGTLQIKRGIEVGHIFQLGTKYSEAMKATVQGEDGRNQVMTMGCYGIGVSRVVAAAIEQNHDDRGIIWPDAIAPFQVAILPMNMHKSFRVKELAEELYTTLRSHGIDVILDDRKERPGVMFADMELIGVPHNIVIGDRNLDSEEVEYKNRRVGEKQMIKTSEIVEFLLSQIKR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPZ_ENTHA
Sequence: MKQEFSVKGMSCNHCVARIEEAVGRISGVKKVKVQLKKEKAVVKFDEANVQATEICQAINELGYQAEVI
What is the function of this protein?
Acts as a copper chaperone by delivering 2 Cu(+) ions to CopY Zn(2+)-bound form.  This transfer results in displacement of zinc and dissociation of CopY from the promoter, allowing transcription of the copYZAB operon.
What are the official names of this protein?
Copper chaperone CopZ, Activator of copYZAB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: L1103_FRATN
Sequence: MKYGNLMMTKKKLLIGMVTISGIVILGSCGKTETVNELLIVDQCNDVRDLCRLELANAQVSRYTNFLGKTIKRLQSQTPLRDIQGTVTWNASAGTSLADNSDVQSELGLSCQDDNCTANSNSTAYTLPVGSNTISVSGTVTVDGKTIDLATDVPALVINTSAAGSSVHVFPTELEGNLTLQDLVDSLNQGRHYAHATFSADGSNLKIQCDPGYVWLDDINPEYGGQSSAASARSVAMVSWVEELEEFRVDEFRFLHFDMSSLTLNGVRLGNHVFWEMGCWPT
What is the function of this protein?
Stimulates the host immune inflammatory signaling system allowing the host to combat the bacteria.  Stimulates mouse interleukin-6 (Il6) production (PubMed:23584588).
What are the official names of this protein?
Bacterial lipoprotein FTN_1103, BLP.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: KYNU_BACAH
Sequence: MYKEPFQPTYEYALECDKHDELKDFQTEFYKKEGTIYLDGNSLGLLSKRAEKSLFTLLDSWKEYGIDGWTEGEHPWFFLSEKLGELTAPLIGALPEETIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPDEHLVRVKSRDGRTLSEDDIIHAMTDDVALILLPSVLYRSGQILDMKRLTAEAHKRGIHIGFDLCHSIGSIPHHFKEWDVDFAIWCNYKYLNAGPGGVAGLYVNKKHFNRLPGLSGWFSSRKDKQFDMEHTLTAADHAGAYQIGTPHVLSTAPLIGSLEIFKEAGIERLREKSLHITRFMLNLIAHELSDFGFTIGNPLEDEKRGGHIYLEHAEAARICKALKANGVIPDFRAPNGVRLAPVALYNTYEEVWHSVQILKKIMKDEEYKQFENKREVVA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: AAEA_PECCP
Sequence: MKAFFLTLFRQQAVLIKKMSRVAITLVIVLCAIVAIFRVWAFYTESPWTRDAKFTADVVAIAPDVSGLLSDVRVTDNQLVNKGDVLFVIDQPRYHQAVAQAEADVAYYQALVTEKRRESGRRARLGISAMSQENIDQSSNALETATHQLAKAQVVLSLAQLELERTVVRAPADGWVTNLHVQSGEFIERGNTAVALVKKDSFYLLAYMEETKLEGVRRGYRAEITPLGSEKIFYGTVDSVAAGVNNSSSSANNKGLANVDSNLEWVRLAQRVPVKIRLDRQMGDLYPAGTTATVVITGEQVNNDKKPSPLIRLLYRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CFT1_COCIM
Sequence: MQCYTELLPPSGVTHAISLPFLSATSNNLIVAKTSILQVFSLVNVAYGTSAPPNADDKGRVERQQYTKLILVAEYDLSGTITGLGRVKILDSRSGGEALLVSTRNAKLSLVEWDHERHGISTISIHYYEREDVHSSPWTPDLRLCPSLLAVDPSSRCAILNFGIHSVAILPFHQTGDDLVMDEFDEDLDEKPEGASNIPAQAAVANDTTMYKTPYASSFVLPLTALDPALVHPIHLAFLYEYREPTFGILYSHLTTSSALLHDRKDIVSYAVFTLDIQQRASTTLITVSRLPSDLWKVVPLPPPIGGALLIGSNELIHVDQAGKTNAVGINEFARQASAFSMVDQSDLGLRLEGCVVEQLGTDSGDILLVLADGKMAILRLKVDGRSVSGISAQLVSEKAGGSILKARPSCSASLGRGKVFFGSEETDSLLIGWSRPSQSMRKPKVESADDVFGDHSETEDDEDDIYEDDLYSTPVNQTTLSKTTSQTNGLNKDDFVFRSHDRLWNLGPMSDVTLGRPPGSHDKNRKQSSSRTSADLELVVTQGKGNAGGLAVLQRELDPYVIDSMKMDNVDGVWSIQVGAPDSTNTRTSSRNYDKYLVFSKSTEPGKEQSVVYSVGGSGIEEMKAPEFNPNEDSTVDIGTLAGGTRVVQVLKSEVRSYDTNLELAQIYPIWDEDTSDELSVVSASFAEPYVLIVRDDQSLLLLQADKSGDLDEVNIDGILSSHRWLSGCLYLDKYHTFVPTKGQDQPLSDNILLVLLRADHTLFIFSLPTLTEPLCSVDGVDLLPLILSCEPPPKRVTYRETLSEVLIADLGDSISRQPYMILRTANDDLILYQPYHPKTSLDKPELRFVKIIDHFLPRFDPSPKAYMPHSKFLRAYSDICGYKTVFMSGSNPCFVMKSSTSSPHVLRLRGEAVSSLSSFHIPACEKGFAYVDASNMVRMCRLPSNTRFDNSWVTRKVHVGDQIDCVEYFAHSEIYALGSSHKVDFKLPEDDEIHPEWRSEVISFMPQLERGCIKLLSPRTWSVVDSYELGDAERVMCMKTINMEISEITHEMKDMLVVGTATVRGEDITPRGSIYVFEIIEVAPDPDRPETNRKLKIFAKDDVKGAVTAVSGIGGQGFLIMAQGQKCMVRGLKEDGSLLPVAFMDMQCYVKVLKELQGTGLCIMGDALKGIWFAGYSEEPYRLTLFGKDNEYLQVIAADFLPDGKRLYILVADDDCTIHVLEYDPEDPTSSKGDRLLHRSSFHTGHFTSTMTLLPEHSSSPSADDPEEDDMDVDYVPKSYQVLVTSQEGSIGVVTPLTEDSYRRLSALQSQLVTSMEHPCGLNPKAYRAVESDGFGGRGIVDGNLLLRWLDMGVQRKAEIAGRVGADIESIRVDLETISGGLDFL
What is the function of this protein?
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.  Involved in poly(A) site recognition.  May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).
What are the official names of this protein?
Protein CFT1, Cleavage factor two protein 1.
What is the protein family that this protein belongs to?
Belongs to the CFT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATC5_YEAST
Sequence: MSGTFHGDGHAPMSPFEDTFQFEDNSSNEDTHIAPTHFDDGATSNKYSRPQVSFNDETPKNKREDAEEFTFNDDTEYDNHSFQPTPKLNNGSGTFDDVELDNDSGEPHTNYDGMKRFRMGTKRNKKGNPIMGRSKTLKWARKNIPNPFEDFTKDDIDPGAINRAQELRTVYYNMPLPKDMIDEEGNPIMQYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNNTKTHILEGVENENVSTDNISLWRRFKKANSRLLFKFIQYCKEHLTEEGKKKRMQRKRHELRVQKTVGTSGPRSSLDSIDSYRVSADYGRPSLDYDNLEQGAGEANIVDRSLPPRTDCKFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRTSKDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVYYDKKGRSRFSYEFGTIAGSAATNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGIDVETEGRREKAEIAKDRDTMIDELRALSGNSQFYPEEVTFVSKEFVRDLKGASGEVQQRCCEHFMLALALCHSVLVEANPDNPKKLDLKAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQKEFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTGDDVKEFGSEPSEIVDALLSKYLKEYFNLTGSEEEIFEAKKDHEFPKGNYAIVIDGDALKLALYGEDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWFSGLFIALSCLVVFAWTGIWSSAIASREFFKAAARIYGAPSFWAVFFVAVLFCLLPRFTYDSFQKFFYPTDVEIVREMWQHGHFDHYPPGYDPTDPNRPKVTKAGQHGEKIIEGIALSDNLGGSNYSRDSVVTEEIPMTFMHGEDGSPSGYQKQETWMTSPKETQDLLQSPQFQQAQTFGRGPSTNVRSSLDRTREQMIATNQLDNRYSVERARTSLDLPGVTNAASLIGTQQNN
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of phospholipids.
What are the official names of this protein?
Phospholipid-transporting ATPase DNF1, Flippase DNF1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein: KDPA_CAUVN
Sequence: MTWQGWAEIALTLSLAVAIGWPLGVFLSRVWNGEKTFLDPVMRPVEGLFYKACGVDPSKSQSWHAYALALLAFNLIGFVFVYAVLRLQGVLPLNPQGFPGLSGHLAFNTAISFITNTNWQSYAGETTMSTLSQMLVLTVQNFVSAATGATVAAALARAFVANRGEGVGNFWADLVRTTLYLLLPLAFVVAVVLAALGLPQTLAAGVTAHTLEGAEQKISLYAVASQEAIKMLGINGGGIFNANSAHPFENPTPLTNLITAISINTLGWAAFFAFGRTVLAKKDVRALVIAAFVLLFAGAVGVYATETQAPPAQVAAQVDTSANMEGKEVRFGAPATAAWVAMTTGASNGSVNGKHSSLMPLGGGIAMFLMQLGEILPGGIGSGVAIMVVMALLSVFVAGLMVGRTPEYLGKKVEAREIQFSILAVVIIPLSMLGFSGIAAVLPEALKGLMHSGPHGLSEILYAYVSGTANNGSAFAGLTANAPWWNVTLGIAMAMGRFMPIVAVLAIAGSLVTKPKLAPTAGTLPTDGGLFIGLLIGVILILGGLQFFPAMALGPIVEHFQALDAVAALR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TILS_PERMH
Sequence: MVEKKFLEAVKKYSLISEGDRILVAFSGGIDSTVLTYLLIKFRDHLKISDIYLAHLNHSLRKESDEDQRFCEDFAKKYGLEIFTKKVDIKSLAEKEKKSIEQKAREERYSFFRKVMEERSINRLATGHHLSDLVETMIMWFIQGNRKGIKGFRPKERDIIRPLYLINKDQIENYAREKGIEYRIDITNFETDFLRNRIRHNIIPHIKGINPSLEGSLLTLSYFLSLDDQYLEEESEKISQKFLNGKIELEELLVYDKALVYRAIQNWIYRKTGVYPSYRQIMDIMEIIEKKEGTKSIRLSPEYNLIRRYSTLYIEKVKEKTEPYQYRIKPGEKIFVKEANLYIKSYIETDYTLDKLKDERKKVCFQIESMEDAEFVVRNRRKGDRFIPFGRKKEKKLKDVMIDLKIPSDMRENIPLVVYGNKILWIAGYKRSAYFPVTEKGKKLICFELEEV
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE12_PSYCK
Sequence: MGVVDPKTSQNTSKKRIDRRIYAEHFGPTTGDKVRLADTNLWLEVEYDLTSHIDHQPDIDSVNIGEEVKFGGGKVIRDGMGQSQLLGEQVADTIITNALIVDYSGIYKADIAIKEGRISGIGKAGNPDIQPNVTLPIGAATEIIAGEGKILTAGGIDSHIHFIAPQQCETALMSGVTTMLGGGTGPAEGTLATTCTPGAYHIHSMLKATDAIPMNIGFLGKGNVSLPAPIVEQIEAGAIGLKLHEDWGSTPKAIDNCLSVAEEYDVQVAIHTDTLNESGYLDSTLGAFKDRCIHTFHTEGAGGGHAPDILKAIGETNVLPSSTNPTRPFTINTIDEHLDMLMVCHHLSPAIAEDVAFAESRIRKETIAAEDILQDMGAISMMSSDSQAMGRVGEVIIRTWQTADKMKAQRGHLAPDQSAKTEQSLDNIMLSPTDSDSGNDNFRIKRYLAKYTINPAITHGISDEVGSLELGKWADLVLWSPAFFGVKPDLIIKGGLIAAAPMGDPNASISTPQPVHYRSMFGSFPKTVAQTCITFMSSAAIDKGVDRQLGLEKVIKAVHNIRKVRKQDMKFNSYCPQMEVNPETYEVYADGELLTCEPAEHLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha 2, Urea amidohydrolase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.