PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_OENOB
Sequence: MNDEDQKILDAKPIADEIDSELTLRPKYLREYIGQKEIKDQLSVYLKAAKQRDEALDHVLLFGPPGLGKTTLAIVIANEMGAKIKTTSGPAIEKTGDLVALLNELTAGDILFIDEIHRLPKSVEEVLYSAMEDFYVDIVVGQGETAHAIHFPLPPFTLIGATTRAGMLSAPLRDRFGIVAHMQFYPVSDLKLIAKRTAEIFDTSIAGSGAAELALRSRGTPRIVNRLLKRVRDFAQVAGKDTIDEQIVDNALNKLHVDARGLDETDLKYLNTLIHQYKGGPAGVNALASNIGEDSETVEEMVEPYLLQIGFIQRTPRGRQATQAAYEHLQIPYQTGLS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: Y809_METJA
Sequence: MVIIMPTTYELKIYGKVQHVGFRDRIENIGKGLGINGIIYNYKDGTVRILANFDDEEDKELFKKYIERLEKKDKLIEIEKIEEKRLNTYIEFPEGISRLSSDDILELNKKLDEGVKYIKLIFAELEEHKKVLLEIKDMHVKTVEILSEHTRILNEIKDTLKDIKDKL
What are the official names of this protein?
Acylphosphatase-like protein MJ0809.
Protein: RNC_SHIB3
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2126_SYNE7
Sequence: MRYFFWSLLAIAAVLPISIAQAGSVRIEQAPNLQMSGMSGGGRASDCGYIGNRPSEQVTISPQYVEQSGYLRISVTAAGNPTLLIEGPSGRFCSVGQGGRNPQHVGVWPAGVYNIYVGDRQGQSHPYQLNLSGR
What are the official names of this protein?
Uncharacterized protein Synpcc7942_2126, ORF134.
Protein: HIS2_STRSV
Sequence: MLETLYQEALKRKKEPKEGSYTSYLYDKGLDKILKKVGEEATEVVIAAKNADKNEMANETADLLYHLAVALVETGVSLEEVETVLQARQGKQSRIHDRPEIDHY
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CL190_DROME
Sequence: MSDDTSASGGTSAPFPSPVTADPEPGATASKLPGPIRSNIPTPATSGTGIPQPSKMKAPSSFGSTGSVSKIGRPCCNHTTPKSGPPPREATSMSRESDDNLSSINSAYTDNSSAVLTANTEQFIIGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRLTTYPLAGAQTPTSPLAKSSPDRSRTVSPTASIRSSMLRSPGIGGKNGMAVGDRVIVSSGFGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMRMNAQQRKSSTPVKPILATPKSQFSMQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDALKAKVQTLETLPMDFTKPHAFDALTKRKPAPRLFCDICDEFDQHDTEDCPIQGSEDQDYSTPSSESNNNEKERKLPAPRKYCDSCEVFGHDTSECADDETY
What is the function of this protein?
Together CLIP-190 and jar may coordinate the interaction between the actin and microtubule cytoskeleton.  May link endocytic vesicles to microtubules.  May play a role in formation of furrows during cellularization.
What are the official names of this protein?
Restin homolog, Cytoplasmic linker protein 190, Microtubule-binding protein 190, d-CLIP-190.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Microtubule-associated. Lva-CLIP- 190 complexes are found at the Golgi.
Protein: YSM3_CAEEL
Sequence: MSKIIGKIGRLPKTLYEHKKKTIFFSFLGYLGADWVYRWDRNQGIRKEYAKIAVKYGETTVSPETRPKRVFVLVNVEGNSRGCFDQFNKNALPLFHLAGVQVDVVKADNQAQLEALAGAVDTQEADILYVVGGDGTIGTVVTGIFRNREKAQLPVGFYPGGYDNLWLKRMLPSVFENSDDVRHACETAMAVIEDQKKSVYAFELTTEGSTLAPEYGLGDVSAGWFRQIEDTRKKFWYFSMAKRRWAYFWEMLKRGPAPIECHVEYEETCAGCEKCRPKPIIEAPQWRWWHVLTGTPKYKNNDGQKDYTGIINEKCGEKHELDTHGAEFLIENEQMSDYSQIRFRMGGTDIGRFGVISDGFKRCSEGIVGRSTDEKFYGTDFLANSVAFKISALPSYIHRLYISSNATPKDAELTDRQITIRGTQKKLDIFLPTSIRLEL
What are the official names of this protein?
Uncharacterized protein F52C9.3.
Protein: ULP1C_ARATH
Sequence: MKRQRAIELDRVKKTMLNIDWDDALGDEEVPELEIIATDKIPPREPTLSGYEPAVSVRSLRDNELDDHLKRQRSLLTRLGDKLADKGEKIRNRIGELEYEKQRRMFQQRTKMQDADNGCQILEKPKSSDVFMRASTASKDTSGQGTSGSKDVSRSTFAAHFSDNLKMGPQPVKLVNDKLQDLGRGSWISKANRDSIIEKNNVWRSLPRLSKCKVSLKNFYSESKDPKGDRRPNEAYGKGKPNESSPYLLVDDDDGDDDKVIGYETPRHWSLKASPLQSSSCRKKSDDKVINLDEDEPLSPMVVEEACELPEGLPEDIYYPSSDQSDGRDLVQVSLKDLKCLSPGEYLTSPVINFYIRYVQHHVFSADKTAANCHFFNTFFYKKLTEAVSYKGNDRDAYFVKFRRWWKGFDLFCKSYIFIPIHEDLHWSLVIICIPDKEDESGLTIIHLDSLGLHPRNLIFNNVKRFLREEWNYLNQDAPLDLPISAKVWRDLPNMINEAEVQVPQQKNDFDCGLFLLFFIRRFIEEAPQRLTLQDLKMIHKKWFKPEEASALRIKIWNILVDLFRKGNQTD
What is the function of this protein?
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins.  Cleaves precursors of SUM1 and SUM2, but not of SUM3 or SUM5.  Able to release SUM1 and SUM2 from conjugates, but unable to cleave SUM3.  Protease activity mainly directed at deconjugating SUM1 and SUM2 from their target proteins.  Regulates salt stress responses and flowering time.  Redundant with ULP1D.
What are the official names of this protein?
Ubiquitin-like-specific protease 1C, Protein OVERLY TOLERANT TO SALT 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: MSHD_RHOE4
Sequence: MGWTDSLPAGSAEQVSALLDRATEFDGKAPVSEQGRHAVAGRGAARHFVELDGDTVVGYAQLQAGSDEHPDMAELVVDPQARRRGIGTRLAAAVFDEGRPGTRVWAHGNVDAAVEFAKSLDLVSVRELLQLRRPLDAPQLPEIVVPEGVTMRTYRGPEDDSEILRVNNAAFSWHPEQGGWTQAEIDERTAEGWFDPAGLFMAFADTDPDTLLGFHWTKVHAPEGDDPELGEVYVVGIDPAAQGRGLGRVLTLAGMHYLRDRGLGTVLLYVEGDNTAALHTYERLGFDRFHVDMAYARAL
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: GATB_BORT9
Sequence: MEYKLLVGLEVHVQLGLKTKAFCGCKNDFGGIPNSRTCPTCLGLPGALPSINKELISSAILAGHATNSKIKNIIKFDRKHYAYPDLPKGYQISQNDAPICENGFIFIETCSGLKKINIIRIHMEEDSGKSLHLLESENRSYIDFNRSGAPLLEIVSNPDINNGEEAVAYLSALREIFRYLDLSDCNMENGSFRCDVNVNLLINENGVEYKTPISEIKNLNSFKSVKLAIDYEKSRQKEEWILHRRTFESVGKHTMGFDDKKGITVLQRSKETVADYRYIKDPDLPLIKLDDSYIESIKSNRMVELPFDTRVRLKEQYGLSDFDVVTLTADKNLVKYFEEAAIASSDPKRVANWILSEVLSVLNDREMNILDFNLPPSYISELVEFIVNDRVSGKIAKEIFLEMLERNVSSAIIINEKNLAQISDISFIESVVFEVLNENPKSIELYKKGKSHAIKFMMGQIMRKTSGRVNPVLANEILMNKLRDV
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: HISX_BUCBP
Sequence: MEVYIPIIYWKSCSEKEKREILFRPVVNDNSQIKEVVKEIITNVKNSGDKALYDYTKTFDKIRLESIQVSYGEIVDSDSFVNEEIQKSISVAKNNIKIFHEKQTHNVVNIEIQPGVFCRQIIRPIQSVGLYIPGGCAPLVSTVLMLAIPAKIVGCKNIILCSPPPITKEILYASKICGIHNIFQVGGAQAIAAMAFGTKTIPKVNKIFGPGNVYVTEAKLQINALLNDLSIDMLAGPSEILIIADFKANACIIASDFLSQMEHGIYSQAILVTPSYDLACNVIFEINIQLKNLSRKKVINKSLKYSRIIVTKTLLECFEISNLYAPEHLIIQCENSNRLLVYVINAGSIFLGRWSAVASGDYVTGTNHVLPTYGSAIVNSGLTVMDFQKIISVQKLDQQGLIDVSSSIISLSEVERMDAHTNSIKQRLIALQDVK
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: TYDC1_NARPS
Sequence: MGSLGSDNIAELEANGSAFNLNPLDPEEFRRQGHMVIDFLADYYQNVHKYPVRSQVEPGYLKKILPESAPNQPESLETILDDITNHIVPGITHWMSPNYFAYFPASGSTAGFLGEMLSTGFNAVCFNWMSSPAATELETIVTDWLGKLLALPEKFLFSGGGGGVLQGTTCEAILCTMTAARDKVLNKIGKDQIGKLVVYGSDQTHCALQKAAQIAGIHPANFRAVRTFKSDAFGLNPEELRKVVSADVEAGLVPLYLCPTVGTTSSTAVDQLRGLCSVAEEHEMWVHVDAAYAGSACICPEFRHFIDGVEGATSFSFNAHKWFFTNLDCCCLWVREPQALINALSTNPEYLRNKATESQKVVDYKDWQIALSRRFRAMKLWMVMRSYGVANLRNFLRSHVKMAKLFEGLVSADERFEIVVPRNFAMVCFRFNPTKKDRATGPELDRINEFNRRLLEEVNSTGRLYMTHAVIGGEYVMRFATGATLTEEKHVRCAWRAIQEHAAALMEKIYYKQRN
What is the function of this protein?
Catalyzes the decarboxylation of L-tyrosine to tyramine, which is converted to norbelladine, a precursor to all Amaryllidaceae alkaloids such as galanthamine, lycorine and haemanthamine, and including haemanthamine- and crinamine-type alkaloids, promising anticancer agents.
What are the official names of this protein?
Tyrosine decarboxylase 1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: YB223_YEAST
Sequence: MTGSVNGTATWVGLPAQPLRSRVKVRHVTFLVFANLRLW
What are the official names of this protein?
Putative uncharacterized protein YBR223W-A.
Protein: SURE_VIBC3
Sequence: MNKRAAIQRAKIKMKILLSNDDGVYAQGIHALADALRDLAEIVIVAPDRNRSGASNSLTLEHPLRVSQIAENTYSVQGTPTDCVHFALNELMKDALPDLVLSGINHGANLGDDVLYSGTVAAAMEGHFLGVQSIAFSLAGTTHFASAAHFVRQLVEQHLANPIPTNRLLNVNIPDRPLELIQGIEVTRLGARHHAESMIKQKDPRGHDIYWLGPPGKEQDAGPGTDFHAIERGWVSLTPLQVDLTAHESLRSMDHWLKEKVNG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_SYNP6
Sequence: MSDWQRRHILSLADFSPVEYEMVLRTAAGFAEVLQRRNKKVPTLQGQVVTTLFFEPSTRTRSSFELAAKRLSADTINFAASSSSLSKGETILDTARTYLAMGSDIMVVRHAQAGVPQAIAREMERLGTEVRVLNAGDGQHEHPSQALLDLFTICSVIQPEQPSLGAIAGKKIAIVGDILHSRVARSNIWSLTAAGAEVHLAAPPTLLPPEFAQFANTPIPGSGLPRQLQIHWQLESALENADFVMTLRLQQERMSQSLLPSLREYHREFGLTRDRLRVCQPSVKLLHPGPVNRGVELSSDLMEDESISLIQPQVTNGVAVRMALLYLIGAAVPAAIPA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TAGX_STAAM
Sequence: MRLTIIIPTCNNEATIRQLLISIESKEHYRILCIDGGSTDQTIPMIERLQRELKHISLIQLQNASIATCINKGLMDIKMTDPHDSDAFMVINPTSIVLPGKLDRLTAAFKNNDNIDMVIGQRAYNYHGEWKLKSADEFIKDNRIVTLTEQPDLLSMMSFDGKLFSAKFAELQCDETLANTYNHAILVKAMQKATDIHLVSQMIVGDNDIDTHATSNDEDFNRYIIEIMKIRQRVMEMLLLPEQRLLYSDMVDRILFNNSLKYYMNEHPAVTHTTIQLVKDYIMSMQHSDYVSQNMFDIINTVEFIGENWDREIYELWRQTLIQVGINRPTYKKFLIQLKGRKFAHRTKSMLKR
What are the official names of this protein?
Putative glycosyltransferase TagX, Teichoic acid biosynthesis protein X.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: Y828_YERPY
Sequence: MSAVLSTENGLILKLYIQPKASRDQIVGLHGDELKVAITAPPVDGQANAHLVKFIAKQFRVAKSQVIIEKGELGRHKQIKVINPQQIPPEVTILLE
What are the official names of this protein?
UPF0235 protein YPK_0828.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: VPR_HV1V9
Sequence: MEQAPEDQGPQREPHNEWTLELLEELKSEAVRHYPRPWLHDLGQHIYNTYGDTWEGVEAIIRTLQQLLFAHFRIGCQHSRIGITRQRRVRNGPSRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: DPPA4_RAT
Sequence: MEPSGSKKGRAEEPREEVECQMSSQPSTSSAKTKATGKKQRKSEKDDGCKPEEKSAQDPETPGHARRKVPVPPFPQHLPPVNLIHRDVLRAWCQEMKLSSKGQKLDAYKRLLARAFPDQMPELKNVPDSAKEARLKMPRKKMKTEPGEESQVTVPLEIVTVPEEQIPALVDPPVLYEEVSTTVVTTSASEAVLASWARIAANAKKLEAVPSNATSETYGSTGEMWCVVHGTSLPATSSGWVRLQFHAGQAWVPDKKGKAIALFLLPACTFPPPHLEDNMLCPKCVHKNKILTKSLEG
What is the function of this protein?
May be involved in the maintenance of active epigenetic status of target genes.  May inhibit differentiation of embryonic stem (ES) cells into a primitive ectoderm lineage (By similarity).
What are the official names of this protein?
Developmental pluripotency-associated protein 4.
What are the subcellular locations of this protein?
Nucleus. Note=Associated with transcriptionally active chromatin.
Protein: L2GL1_MOUSE
Sequence: MMKFRFRRQGADPQREKLKQELFAFHKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAATVTQMHFLPGQGRLLTLLDDSSLHLWEIIHHNGCAHLEEGLSFHPPSRPSFDNASFPASLTRVTVVLLVAGNTAALGTESGSIFFLDVATLALLEGQTLSPDVVLRSVPDDYRCGKALGPVESLQGHLQDPSKILIGYSRGLLVIWSQATQSVDNVFLGNQQLESLCWGRDGSSIISSHSDGSYAIWSTDTGSPPTLQPTVVTTPYGPFPCKAINKILWRSCESGDHFIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRVIDFFTVHSTQPEDECDNPQALAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVANVPSKLWARIVSAGEQQSPQPASSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCEHADSLAQAVEDDWPPFRKVGCFDPYSDDPRLGIQKVALCKYTAQMVVAGTAGQVLVLELSEVPAEHAVSVANVDLLQDREGFTWKGHERLNPHTGLLPWPAGFQPRMLIQCLPPAAVTAVTLHAEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRTPAASSKLQEANAQLAEQTCPHDLEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDATHHGPTMWAGTNSGSVFAYALEVPAATAGGEKRPEQAVEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVMSEDYAETCLACLTNLGDVHVFSVPGLRPQVHYSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDISWPQNATQPRLQESPKLSQANGTRDIILAPESCEGSPSSAHSKRADTMEPPEAALSPVSIDSAASGDTMLDTTGDVTVEYVKDFLG
What is the function of this protein?
Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity.  Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells.  Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane.
What are the official names of this protein?
Lethal(2) giant larvae protein homolog 1, LLGL, Mgl-1, Mlgl.
What is the protein family that this protein belongs to?
Belongs to the WD repeat L(2)GL family.
What are the subcellular locations of this protein?
Early endosome membrane. Golgi apparatus, trans-Golgi network membrane. Golgi apparatus membrane. Cell projection, axon. Cytoplasm, cytoskeleton. Note=Localized to the lateral membrane during the polarization and formation cell-cell contacts. Enriched in developing axons (By similarity).
Protein: RS6_PAEAT
Sequence: MRPYELMVIIDPEVEERTVESSLQKFLNVITTDGGTIEKVDIWGRRRLAYDIKKKSEGIYAVVNFTAAPATAKELDRQLSLNETIMRTKIIRPEDQKVVAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: NUSB_RHOPB
Sequence: MAEMKKTIDNKPAPKGEKKANRRGAARLAAVQALYQMDVGGAGLNDIFAEFESHWLGNEVEGDQYLPAEQAFFQDVVSGVVRDQAKLDPLIDVALAKGWPLARIDAILRAVMRAGAYELEHRKDVPARVVVSEYVDVANAFVEGEETGMVNAVLDQIARQFRADEFSRG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: DARG_MYCBP
Sequence: MITYGSGDLLRADTEALVNTVNCVGVMGKGIALQFKRRYPEMFTAYEKACKRGEVTIGKMFVVDTGQLDGPKHIINFPTKKHWRAPSKLAYIDAGLIDLIRVIRELNIASVAVPPLGVGNGGLDWEDVEQRLVSAFQQLPDVDAVIYPPSGGSRAIEGVEGLRMTWGRAVILEAMRRYLQQRRAMEPWEDPAGISHLEIQKLMYFANEADPDLALDFTPGRYGPYSERVRHLLQGMEGAFTVGLGDGTARVLANQPISLTTKGTDAITDYLATDAAADRVSAAVDTVLRVIEGFEGPYGVELLASTHWVATREGAKEPATAAAAVRKWTKRKGRIYSDDRIGVALDRILMTA
What is the function of this protein?
Antitoxin component of a hybrid type II/IV toxin-antitoxin (TA) system.  De-ADP-ribosylates DNA (probably) modified on thymidine by its cognate toxin DarT, which neutralizes the activity of cognate toxin DarT.
What are the official names of this protein?
DNA ADP-ribosyl glycohydrolase, DarG, Antitoxin DarG.
What is the protein family that this protein belongs to?
Belongs to the DarG ADP-ribosyl glycohydrolase family.
Protein: GLMM_PROM2
Sequence: MQSIFGTDGIRGRFNEEITYSLAYKVGYALGSTLEKEKPILIGRDTRISGDILLQAITRGLNESGKKFINLGICPTPAIPYLIKQENLSSGIMISASHNPPEYNGIKIFDHSGQKITKHFENKIQKLIEELNQNISVPRKVIPLNKNKDLMDIYIKSLIQTMGGENLSGLKIILDTCHGSATTCAKKIFQYLGADVKVINNSKNGLKINMNCGSTNLEPLKKALIESPAHMGFSFDGDADRVIGIDSKGNVLDGDHILFLWGRELMEQKILTNNLLISTQMANLGFEKAWEKIGGILYRTDVGDKYVRDAIKEKRAVLGGEQSGHILSKINNFSGDGILTALQICKYCKKKNINLNDWLKSSFEPFPQKLTNINLDFNINKLNPKTKILIDQTIENFQAIYSDNCRVYIRPSGTEPVMRVLVEAKNHDKVNSLSSEITKKLFSEINKIIN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: YIDD_BACC4
Sequence: MKQIFIGIIRFYQKFISPMTPPTCRFYPTCSHYGLEAFQKHGAFKGFWLTCKRILKCHPFHPGGFDPVPDKKDDKVNS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PA1_VESMG
Sequence: MNLKYLLLFFCLVQVLHYCYSHGDPSLSNELDRGLIPKCKLVPEQISFVLSTRENQNGVFLTLDNLSKGGILPKSDLSSIPVIFLIHGFISSANNSNYVDMTKALLEKNDCMVISIDWRDGACTHEFKILKFIGYPNAVKNTRAVGKYIADFTKLLMQKYKVSLANIRLIGHSLGAQIAGFAGKEYQKFKLGKYPEIIGLDPAGPLFKSNDCSERICETDAHYVQIIHTSNNLGTERTLGTVDFYVNNGYNQPGCYLSFLGEACSHTRAVKYFTECIRHECCLIGVPQSKNPQPVSKCTRKECVCIGLNAKTYPKTGSFYVPVESKAPYCNNKGKKI
What is the function of this protein?
Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity).  May act as an allergen and induce hemolytic activity (By similarity).  In vivo, induces dose-dependent platelet aggregation (nanomolar concentration) and induces thrombosis (PubMed:18023835).
What are the official names of this protein?
Probable phospholipase A1 magnifin, PLA1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_CLAMS
Sequence: MPTIQQLVRKGRTPKVVKTKAPALKANPQQRGVCTRVYTTTPKKPNSALRKVARVKLSNGQEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIVRGALDTQAVKNRKQARSRYGAKMEKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PSD_PSEA8
Sequence: MSFKDRLFICSQYLLPHHLLSRLIGFAADCRATWFKDRLIAWFARRYQVDMREAQVEDLQAYEHFNAFFTRALKDGARPLAQEPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAELAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVWAGLVTPPKRELKTFRYDEAARAPIRLEKGAELGRFKLGSTAIVLFGPQQVAFNDGLGAASPVRMGECLALPKQS
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRPF_AZOC5
Sequence: MAIEVKICGLSTAETLEAALAAGADLVGFVHFPKSPRHVPLEAAPALSRAVAGRAAKVLLLVDPDDATLAAAVAAFQPDIIQLHGKESPERVAAIRARTGRPVMKALPVSGPADLAVVPAYAAVADRLLFDAKPAPDDTLPGGNGRVFDWTLLAGLDPGRPVMLSGGLDAGNVSQALSVVRLDGVDVSSGVETAPGLKSPEKILAFVRAVKAAEAASRPSRLKKVEAP
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.