PharMolix/UniProtQA huggingface dataset:
Protein: YL294_MIMIV
Sequence: MNIAYKYIGYIYTTIMSNKITVNKDYTQATLNPSNTVDIGPRISNYQADYLFIHFDEIMRREIDRNPDIIYDNNFQEFMQYVSEYKRILVESRKHKLVPGLFGSTSEQFSCSTGSHIFTPEDRDKINEAIILGQLNPRKYLTENDLSLIGFNNHYIQECGNRLSHNFFEHVALPTQRVWNNYLLSKSIEPNASITINTYQKLHEDFQKSMADINDQVINGDYATRYNIIEQKISDTVNFLENLISASNTEENIINNTLDLSNYYERLVFGEPNVDPSLVIPKDTIDLVERDALKKQIKASINRYSKMSTSSVLASTYNVASEVQNIRNVGSLATNLLDTLNNANNIINPPQELYDLMSTKLYIDDNGNQVAKYLNDTASNKLIQNEIDKQNSYLEFIRTNETITSRGKLIPVNSANDPLSRLNRYSHKYTYVPIAQGGNNSKSTKYQFNKKSTQNITISQSGGRDIDVEKLLDSSKQASNVINQTISDIDQSRNFYTKQTELYFNNNNFVDIDNLNQRNQLLIEMINVLGIYNFLIGERSNNRSVFLSELDKRTKSFKQILDNYIKSVNSRIPPITDDKTIGQILANGFLSVSEIQNLITTSGLNINVEQIPEDAILNNATTAKLISTLIDKYSLSNMKSVVSDLRKILNVAPLGITYQTNPEDSYKQLSSFYSILKSLNTSLLSEYQNLSTNTQNFQSIRDLTGKILESNISTFNTFTKQLIESVRNFGSEIDGIQSIRKQILQSKRRLADIEFFTRESTYNLSPKSQSVSQQDADLLQSKNLGVAVMNHDLSSNEITDFYQNYVTNYLDKIAGASVNVVKHYSYDKDIKTINDNKNMFNNTYDNYNTLLETLQTSANTTRTLRNIVSNNTTINSDASFNSLARRIWDVINYFNGTFMPLNSDIMNKINIPGDLSEYLSKYLIVNPEIINNYLANSVNFDSTGKIQPTDKLSRKSQIDLLVKTIPFYIKGAQLSDTYTTSQYSPGIPNQTFIGEVQDRLNQLIANETDDNAYNLYNYVTTSRNIILPEARIVGEISDQLEDVYNSRFSTPTNRSEFQNSILSQLDTIIIGIYRQFYETLMYLYQLANNYILINNPHNPMYSSIQKDQHNLAALQQDIRIMNLSNNFAVNGRDIPDIVPKSTGGPINCRNPLINKRFNKTIHRRINCLGLMIIDYNNNIGSDLSTITQQYNTFYQNSVPLLNLLRDQTISGEQINAILDVNINALNLFVANPKLLPNSFTYGTRIQESNMITPNIINTFDINNLDPNKSVFNDYETTLSAYIPSFVNDIIDINGQYIEYTNVRYHLISVGSISLPNVKIQAGDTISIRNIDDIQMLIDIGNNVVDFTNRLYKSSKQISNLVVETVDTWGSSVLTDSDEFNLRRSKKFRLLQTLNTLRHIEDSIRSNRNITRLNQFLLEKEDPTNAVLIMSAISIVNNINLTDRLFNENVDKIWIFARKLVNVWYTIFSQILSLLVVNGVVPATTNLIRSLDPFMRRSNLFNIDNVIDNTPNTNNYVDAINNEFNTKISQINNDKNKYPINLDPSKSTGIPDQDKYIIDNPNIISFNHYYNNISDKSSRVYILMAIMNDEGYRNINKYLESISDHTEYLINLVDFSENYLDNNFIQKKLDDLPIIDPKITNLVNAQTNFKQAFMLELQLELQALGLDQLYGPIESLVNNGTNTIQTGLSNPKTITPVAILDPNRSIEIDNQVSLDIISSPRIFDPSEYLYLANEFITSRQSGRFFRLYLSDIYRVIFRSITNELDRTMNSINQDISATNVADLEEFRETYLNYITNKKFSTTLYLNPTDLSDSITAVPNDSNSPNIKAVLLLPNDYQTNSDRINTINDIFRTVSETIKPNIYELFETEISNYNKLIQADYTVRKLITDYKSDVQNKLDKLRNIRNVISQVMFDNYFKQYAFISNGNLMTLLENTIENYETIWQLIEQKIYSIVNKNNYHILTMSQINNYQAFKSAINKLINNQAIIKKFYKRMSFGLIEYYYDIMDSLVVCLESKNFEDMSDIEAYIYQYHYVQLKRCHALFRWIRQEYQRNKQAQDDVNSRNITPGTKYNRILDYKIELLKTTGDVNSVFLEFQGLRRYLDEYSAIAMDKVQLHLRINDFVSNSYNNELNTLSNGRDISYMLDTDPNSNEYKNRWDNKQLMFINQGNSNNLKINFDLLQKIYQFNNPSSPPRDFEAYYTATYRRMKNNQGIDFQRIYNTNVFPESDVISNYMSIAPNILNNKGTVIMTYGYSGVGKSASLFGRKMDLSRGVDKPSNGILQATLDQLTNVEIYFRVFEIYGLGTQYNYYWNPTENNNYQCYPDFYQCIIHHVLDTTDSTTLKTKDHLVFTNRHDMLAYIMDLQNPKNGTQFTINNKNDPNLSNKTTFFNTIGQMVKSTYSKITEDHYRNFTDFVDDIDRVRSDGIHIKKVFDHIVKQIKGTINNPISSRSILVYDFEINLDPGSSNPIFIPFLIYDLPGKEDISRTYVDTSITPAIQGSSIEKINLRRRVFKDIDPPSTTPGVHNKERKSTYVLNPLLIPVFDNNIQIITDILGEISSKNTMISRLDVNFEATIVTDILNFVVDNFGVDNKGENVPSVQYPMNSFYKNPGGITTLVQLLSDNELIDTYKSTRYADVLPLIIGKGILSVNIIAGNRTYNPNENIKEIKILIGVVIIGHLIKYRLFDVVVEIINRIVEGPGNPNQNDDGGWSVSKIYAFFEAYYINENVVGLLQYLITNVLNKSSNSSGILEQVSTINNNNIKDTISQSYRTANAYSIIKSQLRIYPKTPLPDDYNIKVNSNLLVSSDVLKTLEIKEFMDNNDIQPDGQFFTPKVTPITELARRMDNVISFENRSDYDNNRIFRSGSSNFNCYDSNDVNDKILINPRRAIFNTAPSTMTETNRPLLQDFIEPYEQKISFYYIFYVVSNSQSRNKAEEQVKLLNNSMPFIDKMDPVSKKKQCV
What are the official names of this protein?
Uncharacterized protein L294.
What are the subcellular locations of this protein?
Virion.
Protein: RL2_OCEIH
Sequence: MAIKKFKPTSNGRRNMSVSDFAEITTDTPEKSLLSPIRKRGGRNNQGKLTVRHQGGGHKRQYRIIDFKRDKDGIPGRVATIEYDPNRSANIALVHYADGEKRYIIAPKGIKVGQEIESGENADIKLGNALPLGSIPVGTVIHNIELKPGRGGQIARSAGAEAQILGREEKYTLVRLSSGEVRLILTTCRATIGQVGNIEHELVRVGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPIGRKSPMSPWGKPTLGYKTRQRNKPSDKYIVRKRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RBFA_KLEP3
Sequence: MAKEFGRPQRVAQEMQKEIAIILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDKDEAAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHDDERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_SHEWM
Sequence: MTRLTQSDTWQALSTHTQSLPHMRDLFEGDAQRFKTMSTSACGLFLDYSKNRATEETLSLLFKLAEDAQLQSKIAGMFNGEIINTTEKRAVLHTALRASPEQEILLDGVNIVQEVQETQQKMAEFVNAITSGQWKGYTGKRITDVVSIGIGGSFLGPKIVSQALRPYWTGELNCHFVANVDATSICEKLKTLDAETTLFIMSSKSFGTQETLTNTLSAKDWFLKQGGSQLDVAKHFVAVTSNVPKATEFGIDAENIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFKALLQGAHEMDKHFLEAPLTENMPVIMGLFSLLYGNFHGAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLDGTDVDFSTGPVIWGGEGTNGQHAYHQLIHQGTALIPADFIMPLQSHNPLGEHHIQLASNCFGQTQALMQGRNYDEALNELSGSKLSADEQALIAKHKVMPGNKPSNTILMDKLTPSTLGSLIALYEHRTFVQGAIWDINSFDQWGVELGKSLGNDVLERLSADSDATSLDSSSNGLINMFRQGKI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_METPB
Sequence: MKFLDEAKVYVRSGDGGPGCVSFRREKFIEFGGPNGGDGGRGGDVWIECVQGLNTLIDYRYRQHFKARKGEHGMGSNCHGAKGDDAVLQVPAGTQVFAEDGETLIADMTEVGQRVRLAKGGNGGFGNAYFTTSTNRAPRHANPGQEGQEMWLILRLKLIADAGLVGLPNAGKSTFLATVTAAKPKIADYPFTTLHPGLGVVRSDAREFVLADIPGLIEGAHEGVGLGDRFLAHVERCRVLLHLVEGTSEHAGKAYKLVRRELEAYGGGLADKPEIVALSKADALDPDTLKNQVARLKRAAGGKPLVLSAASGQGVQEALRAIQAQLDGEDAADETAEPAEPWHP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YYDC_BACSU
Sequence: MIDLKIETAENILKYSYVLLENEFKNIQIGNDLIPLVNNSPLKKEKAERPEMNHFLLTKYNAVEENILYSSKILYELLEKEKHIDQLFLDYAKSQGIIINLNIERILYLSLTFLYSLGKVSFNQNMISRTES
What are the official names of this protein?
Uncharacterized protein YydC.
Protein: DOTZ_LEGPH
Sequence: MDEIKKDDELSQWLSTYGTITAERILGRYNISLPQDEILEAINIPSSFYRHLLQIPLKNVLNGIVIQQASDYHVYAQKLLIDYLLSGESSKEPDSQGAGTRESLEDERQRLVQLGDEFHKLELEQDNLIASSQASLMKISIDWNTKLETTLSKLNSLYKNTNSKIKKNAIRKALIKAFIHCDLVKDQSQKNKYQLIDKLNQTLAVSVGAELKESILTNLSELFQILEALNTKLDEFTDRTNHLSQQAKSFRTQFYEVILRIIELIKLLPEYKIDPAQDAINREPLYFDRTIGER
What is the function of this protein?
Component of the Dot/Icm type IVB secretion system (T4BSS), which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:32513920).  Part of a subcomplex which recruits effector proteins and delivers them to the core transmembrane subcomplex (PubMed:32513920).  DotY and DotZ play a role in effector translocation, but are not essential and do not influence the stability of the subcomplex main components (PubMed:34816517).  The DotY/DotZ main function is to optimize secretion by modulating the delivery trajectory of the IcmSW module and the localization of the machinery to the poles (PubMed:34816517).
What are the official names of this protein?
Type 4 apparatus protein DotZ.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the poles of the cell. Localization depends on the fully assembled T4CC subcomplex.
Protein: FLIG_BUCAP
Sequence: MTLNGTEKSAILLMSIGADQASEVLKHLTPFEVQELVASMVNINQFSNTILNTVLSECYDLFSKKNNLICNNDENYISDVLTKTLGEKQGRILLNEVLETRNVKMCIETFNHMDPEKFISLLDQEHPQILTTILMYLDKRQSSKVLSRLSEKKCTEIVLRMAEFNCIKESNLIDLKKIIENLLKRKKLIFSEKNGIKTVAEILNSMKIEDEQNILKKINVLNKNLTRKIIKEMFLFDNIVNIEDKYIQCLISNLEKEKLCIALQGTSEVIRNKFFKNMNEEEANKLSIYLEEKSYISDIAIKNEQKLILIMLKNILDNGIFSLKKLGKYYV
What is the function of this protein?
FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body.  This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
What are the official names of this protein?
Flagellar motor switch protein FliG.
What is the protein family that this protein belongs to?
Belongs to the FliG family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Bacterial flagellum basal body.
Protein: HDFR_ECO45
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDVHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFCSQLLGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: MUTS_YERPS
Sequence: MKNNDKLDSHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYSDAKRASQLLDISLTKRGASAGEPIPMAGVPYHSIENYLAKLVQLGESAAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDAKGFGYATLDISSGRFRVAEPADLETMAAELQRTNPAELLYPENFEPMSLIEHRHGLRRRPLWEFELDTAKQQLNLQFGTRDLIGFGVEQAHLALRAAGCLLQYVKDTQRTSLPHIRGLTMERQQDGIIMDAATRRNLELTQNLSGGSENTLAAILDCSVTPMGSRMLKRWLHMPIRDIRVLTDRQQAIGGLQDIAAELQTPLRQVGDLERILARLALRTARPRDLARMRHAFQQLPEIHRLLQPIDVPHVQNLLSQVGQFDELQDLLERAIVETPPVLVRDGGVIASGYNAELDEWRALADGATDYLDRLEIREREKLGLDTLKVGFNGVHGYYIQVSRGQSHLVPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALAIEKGLYEEIFDLLLPHLPELQLSANALAELDVLANLAERAETLNYSCPTLSDKPGIKIMGGRHPVVEQVLKEPFISNPLTLSPQRRMLIITGPNMGGKSTYMRQTALIVLLAHLGSYVPADQATIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEQSLVLMDEIGRGTSTYDGLSLAWACAENLASRIKAMTLFATHYFELTTLPEKMEGVANVHLDALEHGETIAFMHSVQEGAASKSYGLAVAALAGVPRDVIKRARQKLKELESLSNNAAASTIDGSQMTLLNEEIPPAVEALEALDPDSLSPRQALEWIYRLKNMV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: ASSY_YERE8
Sequence: MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYDAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVSVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSAQRWVASEITGEVTLELRRGNDYSILNTVSENLTYQPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTRKKLFSYATTGLLSASAEVGLPQVDNNNLTARGLQDKSK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM1_EBVB9
Sequence: MSGLLAAAYSQVYALAVELSVCTRLDPRSLDVAAVVRNAGLLAELEAILLPRLRRQNDRACSALSLELVHLLENSREASAALLAPGRKGTRVPPLRTPSVAYSVEFYGGHKVDVSLCLINDIEILMKRINSVFYCMSHTMGLESLERALDLLGRFRGVSPIPDPRLYITSVPCWRCVGELMVLPNHGNPSTAEGTHVSCNHLAVPVNPEPVSGLFENEVRQAGLGHLLEAEEKARPGGPEEGAVPGPGRPEAEGATRALDTYNVFSTVPPEVAELSELLYWNSGGHAIGATGQGEGGGHSRLSALFARERRLALVRGACEEALAGARLTHLFDAVAPGATERLFCGGVYSSSGDAVEALKADCAAAFTAHPQYRAILQKRNELYTRLNRAMQRLGRGEEEASRESPEVPRPAGAREPGPSGALSDALKRKEQYLRQVATEGLAKLQSCLAQQSETLTETLCLRVWGDVVYWELARMRNHFLYRRAFVSGPWEDRRAGEGAAFENSKYIKTHLFTQTLSSEHLHALTHSLYTFITGPLAEESGLFPPPSNVALARCCDAAGTLPHQKAFLTSLIWPGIEPSDWIETSFNSFYSVPGGSLASSQQILCRALREAVLTVSLYNKTWGRSLILRRADAVSPGQALPPDGLYLTYDSDRPLILLYKGRGWVFKDLYALLYLHLQMRDDSA
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: YEJL_SHIBS
Sequence: MPQISRYSDEQVEQLLAELLNVLEKHKAPTDLSLMVLGNMVTNLINTSIAPAQRQAIANSFARALQSSINEDKAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: RS15_STRCO
Sequence: MSLDAAVKKQIITEFGTKEGDTGSPEVQVALLSRRISDLTEHLKTHKHDHHSRRGLLILVGQRRRLLQYLAKKDIQRFRALVERLGIRRGAAGAR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: YM141_YEAST
Sequence: MHNLHCLAMLIPLNISRHPFSATRLFINWSKCQLSQRMILLILIFATFQRQRDLIIPRFLLLIYSVIQCLFLHS
What are the official names of this protein?
Putative uncharacterized protein YMR141W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GPR75_MOUSE
Sequence: MNTSAPLQNVPNATLLNMPPLHGGNSTSLQEGLRDFIHTATLVTCTFLLAIIFCLGSYGNFIVFLSFFDPSFRKFRTNFDFMILNLSFCDLFICGVTAPMFTFVLFFSSASSIPDSFCFTFHLTSSGFVIMSLKMVAVIALHRLRMVMGKQPNCTASFSCILLLTLLLWATSFTLATLATLRTNKSHLCLPMSSLMDGEGKAILSLYVVDFTFCVAVVSVSYIMIAQTLRKNAQVKKCPPVITVDASRPQPFMGASVKGNGDPIQCTMPALYRNQNYNKLQHSQTHGYTKNINQMPIPSASRLQLVSAINFSTAKDSKAVVTCVVIVLSVLVCCLPLGISLVQMVLSDNGSFILYQFELFGFTLIFFKSGLNPFIYSRNSAGLRRKVLWCLRYTGLGFLCCKQKTRLRAMGKGNLEINRNKSSHHETNSAYMLSPKPQRKFVDQACGPSHSKESAASPKVSAGHQPCGQSSSTPINTRIEPYYSIYNSSPSQQESGPANLPPVNSFGFASSYIAMHYYTTNDLMQEYDSTSAKQIPIPSV
What is the function of this protein?
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES.  Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation.  Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases.  CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 75.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BETB_BURO1
Sequence: MSVYGLQRLYIGGGYVDATSGKTFDTFDPATGELLAQVQQASAADVDRAVASAQEGQREWAAMTAMQRSRILRRAVELLRERNDELAAIETRDTGKPIGETLAVDIVTGADVIEYYAGLATAIEGLQVPLRAESFVYTRREPLGVCAGIGAWNYPIQIACWKTAPALAAGNAMVFKPSEVTPLTALKLAEIYTEAGVPAGVFNVVQGDGSVGALLTGHPDIAKVSFTGGVETGKKVMSLAGASSLKEVTMELGGKSPLIVFDDADLDRAADIAVTANFFSSGQVCTNGTRVFVHRSIKDAFTQKVLERVKRIRVGKPTDADTNFGPLVSAAQLDKVLGFIESGKAEGAKLLAGGTRLTDGHFGSGQYVAPTVFGDCRDDMKIVREEIFGPVMSILEFESEDEVIARANDTHYGLAAGVVTENLSRAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGITTLEHYTRIKSVQVELGRYNPVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: DOCK4_MOUSE
Sequence: MWIPTEHEKYGVVIASFRGTVPYGLSLEIGDTVQILEKCDGWYRGFALKNPNIKGIFPSSYVHLKNACVKNKGQFEMVIPTEDSVITEMTSTLRDWGTMWKQLYVRNEGDLFHRLWHIMNEILDLRRQVLVGHLTHDRMKDVKRHITARLDWGNEQLGLDLVPRKEYAMVDPEDISITELYRLMEHRHRKKDTPVQASSHHLFVQMKSLMCSNLGEELEVIFSLFDSKENRPISERFFLRLNRNGLPKAPDKPERHCSLFVDLGSSELRKDIYITVHIIRIGRMGAGEKKNACSVQYRRPFGCAVLSIADLLTGETKDDLVLKVYMCNTESEWYQIHENIIKKLNARYNLTGSNAGLAVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSDIIMPGEMRNDLYITVERGEFEKGGKSVARNVEVTMFIVDSNGQPLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPVDKFRGSHIRFEFRHCSTKEKGEKKLFGFSFVPLMQEDGRTLPDGTHELIVHKCEENTNLQDTTRYLKLPFSKVIFLGNNNQTMKATKESFWITSFLCSTKLTQNGDMLDLLKWRTHPDKITGCLSKLKEIDGSEIVKFLQDTLDTLFGILDENSQKYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEAERQEHIQEVLKAQEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELLMSVRFFLSQESKGTGALSQSQAVFLSSFPAVYSELLKLFDVREVANLVQDTLGSLPTIMHVDDSLQAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHIHLQEQKDLIMCARILSNVFCLIKKNSSEKSVLEEIDVIVASLLDILLRTILEITSRPQASSSAMRLQFQDVTGEFVACLLSLLRQMTDRHYQQLLNSFSTKEELRDFLLQIFTVFRILIRPEMFPKDWTVMRLVANNVIITTVLYLSDALRKNFLNENFDYKIWDSYFYLAVIFINQLCLQLEMFTPSKKKKVLEKYGDMRVTMGCEIFSMWQNLGEHKLHFIPALIGPFLEVTLIPQPDLRNVMIPIFHDMMDWEQRRSGNFKQVEAKLIDKLDSLMSEGKGDETYRELFNSIIPLFGPYPSLLKKIERETWRESGVSLIATVTRLMERLLDYRDCMKIGEVDGKKIGCTVSLLNFYKTELNKEEMYIRYIHKLYDLHLKAQNFTEAAYTLLLYDELLEWSDRPLREFLTYPMQTEWQRKEHLHLTIIQNFDRGKCWENGIILCRKIAEQYESYYDYRNLSKMRMMEASLYDKIMDQQRLEPEFFRVGFYGKKFPFFLRNKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQHANQPDETIFQAEAQYLQIYAVTPIPESQEVLQREGVPDNIKSFYKVNHIWKFRYDRPFHKGAKDKENEFKSLWVERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQTRQMQNINPLTMCLNGVIDAAVNGGVSRYQEAFFVKDYILSHPEDGEKIARLRELMLEQAQILEFGLAVHEKFVPQDMRPLHKKLVDQFFVMKSSFGIQEFPACIQASPVHFPNGSPRVCRNSAPASMSPDGTRVIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITGQSESSDEVFNMQPSPSTSSLSSTHSASPNVTSSAPSSARASPLLSDKHKHSRENSCLSPRDRPCSAIYPTPVEPSQRMLFNHIGDGALPRSDPNLSAPEKAVNPTPSSWSLDSGKEAKNMSDSGKLISPPVPPRPTQTASPARHTTSVSPSPAGRSPLKGSVQSFTPSPVEYNSPGLSSNSPVLSGSYSSGISSLSRCSTSETSGFENQANEQSVPVPVPVPVPVPVPSFSGSEEPVRKESKTPPPYSVYERTLRRPVPLPHSLSIPVTSEPPALPPKPLAARSSHLENGTRRTEPGPRPRPLPRKVSQL
What is the function of this protein?
Has a higher guanine nucleotide exchange factor activity compared to other isoforms.
What are the official names of this protein?
Dedicator of cytokinesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the DOCK family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytosol. Note=Colocalizes with EPHA2, RHOG and CTTN/cortactin at the tip of protrusions in migrating cells.
Protein: CMAE_PSESG
Sequence: MHSLFTLNLDLERAGKVICAQSLPFDTARETLLLLSPVGTQCCYMKNAALFLISHFNLIILESDTWLAYANEAGVNPEEGVADFIRQFNAALPEPVRVDALVGYCSSAPLALLAANQGACRTLLLLNGAYFLKDDGVIKSQYERDVERMMQSIPQGNCAQVYEAVSLLHTQSTYTPSDYRYQQVRPLRELSAFRQYLTFLNNLASLELVRIAQAVKTPTLVWCGSQDRYTDTASSRYIAQLLPHSELVEDPDGQHHDFVDGHERLYLTMTRFLTRHKQRAIQ
What is the function of this protein?
Involved in the biosynthesis of the phytotoxin coronatine (COR).  Catalyzes the transfer of the aminoacyl group covalently attached to the pantetheinyl arm of CmaA to the holo-pantetheinyl arm of CmaD.  During the shuttling process, CmaE generates a covalent-aminoacyl-S-Cys enzyme intermediate by the action of its donor substrate L-aminoacyl-S-CmaA and delivers it to the sulfhydryl group attached to the phosphopantetheinyl arm on CmaD.
What are the official names of this protein?
L-allo-isoleucyltransferase, Aminoacyltransferase CmaE.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: RL18_MYCMM
Sequence: MAQTQADTAARKPVGQSVSATRRVSRLRRHARLRKRIAGTQQRPRLVVHRSARHIHVQLVNDANGTTVAAASSIETDVRGLDGDKKARSVRVGQLIAERAKAAGIDTVVFDRGGYTYGGRIAALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: LOL1_ORYSJ
Sequence: MVASRAPRSESPWLKKPMHGVSGSTAMASTPWSSMPPSSHSLGAQSQLVCSGCRNLLMYPAGATSICCAVCGTVTAVPAPEQKSSCNVHENKERLKGNTNGFRAPQRCARRVDGACTQVAREVHTEVALVIFTLLCVTLPGLLFSLG
What is the function of this protein?
Putative zinc finger that may be involved in programmed cell death and defense response.
What are the official names of this protein?
Protein LOL1, Protein LSD ONE LIKE 1, OsLOL1, Putative zinc finger LOL1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LDH_STRPF
Sequence: MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEKTQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRINKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFISVRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQPAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNRF_STRC0
Sequence: MALTKPDVDVLVVGGGLGGLSTALFLARRGARVLLVERHASTSVLPKAAGQNPRTMELFRFGGVADEILATDDIRGAQGDFTIKVVERVGGRVPAQLRESFEELVGATEQCTPMPWALAPQDRVEPVLVAHAAKHGAEIRFATELTSFQAGDDGVTARLRDLGTGAESTVSARYLVAADGPRSAIRESLGITRHGHGTLAHFMGVIFEADLTAVVPPGSTGWYYLQHPDFTGTFGPTDRPNRHTFYVRYDPERGERPEDYTPQRCTELIRLAVDAPGLVPDILDIQAWDMAAYIADRWREGPVLLVGDAAKVTPPTGGMGGNTAIGHGFDVAWKLAAVLRGEAGERLLDSYGADGSLVSRLVVDESLAIYAQRMAPHLLGSVPEERGTAQVVLGFRYRSTAVAAEDDDPEPTEDPRRPSGRPGFRAPHVWIEQDGTRRSTVELFGDCWVLLAAPEGGAWGQAAARAARIWASASTSISSAAMSPPPPAN
What is the function of this protein?
Involved in the biosynthesis of the anthracyclines carminomycin, rhodomycin, daunorubicin (daunomycin) and doxorubicin (adriamycin) which are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers.  Catalyzes the incorporation of a hydroxyl group at position C-11 of aklavinone, resulting in epsilon-rhodomycinone.
What are the official names of this protein?
Aklavinone 12-hydroxylase DnrF, Aklavinone 11-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PheA/TfdB FAD monooxygenase family.