PharMolix/UniProtQA huggingface dataset:
Protein: LON2_SORC5
Sequence: MPTGDPSSRTPPSPDADSVPILPLRNSVLFPMSVVPINVGRPRSVRLVEDLLGRERALVGVISQRSPDVDEPTFKELYSVGTVARVVKVIRLGPNNYSVVLNGLGRFRVKSAFSLEPYMRARIERIPESLVRDVELEALGAGLREATREVLGLMPNLPRDTAGILDNVREPGALADLIASNFPQAQASVGDKQEILEAFDVKARVRLVLAMVGRQLEVLRVKKEISSMVQEEMGKSQREYILRQQMKSIKEELGEGGDDDEIEELRERIRRAKVPAEVDKVVRKQLSRLRSMAQQSAEFNVTKTYLEWIADLPWSKTTVDKLSVESVRRCLDEDHLGLEKVKKRIVEYSAIRQLRTDKKGPILLFIGPPGVGKTSLGKSIARSMGRRYERIALGGVRDEAEIRGHRRTYVGALPGRILQALKKAGTKNPVLVLDEVDKMGVDLRGDPAAALLEVLDPEQNSTFQDHYLDLPFDLSQVMFLATANNWDGIPGPLVDRMEVIEVPGYTRTDKLGIAREFLVPKQLSAHGLTDERLEFTEPGIEAVVDHYTREAGVRGLERQIAAVCRATAVKVAEGNDVREVATPEHVEQVLGPHKHRPEIAERTLQPGVATGLAWTPAGGEILFIEATKMPGKGNVVLTGNMRNVMQESASTAVSFVRSKADRLHLDPEWLKEIDLHVHIPQHGTPKDGPSAGVTMFAAVASLLLGAPVRSDVAMTGEISLRGRVMPVGGVKEKLLAAHRAGIRHVLIPAKNRRDLEDVPQDVKDQIKITMVSSMEEILPLVLEPPRRAPAQSASPEELEEQAGV
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease 2, ATP-dependent protease La 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_PARBA
Sequence: MPRKFFVGGNFKMNGTAKSITHIITNLNSAKLDPSTEIVIAPPAIYLVLARQLANGQVAVSAQNVFDKPNGAFTGELSVEQLRDEKITWTLAGHSERRVLLREDDEFVARKTKAAINGGLNVILCIGESLEEREAGKTIDVVTRQLDAVAEEVSPAEWNKVVIAYEPIWAIGTGKVATTEQAQEVHASIRKWLNEKISPEAAENIRVIYGGSVTENNCRDLAAQPDVDGFLVGGASLKPAFVDIINARL
What are the official names of this protein?
Triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
Protein: RS12_YERPA
Sequence: MATINQLVRKPRSMKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQSRSKYGVKKPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: U605_DROME
Sequence: MDHAITPEPHLVPGYTGHCAQNRDRVGRTYGRQTHKLLIDPCIYHAPELIVAPIHAKRGLKDYPTEQELKILRTREGLVDSVYRHPILPGYAGFVPNKVSQIGKRYVAAASAGVARHETLMELYRCENRTLRHRDLLESGNGLFDRKINERLLPQTYYRSPLILVTGVSKGIKDETCPPKTEKLCYSKFTSPHFLEDEDADKFIINGYSGHIPMSVTRFGESNKVLTNRALCSFSDYMYKRKRDTWCCGQDLSRPSITCPPVGHFVVYHEDSGMVPNYAGHVPGETYKFGRTYAKTTYDAKRWLEVHKNLTVLPEVANLDYAY
What are the official names of this protein?
UPF0605 protein CG18335.
What is the protein family that this protein belongs to?
Belongs to the UPF0605 family.
Protein: TYDC2_ARATH
Sequence: MFKPQHMYDREFGTGNGYSNGNGYTNGNGHTNGNGNYNGNGHVNGNGKANGAKVVKMKPMDSELLREQGHIMVDFIADYYKNLQDSPQDFPVLSQVQPGYLRDMLPDSAPERPESLKELLDDVSKKIMPGITHWQSPSYFAYYASSTSVAGFLGEMLNAGLSVVGFTWLTSPAATELEIIVLDWLAKLLQLPDHFLSTGNGGGVIQGTGCEAVLVVVLAARDRILKKVGKTLLPQLVVYGSDQTHSSFRKACLIGGIHEENIRLLKTDSSTNYGMPPESLEEAISHDLAKGFIPFFICATVGTTSSAAVDPLVPLGNIAKKYGIWLHVDAAYAGNACICPEYRKFIDGIENADSFNMNAHKWLFANQTCSPLWVKDRYSLIDALKTNPEYLEFKVSKKDTVVNYKDWQISLSRRFRSLKLWMVLRLYGSENLRNFIRDHVNLAKHFEDYVAQDPSFEVVTTRYFSLVCFRLAPVDGDEDQCNERNRELLAAVNSTGKIFISHTALSGKFVLRFAVGAPLTEEKHVTEAWQIIQKHASKFTRNDHY
What is the function of this protein?
Converts tyrosine into tyramine, a precursor of isoquinoline alkaloids and various amides.
What are the official names of this protein?
Tyrosine decarboxylase 2, AtTYDC, TyrDC-like protein.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16A3_PSET1
Sequence: MKNLYTQLEQDNVPKTLTLLLQSIVGACTEIATRINHGALSDVLGSLPDHNVQGEVQKKLDVIANNILIESLKKNKQVRAVASEEVEDIILCNSFGKYLICFDPLDGSSNTDVNGSLGTIFSITSASAAQTEVSEEDFFSTGRSIIAAGYVLYGPSLMLALSTGSGTHIYTLDPSNNNFMLTHPNLNIPEDTNEFSFNLSNQFKWPENVQKYIVDLQLGTDGIRKKNFNMRWLGAMVGDMHRILCKGGIFGYPEEKNFKYGKLRLLYEANPIAFLVEQANGLASNGTTSILDTVPSSIHQRIPVFIGSKNEVLLIEKYALGK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 3, FBPase class 1 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADB_SHISS
Sequence: MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAKAVLRQAINGDLDWKAKRQPKLEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDIVVEAVVENPKVKKAVLAETEQKVRQDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: RECA_HELAH
Sequence: MAIDEDKQKAISLAIKQIDKVFGKGALVRLGDKQVEKIDSISTGSLGLDLALGIGGVPKGRIIEIYGPESSGKTTLSLHIIAECQKNGGVCAFIDAEHALDVHYAKRLGVDTENLLVSQPDTGEQALEILETITRSGGIDLVVVDSVAALTPKAEIDGDMGDQHVGLQARLMSHALRKITGVLHKMNTTLIFINQIRMKIGMMGYGSPETTTGGNALKFYASVRIDIRRIAALKQNEQHIGNRAKVKVVKNKVAPPFREAEFDIMFGEGISKEGEIIDYGVKLDIVDKSGAWLSYQDKKLGQGRENAKALLKEDKALANEIILKIKESIGSNEEIMPLPDEPLEEME
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_RALSO
Sequence: MSSEGLMVFTGNANPKLAEAVVKHLNIPLGKALVGRFSDGEVQVEIQENVRGKHVFILQSTCAPTNDNLMELMVMVDALKRASARRITAAIPYFGYARQDRRPRSARVAISAKVVANMLEVAGVERVLTMDLHADQIQGFFDIPVDNIYASPILLEDLRKKNYDNLLVVSPDVGGVVRARALAKQLGVDLAIIDKRRPKANVAEVMNIIGEVEGRNCVIMDDMIDTGGTLCKAAQVLKERGAKQVFSYCTHPVLSGGAAARIADSALDEVVVTDTIPLRDDAAQCGKIRQLSTAPLLAETFTRIVRGDSIMSLFAE
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_PROM5
Sequence: MSKERNNLLIAASGTGGHIFPALAVSKEVEKYWNMHWLGVEKRLDSKFVPRKYNLLTLNLETPQKSIFILFQYLKILYSTFNIIKILKEKKINLVFTTGGFISAPTILAAKLLNIPVIIHESNLIPGTVTKYFGFLCEFVLIGFKDTNAYLKNCKTIFTGTPLRPEFYKTNPLPEWVPRGKGPLLIVMGGSQGAKRINEIFYESLDLLIKQNFRIVHIVGEHNINIPRKIKSNNYVQKKFTNQIASLMQNCDLVISRSGAGTINELIQTKKPSILVPYPNSKNNHQEKNAIILSSIGGAILINQDKISKVFFQETLKRIFKVKKNKGKPTYEILDLMKENMKNLTSLKSTNKIKNLINYFLKEF
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACTG_HUMAN
Sequence: MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, cytoplasmic 2, Gamma-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NNRE_BORPE
Sequence: MDIERVEQVRAVERLAHRRGLALMPRAGLAAADFVAARLPAGAQVLALAGPGNNGGDALVAATLLQARGYRVAVVMPAGPARLPDDARRAWQDWCAAGGQASADLPAHAPALVIDGLFGIGLARPLDGAWQGLIDQVNAWRVPVLALDVPSGLSAASGQPLGDPPGRPVRATWTLSFIGVPAALRAPGAAAWCGEQYLSLLGLTPAFLAEAVGPCGQATATAARRSGP
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: GREA_HELHP
Sequence: MATEPMTNYGYEKLCAELKNLKEVERPRIVVEIDIARSHGDLKENAEYHAAREKQAFIEARINELGLMLANAQVIDPASLPHNKVSFGSSVKILNLDTDKEFVYTLVGSMESNPSKGLISVSSPIAKALMGKSEGDEVSITLPNGENEFEILEVFYKDIVFEG
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: UBID_SHEB8
Sequence: MSFKDLRSFIDHLEANGELKRISYPVDPHLEMTEIADRVLRAKGPALLFENPKDHHMPVLVNLFGTPKRVAMALGKDDPLALREVGELLAFLKEPEPPRGFKDAIAKIPMFKQALNMPPKTVRNPPCQQVIKTGDEVDLTQLPIQHCWPGDVAPLVTWGLTITKGPRKSRQNLGIYRQQLLGKNKLIMRWLSHRGGALDFADFKQQFPGERYPVVVALGADPVTILGAVTPVPDSMSEYAFAGLLRGERTEVCKALSCDLEVPATSEIILEGYIGPEELAEEGPYGDHTGYYNETDKFPVFTVTHITHRKDAIYHSTYTGRPPDEPAMLGVALNEVFVPILRKQYPEIVDFYLPPEGCSYRMAVISIRKQYPGHAKRVMMGAWSFLRQFMYTKFIVIVDEDVNCRDWQDVIWAITTRMDPKRDTVMIENTPIDYLDFASPVAGLGSKMGLDATNKWEGETNREWGTPIVMDPKVKQKIDSIWDELGIDDSPTL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MURC_STRPF
Sequence: MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSFISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFMPYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAPIYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANLFVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPSKEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKIIKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_MYCMM
Sequence: MKLAIVAGDGIGPEVVAQAVKVLDVVQPGVEKTNYDLGARRFHATGEILPDSVIAELREHDAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVKSPLALEPGNPEIDFVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVHKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDIITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAHLGLDDAASRVDRAVEGYLATRGNERLATAAVGERIAAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODC_PONAB
Sequence: MSAKPEVGLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQTERLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALTFTIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAKQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPTLEFLRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQENW
What is the function of this protein?
Transports dicarboxylates across the inner membranes of mitochondria by a counter-exchange mechanism.  Can transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate (2-aminohexanedioate), oxaloacetate, and citrate.  Plays a central role in catabolism of lysine, hydroxylysine, and tryptophan, by transporting common metabolite intermediates (such as 2-oxoadipate) into the mitochondria, where it is converted into acetyl-CoA and can enter the citric acid (TCA) cycle.
What are the official names of this protein?
Mitochondrial 2-oxodicarboxylate carrier, Solute carrier family 25 member 21.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PYRG_SYNAS
Sequence: MRTKYIFITGGVLSSLGKGLAAASIAAVLECRGLRVTNQKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFTSTRMGKSNNLTTGQVYFSVITKERRGDYLGKTVQVIPHITNEIKDYIRQSSEGFDVALIEIGGTVGDIESLPFLEAIRQFRNEVGKQNAIFIHLTWVPFIKTAGEVKTKPTQHSVKALREIGIQPDILLCRTEEFLSEDIKAKIALFCNVEEAAVFTAKDVSCIYEVPLIYHREGLDQKIVDLLNIWTGQPHLEAWENVVQKITSPSYEVNIAIVGKYVNLTDSYKSLNEALVHGGIGNDCQVNLRFVDSEKIEKDGLNHQLENVDGILVPGGFGNRGIEGMIQVIRYARENKVPFFGICLGMQMAVVEFARHVCGLEKANSSEFDENTPHPVIDLLPEQKAVQEMGASMRLGSYPCRLSDASLACEAYGEVEIGERHRHRYEFNRDYQERLEACGLRITGRSPDGRLVEIVEIKDHPWFLGCQFHPEFKSRPTEPHPLFQRFIEAALRYRKKRAEDQ
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TSAD_NITMU
Sequence: MLVLGIETSCDETGVALYHTQQGLLSHALYSQIEMHGEYGGVVPELASRDHIRRLLPLIRQIFAEAGVSLRDLDAIAYTQGPGLAGALLVGASVAAALGFALKVPVLGIHHLEGHLLSPLLSDPAPAFPFVALLVSGGHTQLMEVTGLGQYRLLGETVDDAAGEAFDKTAKLLGLGYPGGPALSRLADEFTRSGQSARFELPRPMLHSGDFNFSFSGLKTAVLTLVNKHEMTPQIRGAIAQAFQEAAVEVLTEKSLAALAKTGLTQLVVAGGVGANRQLRSNLDRRAGTIGATVYYPKLEFCTDNGAMIAFAGAMRLESGESESSRLGKFTINARWDLEMQEIGREA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM9_SCHPO
Sequence: MDRLNVKEQEHLTQVLEAKQLKEYLNMYSTLTQNCFSDCVQDFTSSKLSNKESECIAKCADKFLKHSERVGQRFAEFNAKYMGQ
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim9.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: RR12_GRATL
Sequence: MPTIQQLVRSERHKSSKKTKSPALKGCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNIQEHSVVLIRGGRVKDLPGVRYHIVRGILDASGVKDRKKSRSKYGAKQPKT
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LUXS_SALAR
Sequence: MPLLDSFAVDHTRMQAPAVRVAKTMNTPHGDTITVFDLRFCVPNKEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQIPELNVYQCGTWQMHSLNEAQEIARHILDCDIRVNNNTELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: GSA_NEIG2
Sequence: MNRNEILFDRAKAIIPGGVNSPVRAFGSVGGVPRFIKKAEGAYVWDENGTRYTDYVGSWGPAIVGHAHPEVVEAVREAALGGLSFGAPTEGEIAIAEQIAEIMPSVERLRLVSSGTEATMTAIRLARGFTGRDKIIKFEGCYHGHSDSLLVKAGSGLLTFGNPSSAGVPADFTKHTLVLEYNNIAQLEEAFAQSGDEIACVIVEPFVGNMNLVRPTEAFVKALRGLTEKHGAVLIYDEVMTGFRVALGGAQSLHGITPDLTTMGKVIGGGMPLAAFGGRKDIMECISPLAGVYQAGTLSGNPIAVAAGLKTLEIIQREGFYENLTALTQRLANGIAAAKAHGIEFAADSVGGMFGLYFAAHVPRNYADMARSNIDAFKRFFHGMLDRGIAFGPSAYEAGFVSAAHTPELIDETVAVAVEVFKAMAA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_LEPIC
Sequence: MKISVGNDIVENSRIRDLLEKHGDRFLKRVFSESEREYCSNRKDPIPHLSGRFCVKEAFIKAIEPGDHVILDMREIELFGKEFGKKELVLHGKSKELFLTKGYSGCSVSISHAENYSTAVVVLYKE
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_ECO57
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CH601_CERSP
Sequence: MAAKDVKFDTDARDRMLRGVNILADAVKVTLGPKGRNVVIDKSFGAPRITKDGVSVAKEIELSDKFENMGAQMVKEVASRTNDEAGDGTTTATVLAQAIIKEGLKAVAAGMNPMDLKRGIDLATSKVVEAIKAAARPVNDSHEVAQVGTISANGEAQIGRFIADAMQKVGNEGVITVEENKGLETEVEVVEGMQFDRGYLSPYFVTNADKMTAELDDVYILLHEKKLSSLQPMVPLLEAVIQSQKPLLIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLQDIAILTGGQVISEDLGMKLENVTIDMLGRAKKISINKDNTTIVDGNGDKAEIDARVAQIRNQIEETSSDYDREKLQERVAKLAGGVAVIRVGGMTEVEVKERKDRVDDALNATRAAVQEGIVVGGGVALIQGGKALDGLTGENPDQNAGITIVRRALEAPLRQIAQNAGVDGSVVAGKVRESNEKSFGFNAQTEEYGDMFKFGVIDPAKVVRTALEDAASVASLLITTEAMIADKPEPKSPAGGPGMGGMGGMDGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.