PharMolix/UniProtQA huggingface dataset:
Protein: YLAK_BACSU
Sequence: MSKIYVLDTNVLLQDPNAIFSFEENEVVIPAVVLEEVDSKKRYMDEVGRNARHVSKLIDALRQKGRLHEHVPLDTGGTLRIELNHRSFHQLQEIFIEKTNDNRILAVAKNLSLEEETKENGRPVILVSKDVLVRVKADAIGLLAEDFLNDRVVDNDEMYSGYKDLYISQQLFSSFYGKNQISVNDVKQHAFYPNQFALMKDELGGSSSAVGIADKTGTVLKRLVFDDEHIWGIRPKNVQQTMALELLLREDIPLVTLIGKAGTGKTLLALAAGLLQTEDLGIYKKLVVARPIVPVGKDIGYLPGEKEEKLKPWMQPIFDNLEFLFNAKKPGELDAILAGIGSIQVEALTYIRGRSIPDQFIIIDEAQNLTRHEVKTLLTRVGEGSKIVLMGDPEQIDHPYLDSLNNGLAYVVERFKGQPISGSVKLLKGERSGLAQLAADLL
What are the official names of this protein?
Uncharacterized protein YlaK.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PhoH family.
Protein: OBG_ACET2
Sequence: MFVDRARIYIKAGDGGDGAISFHREKYISKGGPDGGDGGKGGDVIFVVDEGLRTLQDFRYKTRYRAEDGQNGGSSNCSGRSGEDLIIKVPPGTLVKDEQTGRILADLVKPGKKVVIAKGGKGGAGNQHFATPTRQVPSFAKPGEPGEELWVILELKLLADVGLIGFPNVGKSTILSMVTAAQPKIANYHFTTINPNLGVVNIDAENAFVMADIPGLIEGAHQGVGLGHEFLKHIERTKLLIHVVDISGSEGRDPVQDFEVINEELKKYNPVLCERPQIIAANKMDVTGAEENLEKFRKVIEPRGYKIFPVSAASNKGLKELIYYAAQKLKELPDTVLVNDQDNEVVYTAVEEEPFNIRKENGVFVVEGSWVQRLVRSVNFDNYESLQYFQRAIRRKGIVDALESMGINEGDTVRMYDLEFEYFR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNC_XANCB
Sequence: MTRPQAILTDIEGTTSSISFVKDVLFPYARRAMPAYVREHGGHPQVRHWLNQVADEIGEDVPDEVLITTLQTWIDEDRKHTALKALQGMIWEDGYRTADFSAHIYADAAIQLQAWHAEGIPLYVYSSGSVPAQKLFFAHSDAGDLSGLVSDWFDTEVGPKRESSSYRRIAERIGVPAPEILFLSDVIEELDAAKRAGMRTALLDRLEDYPTPRSADDVGSHQRVESFTQLVL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: SYK_BUCAP
Sequence: MIKKTDLNNNIFQKEKQIRKEKLINMKKNGFSFPNSFKKNTNSIKIHQEYENKTINELKVLNVEVTIAGRMIQRRIMGKASFFTLQDMEGKIQIYTREKEITSDFYNNHFKKWDIGDILGIEGILFKTKTGELSIFSKKLKILTKSLRPLPDKFHGLSNQEKRYRKRYLDLISNNQLFNIFKNRSKIIRFIRNFMIENNFLEVETPMLHNIPGGANARPFITYHNEINEEMYLRIAPELYLKQLIVGGFERIFELNRNFRNEGVSARHNPEFTMMEAYIAYSNYEDMMNFTENLLKNIIKSICGKSEIKYNKYYLNFNIPFKKLTMKESILQFNSNICLSDLKNLQKIKKIANNIGIEIKDNWNIGYIENEIFEKTVEKNLIQPTFITEYPVEVSPLARRNDFNSNVTDRFELFIAGYEIGNGFSELNDSEDQKNRFLNQMKIAEKEKNKDMLYDENYIEALKYGLPPTSGLGIGIDRLIMILTNQISIRDVILFPTLRSFKK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPE_HUMAN
Sequence: MAGRGGSALLALCGALAACGWLLGAEAQEPGAPAAGMRRRRRLQQEDGISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSSPDDAIFQSLARAYSSFNPAMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISVEGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYSPAAGVDFELESFSERKEEEKEELMEWWKMMSETLNF
What is the function of this protein?
Sorting receptor that directs prohormones to the regulated secretory pathway.  Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
What are the official names of this protein?
Carboxypeptidase E, CPE, Carboxypeptidase H, CPH, Enkephalin convertase, Prohormone-processing carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions.
Protein: SSRP_MYXXD
Sequence: MTSGGKSKGVGSEPGVRVIAENRRARFDYTVDEKVEAGLALTGSEVKSLRDGIANLSDAYALPKGDELFLLNANIGSYKAASFFDHLPTRGRKLLMHRGEIDRWTAKVRERGYSIIPLVLYFRNGRAKVELGLCRGKTHEDRRHDIKERETKREMDRAMRRR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PSBX_PROM5
Sequence: MIQISDLLLIANVSPEVAGSSGFNMIASFFAAALLIVIPAATFLIFVSQNDSLDRTSATRRR
What is the function of this protein?
Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.
What are the official names of this protein?
Photosystem II reaction center X protein.
What is the protein family that this protein belongs to?
Belongs to the PsbX family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: COAD_LEPBP
Sequence: MKSIAVYPGSFDPFTNGHLDIIRRAHPLFEEIIIAVAINSKKTSLFSPEERVEMIGKVFHGWDKIKIDTFEGLTVDYCKEKNSRVILRGLRAVTDFDYEYAISLMNKKLAPEIETYFLMADNEYSFVSSTIVKEVARHGRAVSNQVPDVVGEALVKKFSV
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_TOLAT
Sequence: MINDNVHLGHRARKRFGQNFLHDQYTIDSIVSAIAPRQNDVMVEIGPGLGALTEPVCDQIDKLHVVELDRDLAARLREHPRLKDKLIVHEADAMKFNFDELAQPGRPLRIFGNLPYNISTPLIFHLLEKSQYITDMYFMLQKEVVERLAAGPNSKDYGRLTVMTQYYCQVMPVLEVGPHAFKPAPKVNSAVVRLAPWKKRPYEALNIADLQRVCQEGFGQRRKTIRNTFRSFITAEQLEEIDINPNLRPENLTLAQFVSIANWLTTHR
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXVE_VIPAP
Sequence: QVRPFLEVHERSACQARETLVSILQEYPDEISDIFRPSCVAVLRCSGCCTDESLKCTPVGKHTVDLQIMRVNPRTQSSKMEVMKFTEHTACECRPRRKQGEPDGPKEKPR
What is the function of this protein?
Snake venom VEGFs that may contribute to venom dispersion and prey subjugation by inducing vascular permeability and hypotension.  This protein induces an increase in capillary permeability after intradermal injection, as well as a drastic hypotensive effect after intravenous injection (PubMed:10512636).  The hypotension is mediated by nitric oxide (NO), which is produced by VEGF-activated endothelium NO synthase (PubMed:14600159).  Also induces angiogenesis in vitro, probably through VEGF receptor (KDR/VEGFR-2) signaling (PubMed:14600159).
What are the official names of this protein?
Snake venom vascular endothelial growth factor toxin HF, svVEGF, Heparin-binding dimeric hypotensive factor, Hypotensive factor, HF, VEGF-F.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family. Snake venom VEGF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CHS7_KLULA
Sequence: MSFGDFSKICQRTPLPLCSVVKSAKQMVLTNDTTIKNSRLDIIDLGIIPVCYARSIDVANTMIFEIGNAFINIVAFFLLIIIIYNVRRKVTAIGRSEYSYFFQTCLVLIIFTLIVDCGVSAPGSSAYPYLVSVQLGLAGACCWMLSVLGLLGFRLWEDGTFKSMLLLYGMSFGGFILNFVVSIVTFKEWIQRKSDMSTDTMGLFTVMYVINALALLIYIICLLIVSVKVLQNYWATGAILLGVFFFVAGQVLIYAFSNNICEGMNHYLDGMFFGSLCNLFAIMMLYKNWDMSTDDDLEFSVSIDSTEYSTFNSDIKL
What is the function of this protein?
Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
What are the official names of this protein?
Chitin synthase export chaperone.
What is the protein family that this protein belongs to?
Belongs to the CHS7 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SSRP_SYNS3
Sequence: MGKGGGKKSAAARAAANRLLADNRLARHQYEILETLETGIELLGTEVKSVRAGQANLRDGFCLIRRGELHLHNVHISPHTHASRYFNHDPLRVRRLLAHRREIDKLRGHLEQKGLTLIPLNLHLQGSWIKVTIGLGKGRKLHDKRAAAKDKQVKKETRDAIARY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: TF2B3_HALSA
Sequence: MERATREREKEQREQAQTNDEAQQCPECNSANVITDQSERVCEDCGLVLEDDQIDHGPEWRAFNSSERDQKSRVGAPTTKTMHDKGLTTQIDWKDKDAYGRSLDAKKRNQMNRLRKWQERIRTKDAGERNLQFALSEIDRMASALGVPRSVREVASVIYRRALKEDLIRGRSIEGVATACLYAACRQEGIPRTLEEVTEVARIDQKEIGRTYRYVAQELSLEIQPTDPKEYLPRFASDLELSEEVIAKAREIIDTSAEQGLLSGKSPSGFAAAAIYAASLLCNEKKTQREVANVANVTEVTIRNRYQEQIEAMGFGV
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB 3, TFIIB 3.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: CCD30_HUMAN
Sequence: MSQEKNEMFESEWSKEREREKQLASGLDTAEKALKVESEELQKSKSELICLYNEVHNLPGESESKDHFLIACDLLQRENSELETKVLKLSQEFAQLNHFTLGGKTAPSNLITSENTCKDPESNEPILETEIQSRKEETEELCPKLGERKQKEIPEESVKEGSFPREGQKEEGSQQNRDMKDEEKEQQLTMKPEEIVRLREELSHINQSLLQSQSSGDSSDDSGAQHPSSGEKLKYNQQGEVQQLHQNLHRLQILCNSAENELRYERGQNLDLKQHNSLLQEENIKIKIELKHAQQKLLDSTKMCSSLTAEYKHCQQKIKELELEVLKHTQSIKSQNNLQEKLVQEKSKVADAEEKILDLQRKLEHAHKVCLTDTCISEKQQLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENEKRKYDEHVKSNQELSEKLSKLQQEKEALREEYLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLTNEVELRDKRINQFEDEIGILQHKIEKEKAIQDQITAQNDTLLLEKRKLQEQVIEQEQLIHSNKWTISSIQSRVLYMDKENKQLQENSLRLTQQIGFLERIIRSIHIRRGENLKEFPVPKWWHRGKLASLPPTKKQKEIYSTEVFTSNNAELQHEDESVPEATEKWKHSEQMETTISDILESEVVNEILPLSNSSFSGKGLVESFASLQETEEIKSKEAMASSKSPEKSPENLVCSQNSEAGYINVASLKETHGIQEQDQKSEL
What are the official names of this protein?
Coiled-coil domain-containing protein 30, Prefoldin subunit 6-like protein.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: H1D_STRPU
Sequence: MADTDAAPAAPAPSTPKKAAKKKASKPKTPASHPKYSDMIASALESLKEKKGSSRQAILKYVKANFTVGDNANVHIKQALKRGVTSGQLRHVKGSGASGSFLLAEKTKTPKKAAAKKATPKKKPAAKKTKKPAAKKATKKPAKKPAAKKKVAKPAAKKAAKPVAKKATPKKKVVKKAAKGKGKKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1-delta.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CH601_BURP6
Sequence: MAAKDVVFGDSARAKMVEGVNILANAVKVTLGPKGRNVVLERSFGGPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKTSDNAGDGTTTATVLAQSIVREGMKYVASGMNPMDLKRGIDKAVAAAVEELKKISKPCTTNKEIAQVGAISANSDSSIGDRIAEAMDKVGKEGVITVEDGKSLADELDVVEGMQFDRGYLSPYFINNPDKQVAVLENPFVLLHDKKVSNIRDLLPVLEQVAKAGRPLLIIAEDVEGEALATLVVNNIRGILKTVAVKAPGFGDRRKAMLEDIAILTGGQVIAEETGLTLEKATLAELGQAKRIEVGKENTTIIDGAGEAVNIEARVKQIRTQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVPGGGVALIRARTAIAGLTGVNADQNAGIKIVLRAMEEPLRQIVTNGGEEASVVVAAVAAGKGNYGYNAATGEYVDMVEAGVVDPTKVTRTALQNAASVAGLLLTTDAAVAELPKEDAPMPGGMPGGMGGMGMDM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLP1_SCHPO
Sequence: MNAAEWVAELKRKSQIESFKEQKGLVYDDHIEKVLYSGSVNGTLLVIEGNSCSGKTELLYHLASNVLLRSSQELVLIVSSEWDWSIKRLTFILHERLISSRGVSQTCKCNCAVKLENESTVHLQNAAREDGTDEDINSNSVNDVSLSSGETMLQFPEHEEQHECNREMEQLYESASSTVYPCSFWEDAERKIDAQCAILWPMEFSGVVESIPQSTKDLLRIWKEAKIQMHEDFRCNKTEFNEACFDASSSRLGCILMDGLSTFYWQLRLERGYTQVYADLQNRLCTSSKLFGCPVVCTNWLLNNKQHLPIQCKRFRSERRANARFYLENCVSKLGETFYLSVKGVQTKTEMASPYSQQEMEKV
What is the function of this protein?
Required for normal levels of meiotic recombination.  Acts in the recombinational pathway of double-strand break (DSB) repair together with rhp51, rhp55 and rad22.  Required for the full extent of DNA recombination and cell survival under condition of a replication fork collapse.
What are the official names of this protein?
DNA repair protein rlp1, RecA-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RAD51 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ISPG_HELPY
Sequence: MLENRVKTKQIFIGGVAIGGDAPISTQSMTFSKTADIESTKNQIDRLKLAGADLVRVAVSNEKDALALKELKKVSPLPLIADIHFHYKFALIAAQSVDAIRINPGNIGSKEKIKAVVDACKEKNIPIRIGVNAGSLEKQFDQKYGPTPKGMVESALYNAKLLEDLDFTNFKISLKASDVIRTIEAYRMLRPLVIYPFHLGVTEAGNLFSSSIKSAMALGGLLMEGIGDTMRVSITGELENEIKVARAILRHSGRLKEGINWISCPTCGRIEANLVDMAIKVEKRLSHIKTPLDISVMGCVVNALGEAKHADMAIAFGNRSGLIIKEGKVIHKLAEKDLFETFVIEVENLAKEREKSLKD
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RL17_CLOB6
Sequence: MAGYRKLGRPTDQRKAMLRNLVTSFLKHGKIETTETRAKETRSIAEKMITLAKRGDLHARRQVLSFVTEETVVQRLFEEIAPKYAERNGGYTRIYKVGPRRGDGAEVVILELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RS11_DESPS
Sequence: MAVAKKRKVKKNIPEGIVYIYSTFNNTIVTISDKQGNVVSWCSAGVLGFKGSRKSTPFAAQNALADAAKKAADCGMRKVEVKVKGPGPGREAALRALVSTGFEVSRIYDVTPVPHNGCKPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SURE_XANC5
Sequence: MRVLVSNDDGVDAPGIQILAEALRHAGHEVMVVAPDRDRSGASNSLTLDVPIRTRRVDAQTCAVAGTPTDCVHLALTGMLDYDPDIVVSGINNSANLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTHNHQAHHYDTAARAAVEIVARLKADPLPADTILNVNVPDLAWSDVLGFEVTRLGNRHRSEPCVPQRDPRGRTVYWIGPAGPEQDAGAGTDFHAVRTGHISITPIHVDLTRYQALDTVAGWVGGLTAALDGPA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5HT1B_HUMAN
Sequence: MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD).  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling inhibits adenylate cyclase activity.  Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior.  Besides, plays a role in vasoconstriction of cerebral arteries.
What are the official names of this protein?
5-hydroxytryptamine receptor 1B, 5-HT-1B, 5-HT1B, S12, Serotonin 1D beta receptor, 5-HT-1D-beta, Serotonin receptor 1B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYC_PROM9
Sequence: MIKLFNTLSKRVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKVKYVQNFTDIDDKILKRAKEESSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNICSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNIQEQNINKQGRMANEENNKKQNPQDFALWKKAKNDEPFFDSPWGRGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENEIAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVNYRKPLDFTEEALRSAAEAWKNINLALSFMDLTKGAFRSIDKNESIEEEYKEKLSFELSQKKLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRIEGLKIDLNEKFFLLENFKTLEKLTEVLGLKKEVLVKERKITEEEISSLINERLKAKKGKNYAKADEIRNLLKEKGIELIDQSKEITTWIRV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXB_SPIBA
Sequence: LVIVGGGPGGLAAAIYAGRAGLTPVIFLGIETSSQLMTTTEVENYPGFKTIQGPDLVQNQVDQAEHCGAQLFYEDVTKIDATARPFKITHGYENEIMTCDALIFATGSTAQRLDVIGEKQFWQKGVSACAVCDSMMAKNKDTVVVGGGDVACEEASYLSNIASKVYLILRRDAFRASAAMVQRVKSNPKIEIIYNSAVQEIKGETRVNQILVKNLKSGDITPLKVEALFWCIGHTPQTRLLKGQVKMSENGYILVENQTQYTNVPGIFAAGDCCDWIYRQAIVAAGSGCKAALDAERWLASNGGH
What are the official names of this protein?
Thioredoxin reductase, L-TrxR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLR_ECOLI
Sequence: MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSLYAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK
What is the function of this protein?
Involved in the repression of the expression of the mannitol mtlADR operon (PubMed:8300537).  Does not bind the operator/promoter regulatory region of this operon (PubMed:19840941).  Therefore, seems to belong to a new class of transcription factors in bacteria that may regulate gene expression indirectly, perhaps as a part of a larger transcriptional complex.
What are the official names of this protein?
Mannitol operon repressor, Mannitol repressor protein.
What is the protein family that this protein belongs to?
Belongs to the MtlR/FumE family.
Protein: MINC_VIBVY
Sequence: MSHSPDLKGSSFTLSVLHLCNNSVDTAIEFVKEKVEQAPAFFAAAPVVINIANVEGDLDFVALKQGISQAGFIPVGITGAKDKRTQNLASDAGFAIMSASKSPTQAPAKMAPTKIVRTPIRSGQQIYAKDGDLVILNHVSAGAEVIADGSIHIHGTLRGRAIAGASGQKEARIICHDLQAELISIAGNYWLSDQIERQFWQQKVMLSLVDESLHLEALTQ
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: THNX_HORVU
Sequence: MATNKSIKSVVICVLILGLVLEQVQVEGKSCCKNTTGRNCYNACHFAGGSRPVCATACGCKIISGPTCPRDYPKLNLLPESGEPNATEYCTIGCRTSVCDNMDNVSRGQEMKFDMGLCSNACARFCNDGDVIQSVEA
What is the function of this protein?
Thionins are small plant proteins which are toxic to animal cells.  They seem to exert their toxic effect at the level of the cell membrane.  Their precise function is not known.
What are the official names of this protein?
Probable leaf thionin.
What is the protein family that this protein belongs to?
Belongs to the plant thionin (TC 1.C.44) family.
What are the subcellular locations of this protein?
Secreted.