PharMolix/UniProtQA huggingface dataset:
Protein: E4PD_SHIB3
Sequence: MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMATVAFR
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1013_CHLPB
Sequence: MKASDTGSAGVLAGKLSALLSYLRSFLPFMWKNFMQDRVLLSAGSLAFQTLLSLIPLMAVVLSVLSVSPVFETFKRYVDDFLFQNFVPASGSMIREYFWEFIGNTATVPTVGGIFLLIIALFLISTIDHTINQIWDVRAPRKILQGFTLYWTVLTLGPIIIGSGLVASSYVWYTVFTEGPFLELRTRILSYLPLVNSFLAFFLLYMLVPNHRVRFLHAVSGAFLATWLFELSKQWFSFYVKTFATFEHIYGALSVIPLLFFWIYLIWVVALSGAEFVYCLGAVRQEVKKERKEFSTLHGLWDVLAVMEQIWKGQQCGQYVRYKKHALSGKGIDAARVRSIVAVLKENRLIHVTEDGEFALHCDIHEVTLFDLYSILPPEILVGSDAAVSGKRFEQLYELEAAVAACLRESLDKPLALYIKQEEGLPE
What are the official names of this protein?
UPF0761 membrane protein Cphamn1_1013.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: URK_STAAE
Sequence: MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTFDERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITIDFKPKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERGRSMDSVINQYLSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQSLVSKQ
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_GLUDA
Sequence: MSVNEENGAGKDASRANAQWGGRFAGGPSAIMQDINASIGFDHVLWRQDIAGSLAHAAMLARTGIISADDEAAIRRGLTEIGAEIEAGRFDFSTALEDIHMNIEARLSDRIGEAGKRLHTARSRNDQVATDFRLWVRDAIDGLDAQAASLMRALCRRAEQHAADPMPGFTHLQTAQPVTFGHHLMAYVEMLGRDRGRLADARRRLNECPLGSAALAGTSFPIDRRMTAAALGFDRPTANSLDAVSDRDFALEYLSALSIMAMHLSRLSEEIVIWCSAPFAFVRLSDAFTTGSSIMPQKRNPDAAELVRAKIGRVTGALVGLLTVMKGLPLAYAKDMQEDKEPVFAATDAAALSLAACDGMIRDLTANTDRMRAYAGSGFSTATDLADWLVRVLKLPFRTAHHVTGRLVGLAESRGVDLSDLSLADMQAEEAGITQDIFSVLTVESSIASRTSEGGTAPDNVRAQAARWLAVLENGA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPT_YERPA
Sequence: MRYISLNTTIITTTETTGYGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: RF3_FRATO
Sequence: MSEYLQQIAKRRTFAIISHPDAGKTTITEKMLLFGNAIKTAGTVKAKKSGIHATSDWMEMEKQRGISITTSVMQFPYNGRIINLLDTPGHEDFSEDTYRTLTAVDSALMVVDAVKGVEDRTIKLMNVCRLRDTPIVTFMNKFDRDTRDPLELLDEVENILKIKCAPMNWPIGMGKYFKGVYDLYNDEVTLFETGHGHEIYPYKKIKGLANAKDSIGIDLYEDLEMEIDLVRGASHEFDEQEFLEGNLTPVYFGTALSNFGVKEMMDGFTRYAPAPQHREADQRVVAADEQKLTGFVFKIQANMDEKHRNRIAFFRICSGKYEKGMKIFHERTGKQMQISKALTFMAGEREQVEEGYAGDIIGLHNHGSIQIGDSFTQGEKLKFKGIPNFAPEIFKRVKLNDPLKMKALQKGLVQLSEEGATQVFKPFISNDLVLGAVGVLQFDVVAQRLASEYNVKCSYEGVNVTLARWIFCNDEKKLNDFKKKYEVNLAYDGAGYLTYLAPTGVNLQLAQEKNPDIIFSATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_BURO1
Sequence: MFLPQEFIRRKRDGQPLDRDDMAAFVRGVTDGSVTEGQVAAFAMAVYFNDLSTDERVALTLAQRDSGDVLDWRALDLGGPVIDKHSTGGVGDVVSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLSAIPGYDVMPDTDAFRRTVREVGVAIIGQTARLAPADKRIYAIRDVTATVESVAMITASILSKKLAAGLDGLVMDVKVGSGAFMPTAEKSAELARSIVDVGNGAGMKTTAILTDMNQSLAPCAGNALEVACAIDYLTGKSRPARLHDVTMALSAELLVTGGLARDAAHAREKLQQALDSGAAAERFARMVAALGGPADLLDAPARHLARAAVIVPVPAPVSGVVQRVDCRALGLAVVALGGGRTRAEDAIDVSVGLSALAEIGQRIEAGEPLGFVHARDEAAAAHAVDAIRRGYVLGETGEAPPTLYQRVD
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: TOACP_TITOB
Sequence: MKMKMIVVISILLIVFSLSSKAMSLEDEQESVQREEDDLLGFSEEDLKAIKEHRAKNAGRFDPAV
What is the function of this protein?
Helical wheel projections predict no hydrophobic face, suggesting a non-amphipathic peptide (Probable).  Does not show antifungal activity (PubMed:27917162).
What are the official names of this protein?
Peptide ToAcP.
What are the subcellular locations of this protein?
Secreted.
Protein: CHBG_YERE8
Sequence: MEKLLIVNADDFGLCKGQNYGIIEAFRHGIVSSTTAMMNCAEIYHAAELSKQNPALPVGMHFVLTYGRPLTAMQSLVDAKGELGKWLWARAEAGELNLDEIAQELTAQFNKFVAVFGRPPTHVDSHHHVHMLPQIYPLIESFAHEKSLPLRIDRHEAQQQGMVLNSPRSTEWFDAGFYGENLTEQSFLQLLAKADQNGINTIEVMCHPAFIDKILMTSGYCYPRLTELEILTSPALKQSIEQLGYRLGSYSDC
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VTS1_SCHPO
Sequence: MEVVEGRRKTCLDVVDSPSSRQKQTIAVSLVDGKNYPTRFLNSRTIDKLKQELNTSNLSTGEMSTNETLKNAQEVAGKLLSEENEDSISEHFDEYLGADKPGISFLTRLKTLESWFQSLSLQDRLTTLRTLLHHLPSQEISTLLSSSLTSSPSNSGLSLDKSLPSSPKGDSPSLSSSLPSLTTKSNLSGNLNMVTPASTQGPAFSSKHGFSNALSTASPIPVRTSSVSSTYLTQDREASSKNCLSKALAFSSIEPPASSASTSPRNTPTPSNNGTSINANVTSSLTSNSTGKTSKTTDLLIAASKKSLPSNSTPSKPNTSFFETPHNNIWDSRDRGAFSAPPAPFFPLGFSPHLNDESSRSRWSNISYSPPPPPPPPELLNHSPKSRPLGDKPYLFYRNNQIGPRTRTEGRSSITEGKPFLSSSLRFEHVPSANDLNSVVNARVEKSTGQPSTPLNRQHYFNELPHSTTPVTLPSLIHGSEIDRRRSGFCLNNFNSTPPFQPYHYEIGSGLPQQMHATNTILTNPIDPNSNISTPVGMHLCTLPYTYQPFSSVEKIETPPNNSKNQTYRRSSRGSNKTRKSISHSKNTDKHVGNELPQDIPSWLRSLRLHKYTNNLKDTDWDALVSLSDLDLQNRGIMALGARRKLLKSFQEVAPLVSSKKMNENLKAAKNQSSESLTSFKGHTDSEDLPSGSMSNEISSNSTKQDVSSSSMD
What is the function of this protein?
RNA-binding protein involved in post-transcriptional regulation through transcript degradation.
What are the official names of this protein?
RNA-binding protein vts1.
What is the protein family that this protein belongs to?
Belongs to the VTS1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, P-body.
Protein: DEF08_ARATH
Sequence: MKLSLRFLSVLLLIAFMVLATTAEVSPLDNKICKTRSDRFSGVCISTNNCAIICQQFEHFDGGHCEFDGAFRRCMCTKQC
What are the official names of this protein?
Defensin-like protein 8, Low-molecular-weight cysteine-rich protein 73, Protein LCR73.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: KSP1_YEAST
Sequence: MTLDYEIYKEGGILNNRYQKIEDISEGSYGYVSLAKDVREKRLVAVKYIFKLEDDGQYDGPQDDENDCDSSDCDDDEDTKVDTDRHENENGNASSNNGSSREKKHNLYKHKKSLISSKVKSRLSNNICLEAMYEVDIQTKIGRHQNIAALLDFFDSYIIMEYCSGGDLYEAIKADAVPKKTKSITHIITQIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLATTDKTSMDRNVGSERYMSPELFDSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFSIANQSDKSFCYFAANREALFDVFSTMAYDFFQVLRYSLTIDPANRDLKMMRTELQNLSEYTLDDEYYNNLDEGYEETMIDGLPPQPVPPSSAPVSLPTPISSSNKQHMPEFKKDFNFNNVNERKRSDVSQNQNVASGFFKKPSTQQQKFFNQGYNTTLSTHERAKSAPKFKFKKRNKYGRTDNQFSKPVNIEDRKKSKILKKSRKPLGIPTPNTHMNNFFHDYKARDEFNTRDFFTPPSVQHRYMEGFSNNNNKQYRQNRNYNNNNNNSNNNHGSNYNNFNNGNSYIKGWNKNFNKYRRPSSSSYTGKSPLSRYNMSYNHNNNSSINGYARRGSTTTVQHSPGAYIPPNARNHHVSPTNQFLRVPQSTAPDISTVLGGKPSYQEHYTQDSMDSEGDHDSDDVLFTLEEGDHDFVNGMDNLSINDHLPHTTVGSHNEVFVHASTNHNNNGNNNHIDTNSTTNQYHRQYIPPPLTTSLHINNNNNESNELPDLLKSPASSEAHLNLSSGPIDPILTGNIGNRYSHSSDSKELEQERRLSMEQKFKNGVYVPPHHRKSFNLGTQVPPMNMKTSNEATLSVSHNSVNFGGSYNSRRSSANESNPLHMNKALEKLSSSPGAKSSFVGFPKPLLPRNHSSTTIALQNEDVFADSNNDAIIFEDEEYEGESDKMAHGKMEGGDNESSSTSPDERQIFGPYEIYAQTFAGSTHDKKLGAGRKTSIQDEMVGSLEQYKNNWLILQQQD
What is the function of this protein?
May act on PRP20.
What are the official names of this protein?
Serine/threonine-protein kinase KSP1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NATD1_HUMAN
Sequence: MAHSAAAVPLGALEQGCPIRVEHDRRRRQFTVRLNGCHDRAVLLYEYVGKRIVDLQHTEVPDAYRGRGIAKHLAKAALDFVVEEDLKAHLTCWYIQKYVKENPLPQYLERLQP
What are the official names of this protein?
Protein NATD1, N-acetyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the NATD1 family.
Protein: TDA11_DEBHA
Sequence: MNGSTSSDAVDPGLCVTTPSPVKQTLTLGSDTFNKDDKQITPSIRRSNSTRSKGINFNVAISPLATGQTPPSSKGGHRKTASYDAKNLHLPQLAESSPSSTIPDSPIPTASEELKYDLPLPSTEQLMGLDIDDQLRLLALKEMSIVEIKDSIGNLTSKLQRNENELHSLREVIQRSLYKELNSSSSKSKKETSSNGFVTRPQRQNSNPREEAIASTKNRSRRRTLSSSSSGVPPVLSSQQLSQNTDKQSRRDSTLWSNLSKPLNLIQQFDSMLQHEFEKSMIPQKNQEGSDKTMDSHKSRHSEDSTSSLGSISSPLNSKSKSVTGKQSNDELDRYFAQQSTSGASKDKPDGVVPTESHMNSDDMIQAVSSSIWSFVNDVKTNVLSSLADEDVPESRSHVTKGPSGFSNSNDQKEINDLTVYNLDTGSTVSLDKNEDSDLDYTFVHNTANEDRAAVDHDKSKND
What are the official names of this protein?
Topoisomerase I damage affected protein 11.
What is the protein family that this protein belongs to?
Belongs to the TDA11 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_BRUA2
Sequence: MTIILKPGSVPLETLEKIYREGLPVRIDPAFHAGIEKAAARIAEIAAGDAPVYGINTGFGKLASIRIAAGDVATLQRNLILSHCCGVGEPLSENIVRLIMALKLVSLGRGASGVRLEVITLIEAMLEKGVIPMIPEKGSVGASGDLAPLAHMTAAMIGEGEAFYRGERLSGAKALGKAGLKPVVLAAKEGLALINGTQTSTALALAGLFRAHRAARTALITGALSTDAAMGSDAPFHEEIHQLRGHKGQIDAGRALRTLLEGSAIRRSHLEGDQRVQDPYCIRCQPQVDGACLDILRQAARTLEIEANAVTDNPLVLSDGRAVSGGNFHAEPVAFAADQIALAVCEIGAISQRRIALLVDPSLSFGLPAFLARKPGLNSGLMIAEVTSAALMSENKQMAHPASVDSTPTSANQEDHVSMACHGARRLLQMTANLNAIIGIEALTGALGVELRKPLTTSAELAKVIAALRAKVATLEEDRYMADDLKAAAELVADGTLSGVISAGILPDLEA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EVN_ARATH
Sequence: MKTTATSFVTGERVVVFVVVSRILLSLPLSLISHGFSLFLLSLSAFLVEIRVETSPFLLSHFSSRRGASSGILLGAVTLPSVMISKLVQLSRAISIHEAEQDELAHVTMQYWAASASCCAILIYLSVIMSQVRKDESLSSSSIWLTRVSLTGTVLYGVACFVSLSMISHTGLNTSLKMLWMLFHGLAAVKLIRHLLCTFPSCASIGEALLVTSGLVLYFGDFLACTIAKIFEKLIPVDLVSISYGIKRTETGIIVQGLLLGLLLFPMVFRFVLHIYESSLRKRDARQRNCSDAAKSVLFFVSLLFFMVVAVPSWMQFVHDFNQHPFLWVLTFVFSEPLKRLSLCIYWILLIVVSVSRFYNISRSSKVERILLRKYYHLMAVLMFLPALVLQPKFLDLAFGAALAVFVALEIIRIWRIQPLGEPLHQFMNAFTDHRDSEHLIVSHFSLLLGCALPIWMSSGFNDRALSPFAGILSLGIGDTMASMVGHKYGVLRWSKTGKKTVEGTAAGITSMMAVCFVLVPILASMGYILSQGWWSLLVAVTATGMLEAYTAQLDNAFIPLVFYSLLCL
What is the function of this protein?
Essential for pollen development.  Involved in protein N-glycosylation in the endoplasmic reticulum (ER), especially in the female gametophyte.  Mediates pollen tube (PT) reception in synergids through protein glycosylation.
What are the official names of this protein?
Dolichol kinase EVAN.
What is the protein family that this protein belongs to?
Belongs to the polyprenol kinase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL27_BIFLD
Sequence: MAHKKGASSSRNGRDSNPQYLGVKKFGGEAVVAGNIIVRQRGTNFHPGHNVGMGKDHTLFALTDGSVKFGVRRDRKVVDVIA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: MQO_ECO81
Sequence: MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRNDDNSWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDADKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: PAN2_YARLI
Sequence: MEGWQEPPRIPLTQICRVSHTAPVATEIGQLTDTLPLTFDLAEDLVWAGDTNGIVSSYYGETLQPYSRFRAGRGRVTSLVSHDRGLVALTTDALHYSTRGGLTRKHVTDPSLGNNLCMTFTHGPTEFVVGGNPGKLVVVNSERGDVTRVVDSPGMATHMAGSSSCVVWGTENGKLVVGDNNLKELHTFQAHQGPFSDVSVQDNVVMTCGFSAASTGHRIDPLIKVWDLRMMRAMAPISYPLAAFVCQTPDSRTLITSPSGQLEFLDHATQQIKLYQAEVALVNGVKLSPRGHHFVVSDTSGQLQLWSDEPQSSFAEFSAPTAFPTPEQSYPPVSIRDTRYPLGAVGMPYYSDTLLSAMPSSIINVGMPPEEVDEDLEVRQIDFVGHAPNYKQQKRNLAQKYSNQRRTSIAAPKFLSEKEKERARRMEDIEDESFFGDEDTCTEASMSSKKVPRLYRKLEIKYSKFGISDFDFSYYNNHTGLSGLETNPFNPLLQLFRFCSPVFNFALRSVARGTPNRLLNEVGLLFDMMHKARGHVCRASNLMHCYDGIAQTRSLAPEDATNIVLFCRFLLEQIGFEQRQTPALFDSFRQLLGATVITVNTFSCGKMAQAESVWYTLELALGSTFYECLERTLDKELHTRAWCDKCRKYQSLHVSKHVESLPQVLTLSVADGNVDVAKSFLVLDGKVSPAAETDNDAYKLVGFICQIQGNGQVAFIRVGDEWYLFNDFLVTKVSEKEAFMKTPWKRTVMMVYAVGADERFDYDSWKNDMDVSALFEERLVNGNNVSRETTDYGYELIKEVPPPKTLCAIDAEFVVLKNEETEIRSDGTKVVLAPRNLCLARVTLLNEDGHPFINDYIAINEHIVDYLTAFSGIEPGDLDPSISRKPLVSLPTSYRRLWLLLNLGCVFVGHGLANDFRTINMQVPPEQVIDTVDLYYIPSERRKLSLRFLAWCVLGKKVQSGNHDSTEDSHTALLLYKKYQDCAPEEFQVLLLDVYRQGRMCNFKVPEA
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_SYNFM
Sequence: MDKPLVIAGRSFQSRLLLGTGKFSSSEAMKRAIEASGSEVVTVALRRVELENPQDSILSAIDTSRYLLLPNTSGARDALEAVRLARLARAAGCEPWVKLEVTPDPHYLLPDPVETLKAAEILIKEGFIVLPYINADPILAKRLEDLGAATVMPLGSPIGSNRGIRTRDSIAIIIEKANVPVVVDAGLGAPSHAAEAMEMGADAVLVNTAIAVAGDPEAMAKAFRKGVEAGREAYLAGLGSTRATAEASSPLTGFLR
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_CAMJE
Sequence: MCGIVGYIGNNEKKQIILNGLKELEYRGYDSAGMAVMQEGELSFFKAVGKLENLANKCTDFESQGYGFAIGHTRWATHGKPTEINAHPHLGQYSCVIHNGIIENYKEIKDKLEKEGVSFLSQTDTEVIVQLFEFYARNLGVFEAWQKTIKELRGAFATLLVTKKDPNHVYFAKNAAPLIIGKNANKEWYFSSGDAPLIGSCDEVMYLEDLSLGYASKDELVVYENDILKSLCFSKLSGDKAYAKKDGFRFFMEKEIYEQSRVMSEVLMGRIQGDEVVFDELNNEDLSQVDEITLCACGTSYHAAMASAYLFERIAKVKAKVEIASEFRYREAIIKKDSLFIVISQSGETADTLEALKIAKEQGAKTFAICNVDNSNIVRLAHLSLLTRAGIEKGVASTKAFATQVLTLWMLAIFMAQKRNLNVSAEIKALLHTPNCVSVKQALHEKIHRLSKRYLDGHGFFFIGRDVFYPLALEGALKLKELSYLHAEGYPAGEMKHGPIALADSKLYTIALMPKHMLYEKTKSNVEELIARDSTVLSISPLEFDLSDDFIKTNEQDHYMCEFFEMMVITQLLAMEISIRLGNDVDMPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_MYCPA
Sequence: MTNSQSDAALAAVLDRFDPSAGGPGAYDTPLGITNPPIDELLDRVSSKYALVIYAAKRARQINDYYNQLGEGILEYVGPLVEPGLQEKPLSIALREIHGDLLEHTEGE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PFDA_SULIM
Sequence: MSQGQGGITLDDLIAQADYLKRYIDSLQRTQLELLESINSIDSAKQAIETIKSGNKEMLVFIDRKGYLLAKVGGIVGDKVTVHLGLSYYAEVDLDSAIKILDKRKDEISKAAQNLNNELQKAASTYNQIVDILNQIQQAAARRQQGE
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBAN_ANOGA
Sequence: MSRFYFFFNLICLYLAIKSALSAELDTNDQKYADLRTTGRGESPDSTGPDSDTLRRDDGAEGLNKRAAAMWFGPRLGKRTIAADLHDDLVEEFDAEPLGYAGEPPQKLATELVQGAPYMVLLVTAKPRKPQPIFYHTTSPRLGRRDSVGENHQRPPFAPRLGRNLPFSPRLGRSYNGGYPLPFQFAY
What is the function of this protein?
A hormone that controls sex pheromone production in females and pheromone responsiveness in male.  Also mediates visceral muscle contractile activity (myotropic activity) (By similarity).
What are the official names of this protein?
PBAN-type neuropeptides, Pheromone/pyrokinin biosynthesis-activating neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: COAD_XANC5
Sequence: MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALSLERRVALAQEALAAHTNVEVRGFDTLLAHFVREMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVEALRQVRQSRAQA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REL3_MOUSE
Sequence: MAMLGLLLLASWALLGALGLQAEARPAPYGVKLCGREFIRAVIFTCGGSRWRRADILAHESLGDFFADGEANTDHLASELDEAVGSSEWLALTKSPQAFYGGRASWQGSPGVVRGSRDVLAGLSSSCCEWGCSKSQISSLC
What is the function of this protein?
May play a role in neuropeptide signaling processes.  Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 (By similarity).
What are the official names of this protein?
Relaxin-3, Insulin-like peptide INSL7, Insulin-like peptide 7, Prorelaxin M3.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSTB_PARMW
Sequence: MTTSQLQTEQHQVSDDTAISIQNVTISYGSYEAVKNVYCDVPRGKVTAFIGPSGCGKSTVLRALNRMNDLIEGCSLKGRVLFDGVDLYGASVDPVEVRRRIGMVFQQPNPFPKSIYENIAFGARINGFTGDMDELVERSLRQAAVWDECKDKLNESGYSLSGGQQQRLCIARTIAIQPEVILMDEPCSALDPISTLKIEETMHELKKSFTIVIVTHNMQQAVRVSDMTAFYNAEAVEGGSGKVGYLVEFNETEKIFNSPQQQATQDYVSGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ILVD1_BRADU
Sequence: MPAYRSRTTTHGRNMAGARGLWRATGMKDADFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEQAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRELIADSVEYMANAHCADGLVCISNCDKITPGMLMAALRLNIPAVFVSGGPMEAGKVKLQGKTKAVDLIDAMVAAADSKVSDEDVKVIERSACPTCGSCSGMFTANSMNCLTEALGLALPGNGSVVATHADRKRLFVEAGHTIVDLVRRYYEQDDASVLPRNVANFKAFENAMTLDIAMGGSTNTVLHLLAAAHEGQVAFTMKDIDRLSRRVPVLCKVAPSVADVHVEDVHRAGGIMGILGELDRAGLIDTSVSTVHAPTMADALERWDIKRSKSEAVRTFYRASPGGIPTQVAFSQERRYDELDADREKGVVRDLEHAFSKDGGLAVLYGNLAQDGCIVKTAGVDASILKFSGPARVFESQDAAVEGILGGKVVAGEVVVIIYEGPRGGPGMQEMLYPTSYLKSMGLGKACALVTDGRFSGGSSGLSIGHLSPEAAEGGNIGLVRTGDLIAIDIPNRSITLEVSDEELAKRRASEEAKGDAAWQATGRKRNVSTALQAYAALTTSAARGAVREVKRRSN
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase 1, DAD 1.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.