PharMolix/UniProtQA huggingface dataset:
Protein: CE104_MOUSE
Sequence: MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPKFCQFPQEIVLQMVERCRVRKLQLLAHQYMISSKVEFYISESLPEYLVPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHANKYNIYNQVALVAINIIGDPADLGDESNITSREKLIDHYLGHSPHNPEDPALDGTFSGRSDYISPLDDLAFDMYQDPEVAQIIRRLDERKREAVKKERYDHAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMARYRAQVYEQLELHGLLQGEPEMQRPFALPLQPLASPSSPQHWKAVSSLPRTEKLVAEDSFAGPVLQEKPSASSPQHSAVDPSPPAAGHAPRSHTEVLPYDERPLPVTRKQLGEASAEAEVKEADSDVRRRGVAGEPEPLTEKALREASAAIDTLGEALVAGAYSKMWSCREDALLALYKKLMEMPVGTQKEDLKNMLRASVFLIRRAIKDIVASVFQASLKLLKMIITQYIPKHKLGKLDTTHCVERAFPLLLARAGDSSARLRVMALNFIQEMALFKEVKSLQLIPSYLVQPLKANASVHLAMSQVDLLARLLRDLGTESSGFTVDNVMKFAVSALEHRVYEVRETAVRIILDMYRQHPALTLEHLPPDDSATRRNLLYKAIFEGFAKIDGSVLPTEAEVRAQKRVATKEAEKQKKEEMKALQGQSGELRETQAGVQEKESEAVKLRNQDPQGRKAVLPDTPEIPANHFLDNLCIFCGERNESFTEEGLDLHYWKHCLMLTRCDHCRQVVEISSLTEHLLTECDRRDGFGKCPRCSEAIPKEELPGHIKTKECSPAKPEKVANHCPLCHENFAPGEEAWKVHLMGPAGCTMNLRKTHVLYKATAPQQGKGPAAAKSSTSAPKVGSKIPTPKGGLSKSSSRTYMRR
What is the function of this protein?
Required for ciliogenesis and for structural integrity at the ciliary tip.
What are the official names of this protein?
Centrosomal protein of 104 kDa, Cep104.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase non-ciliated cells, localizes to the distal ends of both the mother and daughter centrioles. In ciliated cells, present at the distal end of the daughter centriole, but not on the mother centriole, and at the tip of primary cilium. Localization at the ciliary tip is also observed in motile cilia. Throughout S phase, associated with both mother and daughter centrioles in each centrosome. During metaphase and telophase, present at both spindle poles.
Protein: CG23_YEAST
Sequence: MHHNSQSLSSGHIRSPEDENVAPIGNLKHRTGSLSHISSAHPRVALSDVTNIVATNSSNNSISKPKVAPIKERLDSAAIIEEERLDANSVAQRKEADHNDLLTDREQEEPVEDDGESEEDEEEDQEPLLLQHYASDTLVWEHAFRTYYRTTLDPNDDDVYDVVMVAELSNEIFEYMRKLEDLYKPNPYYMDKQPELRWSFRSTLIDWIVQVHEKFQLLPETLYLCINIIDRYLCKEVVPVNKFQLVGAASLFIAAKYEEINCPTIKDFVYMSENCYSRNDLLDAERTILNGLEFELGWPGPMSFLRRISKADDYEHDTRTLAKYLLESTIMDHRLVSAQPSWLAAGAYFLSKIILGQNQWSLAHVYYSNYTQEQILPLATIILENCRYASKRHNAIWRKYSSRRYLHSSQIVAKWIALAEHRVERSN
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.  Interacts with the CDC2 protein kinase to form MPF.  G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
What are the official names of this protein?
G2/mitotic-specific cyclin-3.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: RBSK_LEIMA
Sequence: MHRVQNVQSHVGEYAPDILVVGSCFLDYVGYVDHMPQVGETMHSESFHKGFGGKGANQAVAAGRLGAKVAMVSMVGTDGDGSDYIKELERNGVHTAYMLRTGKSSTGLAMILVDTKSSNNEIVICPNATNYFTPELLRAQTSNYEKILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAEVEQIKPFLPYVSLFCPNEVEAALITGMKVTDTESAFRAIKALQQLGVRDVVITLGAAGFALSENGAEPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLLEACKRANECAAISVTRKGTQLSYPHPSELPAGVT
What is the function of this protein?
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium.  The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.  Specifically phosphorylates D-ribose.  Fails to phosphorylate 4, 5 or 6 D-carbon sugars (erythrose, threose, xylulose, arabinose, fructose and glucose).
What are the official names of this protein?
Ribokinase, RK.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYV_CHLAB
Sequence: MEEDAFPKAYDPKGLEEKLYAFWEESTMFTAQAASDKPPYAIIMPPPNVTGILHMGHALVNTLQDVLIRYKRMSGFEVCWVPGTDHAGIATQTVVERHLYSSLGKRRVDFSREEFLEHVWQWKEKSEGVILSQLRQLGCSCDWSRLRFTMEPLANRAVKKAFKILFDKGHIYRGNYLVNWDPVLQTALADDEVEYEEKDGWLYYIRYRVVGSSEHIVVATTRPETLLGDTAIAISPDDERYSHLLGAKVHLPFVDREIPIIADMSVDPLFGTGAVKITPAHDKDDYRTGMHHNLPMINILTPTGEINENGGIFAGLSKEKARESIITALETLGLFVKKEPYKLRVGVSYRSGAVIEPYLSKQWFVSVDSFRDSLREFVASDAIKIFPPEFTKNYLTWVNNLRDWCISRQLWWGHRIPVWYHKSDAHRMLCYDGEGIPEEVAKDPESWEQDPDVLDTWFSSGLWPLTCLGWPDSECGDLEKFYPTAVLVTGHDILFFWVTRMVLLCSAMVGKKPFSDVFLHGLIFGKSYKRYNDLGEWTYITGEEKYAYDMGKALPKGVIAKWEKLSKSKGNVIDPLEMIAKYGADAVRMALCSCANRGEQIDLDYRLFEEYKNFANKIWNGARFIFSHISNLTSQDLARGIDTTLLGLEDYYILDGFNRLLKELHSAYQNYAFDKITTMAYEFFRNNFCSTYIEIIKPTLYGKQRSKEDQLTKQKLLAVLLVNILGVLHPIAPFVTETLFLKLKEVIGEIKEECSDAITAHALAMLRADSYVVAPYPQSIDIVIPEHLHESFALAERLVYTVRNIRGEMQLDSRASLEVFVICPEGVSIETYVPMVCALGGISSIENLTEEPKDRIYSLGVVEGIRLGVFVPVEHIAKEKTRLEKEKTRLENAIESASRLLSSESFRAKANPDLVCAKEEALKNNRIELQSILDKLASFS
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_ECOL6
Sequence: MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAELDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF4A_YARLI
Sequence: MADGLTDIDSSQITTNYDEVVTSFDDLGLKDELLRGIYGYGFENPSSIQQRAILPVIKGNDVLAQAQSGTGKTATFSISALQNIDEKIKKPQALIIAPTRELAHQIQKVVLAFGEYMKIECHACIGGTSVAEDIRVIQEGVHVIVGTPGRIHDMIERRILKTDLIKMFILDEADEMLSREFKDPIYDIFTTLPETTQTVLLSATMPAEVLDITGKFMRDPVRILVKKDELTLEGIKQFYIDVEQESYKFEVLCDLYETINVSQAVIFCNTRRKVDYLTQALTEADFTVSSMHGETEQSQRDVIMKAFRTGSSRILITTDLLARGIDVQQVSLVINFDLPSNRENYIHRIGRGGRFGRKGVAINFVTSEDHGMLKELERFYSTEIVEMPTNIADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase eIF4A, Eukaryotic initiation factor 4A, eIF-4A, Translation initiation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_CLAM3
Sequence: MAAPKSAVRKPRRKDKKNIAVGQAHIKSTFNNTIVSITDPTGAVISWASSGVVGYNGSRKSTPFAAQLAAESAARQAQEHGMKKVDVFVKGPGSGRETAIRSLQAAGLEVGSINDVTPQAHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: FKBP4_ASPFU
Sequence: MSGLLPVAVYALKVPAGGLLIPAVPDAAATFRVSMAAIDPDETPEFEDGQTRPRATLKLIRPPADMDIDESDDDYEEDSEEDSDDEEINGGPSDKEKARKLKEAAALKELEDEDEDDDSEGDDENFDLKAAISKLVKGKAPATDDDEDDESDEGLELDEMVVCTLDPERHCQQPLDITVAEGERVFFKVTGTHTVYLTGNYVIPAEEGPSEYDEDEDDEDDEDDYDLSPDEDELVDMGDLLDDEEEDELDGLAHPRVTEIESDEEEAPKLVESKGKNKRTADSDEEMALDDMMAKDGKAKGADNGEPAPSKKQQKKLKKNNGEAAAVEQKKEAKVAKEGKEGKEGKEAKEAKKVQFAKNLEQGPTPSGQKPGETTTGTLGVKEVKGVKIDDKKLGKGPAAKAGNTVAMRYIGKLEDGKVFDANKKGKPFTFKLGKGEVIKGWDIGIAGMAVGGERRITIPPHLAYGKKALPGIPANSKLIFDVKLLEIK
What is the function of this protein?
PPIase that acts as a histone chaperone.  Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail.  Proline isomerization influences H3 methylation thereby regulating gene expression.
What are the official names of this protein?
FK506-binding protein 4, Histone proline isomerase, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HYES_RAT
Sequence: MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITFSQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTCIVTNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFPEAPLPVPCSPNDVSHGYVTVKPGIRLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNTPLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTVNKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWSCKALGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILIKWLKTEIQNPSVTSKI
What is the function of this protein?
Bifunctional enzyme (PubMed:8626766, PubMed:12574508).  The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy-octadec-9E-enoic acid (PubMed:12574508).  Has phosphatase activity toward lyso-glycerophospholipids with also some lower activity toward lysolipids of sphingolipid and isoprenoid phosphates (By similarity).
What are the official names of this protein?
Bifunctional epoxide hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome.
Protein: TPIS_SHEPW
Sequence: MALRRPMVAGNWKMNGSAQLAQELFKKFATKLQNDSAEVVLCPPSIYLESVRQLLDENKEALNGCLVRMGTQNVSQHDFGAYTGEISGQMLKDSGCRYVIIGHSERRRMYGETSDIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDVVIEKNGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLIGGVSLNATEFLSLCTIAMSA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUSA_PASMU
Sequence: MIQNQPHFYRGRFSVAPMLDWTTRHCRYFHRQFSQHALLYTEMVTTGAIIHAKYDHLEFSPAENPVALQLGGSDPTQLAQCAKIAQQRGYTEINLNVGCPSDRVQNGMFGACLMAKADLVADCVSAMQTEVSIPVTVKTRIGIDDLDSYEFLCEFVQKVHEAGCQEFIIHARKAWLSGLSPKENREIPPLDYERVYQLKRDFPHLLMSINGGIKTLEEMQQHLQYMDGVMVGREAYQNPSLLGYIDQALFDPTCPVVTPREAVEKMFPYIEQQLSQGVYLNHVVRHMLGAFQSCKGARQWRRYLSENAHKAGAGLEVVEKALSFVAS
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U20 and U20a in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(20/20a) synthase, U20-specific dihydrouridine synthase, U20-specific Dus, tRNA-dihydrouridine synthase A.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusA subfamily.
Protein: SYGB_ALISL
Sequence: MAKNFLIELGTEELPPKALRSLAEAFAANFEAGLKAAGLAHQGIKWYATPRRLALKIAELDEGQADKIVEKRGPAIASAFDADGNPTKAAQGWARGNGITVEQAERLKTDKGEWLLHKEEVKGQPVKGLVVELAAKALAGLPIPKAMRWGNSDIQFIRPVKTLTILLGDELIEGTILGVASTRTIRGHRFMGESEFTIDSADQYPAILEERGKVMADYDARKAIILAGAKKAAEAVGGIADLEDELVEEVTSLVEWPVVLTAKFEQEFLNVPSEALVYTMKGDQKYFPVYDQEKNLLPNFIFVTNIESKEPRHIIEGNEKVVRPRLADAEFFFNTDRKRPLIDRLPELEQAIFQKQLGTIKDKTDRITELAGYIAEQIGADVEKSQRAGLLAKCDLMTSMVFEFTDTQGVMGMHYATHDGEDAQVALALYEQYMPRFAGDDLPSTDVSASVAMADKLDTLVGIFGIGQAPKGSDPFALRRAALGILRIIVEKGYNLDLVDLVAKAQSLFGDKLTNANVDTDVIDFMLGRFRAWYQDEGFSVDIIQAVLARRPTKPADFDQRVKAVSHFRELDAAESLAAANKRVGNILAKFDGELAQEIDLALLQEDAEKVLAEKVEILAEALEPVFIAGNYQEALSRLAELREPVDAFFDGVMVMADDEALKLNRLTLLNKLRNLFLDIADISLLQK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_NOSS1
Sequence: MVTTAEKTNIGYITQIIGPVVDVKFPNGKLPQIYNALTIKGTNEAGQQLNLTVEVQQLLGDNQIRAVAMSSTDGLVRGLEVVDTGAPISVPVGKATLGRIFNVLGEPVDNRGPVNNQETLPIHRPAPKLTELETKPSVFETGIKVVDLLTPYRRGGKIGLFGGAGVGKTVIMMELINNIATQHGGVSVFAGVGERTREGNDLYNEMIESGVINNENLNESKIALVYGQMNEPPGARMRVGLSGLTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGQLQERITSTTEGSITSIQAVYVPADDLTDPAPATTFAHLDGTTVLSRGLASKGIYPAVDPLGSTSTMLQPNIVGDEHYNTARAVQSTLQRYKELQDIIAILGLDELSEEDRLIVARARKVERFLSQPFFVAEVFTGSPGKYVKLEDTIKGFQKILSGELDDLPEQAFYLVGDINEAIAKAEKIKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: PSRP_ECO45
Sequence: MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: AMPP1_AJECN
Sequence: MGPIDTSQRLARLRELMQERKVDVYIVPSEDSHQSEYIAHCDGRREFISGFTGSAGCAIVSMTKAALSTDGRYFNQAAKQLDSNWILLKRGFENMPTWQEWTAEQAEGGKVVGVDPSLITAFDARNLSETIKKCGGSLLGVQENLVDLVWGTERPARPSEKVALHPIEFAGKSFEEKISDLRKELQKKKCAGFVISMLDEIAWLFNLRGNDIPYNPVFFAYAIITQSTADLYIDEEKLPAEVKNYLGDKVSLKPYGSIFEDAKVLGQSAQNKSDGEASTKPPQKFLISTRASWSLSLALGGEKNVEEVRSPITDAKAIKNEAELEGMRACHIRDGAALSEYFAWLENELVNKKTVLNEVDASDKLEQIRSKHQHFVGLSFDTISSTGPNAAVIHYKAERNNCSIIDPKAVYLCDSGAQYLDGTTDTTRTLHFGEPTEMEKKAYTLVLKGLISIDTAVFPKGTTGFALDAFARQYLWKEGLDYLHGTGHGVGSYLNVHEGPIGLGTRVQYSEVAIAPGNVISDEPGYYEDGVFGIRIENIIMAKEVKTTHKFGEKPWLGFEHVTMTPLCQKLINPSLLSDAEKKWVNDYHTEIWEKTSKYFENDELTRNWLKRETQPI
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: S46A3_RAT
Sequence: MKISFIEPAILLYAFAMTLTIPLTAQYVYRRIWEETGNYTFTSSSNVSECEQNKSSSTFAFQEEVQKKASLFSLQVEISGLIPGLVSTFMLLSSSDNHGRKLPMVLSSLGSLGTNLWLCAMSYFDLPLQLLVASTFIGALFGNYTTFWGACFAYIVDQEKEYKHRIIRIAVLDFMLGVVTGLTGLSSGYFIRELGFAWSYFIIAVVVLVNLAYILFFLSDPIKESSSQIVTMSCSESLKDLFYRTYMLFKNGSCKRRSLLCLLIFTLVVYFFVVFGITPVFTLYELGPPLCWNEVYIGYGSALGSLSFLSSFLGIWLFSYCLKDIHIAYVGIFTTMVGMMLTAFTRTTLMMFLVRISFFFTIMPLSILRSMLSKVVHSTEQGVLFACIAFLETLGGVTSTSAYNGIYSATVAWYPGFVFLLSAGLLVLPAVSLCMVKCIGWEEGSYTLLIHDEPSEHTSDS
What are the official names of this protein?
Solute carrier family 46 member 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SLC46A family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PUP_CORJK
Sequence: MAQGGQVSAGGGRRDDDEPIEQTSGAGTQQVNVTGTDDLLDEIDGLLENNAEEFVRSYVQKGGQ
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: RL4_PECAS
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARAGSVKSPIWRSGGVTFAAKPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEQFSLEAPKTKLLVEKLKEMALEDVLIITGELDENLFLAARNLYKVDVRDAAAIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PTP4_STYPL
Sequence: SKSASIVMLTELVERGQAKCAQYWPNDGILTFGDIEVEFLSVNESEDYSERDFKVSNRSDNNGSQLIVKQFHYHGWPEVGAPVSGYSMIELVEDVQKQQQNSGNHPIVI
What are the official names of this protein?
Tyrosine-protein phosphatase 4.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: BRAF_HUMAN
Sequence: MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH
What is the function of this protein?
Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable).  Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126).  May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179).
What are the official names of this protein?
Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Protein: ATPB_STRPM
Sequence: MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIVLEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDLEEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQMGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDEEKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDDLPEDAFRSVGPIEDVIKKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TET3_XENTR
Sequence: MDTQPAPVPHVLPQDVYEFPDDQESLGRLRVSEMPAELNGGGGGGSAAAFAMELPEQSNKKRKRCGVCVPCLRKEPCGACYNCVNRSTSHQICKMRKCEQLKKKRVVPMKGVENCSESILVDGPKTDQMEAGPVNHVQEGRLKQECDSTLPSKGCEDLANQLLMEANSWLSNTAAPQDPCNKLNWDKPTIPNHAANNNSNLEDAKNLVAFSAVAEAMSTYGMPASGTPSSVSLQLYEKFNYETNRDNSGHLEGNAPSCPEDLNTLKAALALAKHGVKPPNCNCDGPECPDYLEWLENKIKSTVKGSQESPFPNLGQVSKELVQKQYPKEQVLNLENKNSTCPSGNLPFSQNALSLAKEKNISLQTAIAIEALTQLSSALPQTNNECPNAPSQPLINPHDQLTHFPSAKGNQLPMLPVARNELFQNQQSQLYTGKNALPVPQSPRQTSWEQNKKSSYQEGQYIPENLSHSSSVLPSDASTPQKPEFLQQWVQNADLLKSPSDPMTGLKQLLGNTDEYIKSVFKGPEALPNKKNVKPKHTIKSIKKESTEFLKMSPDQQLSQLLQTNEFHRNTQAALQQHLHHKRNLFVDPNAMEACTQEQQNWWVPSSQQAPVSKTTEKPVKERKKRRQSPSQKQVEPKPKPQRKQVQIKKPKVKEGSAVFMPVSQISLDTFRRVEKEENQGKEMDAENSLPNNVQTELLESQSLQLTGSQANPDDRKTVNTQEMCNENQSNIGKANNFALCVNRANSFVAKDQCPTPSTHDTSSSSGQGDSANQHTNVSDVPGQNDLSCLDDKLEDLIRQFEAEFGEDFSLPGSAVPSQNGEGPPKQTPSGDPQFKLPFPSQLLPPENSTKPATHSNPALSNNPVSREVSNNLDSLFSSKSPKQIKIESSGAITVVSTTCFYSEENQHLDGTPTKSDLPFNPTLSGFLDSPLKYLTSPTKSLIDTPAKKAQAEFPTCDCVEQINEKDEGPYYTHLGSGPTVASIRELMEERFGQKGDAIRIEKVIYTGKEGKSSRGCPIAKWVIRRQSEDEKLMCLVRQRAGHHCENAVIIILIMAWEGIPRSLGDSLYNDITETITKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFRLIGENPKEEDGLKDNFQNLATKVAPVYKMLAPQAYQNQVNNEDIAIDCRLGLKEGRPFSGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRMIGRVAEDEQLHVLPLYKVSTTDEFGSEEGQLEKIKKGGIHVLSSFPREVRKLSEPAKSCRQRQLEAKKAAAEKKKLQKEKLVSPDKTKQEPSDKKTCQQNPGVPQQQTKPCIKVEPSNHYNNFKYNGNGVVESYSVLGSCRPSDPYSMNSVYSYHSFYAQPNLPSVNGFHSKYALPPFGFYGFPNNPVVPNQFMNYGTSDARNSGWMNNCFEKKPELQSLADGMNQSYGSELSEQSFRRSSEVPHHYSLQNPSSQKSVNVPHRTTPAPVETTPYSNLPCYNKVIKKEPGSDPLVDSFQRANSVHSHSPGVNHSLQASDLPISYKANGALSSSGRTNAESPCSMFMPNDKNGLEKKDYFGVHSNAPGLKDKQWPPYGTDVSVRQHDSLDSQSPGKVWSSCKLSDSSAALPSSASTQDKNWNGRQVSLNQGMKESALFQEKLWNSVAASDRCSATPSDRSSITPCSELQDKNWGSFPNPTVNSLKTDSSQNHWDPYSLDDNMDDGQSKSVKEEDDEEIWSDSEHNFLDENIGGVAVAPGHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARAREEEAAKLGIKQEVKSLGKKRKWGGAATTETPPVEKKDYTPTRQAATILTDSATTSFSYAYTKVTGPYSRFI
What is the function of this protein?
Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.  Conversion of 5mC into 5hmC probably constitutes the first step in cytosine demethylation.  Selectively binds to the promoter region of target genes and contributes to regulate the expression of numerous developmental genes, including pax6, rax, sox9 and six3.  May also contribute to the regulation of target genes in ways that do not require its enzyme activity.
What are the official names of this protein?
Methylcytosine dioxygenase tet3.
What is the protein family that this protein belongs to?
Belongs to the TET family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Detected on chromatin, where it binds to target gene promoters.