PharMolix/UniProtQA huggingface dataset:
Protein: THIC_ECO8A
Sequence: MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: UREG_BURVG
Sequence: MNAPASSPARRTKKLPPLRVGIGGPVGSGKTTLLEMLCKAMRDTYDLVAITNDIYTKEDQRLLTVAGALPEERIMGVETGGCPHTAIREDASINLEAVDRMLSRFPDADIVFIESGGDNLAATFSPELSDLTIYVIDVAGGEKIPRKGGPGITKSDLLVINKTDLAPLVGANLDVMASDTKKMRGERPYVMTNLKALDGVADVIAFIEKKGLLTV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_CALS8
Sequence: MIDVQSQKDLRGIAIQKVGIKDLNWPIVVMDRANKTQTTIAKITAAAELKGDMRGTHMSRFIEAIDELNVVGPKEIERLLDRIKEKLDSQKAYVRFDFPYFINKRTPVTETLAPLKVDCYFEAEKGEKFDLKVGVIVPVHTLCPCSKEISEYGAHNQRAYVTIEVKMRRFMWIEELVEIAESSASCPLYSILKRPDEKWVTERAYQNPRFVEDLLREVVVKISGDKRIKWYKVFVESIESIHNHNAFAYIEGENTK
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: SCRK3_ARATH
Sequence: MASSTGEKGLIVSFGEMLIDFVPTVSGVSLSESPGFLKAPGGAPANVAIAVSRLGGRAAFVGKLGDDDFGHMLAGILRKNGVDDQGINFDEGARTALAFVTLRSDGEREFMFYRNPSADMLLRPDELNLELIRSAKVFHYGSISLITEPCRSAHMKAMEVAKEAGALLSYDPNLREPLWPSPEEARTQIMSIWDKADIIKVSDVELEFLTENKTMDDKTAMSLWHPNLKLLLVTLGEKGCTYFTKKFHGSVETFHVDAVDTTGAGDSFVGALLQQIVDDQSVLEDEARLRKVLRFANACGAITTTKKGAIPALPTDIEALSFLKDQKKRQTNLKFSKWCCTASPC
What is the function of this protein?
May play an important role in maintaining the flux of carbon towards starch formation.
What are the official names of this protein?
Probable fructokinase-3.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: RL15_CALS8
Sequence: MKLFELKPAPGAKKRPKRVGRGESSGHGKTSTRGHKGQWARSGGGVRPGFEGGQMPLTRRIPKRGFKNINKKVYTEVNVEKLERFENDTVITPELLLKEGVISKIEKDGVKVLGRGDLTKRLIVRVQKVSEGARKKIEAVGGKVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: DXS_BRUO2
Sequence: MSRPSTPLLDKVPTPDRLRALPERDLPQLAEELRTELIDAVSTTGGHLGAGLGVVELTVALHHVFNTPYDRIIWDVGHQAYPHKILTGRRDRIRTLRQAGGLSGFTKRAESEYDPFGAAHSSTSISAGLGMAVASELSGEKRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDMSIAPPTGAMSAYLARLVSGRTYRSVREAAKQVAQKLPKFLQDKARKSEEYARAFFTGGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDTQKGPVLIHVVTQKGKGYAPAEAAADKYHGVNKFDVITGKQAKPPANAPSYTKIFGTSLIEEARHDDKIVAVTAAMPTGTGLDLFGEAFPKRVFDVGIAEQHAVTFAAGLASEGYKPFCAIYSTFLQRGYDQVVHDVSIQNLPVRFPIDRAGLVGADGPTHAGSFDTGFLAALPGFVVMAASDEAELRHMVRTAAEYDEGPISFRYPRGDGVGVDLPERGSVLEIGKGRIVREGTKVALLSFGTRLQECLAAAEELGAAGLSTTVVDARFAKPLDHDLIRRLAREHEVLVMVEEGAVGGFGSHVLQFLATDGLLDRGLKVRALTLPDIYQDHGKPDAMYAEAGLDRTGIVRTVFAALHRDELGHEALPTPFRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: MURC_RHOPA
Sequence: MRLPRHIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASESANVNRLREKGIQIHVGHQADNIKGADVLVVSTAIKRDNPELLAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSMVAALLDAGDLDPTVINGGIINAYGTNARLGGGDWMVVEADESDGTFLKLPADVAIVTNVDPEHLDHFKTFDAVQDAFRNFVENVPFYGFAVMCIDHPVVQTLVGKIEDRRIITYGENPQADARLLDLAASGGGSTFKVAFRDRKAGTAHEIADLKLPMPGRHNALNATAAIAVAHELGLSDDTIRKALAAFGGVRRRFTKTGEWNGVTIIDDYGHHPVEIAAVLKAARQSTAGKVIAVVQPHRFSRLQSLFEEFCTCFNDADAVIVADVYPAGEAPIEGIDRDHFVLGLRAHGHRDVVALQDSASLAGVVAGLAHSGDYVVCLGAGNITQWAYALPGELKALG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_XANP2
Sequence: MNHLKTAILLAGLTALFMAVGFAIGGRGGMMIAFVVASATNLFSYWNSDKMVLRMYGAREVDETTAPDFVRMVHELARRADLPPPRVFIMDNPQPNAFATGRNPQNAAVAATTGLLQSLSPEEVAGVMAHELAHIKHYDTLTMTMTATIAGAISMLANFGLLFGGGNRNNNNPFGAIGTILMVILAPLAAMLVQMAISRSREYEADRGGAEILGRPMALASALAKISGAAHEVPNYEAESNPATAHMFIINPLSGARMDNLFSTHPAVENRIAALRALSQQMGGGGFAPGPAPAVRPPGGNPWGVDPGGGQRRGPWG
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTXL_SCHPO
Sequence: MLQLFIYSPGLGQPTMDPGCLAALIYCALAVPKDEIEILRTANSGMSPTHKLPALWDGHVWIGSLKNILIYLKQKGYNLDNFDAKQLANVMAFTSLLEGSVNDLWLLEAFVNEENFVEAIRPAWSKALKFPHNYLTPNALQRQAKERLAQTLGIRDEEVSYEASRMPISHKWTNATRHRQALLRTQARRIRISSLARQVYGSLESLISDSKFIFGEKPTSLDCLFYAYLSFHAFTNELPQATLRPCLQFNSPKLYAYLKSLRETWFSDDSNILSPLSIKVQPENLLTIARLAWNNVTAKANDTRKSITKFSVPPERKLLWARNGFFIFASAFSFVWFVISNGIVVIETEDDEASFEEVDDAKESIQEKEIDETTESKATHDSSETSSSKELPKEEEKESSSFDLQPLSAQDLLFSGFAEDEIMDEEFGYDDDDDEEFDLDDLDDLEEEIV
What is the function of this protein?
May be involved in transport of proteins into the mitochondrion.
What are the official names of this protein?
Metaxin-like protein C409.19c.
What is the protein family that this protein belongs to?
Belongs to the metaxin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion outer membrane.
Protein: RL20_TERTT
Sequence: MARVKRGVVARRSHKKVLKAAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRNKKRNFRALWITRINAQSRAEGMSYSRLIAGLKKAEITLDRRVLADLAIHDKPAFAAIVAKAKDALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: UNC5B_RAT
Sequence: MRARSGARGALLLALLLCWDPTPSLAGIDSGGQALPDSFPSAPAEQLPHFLLEPEDAYIVKNKPVELHCRAFPATQIYFKCNGEWVSQKGHVTQESLDEATGLRIREVQIEVSRQQVEELFGLEDYWCQCVAWSSSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQACQKTACTTVCPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCVLNQRTLNDPKSRPLEPSGDVALYAGLVVAVFVVLAVLMAVGVIVYRRNCRDFDTDITDSSAALTGGFHPVNFKTARPSNPQLLHPSAPPDLTASAGIYRGPVYALQDSADKIPMTNSPLLDPLPSLKIKVYDSSTIGSGAGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLTIPGTGVSLLVPNGAIPQGKFYDLYLRINKTESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIAGDWIFQLKTQAHQGHWEEVVTLDEETLNTPCYCQLEAKSCHILLDQLGTYVFTGESYSRSAVKRLQLAIFAPALCTSLEYSLRVYCLEDTPAALKEVLELERTLGGYLVEEPKTLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQKALHCTFTLERHSLASTEFTCKVCVRQVEGEGQIFQLHTTLAETPAGSLDALCSAPGNAATTQLGPYAFKIPLSIRQKICNSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMTTDGDC
What is the function of this protein?
Receptor for netrin required for axon guidance.  Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.  Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion (PubMed:10399920, PubMed:9126742).  Functions as netrin receptor that negatively regulates vascular branching during angiogenesis.  Mediates retraction of tip cell filopodia on endothelial growth cones in response to netrin (By similarity).  It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:11387206).  Mediates apoptosis by activating DAPK1 (PubMed:18582460).  In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity (PubMed:15729359).
What are the official names of this protein?
Netrin receptor UNC5B, Protein unc-5 homolog 2, Protein unc-5 homolog B.
What is the protein family that this protein belongs to?
Belongs to the unc-5 family.
Protein: RBSD_ECO8A
Sequence: MKKGTVLNSDISSMISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAAIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG12_MOUSE
Sequence: MSEDSEVVLQLPSAPVGAGGESLPELSPETATPEPPSSAAVSPGTEEPPGDTKKKIDILLKAVGDTPIMKTKKWAVERTRTIQGLIDFIKKFLKLVASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG
What is the function of this protein?
(Microbial infection) May act as a proviral factor.  In association with ATG5, negatively regulates the innate antiviral immune response by impairing the type I IFN production pathway upon vesicular stomatitis virus (VSV) infection.
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=TECPR1 recruits the ATG12- ATG5 conjugate to the autolysosomal membrane.
Protein: SELO_RHOPA
Sequence: MTAHFPFDNSYVALPPNFFARVAPTPVAAPRLIKLNRPLAVQLGLDPDLLETPEGAEILSGNQMPETAASIAMAYAGHQFGNFVPQLGDGRAILLGEVVDRNGVRRDIQLKGAGRTPFSRMGDGRAALGPVLREYIVSEAMAALGIPTTRSLAAVLTGETVLRDPIQPGAVLTRVASSHIRVGTFQYFAARGDLASVRALADHAIARHYPEAAQAPSPYLALLEGVIGRQAELVASWMMVGFIHGVMNTDNCSVAGETIDYGPCAFMDTFDPKTVYSSIDQFGRYAYGNQPPIALWNLTRLAECLVRLLADDDDKGIEIAQTALGGFAEQFNAAYLAKLAAKLGLFTSQPDDQQLSQEFLTALAKGEADFTLAFRRLSDAAVDPSDLGEVRALFADPAAFDEWAPRWRARIATEPQDATTRQAAMRRVNPAYIPRNHRIEAVIRAAVDRDDFAPFEEILTVLANPFEEKAEFARYAEPPQPHEQVLETFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: PTA_DEIGD
Sequence: MKTLFIAPTRNGVGLTSTALGLLRALERQGLKVAFLKPIAQTHEAAPDDSVHWARTLAHAVTPDPILLSVAEEQLSQGQEEELMENVVALAREAAAGVTGGADVLVVEGLALNERNVYAGPLNASLARNLEADVVLVSSLAGVTPATLADELEIAAQAYRRSDGSGLAGYVLNFAPLELDFGGLLADLRARSRILASGELPLLGVIAQSPTLAAPRTLDVARHLGAEVLNEGEARLRRVTSTVVTARSVPKMADLFTSGALVVTPGDREDVVMAAALSHLSGVPLAGLLFTSGSTPEAAIERLCRAALTSTLPVLRVETNSYNTASRLSRMEARVPHDDLERMERTLDFIADRLDTVPLGTRLRAPEGSERRLPPSAFRYELIQKARAANKRIVLPEGDEPRTVRAAIRCVEKGIARCVLLAQPEKVRQVAEGQGLTLPDGLEIIDPDRVRANYVAPMVELRKHKGLTAPQAEAQLEDNVVLGTMMLALDEVDGLVSGAVHTTANTVRPALQLIKTAPGVRLVSSIFFMLMPEQVVVYGDAAINPNPNAEELADIAIQSADSARAFGIPPRIAMLSYSTGESGAGADVEKVRIATRLVRERRPDLPVDGPLQYDAASVLSVGRQKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRAAGVVAVGPMLQGLRKPVNDLSRGALVDDIVYTIALTAIQATQAREGA
What is the function of this protein?
Involved in acetate metabolism.
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_BORHD
Sequence: MIKKYEACFLFKSEELEYKVALEDVKKQLTAFNASDFVENSLGERALEYSIRKQSRGRYEIIEFKMDSSNLKELEVQLRLIKNLLRYMILVKINKKVNVKKVKRRNFREFKDNRDTREKELPESTADVKVD
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TRPF_STAEQ
Sequence: MIVKFCGFKTESDIKKIKKLEVDAVGFIHYPDSKRHVSLKQLKYLAKIVPDHIEKVVVVVNPQMSTIKRIINQTDINTIQLHGNESIQLIRNIKKLNSKIRIIKAIPATRNLNNNIQKYKDEIDMFIIDTPSITYGGTGQSFDWKLLKKIKGVDFLIAGGLDFEKIKRLEIYSFGQCGYDISTGIESHNEKDFNKMTRILKFLKGDE
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: GPA1_USTMA
Sequence: MGCGASKVDKEGQARNDAIDAQLKKDRLAQKNEIKMLLLGAGESGKSTILKQMKLINHGSYSAEERESYKEIIFSNTVQSMRVLLDAMERLDIPLADATNAPRAEIILGLSPSIESSVLPRQVADAIHALWGDAGVQACFGRSREYQLNDSAKYYFDSIQRMAEPSYLPTDQDVLRSRVKTTGITETHFKIGELNYKLFDVGGQRSERKKWIHCFENVTAIIFLVAISEYDQLLYEDENVNRMQEALTLFDSICNSRWFVKTSIILFLNKIDLFKQKLPISPMADYFSDYTGGADYNSASEYIVNRFVSLNQSDAKTIYTHFTCATDTSQIKFVMSAVNDIIIQVNLRDCGLL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-1 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: RL31_KLEP3
Sequence: MKKGIHPKYEEITATCSCGNVMKIRSTVGHDLNLDVCGKCHPFFTGKQRDVATGGRVDRFNKRFSIPGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: LOADS_BPT4
Sequence: MSLFKDDIQLNEHQVAWYSKDWTAVQSAADSFKEKAENEFFEIIGAINNKTKCSIAQKDYSKFMVENALSQFPECMPAVYAMNLIGSGLSDEAHFNYLMAAVPRGKRYGKWAKLVEDSTEVLIIKLLAKRYQVNTNDAINYKSILTKNGKLPLVLKELKGLVTDDFLKEVTKNVKEQKQLKKLALEW
What is the function of this protein?
Forms the sliding-clamp-loader together with the small subunit (PubMed:10585481).  The clamp loader holds the clamp in an open conformation and places it onto the DNA (PubMed:22194570).
What are the official names of this protein?
Sliding-clamp-loader small subunit, Clamp loader gp62 subunit, Gene product 62, gp62.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae sliding-clamp-loader small subunit family.
Protein: PHDT_NOCSK
Sequence: MNTSPGAPTGVRAFVDSQPIGRRQRIIVLMVFLIMVADGMDITLASHLFPPVIRDWGVPVSAVTLVVSLGVVAMAIGALVSGPVADRWGRKGVTVVGFVLFCLATAGLGLTGDIHSFAALRIISCFGLGAVMPVALTIVADWMPKARRAQMVSIAFAGVGVGSIIGAYLAAAVIPTLGWQVMVLIAGLAPLIILPFFVALVPEPAIISVRRGIPEARIRSALALVAPDRDIAGVDLTRAGLTLGAGEVRAKALFAEILCRPLLGVTLLIWGVFFVVQGSGLLVLQYMPMLLQAPAPGLSTVESGLIVAMYGWGALIGQLTIAFILKRFDRFIALAAFIFWSVVGLLIVAAFGTGFGFFGYFTLLFAIGLSLPATAAAMQSVTTLAYEEEFRATGMGSAGFAGRLGTLTYGALGGTLIGAGFGITTVSLVLAAPLAVSIGLVFSLRALSRRAGIAPEPHQITPGNEVDDAHVST
What is the function of this protein?
Probably involved in the transport of 1-hydroxy-2-naphthoate.
What are the official names of this protein?
Probable 1-hydroxy-2-naphthoate transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIK_ECOSM
Sequence: MPFRSNNPLTRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGEVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRRLKRLHKAREPRPLRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTDQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.
Protein: Y364_STRU0
Sequence: MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGDPDPESNSALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSNVNRTAANVRTAYGKNGGNMGASGSVSYMFDKKGVIVFEGDDADTVFEQLLEADVEVDDVEAEDGAITVYTAPTDLHKGIQALRDNGIETFKVTELEMIPQSEVTLEGDDLATFEKLVDALEADDDVQKVYHNVADF
What are the official names of this protein?
Probable transcriptional regulatory protein SUB0364.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_ACIBC
Sequence: MNHPSELKYARTHEWVKIEGDLVITGITDHAQDELGDLVYVETPEVGSQVTAGEQAGVVESVKTASDIHAPVSGTVVEVNTDLEDDPDFVNEDPYGKGWIYKIKPDNIADVEKLLTNAEYEAGL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: MURE_PHOLL
Sequence: MADRNLRDLLAPLGIDAPVRELREMTLDSRKSSAGDLFVAIKGHQTDGRHYIPQAIAQGVAAVIAEAQGEVDNGTVQIMHGVPVVYVNDLNNKLSQLAGEFYCHPGDKLHLIGVTGTNGKTTTTQLLAQWSHGLGETSAVMGTVGNGLLGRVAPSENTTGSAVDIQLDLQQLVRQEATFAAMEVSSHGLVQGRVAALPFEAAVFTNLSRDHLDYHGDMEHYEAAKWLLFSTHNVKQQIINADDEIGLKWLSRLPQAVAVTMENRLPENWQGRWLAAREIKYHDKGVSITFESSWGGGTIDSSLMGAFNVSNLLLALSTLLALDYPLEKLLETASCLEPVCGRMEVFTTPGKPVVVVDYAHTPDALEKALMAARLHCQGKLWCVFGCGGDRDKGKRPLMGGVAEQLADYVIVTDDNPRNEEPQAIIADILTGFLDPGRAIAIHGRVEAVTNAIMQAKADDVVLIAGKGHEDYQLVGHRRLDYSDRLTVARLLGVIA
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_XANCB
Sequence: MTTEAKCPFNHSVVGAGTTNRDWWPKQLRVDLLNQHSARSNPLAASFNYAEAFKRLDLQTLKQELRALMTDSQDWWPADFGHYGPLFVRMAWHSAGTYRTGDGRGGGGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQAISWADLMILTGNVALESMGFKTFGFAGGREDTWEPDQDLYWGRETKWLGGDDRYAHGSPGVDQAHGVLVKDDDSEVQHTRDLENPLAAVQMGLIYVNPEGPDGNPDPLLAAKDIRDTFGRMAMNDEETVALIAGGHTFGKTHGAADAAHVAAEPEASDLESQGLGWHNSFGSGKGGDTITSGLEVTWTTTPAQWSNDFFDHLFGFEWELSKSPAGAHQWVAKNAQAIIPDAHDASKKRLPTMLTTDLALRIDPAYEAISRRFHANPDQFADAFARAWFKLTHRDMGPRARYLGADVPAEELLWQDPIPALNHALIDAQDAAALKQTVLSSGLSVAQLVATAWASASSFRGSDKRGGANGARIRLAPQKDWASNEPAQLAQVLATLERIQADFNARQSGGKQISLADLIVLGGNAAVEQAAHAAGHAVTVPFAPGRMDASQAQTDVESFAVLEPVADGFRNYAKARYAVSAEALLIDKAQLLTLTAPEMTVLVGGLRVLGANTGQSHNGVFTTRPGVLSNDFFANLLDMRTEWKATSETKETYEGRDRATGEHKWTGTRVDLVFGSNSILRAVAEVYASADAQEKFVQDFVAAWTKVMQLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: FUS_MEASE
Sequence: MGLKVNVSAIFMAVLLTLQTPTGQIHWGNLSKIGVVGIGSASYKVMTRSSHQSLVIKLMPNITLLNNCTRVEIAEYRRLLRTVLEPIRDALNAMTQNIRPVQSVASSRRHKRFAGVVLAGAALGVATAAQITAGIALHQSMLNSQAIDNLRASLETTNQAIEAIRQAGQEMILAVQGVQDYINNELIPSMNQLSCDLIGQKLGLKLLRYYTEILSLFGPSLRDPISAEISIQALSYALGGDINKVLEKLGYSGGDLLGILESRGIKARITHVDTESYFIVLSIAYPTLSEIKGVIVHRLEGVSYNIGSQEWYTTVPKYVATQGYLISNFDESSCTFMPEGTVCSQNALYPMSPLLQECLRGSTKSCARTLVSGSFGNRFILSQGNLIANCASILCKCYTTGTIINQDPDKILTYIAADHCPVVEVNGVTIQVGSRRYPDAVYLHRIDLGPPISLERLDVGTNLGNAIAKLEDAKELLESSDQILRSMKGLSSTSIVYILIAVCLGGLIGIPALICCCRGRCNKKGEQVGMSRPGLKPDLTGTSKSYVRSL
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with H at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: UBC4_MIMIV
Sequence: MEQIVTFGGITIDNVSPDHIQQLYSVKLNGTSNNEEIPTEFPNIIQSVCSCDKHVVELTMDVFKLVDTTENSSCAICRYQENEPCIEHKSSESNTKCPIAQSVSCSHSFHACCISRWLHTKKTCPLCNIEWQLIGANNDSVVIYFDDKNQEFKLSDNLVEDIGRQFGIDMDNYIVCKNKSPVTEYKNSTYALCTRDRHNSQNGQTNLKIICEFDSKTENLFIKYSTTIEELRKLVSQTFDLFKDQVKLIYNNIEISKDFDNLTVFNIGIKNDSNLAVECYKSFTYDMEITNNFMVLYVPDTFNTTNSSNNIQSVVSGSIAWIPQPFIDNVTNKDLRCLLSSLYILVKKVNLNTELIQSVTDRFEKYMELYGMHYRQIKLAKDSLRCLLEMNHFNNKDRMILSCTFYELIDRIQRDNNINKNPLLSSNLICNLILSDKQVNEQTKINWKFLAKDVRITKVFNIYSPLVLTNSVPPLLTLNKNLDVVVFTGKGKDVSLPIILYDTLTNSETDVNAAELGKIVSDKGDLMMVDDRIYEEAIMVCIDTSNSMSKASDFDEDIKLKRSSIIETKNRFYEILKTESHSSPQESDIRQLTNTIIWFITHPNFEDWYRKLYSQELIRSIACFEQKVYPNFAMMLVKYPWFFNKLLTSKKVVVNNTWYSFIRNESNSNYNETKYSKEPLQEFLCPISHEIMEHPVVAKDGFTYEKSNILKWFENKSTSPMTNEKISKKICDNKVLKSIIRDWKENNTVIEQSDKLSVTIKLPDPWNETVIHYNETDNIWDLIYQIYHITGLSHDQYKLTSNYWAIDKSSLIKQISSKIKIHPFEKKMVDVKICDKTYFFGTENTMTVSSFYTVGNLLYKLKSRKYHRYAVWYGLKDSGDGFQRGTILSPHDKLIDYSEMTLEIHSSNRYKTPKGNHLSRLDVVKKLFDAYINRSIAYSFNTAIGLMSFSDKSVLECAISPFYESFREKVNELDTSGATALYECLKDSIENLIEWKNADLENRSKAKLRIICLTDGKDTGLDKFKNTVKHKSQYHNVTIDCILIGSDYDNYLGKIGEKTNGYVFNPSTIKYALDIMELETMISSTNRKTIFYHNTIDEKTIPPIINPTKKLHAKAISPMEIISKTNENTKLSQKLIRVQREIVDVMKNQHPDIDVYINEQDISFWKIVFKGPDSTPYKNGTWLAYIQFTEEYPNIAPNIRFVTPIKHCNINNYGRVCHSILDRNYTPNVKISLILQCIYGLLLNPDVNDPLDTNLAMIYYDANGLYEAQIIDYVNKFALKSREEWNQELAKNQFKNW
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Also acts as an E3 ubiquitin-protein ligase.
What are the official names of this protein?
Probable bifunctional E2/E3 enzyme R795.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ubiquitin-conjugating enzyme family.