PharMolix/UniProtQA huggingface dataset:
Protein: VAPC2_HAEIN
Sequence: MLKYMLDTNIVIYVIKRRPLEILSRFNQNAGKMCVSSITVAELYYGAEKSEYPERNIAVIEDFLSRLTILDYQPKHAAHFGNIKAELSKQGKLIGENDIHIAAHARSEGLILVSNNLREFERVIALRTENWV
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its cognate antitoxin is VapB2 (By similarity).
What are the official names of this protein?
Ribonuclease VapC2, RNase VapC2, Toxin VapC2.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: ALGJ_PSEAE
Sequence: MTQSISRPLQYAYIAAFGGLLLGLAGWSLKSVPGFSAAADTPLLNGKLAHAFEAHYDKEFPIKRLGTNLWAALDYTLFHEGRPGVVIGKDGWLFTDEEFKPAPSGQQLEDNWALVRGVQRELNRRGVKLVLAVIPAKARLYPEHIGREQPAALHDSLYQDFLARARAAGIDSPDLLGSLRQAKDNGAVFLRTDTHWSPLGAETVAQRLGAEIRETHLLDVPAQNFVTRVGEERTHKGDLLSFLPLDPLFDELLPRPEQLQQRTTEAAPALPGGQQSGAGDDLFGDSQQPRLALVGTSYSANPRWNFEGALKQALSADLINYAKEGKGPLEPMLELLQDEGFRKDPPQLLVWEFPERYLPMASDLSQFDADWVAQLKASGGRDERLAASRND
What is the function of this protein?
Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues.  Acetylation of alginate is important for the architecture of biofilms and increases resistance to opsonic killing in the host.
What are the official names of this protein?
Probable alginate O-acetylase AlgJ, Alginate biosynthesis protein AlgJ.
What is the protein family that this protein belongs to?
Belongs to the AlgJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Periplasmic side. Periplasm.
Protein: RS21_SALA4
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: MABO1_PAENI
Sequence: MDRLVDRDISASMFTATSHDPLPTHVRTVVVGGGIIGASIAYHLSAAGENDTLLLESNVLGSGTSWHAAGLVTGARGTTTMTKLAKYGLDFYSRLEQMSGLDVSFQRCGSLSVARTAGRVDELLYAKDVADQQGVRTEWLTEDRYKELWPLATYSGVAGALLLPDDGHINPGHATVALAKLAHSLGTQIRENVAVHKVLRQGDLVVGVLTDQGIVHCDRVILACGLWTRDLAATAGVKVPLYAAEHIHVRSAEIDGAVPELPVYRDLDNSYYIRHEAGRLLVGAFEPDGLPRPVEEIPSNGFAEFGPEWEHFAPIRAKAEGVVPALASAGFDRFLNAPESFTPDANFAVGETSELSNLFVAAGFNSQGIIFAPGIGKELAEWVISGTPGFDSSAVDVQRFSGHQNNRNYLKARTKEGLGRLYAMHWPNLQMETGRNVRRTPLHARLAELGACFGEVNGGERANWYGAPGTSPTYDYSYGRPNWFDRVAEEHKAAREGVVLFDLSPFAKFEVAGPDALEVCQMAATADIDVETDKAVYTLFLNDRAGIELDGTITRLGLDRFLVVTPSFTQQKTAAYLKRIARGKAAAVFDCTAALATIGVMGPKSRELLSRISPEDWSDEAQRYTHGRMVEIADGYAYSLRVSFVGELGYELYPSADMAVNVLDALWEAGQDLGLKLAGYHALDSLRSEKGFRHLGHDIGPIDDPYSAGLRFTISMDKPGGFLGKDALLKLDPTAPDHRTVYVALEDPDPVFVHDETVYCNGLPVGRMTSGSYGHTLGRAVGIAALEPDADLSGDFEVQCKGRLYPAKVSRRPFYDPKGERLRG
What is the function of this protein?
Catalyzes the oxidative demethylation of 4-methylaminobutanoate produced from the pyrrolidine ring of nicotine.  To a much lesser extent, can also use sarcosine as substrate, but is not active against dimethylglycine, methylaminopropionitrile, methylaminopropylamine, and alpha-methylaminobutanoate.
What are the official names of this protein?
4-methylaminobutanoate oxidase (formaldehyde-forming), MABO, Demethylating gamma-N-methylaminobutyrate oxidase, Gamma-N-methylaminobutyrate oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: ACKA_GEOMG
Sequence: MVILALNCGSSSVKYQLFDWEKKEVVAKGMVERVIIGDSFIMHEVPGRETYRKEYECPDHKVAIDLIIRTLVDGEHGVLKDINEISAVGHRVVHGGEMFTRSVLIDEKVLDAVKDVQHLAPLHNPPNIAGIEAAQAVLPSVPHVAIFDTAFHQTMPEHAYLYPLPYEWYEKYGVRRYGFHGTSHLFVSKRAAVLLGKKPSDCNIITMHIGNGVSHCAIRGGVSIDTSMGLTPLEGAVMGTRCGDIDPAIPAFMMQKENLSAKEIDSILNKKSGVLGVTGRFTDRRDVIENANNGDHRCKVALEIEAYRLKKYIGTYMAVLGRLDAVVFTAGVGEMGWPIREKTIEGLEGIGIKLDRERNKSAMTRKRETLITTDDSPIKVFVIPTDEELVFTEDVVAILDGTYTDHMNFDYSFARQDFVRS
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_PARMW
Sequence: MPPSPLSSGAFYQRWLGPVLANDEGLDAEQLSCTALTALGQASLRRQWPLVSTVLEGLAGDLQRRDLRLEQVLFGCRFPNPVGLAAGFDKNGVAAGLWDRFGFGFAEVGTVTWHGQPGNPRPRLFRLAQEQAALNRMGFNNDGAQALRRTLERQRLAPPGRRPAVLGINVGKSKVTALEQAPEDYASSLELLAPLADYAVINVSSPNTPGLRDLQDSSQLRRLVERLRRLPACPPLLVKIAPDLEDEAIDGIARLAFEEGLAGVIAVNTSLDRLGLEQRRLLQTGRTLAEEAGGLSGAPLRQRALEVIRRLRASAGPALTLIGVGGIDSAEIAWERITAGASLIQLYTGWIFQGPELVPRILEGLQLQLDRHGLRSIAEAVGSGLPWLPGSEDAEG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y797_METJA
Sequence: MYFELAKRNLKRNLLRSILALLGIIIGVAAISSLGILGGGLKQGIMENLGSISNYIIVFPNYQNGYTSFDKRDIEKLRVLNCKVIPVYATSDFVYIKGKNRKAYANIFGIDKNDIKYLNLKVKVSDTSVAVDTFFSNVNDVNVGNQLEIKNISLRICGIYNSTFLFPDNSLILTAKTYRRFYGENNYNYSRIILYVKNINDIDKIKNETDKILNRKEKKCIIISLNSILEAINGVITKVSYFLMGIGAISLLVAGIGIGNVMLMSVVERTTEIGVMRSIGASKKDIIILFLYEALILGVIGSLIGAFLSLFFGYLIVHYLLKTSLSYYAIFYMIIGIIFGILTSLISALYPAYKASKLDPIKSLRNE
What are the official names of this protein?
Uncharacterized ABC transporter permease MJ0797.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCIZ_SALSV
Sequence: MSDIEAQRIAARIDTVLDILVAGDYHSAINNLEILRAELLDQVKDGISPSQAPGSPWEI
What are the official names of this protein?
UPF0509 protein YciZ.
What is the protein family that this protein belongs to?
Belongs to the UPF0509 family.
Protein: ZN346_MOUSE
Sequence: MECPAPDATDAADPGEAGPYKGSEEPEGREPDGVRFDRERARRLWEAVSGAQPAGREEVEHMIQKNQCLFTSTQCKVCCAMLISESQKLAHYQSKKHANKVKRYLAIHGMETIKGDVKRLDSDQKSSRSKDKNHCCPICNMTFSSPAVAQSHYLGKTHAKSLKLKQQSTKGAALQQNREMLDPDKFCSLCHSTFNDPAMAQQHYMGKRHRKQETKLKLMAHYGRLADPAVSDLPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTLVTLGSQTPVQTQPTPKDSSTVQD
What is the function of this protein?
Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity (By similarity) (PubMed:10488071).  May bind to specific miRNA hairpins (By similarity).
What are the official names of this protein?
Zinc finger protein 346, Just another zinc finger protein.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Note=Nuclear at steady state, primarily in the nucleolus. Shuttles between the nucleus and cytoplasm when associated with XPO5 (By similarity).
Protein: OSMR_MOUSE
Sequence: MAFSVVLHPAFLLAVLSLRASRSEVLEEPLPLTPEIHKVSFQLKLQEVNLEWTVPALTHEELNMIFQIEISRLNISNTIWVENYSTTVKREEAVRWNWTSDIPLECVKHFIRIRALVDDTKSLPQSSWGNWSSWKEVNAKVSVEPDKSLIFPKDKVLEEGSNVTICLMYGQNVYNVSCKLQDEPIHGEQLDSHVSLLKLNNVVFLSDTGTNINCQATKGPKRIFGTVLFVSKVLEEPKNVSCETRDFKTLDCSWEPGVDTTLTWRKQRFQNYTLCESFSKRCEVSNYRNSYTWQITEGSQEMYNFTLTAENQLRKRSVNINFNLTHRVHPKAPQDVTLKIIGATKANMTWKVHSHGNNYTLLCQVKLQYGEVIHEHNVSVHMSANYLFSDLDPDTKYKAFVRCASANHFWKWSDWTQKEFSTPETAPSQALDVWRQVWSENGRRIVTLFWKPLLKSQANGKIISYNIVVENEAKPTESEHYCVWAPALSTNLSLDLQPYKIRITTNNSMGASPESLMVLSNDSGHEEVKEKTIKGIKDAFNISWEPVSGDTMGYVVDWCAHSQDQRCDLQWKNLGPNTTSTTITSDDFKPGVRYNFRIFERSVEHKARLVEKQRGYTQELAPLVNPKVEIPYSTPNSFVLRWPDYDSDFQAGFIKGYLVYVKSKEMQCNQPWERTLLPDNSVLCKYDINGSETKTLTVENLQPESLYEFFVTPYTSAGPGPNETFTKVTTPDARSHMLLQIILPMTLCVLLSIIVCYWKSQWVKEKCYPDIPNPYKSSILSLIKSKKNPHLIMNVKDCIPDVLEVINKAEGSKTQCVGSGKLHIEDVPTKPPIVPTEKDSSGPVPCIFFENFTYDQSAFDSGSHGLIPGPLKDTAHQLGLLAPPNKFQNVLKNDYMKPLVESPTEETSLIYVSQLASPMCGDKDTLATEPPVPVHGSEYKRQMVVPGSLASPSLKEDNSLTSTVLLGQGEQ
What is the function of this protein?
Associates with IL31RA to form the IL31 receptor (PubMed:9920829).  Binds IL31 to activate STAT3 and possibly STAT1 and STAT5 (By similarity).  Capable of transducing OSM-specific signaling events (By similarity).
What are the official names of this protein?
Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31 receptor subunit beta, IL-31R subunit beta, IL-31R-beta, IL-31RB.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 2 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: IF1_BLOPB
Sequence: MTKEDSFEMHGTVLDTLPNTMFRVKLENGHVIVAHISGKIRKNYIRILTGDKVTVELTPYDLSKGRIIFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_BRUA2
Sequence: MRVDLFDFDLPEERIALRPVEPRDHAKLLHVRPGEPFEDRHVYDLPDLLQPGDALVFNDTKVIPAQLEGMRERTGNISQVSATLHMRVGPDRWKAFLRPAKRVKEGDRIRFGHSGTSCFLGTLDATVAEKGDSGEALLVFDLSGAVLDEAIAAVGHIPLPPYIASKRPEDERDRKDYQTVYAREEGAVAAPTAGLHFTPDLLEKIKARGIEEHFVTLHVGAGTFLPVKADDTGDHKMHAEIGHVSQRTASALNAVHERGGRIICVGTTSLRLIESATGEDGVVRPWSGATDIFITPGYRFRAVDLLMTNFHLPRSTLFMLVSAFSGLDTMHAAYNYAIADGYRFYSYGDASLLERIDHDRHSA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOB1A_XENLA
Sequence: MASSENEPFCVKFIKSPENSEYFFKAYEAIKQIQSDESLQLTEEREALLLKEKDKSLYICDPFSGAAFSHLKKLGCRIVGPQVVIFCMENQRRVPRAEYPVYNMAMADVTISCTSLDKETREDVHHYVQIMGGCVYRDLNVSVTHLIAGEVGSKKYLVAASLEKPILLPSWVKELWEKSNQRIIRYSDVNMTEYLCPIFRGCTICVTGLSSLDRKEVQRLTALHGGEYTGQLKMNESTHLIVQEAKGQKYECARKWNVHCISVQWFFDSIEKGFCQDETMYKIEPASTIKSVPDTSTPTGGNSKPNSRTLYDVSQISNISTSCVNESAFNSAMASRLDPPADTLENLDISSLQAPDDLLDGCRIYLCGFGGRKLDKLRKLINNGGGVRFNQLTGDVTHIIVGETDEELKQFLNKTQHRPYVLTVKWLLDSFAKGHLQPEEIYFHSSYQQTEMPSPFEPAINLTANKMSSTRDPLNHTRNHQADEDLLSQYTENNSTLIEDEHPKTSNTNSISQMSMHEDMTTCTSQSGLADTSTIIEGGLFSRKQFMVLGFLEEDEACIIDIIKKSAGKVLSSQKRAIADYAVVPLLGCEVESTVGEVVTNAWLGMCIEQEKLLDPHSNALFTPVPFLEGSTPLRECVLSVSQFMGAERDSLVYLAGLLGAKVQEFFVRKANPKKGMFASTHLVLKDAEGSKYEAAKKWNLPAVTMNWLLQCARTGRKADEDSYLVDNVPEEDKDESFISQTYKPQAIRLSMHAPCHLENHPEALTKAAVTPLDMNRFKSKAFQSVISQHNKNPQTSGGESKVLQREPSLHLDTPSKFLSKDKLFKPSFDVKDALAALETPGGPNQKNRTQSTPLSEVIGRNLQLAIANSTRQTAAVTASPQLKAAEKKEFDNSKLLINVVICVSKKLIKKQGELNGIAASLGAEYRWCFDESVTHFIYHGRQNDMSREYKSVKERSGIYIVSEHWLFACSEQQKRVPEALYPHTYNPKMSLDISAVQDGSYTASKFSADTSLQQDENSELQLQQNNKFGETSDDQVKKAAGDGNPQNPSKDVKGALTQTLEMRENFQRQLQEFMSATSVVKPRGSVGRAGFDNSPCTPEGARSTRNGRSRVLEALRQSRQAMTDLNTEPSQNEQIIWDDPTAREERAKLVSNLQWPDSPSQYSEQLQHNMNDAGGNYTPAKESLTDTEIAELEACEFEPKSAMRTPVIENNLQSPTKPDHLTPTPQAPSIAFPLANPPVAPQPREKPVQPFSKEETLKERRFQLSSLDPQERIDYSQLIEELGGVVIEKQCFDPSCTHIVVGHPLRNEKYLASMAAGKWVLHRSYLEACRAAKRFIQEEDYEWGSMSILSAVTNINPQQRMLAEAAMRWRKKLQGIKQNMGIAEGAFSGWKVILNVDQTKEPGFKRLLQSGGAKVFAGHSSPLFKEASHLFADFSKLKPDEPRVNVAEAAAQGVNCLKPEYIADYLMKELPPPMNNYCLPDAIPYVRVTGTGLSRKRKTSGDVSDVKRSRHY
What is the function of this protein?
Has dual roles in initiation of DNA replication, and regulation of checkpoint responses.  Required for DNA replication initiation but not for the formation of pre-replicative complexes or the elongation stages.  Necessary for the loading of replication factors onto chromatin, including gemc1, cdc45, DNA polymerases and components of the GINS complex such as ginsl/sld5.  Binds chromatin in both S-phase cyclin-dependent kinase (S-CDK)-independent and S-CDK-dependent modes.  Chromatin binding is required for the action of S-CDK, which in turn triggers the formation of preinitiation complexes of DNA replication.  Its role in checkpoint activation is independent of the DNA replication role.  In response to DNA damage, triggers the recruitment of checkpoint signaling proteins on chromatin, which activate the chek1 signaling pathway and block S-phase progression.  Increases the kinase activity of atr to numerous substrates, and is required for the phosphorylation of Rad1.
What are the official names of this protein?
DNA topoisomerase 2-binding protein 1-A, Cut5 protein, DNA topoisomerase II-binding protein 1-A, TopBP1-A, XtopBP.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Chromosome. Note=Associates with chromatin.
Protein: RU1C_ARATH
Sequence: MPRYYCDYCDTYLTHDSPSVRKQHNAGYKHKANVRIYYQQFEEQQTQSLIDQRIKEHLGQTGGYQQVGAVFNQHMLARPRPPMMLPPGSMPMGMRPPVLPRPMMPPQGYMPPPGVPQMMAPPGAPLPPPPQNGILRPPGMAPIPGQGGGPPGMAPIPGQGGGPPPNYNGLPPPPPYHTNPAAPPSGNFNNPNLNNPNPSAESPESNE
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LYSZ_AERPE
Sequence: MARYGVAVVKIGGSIASRLERVADEIAVLAREGLRLVVVHGGGKVVDEYSRRMGVEPRYVLHPSGVRSRYTSWEELEVYVMVMAGLLATSISSELASRGLKVLSLTGLDGLSVEARRRERIVIVNERGRPQAIPGGYTGKIERVDSMFVGSMLQQVDVILYSPVAYGREGDRVVALNVDGDQMAASLSAALKAPLALVTDVPGVILDGRVVDRIRVSEAREIAAKAGVGMNRKILMAAKAVSEGSPYAAIGDPPIQSLINGEKGTLVTRS
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.  Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
What are the official names of this protein?
Putative [LysW]-aminoadipate/[LysW]-glutamate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. LysZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_BART1
Sequence: MAVPKRKTSPAKRGMRRSADALKAPTYIEDKNSGELRRPHHIDLKTGMYRGRSVLVVKD
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MBHM_SHIFL
Sequence: MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEIVKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESALNIDVPVNAQYIRNIILAAHTTHDHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVASGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNLAVGGVANPINLDGLGVLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRGKGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSDEYLIKGIQESAKHSWYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRESTQNKLNEIVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNIGKGDHTTFVKPNIPATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGPRNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKVL
What is the function of this protein?
This is one of three E. coli hydrogenases synthesized in response to different physiological conditions.  HYD2 is involved in hydrogen uptake (By similarity).
What are the official names of this protein?
Hydrogenase-2 large chain, HYD2, Membrane-bound hydrogenase 2 large subunit, NiFe hydrogenase.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PBP1_ARATH
Sequence: MASPKSSTRPNQENQEPQFQDFFPTMAGKLGGEGLIEEICKGFELLMDKDKGVITFESLRRNASTVLGLGDLTDDDVRYMINEGDFDRDGALNQMEFCVLMFRLSPELMEASRCVVTEVIEEEFYRH
What is the function of this protein?
Potential calcium sensor that binds calcium in vitro.
What are the official names of this protein?
Calcium-binding protein PBP1, KIC-related protein 2, PINOID-binding protein 1.
Protein: LIAS_MEDTR
Sequence: MMYSRFRTVAKNLKSTTKPFSFTTATTTTTVSSSEFPQNLTELRARLARESPSLSDFISLKSNNAYSVEVGTKKNPLPKPKWMKESIPGGWKYVQIKKKLRELKLHTVCEEAKCPNMGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPPPDPDEPTNVAEAIASWGLDYVVITSVGRDDLPDQGSSHFTETVQKLKILKPSILIEALVPDFRGNAECVEKVSKSGLDVFAHNIETVEELQSAVRDHRANFNQSLDVLRMAKDYAPAGTLTKTSIMLGCGETPDQIVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVSEYITPEAFEKYQTLGMEMGFRYVASGPMVRSSYKAGEFYIKSMIDSDRAVSSQS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: THII_ECOSE
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQLEGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTEQEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNRTWLLWCERGVMSRLQALYLREQGFNNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARA_LACLA
Sequence: MSKRLLILEDGTIFEGESLGANLDVTGELVFNTGMTGYQESITDQSYNGQILTFTYPIVGNYGVNRDDYESIHPTCKAVVVHEAACRPSNWRMQMSFDEFLKAKNIPGITGVDTRAITKIVREHGTMKASLVQARDEVEHQMSQLQATVLPTNQVETSSTTTAYPSPNTGRKVVVVDFGLKHSILRELSKRECNLTVVPYNTSAQEILEMEPDGVMLTNGPGDPTDVPEAIEMIKEIQGKIPIFGICLGHQLFSLANGAKTYKMKFGHRGFNHAVREIATGRIDFTSQNHGYAVSSENLPEDLMITHVEINDDSVEGVRHKHFPAFSVQFHPDAAPGPHDASYLFDDFMDLMDNFKK
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: PSBF_CHAGL
Sequence: MTIDRTYPIFTVRWLAIHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: COX2_BOSTR
Sequence: MAYPMQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLSFDSYMIPTSELKPGELRLLEVDNRVVLPMEMTIRMLISSEDVLHSWTVPSLGLKTDAIPGRLNQTTLMSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKYFEKWSASML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CZS6_CRUCA
Sequence: MAYLKKSLFLVLFLGLVSLSICEEEKREEENEEEQEDDDQSEEKRGFLDVITHVGKAVGKAALNAVTEMVNQAEQ
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Cruzioseptin-6, CZS-6.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Cruzioseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GALA_PSEPK
Sequence: MADEGGNPRDLPPVGGHAALSRHIGQSLMADEFDMSFFRDKPLDHGFFSPMSALLPCDESWPVQIVPLQVGVLQLPIPTARRCYKLGQALRRAIESYPEDLKVAIVATGGVSHQVHGERCGFNNPEWDAQFLDLLVNDPQRLTEMTLAEYATLGGMEGAEVITWLIMRGTLSANVERKHQSYYLPSMTGIATLLLENRDQALPAPVNERHRQHMQHQLAGAEQLEGTYPYTLERSAKGYRLNKFLHRMIEPQWRQRFLSEPEALYREAGLSEEESDLLRRRDWRGLIHYGVIFFVLEKLGAVLGVSNLDIYAAMRGQSIEDFMKTRNQQVRYSVAGKAPN
What is the function of this protein?
Ring-cleavage dioxygenase that acts specifically on gallate to produce the keto-tautomer of 4-oxalomesaconate.  Mediates the first step of gallate degradation pathway.
What are the official names of this protein?
Gallate dioxygenase, Gallate degradation protein A.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: TAM_ENT38
Sequence: MADWNPSLYLQYGAERTRPAAELLARIALDDVSDLLDLGCGPGNSTALLLKRWPLARITGVDNSPAMLEQARVAVPECRFIEADVRQFKPEHAVDLIYANASLQWVPDHYALLPHLISLLKLNGVLAVQMPDNVDEPSHVLMREVAYEQGYPNRAREPLPGIHAYYDILTETGCDVDIWRTTYYHKMSSHQAIIDWVSATGLRPWMQELSEHEQLKFLERYHELLVQQYPIQENGQILLAFPRLFFVARREP
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.