PharMolix/UniProtQA huggingface dataset:
Protein: DER_COXBU
Sequence: MLPVIAIVGRPNVGKSTLFNYLTKSRAALVADVPGVTRDRQYGETTIDSQRLLLVDTGGLVDTENKEVAPLAETQVEQAIDESDCILFLVDAKAGLVPADEIIAERLRKKGKKIFLAVNKADRARAAVVQSDFYKLGFGEPYVIAAASGRGVKDLMTQVLENLPEEKEVIEKEVGIKIAMIGRPNVGKSTLINRLLGEERVIVYDQPGTTRDSIYIPFARNDENYTLIDTAGIRRRAKIQDYVEKFSMIKSLQAMHAADVVIFLLDARQGVTEQDLRLLNRIVEAGVSLIIAVNKWDGLNIEERDNVRNAIDRRMPFVDFARRYFISALHGTGVGKLFRAIQESYQSIQQELTTGQLTRALEKAVAEHEPPLVKGRRIRLRYAHLGARHPLTIVVHGKQTKSLPQSYSRYLANYFRKTFNFIGVPVHIKLKTDPNPYEGQEER
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: Y064_RICTY
Sequence: MKKLLLAASIIYFASVSLAEEKTTPFISNSDTKIKLEGFYLFESGYIKQDHLILFDKNVTDNRKKLGFDTEVAFAATITKTIDDVIAGAKIVLQPTTKAKTTASYNGSHIFIETSYGKVELGSPVDASAQLRVTGNKVTAGTGGWYRYALLDGQYMRYNALKPDFDTSVNFYLESYSNSFDQVNEKTEKARRLNFFTPKMKGFQAGISYTPDTANTGGNKNINNLTLQSSGRNGISASRTGIKTLSIANGEIMTINQNIRDAFSAGLTYEHAISEDADLKLSMTGEYGKPARRLIHAKVDGTTKAIEVLNTYKLSNLKAYNLGAVFTYGNFSCGASYGNLGKSLTAKEYYKVGRNTYYYNGAVAYGQGPIKTSLAYLKTSRYKNTVNAVSLATEYKIMPGLLPYAEISHFQAKGKPVYYPEAPSKTTRGTVGLIGTKLKF
What are the official names of this protein?
Uncharacterized protein RT0064.
Protein: ATPA_PSEMY
Sequence: MQQLNPSEISEIIKQRIESLDVTAQARNEGTIVSVSDGIVRIYGLADVMYGEMIEFPGGVYGMALNLEQDSVGAVVLGSYLTLAEGMSAKCTGRILEVPVGPELLGRVVDALGNPIDGKGPINAAASDAVEKVAPGVIWRKSVDQPVQTGYKSVDAMIPVGRGQRELIIGDRQIGKTALAVDAIINQKDSGIRCVYVAIGQKQSTIANVVRKLEEAGALANTIVVAASASESAALQFLAPYAGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVSEEYVEKFTNGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESAMFNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDEATRKQLEHGQRVTELMKQKQYAPMSIAEMSVSLYAAERGFLQDVEVAKVISFEQALIAFFKRDHADLMAKINEKGDFNDEIDAGLKAGIEKFKATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLME_METBU
Sequence: MARDRRDTYYWRAKDEGYRSRAAYKLFQINEKHEVIKEDDTIVDLGAAPGGWLEVAKKISGGKIVGVDLRRIKEIEGVETIKGDITSDETIKKIIELVGEGGADVVICDAAPNLSGNWSLDHARSIDLTTSALECAKKILKPKGHFIVKVFQGDMFKEYMDKVRESFTYTRAFSPKASRPESAEIYVIGKKLLTAPLKIDDKFDVTIKKIGAKGNGIAFVEDFVVFMQDEVKKGENVRIKIVDVKPEFAFAIVIGRYDEELNEKNEE
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRC19_YEAS6
Sequence: MRKPSITITTAKAIITPDYTLIKSHSKYQLPSRFQKLDADSPERSTVVKLFYRRFMRLKPFISNVKMVKDTYRDYVRYKFMKENYELKRYLVFNPDGLRSKIKVELLSNTKCCEKILPVTEMQRTLEFVLKSCSYLPETKAQKWDIARDNTYCRQILKNLLTMQYEKYRSILHRGIGHDELDVKFSHLKTTSSPLTKLNKTEKKKIPLFKVFSDFDTTLIYLNETLGTRL
What is the function of this protein?
Involved in sporulation and maintenance of the mitochondrial DNA.  Is probably involved in a pathway contributing to genomic integrity (By similarity).
What are the official names of this protein?
Increased recombination centers protein 19.
What is the protein family that this protein belongs to?
Belongs to the IRC19 family.
Protein: NEP_I36A0
Sequence: MDPNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVRHKLKVTENSFEQITFMQALHLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: SSB1_STRP6
Sequence: MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGEREADFISVVVWGKLAETLVSYASKGSLMSIDGELRTRKYDKDGQVHYVTEVLCQSFQLLESRAQRAMRENNVTNDLVDLVLEEDTLPF
What are the official names of this protein?
Single-stranded DNA-binding protein 1, SSB 1.
Protein: IHFB_ACTP2
Sequence: MTKSELIENLVSLNPALQVKSVEDGVKEILEQIMLFLERGERVEVRGFGSFSLHYRQPRVGRNPKTGESVKLDAKYVPHFKAGKDLKERVDLV
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: NDPA_ECOUT
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELHRVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGFVLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADRSTLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGGN
What are the official names of this protein?
Nucleoid-associated protein YejK.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DNAJ_RHIEC
Sequence: MAKADFYETLGVAKSADEKELKSAFRKLAMKYHPDKNPDDKEAERKFKEINEAYEMLKDPQKRAAYDRYGHAAFEHGGMGGGGGGFAGGGFSDIFEDIFGEMMGGGRGRQRSAGGRERGADLRYNMEITLEEAFSGKTAQIRVPTSITCDVCSGSGAKPGTQPKNCGTCQGTGRVRAAQGFFSIERTCPTCHGRGQIIPDPCPKCHGQGRVTEERSLSVNIPAGIEDGTRIRLQGEGEAGTRGGPAGDLYIFLSVKPHEFYQRDGADLYCAVPISMTTAALGGTFDVATLDGTKSRVSVPEGTQAGKQFRLKGKGMPVLRSAQTGDLYIQIQIETPQKLTKRQRELLQEFEQISSKENNPESTGFFARMKEFFEG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI1_BACHK
Sequence: MEYKNTLLMPKTEFPMRGNLPKREPAMQEKWAEMNIYEKVQEHTKGRPLFVLHDGPPYANGDIHMGHALNKVLKDFIVRYKSMTGFCAPYVPGWDTHGLPIEQALTNKGVKRKEMTVAEFRKLCAEYAYEQVERQREQFKRLGVRADWDNPYITLEPAYEAQQIKVFGDMAKKGYIYKGQKPVYWSPTSESALAEAEIEYQDKKSASIYVAFPVKDGKNVLEGDEKYIIWTTTPWTLPANLGISVHPELEYAIVKVNDEKYIIASELFETVAKTLEWENAEVVKTVKGSELEYTVAKHPFYDRDSLVMLGDHVTTDAGTGCVHTAPGHGEDDFVVGKKYGLEVLCPVDDKGVLTEEAPGFEGLFYDKANKPITEKLEEVGALLKLTFITHSYPHDWRTKKPIIFRATAQWFASIEAFRKELLEAVAETKWVPAWGETRLHNMVRDRGDWCISRQRAWGVPIPVFYAENGDPIITDETINHVADLFREHGSNVWFEREAKDLLPEGFTHPGSPNGEFRKETDIMDVWFDSGSSHQAVLEERDDLQRPADLYLEGSDQYRGWFNSSLSTAVAVTGKAPYKGVLSHGFVLDGEGRKMSKSIGNIVVPKKIMDQLGGDILRLWVSSVDYQSDVRISDDILKQVAEVYRKIRNTFRFLLGNLDDFKPSENTVAVAELREVDRYMLVKLNDLITKVKEAYETYDFAAVYHAIHNFCTIDLSSFYLDFAKDILYIEGANHEDRRAIQTVLYDVLVALTKLVTPILPHTADEVWPYIPGVTEESVQLTDMPEAVQLDDAEALKTKWDAFMTLRDDVLKALEVARNEKVIGKSLNASITLYPTAEMKAMLESINEDLKQLFIVSEYKLGGMMEEAPADAPKYEHTAVVVAQATGETCERCWVVSETIGKDAEHETLCERCATVVKENYVK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase 1, Isoleucyl-tRNA synthetase 1, IleRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP48_NPVOP
Sequence: MHTYKLLYNLRFNAVHGLEHRFEHVRFEAQMHQREIDSLTFLTAKYFDQHSLIDIKGLTFFTEFNKCIVAIKAKFEAQPDSENLHGIKSIMGMFLRDEFIKQVPHFKTIMEYLKTYYNPIAVPDVRAFMCDEQCRPGGKISCLTCKCNYLSAALTTLDSGLQDGWDIFLRPMFGMPLLIYVISKTDFSSQPDVVNENNLMTQMFVQFFYNLLCDKAYSMHTKQKACEPLVKDCKRVITLLSAKDRHRLLTMLNEQCNSASTAANAPKLLMPFKNFMIKMGQHTKIKKVNKIAATVLIGFFLRQYIESMPSHYLQNLRGLLKDEHNDSRDEGCSAAELEMLNVCRYIFKRYSDKDVAVVVEKLKKITVEIMNVLIFEKIVPETFIRRIIVDYQLDNEISLLLDLNHDCFDRR
What are the official names of this protein?
p48 protein.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae p48 family.
Protein: SYCC_XENTR
Sequence: MTDSWERGKGRRTQPPWSAPNTQAQPGLRLYNSLTRSKELFVPQDGNKVTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFKYDVFYCMNITDIDDKIIKRARQRHLFQQYRERNPRPSDLLQDVSAALTPFLQRISEANDPDKRQMLERIHGSVSAALLPLQDAVSSNARAEELERLSQELMEAAVDLLSDWLDEKHGAQITDNSIFSQLPKHWESEYHRDMEALNVLPPDVLTRVSEYVPEIVAFVQRIVDNGYGYVSNGSVYFSTAKFHASEKHYYAKLVPEAVGDQKALQEGEGDLSISADRLSEKQSPNDFALWKASKPGEPSWESPWGKGRPGWHIECSAMAGSILGESMDIHGGGFDLRFPHHDNELAQSEAYFDNDHWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALQKNTARQLRLAFLMHAWKDTLDYSSNTMESAVQYEKFMNEFFLNVKDLLRAPTDVTGQFVKWEVPELELNSCFYSKKAAVHEALCDNIDTRTVMEEMRSLVSQCNSYIASRKAAKQPPNRLLLRSVSSYLTAMLKVFGAIEGEEVIGFPIGGSDNSMNLESTVMPYLQVLSQFREGVRQIARQHKVTEVLQLSDLLRDDVLPELGVRLEDHEGLPTVVKLVDRETLLKEKEEKRKAEEEKQRKKEEAARKKQQQEAAKLEKMKVSPSQMFQLETDKYSQFDESGFPTHDTEGKELSKGQSKKLRKLYEAQEKLHKEYLQMAQNGTTG
What is the function of this protein?
Catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).
What are the official names of this protein?
Cysteine--tRNA ligase, cytoplasmic, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISAHY_ROSAI
Sequence: MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA
What is the function of this protein?
Involved in the degradation of the plant hormone indole-3-acetic acid (IAA).  Catalyzes the hydrolysis of the cyclic amide bond (lactam) of isatin (1H-indole-2,3-dione) to yield isatinate (2-(2-aminophenyl)-2-oxoacetate).
What are the official names of this protein?
Isatin hydrolase, Isatin amidohydrolase, Isatin hydrolase isoform b, IH-b.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily.
Protein: PROB_BURCJ
Sequence: MRSIIADSKRLVVKVGSSLVTNDGKGLDHAAIGRWAAQIAALRAQGKEVVLVSSGAIAEGMQRLGWSKRPREIDELQAAAAVGQMGLAQVYESRFTEHGIRTAQILLTHADLADRERYLNARSTLLTLLRLGVVPIINENDTVVTDEIKFGDNDTLGALVANLIEGDALIILTDQSGLFTADPRKDPNATLVGEANAGAPELEAMAGGAGSSLGRGGMLTKILAAKRAAHSGANTVIASGREADVLVRLAAGEAIGTQLIARTARMAARKQWMADHLQVRGHVVIDAGAVEKLTAGGKSLLPIGVIDVQGAFARGEVIACVGPDGREVARGLTNYSSAETKLIHRKPSGEIETVLGYMLEPELIHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CADA1_STAAU
Sequence: MSEQKVKLMEEEMNVYRVQGFTCANCAGKFEKNVKKIPGVQDAKVNFGASKIDVYGNASVEELEKAGAFENLKVSPEKLANQTIQRVKDDTKAHKEEKTPFYKKHSTLLFATLLIAFGYLSHFVNGEDNLVTSMLFVGSIVIGGYSLFKVGFQNLIRFDFDMKTLMTVAVIGATIIGKWAEASIVVILFAISEALERFSMDRSRQSIRSLMDIAPKEALVRRNGQEIIIHVDDIAVGDIMIVKPGEKIAMDGIIVNGLSAVNQAAITGESVPVSKAVDDEVFAGTLNEEGLIEVKITKYVEDTTITKIIHLVEEAQGERAPAQAFVDKFAKYYTPIIMVIAALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCALVISTPISIVSAIGNAAKKGVLVKGGVYLEKLGAIKTVAFDKTGTLTKGVPVVTDFEVLNDQVEEKELFSIITALEYRSQHPLASAIMKKAEQDNIPYSNVQVEEFTSITGRGIKGIVNGTTYYIGSPKLFKELNVSDFSLGFENNVKILQNQGKTAMIIGTEKTILGVIAVADEVRETSKNVIQKLHQLGIKQTIMLTGDNQGTANAIGTHVGVSDIQSELMPQDKLDYIKKMQSEYDNVAMIGDGVNDAPALAASTVGIAMGGAGTDTAIETADIALMGDDLSKLPFAVRLSRKTLNIIKANITFAIGIKIIALLLVIPGWLTLWIAILSDMGATILVALNSLRLMRVKDK
What is the function of this protein?
Couples the hydrolysis of ATP with the export of cadmium (PubMed:1530844).  Involved in cadmium resistance (PubMed:2524829, PubMed:1530844).
What are the official names of this protein?
Cadmium-transporting ATPase, Cadmium-efflux ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM1_SYNJA
Sequence: MFIAVVGLSHRTAPVEIRERLSIPEAEVGERIQQLRAHPHIEEAAILSTCNRLEVYIVTPEMESGVRQTMQFLAEAKGIPLPQLRPHLFTLLYQDAVTHLMRVAAGLDSLVLGEGQILSQVKKAQQLGQACNGMDRILNRLFKAAITAGKRIRTETGIGTGAMSISSAAVELALQEQGSLSQGKVTVVGAGKMARLLVQHLLAKGAVDITVVNRSLERAEALAKQFEQPIQVLPWESLLSSIAESNLVFTSTGATQPILTYEQLAGVLQPDQPLLLVDISVPRNIDPGVEKLRGVQVFNVDHLSRIVEENRAQRQKLALAAEALVEEEVEQFMEWWRSLETVPTISSLRHKVESIREQEMEKALSRLGKDFAEKHLEVIEALTRGIVNKILHDPMVQLRAQRDIEARRRAMQILQELFNLDPMPFQAQQER
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RUVA_EXISA
Sequence: MIEFVKGPVAYVCAEYITLDVSGVGYKVHVPNPFFYREQDEHVIVFTHHYVREDQQTLYGFRSRRERELFNKLLSVSGIGPKGALAIVASGDIDALIDAIETENEKYLTKFPGVGKKTAKQMALDLKGKLSELAPDYVPNEGLFAQGASELDEACEALVALGYSEREIAKVRKALSGEILTTDAYIKRALQLLLK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RUVA_SYNE7
Sequence: MIGYLQGSLAGVRKQSGRLLLLLDVQGVGYEVQTPARSLVELPAAGQSLQVFTHLQVREDQWLLFGFLQMAERDLFRQLISVSGIGPQLGLALLDSLSLAELVQAIVAGNTRLLSRTPGVGAKTAERLALELRSKLAEWREEAGLLPSATAAPIAAVQEDVEMTLLALGYNNREILQALTAIAQENLVQSGQPAEDWIREAIAWLSR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: WHIA_STRGG
Sequence: MAMTPAVKNEISHLPVTRTCCRKAEVSAILRFAGGLHLVSGRIVIEAELDTGNAARRLKRDILEIFGHSSELIVMAPGGLRRGSRFVVRVVAGGDQLARQTGLVDGRGRPIRGLPPQVVSGATCDAEAAWRGAFLAHGSLTEPGRSSSLEVTCPGPEAALALVGAARRLSIAAKAREVRGVDRVVVRDGDAIGALLTRLGAHDAVLAWEERRMRREVRATANRLANFDDANLRRSARAAVAAGARVGRALEILGEEVPEHLAAAGRLRMEHKQASLEELGALADPPLTKDAVAGRIRRLLAMADKRAQDLGIPGTESTLSEELADGLVG
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RL34_XANP2
Sequence: MKRTYQPSKLVRKRRHGFRARMATRNGRKIIAARRNHGRQRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: Y7102_PARPJ
Sequence: MLLHIPNVLNAEQLRLVRERLDQAGDAWVDGRATAGYQGAPVKRNQQIAEHTPVARELGDVILASIERNPLFISAVLPNQVYPPLFNRYEGGMQFGSHVDGAVRVLPNGVKLRTDVSVTLFISDPADYDGGELVIEDTYGVQQVKLPAGDMIVYPATSLHQVTPVTRGARIASFFWVQSLVRSDTQRAMLFDMDTAIQRLNASHADDTARRSLVGIYHNLLRTWSET
What are the official names of this protein?
PKHD-type hydroxylase Bphyt_7102.
Protein: C10_XENLA
Sequence: MSSLQRTAPASQAVSLPLEQVKEALGEVLNALQSPTGSARLEEARENSGNDLGKVLQLLLPAAVQIQQEVLQNYGFSADGEGVLRFARLVKSYESQDPEIAAMSSKLKSFFLPPLPLPPHAGLSAPSS
What are the official names of this protein?
Protein C10.
What is the protein family that this protein belongs to?
Belongs to the UPF0456 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR7_HUMAN
Sequence: MAGNSLVLPIVLWGRKAPTHCISAVLLTDDGATIVTGCHDGQICLWDLSVELQINPRALLFGHTASITCLSKACASSDKQYIVSASESGEMCLWDVSDGRCIEFTKLACTHTGIQFYQFSVGNQREGRLLCHGHYPEILVVDATSLEVLYSLVSKISPDWISSMSIIRSHRTQEDTVVALSVTGILKVWIVTSEISDMQDTEPIFEEESKPIYCQNCQSISFCAFTQRSLLVVCSKYWRVFDAGDYSLLCSGPSENGQTWTGGDFVSSDKVIIWTENGQSYIYKLPASCLPASDSFRSDVGKAVENLIPPVQHILLDRKDKELLICPPVTRFFYGCREYFHKLLIQGDSSGRLNIWNISDTADKQGSEEGLAMTTSISLQEAFDKLNPCPAGIIDQLSVIPNSNEPLKVTASVYIPAHGRLVCGREDGSIVIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICSVASDHSVGLLSLREKKCIMLASRHLFPIQVIKWRPSDDYLVVGCSDGSVYVWQMDTGALDRCVMGITAVEILNACDEAVPAAVDSLSHPAVNLKQAMTRRSLAALKNMAHHKLQTLATNLLASEASDKGNLPKYSHNSLMVQAIKTNLTDPDIHVLFFDVEALIIQLLTEEASRPNTALISPENLQKASGSSDKGGSFLTGKRAAVLFQQVKETIKENIKEHLLDDEEEDEEIMRQRREESDPEYRSSKSKPLTLLEYNLTMDTAKLFMSCLHAWGLNEVLDEVCLDRLGMLKPHCTVSFGLLSRGGHMSLMLPGYNQPACKLSHGKTEVGRKLPASEGVGKGTYGVSRAVTTQHLLSIISLANTLMSMTNATFIGDHMKKGPTRPPRPSTPDLSKARGSPPTSSNIVQGQIKQVAAPVVSARSDADHSGSDPPSAPALHTCFLVNEGWSQLAAMHCVMLPDLLGLDKFRPPLLEMLARRWQDRCLEVREAAQALLLAELRRIEQAGRKEAIDAWAPYLPQYIDHVISPGVTSEAAQTITTAPDASGPEAKVQEEEHDLVDDDITTGCLSSVPQMKKISTSYEERRKQATAIVLLGVIGAEFGAEIEPPKLLTRPRSSSQIPEGFGLTSGGSNYSLARHTCKALTFLLLQPPSPKLPPHSTIRRTAIDLIGRGFTVWEPYMDVSAVLMGLLELCADAEKQLANITMGLPLSPAADSARSARHALSLIATARPPAFITTIAKEVHRHTALAANTQSQQNMHTTTLARAKGEILRVIEILIEKMPTDVVDLLVEVMDIIMYCLEGSLVKKKGLQECFPAICRFYMVSYYERNHRIAVGARHGSVALYDIRTGKCQTIHGHKGPITAVAFAPDGRYLATYSNTDSHISFWQMNTSLLGSIGMLNSAPQLRCIKTYQVPPVQPASPGSHNALKLARLIWTSNRNVILMAHDGKEHRFMV
What are the official names of this protein?
WD repeat-containing protein 7, Rabconnectin-3 beta, TGF-beta resistance-associated protein TRAG.
Protein: TFE_METAC
Sequence: MNTLVDLNDKVIRGYLISLVGEEGLRMIEEMPEGEVTDEEIAAKTGVLLNTVRRTLFILYENKFAICRRERDSNSGWLTYLWHLDFSDVEHQLMREKKKLLRNLKTRLEFEENNVFYVCPQGCVRLLFDEATETEFLCPMCGEDLVYYDNSRFVSALKKRVDALSSV
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: SYH_NOVAD
Sequence: MSTQTPQPIRGTQDIFGPDAEAFAFVVETFERVRKLYRFRRVEMPVFEKTAVFSRSLGETTDVVSKEMYSFEDRGGESLTLRPEFTAGIARAYLTDGWQQYAPLKVATHGPLFRYERPQKGRYRQFHQIDAEIIGAGEPQADVELLVMADQLLKELGIGANDPGAVTLQLNTLGDGASREAWRAALVEYFRAHKAELSEDSQDRLERNPLRILDSKDPRDKPFTADAPRIDDFLSAEAQDFFGKVTSGLDAAGVEWTRAPALVRGLDYYRHTAFEFVTDRLGAQGTVLGGGRYDGLMEALGGAATPAVGWAAGIERLAMLVGEKGEARTDVIVVVEDDALLTSGIEQVSRLRREGVSAELVASGSARKRFDKAVKMGAKAILALAMRDGQPAARFRVEDDAATALRGQLEAAVAKYGAQ
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FENR_LACLM
Sequence: MQELDLIIVGAGPVGLYAAFYAGMRGLSVAIIESAQVAGGQPQNLYPEKLIYDIAGLPAVTGADLTKNLLEQLAQISHRLFLGEGVQKIEKEDGIFSVITDKSNRKAKAVLLTTGAGLLKPRKLGIDNEENLANEGKISYFITSLKEFEGKNVAVFGGGDSALDWSLMLEKVAKEVHLVHRRTAFRGHEMTVDRVMDSGIQVHTPYTFSNFNENDLELKKVKAEENLNFSIDKILVNYGFLTNQVSLAENLEVSRNGRVKADSMMQSNIEGLYVAGDASDYAGKMPLMSVGFGEAVHAINAMTKNLEFNHPLRGGHSSSIF
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: FOXP2_PANPA
Sequence: MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSTTSKASPPITHHSIVNGQSSVLNARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
What is the function of this protein?
Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium.  May also play a role in developing neural, gastrointestinal and cardiovascular tissues.  Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential.  Plays a role in synapse formation by regulating SRPX2 levels (By similarity).
What are the official names of this protein?
Forkhead box protein P2.
What are the subcellular locations of this protein?
Nucleus.