PharMolix/UniProtQA huggingface dataset:
Protein: ESAA_STAAM
Sequence: MKKKNWIYALIVTLIIIIAIVSMIFFVQTKYGDQSEKGSQSVSNKNNKIHIAIVNEDQPTTYNGKKVELGQAFIKRLANEKNYKFETVTRNVAESGLKNGGYQVMIVIPENFSKLAMQLDAKTPSKISLQYKTAVGQKEEVAKNTEKVVSNVLNDFNKNLVEIYLTSIIDNLHNAQKNVGAIMTREHGVNSKFSNYLLNPINDFPELFTDTLVNSISANKDITKWFQTYNKSLLSANSDTFRVNTDYNVSTLIEKQNSLFDEHNTAMDKMLQDYKSQKDSVELDNYINALKQMDSQIDQQSSMQDTGKEEYKQTVKENLDKLREIIQSQESPFSKGMIEDYRKQLTESLQDELANNKDLQDALNSIKMNNAQFAENLEKQLHDDIVKEPDTDTTFIYNMSKQDFIAAGLNEGEANKYEAIVKEAKRYKNEYNLKKPLAEHINLTDYDNQVAQDTSSLINDGVKVQRTETIKSNDINQLTVATDPHFNFEGDIKINGKKYDIKDQSVQLDTSNKEYKVEVNGVAKLKKDAEKDFLKDKTMHLQLLFGQANRQDEPNDKKATSVVDVTLNHNLDGRLSKDALSQQLSALSRFDAHYKMYTDTKGREDKPFDNKRLIDMMVDQVINDMESFKDDKVAVLHQIDSMEENSDKLIDDILNNKKNTTKNKEDISKLIDQLENVKKTFAEEPQEPKIDKGKNDEFNTMSSNLDKEISRISEKSTQLLSDTQESKTIADSVSGQLNQLDNNVNKLHATGRALGVRANDLNRQMAKNDKDNELFAKEFKKVLQNSKDGDRQNQALKAFMSNPVQKKNLENVLANNGNTEVISPTLFVLLMYLLSMITAYIFYSYERAKGQMNFIKDDYSSKNHLWNNVITSGVIGTTGLVEGLIVGLIAMNKFHVLAGYRAKFILMVILTMMVFVLINTYLLRQVKSIGMFLMIAALGLYFVAMNNLKAAGQGVTNKISPLSYIDNMFFNYLNAEHPIGLALVILTVLVIIGFVLNMFIKHFKKERLI
What is the function of this protein?
Component of the type VII secretion system (Ess).  Provides together with EssB and other components such as EssC and EssE a secretion platform across the cytoplasmic membrane in the host.
What are the official names of this protein?
Type VII secretion system accessory factor EsaA.
What is the protein family that this protein belongs to?
Belongs to the EsaA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEFH2_CRAGI
Sequence: LLTLAVLLMVSADMAFAGFGCPGDQYECNRHCRSIGCRAGYCDAVTLWLRCTCTGCSGKK
What is the function of this protein?
Antibacterial peptide mostly active against Gram-positive bacteria (PubMed:20605792).  It acts by selectively inhibiting peptidoglycan biosynthesis through complex formation with the cell wall precursor lipid II (1:1 molar ratio) thus inhibiting cell wall synthesis (PubMed:20605792).  It does not disrupt cell membranes (PubMed:20605792).  Is noticeably more potent than Cg-Defh1 (PubMed:20605792).
What are the official names of this protein?
Hemocyte defensin Cg-Defh2.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: NSP5_ROTBS
Sequence: MSDFGINLDAICDNVRRNSSNSSIKSQVSNRSSRKMDFVDEDELSTYFNSKTSVTQSDSCSNDLNVKHSIIAEAVVCDESAHVSADAVQEKDVVVPKMDESVMKWMMDSHDGICVNGGLNFSKLKNKSNEHETKVTSETNVSAHVSAGINSQLGMFNPIQHKIKKEAIPEMFEDEDTDECTCRNCPYKEKYLKLRKKLKNVLVDIITEM
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: PEPE_SALAR
Sequence: MELLLLSNSTLPGKAWLEHALPLMANQLNGRRSAVFIPFAGVTQTWDEYTDKTAEVLTPLGINVTGIHRIAAPLEAIEKSEIIIVGGGNTFQLLKESRERGLLAPIADRVKRGALYIGWSAGANLACPTIRTTNDMPIVDPNGFDALGLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTVIGLPEGNWIQVSNGQAVLGGPNTTWVFKAGEEAVALEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_STRTM
Sequence: MNYQPTPEDRFTFGLWTVGWQGRDPFGDATRPALDPVEAVQRLAELGAYGVTFHDDDLIPFGSSDAEREAHVKRFRQALDATGMTVPMATTNLFTHPVFKDGAFTANDRDVRRYALRKTIRNIDLAVELGAKVYVAWGGREGAESGAAKDVRAALDRMKEAFDLLGEYVTSQGYDIRFAIEPKPNEPRGDILLPTIGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQSGIKYDQDLRFGAGDLRAAFWLVDLLESAGWEGPRHFDFKPPRTEDIDGVWASAAGCMRNYLILKERAAAFRADPEVQEALRAARLDQLAEPTAADGLQALLADRTAYEDFDVDAAAARGMAFERLDQLAMDHLLGARG
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADHS_AQUAE
Sequence: MGIGKEIRLERIMNRETRKTIIVPMDHGVSSGPIEGIVNIREAVEKVAEGGANAVVLHKGMVRAGHRGRGRDIGLIVHLSASTDLSPRKNDKVLVCTVEEAIRLGADAVSIHVNIGAEGEREMLKDFGYVSKVCEEWQMPLLAMVYGRGPKIENQYDPKVVAHCARVGAELGADIVKVPYTGDPETFKLAIEGSPIPVVIAGGPKMKSEREVLEMVQGAMQAGAAGLSIGRNIFQAKDPAKMVRAMSLIVHEGKSVEEAFEILK
What is the function of this protein?
Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH).  Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
What are the official names of this protein?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase, ADH synthase, ADHS, ADTH synthase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
Protein: YBEY_BORPA
Sequence: MATELSLSVQYGVADARLPRWRLRRWVQYALAGAAGDGHAGLAGAELGLRLVGLAEGRRLNREFRGRDYATNVLTFEYGTGPDGVARGDIVVCVPVLAREAREQRKTLLDHAAHLTVHGTLHALGYDHIKAGEARRMEALETVVLARMGIADPYLAA
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB8_ORYSJ
Sequence: MREILHIQGGQCGNQIGAKFWEVICGEHGVDPTGTYTGTSPQQLERINVYFNEASGGRHVPRAVLMDLEPGTMDSLRSGPIGGIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTNPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGRMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPVGLSMASTFVGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTSEGMDEMEFTEAESNMNDLVAEYQQYQDATAEDDYDEDDDAAAADEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-8 chain, Beta-8-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MOAA_RALSO
Sequence: MPAQGWLADTYGRRLHDLRISVTDRCNFRCIYCMPKDVFDKDYRFLQHSELLSFEEIERMVRLFIEHGVEKIRLTGGEPLLRKDIERLVEMLARLNTRDGKPLDLTLTTNGALLARKAQALKDAGLTRVTVSLDAIDDATFRRMNDVDFAVAEVLHGIEVAQRVGLAPLKINMVVKKGDNDDQIVPLARHFRNSGIILRFIEYMDVGVTNHWEMASVVPSAEVIRRLSAAFALEPLSANYAGETAERWRYADGAGEIGVISSVTQAFCHDCTRARLSTEGKLYLCLFATQGFDLRALLRGGASDLEVSNAIRTVWQARTDRYSELRASGTAPPTGRRIEMSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RL31B_HALHL
Sequence: MKKDIHPEYREVVFQDISTDFSFLTRSTVKTDETITWQDGNEYPLVKIEVSSRSHPFFTGKQRVVHSGGQVDRFRKRFGMTRGSSSQ
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: ATPE_SHEFN
Sequence: MAAKTVQLDIVSAENSIFHGQVSFLEVNGAEGELGIMPNHVALLTKIKPGMARFIKQDGSEEVLYLSGGLLEVQPTAISVLADVALRADDIDEKAALEAKERAEQAIANAGTDFNYEAATIELAKSLAQLRVVECIKKNITR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNAS1_PROGU
Sequence: KESSAKKFQRQHIDSSGSPSTNPNYCNAMMKSRNMTQERCKPVNTFVHEPLADVQAVCFQKNVPCKNGQSNCYESTSNMHITDCRLTSNSKFPDCLYRTSQEEKSIIVACEGNPYVPVHFDASVAASA
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNME_ECOLC
Sequence: MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPRYADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVRNKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDX1_PANTR
Sequence: MNGEEQYYAATQLYKDSCAFQRGPAPEFSAGPPACLYMGRQPPPPPPHPFPGALGALEQGSPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
What is the function of this protein?
Activates insulin and somatostatin gene transcription.  Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut.  As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element.  Binds the DNA sequence 5'-CC[CT]TAATGGG-3' (By similarity).
What are the official names of this protein?
Pancreas/duodenum homeobox protein 1, Homeodomain protein PDX1, Insulin promoter factor 1, IPF-1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. IPF1/XlHbox-8 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: BCHL_RHORT
Sequence: MFDETMRQPPDGEGSVQVEMDPALHIETAKVFAIYGKGGIGKSTTSSNLSAAFSKLGKRVVQIGCDPKHDSTFTLTKRLVPTVIDVLQAVHFHTEELRVEDFVYEGYNGVMCVEAGGPPAGTGCGGYVVGQTVKLLKEHHILEDADVVVFDVLGDVVCGGFATPLQHAERALVVAANDFDSIFAANRIAAAIQAKAKNYDVRLGGIIANRSVATDQIERFNARSGMRTLAHFPDLDVIRRSRLCKSTLFEMEPSPELAAVQQEYLRLAEALWEGVEPLTATPLIDREIFDLLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: RL37A_THEAC
Sequence: MSKRTVKVGVAGRFGPRYGVTIRKEWSEIYKQKIALYTCPSCKKKRVKRVANGIWQCRHCGYKFAGGSYTPAYEIKVVEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
Protein: AROE_CLOPS
Sequence: MKLFGLIGEKLGHSLSPEIHNKVFKDNNIDGLYNLFSVKKDFENNIVESLKCLGVRGANVTIPYKEKVMNQLDIISHEAKAIGAVNTILIKDGKSYGYNTDYYGFGKMLERAKVDIEGNSFFVLGAGGAARSILKYLEDSKAKKIVLVSRDKEKVFKKFKDFNINFMSYGELEEIHEEFALINTTPCGMYPNTNSVAVSEKVIKKFKVALDIVYNPLETKFLKMAKDNGLKTVDGLFMLVGQGVKAEEIWNGIKVDKSTEENIYEELKCRF
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: GSA1_EXISA
Sequence: MTTSSNRQSSDALYQDALTHIVGGVNSPSRSFKAVGGGAPVYMERGEGAYFYDVDGNRYIDYLAAYGPIITGHAHPHIHEALMNASSKGLLYGTPHRLEVEFAKKLKQAIPSMDKVRFTNSGTEAVMTTVRVARAYTGRELVVKFSGCYHGHSDLMLIAAGSGPATLGSPDSAGVTKATAKEVITVPFNDVEAYREMMKEWGDQVACVLVEPIVGNFGIVEPKPGFLQAVNDITHEHGALVIYDEVITAFRFTYGSAQQVYGIEPDMTALGKIIGGGLPIGAYGGKAEIMETVAPLGPAYQAGTMAGNPASMATGIACLEVLEQPGVYEKLDALGAKLEAGIREAAEKHDVTITLNRLKGALTVYFTDEIVTDYEGAEKSDGEKFGRFFKLMLENGVNLAPSKYEAWFLTTEHTEQDIEETIEAVNRSFAQL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APN1_PLAF7
Sequence: MFFSFYHSSFSSLSSFFFSFFSLLLYMLVLLQIFPKNYYEAGTLSIRVIRKNTFNHSYNNIKNIHYIHCGYPNIFNNCRNYYMNNFYNNNLSAPFKNKNNYMHIFFKIVEGNKKKKREHPFFKYLFHMNMLEKSGDKKNTVISKITESCQYGDIRKYMNMKKESLEEGEKNKSGEEYNKHVEQNNIKDEKIHFKDGTFIKSKEEEIENEKGGTICLKKEIQKNVLEINNNTYNNDTKYLSNPKGVTNKSKQSKKEIEKKKKKKNNNNNNNNNNKIKSEKSANDTKNIPPIPKNTEDRWNDYNKIKEYAKISNVYLGAHISASGGVQNAPINSFNISGLAFALFLKNQRKWESAALTNENIKQFEENCKKYNFDKNFILPHGSYLINLANPDKEKRDKSYLSFLDDIKRCEQLNIKLYNFHPGSTVGQCTVDEGIKNVADCINKVHKETNNVIIVLENSAGQKNSVGSKFEHLRDIINLVHDKDRIGVCLDTCHTFAAGYNIKTFENFDNVMKQFDDIVNVKYLKAVHLNDSKSDIGSGLDRHENIGKGKLTMDTFKYIMKSKYFKNIPIILETPDITNDESIYKYEIQNLYKLYFEK
What is the function of this protein?
Plays a role in mitochondrial DNA base excision repair (BER) pathway induced by oxidative stress (PubMed:31386260).  Has apurinic/apyrimidinic (AP) endonuclease activity towards double-stranded DNA (dsDNA) with a preference for C as opposite base (PubMed:31386260).  Has 3'-phosphatase activity; removes 3'-phosphate from blunt-end, recessed, and gapped DNA templates and thus, removes 3'-blocks for DNA polymerase activity during BER (PubMed:31386260).  Lacks 3'-5' exonuclease activity and does not cleave damaged bases by nucleotide incision repair (NIR) (PubMed:31386260).
What are the official names of this protein?
Apurinic-apyrimidinic endonuclease 1, PfApn1.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: SLAA_DEIAC
Sequence: MGRFIFVSFGLLVVYLSLSGTAADCSSSWSSYEGHCYKAFKQSKTWADAESFCTKQVNGGHLVSIESSGEADFVAHLIAQKIKSAKIHVWIGLRAQNKEKQCSIEWSDGSSISYENWIEEESKKCLGVHKATGFRKWENFYCEQRDPFVCEA
What is the function of this protein?
Anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factors IX and factor X in the presence of calcium with a 1 to 1 stoichiometry.  Also inhibits platelet aggregation by binding to platelet glycoprotein Ibalpha (GP1BA) and functioning as a blocker of vWF.  Is devoid of hemorrhagic and lethal activities.  Possesses antithrombotic and thrombolytic activities.  Also hydrolyzes the Aalpha-chain of fibrinogen.  Does not affect the Bbeta-chain and the gamma chain (By similarity).
What are the official names of this protein?
Snaclec anticoagulant protein subunit A, AaACP-A.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYL_BARQU
Sequence: MTIEHSNVGERYNPRAREQKWQAIWDEKKIFQITEENCREKYYVLEMFPYPSGRIHMGHVRNYTMGDVVARYKRAKGFDVLHPMGWDAFGMPAENAALQSKVHPKTWTYQNIAVMRGQLKQLGLSLDWSREFATCDVAYYHRQQMLFLDLYQKGLVARKVAKVNWDPVDQTVLANEQVVDGCGWRSGALVEQRELAQWFFKISDFSEDLLAGLEELEQWPEKVRTMQKNWIGKSQGLLIRWALKSTNGADEVCEAFNEVVCYSTRPDTLFGASFLALSVDHPISQALAQKDKALSAFIENCRCGGMTTAALETAEKQGFCTSLLAVHPFNPRIHLPVYIANFVLMDYGTGAVFGCPAHDQRDWDFAHKYDLPVQPVVLPKGSDAEDFVIAETPYTGDGVMINSDFLDGLTPQEAFEAAAERLEGQMLNGQPQGKRTVQFRLRDWGISRQRYWGCPIPIIHCAACGVVPVPRADLPVELPDDVTFDQPGNPLERHEKWQKVACPVCGQSAKRETDTMDTFVDSSWYYARFTAPWAQEPVDKNAIAEWLPVQQYIGGIEHAILHLLYARFFMRAMKLIGYVTVDEPFKGLFTQGMVVHETYRDDQGWVSPAEISIIEKDGKRQAHKLTDQSEVTIGLIEKMSKSKKNVVDPDDIIASYGADTVRWFVLSDSPPERDVIWTESGVEGAYRFVQRVWRCVVLSAPVLKEVIPCTGHQGAALELSKAAHRMLCTVEDDLEKFAFNRAIARLYEFLNIMAPLLNKIASVEDEMKASLRQAMDFFLALIAPIMPHLAEECHAALGGKTLICELPWPVYDPALIVEDCCTLPVQINGKKRGEVTVAATASEAMIEEAVLALDFVQAHLVEKSIKKMIIVPQRIVNVVL
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OGA_MOUSE
Sequence: MVQKESQAALEERESERNANPAAASGASLEQSVAPAPGEDNPSGAGAAAVVGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSVLTKEEEKKQPDEEPMDMVVEKQEEAEHKNDNQILTEIVEAKMAEELRPMDTDKESMAESKSPEMSMQEDCIPDVAPMQTDEQTQKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGFPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL
What is the function of this protein?
Cleaves GlcNAc but not GalNAc from O-glycosylated proteins.  Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:16517082).  Does not bind acetyl-CoA and does not have histone acetyltransferase activity.
What are the official names of this protein?
Protein O-GlcNAcase, OGA, Beta-N-acetylhexosaminidase, Beta-hexosaminidase, Bifunctional protein NCOAT, Meningioma-expressed antigen 5, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 84 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LEUC_BUCUE
Sequence: MSKTLYQKIYDSHVVYKDKSNMSILYIDLHLIHEVTSPQAFDSLRHKKRGVRQPQKTFATMDHNVSTQSKNINASGSMAQKQMEQLIKNCNEFNISLYDVNNPNQGIVHVIAPEKGMTLPGMTIVCGDSHTSTHGAFGALSFGIGTSEVEHVLATQTLKQKRFKNMKITIIGKVPEFITAKDIILFIIGQLGSSRGTGYVIEFFGDVINNMSMEERMTLCNMAIEMGAKSGLIAPDEITYSYLKNKIYSPYGIFWKKAIDYWSTLKSDKNAYFDKFFTIDISNLAPQITWGTNPDQVISIDEKIPNHNKFDSSIIRDSIKSACKYMGLKEGTYLTDVSVDKVFIGSCTNARIEDLRSASKILKNKKISKNVKAIVVPGSGSVKEQAEKEGLDKIFINAGFEWRLPGCSMCLGMNNDRLNFGERCASXSNRNFEGRQGRGGRTH
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: I2B1_CONLT
Sequence: MMFRLTSVLLVIVLLNLVVLTNACHMDCSKMICCSGICCFYCGLPSCDDTRRALLQRLLGHQR
What are the official names of this protein?
Conotoxin Lt11.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUC_CAMJR
Sequence: MAKTLYEKVFDAHVVYEGKNELPILYIDRHLIHEVTSPQAFSGLKMAKRRMARADLTLATIDHDVSTKSVDLNACSDMAKEQITTLMQNTKEFGVRLLGLGDKNQGIVHIVGPELGFTLPGVTLVCGDSHTATHGAFGALAFGIGTSEVEHVMATQTLKQAKLKTMKIECKGQFQKGVYTKDLILYLIAQYGTAKGTGYAIEFCGELIRNLSMEARMTLCNMAIEFGAKVGMIAPDEITFEYIKGKEFAPKGEEFQKYCEYWKSLRSDEGAKYDASITLDVSKIKPQISYGTNPSQVIGIDEKIPKISDFKNQSEQKSLLDALYYVNLEQDQVIEGVKIDIVFIGSCTNGRLEDLKIAADILKGRKIHKNVKALIVPGSMQVRKEAENLGLDKIFIEAGCEWRYAGCSMCLGMNDDKANSGQRVASTSNRNFVGRQGKGSITHLMSPASAAACAIEGVICDNRKYLGV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: AMPA_RHOOB
Sequence: MSTRTARPLGPQLALAGTVGKRVDVLVIGLTSSSDGPEIALGDGIVDEAVLTGLLDTLVAVGASGKAEETTRIPAPDTLPVDSVLAVGLGSAEKLDAEQIRKSAGAAARTLSGVGTAATTLSVLDLGAAAEGFALGAYRFTEFKSAKSAPGPDAQPVARVELLVSSPRAKESKDTLARSAAIAEAVATAREFVNTPPSHLFPAEFADRAKELGTDSGLKVEVLDEKALEKNGYGGILGVGKGSSRLPRLVRLSYSAKKRNAPKVALVGKGITFDTGGISIKPAAGMENMTSDMGGAAAVVATVVLAAKLGLPVDVTATVPMAENMPSSTAQRPGDVLTQYGGTTVEVINTDAEGRLVLADAIVRACEDDPDYLIDTATLTGAQMVALGNRTPGVMGTDAFRDRVAAISQEIGENAWAMPMPAELRSDLDSKIADLANVTNHRWGGMLAAALYLKEFVADGVQWAHIDVAGPAYNSSGPWGYTGRGGTGVPVRTMISVIEDIAAHG
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.