PharMolix/UniProtQA huggingface dataset:
Protein: IF2_POLSJ
Sequence: MSSTTTVAEFAAELNKPTATLIEQLTSAGVAKVQASDHLSEVDKQKLLGYLQASHGTVTAERKKITLVKKSTTEIKQADATGKARTIQVEVRKKRTFVKREDGSDLPAEEVQPEVVAAPQVPVIDDAELIRREEEASRHAELLRRQEAELAEKRRLREELDAKEAARELERQAAAESAKAAAEAAEAAKKAKPVTGKAKEVAQPAGAEASRAAAETAVAEEAAATKAADAAVVQAAAKAKATAEFQADAAKAQDLQERRRKAEAEAAGIRAMMSAPKRVLVPHVDPKAAIKGTLHKPAVAPGAAKPAAAAGAPGAPGAAGKKEVKSENLSSTWKDDAAKKKGIPSRGATAVPGRGNFRSGPRGRRSNDRDARPESTFVAPTEFKVIEVHVPETITVAELAHKMSVKSSEVIKHLMKLGQMVTINQPLDQDTAMIVVEEMGHKAITAALDDPEAFTDDDVQGQQAEALPRAPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETPRGMISFLDTPGHEAFTAMRARGAQATDIVILVVAADDGVMPQTKEAIKHAKAAGVPIVVAINKIDKADANMDRVKGELVTEEVIPEEFGGESPFVGVSARTGEGVDTLLEQVLLQAEVLELRAPVEALAKGLVIEAQLDKGRGPVATVLIQSGTLKTGDVVLAGSTYGRVRAMLDENGKPIKTAGPSIPVEIQGLTEVPQAGDEFMVMTDERRAREIATYRAGKFRNTKLAKQQASKLENMFSDISAGEVKMLPIIIKADVQGSQEALAQSLLKLSTDEVKVQLVYSGVGGISESDVNLAIASKAVLIGFNTRADAQARKQAENNGIDIRYYNIIYDAVDELKAAMSGMLTPDKKEEVIGTAEIRQVFKVSKIGSIAGCMVTAGIVRRTARLRLLRDNVVIFTGELDSLKRFKDDVKEVKESFECGLNIKNYNDIQEGDILEFFEIKEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAK1_MOUSE
Sequence: MAAAYLDPNLNHTPSSSTKTHLGTGMERSPGAMERVLKVFHYFESSSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMQEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGIPAMAGSIYQGQASLLDQTELWNHRPQEMSMWQPSVEDSAALDLRGMGQVLPPHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSFQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLSNLSSISSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPALPASTHREIEMAQKLLNSDLGELISKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
What is the function of this protein?
Does not contain a kinase domain and inhibits PTK2/FAK1 phosphorylation and signaling.  Its enhanced expression can attenuate the nuclear accumulation of LPXN and limit its ability to enhance serum response factor (SRF)-dependent gene transcription (By similarity).
What are the official names of this protein?
Focal adhesion kinase 1, FADK 1, Focal adhesion kinase-related nonkinase, FRNK, Protein-tyrosine kinase 2, p125FAK, pp125FAK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, cilium basal body. Note=Constituent of focal adhesions. Detected at microtubules.
Protein: ODO1_HAEIN
Sequence: MQQNKAFDDWLASTALGGANQSYIEELYESYLSDPQSVEESWRKTFDSLPKTTALEQPHTPVRDYFRRLARENHNEAVTVIDPAAGAKLVKVLQFINAYRFRGHLEANLDPLNYYRWKVSFVPELDYRHHGFTEQDLNETFNINHYVYKRDTIKLGELAQMLKETYCGSIGLEFMHVQDMEQKMWLQSKMESLLDKPLFTSEERVNFLRELTAADGLERYLGAKFPGAKRFSLEGSDAFIPLMKEIIRHSSRQGVNDVVMGMAHRGRLNMLVNVLGKKPENLFDEFAGKHSSERTGDVKYHQGFSSDFAVDDKRVHLTLAFNPSHLEIVSPVVIGSVRSRQTRMNDTEHSKVLAITVHGDSAVAGQGVVQETLNMSNTRGYSVGGTIRIVINNQIGFTTSNPNDTRSTEYCTDIAKMIQAPIIHVNGDDPEAVAFAARMAVEYRNLFKRDIFIDLISYRRHGHNEADEPLATQPMMYSIIKKHPTPRKVYADRLVSEGVMTEEQVTEMANDYRDALDNGDRVVSEWREMDTAKMDWLQYLNYDWTAPYESKFSQERFLTLAKRVCEYPESLRAHPRVEKIYNDRKAMYQGEKLLDWGMAETMAYATLLDEGVNVRLSGEDAGRGTFFHRHAVVHNQNDGTGYVPLTHLHANQGRFEVWDSVLSEESVLAFEYGYATTDPKTLTIWEAQFGDFANGAQIVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQSLRKMRRPLIAISPKSLLRHPLAVSSLDELINGTFQTVIGEIDELDPKDVKRVVMCSGKVYYDLLEQRRANNQKDVAIIRIEQLYPFPHEDVKKALEPYAHVTDYVWCQEEPLNQGAWYCSKHNFESAIPESVKLKYAGRPASASPAVGYMSLHTKQQKQLVEDALSF
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: GLPO_STRP6
Sequence: MEFSKETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLDTGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDPMLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGLLGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDKRQIIGVKARDLLTDQEIIIKAKLVINTTGPWSDEIRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYVDTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLQHPQVTQEDVDYLLGIVNNRFPNANLTINDIESSWAGLRPLLSGNSASDYNGGNSGKLSDDSFDHLIDTVKAYINHEDSREAVEKAIKQVETSTSEKELDPSAVSRGSSFERDENGLFTLAGGKITDYRKMAEGALKVIIQVLKEDFGKSFKLINSTTYPVSGGEINPANVDSELEAYAQLGTLSGLSMDDARYLANLYGSNAPKVFALTRQLKAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLDALIVPVIEEMAKHFDWSTDEKVKQEEELRRVIAENDLSALKGQQED
What are the official names of this protein?
Alpha-glycerophosphate oxidase, Glycerol-3-phosphate oxidase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_STRMK
Sequence: MARPDLTARLHAQRALRDAQGRRRPRRTVTRRDGVRLEVDGQWLTGFCSNDYLGLAQQFSVVNALQDAAAREGAGAGASHLVCGHHALHEALEREVAEWLGYPRALLFGSGFAANLAVQQALLSEENDVCVQDKLNHASLLDATRLAGARLRRYPHLDAEGAMRQLKHAPDGAAMLATDGVFSMDGDIAPLRALSLVARLQQALFYVDDAHGVGVVGDGRGAVAAAGLGVDDVPLQLVTLGKALGGSGALVLGRDDLIEHLAETARPYIYTTAVPPAMAAAALEAVRLARRDNWRRSKLTDLIALFRSEARRHGLDLMASDTPIQPLLCGDDHTAVAMSTALEQAGWLVGAIRPPTVPEGKARLRVTLSALHTPEQVRGLVEAIASARERVALAVREAAPPPLPVFA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: DBHC_NEIMA
Sequence: MNKSELIQAIADEAELSKRAAAEFVNAFVSVVTQELKDGNDVTLVGFGTFHAAQSAERQGRNPKTGEPLTIAARKTPKFRSGKALKDAVNG
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU-beta 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PSLS_METJA
Sequence: MKAFEFLYEDFQRGLTVVLDKGLPPKFVEDYLKVCGDYIDFVKFGWGTSAVIDRDVVKEKINYYKDWGIKVYPGGTLFEYAYSKGKFDEFLNECEKLGFEAVEISDGSSDISLEERKNAIKRAKDNGFMVLTEVGKKMPDKDKQLTIDDRIKLINFDLDAGADYVIIEGRESGKGIGLFDKEGKVKENELDVLAKNVDINKVIFEAPQKSQQVAFILKFGSSVNLANIAFDEVISLETLRRGLRGDTFGKV
What is the function of this protein?
Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL).
What are the official names of this protein?
Phosphosulfolactate synthase, (2R)-phospho-3-sulfolactate synthase, PSL synthase.
What is the protein family that this protein belongs to?
Belongs to the phosphosulfolactate synthase family.
Protein: FABZ_CERS1
Sequence: MTEAAEATLSADIQLIQRIIPHRYPFLLVDRVRDIVPNKSAVGIKCVTMNEPQFTGHFPGLPIFPGVQIIEAMAQTSAVLVGVSMDLADKGAKVYFMGIDGAKFRRKVVPGDVLEMTVTVKRGGGKVWKFEGRASVDGELAAEAEFSAMLDLPKG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_SHEPA
Sequence: MESQRNILLIGLLFVSFLLWQQWQADKAPQPVAAAQTQSSIPASTVADAHSSDVPDADSAVPEATPASKELITVITDQLEIKIDPVGGDIVYSALLSHKLEEKGDDPFVLLEQTNDIYYIAQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQETLNVPLTYVSDKGVAYTKVFVFTRGKYNIAVDYKINNTSDAQLQVQMYGQIKHSIKKSESSMMMPTYRGGAFSTADTRYEKYSFDDMADKNLDKSTLGGWVAMLQHYFVSAWVPPANDKNIIFSSVSAGGLANIGFRGALYDIAPGTEQSIKAEFYVGPKDQEALSALSPSLNLVVDYGFLWWLAVPIYKLLMFFQSIVGNWGIAIILITLTVRGMLYPLTKAQYTSMAKMRNLQPKLAELKERFGDDRQKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVMPILMGISMFVMQKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLEKKGLK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RF3_STAAT
Sequence: MNLKQEVESRKTFAIISHPDAGKTTLTEKLLYFSGAIREAGTVKGKKTGKFATSDWMKVEQERGISVTSSVMQFDYDDYKINILDTPGHEDFSEDTYRTLMAVDSAVMVIDCAKGIEPQTLKLFKVCKMRGIPIFTFINKLDRVGKEPFELLDEIEETLNIETYPMNWPIGMGQSFFGIIDRKSKTIEPFRDEENILHLNDDFELEEDHAITNDSDFEQAIEELMLVEEAGEAFDNDALLSGDLTPVFFGSALANFGVQNFLNAYVDFAPMPNARQTKEDVEVSPFDDSFSGFIFKIQANMDPKHRDRIAFMRVVSGAFERGMDVTLQRTNKKQKITRSTSFMADDKETVNHAVAGDIIGLYDTGNYQIGDTLVGGKQTYSFQDLPQFTPEIFMKVSAKNVMKQKHFHKGIEQLVQEGAIQYYKTLHTNQIILGAVGQLQFEVFEHRMKNEYNVDVVMEPVGRKIARWIENEDQITDKMNTSRSILVKDRYDDLVFLFENEFATRWFEEKFPEIKLYSLL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_MYCBP
Sequence: MATLADPRDIILAPVISEKSYGLLDDNVYTFLVRPDSNKTQIKIAVEKIFAVKVASVNTANRQGKRKRTRTGYGKRKSTKRAIVTLAPGSRPIDLFGAPA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: ELBA3_DROME
Sequence: MSNISNDSGLDDSANSGAVVSANGPLAATRLSWFLAEVDDGLMKDGKPNGRRRLCVLHSMELLESDVSDKYMTRFVEFRVNGMVLEAKLILAADERRLVDAALLSMSKEEREDAGGQQLLVQYTENEKAGERLIQKLVSPNNVMLLSTKPELKGNPLVRLAPGCIAHILYAYESRDYMEKILLHLKARSFDLAFDDNLEAEPEAMNDDTWMLVQYSPEPEMVVYQVVQYRQTVWRKENLFKDVIAYMQLPGSDIVLQAVVISYGQDKEVQDAKYEELQRFSFDIDFPLPEELEKHPDHMTSTALFSRTSLYQKAEQRDTTGEHRELRKSLEQMSEKAQGEAQMIIDAFDMVDNINKNLQSRLSGEVRSVVEVTSGDELH
What is the function of this protein?
The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis.  It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity.  Elba3 lacks DNA-binding activity and plays the role of an adapter protein, bringing Elba1 and 2 together, thereby establishing a complex that recognizes the asymmetric sequence motif through the BEN domains of Elba1 and 2 (PubMed:23240086).
What are the official names of this protein?
Early boundary activity protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: BIOB_NOVAD
Sequence: MQETALLERESAGTGNAPVRTDWTREEIAALFDLPFTELLFRAAEVHRAHHRAGEVQLCTLLSIKTGGCPEDCGYCSQSVKADSGVEATKLMEVQKVLQSAAQAKDNGSKRFCMGAAWRNPKDRDMPAIISMIKGVREMGMETCMTLGMLTPSQAAQLADAGLDYYNHNIDTSPERYEEVITTRTFADRLQTLDNVRNAGINVCSGGIVGMGETRADRVGFVHALATLEQHPESVPVNALVPIKGTVLGDMLADTPLAKIDDIEFVRTVAVARITMPLSMVRLSAGRESMSEATQALCFMAGANSIFTGDKLLTAANAGDDADAAMFKRLGLKPMEGEEPMRAMKSVGGCSGGCAA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: BEATH_CLABR
Sequence: MNVTMHSKKLLKPSIPTPNHLQKLNLSLLDQIQIPFYVGLIFHYETLSDNSDITLSKLESSLSETLTLYYHVAGRYNGTDCVIECNDQGIGYVETAFDVELHQFLLGEESNNLDLLVGLSGFLSETETPPLAAIQLNMFKCGGLVIGAQFNHIIGDMFTMSTFMNSWAKACRVGIKEVAHPTFGLAPLMPSAKVLNIPPPPSFEGVKFVSKRFVFNENAITRLRKEATEEDGDGDDDQKKKRPSRVDLVTAFLSKSLIEMDCAKKEQTKSRPSLMVHMMNLRKRTKLALENDVSGNFFIVVNAESKITVAPKITDLTESLGSACGEIISEVAKVDDAEVVSSMVLNSVREFYYEWGKGEKNVFLYTSWCRFPLYEVDFGWGIPSLVDTTAVPFGLIVLMDEAPAGDGIAVRACLSEHDMIQFQQHHQLLSYVS
What is the function of this protein?
Involved in the biosynthesis of benzyl acetate, a major constituent of the floral scent.  Can use benzylalcohol, cinnamylalcohol, 3-cis-hexene-1-ol or heptanol as substrates.  Has some activity with 2-phenylethanol and 2-naphtalene-ethanol, but no activity with linalool, 2-hydroxybenzylalcohol, 3-hydroxybenzylalcohol or 4-hydroxybenzylalcohol.
What are the official names of this protein?
Acetyl-CoA-benzylalcohol acetyltransferase, CbBEAT-1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: CM3A_CONST
Sequence: MMSKLGVLLTVCPLLFPLTALPPDGDQPADRPAERMQDDISSDEHPLFDKRQNCCNGGCSSKWCRDHARCCGR
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav).  This toxin moderately blocks rNav1. 1/SCN1A, rNav1. 2/SCN2A, rNav1. 3/SCN3A, rNav1. 4/SCN4A, and mNav1. 6/SCN8A.
What are the official names of this protein?
Mu-conotoxin SIIIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PANE_PYRAB
Sequence: MKIYILGAGAIGSLFGGLLANAGEDVLLIGRDPHVSAINEKGLKIVGIKDLNVKVEATTRVPEEKPDLIVLATKSYSTIEALKSARHIVKGSWVLSIQNGIGNEDKIIEFGGKAIGGITTNGAMVEAPGVIKWTGKGVTIIGLYPQGKEKFIEKVADVFNSADIETHVSENIISWIWAKAIVNSAINPIGTLLEVKNKVIRENDFLLSMAMEVVKEGCRVALQNGIEFDVPPMDLFFQTLEQTRENYNSMLQDIWRGKKTEVDYINGKIVEYAKAVNLEAPMNLLLWGLIKGKEALEGKK
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_YERPG
Sequence: MATINQLVRKPRSMKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQSRSKYGVKKPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: VPS27_SCHPO
Sequence: MSRWWNSNSQFASDIEKATSETLPAGSEEISLYLEISDQIRSKSVDPKFAMRILKSRIDHSNPNVQIMALKLTDTCVKNGGSGFLLEIASREFMDNLVSILRSPAGIDEDVKMVILRYIQSWALAVPDTNSPLSYIIHVYQNLKDGDYEFPEPSQNITSKFLDTETPPDWTDSEVCLRCRTPFTFTNRKHHCRNCGGVFCNQCSSKTLSLPHLGINQPVRVCDSCYSLRTKPKGSKSRARNERKFHAKTRKTPSKPVTNNEDEDIKRAIELSLKEMPQSREPPSYERPSEANVVISQDQHLTEDEDEELKRAIAISLEEAQKSSQKDDNVTAPNNMNISYPSVPAHTVSTDIRSSPFSGRPSDNPSTLISTADADNITLYATLVQKLKKLPPGSIFTEYQLQELHENMGVMRTRMMRSLGETMSKYNGLIQALQKLQTCMRLNDALIEQRLSSTYAHHYIDSSMDSNRSIEPEPDVISTVRNSSTIPQASSSSVPKIVVDSSPVTENPPSHSDVMGQKDTISSYYSTDTDVSANVMGNRHDEVVFSDTASGEKNTKLNIDESTNYYNTDSIDKVGEPFDEISSGYDDLMNGNDKQGNDIPEVQEASLIEL
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 27, Suppressor of ste12 deletion protein 4.
What is the protein family that this protein belongs to?
Belongs to the VPS27 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: MURB_RHIWR
Sequence: MSPAASSATRPSTLPPVRGRLTAGAPLAPLVWFKSGGAAEWLFEPADVDDLSDFLAALDPAVPVMGLGLGSNLIVRDGGVPGVVVRLGKPFARVERLDATTLRCGGGASGILVSSTARDAGIGGVEFLRSIPGTVGGFVRMNGGAYGREVKDVLVEGEVVLRSGERRVLSLAELGYTYRHSALPEGAIVVAATFRGHAEAPAVVQAEMDRIAAEREASQPLRSRTGGSTFKNPQGHKAWQLVDAAGCRGLTRGDAQVSEKHCNFLLNLGTASSADIEGLGEEVRERVKANSGVTLEWEIQRVGVNP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFH1_METMP
Sequence: MDLMSFKEKELSKKDCVELFEDTENFFDILKLADSLRKDIVGDTVTYVVNANINFTNVCSGTCKFCAFKAEHGDPNAFFLSPEQVAKKALEARKTGATEVCIQGGLLKEIDTYFQAEILKKVKEITKTYGGIDVHAFSPMEVKSAAENAGLSVKEALKILKENGLNSMPGTAAEILDDEVRSEICPTKLKTSEWIDVVSTAHKTGINTTCTMMYGHIEENKHLAEHLSILRKIQKETGGFTEFVPLTFLHENAPLHHMDRVKSGASGMLDLKVYAISRIFFKDYIKNIQTSWVKLGTKLSQISLNCGANDIGGTLMEESISKAAGGSYGTYMSEEKLKDMVLAVGRIPKQRNTCYEIIE
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase 1, FO synthase subunit 2 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: 4CLL8_ARATH
Sequence: MANSQRSSSLIDPRNGFCTSNSTFYSKRKPLALPSKESLDITTFISSQTYRGKTAFIDAATDHRISFSDLWMAVDRVADCLLHDVGIRRGDVVLVLSPNTISIPIVCLSVMSLGAVLTTANPLNTASEILRQIADSNPKLAFTTPELAPKIASSGISIVLERVEDTLRVPRGLKVVGNLTEMMKKEPSGQAVRNQVHKDDTAMLLYSSGTTGRSKGVNSSHGNLIAHVARYIAEPFEQPQQTFICTVPLFHTFGLLNFVLATLALGTTVVILPRFDLGEMMAAVEKYRATTLILVPPVLVTMINKADQIMKKYDVSFLRTVRCGGAPLSKEVTQGFMKKYPTVDVYQGYALTESNGAGASIESVEESRRYGAVGLLSCGVEARIVDPNTGQVMGLNQTGELWLKGPSIAKGYFRNEEEIITSEGWLKTGDLCYIDNDGFLFIVDRLKELIKYKGYQVPPAELEALLLNHPDILDAAVIPFPDKEAGQFPMAYVARKPESNLCEKKVIDFISKQVAPYKKIRKVAFIDSIPKTPSGKTLRKDLIKFAISKI
What is the function of this protein?
Carboxylate--CoA ligase that may use 4-coumarate as substrate.  Follows a two-step reaction mechanism, wherein the carboxylate substrate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield the final CoA thioester.
What are the official names of this protein?
4-coumarate--CoA ligase-like 8, 4-coumarate--CoA ligase isoform 11, At4CL11.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PRDX1_CRIGR
Sequence: MSSGNAKIGYPAPNFKATAVMPDGQFRDICLSEYRGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITINDLPVGRSVDEILRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.  Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity).  Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).
What are the official names of this protein?
Peroxiredoxin-1, Thioredoxin peroxidase 2, TPX-2, Thioredoxin-dependent peroxiredoxin 1.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALA4_ARATH
Sequence: MARGRIRSKLRLSHIYTFGCLRPSADEGQDPHPIQGPGFSRTVYCNQPHMHKKKPLKYRSNYVSTTRYNLITFFPKCLYEQFHRAANFYFLVAAILSVFPLSPFNKWSMIAPLVFVVGLSMLKEALEDWSRFMQDVKINASKVYVHKSDGEFRRRKWKKISVGDIVKVEKDGFFPADLLLLSSSYEDGICYVETMNLDGETNLKVKRSLEVTLSLDDYDSFKDFTGIIRCEDPNPSLYTFVGNLEYERQIFPLDPSQILLRDSKLRNTPYVYGVVVFTGHDTKVMQNSTKSPSKRSRIEKTMDYIIYTLLVLLILISCISSSGFAWETKFHMPKWWYLRPEEPENLTNPSNPVYAGFVHLITALLLYGYLIPISLYVSIEVVKVLQASFINKDLHMYDSESGVPAHARTSNLNEELGQVDTILSDKTGTLTCNQMDFLKCSIAGTSYGVRSSEVEVAAAQQMAVDLDEHGEVSSRTSTPRAQARDIEVESSITPRIPIKGFGFEDIRLMDGNWLREPHTDDILLFFRILAICHTAIPELNEETGKYTYEAESPDEASFLTAASEFGFVFFKRTQSSVYVHERLSHSGQTIEREYKVLNLLDFTSKRKRMSVVVRDEEGQILLLCKGADSIIFERLAKNGKVYLGPTTKHLNEYGEAGLRTLALSYRKLDEEEYSAWNAEFHKAKTSIGSDRDELLERISDMIEKDLILVGATAVEDKLQKGVPQCIDKLAQAGLKLWVLTGDKMETAINIGYSCSLLRQGMKQICITVVNSEGASQDAKAVKDNILNQITKAVQMVKLEKDPHAAFALIIDGKTLTYALEDEMKYQFLALAVDCASVICCRVSPKQKALVTRLVKEGTGKITLAIGDGANDVGMIQEADIGVGISGVEGMQAVMASDFSIAQFRFLERLLVVHGHWCYKRIAQMICYFFYKNIAFGLTLFYFEAFTGFSGQSVYNDYYLLLFNVVLTSLPVIALGVFEQDVSSEICLQFPALYQQGKKNLFFDWYRILGWMGNGVYSSLVIFFLNIGIIYEQAFRVSGQTADMDAVGTTMFTCIIWAVNVQIALTVSHFTWIQHVLIWGSIGLWYLFVALYGMMPPSLSGNIYRILVEILAPAPIYWIATFLVTVTTVLPYFAHISFQRFLHPLDHHIIQEIKYYKRDVEDRRMWTRERTKAREKTKIGFTARVDAKIRHLRSKLNKKQSNMSQFSTQDTMSPRSV
What is the function of this protein?
Involved in transport of phospholipids.
What are the official names of this protein?
Probable phospholipid-transporting ATPase 4, AtALA4, Aminophospholipid flippase 4.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.