PharMolix/UniProtQA huggingface dataset:
Protein: NUD10_MOUSE
Sequence: MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPDGAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVFVLTVTELLEDWEDSVSIGRKREWFKIEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSAAPSPPESEP
What is the function of this protein?
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction.  Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates.  The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A.  Also able to hydrolyze 5-phosphoribose 1-diphosphate; however, the relevance of such activity in vivo remains unclear.
What are the official names of this protein?
Diphosphoinositol polyphosphate phosphohydrolase 3-alpha, DIPP-3-alpha, DIPP3-alpha, Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha, Diadenosine hexaphosphate hydrolase (AMP-forming), Nucleoside diphosphate-linked moiety X motif 10, Nudix motif 10.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. DIPP subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPC8_HUMAN
Sequence: MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKKEAPYTLVGSISEPGLGLLSWWTSN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.  Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses.  Acts as nuclear and cytosolic DNA sensor involved in innate immune response.  Can sense non-self dsDNA that serves as template for transcription into dsRNA.  The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC8, RNA polymerase III subunit C8, DNA-directed RNA polymerase III subunit H, RNA polymerase III subunit 22.9 kDa subunit, RPC22.9.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AGLB3_ARCFU
Sequence: MQNAESWFKKYWHLSVLVIAALISVKLRILNPWNSVFTWTVRLGGNDPWYYYRLIENTIHNFPHRIWFDPFTYYPYGSYTHFGPFLVYLGSIAGIIFSATSGESLRAVLAFIPAIGGVLAILPVYLLTREVFDKRAAVIAAFLIAIVPGQFLQRSILGFNDHHIWEAFWQVSALGTFLLAYNRWKGHDLSHNLTARQMAYPVIAGITIGLYVLSWGAGFIIAPIILAFMFFAFVLAGFVNADRKNLSLVAVVTFAVSALIYLPFAFNYPGFSTIFYSPFQLLVLLGSAVIAAAFYQIEKWNDVGFFERVGLGRKGMPLAVIVLTALIMGLFFVISPDFARNLLSVVRVVQPKGGALTIAEVYPFFFTHNGEFTLTNAVLHFGALFFFGMAGILYSAYRFLKRRSFPEMALLIWAIAMFIALWGQNRFAYYFAAVSAVYSALALSVVFDKLHLYRALENAIGARNKLSYFRVAFALLIALAAIYPTYILADAQSSYAGGPNKQWYDALTWMRENTPDGEKYDEYYLQLYPTPQSNKEPFSYPFETYGVISWWDYGHWIEAVAHRMPIANPFQAGIGNKYNNVPGASSFFTAENESYAEFVAEKLNVKYVVSDIEMETGKYYAMAVWAEGDLPLAEKYYGGYFYYSPTGTFGYANSQWDIPLNSIIIPLRIPSELYYSTMEAKLHLFDGSGLSHYRMIYESDYPAEWKSYSSQVNLNNESQVLQTALYEAVMRARYGVSPTMGTQEVLYKYAYTQLYEKKMGIPVKIAPSGYVKIFERVKGAVVTGKVSANVTEVSVNATIKTNQNRTFEYWQTVEVKNGTYTVVLPYSHNSDYPVKPITPYHIKAGNVVKEITIYESQVQNGEIIQLDL
What is the function of this protein?
Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (a glucose-linked heptasaccharide composed of 3 Glc, 2 Man, 2 Gal and a sulfate for A. fulgidus AglB-L) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.
What are the official names of this protein?
Dolichyl-phosphooligosaccharide-protein glycotransferase 3, Archaeal glycosylation protein B, AglB-L, AglB-Long, Oligosaccharyl transferase, OST, OTase.
What is the protein family that this protein belongs to?
Belongs to the STT3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPE_ECOUT
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CH10_RUMCH
Sequence: MKIKPLGDRVVIKMLESEETTKSGIVLPGSAKEKPQVAEIVAVGPGTVVDGKEVKMEVKVGDRVLTSKYSGTEVKFDGQEYTILKQGDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_AADNV
Sequence: MADSTTMEHDGRGTKRKREADGGSGQGVGKGNSNAVKEGYGPNITEMVPRNIFNKGNHTIYHVVKTQKYLDFNYVTNQNPYIIPYQTAGFWGSMWDQTDIGNNQSINIMKALNAVALGVTWIKGEITFEVYSVTRQRLLTGTTNQTTWDFETSQNMFIADADREPENFNLETVAATGPLAQQTTQTLLFNSHNDRYTKYELPQRNQYTREINFQQLTNNYMWRPLDISKETNFRSLIPMSEGVYTKSENLRQTEFTYETTTYATSGATTRQTLFRNRTSYPRMHIAQPQVPDETGFMKFRYQVRMSTKLHLNFHMYPDYATNNNLEYMHRQTILLPQVAETNGIVACMPYEINTQ
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of size variants of the capsid proteins, which differ in the N-terminushe capsid encapsulates the genomic ssDNA.  Capsid proteins are responsible for the attachment to host cell receptors.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (By similarity).
What are the official names of this protein?
Capsid protein VP1/VP2, Coat protein VP1/VP2.
What is the protein family that this protein belongs to?
Belongs to the parvoviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RDGC_BURO0
Sequence: MWFKNLQLHRLPAPWAVTPDQMEKWLAPHAFQPGSSVEMQRVGWASPRDDGALVYSNNRQMLLLFRAEKKLLPASVVNQVTKARALEVEEQQGFKVGRKQLRELKEQVTDELLPRAFSIRRDTRVWIDTANGWLVIDAAAQALADDVRSLLVKSIDQLPLAGVHVARSPVAAMTDWLLSGEAPGGFTVDQDAELRSSGEGGATVRYVGHALEANDMRRHIEAGKQCMRLAMTWNDRISFVLTPSLTIKRVTPLDVIKEAADPTAQNDDERFDSDFTLMTGELARMLASLVDILGGDQQDAIQQAAAA
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
Protein: RL8_TOBAC
Sequence: MGRLIRAQRKGAGSVFKSHTHHRKGPARFRSLDFGERNGYLKGVITEVIHDPGRGAPLARVTFRYPFRYNHQKELFVAAEGMYTGQFVYCGKKATLMVGNVLPLRSIPEGAVVCNVEHKVGDRGVFARCSGAYAIVISHNPDNGTTRIKLPSGSKKIVPSGCRRMIGQVAGGGRTEKPMLKAGNAYHKYRVKRNCWPKVRGVAMNPVEHPHGGGNHQHIGHASTVARDAPPGQKVGLIAGRRTGRLRGQAAATAAKADKA
What are the official names of this protein?
60S ribosomal protein L8, 60S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_BUCAI
Sequence: MLIFFNKYLHINLNILSYIPYRAIFSLLTSFFINLYIGPYFIYYFKKLQTYQIIRNNGPKTHYSKKNTPTMGGIFIIFSILFSTILYCNLSNIYIWYVISILIGYGLIGFIDDYKKIKYKNSQGLKLKWKYFFLSIIAFIFICMIKINNKDIISTELIIPFCIKNDFEINYLYIFLSYFVLVGTSNAVNLTDGLDGLAIMPVIFLTCGLTLISLFSDNINISHYLHVQYVKNSTELAILCMAIVGSGLGFLWFNSYPAKVFMGDVGSLALGGSLGAIAILLHQELLLIIMGGIFVFETISVILQIISFKIRKKRIFQMAPVHHHYEVKGILEPLIIVRFWIVSLILLLISLISLKVC
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSGA_ECOL6
Sequence: MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIVISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHERTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLNKIDLLDDEGMEFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLWHLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILESMAQVKTRKNFSDTDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAH_BUCA5
Sequence: MSTYFISDIHGCYEEFRILLEKSSFNDKKDYLWIAGDLVSRGPDSLKVVKYLYSLKDRVQIVLGNHDINLIAVHAGIKDNKKENYFDEFLSSPDSVELINWLRCQSFLKVDEKRKIIMSHAGISPQWDINIAKVCALEIEDRLSHKNYALFLKEIYHNNIDFWRLDLNQLDRLRYSMNSFTRMRYCYPDGRLNMFCKKSPDFVKYPLRPWFLMPSSISKVYSIFFGHWSSLKGTHVPKPFFPLDAGCCWGEELVMLRWEDGKWFSQAYLSKKCI
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: RF3_DESVV
Sequence: MSTRLEREVARRRTFAIISHPDAGKTTLTEKLLLFGGAIQMAGAVKARKSGRHATSDWMAMERERGISVTTSVMQFPYGDHMVNLLDTPGHQDFSEDTYRVLTAVDSALVVIDVAKGVEAQTRKLMDVCRLRDTPVMTFINKLDRDGLPPLDVMADIEENLRIECVPLTWPIGMGSDFKGTYNLLKRELHLFSASHHGRIQEGILIRDLDDPLLDEHLGPQADALRMDLALLEEAGTPFSREKYLRGEQTPVFFGSAINNFGVRELLDNFVDLAPAPRPRPAITREVSPHEESFTGVVFKIQANMDKAHRDRMAFMRICSGTFTRGMKLRHHRVGKDVTVANATIFLAQDRSGVEEAFPGDIIGIPNHGTIKIGDTFTESKEELKFTGIPSFSPEHFRRVRLRNPLKAKQLQKGLEQLAEEGAVQLFRPQVNNDYILGAVGVLQFDVIISRLHDEYSVEAAYEPCSIHTARWLHCNDRKVFAEFCDYYSAELAIDAEGALAYLAPNPWRLESAMERYPAVEFRTTREIR
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINA_RUMCH
Sequence: MRAEILAVGTELLLGQIANTNAQYISSKLPEAGVGVYYHSVVGDNPDRLEDCLKLALKRCDIVITTGGLGPTQDDLTKETISRVCGKKLVLHQESLNDIRNYFSSLGRQMTPNNEKQAYMPEGCIILKNTNGTAPGCIIETGGKIVVMLPGPPAEMKPMFLDYVIPYFKNKGAYSIESVILRVFGIGESAMETKIMDLIDAQTNPTIATYAKEGEVSIRVTASVLKGESADSILIPVVNEIKRRTGDNLYSDKDKTLDAVVAELLTKNNITIGTAESCTGGLISEKLTDIPGISQVFMGGAVTYSNEAKVEYLGVKEQTIKAHGAVSRETASEMAEGIRKRLKTDIGISVTGIAGPGGGTAEKPVGLVYIGLSSESGTVTKELRLSGNRKKIRTITALNVFDLIRRHILKLKIDL
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RL18_CROS5
Sequence: MKTTRKESLKRRHRRIRRKVSGTPDCPRLAVFRSNHHIYAQIIDDVAQHTLAAASTLEPDLRNSLSSGATCEASAAVGKLVAERGMAKGIEQVVFDRGGNLYHGRVKALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MRAY_PECCP
Sequence: MLVWLAEHLAKLYTGFNVFSYLTFRAIVSLLTALVISLWMGPHMIAWLQRLQIGQVVRNEGPESHFSKRGTPTMGGVMILVAIIVSVLMWANLSNPYVWCVLLVLAGYGAVGFVDDYRKVVRKDTKGLIARWKYFWQSVIALVVAFSMYAIGKDTPATQLVVPFFKDVMPQLGLLYVALAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFAGYLHIPYIRHASELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SANA_HAEIN
Sequence: MRFTKSIKFSLKCGRFFIMFTTMLVKKFSPKFTALFRTLLYAIFALIILCLLVDRGISFYVRDKIFTNIDELPFRPCALVLGTSKYTVSGKPNVYYDSRLMAAKSLIEQQKVNYLLLSGDNRTLQYNEPRAMFRDLRKMGVPKTLMFRDFAGFRTLDSVIRADKIFQVKTFTIVSQKFHCERALLIAQAHNIDAICFVAKQPELHFSTQIREVFARIKAVFDLILGVEPYFLGEPQPLPNSTTL
What is the function of this protein?
Participates in the barrier function of the cell envelope.
What are the official names of this protein?
Protein SanA homolog.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: OBG_TROWT
Sequence: MSGITLPEFVDCVTVEFSAGRGGNGCASVRREKYKPLAGPDGGSGGHGGSIFLKADTSERTLISFRRKGHYSASNGAHGLSRLRNGARGKDLEVSVPCGTSVYDEGGRQIADLVSPGSCLQVVRGGTGGLGNAALAGYRRKTPRFALLGLPGQKRKLRLEVKSIADVALVGFPSVGKSSIISAISSAKPKIADYPFTTLHPNLGVVQSGPYRYTVADVPGLVEGASKGIGLGLNFLRHIERCSVVVHVIDCANTQQDPISGFNLIEKELSEYKVAENAIPLNKRPKVIVLNKIDVLQTKEEQDTLLYLQSVFKKLVTDVYAISAVTRSGLRQFTLRLGEICQEYPSQVQPTSQTILIPAKNTPEFSLDRTDGVYRVTGKKPEKWILQTDFSSDEAISYLAERLDRLGIEDALVRAGATCGDEVEIGGVIFTWDPSVANTSFSLSV
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIR2_YEAST
Sequence: MEKNTAPFVVDTAPTTPPDKLVAPSIEEVNSNPNELRALRGQGRYFGVSDDDKDAIKEAAPKCNNCSQRGHLKKDCPHIICSYCGATDDHYSRHCPKAIQCSKCDEVGHYRSQCPHKWKKVQCTLCKSKKHSKERCPSIWRAYILVDDNEKAKPKVLPFHTIYCYNCGGKGHFGDDCKEKRSSRVPNEDGSAFTGSNLSVELKQEYYRHMNRNSDENEDYQFSESIYDEDPLPRPSHKRHSQNDHSHSGRNKRRASNFHPPPYQKSNVIQPTIRGETLSLNNNISKNSRYQNTKVNVSSISENMYGSRYNPSTYVDNNSISNSSNYRNYNSYQPYRSGTLGKRR
What is the function of this protein?
Component of the TRAMP (TRF4) complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information.  Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates like cryptic transcripts generated by RNA polymerase II and III, or hypomethylated pre-tRNAi-Met.  Both complexes polyadenylate RNA processing and degradation intermediates of snRNAs, snoRNAs and mRNAs that accumulate in strains lacking a functional exosome.  AIR2 also inhibits the methylation of NPL3 mediated by HMT1 through its interaction with HMT1.
What are the official names of this protein?
Protein AIR2, Arginine methyltransferase-interacting RING finger protein 2.
What is the protein family that this protein belongs to?
Belongs to the AIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAD_BURMA
Sequence: MVVAVYPGTFDPLTRGHEDLVRRASSIFDTLVVGVADSRAKKPFFSLEERLKIANEVLGHYPNVKVMGFTGLLKDFVRANDARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVEKWLTEKVAAMAQGPSA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL88_HHV6U
Sequence: MNVLVADEWFDCAIRLDSETIAVHEIFNPELSKLLNLHSKTVYMSDLCAFISGCVNRNVGKLTIYWHVNGDIIYALTGILHCVKIKIECGERIADGRYRLYEIPKLFLMRGQSTPMELKWKHAVGIATTNKPLLTHVLTDVLETSPFTLPDTLLSVQELSIFRERLSYIYYVLGSDVDIVARTEREIFQKCAELARLQQVFLIQGNIMENFVLAQACLFQLGADGLWEEISGSVRPRPELMSSAFIQHRVMLNNCYCIAVIFNAIYKHKLSLPTVERSHETVNRVAQEYYKSYVNAPLSVLVCATKVLTLFTEEYNFKSALVFVSQFFQVDVEASRADVIRLFLACLKGD
What are the official names of this protein?
Protein U59.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U59/UL88 family.
Protein: PYRB_ACIF2
Sequence: MSATLRFGEGNLQYDAQGRLRHLLSTEGLRERELLQILDTAESFLSIANRSVKKTPTLRGRTIANLFFENSTRTRSTFELAAKRLSADVLNIAVSTSSASKGESLTDTIDNLMAMQVDGFVIRHPEAGAAHLVARHLGDSALVVNAGDGQHAHPTQALLDVFTIRRLGGPIEDRVVAIVGDVFHSRVARSQIHALSVLGCPEIRVIGPRTLVPEELSALGVHVYHDLQAGLRGVDVICALRLQRERMESHRLPSLDEFHRRFGLTPERLQWAEPGALVLHPGPMNRGVEIASEVADGAQAVILQQVAHGLAVRMAVLAILAGAAGGA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TRMA_CAMC1
Sequence: MDCKYLKECGSCTLFTSYSEQISFKTDLIKQNFSHFYDGKFDLFSSSPKHYRTRAEFGIWHEGSKLSYTMHASEKGKKVFIDECPKVCEQISHLMPRLLESLQDDEILRTKLFGVEFIACKSGTLVTLLYHKKLDSEFEAAMKILASKLDVMILARSRGQKLLSGELNLVDELNVDGQIYKFSLSENAFIQPNKAVNEKMIAWAKECVQSGADLLELYCGHGNFTIPLSFKFKNVLATEISKSSIANALKNCELNGVENIKFLRMDADELMSAFAGVREFNRLKDIKLSDFNFSHVLVDPPRAGLSESVINFIRNFKNIIYISCNPETLKENLNELTKSHKVIKFALFDQFANTHHIECGVLLEAKR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: RL5_GEOSM
Sequence: MARLAELYNKEMVPALMKDQNYKNIMEVPKLVKIVVNMGLGEAIQNVKILDSAAEELAAITGQRPVITKAKKSIAGFKLRQGMPIGCAVTLRRDKMYEFLDRLVSVSLPRVRDFKGISGKAFDGKGNYSLGVKEQLIFPEIDYDKVDKIKGLNITIVTTAKTDAEGKALLKLMGLPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NTDR_BACSU
Sequence: MPTIDEIAKLCNVSKTTVSRVLNNHPYVSKEKRDMILKAINELDYTPNYLARNFRRNKTQTIALSVPSIDHPFFAQLIKGVSHEVLFKNYKVIVFQTFYDKQTELELLELLKHKEVDGIILGTLENEWDQISPFLKYGPILLCNEYHHSADITIIGYDEFEAAYMGVVHLIERGHKKIGFCFDTPYSEAQCQRKEGYLKALQDYNLHHRSEWIFGEMFNIEDGFRVFHKIKDLKDRPSAIFTGNDQVAAGIIKQAMKNGFKVPEDLAVIGFDNQLICQVVTPTITTIDIPVIELGQQAVLKIIESISGNASLNRRIIKLPTKLIIREST
What is the function of this protein?
Positively regulates the ntdABC operon and negatively regulates its own transcription.  Binds to NTD to induce ntdABC transcription.
What are the official names of this protein?
NTD biosynthesis operon regulator NtdR.
Protein: PNP_KLEP3
Sequence: MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGKIPGGFFRREGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQEELKSSKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQIVIQNINDLVKEAGKPRWDWQPEAVNEALNARVAALAESRLSDAYRITDKQERYAQVDVIKSETIATLVAEDETLDANELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQNIDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPTIDEFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPVKAAVAGIAMGLVKEGDNFVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGDKAQHAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQTPSAAAPEAPVAEQGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_SALPA
Sequence: MAKILVLYYSMYGHIETMAHAVAEGAKKVDGAEVIIKRVPETMPPEIFAKAGGKTQNAPVATPQELADYDAIIFGTPTRFGNMPGQMRTFLDQTGGLWASGALYGKLGSVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: TPM_HALRU
Sequence: MDAIKKKMLAMKMEKENAVDRAEQNEQKLRDTEEQKAKIEEDLNNLQKKCANLENDFDSVNEQVQVAMAKLETSEKRVTEMEQEVSGTTRKITLLEEDLERNEERLQTATERLEEASKLPDESERGARVLESRSLADDERIDQLEAQLKEAKYIAEDAERKYDEAARKLAITEVDLERAEARPKAAEAKILELEEELKVVGNNTKSLEISEQEASQREDSYEETIRDLTQRLKDAENRATEAERTVSKLQKEVDRLEDELLAEKEKYKAISDELDQTFAELAGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.