PharMolix/UniProtQA huggingface dataset:
Protein: SPO16_HUMAN
Sequence: MAESGKEKIKWTTTIIISSSLKSYEVATALENRSHKVRYSDSVENGSIIFSLSGVAFLLMDTKECLLSTEEIFLAKIEKFINIHQNSFLVLSAALHGPEEWKLMFRIQQRFLGCNLRILPVHNTVNAINLMCTIAKTTSKPYIDSICYRMITAKAYIIEQSPVWKTLQKIKLNSDSVNPN
What is the function of this protein?
Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells (By similarity).  Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1 (By similarity).  Required for the localization of TEX11 and MSH4 to recombination intermediates (By similarity).
What are the official names of this protein?
Protein SPO16 homolog, Synaptonemal complex reinforcing element.
What are the subcellular locations of this protein?
Chromosome.
Protein: BRE1_CANGA
Sequence: MSSEEPPIKKQKLELSDPDEPLTQHDVISFQKEALFRCLNSKRVELEALTKQYSTVHDKWEQNVHTLATLMSVLSTAASHLRGLCNEESEKTLCDEMINAGESVDKERTDEFLNLLRKYTNSNGSSDSKIDSLGLELQRANKTKSELRLQNKKLTDEIDSLKAYYHGLVRSYDREDSMTVKRVFNKQKTDDNTDNISNTEQRPTSVSPVLTNGATHVKNEVKTEQEALNNHTDSSQSSGITEEEKKKLFLQYENKITDLESHNSSLNRIIEELENYKQLNEKELAQTRLEISNLLSEKHSNEEEREDLLHQIEKLKASNTDLTLTNESFLSKFQELAKEKDTFQEKISSDFEKTLESLKAQNLALEKDLVRVRTTRDELISKVAILEAETSKSVLISDLKQALDILRDQWEKIEFRNNQSPSSDALLKEIQDLESAFKELSSLTHKKYSEYLNHESVISKLTIEKTKADQKYFASMRSKDSILVENKNLSKSLNKANELILQLKDTDKLYKQKIESLHKQLALSQNNEKRLVDSNKAANLKVMNLNSEIQKQKKLLDFTSSQKNELINELTEANGMLKSKELEIEFKENELQTALKKNEKLEEFLSKENYNMNKPSSLATTNLDEDSMAEELENFRTLVYCSLCSKNWKNMAIRTCGHVFCEDCCKERLAARMRKCPTCNKPFSSNDLLMVHL
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1.  H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.
What are the official names of this protein?
E3 ubiquitin-protein ligase BRE1, RING-type E3 ubiquitin transferase BRE1.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CD80_MOUSE
Sequence: MACNCQLMQDTPLLKFPCPRLILLFVLLIRLSQVSSDVDEQLSKSVKDKVLLPCRYNSPHEDESEDRIYWQKHDKVVLSVIAGKLKVWPEYKNRTLYDNTTYSLIILGLVLSDRGTYSCVVQKKERGTYEVKHLALVKLSIKADFSTPNITESGNPSADTKRITCFASGGFPKPRFSWLENGRELPGINTTISQDPESELYTISSQLDFNTTRNHTIKCLIKYGDAHVSEDFTWEKPPEDPPDSKNTLVLFGAGFGAVITVVVIVVIIKCFCKHRSCFRRNEASRETNNSLTFGPEEALAEQTVFL
What is the function of this protein?
Involved in the costimulatory signal essential for T lymphocytes activation.  T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
What are the official names of this protein?
T-lymphocyte activation antigen CD80, Activation B7-1 antigen, B7.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: VU55_HHV6Z
Sequence: MLFKNTLAYYNFSITYTQDYKNTPRLNTRVLHPSCKITSSLKKTQYLKSKVKHKMFFCTNMYSPQLNHVLQLVFDCNHIVPNSYQEITLKCRISSTKPGILFITDGTESETEDVLFDVQFLENTMTIKIKILPISRTVPVRIHLFSIPIYLPSPALEIDDINALCQKENIDPIVYEQYGLTNMPISTTNVINQFKVVSNDSVETSLILLNLSWTESPYQSQKLDRYGRKLLIVFSVFSIDTRKCSYWKNLFKSMIPLCRVNMISEPGISIYKIEFNDPFLTIFLRNVVLPENERRFPITKECYLRLTFSPPNRSTVTLNMNMPYFKICADGKSLEVFFPSDMSLVINTNKEITLRGKFTNKKIVGIFIPVQTHVFKLYPFLWFAQEPLKLRISCEKTVSVTEHDMLGRIFFVTKKLFRKPFRSLSNSDMKSLLTHTENTDKPFEVHFMGNCFPAYLLPELTLHPLEYEDKPARGNPQILPSVEKHSIIKMRI
What are the official names of this protein?
Uncharacterized protein U55.
Protein: CRG12_LITCT
Sequence: MGKIIFYEDRNFQGRSYECSNDNPDLQPNFNACNSVRVENGCWMIYERPNYMGHQYFLKRGEYPDYQQCQGLNDSPQSSRLLSQNLGIGTNKLRVYERGDSKGEMMEFLEDCPNVYDRFCSHEIHSCNVLDGYWIFYELPNYKGKQYLLRPGEYKRFTDWGSQTAKVGSFRRVIGIC
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin M1-2, Gamma M1-2.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: RS16_FRATN
Sequence: MVVIRMARGGAKKRPFYRIVVADKRSPRDGRFIEKLGFFNPLAKGGEERLKLDVAKAEAWLAKGAQPSDRVASLIKEAKKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ARLY_MYCVP
Sequence: MSTNEGSLWGGRFADGPADALAALSKSTHFDWVLAPYDVVASKAHARVLFRAGLLTEEQRDGLLAGLDSLGSDVADGSFGPLVSDEDVHGALERGLIDRVGADLGGRLRAGRSRNDQVATLFRLWLRDAIRRVADGVLEVVAALATQAAAHPTAIMPGKTHLQSAQPVLLAHHLLAHAHPLLRDVDRLADFDKRAAVSPYGSGALAGSSLGLDPDAIAEELGFAAAADNSIDATASRDFAAEAAFVFSMIGVDLSRLAEDIILWSTTEFGYVTLHDAWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGLVGTLRFDVDRMAELAPLGYTLATDVAEWLVRRGVPFRVAHEAAGAAVRAAEARGIGLEDLADAELTGIHPQLTADVREVLTTEGSVNSRDARGGTAPTQVARQLSAVRDTSERFRVRLRR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_HELPG
Sequence: MQQAPVVLSTLDKLLNWGRSNSLWPLTYGLACCAIEMMATGGSRFDFDRFGTIFRASPRQSDVMIIAGTLTKKHAEFMRRLYDQMPEPKWVISMGSCANTGGMFNTYATVQGADRIVPVDIYLPGCAPRPETLQYALMVLQDKIRRSKAIKQDAPKRLV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS6_STRT2
Sequence: MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWEKRRLAYEIQDFREGLYHVVNVEANDATALNEFDRLSKINGDILRHMIVKLDA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: ATPF_RHDSA
Sequence: MNDFLLISSLAELSSETKKSFGFNPNFLEANVLNIAILLSGVVYLGRNFLTSALEVRQQKVAEAIQEAEERLVQANSRLLESEKQLTQAQAVIEEIKKEAEKTARTVKESILAQGKLDIERLTNNGKSSIEKAELQIKKQIQQHITELAIQKVTVQLKEYMTPNLQSKVIDSNISNLGGQL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RRP36_YEAS8
Sequence: MSYYFKNLKPDLNSDVEEDDGNLLESIMANKSKREIDEQESSDDELKTLSFGSLKKAETIIDEEDFKDTKPVHKKPITTTYREESFDEDDDSEDKSDEDAGFFEEDSEDETHHGQKVPKKKSKHAPIEQSSKKRVPRVRNIPGLEIPRNKRSNLYQDIRFDKSTGKALDSSIIRKRYQFLDEYREKEIDELQKLLQDRKFLSKIDQGEREEMEQRLKSMKSRLQSMKNKDLEREILKEYESDMNKNNNTRYHLKKSEKRKVVQKWKFDHMKAKQREKVMERKRKKRLGKEFKQFEFHNRR
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y025_LISMO
Sequence: MGLTFFDKARELTEELEKTQAESIHQAAKLVADSIMNDGIIQAFGSGHSYAAAIEVCGRAGGLIPSKVIMDPAGGYYESIEGVGSLLTHRLQAKPNDIFFLISNSGRNPMGIELAEWIKSQGCKLIVVTALDASQTAASRHSSGKLLYEFADVILDNRSVQGDAALELEGLEGKVCGTSSFSAVLLLQQTIYEAVELMLEKGYTPPVYRSANIDGGYEYNFAIEDKFADRIFHL
What are the official names of this protein?
UPF0309 protein lmo0025.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.
Protein: PPAX_BACAN
Sequence: MKINTVLFDLDGTLINTNELIISSFLHTLHTYYPNQYKREDVLPFIGPSLHDTFSKIDESKVEELITSYRQFNHDHHDELVEEYETVYETVQELKKQGYKVGIVTTKARQTVEMGLKLSKLDEFFDVVVTIDDVEHVKPHPEPLQKALQLLDAKPEEALMVGDNHHDIVGGQNAGTKTAAVSWTLKGRAYLETYKPDFMLDKMSDLLLILSDMNRS
What is the function of this protein?
Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P.  Might play a role in controlling the intracellular pyrophosphate pool.
What are the official names of this protein?
Pyrophosphatase PpaX.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PpaX family.
Protein: ATPE_CLOPS
Sequence: MNKFKLIVTTPERVLISGEVSRVLCKNAVGEFEILAGHQPYLTATVPTVTRIDDENGESKYLFTSTGLMKVQNNEVTFCVNSAEWPEEIDEARAMNAKQRAEERLKNKTDELDKKRAKLALARAMSRLKLKEM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PRM2_RATTU
Sequence: MVRYRMRSPSESPHQGPGQDHESEEQGQGQELNPERVEDYGRTHRGHHRHRRCSRKRLHRIHKRRRSCRRRRRHSCCHRRRHRRGCRRSRRRRRCRCRKCRRQCH
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-2, Sperm histone P2, Sperm protamine P2.
What is the protein family that this protein belongs to?
Belongs to the protamine P2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DNAJ_SALTI
Sequence: MAKRDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDAQKRAAYDQYGHAAFEQGGMGGGFGGGFNGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMDLTLEEAVRGVTKEIRIPTLEECDVCHGSGAKAGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCHKCHGHGRVEKSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVMLKVPSETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLSEKQKQLLKDLQESFGGPTGEKNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEP89_DROME
Sequence: MSTRNVMITDLDQPDPNQQQHHQNPKKNRKVLQTLSGNFNRRSRSVEVEVKRQDNLGVVHKDRKKDRSFNSLLQAKDQQLEQLVQRLATLHRYNDQFAKENDQLRKDSGQLERRLTEAEQQVANCSRCQQLGQRLDTVLAQNRTLAGDVDMLKTLVFRLNVQIESYQDQRRLGEGAPTCGGSTKVSSSSAPYPPLPTHTLGPLLQAYDESLRDKDALLAQYNTEFEHFTGELKRALEENTKLLQSQEQLRRDLGGWREERVCLQAQLGVCRSKAEAQTRKTDLAKEKLVEVMHCYEQRMQTLILDMDHLQAAYARTKSELAALKSASSAAPAAVAPPVPAESEALHQCKALLEQLRQEHARERTCLQEQLQATTARAASLVRSTEKAKHSRDRLKARLRMALQWAQKLEAGQAEVRDTYEAVRRLEVLVQHKESQLRGLHARNAEEMDKLRHKLQQKEETICALLRGKMERRPAVD
What is the function of this protein?
Required for mitochondrial complex IV activity.  May be involved in non-associative learning.
What are the official names of this protein?
Protein Cep89 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space.
Protein: NADE_MESFL
Sequence: MELKEYLDYLVEFIKETVKKANAKGVVIGISGGIDSAVVACLAKKAFPNDYTAVWMPIESSDEDYKCKQELIDQCGIKAIDVELKETFLSFKKAIKDSTTPEHKLAIANAKARLRMTTLYTVAQTNSYLVLGTDNLDEWHIGYFTKFGDGGVDMVPLVHLLKREVREAARILGVPTSIINRAPTASLWEDQTDESELGITYDQIDAYLAGEINDENVKSRVDHLHKISEHKRNGAVAPKEFKRK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: ACKA_BUCCC
Sequence: MKKKLILVLNCGSSSVKFSIIDVIEGVLYISGIANTINNVSFLKIYDIKKKIKIVKKNISTDSYKKLILLICDLLFIHFNKYLKLIIGIGHRIVHGGKDIKKSMIINKKILLKIKKSAIFAPLHNPYHLIAIKIILNKFVKLKNRNVAVFDTSFHQTMPKKSFLYGIPYSFYKKYSIRKYGAHGINHFYITHECSLFLKKSTNNLNIISCHLGSGSSITAIVNGKSIDTSMGLTPLEGLVMGTRCGDIDPYIIIYMIKKLNFSITQIQKILTKSSGVLGISSITSDFRELEKKYYSHKKAKLAIDIFCRRVSKYIAGYSSLMPKGKLDAIVFTGGIGENSSFIRKKIIKNLSIIGFFLDIEKNLIKTGNNNRFIHTINSKPILVIPADENKIIAKETYNILIKNNF
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP1_ARATH
Sequence: MPIGVPKVPFRSPGEGDTSWVDIYNRLYRERLFFLGQEVDTEISNQLISLMIYLSIEKDTKDLYLFINSPGGWVISGMAIYDTMQFVRPDVQTICMGLAASIASFILVGGAITKRIAFPHARVMIHQPASSFYEAQTGEFILEAEELLKLRETITRVYVQRTGKPIWVISEDMERDVFMSATEAQAYGIVDLVAVQ
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
Chloroplastic ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase ClpP1, pClpP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ALH13_CAEEL
Sequence: MFRATRCLRLPLRNSHINILRPTQTELIKTRSSALAPYEKVSPITAVGATPVGVGNGNYCYSTKTRQKHPLINTRNDLKKAQRVVVKLGSAVITREDECGLALGRLASIVEQVSELQQSGRQMLIVSSGAVAFGRQKLRQELVMSMSMRQTLRGPSGMTADKRACAASGMPGLMSLYEQLFQQYGITVAQVLLTKPDIDDDQRRKNLQATIESLLSLNIIPIVNANDAVAPDPKLNMHISDNDSLAARLSAEIEAELLIILSNVNGVYTGPPDLEGSRLLYTYVPSENSGVTFGANSKFGTGGMESKVTACVNALNNGVTTVITNGLAQDAITDAVAGKKIGTMFCNTKGYEGPPIEEVAEKCRDAGRQLAALSNKERGAMVRHLAALLVDKEKYIIEANQTDLANAKSAGLDPQLLNRLKMTPEKIQDLHAGLNTIADSAETLVGRVLKKVKISEGLFLEQVTVPIGSLMVIFESRPDCLPQVASLAMASGNALLLKGGKEAEESNKALHALVQEALGTHGFEMRDAVTLVRSREDVADLLQLKDLIDLIIPRGSSDLVRSMQEKSKGIPVLGHAEGVCHVYIDKDCDEQKAIQIVRDSKCDYPSACNAAETILIHKDLATAPFFDSLCSMFKAEGVKLHAGPKLAALLKFAPPPAESMSFEYGSLECTLEVVDNVEEAVAHIIRYGSGHTESIITENTNTAEHFLKHVDSACAFHNASTRFADGYRFGLGAEVGISTGRIHARGPVGVEGLLTTKWLLRGEGHLVEDFKNGKYSYLHENLNPSEVYRALDAAGELKKATA
What are the official names of this protein?
Probable delta-1-pyrroline-5-carboxylate synthase, P5CS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
Protein: FLAB3_THEKO
Sequence: MRFLKKRGAVGIGTLIVFIAMVLVAAVAAAVLINTSGYLQQKSQSTGRQTTEEVASGIKVTSIVGYAPYDDSNKVYKPISKLAIYVSPNAGSAGIDMKKVRVILSDGSIEAVLKYDNSDADSDGTLDKDVFAVGMPDNVFEDDTGTTAYDGDQYITWSELNDKTFGIIVVQDSDGSLKPLTPTLNKGDIAIIAVRVGNYYVDSNGNLQAYSPTPDGVFGEGIKPNTHITGQVVPEHGAPGVIDFTTPSTYTQSVMELQ
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
What are the official names of this protein?
Flagellin B3.
What is the protein family that this protein belongs to?
Belongs to the archaeal flagellin family.
What are the subcellular locations of this protein?
Archaeal flagellum.
Protein: SECB_SHEPW
Sequence: MAEVANNEEQAPQFNIQRVYTKDISFETPNSPAVFQKEWTPEVKLDLDTRSNKLSDDVYEVVLSLTVTAKNGEETAFLCEVQQAGIFAITGLTEQQLAHSLGAYCPNVLFPYAREAVGSLVSRGTFPQLNLAPVNFDALFAQYVQQRQAAAAEAPAEEANA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_STRT2
Sequence: MEENIVSENNMKHRSSVYDSMVKSPNRAMLRATGMTDDSFEKPIVGVISTWAENTPCNIHLHGFGQIAKEGVKDAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDIIADSIEAAMGGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLNGKDIDLVSVFEGIGKWNHGDMTAEEVKNLECNACPGPGGCGGMYTANTMATAIEVMGMSLPGSSSHPAESAEKKADIEEAGRAVVKMLEMGLKPSDILTREAFEDAITVTMALGGSTNATLHLLAIAHAANVDLTLEDFNDFQERVPHLADLKPSGQYVFQDLYNVGGVPAVMKYLLKNGFLHGDRITCTGKTVAENLEAFDDLTPGQKVIMPLENPKRADGPLIILKGNLAPEGAVAKVSGVKVRNITGPAKVFDSEEDAIEAVLSDEIVDGDVVVVRFVGPKGGPGMPEMLSLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQVGGPIAYLRTGDMVTVDQDTKEITMHVPDEELAKRKAETELPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGKA
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CH60_LEPBA
Sequence: MAKTIEFDETARRKLLSGVNKLANAVKVTLGPKGRNVVIDKKFGSPTITKDGVTVAKEIELEDAIENMGAQMVKEVSTKTNDIAGDGTTTATILAQAIINEGLKNVTAGANPMALKHGIDKAVVVAVEEIKKHAIKINSKAEYANVATISANNDPEIGNLIAQAFDKVGKEGVITVDEAKSIETTLDIVEGMQFDRGYVSPYMVTDPEAMIATFNDPFILIYDKKIASMKDLLPVLEKIAQAGRPLVIIAEEVEGEALATIVVNTLRKTIQCVAVKAPGFGDRRKAMLEDIAILTGGQVISEDLGMKLENADVKMLGRAKKVVVDKENTTIIEGAGASKDIQGRVNQIKKQIEDTTSDYDREKLQERLAKLAGGVAVIHVGAATEVEMKEKKARVEDALSATRAAVEEGIVPGGGLTLLRAQDAVKALKLVGDEQTGANIILRALEEPIRMITSNAGLEGSVIVEQARARKGNEGFNALTMVWEDLIKAGVVDPAKVVRSALQNAASIGAMILTTEVTITDKPEPKDASGAGMGGMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_SALPB
Sequence: MAKLHDYYKDEVVNKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GLPK_FRATM
Sequence: MSKDFILAVDQGTTSSRAIIFDKKGNIRKIAQKEFTQIYPKSGWVEHDAMEIWGTQSGVMREALEFGRVKPDQIAAIGITNQRETVIVWDKETGDPVYNAIVWQCRRTSSICDEIKRDPQFVKYIKENTGLVVDAYFSGTKVKWILDNVEGAREKANAGKLLMGTIDTWLIWNLTRGKVHATDYSNASRTMLFNINSLEWDKKILDYLNIPESMLPEVKNSSEVFGVTDSHTLGGAEIPIAGVAGDQHAALFGHCCFEKGMAKNTYGTGCFALMNVGDKPVYSDEGLLTTIAWAENGKPTYALEGSVFIAGAVIQWIRDGLGLVRSAEDSEYYATKIDSTNGVYLVPAFVGLGTPYWDMYARGTIVGITRDTKREHIIRAALEAIAYQAKDVLECMKEDTGLDLAGLRVDGGAVQNNFLMQFQSDILQSEISKPKINEITGLGAVFLAGLAVGFWKDKQELKSILTTEKVFEPQKDSQAVAHDYRGWKKAVERSKAWAECYS
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: PDS5_YEAST
Sequence: MAKGAVTKLKFNSPIISTSDQLISTNELLDRLKALHEELASLDQDNTDLTGLDKYRDALVSRKLLKHKDVGIRAFTACCLSDILRLYAPDAPYTDAQLTDIFKLVLSQFEQLGDQENGYHIQQTYLITKLLEYRSIVLLADLPSSNNLLIELFHIFYDPNKSFPARLFNVIGGILGEVISEFDSVPLEVLRLIFNKFLTYNPNEIPEGLNVTSDCGYEVSLILCDTYSNRMSRHLTKYYSEIIHEATNDDNNSRLLTVVVKLHKLVLRLWETVPELINAVIGFIYHELSSENELFRKEATKLIGQILTSYSDLNFVSTHSDTFKAWISKIADISPDVRVEWTESIPQIIATREDISKELNQALAKTFIDSDPRVRRTSVMIFNKVPVTEIWKNITNKAIYTSLLHLAREKHKEVRELCINTMAKFYSNSLNEIERTYQNKEIWEIIDTIPSTLYNLYYINDLNINEQVDSVIFEYLLPFEPDNDKRVHRLLTVLSHFDKKAFTSFFAFNARQIKISFAISKYIDFSKFLNNQESMSSSQGPIVMNKYNQTLQWLASGLSDSTKAIDALETIKQFNDERIFYLLNACVTNDIPFLTFKNCYNELVSKLQTPGLFKKYNISTGASIMPRDIAKVIQILLFRASPIIYNVSNISVLLNLSNNSDAKQLDLKRRILDDISKVNPTLFKDQIRTLKTIIKDLDDPDAEKNDNLSLEEALKTLYKASKTLKDQVDFDDTFFFTKLYDFAVESKPEITKYATKLIALSPKAEETLKKIKIRILPLDLQKDKYFTSHIIVLMEIFKKFPHVLNDDSTDIISYLIKEVLLSNQVVGDSKKEIDWVEDSLLSDTKYSAIGNKVFTLKLFTNKLRSIAPDVPRDELAESFTEKTMKLFFYLIASGGELISEFNKEFYPTPSNYQTKLRCVAGIQVLKLARISNLNNFIKPSDIIKLINLVEDESLPVRKTFLEQLKDYVANELISIKFLPLVFFTAYEPDVELKTTTKIWINFTFGLKSFKKGTIFERALPRLIHAIAHHPDIVGGLDSEGDAYLNALTTAIDYLLFYFDSIAAQENFSLLYYLSERVKNYQDKLVEDEIDEEEGPQKEEAPKKHRPYGQKMYIIGELSQMILLNLKEKKNWQHSAYPGKLNLPSDLFKPFATVQEAQLSFKTYIPESLTEKIQNNIKAKIGRILHTSQTQRQRLQKRLLAHENNESQKKKKKVHHARSQADDEEGDGDRESDSDDDSYSPSNKNETKKGHENIVMKKLRVRKEVDYKDDEDDDIEMT
What is the function of this protein?
Essential for the establishment and maintenance of sister chromatid cohesion at centromere proximal and distal regions during S phase.  Also required for chromosomal condensation.
What are the official names of this protein?
Sister chromatid cohesion protein PDS5, Precocious dissociation of sisters protein 5.
What is the protein family that this protein belongs to?
Belongs to the PDS5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COPB_STAAT
Sequence: MNHSNQMHHDNHASHDHHSGHAHHHGNFKVKFFVSLIFAIPIILLSPLMGVNLPFQFTFPGSEWVVLILSTILFFYGGKPFLSGGKDEIATKKPGMMTLVALGISVAYIYSLYAFYMNNFSSATGHTMDFFWELATLILIMLLGHWIEMNAVGNAGDALKKMAELLPNSAIKVMDNGQREEVKISDIMTDDIVEVKAGESIPTDGIIVQGQTSIDESLVTGESKKVQKNQNDNVIGGSINGSGTIQVKVTAVGEDGYLSQVMGLVNQAQNDKSSAELLSDKVAGYLFYFAVSVGVISFIVWMLIQNDVDFALERLVTVLVIACPHALGLAIPLVTARSTSIGAHNGLIIKNRESVEIAQHIDYVMMDKTGTLTEGNFSVNHYESFKNDLSNDTILSLFASLESQSNHPLAISIVDFAKSKNVSFTNPQDVNNIPGVGLEGLIDNKTYKITNVSYLDKHKLNYDDDLFTKLAQQGNSISYLIEDQQVIGMIAQGDQIKESSKQMVADLLSRNITPVMLTGDNNEVAHAVAKELGISDVHAQLMPEDKESIIKDYQSDGNKVMMVGDGINDAPSLIRADIGIAIGAGTDVAVDSGDIILVKSNPSDIIHFLTLSNNTMRKMVQNLWWGAGYNIVAVPLAAGILAFIGLILSPAIGAILMSLSTIIVAINAFTLKLK
What is the function of this protein?
Involved in copper transport.
What are the official names of this protein?
Probable copper-transporting P-type ATPase B.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.