PharMolix/UniProtQA huggingface dataset:
Protein: GLI1_XENLA
Sequence: MASRQCPPAAVFNSMNPPVNSYVEHCYLRSPNVMAEGMNEMPYCHQTNLMTSHHGFGLAQGSDHLAGTDGSRFSTPRSTMKLSKKRAMSISPLSDASIDLQTMIRTSPNSLVAFINSRCSSASGSYGHLSIGTISPSLGYQNCLNHQRPQAGPYGSNPLMPYNSHEHLSSRGMSMLQPRSSVKHCQLKSEPLSITGLDTIGSKRLEDGSEGDISSPASVGTQDPLLGLLDGRDDLEKDDGKHEPETVYETNCHWESCTKEFDTQEHLVHHINNEHIHGEKKEFVCHWQDCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHITKKHRGDGMLRAQPGHEGPGNQNVKGENQLDMEASSACKEDGRLAVPDITLKSQPSPGGQSSCSSERSPLGSTNNNDSGVEMNANTGGSFEDLTNLDDIPSVDSMGTAGASALRKLENLRIDKLNQLRKTPSSGKMVKLPSIHNSGPQGDMSVVCGPLGMSHNQHGIELPASSHVNHLNDRRNSTTSTMSSAYTVSRRSSVVSPYLPNQRAGDSGNMVDSYDISTDPSGHSNEAVCASGLPGLTPAQQYRLKAKYAAATGGPPPTPLPNMERMNTNNRMAFASSDYRGSAISSLQRRHSSNEYHNYGTGIIHPAQAPGAGIRRASDPARTGGDIQAVPKVQRFKSMTNMNVSMMGRQGTSIQQAYGGSDANLQRHMFSPRPPSITENVFMETAGPDEVCHTKEQGFIQSNEMQHYMNYQGQGSQLTAPNDHMNFNPQIHGLDGQSQNVYSHSQRAISNMHLNAENYSGQSNVSNFNQCQMTAHNQHFQNTRQAYNCANLPVQWNEVSSGTMDNPVQRPNHQIMHQNMSPGNHCQSQLSNCTVPESTKQGCPVNRNSCQQGMYMNNQKYNHGGQVQVKPEQQFHHSAPAMMSCQNMKHPSRQEHHFTKTNTMPLSSEATNCDYQGQQDSTQNSCFNVGLNLNLLSPPGRRSQTPIMQVKEIMVRNYVQSQQALMWEQHPKSMAMMTNSGDDVDTRQNQHKNTLNAAVYMGPKYMNYQGKPSPNNLMSPSSQDSQSSHTKAMGSPSSQCYNFDMMPHPPCGPKPLSRQHSVSSQSTYMGSPNQLSPSYQSSESSPRRMACLPPIQPQSEVTNNTSMMYYTGQMEMHQSKPGVHKLTTPLNLNQTSCDGHQHGQYNASHSFLKTVPYTSSCPAANTLDSLDLENTQIDFTAIIDDADNALMPGNISPNVLAGSSQASSHLTTLRNTGAVVPNMVVGDLNSMLSSLAGENKYLNTM
What is the function of this protein?
Acts as a transcriptional activator.  Binds to the DNA consensus sequence 5'-GACCACCCA-3' (By similarity).  May regulate the transcription of specific genes during normal development (PubMed:9216996).  Mediates SHH signaling (PubMed:9216996).  Plays a role in cell proliferation and differentiation via its role in SHH signaling (By similarity).
What are the official names of this protein?
Zinc finger protein GLI1, GLI-1.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL302_ARATH
Sequence: MVTEKKTKKSHEGINSRLALVMKSGKYTLGYKSVLKSLRGSKGKLILISTNCPPLRRSEIEYYAMLAKVGVHHYNGNNVDLGTACGKYFRVSCLSIVDPGDSDIIKSIPGDQ
What are the official names of this protein?
60S ribosomal protein L30-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: GLRX3_SCHPO
Sequence: MANRKIFLITSLIISLLLIHIFIFSPLNEPEKNAKAGPLGLSDVSVPSAPKLPAKDSTDFEVFLENPVIIFSRPGCPYSAAAKKLLTETLRLDPPAVVVEVTDYEHTQELRDWLSSISDISTMPNIFVGGHSIGGSDSVRALYQEEKLQSTLDEWTHNKVLILPTD
What is the function of this protein?
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (By similarity).  Binds one iron-sulfur cluster per dimer.  The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit (By similarity).
What are the official names of this protein?
Monothiol glutaredoxin-3.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. Monothiol subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS18_SALA4
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RN166_XENLA
Sequence: MAMFRNLVASSQHRQHHSHQSLATPSSADSLETQFGCPICLEVYYKPVAIGSCGHTFCGECLQPCLQVSSPLCPLCRMPFDPKKVDKASNVDKQLSSYKAPCRGCSKKVTLAKMRAHISSCPKVQEQMANCPKFVPVLPTSQPIPSNIPNRSTFVCPYCGARNLDQQELVKHCMENHRNDPNKVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAALQAALALSLSEN
What is the function of this protein?
E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF166, RING finger protein 166, RING-type E3 ubiquitin transferase RNF166.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_GLAPA
Sequence: RFKKIRRLGALPGLTSKRPRSGSDLKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQILLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKNKQRSKALIQNFIASSPHQEELPNHLTIDPFQYKGLVNQIIDSKWIGLKINELLVVEYYSRQTDL
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPIS_LACAC
Sequence: MSRTPIIAGNWKLHMNPEQTTEFVDAVKGKLPDPSKVESLICAPAVDLDALRKAAEGSNLHIGAENCYFEDEGAYTGETSPKVLKEMGIDYVIIGHSERRGYFHETDEDINKKAKAIFANGMKPIICCGESLETREANKQEDWVVAQIKAALDGLTAEQVSSLVIAYEPIWAIGTGKTASSDQAEEMCKTIRETVKDLYNEETAENVRIQYGGSVKPANVKELMSKPDIDGGLVGGASLDPESFLALVNYQD
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NORM_RHILO
Sequence: MSAIDAGARAPENLWRQEIRATLALAWPMVLTNLGQTAMTATDVMMMGRLGPDTLASGALGANLYFMPLIFGLGLMLATSPMIATELGRRRYSVRDLRRTVRQGLWLAILISIPIWIVLWHGEAILLAMGQEPALAHQAGIYLRWLEWAVLPFYGYIVLRSFISALERPGWALIIVFVAVACNALFNWVFMFGNLGFPAMGIAGSGLATSLSSTLMFAGMAAVVMLEKKFRRYRLFGRFWRSDWPRFNGLLRLGLPIAGILAFEVTIFNAAALLMGLIDADSLAAHAIAIQIASISFMVPLGLNQAVTVRVGLAHGAGNPEGVSRAGWTAFVIGVSFMALMGLVMVLWPHLLISAFIDLANPANARVIALAVSFLVFAALFQVFDGAQAVAAGMLRGLHDTKVPMIYAAIGYWGVGLPLGVLLAFHFGFHGVGIWIGLSSGLAVVAALLLTRWLRRDRIAPPLAFGH
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSPA_GEOSW
Sequence: MLHRYLPMTEEDKREMLKVIGVDSIDDLFADIPESVRFRGELNIKKAKSEPELFKELSALAEKNADTKKYTSFLGAGVYDHYIPVIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMICELTGMDVANSSMYDGGTALAEAMLLSAAHTKKKKVLLSKTVHPEYRDVVKTYAKGQRLCVVEIPFQNGVTDLEALKMEMDEEVACVIVQYPNFFGQIEPLKDIEPIAHSGKSMFVVASNPLALGILTPPGQFGADIVVGDAQPFGIPMQFGGPHCGYFAVKSALIRKIPGRLVGQTSDEEGRRGFVLTLQAREQHIRRDKATSNICSNQALNALAASVAMTALGKKGVKEMAAMNIQKAQYAKNELVKHGFHVPFPGPFFNEFVVRLEKPVAEVNKRLLEKGIIGGYDVGRDYPELQNHMLIAVTELRTKKEIDTFVKELGDCHA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: OCA5_LACTC
Sequence: MTDRKTLVHSHLHWRNVKRKHWQKDLVAKVVELIKVGDHDALALVARTAGIPPQLRKHVWPVLLKFHPMVVSPNIMSNTLVWDSQHQKWHYHPEIRSEDEIRDQMAHDLGKYFHKRTSAGKRAQSAASGPGAAPGGDLSPLPPGQQRVVAALQQCILKFLQKWAQFFKYESGLAWIALALAEWCPLDGGEDVLPGKRHGAPVNLYHEYFLPEEIRDQLPSESEFAFDELFERLVLVILHSPDIPKAERLARAESEMTSVLQYYPVISGGDLSFQCQLFFKVFSVILPELYQPVSDEETLRPSKKTNWMYWWFKCSGARVFHKQDRARIWDTLLGWRPHPRSLNFYLNYNSKLFDHLYSTRTSSALDSEFFHKICKYGHDAFWFPDLDSLSLGSQDLKCDFQVLSELVRRNKYDNSDDELEITPKNNGTVGSKIKKGVEIPFSLLDPHVQLIFIYMAILQQHEFKLLEFEEAEISEFFNNVPSLSRADDHNYRSLYEEEIESRSVSSSETEPEDLFKRPGSSASTPHMLIEVGDDDKASKSFDDLYNLAGDIWRKWIWRELEDNAGT
What are the official names of this protein?
Oxidant-induced cell-cycle arrest protein 5.
What is the protein family that this protein belongs to?
Belongs to the OCA5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETA_BRUSI
Sequence: MEADFVIIGSGSAGSAMAYRLSEDGRYSVIVIEYGVPDVGPLIQMPAALSFPMNMETYDWGFSSEPEPHIGGRSLVTPRGKVLGGSSSINGMVYVRGHACDFDHWSQSGARGWAYADVLPYFKRMENSQGGQEGWRGTNGPLYVQRGKRDNPLFHAFVEAGHQAGFEVTDDYNGEKQEGFGPMEQTIHNGRRWSAANAYLKPALKRPNVKLVKGFARKIVLEGKRAVGVEIEAGRTFSTIRARREVIIAASSINSPKLLMLSGIGPAAHLKEHGIDLVADRPGVGQNLQDHLEVYIQQECTQPITLYSKLNLFSKARIGVEWLLFKTGDGATNHFESAAFVRSKAGVEYPDIQYHFLPVAIRYDGKAAAQSHGFQAHVGPMRSKSRGSVTLRSANPREKPVIKFNYMSHEDDWADFRHCVRLTREIFGQAAFDPYRGAEIQPGAHVQTDDEIDNFIREHVESAFHPCGTCKMGAVDDPMAVVDPECRVIGVEGLRVADSSIFPRITNGNLNGPSIMVGEKASDHILGRTPLARSNQEPWINPRWQVSDR
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: CA4B_CONST
Sequence: MGMRMMFTVFLSVVLATTVVSTPSDRASDGRNAAVHERQKELVPSVITTCCGYDPGTMCPPCRCTNSCPTKPKKPGRRND
What is the function of this protein?
Kappa-conotoxins bind and inhibit voltage-gated potassium channels.
What are the official names of this protein?
Kappa-conotoxin-like SIVB, S4.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL37_EMENI
Sequence: MTKGTSSFGKRHNKTHTLCRRCGRRSYHIQKSTCANCGYPAAKTRKYNWSEKAKRRKTTGSGRTAHLRDVHRRFKNGFQVGTPKGARGPENH
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
60S ribosomal protein L37.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: MDTC_EDWI9
Sequence: MSGFALFINRPVATSLLALAITLVGLLGLRLLPVAPLPQVDFPVIMVSASLPGASAETMAASVAMPLERALGRIAGVNEMTSSSSLGTTRIILQFNLDRNIDGAARDVQAALNAAQSLLPSGMPSRPSYRKANPSDAPIAILTLTSAQYSQGDLYDLASTRLAQKIAQINGVGDVSVSGSSLPAVRIDLNPDALFNQGTSLDTVRQAIASANVRRPLGAVADDGRRWQVQSNDALMTAQEYRPLIIRYRDGAPLRLQDVARISDGVEDVRNAGMSNGQPAILIMIRRSADANIIETVDRLRSDLPALQALLPGGVSLDIAQDRTPTIRASLREVEQSLAIAIALVILVVFLFLRSARATLIPAVTVPVSLIGTCAAIYLCGFSLNNLSLMALTIASGFVVDDAIVVLENIARHIEDGLSPHRAALAGVREVGFTVFSISLSLAAVFIPLLFMGGIPGRLFHEFAITLSASIAISLLIALTLTPMMCARLLRPRHTDGGMRPTALRRLSALLQRGYALSLNWTLDHARWVLLTLLAVIGLNIWLYISIPKTFFPQQDTGRLMGFIQADQSISFQAMRGKLQDFMHIVRADPDVDNVTGFTGGTRVNSGMMFIALKPLGERKQDAQQVIARLRTRLSHEPGANLFLMAVQDIRAGGRQGNASYQYTLLSDDLAVLRHWEPQVRKALAALPQLTDVSTDQQDKGTEMLLTYDRPAMARLGIKVSEVNTLLSNAFGQRQISTLYQPLNQYHVVMEVDPRYAQDERALDKMFIINQAGQPIPLSGFASWLPANAPLSVNHQGLSAAATISFNLPPGGSLSDASDAIAHAMTALGTPPSLRGTFAGTALLFQQAQSSQLLLILAAIATVYIVLGILYESYIHPLTILSTLPSAGVGALLALMLFNAPFSLIALIGIMLLIGLVKKNAILLVDFALTAEREQHLSARDAIYQACLLRFRPILMTTLAALFGALPLAFSYGDGAELRQPLGITIVGGLLVSQILTLYTTPVVYLYMEKLRARFSRQKALPPLAY
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUED_RICCN
Sequence: MIKCTRRIEFDAGHRIIEHQNKCQFLHGHRYVLEIAIAANKTDKLGMVIDFGLIKDLAKKWIDENFDHSLILHQDDKEMGQQIENCTGQKIYYMQNNPTAENIATHLKNEIFPKLFVSQNFFVTSLKLYETPNCFVEV
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
What are the official names of this protein?
6-carboxy-5,6,7,8-tetrahydropterin synthase, CPH4 synthase, Queuosine biosynthesis protein QueD.
What is the protein family that this protein belongs to?
Belongs to the PTPS family. QueD subfamily.
Protein: ATPL2_CERS1
Sequence: MTPETVQIASILGAAFAVGIGSLGPALGEGRAVAAAMEAIARQPEAAGTLSRTLFVGLAMIETMAIYCLVIALLLLFANPFTG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c 2, ATP synthase F(0) sector subunit c 2, F-type ATPase subunit c 2, F-ATPase subunit c 2, Lipid-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: U17LL_HUMAN
Sequence: MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 17-like protein 21.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP17 subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum.
Protein: MNMG_SULDN
Sequence: MNYDVIIIGGGHAGVEASLASARMGNKTLLISMLAENVGATSCNPAIGGLAKGHLVREIDALGGEMALITDEAGIQFRILNQTKGPAVRGSRAQIDMDRYRVIARNKILNTPNLELVQEMAESLIIEDGEVKGVKTNLLNEYSAKRVIVTSGTFLRGVIHVGEIKQIGGRYGEQSSDALSASLKSCGLEMGRLKTGTCARVDASTIDFSVMEEQGGDELPNPFSFRTNREEFRKTKKQIPCYITYTNQNTHDIIESNFYRAPMFTGQIEGRGPRYCPSIEDKINRFRDKERHHLFIEPQTLENTECYINGMSTSLPPDVQQLMINSVKGMENAKIVRYGYAIEYDFVDPRELKHTLETKKIKGLYLAGQINGTTGYEEAAAQGLMAGINASLSLQGKEPFILRRDEAYIGVLIDDLVTKGTKEPYRMFTSRAEYRLLLREESADTRLSHYGHTFGLIDDENYERVKAKEAQIQEGARILRETIFTPNKEFIAFLNSIGEEGVRDTISAEQIVARKSFDVSKMLKLIPEFEMYESYILDEILVEGKYARYVQKQSEEIQKMKKYLKVEIPQNFAFRSISGLSKEIVEKLESFNPPTLQAASQISGITPAAIEILHIYIKIDIKNRNK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_POLSJ
Sequence: MKVNPKNSPKDNLKDSPKVSARGKKVNKAWLHDHINDPYVKLAQKEGYRARAAYKLKEIDETLGLIKPGDCVVDLGSTPGAWSQYVRRKLSPTGAAAGELNGRIIGLDMLPMEPIEGVAFIQGDFREPEVLQKLEQALATDKGQVKVDLVISDMAPNLSGIESADAARIVHLVELAVEFAQNRMKPDGTLVVKLFHGSGYDELVKLFRATFKVVKPMKPKASRSNSSETFLVGKGLKKRAETVPELA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_PLAOC
Sequence: MAKGKDVRVRVILECINCVRNGVNKESPGVSRYITQKNRHNTPSRLELRKFCPYCFKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PDR8_YEAST
Sequence: MDGSHFPMKSTTGEPVSSGKKGKRRKVIKSCAFCRKRKLKCSQARPMCQQCVIRKLPQCVYTEEFNYPLSNTELFEQVPNVALVQKIENLQTLLKENDNNNAKPVYCRSSENPLRSLRTSVLGDNGSRYVFGPTSWKTLSLFEQNKFQTEFQNLWKVLKPLPECTKSQLNENDVVADLPSFPQMESCIKSFFAGPLFGILHIFNQDDILSLLDRLFIRDTTDKNLVILLDLQGNAKDKYNLGIVLQILCLGYYNQDIPSSVSHFLHTLSAASLSSSSSNFVEKLQFFLLSYISVMINCTDGVWDATQGVDLINELCQGCISLGLNDIDKWYLNESEETKQNLRCIWFWALFLDVSTSYDIGNPPSISDDLLDLSIFTAQNFQSPSIDFRRVKLMHDFLDVSRFTTREIHKREMNEKLTTFSLRLIEFIQSNFSPIEHYTNSVYYSDIDPFDILILSRSLSIVASIYNIEMIIAQQSRIIDKNRMVQFLLISISVCVNTMVFHFKEPINDQENVLTEGLKLSIILINPLLIRIVSQVYSLAFNRLIFREKAFLFLIDLDTGKKIQFIKYEEENFDELLTGFDVRTDKFLSFSGTIIRFYEIIDSIFAVNERNKRLLKAVSNFYQLTSTLAFERVSRVLFDKASQARIETEKIWLKKGINMEHFSDLMIEDFINDVWKTFKEISKDLWSIDKKKFYKQYHFDL
What is the function of this protein?
Up-regulates the transcription of the genes for ATP-binding cassette (ABC) transporters YOR1 and PDR15, for major facilitator superfamily transporter AZR1, for pleiotropic drug resistance SNG1, for alpha-glucosidase YJL216C and for YLL056C.
What are the official names of this protein?
Transcription factor PDR8, Pleiotropic drug resistance protein 8.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KLH40_XENTR
Sequence: MALPTQQADELRLYQQTLLQDGLKDMLDHDNFIDCVLKIQGKEFPCHRLVLAACSPYFRAMFLSNLEEGKKKEIDLEDVDPDVMGKILHYIYTSEIEITEKNVQDIFSVANMFQIPSIFTVCVSFLQKKLCLSNCLAIFRLGLLLDCPRLAVSARDFVCDRFHLIARDEEFYDLSPDELIAVISSDSLNIEKEEEVFEVVLKWALKEKEKRAKALPIIFESIRFRLIPQDYIKNKVEKHELVKSDKELLKKLQMVKDAQEGKLPAAVKKTPSKASEGKDGEGVVNGDLEEEEEALPGILNDTLRFGMFLKDMIFMISDTGAVAYDPSANECFFASLSAQIPKNHVSLATKENQLFVAGGLYYNEENKDDPLSSYFLQFDHLDSDWLGMPPVPSARCLFGLGESDNSIYLIGGKELKEGEQTLDTVLCYDRPSFKWGESDPLPYQVYGHTVVSHDNLVYVLGGKGNEKKCLKRVCVYNPKKFEWKDLAPMKTARSLFGSTVHKGKILIAAGVTDTGLTNTIEAYDVKTNKWEEFTEFPQERSSLSLVSMNGTLYAIGGFATTENESGEFVPTELNDIWRFNEEEKKWEGILREIRYASGATFVAARLNILRLTKM
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development.
What are the official names of this protein?
Kelch-like protein 40, Kelch repeat and BTB domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the KLHL40 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, myofibril, sarcomere, I band.
Protein: RS10_UREU1
Sequence: MNQELRIRLESYDHRLLDDTVKTIVDISNSTGSKLRGPIPLPTKKEIFTILRSPHVNKSSREQFERRTHKRLIILENPQPKTMEALKRLSVPFGVEVTFKI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: LPXD_PSEA6
Sequence: MNQTVSLQQLADKIGASLHLTDGDSGETQIHSLSTLASAGNGQISFLSNSRYRSQLEKTAAQAVILKSEDLSHCQCSALVMDNPYVGFALAAQLLDSTPRSADGISPLAVIADDVELGDNVSIGAHAVIESGVKLADNVQIGPGCFIGKEVSVGANTKLWANVTLYHRVVLGQDCLIQSATVIGADGFGYANDKGRWVKIPQLGTVILGDRVEVGASSTIDRGALDDTIIGNGVIIDNQCQVAHNVIIGENTAIAGCTVVAGSVTIGRNCTIGGMVAINGHMEICDNVYITGMSMVTKAIDKPGVYSSGMPAIENREWRKNAVALRNLSTLNQRVKTLEKSHLK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: PD2R2_HUMAN
Sequence: MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCRMRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRIMCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRRPGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVANPVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRPEEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS
What is the function of this protein?
Receptor for prostaglandin D2 (PGD2).  Coupled to the G(i)-protein.  Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization.  PI3K signaling is also implicated in mediating PTGDR2 effects.  PGD2 induced receptor internalization.  CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6.  Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
What are the official names of this protein?
Prostaglandin D2 receptor 2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, G-protein coupled receptor 44.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Internalized receptors colocalized with RAB11A.
Protein: TRUA_THESQ
Sequence: MKRVAAVIEYDGSNFFGYQGQPDVRTVQGVIEDALERIFKQRIYTQAAGRTDAGVHANGQLIAFNCPNDRMTTEDIKNAMNANLPDDVYVKEVFEVSKNFHPRFDVKKRIYHYFILTSKQKNVFLRKYVWWFPYELDLDAMRKAAKYLEGTHDFTSFKTGSDERDPVRTIYRIRILRLKNDLVLIRVEGRSFLRRMVRNIVAALVKVGLKQWEPEKMKEVLEARDRSAAAGTAPAHGLYFYKVLF
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: 3SAA_NAJNA
Sequence: LKCNKLVPLFYKTCPAGKDLCYKMYMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity (By similarity).  Has hemolytic activity towards human erythrocytes (EC(50)=0. 162 uM) and cytolytic activity towards various cell lines (PubMed:26456928).
What are the official names of this protein?
Cytotoxin 10, CTX10.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.