PharMolix/UniProtQA huggingface dataset:
Protein: GM_EHV1B
Sequence: MARRGAAVAEEPLLPSSGIVGIGPIEGINWRTWLVQVFCFALTTSVLFITLVTASLPQTGYPCFYGSLVDYTQKNHSVVDGVWMRQIAGGVAPTLFLETTSLVAFLYYTTLVLVAISFYLIISAVLVRRYARGKECTAVAGCTRPTTTLIASHVTLVLGTLATWLLQVVILLLSHKQAVLGAAVYVVHFVSLVFFCMSFSGLGTASAQYSSNLRILKTNLPALHKMAGPGRAVMTNLGMGMLGISLPILSLMLGIILANSFHITLWQTVTVAVGVFVALGLMFLIIVELIVSHYVHVLVGPALAVLVASSTLAVATHSYFVHFHAMVSVQAPNLATASKAIVGIMAVISIIMLVVRLVRAIMFHKKRNTEFYGRVKTVSSKARRYANKVRGPRRNPQPLNVAESRGMLLAEDSETDAEEPIYDVVSEEFETEYYDDPQRVPERSHRREYR
What is the function of this protein?
Envelope glycoprotein important for virion assembly and egress.  Plays a role in the correct incorporation of gH-gL into virion membrane.  Directs the glycoprotein N (gN) to the host trans-Golgi network.
What are the official names of this protein?
Envelope glycoprotein M, gM.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein M family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network. Host endosome membrane; Multi-pass membrane protein. Host nucleus inner membrane; Multi-pass membrane protein. Note=During virion morphogenesis, this protein accumulates in the trans-Golgi network where secondary envelopment occurs.
Protein: GDIR2_BOVIN
Sequence: MTEKAPEPHVEEDDDELDGKLNYKPPPQKSLKELQEMDKDDESLTKYKKTLLGDGPVVADPTAPNVTVTRLTLVCESAPGPITMDLTGDLEALKKETFVLKEGVEYRVKINFKVNKDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPIEEAPKGMLARGTYHNKSFFTDDDKHDHLTWEWNLSIKKDWTE
What is the function of this protein?
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.  Regulates reorganization of the actin cytoskeleton mediated by Rho family members.
What are the official names of this protein?
Rho GDP-dissociation inhibitor 2, Rho GDI 2, D4-GDP-dissociation inhibitor, D4-GDI, Ly-GDI, Rho-GDI beta.
What is the protein family that this protein belongs to?
Belongs to the Rho GDI family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CITD_YERE8
Sequence: MKIIREAVAGTLESSDVMVRIAPLNPPEIDLQIHSSVDKQFGDAIRYSVLALLEQYRVTGVQLIIDDKGALDCVLQARLETALLRASDEKILPWRAH
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_SPHAL
Sequence: MSTLPKTLTLDTSTSRANPTPQPMKRLTVPRIRQRKGGEPIVMLTAYTVRMAQLLDPHCDMLLVGDSLAQVIYGLPHTVGVTMEMMALHGAAVVRGSYHAAVIVDMPFGSYEGSPQQAFDNAARLLKETGAAAVKVEGGKVLAPTIEFLTQRGIPVMGHVGLTPQAVNILGGYGVRGKSEEEARSIVEDAVAVAQAGAFSIVIEGVLESIAIEITNKVACPTIGIGASAQCDGQVLVTDDMLGMFERVPKFVKRYRDMAGVVSGAVQDYADEVRSRSFPTEDQIYAG
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAC8_HALAS
Sequence: MKEDNNTSEESGRINRRNVLKTVGAAGLFAAGSTGMAAAADSLSQAEEPKLLTGTEKRTLARELAKTPAFRELAQRARADGAQIRSDADSIVAGYARGEDFAREVVQYDLENLTDAAEASIVIGRNPETGEIEVANLDYYYETDDGVLDEVHRFEPTNASETDGVQSAATSDGATVIAVDTDAIREAQNSEIDVDESSPSNAAPTPADIDITGCSACKYAAGQVCTIGCSAAGGFICGLLGITIPVAGLSCLGFVEIVCTVADEYSGCGDAVAKEACNRAGLC
What is the function of this protein?
Acts as an immunity protein for halocin-C8.  Able to block the halocin-C8 activity by sequestering the activity of halocin-C8 through specific and direct binding (PubMed:15978083, PubMed:18658263).
What are the official names of this protein?
Pre-protein-C8.
What are the subcellular locations of this protein?
[Halocin-C8]: Secreted. Note=Secreted (PubMed:15978083, PubMed:12811620). SUBCELLULAR LOCATION: [Immunity protein HalI]: Cell membrane. Note=Exclusively localizes to the cell membrane.
Protein: CH601_MYXXD
Sequence: MAAKEIFFHQSAREAILRGVRTLSDAVAVTLGPKGRNVVIEKSFGSPTITKDGVTVAKEIDLENKFENMGAQMVKEVASKTSDKAGDGTTTATVLARAIYEEGLKLVAAGHSPMDLKRGIDKAVEVVVGELKSLSKPTADKKAITQVGTISANGDETIGAIIADAMEKVGKEGVITVEEAKGLETTLDVVEGMQFDRGYVSPYFVTNRERMEAVLEDPYILISEKKVSSMQDMIPLLEQVARSGKPLIIIADDIEGEALATLVVNKIRGVLNVCAVKAPGFGDRRKEMLQDIAVLTGGTVVSEDLGHKFETLTLTDLGRAKRVTVDKDNTTVVDGVGTKAAIEGRIKLIRTQIDSVTSDYDREKLQERLAKLVGGVAVINVGAATETEMKEKKARVEDALHATRAAVEEGIVPGGGVAYLRALPALEKLKPGGEQDFGVAIIRRALQEPLRKIASNAGVEGAVVINKVREGTGAFGYNARTEVYEDLEKAGVIDPTKVERTALQNAASVASLLLTTEAMVAERPKGKAKGGGAGAGMPDYGGDDMDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNB_VIBCH
Sequence: MFQDNPLLAQLKQKIQETLPKKEGTIKASDKGFGFLEVDSKTSYFVPPPYMKKCMHGDKVVAFIRTENEREVAEPSELIEQSLTRFIGRVKLFKGKLNVAPDHPQLKKLSLKAKTKKGLNEADFQEGDWVVAHLVRHPLKGDDGFFVQISHKITDANDKIAPWWVTLAENDLPNSEPAGIDDWQLKDDADLVREDLTALPFVTIDGESTKDMDDALYAQQLPNGDFALTIAIADPTAYITPEDEMDKVARERGFTIYLPGRNIPMLPRDLADELCSLMENQVRPALCCSVTIRKDGVIGDDIRFFAANIKSHARLVYDHVSDWLETGSSEQWQPSEEIAQVVRDLYAFSQARANWRETHAVVFPDRPDYRFELSADNDVVAIHADMRRTANRLVEESMITANICAGKTLQTTFGFGVFNTHAGFKAEKMADVVELMAVNGAPNADAETLATVEGFAALRRWLATQETSYLDNRIRKYQSYSEIGNQPLPHFAMGLDVYATWTSPIRKYGDMINHRLLKAHILGKAPVQTPDETVGEELALHRKHHKIAERNVADWLYARTLADEPAKETRFQAEIFDINRPGMRVRLLENGAMAFIPGALILDNKERIECNGEDGTVLIDKEVVYKLGDVLEIVLTEVNQENRSLVGKPTQVFADLVSETQTSAEQPAEGAENNEPQV
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_RHOPS
Sequence: MPTINQLIANPRVVQKSRKKVPALQQSPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVIGYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHILRGVLDTQGVKNRKQRRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: YAJC_BUCAP
Sequence: MSFFIKDANAAVNQALEGNSYSLIFMLVTFILIFYFMLFRPQQKKDKEHKNLMNSIAPGDEVMTTSGFLGRVKKVTENGYVLLQLNNTTEIFIKKDFIVSSLPKGTLESL
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL33_CHLP8
Sequence: MAKGKENRIIVTLECTEAKKEGKPVSRYTTTKNKKNTTERLILKKYNPNLKRHTEHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: Y761_VIBPA
Sequence: MKKTTTLLGICAILSAPAFAAQLTLQKELVPRVINGEFVYPEWISDNNSIELKDGENQLAVTVGQIVFEDGKRRKFDSQPLLLEFDAEKDAELSLTYKTFRTIEEAKAFELDPKVVLKDKNGKEVDFSMVQLRKGGLQGFRDYEREVADYNNAVNKQATKSSIAQSPAVTKTLKESFNELSREEQQEFMQWAMRNLK
What are the official names of this protein?
UPF0319 protein VP0761.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: FTSA_BACSU
Sequence: MNNNELYVSLDIGTSNTKVIVGEMTDDSLNIIGVGNVPSEGLKKGSIVDIDETVHSIRKAFDQAERMVGFPLRKAIVGVNGNYINIQDTNGVVAVSSENKEIQVEDVRRVMEAAQVVSVPHEQLIVDVIPKQFIVDGRDEITDPKKMLGVRLEVEGTLITGSKTILHNLLRCVERAGIEITDICLQPLAAGSAALSKDEKNLGVALIDIGGGSTTIAVFQNGHLTSTRVIPLGGENITKDISIGLRTSTEEAERVKKQLGHAYYDEASEDEIFEVTVIGTNQKQTFTQQEAANIIEARVEEILEIVSEELRSMGITDLPGGFVLTGGQAAMPGVMSLAQDVLQNNVRVASPNYIGVRDPQYMTGVGLIQFACRNARIQGRKIGFKMPEEAIQEIAVSSSEEQEQHHHQNEVQQRPKGKQKTQAEHNKQSKMKKLLSMFWE
What is the function of this protein?
Cell division protein that is required for the assembly of the Z ring (PubMed:16159787).  May serve as a membrane anchor for the Z ring (By similarity).  Binds and hydrolyzes ATP (PubMed:11298280).  Also involved in sporulation (Probable).
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner (PubMed:11298280). In sporulating cells, preferentially localizes to only one of the two potential polar division sites (PubMed:11298280). Targeted to the membrane through a conserved C-terminal amphipathic helix (By similarity).
Protein: YO10_BPHC1
Sequence: MNKRKQKQISRILAAKRAEKCGQINAELQETGEYLEGRVHLLRAKLSINGINLKAYVLEQVINIKHQIVTERFGNVLLGLASGMIGGIIGMFMWVLCIL
What are the official names of this protein?
Uncharacterized 11.1 kDa protein in rep-hol intergenic region, ORF10.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: CPL1V_CRYNH
Sequence: MFSIPPSVRRLVFLFLIAAPLLSIVLPVAAAPAGVDPPSKLQPRAPQPSRRMGATKRSKKIEPLKKKDYSSFLCPGGSVACPIPGDEVSPSSVEALEKSLNSLADWFKVGFECVELETELNSCGGCLALGSGQDCALIENARTTGCENGSCQVYSCFDGYVVSPDRTSCVKRGSTIPATPVTAVNVEEFVADDQLPFGQ
What is the function of this protein?
Virulence factor which promotes fungal virulence by enhancing type 2 inflammation in the mouse host (PubMed:35896747).  Likely binds mouse Tlr4 independently of Ly96/Md2 and activates Tlr4 signaling to drive Stat3 phosphorylation in interstitial macrophages, which promotes the initial induction of Arg1/arginase-1 and increases macrophage sensitivity to Il4 signaling (PubMed:35896747).
What are the official names of this protein?
Protein CPL1.
Protein: MUTY_MYCTO
Sequence: MPHILPEPSVTGPRHISDTNLLAWYQRSHRDLPWREPGVSPWQILVSEFMLQQTPAARVLAIWPDWVRRWPTPSATATASTADVLRAWGKLGYPRRAKRLHECATVIARDHNDVVPDDIEILVTLPGVGSYTARAVACFAYRQRVPVVDTNVRRVVARAVHGRADAGAPSVPRDHADVLALLPHRETAPEFSVALMELGATVCTARTPRCGLCPLDWCAWRHAGYPPSDGPPRRGQAYTGTDRQVRGRLLDVLRAAEFPVTRAELDVAWLTDTAQRDRALESLLADALVTRTVDGRFALPGEGF
What is the function of this protein?
Adenine glycosylase active on G:A and C:A mispairs, as well as processing 7,8-dihydro-8-oxoguanine:A (8-oxoG) mismatches.
What are the official names of this protein?
Adenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: OR5M8_HUMAN
Sequence: MRRNCTLVTEFILLGLTSRRELQILLFTLFLAIYMVTVAGNLGMIVLIQANAWLHMPMYFFLSHLSFVDLCFSSNVTPKMLEIFLSEKKSISYPACLVQCYLFIALVHVEIYILAVMAFDRYMAICNPLLYGSRMSKSVCSFLITVPYVYGALTGLMETMWTYNLAFCGPNEINHFYCADPPLIKLACSDTYNKELSMFIVAGWNLSFSLFIICISYLYIFPAILKIRSTEGRQKAFSTCGSHLTAVTIFYATLFFMYLRPPSKESVEQGKMVAVFYTTVIPMLNLIIYSLRNKNVKEALIKELSMKIYFS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5M8, Olfactory receptor OR11-194.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERG24_BOVIN
Sequence: MAPPQGSRAPLEFGGPLGAAALMLLLPVTMFHLLLVARSGPARLLGPPPYLPGPEELWSPWALLLCLTWLGLQAALYLLPARKVAEGQELKDKSRLRYPTNGFQALVLTALLVGLGVSAGLPLSALPEMLLPLAFAATLTAFIFSLLLYLKALLAPASALAPGGNSGNLIYDFFLGRELNPRICSFDFKYFCELRPGLIGWVLINLALLIQEAELRGSPSLAMWLVNGFQLLYVGDALWYEEAVLTTMDIIHDGFGFMLAFGDLAWVPFTYSLQAQFLLYHPQPLGWPLASFICLINAVGYYIFRGANSQKNTFRKNPSDPRVADLETISTATGRRLLVSGWWGMVRHPNYLGDLIMALAWSLPCGVFHLLPYFYFLYFTALLVHREDRDERQCRQKYGLAWHEYCRRVPYRIVPYVY
What is the function of this protein?
Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis.
What are the official names of this protein?
Delta(14)-sterol reductase TM7SF2, Delta-14-SR, 3-beta-hydroxysterol Delta (14)-reductase, C-14 sterol reductase, Sterol C14-reductase, Transmembrane 7 superfamily member 2.
What is the protein family that this protein belongs to?
Belongs to the ERG4/ERG24 family.
What are the subcellular locations of this protein?
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TATB_MYCBO
Sequence: MFANIGWGEMLVLVMVGLVVLGPERLPGAIRWAASALRQARDYLSGVTSQLREDIGPEFDDLRGHLGELQKLRGMTPRAALTKHLLDGDDSLFTGDFDRPTPKKPDAAGSAGPDATEQIGAGPIPFDSDAT
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: VP11_MPRVN
Sequence: MALPAIHNWEPYEDSLIRIKHSCFAMHELYRERYLLARTRMMYYDVPIIVLSSVSSVFIAGGDAYMSKSMVQILTCIMSLCVGIIGSLKKFFRVDENREQCLETYKDLFRMFCELAIVMDMPSTSRPGDPQQYSTETSSKYAEIMQRSLVLEGQRTKYNPIYDDHNPLPPEKKKSILSRTRSTKLSSGEITPV
What are the official names of this protein?
Uncharacterized protein VP11.
Protein: GHRL_CAPHI
Sequence: MPAPRTICSLLLLSMLWMDLAMAGSSFLSPEHQKLQRKEPKKPSGRLKPRALEGQFDPDVGSQEEGAEDELEIRFNAPFNIGIKLSGAQSLQHGQTLGKFLQDILWEEAEETLADE
What is the function of this protein?
Obestatin may be the ligand for GPR39.  May have an appetite-reducing effect resulting in decreased food intake.  May reduce gastric emptying activity and jejunal motility (By similarity).
What are the official names of this protein?
Appetite-regulating hormone, Growth hormone secretagogue, Growth hormone-releasing peptide, Motilin-related peptide.
What is the protein family that this protein belongs to?
Belongs to the motilin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVB_ACIBS
Sequence: MQDRLISGTEKPEDHFDRAIRPTSLADYIGQPVVREQMEIFIGAARGRGEALDHTLIFGPPGLGKTTLANIIAREMGGNLKSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVAATTRAGLLTSPLRDRFGIVQRLEFYSVEDLTHIVSRSANLMDVPITVEGAEEVARRSRGTPRIANRLLRRVRDYAQVKGTGEVNHEMAQRALDMLNVDKAGLDTLDRRYLSMLLERFDGGPAGVEALAAAMAEDSGTLEDVIEPYLIQQGYVMRTARGRIATNQSYLQFGMTPPEPKN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: Y835_METJA
Sequence: MVDTSKIKALKEKSRRTVKSGSLKFILIILVVVIVGLLAFIAYNEISNLQFQEKITLENQKKAAIESINQMFAKYPNDPQKLIYINKIQMANNIEEINEVLEEAKKYISFKNYKIEAINQIKSMYGEYYSLSLSAQELVHKISLAQSTEEIENLLKSVDIEKDIRSIIEKQIDYVLASGDKYYYVEINGKSMFMTRDEILKYKKFWTLSELKSLKITPVSQLNKVAIEISAKQCGKLPHKGDIISIYSKDGSFITYGIIDSSYVILSSISYSESKSTSSNINELGESYSSSSSSSISYSLNNLPGILHATVIDRLDYDKIKKMFGEYGKKLNEIEDDTQIFDENVNYFLIISIPDDKIPDIIQIDPKDIVIVIKSKE
What are the official names of this protein?
Uncharacterized protein MJ0835.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MEF2A_MOUSE
Sequence: MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNEDSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLADSSMLSPPPATLHRNVSPGAPQRPPSTGSASGMLSTTDLTVPNGAGNSPVGNGFVNSRASPNLIGNTGANSLGKVMPTKSPPPPGGGSLGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNAQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFTSPGMLSLGQASAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNINIKSEPISPPRDRMTPSGFQQQQQQPQQQPPPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDTWVT
What is the function of this protein?
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes.  Also involved in the activation of numerous growth factor- and stress-induced genes.  Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival.  Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription.  In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation.  Associates with chromatin to the ZNF16 promoter (By similarity).
What are the official names of this protein?
Myocyte-specific enhancer factor 2A.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADA_HALSA
Sequence: MDTSSFETDLSLFKYDDLEALPDEYRELTPTARTERIEAARAELGDDVVVLGHNYQRREIVEHADFVGDSYQLSKEAANADADYVIFGGVTFMAESADIITDDSQSVILPSMEASCPMAGMAEALQVDAAWADITAAAPDETIIPITYMNSYADLKAFCAEQGGLVCTSSNAHRAFEWAFERGDKVLFLPDKHLGENTAHRLGMADATVEWDPWAAEGKTAEEVADADIVLWDGYCQVHERFTPEHVAEVRADHEDANVVVHPECRREVVEAADVVGSTATITETVADADPGETWAIGTEIHLANHLQRWHPEVNVVPLCGDACMDCNAMRQIDPNYLAWVLEELVEGRERNVIEVDSEEAELAQVGLDRMLEL
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_ZYMMO
Sequence: MLVIHTIAELRAHLDEHRQNRRKIGLVPTMGFLHQGHMALAQKAREESDVVVLSIFVNPIQFGVNEDLDVYPRDLPHDIALCKENGVDIIFAPSVAEIYPEPIMTSVEVQSLSNILIGRHRPNHFRGVTTIVAKLLNIVEPDKIIFGEKDYQQLIIVRRMIRDLSYKAEVIGVPIVREKDGLACSSRNARLTKEDRAAAVILSQSLKKAQKRILEGEKDVSTIRQLIEDDIKSEARAKIQSIDICHATKLDTLDRIDNQPIVILLAVAFGDVVLIDQQLVTPKEKAL
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_CHLPN
Sequence: MSLEDDVIAIIVEQLGVDPKEVNENSSFIEDLNADSLDLTELIMTLEEKFAFEISEEDAEKLRTVGDVFTYIKKRQAEQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IYD_DAPPU
Sequence: MENYVPFLVSHWRTVGLISVSIAAGVALGQLNQTHERAANKSQRVHTNSSIKAKQVKRESAIEQINEIEDDDEQSLEDQDVLPILFQYEKPSEADSIRRSEEFYRRMNQRRSVREISSDPVALEVIENIIKTGGTSPSGAHTEPWTFVVVSNLEMKQQIRQIIEAEEEINYKQRMGDVWVQDLQPVGTTWVKEYLTEAPWLILIFKQVHGFKRNGQKKIHYYNEISVSIATGFLLAAIQEAGLVTVTTTPLNCGPSIRVLLGRPVNEKLLLLLPVGYPKVGATVPDFKRKPLHDIMVHYQ
What is the function of this protein?
Catalyzes the dehalogenation of halotyrosines such as 3,5-diiodo-L-tyrosine (PubMed:24153409).  Likely to also catalyze the dehalogenation of other halotyrosines such as 3-bromo-L-tyrosine, 3-chloro-L-tyrosine and 3-iodo-L-tyrosine (By similarity).
What are the official names of this protein?
Iodotyrosine deiodinase, Halotyrosine dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TNR6_ENTFL
Sequence: MSEKRRDNRGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKLVATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNTETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFYIAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILILLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVEEAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNEDKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMKRLNKEKQQERLVA
What are the official names of this protein?
Transposase from transposon Tn916, Integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.