PharMolix/UniProtQA huggingface dataset:
Protein: GST2_YEAST
Sequence: MNGRGFLIYNGGEKMKQKMIIYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLRERPYVAGDSFSMADITVIAGLIFAAIVKLQVPEECEALRAWYKRMQQRPSVKKLLEIRSKSS
What are the official names of this protein?
Glutathione S-transferase 2, GST-II.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: FLGH_SULDN
Sequence: MIRNFLLFFMPIYAILFLSGCTANLSDPEIDFEPPAYVEEMPSKEDNKDFTSVGSVFGQGENPLFSDHKAMHVNDIVTVIISENTQSSNSGSKQISESDSLNLGGGAFTSAGTNSAVNSAVSKLNGIANLGFGSTSDSAYKGQGSATKDASFTTTVSARIVKVLQNGNYFISGKREILVDNQKQIIQIGGVIRPYDIDQGNRINSSQMSEAKILYKTQGDVERATDRGWGTKIIQSVWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: PANB_ERYLH
Sequence: MSTTFKLDTSTSRANPTPAPMKRLTVPKIRARKKDGKTEEPLVMLTAYTARQAQLLDAHCDLLLVGDSLGQVIYGLPSTIPVTLRMMADHAAAVVRGSYHSVVVVDMPFGSYEQSPQQAFESASFLLKESGAAAVKLEGGEAMAETVAFLNQRGIPVMGHVGLTPQAVNVLGGYAARGRNDAEADKIVTDAKALDDAGAFAIVIEGVLEPIAVAATEAVRAPTIGIGASAQCDGQVLVTEDMLGMFERVPRFVKKYGDIAETIEATAKTYAEEVRARSFPGPEQLYQPK
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2483_CAUVC
Sequence: MIPALDIDSLEHRLVAGDRAALARAITLVESRRADHQVAARTLLSRLMPLTGRAQRIGITGVPGAGKSTTIERFGCNLVEAGHRVAVLAVDPSSGRHGGSILGDKTRMEQLSVQANAFIRPSPSGGALGGVARKTREAMLLCEAAGFDVVIIETVGVGQSETVVADMVDIFLALLIPGGGDELQGIKKGLIELADLLVINKADADPAKAERSARDYRNALHILTPAHPDWTPPVLTASGLTGQGLDVLWTQILRHREVMTANGARAARRADQDARWMWAMVRDRLEDAFKTAPAVAALVPDLETAVREGEVPASAAADRLLAAFGL
What is the function of this protein?
May have GTPase activity.  May also bind and hydrolyze ATP.  May function as chaperone (By similarity).
What are the official names of this protein?
Putative GTPase CC_2483.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.
Protein: RL21_CHESB
Sequence: MFAVIKTGGKQYRVAANDTLLIERIAGEVGEIVQIGNVLAVGEGENVTIGAPFVEGASVAAEVVEQGRGPKVIAFKKRRRQNSRRKRGHRQLLTTVRIAEILLDGAKPSKKVAAKPATSEEKAAEEKPAKAKKEAAEKGASPRETKAAPLFSAPEGEPDNLTVIKGIGPVAAGQLKEQGLTTFAQLAALSDEDIARIDEAMPFSTDQIKDWREQAKEVAK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SYL_CERSK
Sequence: MSRYDPAATESRWQAAWDAAGVFTARHDPARPKYYVLEMFPYPSGRIHMGHVRNYTMGDVVARQKAAAGFSVLHPMGWDAFGMPAENAAMERGGHPKDWTYGNIADMRAQMKPLGLSIDWSREFATCDPEYYGQQQAMFIDMMEAGLVYRKNAVVNWDPVDMTVLANEQVIDGKGWRSGAPVVRRELTQWFFRISDYAGELLEALDTLKDWPEKVRLMQANWIGQSRGLQFAFSTAGAPEGFDRLEVYTTRPDTLMGASFAAISPDHPLARHLERHDAEVAEFVAECRRVGTSEEALEKAEKKGFDTGLRVRHPFDTAWELPVYIANFILMDYGTGAIFGCPAHDQRDFEFATKYGLPIRPVFLPEGTEETALAEAFVPMKSERVHYIRGFAGAEVQSGEEGVAAAIDFCESQGVGRGVTNYRLRDWGISRQRYWGCPIPVIHCETCGVVPEAKENLPVRLPDDVSFDVPGNPLDRHPTWRDCTCPKCGAKARRETDTMDTFVDSSWYYARFTAPRAATPTDAEEADYWMNVDQYIGGIEHAILHLLYSRFFARAMQKTGHLPAKAIEPFNALFTQGMVTHEIYLTRDAAGRPVYHLPEDVTDGKLADGTPVEIIPSAKMSKSKKNVVDPMNIIRQFGADTARWFVMSDSPPERDVEWTASGAEAASKHLHRVWRLADEISRADGEANAEDGALDKATARAIAEVTQGVEGFAFNKAIAKLYEFTNTLSRSGAGAEAKKRAMRTMAQLMSPMVPHLAEEVWAMLGGEGLVAQAAWPKADPALLIDDTVTLPIQVNGKRRGEITVPKEMAASEVEKLVLADEAVQRALGGAAPKKLIVVPGRIVNVVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_BACC3
Sequence: MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAKRPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSKEAAYFAEFQQMKMETPKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIAVAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEGGLAVAISESAIGANGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLTANVDEMRKAWKGAIPCLLK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSD_YERPE
Sequence: MSALKYCLLVTGPAYGTQQASSAYQFAQAVVGAGHHLVSIFFYREGVLNANQLTAPASDEFDLVRAWQQLAAEQAVTLNVCVAAALRRGITDQHEAEQLNLAAANLQPGFTLSGLGALAEATLTCDRMVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VTI12_ARATH
Sequence: MSDVFEGYERQYCELSTNLSRKCHSASVLSNGEEKKGKIAEIKSGIDEADVLIRKMDLEARSLQPSAKAVCLSKLREYKSDLNQLKKEFKRVSSADAKPSSREELMESGMADLHAVSADQRGRLAMSVERLDQSSDRIRESRRLMLETEEVGISIVQDLSQQRQTLLHAHNKLHGVDDAIDKSKKVLTAMSRRMTRNKWIITSVIVALVLAIILIISYKLSH
What is the function of this protein?
Together with either SYP41 or SYP61, required for membrane fusion; the fusion of phospholipid vesicles containing SYP41 or SYP61 and VTI12 is triggered by YKT61 and YKT62 (PubMed:15919093).  Functions as a v-SNARE responsible for the docking or fusion of transport vesicles within the trans-Golgi network (TGN) and mediates liposome fusion (PubMed:24021022, PubMed:15797025).  Necessary to deliver proteins to the protein storage vacuole (PSV) (PubMed:17360696).  May be also involved in retrograde traffic to the cis-Golgi (By similarity).
What are the official names of this protein?
Vesicle transport v-SNARE 12, AtVTI12, Protein ZIG SUPPRESSOR 1, Vesicle soluble NSF attachment protein receptor VTI1b, AtVTI1b, Vesicle transport v-SNARE protein VTI1b.
What is the protein family that this protein belongs to?
Belongs to the VTI1 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Prevacuolar compartment membrane; Single-pass type IV membrane protein. Cell membrane; Single-pass type IV membrane protein. Note=Accumulates in structural sterols-containing apical and subapical compartments of developing root hairs tips.
Protein: MURA_LACAC
Sequence: MKQMIIHGGKPLQGDVWIGGAKNSTVALIPASILSRTPVVLEGVPRIADVINLMDLLDEMDVRCEFKETTLRIDPTDIKMSPLPAGKIKSLRASYYFMGALLGRFGKAVVGFPGGDDIGPRPIDQHIKGFEALGASVKNENDQIIITAPEDGLHGAKIHLKMPSVGATMNIIMASVTAQGQTIIENAAKEPEIIDLATFLNNMGAVIRGAGTDVIRIEGVEMLKAQIPHTIIPDRIEAGTYVSLAACIGNGIRIHNIIEEHLDSYLAKVEEMGVVIDADEDSLYVYPAGDLKMVQVKTDVYPGFATDLQQPITPLLLTAKSGEGVVIDNIYPQRIGHIAQLQKMGANIKVADNIILAHPTEQLHGAEVIAGEIRAGACLMIAGLMAHGTTVIDKAGNILRGYDRIQEKLRQLGADVTIKDNPDVPGILDNI
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMDH_HALH5
Sequence: MWENKFQKEGLTFDDVLLVPAKSEVLPRDVSVKTKLTETLQLNIPIISAGMDTVTEAKMAIAIAREGGLGIIHKNMSVEEQAEQVDRVKRSESGVITNPFFLTPDRQVFDAEHLMGKYRISGVPIVDEDQKLVGILTNRDLRFIEDYSTLIDDVMTKENLVTAPVGTTLKEAEEILQKHKIEKLPLVDESGTLKGLITIKDIEKVIEFPNSAKDSQGRLIVGAAVGVSADTDVRVAALVEAGVDVIVIDTAHGHSKGVLEKVKAIREQYPDLTIIAGNVATAEATRDLIEAGANVVKVGIGPGSICTTRIVAGIGVPQITAVYDCANEARKHGVPIIADGGIKYSGDIVKALAAGGHAVMLGSLLAGVSESPGEREIFQGRQFKVYRGMGSLGAMEKGSKDRYFQENNQKLVPEGIEGRIPYKGPLHDTIHQLVGGIRAGMGYCGTKTIDELRENTQFIRITGAGLRESHPHDVQITKEAPNYTL
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: CLPC_STAAB
Sequence: MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHYTPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNTPTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVMSLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEYRKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASSKVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNTQNGMSTSLSEEDIAEVIAGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAESMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLTDTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELKEIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDGKEFKYDIAEQTSETKTPSQA
What is the function of this protein?
Required for growth at high temperatures, probably by acting as a chaperone during heat shock and targeting heat-denatured proteins for degradation by ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpC.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
Protein: PSID_PSICY
Sequence: MQVLPACQSSALKTLCPSPEAFRKLGWLPTSDEVYNEFIDDLTGRTCNEKYSSQVTLLKPIQDFKTFIENDPIVYQEFISMFEGIEQSPTNYHELCNMFNDIFRKAPLYGDLGPPVYMIMARIMNTQAGFSAFTKESLNFHFKKLFDTWGLFLSSKNSRNVLVADQFDDKHYGWFSERAKTAMMINYPGRTFEKVFICDEHVPYHGFTSYDDFFNRRFRDKDTDRPVVGGVTDTTLIGAACESLSYNVSHNVQSLDTLVIKGEAYSLKHLLHNDPFTPQFEHGSIIQGFLNVTAYHRWHSPVNGTIVKIVNVPGTYFAQAPYTIGSPIPDNDRDPPPYLKSLVYFSNIAARQIMFIEADNKDIGLIFLVFIGMTEISTCEATVCEGQHVNRGDDLGMFHFGGSSFALGLRKDSKAKILEKFAKPGTVIRINELVASVRK
What is the function of this protein?
L-tryptophan decarboxylase; part of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product (PubMed:28763571, PubMed:30283667).  The first step in the pathway is the decarboxylation of L-tryptophan to tryptamine by the decarboxylase psiD.  PsiD does not decarboxylate phenylalanine, tyrosine, or 5-hydroxy- L -tryptophan (5-HTP) (PubMed:30283667).  4-hydroxy-L-tryptophan is accepted as substrate by psiD as well.  The cytochrome P450 monooxygenase psiH then converts tryptamine to 4-hydroxytryptamine.  The kinase psiK catalyzes the 4-O-phosphorylation step by converting 4-hydroxytryptamine into norbaeocystin.  The methyltransferase psiM then catalyzes iterative methyl transfer to the amino group of norbaeocystin to yield psilocybin via a monomethylated intermediate, baeocystin.  4-hydroxy-6-methyl-l-tryptophancan also be converted the decarboxylase PsiD, kinase PsiK, and methyltransferase PsiM into respectively 6-methyl-norbaeocystin, 6-methylbaeocystin, and 6-methylpsilocybin (By similarity).
What are the official names of this protein?
L-tryptophan decarboxylase, Psilocybin biosynthesis decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family.
Protein: KLHL4_HUMAN
Sequence: MSVSGKKEFDVKQILRLRWRWFSHPFQGSTNTGSCLQQEGYEHRGTPVQGRLKSHSRDRNGLKKSNSPVHHNILAPVPGPAPAHQRAVQNLQQHNLIVHFQANEDTPKSVPEKNLFKEACEKRAQDLEMMADDNIEDSTARLDTQHSEDMNATRSEEQFHVINHAEQTLRKMENYLKEKQLCDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEAKQEEVRMEGVDPNALNSLVQYAYTGVLQLKEDTIESLLAAACLLQLTQVIDVCSNFLIKQLHPSNCLGIRSFGDAQGCTELLNVAHKYTMEHFIEVIKNQEFLLLPANEISKLLCSDDINVPDEETIFHALMQWVGHDVQNRQGELGMLLSYIRLPLLPPQLLADLETSSMFTGDLECQKLLMEAMKYHLLPERRSMMQSPRTKPRKSTVGALYAVGGMDAMKGTTTIEKYDLRTNSWLHIGTMNGRRLQFGVAVIDNKLYVVGGRDGLKTLNTVECFNPVGKIWTVMPPMSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPEGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATYNGFLYVVGGHDAPASNHCSRLSDCVERYDPKGDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQRNEWKEEVPVNIGRAGACVVVVKLP
What are the official names of this protein?
Kelch-like protein 4.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TKT1_CANAX
Sequence: MPSLDELTISTIRGLSVDAVSAANSGHPGAPLGLAPAAHVVWQKMKFNPKDPNWINRDRFVLSNGHACALLYSLLVLYKFELTVDDLKQFRQLGFKTPGHPEATDTAGVEVTTGPLGQGISNAVGIAIAQKQFAATYNKPDITLSDSYVYTFVGDGCLMEGVSSETSSLAGHLQLNNLIAFWDDNRISIDGDTAVSFTENVPDRYRAYGWNVLEVPDANTNIEAIAAAVDEAKKSTDKPTLIRLVTTIGYGSLKQGSHDVHGSPLKPDDIKQLKKSWGFKEDVDFFIPEEVSEYLAKHVSENQKVQKEWEAKLAEYKKKYPTEGAEIQRRLDGKLPEGWKEYLPKYTPADKPLATRKLSENVINALHGKIPEFIGGSADLTGSNLTRAEGSVDFQPPSTGLGNYDGVYIRYGVREHGMGAIMNGIAAFGANYKNYGGTFLNFVSYAAGALRLSALSHHPVIWVATHDSIGLGEDGPTHQPIETLAHFRAIPNLSVWRPADGNEVSAAYAAAIESTSHPSVIALTRQNLPQLEGSSIENALKGGYTLVKKDNPDVIIVSSGSEVSISVAASEELAKQGVKANVVSLPDFFTFDQQSDEYRLSVLPDGVPILSVEVMSTFGWSKYSHEQFGLNRFGASGKAADLYKYFEFTPEGIAERAQKTIKYYEGKQLLSPLDRAF
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase 1, TK 1.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: EFG1_SYNC1
Sequence: MTCPDLKNLRNIGIISHIDAGKTTVSERVLFYTGESHRIGEVHDGNAVMDWMEQEQERGITITATTTCCHWRDVRINLIDTPGHIDFTIEVERSLRVLDSAVVIFSAVEGVQAQTESVWRQADRYAVPRICLINKMDRIGADYRRVLEQMRKRFTTRPVLMHLPLGIEGDFAGVIDVLEGRCLTFSETDQGATVETCDIPEERQSEVAAAREQIVEAAADFDDAILADFLEGRPIKAARTRAALRRGVLTCRLCPVFLGSALRNKGIQPLLDAVIDYLPSPLQAPPIAASPPNHQDATAEPALLPCDPQGPLCALAFKVLSDAGRKLTYLRVYSGSLRAGDEILNSTQGVAEKVARLFRMHAHKRERVTEVQAGDIVAAVGLKHALTGDTLCRAEQPLRLEGLRIPEPVVSLAVEPRHIDDREKLPAALEKLLWEDPTFRVREDADTGQTILTGMGQLHLEIITDRLHREFGVEVRTGRPQVVYRETVQNSARHHERFHRETEGRIQSGEVTLEIAPSGRGKGLRIVLPEDENPLPARLREELKKCLHQSCAAGIRTGYPLTDVEITIIEAPFEPGLTTEIGLLAAAQRGLSLAATQAGLTLLEPVMALELTVPTEHAGQVIGSLQQKHGRIDGLETRSESELIQARAPLSQLFDYMGELRSVTRGRGTFAMEFSHYDPAPDEIQTLYGLL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIU_SALPA
Sequence: MEMDLNNRLTEDETLEQAYDIFLELAADNLDPADIILFNLQFEERGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADTEDGEINDIFARVLLCREKDHKLCHILWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: BNP_GLOBL
Sequence: MFVSRLAASGLLLLALMALSLDGKPVQQWSQGRPPGPPIPRLVVQQWSQGLPPGPPIPRLVVQQWSQGLPPGPPIPPLVVQQWSQGLPPRPKIPPLVVQQWSQGLPPRPKIPPLVVQKWDPPPVSPPLLLQPHESPAGGTTALREELSLGPEAASGPAAAGADGGRSGSKAPAALHRLSKSKGASATSASASRPMRDLRTDGKQARQNWARMVNPDHHAVGGCCCGGGGGGARRLKGLVKKGVAKGCFGLKLDRIGTMSGLGC
What is the function of this protein?
Exhibits hypotensive and vasodepressor activity.  Acts by activating natriuretic receptors (NPR1 and/or NPR2 and/or NPR3) (By similarity).
What are the official names of this protein?
Bradykinin-potentiating and C-type natriuretic peptides, Angiotensin-converting enzyme inhibitor, BPP-CNP homolog.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROFB_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NAIF1_MOUSE
Sequence: MAVPAKKRKMNFSEREVEIIVEELELKKHLLVNHFNAGVPLAAKSAAWHGILRRVNAVATCRRELPEVKKKWSDLKTEVRRKVAQVRAAVEGGEAPGPTEDDGAGGPGTGSGSGGSGTAIAPVLLTPMQQRICNLLGEATIISLPSTTEIHPVALGSTATTAAATVTLTQIPTETTYHTLEEGVVEYCTAEAPPPLPTEAPVEMIAQPPDTSVKPQALKSRIALNSAKLIQEQRVTNLHIKEIAQHLEQQNGLLQMIRRSQEVQACAQERQAQAMEGTQAALSVLIQVLRPMIKDFRRYLQNNTPNPAPASAPGPVAQNGQPDSIIQ
What is the function of this protein?
Induces apoptosis.
What are the official names of this protein?
Nuclear apoptosis-inducing factor 1.
What is the protein family that this protein belongs to?
Belongs to the NAIF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HOA_CUPPJ
Sequence: MPFNPGKKLYISDVTLRDGSHAIRHQYSIQNVKDIARALDKARVDSIEVAHGDGLQGSSFNYGFGAHTDLEWIEAVAGEISHAQIATLLLPGIGTIHDLDNAYKAGARIVRVATHCTEADVSRQHIERARELGMDTVGFLMMSHMTTPENLAVEAKKMESYGATTIYVVDSGGALSMDDVRARFRALKAVLDPSTTTGMHAHHNLSLGVANSIVAVEEGCDRIDASLAGMGAGAGNAPLEVFIAAADRMGWDHGTDLYTLMDAADDIVRPLQDRPVRVDRETLALGYAGVYSSFLRHSEVAANKYGIKTVDILVELGKRRMVGGQEDMIVDVALDLLNKA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: PKS5_RUBID
Sequence: MVTVDEVRKAQRAEGPATVLAIGTATPPNCIDQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPSMCEYMAPSLDARQDMVVVEIPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEIXAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGADPLPKIERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFKPLDITDWNSLFWIAHPGGPAILDQVETKLGLKPEKLEATRHILSEYGNMSSACVLFILDEVRRKSATNGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVGVTA
What is the function of this protein?
Polyketide synthase producing naringenin chalcone.  Can use p-coumaryl-CoA as substrate.
What are the official names of this protein?
Polyketide synthase 5, RiPKS5, Naringenin-chalcone synthase PKS5.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: ARGB_METST
Sequence: MVDQEQFDISNVLIEALPYIKKFHNKKIMIKYGGHAMIDENAMSSTARDTVLLKYVGMQPIVVHGGGPEISRSMDKMGKEPKFIGGLRVTDKETMEIVKMVLVGKINTEIVSKLGFHGGKSVGISGKDSYLVEASRKGLTKVKHENGEVLEVDLGYVGKIDRVNKQLVDDLTNNNYIPVISPLGIDDDGNTLNLNADTVAGSIASEVNAEKLIVLTDVPGILTDPDDPESMIRRIRTDELKELIKDGIITGGMIPKVETCINAVENGVKTAHILDGRLNHSILLEIFTKHGIGTMVRE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_HAMD5
Sequence: MELKELRKKSIEELEREILKLLREQFNLRMHAAASQLKETDLFKKIRRDIARIKTLLTEKVRVS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: U17LA_HUMAN
Sequence: MEDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKPPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYKPPLANYMLFREHSQTCHRHKGCMLCTMQAHITRALHIPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMRKACLPGHKQVDRHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHNSAKVLILVLKRFPDVTGNKIAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYSSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGVEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRRVEGTVPPDVLVIHQSKYKCRMKNHHPEQQSSLLNLSSTTPTDQESMNTGTLASLRGRTRRSKGKNKHSKRALLVCQ
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 17-like protein 10.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP17 subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum.
Protein: COT1_MOUSE
Sequence: MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQAGSGAPHTPQTPGQPGAPATPGTQGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS
What is the function of this protein?
Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription.  Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif.  Represses transcriptional activity of LHCG (By similarity).
What are the official names of this protein?
COUP transcription factor 1, COUP-TF1, COUP transcription factor I, COUP-TF I, Nuclear receptor subfamily 2 group F member 1, V-erbA-related protein 3, EAR-3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.