PharMolix/UniProtQA huggingface dataset:
Protein: Y2282_MYCTU
Sequence: MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRTPPAGAIRDLLSHITSRST
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator Rv2282c.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: SAHH_RHOPT
Sequence: MTAKFTDYIVKDIGLAEFGRKEISLAETEMPGLMATREEYGPKQPLKGAKIAGSLHMTIQTAVLIETLVALGAEVRWVSCNIYSTQDHAAAAIAAAGIPVFAVKGETLKDYWDYTAKLFDWSDGGTPNMILDDGGDATMFVHQGLRAENGDTMFLDQHNSEEEEIFFALIKRILKEKPKGYFATLAKNIKGVSEETTTGVHRLYDMEKAGKLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMLSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYQVVTMEDAAPIADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQVATLKNMKWDNIKPQVDEITFPDGKRMILLSEGRLVNLGNAMGHPSFVMSASFTNQTLAQIELFQNQGKYEKKVYVLPKSLDEKVARLHLAKIGVKLTELRKDQADYIGVKVEGPFKADHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_RHOJR
Sequence: MTIKLHHLRPAPGAKSDKIRVGRGEGGKRGKTAGRGTKGTKARKNVPAAFEGGQMPLHMRLPKLKGFTNPFRTEYQVVNVGDIARLFPEGGQVTVEDLVAKGAVRKNQLVKVLGDGDLTVAVQVTVDKFTGSAKEKIAAAGGTATEL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: IHFB_CHESB
Sequence: MIKSELVQTIANRNPHLFLRDVENIVNAIFDEITEALAQGNRVELRGFGAFSVKNRPARTGRNPRTGESVHVEEKWVPFFKTGKELRERLNADE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RF2_ROSDO
Sequence: MRADVQNTIEKIQKSLDLLAQRLDVETAPYRLEEFNARVEDPTLWDDPDAAQKLMRERQMLVDAMATHDSIKQEMADNIELIELGEMEDDADVVSDAENALRALEETAAKKELEALLDGEADSNDTFLEVNAGAGGTESCDWASMLARMYVRWAEKKGYKVELQSMSDGDEAGIKSATYKITGLNAYGWLKSESGVHRLVRISPFDSAAKRHTSFSSVWVYPVVDDNIDIEVNPADIRIDTYRSSGAGGQHVNTTDSAVRITHHPTGIVVTSSEKSQHQNRDIAMKALKSRLYQLELDRRNAAINEAHENKGDAGWGNQIRSYVLQPYQMVKDLRTNFETSDTKGVLDGDLDGFMAATLALDASGKTRAEAQNG
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_XYLFA
Sequence: MRVLILGSGVIGTTSAWYLSKAGCEVVVVDRQSGAGLETSYANGGQLSFGYTSPWAAPGVPLKAVRWLFERHAPLSIRPTTDWNQYVWLARMLRHCSAERYAVNKSRMLRLSEYSREALEALSAETGITFEGRHLGTIQLFRTQQQLDVVVRDIELLTQYGIPYEVLSPSQISKFEPGLADGSVRFPGALRLPHDQTGDCCLFTQRLAALAAKRGVEFRYGCTVQRLEVDGPRVTGAWINGALERADCCVVALGSYSPLLLAPLGLRLPVYPLKGFSLTLPMIDASRAPVSTVLDESYKVAVTRFDERIRVAGMAEVSGYDVSLNPRRRATLEMVVQDVYPGCGDLGRGEFWTGLRPATPDGTPVIGATPYQGLFLNTGHGTLGWTMSSGSGRYLADLICCRPCEISSEGLDMFRYLVSTIPCPQECAPCVPPTP
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: F120A_BOVIN
Sequence: MGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPHTPLRLLVDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACFGGNIELFVFFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHVKVAQSIEDHHQEVIGFCRENGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLASFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIQDTSDLDAIAKDVFQHSQSRTDDKVIRFKRAIGYYSATSKPMAFHPPHYLARPNPFGMPGIVPPYVPPQMLNIPQTSLQAKPVAPQVPSPGAPGQGPHPYNLAEPALTLETSGKNLTEQNYSNIPHEGKHTPLYERSSPINPAPSGSPNHVDSAYFPGSSTSSSSDNDEGSGGAANHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGNQIGTVQPIPCLLSMPTRNHMDITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEASKDLPPAALLYRPVRQYVYGVLFSLAESRKKTERLAFRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPASVPTHLTVLCCVLRYMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPVPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQAEQAAKVEKMRQSILEGLNFSRQSHPLPFPPPAALPFYPTSVYPRHFGPVPPAQGRGRGFAGVCGFGSPYGETVATGAYRAFRVATATGHCGAFSGSDSSRTSKSQGGIQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQGAIQGKPPYAASAEEVAKELKSRSGESKSSAMSSDGSLAENGVVAEEKPAPQMNGSAGDTRAPSHSESALNNDSKTCNTNPHLNALSTDSGCRRADALEAAVLKKEE
What is the function of this protein?
Critical component of the oxidative stress-induced survival signaling.  Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase.  Binds RNA and promotes the secretion of IGF-II.  May participate in mRNA transport in the cytoplasm (By similarity).
What are the official names of this protein?
Constitutive coactivator of PPAR-gamma-like protein 1, Oxidative stress-associated Src activator, Protein FAM120A.
What is the protein family that this protein belongs to?
Belongs to the constitutive coactivator of PPAR-gamma family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to plasma membrane upon ultraviolet exposure.
Protein: PYRD_NOVAD
Sequence: MTPYSLLRPLIFRIPAEPAHRLTIKALGLAQGGTTLAPTPSLAQRIAGLAFPNPVGMAPGFDKNAEVPDAMLGLGFGFVEVGTVTPRPQEGNPKPRLFRLVEDRAVINRMGFNNEGAQAVTNRLVRRRETGKHGLPGIVGVNIGANKDSADRIADYALMTRLMAPLASYLTVNISSPNTPGLRALQDEGALAALLDAVIEARGNMTTPVFLKLAPDLEPADIDSICRIAIEKQLAALIISNTTITRPVLRSAHAGEAGGLSGAPLRELALQRLRDFRKASGGAIPLVGVGGIATVDDAWERIRAGASLIQIYSAMVYEGPGLARRLVAGLERKVREAGLTSIAEAVGSE
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SKIPB_ORYSJ
Sequence: MVLRLPDPSHGGGAPPHDHTEDEWFKERYGGGGGGGDAPRSSRAVNPVPPYGRRSALAPRRKEDFGDGGAFPEVHVAQYPLDMGRRGGDGDGEQRGSSGGVLSLTVDGSGGRVEFDAVVRQGENAGKTVYSSPGDVLPKINAAAADADDDEQAAVEETTARTSAALRAIVEKRLSAVQPSNTLASNHDPEFIKYTPARQTSAFNSGAAERIIRMGETQQDPLEPPKFKHKRVPAPAGSPPVPVLRSPPRPPSQKDHDDWKVPPSISSWKNPKGYSIPLDKRAALDGRGLHDVQVSDAFAALAEALYAAEQKAREAVETRAKVHTEMKMREKEKAEQHLLQLATKARAEMLGAAPPAPSERSKAAAERDAIREERRRERRLEARAAAAAASKKSAATRDRDRDVSERIALGMANTGGGGGEVTYDQRLFNQEKGMGSGFAGDDQYNVYSGRLFAAQPALSTLYKPSKHGEEDPDAYGDADEHLGKIAKTRRFVPDKAFTGAPASVAAGKRERPVEFDGPEMEEDPFHLDQFLTQMKKGKHQ
What are the official names of this protein?
SNW/SKI-interacting protein B, OsSKIPb.
What is the protein family that this protein belongs to?
Belongs to the SNW family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MATP_YERP3
Sequence: MKYQQLENLESGWKWAYLVKKHREGEAITRHIENSAAQDAVEQLMKLENEPVKVQEWIDAHMNVNLATRMKQTIRARRKRHFNAEHQHTRKKSIDLEFLVWQRLAVLARRRGNTLSDTVVQLIEDAERKEKYASQMSSLKQDLKDILDKEV
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_DESVV
Sequence: MIVGIGIDITEIDRIAKGWGRFGDRFARRILHPHEVVRMPAANPVAFLAGRFAVKEAAVKALGTGFSDGIGPRDIEVGVAPAGAPQLVLHGKAAARMEALGATRTHVSLTHGRDTAAAVVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP73_PLAFA
Sequence: EFRETAGGVMTKLIERNTTIPTKKNQIFTTYADNQPGVLIQVYEGERAMTKDNNLLGKFQLEGIPPAPRSVPQIEVTFDIDANGILNVTALDKGTGKQNQITITNDKGRLSKDDIDRMVNDAEKYKEEDEQNKNRIEARNNLENYCYNVKNTLQDENLKTKIPKDDSEKCMKTVKSVLDWLEKNQTAETEEYNEKEKDTEF
What are the official names of this protein?
Heat shock 70 kDa protein PPF203.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SLBH_CROAT
Sequence: GFCCPSGWSSYDR
What is the function of this protein?
Activates platelets by binding to the platelet collagen receptor glycoprotein VI (GP6).
What are the official names of this protein?
Snaclec convulxin subunit beta homolog.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: XYLA_ECO55
Sequence: MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNSELGQQILKGQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPB_HYDS0
Sequence: MKKKELSIFDKDILKEASINSIKKLNPVELLRNPVMLSVEIGSTITTFDFFYDLATNNNHAWFSANVSLWLWLTVLFSNFAESIAESRGKARAKSLREAKSNLFAKKLKNKNDKTYEKIPASSLQKGDLFLLEKDDIIPIDGELIEGVLLVNESAVTGESAPVIRESGTDKSSVTAGTKVVSGSAVAVASVNPGETFIDKMISLVEGAKRRKTPNEIALEILIISLTIVFLVVVINFRALSYYSVYSTNKGSVVSLVVLVALFVCLAPTTIAALLPAIGIAGMDRLFKKNIIALSGRAIEAAGDANVLFLDKTGTITYGDRQAYKLIPVEGVSEEELAMVAHMASIGDTTAEGKSIYAFTKAKYNLSIDLKDYKVIEFDASTRISGVDTKNEHYRKGSSDAIEKYVSSFGGSIPKNLDKIVEEVAKEGGTPLVVAKDNRIYGVVYLKDIIKPGIKKKFRELRRAGIKTVMITGDNPLTAATIAAEAGVDDFLAQAKPEDKLRHIKKYQEEGYMVAMTGDGTNDAPALAQADVAVAMNSGTQAAKDAANIIDLDNDPSKLIEVVGIGKEILITRGAITTFSIANDISKYFVIVPAAVSKSYPELNILNILHLANPYIAILSAVIFNAIVIPMLIPLALKGVKYRPMDAQTLLVRNLSIYGIGGILFPFFGIWIVYWICEIFWRVL
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PCGF5_MOUSE
Sequence: MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELQRELEFWKKNKPQENGQDDISKVDKSKADEEGDENQDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENLCCLNCSASQVCSQDGTLYQSYPMVLQYRPRIDFG
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:27136092, PubMed:28596365).  Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity (By similarity).  Plays a redundant role with PCGF3 as part of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females (PubMed:28596365).
What are the official names of this protein?
Polycomb group RING finger protein 5, RING finger protein 159.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Note=Recruited by the non- coding RNA Xist to specific nuclear foci that probably correspond to the inactivated X chromosome.
Protein: TSAD_DINSH
Sequence: MTPSLTVLGIESSCDDTAAAVLRGPEVLSSVVYGQTALHAAFGGVVPELAARAHVEKLDIAVAAALSEAVLALDQIDVIAVTAGPGLIGGVLSGVMLAKGLSAASGVPLIGVNHLAGHALTPRFTDGLAFPYLMLLVSGGHCQFLRVEGPEAFHRLGGTIDDAPGEAFDKTAKLLGLPQPGGPAVEAEARAGDPARFVFPRPLLDRAGCDMSFSGLKTALLRARDGLVSAGGGLTAQDRADLCAGFQAAICDVLVEKSRRALTQSEGVTGFAVAGGVAANEQVRSGLARLAAELDAPFVAPPLRYCTDNAAMIAWAGQEAFSAGARSGLDLSARPRWPLDNSQPALLGSGKKGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOCD_YERP3
Sequence: MTDLTTSDSLQPAWQTRDHLDDPVIGELSNRFGPEAFVVQATRTGMPVVWVKREQLLEVMSFLRKQPKPYVMLFDLHGVDERLRTHRQGLPDADFSVFYHLLSIERNRDIMLKVALSEKDLHVSTATKIFPNANWYERETWEMFGITFDGHPHLTRIMMPQSWEGHPLRKDYPARATEFDPYVLTKQKEDLEMESLTFKPEDWGMKRGTENEDFMFLNLGPNHPSSHGAFRIVLQLDGEEIIDCVPDVGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIVVPDRVNTIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKVYDVIEAITGFRMHPAWFRIGGVAHDLPRGWERLLRDFLDWMPKRLDSYVKAALQNSILKGRSVGVAAYNAKEALEWGVTGAGLRATGVEFDVRKWRPYSGYENFDFEVPVGNNGDCYDRVMLKVEELRQSLRILEQCYKNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPSVIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SMBT2_MOUSE
Sequence: MERYLPVSKKRNSSSSLEKITGSANGNGTLYSEEDTNLEENDFSWGDYLEETGTRAVPHVSFRHVEISIRSNFQPGMKLEVANKNNPDTYWVATIITTCGQLLLLRYCGYGEDRRADFWCDVIIADLHPVGWCTQNNKVLRPPDAIKDKYSDWTDFLIRELTGSRTAPANLLEGPLRGKGPIDLITVDSLIELQDSQNPFQYWIVSVTENVGGRLRLRYVGLEHTESYDRWLFYLDYRLRPIGWCQENKYRMDPPSDLYYLKLPFEWKCALEKALVLAAESPLPMEVFKDHADLQSHFFTVGMRLETLHISDPFHIYPASVTKVFNSKFFQVAIDDLRPEADKPTMLCHADSLGILPVQWCLKNGVNLAPPKGYSGQDFNWVDYHKQRQAEEAPHFCFKNAFSRGFSKNMKLEAVNPVNPGEVCVATVVSVKGRLLWLHLEGLETPMPDIIVDMDSMDIFPVGWCEANSYPLTTPYKASSKSKRKTVHFKMEKQLLSPVPIEKIPHELCLLPPQMDSPVGAINAKYCCPQLFVNHRCFSGPFLNKGRISELPQSVGPGMCVLVLKEILTLITNAAYKPGRVLRELQLVEDPEWNSQEEILKAKYGGKTYRAVVKIVRTADQVMNFCRQVCAKLECCPNLLSPVLISETCPENCSVHTKTRYTYYYGKRRRVIQSSLRVSNIETPPKSTRRRKRRKSVYVQKRRKSAIVVPAGVPAGVPAGVPEDIPAGIPEGIPASIPESIPEGIPESLPEAIPESIPKGSAQKTEQEKRETLDTARKKTGYHGPAYQTDTSAAQVPFARPRRAVTLRRNSEALKRPPVERARRVRTVPTTASSNNRVKGPLVRIVKPEDSSQSDEEKLILESNPLEWSVTDVVRFIKLTDCAPLARIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERVKVAFYAQYAS
What is the function of this protein?
Transcriptional repressor of HOXB13 gene.
What are the official names of this protein?
Scm-like with four MBT domains protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: MYD88_RAT
Sequence: MSAGGPRVGSVSVDSYLFSLPLVALNVGVRRRLSLFLNPRTTAAADWTSLAEEMGFEYLEIREFETRPDPTRSLLDAWQGRSGSSVGRLLELLALLDREDILYELKDRIEEDCQKYIRNQQKQESEKPLQVARVESSVPQTKELGGITTLDDPLGQTPELFDAFICYCPSDIEFVQEMIRQLEQTDYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGVQQKRLIPIKYKAMKKDFPSILRFITICDYTNPCTKSWFWTRLAKALSLP
What is the function of this protein?
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.  Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.  Increases IL-8 transcription.  Involved in IL-18-mediated signaling pathway.  Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes.  Upon TLR8 activation by GU-rich single-stranded RNA (GU-rich RNA) derived from viruses, induces IL1B release through NLRP3 inflammasome activation (By similarity).  MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity).
What are the official names of this protein?
Myeloid differentiation primary response protein MyD88.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AAER_ECOL6
Sequence: MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK
What is the function of this protein?
Activates transcription of the aaeXAB operon.
What are the official names of this protein?
HTH-type transcriptional activator AaeR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: AMY_CAPAN
Sequence: FGNQQQLKSVADIVINHR
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: RL27_STRP7
Sequence: MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTGGSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SYR_MAGMM
Sequence: MRQSIEELMEHAQNTLLAEGVIPADAKLGGIKVERPKDKSHGDFSINTAMVLAKQARMKPRDLAQRLVDALPSGQGVVSRCEIAGPGFINFFVTPERLRGVVADVLQRGGSYGQGNVGAGQKVLVEFVSANPTGPMHVGHGRGAVTGDVLARILECAGYAVQREYYLNDAGVQVQVLGRSVMLRYRQLFGDAVEVAEGCYPGDYVVDIARALKEKDQDKWLEVARAEPDEYPREMLEFAMQQVLTWIKADLARLNIRFDHWFSEFSLHSEGRIEHALEVLSQKGCLYEGVLEPPKGKKSEAWASRPQLLFKATDFGDEVDRALRKSDGSYTYFAADVAYHLNKAERGFERLVNIWGADHGGYVRRVQAALGALTGKQNLLDVVLIQMVNLTRGGEPVKMSKRAGTFVTLEEVVEATSSDAVRFWFLSRGSGAQLDFDLDLAVAKNNDNPVYYVQYAHARICSIWDKAQHEGVALQAQGWSGVDLSPLGEGAEWDLIRKLDLFPDVVEGAAVHQEPHRIPYYLLDLAAAFHTFYNSHRIMDVDAGTRDARLVLILAVKQVIANGLELLGVQQPRSM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YH74_ARCFU
Sequence: MVSEKVLAIIAVALGTYLARFLPLKIKFATSDKIKSFLSLSSTSVISALFVTSVFTPDAAEFGVRVAALFPLILSFYRWRNFGLSIFAAVLSYYLLRLAV
What are the official names of this protein?
Uncharacterized protein AF_1754.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1155.1.
Protein: Y1052_STRGC
Sequence: MNKNYSYPLDLSWSTEELASVLSFLNDVEKAYESKVSAQQLLGSYAVFKEVVPSKAEEKRIGREFESVSGYSLYRAVQAAKNTEKGMISLGK
What are the official names of this protein?
UPF0223 protein SGO_1052.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: RTKN2_DANRE
Sequence: MDPPRDIQHFKRNIASRSTVSSCSSLAMEIKRKKIRESMFFPSEDCDIKEKMEFEMRMRAGAYKLMVASTKKEQVLDASRSLLTCNARIKAYMSEAQKRTGHQDFRRPSDSQGQVPCKGKVAISGLRIPLFWKDSEHFNSKGNTQRVAVFCLMKIGSEIFDTEMVIADSSMTDICFEGVKIFSEVKPDFELTFELYICGLDEEATFANTPKKLARKLRSSFGRSSGRKLCPLLDGGDPDTFLQSNPIPPGARYSLLAYTTLGLEQAEGSFQSHSLIILQNVEASSWLPLYGNLCCQLVAQPDCMTLDMMSGFLSQQQSIEGLQRRCRLYCVLKAGKISCYYSPEEIQAKVEPILIIPINKETRIRVVENDHQRPGSRLNLINPGNGDSASHVFIAESPDVLQEWLDSLWQHIYDQSQWQHTCDKLMEIDVLSPRKPPLFLTKQADSVYNDLSIGSPGKFESLTDIIHNKIEETNGRFLIGQEEETEPPHWAALFEGSRPIVVQKTVLSPGKESNRSITSPDTGSKKKRRAPPPPPDKLPFTSVSTNQEKENCKGPKPRAGRPSLDAKFSAIIQQLQKSHTSTRKNAPLGQIETGQQPEKRAEESDLPEYTKKEYIVDPQPPVPAPRNKLRMSFREKMNPKAW
What are the official names of this protein?
Rhotekin-2, Pleckstrin homology domain-containing family K member 1, PH domain-containing family K member 1.
Protein: YHIT_HELPY
Sequence: MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSGDKH
What are the official names of this protein?
Uncharacterized HIT-like protein HP_0404.
Protein: F16A2_CERS5
Sequence: MTIELEDLGLTPELADVMQRLARVGGQIARLISRNGLETDLAAGVGTNAGGDGQKALDVIADNAFRAALAGSAVAHYASEEQDEVVTLGEGALALAIDPLDGSSNIDVNVSIGTIFSIFPAAESPEASFLRLGTEQIAAGYIIYGPQCALVCSFGRGVHHWVLDLDAGIFRRMADIRPLPAETSEFAINASNYRHWPKPVRAFIDDLMAGADGPRGKNFNMRWIASLVAETHRILMRGGVFLYPGDDRKGYERGRLRHVYECAPIAFLITQAGGGASDGCDPILTALPDRLHARTPFVFGCAGKVACVAAYHDLPGQETSALFGTRGLFRS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 2, FBPase class 1 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOOK3_BOVIN
Sequence: VELQNRLSDESQ
What is the function of this protein?
(Microbial infection) Serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking.
What are the official names of this protein?
Protein Hook homolog 3.
What is the protein family that this protein belongs to?
Belongs to the hook family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Golgi apparatus. Note=Enriched at the cis-face of the Golgi complex. Localizes to microtubule asters in prophase (By similarity). Localizes to the manchette in elongating spermatids (By similarity).