PharMolix/UniProtQA huggingface dataset:
Protein: SYS_RHOPA
Sequence: MHDIKAIRDNPQAFDAAFTRRGLAPIAGSLMKLDEVRRAAVQAAEQAQARRNAASKEIGDAKKAKDNARAEALMAEVTELKTTMPALDAAVKEADEALKKALSEIPNLPLPEVPEGADEHGNVEHHRFGEKPSYSFTPKPHYDLGEALGMMDFEAAAKLSGARFTVLKKGLARLERAIGQFFLDVHTGDHGYTEVNPPLLVKDDAMFGTAQLPKFREDQFAAGAIGSGGEGYWLIPTAEVSLTNLVRESILDEKELPMRLTALTPCFRAEAGAAGRDTRGMIRQHQFTKVELVSITTPEQSKDEHERMLSCAEEVLRRLGLHYRVMTLCTGDMGFASQKTYDIEVWMPGQGEGGAYREISSCSVCGDFQARRMDARSRGSDGKPRFVHTLNGSGTAVGRALIAVIENYQQEDGSIAVPDVLQPYMGGLKVIAKA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_ANAMM
Sequence: MEIVAENRKARFDYFVLQEYDAGMVLVGSEVKSLRQRKVNMGDAYVLEKDMELWIHNLHISEYNRADRKNHKPLRVRKLLLRKREIHKIAGNIKVSGLAVVPLMIFFNNKGIAKIKIAIVKGKKLYDKREAIKTRDWQREKSRISRREV
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: NUOH_ECO5E
Sequence: MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVPVSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARGE_SALAR
Sequence: MKNVLPPFIEIYRALIATPSISATEASLDQSNASLITLLAGWFSDLGFNVEVQPVPGTRNKFNMLASSGHGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRAVDVTQLKKPLYILATADEETSMAGARYFSETTALRPDCAIIGEPTSLQPIRAHKGHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQLRDSLKARYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLNDALAPVSERWPGRLTVAELHPPIPGYECPPDHQLVEVVEKLLGTKTDVVNYCTEAPFMQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVVHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADT2_HUMAN
Sequence: MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).  In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (By similarity).  Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis (By similarity).  Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A5/ANT2 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity) (By similarity).  Proton transporter activity requires free fatty acids as cofactor, but does not transport it (By similarity).  Probably mediates mitochondrial uncoupling in tissues that do not express UCP1 (By similarity).  Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1. 5 kDa, and which contributes to cell death (PubMed:31883789).  It is however unclear if SLC25A5/ANT2 constitutes a pore-forming component of mPTP or regulates it (By similarity).  Acts as a regulator of mitophagy independently of ADP:ATP antiporter activity: promotes mitophagy via interaction with TIMM44, leading to inhibit the presequence translocase TIMM23, thereby promoting stabilization of PINK1 (By similarity).  As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (PubMed:20797633).
What are the official names of this protein?
ADP/ATP translocase 2, ADP,ATP carrier protein 2, ADP,ATP carrier protein, fibroblast isoform, Adenine nucleotide translocator 2, ANT 2, Solute carrier family 25 member 5.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: NADK_PSEA8
Sequence: MEPFRNIGIIGRLGSTQVLDTIRRLKKFLIDRHLHVILEDTIAEVLPGHGLQTCSRKIMGEICDLVVVVGGDGSMLGAARALARHKVPVLGINRGSLGFLTDIRPDELEAKVGEVLDGQYIVESRFLLDAQVRRGIDSMGQGDALNDVVLHPGKSTRMIEFELYIDGQFVCSQKADGLIVATPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHMLSSRPIVVDGNSELKIVVSPNMQIYPQVSCDGQNHFTCAPGDTVTISKKPQKLRLIHPIDHNYYEICRTKLGWGSRLGGGD
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_AROAE
Sequence: MFQGAIALSLDAKGRLAIPARHRDALVPDGAPLVITAHPHKCLLVYPLSAWEPIRDRIAAMPGFDPRTSAFKRLLVGFAQEEGLDAAGRVLLAGSLRQWAQLEKQVWLVGQGAHFELWSDAGWQAQQEAMLALTGDALPPGFESLAL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS6_ALIF1
Sequence: MRHYEIVFMVHPDQSEQVAGMIERYTGSITEAGGTIHRLEDWGRRQMAYPINKLHKAHYVLMNVESEQAVIDELETAFRYNDAVLRNMIMRTKAAITEPSVMMKAKEERSAKREDAAPRAEEAAAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: SCX4_CENSC
Sequence: KEGYMVNKSTGCSYSCPKTGESVYCDKECKAKNQGGSYGFCQYSNCWCEGLPESTPTWPLDDKPCD
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin CsEv4, CsE v4, Neurotoxin 4.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL_PINED
Sequence: MSPKTETKASVGFKAGVKDYRLTYYTPEYQTKDTDILAAFRVTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEENQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAINKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVMPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEVIREASKWSPELAAACEIWKEIKFEFDVIDRL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CDH_ECO81
Sequence: MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEQCLPNQQENQNPSPCAEVKPNAGYVVLKDRHGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSQKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLANISSRWLPMPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQCEILR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FLGB_AGRFC
Sequence: MEKSMQPIQLFELASRQAEWLSVRQEVVATNIANANTPKFHAKDVSPFEAVMQATSQQVGMARTNPAHLGESTLSENIAVRDNPVNNEIGMQESGNSVGLAEEMTKTGEIKRQYDLNASLVKSFHRMMLMTVKR
What is the function of this protein?
Structural component of flagellum, the bacterial motility apparatus.  Part of the rod structure of flagellar basal body (By similarity).
What are the official names of this protein?
Flagellar basal body rod protein FlgB.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: MALX4_YEAST
Sequence: MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQLSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE
What is the function of this protein?
Alpha-glucosidase with broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides.  Not required for isomaltose utilization, but overexpression allows the IMA1 null mutant to grow on isomaltose.
What are the official names of this protein?
Oligo-1,6-glucosidase IMA4, Alpha-glucosidase, Flocculent-specific protein 2, Isomaltase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: GPPA_VIBPA
Sequence: MSQAGSSPLYAAIDLGSNSFHMLVVRHIDGSVQTMAKIKRKVRLAAGLDEHNSLSMEAMQRGWDCLSLFAERLQDIPTQNIRIVGTATLRTATNVDVFLEKANQILGQPIEVISGEEEAATIYKGVAHTSGGSGRRLVVDIGGASTELIIGEGFEAKALTSLKMGCVTWLENFFKDRQLNARNFEAAIEGAKQTIKPILEQYTDLGWDVCVGASGTVQALQEIMLAQGMDEVITHSKLKRLQKQAMLADHLEELDIEGLTLERALVFPSGLSILIAIFELLEIDAMTLAGGALREGLVYEMVDELRQNDIRARTICSVQSRYQLDCQYGEQVATLAGKLLEQAGGDEWIAEPQGKVLLETTAKLHEIGLTIDFKKGGEHSAYLLQNLDLPGYTRAQKFFIGEIARRYREQLSSLPEQHAISGTSAKRVLRLLRLAVLLTHRRNPSLEPQVELLAEGDKLTLSIDAKWLEANPLTAAELEIESNRQTDIGWPLTITAC
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: S2538_YEAST
Sequence: MTEQATKPRNSSHLIGGFFGGLTSAVALQPLDLLKTRIQQDKKATLWKNLKEIDSPLQLWRGTLPSALRTSIGSALYLSCLNLMRSSLAKRRNAVPSLTNDSNIVYNKSSSLPRLTMYENLLTGAFARGLVGYITMPITVIKVRYESTLYNYSSLKEAITHIYTKEGLFGFFRGFGATCLRDAPYAGLYVLLYEKSKQLLPMVLPSRFIHYNPEGGFTTYTSTTVNTTSAVLSASLATTVTAPFDTIKTRMQLEPSKFTNSFNTFTSIVKNENVLKLFSGLSMRLARKAFSAGIAWGIYEELVKRFM
What is the function of this protein?
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix.  Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial glycine transporter, Heme biosynthesis protein of SLC25 family, Solute carrier family 25 member 38 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MIAA_ECO57
Sequence: MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLGGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PA2B3_BUNFA
Sequence: AVCVSLLGAANIPPQPLNLLQFKNMIQCAGSRLWVAYVKYGCYCGPGGTGTPLDQLDRCCQTHDHCYDNAKKFGNCIPYFKTYEYTCNKPDITCTDAKGSCGRTVCDCDRAAAICFAAAPYNLANFGIDKEKHCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that has only a weak enzymatic activity.  Inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 Vb-2, svPLA2, Phosphatidylcholine 2-acylhydrolase, Toxin V-3.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ASSY_CHRSD
Sequence: MSDVKKVVLAYSGGLDTSVIVKWLQETYDCEVVTFTADIGQGEEVEPARAKAQALGVKEIYIEDLREEFVRDYVYPMFRANTIYEGEYLLGTSIARPLIAKRLVEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLNSREKLMNYCEEHDIPVDFSTSKKKSPYSMDANLLHISYEGGILEDPWAEAEEDMWRWSVSPEAAPEQPTYVELTFDKGDIVAIDGEPLKPHEVLSRLNRMGGDNGIGRLDIVENRYVGMKSRGCYETPGGTIMLRAHRAIESLTLDREAAHLKDELMPKYAEVIYNGYWWSPERKMLQAAIDATQDNVNGVVRMKLYKGSATVVGRKSEQSLFDASIATFEDDAGAYDQKDAEGFIKLNALRLRIAAGKGRQAD
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_MICTM
Sequence: MSNQHALLISNLLPVGSNISTWWNFGSMLLTCLMLQVLTGFFLAIHYTANINLAFSSVVHITRDVPCGWIMQNTHAIGASLFFICIYIHIARGLYYGLYLNKNVWLSGVTLLMTLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGVAVTTWLWGGFSINDPTLTRFCALHFILPFIIISLSSIHIILLHNEGSNNPLGTNSDIDKIPFHPYHSYKDFMTTTSMIILLPISLSVSPDLLXDPEKLTKPNPXXXXXXXXXXXXXXXXYGLLRSIPNKLGGTLALLMSILILTLPPFTHTSYIRPMTFRPLSQTLFWTLIATFVMITWTATKPVEPPFITISQLTSIFYFSFFIMNPLLSWTEHKIMMQS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COFH_METJA
Sequence: MDPNKFREKEISKKEALELFEDNEIIFELFKFADSLRREEVGDIVTYVVNRNINFTNICVGNCRFCAFRANENDKHAYFLDIDEIAKRAVEAKKFGCTEVCIQGGLHPKIDTYYQAEILKAVHEATKPYGDIHIHAFSPMEVYFGAENAGLDIKEALKILKENGLNSMPGTAAEILDDDIRAELCPNKIKTKEWIYIIKEAHKLGIPTTATMMYGHIEEYKHWVNHLFIIKEIQEETNGFTEFVPLSFMHKYAPIYKEGKAKAGATGIEDLKVFAVSRIIFKGLIKNIQASWVKLGKKMVQVALRCGANDVGGTLIEESISRSAGAEHGVYMSVEEIRDMIKRVGLIPKERTTLYKILE
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: SYA_MYCPA
Sequence: MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLGARTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKREAIELAWTLLTGSVEQGGYGLDPERIWTTVYFDDDEAVRLWQEIAGLPAERIQRRGMEDNYWSMGIPGPCGPSSEIYYDRGEEFGVGGGPIANEDRYVELWNLVFMQSERGEGTSKTDFEILGPLPRKNIDTGMGVERVAFVLQGVHNVYETDLLRPVIDAVAARAPRPYDAGNHDDDVRYRIIADHSRTAAILIGDGVTPGNDGRGYVLRRLLRRVIRSARLLDIEGPIVGDLMATVRDAMGPSYPELVTDFDRIARIAVAEETAFNRTLAAGSKLFDEVASTTKATGAKSISGSDAFTLHDTYGFPIELTLEMASEAGLQVDEVGFRELMAEQRRRAKADAAARKHAHADLTAYRELVDAGPTEFTGFDELSSEARILGIFVDGKRVPVVTHGGDGADRVELVLDRTPLYAESGGQIADEGTISGTGAGESARAAVTDVQKIAKTLWVHRVNVESGEFVEGDTVIAAVDPQWRRGATQGHSGTHMVHAALRQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTEEQRTQIEEVTNQAVQADFEVHTFTEQLEKAKAMGAIALFGESYPEQVRVVEIGGPFSLELCGGTHVHNSAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKVPSEEVPARVANLVERLRAAEKELERMRLASARAAAGNAAAGAERIGNVRVVAQRMSGGMTAADLRSLVGDIRGKLGSDPAVVALIAEGEGGSVPYAVAANPAAQDLGIRANDLVKQLAAPVDGRGGGKADLAQGSGKDPAGIDAALDAVRSEIAAIARVG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAF1_IPOBA
Sequence: MRLVVVGLWCLILGLILNPTKFCDAGVTSSYVRKSLSALPNAEDVDMPWDSDVFAVPSGYNAPQQVHITQGDYEGRGVIISWTTPYDKAGANKVVYWSENSKSQKRAMGTVVTYKYYNYTSAFIHHCTIKDLEYDTKYYYRLGFGDAKRQFWFVTPPKPGPDVPYVFGLIGDIGQTHDSNTTLTHYEQNSAKGQAVLFMGDLSYSNRWPNHDNNRWDTWGRFSERSVAYQPWIWTAGNHEIDYAPDIGEYQPFVPFTNRYPTPHEASGSGDPLWYAIKRASAHIIVLSSYSGFVKYSPQYKWFTSELEKVNRSETPWLIVLVHAPLYNSYEAHYMEGEAMRAIFEPYFVYYKVDIVFSGHVHSYERSERVSNVAYNIVNAKCTPVSDESAPVYITIGDGGNSEGLASEMTQPQPSYSAFREASFGHGIFDIKNRTHAHFSWHRNQDGASVEADSLWLLNRYWASEDASSMSAM
What are the official names of this protein?
Purple acid phosphatase 1, Manganese(II) purple acid phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR5_MACCJ
Sequence: MAESYKQSGVDIHAGYEAVERMKKHVNKTMRKEVLGGLGSFGAAFDLSQLNMKAPVLVSGTDGVGTKLRLAIDSDRHDTIGIDAVAMCVNDILTTGAMPLYFLDYLALNKVDPVIVEQIVKGVADGCAESECALIGGETAEMGDMYHTGDYDIAGFAVGAVEKDAYITGERIAEGDVILGLASSGIHSNGYSLVRKIIKDNNLDLDAEFDNGKTLLDVVLEPTRLYVKSAKAILDAADVHGMCHVTGGGFIENVPRVFVTDGLYPEIDVTNIPRQKIFDLLQEKGSIDKMEMYNIFNMGIGFIFIVPREAVEKVRSAVNEEVFEIGRVVRGDKAIDIKGV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XGPT_VIBCM
Sequence: MSKKFVITWDNMQHYCRELAQRQMPAEQWKGILGVSRGGLVPAAILARELGIRYVDTVCISSYDHDHQRDMTVLKAPEHDGEGFLIIDDLVDSGDTARKIREMYPKAKFVTVCAKPAGKDLVDEYVVDIPQDTWIEQPWDMVLSYVEPVNRKQK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.