PharMolix/UniProtQA huggingface dataset:
Protein: ATPF_KOCRD
Sequence: MLAAEEANPLIPDVWEMLITGIGFVILLFIAIKYIVPAFEKVFKDRADAIEGGLAKAKAAQAEAKAARDEYNQQLESARLEAQKIREEARSEGEKILADFKDRANMESARITENAHKAIEAERAAAVVSLRDEVGTLATQLASKIVGESLNDDDRANRVVDRFLADLDAEQGRTGAAR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HEM1_SHISS
Sequence: MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQILADEVGAEVIALSEIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMAWLRAQSASETIREYRSQAEHVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAPTKSLQQAARDGDNERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: MOAA_PETMO
Sequence: MIDKYGRSIDYLRVSITDRCNLRCIYCMPPQGVTFKTHSSILRYEEIIKIVEVGTELGIKKVRITGGEPLVRQGVVNLIKELRKIPELEDITMTTNGVLLPKYAFALKRAGLSRVNISLDSLNPDTYKTITRRGEFSQAIEGIKAALEVGLNPVKINTVVMKGINDNELENFVNLTIDKDLHVRFIEYMPMGETSLLSGNYYVSLNEFKEIIIDKMGMVPVNIQNNGPSKDFKVPGAKGTVGFITAISHNFCSTCNRMRLTADGFLRPCLASDVEVNMRDEDGKISSEGVREKFEKALLLKPISHNFYKNDFFPKKNMSQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: SFSA_ECOHS
Sequence: MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGCATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICVNTLWANRLTKEAILNESISELSGYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKHLRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAEISAEGMALKKSLPVTL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: AAMAT_AMABI
Sequence: MSDINATRLPIWGIGCNPCVGDDVTTLLTRGEALC
What is the function of this protein?
Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters (PubMed:18025465, PubMed:7642577, PubMed:8702941).
What are the official names of this protein?
Alpha-amanitin proprotein.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: MOTA_HELPJ
Sequence: MDLSTILGLVLAVASISLGDILEDGNPLHIIHLSSVIIIVPTSLFAAMTGTHARYVKAAYKEIKIVFLNPKINLNETIKNLVELATLARKDGVLSLEGRVAQIEDDFTRNGLSMIIDGKDLKSVKESLEISIEEMEEYYHGAAHYWETAGETAPTMGLVGAVMGLMLALQKLDNPAEMAAGIAGAFTATVTGIMCSYAIFGPFGHKLKAKSKDIIKEKTVLLEGILGIANGENPRDLENKLLNYIAPGEPKKSQFEG
What is the function of this protein?
MotA and MotB comprise the stator element of the flagellar motor complex.  Required for rotation of the flagellar motor.  Probable transmembrane proton channel (By similarity).
What are the official names of this protein?
Motility protein A, Chemotaxis protein MotA.
What is the protein family that this protein belongs to?
Belongs to the MotA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOLC_BUCAI
Sequence: MINKNYSLSLWLKYLEQLDKKRIYNLTELKFLAKKLGLLKSESFIFTVAGTNGKGTTCAVLERLLLDSGYQVGLYTSPHLINFVERVRINGFVLHEEEHIDSFQNVELVRNGVLLTYFEFITLAALILFKRYSLDCIILKVGLGGRLDATNIIDSDISIITNIGIDHTSILGRDRISIAREKCGVFRKNKISVIGETDIPCSMYQIAKEKKTILKKIDIDWSWEKKRNYWNFFHSTIQLYNLPETQVPLSSAATALSTLYYSRFKIKEKIIRKSISNVQLPGRFQVISTFPYIIVDVAHNPNAAFYLSQKIDEINITGKIYAVVGILKDKDILGIIDPLANKIHHWFTAPLKTIRTATKHELKKFFPIHNTSILKSIEIAYKKALILVKKEDAIIIFGSFLTVSEFLSLKI
What is the function of this protein?
Functions in two distinct reactions of the de novo folate biosynthetic pathway.  Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu).  Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.
What are the official names of this protein?
Dihydrofolate synthase/folylpolyglutamate synthase, DHFS / FPGS, Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase, Folylpolyglutamate synthetase, Tetrahydrofolylpolyglutamate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
Protein: RNZ_BORAP
Sequence: MGFNINIIGTGGTRPLHNRYLSSVLIEYNGDNFLFDCGEGTQMSLRKQKISWQKIKMICITHLHADHITGLLGIVMLMSQSGETRKDPLIIAGPVGIKNYTKNNIDMLKIYTNYEIIYKEIIIDKTEKIIYEDKTKKIEYTRLKHSIECVGYLFIEKDKPGKFNTEKAEELNIPKGPIRKTLQDGKEILINGKIIKPSEILGKSKKGLKVAYITDTGYFKELIQQIKNFNLVIIESTFKNELKKEADKKLHLTAGGAANIVKQAKVLQTGLIHFSERYTLRKDLENLLKEAKLEYPDGEIFLTKDGMRLEANKNNFIIK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: DUT_MYCTA
Sequence: MSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLASTSRGDGGHGSSGGHASL
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RUVA_ALKCK
Sequence: MIDYIKGNLVAVEPAYLVVEANGIGFQIYCANPYRFINDLNREVVVPTHHYVREDSQRLFGFTTRTERLLFEKLLNVSGIGPKGALAILASGEPEDIIHAIEQEDEALLVRFPGVGKKTARQIILDLKGKLDDMAPMLEPAAGADKQQKNPQLEDALEALRALGYVEKELKKVEKQLKAETLETDEYIRRALALMLKRP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: HIS3_STRGC
Sequence: MTEVKLDFQKQGGLIPAIILDHTSKEVIMLAYLNEEAYQLTRTSGQMWYWSRSRQELWHKGATSGHYQTVKKITADCDQDTLLIEVDQLGAACHTGSKSCFFHIIWDEEDSKTD
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_STRP8
Sequence: MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSKMSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAIADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDLPLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKLRQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RS10_CLOBB
Sequence: MSKQKIRIRLKAFDHTILDQSAEKIVETAKTSGAKVVGPVPLPTEKDVVTILRAVHKYKDSREQFEIRTHKRLIDIVNPSPKTVDALMRLNLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PPK5_SHELA
Sequence: GGGGSGETSGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, FXPRL-amide, SheLa-Capa-PK.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: C3H38_ARATH
Sequence: MEMSGLGRKRVSKWDSKEDTHHHHSSVNANSASYYRDKESEPVRFNAESNGEARTRSRVSQNNDNSYFSEQDGTRQQFVRRSGSRSNSRSRSRSRSPVYRARRDAGSYDRHKTRTQVSPTPIREFNKRGSDHLFDQSRSDHYGWEDNIRKPRETKYHTDDFREEAMMEGARSSDYNNTDYPEDNSRIRRRRSEFTGEKETQRRDGGDGEGGFHRSSNIPCKFFAAGTGFCRNGKYCRFSHHVADRKQPQDNNNNFYRQDNNNHTSGHNKWNDVERLDNGRVGGIEVSRASKKGVSESKGNGSSSWIDDMEMSPDWNYGVQALKKPVKEDHSVGIIGQSSQSRVLKDDQRSSGMFSHGGRTMAEKPVAASHQSYSNSVNVAPVETFNQNHNALPYQSSLTAGGSQQVLAAAATNFSVGSNLSNLESGKVYQDNHHSTVEKPVLVQNTVSREQIDQITNISASLAQFLANGQPIPQLEQALQLPLHSESVQPNQATTQSNVVSSNPNQLWGLGMSTGAEGVPAVTASKISNVEEIQEVSLDPKENGDKKTDEASKEEEGKKTGEDTNDAENVVDEDEDGDDDGSDEENKKEKDPKGMRAFKFALVEVVKELLKPAWKEGKLNKDGYKNIVKKVAEKVTGTMQSGNVPQTQEKIDHYLSASKPKLTKLVQAYVGKIKKT
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 38, AtC3H38.
Protein: SDHD_BURP6
Sequence: MPVGRSLSLDPNLLAQLQSHSPTLWLNPHQGMPLPDFAPTAADLADADARLRRCAGLLAELFAELRLSGGLIASPLQPAEPLKRAARAGHAQAGAWYVKRDDALPVAGSIKARGGFHEVLALAESIAERHGLAGADTDRRALASGAARARFARHTVMVGSTGNLGLSIGMLASALGFRTVVHMSADAKAWKKARLRTRGVEVVEHAGDYAKAVDAGRRQAAGMPCCHFVDDEGSRMLFLGYATAAAELAAQLAQAGRPVDARHPLFVHLPCGVGGAPGGIVYGLKALYGEHVHAFVAEPTASPCVLVQLAGDAAHPRSVYDIGLDNRTEADGLAVAQASPLAAALLRAQAAGAFTVDDRQLFAHLLDARERLGIDLEPSAAAAFGGPAWIAGSDAGRAYLRGRGIDPDAATHVIWATGGSLVPAQEHRRFQAHARAQRQVGGAGA
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: NUSB_SOLUE
Sequence: MASRRRARQRALQILFIWDARKQPVEDAINAYYDTLYSDEKPERDPFVIDLVRGTVEHLAEVDDRITRHAEHWRMERMPAVDRNILRLAVYEMTRGGTPAPVTIDEALELARKFSNEESVQFVNGVLDAVRREMPEPNAPPARLNS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RK36_CUCSA
Sequence: MKIRASIRKICEKCRLIRRRRRIMVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GCH1L_SALTY
Sequence: MKNTELEQLINDKLNSAAISDYAPNGLQVEGKETVQKIVTGVTASQALLDEAVRLQADAVIVHHGYFWKGESPVIRGMKRRRLKTLLANDINLYGWHLPLDAHPELGNNAQLAALLGITVKGEIEPLVPWGELSMPVPGLELASWIEARLGRKPLWCGDTGPENVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHATERGGIRALSEWLNENTALDVTFIDIPNPA
What is the function of this protein?
Provides significant protection from radiation damage and may be involved in the degradation of radiation-damaged nucleotides.
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: CYNS_ECO57
Sequence: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARQVGAKLDLDEDAILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: RLMH_PSEA8
Sequence: MRLRLIAVGSRMPRWVEEGWQEYVKRLPAELSLELVEIPLNTRGKNADVARLIRQEGEAMLARVQPGERVVTLEVEGRPWSTEQLARELDRWRLDARTVNLMVGGPEGLAPEVCARSEQRWSLSPLTLPHPLVRILVGEQIYRAWTVLSGHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_CLOTE
Sequence: MNIAVYPGSFDPITNGHLDIIKRASQVFDKVVVGILVNPDKKGLFSIEEREKLISRVVKDMPNVEVRSFSGLLVDFMKEENIKVIIKGLRAMSDFEYEFQMALMNKKLNPDIETLFMMTCAQYSYLSSSSIKQVAMFGGCIKGLVPDEIIEDICKKSNNK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_SALTY
Sequence: MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: GATA_ANADE
Sequence: MSTPAKELCRLGLREAGAGVAAKAISSTELVEASLARIQATDGKLGAFLAVCADRARAAAKAADARAARGERRSELDGVPVAVKDLFVTKGVPTTAGSRILEGYLPPYDATVVERLEAAGAVIVGKLNMDEFAMGSSNENSAYKPCHNPWDLSRTPGGSSGGSAASVAAGQVHASLGTDTGGSIREPAAFCGVVGVKPTYGRVSRYGVVAFASSLDQVGPLAREVGDAALVLRTIAGHDPRDMTSSTRPVDDYLGPLEEGARGLRVGVPREWLSGGLDAGVEAAIRAALDTYRRLGATLVDVSLPHSKYGIGAYYLIAPAEASSNLARYDGVRYGLRAEGAKGLKEMYAESREQGLGAEPKRRIMLGTYALSSGYYDAYYLRAQKVRTLIRRDFDEAFRGCDVIAGPVTPSVAFALGERTGDPLQMYLADIFTITCNLAALPGLSVPCGLEAASGLPVGLQLVGRPFDEATLFRAARALERELGPLPAPPEP
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: MACI_PENTR
Sequence: MAEMDVSSWKPTKLETKPFSLDSGHYTALAFVLAVCVPQAPHGTALRYGLLLLQITCGVQAFLAQPPSVPDRAVLYTSGVLMGNLVARYFDRLYTTVPEKTFHRIIDSQTPEDTTQLSAPKRFFWALELFSVTRGIGWNWRVAGIPKSPVPITRFQFAAAQLLRWTVMYAGLHLVNVTCQVVSSNPNAIPSLPGNLHIYALIVCGFAITIYSHFAILMLPLSALCVGLQVGPRSWQAVASWPPNFGSVREAYSIRRFWGYTWHQQLRRQAGAPGAYLISLLPDSVMTSKRTAVKLARRYSLLMMSFVISGLIHACGTYQVTRALGLPLSDGGEMKYFALQGMAIIAEDFGCWVLGIDDRGTQPGVMRRWMGYAITLSWYIWSRVQLKGVPVALAMGIEDERGDLFAALELVRVSAVAVPGNFVAMAWELIW
What is the function of this protein?
O-Mevalon transferase; part of the gene cluster that mediates the biosynthesis of macrophorins, isoprenoid epoxycyclohexenones containing cyclized drimane moieties (PubMed:28926261).  The first step of the pathway is the synthesis of 6-methylsalicylic acid (6-MSA) by the polyketide synthase macA (PubMed:28926261).  6-MSA is then converted to m-cresol by the decarboxylase macB (By similarity).  The cytochrome P450 monooxygenase macC then catalyzes the oxidation of m-cresol to toluquinol (By similarity).  Epoxidation of toluquinol is then performed by the short chain dehydrogenase macD, with the help of macE, and a further prenylation by macG leads to 7-deacetoxyyanuthone A (By similarity).  The next step is the hydroxylation of C-22 of 7-deacetoxyyanuthone A by the cytochrome P450 monooxygenase macH to yield 22-deacetylyanuthone A (By similarity).  O-Mevalon transferase macI then attaches mevalon to the hydroxyl group of 22-deacetylyanuthone A to produce yanuthone E (By similarity).  The terpene cyclase macJ catalyzes the cyclization of 22-deacetylyanuthone A to macrophorin A (PubMed:28926261).  MacJ is also able to catalyze cyclization of yanuthone E and 7-deacetoxyyanuthone A to their corresponding macrophorins (PubMed:28926261).  The macJ products can be further modified by macH and macJ, as well as by the FAD-dependent monooxygenase macF, to produce additional macrophorins, including 4'-oxomacrophorin A, 4'-oxomacrophorin D and 4'-oxomacrophorin E (PubMed:28926261).
What are the official names of this protein?
O-Mevalon transferase macI, Macrophorins biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the wax synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: 708D1_SOYBN
Sequence: MSSSEGVVHVAFLPSAGMGHLNPFLRLAATFIRYGCKVTLITPKPTVSLAESNLISRFCSSFPHQVTQLDLNLVSVDPTTVDTIDPFFLQFETIRRSLHLLPPILSLLSTPLSAFIYDITLITPLLSVIEKLSCPSYLYFTSSARMFSFFARVSVLSASNPGQTPSSFIGDDGVKIPGFTSPIPRSSVPPAILQASSNLFQRIMLEDSANVTKLNNGVFINSFEELEGEALAALNGGKVLEGLPPVYGVGPLMACEYEKGDEEGQKGCMSSIVKWLDEQSKGSVVYVSLGNRTETRREQIKDMALGLIECGYGFLWVVKLKRVDKEDEEGLEEVLGSELSSKVKEKGVVVKEFVDQVEILGHPSVGGFLSHGGWNSVTETVWKGVPCLSWPQHSDQKMSAEVIRMSGMGIWPEEWGWGTQDVVKGDEIAKRIKEMMSNESLRVKAGELKEAALKAAGVGGSCEVTIKRQIEEWKRNAQAN
What is the function of this protein?
UDP-glucose-dependent glucosyltransferase catalyzing the c-glucosylation of the A ring of 2-hydroxynaringenin.  Also active toward phloretin, but not toward naringenin and apigenin.
What are the official names of this protein?
UDP-glycosyltransferase 708D1, UDP-glucose:2-hydroxyflavanone C-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: YCFP_ECO7I
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRNDESLNSQRTSEELHHYYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: SSRP_ENTHA
Sequence: MPKGDGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRINLKDGFVRIRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQISRLETETKNTGVTIVPLKVYIRDGYAKVLIGLAKGKKSYDKREDLKRKDVDRQIDRTLKNFSR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: KDKA_XYLFM
Sequence: MVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPVSEGGRGSAWFVEASFGNAVLRQYRRGGMIAMLNRDRYFWCGGHRTRSVLEFRLMRELISRGLPVPTPLAACYVRYGVQYRAAILIERLEGVSSLAMCIRGNSKETHWEQIGRMISRFHREGLDHADLNAHNILLDPAGQCWLIDFDRGALRIPATKWRERNLARLLRSLLKIRGERSVDAVYRDFERLRRAYDLAWSRGC
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS6_CITK8
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLLNVEAPQEVIDELETNFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDADAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: HTPX_AERPE
Sequence: MGLTVLALIGGYIVVLGVAAWALDAFTGLSGTGVAFMLSLLALAMVLVQWLFSPYIINMVYRTREPLPGEEWIVAEVEQLARRSGLKPPKVVVSEMNMPNAFAYGSPIAGSYVAVTRGLLRLLPKDEVRAVLAHEVGHLKHRDVTVILALSLIPIAAFLIGRTLVWAGILGGGGGERRGNPMALVAVGAALLAAGMVFQLIVSHFNRLREYYADAHSALVTGSPRSLQRALARIHAAYEHNPHLVEEARSNEMASMLFIVAPLTSLTASPLVDVDYLVERLKEQETNPLVELFSTHPPVSKRLRFLDRLASRIGGIEHY
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AP21_EISFE
Sequence: ACSAG
What is the function of this protein?
Displays antimicrobial activity against E. coli, S. aureus and P. aeruginosa.
What are the official names of this protein?
Antimicrobial peptide OEP3121.
Protein: RM38_YEAST
Sequence: MIFLKSVIKVIDNSGAQLAECIKVIRKGSPKSPAMVGDRIVCVIQKAKPLTQNITGTANTNRVKKGDICHAIVVRSKQRNMCRKDGSTVAFGDTACVLINKNTGEPLGTRIMANDGCVDRTLKDKGYNKICSLASRVI
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L38, mitochondrial, Mitochondrial large ribosomal subunit protein uL14m, YmL38.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.