PharMolix/UniProtQA huggingface dataset:
Protein: PG052_MONPV
Sequence: MEGSKRKHDSRRLQEQEQPRPRTPPSYEEIAKYGHSFNVKRFTNEEMCLKNDYPRIISYNPPPK
What are the official names of this protein?
Protein OPG053.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG052 family.
Protein: GPBAR_RAT
Sequence: MMSHNTTELSAIPRGVQELSLVLASLIVIANLLLALGIVLDRHLRSPPAGCFFLSLLLAGLLTGLALPTLPGLWNRSHQGYWSCLLLHLAPNFCFLSLLANLLLVHGERYMAVLQPLRPHGSVRLALFLTWISSLLFASLPALGWNHWSPGANCSSQAIFPAPYLYLEVYGLLLPAVGATALLSVRVLATAHHQLREIRRLERAVCRDAPSTLARALTWRQARAQAGATLLFLLCWGPYVATLLLSVLAYERRPPLGPVTLLSLISLGSASAAVVPVAMGLGDQRYTAPWRTAAQRWLQVLRGRPKRANPGPSTAYHSSSQCSTDLDLN
What is the function of this protein?
Receptor for bile acid.  Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production.  May be involved in the suppression of macrophage functions by bile acids.  Involved in bile acid promoted GLP1R secretion (By similarity).
What are the official names of this protein?
G-protein coupled bile acid receptor 1, Membrane-type receptor for bile acids, M-BAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LECM7_PSEPL
Sequence: MGQFTVVSLGLLAVFLSLSGAKGDNCPANWISRNGVCNKLFPDRKTWLEAEMYCRALKPGCHLASLHRDSDSTVLAWYISDHFKGAGHVWIGLRDTNRKRTWKWSDRTSTNYFSWNQGEPNNVQDNENCVHPWAPSGYLKWNDEPCASLHPFICQYKL
What is the function of this protein?
Mannose-binding lectin which recognizes specific carbohydrate structures and agglutinates a variety of animal cells by binding to cell-surface glycoproteins and glycolipids.  May be a calcium-dependent lectin (By similarity).
What are the official names of this protein?
C-type lectin lectoxin-Enh7, CTL.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: UNG_SHEFN
Sequence: MTSHWQELFEQQQSQEYYQHLQHFIASQRADNKTVYPPDDEVFTAFDLTPLSEVKVVILGQDPYHGPNQAHGLSFSVKKGIKPPPSLANIYKELTNDIEGFVTPEHGNLTSWAEQGVLLLNTVLTVEQGLAHSHAKSGWETFTDNVLLRLDQQPSPIIFVCWGNHAIKKGRLITASHHHVLNGPHPSPLSAYRGFFGCGHFSSINQLLIEQGNLAINWQV
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIF_ECOLI
Sequence: MNATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAKAPDYRTLFSNLSDQDGGAIVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPSLFVREQKSPSASVTVNLLPGRALDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLTQSNTSGRDLNDAQLKYASDVEGRIQRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTEEQYRPNGDESHAALRSRQLNESEQSGSGYPGGVPGALSNQPAPANNAPISTPPANQNNRQQQASTTSNSGPRSTQRNETSNYEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGKPLPLSNEQMKQIEDLTREAMGFSEKRGDSLNVVNSPFNSSDESGGELPFWQQQAFIDQLLAAGRWLLVLLVAWLLWRKAVRPQLTRRAEAMKAVQQQAQAREEVEDAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWINNDHE
What is the function of this protein?
The M ring may be actively involved in energy transduction.
What are the official names of this protein?
Flagellar M-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FliF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: YHEU_ECODH
Sequence: MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKRQLQCGEAVLVWSELHETVNIMPRSQFRE
What are the official names of this protein?
UPF0270 protein YheU.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: YIDE_SCHPO
Sequence: MALQVDAPDVSSYDELYNRAVELLKHQQRVLIGLAGGPGSGKSTLCAILAKAWNERFGSEIVKIIPMDGFHYSLEELDRFDNPEKARALRGAEWTFDADLFYSLVRLMKKITDRELYAPSFDHAIGDPVVDDICVEPKNRILIFEGNYLLLNKPPWSDACKLYDIKAYLPVEHSVARARVAHRHLVSGLCATEEEAIERTDRNDMINLTFVEKNMVTPDIVLQQLRLKTVKTSSL
What are the official names of this protein?
Putative uridine kinase C227.14.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MBHL_AZOCH
Sequence: MSSLPNASQLDKSGRRIVVDPVTRIEGHMRCEVNVDANNIITNAVSTGTMWRGLEVILKGRDPRDAWAFVERICGVCTGTTRWTSVRAVEDALGIQIPYNAHLIRNLMDKQLQVQDHIVPFYHLLRLDWVNPVNALKADPKATSALPAALAAHAKSSPGYFRHVQTRLKKFVESGATACSPNGYWDNPAYQAPARPDLMAVAHYLEALDVQKDIVEIHTIFGGKNPHPNYMVGGVACAINLDDVGAAGGRSTCTSLNFVLERIHEAREFTRNVYLPDVLAVAGIYKDWLYGGGLPGHNLLSYGTFTKVPGDKSSDLLPAGAIVGGNWDEVLPVDVRVPEEIQEFVSHSWYRYADETKGLHPWDGVTEPKFELGPNTKGTRTNIKELDEAHKYSWIKARAWRGHAMEVGPLARYIIAYRSGREYVKEQVDRSLAAFNQSTGLNLGLKQFLPSTLGRTLARALECELAVDSMLDDWQALVGNIKAGDRATANVEKWDPSTWPKEAKGVGINEAPRGALGHWIRLKDGKIENYQAIVPTTWNGTPRDHLGNIGAYEAALLNTRMERPDEPVEILRTLHSFDPCLACSTHVMSPDGQELTRVKVR
What is the function of this protein?
This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions.
What are the official names of this protein?
Uptake hydrogenase large subunit, Hydrogenlyase, Membrane-bound hydrogenase large subunit.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1823_MYCTU
Sequence: MAESDRLLGGYDPNAGYSAHAGAQPQRIPVPSLLRALLSEHLDAGYAAVAAERERAAAPRCWQARAVSWMWQALAATLVAAVFAAAVAQARSVAPGVRAAQQLLVASVRSTQAAATTLAQRRSTLSAKVDDVRRIVLADDAEGQRLLARLDVLSLAAASAPVVGPGLTVTVTDPGASPNLSDVSKQRVSGSQQIILDRDLQLVVNSLWESGAEAISIDGVRIGPNVTIRQAGGAILVDNNPTSSPYTILAVGPPHAMQDVFDRSAGLYRLRLLETSYGVGVSVNVGDGLALPAGATRDVKFAKQIGP
What are the official names of this protein?
UPF0749 protein Rv1823.
What is the protein family that this protein belongs to?
Belongs to the UPF0749 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTAFR_MACMU
Sequence: MEPHDSSHVDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPSKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNGGNWIFPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFFILDSTNTVPNSAGSGNITRCFEHYEKGSVPVLIIHIFIVFSFFLVFLIILFCNLV
What is the function of this protein?
Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity.  Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Platelet-activating factor receptor, PAF-R, PAFr.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIP6_ORYSJ
Sequence: MANAKQLALFAMLVLLLASCAAARRHGKPDPCDGGGGGVDSHLPPGMRRCSSPAVSEDGTPAVMTVNGFEEGEDGGGPAACDGRYHSDRSLVAALSTGWFAGGRRCHRGIRITSRQNGRSVVATVVDECDSRHGGCKDDIVDTSAAVWSALGLDTNVGEVPVTWSDA
What are the official names of this protein?
Putative ripening-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the kiwellin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDUS2_HUMAN
Sequence: MAALRALCGFRGVAAQVLRPGAGVRLPIQPSRGVRQWQPDVEWAQQFGGAVMYPSKETAHWKPPPWNDVDPPKDTIVKNITLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIRPPPRAQWIRVLFGEITRLLNHIMAVTTHALDLGAMTPFFWLFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLMDDIYQFSKNFSLRLDELEELLTNNRIWRNRTIDIGVVTAEEALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPVGSRGDCYDRYLCRVEEMRQSLRIIAQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30922174, PubMed:22036843).  Essential for the catalytic activity of complex I (PubMed:30922174, PubMed:22036843).  Essential for the assembly of complex I (By similarity).  Redox-sensitive, critical component of the oxygen-sensing pathway in the pulmonary vasculature which plays a key role in acute pulmonary oxygen-sensing and hypoxic pulmonary vasoconstriction (PubMed:30922174).  Plays an important role in carotid body sensing of hypoxia (By similarity).  Essential for glia-like neural stem and progenitor cell proliferation, differentiation and subsequent oligodendrocyte or neuronal maturation (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial, Complex I-49kD, CI-49kD, NADH-ubiquinone oxidoreductase 49 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: KAD2_CANGA
Sequence: MSSSDSIRMVLIGPPGAGKGTQAPNLVERFHAAHLATGDMLRSQISKGTELGLQAKKIMDQGGLVSDDIMVNMIKDELTNNPACKNGFILDGFPRTIPQAEKLDNMLKERGTPLEKAVELKIDDELLVARITGRLIHPASGRSYHKLFNPPKEDMKDDVTGEPLVQRSDDNEDALKKRLGAYHDQTEPIVDFYKKTGIWADVDASQPPETVWSAILKALGKN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: HIS6_NITEU
Sequence: MGLAKRIIPCLDIKDGRVVKGVNFVSLRDAGDPVEIARSYNEQGADELVFLDITASSENRDLILHIVEKVAAQVFIPLTVGGGVRKAEDVRRLLNAGADKVSINTSAVLNPMLIKESADHYGSQCIVIAIDARQIPDANPESPRWEVFTHGGRKPTGIDAIEWAQKIQALGAGEILLTSMDRDGTRSGFDLTLTRAISDSVDLPVIASGGVGHLDHLVEGILAGHADAVLAASIFHYGEYSILQAKQYLSSHGIEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGI2_MOUSE
Sequence: MALWRGGGALGLLLLSAACLIPPSAQVRRLARCPATCSCTKESIICVGSSWVPRIVPGDISSLSLVNGTFLEIKDRMFSHLPSLQLLLLNSNSFTVIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNEVTSFDYECTTTGPQTDEAKQRGWQLELSLGFCELIFVFQHPLSDFVVHQTLPYQSVSVDTFNSKNDVYVAIAQPSMENCMVLEWDHIEMNFRSYDNITGQSIVGCKAILIDDQVFVVVAQLFGGSHIYKYDESWTKFVKFQDIEVSRISKPNDIELFEIDDETFFIIADSSKAGLSTVYKWNSKGFYSYQSLHEWFRDTDAEFVDIDGKSHLILSSRSQVPIILQWNKSSKKFVPHGDIPNMEDVLAVKSFRMQNTLYLSLTRFIGDSRVMRWNSKQFVEVQALPSRGAMTLQPFSFKDNHYLALGSDYTFSQIYQWDKEKQQFKKFKEIYVQAPRSFTAVSTDRRDFFFASSFKGKTKIFEHIIVDLSL
What is the function of this protein?
Required for the development of soma-targeting inhibitory GABAergic synapses made by parvalbumin-positive basket cells.
What are the official names of this protein?
Leucine-rich repeat LGI family member 2, Leucine-rich glioma-inactivated protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_EHRCR
Sequence: MVNIVVVGLQWGDEGKGKVVDWLSTNADAVVRFQGGNNAGHTIVINDKVYKLNLLPSSVLQNNKLSIIGNGVVLDPYALVSEIDNLKSSGINITTQNLAISESCPLVLSVHKQADILFEQLRQDTIGTTNKGIGPCYADKISRRAIRVCDLLDTKDLLYSKVNHLLIYHNLLRKSLNTPPIKAEDIVNELLNIAPKILPFVQPVWKTIYNLTQQNKTIIFEGAQGTFLDIDHGTYPFVTSSNTIASQAWVGCGINPSNKSYILGLVKAYTTRVGNGPFFTEQNNDIGKIMFKTGKELGTVSNRKRRCGWFDAVLARQAIMLSGVSGLVMTKLDVLDQFSEIKICVKYKYGDKTYDYLPASPHIQSNLEPIYEILPGWQTSTFGSVSYKDLPQNAILYIKKIEEILKVPIHLISTGPERNSMIILNNDFLQ
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGSB2_DROME
Sequence: MKLQLALVLCGLTLALGQIVPRSSWCPVPISPRMPRLMVPVRLIIIHHTVTAPCFNPHQCQLVLRQIRADHMRRKFRDIGYNFLIGGDGRIYEGLGFGIRGEHAPRYNSQSIGIAFIGNFQTGLPPSQMLQAARTLIQIAVQRRQVSPNYSVVGHCQTKATACPGIHLLNELKKWPNWRPKP
What is the function of this protein?
N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN).  Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments.  Has no direct bacteriolytic activity (By similarity).
What are the official names of this protein?
Peptidoglycan-recognition protein SB2.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCME_COLP3
Sequence: MNPRRKKRLAIVGSILIGIGVVSGLVLYALSQNIDLFFTPSEITQGKKETGLKPSLGQRIRIGGLVVPGSVKRDPENLKVSFRLSDMAMPIVFKDSDPMVTVYYEGILPDLFREGQGIVANGTLTEHPPTGLSIEASEVLAKHDENYMPAELAEAAGQKHDKATYSDKQLESKKTNSY
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: CH60_CUPMC
Sequence: MAAKDVVFGDAARAKMVEGVNILANAVKVTLGPKGRNVVLERSFGGPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKTSDNAGDGTTTATVLAQSIVREGMKFVAAGMNPMDLKRGIDKAVGAAVEELKKLSKPTTTSKEIAQVGAISANSDASIGERIAEAMDKVGKEGVITVEDGKSLADELEVVEGMQFDRGYLSPYFINNPEKQVVQLDSPFVLLFDKKVSNIRDLLPVLEQVAKAGRPLLIIAEDVEGEALATLVVNNIRGILKTAAVKAPGFGDRRKAMLEDIAILTGGTVIAEEIGLTLEKATLQDLGQAKRIEIGKENTIIIDGAGDASAIEGRVKQIRAQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVPGGGVALLRARAAIAGLHGENPDQNAGIKIVLRAMEEPLRQIVLNAGEEASVVVAKVIEGKGNYGYNAASGEYGDLVEMGVLDPTKVTRTALQNAASVASLMLTTDCAVAESPKEESAPAMPGGMGGMGGMEGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBU_SYNS3
Sequence: MKRLLSWLTGLVVIAGLLIGLLVPPSVSAAEIRNVADDKLAERGDKVDLNNSSVRRFQQFPGMYPTFAGKIVLGGPYENVDDVLKLDLSERQKELFEKYRDNFVVTAPSIALNEGFDRINDGQFR
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: SYH_PSEMY
Sequence: MSKSLQAIRGMNDILPEQTPAWRYLESTLVSLLDGYGYKEIRLPIVEYTELFARGIGEGTDVVDKEMYTFLDRNEESLTLRPEGTAGCVRAVLEHGLAGGGQVQKLWYAGPMFRYEKPQKGRYRQFHQVGVEAFNLPGPDVDAELIVLTWRLWKKLGLADAVTLQLNSLGSSEARAAYRDALVAYLQERFDQLDEDSQRRLTTNPLRILDSKNEATQAVLVGAPTLGDYLDEESRLHFEGVKARLDAAGIRYQINHKLVRGLDYYNRTVFEWVTDKLGAQGTVCAGGRYDGLVAQLGGKATPGVGFAMGVERLVLLLETLDLLPAELNRAADVYVCAFGEAAELAALTLTERLRDELPGLRLLLNSGGGSFKSQFKKADKSGARYALILGDDELAGRVVGCKPLRDDSEQQSVAWDALAEHLAACQQA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_CAMFF
Sequence: MAHKKGQGSTQNNRDSIGRRLGVKKFGGEFVRAGNIIIRQRGTATHPGNNVGIGRDHTIFALVDGFVKFERKDKDRKKVSVYPAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ACCH2_ARATH
Sequence: MESTKIAPSFDRASELKAFDETKTGVKGLVDSGISKIPRIFHHSSVELANPKPLPSDLLHLKTIPTIDLGGRDFQDAIKHKNAIEGIKEAAAKWGFFQVINHGVSLELLEKMKDGVRDFHEQPPEVRKDLYSRDFGRKFIYLSNFDLYTAAAANWRDTFYCYMAPDPPEPQDLPEICRDVMMEYSKQVMILGEFLFELLSEALGLNPNHLKDMECLKGLRMLCHYFPPCPEPDLTFGTSKHSDGSFLTVLLPDNIEGLQVCREGYWFDVPHVPGALIINIGDLLQLITNDKFISLKHRVLANRATRARVSVACFFHTHVKPNPRVYGPIKELVSEENPPKYRETTIRDYATYFNGKGLGGTSALLDFKV
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase homolog 2.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: EXT1C_DANRE
Sequence: MQARKKYVLLGLCTCCWILLYYWAGLQERLLGLITHRRGEVPRPWPDWLDRALLPNFAEQLDLQNGGGPGDSPRQRKQAWSSIYKDSRCRMDTCFDFGRCQTQSGFRVYIYPPEKGERVSEGYRKILTSVSESRYYTSDPREACLFVLGIDTLDRDQLSQQFVPNVDERIRGYPLWNDGRNHVIFNLYSGTWPNYTEDLGFNVGQAILAKASLNTEHFRPGFDISIPLFSKEHPQKGGKRGWLVRNSVPPRRKYLLMFKGKRYLTGIGSDTRNALHHIHNGKDIVSLTTCRHGKDWEKHKDARCDHDNQEYERFDYQELLHNSTFCLVPRGRRLGSFRFLESLQAACIPVLLSNGWELPFSDVIQWNQAVVEGDERLLLQVPSTVRAVGIDRVLALRQQTQTLWDAYFSSVDKIVLTTLEIIKDRVYSHISRNKLMWNALPGGLLVLPEFSTHLAHYPFYYLHLGISPGLEFTAVIHATSPLVSQSQPIMKLLQVVSKSKYCSQIIILWNSEKSPPQRSKWPPMPVPLTVTDGRRKTSSRFLPHAAIETEAVLSLDEDTVLLTSEINFAFHVWRSFPDRIVGYPPRSHFWDPVKKAWGYTSKWTNEYSIILTGAAFYHRYYHHLFSHYLPSSLRALVDHSCNCEDILMNFLVSSVAHLPPVKVAQRKQYKEMPSLQGTKMAPWANPEHFTQRQECVNTFSSWFGYMPLEHSQFRLDPVLFKDHVSVLRKRYKDLERV
What is the function of this protein?
Glycosyltransferase required for the biosynthesis of heparan-sulfate.
What are the official names of this protein?
Exostosin-1c, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1c, Multiple exostoses protein 1 homolog c.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: DENR_KLULA
Sequence: MPLTNVIYCGVCDFPAEYCEFSGKFKRCKAWLQENHPELYTKWYGDVTEDVSKQLAESSIGDEREEKLEKALEKLERKQQAREERELAKKLSSKVVIRREARTKRKCMIAISGLEVFEIDMKKLSKTFASKFATGCSISKNAEKKEEVIVQGDLADEVEAYIHSLLEEKGMKEVKVEVIDAAKKKKKAETTTTPGSENKK
What are the official names of this protein?
Translation machinery-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_HAHCH
Sequence: MTERDTTHFGYKQVPVTEKESHVAKVFDSVAAKYDLMNDLMSMGIHRLWKRFTIDKSGVRAGASVLDIAGGTGDLTKKFSRLVGPSGKVVLADINASMLQVGRNQLLDHGYGDNIEFVQANAEALPFPDNSFDCVSIAFGLRNVTDKDQALREMQRVLRPGGRLLVLEFSKPTNPIVSKAYDVYSFSALPLMGSLVAQDSESYRYLAESIRMHPDQETLKSMMEQAGLCLCKYYNLTSGVVALHTGVKA
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: FZD4_CHICK
Sequence: MERRGGGGRMLALLLAGLLGGARGFGDEEERRCDAIRIAMCQNLGYNVTKMPNLVGHELQADAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPDSLNCSKFPPQNDHNHMCMEGPGDEEVPLHSKTSLQPGEECHSMGSNSDQYIWVKRNLDCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIRSNLQKDGTKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISNWAVFRYSADDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRADGWVKPGKGNETVV
What is the function of this protein?
Receptor for Wnt proteins (By similarity).  Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity).  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase (By similarity).  Both pathways seem to involve interactions with G-proteins (By similarity).  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (By similarity).
What are the official names of this protein?
Frizzled-4, Fz-4, cFz-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNP_BURCM
Sequence: MSMFNKVVKEFQWGQHKVRLETGEVARQASGAVIVDVEDTVVLATVVGAKSAKPGQDFFPLTVDYLEKTYSAGKIPGGFFRREGRPSEHETLTSRLIDRPLRPLFPEGFYNEVQVVIHVLSVNPEIPADIPALIGASAALAVSGLPFNGPVGAARVAYIDNAYVLNPTRDQLKASSLDLVVAGTERAVLMVESEADQLPEDVMLGAVVFGHEQMQTAIDAIHELVREGGKPEWDWQPAPKNEALIARVTELAHGDLLAAYQLRDKQARSTKLKEVYAATSAKLEEDAQAAGTVAADKATVGNVLFDIEAKIVRSQILNGEPRIDGRDTRTVRPIEIRTGVLPRTHGSALFTRGETQALVVATLGTKGDEQIIDALEGEYRERFMLHYNMPPFATGETGRVGSPKRREIGHGRLAKRALVKCLPSADEFGYSIRVVSEITESNGSSSMASVCGGCLALMDAGVPMKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTEQGVTALQMDIKIQGITKEIMQVALAQAKEGRMHILGKMTSAVSGANTQLSEFAPRMITIKINPEKIRDVIGKGGSVIRALTEETGTTIDISDDGVVTIASTSSEGMAEAKKRIENITVEIEVGQVYEGTVLKLLDFGAIVNLLPGKDGLLHISEIVNERVKDINDYLKEGQQVKVKVIQTDEKGRVRLSAKALLNEAAASQSDTPPQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.