PharMolix/UniProtQA huggingface dataset:
Protein: PLK4_DANRE
Sequence: MSVSIGDKIEDFKVLTLLGKGSFACVYRAKSVNTGLEVAIKMIDKKAMHKAGMVQRVINEVEIQCRLKHPSVLELYNYFEDSNYVYLVLEMCHNGEMSRYLKERKNPFTEEEARHFMHQIVKGMLYLHTHGIMHRDLTLTNLLLTTSMNIKIADFGLATQLKLPSEKHFTMCGTPNYISPEVATRSAHGLESDVWSLGCMFYAFLTGRPPFDTDTVKRTLNKVVLGEYQMPMHISAEAQDLIQQLLQKNPALRPSLSAVLDHPFMTQSGPTASKDSGSSNGGSIDSGIATISTASNATNNSSSSRLQRRTRQMIGQPLPSRMAPIPSHSHHSTSSSFKSGQDWQPNSQDDLSRMGVGRIPVGADSGRPHSRYLRRAHSSDRSAVGYSHNPQEAELERCHSEEMLSGAGRLFPQTSGYRNAPHGYSKHDRLPSPPVKQPANPASSFSTSTHSTRQQMPDSQTQPWFSNDGVFKRPADMSGHSSSGSFHSERGPIGTQTSCSDKPSGLHSQQQPILFQHNNPGPCREDAFVSGHMSEPQAYSDAQFPCPPLSKGKANTEKKDKVCLKKSFPPLCAARLKPIRQKTKNAVVSILGNGEVCMELLKGQGAQERVKEVLRISCDGSMVTVYQPNEGKGFPVLDHPPSPPEDILICSFDDLPEKYWKKYQYATKFVQLVKSKTPKVTLYTKFAKCMLMENSPNPDLEVCFYDGAKTHKTSEQVRVVEKSGKSYTVKGDVGLSGLNPECRLYIELSEEGHRMCLSLEAAITAEEQRSAKNTPFFPITIGRRPVNPVPPAPAPSSSSSCRPAAAAEVAHVCLSPPQHPQITPSMISYAGSDLTTASVAKGSSPVHKDERTVNSGKVLKSIFVPNIGWVSQLTTGEVWVQFNDGSQLMVQVGVSCIIFTSPEGHITRYKENEKLPELVKEKLHCLSSILGLLANPAARC
What is the function of this protein?
Serine/threonine-protein kinase that plays a central role in centriole duplication.  Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as sass6, cenpj/cpap, ccp110, cep135 and gamma-tubulin.  When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase.  Its central role in centriole replication suggests a possible role in tumorigenesis, centrosome aberrations being frequently observed in tumors.  Also involved in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PLK4, Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase Sak.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrioles throughout the cell cycle. Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles (By similarity).
Protein: RL1_STRPG
Sequence: MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEVAYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVAKINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQGVGIKVDPNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MYH11_RAT
Sequence: KKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDSSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRHARDERTFHIFYYLIAGAKEKMRNDLLLESFNSYTFLSNGFVPIPAAQDDEMFQETLEAMSIMGFSEEEQLAILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKEQADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTASKVIQRNCAAYLKLRNWQWWRLFTKVKPLDEEMEAKQNLERHVSTLNIQLSDSKKKLQDLASTIEVMEEGKKRLQKEMEGLGQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMRTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAVKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATSKENEKKAKSLEAELMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELVTERSAAQKNESARQQLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIVQLEEQIEQEAREKQAATKLLKQKDKKLKEVLLQVEDERKMVEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNEASFVPSRRAGGRRVIENTDGSEEEMDARDSDFNGTKASE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-11, Myosin heavy chain 11, Myosin heavy chain, smooth muscle isoform, SMMHC.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Melanosome. Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: CMOB_ALCBS
Sequence: MLTDYLQACERGLEPLFSPQILSAVMALSRQRLVERPHGDLPRWMAALDALPAGPTNCALDQNTLTIGRAGEQNEEAVKLALQGLIPWRKGPFEFFGVPVETEWRSDWKWQRVAPHLSSLQGRRILDVGCGSGYHCWRMAAAGASCVVGIDPTILFLVQYLAVRRFAPDLPVWFLPLRMEELPAEGGQFDTVFSMGVLYHRRSPLDHLLELKGALCAGGELVLETLVVEGDECTVLMPQDRYAMMRNVFFLPSVAMLSRWLERCGFVDVRCVDESNTSVQEQRSTDWMRFQSLPDFLDPEDHSLTREGYPAPRRAVLVARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: ILVD2_NOCFA
Sequence: MPELRSRTVTHGRNMAGARALMRASGVPAADIGAKPVVAVANSFTEFVPGHTHLQPVGRIVGDAIRRAGGIPREFNTIAVDDGIAMGHQGMLYSLPSRDLIADSIEYMVQAHCADALVCISNCDKITPGMLLAAMRLDIPTVFVSGGPMEGGRATLADGTVRRLDLITAMSEAVNDATSDADLATIEENACPTCGSCAGMFTANSMNCLVEALGLALPGNGTTLATHTARRDLYEAAGATIMAITRRYYDRDDATVLPRAIASRAAFDNAMALDLAMGGSTNTVLHLLAAAHEAGLDYTLADIEKRSRAVPCLCKVAPNGSHLMEDVHRAGGIPAILGELRRGGHLHTTVRAVHSESLDGWLAEWDVRGPNPAQAAVDLFHAAPGGVRSATAFSQSARWAALDLDAESGCIRDVAHAYSEDGGLAVLRGNLAVDGAVVKSAGVPADLHVFTGEAVVAESQEEAVTAVLSGRVRPGTVLVIRYEGPRGGPGMQEMLYPTAYLKGRGLAGSVAVVTDGRFSGGSSGLSIGHVSPEAAAGGTIAAVTDGDPITIDIPSRTLRLEVDDAEIARRLAHRRRTGYRPRSRHRPLSTALRAYALLAQSADKGGVRRLPPDELGGPEAAFDTQTRAG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase 2, DAD 2.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RDGC_YERP3
Sequence: MLWFKNLMVYRLSREVSLSADEMEKQLSAFSFTPCGSQDMAKTGWVSPMGSHSDALTHTVNGQIVICARKEEKILPSPVIKQELQDKIERLEGEQHRKLKKTEKDSLKDEVLHSLLPRAFSRFNQTFLWIDTVNDLIMVDAASAKRAEDTLALLRKSLGSLPVVPLTLENPIELTLTEWVRSKTLPAGFALMDEAELKAILEDGGVIRCKKQDLFSDEIAVHIEAGKLVTKLALDWQERIQLVLSDDGSLKRLKFADTLRDQNEDIDREDFAQRFDADFILMTSELAALIKNLIEALGGEAQH
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RBM46_HUMAN
Sequence: MNEENIDGTNGCSKVRTGIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQHLNGQISPNSENLIVFANKEESHPKTLGKLPTLPARLNGQHSPSPPEVERCTYPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYKIVIPAIANGSQSYFMPDKLCTTLEDAKELAAQFTLLHLDYNFHRSSINSLSPVSATLSSGTPSVLPYTSRPYSYPGYPLSPTISLANGSHVGQRLCISNQASFF
What are the official names of this protein?
Probable RNA-binding protein 46, Cancer/testis antigen 68, CT68, RNA-binding motif protein 46.
Protein: DIT_BPLSK
Sequence: MVRQYKIHTNLDGTDDKVLDVTNGKVRLYQPSNLGLQSTNNIWQSNGIGVMGKRSITQPQIEFKLETFGESLEENYQLMKDFVNDILSKKFVTLEYQTEIFQVYADLALADVTKTEGYGKNGTFSEKITFDIITKWYTYENLTFDKIENGKVIAGMSKVYGGTELGGYKYIEGTSYTYYGETNIERLSRWDIKDEIFSFMGILYPQLPKTPAGVRFLDDTGNEYTAIVFKTEQAQDYILINTDVNDEVYQGWNGTTSLNLFPVMDFERYRTRIIEKGQMELINLSKAEFKIKRKADFV
What is the function of this protein?
Forms the distal part of the tail.  Self-associates as two rings organized back to back, with a central channel allowing DNA ejection.
What are the official names of this protein?
Distal tail protein, Dit, Gene product 15, Gp15.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus distal tail protein family.
What are the subcellular locations of this protein?
Virion. Note=Part of the tail.
Protein: NGFV_PSEPO
Sequence: MSMLCYTLIIAFLIGIWAAPKSEDNVPLGSPATSDLSDTSCAQTHEGLKTSRNTDQRHPAPKKADDQELGSVANIIVDPKLFQKRQFQSPRVLFSTQPPPLSRDEQSVEFLDNEDALNRNIQAKRQNHPVHDLGEQSVCDSISEWVTKTTATDIKGNTVTVKVDVNLNNQVYKQYFFETKCRNPNPVPSGCRGIDSSHWNSYCTTTQTFVRALTMEGNQASWRFIRIDTACVCVISKKT
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor, v-NGF, vNGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRF_METBF
Sequence: MEKKSCMILALDVSDREEALKIAEDVSEFVDAIKVGYPLILATGLGIIRELAEFAPIIADFKVADIPNTNRLICEHVFEAGTDAVIVQGFTGRDSLDACIEIASEYGKDVFVVSEMSHPGGAEFLQPVGEAIARMAAEAGAFGLVAPATRPERVTTIRKIIGNKLTIISPGVGAQGGKASDVIAAGADWVIVGRAIYKAESPREAARKIAAEIEAEFEQEN
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: DAPB_YERP3
Sequence: MTDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNVIVGDDLSQLTDNFDVLIDFTRPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAADIGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIADAMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSRMTFAHGAVKSTIWLGKHDNGLFDMRDVLNLNEL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_XYLFA
Sequence: MSLTNEKIVEAIAEKSIMEVMELVKAIEDKFGVSAAAPVMVSGSAAAAAPVEEQTEFTVTLKEAGAKKVEVIKAVRAVTGLGLKEAKDLTEAGGILKEAVSKEEAEKVKKELEAAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: GUC1A_LITPI
Sequence: MGNMDGKTVEELSATEIHRWYKKFMTECPSGQLTQHEFKQFFGLKNLSPASNQYIEQMFDTFDFNKDGYMDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCNDEMTAEEFTDMVFDKIDINGDGELSLEEFIEGVQKDELLLEVLTRSLDLKHIVYMIQNDGKRMEISERPRQEITTGNSLP
What is the function of this protein?
Regulatory protein that inhibits guanylyl cyclase when free calcium ions concentration is elevated.  This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure.
What are the official names of this protein?
Guanylyl cyclase-activating protein 1, GCAP 1, Guanylate cyclase activator 1A.
Protein: UBP51_MOUSE
Sequence: MRGTQGAQEMKPELWPEPKPTSENLTSRGSGSYEKVLPSIPAACHTSSSSVCPRRKPRPRPQPRSRSRGGRGLKAPPPPPAKPPPPPPAPPPPPLPKQRSVAWRNSRRRSRPGPRPQTRKSYSSDHGSSRDSDGSENSLLEVGSNKGPTGCCHVESFKVAKNWQRNLRMIYQRFIWSGTPETRKRKAKSCICQICSTHKNRLHSCLSCVFFGCFTDKHIHIHAETTQHNLAVDLCHGVIYCFMCRDYVYDKDIEKIAKETKEKILGLLSSPTGDASYQQLMASEVEENQLTCESKDQETSLVKPKKKRRKKTMYYTVGFRGLINLGNTCFMNCIVQVLTHIPLLKEFFLSNKHKCMMTSPSLCLVCEMSLLFQAMYSGNQSPHIPYKLLHLIWIHAEHLAGYRQQDAQEFLIAILDVLHRHSRDDGIDQEGNSNCCNCIIDHIFTGSLQSDLTCQVCHGVSTTIDPCWDISLDLPGPYTPGRASSSTSSRDGQKPRVISLTDCLKWFTRPEDLGSSAKIKCSQCQSYQESTKQLTMKKLPIVACFHLKRFEHLGKQRRKINSFISFPLELDMTPFLASTKESIMKGQPLTECVPSENKYSLFAVINHHGTLESGHYTSFVRQEKDQWFSCDDAVVTKATMEELLNSEGYLLFYHRQDIEKE
What is the function of this protein?
Deubiquitinates histone H2A at 'Lys-13' and 'Lys-15' and regulates DNA damage response.  USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1 foci.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 51, Deubiquitinating enzyme 51.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Chromosome. Note=Dissociates from chromatin immediately after DNA damage and reassociates with chromatin following DNA repair.
Protein: CALM_PLAFA
Sequence: MADKLTEEQISEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEIDTDGNGTIDFPEFLTLMARKLKDTDTEEELIEAFRVFDRDGDGYISADELRHVMTNLGEKLTNEEVDEMIREADIDGDGQINYEEFVKMMIAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+) (By similarity).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity).
What are the official names of this protein?
Calmodulin.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=In trophozoites and schizonts, localizes throughout the cytoplasm (PubMed:3313391). In merozoites, localizes to the apical complex (PubMed:3313391).
Protein: SPEE_CLOK1
Sequence: MDLWLREGQIEDAAMTYKIKETLVTKKTKYQELAIVDTYALGRMLVLDGIVQTTVKDEYVYHEMITHIPLFTHPNPQKVLIVGGGDGGTVREVLKHETVEKVVLCEIDEQVVYECKKYLPEISCELDNPKCEVFIGDGIKYVHQHRNEFDVIIVDSTDPFGAAEGLFGGSFYKEIYNCLTEDGIFIAQTETPFYLPEVVKQVYKDAKEIFPITRLFMAGIPTYPSGFWSFTIGSKKYDPKEVDLSSTLNINTKYYTKELHKACFVLPKFVEDLTR
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_YERPS
Sequence: MKQLTILGSTGSIGNSTLSVVRANPELFKVTALVAGRNVREMAQQCLEFSPRYAAMSDEHSAKSLRLLLAEQGSDTEVYSGETAACELAALDDVDQVMAAIVGIAGLPSTLAAIRAGKQVLLANKESLITCGKLFMDEVKRSRAQLLPIDSEHNAIFQSLPERIQRQLGYSSLNENGVSRIILTGSGGPFRETPLSQFSDVTPDQACAHPNWSMGRKISVDSATMMNKGLEYVEARWLFNASAEQIEVVLHPQSVIHSMVRYHDGSILAQMGTPDMRTPIAHAMAYPMRVSSGVAPLDFCKVGALTFTTPDYQRYPCLKLAIDACNAGQAATTALNAANEISVMAFLDSKIRFTDIEVINRTVVEGLLLSEPTSVEEVLVIDRKARDVAAQVIAKLNN
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: PG190_VACCW
Sequence: MKTISVVTLLCVLPAVVYSTCTVPTMNNAKLTSTETSFNDKQKVTFTCDQGYHSSDPNAVCETDKWKYENPCKKMCTVSDYISELYNKPLYEVNSTMTLSCNGETKYFRCEEKNGNTSWNDTVTCPNAECQPLQLEHGSCQPVKEKYSFGEYMTINCDVGYEVIGASYISCTANSWNVIPSCQQKCDMPSLSNGLISGSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPVLPICVRTNEEFDPVDDGPDDETDLSKLSKDVVQYEQEIESLEATYHIIIVALTIMGVIFLISVIVLVCSCDKNNDQYKFHKLLP
What is the function of this protein?
Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells.  Participates also in wrapping mature virions (MV) to form enveloped virions (EV).
What are the official names of this protein?
Protein OPG190, Plaque-size/host range protein.
What is the protein family that this protein belongs to?
Belongs to the receptors of complement activation (RCA) family.
Protein: RSC1_YEAST
Sequence: MVEQDNGFLQKLLKTQYDAVFHLKDENGIEIYPIFNVLPPKKEYPDYYIIIRNPISLNTLKKRLPHYTSPQDFVNDFAQIPWNAMTYNAKDSVIYKYAILLESFIKGKIVHNIRKHYPEVTYPSLGRIPEIFAESMQPSDLSSNPINTQENDEKAGLNPEMKMAFAKLDSSITERKPTNQDYRMQQKNSPAFPTHSASITPQPLASPTPVVNYANITSAHPKTHVRRGRPPVIDLPYVLRIKNILKMMRREVDQNNKTLTLCFEKLPDRNEEPTYYSVITDPICLMDIRKKVKSRKYRNFHTFEEDFQLMLTNFKLYYSQDQSNIIRAQLLEKNFNRLVRIELSKPDEDYLPEGELRYPLDDVEINDEKYQIGDWVLLHNPNDINKPIVGQIFRLWSTTDGNKWLNACWYFRPEQTVHRVDRLFYKNEVMKTGQYRDHPIQDIKGKCYVIHFTRFQRGDPSTKVNGPQFVCEFRYNESDKVFNKIRTWKACLPEELRDQDEPTIPVNGRKFFKYPSPIADLLPANATLNDKVPEPTEGAPTAPPLVGAVYLGPKLERDDLGEYSTSDDCPRYIIRPNDPPEEGKIDYETGTIITDTLTTSSMPRVNSSSTIRLPTLKQTKSIPSSNFRSSSNTPLLHQNFNQTSNFLKLENMNNSSHNLLSHPSVPKFQSPSLLEQSSRSKYHSAKKQTQLSSTAPKKPASKSFTLSSMINTLTAHTSKYNFNHIVIEAPGAFVVPVPMEKNIRTIQSTERFSRSNLKNAQNLGNTAINDINTANEQIIWFKGPGVKITERVIDSGNDLVRVPLNRWFCKNKRRKLDYEDIEEDVMEPPNDFSEDMIANIFNPPPSLNLDMDLNLSPSSNNSSNFMDLSTIASGDNDGKECDTAEESEDENEDTEDEHEIEDIPTTSAFGLNSSAEYLAFRLREFNKL
What is the function of this protein?
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning.  RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA.  The reaction requires ATP and involves an activated RSC-nucleosome intermediate.  Remodeling reaction also involves DNA translocation, DNA twist and conformational change.  As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton.  This subunit is involved in meiotic sporulation through regulating IME2 expression.
What are the official names of this protein?
Chromatin structure-remodeling complex subunit RSC1, RSC complex subunit RSC1, Remodel the structure of chromatin complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the RSC1 family.
Protein: MUTS2_AGARV
Sequence: MNKKVYKTLEYNKILTMLSSYAACDETKKRCLSLEPITDLYEIRHLQTTTADALSRLYKDSGVSFVGIHNVHASLKRLDIGGALNTTELLRICSLLEVAKRVKAYGRSAMDNEKQDSLSGLFAGIEPVSALCDEIKRCILSEEEIADDASPELFKIRKSIRGMNDRIHAQLTKLMNNSTTRTYLQDAVVTMRDGRYCLPVKAEAKGNVPGMMHDQSSTGSTLFIEPMAVVNLNNELKELFIKEQEEIEKILAALSDKVAMNAAALEQDYEILSELDFIFAKANLAKSYNGVAPDFNTDGHINIRKGRHPLLDAKKVVPIDVRLGEDYKQLIITGPNTGGKTVSLKTVGLLTLMGQAGLHIPAADRSKLAIFEDVFADIGDEQSIEQSLSTFSSHMTNIVKILEKADDRSLCLFDELCSGTDPTEGAALAISILNRLHQYGAITMATTHYSELKVYALSTDGVENACCEFNVETLSPTYRLLIGIPGKSNAFAISSKLGLDENIIEDAKSRINDNDLDFEDLIASLESQRQTIEKEQLEINSYKAEIEKLKKQLEEKNERIDKSKDKILREANEEAYKILQDAKELADKTIRNFNKYGQGQAPMSQMEKERSALRDKMNDKEKKLSDIKKNTAKANHKAPKKLRIGDSVLVLSLNLKGTVHTLPNAKGDLYVQMGILRSLVNINDLVLLNDDVSPAKKYGGSGSKIKMSKSLSVSSEINLIGKTTDEALALLDKYLDDAYIAHLSSVRIVHGKGTGALRKAVHGLLKRTKTIAEYHLGEFGEGDAGVTIATFK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: HACD1_HUMAN
Sequence: MGRLTEAAAAGSGSRAAGWAGSPPTLLPLSPTSPRCAATMASSDEDGTNGGASEAGEDREAPGERRRLGVLATAWLTFYDIAMTAGWLVLAIAMVRFYMEKGTHRGLYKSIQKTLKFFQTFALLEIVHCLIGIVPTSVIVTGVQVSSRIFMVWLITHSIKPIQNEESVVLFLVAWTVTEITRYSFYTFSLLDHLPYFIKWARYNFFIILYPVGVAGELLTIYAALPHVKKTGMFSIRLPNKYNVSFDYYYFLLITMASYIPLFPQLYFHMLRQRRKVLHGEVIVEKDD
What is the function of this protein?
In tooth development, may play a role in the recruitment and the differentiation of cells that contribute to cementum formation.  May also bind hydroxyapatite and regulate its crystal nucleation to form cementum.
What are the official names of this protein?
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1, 3-hydroxyacyl-CoA dehydratase 1, HACD1, Cementum-attachment protein, CAP, Protein-tyrosine phosphatase-like member A.
What is the protein family that this protein belongs to?
Belongs to the very long-chain fatty acids dehydratase HACD family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y286_ATV
Sequence: MVRILNFFEINENASDQENIISAPYDVYIPLMREKYEQIKLGRYDKTEYPENFPQQYRTGRGIAYFSEMVYEAFRGGLFNQFIVEGQQGAGKSSFALWVARAIYGNWHDALKHVVIDPFQLRQIILVAEANSITIPLIVVDDAGLFFSKGLAYRRQTGRMQTIQRLLQVIRTAVSNIILTTPNEEELSGIVIRQPKQYKIIIEKQNELVSKARVYEEEIQPLRGKKITRRLKLRDDIEKNLRTPLDFLEVAQNAHEVNLPRHIDDTAYQIYMKLRGLYTAIALRTS
What are the official names of this protein?
Uncharacterized protein ORF286.
Protein: Y1704_LACJO
Sequence: MTEPIIEFKDFSFKYNSQAEPTLKNINLKINKGEKILLAGPSGSGKSTIGRCLNGLIPNIDQGEVKGKCLVNGKDITSTSLFDFSFTTSTILQDADSQFIGLTVGEDIAFALENDCQPKDKMHQTVNQWANELKIKELLTQSPQSLSGGQKQIVALAGVLVDESPILLFDEPLANLDPASGLKTMAIIDKIQKELNATVIIIEHRVEEVLSQLIDRIILVNEGTIVADQPTNQLLHSNTLEKIGVREPLYLKALTAADVNLSSIKEVDQISTLPVSEKISDKLAAWTKQAKITKKEVDNLPLLKLDHVGHQYSKNQPYPLKDVSTTINQGDFISIVGQNGAGKTTLCRTICGFISNEGKITLKDQNLSDLSIKERAEKIGYVMQDPNQMISQKMIFDEIALGLRLRNVDEETIKQKVDQTLKICGLYPFRHWPISALSFGQKKRVTIAAILVLEPEIIILDEPTAGQDWKTYTEIMSFLKHLNTMGKTIIIITHDMHLMLEYTSRSLAFAKGKLIADTTPIELLTNQALIKEASLKRTSLYDLAKHYNLPDPNKFVQAYINFEQQNWKDEDYE
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein LJ_1704.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS16_PSESM
Sequence: MLTIRLALGGSKKRPFYHLTVTDSRNARDGSHKEQIGFFNPVARGQEIRLSVNEERVNYWLSVGAQTSERVAQLLKEHNKTKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.