PharMolix/UniProtQA huggingface dataset:
Protein: TRPA_PSE14
Sequence: MSRLEQRFAQLKTEGRAALVTFITAGDPGYDTSLQVLKGLPAAGADVIELGMPFTDPMADGVAIQLATLRALDAGQTLQKTLQMVSEFRVDDQTTPIVLMGYYNPIHRFGVEAFVAQAKEAGVDGLIIVDLPPEHDAELATPAQASGIDFIRLTTPTTDDARLPRVLERSSGFVYYVSVAGVTGAGSATTEHVTEAIARLRRHTSLPISVGFGIRTPEQAAAIARLADGVVVGSAFVDKIATAESPEKAIDGVLTLCAALAEGVRNARIG
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TUSA_KLEP7
Sequence: MSELFSTPDHTLDALGLRCPEPVMMVRKTVRTMPVGETLLIIADDPATTRDIPGFCRFMEHELVAQETEALPYRYLIRKSH
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H4_HOLTU
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYCEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: A16L1_MOUSE
Sequence: MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLTQKLQAEKHDMPNRHEISPGHDGAWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEIQMNEAKISEYLQTISDLETNCLDLRTKLQDLEVANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAVSRAATKRLSQPAGGLLDSITNIFGRRSVSSIPVPQDIMDTHPASGKDVRVPTTASYVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESVVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAVKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSVDKGSRAVLWAQP
What is the function of this protein?
Plays an essential role in both canonical and non-canonical autophagy: interacts with ATG12-ATG5 to mediate the lipidation to ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAPL1, GABARAPL2 and GABARAP) (PubMed:12665549, PubMed:18849966, PubMed:23392225, PubMed:24553140, PubMed:24954904, PubMed:33586810).  Acts as a molecular hub, coordinating autophagy pathways via distinct domains that support either canonical or non-canonical signaling (PubMed:33586810).  During canonical autophagy, interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to ATG8 proteins, to produce a membrane-bound activated form of ATG8 (By similarity).  Thereby, controls the elongation of the nascent autophagosomal membrane (By similarity).  Also involved in non-canonical autophagy, a parallel pathway involving conjugation of ATG8 proteins to single membranes at endolysosomal compartments, probably by catalyzing conjugation of phosphatidylserine (PS) to ATG8 (By similarity).  Non-canonical autophagy plays a key role in epithelial cells to limit lethal infection by influenza A (IAV) virus (PubMed:33586810).  Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (By similarity).  Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response. Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway (PubMed:24238340).  Plays a role in regulating morphology and function of Paneth cell (By similarity).
What are the official names of this protein?
Autophagy-related protein 16-1, APG16-like 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ATG16 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Note=Recruited to omegasomes membranes by WIPI2 (PubMed:24954904). Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5 (PubMed:24954904). Localizes also to discrete punctae along the ciliary axoneme (PubMed:24954904). Upon activation of non-canonical autophagy, recruited to single- membrane endolysosomal compartments (By similarity).
Protein: HIS8_ECO45
Sequence: MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVEFQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTLENWQLDLQGISDKLDGVKVVYVCSPNNPTGQLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLVGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAEREYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCLRITVGTREESQRVIDALRAEQV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ARNB_ECO8A
Sequence: MSEFLPFSRPAMGVEELAAVKEVLESGWLTTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: RL11_STAA3
Sequence: MAKKVDKVVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTQDQAGLIIPVEISVYEDRSFTFITKTPPAPVLLKKAAGIEKGSGEPNKTKVATVTKDQVREIANSKMQDLNAADEEAAMRIIEGTARSMGIVVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: Y301_ATV
Sequence: MAHFTLDTFTFNKDVRKVSFGEYNIRPPLIKPSKLTYVENGGVGKELSDGWALNFAIGCIHACPFCYVDNIHKRFTFARVGDVVQRPWGMYFLKPRNIDEAIKKTPWKRWKGKLVMMSSTHDPYLPQLYPTSRKILEKALPAGVKFLIQTRSVLVTKDLDLLSEYKDQVILQVSIATLEEKFASIIEPRAPPPKARLEVLRKAKEVGLKVGVIVAPIFPPNKVREDVKEDLEMIMKELADIGVDQVFGEMLHERGMNMEYIESLLWEKVKIDKELDEELGKMFTELLNKYHLRGKWWYEKH
What are the official names of this protein?
Uncharacterized protein ORF301.
Protein: NADD_LEPIC
Sequence: MNSSILTGIFGGSFDPPHEGHSEILKSFFLEVPDCKEVFVIPNRQNPLKEEKISLSENILEMLNLFVSEFSQSIRILDLELKRSGPSYTIQTIQELKTIYPNRKFVLLIGEDNYSNFHKWKDWEKILTEVETIFVFRRFSKEVPLNSHLNSLFEFKFLENPLIPVTSTDLRKSFFQSKVPNLISKKVLDYILKNKLYSK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: GPMA_NEIG1
Sequence: MELVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRAIKTCNIVLEESDQLFVPQIKTWRLNERHYGRLQGLDKKQTAEKYGDEQVRIWRRSYDTLPPLLDKDDAFSAHKDRRYAHLPADVVPDGENLKVTLERVLPFWEDQIAPAILSGKRVLVAAHGNSLRALAKHIEGISDEDIMGLEIPTGQPLVYKLDDNLKVIEKFYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: SYGA_STRPG
Sequence: MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFEKFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGFPLLDEATRAILLAEDDE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_OCEIH
Sequence: MQPVTIALAKGRPAKQTIKLLQAAGLTFEELDATSRKLVFYNEDRTARVIFLKGMDVPIYVEKGAADIGIVGKDNIIESQAEVYELLDLGIGKCKFSIAAKQGVTLSSDNEITIATKYPIVAKRYFSKRNQSIDVVKLNGSVELAPLIGLADYIVDIVETGNTLRENGLEILEDIETISTKAIVNKASFATRSAEIQSIINRLSTVVG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_POLSJ
Sequence: MFAPLQNDTFLRACLRQATDYTPVWLMRQAGRYLPEYRATRARAGSFMGLATNTDYATEVTLQPLERYPLDAAILFSDILTVPDAMGLGLSFALGEGPRFATPVRDEAAVARLEVPDMGKLRYVFDAVTSIRKALNGRVPLIGFSGSPWTLACYMVEGAGSDDYRLVKTMLYQRPDLMHKMLAVNADAVAAYLNAQIEAGAQAVMIFDSWGGVLADAAFQTFSLAYTARVLGQLKREHDGVKIPRLVFTKGGGQWLQAMAALDCEVLGLDWTVNLAQARARVGENGPHAKALQGNLDPNVLFASPAQIETEVAAVLDSFGRPHLDSSQPGPTHIFNLGHGISQHTPPESVEVLVNAVHTHSRSMRAVRT
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCFP_SALNS
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLVSYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVVFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRHDEALDSQRSAQALHPFYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: BLI1_ASHGO
Sequence: MNEKQLRQQLDRCLDHVQEHVDMLSARAISKLSGDAVANHEWLSELSGRYPTRSAEELQQFRELKDGYVKKLDTLETEVKYLEDLGQELAEFQNELSVKLQRIRRNSYVQEN
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLI1, BLOC-1 subunit BLI1, BLOC-1 interactor 1.
What is the protein family that this protein belongs to?
Belongs to the BLI1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: AGUA_MYCCT
Sequence: MSKKMNSTPKKDGFWMPGEWEKHDQCWMIWPERSDNWRLGAKPAQRVFANVANAIAKYEKVTMLVSHQQFENARNLLDQNVRVIECSNDDSWMRDVGPTIVKNKDGEIRGVDWVFNAWGGFKGGLYFPWDKDDAIARKVCEISNIDYYRTDFVLEGGSIHTDGDGTLYTTEECLLNENRNPDLSKEQIEENLKEYCGVEKVIWLPLGVYNDETNGHVDNLLHVVSPGHVVLTWTDDTTDPQYERSKLAYDILTNTLDAKGRKIKVTKLHQPGPLFITKEEAEGIDVCDTMSREPEQRMPASYANFYIANNAIILPIFGDKYDDLAVKTLQSVYPNHKIETVMAREILLGGGNIHCITQQQPTTK
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: SYFB_CAEEL
Sequence: MPTVGIKKVILDKHFKRVYSEKEFDELCFEYGLELDEITSEKAAVEKEQGTRAASDLNDQEVYKIDIPANRYDLLSVEGLARAIRIFKQEIPSPAYKYADVPKTGLQKIIVKKETAQVRPFVVGAVLRDISFDADSYASFIDLQDKLHQNICRKRTLVAIGTHDLDTIQGPFEYRAEAPKDIKFKPLNQTKEYTAEELMTLYSTDSHLKAYLPIIQNHPVYPVIYDKNGVVCSMPPIINGEHSKITLNTKNVFIEATATDKQKAFVVLDTIVTLFSQYCAKPFTIEQVEVVYEETGVKELYPLLSYREMTVTTPEINTKIGINLKDEEMATLLNKMSLKAEVAAKETLKIVVPPTRHDILHACDIAEDVGVAFGYNNLITKLPESNTVAVAFPINKLCDNLRIEIAAAGWTEALNFALCSRDDISSKLRQPDALSHAVHIGNPKTLEFQVARTSLLPGLLKTLSSNRDMPLPLKLFELQDVIVKDSNTDVGARNERRLAAVYYNRAAGFEIIQGFLDRIMRMLNVNPARDGTGYYIEADENSTYFPGRCAKIIGPKGVVLGHIGALHPEVITSFGLTLPCGAVEINVEPFL
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_CLONN
Sequence: MENIKIIPSELNGEINIPPSKSLAHRAIISAGLSEGVSNIENIIFSEDIKATIRGMKSLGIEIEDITNEYKKGSERSTLKVIGKEKLTLENDTIDCSESGSTLRFLIPIALRAEKEVTFTGRGKLVSRPLDVYYNIFENQGIKYKTSNNELPLTVDGKINPGEFHVKGNVSSQFITGLMYTLPFLDGDSKIIITTELESKGYVDLTIDTLKKFGVEIENNNYKEFIIKGNQKSTSRDYRVQGDFSQGAFFIVAGILGSNVKTLDLDIDSLQGDKAIIDIVKKMGANIKVGRDYIETKKSKTHGITIDASECPDLVPILAVLGAVSHGTTKIINAERLRIKECDRLKAMATELSKIGADIKELEDGLIIKGKYKLKGGVVDSWNDHRIAMAMAIASIKCTEPVIIQNSMAVNKSYPDFWKDFEKVGGIIDEWSMGK
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MKRN2_DANRE
Sequence: MSTKQVTCRYFLHGVCREGSRCLFSHDLTTSKPSTICKYYQRGACAYGDRCRYDHIKPPGRGSGAPADHSNRSSSSAGASAPGPGPPANTSKHLKKPLVLRDKALCSDSRPRVFSAESSELNECWEQRDDGAQKPHSYLEAIRSGLDASAAAAATAGTFPELQQTSPQICPFLAAGQCQYGESCPYLHGEMCEICRQHVLHPHDPEQRAAHEKKCMVAFEMDMERAFAVQQSQDKVCKICLDVVYEKSSPSERRFGILSSCAHTYCLNCIRQWRCVEQLHNQIRKSCPECRVVSEFVIPSIYWVEDQEQKNLLIEEFKSGVSKKACKYFDQGRGTCPFGGKCFYMHAYADGRRAEPDKPRKQLSAEGNVRFQNSVRLWDFIEEREHRSVPQLEDEVNDLGELFMQLSGASDAPH
What is the function of this protein?
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity).  Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway (By similarity).  Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase makorin-2, RING-type E3 ubiquitin transferase makorin-2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MNMA_CLOAB
Sequence: MNKKVVIGMSGGVDSSVAAYLLKEQGYDVIGVTMKLTPDDAFYTEQEGGCCSLSAVEDARRVAYRIGIPFYVVNFTDIFKEKVIDYFTEEYLNGKTPNPCIACNKYIKFDALLKKAESLGADYIATGHYCRIVEENGRYVIRKSEDEKKDQTYVMYNMTQDQLKHTLMPCGDYKKDRIREIAREIGLNVFDKKDSEEICFIPDNDHGGFIKRECPKAVKTGNFVDKEGKVLGKHKGIIYYTIGQRKGLGIATGKRVFVTNIDAMKNQVVIGEEEEIFENELISFKNNFIPFDKLTEPMEVDAKIRYNAKASKATIYPVDDENVKVKFEKPQRAITKGQSVVFYDGDLLVGGGIIK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2A_BITGA
Sequence: DLTQFGNMINKMGQSVFDYIYYGCYCGWGGKGKPIDATDRCCFVHDCCYGKMGTYDTKWTSYNYEIQNGGIDCDEDPQKKELCECDRVAAICFANNRNTYNSNYFGHSSSKCTGTEQC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM1_SALSV
Sequence: MTLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQALADEVGAEVISLSDIDARLQDADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRQAAAVEAETIVEQEASEFMAWLRAQGASETIREYRSQSEQIRDELTTKALSALQQGGDAQAILQDLAWKLTNRLIHAPTKSLQQAARDGDDERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: UB2J1_HUMAN
Sequence: METRYNLKSPAVKRLMKEAAELKDPTDHYHAQPLEDNLFEWHFTVRGPPDSDFDGGVYHGRIVLPPEYPMKPPSIILLTANGRFEVGKKICLSISGHHPETWQPSWSIRTALLAIIGFMPTKGEGAIGSLDYTPEERRALAKKSQDFCCEGCGSAMKDVLLPLKSGSDSSQADQEAKELARQISFKAEVNSSGKTISESDLNHSFSLTDLQDDIPTTFQGATASTSYGLQNSSAASFHQPTQPVAKNTSMSPRQRRAQQQSQRRLSTSPDVIQGHQPRDNHTDHGGSAVLIVILTLALAALIFRRIYLANEYIFDFEL
What is the function of this protein?
(Microbial infection) Promotes Dengue virus RNA replication by negatively regulating IFN-beta signaling and mediating 'Lys-48'-linked ubiquitination on IRF3 (PubMed:30157886).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 J1, E2 ubiquitin-conjugating enzyme J1, Non-canonical ubiquitin-conjugating enzyme 1, NCUBE-1, Yeast ubiquitin-conjugating enzyme UBC6 homolog E, HsUBC6e.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Protein: AMY4_CAPCH
Sequence: TDVGFDGWR
What are the official names of this protein?
Alpha-amylase 4, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: BIOC_PAESJ
Sequence: MNNPKTAIQRQFNRSAAGSYDIHADVQRTMAAELAKSIIERNSRGKATEPKILEIGCGTGQFTELLLNQWPHVSITALDLAPAMIHTAEQRFKSRQSANIRFLQADVEIWAVEAPSDSFDLIVSNACFQWLSHPRQTISHLKRFLREGGSLVFTTFGPNTFLELHQAFAEVYHAYGMEPQRHGLSVLSTNQWEEVLAEAGFSTIYCQQDTQKETYASPRDFLRSIKSMGASHSEAIPIDGLSPRKLFNEMYKVYEEKFNMKDGIVATYEWLLIYAG
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: RL21_HALHL
Sequence: MYAVIRSGGKQYRVSEGDVLRVEKLPAEVGETVQFDDVLMVGSGSEVKIGTPHVEGGSVKAEVLEQDRHRKVEVTKFKRRQGYRRHHGHRQPYTQVKITGISAG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: FER_ALIAC
Sequence: PFVITSPCIGEKAADCVETCPVDAIHEGPDQYYIDPDLCIDCAACEPVCPVNAIYQEEFVPEDEKEFIEKNRNFFRNR
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
Protein: ACEA_ASPFU
Sequence: MGFLEDEDQKYWDDVQAVKAWWKDSRWRYTKRPYTAEQIVAKRGNLKIHYPSNDQSKKLWKILESNFEKKVASFTYGCLEPTMLTQMAKYLDTVYVSGWQSSSTASSTDEPSPDLADYPMNTVPNKVNQLFMAQLFHDRKQREERITTPKDQRSKLPNIDYLRPIIADADTGHGGLTAVMKLTKLFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRAQADIMGTDLLAIARTDSEAATLITSTIDHRDHAFIVGSTNPNLQPLNDLMLAGEQAGKTGEELQAIEDQWIAQAGLKLFDDAVVDTIKAGVHVNKDALIKEYLTAAKGKSNSEARAIAKGITGVDIYWDWDAPRTREGYYRYQGGTQCAINRAVAYAPFADLIWMESKLPDYAQAKEFADGVHAVWPEQKLAYNLSPSFNWKKAMPREEQETYIKRLGALGYAWQFITLAGLHTTALISDQFARAYAKQGMRAYGELVQEPEMEQGVDVVTHQKWSGANYVDNMLKMLTGGVSSTAAMGKGVTEDQFKH
What is the function of this protein?
Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle.  Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available.  Acts also on 2-methylisocitrate.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, Threo-D(S)-isocitrate glyoxylate-lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: TRUB_STRGC
Sequence: MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVLPIAVGKATRMVEFMQDEGKVYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDEAIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVKRPERQVTIYQFERTSPISYEGQLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGMRLGDALTLEQIAERVAEEDYSFLQPLELGIGDLLKVELSDEQVEDVRNGRFISLVSDEAELAGFYGEKLVTILEKRKDQFKPRKVFL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RL1_STACT
Sequence: MAKKGKKYLDAASKVDRNEHYSVEDAISLAKETSVANFDATVEVAFRLVIDTRKNDQQIRGAVVLPHGTGKTQRVLVFAKGDKASEAEAAGADYVGESEYATKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVKKAVEEIKAGKVEYRAEKAGIIHASIGKVSFSTEDLVENFNTLQDVIAKAKPASAKGTYFKSVAVTTTMGPGVKVDTSNFKL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.