PharMolix/UniProtQA huggingface dataset:
Protein: FDL22_ARATH
Sequence: MTKKVCSCINELPDDLILKILSFVSTKHVVVTSLLSKKWKSLWTRVPILKYDVRDHTRFERFLDKSLFSHQSHVLESLHVELSVTLWNKDIGPWIRTALHHHHCHLRELEIDACIVHTVLPPELFTCKTLVVLKLKGIVIDVEAPLTTVSLPSLKTLHIDHSSLFDFGSLQMLLSNCNFITDLMVIRESRFFFAEYDVSWCKTLMALKLEGLKDVISISSSSAVCLPLLKTLHVARMEDFNNDSFCRLLSNCPVLSDLTLEEKTSDVLLNLDIDMPYLQRLSIITRVDADSKHIFSLMKNYTRKLAIIAPSFKYFSIQELAYASRYRYIVRVRLGVPSKLEDASTFSRIVHLELSICSERSVEMLVDLLLCFTKLVVLKLEHVYLLTPLGRWEPPSLVPECLLSSLEALEWKGYTGRYGDKDLRSNRLKRT
What are the official names of this protein?
Putative F-box/FBD/LRR-repeat protein At3g56780.
Protein: RS191_ARATH
Sequence: MATGKTVKDVSPHDFVKAYASHLKRSGKIELPTWTDIVKTGKLKELAPYDPDWYYIRAASMARKVYLRGGLGVGAFRRIYGGSKRNGSRPPHFCKSSGGIARHILQQLETMNIVELDTKGGRRITSSGQRDLDQVAGRIAVEP
What are the official names of this protein?
40S ribosomal protein S19-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
Protein: QUEF_HALH5
Sequence: MTGRKEEELEGVTLLGNQGTTYTFDYNPDILEVFENKHQGRDYFVKFNCPEFTTLCPMTGQPDFATVYISYIPDVKMVESKSLKLYLFSFRNHGDFHEDAMNIIMNDLIKLMDPRYIEVWGKFTPRGGISIDPYTNYGRPGTKYEKMAEYRMMNHDLYPETVDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
Protein: NADK_STRP8
Sequence: MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSKKNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLRKDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGDGISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIELVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGEIDS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNC_XANCP
Sequence: MTRPQAILTDIEGTTSSISFVKDVLFPYARRAMPAYVREHGGHPQVRHWLNQVADEIGEDVPDEVLITTLQTWIDEDRKHTALKALQGMIWEDGYRTADFSAHIYTDAAIQLQAWHAEGIPLYVYSSGSVPAQKLFFAHSDAGDLSGLVSDWFDTEVGPKRESSSYRRIAERIGVPAPEILFLSDVIEELDAAKRAGMRTALLDRLEDYPTPRSADDVGSHQRVESFTQLVL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: PTH_KLEP3
Sequence: MTIKLIVGLANPGAEYAATRHNAGAWYVDLLADRHRAPLREESKFFGYTSRINLAGEDVRLLVPTTFMNLSGKAVAAMATFYRINPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRVGIGHPGDKNKVVGFVLGKPPASEQKLIDDAVDEAARCTEIWLKDGLTKATNRLHAFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFEC_YERPE
Sequence: MLELLLQPFNYNYMVKAIWVSAIVGAVCAFLSAYLMLKGWSLMGDALSHSVVPGVAGAYALGFPYAAGAFFTGMLAALAMTLVRHITRLREDAIIGFIFSTFFAVGLLIVSLNPTSVNVQSIIFGNILGIADEDVLQVEIIILVSFVILCLIWKDLLAVFFDESHAMSIGLSPLRLKILFFTLLSACTVAALQTVGAILVIAMVVTPGATAYLLTDRFGRLLIIAIAIGAITSAFGAYLSFYLDGATGGVIVTLQTLVFLPAFFFAPKHGLLATRYRTRLKRRHPPVHLPEDNL
What is the function of this protein?
Part of an ATP-driven transport system YfeABC for chelated iron.
What are the official names of this protein?
Chelated iron transport system membrane protein YfeC.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS3_RICPR
Sequence: MGQKVCAHGFRVGPTLIKDWDSILYAEKHYKTLFIQDLKIRDLINKWFNQAQISRVLIERPSNKSIIININAKKPNIIIGKNGTEIDKLKKAIENMTFLKEVYINIHEVRKFNIDAAIVAQTIAAQLEKRVSFRKAMKTAIQASFKQGGQGIRVSCSGRLGGAEIARTEWYIEGRMPLHTLRADIDYSTAEAITTYGVIGVKVWIYKGEYKENKRYN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RABL3_XENTR
Sequence: MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRLHEYREGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNAVNGIILVHDLTNKKSSQNLYRWSLEALNRDLQPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIPEAKRSEVLTRTAFLAEDFNAEEINLDCTNTRCLAAGSSNAVKLSRFFDKVIEKRYSREGNLIPGFSDRKRFAGGNFKSLHYD
What is the function of this protein?
Required for KRAS signaling regulation and modulation of cell proliferation (By similarity).  Regulator of KRAS prenylation, and probably prenylation of other small GTPases (By similarity).  Required for lymphocyte development and function (By similarity).  Not required for myeloid cell development (By similarity).
What are the official names of this protein?
Rab-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: CARP4_RHINI
Sequence: MKFTLISSCVALACMALAVEAAPSGKKINVPLSKNANYKPNAKRAIEKANAKYARFRSSSSSSSSSSCGSAGTESSGSVPVTDDGNDIEYYGEVTVGTPGIKLKLDFDTGSSDLWFASTLCTNCGSSQTKYDPSQSSTYAKDGRTWSISYGDGSSASGILGKDTVNLGGLKIKNQIIELAKREASSFSSGPSDGLLGLGFDSITTVSGVQTPMDNLISQGLISNPVFGVYLGKESNGGGGEYIFGGYDSSKFSGDLTTIAVDNSNGWYGITIDGASISGSQVSDSFSAILDTGTTLLILPSNVASSVAQAYNANDNGDGTYNINCDTSELQPLVFTIGGSTFEVPTDSLIFEQDGNTCVAGFGYGQDDFAIFGDVFLKNNYVVFNPQVPQVQIAPISN
What are the official names of this protein?
Rhizopuspepsin-4, Aspartate protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: GUAA_SHESW
Sequence: MSDIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIILAGGPESVTAENSPRAPEYVFNAGIPVLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIEMLTKSALFKDIEDAVNSEGKPLLDVWMSHGDKVSAIPEGFVAVAKTDTCPFAAMANEEKRFYGVQFHPEVTHTRQGMRMLSHFALDICGCAANWKPSSIIEDAIERLKKQIGDDEVILGLSGGVDSSVVAMLLHRAIGKKLTCVFVDNGLLRLNEAAQVMEMFGDHFGLNIIHVDAENRFLDAMKGVADPEAKRKIIGRVFVEIFDEESKKCANAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMALGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: CBP4_CHAGB
Sequence: MVKKPFNWWLWTKMLVAGGAIIVGGPALTRWVQPTDEELFQKYNPELQKRSLERRFERQQEFDDFVNRLKRDSKSDKPIWTVQAEAEKERVRQASIAESLKAAEELKARKEAMRREVGLPAESASSETTR
What is the function of this protein?
Essential for the assembly of ubiquinol-cytochrome c reductase.  It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
What are the official names of this protein?
Assembly factor CBP4, Cytochrome b mRNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the CBP4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: KATG_YERPN
Sequence: MLKKILPVLITLAIVHNTPTAWAAEAPKTDSFYLPKSLDLSPLRLHNIESNPYGKDFNYAQQFKTLDLEAVKKDIKTVLTTSQDWWPADYGNYGPFFIRMAWHGAGTYRIYDGRGGADGGQQRFEPLNSWPDNANLDKARRLLWPIKKKYGAKISWGDLMVLTGNVALESMGFKTLGFAGGREDDWQSDLVYWGAGNKMLSDNRDKNGKLPKPLAATQMGLIYVNPEGPNGKPDPVAAAKDIREAFARMAMNDEETVALIAGGHTFGKAHGAASPEKCLGAAPGEAGLEQQGLGWANKCGSGNGKDTITSGLEGAWTTDPTHFTMQYLSNLYKHEWVLTKSPAGAWQWKPKNAANVVPDATDPTKFHPLMMFTTDIALKVDPEYKKITTRFLENPEEFKMAFARAWFKLTHRDMGPAARYLGDEVPKETFIWQDPLPAANYKMIDSADISELKDKILKTGLSDTKLIKTAWASASTFRGTDFRGGDNGARIRLAPQKDWPVNDPAELHSVLAALMEVQNNFNKDRSDGKKVSLSDLIVLGGNAAIEDAAKKAGYSISIPFTPGRTDASQEETDVSSFAVLEPTADGFRNYYDAKRNTLSPIASLIDRANKLELTVPEMTVLIGGLRVLDVNSGGSKAGVLTNTPGQLNNNFFVNLLDMSTKWTKSPKAEGYFDGYDRKTGKLKWTASSVDLVFGSNPELRAVAEVYASDDAKEKFVHDFTKVWEKVMNLDRFDIKNN
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: PURA_ECOL5
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_SALDC
Sequence: MQQRRPVRRALLSVSDKAGIIEFAQALSARGVELLSTGGTARLLAEKGLAVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEQHHIAPIDMVVVNLYPFAETVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDANEGSLTLDTRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATAQQVQGKALSYNNIADTDAALECVKEFNEPACVIVKHANPCGVAVSTTILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSATEDALKITAAKQNVRVLTCGQWAQRVPGLDFKRVNGGLLVQDRDLGMVSEAELRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYAKENMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSAMASDAFFPFRDGIDAAAAVGVSCVIQPGGSIRDDEVIAAADEHGIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: HSLU_BUCSC
Sequence: MRHIAEAAWKVNESIENIGARRLYTVLEHLMEDISYNSCNNKNELVINIDEEYVSKHLDELILNNDLNRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity).
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ1_NOCFA
Sequence: MARDYYGLLGVARNATDQEIKRAYRKLARELHPDVNPDEAAQARFKEVSTAYEVLSDPEKRRIVDMGGDPLESGGGAGGFSGAGFGGLGDVFEAFFGGMSGAGGGQRKPRGRVQPGADSLLRTRLSLAECAVGVTKHLTVDTAVLCDACHGSGTHGNSKPVRCETCGGAGEVQSVQRSFLGQVLTSRPCPTCRGAGETIPDPCHKCGGDGRVRARREIAAPIPAGVANGMRVRLAAQGEVGPGGGPPGDLYVEIVEQPHDVFVRDGDDLHCTIRVPMVDAALGTTVVIDTILDGPTELTIPPGTQPGEVSVLRGHGMPKLRSGVRGDLLAHLDIVIPTKLDGKQTELLRKYKALRDRDRAEVMSAQSEHNSGLFARLRASFSGR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ 1.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIR15_ARATH
Sequence: MKSTLIIFFTLCLSMAVMARHESYYGNTKPAKLNEEKVTRVRFYLHDTLSGQNPTAVRIAHANLTGGSASPVGFGSLFVIDDPLTVGPEKHSKEIGNGQGMYVSGCKDLSKFTIVMYADLAFTAGKFNGSSISIFSRNPVAEEVGEREIAIVGGRGKFRMARGFVKVKTNKIDMKTGDAVLRYDATVYHY
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
What are the official names of this protein?
Dirigent protein 15, AtDIR15.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: KAD_MARMS
Sequence: MRVILLGAPGAGKGTQAQFITEEFGIPQISTGDMLRAAVKAGSEMGLKAKAVMDAGQLVSDDIIIGLVKERLTQDDCANGALFDGFPRTIPQADALKDAGVEIDYVVEIDVADEEIVKRMSGRRVHEASGRTYHLVYNPPKVEGKDDVTGEDLVQRADDTEETVRLRLGVYHDQTAPLIGYYQDWLKADSATAPKFVKVNGIGDLNEIKQSLLASLKA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_ECOK1
Sequence: MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGHRVTQLHYARKGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQRFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CHED_AGRRK
Sequence: MILEATARRVHIIQGEYKVIGDPEVVLATILGSCVAACLRDPVAGVGGMNHFLLPGMASSPTSGGDATRYGVHLMELLINGLLKQGARRDRLEAKVFGGAKTIATFSNVGEQNAAFAMQFLRDEGIPVVSSSTGGEHGRKVEYWPVSGRARQYPLTGAETQKTVALEQRPVAAPKPVDNAIEFF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: CLH1_CHEAL
Sequence: SEKITVFQKGNFQVTEXSSHFV
What is the function of this protein?
Catalyzes the hydrolysis of ester bond in chlorophyll to yield chlorophyllide and phytol.
What are the official names of this protein?
Chlorophyllase type 1, CaCLH1, Chlorophyll-chlorophyllido hydrolase 1, Chlase 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
Protein: Y1236_HAEIN
Sequence: MKKSKIAAGVVVALAAVWCTSAWFTGKKAEEEYLYQLEQLNQLFTKTEALEESKIFYKNIKFERGLFASHIQDQIEIHKANETIIIPLSSTLYHGPLPLDRVAKLNFVPAIFSSQTLLGKNATTQAFFDITESEKPLQLNFAMNYSLSGNAELKLASGQYHNEQSKTDFDWSNVVLNIDLNQNTPNNYVLSVDTFNSNAPNHAVSTASSIKIKDLVVQGSLQSTKWPFIYSGNINSKIGYFEQNTESAESGEKFSLIQKNSQANLTTQVEGDTVNIINKTNLDELHINGNNLGKVTNNVEFNHIDGNALQELLNILVAIGKADSECLYLKHWCKNYNKQAWPLRIISLKLSLPLFLFLMKKAKWHWI
What are the official names of this protein?
Uncharacterized protein HI_1236.
What is the protein family that this protein belongs to?
To E.coli YdgA and YihF.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LEPA_GEOUR
Sequence: MVLENIRNFSIIAHIDHGKSTLADRLLEYTGALSEREMQNQFLDKMDLERERGITIKAQAVRLNYRAANGKDYILNLIDTPGHVDFTYEVSRSLSACEGALLVVDASQGVEAQTLANVYLALENDLDVFPVLNKIDLPAADPERVKQEIEDIIGLDAHDAVLASAKEGIGTREILEEIVTKIPPPQGDSNKPLKALLFDSWYDQYQGVIVLVRILDGMVKKGDKIQLMSNRRNYEVLKVGVFSPAMCEVAALSAGEVGFIIAGIKDVQDAKVGDTITSLHNPCDGPLPGFKEVQPMVFSGLYPIDTSQYEQLRDALAKLKLNDSSFSYEPETSLALGFGFRCGFLGLLHMEIIQERLEREFNLDLITTAPTVVYKVHRLDGSIITIESANQLPPVQEIQYVEEPFILASIHVPNEFVGGILALCEEKRGVQREIKYLTPTRVMVIYELPLNEVVLDFYDRLKSITKGYASLDYEHLDYRRSNLERLNIMINGEVVDALSLIIHKDKAYFRGRDLVSKMKELIPRQMFEIAIQAAIGNKVIARETVKAMRKDVLAKCYGGDITRKRKLLEKQKEGKKRMKNVGNVELPQEAFLAILKVEG
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS4C_CLOAB
Sequence: MATMREPRFKLSRRLGVNIYGHPKAMKRFETTNTRKKKISDYGMHLIEKQKLKAYYGVLEKQFSRYVKAAMKNKEASGSSLLKILECRLDNVVYRIGFANSIRQARQMVSHGLILVNGKKLDIPSYEVQVGDVVSLKEKHRQNEMFSNNFMNLSTFNVPYIEKNPDEFSGKLLRLPNIDEIPIKVNEVAVIEFYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
Putative 30S ribosomal protein S4 C.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: SIPB_SALTY
Sequence: MVNDASSISRSGYTQNPRLAEAAFEGVRKNTDFLKAADKAFKDVVATKAGDLKAGTKSGESAINTVGLKPPTDAAREKLSSEGQLTLLLGKLMTLLGDVSLSQLESRLAVWQAMIESQKEMGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAATKKLTQAQNKLQSLDPADPGYAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQNQVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQEETRKAEETNRIMGCIGKVLGALLTIVSVVAAVFTGGASLALAAVGLAVMVADEIVKAATGVSFIQQALNPIMEHVLKPLMELIGKAITKALEGLGVDKKTAEMAGSIVGAIVAAIAMVAVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQLAQNGSKLFTQGMQRITSGLGNVGSKMGLQTNALSKELVGNTLNKVALGMEVTNTAAQSAGGVAEGVFIKNASEALADFMLARFAMDQIQQWLKQSVEIFGENQKVTAELQKAMSSAVQQNADASRFILRQSRA
What is the function of this protein?
Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane.  Along with SipC, is necessary for the transfer of other effector proteins into the host cell.  Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent).  The former is dependent of its membrane-fusion activity.  The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE.
What are the official names of this protein?
Cell invasion protein SipB, Effector protein SipB.
What is the protein family that this protein belongs to?
Belongs to the invasin protein B family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS), inserted into the phagosomal membrane and subsequently released into the host cell cytoplasm.
Protein: DAPAT_METMP
Sequence: MESYIQNLFAERIGGKSFGKEDVIYKFEKIKRAKQAAKLKYPDMELIDMGVGEPDEMADESVVEVLCEEAKKHVNRGYSDNGVQALKDEIPIYLEKIFGVKDLDPVNEVVHSIGSKPALAYITSVFINPGDVTLMTVPGYPVTATHTKWYGGSVETLPLLEKNNFLPELDAISKEVRENAKILYLNYPNNPTGAQATKKFYKEAVDFAFENDLIVIQDAAYAALTYGDKPLSFLSVKDAKEVGVEIHSFSKAYNMTGWRLAFVAGNELIVRGFAAVKDNYDSGQFIPIQKAGIHCLRHPEITEKTRAKYERRLSKMVKILKEAGFNAKMPGGTFYLYVKAPIGTKDGAKFANAEEFSQFMIKEKLISTVPWDDAGNFVRMAACFEAFKDGEISIEEEDRILNEVKRRLTEVEFVFE
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNA4_STRCO
Sequence: MSPGQKEALPVADRTPPLGVEELHALVAAGDIDTVVLAFPDMQGRLQGKRFAARFFLDEVLEHGTEGCNYLLAVDADMNTVDGYAMSSWDRGYGDFAMRADPATLRRLPWNEGTAMAVADLAWEDGSPVLAAPRQILRRQLERLAGHGYTAQVGTELEFIVFRDTYEHAWDANYRGLTPANQYNVDYSVLGTGRVEPLLRRIRNEMAGAGLTVESAKGECNPGQHEIAFRYDEALVTCDQHAVYKTGAKEIAAQEGMSLTFMAKYNELEGNSCHIHLSLADADGRNAMAEGGGMSDVMRHFLAGQLVALREFSLLYAPHINSYKRFQPGSFAPTAVAWGHDNRTCALRVVGHGRSLRFENRLPGGDVNPYLAVAGLVAAGLHGIEQRLELPEPCPGNAYTADFAHVPTTLREAAELWENSTLAKAAFGDEVVAHYRNMARVELDAFDAAVTDWELRRSFERM
What is the function of this protein?
Involved in the catabolism of monoamine ethanolamine.  Catalyzes the ATP-dependent gamma-glutamylation of ethanolamine.  No activity with polyamines (PubMed:31113893).  No complementation of the L-glutamine auxotrophy of an E. coli glnA mutant (PubMed:16932908).  Enables survival of S. coelicolor under high local environmental ethanolamine conditions.  May play a role during starvation conditions to limit intracellular ethanolamine concentration, which in excess is toxic to the cells (PubMed:31113893).
What are the official names of this protein?
Gamma-glutamylethanolamide synthetase GlnA4.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.