PharMolix/UniProtQA huggingface dataset:
Protein: IRS2A_XENLA
Sequence: MAGVLCPTEEDRSSRAALRMLPPQPCPDESGAYRRMSGPTLSQVQEEPAAEPPQPPASAAEDDVRKRGYLRKQKHGHKRYFVLRSQSHLGPARLEYYDNEKKFRSGQRSGCHPKRVIPLYLCFTVSRRADAKNKHLVALYTKDEYFAMAAENEQEQDGWYQALSELINESKGACLDTEELEENYGTLRPGTVFKEVWQVNVKPRGLGQAKNLSGVYRLCLSSKAVHLVKLNSDVACVHLLLMNIRRCGHSENYFFIEVGRSSSTGAGELWMQVDDCVVAQHMHETFLDTMKALKAYSEFRPRSKSQSSCTNPISFITTRRYLGNLPPSQTGLQRRARTESMVGTPPSAKNNSFRFRTSSEGEGTMTRPFRSVTGSLSHLNTARINLGKQEGAGRYVRAPFNSGYQSRSASLPVSHFPSATSPISVCSSSGHGSASETLTRPSSSSVCGSPSDGGFISSDEYGSSPGDLRYFRVRSNTPDSLGNTPPIQEENTLSDYMSMSTHSQPDSRDDYMEADKCFRKRTYSLTKHTNSASKQKSQTAISLGEDSEEINKQFAFAESPKLKDSSLVDDYSNGVIDSVCNQSRSKASDDGYMPMMPSNLYDSDYLPMAPKTVSAPKQINRCPSQADSKGYMMMFPINSSPVKNVFGGAATKSNLEKLSNGGYMDMSYGNSTKQIHDSNLNNNSRGLSSYFSLPRSFKSLTKQTTDQNEYVPMSSPGKLLHLGAENGVDVCKDGAVHDIAKIELKSSSSILDQQVKRPNKLTLGIRGSNTIPRMFDHSAPAEPTSPGEYINIDFSDKASSTPYSLSADGSPSSLGSSCDHRQSPLSDYMSVDIDVQSPKATAEQSNSLTDISLYACTVVSRMQPNAEYAKLPCGTACVSKTDNIMDDYTTMTFNMAMTPPRSFASETENGTKVDSPSSIVNRLCIGELTSLNSGFSLPNPLPEPIAGPKVIRADSQGRRRHSSETFASSSTVTTSSSCFTESGKRHSSASFDNVWLKPDENSCEQENKMSRHCSTGFQNGLNYISLSMHNGVCEPTSPDCHQHQNGSRNLESGGYVSIDFTRCDCLKCPTSRKD
What is the function of this protein?
Potentiates insulin signaling.
What are the official names of this protein?
Insulin receptor substrate 2-A, IRS-2-A, Insulin receptor substrate-undetermined designation, Insulin receptor substrate-unique, xIRS-u.
Protein: GLPB_ECOL6
Sequence: MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYTLLGPQRVLDLACQAQALIAESGAQLQGSVELAHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLIIDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFVVLASGSFFSGGLVAERDGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDEALRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHVAQQIAQRAGGQQ
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase.
Protein: UBIC_ECO45
Sequence: MSHPALTQLRALRYFTEIPALEPQLLDWLLLEDSMTKRFEQQGKTVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSGPELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_MYCLE
Sequence: MCPATVLDSILKGVRADVAAREACISLSEIKAAAAAAPAPLDAMAALREPGIGVIAEVKRASPSVGSLATIADPAKLAQAYEDGGARIISVLTEERRFNGSLDDLDAVRAAVSVPVLRKDFVVQPYQIHEARAHGADMLLLIVAALDQSALMSMLDRTESLGMIALVEVRTEQEADRALKAGAKVIGVNARDLMTLEVDRDCFSRIAPGLPSNVIRIAESGVRGPADLLAYAGAGADAVLVGEGLVKSGDPRAAVADLVTAGTHPSCPKPAR
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: AROK_MARMS
Sequence: MIKAPNIILVGPMGAGKTTIGRLISQSMGKEFYDLDKVIEDNAGADIPWIFEREGEDGFRKRETQALASIVESDTGDCVLATGGGIVMREENRDILRENALVVYLYASVAQQLYRTSKSTHRPLLQTGDPRATLKKLFEIRDPLYRDVATLVIETDSRHPRSVANKVLDAIKRHLKMEITVS
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBD42_ARATH
Sequence: MEEFDYISEFPDCLLTQILLNLPTKDSVKTSVLSKRWRNLWLNVPGLRLRTFDFPVFPYPYEEGFVRFMDRFMEFKCRSRLQKFMITYFEHNGYRDRLMELIGTLVDRGIQHLYVYMHTCNRVDFIRQNIYKSKTLVSLKLYNVELKNPEFVVSLPCLKILKLENIFHGEDGPLVVEKLISGCPVLEDLELIRPFDDNVGYGSLTAPKYSRNRDIIGDFLTVISSVRHTIICYSTSKMLYSYSKQLGPIPQFHNLYHLQARFSSSSLQLLPTFLESCPACPNLKNLIMEFPFEPKNIDFHKVPQCLISTLEYVQIEELILKEKSGIKLVDYFLENSAVLKKLTLSFTYHSKKKQDPESYKKLLTSTKLSPTCQIIID
What are the official names of this protein?
Putative FBD-associated F-box protein At5g44940.
Protein: SYV_CUTAK
Sequence: MTSQTFTTSSATPPTRGVVPDKPALEGLEVKWGKIWEDEQLYAFDATTVDSREQVFAIDTPPPTVSGHLHPGHVFSYTHTDTVARYQRMRGKKVFYPMGWDDNGLPTERRVQNYYGVRCDPSLPYDPDFTPPSKPNPKRQVPISRRNFVELCVELTAVDEKTFQDLWRAVGLSVDWNQLYTTISPESQRIAQLAFLRNYARGEAYLSDAPTLWDVTFSTAVAQAELEARDYPGAYHRLGFHRPNGEDVFIETTRPELLAACCALIAHPDDERYQHLFGTTVTTPLYGVEVPVLAHSAAEMDKGAGIAMCCTFGDLTDVAWWRELQLPTRTIIGRDGRILSETPQWIIDAGSAERYEAIAGKTTFTARKLVVEALVESGEMDGEPKPTQRKANFYEKGDKPLEIIGTRQWYIRNGGRDDDLRNALLERGRELEWVPEHMRHRYENWVEGLNGDWLISRQRFFGVPFPVWYPLGTDGEPDYDHPLLPDESALPVDPASQPPSGYQESQRGVAGGFIGDPDVMDTWATSSLTPQIVTGWERDADLFAKTFPMDFAPEAHDIIRTWVFSRVVRAHLENGMLPWKRAAISGFVTDPDRKKMSKSKGNTVVPTEIIDQFGADAVRWRAAMARPGMDSPFDKAQMKVGRRLAMKILNASKFVLGFGEGGQVCDITNPADLSMLAGLRELIAEATEAFDKFNYTAALEVCEQFFWTFCDDYLELIKERAYDSEGADNAGALSARTALRLALDVMLRLFAPFLPFVTEEVWSWWKDGSVHTSSWPTADEVPATGDVDLMSDVSAALVELRGVKSTHKVPMRTPILSARISAPASVIANLKAVESDLTKVSKTESLTFLTGGDKLVLEAELGEPPAKRKK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_ALIFM
Sequence: MEEGLQRCFVLHRRPYSESSLILDVFSEEYGRLSIISKGARSKRSNLKGVLQAFTPLLMKWSGKGSMRTLRQAETISLGIPLTGINLYSAMYINELLVRVVEQETPYPALFLDYLTALTELAQSTNPEPALRRFELALLSAMGYGVDFLHCAGSGEMVSPEMTYRYREQQGFMASIRHDPLMSFKGNELIAISERRFTTPEQLKAAKRFTRIALKPYLGGKPLKSRELFLPRTRSILK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: ARNB_SODGM
Sequence: MSEFLPFSRPALGDAELAAVGDVLRSGWITTGPKCAQLEQAFCQLTGNRHAIAVSSATGGMHVTLMALGLGPGDEVITPSLTWVSTLNMICLLGAEPIMIDVDRDTLMVTPALIEAAITPRTRAIVPVHYAGAPADIDAIRALGERYGIPVIEDAAHAAGTAYKGRHVGAAGTAIFSFHAIKNMTCAEGGMVVTDDDALAQRIRSLKFHGLAVDAFDRTMQGRAPQAEVITPGYKYNLADINAAIALVQLEKLTQHNARRAALAQRYLHGLADTPFLPLVPPAWEHHHAWHLFIIRVDERWCGIDRDGLMQALKECGIGTGLHFRAAHTQRYYRERFPDMVLPATEWNSVRMCSLPLFPSMNDDDVERVITALRAIAKV
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: CPXS2_TRIEI
Sequence: MNAMEFFQRSAGKWRSQRTTHHLAFRQAEIGHSDIEVINLDAKDPKILEICKMHEIDPSLAAGGAFVTWDGSMAWDKDDENHKGSTVFAIVPDSENPRSGRMLRERGYAEIIPVVGRFEMDDEDGLNLITEYETMSSIERFWFTSPNLRMRSSAVKRFGGFNTSTFCTEVRLVESNSDSQTETPHVDLEYYSAFGW
What is the function of this protein?
Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.
What are the official names of this protein?
Chromophore lyase CpcS/CpeS 2.
What is the protein family that this protein belongs to?
Belongs to the CpcS/CpeS biliprotein lyase family.
Protein: MUKB_HAEIN
Sequence: MSDVFELENEIELESDEVILENENVEEIVDAPIPFSMTTNNGIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAGFVTALIPDLTLLHFRNTTEAGSTGGSRDKGLHGKLRPGVCYAVLDTINSRHQRILVGVRLQQIAGRDKKVDLKTFSIQGVELSQNPTALFTETVGEHQARVLNLNELKDKIENIGAQFKQYHSITDYHGMMFDLGIIPKRLRSASDRSKFYKLIEASLYGGISSAITRSLRDYLLPENLGVRKAFQDMESALRENRMTLEAIKVTQSDRDLFKHLITETTNYVASDYMRNANERRGNIEAALESRREWYKAKAEQNLSQHRLVDLSREVAELAESERTLEVDHQSAVDHLNLVLNALRHQEKITRYQEDIAELTERLEEQKMVVEDANDALEESQAQFEQTEIEIDAVRSQLADYQQALDAQQTRALQYQQAIAALEKAKTLCGLADLSVKNVEDYHAEFDAHAESLTETVLELEHKMSISEAAKSQFDKAYQLVCKIAGEMPRSTAWESAKELLREYPSQKLQAQQTPQLRTKLHELEQRYAQQQSAVKLLNDFNQRANLSLQTAEELEDYHAEQEALIEDISARLSEQVENRSTLRQKRENLTALYDENARKAPAWLTAQAALERLEQQSGERFEHSQDVMNFMQSQLVKERELTMQRDQLEQKRLHLDEQISRLSQPDGSEDPRLNMLAERFGGVLLSELYDDVTIEDAPYFSALYGPSRHAIVVRDLNAVREQLAQLEDCPDDLYLIEGDPTAFDDSVLSAQELELGVVVQVSDRELRYSRFPEIPLFGCAAREKRLEELQIERDEVAEQHAQIAFDVQKCQRLHEHFSQFVGLHLALAFQPNPEALMSEINRERNEIDRELNQFNSGEQQLRIQLDNAKERLQLLNKLIPQLNVLADEDLIDRIEECREQLDIAEQDEYFIRQHGVTLSQLEPIANSLQSDPENYEGLKNELTQAIERQKQVQQRVFALADVVQRKPHFGYEDAGQAETSELNEKLRQRLEQMQAQRDTQREQVRQKQSQFAEYNRVLIQLQSSYDSKYQLLNELIGEISDLGVRADDGAEERARIRRDELHQQLSTSRQRRSYVEKQLTLIESEADNLNRLIRKTERDYKTQRELVVAAKVSWCVVLRLSRNSDMEKRLNRRELAYLSADELRSMSDKALGALRTAVADNEYLRDSLRVSEDSRKPENKVRFFIAVYQHLRERIRQDIIKTDDPIDAIEQMEIELSRLTAELTGREKKLAISSESVANIMRKTIQREQNRIRMLNQGLQNIAFGQVKSVRLVVNIRDTHAMLLDALSGQQDEYQDLFNDNRITFSEAMAKLYQRINPHIDMGQRTAQTIGEELLDYRNYLELEVEVFRGADGWLRAESGALSTGEAIGTGMSILLMVVQSWEEESRRIRGKDIVPCRLLFLDEAARLDGKSISTLFELCERLDMQLLIAAPENISPEKGTTYKLVRKIAGNQEYVHVVGLRGFGATE
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: DMB_HUMAN
Sequence: MITFLPLLLGLSLGCTGAGGFVAHVESTCLLDDAGTPKDFTYCISFNKDLLTCWDPEENKMAPCEFGVLNSLANVLSQHLNQKDTLMQRLRNGLQNCATHTQPFWGSLTNRTRPPSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKTAQPNGDWTYQTLSHLALTPSYGDTYTCVVEHTGAPEPILRDWTPGLSPMQTLKVSVSAVTLGLGLIIFSLGVISWRRAGHSSYTPLPGSNYSEGWHIS
What is the function of this protein?
Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides.  In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
What are the official names of this protein?
HLA class II histocompatibility antigen, DM beta chain, MHC class II antigen DMB, Really interesting new gene 7 protein.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Localizes to late endocytic compartment. Associates with lysosome membranes.
Protein: ACP_CELJU
Sequence: MSSIEERVKKIVAEQLGVKEEEVKNEASFVEDLGADSLDTVELVMALEEEFETEIPDEEAEKITTVQLAIDYINANLA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_GEODF
Sequence: MQKLIEKANTLMEALPYIRRFSGKTIVIKYGGHAMADEALKKSFALDVILLKYIGINTVIVHGGGPQINETLKRYGIVSQFVKGMRVTDEATMGVVEMVLTGQVNKEVVGYLNQHGGRAVGLSGKDGGLLLCKKLLQEVKNEQGVLETVDIGFVGDVVDVDSSILVTLEAGGFIPVIAPIGVGTGGESYNINADVVAGKVAAALKAEKLILLTDVSGVKDQGGNLLSSIALGDVPGLIEDGTITGGMIPKVTCCTDALTGGVHKAHIVDGRIEHAILLEIFTNVGIGTEIQA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_SALTI
Sequence: MRYTVALTGGIGSGKSTVADAFADLGITVIDADIIARQMVEPGQPALNAIAEHFGSELIAADGTLRRRALRERIFSHPEEKAWLNALLHPLIQQETQRQFQQATSPYVLWVVPLLVENRLYQKANRVLVVDVTPETQLIRTMQRDDVTREHVEHILAAQATREARLAVADDVIDNNGAPDAIASDVARLHASYLKLASQFVSQEKP
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_RUBXD
Sequence: MPTTNQLVRKERKRQTKKTATPALQGSPQRRGVCTRVSTTTPKKPNSALRKIARVRLTNGHEVTAYVPGEGHNLQEHSVVLVRGGRVKDLPGVRYKVVRGALDALGVEGRKQGRSKYGTKKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PEBPH_MIMIV
Sequence: MSNDFKVIINGQNIDNGQKIIFEKSQDVPKPIFDIGDNEYYTIAMVDPDAPSRENPIYKYFLHMLIVNNYQTLVSFQPPSPPKGSGYHRYFFFLLKQPKYIDQNIWKQQINNNSIRREKFNLSEFISDNKLTVIASTYFKTKR
What are the official names of this protein?
Phosphatidylethanolamine-binding protein homolog R644.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
What are the subcellular locations of this protein?
Virion.
Protein: PSBI_PROM0
Sequence: MLALKISVYTIVFFFVGIFLFGFLASDPTRTPNRKDLESPQD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: BGH3_BOVIN
Sequence: MALLGRLLPLALALALGPAATPAGPARSPYQLVLQHSRLRGRQHGPNVCAVQKLIGTNKKYFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGATTTQLYTDRTEKLRPEMEGPGSFTIFAPSNEAWSSLPAEVLDSLVSNVNIELLNALRYHMVDRRVLTDELKHGMALTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTVTNNIQQIIEIEDTFETLRAAVAASGLNTLLEGDGQYTLLAPTNEAFEKIPAETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSLETLEGTTLEVGCSGDMLTINGKPIISNKDVLATNGVIHFIDELLIPDSAKTLFELAADSDVSTAIDLFRQAGLSSHLSGNERLTLLAPMNSVFKDGTPPINARTKNLLLNHMIKDQLASKYLYHGQTLDTLGGRKLRVFVYRNSLCIENSCIAAHDKRGRYGTLFTMDRMLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVFAPTNEAFQALPRGELNKLMGNAKELANILKYHVGDEILVSGGIGALVRLKSLQGDKLEVSSKNNVVSVNKEPVAEVDIMATNGVVHAISSVLQPPANRPQERGDELADSALEIFKQASAFSRATQSSVKLAPVYQRLLERMKH
What is the function of this protein?
Plays a role in cell adhesion (By similarity).  May play a role in cell-collagen interactions (By similarity).
What are the official names of this protein?
Transforming growth factor-beta-induced protein ig-h3, Beta ig-h3, MP70, MP78.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Note=May be associated both with microfibrils and with the cell surface.
Protein: EFC1_PANTR
Sequence: MARPSPLCLLLLLTLLPPIVPSNSLLTEPPFRWRFYLHETWTQGNRLSTVTLATVDCQPHGCQAQVTFNFTSFKSVLRGWSNPTIGFVYDQTHSNCRDYWVDTNGGCPYAYCRMHVTQLDTAKKVQHTYRLTSDGRTTYFLTIPDPWDSRWVSGVTGRLYRWPTDSYPVGKLRIFLTYIRVIPQVLSNLQDQADNIKHQEEVINTLVQSHPKADMVTYDDKAEAGLFSWITLVRHGARLVNMAGLVNLSHCFLCTALSQPPLVAVPLPQAFNTSGNHTAHPSGVFSEQVPLFRDPLQPQFPFCYTTPNSSWCNQTYSGSLSNLSAPAGGYFWCNFTLTKHLNISSNNTLSRNLCLPISLVPRLTLYSEAELSSLVNPPMRQKRAVFPPLVIGVSLTSSLVASGLGTGAIVHFISSSQDLSIKLQMAIEASAESLASLQRQITSVAKVAMQNRRALDLLTADKGGTCMFLGEECCYYINESGLVETSLLTLDKIRDGLHRPSSTPNYGGGWWQSPLTTWIIPFISPILIICLLLLIAPCVLKFIKNRISEVSRVTVNQMLLHPYSRLPTSEDHYDVALTQQEAAR
What is the function of this protein?
TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain.  The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity).
What are the official names of this protein?
Endogenous retrovirus group FC1 Env polyprotein, CpzERV-Fc1env envelope protein, ERV-F(c)1 provirus ancestral Env polyprotein, Envelope polyprotein.
What is the protein family that this protein belongs to?
Belongs to the gamma type-C retroviral envelope protein family. HERV class-I F(c)1 env subfamily.
What are the subcellular locations of this protein?
Virion. SUBCELLULAR LOCATION: [Transmembrane protein]: Cell membrane; Single-pass membrane protein.
Protein: CCA_SALAR
Sequence: MKIYLVGGAVRDALLGLPVKDKDWVVVGATPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEADLQRRDLTINALARDDDGQIIDPWHGRRDLEARLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADDTLALMREMTAAGELEHLTPERVWKETENALTTRNPQVYFQVLRDCGALRVLFPEIDALFGVPAPAKWHPEIDTGVHTLMTLSMAAMLSPQLDVRFATLCHDLGKGLTPKNLWPRHHGHGPAGVKLVEQLCQRLRVPNDLRDLAKLVAEFHDLIHTFPILQPKTIVKLFDAIDAWRKPQRVEQIALTSEADVRGRTGFEASDYPQGRWLREAWQVAQAVPTKEVVEAGFKGIAIREELTKRRIAAVACWKEKRCPKPAN
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: LUXS_STRPQ
Sequence: MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLVQPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: FADS1_HUMAN
Sequence: MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
What is the function of this protein?
Does not exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity.
What are the official names of this protein?
Acyl-CoA (8-3)-desaturase, Delta(5) fatty acid desaturase, D5D, Delta(5) desaturase, Delta-5 desaturase, Fatty acid desaturase 1.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
Protein: DDN_MYCTU
Sequence: MPKSPPRFLNSPLSDFFIKWMSRINTWMYRRNDGEGLGGTFQKIPVALLTTTGRKTGQPRVNPLYFLRDGGRVIVAASKGGAEKNPMWYLNLKANPKVQVQIKKEVLDLTARDATDEERAEYWPQLVTMYPSYQDYQSWTDRTIPIVVCEP
What is the function of this protein?
Is involved in the bioreductive activation of bicyclic 4-nitroimidazole prodrugs such as PA-824 and delamanid developed for anti-tuberculosis therapy against both replicating and persistent bacteria.  It converts PA-824 into three primary metabolites resulting from reduction of the imidazole ring at C-3; the major one is the corresponding des-nitroimidazole that generates lethal reactive nitrogen species, including nitric oxide (NO), which appears to be responsible for the anaerobic killing activity.  Ddn uses the reduced F420 produced by FGD1 to activate PA-824.  Delamanid (OPC-67683) is also reduced by Ddn to its des-nitro form.
What are the official names of this protein?
Deazaflavin-dependent nitroreductase, F420H(2)-dependent quinone reductase Ddn, Fqr.
What is the protein family that this protein belongs to?
Belongs to the F420H(2)-dependent quinone reductase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: OMP2_CHLTR
Sequence: MSSKLVNYLRLTFLSFLGIASTSLDAMPAGNPAFPVIPGINIEQKNACSFDLCNSYDVLSALSGNLKLCFCGDYIFSEEAQVKDVPVVTSVTTAGVGPSPDITSTTKTRNFDLVNCNLNTNCVAVAFSLPDRSLSAIPLFDVSFEVKVGGLKQYYRLPMNAYRDFTSEPLNSESEVTDGMIEVQSNYGFVWDVSLKKVIWKDGVSFVGVGADYRHASCPIDYIIANSQANPEVFIADSDGKLNFKEWSVCVGLTTYVNDYVLPYLAFSIGSVSRQAPDDSFKKLEDRFTNLKFKVRKITSSHRGNICIGATNYVADNFFYNVEGRWGSQRAVNVSGGFQF
What are the official names of this protein?
Outer membrane protein B.
What is the protein family that this protein belongs to?
Belongs to the chlamydial OMP family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein. Note=Outer membrane of elementary body.
Protein: ATPD_SALPC
Sequence: MSEFVTVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENNRLNALPDVLEQFIHLRAASEATSEVEVTSATALSEEQLSKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVIDGSVRGRLERLADVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.