PharMolix/UniProtQA huggingface dataset:
Protein: VPS52_RAT
Sequence: MAAAATMAAAARELVLRAGASDMEEEEGPLGAGSGLQEPLQLGELDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISCEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKPMTNYQIPQTALLKYRFFYQFLLGNERATAKEVRDEYVETLSKIYLSYYRSYVGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKPSLRSRNTIFTLGTRGAVISPAELEAPILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFVVSGPAAHDLFHAVMGRTLSMTLKHLESYLADCYDAIAVFLCIHIVLRFRNIAAKRDVPALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPNERTLQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEFIEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKASVESLSQDVMRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHKPNF
What is the function of this protein?
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).  The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.  Acts as component of the EARP complex that is involved in endocytic recycling.  The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 52 homolog, SAC2 suppressor of actin mutations 2-like protein.
What is the protein family that this protein belongs to?
Belongs to the VPS52 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Recycling endosome. Note=Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex.
Protein: RS20_TRIV2
Sequence: MCANNKSALKRAQIAERNRVRNKTYKSSVKTLMKNYLSAVQAYAANPTPESKQEAQTRLAAAYSRIDKAVKRGILHPNNGARKKSRLASKLKPIEQTA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: KUP_BRUO2
Sequence: MSGELNGNDTSVQAAVSAGSVLEGAAFADEGEQHNESMKTLVLGALGVVYGDIGTSPIYAFREALHAAATNGILARSDILGVVSFIFWALTLVVTVKYVLFVLRADNNGEGGILSLMALVRGALKGRPDLILGVGICGAALFFGDAVITPAISVLSAMEGLEIVAPNLTPFVVPATVVILVTLFSVQKLGTGRVAIVFGPIMALWFVALGASGLWHIFDDPTVMAALNPYYAVRFLTVSPAVAFVTVGAVFLAMTGAEALYADLGHFGRKPIVRAWLWIVFPCLLLNYFGQAAFILSHGEAAALPFFQMIPSFALWPMVLLATAATVIASQAVITGAYSVARQAVQLNILPRLEIQHTSEKLHGQIYIPRVNLLLGLAVVILVLGFEKSSNLAAAYGIAVTGNMLVTTVLLYIVMTRIWNWRVSRALPIILGFLVIDMLFFSANIIKVHEGGWASIGIATVLVLIMWTWVRGTRHLFQKTRKAEVPLDLIVEQMAKRPPTIVPGTAVFLTGDPKSAPTALMHSLKHYKVLHENNVILTVVTASKPWVALADRARVSQYNERFMLVTLTFGYMQQPNIPRALGLCRRLGWKFDIMTTSFFLSRRSLKASVHSGMPLWQDKLFILLARTASDATEYFQIPTGRVVEIGTQVNI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANC_HYPNA
Sequence: MNSTKENPVEIIRTRNELQARVRAWKQAGETVGFVPTMGALHEGHLSLIEKAQEKVTRTVASIFVNPAQFAPGEDFDTYPRREGEDIAKLASVNCDAVYLPTVAEMYPEGSVTNVRVESLSDLLDGIYRPHFFYGVATVVARLFLHAQPDVAVFGEKDYQQLQVIRRMVRDLGFPIEIIGGATRRDADGLAQSSRNLYLSPDERRAAGAIYSAMHRAASRMALGTLPSEALKEAEGYILTAGFRKIDYVTLVDPATLQALPADTPLEDGAAARLLAAAWIGKTRLIDNISVTR
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_METM6
Sequence: MAKLKYKVEADPKNTARAMGRTLRISRKHAIELCRELSGMKLDAAVAYLNRVIALETPVPFKVHNKDLPHRKGKIGTHSGRFPQKASLEILQVLDNAKKNAEQKGLNTEKLRIKHISSNRGFTIKRYMPRAFGRASPKNQETIHIQVILEEFY
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SELA_ECO7I
Sequence: MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRDSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVTKAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDIPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSKKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2288_DEIRA
Sequence: MPLELVQGDIAHQPVDAVVTAANKQLMGGGGVDGVIHRAAGPRLLQAIRPIGGTPTGTAVITPAFDLERQGVKYVIHAVGPIWRGGQHGEAELLAGAYRESLRLGVENGCRSVAFPSISTGVYGYPLDRAAPIALATIQDFLRSHPDLSVRMVLYGADALHVFERALAQL
What are the official names of this protein?
Macro domain-containing protein DR_2288.
Protein: KPC1_LYTPI
Sequence: MSNSTLEMKGFARRGALRQKNVHEIKNHKFIPRFFKQPTFCSHCKDFIWGFGKQGFQCKVCSFVVHKRCHEFVTFQCPGLDPGVDSDDPRNKHKFKVHSYNSPTFCDHCGSLLYGLYHQGMKCGACDMNVHKRCQKSVPNLCGADHTERRGRIKVKAEVIGNKLQVTVAEAKNLIPMDPNGLSDPFVKLKLIPDQKRETKKKTRTIKGSLNPTWGESFDFNLEDTDRNRRLLVEVWDWDRATRNDFMGALSFGISELMKAGVDAWYKLLGQEEGEYYNVPAIAETESIDELTSNIKKLPMPTQEHVKPQNSNSMSGMGVVRASDFNFLSVLGKGSFGKVMLAEKKGTDELYAIKILKKDVIIQDDDVECTMTEKRVLGLPSKPAFLTALHSCFQTMDRLFFVMEFVNGGDLMFQIQKVGKFREPHAVFYAAEIAVGLFYLHSQGVIYRDLKLDNVLVDAEGHIKIADFGMCKEHMNEGDTTRTFCGTPDYIAPEIVAYQPYGKAVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHVPSYPKSMSRESVTMCKGFLTKHPGKRLGSGPTGEQDIREHQFFRRIDWEKLANREIQPPFVPSVRNPRAAENFDPYFTKIPCALTPTDKLIIMNIQDEFQGFTFVNEVFDGYVRSLPS
What is the function of this protein?
PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins.  PKC also serves as the receptor for phorbol esters, a class of tumor promoters (By similarity).
What are the official names of this protein?
Protein kinase C.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Protein: PSBB_LOTJA
Sequence: MGLPWYRVHTVVLNDPGRLLAVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWNITGGTITNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFSDERTGKPSLDLPKIFGIHLFLAGLACFGFGAFHVTGLYGPGIWVSDPYGLTGRVQPVNPAWGVEGFDPFVPGGVASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVGAGLAENQSFSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPIFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGSRTLFRDVFAGIDPDLDSQVEFGAFQKLGDPTTRRQVV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: E13L_TOBAC
Sequence: MALCIKNGFLAAALVLVGLLMCSIQMIGAQSIGVCYGKIANNLPSEQDVINLYKANGIRKMRIYYPDKNIFKALKGSNIEIILDVPNQDLEALANSSIANGWVQDNIRSHFPYVKFKYISIGNEVSPINNGQYSQFLLHAMENVYNALAASGLQDKIKVTTATYSGLLANTYPPKASIFRGEFNSFINPIIQFLAQNNLPLLANVYPYFVHISNTADVPLSYALFTQRGKNSAGYQNLFDAILDSMYFAVEKAGGPNVEIIVSESGWPSEGNSAATIENAQTYYRNLIDHVKRGAGTPKKPGKSIETYLFAMFDENVKKGEITEKHFGLFSPDQRAKYQLNFNSLMPIYIDISRVI
What is the function of this protein?
Is thought to be an important plant defense-related product against fungal pathogens.
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase, acidic isoform GL153, (1->3)-beta-glucan endohydrolase, (1->3)-beta-glucanase, Beta-1,3-endoglucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: LON_TRIL1
Sequence: MSKSDQEHTTTEPTIVAEEELRIPELLPLLPIRDVVVYPFMIIPLFVGREMSIKAVDQALAGDRMIMLATQHDIGDEDPTPDKIYNVGTVAMIMRMLKLPDGRVKILVQGLVKARIAEFVEFKPFHTVRIERLVEPVAVDNLETEALMRTVREQLAKIAELGKQISPEVMVILENITDPGSMADLIASNLGLKLSEAQMLLEIEDPVRRLTKVNDLLAREHEMLSVQAQIQNAAREEMGKNQKEYYLREQMKAIQQELGDHDGKEELEELRKAIETARMPENVEKEALKQLGRLERMHGDSGEAGVIRTYLDWLIEIPWSKTTRDSLDIIRAKKILDEDHSYLDKVKERILEFLAVRKLNKQMKGPILCFVGPPGVGKTSLGKSIARALNRKFVRISLGGVRDEAEIRGHRRTYLGALPGRIIQGMKQAGTRNPVFMLDELDKLGYDYKGDPSAALLEVLDPQQNNAFSDHYVNLPYDLSNVLFVATANHSDPIPSALFDRMEVINIPGYTEEEKLEIAIRYLVPRQMKDNGLKAKHIVFEEEALKEIIAKYTREAGLRNLEREIGNVCRKVARKIAEGHKRQIRVTPAAVATFLGAAKFLRDDEMDKNEVGVVNGLAWTSVGGEVLHIEATTMAGKGGMALTGQLGDVMKESVQAALAYIRSHGSEFHINPDWFQENEIHVHVPAGAVPKDGPSAGCAMATALISVLTKVPVKKDVAMTGEISLRGKVLPIGGLKEKILAAVRAGMKMVIIPEQNRKDLEDIPKAMQKKVKIVPVKEIDEVLKLALEKFPIPAPKGKAKPATPKVVVRPSKEISA
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BET2_NEOBT
Sequence: MMDLFKTDIMPDLQSSMMASIGSNWRFALFVAATLLTSYIVIVRPLKNVLFHPLRKYPGPKLFAGSSIPYGFWYMTGKWHTKIRQLHATYGPVVRIGPDELSYACPEAWEDIYGRYVPAKRKENPKPVWYCSPDAHDMVGASLGDHGRMRRVMTPGFTYSAMCKQEPLIKVHVDLFLEKLRGVCDDGNATVNMLEWFTYCTFDLIGDLSFGEPFGCLENSMLHPWLQLVFANIYVTHIILLCKRIPFFYLFLPIKTTLQLYRDFNRHVILLRQVVERRLSLTTPRNDFLDIMTSKKTSTLYLTNEEIFKNAILLTGGGAETTSSSLTGMAFILTTRPDVKKRIVEELHATFPNEEAINMRSVAQLTYTGAFIEEAMRYYPPGPNTMWRTTPAGGNTILGDYIPENTIIGIPHRVLYRSEAYWKHADEIHPERWLPDGQRPAEFDHDRREGFQPFSYGPRACIAMNLAYAEMRYILARFLWNFDIQETEQSKHWMDNQKAYLVWDKPGLFVRLKPVAKEEAQ
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of betaenones, phytotoxic polyketides involved in leaf spot disease in sugar beets (PubMed:25530455).  The first step of the pathway is the synthesis of dehydroprobetaenone I by the polyketide synthase bet1 and the enoyl reductase bet3 via condensation of one acetyl-CoA starter unit with 7 malonyl-CoA units and 5 methylations (PubMed:25530455).  The C-terminal reductase (R) domain of bet1 catalyzes the reductive release of the polyketide chain (PubMed:25530455).  Because bet1 lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase bet3 (PubMed:25530455).  The short-chain dehydrogenase/reductase bet4 then catalyzes reduction of dehydroprobetaenone I to probetaenone I (PubMed:25530455).  The cytochrome P450 monooxygenase bet2 catalyzes successive epoxidation, oxidation (resulting from epoxide opening) and hydroxylation to install a tertiary alcohol in the decaline ring to yield betaenone C from dehydroprobetaenone I and betaenone B from probetaenone I (PubMed:25530455).  The FAD-linked oxidoreductase (orf1) is probably responsible for the conversion of betaenone C to betaenone A via an intramolecular aldol reaction between C-1 and C-17 to form the bridged tricyclic system in betaenone A (By similarity).
What are the official names of this protein?
Cytochrome P450 monooxygenase bet2, Betaenone biosynthesis cluster protein 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PG079_VACCP
Sequence: DLARNLGLVDIDDEYDEDSDKEKPIFNV
What is the function of this protein?
Plays an essential role in viral DNA replication.  Binds to ssDNA with high affinity and localizes to cytoplasmic factories where nascent viral genomes accumulate.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.
What are the official names of this protein?
Truncated protein OPG079, Truncated protein I3.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG079 family.
Protein: CINA_BACAA
Sequence: MNAEIIAVGTELLLGQIANTNAQFLSEKLASIGINVYYHTVVGDNNKRLQQAIEVAEERADMLIFTGGLGPTKDDLTKETIASSLAEELVYDEKALASISDYFKRTGREFTENNKKQALVLDGATVFANDHGMAPGMGLNKNGKVYILLPGPPKEMKPMYVSYVEPFLRNFTTGENIYSRVLRFFGIGESQLEVKVQDLIDGQTNPTIAPLANDGEVTLRLTAKHQNVDEAEKLIQHVEDLILERVGGFFYGYDQEFLHDKAIVLLKKKGLTLACAESLTGGLFGNQVTESAGVSSVFKGGVICYHNDVKQHVLHVPEEVLFTDGAVSKECARYLAENVKELLEADIGISFTGVAGPDASEHKEPGTVFVGLAIKDEPTVVFPLNLSGSRQQIRERSAKYGFYHLYKKLEEI
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: LALBA_RABIT
Sequence: MMPLVPLLLVSIVFPGIQATQLTRCELTEKLKELDGYRDISMSEWICTLFHTSGLDTKITVNNNGSTEYGIFQISDKLWCVSKQNPQSKNICDTPCENFLDDNLTDDVKCAMKILDKEGIDHWLAHKPLCSENLEQWVCKK
What is the function of this protein?
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme.  This enables LS to synthesize lactose, the major carbohydrate component of milk.  In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
What are the official names of this protein?
Alpha-lactalbumin, Lactose synthase B protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CISY2_MYCTU
Sequence: MTVVPENFVPGLDGVVAFTTEIAEPDKDGGALRYRGVDIEDLVSQRVTFGDVWALLVDGNFGSGLPPAEPFPLPIHSGDVRVDVQAGLAMLAPIWGYAPLLDIDDATARQQLARASVMALSYVAQSARGIYQPAVPQRIIDECSTVTARFMTRWQGEPDPRHIEAIDAYWVSAAEHGMNASTFTARVIASTGADVAAALSGAIGAMSGPLHGGAPARVLPMLDEVERAGDARSVVKGILDRGEKLMGFGHRVYRAEDPRARVLRAAAERLGAPRYEVAVAVEQAALSELRERRPDRAIETNVEFWAAVVLDFARVPANMMPAMFTCGRTAGWCAHILEQKRLGKLVRPSAIYVGPGPRSPESVDGWERVLTTA
What are the official names of this protein?
Putative citrate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: SYCE2_MOUSE
Sequence: MERHGVAAPPVELKDQEPPAIVESGEHRQSENHEETPGSVAPSASCQLPGPFSSLDSSIETLKKKAQELIENINESRQKDHALMTNFRDSLKMKVSDLTEKLEERMYQVYSHHSKIIQERLQEFTQKMAKINHLEMELKQVCQTVETVYKDLCVQSEVPTCEEQNYKDGEC
What is the function of this protein?
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:15944401).  Requires SYCP1 in order to be incorporated into the central element (PubMed:15944401, PubMed:16968740).  May have a role in the synaptonemal complex assembly, stabilization and recombination (PubMed:15944401).
What are the official names of this protein?
Synaptonemal complex central element protein 2, Central element synaptonemal complex protein 1.
What is the protein family that this protein belongs to?
Belongs to the SYCE family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE1 in the central elements.
Protein: PDAD_HALSA
Sequence: MPRIRIAWGSGVAPTEMAAYDAALADANVHNYNLIRVSSVIPADATVSPVDTAPDLGPAGNTLTVVEARGQTAGPGQASAGLAWAPRDGAPGLFYEAADETTPDDVADRVTTGITAGMDVRDWDGVEPSVRTETVTADAGEHAAAVVIAAYGDSDPVFDQ
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase, PvlArgDC.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: DLTA_STRPM
Sequence: MIKDMIDSIEQFAQTQADFPVYDCLGEHRTYGQLKRDSDSIAAFIDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPSLIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPKGVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFALPKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELTVSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYIIDEDGKELASGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTEDNILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIVVKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINEVNNR
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSF_BRASB
Sequence: MIAMEGGAGNISTKMALEDTILTPRFYTTDFAAMDRLNVDLVRREWDAVMAELRADHNRKHFVRTPEFEKDLNELPEALRLEFKDFLVSSLTAEFSGCVLYAEIKKRITNPDIRELFSYMSRDEARHAGFINEILKDHGIGVDLGFLTKVKKYTYFKPKFIFYATYLSEKIGYARYITIYRQMERHPERQFHPIFKWFERWCNDEFRHGEAFALLMRADPKLLSGLNKLWIKFFLLAVFATMHVRDHMRPAFYEALGMPVDEYDMRVFRITSEISRQVFPVMLDIDNPRFWAGLNQLRKVSEAIADAKAQGGVMGAIKRAVLPLKAALTFGRLYMLPAKSNELPREIRLQPAW
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: IXTPA_LEPCP
Sequence: MRLVLASNNAKKLKELGTLLAPAGVELVTQGSLGIAEAEEPHHTFIENALAKARHAAAASGLPAIADDSGLCVDALGGQPGVQSAHYATLDPADIDGLAREALRERQDAANNRRLLSALDGQANRRARFVCTLVAIRSADDPEPLVALGRWEGELLTGLRGSGGFGYDPLLSIPALDATVAQLDAETKNRHSHRALAAEQMVALMRSAWHLA
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: GLYA_BORBU
Sequence: MRDDQIFNLIEKEKLREREHIELIASENFTSLEIRQAVGSILTNKYAEGYPLNRYYGGCSFIDEIETLAISRAKELFGAKYANVQPHSGSQANMAAIMALISPGDRILGMQLSHGGHLTHGSRVNFSGIFFNTYFYGVSRDSELIDYDEVLKIAKDCRPNLIIAGASSYSREIDFKKFREIADDVSAYLLCDIAHIAGLIVAGFHNSSIDVAHLTTSTTHKTLRGPRGGIILSGKDFDKLVNFNGKEKPLFNAVNSTVFPGTQGGPLVHVIAGKAIAFKEALQESFKEYIANVIKNTKVMAEYFKSEGFRIVSGGTDNHLFLVDLSSSDLTGADAEKLLESVNITLNKNAIPFDKKSPSLASGIRIGGAAITSRGLNESDSLNVAKFIVRALKAKSDIELKQIKKEVVRFIRDFDMP
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANM2_ECOL6
Sequence: MNKTITALAILMASFAANASVLPETPVPFKSGTGVIDNDTVYIGLGSAGTAWYKLDTQAKDKRWTALAAFPGGPRDQATSAFIDGNLYVFGGIGKNSEGLTQVFNDVHKYNPKTNSWVKLMSHAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNEAGKDSTAIDKINAYYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNKGDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLAPVASPDGVAGGFAGMSNDSLIFAGGAGFKGSRENYQNGKNYAHEGLKKSYSADIHLWHNGKWDKSGELSQGRAYGVSLLWNNSLLIIGGEAAGGKAVTDSVLISVKDNKVTVQN
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
What are the official names of this protein?
N-acetylneuraminate epimerase 2, N-acetylneuraminate mutarotase 2, Neu5Ac mutarotase 2, Sialic acid epimerase 2.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MNMG_HELPH
Sequence: MVKESDILVVGGGHAGIEASLIAAKMGARVHLITMLIDTIGLASCNPAIGGLGKGHLTKEVDVLGGAMGIITDNSGLQYRVLNASKGPAVRGTRAQIDMDTYRIFARNLVLNTPNLSVSQEMTESLILENDEVVGVTTNINNTYRAKKVIITTGTFLKGVVHIGEHQNQNGRFGENASNSLALNLRELGFKVDRLKTGTCPRVAGNSIDFEGLEEHFGDTNPPYFSYKTKDFNPTQLSCFITYTNPITHQIIRDNFHRAPLFSGQIEGIGPRYCPSIEDKINRFSEKERHQLFLEPQTIHKSEYYINGLSTSLPLDVQEKVIHSIKGLENALITRYGYAIEYDFIQPTELTHTLETKKIKGLYLAGQINGTTGYEEAAAQGLMAGINAVLALKNQAPFILKRNEAYIGVLIDDLVTKGTNEPYRMFTSRAEYRLLLREDNTLFRLGEHAYRLGLMEQDFYKELKKDQQAIQENLKRLKEYVLTPSKEVLKRLNELDENPINDKVDGISLLARDSFNAEKMRSFFSFLAPLNERVLEQIKIECKYNIYIEKQHENIAKMDSMLKVSIPKDFVFKGIPGLSLEAVEKLEKFRPKSLFEASEISGITPANLDVLHLYIHLRKNS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.