PharMolix/UniProtQA huggingface dataset:
Protein: ESAA_STAAN
Sequence: MKKKNWIYALIVTLIIIIAIVSMIFFVQTKYGDQSEKGSQSVSNKNNKIHIAIVNEDQPTTYNGKKVELGQAFIKRLANEKNYKFETVTRNVAESGLKNGGYQVMIVIPENFSKLAMQLDAKTPSKISLQYKTAVGQKEEVAKNTEKVVSNVLNDFNKNLVEIYLTSIIDNLHNAQKNVGAIMTREHGVNSKFSNYLLNPINDFPELFTDTLVNSISANKDITKWFQTYNKSLLSANSDTFRVNTDYNVSTLIEKQNSLFDEHNTAMDKMLQDYKSQKDSVELDNYINALKQMDSQIDQQSSMQDTGKEEYKQTVKENLDKLREIIQSQESPFSKGMIEDYRKQLTESLQDELANNKDLQDALNSIKMNNAQFAENLEKQLHDDIVKEPDTDTTFIYNMSKQDFIAAGLNEGEANKYEAIVKEAKRYKNEYNLKKPLAEHINLTDYDNQVAQDTSSLINDGVKVQRTETIKSNDINQLTVATDPHFNFEGDIKINGKKYDIKDQSVQLDTSNKEYKVEVNGVAKLKKDAEKDFLKDKTMHLQLLFGQANRQDEPNDKKATSVVDVTLNHNLDGRLSKDALSQQLSALSRFDAHYKMYTDTKGREDKPFDNKRLIDMMVDQVINDMESFKDDKVAVLHQIDSMEENSDKLIDDILNNKKNTTKNKEDISKLIDQLENVKKTFAEEPQEPKIDKGKNDEFNTMSSNLDKEISRISEKSTQLLSDTQESKTIADSVSGQLNQLDNNVNKLHATGRALGVRANDLNRQMAKNDKDNELFAKEFKKVLQNSKDGDRQNQALKAFMSNPVQKKNLENVLANNGNTEVISPTLFVLLMYLLSMITAYIFYSYERAKGQMNFIKDDYSSKNHLWNNVITSGVIGTTGLVEGLIVGLIAMNKFHVLAGYRAKFILMVILTMMVFVLINTYLLRQVKSIGMFLMIAALGLYFVAMNNLKAAGQGVTNKISPLSYIDNMFFNYLNAEHPIGLALVILTVLVIIGFVLNMFIKHFKKERLI
What is the function of this protein?
Component of the type VII secretion system (Ess).  Provides together with EssB and other components such as EssC and EssE a secretion platform across the cytoplasmic membrane in the host.
What are the official names of this protein?
Type VII secretion system accessory factor EsaA.
What is the protein family that this protein belongs to?
Belongs to the EsaA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRCB_THEP1
Sequence: MIELDYLTIAFGGAIGAVLRYLVSRTINSLLPFSYIPLGTIIVNSVGSFFLSFLMFAAIEKVPLSKEAILFFGTGLLGAFTTFSTFTYETLSLIEESPARGVAYALVNLLFAFTCAYFGMILGRGKV
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHS_HALMA
Sequence: MADLLSDAEISDRLPEEWTREDDEIVRVFEFDGYLDASGFLSAAAGLAEDAWHHPEMTIRWGEVEVRLTTHDAGGITENDIDLAERLNGIHD
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: COX2_BOSGA
Sequence: MAYPMQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLSFDSYMIPTSELKPGELRLLEVDNRVVLPMEMTIRMLVSSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKYFEKWSASML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HEMA_I57A5
Sequence: MAIIYLILLFTAVRGDQICIGYHANNSTEKVDTILERNVTVTHAKDILEKTHNGKLCKLNGIPPLELGDCSIAGWLLGNPECDRLLSVPEWSYIMEKENPRDGLCYPGSFNDYEELKHLLSSVKHFEKVKILPKDRWTQHTTTGGSRACAVSGNPSFFRNMVWLTEKGSNYPVAKGSYNNTSGEQMLIIWGVHHPNDEKEQRTLYQNVGTYVSVGTSTLNKRSTPDIATRPKVNGLGSRMEFSWTLLDMWDTINFESTGNLIAPEYGFKISKRGSSGIMKTEGTLENCETKCQTPLGAINTTLPFHNVHPLTIGECPKYVKSEKLVLATGLRNVPQIESRGLFGAIAGFIEGGWQGMIDGWYGYHHSNDQGSGYAADKESTQKAFDGITNKVNSVIEKMNTQFEAVGKEFSNLERRLENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRMQLRDNVKELGNGCFEFYHKCDDECMNSVKNGTYDYPKYEEESKLNRNEIKGVKLSSMGVYQILAIYATVAGSLSLAIMMAGISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RECF_PASMU
Sequence: MAISRLLIENFRNLTAVDLEFDHGFNFLVGNNGSGKTSLLEAIFYLGHGRSFKSAVSNRIISYEQPHFILHAKIQEQAHQWSVGLQKLRQGNSVVKINGEDGNKIADLAHLLPMQLITPEGLTLLNGGPVYRRAFLDWGLFHHHNHFHLAWVNLNRLLKQRNAALQQATHYQALEIWDRELVKLAHQVSEWRAQYAEALRPEIEQTCRLFLPELEISVSFHQGWEKDSDYADLLVRHFERDRAIGYTVSGPQKADFRFKANGLPVEDVLSRGQLKLLMCALRLAQGEHLMKQKERHCIFLIDDFASELDQYKRALLAERLKQSGSQVFVSAITETQLKQMQPQQHRTFRVEEGCIAPL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATD_HALLT
Sequence: MAKDVKPTRKNLMAIEDRIDLSERGHDTLEQKRDGLIMEFMDILDQAQDVRSDVSENYETAQRKIDMARAMEGDVAVRGAAAALKEHPEITTQSKNIMGVVVPQIESSKVKKSLDERGYGLLGSSARIDEAADAYEELLEKVILAAEVETAMKKMLTEIETTKRRVNALEFTLLPRLYENQEYIEQKLEEQEREEIFRLKKIKAKKEEEEKAEAAAEAAAVEDPEPAD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: AMPA_BURMS
Sequence: MDFSIKGCDWSKGTANGFLTGKSDCIVLGVFEAQTLSGAALDIDEATKGLVSRVIKAGDIDGKLGKTLFLHEVSGIGASRVLLVGLGRQDAFSQKAYGDAAKVAWRALLGTKVVQVTFTLAQLPVPERASDWGVRAAILALRNETYKFTQMKSKPDAGAPALKRVVFSVDPADDKAAKVAAKQAVALANGMDLTRDLGNLPGNVCTPTYLANTAKKIAKDWGLKVDVLGLKQIQALKMGSFLSVAKGSVEPPQFIVLQYRGAAAKAAPVVLVGKGITFDSGGISLKPGEGMDEMKYDMCGAGSVLGTMRAVAEMGLKVNVVAIVPTCENMPAGNANKPGDIVTSMKGLTIEVLNTDAEGRLILCDALTYAERFKPAAVIDVATLTGACIIALGHHNTGLFSKDDALAGELLDASREAGDPAWRLPLDDEYQDQLKSNFADLANIGGRPAGSVTAACFLSRFAENYPWAHLDIAGTAWKSGAAKGATGRPVPLLAQFLIDRAGA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPLA_ECOL5
Sequence: MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNSDLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEAEIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWMAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYAM1_BOVIN
Sequence: MLCPWKCQNAQRGLWNVFKLWVWIMLCCDFFAHHGTDCWTYHYSKRPMPWEKARAFCRENYTDLVAIQNKGEIEYLNKTLPFSRTYYWIGIRKVEGVWTWVGTNKSLTEEAKNWGAGEPNNRKSKEDCVEIYIKRNKDSGKWNDDACHKAKTALCYTASCKPWSCSGHGQCVEVINNYTCNCDLGYYGPECQFVTQCVPLEAPKLGTMACTHPLGNFSFMSQCAFNCSKGTDMIGVEETTCAPFGNWSSPEPTCRVIQCEPLTEPDLGTMDCNHPLVDFGFSSTCTFSCSEEAELTGEKKTICGLSGNWSSPSPRCQKINRTISINEESDYNPLFIPVAVMVTAFSGLAFIIWLARRLKRKSKKVSEKHG
What is the function of this protein?
Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells.  Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes.  Promotes initial tethering and rolling of leukocytes in endothelia.
What are the official names of this protein?
L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor.
What is the protein family that this protein belongs to?
Belongs to the selectin/LECAM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CCMM_SYNY3
Sequence: MLAKSLGWLLAVSRRNYCMGSRTALASRPWSKHLADPQIDPTAYVHSFANVVGDVRIQPGVSVAPGSSIRADEGTPFWIGGNVLIQHGVVIHGLETGRVLGDDDQEYSVWIGPGTCVAHLALVHGPVYLGANCFIGFRSTVLNARVGDGAVVMMHSLVQDVEIPPNKLVPSGAMITQQHQADSLPDVQAGDRHFVQQIAAMHGQSASPTQGTDPTVCVLPESLPAVTPVTETPYINSIDNMSINSDITNQIRSLLAQGYGIGAEHANERRFKTKSWQSCGTADGFRPDQVIATVEGWLQEFAGEYVRLIGIDQGAKRRVVEVIIQRPGDVPGSPSRGTTTTKALSSGGSGRSAVAHQTGNLAGDSANQLRALLHQGYKIGLEYASARRFKTGSWLTGGTIGSHREGEALQELNRFLADHTNEYVRIIGIDPAGKRRVAEIVVHRPNGNGNGKPSSSSSSVGYKSAPVSSAGGSSAGGLTPEVIATVRGLLANGHSIGTEHTDKRRFKAKSWDTCPTIDGGREAEVLAKLEACLADHAGEYVRIIGIDRVGKRRVLEQIIQRPGDNVVAGRSPSSSSASTSSSASSNGFGSGNGGGYSNSAVRLDNSVVTQVRSLLAQGYKIGTEHTDKRRFKAKSWQSCAPITSTHESEVLRALEGCLADHNGEYVRLLGIDPTAKRRVLETIIQRP
What is the function of this protein?
Beta-carboxysome assembly initiates when soluble RuBisCO is condensed into a liquid matrix in a pre-carboxysome by the RbcS-like domains of probably both forms of CcmM.  CcmN interacts with the N-terminus of full length CcmM, and then recruits the shell proteins (CcmK) via CcmN's encapsulation peptide.  CcmM73 also interacts with CcmK proteins and CcmL directly.  Shell formation requires CcmK proteins and CcmO.  CcmL caps the otherwise elongated carboxysome.  Once fully encapsulated carboxysomes are formed, they migrate within the cell probably via interactions with the cytoskeleton.
What are the official names of this protein?
Carboxysome assembly protein CcmM, CcmM73, M73, Carbon dioxide concentrating mechanism protein CcmM.
What is the protein family that this protein belongs to?
Belongs to the gamma-class carbonic anhydrase family.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes. Full length protein associates with the shell portion of carboxysomes, CcmM52 associates with both the soluble and shell portion of carboxysomes.
Protein: FIMV_PSEAE
Sequence: MVRLRTLVRAIAAASVLTSGMAHGLGLGEITLKSALNQPLDAEIELLEVRDLGSGEVIPSLASPEEFSKAGVDRLYYLTDLKFTPVVKPNGKSVIRVTSSKPVQEPYLNFLVQVLWPNGRLLREYTVLLDPPLYSPQAAASAPQAPVSAPRATGAPRAPQAPAPVRTTAPAGSDTYRTVSNDTLWEIAQRNRTDRVSVPQAMLAFQELNPGAFVDGNINRLKSGQVLRIPTEQQMLERSPREALSQVQAQNQSWRGSRNPAAGSAGARQLDATQRNAAGSAPSKVDATDNLRLVSGEGKASKGADKGGKGDSKAIADTLAVTKESLDSTRRENEELQSRMQDLQSQLDKLQKLIQLKDAQLAKLQGQLGAEGQGAAQPNAALPDASQPNAAAQAPAQPGTPAAAAPTPAPAGEAPAAPAQPPVAPPPAPAAEKPPAPAVPAPAPVQAAEQPAPSFLDELLANPLWLAVIGGSALLALLVLLMILSRRNAQKEKEEAQAFAADTGEEQEDALDLGKDGFDDLTLDEPEPQVAAVAPQVEKTTAQTSDALGEADIYIAYGRFNQAAELLQNAIYDEPQRTDLRLKLMEVYAEMGDREGFARQENELREIGGAQPQVEQLKSRYPAMVAVAAVAGLAGAKLAQDELDSFSLDDLSLDDSGHAAKPDAAGQDLDDAFDLSLDDLGGDDVQADLKSDSGALDDLTLDSDLDLAASTPADKPVDDLDFGLDFAELAETPSQPKHDDLGDFSLDLDAPEDKLSDDDFLLSLNDEVPAAAPADNEFTLDTEAAEEPALSLPDDFDLSLADEPTEPAAPEKGEDSFAAQLDEVSAQLDELASNLDEPKSATPSFSAEDAAVASALDGDADDDFDFLSGADEAATKLDLARAYIDMGDSEGARDILDEVLAEGNDSQQAEARELLERLA
What is the function of this protein?
Inner membrane hub protein that plays both cAMP-dependent and cAMP-independent roles in twitching motility (PubMed:27297880, PubMed:28583947).  Regulates intracellular cyclic AMP (cAMP) levels through the activation of adenylate cyclase CyaB (PubMed:20345659).  Plays an essential role in a number of virulence mechanisms including type IV pilus (T4P)-mediated assembly and twitching motility as well as cAMP-dependent virulence gene expression (PubMed:21097635, PubMed:10846211).  Mediates also type II secretion (T2S) of lipases and proteases (PubMed:21527471).  In addition, mediates the cAMP-independent localization of multiple T4P structural and regulatory components to the cell poles (PubMed:21527471, PubMed:27297880, PubMed:28583947).  This role in directing proteins to the cell pole is not restricted to type IV component and involves other proteins such as the diguanylate cyclase DgcP (By similarity).
What are the official names of this protein?
Motility hub protein FimV.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: BGL29_ARATH
Sequence: MNVQIFILLLIISWLTPKITSLPPESQVLDRSSFPDDFVFGTAISAFQSEGATSEGGKSPTIWDYFSHTFPERTNMQNADVAVDFYHRYKDDIKLIEELNVDAFRFSISWARLIPSGKVKDGVNKEGVQFYKALIDELIANGIQPSVTLYHWDHPQALEDEYGGFLNPQIIEDFRNFARVCFENFGDKVKMWTTINEPYVISVAGYDTGIKAVGRCSKWVNSRCQAGDSAIEPYIVSHHLLLSHAAAVQEFRNCNKTLQDGKIGIVISPWWLEPYDSTSSADKEAVERGLPLELEWHLNPVIYGDYPETMKKHVGNRLPAFTPEQSKMLINSSDFIGVNYYSIHFTAHLPHIDHTRPRFRTDHHFEKKLINRSNHETGPGDDRGKIHSHPEGLRRVLNYIKDKYNNPIVYVKENGIDHYDDGTKSRETILKDTFRISYHQDHLKQVHKAIIEDGCDVRGYYVWSLFDNFEWEHGYNSRFGMYYVDFKNNLQRYPKDSVNWFKKFLSRPVVRSEETEDEKVCNVSRKEEKINKALDVSEGFKTSVDSIVNLIKNGSRIEEEDDEEERDFCAFKNHNDQLGFFLKLQNSLGF
What are the official names of this protein?
Beta-glucosidase 29, AtBGLU29.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: CTPA_TETOB
Sequence: MHSRTNCLQTSVRAPQPHFRPFTAVKTCRQRCSTTAAAAKRDQAQEQQPWIQVGLGLAAAATAVAVGLGAAALPAQAVTSEQLLFLEAWRAVDRAYVDKSFNGQSWFKLRETYLKKEPMDRRAQTYDAIRKLLAVLDDPFTRFLEPSRLAALRRGTAGSVTGVGLEITYDGGSGKDVVVLTPAPGGPAEKAGARAGDVIVTVDGTAVKGLSLYDVSDLLQGEADSQVEVVLHAPGAPSNTRTLQLTRQKVTINPVTFTTCSNVAAAALPPGAAKQQLGYVRLATFNSNTTAAAQQAFTELSKQGVAGLVLDIRNNGGGLFPAGVNVARMLVDRGDLVLIADSQGIRDIYSADGNSIDSATPLVVLVNRGTASASEVLAGALKDSKRGLIAGERTFGKGLIQTVVDLSDGSGVAVTVARYQTPAGVDINKIGVSPDVQLDPEVLPTDLEGVCRVLGSDAAPRLFG
What is the function of this protein?
Protease involved in the C-terminal processing of the chloroplastic D1 protein of photosystem II.  This proteolytic processing is necessary to allow the light-driven assembly of the tetranuclear manganese cluster, which is responsible for photosynthetic water oxidation.
What are the official names of this protein?
C-terminal processing peptidase, chloroplastic, D1 C-terminal processing protease, Photosystem II D1 protein processing peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: ATPE_SINMW
Sequence: MAETFNFELVSPERLLVSETVTEVVIPATEGEMTVMANHAPTMTTVRPGVVAVKTAAGNTERYAVFGGFADILPTGCTLLAESAVHVDELDSTVLENRIEAARAELEGASDEKKTRLEQLVAELTKLGEIVIPA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KAD_MESHJ
Sequence: MKSNKKILFIGAPGSGKGTISKILVEKYKLVHISTGDLFRKKISEDSQFAAQIQNYLSSGSYVPDEITNKLVADFIKKIPKNQGYILDGYPRTLQQLEFMIKNGINLDCVFYLKIKNETIISRLSQRLFCQKCQKSYNLLLAKPKNELKCDLDSTDLITRNDDRPEIITHRIEKFNNSVIPIVEFFKKSGIIYYLDAEQTLEETVIEIEKWL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAN2_ASPTN
Sequence: MEADWDELSRIPVPPPSPHALPTVATTIAFDDVMELLWVGNEYGRITSFYGPELQRYTSVRAHPVAEGIVRQILFHERGVISLSSRSVHMITRRGLTQWHVAHEEMVDLRCMSFTAQLNRVIVAGCQKVMFTIDIDKGVIVDKLPTEYNYTMMKKSRYLCAATDTGSVNALSLSDFRVVKSWKAHGTAVNDMDARNDLLVTCGFSVRHLGSPIVDPLANVYDLKTLSPLPPIPFHAGAAYVRMHPKLSTTSFVASQTGQLQVVDLMNPNSINLRQANVSFMLGIDISPSGEALAINDAECMVHLWGSPAKIHFNEMSKEVELADVTHRPPPLDWSPDTPLNMIGMPYYHERLFSAWPSHLVFEVGSPPAPIDTGLIPYLRPAEIGHCAPNPKKTRRYQVENTRAVATTEPALIAPKFLSEKAREQSKKSDGSVAEAAGALAGAKLNGEAEDDPLLKYSNVEIKYSRFGVDDFDFRFYNQTNFSGLETHIANSFTNALLQLLKFIPLVRNVALHHAASSCVFENCLLCEMGYLFDMLEKANGQNCQATNLLKTFSSFREAASLGILEENLTNKSLSSAIQAVNRFFLGQIAHDFRTIMPNSDDLEQRLATIASESIQCRYCGNEIVRPGNSLVNELIYPNMDIKHTRRNPAFRFSNILRASIERETQNKGWCNYCRRYQPVGIRKSVHRMPLVMMLNAALNTPMARRLWAIPGWLPDEVGIVIDGGQTLCYEGEDLRMRVQANMPGLIVYELVGVVTEIDIPEHQKPHLVSFINVAISSPEPQPQNKWHLFNDFLVTEVDKDEALRFNQPWKVPCVLAFQVKDARHAMDDSWKDALDTTLLFRDWSLNGGRPVESRVTLSEDEKPTPGTPMALDTEFVDLEKAEIDVKADGSQEIVRPSKSGLARVSVLRGSGVREGVPFIDDYITIKEPIVDYVTQYSGIKPGDLDPRTSEHNLVPLKVAYKKLWLLLNLGCVFVGHGLASDFRKINIQVPKSQTVDTQYLFFHPGKSRRLSLRYLAWAVFKEYIQEEPADNNEGHDSIEDARMALRLWKKFLEYEDAGIVSQMLEEIFREGSKLGFRPPPRNGTAAVLSRPGTAVTMQNTNSGRNTPTVPDAAGAPAVPASAPTTPGRGFRRADALTPGDGTFSGPGAGDFFGGSPLK
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by xrn1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit pan2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_BACCZ
Sequence: MSLGVIAAAIAIGLSALGAGIGNGLIVSRTIEGVARQPELKGALQTIMFIGVALVEALPIIGVVIAFIVMNK
What is the function of this protein?
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient.  F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: G6PI_ECO57
Sequence: MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALM4_ARATH
Sequence: MADQLTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMAKKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVEEMIREADVDGDGQINYEEFVKIMMAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.  Activates MPK8 through direct binding and in an calcium-dependent manner.
What are the official names of this protein?
Calmodulin-4, CaM-4.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: JAMM1_THET2
Sequence: MAPPSVPIVYAGGRGGCPGGYHGLVLYVPRGLLEETRAHLLREAPKEGVGLWAGRREVERVIPLPNVHPSPLTAYLADPLALLKALKALEREGLSLLAIYHSHPKGPALPSPRDIKEARWRVPYVIFGTDGVRAFLLPEGQEVALVVL
What is the function of this protein?
Probable metalloprotease that cleaves the ubiquitin-like modifier protein TtuB from protein conjugates, hydrolyzing the isopeptide bond between a lysine residue of the target protein and the C-terminal glycine of the modifier protein.  Does not seem to work for all the TtuB conjugates.
What are the official names of this protein?
Probable TtuB-protein conjugate cleaving protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67B family.