PharMolix/UniProtQA huggingface dataset:
Protein: GLGC_STRZP
Sequence: MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALSNCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGTSHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEASRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDFGKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYSRNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAIIGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: Y7140_RICRS
Sequence: MDKFYNYNSSSHQALLSFKVKPNSKQNLISNFVIINNIQYLKLSIKAIPEQGKANSEIINYLAKEWKLSRSNIEIIKGHTHSLKTILIKNINEDYLNLIINSYIK
What are the official names of this protein?
UPF0235 protein A1G_07140.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: CAT4_PSEAE
Sequence: MGNYFESPFRGKLLSEQVSNPNIRVGRYSYYSGYYHGHSFDDCARYLMPDRDDVDKLVIGSFCSIGSGAAFIMAGNQGHRAEWASTFPFHFMHEEPVFAGAVNGYQPAGDTLIGHDVWIGTEAMFMPGVRVGHGAIIGSRALVTGDVEPYAIVGGNPARTIRKRFSDGDIQNLLEMAWWDWPLADIEAAMPLLCTGDIPALYRHWKQRQATA
What is the function of this protein?
This enzyme is an effector of chloramphenicol (Cm) resistance in bacteria.  Acetylates Cm but not 1-acetoxy-Cm.
What are the official names of this protein?
Chloramphenicol acetyltransferase, Xenobiotic acetyltransferase, XAT.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: MTM4_NEIGO
Sequence: MQFTSLEICAGAGGQALGLERAGFSHVALIEIEPSACQTLRLNRPDWNVIEGDVRLFQGEGYDGIDLLAGGVPCPPFSKAGKQLGKDDERDLFPEAIRLAKETDPKAIMLENVRGLLDPKFENYRNHITEQFAKLGYLGQWKLLYAADYGVSQLRPRVLFVALKNEYTNFFKWPEPNSEQPKTVGELLFDLMSENNWQGAHNWRLKAAQIAPTLVAVQKNTAVLTWDLHDPNAHGRSWVWMVQVCGIVRRLKTFTGMPRLTVRMTARIQGFPDDWQFFGKKTPMYRQIGNAFPPPVAEAVGRQIIKALKKEN
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-GCCGGC-3', methylates C-2 on both strands, and protects the DNA from cleavage by the NgoMIV endonuclease.
What are the official names of this protein?
Type II methyltransferase M.NgoMIV, M.NgoMIV, Cytosine-specific methyltransferase NgoMIV, DNA methylase M.NgoMI, M.NgoMI, Modification methylase NgoMIV.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: RR14_PSINU
Sequence: MAKKSLIEREKKRKKLVQEYNSIRKLLKEEIKKASSLKEKWEIHKKSQILPRNSAPTRLHRRCSLTGRSRSNYRDFGLCRHVLREMAHTCSLPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MAL_CANLF
Sequence: MAPAAASGGSSLPSGFSVFTTFPDLLFIFEFIFGGLVWILIASSLVPIPLVQGWVMFVSVFCFMATTALLVLYIIGAHGGENSWVTLDAAYHCIAALFYLSASVLEALATIGMQEGYTYKQYHENISAVVFSYVATLLYVVHAVFSLIRWKSS
What is the function of this protein?
Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane.  Could be involved in myelin biogenesis and/or myelin function.
What are the official names of this protein?
Myelin and lymphocyte protein, T-lymphocyte maturation-associated protein, VIP17 proteolipid.
What is the protein family that this protein belongs to?
Belongs to the MAL family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FRDD_ECO24
Sequence: MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGIVTI
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOB1_BURP1
Sequence: MSIEGVLKEGFVTTTADKLINWTRTGSLWPMTFGLACCAVEMMHAGAARYDLDRFGVVFRPSPRQSDVMIVAGTLCNKMAPALRRVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGVIQLQAKIRRTSTIARQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HISX_GEOMG
Sequence: MKFLDIRDTNFDMEFAAILARGEETGREVEQVVLDIIADVRARGDEALLEYTRRFDRLEADSVASLQVTEDEVDYAFARVKDEEIAALKLAVERVARFHEKQKQETWLSTGEPDILLGQMVTPLERVGIYVPGGKASYPSSVIMNAVPARVAGVGEVVMVAPTPGGEINPHVLVAARFSGVDRIFRLGGAQAVAALAYGTATVPKVDKITGPGNIYVATAKKLVFGQVGIDMIAGPSEILVINDGSGTPAHIAADLLSQAEHDELASSILITTDRGFGERVAAEVERQLAELSRETIARRSWETYGAVIVAGSLDEAIAFSNRIAPEHLELAVTNPFDVLPKIRNAGAIFLGHFTPEAAGDYLAGPNHTLPTGGTARFFSPLSVDDFVKKSSIVYFSESGLNRLGGGIVRIAELEGLEAHGRSVSVRLKGEGEARK
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: MBOA4_HUMAN
Sequence: MEWLWLFFLHPISFYQGAAFPFALLFNYLCIMDSFSTRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSLSEHVCKALPYFSYLLFFPALLGGSLCSFQRFQARVQGSSALHPRHSFWALSWRGLQILGLECLNVAVSRVVDAGAGLTDCQQFECIYVVWTTAGLFKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGYVPDADIWTLERTHRISVFSRKWNQSTARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYLIHSFANEFIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVYCILLLLLAKRKHKCN
What is the function of this protein?
Catalyzes ghrelin acylation at 'Ser-3' using preferentially octanoyl-CoA, hexanoyl-CoA and decanoyl-CoA as acyl-CoA donors leading to ghrelin activity (PubMed:24045953, PubMed:18443287, PubMed:25562443, PubMed:28134508).  In vitro uses also acyl-CoA donors of different lengths from short-chain (C2) to long-chain fatty acids (C16) knowing that acyl-CoA donors from butanoyl-CoA (C4) to dodecanoyl-CoA (C12) are more efficient compared to longer acyl-CoA donors, such as myristoyl-CoA (C14) and palmitoyl-CoA (C16) that are not efficient (PubMed:18443287).
What are the official names of this protein?
Ghrelin O-acyltransferase, Membrane-bound O-acyltransferase domain-containing protein 4, O-acyltransferase domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RPOA_BURM7
Sequence: MQTSLLKPKIIAVESLGENHAKVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVTIAGVVHEYSTLDGVQEDVVNLLLNLKGVVFKLHNRDEVTVTLRKEGEGVVTAGDIELAHDCEVINPNHVIAHLSKGGKLDVQIKVEKGRGYVPGNVRRYGDETAKIIGRIVLDASFSPVRRVSYTVESARVEQRTDLDKLVMNIETSGVITPEEAIRQSARILVDQLSVFAALEGTETAAEAPSRAPQIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SYGA_PSEF5
Sequence: MSQPTPAVRTFQDLILALQQYWAEQGCVVLQPYDMEVGAGTFHTATFLRAIGPETWNAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVLKPNPENFQELYLGSLKHVGLDPLVHDIRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGIECYPVTGEITYGLERLAMYLQGVDSVYDLVWADGPFGKVTYGDVFHQNEVEQSTYNFEHANVEKLFELFDFYESEAKRLIELDQPLPLPSYEMVLKASHTFNLLDARRAISVTARQQYILRVRTLARSVAQAYLLARAKLGFPMATPDLRDEVLAKLEAAQ
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKE_STAA3
Sequence: MIELKHVTFGYNKKQMVLQDINITIPDGENVGILGESGCGKSTLASLVLGLFKPVKGEIYLSDNAVLPIFQHPLTSFNPDWTIETSLKEALYYYRGLTDNTAQDQLLLQHLSTFELNAQLLTKLPSEVSGGQLQRFNVMRSLLAQPRVLICDEITSNLDVIAEQNVINILKAQTITNLNHFIVISHDLSVLQRLVNRIIVLKDGMIVDDFAIEELFNVDRHPYTKELVQAFSY
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import system ATP-binding protein NikE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MRAZ_ACIF5
Sequence: MFRGTHRHSLDSKGRMNVPARFRDWLNAHCDGQLVVTIDAQSQKGERCLVAYPLPTWEKVERRIAELPSNNPAARQFQRLFVGQSEELRLDAQARILLSPNLRKFAELDKELVLVGQIDKFEIWDAARWDACQETWLSGADGFACLGDLVL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TRPA_SINMW
Sequence: MTARMEQRFADVAAEGRPVLVTYFMGGDPDFDTSLAIMKALQQAGADIIELGVPFSDPMADGPAIQLAGQRALKAGQTLAKTLELARRFRADDQRTPIVLMGYYNPIYIYGVERFLTDALEAGVDGMIVVDLPPEMDDELCIPALAKGISFIRLATPTTDDRRLPKVLENTSGFVYYVSMTGITGSALPDTSLIAGAVARIKAHTSLPVCVGFGVKTADHARAIGATADGVVVGTAIVNQIASSLTEEGRATEATVPGVEALVRGLAAGVRAARLAAAE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: DHR21_ORYSJ
Sequence: MEHQGQHGHVTSRVDEYGNPVGTGAGHGQMGTAGMGTHGTTGGMGTHGTTGGMGTHGTTGTGGGQFQPMREEHKTGGVLQRSGSSSSSSSEDDGMGGRRKKGIKEKIKEKLPGGNKGEQQHAMGGTGGAYGQQGHGTGMTTGTTGAHGTTTTDTGEKKGIMDKIKEKLPGQH
What are the official names of this protein?
Water stress-inducible protein Rab21.
What is the protein family that this protein belongs to?
Belongs to the plant dehydrin family.
Protein: ATPA_NITEU
Sequence: MQLNPSEISELIKSKIEGLSVTSEFRTQGTIVSLTDGIVRVHGLSDVMQGEMLEFPGGTFGLALNLERDSVGAVILGAYEHLKEGDIVKCTSRILEVPVGEALLGRVVNALGQPIDGKGPIAAEGTEPIEKIAPGVVWRKSVDQPVQTGLKSIDSMVPVGRGQRELIIGDRQTGKTAVAIDAIINQKGEDVICIYVAIGQKASSIANVVRKLEEVGAMAYTIVVVASASESAAMQYIAPYSGCTMGEYFRDKGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEKATGGKVKGKTGSLTALPIIETQAGDVTAFVPTNVISITDGQIFLESDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGGIRLALAQYRELAAFAQFASDLDEATRKQLERGKMATELMKQSQYATLKVSEMALTLFALNKGYFDDVDIKRALAFESALKSHIRSHHGAILDKIEASKELDAETEKALEAAIQEFKQNGTY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: METAS_YERPN
Sequence: MPIRVPDELPAVSFLRNENVFVMASSRAKTQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRVDSRESKNTPTEHLNNFYCDFEDIQDQNFDGLIVTGAPLGLVDFCDVAYWPQIERIIAWAKEHVTSTLFVCWAVQAALNILYGIPKMTREVKLSGIYQHQTLEPLALLTRGFDETFLAPHSRYADFPVEVLQQYTDLDILVSSEEAGAYLFASKDKRVAFVTGHPEYDVDTLAGEYQRDLAAGLNPQVPLNYFPSDDASLRPKASWRSHGHLLFANWLNYYVYQITPFDLRHMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM24_YEAS2
Sequence: MISPRVNTRVWQRSISLLSPQAAKTESNVVTKERTYIENLSKDIATSRFRLVDENGKIASITVQPDIPICIKKDCLVSIHNLNHLSLSYKWLNFWSNLIKFRSFKSSLFHRIIGSSVLEILAAPNFQISRRPFDSSRSLSVLNLTGTKDWNVFGKDSIIAFEQNSSLEIKSPIFPSARSLVSNSSKSQLPRKFQILNGRGNVLVCGGGLVYSIELIDECDKILVNSRNILAINGQSQLDIANSVERQELHVEGAYVGDSSNDTVAPKFIKNQTLKSAYGHTVQFFKRMRSWIRNQYEKRYIYGVDSYFMKIKGPRTILIQTHEMTTSKDNILTKLTSKSHVKKSTVNDNGVNLEKQVANDVNSKIIELANRPSLFIATVSQDGRVDFQSTSKFT
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GLUQ_JANMA
Sequence: MTNKYIGRFAPSPSGPLHAGSLVAAMASYLDAKAHQGQWLVRIEDIDETRTVADATTAIMDALAVFGMQHDGEVVVQSQRKDLYQAAFERLKDLVYPCGCTRREIADSRLGVAADGAAIYPGTCRHGLAAGKTARTWRVRVPDANENNEAINFDDRWLGPLTQHLASEVGDFVLKRADGFWAYQLAVVVDDADQEVTHIVRGTDLLESTGRQIYLQRMLGFPTPHYMHVPVVLNDVGEKLSKQTGALALDLAHPMDELMKAARFLELSLPPVNSITEFWRVAIAAWARRFAQE
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: SELA_RHIME
Sequence: MSGPVDLRALPSVDQMLNAAAVSPLVEQHGRAVVTDELRKVLGEVRLAVRSGGALPGKDGIVAALLSRLDDRSRSNLRPLFNLTGTVLHTNLGRALLAQEAVDAAVDAMREAAALEFDLDSGGRGERDSHLRELLCELTGAEDATVVNNNAAAVLIALNSVGAGRQAIVSRGELIEIGGAFRMPDIMERAGVDLVEVGTTNRTHAKDYVKAIGPETALILKVHTSNYRIEGFTAEVPGAELAAIAHERGVVLLNDLGSGSLVDLSRYGLGREPTVREAVAEGADLVTFSGDKLLGGPQAGFIVGRRDLIAEINRNPLKRALRVDKIRIAATAATLKLYRDPDRLASRLPTLFMLSRVQAEVRAQAERLAPQVGAMLAPSGYAVEVCSCSSQIGSGALPVDTIPSAGLRIVGSSGSALEALAALFRSLSRPILGRLRDGALVLDLRCLSDEAEFLKTLSEGSGDAVA
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_XANOP
Sequence: MDAWPRCLERLEAEFPPEDVHTWLKPLQAEDRGDSIVLYAPNAFIVDQVRERYLPRIRELLAYFAGNGEVALAVGSRPRAPEPAPAPVAATIAPQAAPIAPFAGNLDSHYTFANFVEGRSNQLGLAAAIQAAQKPGDRAHNPLLLYGSTGLGKTHLMFAAGNALRQAKPAAKVMYLRSEQFFSAMIRALQDKAMDQFKRQFQQIDALLIDDIQFFAGKDRTQEEFFHTFNALFDGRQQIILTCDRYPREVEGLEPRLKSRLAWGLSVAIDPPDFETRAAIVLAKARERGAEIPDDVAFLIAKKMRSNVRDLEGALNTLVARANFTGRSITVEFAQETLRDLLRAQQQAIGIPNIQKTVADYYGLQMKDLLSKRRTRSLARPRQVAMALAKELTEHSLPEIGDAFAGRDHTTVLHACRQIRTLMEADGKLREDWEKLIRKLSE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_THEPX
Sequence: MVKVKICGLRRKEDIEYANELKPDYVGFVFAKSKRQIEVEQALDLISLLDKEIKTVGVFVNEPVENALKIAQTLNLDVLQFHGDETQDYIDNFKNFTVWKAIRIKDKEDLEKTKEFKVNSFVFDTLTKNEYGGTGKTFNWEVLKGFELNVPIILAGGLNENNVEEAIRIVNPYAVDVSSGVETEGYKDFKKMKSFIEKVRGIR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: SYP_MYCTO
Sequence: MITRMSELFLRTLRDDPADAEVASHKLLIRAGYIRPVAPGLYSWLPLGLRVLRNIERVIRDEMNAIGGQEILFPALLPRAPYETTNRWTQYGDSVFRLKDRRGNDYLLGPTHEELFTLTVKGEYSSYKDFPLTLYQIQTKYRDEARPRAGILRAREFVMKDSYSFDIDAAGLKAAYHAHREAYQRIFDRLQVRYVIVSAVSGAMGGSASEEFLAESPSGEDAFVRCLESGYAANVEAVVTARPDTLPIDGLPEAVVHDTGDTPTIASLVAWANEADLGRTVTAADTLKNVLIKVRQPGGDTELLAIGVPGDREVDDKRLGAALEPADYALLDDDDFAKHPFLVKGYIGPKALRENNVRYLVDPRIVDGTSWITGADQPGRHVVGLVAGRDFTADGTIEAAEVREGDPSPDGAGPLVMARGIEIGHIFQLGSKYTDAFTADVLGEDGKPVRLTMGSYGIGVSRLVAVVAEQHHDELGLRWPSTVAPFDVHLVIANKDAQARAGATALAADLDRLGVEVLLDDRQASPGVKFKDAELLGMPWIVVVGRGWADGVVELRDRFSGQTRELVAGASLATDIAAAVTG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSF1C_PONAB
Sequence: MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGTAPSDNRVTSFRDLIHDQDEDEEEEEGQRFYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNAVIVQRLT
What is the function of this protein?
Reduces the ATPase activity of VCP.  Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis.  May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER).  Inhibits the activity of CTSL (in vitro).  Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase.  Also, regulates spindle orientation during mitosis.
What are the official names of this protein?
NSFL1 cofactor p47, p97 cofactor p47.
What is the protein family that this protein belongs to?
Belongs to the NSFL1C family.
Protein: UXUA_YERPB
Sequence: MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWSVVESVPIHEDIKTHSGNYQQYIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELPDGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEAYFNAMTEADIAKLTGNIIAGLPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRPILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLRSTCREGNPKTFHEGGHLQGDVDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDLHKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPDLKQ
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: RS10_MARMM
Sequence: MERQNIRIRLKAFDHRVLDNSTREIVSTAKRTGANVRGPIPLPTRIEKFTVLRSPHIDKKSREQFEIRTHKRLLDIVDPTPQTVDALMKLDLSAGVDVEIKLGA
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MLES_LACPL
Sequence: MTKTASEILNNPFLNKGTAFTKEERQALGLTGTLPSKVQTIDEQATQAYAQFKSKPSRLEQRIFLMNLFNENRTLFFHLMDEHVVEFMPIVYDPVVADSIEQYNELFLDPQNAAFVSVDAPEDIEATLKNAADGRDIRLVVVTDAEGILGMGDWGVNGVDIAIGKLMVYTAAAGIDPSQVLPVSIDAGTNNQKLLDDPLYLGNRHKCVSGEQYYDVIDKFVAAEQQLFPDSLLHFEDFGRDNAQVILDKYKDQIATFNDDIQGTGMVVLAGILGALNISKESIKDQKILSFGAGTAGMGIANQILDELMQAGLTEEEAKQHFYAVDKQGLLFDDTEGLTPAQKAFTRKRSEFSNADELTNLEAVVKAVHPTVMIGTSTQPGTFTESIIKEMAAHTERPIIFPLSNPTKLAEAKAEDLIKWTDGRALVATGIPADDVEYKGVTYQIGQGNNALMYPGLGFGLIASTAKVLNAETLSAACHALGGIVDTSKPGAAVLPPVAKITEFSQKLAEVVAQSVIDQKLNKEPIADAKQAVADMKWVPEYRAISK
What is the function of this protein?
Involved in the malolactic fermentation (MLF) of wine, which results in a natural decrease in acidity and favorable changes in wine flavors.  Catalyzes the decarboxylation of L-malate to L-lactate.
What are the official names of this protein?
Malolactic enzyme, MLE.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: GPMA_BRUA1
Sequence: MSRTLVLVRHGQSEWNLKNLFTGWRDPGLTEQGHAEAKAAGQRLKAAGLKFDIAYTSALSRAQVTCQHILDELGQPGLETIRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDVPPPGGESLKDTGARVWPYYLHTIQPHVLREETVLVAAHGNSLRALIMALDGLTPEQILKQELNTGVPIIYRLNADSTVASKEILSA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RADA_IGNH4
Sequence: MGQVATEEKRPTSVAELPGVGPSTAAKLIDAGYGTIEALAVATPEELVAIGIPLTTAQKIIRAARQMLDIRFRTAKEVKLERMNLRKITTGSKNLDDLLGGGIETKTITEFFGEFGSGKSQLCHQASVNVQLPLEQGGLSEGDKVAKAVYVDTEGTFRWERIEQMAKCLGLDPDQVMDNIYYIRAVNSDHQMAIVEELFNLVPKENVKLIVVDSVTSHFRAEYPGRENLAVRQQKLNKHLHQLGKLAEVYNTAVIITNQVMARPDVFYGDPTQAVGGHVLYHAPGVRVQLKKARGNKRIARVVDAPHLPEAEAVFAITDCGIRDPED
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: RK12_CYACA
Sequence: MDKIDEIVEKIKLLSLLEASELVKRIEDTFQVNVSNIQPVTGLSSNLTTTQQTPESAEVKEKWDVILENVPADKKIAILKVVRSITGLGLKEAKEFVESVPKIIKQSISQADAEHIKQQIEDAGASVVLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.