PharMolix/UniProtQA huggingface dataset:
Protein: EYA1_CHICK
Sequence: RKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSRTNCVNILVTTTQLIPALAKVLLYGLGVVFPIENIYSATKIGKESCFERIIQRFGRKVV
What is the function of this protein?
Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for other transcription factors of this family.  Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1.  'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress.  Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis.  Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro).  Required for normal embryonic development of the skeleton, kidneys and ears (By similarity).
What are the official names of this protein?
Eyes absent homolog 1.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. EYA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Protein: HBOH_BURMS
Sequence: MTAIRGGSRRAPGLALALLGGVLLGACHGDENAQVNALPGFVSGSVRKTAYDGASDDLLTAGLGKTGLGSDTRPGFANPAQPSAAELRCLAIYSNYRALVDITPNGGYGRFWGPNVDLAGNDTLGEGKIAGTEYLAYSDDGSGRKNVTLLVQVPASFDPANPCIVTATASGSRGVYGAIAAAGEWGLKRGCAVAYNDKGGGNGAHEIGTGVVTLIDGTLATASSAGSSSLFTASESSSTLAAFNSAFPNRYAYKHAHSQQNPEQDWGRVTLQAVEFAYWALNEQFGPVVDGTRHGIRYRPGDITTIAASVSNGGGSALAAAEQDTRGWITAVVVGEPQINVRMTPGVTVEQGGAPVPSFGRPLADYATLANLLQPCAAAAVAATGAPYLSALPMGVTQSIRTQRCATLAAAGLVSGADTASQASDALAQLYAAGYLADSDLLQAPMWDSQAMPAIAVTYANAYTRSRVTDNLCNFSFATTNPVTGAVAAPAVSPMTNLFGAGNGVPPTNGINLVFNGASGGVDHRLATPDASFAGAFCLRQLWTANQLGIGTNVDAVRVAANLQHKPAIIVHGRSDALVPVNHASRAYVAQNSATEGRASQLSFYEVTNGQHFDAFLSVPGFDTRFVPVHYYDEQALNLMWNHLKSGAPLPPSQVIRTVPRGGVPGAAPALSTANLPPIVQSPGANAIAVNAGVIDVPL
What is the function of this protein?
Participates in the degradation of poly-3-hydroxybutyrate (PHB).  It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
What are the official names of this protein?
D-(-)-3-hydroxybutyrate oligomer hydrolase, 3HB-oligomer hydrolase, 3HBOH.
What is the protein family that this protein belongs to?
Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHR9_ARATH
Sequence: MSLLHTFKETLKPCGSFPSSSSLRVSSTQELEPSRKPPKSSLSQQLLRLDDSYFLPSKHESKISKTQVEDFDHNEDDHKRNIKFDEEEVDEDDERSIEFGRPGLSRAEFDYSGPYEPLMLSSIGEIPIIHVPASINCRLLEHQREGVKFMYNLYKNNHGGILGDDMGLGKTIQTIAFLAAVYGKDGDAGESCLLESDKGPVLIICPSSIIHNWESEFSRWASFFKVSVYHGSNRDMILEKLKARGVEVLVTSFDTFRIQGPVLSGINWEIVIADEAHRLKNEKSKLYEACLEIKTKKRIGLTGTVMQNKISELFNLFEWVAPGSLGTREHFRDFYDEPLKLGQRATAPERFVQIADKRKQHLGSLLRKYMLRRTKEETIGHLMMGKEDNVVFCQMSQLQRRVYQRMIQLPEIQCLVNKDNPCACGSPLKQSECCRRIVPDGTIWSYLHRDNHDGCDSCPFCLVLPCLMKLQQISNHLELIKPNPKDEPEKQKKDAEFVSTVFGTDIDLLGGISASKSFMDLSDVKHCGKMRALEKLMASWISKGDKILLFSYSVRMLDILEKFLIRKGYSFARLDGSTPTNLRQSLVDDFNASPSKQVFLISTKAGGLGLNLVSANRVVIFDPNWNPSHDLQAQDRSFRYGQKRHVVVFRLLSAGSLEELVYTRQVYKQQLSNIAVAGKMETRYFEGVQDCKEFQGELFGISNLFRDLSDKLFTSDIVELHRDSNIDENKKRSLLETGVSEDEKEEEVMCSYKPEMEKPILKDLGIVYAHRNEDIINIGETTTSTSQRLNGDGNSADRKKKKRKGCSEEEDMSSSNREQKREKYKMLAEFKGMEILEFSRWVLSASPFDREKLLQDFLERVK
What is the function of this protein?
May be involved in early DNA damage response (By similarity).  Probable chromatin remodeling factor.
What are the official names of this protein?
Switch 2, Protein CHROMATIN REMODELING 9, AtCHR9.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
Protein: NDHH_CRUWA
Sequence: MKRPVTGKDLMIVNMGPHHPSMHGVLRLIVTLDGEDVVDCEPILGYLHRGMEKIAENRAIIQYLPYVTRWDYLATMFTEAITVNGPEQLGNIQVPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFREREFIYDLFEAATGMRMMHNFFRIGGIAADLPYGWIDKCLDFCDYFLTEVVEYQKLITRNPIFLERVEGVGIIGGEEAINWGLSGPMLRASGIPWDLRKVDRYESYDEFEWEIQWQKQGDSLARYLVRLSEMTESIKIIQQALEGLPGGPYENLESRGFERKRNPEWNDFEYRFISKKPSPTFELSKQELYVRVEAPKGELGIFLIGDQSGFPWRWKIRPPGFINLQILPELVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: MIAA_VIBC1
Sequence: MTDKLPLALFLMGPTASGKTELAIRLRQRYPVEIISVDSALIYKDMNIGTAKPDERELSLAPHRLIDILDPSESYSAADFRRDALQAMDDIVAEGKIPLLVGGTMLYYKALLEGLSPLPAANPEIRQQIEQEALTKGWSVLHDELKEIDPVSAARIHPNDPQRLSRALEVFRISGKTLTELTQTKGDSLPYRVKQFAIAPKDRAELHRRIELRFDKMMEAGFEEEMKALYARKDLHPDLPSIRCVGYRQMWEYLDGDCTRDEAVFRGICATRQLAKRQITWLRSWNDLTWLDSDNIEQALETMSEAIASD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GLSA_PSEPF
Sequence: MQALLNEILDAVRPLIGQGKVADYIPALGTVPANQLGIAVYGNDGEMYCAGDAETPFSVQSISKVFSLVQAIEHSGEAIWERLGHEPSGQPFNSLVQLEFERGRPRNPFINAGALVICDINQSRFAAPALSMRDFVRRLSGNPQVMVDGKVADSEYQHRARNAAMAYLMQSFGNFHNDVEAVLRSYFSHCALRMNCIDLARAFCFLANDGFCKHSGEQILTRRQTQQVNSIMATSGLYDEAGNFAYRVGLPGKSGVGGGIVAVVPGQFTVCVWSPELNTAGNSLAGMAALEMLSSRIGWSVF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: SYM1_NEUCR
Sequence: MLSWYKAQLAARPLLTQAVTTSILFGVGDVAAQQLVDRRGLSNHDLTRTGRMVLYGGAVFGPAATTWFRFLQKRVVVPGSTNKTILARVAADQGLFAPTFIGIFLGSMAVLEGTDVKEKLQKNYWEALSTNWMVWPFVQMVNFKVVPLDHRVLFVNVISIGWNCYLSWLNGQ
What is the function of this protein?
May be involved in cellular response to stress.  Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity).
What are the official names of this protein?
Protein sym-1.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRFM_HUMAN
Sequence: MRGPSGALWLLLALRTVLGGMEVRWCATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVTIDTLKGVKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSESLCRLCRGDSSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGQALLSQDFELLCRDGSRADVTEWRQCHLARVPAHAVVVRADTDGGLIFRLLNEGQRLFSHEGSSFQMFSSEAYGQKDLLFKDSTSELVPIATQTYEAWLGHEYLHAMKGLLCDPNRLPPYLRWCVLSTPEIQKCGDMAVAFRRQRLKPEIQCVSAKSPQHCMERIQAEQVDAVTLSGEDIYTAGKTYGLVPAAGEHYAPEDSSNSYYVVAVVRRDSSHAFTLDELRGKRSCHAGFGSPAGWDVPVGALIQRGFIRPKDCDVLTAVSEFFNASCVPVNNPKNYPSSLCALCVGDEQGRNKCVGNSQERYYGYRGAFRCLVENAGDVAFVRHTTVFDNTNGHNSEPWAAELRSEDYELLCPNGARAEVSQFAACNLAQIPPHAVMVRPDTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSNYHGQDLLFKDATVRAVPVGEKTTYRGWLGLDYVAALEGMSSQQCSGAAAPAPGAPLLPLLLPALAARLLPPAL
What is the function of this protein?
Involved in iron cellular uptake.  Seems to be internalized and then recycled back to the cell membrane.  Binds a single atom of iron per subunit.  Could also bind zinc.
What are the official names of this protein?
Melanotransferrin, Melanoma-associated antigen p97.
What is the protein family that this protein belongs to?
Belongs to the transferrin family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Lipid-anchor, GPI- anchor.
Protein: SDRC_STAAW
Sequence: MNNKKTVTNRKGMIPNRLNKFSIRKYSVGTASILVGTTLIFGLSGHEAKAAEHTNGELNQSKNETTAPSENKTTEKVDSHQLKDNTQTATADQPKVTMSDSATFKETSSNMQSPQNATASQSTTQTSNVTTNDKSSTTYSNETDKSNLTQAKDVSATPKTTTIKPRTLNRMAVNTVAAPQQGTNVNDKVHFSNIDIAIDKGHLNKDTGKTEFWATSSDVLKLKANYTIDDSVKEGDTFTFKYGQYFRPGSVRLPSQTQNLYNAQGNIIAKGIYDSTTNTTTYTFTNYVDQYTNVSGSFEQVAFAKRENATTDKTAYKMEVSLGNDTYSEEIIVDYGNKKAQPLISSTNYINNEDLSRNMTAYVNQPKNTYTKQTFVTNLTGYKFNPNAKNFKIYEVTDQNQFVDSFTPDTSKLKDVTNQFNITYSNDNKTATVDLMNGQTSSNKQYIIQQVAYPDNTSTDNGKIDYTLDTDKTKYSWSNSYSNVNGSSTANGDQKKYNLGDYVWEDTNKDGKQDANEKGIKGVYVILKDSNGKELDRTTTDENGKYQFTGLSNGTYSVEFSTPAGYTPTTANAGTDDAVDSDGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQDSTEKGIKGVKVTLQNEKGEVIGTTETDENGKYRFDNLDSGKYKVIFEKPAGLTQTGTNTTEDDKDADGGEVDVTITDHDDFTLDNGYYEEETSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDTDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDADSDTDSDSDAGKHTPAKPMSTVKDQHKTAKALPETGSENNNSNNGTLFGGLFAALGSLLLFGRRKKQNK
What is the function of this protein?
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis.  Mediates interactions with components of the extracellular matrix such as host NRXN1 to promote bacterial adhesion.
What are the official names of this protein?
Serine-aspartate repeat-containing protein C.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: ACPS_LIMRD
Sequence: MIKGIGIDITEIERVKKAATAHSQFIQHVLTPTELEQYSQFSGQRSVEYLAGRWSLKESFAKAYGTGIGANLGFHDIEIIDNQYGAPIVTKSPYNGNAHASVSHTATLVMTEVILESENK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOSP_PI2HT
Sequence: MAEEPTYTTEQVDELIHAGLGTVDFFLSRPIDAQSSLGKGSIPPGVTAVLTSAAETKSKPVAAGPVKPRRKKVISNTTPYTIADNIPPEKLPINTPIPNPLLPLARPHGKMTDIDIVTGNITEGSYKGVELAKLGKQTLLTRFTSNEPVSSAGSAQDPNFKRGGELIEKEQEATIGENGVLHGSEIRSKSSSGVIPGVPQSRPQLASSPAHADPAPASAENVKEIIELLKGLDLRLQTVEGKVDKILATSATIINLKNEMTSLKASVATMEGMITTIKIMDPSTPTNVPVEEIRKSLHNVPVVIAGPTSGGFTAEQVILISMDELARPTLSSTKRITRKPESKKDLTGIKLTLMQLANDCISRPDTKTEFVTKIQAATTESQLNEIKRSIIRSAI
What is the function of this protein?
Essential component of the RNA polymerase and the nascent chain assembly complex.  Also required during RNA synthesis.
What are the official names of this protein?
Phosphoprotein, Protein P.
What is the protein family that this protein belongs to?
Belongs to the rubulavirus/avulavirus P protein family.
Protein: CYB_SIMAM
Sequence: MPHHYILTLFGLLPVATNISTWWNFGSMLLTCLALQVLTGFFLAVHYTANINLAFSSIIHITRDVPYGWMMQNLHAIGASMFFICIYIHIARGLYYGSYLNKETWMSGITLLITLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTSLTTWLWGGFAINDPTLTRFFALHFILPFAIISLSSLHIILLHEEGSSNPLGTNPDIDKIPFHPYHSYKDLLLLTLMILFLFIIVSFFPDIFNDPDNFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALVMSIMILFTIPFMHTAHLRPMTFRPLSQLMFWTLVSTFITITWAATKPVEPPYIMISQMTATLYFTFFLSIPILGWMENKMMNIP
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HRCA_LACGA
Sequence: MLTERQELILKTIIMDFTQSHEPVGSKTVMNQLPVKVSSATVRNEMAALEEKGLLEKTHSSSGRIPSTAGYRYYLDHLINPVKIPASVYNRIIYQLDQPFQQVNEIVQEAAKILSDLTNYTAFAAGPETRSVKVTGFRIVPLSSHQVMAILVTDDGNVKNQIYTLPHHTNGEEIEKAVRLINDQLVGKPLSSVNEVLLKRIADHLVAGGSAPEILDLLQDVIKDAASEQMYVDGQINLLSNYESDDLAKVKSLYKLIDQNDAISSLIGFNPKDEIKNDSKSKVQVKLGSELQSDLLEDYSLLTAQYSVGKYGKGTIALLGPTNMPYSQMIGLLEYFRNELAKKLLDYYGRFK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: TAA1_ARATH
Sequence: MVKLENSRKPEKISNKNIPMSDFVVNLDHGDPTAYEEYWRKMGDRCTVTIRGCDLMSYFSDMTNLCWFLEPELEDAIKDLHGVVGNAATEDRYIVVGTGSTQLCQAAVHALSSLARSQPVSVVAAAPFYSTYVEETTYVRSGMYKWEGDAWGFDKKGPYIELVTSPNNPDGTIRETVVNRPDDDEAKVIHDFAYYWPHYTPITRRQDHDIMLFTFSKITGHAGSRIGWALVKDKEVAKKMVEYIIVNSIGVSKESQVRTAKILNVLKETCKSESESENFFKYGREMMKNRWEKLREVVKESDAFTLPKYPEAFCNYFGKSLESYPAFAWLGTKEETDLVSELRRHKVMSRAGERCGSDKKHVRVSMLSREDVFNVFLERLANMKLIKSIDL
What is the function of this protein?
L-tryptophan aminotransferase involved in auxin (IAA) biosynthesis.  Can convert L-tryptophan and pyruvate to indole-3-pyruvic acid (IPA) and alanine.  Catalyzes the first step in IPA branch of the auxin biosynthetic pathway.  Required for auxin production to initiate multiple change in growth in response to environmental and developmental cues.  It is also active with phenylalanine, tyrosine, leucine, alanine, methionine and glutamine.  Both TAA1 and TAR2 are required for maintaining proper auxin levels in roots, while TAA1, TAR1 and TAR2 are required for proper embryo patterning.  Involved in the maintenance of the root stem cell niches and required for shade avoidance.
What are the official names of this protein?
L-tryptophan--pyruvate aminotransferase 1, Protein CYTOKININ INDUCED ROOT CURLING 1, Protein SHADE AVOIDANCE 3, Protein TRANSPORT INHIBITOR RESPONSE 2, Protein TRYPTOPHAN AMINOTRANSFERASE OF ARABIDOPSIS 1, Protein WEAK ETHYLENE INSENSITIVE 8, Tryptophan transaminase.
What is the protein family that this protein belongs to?
Belongs to the alliinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VGLU3_MOUSE
Sequence: MPFKAFDTFKEKILKPGKEGVKNAVGDSLGILQRKIDGTNEEEDAIELNEEGRPVQTSRAHRPVCDCSCCGIPKRYICDCSCCGIPKRYIIAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAASRVFGAAIFLTSTLNMFIPSAARVHYGCVMGVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWASVFYIYGMFGIIWYMFWLLQAYECPAAHPTISNAERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADPENLSEDKCGIIDQDELAEETELNHETFVSPRKKMSYGATTQNCEVQKTEWRQQRESAFDGEEPLSYQAEGDFSETS
What is the function of this protein?
Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, sodium and phosphate (PubMed:18215623, PubMed:18080752, PubMed:12384506).  At the synaptic vesicle membrane, mainly functions as an uniporter that mediates the uptake of L-glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells (PubMed:18215623, PubMed:18080752, PubMed:12384506).  The L-glutamate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane (PubMed:12384506).  In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane that affects the proton electrochemical gradient and promotes synaptic vesicles acidification (By similarity).  At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation (By similarity).  The symporter activity is electrogenic (By similarity).  Moreover, operates synergistically with SLC18A3/VACHT under a constant H(+) gradient, thereby allowing striatal vesicular acetylcholine uptake (PubMed:18278042).
What are the official names of this protein?
Vesicular glutamate transporter 3, VGluT3, Solute carrier family 17 member 8.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: SYC_DESHD
Sequence: MALRLFNTMSHQKEEFKPREEGKVGMYTCGPTVYNYFHVGNGRMLVVFDMIRRYLLYKGYDVTFVQNFTDIDDKIIKRGQEEGRDPLELAQDYIGEYFKDAAALNLMPASIHPKATDHIPEMIEIIKGLEEQGLAYAVDGDVYFAVDKLPAYGKLSGRTLEDMQAGARVEVGERKQNPMDFALWKNAKPGEPFWESPWGKGRPGWHIECSAMSLKYLGSGFDIHGGGGDLVFPHHENEIAQAEGYLHGETFARYWMHNAFLTINQQKMSKSLGNFFTVREILEHFPGEVIRFYLLGTHYRSPLDFDDENLQMAQKGLERLQTSIRLADEALGRQGQNSADAASGQKLRAAAEEARREFAEAMDDDFNSALAYASLFELGKAINAHVQAYPYSSEGLLKARATLWELADVLGFDLAKPANQAEAGNQKLDQVMELLLEVRAIARKKKDWEMSDLIRDRLKDLGIVLEDTPQGARWTLK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_MALP2
Sequence: MNLKDLIKLLEVKFPQIDSNEVESKITIYKNYLQQENKIHNLTRLDKEEEIYQKYFYESILNFHNDLFDNKNINLLDIGSGSGVPGIFLKILFPHINLYIVESNTKKVNFLNNLVDKLELENVFISNQRCEDYIKDKIEFFDLITCRAVAELRILLELSFPGLKINGIGFFLKSNNYLVELDNAKNISSKLKIEEEPKIETIEYDGKTFVSLKYIKKNKVNNIFPRTWKEILNNDKN
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL11B_YEAST
Sequence: MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSDDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQSNTHESSHASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSDSFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIQAYHKEVNQLLKMKTWDTDRYYDRKEIDPKRVINSMFIFNRKRGGTHKARFVARGDIQHPDTYDPGMQSNTVHHYALMTSLSLASDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSHLVQELNKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty1-LR1 Gag-Pol polyprotein, Gag-Pol-p199, TY1A-TY1B, Transposon Ty1 TYA-TYB polyprotein, p190.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NDK_CERS4
Sequence: MAIERTLSIIKPDATRRNLTGKINAKFEEAGLRIVAQKRIHLSLAQAQKFYGVHKDRPFFGELTEFMASEPVVVQVLEGEGAIAKNREVMGATNPANADAGTIRKEFALSVGENSVHGSDAPETAAEEIAFFFSGLELVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_YERPA
Sequence: MKKQFIQKQQQISFVKSFFSRQLEQQLGLIEVQAPILSRVGDGTQDNLSGSEKAVQVKVKSLPDSTFEVVHSLAKWKRKTLGRFDFGADQGVYTHMKALRPDEDRLSAIHSVYVDQWDWERVMGDGERNLAYLKSTVNKIYAAIKETEAAISAEFGVKPFLPDHIQFIHSESLRARFPDLDAKGRERAIAKELGAVFLIGIGGKLADGQSHDVRAPDYDDWTSPSAEGFSGLNGDIIVWNPILEDAFEISSMGIRVDAEALKRQLALTGDEDRLELEWHQSLLRGEMPQTIGGGIGQSRLVMLLLQKQHIGQVQCGVWGPEISEKVDGLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAP_STOVA
Sequence: KFCPEGKCV
What is the function of this protein?
Causes stimulation of sperm respiration and motility through intracellular alkalinization, transient elevations of cAMP, cGMP and calcium levels in sperm cells, and transient activation and subsequent inactivation of the membrane form of guanylate cyclase.
What are the official names of this protein?
Sperm-activating peptide, SAP.
Protein: RL29_LISIN
Sequence: MKANDIRDLSTTEIQDQEKALKEELFNLRFQLATGQLENTARIREVRKAIARMKTIVRERELA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RISB_CAMC1
Sequence: MKIIEGNLALKGNEKIAIINARFNHIITDRLVEGAKDAFLRHGGDEKNLTLVLVPGAFEIPMALEKVLASGKFDAVCCVGAVIRGATPHFDYVSAETTKGIANVTLKYAKPVTFGVLTVDSIEQAIERAGSKAGNKGFEAMTGVIEMLNLYKKLGE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.