PharMolix/UniProtQA huggingface dataset:
Protein: SC61A_NOTAN
Sequence: MGIKFLEFIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPSEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGTEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNILNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDATSGGPARAYPVAGLCYYLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEMGSMGALLF
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides.  May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins.  The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex.
What are the official names of this protein?
Protein transport protein Sec61 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes exclusively in granular structures in the endoplasmic reticulum (ER).
Protein: PURA_METVS
Sequence: MTCTIIVGGQWGDEGKGKVISYLCKKDNPSIIARGGVGPNAGHTVEVDGEKYGIRMVPTGFPNVNAKLAVGAGVLTDPEVLVREIEKLQKFNVGERIIIDYRCGVIESKHRDLDKSNEHLSKEIGSTGTGCGPANVDRAMRTLKLAKDVSELSKYLGDVSEAVNNAIESGDNVIIEGTQGSLLSLYYGSYPYVTSKDTNAASFAADVGLGPTKIDEVVAVFKSYPTRVGEGPFPTEMSLEEAEKLGVVEYGTVTGRRRRVGYFDFELAKKVCKLNGATQIAITCLDKYDPLCYGIIDYNELSEKGKAFIKEVEEKVGVRVTIISTGPELSQTIDIRNK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSA_SHEB2
Sequence: MNDAFSTAQHRLDALGLRCPEPVMMVRKTVRQMAAGETLLIIADDPATTRDIPSFCEFMDHTLIASETTQTPYQYLIKKGL
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2197_MYCTO
Sequence: MVSRYSAYRRGPDVISPDVIDRILVGACAAVWLVFTGVSVAAAVALMDLGRGFHEMAGNPHTTWVLYAVIVVSALVIVGAIPVLLRARRMAEAEPATRPTGASVRGGRSIGSGHPAKRAVAESAPVQHADAFEVAAEWSSEAVDRIWLRGTVVLTSAIGIALIAVAAATYLMAVGHDGPSWISYGLAGVVTAGMPVIEWLYARQLRRVVAPQSS
What are the official names of this protein?
Uncharacterized protein MT2253.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBT_PANGI
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GLPE_SALPB
Sequence: MEQFECITVEEAYQKLHQGAAVLVDIRDPQSYAMGHAPQAFHLTNDTLGAFMREHGFDTAVMVMCYHGNSSKGAAQYLLQQGYDAVYSIDGGFEAWHRRFPADVANGA
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UH105_NONUL
Sequence: MNKSILLLVTLLSLYSCTDTEKTPLEEKDVFNEDYIKTSMIKALEWQEAHPIFAIHPTDWTNGAYYTGVARAHHTTKNMMYMAALKNQAVANNWQPYTRLYHADDVAISYSYLYVAENEKRRNFSDLEPTKKFLDTHLYEDNAWKAGTNRSKEDKTILWWWCDALFMAPPVINLYAKQSEQPEYLDEMHKYYMETYNRLYDKEEKLFARDSRFVWDGDDEDKKEPNGEKVFWSRGNGWVIGGLALLLEDMPEDYKHRDFYVNLYKEMASRILEIQPEDGLWRTSLLSPESYDHGEVSGSAFHTFALAWGINKGLIDKKYTPAVKKAWKAMANCQHDDGRVGWVQNIGAFPEPASKDSYQNFGTGAFLLAGSEILKMR
What is the function of this protein?
Glucuronyl hydrolase involved in ulvan degradation.  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl).  Unsaturated 3S-rhamnoglycuronyl hydrolase works together with ulvan lyases to fully degrade the ulvan polymer, catalyzing specifically the cleavage of the unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) of deltaUA-Rha3S disaccharides and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides, the end products of the ulvan lyase reaction.  Also hydrolases deltaUA-Rha3S-IduA-Rha3S and deltaUA-Rha3S-GlcA-Rha3S tetrasaccharidestetrasaccharides.  Prefers tetrasaccharides over disaccharides and prefers an uronic residue at subsite +2.
What are the official names of this protein?
Unsaturated 3S-rhamnoglycuronyl hydrolase, Ulvan hydrolase, Unsaturated beta-glucuronyl hydrolase, UGL.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 105 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y1885_LISMF
Sequence: MGRSFYHFLMTYRDPKLTDQKTEFANNAYRDHSFPKQTRNYHILCDYLEFNAPYLPGMSIFDELWDAYLLDEEKNKH
What are the official names of this protein?
UPF0346 protein LMOf2365_1885.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: DMD_SACS2
Sequence: MLKSVTVSAPSNIAVVKYWGKRGDERLNLPLNNSLSITLDDQLSVITKVTLNDKNIVIVNDRILSEDEMKEYAGRVLDTFKKIVGKEFHVKVESKSKFPINAGLASSAAGIAALAFSLNELLELNLKSEELSKIARLGSGSACRSMFGGFVVWNKGEREDGEDSYCYQIFRHDYWSELVDIIPILSEKEKKISSRKGMIRSAETSELMECRLKYIEKTFNEVIEAIRNRDEKKFYYLMMRHSNSMHAVILDSWPSFFYLNDTSIRIMEWIHDYGKAGYTFDAGPNPHIFTTERNIGDILEFLKSLEIKRIIVSKVGDGPKVLSRE
What is the function of this protein?
Catalyzes the decarboxylation of mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP).  Functions in the mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
What are the official names of this protein?
Diphosphomevalonate decarboxylase, DMD.
What is the protein family that this protein belongs to?
Belongs to the diphosphomevalonate decarboxylase family.
Protein: WHIA_HELMI
Sequence: MSFSVETKEELARIQPRRRCCQLAELAALFRMDGSLQISGEQGLSLTVSTESASSARKIFRLIKAVFGVQTQILVRRKRRLKKSNVYVISLPARIGGRDVLQEMGITDSQGGFSFEPPSELLKRQCCRRAYLRGAFLGGGSVNSPEGTYHLEIITNDETHARILSELLHRFGLTAKVSQRKGWFIVYLKESEQIVEMLSIIGAHSALLNFENVRIVKGMRNQVNRLVNCETANLNKTVDAALRQTEMIRFVQNRIGFANLPSQLREVAELRLQYPDASLKELGQMLNPPVGKSGVNHRLRRLESLAEAFSRQGGVPRED
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: A62F_DROME
Sequence: MTDMWSLKICACLGLLLLFKPIDSMGWQGPKVDCTANGTQTECPVACPETCEYSGNGPCVKMCGAPCVCKPGYVINERIPACVLRSDCPKDVVRKEDMLLGVSNFKCFSRNYNCS
What is the function of this protein?
Responsible for physiological and behavioral changes in mated female flies.  May contribute to the toxicity of seminal fluid and the decreased life-span of mated females.  May also affect neuromuscular events after mating concerning sperm storage and egg release.
What are the official names of this protein?
Accessory gland protein Acp62F.
What are the subcellular locations of this protein?
Secreted.
Protein: CRCB2_MYCBO
Sequence: MTASTALTVAIWIGVMLIGGIGSVLRFLVDRSVARRLARTFPYGTLTVNITGAALLGFLAGLALPKDAALLAGTGFVGAYTTFSTWMLETQRLGEDRQMVSALANIVVSVVLGLAAALLGQWIAQI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPA1_ARATH
Sequence: MRESLVAILVTVISVLGAIHQVKSHEDQPLSGIAVHKITFGLNEKAYVKASPTVLGSNGQHSELVLVQYSSPKPSDDDWIGVFSPADFNASTCPGDNKMVQPPRLCSAPVKFQYANFSNPRYTNTGTGSLKLQLINQRSDFSFALFSGGLLNPKLVAISNKVAFENPNAPVYPRLALGKEWDEMTVTWTSGYGLNLAEPVVEWGVKGGERKLSPAGTLTFARNSMCGAPARTVGWRDPGYIHTAFLKELWPNSKYTYRVGHRLSNGALIWSKEYQFKSSPFPGQNSVQQVVIFGDMGKAEVDGSSEYNDFQRASLNTTKQLIKDLKKTDAVFHIGDICYANGYLSQWDQFIAQIEPIASTVPYMIASGNHERVWPNSGSFYEGLDSGGECGVPAETMFYVPAQNRAKVWYSSDYGMFRFCVADTEHDWREGTEQYNFIEHCLASVDRQKQPWLIFLAHRVLGYSSTYFYAEEGSFAEPMGRESLQKLWQKYKVDIAIYGHAHNYERTCPVYQSVCTSHEKSNYKAPLNGTIHIVAGGGGAGLAEFSDLQPNWSLFRDYDYGFLKLTAIDHSNLLFEYKKSSDGRVHDSFTISKDYRDILACAVDSCPATTLAS
What are the official names of this protein?
Probable inactive purple acid phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: FDL25_ARATH
Sequence: METRSVKRKKKKKEEEANWFIRVDRISNLPDSLNHQILLLLPLKSAAQASLLSKRWRSLFLSLPDLDFTSINDLKNPKSFSSNSIYKVLSLRSHRDSNNLRSLRFRVPVTFTSLNSLIRLAVTHQVQDLDIEVTTKDYFNFPRWIVTSQNLRALTLKSANLGFRLPPSSSARGGFQKLTSLSLSRVILHNQPCLSDFFTDPSFPLLEKLTLECCFGLKELKVSCRLLQEFSLKNSLQLEGLEVSGNKLQKLKVESCFYSYSEKSFVKINTPNLKTFLWNSNAVTTSVHFLDKLVCLRKAFVKVFWHHQDLNSQIQSLFTLLSGLCHSYKLQLGNQSVEILSSKKGLLKNHLLPFHNMRFLELQTRLNRHNVQTLSCLFKSCPMLNILTVKIIDDQTSERRQWNKDLWDMSNSEIQYWESQAYELESFLNHLEFVEIHGFVECENEMSLAIFLLRHGKALIKMTLRSSFLCRDSLRRQMIRSQLTGFSMASSKAKISFH
What are the official names of this protein?
Putative F-box/FBD/LRR-repeat protein At4g03220.
Protein: PITP2_DICDI
Sequence: MLIKEYRMVLPLTVEEYQIAQLYMVAKKSKESTKGGEGIEIIKNEPFDNEKGKGQYTEKIIYLANSLPRFAAAILPSSALKIEEKAWNAYPYCKTEYSCPFFGEKLVLSIESMHLPGRGEVENALKCDAETLKQRHVDFIDIANDQPKEYIKEEDPKIFKSVKTERGPLDDPKWRDKVEPVMTCYKLVHAEFKYWGFQTKVENVIQDTGVRDVLLKAHRALFCWIDEWFGLTIEDIRKIEEETKAELAKKLEENKAANK
What is the function of this protein?
Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.
What are the official names of this protein?
Phosphatidylinositol transfer protein 2, PtdIns transfer protein 2, DdPITP2.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: MSRB_ECO45
Sequence: MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPLSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: MNTP_ERWT9
Sequence: MNLYATLILAFAMSMDAFAAAICKGASLRRPTLKEALRTGLIFGVIEALTPLVGWAIGIAASQYVMAWDHWVAFGLLFILGARMIVEGIRKKECSLEDAPSRHGFWLLACTAVATSLDAMAVGVGLAFLQVNIVTTALAIGASTMIMATMGILLGRFLGPVMGKWAEIFGGVVLIGIGSSILVEHLGLLG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SIP5_CHAGB
Sequence: MGNSNTKESRAGDGSSRAHHGDPGSASLQSDRVSSRRNRVSRGDLGGILGLGTGASQSEPPYERRETKQEREARRLERERVARIAERERSMKEEHVDGGYLVTMGTYTSPEDFNKPIVRQLQIERKVAPFWRGLNDFDDQWTEPQIIAAARGLPVPPADQIPPEDLIPRPLPANPRTEGSSNLDNLTIPITGRSPSTASEHASSNPGSALPSPVSAQAPRANSPFKPRGKAIAAVLGGGGSRNGSTTELMPREINLPHDPFVNGQPLEVFLYKNATECPICFLTFPPYLNHTRCCDQPICSECFVQIKRPDPHFPEGHNENDPNHNPEETAGLLVSEPACCPYCTQPDFGVTYEPPPFRRGLSYSISLTAVGAASAAMSSSSSVNSASLSPTNASPSNGTGRRRNQSVSASSPSVILTDRIRPEWATKLQAARAHLARRAAAATALHTAAFIVGGSENRAFRSRFGRRNNGGSGSALPSPGGVNHGEGENGDSGSGTPSQNDMDQNSRGDPGRGRSGGNHRDRLEDLEEMMLAEAVRLSLAAEEERKRKVSKEERKEAKKREKEERKAAKAAAKQVGPYEGASGRSGHSSASGSTLSLPGFGFGRKRGNSAASNLRIEASVASAIATTESPEANPKEKGKGVDRAVSTHAEGAPATATDPAVLGGSASTSSPRPVPHLPAGPSHLRQMSNASSVTSSILDSRHGSYTSPTHLQDPRSSGLSLGSRSGASEDGGDADRDRDPCASTEPMFNFRSLAQVVGVSLDGENAGRRLSLIEAERRARESGETGSQDSADFGEVETIKTDTATDHADVKPQAEASGSLSVDTAMGRHIKGSPIAQNGSGEVESDSLSPPTVTITLETPATASANDELKQLGSEAAVEPVHRLTE
What is the function of this protein?
May negatively regulate the SNF1 kinase.
What are the official names of this protein?
Protein SIP5.
What is the protein family that this protein belongs to?
Belongs to the SIP5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIS11_ASPCL
Sequence: MSQLLTTRQAEELHKSIIAYLASVNLSESATTLRAELGDAVTIDDATIKKYEGLLEKKWTSVVRLQKKIMDLESRCAALQSELDSATPTSLLRKNQDPTAWLPRAPPRHTLESHRSPVTCVAFHPVFSSLASGSDDTTIKIWDWELGELERTVKGHTKAVLDVDYGGPRGGTLLASCSSDLTIKLWDPSDDYKNIRTLPGHDHSVSSVRFIPSGAAGSPMSGNLLVSASRDKTLRIWDVTTGYCVKTLSGHVDWVRAVAPSIDGRFLFAAGDDRIPRLWDLSAAETRSTFLGHEHVIECVAIAPAASYPHLAVLSGLKKPPSASSSAEFFATGSRDKTIRLWDSRGNLIKTLVGHDNWVRALAFHPGGKYLLSVSDDKTIRCWDLTQECKCVRTIADTHEHFVTCLRWAPPLIKDSGANGDAGANGTPAATTTSNGARQDPNAANKISIRCVIATGSVDQKVRVFAT
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for nuclear migration during vegetative growth as well as development.  Required for retrograde early endosome (EE) transport from the hyphal tip.  Required for localization of dynein to the mitotic spindle poles.  Recruits additional proteins to the dynein complex at SPBs.
What are the official names of this protein?
Nuclear distribution protein nudF 1, Lissencephaly-1 homolog 1, LIS-1 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.
Protein: KPB2_MOUSE
Sequence: MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHDQKDAWVRDNIYSILAVWGLGMAYRKNADRDEDKAKAYELEQNVVKLMRGLLQCMMRQVDKVEKFKHTQSTKDSLHAKYNTATCSTVVGDDQWGHLQVDATSLFLLFLAQMTASGLRIIFTLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQGIPELNASSVGVAKAALEAIDELDLFGAHGGRKSVIHVLPDEVEHCQSILFSMLPRASTSKEIDAGLLSIISFPAFAVEDVNLVNVTKNEIISKLQGRYGCCRFLRDGYKTPREDPHRLHYDPAELKLFENIECEWPVFWTYLIIDGIFNGDAVQVQEYREALEGILIRGKDGIHLVPELYAIPPDKVDEEYKNPHTVDRVPLGKLPHLWGQSLYILSSLLAEGFLATGEIDPLNRRFSTSVKPDVVVQVAVLAENSHIKGLLKEHGMTVQSIADVHPIRVQPGRILSHIYAKLGRNKNMKLSGRPYRHIGVLGTSKLYVIRNHIFTFTPQFTDQHHFYLALDNEMIVEMLRIELAYLCTCWRMTGRPTLTFPVTHTMLTNDGSDIHPAVLSTIRKLEDGYFGGARVKLGNLAEFLTTSFYTHLTFLDPDCDEKLFGDITDRSFSPDSEPDLGGYLEDSSPQESQDELDQYISHLLQSTSLKCYLPPLCKKSEDSHFFSAIHSTRDILSVMAKAKGLETTFFPMILPTKVLSGHRKSLNLVDSPQPLLKTTPEYDYQWPRDDHDEVDCEKLVGQLKDCSNLQDQADILYILYVMKGPRWDTNLFGQHGVTVHSLLSELYGKAGLNQEWSLIRYISGLLRKKVEVLAEACADLLSHQKQLTVGLPPEPREKTISTPLPPEELTELIYEASGQDISIAVLTQEIVVYLAMYVRAQPSLFAEMLRLRIGLIIQVMATELARSLNCSGKEASESLMNLSPFDMKSLLHHILSGKEFGVERSVRPIHSSMSSPAISIHEVGHTGATKTERSGITRLRSEMKQMNRRASADEQFFPLGQTMSNSLHSIKSVRSSTPSSPTGTSSTDSGGQHLGWGEQQGQWLRRRRLDGAINRVPVGFYQKVWKILQKCHGLSIDGYVLPSSTTQEMTPCEIKFAVHVESVLNRVSQPEYRQLLVEAIMVLTLLSDTEMDSIGGIIHVDQIVQLANQLFLQDQVSFGTTDILEKDQATGICHLFYDSAPSGAYGTMTYLTKAVASHLQELLPSSGCQMQ
What is the function of this protein?
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.  The alpha chain may bind calmodulin.
What are the official names of this protein?
Phosphorylase b kinase regulatory subunit alpha, liver isoform, Phosphorylase kinase alpha L subunit.
What is the protein family that this protein belongs to?
Belongs to the phosphorylase b kinase regulatory chain family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ACE2_PONAB
Sequence: MSGSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPNNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDSYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLINAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQRFWENSMLTDPGNVQKVVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLLNMLRLGKSEPWTLALENVVGAKNMNVRPLLDYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGNKAYEWNDNEIYLFRSSVAYAMRKYFLEVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVVLIFTGIRDRKKKNKARNEENPYASIDISKGENNPGFQNTDDVQTSF
What is the function of this protein?
Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis.  Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II.  Also removes the C-terminal residue from three other vasoactive peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin.  Also cleaves other biological peptides, such as apelins, casomorphins and dynorphin A.  Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity.
What are the official names of this protein?
Angiotensin-converting enzyme 2, ACE-related carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M2 family.
What are the subcellular locations of this protein?
[Processed angiotensin-converting enzyme 2]: Secreted. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cell projection, cilium. Apical cell membrane. Note=Detected in both cell membrane and cytoplasm in neurons.
Protein: DEF68_ARATH
Sequence: MGSSKLLVALTLVVMITISYDLFSEIGISAATLVIPTCFENCNATFQDPECNKWCALLAYKDGSCLYPPSEVDDLPPIKRPYIPRCCCNPITLSPPSP
What are the official names of this protein?
Defensin-like protein 68.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: ADRB3_RAT
Sequence: MAPWPHKNGSLAFWSDAPTLDPSAANTSGLPGVPWAAALAGALLALATVGGNLLVITAIARTPRLQTITNVFVTSLATADLVVGLLVMPPGATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSATVSFAPIMSQWWRVGADAEAQECHSNPRCCSFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVAKRQRRLLRRELGRFPPEESPRSPSRSPSPATVGTPTASDGVPSCGRRPARLLPLGEHRALRTLGLIMGIFSLCWLPFFLANVLRALVGPSLVPSGVFIALNWLGYANSAFNPLIYCRSPDFRDAFRRLLCSYGGRGPEEPRVVTFPASPVASRQNSPLNRFDGYEGERPFPT
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  Beta-3 is involved in the regulation of lipolysis and thermogenesis.
What are the official names of this protein?
Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS11_CHLPB
Sequence: MATTSRKKKKVKVTPEGTVHIKASFNNVLVTITDMQGNTVSWSSAGKNGFKGSKKNTPYASQITSESAAKEAYDLGMRYVHVFIKGPGSGRDAAIRALQGAGLEVRSIKDITPLPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RBL_SOLGR
Sequence: SVGFKAGVKEYKLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYRIERVVGEKDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFVEQDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAQEGNEIIREACKWSPELAAACEVWKEIVFNFAAVDVLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UBIG_RHIL3
Sequence: MTEGAKSTIDQGEVDRFSAMAAEWWSPTGKFKPLHKFNPVRLAYIRDKACENFSRDPKSARPLEGLRVLDIGCGGGLLSEPVARMGASVVGADPSEKNIGIASTHAKASGVSVDYRAVTAEGLAEAGETFDIVLNMEVVEHVADVEFFMTTCAKMVRPGGLIFVATINRTMKAAALAIFAAENILRWLPRGTHQYEKLVRPEELEEPLVASGLEITDRTGVSFNPLSNQWNLSKDMDVNYMLLAKRPT
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: Y855_MYCLE
Sequence: MRRSKQGAEGKAEKKAARSAGVCRTTLPGGLRVVTEHLPAVRSASVGVWVGVGSRDEGATVAGAAHFLEHLLFKSTSTRTAMDIAQAIDAVGGELNAFTAKEHTCYYAHVLDSDLELAVDLVADVVLNGRCAVDDVELERDVVLEEIAMRDDDPEDALGDMFLAALFGDHPVGRPVIGTMESVSAMTRTQLHSFHVRRYTPERMVVAVAGNVDHDEMVALVREHFGSRLIRGRQSAPPRKSTGRINGGPALTLGKRDAEQTHVLLGVRTPGRSWEHRWALSVLHTALGGGLSSRLFQEIRETRGLAYSVYSALDIFADSGALSVYAACLPGRFADVMQVISEVLASVAGDGITEAECRIAKGSLRGGIILGLEDSNSWMSRLGRSELNYGKYRGIEHTLQQIDEVTVEQVNALAHQLLNKRYGAAVLGPYASKKTLPRQLRIMVN
What are the official names of this protein?
Uncharacterized zinc protease ML0855.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
Protein: YHAM_SHIF8
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTHQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITAIMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.