PharMolix/UniProtQA huggingface dataset:
Protein: GET3_PENRW
Sequence: MSSAVVHGDDLDMEPTLQSVLNQNTLRWIFVGGKGGVGKTTTSCSLAIQLAKVRKSVLLISTDPAHNLSDAFGQKFGKEARLIDGYSNLSAMEIDPNGSIQDLLATGDGQGEDPMAGLGMGNMMQDLAFSIPGVDEAMSFAEVLKQVKSLSYEVIVFDTAPTGHTLRFLQFPTVLEKALAKLSQLSTQFGPMLNSILGARGGLPGGQNMDELLQKMESLRETISEVNTQFKNPDMTTFVCVCIAEFLSLYETERMIQELTSYNIDTHSIVVNQLLFPKEGSDCEQCTARRKMQKKYLDQIEELYEDFNVVRMPMLVEEVRGKEKLEKFSEMLVTPYVPPQ
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase get3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: PMT6_CANAL
Sequence: MATGYSTGVSPFDLDENNHNDSIHHRHQNHHSQSHDSSGERDDTEIEDIIQKTSKLNINTSTSTKIKNFFFQSSNRHDSSNSPPLREVFIKTINPLILTAISSFVRLYRIDVANSVVWDEAHFGKFGSQYLKRQFYFDVHPPLGKLLIGLSGYLADYDGNFDFESSNVYPDNVNYVFMRIFNCFFGILVTPLAYKTAVILGYNQFTCWLIAFMVIFEQLSLTLSKFILLDSMLLFFTVLTMYCLVKVHTLAIARVGSNSKTPLTKLEIKWYILTGISIGCVCSVKWVGLFVTALVGFYTIVDLWIKFYQTFAIDKKSPKKMSVVNYLIHWVVRIFTLIIIPMTIYVATFKVHFMVLNHTGPDDGTLSTLLQGSLIGNDLQSGPRSVAFGSLVTIRSQGLSPNLIHSHPHNYPQGSQEQQVTTYGFKDDNNEFLFEFGVDAGLRNQHATLENENSTRNGGNDDDYYHVIIHDGDTVRINHKNTGSYLRANAVGAPITSSSYEVSCFGDVESNDWADEWVIEIQSQDQSPDPMFQDEDPSEIHSVSTSFRLKHKQLGCYLATTGKSYPAWGYQQGEVVCKYSVFSRDKNTWWNIEKHVNNKLPLPATEYVPPKPKFWKEFILLNYAMMASNNALIPDPDRFDKLSSEWWEWPILNTGLRMNSWGDADIKYFLLGNPLITWISTIALIVCPLYLLVVGIKYQRQWILLSATDTSNANPANSQSLSLLAARALLPLAGWVLHYVPFILMGRVKYLHHYVPALYFAIFVAGFIVDAILNLDFSYHNNKFQYIFKVVIYSTLYLVICISFWYFKDLSFGMEGSSVDYRHLRLLGSWMI
What is the function of this protein?
Protein mannosyltransferase (PMT) involved in hyphal morphogenesis and drug sensitivity.  Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.  PMT1, PMT2 and PMT4 account for most of the protein-O-glycosylation activity, while PMT5 and PMT6 may specifically modulate a much narrower spectrum of target proteins.  Required for biofilm formation and virulence.
What are the official names of this protein?
Dolichyl-phosphate-mannose--protein mannosyltransferase 6, Protein mannosyltransferase 6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RBSA_BACCR
Sequence: MGMHIEMKNISKAFNGNPVLKNAQFMIETGEVHALMGENGAGKSTLMKILTGVYKKDGGTIKIDGQERTFKNAKEAEEYGIAFIHQELNILPNLTVAENMFLGKELMYGKTGILRTRQMNAIAQQQLAELGLHVRGAMLAEELSVGQQQIIEIAKALMTNASVIIMDEPTAALTDREIETLFTVINKLRKEGVSFVYISHRMEEIFSICDAITILRDGEYVGKRLIPETSFDEVVSMMVGRSIGERYPERNSQIGDVIFEMRNGTKKGKFENVSFQVRKGEILGVAGLMGAGRTDIMKAIFGYEPLDSGQIFINGQEVKIDSPIDAIRQRIAFITEDRKSEGLVLDFSIRENLALPNLENLSKGSVLSNELEQQFTEDMMKLLNVKASSGEQAVKSLSGGNQQKIVIAKWLGIHPQLLILDEPTRGVDVGAKKEIYSIMNKLTEQGDAVIMVSSELPEVLGMSDRVLVIHEGKVGGILGKDEASQESIMALATGGE
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RPO10_METMJ
Sequence: MIPVRCFTCGKVVSTAWKEFKERRDAGEDPKRILDDLGLERYCCRRMLLTHKETVEDLNPYQ
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTD_VIBVY
Sequence: MQHFSRTFLAASIATALFAPYAQAEAILNNSVQEMPTTDQCLVDAEKNDANAEIVIQADNLQAINGDKAIYSGDVEVTQGNKKITAESVTLHQQENIVVAEGNVTFNDGEVKASSSKVTNNMTSETFSLENTEYQFLCQQGRGQAAYIAKTGQAVYELEDGSITSCPADDNAWRLVASSIEVDQDEETATFYHPRFEVLDVPVFYAPYLTLPIGNTRKTGFLFPSVNYGSSDGLEIEVPFYWNIAPNYDLTLTTLYMQQRGVKQDADFRYLSDGWGSGELKGEYLPGDEKYNDEDRWGYQYKHDGIINKQWLVSLDYSQVSDIDYFRDLSSDLGNREDGQLMQQGKVAYRSDFWDMSLQVRDFQILLQDNNQPYRLLPQVKFNFYTPLLGNYLNFDVKSELTQFDIQDASKPNALRAHVEPGLTIPLSTSWATWTTEARLLATYYQQDLDRLTDPTLKSQLDETVARVIPEYRSHARIYLEREAKLFEGYTQSLEPQIQYLYVPEEEQGNIYNYDTTLLQTDYYGLFRSRKYSSIDKIAAANQLSYGASTRFFDDEYKERLNISFGQIYYIDKKTKLTGNQEETSNYSSWAVETDFNYEDFLFYHGGIQYDIDLNAMQLANSTLEYQFTDGFIQGNYRYVTKDYIEDTISFDELDKITRKGISQAGIVGAYNINRHWSASGQYYYDLTEEIDLEWMASLRYQSDCWYIGFTYTNQLVKWRNDVVGGDSNNPVYDTNISVNFGIQGFATKNKAETAAKELDSTDNAITYGRPFYLNN
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RAN_DICDI
Sequence: MAEKEQIKLVLVGDGGVGKTTFVQRHLTGEFEPRYIPTLGVSVHPLIFYTNFGKIHFNVWDTAGQEKFGGLRDGYYIQGNCAIIMFDVTSRISYKNVPNWHSDLTRVCENIPIVLCGNKVDVKDRKVKPSQIVFHRRYNLSYYDVSAKSNYNFEKPFVWLTSKLLGNKAVTLVQQPTLKLPETVLDSNLMSLYEKEVADAAALPLPEDNDDL
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein Ran, GTPase Ran, Ras-like protein TC4, Ras-related nuclear protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1251_HAEIN
Sequence: MMTRKPTSVGEILQEEFLEPLSLKISDLAQILDVHRNTASNIVNNSSRITLEMAVKLAKVFDTTPEFWLNLQTRIDLWDLEHNKRFQQSLANVKPALHRHDTSTFAM
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator HI_1251.
What is the protein family that this protein belongs to?
Belongs to the VapA/VapI family.
Protein: SYP_SULAC
Sequence: MKLTREKWENNFSEWFDWVIREAEIYDYGRYPVKGMGVWLPYGFKIRQAAVDLIRKLLDAKGHEEVLFPLLVPEDLLRREGEHIKGFESEVFWVTKGGEENLDIRLALRPTSETAITYMETYWVQSYKQLPKKYYQIVSVFRYETKATRPMIRLREVSTFKEAHTLHETYEDAERQVKEAIEIYKNFFEELGIPYIMSQRPEWDKFAGAIYTIAFDTIMPDSRVLQIGTVHHLGQHFTKAFDLKVQRKDGTLDYPHQTSYGISDRVIAVAVSINGDDHGTILSPVLAPIKAVIIPIPAKDEKETEKIIEYSEDVAKILVSNGINTVIDKDTEKTPGEKYYIWEIKGVPLRIEIGPRELSSNSVFIKRRDTLQGISVKKENLVSEVVKLLETLRKDLKERAWNFLRSKIRYTDNLEEAKKMLDSKAGIVEVPWCESNECGLKIEETTGARVLGKPYDSPRDVSKSTCVVCKKPAKTTLRLAKTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAK5_MOUSE
Sequence: MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCITPIQLAPMKTIVRGNKSCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGAASRIQGHSEENGFITFSQYSSESDTTADYTTEKYRDRSLYGDDLDLYYKSSHAAKQNGHAMKMKHGDAYYPEMKSLKTDLAGFPVDYHTHLDSLRKSSEYGDLRWDYQRASSSSPLDYSFQLTPSRTAGTSRCSKESLAYSESDWGPSLDDYDRRPKSSYLHQTSPQPAMRQRSKSGSGLQEPMMPFGASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVFSPPLSGSDTYPRGPTKLPQSQSKAGYSSGSHQYPSGYHKASLYHHPSLQTSSQYISTASYLSSLSISSSTYPPPSWGSSSDQQPSRVSHEQFRAALQLVVSPGDPREYLDNFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH
What is the function of this protein?
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival.  Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues.  Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity.  Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD.  Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology.  Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PAK 5, p21-activated kinase 5, PAK-5, p21-activated kinase 7, PAK-7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the mitochondria, and mitochondrial localization is essential for the role in cell survival.
Protein: COBD_CLOAB
Sequence: MLDIIIAVIIDWIIGDPYWFPHPVIYIGKLIKMLEKLGRRFFKQDKWLLVFGGFIVIIVSSISFLIPFIILQGVKKFQVIYHVINIFFLWTVLAAKSLHKEGKKVYTALEKKDIEDARLKLSYIVGRQTEGLSKKEIIRADVETIAENSSDGIIAPLLFAMLGGAPLAMMYKGINTMDSMLGYMNFKYRYIGFFPAKIDDLFNFIPARVTGIIMCLVSPIIGGNIFYSIKIMLRDRKNHKSPNCAYPEAAAAAASGIMLGGTNIYFGEVVEKPTIGEEKNELSDFHITKTIILMYSSEILFIIIYVIIICFLGKH
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNME_BORBU
Sequence: MSKFFERDDDIVALATPFLSSALCVIRSSGASSISKFSKIFSNHSALNSASGNTIHYGYILDSENGCKVDEVVVCLYRAPKSFTGQDAIEVMAHGSVIGIKKIIDLFLKSGFRMAEPGEFTLRAFLAKKIDLTKAEAIHEIIFAKTNKTYSLAVNKLSGALFVKIDAIKKSILNFLSAVSVYLDYEVDDHEISIPFDLILSSKAELKKLINSYKVYEKIDNGVALVLAGSVNAGKSSLFNLFLKKDRSIVSSYPGTTRDYIEASFELDGILFNLFDTAGLRDADNFVERLGIEKSNSLIKEASLVIYVIDVSSNLTKDDFLFIDSNKSNSKILFVLNKIDLKINKSTEEFVRSKVLNSSNLIMISTKNLEGIDILYDKIRALISYERVEIGLDDIIISSNRQMQLLEKAYALILDLLSKIDRQVSYDMLAFDAYEIINCLGEITGEVSSEDVLDNMFKNFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_ACIBC
Sequence: MQLSDFSFELPDELIARYPLETRSASRLLHLDAKGQYHDHMFTDIIDLFEEGDLLVLNDTKVMKARLKGKRATGGAIEILVERMLNHTTAYCHIKASNSPKAGAELFVGEDNIPVIVRGRHENLFVVEFSQPILPVLEQYGQLPIPPYFNREAEEIDTERYQTVFHNPEKIASVAAPTASLHFDEELLAKLDQKGVKKTFVTLHVGAGTFMPVRTDDITNHVMHSEWCDVPQETIDLILATKARGNKVIAVGTTATRALESAAQAHGGKIAAWTGDTQIFIYPGYEFCIVDRLITNFHLPESTLLMLVSALSNRENILAAYEHAVKDRYRFFSYGDAMLIDKLEV
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_LACDB
Sequence: MEFKHTSVLLHETIDNLAPQSGGTYVDATFGGGGHARYLLRKLDKGNLIGFDQDQYAIDTAQSNFAAFLKEDSQPRLQLVHNNFSHLKEELAKLGISGIDGIYYDLGVSSPQLDQAERGFSYRFDARLDMRMDQSQDFDAYQLVNQYDQKQLADVLYRYGDEKFSRQIARKIVERRRGKPIETTFELVEIIKEAIPAAARRRGGHPAKKSFQAIRVEVNHELDVLRASLEEAISLLNPGGRISVITFQSLEDKIVKQTFKKYSEVEIPRGMPVVPEGIKPTLRLVNRKSITASEEELAENNRSHSAKLRVAEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTC1_MYCTO
Sequence: MLARAGEVGRAGPAIRWLGGIGAVIPLLALVLVLVVLVIEAMGAIRLNGLHFFTATEWNPGNTYGETVVTDGVAHPVGAYYGALPLIVGTLATSAIALIIAVPVSVGAALVIVERLPKRLAEAVGIVLELLAGIPSVVVGLWGAMTFGPFIAHHIAPVIAHNAPDVPVLNYLRGDPGNGEGMLVSGLVLAVMVVPIIATTTHDLFRQVPVLPREGAIALGMSNWECVRRVTLPWVSSGIVGAVVLGLGRALGETMAVAMVSGAVLGAMPANIYATMTTIAATIVSQLDSAMTDSTNFAVKTLAEVGLVLMVITLLTNVAARGMVRRVSRTALPVGRGI
What is the function of this protein?
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Phosphate transport system permease protein PstC 1.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARNF_KLEP7
Sequence: MGFFWALLSVGLVSAAQLLLRSAMVALPPLTDIVAFLQHLLHFQPGTFGLFFGLLGYLLSMVCWYFALHRLPLSKAYALLSLSYILVWAAAIWLPGWHEPFYWQSLLGVAIIVAGVLTIFWPVKRR
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NAR1_PHANO
Sequence: MSAILSADDLNDFISPGVACIKPIETLPAKPEDSSNPYEVTTEDKAAASQPPPPASISLTDCLACSGCVTSAEAVLVSLQSHSEVLTTLDTYRSLRAPWQTQNGTNGTNGTNGTTNGHSTNGTTTNGINGHSHEGKLFVASVSPQSRASIAAVFNVSEAEAGNMIAQLLSGPSGLKTGGHQGSDFTWVLDTNVVREACLVAAADEVANALSPETSNPSTKPGSEGAIDTTPKQPILTSACPGWICYAEKTHPYILPHLSRLKSPQALTGTLIKSVLSQQYNIPPSQIWHVAIMPCFDKKLEASRSELTSSAWLPNHDATQDPVRDVDCVITARELLHLASARGINFASLPRTPLSASERTPFPDPKLDAFLFPHTRRKNQDVVAGSSGGYLYHILQTYQAQNPGSSISVSRGRNADVVEYSLVRGSETIIRAARFYGFRNIQNLVRRLKPAKASRLPGGKTGVSRKPGAAAGGDVKDYAYVEVMACPGGCTNGGGQVKITEVEEVRAYEGVESTNGDTLAPKPGPKEQKEWLAKVDEAYFSGSDSEEEKVDQDGDQNMQDATTNGHTSEPDIVNGISRRKINDVVAHWSHLTGVDTQKLLYTSYRKVESDVGKKQSDMERVAGLAVTVGGGW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: ASP2_BLAGE
Sequence: MIGLKLVTVLFAVATITHAAELQRVPLYKLVHVFINTQYAGITKIGNQNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEKLKPKYISDGNVQVKFFDTGSAVGRGIEDSLTISNLTTSQQDIVLADELSQEVCILSADVVVGIAAPGCPNALKGKTVLENFVEENLIAPVFSIHHARFQDGEHFGEIIFGGSDWKYVDGEFTYVPLVGDDSWKFRLDGVKIGDTTVAPAGTQAIIDTSKAIIVGPKAYVNPINEAIGCVVEKTTTRRICKLDCSKIPSLPDVTFVINGRNFNISSQYYIQQNGNLCYSGFQPCGHSDHFFIGDFFVDHYYSEFNWENKTMGFGRSVESV
What is the function of this protein?
Functions as a digestive enzyme in the cockroach.
What are the official names of this protein?
Aspartic protease Bla g 2, Allergen Bla g II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: ZAPA_BACCN
Sequence: MSQQKGKKSRINVEIYGQQYSVVGDESTSHIRMVAAIVDDKMRELNAKNPSLDTSRLAVLTAVNVIHDYIKLKEEHEKLKESMRQKGME
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell. In sporulating cells, localizes near the cell poles.
Protein: OXA1_YEAST
Sequence: MFKLTSRLVTSRFAASSRLATARTIVLPRPHPSWISFQAKRFNSTGPNANDVSEIQTQLPSIDELTSSAPSLSASTSDLIANTTQTVGELSSHIGYLNSIGLAQTWYWPSDIIQHVLEAVHVYSGLPWWGTIAATTILIRCLMFPLYVKSSDTVARNSHIKPELDALNNKLMSTTDLQQGQLVAMQRKKLLSSHGIKNRWLAAPMLQIPIALGFFNALRHMANYPVDGFANQGVAWFTDLTQADPYLGLQVITAAVFISFTRLGGETGAQQFSSPMKRLFTILPIISIPATMNLSSAVVLYFAFNGAFSVLQTMILRNKWVRSKLKITEVAKPRTPIAGASPTENMGIFQSLKHNIQKARDQAERRQLMQDNEKKLQESFKEKRQNSKIKIVHKSNFINNKK
What is the function of this protein?
Mitochondrial inner membrane insertase that mediates the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the inner membrane.  Links mitoribosomes with the inner membrane (PubMed:22904327).  Forms pores capable of accommodating translocating protein segments (PubMed:22829595).  Essential for the activity and assembly of cytochrome c oxidase (PubMed:22904327).  Plays a central role in the translocation and export of the N-terminal part of the COX2 protein into the mitochondrial intermembrane space.
What are the official names of this protein?
Mitochondrial inner membrane protein OXA1, Cytochrome oxidase biogenesis protein OXA1, Oxidase assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family.
Protein: MTR1B_HUMAN
Sequence: MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
What is the function of this protein?
High affinity receptor for melatonin.  Likely to mediate the reproductive and circadian actions of melatonin.  The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
What are the official names of this protein?
Melatonin receptor type 1B, Mel-1B-R, Mel1b receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OP10_MAIZE
Sequence: MSLHAARGGPHEDLSWSAIGRRAPRDVVTFGDREGGGGMRSAQQGPGAVRVDEASSASTFRELDEAFLQTQTKIWLGEVLHLRFGEDALVADLLADGELLFQVSKVLWKMLLKNNREQLKQSKVYIYERLSFGRSSGKYMPYSKVDSFLKICQILGLAGIDLFTPSDVVEKRNVRKVCICIRSVSKKSLILHLNVPDFDVVTYTISMPNYVVGGIRRNLEQTQYSSSSSSGYSPCARSKVLQQQIIFGGQNDQHEDTHYDSDEAESKLSLLEPEDSVNEDNFAAVLSQFNDAHNKGSEGYGESGCGKHGEKSLAESVGSLNIGIIDFEFMDSTPLIHDKESCSLLEPEDSVNEDNFAAVLSKFNDAPNKESKGYGESGRGKHGEKSLAESVGSLNIGIVDSEFMDSSPLIHDKESCSPLEPEGSVNEDNFTAVLSQFNDAPNKESEGYGESGCGKHGEKSLVESVGSLNIGIVDSEFMDSSPLIHDKESCSPLEPEDSVNEDNFAAVLSQFNDAPNKESEGYGESGRGKHGEKSLAESVGSLNIGIIDSEFMDSSPLIHDKESCFPLEPEGSVNEDNFTAVLSQFNDAPNKESEGYGESGCGKHGEKSLVESVGSLNIGIVDSEFMDSSPLIHDKESCSPLEPEDSVNEDNFTAVLSQFNDAPNKESEAYGESGCGKHGENSLDESVGSLNIGVIDSEFMDSSPLIHDKESCSPLEPEDSVNEDNFAAVLSQYSDGPNEGNEGYGESGHYKHEEKSLDESVGSLTIGIIDSEFMDSSRPIHDKESCSTGSAADQCSRTIPAKYELSSEESDSTGSHLVFDSGKNYLELNNHSVTDLERIYNGHATSVDQYVRGNGETLADHPKKEEAGLQKDTGTIAQHRDTLACDGESVCSSCEEPRRGLNGEPSDFSSESHSRLTPTHNTGGKLSMVSEHPVHNMESDMTGMASDSTNPELNPEASTRNEMDGSRSTDNPVEPENVAQDSATRGRPEGDAPRSGKGVLRSVAGGITLVGAVFFMFHLSAALLQKKQGGKLCDGHTISFGKICSEQRKGQEHGQRKRP
What is the function of this protein?
Cereal endosperm protein required for the ring-shaped distribution of 22 kDa alpha- and 16 kDa gamma-zeins in protein bodies.
What are the official names of this protein?
Protein OPAQUE10.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=In endosperm, predominantly deposited into protein bodies, at the interface between the alpha-zein-rich region and the gamma-zein-rich region.
Protein: HXD8_MOUSE
Sequence: MSSYFVNPLYSKYKAAAAAAAAAAAAAAGEAINPTYYDCHFAPEVSGRHAAALQLYGNSAAGFPHAHPHPHPHPSPPPGCGGGGGPGPGQDYFHAGAGSPTAAYQAAPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHTLALTERQVKIWFQNRRMKWKKENNKDKFPASRPEAKDGDPKKEVSGLEEDGAEGCPTN
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D8, Homeobox protein Hox-4.3, Homeobox protein Hox-5.4.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURQ2_VIBCH
Sequence: MTNDALIAALSHLVSEGRNPDTMDIDLLSSQEIVERLNQQDKQVPLAVEAVLPQIAQAVDKITAAFKQGGRLIYLGAGTSGRLGVLDASECPPTFGVSDQMVIGLIAGGKEAMFTAQEGAEDNATLGAHDLQQIDFSSKDVLVGIAASGRTPYVIGALEYANDLGATTIALSCNPDSPIAEIAQIAISPVVGPEALTGSTRLKSGTAQKLVLNMLTTASMIRLGKSYQNLMVDVRATNRKLIARAVRIVMQATDCQREEAEALLKESHNNAKLAILMHLTGMNYEQATAKLSQSDGFLRRAMEEHEE
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase 2, MurNAc-6-P etherase 2, N-acetylmuramic acid 6-phosphate hydrolase 2, N-acetylmuramic acid 6-phosphate lyase 2.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: GLL1_CHICK
Sequence: MRIVYLLLPFILLLAQGAAGSSQALGRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIWG
What is the function of this protein?
Has bactericidal activity.  Potent activity against E. coli ML-35, L. monocytogenes EGD and C. albicans.
What are the official names of this protein?
Gallinacin-1, Gal-1, Beta-defensin 1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule.