PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_THEMA
Sequence: MKKEKKDYYEILGVPRDATQEEIKRAYKRLVKEWHPDRHPENRKEAEQRFKEIQEAYEVLSDPQKRAMYDRFGYVGEQPTYQETESGGFFDDIFRDFENIFNRDIFDVFFGERPHQEERREYARRGEDIRYEIEVTLSDLINGAEIPVEYERYETCPRCGGTGVEPNAGYMDCPSCGGTGRIREERRSFFGYFVSERTCERCGGTGKIPREYCHECGGSGRVLRKVRRTVKIPPNVEDGTHLRITGGGNAGYYGGPYGDLIIIVRVKPDPRFKKSGSDLVYDVTIDYLQAILGTTVEVPLPEGGTTMLKIPPGTQPETVFRLKGKGLPNRYGRRGDLIVNVHVEIPKSLSREERKVLEELAKKRGVTIG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWI5_SALSA
Sequence: MDTERSSEICGNVPDVTLSTPKGKVFSTPKGAHKRTPYSGHTKVNSSFKSPVQTSSTSPAKPEEEIEELKKRRAKLDSEIALLEKDGIRVDELEQHIDLLHEYNDIKDIGQSLVGRIAALRGVTTRDLYGQFGLELDD
What is the function of this protein?
Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.
What are the official names of this protein?
DNA repair protein SWI5 homolog, Protein SAE3 homolog.
What is the protein family that this protein belongs to?
Belongs to the SWI5/SAE3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1586_METKA
Sequence: MSEARQQSSSEGGGDLSDYEEKFEQCCTLLEQRIIQDDQIPRNVRRAAKQAIEALKEEGQSPGVRASTAISTLEEVVNDQNTPEYARTVLLQVIATLEQVKDEV
What are the official names of this protein?
UPF0147 protein MK1586.
What is the protein family that this protein belongs to?
Belongs to the UPF0147 family.
Protein: CCD42_ORYSJ
Sequence: MAPSSSSCHDAAASMLLCAEDNSSILWLEDEEGEVGERRSGGCRSMVGDLAAGGGGGSGGGGVEEEEDMFPRQSEECVASLVEREQAHMPRADYGERLRGGGGDVDLRVRSEAIGWIWEVYTYYNFSSVTAYLAVNYLDRFLSQYELPEGRDWMTQLLSVACLSIAAKMEETVVPQCLDLQIGEPRFLFEVETIHRMELLVLTNLNWRMQAVTPFSYIDYFLRKLNSGNAAPRSWLLRSSELILRIAAGTGFLEFRPSEIAAAVAATVAGEATGVVEEDIAEAFTHVDKGRVLQCQEAIQDHHYSMATINTVQPKPASTRRGSASASSSSVPESPVAVLDAGCLSYKSDDTDAATIASHGGGRRKSCFDSSPVTSKKRRKLSR
What are the official names of this protein?
Cyclin-D4-2, G1/S-specific cyclin-D4-2, CycD4;2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
Protein: IHFB_BURCJ
Sequence: MTKSELVAQLASRFPQLVLKDADFAVKTMLDAMSDALAKGHRIEIRGFGSFGLNRRPARVGRNPKSGEKVQVPEKFVPHFKPGKELRERVDGRAGEPLKADDPDDER
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RR14_STAPU
Sequence: MAKKSMIERDKKRKFLSAKYSIQRQQLKEQINQSLSLDEKAHLYRKLQSLPRNSAPTRITRRCFVTGRPKAVYRDFGLSRHVLREMAHACLLPGVIKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: XTH16_ARATH
Sequence: MGRILNRTVLMTLLVVTMAGTAFSGSFNEEFDLTWGEHRGKIFSGGKMLSLSLDRVSGSGFKSKKEYLFGRIDMQLKLVAGNSAGTVTAYYLSSEGPTHDEIDFEFLGNETGKPYVLHTNVFAQGKGNREQQFYLWFDPTKNFHTYSLVWRPQHIIFMVDNVPIRVFNNAEQLGVPFPKNQPMKIYSSLWNADDWATRGGLVKTDWSKAPFTAYYRGFNAAACTVSSGSSFCDPKFKSSFTNGESQVANELNAYGRRRLRWVQKYFMIYDYCSDLKRFPQGFPPECRKSRV
What is the function of this protein?
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).
What are the official names of this protein?
Probable xyloglucan endotransglucosylase/hydrolase protein 16, At-XTH16, XTH-16.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 2 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: BIOD_MYCUA
Sequence: MTVLCVTGTCTGVGKTVVTAALASQANQAGIDVVVCKPVQTGTGNGDDDLAEIGRLSGVTELVGLARYPLPMAPVAAAEQAGQPLPSRDQLVQHIRGLDRPGRLTLVEGAGGLLVELADSGGTLRDLAVDLGAAMLVVVAAGLGTLNHTALTLEALAAQKVSCAGLVLGSWPAHPGLVESSNRDALARLAPMRAVLSAGAAQLSVADFAVMSAGAFDREWVATLVG
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHE4_SACSH
Sequence: LDTLEALSQPERVIQVKIQIRGSDGKLKTFMGWRSQHNSALGPYKGGVRYSPNVTQDEVIALSMIMTWKNSLLLLPYGGGKGGIRVDPKKLTLKELEDLSRKYVQLIHNYLGSDVDIPAPDINTNPQTMAWFLDEYIKITGEVDFAVFTGKPSELGGIGVRLYSTGLGVATIAREAANKFIGGIEGSRVIIQGFGNVGSFTAKFLNEMGAKIIGVSDIGGGVISDDGIDVNKALEVVQSTGSVVNYPEGKKVTNEELLTSDCDILIPAAVENVINKFNAPKVKAKLIVEGANGPLAADADEIIKQRGIVVIPDILANAGGVVGSYVEWANNKSGGIISDEEAKKLIIDRMTNAFNALYEFHKRKFADQDLRTVAMALRVDRVVGMKARAI
What are the official names of this protein?
NADP-specific glutamate dehydrogenase, NADP-GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: MRAZ_SALEP
Sequence: MFRGATLVNLDSKGRLTVPTRYREQLIESATGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWYQQVKEDIDAEQSATETLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL16_HELMI
Sequence: MLLPKRVKWRRVQRGRLKGKSKGGNSVAFGEYGLQALEAAWITSRQIEAARIAMTRYIKRGGKVWIKIFPDKPITAKPAETRMGSGKGSPEYWVAVVKPGRIMFELAGVPEDTAKEAMRLAMHKLPIKCKFVKREEVGGEANES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SYE_AGRFC
Sequence: MTTSGVRVRIAPSPTGEPHVGTAYIALFNYLFAKKHGGEFILRIEDTDATRSTLEYEQKVLEALRWTGLTWSEGPDVGGPYGPYRQSERKPMYWPYAEELLEKGHAFRCFCTPERLEQMREAQRAAGKPPKYDGLCLHLKAEEVTTRVAAGEANVVRMKIPTEGSCDFHDGVYGDVSIPWDSVDMQVLIKADGMPTYHMANVIDDHLMKITHVARGEEWLASVPKHILLYRYFGWDQPTFMHLSLMRNADKSKLSKRKNPTSISYYSALGYLPEALMNFLGLFFIQIAEGEELLTMEELAAKFDPEALSKAGAIFDIQKLDWLNGRWLREKLTPEDFIARTLEWAMENSRLTEGLKLAQSRISKLGELPNLAGFLVSSDVGLTPASFAGLKSKPEEIHEILTTVAADLEKMPDWNVEAIEAELRDIAERTGKKLRVVTPPLFVAVSGSSRSLPLFDSMALLGRSVVRQRLKVAIAVVATMVGSGS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_BURM7
Sequence: MESLRIYNTLARDKQDFVPRQPGEVRMYVCGITVYDYCHIGHARMVVVFDIVQRWLRARGYRVTYVRNITDIDDKIIRRAVENGETIQSLTRRFTDAMNADFDALGVERPDLEPRATEFIPQMLGMIEKLEANGYAYQAKDGDVNYSVRKFANYGRLSGKSLEDLRAGERVAANDAKEDPLDFVLWKRAKPQEPAGASWESKYGAGRPGWHIECSAMGCTLLGAHFDIHGGGQDLQFPHHENEIAQSEGATGQTFVNYWMHNGFVQVDSEKMSKSLGNFFTIREVLEKFDAEVVRFFIVRTHYRSPLNYSDVHLDDARASLTRLYTALKDATPDAQPLDWSEAHAQRFAAAMNDDFNTAVAVAVLFELATEVNRTREPALARQLRLLAGLLGLLGREPREFLQHAAGAARTGALEPHEIEARIAARVAAKQAKNYAEADRIRAELLEAGIALEDKPGGSTEWRRV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_ACIAD
Sequence: MPQVKLKEGEPVDVAIRRFKRSCEKAGVLADVRKREFYEKPTQERKRKKAAAVKRYQKKLARESVRTTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: AMPC_LYSLA
Sequence: MKRLLAFCLLFFAALGQAKVPPPARSAADAEIQRAVAAFMQQYQVPGVAVGITVDGAERYYNYGVSSRKTQAKVGANTLFEVGSVSKTFTATLASYAQVNQQLSLADHPGKYLPEMKGHDFDKVTLLNLGTHTAGGFPMQVPTQVKTDQQLTAYFQSWHPQYPAGTKRTYANPGIGMLGVIAAKSMRMPFQKAMTGVLLPKLGLTNTYLTVPPAKMAFYAQGYDDKGQPVRMSPGALWEPTYGIKTTARDLLRFVEINLDQVKVEPKLKRAIDGTHVGYYRLGEMTQGLVWEQLPYPASETSLQANSSQKVIFESNAVAALTPPRPPQANVLINKTGSTRGFGAYVAFNPARKIGIVLLMNRSVPMDGRIKLAHTILDTAGGMAK
What is the function of this protein?
This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
What are the official names of this protein?
Beta-lactamase, Cephalosporinase.
What is the protein family that this protein belongs to?
Belongs to the class-C beta-lactamase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MPCP3_ARATH
Sequence: MESPKNSLIPSFLYSSSSSPRSFLLDQVLNSNSNAAFEKSPSPAPRSSPTSMISRKNFLIASPTEPGKGIEMYSPAFYAACTFGGILSCGLTHMTVTPLDLVKCNMQIDPAKYKSISSGFGILLKEQGVKGFFRGWVPTLLGYSAQGACKFGFYEYFKKTYSDLAGPEYTAKYKTLIYLAGSASAEIIADIALCPFEAVKVRVQTQPGFARGMSDGFPKFIKSEGYGGLYKGLAPLWGRQIPYTMMKFASFETIVEMIYKYAIPNPKSECSKGLQLGVSFAGGYVAGVFCAIVSHPADNLVSFLNNAKGATVGDAVKKIGMVGLFTRGLPLRIVMIGTLTGAQWGLYDAFKVFVGLPTTGGVAPAPAIAATEAKA
What is the function of this protein?
Transport of phosphate groups from the cytosol to the mitochondrial matrix.  Mediates salt stress tolerance through an ATP-dependent pathway and via modulation of the gibberellin metabolism.
What are the official names of this protein?
Mitochondrial phosphate carrier protein 3, mitochondrial, Mitochondrial phosphate transporter 3, MPT3, Phosphate transporter 3;1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ACT18_DICDI
Sequence: MEREEVQAIVIDNGSDMCKAGFAGDDAPRAVFQSIVGRPRYTGVMDVMGQKDSYIGDEAHSRKGFLTLKYPIERGIVTNWDDMEEIWHHTFYNELGVAPEEHPVLLTEQPLNPKKNREKMTQIMFETFNTPAMYVAIQAVLSLYSSGRTTGIVMDSGDGVSHAVSIYEGHALPHAILRLDLAGRDLSDYMMKILTKRGYSFTTTAEKEIIKDIKEKLSYVALDFDAEMLTAASSTTLEKSYELPDGKVITIGNERFRCPEALFQPSLLAMESAGIHETIYNSIMKCDVDIRRYLFGNVILSGGSTMFPGIADRMNKELTALAPSTMKIKIIAPPERKYSVWVGGSILASLSSFQEMWISKEEYNESGPSIVHRKCSNYLK
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity).
What are the official names of this protein?
Actin-18, Actin-3-sub 2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GPR52_MOUSE
Sequence: MNESRWTEWRILNMSSSIVNVSEHHSCPLGFGHYSVEDVCIFETVVIVLLTFLIISGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLLVGVTCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIIMIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTCFIVCLLYAPAALVVCFTYFHIFKICRQHTKEINDRRARFPSHEVEASREAGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCVCAKDQEAQDPKPRRRANSCSI
What is the function of this protein?
G- protein coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (By similarity).  May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity.  These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241, PubMed:28583861).  Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).
What are the official names of this protein?
G-protein coupled receptor 52.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPX_ACIET
Sequence: MAEKKGSSSEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPTGDAGREGRGDLPTPAEIKTNLDHYVIGQEKAKRTLAVAVYNHYKRLRHKDKAGKDEVELSKSNILLIGPTGSGKTLLAQTLARQLDVPFVMADATTLTEAGYVGEDVENIVQKLLQSCNYDVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQIDTTNILFICGGAFAGLEKVIENRTEASGIGFGAAVRSKKQRSLTEVFQDIEPEDLIKFGLIPELVGRMPVVTALAELSEDALVQILTEPKNALVKQYSKLLAMEGVELEIRPAALKSIARKAIARKTGARGLRSILEQALIGTMFDLPNVSNVEKVVVDEATIEENKAPLLVYREAAKTA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CML8_ORYSJ
Sequence: MASKYRGYYHDEASSAAGGGGGGGGGDGYRREKQVRKKRLTAQKRKEIKEAFDLFDTDGSGTIDPKELNVAMRALGFEMTPEQIHQMIAEVDKDGSGTIDFDEFVHMMTDKMGERDAREELNKAFKIIDKDNNGKISDVDIQRLAIETGEPFTLDEVREMIEAADENGDGEVDHEEFLKMMKRIGFGAGFF
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML8, Calmodulin-like protein 8.
Protein: GTS1_YEAST
Sequence: MRFRSSSHSLKHVDRELKELINSSENANKCGECGNFYPTWCSVNLGVFLCGRCASVHRKVFGSRDDDAFSNVKSLSMDRWTREDIDELVSLGGNKGNARFWNPKNVPFPFDGDDDKAIVEHYIRDKYILGKFRYDEIKPEDFGSRMDDFDGESDRFDERNRSRSRSRSHSFYKGGHNRSDYGGSRDSFQSSGSRYSRQLAELKDMGFGDTNKNLDALSSAHGNINRAIDYLEKSSSSRNSVSAAATTSTPPLPRRRATTSGPQPAIFDGTNVITPDFTSNSASFVQAKPAVFDGTLQQYYDPATGMIYVDQQQYAMAMQQQQQQQQQLAVAQAQAQAQAQAQAQVQAQAQAQAQAQAQAQQIQMQQLQMQQQQQAPLSFQQMSQGGNLPQGYFYTQ
What is the function of this protein?
Appears to modulate the timing of budding to obtain an appropriate cell size independent of the DNA replication cycle.  Transcription factor involved in both heat resistance and flocculation.
What are the official names of this protein?
Protein GTS1, Protein LSR1.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRDR_NITEU
Sequence: MRCPFCGAEDTSVVDSRISEEGARIRRRRRCVECEKRFTTYETVELRFPQVIKQDGNRVEFNREKLYTSFARALHKRPVPTGQVDAAIERILQKLLGSGVQEISSRTIGEWVMQELYSLDKVAYIRFASVYRSFEDVGDFQEVIREVQSSPQNGDGPSS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PPAL_MACFA
Sequence: MAGKRSGWSRAALLQLLLGANLMVMPPTQARSLRFVTLLYRHGDRSPVKTYPKDPYQEEEWPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRKTPEYQNESSRNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLHLPPWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRRNLTLMATTSQLPKLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQEDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFLHLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPGYRHVADGEDHA
What are the official names of this protein?
Lysosomal acid phosphatase, LAP.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass membrane protein; Lumenal side. Lysosome lumen. Note=The soluble form arises by proteolytic processing of the membrane-bound form.
Protein: RFRNP_IGNH4
Sequence: MIKFVIDTSAVTDPRLRQLFGVNELWEVVEKYLELMALAKLKLGFSFYTTPSVMKEIKGFLERSMCPSEIISKLGVWILVKDVSQTEAKIPARVFLEYVAEVKRRLDKGLRVAEESTRRAMEGGEIGEHIRNLREKYREATRKGLLDSVADLEAAILALELGAVLVTNDEGLCKLASKLGVSCIDPLTFVKTIEEYLNLIKRHG
What is the function of this protein?
RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.
What are the official names of this protein?
RNA-free ribonuclease P, RNA-free RNase P, Protein-only RNase P.
What is the protein family that this protein belongs to?
Belongs to the HARP family.
Protein: RS17_THEM4
Sequence: MPKKRLIGEVLSDKMDKTVVVAVSTLVKHPRVGKYIKRTKKYYAHDENNECRVGDIVEIVESRPLSKLKRWKVERIVERSVFAEKAPEEDLEGGSNNDN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DTD_PSYCK
Sequence: MRSLIQRVKYASVSVDGQEVGAIEQGVLAYIGLGHDDNLQSAQRMIDKILTYRIFDNDDDPAKYGKVDKNVQQVGGGLLLVSQFTLMAKTDKGRRPEFGSAMAPDMAQALFAQLVDYAKTQYLTVATGQFGADMQVLSVNDGPLNFLLEVH
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_CLOBL
Sequence: MIQQQTRLKVADNSGAKEIMCIRVLGGSHRKWGNIGDVIVASVKSATPGGVVKKGEVVKAVIVRSVKGLRRADGSYIKFDENAAVIIKDDKNPKGTRIFGPVARELRDKEFNKILSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: OXR1_MAGO7
Sequence: MTIKFASLILAGLGLGSGALGSVTFRREESSWTNDSLTSVFAQQAKGLFLPRTVISFQGQEWFENVTERWDIYAPPTFKVSVSPSTEKDVESAVKLAAKFKIPFLATGGRHGYGTTLGKLKNGLSIDLSLLNQFSIDSKAATITVGPGVRFRDIFTPLYEAGFQVPTGTCSCVGMIGATLGGGIGRLNGLDGLMIDALESARVVTADGRTLTVSEKENKDLFWGMRGAGQNFGVVVSATYKLKPLYAAGVWTNVDLIFSPDKNATYFDVVTSMEVPPQLTIASVVTYNATLDEPQLIATLTWTGPRDEALAAMKPILDVGPRHSEVTEATYATLPRVATFGTTDAVCAPGQIYDIYGVGLRRLDSAAWRSTFSKMARFYAAEPAGRASSILYETWPVQATVAVPDDATAYPWRDASTYVLIQMRWDRPGSPLERAADRLGAELRSDLSATGGYQGAGPAVYVNYAHGDERLEDIYGARKLPRLAKLKKQYDPGNVFRFHHALPTKYP
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of pyriculol and pyriculariol, two heptaketides that induce lesion formation upon application on rice leaves but are dispensable for pathogenicity (PubMed:27902426).  The highly reducing polyketide synthase synthesizes the heptaketide backbone of pyriculol and pyriculariol (PubMed:27902426).  Pyriculol and pyriculariol contain several hydroxyl moieties and double bonds, so it can be assumed that several reduction steps occur during biosynthesis.  These reactions could be executed by PKS19 itself or partly by the tailoring enzymes OXR1, OXR2, RED1, RED2 or RED3, identified within the cluster (Probable).  The FAD-linked oxidoreductase OXR1 is the only tailoring enzyme for which the function has been determined yet, and is involved in the oxidation of dihydropyriculol and dihydropyriculariol into pyriculol and pyriculariol, respectively (PubMed:27902426).
What are the official names of this protein?
FAD-linked oxidoreductase OXR1, Pyriculol/pyriculariol biosynthesis cluster protein OXR1.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: COTJB_BACSU
Sequence: MAKKVDAEYYRQLEQIQAADFVLVELSLYLNTHPHDEDALKQFNQYSGYSRHLKRQFESSYGPLLQFGNSPAGKDWDWGKGPWPWQV
What is the function of this protein?
The cotJ operon proteins affect spore coat composition.  They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat.
What are the official names of this protein?
Protein CotJB.
Protein: RL27_PSYWF
Sequence: MAHKKAAGSTRNGRDSNPKMLGVKVFGGQDVVAGNIIVRQRGTEFHAGAGVGMGRDHTLFALTDGVVKFDTKGKFNRRYVSVQEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: MNMC_SHEAM
Sequence: MSDSVTSCLLLPILETMPMPVITTLFMFYYPFRTGSTNFSAPIVSPLALLSGQLSIKGGKIMPISRHRVNFFNPMPEFFAIDMAMPLSLPLPEGPCVVLFEALPEPPLWQWLLAAAQVNSAYPETNAAYASNASITSIQHTSKKPLQIIMLLKDEAELNALAMDASHPLSPFAMAASHIKGGQRFHLDDNCWLDFYLCEPNKAATLATFDKASIDVLICPKGEFEQAALELAHQGSILIGDTKPDMPAALPIKPPFKPRDISIVGAGVAGASLALSLLRRGHKVTLYCADAAPGIGASGNRQGAIYPLLTPEDDHLTRLFVPAFLYAKRFVESLAHHPLPFDFCGVLQTGHDERATERIEKLLSKTWPKQVAVRVDADEANHIAGVAIDKGGIYYPQGGWVSPAKLCEAAIEEAKTMGLECHFDVNITSITRADEGWRLNTQTGEIDAHELVLATGHRITELAQTKSLQLAPFRGQVSHVPTRGKLEQLKTVLCAHGYFTPRDASSGSHCMGASYVRGDTSVEYREQEQQENLHKMQESYPGKDWVEYLDISEGSARAGIRMVSRDHLPMAGAAPDVAAIQTQYQAIGHGPKGAQYWQTHAAPVHPGLYIFSGLGSRGLSSGPLIAECLADSLSGTLPVLDGDVMEALNPNRMWLRKLKKGKALD
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAP8A_STAAU
Sequence: MESTLELTKIKEVLQKNLKILIILPLLFLIISAIVTFFVLSPKYQANTQILVNQTKGDNPQFMAQEVQSNIQLVNTYKEIVKSPRILDEVSKDLNNKYSPSKLSSMLTITNQENTQLINIQVKSGHKQDSEKIANSFAKVTSKQIPKIMSLDNVSILSKADGTAVKVAPKTVVNLIGAFFLGLVVALIYIFFKVIFDKRIKDEEDVEKELGLPVLGSIQKFN
What is the function of this protein?
Required for the biosynthesis of type 8 capsular polysaccharide (Cap8/CP8).  Might act as the chain-length regulator.
What are the official names of this protein?
Capsular polysaccharide type 8 biosynthesis protein cap8A.
What is the protein family that this protein belongs to?
Belongs to the CpsC/CapA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.