PharMolix/UniProtQA huggingface dataset:
Protein: SBT24_ARATH
Sequence: METNPRKLRSYSYICLIVCIFVLVVCAILSRAEEKEGKGENDDHIPKIYSILVEGEPLAFRASTNINSKAMALEAKKIEEIHDEILGSTLEKGSYTKLYSFKHVINAIAVRTTASQAKKLGKTKGVKAVEEDKGVKLMTTYTPDFLELPQQVWQKISNEGDRRAGEDIVIGFVDTGINPTHPSFAALDLTNPYSSNLSRLHFSGDCEIGPFFPPGSCNGKIISARFFSAGARASGALNSSLDILSPFDASGHGSHVASIAAGNAGVPVIVDGFFYGRASGMAPRSRIAVYKAIYPSIGTLVDVIAAIDQAIMDGVDVLTLSVGPDEPPVDKPTVLGIFDLAMLLARKAGVFVVQAVGNNGPSPSSVLSYSPWVVGVAAGNTDRSYPAPLILDGGQTVQGVGLSGPTLGAPLVQHRLVLAKDAVRTNGSVLQPLTRDIEECQRPENFDPAAVFGSIVICTFSDGFYNQMSTVLAITQTARTLGFMGFILIANPRFGDYVAEPVIFSAPGILIPTVSAAQIILRYYEEKTFRDTRGVATQFGARARIGEGRNSVFAGKAPVVSRFSSRGPAFIDATRSPLDVLKPDILAPGHQIWGAWSLPSAFDPILTGRSFAILSGTSMATPHIAGIGALIKQLNPSWTPAMIASAISTTANEYDSNGEIISAEYYELSRLFPSNHFDHGAGHVNPARALDPGLVLPAGFEDYISFLCSLPNISPATIRDATGVLCTTTLSHPANLNHPSVTISALKESLVVRRSFQDVSNKTETYLGSVLPPNGTTVRLTPTWFTVPPQKTQDLDIEFNVTQVLNKFTFGEVVLTGSLNHIIRIPLSVKTI
What is the function of this protein?
Serine protease required for epidermal surface formation in embryos and juvenile plants (PubMed:11731449, PubMed:17376810, PubMed:23318634).  Involved in embryonic cuticle formation downstream of BHLH95/ZOU (PubMed:23318634).
What are the official names of this protein?
Subtilisin-like protease SBT2.4, Protein ABNORMAL LEAF SHAPE 1, Subtilase subfamily 2 member 4, AtSBT2.4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTH_CUTAK
Sequence: MSPSWLVIGLGNPGPRYDGTRHNVGADVIAELCRRAGEKLSPARGQRAELVRTRLSSAGLGVPAVDAQTVILMRSRTYMNESGIAVSKVASFAGITPDHLIVVHDEIDLDPGRLRLKKGGGDNGHNGLKSIRAHLRTGDFIRVRLGVGRPPGHQDPADWVLARVPARQRAEMGVQVALAADAVESIIIQGLAAAQNRFNS
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEK10_HUMAN
Sequence: MPDQDKKVKTTEKSTDKQQEITIRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMTKSEPAIRAGGHRARGQWHESTEAVELENFSINYKNERNFSKHPQRKLFQEIFTALVKNRLISREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGIENLAQYMEIVANEYLGYGEEQHTVDKLVNMTYIFQKLAAVKDQREWVTTSGAHKTLVNLLGARDTNVLLGSLLALASLAESQECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCAEPQVKEQVKLYEGIPVLLSLLHSDHLKLLWSIVWILVQVCEDPETSVEIRIWGGIKQLLHILQGDRNFVSDHSSIGSLSSANAAGRIQQLHLSEDLSPREIQENTFSLQAACCAALTELVLNDTNAHQVVQENGVYTIAKLILPNKQKNAAKSNLLQCYAFRALRFLFSMERNRPLFKRLFPTDLFEIFIDIGHYVRDISAYEELVSKLNLLVEDELKQIAENIESINQNKAPLKYIGNYAILDHLGSGAFGCVYKVRKHSGQNLLAMKEVNLHNPAFGKDKKDRDSSVRNIVSELTIIKEQLYHPNIVRYYKTFLENDRLYIVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNIMLGDKDKVTVTDFGLAKQKQENSKLTSVVGTILYSCPEVLKSEPYGEKADVWAVGCILYQMATLSPPFYSTNMLSLATKIVEAVYEPVPEGIYSEKVTDTISRCLTPDAEARPDIVEVSSMISDVMMKYLDNLSTSQLSLEKKLERERRRTQRYFMEANRNTVTCHHELAVLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQASYGKDEDRACDEILSDDNFNLENAEKDTYSEVDDELDISDNSSSSSSSPLKESTFNILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLLLKVPPHMLRAHIKEIEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQASAGIAVSQRKVRQISDPIQQILIQLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKLSQGSPEPIEPNFFTADYHLLHRSSGGNSLSPNDPTGLPTSIELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPTKR
What is the function of this protein?
Plays a role in the cellular response to UV irradiation.  Mediates G2/M cell cycle arrest, MEK autoactivation and ERK1/2-signaling pathway activation in response to UV irradiation.  In ciliated cells of airways, it is involved in the regulation of mucociliary transport (PubMed:31959991).
What are the official names of this protein?
Serine/threonine-protein kinase Nek10, Never in mitosis A-related kinase 10, NimA-related protein kinase 10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Protein: SWC3_ASHGO
Sequence: MARLRSRTATTEKDATESSKVPVPRRRRGQHEDTEEPDTYGLEDDEKSSGRPFRILEKLPCSAEPPRYDVLTHALSVRDSAVLYNSLLASRRTWIKAEMFELYWSKQYMNMKERERMLKEGIDPDDIDQSAAREKMHKLCDGILTGGPHTLPVRLFILKNDEIEQKWQFMQESRKKEKEVRRKREAEEKERRREERKRLQQLKKERKLKEVEHTKKEKIERKRENDTERDQLRKGRKDNKGPSVLSRMGTTIKSKGLTTFSKAQQQEIDNQKMIANLNLLAQRDPALNKLMIAVANGQAPPADVERFKVFIERARNMEPPPNWKPRLSSRPVIKRTEEPTVEQQESASQTPSTPLPRKASPESSQVDNLSSPPHGSDPNSSFTEASMSDSRGELSETKSGGSLVPDSTGSSGQALDKGPTDASGSANDLSRPGATLSSTDGAPPLKQETIPVRDMGDKNADKPLEAHGAISEKGTTITIKAEEGTAPRQKRKYTKRKKEVEDEDKSMQLTTFQQKYLNGADILFEYLENSNMRFLFPKDAILEQLENEESYLMSWIVVHNKKEIEQFKLKVLKGLNKNKPNEEETEVQPCLFNVYEHPNCPEVLYTPMTVTLSNIPKKFTPIILNSVNPAESVRAYMSTILARGRRLNGFNLWYQLDAYDDKDLAESLRCELKEYEQGFKSKRQKKQL
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
SWR1-complex protein 3.
What is the protein family that this protein belongs to?
Belongs to the SWC3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TM218_DANRE
Sequence: MADVVLGVGTGVFIITLIWILTLALTIILSRATGPTKLGIIPVVLLALIITLVLVFFPRAAEVPAPQRAAQIVDMFFIGRYVLLSLVSLVFLAALFMLLPLHFLEPIYAKPLRTH
What is the function of this protein?
May be involved in ciliary biogenesis or function.
What are the official names of this protein?
Transmembrane protein 218.
What is the protein family that this protein belongs to?
Belongs to the TMEM218 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: SECY_MYCCT
Sequence: MVIKKPANKVDKKSTFKSSNKKKNPFKSSFLTKNKDLIYRILFTLLALIIIRLGVYITVPGVTLDKRFATDSSRIQFFQLLSTLGGGSIGRFSILALGVSPYITASIIVQLLSTDVIPVLTRWSKSGERGRKKLDKLTKIIMIPFALMQAEATIFTLSSQGLIIPGWDNTNAIANSAFYYILIPLVMLGGSFFMLWIADQITIKGIGNGISIVIFIGIIISMPSNLKSTFEYWVSNSGEEANIFFSGLLNFMIYISVFLLVILSVVIMNEAERKIPIQQTGSGLTDSSEHTPYLPLKLNNAGVIPVIFASAIISTPITISQIIEAVNPDSGFVIFTRDYLSFNTWWGISIFGILIVLFTFLYSQVQINPEKIAENFQKSGTFIPGIKPGKDTTKYLTGIINRLSVVGSVFLAIIALLPYVISKLTQLPSNLAIGGTGLIICISVAIQTVQQLKGRIIQQNFIEKKKEKFTNNINKNKTSHIW
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABZ_CHLMU
Sequence: MSEKPVLGIQDIQNLLPHRYPFLLVDKILSYDLNTRSIVAQKNVTINEPFFVGHFPEAPIMPGVLILEALAQAAGVLLGIILENDRDKKIALFLGIQKAKFRQPVKPGDVLILKAEFSLISAKGGKAIAQAFVGSQIVAEGELSFVLVKKESI
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5API_HETMG
Sequence: MDYQRLLFLFAVAMVITTTVALPQDTALMDGNGTGQLQKRGTPCKCLGYTGVYWFMITRCPNGHGYNLSCPYFLGVCCVKK
What is the function of this protein?
Toxin that inhibits rat ASIC3 channels (IC(50)=13. 8 uM) (PubMed:36287966).  Also able to bind T.  californica muscle-type nicotinic acetylcholine receptors (nAChR) (PubMed:36287966).
What are the official names of this protein?
Pi-stichotoxin-Hmg5a, Pi-SHTX-Hmg5a, Pi-AnmTX Hmg 1b-5.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
Protein: UFC1_DANRE
Sequence: MADEATRKAVSEIPLLKTNSGPRDKELWVQRLREEYLALIKYVENNKAADNDWFRLESNKEGTRWFGKCWYIHELLKYEFDMEFDIPVTYPATAPEVAIPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLIAKGLIQHKDQNS
What is the function of this protein?
E1-like enzyme which specifically catalyzes the second step in ufmylation.  Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage.  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: RK28_ARATH
Sequence: MTTMATQGAWLRMTSSAKSMTKSTVTSKELGFLTSQLSGLRISYTPSDVINRISLPSFPGIQPIVARRICPFTGKKANRANKVSFSNHKTKKLQFVNLQYKRVWWEAGKRFVKLRLSTKALKTIEKNGLDAVAKKAGIDLRKK
What are the official names of this protein?
50S ribosomal protein L28, chloroplastic, CL28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CHS2_CAEEL
Sequence: MMNTLDHRPLGRMETMEGKPDEDEVPTSSNSDAKGKGYYYSSGTVPTDDSTLEEKCQQKTFDPSCPTPKTPVIVPNREFDPNFSTVTENKGWDIFRLLPPKPDRLGHGFWHDASLQVLKLATFLVLFLLTLGSAVVAKSTFILMTSAIGWGGQTITICNQVISEATQNTVKLKNAHVVKWVWATLLALSAPEALCFVRSMHRTMFRNVKRPTFIQFVFVLIIETFHSIGVGILVFRIFPDLDAVTAAQLTNAMCFVPAILSVISRKPNKSALLLVIIDFAAIAAQSSGFWALPMFLPNLQKHLVAIPVSLTLISLAWWQNFVHRDSVFPPVRTLAKFAQRLSERRSKTYAFVSLWKICIYVVCCFLFISSRMKIEDMLQKDPFGEKLLSVAGHDMNQTQIEKFQLRINQMIEQANREAGFYAAAEKKKQPPKKQPKADEAEQVDAGEYMMKRFKRFIGDAGENEEEEPEEEEFSSYNIYSNYVERNQLTMAYDALWLVIFQFGAVFVCYHSSKFACKVMMQRMGFALPMALSVPVTVLLLSTNCRMRQKDSCYGTNVLTVELFWQCNGASMSLADFILTPQTWIWLCWLASQFWITIHLWNPKHERLAKSEKLFILPYYIGAFVDQSLAFNRRRDDKAKIKAEDLEFDAEDSSLTYETIPGLQNKTPPSVCSASSSKLENGLIRDSASSADAITKIYACATMWHETGVEMTCMLKSLFRMDEDQCARRNAQKYLKVIDPDYYEFEAHIFFDDAYDVNEYGEPEINKFVKQIVNVIDQAASAVHQTQMRLKPPKKAKTPYGGKLTYIMPGKNKLFIHLKDNQKIRHRKRWSQVMYLYYLLGYRLMMKVDDPSRKEIISENTFILTLDGDVDFTPSSVYLLVDLMKKNRRLGAACGRIHPRGDGAMVWYQKFEYAIGHWLQKATEHMIGCVMCSPGCFSLFRAYALMDDNVARRYALKSEEPKHFIQYDQGEDRWLCTLLLQRGYRVEYCAASDAQTFAPEGFNEFFNQRRRWIPSTIFNIMDLLKDYRNVVRVNESISIWYIIYQLVMLISSILGPGTIFVMIIGAISISFSIDTLISLVIVSIPVVVFIVVCLTAKPEHQLICAQTIGAIFAMLMTAVVVGTSLQLQKDGLLSPHSMFTVAVATSFLTAAILHPLEFTCIIPGTIYFLAIPCMYMLLPIYSVCNMHTVSWGTREDPRPTEKNTLAKKTPGNLESGDGAGNSENWCTRFLCCGRGTVHPMTMVINEKLNEVIKKVDRLDRKHHPSLARRASILSSTGGTIQIDKCSEADEDEQAEIEDALEMSNQSHAAKKNQKWKQAQSEAWLADKALKRAEREYLEPEEESFWNDVIERYLSPLIMDGKDMDRLRAGLIAIRNSHTVYFLMINIVFIISVLVLQIHKDCLNIEWPLGPKFNHTVRPCYANHDDNQKEEVWVMTRLQLEPIGLVFLIFFVSILVIQFLAMLCHRFGTLAHIIASTELFCFRKTMDRLSEDELVAQNAVEIARELQAIRGIDENAHNIDNPTEDRGISRRRVVQNLESSRKSMMKRKTETLDAAFKKRFFALSSEQTPDPAGFSARDNSKRLTLRKGTIRALEHRRDSLFGTLDNRKDDEVDATSMRGPAQRRLERLFTAQQDQNSPTSDGNRRKSNSRPWDQPTSSATSSGDVELRRF
What is the function of this protein?
May be involved in chitin synthesis in the pharynx during larval development.
What are the official names of this protein?
Chitin synthase chs-2, Chitin-UDP acetyl-glucosaminyl transferase chs-2.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class IV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPA_SALAR
Sequence: MERYENLFAQLNVRREGAFVPFVTLGDPGIEQSLKIIDTLIDAGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPTQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYAHCEKVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADDDLLRQIASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPVQVSAAVRAGAAGAISGSAIVNIIEKNHNTSPDQMLAELKSFVYAMKAASRV
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RIMP_MYCGI
Sequence: MAERSTDFRPGLPSQRQVVELLDGEFARAGYDIEDVVIDAATRPPRIVVIADGDRGLDLDAVAELSRLASEQLDTLDTPPYVLEVTSPGVDRPLTEEKHYRRAQGRLAEVTLADGSTLTGRIGAVQNATVALVVREARSNLTVRDIALDAVVKAVVQVEFSPPSPRELELAGVSGKET
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y765_HAEIN
Sequence: MKISMIFLPHFLYYTVPTFYLFGLLIMHNAAQHNYVISLTTEQKRRKHITEEFGKQNIPFEFFDAITPDIIEETAKKFNITLDRSPKAKLSDGEIGCALSHIVLWDLALENNLNYINIFEDDIHLGENAKELLEIDYISDDIHVLKLEANGKMFFKQPKSVKCDRNVYPMTVKQSGCAGYTVTAKGAKYLLELVKNKPLDVAVDSLVFEDFLHFKDYKIVQLSPGICVQDFVLHPDNPFESSLQEGRDRVHGNQRKSSILEKIKNEFGRVKIKMFGKQVPFK
What are the official names of this protein?
Putative glycosyltransferase HI_0765.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 25 family.
Protein: KGUA_LATSS
Sequence: MSNRGMLIVLSGPSGVGKGTVRQAMLEDEFRDFHYSVSMTTRKPRPGEQDGVDYYFVSKEEFEQEIANDGMLEYAQYVDNYYGTPMKYVNQTLESGRDVLLEIEVQGAMQVREKCPDGVFIFLTPPDLLELRNRIQKRGTDDQATIDKRMQKAADEIRMMENYDYAVVNDEIPNAVQRIEKIIESEHLRVPRVIDQYKKMIGE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBS_SOLHA
Sequence: MIVGYRSTIITLSHPKLGNGKTISSNAIFQRSCRVRCSHSTPSSMNGFEDARDRIRESFGKVELSPSSYDTAWVAMVPSKHSLNEPCFPQCLDWIIENQREDGSWGLNPSHPLLLKDSLSSTLACLLALTKWRVGDEQIKRGLGFIETQSWAIDNKDQISPLGFEIIFPSMIKSAEKLNLNLAINKRDSTIKRALQNEFTRNIEYMSEGVGELCDWKEIIKLHQRQNGSLFDSPATTAAALIYHQHDKKCYEYLNSILQQHKNWVPTMYPTKIHSLLCLVDTLQNLGVHRHFKSEIKKALDEIYRLWQQKNEQIFSNVTHCAMAFRLLRMSYYDVSSDELAEFVDEEHFFAISGKYTSHVEILELHKASQLAIDHEKDDILDKINNWTRTFMEQKLLNNGFIDRMSKKEVELALRKFYTISDLAENRRCIKSYEENNFKILKAAYRSPNIYNKDLFIFSIRNFELCQAQHQEELQQFKRWFEDYRLDQLGIAERYIHDTYLCAVIVVPEPELSDARLLYAKYVLLLTIVDDQFDSFASTDECLNIIELVERWDDYASVGYKSEKVKVFFSTLYKSIEELVTIAEIKQGRSVKNHLLNLWLELVKLMLMERVEWFSGKTIPSIEEYLYVTSITFGARLIPLTTQYFLGIKISEDILESDEIYGLCNCTGRVLRILNDLQDSKKEQKEDSVTIVTLLMKSMSEEEAIMKIKEILEMNRRELLKMVLVQKKGSQLPQICKDIFWRTSNWADFIYLQTDGYRIAEEMKNHIDEVFYKPLNH
What is the function of this protein?
(2Z,6Z)-farnesyl diphosphate cyclizing enzyme.  Produces (+)-alpha-santalene, (+)-endo-beta-bergamotene, (-)-endo-alpha-bergamotene, and at lower amounts, (-)exo-alpha-bergamotene and (+)-epi-beta-santalene.  Not able to use geranyl diphosphate, E,E-farnesyl diphosphate or E,E,E-geranylgeranyl diphosphate as substrates, but able to use Neryl diphosphate to make the monoterpene terpineol.
What are the official names of this protein?
Santalene and bergamotene synthase, chloroplastic, (+)-alpha-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing), (+)-endo-beta-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing), (-)-endo-alpha-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing).
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpse subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BAK_MOUSE
Sequence: MASGQGPGPPKVGCDESPSPSEQQVAQDTEEVFRSYVFYLHQQEQETQGAAAPANPEMDNLPLEPNSILGQVGRQLALIGDDINRRYDTEFQNLLEQLQPTAGNAYELFTKIASSLFKSGISWGRVVALLGFGYRLALYVYQRGLTGFLGQVTCFLADIILHHYIARWIAQRGGWVAALNFRRDPILTVMVIFGVVLLGQFVVHRFFRS
What is the function of this protein?
In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2.
What are the official names of this protein?
Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: TEX52_HUMAN
Sequence: MASNRQRSLRGPSHPSHMEEPFLQMVQASESLPPSQTWAQREFFLPSESWEFPGFTRQAYHQLALKLPPCTDMKSKVRQRLIHPWKGGAQHTWGFHTWLDVCRLPATFPTQPDRPYDSNVWRWLTDSNAHRCPPTEHPIPPPSWMGQNSFLTFIHCYPTFVDMKRKKQVIFRTVKELKEVEKLKLRSEARAPPLDAQGNIQPPASFKKYRHISAGGRFEPQGLQLMPNPFPNNFARSWPCPNPLPHYQEKVLKLALLPSAPLSQDLIRDFQTLIKDRTALPLHHLSKAQASKSPARKRKRRPGHF
What are the official names of this protein?
Testis-expressed protein 52.
Protein: CWP19_SOLLC
Sequence: STRTPEFLGLDNQCGVWA
What are the official names of this protein?
76 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: MAN1_HUMAN
Sequence: MAAAAASAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRGNKTRNSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGEERDPETEEPLWASRTVNGSRLVPYSCRENYSDSEEEDDDDVASSRQVLKDDSLSRHRPRRTHSKPLPPLTAKSAGGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAAEQGGGCDQVDSSPVPRYRVNAKKLTPLLPPPLTDMDSTLDSSTGSLLKTNNHIGGGAFSVDSPRIYSNSLPPSAAVAASSSLRINHANHTGSNHTYLKNTYNKPKLSEPEEELLQQFKREEVSPTGSFSAHYLSMFLLTAACLFFLILGLTYLGMRGTGVSEDGELSIENPFGETFGKIQESEKTLMMNTLYKLHDRLAQLAGDHECGSSSQRTLSVQEAAAYLKDLGPEYEGIFNTSLQWILENGKDVGIRCVGFGPEEELTNITDVQFLQSTRPLMSFWCRFRRAFVTVTHRLLLLCLGVVMVCVVLRYMKYRWTKEEEETRQMYDMVVKIIDVLRSHNEACQENKDLQPYMPIPHVRDSLIQPHDRKKMKKVWDRAVDFLAANESRVRTETRRIGGADFLVWRWIQPSASCDKILVIPSKVWQGQAFHLDRRNSPPNSLTPCLKIRNMFDPVMEIGDQWHLAIQEAILEKCSDNDGIVHIAVDKNSREGCVYVKCLSPEYAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTSNTPLKPSNKHMNSMSHLRLRTGLTNSQGSS
What is the function of this protein?
Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins.  Antagonizes TGF-beta-induced cell proliferation arrest.
What are the official names of this protein?
Inner nuclear membrane protein Man1, LEM domain-containing protein 3.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: RIN4_ARATH
Sequence: MARSNVPKFGNWEAEENVPYTAYFDKARKTRAPGSKIMNPNDPEYNSDSQSQAPPHPPSSRTKPEQVDTVRRSREHMRSREESELKQFGDAGGSSNEAANKRQGRASQNNSYDNKSPLHKNSYDGTGKSRPKPTNLRADESPEKVTVVPKFGDWDENNPSSADGYTHIFNKVREERSSGANVSGSSRTPTHQSSRNPNNTSSCCCFGFGGK
What is the function of this protein?
Essential regulator of plant defense, which plays a central role in resistance in case of infection by a pathogen.  It is a common target for both type III avirulence proteins from P. syringae (AvrB, AvrRpm1 and AvrRpt2) and for the plant Resistance (R) proteins RPM1 and RPS2.  In strains carrying the appropriate R gene for avirulence proteins of the pathogen, its association with avirulence proteins triggers a defense system including the hypersensitive response, which limits the spread of disease.  In contrast, in plants lacking appropriate R genes, its association with avirulence proteins of the pathogen impairs the defense system and leads to the pathogen multiplication.
What are the official names of this protein?
RPM1-interacting protein 4.
What is the protein family that this protein belongs to?
Belongs to the RIN4 family.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein.
Protein: YSAB_SALTI
Sequence: MIMKYFCTVMIAIALVGCTATPPPTQKAQQSKVSPTRTLDMEALCKAQAAQRYNTGAQKIAVTGFEQFQGSYEMRGNTFRKESFVCSFDADGQFLHLSMR
What are the official names of this protein?
Uncharacterized lipoprotein YsaB.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ADDB_STRPM
Sequence: MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKEREVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDLPSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQQDYNQDSPLQSFARAIKLGLLNNQLSKTVIVIDGFSRFSAEEDYLLSLLNNNCQEVIIGSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFEATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGDMDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKSGLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQELFKSQKQLGASLVDKLILFFKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFHHIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLTQSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELVLSVPTVINETFDDLSPYLKELISFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINRQDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIPLKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEPFDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQEKNFHLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLAALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKEHLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQLKAITRFEADLDMAQARRLVTLPAKEKKECFLTLMRKESHL
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: RL27_ECO57
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RS5_ARCFU
Sequence: MTEDWVPKTKLGRLVADGKIKTMDEALASNLPLKEPEIVDILLPDLEDDVLEISMVQRMTDSGRRTKFRVTAVVGNRNGYVGIGTGKASQVAPAIQKAINNAKLNIFKVQRGCGSWECGCGGDHSLPFKVTGTSGSVRVTLIPGPKGLGIVAGDVAKRVIELAGVKDVWSFTKGQTKTTVNFAKATYEALKKTMYVKR
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: FBX9_BOVIN
Sequence: MAEAEEDCHSEAVREGDDDDENESPAETDLQAQLQRFRAQWMFELAPGGGSGNLESRPCRAARGSLLRAADTRGKQELAKEEKARELFLKAVEEEQNGALYEAIKFYRRAMQLVPDIEFKITYTRSPDGDGVGNSYIEDTDDDSKMADLLSYFQQQLTFQESVLKLCQPELESSQTHISALPMEVLMYVFRWVVSSDLDLRSLEQLSQVCRGFYICARDPEIWRLACLKVWGRSCIKLVPYTSWREMFLERPRVRFDGVYISKTTYIRQGEQSLDGFYRAWHQVEYYRYVRFFPDGHVMMLTTPEEPQSIVPRLRTRNTRTDAILLGHYRLSQDTDNQTKVFAVITKKKEEKALDHKYRYFRRAPVQEADQNFHVGLQLCSSGHQSFNKLIWIHHSCHITYKSTGETAVTAFEIDKMYTPLLFARVRSYTAFSERPL
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability.  Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation.  In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex.  As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1.  Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway (By similarity).  Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation (By similarity).
What are the official names of this protein?
F-box only protein 9.
What are the subcellular locations of this protein?
Cytoplasm.