PharMolix/UniProtQA huggingface dataset:
Protein: NU6M_BOSMU
Sequence: MMLYIVFILSVIFVIGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPEIWLLNKAVLGAFITALLMEFFMVYYVLKDKEVEIVFEFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSLFIGVVVIMEITRGN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RBS_PROMP
Sequence: MPFQSSVGDYQTVATLETFGFLPPMTQEEIYDQIAYIIAQGWSPVIEHVHPSGSMQTYWSYWKLPFFGEKDLNLVVSELEACHRAYPDHHVRIIGYDAYTQSQGTAFAVFQGR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity (PubMed:22155772).  There are estimated to be 152 RuBisCO holoenzymes per carboxysome (PubMed:22155772).
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.
Protein: PAFA_MYCPA
Sequence: MQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDNLVQLVTHDRAGEWVLEDLLVDAEQRLADEGIGGDIYLFKNNTDSAGNSYGCHENYLIVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATFCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMCETTTMLKVGTAALVLEMIEAGVPFRDFSLDNPIRAIREVSHDITGRRPVRLAGGRQASALDIQREYYSRAVEHLQTREPNAQIEQIVDLWGRQLDAVESQDFAKVDTEIDWVIKRKLFQRYQDRYNMELSDPKIAQLDLAYHDIKRGRGVFDLLQRKGLAARVTTDEDIAEAVDTPPQTTRARLRGEFISAAQAAGRDFTVDWVHLKLNDQAQRTVLCKDPFRAVDERVKRLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: NPRT2_ARATH
Sequence: MEPKENGSELGQKIIDGPTNPMVTPLLNDLYQFTMAYAYWKAGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQECLPGSEEAFCDYLRGLDCSDVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGKSKSLLEFGARRAQGPDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFMSTDEIVDKVLRSADGKTTCEDFVSHVQTWLKKIQYSPSLSGIFSETNQSELAAFTSYALAFPKTFLALVDTYDVMKSGIPNFCAVALALNDFGYKALGIRLDSGDLAYLSREARNFFCTVERELKVPGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLVEINNQPRIKLSEDVTKVSIPCKKRSYRLYGKEGYPLVDIMTGENEPPPKVGERLLCRHPFNESKRAYVVPQRVEELLKCYWRGSADEAREVLPPLKEIRDRCIKQLENMRPDHMRRLNPTPYKVSVSAKLYDFIHFLWLNEAPVGELQ
What is the function of this protein?
Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.  Helps prevent cellular oxidative stress via its role in NAD biosynthesis.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: CCNA_DROME
Sequence: MASFQIHQDMSNKENPGIKIPAGVKNTKQPLAVIGGKAEKNALAPRANFAVLNGNNNVPRPAGKVQVFRDVRNLNVDENVEYGAKKSNVVPVVEQFKTFSVYEDNNDTQVAPSGKSLASLVDKENHDVKFGAGQKELVDYDLDSTPMSVTDVQSPMSVDRSILGVIQSSDISVGTETGVSPTGRVKELPPRNDRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISELSLMEGETYLQYLPSLMSSASVALARHILGMEMWTPRLEEITTYKLEDLKTVVLHLCHTHKTAKELNTQAMREKYNRDTYKKVAMMESVEMSKDDFDQLCEAYNCKQKEDEHQQPDINTKSNVNLFYKF
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.  Interacts with the Cdk1 and Cdk2 protein kinases to form MPF.  G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
What are the official names of this protein?
G2/mitotic-specific cyclin-A.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: PACC_ASPGI
Sequence: MSEHQDNNNNNTAATAASPSSTVAPVPTPVPQEQLSSQLPAPAAPAPVSAATPVPSVTATAAAATAAVASPPMNGSPRPSEELSCLWQGCSEKCSSAEALYEHICERHVGRKSTNNLNLTCQWGSCRTTTVKRDHITSHIRVHVPLKPHKCEFCGKAFKRPQDLKKHVKTHADDSVLVRSPEPGSRNPDMMFPGGGKGYAAAAHYFEPSLNPVPSQAYGHGAPQYYQAHPPPQPANPSYGNVYYALNHGHDGHASYESKKRGYDALNEFFGDLKRRQFDLHSYAAVGQRLLGLQNLSLPILAGGPLPEYQPMPAPVAVGGGYSPGGHGPPVYHLPPMSNVRTKNDLLNIDQFLQQMQETIYENDDHVAAAGVAQPGAHYVHGGMSYRTTHSPPSQLPPSHATATTSAATMMSHPATHSPSTGTPALTPPSSAQSYTSGRSPISMSSAHRVSPPHHDGGSGMYPRLPSATMADSMTAGYPTTSSAAPPSTLGGIFDDDRRRYTGGTLQRARPEERRLSVDMDIRQDGKEVGDRTPTGKEAGSQSASPVRISANLIDPALHSNSSSDAESALRTAQAATEVAERTDSQWVEKVRLLEYLRNYIASRLDRGEYDADARRALARHSPEMRHDGHMEGVETSHTLTKPEEPAASPAIRSLSDDSVMYPTLRGLGGDEDTKMHS
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity).
What are the official names of this protein?
pH-response transcription factor pacC/RIM101.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RNFB_STUS1
Sequence: MSAVLIAVLALLALCLLGGAILGFAAVRFRVEGDPIAEQINALLPQTQCGQCGYPGCKPYAEAIAGGDKINKCPPGGEATIQALADLLDVEPEPLDAEGGEKPQMVAYIREAECIGCTKCIQACPVDAIVGAARQMHTVIISECTGCDLCVEPCPVDCIDMIEVGSNLQSWKWNRPLAPGQLIATDREQAA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
Protein: MURE_STAHJ
Sequence: MNANELFEKIRVKQVIGTLDINVTDITTDSRTASEGSIFVASKGYTVDSHKFCQNVVDQGAKVIVVNHQQDINGDVTQVIVPDTLRVASLLAHTLYDFPSHQLTTIGVTGTNGKTSIATMIHLIYRGLGKGSAYLGTNGFQINEHKTRGANTTPETVSLTKKIKQAVDENAEAMTMEVSSHGLSLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYAVLNNDDDFSKYLASVTPYEIFTYGIDHDAQFMAKNIQESLQGVHFDFDTPIGTYSVKTPYVGKFNISNIMAAMIAVWSKGTSMEDIVRVVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNKLIDAVKPFVKQKLIFLIGMAGERDLTKTPEMGAVACRADYVIFTPDNPANDDPKMLTAELAKGATHNHYVEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRDDLIGLEAAYKKFGGGPSEH
What is the function of this protein?
Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_TRIEI
Sequence: MSRRRVIQRRPIPPDPKYNSRLVTMIVRRIMRHGKKSVAYNIVYDAFKAIEERTDSDPLELFEKAVRNLTPLVEVKARRVGGATYQVPMEVRSDRGTTLALRWLVQYSRSRGGKTMAMKLANELMDAANETGSAIRKREETHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ASNA_LIMRD
Sequence: MDLTIPKDYDPRLSIRETEAAIRYIRETFQDEFGKELNLQRMSAPMFVEKSTGLNDNLNGVEQPVSFEMKDMPNETVEIVHSLAKWKRLALKRYGFGMHEGLYTNMNAIRKEEDLDNFHSIYVDQWDWEKIISKDERTEETLKDTVRDIFKVIKHMEHEVWYKFPQAVYHLPDEIHFVTTQELEDRWPDLTPLEREDKIAKELGAVFVMKIGDKLQRSGKPHDGRAPDYDDWSLNGDIIFWYEPLQRRIEVSSMGIRVSPESMKYQLEQADATDREKLPFHKMLLNGELPYTIGGGIGQSRLCMLLLGKAHIGEVQASIWPEDMIKKCEENHIQIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2193_COXBN
Sequence: MVKTNILSNHFLVAMPQLNDFTFTKAVIYVSQHDAKGALGIIINRPLALTLGKVLEHLNIEIAQPQIANHPVLMGGPIGQEHGFIVYEQESPQGAEILLSASKDMLDDIAKNKGPDDFLITLGYAGWEAGQLENEIARNDWLVVPFNRKILFETPLKSRWQKAAALIGVDINQLSGQIGHA
What are the official names of this protein?
UPF0301 protein CBUD_2193.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: HYPA_CHLL3
Sequence: MHEMSIAMSIVDAVDAKARAEGAVRISLIELKIGKLAGILPEALRFCFSAAATGSLAGQAQLVIDEPDGRGRCSDCGHEFSVDFYYARCPECGSLRIVIVSGEEFLIQSIIIDEEGE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: PSAI_MESVI
Sequence: MIASYLPSILVPLVGLVFPAIAMASLFLYIEQEEIS
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL6_LISMH
Sequence: MSRIGKKTIVIPAGVTVTLNGSTATVKGPKGELVKEFNPEITIKIEGNEINVSRPTDNKNHRALHGTTRAILNNMVVGVSEGYEKKLELIGVGYRAQKQGDKLVLNVGYSHPVEFVAPKGVDIEVPANTQVIVKGYNKEHVGELAANIRAVRPPEPYKGKGIRYEGEHVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: Y1853_ARATH
Sequence: MANAKETTFYITISVVAFVIGKIVIALLFYKRWKRKHTIHENGFPVKGGGKMVMFRSQLLNSVSSDMFMKKTHKLSNKDILGSGGFGTVYRLVIDDSTTFAVKRLNRGTSERDRGFHRELEAMADIKHRNIVTLHGYFTSPHYNLLIYELMPNGSLDSFLHGRKALDWASRYRIAVGAARGISYLHHDCIPHIIHRDIKSSNILLDHNMEARVSDFGLATLMEPDKTHVSTFVAGTFGYLAPEYFDTGKATMKGDVYSFGVVLLELLTGRKPTDDEFFEEGTKLVTWVKGVVRDQREEVVIDNRLRGSSVQENEEMNDVFGIAMMCLEPEPAIRPAMTEVVKLLEYIKLSTRSSF
What are the official names of this protein?
Receptor-like serine/threonine-protein kinase At1g78530.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SEC59_YEAST
Sequence: MVAIIPHASFTTIKLTQKTEGSQMPTEEICKINMRTRKFDVGGNSRDFECFYSNFVQTVILLGTFFYCVERLQPWSIVTADISYKQIFVNVFVVCLIMVGLIFTKYWQHGYKSLPKFDTIYSLYLPFMVSLLFDTSSTVINTILILSVLNSYRWRTQLVVIILQLCLIFFNFEAGDRLKNIISIVINSLLSLILKYIGQLKSLDNIDSNLFSILLTNILYVSEAGTVHFRILKGIILALTTIISINYVLKKVMHFKPFMLSISFAIGLPLFANTFIHLEDGENPLLWLVKYILESTIRQKILFAWSSILILSIPSILIEKDSLSLNTSRKLWHFIIFLLIIPSFQMDSNFVKIALSGTIPVFLSIEYIRFQNLPPLGSAIELQLRRFADDRDHSGPLIISYLYLLFGISTPLLMNNSPMGLIGLGIGDSLASIIGKRYGRIRWKGTQKTLEGTLAFIVTSFIVCLVLLRFDKAAIFNHLTTLQLLTLCTLSGVLEGNSVLNDNILIPAFMMICEKLITL
What is the function of this protein?
Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors.  It is required for spore germination.  Has an essential role in cellular metabolism.
What are the official names of this protein?
Dolichol kinase.
What is the protein family that this protein belongs to?
Belongs to the polyprenol kinase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane.
Protein: GLO22_HAEIN
Sequence: MNIEIIPVTAFQQNCSLIWDDEKNAAIIDPGGEAERLIQRIEELDLNLKVLLLTHGHLDHVGAAMQLKQHFGVEIWGSNEKDKFLFESLPEQAQRFGLPNIDAFLPDRWFNQEGEILKLDGFNFEILHLPGHTPGHIGFIEHEKKVAFTGDVLFQGGIGRTDFPRGDYETLISSIRTKLLPLNDDIIIIAGHGSYTTIGQEKRSNPFLNSKS
What is the function of this protein?
Type II glyoxalase, isozyme of GloB, that hydrolyzes (R)-S-lactoylglutathione to (R)-lactate and glutathione.  Plays a role in methylglyoxal (MG) detoxification.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase GloC, Accessory type II glyoxalase, Glyoxalase II 2, GlxII-2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: CTTB2_ECHTE
Sequence: MATDGASCEPDFARAPEDAAGAPAEAARKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGDKEKKPVCTNPLSILEAVMAHCRKMQERMSTQLAAAESRQKKLEMEKLQLQTLEQEHKTLAARLEEERVKNKHVVLMLVKECKQLSGKVIEEAQKVEEALAQLEEEKKRASGLEEELSGEKRRSAEMEAQMEKQLSEFDTEREQLRAKLSREEAHTTDLKGEIDKMKKMTEQLKRGNDSKPSLSLPRKAKDRRWVSVSVGTEGPGTGSVACQTDLGVESTDHVKKLPLTVPAKPAAGSPLVAASAKGSGGATAPLARPGVDRQASHADLIVSSPPTIPPPNTNKIEENGPSTSSGPDTPSSTAPLPSNAAPPAIQTPNAAAQNYPAQAPSTHTVHSPCANAALHPALTPRVQAVRFRFQGNANNDQDQNGNNTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQAGAPPRPGAPPTGEGSTHPPVGRTSLKTPGAARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVLLDSSRASNAGPKVDHKTVALPPTSVPQGNRVINEESLPKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGAWRAETPGLKPPACSDRPLVIPTTIAFRCPINPVSASSCRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINHSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADNDGFTPVCAAAAQGHVKCVELLVAYHANINHAAAEGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGWTPVHAAVDTGSVDGLKLLLYHRAPACGDGLDTEASRLGVFDLDEGEANPESTPTPVIPADLINHANREGWTAAHIAASKGFKNCLKILCRHGGLEPERKDKCNRTVHDVATDDCKHLLENWNALKIPLRISVGETQGDNSGPDEFESEHTICALNIRKPTSWDDFSKAVSQALTSHFQAISSDGWWSLEDVTLNSPAEASIGLSATSVLSITLGNVPWSVGQSFTQSPWDFLRKHQAEQVTVLLSGPQEGCLSSVTYASMIPLPVLQNYLRLVEQYHTVIFHGPEGSLQDYIALQLALCMKHRQAAVGFSCDIVRADVDAGFSKEQLVDLFIKSACLIPAKQSPASKKTIIILENLERASLSELLGDFLAPLENRSPESPYTFHKGNGTSECYYFHENCFLVGTIAKACLQGPDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFRGKLPSPGEPVCKMVDWALSVWRQLNSCLSHLGTPEALLGPKCFLSCPVVPGHAQATVKWMSKLWNAVIAPRVQDAILSRASVNRQPGLGQTAAKKHPSPGQQAVVKAALSILLHKAVLHGCPLPRAELDQSMADFKGGSFPLSLVSSYSSCSKKKGENGAWRKVSTSPRKKSGWFFSPTWSKPDLSDEGIKSKTISQPNCNRNASLSRQKCLENDLSLALNLDQRLSLGSDDEADLVKELQSMCSSKSESDISKIADTRDDLRRFDSSRNRPAPSATVTNPRMPVSQKEVSPLSSHQTMERSNRTLKTELGVSRVKSFLPVPRSKITQCSQNTKRSSSSSNTRQIEINNNSKDEIWNLRNNEQIEKPNQ
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.
Protein: MYH7B_MOUSE
Sequence: MMDMSELGESACYLRQGYQEMMKVHTVPWDGKKRVWVPDEQDAYVEAEVKTEATGGKVTVETKDQKVLTVRETEMQPMNPPRFDLLEDMAMMTHLNEAAVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTAAVVAAYKGKRRSEAPPHIYAVADNAYNDMLRNRENQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPTGKLASADIDSYLLEKSRVIFQLPGERGYHVYYQILSGKKPELQDMLLLSMNPYDYHFCSQGVTTVDNMDDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFPKASDASFRAKLYDNHSGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDSFLVLHQLRCNGVLEGIRICRQGFPNRLLYADFRQRYRILNPSAIPDDTFVDSRKATEKLLGSLDIDHTQYQFGHTKVFFKAGLLGILEELRDQRLAKVLTLLQARSRGRLMRLEYQRMLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALATAEAKRQELEETQVSVTQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEAKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDEAVVRLTKEKKALQEAHQQALGDLQAEEDRVSALAKAKIRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQETVTDTTQDKQQLEEKLKKKDSELSQLNLRVEDEQLVGVQLQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAVLRHEATVAALRRKQADSAAELSEQVDSLQRIRQKLEKEKSELRMEVDDLGASVETLARGKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTENGELGRLLEEKESMISQLSRGKTSAAQSLEELRRQLEEESKAKGALAHAVQALRHDCDLLREQHEEESEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQREARGLGTELFRLRHSHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKAKKALEGEKSELQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECTNLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQAMEAQAATRLLQAQLKEEQAGRDEEQRLAAELREQGQALERRAALLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEVDLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELVYQTEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQASTNLAKYRKAQHELDDAEERADMAETQANKLRARSRDALGPKHKE
What is the function of this protein?
Involved in muscle contraction.
What are the official names of this protein?
Myosin-7B, Myosin cardiac muscle beta chain, Myosin heavy chain 7B, cardiac muscle beta isoform.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: FIXB_ESCF3
Sequence: MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGALAIQFGANHVWKLSGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASAVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVAWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAAFAR
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: TSAD_VIBA3
Sequence: MRIIGIETSCDETGIAIYDDEQGLLSHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIKAALAEANLTSKDIDGVAYTAGPGLVGALLVGATIGRSIAYAWGVPAVPVHHMEGHLLAPMLEDNPPPFPFVALLVSGGHTMMVEVKGIGEYRILGESIDDAAGEAFDKTAKLMGLDYPGGPLLSRLAEKGTPGRFKFPRPMTDRPGLDMSFSGLKTFAANTIRANDNDDQTRADIAYAFQEAVCATLVIKCKRALVETGMKRIVIAGGVSANKQLRVELEALAKKIGGEVYYPRTEFCTDNGAMIAYAGMQRLKNGETADLSVHATPRWPIDQLEPIV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR608_MIMIV
Sequence: MSKNNRKSPSESATLFKVGTIATGNDKNKWIVKETSNGVKRWTKFIPNSNIKIRNNELVSFNFNFIEKLFPKQTKHIGDIFINSNKIGVGELLFWPMNTQKGLYNIFNLKGCLIAVHNNVSLFDQKFTISDKFADCDIGMFSFNDYVNIEPYLQKNKIKKSSGFGLKFPEFSTKHFSFTGSKPNYVYLEDLEDFVDDESESVTKLNDPIAVFVDNKFGDGSFPIYVGKNAFFIMNPDVMDIMINNQ
What are the official names of this protein?
Uncharacterized protein R608.
Protein: RL13_HALSA
Sequence: MSLAEFDADVVVDARDCIMGRVASNVAERALAGDRVAVVNAEQAVITGTEDDVFSTYRTRANLGSDRGPYYPKRPDGIFKRAIRGMLPYKQDDGREALDSVRVYVGNPMDEDGDVLDGTSLDRLSTIRFVTLSEVSEELGANVTW
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: VAN1_YEAST
Sequence: MGMFFNLRSNIKKKAMDNGLSLPISRNGSSNNIKDKRSEHNSNSLKGKYRYQPRSTPSKFQLTVSITSLIIIAVLSLYLFISFLSGMGIGVSTQNGRSLLGSSKSSENYKTIDLEDEEYYDYDFEDIDPEVISKFDDGVQHYLISQFGSEVLTPKDDEKYQRELNMLFDSTVEEYDLSNFEGAPNGLETRDHILLCIPLRNAADVLPLMFKHLMNLTYPHELIDLAFLVSDCSEGDTTLDALIAYSRHLQNGTLSQIFQEIDAVIDSQTKGTDKLYLKYMDEGYINRVHQAFSPPFHENYDKPFRSVQIFQKDFGQVIGQGFSDRHAVKVQGIRRKLMGRARNWLTANALKPYHSWVYWRDADVELCPGSVIQDLMSKNYDVIVPNVWRPLPTFLGTEQPYDLNSWMESQEALALAKTLDEDDVIVEGYAEYPTWRVHLAYIRDAEGDPNEAVDLDGVGGVSILAKAKIFRNGVQFPAFTFENHAETEAFGKMAKKMGYRVGGLPHYTIWHIYEPSDDDLKEIASREREKRRQSE
What is the function of this protein?
The M-Pol I complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins.
What are the official names of this protein?
Mannan polymerase I complex VAN1 subunit, M-pol I subunit VAN1, Vanadate resistance protein.
What is the protein family that this protein belongs to?
Belongs to the ANP1/MMN9/VAN1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Cis-Golgi (PubMed:9430634). Recycles between endoplasmic reticulum and Golgi (PubMed:11095735).
Protein: Y1278_STAHJ
Sequence: MDNNDYKKFYLIREDVLPESVVKTLKIKDALKNNPELSIYEAVKLFDLSRSAFYKYRETIFPVDEKMLDHREFTLILYVNDIVGMLAQVLNTVSKLQLSVLTIHQSVPMEEKATITLSLSAKDTTISIDEIIKALRNIEHVSKVELISMSM
What are the official names of this protein?
UPF0735 ACT domain-containing protein SH1278.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: ISPH_ALKOO
Sequence: MKVVVADHSGFCFGVEKAIDTAFKELEYKDSKDIYTLGPLIHNQQVISHLEENGIKVVSDLNSGKDGVVIIRSHGVPKDVYKDASEKKIDLVDATCPFVRKIQNIVEEYQKKGYHIVIIGDPSHPEVIGINGWCDNTAHIVKNEDDVHRIPFLDNLCIVAQTTISTSLYTELTAMIEQKSNNVLKFNTICSATRDRQNSARNLAKEVDVMIIVGGYHSSNTQKLVEICKQEKPDTTFHIETAGEIPMNILKNYESVGVTAGASTPKWIIDEVIDRINNL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: SYH_BIFLS
Sequence: MAKGASISGFPEWLPSERVVEQRVIDTLRKVFELNGFIGIETRAVETGASLLKKGETSKEIYLLSRLQEVGHESDTPIEERLGLHFDLTVPLSRYVVEHSGALAFPFKRWQIQKVWRGERPQEGRFREFVQADIDVIGAGDLPDHYEVELPLVMVSALEELRAYGLPKATVHANNRKLSEGFYRGLGLTDVEGVLREIDKLDKIGADEVARLLTETCGATEAQARACLELAELTASDGAELAAKFDALCESHGIAKDSEAYTLARQGLDTLAMIVDEAAAIRPGSVIADLKIARGLDYYTGSVYETFLDGAASLGSICSGGRYDNLASQGNRKYPGVGLSIGLSRLVSYMLHAAGAHANRVSPAAVLVAVWNEEDRPAANRIANQLRARGIATDVAPTAAKLGKQIKYADKLGIPYVWFPATAAEGAEGAEPAGDEVKNIVTGEQVAADCTSWEPDTVVAQQTVEI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.