PharMolix/UniProtQA huggingface dataset:
Protein: RSSA_URECA
Sequence: MSGSIDTLALKEEDVTKFLACASHLGANNVDFQMEQYVYKRRPDGTSIINVRKTWEKVLLAARAIAAIENPADICVISARPYGQRAVLKFAHYTGATPIAGRFTPGTFTNQIQTAFREPRLLVVTDPYTDHQPVTEASYVNIPVIALTNTDSPLKYVDIAIPCNNKSIHSVGLMWWMLAREVLRLRGTISREVPWEVMVDLFFYRDPEEAEKEAQAEQAAAEKDKAPKEEFTADQAFTAPGTEVSDWASEVPVAPVPILAGGVDAATTEDWSVPAQSDWTAPAANPANAAAAGAPAPAPAAATTTESWGGSGAENWG
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA, Laminin-binding protein p40, LBP/p40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_DEBHA
Sequence: MIWTDVPTPWGMRFQDAATPNAEGMHELYDHMMYYLALMLGLVSYMLYVMMKDYKNNTFAYKYIKHGQTLEIMWTMFPAVMLLLMAFPSFMLLYLCDEVLTPAMTVKVVGLQWYWKYEYSDFVSETGETVEYESYVMPEDMLEEGQLRLLDTDTSMVVPVDTHVRFMVTANDVLHCFTMPSLGIKVDACPGRLNQVSALMQRTGVYYGQCSELCGVNHGLMPIKTECVPIGDFVEWLGEQENVYVA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS8_ACIBS
Sequence: MSMQDTVADMLTRVRNAQMAKKQTVSMPSSKLKVAIANVLQQEGYISNVEVAQEETKSTLTITLKYFEGKPVIEMVKRVSRPGLRQYRGKDKLPSVKQGLGIAIVSTSKGIMTDRAARAAGIGGEVIAFVS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: YBEY_ACIBS
Sequence: MKISLSLQQDFQSPELELKRAQLKKIIETTLRHVGYKEDCEIGIACVDLEESHQLNLQYREKDKPTNALSFPSDIPEEVLPMLDALPLGDLVICIPVVLQEALEQKKTAQNHFAHLLVHGVLHLLGYDHETSDEDAEEMEGLEIEILAKLNIANPYQE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNS1_ARATH
Sequence: MKILLASLCLISLLVILPSVFSASSSSEDFDFFYFVQQWPGSYCDTQKKCCYPNSGKPAADFGIHGLWPNYKDGTYPSNCDASKPFDSSTISDLLTSMKKSWPTLACPSGSGEAFWEHEWEKHGTCSESVIDQHEYFQTALNLKQKTNLLGALTKAGINPDGKSYSLESIRDSIKESIGFTPWVECNRDGSGNSQLYQVYLCVDRSGSGLIECPVFPHGKCGAEIEFPSF
What is the function of this protein?
May remobilize phosphate, particularly when cells senesce or when phosphate becomes limiting.
What are the official names of this protein?
Ribonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: CSRA_ALKMQ
Sequence: MLVLSRKNNESIMLGKDIEIKILGIEDGKVKLGIEAPKDVEIYRKEIYLEIQEENKAASEQKQDWSQLKGLFTKK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOPH_FUSV7
Sequence: MTLNLAEYDVLVFDIEGTVCPISFVKDVLFPYALEALPKVLDQEWDSPEFAKYRDAFPEEYRNSRPDFEAHVRDLVKRDVKIAYLKSLQGYLWLQGYKSGDIVAPLFPDVDPFFNQAVKDGKKIIIYSSGSVPAQKLLFSHTNSEKSDMTPLIADYFDTTNAGPKTEVDSYRKIISSHPEHKDLGRWLFLSDNIHEVSAAVEAGIRSVPVIRDGNAPLPPDNSLTKLAISEFKHSEDA
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DHSO1_YEAST
Sequence: MSQNSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGRYNLCPHMAFAATPPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDAAKAYDYNIAHGGEVVKTIIFGPE
What is the function of this protein?
Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols.  Is active with D-sorbitol (D-glucitol) and xylitol as substrates, leading to the C2-oxidized product D-fructose and D-xylulose, respectively.  Is likely involved in the utilization of D-sorbitol as a sole carbon source for growth.  Has no activity on mannitol and primary alcohols such as ethanol.
What are the official names of this protein?
Sorbitol dehydrogenase 1, SDH 1, Polyol dehydrogenase, Xylitol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RLMN_SPHAL
Sequence: MQIPGHIDPVTTGTVPLRGGNRIDLVGLSRDAIGGVLVEAGLDAKAAKLRAKQIWHWIYHRGVTDFMGMTDIAKAMRPWLTDRFIIGRPTVREAQVSSDGTRKWLLAAADGQEYEMVFIPDADRGTLCVSSQVGCTLNCRFCHTGTMRLVRNLGAGEIVGQVLLARDALGEWPKGNMAGFGAGSDADPEDDDADDDAVGHYTADGRMLTNIVMMGMGEPLYNFDEVKAALKIVMDGDGLALSKRRITLSTSGVVPMMARAGEEIGVNLAVSLHAVSKEIRDEIVPLNRKYGIEELLQACADYPGANNARRITFEYVMLKDKNDRDEDARELVRLIKQYKLPAKVNLIPFNPWPGAPYECSTPERVRAFSNLIFKAGISAPIRTPRGRDIMAACGQLKSAATRPTRAELDRIAEEKQAALG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1765_COXBR
Sequence: MTIYRFFKRSAFTLAYIYRRFHEEGCAYRATALAYTTLLALVPLTIVAFTLLSFVPAFQGVGVRLQNLIWENFVPTSAGMVAAYLSQLTQNVTGLSIINIFFLGIVALLLMYNINRAFVAIWHTEHHFRLSLHFLIYFMVLLLSPFLLGAVMLLGTFLVQSPLVTDLIGWPYLGKGLLFVLPYVLIFITFTLFNWVLPSAKVKLSHAVIGGLVTTVLFELAKFAFTVYLKFFPTYRVIYGALSVIPIFLVWLYVSWTIILLGAVVSNVIACGIPEKYK
What are the official names of this protein?
UPF0761 membrane protein COXBURSA331_A1765.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSGN1_MOUSE
Sequence: MDNLGETFLSLEDGLDSSDTAGLLASWDWKSRARPLELVQESPTQSLSPAPSLESYSEVALPCGHSGASTGGSDGYGSHEAAGLVELDYSMLAFQPPYLHTAGGLKGQKGSKVKMSVQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQTLKYTIKYIGELTDLLNSSGREPRPQSV
What is the function of this protein?
Involved in specifying the paraxial, but not dorsal, mesoderm.  May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation.
What are the official names of this protein?
Mesogenin-1, Paraxial mesoderm-specific mesogenin1, pMesogenin1, pMsgn1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBSD_SALAR
Sequence: MKKGTVLNSEISSVISRLGHTDTLVVCDAGLPIPNSAARIDMALTQGVPSFMQVVDVVTREMQVEAAILATEIKQQNPQLHETLLTHLEQLQQYQGNTIKISYTTHEQFKKLTADSQAVIRSGECSPYANVILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C1QBP_BOVIN
Sequence: MFQLLRCVPRVLGTAVAGLRAAAPSLPRLQPASRPCARPFGLLSVRARSVQLPGLLKPRGPCACGCGCSGLHTEGDKAFVDFLSDEIKEEKKIQKYKSLPKMSGGWELEVNGTEAKLVRKVAGEKITVTFNINNSIPPAFGGEEEEPSQGQKAEEQEPELTSTPNFVVEVTKDGSSKALVLDCHYPEDEIGQEDDQSDIFSIKEVSFQATGESDWKDTNYTLNTDSLDWGLYDHLMDFLADRGVDNTFADELVELSTALEHQEYISFLEDLKGFVKSK
What is the function of this protein?
Is believed to be a multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, protein synthesis in mitochondria, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing.  At the cell surface is thought to act as an endothelial receptor for plasma proteins of the complement and kallikrein-kinin cascades.  Putative receptor for C1q; specifically binds to the globular 'heads' of C1q thus inhibiting C1; may perform the receptor function through a complex with C1qR/CD93.  In complex with cytokeratin-1/KRT1 is a high affinity receptor for kininogen-1/HMWK.  Can also bind other plasma proteins, such as coagulation factor XII leading to its autoactivation.  May function to bind initially fluid kininogen-1 to the cell membrane.  The secreted form may enhance both extrinsic and intrinsic coagulation pathways.  It is postulated that the cell surface form requires docking with transmembrane proteins for downstream signaling which might be specific for a cell-type or response.  By acting as C1q receptor is involved in chemotaxis of immature dendritic cells and neutrophils and is proposed to signal through CD209/DC-SIGN on immature dendritic cells, through integrin alpha-4/beta-1 during trophoblast invasion of the decidua, and through integrin beta-1 during endothelial cell adhesion and spreading.  Signaling involved in inhibition of innate immune response is implicating the PI3K-AKT/PKB pathway.  Required for protein synthesis in mitochondria.  In mitochondrial translation may be involved in formation of functional 55S mitoribosomes; the function seems to involve its RNA-binding activity.  May be involved in the nucleolar ribosome maturation process; the function may involve the exchange of FBL for RRP1 in the association with pre-ribosome particles.  Involved in regulation of RNA splicing by inhibiting the RNA-binding capacity of SRSF1 and its phosphorylation.  Is required for the nuclear translocation of splicing factor U2AF1L4.  Involved in regulation of CDKN2A- and HRK-mediated apoptosis.  May be involved in regulation of FOXC1 transcriptional activity and NFY/CCAAT-binding factor complex-mediated transcription.  May play a role in antibacterial defense.
What are the official names of this protein?
Complement component 1 Q subcomponent-binding protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the MAM33 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cell membrane; Peripheral membrane protein; Extracellular side. Secreted. Cytoplasm. Nucleus, nucleolus. Note=Seems to be predominantly localized to mitochondria. Secreted by activated lymphocytes.
Protein: PCKA_AGRRK
Sequence: MEQFGVRNPAIELDSIGLGAAASVRYNLLESHLYEEAIRRREADLTAHGALRALTGQHTGRSPKDKFVVRNAVTEDQIWWDNNKPMSPEHFALLHKDMLAHVHGKDLFVQDLIGGADHDYALPTRVVTEFAWHSLFIRNLLIRPERSALESFAPKLTIIDLPSFRADPERHGCRTETVIACDLVNGIVLIGGTSYAGEMKKSVFTVLNYLLPERGVMPMHCSANVGPEGDAAIFFGLSGTGKTTLSADPTRTLIGDDEHGWGENGIFNFEGGCYAKTIRLSAEAEPEIYETTRRFGTVLENVVLDEHGVPDLDDGSLTENTRSAYPLDFIPNASESGMTGHPETIIMLTADAFGVMPPIARLTPEQAMYHFLSGYTAKVAGTEKGVVEPEATFSTCFGAPFMPRHPTEYGNLLKELIARHGAGCWLVNTGWTGGAYGTGRRMPIKATRALLAAALKGDLDKAEFRIDPNFGFAVPVAVEGVDSAILDPRSTWADGQAYDAQAAKLVQMFVSNFAKFEDHVDGNVRDAAPGLRAAAE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_PARP8
Sequence: MNDSVKTSLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYGKYVVRSKKYHAHDEANTYNEGDLVEIQETRPLSKTKAWTVSRLVEAARII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: MUTS2_STAAU
Sequence: SLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRSKISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVANTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNIVEILKNADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYEKSLIEDAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: CDGT1_PAEMA
Sequence: MKSRYKRLTSLALSLSMALGISLPAWASPDTSVDNKVNFSTDVIYQIVTDRFADGDRTNNPAGDAFSGDRSNLKLYFGGDWQGIIDKINDGYLTGMGVTALWISQPVENITSVIKYSGVNNTSYHGYWARDFKQTNDAFGDFADFQNLIDTAHAHNIKVVIDFAPNHTSPADRDNPGFAENGGMYDNGSLLGAYSNDTAGLFHHNGGTDFSTIEDGIYKNLYDLADINHNNNAMDAYFKSAIDLWLGMGVDGIRFDAVKHMPFGWQKSFVSSIYGGDHPVFTFGEWYLGADQTDGDNIKFANESGMNLLDFEYAQEVREVFRDKTETMKDLYEVLASTESQYDYINNMVTFIDNHDMDRFQVAGSGTRATEQALALTLTSRGVPAIYYGTEQYMTGDGDPNNRAMMTSFNTGTTAYKVIQALAPLRKSNPAIAYGTTTERWVNNDVLIIERKFGSSAALVAINRNSSAAYPISGLLSSLPAGTYSDVLNGLLNGNSITVGSGGAVTNFTLAAGGTAVWQYTAPETSPAIGNVGPTMGQPGNIVTIDGRGFGGTAGTVYFGTTAVTGSGIVSWEDTQIKAVIPKVAAGKTGVSVKTSSGTASNTFKSFNVLTGDQVTVRFLVNQANTNYGTNVYLVGNAAELGSWDPNKAIGPMYNQVIAKYPSWYYDVSVPAGTKLDFKFIKKGGGTVTWEGGGNHTYTTPASGVGTVTVDWQN
What are the official names of this protein?
Cyclomaltodextrin glucanotransferase, Cyclodextrin-glycosyltransferase, CGTase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: U79_HHV6Z
Sequence: MYAEERGYGSFDNVIQAYEQIISQSLHLKRFEFDNGCFIEFLADSGTCETFSKGWISMIYWTSETDSMGSLTVDIGMDEGKCRTYRARGLLLCSKSITSISQNTEGRERILTVSHENGKLQITFVTIAKVSSEPELRNLGDLKFMEKFEKECRALDRKKHDDEHRKRSGKQKEKRKVEDIDKKKEDEKRKQEEKKRNDEDKRPDKKDEFDEPPKEKRQKSHHETKRNLEEQSHEDGIAPTSTTFVNGAVEGALSPCVSIDNHEDQQHDELDKRVYAQGTNREGLSNEDNYGNFQLNKSLEQLRARLVASSGEVVERSLSKLKERLDYVKDNLIKNVLECADVTVPSKCLSKTKHIEQKKQIVFSDCVRSVPVCEIKPFIDMRVFETETTQNARRVRQRTRTTVGSTDGAIGQQRVISGQNRGRARGRGRGRVPRRRNSNLNNLRTQNSAIVIDDSSETENFENAGSFNEDLLATTILETL
What is the function of this protein?
May be involved in DNA replication.
What are the official names of this protein?
Protein U79.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U79/UL112 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PNP_PROMA
Sequence: MQGQTTSVSFDGREIRLTTGRYAPQAGGSVLIECGDTAVLVTATQGQGREGADFLPLSCDYEERLYAAGRIPGSFMRREGRPPERATLISRLIDRPLRPLFPNWMRDDIQVVATCLSLDERVPADILAVTGSSMATLLAGIPFYGPMAAVRVGLLGDDFVLNPSFREIERGDLDLVVAGTPDGVVMVEAGSNQLTEQDVIEAIDFGYEAVNELIKAQESILKDSGLTQIKPEKPDLDETVPSYLEKNCTKPISALLKEFDLSKEDRDLKLDEIKTNCAEKIDSLKDDNAVKKSITTNTKLLGISFKALTKKLMREQIIKDGKRVDGRALDEVREISAEAGILPKRVHGSGLFQRGLTQVLSTATLGTPSDAQEMDDLNPSPDKTYIHHYNFPPYSVGETRPMRTPGRREVGHGALAERAIIPVLPPKESFPYVLRVVSEVLSSNGSTSMGSVCGSTIALLDAGVPLKAPVSGAAMGLIKEGEEVRILTDIQGIEDFLGDMDFKVAGTEKGITALQMDMKMTGLPIKIIGEAINQAKPARTHILEKMVQAIDKPRETLSPHAPRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIEDGGIVTIASHDGVAAEEAQKIIEGLTRKVHEGEVFTGSITRIIPIGAFVEILPGKEGMIHISQLSEARVEKVEDVVKVGDEVTVRVREIDNRGRINLTLRGIPQNGDMQYYPQPTPTPVAPLM
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCF1_ECOLX
Sequence: MDARKNGVLITGGAGFIGKALITEMVERQIPLVSFDISDKPDSLPELSEYFNWYKFSYLESSQRIKELHEIVSRHNIKTVIHLATTMFPHESKKNIDKDCLENVYANVCFFKNLYENGCEKIIFASSGGTVYGKSDTPFSEDDALLPEISYGLSKVMTETYLRFIAKELNGKSISLRISNPYGEGQRIDGKQGVIPIFLNKISNDIPIDIIGSIESKRDYIYISDLVQAFMCSLEYEGHEDIFNIGSGESITLKKLIETIEFKLNKKAVIGFQDPIHTNANGIILDIKRAMAELGWRPTVVLDDGIDKLIKSIRCK
What is the function of this protein?
Catalyzes the stereospecific reduction of the C-4 keto group of dTDP-4-dehydro-6-deoxy-D-glucose, leading to dTDP-D-fucopyranose.  This is a step in the biosynthesis of D-fucofuranose, a component of E. coli O52 O antigen.  Is more efficient using NADH than NADPH as cosubstrate.
What are the official names of this protein?
dTDP-4-dehydro-6-deoxyglucose reductase, dTDP-4-dehydro-6-deoxy-D-glucose reductase, dTDP-4-keto-6-deoxyglucose reductase, dTDP-6-deoxy-D-xylo-hex-4-ulopyranose reductase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: RRF_NOSP7
Sequence: MILADAKSKMQSSVESTQRAFNTIRTGRANASLLDKVLVDYYGSPTPLKSLANISTPDASTILIQPYERNTLNIIEKAISLSDVGLTPSNDGSVIRLNIPPLTSDRRKEFVKMATKYAEEGRVAIRNIRRDAIDSIRKQEKASEISKDESKDQQDNLQKLTNEYTSRIDALLAEKEKDITTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASPD_BURM9
Sequence: MRNAHAPVDVAMIGFGAIGAAVYRAVEHDAALRVAHVIVPEHQCDAVRGALGERVDVVSSVDALACRPQFALECAGHGALVDHVVPLLKAGTDCAVASIGALSDLALLDALSNAADAGGATLTLLSGAIGGIDALAAARQGGLDEVRYIGRKPPLGWLGTPAEAICDLRAMAAEQTIFEGSARDAAQLYPRNANVAATVALAGVGLDATRVCLIADPAVTRNVHRIVARGAFGEMSIEMSGKPLPDNPKTSALTAFSAIRALRNRASHCVI
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: SYFA_BORPA
Sequence: MRFEGSNSMTLLVDDLVSQAQERFAAASDAAALENAKARFLGKEGALTVLLKALGKLDPEQKREMGARINQAKQQIEALLNARRAALAQAELDARLASETIDVTLPGRGKAAGGIHPVIRTWERVEEIFRSIGFDVADGPEVENDWTNFTALNNPLDHPARSMQDTFYVDMHDADGLPLLLRTHTSPMQVRYARMHKPPIKVIAPGRTYRVDSGATHSPMFHQVEGLWIAEDISFADLKGVYTDFLRCFFESDDLVVRFRPSFFPFTEPSAEIDMMFTSGPNRGRWLEISGSGQVHPQVVRNFGLDPERYIGFAFGSGLERLTMLRYGVNDLRQFYEGDLRFLRQFNE
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_YERPN
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRDRSSLPTPHEIRHHLDDYVIGQEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIGQRINTGSGIGFGAVVKGQSEKATEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLSELSEDALIQILKEPKNALTKQYQALFSLEGVELEFRDEALTAIAKKAMARKTGARGLRSIVEGALLDTMYDLPSMDSVEKVVVDESVIAGQSAPMLIYGQPEAQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SYYC_XENLA
Sequence: MGDSLTLEGKAQLITRNLQELLGEDKMKEILKERPLRIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWDLLELRTRYYEQVIQAMLQSIGVPLERLRFIRGTEFQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKYLPALGYAKRIHLMNPMVPGLTGAKMSSSEEESKIDLLDSPADVKKKLKKAFCEPGNVENNGVLSFVRHVLFPLKSEFVVLRDEKFGGNKTYTDFETLEKDFAEELVHPGDLKASVEKALNKLLHPIREKFNSPEMKKLSNDAYPDASKQKSVPKGSTKNSGTEEIDPSLLDLRVGKILSVSQHPDADSLYVESVDVGEANPRCVVSGLVQYVPSDQLLGRSVVLLCNLKPQKMRGIESQGMLLCASTEGEQKQVEPLDPPSGSAPGERIYIEGYENGEPEGELKPKKKVFEKLQVDFRISDDLCAQWKGKNFLTKLGSVTCKTLRGGSIG
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, cytoplasmic, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.