PharMolix/UniProtQA huggingface dataset:
Protein: RNC_MYCPN
Sequence: MKNKKDKTQKPKVIDEKFVAFFKSLNIEPQNWQFYEDAFVHSSYVNENEDARASYDRLEFLGDALIDFIVAKKLFELYPNYNEGMLTRTKIEIVKGENLNRIGKELNFGNFIKLGKGMPYTETLFGDVLEALVAAIYEDLGIEKANQFVEEHIFKKTYSEILKYNFFSLFQEQKLPEPRVRVSLTSNNLVLSIIELNGDIIWSQAVPNSKHYDDKSVLEHNAMSAFTQFLKSGKGINFFSDIKNKLDSQKPMRALTVRPKKINWKARKPKLKALKNKVKADS
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPQ_ECOK1
Sequence: MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPNSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: PDRP_BACC3
Sequence: MDNKIVYVVSDSVGETADLVVRAAMGQFPFAPDIRRVPYVEDTGTLKEVISIAKSNQALICFTLVKPDMRQYLVTEAAKEGVEAYDIIGPLIDQIEEITGRVPRYEPGVVRRLDEEYFKKIEAIEFAVKYDDGRDARGILKADIVLIGISRTSKTPLSQYLAHNKRLKVANVPLVPEVDPPEELYQVAKEKCFGLKITPEKLNHIRKERLKSLGLSDGATYANINRIKEEIDHFENVVSKINCQVIDVSNKAIEETANIIVNAVQNQKMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: COCH_CAVPO
Sequence: MPAAWMPVLRLGAYASRVPGPAGGDGAVPIAITCFTRGLDIRKEKADVLCPAGCPLEEFSVFGNIVYASVSSICGAAVHRGVISISGGPVRVYSLPGRENYSSVDANGIQSQTLARWSASFTVTKGKSSTQEATGQAVSTARPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTADTGMRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVAFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCSHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRSIRYMSGGTATGDAISFTVRNVFGPVRDSPNKNFLVIITDGQSYDDVRGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDIIRGICRDFLESQQ
What is the function of this protein?
Plays a role in the control of cell shape and motility in the trabecular meshwork.
What are the official names of this protein?
Cochlin, COCH-5B2.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: PLP1_SCHPO
Sequence: MTSFPASHGFGPRKRGYQMDLTNVQPVENKPAWISMKSPLEKEIANEYEALKVTERKEDTQDYNEPELHNSNDPTVDLYADTYATQAATESDSELEDALFSQLDEFDDTAYREQRLEMLKKEFARVEAAKEKGHMQFLTVENEREVMDFTLSSKKVVIHFYHPDFIRCKIIDSHLEKIAKVHWETKFIRIEAANAPFLVVKLGLKVLPAVLCYVNSQLVDKIIGFADLGNKDDFETSLLEFRLLKSSAIDRLKEESSSNKSIYHDELQNNQSDDSDFFE
What is the function of this protein?
Inhibits early G-protein signaling events following pheromone stimulation.  May help create heterodimerizable beta-tubulin by facilitating the efficient transfer of nascent beta-tubulin polypeptides to the folding apparatus (By similarity).
What are the official names of this protein?
Thioredoxin domain-containing protein plp1, Phosducin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CDT1_MISSI
Sequence: MYNAPSAQEMSYSDHVQRRHEEKGCLYACVFTALCCFCCYETCECCLDCLCCCCS
What is the function of this protein?
Confers resistance to heavy metal ions (e. g.  cadmium (CdCl(2)) and copper (CuCl(2))) by chelating them at the plasma membrane of root cells, thus stopping their entry and reducing their accumulation.
What are the official names of this protein?
Protein CADMIUM TOLERANCE 1, Cd tolerant 1, MsCDT1.
What is the protein family that this protein belongs to?
Belongs to the CYSTM1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Secreted, cell wall.
Protein: SEPT7_RAT
Sequence: MSVSARSAAAEERSVNCSTMAQPKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQGHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEEEKANWEAQQRILEQQNSSRTLEKNKKKGKIF
What is the function of this protein?
Filament-forming cytoskeletal GTPase.  Required for normal organization of the actin cytoskeleton.  Required for normal progress through mitosis.  Involved in cytokinesis.  Required for normal association of CENPE with the kinetochore.  Plays a role in ciliogenesis and collective cell movements.  Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity).
What are the official names of this protein?
Septin-7, CDC10 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Note=Distributed throughout the cytoplasm in prometaphase cells. Associated with the spindle during metaphase. Associated with the central spindle and at the cleavage furrow in anaphase cells. Detected at the midbody in telophase (By similarity). Associated with actin stress fibers. According to PubMed:15485874, also found in the nucleus. Found in the sperm annulus (By similarity).
Protein: XYLG_PECAS
Sequence: MPHLLEMKNITKAFGAVKAVDNVSLTLEAGQVLSLCGENGSGKSTLMKVLCAIYPHGSYDGQIIFSGDELRANHIRDTEQKGIAIIHQELALVKEMTVLENMFLGNEWTRFGVMDYDNMYLRCQRMLEQVKLAVDPNTKVGELGLGQQQLVEIAKALNKQVRLLVLDEPTASLTERETGILLEIIQDLRDHGIACIYISHKLNEVKAISDVICVIRDGKHIGTRPAAELSEDHIIAMMVGRELTELYPNEPHVIGEEVLRVEHLTAWHPVNRHIRRVDDVSFALHRGEILGIAGLVGSGRTETVQCLFGAYRGRWQGDIFIDGKPVTISNCQQAMAQGIAMVPEDRKKDGIVPVMGVAQNMTLAALDQFTGPLSMLDDAREQDIIRQSLANLKVKTSSPELAIARLSGGNQQKAVLAKCLLLNPRILILDEPTRGIDIGAKYEIYKLINALVKQHIAVIVISSELPEVLGLSDRVLVMHQGRIKADLINRDLTQEQVMEAALRSEHRAENIAV
What is the function of this protein?
Part of the ABC transporter complex XylFGH involved in xylose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Xylose import ATP-binding protein XylG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ILVD_BLOPB
Sequence: MPKYRSITTTHGRNMTGARALWRATGMTTEDFDKMIIAVVNSFTQFVPGHIHLRNVGALVSEQINITGGVAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSVEYMINAHCVDAMVCISNCDKITPGMLMAALRLNIPAIFVSGGPMESGAITLSNQNVKLNLIDAITCSVDPNISDVDQQRIESAACPTCGSCSGMFTANSMNCLTEALGLAQPGNGSLLATHSDRKKLFLNAGKYIVHLAKSYYEENNYSVLPRNIANKSSFENAMMLDIAMGGSTNTVLHLLAAAQEGEIDFTMADIDKLSRKVPHLCKVAPNTQRYHMEDFHRAGGVMGVLGELHRCGLLHEDTRNILNKSLLETLLNYDIFSCDNFESKNMYAAAPAGIRSTQAFIQKNRWTSLDTDRRSGCIRSREHAYSQDGGLAVLYGNLAVDGCLVKTAGVHINLQKFSGPAKVYESQEESVQAILTGNIHSGDVIVIRYEGPKGGPGMQEMLYPTSFLKSMGLDLCCALITDGRFSGGTSGLSIGHISPEAANKGLIGLVHDGDIINIDISMRSITLEVSEHILKIRHAAEIARGNKAWTPTNRNRNISISLKAYAHLVTSADKGAVRDKSKLLG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: MTNB_YERP3
Sequence: MTENRQLGALLAACHWIGEKGWCPATGGNMSLRLDLAHCLITESGKDKGSLAAEDFLLVETANNHVPSGRTPSAETGLHTLLYRLYPEIQAVLHTHSVNATVLSRVERSNALVLQGYEMQKSLSGQRSHLDAVVIPIFDNDQDIPALAQRVAAYADNRPLQYGFLVRGHGLYCWGNSVVEARRHLEGLEFLFQCELQRRLFDVNSNVDVKPNVDVNPNVEAK
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: TRMN6_VIBCH
Sequence: MKTNKLINKSFRFKQFSIEEGTCGMPISTDGVLLGSWAFSLSPTTILDIGCGTGLLSLMCAQRFPHAHITALDIEQTAYLAAEHNRQQSPWAERIECQHADILHWQPSKRFAAIICNPPYFNSGETAQHQVRATARHTISLQHQALIERLPQLLEPDGVASFILPKAEGEDFIALARQAGLFVGRYCQVQPTTDKPVHRLLFELHLSPCLPVETRLVIREQQGYSEAFCQLTRDFYLKMS
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_VIBVU
Sequence: MTQAFNERIAQALKQRREQGLSRQSEVIFSGNQTVLEHQGKRYLNFSANDYLGLANDQSLVRAWQQGLSLYGCGSGASPLVTGYTPAHSNLAASLCDWLGYESATLFGSGFSANQALLFALLEKGDLLVQDKLNHASLIEAGLLSPATMKRFKHNDLKALDTILNRSDCPSLVVTEGVFSMDGDCSPLAEMHALTQRHSASLMVDDAHGVGVLGEEGRGSCALASVKPDFLVVTFGKAFGLSGAALLTDKSSGDFLAQFARHHVYSTALPPAQAFALTHAVEMIRTQQWRRDKLNELQTLFAEYLGEHDSFVATQTPIKPWLIGETQQAVMVAQRCREQGIWLTAIRPPTVPQNTARLRITLSANHTKEQMHTLAQVLLTVTGEH
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: UCRI_HUMAN
Sequence: MLSVASRSGPFAPVLSATSRGVAGALRPLVQATVPATPEQPVLDLKRPFLSRESLSGQAVRRPLVASVGLNVPASVCYSHTDIKVPDFSEYRRLEVLDSTKSSRESSEARKGFSYLVTGVTTVGVAYAAKNAVTQFVSSMSASADVLALAKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTQKEIEQEAAVELSQLRDPQHDLDRVKKPEWVILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRLGPAPLNLEVPTYEFTSDDMVIVG
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).  UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer.  One of the fragments, called subunit 9, corresponds to its mitochondrial targeting sequence (MTS).  The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function.
What are the official names of this protein?
Cytochrome b-c1 complex subunit Rieske, mitochondrial, Complex III subunit 5, Cytochrome b-c1 complex subunit 5, Rieske iron-sulfur protein, RISP, Rieske protein UQCRFS1, Ubiquinol-cytochrome c reductase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: TPIS_ACTPJ
Sequence: MARRPLVMGNWKLNGSKAFTKELIAGLKAELADVKGCDVAIAPPVMYLAEAEAALAGQSVIALGAQNVDVNVQGAFTGDISTEMLKDFGAKYIIIGHSERRTYHKECDTFIAKKFAALKAAGLVPVLCIGETEAENEAGQTEAVCAKQIDAVIDALGVEAFNGAVIAYEPIWAIGTGKSATPAQAQAVHAFIRGHIAAKSQAVADQVIIQYGGSVNDANAAELFTQPDIDGALVGGASLKAPAFAVIVKAAEKAKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMA2_CAEEL
Sequence: MINFDGIKKITERLKWKQGDEDENWAKKAIDNLMKKLIKHNKQALENLEFALRCQGQQKTECVTIPRSLDGRLQISHRKALPHVIYCRVYRWPDLQSHHELKAIEDCRFCYESGQKDICINPYHYKRVHATGVLPPVLVPRYSEKPPQEVPPTLAKFQLMEMSGSRMPQNVNMANVNFTANQFHQYNPNGIEEMDTSQKFDIPPGVPTCLVPFDKVWEEQFWATVSYYELNTRVGEQVKVSSTTITIDGFTDPCINGSKISLGLFSNVNRNATIENTRRHIGNGVKLTYVRSNGSLFAQCESDSAIFVQSSNCNYINGFHSTTVVKIANKCSLKIFDMEIFRQLLEDCSRRGFDASFDLQKMTFIRMSFVKGWGAEYQRQDVTSTPCWIEIHLHAPLAWLDRVLSTMGPTPRPISSIS
What is the function of this protein?
Involved in TGF-beta pathway.  Plays a role in male tail tip morphogenesis (PubMed:21408209).
What are the official names of this protein?
Dwarfin sma-2, MAD protein homolog 1.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SECG_PYRFU
Sequence: MAKEKTTLPPTGAGLMRFFDEDTKAVKVTPKGALAIVLVFILIEVLLQIIGPRIFG
What is the function of this protein?
Involved in protein export.  The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex (By similarity).
What are the official names of this protein?
Preprotein translocase subunit SecG, Protein transport protein Sec61 subunit beta homolog.
What is the protein family that this protein belongs to?
Belongs to the SEC61-beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SCPB_BACC7
Sequence: MDRTEQKSIIEGLLFVSGDEGISPEQIAKVLEIEGNEVINILEEMQKECEGAHRGLQIVQYAKVYRFATKKEHASYYQKLIDIPTAASLSQAALETLAIVAYRQPITRTEMEEIRGVKTDKALQTLVSHLLIKEMGRAEGPGRPILYGTTKEFLDTFGLKTLDDLPPLSEENEQMNEADLFFGSLQEISK
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: SMG_ECO24
Sequence: MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNALLWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLETREMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: TTCA_LEGPH
Sequence: MSSNPSSVEKKLLHYTGKAIADFNMIQRGDRVMVCLSGGKDSFTLLTILNQLRIKSGNKFEIFAFTLDQAQPGWNDACLRQWLAEKSIPHEILTRDTYSIVKEKIPEGKTYCSLCSRLRRGIIYRYAEENGFNKIALGHHRDDLVRTLMMSILYNGDIRSMPPKLLSDNKKHIVIRPLCYVQEKDIITFASEQAFPIIPCNLCGSQENLMRKKVASLIDQLAIENPKVPSNMLHALQSLKPSQLMDQNFWNFKNLEDGLETTQSIQCEEVFNAQEFELEDEKI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_SALEP
Sequence: MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNQQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRITQLHYARQGIVTPEMEFIAIRENMGRERICSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: DUSC_SHEON
Sequence: MRVILAPMEGVVDDLMRDILSSINPYDLLVTEFVRVVDQLLPEKVFLKLCPELLSGGYTPSGTPVRVQLLGQEPNCMAENAMRAIELGSHGVDANFGCPAKMVNRSNGGAVLLQYPNTIHDIVRAMRQAVPAEHPVTAKIRLGYEDKSLFMENALAVYEAGATELAIHARSKVDGYKPPAYWEYITEVRERLPIPVIANGEIWNRDDAKRCMQVTGCDSIMIGRGAISLPNLADTIKTGATPYSWADTLQLMLSYTQRELSGRKSDYYPARIKQWFSYLNRQYPEADTLFRELRIYKTTEEIVRVLEQAQHHLNQ
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U16 in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(16) synthase, U16-specific dihydrouridine synthase, U16-specific Dus, tRNA-dihydrouridine synthase C.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusC subfamily.
Protein: FOLD_NEOSM
Sequence: MTQLIDGFRIAAGICESIATSVAHLRKNNGLVPSLRVIIVGENPASQVYVRSKQKKAESLGIDAETIALPKDTSEVELIRLVNSLNDDTSINAILVQLPLPPHINPTRIIESIDSKKDVDCFHPENVGRLALSKDALLKPCTPAGSLYLIKSALGDNLSGMDAVVIGRSNIVGKPMAMLLLHENCTITLTHSKTRNIQEKTRQADIVISAVGIPHFVKKDFIKPGATVIDVGMNKVDGKLVGDVDFEDVLQKVKFITPVPRGVGPMTIAFLMLNTVITTCLQNKLEHQEVIGTVIQKL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: TGT_CLOBJ
Sequence: MYKLLKKSGKARRGEFTTPHGVIQTPVFMNVGTLAAIKGAVSSMDLKEIGCQVELSNTYHLHLRPGDEVVKKMGGLHKFMNWDRPILTDSGGFQVFSLSKIRKIQEEGVYFNSHIDGRKIFMGPEESMRIQSNLASTIAMAFDECVENPAPREYVEKSVERTTRWLHRCKDEMNRLNSLPDTINNKQMLFGINQGGTYEDIRIEHAKTIAKMDLDGYAIGGLAVGESHEDMYRIIDAVVPHLPEDKPIYLMGVGIPSNILEAVDRGVDFFDCVLPARNGRHAHVFTKEGKINLLNAKFELDDRPIDEGCQCPACKHYTRSYIRHLFKAKEMLAMRLCVLHNLYFYNNLMEEIRDAIDGDYFKEYKERKLKEWGGRA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: KHPA_STRR6
Sequence: MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDVGRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK
What is the function of this protein?
The KhpA-KhpB complex stimulates or controls elongasome-mediated lateral cell wall biosynthesis.  It is not clear what is the function of the KhpA homooligomer in vivo.
What are the official names of this protein?
RNA-binding protein KhpA, KH-domain protein A.
What is the protein family that this protein belongs to?
Belongs to the KhpA RNA-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Some protein localizes to the division zone with FtsZ throughout the cell cycle, the rest remains in the cytoplasm.
Protein: HEM21_ARATH
Sequence: MATTPIFNASCSFPSTRGIDCKSYIGLRSNVSKVSVASSRIATSQRRNLVVRASESGNGHAKKLGMSDAECEAAVAAGNVPEAPPVPPKPAAPVGTPIIKPLNLSRRPRRNRASPVTRAAFQETDISPANFVYPLFIHEGEEDTPIGAMPGCYRLGWRHGLVQEVAKARAVGVNSIVLFPKVPEALKNSTGDEAYNDNGLVPRTIRLLKDKYPDLIIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVSQARAGADVVSPSDMMDGRVGAIRSALDAEGFQNVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALIEAREDEAEGADILLVKPGLPYLDIIRLLRDKSPLPIAAYQVSGEYSMIKAGGVLKMIDEEKVMMESLMCLRRAGADIILTYFALQAATCLCGEKR
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase 1, chloroplastic, ALADH1, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS16_RICTY
Sequence: MAVKIRLARGGAKKRPFYRVVIANATAPRDGDFLEKVGTYNPMLASDNSERVVLKKDRIEYWLSTGAKPTERVAKFIEKAGVTLPKNVKKEMEVKAKNRKVRPSKKESKES
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: CODY_STACT
Sequence: MSLLSKTRELNTLLQKHKGIAVDFKDVARKISEVTVTNVFIVSRRGKILGHSLNELLKSNRINQMLEDRHIPSEYTDKLIDVKQTVSNIGIDDDLSVFPPENRDTFIDSKTTIFPVLGGGERLGTLVLGRVSDDFTDNDLVLGEYAATVLGMEILREKHSEVEQEARDKAAINMAINSLSYSEREAIEHIFEELGGKEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGTFIKVKKEQFLDELEKSN
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.