PharMolix/UniProtQA huggingface dataset:
Protein: DNLJ_PSEAB
Sequence: MTDTQAAAERIAQLRTELDTHNYRYYVLDEPSIPDAEYDRLFRELQALETEYPQLLTPDSPTQRVSGTPASAFGEVRHEIPMLSLGNAFEEQDLLDFDRRVREGLADLLPGGDLLGGGAEVEYSCEPKLDGLAVSLLYERGQLVRGATRGDGSTGEDITSNVRTIRNVPLKLHGEGWPEILEVRGEVFMSKAGFEALNAKAVETGGKTFANPRNAAAGSLRQLDSKITASRPLEFCAYGFGQVSGTLPDTQVGILEAFRGWGIPISRELRLVKGAQACRDYYDDIGRRRDALAYEIDGVVFKVNRIAFQRELGFRAREPRWAIAHKFPAREELTELLGVEFQVGRTGAVTPVARLKPVQVAGVTVSNATLHNMDEVARLGLRIGDTVVIRRAGDVIPQVMQVVLERRPADAQAIEVPEHCPVCGSAVERTQLVKRSKGKESISEGAIYRCVGRLSCQAQLKQAIIHFVSRRAMDIDGLGDKIVEQLVDRGLVASPADLYTLTYEQVFELEGFAELSTNNLLAAIADSRKPSLARFIFALGIPDVGEETAKLLARSLGSLERIGKALPEVLTYLPDVGAEVAYEIHNFFADEHNRQVIAQLRDAEHGVQLQEEGEVAAEFAACASLAGFIDKLNIPFIAATGAEKLASRFGSLDGIIRADWLDLRQVERLPERAAKSLRDFFDEPANVQRALAIEAQLREFGMHWQSERKAVEGLPLAGQTWVLTGTLEAMSRDVAKDKLEGLGAKVAGSVSAKTHCVVAGPGAGSKLAKANELGVKVLDEDGLLKLFDEHGVAR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MURC_XANOM
Sequence: MIRRLQDSGDLVRAFPRVHFVGIGGTGMSGIAEVMLTLGYEVSGSDNSDNVATRRLAKLGARVMRGHSAANVLGTDCVVVSSAIRDDNPELMEARSQRIPIMPRAAMLAELMRFRRGIAVAGTHGKTTTTSLAAAVLSEGGLDPTFVIGGQLLAAGANAKLGGGQWLVAEADESDGSFLRLNPLMAVITNIDADHLENYGNDFARIQAAFAEFLQRLPFYGLSLLCIDDPEVAALAGRTPRHVMSYGMSENADVRAEDVVQDGPRMRFTLRLPEGTTTPVTLALPGRHNVLNALAAAAIGWQLGVAPGTIARALENFAGIGRRFNDLGEVTTSTGARVRVVDDYGHHPRELEAVFAAARGGWPDKRLVVAFQPHRYSRTRDQFDAFAAVLSTVDALVLSEVYPAGEAPIPGADSRALARAIRARGRSEPVVVGQIASLAEVLPDVLQDGDLLLMMGAGDIGYVAQHIINNGFVGEPA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_YERP3
Sequence: MATGKIIQVIGAVVDVEFPQDAVPKVYNALEVEGTTEKLVLEVQQQLGGGVVRCIAMGSSDGLSRGLKVTNLEHPIEVPVGKATLGRIMNVLGEPIDMKGPIGEEERWAIHREAPSYEELASSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEDDKLVVSRARKIQRFLSQPFFVAEVFTGSPGKFVSLKDTIRGFKGIMNGDYDHLPEQAFYMVGTIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y336_PARXL
Sequence: MRIILITGISGSGKSVALNALEDAGYYCVDNLPPRFLPQLASYLAEDGQDRLAVAIDARSSASLDEMPAMIRDLSRAHDVRVLFLNASTQSLIQRFSETRRRHPLSGSTSHDADVGLLNSLAEAIERERELVAGLAEFGHQIDTSNLRANVLRAWVKRFIEQKDSGLVLMFESFGFKRGVPLDADFVFDVRTLPNPYYDHELRPLTGLDKPVIDFLDALPVVHEMIDDIEKFLAKWLPHFRDDNRSYLTVAIGCTGGQHRSVFIAETLAARLAASANVIVRHRDAPVEAGESSKLVA
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Bxeno_A0336.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: SIX1_HUMAN
Sequence: MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNSVLLLQGNMGHARSSNYSLPGLTASQPSHGLQTHQHQLQDSLLGPLTSSLVDLGS
What is the function of this protein?
Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development (By similarity).  Plays an important role in the development of several organs, including kidney, muscle and inner ear (By similarity).  Depending on context, functions as transcriptional repressor or activator (By similarity).  Lacks an activation domain, and requires interaction with EYA family members for transcription activation (PubMed:15141091).  Mediates nuclear translocation of EYA1 and EYA2 (PubMed:19497856).  Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter and CIDEA enhancer (PubMed:27923061, PubMed:23435380, PubMed:15141091, PubMed:19497856).  Regulates the expression of numerous genes, including MYC, CCND1 and EZR (By similarity).  Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2 (By similarity).  Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex (By similarity).  During myogenesis, seems to act together with EYA2 and DACH2 (By similarity).  Regulates the expression of CCNA1 (PubMed:15123840).  Promotes brown adipocyte differentiation (By similarity).
What are the official names of this protein?
Homeobox protein SIX1, Sine oculis homeobox homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SIX/Sine oculis homeobox family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MAMA_MAGSA
Sequence: MSSKPSDILDEVTLYAHYGLSVAKKLGMNMVDAFRAAFSVNDDIRQVYYRDKGISHAKAGRYSQAVMLLEQVYDADAFDVDVALHLGIAYVKTGAVDRGTELLERSLADAPDNVKVATVLGLTYVQVQKYDLAVPLLIKVAEANPINFNVRFRLGVALDNLGRFDEAIDSFKIALGLRPNEGKVHRAIAFSYEQMGRHEEALPHFKKANELDEGASV
What is the function of this protein?
Probably forms a large homooligomer on which other magnetosome subunits assemble (Probable).  Required for formation of functional magnetosomes from pre-existing vesicles, it has a dynamic location in the cell (PubMed:15004275).
What are the official names of this protein?
Magnetosome protein MamA.
What is the protein family that this protein belongs to?
Belongs to the magnetosome MamA family.
What are the subcellular locations of this protein?
Magnetosome membrane; Peripheral membrane protein. Note=Reversibly binds to magnetosomes (PubMed:20439702). Forms oligomers that cover the surface of the magnetosome (PubMed:20439702). Its location is dynamic; in log phase cells tagged protein extends from one pole to the other, which is longer than the magnetosome chain and is occasionally associated with the inner membrane. In stationary phase it forms 3-4 spots in the cell (PubMed:15004275, PubMed:21784982).
Protein: ACPS_BACCN
Sequence: MILGIGIDIIELNRIEKMINGKLNFIERILTETERDVAAKLKGKRLVEFVAGRFAAKEAYSKAVGTGIGKEVSFLDIEIKNDQKGKPVLFTNTEYIVHLSISHSREFAVAQVVLESPSC
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALR3_HUMAN
Sequence: MARALVQLWAICMLRVALATVYFQEEFLDGEHWRNRWLQSTNDSRFGHFRLSSGKFYGHKEKDKGLQTTQNGRFYAISARFKPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPADIDQKNLNGKSQYYIMFGPDICGFDIKKVHVILHFKNKYHENKKLIRCKVDGFTHLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESKDWEQTKDNKAQDWEKHFLDASTSKQSDWNGDLDGDWPAPMLQKPPYQDGLKPEGIHKDVWLHRKMKNTDYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYADNFGKATWGETKGPEREMDAIQAKEEMKKAREEEEEELLSGKINRHEHYFNQFHRRNEL
What is the function of this protein?
During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3.  Required for sperm fertility (By similarity).  CALR3 capacity for calcium-binding may be absent or much lower than that of CALR.
What are the official names of this protein?
Calreticulin-3, Calreticulin-2, Calsperin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: MQO_MYCTO
Sequence: MSDLARTDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAAESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKAVRVNEQFQVTRQFWAYAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTEFIESPDEFARRLPFMAAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCVQNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFVGAGGDTLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAPPLGALHLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLSVLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQRVQVIRRDERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQKCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEVWSWSTKALKLGAA
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: PLSY_LEGPL
Sequence: MAFFIFLILVGYLMGSINSAIIVCRTFGLPDPREEGSKNPGATNVLRLGGKQYGIMVMVFDALKGILPVILAKLLSAEPVTVAFTALAAVVGHMYPVFFHFRGGKGVATTIGALLAFHFVIGVMVAATWLLVANFWRYSSLASIASISLAPFYSLILVGNLNIFPPLFMITILVLYKHRDNFNRLIDGKEPKIKFKHSVIEEIMEASPATSAEQEFPGKEVIDTNIDEAEKTEQAEAVKKPKAKKATTKAKKTTSKEETAKKPKSTKPKTKTVKEKE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYV_HELHP
Sequence: MESKAQEKQEQKKGYNPQDIESRFYAICEKRGYFEIEGNKSLWQGCAPKCFSIMMPPPNVTGVLHIGHALTFTLQDIITRFKRMEGFKTLYQPGLDHAGIATQNVVLKQLLAQGITKESLGREAFIAKVWEWKEQSGGEILNQMRHLGITPAWSRLRFTMDKGLQKAVKKAFVQWYNQGLIVQDNYMVNWCVNDGALSDIEVEYEQNHGKLYYLRYPIKDSAQSLIVATTRPETFFGDTGVMVNPNDERYKHLIGKSVILPLLGREIPIIADSHVDMSFGSGCVKVTPAHDMNDYEVGKRHNLPFITIFDEKGIFNKNAGIFQGQERLESRPLIVQKLQENGFVEKIEDYTNQVGKCYRCGNIVEPYISKQWFVKKETAHNAIQRVNNGELHFYPAQWLNNYNAWMRELKDWCISRQLWWGHRIPVWYCECGNKVASESDNPICPQCQSTITKQDEDVLDTWFSSGLWAFSTLGWGNEDTNTQPPLYHANDLAEFYPNSLLITGFDILFFWVARMILSGESLLDSLPFKDVYLHALVRDENGQKMSKSKGNIIDPMEIISSYGADTLRFTLAILCAQGRDVKLSTQSLEISKNFTNKLYNATNFLNMYLEQLGGKEALKKGFGDINHIHINTPLGQYMLVRFYTATNEVRAALENYRFNDGASILYRFLWGEFCDWGIELAKASKDSIYELGAIFKAALILLHPYMPFITDALWHTLNASDIQTSDSIMIHSYPKAMEKNEQHSQLERTFEVIQDVITSIRRLKAMLELGSTNIECIFVKLNAPFEHSLLEQFVCKLAKVKTLCITQQKPKDCVGDVSKYCECYIQLGEIDLQAIGTRLHNQRQKLEKEITKLQAMLGNENFIKNAPKAVMEQNQSALHNAQEKLDKINAELIALGLQS
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2072_VIBVU
Sequence: MIIYLHGFDSTSPGNHEKVLQLQFIDPDVRFINYSTLHPKHDMQHLLKEVHKAIEQSNDPEPIICGVGLGGYWSERIGFLCGIKQVIFNPNLHPENNMAGRIDRPEEYEDIATKCVEQFRMKNKGRCLVILSRDDEIHDNSKTAQALENYYEVVWDDKETHKFKKISQHLQKMKAFKENN
What are the official names of this protein?
UPF0227 protein VV1_2072.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: VP26B_HUMAN
Sequence: MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGKVSLALKNPNKRLEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTSLGEVRTPSQLSDNNCRQ
What is the function of this protein?
Acts as component of the retromer cargo-selective complex (CSC).  The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.  The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3.  The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling.  The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway.  The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins.  The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5.  May be involved in retrograde transport of SORT1 but not of IGF2R.  Acts redundantly with VSP26A in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1 (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 26B, Vesicle protein sorting 26B.
What is the protein family that this protein belongs to?
Belongs to the VPS26 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Early endosome. Late endosome. Note=Localizes to early and late endosomal structures (By similarity).
Protein: SYV_NATPD
Sequence: MSEVPDSYDPDEAEQKWRDEWLESDVYSYDGDEERPDYIIDTPPPYPTGNLHIGNALGWCYMDYAARYHRLQGDDVLFPQGWDCHGLPTEVKVEENRDIHRTDVSREQFREWCVEHTDEQIAAMKETMRTLGFSQDWDHEFRTMDDSYWQETQRSFLQMADSDYVYQDEHPVNWCPRCETAIADAEVENEDREGTLYYITFSGADNDDIEIATTRPELLPACVAIAVDPDDDRFEGRVGDRFEVPIFGQEVELIADDDVDGDFGTGAVMICTFGDKQDVDWWAEHDLDLRPVVTEDGHLNERAGEFEGRSIDEAKDEIATALSKSGHLHKEEPTEQSVGCCWRCDTPIEILSKEQWFVKVDQEEILETAQDIAWYPDHMYERLEEWTEGMEWDWVISRQRVFATPIPAWECADCGHIELADESEVPVDPTNDEPAVGSCPECGSDDWVGETDVMDTWMDSSISPLYVAGWPDETFEPVQLREQGHDIIRTWAFYTILRTAAVTDEIPWEEALINGMVFGDDGNKMSKSRGNFVQPEEVVEEHSADAFRQAMALGGQPGSDIQFQWKEVTSASRFQTKLWNITKFASEHIDESTPDIEAPAYRDADEWILARCARVADEVADDMDEYRFDSALRTVREFVWHDLADDYLELIKGRLYEGRPGERKAAEHALFVSLSASLRMLSPFAPFITEEAWSHLPADGSVHNAAWPDPPAGDEAAEERGELIAEVAATIRGWKSDEGKPLNADLERVEVYIDEDRPLDTYDLADTVNGPVYIEEGTPSVELVPVGVDIEHSELGPVFRDKAGEVVGRLESADPAELQAELDTDGHVEFEVDGETVTVEPEMFDIVEEQRAESGEEVVVLEADDATVLVFE
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK29_GRATL
Sequence: MPLPKIQDIQDFTDKEIEEKIIKLKKEIFDLKLKQATRQNVRSHLFKHKKHQLAQLLTIKKDSNYV
What are the official names of this protein?
50S ribosomal protein L29, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSCI_PSEAE
Sequence: MDISRMGAQAQITSLEELSGGPAGAAHVAEFERAMGGAGSLGGDLLSELGQIRERFSQAKQELQMELSTPGDDPNSLMQMQWSLMRITMQEELIAKTVGRMSQNVETLMKTQ
What is the function of this protein?
Component of the type III secretion (T3S) injectisome that translocates effector toxins into host cells, facilitating the establishment and dissemination of infection.  Polymerizes into flexible and regularly twisted fibrils and plays an essential role in needle assembly.
What are the official names of this protein?
Type III inner-rod protein PscI.
What is the protein family that this protein belongs to?
Belongs to the YscI/HrpB family.
Protein: UBIE_BORPA
Sequence: MQTPHSQPESAPQGEQSTHFGFQSVPEADKARKVAEVFHSVASRYDVMNDLMSAGLHRVWKAFTIGRAAVRPGMKVLDIAGGTGDLARAFAKRAGPSGEVWLTDINESMLRVGRDRLTDSGLLVPTAVCDAERLPFPSQYFDRVSVAFGLRNMTHKDRALAEMTRVLKPGGKLLVLEFSRVAKPLAPAYDWYSFNVLPWMGKKVANDEASYRYLAESIRMHPDQETLAGMLRDAGLDRVQYFNLTAGVAALHEGVRLG
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RL19_PONAB
Sequence: MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMKL_XANC5
Sequence: MKFFASCAKGLEYLLADELLALGASKATATISGVNVEGELRDAQRAVLWSRLASRVLWPLTEFDCPDEDALYAGVAELPWDAHLSVGHTLSVDAHVSGTAITHARYAAQRIKDAVVDTMRRQGLERPSVDVENPDLRLNLSLRKGRATISVDLGGGPLHRRGWRMAQNEAPLKENLAAAVLMRGGWPRAYADGGGLLDPMCGSGTLLIEGALMAADVAPGLQRYGSDVPSRWRGFDRESWQQLVSEARERDSVGRAALKQVIHGSDMDPHAIRAAKENAQVAGVAEAIWFGVREVGELQTPPQATGVVVCNPPYDERLAADAALYRRLGDTLQRVVPQWRASLLCGNAELAYATGLRAGKKYQLFNGAIECALIVCDPIAVPRRTPLAAPTALSEGAQMVANRLRKNLQKFKKWRAREGIECFRAYDADLPEYSAAIDVYQQADGDRRIFLHVQEYAAPATIPEADVRRRLNELLAAAREVFEVPAERVALKSRERGKGGSKYGRFEQRNEIVHVREHGALLRVNLFDYLDTGLFLDHRPLRGTMAQQSKGRRFLNLFCYTGVASVEAAVAGAASTTSVDLSATYLQWCAENLALNGLAGSKHKLMQADALAWLEAERAHFDVIFCDPPTFSNSARAEDFDIQREHVRLLRAAVARLALGGVLYFSNNFRRFKLDEEGVAEFAQCEEISPRTIDPDFERHARIHRAWRLTA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX121_LYCSI
Sequence: MMKVLVVVALLVTLISYSSSEGIDDLEADELLSLMANEQTRKECISKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1i, Toxin-like structure LSTX-A21.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRE_RHOPB
Sequence: MSKSASRARLADIIRARSFGRGEITLASGRKSDFYFNLKPTMLDPEGAALLAELTFEALREDNVDYIGGLEMGAVPLAGAIAQLSWLKNHPIAAFFVRKKPKEHGARLSVEGLSKTETLQGKRVVIVEDVTTTGGSAIKAAESVREAGGVIVLVLTMVDREEGATEAFAAAGLPFRSLYKASEFLKS
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: ODP1_PSEAE
Sequence: MQDLDPVETQEWLDALESVLDREGEDRAHYLMTRMGELASRSGTQLPYAITTPYRNTIPVTHEARMPGDLFMERRIRSLVRWNALAMVMRANKHDPDLGGHISTFASSATLYDIGFNYFFQAPTDEHGGDLVFFQGHASPGVYARAFLEGRISEEQLENFRQEVDGNGLSSYPHPWLMPDFWQFPTVSMGLGPIQAIYQARFMKYLESRGFIPAGKQKVWCFMGDGECDEPESLGAISLAGREKLDNLIFVINCNLQRLDGPVRGNAKIIQELEGVFRGAEWNVNKVIWGRFWDPLFAKDTAGLLQQRMDEVIDGEYQNYKAKDGAYVREHFFGARPELLEMVKDLSDEEIWKLNRGGHDPYKVYAAYHQAVNHKGQPTVILAKTIKGYGTGSGEAKNIAHNVKKVDVDSLRAFRDKFDIPVKDADLEKLPFYKPEEGSAEAKYLAERRAALGGFMPVRRQKSMSVPVPPLETLKAMLDGSGDREISTTMAFVRIISQLVKDKELGPRIVPIVPDEARTFGMEGMFRQLGIYSSVGQLYEPVDKDQVMFYREDKKGQILEEGINEAGAMSSWIAAGTSYSTHNQPMLPFYIFYSMFGFQRIGDLAWAAGDSRAHGFLIGGTAGRTTLNGEGLQHEDGHSHLLASTIPNCRTYDPTYAYELAVIIREGSRQMIEEQQDIFYYITVMNENYVQPAMPKGAEEGIIKGMYLLEEDKKEAAHHVQLLGSGTILREVEEAAKLLRNDFGIGADVWSVPSFNELRRDGLAVERWNRLHPGQKPKQSYVEECLGGRRGPVIASTDYMKLYAEQIRQWVPSKEYKVLGTDGFGRSDSRKKLRNFFEVDRHWVVLAALEALADRGDIEPKVVAEAIAKYGIDPEKRNPLDC
What is the function of this protein?
Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component, PDH E1 component.
Protein: ABCAB_DICDI
Sequence: MRHQNKNHKQRPSFLSQFLVILWFRTKLSIRDKKFFILGILLPMISIGASIILNNVLVFGPGSDFQKTNNNLNNNNIFITPKTLNSQQETLINTMKLQYSLNYTYLDDDTDLPNYIENKSLSSLDYGISFIGSNGINIYYNSSIESIPSFVHSFFISLFKINGINLQLNETITVLSSEVTFDAFYLLMPMILQYGFVFFIPYFAILIVTDRDKGFKNHLILNSLRTSVYWFGNLVFDYLIFLIPTIIGWILLYSFKIDGIYSDNSGKSFLLFLTFGISAIPFGFVLQFIFDKEETANKWLYPFTSIVTSIPSALISVAFPTSTPLIVELLLSILPTFSFCNGLKALTYNNSSTVSYTILIQLLSGLIYLILIYFIDNYKKPKKNEIINDEDSESIINNQIIEDNDVLNEKEKIKRLVRDGGGNNNNNKKNNSYPKIVVDGIYKQFIQPKPTLDKPSIIERCSGGTKATKKNSIIKKAVDGIWFSVEKNEIFGLLGPNGSGKSTCLNLLTGLLKADQGDGYLSGKSIDKDKDVFQSIGSCAQNDILFENLTIYEHLYLFSRLKSITTTKSELEDEIDFYINKFSIQSFKNKKSSDLSGGTKRKLSVACCLIGDPQVVLLDEPSTSLDPISRNELHSLIDELKVNKSIIMTTHSINEINQCCNRVAIMVDGKIRCIGTPNHLKHKYGSGYTIDIIPNNYLNNSYEIHNFMAQTFPNATRVERLGRFISYDLPSQNQQSLSTIFRILQSNKQRLQILDFSASSSSLEKVFLKFANLQEEINKQQTNNKSNIINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNTNNNQLIN
What are the official names of this protein?
ABC transporter A family member 11, ABC transporter ABCA.11.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: H2A1_PICST
Sequence: MSGGKGKAGSSEKASTSRSAKAGLTFPVGRVHRLLRKGNYAQRVGSGAPVYLTSVLEYLAAEILELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKSGKSAKASQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ATPH_OENGL
Sequence: MNPLISAASVIAAGLAVGLASIGPGIGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.