PharMolix/UniProtQA huggingface dataset:
Protein: GATB_ANAD2
Sequence: MPLSDFQVVIGLEVHAQLLTRSKIFCGCSTAFGGAPNAHTCPVCLGLPGALPALNRAVVEMAVRTGLALGCEIRPKSVFARKNYFYPDLPKGYQISQYELPICEGGEVTFTLEGRDHTARLVRIHMEEDAGKNVHDVSADGASGVDLNRAGVPLVEIVSRPDLRSAEEAVEYLKALRAILMALGVNDGNMQEGSLRCDANVSVMRKGASELGTRCEIKNMNSFRFLKQAIEFEARRQVELIEAGEPVVQETRLFDPDRGETRSMRSKEEAHDYRYFPEPDLPPVIVEAALVERIRGELPELPRARAERYQRRLGLSAYDAGNLVADAAVAAWFDAALGAYGAGPEAAKKVANWVTGELARLANETGEAPAAWKMTPARLAAVLRLVDAGTIGGPGAKQVVEEVFRTGAEPDAVVKAKGLAQVSDEGAIEAAVDKVLAANPGEAEKYRGGRKNLLGFFVGQVMKEMRGKGNPAVVNALLRRKLGD
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: C98A8_ARATH
Sequence: MIIYLISLLPIIVATLMLYQRWWRSNIPPGPKPKFLLGNLHQMKPLWTHSFSEWSETYGPIISVWIGSQLTVVVSSSDLARQVLRDKDHQLSNRHRIARMTQTGTDLVWSDYSPHYVKLRKLCTLELFSLKSIENFRSLREMEARSMVVSILKDLMSNSGDDQERKPVIVRKYLAAVVLNTISRLMIGKEFGSEEGKEFKAIVEKEHLLSGSGTILDHVWWLKWVSSWFFSDKEFLAHKDRRTKWFRGAIMVEEDIEIEDHRGFVRKLLVLKEQKELSEETVGGLVWNMLTAGADTTAVVIEWAMAEMIKCPTVQEKAQQELDSVVGSERLMTESDIPILPYLQCVVKEALRLHPSTPLMLPHKASETVWVGGYKVPKGATVYVNVQAIGRDPANWINPYEFRPERFLQEETDVKGRDFRVLPFGSGRRMCPAAQLSMNLMTLVMGNLLHCFSWSSPVPGERIDMSENPGLLCNMRTPLQALALPRAAARAIPLPLD
What is the function of this protein?
Acts redundantly with CYP98A9 as tricoumaroylspermidine meta-hydroxylase.  Catalyzes also the meta-hydroxylation of the three triferuloylspermidine phenolic rings.  Unable to use 5-O-(4-coumaroyl) D-quinate or 5-O-(4-coumaroyl) shikimate as substrates.
What are the official names of this protein?
Cytochrome P450 98A8, p-coumarate 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL24_RICBR
Sequence: MIKLKVKKGDEVIVITGKYKGKKGKILKVFPEQNKIVVSGINLVKKHTKPTKVSEGGIITKELPIDISNVAHVDPKTGNPTKVAFKFLEDGSKVRIAKKSGEIIGKEGK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SCPA_STRS2
Sequence: MDIKLKDFEGPLDLLLHLVSKYQVDIYEVPITEVIEQYLAYIATLQAMRLEVAGEYMLMASQLMVIKSRRLLPKVVEQIDPEDDPEMDLLDQLEEYRKFKLLSEKLGEQHDERANYFSKPKLDLIYDDVQLAKDKTVIDIFLAFSKVMAEKQASLRQSHATIARDEYKIEDMMDFVRSRFETGPRLELRQLFQESQDVNEMITIFLATLELVKVHEIVLEQTETFGDIYLVRSEDESLS
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: APAH_NEIMA
Sequence: MAHYAIGDIQGCFDELTALLGKIGFNHGTDTLWLTGDIVNRGPKSLETLQFCIRHENSVQIVLGNHDLHLLAVGYGEGAPKRSDTIEPILKHPDGRKMLDWLRAQPLLIREGNRVMVHAGILPQWRITKAESLAGEAEAELRGKKYVKFFSKMYGNKPAAWDEGLEGYARLRFIVNAFTRMRALTFKNELDFDYKSTVKKMPLYLRPWFKAPDRQNLDHTIIFGHWSSLGYTNADNVISLDTGALWGGQLTAVNLETEEITQVQAAGGIDWKSFTK
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: ARGP_YERPP
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENLFGQPLLVRTVPPRPTEQGQKLLALLHQVELLEEEWLGNDNGVDTPLLLSLAVNADSLATWLLPALKPVLADLPIRLNLQVEDETRTQERLRRGEVVGAVSIQPQPLPSCLVDQLGALDYLFVASKAFAERYFPNGVTRSALLKAPAVAFDHLDDMHQAFLQQNFDLSPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLLQRRMLFWHRFAPESRTMRKVTDALLSYGRQVLRQDSFIGQ
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: ERG3_ASHGO
Sequence: MDLVLEFCDSYFFDYVYATLLPASLSPKMGGTWQQAMIKEQMVNATRVFGRSLERPLEVYGYAPFMFEVSPHAFGSVLPRYSLLRQSLSLFLVTTVFGWLLYLIVASFSYVFVFDKSVFNHPRYLKNQMSMEIKQGLGAIPYMAVMTVPWFLLELHGYSHLYMGLELNVRGYVRLALEALFFILFTDFGIYLLHRWLHWPAVYKVLHKKHHKWLVCTPFASHAFHPIDGYLQSLPYHLFPMLFPLHKVSYLVLFTFVNVWTVMIHDGEYLSNDPVINGAACHTVHHLYFNYNYGQFTTLWDRLGGSYREPDHELFDSNLKKDKAVWEQQIKEVDEMIKNVEGPADDRVYER
What is the function of this protein?
Catalyzes the introduction of a C-5 double bond in the B ring of ergosterol.  May contribute to the regulation of ergosterol biosynthesis.
What are the official names of this protein?
Delta(7)-sterol 5(6)-desaturase, C-5 sterol desaturase, Ergosterol Delta(5,6) desaturase, Sterol-C5-desaturase.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CYC_PACTA
Sequence: MPAPYEKGSAKKGATLFKTRCLQCHTTEAGGAHKVGPNLNGVFGRHSGQAEGYSYTDANKQKGALWEAQTMSDYLENPKKYIPGTKMAFGGLKKAKDRNDLVTYLLSATK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: LEGB_GOSHI
Sequence: MAYTSLLSFSVCLLVLFHGCCAQIDLVTNHHQDPPWGQPQQPQPRHQSQCQLQNLNALQPKHRFRSEAGETEFWDQNEDQFQCAGVAFLRHKIQRKGLLLPSFTSAPMLFYVEQGEGIHGAVFPGCPETYQSQSQQNIQDRPQRDQHQKLRRLKEGDVVALPAGVAHWIFNNGRSQLVLVALVDVGNDANQLDENFRKFFLAGSPQGGVVRGGQSRDRNQRQSRTQRGEREEEESQESGGNNVLSGFRDNLLAQAFGIDTRLARKLQNERDNRGAIVRMEHGFEWPEEGQRRQGREEEGEEEREPKWQRRQESQEEGSEEEEREERGRGRRRSGNGLEETFCSMRLKHRTPASSADVFNPRGGRITTVNSFNLPILQYLQLSAERGVLYNNAIYAPHWNMNAHSIVYITRGNGRIQIVSENGEAIFDEQVERGQVITVPQNHAVVKKAGRRGFEWIAFKTNANAKISQIAGRVSIMRGLPVDVLANSFGISREEAMRLKHNRQEVSVFSPRQGSQQ
What is the function of this protein?
This is a seed storage protein.
What are the official names of this protein?
Legumin B, Beta-globulin B, LEGB-C134.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: RECO_STRM5
Sequence: MLIEDDTGFVLHARAYRETSLLVEVLSAQHGRIGVLARGVSTAKGQVLRAALQPLQWIRFSALQRGELAQLRGAEALDAAPRLVGQAMLAGFYLSELTLRLAPRQDPLPELYLAYGEARARLGVGAGLAWTLRRFERELLTSLGLGFELDSASDGQPIDPAARYELDPQEGAQRLLSERAGERRAAATGSALLALAADEEPDAADLASLRLPMRRVLAHHLGPRGLKSWEMLEQLAPKR
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RIMO_SORC5
Sequence: MSSRKVHFVSLGCPKNRVDSEVMLGVARAAGFAHVDDAAEAEVIVVNTCGFIGEAKKESIDAIFEMAQHKEHGSCKRLVVAGCLSQRHPEELAREMPEVDHFLGSSDMLKLGRVLAGDAERMLVGNPAEWLIQAGDPRTLSTPGGSAYVKIAEGCNRTCSFCVIPDLRGAQRSRPIPDVVREVEQLAAAGVREINLISQDTIAYGRDAAGRSEGGARATLAQLVERVADVPGVRWVRLFYLYPETMTDDLVELLAGHPRVVPYVDMPLQHAADAMLRRMRRGHGGDRLRRVVSTLRERVPDLTFRTAFIVGHPGETDAEFEELCDFVRWAEFERVGVFRYSDEEASRSYELEGKVPARTAASRYRRLMTLQRRISHKKSAAMIGRELEVLVEGTSDEHEYVLMGRHAGQAPEIDGQVYLSGGEVRPGEMCRVRITQASDYDLVGELLDDEESGRGAGLPPAADLGAVTAKRRVALRVLQTDGRERQQN
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD1B_RABIT
Sequence: MLLLPLLLLAGRFPGGDNEDALQGPTSYHVMQISSFTNSTWTENRGSGWLEDLQIHRWDSETGTAIFLKPWSKGNLSDEEITELVELFRVYFFGLVRELRDHVTEFQMK
What is the function of this protein?
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD1b, Leukocyte differentiation-like antigen Ta.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
Protein: RS4_BURO1
Sequence: MARYIGPKAKLSRREGTDLFLKSARRSLADKCKLDSKPGQHGRTSGARTSDYGTQLREKQKVKRIYGVLERQFRRYFAEADRRKGNTGENLLQLLESRLDNVVYRMGFGSTRAEARQLVSHKSITVNGVVANVPSQQVKAGDVVAIREKAKKQARIVEALSLAEQGGMPSWVAVDAKKFEGTFKQMPERAEIAGDINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: XCL1_MOUSE
Sequence: MRLLLLTFLGVCCLTPWVVEGVGTEVLEESSCVNLQTQRLPVQKIKTYIIWEGAMRAVIFVTKRGLKICADPEAKWVKAAIKTVDGRASTRKNMAETVPTGAQRSTSTAITLTG
What is the function of this protein?
Chemotactic activity for lymphocytes but not for monocytes or neutrophils.  In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
What are the official names of this protein?
Lymphotactin, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, Small-inducible cytokine C1.
What is the protein family that this protein belongs to?
Belongs to the intercrine gamma family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARL6_PONAB
Sequence: MGLLDRLSILLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQNILPTIGFSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSSDRLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDAVTSVKVSQLLCLENIKDKPWHICASDAIKGEGLQEGVDWLQDQIQTVKT
What is the function of this protein?
Involved in membrane protein trafficking at the base of the ciliary organelle.  Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia.  Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation.  May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade.  Isoform 2 may be required for proper retinal function and organization (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=Appears in a pattern of punctae flanking the microtubule axoneme that likely correspond to small membrane-associated patches. Localizes to the so- called ciliary gate where vesicles carrying ciliary cargo fuse with the membrane (By similarity).
Protein: DTPB_ASPFN
Sequence: MVKNNAGIVNMFEKRRTQTTTIPIIEIMREKRSEDLETEIVQGLQFDSLQLPQELLWDDAGQILFDDLCNSSTYYLTKKEKEILQKYSTDMAATIPEGSTLIELGCGSLRKTGILLSALEKSHKAVTYYALDVSQDSLENGLAQLHKGLGCLDHVELRGLWGTYEDAIAWLADQHPINVHNGITFLWMGNSMTNMHLAQAQSLLSRMTKTCIGSGIPCQILVSVDSCSAEDIVMGAYDTDSQPLKDFIMNGLKSANRILGKDVFCASDWTFGTVLDRVRHEVQVFYAPTRDVTIHIDSHPCKITKGEKIAVISSGKWPEPYFRSMLEGIGLQVLDLWRDSDQFYCMNPLPLICSFPG
What is the function of this protein?
N-methyltransferase; part of the gene cluster that mediates the biosynthesis of the dimeric diketopiperazine alkaloid ditryptophenaline (PubMed:24677498).  The nonribosomal peptide synthase dtpA accepts L-tryptophan and L-phenylalanine as its substrates and forms the phenylalanyl-tryptophanyl cyclic dipeptide product cyclophenylalanyltryptophenyl (PubMed:24677498).  The N-methyltransferase dtpB is responsible for the N-methylation of cyclophenylalanyltryptophenyl to yield cyclo-N-methylphenylalanyltryptophenyl (PubMed:24677498).  The cytochrome P450 monooxygenase is responsible not only for pyrroloindole ring formation but also for concurrent dimerization of N-methylphenylalanyltryptophanyl diketopiperazine monomers into a homodimeric product (PubMed:24677498).
What are the official names of this protein?
N-methyltransferase dtpB, Ditryptophenaline biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: ISPH_SHIDS
Sequence: MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: YIDC_SHEB9
Sequence: MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAAVTATSKLITVKTDQLDVQINPIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSGLIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYVADNGVTYTKVFVFHRGKFNVDVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAKSNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQEISSQFYVGPKDQKALSAISDTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGLAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDRQKMGQAMMELYKKEKVNPMGGCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKMQPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGLK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURI_STRSY
Sequence: MDNRPIGFLDSGVGGLTVARELMRQLPHEEIVYIGDSARAPYGPRPAEQIREYTWQLVNFLLTKNVKMIVFACNTATAVVWEEVKEKLDIPVLGVILPGASAAIKATQTGKVGVLGTAMTIQSDIYREKIQALSPETQVDSLACPKFAPLVESNSHQSSLAKKVVYETLRPLVGQVDTLVLGCTHYPLLRPIIQNAMGKDVKLIDSGAECARDISVLLNYFQINRSRTEKDIQHRFYTTASPAAFKEIAESWMGIDIHVEHVEL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: RNJ1_STAA8
Sequence: MKQLHPNEVGVYALGGLGEIGKNTYAVEYKDEIVIIDAGIKFPDDNLLGIDYVIPDYTYLVQNQDKIVGLFITHGHEDHIGGVPFLLKQLNIPIYGGPLALGLIRNKLEEHHLLRTAKLNEINEDSVIKSKHFTISFYLTTHSIPETYGVIVDTPEGKVVHTGDFKFDFTPVGKPANIAKMAQLGEEGVLCLLSDSTNSLVPDFTLSEREVGQNVDKIFRNCKGRIIFATFASNIYRVQQAVEAAIKNNRKIVTFGRSMENNIKIGMELGYIKAPPETFIEPNKINTVPKHELLILCTGSQGEPMAALSRIANGTHKQIKIIPEDTVVFSSSPIPGNTKSINRTINSLYKAGADVIHSKISNIHTSGHGSQGDQQLMLRLIKPKYFLPIHGEYRMLKAHGETGVECGVEEDNVFIFDIGDVLALTHDSARKAGRIPSGNVLVDGSGIGDIGNVVIRDRKLLSEEGLVIVVVSIDFNTNKLLSGPDIISRGFVYMRESGQLIYDAQRKIKTDVISKLNQNKDIQWHQIKSSIIETLQPYLFEKTARKPMILPVIMKVNEQKESNNK
What is the function of this protein?
An RNase that has 5'-3' exonuclease and endonuclease activity, with the exonuclease activity probably being most important in vivo.  Involved in maturation of 16S rRNA, rnpB (the RNA component of RNase P) maturation and degradation, and mRNA maturation and/or decay.  This subunit has the exonuclease activity.
What are the official names of this protein?
Ribonuclease J 1, RNase J1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_DESDA
Sequence: MLAPKKVKFRKWQKGRLRGLATRGATVAFGDIGLKAVQHGQLTSQQIEAARIAMMRHIKRGGKVWIRVFPDRPVTAKPLETRQGSGKGAPVGWCAPVKPGRVLYEIKGVSLDLAREALTRAAHKLPVKTVIVVREGI
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: NCAP_CCHFI
Sequence: MENKIEVNNKDEMNRWFEEFKKGNGLVDTFTNSYSFCESVPNLDRFVFQMASATDDAQKDSIYASALVEATKFCAPIYECAWVSSTGIVKKGLEWFEKNAGTIKSWDESYTELKVDVPKIEQLTGYQQAALKWRKDIGFRVNANTAALSNKVLAEYKVPGEIVMSVKEMLSDMIRRRNLILNRGGDENPRGPVSHEHVDWCREFVKGKYIMAFNPPWGDINKSGRSGIALVATGLAKLAETEGKGIFDEAKKTVEALNGYLDKHKDEVDRASADSMITNLLKHIAKAQELYKNSSALRAQSAQIDTAFSSYYWLYKAGVTPETFPTVSQFLFELGKQPRGTKKMKKALLSTPMKWGKKLYELFADDSFQQNRIYMHPAVLTAGRISEMGVCFGTIPVANPDDAAQGSGHTKSILNLRTNTETNNPCAKTIVKLFEVQKTGFNIQDMDIVASEHLLHQSLVGKQSPFQNAYNVKGNATSANII
What is the function of this protein?
Binds dsRNA and ssRNA and probably participates in the packaging of viral genome.  In the dsRNA binding mode, the nucleocapsid protein specifically binds to the vRNA panhandle secondary structure formed at the termini of viral genome.  Does not discriminate between viral and nonviral RNAs through ssRNA binding mode (PubMed:28922369).  Displays dsDNA endonuclease activity that is sequence non-specific (PubMed:22421137).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the nairovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Note=Internal protein of virus particle.
Protein: SEGN_XENTR
Sequence: MDSAFLKLDAAEFLEIWQRFDADDNGYIEGKELDEFFCHLLKKLGANAITAEKVQRVKDRFMSAYDVTADGRLQIQELANMILPEDENFLLLFRRETPLDNSVEFMRIWRKYDEDSSGFISAVELRNFLQDLFLQHKKQITGDKLDEYTDTMMKLFNKNKDGRLDLNDLAKILALQENFLLQFKMDASSQDERKRDFETIFAHYDVSKTGALEGPEVDGFVKDMMELVKPSISGVDLDKFRQILLNHCDVNKDGKIQKSELALCLGLKPHP
What are the official names of this protein?
Secretagogin.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_GEOSE
Sequence: MSKMRVYEYAKKQNVPSKDVIHKLKEMNIEVNNHMAMLEADVVEKLDHQYRPKAEKKTETKNEKKAEKKTDKPKRPMPAKTADFSDEEIFDDVKEAAKPAKKKGAAKGKETKRTEAQQQEKKAFQAAKKKGKGPAKGKKQAAPAAKQVPQPAKKEKELPKKITFEGSLTVAELAKKLGREPSEIIKKLFMLGVMATINQDLDKDAIELICSDYGVEVEEKVTIDETNFEAIEIADAPEDLVERPPVVTIMGHVDHGKTTLLDAIRHSKVTEQEAGGITQHIGAYQVTVNDKKITFLDTPGHEAFTTMRARGRQVTDIVILVVAADDGVMPQTVEAINHAKAANVPIIVAINKMDKPEANPDRVMQELMEYNLVPEEWGGDTIFCKLSAKTKEGLDHLLEMILLVSEMEELKANPNRRAVGTVIEAKLDKGRGPVATLLVQAGTLKVGDPIVVGTTYGRVRAMVNDSGRRVKEAGPSMPVEITGLHDVPQAGDRFMVFEDEKKARQIGEARAQRQLQEQRSVKTRVSLDDLFEQIKQGEMKELNLIVKADVQGSVEALVAALQKIDVEGVRVKIIHAAVGAITESDISLATASNAIVIGFNVRPDANAKRAAESEKVDIRLHRIIYNVIEEIEAAMKGMLDPEYEEKVIGQAEVRQTFKVSKVGTIAGCYVTDGKITRDSKVRLIRQGIVVYEGEIDSLKRYKDDVREVAQGYECGLTIKNFNDIKEGDVIEAYVMQEVARA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_BREBN
Sequence: MDYSKTLALPKTEFPMRGNLPSREPQMQAVWEEQNIYQQVLDRTKDRPSFVLHDGPPYANGDIHIGHALNKILKDFIVRYKSMAGFYAPYIPGWDTHGLPIEQAIINAQGLDRRSIEVNDFRQRCEEYAWSYIDKQRDQFKRLGVRGDWENPYVTLLPEYEANQIRVFGEMAKKGYIYKGLRCVYWSPSSETALADAEIEYKDKRSPSIYVSFQVADGKGKLDIETGVVIWTTTPWTLPANLAISLHPELEYNVVKVDGRKFLVANGLIEAASKEIGWEGVEILATFKGQELEGVETQHPFYDRKSPLILGEHVTLDAGTGCVHTAPGHGEDDFNVGQKYNLGVLCPVDHEGKMTNEAPGFEGLFYEDANKVITEKLKENGALLKLSFFTHSYPHDWRTKKPVIYRATEQWFASIDGFRTQMLEAIKNVKWIPHWGETRLANMIADRGDWCISRQRVWGVPIPIFYCKACNEPIINDTTINHVADLFRKEGSKVWFSREANELVPEGLSCTKCDCNDFRKETDIMDVWFDSGSSHQAVLRERGIAWPADMYLEGSDQYRGWFNSSLSTGVAVYGTAPYKSVLSHGFALDGEGRKMSKSLGNVIVPQQVIDKMGADILRLWVASVDYQADVRISDAILNQIAEVYRKIRNTFRFLLGNLDGFNPATDRVAYEELGELDRYVLAKAAKVAKRTRKAYDEYQFHTVFHAVHNFCVIDLSAFYLDICKDRLYVEAPDSLKRRAAQTVMYDCLLSLVKLVAPLLPHTADEVWAFIPGVEEKSVQLTDMPEGDEQHLSFAAEAESKWDAFLAIRDEVLKAMEEARRNKVFGNSVDAKLALYPQTEEVAKTLAAMDDLADLFIVAHVDVHSGSAPAEAVQLEGIAAVVSAADGGKCERCRVVKPDVGTRESHASLCVRCADVVEQHYAHVTE
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACOT6_MOUSE
Sequence: MAATLSVEPAGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGMLFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQIPFVVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGKGQFPGIIDLYGSIGGLCEHRASLLAGHGFAVLALAYFQFEDLPENLSDVRLEYFEEALALMLRHPQVKGPNIGLIGVSKGADLCLSMAAFLKDNITATVLINACVANTLVPLYYKDLFVPELGCDQTKNKSGLMDLRDMWNNPLEEPNHQSLIPLEKAQGPFLFLVGMDDHNWKSDVYARIACERLQAHGKDRPQIIYYPETGHCIEPPYFPPPIATVHFVLGEAVFNGGKPRAQSRAQLDAWQRIQTFFQKYLNGEKPARHSKL
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels.  Catalyzes the hydrolysis of phytanoyl-CoA and pristanoyl-CoA, two methyl-branched fatty acids derived from phytol, that enter the body via the diet.
What are the official names of this protein?
Acyl-coenzyme A thioesterase 6, Acyl-CoA thioesterase 6.
What is the protein family that this protein belongs to?
Belongs to the C/M/P thioester hydrolase family.
What are the subcellular locations of this protein?
Peroxisome.