PharMolix/UniProtQA huggingface dataset:
Protein: CLUS_COTJA
Sequence: MELPLLALLSLGLVCQGGQGLVPPNELKQLSAAGSKYIDAEVENAINGVKQMKTLMDKTSKEHQAMLHTLEETKKKKEEAVKLALEKEKQLAEKQEVCNETMLSLWEECKPCLKHTCMRVYSKMCHSGSGLVGRQLEEFLNRSSPFSIWVNGERIDDLLDREQRQERRFEDLEERFGLMEDGVEDIFQDSTQLYGPAFPFFRTPPFGGFREAFVPPVQRVHLVPRRRLSRELHPFFQHPMHGFHRLFQPLFEMTQHMLDGGHGAWEHPLGGFATESRNFSTDRMVCREIRRNSAGCLRMRDECEKCREILAVDCSQTDPVQSQLREQFEDALRLAERFTRRYDDLLSAFQAEMLNTSSLLDQLNRQFGWVSRLGNLTQGNDGFLQVTTVFSKTPNLEDPSAPADTQVTVQLFDSEPLSLTVPGDISWDDPRFMEIVAEQALQHYKQNNTIE
What is the function of this protein?
Functions as extracellular chaperone that prevents aggregation of nonnative proteins.  Prevents stress-induced aggregation of blood plasma proteins.  Does not require ATP.  Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70.  Does not refold proteins by itself.  Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation.  When secreted, protects cells against apoptosis and against cytolysis by complement.  Intracellular forms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins.  Modulates NF-kappa-B transcriptional activity.  Promotes apoptosis when in the nucleus.  Inhibits apoptosis when associated with the mitochondrial membrane by interference with BAX-dependent release of cytochrome c into the cytoplasm.  Plays a role in the regulation of cell proliferation (By similarity).
What are the official names of this protein?
Clusterin, 51.5 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the clusterin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Nucleus. Cytoplasm. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Endoplasmic reticulum. Note=Present in chromaffin granules. Can retrotranslocate from the secretory compartments to the cytosol upon cellular stress. Detected in perinuclear foci that may be aggresomes containing misfolded, ubiquitinated proteins. Detected at the mitochondrion membrane upon induction of apoptosis (By similarity).
Protein: LIPA_BAUCH
Sequence: MVKIEKKLHKPLWLKIKLPSSDYKIKVIKKTMNKSSLYTICEEACCPNLAECFNNGTATFMILGNICTRRCPFCNVAHGRPLIPDIHEPEKLAETITNMGLRYVVITSVNRDDLYDGGAQHFVDCIRAIRAKNSATRIEVLVPDFRGHMKTALEILNTSPPDVFNHNIENVPRLYRHIRPGADYHRSLKLLKKFKEYNPSLPTKSGLMMGLGETREEIIEVMRDLRQHNVTMLTLGQYLQPSSNHLPVQRYITPQEFNEMKLESLAMGFTYAACGPFVRSSYHADLQNKGIEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADB_SACS2
Sequence: MIYIFGSGLAGLSAAISLHKSGYKVTIISKKINGGSSYWAKGGIAAAVGNDDSPELHKIDTLEVGDGLCDSKTVDYVTREIRYVVSTVEKWGFKFDDDLRLEGGHSKRRILHKTDDTGREITNFLLNLAKKKGINLIEDKLLALKVKDGKVAGFITEKGGSFDAEKVVLATGGYGYLFKFTSNPSTNIGDGIAIAFKAGALVSDTEFVQFHPTVTTFDGQAYLLTETLRGEGAILVNERNERFVFKYDSRGELAPRDVLSRAIYDQYKKGHTVYIDLSPIEDFDRKFPILSNYVKRYGKRLQVFPGVHYTIGGIRVNTRGESNIKGLYAIGEVTDTGLHGANRLASNSLAEDLVYGVNLVRYIDNWEGLSIDDVKEVIEVRLRNSSNRLSLEEIREYNWNYLGIVRNGEGLDKLVKIYESNDTFNDNASLVSLLSAKGALLRTESRGAHYREDYPNKSWEDGKRIYFMVSRN
What is the function of this protein?
Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
What are the official names of this protein?
L-aspartate oxidase, LASPO, Quinolinate synthase B.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUSPR_DICDI
Sequence: MVLINRVNIQPEELPLLYHVNSMDVYNLLQDIGSSKIIIDLRTKEQYEKNHIRTSVNIPPPPSTTPLYENGEIKEFNLSKYIGSNVTAKHWNLIFQKLIVYSDKPFLYNIDELEKTISTTTITTTATTTTTTTTTSNSIGSDQDIIKSLKVSDWDKVVLRHFLLKKKKTKVIIYQGGFDQFQKDYSFMCNPSSSPSSSSGGGGGSQLYPSEIIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLTLEWEKQEKLKKQQQQTLNINNNNTGIPLSKKLQLDVSDPLSNSSPSSPLISSTLPIPETPPAIILKNEVASPCPIKTTTSSTTINNKGQQQDKAQEEKDSIFSYADKQEKMTHPTLHSPIELPQSSL
What is the function of this protein?
Has a dual specificity toward Ser/Thr and Tyr-containing proteins.
What are the official names of this protein?
Probable rhodanese domain-containing dual specificity protein phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Protein: ARGB_ECOL5
Sequence: MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRQLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTNEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_NOCFA
Sequence: MARMSEPSPYVEFDRKQWRTLRKSTPLVLTEEELIGLRGLGEQIDLEEVAEVYLPLARLIHLQVAARQRLFAATATFLGEKHPDRQVPFVIGVAGSVAVGKSTTARVLQALLARWEHHPRVDLVTTDGFLYPTAELTRRGIMHRKGFPESYDRRKLLRFVTEVKSGAEEVCAPVYSHISYDIVPGKLHCVRQPDILIVEGLNVLQTGPRLMVSDLFDFSIYVDARIEDIEKWYVQRFLALRKTAFADPDAHFHHYASLTDEQATLAAQEIWNSTNRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSOP3_ARATH
Sequence: MAEEAKSKGNAAFSSGDYATAITHFTEAINLSPTNHILYSNRSASYASLHRYEEALSDAKKTIELKPDWSKGYSRLGAAFIGLSKFDEAVDSYKKGLEIDPSNEMLKSGLADASRSRVSSKSNPFVDAFQGKEMWEKLTADPGTRVYLEQDDFVKTMKEIQRNPNNLNLYMKDKRVMKALGVLLNVKFGGSSGEDTEMKEADERKEPEPEMEPMELTEEERQKKERKEKALKEKGEGNVAYKKKDFGRAVEHYTKAMELDDEDISYLTNRAAVYLEMGKYEECIEDCDKAVERGRELRSDFKMIARALTRKGSALVKMARCSKDFEPAIETFQKALTEHRNPDTLKKLNDAEKVKKELEQQEYFDPTIAEEEREKGNGFFKEQKYPEAVKHYSEAIKRNPNDVRAYSNRAACYTKLGALPEGLKDAEKCIELDPSFTKGYSRKGAIQFFMKEYDKAMETYQEGLKHDPKNQEFLDGVRRCVEQINKASRGDLTPEELKERQAKAMQDPEVQNILSDPVMRQVLVDFQENPKAAQEHMKNPMVMNKIQKLVSAGIVQVR
What is the function of this protein?
Mediates the association of the molecular chaperones HSP70 and HSP90.  Mediates nuclear encoded chloroplast preproteins binding to HSP90 prior to chloroplastic sorting (By similarity).  Involved in acclimation to heat.
What are the official names of this protein?
Hsp70-Hsp90 organizing protein 3, AtHop3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PDXK_STAES
Sequence: MALKKVLTIAGSDTSAGAGMQADLKTFQELDVYGMVALTSIVTMDKETWSHDVTPIDMNVFEKQLETAISIGPDAIKTGMLGTQDIIKRAGDVFVESGADYFVVDPVMVCKGEDEVLNPGNTEAMIQYLLPKATVVTPNLFEAGQLSGLGKLTSIEDMKKAAQVIYDKGTPHVIIKGGKALDQDKSYDLYYDGQQFYQLTTDMFQQSYNHGAGCTFAAATTAYLANGKSPKEAIIAAKAFVASAIKNGWKMNDFVGPVDHGAYNRIEQINVEVTEV
What is the function of this protein?
Phosphorylates B6 vitamers; functions in a salvage pathway.  Uses pyridoxal, pyridoxine, and pyridoxamine as substrates (By similarity).
What are the official names of this protein?
Putative pyridoxine kinase, PN/PL/PM kinase, Pyridoxal kinase, Pyridoxamine kinase, Vitamin B6 kinase.
What is the protein family that this protein belongs to?
Belongs to the ThiD family.
Protein: AROC_NOSP7
Sequence: MGNIFGHLFRISTFGESHGGGVGVVIDGCPPQLEISAEEIQVELDRRRPGQSKITTPRKEADTCEIISGVFEGKTLGTPITILVRNQDTRPQDYDEMAQKYRPSHADATYDAKYGIRNWQGGGRSSARETIGRVAAGAIAKKILRQVANVEIIAYVKRIKDLEGVVDPNTVTLEQVESNIVRCPDAECGDRMIELIEQIGRQGDSIGGVVECVARNVPKGLGEPVFDKLEADIAKGVMSLPASKGFEIGSGFAGTLLTGIEHNDEFYIDQNDEIRTVTNRSGGIQGGISNGENIILRVAFKPTATIRKEQKTVTREGEETLLAAKGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHGQCKVL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HIS8_ALIB4
Sequence: MRFNEVLKDVSTYEAGKPIELVVREYGIDSKDVIKLASNENPYGTSPKVIAKIQELAKNMCLYPDDSMYELKDALAKKYNLESSNIIIGSGSDQILEFCIHAKCKKDSKILMAKTTFAMYEIYGKHVGAEIIKTNSEQHNLEEFSELYKKHGADIIFLCIPNNPLGECLDKNDVYEFLKTIDKNTLVVVDGAYQEYAAFKDEKKRICPKDLIDTFPNAIYLGTFSKAYSLGGMRVGYGFAQNEIIQNLYKIRAPFNITTLSLAAAIEALKDEEFVNDCISKNFEEMKRYEEYVTKKGFEYIPSYTNFITIKFGDKYVSKEVAQKLLERGMIVRDLTSYKQNAIRVTIGKPEQNTKLFQLLDEVLQNL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: DAPB_SALA4
Sequence: MHEAQIRVAIAGAGGRMGRQLIQAAMAMEGVQLGAALEREGSSLLGSDAGELAGAGKSGVIVQSSLEAVKDDFDVFIDFTRPEGTLTHLAFCRQHGKGMVIGTTGFDDAGKQAIREASQEIAIVFAANFSVGVNVMLKLLEKAAKVMGDYSDIEIIEAHHRHKVDAPSGTALAMGEAIAGALDKNLKDCAVYSREGYTGERVPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKASSRMTFANGALRSALWLKTKKNGLFDMRDVLGLDVL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAF_SALPK
Sequence: MQKLKQQVFDANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSGVAYETMKVDDMVVVDMDGKVVEGRYRPSSDTATHLALYQRYPSLGGVVHTHSTHATAWAQAGMAIPALGTTHADYFFGDIPCTRALSEEEVQGEYELNTGKVIIETLGEVEPLHTPGIVVYQHGPFAWGKDAHDAVHNAVVMEEVARMAWIARGINPGLNPIDDYLMNKHFMRKHGPNAYYGQK
What is the function of this protein?
Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 4-epimerase UlaF, L-ascorbate utilization protein F, Phosphoribulose isomerase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: PP203_ARATH
Sequence: MRFTFLRSTRIFLANHQNHLSSLQNIRTIPSSSSSPVAISSVSKLSASLDHLSDVKQEHGFMVKQGIYNSLFLQNKLLQAYTKIREFDDADKLFDEMPLRNIVTWNILIHGVIQRDGDTNHRAHLGFCYLSRILFTDVSLDHVSFMGLIRLCTDSTNMKAGIQLHCLMVKQGLESSCFPSTSLVHFYGKCGLIVEARRVFEAVLDRDLVLWNALVSSYVLNGMIDEAFGLLKLMGSDKNRFRGDYFTFSSLLSACRIEQGKQIHAILFKVSYQFDIPVATALLNMYAKSNHLSDARECFESMVVRNVVSWNAMIVGFAQNGEGREAMRLFGQMLLENLQPDELTFASVLSSCAKFSAIWEIKQVQAMVTKKGSADFLSVANSLISSYSRNGNLSEALLCFHSIREPDLVSWTSVIGALASHGFAEESLQMFESMLQKLQPDKITFLEVLSACSHGGLVQEGLRCFKRMTEFYKIEAEDEHYTCLIDLLGRAGFIDEASDVLNSMPTEPSTHALAAFTGGCNIHEKRESMKWGAKKLLEIEPTKPVNYSILSNAYVSEGHWNQAALLRKRERRNCYNPKTPGCSWLGDYSI
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g46050, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y2306_STAES
Sequence: MRGGGNMQQMMKQMQKMQKKMAQEQEKLKEERVAGTAGGGMVTVTVTGHKEVVDVEIKEEAVDPEDIEMLQDLVLAATNEAMNKADELTQQRLGKHTQGLNIPGM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SE_2306.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: XERC_VIBC1
Sequence: MTTTPNTPLPNSLQKPLERFYEFLRSEKGLSLHTQRNYKQQLETMAHHLAEMGLKDWSQVDAGWVRQLAGKGMREGMKASSLATRLSSLRSFFDFLILRGEMLANPAKGVSAPRKKRPLPKNLDVDEVNQLLEVNEDDPLAVRDRAMMELMYGAGLRLAELVSVDVRDVQLRSGELRVIGKGDKERKVPFSGMATEWVGKWLRVRGDLAAPGEPALFVSKLGTRISHRSVQKRMAEWGQKQSVASHISPHKLRHSFATHMLESSNNLRAVQELLGHENISTTQIYTHLDFQHLAQAYDQAHPRARKRNDDKSD
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO_CITK8
Sequence: MKKVTAMLFTMAVGLNAVSMAAKAKATEEQETDVLLIGGGIMSATLGTYLQELEPEWSMTMVERLDGVAQESSNGWNNAGTGHSALMELNYTPKKADGSVSIEKAVDINEAFQVSRQFWAHQVQSGVLHEPHSFINTVPHMSFVWGDDNVNFLRARYTALQQSTLFRGMRYSEDHAQIKEWAPLVMEGRDPKQKVAATRTEIGTDVNYGEITRQLVASLQKKPNFALQLNTEVRGFKRNADNSWTVTVADLKNGEAEHAIKAKFVFIGAGGAALKLLQETGIPEAKDYAGFPVGGQFLVSENPDVVNNHLAKVYGQASVGAPPMSVPHIDTRILDGKRVVLFGPFATFSTKFLKNGSLWDLLSSTTTSNFMPMVNVGMDNFDLVKYLISQVMLSDDERFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDEDKGGVLRLGTEVVSDKDGTIAALLGASPGASTAAPIMLHLMEKVFKEKVASPEWQAKLKTIVPSYGTKLNGNIEATEQELQYTSDVLGLKYDKPQVVDEAPKPQLKPQVQPQPAHKAVADIAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: RSMA_MARMM
Sequence: MSLDQLPPLRDVIASHDLGAKKSFGQHFLLDLNLTAKIARLAGDMSRDQAIEVGPGPGGLTRAILAEGAASLLAVEMDSRFLGALDEINVASGGRLTVEQGDALEVDETALLTGPGDKVILSNLPYNVGTQLLIKWLQAEPIWWRRAVLMFQREVADRVVAQPGDKAYGRLAVISQSRCQAHLALKIPARAFTPPPKVESAVVVLDPLPEAQQFKDVVALERITASAFGQRRKTLRRSLAQAAGQGGTSADALLEEAGLNAGDRAEVIDITGFQSLARAWRAAYDAGRA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y214_PYRHO
Sequence: MLKEILSSALLMLIMIDPSDKILLVSLLREDFHIEDVKSLIIRANLIGFILLLLFAVAGKIILQDIFHIELDALRVAGGFVLFKIGLEALEGGGMVTIKREKNILALAAVPVATPLIAGPAAITAAITLTAEHGIIVSIVGTLIAIAITAALMMIALYLMRGISKTALSVTIRIIGLFIMAIGAQMMITGAGGIVLNLIKGA
What are the official names of this protein?
UPF0056 membrane protein PH0214.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRAY_CORA7
Sequence: MTQIIIAGAVSFLVAIFTTPVLIRYFSDTGRGQEIREDGPKSHLRKRGTPTMGGLAILAGILVAYVVAGLYGLLTGHEAFTASGLLVLGLTLGLGAVGFADDFIKLFRHRNLGLNKTAKLISQLVLALLFGFLVLRFPNDAGLTPGSTKLSFIRDLKTFDLAVGGTVIGTIVFLIFMYILIAAWSNAVNLTDGLDGLAAGVTAIVMGSYSLMTFWQFRYSCATNFAAGCYQVRDPLDLAVLAAAGLGGCLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVTSRTELLMIIIGALFVIETVSVVIQIVVFHSTGKRFFRMAPIHHHFENGGWAETAVVVRFWLLAAMAAMAGVAIFYGDWLTASGIGVGA
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS14Z_MESHJ
Sequence: MAKTSWKVKANRAPKFKVRAYTRCQLCGRSHSVLRKFRICRICFRVLAHQGRIPGIKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RSMJ_HAHCH
Sequence: MISYDDQVLVSYSNQRWEEAEAFSSQFGLRLVALEALPAKSDRAVYLLNFSDTRVELVNWREQAPGPVFVDFVEGALAYRREHGGGRGEMVAKSVGLKGEVKCLNVLDATAGLGRDAYVLAALGCHVVMYERNPLVHALLADGLRRALECADAASVVSRMTLHLGEAFNTFPDGIDVVYLDPMFPERRKSSAVKKEMQAFKDIVGADPDADELLAAALRQEVKRIVVKRPKGAPCLLGREPSFTVTGKSGRFDVYALRKLTGG
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_STRZJ
Sequence: MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLVIALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFIIDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAVALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLVQLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKGGGFQKLFYTHPPISERIERLKHM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPB_FRATT
Sequence: MSTGKIIQVIGAVIDVEFARDNTPKVYDALNVVEAGLVLEVQQQIGDGVVRTIAMGSSDGLRRGMEVKNTNAPISVPVGHGTLGRIMNVLGEPIDEAGPIEYTEKRSIHQAPPAYDELALSTEILETGIKVVDLICPFAKGGKVGLFGGAGVGKTVTMMELINNIAKEHSGYSVFAGVGERTREGNDFYYEMKDSNVLDKVSLVYGQMNEPPGNRLRVALSGLTIAEGFRDEKRDVLMFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAAEMGALQERITSTKTGSITSVQAVYVPADDLTDPSPATTFSHLDATIVLSRQIAELGIYPAVDPLDSTSRQLDPLVVGQDHYETARAVQKVLQRYKELKDIIAILGMDELSDEDKKIVDRARKIQRFLSQPFHVAEVFTGNPGKFVSLKDTVASFKAIVNGEYDHLPEQAFYMVGSIQEAIEKAKTL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GPMA_BURMA
Sequence: MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRAIRTLWHVQDQMDLMYVPVVHSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIAAHGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPIRHYYLGDQEAIAKAQAAVAQQGKSAA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: KSL6_ORYSJ
Sequence: MMLPMSSACSGGQFPGASPHGIIPKQFSRAPRIRVSIRGAAGVEKSLGLGRNAGSQQGMHKNELHDKIRKQLRDVQLQPSSYDTAWVAMVPVQGSHQTPRFPQSIEWILQNQYDDGSWGTNLPGLVVNKDILLCTLACVVALKRWNTGRDHISRGLNFIGRNFSVAMDEQTVAPVGFNITFSGLLSLATRTGLELPVMQTDIDGIIHIRKIELERDAYGTASSRRAFMAYVSEGLGNLQDWNQVMAYQRKNGSIFNSPSATAATIIHGHNYSGLAYLDFVTSKFGGPVPVMYPQNAYSQLCMVDTLERMGISESFACEISDILDMTYRLWMHNEEELMLDMRTCAMAFRLLRMHGYDITSDGMAQFVEQSSFDDSIHGYLNDTKALLELYKSSQLRCLEDDLILEEIGSWSARVLLEKISSKMIHISELPEVEYALKCPVYAILERLEQKRNIEQFKTKEQLKIEGFKLLKSGYRGVIPNDEILALAVDEFHSSQSVYQQELQDLNSWVAHTRLDELKFARLMPSITYFSAAAVLLPSESARIAWTQNCILTTTVDDFFDGEGSKEEMENLVKLIEKWDDHGEIGFSSECVEILFYAVYNTSKQIAEKAMPLQKRNAVDHIAESWWFTVRGMLTEAEWRMDKYVPTTVEEYMSAAVDSFAVGPIITSAALFVGPELSEEVFRSEEYIHLMNLANTIGRLLNDMQTYEKEIKMGKVNSVMLHALSHSGGGRGSPEASMEEAKREMRRVLQGCRFELLRLVTRDAGVVPPPCRKLFWLMSKVLHFVYMEKDRYFTAEGMMASANAVILDPLQVTLPPSDSGTL
What is the function of this protein?
Involved in the biosynthesis of ent-kaurene diterpenoids natural products (PubMed:17456599, PubMed:16861806).  Catalyzes the conversion of ent-copalyl diphosphate to the phytoalexin precursor ent-isokaur-15-ene (PubMed:17456599, PubMed:16861806).
What are the official names of this protein?
Ent-isokaur-15-ene synthase, Ent-kaurene synthase-like 5, OsKS5, Ent-kaurene synthase-like 6, OsKS6, OsKSL6, Iso-kaurene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: LCAT_PAPAN
Sequence: MGPPGSPWQWVPLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYHKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKLKEEQRITTTSPWMFPSRLAWPEDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDPVDVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLRGIQHLNMVFSNQTLEHINAILLGAYRQGPPASLTASPEPPPPE
What is the function of this protein?
Central enzyme in the extracellular metabolism of plasma lipoproteins.  Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs).  The cholesterol ester is then transported back to the liver.  Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines.  Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels.  Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins.  Required for remodeling high-density lipoprotein particles into their spherical forms (By similarity).
What are the official names of this protein?
Phosphatidylcholine-sterol acyltransferase, Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into blood plasma. Produced in astrocytes and secreted into cerebral spinal fluid (CSF) (By similarity).