PharMolix/UniProtQA huggingface dataset:
Protein: MURC_CAMC5
Sequence: MKKVHFIGIGGIGISAIARFLFEKGHKISGSDIKESKTTQELKEQGMDVITPHCKEAIKDQDFVVYSAAIKDDNVELVEARKKGIKCFSRKEILPYVLEDKRVFAVAGAHGKSTTSAMLSSLIEGSVIIGAISKQFGSNMRYAQSDNVVFEADESDSSFLNSNPYLAVVTNAEPEHMEHYDYDLAKFYAAYKGFLERAKVRVINAEDEFLSTLKLDAIRLFPSSDITELAMVVRDYQPYTSFNLKNLGKFEVFGMGQHIAIDASLAILAALHETPLKDIRENLLNFKGIKKRFDILSADKNFILIDDYAHHPTEIRATLNSVFEYAKLLGVSNVTAIFQPHRYTRLSTNLEGFKECFKGVDELVILPVYAAGEKPIEVDMKGAFSEYSPIFTDKVERVGEAIEFTDEFGVKNRLSDGIVVGFGAGDISVQLRGGY
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_BORPD
Sequence: MATLQVDVVSAEEAIFAGEAKFVTLPGEAGELGILPGHTPLISRIRPGTVKIVRADGGEENIFVAGGILEVQPGMVTVLADTAIRAADLDEARAVAAREKAEEALRNAKDKADIAVVEAELAMLAAQAVAARKLRQTRNTH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: INO80_CRYNB
Sequence: MGAMDDRRYSYPPPRTSYVQPSTHPSPTASDYRYRSPVLPQHPPTHHSPSSYSASLYGQPKEDPAIAYARMREEMRTAEEARREAEALEYRRKRDMEFAARRPGSELMDDPRRIPHSSFPRSQMYGPSADQSRVMPSRNGKDYISEPPSPSELYPTDEDTERLPIDRYRRDIDVPPLPRQLPPPPSEIGRMADRARSPSAPIAPPLLKVVRKRTKVIRPNDFLVGNEDVWEDGLIRYQSKREDEVRAIAQWAASCQVRNGVGEPSLPQTQDESIKVRKINGDIATPTNKKKRKSRKLNLDDELLGLASSPPGSPNAAAEAEKSESKHHIYGMNGPIDPANPPSPSTIVYPSGLTRAEVIAKCEAGDVEGLTEDDVKAVQDEMWMREKAAQAAENGGVLPTNKDGTVRRKPGPAKGWRKIRGIDKKKETTPGKAQSTTAGSVAGSVADEEAEADIAALLDDSIAKKGKKVKRRKLEEPGAESPRFADAEDEYNEHRPSDSVLLDEIEDEHSRAGSVGESNALDTLPAASAPPKKKNSKTKEPGVGKGRWTRPTKPEKELVKKAEALASRTSKASLAGPSDDTFGVGPGPAEEVQEEIKHEYAPNTHDPRGVSENEAKIRHELVEDLQKQAWSNIVRDVPRIYRVFQGYDQSMKQIAQRRAQACVRNAFGQRNQKTMQRQSGKVNKEGAAKAKRIVKELAAFWRKNEKDEVIARKKAEREALERAKAEEEARETKRQSRKLNFLLTQTELYSHFIGKKIKTKEAEAAEGMDVEEEEKRGMEEIAIGEDGEPLPDLDYDEDDEENLRKHAARGAQAAIQAARDKARAFDDSIVGRGAPLPGDDTMDGDELNFQNPSLGENSVTITQPKMLMAQLKEYQLKGLTWLGNLYEQGINGILADEMGLGKTIQSISLLAYLAEHHNLWGPFLVIAPASTLHNWQQELARFVPRLKALPYWGSPKDRETLRKIWSRKNQTFSEDSPFHILITSYQLAVQDEKYLQGMKWQYMILDEAQAIKSSSSARWKSLLSLHCRNRLLLTGTPIQNSMHELWALLHFIMPQLFDSHEEFAEWFSKDIESSSGGVTGNLKPEQLKRLHMILKPFMLRRVKKHVQKELGDKIEIDLLVDLSQRQREIYKALRQRVSITDLLATAENNTDNGNPKNMRSLVNLVMQFRKVCNHPDLFERADVVSPFVFGEFSQSGNLAREGDGMYLPDSARNAIEVQIPRILWTDGGKLDIPGEQSLAGSDTKILQNLLNIWTPEWINERTKCADAEFGFVKLVGSSPGETSRSAKSPVLVQLLEGAEKERRWTEEGRFVDDSEFAASVKKGFRVPSVIPVLTQPGQVSLREISRRVWDESYLSRDDARCIGDYAIAPIVKPIASNRSFLNAQDRILNQPLAHSTLYGLAPSELHDPLAAEQFSRIAPSVPLTGLIPSSASSQTPVSPLHIPPTKRLIVDSAKLARLDSLLRELKAGGHRVLLYFQMTKMMDLIEEYLIFRQYKYLRLDGSSPIAERRDMVTSWQTNPDIFVFCLSTRAGGLGINLTAADTVIFYDHDWNPSSDAQAMDRAHRVGQTKQVTVYRLVARGTIEERILQMARGKKDIQDVVVGTKSVSDVAKPSEIVSLFMDDEELAESVAKRKQAEAHGYIAPTIIPNGRRSQFGDGLVLDDGEGDDGFFNAAAAARANAEEEEGLGAEEESKGKGKAKAAAAVTFPVPGEKRSHKKGMGKKAQAAAAAAALERVIAGNEEPLAASKPPAKKKVKIALGPDGLPL
What is the function of this protein?
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
What are the official names of this protein?
Chromatin-remodeling ATPase INO80.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SET6_YEAST
Sequence: MTIDGDVHEISPFFQVRQTKWGGRACFSNGNIPKGTTVLQVSNFTGTSISYEFRKEVCHNCFAYANAKTMKYKLNYDYLRDLVCNAHYQINPKKFLGAGLWFCSEHCRTSYLQIPNIIELIECYEILLHHFPSMLKRYNYTSEQEEKLNSILISENVIQSSWDEIESKWIPRINNMKSAKRINQLPPTCEDEYCCIRFVCESLFNLKYMDPQCITYRAFNMLQSNELSKISKFPVLLHFQKLVFQTLYILLPSHLHRMLSIPLLRHILGTEYGNAFGLWQEGEASDSREYFGYWVFPEASYFNHSCNPNITKYRKGNSMLFTMNRDIKKDEQICIDYSGVLDLPTVKRRAFLADSWFFDCACERCKSELQSVH
What is the function of this protein?
Involved in resistance to compounds that target ergosterol biosynthesis, including fenpropimorph, dyclonine, and alverine citrate.  Since a deletion in the absence of these compounds does not have an effect on growth, is more likely to be involved in compound availability.
What are the official names of this protein?
Potential protein lysine methyltransferase SET6, SET domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
Protein: SYT_EHRCJ
Sequence: MINIYFNNNLCKQFHRGIKGYDVVADLFPELKNKAIAVKVNGESYDLSREITENCTFEVITTNSEEGLEIIRHDTAHIMAQAVKEIFPDTQITIGPTIKDGFYYDFATEHNFSSNDLEIIEKKMIEIINKNESFIREVWTREEAIKFFSSIGEDYKVKIISKIPNNENITVYKQGNFIDLCRGPHAPSTKTSKSFKLTKVSGSYWQGNSSNEKLQRIYGTAWRNEEELKSYLNNLIEIEKRDHRKIGKELELFHIQNEACGQVFWHKKGWTIYRTIENYIRKKLETNGYIEVKTPMLLNKELWEKSGHWDKFRENMFLSEAEDKVLAIKPMNCPCHIQIFNSKIRSYRDLPIRMAEFGICHRYEASGALHGLMRVRGFTQDDAHIFCTESQVISEALKFCNLLMEVYKDFGFTNILVKFSDRPENRAGSDETWDRAESALKKSVEAANLNYVLNPGDGAFYGPKLEFVLKDAIGREWQCGTLQMDFVLPERLGAYYVGSDGKKHHPIMLHRAILGTFERFIGILIEHHSGKFPIWLAPTQLSILTISEESIEYANSLKTKAEEHNIRVELDATNEKINYKIRNHIHKKIPVFWIVGKKEVNENSVSIRYLESNTQQVMPIDKALKTLLTCVSI
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOL6_DROPE
Sequence: MGKIKKIQRKGPPATKRPPKAARTESTDSALGLDAHSDLEKPATSSDDGFEEPTPKPKPSKKTTTLPEPVSIIAQKKNKFRTDDAKNVKPPTLEEMKELRDTRNLFHSNLFKLQVKEMLEELQLKTKYTEYIDNWMESFTVFTQRLKDGLVEKSQLEVPLNVDKKISGFIFSKPTKEPQLIGAASTGTLLGPKIVVDVALEMPKDCLHKDDYLNLIYDQKRALYLTYVTNQMRSDPAYSQDKFAFNYHGNNPLKPVLELTPAAKHVSKHLQLRLFITAPQSTFKPGRFVPWNNNIRPTYYNDEWDEEEALPSTQHYNASVLFDLTLAQNQALLDKAFKGRRNFQDGLLLLKVWLRQRELDRGFTGFGSHILASFIVYLNQQRILHQSSSSYQVARTVWNQLANTDWTNGITLAPASGQTEQLSTIAGYYDVCFMDVSGQLNLCANVPLGVYQRVRAEAKLAVDLLNDMKLNSFPYIFMQKCPLYTRVDNILKITNYSSIQQMLVLHSKPQMKYDFASYGYPQLLQILTELLQKGLKQRVQAILPIETVSSAWPVESKAPIIGQAIQLGLILDPEHAYEVLDKGPSSNDDPEGSAEFRKFWGEKSNLRRFQDGSITEAVVWGTTKDAPSKKRLIVRQIVMHLLEHHLQLDSKDIQYIAAELDLVYQLSPWFKVSKVKTKLELQQDTDAEALSPNVIRCYDDLARQLHALDDLPLEIVSISSISPVSRYCEPMPVLPQARMMADHIHASHIQRVIIQLGQSGKWPNELSALRALKTAFLIEIGEKLKAQCRLNWSITSEGLLVLKRGFCFLLELAHNKELALLKQEVTERGVTKYVDNPESRALEQRHYILPKVSGALHSLHQSHSAYGPTVLIAKRWLATQLLDDGIWPPMATELLVAHLYQQRNAPQAIAAPQTGFMRLLHLLAHSDWNGELFLLNFNSSWQEQQIGDLEHSFRSDRQSYPPLALATSYDQQHAGRLWTTGESPSLRILSHVSRLARHALEMIETSLQSKDLRFVRPAQLFRGSSEGYDLVIQLKSDLVPNALSYDLGSPFVSFDQPNYLLPRAGKDPLAAIVHQLRSAYSDYAAFFYNPHGGKELAIMWRPPAVFAPKAFKVTELQACTLCDKGKVQVVRETLVEDFKVLLKDFYLRISTPEELKREQREHQNPKRYFNAKPQDNESCSKSKKRKLAKAAKVQAPLKRKSLIKSRPLKSLS
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Nucleolar protein 6, Maternal transcript 89Ba.
What is the protein family that this protein belongs to?
Belongs to the NRAP family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HNT1_YEAST
Sequence: MEPLISAPYLTTTKMSAPATLDAACIFCKIIKSEIPSFKLIETKYSYAFLDIQPTAEGHALIIPKYHGAKLHDIPDEFLTDAMPIAKRLAKAMKLDTYNVLQNNGKIAHQEVDHVHFHLIPKRDEKSGLIVGWPAQETDFDKLGKLHKELLAKLEGSD
What is the function of this protein?
Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (PubMed:11805111).  Plays a role in the regulation of kinase KIN28 function (PubMed:10958787).  Essential for growth on galactose media at elevated temperatures (PubMed:11805111).
What are the official names of this protein?
Adenosine 5'-monophosphoramidase HNT1, Histidine triad nucleotide-binding protein HNT1, HINT, Hit family protein 1.
What is the protein family that this protein belongs to?
Belongs to the HINT family.
Protein: DXS_RHOCA
Sequence: MSATPSRTPHLDRVTGPADLKAMSIADLTALASEVRREIVEVVSQTGGHLGSSLGVVELTVALHAVFNSPGDKLIWDVGHQCYPHKILTGRRSRMLTLRQAGGISGFPKRSESPHDAFGAGHSSTSISAALGFAVGRELGQPVGDTIAIIGDGSITAGMAYEALNHAGHLKSRMFVILNDNDMSIAPPVGALQHYLNTIARQAPFAALKAAAEGIEMHLPGPVRDGARRARQMVTAMPGGATLFEELGFDYIGPVDGHDMAELVETLRVTRARASGPVLIHVCTTKGKGYAPAEGAEDKLHGVSKFDIETGKQKKSIPNAPNYTAVFGERLTEEAARDQAIVAVTAAMPTGTGLDIMQKRFPRRVFDVGIAEQHAVTFAAGMAAAGLKPFLALYSSFVQRGYDQLVHDVALQNLPVRLMIDRAGLVGQDGATHAGAFDVSMLANLPNFTVMAAADEAELCHMVVTAAAHDSGPIALRYPRGEGRGVEMPERGEVLEIGKGRVMTEGTEVAILSFGAHLAQALKAAEMLEAEGVSTTVADARFCRPLDTDLIDRLIEGHAALITLEQGAMGGFGAMVLHYLARTGQLEKGRAIRTMTLPDCYIDHGSPEEMYAWAGLTANDIRDTALAAARPSKSVRIVHSA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: TNAA_PHOLL
Sequence: MKRIPEPFRIKMVENIRMTTRAEREKALEEAGYNPFLLPSDAVYIDLLTDSGTGAMSDRQWAGIMMGDEAYAGSRNYYHLCDKVNELIGYQYTIPTHQGRGAEQILFPTLIARKKAQGGATHPVFISNFHFDTTAAHVELNGAKAINVVTSKAFDTTTYYDWKGDFDIDELEKTIAEHGADNVVAIITTVTCNSSGGQPISLANMKAVYEIAKQHDIPVVIDSARFCENAWFIKQREKGYENKSVKQIVKEMYQYGDMLTMSAKKDPLVNIGGLCCFRDDEDLFNEVRTRCVPMEGFVTYGGLAGRDMEALAIGLEEGMNEGYLAYRINQVAYLGNRLRDAGIPIQYPTGGHAVFVDAKLLLPHIPGEQFPAHALNNELYLEAGIRSVEIGSLLLGRDPKTGKQKPSPMELLRLTIPRRVYTNDHMDYVVEAFISLKERIPQIKGLTFTYEPSVLRHFVARLKPIK
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: CNOT9_RAT
Sequence: MHSLATAAPVPTALAQVDREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ
What is the function of this protein?
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Involved in down-regulation of MYB- and JUN-dependent transcription.  Enhances ligand-dependent transcriptional activity of nuclear hormone receptors.  May play a role in cell differentiation (By similarity).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 9, Cell differentiation protein RQCD1 homolog, Rcd-1.
What is the protein family that this protein belongs to?
Belongs to the CNOT9 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, P-body. Note=NANOS2 promotes its localization to P-body.
Protein: RLMN_PASMU
Sequence: MLEQQTCAEKAANTVNTVELSTDQAKKINLMNLTRQQMREFFKELGEKPFRADQLVKWIYHFGEDNFDNMTNINKKLRDKLKQVAEIKAPEVAVEQRSADGTIKWAMQVGDQQVETVYIPEADRATLCVSSQVGCALACTFCSTAQQGFNRNLTVSEIIGQVWRASKIIGNFGVTGVRPITNVVMMGMGEPLLNVANVVPAMEIMLDDFAYGLSKRRVTLSTSGVVPALDKLSEMIDVALAISLHAPNDELRDEIVPINKKYNIKMLMDSVNRYLSVSNANHGKVTIEYVMLDHVNDGVEHAHQLAQVLKNTPCKINLIPWNPFPEAPYAKSSNSRIDRFQKTLMEYGFTVIVRKTRGDDIDAACGQLAGDVIDRTKRTAQKKQFGQEIAVRNH
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUTA2_BACC0
Sequence: MKVSLFITCLSDVFFPQVGKSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAKQMIKAFEHSEYIVTPSGSCASMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNILGKNDWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGLDIKELPYCQDCCGFGGTFAVKMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRENKNIQVLHVAEVLAKGLNK
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A 2.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: COXX_OLEA2
Sequence: MLRAASSLFRFRVAGMVALSCVFGYLLAAGAAGPDMVTSAAGTFLLTCACSVFNQIQEKDLDARMPRTRNRPVASGRLPTTAARAVGMAALLPALILLHAAGGVRLVLLSAAVLALYNGVYTPMKKYTAFSLLAGAVPGALPPVFGWLAAGGNLYSPEIALLFIVYYLWQVPHFWLRAERDRQSYLAAGLPLPSVELPHRYHALLRLWYASYMVALLLLPVFPFIAETAVRIAVCLAGITGLAASGYLLASPVRGFHAVNVSMLFVMLLLVVDRLVTSGIIT
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLHD_PHOLL
Sequence: MSTVELLKHIYDINLSYLLLAQRLINHEKASAMFRLGISDSMADTLSELTLPQLVKLAETNQLVCNFRFEESETIQQLTRESRVDDLQQIHTGILLSTHLFQKLFSKKDDTSVKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAGK_STAHJ
Sequence: MRKCARIIYNPTSGKELFKRTLPDVLIKLERAGYETSAYATEREGDATLEAERALKRDYDIIIAAGGDGTLNEVVNGIAEQPNRPKLGIIPMGTVNDFGRALHLPSDIMGAVDVIIDDHTTKVDIGKMNNRYFINLAAGGQLTQVSYETPSRLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDNQVFQGEALLFLLGLTNSMAGFEKLVPDAKLDDGHFTLIIVEKANLAELGHIMTLASRGEHIKHPKVIYEKAKSINISSFTEMQLNVDGEYGGKLPANFLNLKRHIEVCTPKDIYNEELTEDQQVEDGIIEEKPSNEEIIKNNEISE
What is the function of this protein?
Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid.  Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway.
What are the official names of this protein?
Diacylglycerol kinase, DAG kinase, DAGK.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family.
Protein: LPXD_PARL1
Sequence: MADKRFFEAKEPLSLGEIAGRIGAALADADDGSRIVTGVAPLDTAGSNDLSFLDNPKYAEAFYATAAGACIVHPRFAERAPDNVALILSDQPYRAYALVAQIFHPDEAHGADTFGARGEIHPRATVHPTAKLGTGVTLEPGVTIGAGVEIGNNTVIGTNTSVGKGCTVGKDCFIGPNVTLSHAHLGDRVMVHPGVRIGQDGFGFAMGLPRHEKVPQLGRVIVQDDVEIGANSTVDRGAGPDTVIGEGTKIDNLVQIGHNVEIGRGCIIVSQTGIAGSTKLGDFVVLAAQVGVTGHLTINSGAQIAARGAVVHDVPAGQQYGGVPAKPIAEWRREVVELRKLGRRRRSGTKADD
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RDRP_CCMV
Sequence: MSKFIPEGETYHVPSFQWMFDQTLESDSHHDEAIFVTESINESGVDTSVEITADGTLASYMHAVKPLVEDGLLNPPFDQARWGLCCKNVVDVYDGLLGYRLIPMAEAARMLYLEIDGSFVDESECDDWRPVDTSDGFTEAMFDVMNEIPGEETKNTCALSLEAESRQAPETSDMVPSEYTLADRYVTTREEFASVDSDYDISLNLVSPVEFRVGVCEDTYRHSEADDPTMPQYHDRISLKSLEAAGHHMLPTHAYFDDTYYQALEELGDYNVDISKLSVRQSDVDWYRDPEKYYEPELSIGSFQRRIGTQKTVLTALKKRNADVPELADSVDIKRVACEVAEKFKRAYLNHSGIGLLGQSMDVMSRGLEYHKKWKDHKDLTGVTVLSEINLQRYQHMIKSDIKPVVSDTLHLERAVAATITFHGKGVTSCFSPYFTACFEKFSKALKSRFVVPIGKISSLELKNVPLSNKWFLEADLSKFDKSQGELHLEFQREILLSLGFPAPLTNWWCDFHRESMLSDPHAGVNMPVSFQRRTGDAFTYFGNTLVTMAMMAYCCDMNTVDCAIFSGDDSLLICKSKPHLDANVFQSLFNMEIKVMDPSLPYVCSKFLLETEMNNLVSVPDPMREIQRLAKRKIIKSPELLRAHFESFCDRMKFLNKLDEKMINLLCKFVALKYKKPDVENDVRVAIAAFGYYSENFLRFCECYATEGVNIYKVKHPITQEWFEASRDRDGDWFHDWRNPKFPTALDKVWRFFGKYARDDPMKHIEERDRRHRLNRAMNSSLKLAYDRRSLSKDKETVAWVRKTLSK
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome composed of 3 RNA segments, RNA1, RNA2 and RNA3.
What are the official names of this protein?
RNA-directed RNA polymerase 2a, protein 2a.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: KCY_PROMH
Sequence: MAVIVPVITVDGPSGAGKGTLCQALAKAFGWHLLDSGAIYRVLALAALHHHVDITSEDALVPLAANLDVRFIPNENGLSVILEGEDVSTEIRTETVGNTASQAATFPRVREALLRRQRAFRTAPGLIADGRDMGTIVFPDAQVKIFLDASAQERARRRMLQLQEKGFNVNFERLLSEIKERDYRDRNRAVAPLVAAKDALILDSTSLSIDEVIEKSLAYAKKICN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_SHESM
Sequence: MTALTQMKCEACQADAPKVTDEELAELIRMIPDWGVQVRDGIMQLERVYKFKNFKLAMAFTNKLADLAEEEFHHPGILTEWGKVTVTWWSHSIKGLHKNDFIMAAKTDQLLD
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: GLGC_ACET2
Sequence: MHKKEIIALLLAGGQGSRLGVLTKNIAKPAVLYGGKYRIIDFSLSNCVNSDIDTVGVLTQYQPLELNAHIGIGKPWDMDRINGGVTILSPYLKAEIGEWYKGTANAVFQNIHYVDKYSPKYVIILSGDHVYKMNYSQMLDFHKENNADATISVINVPWEEASRYGIMNTYENGKIYEFEEKPQNPKSNLASMGVYIFNWEVLKEYLIRDDQNEESAHDFGKNIIPMMLKEGRSMWAYKFNGYWRDVGTIQAYWESNMDLISRVPEFNLFDPAWKIYTPNPVKPAHYIGPTGSVKKSIVAEGCMIYGSVRNSVLFPGVYVSEGAEIVDSIVMSDSVIGENTQIYKCIIGEEVKVGKNVRMGIGENIPNELKPHLYDSGITVVGEKAVVPDGCQIGKNVVIDPYITAEEFPSLNIESAKSVLKGGETE
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: GPMI_COLP3
Sequence: MANKKSTVLMILDGWGYREETSSNAIHQANTPVLDNLKAKYPNMLIDTSGMAVGLPEGQMGNSEVGHVNLGAGRVVYQDFTRITKAISDGDFIENPTLCHAVDTATSNNKAVHIFGLLSPGGVHSHEEHIFAMMELAKKRGAQKVYLHAFLDGRDTPPRSAQASLEKAQQKFSKLFTETDTGEGQIASVIGRYYAMDRDQRWDRVEAAYNLMVNGEGLHQYNSALDALAAAYERNENDEFVGASAITSPSGKAIKVNDGDALIFMNFRADRARQFSRCFTDTNFNGFERKRIPAISNFVMLTQYAADIDAPSAFAPTPLTNVMGEWLAKHNKTQLRISETEKYAHVTFFFSGGKEDMFTGEERILVPSPDVATYDLQPEMNSTLLTDKLVGAIESGKYDFIVCNYPNGDMVGHTGSFDAAVKACEAVDTCVGRVVKAAQDNGGECLITADHGNAEQMQDPVSGQAHTAHTCEPVPLIYVGRNASPAASGTLSDISPSVLHLMGMEQPQEMTGSVLMQLIK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: TYSY_EXISA
Sequence: MKQYHDLCRHILDQGVVKEDRTGTGTTSVFGYQMRFNLQEGFPLITTKKLHIRSIIHELLWFISGETNVRYLQDNGVRIWNEWADEEGNLGPVYGSQWRSFPRPDGSSVDQLAQVIEQIKTNPDSRRLIVSAWNPGQLEEMALPPCHLLFQFYVADGKLSCQLYQRSADTFLGVPFNIASYALLTHMVAHVTGLEVGDFVHTLGDAHIYHNHLEQVELQLSRDPRPLPKLNIVRDVSSIESFRFEDFEILGYDPHPHIKGEVSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_SYMTH
Sequence: MKPIVAIVGRPNVGKSTLFNRLTQSRHAIVEDQPGVTRDRLYADTEWNGRTLTLVDTGGIQLDKEGDTIEAHVTRQAELAIREADVIIFVVDVTDGVTAPDLEVADLLRRQRKPVIVAVNKVENLKREDEALEFWALGLEPLINVSAEHGLGTGDLLDAVVAALPDLSEPEPEEGGPVRVAVIGRPNVGKSSLVNAILGEERVIVSDVPGTTRDAIDVLVERGEDKFLLIDTAGMRRKARVEEAVERYSVMRALRAVERAQVVLIVIDAQDGVTEQDQRIAGYAHENGKACIVVVNKWDLIEKDDRTMAKMTEEVRMRLAFMDYAMIHFVSAKTRARVHRLLPLIKEAAANHARRISTRELNDLVREAVALNPPPSDKGRRLKIFYATQPHVSPPGFVFFVNDSELVHFSYQRYLENQLRQTYAFEGTPINLYFRTREKAKLGERPVRVRRVLAGGQTREIRRAARKRSTE
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.