PharMolix/UniProtQA huggingface dataset:
Protein: PGA18_CANAL
Sequence: MKLESIAVFAGIVSTALAGVYHKPPPATTYWTTIYAPSTSVVTVTSCSKGGCGTQSYATGVTKTKTVHEGVTTEYTTYCPLTTSHEVVKSTCSDTLVVWSTRSFSWVWSFSKPDGCGQSTSTIKTTAQTDVPTTATATPSVSTTCTTGTKTKWWWVIKTTDCSVYTVSSTSSSLISTSQVTSSSSIASTTATAPATPSVSTTCTTGTKTKWWWVIKTTDCSVYTVSSTLSSLISTSKATSSSSVASSTGSTPATTPGSSIESTPATTPGSSTESTPATATGSSTKSTPATTPGSSVTTGKTSTDWITSFTTHTAHTTTVITVTDCDHHSCTSNVVTTGVTVVTVTTTGTVTEYTTYCPLTSTETIVTSKTTSATTPGSSSVESTPGSSSATTPGSSSATTPGSSSATTPGSSSATTPGLSSVESTPGSSSATTPGSSSATTPGSSSATTPGSSSATTPGTSSVESTPGSSSATTPGSSTIESTSGSSSATTPGSSSATTPGSSSATTPGTSSVESTPGSSSATTPGSSTIESTSGSSSATTPGSSSATTPGTSSVESTPGTSTGSCWVSVSTGGYGYETTVTICSDVTSGQSVTTPTTISVPSTFCTTVPTAGTDETVITSYVTSTAHSTEVITVTSCADNGCQTHTTHTGVVVVTVTTTDVATTYTTYCPLTTTKAVYRVAKLANYKRDQTEFIATETNENTSNWPAPTLVPYVGISNDSSAAVSTFEGAANSVVPRLGLIAGFLSALLFLF
What is the function of this protein?
Cell wall protein which mediates cell-cell and cell-substrate adhesion.  Required for biofilm formation and plays a role in virulence (By similarity).
What are the official names of this protein?
Probable GPI-anchored adhesin-like protein PGA18, Predicted GPI-anchored protein 18.
What is the protein family that this protein belongs to?
Belongs to the PGA18 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Protein: RECO_CHLTB
Sequence: MQITLPGVVLTNSPAEKQHVIVKIFSPAGLLSAFAKNGASLSCDFRESLFPISFSLFTIQQSPPKMRKVIQGELQNPFTTIKSSYPLLQSAGKMIQAILKTQWHEKPSPHLFSLFFNFLQRIPETQYPNFFSSMFLLKLLQHEGSLDLSRSCTLCKTSLESSTIYRYEGALFCEKHAHEETISFSQEEDHILRVIVQAKKFQELVCLAEFPIDIDTKIDALFSSFLSETSEPSSLYYKGKTLL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: CBR1_BOVIN
Sequence: MSSSNCVALVTGANKGIGFVIVRDLCRRFSGDVVLTARDEARGRAAVQQLQAEGLSPLFHQLDIDDRQSIRALRDFLRKEYGGLDVLVNNAGIAFKTADTTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSFVSVNSLKKCSRELQQKFRSETITEEELVGLMNKFVEDTKNGVHRKEGWPDTAYGVTKIGVTVLSRIHARKLSEQRGGDKILLNACCPGWVRTDMGGPKASKSPEEGAETPVYLALLPSDAEGPHGEFISEKRVVQW
What is the function of this protein?
NADPH-dependent reductase with broad substrate specificity.  Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics.  Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol (By similarity).  Can convert prostaglandin E to prostaglandin F2-alpha (By similarity).  Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates.  Catalyzes the reduction of S-nitrosoglutathione.  In addition, participates in the glucocorticoid metabolism by catalyzing the NADPH-dependent cortisol/corticosterone into 20beta-dihydrocortisol (20b-DHF) or 20beta-corticosterone (20b-DHB), which are weak agonists of NR3C1 and NR3C2 in adipose tissue (By similarity).
What are the official names of this protein?
Carbonyl reductase [NADPH] 1, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], 20-beta-hydroxysteroid dehydrogenase, Alcohol dehydrogenase [NAD(P)+] CBR1, NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, PG-9-KR, Prostaglandin-E(2) 9-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_PSEE4
Sequence: MLQPKRTKFRKQMTGHNRGLALRGSKVSFGEFALKAVARGRLTARQIESARRALTRHVKRGGKIWIRVFPDKPVTKKPLEVRMGKGKGSVEYWVAQIQPGKVLYEIEGVSEELAREAFALAAAKLPLATSFVKRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: AROB_WOLSU
Sequence: MKKIEIELNERSYPIHLGTMECLEHAGAVLVVTNPKVGGLYLSYVLERIRAREVFVCTTPDGEAYKTLESVEMILESAFNHRLDRKSLMIALGGGVIGDMVGFASGIFQRGIGFVQIPTTLLSQVDASVGGKTGVNNAFGKNLIGLFHQPKAVYIDPLFLKSLPPREFGAGVAEMVKMAVTFDREFFEELERGDLRDHSFLLKGIERCVKIKARVVAMDEREQGIRAALNYGHTFGHVIEHESGYGHYLHGEAVGMGMVMANTLACGLGLLKESEAERIEKLLARYEIPTRYAIGDVERFYDLFFLDKKSENQKIKFILPEGIGGVAFRDDLSKSMVLSVLEAFCD
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLF1_EPIUN
Sequence: MTLTNLDVIVVGAGFSGILAVYRLRKLGFRVQGFERQERLGGVWRENAYPGAAVDSLFPFYQFYDAELLQDWEWVEQFPTRAEMLRYFDHVDKRWEISASFEFGVSVSAARYSETTQRWTVSLEDGRRAEARWFIPAVGFSSVLNIPRIPGMSRFRGPIYHTAKWPHDAVSMRGKRVAVIGTGPSGVQIIQSVGKIAKAMTIFQQSPCLTLRKYGSPSQTATALCMRPDDHREALRLGLQTSNGFGYVPRDQDTLDVPIEERNHFYQQRYLAGGWAFWMAGFRDLCQNIQANRDAYDFWARRTRARISDVAKRELLVPQIPSFAFGIKRPCLEEDLYEVMDQPHVKVIDISNQQIELITETGIRVHGQTVECEAIILATGFGDEASGLRSLHIRGRNGIRLEDAWSDGVESHLGMAIHSFPNMVILYGPQCPTLLVNSPAVITVQVEWLCEIIARCQQAGICQLEATSKSHCQWERKMSLLWDKTLYHTHARKSKKTAEANKEEKTWVGGLILYRRELENCLANNLEGFQAWHVEETGLL
What is the function of this protein?
FAD-binding monooxygenase; part of the gene cluster that mediates the biosynthesis of loline alkaloids, potent insecticidal agents composed of a pyrrolizidine ring system and an uncommon ether bridge linking carbons 2 and 7 (PubMed:15654104).  Lolines are structurally differentiated by the various modifications of the L-amino group and include norloline, loline, N-methylloline, N-acetylloline, N-acetylnorloline, and N-formylloline (PubMed:15861432, PubMed:25531527).  The first committed step is the condensation of O-acetyl-L-homoserine (derived from L-aspartic acid) and L-proline, probably catalyzed by the gamma-type pyridoxal 5'-phosphate(PLP)-dependent enzyme lolC, to give the diamino diacid, NACPP (PubMed:15861432, PubMed:16755627).  Ensuing cyclization, decarboxylation, and acetylation steps yield 1-exo-acetamidopyrrolizidine (AcAP)(PubMed:24374065).  LolO is required for installation of the ether bridge upon the pathway intermediate, 1-exo-acetamidopyrrolizidine (AcAP) (PubMed:29537853).  In sequential 2-oxoglutarate- and O(2)-consuming steps, lolO removes hydrogens from C2 and C7 of AcAP to form both carbon-oxygen bonds in N-acetylnorloline (NANL), the precursor to all other lolines (PubMed:24374065, PubMed:29537853).  The enzymes lolD, lolE, lolF and lolT have also been proposed to be involved in the ether-bridge installation (PubMed:15654104).  Further processing of the exocyclic moiety of NANL by fungal N-acetamidase (LolN), methyltransferase (LolM), and cytochrome P450 (LolP) enzymes, with occasional involvement of a plant acetyltransferase, generates the other known lolines (PubMed:25531527, PubMed:18655839).  LolN transforms NANL to norlonine which is monomethylated and dimethylated to respectively lonine and N-methyllonine (NML) by lolM (PubMed:25531527).  LolP catalyzes hydroxylation of the methyl group in N-methylloline (NML) and further oxygenation to N-formylloline (NFL) (PubMed:18655839).  A plant acetyltransferase is responsible for the acetylation of loline to form N-acetylloline (NAL) (PubMed:25531527).  LolA might interact with aspartate kinase to prevent feedback inhibition of its activity by these end products and thereby promote production of L-homoserine from L-aspartate (PubMed:15654104).
What are the official names of this protein?
FAD-binding monooxygenase lolF1, Loline biosynthesis cluster 1 protein F.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
Protein: YAAA_ECOL5
Sequence: MLILISPAKTLDYQSPLTTTRYTLPELLDNAQQLIHEARKLTPPQISSLMRISDKLAGINAARFHDWQPNFTPENARQAILAFKGDVYTGLQAETFSEDDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALAAQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRFIIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: LPXB_RICCN
Sequence: MIKIYFIAGEVSGDFVGGRIMQHLKNNTGVQLNSPVSSFVNDAVQFVGVGGKYMEEAGSFKSLFPITSINLMGFVEILPHIFKLKKLIDKTVEDIINSKADLLITIDSPGFTYRVAKRVRKLLPKLKMIHIVAPSVWAYKEGRAVKYAKIYDCLFALLPFEPPYFTKVGLDCRYIGHPIMEQEFYSDKIALREEFKIDENERVLCVTLGSRKGEILRHLSVFVSSIEEIFKSCNNLKVIFTLANPAHEAIIKPFLEDVKFNYLFSSERLKIYAVADVALAKSGTNTLEIAASGTPMIVAYKVNLISFFIIRLLIKIKYVTLINIIADKEIIPEFIQFNCRANLISNKLQELLFNSKKAYEQVIESQKILQQLGFKSNRLQLNSESFRHDEFKGKLARCTKVREHRLSLENSLVSSDRDDAVPSYIAAAIIKQEFLEPKIKLLKEKD
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: S10AB_MOUSE
Sequence: MPTETERCIESLIAVFQKYSGKDGNNTQLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNCDGQLDFQEFLNLIGGLAIACHDSFIQTSQKRI
What is the function of this protein?
Facilitates the differentiation and the cornification of keratinocytes.
What are the official names of this protein?
Protein S100-A11, Calgizzarin, Endothelial monocyte-activating polypeptide, EMAP, Protein S100-C, S100 calcium-binding protein A11.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RK22_MARPO
Sequence: MQTNTSNKKIRAVAKHIHMSPHKVRRVVSQIRGRSYEQALMILEFMPYRACNPILQLLSSAAANANHNFGLSKTNLFISEIQVNKGTFFKRFQPRAQGRGYPIHKPTCHITIVLNILPK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y4IF_SINFN
Sequence: MSGALLWAKAEAQRISSALVTGTTNMVDAELKLAQKLHGRVRDYVQWHHQDERCRKGISVLEYGPGTVRAFQQKTLPLVIGLRGETSRCTLVDRSREFLGDIAQLSSALGLKIEFIRGDIFSGRRYFCDDEAAFIVMFGRTFGNLAVPTNDTHPMEAVVETLKKISNSAKRCWVAISIGSDLRRDVAKSYYEAHPEFQLNVFYRMKAELPVDGNFDPEAFEYEPDVIGGDQFMQVIHTAVVKKNLDFCIGGKDIILLSGERLHLKNSFCFSESFFKKCAHRAGFVPIDVLSDDAGSAIHVLQKVN
What are the official names of this protein?
Uncharacterized protein y4iF.
Protein: Y526_CHLPN
Sequence: MPSPMISTDVCQDILGKQKEAVDFFFQAFQPKEAMQLAEKILGHSGWVFFSGVGKSGCVARKLVATLQSLSERALFFSPVDLLHGDLGLVSPGDIVCLFSKSGETQELLDTVPHLKSRRAILVAITSMPYSNLAALSDLVVILPSVAELDPFNLIPTNSTTCQMIFGDFLAMLLFHSRGVSLSTYGKNHPSGQVGMKANGKVKDFMFPKTEVPFCHLGDKVSFSLEVFSAYGCGCVCIVDPQFRLMGIFTDGDLRRSLASYGGEVLSLSLEKVMTANPRCITEDSDIAIALQLMESSSPVAVLPVLDNEENRHVTGLLHMHTLAKAGLL
What are the official names of this protein?
Uncharacterized protein CPn_0526/CP_0226/CPj0526/CpB0547.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GutQ/KpsF subfamily.
Protein: RHLB_HISS2
Sequence: MQNSHLSQQRFSDLALHRIVQQAIKEKGFEFCTPIQALSLPITLKGQDIAGQAQTGTGKTIAFLTATFHHLLQKNNINSSEQPRALILAPTRELVVQIANDANFLVQATGLKTGLAYGGEGYDKQLKVIDRGIDILIGTTGRVIDYVKQGIIRLDYIQVVVLDEADRMFDLGFIRDIRYLLRKCPVPQQRLTMLFSATLSYKVRELAFEHMNDPQYVEIEPLQKTGHRIREELFYPSNQDKMALLMTLLEEEWPERCIIFSNTKHRCEEIWGYLSADGHRVGLLTGDVMQKKRLSLLKQFTDGTLDVLVATDVAARGLHIPDVTHVFNYDLPDDCEDYVHRIGRTGRAGESGISISFACEEYAINLPAIEEYIGHSIPVSQYDAKALIEDLPTPHRIKRGAFDSRSNLQRTVKRLKKTY
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y318_MYCPN
Sequence: MAVASKKFTERQFLFFVVNYIAGFGFISTALSLFELGPLSWVIFFLVSLISLIVTLAFARVSAIDKNNYGGAYLWAKKAFNSERYSHRLFIFFTGWNNFIASPLYAAIAPLFILSAFKGIDGIQGNAANTWILIAAGFTFYLLLAFLSTKGTSLNKKLIAVFASIKWAVLLSTLIVALIVIGKNGNGYAINNDIKQGPFKEREITLGAVATVFITFFYSYSGAEDISTMTPDVKTTNFRKILIISFIAVFLFYFVGILIFNGLLNVSQSDDDKGKDGRIASVADIFRLAGGLGALIFYGVGALFNNVSTRLSTIIANSRKILPLAQDNYLPTTFSKANSKGEFQNAIWFTFGTTIITMTVLFFVPLITSNFDFDKSTEYASSIGSAATLVQYILVFFIIFRLIYKKEQLYQKNWTRELEQILFGIGVFIILLMLLFYLFPVIDGKTKWQLKNTLTLVVYGVLILIGFALFMTQEYKRNKQKESYVTPRAVT
What are the official names of this protein?
Uncharacterized protein MG225 homolog.
What is the protein family that this protein belongs to?
To M.genitalium MG226.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL19_BACC1
Sequence: MQQLIAEITKGQLKTDLPSFRPGDTLRVHVKVVEGTRERIQLFEGVVIKRRGGGISETFTVRKISYGVGVERTFPVHTPRIAKIEVLRRGKVRRAKLYYLRNLRGKKARIKEIR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: XERD_STAAR
Sequence: METIIEEYLRFIQIEKGLSSNTIGAYRRDLKKYQDYMTEHHISHIDFIDRQLIQECLGHLIDQGQSAKSIARFISTIRSFHQFAIREKYAAKDPTVLLDSPKYDKKLPDVLNVDEVLALLETPDLNKINGYRDRTMLELLYATGMRVSELIHLELENVNLIMGFVRVFGKGDKERIVPLGDAVIEYLTTYIETIRPQLLKKTVTEVLFLNMHGKPLSRQAIWKMIKQNGVKANIKKTLTPHTLRHSFATHLLENGADLRAVQEMLGHSDISTTQLYTHVSKSQIRKMYNQFHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQP2_DUGDU
Sequence: SIAFSRAVFSEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLAIGTLVQALGHISGAHINPAVTVACLVGCHVSFLRATFYLAAQLLGAVAGAAILHEITPPDIRG
What is the function of this protein?
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
What are the official names of this protein?
Aquaporin-2, AQP-2, ADH water channel, Aquaporin-CD, AQP-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated.
Protein: CWC2_DEBHA
Sequence: MSYREPLGEYDCHIDNTRNMPPDTTIVSKSKKGKPARLQVDPESIPDDDRPPQTGNVFNIWFLKWSGGDSSTKNYTKSKFRVNIKKDSGYTKAPSNAPLCLFFARGCCYLGKKCSYYHRLPSDTDYFIPTQDCFGRDKTSDYKDDMNGVGSFSKSNRTLYIGGLHMDDKMENTLTKHFQEFGSIDKIRVLHSKACAFVTFRTENEAQFAKEAMQNQSLDGNEVLNIRWANEDPNPEAQRQEKRRLEEVTVNTVKNLLDSVSQTERKTKKVTVEVPDEIEETESSSEIKALPSSETSSGLFNNSSLNALKQFQSKKRKIDKPQPKENLPTMLGYSSSDEE
What is the function of this protein?
Involved in the first step of pre-mRNA splicing.  Required for cell growth and cell cycle control.  Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex.  May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA.  Associates predominantly with U6 snRNAs in assembled active spliceosomes.  Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor CWC2.
What is the protein family that this protein belongs to?
Belongs to the RRM CWC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGK2_HUMAN
Sequence: MSLSKKLTLDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVLMSHLGRPDGVPMPDKYSLAPVAVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLENLRFHVEEEGKGQDPSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPHKASGFLMKKELDYFAKALENPVRPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGMAYTFLKVLNNMEIGASLFDEEGAKIVKDIMAKAQKNGVRITFPVDFVTGDKFDENAQVGKATVASGISPGWMGLDCGPESNKNHAQVVAQARLIVWNGPLGVFEWDAFAKGTKALMDEIVKATSKGCITVIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKILPGVEALSNM
What is the function of this protein?
Essential for sperm motility and male fertility (PubMed:26677959).  Not required for the completion of spermatogenesis (By similarity).
What are the official names of this protein?
Phosphoglycerate kinase 2, Phosphoglycerate kinase, testis specific.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_PSEP1
Sequence: MQHYVTPDLCDAYPDLVQVLEPMFSNFGGRDSFGGQIVTIKCFEDNSLVKEQVELDGKGKVLVVDGGGSLRRALLGDMLAEKAAKNGWEGLVIYGCVRDVDVLIQTDVGVQALASHPMKTDKRGIGDLNVVVTFAGVTFRPGEYVYADNNGVLVSPSPLKMPE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: YPUI_BACSU
Sequence: MKEAKCERQIHEGKIPNEMGHSIVRAQTQKTGEFLSMVVNTVNDYLNQTTLESLQAELPIEKGYCCDVLSTLRRMAVFCEGGAEACRRLLMQEPFQEARAEKTLYNVYHQCIEEFFMPKKDTWCENSRASYTGVSAIEFYHAVPASLEQLLLPLSAAFLKMREELAHYEASGSSMAPIR
What are the official names of this protein?
Uncharacterized protein YpuI, ORFX9.
Protein: SYTC1_DICDI
Sequence: MSDSQENKPVETPTEVKPVAEKKPAAEKKEKKPAVKKVGVMETLQTPDYVKERIEIWESLKAKHLESLKDMKEEPINVTLPDGKVVAGIKNKTTPYDIAKGISRGLADSIVSSKVNGEQIWDISRPLEADCNLQLCKFDSEEGKKTFWHSSAHILGQAMERIYGGQLCIGPATSEGFYYDMAMGDKIVSAEDYKLINEVAQKIVQEKQPFERLAVPRDIALTMFKFNKYKTEIISKIPQEDTVSLYRCGTLVDLCRGPHVPNTSYIKSFAVTKNSSAYWLGKAENDDLQRVYGISFPDKKQMEEYENFMREAALRDHRNVGKAQELFFFHPYSPGSAFFLPHGTRIYNKLVEFIREEYHRRGFTEVISPSIFSQKLWEQSGHWQKYSENMFVLPVDKDNFSLKPMNCPGHCLMFGSRQRSYRELPLRFADFGVLHRNELAGALTGLTRVRKFQQDDAHIFCTTEMIEDEINSCLGFMQYVYGIFGFEFGLELSTRPDNFLGEIAQWDIAEASLEKALNKFGKPWKLNPKDGAFYGPKIDIHITDCLKRSHQCATIQLDFQLPIRFDLEYQSDDAAELKKRPVIIHRAILGSVERMMAILIEHTGGKWPLWVSPRQAIVVTVNKTHNEYGQKVCKEISDAGFYCDIDDSDKTISKKVREAQLAQYNYILVVGQEEINGNTVNVRTRDNVVRGSLTVNDLISEFKQLVKEFK
What are the official names of this protein?
Probable threonine--tRNA ligase 1, cytoplasmic, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAG_HV2NZ
Sequence: MGARNSVLRGKKADELEKIRLRPGGKKKYKLKHIVWAANELDRFGLAESLLESKEGCQKILTVLDPLVPTGSENLKSLFNTVCVIWCIHAEEKVKDTEGAKQIVQRHLVAETGTAEKMPNTSRPTAPPSGKNFPVQQVAGNYTHIPLSPGTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIREIINEEAADWDVAHPIPGPLPAGQLREPRGSDIAGTTSTVEEQIQWMFRPQNPVPVGNIYRRWIQIGLQKCVRMYNPTNILDINQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMTQTLLIQNANPDCKLVLKGLGMNPTLEEMLTTCQGVGGPGQKARLMAEALKEVMAPAPIPFAAAQQRKTFKCWNCGKEGHSARQWSAPRRQGCWKCGKSGHVMANCPDRQAGFLGIGHWGKKARNFPAAQVPQGLTPTAPPLDPAVDLLEKYMQQGKRQREQRERPYKEVTEDLLRFEQAETPCRETTEDLLHLNSLFGKDQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: ACP_BUCBP
Sequence: MQNIEKKIKKIIAQQLGLIEQKITNESLLVEDLNADSLDIVELIMAFEEEFNIEITDEEAENLTSVQSIFDIIKKYVF
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPI1_ASPCL
Sequence: MSRTQQAPMNAGSASGVQVASPLSQDNSTIRVSGTLRLRGDNGTRNNGEDLTTTRHIRWSEDVVDNEGMGKKSSKVCCIYHKDRPVGESSSESDDTDSSSDDCSDCDSDTRIPTHKGDQGGEASSRCSPSRLAERKCGTSCSKRHSKQRSRRHMSPNAYEKMPKFKGQPGKR
What is the function of this protein?
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
What are the official names of this protein?
Type 1 phosphatases regulator ypi1.
What is the protein family that this protein belongs to?
Belongs to the YPI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KEN2_CULQU
Sequence: MEVLKLCLLLTRKKQFEVELIPEKIGARRPWKLETSSTATEAVVSVVTYLEATSGNARDAKEAGIYIRVYGAGWMIPEFVRMLMLHYSKHGECILQEIGAAFRGEHATDLLLICDGKETVRAHKLVLAAASPLIRMILEETPVLDGVTTVYFPEVQVSYFRLLLDFLYSGQVYVRSVEEYHHLQDLLALLQIKASIWKNSDGSDAGEPRKSEPLVDINRNTEGITGSSVVHQHPSRRRRSKSQDSLSGDSASGGGGTGSQAGTPKKVSVKSERHSAGSSVDGDGDRDREENLEYLDEVEEAIIKSNNNHPLHPHQHHLVAGSGGHHLHHHHHHHHRQLHQISRHDGDDDAGGGSGNDGASEGGSGESGRAGSVAGESAGDRPTPTNLSSGGGGAGSGRRSGSGEPTEPAEDDEDYELDVEDRGGDGDEAAGEGETRSRRSDPSANRRRSSSDPVNLSIVKQQQDVDSDDANIDVETIGTATTKTLLPPRYLDPFRTKRKAAAYYIHPADAEALKPMDHEGLLHNSPDNYVVTPHRKRRPGFHNSPAQNPPFVPSYLDDLRARSKCFLSAPPTYLPEKYLSVLTRWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRNIINAPEAGGRYTCCFCSLVFETLQELVRHLSGHHNNLLLSKNLHE
What is the function of this protein?
Transcription factor required for terminalia development.  Negative regulator of the JAK/STAT pathway: represses JAK/STAT-dependent expression of ventral veins lacking (vvl) in the posterior spiracles (By similarity).
What are the official names of this protein?
Transcription factor Ken 2.
What are the subcellular locations of this protein?
Nucleus.