PharMolix/UniProtQA huggingface dataset:
Protein: HSP27_DROME
Sequence: MSIIPLLHLARELDHDYRTDWGHLLEDDFGFGVHAHDLFHPRRLLLPNTLGLGRRRYSPYERSHGHHNQMSRRASGGPNALLPAVGKDGFQVCMDVSQFKPNELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLPKGFDPNEVVSTVSSDGVLTLKAPPPPSKEQAKSERIVQIQQTGPAHLSVKAPAPEAGDGKAENGSGEKMETSK
What are the official names of this protein?
Heat shock protein 27.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: UPPP_NEIMB
Sequence: MDFLIVLKALMMGLVEGFTEFLPISSTGHLIVFGNLIGFHSNHKVFEIAIQLGAVLAVVFEYRQRFSNVLHGLGKDRKANRFVLNLAIAFIPAAVMGLLFGKQIKEYLFNPLSVAVMLVLGGFFILWVEKRQSRAEPKIADVDALRPIDALMIGVAQVFALVPGTSRSGSTIMGGMLWGIERKTATEFSFFLAVPMMVAATAYDVLKHYRFFTLHDVGLILIGFIAAFVSGLVAVKALLRFVSKKNYIPFAYYRIVFGIAIIILWLSGWISWE
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PP311_ARATH
Sequence: MTLPPPIASTAANTILEKLSFCKSLNHIKQLHAHILRTVINHKLNSFLFNLSVSSSSINLSYALNVFSSIPSPPESIVFNPFLRDLSRSSEPRATILFYQRIRHVGGRLDQFSFLPILKAVSKVSALFEGMELHGVAFKIATLCDPFVETGFMDMYASCGRINYARNVFDEMSHRDVVTWNTMIERYCRFGLVDEAFKLFEEMKDSNVMPDEMILCNIVSACGRTGNMRYNRAIYEFLIENDVRMDTHLLTALVTMYAGAGCMDMAREFFRKMSVRNLFVSTAMVSGYSKCGRLDDAQVIFDQTEKKDLVCWTTMISAYVESDYPQEALRVFEEMCCSGIKPDVVSMFSVISACANLGILDKAKWVHSCIHVNGLESELSINNALINMYAKCGGLDATRDVFEKMPRRNVVSWSSMINALSMHGEASDALSLFARMKQENVEPNEVTFVGVLYGCSHSGLVEEGKKIFASMTDEYNITPKLEHYGCMVDLFGRANLLREALEVIESMPVASNVVIWGSLMSACRIHGELELGKFAAKRILELEPDHDGALVLMSNIYAREQRWEDVRNIRRVMEEKNVFKEKGLSRIDQNGKSHEFLIGDKRHKQSNEIYAKLDEVVSKLKLAGYVPDCGSVLVDVEEEEKKDLVLWHSEKLALCFGLMNEEKEEEKDSCGVIRIVKNLRVCEDCHLFFKLVSKVYEREIIVRDRTRFHCYKNGLCSCRDYW
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g14820.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
Protein: TRMD_CLOK1
Sequence: MDVKIDILTLFPEMFHVFNYSIIGRAIEKNILSINTFNIRNFTENKHRKVDDYPYGGGSGMIMTAQPIVDCINSVKTQNKGNVVYLGPRGKIFDQSMAKKLSSEKELIFLCGHYEGIDERVYRYIDLEISIGDFIVTGGEMACIPIVDSICRMIPGVLSSTESYTEESFYNGVLEYPQYTRPEFFRGDRVPEVLISGHHENIRKWRRAKSFILTKNKRPDLFERIELSKEDRELIKLYENGYTD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCDB_NOCSJ
Sequence: MLLSDRDILVEIDAGRVALEPYDPGMLQPSSIDVRLDRFFRVFENHKYPHIDPAADQSDLTRMVEPEGDEPFILHPGEFVLGSTYEVVTLPDDIAARVEGKSSLGRLGLLTHATAGFVDPGFSGHVTLELANVATLPIKLYPGMKIGQFCFFRLSSPSEHPYGSAKYGSRYQGQRGPTPSRSYQNFHRTPI
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PURA_PROM9
Sequence: MANVVVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTIVVDDKVLKLHLIPSGILYKNKTCLIGSGTVVDPKILLKEIDMLIDNEIDISGLKLSSTSHVTMPYHRILDEAMEADRGSNKIGTTGRGIGPTYADKSQRNGIRVRDLLNKERLRDVIEIPLREKNGLLEKIYGIKPLKTEDIVEEYLDYGERLSKHVVDCTRTIHSASKNKKNILFEGAQGTLLDLDHGTYPFVTSSNPISGGACIGAGVGPTLIDRVIGVAKAYTTRVGEGPFPTELQGSINDQLCDRGSEFGTTTGRRRRCGWFDGVIGKYAVSVNGLDCLAVTKLDVLDELDEIQVCIAYDLDGERIDYFPTNSDDLKKCKPIFKKLKGWQCSTANCRNLSDLPQNAMNYLRFLAELMEVPIAIVSLGANRDQTIVIEDPIHGPKRALLR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STX7_SCOVN
Sequence: FKSLTKYSPGRQN
What are the official names of this protein?
Scolopendra 6940.74 Da toxin.
What is the protein family that this protein belongs to?
Belongs to the scolopendra toxin 7 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CA1A_CONAE
Sequence: SDGRNVAAKAFHRIGRTIRDECCSNPACRVNNPHVCRRR
What is the function of this protein?
Acts as a competitive inhibitor and is 33-fold more potent on alpha-7/CHRNA7 nAChRs (IC(50)=1. 8 nM) than on alpha-3-beta-2/CHRNA3-CHRNB2 nAChR (IC(50)=60. 1 nM).
What are the official names of this protein?
Alpha-conotoxin ArIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GRPE_ALIF1
Sequence: MSNEENKVNEEAVVEEQVEAVGTEADVEWNESAEDSQEAKIAELEAALLASQAQVKEQQDTVLRAKAEEQNVRRRAEEDVDKARKYALKKFAGELLPVLDNLERALESGDKENEAAKALLEGVELTLQTFVSTVEKFGLTVINPMGEAFNPELHQAIGMQASPDHESNTVMIVMQKGYTLNDQVLRPAMVMVAQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILL9_ORYSJ
Sequence: MAASSSSTTRLIPLLLVLTFCLALASASAWAAAAGDDDLLAAAREPGMAEWLRGVRRRIHRHPELAFEEVRTSELVRAELDAIGVPYQWPVARTGVVATIAGGGGGDGPVVALRADMDALPVQELVDWEHKSQENGKMHACGHDAHTAMLLGAAKLLQKRKNELKGTVKLVFQPAEEGSAGAYYVLQEGVLDDVSAMFGMHVDPALPVGVVAARPGPFAATSGRFLATITGKGGHAAFPHDAIDPVVAASNAILSLQQIVAREIDPLQGAVVSITFVKGGEAYNVIPQSVEFGGTMRSMTDEGLAYLMKRIKEIVEGQAAVNRCGGGVDFMEESMRPYPAVVNDEGMYAHARASAERLLGAGGVRVAPQLMGAEDFGFYAARMPSAFFTIGVGNATTSSARAAHTTHSPHFVIDEAALPVGAAVHAAVAIDYLSKHASSM
What is the function of this protein?
Hydrolyzes certain amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA).
What are the official names of this protein?
IAA-amino acid hydrolase ILR1-like 9.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
Protein: RLF2_ARATH
Sequence: MEARHMLVTILLLSFVFMNIMKVEAQKVIGYPAIGRDGARGCSPKDPSCPQQPEKPYKRGCEKITRCERDRRKQAHLRNPRKVLDVVAVMAKAKQLY
What is the function of this protein?
Cell signaling peptide that may regulate plant stress, growth, and development.  Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
What are the official names of this protein?
Protein RALF-like 2.
What is the protein family that this protein belongs to?
Belongs to the plant rapid alkalinization factor (RALF) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECR_PELPD
Sequence: MLTKPSALSRLVGELKKLPGVGERTALRLAFHLLKTPQNLTALSESLLEVKSRVRSCSICFAITEDDPCAICAGDRDTGTICVVENSQDLMALERSNAYHGTYHVLEGVISPLAGIGPSELRIAELLARIGRGGVDEVVIATNFTVEGEATALYLAKLLKPLGIRISRLAHGIPLGSDIEYVDAATVQWALQGRNQL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: NU1C_PROM3
Sequence: MSSGLDLELSFSQSLQGLGLSPQMAHLIWLPLPMLLVLTAAMVGVLVTVWLERKISAAVQQRIGPEYAGALGVLQPMADGLKLLVKEDVIPVRADGLLFTLGPVLVLVPVILSWLIVPFGQNLLISNVGIGIFLWISLSSIQPIGLLMSGYASNNKYSLLGGLRAAAQSISYEIPLALAVLAVVMMSNSLSTVDIVAQQNGAGLLSWNVWRQPVGFLIFWICALAECERLPFDLPEAEEELVAGYQTEYAGMKFALFYLGSYINLVLSSLLVAVLYLGGWGFPIPVEWLAGWLGQSVDAPLVQVITGSVGIVMTVLKAYLLVFLAILLRWTTPRVRIDQLLDLGWKFLLPIALGNLLITAALKLAFPVAFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PETL_NICGU
Sequence: MLTITSYFGFLLAALTITSALFIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: VF171_ASFK5
Sequence: MVVYDLLVSLSKESIDVLRFIETNLAAFNQQYIFFNIQRKNSIMTPLLITPQQEKISQIVEFLMDEYNKSNRRPGPPREQPMQAYPLLSYQQSSEEQPMMPYQQPPGDDDQPYEQIYHKKHASQQVNTELSDYYQHILALGDEDKGMDSMLKLPERAKRESDDEDDMFPIKKLTT
What are the official names of this protein?
Uncharacterized protein H171R, pH171R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H171R family.
What are the subcellular locations of this protein?
Virion.
Protein: RL22_MYCS2
Sequence: MSTVTEFPSATAKARYVRVSATKARRVIDLVRGKSVEEALDILRWAPQAASEPVAKVIASAAANAQNNEGLDPSTLVVATVYADEGPTAKRIRPRAQGRAFRIRKRTSHITVIVESRPPKQKGASAASARSRRAQGSKAAATKKSAETKEGSE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SPKA_SYNY3
Sequence: MTPDSRHRRLLANRYQLVELVGSGAMGQVYRAEDKLLGGVTVAVKFLSQALLNPRMKERFEREATISALLGEKSIHIVRVRDYGLDEKEIPFYVMEYLQGENISDVIKYRPLKVERFLKIARQICFGLDCAHKGIIYQGEACPVVHRDIKPSNVLLVEDPALGELVKILDFGIAKLVQAAEESKTQAFMGTLAYCSPEQMEGKELDSRSDIYSLGVMMYEMLTGEMPLFPDNSSFGGWYEAHHHTKPHPFSARYKIPASLEALVMNCLAKSPKGRPQSVDVIIRAIDAIEAEIKAPPISDTEKTQIAPHLLNTDMEATVVAQRGPGIVPETRLPLVSELCKQLEWPSDKPKQKIVFPYVLNAAEGKLASLWVMLNQEDILTRMSSIRYNQFLLMTSPHPMVLWITVLYHREYGPRWLPCYLDLKTRSGQSFAQMLGESGTYWLLFFALENPTRCQHMLTATVAPNQCKLLKEWAQTSQSMPGGKPQVTKRLLKQELDRLKPKIEAKLSQVKPSFNKEVSGL
What is the function of this protein?
Protein kinase that regulates cellular motility via phosphorylation of membrane proteins.
What are the official names of this protein?
Serine/threonine-protein kinase A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RPOA_HELAN
Sequence: MVREKITVSTRTLQWKCVESAADSKRLLYGRFILSPLMKGQADTIGIAMRRALLGEIEGTCITRAKSEKISHEYATIMGIQESVHEILMNLKEIVLRSNLYGTCEASICVRGPGYVTAQDIILPPYVEIVDNTQHIASLTEPIELVIGLQIEKNRGYLIKAPNTFQDGSYPIDPVFMPVRNANHSIHSYENGNKEILFLEIWTNGSLTPKEALHEASRNLIDLLIPFLHTKEENLSLEDNQHIVPLPPFTFYDKLAKLTKNKKKMALKSIFIDQSELPPRIYNCLKRSNIYTLLDLLNNSQEDLMKMEHFRIEDVKQILGILEKNFVIDLPKNKF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFTS_TOLAT
Sequence: MADITAAMVKELRERTAAGMMDCKKALTEANGDIELAIENMRKSGQAKAAKKAGRIAAEGIIIARSAGNVAVMLELNCETDFVAKDASFRALGEKVAEIALADKIADLEVLKNTDFGNGESVQVTLNNLIAKIGENMNLRRIVIAEGDNLATYIHGSRIGVITKLVGGDADLAKDLAMHVAANSPQFVKPEDVSAEVVAKEREIQVDIAINSGKPKEIAEKMVEGRMKKFTGDISLTGQPFVKDPSVIVADLLKQKGADVQDFIRFEVGEGIEKQETDFAAEVQAQIAAMKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_ACIBT
Sequence: MPNSQAKKGLFQFYPHNLIWLGLSVLAIVLDQWTKWIASTHLNYADPVPVLPFLNWTLLHNYGAAFSFLSDAGGWQRYFFTSLAGLVSILFVFWLLRMPKKMVVLPVAIALILGGALGNLIDRITLGYVVDFIHVYYQNHHFPAFNIADSAITLGTILLLIDTFFLEKQRPKNSDA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: C61C_CONCL
Sequence: MSGSGAMLLGLLILVAMATSLDTREICWHQSECDDPNEWCCIMGTSYGSCQPVCRP
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Cal6.41c, O3_cal6.1c.
What are the subcellular locations of this protein?
Secreted.
Protein: RL27_THENN
Sequence: MAHKKSGGVAKNGRDSLPKYLGVKVGDGQFVKAGNILVRQRGTRFHPGKNVGMGRDFTLFALKDGRVKFEQKNNKKYVSVYEE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RS181_MYCTO
Sequence: MAKSSKRRPAPEKPVKTRKCVFCAKKDQAIDYKDTALLRTYISERGKIRARRVTGNCVQHQRDIALAVKNAREVALLPFTSSVR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: AROQ_CLOBK
Sequence: MNNILVINGPNLNLLGKREPDIYGNITLENINQKIKLHFKNEDLKIHFFQSNEEGKIIDKIIESEKKYNAIVINPAAYSHYSIAILDAMRSINIPVVEVHLSNIYKREEYRKKSVTAEASLGVISGFGYYGYIMAIEFILNNLVREK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: BCHI_CHLTE
Sequence: MTQTANAAKKTTSTKASAAKEAKVKVTAEEKAVTEVKKPAAKKKSALAFPFTAIVGQEEMKLSLILNIIDPRIGGVLVMGHRGTGKSTTVRALAEVLPLIPRVKGDIYNRTVEQYIEMEAAGKGAPAIKPEDVETELIPVPVVDLPLGATEDRVCGTIDIEKALTSGVKAFEPGLLAQSNRGFLYIDEVNLLDDHLVDVLLDVAASGKNVVEREGISIRHPARFVLVGSGNPEEGELRPQLLDRFGLHARITTINDVAKRVQIVKLRREFDEDPEAFMKKVSREQQKLRKKIVAAQQLLPQVTMDDAVLTDIAKLCMNLGIDGHRGELTITRTAHAYAAWEGDKKVTMKHVREIAGLCLRHRLRKDPLETVDAGEKIDRELAKVLGEAEAAA
What is the function of this protein?
Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
What are the official names of this protein?
Magnesium-chelatase 38 kDa subunit, Mg-protoporphyrin IX chelatase.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family.
Protein: GLB75_CHITP
Sequence: MKFFAVLALCIVGAIASPLTADEASLVQSSWKAVSHNEVEILAAVFAAYPDIQNKFSQFAGKDLASIKDTGAFATHATRIVSFLSEVIALSGNTSNAAAVNSLVSKLGDDHKARGVSAAQFGEFRTALVAYLQANVSWGDNVAAAWNKALDNTFAIVVPRL
What are the official names of this protein?
Globin CTT-VIIB-5/CTT-VIIB-9.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MPKA_ASPFC
Sequence: MSDLQGRKVFKVFNQDFIVDERYNVTKELGQGAYGIVCAATNVHTGEGVAIKKVTNVFSKKILAKRALREIKLLQHFRGHRNITCLYDMDIPRPDNFNETYLYEELMECDLAAIIRSGQPLTDAHFQSFIYQILCGLKYIHSANVLHRDLKPGNLLVNADCELKICDFGLARGFSIDPEENAGYMTEYVATRWYRAPEIMLSFQSYTKAIDVWSVGCILAELLGGRPFFKGRDYVDQLNQILHYLGTPNEETLSRIGSPRAQEYVRNLPFMPKIPFQRLFPNANPDALDLLDRMLAFDPASRISVEEALEHPYLHIWHDASDEPTCPTTFDFHFEVVDDVQEMRKMIYDEVVRFRNLVRQQSQAQAAAAAQQQQQQIAQQTNVPIPDHQQGGWKQEEPKPQEVHAAGGHVNDLESSLQRGMDVQ
What is the function of this protein?
Mitogen-activated kinase (MAPK), part of the cell wall integrity (CWI) signaling pathway composed by three protein kinases bck1, mkk2 and mpkA and responsible for the maintaining of cell-wall integrity balance (PubMed:17981060, PubMed:19715768).  The CWI pathway regulates also the oxidative stress response, as well as the production of some secondary metabolites including gliotoxin, pyomelanin, pseurotin A, fumiquinazoline C or dihydroxynaphthalene (DHN)-melanin (PubMed:19715768, PubMed:21883519, PubMed:30914505, PubMed:33705521).  MpkA directly phosphorylates the fumiquinazoline C biosynthesis cluster nonribosomal peptide synthetase fmqC during conidiation (PubMed:33705521).  Mpka is also required for adaptation to iron starvation and regulates the expression of genes involved in siderophore biosynthesis in a hapX/sreA-independent manner (PubMed:21883519).
What are the official names of this protein?
Mitogen-activated protein kinase mpkA, MAPK mpkA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Note=Accumulates in the nucleus under iron depletion conditions.
Protein: PUR5_METMA
Sequence: MSEKHLTYADSGVDIKEEEKTVKTLIDKLSYVRKGIGAPLTGIGHYAGLLDFGEYALAMTTDGVGSKVLIANEMQRWNTVGIDCIAMNVNDLLAIGAEPVAFVDYLALEKHEEGFAEQIGEGLLKGAEISRMSIVGGETATLPDIIKGFDLAGTCLGYLKKEDIIEGGRVRVGDVIVGIPSTGVHSNGYTLVRKIIQESGYSYHDPCPYDSSKTIGDDLLEPTRIYIEVLDVLKACEVHGLAHITGSGLLKLRRVTKLGFDFYDPLEPQEIFKFLRKEGGVDDLEMYRTFNMGMGFLIILPEKDAEKAAEITGGKIVGKIVESGIRVKDLVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBK1_HUMAN
Sequence: MSVGCPEPEPPRSLTCCGPGTAPGPGAGVPLLTEDMQALTLRTLAASDVTKHYELVRELGKGTYGKVDLVVYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFIIKVFDVVFETEDCYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHGRQLVHRDIKPENVLLFDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTAPEVCQAGRADGLAVDTGVDVWAFGVLIFCVLTGNFPWEAASGADAFFEEFVRWQRGRLPGLPSQWRRFTEPALRMFQRLLALEPERRGPAKEVFRFLKHELTSELRRRPSHRARKPPGDRPPAAGPLRLEAPGPLKRTVLTESGSGSRPAPPAVGSVPLPVPVPVPVPVPVPVPEPGLAPQGPPGRTDGRADKSKGQVVLATAIEICV
What is the function of this protein?
May be involved in signal-transduction pathways related to the control of brain development.
What are the official names of this protein?
Serine/threonine-protein kinase SBK1, SH3-binding kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_PSEAB
Sequence: MRILADENIPVVDAFFADQGSIRRLPGRAIDRAALAEVDVLLVRSVTEVSRAALAGSPVRFVGTCTIGTDHLDLDYFAEAGIAWSSAPGCNARGVVDYVLGCLLAMAEVRGADLAERTYGVVGAGQVGGRLVEVLRGLGWKVLVCDPPRQAREPDGEFVSLERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQALRRLLEGGADLEVALDVWEGEPQADPELAAHCLIATPHIAGYSLEGKLRGTAQIYQAYCAWRGIAERVSLQDVLPETWLAGLQLNPGCDPAWALATLCRAVYDPRSDDAAFRRSLTGDSATRRAAFDALRKHYPPRREITGLRVATGGRVELQRVVRALGAQLV
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_VARPS
Sequence: MNELDSLVATARAAFAEAKTPAELENAKAQFLGKSGRITELMKGMAALSVDEKKSRGAAINVAKQAIEAALTERRQQLADEELSLQLRAEALDVSLPGRRRIPGGLHPVSRTLERIEEIFSSMGFDVADGPEIESDWHSFTSLNNPPNHPARSMQDTFYVDLNGDDGIPYNLRPHTSPMQVRYAHQHIKKYAAEFAAAAADATGTVKAPEIRVIAPGRTYRVDSDATHSPMFHQCEGLWLGENVSFKDLKVVFTDFCRTFFESDDLVLRFRPSFFPFTEPSAEIDIQFASGPLAGRWLEVAGSGQVHPNVVRNMGLDPERYIGFAFGMGPDRLTMLRYGVNDLRLFFDGDLRFLSQFQ
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM1H4_DEIAC
Sequence: FPYQGSSIMLESGKVNDYEVVYPRKVTALPKGAVQQKYEDTMQYEFKVNGEPVVLHLEKNKGLFSKDYSEIHYSPDGRRITTHPLVEGHCYYRGHIRNDADSTASISACNGLKGHFKIQGETYFIESLKLSDSEAHAVFKYENVEKEDEAHKMCGVTQNWESYEPIKKASQLIVSTEFQRYMEIVIVVDHSMYTKYKGDSDKIKAWVYEMINTISESYRYLYIDIIVSALEMWSEKDLINVETSAENTLKSFGEWRAKDLIHRISHDNAQLLTATDFDGPTIGLAYVASMCDPKRSVGVVQDHSSVNHLVAITLAHEIAHNLGVHHDEGSCSCGSGYTCIMSPVINSEVIKYFLDSK
What is the function of this protein?
Snake venom metalloproteinase that impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Snake venom metalloproteinase H4, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3_HALOH
Sequence: MGQKVHPHGLRVGVIKDWDAKWYADKNNYADLLQEDLKIRNHVKNKMYDAGISRIVIERVANRLKLDVYTARPGMVIGRGGSEVDALRKDIEQMTGKNVQINVVEVEDPELDAQLVAENIAAQLERRISFRRAMKQAMNRAMRMGAEGFKVQSSGRLGGAEMARTEGYSDGRVPLHTLRADIDYGFAEAYTTYGKIGVKVWINKGEVLPEVEDK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.