PharMolix/UniProtQA huggingface dataset:
Protein: LIGB_ECOLC
Sequence: MKVWMAILISILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQWDDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRKMVDKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSLISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSLGVFVWAWPDGPQLMSDRLKELATAGFTLTQTYTRAVKNADEVARVRNEWWKAELPFVTDGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLAPVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTPPENRFNSLTCYFASDVCQEQFISRLVWLGAKQVLGLDGIGEAGWRALHQTHRFEHIFSWLLLTPEQLQNTPGIAKSKSAQLWHQFNLARKQPFTRWVMAMGIPLTRAALNASDERSWSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: RS12_SHEB2
Sequence: MATVNQLVRKPRAPKVDKTNVPALNACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTIRGALDCAGVTSRRQSRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: Y577_ACTPJ
Sequence: MATQSKYQSKQFDALSGDLIAILEKHKAPVDLSLMALGNMVTNILLENVQTEAQRLALAEAFSNALKNSLKIK
What are the official names of this protein?
UPF0352 protein APJL_0577.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: TNF11_RAT
Sequence: MRRANRDYGKYLRGSEEMGSCPGVPHEGPLHPAPSAPAPAPPPAASRFMFLALLGLGLGQVVCSIALFLYFRAQMDPNRISEDSTRCFYRILRLRENTGLQDSTLESEDTEALPDSCRRMKQAFQGAVQRELQHIVGPQRFSGVPAMMEGSWLDVARRGKPEAQPFAHLTINAADIPSGSHKVSLSSWYHDRGWAKISNMTLSNGKLRVNQDGFYYLYANICFRHHETSGSVPADYLQLMVYVVKTSIKIPSSHNLMKGGSTKNWSGNSEFHFYSINVGGFFKLRAGEEISVQVSNPSLLDPDQDATYFGAFKVQDID
What is the function of this protein?
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK.  Osteoclast differentiation and activation factor.  Augments the ability of dendritic cells to stimulate naive T-cell proliferation.  May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response.  May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.  Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells, chief among which is induction of long lasting oscillations in the intracellular concentration of Ca (2+) resulting in the activation of NFATC1, which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts.  During osteoclast differentiation, in a TMEM64 and ATP2A2-dependent manner induces activation of CREB1 and mitochondrial ROS generation necessary for proper osteoclast generation.
What are the official names of this protein?
Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor ligand superfamily member 11, soluble form]: Secreted.
Protein: RL9_OCEIH
Sequence: MKVIFLKDVKGKAKKGDVKNVPDGYARNYLLKNNLAEEATSGNMKALEAKKQKADQLEQKEKEDAINLKDKLAEIAVELEAKSGDNGRLFGSITSKQISEALQKQFGHKIDKRKIELDEPIRALGYTTVPVKLHPEVSGSIKVHVAEK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: EFTU_NOVAD
Sequence: MAKAKFERNKPHCNIGTIGHVDHGKTTLTAAITKVLAEQGGAEFTDYANIDKAPEERERGITISTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVNAADGPMPQTREHILLARQVGVPALVVYMNKVDQVDDEEILELVELEVRELLSSYDFPGDDIPIVKGSALAALEGRDDNIGKDSINALMAAVDAYIPQPPRPTDKPFLMPVEDVFSISGRGTVVTGRIETGIIKVGEEVEIIGLKDTQKTTVTGVEMFRKLLDQGEAGDNIGALIRGIKREEVERGQVLAKPGSVTPHTEFSAEVYVLSKDEGGRHTPFFANYRPQFYFRTTDVTGEVVLPEGTEMVMPGDNVTLAVKLIAPIAMDEGLRFAIREGGRTVGSGVVSKITK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_AZOVD
Sequence: MMDINEIREYLPHRYPFLLVDRVVDLDVEGQRIRAYKNVSINEPFFNGHFPQHPIMPGVLIIEAMAQAAGILGFKMLDVKPADGTIYYFVGSDKMRFRQPVIPGDQLILEARFLSAKRSIWKFECQALVDDKQVCSGEIICAERKL
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C16B1_PICSI
Sequence: MVWKEAVSVLQKAQELKEPPLMFTVFLASFIGLAFFFYLISNHRTKAWRGIPPGTFGWPLIGETLEFLGCQRKGNPRDFFDSRTQKYGNVFTTSLVGHPTVVFCSPEGNRFLFSNENKLVVNSWPSSVGNLFRSSLITTVGDDAKRLRRILMTFLRPEALREFVGRVDSMTKRHLAEHWIGKDEVMALPLLKRYTFSLACDLFASINTKDDLDRLWLHFMVFVKGVMQIPIDLPGTRYNKTKHAANAIRQQLGSIINERKIALEAGNASPEQDLLSFLLSNVDEQGESLTDNEIQDNILLLLYAGHDTSSSTLTVLLKFLAENPHCYEEVLREQLNIAGSKEEGQLLEWEDLQRMKYSWRVAQEALRLFPAVQGSFRKAIKEFIYDGFTIPKGWKLHWTVNSTHQKSEYFSNPEKFDPSRFEGEGPPPYTFVPFGGGPRMCPGNEFARMEILIFLHNIVKNFNWNLVNPLEKVIVDPMPAPVNGLPIKLVPHD
What are the official names of this protein?
Cytochrome P450 716B1, Cytochrome P450 CYPA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: OPGD_ECOK1
Sequence: MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQRFDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLDAQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAGFRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFWFDTVKPGATTFTVYALLDSASITGAYKFTIHCEKNQVIMDVENHLYARKDIKQLGIAPMTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNPKGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVCFWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFPEGWAPGEHYPEKWARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSDSTDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KAD_MYCCT
Sequence: MNIMLLGAPGCGKGTQAEQLVNKLNFIQVSTGDLMRKEISLNTTLGLKCQEYMNAGKYVPDQIVNQIVNQFLQYNNDKLIFDGYPRTLEQAKSLEKMLDLYNKKIDYVFYIDVNEQILIKRITNRLVCPLCKASFNLETRKPKQEGLCDFDNTKLVKRSDDSLDKVKIRLQTYKEQTLPLIDYFKTNSKFIEIKADNLSAEQVFNQIKGELKI
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_NEOYE
Sequence: MVSTTKSTGSVTQIIGPVLDIAFPNGQLPKVFNALKVQSSEGTITCEVQQLLGDNKVRAVSMSSTEGLQRGVEVIDTGSPISVPVGTDTLGRIFNVLGEPVDNLGPVDSESTLPIHRPAPAFTKLETKPNIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESKVIDADNLKESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDINKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTTEGSITSIQAVYVPADDLTDPVPATTFAHLDATTVLSRNLAAKGIYPAVDPLDSTSTMLQPGIVGTEHYSTAQEVKSTLQRYKELQDIIAILGLDELSEEDRQTVSRARKIERFLSQPFFVAEVFTGSPGKYVSLEDAIKGFQMILKGNLDDLPEQAFYLVGDIDEAIQKADSMKD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GLYA_ALIFM
Sequence: MLKRDMNIADYDADLFAAIQEETVRQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGGCEYVDKVETLAIERACELFGAEYANVQPHSGSQANNAVYMALLNAGDTVLGMSLAHGGHLTHGSPVNFSGKLYNIIPYGIDENGQIDYEEMEALAVEHKPKMIIGGFSAYSQVCDWARMREIADKVGAYFFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILSNEGEDLYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEALEPEFKEYQARVVANAKAMVAEFLARGYNIVSGSTENHLFLVDLIDKDITGKEADAALGSANITVNKNSVPNDPRSPFVTSGIRIGSPSITRRGFTEEDAKNLAGWMCDILDNMGDESVIEATKAKVLEICKRLPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_SALAI
Sequence: MAAQVRVLRQRIRTAKSMKKITKAMELVATSRIAKAQDQVAASLPYARAITEVLTALASNARIDHPLLTPRERVRRAGVLLITSDRGLAGGYSTNAIKTAESLLARLRADGKEPALYVIGRKGVQFYRFRNRPIAASWTGFSEQPTFADAREVGQTLIKVFTAGVDDADGDPGPDGVFGVDELHIVSTEFKSLMTQRPVAKILGPMQVEDRPRAEGLLPAYEFEPEAEALLDALLPKYINTRIYAALVESAASESASRRRAMKSANDNAVEMIEKYTREMNSARQAGITQEISEIVGGANALAASGSEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: METK3_ACTCC
Sequence: METFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKGNIDYEKIVRDTCRNIGFVSDDVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKRPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKDGTCPWLRPDGKTQVTIEYYNENGAMVPIRVHTVLISTQHDETVTNDKIAADLKEHVIRPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASGLARRCIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKESFDFRPGMIAIHLDLKRGGNGRFLKTAAYGHFGRDDADFTWEVVKPLKWEKPQD
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 3, AdoMet synthase 3, Methionine adenosyltransferase 3, MAT 3.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XGPT_VIBC3
Sequence: MSKKFVITWDNMQHYCRELAQRQMPAEQWKGILGVSRGGLVPAAILARELGIRYVDTVCISSYDHDHQRDMTVLKAPEHDGEGFLIIDDLVDSGDTARKIREMYPKAKFVTVCAKPAGKDLVDEYVVDIPQDTWIEQPWDMVLSYVEPVNRKQK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HPRT_METVM
Sequence: MLLEETLKSCPIVKRGKYHYFIHPISDGVPLVEPKLLREVATRIIKIGNFEGVNKIVTAEAMGIPLVTTLSLYTDIPYVIMRKREYKLPGEVPVFQSTGYSKGQLYLNGIEKGDKVIIIDDVISTGGTMIAIINALERAGAEIKDIICVIERGDGKKIVEEKTGYKIKTLVKIDVVDGEVVIL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
What are the official names of this protein?
Hypoxanthine/guanine phosphoribosyltransferase, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCO2_ARATH
Sequence: MANDGNGDNNDDPLRQYLMNPRINPPPPSLLTLPENNDVTIPMPITPLELKNRLIFGSFVRSRKESSLPIDALSQNPSTSSSATTSFSDSTDLLLPLTEPNKPVRKSKPTINFHRSKTAPAMAAINNISHPNDPKTDQQSDSKTIVNQAVALLVVYLSLGVLIYWLNRDSYNVKQTHPVVDALYFCIVTMCTIGYGDITPDSVVTKLFSIFFVLVGFGFMDILLSGMVTYVLDLQENYMLETARNESLNLNDRDKVRSYIIDVKKGRMRIRLKVGLALGVVVLCLGFGVLIMHFVEKIGWLDSFYFSVMSVTTVGYGDRAFNTLAGRLLAAMWLLVSTLAVARAILFLAESRVDKRNRERAKKVLGESMSISQFLDADIDCNGCVSKAEFVIYKLKKMDKITEKDINPIGFQFDKLDRTNSGRITLLDLLESSTKDLPTATSI
What is the function of this protein?
Probable voltage-independent potassium-selective tonoplast ion channel.
What are the official names of this protein?
Two-pore potassium channel 2, AtTPK2, Calcium-activated outward-rectifying potassium channel 2, AtKCO2.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.7) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: EF1B_HALLT
Sequence: MGDVAAKIKVMPNSPDIDLDDLQDRLEESLPQGAKIRGFQRDDVAFGLVALLPTVIVPDGAGGTEAVEEAFNEVDGVESVAVENVGRL
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: LEPA_EXISA
Sequence: MNKQELENRQKKIRNFSIIAHIDHGKSTLADRILEKTGALTAREMKEQTLDAMDLERERGITIKLNAVKLNYTAKDGEEYILHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEIIPVINKIDLPSADVERVRQEIEDVIGLDASDAVPTSAKAGIGIEEILEQIVELVPPPTGDPSEPLQALIFDSYYDAYRGVVASIRIVNGSVKVGDKVQMMATGKTFEVTDLGVSTPKPISVKELNVGDVGTLSASIKTVGDVRVGDTITLAKNPATSQLPGYRKMNPMVYCGLYPIDAAKYNDLREALEKLQLSDAALEFEPETSQALGFGFRCGFLGMLHMEIIQERIEREFNIDLITTAPSVIYHVTTTSGEVIHVDNPSKMPEQQKVDSIEEPYVKAAVMTPNDYVGAIMELCQKKRGTFIDMQYIDTTRVKITYEIPLSEIVYDFFDQLKSSTKGYASLDYELIGYRQSRLVKMDILLNNEVVDALSFIVHRDFAYERGKVIVEKLKALIPRMQFEVPVQAAVGTKIVARSTIKALRKNVLAKCYGGDISRKRKLLEKQKEGKKRMKMVGSVEVPQEAFMSVLSMDEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SODM_HALMA
Sequence: MSEHSNPELPPLPYDYDALEPHISEQVLTWHHDTHHQGYVNGLESAEETLAENRDAGDFGSSAAAMGNVTHNGCGHYLHTLFWENMDPNGGGEPEGELLDRIEEDFGSYEGWKGEFEAAASAAGGWALLVYDPVAKQLRNVPVDKHDQGALWGSHPILALDVWEHSYYYDYGPARGDFIDAFFEVVDWDKAAEEYEKSVSHFE
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: SYY_GEOSE
Sequence: MDLLAELQWRGLVNQTTDEDGLRKLLNEERVTLYCGFDPTADSLHIGHLATILTMRRFQQAGHRPIALVGGATGLIGDPSGKKSERTLNAKETVEAWSARIKEQLGRFLDFEADGNPAKIKNNYDWIGPLDVITFLRDVGKHFSVNYMMAKESVQSRIETGISFTEFSYMMLQAYDFLRLYETEGCRLQIGGSDQWGNITAGLELIRKTKGEARAFGLTIPLVTKADGTKFGKTESGTIWLDKEKTSPYEFYQFWINTDDRDVIRYLKYFTFLSKEEIEALEQELREAPEKRAAQKTLAEEVTKLVHGEEALRQAIRISEALFSGDIANLTAAEIEQGFKDVPSFVHEGGDVPLVELLVSAGISPSKRQAREDIQNGAIYVNGERLQDVGAILTAEHRLEGRFTVIRRGKKKYYLIRYA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS, TyrTS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH11_PSEPK
Sequence: MRFFPTGRSMSLEQNYTEILSQIGEDVSREGLLDTPKRAAKAMKYLCRGYEQTLEEVTNNALFSSDNSEMVLVRDIELYSMCEHHMLPFIGKAHVAYLPKGKVLGLSKVARIVDMYARRLQIQENLSRQIAEAVQQVTGAAGVAVVVEAKHMCMMMRGVEKQNSTMITSVMLGEFRDNAATRSEFLSLIK
What are the official names of this protein?
GTP cyclohydrolase 1 1, GTP cyclohydrolase I 1, GTP-CH-I 1.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RECF_AZOVI
Sequence: MYGFRLCRPCRCGCKPATPPRCPSAVTVTRCVTSARVNQYISGPNGSGKRPAYWRRSTCSAWQLSSFRSQRLSPVIQHEQPACTVFGQVLWNDGRVRNLGVARNRLGELQIRIDGQNVRSAAQLAESLPLQLINPDSFRLLEGAPKVRRQFLDWGVFHVEQRFLPAWDRLQTALRQRNSWLRHGRIDPVSQAAWDRELCLRRSDSELLRAGRERCSARFLLLPFRAISNWGIPRRPQRADRRRRLARTMPRTCCRAVTRSWWSVRLKIAQGHLVDRARRECIYLVDDLPSELDEQHRRALCRLLEELHCQVFITCVDLEALREGWRTDTPVALFHVNRALITQPTIGSEGNDRKPTYDSSSIKS
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCY3_CAEEL
Sequence: MKNVFQLLIPLFFHLFSLVSLQNIPVSTGTTRPKLKVGIAAAQKTQSASIGWNVCGGAVPLAIERLKQAGYVTNFDFEYYVEYTECDLASTVRTGINFLKNLEVDVIIGPPCSEAIRTMATLATLYKKPVLGWGFVSQADLSDMTRFPYLITVLPTSQTLGYAASKLLELYKWDKVALLYYKSEVNHCGGVMNDVETTFNDPSTYSIQIVLKAEIDASDNVTTNAVISSVKTRARIILWCAQLGSEKRDYMIKISQLGLDTDEYVHVLISMRSIGFGVQTFVGKTTFKLSGLTPVWESFSNVTDGLENVAKRGATNVLVIDLNSEVSDKAYLDYMQRNILNVVKLPPLNCSTVDCVSSTATGMGAYARHLFDVVYLYGIALTRVNSTDSAVYDDMSKLIPQFVTSFNGMTGLVAINQNLSRMPLYQLYGLDEQYEQTSLMNLSFADGTTVATISLAYSNESSAVWHFWGGIRPLATPICGFLGNSCPLPFWEQYGILIFVGAGVFLIMITTNLICFLFMIKNRREEQARINSEWQIPFVKLRELERKSKGTSKRSLQSAPSTITGESKVSTGSEFCENYEVKMFEKDMVLTMKFQYMNLNKADMDKFVKLRKLDHENLNKFIGLSIDSSQFISVTKLCSRGSLLDILYKGNFSMDFFFMYCIIKDVAEGMSYLHKSFLRLHGNLRSATCLVNDSWQVKLAEFGFDQLLEEITPTKRRLLWAAPEVLRGSLTVSQMDPSADVFSFAIIASEILTRKEAWDLKERKEGYDEIIYRVKKGGSFPIRPDIITDVPDVNPTLIALVKDCWAEAPEDRPTAENICEQLRDLMPKTKSNLMDHVFNMLEEYTSTLEVEVEERTKELTLEKKKADLLLSRMLPKQVAERLKAGQTVEPEGFDSVTVFFSDVVKFTILASKCTPFQVVNLLNDLYSNFDTIIEEHGVYKVESIGDGYLCVSGLPTRNGFNHIKQIVDMSLKFMDYCKNFKIPHLPRERVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGKPSLIHLTSDAHLLLMKHFPHQYETNSRGEVIIKGKGVMETFWVLGRSGDIEPSISNRSTPPVTQERFTVRAPDTPEARSVSSHGSRPSSNHNNNNDPLYRQYKMDTLKI
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-3.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PRCD_CANLF
Sequence: MCTTLFLLSTLAMLWRRRFANRVQPEPSGADGAVVGSRSERDLQSSGRKEEPLK
What is the function of this protein?
Involved in vision.
What are the official names of this protein?
Photoreceptor disk component PRCD, Progressive rod-cone degeneration protein.
What is the protein family that this protein belongs to?
Belongs to the PRCD family.
What are the subcellular locations of this protein?
Cell projection, cilium, photoreceptor outer segment. Membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum. Golgi apparatus. Note=Localizes to photoreceptor disk membranes in the photoreceptor outer segment.
Protein: MT1_TETPI
Sequence: MDKVNNNCCCGENAKPCCTDPNSGCCCVSETNNCCKSDKKECCTGTGEGCKCTGCKCCQPAKSGCCCGDKAKACCTDPNSGCCCSSKTNKCCDSTNKTECKTCECCK
What is the function of this protein?
The metallothioneins are involved in the cellular sequestration of toxic metal ions.  Binds 12 cadmium ions per molecule.
What are the official names of this protein?
Metallothionein-1, MT-1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 7 family.
Protein: NAGZ_PSEAE
Sequence: MQGSLMLDIGGTWLTAEDRQILRHPEVGGLIIFARNIEHPAQVRELCAAIRAIRPDLLLAVDQEGGRVQRLRQGFVRLPAMRAIADNPNAEELAEHCGWLMATEVQAVGLDLSFAPVLDLDHQRSAVVGSRAFEGDPERAALLAGAFIRGMHAAGMAATGKHFPGHGWAEADSHVAIPEDARSLEEIRRSDLVPFARLAGQLDALMPAHVIYPQVDPQPAGFSRRWLQEILRGELKFDGVIFSDDLSMAGAHVVGDAASRIEAALAAGCDMGLVCNDRASAELALAALQRLKVTPPSRLQRMRGKGYANTDYRQQPRWLEALSALRAAQLID
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides (By similarity).  Contributes to intrinsic fosfomycin resistance in P. aeruginosa (PubMed:24819062).
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.