PharMolix/UniProtQA huggingface dataset:
Protein: RR15_ACOCL
Sequence: MVKNSFISLIPQEEKEENRGSVEFQVFSFTNKIRRLTSHLELHRKDYLSQRGLRKILGKRQRLLAYLSKKNRVRYNKLIGQLDIREPKTR
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MFS12_HORSE
Sequence: MVPGSPAAGAGPAPRALSLAARLSYAVGHFLNDLCASMWFTYLLLYLHSVRAYSSRGAGLLLLLGQVADGLCTPLVGYEADRAAGRCARCGPRKAWHLVGTVCVLLSFPFIFSPCLGCGAATPEWAALLYYGPFIVVFQFGWAATQIAHLSLIPELVTSDHEKVELTALRYAFTVVANITVFGAAWLLLRLQGSAREGPPDEAGDHLGVQDVPVFRTLSLCVVGVGAVFSLLFHLGTRERRRPPAQEPDERSPLLAPATARPLLLWKHWLREPSFYQVGLLYMSTRLIVNLSQTYIAMYLTYSLNLPKKFIATIPLVMYVSGFCSSFLMKPVNKCIGRNMTYFVGLLVILAFAAWVVLVDELGMAVYVAAVLLGGGCATILVTSLAMTADLIGPHTHSGAFVYGAMSFSDKVANGLAVMVIQSLHPCSLELCCRACVGFYHWVMVAVTGGVGVAATLSLCSLLVWPIRLRSWDPGAQP
What is the function of this protein?
Transporter that mediates the import of cysteine into melanosomes, thereby regulating skin/hair pigmentation.  In melanosomes, cysteine import is required both for normal levels of cystine, the oxidized dimer of cysteine, and provide cysteine for the production of the cysteinyldopas used in pheomelanin synthesis, thereby regulating skin/hair pigmentation.  Also catalyzes import of cysteine into lysosomes in non-pigmented cells.
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 12.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Melanosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein.
Protein: RETST_DANRE
Sequence: MWFAVVAIFLALVAFLYRYVVGSGPNPFAIDTREPLKPMVFDRKLKNKVLKQGFLASRVPEDLDAVVVGSGIGGLAIAVLLAKVGKKVLVLEQHDRAGGCCHTFKEQGFEFDVGIHYIGELSNHKPLRCIIDQMTNGQLQWDPLENPFDNVVIGPPENRRIYQIYSGRKRYMDELKKCFPGEEKAIDEYVRLCKEVGQGVWVMVLLKFLPTPIANFLVRTGLANRLTSFSRYASRSLTDVVNELTQNKDLRAVLSYIFGTYGKIPKEASFSMHSLIVNHYMNGAWYPKGGATEIAYHMIPIIEKAGGAVLVRAPVNRILLNDAKEAIGVSVLKGQEEVHVRAPIVISDAGIFNTYEYLLPKDVQTMPAIQKQLSMLQHGDSGLSIFIGLDGTKEELGLKADNYFIYPENNIDELLEDYRSGNREESAKKNPLIFVASPSAKDSTWPERTPGKSTLTVVSFANYEWFEEWKDDKVKNRSTDYKQLKELFINYILEAVTEIYPKIKDRIEYVDAGTPITNQHYIAAPRGEIYGADHGIPRFSAELNATIRAQTPIKNLYLTGQDLMLCGFAGALTGALTCGSVILNRNLHLEAFSLAKRVQNGNNKKKT
What is the function of this protein?
Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol.  In addition, saturates the 7-8 double bond of all-trans-retinol to produce all-trans-7,8-dihydroretinol.  Can also use vitamin A2 (all-trans-3,4-didehydroretinol) as a substrate, to produce all-trans-13,14-dihydro-3,4-didehydroretinol or all-trans-7,8-dihydro-3,4-didehydroretinol.  May play a role in vitamin A metabolism.
What are the official names of this protein?
All-trans-retinol 13,14-reductase, All-trans-13,14-dihydroretinol saturase A, RetSat A, All-trans-retinol 7,8-reductase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: TRI55_HUMAN
Sequence: MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPTGSEQTTESETPVPAAAETADPLFYPSWYKGQTRKATTNPPCTPGSEGLGQIGPPGSEDSNVRKAEVAAAAASERAAVSGKETSAPAATSQIGFEAPPLQGQAAAPASGSGADSEPARHIFSFSWLNSLNE
What is the function of this protein?
May regulate gene expression and protein turnover in muscle cells.
What are the official names of this protein?
Tripartite motif-containing protein 55, Muscle-specific RING finger protein 2, MuRF-2, MuRF2, RING finger protein 29.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Nuclear under atrophic conditions and upon mechanical signals. Localizes to the sarcomeric M-band in cardiomyocytes. Colocalizes in part with microtubules (By similarity).
Protein: NADK_PORGI
Sequence: MKKIAIFGSRHKSEQGASIKALILKLEEAGTPLYIERKFLSFLKQDLDFHPAICGVIDTLPEHIDYVICMGGDGTFLRTAHQIGVSQIPVLGVNTGRLGFLTDVDCHEASELITRLLDGDFTIETRSLLEVTEDNGSSPSYALNEAAILKRETGSMIRVNACLNDDYLAAYDADGLVVATPSGSTAYSLSGNGPIIMPACRNFVLTPIAPHSLNMRPLVVPDDTVIRLEVDSRSRNYLLVLDGRTRTLPCDTSILLKRAPHTLRMIRLRPHSFAETLRRKLMWGAAVR
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSF_BPB03
Sequence: MYSFTAYANSVIVAFHLLKFSSSENNIEISYADEDTIPEYVSIRDLNAGDKTTVELYPLVAWKVIAQEDISTGDRVSVGKNGQVKKTTDMRTTFGYAVSPAKAGQLVTVAISTVFDTIITPDDLGDVDDDVKAFLKSNTTDENKSNLRELLVADADVKALLSGSTTDANKAKLRDLLFSNLDVKAFLSGSTSEDNKVNLRNLLVSNPAILAFLNANPDTDTQTTLRTMIGAGTPYTLPAATTTTLGGVKRMPAIANSTATDVATLVKDFNNLLAALRTAGHSL
What is the function of this protein?
Protein that forms the 55 capsid fibers.  These fibers are not always present and may have been lost in some lab strains.  They may enhance the attachment of the virions onto the host cell wall.
What are the official names of this protein?
Capsid fiber protein, Gene product 8.5, gp8.5, Head fiber protein, Protein p8.5.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus major capsid fiber protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RL17_PROM1
Sequence: MRHQRRIPQLSLPADQRKALLRGLTTQLIREGRVTTTKARAKALRNETERMITLAKDGSLASRRRAIGYVYDKQLVHALFEKAQERYGDREGGYTRIVRTTPRRGDNSEMAIVELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DDRGK_CAEEL
Sequence: MDPLLLGSVGVLVLAVTLIIWRLLKLQWDEKAARQRTDMLLAMNEGAGGSDERRGANVAGGMRRNARRRVNRDEQEDGFVNHMMNDGEDVEDLDGGAEQFEYDEDGKKIGKRKAAKLQAKEEKRQMREYEVREREERKRREEEREKKRDEERAKEEADEKAEEERLRKEREEKERKEHEEYLAMKASFAIEEEGTDAIEGEEAENLIRDFVDYVKTNKVVNIDELSSHFGLKSEDAVNRLQHFIEEGLVQGVMDDRGKFIYISDEEFAAVAKFINQRGRVSIHEIAEQSNRLIRLETPSAAE
What are the official names of this protein?
DDRGK domain-containing protein 1, Ufm-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDRGK1 family.
Protein: ATPE_ALBFT
Sequence: MNTIHVDVVSAEESIFSGEARFVALPGEVGELGIYPRHTPLISRIKAGSVRIEKADGSEEFVFVAGGLLEVQPNCVTVLSDTAIRGKDLDEEKANAAKLAAEEAMKNAKTDIDLARATSELAVMAAQIAALRKYRQKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MTND_SYNPW
Sequence: MSELSIYSEQGGEPVFSTLDSARIQHELSLRGIAFDRCASKAEIALDADQADILSTYAEEIHRIQALGDYPTVDAIRMKPDHPDRQALRQKFLSEHTHAEDEVRLFVEGRGLFCLHIKSEVLQVTCETNDWISVPAGTRHWFDMGEKPYFCAIRFFNNPNGWVANFTNDPIAERFSKLRD
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: RNPH_XANC5
Sequence: MTFSRPSGRTADQLRPVRIERAFTRHAEGSVLVSFGDTRVLCTASVENRVPGFLRGKGEGWVTAEYGMLPRSTHTRSDREAARGKQGGRTLEIQRLIGRALRACVDRNALGERTITLDCDVLQADGGTRTAAITGAYVALADAVNLLIKRGDIKKHPLIGAVAAVSVGIYRGEPVLDLDYPEDSDCDTDMNVVMNDGGGFIELQGTAEGHAFRRDELNALLALAEKGMGELFALQRAALAG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RL17_CLOBH
Sequence: MAGYRKLGRPTDQRKAMLRNLVTSFLKHGKIETTETRAKETRSIAEKMITLAKRGDLHARRQVLSFVTEETVVQRLFEEIAPKYAERNGGYTRIYKVGPRRGDGAEVVILELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ZN722_HUMAN
Sequence: MAERPGSPGSREMRLLTFRDIAIEFSLEEWQCLDCAQQNLYRDVMLENYRNLVSLGIADSKPDLITCLEQNKEAWNIKRNEMVAKHPVTCSHFTQDLHPEQGIKHSLQKVIPRTYGKCGHENLQFKKCCKSVGECEVHKGGYNEVKQCLSNTQNKIFQTHKCVIVFGKFSNCNRHETRYTGKKHFKCKKYGKSFCMPSHLNQHQIIHTKEKSYKCEECGKSFKRSSNCTTHKRIHTGEKPYRCEECGKAFRWPSNLTRHKRIHTGEKPYTCEECGQAFRRSSTLTNHKRIHTGERPYKCEECGKAFSVSSTLNDHKRIHTGEKPYTCEECGRAFNCSSTLKTHKRIHTGEKPYKCEECDKAFKRHSSLAKHKIIHTGEKPYKSK
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 722.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BP48_BPT4
Sequence: MAIVKEITADLIKKSGEKISAGQSTKSEVGTKTYTAQFPTGRASGNDTTEDFQVTDLYKNGLLFTAYNMSSRDSGSLRSMRSNYSSSSSSILRTARNTISSTVSKLSNGLISNNNSGTISKSPIANILLPRSKSDVDTSSHRFNDVQESLISRGGGTATGVLSNIASTAVFGALESITQGIMADNNEQIYTTARSMYGGAENRTKVFTWDLTPRSTEDLMAIINIYQYFNYFSYGETGKSQYAAEIKGYLDDWYRSTLIEPLSPEDAAKNKTLFEKMTSSLTNVLVVSNPTVWMVKNFGATSKFDGKTEIFGPCQIQSIRFDKTPNGNFNGLAIAPNLPSTFTLEITMREIITLNRASLYAGTF
What is the function of this protein?
Baseplate protein that forms, together with gp54, the baseplate-tail tube junction.  The tail tube first 2 annuli are formed by gp48 and gp54, which are in continuation of the spike complex.  Involved in the tail assembly.  Morphogenesis of the baseplate is completed by association of gp48 and gp54, which bind the upper part of the baseplate dome to form the platform for polymerization of the tail tube.
What are the official names of this protein?
Baseplate tail-tube junction protein gp48, Baseplate-tube cap, Gene product 48, gp48.
What are the subcellular locations of this protein?
Virion. Note=Present in 6 copies in the baseplate.
Protein: SYE2_METCA
Sequence: MTHRTRFAPSPTGHLHIGGARTALFSWLYARKHGGTFILRIEDTDLERSTVESVNAILEGMTWLGLEYDEGPFYQTHRFDRYREVMEQLLEEGHAYRCYCTKEELDELRAGQMERKEKPRYDGRCRHRSEPRPGVLPVIRFRNPTEGEVAWDDLVRGRIAFQNSELDDLIIARSDGTPTYNFTVVVDDLDMKISHVIRGDDHVNNTPRQINILKALGVEPPRYGHVPMILGADGARLSKRHGAVSVMQYRDEGYLPEALLNYLVRLGWSHGDQEIFSVDEMIEYFDANAINHSAATFNPDKLLWLNHHYLMHSDPAHVAHHLRWHLGRLDIDPTEGPDPVDVVVAQRERCKTLVEMAQASRFFYRDFDDYDPKSAQKYLTAASVPALESLRRHLAVVRSWEKEFLHAVLVATGEEMGLKLGAVAQPLRVAVAGTAVSPPMDVTLHLLGQLRTLNRIDRALQYIEAKKD
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPFA_MYCTU
Sequence: MSGRHRKPTTSNVSVAKIAFTGAVLGGGGIAMAAQATAATDGEWDQVARCESGGNWSINTGNGYLGGLQFTQSTWAAHGGGEFAPSAQLASREQQIAVGERVLATQGRGAWPVCGRGLSNATPREVLPASAAMDAPLDAAAVNGEPAPLAPPPADPAPPVELAANDLPAPLGEPLPAAPADPAPPADLAPPAPADVAPPVELAVNDLPAPLGEPLPAAPADPAPPADLAPPAPADLAPPAPADLAPPAPADLAPPVELAVNDLPAPLGEPLPAAPAELAPPADLAPASADLAPPAPADLAPPAPAELAPPAPADLAPPAAVNEQTAPGDQPATAPGGPVGLATDLELPEPDPQPADAPPPGDVTEAPAETPQVSNIAYTKKLWQAIRAQDVCGNDALDSLAQPYVIG
What is the function of this protein?
Factor that stimulates resuscitation of dormant cells.  Has peptidoglycan (PG) hydrolytic activity.  Active in the pM concentration range.  Has little to no effect on actively-growing cells.  PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity.  Stimulates growth of stationary phase M. bovis (a slow-growing Mycobacterium), reduces the lag phase of diluted fast-growers M. smegmatis and Micrococcus luteus.
What are the official names of this protein?
Resuscitation-promoting factor RpfA.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. Rpf subfamily.
Protein: RS13_LEIXX
Sequence: MARLAGVDIPREKRVEVALTYIYGVGRTRALQTLRETEISGEIRVKDLTDEQLVSLRDYIEGNFKVEGDLRREVAADIRRKVEIGSYEGIRHRKGLPVRGQRTKTNARTRKGPKRTVAGKKKAR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ZN707_HUMAN
Sequence: MDMAQEPVTFRDVAIYFSREEWACLEPSQRALYRDVMLDNFSSVAALGFCSPRPDLVSRLEQWEEPWVEDRERPEFQAVQRGPRPGARKSADPKRPCDHPAWAHKKTHVRRERAREGSSFRKGFRLDTDDGQLPRAAPERTDAKPTAFPCQVLTQRCGRRPGRRERRKQRAVELSFICGTCGKALSCHSRLLAHQTVHTGTKAFECPECGQTFRWASNLQRHQKNHTREKPFCCEACGQAFSLKDRLAQHRKVHTEHRPYSCGDCGKAFKQKSNLLRHQLVHTGERPFYCADCGKAFRTKENLSHHQRVHSGEKPYTCAECGKSFRWPKGFSIHRRLHLTKRFYECGHCGKGFRHLGFFTRHQRTHRHGEV
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 707.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YLCJ_ECOLI
Sequence: MSLVLCFLLMSLFFMYSFVLSRLWRKKIAIRLLLYIQDNVTLIVFLNKK
What are the official names of this protein?
Protein YlcJ.
Protein: C75A4_GENTR
Sequence: MSPIYTTLTLHLATALFLFFHVQKLVHYLHGKATGHRCRRLPPGPTGWPILGALPLLGNMPHVTFANMAKKYGSVMYLKVGSHGLAIASTPDAAKAFLKTLDLNFSNRPPNAGATHLAYNAQDMVFAHYGPKWKLLRKLSNLHMLGGKALENWADVRKTELGYMLKAMFESSQNNEPVMISEMLTYAMANMLSQVILSRRVFNKKGAKSNEFKDMVVELMTSAGYFNIGDFIPSIGWMDLQGIEGGMKRLHKKFDVLLTRLLDDHKRTSQERKQKPDFLDFVIANGDNSDGERLNTDNIKALLLNLFTAGTDTSSSIIEWALAELLKNRTLLTRAQDEMDRVIGRDRRLLESDIPNLPYLQAICKETFRKHPSTPLNLPRNCIRGHVDVNGYYIPKGTRLNVNIWAIGRDPSVWGDNPNEFDPERFLYGRNAKIDPRGNHFELIPFGAGRRICAGTRMGILLVEYILGTLVHSFDWKLGFSEDELNMDETFGLALQKAVPLAAMVIPRLPLHVYAP
What is the function of this protein?
Catalyzes the 3'5'-hydroxylation of naringenin and eriodictyol to form 5,7,3,'4',5'-pentahydroxyflavanone and 3',5'-hydroxylation of dihydrokaempferol and dihydroquercetin to form dihydromyricetin.
What are the official names of this protein?
Flavonoid 3',5'-hydroxylase, F3'5'H, Cytochrome P450 75A4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: NTRK3_PANTR
Sequence: MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINTDGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTISGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLFVMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG
What is the function of this protein?
Receptor tyrosine kinase involved in nervous system and probably heart development.  Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
What are the official names of this protein?
NT-3 growth factor receptor, Neurotrophic tyrosine kinase receptor type 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y920_CARHZ
Sequence: MKITFLGHAAFLVEEEGLKFLFDPFLTGNPQAKIRPDEITADYILVSHGHGDHLGDTVAIAQRSGATVIGVFELCNFLSRQNVKTHPMHIGGRYNFGQFTVKLTPAWHGSSFGEGPVEYLGNPCGFLLSVGGKTLYHTGDTGLFYDMKLLAEIDPVDILLVPIGGNFTMDVKDALKALELVKPKYAIPMHYNTWPVIAADVGEFQDKGRALGVAIKVLNPGEMVVL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase CHY_0920.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: MSRA_PECAS
Sequence: MNSIDKTQRITQSDALPGRSTPMPVARLHVVHEHSMTHVPDHMSVAIFAMGCFWGAERLFWQQPGIYSTAAGYIGGYTPNPTYREVCSGQTDHAEAVRVVFDPATISYSQLLQLFWENHDPAQGMRQGGDIGSQYRSAIYTLTPEQEQAAQASLQRFQQAMRENSDGRAISTEIEPAGPFYYAEEDHQQYLHKNPNGYCGLGGIGVCLPPPR
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: XPP2_MOUSE
Sequence: MAQAYWQCYPWLVLLCACAWSYPEPKYLGREDVRNCSTSPERLPVTAVNTTMRLAALRQQMETWNLSAYIIPDTDAHMSEYIGKPDKRREWISGFTGSAGTAVVTMGKAAVWTDSRYWTQAERQMDCNWELHKEVSISSIVAWILAEVPDGQNVGFDPFLFSVDSWKNYDQGFQDSSRHLLSVTTNLVDVAWGSERPPVPSQPIYALPKEFTGSTWQEKVSAVRSYMEHHAKTPTGVLLSALDETAWLFNLRSSDIPYNPFFYSYALLTNSSIRLFVNKSRFSLETLQYLNTNCTLPMCVQLEDYSQVRDSVKAYASGDVKILIGVSYTTYGVYEVIPKEKLVTDTYSPVMLIKAVKNSKEQALLKSSHVRDAVAVIQYLVWLEKNVPKGTVDEFSGAEYIDELRRNENFSSGPSFETISASGLNAALAHYSPTKELHRKLSSDEMYLVDSGGQYWDGTTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVIEAFARRALWEVGLNYGHGTGHGIGNFLCVHEWPVGFQYNNIAMAKGMFTSIEPGYYHDGEFGIRLEDVALVVEAKTKYPGDYLTFELVSFVPYDRNLIDVRLLSPEQLQYLNRYYQTIRENVGPELQRRQLLEEFAWLEQHTEPLSARAPHIISWTSLWVASALAILSWSS
What is the function of this protein?
Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.  May play a role in the metabolism of the vasodilator bradykinin.
What are the official names of this protein?
Xaa-Pro aminopeptidase 2, Membrane-bound aminopeptidase P, Membrane-bound APP, mAPP, X-prolyl aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: DUT_PORG3
Sequence: MKIKIINRSHHPLPAYATSASAGMDLRASIEEPITLLPLERRLIPTGLFIELPVGYEAQIRPRSGLALRHGITLVNSPGTIDADYRGEIGIIMINLSNTPFTIADGERICQLVIARHEQAEWVLTDELADTERGAGGFGHTGKE
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RPOC1_MARPO
Sequence: MTYQKKHQHLRIELASPEQIRNWAERVLPNGEIVGQVTKPYTLHYKTHKPEKDGLFCEKIFGPIKSGICACGKYQGIEKKKENIKFCEQCGVEFIESRIRRYRMGYIKLACSVTHVWYLKRLPSYIANLLAKPLKELESLVYCDLFLARPITKKPTLLKLQGLFKYEDQSWKDIFPRFFSPRGFEVFQNREIATGGDAIQKQLTNLNLQNVINLAHLEWKEFAEQKSTGNEWEDRKIQRRKDLLVRRIKLAKHFIQTNIKPEWMVLSLLPVLPPELRPMIELGEGELITSDLNELYRRVIYRNNTLLDFLARSGSTPGGLVVCQKRLVQEAVDALIDNGIRGQPMKDSHNRPYKSFSDLIEGKEGRFRENLLGKRVDYSGRSVIVVGPFLPLHQCGLPREMAIELFQAFVIRGLIGRNFAPNLRAAKTMIQNKEPIIWKVLQEVMQGHPILLNRAPTLHRLGIQAFQPILVNGRAIHLHPLVCGGFNADFDGDQMAVHIPLSLEAQAEARLLMLSHKNLLSPATGEPISVPSQDMLLGLYILTIENNQGIYGNKYNPSKKYDSKKKFSQIPYFSSYDNVFRALQQKQIYLHSSLWLRWQINLRIITLLNQEGPIEIQYKSFGNSFQIYEHYQLRKNKNQEIISTYICTTAGRILFNQQIEEAIQGTYKASLKQKTFVQKIEKNG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VATA_STRPN
Sequence: MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRRDQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDFLVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVVSIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVIDAFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPELIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVSPPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKEKTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFDSVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSEDRLDEIKIISNEITHQIHLILETGGL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: VU84_HHV6Z
Sequence: MKDRGNKNTSKTRPTVKSRRTRKTTKPSTERKKNVTTKTTIRNNRLQNNLSSQTVQTDKPVDSATARAFPQHTSPDIKFNKEKYRNNAIYAHSKLRKISNAVFHQDKEINRFSAFTDKPLADLSFNMPVKTSTTQKKEIVKSTECQRQDPNAVNAFKIFQSYETSPPYSPCSPKNFMSEIYRLFRCYNASIVQIQVYSRNKILINAMQEKLMSIGNMVINVGEQIISESVHHEPVVAIAINQFFRGTVPHTDALRKNAVAPIPVNASKKKLVGICSLMINAPTEKDLLCAAHVCINFAICHPNEITLNIAKLTQPMLLREHITIYNSFNKYIYWDDYGKLLN
What are the official names of this protein?
Protein U84.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U84 family.