PharMolix/UniProtQA huggingface dataset:
Protein: PUR7_ECOHS
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RL14_GEODF
Sequence: MIQMQTILDVADNSGAKKLFCIKVLGGSKRKYAGIGDIIVASVKEAIPNSKVKKGDVVKAVVVRTAKEIGRPDGSYIRFDGNSGVVINNQKEPVGTRIFGPVARELRAKKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GAG_HV2CA
Sequence: MGARNSVLRGKKADELEKVRLRPGGKKKYKLKHIVWAANELDRFGLAESLLESKEGCQRILKVLDPLVPTGSENLKSLFNTVCVIWCIHAEEKVKDTEEAKRIALRHLAAETGTAEKMPDTSRPTAPPSGKGGNYPVQSIGGNYTHVPLSPRTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIREIINEEAADWDANHPIPGPLPAGQLRDPRGSDIAGTTSTVEEQIQWMFRAQNPVPVGNIYRRWIQIGLQKCVRMYNPTNILDIKQGPKESFQSYVDRFYKSLRAEQTDPAVKNWMTQTLLVQNANPDCKLVLKGLGMNPTLEEMLTACQGVGGPGQKARLMAEALKEAMGPPPIPFAAAQQRRTIKCWNCGKEGHSARQCRAPRRQGCWKCGKPGHIMTNCPDRQAGFLGIGPWGKKPRNFPVAQVPQGLTPTAPPLDPAVDLLEKYMQQGKRQREQRQRPYKEVTEDLLHLEQGEAPCRETTEDLLHLNSLFGKDQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: DBP9_NEUCR
Sequence: MAKRKLNETDEPSVVTEPQTQKKTKKSSTEKKEKKEKKSKSQSVKPQEEKPEATQQQAQQQTEEEQELEQQLKDEQKQQDEKDEKKQSEKDDADLTFSDLGLDPRLVQAVAKQSFEKPTLVQRKAIPLALAGQDVLCKAKTGSGKTAAYVLPVLSGILKRKATDPTPFTSALILVPTRELADQVHKAIDAFSAFCTKDIQSAKLTDNVSDAVLRSLLANAPDVIVSTPARAWHNIESGALSVAKLQYLVLDEADLVLSYGYDEDMENIARSLPKGGVQTTMMSATLVSDELDTLKGFFCRNPTMLDLKEEFSNEDEKLTQFYVKCGEDDKWLISYLIFKLQLIKGPCLVFVADIDRAYRLKLFFEQFSIRSCVLNSELPINTRIKIIEEFNRGIYDIIIASDERSEVFLEDEKTEEKKEEQGEKKEGDEKKNGKGKKKKGRRDQEYGVSRGIDFKNVAAVINFDMPTSSSSYIHRIGRTARAGRAGIALSMVVPHDLFGKHKPTSIKQCEKDEKVLAKVMRQQAKLNRKLEPYNFNKDQMEAFRYRMNDALRAVTKVAIREARTRELRQELLRSETLKRYFEENPHELSHLRHDGELGTKMRQQAHLKHVPDYLLPQDGKNALTETQIGFVPFKKQGDDKKTRGKKGAKGGKGGHGKYKKGPGGRKNVLKTFRVRK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp-9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL32_PARMW
Sequence: MAVPKKKTSKAKRNQRSATWKGKAAVAAQRAMSIGKSVLSGRAQGFVYPVREADDEES
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MX1_BOVIN
Sequence: MVHSDLGIEELDSPESSLNGSEDMESKSNLYSQYEEKVRPCIDLIDSLRSLGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLRLKKLGNEDEWKGKVSFLDKEIEIPDASQVEKEISEAQIAIAGEGTGISHELISLEVSSPHVPDLTLIDLPGITRVAVGNQPPDIEYQIKSLIRKYILRQETINLVVVPANVDIATTEALRMAQEVDPQGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQDIKHRMSLDKALQRERIFFEDHAHFRDLLEEGKATIPCLAERLTSELIMHICKTLPLLENQIKETHQRITEELQKYGKDIPEEESEKMFCLIEKIDTFNKEIISTIEGEEFVEQYDSRLFTKVRAEFSKWSAVVEKNFEKGYEAIRKEIKQFENRYRGRELPGFVNYKTFETIIKKQVRVLEEPAVDMLHTVTDIIRNTFTDVSGKHFNEFFNLHRTAKSKIEDIRLEQENEAEKSIRLHFQMEQLVYCQDQVYRRALQQVREKEAEEEKNKKSNHYFQSQVSEPSTDEIFQHLTAYQQEVSTRISGHIPLIIQFFVLRTYGEQLKKSMLQLLQDKDQYDWLLKERTDTRDKRKFLKERLERLTRARQRLAKFPG
What is the function of this protein?
Interferon-induced dynamin-like GTPase with antiviral activity against rabies virus (RABV), vesicular stomatitis virus (VSV) and murine pneumonia virus (MPV).  Isoform 1 but not isoform 2 shows antiviral activity against vesicular stomatitis virus (VSV).
What are the official names of this protein?
Interferon-induced GTP-binding protein Mx1, Myxoma resistance protein 1, Myxovirus resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Note=Binds preferentially to negatively charged phospholipids. Colocalizes with CCHFV protein N in the perinuclear region. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.
Protein: Y2389_STRAW
Sequence: MGEEYEVEIGPVAHGGHCIARTSEGQVLFVRHALPGERVLARVTEGEEGARYLRADAVEILDASKDRVEAPCPYAGPGRCGGCDWQHAKPGAQRRLKGEVIAEQLQRLAGLTPEEAGWDGTVMPAEGDKLPAGEVPAWRTRVQYAVDADGNAGLRRHRSHEVEPIEHCMIAAPGVSELGIEERDWSGMESVDAIAATGSQDRMVILEPRPGARLPLVELDKPVSVMRVEEKDGGIHRVHGRAFVRERADGRTYRVGSGGFWQVHPMAADTLVKAVMQGLLPRKGDMALDLYCGVGLFAGALADRLGDKGAVLGIESGKRAVEDARHNLAAFERVRIEQGKVEAVLPRTGITEVDLIVLDPPRAGAGKKTVEQLVSLGARKIAYVACDPAALARDLGYFRDGGYKVRTLRAFDLFPMTHHVECVAILEPAAKGL
What are the official names of this protein?
Uncharacterized RNA methyltransferase SAV_2389.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: PAT_CITK8
Sequence: MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIDYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFSNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGSLSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALSECKKTGDDVAAVILEPIQGEGGVILPPQGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPVGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFLQLAREYPDLVQDARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNSKTIRIEPPLTLTIEQCEQVLKATRKALAALRVSVEET
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: RS21_KLEP3
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: INLH_LISMO
Sequence: MKKRWNSVFKLVLMVTAILGLSLYVTTSQGVEVRAESITQPTAINVIFPDPALANAIKIAAGKSNVTDTVTQADLDGITTLSAFGTGVTTIEGVQYLNNLIGLELKDNQITDLTPLKNLTKITELELSGNPLKNVSAIAGLQSIKTLDLTSTQITDVTPLAGLSNLQVLYLDLNQITNISPLAGLTNLQYLSIGNAQVSDLTPLANLSKLTTLKADDNKISDISPLASLPNLIEVHLKNNQISDVSPLANTSNLFIVTLTNQTITNQPVFYQNNLVVPNVVKGPSGAPIAPATISDNGTYASPNLTWNLTSFINNVSYTFNQSVTFKNTTVPFSGTVTQPLTEAYTAVFDVDGKQTSVTVGANELIKEPTAPTKEGYTFTGWYDAKTGGTKWDFATDKMPAEDITLYAQFTINSYTATFDIDGKLTTQKVTYQSLLEEPVAPTKDGYTFTGWYDAKTGGTKWDFATGKMPAGNITLYAQFTKNDNPNPDDPTTNTPTGNGDGTSNPSNSGGNTTLPTAGDENTMLPIFIGVFLLGTATLILRKTIKVK
What is the function of this protein?
Contributes to systemic listeriosis in mice by decreasing host IL-6 cytokine production and thus evasion of the host immune response.  Does not contribute to invasion of the host intestinal tissue.
What are the official names of this protein?
Internalin H.
What is the protein family that this protein belongs to?
Belongs to the internalin family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Secreted. Note=In the absence of SrtA in exponential phase some protein is still anchored to the cell wall while protein levels are the same in the srtA mutant; in stationary phase much less protein accumulates (PubMed:22837151). During exponential growth detected on the cell surface as a series of dots in a helical pattern, it is excluded from the septum (PubMed:21725001). The helical pattern of InlA does not overlap with that of InlH, InlJ or Hbp2 (SvpA) (PubMed:21725001). In stationary phase colocalizes with InlA at cell poles and at the septum, the location shift requires SigB (PubMed:21725001).
Protein: RS3A_TAESO
Sequence: MAPTKQQSQKGVKKGGKKKTTDPFSKKEWYELRAPSMFSNRTCARTLITRTQGTKIASEGLKGRVIQLSLGDLSDKTQDIFRKFKLQVEDVQGRHCLTNFHGMDLTRDKLCGMVLKWQSTIEAHVDVKTTDGYTLRFFVIAFTKKQEDQKSHAYAQTTRIKKLRAKIVEVVQREVARCDLKSVVQKLIPDSIGQDAMNEASSIFPLSGALVRKVKVLKKPKLDLGRILELHSEGKADEFGEGVPRPDHYEPPVVNAV
What are the official names of this protein?
40S ribosomal protein S3a, Ts6 protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSHL_CHLT2
Sequence: MKGQKYYSDYHVWIEPIHSRIVKLGLSSQMREHLGNILHIDLPSVGSFIKEGEELCILESSKSAIEVLSPVSGEVLEVNTALEDDILPVNNATESEGWFVVLQLTEDFRSESFSLEP
What are the official names of this protein?
Glycine cleavage system H-like protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: MSRQ_PSEAE
Sequence: MRYWYLRLAVFLGALAVPAWWLYQAWIFALGPDPGKTLVDRLGLGALVLLLLTLAMTPLQKLSGWPGWIAVRRQLGLWCFTYVLLHLSAYYVFILGLDWGQLGIELSKRPYIIVGMLGFVCLFLLAITSNRFAMRKLGSRWKKLHRLVYLILGLGLLHMLWVVRADLEEWTLYAVVGASLMLLRLPSIARRLPRLRTRHGVS
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RD21B_ARATH
Sequence: MGFLKLSPMILLLAMIGVSYAMDMSIISYDENHHITTETSRSDSEVERIYEAWMVEHGKKKMNQNGLGAEKDQRFEIFKDNLRFIDEHNTKNLSYKLGLTRFADLTNEEYRSMYLGAKPTKRVLKTSDRYQARVGDALPDSVDWRKEGAVADVKDQGSCGSCWAFSTIGAVEGINKIVTGDLISLSEQELVDCDTSYNQGCNGGLMDYAFEFIIKNGGIDTEADYPYKAADGRCDQNRKNAKVVTIDSYEDVPENSEASLKKALAHQPISVAIEAGGRAFQLYSSGVFDGLCGTELDHGVVAVGYGTENGKDYWIVRNSWGNRWGESGYIKMARNIEAPTGKCGIAMEASYPIKKGQNPPNPGPSPPSPIKPPTTCDKYFSCPESNTCCCLYKYGKYCFGWGCCPLEAATCCDDNSSCCPHEYPVCDVNRGTCLMSKNSPFSVKALKRTPAIPFWAKSRKHIA
What is the function of this protein?
Probable thiol protease.
What are the official names of this protein?
Probable cysteine protease RD21B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: ECSCR_BOVIN
Sequence: MGSVRETQLRWAILGFLLLQAASETPSQFSTEAMTLSSSTVADHLPSSPGPTWSQSQKHTSGLSADVPSSGRSSDSMSGDTSHNVTSTSPNMSFRTTADSTVPPSPTSETVLTVAAFGVISFIAILVVVVIVLVSVVSLRFKCRKNKESEDPQKPGSSGLSESGSTANGEKESITLISMKNINMNNSKGCPSAEKVL
What is the function of this protein?
Regulates endothelial chemotaxis and tube formation.  Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2 (By similarity).
What are the official names of this protein?
Endothelial cell-specific chemotaxis regulator, Endothelial cell-specific molecule 2.
What is the protein family that this protein belongs to?
Belongs to the ECSCR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Protein: RDRP_I77AF
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRLNRRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: FUND1_HUMAN
Sequence: MATRNPPPQDYESDDDSYEVLDLTEYARRHQWWNRVFGHSSGPMVEKYSVATQIVMGGVTGWCAGFLFQKVGKLAATAVGGGFLLLQIASHSGYVQIDWKRVEKDVNKAKRQIKKRANKAAPEINNLIEEATEFIKQNIVISSGFVGGFLLGLAS
What is the function of this protein?
Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control.
What are the official names of this protein?
FUN14 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the FUN14 family.
Protein: CCA_PSEFS
Sequence: MKIYKVGGAVRDRLLGIKVTDIDRVVVGATTEEMLAKGFKPVGADFPVFLDPKNGDEYALARTERKSGRGYGGFVFHASPEVTLEEDLIRRDLTINAMAEDDDGNLTDPYHGLRDLEARILRHVSPAFAEDPLRVLRVARFAARYAHLGFTVAPETLELMRQLSESGELEALTPERSWKEISRALMEDQPQVFIQVLRDCAALKTLMPEVDALFGVPQPEAHHPEIDTGVHTLSVLEQAALHKQPLTVRWACLLHDLGKGTTPVDKLPQHIAHEHRGLKLIKAVNERFKVPRDCQELALLVGQYHTHGHRALELKASTLLELLQSFDVYRRPQRFEEFAIACEMDARGRKGLEQRIYPQADYLRGAAKAAREVAVAPLLEKGYKGPELGEALKRERLKALKAYKEQPIL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: SYN_KORVE
Sequence: MEQAPVSTIHEIGKHDGQSVTIKGWLYNLRESGKLLFPIFRDGTGLLQGVLFKKNVSPELFDLVKNLTQESSVIVTGNVRAEQRAPGGYEMDVTALEVVQRVPENEPYPITPKEHGIEFLMEHRHLWVRSQRQAAILRIRGEIVRSAHEFFDKQGFTLTEPPILTPAACEGTSTLFPVDYFGDPAFLTQSGQLYIEATAMALGKVYSFGPTFRAEKSKTRRHLTEFWMVEPEVAFAELDDIMKLAEDFITHIVKSVLERRRDDLKTIERDLSKLENIDTPFPRISYDEAVQMLQEGHAKGELESRFEWGGDLGSPDETYISSKFDRPVMIHRYPVEVKAFYMEPDPNNSKVALCVDVLAPEGYGEVIGGSQRMGSYEKLLARIHEHQLPEESFKWYLDLRKFGGVPHSGFGMGIERAVAWICGLDHVRETIPFARTLHRIYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1B_MOUSE
Sequence: MGFGDLKTPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSGPPPADLCHALRWYNHIKSYEKEKASLPGVKKSLGKYGPSSVEDTTGSGAADAKDDDDIDLFGSDDEEESEEAKKLREERLAQYESKKAKKPAVVAKSSILLDVKPWDDETDMTKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI
What is the function of this protein?
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: TRPB_ALBFT
Sequence: MFEYQQPDPRGHFGIYGGSFVSETLTHAINELKAAYAKYQFDPAFVAEFNYELAHFVGRPSPVYHADRMSREQGGAQIFLKREDLNHTGAHKINNTIGQAMLARRMGKPRVIAETGAGQHGVATATICARYGLECVVYMGSEDVKRQSPNVYRMNLLGATVVPVESGSRTLKDALNEAMRDWVANVDNTFYIIGTVAGPHPYPMMVRDFQSVIGKECLVQMPEMLQAAGCHTTQPDAVVACVGGGSNAMGIFHPYIAHEATRLIGVEAAGLGMDSGKHSASLQRGSPGVLHGNRTYVLQDDNGQVTETHSISAGLDYPGVGPEHAFLKDIGRAEYVGITDQEALAAFHYLCRTEGIIPALESSHAVAYAMKLAKTMRPDQSILVNLSGRGDKDIGTVADLSHADFYCRPSCKGQSVKGADNAQPSANQQVVKVAQ
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: VEMP_CVHOC
Sequence: MFMADAYLADTVWYVGQIIFIVAICLLVTIVVVAFLATFKLCIQLCGMCNTLVLSPSIYVFNRGRQFYEFYNDVKPPVLDVDDV
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: SECA_SINMW
Sequence: MVSLGGFARKLFGSANDRRVRGYKGRVDAINALEAEMKALSDEALAAKTAEFRREIADGKSLDDILVPAFAVVREAARRVLGLRPFDVQLIGGMILHERAIAEMKTGEGKTLVATLPVYLNALAGKGVHVVTVNDYLAQRDAGMMGRIYGFLGMSTGVIVHGLSDEQRRDAYACDVTYATNNELGFDYLRDNMKYERSQMVQRGHFFAIVDEVDSILVDEARTPLIISGPLDDRSDLYNTINEFIPRLSPEDYEIDEKQRSANFSEDGTEKLENMLREAGLLKGESLYDIENVAIVHHVNNALKAHKLFTRDKDYIVRNGEIVIIDEFTGRMMPGRRYSEGQHQALEAKEKVQIQPENQTLASITFQNYFRMYDKLAGMTGTAATEAEEFGNIYGLEVLEVPTNLPIKRIDEDDEVYRTVGEKFKAIIEEIKSAHERGQPMLVGTTSIEKSELLAEMLKKDGFSKFQVLNARYHEQEAFIVAQAGVPGAITIATNMAGRGTDIQLGGNPDMRIQQELSDVEPGAERESREKAIREEVQVLKEKALAAGGLYVLATERHESRRIDNQLRGRSGRQGDPGRSKFYLSLQDDLMRIFGSDRMDGMLQKLGLKEGEAIVHPWINKALERAQKKVEARNFDIRKNLLKYDDVLNDQRKVIFEQRIELMDAESVTDTVTDMRNEVIEEVVAKRIPERAYAEKWDAEGLKADVQQYLNLDLPIVEWVAEEGIAEDDIRERITAAADQAAADRAERFGPEVMQYVERSVILQTLDHLWREHIVNLDHLRSVIGFRGYAQRDPLQEYKSEAFELFQALLGNLRQAVTAQLMRVELVREAPEEPQPLPPMQAHHIDPLTGEDDFAPAGDTLLAVAPTTRDPADPSTWGKVSRNEACPCGSGKKYKHCHGVYEA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: ELO1_YEAST
Sequence: MVSDWKNFCLEKASRFRPTIDRPFFNIYLWDYFNRAVGWATAGRFQPKDFEFTVGKQPLSEPRPVLLFIAMYYVVIFGGRSLVKSCKPLKLRFISQVHNLMLTSVSFLWLILMVEQMLPIVYRHGLYFAVCNVESWTQPMETLYYLNYMTKFVEFADTVLMVLKHRKLTFLHTYHHGATALLCYNQLVGYTAVTWVPVTLNLAVHVLMYWYYFLSASGIRVWWKAWVTRLQIVQFMLDLIVVYYVLYQKIVAAYFKNACTPQCEDCLGSMTAIAAGAAILTSYLFLFISFYIEVYKRGSASGKKKINKNN
What is the function of this protein?
Component of a microsomal membrane bound medium-chain fatty acid elongation system, which extends medium-chain-length fatty acids to long-chain fatty acids.  Component of elongase I, which extends 12-16-carbon fatty acyl-CoAs such as lauroyl-CoA to 14-18-carbon fatty acids by incorporation of malonyl-CoA.
What are the official names of this protein?
Elongation of fatty acids protein 1, 3-keto acyl-CoA synthase ELO1, Very-long-chain 3-oxoacyl-CoA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the ELO family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NUON_ECO5E
Sequence: MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.