PharMolix/UniProtQA huggingface dataset:
Protein: GUAA_ECOHS
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: EX7S_BORPE
Sequence: MASSKQADPQTDARPLPQDFETALAELESLVSAMENGTLPLEQSLSAYRRGVELARVCQDRLAQAEQQVKVLEGDLLRPLDPAALDDE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_BUCAT
Sequence: MISEERLLKILLSPHVSEKTSISMEKFNTVVLKVLNNATKYEIKYAVKKIFDVDVDSIKTLKVKGKKKRQSNRIIQRSHWKKAYIKVKKGCNLDFIGNTE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HEMA_CVMA5
Sequence: MCIAMAPRTLLLLIXCQLVFGFNEPLNIVSHLNDDWFLFGDSRSDCTYVENNGHPKLDWLDLDPKLCNSGKISAKSGNSLFRSFHFTDFYNYTGEGDQIVFYEGVNFSPSHGFKCLAHGDNKRWMGNKARFYARVYEKMAQYRSLSFVNVSYAYGGNAKPASICKDNTLTLNNPTFISKESNYVDYYYESEANFTLEGCDEFIVPLCGFNGHSKGSSSDAANKYYTDSQSYYNMDIGVLYGFNSTLDVGNTAKDPGLDLTCRYLALTPGNYKAVSLEYLLSLPSKAICLHKTKRFMPVQVVDSRWSSIRQSDNMTAAACQLPYCFFRNTSANYSGGTHDAHHGDFHFRQLLSGLLYNVSCIAQQGAFLYNNVSSSWPAYGYGHCPTAANIGYMAPVCIYDPLPVILLGVLLGIAVLIIVFLNVLFYDG
What is the function of this protein?
Structural protein that makes short spikes at the surface of the virus.  Contains receptor binding and receptor-destroying activities.  Mediates de-O-acetylation of N-acetyl-4-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells.  This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell.  May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one.  May become a target for both the humoral and the cellular branches of the immune system.
What are the official names of this protein?
Hemagglutinin-esterase, HE protein, E3 glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the influenza type C/coronaviruses hemagglutinin-esterase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In infected cells becomes incorporated into the envelope of virions during virus assembly at the endoplasmic reticulum and cis Golgi. However, some may escape incorporation into virions and subsequently migrate to the cell surface.
Protein: SPVD_SALDU
Sequence: MRVSGSASSQDIISRINSKNINNNDSNEVKRIKDALCIESKERILYPQNLSRDNLKQMARYVNNTYVHYSGNCVLLSACLHYNIHHRQDILSSKNTASPTVGLDSAIVDKIIFGHELNQSYCLNSIDEVEKEILNRYDIKRESSFIISAENYIAPIIGECRHDFNAVVICEYDKKPYVQFIDSWKTSNILPSLQEIKKHFSSSGEFYVRAYDEKHD
What is the function of this protein?
Part of a Salmonella virulence gene cluster.
What are the official names of this protein?
Virulence protein SpvD, Virulence protein VsdE.
What is the protein family that this protein belongs to?
Belongs to the SpvD family.
Protein: YC60L_SYNY3
Sequence: MASNSTADGKDRFFSALIYVIPLIDAFMFGGFLLQQFPVLQIIYLPIMPLLQFYYQFPFASFIIFIVLFMAVVRNNNISHFIRFNAMQAILIGILLSLFGLIVAYVIQPVFGQGLVTETLYNFAFLGALACGFFGIVQSVLGRYAEIPTISDAAYSQVRF
What are the official names of this protein?
Tic20 family protein.
What is the protein family that this protein belongs to?
Belongs to the Tic20 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRDR_LEGPH
Sequence: MYCPFCHAEETKVVDSRLVADGAQVRRRRECLECHERFTTFETAELIMPLIIKRDGRREPFHIDNLRSGMLRALEKRPVSVDDLEKAIISITEEIRRRGEREIDSQVVGELVMKELFRLDHVAYVRFASVYKRFKDVSDFRQTIDQMKNEDKEKS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: Y1816_BACCR
Sequence: MIVTTTSGIQGKEIIEYIDIVNGEAIMGANIVRDLFASVRDVVGGRAGAYESKLKDARDIAMDEMKELAKQKGANAIIGIDVDYEVVRDGMLMVAVSGTAVRI
What are the official names of this protein?
UPF0145 protein BC_1816.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: Y1407_HAEIN
Sequence: MLMNLPEILKNQKARARKFKPVKMSKRTELWYRQQLKQFVKMMTNDVERALQQPQGSFFMDDAKGFQAISAKALMKVLEKYEKSDRTSQAENIANGFVSRGDAQNHAEVSTNLKNQTGIDLSAYLRNSPNITEKVNALTAGNIQLIKSIRSQYLDKVQNAVMQAMVRGSLNKDLAAQIKDLGKTTEKRAMFIARDQSSKLNAALTQARHEEVGIKKYMWSASLDERVRESHAEKDGQIFEYANPPADTDHPGHDFNCRCVQIPVLDNNEQIVKNSPIVSQQEKQQMRSEWSDDFPDTIIDRKLGDATSHPLYENAKKGSIEDAYQLAKDLVTDDAVNKLKQLVGNKNAILIPVHAEEAVGQNMIPVAIATVLSKKLHIPVDLSIVQATKVSRTGGDGWHRLVYSPAFDGIVPKDKYAIILDDTQTQGGTLASLKGYIIKEKLLHLML
What are the official names of this protein?
Uncharacterized protein HI_1407.
What is the protein family that this protein belongs to?
To E.coli plasmid IncP-alpha RP4 protein TraN.
Protein: IMB1_YEAST
Sequence: MSTAEFAQLLENSILSPDQNIRLTSETQLKKLSNDNFLQFAGLSSQVLIDENTKLEGRILAALTLKNELVSKDSVKTQQFAQRWITQVSPEAKNQIKTNALTALVSIEPRIANAAAQLIAAIADIELPHGAWPELMKIMVDNTGAEQPENVKRASLLALGYMCESADPQSQALVSSSNNILIAIVQGAQSTETSKAVRLAALNALADSLIFIKNNMEREGERNYLMQVVCEATQAEDIEVQAAAFGCLCKIMSLYYTFMKPYMEQALYALTIATMKSPNDKVASMTVEFWSTICEEEIDIAYELAQFPQSPLQSYNFALSSIKDVVPNLLNLLTRQNEDPEDDDWNVSMSAGACLQLFAQNCGNHILEPVLEFVEQNITADNWRNREAAVMAFGSIMDGPDKVQRTYYVHQALPSILNLMNDQSLQVKETTAWCIGRIADSVAESIDPQQHLPGVVQACLIGLQDHPKVATNCSWTIINLVEQLAEATPSPIYNFYPALVDGLIGAANRIDNEFNARASAFSALTTMVEYATDTVAETSASISTFVMDKLGQTMSVDENQLTLEDAQSLQELQSNILTVLAAVIRKSPSSVEPVADMLMGLFFRLLEKKDSAFIEDDVFYAISALAASLGKGFEKYLETFSPYLLKALNQVDSPVSITAVGFIADISNSLEEDFRRYSDAMMNVLAQMISNPNARRELKPAVLSVFGDIASNIGADFIPYLNDIMALCVAAQNTKPENGTLEALDYQIKVLEAVLDAYVGIVAGLHDKPEALFPYVGTIFQFIAQVAEDPQLYSEDATSRAAVGLIGDIAAMFPDGSIKQFYGQDWVIDYIKRTRSGQLFSQATKDTARWAREQQKRQLSL
What is the function of this protein?
Importin beta subunit that functions in nuclear protein import through association with the importin alpha subunit, which binds to the classical nuclear localization signal (cNLS) in cargo substrates (PubMed:7622450).  Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by importin beta through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism (PubMed:8521485).  At the nucleoplasmic side of the NPC, GTP-Ran binds to importin beta and the three components separate, leading to release of the cargo (PubMed:15864302).  Importin alpha and beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin beta.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (PubMed:11423015).  Mediates the nuclear import of histones H2A and H2B (PubMed:11309407).  Mediates the nuclear import of transcription factor GCN4 (PubMed:14648200).
What are the official names of this protein?
Importin subunit beta-1, Importin-95, Karyopherin subunit beta-1, Karyopherin-95.
What is the protein family that this protein belongs to?
Belongs to the importin beta family. Importin beta-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nuclear pore complex.
Protein: SYY_SYNE7
Sequence: MTDSWTWLQRGTHEIFPDQPESADPDVSLLARLQQGDRPLRIKLGIDPTGSDIHLGHSIIFRKLRQFQDAGHTAVLIIGDFTARIGDPTGKSEVRRQLTAEDVQRNAETYLDQLRPILDFETPGRLEIRYNSEWLAGLDLAKILELLGTMTVGQMLAKEGFSERYDKGTPVYLHEFLYPLMQGYDSVAVQSDVELGGTDQKFNIAVGRDLQRHFGLQPQFGLLLPILIGLDGSQKMSKSLGNYVGLNEDALSMYSKLEKVPDALVADYFELLTSQDLAALPENPRDRQKLLALDVVSQYHGAEAAAAAQKAAQELVQGSAVQAEAVPEFPLSQVNFPAKAFYLVSAVGLGLTSSEARRQIQGGAVRLDGQKLDDPNHIFEAPTALKGRVIQVGKKKFVRLVL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP7_ROTHJ
Sequence: MYGIEYTTILIFLISIILLNYILKSVTRIMDYIIYRFLLITIALFALTRAQNYGLNLPITGSMDTVYTNSTQEEVFLTSTLCLYYPNEASTQINDGDWKDSLSQMFLTKGWPTGSVYFKEYSSIVDFSVDPQLYCDYNLVLMKYDQSLELDMSELADLILNEWLCNPMDITLYYYQQSGESNKWISMGSSCTVKVCPLNTQTLGIGCQTTNVDSFEMVAENEKLAIVDVVDGINHKINLTTTTCTIRNCKKLGPRENVAVIQVGGSNVLDITADPTTNPQTERMMRVNWKKWWQVFYTIVDYINQIVQVMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: MET31_YEAST
Sequence: MKLAQDMNVDEIFLKQAAEAIAVISSSPTHTDPIIRELLHRIRQSSPLSAVIPAPENVLKAGEPENMARGLIRIPETQTKRTGGNNHSKEGAQLYSCAKCQLKFSRSSDLRRHEKVHSLVLPHICSNCGKGFARKDALKRHSNTLTCQRNRKKLSEGSDVDVDELIKDAIKNGTGLL
What is the function of this protein?
Auxiliary transcriptional regulator of sulfur amino acid metabolism.  Involved in the transcriptional activation of MET28.
What are the official names of this protein?
Transcriptional regulator MET31, Methionine-requiring protein 31.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LPXD_RHIL3
Sequence: MEQNVFFLPHEGLKLAELAEFLGAELVNSDYADVIVRSVAPISRARAGDVCYILSRRSRDELATCEASAVICDKALADLVPQHLPVMLSSNPHAAFAMAGGLFYPAALRPVAFSGESEIAPSAVIDPSARLEKGVIVEPMAVIGAHAEIGEGTRIGAHSIIGPNVKIGRDCSIAAGASIICALLGNGVIIHNGARIGQDGFGYAPGPRGMIKIVQIGRVIIQDNVEIGANTTIDRGAMDDTVIGEGTKIDNQVQIGHNVQIGRHCAIVALVGIAGSAKIGNGVQIGGQVGIKGHVTIGDGVQIAAQSGIMTDLAAGGQYGGTPGRPLNDYLRDVAQQMSKTKLRGKKPGGEQND
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: LAP1_CHAGB
Sequence: MKVTNASLLALLLPAVSGRFVETGEPDRSILYPDGLPQPTETGEKYHIELSPGDTRWVTEDEKWELRRSGKRFFDITDHPDLGALRAMTASRKKSVFPEKPKYQKELKPFLAELSKTEMEDHLTTFTSFHTRYYKSDYGRQSSEWLLKQVRDTIEKAGADKHVRAEHFKHPWGQNSIIATIPGKTNATVVIGAHQDSINLWLPSVLAAPGADDDGSGTVTILEAFRVILQSEDIVKGNHENTLEFHWYSAEEGGLLGSQAIFSSYEKEGRDVKAMLQQDMTGFITRTLDAGKPESVGVIVDFVDPNLTQFIKVVIDEYCSIPYVETKCGYACSDHASASKAGYPSAFVIESAFEYSDNHIHSTEDLIKYLSFDHMLQHARMTLAFGYELAFTDFAALEKPDHSDSL
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IBPA_ECOSE
Sequence: MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB_LITCT
Sequence: GGSDVSAFLAKVDKRAVGGEALARLLIVYPWTQRYFSTFGNLGSADAISHNSKVLAHGQRVLDSIEEGLKHPZBLKAYYAKLSERHSGELHVDPANFYRLGNVLITVMARHFHEEFTPELQCALHSSFCAVGEALAKGYH
What is the function of this protein?
The beta chain is a component of adult hemoglobins B.  And C.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PAND_BEII9
Sequence: MRKVMAAKLHGIHVTAADLDYHGSITLDPDHCEKAGLLPLEFVDIWNKNSGARISTYVIFGERYSRCCILNGAAARTCQVGDEIIICSSHYIEAERIADFQPKILTFDKGNHIVETLSYVVERDGTGRYHFDIVNEGGQSLPIPVKAHGR
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCR5_PAPHA
Sequence: MDYQVSSPTYDIDYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLLFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMT_FRATF
Sequence: MKKLNIIFAGTPDISAQVLKDLYKSQHNIQAVLTQPDRAKGRGKKVQFSPVKEVALANHTPVFQPLSFKKNPEVLEQIKQLKPDVIVVIAYGIIVPQEFLDIPRYGCLNIHVSLLPKWRGAAPIQRAIQAGDTKTGVCIMQMDAGLDTGDILNTLEIEIQETDTSQTLHDKFAKLSIKPLLETLEKIEIIKPEPQQGEPTYAHKITKQEGLIDFTKSAWRISCHIRAFTPWPGAYFILDDEAIKVGEFEILYQNTDNRKAGTIIDIYRSGFDIATSDKIIRFRQLQFPNKKMLNIVDILNGKDLDKYIGYKLG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RS5_HAHCH
Sequence: MTNNEQQKGAELQEKLVQVNRVAKVVKGGRIFGFTALTVVGDGNGKVGFGRGKAREVPVAIQKAMDAARKNMITVTLNGNTLQYPVKARHGSAKVFMQPASEGTGIIAGGAMRAVLEVAGVQNVLAKCYGSTNPVNVVRATFEGLKAMQAPEEIAAKRGKTVEEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SYH_SALSV
Sequence: MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGAEVFGLQGPDIDAELIMLTARWWRALGIADHVSLELNSIGSLEARANYRDALVAFLEQHQETLDEDCKRRMYTNPLRVLDSKNPDVQALLNDAPALGDYLDDDSREHFAGLCKLLDAAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFIASPVVDIYLVAAGAQTQSAAMTLAERLRDEMPGVKLMTNHGGGNFKKQFARADKWGARIALVLGESEVADGTVVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEAH_SALCH
Sequence: MTWFIDRRLNGKNKSTVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTDDISEPMFHQGRGGLRHRVHPGNDHFIQNDRIERPQGGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKKNQHRQLNEYKTHRAGFTSNGVPANISVVRSLQNSLARRTAMTAGKRRELHALETELETISHSEPAQLLEEERLRREIAELRTKIERVPFIDTFDLRYKNYEKRPEPSSQAVMFCLMDVSGSMDQATKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYDPGQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQATFDNFAMQHIRDQEDIYPVFRELFQKQSANQSA
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: GUF1_ASPOR
Sequence: MRGCLQLARWLSAGPKCPAASLPKAPSGLYNTIRSFTSSAQLASRARAASKPASDLETRIAQIPIDRYRNFCIVAHVDHGKSTLSDRLLELTGTIQPGSNKQVLDKLDVERERGITVKAQTCTMIYNHNGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGIQAQTVANFYLAFAQGLELIPVINKVDLPSAEPEKALQQMKTSFELDTENAVMVSAKTGLNVEQLLPTVVEKIPAPVGDTQKPLRMLLVDSWYDSYKGVICLVRIFDGEVRAGDQLVSFATGIKYYVGEVGIMYPTETSQTVLRAGQVGYIFFNPGMKRSQEAKIGDTYTKVGSEKAVEPLPGFEEPKAMVFVAAYPVDADHFEHLEDSINQLMLNDRSITVQKESSEALGAGFRLGFLGTLHCSVFEDRLRQEHGASIIITPPSVPVKVMWKDGREEIVTSPARFPEEDDLRSKVAEIHEPYVLATLTFPDEYLGKVIELCEANRGVQQTLEYFTSTQVILKYELPLAQLVDDFFGKLKGSTKGYATLDYEESAWQPSNIVKLQLLVNKAPVDAVARVVHYSQIERLGRKWVTKFKQHVDRQLFEVVIQAAVGRKVIARETVKPYRKDVLAKLHASDVSRRRKLLEKQKEGRKRLRAVGNVVIEQKAFQNFLAK
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor guf1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase guf1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SLX4_PENRW
Sequence: MTSMADVIILSSSPHPPRSPGPGRHDTKPVSHALPRSATPPPIRSTSDLSQPHTRSRFFPTPVASNKCPDGASKPKKRLTKDPASETSKQTAPSKPRREAKKVAGAPGTTALGEPQPEAVGKKNDAVKPTKSRSRRNAKSKDSGNMTLAGKVTKTSGDLPSKKSSKGGKKTVATKLSPSEDTSEKSTPKESNALGKDEVLRLDEAMRRRMDWTPPRETAYEEIATVTDRGSQDQDRDSSSSGGFGKLVSDYNYSGSALHPRDFVQNANGEGPTKRRRIELVNPEIQALLNGRYSDSSDQSSGQGENTGKPKKTTKGKPKKFTTLTARMTAQYSKNDAEEDEPVIDCLAGIRTTKGRQKKAKEIEKQSSSTVLSPEAAVEFLNDQDLIFGSCSQLEKDDSPETLRETQQAIRVPEGPSYSKGTHNKDPSAIQESSTRFVSKLAGTRNLWCVGARDTEGSLIQPETLNVVDLTNGEESPGKKSQDDAENPSHNTLQSDWYELEFADIDSPSEKRPSPLPTESVLDSDTQVQAPAPIPADTATATATATAVVKAAKPAKGANDTPTEAVDSQPASSQAPPMPQYTGFTDAELSKQVSSYGFKAVRGRKKMIDLLRQCWESKHGSGSNAASDSQLICQLEQQEEPASKMDNVPKSTSAAKTKATVKPKAGTSIRNRKSLDATKSTSASRTNLQTSPKKNSREKPITGTSTSFIDVEEIQDSEEEIIPSPSQVQKHYTDIYSKSKTGSWVQDHSLDILTKTPSPSPTKRKVVSSDIPAKRPPSSASIATTRMTESSKEISLAEISAQITQAVRLQPQLSPLSSSRGSRSRPTWHEKILMYDPIVLEDFTAWLNIEGLGLVGEDREVGTASVREWCESKGICCCWKKNAS
What is the function of this protein?
Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNH3_MACCJ
Sequence: MTNKVYLLTDEQSKKIEHVLPTSDTTNLPQGTKYRTKISGHTVTLYNSNKLMIQGADSEVIGEQILSKAGIQLTQQLPDSNSTSKHNVSIESIQYDNYNCIGSDEAGSGDYFGPMTVVASYVSKKNAEILKVLGVMDSKNLKDRQIIELAEQIIPIIPHSLLVLDNIKYNERKQMGWSQVKMKAVLHNEAIKNVLNKIEEPVDYIVIDQFAVQGVYENYALGAIPERNKTKFETKGESKAIAIAASSIIARYAFVKHFEQIIKETGISITKGAGAKVDVEAAKIIKLRGIDYLDTITKKDFKNREKALKLIKK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_HELP2
Sequence: MDALEITQKLISYPTITPKECGIFEYIKSLFPTFKTLECGENGVKNLFLYRIFNPPKEHIKGKHAKENVKPLHFCFAGHIDVVPPGDNWQSDPFKPIIKEGFLYGRGAQDMKGGVGAFLSASLNFNPKTPFLLSMLLTSDEEGPGIFGTKLMLEKLKEKDLLPHMAIVAEPTCEKVLGDSIKIGRRGSINGKLILKGVQGHVAYPKKCQNPIDTLASVLPLISGVHLDDGDECFDPSKLVITNLHAGLGANNVTPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPHTLELESSSSPFITASHSKLTSVLKENILKTCRTTPLLNTKGGTSDARFFSAHGIEVVEFGAINDRIHAIDERVSLKELELLEKVFLGVLEGLSEA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.