PharMolix/UniProtQA huggingface dataset:
Protein: PAX_I57A1
Sequence: MEEFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPKEAKKQLKKDLKSQGQCAGSPTKVSRRTSPALRILEPMWMDSNPTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: CATB_BOVIN
Sequence: MWRLLATLSCLLVLTSARSSLYFPPLSDELVNFVNKQNTTWKAGHNFYNVDLSYVKKLCGAILGGPKLPQRDAFAADVVLPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGMPCTHQY
What is the function of this protein?
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (PubMed:1856234).  Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity).  Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity).  Has also been implicated in tumor invasion and metastasis (By similarity).
What are the official names of this protein?
Cathepsin B, BCSB.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Melanosome. Secreted, extracellular space. Apical cell membrane; Peripheral membrane protein; Extracellular side. Note=Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells.
Protein: YQGF_BURVG
Sequence: MSGASARDATFLAFDYGEKRIGVALGNALTRSARALVVIPNLNREHRFKAVGELLAEWRPDALVVGLPMHPDGTPHDMTQQAKRFGNQLNGRFGLPVTWVDERYSSVEAEAGLRERNVRGRARTDMLDAEAARVILQQYFDELSDHEHH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORP4C_ARATH
Sequence: MKKHVMLVKPFSLEDEKDSENTPPNLIQRILSLFKNVRPGSDLTNFQLPPQMNLARSQLQCYGEIVYSFDGHDLLGECSRRDKPIERMKAMVTWYISTLRPLIFGLAPYNPVIGETHHVSNGHINVLAEQISHHPPVSALHATHEKENVDVLLCQYFTPKFRGAYVDVEVKGKRVVKLLNHKETYEMNQPKLLMTFLPAMGAHWAGKIVIKCPETGLGAELQLLSDSFLSRFTGNNKRAIKGKIFESSSRKQLYEISGHWDRTVTAKNTKTGQLEVIYKASENIAKLKTPIVENLQEVSESESAVVWGEVSEGIVTNNWEKAREAKRDVEEKQRESLRKRKASGQSWIPKHFSVARTGKDWDCVPLQPTVPRAPIVVPL
What is the function of this protein?
May be involved in the transport of sterols.
What are the official names of this protein?
Oxysterol-binding protein-related protein 4C, OSBP-related protein 4C.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
Protein: RSMB_ECOHS
Sequence: MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQWQSIVEANNQRPPMWLRINRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVHALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKTGGTLVYATCSVLPEENSLQIKAFLQRTADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_XANCP
Sequence: MKCRLIATGERAPAWVAQGFAEYQKRLSHWMPLELVEIEPGLRGKGRDAQRAIDDEGRRVLAALPKNAHVVALDVPGRPLSSEQLAQRMEHWRGQGRDLAFLIGGPEGHAADVVKSANESWSIGPLTLPHMLVRLIVAEQLYRAAAMLANHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_BLAGS
Sequence: MAVGKNKRLSKGKKGLKKRTQDPFSRKDEYSVKAPSTFAIRDVGKTLVNRTTGLKNANDSLKGRIFEVSLADLQNDEDHAFRKVKLRVDEVQGKNCLTNFHGLDFTSDKLRSLVRKWQTLIEANVTVKTTDDYLLRLFAIAFTKRRPNQIKKTTYARSSQIRAIRKKITEIIQREASTRTLAQLTKLIPEVIGREIEKATHGIYPLQNVHIRKVKLLKSPKFDLGALLALHGESSTDDKGQKVEREFKEQVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_MYCS2
Sequence: MSANSDVATRVIPCLDVDNGRVVKGVNFENLRDAGDPVELAAAYDAEGADELTFLDVTASSSGRSTMLEVVRRTAEQVFIPLTVGGGVRSVDDVDVLLRAGADKVSVNTAAIARPELLAEMARQFGSQCIVLSVDARTVPKGEQPTPSGWEVTTHGGRRGTGIDAIEWATRGAELGVGEILLNSMDRDGTKAGFDLKMLSAVRAAVSVPVIASGGAGAVEHFAPAVQAGADAVLAASVFHFRELTVAEVKASMKAAGITVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYH14_MOUSE
Sequence: MAAVTMSVSGRKVASRPGPVPEAAQSFLYAPRTPNVGGPGGPQVEWTARRMVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTMSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDIAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGLLPEEITAMLRTVSAVLQFGNIVLKKERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGSHPKFQRPRNLRDQADFSVLHYAGKVDYKASEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRNWQWWRLFIKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERTRLAEQLRAEAELCSEAEETRARLAARKQELELVVTELEARVGEEEECSRQLQSEKKRLQQHIQELESHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERRLLEERLAEFSSQAAEEEEKVKSLNKLRLKYEATISDMEDRLKKEEKGRQELEKLKRRLDGESSELQEQMVEQKQRAEELLAQLGRKEDELQAALLRAEEEGGARAQLLKSLREAQAGLAEAQEDLEAERVARAKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKALEEESRAHEVSMQELRQRHSQALVEMAEQLEQARRGKGVWEKTRLSLEAEVSELKAELSSLQTSRQEGEQKRRRLESQLQEVQGRSSDSERARSEAAEKLQRAQAELESVSTALSEAESKAIRLGKELSSAESQLHDTQELLQEETRAKLALGSRVRALEAEAAGLREQMEEEVVARERAGRELQSTQAQLSEWRRRQEEEAAVLEAGEEARRRAAREAETLTQRLAEKTEAVERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQRKFDQLLAEEKAAVLRAVEDRERIEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKNVHELERARKAAEQAASDLRTQVTELEDELTAAEDAKLRLEVTVQALKAQHERDLQGRDDAGEERRRQLAKQLRDAEVERDEERKQRALAMAARKKLELELEELKAQTSAAGQGKEEAVKQLKKMQVQMKELWREVEETRSSRDEMFTLSRENEKKLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAEEVASGNLSKAATLEEKRQLEGRLSQLEEELEEEQNNSELLKDHYRKLVLQVESLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARARQKMLIAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQVRDQLEKSNLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEEAEGAEPGSAPGQEPEAPPPATPQ
What is the function of this protein?
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.
What are the official names of this protein?
Myosin-14, Myosin heavy chain 14, Myosin heavy chain, non-muscle IIc, Non-muscle myosin heavy chain IIc, NMHC II-C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: NANE1_SALTY
Sequence: MSLLARLEQSVHENGGLIVSCQPVPGSPMDKPEIVAAMAQAAASAGAVAVRIEGIENLRTVRPHLSVPIIGIIKRDLTGSPVRITPYLQDVDALAQAGADIIAFDASFRSRPVDIDSLLTRIRLHGLLAMADCSTVNEGISCHQKGIEFIGTTLSGYTGPITPVEPDLAMVTQLSHAGCRVIAEGRYNTPALAANAIEHGAWAVTVGSAITRIEHICQWFSHAVKR
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase 1, ManNAc-6-P epimerase 1.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: MOAA_RHOJR
Sequence: MTAVAMGIPTVRSSVSLAGRPDVDQLVDRFGRVARDLRVSITEKCSLRCTYCMPEEGLPAIPAENLLTANEIVRLVDIAVHRLGVREVRFTGGEPLMRVDLEQMIAGCAERAPGIPLAMTTNAVGLEHRAAGLARAGLTRVNVSLDSVDREHFARLTRRDRLPSVIAGIRAAARAGLAPLKINAVLMPETLSGAADLLEWCLSEGVALRFIEEMPLDADHEWARENMVAADRLLAVLGERFTLTEHGREDPSAPAEEWLVDGGPATVGIIASVTRSFCSDCDRTRLTAEGTVRSCLFSDQEIDLRAALRSGAGDEELAQLWRGAMWNKWAGHGINADGFAPPQRSMGAIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: CP1A1_ORYLA
Sequence: MALMVLPFIGPLSVLEGLIALTTVCVVYLLLKHFNKEIPGGLRQLPGPTPLPIIGNLLKLGSKPYLSLTEMSKRFGDVFQIQIGMRPVVVLSGNETVRQALIKQGDDFSGRPDLYSFQFINDGKSLAFSTDQAGVWRARRKLAYSALRSFSSLEGSNAEYSCMLEEHICKETEHLVKEIEKVMKTEGKFDPYRYIVVSVANVICGMCFGRRYDHHDQELVGLVNLSEDFVQVTGSGNPADFIPALRYLPSKAMKKFVEINNRFQSFVQKIVNEHSATYDKDNIRDITDSLIDHCEDRKLDENSNIQMSDEKVVGIVNDLFGAGFDTISTALSWAVGYLVAYPDIEKGLFEEIKENIGLNRNPTISDRSNLPLTDAFILEIFRHSSFLPFTIPHCTTRDTSLNGYYIPKDTCVFINQWQINHDPKLWQDPSSFNPDRFLSEDGSEVNRLDGEKVMVFGLGKRRCIGEVIARNEVFLFLAIMIQKLCFEEMPGEPLDMTPEYGLTMKHKRCNVRASLRLKDGC
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: YX07_CAEEL
Sequence: MVISSNAFIVGRVGELDLITAGWHFLQRTMNNEDRRGFEKMISMPGFCVKKFEETYLLKRVNPFAQTEEGRIIKFNSSDCPCGKSQDVHNISAMKDQLSNFLDKWENVHEKFSLPTGSSELTTSKTPIDVDTKEQENRLKQKAEAAPKSTPIENHKKNIQALCKQNAVAEQCLWNVYHVSGKPAEKKEQRNDMDRNISGVSVKDYETLKNFEDKSPPQAENASSSKKDEPISVECTDETSSRLSPATDISHEMAEHGTPDSGMISDVSEIKVLPAGKIEKKLIKELNPEMMVGRDGRRYRQKLREAEKQATVEFKLENFEQTNGEAQSVENDILTGKEKRRLKDKLRKEKKEQSKLFVEKDLEKNKESSSASLSTNKLAESPTEADKNSNVIHTNIKPKDICIETEYPANNDNKKKSEVMFSSTVTNVFGRNENQTSFDVKEHTVDSFELLPGEYRISNFGQQMADTTSAEMTALGKMPQEAGEVKPTVREHSGANFLQRERNFPLSLKTTVIANSPEGDIEGKRLSKGQKRRARNKANKGVYVVNENGSHSIELLPGEYKLLELDENKKIQEFPIDTRHYMRDDQTGGGSKIVEQGQRTKKKKNFYVAGNLSKNILDNGKWLAYVIDDKNSDGVPRVGEVSTEEVQETIKLLDSKISHNAIQDNSCSEDFEFGSSSSTNFVTGSSRSLLPELDADFVRKTLADYEENATEDAAENNNEVFESASEELEMFMNSEGIAPNFHSEFAKKTSPLLVGNAEFKDFCSKYSNSKYDNKTISKLVKKYIDTRIVHHYERFKKLADRESHRIAKSWTKIYETSSYSLMVMLYTNSPSSSVGFSDLEEILFNDR
What are the official names of this protein?
Uncharacterized protein C03B1.7.
Protein: MNMA_EHRRG
Sequence: MLDDFKIDLLVKNKPPTSTTAVVAMSGGVDSSVAAALLHKLGYKVIGITLQLYNNNKNSNTKGACCGSLDTKDAKQVASSMGFPHYTLNYEKVFREEVIEDFIDTYTQGKTPIPCIKCNQVIKFRDLLNATKSLGADVLVTGHYIRKIEQDDDIYVYSSKDTKKDQSYFLFATTVEQLRLLRFPLGNFHKEDIRKLAKYFNLQVANKPDSQNICFVTDTYKKTIAELRPHTIKKGNIIDINGNILSQHNGIVNFTIGQRKGIGISSKAPLYVIKLNPDTNEVTVGPKSALLQNKLYIREINWLAKEKIPHNGLNVKVKLRSSHSGSPATIFPNNNNTATILLQDSYCTVTPGQACVIYDHDRMLGGGWIC
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADB_SHEPC
Sequence: MIYQSPTIQVELLEDNIAKLCFNAPGSVNKFDRETLASLDAALDSIKQNSNIKALVLTSSKDTFIVGADITEFLGLFAQDDAVLLSWVEQANAVFNKLEDLPFPTASAIKGFALGGGCETILATDFRIADTTAKIGLPETKLGIIPGFGGTVRLPRVIGADNALEWISTGNDQRAEDALKVGAVDAVVAPEALEAAAIQMLKDAVAEKLDWQARRNRKLSALTLPKLEAMMSFTTAKGMVFAVAGKHYPAPMAAVSVIEQASTKGRAEALQIEHQAFIKLAKTDVAKALIGIFLNDQLVKGKAKKAGKLAKEVKNAAVLGAGIMGGGIAYQSASKGTPIVMKDIAQPALDLGLNEAAKLLSAQVARGRSTPEKMAKVLNNITPSLDYAALKHSDVVVEAVVEHPKIKAQVLAEVEGYVSEDAIIASNTSTISINLLAKSMKKPERFCGMHFFNPVHKMPLVEVIRGEHSSEETIASVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFNGLLAEGGDFAAIDKVMEKQFGWPMGPAYLLDVVGLDTGHHAQAVMAEGFPDRMGKSGTDAIDVMFENKRLGQKNGKGFYVYSVDSRGKPKKDVDPTSYGLLKDAFGELKTFEADDIIARTMIPMIIETVRCLEEGIVASPAEADMGLVYGLGFPPFRGGVFRYLDTMGVANFVALADKYAHLGGLYQVTDAMRTKATNNGSYYQA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: CYAY_AZOVD
Sequence: MSLTEARFHELIDDLQQNVEDVFEDSDLDVDLENSAGVLSVRFENGSQLILSRQEPLRQLWLAARSGGFHFDYDEAGGRWICDASGDSLGELLARVTLEQIGEELEFPEL
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: ARGC_PSEAE
Sequence: MIKVGIVGGTGYTGVELLRLLAQHPQARVEVITSRSEAGVKVADMYPNLRGHYDDLQFSVPDAQRLGACDVVFFATPHGVAHALAGELLDAGTRVIDLSADFRLADAEEWARWYGQPHGAPALLDEAVYGLPEVNREKIRQARLIAVPGCYPTATQLGLIPLLEAGLADASRLIADCKSGVSGAGRGAKVGSLFCEAGESMMAYAVKGHRHLPEISQGLRRASGGDVGLTFVPHLTPMIRGIHATLYAHVADRSVDLQALFEKRYADEPFVDVMPAGSHPETRSVRGANVCRIAVHRPQGGDLVVVLSVIDNLVKGASGQALQNMNILFGLDERLGLSHAALLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAG1_HUMAN
Sequence: MAQRGGARRPRGDRERLGSRLRALRPGREPRQSEPPAQRGPPPSGRPPARSTASGHDRPTRGAAAGARRPRMKKKTRRRSTRSEELTRSEELTLSEEATWSEEATQSEEATQGEEMNRSQEVTRDEESTRSEEVTREEMAAAGLTVTVTHSNEKHDLHVTSQQGSSEPVVQDLAQVVEEVIGVPQSFQKLIFKGKSLKEMETPLSALGIQDGCRVMLIGKKNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQETERLQSTNFALAE
What is the function of this protein?
Co-chaperone for HSP70 and HSC70 chaperone proteins.  Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release.  Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:27474739, PubMed:9873016, PubMed:24318877).  Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity (PubMed:12724406).  Markedly increases the anti-cell death function of BCL2 induced by various stimuli (PubMed:9305631).
What are the official names of this protein?
BAG family molecular chaperone regulator 1, BAG-1, Bcl-2-associated athanogene 1.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. Cytoplasm. Note=Isoform 1 localizes predominantly to the nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus. Note=Isoform 2 localizes to the cytoplasm and shuttles into the nucleus in response to heat shock. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm. Nucleus. Note=Isoform 4 localizes predominantly to the cytoplasm. The cellular background in which it is expressed can influence whether it resides primarily in the cytoplasm or is also found in the nucleus. In the presence of BCL2, localizes to intracellular membranes (what appears to be the nuclear envelope and perinuclear membranes) as well as punctate cytosolic structures suggestive of mitochondria.
Protein: HLDE_BRASB
Sequence: MFDFDDLSQAIARQTVLCVGDLMLDEFVYGEVSRISPEAPAPVIAVQRSEINIGGAGNVARNIAALGARCIFVGLVGDDAAAAQLEAELAREPGIETVLVRDASRPTTRKVRFVSEHFSAHMLRADWERAAPASGEIEQRLIDAIVPRLARADIVLLSDYAKGVLTARVLRNVIDAARRAGKRVIVDPKSANLAIYRGASVLTPNRKEFSEATRSRAETEQEIAAAAQDAIYLADCEAILVTQSERGMTLVPRQGDAIHVPAYPVKVRDVSGAGDTVVAVLAATLAAGAGWEEALRMASAAAAVAVSKQGTASVTSAELRRKILPHAYRAAEEKIIAGDGEILARVEGWRSEGLRVGFTNGCFDILHPGHVKVLTAARAACDRLVVGLNSDASVKRLKGESRPVQDERARAEVLAALEAVDLVAIFTEDTPLRLIELVRPSVLVKGGDYTREQVVGHEVVEAGGGEVILIDILKGHSTTALVDRARSDGR
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: ADD_ECOLI
Sequence: MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARHGLHYVELRFSPGYMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHRDQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: RL16_PROMT
Sequence: MLSPKRTKFRKQQRGRMRGVATRGNKIAFGQFALQAQDCGWVTSRQIEASRRAMTRYVKRGGQIWIRIFPDKPVTMRPAETRMGSGKGNPEFWVAVVKPGRILFEMGGDEITEAIAKEAMRLAQYKLPVKTKFISLDEDLNKGNYKPAKTPVTADDSESSS
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: FENR_STRSY
Sequence: MTQVYDITIIGGGPVGLFAAFYAHLRQAKVKIIDSLPQLGGQPAILYPEKAILDIPAFPSLTGQELTDNLLAQLAPFDTTICLNETLTAIEPGETITLTTNKGNHQTKTLIIAMGGGAFKPRPLEIDGADSFDNVHYHVSNIQQYADKDIVVLGGGDSAVDWSLAFEKIAKTTQIIHRRDNFRALEHSVEELKQSSVTIHTPFIPKGLSGENGRASAIDFDKVKSEDKLTLSFDHLFVNYGFKSSVGTLKEWGLELNRHRIVVNSKQETSVPGIYAIGDCCFYEGKIDLIATGLGEAPTAVNNAMNYLNPNEKVQPKHSTSL
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: RS16_RICAE
Sequence: MAVKIRLARGGAKKRPFYRVVVANATAPRDGDFLEKVGTYDPMLASDNSERVVLKKDRIEYWLGTGAKPTERVAKFIEQAGVTLPEKVKKEMEVKAKNRKARLSKKEAKEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: CP2DQ_MOUSE
Sequence: MGLLVGDDLWAVVIFTAIFLLLVDLVHRRQRWTACYPPGPVPFPGLGNLLQVDFENIPYSFYKLQNRYGNVFSLQMAWKPVVVVNGLKAVRELLVTYGEDTSDRPLMPIYNHIGYGHKSKGVILAPYGPEWREQRRFSVSTLRDFGLGKKSLEQWVTEEAGHLCDAFTKEAEHPFNPSPLLSKAVSNVIASLIYARRFEYEDPFFNRMLKTLKESLGEDTGFVGEVLNAIPMLLHIPGLPDKAFPKLNSFIALVNKMLIEHDLTWDPAQPPRDLTDAFLAEVEKAKGNPESSFNDKNLRIVVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHQEIDEVIGHVRHPEMADQARMPYTNAVIHEVQRFADIVPTNLPHMTSRDIKFQDFFIPKGTTLIPNLSSVLKDETVWEKPLRFYPEHFLDAQGHFVKHEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPDGQPRPSDYGIYTMPVTPEPYQLCAVAR
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2D26, CYPIID26.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: PROB_ECOSE
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMIM7_HUMAN
Sequence: MIGDILLFGTLLMNAGAVLNFKLKKKDTQGFGEESREPSTGDNIREFLLSLRYFRIFIALWNIFMMFCMIVLFGS
What are the official names of this protein?
Small integral membrane protein 7.
What is the protein family that this protein belongs to?
Belongs to the SMIM7 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SQASE_ECOLI
Sequence: MDTPRPQLLDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQTYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLTALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRIKQWNQEGVQFLAYINPYVASDKDLCEEAAQHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCGGWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWTGEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI
What is the function of this protein?
Catalyzes the hydrolysis of sulfoquinovosyl diacylglycerides (SQDG) to sulfoquinovose (SQ), which is then degraded by E. coli through the SQ Embden-Meyerhof-Parnas (SQ-EMP) sulfoglycolysis pathway as a source of carbon and sulfur.  Therefore, is likely involved in the utilization of the sulfoquinovose headgroup found in ubiquitous plant sulfolipids.  Is also able to hydrolyze simple sulfoquinovosides such as 1-sulfoquinovosylglycerol (SQGro).  Is a retaining glycoside hydrolase, since it forms the alpha anomer of SQ (PubMed:26878550).  Also exhibits some alpha-glucosidase activity against alpha-glucosyl fluoride in vitro, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed (PubMed:15294295).
What are the official names of this protein?
Sulfoquinovosidase, SQase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.