PharMolix/UniProtQA huggingface dataset:
Protein: DOHH_ASHGO
Sequence: MSTEFEKKMEEHIDSCSLEQLRDILVNKNGDAKLTNRFRALFNLKCVAEEFAQRPEEAQRAVEYICEAFADSSELLKHEVAYVLGQTGNLACAATLREVMLDHAQQCMVRHEASEALGALGDAASLGALERSRREDPSEEVRQTSELAIERIRWQASGAAATEQLQQSLYSSVDPAPPLSLEKDYDVPQLQALLNDQRAPLFERYRAMFRLRDIGSDEACYALASGFDDPSALFKHEIAYVFGQIGNPCVVPHLQEVLKREHEAPMVRHEAAEALGSIATDDVLPVLKRHLQDKDEVVRESAAIALDMYDYENSNELEYAPA
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GCH1_ACTP7
Sequence: MSIISAEAQKVREALIAKGIETPTVQLTKDKDSRRAEIQQHMRSVLELLGLDLQDDSLEETPHRLAKMYVDEIFSGLDYATFPKITNIENRMKVSEMVLVDDITLTSTCEHHFVTIDGKVAVAYYPKKWVIGLSKINRVVQFFAQRPQVQERFTEQILTAFQTILETDDVAVFVKATHFCVKCRGVKDTNSYTVTSAFGGVFLEDRETRKEFLGLINK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: ARGB_GRATL
Sequence: MLNNFERVQILSDALPFVQRFHGRTLVVKYGGSAMKNVYLKSKIIEDILFLSYIGIKVVIVHGGGPMINHWLKQVNIQPKFFNGIRVTDKDTMELVEMVLVGKVNKDLVTLLNRSSNLAVGLSGKDANLVVASSFFPDQKDNYTGKVQQVNIEIVNLLLSSGYIPVVASVASDLNGQAYNINADSVAGAIAECLNAEKLILLTDTPGIMSDINDPSSLIKYLNISQLEELKSQKIILGGMIPKVDCCIKALQGNVSSAHIIDGSVEHALLLEILTSAGIGSMLVL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HRCA_STAES
Sequence: MITKRQLSILNAIVEDYVDFGQPIGSKTLIHRHHLDVSPATIRNEMKQLEEMHFIEKTHTSSGRVPSESGIRYYVNRLLEQTSHQSQNKIQRLNQLLIENHYDSSTALTNFAHELSMKSQYATLVVRPNHKQDVINDIHLIRANNHLIILVMVFSSGHVENIHFVSHAQLNNINLNKIANFLTEHFSFNRKVLTQNIESYFSQKEELLLANEVVEMINLQIGNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNKITELLEDISTSQINVRIGKEIDDSLSDISIVTSQYHFDESLKGQIAVIGPTAMHYQNVIQLLNRIW
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: YICR_SALCH
Sequence: MDTLDELLPREKMLRSGIASLSDVELLALFLRTGTPGKDVMTLAKEILQHFGSLYGLLSADFAQFRGVNGIGLAKFAQLKGIAELARRYYSVRMNEESALLSPEMTREFLQSQLTGEEREIFLVIFLDAQHRVLQHSRLFSGTLNHVEVHPREIVREAIKLNASAVILAHNHPSGCAEPSKADKLITERVIKCCQFMDIRVLDHLIIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: LCST_PURLI
Sequence: MHIILTGTGLVGAIALDAMLQESSIDKITIISRKPVPQAEGQSKVEVIIQEDLSTYSDETLAKLKGAHGCIWTAGPPLMAVTRQEYEYGHIDLPVKAAKAFAALNDKFNFVYVSHDGCHDTRAVYIFDVKARAEEKLFQLHHDPSKRLEIKTKGGIEEQESLSSFVLYCIRPALIDYSTHDAIKPWLKPLPLAKKWTNGVILPLYRFLGLTSIMGTSQELGQAMKDLVISDGRDVDVAGASPEGRCLGAVGMRNWTQARNESPEDTVAV
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of the lipopeptide antibiotics leucinostatins that show extensive biological activities, including antimalarial, antiviral, antibacterial, antifungal, and antitumor activities, as well as phytotoxic (PubMed:27416025).  The function of lcsT within the leucinostatins biosynthesis has not been identified yet (Probable).
What are the official names of this protein?
Leucinostatins biosynthesis cluster protein T.
Protein: CSCL1_HUMAN
Sequence: MMDSPFLELWQSKAVSIREQLGLGDRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSCFLFLILVFSIIRRRFWDYGRIALVSEADSESRFQRLSSTSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTDNDLLWLHTIFAVIYLFLTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDARKETVESHFRDAYPTCEVVDVQLCYNVAKLIYLCKEKKKTEKSLTYYTNLQVKTGQRTLINPKPCGQFCCCEVLGCEWEDAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMATYILKDFNACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWLQWLGINFTLFLGLFFLTTPSIILSTMDKFNVTKPIHALNNPIISQFFPTLLLWSFSALLPSIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSEASIRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFQYEFGAMYAWMLCVFTVIVAYSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLEKGIHFAAVNQALAAPILCLFWLYFFSFLRLGMKAPATLFTFLVLLLTILVCLAHTCFGCFKHLSPLNYKTEEPASDKGSEAEAHMPPPFTPYVPRILNGLASERTALSPQQQQQQTYGAIHNISGTIPGQCLAQSATGSVAAAPQEA
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel (PubMed:30382938, PubMed:31587869).  Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion (PubMed:30382938, PubMed:31587869).
What are the official names of this protein?
CSC1-like protein 1, Transmembrane protein 63A.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: SPED_YERPP
Sequence: MSKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYIAYIDEQYNANRLTEILSETCSIIGANILNIARQDYDPQGASVTILVSEEPVDPRDVDTSEHPGPLPSAVVAHLDKSHICVHTYPESHPEAGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTMDYRVRGFTRDINGVKHFIDHKINSIQNFMSDDMKSLYHMMDVNVYQENIFHTKMMLKDFDLKHYLFNAKPEELSAEEKEQITRLLYKEMQEIYYGRNVPEV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: MSBA_PASMU
Sequence: MQDKDLSTVQTFKRLWPIISPFKLGLVVSGIALVINALADAGLISLLKPLLDEGFGKADVSFLRTMSYVVVLVIFLRGISNFISSYCLSWVSGKVVMIMRRRIFKHLMFMPVPFFDQNSSGRLLSRITYDSELVANSSSGALITIVREGAYIISLLAVMLYTSWQLSIVLFLIGPIIAVLIRFVSKRFRELSKNMQNSMGELTSTAEQMLKGHKVVLSFGGQIVEEERFNHVSNDMRRKGMKMAVADAISNPVVQIIASFALAAVLYLATVPTIMDQNLTAGSFTVVFSSMLAMMRPLKSLTNVNAQFQKGMAACQTLFALLDLETEKDLGTHKGENVQGYLSFKNVTFTYQSRDEPALRNLSFDVEKGKTVALVGRSGSGKSTIANLVTRFYDVDQGEITLDGINIQDYRLSSLRKNCAVVSQQVHLFNDTIANNIAYAAKDKYSREEIIKAAKDAYAMEFIEKLEHGLDTVIGENGVNLSGGQRQRLAIARALLRNSPVLILDEATSALDTESERSIQLALEKLQKERTVIVIAHRLSTIENADEILVIEHGEIKERGSHSELLALNGAYKQLHHIQVNH
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MOKI_MONPI
Sequence: MASHQSEKEKPQSCTTEVQVSHVTGLKLGLVVTSVTLVVFLMLLDMSIIVTAIPHITAQFHSLGDVGWYGSAYLLSSCALQPLAGKLYTLLTLKYTFLAFLGVFEVGSALCGAARCSTMLIVGRAVAGMGGSGLTNGAITILASAAPKQQQPLLIGIMMGLSQIAIVCGPLLGGAFTQHASWRWCFYINLPVGALAAILLLAIHIPKSVPTSDCTMPAPRAVGVRVILSQLDLLGFVLFAAFAVMISLALEWGGSDYMWDSSVIIGLFCGAGISLVVFGFWERYVGNSMAMIPFSVASRRQVWCSCLFLGFFSGALLTFSYYLPIYFQAVKDVSPTMSGVYMLPGIGGQIVMAIVSGAIIGKTGYYIPWALASGIIVSISAGLVSTFQPHTSIAAWVMYQFMGGFGRGCGMQTPIIAIQHALPPQMSALGISLAMFGQTFGGSLFLTLAKLVFSAGLDAGLREYAPAVSAEAVTAAGATGFRDVVPANLLSQVLLAYCKGIDHTFYLAVGASGATFLFAWGMGQVGLIWWGEERTGFGRDERV
What is the function of this protein?
Efflux pump; part of the gene cluster that mediates the biosynthesis of monakolin K, also known as lovastatin, and which acts as a potent competitive inhibitor of HMG-CoA reductase (PubMed:18578535, PubMed:19968298).
What are the official names of this protein?
Efflux pump mokI, Monacolin K biosynthesis protein I.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PCKA_VIBVU
Sequence: MTVMEHTKAASIDLTKHGLRNVKEVVRNPSYEMLFAEETRADLEGYEKGVVTELGAVAVDTGIFTGRSPKDKYIVKDATTEEHMWWTTPAVPNDNKPITQEVWNDLKQLVTNQLSGKRVFVIDGYCGANPDTRLSIRVITEVAWQAHFVKNMFIRPTEEELASFEPDFVVMNGAKCTNQKWKEHGLNSENFTVFNLTERMQLIGGTWYGGEMKKGMFAMMNYFLPLKGIASMHCSANMGKEGDVAIFFGLSGTGKTTLSTDPKRALIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPDIYNAIRRDALLENVTVRNDGSINFDDGSKTENTRVSYPIHHIENIVKPVSKGGHANKVIFLSADAFGVLPPVSKLTPEQTKYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLTLHPTKYAEVLVKRMEEAGAEAYLVNTGWNGSGKRISIQDTRGIIDAILDGSIEEAPTKHVPIFNLEVPTSLPGVDPTILDPRDTYVDPLQWESKAQDLAQRFINNFAKYTDNAEGQSLVAAGPQLD
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_STAA1
Sequence: MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATGDPTHITNIIKEWLNLSVNVERISVND
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PSBD_GOSHI
Sequence: MTIALGKFTKDENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TORL5_ARATH
Sequence: MPSVQIRSSPSHSQPAMTVTDLKQRVIACLNRLSDRDTLALAAAELDSIALNLSPETFSLFINCLQSTDSSAKSPVRKHCVSLLSVLSRSHGDSLAPHLSKMVSTVLRRLRDPDSSVRAACVAASVDMTTNITGQPFSILFGPMIETVIHDCDPNAQISAAMCLAAAVDAADEPDVEQLQKALPKIGKLLKSEGFKAKAELLGAIGTVIGAVGGRNSEKAVLDWLLPNVSEFLSSDDWRARKAAAEAMARVAMVEEELAPLYKKTCLGILESRRFDKVKLVRETMNRTLGLWKQLEGDSTEVSESSSSSKSASSGLSATSGKRSNTLKGKDRNLNTPLSSKSNDVEPLDRGDTPKDVEQEAVVSKEKRNRSTLGAKRVLFPAKMHKVKENGSNKSQVVQSSDEESPKTDSGSSSSSQAKSNAEELSLIRHQITQIEKQQSSLLDLFQKFMESSHNGMQSLERRVRGLETSFSVISTDLLVSRSITQNGNHKRNACRQN
What are the official names of this protein?
TORTIFOLIA1-like protein 5.
Protein: APHA_SALAR
Sequence: MKKITLALSAVCLLFTLNHSANALVSSPSTLNPGTNVAKLAEQAPVHWVSVAQIENSLTGRPPMAVGFDIDDTVLFSSPGFWRGKKTYSPNSDDYLKNPAFWEKMNNGWDEFSIPKEVARQLIDMHVRRGDSIYFVTGRSQTKTETVTNTLADNFHIPAANMNPVIFAGDKPGQNTKIQWLQEKNIRIFYGDSDNDITAARDCGIRGIRILRAANSTYKPLPQAGAFGEEVIVNSEY
What is the function of this protein?
Dephosphorylates several organic phosphate monoesters.  Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds (By similarity).
What are the official names of this protein?
Class B acid phosphatase, CBAP.
What is the protein family that this protein belongs to?
Belongs to the class B bacterial acid phosphatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ZNF23_HUMAN
Sequence: MLENYGNVASLGFPLLKPAVISQLEGGSELGGSSPLAAGTGLQGLQTDIQTDNDLTKEMYEGKENVSFELQRDFSQETDFSEASLLEKQQEVHSAGNIKKEKSNTIDGTVKDETSPVEECFFSQSSNSYQCHTITGEQPSGCTGLGKSISFDTKLVKHEIINSEERPFKCEELVEPFRCDSQLIQHQENNTEEKPYQCSECGKAFSINEKLIWHQRLHSGEKPFKCVECGKSFSYSSHYITHQTIHSGEKPYQCKMCGKAFSVNGSLSRHQRIHTGEKPYQCKECGNGFSCSSAYITHQRVHTGEKPYECNDCGKAFNVNAKLIQHQRIHTGEKPYECNECGKGFRCSSQLRQHQSIHTGEKPYQCKECGKGFNNNTKLIQHQRIHTGEKPYECTECGKAFSVKGKLIQHQRIHTGEKPYECNECGKAFRCNSQFRQHLRIHTGEKPYECNECGKAFSVNGKLMRHQRIHTGEKPFECNECGRCFTSKRNLLDHHRIHTGEKPYQCKECGKAFSINAKLTRHQRIHTGEKPFKCMECEKAFSCSSNYIVHQRIHTGEKPFQCKECGKAFHVNAHLIRHQRSHTGEKPFRCVECGKGFSFSSDYIIHQTVHTWKKPYMCSVCGKAFRFSFQLSQHQSVHSEGKS
What is the function of this protein?
May be involved in transcriptional regulation.  May have a role in embryonic development.
What are the official names of this protein?
Zinc finger protein 23, Zinc finger protein 359, Zinc finger protein 612, Zinc finger protein KOX16.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACTHR_MOUSE
Sequence: MKHIINSYEHTNDTARNNSDCPDVVLPEEIFFTISVIGILENLIVLLAVIKNKNLQSPMYFFICSLAISDMLGSLYKILENILIMFRNMGYLKPRGSFESTADDIIDCMFILSLLGSIFSLSVIAADRYITIFHALQYHSIVTMRRTIITLTIIWMFCTGSGITMVIFSHHIPTVLTFTSLFPLMLVFILCLYIHMFLLARSHARKISTLPRTNMKGAMTLTILLGVFIFCWAPFVLHVLLMTFCPNNPYCVCYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKRMLFCNRY
What is the function of this protein?
Receptor for corticotropin (ACTH).  This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP).
What are the official names of this protein?
Adrenocorticotropic hormone receptor, ACTH receptor, ACTH-R, Adrenocorticotropin receptor, Melanocortin receptor 2, MC2-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACPC_CAUVN
Sequence: MIRMDTVTDLSLREIGVAATKVLGRAVEVRAESHIGRDLAVDSLALMNIIMELEDTFDISIPLDRLASVETAGDLSKLINDLRTRA
What is the function of this protein?
Involved in de novo bacterial ceramide synthesis.
What are the official names of this protein?
Probable acyl carrier protein CCNA_01221.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
Protein: SYP_METMP
Sequence: MEFSEWYSDILEKAGIYDLRYPIKGCGVYLPYGFKIRRYSFEILRKLLDETGHDETLFPMLIPENLLAKEGEHIKGFEDEVFWVTHGGKTPLEVKLALRPTSETTMYYMMKQWIKVHTDLPLKLYQVVNTFRYETKHTRPLIRLREIMSFKEAHTAHATKKECDAQIEEALTLYKAFFDEIGVPYVISKRPEWDKFPGADYTMAFDTIYPDGKTMQIGTVHNLGQNFAKTFELEFETPDGEKDFVYQTCYGISDRAIASLISVHGDEKGLVIPVDVAPIQIVLIPLLFKGKEEIVMDKIKELNNTLKSEFRVHLDDRDIRPGRKYNDWELKGVPLRIELGPRDIENGHALIVRRDTGEKITVEYSNILEEVEKIVSMYKENLKLKAEEKVKSFITVLDFENDVNSLSEKVKAKLLENKGIILIPFNESIYNEEFEELIDASVLGLTTYEGKEYISVARTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_COXBU
Sequence: MVVIRLARGGSKKNPFYHIVVADRRKPRDGRFIERVGYYNPMARGQDIRLQLEKERISHWLNQGAQTSLRVKHLIKKLEKSPEEAQKGGMRKGEFKRLQAEQAAKAQKKAVATEEPKAEEAKEAPPAESQAAEGKEE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SDHB2_ORYSJ
Sequence: MILRRTLPRLASAKDGSGGGFADGHFPSLRGHPAARANARDAAEKQAALAAKEEEIRDHRRGDAAAASPAPSTVKEFRVYRWSPDAPSRRPHLQSYHVDLATCGPMVLDVLQKIKAEHDATLAFRRSCREGICGSCSMCIDGVNTVACLRPVDTDTSSATTVTPLPHMYVVRDLVVDLTSFYQQYKSVEPWLKRKTKTKTETTEHAQSPEERKRLDGLYECILCACCSAACPSYWWNAEAFLGPAALLHAYRWVSDSRDEYAAERVQALAEGWDKLYRCRMIKSCTATCPKSLDPAAAISAMKTLHQLGKP
What is the function of this protein?
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 2, mitochondrial, Iron-sulfur subunit of complex II, Ip.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL35_STRS2
Sequence: MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHLRKAGMVHAGDFKRIKSMLTGLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PYRE_STRMU
Sequence: MTLAKDIARDLLDIKAVYLKPEEPFTWASGIKSPIYTDNRITLSYPETRTLIENGFVETIKEAFPEVEVIAGTATAGIPHGAIIADKMNLPFAYIRSKPKDHGAGNQIEGRVTKGQKMVIIEDLISTGGSVLDAVAAAQREGADVLGVVAIFTYELPKATANFEKASVKLVTLSNYSELIKVAKVQGYIDADGLTLLKKFKENQETWQD
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: SP3_MOUSE
Sequence: MTAPEKPVKQEEMAALDVDGGGGGGGHGEYLQQQQQQQQQHGNGAAAAAAQDTQPSPLALLAATCSKIGPPSPGDDDEEAAVAAAAGVPAAAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPGAATSSGQYVLPLQNLQNQQIFSVAPGSDSSNGTVSNVQYQVIPQIQSTDAQQVQIGFTGSSDNGGINQENSQIQIIPGSNQTLLASGTPPANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVPLGLPGNITFVPINSVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDVNETNADTDLFVPTSSSSQLPVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQDSQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGALTSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKKVIHSSSTVLASVEAGRDDALITAGGTTLILANIQQGSVSGIGTVNTSATSNQDILTNTEIPLQLVTVSGNETME
What is the function of this protein?
Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications.  Binds to GT and GC boxes promoter elements.  Competes with SP1 for the GC-box promoters.  Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping (By similarity).
What are the official names of this protein?
Transcription factor Sp3.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Note=Localizes to the nuclear periphery and in nuclear dots when sumoylated. Some localization in PML nuclear bodies (By similarity).
Protein: CYB_SORRA
Sequence: MTNLRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGICLIIQILTGLFLAMHYTSDTXTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLPSDADKIPFHPYYTIKDILGVLLLILALTSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALALSILILAVVPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVIMPITSLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: B4GN2_HUMAN
Sequence: MGSAGFSVGKFHVEVASRGRECVSGTPECGNRLGSAGFGALCLELRGADPAWGPFAAHGRSRRQGSRFLWLLKILVIILVLGIVGFMFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMPLHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLKFILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIATKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSENGACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLGTLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA
What is the function of this protein?
Involved in the synthesis of the Sd(a) antigen (Sia-alpha2,3-[GalNAc-beta1,4]Gal-beta1,4-GlcNAc), a carbohydrate determinant expressed on erythrocytes, the colonic mucosa and other tissues.  Transfers a beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain.
What are the official names of this protein?
Beta-1,4 N-acetylgalactosaminyltransferase 2, Sd(a) beta-1,4-GalNAc transferase, UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: THIE_STAAW
Sequence: MFNQSYLNVYFICGTSDVPSHRTIHEVLEAALKAGITLFQFREKGESALKGNDKLVLAKELQHLCHQYDVPFIVNDDVSLAKEINADGIHVGQDDAKVKEIAQYFTDKIIGLSISDLDEYAKSDLTHVDYIGVGPIYPTPSKHDAHIPVGPEMIATFKEMNPQLPIVAIGGINTNNVAPIVEAGANGISVISAISKSENIENTVNRFKDFFNN
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.