PharMolix/UniProtQA huggingface dataset:
Protein: MAK1_CAEEL
Sequence: MMFEYEEDEDPMEQQKHEEFKHHSTDHSGSPQENPFRFSYDTGKRAASMFVTPSSEDLIAYGTKHLLDSPTAVQRSLVLNATTSLNIDCDLSSDDDLSPTTQRKICFCASQNPAETQEQGLRPAKSTLAISFPCHQHQITEDYTISAEIIGIGESGKVMACYQKVTGEKFALKVLRDSQKARREVELHWLTNAHENVVSILDIYENTFDNVKCLLMVVEFLEGGDLLSQFESQGSIPYTEKKVGEIIRQIGNAVMYLHDMNIAHRDIKLENILCSGTGDNCVYKLGDYGFAKRPERNVLMESPCCTPFYAPPEVLGRERYDKSCDMWSLGVAMYILLCGYPPFYSMKGVALSPGMRSRIANAYYAFPHEEWDCVSKDTKDDIRCLLRTNPSDRLTIHELMATPLVTGEPIVPGKHITTAIAIPGADESECGGGVFDDGFIVEEEETPDTVAEILPVPKSVRFLRDGVKAPRLHSIQEEVGRAMEIMRMGTDQVYIKNPTASCNNLFERRRAVHLSIPRVYC
What is the function of this protein?
Serine/threonine-protein kinase which may play a role in body wall muscle contraction.  May phosphorylate unc-22/twitchin.
What are the official names of this protein?
MAP kinase-activated protein kinase mak-1, MAPK-activated protein kinase mak-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere. Cytoplasm, myofibril, sarcomere, A band. Note=Localizes between and around dense bodies. Colocalizes with myosin heavy chain unc-54 at the outer edge of A-bands.
Protein: RIMK_SALG2
Sequence: MKIAILSRDGTLYSCKRLREAAMRRGHLVEILDPLSCYMNINPAASSIHYKGRRLPHFDAVIPRIGSAITFYGTAALRQFELLGSYPLNESVAITRARDKLRSLQLLARQGIDLPITGIAHSPDDTSDLIKMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIAEAKGCDIRCLVVGNEVVAAIERCAKAGDFRSNLHRGGVASIATITPRERDIAIKAAQTLGLDVAGVDILRAARGPLVMEVNASPGLEGIEKTTGVDIAGRMIQWIERHATPEFCLKIGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: Y142_LEUMC
Sequence: MSKKVVSTTTAPKALGPYSQAILNDNTLYISGQIGIDPETDEFAGATTAEQAHQIFDNIDNILHEAEFSRNDIVKAALFFDDIADFALVNDIYAQYFDTTSVEEFPARSAVQVAALPKNAKLEIEITAMK
What are the official names of this protein?
RutC family protein in leuC 5'region.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: HCAR2_HUMAN
Sequence: MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGPTSP
What is the function of this protein?
Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase.  This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.  Mediates nicotinic acid-induced apoptosis in mature neutrophils.  Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.  The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide.
What are the official names of this protein?
Hydroxycarboxylic acid receptor 2, G-protein coupled receptor 109A, G-protein coupled receptor HM74A, Niacin receptor 1, Nicotinic acid receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IAA2_SAUCO
Sequence: SWCDPATIKYVSGLTGCRAMVKLECLGSQ
What is the function of this protein?
Alpha-amylase inhibitor.
What are the official names of this protein?
Alpha-amylase inhibitor 2.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I6 (cereal trypsin/alpha-amylase inhibitor) family.
Protein: IOLG_CERS1
Sequence: MTLRIGIIGTGAIGTDHARRINRVLSGAEVTAVTDVNRDNAEACVAGVAPGAQILGSAEEVIAASDAVLVCSWGAAHEAQVLAAIAAGKPCFCEKPLATEAYGARRIVEAEGAMGRRLVQVGFMRRYDRGYIALKETVRTRLGPPLMIHAAHRNPTVPGRYRTPMAIHDTLIHEIDVLRWLLDDEYVSAQVIFPRATRHTHAGLRDPQIVLLETAKGVRIDVEIFVNCRYGYDIQCEVVGEEGTARLPEPMAIPTRLGAMFGQPILMDWKDRFIDSYDVELQDFLKAAAQGTAAGPSAWDGYAAAITADVCVQAQERPGAILPVTLPARPALYA
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: IF2G_PYRHO
Sequence: MGERRKTRQAEVNIGMVGHVDHGKTTLTKALTGVWTDTHSEELRRGITIKIGFADAEIRRCPNCGRYSTSPVCPYCGHETEFVRRVSFIDAPGHEALMTTMLAGASLMDGAILVIAANEPCPRPQTREHLMALQIIGQKNIIIAQNKIELVDKEKALENYRQIKEFIKGTVAENAPIIPISALHGANIDVLVKAIEDFIPTPKRDPNKPPKMLVLRSFDVNKPGTPPEKLVGGVLGGSIVQGKLKVGDEIEIRPGIPYEEHGRIRYEPITTEIVSLQAGGQFVEEAYPGGLVGVGTKLDPYLTKGDLMAGNVVGKPGKLPPVWDSLRLEVHLLERVVGTEQELRVEPIKRKEVLLLNVGTARTMGLVTNLGKDEIEVKLQIPVCAEPGDRVAISRQIGSRWRLIGYGIIKE
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit gamma, aIF2-gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: YHBQ_ECO5E
Sequence: MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAGFAKLLSSLQTPEIKSD
What are the official names of this protein?
UPF0213 protein YhbQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: VATB_METMJ
Sequence: MKEYRTVAQIAGPLVFVEKTEPVGYSELVNIVTADGTVKRGQVLDTSDEIVVVQVFETTAGIGRDSGIRFTGETIKMPVGKDMLGRILSGGGKPIDGGPDIVPEKRLEITGAAINPYARSSPEDFIQTGISTIDGTNTLVRGQKLPIFSASGLPHNDVALQIARQAKVPGSTEEFAVVFAAMGITREEANYFMADFEKTGALERSVVFLNLADDPAVERTITPRLALTTAEYLAFDLGYHVLVILTDMTNYCEALRQIGAAREEVPGRRGYPGYMYTDLASIYERAGIIKGVKGSVTQIPILTMPGDDITHPIPDLTGYITEGQIVVNRELHRKGIYPPINVLPSLSRLMNLGIGEGHTREDHKKVSDQLYAAYAEGNDLRGLVAIVGKDALSERDRMFLEFADLFEDRFVRQGLYEDRSIEETLDLGWELLSTLPEEQLVRIDRELIQKYHPKYRKKAQG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: O51E2_RAT
Sequence: MSSCNFTHATFMLIGIPGLEEAHFWFGFPLLSMYAVALFGNCIVVFIVRTERSLHAPMYLFLCMLAAIDLALSTSTMPKILALFWFDSREITFDACLAQMFFIHALSAIESTILLAMAFDRYVAICHPLRHAAVLNNTVTVQIGMVALVRGSLFFFPLPLLIKRLAFCHSNVLSHSYCVHQDVMKLAYTDTLPNVVYGLTAILLVMGVDVMFISLSYFLIIRAVLQLPSKSERAKAFGTCVSHIGVVLAFYVPLIGLSVVHRFGNSLDPIVHVLMGDVYLLLPPVINPIIYGAKTKQIRTRVLAMFKISCDKDIEAGGNT
What is the function of this protein?
Olfactory receptor.  The activity of this receptor is probably mediated by G-proteins wich induce elevation of intracellular Ca(2+), cAMP and activation of phosphorylation of the protein kinases PKA and MAPK3/MAPK1.  Activation of OR51E2 may affect melanocyte proliferation, differentiation, and melanogenesis and may increase proliferation and migration of primary retinal pigment epithelial (RPE) cells.  Activated by the short chain fatty acids (SCFA), acetate and propionate.  In response to SCFA, may positively regulate renin secretion and increase blood pressure (By similarity).  May also be activated by steroid hormones and regulate cell proliferation (By similarity).  Activated by L-lactate in glomus cells (By similarity).
What are the official names of this protein?
Olfactory receptor 51E2, G-protein coupled receptor RA1c, Olfactory receptor 59.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Protein: EFPL_YERPS
Sequence: MAKANEIKRGMAVNLNGKLLLVKDIDVQSPSARGASTLYKMRFSDVRTGLKVEERFKGDENLDTITLTRRAVNFSYIDGDEYVFMDDEDYTPYNFKKEQIEDELLFIPEGGMPGMQVLTMEGQLLALELPQTVDMEIVDTAPSIKGASASARNKPAIMSTGLSIQVPEYISPGEKIRIHIAERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: Y206_ENCCU
Sequence: MGMWLVWIFALDNILCASKEEEKKCELPRRLGEMNIKEITEKVEIDGLDTKIIIPFIFHDAKPVVSPITRYRDISQEERRYVEEIIKGLPKLVWDSMVWIYVPGYTWWIKSLMDNVFNATSFEGFNPVDLYKKAKGKSEIRFADLVMSIFRFNGRIVNRFGQRLVREVEVKIKEMSNEMPSSEKKEKEERLNQILEYGKKLCTREKQEEMLKAQKIVCDACVYLWEKGSEDRVAITIMVYLRNLEVQMIRSSMKKVKVGEPLTFYMNHEVLISAYKEYKIGVAGELVKQVLKNDKDIDSESVNRVVCSIREREEDERKRAEAESARNREELLRMEEREKGKEKGSKGKGRKKRGKKGAGEAKEESKEEDRGGEEEESVEADVPVEEMAVGGARPKKKSPKEESKGEERCYKVHKRVLRWMKSAERIKYELDNGEEEKWRGRSIEEIEEQKALHDIIEVLKLLRSKECDKFFVRTGKYMKGGSERWNMVGVGILEEGGKKRVGNVEVGLFEGKGGENIIYHLMFKPTDFEEEGEGARPSFGRCDGVDAIEEGRISDMSGFQYPPGVRSEITSSGSEFRIVWKNQRDTSLVLRSLTVLRIPEIR
What are the official names of this protein?
UPF0329 protein ECU02_0060.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: SPCS1_PIG
Sequence: MLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYVAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQDSGTEDKKPGERKIKRHAKNN
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Dispensable for SPC enzymatic activity (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 1, Microsomal signal peptidase 12 kDa subunit, SPase 12 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GBB4_HUMAN
Sequence: MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-4, Transducin beta chain 4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
Protein: LIPC_BACSU
Sequence: MVLRYTALGDSLTTGRGSGLFSPGFVQRFGDMMEADLKTRTAINIFARSGLNTEEILGLLSYPYVQKCIRDADMITITGCGNDLIDSVLAYQTSKDETIFSRVSAHCHENFEKMIAKVAEIKGENPSPYAIRVFNLYNPFPEIDIAGKWITSFNSHLETLASAPHVKIADAYSIFKGKEQEYLSFDGVHPNSKGYQAMAEAVHKLGYKELSVS
What is the function of this protein?
Lipase involved in spore germination.
What are the official names of this protein?
Spore germination lipase LipC.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Spore coat.
Protein: BUD3_ASHGO
Sequence: MLTAKQDEVGRELRVATGTSLIEYPVKDWLLRRQPTEWEALLGEAAIFSGQDELLWGPFVACVYREPRTTRLNCLFMDRIGVMHLHSVDVSDTSRFYPAVENLRPEYRTQVVRRCLAVGLLKKYVLLDPSAVRLIRAELPYDYDQTTAGDLANTCELVEGQAARDVGQLLVRLGLVQPRHVRSLMLDVVYENHADVVDANNKLVYYLGEQLEQLFDPLTEYSPEPTELSYRVPDQVRTSLSDEMPLMVSICEELLQLQTNFTLSLVGFLQKFLIPLRIKALNEQVPGLSTVKLNNIFPPTIDEVTRINCIFLDALKAALPYGSLEVLKACSITAPYFYKAYTRHEAATKFFSRDIKSFLSTFGKSLSDLNFYSEIKLDTLIHGPQEKLTKLKLIIDRLFDSKDWETNEEQKEADRCYRSICDVIDSFGKDEPPNTYDTRVFTPSGKILTELAKGWPAELQYKWLKRRVVGVFDVISVTDPESRDIVVIFSDYIVFLHVINGNLYYSGDSKKPLISDVLMNSLINEVPLPPKIPKLEVLSHSYIDDVVVSTYGKNSLRFDTLNAERPSSVAYTLASSSVEASYVADLCTKARILEKDTAFHLFKTAIDSFHVYSTAHESEAYKTERIKSPFVLFLNIPDSIGALQDHNATVGLFASLNKNDKVTLVRLGLDGSREESFASLDNFLSLIIEELLIFYPSYLSSATSPLFQQLMQINEQLVQTLLDPKGVHSASKSKCALRTSKKKKMPANLVSTNDNSRTLSPGTIISRTPRTISTITPKQEKRKSVGQASNSPARGSISTTPRKHKRESILGKISGLFHKKDKKENKRNSVGSDTRNRHDNGSVHILRNSSSSFRELESPRQMKRFSSVVHTAVPSSSKRRTSGISPSKGTVNLRALQDAENDDNADISKIPIPEGESLFDDTIRVDGVDADFYAQKDRLSKIYNHDLYGEVVPSAPGSKNVNVVSGATREQEKQQNTQKAIARELLASVDQQKRQPTHSAPAESQIVIPGLPQSNVPQINFGRSPSFIELFGGMRLVLDENDESVNWRRLCSERSLNEKYQIRPATYAGCISGELAPPVGIISDQRDSNLSGDNDADTPLPMHSSNKSILSDETLEKGEFERDFAISTPKSQTVSDVNARRETWGYSHSHDEEIDSEKRANTKPVSAPAPNVIPGLIITANSPTKPWHKENTRIKVSDVRSEGTDVSYISSLKKSSNRLVELSVNSQEDFEDERHTPVIEPIQNPEAPSLIENTETAPVASNSSNEETLSKLLGSQGVIDLTEETIDYSSINRKHASIQTAYPVLDDVEFSTFHMSFGDMKAEDSHLANQRESYLFSNSTIAGKKDESHGPVFYKLPDFVADDSYLGYSAVDQHAKHERNTEIGEEDEAMWVSPSKLDIFDLSKQPESVYKRTSIPAKHAELLSKMRKDGSVKFEESMFIRDNSYVYLGQFLSADEVIEQQDKKLAANTDEMDSARRL
What is the function of this protein?
Required for proper septum positioning and septum construction during septation.  Acts as a landmark to mark sites for future septation, and as part of a scaffold that recruits components of the contractile ring to the site of septation.  Not required to determine the site of lateral branch formation.
What are the official names of this protein?
Bud site selection protein 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the BUD3 family.
What are the subcellular locations of this protein?
Cell tip. Cell septum. Note=Localizes close to the hyphal tip and transiently localizes to septal sites. Initially forms a single ring which subsequently splits into two distinct rings as the septum forms, and disappears after septum completion.
Protein: DPOL_PYRWO
Sequence: MILDVDYITEEGKPVIRLFKKENGKFKIEHDRTFRPYIYALLRDDSKIEEVKKITGERHGKIVRIVDVEKVEKKFLGKPITVWKLYLEHPQDVPTIREKVREHPAVVDIFEYDIPFAKRYLIDKGLIPMEGEEELKILAFDIETLYHEGEEFGKGPIIMISYADENEAKVITWKNIDLPYVEVVSSEREMIKRFLRIIREKDPDIIVTYNGDSFDFPYLAKRAEKLGIKLTIGRDGSEPKMQRIGDMTAVEVKGRIHFDLYHVITRTINLPTYTLEAVYEAIFGKPKEKVYADEIAKAWESGENLERVAKYSMEDAKATYELGKEFLPMEIQLSRLVGQPLWDVSRSSTGNLVEWFLLRKAYERNEVAPNKPSEEEYQRRLRESYTGGFVKEPEKGLWENIVYLDFRALYPSIIITHNVSPDTLNLEGCKNYDIAPQVGHKFCKDIPGFIPSLLGHLLEERQKIKTKMKETQDPIEKILLDYRQKAIKLLANSFYGYYGYAKARWYCKECAESVTAWGRKYIELVWKELEEKFGFKVLYIDTDGLYATIPGGESEEIKKKALEFVKYINSKLPGLLELEYEGFYKRGFFVTKKRYAVIDEEGKVITRGLEIVRRDWSEIAKETQARVLETILKHGDVEEAVRIVKEVIQKLANYEIPPEKLAIYEQITRPLHEYKAIGPHVAVAKKLAAKGVKIKPGMVIGYIVLRGDGPISNRAILAEEYDPKKHKYDAEYYIENQVLPAVLRILEGFGYRKEDLRYQKTRQVGLTSWLNIKKS
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase, Pwo polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: EIF3M_DROPS
Sequence: MTSHPVFIDLSLDEQVQELRKYFKKLGAEISSEKSNKGVEDDLHKIIGVCDVCFKDGEPSQIDGILNSIVSIMITIPLDRGENIVLAYCEKMTKAPNQPLGKVCLQSLWRLFNNLDTASPLRYHVYYHLVQVAKQCEQVLEVFTGVDQLKTQFANCPPSSEQMQKLYRLLHDVTKDTNMELSSKVMIELLGTYTADNACVAREDAMKCIVTALADPNTFLLDPLLALKPVRFLEGDLIHDLLSIFVSDKLPSYVQFYEDHKEFVNSQGLNHEQNMKKMRLLTFMQLAESNPEMTFDTLTKELQITEDEVEPFVIQVLKTKLVRARLDQANRKVHISSTMHRTFGAPQWEQLRDLLQAWKENLSSVRDGLTNVSSAQLELARTQKLIH
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m, Transport and Golgi organization protein 7, Tango-7.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: FADB_PSEPG
Sequence: MIYEGKAITVKALESGIVELKFDLKGESVNKFNRLTLNELRQAVEAIQADASVKGVIVSSGKDVFIVGADITEFVDNFKLPEAELVAGNLEANRIFNAFEDLEVPTVAAINGIALGGGLEMCLAADYRVMSNSAKIGLPEVKLGIYPGFGGTVRLPRLIGSDNAIEWIAAGKENRAEDALKVGAVDAVVAPELLLAGALDLIKRAISGELDYKAKRQPKLEKLKLNAIEQMMAFETAKGFVAGQAGPNYPAPVEAIKSIQKAANFGRDKALEVEAAGFAKLAKTSVAESLIGLFLNDQELKRKAKAHDEIAHDVKQAAVLGAGIMGGGIAYQSAVKGTPILMKDIREEAIQLGLNEASKLLGNRVEKGRLTPAKMAEALNAIRPTLSYGDFANVDIVVEAVVENPKVKQAVLAEVEGQVKDDAILASNTSTISINLLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEKSSEVAVATTVAYAKKMGKNPIVVNDCPGFLVNRVLFPYFGGFAKLVSAGVDFVRIDKVMEKFGWPMGPAYLMDVVGIDTGHHGRDVMAEGFPDRMKDERRSAVDALYEANRLGQKNGKGFYAYETDKRGKPKKVFDATVLDVLKPIVFEQREVTDEDIINWMMVPLCLETVRCLEDGIVETAAEADMGLVYGIGFPPFRGGALRYIDSIGVAEFVALADQYADLGPLYHPTAKLREMAKNGQRFFN
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: BDS3_ANTEL
Sequence: GTPCYCGKTIGIYWFGTKTCPSNRGYTGSCGYFLGICCYPVD
What is the function of this protein?
Binds to voltage-gated sodium channels (Nav), and slows down the inactivation of mammalian Nav1. 2/SCN2A, Nav1. 3/SCN3A Nav1. 4/SCN4A, Nav1. 6/SCN8A, insect DmNav1 and BgNav1 channels, and arachnid VdNav1 channel (PubMed:22972919).  This toxin acts by binding to site 3 of sodium channels.
What are the official names of this protein?
Delta-actitoxin-Ael2d, Delta-AITX-Ael2d, Toxin APETx3.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: ATPH_HORVU
Sequence: MNPLIAAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FPG_LATSS
Sequence: MPELPEVENVRRGLETLAVGKTVSAIDIRWSKIIVNPDEVFTAGLVGQQITAVDRRGKYLLIRFGEQLTVVSHLRMEGKYEVVAKEAPISKHTHVIFEFTDGQQMRYLDTRKFGRMQLIETGQENTVAGLKDLGPEPTPTTFLKADFYQRLQKHHKAIKPLLLDQKVVTGLGNIYVDETLWLSHIHPETPANDLTRAETDRLHDEIIAELELAINHGGTTVNTFLNATGHAGAFQEMLHVYGKKGVPCERCGTPIEKIKVAQRGTHFCPKCQIKRNAK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: GAG_MLVHO
Sequence: MGQTITTPLSLTLDHWRDVQRIASNQSVDVKKRRWVTFCSAEWPTFNVGWPQDGTFNKDIITQVKIKVFSPGPHGHPDQVPYIVTWEAIAYDPPPWAKPFVHPQLSVSPSAPSAFSHEVSGPPTRSSLYPALTPTKSPSPKTQVLSDDGGPLIDLLSDDPPPYRGPENQPPAGRPTTTMQEMPRLPLKVPQEPSPMASRLRGRREHPAADSTTSQAFPLRTGGNGQLQYWPFSSADLYNWKNNNPSFSEDPGKLTALIESVLITHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEINDAFPLERPDWDYTTPAGRNHLVLYRQLLLAGLQHAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPDIGRKLERLEDLKSKTLGDLVREAERIFNKRETPEEREERIRRETEEKEERRRAENEQREKERDRRRHREMSKLLATVVSGQRQDRQGGERRRPQLDKDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLDD
What is the function of this protein?
Involved in the packaging and encapsidation of two copies of the genome.  Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome.  This binding is dependent on genome dimerization.
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. Host late endosome membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p30]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p10]: Virion.
Protein: PLCD1_RAT
Sequence: MDSGRDFLTLHGLQDDPDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMRSPESQLFSIEDIQEVRMGHRTEGLEKFARDIPEDRCFSIVFKDQRNTLDLIAPSPADAQHWVQGLRKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQTDSLEDEEIETFYKMLTQRAEIDRAFEEAAGSAETLSVERLVTFLQHQQREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMDQPLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQRVMARHLRAILGPILLDQPLDGVTTSLPSPEQLKGKILLKGKKLGGLLPAGGENGSEATDVSDEVEAAEMEDEAVRSQVQHKPKEDKLKLVPELSDMIIYCKSVHFGGFSSPGTSGQAFYEMASFSESRALRLLQESGNGFVRHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCGYVLKPAFLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEIHGVGRDTGSRQTAVITNNGFNPRWDMEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQSTIPWNSLKQGYRHVHLLSKNGDQHPSATLFVKISIQD
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (PubMed:16000311).  Essential for trophoblast and placental development (By similarity).  Binds phosphatidylinositol 4,5-bisphosphate (By similarity).
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1, Phosphoinositide phospholipase C-delta-1, Phospholipase C-III, PLC-III, Phospholipase C-delta-1, PLC-delta-1.