PharMolix/UniProtQA huggingface dataset:
Protein: CCD62_MOUSE
Sequence: MRSSEGAPSWAVALPPPLRPCAYGVSEVTRCWHQLSLGAGESSMNPSATLYRRQNIGSEVETSTIEKQRKELQLLIGELKDRDKELNDMVAVHQRQLLSWEEDRQKVLTLEERCSKLEGELHKRTDIIKSLMKKVKTLESNQAECQTALQKTQQQLQEMAQKATHSTLLSEDLEARNENLSSTLVDLSAQVGQLQAREQALTTMIKLKDKDIIEAVNHISDCSGKFKLLEHALRDAKMAETCVVREKQDYKQKLKALRIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELIFTVEREKRKDELLDIAKSKQDRTNSELQNLRQIYVKQQSDLQFLNFNIESSQELIQIHGLKMEEPKALECSKDMCLSDLDNNYPKIDIKRERNQKSLVKDQTFEVMLAQHNGSDKSSCDACREKKLQVNTALGEKSVIALSSLFTKDLLDKQKSWSLGGKIQTEPENKVTLCKVHAKSPKCDGVGLPTEEKQLSETSVSLSDEKQWHDINVYLGLSSCSKQPDRLDGDGHDRTGTSEVSCCTPNVVCIGDNDLSESKCCHPSNIIIEAPGHMTDTEWMNIFKPSRAQRIVRHKTMCTCSRSVSAMKYNSSASELIGMQPSQCVGSLKSAEREEESAALPDRRTSANEKDDFSPTSKLQRLLAESRQMVTDLELSTLLPISCENLNRSKLEVSEEPDEKTTLVSH
What is the function of this protein?
Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation.  Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR (By similarity).  Required for normal spermiogenesis (PubMed:28339613).  It probably plays a role in acrosome formation (PubMed:28339613).
What are the official names of this protein?
Coiled-coil domain-containing protein 62.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly nuclear.
Protein: PUR9_COLP3
Sequence: MDTPRPIKRALLSVSDKAGIVEFAQRLSEKGVDLLSTGGTAKLLAENGIKVTEVSDYTGHPEIMDGRVKTLHPKVHGGILARRGIDEVVMDENGISAIDMVVVNLYPFANAVSDENCSLENAIENIDIGGPTMVRAAAKNHKDVTIVVNASDYERVLTELDNNNDSLTYKTRFDLAIAAYEHTASYDGMIANYFGKMLPAYGETESKASLENKVKFPRTFNSQFIKTQDLRYGENSHQDAAFYKEENPEEASVSTATQLQGKALSYNNIADTDAALECVKEFDEPACVIVKHANPCGVAIGDDILAAYEGAYKTDPTSAFGGIIAFNRELDADTAEAIVSRQFVEVIIAPSVSDAAAQIVAAKPNLRLLECGQWDNKTTGFDFKRVNGGLLVQDTDQGRVTSDDLTVVTKRQPTDEEMRDLQFCWKVAKFVKSNAIVYVKNSSTIGVGAGQMSRVYSAKVAGIKAADENLEVKGSVMASDAFFPFRDGLDAAAEAGITAVIQPGGSMRDDEVIAAADEHNIAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: DNLJ_VESOH
Sequence: MLSQNIIDKIIRQDILVDELLDEELSIFCQTANLAYRSGKPIISNEDYDFIYLATLKNKEPNNPLFKSIEPEGRAFAEEKVLLPELMLSIDKAYSWNEMSKWIERLEKSGMLIGLDLNAIQIKATPKLDGFAGFDDGNRLYTRGDGKKGSDISRVFKRGLCVFKDSGRGLGAGEIVVKKSYFEKYLVHSFEYPRNFQSSLIKEKALDEQAQKAIIDKGALFVPFIKLPIWSGSMTELVAKFEEIVSQVLVMVDFDVDGVVFEVINIDLKTQMGANRKFHRWQIAFKENKDIVQVKVLNVMPQVGRSGKITPVAEVEPTLLSGATIVRVTGHHYGLVKEQGLGIGSVVELTRSGLVIPKIISVLKPMPVDIPDNCLSCGMPLVWESDFLVCVNHKNCPAQIIGRITYFFKVLANNDGFGIATVEKLYAHNIRSVSQIYTLNVERLMAIGFGEKTSINLISQLSRSISEKIEDWRFLAAFGMHRMGLGNCENLLKSYRLNDIFDLTLEQITNIDGFAELTAQVIVQGLVSIVDEYNQIYQYNFNLDTTVFTKDLQTLMHELFDKRIVFTGKMNCPRNEMKKHAKLVGIKVSTTISTKIDYLVIGSRVGQKKIQNAEKLGVVVMTEADYLSKITM
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RNH_NOVAD
Sequence: MKHVEIFTDGACKGNPGKGGWGALLRMGEHEKEMAGSEKETTNNRMELMAAIRALEALKQPCRVTLHTDSKYVLDGITKWIFGWQKKGWKTADNKPVKNEDLWRALVDAVRPHKVEWVWVKGHDGHPENERVDKLASDAALAA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_RICCN
Sequence: MSNSSKKHLDLPYRPGVGMMILNANNHIFVGKRIDTKISAWQMPQGGIVPGETPSIAAMREMLEEIGSDKGYIIAESKFWYSYDVPSFLIPKLWNGNFRGQKQRWFLIRFTGNNEDININTSNPEFDQWRWASLDELLSIIIPFKRKLYQAVVKEFESLIQ
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: MURA_THEYD
Sequence: MDKLLIFGGLPLKGEVTISGAKNAALPIMASTLLAQGVHIFKRIPKLRDVFTMTELIKRMGGIVEFNELCKINTIKINKFEASYDLVKTMRASILVLGPLVARFGRAKVSLPGGCAIGARPVNLHINGLQKMGAKISLQEGYIIAKASRLMGTKIYFDIPTVTGTENLMMAATLAKGTTIIENAAKEPEIVDLANYLILMGAKIEGAGTSIIKVEGVDELKPPQEYEIIPDRIETGTFIAIAGACGGDISLKGCRIDHIDAIILKMKDAGISFKEIENGIRVIGPKRLQAVDIKTMPYPGFPTDMQAQFMAMMTVANGTSVIKETIFENRFMHVAELRRMGADITVEGNTATIRGVKKLKGAPVMATDLRASASLVIAGLIAEEETLIDRIYHLDRGYEELDKKLIQLGARIQRIK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_HELPH
Sequence: MKKERTESLVAQALKNIGNDRYMLDNLVFARVKQLNAGAKTLVNMDPKRHKLVDIAIREIAEGKIDIDRIDERN
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PG087_VACCW
Sequence: MPFRDLILFNLSKFLLTEDEESLEIVSSLCRGFEISYDDLITYFPDRKYHKYISKVFEHVDLSEELSMEFHDTTLRDLVYLRLYKYSKCIRPCYKLGDNLKGIVVIKDRNIYIREANDDLIEYLLKEYTPQIYTYSNERVPITGSKLILCGFSQVTFMAYTTSHITTNKKVDVLVSKKCIDELVDPINYQILQNLFDKGSGTINKILRKIFYSVTGGQTP
What is the function of this protein?
Involved in postreplicative transcription elongation on intermediate and late genes.
What are the official names of this protein?
Late transcription elongation factor OPG087, Late transcription elongation factor G2, Protein G2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG087 family.
Protein: FLGM_BACSU
Sequence: MKINQFGTQSVNPYQKNYDKQAVQKTVAQPQDKIEISSQAKEMQHASDAVTGSRQEKIAQLKAQIENGSYKVDANHIAKNMINFYKKQ
What is the function of this protein?
Allows the coupling of early and late flagellar synthesis through the repression of RNA polymerase sigma-D factor-dependent transcription.
What are the official names of this protein?
Negative regulator of flagellin synthesis, Anti-sigma-D factor.
What is the protein family that this protein belongs to?
Belongs to the FlgM family.
Protein: Y3216_YERPS
Sequence: MSAVLSTENGLILKLYIQPKASRDQIVGLHGDELKVAITAPPVDGQANAHLVKFIAKQFRVAKSQVIIEKGELGRHKQIKVINPQQIPPEVTILLK
What are the official names of this protein?
UPF0235 protein YPTB3216.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: SET1B_HUMAN
Sequence: MENSHPPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHHKLYRYDGQHFSLAMSSNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLRDMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKDAVQHLHSTSVMGNIIHVELDTKGETRMRFYELLVTGRYTPQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSASSSSSASSSSGSSTTSPSSSASDKEEEQESTEEEEEAEEEEEEEVPRSQLSSSSTSSTSDKDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPSTSLSSAKKKKRDDGIREHVTGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRGTLN
What is the function of this protein?
Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism (PubMed:25561738, PubMed:17355966).  Part of chromatin remodeling machinery, forms H3K4me1, H3K4me2 and H3K4me3 methylation marks at active chromatin sites where transcription and DNA repair take place (PubMed:25561738, PubMed:17355966).  Plays an essential role in regulating the transcriptional programming of multipotent hematopoietic progenitor cells and lymphoid lineage specification during hematopoiesis (By similarity).
What are the official names of this protein?
Histone-lysine N-methyltransferase SETD1B, Lysine N-methyltransferase 2G, SET domain-containing protein 1B, hSET1B.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Chromosome. Note=Localizes to a largely non-overlapping set of euchromatic nuclear speckles with SETD1A, suggesting that SETD1A and SET1B each bind to a unique set of target genes.
Protein: YEAH_ECO55
Sequence: MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGVPANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: OBG_POLAQ
Sequence: MKFIDEARIEVIAGQGGSGSASMRREKFIEFGGPDGGDGGKGGSVWATADRNINTLIDYRYAKTHTAKNGEPGRGADCYGRAGDDIELRMPVGTIISDYETGEPIADLTTHGERLCLAQGGVGGWGNIHFKSSTNRAPRQKTNGKEGERRKLKLELKVLADVGLLGMPNAGKSTLITAVSNARPKIADYPFTTLHPNLGVVRVGNERSFVIADIPGLIEGAAEGAGLGHRFLRHLQRTGVLLHLVDIAPFDENIDPVADAVAIVNELRKYDEALVEKPRWLVLNKVDMIPEEDRKKVVADFIKRFKWKGPVFEISALTGLGCDKLCYALQDYLDSVRRDRDDAEERAADPRYQDQAADKSPD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP450_HELAN
Sequence: LGELKHLHYLHAALHESMRLYPPVQFDSKFAKHDDVLPDGTFVKRGSRVTYHPYAMGRMERIWGADSLEFKPERWIRDGEFKQERAYKYPVYQGGVRVCLGKEMSLVEMASVALCLIRRFDVSVVNHSQLRFAPGLTATVSGGVHATVRRRDLSQ
What are the official names of this protein?
Cytochrome P450.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: TCPE_VIBCH
Sequence: MKIISKKYRLELYSMLVDLLNDNIPLYDALNKIQNEGVGIYDKNFIKSIELIKDRMKSNSSLTDALTGLIPDKEVLMINVAENSGKISSGIAAIRKNIIDADEIKSKAISSMITPSVMLIVTMVVIAGYSVKVFPTFESVLPVSRWPGVTQALYNLGFSLYEGLWIKVLIFVAIFITILVFMSKNITGNFRDGFLDKLPPFNFVKHIAATEFLANMSMLLDSRVPFKEGLDIVDHKTTRWLSSHLQRMKANMQEGLDYKQALDTNLLDKKMLLTMAVYSELPNFSDVMQKLAIEANINLHKKIATLAGVMKNISLITLALSVIWIFGAIFSLVDKLSSSL
What is the function of this protein?
Probably involved in cholera toxin receptor (GM1) interaction in order to bring the cells within close proximity of the ganglioside for efficient toxin delivery.
What are the official names of this protein?
Toxin coregulated pilus biosynthesis protein E, TCP pilus biosynthesis protein TcpE.
What is the protein family that this protein belongs to?
Belongs to the GSP F family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LJ1_HHV6U
Sequence: MSAERSTARRGVSTRVRSTPSLARAGPPRERPRPFSLLRRILVCPLRLCLPSLSLSPSLAGAIGSSRSPSPLNYAPSAPIPSSALSGGAGGGSRIHDTRVFRARRLGPQPMGSFFHASRSGARVGEKHGASHSGVRARVGGWVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVRVSRWFPLAPCQATVGPRRWHVARDVVLNCLHVSPRYAPSTYPPATTTWVGCACLCVCVCTRPW
What are the official names of this protein?
Uncharacterized protein LJ1.
Protein: DNAK_BACC3
Sequence: MSKIIGIDLGTTNSCVAVMEGGEPKVIPNPEGNRTTPSVVAFKNEERQVGEVAKRQAITNPNTIMSVKRHMGTDYKVEVEGKDYTPQEISAIILQNLKASAEAYLGETVTKAVITVPAYFNDAERQATKDAGRIAGLEVERIINEPTAAALAYGLEKQDEEQKILVYDLGGGTFDVSILELADGTFEVISTAGDNRLGGDDFDQVIIDHLVAEFKKENNIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFISAGAAGPLHLELTLTRAKFEELSAGLVERTLEPTRRALKDAGFAPSELDKVILVGGSTRIPAVQEAIKRETGKEPYKGVNPDEVVALGAAVQGGVLTGDVEGVLLLDVTPLSLGIETMGGVFTKLIERNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMSADNKTLGRFQLTDLPPAPRGIPQIEVTFDIDANGIVNVRAKDLGTSKEQAITIQSSSGLSDEEVERMVQEAEANADADQKRKEEVELRNEADQLVFQTDKVVKDLEGKVDAAEVAKATEAKEALQAAIEKNELEEIRAKKDALQEIVQQLTVKLYEQAQAAAGQAEGAEGAQDAGAKKDNVVDAEFEEVKEDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ADAD2_MACFA
Sequence: MASASQGADDGSRRKPRLAASLQISPEPRPWRPLPPQAQGAWEPAPAMDHAEGGQPQVSVLRDSGPGAGAGVGELGAAQAWENLGEQMGRTPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLGIILLFREDQQPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLESPESPQTSSRPPPPPLSVDSILTHGQRCAALVSAGFDLLLDERSPYWACKGTVAGVILEREIPGARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGAKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFSGPPVAPSEPTPDTCHGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQVARAVGKPYLLALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN
What is the function of this protein?
Required for male fertility and normal male germ cell differentiation.
What are the official names of this protein?
Adenosine deaminase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the ADAD family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Diffusely cytoplasmic early in pachytene spermatocytes and coalesces into several perinuclear granules by late pachynema.
Protein: ORFC2_GOCV
Sequence: MPRRGDHLSDLFGLVHRLEGMSTLWNNILHYLRQIPELETARLFLPGSLQAQQLSHSFADSGIPAGEVCLLSLLSLRRLSRTCSYPDCRTQLRHSNLQR
What are the official names of this protein?
Uncharacterized protein ORFC2.
Protein: SCED_STAEQ
Sequence: MKKTLVASSLAIGLGVVAGNAGHDAHASETTNVDKAELAQKALTNDQSLNESPVQEGAYNINFDYNGNSYHFESDGSTWSWSYESTNNATQPVQPSQSQVATQQQPVQVSAPQNEQTAQPQTKSTSTSQTSSSKASSGSSVNVNSHLQQIAQRESGGDIHAINPSSGAAGKYQFLQSTWDSVAPSQYKGVSPAKAPESVQDRAAVKLYNTGGPGHWVTA
What is the function of this protein?
Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells.
What are the official names of this protein?
Probable transglycosylase SceD.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. SceD subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PTH_YERPE
Sequence: MSSIKLIVGLANPGAEYAQTRHNAGAWYVDLLAERHNQSLKEESKFFGYTARLNLAGQDIRLLVPATFMNLSGKAVAAMASFYRILPEEILVAHDELDILPGMAKLKLGGGNGGHNGLKDIQNKLGNNPNFYRLRIGIGHPGDKSKVTGFVLGKPPASEQTLIDDAIDESIRCTEVLLNEGMTKAMNRLHAFKASA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_PROMH
Sequence: MFEINPVKHKIEEVAERTQVLRGYLDYDAKKERLEEVNAELEQPDVWNEPEKAQALGKERSSLEAIVETIDQLEQGLEDVSGLLDLAVEADDEETFNEAVAELEGLNKKLEQLEFRRMFSGEYDSADCYLDLQAGSGGTEAQDWASMLMRMYLRWAESRGFKTEIIEESDGDVAGLKSATIKIIGEYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDNIDIEINPADLRIDVYRASGAGGQHVNKTESAVRITHVPTGLVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNADKQVMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGDLDKFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_MACCJ
Sequence: MNKLAIEIVTPNGSIYSETEAELIVLQTESGEMGVMAGHIPTVAPLKIGAVRVTKPGNDKDYIAVTEGFAEIRPQQVSVLVQAAEQAEGIDIERAKESLKRAEARLNEDKAAHVDFHRAERALHRAINRIEVAKFR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AROE_BARBK
Sequence: MVDLVDHKKICSRVFVVGYPIHHSKSPKIHKFWLKYYGLQGESVSEEVTVREFSNFIASIKKGNFLGGNVTSPHKQEAFRLADYKDGIATAIGAANTLWIEGKKLLATNSDAYGFSANLDDFVPGWAGETALVFGAGGAARAIIYALKKRKFERIFLFNRTKKNADDLAEYFGKSTIKVYDWCSSCEKARQADLIVNTTSMDMINFSERENGAFFDFHKTKPTALVTDVVYTPLITPFLQQAKAHGLKTVNGLGMLLHQAVPGFEKWFGVRPSVTKELRAAILEDMGENRG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: KSG1_ARATH
Sequence: MASVGIAPNPGARDSTGVDKLPEEMNDMKIRDDKEMEATVVDGNGTETGHIIVTTIGGRNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNRELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRALSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRSAALDTLVHPFFDELRDPNARLPNGRFLPPLFNFKPHELKGVPLEMVAKLVPEHARKQCPWLGL
What is the function of this protein?
May mediate extracellular signals to regulate transcription in differentiating cells.
What are the official names of this protein?
Shaggy-related protein kinase alpha, ASK-alpha, Shaggy-related protein kinase 11, AtSK11.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Protein: GSTE_PSEP1
Sequence: MLKLHGFSVSNYYNMVKLALLEKGLPFEEVTFYGGQAPQALEVSPRGKVPVLETEHGFLSETSVILDYIEQTQSGKALLPADPFEQAKVRELLKEIELYIELPARTCYAESFFGMSVEPLIKEKARADLLAGFATLKRNGRFAPYVAGEQLTLADLMFCFSVDLANAVGKKVLSIDFLADFPQAKALLQLMGENPHMARIMADKEASMPAFMEMIRSGKR
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_RUEST
Sequence: MIHKNWAELIKPTQLEVKPGNDPARQATLVAEPLERGFGLTLGNALRRILMSSLQGAAITSVQIDNVLHEFSSVAGVREDVTDIILNLKQVSLRMEVEGPKRLSINAKGPAVVTAGDIAETAGIEVLNREHVICHLDDGADLFMELTVNTGKGYVSAEKNKPEDAPIGLIPIDAIYSPVKKVSYDVQPTREGQVLDYDKLTLKVDTDGSITPEDALAFAARILQDQLSIFVNFDEPESAGRQDEDDGLEFNPLLLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLSGMGLHLGMDVEDWPPDNIEELAKKFEDSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL2_MYCTU
Sequence: MAIRKYKPTTPGRRGASVSDFAEITRSTPEKSLVRPLHGRGGRNAHGRITTRHKGGGHKRAYRMIDFRRNDKDGVNAKVAHIEYDPNRTARIALLHYLDGEKRYIIAPNGLSQGDVVESGANADIKPGNNLPLRNIPAGTLIHAVELRPGGGAKLARSAGSSIQLLGKEASYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRMRWKGKRPSVRGVVMNPVDHPHGGGEGKTSGGRHPVSPWGKPEGRTRNANKSSNKFIVRRRRTGKKHSR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PSTB_PROMT
Sequence: MNKKNIKTTSSVSLDNVSIRYGNSVAVKNVFCDIEKNQVTSFIGPSGCGKSTVIRAINRMNDLIEGCKLSGSVIFEGIDIYAEDIDPVEVRRRIGMVFQQPNPFPKSIYENIAFGARVNGYKGNMDQLVEESLTKAAVWDECKDKLNESGYSLSGGQQQRLCIARTIAIEPDVILMDEPCSALDPLSTLKIEETIHELKKNFTIIIVTHNMQQANRVSDYTAFFNTEKKDKDLGGKIGFLVEFDKTKNMFNSPKQKSTQDYISGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.