PharMolix/UniProtQA huggingface dataset:
Protein: ADA2A_HUMAN
Sequence: MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.  The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine.  For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.
What are the official names of this protein?
Alpha-2A adrenergic receptor, Alpha-2 adrenergic receptor subtype C10, Alpha-2A adrenoreceptor, Alpha-2A adrenoceptor, Alpha-2AAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2A sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TOLB_ECO57
Sequence: MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQWAGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVGQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQNQDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: UXUA_ECO57
Sequence: MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFSMCTGSYGVRADYDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSH
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: RS15A_DICDI
Sequence: MVRISVLNDCLNSIVNAERQGKRQVLVRPSSKVIVKFLEVMMKKRYIGEFEIVDDHRSGKIVIDLIGRINKCGVISPRFDVTLDEIEKWASYLLPSRQFGHIVLTTSLGIMDHNEAKTRHTGGKLLGFFY
What are the official names of this protein?
40S ribosomal protein S15a, Ribosomal protein S24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: HYIN_BRAJP
Sequence: MVRGRHRSRDPQRRDLRGRDRRSASRTDARRQSAAERGCRRSQRGSAEGCACGRQTGPRAARSACCTACPSRSRRMSTTEGRPNFNGVPANKDFVAPSDSPVVHNLKKAGAIVIGLTNTPEFSFRGFTDNPLHGLTLNPWDPNITCGGSSGGAGSAVAAGIGTIAHGNDIGGSLRWPAHCNGVATIKPTQGRIPAFNGSATAERPMLAHLMSAQGPLARHVGDVRLALDVMSQADPRDPWWVPAPLAGPRPKGPIKVALARIPEDMDVDPSVRAALRQAADHLERSGYRVTEVDVPDIDGVWQTWCDIITNETVVMQEAGMLKVTSEDFHKAWGGMKTKANVLDLKAWMQATAARNGHIRAWQLFFEEYPVVLAPTTVKPTPGPRDDTVSADRVKEIFWGEIRFISAINVLGLPGAVVPVTLHDGKPIGVQLIAGRYREDLALDAAAAIEKRAGVLAHRLWETME
What is the function of this protein?
Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).
What are the official names of this protein?
Indoleacetamide hydrolase, IAH, Indole-3-acetamide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: NDK_PSEA8
Sequence: MALQRTLSIIKPDAVSKNVIGEILTRFEKAGLRVVAAKMVQLSEREAGGFYAEHKERPFFKDLVSFMTSGPVVVQVLEGEDAIAKNRELMGATDPKKADAGTIRADFAVSIDENAVHGSDSEASAAREIAYFFAATEVCERIR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_SHESW
Sequence: MTTVPKNAVAKTLYQKVWDAHVVATPEGEAPIIYVDRHLVHEVTSPQAFSGLKVAGRKLRAPEKTFATMDHNTSTRSASLDALSPMARTQVETLAQNCKDFGVRLYDIHHPNQGIVHVMGPELGITLPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLRQLKAKTMKIEVRGHVSDGVTAKDIVLAIIGKIGMDGGTGYVVEFCGEAIEALSMEGRMTVCNMAIEMGAKAGMVAPDQTTFDYLAGREFAPKGEDWAEAVAYWQAIKTDDGAVFDAVVELDAADIAPQLTWGTNPGQVVAIDGKVPNPLDEANPSTRASMEKALEYIGLSAGTPMTDISINKVFIGSCTNSRIEDLRSAAVHAKGRKVASGVTAIVVPGSGQVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNDDRLEAGDRCASTSNRNFEGRQGRGSRTHLVSPAMAAAAAVAGHFVDIRKPY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MBF1_KLULA
Sequence: MSEWEPSTVIGRKVRIGGGGPRQQVARTQGQINEARRSGMVLSVDKKYGTTNSKSSPEGQRLTKVDRETDIVKPKKIDVSVGKAIQKGRQDKNLTQKDLATKINEKPTIVNDYESGRGIPNQQILGKMERALGIKLRGKNIGEPLGGPKK
What is the function of this protein?
Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators.
What are the official names of this protein?
Multiprotein-bridging factor 1.
What is the protein family that this protein belongs to?
Belongs to the MBF1 family.
Protein: CRGA_STRCO
Sequence: MPKSRIRKKADYTPPPSKQATSIKLTSRGWVAPVMLAMFVIGLAWIVVFYVTDGSLPIDSLGNWNIVVGFGFIAAGFGVSTQWK
What is the function of this protein?
Involved in cell division.  Coordinates growth and cell division.  May act as an inhibitor of Z-ring formation.
What are the official names of this protein?
Cell division protein CrgA.
What is the protein family that this protein belongs to?
Belongs to the CrgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes at discrete foci distal from growing hyphal tips.
Protein: MTLD_ECOLC
Sequence: MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVDAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGLVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYSLPHKNLIQGIAGAMHFRSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: Y1598_STRT2
Sequence: MMNMQNMMKQAQKLQKQMEKSQAELAATTFTGKSAQDLVVAELTGDKKVVNITFADAVVDPDDVETLQDMTVQALNDALGQIDEATKKSMGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein stu1598.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AROB_NOCFA
Sequence: MTEPSRIQVRTADPYPVIIGRGLLGELVESVTGATSGVRTVAIFYQPPLAETAEVVRKALADTGIDAHRVEIPDAEAGKDLAVAGFCWEVLGRIGLTRNDVVVSLGGGAATDLAGFVAATWMRGVRIVHVPTTLLAMVDAAVGGKTGINTEAGKNLVGCFHEPTAVLVDLATLETVPRNEIVAGMAEIIKAGFIADPVILELVERDPQAALDPAGPVLPELIRRAIQVKADVVAADLKESSLREILNYGHTLGHAIERRERYRWRHGAAVAVGLVFAAELGRLAGRLDDATADRHRTILEAVGLPTTYDADALPQLLDAMQTDKKTRSGVLRFVVLDGLAKPGRLEGPDPSLLAAAYSAIAREESPSGGAILL
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_BURP0
Sequence: MFQGASALTLDAKGRMSVPSRYREALQGQAEGRVTVTKHPDGCLLLFPRPEWEVFRAKIAALPMDAHWWRRIFLGNAMDVDLDSAGRILVSPELRMAAGLEKEVMLLGMGSHFELWDAQTYTAKEQAAMAQGMPEALKNFTF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TPMT_SHESW
Sequence: MEPGFWHEKWYKQQIGFHQQDINPFLVQYWQRLALPAGAKVFVPLCGKSLDMCFLAEQGHQVIGCELNELAVQQFFSDNQLEMTQTVEGEHQHYQTEQVSLYQGDIFTLPKRITQDVTAFYDRAALIAWPEEMRAQYAKQLANLLPSGSLGLLVTLDYPQETLNGPPFAVSPNWIEAHLTDDFEIQALACQDVLADNPRFVKKEVPWLNEAAYLLKRK
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_STRP8
Sequence: MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREGVMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTILNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEFIDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSYDVAMNSYGSDKPDTRFEMLLQDLTVTVKGIDFKVFSEAPAVKAIVVKGNADRYSRKDIDKLTEFAKQFGAKGLAWVKVTDGQLAGPVAKFLTAIETELSSQLKLAENDLVLFVADTLEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPTPESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANDQFGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLVSENQLEELSLQIESHD
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_SYNJA
Sequence: MEADVQRAQQAQLEKGSSVPPWTGIPLQKGLGQRLRQHVNPLQAQYQQPTPPPHWERVYRRLGQPLHLDIGSGSGRFLLRMAQEQPDWNFLGVEIRQPLVERANAWRDELGLDNVHFLFANINVSLRHLFAPGDLSRVTIQFPDPWFKKRHHKRRIVQPRLVADLALLLQPGSPVFLQSDVREVAEEMVDRFLEHPQFWNPYQGPIDDNPFGIPTEREWQCLQLGLPIYRYWLERR
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RBSD_STAAS
Sequence: MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPA5A_PHLPR
Sequence: ADLGYGPATPAAPAAGYTPATPAAPAGADAAGKATTEEQKLIEKINAGFKAALAGAGVQPADKYRTFVATFGPASNKAFAEGLSGEPKGAAESSSKAALTSKLDAAYKLAYKTAEGATPEAKYDAYVATLSEALRIIAGTLEVHAVKPAAEEVKVIPAGELQVIEKVDAAFKVAATAANAAPANDKFTVFEAAFNDEIKASTGGAYESYKFIPALEAAVKQAYAATVATAPEVKYTVFETALKKAITAMSEAQKAAKPAAAATATATAAVGAATGAATAATGGYKV
What are the official names of this protein?
Pollen allergen Phl p 5a, Allergen Phl p Va.
What is the protein family that this protein belongs to?
Belongs to the Poa p IX/Phl p VI allergen family.
What are the subcellular locations of this protein?
Secreted.
Protein: LLDD_KLEP7
Sequence: MIISAASDYRAAAQRILPPFLFHYIDGGAYAEHTLRRNVEDLSDVALRQRILRNMSDLSLETTLFNEKLAMPTALAPVGLCGMYARRGEVQAAGAADDKGIPFTLSTVSVCPIEEVAPTIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAALRRYWQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDITILADSGIRNGLDVVRMIALGADSVLLGRAYLYALATHGKQGVANLLNLIEKEMKVAMTLTGAKSIREISRDSLVQNAEALQTFDALKQNNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PH4H_RALSO
Sequence: MAIATPTSAAPTPAPAGFTGTLTDKLREQFAEGLDGQTLRPDFTMEQPVHRYTAADHATWRTLYDRQEALLPGRACDEFLQGLSTLGMSREGVPSFDRLNETLMRATGWQIVAVPGLVPDEVFFEHLANRRFPASWWMRRPDQLDYLQEPDGFHDIFGHVPLLINPVFADYMQAYGQGGLKAARLGALDMLARLYWYTVEFGLIRTPAGLRIYGAGIVSSKSESVYALDSASPNRIGFDVHRIMRTRYRIDTFQKTYFVIDSFEQLFDATRPDFTPLYEALGTLPTFGAGDVVDGDAVLNAGTREGWADTADI
What are the official names of this protein?
Phenylalanine-4-hydroxylase, PAH, Phe-4-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Protein: PTH_STRP8
Sequence: MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNFKAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKLRLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVISHVMGQFNTEDNIAISLTLDRVVNAVKFYLQENDFEKTMQKFNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_CALS8
Sequence: MNKFFLIGIGGISMSAIALILKNHGHIVEGSDMQESITTRMLREKGINVYIGHDENHIKGDEIVIFTAAIPKDNPELVKAKRLGLKVYERAEFLGMLMKDYKNVIAVSGTHGKTTTTSMIGYILKKALLNPTVLVGAFVKQLGGNFCIGSSEYLVVEACEYVDSFLNFNPSIGVILNIDNDHLDYFKDIESIKDSFRKFALKIPQNGFIVANLDDENVYSVASYLKQNVIYFSTKTKADFWADNITSCNGYYEFDVVNKDFKHLCHIKLNIPGFHNVYNSLAAFSVAYTLGIDKNTIKEAIFEFCGASRRLEKLGKIDGIVLYDDYAHHPTEIEATLRTLKKLAKEKVIVIFQPHTFSRLKSLMEGFVKSLSLADKVIVTDVYAAREKNVYGVSSKDLYEKLKKAGVDCEYIDQFEKIAEYVLNTAQKGDIVATIGAGDVNKCIELILDKSPVKS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFO6_HALMA
Sequence: MNVDALTGGFDRRDWQEQTATDNPVRFAMIGVGWWTTEQAMPAVDAGDLCETTVLVSSDREKAADVAADSETVEHAITYEEFHDGAASDAYDAVYIVTPNALHLPYVETAAELDKAILCEKPMEATIERAERMVEVCDEHDATLMIAYRMHTEPAVRRAKDLIDEGYIGEPLFVHGNMTEPILELVPDPDQWRLDGELSGGCAVMDIGIYPLNTSRFLLDADPVAVRGTVASVQEEFADVPDEHGAFQLDFPGHVYAVCTASQNAHLDSHISVLGTEGKVRVEPAFYPWDDRALQLSHEGTTVEIDFEQIDQMEEEFEYFAHCLLTDTEPYADGEHGLVDINTIKSVYEASETESTVRLD
What is the function of this protein?
NADP-dependent D-xylose dehydrogenase involved in the degradation of D-xylose, a major component of hemicelluloses such as xylan.  In addition to D-xylose, oxidizes D-ribose at similar kinetic constants, whereas D-glucose is oxidized with about 70-fold lower catalytic efficiency.
What are the official names of this protein?
D-xylose 1-dehydrogenase [NADP(+)], XDH.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: RL17A_SCHPO
Sequence: MVRYSASPALETKCAKARGAYLRTHFKNSREVAFTINGMSLKKAFIFLDNVKEHKQAVPFRRFNGGVGRTAQGKEFGVTQARWPVKSVKFFYDLLKNAEANAEAKGLDMDKLIIKHVQVNAAPKQRRRTYRAHGRVTAYLSSPSHIEIIVAEEEEAVPKANDTVSRVSLKQGAKARNLAARKAITAA
What are the official names of this protein?
60S ribosomal protein L17-A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: TSAC_PSEPF
Sequence: MVNSWRVQQAAREIRAGAVIAYPTEAVWGLGCDPWNEEAVDRLLAIKNRSVDKGLILVADNIRQFDFLFEDFPQDWIDRMASTWPGPNTWLVPHQNLLPEWVTGVHDTVALRVSDHPQVRDLCSLVGPLISTSANPQGRPAARTRLRVEQYFRGQVDLVLGGALGGRKNPSLIRDLATGNIVRPA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_ECO27
Sequence: MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED17_ASHGO
Sequence: MEPDDGHNSLNQDNGIPIVLDPNLINLRSRAASATVTTNGTTADSSEDSGSQQSVSSAPIQQNSEEHSLVSNPYETYGRMPLQKLIPLILQMRNASSFSELTEEDLLRDIEREEKGILTTGLDVEGDIEMGDADEESDLKPQEITDDDSNARLKPNNDSAIPQEEFNQMKREVLEHINLALNESSLSLEFISLLLSSVRPSVGVGSMSPFLKRSVPTASLNADKVELPPKNKTETLTLAVINRGWKLRSLEDSKALLKENYAKLQKSLEVEHAHWAMISQHISSTDVVFKMRDRQTGKRSLAVKYGYEDSGSLYKQDRGVAVLRHNMDLNKLELVPISNSKEEVHITANSVERFMRVHIYTKIEEEDDYILSGESSIDDQSLLQPCHDDISRQIARLKFFIFERELMYQLKKEAVSLMPYGVNFENENKVVLESPGERIEFEMVPLDDSALLSTHEPRRVNDKRANIILILLRMLLVVIHKKQLRRGLKPATSKHKYRADGDLLLLRPVLGRIRHRNYLQVVKRVVTECVLNIVPGSSIELLPQRSEPDTLHAREANIASLNKQIGLFDKILRMPRSELRTSLGAKGVIDLTLKSSNYCNAIIQVIYADSAGKTVFDTVFTELKELEEFLHFIVSEYVL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 17, Mediator complex subunit 17.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 17 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS15_ALIF1
Sequence: MSLNAETKAAIVAEYAQSEGDTGSPEVQVALLTASINHLQGHFANHKHDHHSRRGLLRMVSSRRKLLDYLKGKNLARYQDLIKRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RR15_WHEAT
Sequence: MKKKGGRKIFGFMVKEEKEENRGSVEFQVFSFTNKIRRLASHLELHKKDFSSERGLRRLLGKRRRLLAYLAKKNRVRYKKLIGQLNIREQ
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NU4LM_LEPMS
Sequence: MPSISINITLAFTMALTGMLVFRSHLMSSLLCLEGMMLSMFILSILFIMNMHFTVSFIMPILLLVLAACEAAIGLALLVMVSNTYGLDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GPDA_LEPBL
Sequence: MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQIESINRNHINNKHLPDFTLPEKLTASKDLRTVVQGKDMIVSSPPSHALTEILREIKEYLPEKVPIVSASKGIENGTLRLVSEIFESELPGKYHSYLSYLSGPSFAKEIIQKVPTIVSIASRSETTARKVQEIFSFLYFRTYWTPDVIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPSGMGDLILTCCGGQSRNRTVGFRLGKGETLEQILSGMNEVAEGIKTTQSAYELSQKLGIEMAITNEVYKMLYEDKNPKEVVKDLMKRDLKREGVLV
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_GEOKA
Sequence: MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSAVIRKERRGDYLGGTVQVIPHITNEIKERVFRAGRETNADVVITEIGGTVGDIESLPFLEAIRQIKSDVGRENVMYIHCTLVPYIKAAGEMKTKPTQHSVKELRSLGIQPNVIVVRTEMPMPQEMKEKIALFCDIDPKAVIEARDADTLYAVPLMLQEQKLDQIVCEHLRLNCREADMTEWKALVEKVRNLSKTTKIALVGKYVELPDAYISVVEALRHAGYAFDTDIDIQWINAEHVTRDNVADLLKDADGILVPGGFGDRGVEGKIEAIRYAREQRVPFLGICLGMQLASIEFARHVVGLSGAHSSEFDPNTPHPIIDLLPEQKDVEDLGGTLRLGLYPCKLQEGTLAYAAYGDEVIYERHRHRYEFNNQYRPIMEEHGFVFSGTSPDGRLVEVIELKDHPWFVAAQFHPEFTSRPTRPQPLFREFVRASLKE
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.