PharMolix/UniProtQA huggingface dataset:
Protein: PFD1_MOUSE
Sequence: MAASVDLELKKAFTELQAKVIDTQQKVKLADIQIEQLNRTKKHAHLTDTEIMTLVDETNMYEGVGRMFILQSKEVIHNQLLEKQKIAKEKIKELEQKKSYLERSVKEAEDNIREMLMARRAQ
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
What are the official names of this protein?
Prefoldin subunit 1.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: PEX5_SCHPO
Sequence: MSVEAGCSTLSNPLKKLTSTAVVNNSTPSAQYRKHLTKSQSRTYAPLQTLSEDQFTSFKNLQGNNSPLGNVVKNPVSLKTGNHTGTTTRGGSKENWVHSFSSLQQQNSKSAWTSEFSEVFLNSSENDRFRNLNQPLKQSFFGSAGLNLSSNTEIPLQSSLAIDETELAKKFEEASQISNKLEKEKDATGSKSIEELWEEHQKQLKNAGLEPASLEEYQKQWEDFLKSNNISDDPYTSSVNSFANDNLAHNKNIDPQIFQHSDTDNVVENSLQTEDVYSQNQDESSEVVKELNGIDPFVEAMNLIKNGGSISKAAVLLEQSVKENPQHFEAWKWLGRIHTLLGNESRVVEALLEAVKLDSTNLDLMMDLAVSYVNQSLNVQALVCLEDWIVNSFPQYRNRFAKINERFEEKDSANDLLKMQMYFLDVAYELSLAKKRSSKVQAGLGIIMYMLKEYERSADCFRQALQDEPSNEILWNKLGAALTNAEKNTEAVSSYNRAVSLQPQYVRVRSNMAVSNINLGYFEDAAKHLLAAIDIIQNSSTSMESCESNEELWEMLRKVFLIGFQSTDLASQSYPGANTSYIRAQLSDLQGWPGVELE
What is the function of this protein?
Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type).  Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins.  PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle.
What are the official names of this protein?
Peroxisomal targeting signal receptor, PTS1 receptor, PTS1R, Peroxin-5.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal targeting signal receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane (By similarity).
Protein: GARS_MOUSE
Sequence: MPCLLPSLLRATRAALPLLSPPRVVAASASQRLLSAPAQPAASRSSMDSAEELLAPLRLAVRQQGDFVRKLKEDKAPQVDVDRAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQAWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSAEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPTTGNDLSPPVPFNLMFQTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPTEKDHPKFQSVADLCLYLYSAKAQVTGQSARKMRLGDAVEQGVINNSVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPNKGAVGKAYKKDAKLVLEYLSACDECYISEMELLLSEKGEFTIETEGKTFQLTKDMVSVKRFQKTLHVEEVVPSVIEPSFGLGRIMYTILEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRNGVSHKVDDSSGSIGRRYARTDEIGVAFGITIDFDTVNKTPHTATLRDRDSMRQIRAEVSELPNVVRDLANGNITWADVEARYPLFEGQETGKKETVEE
What is the function of this protein?
Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP).  Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.  Thereby, may play a special role in Ap4A homeostasis.
What are the official names of this protein?
Glycine--tRNA ligase, Diadenosine tetraphosphate synthetase, Ap4A synthetase, Glycyl-tRNA synthetase 1, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Cell projection, axon. Secreted. Secreted, extracellular exosome. Note=Associated with granules in cultured neuron cells (By similarity). Secreted by motor neuron and differentiated myotube cell lines, but not by undifferentiated myoblasts, possibly through the exosome pathway (PubMed:26503042).
Protein: PSBL_ANGEV
Sequence: MTQPNPNKQTVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL10_MYCA9
Sequence: MAKTDKVTAVAEITEQFKDSTATVITEYRGLSVSALATLRRSLGASATYAVAKNTLVKRAAADAGVEGLDELFAGPTAIAFIKGEPVDAAKAIKTFAKDNKALIIKGGYMDGRALSVAEVERIADLESREVLLAKLAGAMKGNLNKAAGLFAAPASQVARLAAALQEKKAGEESAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RLMH_ECO7I
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLA_SALPB
Sequence: MKLEVLPLDQKTFSAYGDVIETQERDFFHINNGLVERYHDLAKVEVLEQDRTLISINRAQPAAMPIVVHELERHPLGTQAFVPMNGEAFVVIVALGDDKPDLSTLRAFISNGRQGVNYHRNVWHHPLFAWQTVTDFLTVDRGGSDNCDVESIPTHELCFA
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the utilization of allantoin as nitrogen source.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: SYW_HYPBU
Sequence: MEGYRLDPWASAIRLEYEKLFRYFGIKPFQPLLPEVEKAFGKPHRLMRRGIIFGHRDYEKILEAYRSGERIALVTGFMPSGKFHFGHKMVADQIIYYQKLGFEIFVVIADAEAYAVRRLDRRKIIEIGLYEYVANLIALGLEKNKHTHIYFQTNYETPYYRLIQMFSRRVTLEEMSAIYGDLEPSKIMAALTQAADILHPQLDYFGGFKYVVVPVGADQDPHIRLTRDIAARFENELGLRRPASTYHRFQTGLDGNKMSSSRPEYTIFLTDPVDIAVRKLKRALTGGRATVEEQRRLGGEPEKCTVYEFYLYHLIEDDTQLRKIYEDCRGSRLLCGPDKEYAAELLAKFLEEHQRRLERARDRVLEYVEPPKF
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_LIMRD
Sequence: MADNSHTRVVVGMSGGVDSSVTALLLKRQGYDVVGVFMKNWDDTDENGVCTATEDYKDVAKVASKIGIPYYSVNFEKEYWDRVFKYFIAEYKKGRTPNPDVICNKEIKFKAFIEYANQLGADYVATGHYADVKRDENGRMHLMRAKDQHKDQTYFLSQLDYKQLDKVMFPLAGYTKPEIRKIAEEAGLATADKKDSVGICFIGEDGHFREFLSQYIPAQPGNMETLDGKVVGQHMGLMYYTIGQRRGLGLGGNKESNEPWFVIGKDMKKNVLYVGQGYENSHLYATHLEASDIHWVDDVVSRYGRDFHCTAKFRYRQTDVGVTVHLSDDDQMVTVEFDDPARAITPGQAVVFYDGEECLGSAIIDRAYSHDRQLQYV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_FRATW
Sequence: MKRTFQPSNLKRKRTHGFRARMKTLSGRKVIRNRRAKGRAKLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LGT_ECO55
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MOAC_VIBCM
Sequence: MMSQLTHINASGEANMVDVSNKADTVREARAEAYVRMAPETLQLILSGQHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEVQLEALPEQSSVRIESLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIENVRLLEKSGGKSGHFKVDA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: Y1178_THEPX
Sequence: MRFVIITGLSGAGKTQALKAMEDMGFFCIDNFPPALLPKLADLFYHSKNVDKVALGMDLRGGQFFEDIYSSLEFLKKNNYDYEIVFLEASDEVLIKRFKETRRKHPLSEEGRIVDGINEERKRLAEIRKIANSIIDTSNLTSSQLKEELSNIFLKGKKFKGIIIDIMSFGYKYGIPLDADLVFDVRFLPNPFYIEELRPLTGNDDKVKEYVMKWEEAKEFLKKLGDMIKFLIPYYIREGKSQLVIAIGCTGGKHRSVTIANALYEFLKKEDYSVILHHRDIGEE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Teth514_1178.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: Y4089_BACC2
Sequence: MQNKIQVKSVEKRENALIFCAENNEIEVKELSARNHVLVDSDNLSFLYILENESSFIYVSIPHTCWEAMHEAMNNDIVMFVRVNDVEMELENLKEEVEYLVENIEGNANYGEELVTAVEKVFL
What are the official names of this protein?
UPF0738 protein BCG9842_B4089.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.
Protein: COAA_MYCVP
Sequence: MARLSEPSPYVEFDRTQWRALRMSTPLKLTEDELVRLRGLGEKIDLLEVEEVYLPLARLIHLQVAARQALFATTAQFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWEHHPRVDLVTTDGFLYSNSELSRRNLMHRKGFPESYDRRGLMRFVTAIKSGADAACAPVYSHLLYDIVAGEKQIIEHPDILILEGLNVLQTGPALMVSDLFDFSVYVDARIEDIENWYISRFLSMRAGAFADPASHFHHYSTLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDSDHSINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTMCB_STACA
Sequence: MDTMSNSQQNKGIGRKVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWFPNKDLAQLAGPMITYLIPLLIAFSGGRLIHDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDEFVQPRTPQGFEMLFNNFSAGILGFIMTIFGFEVLAPIMKFIMHILSVGVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAHAGQSILYTIESNPGPGIGVLIAYMIFGKGTAKATSYGAGIIQFFGGIHEIYFPYVLMRPLLFVSVILGGMTGVATYSLLDFGFKTPASPGSIIVYAINAPKGEFLHMLTGVVLAALVSFVVSALILKFTKDPKQDLAEATAQMEATKGKKSSVASKLSAKDDNKAADNKTAETTTATAASNKAEDKDSDELLDDYNTEDVDAHNYNNVDHVIFACDAGMGSSAMGASMLRNKFKNAGLENIQVTNTAINQLPKNAQLVITQKKLTDRAIKQSPDAIHISVENFLNSPRYEELINNLKEDQD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
PTS system mannitol-specific EIICB component, EIICB-Mtl, EII-Mtl.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PANC_NITHX
Sequence: MPRAPAIARTLPSLRRALEGLRARRATVALVPTMGALHDGHLALVRQAKRRASKVVVSIFVNPTQFAPHEDFGSYPRTWKADMAKLAEARVDLVWNPDVGTMYPPDFATRILTEGPAMAGLEDRFRPHFFGGVATVVGKLFAQCRPDVALFGQKDYQQFKVVTRMATDLDLGVKIIGVPIVRERDGLAMSSRNAYLSAEQRAVAPTLHRVMKDAAKRLRNGDDLETVMADGAGTIVDAGFALDYFEARHAETLAPVRSIKDGPVRLLVAAKIGTTRLIDNIGV
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_BARBK
Sequence: MVSSKEIIQHRAKRVRRQIKAAANGRPRLSVYRSNQNIYAQIIDDVRGCTLASACTLEEGMKKSLRSGSDKKAAFAVGKLIAERAKKSGINEVVFDRGAYVYHGRVKALAEAAREGGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RNH_RHORT
Sequence: MSAAAGDEIKRVRVDMFTDGACSGNPGPGGWGTILRWGDTEKELWGGETPTTNNRMELMAVIRGLEALRRPVTVTIHTDSRYVHDGITGWIHGWKRNGWKTAAKKPVKNEDLWRRLDAALGTHDISWQWVRGHSGHVENERADELARRGTSEARQGKVDGQSSTIL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGI1_XENLA
Sequence: MAKERHSVGVIGAPFSKGQPRRGVEEGPKYLREAGLIEKLREFGNDVRDCGDLDFPDVPNDTPFNNVKNPRTVGKATEILANAVTAVKKADKTCQSIGGDHSLAVGTIAGHAAVHPNLCVVWVDAHADINTPSTSPCGNLHGQPLSFLMKELKAKMPAVPGFEWVKPCLRSKDIVYIGLRDVDPGEHYILKTLGIKYLSMIEVDYLKDDKVMEETLEYLVGKHKRPIHLSFDIDGLDPSIAPATGTPCPGGRTYREGRILHEQLHKTGLLSGVDTIWMESTSRGETKRDVEVTVKTALDMTLSCFGKAREGFHAST
What are the official names of this protein?
Arginase-1, Arginase, hepatic, Type I arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: PTRA_ECO57
Sequence: MPRSTWFKALLLLVALWAPLSQAETGWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMTPQNARIWYISPKEPHNKTAYFVDAPYQVDKISEQTFADWQQKAANIALSLPELNPYIPDDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFSSEPKADVSLILRNPKAMDSARNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGYFSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSITLKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQAVITQMLQAPQTLGEEALKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVVEPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE
What is the function of this protein?
Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.
What are the official names of this protein?
Protease 3, Pitrilysin, Protease III, Protease pi.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: 3SX9_DENPO
Sequence: TICHIQISKTHGILKTCEENSCYKMSVRGWIIGRGCGCPSAVRPRQVQCCTSDKCNY
What is the function of this protein?
When tested on muscarinic GPCR, specifically antagonizes the type 2 receptor (CHRM2) subtype (Ki/Kd=120-399 nM).  Ex vivo, it reverses the M2R-agonist-induced relaxation in rat and human arteries.
What are the official names of this protein?
Dendroaspis polylepis MT9, Three-finger toxin, 3FTx.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
Protein: HEM3_PSEAB
Sequence: MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKGLFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLPAGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFESRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHSDTALRVTAERALNKRLNGGCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAEAILEAVYGEAGHP
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PP396_ARATH
Sequence: MALLISCGEVTSSQFTVFRLLNQSLDFVSDNVSRLLAPIFTNLRDFEMRLSCIERPPSISGNHSHLCTEKWFSDQKDYDQKEDPEAIFNVLDYILKSSLDRLASLRESVCQTKSFDYDDCLSIHSSIMRDLCLQGKLDAALWLRKKMIYSGVIPGLITHNHLLNGLCKAGYIEKADGLVREMREMGPSPNCVSYNTLIKGLCSVNNVDKALYLFNTMNKYGIRPNRVTCNIIVHALCQKGVIGNNNKKLLEEILDSSQANAPLDIVICTILMDSCFKNGNVVQALEVWKEMSQKNVPADSVVYNVIIRGLCSSGNMVAAYGFMCDMVKRGVNPDVFTYNTLISALCKEGKFDEACDLHGTMQNGGVAPDQISYKVIIQGLCIHGDVNRANEFLLSMLKSSLLPEVLLWNVVIDGYGRYGDTSSALSVLNLMLSYGVKPNVYTNNALIHGYVKGGRLIDAWWVKNEMRSTKIHPDTTTYNLLLGAACTLGHLRLAFQLYDEMLRRGCQPDIITYTELVRGLCWKGRLKKAESLLSRIQATGITIDHVPFLILAKKYTRLQRPGEAYLVYKKWLATRNRGVSCPSILNHMHTEEQ
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g24830.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: PYRD1_DICDI
Sequence: MTINQLIVIGGGIAGLTCAESYSHLKPNDKVTILSCSPILKTVCNVQKISKVLESFEVFETQFTDIEFKNPNISVIICDVDSIDINNRIVKTDKGNFKYDYLSICSGAKPNLVKESPYLIGIRDTETIVDLKNRLSNAKRIVIVGNGGIALELIHEIKNCQIIWSIKDKHIGNAFFDKDAADFLFRSKQIIDDDNHDKKNVVKEQQQQQQKDGILLNEDELIAKNQNISSQSNSSLYKSESGSALGPQWYSKYNFKTTDQYNKNNQEKKYNFNENVNIQYSTFLDEIYSNHDKKLNQEIINNNNNGDGDDKEDWPIYVKLSNGNLFGCNFIISATGVIPNSTILTKDNNNNNNNKIIKLSNEGAIIVDEQMKTSVDRIYSAGDVCSIEWSESEVWFQMRLWSQARTQGRYTAQCIANESVKNTPQQDNLDQICTNFEFELFAHATKFFGFKVIMLGLYNAQGLNLNLDNNNQNEENQDNIKIYTREIIGEQYVKVILKNGRLIGSLLIGDTDLEETFENLILNQIDLSGYGAEILNPEIDIEDYFD
What are the official names of this protein?
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
Protein: SP5G_ANADE
Sequence: MEITEVRVFPVNEEKLKAYVTITLDHCFVIRDLKVIHGNTGLFIAMPAKRRKDGTFKDIAHPLNSDTREKMERTILAEYDRELKKGAAAPARATGTDPHED
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: ZAPB_YERE8
Sequence: MSFEVFEKLEVKVQQAIDTITLLQMEIEELKEKNNTLSQEVQEAAGGREALVRENEQLKQEQHVWQDRLRALLGKMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: DAP_BRUA2
Sequence: MPNIDLPTLEAFVHAIPQNYKGPGGAVAVVRNGEIVLRHAWGFADLAARKAMTPETRMPICSVSKQFTCAVLLDCIGEPEMLDSALAAYLDQFEDGRPAVRDLCNNQSGLRDYWALTVLCGAAPEGIFLPDQAQNLLRRLKTTHFAPGTHYSYCNGNFRILADLIEQHTGRSLADLLAERIFAPAAMKTAELIPDTALFNECTGYEGDTVRGFLPAINRIHWLGDAGICASLDDMIAWEQFIDRTRHDENGLYRRLSSPQTFADGAPAPYGFGLKFEETGGKRLTGHGGALRGWRCQRWHCADERISTIVMFNFEGNASDAALKMMNAALGIPPAKPVRAQANPGWFGSWLNPETGLVLSLEDAGGGRMKARFGTGPEIMDISGENEAQSSMTTLRRDGDMIHLARKDENLHLAMHRLKGEARQDIAGRYRSDELEADLLLVSEGGAIYGAFEGFLGKSDMYPLYAAGPDVWLLPVQRSMDAPSPGEWKLVFHRDAAGRITGVTVGCWLARGVEYKRL
What is the function of this protein?
Hydrolyzes N-terminal residues in D-amino acid-containing peptides.
What are the official names of this protein?
D-aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S12 family.
Protein: CAPSD_HASV7
Sequence: MASKSDKQVTVEVNNNNGRSRSRSRGRSQSRGRGRSFKITVNSKNRGRRQNGRNKLQSNQRVRNIVNKQLRKQGVTGPKPAICQRATATLGTIGSNTSGSTEIEACILLNPVLVKDATGSTQFGPVQALGAQYSMWKLKYLNVKLTSMVGSSAVNGTAVRISLNPTSTPSSTSWSGLGARKHLDVTVGKNAVFRLKPADLGGPRDGWWLTNTNDNASDTLGPSIEIHTLGKTMSSYLNQQFTGGLFLVELASEWCFTGYAANPNLVNLMKSTDKQVNVSFEGDNGTPLIMKVPDTSHFARTAVARSSLPTTLARAGQNTTSDTVWQVLNTAVSAAEIVTPPPFNWLIKGGWWFVKLIAGRSRAGMRSFYVYPSYQDALSNKPALCTGSVPGGMRVRAAIPTTLQFTQMNQPSLGHGEVTATLGRSIPTPGDTFKVVLTIGQPLAPNTLNNQTWVNKTTTAPQGQHVVKIAKDTSNYTTMQGFTPISNVTWYTEDFQPSEEPPPISGLQVLVDSRKKADVYAVQQYLNHPSNTKDQLTSIFLVKVTTSFQVNNHLSYFYRAAGTGTAVENFKIRGATSEQNISFSEGWYLMTNTATFNPPAPPGWIWKNVELDNNTPYIVDQGMMHLIMSPPVGTQLLFEMKTTVSGTRNVSHFDHDENPSPVWCDALDAADVWELPTETDTESEEDEDEDDEADRFDLHSSYGSEPEDDDENNRVTLLSTLINQGMTVERATMITKRAFPTCADKQKRSVHMDLLASGLSPGNVWSHACEEARTMGTNHMPNVSGDRGHAE
What is the function of this protein?
The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the VP70 virions.  This immature virion is composed of 180 VP70 subunits with 90 dimeric spikes and displays a T=3 icosahedral symmetry.  The mature virion is obtained by further cleavages resulting in three structural proteins VP25, VP27 and VP34.  This forms contains only 30 spikes located on the icosahedral 2-fold axes.  Plays a role in the attachment to target host cell.  This attachment induces virion internalization through clathrin-dependent endocytosis (By similarity).
What are the official names of this protein?
Capsid polyprotein VP90.
What is the protein family that this protein belongs to?
Belongs to the astroviridae capsid polyprotein family.
What are the subcellular locations of this protein?
Virion.
Protein: METC_BACSU
Sequence: MSKHNWTLETQLVHNPFKTDGGTGAVSVPIQHASTFHQSSFEEFGAYDYSRSGTPTRTALEETIAALEGGTRGFAFSSGMAAISTAFLLLSQGDHVLVTEDVYGGTFRMVTEVLTRFGIEHTFVDMTDRNEVARSIKPNTKVIYMETPSNPTLGITDIKAVVQLAKENGCLTFLDNTFMTPALQRPLDLGVDIVLHSATKFLSGHSDVLSGLAAVKDEELGKQLYKLQNAFGAVLGVQDCWLVLRGLKTLQVRLEKASQTAQRLAEFFQKHPAVKRVYYPGLADHPGAETHKSQSTGAGAVLSFELESKEAVKKLVENVSLPVFAVSLGAVESILSYPATMSHAAMPKEEREKRGITDGLLRLSVGVEHADDLEHDFEQALKEIAPVSVR
What is the function of this protein?
Catalyzes the transformation of cystathionine into homocysteine.  Also exhibits cysteine desulfhydrase activity in vitro, producing sulfide from cysteine.
What are the official names of this protein?
Cystathionine beta-lyase MetC, CBL, Beta-cystathionase MetC, Cysteine lyase MetC, Cysteine-S-conjugate beta-lyase MetC.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.