PharMolix/UniProtQA huggingface dataset:
Protein: MNME_PHOPR
Sequence: MNEYTDTIVAQATPPGRGGVGIIRVSGPKAKEVALAVAGRELKTRYAEYLPFKNEDGSALDQGIALFFKGPNSFTGEDVLELQGHGGPVLMDMMIRRILKLEGIRPARPGEFSERAFMNDKLDLAQAEAIADLIDASSEEAAKSAFRSLQGAFSTKVNELVEAVIHLRIYVEAAIDFPEEEIDFLSDGKVSNDLHGIIDNLEAVRREANQGSIIREGMKVVIAGRPNAGKSSLLNALSGKDSAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREASNEVERIGIERAWEEIQQADRVLFMVDGTTTNDTDPKDIWPDFIERLPESMGLTVIRNKVELTGEAAGICHVNNPPLIRLSARTGEGIDSLREHLKDCMGFSGTTEGGFMARRRHLEALEQAAQHLEIGKEQLEGFMAGEILAEELRLAQQHLSEITGEFTSDDLLGRIFTSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_SALHS
Sequence: MTDVTLKALAAERQVSVDRLVQQFADAGIRKSADDSVSAQEKQTLLAHLNREAVSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEEQAKREAQQKAEREAAEQAKREAAEKAKREAAEKDKVSNQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTATPEPVEDTSDYHVTTSQHARQAEDENDREVEGGRGRGRNAKAARPAKKGKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIESESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGTIKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRVGDMIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2648_SYMTH
Sequence: MPGDQVILLSLMALGVVARNALIVTAAGVVLILRVLALERFFPLLERRGLEAGLIFLLIAVLVPFATGEVGWAEIRQSFTSWTGLAAILGGIIAAVLSGYGVTLLQVKPEVIVGMVVGTILGVVLFKGIPVGPLAAAGFTAILLALVRGH
What are the official names of this protein?
UPF0756 membrane protein STH2648.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1161_CLOBA
Sequence: MGIKLINIGFGNIVSANRLVAIVSPESAPIKRIIQEARDRGMLIDATYGRRTRAVIITDSDHVILSAVQPETVAHRLSTKEEVVDEVDE
What are the official names of this protein?
Putative regulatory protein CLH_1161.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: RS20_EHRCJ
Sequence: MANHPSAKKMIKVIKKRTMVNRMRKSRAHNYVKKFLLALAAGNKELMVETFKKAESNLHKCVNKKIIHRNTAARKISRMALKLKTFDLQQQAKAL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: LY65C_CANLF
Sequence: MGAEYGCLPSTSQALYVILLIVLVRMSLVFVQFPKYLRCYRCLLETKELGCLLGSDICLAPPGSSCMTLLIKNSSSGSDIMVSDCRHKEQMSDCSYTRSSPVFGFWIFSRCCLREFCNNPQNRVFYIP
What is the function of this protein?
May have a role in hematopoietic cell differentiation.
What are the official names of this protein?
Lymphocyte antigen 6 complex locus protein G5c, Canine epididymal gene product 8, CE8, Epididymal secretory protein 8.
What are the subcellular locations of this protein?
Secreted.
Protein: CMCH_AMYLA
Sequence: MLIVAFKPGHDGAVAAIGDRRLLYSLESEKDSRPRYSPILATTVLDLAERLGEVPDVVALGGWSDLRPNRISYTGAGYSGIEEPTVTTSRFFGKEVKFFSSTHERSHIYMALGMAPRDDSPVQTVLVWEGDVGAFYVIDGHQRITRKVQVMSGPGARYSFLFGLADPTFPTTGGKPRLNDAGKLMALAAFGDSADADADITHVVERILKQDSMYPAPKGEYRDSVLYNAGVESPECKIAAALLTERLFETFAEVARQEMPEGSPLYISGGCGLNCDWNSLWAQLGHFSSVFVAPCTNDSGSALGTAIDALTTFTGDPHVDWSVYSGLEFVTDTQPDPARWTSRPLEHDELSGALAGGRVVAWVQGRWEIGPRALCNRSLLAEPFGAVTRDRLNEIKQREDYRPIAPVCRVEDLGKVFHEDFEDPYMLYFRRVRESSGLRAVTHVDGSARVQTVRDSGNPQMHRLLSAFAAQRGVGVLCNTSLNFNGEGFINRMSDLVLYCESRGISDMVVGDTWYQRAEG
What is the function of this protein?
Catalyzes the carbamoylation reaction in the cephamycin biosynthesis.
What are the official names of this protein?
3'-hydroxymethylcephem-O-carbamoyltransferase, 3'-hydroxymethylcephem-O-CASE, CCT.
What is the protein family that this protein belongs to?
Belongs to the NodU/CmcH family.
Protein: Y3206_SACS2
Sequence: MKEIIFTEKAPKPIGPYSQGVKVGDILYVSGQIPVDPKTNEVVGKNIEEQTIRVIENIKAVLEAAGYMLDDVVMSFVYLKDIKDFQRFNEVYSKYFSNKPPARVTVEVSRLPRDVLIEITVIAQKS
What are the official names of this protein?
RutC family protein SSO3206.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: YHEU_ECOL5
Sequence: MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKRQLQCGEAVLVWSELHETVNIMPRSQFRE
What are the official names of this protein?
UPF0270 protein YheU.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: AMPL2_ORYSJ
Sequence: MATAASTSAAAVAAASRLLVRRAPPRLLRRLPRAALAASRPSPPSSSSYGAAAVALGRQPLGHRARMGHTAAAAAAAGPALGLTKPNAVEPPQVSFAAKDVEFSEWKGDILAIAVTENDLVKGSDSKFENAVLKKLDGQLGGLLSEASAEEDFTGKAGQSVVLRLPGQGFKRVGLIGLGQNAPSTTTACKGIGESVASVAKSAQASSAAIVFASVGGIQEDFKLTAAAAIASGTVLGLHEDSRYKSESKKVHLKQVDLIGFGSGPEVDQKLKYANDLSSGVIFGKELVNSPANVLTPAVLAEEASNIASTYSDVFTATILDVEKCKELKMGSYLGVAAASANPPHFIHLCYKPPGGNAKRKLAIVGKGLTFDSGGYNIKTGPGCSIELMKFDMGGSAAVFGAAKALGQIKPPGVEVHFIVAACENMISGTGMRPGDIVTASNGKTIEVNNTDAEGRLTLADALVYACNQGVDKIIDLATLTGACVVALGPSIAGIFTPSDELAKEVAAASEISGEKFWRMPLEESYWESMKSGVADMVNTGGRQGGSITAALFLKQFVDEKVQWMHIDMAGPVWNDKKRAATGFGVSTLVEWVLKNSS
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Leucine aminopeptidase 2, chloroplastic, Leucyl aminopeptidase 2, LAP 2, Proline aminopeptidase 2, Prolyl aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ENGB_SHEPC
Sequence: MTESHIDFRRAKFLISAPDIAHLDQYLPGDVGVEIAFAGRSNAGKSSALNALTEQKSLARTSKTPGRTQLINVFELDSQRRLVDLPGYGFAQVPLAMKNKWQQALGEYLQKRACLSGVVVLMDIRHPLKDLDMQMIEWAVASEIPVLALLTKSDKLAQSAKMKTVNEVRKALADFGDWVLVEPFSALKGTGKPKVLSILNEWCHPQWLRDELDTAEQSN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: YURM_BACSU
Sequence: MLPQKKTDSFRLEPVPDQHIEVKDKPRRKWYIGETSVWVFLFLYLIAIAYPLLWMVMSAFKNSDDIFEHSWSLPSSWHPENFVSAWNQGISSYFMNSVIVTALTCVITVFISAWAAYGLSRFEFKGKGFFLVLCLGGLMLTPQVSLVPLYSIIQSLGLYNTYWALILPYAAYRIPFTIILIRSYFLSISKELEEAAYLDGCTSFGVFFRIFLPMSVPILVTSGILTAYHTWNEFMFAIIFIDDENLRTIPAGLMQFRDALQTDWGVLLAGLTISAAPIIILFLLMQKYFVRGIASGSVKG
What is the function of this protein?
Probably part of the binding-protein-dependent transport system YurMNO.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable ABC transporter permease protein YurM.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GREA_STAHJ
Sequence: MENQKQYPMTQEGYEQLEKELEELKTVKRPEVVEKIKVARSFGDLSENSEYDAAKDEQGFIEQDIQRIEHMLRYALIIEDTGDNNVVQIGKTVTFIELPGDEEESYQIVGSAEADAFNGKISNESPMAKALIGKSLKDEVRVPLPNGGEINVKIVNIK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: TGAS_STRCJ
Sequence: MHKRRRLLAFATVGAVICTAGFTPSVSQAASSGDGEEKGSYAETHGLTADDVESINALNERALTLGQPGKPPKELPPSASAPSRAPSDDRETPPAEPLDRMPEAYRAYGGRATTVVNNYIRKWQQVYSHRDGKKQQMTEEQREKLSYGCVGVTWVNSGPYPTNRLAFASFDENKYKNDLKNTSPRPDETRAEFEGRIAKGSFDEGKGFKRARDVASVMNKALENAHDEGTYINNLKTELTNNNDALLREDSRSNFYSALRNTPSFKERDGGNYDPSKMKAVIYSKHFWSGQDQRGSSDKRKYGDPEAFRPDQGTGLVDMSKDRSIPRSPAKPGEGWVNFDYGWFGAQTEADADKTTWTHGDHYHAPNSDLGPMHVHESKFRKWSAGYADFDRGAYVITFIPKSWNTAPAKVEQGWP
What is the function of this protein?
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase, Transglutaminase, TGase.
What is the protein family that this protein belongs to?
Belongs to the bacterial TGase family.
Protein: MTHFS_RABIT
Sequence: AAAAAVSGAKRSLRAELKQRLRAISAEERLRCQRLLTQKVIAHRQYQKSQRISIFLSMPDEIETEEIIKDIFQQGKVCFIPRYRLQSNHMDMVKLASADEISSLPKTSWNIHQPSESDTREEALATGGLDLIFMPGLGFDRNGNRLGRGRGYYDTYLQRCLQQQGAKPYTIALAFREQICPQVPVDDTDVSVDEVLYVDAA
What is the function of this protein?
Contributes to tetrahydrofolate metabolism.  Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.  Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10-methenyltetrahydrofolate.  It can also use 5-formyltetrahydropteroic acid (5-CHO-H(4)Pte) and 5-formyltetrahydropteroylhistidine (5-CHO-H(4)PteHis) as substrate.
What are the official names of this protein?
5-formyltetrahydrofolate cyclo-ligase, 5,10-methenyl-tetrahydrofolate synthetase, MTHFS, Methenyl-THF synthetase.
What is the protein family that this protein belongs to?
Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSBP1_RAT
Sequence: MAETDPKTMQDITLVVETLLQQMQDKFQIMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELDAENKIPTAQKS
What is the function of this protein?
Negative regulator of the heat shock response.  Negatively affects HSF1 DNA-binding activity.  May have a role in the suppression of the activation of the stress response during the aging process (By similarity).
What are the official names of this protein?
Heat shock factor-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the HSBP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NR6A1_XENTR
Sequence: MDTWEDDRVDQRACLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISDEEIERIMSGQEFEEEANTSWSNNGDSDHSSPGNGVSESNQPSPVSTPSSSRSMELNGFGSLRDQYLGTPGPMHYQYLPHLFSYSAHPTLIPTQSRSLDPQSHTLINQLLTAEDIEPLSTPMLIEDGYKVTQSELFALLCRLADELLFRQITWVKKLPFFCDLSIKDYTCLLSTTWQELILLSSLTTYSKQIFGDLADVTSKYSPSEDELHRFSEDGMEVMERLIYLFRKFSQLKVSNEEYVCMKAINFLNQDIQGISSVSQVEQLNKRYWYVCQDFTEYRYPHQPNRFPDLMMCLPEVRYIAGKLVNVPLEQLPLLFKAFLHSCKTSLTKE
What is the function of this protein?
Probable orphan nuclear receptor.  Binds to a response element containing repeats of the motif 5'-AGGTCA-3'.  Required for anterior-posterior patterning during organogenesis.  Acts with chordin to play a role in patterning the midbrain-hindbrain.  Isoform Em is required for integrin-mediated cell matrix interaction during neurulation and for the morphogenetic movements leading to formation of the neural tube.  Also mediates the effect of retinoic acid on primary neurogenesis (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 6 group A member 1, Germ cell nuclear factor, GCNF.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YWQ1_CAEEL
Sequence: MLQKEHASALEKLRVIWLHKKKIEAELQSRHAESTKFLSKIKLKESEIYGLKTKQETCQKELTDCQTLKEEPKEQKKENNKNDENSKKTIEKYEQEIAGLKEKIEGLEEKVKNNYSDENSSLKEELKQCETRIRQLTGGGAIEHYSQNETAHFSRNQKADEPLFFDRGNIQHHIPQKLLLGRELVQTLEEAKVKKLEEREQMDKHPQDRDNKDKEVNEQPDNEEQDYKEH
What are the official names of this protein?
Uncharacterized protein B0286.1.
Protein: LACG_STRSV
Sequence: MTKSLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWYTAEPASDFYHKYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGEVNPKGVEFYHNLFAECHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVNYAAFCFEEFPEVRYWTTFNEIGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHALPTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDVTLAGVNHILKVNGGQLDLRDEDFAALEAAKDLNDFLGINYYMSDWMRDFDGETEIIHNGKGEKGSSKYQIKGVGRRESPTHIPKTDWDWIIYPQGLYDQIMRIKKDYPNYKKIYITENGLGYKDEFVDNTVYDDARIDYVKQHLEVLSDAIVDGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERYPKKSAHWYKKLAETQMIE
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: CTU1_YARLI
Sequence: MLCVLCECRKAMLKRPKTLQPICKPCFYNVFETEIHNTIVESNLFFPGERVAIGASGGKDSTVLAHVMKTLNERYNYGVDFVLLSIDEGIHGYRDDSLETVKRNKVQYDMDLEVVSYSELYGWSMDQIVAQIGNKNNCTYCGVFRRQALDRGSAKLGIAHIVTGHNADDMAETVLMNLLRGDTARLDRCTELVTGSDDSPVKRSKPLKYAYEKEIVLYAHYKKLDYFSTECTYSPEAFRGTARTLIKNLEAIRPSTIIDIIHSGEAFVLKKKKEKKGKGSVVVKAKVEEKPVPSGGCSVPLAFDSSLGLSNRCTKCGYLSHNAVCKACVLLEGLNAGRAKMQIEGDSADGAAKNIKTLEKLALSI
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_LACP3
Sequence: MGKFTVLNHPLIQHKLTLIRDKHAGTKEFREIANEIAELMVYEITRDLPLESIEIETPMGKTIQKQLAGKKLAVVPILRAGLGMVDGVLRLIPAAKVGHIGMYRDEKTLKPHEYFVKMPPDIEQRDLIIVDPMLATGGSANMAIEALKKRGATSMRLVVLVAAPEGVKAVQAANPDVDIYAAALDDHLNENGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SECA_SALPC
Sequence: MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELKAKTNEFRARIEKGESVESLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKKVNKIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYSPGNIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTANGQPVLVGTISIEKSEVVSRELTKAGIKHNVLNAKFHANEAGIVAQAGYPAAVTIATNMAGRGTDIMLGGSWQAEVAALEAPTEEQIAQIKADWQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSDTINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLEMPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEMQRREEAERLAQMQQLSHQDDDAAVAADLAAQTGERKIGRNDPCPCGSGKKYKQCHGRLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: APAH_THISH
Sequence: MSIYAVGDLQGCLTPLKRLLEQVRFDPAADQLWLVGDLVNRGPESLEALRFVRDLGDAAITVLGNHDLHLLAIHQGVHKVRRKDTVQPILDAPDRAELMDWLRHRPLLHHDPRIQWTLLHAGLPPQWDLAMARACASEVETVLRGPDHPTLLERMYGDEPDQWSESLQGWARLRFITNCFTRLRYCTADGSVDMAYKGAPGGQLPHLMPWFAVPGRRSVGTRIVFGHWSTLGLYQGDDVLCLDTGCVWGQRMTLARLDSSALETMHTRCE
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: QUEF_BRASB
Sequence: MAKRSIKSETSPELQLGRPVTAPDSPETARLDRVPNPQKDTDYLARFTVPEFTSLCPVTGQPDFAHLVIDYAPGPWLVESKSLKLYLASFRNHGAFHEDCTVAIGKRLATELKPKWLRIGGYWYPRGGIPIDVFWQTGKLPKGLWVPDQGVAPYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_SHIDS
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y4205_KORVE
Sequence: MIEIRETSSGVSFAVRLQPKAKKTAIIGELNGALKLGVTDPPIDGRANEALIRFVAGLLKVTRSSVTIAAGESSRNKVIRIEGVTAEQVRFRLKVW
What are the official names of this protein?
UPF0235 protein Acid345_4205.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: TRM56_METBU
Sequence: MQKIVILRLGHRPERDKRITTHVGLTARALGAEGMLLASNDKGIKNAIEDVAERWGGDFYVENDVNWKSEIEKWKEEGGKVCHLSMYGINLPDAAGEIKLCDKLMIVVGAEKVPTEIYDLADWNVAIGNQPHSEVAAVALTMDRIAQEEPLKREFGYAELTIVPMERGKRVINNVKEE
What is the function of this protein?
Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
What are the official names of this protein?
tRNA (cytidine(56)-2'-O)-methyltransferase, tRNA ribose 2'-O-methyltransferase aTrm56.
What is the protein family that this protein belongs to?
Belongs to the aTrm56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_SYNWW
Sequence: MDNNRIGEVQRKTSETEVLLQVELDGTGNHQIDTEIPFLNHMLTLFSFHSLCNLRVTARGDVEVDDHHSVEDIAICLGQALKMALGDKRGITRYGEATVPMDESLARVVLDLSGRSYLVYNVPMEREMIGNFATENVREFFQAVAANAGINIHIDLLRGSNTHHIIEAVFKAFARALKDAIEIEPRMEGIWSSKRVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_SULNB
Sequence: MSRRCSVSGKGPLVGNNVSHANNKTKRRQLPNLRSVKITMEDGTTKRVKVAASTLRTMKKKAAQAAAAN
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CEA16_HUMAN
Sequence: MALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAPLG
What is the function of this protein?
Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.
What are the official names of this protein?
Carcinoembryonic antigen-related cell adhesion molecule 16, Carcinoembryonic antigen-like 2.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. CEA family.
What are the subcellular locations of this protein?
Secreted. Note=Localizes to the tip of cochlear outer hair cells and to the tectorial membrane.
Protein: AB17C_CHICK
Sequence: MPEQGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLPPEQQQEAGAASGAATPTGSGTCSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPTGRYTLLFSHGNAVDLGQMCSFYIGLGSRINCNVFSYDYSGYGVSTGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins.  Has depalmitoylating activity towards NRAS.
What are the official names of this protein?
Alpha/beta hydrolase domain-containing protein 17C, Abhydrolase domain-containing protein 17C.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD17 family.
What are the subcellular locations of this protein?
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendritic spine. Postsynaptic density membrane.
Protein: CBID_METKA
Sequence: MNDLLDPIRGIPVDLELVRRELDVDLPTARYLVRTGLITTDGARVLRRGPTTGTCATAAAKAAAIRLLEGRTVRTVRVRLPVGTVIGVRISRVGGDPSEARVRKPGSDDHVDVTTGVTIAARVEETGSEGVEIRAGRGVGETPSGKPAISEAVREQIVDNLRYLVDSYGVGLRVTIEVPDGEEIARKTLAHRHGIEGGISILGTKGLVDPNSEEAIEGSIRSDLRYVERVPCLVTGYRTMDRARRLGIPSRDIVNCHGRYDLALEAVKTGVPADGEVKRFDAVLIFGMPGKLLKLAAGAYNTHAKVADARRESLVTRLVEIGRPDLAVEAARHEGLISEFLRSLDPDVRRELFERVCELVEERVSSDHDLECGCALYFRADDSEEVVEGEGWKRLVRGYDDDLIGRPKG
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: PSBT_LACSA
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.