PharMolix/UniProtQA huggingface dataset:
Protein: KEX1_YEAS2
Sequence: MFYNRWLGTWLAMSALIRISVSLPSSEEYKVAYELLPGLSEVPDPSNIPQMHAGHIPLRSEDADEQDNSDLEYFFWKFTNNDSNGNVDRPLIIWLNGGPGCSSMDGALVESGPFRVNSDGKLYLNEGSWISKGDLLFIDQPTGTGFSVEQNKDEGKIDKNKFDEDLEDVTKHFMDFLENYFKIFPEDLTRKIILSGESYAGQYIPFFANAILNHNKFSKIDGDTYDLKALLIGNGWIDPNTQSLSYLPFAMEKKLIDESNPNFKHLTNAHENCQNLINSASTDEAAHFSYQECENILNLLLSYTRESSQKGTADCLNMYNFNLKDSYPSCGMNWPKDVSFVSKFFSTPGVIDSLHLDSDKIDHWKECTNSVGTKLSNPISKPSIHLLPGLLESGIEIVLFNGDKDLICNNKGVLDTIDNLKWGGIKGFSDDAVSFDWIHKSKSTDDSEEFSGYVKYDRNLTFVSVYNASHMVPFDKSLVSRGIVDIYSNDVMIIDNNGKNVMITTDDDSDQDATTESGDKPKENLEEEEQEAQNEEGKEKEGNKDKDGDDDNDNDDDDEDDHNSEGDDDDDDDDDDDDDDDDDEDDNNEKQSNQGLEDSRHKSSEYEQEEEEVEEFAEEISMYKHKAVVVTIVTFLIVVLGVYAYDRRVRRKARHTILVDPNNRQHDSPNKTVSWADDLESGLGAEDDLEQDEQLEGGAPISSTSNKAGSKLKTKKKKKYTSLPNTEIDESFEMTDF
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from the precursors of K1, K2 and K28 killer toxins and a-factor (mating pheromone).  Involved in the programmed cell death caused by defective N-glycosylation and contributes also to the active cell death program induced by acetic acid stress or during chronological aging.  Promotes cell fusion by proteolytically processing substrates that act in parallel to PRM1 as an alternative fusion machine, as cell wall components, or both (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D, Killer expression defective protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: YAP1_SCHPO
Sequence: MEQIRPFSDNYLDRLRTVEEDDYNDWEGSSDTKTLYSSVSDSKIGHKKSFHKDGKGLFKTLRNFLSLKTNKVPKNRKFSLLKGSKCNNVEIKVFIRNNDKQSNVHNFKGKDSIHEAWSQYLIFDSMGLSPLIHISGEDKYKVLCLFSIWRRKLGKCSIFTVHDPDIQKKIKSILSYLWELSNTNDPPHVIVWHTAKGTNVMTMGPLGLKDEDLWNYANERSNLNGTT
What are the official names of this protein?
Uncharacterized protein C15F9.01c.
Protein: MCM5_ORYSJ
Sequence: MSGWDEGAVFYSDQAQFPRGGPGGDPSADLTRHSALRKFKEFLRGFTGPTGDFPYRESLVHNRDHVTVAIEDLDAFDAELSDKIRKSPADYLPLFETAASEVLASLRSKVAGETGEMEEPATGDVQIFLSSKENCLSMRSIGADYMSKLVKIAGITIAASRVKAKATHVTLLCKNCRSVKTVPCRPGLGGAIVPRSCDHVPQPGEEPCPLDPWIAVPDKSKYVDLQTLKLQENPEDVPTGELPRNMLLSVDRHLVQTIVPGTRLTVIGIYSVYQASANQKGAVGVKQPYIRVVGLEQSRDANSNGPSNFTLDEEMEFKEFAQRPDAYVKICSMIGPSIYGHSDVKKAIACLLFGGSKKRLPDGVRLRGDIHVLLLGDPSTAKSQFLKFVEKTAPIAVYTSGKGSSAAGLTASVIRDGSSREFYLEGGAMVLADGGVVCIDEFDKMRPEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIAGRYDDLKTAQDNIDLQTTILSRFDLIFIVKDVRMYDQDKRIASHIIKVHASGAAASSKNTDASEGENWLKRYIEYCRVTCKPRLSEKAAEMLQNKYVEIRQKMRQQAHETGRAAAIPITVRQLEAIIRLSESLAKMRLTSVATPEHVEEAFRLFNVSTVDAARSGINEHLNLSPDIANEIKQAEAQIKRRMGIGSHISERRLIDELNRMGMNESIVRRALLIMHQRDEVEYKRERHVIVRKA
What is the function of this protein?
Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.
What are the official names of this protein?
DNA replication licensing factor MCM5, Minichromosome maintenance protein 5, OsMCM5.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: H2AB1_HUMAN
Sequence: MPRRRRRRGSSGAGGRGRTCSRTVRAELSFSVSQVERSLREGHYAQRLSRTAPVYLAAVIEYLTAKVPELAGNEAQNSGERNITPLLLDMVVHNDRLLSTLFNTTTISQVAPGED
What is the function of this protein?
Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing (PubMed:22795134).  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability (PubMed:15257289, PubMed:16287874, PubMed:16957777, PubMed:17591702, PubMed:17726088, PubMed:18329190, PubMed:22795134).  Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo (PubMed:15257289, PubMed:16957777, PubMed:17591702, PubMed:24336483).  They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase (PubMed:17591702, PubMed:24753410).  They associate with spliceosome components and are required for mRNA splicing (PubMed:22795134).
What are the official names of this protein?
Histone H2A-Bbd type 1, H2A Barr body-deficient, H2A.B, H2A.Bbd.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with the active X chromosome and with autosomes, while it is absent from the inactive X chromosome and excluded from Barr bodies.
Protein: HERC5_HUMAN
Sequence: MERRSRRKSRRNGRSTAGKAAATQPAKSPGAQLWLFPSAAGLHRALLRRVEVTRQLCCSPGRLAVLERGGAGVQVHQLLAGSGGARTPKCIKLGKNMKIHSVDQGAEHMLILSSDGKPFEYDNYSMKHLRFESILQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQLGNGGTRDQLMPLPVKVSSSEELKLESHTSEKELIMIAGGNQSILLWIKKENSYVNLKRTIPTLNEGTVKRWIADVETKRWQSTKREIQEIFSSPACLTGSFLRKRRTTEMMPVYLDLNKARNIFKELTQKDWITNMITTCLKDNLLKRLPFHSPPQEALEIFFLLPECPMMHISNNWESLVVPFAKVVCKMSDQSSLVLEEYWATLQESTFSKLVQMFKTAVICQLDYWDESAEENGNVQALLEMLKKLHRVNQVKCQLPESIFQVDELLHRLNFFVEVCRRYLWKMTVDASENVQCCVIFSHFPFIFNNLSKIKLLHTDTLLKIESKKHKAYLRSAAIEEERESEFALRPTFDLTVRRNHLIEDVLNQLSQFENEDLRKELWVSFSGEIGYDLGGVKKEFFYCLFAEMIQPEYGMFMYPEGASCMWFPVKPKFEKKRYFFFGVLCGLSLFNCNVANLPFPLALFKKLLDQMPSLEDLKELSPDLGKNLQTLLDDEGDNFEEVFYIHFNVHWDRNDTNLIPNGSSITVNQTNKRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDIIKLFHPEELKDVIVGNTDYDWKTFEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMKITFCCPESWNERDPIRALTCFSVLFLPKYSTMETVEEALQEAINNNRGFG
What is the function of this protein?
Major E3 ligase for ISG15 conjugation.  Acts as a positive regulator of innate antiviral response in cells induced by interferon.  Functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner.  Catalyzes ISGylation of IRF3 which results in sustained activation, it attenuates IRF3-PIN1 interaction, which antagonizes IRF3 ubiquitination and degradation, and boosts the antiviral response.  Catalyzes ISGylation of influenza A viral NS1 which attenuates virulence; ISGylated NS1 fails to form homodimers and thus to interact with its RNA targets.  Catalyzes ISGylation of papillomavirus type 16 L1 protein which results in dominant-negative effect on virus infectivity.  Physically associated with polyribosomes, broadly modifies newly synthesized proteins in a cotranslational manner.  In an interferon-stimulated cell, newly translated viral proteins are primary targets of ISG15.
What are the official names of this protein?
E3 ISG15--protein ligase HERC5, Cyclin-E-binding protein 1, HECT domain and RCC1-like domain-containing protein 5.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Note=Associated with the polyribosomes, probably via the 60S subunit.
Protein: RS19_TRIEI
Sequence: MSRSLKKGPFIADHLLKKIEALNAKNEKQVIKTWSRSSTIIPDMVGHTIAVHNGRQHVPVFISDQMVGHKLGEFAPTRTYRGHGSDKKSKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: BUT79_GIBZE
Sequence: MAMFTVLPLIWLAPLGLISLFFYYIIPYFWNYRHLRSIPGPLFARLSNWWLVYACREKSRWKYVNDAHTRYGPVVRIQPNHVSIANEEVINAIYGHGNGMLKSSFYDASVITTYSIFTSRDRAEHSRKRKVVSHSFAPQSMRNFEPFIQQHLNVFLQKWDAMAANEAKFDGYADVESRVWLNYLVLDIIGDLAFGAPFGVLAKGSEVVDFETEKGPSSLPVITSLSTRSEIAATVGALPELKPYLKWSPDPFFRTGFNGMINLRTLGTSRITDRLNNPPGDEREKDLLERVREGRDHKGQPFGKGELIAEALTVLIAGTDTTSSTMAALLYHVVRTPGVLKKLQAELDEAIPADVSIPSFEMVKNLKYLGFVVNEALRHHSTISLGLPRLVPENGNGVTIAGYHFAPGTVLSIPIYTVHHLKEVWGPDADEFKPERWEDVTQRQKQAFIPFSHGPRACLGRNLAEMELKVITATWARRYDLIMRDDTMEILEGLARKPEAVNVGIRRRM
What is the function of this protein?
Cytochrome P450 monooxygenase FG08079; part of the gene cluster that mediates the biosynthesis of butenolide, a mycotoxin that shows antibiotic activity but does not seem to play a major role in the spread of head blight in wheat (PubMed:17175185).  Butenolide is derived from glutamic acid via a 4-acetamido-2-butenoic acid intermediate (Probable).  The predicted function of the NADH:flavin oxidoreductase FG08077, the cytochrome P450 monooxygenase FG08079, the decarboxylase FG08083, and the putative acetyltransferase FG08082 are consistent with this pathway, however, the respective activities of the butelonide biosynthesis cluster enzymes have still to be experimentally determined (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase FG08079, Butenolide biosynthesis cluster protein FG08079.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NUOK_LEPBP
Sequence: MNQIINGIPVTYILGLAGILFSIGVLGVLIRRNIVIIFMSVELILNSVNLVFVTFSKALSHINGETIVFFVMAIAAAEAAVGLALVIAIFRHKKSTNVDELQSMKW
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRI_VIBCH
Sequence: MSKETKLQVEAIKNGTVIDHIPAKVGIKVLKLFDMHNSAQRVTIGLNLPSSALGSKDLLKIENVFISEAQANKLALYAPHATVNQIENYEVVKKLALQLPERINNVFACPNSNCISHNEPVESSFKLSEKNNDIRLKCKYCEKVFARDVVTEIEA
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: CY550_VIRHA
Sequence: GGSVDSAAAEEVFESNCASCHGADLSGAGPDLTQV
What is the function of this protein?
Monoheme cytochrome which functions as an electron carrier in the reduction of nitrite by membrane vesicles.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550.
Protein: Y991_METJA
Sequence: MVIIMPTKTITLKVPSNISKKKIEEAIKKLELEEKYKKTENFKLFVKDEDLKMKIYKIAEFVEDYLKKKYSDEEFEIVLDYDGIDDKVVVEIVFKKKLDKRELKDIKVIIRKLKEIIFDAWRKVDEKYPDMRGFLIVTSDLEVL
What are the official names of this protein?
Uncharacterized protein MJ0991.
Protein: PNP_RENSM
Sequence: MEGPEIQFSEAVIDNGRFGKRTIRFETGRLAQQAAGAAMVYIDDDTALLSATTAGKQPREGFDFFPLTVDVEERMYAAGRIPGSFFRREGRPSTEAILACRLMDRPLRPAFVKGLRNEVQIVVTVLAINPDELYDVVAINASSMSTQLSGLPFSGPIGGVRVALIEDQWVAFPRHSEMEKAVFNMVVAGRVAGDDVAIMMVEAEATDNSWNLIKENGATAPTEEIVSEGLEAAKPFIKALCEAQADLAARAAKPTVEFPIFLDYQDDIFEAVNAAAAAKLTEVFQIADKQERDNASDALKDEVVSSLSSKFDGREKEISAAFRSVTKQVVRQRILKDQIRIDGRGLTDIRQLTAEVEVLPRVHGSAIFERGETQIMGVTTLNMLKMEQQIDSLSPVTRKRYMHNYNFPPYSTGETGRVGSPKRREIGHGALAERALVPVLPSREEFPYAIRQVSEALSSNGSTSMGSVCASTLSLLNAGVPLKAPVAGIAMGLVSDQVDGQTRYAALTDILGAEDAFGDMDFKVAGTSEFVTAIQLDTKLDGIPASVLAAALKQAREARLHILGVLNAAIDVPDELSEFAPRVIAVKIPVDKIGEVIGPKGKMINQIQEDTGADISIEDDGTVYIGATNGPSADAARSAINAIANPQIPEIGERYLGTVVKTTTFGAFVSLTPGKDGLLHVTELRKINDGKRVDNVDDVVSVGQKIQVEITKIDDRGKLSLSPVVAEDAAAADSAEAAEPAEAAAN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAL1_SHIDS
Sequence: MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKHLQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKHVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGGGFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGT4E_MOUSE
Sequence: MEGGLRTGRLPKAPELSLQSFPSEWSWVWTYPLFHKLAAFACHASQAWLTVGITSESREGPNGLLDTLASLYHTSSTSEQKQMTVLVHLADSDPTWLRRTIIRISSLYRSQILTGQLLLIHAPPDAYPAVNDAQNKVSRGQIYSKQNVDHAFLMSFATKLSTYFLLIEDNVFCAPNFVNHIRSKVGYRKPNTWVLLEFSNMGFLGKLLHSRDLPLLAHFLLLFHKERPLNWLLLHFRTLLGQQSSILCRPFLFYHRLTHLTFENKTLIGHEKDPPDPYTLSGTVYTDMRFSDTHSPQEAYTLDESFFWSYNVTTGNYLTVILNNPANLNRVQVRTGSITDGKYILEKGQVELGYDPEGTPPQCTSFTLLGRLVQGQMDQFILESIGYKVSCVKLAVNANQVGGLMIRHIYIWGENAKNRKDVQIDNDDDDDDDDYDDDS
What is the function of this protein?
Glycosyltransferase-like protein that may participate in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans.
What are the official names of this protein?
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4E.
Protein: CAPP_HAEIN
Sequence: MTQEYSTLRNNISMLGRFLGETINDAQGEDILELIENIRKLSRNSRAGDDKARQALLDTLGSISNENIIPVARAFSQFLNLTNIAEQYQTISREHSLAQSSSQSLSELFKRLKEQNASVEEVHKTVEKLLIELVLTAHPTETTRRSLIHKHIEINKCLSKLEHHDLTEKERNIIERLLLRLIAEAWHTNEIRTVRPTPFDEAKWGFAMLENSLWQAVPEFLRQLNETAREFLGYDLSVGLKPVRISSWMGGDRDGNPFVTAQITKKVLYFARWKAADLFLQDISKLADELSMMKCSDEFRDKYGEHLEPYRFVVKNLRNQLTATLAYFDDHLSNRTPRVSESEIILEDNQLWEPLYDCYQSLIQCGMRIIANGSLLNILHRISCFGVTLSQMDIRQESTRHTDAIAEITRYIGLGDYSQWMEDDKQAFLIRELSSRRPLIPQNWTPSPETKEILDTCKVIAQQKQGVIACYVISMARSASDVLAVHLLLKESGVPYHIPVVPLFETLEDLDAAEKVMTQLFNVGWYRGVINNRQMVMIGYSDSAKDAGMMAASWAQYRAQEALVNLTEKLGIELTLFHGRGGTIGRGGAPAHAALLSQPPRSLKNGLRVTEQGEMIRFKLGLPAVAVETFDLYASAILEANLLPPPEPKPEWRTIMDELSTISCDIYRGVVRGDKDFVPYFRSATPEQELSKLPLGSRPAKRNPNGGVESLRAIPWIFAWMQNRLMLPAWLGAGAAIRQVIEQGKGDIIHKMCENWPFFSTRIGMLEMVFSKSDTWLSQQYDQRLVKKELWYLGENLRKQLEDDIQTVLSLSHQSELMSDLPWIADSIALRNIYTDPLNLLQVELLHRFRENPEQVNPDVEQALMITITGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: ATPI1_ACTTE
Sequence: MARTASTILFLLCLVLITGYTMARQEHCNLPLEKGKCGGRFERFYYNSHKGKCESFFYGGCSGNDNNFENEEECDKACGAFMTMADANSFCNLPAVVGRCKGYFPRYFYNTEAGKCQRFIYGGCGGNRNNFETVXDCRATCHPREKRALADMTMADANSFCQLPAVVGRCRGRFPRYYYNTEAGKCQRFIYGGCXGNRNNFETVEDCRATCHPREKRALADMTMADANSFCQLPAVVGKCRGYFPRYYYNTEAGKCQQFIYGGCGGNRNNFETVEDCRATCHSHA
What is the function of this protein?
May be involved in regulating functions and processes within the digestive system (Probable).  Shows serine protease inhibitory activities (PubMed:31842369).  Strongly inhibits trypsin (Ki=0. 08 nM), chymotrypsin (Ki=2. 9 nM), and kallikreins (KLK5, KLK7 and KLK14) (PubMed:31842369).
What are the official names of this protein?
Actinia tenebrosa protease inhibitors, Carboxypeptidase inhibitor SmCI-like.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: CD38_HUMAN
Sequence: MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI
What is the function of this protein?
Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion (PubMed:8253715, PubMed:7961800).  Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid.  At both pH 5. 0 and pH 7. 4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+) (PubMed:16690024).  Has cADPR hydrolase activity (PubMed:8253715, PubMed:7961800).
What are the official names of this protein?
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, ADPRC 1, Cyclic ADP-ribose hydrolase 1, cADPR hydrolase 1, T10.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: ARLY_SHEAM
Sequence: MALWGGRFQGQASALFQLFNDSLPVDYRLFVQDVEGSIAWADAIASVGILNADECSRLKAALTELLEEVGEDESAIIGSGAEDIHSFVETKLIEKVGDLGKKLHTGRSRNDQVATDLKLWCKASGGLLETKLTAVIQALLALASRELDAVMPGYTHLQRAQPVTFGHWCLAYVEMLERDLSRLADALKRLNTCPLGSGALAGTAYAIDRHELAAALGFGGPTLNSLDSVSDRDHVVELCAAASVSMMHLSRMAEDLIFFNTGEAAFVELADNVTSGSSLMPQKKNPDALELIRGKTGRVYGNLVGILTTMKALPLAYNKDMQEDKEGLFDTLDSWGICLDMAALVLEGVKVNRDNTKQAAQAGYANATELADYLVAKGMPFREAHHVVGEVVLHAISKGQALEALPLASLQSFAAVIGDDVYPHLSLDECLAKRDVLGGTAIKQVTAALAAKQQQY
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3H9_ORYSJ
Sequence: MQEALVSPVRSALELKPFNFGDQRLASSPRYLPSGDDALYRCSSPFSPSFGFSSPSPLATSVSLSPSSSASLVDDGDDGGAAADATGQRLQLARLALQYQEVADRYELCLSHLAEAAEEAAALRLENAELRVTNSDLALRLALLSGKHTAAVAVADEIRRLRLGEQKVAAATKERTPEKLAVLPKSISVRSTSYLKLNQQSQAATATSAAPNRKPRTSSNPTNPPNSQRAYDGGKKGDEQKAQPADSGAELEVYNQGMFKTELCNKWEETGDCPYGDQCQFAHGVTELRPVIRHPRYKTAVCRMVLAGDVCPYGHRCHFRHSLTPAERLLLRS
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 9, OsC3H9.
Protein: DAPF_BURTA
Sequence: MKLSFTKMHGAGNDFVVLDGYSRALPPLTDALVRALADRHFGIGADQLLLVEKPTVDGADFKYRIFNCDGGEVEHCGNGARCFVKFVRDHGLTDKASVRVEVKHGVITLTMQDNGEVVVDMGAPVFEPARVPFDTSGLDGRREGADTLWPLPVNGATRWISVVSMGNPHAVQIVDDAEAFPVLADGPAIERDPRFPQRVNAGFMQIVSRHEVKLRVYERGAGETLACGTGACAAVAAGIRRGQLDSPVTVHTHGGTLTISWDGARDERAPLMMAGPATTVFEGVIDLPA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF73_ORYNI
Sequence: MVLISATRDFRERTKSKLVKIMIWAGIVVITFAIAVRIYPIFIFLLKERIKPLVEALYDKLPWIWEVSLSRYWDRLIDFLDRYLWACAQRIQTGIRKQKGEFVVTFSCRVKKRLYARAIEVGIHLSLLSNLFWILKTTLAVGYRLLWVLYYIISFEGFLGSFRLYLVYFGFYCLLFSGKWLRTSEDRGERQAQISGILLRGMLIECAFSVLCLEEDSNLHAL
What are the official names of this protein?
Uncharacterized protein ycf73, ORF222.
What is the protein family that this protein belongs to?
Belongs to the ycf73 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UBIB_PSESM
Sequence: MKLLAVRRLFRIQRVVIRYRLDDLLFALPLPWWMLAVRFVLPWRWLPRRKSELSRGVRFRLALQDLGPIFIKFGQLLSTRRDLLPEDIADELMLLQDRVPPFDQQVAIKLIEEQLGARICDVFSRFDETPLASASVAQVHAACLKTGEEVVVKVVRPGLKPIIGQDLAWLFILARMAERVSADARLLHPVQVVMDYEKTIYDELDLLREAANSSQLRRNFEGSDLLYVPQVYWDWCRPKVLVMERIYGLQVTDMAGLADQRTDMKMLAERGVEIFFTQIFRDSFFHADMHPGNIFVSTVNPWAPKYIAIDCGIVGSLTPEDQDYLARNLFAFFKRDYRRVAQLHIDSGWVPAETKLNEFEAAIRTVCEPIFEKPLKDISFGQVLMRLFQTARRFNMEVQPQLVLLQKTLLNIEGLGRQLYPELDLWSTAQPYLERWMRERVSPKTLLGNLQSQVEQLPHIAGMTRDLLERMSRPHASDPPRPWHDRKDEPVLRLIGAALLVGGAIQGWVMSEAATQLLTLTAWPAAIMLIAGLYLIVRR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MAF_DANRE
Sequence: MASELAMSSSDLPTSPLAMEYVNDFDLMKFEVKKEPVEPDRSISQCSRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDFYWMTGYQQQLNPEALGFSPEDAVEALISSSHQLQSFDGYARGQQFGSAAGAGGAMAGEEMGSAAAVVSAVIAAAAAQNGAPHHHHHHHHHHPAGHHHHHAAPGAQSNGASAGHPGHMHLDERFSDEQLVNMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRYKRVQQRHVLEGEKTQLMQQVDHLKQEISRLVRERDAYKEKYEKLISSGFRENGSSSDNNPSSPEFFM
What is the function of this protein?
Acts as a transcriptional activator or repressor.
What are the official names of this protein?
Transcription factor Maf.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Maf subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YOT0_CAEEL
Sequence: MCQILLAILAIFLPPIAVLLDVGCNCDLLINILLTCLGIIPGIIHAWYIILCKEKTVVQNIYVQTNDHGTAPPAYSPYSA
What are the official names of this protein?
UPF0057 membrane protein ZK632.10.
What is the protein family that this protein belongs to?
Belongs to the UPF0057 (PMP3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YCDX_ECO8A
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIAEFADL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: NU6M_CHICK
Sequence: MTYFVIFLGICFMLGVLAVASNPSPYYGVVGLVVASVMGCGWLVSLGVSFVSLALFLVYLGGMLVVFVYSVSLAADPYPEAWGDWRVVGYGLGFVLVVWMGVVLGGLVDFWKVGVVTVDGGGVSFARLDFSGVAVFYSCGVGLFLVAGWGLLLALFVVLELVRGLSRGAIRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.