PharMolix/UniProtQA huggingface dataset:
Protein: EFPL_ECOL5
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: STA5A_MOUSE
Sequence: MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRGQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNCSSPAGVLVDAMSQKHLQINQRFEELRLITQDTENELKKLQQTQEYFIIQYQESLRIQAQFAQLGQLNPQERMSRETALQQKQVSLETWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNISSNHLEDYNSMSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPDRNLWNLKPFTTRDFSIRSLADRLGDLNYLIYVFPDRPKDEVFAKYYTPVLAKAVDGYVKPQIKQVVPEFVNASTDAGASATYMDQAPSPVVCPQPHYNMYPPNPDPVLDQDGEFDLDESMDVARHVEELLRRPMDSLDARLSPPAGLFTSARSSLS
What is the function of this protein?
Carries out a dual function: signal transduction and activation of transcription.  Mediates cellular responses to the cytokine KITLG/SCF and other growth factors.  May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.  Binds to the GAS element and activates PRL-induced transcription.  Regulates the expression of milk proteins during lactation.
What are the official names of this protein?
Signal transducer and activator of transcription 5A, Mammary gland factor.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
Protein: RL28_SULDN
Sequence: MAKKCAISGKGPMSGNNVSHAKNRTKRRFLLNLRTVRIALDDGTTRKIKISARELRTLKKNS
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: AT53_TOXGO
Sequence: MESTEATMVERKAESPSSGDRARSIELAHQPTGAGASLSSFEVGGAKQGVNKAQDSAVNKGAANTPPRVAFGLSRYVVLVAYCLYCLLSGPSFMNWTTIADSLYKSGAFEWECKPGEIDTSVLPHEPKCPEQEVSVNHLFTVASCSYFVFAMLGGIMLDFAGPKFGALTGLACLITGWTLFGFSSESFRAYVPAMVFMGAGIDMAFFPCLCGANLFPGMVATIIAVYGSFRSISFIVGLSLRTIYINVEGATFRGVMLGYVGAGLGFCLLVALFIIPRRAWPAPDEAPSASAEQDVEAGADALAQKGEKNLTAIQSMKRDFLSLSFLPLFPYFVLVLITILFFAPSAKRLIPSAYEANQIISIFSFVPCIILGGIADRLGIVPVMMICNTCGLLSWILMLIPGIPCFAASQYIVSILISIQMSFLVSQVYCYVTEIFYPENLGKMIGFLCSVGGIISLVTDPMRKYSVDNGFYTMTVLCLIFALINEGLLLFMYVRKRKVPKVL
What is the function of this protein?
L-tyrosine transporter that is essential for parasite survival and virulence (PubMed:30742695).  May also act as an aromatic and large neutral amino acid transporter (PubMed:30742695).  Does not cotransport other charged ions (PubMed:30742695).  Involved in amino acid homeostasis by facilitating the net uptake of L-tyrosine and maintaining intracellular pools of aromatic and large neutral amino acids through exchange (PubMed:30742695).
What are the official names of this protein?
Aromatic and large neutral amino acid transporter 5-3, Apicomplexan amino acid transporter 5-3, TgApiAT5-3, Major facilitator superfamily domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the SLC43A transporter (TC 2.A.1.44) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NIP23_MAIZE
Sequence: MAASTTSRTNSRVNYSNEIHDLSTVQGGSAAAAAAALFYPDSKSIADIFPPHLGKKVISEVVATFLLVFVTCGAASIYGEDNARISQLGQSVAGGLIVTVMIYATGHISGAHMNPAVTLSFACFRHFPWIQVPFYWAAQFTGAMCAAFVLKAVLQPIAVIGTTTPSGPHWHALAIEIVVTFNMMFVTCAVATDSRAVGELAGLAVGSAVCITSIFAGPVSGGSMNPARTLAPAVASNVFTGLWIYFLGPVVGTLSGAWVYTYIRFEEAPAAAKPDTQRLSSFKLRRMQSQSALAADEFDTV
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin NIP2-3, NOD26-like intrinsic protein 2-3, ZmNIP2-3, ZmNIP2;3.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ANT3_HUMAN
Sequence: MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
What is the function of this protein?
Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade (PubMed:15853774, PubMed:15140129).  AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa (PubMed:15140129).  Its inhibitory activity is greatly enhanced in the presence of heparin.
What are the official names of this protein?
Antithrombin-III, ATIII, Serpin C1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RLMH_ALKCK
Sequence: MNITILSVGKLKEKYIKQGIDEYKKRLSAYAKIQEIEVPDEKAPEHLSTEDMRLVKKKEGERLLAKISADSYVIALAIEGNMKTSEQLAKNIEQLGTYGKSKIAFIIGGSLGLSNDVYARADELLSFSKMTFPHQLMKLVLFEQLYRSFRIMRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_ENDTX
Sequence: MSLNCKDLLGLEHLGKKDLQTILDSVGPFKSLFTRSVKKVPTLVGKTVVTLFYEPSTRTRNSFEIAAKRLSADVVNVTVNTSSIVKGESLIDTGKTLEAMKADYLIIRHSLAGAPDILARNLNASIINAGDGFHEHPTQGLLDLYTMYEKKKKIEGLKVLLVGDILHSRVAKSNIWALIKMGAEIAVVGPPTLIPSNIEDLGVKVYYDLNEAIKKVDVVNILRIQLERQQENLFPSVHEYVELYQVTEERLAMAKPGVLIMHPGPMNRGIEISSDVADSPNAVINEQVTNGIAVRMAVLCLLKPKRKNASSD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: APT_RUEST
Sequence: MSTSKTVKDYIRTIVDFPHEGIMFRDVTTLFADPRGFRMAVDQMLHPYAGQRIDKVVGLEARGFILGGAIAHQLGTGFVPVRKKGKLPGATISQEYKLEYGEAVVELHKDAIQPGEKILVVDDLLATGGTAGAGIKLIEKLGGEIISCSFIIDLPELGGRKHLQSLGMDVHVLCEFEGL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUGAB_VESVU
Sequence: DRTIWPKKGFSIYWNIPTHFCHNFGVYFKELKQFNIKYNSMNNFRGETISLFYDPGNFPSMVLLKNGTYEIRNEGVPQKGNLTIHLEQFTKELDEIYPKKIAGGIGVIHFHNWRPIFRRNVDNLKINKDISIDLVRKEHPKWDKSMIEKEASNRFETSAKIFMEKTLKLAKEIRKKTEWGYHGYPHCLSGSTDKPSFDCDALSMSENDKMSWLFNNQNVLLPSIYLKNVLKPDEKIHLVQERLKEAIRISKNFKHLPKVLPYWWYTYQDKESIFLTEADVKNTFKEILTNGADGIIIWGVSYELTDRKRCEKLKEYLMKILGPIAFKVTKAVKENTPLNF
What is the function of this protein?
Has no hyaluronidase activity.
What are the official names of this protein?
Inactive hyaluronidase B, Hya B, Hyaluronoglucosaminidase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BKDB_MYCTU
Sequence: MTQIADRPARPDETLAVAVSDITQSLTMVQAINRALYDAMAADERVLVFGEDVAVEGGVFRVTEGLADTFGADRCFDTPLAESAIIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVDMPVTVRIPSFGGIGAAEHHSDSTESYWVHTAGLKVVVPSTPGDAYWLLRHAIACPDPVMYLEPKRRYHGRGMVDTSRPEPPIGHAMVRRSGTDVTVVTYGNLVSTALSSADTAEQQHDWSLEVIDLRSLAPLDFDTIAASIQRTGRCVVMHEGPRSLGYGAGLAARIQEEMFYQLEAPVLRACGFDTPYPPARLEKLWLPGPDRLLDCVERVLRQP
What is the function of this protein?
Component of the branched-chain alpha-ketoacid dehydrogenase (BCKADH) complex, that catalyzes the overall conversion of branched-chain alpha-ketoacids to acyl-CoA and CO(2).
What are the official names of this protein?
3-methyl-2-oxobutanoate dehydrogenase subunit beta, Branched-chain alpha-ketoacid dehydrogenase E1 component subunit beta, BCKADH E1-beta.
Protein: ICAM1_CANLF
Sequence: APALPRLPALLALLGALLPGLGGAQTSVDPAEAIILRGGSVQVNCSTSCNQTSIFGLETLLTKTEVTSGDNWVLFELTDVQEDSKLICFSNCHDETMAPIDLTVYWFPERVELAPLPRWQPVGENLTMTCQVAGGAPRTNLTVVLLRGEEELSRQPAVGEPAEVTFTVAVGREDHLANFSCRTDLDLRHRGLGLFQNSSAPRQLQTFVLPETPPRLATPPIVEVGTQWSVDCTMDGVFPASEAQVHLALAEERLHSTVLYKKDSLLATANVKANPEDEGTQQLWCEVTLGDENRRWQENVTFYSFPAPNLTLSEPEVSEWTTVTVECEAPAGVVVSLSGLPSGLAVPRAQFQLNASAADNRRSFSCSAALEVAGHMLQKNQTRELHVLYGPRLDQRDCPGNWTWEEGFHQTLKCQAWGNPVPELKCHRKGDDALLPIGDLRPVKREVAGTYLCQARSPRGEITREVVINVIYHQNNILIIILVTTIVILGTVSVAAYLYNRQRKIQKYKLQKAQEAAAMKLNTPATPP
What is the function of this protein?
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).  During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity).
What are the official names of this protein?
Intercellular adhesion molecule 1, ICAM-1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. ICAM family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DCD_ESCF3
Sequence: MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRREDAKYRNQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PFKA_CORGL
Sequence: MEDMRIATLTSGGDCPGLNAVIRGIVRTASNEFGSTVVGYQDGWEGLLGDRRVQLYDDEDIDRILLRGGTILGTGRLHPDKFKAGIDQIKANLEDAGIDALIPIGGEGTLKGAKWLSDNGIPVVGVPKTIDNDVNGTDFTFGFDTAVAVATDAVDRLHTTAESHNRVMIVEVMGRHVGWIALHAGMAGGAHYTVIPEVPFDIAEICKAMERRFQMGEKYGIIVVAEGALPREGTMELREGHIDQFGHKTFTGIGQQIADEIHVRLGHDVRTTVLGHIQRGGTPTAFDRVLATRYGVRAARACHEGSFDKVVALKGESIEMITFEEAVGTLKEVPFERWVTAQAMFG
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_BACFR
Sequence: MIVVPVKEGENIEKALKKFKRKFEKTGIVKELRSRQQFDKPSVTKRLKKERAVYVQKLQQVED
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ACYP_LACGA
Sequence: MKTVTMKVTGLVQGVGFRWTTQMIAQDLGITGTVKNNPDGSVSIVAQGEELPLEHFIKKIKASPSVAGHVDHVDLNTVSDAEKFTRFSVVY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: MST1_ORYSJ
Sequence: MAGGVIVANDGDGSAVDHGGRLTFSVVITCLVAASGGLIFGYDVGISGGVSTMEPFLRRFFPGVVRRMAEARPGNEYCVYDSQALTAFTSSLYVAGLVASLVASRVTRAMGRQAVMVMGGALFFAGGAVTGFAVNIAMLIVGRMLLGFGVGFTNQAAPLFLAEMAPTRWRGSLTAGFQFFLAVGVVIATVTNYFASRVPWGWRLSLGLAGAPAVVIFLGALFLTDTPSSLVMRGDTARARAALLRVRGAGADVEAELKGIVRAVEVARQGEDGAFRRMAARREYRPYLVFAVAMPMFFQLTGVIVISFFSPLVFRTVGFGSNAALMGNVILGAVNLVCLMLSTLVIDRYGRKVLFMVGGAIMIIAQVGVAWIMGAQVGKNGSEAMARPYAVAVVAFTCLHTAGFGWSWGPLGWVIPGEIFPVDIRSAGQAMNVSIGLGLTFVQTQSFLAMLCRFRYGTFAYYAAWVAVMTVFIAVFLPETKGVPLESMATVWARHWYWKRFAREQPKTSADEPTGTY
What is the function of this protein?
Mediates active uptake of hexoses by sugar:proton symport.
What are the official names of this protein?
Sugar transport protein MST1, Monosaccharide transporter 1, OsMST1, Sugar:proton symporter MST1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MAGBI_MACFA
Sequence: MPRGQKSKLRAREKRHQARCENQDLGATQAPVAEGESSSSANLLFGDRPQNLPAAETLSIPEALQGAPSTTNTIAPVSCTSSNEGASNQDEKSLGSSREAEGWQEDPLSKKVVSLVHFLLQKYEKKEPITKGDMIKFVIRKDKGHFNEILKRASEHIELAFGVDLKEVDPIRHYYAFFSKLDLTYDETTSDEEKIPKTGLLMIALGVIFMNGNRAPEEAVWEIMNVMGVYADRKHFLYGDPRKVMTKDLVQLKYLEYQQVPDSDPPRYEFLWGPRAHAETSKMKVLEFVAKMHDTVPSAFPSCYEEALRDEEQRAQARVAARAHTAAMANARSRTTSSSFSHAK
What is the function of this protein?
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases.  Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex (By similarity).
What are the official names of this protein?
Melanoma-associated antigen B18, MAGE-B18 antigen.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_CAMJ8
Sequence: MAHKKGQGSTQNNRDSIGRRLGVKKFGGEFVRAGNIIIRQRGTATHAGNNVGMGKDHTIFALIDGFVKFERKDKDRKKVSVYPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: NHAP2_SALNS
Sequence: MDAATIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGIGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFHLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIEMIQKHETGLDWMFAVHIIQQFGLGIVFGLGGGYLLQQMINRISLPSGLYPMLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVTPSDLWPIAVPALILSIWMIFFARPLSVFTGLLPFRGFNLRERIFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKRAKVVVPPVGWPVSRVGLDIHPDNPWEQFIYQLSADKWCVGAALRDLHMPNETRIAALFRNNELFHPTGSTRLQEGDVLCVIGRERDLPALGKLFSQSPPVSLDQRFFGDFILEANAKFADVALIYGLEEGTEYRDKQQTLGEIIQQLLGAAPVVGDQVEFGGMIWTVAEKEDNVVRKIGVRVAEDEAE
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRF_MYCLE
Sequence: MIDEALFDAEEKMEKAVSVAREDLSMIRTGRANPGMFSRLVIDYYGSATPITQLASINVPEARLVVIKPYDAIQLHAIETAIRNSDLGVNPSNDGTLIRVAVPQLTEERRRELVKQAKCKGEDAKVSVRNIRRKVMEELHRIRKDGEAGEDEVSRAEKDLDKTTHQYVIQIDELVKHKEGELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF5AL_HUMAN
Sequence: MADDLDFETGDAGASATFPMQCSALRKNGFVVLKGWPCKIVEMSASKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDFQLIGIQDGYLSLLQDSGEVPEDLRLPEGDLGKEIEQKYDCGEEILITVLSAMTEEAAVAIKAMAK
What is the function of this protein?
mRNA-binding protein involved in translation elongation.  Has an important function at the level of mRNA turnover, probably acting downstream of decapping.  Critical for the efficient synthesis of peptide bonds between consecutive proline residues.  Can resolve ribosomal stalling caused by consecutive prolines during translation (By similarity).  Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity.  Functions as a regulator of apoptosis.  Mediates effects of polyamines on neuronal process extension and survival.  May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 5A-1-like, eIF-5A-1-like, eIF-5A1-like, Eukaryotic initiation factor 5A isoform 1-like.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Note=Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions.
Protein: HTPX_SERP5
Sequence: MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNETENWLLETVRRQSQQAGIAMPQVAIYHAPDINAFATGARRNASLVAVSTGLLQSMSRDEAEAVIAHEISHVANGDMVTMTLIQGIVNTFVIFISRLIAQAAAGFLGNRDGEGEGNGNPMIYFGVSMVLELVFGILASIITMWFSRHREFYADAGSAKLVGREKMIAALQRLKTSYEPQEAGNMMAFCINGKSKSFSELFMSHPPLDKRIEALRSGQYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHI3_ORYSJ
Sequence: MRALALAVVAMAVVAVRGEQCGSQAGGALCPNCLCCSQYGWCGSTSDYCGAGCQSQCSGGCGGGPTPPSSGGGSGVASIISPSLFDQMLLHRNDQACAAKGFYTYDAFVAAANAYPDFATTGDADTCKREVAAFLAQTSHETTGGWPTAPDGPYSWGYCFKEENNGNAPTYCEPKPEWPCAAGKKYYGRGPIQITYNYNYGPAGQAIGSDLLNNPDLVASDATVSFKTAFWFWMTPQSPKPSCHAVITGQWTPSADDQAAGRVPGYGEITNIINGGVECGHGADDKVADRIGFYKRYCDMLGVSYGDNLDCYNQRPYPPS
What is the function of this protein?
Hydrolyzes chitin and plays a role in defense against fungal pathogens containing chitin.  Inhibits the growth of T. reesei fungus on plate assay.
What are the official names of this protein?
Chitinase 3, Basic endochitinase 1, Class I chitinase c, OsChia1c, Pathogenesis related (PR)-3 chitinase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: OPGD_XYLFM
Sequence: MLMYRRDFLKSVTAAWVAFGLPNPLGGAFATNRVIALRRLGQSQRFDYELLKERARALAAAPYHSRKRVLPTPLERLSWDQYQSIRYRQDHALWADSDAHFQVKFFHLGLYFHSPVRMYEVVDGMAQELAYDPAAFDYGSSGLNGKGLPKDLGFAGFRLNTRKDTDRDFAAFLGASYFRAVGQEGQYGQSARGLAVNTGSSGPEEFPDFIAYYLEQPTSDADTVVMYGLLDSPSIAGAYRFSITHADVLRMDIDSALYPRETIERLGIAPCTSMYQVGENDRRMGWDWRPEIHDTDGLFLWTGNGEWIWRPLCNPLHLRFNMFLDNNPRGFGLLQRDRDFDHYQDDGVFYEKRPCLWVEPKHGWGEGSVQLVEIPTFDETFDNIVAFWNPRNKPHPGQELLFGYRLYWGALPPVSSSLAYCVATRTGLGGVVGQKRKYFSWRFAVDFVGGKLAALARVHDVSVEPVLHMTRGRPEIVSARPLHEIRGYRVMFDVVPLEDSAQQIDIRLYLRDTNGEPLTETWLYQWMPPILEERKIY
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VP27_HIS1I
Sequence: MTEKTTKSKNSIATKNIVRVSLICFLLVFSVTVPFVFSPVSNASGQTTTLVDGFEDGTLSPWQTFQSFSVNTNNPYKGDYSAVANSDDNTIFVTTNNDQYTAATVAVNIKDSNNNARILFQDRPDSNNADLLANIYIESGNVGFYGGNGQDTGIDISYSEWVVFEIKNIDYSNQKYDIEVYDKSGNSLGSFSGADFYDSVSSMNGVDIYKVDSGSRVDHFTTGEFVSKSTVSGNVTDLEGNPMANATVTADSVSTTTDDNGSYSIKLADGTYDITANKKNYKPQTKQIEVNGSAKTVDFSLGKIEKQLSIEGPNFVRPNQTIPYKVEYTNETGTYDVSNYSNITSANTTLLSIDETNKTLLAGGQNATVKVTAKYNTTEVTTNVTKQYYVSYLKLENIDTVPPAKWMQAFLGFDDGYAENKNMKGIGSDIQWLLFTVIIMSTIAKLFDNPWAGIGSGVITGVLLWVLEYIGLGLLLSMVFFGIFIGLILVRVRRDGGNEVTINES
What are the official names of this protein?
Structural protein 27.
What are the subcellular locations of this protein?
Virion.
Protein: NADE_ESCF3
Sequence: MTLQQQIIKALGAKPQINAEEEIRRSIDFLKSYLKTYPFLKSLVLGISGGQDSTLAGKLCQMAINELRAETGNETLQFIAVRLPYGIQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDRPSLPDEAALGVSYDNIDDYLEGKTVPEQVAKTIENWYLKTEHKRRPPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: HDRE_METAC
Sequence: MSSEMAYFSGLTDALRLTFVQIMILSTIAIVVFLYGMILNFQKWGAGVTGYALEPQAGSKGSAIRFLKTWWGQVVEESHHGHGKPILEVLILDILFQRRILKRSPLRWFMHFTIFAGWMTLFALSGLMFAVEMTEKFGIELPFTPAEFREFLSIPNYIFGYILLIGVLIALVRRIVVSDVREASIMYDWILIGGVFLVTISGFVADGIRTGIIWGFGLDPTTAPPAALFHSVISLFFCIAYIPYSKYIHVIATPLAILANKGGE
What is the function of this protein?
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).  HdrE may be responsible for anchoring the complex to the membrane.
What are the official names of this protein?
Dihydromethanophenazine:CoB--CoM heterodisulfide reductase subunit E, CoB--CoM heterodisulfide reductase subunit E, Coenzyme B:coenzyme M:methanophenazine oxidoreductase subunit E.
What is the protein family that this protein belongs to?
Belongs to the HdrE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMH_BACC2
Sequence: MNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEMLIVKEKEGIRILDKISDDTHVIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLGLSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRINRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH_STRS2
Sequence: MTATKQHKKVILVGDGAVGSAYAYALVNQGIGQELGIIDINKDRTQGDAEDLSHALAFTFPKKIYSAEYSDAHDADLVVLTAGLPQKPGETRLELVEKNLRINQQIVTEIVNSGFNGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAEKIGIDARSVHAYIMGEHGDSEFAVWSHANVAGVKLYDWLQDNRDIDEQGLVDLFVSVRDAAYSIINKKGATYYGIGVALARITKAIFDDENAVLPLSVYQAGQYEGVEDVFIGQPAIIGAHGIVRPVNIPLSDAELQKMQASAKQLKDIIDDAFANPEIAAGVKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_BUCCC
Sequence: MAKYLGPKLKLCRRENSDLFLKSGVRTIESKCNIDQAPGQHGSRKLRLSEYAKQLREKQKLRRLYGILEKQFHNYYKKASKLKGNTGQNLLFLLESRLDNIVYRLGFGTTRLEARQLINHKSICVNNKIVSFPSFQVSIDDKISVVKKSKNQLRIKASLEIMKQKEKPSWLSIDYPNMEGVFLRSIERDDLSSDINEHLIIELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.