PharMolix/UniProtQA huggingface dataset:
Protein: MDH_SULTO
Sequence: MTKIAFIGVGKIGQTIAFNTIMDGYADEVMIYDIIPELPEKFEHELRHALASKRLKVELLSTNNLDDVAGADIVVITAGKPRKPGMSRRDLFVDNAKIMMDLANKLPKKNHGAVYIMVSNPVDMMASVFARYSREFVISTGDQVETMRLRAYIAKKLKIPVYRVNGFVGGEHGEDAVVLWSTVTVNGKPFSEDLGVTKAEVEDYVKKIPGEIIRVMGGTTWGPGTIIAELIRAVALNENKVMSIATPRQFEDEIIHVSVPTVVGSSIGPSLENLLDEKDRWNLMASMKDFYNVYKENLKHLETSIQAQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: EFTU_DINSH
Sequence: MAKEKFERSKPHVNIGTIGHVDHGKTTLTAAITKQFGDFKAYDEIDGAPEEKARGITISTAHVEYETDARHYAHVDCPGHADYVKNMITGAAQMDGAILVVNAADGPMPQTREHILLGRQVGIPYMVVFMNKVDQVDDEELLELVEMEIRELLSSYEYPGDDIPIIAGSALAALEGRDPEIGEQKIAELMKAVDDYIPTPARAVDQPFLMPIEDVFSISGRGTVVTGRVERGVINVGDEIEIVGIRDTKKTTCTGVEMFRKLLDRGEAGDNIGALLRGVDREGVERGQVLCKPGSVTPHTKFEAEAYILTKEEGGRHTPFFANYRPQFYFRTTDVTGTVTLPEGTEMVMPGDNLKFGVELIAPIAMEDGLRFAIREGGRTVGAGVVSKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATL1_CHICK
Sequence: APRSVDWREKGYVTPVKDQGQCGSCWAFSTTGALEGQHFRTKGKLVSLSEQNLVDCSRPEGNQGCNGGLMDQAFQYVQDNGGIDSEESYPYTAKDDEDCRYKAEYNAANDTGFVDIPQGHERALMKAVASVGPVSVAIDAGHSSFQFYQSGIYYEPDCSSEDLDHGVLVVGYGFEGGKKYWIVKNSWGEKWGDKGYIYMAKDRKNHCGIATAASYPLV
What is the function of this protein?
Important for the overall degradation of proteins in lysosomes.
What are the official names of this protein?
Procathepsin L, Cathepsin L1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Apical cell membrane; Peripheral membrane protein; Extracellular side. Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Secreted, extracellular space. Secreted.
Protein: IF1_PARD8
Sequence: MAKQSAIEKDGVIVEALSNAMFRVELENGHEITAHISGKMRMHYIKILPGDKVRVEMSPYDLSKGRIAFRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_YERPN
Sequence: MFIGDASILKPIQWCATEHPELPADIADWLMELGSMTRRFEQHCQRVHVEPQRECFITRDALGEEAEHLPVSQRYWLREIVLFGDNVPWLLGRTVIPEETLSGPDRALVDLGTLPLGRYLFSGDALTRDYIHVGRQDNLWARRSLLRLSGNPLLLTEVFLPASPLYTHCDSIPK
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_BURMA
Sequence: MKLTPREKDKLLIFTAALLAERRRARGLKLNYPETVAFITAALMEAARDGRTVAEVMHYGTTLLTRDDVMEGVPEMIPDIQVEATFPDGTKLVTVHHPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2979_STAA8
Sequence: MPKNKILIYLLSTTLVLPTLVSPTAYADTPQKDTTAKTTSHDSKKSNDDETSKDTTSKDIDKADKNNTSNQDNNDKKFKTIDDSTSDSNNIIDFIYKNLPQTNINQLLTKNKYDDNYSLTTLIQNLFNLNSDISDYEQPRNGEKSTNDSNKNSDNSIKNDTDTQSSKQDKADNQKAPKSNNTKPSTSNKQPNSPKPTQPNQSNSQPASDDKANQKSSSKDNQSMSDSALDSILDQYSEDAKKTQKDYASQSKKDKNEKSNTKNPQLPTQDELKHKSKPAQSFNNDVNQKDTRATSLFETDPSISNNDDSGQFNVVDSKDTRQFVKSIAKDAHRIGQDNDIYASVMIAQAILESDSGRSALAKSPNHNLFGIKGAFEGNSVPFNTLEADGNQLYSINAGFRKYPSTKESLKDYSDLIKNGIDGNRTIYKPTWKSEADSYKDATSHLSKTYATDPNYAKKLNSIIKHYQLTQFDDERMPDLDKYERSIKDYDDSSDEFKPFREVSDSMPYPHGQCTWYVYNRMKQFGTSISGDLGDAHNWNNRAQYRDYQVSHTPKRHAAVVFEAGQFGADQHYGHVAFVEKVNSDGSIVISESNVKGLGIISHRTINAAAAEELSYITGK
What are the official names of this protein?
N-acetylmuramoyl-L-alanine amidase domain-containing protein SAOUHSC_02979.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SCYD_MAGO7
Sequence: MGSQVQKSDEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK
What is the function of this protein?
Scytalone dehydratase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene melanin, a bluish-green pigment and a structural component of the conidial wall (PubMed:9571787).  Within the pathway, catalyzes the dehydration of scytalone as well as of vermelone (PubMed:9571787, PubMed:9466791, PubMed:9466792, PubMed:9539706, PubMed:10320327, PubMed:10386945, PubMed:10386946, PubMed:10694394, PubMed:10913266, PubMed:10636235, PubMed:11790103, PubMed:12413868, PubMed:15056895).  Is also able to dehydrate the alternate substrate 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one (DDBO) to 5-hydroxy-4H-1-benzopyran-4-one (HBO) (PubMed:9466791, PubMed:9466792, PubMed:10320327, PubMed:10386945, PubMed:11790103).
What are the official names of this protein?
Scytalone dehydratase, SD, SDH.
What is the protein family that this protein belongs to?
Belongs to the scytalone dehydratase family.
What are the subcellular locations of this protein?
Endosome.
Protein: HLDE_ALIFM
Sequence: MKPTLPNYDQSSVLIVGDVMLDRYWGGPTSRISPEAPVPVVKVEKIEERPGGAANVAMNIAALGGDAHLVGLVGEDEPAQALTTTLESLKVHCDFVALPEFPTITKLRVMSRGQQLIRLDFEDSFHDVAAEPIISRMQQALSSVKAVVLSDYAKGALEHVQSMIQEARKVNVPVFIDPKGADFERYRGATLLTPNMLEFETVVGKVKDEDDLVAKGQQIIEEFDFEALLVTRSEHGMTLLRRNMEPLHLPTQAREVFDVTGAGDTVISVLAASVSTGKPLDEACALANAAAGVVVGKLGTSTLSTIELAEAIHGSQDSGFGIIGEEQLISAVKQARARGEKVVMTNGCFDILHAGHVSYLNHAAELGDRLIVAVNTNESVQRLKGPGRPINPTDRRMAVLAGLGAVDWVVPFSEDTPQRLISQVLPSLLVKGGDYAIEDIAGGAEVIAAGGEVKVLNFEDGCSTTGIIEAIKGGRG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: DAPEL_LISW6
Sequence: MLNEFIAIRRDLHQIPETGYKELKTQAYLLAYISKLPNKHLEVKKWRTGILVLVKGTKPEKTIGYRTDIDALPITEETGLPFESNHVGNMHACGHDLHMSIALGVLTHFASKPAKDNLLFVFQPAEEGPGGAKPIMESEEFAAWRPDTIYGLHIAPEYKVGEIAIKPGLLFANTSELFISFKGKGGHAAYPHLANDMVVAASAFVGQMQTIISRNIDPMDSAVITIGRIHGGEIQNVIAETAFLDGTIRTLSPETMEIVWTRLKQLAKGWEEAYQCEVEFHPGSDYYQVDNEPLETEEFIRFLKEHYPESYVPARSAMTGEDFGYFLSEIKGFMFWLGVDSEYSLHHAKLNPKEEAIPFAIDVLINFLESK
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: THIC_AGRVS
Sequence: MNIAPQFPTPEVTTGTLPASAKVHIAGEIHPQIRVPMRQITLHPTSGEPPVNVYDSSGPYTDPNATIAIDAGLPRIRAEWVVARGDVEPYAGRHVKPEDNGFASGEKLTPEFPVRNAPLRAKPGQAVTQLAYARAGIVTPEMEFIAIRENIGRKAAKDALIRDGESFGASIPDYVTPEFVRQEVAMGRAIIPANINHPEAEPMIIGRNFLVKINANIGNSAVTSSMAEEVEKMVWAIRWGADTVMDLSTGRNIHNIRDWIIRNSPVPIGTVPLYQALEKVHGIAENLTWDVFRDTLIEQAEQGVDYFTIHAGVRLSYIHLTVNRVTGIVSRGGSIMAKWCLHHHKESFLYEHFDEICDICRAYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTKIAWAKDCQVMIEGPGHVPMHKIKENMDKQLKTCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGTAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLAKGHPAAQVRDDALSRARFEFRWEDQFNLSLDPDTARSFHDETLPKEAHKVAHFCSMCGPKFCSMRISHDIRAEAQKEGLEAMAAKYRDGGDLYMPVSDEEKPSVGE
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: FDHE_ECOL5
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTTRIKEASAQGKPPLDIHVLPRDKHWQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAVADDLASLVLDARMEQEGYARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBP1_KLULA
Sequence: MSSNQIYSAKYSGVDVYEFIHPTGSIMKRKADNWVNATHILKAAKFPKAKRTRILEKEVITDTHEKVQGGFGKYQGTWIPLELASKLAEKFEVLDELKPLFDFTQQEGSASPPQAPKHHHASRSDSTRKKATKSASVPSGKVSEKASSQQQQPVSQQQQQQPGSAPKRRGRPPRNKATVTLQRSQSEMVFPKPSIPSSSIQSTKLPSLQPQFGRSATSLSPIMDVKSPLDQASPQFKELDIEDGLSSDVEPNSIMGTKHEDNTHLMNTKDEPVSSSSSLPSSPSEFSQSVAFGSRSNMQTPLQLNGTTSMNMILPKFSSSQNGPSDSNQRANEYLSKLVNYFISNDTQNESEIPMELLNPPLHCSPFIDTWIDPEHHTAFHWACAMGTLPIVEALLKAGSSIRSLNNVGETPLIRSSIFHNCYTKRTYPQIFEILKDTVFDLDAKSRNVIHRIVSRKSHTPSAVYYLDVVLSKIKDFTPQYRIDVLINQQDNDGNSPLHYAATNKDDQFYQLLLQNGALTTVQNNSGMTPNGIISGRYSMDEITKGQRLDDPYEFNKMYPSQAATRTNRIIPEVINMMKEMANSYQNAYQKRQNEVLQMERTVKSMKKTITSVEMKLLEALNLKETDNVDIVLNDRKEKIDELQRRIATDKRVLINRLEEGQVKLIRKFVDEETKNVEGKTTDGEESEDIEALLKELVLIQLKRKRKLNQIIDVITDNSKVYKYRKMISQGTDIDVSDVDECLDVIYQTLSKEG
What is the function of this protein?
Binds to MCB elements (Mlu I cell cycle box) found in the promoter of most DNA synthesis genes.  Transcriptional activation by MBF has an important role in the transition from G1 to S phase.  It may have a dual role in that it behaves as an activator of transcription at the G1-S boundary and as a repressor during other stages of the cell cycle.
What are the official names of this protein?
Transcription factor MBP1, MBF subunit P120.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTS_HALOH
Sequence: MSKLTPMMQQYQSIKNKYKDAILFFRLGDFYEMFNDDAKIAARELDLALTARNKGGGEKAPMAGVPCHSAESYIAKLLEKGYKVAICEQIEDPSEAKGLVSREVVRIITPGTIIENEMLKDKENNYLASAICYKDHLGFSYVDISTGEFYVTQFSQKFSDKVWDELDRIQPREVIICKELEETENFADKKKQMNFVYNYSRIEKVKAAYNFLLEHFKTNSLSGFGCEDKPAAILAAGEIINFLKDTQKRTLEHINRITTYNLTDYMVLDSATRYNLELTSTIRGNKHKGSLLNVLDQTITSMGGRLIKKWINQPLIDRNKIETRLDAVEELVNNYLLLQEIREHLKGIYDLERILGKVSYGSANARDLAALKYSILKLPQIKKDLEQLNTKLFKNMHETFDPLIDLAGLLDRSIVDEPPVSVREGGLIKDGYSSELDELRKARTEGKDWIANLQKTERERTGISSLKVGFNKVFGYYIEITKANLDRVPDNYTRKQTLSNSERFITPELKEKEALVLGAEEKINDLEYKLFVKIRDIVRDNIKRIKKTAAIISKLDVLTSLAQNALERDYNRPRINNDGVIEIIKGRHPVVEDMGKGAFVPNDTYLDLEEERFIIITGPNMSGKSTYMRQVALIVLMAQMGSFVPADKATIGIVDRIFTRVGASDDLTTGQSTFMVEMNEVANIVNNATRNSLIILDEVGRGTSTYDGLSIAWAVSEYINNPDRIGARTLFATHYHELTQLENRPGIKNYNVLVEEDEDGVHFLHKIIPGKASESYGIEVAQLAGLPMEIIIRAQEILAELEKKGKESTKTGKGENKNISHKTESDLINNIHESDKEYLTKRNTNDKVQQLPLFKSEYRVIEKIKNKDIVNMTPMEAINFLFEIQKELKEKGENYA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: ISPH_FRATW
Sequence: MKILLANPRGFCAGVSRAVETVEKVLEVEKSPVYVRHEVVHNKVVVDSLKKKGVVFVKEVDEVPDDAVCIFSAHGVSLKVEEAAAKKNLVLYDATCPLVTKVHRGVRLASNNDAECILIGHKGHPEVQGTMGQYRSKKGAIYLIESEEDLNKLTIKDPDNLYYATQTTLSVDETQGIIQALKDKYPNIKGPKKEDICYATQNRQTAIKAMLKHIDVLVVVGSQNSSNSNRLKELATLEGIDAYLVDNPKDVDKLWFDNKKVCGVSAGASAPEYLVQQIISQISKVCSTEVEEFEGIKEEVYFPLPRLLKQKIGTGKVE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: VF79_ASFWA
Sequence: MNKTIEYQKEFLKENNQLLSIPVKKNILKEILQNDEQDTIITNCITKEVSINLDLIKNPKVLYSIYIMVVEYLKSMNIA
What are the official names of this protein?
Uncharacterized protein D79L, pD79L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus D79L family.
Protein: SYDND_BEII9
Sequence: MHRYRTHTCGDLREAQADETTRLSGWCHRIRDHGGVLFIDLRDHYGITQCVVDPDSKAFPLAEKLRSEWVVRIDGLVRKRPSGTENPEMPTGFIEIYVTEIEVLGAAAELPMPVFGDIDYPEDIRLKYRFLDLRREKLHKNIMLRGQVIDSLRRRMKEQGFFEFQTPILTASSPEGARDFLVPSRIHAGKFYALPQAPQQYKQLLMMAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDVEMSFITQEDVFAAMEPVIRGAFEEFGNGQPVTQTFPRIPYAEAMLKYGSDKPDLRNPLVIADVTDLFARDDVSFNAFKNVIKKGGVVRAIPATGAASQPRSFFDKLNDWAKSEGAAGLGYVIFEGSDEAPVGKGPIAKFLPAEVQAAIVTRADLKAGDAVFFACDIEEKAAKLAGAARLRIGHELGLSKTGVFELCWIVDFPMYEWNEDDKTVDFSHNPFSMPQGGLEALQTQDPLTIKAFQYDIACNGYEIASGGIRNHRPEAMVKAFEIAGYGEETVVERFGGMYRAFQYGAPPHGGMAAGVDRIIMLLAGVQNLREISLFPMNQKAEDLLMGAPSEATTKQLRELHIRLNLPEPK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARD_ECOLX
Sequence: MSRLTIDMTDQQHQSLKALAALQGKTIKQYALERLFPGDADADQAWQELKTMLGNRINDGLAGKVSTKSVGEILDEELSGDRA
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system involved in plasmid partition.  Inhibits the anti-DNA gyrase activity of toxin ParE; reverses and restores gyrase catalytic activity in vitro.  The parDE operon alone is capable of stabilizing an RK2-derived minireplicon under defined growth conditions in several different Gram-negative bacteria.  It does so by the post-segregational killing (PSK) of plasmid-free cells, also referred to as a plasmid addiction system.  Binds its own promoter, autorepressing it; gentically only ParD is required for full autorepression.
What are the official names of this protein?
Antitoxin ParD.
Protein: GPMB_CITK8
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVGERARTLGITHIVSSDLGRTRRTAEIIAQACGCDITFDARLRELDMGVLEKRHIDTLTEEEENWRRQLVNGTVDGRIPDGESMQELSDRVNAALASCLELPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLAPGWVVETAGDVSHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: GCNT7_MOUSE
Sequence: MSQLRTTKAGLVACGMICAFIFLYLRNPGPEEAEAEAEAEPTNPAVVECGFYPDELCSALFDGKKAAPQIAQFCKPPQNSEVPARLRTPGNCSRLARGLHFITRPLSAEEGNFSLAYVIHAPRELVMFVRLLRAIYAPQNVYCIHSDENAPKKFKSAMQTFVDCFGNIFLSSKTQKVAHDNLRRLQAEIDCMRDLVHSPFQWHYVMNLCGQEFPIKTNKEIIYDIRTRWKGKNITPGVTPPANSKPKTGQGPPKPSPDENSYTAPNTIFKQSPPHNLTISSGSAHYALTRKFVEFVLTDPRAKDMLQWSKDIQSPEKHYWVTLNRLKDAPGATPDAGWEGHIRATKWRTEAGDGRKGCTDHDAQDTCVYGLGDLPGLIRLPAFFATLEPSSDPLVGVCLERRHRLRALQQAEVPPEPHWQFPQQSHFNSQPHH
What is the function of this protein?
Glycosyltransferase.
What are the official names of this protein?
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: VP7_ROTBK
Sequence: MYGIEYTTFLIYLISIILFNYILKSITRMMDYIIYKFLLIVTITSIVVNAQNYGVNLPITGSMDTSYVNATKGKPFLTSTLCLYYPTEARTEINDNEWTNTLSQLFLTKGWPTGSVYFKEYDDIATFSVDPQLYCDYNIVLMRYNSNLELDMSELANLILNEWLCNPMDITLYYYQQTDEANKWIAMGQSCTIKVCPLNTQTLGIGCQTTNTRTFEEVATAEKLVITDVVDGVNHKLDVTTATCTIRNCKKLGPRENVAVIQVGGADILDITSDPTTNPQTERIMRINWKKWWQVFYTIVDYVNQIVQAMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: PTU3C_STAA2
Sequence: MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVMEAAGQVVFDNLPLLFAVGTALGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAWCYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVLLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGLHHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLKDGVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKVVGGLMLSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVGIVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIKALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGVGQIIPLSEVPDQVFAGKMMGDGIGFIPEKGEIVAPFDGTVKTIFPTKHAIGLESESGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQGQPLMKVNLAYLKAHAPSIVTPMIITNLENKELVIEDVQDADPGKLIMTVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in alpha- and beta-glucoside transport (By similarity).
What are the official names of this protein?
PTS system glucoside-specific EIICBA component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTL_BRUO2
Sequence: MTIRHLSETIINQIAAGEVIERPASVIKELVENAIDAGATRIEVVTAGGGKTLLRVTDNGSGIPADELALAVSRHCTSKLTDDVHDIRALGFRGEALPSIGSVSKLTLKSRPQDADSGFEVCVTGGHLDGPRPTALNRGTIVEVRDLFYATPARLKFMKTDRAEATAITDVVKRIGIAFPHIRFSLAGTDRTPFEMPATGTGAEATLERIGQVLGREFGENALAIDAERDGVRLAGFVGIPSFNRGNALHQFAYVNGRPVRDKQIFGALRGAYSDVIARDRHPVAVLFLTLDPALVDVNVHPAKADVRFRDPGLVRGLIVGAIKQALAQSGIRPATSGAEAMLQAFRAEGFGAQQSAPRPANSYSPASWRTAPPAPRSEWSPQTAHPAHRPLDLQAAPALRENGQAVLGDVAVPAADARASVAEAPVELMQKPLGAARAQIHENYIVAQTEDSLVIVDQHAAHERLVYEALKNALHARPIAGQMLLIPEIVDLPEEDAQRLAGHAETLARFGLGVEQFGPGAIAVRETPAMLGEMNVQQLIRDLADEIAEHDTADGLKAMLHHVAATMACHGSVRSGRRLKPEEMNALLRDMEATPGSGTCNHGRPTYIELKLTDIERLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MNMA_MYCBT
Sequence: MKVLAAMSGGVDSSVAAARMVDAGHEVVGVHMALSTAPGTLRTGSRGCCSKEDAADARRVADVLGIPFYVWDFAEKFKEDVINDFVSSYARGETPNPCVRCNQQIKFAALSARAVALGFDTVATGHYARLSGGRLRRAVDRDKDQSYVLAVLTAQQLRHAAFPIGDTPKRQIRAEAARRGLAVANKPDSHDICFIPSGNTKAFLGERIGVRRGVVVDADGVVLASHDGVHGFTIGQRRGLGIAGPGPNGRPRYVTAIDADTATVHVGDVTDLDVQTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGASGLSTGGNPGA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_RHOPA
Sequence: MKSAVLVFPGINRERDMARALKLVSGNDAAMVWHAETELPKGTDLVVVPGGFSYGDYLRCGAIAARAPVMDAVRKFAADGGLVLGVCNGFQILCESGLLPGVLMRNARLKFICRDVHLRVERNDTPFTQGYKAGQVIKVPVAHGEGNYEADEDTVKRLEGDGRVLYRYCSPEGEVGESHNINGAAASIAGIVSERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLAQHLAKAA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_NATTJ
Sequence: MMNTYDNQHREQQKLSENILKTKPLIAIVGPTAVGKTDISIKVAERLPVSTGIISADSMQVYKKMDIGTAKPSQEIRTKIPHYLVDNVEPDEEFSVGRYQKHAKSILNQLYQNKELPLLVGGTGLYVDALIYDFSMNELPKSTKYRQELQQKAEQDGLEQLYRKLEKVDPDAADRIHPNDQRRIIRALEVYYYTGEPISQRQKRRYDSPYNLLIFGITMDRNKLYNKIETRVDQMIDQGLVEEVKYLLENGYHLQLTSMQGLGYKEIAGYLMGDYDLETAVQKLKKNTKRFAKRQLSWFRRDPNIKWLDITETDKSEICDKIIDMILKEYLE
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.