PharMolix/UniProtQA huggingface dataset:
Protein: SUFE_YERE8
Sequence: MAGLPDKDKLIRNFSRCLNWEEKYLYVIELGAQLPPLTEQQRQPDNLISGCQSQVWIAMSTSTEGQVVFAGDSDAAIVKGLVVVVFILYQGLTPQQIIDLDVRPFFADLALSQHLTPSRSQGLEAMIRAIRAKAAVLKAG
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_SCHNE
Sequence: RFKKIRRLGALPGLTSKRPRSGSDLKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQILLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKNKQRSKALIQNFIASSPQQEELPNHLTIDPFQYKGLVNQIIDSKWIGLKIN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PRS27_HUMAN
Sequence: MRRPAAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQFQPARLGGQK
What are the official names of this protein?
Serine protease 27, Marapsin, Pancreasin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHHA_HOMAM
Sequence: MMACRTLCLVVVMVASLGTSGVGGRSVEGASRMEKLLSSSNSPSSTPLGFLSQDHSVNKRQVFDQACKGVYDRNLFKKLDRVCEDCYNLYRKPFVATTCRENCYSNWVFRQCLDDLLLSDVIDEYVSNVQMVGK
What is the function of this protein?
MIH may inhibit Y-organs where molting hormone (ecdysteroid) is secreted and a molting cycle is initiated when MIH secretion diminishes or stops.
What are the official names of this protein?
Crustacean hyperglycemic hormones isoform A.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMA_SHEPW
Sequence: MNLAAMDPLTYDVQLEAKRVKLKQLFTDFDTPELESFSSETAHYRMRAEFRMWHEGEDLYYYMFDKELNSKVRCDQFLPASELINKMMPVLVELLKPNTILRHRLFQIDFLSTLSGEILVSLLYHKQLDAEWEEQAKILKQTLSSQFNVNLIGRARKQKLIFDKDFVVESLNVAGKQLQYHQIENSFTQPNGKVSVKMLEWAIDVTKNSTGDLLELYCGNGNFSIALAQNFERVLATELAKPSVESAQYNIKMNHVDNLQIIRMSAEDFTDAMAKKRSYRRLEGIDLDSYNCNTIFVDPPRAGLDENTVKLVQGYERIVYISCNPNTLLDNLKELSKTHNITRFVLFDQFPYTDHMESGVFLEKK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: GAS2_MAGO7
Sequence: MKYTSAILISAFAATNVFAHGVVTEVQGANGVTLPGLTAIDGTPRDCPNPGCGSEADTAIIRDRELGTSRASALGRTQGGGPVDAAKMIELFMDGASVNKSDVVAARERHAANLARRATLLPRAGGGTSTPKGTEETGVKAATGIAATKGLPTTNDDGTINIVFHQVNQDGAGPLTADIDSTSGGQDVSAFQKAKITTNVPGLGIAGLSAAQTMDFPVAVQMPAGATCSGSVGGANNVCIARLRNAAVTGPFGGSVAFTQSPAARKRAIEYNLAKRRFARSLATDEEDDE
What is the function of this protein?
Appressoria-specific virulence factor required for appressorial penetration in host and lesion development.
What are the official names of this protein?
Appressoria-specific virulence factor GAS2.
What are the subcellular locations of this protein?
Cytoplasm. Note=Exclusively located in the cytoplasm of appressoria cells.
Protein: GANC_MACFA
Sequence: EEEVVISINSLGQLYFEHLQILHKQRAAKENEEEASVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDEDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEYTLSQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKKRFPNPERMQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRRPEQTMQKNAIHHGNWEHRELHNIYGFYHQMATAEGLIQRSGGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSYLKISIPMLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNAKRREPWLFGKEHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEGGCTVKIPVALDTIPVFQRGGSVVPIKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSVLINSSADQRGHYPSKCVVEQILVLGLRKEPSFVTTHSSDGKDQPVAFTYCAKTSSLSLEKLSLNIATDWEVRII
What is the function of this protein?
Has alpha-glucosidase activity.
What are the official names of this protein?
Neutral alpha-glucosidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
Protein: ENGB_PARXL
Sequence: MSFLLHQSRFFTTVNHLQDLPATSQPEICFAGRSNAGKSTAINILCNQKRLAFASKTPGRTQHINYFSVGNADEPTAHLVDLPGYGYAEVPGAAKAHWEALLSAYLQSRSQLRGMILMMDSRRPLTDLDRRMIEWFVPTGKPIHTLLTKCDKLTRQESVNALRATQKGLAEYRAAGYRGELTAQLFSALKRIGIDEAHALIESWLIPEAKGETDTPQ
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: GAL1_STRMU
Sequence: MKKQELNQAFTHVFGREADATFFSPGRINLIGEHTDYNGGRVFPAAITLGTYGAARKRDDKLLRFYSANFEELGIIEISLDHLIFNKKDSWTNYPKGVIKYLQEAGHSIDTGMDVYVFGNIPNGSGLSSSSSLELLIGIMAEELFDLKLDRLDLVKIGKRTENDFIGVNSGIMDQFAIGMGAEKKAIYLDTKTLEYDLVPLDLGDNVIVIMNTNKRRELADSKYNERRTECEKAVEELNVLLDIKSLGELDEETFDEYAYLIKDAKRIKRARHAVSENQRTLKAKKALAAGDLEKFGRLVNASHVSLEHDYEVTGIELDTLAHTAWEQEGVLGARMTGAGFGGCGIAIVAKDKVAALKENVGRIYTETVGYAPAFYIAEIAGGSRVLSRK
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBAZ_ECO8A
Sequence: MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCREHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFSLREALFSLAAIEEELVPAKACSGLRQVLEDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYHTACEGQ
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of KbaY.  When expressed alone, KbaZ does not show any aldolase activity.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. KbaZ subfamily.
Protein: LTOR1_XENLA
Sequence: MGCCYSGETDTGKGDQGEREHLLPQNQSLPNNKQNGSEQNPTNNPSARTDEQAMLSRILAKTAQNIIDVSAVESQGMEQHECMDRARQYSTRLAKLSSNLMDWKNVPPLPSLTSQPHQILASDPVPFTDIQQVSKIAAYAFSALSQIRVDAKEDLVVQFGIP
What is the function of this protein?
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids.  As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids.  May play a role in late endosomes/lysosomes biogenesis and regulate both the recycling of receptors through endosomes and the MAPK signaling pathway.  May be involved in cholesterol homeostasis.  May also play a role in RHOA activation (By similarity).  Involved in the control of embryonic stem cells differentiation; together with FLCN it is necessary to recruit and activate RRAGC/RagC and RRAGD/RagD at the lysosomes, and to induce exit of embryonic stem cells from pluripotency via non-canonical, mTOR-independent TFE3 inactivation (By similarity).
What are the official names of this protein?
Ragulator complex protein LAMTOR1, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR1 family.
What are the subcellular locations of this protein?
Late endosome membrane; Lipid- anchor; Cytoplasmic side. Lysosome membrane; Lipid-anchor; Cytoplasmic side. Cell membrane.
Protein: RL11_PROM0
Sequence: MAKKIVAVIKLALQAGKANPAPPVGPALGQHGVNIMAFCKEYNARTQDKAGFVIPVEISVFEDRSFTFITKTPPASVLITKAAGIEKGSGESAKGSVGNISKAQLEEIAKTKLPDLNCSSVESAMKVIEGTARNMGVSITD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: HST3_CANAL
Sequence: MISIDLLDNSGTSMPADTSIKLHEVIKFISKSKKMTVLTGAGISCNAGIPDFRSSDGLYNMVKAKHPKAVVRGQDLFDISLFRDEMSLSVFCTFMESLYKSSLNAKPTETHKFIKILKDKNKLLRCYTQNIDCIEQHINLKLGINLQEFDNNKFKQVWNQLDVVQLHGNLHKLSCTNCFSQFNWNEEFQTLLANGLNPECSKCMDKYQQRLYSGKRLTGQTIGLLRPDIVLYGEHHPQMEILTQGLNSDLKSRPDCLIIMGTSLKVAGVKSLVKSLSKIIHNKGGKVIYVNKTKLSASSWKNYIDYEVVSDCDEFVRMLKTEIPDLFLTQEQLDSEKLNQVAVKGSSLNKPIVKPEAKVKIEPGIKQEDAIQYSPEREVTIKQEVNIKQEPIVKREVESVSVKEEPIPTPPTTPHKPKQATKLKRKSPDEISANEVHSRVKRLRPRNDQLSSPASSINGSEEEEEEDEPVAKVLFENARKGITLDQH
What is the function of this protein?
NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability.
What are the official names of this protein?
NAD-dependent histone deacetylase HST3, Homologous to SIR2 protein 3, Regulatory protein SIR2 homolog 3.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ITA5_MOUSE
Sequence: MGSWTPRSPRSPLHAVLLRWGPRRLPPLLPLLLLLWPPPLQVGGFNLDAEAPAVLSGPPGSLFGFSVEFYRPGRDGVSVLVGAPKANTSQPGVLQGGAVYVCPWGTSPIQCTTIQFDSKGSRILESSLYSAKGEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKDPQNDPVGTCYLSTENFTRILEYAPCRSDFGSAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQISESYYPEYLINPVQGQLQTRQASSVYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTVLNGSDIHSLYNVSGEQMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQRPAGIDPTPTLTLTGQDEFSRFGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGVVFIFPGGPGGLSTKPSQVLQPLWAAGRTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKALVYRGRPIISASASLTIFPSMFNPEERSCSLEGNPVSCINLSFCLNASGKHVPNSIGFEVELQLDWQKQKGGVRRALFLTSKQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPKAPMDSHGLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQLDVYGEKKHVYLGDKNALNLTFHAQNLGEGGAYEAELRVTAPLEAEYSGLVRHPGNFSSLSCDYFAVNQSRQLVCDLGNPMKAGTSLWGGLRFTVPHLQDTKKTIQFDFQILSKNLNNSQSNVVSFPLSVEAQAQVSLNGVSKPEAVIFPVSDWNPQDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALEGQQLLYVTKVTGLSNCTSNYTPNSQGLELDPETSPHHLQKREAPGRSSTASGTQVLKCPEAKCFRLRCEFGPLHRQESRSLQLHFRVWAKTFLQREYQPFSLQCEAVYEALKMPYQILPRQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKLGFFKRSLPYGTAMEKAQLKPPATSDA
What is the function of this protein?
Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen.  It recognizes the sequence R-G-D in its ligands.  ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.  ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.  ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling.  ITGA5:ITGB3 is a receptor for soluble CD40LG and is required for CD40/CD40LG signaling (By similarity).
What are the official names of this protein?
Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Cell surface.
Protein: CH60_METHJ
Sequence: MSAKQLMFNENARHALLEGVNKVANTVKITLGPKGRNVVLDKAGGPVVTNDGVTIAKEIELKDKFENVGAKLIKEVASKTQDTTGDGTTTATVLAQAMITEGIKNITAGANPIEIKKGILKAVDAAVASIKAKSIEVKDKETINRIAIISANNDEEIGNLISEAMDRVGYNGVITVENSKTLETTLEHVEGMQFDRGYISPYMVTDQERRVVEFEEPYILITDRKISSLKTLIPVLEMIAQSGKPLLIIADDVDGEAQTALILNIIRGAIKVCAVKAPEFGDVRKEVLQDIAILTGGTVISEERNLAIEDVTLDMLGQARTVKVDQDKTTIVGGKGKKSDIDTRKKLIESQLNITEKKYDKTTLQNRLAKLSGGVAVIKAGAATETEVKEKKMRIDDALNATKAAVEEGYVAGGGVTLFRAIKALESMKADPEQMIGVNIVKRALEEPLRQIADNAGREGAEVIAMIKSNASETYGYNAKTDTYEDLLQAGVLDPTKVVRSGLQNAASIAGMLLSTEAVVVDFDEEKDKTSAAIII
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2235_MYCTO
Sequence: MPRLAFLLRPGWLALALVVVAFTYLCFTVLAPWQLGKNAKTSRENQQIRYSLDTPPVPLKTLLPQQDSSAPDAQWRRVTATGQYLPDVQVLARLRVVEGDQAFEVLAPFVVDGGPTVLVDRGYVRPQVGSHVPPIPRLPVQTVTITARLRDSEPSVAGKDPFVRDGFQQVYSINTGQVAALTGVQLAGSYLQLIEDQPGGLGVLGVPHLDPGPFLSYGIQWISFGILAPIGLGYFAYAEIRARRREKAGSPPPDKPMTVEQKLADRYGRRR
What are the official names of this protein?
Uncharacterized SURF1-like protein MT2294.
What is the protein family that this protein belongs to?
Belongs to the SURF1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MP_MSVTA
Sequence: MDPQNSFLLQPRVPTAAPTSGGVSWSRVGEVAILSFVGLICFYLLYLWVLRDLILVLKARQGRSTEELIFGIQAVDRSNPIPNTQAPPSQGNPGPFVPGTG
What is the function of this protein?
Involved in the viral transport within, and between cells.
What are the official names of this protein?
Movement protein, MP.
What is the protein family that this protein belongs to?
Belongs to the mastrevirus movement protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: SECY_BUCBP
Sequence: MIKKKLETKLKNFGNQFSELKQRMYFVIFSLIVFRMGSYIPIPGIDTVALASLLEHHRGTIIEMFNMFSGGALSRASIFALGIMPFISSSIIVQILTLIHPKFIEMKKDGEQGRHRINKYIRYITLILAALQSFGMSISLPNIPGLKDVIIDPSISFYGIAIISLITGTIFLMWLGELITEKGIGNGISIIIFSGIVSGLPSSFLNTVEKVRQGSLHVLLFCFIGIVIFLVTLLVVYIERSQRKITISYAKRNLGHRTYSMNSTHLPLKLNMSGVIPAIFASSIVLFPATIASWFGNRDHFKWLVDIVFYLQPTKPLYILTYITAIIFFCFFYTGLAFNPRETADNLKKSGAFILGIRPGEKTAQYINKIMLRLTFLGSMYMAFICLVPELMRFFMDVPFYFGGTSLLIIVVVIIDFISQVQTYIMSTQYESVLKKNKFRF
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PROA_HAEIN
Sequence: MLEQMGKQAKDAAFILAQLTTAEKNCALSIIAEQLEQQAPLILAENAKDIELAKQNGLSDALIDRLLLTQERLQGIANDVRHVISLADPVGKIIDGGTLDSGLKIERVRTPLGVIGTIYEARPNVTIDVASLCLKTGNAVILRGGKETQFSNKILIEVVQNALEQAGLPKFAVQAITDPNRELVMQLLKLDRYVDMIIPRGGSGLHELCKQHSTIPVIVGGVGVCHTFVEKSADQNKAIFVIDNAKTQRPSTCNTLETLLVQHSIAEEFLPKLVSHLSAKNVKYHAKSTALNILKQAGANVCEVTEKELRKEWGSLDLNVVVVEDIHAAIEHIRQYGTQHSESILTSSQSLARQFINQVDAAAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTSYKWVCEGEYTVRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBM_MYCTU
Sequence: MTVYFIGAGPGAADLITVRGQRLLQRCPVCLYAGSIMPDDLLAQCPPGATIVDTGPLTLEQIVRKLADADADGRDVARLHSGDPSLYSALAEQCRELDALGIGYEIVPGVPAFAAAAAALKRELTVPGVAQTVTLTRVATLSTPIPPGEDLAALARSRATLVLHLAAAQIDAIVPRLLDGGYRPETPVAVVAFASWPQQRTLRGTLADIAARMHDAKITRTAVIVVGDVLTAEGFTDSYLYSVARHGRYAQ
What is the function of this protein?
Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5.
What are the official names of this protein?
Precorrin-4 C(11)-methyltransferase, Precorrin-3 methylase.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: PMIP_ASPFC
Sequence: MKDQLLVPLRRRPWTCQKCLQRLQLPRHQTRRSFETAASPFPRPLDSLPADYARTKTVDDDTLRRVFDSQQFWREFSQQRAAQPKPTGLVQNQYLTSPDGFRTFANVSLQKCQAIVSKVLAASTLEEYRTMARDLDRLSDLLCRVIDLSDFIRVIHPDPQVQEAATQAYALMFEYMNVLNTTTGLNDQLKKAAANPEVTSQWSDEEKIVAQILIKDFSNSAIHMPPHERQRFVNLSNDISQLGSSFVNGAEPAKSHVSVATNNLRGLDPILVQQIKRWNRTAAVPTTGMIPRLALRSVHDENVRREVYLASRTSSKRQLHRLEELLLKRAELAKLSGYESFAHMTLSDKMAKSPEAVSNFLTALVESNRKLVREELSQLQVMKGAPLQPWDHAYYVHQRVLQYSQARRSRELSAVPEFFSLGTVMQGLSRLFDRLYGVRLVPQEPAPGETWNPDVRRLDVVDEAGRHIAVIYCDLFSRPNKHPNPAHFTLRCSREISAEEVAECASLDQSSHPNDGMATAVDPVTQTLRQLPTIALVCDFPEPGTNGGGRPSLLSEHSVRTLFHEMGHAVHSILGQTRLQSISGTRCATDFAELPSVLMEHFATAPSVLALYARHWRTDEPLSEGMIRSMERDRTAHGSIYGAVENEAQILMALVDQAYHSRPADGGRIDSTALYQQVSQQHSSLPEPADATTPPTSWQGFFGHLYGYGATYYSYIFDRAIANKLWVDVFGAGRHAVDRAAGERYKNEVLRWGGGRSGWECVAGALGSANESNADGRLVEGGDQAMREVGRWGLGRDGVSG
What is the function of this protein?
Cleaves proteins, imported into the mitochondrion, to their mature size.  While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial intermediate peptidase, MIP, Octapeptidyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TRMFO_SINMW
Sequence: MNKLTSSYSPVHVIGGGLAGSEAAWQIAEAGVPVILHEMRGVRGTDAHKTDSLAELVCSNSFRSDDATSNAVGVLHAEMRLAGSIIMRCADLNQVPAGGALAVDREGFAEAVSAAIAAHPLITVLREEIRGLPPKEWDLAIIATGPLTAPDLADAIRAETGADALAFFDAIAPIVHADTIDMDICWHQSRYDKVGPGGTGKDYINCPLTQEEYNAFIDALIAGDKTGFKEWEGTPYFDGCLPIEVMAERGRETLRHGPMKPMGLTNAHNPSVKPYAVVQLRQDNALGTLYNMVGFQTKLKYGAQGEVFRMIPGLEKAEFARLGGLHRNTYINSPTLLDQSLTLKSRAGLRFAGQITGCEGYVESASIGLLAGRFAAAERKGASPAIPPVTTAFGALLNHITGGHIVSDDEPGKRSFQPMNVNFGLFPPLDPGALTRPEGAKRFRGKEKASAKKQAMASRALSDCATWLDKNLLIGGAATR
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT107_YEAST
Sequence: MSTSLLFEQLNFLILVAAEAELPIAHSTRKLLMDNSCNNCQIYELYNENLKDVKTDKDWFMNKFGPQTVHFVISNTINFPFYKIVYFDLLIPVVSHTWVQDSVKTKRHLRTNMYSPNPFHLLRDCQVYISKSSFNKCEYILYSDLLHLLGGTLVNYISNRTTHVIVQSPQDPIIATVSKLTFGSFSSSSTNKHTEKPLREWKFVYPIWILYHFKMAKPLKGELATLCELDMQDTSEEQLFAKWEEVIGDKQTSSSQLTLHPNKTLFKNHHFAISPDLNFFTPLYWFLKGFIEDLDGKVTPLSFSDDLKSVYQAFPDIDCYIGHSANSPILEKTKSIKPEIHVGNVSWLFYMFALQKFTPVSQCKLIHQPFHAKLFTSKELTVAYTNYFGSQRFYIQRLVEILGGLSTPELTRKNTHLITKSTIGKKFKVAKKWSLDPQNAIIVTNHMWLEQCYMNNSKLNPKDSRFQNFKLDDNMGWNIGQIGMDHSSLPTPKNLSMVTYDTQSISEKPPPTNDQMDQINDNTNVLSKKDGTPISSFENSIDEKIDKLQKISGEVAVTHSGDLERSFVSRPSRASFPVVDSKKSNLQKKDSNSDISMETEVFCEGHEKREEKEFTKPITEYDAPKKQEIREQSRKKNDIDYKKEEEETELQVQLGQRTKREIKTSKKNEKEKETNECHIEVDQMTNEKQGEESTGKLISTEDVTSKKDTDKFSHLFEGLSDNDDHINDEKPAVNSKYTTPKTSQNITSGVDTPTTAQTQVFMPSSGNSRLAKTQAAKRLHTDIESLNEFQKNFKRKRIDSEEISLSQDVERSNNNKELATKAEKILARFNELPNYDLKAVCTGCFHDGFNEVDIEILNQLGIKIFDNIKETDKLNCIFAPKILRTEKFLKSLSFEPLKFALKPEFIIDLLKQIHSKKDKLSQININLFDYEINGINESIISKTKLPTKVFERANIRCINLVNDIPGGVDTIGSVLKAHGIEKINVLRSKKCTFEDIIPNDVSKQENGGIFKYVLIVTKASQVKKFTKLINDRDKNETILIVEWNWCVESIFHLNVDFTSKKNVLYQKKNN
What is the function of this protein?
Required for resumption of chromosome replication after DNA damage, specifically in S phase.  Is recruited to chromatin in the presence of RTT109 and RTT101 in response to stalled replication forks and acts as a scaffold during DNA repair.
What are the official names of this protein?
Regulator of Ty1 transposition protein 107, Establishes silent chromatin protein 4.
What are the subcellular locations of this protein?
Nucleus. Note=Recruited to chromatin in response to replication fork stalling.
Protein: S39AD_CHICK
Sequence: MTKQKLLLNGTFSLILIVACEAQQLPRSHAASSSGPLCEKEAESWGNLLSSERLDAWICSLIGSFMVGLSGIFPLLVIPFETGAALRSEAGSRRLKQLLSFAIGGLLGNVFLHLLPEAWAYTCSAAAGEGQSFQQQKLLGLWVIIGFLTFLALEKIFLEKEEEECPGVGCDYKAPLGKIPNGSGYPPSKVAGKSQRAEKNSTQCNGSSLQSCRTDNRIKISGYLNLLANTIDNFTHGLAVAASFLVSRKVGFLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKMQLSTALGGIVGACFAICAQSPKGAGETVAWILPFTSGGFLYIALVNVVPDLLEEKNPWNSLQQILLLCTGITVMVLLAHN
What is the function of this protein?
Functions as a zinc transporter transporting Zn(2+) from the Golgi apparatus to the cytosol and thus influences the zinc level at least in areas of the cytosol.
What are the official names of this protein?
Zinc transporter ZIP13, Solute carrier family 39 member 13, Zrt- and Irt-like protein 13, ZIP-13.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: PCY1B_HUMAN
Sequence: MPVVTTDAESETGIPKSLSNEPPSETMEEIEHTCPQPRLTLTAPAPFADETNCQCQAPHEKLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPVSSPTRSRSPSRSPSPTFSWLPLKTSPPSSPKAASASISSMSEGDEDEK
What is the function of this protein?
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
What are the official names of this protein?
Choline-phosphate cytidylyltransferase B, CCT-beta, CTP:phosphocholine cytidylyltransferase B, CCT B, CT B, Phosphorylcholine transferase B.
What is the protein family that this protein belongs to?
Belongs to the cytidylyltransferase family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. Endoplasmic reticulum. SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum.
Protein: NF04_NAEFO
Sequence: KTXATLFPGHGIGPEIXQAVXPIL
What are the official names of this protein?
Unknown protein NF004 from 2D-PAGE.