PharMolix/UniProtQA huggingface dataset:
Protein: AAKG3_HUMAN
Sequence: MEPGLEHALRRTPSWSSLGGSEHQEMSFLEQENSSSWPSPAVTSSSERIRGKRRAKALRWTRQKSVEEGEPPGQGEGPRSRPAAESTGLEATFPKTTPLAQADPAGVGTPPTGWDCLPSDCTASAAGSSTDDVELATEFPATEAWECELEGLLEERPALCLSPQAPFPKLGWDDELRKPGAQIYMRFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEQHKIETWREIYLQGCFKPLVSISPNDSLFEAVYTLIKNRIHRLPVLDPVSGNVLHILTHKRLLKFLHIFGSLLPRPSFLYRTIQDLGIGTFRDLAVVLETAPILTALDIFVDRRVSALPVVNECGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA
What is the function of this protein?
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.  In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.  AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.  AMPK also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.  The AMPK gamma3 subunit is a non-catalytic subunit with a regulatory role in muscle energy metabolism (PubMed:17878938).  It mediates binding to AMP, ADP and ATP, leading to AMPK activation or inhibition: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits.  ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit.  ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
What are the official names of this protein?
5'-AMP-activated protein kinase subunit gamma-3, AMPK gamma3, AMPK subunit gamma-3.
What is the protein family that this protein belongs to?
Belongs to the 5'-AMP-activated protein kinase gamma subunit family.
Protein: LPXC_CAMHC
Sequence: MKQTTIAKKVTSVGIGLHKGEPIRLTIEPSSENTGIIFYRSDLGISFKAEPKNVVNTQMATVIGNQKGYISTVEHILSAINGYGIDNIRINVDANEIPVMDGSSISFCMMLDEAGIKNLDASKKAIIIKREVEVKEGEKFVRVSPSKSPKFDYTIKFSNPIIGTQQFAFEFSRKNYVDEIARARTFGFLKDVQMLRSMNLALGGSLENAVVIDDNKILNPDGLRYENEFVRHKILDAIGDLSLLGAPILGDYTAYAASHDLNHKLTLAILTDAKNYEMVSIDEQIAHEYAKIFA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: TE2IP_XENTR
Sequence: MAALGGLTHSRTLFVDDDGTPMSFYVPPGPLKRQLYPLITHGGGEMCRMQQPGALLLSAPGSAQGAQYVSTAYIMDCVRIDKLLDVDDYRLDGSHGRPRKSQGSKKEERAPQQKVGESSQESDQKQQAKVGGDLEEGDKLSDPGEPVNEESLGSVSSTRKKENKMDCSEAQKIGSLKSARIHQTRRNVFTEKEDVAIMLYVRENAPHRGTGVSLWKEMEQKQVVKRTWQAIKNRYFRYLKGKRNYVLPLTDDSSSQEPSDDEEECPQPITKKSRISDSTPCTEKPGVAEKTGEKLSTDTSVEGPSTEKSDAAKTSNVNLPVEERGQEVTEGAIKRSEGNKKSTEMNEEAVSASSKENQDDGADLHIFEIANLEFEVEDTPELEVPKRSFGLKEFVMGEDLPSSQSQTQVDEVSSSPDASESEGLQEALLSMMSEFKLSLCDVTQALLKNNGELAATRHFLQTGSRPDGYPIWVRKDDLDLQKDDAETLKRLIQKYGADNVAKRVAFLAS
What is the function of this protein?
Acts both as a regulator of telomere function and as a transcription regulator.  Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome).  Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2.  Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression (By similarity).
What are the official names of this protein?
Telomeric repeat-binding factor 2-interacting protein 1, TERF2-interacting telomeric protein 1, TRF2-interacting telomeric protein 1, Repressor/activator protein 1 homolog, RAP1 homolog, XtRAP1.
What is the protein family that this protein belongs to?
Belongs to the RAP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: SECA2_CORDI
Sequence: MAGFRWFWDAMGGKNTRNQTKSKNIVAQAAKRGVQFASLSDADVVARAHECAQHSDDESRADLLALLSIGAQRSLSMNPFNVQLQAVLRILEGDVIHMATGEGKTLVGAMASVGYALQGKRVHSITVNDYLAERDAEWMGDLVRYFGLTVSAVTESLNTEQRRRAYASSIVYAPVTEIGFDVLRDQLVTQRSHAVQNGADVAIVDEADSVLIDEALVPLVLAGNEPGTAPAGRITEIVRRLKENEHYSVDADRRNVSLNDKGAALLEQVLGIQSLYDDAHIGTTLVQVNLALHAQALLIRDVHYIIRDGKIALIDASKGRVAQLQRWPDGVQAAVEAKEGLVVTEGGRILDTLTLQSLMGRYPIVCGMTGTAVEATDQLRQFYDLRVSVIEPHKQSQRFDEADRVYATQAEKFRALVKEIELLHTTGQPVLIGTSDVSESEELAQALQARDITVNVLNAKNDAEEAQIIAEAGDIGRVTVSTQMAGRGTDIRLGGANEKDRDAVVAKGGLAVIGSSRHRSSRLDNQLRGRAGRQGDPGLSLFFVSLEDDVVVVGGAGEEIKALPDADGRIDSKRITDFVAHCQRVTEGQLLEIHSQTWKYNKLLADQRVIIDERRARLLDTDQAWVELSEAVPEKAHKLSDKLDPAILVQAAREVMLYHLDRCWSDHLALMDHVRESIHLRTIARETPLDEYHRIAVREFKQLAQRAVDLAVETFRDVTIDQDGAHLADAGLTRPSATWTYMVSDNPLSNNNRSVINGIGSIFR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: CYB_VIVIN
Sequence: MTNIRNSHPLVKIVNESFIDLPAPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGVYYGSYTFSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGMVSDSDKIPFHPYYTIKDILGLLFLILMLMLLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIIPLLHTSKQRSMMFRPLSQCLFWFLVADLFTLTWIGGQPVEHPFITIGQLASIFYFSILLILMPIFGTIENRLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YOPV_BACSU
Sequence: MLLDEKLDKLMKTILRLKAYKEEENLRRVIGEFHSIIDYAYEGMYIAEDMLREEESKGKEVSTY
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YopV.
Protein: RL22_EHRRW
Sequence: MSKVLVEAKGMGLRSTPYKLNLVADLIRGKPVSVAVMYLKFCKKKSARYISKVLKSAIANAQANYSVDVDNLYIKEVLVGKSFSLRRIHARARGKACRVYKHYGNVIIKLFERV
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CRIPT_CHICK
Sequence: MVCEKCERKLGTVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFAICRICKSSVHQPGSHYCQGCAYKKGICSMCGKKVLDTKNYKQTSV
What is the function of this protein?
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
Cysteine-rich PDZ-binding protein, Cysteine-rich interactor of PDZ three, Cysteine-rich interactor of PDZ3.
What is the protein family that this protein belongs to?
Belongs to the CRIPT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_PASMU
Sequence: MSIEERVKKIIVEQLGVKEDEVKPEASFVEDLGADSLDTVELVMALEEEFDIEIPDEEAEKITTVQSAIDYVQNNQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIE_BRUA2
Sequence: MYDSIMSVSARNALSRLSETVAEKGVGSASAPQAVPAAPGASFGEVLSQMTGSVSQKLQAAEATSIQGIKGDAPVRDVVSSVMEAEQSLQTAIAIRDKIVQAYLEISRMPI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: FADA_YERPE
Sequence: MENVVIIDAVRTPMGRSKGGAFRHVRAEDLSAHLMRAVISRNPGLNAAEIDDIYWGCVQQTLEQGFNIARNASLLAEIPHSVPAVTVNRLCGSSMQALHDGARAIMVGDAKISLIGGVEHMGHVPMNHGVDFHPGMGRTVAKAAGMMGLTAEMLAKIHNISRQSQDEFAFRSHQRAYAATQAGHFAKEIVATNGHDAEGVLKRFDFDEVIRPETNLSGLAALRPAFDPVNGTVTAGTSSALSDGASAMLIMSESRAKSLGLTPRARIRSMAVVGCDPSIMGYGPVPASQLALKRAGLELADIGLFELNEAFAAQSLACLKGLGLLESMDDKVNLNGGAIALGHPLGCSGARISTTLLNLMERRDVQFGLATMCIGLGQGIATVFERL
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.  Involved in the aerobic and anaerobic degradation of long-chain fatty acids (By similarity).
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_WOLPP
Sequence: MKYDFKNVEKFYQNKWDFSVSKDSKKKKCYVLEMFPYPSGKIHMGHLRNYAIGDVIARYKRARGFEVLHPIGWDAFGLPAENAARDNNINPAAWTQDNIDNMRTQLKSIGLSYNWDRELSTCEPDYYKHEQKFFLDFLKHGLAYRKESWVNWDPVDQTVLANEQVVDGKGWRSGAVVEKRKLFQWFLKITDFAEDLLHCLQSLKNWPEKVKTMQERWIGKSEGATIDFEIFGLNKKLKIFTTSPHTLFGASFLAVGAEHPIVQDLKDKEIRDFIGNMKAKGENDEKIGIYTGLNVKHPFLDKELPLYIANFVLMEYGEGAIFGCPAHDQRDFEFAQKYGLPIIPVVCEESTEILKEPYFGDGVMFNSEFLNGLMINEAKKVIIKKLEEKGIGKKTINYRLHDWGISRQRYWGCPIPIIHCKDCGIVPVPEKDLPVVLPTDVEFTSGGNPLDKHPTWKFVDCPKCGKQAERETDTFDTFFESSWYFAAFCSENKSINKDTCNRFMPVDYYIGGIEHAILHLLYSRFFCRALTKCGYFDVKEPFSTLITQGMVCHITYKDENGKWLFPEEAKELIAKGAKIQVGKVEKMSKSKKNTVDPNFIIEKYGADTARLFVLSDTPPEKDMEWSDDGVEGCFRYINKLWRMVVQLRTVNIHYDNENIVGKLLEYRKKIHKLLHGLTDDLENCRLNCVVAKFREMTNLIAEIDVKTGKSLIDEGICILIRVIEPLMPHLAENLWQEIGGEGMLYMQPWPKADESLLIDNMVTVAVQINGKLRATIKVETDLPQEELKKIATDSVSNKIDQSKIRTIYAVPNKVVNIVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPR1_BOVIN
Sequence: MPSATSHSGSGSKSSGPPPPSGSSGNEAGAGAAAPASQHPMTGTGAVQTEAMKQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLADPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKALKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPTVEDQAAEAEPEPVEEYTEQNEVESTEYVNRQFMAETQFSSGEKEQVDDWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPAQNMDIPQLVCPPVHSESRLAQPNQVSVQPEATQVPLVSSTSEGYTASQPLYQPSHATDQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSQDQPHQVTGNHQQPPQQNTGFPRSNQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSTNTPNSGYTQSQFSAPRDYSGYQRDGYQQNFKRGSGQSGPRGAPRGRGGPPRPNRGMPQMNTQQVN
What is the function of this protein?
mRNA-binding protein that acts as a regulator of mRNAs transport, translation and/or stability, and which is involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types.  Acts as an mRNA regulator by mediating formation of some phase-separated membraneless compartment: undergoes liquid-liquid phase separation upon binding to target mRNAs, leading to assemble mRNAs into cytoplasmic ribonucleoprotein granules that concentrate mRNAs with associated regulatory factors.  Undergoes liquid-liquid phase separation following phosphorylation and interaction with FMR1, promoting formation of cytoplasmic ribonucleoprotein granules that concentrate mRNAs with factors that inhibit translation and mediate deadenylation of target mRNAs.  In these cytoplasmic ribonucleoprotein granules, CAPRIN1 mediates recruitment of CNOT7 deadenylase, leading to mRNA deadenylation and degradation.  Binds directly and selectively to MYC and CCND2 mRNAs.  In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
What are the official names of this protein?
Caprin-1, Cytoplasmic activation- and proliferation-associated protein 1, RNA granule protein 105.
What is the protein family that this protein belongs to?
Belongs to the caprin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell projection, dendrite. Cell projection, lamellipodium. Note=Associated with RNA granules (By similarity). At the leading edge of migrating fibroblasts, colocalizes with DDX3X (By similarity).
Protein: NU4LM_MACFA
Sequence: MTPTYMNIMLAFTISLLGMLTYRSHLVASLLCLEGMMMSLFIMATLIASNTHFPLVNIMPIILLVFAACETAVGLALLISISNTYGLDYVHNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y612_SHEFN
Sequence: MIVIEQILSKQDVGAYRQQLAECPWGDGRKTAMGMAASVKNNNQADAQHANVRQLANQLLARIGETPKIVSAALPHKIFPPCFNRYNETEEYGYHVDAAIMRIPNTSEVIRSDVSMTVFLSEPEEYDGGELVIATEFGQQQIKLPAGYAVVYPSSSLHKVTAVTRGQRIAAITWMQSMVADVTLRQTLYQLDQSIQNLIKANNTDRAELDNLHNVYHNLIRQFTQL
What are the official names of this protein?
PKHD-type hydroxylase Sfri_0612.
Protein: RL6_METS4
Sequence: MSRVGKKPVTVPAGVTATVDGQNVKIKGAKGELSFRVPDLVEVSHADGAISVQPRSQTKEARAMWGLSRAQVANLIEGVTKGFEKKLEINGVGYRAAVAGKVLKLSLGYSHDVEYEIPAGITITTPRPVEIIVAGIDKQRVGQIAAEIREYRGPEPYKGKGVKYSDEFIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ETFB_METME
Sequence: MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASLRGIKQAATKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEFKGA
What is the function of this protein?
Heterodimeric electron transfer flavoprotein that accepts electrons from trimethylamine dehydrogenase (PubMed:7798207).  It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (Probable).  EtfB binds an AMP molecule that probably has a purely structural role (PubMed:7798207).
What are the official names of this protein?
Electron transfer flavoprotein subunit beta, Beta-ETF, Electron transfer flavoprotein small subunit, ETFSS.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: REM23_ARATH
Sequence: MASNPDFLWCKEERKQESFFKVLKRSDMSSEDTRAIPYDFVINFSDNELSGDMKFRVQWGNSWKVKISKNPRFYFMEKSGWEKFVIDNALGDHEFLTFTHKGQMSFTVKIFNKDGKEMMQPPQSRASFASSSRVKTEQDVKREEEVLVSSDSRSRGPTTAAETNRGGSYKRKLNFGKKKAEETQTYKRTERTQNSKRTERVVSKERVYAGEPSSSVAGFKIFISKSYIKSLAIPKPFGNYMPKEKTRVKIHHPDGEKTWKVVFVVKERGQIFSGGWKRLCKEYPVVFGDTCKFTLITPLELLLVVSKP
What are the official names of this protein?
B3 domain-containing protein REM23, Protein REPRODUCTIVE MERISTEM 23.
What are the subcellular locations of this protein?
Nucleus.
Protein: RXRGA_DANRE
Sequence: MDNNDTYLHLSSSLQVAHGHLSSPPSQPPLSSMVSHHHPSIINGLGSPYSVITSSSLGSPSASMPTTSNMGYGALNSPQMNSLNSVSSSEDIKPPPGLAGLGSYPCGSPGSLSKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYTCRDNKDCQIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGRERSDNEVDSSSSFNEEMPVEKILDAELAVEPKTEAYMESSMSNSTNDPVTNICQAADKQLFTLVEWAKRIPHFSDLPLDDQVILLRAGWNELLIASFSHRSVTVKDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDAKGLSNPSEVEALREKVYASLEGYTKHNYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQIT
What is the function of this protein?
Receptor for retinoic acid.  Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes.  The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5.  The high affinity ligand for rxrs is 9-cis retinoic acid (By similarity).
What are the official names of this protein?
Retinoic acid receptor RXR-gamma-A, Nuclear receptor subfamily 2 group B member 3-A, Retinoic acid receptor RXR-alpha, Retinoid X receptor alpha, Retinoid X receptor gamma-A.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL22_VIBVY
Sequence: MEAIAKHNFARISPQKARLVADLIRGKSVDQALEILTFSNKKAAVLVKKVLESAIANAEHNEGADIDDLNVAKIFVDEGPTMKRIMPRAKGRADRILKRSSHITVVVADR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: VAC14_RAT
Sequence: MNPEKDFAPLTPNIVRALNDKLYEKRKVAALEIEKLVRDFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESSKFDLVGFIPLLRERIYSNNQYARQFIISWILVLVSVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDEPDEPKSVAQKQTEPNPEDSLPKQEGTASGGASGPCDSSFGSGISVFTSASTDRAPVTLHLDGIVQVLNCHLSDTTIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVVLKDLEVLAEIASSPAGQTDDPGAPDGPDLQVNHSELQVPTSGRANLLNPPNTKGLECSPSTPTMNSYFYKFMINLLQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLMKALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDCLKAAPKSQKGDSPSIDYTELLQHFEKVQKQHLEVRHQRSGRGDHLDRRVVL
What is the function of this protein?
Scaffold protein component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Pentamerizes into a star-shaped structure and nucleates the assembly of the complex.  The pentamer binds a single copy each of PIKFYVE and FIG4 and coordinates both PIKfyve kinase activity and FIG4 phosphatase activity, being required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P).  Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
What are the official names of this protein?
Protein VAC14 homolog.
What is the protein family that this protein belongs to?
Belongs to the VAC14 family.
What are the subcellular locations of this protein?
Endosome membrane. Microsome membrane. Note=Mainly associated with membranes of the late endocytic pathway.
Protein: RPIA_PSEAE
Sequence: MNQDQLKQAVAQAAVDHILPHLDSKSIVGVGTGSTANFFIDALARHKAEFDGAVASSEATAKRLKEHGIPVYELNTVSELEFYVDGADESNERLELIKGGGAALTREKIVAAVAKTFICIADASKLVPILGQFPLPVEVIPMARSHVARQLVKLGGDPVYREGVLTDNGNIILDVHNLRIDSPVELEEKINAIVGVVTNGLFAARPADLLLLGTADGVKTLKA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: Y1604_HAEIN
Sequence: MEIISQYGSWLVWITAVFGFFMAFGIGANDVSNSMGTSVGSGTITAKQAIIIALIFESAGAYLAGGEVTQTIKSGVIEPIQFVDTPDILALGMLSTLFASGAWLFIATKMGWPVSGTHTIIGAIIGFACITIGPSSVDWSKIGSIVGSWFVTPVIAGILAYAIFASTQKLIFDTEQPLKNAQKYGPYYMGITVFVLCIVTMKKGLKHVGLNLSNSETLIISLAISLIGMFFFHFYFKSKIFTQSANKGTFGAVEKVFSILMLLTACAMAFAHGSNDVANAIGPLSAVVSIVNEGGKIVSGGALTWWILPLGALGIAVGLITMGQKVMATVGSGITDLTPSRGFAAQFATAMTVVVASGTGLPISTTQTLVGAILGIGFARGIAALNLTVIRNIISSWIVTLPAGAFFAIIIFYVLRTIFN
What is the function of this protein?
Potential transporter for phosphate.
What are the official names of this protein?
Putative phosphate permease HI_1604.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NANE_BORBU
Sequence: MIIIVKIKRGLIVSCQALENEPLHSSFIMSKMALAAKIGGAIGIRANGVNDISQIKLEVDLPIIGIIKKNYNNCDVFITPTMKEIDELCNEGVDIIALDATFRNRPDGVLLDDFFENIKKKYPKQCLMADISSLDEAINADKLGFDFIGTTLYGYTKNTNGLNIADNDFNFLRTLLNSNLKSTLIVEGKIDTPLKAQKCFEMGVDLVVVGGAITRPAEITKKFVEKINQIKK
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: ASTB_SHISS
Sequence: MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQGLLKMKTLADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSSASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFSVHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREASEAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLANLRARVNGFMAIEVPATQVSVSDAVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGYLNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFNALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.