PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_MOOTA
Sequence: MIGYLRGRLHLVTPEGILLETGGIGWLVRTVTNRSWPAPGTEIAVYTQLVVREDAMELYGFTRPEELHLFTLLRGVNGIGPRGALQILGAAKPEQLSRAIAAGDSAFLTALPGIGAKKAQRLLLELKDAVLKSGLVDGTETEAIPAGGGDNDEALAALLALGYSREEIGPILARVRQELGNAAPTTAVLQAVLKTFGRGGGD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: BPT_XANCP
Sequence: MAIHADTHDDLRLFQTGEHACGYWSDRQARDLVLDPHDPRLGALYPQALAWGFRRSGDLVYRPHCERCRACVPVRIAVDAFHPDRSQRRCLARNQDLVVRVVAAERTEEQLALYRQYLQHRHPGGGMDTHGAAEFDQFLIGGWSHGRFLEIREPAVDHVPGRLLAVAVTDVTEHALSAVYTFYAPDAAARSLGTFAILEQIQWARRERRAHLYLGYWIEGHAKMNYKRRFNALEAYDGRHWRGLPAAQGSAR
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_NEIPO
Sequence: AIMKMDGSQQEENLEVISTGSLGLDLALGVGGLPRGRIVEIFGPESSGKTTLCLEAVAQCQKNGGVCAFVDAEHAFDPVYARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGIDMVVVDSVAALVPKAEIEGDMGDSHVGLQARLMSQALRKLTGHIKKTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFYSSVRLDIRRTGSIKKGEEVLGNETRVKVIKNKVAPPFRQAEFDILYGEGISWEGELIDIGVKNDIINKSGAWYSYNGAK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_PHOLL
Sequence: MIDDDGYRPNVGIVICNRQGQVLWARRYGQHSWQFPQGGINPGESPEQAMYRELYEEVGLGRKDVRILASTRNWLRYKLPKRLVRWDTRPVCIGQKQRWFLLQLLCNEEDINVQHSNTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMPMQESVSLPRSSYSYRRKRS
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RS5_RICPR
Sequence: MSKVKKNEEALSEVLVDVNRVTKVVKGGRRFAFSAYVVVGDKAGRVGAGHGKAKEVNEARGKAKQAAKKRMMKVPLYQNRTIHHDVVGKSGAAKVILRRAKAGTGVIAGGSMRAIFDSLGVHDIVAKSIGSTNVYAMISATFDALNKLASPKSIAIRRDKKVHEISIKSYIQVNE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RS19_STRPI
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SDHA_RICBR
Sequence: MTKSYNIIHHKFDVIVVGAGGAGLRAAFGMAEEGLNTACISKLFPTRSHTVAAQGGISAALGNMGADDWRWHMYDTVKGSDWLGDQDAIEYMCKNAPDAILELEHYGVPFSRTEEGKIYQRPFGGMTTEYGKGKAAQRTCAAADRTGHAILHTLYQQSLKHKVQFFIEYFAIDLLMENGECRGVVAWNLDDGSLHCFRAHNVVLATGGYGRAYFSATSAHTCTGDGGGMAIRAGLPLQDMEFVQFHPTGIYSAGCLITEGARGEGGYLVNANGERFMERYAPAAKDLASRDVVSRAMTIEIREGRGVGEHKDHVFLHLNHLSPEIVHSRLPGISETAKIFAGVDVTKEPIPVLPTVHYNMGGIPTNYHGQVIIKDGKNHNSVVKGLMSIGEAACVSVHGANRLGSNSLLDLVVFGRSAALKAAELIKPASPHKPVSEEALEKIISRFDKIRHSSGNISVADLRLKMQRTMQSHASVFRTQEVLDEGAEMISEIRSGYKDIKVNDKSLIWNSDLVEALELDNLLDQALVTVYSAAARKESRGAHAREDYPDRNDKEWMQHTLSGVDEAGKVVLDYKPVTLTTLSDEVKAIPPAKRVY
What are the official names of this protein?
Succinate dehydrogenase flavoprotein subunit.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROB_LACLS
Sequence: MKLNVNLPDHPYDVIIENGALANIGNWVSSLWKKQKIVLISDNHVNGLYGQKVVEQLEKSGFEVETFEFPEGEASKNLLTAEKAWNFCAEFGLTRSDGIIAFGGGVTGDLAGFVASTYMRGIHFLQIPTSLTAQVDSSIGGKTGINSKMAKNMIGTFTQPDGVLIDPEVLKTLGQREFCEGLGEVIKCALIADKALWNLLTDLSAKDLLENFAKIEEIIYRSCEVKRKVVVDDVLDNGVRLYLNFGHTIGHAVENTAGYGKVMHGEAVAIGMVQISKIAEKKGLMPLGITDEIRKMVKKYGLPDDYQPWDEALLFKALTHDKKARGTIIKTVIVPEIGTAKINEVTFEEMKEYLKK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTD_SODGM
Sequence: MKKRLPTLLASLIGSALYSQQALADLADQCLLGVPAYTKPLVSGDANSLPVHIQADKAAANYPEHALFSGNVYIEQGNSTLTADEVQLTQRQEQNNAPLRTATATGNVNYSSNEIKLQGPKAWSNLNTKDTDVYQGNYQIVGRQGRGDADTMKQRGDNRYTVLENGSFTSCLPGDDSWSVVGSEVIHDREEQVAEIWNARFKIGKVPVFYSPYLQIPVGDKRRSGFLIPNAKYGSNNGFEFSAPYYLNLAPNYDATIMPNYMSKRGTQIQTEFRYHTTPGEGLVEFDWLPKDRVYSSEHASDGDSDRWLLYWRHNGVMDQVWRFNVDYTKVSDSNYFDDLDSKYGSTTDGYATQKFSFGYADENWDTALSYKQFQVFDTNSSDAYRTAPQLDVTYYKNDVGPFDFKVFSQAAKFTNVNNSYPEATRLHIEPTLNLPLANRWGSLNTEAKLMATHYQQENIDEYNENTGTGRHLKGSVNRVLPQFKTDGKMVFERDMDYAPDYTQTLEPRLQYLYVPYRNQNDIGVYDSTILQTDYSGLFRDRTYSGLDRISSANQLAGGVTTRIYDDQRAERFNASVGQIYYFSRPRTGDITGTWDNYDNTGSVVWAGDSYWRISNQWGIRGGLQYDSRLNSVALGDAVLEYRRDENRILQLNYHYASPQYIEQMLSDISHTGYQQGISQVGVTGSWQLVDRWSLVGAYYYDTKANQPADQLVGLQYNTCCWAINVGYERKITGWNSTDSSSQYDNKVSFNIELRGLSSNYGLGTDKMLASGILPYQRAF
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: H2A5_ORYSI
Sequence: MDAAGAGAGGKLKKGAAGRKAGGPRKKAVSRSVKAGLQFPVGRIGRYLKKGRYAQRIGTGAPVYLAAVLEYLAAEVLELAGNAARDNKKNRIIPRHVLLAIRNDEELGKLLAGVTIAHGGVLPNINPVLLPKKTAEKAAAAGKEAKSPKKAAGKSPKKA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Probable histone H2A.5.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y944_METJA
Sequence: MLIGILSKKYVKEILELLNEKGELHFSQIHKEIPTHMSSLNRTLNELVKLGLISKRKEDNKQALPKTYYKLTPLGKKALLLYEVEKIIENSKNNQNIIIQIINGKNHNIINAKIVNIHNK
What are the official names of this protein?
Uncharacterized protein MJ0944.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0361.
Protein: RPOY_LIMRD
Sequence: MTFKVYYQADKTKRPVRENTQSLYIEADSEAEALLMVEHNTDYNIEFVEQLDEKALAYEKQNPNFKLTTF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: VE6_HPV25
Sequence: MATANAEQSIGPPEQAQVIQPPLPATITDLAALLEIPLDDCLVPCNFCGNFLTYLEICEFDEKRLSLIWKEYLVYACCRCCCTATATFEFNEFYESTVTGREIEDVTGKSIFDIDVRCQTCMKYLDAIEKLDICGRRRPFHLVRGSWKGICRLCKHFYNDW
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: PROA_BURO0
Sequence: MDIDQYMTDLGRRARHASRAMARASTAAKNAALDAVARAIERDAQALKDANARDVARAREKGLDAAFVDRLTLSDKALKTMVEGLRQVASLADPIGEIGNLKFRPSGIQVGQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNATILRGGSEALESNAALAKLIGEGLEAAGLPQDAVQVVATADRAAVGKLITMTEYVDVIVPRGGKSLIERLINEARVPMIKHLDGICHVYVDDRADLAKALTVCDNAKTHRYGTCNTMETLLVASGIAAKLLPRLGKLYRDKQVELRVDAAARAVLADAGVGPLVDATEEDWHTEYLAPVLAIKVVDGLDAAIEHINHYGSHHTDAIVTEDHDRAMRFLREVDSASVMVNASTRFADGFEFGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGHGEGRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
Protein: VRPI_BPT7
Sequence: MSNVNTGSLSVDNKKFWATVESSEHSFEVPIYAETLDEALELAEWQYVPAGFEVTRVRPCVAPK
What is the function of this protein?
Acts as an inhibitor of bacterial RNA polymerase by interacting with RpoC subunit and thus preventing promoter recognition by RpoE.  Non-DNA-binding transcription factor that plays a role in the transcriptional switch that abolishes transcription of the viral early genes (class I) by the host RNA polymerase but allows transcription of late genes (class II and class III) by T7 RNA polymerase.
What are the official names of this protein?
Bacterial RNA polymerase inhibitor, Gene product 2, Gp2.
Protein: GLMU_PSEPG
Sequence: MSLDIVILAAGQGTRMRSALPKVLHPVAGNSMLGHVIHSARQLQPQGIHVVIGHGAELVRERLAADDLNFVMQDKQLGTGHAVAQALPALTADTVLVLYGDVPLIEVETLQRLLAKASDQQLGLLTVTLEDPTGYGRIVRDEQGQVTAIVEHKDANDAQKAIKEGNTGILALPAARLADWMGRLSNNNAQGEYYLTDVIAMAVADGLVVATEQPHDPMEVQGANDRRQLSELERHYQLREGRRLMAQGVTLRDPARFDVRGEVTVGRDVLIDINVILEGKVVIEDDVQIGPNCVIKNTTLRKGAVVKANSHLEGAVMGEGSDAGPFARLRPGSVLDAKAHVGNFVELKNAHLGEGAKVGHLTYLGDAEIGARTNIGAGTITCNYDGANKFKTVMGEDVFIGSNNSLVAPVEIKAGATTAAGSTITQTVEAGDLAVARARQRNISGWKRPEKTKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3B_SPICI
Sequence: MIVNIKRDKILDELLKVSRIISQKTLIPSLLGILIEVKKDKITFTTSDGDTSIKSEIMGNDLNITRIGSVLIKNKFIVEVIRKIEDEFITLEVVEGNLIKIKANNFDSVLNTLNSADYPHLSFETEGKEIIFTSTVLKEIISQTSFAIGEKEKRIVFNGLNIKTDQNNKELIITATDSFRLSCKKIDYSNNYNFDVIIPGKFINEIGRLISENDQVSELLLIIINCKQKIIEGKYPDTSKVIRTSFNTSLTINNRAIIKIIERRSVLSNETMTTIVTLKIKEQKVLVTSFTQEIGNTEEEIRDFKVEGTDQIIAFNSKYILDALKAFKTKEITIKMIDERKPLIITANDDQTLQQLVLPIRSY
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EZRA_STRA5
Sequence: MSSGIILLLVAIVLLVIIAYVVGVVIRKRNDTLIANLETRKQELVDLPVQEEIEQVKLLHLIGQSQSTFREWNQKWTDLSTNSFKDIDFHLVEAENLNDSFNFVRAKHEIDNVDSQLTIIEEDIVSIREALEVLKEQEEKNSARVTHALDLYETLQKSISEKEDNYGTTMPEIEKQLKNIEAEFSHFVTLNSTGDPIEASEVLNKAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKDIEQRFQEVREAIRSNSDGLVSLDLDRARDENEHIQEKIDKLYDIFEREIAAYKVAHKDSKIIPQFLAHAKSNNEQLGHEIKRLSAKYILNENESLSLRSFTNDLEEIETKVLPSVENFGQEASPYTHLQILFERTLKTLTTVEENQMEVFEAVKTIESVETRARQNMDKYVNKLHMIKRFMEKRNLPGIPQDFLSTFFTTSSQIEALINELSRGRIDIEAVSRLNDVTTNAIANLEQATYLVVQDATLTEQLLQYSNRYRSFEQNVQKSFEQALYLFEVEHNYKASFDEISYALETVEPGVTDRFVTSYEKTQERIRF
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: FLA3_SPIAU
Sequence: MIINHNMSAINANRVLGBT
What is the function of this protein?
Component of the core of the flagella.
What are the official names of this protein?
Flagellar filament 32 kDa core protein, 32 kDa minor core flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Periplasmic flagellum. Periplasm.
Protein: YQJA_ECOL6
Sequence: MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLPAAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNWLSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMSGLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGNRG
What are the official names of this protein?
Inner membrane protein YqjA.
What is the protein family that this protein belongs to?
Belongs to the DedA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSAB_ANGEV
Sequence: MASRFPKFSQGLSQDPTTRRIWFGIATAHDFESHDDMTEERLYQKIFASHFGQLAVIFLWTSGNLFHVAWQGNFEAWGQDPLHVRPIAHAIWDPHFGQPAVEAYTRGGASGPVNIAYSGVYQWWYTIGLRTNQDLYTGALFLLALSALFLIAGWLHLQPKWKPGLSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPESRGEHVRWDNLLTALPHPQGLGPFLSGQWSVYAQNPDSTNHLFGTSQGAGTGILTFLGGFHPQTQSLWLTDIAHHHLAIAVVFIIAGHMYRTNFGIGHSIKEILEAHTPPGGRLGRGHKGLYDTINNSLHFQLGLALAALGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNRDNVLARMLEHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPVFAQWIQSTHGKALYGFDVLLSSADSPAFTAGQSLWLPGWLDAINNNSNSLFLTIGPGDFLVHHAIALGLHTTTSIPVKGALDARGSKLMPDKKEFGYSFPCDGPGRGGTCDISAWDAFYLSVFWMLNTIGWVTFYWHWKHITLWQGNVAQFDESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWAIGFMFLISWRGYWQELIETLAWAHERTPLANLVRWKDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: WCAB_ECOLI
Sequence: MLEDLRANSWSLRPCCMVLAYRVAHFCSVWRKKNVLNNLWAAPLLVLYRIITECFFGYEIQAAATIGRRFTIHHGYAVVINKNVVAGDDFTIRHGVTIGNRGADNMACPHIGNGVELGANVIILGDITLGNNVTVGAGSVVLDSVPDNALVVGEKARVKVIK
What are the official names of this protein?
Putative colanic acid biosynthesis acetyltransferase WcaB.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: CMOB_GLAP5
Sequence: MIDFRPFYQQIATSPLSAWLETLPLQLKQWEKQTHGDYAKWAKMLDHLPSLPCEVNLADKVEARLVEPLSAGETQRLVHHLKQLMPWRKGPYHLYGVHIDCEWRSDFKWDRVLPHLSPLKDRLILDVGCGSGYHMWRMVGEGAKMVVGIDPTELFLCQFEAVRKLLNNDRRANLIPLGIEQMQPLQAFDTVFSMGVLYHRKSPLDHLAQLKNQLVKGGELVLETLVIDGDINDVLVPADRYAKMKNVYFIPSVPALINWLEKVGFKNVRCVDEAVTTSEEQRKTDWLENETLVDFLDPQDHSKTIEGYPAPKRAVIIATN
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: HEMA_I36A0
Sequence: MKARLLVLLCALAATDADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGKCNIAGWLLGNPECDPLLPARSWSYIVETPNSENGICYPGAFIDYEELREQLSSVSSFERFEIFPKESSWPNHNTNIGVTAACSHAGKSSFYRNLLWLTKKGGSYPKLKNSYVNKKGKEVLVLWGIHHPSNSKDQQTLYQNENAYVSVVSSNYNRRFTPEIAERPEVRDQAGRMNYYWTLLEPGDTIMFEANGNLVAPWYAFALSRGFGSGIITSNASMHECNTKCQTPQGAINSSLPFQNIHPVTIGECPKYVRSAKLRMVTGLRNIPSIQSRGLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAINGITNKVNSVIEKMNTQFTAVGKEFNNLEKRMENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVKNLYEKVKSQLKNNAKEIGNGCFEFYHKCDNECMESVRNGTYDYPKYSEESKLNREKIDGVKLESMGVYQILAIYSTVASSLVLLVSLGAISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: TRM3_HHV6Z
Sequence: MLRTCDITHIKNNYEAIIWKGERNCSTISTKYPNSAIFYKKRFIMLTPELGFAHSYNQQVKPLYTFCEKQRHLKNRKPLTILPSLTRKLQEMKFLPASDKSFESQYTEFLESFKILYREPLFLQIDGFIKDFRKWIKGEFNDFGDTRKIQLEPFQKNILIHVIFFIAVTKLPALANRVINYLTHVFDIEFVNESTLNTLKQKTNVFLVPRRHGKTWFIVPIISFLLKNIEGISIGYVAHQKHVSHFVMKEVEFKCRRMFPEKTITCLDNVITIDHQNIKSTALFASCYNTHSIRGQSFNLLIVDESHFIKKDAFSTILGFLPQASTKILFISSTNSGNHSTSFLMKLNNSPFEMLSVVSYVCEDHAHMLNERGNATACSCYRLHKPKFISINAEVKKTANLFLEGAFIHEIMGGATCNVINDVLITEQGQTEFEFFRYSTINKNLIPFLGKDLYVYLDPAYTGNRRASGTGIAAIGTYLDQYIVYGMEHYFLESLMTSSDTAIAECAAHMILSILDLHPFFTEVKIIIEGNSNQASAVKIACIIKENITANKSIQVTFFHTPDQNQIAQPFYLLGKEKKLAVEFFISNFNSGNIKASQELISFTIKITYDPVEYALEQIRNIHQISVNNYITYSAKKQACSDDLIIAIIMAIYVCSGNSSASFREI
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 3, Terminase large subunit.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM3 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Responsible for the nuclear localization of the two others subunits TRM1 and TRM2.
Protein: RL13_RHIEC
Sequence: MATFSQKPAEVEKKWVIIDAEGLVVGRLASIIAMRLRGKHKATFTPHVDDGDNVIVINADKVVFTGKKYSDKVYYWHTGYAGGIKERTARQIIEGRFPERVLEKAVERMVPRGPLGRRQMKNLRVYAGPNHPHEAQQPVALDVAALNKKNVRSA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RNPA_STAAC
Sequence: MEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RS8_HAEIE
Sequence: MSMQDPIADMLTRIRNGQAANKVAINMPSSKLKVAIANVLAAEGYIESVKVLEGAKPELEITLKYFQGKPVVESIQRVSRPGLRIYKRKDELPKVMGGLGVAVISTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.