PharMolix/UniProtQA huggingface dataset:
Protein: LTOR4_DICDI
Sequence: MSAPDILKDFKGSLTIEQDGSISSASGILQESFYNNKEFASTIISMLHDVNKITSSNNQEFKRMTVSFSEQTFIVTAIGTKIYVVVQ
What is the function of this protein?
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids.  As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity).
What are the official names of this protein?
Ragulator complex protein LAMTOR4 homolog, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR4 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: NUOA_PSEE4
Sequence: MSDSAGLIAHNWGFAIFLLGVVGLCAFMLGLSSLLGSKAWGRAKNEPFESGMLPVGSARLRLSAKFYLVAMLFVIFDIEALFLYAWSVSVRESGWTGFVEALVFIAILLAGLVYLWRVGALDWAPEGRRKRQAKLKQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATC_STRS7
Sequence: MKISEEEVRHVAALSKLSFSESETIEFATTLSKIVDMVELLNEVDTTGVAITTTMADKKNIMRADIAETGVDRKFLFQNVPEKENHFIKVPAILDDGGDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: T2R38_PANTR
Sequence: MLTLTRIHTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQPLSNSDCVLLCLSISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSKLIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNTRLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRDSRDPSLEAHIKALKSLVSFFCFFVISSCAAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAVLISGNAKLRRAVTTILLWAQSSLKVRADHKADSRTLC
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 38, T2R38.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y3315_METNO
Sequence: MRITWFGHSAFRLDFGASHVLIDPFFTGNPAFEGGDAARASAVEGATHILITHGHGDHVGDTLAVAGETGAKVVTNYDLCMWLASKGLTNFDPMNTGGTTDQGAFRVTLVHADHSAGMSEAGVTVPLGLPNGIIVRAAGEPTVYHMGDTDIFGDMALIQEIYRPDVLMVPIGDRFTMGAETAALAVRKFFAPKAVIPCHYGSFPIIAPSADAFVSALDGSGIQVVVPHKGTAVTIP
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Mnod_3315.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: TASP1_ARATH
Sequence: MMAGDGADQSRRFFVAVHVGAGYHAAANEKALRSVMRRACLAASTILRQDSGECIDAVSAAIQVLEDDPSTNAGRGSNLTEDGHVECDASLMDGDSGMFGGVGAVPGVRNAIKIAALLVKEQITGSTLLGRIPPMLLVGEGARRWGKSKSVLIPGTVTEADQWLVTERARNQWRRFKAMLSEVGAKSILSAEEHPRGTENNETCEENVSSCAAADEDKIMDTVGVICVDNEGHIACGSSSGGIAMKISGRVGLAATYGSGCWASSKGPFGAPFLVGCCVSGAGEYLMRGFAARECCTSLALSQAGPASAAMKVLRSVMHQESSKIGTADKTAGILVVQADASVVVPGSKPELNAVEIAAAYSSLSFGVGYYGNSIEKPKISILRTRRQMSEAGVDHFEARIDLRPTCC
What are the official names of this protein?
Putative threonine aspartase, Taspase-1.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
Protein: TKTI1_MACFA
Sequence: MQTLRREAARPYVPSGTLEASFPAPLYSDDYLSLEGPRWPLVIRQATRWKYTPMGRDAAGQLWYTGLTNSDTREAWYNLPLDPASPFREAYNRWHGCYQRREHTMPSAYTQHLRETAWHDPIIPAQYQVPSTRWGSTLWKDRPIRGKEYVINRNRYGVEPLWRASDYVPSLSAPQRPPGTTQNYREWGLEPYCPSTCQRPLPSSTPMPR
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.  Located at the center of the tektin bundle where may function to recruit tektins or stabilize the bundle.
What are the official names of this protein?
Tektin bundle-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: LNT_THEVB
Sequence: MWRLPPKSNANAKVLSRWLLFVGLGIAGWGTQLALPPVSGWFLAFVGIVPLWWQCQVLAPLWAAIAGLCWGWGFYGSSLVWVWDLHPLTWIGIDPVPSWLISRGIWLCLSSWGAVLSGSWALLMARYGVRRSAPWQLLWGVTLWCALEALWSHSPLWWISLSLTQSPGGLVQLGRLAGPTTITAVVMTVNGLVTLSLRQQKWARVGLAMTLVAAIALNGVLSVRVMADRGEPLRVGLIQGNIPTREKLTPEGIRRAWQVYLQGYHQLVSWGVDAVLTPEGALPILWQPQQMNPITEAVREAGVPLWLGTFMETAGGSHQVLLSLDGNGEIDSHYGKVNLVPLGEYIPPWLGGVVQRLSTLRSPLIPGDPEQVFTTPWGNAVVLICFESAFSHRSRWQLVHGGQFILSVANDDPYHRQLMTQHHGHDVLRAVEGDRWLVRCTNTGLSAVIAPTGETLWLSKADEFVIYAATIFRRQTETLYTRYGDWLLPLLLGMLSLSVLRQRGWH
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUCB1_BOVIN
Sequence: MPPSGPRAALFLLPSLLLLRAVLAVPLERGAPKEENPATESPDTGLYYHRYLQEVINVLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELKRQEVSRLRMLLKAKMDAQQEPNIQLDHLNLLKQFEHLDPQNQHTFEARDLELLIQTATRDLAQYDAAHHEEFKRYEMLKEHERRRYLESLGEEQRKEAERKLEEQQRRHREHPKVNVPGSQAQLKEVWEELDGLDPNRFNPKTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEDDDMREMEEERLRMREHVMKNVDTNQDRLVTLEEFLASTQRKEFGDTGEGWEQGKAGVPLPMAPVLTLQTVEMHPAYTEEELRRFEEELAAREAELNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLQMEQRKQQQQSHNNPAPGPEGQLKFHPDTDDVPVPAPAGDQKDVDASEKKVPEQTPEPPQLDSQHL
What is the function of this protein?
Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis (PubMed:7890746).  Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins) (By similarity).
What are the official names of this protein?
Nucleobindin-1.
What is the protein family that this protein belongs to?
Belongs to the nucleobindin family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Peripheral membrane protein; Lumenal side. Cytoplasm. Secreted. Note=A small fraction of the protein may be cytoplasmic.
Protein: LPXD_AROAE
Sequence: MFRLDELVERLGGELLGDPATAVRRVATLEQAGEGDLAFLANPKYQSRLAACGASAVILAPAARDLTGLPRIVTADPYIYFARVAQLFNPPEAFVPGVHPAASVASPVPASVTIAAGASIDVDVELGEHVVIGPGCRIGRGARIGAGSRLNANVTIYHDCVLGRDCIVHAGAVIGADGFGFARERDGSWVKIPQVGRVVIGDDVEIGANTTIDRGALDDTVISGGVKLDNQIQIGHNVRIGAHTAIAGCVGIAGSTTIGARCMIGGQAGIIGHLEIVDDVVVSAGTLVTKSIRRPGVYTANLPVQGHAEWVKNFAHLRHLDALVDRIRALEERKAR
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: Y1935_RHIE6
Sequence: MAKRPAATSSNDELPFATEEPVADERSFFGGRPQNPTAPNARAALPASLSGPEHYHGHRERLRDRFREQGDTALADYEILELLLFRLIPRRDTKPIAKALIDRFGSLSGVFGAPAGLLTEVKGVGENVALDLKLISTVAHRTLKSEIRSKQVLSSWSSVIQYCHAAMAHETREQFRILFLDKRNVLIADEVQGRGTVDHTPVYPREVVKRALELSATAIILVHNHPSGDPTPSRADIDMTKVIIEAAKALDITVHDHIIIGKDGHVSLKGLKLI
What are the official names of this protein?
UPF0758 protein RHECIAT_CH0001935.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: YCEI_SALPB
Sequence: MKKNLLGFTLASLLFTTGSAVAAEYKIDKEGQHAFVNFRIQHLGYSWLYGTFKDFDGTFTFDEKNPSADKVNVTINTNSVDTNHAERDKHLRSAEFLNVAKFPQATFTSTSVKKEGDELDITGNLTLNGVTKPVTLEAKLMGQGDDPWGGKRAGFEAEGKIKLKDFNITTDLGPASQEVELIISVEGVQQK
What are the official names of this protein?
Protein YceI.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: TOLB_SALEP
Sequence: MKQALRVAFGFLMLWAAVLHAEVRIEITQGVDSARPIGVVPFKWAGPGAAPEDIGGIVAADLRNSGKFNPLDRSRLPQQPATAQEVQPTAWSALGIDAVVVGQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGTKLAFALSKTGSLNLYVMDLASGQIRQITDGRSNNTEPTWFPDSQTLAFTSDQAGRPQVYKMNINGGAAQRITWEGSQNQDADVSSDGKFMVMVSSNNGQQHIAKQDLVTGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKSPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYH_ERWT9
Sequence: MAKNIQAIRGMNDYLPADTAVWQRVEQILKQVLSSYGFSEIRMPIVEQTPLFKRAIGEVTDVVEKEMYTFDDRNGESLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRYERPQKGRYRQFHQIGAEVFGLQGPDIDAELIMMTARWWKALGIADHVSLELNSIGSLEARANYRNALVAFLEQHIEVLDEDCKRRMYSNPLRVLDSKNPDIQALLNDAPALGDYLDDESREHFAGLCHQLDAAGIAYRVNQRLVRGLDYYNRTVFEWVTDSLGAQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFEPMRVVDVYVIASGDGVQSAAMLLAERLRDALPELKLMTNFGGGNFKKQFARADKWGARIALVLGEDEVANKQLVIKDLRNGEQQTLAQSDAAATLAALLQL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS64_YEAST
Sequence: MVELEKRRRPPPQLQHSPYVRDQSNSQGMTKTPETSPPKRPMGRARSNSRSSGSRSNVDIDQYTIPPGLDLLPTASSPPSVHQVSQQQQLSPILANKIRSPFENQSQDQNDNSIDPTPAGQVTIPVEAVSPPALDELSKFQNGSTETLFRTGSPRKKHTHIIILKSLNATFETKFLVVPFKPDGLKLGRPVTNSVNKNNSGSKRDLFSQQVRPDNGNFDSRVLSRNHACLSCDPTSGKIYIRDLKSSNGTFVNGVKIRQNDVELKVGDTVDLGTDIDSKFEHRKISAYVEEISVIPLMNTVSDPTNLVMKKQDHTNKNNGNSTNINGIKIDRGHHNQHIPIRSHLKENYTEAGVTSATTAQRAAFEAAMFGDINNSELDDDILGPETEVLSGIFINNSAGTSINLINMIKTLTTELSLEKQELEKLHSMQNFMQNYTINLDFINKHMIDMNEKHLLKLSTALQKTLSENNDALLKESEDQLKEIKQQNNKVKSACSLKEKQNHEKLQELESELRELNLQIEEERGKNLVLTQSNFNGGINNDNNAKVKQNDSREEKKDTEDTLISTEELGVVEGKRTRVSKGMLFGVVAISFGLVATAVKQLPQ
What is the function of this protein?
Participates in the control of the reentry into the cell cycle following pheromone treatment.  Involved in vacuolar protein sorting.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 64, Factor arrest protein 9.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Protein: Y1398_METJA
Sequence: MKKDTLLLIILILFCIVHVYGIYVHIYGINVSLENVSQYLYNTTVYLSYENGTPCFYIGEKKEFVIIPPYIKVDRDIAPLIKKLRFKIENKSYNLIITKKNVNTNKMAIIFTSINGSREVNGNKTIIWIKDPLKLKQSEVEALYELPEKGEVIARYKDGKPAAIKINNKIYVGFKPDEDVLANLIYIHIVKKTSNPLPYILFTVFLTLASLMLTFQETLKKKFLELISALASVKVFILSRINLLDEEKVLLNDTRREIYNYILDNPGCHLRELSKNLNKPVSTLTWHLRILEKANLIKSKKFGNRLIYYPADMDMRDLPLLYLKNETQKSIFEYLLKSPAHLRKIAKDLNLNVETVRYNLKKLENLGIVKSKEEGNRIVYYINESILKFHK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MJ1398.
Protein: KAX8R_MESEU
Sequence: MSRLYAIILIALVFNVIMTIMPDMKVEAVSCEDCPEHCATKDQRAKCDNDRCVCEPK
What is the function of this protein?
Inhibits Kv1. 1/KCNA1, Kv1. 3/KCNA3 and Shaker potassium channels.
What are the official names of this protein?
Potassium channel toxin MeuTXKalpha2.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 08 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDC_SALPB
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQTQQTTQTTTTAAGSAADQGVPASGQGKMITVKTDVLDLTINTRGGDVEQALLPAYPKELGSNEPFQLLETTPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAFVLADGQNELQVPMTYTDAAGNTFTKTFVFKRGDYAVNVNYSVQNTGEKPLEVSTFGQLKQSVNLPPHRDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNVSSKGGWVAMLQQYFATAWIPRNDGTNNFYTANLGNGIVAIGYKAQPVLVQPGQTGAMTSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL17_YERPG
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDNVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRAASQAEVVAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DTD_STRT1
Sequence: MKIVIQRVQSASVAIEDSTVGTIKQGLLLLVGVGPEDTKEDLDYAVRKIINMRIFSDEDGKMNLSVKDIGGQILSISQFTLFADTKKGNRPAFTGAAKPDMASQFYDDFNQSLSSYVPVERGRFGADMQVSLVNDGPVTVILDTKNR
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_XANC5
Sequence: MPEYRSKTSTHGRNMAGARALWRATGMRDGDFHKPIIAIANSFTQFVPGHVHLKDLGQLVAREIERVGGVAKEFDTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPTVFVSGGPMEAGKTKLAEHKLDLIDAMVIAADDSASDEKVAEFERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTVVATHADREQLFLRAGRVAVELCHRWYGGEDPTALPRGIATFEAFENAMTLDIAMGGSTNTILHLLAAAQEGEVAFGMHDIDRLSKRVPQLCKVAPNTPKYHIEDVHRAGGIMAILGELARGGLLHTNAATVHARTLAEAIAQWDVTQTDDETVHTFYKAGPAGIPTQIAFSQATRWDSLDTDRSEGCIRDIAHAFSQEGGLAVLYGNIARDGCVVKTAGVDESIHVFEGTARVFESQDAAVKGILADEVVAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKQCALLTDGRFSGGTSGLSIGHASPEAAAGGAIGLVRDGDRILIDIPKRSINLLISDEELALRRAEQDAKGWKPVEVRPRKVTTALKAYALLATSADKGAVRDKALLDG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: BKRB1_PIG
Sequence: MASQTLVVFQASNQSQLPPPNATLCDGAQEAWHLLHKVLPTCVVAICSGGLLGNLFVLSVFLVPRRRLNAAEIYLAHLAASDLVFALGLPFWAETIRNGFHWPFGAPLCRVVNGVIKANLFISIFLVVAISRDRYRALVHPVASWRRRRRRHWAQATCVLIWTAGGLLSIPTFLLRSVQVVPELNVSACVLPFPHEAWAFVRTVELNVLGFLLPLAAILFFNYHILAALRGREQLSRTRCGGPRDGKTTALILTLVAVFLLCWTPYHVCAFLEFLLHVRAIRGCFWEDFTDLGLQYTNFFAFINSCLNPVIYVFWGQLFRTKIWELYHRCLPRKLTAVSSSRRKEIFQIFWRN
What is the function of this protein?
This is a receptor for bradykinin.  Could be a factor in chronic pain and inflammation.
What are the official names of this protein?
B1 bradykinin receptor, B1R, BK-1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNP_TRIL1
Sequence: MTFNEKCVEAQVGNMNVKISTGKMAKQASGAVVISSGDTMVLVTVVGTKEAKPGQDFFPLTVNYTEKTYAGGKIPGSFFKREGRPSEDETLICRLIDRPIRPLFPESYLCDTQVMATVISAEEDHDPAILSMIGASAALMISDIPFEGPIAGVKVGRVDGKLIANPSAEQLKLSDLEIVVAAGKDAIFMVEGEADFVSEEDLLEAVFFAKDAVQGILAAQEELARQVGVAKREVAPLVVDEALKAKVKALAFDRIAQAFKIKAKQERYAAVAQIKEEVVAALAEEFEGRDKEIKGFIGDIEYDRMRHDVLETGIRIDGRDTKTVRPIAIEAGLLPRAHGSTLFTRGETQVLAAATLGTSQDEQRMDSLYGEYRKKFMLHYNFPPFSVGETSFRLAPGRREIGHGMLAERAISAILPNHDDFPYTIRIVAETLESNGSSSMATVCGGCLSLMDAGVPVKAPVAGIAMGLIKEGEKVAILTDILGDEDHLGDMDFKVAGSADGVTALQMDIKIGGVSKEIMQQALKQAKEGRLHILGKMAQCLAAPREEMSAFAPRITTIWIKPDRIRDVIGTGGKTIRSITEATGVMIDIDSDNSGKINIASSDKAACDAAIQMIRGLTDEVEEGKLYMGTVKKIMEFGAFVEVLPGTDGLVHISELDETRVKNVTDILNEGDKVLVKCIGVDKQGKIKLSRKAALGQSLEEKD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTIP_PSESM
Sequence: MTVYAIIGGTGLTQLEGLNIRQSLPMNTPYGAPSGEIQIGDYAGREVMFLARHGHPHRLPPHQVNYRANIWALKQAGAEAILAVNAVGGIHPAMGTGHFCVPHDLVDYTSGRQHTFFADDLEEVTHIDFSYPYSEALRVRLVAALAAEGCAFSDRGVYACTQGPRLETVAEIIRLERDGCDIVGMTGMPEAALARELELEYACLALVVNPAAGKSTAVITMAEIEQALRDGMGKVKATLARVLSAS
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis.  Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
What are the official names of this protein?
Probable S-methyl-5'-thioinosine phosphorylase, 5'-methylthioinosine phosphorylase, MTI phosphorylase, MTIP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: NCPR_CANTR
Sequence: MALDKLDLYVIITLVVAIAAYFAKNQFLDQQQDTGFLNTDSGDGNSRDILQALKKNNKNTLLLFGSQTGTAEDYANKLSRELHSRFGLKTMVADFADYDFENFGDITEDILVFFIVATYGEGEPTDNADEFHTWLTEEADTLSTLKYTVFGLGNSTYEFFNAIGRKFDRLLGEKGGDRFAEYGEGDDGTGTLDEDFLAWKDNVFDSLKNDLNFEEKELKYEPNVKLTERDDLSGNDPDVSLGEPNVKYIKSEGVDLTKGPFDHTHPFLARIVKTKELFTSEDRHCVHVEFDISESNLKYTTGDHLAIWPSNSDENIKQFAKCFGLEDKLDTVIELKALDSTYSIPFPNPITYGAVIRHHLEISGPVSRQFFLSIAGFAPDEETKKSFTRIGGDKQEFASKVTRRKFNIADALLFASNNRPWSDVPFEFLIENVQHLTPRYYSISSSSLSEKQTINVTAVVEAEEEADGRPVTGVVTNLLKNIEIEQNKTGETPMVHYDLNGPRGKFSKFRLPVHVRRSNFKLPKNSTTPVILIGPGTGVAPLRGFVRERVQQVKNGVNVGKTVLFYGCRNSEQDFLYKQEWSEYASVLGENFEMFNAFSRQDPTKKVYVQDKILENSALVDELLSSGAIIYVCGDASRMARDVQAAIAKIVAKSRDIHEDKAAELVKSWKVQNRYQEDVW
What is the function of this protein?
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes.  It can also provide electron transfer to heme oxygenase and cytochrome B5.  Involved in ergosterol biosynthesis.
What are the official names of this protein?
NADPH--cytochrome P450 reductase, CPR, P450R.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Mitochondrion outer membrane; Single-pass membrane protein; Cytoplasmic side. Cell membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: GCST_THEP3
Sequence: MDNLKKTPLFDLYKKYNGKIIDFAGWALPVQFESIISEHEAVRNAAGLFDVSHMGEITVKGREAFNFLQNLITNDLSKLKDNQVFYTFMCNYNGGVVDDLLVYKYSDEHFLLVVNAANIEKDYKWMKDNKGVYEVEINNISDEISELAVQGPKAEEILQKLTYTDLSEIKFFYFKDNVKIAGIECLVSRTGYTGEDGFEIYMPNKYAVELWEKIIEVGKEYGLKPAGLGARDTLRFEAGLPLYGNELSEEITPLEAGFEFFVKFDKGNFIGKDALLKQKEEGLKRKIVGFEMIDNGIPRHGYEVRADNQKIGYVTTGYFSPTLKKNIGLALIDSKYAQLGNQIEIVIRNKPLKALIISKNFYKKNYKK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RL25_THEP1
Sequence: MVSLEARVREVKGKREARRLRRNGEVPAVVYGPATEPIPVKIKRSVLEKVFHTISEATPIQLIIKDDQGNTVSEKTVFLKMIQRDKVSETVVHLDFYEPTKGHRMRINVPLKVVGKPVGVEKGGFLEVFHEEIPVETDPDNVPQEIEVDVSSLDLGDVIYARDLKLPEGVKCLLGDEEVVVSVLVPKEVVIEETTEAEETAEPEVIRRKEEEEE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: MURD_PELPB
Sequence: MDLKGKRVSVIGAGKSGIAAAQLLARKGATVFVSELGTMGAEEMQHLREMQIPFEEAGHSPAVYEADFCVISPGIPPHAEVVTTLQARNIPLYSEIELASRFCKARIVGITGTDGKTTTSTLVHALCEEDGLRNGYRAYSVGNIGVPFSSMVLDMKAGDIAVVELSSYQLERSPTLKPEVAVIMNITPDHLDRYAGELQGYAAAKFRIYANQGAGDTLIYNEDDALLREHFACRDQFPFNIMSFGMEPACKGVPDIRTFFLEGDTLVAHTPDGDEPVLVTSDFLKKSFRGRHNISNVLAAVAVAGALGIQREVVCQVIREFRGVEHRQEFVMTINGVDWVNDSKATNMNALRQALEALPATAVLIAGGRDKGNDYAAITRLVEKKVSLLIALGESQDKIVSAFKDVVAVKAAGSLEDAVLLARDAASSGQTVLFSPGCASFDMFKNFEDRGMQFKQCVHQLSSW
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.