PharMolix/UniProtQA huggingface dataset:
Protein: ISPF_PETMO
Sequence: MLKIGFGYDVHPFAENRRLILGGVVINHPKGYGLLGHSDGDVFFHALIDSLLGMCGLGSIGEYFPESKEFENISSSILLEKTIDLINKRYIVKINNIDVVIISKSVNISSITGQIKNNTSCILNLEVSRINLKGKSGNGLGVGGNDQGIEVYCTILGEIDEI
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RNAS1_MYOCO
Sequence: SESSAKKFERQHMDSRGSPSTNPNYCNEMMKSRNMTQGRCKPVNTFVHEPLADVQAVCFQKNVLCKNGQTNCYQSNSNMHITDCRVTSNSDYPNCSYRTSQEEKSIVVACEGNPYVPVHFDASVAASA
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACTB_XENLA
Sequence: MEDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells.  Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction.  In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
What are the official names of this protein?
Actin, cytoplasmic 1, Beta-actin, Cytoplasmic beta-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus.
Protein: PAND_LISMH
Sequence: MFRTMMNGKIHRATVTEANLNYVGSITIDSAILEAVDMLPNEKVQIVNNNNGARIETYIIPGEPGSGVICLNGAAARHVQVGDVVIIMSYGMFTAEEAKTHEPKIVVLDEKNHIEMILPEEKAHTTL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYW31_THEKO
Sequence: MFLYTENFDEQKEKAMEGLRKALEEDKVDHDIIPLLEKINALQNYFTTSSCSGRISVMEMPHFGDKVNSVWLGKWHREVRLEEVLEAVGKHRSGQLWFLVRSPILHVGARTLEDAVRLLNLAIGLGFKYSNIKSVSHKKLVVEIRSTERMDVPLGENGELWVDEAYIEKIVNLANAQVRRFKGKLKRLEEEIEKLQED
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway.  Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.
What are the official names of this protein?
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 1, tRNA wyosine derivatives biosynthesis protein Taw3 1.
What is the protein family that this protein belongs to?
Belongs to the TYW3 family.
Protein: NST1_ASPNC
Sequence: MSDPASTSIPAHATNGEAHAPNDHHHAQLPLSDSKPVSVNRKKQKRRQKQAARLAAERQFGNGHISADMSEQNGLSPTAPASHVSDDHDLDERANGETYYEEIHDATHDLDDHPPNLSNGQPGQQNATARKSKKKKGKKNRAGSQTMGDESSTPLSTPSVSMSQHLPPPLPSHLPHTLLKTSKDRSIWNTSTQEERENIKTFWLELGEEERRQLVKVEKDAVLKKMKEQQKHSCSCTVCGRKRTAIEEELEVLYDAYYEELEQYANNNQGSFEKGPPMVPPPRLYHPPLRSPGQHTRTQGQFHPSRGRIHELPEDDEDLEEDYDEDDEDDEPYSDDEYEDEETRAARADFFAFGNSLTVKGRRQIMLLSFIFPKPVTNLIFTLADGILTVADDLLKNDGKHFIDMMEQLAERRMQREEDTQYGIAAAHQSLHGGHNHGPLDDDDYDEEEDEDYDSQEDEDYEEDEMVSSGNWPGGDAVQADSFLQDAMTEEQRMEEGRRMFQIFAARMFEQRVLTAYREKVAEQRQQKLIEELMEEQTRNEQRNAKKAREAQKRKDKKKLQKQAKEEEKARREAEKAAEEAAAKAEQEKKLEEQRRKREEQKKKREAERKAQEAERLRKEAEKQKRLREERERQAEIERKQREQKELEKKRREEARQNELREKKTKDERERKLREAAPKTDYEGQEKRDPQAKRVSHTGPVPIPASLQHAQALPAYLQSPHYQIATPIVPKAPTPARPRQPSQQGSHTSSPRSQPASTEPSQVSISPRSMAPSQSSGASSVTSKQGHGQPPLLHHPQPSTPLSPLGALNRSHPPGFSPSNPPGLGLVARPPIGHELPSYPPHSGPLMNQLRGFPAPNGLPVLPGMNGTRPMPPGRGFPLDPGHGLAFHQQPIANAFAAQPSGLSHAHSRQPSSSFERSPLDAHAFPISRPSPIKRPSSTQQDQNNRSAQRDVDDLSAHLGSSALLDDSDVPFTSNLSQSLPGATAPGTLPGPTRASFAGTSLFADPLAAKHSGFPIGPSVGNTWSTQIPFGTSPFPSAPTWGTGPGSGWSNNAFAPGGHHRAHTSRPVTIRLLVIQACKQLNMMSPSKGASGYHDVKVVLRQVDQLRPVNEPPISLKEMLDICDTEGNSQNGGGSFSIRSDETGECVKFEPDTNSASSGHRGSIVPGEIGSPVPSSSLPAFGGIGSSTPSVLRQFSSPTGF
What is the function of this protein?
May act as a negative regulator of salt tolerance.
What are the official names of this protein?
Stress response protein nst1.
What is the protein family that this protein belongs to?
Belongs to the NST1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_STRP4
Sequence: MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAGDNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGMVTEIEA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_COPPD
Sequence: MKVLAQNRRARHDYQILETYEAGIVLSGDEVKSAKEGNVQLRDAFVRVENGEAWLYNMHIAPYEKTGEPFRGDSKRKRKLLLHKREINKILGYLTQKGLTAIPLSMYVNDRGFIKVSIGVAKGKKMVDKRQTIKERDIERELRREGKIRY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GSA_HISS2
Sequence: MTTSATLFYRAQQVIPGGVNSPVRAFKGVGGTPVFIEKANGAYIFDIEGKQYIDYVGSWGPMILGHNHPSILSAVLKIAENGLSFGTPTPLEIELAELICQLVPSIEMVRMVNSGTEATMSAIRLARGYTKRDKILKFEGCYHGHSDSLLVKAGSGSLTLGQPSSPGVPEDFAKHTITCEYNNLQSVKNAFEQYPDQIACVIVEPVAGNMNCILPKQDFLQGLRQLCNEYGSLFIIDEVMTGFRVALGGAQSYYEVTPDLTTLGKVIGGGMPVGAFGGKKEIMQYIAPTGPVYQAGTLSGNPIAMSAGIACLNELKKEGNEQRLAMLTKKLALGLKNLANQHNIPLVVNYVGGMFGIFFTTQNEVTSYQQAIQCDIERFNLFFHKMLEQGVYLAPSAFEAGFMSLAHTDADIDRTLQAADIAFASLRSSSFS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDX52_HUMAN
Sequence: MDVHDLFRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLDFFGNKKSVPGVCGASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAVRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQNSKKKVALEDKS
What is the function of this protein?
Required for efficient ribosome biogenesis (By similarity).  May control cell cycle progression by regulating translation of mRNAs that contain a terminal oligo pyrimidine (TOP) motif in their 5' UTRs, such as GTPBP4 (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX52, ATP-dependent RNA helicase ROK1-like, DEAD box protein 52.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ARGLB_DANRE
Sequence: MGRSRSRSSSRSKHSKTSKHSKKRSRSRSRSRDRERKRRSKSRESKRNRRRESRSRSRSNTATSRRDRERAASPPERIDIFGRALSKRSAVDEKQKKEEEEKKVEMERQRRIRQQEIEERLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRHAELAAQKAREEEEKSKREELEKILVDNNRKIADAQAKLAEDQLRIVEEQRKIHEERMKLEQERQKQQKEEQKMILGKGKSRPKLSFSLKASE
What are the official names of this protein?
Arginine and glutamate-rich protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the UPF0430 family.
Protein: COPT2_HUMAN
Sequence: MAMHFIFSDTAVLLFDFWSVHSPAGMALSVLVLLLLAVLYEGIKVGKAKLLNQVLVNLPTSISQQTIAETDGDSAGSDSFPVGRTHHRWYLCHFGQSLIHVIQVVIGYFIMLAVMSYNTWIFLGVVLGSAVGYYLAYPLLSTA
What is the function of this protein?
Does not function as a copper(1+) importer in vivo (By similarity).  However, in vitro functions as low-affinity copper(1+) importer (PubMed:17944601, PubMed:17617060).  Regulator of SLC31A1 which facilitates the cleavage of the SLC31A1 ecto-domain or which stabilizes the truncated form of SLC31A1 (Truncated CTR1 form), thereby drives the SLC31A1 truncated form-dependent endosomal copper export and modulates the copper and cisplatin accumulation via SLC31A1 (By similarity).
What are the official names of this protein?
Protein SLC31A2, Copper transporter 2, hCTR2, Solute carrier family 31 member 2.
What is the protein family that this protein belongs to?
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLCT_STAAE
Sequence: MGEYIVTKTLNNNVVVCTNNDQEVILIGKGIGFNKKEGMALNDQTITIEKIYKLESEQQKAHYKSLVEIADDNVLQVIIDSLNFISNTAMNVDSKQLVVSLTDHIIFAYKRLKQNQVISNPFVMETMQLYSDAYHIAKQVIDQLNAALDVHFPEDEIGFIALHIASNTEDLSMHEMTLINNVIKKGIDIIESDLVTTVDKESLQYQRFIRHVQFLIRRLRRKEYIHAQDDFVSMIKNHYPICYNTAYKILTMIQKQFDVNISESEIIYLTLHIHHFEERINQS
What are the official names of this protein?
Protein GlcT.
What is the protein family that this protein belongs to?
Belongs to the transcriptional antiterminator BglG family. GlcT subfamily.
Protein: CPSF4_HUMAN
Sequence: MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPAKQSNNPPLQRSSSLIQLTSQNSSPNQQRTPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ
What is the function of this protein?
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.  CPSF4 binds RNA polymers with a preference for poly(U).
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 4, Cleavage and polyadenylation specificity factor 30 kDa subunit, CPSF 30 kDa subunit, NS1 effector domain-binding protein 1, Neb-1, No arches homolog.
What is the protein family that this protein belongs to?
Belongs to the CPSF4/YTH1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: P2C15_ORYSJ
Sequence: MSTRSKSVPVPAGGGAATVPLAVLLRREVVSEKTAAERPELQVGLFSQAKKGEDYTFLKPDCERLPGVPSSSFSAFGLFDGHNGNGAAIYTKENLLSNILTAIPADLNREDWLAALPRAMVAAFVKTDKDFQTKARSSGTTVTFVIIDGLFITVASVGDSRCVLEAEGSIYHLSADHRFDASKEEVDRVTESGGDVGRLNVVGGAEIGPLRCWPGGLCLSRSIGDQDVGQFIVPVPYVKQVKLSTAGGRLIISSDGVWDVLTAEVAFNCSRTLPPEAAAEQIVKEAVQQKGLRDDTTCIVVDILPDKANLTMPHTKKQPGMGVFKNMFRKKTPSDSSSHTDREYMDPDIVEEIFEDGCAFLSKRLDSEYPVRNMFKLFICAICQVELKPSQGISVHEDSSQPGNLRRWDGPFLCQGCQEKKEAMEGKRRSRDSSSRNSGSSE
What are the official names of this protein?
Probable protein phosphatase 2C 15, OsPP2C15.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: TDCA_ECO57
Sequence: MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
What is the function of this protein?
Transcriptional activator for the tdcABCDE operon.
What are the official names of this protein?
HTH-type transcriptional regulator TdcA, Tdc operon transcriptional activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: YFAS1_KLULA
Sequence: MRLNILSTLLLLGAIDKVVARRVLNLDSLDVSDSDSKNEKREPKRLPLDIEGIMAGHDEAMDKRDARRIGLNVDGLSDSELRLRKRDLRRPQFVLDITQGKVEERVNLDSRLAILQDISLFSEYGRDVTEVVAQWEDRSQELIVIAPTNDAISKLSMKPWQFPNNIDAMEQSNAEPKQIDDAIKENVAHFVKSHIVAHSDDFDLESDEIWLHSEADTSEKGDIVLKRQNNEYFVASASNMDFKLVKTVDVAANGVILIIDSSLITP
What are the official names of this protein?
FAS1 domain-containing protein KLLA0E16841g.
What are the subcellular locations of this protein?
Vacuole.
Protein: RLMF_SALNS
Sequence: MSAQKPGLHPRNRHQHRYDLAALCQTTPELTSFLIRTPAGEQSVDFANPQAVKALNKALLAHFYAVTHWDIPPGFLCPPVPGRADYIHHLADLLGETTGSIPAQATILDVGVGANCIYPLIGVHEYGWRFTGSEVSDAAMSSAQAIIQANTGLSRAIRLRRQKDPAAIFTGIIHKNEFYDATLCNPPFHDSAAAARAGSERKRRNLGQNKDDALNFGGQQQELWCEGGEVAFIKKMIAESQSFRRQVLWFTTLVSRGENLPPLYRALTEAGAVKVVKKEMAQGQKQSRFIAWTFMDDDQRRRFITRKR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_CHLSY
Sequence: MANTKSAKKRIRSDARKHLRNQSYRSRVKTMIKKAELALANGVVDEAALRMAYSTLDKAAVKGIIHKNNAARRKSRLAQKAKKVALAAQAGSAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: TRPF_XANOM
Sequence: MNRSLYRTRIKFCGMTRAGDIRLAGELGVDAVGFIFAHGSPRRVAPAEARAMRQATAPMVDVVALFRNNSKEEVREVVRTVRPTLLQFHGEEEDAFCRSFNLPYLKAVPMGSTGVNGEDANARTLQLSYPNTAGFLFDSHAPGAGGGTGKTFDWSRLPTGLHRPFLLAGGINAGNVFDAIVATLPWGVDVSSGVELAPGIKDGHKMRKFVEEVRRADCHEMS
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: EFTS_CYACA
Sequence: MSNKSSKTSKVSIDLIKQLREKTGVSIKDCKEALRKHDGDIAKALREIQEQGSAIAQEKHNRITVHGRIASYIHINNRMGSLVEINCETDSAANSEEFAKLCQHIAMQIVACPEIKYVKFEDIPEEIKNHYIEVESQSKDLQDKPAQSKNKIIRGRIDKKLRRMCLLDQANIKDDKVTVNDLIKEKINKFKENIQINRFARFTIGEKI
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, chloroplastic, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS1_CYTH3
Sequence: MSTVLRLAIQKSGRLSEESIKLIKECGIEFSSGGGTLKSVAYNFPLEVLFLRDDDIPGYVADGVADIGIVGENVAVETRKKMDTVRQLGFSKCRLSIGVPKAMEFTGKESLNGMRIATSYPNILSDYLFENNIKASIHEISGSVEIAPGIGLADAICDIVSSGSTLISNGLKETEVVFRSEAILAACPQLSAEKKAILDELMFRISAVKNAEKTKYIMLNVPDHAIQTVTALLPGVKSPTVMPLAEKGWSSLHSVVKESDFWEILSKLKEAGAEGILVLPIEKIVK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_SHISS
Sequence: MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerC specifically exchanges the top DNA strands.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 2AAB_HUMAN
Sequence: MAGASELGTGPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLALA
What is the function of this protein?
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform, PP2A subunit A isoform PR65-beta, PP2A subunit A isoform R1-beta.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit A family.
Protein: PA24E_MOUSE
Sequence: MQSIPHSDEADVAGMTHASEGHHGLGTSMLVPKNPQGEEDSKLGRNCSGFEDAQDPQTAVPSSPLLSMASCSSQEGSSPCHLLTVRIIGMKNVRQADILSQTDCFVTLWLPTASQKKLKTRTISNCLHPEWDESFTFQIQTQVKNVLELSVCDEDTLTQNDHLLTVLYDLSKLCLRNKTHVKFPLNPEGMEELEVEFLLEENFSSSETLITNGVLVSRQVSCLEVHAESRRPRKRKKNKDLLVMVTDSFENTQRVPPCQEPCYPNSACFHYPKYSQPQLYAEAPKSHCNFRLCCCGTHRNDPVCQPLNCLSDGQVTTLPVGENYELHMKSSPCSDTLDVRLGFSLCQEEVEFVQKRKMVVAKTLSQMLQLEEGLHEDEVPIIAIMATGGGTRSMVSLYGHLLGLQKLNFLDASTYITGLSGATWTMATLYSDPEWSSKNLETVVFEARRHVVKDKMPALFPDQLYKWREDLQKHSQEGYKTTFTDFWGKLIEYSLGDKKNECKLSDQRAALCRGQNPLPIYLTINVKDDVSNQDFREWFEFSPYEVGMQKYGAFIPSELFGSEFFMGRLMKRIPEPEMCYMLGLWSSIFSLNLLDAWNLSHTSEEFFYRWTRERLHDIEDDPILPEIPRCDDNPLETTVVIPTTWLSNTFREILTRRPFVSEFHNFLYGMQLHTDYLQNRQFSMWKDTVLDTFPNQLTQFAKHLNLLDTAFFVNSSYAPLLRPERKVDLIIHLNYCAGSQTKPLKQTCEYCTEQKIPFPSFSILEDDNSLKECYVMENPQEPDAPIVAYFPLISDTFQKYKAPGVERSPDELELGQLNIYGPKSPYATKELTYTEAAFDKLVKLSEYNILNNRDKLIQALRLAMEKKRMRSQCPS
What is the function of this protein?
Calcium-dependent N-acyltransferase involved in the biosynthesis of N-acyl ethanolamines (NAEs) in the brain (PubMed:27399000).  Transfers the sn-1 fatty acyl chain of phosphatidylcholine (fatty acyl donor) to the amine group of phosphatidylethanolamine (fatty acyl acceptor) to generate N-acyl phosphatidylethanolamine (NAPE).  Similarly can use plasmenylethanolamine as a fatty acyl acceptor to form N-acyl plasmenylethanolamine (N-Acyl-PlsEt).  Both NAPE and N-Acyl-PlsEt can serve as precursors of bioactive NAEs like N-arachidonoyl phosphatidylethanolamine also called anandamide (PubMed:27399000, PubMed:29447909).  Has weak phospholipase A2 and lysophospholipase activities (PubMed:27399000, PubMed:15866882).  Regulates intracellular membrane trafficking that requires modulation of membrane curvature as it occurs by enrichment in lysophospholipids.  Promotes tubule formation involved in clathrin-independent endocytotic trafficking and cargo recycling (PubMed:24413173).
What are the official names of this protein?
Cytosolic phospholipase A2 epsilon, cPLA2-epsilon, Calcium-dependent N-acyltransferase, Phospholipase A2 group IVE.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Targeted to clathrin-independent endocytotic vesicles through binding to phosphoinositides, especially phosphatidylinositol 4,5-bisphosphates.
Protein: PHEB_RHOVL
Sequence: MLDAFSRVVVNSDTKAAYVGGSDLQALKKFIADGNKRLDSVNAIVSNASCVVSDAVSGMICENPGLITPGGNCYTNRRMAACLRDGEIIIRYVSYALLSGDPSVLEDRCLNGLKETYIALGVPTNSNARAVDIMKASVVALINNTATLRKMPTPSGDCSALAAEAGSYFDRVNSALS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
B-phycoerythrin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the periphery of the phycobilisome rod.