PharMolix/UniProtQA huggingface dataset:
Protein: PLSY_TOLAT
Sequence: MLALTFAMSGIAYLLGSVSNAVLISRLCDLPDPREYGSHNPGATNVLRSGNRLAALIVFLLDMLKGTIPVYLAWYLGIPPLYLGFIGIAACLGHMYPLYFHFRGGKGVATALGALLPLGLDMGSFMIVTWLIVLLFTGYSSLAAIGAALLAPLYTYCLKPEYTLPVAMLCCLIILRHHENISRLLQGHEPQVWSRHPLKRHRR
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y382_RICPR
Sequence: MHSTNKSHNNSLANAWLKLGIISLGLGGLYSIILVVLRTPQLSSFFLNQRIFKSALIIHVNLSILIWLLSITASVWGNETSLRLVKRRGIFIPFGLLREIVTFYTFDRNDVLYIYPKLAFFATLLIAISPLAGYNTVTNNYIPMLANIVFILGLSLFGVTLLLYAINILYLFDWMKLNNLVNVTVFSTIIMFILSFVCFGWSYKSLQKIIQIIPIEIEFYYELLFWSGGHLLQFIYTQILIFIWVSLLRTITVRELKFQTFYLFILYLNFVFSILILFGHISYDIIDIAFKEFYTDHMKYLGGIAPILCLVGMVVELVLMSYRDKLVLLIYRLSTKSSKIKKDCITLSNHRTHSIIKTILLCSITLFLLGGLIAININDINLVIPAHYHGSIVGISIACMGYSYQTIIPLMDHDIHKTTKQYLITLSINWIKFAIYLLTFGQILHILGLAFSGIYGVMRKDPNSIVPMSSKLLMGMMGIGGLIAIVGGLMFVYICGKTMFFLKGMKLEYE
What are the official names of this protein?
Uncharacterized protein RP382.
What is the protein family that this protein belongs to?
To A.aeolicus AQ_155.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRXC_CURIN
Sequence: MGSVTPIPLPKIDEPEEYNTNYILFWNHVGLELNRVTHTVGGPLTGPPLSARALGMLHLAIHDAYFSICPPTDFTTFLSPDTENAAYRLPSPNGANDARQAVAGAALKMLSSLYMKPVEQPNPNPGANISDNAYAQLGLVLDRSVLEAPGGVDRESASFMFGEDVADVFFALLNDPRGASQEGYHPTPGRYKFDDEPTHPVVLIPVDPNNPNGPKMPFRQYHAPFYGKTTKRFATQSEHFLADPPGLRSNADETAEYDDAVRVAIAMGGAQALNSTKRSPWQTAQGLYWAYDGSNLIGTPPRFYNQIVRRIAVTYKKEEDLANSEVNNADFARLFALVDVACTDAGIFSWKEKWEFEFWRPLSGVRDDGRPDHGDPFWLTLGAPATNTNDIPFKPPFPAYPSGHATFGGAVFQMVRRYYNGRVGTWKDDEPDNIAIDMMISEELNGVNRDLRQPYDPTAPIEDQPGIVRTRIVRHFDSAWELMFENAISRIFLGVHWRFDAAAARDILIPTTTKDVYAVDNNGATVFQNVEDIRYTTRGTREDPEGLFPIGGVPLGIEIADEIFNNGLKPTPPEIQPMPQETPVQKPVGQQPVKGMWEEEQAPVVKEAP
What is the function of this protein?
Catalyzes the oxidation of chloride in the presence of hydrogen peroxide to hypochlorous acid (ClOH), which in turn can react with a nucleophilic acceptor (RH), to form a chlorinated compound.
What are the official names of this protein?
Vanadium chloroperoxidase, Vanadium chloride peroxidase, VCPO.
What is the protein family that this protein belongs to?
Belongs to the vanadium-dependent haloperoxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: COR1B_MOUSE
Sequence: MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEDWVSGQDANPILISLREAYVPSKQRDLKVSRRNVLSDSRPASYSRSGASTATAVTDVPSGNLAGAGEAGKLEEVMQELRALRMLVKEQGERISRLEEQLGRMENGDT
What is the function of this protein?
Regulates leading edge dynamics and cell motility in fibroblasts.  May be involved in cytokinesis and signal transduction (By similarity).
What are the official names of this protein?
Coronin-1B, Coronin-2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Note=Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers.
Protein: RL4_CHLPD
Sequence: MELKVLNTSGTETGEVVTLNEEIFGVEVSEHAMYLDVKSILANKRQGTHKAKTRAQVRGGGRKPYRQKGTGNARQGSTRSPLMIGGGTIFGPQPRSYDQKVNKKVKLLARRSALSAKAKAGKILVIEDFRLDAIKTKPVAEILKNLGLEQKKILMLTPEYDMIIARSGRNIPVLNIMTADKVSTYDILNSSAILFQKTALTKIEDTLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y2013_STAA8
Sequence: MTKKVAIILANEFEDIEYSSPKEALENAGFNTVVIGDTANSEVVGKHGEKVTVDVGIAEAKPEDYDALLIPGGFSPDHLRGDTEGRYGTFAKYFTKNDVPTFAICHGPQILIDTDDLKGRTLTAVLNVRKDLSNAGAHVVDESVVVDNNIVTSRVPDDLDDFNREIVKQLQ
What are the official names of this protein?
Uncharacterized protein SAOUHSC_02013, ORF1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
Protein: EFTU_LYSSC
Sequence: MAKEKFDRSKTHANIGTIGHVDHGKTTLTAAIATVLSKKMGGTAKSYADIDNAPEEKERGITINTSHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRQVGVPYLVVFMNKCDMVDDEELLELVEMEIRDLLSEYDFPGDDIPVIKGSALKALEGEPEWEEKIVELMDAVDSYIPTPERQTDKPFMMPVEDVFSITGRGTVATGRVERGQVKVGDVVEIIGIAEEAKSTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREEIQRGQVLAKPGSITPHTNFKAEVYVLSKEEGGRHTPFFSNYRPQFYFRTTDVTGICNLPEGVEMVMPGDNIEMTVELIAPIALEEGTKFSIREGGRTVGAGVVASIQK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FM25C_HUMAN
Sequence: MLGGLGKLAAEGLAHRTEKATEGAIHAVEEVVKEVVGHAKETGEKAIAEAIKKAQESGDKKMKEITETVTNTVTNAITHAAESLDKLGQ
What are the official names of this protein?
Protein FAM25C.
What is the protein family that this protein belongs to?
Belongs to the FAM25 family.
Protein: RMP_BOVIN
Sequence: MEAPPDPRPHASAAAPLRAPEVARLREEQEKVVTNCQEKIQHWKKVDNDYNALQERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKTDFEFKAKHRIAHKPHSKPKTSDIFEAEFANDLKSKDLLADKELWDRLEELERQEELLGEIDIDSKPDTVIANGEDVSSEEEKEDQNINVNMMHQVTDSLALSSCYNSLTNSELFNGQVNSPLNYSVNGSSSYHSNEDDGDNNDDGGDSENDHDTLGVEDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSSGSGHSPQELPMIRTPADIYRVFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAADFDDRRGVLRSISCEEATCSDASESILEEEQENHQKKLLPLSVTPEAFSGTVIEKEFLSPSLTPHPAMAHPVLPTIPERKEVLSEVSEGTTKRVSKFKAARLQQKN
What is the function of this protein?
Plays a central role in maintaining S6K1 signaling and BAD phosphorylation under normal growth conditions thereby protecting cells from potential deleterious effects of sustained S6K1 signaling.  The URI1-PPP1CC complex acts as a central component of a negative feedback mechanism that counteracts excessive S6K1 survival signaling to BAD in response to growth factors.  Mediates inhibition of PPP1CC phosphatase activity in mitochondria.  Coordinates the regulation of nutrient-sensitive gene expression availability in a mTOR-dependent manner.  Seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs and proteins with roles in transcription and ubiquitination (By similarity).
What are the official names of this protein?
Unconventional prefoldin RPB5 interactor, Protein phosphatase 1 regulatory subunit 19, RNA polymerase II subunit 5-mediating protein, RPB5-mediating protein.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase II subunit 5-mediating protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion. Cell projection, dendrite. Note=Colocalizes with PFDN2, PFDN4, PPP1CC, RPS6KB1 and STAP1 in mitochondrion.
Protein: NCF1_MOUSE
Sequence: MGDTFIRHIALLGFEKRFIPSQHYVYMFLVKWQDLSEKVVYRKFTEIYEFHKMLKEMFPIEAGEIHTENRVIPHLPAPRWFDGQRAAESRQGTLTEYFNGLMGLPVKISRCPHLLDFFKVRPDDLKLPTDSQAKKPETYLVPKDGKNNVADITGPIILQTYRAIADYEKSSGTEMTVATGDVVDVVEKSESGWWFCQMKTKRGWVPASYLEPLDSPDEAEDPDPNYAGEPYVTIKAYAAVEEDEMSLSEGEAIEVIHKLLDGWWVVRKGDITGYFPSMYLQKAGEEITQAQRQIRGRGAPPRRSTIRNAQSIHQRSRKRLSQDTYRRNSVRFLQQRRRPGRPGPLSTDGTKDNPSTPRVKPQPAVPPRPSSDLILHRCTESTKRKLTSAV
What is the function of this protein?
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
What are the official names of this protein?
Neutrophil cytosol factor 1, NCF-1, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, p47-phox.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS11_BURPS
Sequence: MAKASNTAAQRVRKKVKKNVAEGVVHVHASFNNTIITITDRQGNALAWATSGGQGFKGSRKSTPFAAQVAAESAGRVAMEYGVKNLEVRIKGPGPGRESAVRALHGLGIKITAISDVTPIPHNGCRPPKRRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RS17_XYLFA
Sequence: MMNDHNERKPLRTIKGRVISNKMQKTVTVLVERQIKHALYGKYIKRSTKLHAHDADDLCNEGDVVLMTEVAPISKTKNWRVVEIVARSD
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: HLDE_SALPB
Sequence: MKVNLPAFERAGVMVVGDVMLDRYWYGPTCRISPEAPVPVVKVNTVEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKTLAEVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALGSIGALVLSDYAKGALTSVQTMISLARQAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVAGKCKSEDELVERGMKLIADYDLSALLVTRSEQGMTLLQPNKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNTLEEACYFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELRQAVASARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGESRPVNPLEQRMIVLGALESVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSEEVWANGGEVMVLNFEDGCSTTNIIKKIQTESEK
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: PP121_ARATH
Sequence: MNCLANESLNSLKISPFSTSRLLSSVTNFRNQLSFSSKDSSSSSAPFNPFRFFNDQSNSRLCNLRTTKILQAHLLRRYLLPFDVFLTKSLLSWYSNSGSMADAAKLFDTIPQPDVVSCNIMISGYKQHRLFEESLRFFSKMHFLGFEANEISYGSVISACSALQAPLFSELVCCHTIKMGYFFYEVVESALIDVFSKNLRFEDAYKVFRDSLSANVYCWNTIIAGALRNQNYGAVFDLFHEMCVGFQKPDSYTYSSVLAACASLEKLRFGKVVQARVIKCGAEDVFVCTAIVDLYAKCGHMAEAMEVFSRIPNPSVVSWTVMLSGYTKSNDAFSALEIFKEMRHSGVEINNCTVTSVISACGRPSMVCEASQVHAWVFKSGFYLDSSVAAALISMYSKSGDIDLSEQVFEDLDDIQRQNIVNVMITSFSQSKKPGKAIRLFTRMLQEGLRTDEFSVCSLLSVLDCLNLGKQVHGYTLKSGLVLDLTVGSSLFTLYSKCGSLEESYKLFQGIPFKDNACWASMISGFNEYGYLREAIGLFSEMLDDGTSPDESTLAAVLTVCSSHPSLPRGKEIHGYTLRAGIDKGMDLGSALVNMYSKCGSLKLARQVYDRLPELDPVSCSSLISGYSQHGLIQDGFLLFRDMVMSGFTMDSFAISSILKAAALSDESSLGAQVHAYITKIGLCTEPSVGSSLLTMYSKFGSIDDCCKAFSQINGPDLIAWTALIASYAQHGKANEALQVYNLMKEKGFKPDKVTFVGVLSACSHGGLVEESYFHLNSMVKDYGIEPENRHYVCMVDALGRSGRLREAESFINNMHIKPDALVWGTLLAACKIHGEVELGKVAAKKAIELEPSDAGAYISLSNILAEVGEWDEVEETRKLMKGTGVQKEPGWSSV
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g74600, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HSLV_CHLP8
Sequence: MGQQKPQIRSTTVLGVLRDGKAALGSDGQMTLGNTVMKHSTRKIRSLYQGKFVTGFAGATADALTLLERFEAKLEAYSGRLDRAAVELAKDWRTDKYLRRLEAMLAVVSSDKALIISGTGDVIEPEDGIVAIGSGSMYALAAARALMKHTTLSAEEIVRESLQTAAEICIYTNDHIAIETL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1B_THEPD
Sequence: MSKVAVLLRVLPDDAETKPEELYKKIAAALPEKYQVAQYQAEPIAFGLEALRMVILMPEETEGGTEELETIIQSVQGVSQVDVLNVTRFSG
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: Y1584_ARCFU
Sequence: MVRRGAMVLLTMLILYAAPSFALYGLADFMSFVYVGAIMIVAFGVYIILGRSKKPGFKEMLAVMLISALTAIFLAYFFSGSEVIVPKLKSLGLFAVVAAMLLALARVFRLEAEADFSLRFFLKWILVVAITFTILSVFMLFLRGVV
What are the official names of this protein?
Uncharacterized protein AF_1584.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YORP_TTV1K
Sequence: MSDVGYCSPPGKNNSDYLTAFHCVSREMCNIVSNIQLSDGTKVNVIKTPYMKHCSNILCRLLFEIGLNRLFPMCIEDEDLAWISAGNNIGPTKGVLFAGSLGSIYGSIAIFSGDLIVGKKYKVISRDFYIGKTIEWETTINGKGIFYVLYENGKGIWIRGYYSFPTQVRIKPGFSGSPVIEE
What are the official names of this protein?
Uncharacterized 20.2 kDa protein.
Protein: PPK4_PSEFO
Sequence: DHLPHDVYSPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Pyrokinin-4, YXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUSB_BRUC2
Sequence: MNSIPEGRPTPNLPRTANKRGVARLAAVQALYQMDVAGTGVMEVVAEYEAFRLGKEVDGTQYLDADPQWFRAIVAGVVEDQLKLDPMIHQALTEDWPLSRLDSTLRAILRAGAWELKARKDVPTAVIVSEYVDIAKAFYTEDEPKLVNAVLDRLALVIRGESRGAKPRHKS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ACDAS_XANCP
Sequence: MTDLLASTLEHLETLVSFDTRNPPRAIAAEGGIFDYLRAQLPGFQVEVIDHGDGAVSLYAVRGTPKYLFNVHLDTVPDSPHWSADPHVMRRTEDRVIGLGVCDIKGAAAALVAAANAGDGDAAFLFSSDEEANDPRCIAAFLARGLPYDAVLVAEPTMSEAVLAHRGISSVLMRFAGRAGHASGKQDPAASALHQAMRWGGKALDHVESLAHARFGGLTGLRFNIGRVDGGIKANMIAPAAELRFGFRPLPSMDVDGLLATFAGFADPAAAHFEETFRGPSLPSGDIARAEERRLAARDVADALDLPIGNAVDFWTEASLFSAGGYTALVYGPGDIAQAHTADEFVTLAQLQRYVESVNRIINGSH
What is the function of this protein?
Catalyzes the deacetylation of N-acetyl-L-citrulline to produce L-citrulline.  This is a step in an alternative arginine biosynthesis pathway (PubMed:16585758, PubMed:16511126).  Is also able to catalyze the deacetylation of N-acetylornithine in vitro, with almost equal velocity.  However, this reaction may be not relevant in vivo since Xanthomonas does not possess the canonical argF gene and cannot convert ornithine to citrulline via ArgF' (PubMed:16585758).
What are the official names of this protein?
N-acetyl-L-citrulline deacetylase, ACDase, Acetylcitrulline deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetylcitrulline deacetylase subfamily.
Protein: URGC_RUBXD
Sequence: MQKEAVRDAANLPSIRSLVRAVGFEGRSLHSINDLTNDQIYALFELARALEPFHRSSVDLLRGSVMVTLFFQPSTRTRMSFETAMHRLGGAVVTEANPLVSSSAAKEESLADTMRTISKYANVIVLRHPDDVAAREGASYSESPVINGGWGDWEHPTQALLDLYTLWRTHGGVEGAKVVVATPDMVHARTGHSMAYGLARLGAEVTLASRSDYRAPEEVIEGLRRVEGAKVREVFDLDQDGFNDLVSEMDLVYLPGCSAPKGEAAEEFKKMMDEYYVRLETLEKVRESEGRIIRVTHTLPRRPGEMDLRIDDTPHQQYFEAIAYSVAIRMALVAAIVGA
What is the function of this protein?
Catalyzes the phosphorolysis of allantoate to ureidoglycine and carbamoyl phosphate (PubMed:24093154).  Is likely involved in a purine degradation pathway (PubMed:24093154).
What are the official names of this protein?
Ureidoglycine carbamoyltransferase, UGTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
Protein: JAG1_HUMAN
Sequence: MRSPRTRGRSGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSNDTVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYSIYIACEPSPSANNEIHVAISAEDIRDDGNPIKEITDKIIDLVSKRDGNSSLIAAVAEVRVQRRPLKNRTDFLVPLLSSVLTVAWICCLVTAFYWCLRKRRKPGSHTHSASEDNTTNNVREQLNQIKNPIEKHGANTVPIKDYENKNSKMSKIRTHNSEVEEDDMDKHQQKARFAKQPAYTLVDREEKPPNGTPTKHPNWTNKQDNRDLESAQSLNRMEYIV
What is the function of this protein?
Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (PubMed:18660822, PubMed:20437614).  May be involved in cell-fate decisions during hematopoiesis (PubMed:9462510).  Seems to be involved in early and late stages of mammalian cardiovascular development.  Inhibits myoblast differentiation (By similarity).  Enhances fibroblast growth factor-induced angiogenesis (in vitro).
What are the official names of this protein?
Protein jagged-1, Jagged1, hJ1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell membrane.
Protein: GCH1_LEPBJ
Sequence: MEENIVNILKSIGEDPTREGLLNTPKRVKKAYDFLTSGYHVDITKVVNGAIFEESTEGMILVRDIEVYSLCEHHLLPFYGRAHVAYLPNKKIIGISKIPRIVDVFARRLQVQERLTEQIAYAVQEVLDPQGVAVVIKAKHLCMMMRGVEKQNSELFTSCLLGAFKENMVTRSEFLDLIRTGST
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: GUN8_ORYSJ
Sequence: MKPRSSRDGHNAAAAAALLLAALVLSGDVLPAVVAGGAPSFNYKDALTKSIMFLEAQRSGKLPPTNRIKWRGDSGMEDGKLANVDLTGGYYDAGDNVKYGLPLAFTVTTLAWTAMAFEKELKAARELENVHAAIRWGTDYFLKAATKKDHLWVQVGDPNADHQCWVRPENMPTPRTLYQINDKTPGSEIAAETAAAMTASSMVFRKDKPYSRRLLNKAKLLFQFAKTHQGTYDGECPFYCSYSGYNDELLWAATWLYLATKRQVYADFIGHEAISSSVAEFSWDLKFPGAQVLLAELNMTSSGGLQSFKSQADNFVCAVLPDTPFHQVSITPGGMIHLRDGANSQYVTSTAFLFVAYSDILRRINQPVMCGAQAVQPARLLQFAKQQIDYLLGANPRGRSYVVGFGVNPPTQPHHRGASTPVLPPGYQVNCGMSFSEWFTPDRPNPNELTGAIMGGPDGGDNFSDKRGNSSCTEPCTYINSLSIGPLAALAIRGPNLIATQ
What are the official names of this protein?
Endoglucanase 8, Endo-1,4-beta glucanase 8.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOB_PROM9
Sequence: MPNSNNQLLKEIRFDWNKEEILEILDMPLIDLMWESQTVHRKFNKYNIQLASLFSVKTGGCEENCSYCSQSIYSASEIKSHPQFQVEEVMARAKIAKNEGADRFCMGWAWREIRDGKSFNAMLEMVSGVRDLGMEACVTAGMLTEEQASRLADAGLTAYNHNLDTSPEHYKNIITTRTYQDRLDTIKRVRNAGINVCCGGIIGLGETNGDRASLLEVLSNMNPHPESVPINSLVAIEGTGLEDNQEIDSIEMIRMIATARILMPKSKIRLSAGREKLSKEAQILCFQCGANSIFYGDELLTTSNPSFQSDRKLLKEVGVSFNKDFETREKTLFSL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RS12_DEIRA
Sequence: MPTTQQLLRKGRKVLQKKSKVPALKGSPFRRGVCTVVKTTTPKKPNSALRKIARVRLSSGFEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGSLDTQGVKDRNKSRSKYGTKKPKAGAAAAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RS26_SCHCO
Sequence: MTKKRRNGGRNKSGRGHVTFVRCSNCSRCVAKDKAIKRFTVRNMVESAAIRDISDASVYPEYAIPKLYIKIAYCVSCAIHSHVVRVRSREGRRNRAPPPRVRWKDGKKVNPAVAAAEDAKAAAART
What are the official names of this protein?
40S ribosomal protein S26.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS26 family.
Protein: BGLX_ECOLI
Sequence: MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKKMTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRLKIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVDVSRDPRWGRASEGFGEDTYLTSTMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEGGKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRDQWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLIKSGKVTMAELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVARESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNAVGENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAVVGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADAILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKPNKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKREGATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYDAEPGKFNVFIGTDSARVKKGEFELL
What are the official names of this protein?
Periplasmic beta-glucosidase, Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: METK_CLOBJ
Sequence: MRKLFTSESVTEGHPDKICDQISDAVLDAILDKDPNGRVACETAVTTGMVMVMGEISTKCYVDIPKLVRETIRGIGYDRAKYGFDCETCSVITSIDEQSVDIAMGVDEALESKKGEMDKLDAVGAGDQGMMFGFATNETKEYMPMPIEMAHKLSRRLSEVRKNGTLPYLRPDGKTQVTVEYENGKPVRIDAIVISTQHGPEIYLEQIEKDIKEHVIKVIVPSELLDENTKYFINPTGRFVVGGPQGDSGLTGRKIIVDTYGGYGRHGGGAFSGKDPTKVDRSAAYAARWVAKNLVAAGVADKLEIQLAYAIGVAKPVSISVDTFGTGKMTDEEIVSIVNKVFDLRPGAIIRDLDLRRPIYKQVAAYGHFGRTDIDVPWERLDKVEEIKKHI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_PYRCJ
Sequence: MWFGRDVISARDFSREDLYELFEMAKYMEKFAKSRVDFLRGKVMATAFFEPSTRTRLSFEVAMKRLGGDVIGFGSAEGTSVEKGETLADTIRMLDAYADVIVIRHKYEGAAKLAAEVAESPVVNGGDGAYNHPTQAMLDVYTIWREFGHVDGLNVGLMGDLRNARTINSLVETLANFNVRLYFISPEFLRPRAETVDYARDKGVKMSFHTNVEEVVHELDVLYVVRIQKERFLDPLEYERVKGSYRVTLELLKNAKRGLIVLHPLPRVDEIDHRIDSTPHAKYFIQAALGVPLRMALIYLILSPP
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.