PharMolix/UniProtQA huggingface dataset:
Protein: NUOI_FRATT
Sequence: MRNITNFLKTFLLWELLKGLKVTGKHFFTRKVTVQYPDEKTPISNRFRGLHALRRYENGEERCIACKLCEVVCPALAITINSTEREDGTRRTSSYEMDLFKCIFCGYCEESCPVDSIVETNILEYHFEERGENIMTKAKLLAIGDKYEAQIAADRLQDKDFR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BCHN_ROSCS
Sequence: MSATVIREDGAYHSFCGLTCVGWLYQKIKDSFFLVLGTHTCAHLLQNVLGVMVFARPRFGVALIEEADLSKQQPELNAIIDEIVADHHPSVIFLLSSCTPEVMKVEFDGLARAVSRPNLPVLFVPASGLDYTFSQAEDSVLQALLPFCPVAPADDRRVVFLGSVNDAIADDFHTEAARLGIPVAGFLPESHFRDLPPIGPGTVVAPLQPYLAKVAGRLARERGATVMTSLFPFGPDGTRAFWEDLAAAMGKAVDLSERERQAWERLEPHLEILRGKKVFFTADNLMELPLARFLRNAGCIILECSSPYINRKFHARELAALDGVRVVEQPNFDRQLRDIRALRPDLVISTLATTNPLVGHGVVAKWSTEFSFMPIQGWSGAATLAGMFTRPLKRHAQLDPLMDDPLWVAGLMPG
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: CHLI_CYACA
Sequence: MTSTADVFDKKDQFNFVFPFTAIVGQEEMKISLLLNVVDPKIGGVMIMGDRGTGKTTTIRALVDILPDILVVKDDPYNSHPHDVDLMSSEVQALVLNRMNIETCYTKVPLVDLPLGATEDRVCGSIDIEKALSEGKKSFEPGLLAKANRGLLYVDEINLLDDHLVDVLLDCSASGWNLVEREGISVKHPSKFVLIGSGNPEEGELRPQLLDRFGLHAEIKTVKDPELRVKIVEERTEFDKDPVAYIRKFSKSQDELREKIINAQNLLPKVEMPRELKFNISKICGILDIDGLRGDIVTNRASKAYAAIQQRNVVEIGDIQKVIVSCLRHRLRKDPLEIIESGEKIQKAFTNIF
What is the function of this protein?
Involved in chlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
What are the official names of this protein?
Magnesium-chelatase subunit ChlI, Mg-protoporphyrin IX chelatase.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NU2M_SACLE
Sequence: MNPLILIMIMLTVILGTTIVMMSSHWLMIWMGFEMNMLAVIPLLMKQYNPRSMEAATKYFLTQATASMLLMLAIIINLLYSGQWTFTKLMNPTASIIMTLAMAMKMGLAPLHFWVPEVTQGISLSSGLILLTWQKLAPLSVLYVISPGINLDLILLMSMMSIAIGGWGGLNQTQLRKILAYSSIAHMGWMASILAFNPTMTLLNLLLYILMTTTTFMLFMATSATTTLSLSHMWNKMPLITSSTLTIMLSLGGLPPLVGFLPKWMIIQELTKNNNITLATLMAITALLNLFFYMRLTYATSLTMFPTMNNMKIKWQFNNKKQMKYLPMLIILSTITLPLAPAITLLN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y4034_PSEE4
Sequence: MKRICSIYKSPRKNEMYLYVLKADGLERVPEGLLPFFGTPVHAFDLVLSPERKLAREDIAKVLENLDSQGYHLQMPPPDDDYIEHLPEELLRRNDPA
What are the official names of this protein?
YcgL domain-containing protein PSEEN4034.
Protein: ADCA_STRP8
Sequence: MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRSITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTKKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH
What is the function of this protein?
Part of the ATP-driven transport system AdcABC for zinc.
What are the official names of this protein?
Zinc-binding protein AdcA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family.
Protein: AROC_SHIF8
Sequence: MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLSEKFGIEIRGCLTQMGDIPLEIKDWSLVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGIFGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: MATK_JURCY
Sequence: MDKFQSYLGLDRSQQHYFLYPLIFQEYIYVLAHDHGLNRSILLENAGYDNKSSLLIVKRLITRMYQQNHLILSVNDSKQTPFLGHNKNFYLQVMSEVSSIIMEIPLSLRLISSLEKKGVVKSDNLRSIHSIFSFLEDNFLHLNYVLDIPIPYPAHLEILVQALRYWIKDASSLHLLRFFLHECHNWDSLITSNSKKASSSFSKRNHRLFFFLYTSHVCEYESGFIFLRNQSSHLRSTSSGALLERIYFYGKLEHLAEVFARAFQANLWLFKDPFMHYVRYQGKSILASKGTFLLMNKWKYYFVNFWKSYFYLWSEPGRIYINQLSNHSLDFLGYRSSVRLKPSMVRSQMLENAFLINNAIKKFDTIVPIMPLIGSLAKSKFCNTLGHPIGKVIWANLSDSDIIDRFGRIYRNLSHYHSGSSKKKSLYRVKYILRLSCARTLARKHKSTVRAFLKRFGSELLEEFFTEEEQVFSLTFPKVSSISRRLSRRRIWYLDIICINDLANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACPS_PARUW
Sequence: MTLGIGNDIIEIERIQANIKKYGQRFLNRVFTKNEQIYCLNRKMPALHLAGRFAAKEAVVKALGTGFSQGISWLDVEILNDANGKPYVSISPLLTQLFASPKLLISISHCHHYATAFAVWSS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STMN3_HUMAN
Sequence: MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG
What is the function of this protein?
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.
What are the official names of this protein?
Stathmin-3, SCG10-like protein.
What is the protein family that this protein belongs to?
Belongs to the stathmin family.
What are the subcellular locations of this protein?
Golgi apparatus. Cell projection, growth cone. Cell projection, axon. Cytoplasm, cytosol.
Protein: DAPE_ZYMMO
Sequence: MTIAPDPVDLAARLIACKSVTPSDDGAMNIMADALKSAGFTVHLLTKGQAPDGPVTNLIAIRGEGYPHLAYAGHSDVVPAGQGWSSDPFTPTIKDGYLVGRGAVDMKSSVAAFIAAASRYTEHKGTLSLLITGDEEGPATFGTPAIIEWLNEQSIKPDYCLVGEPTSVERLGDTVKNGRRGSVNMWIEVEGIQGHVAYPDRACNPIPVLARIISDLESWVLDKGDQWFQPSNLEVTSIECDNKATNVIPALAKAQLNIRFNALHKGAELVDSLKKRVAAIDPKARVKAAISGEAFVTEEGVLTDTISAAIAKNTGITPSLSTSGGTSDARFLTKLCPVVEFGLVNATMHKVDEKASVEDIRQLSRIDEDIIKSFLG
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: WDR12_DICDI
Sequence: MESENKNNNKKVKEESKVKVKFITNDANIRVTDTPIAVPVRLGRLGLSEVIHHLREEENETSKPFDFLINGKFIRTTLDKHIKNANLSEEQIITIEYLEAITEPKREKECQHDDWVSCVDGSNFGLVVSGSYDLGVRVWGYDGELISTGTGHLAGVKSVCWISDKNADNLSFVSASMDKTLRVWNFNKSQSEIKALACLKEHTGTIESVYVSPDSSRIVSASMDSTIKLWSIKDIPNQHATTSSSIEKSNSKKRRLANNTNNETAAVDQQSEIIHNITESLASVTVPNSQGVTVVNWTTQFQMLSGSMDSKIRLWDVSTLVANDTIPTPAPLTDLDYSMESGLIVTAHKDRIVRIWDPRSSDETKSQTQSLISHKTWVTSVNWNPSSKYHCCSTSHDGTVKYWDIRTKIPLYTIDTLEKSKDKVLSSSFISNKNKNINDYSIVSGGTDSKLRIHYNDKQEQQQ
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein WDR12 homolog, WD repeat-containing protein 12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: MYG_AILME
Sequence: GLSDGEWQLVLNVWGKVEADLAGHGQEVLIRLFKGHPETLEKFDKFKHLKSEKGSEDLKKHGNTVETALEGILKKKALELFKNDIAAKTKELGFLG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ARGD_THEMA
Sequence: MYLMNTYSRFPATFVYGKGSWIYDEKGNAYLDFTSGIAVNVLGHSHPRLVEAIKDQAEKLIHCSNLFWNRPQMELAELLSKNTFGGKVFFANTGTEANEAAIKIARKYGKKKSEKKYRILSAHNSFHGRTLGSLTATGQPKYQKPFEPLVPGFEYFEFNNVEDLRRKMSEDVCAVFLEPIQGESGIVPATKEFLEEARKLCDEYDALLVFDEVQCGMGRTGKLFAYQKYGVVPDVLTTAKGLGGGVPIGAVIVNERANVLEPGDHGTTFGGNPLACRAGVTVIKELTKEGFLEEVEEKGNYLMKKLQEMKEEYDVVADVRGMGLMIGIQFREEVSNREVATKCFENKLLVVPAGNNTIRFLPPLTVEYGEIDLAVETLKKVLQGI
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_MYCLB
Sequence: MTDIVVAIDGPAGTGKSSVSRGLARELGARYLDTGAMYRMMTLAVLRAGIDPADAAAIGESVWKVQMLSDHDRYFLGGEDVSSEIRTEEVTQAVSAVSAIPAVRVRLVDLQRQMAEGRGSVVVEGRDIGTVVLPDAPVKIFLTASPETRARRRNDQNVASGSADDYDRVLAEVRRRDHLDSTRAVSPLYVAQDAMIVDTSKMAEAEVIAHLMDLVKQRSGAVW
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCS15_ARATH
Sequence: MEKEATKMVNGGVKSKSPKGSPDFLGYNLRYVKLGYIYLLSLSRTFCFFLPPLLLLFIFVSRFLPILAFPLSTFFILLIYHYLTPSSVFLLDFSCYRPPDHLKITKSDFIELAMKSGNFNETAIELQRKVLDQSGIGEESYMPRVVFKPGHRVNLRDGREEAAMVIFGAIDELLAATKINVKHIKILVLNCGVLNTTPSLSAMVINHYKLRHNTESYNLGGMGCSAGVIAIDLAKDLLNAHQGSYALVVSTEIVSFTWYSGNDVALLPPNCFFRMGAAAVMLSSRRIDRWRAKYQLMQLVRTHKGMEDTSYKSIELREDRDGKQGLYVSRDVMEVGRHALKANIATLGRLEPSFEHICVLASSKKVLDDIHKDLKLTEENMEASRRTLERFGNTSSSSIWYELAYLEHKAKMKRGDRVWQIGFGSGFKCNSVVWKALKNIDPPRHNNPWNL
What are the official names of this protein?
3-ketoacyl-CoA synthase 15, KCS-15, Very long-chain fatty acid condensing enzyme 15, VLCFA condensing enzyme 15.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GSEA_STAES
Sequence: MKKRFLSICTMTIAALATTTMVNTSYAKTDTESHNHSSLGTENKNVLDINSSSHNIKPSQNKSYPSVILPNNNRHQIFNTTQGHYDAVSFIYIPIDGGYMSGSGVVVGENEILTNKHVVNGAKGNPRNISVHPSAKNENDYPNGKFVGQEIIPYPGNSDLAILRVSPNEHNQHIGQVVKPATISSNTDTRINENITVTGYPGDKPLATMWESVGKVVYIGGEELRYDLSTVGGNSGSPVFNGKNQVIGIHYGGVDNKYNSSVYINDFVQQFLRNNIPDINIQ
What is the function of this protein?
Exhibits a significant hydrolytic activity for the carbonyl side of glutamic acid.  Shows activity toward human fibronectin and type 1 collagen (By similarity).
What are the official names of this protein?
Glutamyl endopeptidase, Glutamic acid-specific protease, GluSE.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEFI_CALVI
Sequence: ATCDLLSGTGANHSACAAHCLLRGNRGGYCNGKAVCVCRN
What is the function of this protein?
Antimicrobial peptide mostly active against Gram-positive bacteria (Ref. 1, PubMed:26177023).  Active against Gram-positive bacterium M. luteus and also against fungus N. crassa (Ref. 1).  Has no activity against Gram-negative bacterium E. coli (Ref. 1).  Active against M. luteus and, weakly, against E. coli (PubMed:26177023).
What are the official names of this protein?
Defensin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYD_MACCJ
Sequence: MDNRTTYCGLVTESYIGQEIILKGWVQKRRDLGGLIFIDLRDREGVVQIVFNPDFSKEALTIAETIRSEYVIEVHGKVTMRDEAVINPKIKTGKVEVQVSEVTIINKSETPPFQIEAETDSSEDVRLKYRYLDLRREPLANTFKMRHQITRAVRNYLDESGFYEVETPVLTKSTPEGARDYLVPSRVQEGEFYALPQSPQIFKQLLMIGGFDKYYQIVKCFRDEDLRADRQPEFTQIDIEMSFVDQEDVMSMNEGMLKRIMKDVKGIDIATPFPRMTYEEAMRDYGIDKPDTRFDMKLVTLNDLASKMEFKVFKGAVESGGAVKAIVVKGASDKYSRKDIDALQEYAKIYGAKGLAWVKVTEDGLNGPIAKFFEESHASELLDATNAEMGDLILFVADKWSVVNASLANLRNKLGKELGLIDENKYNFLWVTDWPLFEYDEELDRYFAAHHPFTAPKKEHVEMLKTDKEKVQANAYDVVLNGYELGGGSIRIHDQEMQKKMFEALGFSDEEAQEQFGFLMDAFKYGAPPHGGIALGLDRMVMLLSGRSNLRDVIAFPKTASATCLLTDAPSKVDDKQLEELHIQLNIENSEK
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIVIB_BREBN
Sequence: MAVYEERIPQVKQQRPRRRGNRKLVFLLVLFFLTILIIVFIRSPYSKVQEIRVTGNDIYTTEQVITESGLMKDMQFLNVWENSVRNNLKPLEAIKDVTVSRSFPGLITLHITEQKRVAFWSGQDGSRYALLDNGYVLKQVNFAKRVVDRPLISSWASPELLPHLAKSLSKLSPNVLAEISDITLTPTVYDKQRITLYMRDGNEVRSVIYKLDKMMNWYPAIMKQLPPDTKGVLSLFEQPWFIPYGAQGAIPIQEGQEQPQQPQQ
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: SYL_AZOC5
Sequence: MSTDRYNARDAEPRWQAIWNERGIFRTRNDDPRPKFFVMEMFPYPSGRIHIGHGRNYVMGDVLARYKRMQGFNVLHPMGWDSFGLPAENAAIERGIHPKSWTYENIASMKEQLQLLGLSLDWNREVATCDPSYYAEQQRLFLDLFENDLAYRKESEVNWDPVDNTVLANEQVIDGRGWRSGAVVERRKLNQWFFRITAFAQELLDAIDTLDRWPDKVRLMQRNWIGRSEGLEVLFELSKGSVAAAGTSAVKVYTTRPDTLFGASFLALSPDHPLTQHLAATRPDLAAFVADCKTGGTSAEAIETQEKKGFDTGLTVVHPLDAARTVPVYVANFVLMDYGTGAIFGCPAHDQRDLDFARKYGLTVTPVVLPPGADPAVFAVGSEAYDGEGTLYNSQFLDGLSIADAKEQVARRLERFRVGEQPQGTRKVNFRLRDWGISRQRYWGCPIPIIHCDSCGPVAVPREQLPVELPDDVTFDRPGNPLDRAKAWRDVPCPKCGAPARRETDTMDTFVDSSWYFLRYASDNPDKPLDKDAVRHWLPVDQYIGGIEHAILHLLYSRFFTRALKACGRVDVAEPFAGLFTQGMIVHETYKDKDGRWLFPEEVKLLGDGKAEKLDDGSPVTVGPPEKMSKSKKNVVPPEVVVDTYGVDAGRWFMLSDTPPERDSEWTQSGIEGAWRFVQRVWRQVQEAIELGAPKGADKPASFDAAATALRRAAHGLAHQVADDVERLRFNVAVAHVHEFANAFGQAIASARTASPVPADLAFALREAAEIVTRVVGPMVPHLAEECWAALGYDTLLAEAAWPKAEPELLVENTITLPIQINGKKRDDITVPRDATAAEVEAAVLEMESVRRALDGKAPKRIIVVPQRIVNVVA
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_ONYPE
Sequence: MTKKDYYHILGLDKDASPEDIKKAYRSLAKKYHPDISKEANAENKFKEVQEAYSVLGDASKKSNYDRFGDASDNGFSGFGGGGFDGFDSFGDSFFSSFGDIFGNQQTKKPSYDKKVEMTISFMDAVLGANKTIEITVEADCRVCHGKGAVSNQDVITCKRCGGNGQIITEQRTFLGNIRSRQVCPNCSGKGQEIKNKCYACHGQKRQKVKQSATFNIPAGIQEGMSLQVPGKGNFVPLSNNQKRRRSILLTFNSASS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity).
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_POLNS
Sequence: MPRRRKVPKREILPDPKFGNVEVAKFMNVLMLDGKKSVAERIVYGAFDHIEKKANKEPLEIFSTAMGNVKPMVEVKSRRVGGANYQVPVEVRPSRRSALAMRWLREAAKKRGEKSMAQRLANELLEAAEGRGGAMKKREEVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: OGT_SALTY
Sequence: MLRLLEEKIATPLGPLWVVCDEQFRLRAIEWEQYRDRMEQLLNIHYRHEGYERVSATNPGGLSDKLADYFAGNLAVIDTLETATGGTPFQREVWQALRAIPCGQVMHYGQLAAQLGRPGAARAVGAANGANPISIVVPCHRVIGRNGTLTGYAGGVQRKEWLLRHEGYLLL
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_SULTO
Sequence: MILSLDRQIPLSTLSEINKYIHKVKIGYPLILENIEYLDDIVKLHWDEIIFDLKLADIDNTMVLIVSKFINYADSFIAHSFIGIEGALDKLSEFLKNQNKSLYLVLSMSHKGWNDEFYPYLKNIAKTIDPKGFVVGATRPNMIRIVRNDFRDKIIISPGVGAQGAMIGDAICNGADYEIIGRSIYESKDPVTETKKIIETQEVKINECKRTEN
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: TMM54_HUMAN
Sequence: MCLRLGGLSVGDFRKVLMKTGLVLVVLGHVSFITAALFHGTVLRYVGTPQDAVALQYCVVNILSVTSAIVVITSGIAAIVLSRYLPSTPLRWTVFSSSVACALLSLTCALGLLASIAMTFATQGKALLAACTFGSSELLALAPDCPFDPTRIYSSSLCLWGIALVLCVAENVFAVRCAQLTHQLLELRPWWGKSSHHMMRENPELVEGRDLLSCTSSEPLTL
What are the official names of this protein?
Transmembrane protein 54, Beta-casein-like protein, Protein CAC-1.
What is the protein family that this protein belongs to?
Belongs to the TMEM54 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL20_BURM7
Sequence: MPRVKRGVTARARHKKIINLAKGYRGRRNNVYRIAKQAVMRAGQYAYRDRRNKKRVFRALWITRINAAVRQHDMTYSVFINGLKKASIELDRKVLADMAVFDKAAFAAIVKQVKAAVAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NUOCD_SALG2
Sequence: MTDLTAQDAAWSTRDHLDDPVIGELRNRFGPDAFTVQATRTGIPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHLISIERNRDIMLKVALSENDLRVPTFTKLFPNANWYERETWEMFGIDIEGHPHLTRIMMPQTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEALTFKPEDWGMKRGTDNEDFMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLEWMPKRLDSYEKAALRNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKWRPYSGYENFDFEVPVGGGVSDCYTRVMLKVEELRQSLRILQQCLDNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPAQESFQMVEATKGINSYYLTSDGSTMSYRTRVRTPSFAHLQQIPSAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CA1B_CONPU
Sequence: QSPGCCWNPACVKNRC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin causes paralysis upon intramuscular injection into goldfish and blocks both fetal (alpha-1/beta-1/delta-gamma subunits) and adult (alpha-1/beta-1/delta-epsilon subunits) subtypes of vertebrate muscle nAChRs in a dose-dependent manner.
What are the official names of this protein?
Alpha-conotoxin PIB.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.