PharMolix/UniProtQA huggingface dataset:
Protein: FTHS_ALIFM
Sequence: MKSDIEICQTATLTRMKTIASNLGLHDDDITPQGPFKAKVNIDALKRLKSEPNGKLILVSAITPTPLGEGKTVTTIGLAQGLAKLGESVSACIRQPSMGPVFGVKGGAAGGGYSQVAPMEELNLHLTGDIHAITAAHNLASAAIDARIYHEQRLGYDVFSEKNQLPALRIDPQRVVWKRVMDHNDRALRMVTIGKNEDGKTINGYEREDGFDITAASELMAILALATDLQDLRQRIGRIVVAYNLDGEPVTTEDLQVAGAMTVTMKFAINPTLMQTLEGVPTFVHSGPFANIAHGNSSIIADNIALKLTDYTVTEGGFGSDMGFEKACNIKAPLSEKSPDCAVLVATLRGIKANSGLFPLSPGQSLPKELFAPNKEALDAGLDNLLWHINNCAKYGLPVVVAINRFPEDTQEELDSLLNWVSNLDINVDVAISEAFVKGGNGTLELAEKVIKACQQETQFTPLYTSEMSLFDKLNAVAIKGYGAERIELSEKAQQQLATFEKLGYQSLSVCMAKTPASISTDGNIKGAPTDFVVPIRELKLCAGAGFIYALCGNVMTMPGLPEKPAFMNLDIDGDGNIVGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: DAPA_RICPU
Sequence: MHNIFKGLITALITPFKDNKLDLYALERIVKHQIKHEVDAVLIAGSTGESSSLSFEEYKLLLQTSVEIVNKCIPIISGCSSNNTTYARALAAESTKIGVDGFMASPPSYVKPTQHGIYKHFEALHEACNLPIMLYSAPTRSGVDFSDETILRLSKLPRIVALKDCGVDLERPLRIRATVKKDFNILTGNDEVVLAFNAQGGVGWTSVASNIVPNICKELLEKWNKNDTKGALEIHQKLLPLYTALFVESNPIPIKYAAYYLGLCENEIRPPLTEARDSAKKQIENIITSLSIKI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_SULTO
Sequence: MSQQQQFKYIVRLFGQDVDGTMKVPYALAMVKGIGYNTARAIVFKLGLDKDRRLGELSDEDIKKIENYLTDKKILEVPNWMYNRRKDYESGIDMHLVTSDLIFYVRNDIEREKKIKSWRGVRHSLGLKVRGQRTRTTGRTGVTVGVRRSKAAQAAQQQQKAQASSGGEKKQG
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: LPPC_MYCBO
Sequence: MTSTLHRTPLATAGLALVVALGGCGGGGGDSRETPPYVPKATTVDATTPAPAAEPLTIASPMFADGAPIPVQFSCKGANVAPPLTWSSPAGAAELALVVDDPDAVGGLYVHWIVTGIAPGSGSTADGQTPAGGHSVPNSGGRQGYFGPCPPAGTGTHHYRFTLYHLPVALQLPPGATGVQAAQAIAQAASGQARLVGTFEG
What are the official names of this protein?
Putative lipoprotein LppC, UPF0098 protein Mb1946c.
What is the protein family that this protein belongs to?
Belongs to the UPF0098 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PYRD_NITEC
Sequence: MTYTLLRPLLFLLDAETAHTLTLDTLGLLQKTGLLPNRTIYCTPVRAMGLDFPNPVGLAAGLDKNGAYISALARLGFGFIEVGTVTPRPQPGNPRPRLFRVPQAEAITNRMGFNNVGIDKLIENVRQADYQGILGINIGKNADTPLQNAIDDYLICLRKAYPYASYVTVNISSPNTKQLRQLQNETELEQLLGALKTEQTRLSDQHGHYTPLAIKIAPDLESAQIEAIASLLLKHRMDAVIATNTTIARDGLEHLPHGDEPGGLSGAPLTERSTAVIRQLAMHLQQAIPIIGAGGIMSSLDAQAKIKAGASLVQVYSGLIYRGPALVSEITSLLCSRSTYAG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y4252_SHESH
Sequence: MMDNNEPISAEHGQAGENLAMNYLLEQGLTFIERNVRFKFGEIDLVMKNGKEWIFVEVKYRSKSQYGGAINALSSGQIKRLRRAAEHYMQLNNIDAICRFDLIAVDAGQIQWLPNAF
What are the official names of this protein?
UPF0102 protein Ssed_4252.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: KUNI_ARGMO
Sequence: MRLLALFAFAVAVVSAQRNQMCQQPRTQGSCDASNQITKFFYTGSGCTSAPVCSDTDGGYGTEDECIQACTVQGGHHNEGAGEEGCSGDPPRGDCGGQVEERYYFDSTTRTCQTFEYRGCSSGNPDNSYETEIECEIACPSASS
What is the function of this protein?
Tick salivary thrombin inhibitor that plays an important part in the anti-hemostatic strategy of ticks.
What are the official names of this protein?
Monobin, Thrombin inhibitor.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Secreted.
Protein: PR40A_HUMAN
Sequence: MRPGTGAERGGLMVSEMESHPPSQGPGDGERRLSGSSLCSGSWVSADGFLRRRPSMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQMPGMMSSVMPGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ
What is the function of this protein?
Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity).  Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the control of cell shape and migration.  May play a role in cytokinesis.  May be involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-processing factor 40 homolog A, Fas ligand-associated factor 1, Formin-binding protein 11, Formin-binding protein 3, Huntingtin yeast partner A, Huntingtin-interacting protein 10, HIP-10, Huntingtin-interacting protein A, Renal carcinoma antigen NY-REN-6.
What is the protein family that this protein belongs to?
Belongs to the PRPF40 family.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus matrix. Note=Colocalizes with AKAP8L in the nuclear matrix.
Protein: SYVN1_DANRE
Sequence: MVRAALVTATSLALTGAVVAHAYFLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKLMRKVFFGQLRAAEMEHLIERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMERSPNISWVFHFRVLSLMVLLGVMDFLFVNHACHSIITRGASVQLVFGFEYAILMTMVLTTFIKYTLHTIDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEDLQATDNVCIICREEMVTGAKKLPCNHIFHSSCLRSWFQRQQTCPTCRMDVLRASQPNQTPAPPAAQAPAPPAPANAPIPPPVNVAPGMIPQFPPGLFPFWGPFPGAPPPAVPGAPAAPTDTPQPSSDGAQGAESGAGGLAQSTAEAASAAPGAMPGFPFTMPPPFPSAPWLPMPPPPPFMSSMPPPPSSLSSMSEAELRELEQEGRRGLEARLQCLHNIHTLLDAAMLNIHHYLSTVATLSPPRSETNTGETSESANVESSPSTANTETAGQEIQSQSGESINGAAGFSQPDSTTEGEKDVKEEDEDDGEPSAAELRRRRLRKLETTNTPDHGNLLKLASVN
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation.  Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.  Also promotes the degradation of normal but naturally short-lived proteins.  Protects cells from ER stress-induced apoptosis.  Sequesters p53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase synoviolin, RING-type E3 ubiquitin transferase synoviolin, Synovial apoptosis inhibitor 1.
What is the protein family that this protein belongs to?
Belongs to the HRD1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y1178_METTH
Sequence: MPRPRRFRRILGEPRVVTFSPEASDEETGVEITLDEFEAIRLRDYHDIKQKKAAEIMGISQPTFHRTLTSARGKIAAALVEGRPIILKGGDYITDRRRYKCMDCQFEWISPEKEYKKCPDCGSENINVVSAETIPRFGRGGYGRGFGAGRGAPRVCKCIECGYEAPKTPGVPCRTEKCPKCGAPMCGAD
What are the official names of this protein?
UPF0251 protein MTH_1178.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: GSA1_STAA9
Sequence: MRYTKSEEAMKVAETLMPGGVNSPVRAFKSVDTPAIFMDHGKGSKIYDIDGNEYIDYVLSWGPLILGHRDPQVISHLHEAIDKGTSFGASTLLENKLAQLVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIVKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLDALKIAFEKFGDDIAGVIVEPVAGNMGVVPPIEGFLQGLRDITTEYGALLIFDEVMTGFRVGYHCAQGYFGVTPDLTCLGKVIGGGLPVGAFGGKKEIMDHIAPLGNIYQAGTLSGNPLAMTSGYETLSQLTPETYEYFNMLGDILEDGLKRVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEQANKSDLKLFAEMYREMAKEGVFLPPSQFEGTFLSTAHTKEDIEKTIQAFDTALSRIVK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOS_MOUSE
Sequence: MPSPLSLCRYLPRELSPSVDSRSCSIPLVAPRKAGKLFLGTTPPRAPGLPRRLAWFSIDWEQVCLMHRLGSGGFGSVYKATYHGVPVAIKQVNKCTKDLRASQRSFWAELNIARLRHDNIVRVVAASTRTPEDSNSLGTIIMEFGGNVTLHQVIYGATRSPEPLSCREQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILISEQDVCKISDFGCSQKLQDLRCRQASPHHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSGEPQYVQYAVVAYNLRPSLAGAVFTASLTGKTLQNIIQSCWEARALQRPGAELLQRDLKAFRGALG
What are the official names of this protein?
Proto-oncogene serine/threonine-protein kinase mos, Oocyte maturation factor mos, Proto-oncogene c-Mos.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: ASP23_STAHJ
Sequence: MSVDNNNKAKQAYNNQTGVNEKEREEQQKQAEQYREQNEQQQFENKLTFSDEVVEKIAGIAAREVKGILDMKGGFADNFTNAFSSGNNVTTGVSVEVGEKQAAIDLKVILEYGESAPKIFRKVTELVKEQVKYITGLQVVEVNMQVDDVMTKKEWQQKNEKNNNNNNNNSERSGLQ
What is the function of this protein?
May play a key role in alkaline pH tolerance.
What are the official names of this protein?
Alkaline shock protein 23.
What is the protein family that this protein belongs to?
Belongs to the asp23 family.
Protein: RNH_ECOL5
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP1_ASPFL
Sequence: MRFSAIFTLGLAGTALATPLVERAGSSPTDIISGISDKTDALDSAIKAYNGGDPSKVESASADLISTITKGTDAIKSGDDISTTDALALPEPVQALTKKVEQAIDDIIAKKDKFVEAGAGGKVKDSLNQQKSAADGLASAITSKVPESLKEIAQSLSAGISTAIQKGVDAYKDVSDSAPSSSAGSSASATATGSASETGSASTTGSASATSSSVIPTSSGAASSSAAPSGSSTPTGSGSASATSPPLATGAANKATIGYSLGAVAMAAIAVAV
What is the function of this protein?
Constitutive protein of the cell wall (By similarity).  Antigen target of host humoral immune response.
What are the official names of this protein?
Cell wall mannoprotein 1.
What is the protein family that this protein belongs to?
Belongs to the cell wall mannoprotein 1 family.
Protein: Y4868_NOCFA
Sequence: MRARCGRILSDSERVEADMDTGMGGMDFGTVDAVAGQVAGNLAVSEATIADLGYLRAQLAAAEVPFLLVRDRDHRLVLAADAAHRAMVRRVTAAAAAAGFVCTQPQPDVVRLGRDRDPAHHVELELWEYHGDTVECPRPNALTRTVFDLADVEFTEVRLFDRSWPTLAQMFAPQPTDVGFDIDIVFSWVDGSDPEFRARRAGMMAQVVVGEGDDADARIRQIDELKYALRSVHKNAPWIRRIFIATDSPAPAWLAEHPKVTIVRAIDHFSDTSGLPTFNSHAVESQLQHIEGLSEHFLYSNDDMFFARPVRPSMFFTPAGISRFIEADVRIGPGRNNERRSGYENAARVNRALLAERFGHVITRHLEHTPVPLRRSVLREMEEEFAADFARTRTSRFRAATDISVTNSLYHYYALLTGRAVPQEAARVAYVDTTSRAGLAVLDDIAAHRDLDFFCLNDGSFPEISESERVREVSRFLAGYFPDPAPWERVSAPSRRPLPESTAGAA
What are the official names of this protein?
Exopolysaccharide phosphotransferase NFA_48680, Stealth protein.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: RRAA_ECOSE
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_ALIFM
Sequence: MKVGIHPEYTAVKATCSCGNEFEFNSALGKDSIHLDVCDKCHPFYTGKQRIVDTGGRVDRFNKRFGAIGSKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: LPQB_MYCBP
Sequence: MERLMRLTILLFLGAVLAGCASVPSTSAPQAIGTVERPVPSNLPKPSPGMDPDVLLREFLKATADPANRHLAARQFLTESASNAWDDAGSALLIDHVVFVETRSAEKVSVTMRADILGSLSDVGVFETAEGQLPDPGPIELVKTSGGWRIDRLPNGVFLDWQQFQETYKRNTLYFADPTGKTVVPDPRYVAVSDRDQLATELVSKLLAGPRPEMARTVRNLLAPPLRLRGPVTRADGGKSGIGRGYGGARVDMEKLSTTDPHSRQLLAAQIIWTLARADIRGPYVINADGAPLEDRFAEGWTTSDVAATDPGVADGAAAGLHALVNGSLVAMDAQRVTPVPGAFGRMPEQTAAAVSRSGRQVASVVTLGRGAPDEAASLWVGDLGGEAVQSADGHSLLRPSWSLDDAVWVVVDTNVVLRAIQDPASGQPARIPVDSTAVASRFPGAINDLQLSRDGTRAAMVIGGQVILAGVEQTQAGQFALTYPRRLGFGLGSSVVSLSWRTGDDIVVTRTDAAHPVSYVNLDGVNSDAPSRGLQTPLTAIAANPSTVYVAGPQGVLMYSASVESRPGWADVPGLMVPGAAPVLPG
What are the official names of this protein?
Lipoprotein LpqB.
What is the protein family that this protein belongs to?
Belongs to the LpqB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PETD_PROM1
Sequence: MSTLKKPDLTDTKLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACVVGLAVLDPAFLGDKANPFATPLEILPEWYLYPVFQILRVVPNKLLGIALQTLIPLGLMILPFIENINKFANPFRRPVAMSLFLFGTVLTMYLGIGACLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: FPG_VARPS
Sequence: MPELPEVEVTRRGFAERIAGARIDAVRIGKPLRWALMVMPEALVGRRVLQVRRRGKYLLIDLDRGLLLLHLGMSGSLRFDAALPAPGVHDHFDLVTELGTLRLNDPRRFGAVVYVEDEAAPWAIKLLGGLGMEPLGDAFDLDAFHAGLRKRKAAVKQVLLAGDVVVGVGNIYASEALFLAGIRPTLSAARISRPRAARLHAAVREILARAVEKGGSTLRDFSNVEGQSGYFQLEATVYGRAGEPCRVCATPIRLLRQGQRSTYYCPNCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PHOP_SALTI
Sequence: MMRVLVVEDNALLRHHLKVQLQDSGHQVDAAEDAREADYYLNEHLPDIAIVDLGLPDEDGLSLIRRWRSSDVSLPVLVLTAREGWQDKVEVLSSGADDYVTKPFHIEEVMARMQALMRRNSGLASQVINISPFQVDLSRRELSVNEEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPHDVITTVRGQGYLFELR
What is the function of this protein?
Member of the two-component regulatory system PhoQ/PhoP which regulates the expression of genes involved in virulence and resistance to host defense antimicrobial peptides.  Promotes intramacrophage survival of S. typhi.  Is required to enhance bacterial resistance to bile in the human intestinal cells.
What are the official names of this protein?
Virulence transcriptional regulatory protein PhoP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_BURL3
Sequence: MPMPLDDSTLSLLPDHPLAAHNTFGIAATARFAARITHASQFEALHRDPRVAHLPQLVLGGGSNVVFTRDFDGVVLLDEIAGRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMAGLENLALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGCSERFDAARCAFGYRDSFFKREGRGRFAIVSVTFRLPKQWVPRLGYADVTRELDARGIAPDAATARDVFDAVVAIRRAKLPDPLVLGNAGSFFKNPVIDAAQFDALRARAPEVVSYPQPDGQVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATGADVLALARAIQADVQTQFGVELEAEPVCL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VHLP_ASFB7
Sequence: MSTKKKPTITKQELYSLVAADTQLNKALIERIFTSQQKIIQNALKHNQEVIIPPGIKFTVVTVKAKPARQGHNPATGEPIQIKAKPEHKAVKIRALKPVHDMLN
What is the function of this protein?
DNA-binding protein that plays a critical role in nucleoid compaction, genome replication and DNA replication and transcription (PubMed:28381576).  Binds to both ssDNA and dsDNA with a binding site covering about 15 nucleotides (PubMed:28381576).  Displays DNA-supercoiling activity only when associated with the viral DNA topoisomerase 2 (PubMed:28381576).
What are the official names of this protein?
Viral histone-like protein, DNA-binding protein pA104R, pA104R.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with viral nucleoid.
Protein: CADH_PINTA
Sequence: MGSLESEKTVTGYAARDSSGHLSPYTYNLRKKGPEDVIVKVIYCGICHSDLVQMRNEMGMSHYPMVPGHEVVGIVTEIGSEVKKFKVGEHVGVGCIVGSCRSCGNCNQSMEQYCSKRIWTYNDVNHDGTPTQGGFASSMVVDQMFVVRIPENLPLEQAAPLLCAGVTVFSPMKHFAMTEPGKKCGILGLGGVGHLGVKIAKAFGLHVTVISSSDKKKEEAMEVLGADAYLVSKDTEKMMEAAESLDYIMDTIPVAHPLEPYLALLKTNGKLVMLGVVPEPLHFVTPPLILGRRSIAGSFIGGMEETQETLDFCAEKKVSSMIEVVGLDYINTAMERLEKNDVRYRFVVDVAGSELDN
What is the function of this protein?
Involved in lignin biosynthesis.  Catalyzes the final step specific for the production of lignin monomers.  Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols.
What are the official names of this protein?
Probable cinnamyl alcohol dehydrogenase, CAD.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: VP22_BHV1C
Sequence: MARFHRPSEDEDDYEYSDLWVRENSLYDYESGSDDHVYEELRAATSGPEPSGRRASVRACASAAAVQPAARGRDRAAAAGTTVAAPAAAPARRSSSRASSRPPRAAADPPVLRPATRGSSGGAGAVAVGPPRPRAPPGANAVASGRPLAFSAAPKTPKAPWCGPTHAYNRTIFCEAVALVAAEYARQAAASVWDSDPPKSNERLDRMLKSAAIRILVCEGSGLLAAANDILAARAQRPAARGSTSGGESRLRGERARP
What is the function of this protein?
Tegument protein that plays different roles during the time course of infection (By similarity).  Participates in both the accumulation of viral mRNAs and viral protein translation at late time of infection (By similarity).  Modulates the RNase activity of the virion host shutoff protein UL41 probably to ensure necessary levels of key cellular mRNAs and proteins (By similarity).  Plays a role in microtubule reorganization that occurs after viral infection by stabilizing microtubule network (By similarity).  Plays a role in the inhibition of host innate immune system by targeting the CGAS enzymatic activity which is the principal cytosolic DNA sensor that detects invading viral DNA.  Acts by mediating disruption of liquid-like droplets in which CGAS is activated, thereby preventing CGAS activity (By similarity).
What are the official names of this protein?
Tegument protein VP22.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae VP22 tegument protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus. Host Golgi apparatus. Note=One of the most abundant tegument protein (about 2000 copies per virion). Localizes in the cytoplasm at 8 hours postinfection and in the nucleus at 16 hours postinfection. During virion morphogenesis, this protein probably accumulates at the trans-Golgi where secondary envelopment occurs.
Protein: RS14_HYDCU
Sequence: MAKQSMIEREKKRAKMVAKYSAKRAELKKASVDMSLSFEERMEAMDKLAKLPRNASPVRQQNRCRLTGRPHGVYRKFGLSRNMLRQLAMQGDVPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: COX2_MICPE
Sequence: MAYPFQLGLQDASSPIMEELMNFHDHTLMIVFLISSLVLYIITLMLTTKLTHTSTMDAQEVETIWTILPAVILILIALPSLRILYMMDEINNPALTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATISSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKNFEDWSLSMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NADE_VIBC3
Sequence: MEHKIREEMRVLPSIDPQFEIERRVAFIKRKLTEARCKSLVLGISGGVDSTTCGRLAQLAVEELNQQHNTTEYQFIAVRLPYGEQKDEDEAQLALSFIRPTHSVSVNIKAGVDGLHAASHHALANTGLIPSDPAKVDFIKGNVKARARMVAQYEIAGYVGGLVLGTDHSAENITGFYTKFGDGACDLAPLFGLNKRQVRLLAKTLGAPEQLVYKTPTADLEELAPQKADEAALNLTYEQIDDFLEGKAVPAEVSQRLVAIYHATQHKRQPIPTIYD
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.