PharMolix/UniProtQA huggingface dataset:
Protein: PG095_VARV
Sequence: MGAAASIQTTVNTLSERISSKLEQEANASAQTKCDIEIGNFYIRQNHGCNLTVKNMCSADADAQLDAVLSAATETYSGLTPEQKAYVPAMFTAALNIQTSVNTVVRDFENYVKQTCNSSAVVDNKLKIQNVIIDECYGAPGSPTNLEFINTGSSKGNCAIKALMQLTTKATTQIAPRQVAGTGVQFYMIVIGVIILAALFMYYAKRMLFTSTNDKIKLILANKENVHWTTYMDTFFRTSPMVIATTDIQN
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex associated protein OPG095, EFC-associated protein OPG095, Protein L1, Virion membrane protein M25.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG095 family.
Protein: ARGJ_LISIN
Sequence: MELIKGNIASPKGFYADGKHAGLKRKRNDIGWIYSEVPANSAAVYTMNQMQAAPIFVTKDSFKNSAKLQAIIVNSGNANAVTGNQGMLDALSMRAKTAEKLAIPMDTVAVASTGIIGEMLPMDKIMTGIDLLEKQTGNAADFEEAILTTDTFQKQISFQTEIGGKTVTMSGVAKGSGMIHPNMATMLAFITTDAAIPAELLQKLLKIKVDKTFNQITVDGDTSTNDMVVVMANGCAENPLIQEGTADFEKFAAMFQAVTEHLAKSIARDGEGATKLIEVQVKGATKTEDARMIAKKIVSSSLVKTAAFGGDGNWGRIICAIGYSGGRFAPDNITIKIGGIEILNHSSQTIFNQQALDAYLEEEHIVIEVDLHIGLESGTAWGCDLSYEYVKINACYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_LEGPH
Sequence: MNKELLLGVNIDHIATIRQARGTRYPDPVQAAMDAEEAGADGITLHMREDLRHIQARDVRLIKQVLQTRMNLELAVTEAMLDFAEEISPEHACLVPEKREELTTEGGLDILTHRNVVEKAVRRLQLMGSEVSLFIDPDKEQIRAAVDVGAPVIELHTGCYADATSEEKQHYELQRIKEAAEFAASLNLVVNAGHGLHYHNVKPIAAIRELNELNIGHAIIARALFCGLKEAVRHMRQLMQEARLYVND
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H1L6_ENSMI
Sequence: AKKRSRSRKRSASRKRSRSRKRSASKKSSKKHVRKALAAGMKNHLLAHPKGSNNFILAKKKAPRRRRRVAKKVKKAPPKARRRVRVAKSRRSRTARSRRRR
What are the official names of this protein?
Histone H1-like protein EM6.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NQRB_CHRSD
Sequence: MGIRNTLDKLEPHFHQGGKYEKFYALYEAVDTIFYSPPSVTKSTAHVRDGIDLKRIMITVWLCTFPAMFFGMYNAGLQANMAIGDGFGALGGWREAVTMALAGSHDPGSIWANFVLGATYFLPIYLVTFAVGGFWEVLFAVKRGHEVNEGFFVTSVLYALILPATIPLWQVALGITFGVVIGKEIFGGTGKNFLNPALTGRAFLYFAYPAQISGDSVWVAADGYTGATALSTAAQNGMSAVQQAYSWWDAFLGFIPGSVGETSTLAILIGAAVLLITRIASWRIMLGVFVGMALTAMLFTAIGSESNPMFGMPWYWHLVLGGFAFGMVFMATDPVSASMTDPGKLLFGFLIGVMTVLIRVVNPAFPEGIMLAILFANLFAPMIDHFFVQANIKRRMKRDAAYSPATNEETA
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-NQR subunit B, Na(+)-translocating NQR subunit B, NQR complex subunit B, NQR-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOD_DEHMC
Sequence: MAIKTENFILNIGPQHPSTHGVFRLRIVLDGEVITDLEPVFGYLHRGIEKLAEGRTYLQDIPFTDRLDYLGSMTNNHAYVMAVEKLAGITVPERAEYIRVILDELQRIASHLAGLGFFLNDLGALQTPLLYMFREREKIVELFDMCSGQRLNYNYYRFGGFVQDLPEEFLPALKILLDTLPGFIDEYEQLISTNEIVLIRTKGVGVLKRDLAINSSAAGPVLRASGINWDIRRNDPYSIYNRFEFDIPIAKNGDTYDRYMIRILEMRQSVWILRQAVKDLPEGEIMGKAPKLLKPPAGEVYSRIEGPKGELGFYLVSDGTDKPYRWRVRPPCLLNLSALKDMVVGWKVADLMAIFGSIDIVMGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROC_MYCA1
Sequence: MLRWITAGESHGRALVAVLEGMVAGVEITSTDISEQLARRRLGYGRGARMSFERDAVSVLSGVRHGLTLGGPIAVEIGNTEWPKWETVMATDPVDPAQLADSARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTIARSFLRQALGVEVLSHVIAIGPSAPYEGPPPGPGDLPAIDASPVRAYDEAAEQAMIAEIEAAKKDGDTLGGVVEVVALGLPVGLGSFTSGDNRLDGQLAAAVMGIQAIKGVEIGDGFATARRRGSQAHDEMYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDMATGDEAVAIHQRSDVCAVPAAGVVVEAMVALVLARAALQKFGGDSLAETRRNIDAYRRAVAEREAPAARGTA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: DCE1_MOUSE
Sequence: MASSTPSPATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFRERQSSKNLLSCENSDQGARFRRTETDFSNLFAQDLLPAKNGEEQTAQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSNKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADLEAKILDAKQKGYVPLYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELADYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGVPDSPERREKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
What is the function of this protein?
Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor.
What are the official names of this protein?
Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: LONM1_DICDI
Sequence: MLSINNKLKNLKLSTVKNLYNKSSSISIILVNNNNNNNNNNNNNNNNNNNNNNNNNNFISLSTTNLFNQKLCIESYKKVNYCKKKGGGNKNNDDNDNEKNEKNEKKVKNEKKEKNEKNDGNEKVEIVEDNDLIVPLSKELLQFDKPSNKRKDWPLNSEVVIYPSNSVNFIGTTGPINLGFQFITRLVPNASGKTFLGFFLCKDAYRNNNNQIGRTIDSIHNVGVLAQVTLSPSGIYHFETIKRIRIKEVQNGQFPFIASIEPLSNDERELKDPRIAELMTKINVLSLEYRKLYPDVYTINSVDFENQIEVIDNPDYYLAAVINYYGLNYPDECQKILETQSVVKRLEMLYHMILNEQPLLALQQKIAKDLDDKTTAYKNKLLLTEQLKKLKALLGNETDEKEKTIEKYQNKLSELTLISESSKKVIQDEIYKISTIDPSSSEYSALKNYLEWLTNLPWGIYSADYFDLKHSKMVLDSDHYGLEDIKQRILEFISVGHIKGTVQGKILCFIGPPGTGKTSIAKSIAKALKKEFFRFSVGGLFDESEIKGHRRTYVGSMPGKIIQALKITQTSNPVILIDEIDKIGKRNHGDPSSALLEVLDPEQNVSFVDHYLDTPYDLSKVLFICTANSGQDIPAALSDRMEIIRLPGYVEEEQIEIVKNFIIPKTFIDCGIKLDQLSISDDVIKQIVKFYSREVGIRELEKLIEKIMRKTALKLVNGTAERVDLTLDNLEQYLGIPSYTSDRYYDVTPIGVVNGLAYTKKGGATLYIESTSEEIQKPLSSLPPSQQQQNQLEPSIKTTGNLGDVMSESSTIAYTFAKNFLYELDPNNTFFSNHNIHLHSPQGNIPKDGPSAGVTMVTSLLSLALNEPVQNNLGMTGEVTITGKVITIGGVKEKTIAAKRSGLTSVIFPINNRINFEELPTYIKNDIDVTYANDYKDVFEVAFPNKKYLLNNLKTF
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix.  May also have a chaperone function in the assembly of inner membrane protein complexes.  Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome.  Binds to mitochondrial DNA in a site-specific manner.
What are the official names of this protein?
Lon protease homolog, mitochondrial 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NR2E1_HUMAN
Sequence: MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEENGAAAHFPSAALPAPAFFTAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI
What is the function of this protein?
Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity).  May be required to pattern anterior brain differentiation.  Involved in the regulation of retinal development and essential for vision.  During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity).  May be involved in retinoic acid receptor (RAR) regulation in retinal cells.
What are the official names of this protein?
Nuclear receptor subfamily 2 group E member 1, Nuclear receptor TLX, Protein tailless homolog, Tll, hTll.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NCPR_PHACH
Sequence: MAVSSSSDVIVLSVGIILAALYLFREQIFSAAKPKTVQVPSSKAAAGGNGNPRDFIAKMKEGKKRIVIFYGSQTGTAEEYAIRLAKEAKSKFGLASLVCDPEEYDFENLDQVPEDCCVFFVMATYGEGEPTDNAVQLCQNLSDESFEFSNGEHKLPGLKYVIFGLGNKTYEHYNLISRNVDRDLQKMGAIRIGERGEGDDDKSMEEDYLEWKDGMWEAFAKAMNVEEGQGGDSPDFVVTEVFDHPEEKVYLGELSARALTRTKGIHDAKNPYPAPIIAAKELFAPGSDRNCVHIELSTESSGITYQHGDHVGVWPSNADKEVDRLLYALGLHEKKDTVINIESLDPALAKVPFPVPTTYATVLRHYIDISALAGRQILGVLAKFAPNPEAEAVLKDLNSNKEHYQNIVANGCMKLGEVLQYAAGNDLHADPTASNTTAWKIPFDIIVSSIPRLQPRYYSISSSPKLYPNAIHATVVVLKYKSEKAPRVEERWIYGVGSNFLLNLKYASHHDKAATLVSDDSPSEPSIVSHYPTYSIEGPRGAYKQGDVVKVPIHVRRSTFRLPTNPKSPVIMIGPGTGVAPFRGFVQERVAMARRTIEKHGPEGLADWGPIRLYYGCRRSDQDFLYKDEWPEYAKELHGKFIMRCAFSREPPYKPDGSKIYVQDLIWEDAEQIADAILNGKGYVYICGDAKSMSKSVEETLCRILGEAKGGSAEVEGAAELKLLKERNRLLLDVWS
What is the function of this protein?
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes.  It can also provide electron transfer to heme oxygenase and cytochrome B5.  Involved in ergosterol biosynthesis.
What are the official names of this protein?
NADPH--cytochrome P450 reductase, CPR, P450R.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Mitochondrion outer membrane; Single-pass membrane protein; Cytoplasmic side. Cell membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: ARCA_CHRVO
Sequence: MTKFGVHSECGKLRTVMVCRPGLAHKRLTPDNCHDLLFDDVIWVERAQKDHAYMVEQMRARGIEVIEVHDALAKVLDDKAARNWILDRKVKADNVGIGMLSDLRSWLNEMPSSQLADHLVGGIAKFELPFDPKGLFGGYLDRSDFVLPPIPNSLFQRDPSCWIYEGVTLNPMYWPARRQETLILQSIYQFHPYFAGKVNIWWGGCDTDHGPATLEGGDVMPIGNGVVLIGMGERTSPQAVVQVAKRVLHREGGAKRVIACQMPKSRAAMHLDTVFSFLDIDLLSVFPDVVDEITCTSMYAGDREGEIRFERHEGVKLVDVVREALNLKEIRVIQTGGDAYQREREQWDDGNNVVALDRRVVVAYDRNTYTNRLMREHGVEVIEIPASELGRGRGGGHCMTCPIIRDEVKV
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSG1_HORVU
Sequence: MAALATSQLATSGTVLGVTDRFRRPGFQGLRPRNPADAALGMRTIGASAAPKQSRKAHRGSRRCLSVVVSATGSGMNLVFVGAEMAPWSKTGGLGDVLGGLPPAMAANGHRVMVVSPRYDQYKDAWDTSVISEIKVADEYERVRFFHCYKRGVDRVFIDHPWFLEKVRGKTKEKIYGPDAGTDYEDNQQRFSLLCQAALEAPRILNLNNNPYFSGPYGEDVVFVCNDWHTGLLACYLKSNYQSNGIYRTAKVAFCIHNISYQGRFSFDDFAQLNLPDRFKSSFDFIDGYDKPVEGRKINWMKAGILQADKVLTVSPYYAEELISGEARGCELDNIMRLTGITGIVNGMDVSEWDPTKDKFLAVNYDITTALEAKALNKEALQAEVGLPVDRKVPLVAFIGRLEEQKGPDVMIAAIPEILKEEDVQIILLGTGKKKFEKLLKSMEEKFPGKVRAVVRFNAPLAHQMMAGADLLAVTSRFEPCGLIQLQGMRYGTPCVCASTGGLVDTIVEGKTGFHMGRLSVDCNVVEPADVKKVATTLKRAVKVVGTPAYQEMVKNCMIQDLSWKGPAKNWEDVLLELGVEGSEPGIVGEEIAPLAMENVAAP
What is the function of this protein?
Required for the synthesis of amylose in endosperm.
What are the official names of this protein?
Granule-bound starch synthase 1, chloroplastic/amyloplastic, Granule-bound starch synthase I, GBSS-I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Amyloplast or chloroplast, granule-bound.
Protein: RECF_MYCBT
Sequence: MYVRHLGLRDFRSWACVDLELHPGRTVFVGPNGYGKTNLIEALWYSTTLGSHRVSADLPLIRVGTDRAVISTIVVNDGRECAVDLEIATGRVNKARLNRSSVRSTRDVVGVLRAVLFAPEDLGLVRGDPADRRRYLDDLAIVRRPAIAAVRAEYERVVRQRTALLKSVPGARYRGDRGVFDTLEVWDSRLAEHGAELVAARIDLVNQLAPEVKKAYQLLAPESRSASIGYRASMDVTGPSEQSDTDRQLLAARLLAALAARRDAELERGVCLVGPHRDDLILRLGDQPAKGFASHGEAWSLAVALRLAAYQLLRVDGGEPVLLLDDVFAELDVMRRRALATAAESAEQVLVTAAVLEDIPAGWDARRVHIDVRADDTGSMSVVLP
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESXL_MYCTO
Sequence: MTINYQFGDVDAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSAACQGFITQLGRNFQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA
What are the official names of this protein?
ESAT-6-like protein EsxL.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. ESAT-6 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: MURA_PHOPR
Sequence: MMQKFRIQGGGPLSGEVSISGAKNAALPILFASLLAEKPVEIANVPKLRDIDTTMELLGRLGVNITRNGSVFIDASGVNEFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHIHGLEQLGATITLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTVIENAAREPEIVDTADFLNAIGAKVTGAGTDTITIEGVERLGGGYHEVVADRIETGTFLVAAAVSGGKILCRNTRPALLEAVLAKLEEAGAAIETGDDWISIDMTDRELKAVNIRTAPHPGFPTDMQAQFSLLNLVAKGTGIITETIFENRFMHIPELIRMGARAEIEGNTVICGDTDGGLSGAQVMATDLRASASLVIAGSIAEGETIVDRIYHIDRGYEYIEGKFSALGMNIERISE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_CERSP
Sequence: MRHSTTLTGCATGAAGLLAATAAAAQQQSLEIIGRPQPGGTGFQPSASPVATQIHWLDGFILVIIAAITIFVTLLILYAVWRFHEKRNKVPARFTHNSPLEIAWTIVPIVILVAIGAFSLPVLFNQQEIPEADVTVKVTGYQWYWGYEYPDEEISFESYMIGSPATGGDNRMSPEVEQQLIEAGYSRDEFLLATDTAMVVPVNKTVVVQVTGADVIHSWTVPAFGVKQDAVPGRLAQLWFRAEREGIFFGQCSELCGISHAYMPITVKVVSEEAYAAWLEQARGGTYELSSVLPATPAGVSVE
What is the function of this protein?
Subunits I and II form the functional core of the enzyme complex.  Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome aa3 subunit 2, Cytochrome c oxidase polypeptide II, Oxidase aa(3) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VP53B_ARATH
Sequence: MDKSSGLDFINQMFPVEASLSCVESFMQKICDEIRRVDATILAVVSQQGNSGTRAKENLNDAICAAEELSHKIQEIKSKAEQTEAMVQDICSDIKKLDFAKKNITTAVTALSRLTMLVSAVQQLQVMTSKRQYKEAATQLEAINELCNHFKAYMDLPKIMELREKLKNIKQILKFHVFSDFSSLGTGTETEELFLLKKLSDSCLVVDALEPSVREELINNFCSRELTSYEQIYVGAELKTLDEIELIYNQLSCLIRKNQGKWTIFPASWHVPYRLCIQLSRKTRVQVESILVNLKEKSDVEKLLLELKRTLEFERELEMKFGGGGSIGDDIIGGGGNNSQKFNFRGMISSCFEPHLTIYIEKEEMELMQLLEKVVQEETWDIEEELGCHSENSVYLMLLDAHDMKMILLKVPSLARQPEASALLVKTATASYVKLVNHQMKRAEAVLKVIASPIVTVIDTYRALFPEETPMEFQRILVLKGLTKAEQQSILDDFNNHSSRITQLSVAAKTPEAHALPLALTNVAPAVRFKANSEEVLTRAASAATTSFMKLYALTGAAKDRPFRKLFNP
What is the function of this protein?
Involved in retrograde transport from early and late endosomes to late Golgi, leading to the membrane fusion between late Golgi and endosomal vesicles.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 53 B.
What is the protein family that this protein belongs to?
Belongs to the VPS53 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: EMX2_BOVIN
Sequence: MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAAGRGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDASPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD
What is the function of this protein?
Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain.  May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system (By similarity).
What are the official names of this protein?
Homeobox protein EMX2, Empty spiracles homolog 2, Empty spiracles-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the EMX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: M3A_CONAX
Sequence: CCQWPCSHGCIPCCY
What is the function of this protein?
Does not show any effect on voltage-gated sodium and potassium channels (10 uM of toxin tested), and on nicotinic acetylcholine receptors (5 uM of toxin tested) (PubMed:27801785).  Does not show antibacterial activity on both Gram-negative and Gram-positive bacteria (PubMed:27801785).  Intraperitoneal injection into fish provokes paralysis (By similarity).
What are the official names of this protein?
Conotoxin Asi3a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: S35B1_XENTR
Sequence: MAAGGAQGSGGARLLVCFLGVFVCYFYYGILQETITRGTYGEGEKQEKFRFALSLVFVQCIVNALFAKLLIQFFDSGKTDRTQSWLYAACSLSYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLRKKYPLSKYLCVLLIVLGVALFMYKPKNTGSGGDEHTFGYGELLLLLSLTLDGLTGVSQDHMRAHFQTGSNHMMLYINLWSSLFLGAGIVFTGELWDFLSFTERYPSIVYNIMLFSLTSALGQTFIFMTVVYFGPLTCSIITTTRKFFTILASVILFSNPISSIQWVGTILVFLGLGLDATYGKGSKKPSH
What is the function of this protein?
Probable sugar transporter.
What are the official names of this protein?
Solute carrier family 35 member B1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: BIOB_ACIB5
Sequence: MTLRNDWTREEIQALYEQPFLDLVFKAQQVHREHFTANTIQVSTLLSIKTGKCPEDCKYCSQSAHYDSKLEAEKRIAVEKVISEAKAAKDSGSSRFCMGAAWRNPHERDMPYVLEMVREVKALGMETCMTLGMLNQSQAERLKDAGLDYYNHNLDTSREYYSHIISTRTFDDRLNTLDYVRQAGMKVCSGGIVGLGESREDRIGLLHELATLPIHPESVPINMLVPIEGTPLADVEKLDVIEWIRTIAVARIIMPHSYIRLSAGRESLSDSDQALAFMAGANSLFSGDKLLTTPNAGEGKDQALFNKLGLTAEKPKPTVSDLSVDAMSA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RS3_TREPS
Sequence: MGQKVSPIGLRLGINKVWSSRWYAGPREYAALLHEDLRIRSMIRSFPECKNADIAEVEIVRHPQRVTVVMHTARPGVVIGAKGVNIEKIGAEVQKRLNKKVQIKVKEIKRMELNAYLVAQNVARQLTARVSFRKCLRQACAGTMKSGAQGVKIRVSGRLGGAEMSRTEEIKEGRTPLHTLRADIDYGFAEAHTTYGSIGVKVWLYSGMMYGNECRKDVGSLLRRSRRESGQKSDELVRDERTHAERG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TM266_MACFA
Sequence: MALAASFNMTNPQPAIEGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTAGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPVKLEMEMVIQQYEKAKVIQDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRFKVVEAGTWEEETAAESVVEELQPSQEAMVKDDMNSYISQYYNGPSSDSGVPDAAVCMVTTAAIDIHQPDISSDLFSLDMPLKLGGNGTGATSESASRSSVTRAQSDSSQTLGSSTDCSTAREEPSSEPGPSPLPLPPQQQVEEATVQDLLSSLSEDPCPSQRALDPAPLSRPSPAGSAQTSPELEHRVSLFNQKNQEGFTVFQIRPVIHFQPTVPVLEDKFRSLESKEQKLHRVPEA
What is the function of this protein?
Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum.  Despite the presence of a voltage-sensor segment, does not form a functional ion channel and its precise role remains unclear.  Undergoes both rapid and slow structural rearrangements in response to changes in voltage.  Contains a zinc-binding site that can regulate the slow conformational transition.
What are the official names of this protein?
Transmembrane protein 266.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Perikaryon. Note=Present in the dendrites and soma of cerebellar granule neurons, but not in their axon.