PharMolix/UniProtQA huggingface dataset:
Protein: DAPE_POLNA
Sequence: MSRTLHLAEQLISRPSVTPDDAGCQALLIARLAPLGFKCETIVSGPEHFRVTNLWAKFEGFSPSAQAALAQPAIESIANTELSQAKVKTLVFAGHTDVVPTGPLAQWHSHPFTPSHRAGKLYGRGTADMKTSIAAMVVAVEEFLAAHPRPALSMAFLITSDEEGPGIDGTVVVCDRLLARGEVLDYCIVGEPTSVKQLGDMIKNGRRGTLSGKLSVKGVQGHIAYPHLAKNPIHLFAPALAELVATQWDQGNDFFPATSWQVSNIHAGTGASNVIPGDLVVDFNFRFCTESTPESLQQRLLAILSKHQFEYELKWTLGGLPFLTTPGTLVDAVRGAILAETGVQTELSTTGGTSDGRFIAKICPQVIELGPVNATIHQINECVDTASLDPLKNIYKGVLERLAGLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CBIM_CLODR
Sequence: MKQNIKLGVIAALMLIVLTPVTSNAMHIMEGYLPVKWSIAWGVIFIPFFLVGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGAIMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIISFLIFKALKKKDGNNAMPVFLAAAIGDLATYTVTSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAEGILTVIVYNLITENGEKSILENNDKGVKANEC
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiM, Energy-coupling factor transporter probable substrate-capture protein CbiM, ECF transporter S component CbiM.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYK_GRAFK
Sequence: MHKKNYMQQLSEQEQIRRDKLTAIRKAGINPYPADLFPVDHTTTGIKENFEEGKNVVIAGRLMSRRIQGKASFAELQDSKGRIQVYFNRDEICTGEDKSKYNDLYKKLLDIGDFIGIEGELFKTQVGEMTVMVKDFHLLSKALRPLPLPKTDKEGNTHDGFNDPEQRYRQRYADLAVNPKVKEIFVKRTKLFNAMRNFFNEREYFEVETPILQSIPGGAAARPFVTHHNALDIPLYLRIANELYLKRLIVGGFDGVYEFSKNFRNEGMDRTHNPEFTAMEIYVAYKDYNWMMEFTEQLLEHCAEAVNGTTDATFGEHKINFKAPYKRLSMTDAIIEYTGFDITGKSEKELYEAAKGMDIEVDDTMGKGKLIDEIFGEKCEGKFIQPTFITDYPKEMSPLCKEHRDNPELTERFELMVCGKEIANAYSELNDPLDQRERFEEQLKLSEKGDDEAMFIDNDFLRSLEYGMPPTSGLGIGMDRLIMFLTNKQSIQEVLFFPQMKPEKKAVELSEEEKEVFKLLKNDSVHELNDIKEQSGLSNKKWDKAVKGLRKHKMIDVFKEGETLNMKIS
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF3C_SARS2
Sequence: MLLLQILFALLQRYRYKPHSLSDGLLLALHFLLFFRALPKS
What is the function of this protein?
May play a role in host modulation.
What are the official names of this protein?
ORF3c protein, ORF3c, ORF3h protein, ORF3h.
Protein: RK36_ORYSJ
Sequence: MKIRASVRKICTKCRLIRRRGRIRVICSNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MGSA_BREBN
Sequence: MKIALIAHDRMKEQIVQLAMAYESILAKHDLYATGTTGSRIMEATSLSLTRFLSGPLGGDQQIGAMIARNEMDLIIFLRDPLTSQPHEPDIIALLRLCDVHKIPFATNLGSAEIMLKALELGQLDWREVVREENEA
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RL21_BURM1
Sequence: MYAVIKTGGKQYKVAVGEKLKVEQIPADIDAEITLDQVLAVGEGESIKFGTPLVSGASVKATVVSHGRHAKVTIFKMRRRKHYQKHGGHRQNYTELRIDAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: VIF_HV2SB
Sequence: MDQGKRWIAVPTWRVPGRMEKWHSLIKYLKYRTKDLEQVRYVPHHKVGWAWWTCSRVIFPLKGNSHLEIQAYWNLTPEKGWLSSYSVRMTWYSEGFWTDVTPDCADTLIHSTYFSCFTAGEVRRAIRGEKSLSCCNYPQAHKSKVPSLQFLALVVVQQNDKPQRDNTTRKQWRRNYRRGLRLARQDGRSHKQRGSEPPAQGAYFPGVAKVLEILA
What is the function of this protein?
Counteracts the innate antiviral activity of APOBEC3G.  Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions.  Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery.  Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1.  Binds viral RNA and affects the stability of viral nucleoprotein core.  May play a role in viral morphology (By similarity).
What are the official names of this protein?
Virion infectivity factor, Vif, Q protein, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor (By similarity).
Protein: LOVG_CAEBR
Sequence: MSSQPKLRILCLHGYRQCDQSFRQKTGSTRKLVKALADFEFVNGIHSVAVDEHSETSRAWWFSNADQMSFSSREPTDVSVGFDESVNAVVKFIEDNGPFDGLLGFSQGASMVHLLIAKAQLGEIKLPGIRFAIFFSGFLSLSSKHDTLTSLRIKDFPSMHVFGDSDEIVARPKSEKLADQFDMEPIRIAHEGGHLVPSMSKHKERITQFLREQMAPIASA
What are the official names of this protein?
Esterase CBG03338.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: GAG_HV1H2
Sequence: MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEIKDTKEALDKIEEEQNKSKKKAQQAAADTGHSNQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRNQRKIVKCFNCGKEGHTARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSYKGRPGNFLQSRPEPTAPPEESFRSGVETTTPPQKQEPIDKELYPLTSLRSLFGNDPSSQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid- anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid- anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: SPLB_STAAC
Sequence: MNKNVVIKSLAALTILTSVTGIGTTLVEEVQQTAKAENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
What is the function of this protein?
Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln.
What are the official names of this protein?
Serine protease SplB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: Z379_ENCCU
Sequence: MIFRCCFEGCGKSFPRRAKLSDHLNTHTRSRPYKCDMCEKSYMKNGHLSVHKKKHFPPELACERCGYMCHTRDRLHKHQKACLEYKCGICGKRYRKRSWFDVHVESHHVKVFNAPRSKHVCEYCKFEFNKKSNLSTHVRSVHLLMKPFKCPCGKEYAHNASLDRHRKKCASWSYPGLDVAKPPAASNSLL
What are the official names of this protein?
Zinc finger C2H2 protein ECU03_0790.
Protein: PSAK_NOSP7
Sequence: MFTSTLLAAATTPLQWSPTVGLIIIIANIIAIAFGKSTIKYPNAEPALPSSNLFGGFGLPALLATTAFGHILGVGAVLGLHNLGRI
What are the official names of this protein?
Photosystem I reaction center subunit PsaK, Photosystem I subunit X.
What is the protein family that this protein belongs to?
Belongs to the PsaG/PsaK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RLMH_MESM1
Sequence: MKINLIAVGKLEKEYLNLYLSYLKKISFFATINLIEIKEINEKNIDLKKQKETELIIEKIPKNSKVYLCSLQGQEKTSEDFSLLFNEDNLTFVIGGSNGVDESTFLHKISFSKNTFPHQLFRILLVEQIYRSFTILKGIKYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
Protein: ZAPD_BURCH
Sequence: MILYEYPFNERIRTLLRLEDLFERFAFFLAQEDPREHHVALTTLFEIAEVTGRADLKSDLMKELERQRQTLAPFRGNPGIEQNALEAVLGEIEQTLANLAQMQGKTGQHLVDNEWLASIRSRAVIPGGTCKFDLPSYYAWQQWPAEQRRQDIAKWMLPMLPLRDAAAIVLRLARESGQASKVMAMQGSYQQMLSGRSYQLMQVRVPPELRVIPEASANKYMLWVRFTMQDGDVRPRAVDIDVPFHLTLCNL
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: KDGD_XANCB
Sequence: MSSRYTPSEMAQALGAGLLSFPVTHFDADMAFDEPAYRSNLDWLSSHPAAGLFAAGGTGELFSLTLDEVDRAVRAAVTQTAGRMPVIAPAGYGTAIAVAMAQAAERNDADGILLFPPYLTECDADGVAEHVERVCKATSLGVIVYGRANARLDDVALARVAERCPNLVGYKDGIGDVERMTRIYARLGDRLLYVGGLPTAETFALPYLEMGVTTYSSAIFNFLPEWALSFYAAVRARDHATIYRELNDFVLPYTVLRNRRAGYAVSIVKAGMRAVGRPAGPVRTPLADLTEDEFAQLTQLIGGRR
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: GLN1A_BACCE
Sequence: MARYTKEDIFRLAKEENVKYIRLQFTDLLGVIKNVEIPVSQLTKALDNKMMFDGSSIEGFVRIEESDMYLYPDLDTWVIFPWTAEKGKVARLICDIYNADGTPFEGDPRNNLKRVLKEMEALGFSDFNLGPEPEFFLFKVDEKGNPTLELNDNGGYFDLAPMDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYANAIRSCDDIQTFKLVVKTIARKHGLHATFMPKPLYGVNGSGMHCNLSLFKNGENVFYDQNGDLQLSDDARHFIAGILKHAPAFTAVANPTVNSYKRLVPGYEAPCYVAWSAQNRSPLVRIPASRGISTRVEVRSVDPAANPYLVMATLLAAGLDGIKNKLTPPAAVDRNIYVMTKEEREEAGIVDLPATLAQALVTLQSNEVISNALGDHLLEHFIEAKEFEWDIFRTQVHQWERDQYMSLY
What is the function of this protein?
Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism.  It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.  Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA.  During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation.  Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity.  In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3A_ASPNG
Sequence: MPAYNIVVFAGDHWGPEVTAEAIKVLRVIEKSRDDITLNLQDHLLGGASIDATANPLTDEALAAAKNADAVLLGAIGGPKWGTGAVRPEQGLLNVRKEMGTFGNLRPCNFAAPSLVEHSPLKASVCEGVDFNIIRELTGGIYFGDRKKMTAAATMDTEPYSRAEIERITPRAHLALQHNPPLPVWSLDKANVLATSRLWRKTVTEIMAKEFPQLKIEHQLIDSAAMIMVKNPRQLNGIIVTSNLFGDIISDEASVIPGSLGLLPSASLSGIPDGKGRVNGIYEPIHGSAPDIAGKGIVNPVAAILSVAMMMQYSFGRFDEARAIEAAVRNVLESGVRTGDIGGKATTSEVGDAVAAELEKLLK
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase A, 3-IPM-DH A, IMDH A, Beta-IPM dehydrogenase A.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPAT_NOSP7
Sequence: MATINNNYLKLKAGYLFPEISRRVNAFAEANPDAKIIRLGIGDVTEPLPEACRTAMIKAVEDMGDRNTFKGYGPEQGYAWLREKIAAQDFQARGANIDASEIFISDGSKCDTGNILEIFGHDNLIAVTDPVYPVYVDTNVMVGNTGDANDKGEFEGLVYLPITADNNFTAEIPSKKVDLIYLCFPNNPTGATATKEYLKAWVDYAKANNSIIFFDAAYEAYITDPSIPHSIYEIEGAREVAIEFRSFSKNAGFTGTRCALTVVPKTLTGKAADGSDVELWKLWNRRQSTKFNGVSYIVQRGAEAVYSEEGQAQIKGLVSFYLENAKIIREKLTAAGLSVYGGVNAPYVWVKTPNGLSSWEFFDKLLQTVNVVGTPGSGFGAAGEGYFRISAFNSRENVEEAMKRITKKFKV
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: GVPA_BRASO
Sequence: MAIEKSIASSSIAEVIDRVLDKGVVIDAFVRVALVGIELIAIEARVVIASVETWLKYAEAIGLTAQPSAA
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.  GvpA type proteins form the essential core of the structure.
What are the official names of this protein?
Gas vesicle structural protein, GVP.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane.
Protein: DIRA2_MOUSE
Sequence: MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM
What is the function of this protein?
Displays low GTPase activity and exists predominantly in the GTP-bound form.
What are the official names of this protein?
GTP-binding protein Di-Ras2, Distinct subgroup of the Ras family member 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Di-Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RL15_AGARV
Sequence: MDLSNLKAAEGSVHSDNFRRGRGHGSGNGKTAGKGHKGQKARSGAPRPGFEGGQMPLYRRLPKRGFKNRNTLTIVPINLSALERFDNDAVVSVETLIEAGIVKNPRDGVKILGNGELTKKLTVQANAFSASAKEKIEALGGKAEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: IXTPA_SYNY3
Sequence: MPTLIVATGNPGKLAEMQTYLEPLGCQLTLKPTEIEVEETGSTFYENACLKASQVAKAVNQWAIADDSGLAVDALDGAPGLYSARYGNTDRERIAKLLQALEGVSQRQAQFICVVSIAAPDGSIQLSTKGICSGEITHSPRGDQGFGYDPIFWLPEHKKTFAEMTKVEKQKVSHRGKAFNKLIHQWPGLKFDSF
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: UL76_HCMVA
Sequence: MPSGRGDDADSTGNALRRLPHVRKRIGKRKHLDIYRRLLRVFPSFVALNRLLGGLFPPELQKYRRRLFIEVRLSRRIPDCVLVFLPPDSGSRGIVYCYVIEFKTTYSDADDQSVRWHATHSLQYAEGLRQLKGALVDFDFLRLPRGGGQVWSVVPSLVFFQQKADRPSFYRAFRSGRFDLCTDSVLDYLGRRQDESVAHLLAATRRRLLRTARGKRAALPRARASAVAGGRGGDNARRGLARGRAHGPGAQTVSASGAQGSGSQGADLLRGSRRARVRGGGAVEPAVRARRRTVAADAATTTVSSAFFVPRDRRGRSFCRPTRSL
What is the function of this protein?
May participate in nuclear egress of viral particles.  Plays a role in the dispersal of several host nucleolar proteins including NCL/nucleolin and NPM1.  Since deletion of host NCL/nucleolin negatively impact on nuclear egress, UL76 supposedly acts on this process through its effect on host nucleoli.  Induces cell cycle arrest in host cells at the G2/M phase following by apoptosis.  The mechanism involves the inhibition of host mitotic complex cyclinB/CDK1.
What are the official names of this protein?
Protein UL76.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL24 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host nucleus, host nucleolus.
Protein: SEC20_RAT
Sequence: MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSELTELNTKVKEKFQQLKHRIQELEQSAKEQDKESEKQLLLQEVENHKKQMLSNQTSWRKANLTCKLAIDNLEKAELLQGGDSLRQRKTTKESLAQTSSTITESLMGISRMMSQQVQQSEEAMQTLVSSSRTLLDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL
What is the function of this protein?
As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization.  Also plays a role in apoptosis.  It is for instance required for endoplasmic reticulum stress-induced apoptosis.  As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy.
What are the official names of this protein?
Vesicle transport protein SEC20.
What is the protein family that this protein belongs to?
Belongs to the SEC20 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Mitochondrion membrane; Single-pass type IV membrane protein. Note=Localization to the mitochondrion is regulated by RNF186.
Protein: ZEB1_MAIZE
Sequence: MKMVIVLVVWLALSAASASAMQMPCPCAGLQGLYGAGAGLTTMMGAGGLYPYAEYLRQPQCSPLAAAPYYAGCGQTSAMYQPLRQQCCQQQMRMMDVQSVAQQLQMMMQLERAATASSSLYEPALMQQQQQLLAAQGLNPMAMMMAQNMPAMGGLYQYQYQLPSYRTNPCGVSAAIPPYY
What is the function of this protein?
Zeins are major seed storage proteins.
What are the official names of this protein?
Zein-beta, 16 kDa zein, Zein clone 15A3, Zein-2.
What are the subcellular locations of this protein?
Vacuole, aleurone grain. Note=Endosperm protein bodies.
Protein: DXR_CAMJD
Sequence: MILFGSTGSIGVNALKLAALKNIPISALACGDNIALLNEQIARFKPQFVAIKDSKNKHLVKHDRVFIGQEGLEQILTECQDRLLLNAIVGFAGLKSTLKAKELGKNIALANKESLVVAGSFLKGAKFLPIDSEHVALKFLLEGKKNIAKLYITASGGAFYKYKIKDLNQVSVKDALKHPNWNMGAKITIDSATMANKLFEIIEAYHLYDFKESDALIEPRSLVHAMCEFKNGASTAYFSKADMKLAISDAIFEKQDTPILEAVDFSKMPALKFHKISTKKYPIFKLKNAFLKEPNLGVIINAANEVGVYNFLENKSGFLDIAQCIFKALDHFGAPKISSIEEVFEYDFKTREYLRS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MPPA_SCHPO
Sequence: MSFLTTPKMLSEYQCLKNIGFSHKTVLKRRLFRKECTPALKSFYSTQDPALNEVRTEKLKNGVTYVCDPRPGHFSGLGVYVKAGSRYETKKFSGVSHFMDRLAFQATERTPVGEMKAKLENLGGNYMCSTSRESMIYQAAVFNDDVKSMSKLLAETVLAPKIQEDDLVHYRDSIIYENSELWTKPDALLGEFAHVTAFQNNTLGNCLLCTPDKVNGITATSIREYLKYFYRPEHLTLAYAGIPQEIAKEITKELYGHLPSSSLPPLEAIPSHYTGGFMGIKKSEAPPVPYQQEFTHVVIAMEGLPVTDPDIYALACLQFLLGGGGSFSAGGPGKGMYSRLYLNVLNQYPWVETCMAFNHSYTDSGLFGMFVTILDDAAHLAAPLIIRELCNTVLSVTSEETERAKNQLKSSLLMNLESRMISLEDLGRQIQTQNGLYITPKEMIEKIDALTPSDLSRVARRVLTGNVSNPGNGTGKPTVLIHGNVDEVGDVFALCKKAGIGH
What is the function of this protein?
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
What are the official names of this protein?
Probable mitochondrial-processing peptidase subunit alpha, Alpha-MPP, Inactive zinc metalloprotease alpha.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
Protein: Y3835_MYCTO
Sequence: MLDAPEQDPVDPGDPASPPHGEAEQPLPGPRWPRALRASATRRALLLTALGGLLIAGLVTAIPAVGRAPERLAGYIASNPVPSTGAKINASFNRVASGDCLMWPDGTPESAAIVSCADEHRFEVAESIDMRTFPGMEYGQNAAPPSPARIQQISEEQCEAAVRRYLGTKFDPNSKFTISMLWPGDRAWRQAGERRMLCGLQSPGPNNQQLAFKGKVADIDQSKVWPAGTCLGIDATTNQPIDVPVDCAAPHAMEVSGTVNLAERFPDALPSEPEQDGFIKDACTRMTDAYLAPLKLRTTTLTLIYPTLTLPSWSAGSRVVACSIGATLGNGGWATLVNSAKGALLINGQPPVPPPDIPEERLNLPPIPLQLPTPRPAPPAQQLPSTPPGTQHLPAQQPVVTPTRPPESHAPASAAPAETQPPPPDAGAPPATQSPEATPPGPAEPAPAG
What is the function of this protein?
May play a role in septum formation.
What are the official names of this protein?
Uncharacterized membrane protein MT3943.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Secreted.
Protein: ALAXM_PYRHO
Sequence: MINMTRKLYYEDAYLKEAKGRVLEIRDNAILLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDEEGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGNWQLVGSGMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKIWWEGDRRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWLE
What is the function of this protein?
Functions in trans to edit the amino acid moiety from mischarged charged Gly-tRNA(Ala) and Ser-tRNA(Ala).
What are the official names of this protein?
Alanyl-tRNA editing protein AlaX-M, AlaX-M, Alanyl-tRNA deacylase AlaX-M.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Editing domain AlaX-M subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLOV_HYACE
Sequence: DVTWDKNIGNGKVFGTLGQNDDGLFGKAGFKQQFFNDDRGKFEGQAYGTRVLGPAGGTTNFGGRLDWSDKNANAALDISKQIGGRPNLSASGAGVWDFDKNTRLSAGGSLSTMGRGKPDVGVHAQFQHDF
What is the function of this protein?
Antibacterial protein active against Gram-negative bacteria.
What are the official names of this protein?
Gloverin.
What are the subcellular locations of this protein?
Secreted.
Protein: F16A2_ACAM1
Sequence: MSHPTTFNSHLWQQHRLAQQPIEISILLTQMGFAAKVLAREISRAALMGNLGLMGETNATGDAQKKLDVFSNQIVIDAFSNIGLVAVIASEELDQVKLIECGQQAQYILCTDPLDGSSNTDTGSAVGTIFGIYRRQTSGYCSTEADVLQPGTELVTAGYVLYGTSTMLVYTTGGRVDGFTLDPSLGEFLLSHENIRCPETGKTYSANLSYYQEWHPHIQNFADYLSDRKSHTAHTLRYSGALVADVHRCLLEGGLYFYPPTADQPEGKLRLLYECAPLAFLVEQAGGKATSGLARIMDLEVTSIHQRSPLVIGSQVAVNLYQTFLEQGKAA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 2, FBPase class 1 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.