PharMolix/UniProtQA huggingface dataset:
Protein: RPGP2_CHICK
Sequence: MFQRKRSVSFGGYGWIDKTMLASLKMKKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTDIKNRNSPRSNLKFRFDKLSHGSSSTSH
What is the function of this protein?
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.
What are the official names of this protein?
Rap1 GTPase-activating protein 2, Rap1GAP2, GTPase-activating Rap/Ran-GAP domain-like protein 4.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IP5P8_ARATH
Sequence: MGKILKSKSSWPRTVVRKWLNLRSGAYEFHSDYPVKGMEPRRKSCSDMIVPENFQGWLGQGNGDLKHSTGEQHVTRVDDKLDLKMFVGTWNVGGKSPHEGLDLKDWLKSPADADIYVLGFQEIVPLNAGNVLGAEDNGPAAKWLSLIREALNNTNNLSPNELEHTKSSQQPRFSFSGLSDDTPIPCNSTPPRGYSLAASKQMVGIFLCVWVRDDLRKRITNLKVSCVGRGIMGYLGNKGSVSISMSLHETSLCFVCTHLTSGEKEGDELRRNLDVTEIFKRTRFSRSSKDSRPETIMDHDKVIWLGDLNYRLRASSDLHEQLRNHDWESLLEKDQLKIEQRAGRIFKGWEEGKIYFAPTYKYRINSDNYVVQTEKSKEKRRTPAWCDRILWKGDGMKQLWYVRGESKFSDHRPVQSLFSVHIDLKNQSNRKTKPVNQNHRPNPVLTYTCHGKVQAEEILLLTRAQSCIDTLPRLISSAS
What are the official names of this protein?
Type I inositol polyphosphate 5-phosphatase 8, At5PTase8.
What is the protein family that this protein belongs to?
Belongs to the inositol polyphosphate 5-phosphatase family.
Protein: GPH_KLEAE
Sequence: MDKLQAIRGIAFDLDGTLVDSAPGLTSAVDNALYALELPVAGEERVITWIGNGADVLMERALTWARQERATLRAAMGKPSVDDHDIPQDEQLRILRKLFDRYYAEAAEEGSFLFPAVADTLGALHAKGLPLALITNKPTPFVAPLLDALDIAKYFTVVIGGDDVQNKKPHPEPLLLVAEKLSLAPAELLFVGDSRNDIQAAKAAGCCSVGLTYGYNYGEPLALSEPDYLFDQFNELLPALGLPHSETQELKHD
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: MA162_PINFU
Sequence: MKCTLRWTITALVLLGICHLARPAYHKKCGRYSYCWIPYDIERDRRDNGGKKCCFCRNAWSPWQCKEDERYEWLRCGHKFYYMCCYTDDDNGNGDGNGNGFNYLKSLYGGYGNGNGEFWEEYIDERYDK
What is the function of this protein?
May be specifically involved in the formation of the nacreous layer.
What are the official names of this protein?
N16.2 matrix protein, N14#2.
What is the protein family that this protein belongs to?
Belongs to the N16 matrix protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MNMA_STAAC
Sequence: MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKSEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPE_SALEP
Sequence: MEQFECITVEEAYQKLHQGAAVLVDIRDPQSYAMGHAPQAFHLTNDTLGAFMREHGFDTAVMVMCYHGNSSKGAAQYLLQQGYDAVYSIDGGFEAWHRRFPADVANGA
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHH_PROMS
Sequence: MAQLETRTEPMVVNFGPHHPSMHGVLRLVVTLDGENVIDCEPVIGYLHRGMEKIAENRTNVMYVPYVSRMDYAAGMFYEAIVVNAPERLANIPVPKRASYIRVLMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGQRLINNNFFRIGGVACDLPYGWLEKCIDFCDWFGPKIDEYEKLITNNPIFKKRIEGLGTIQRDQAINWSLSGPMLRASGVSWDLRKVDSYECYDDFDWQIASEKEGDCYARYRVRVEEMRQSLSIIRQACKMIPGGPTENLEAQRMVTEDKKSEIFGIDYQYVAKKVAPTFKIPNGELYTRLESGKGEIGVFIQGNNEVTPWRFKIRAADLNNLQILPHILKGAKIADIMAILGSIDVIMGSVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase subunit H, NDH-1 subunit H, NDH-H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACCA_STAA9
Sequence: MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDVEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAT_BACAN
Sequence: MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPKIINALIDQANRVTLTSRAFHSDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRWAYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRGFGPMLPGIIVIPYGDLEALKAAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFACDWDNVTPDMYILGKALGGGVFPISCAAANRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTERSLQLGEKLVGQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase, OAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT222_ASPTN
Sequence: MQDDEITENIQPPPQYPGDDTRPTSKKELVGWYSYGWAAEVFTVCAMGSFLPITLEQMARDSGVLLADKTTPCSATWKTPQGTSPTLSADTTGLWSSQAPRTSQCIVHILGAEINTASFAMYTFSVSVFVQAILIISMSGAADHGSYRKILLVACALIGSISTMMFIAVKPNLYILGGLFAVVANTCFGASFVLLNSFLPLLVRHHPSLLAKHRQAGASPNGDRPPATHRAHRTEDEVNVTTPLLPSGSTNTDGATQESVSDTSLELKLSTKISSNGIGIGYIAAVILQIICIVVVVNTNQTTFSLRLVLFLIGLWWFIFTFPAALWLRPRPGPPLRYADGGKERRSWLGYIAYAWKSLGRTAMRTRHLKDILLFLASWFLLSDGIATVSGTAVLFAKTQLDMEPAALGMINVIAMMAGVFGAFSWSYVSRVLNLRASQTIIACIILFELVPIYGLLGFIPAIKRLGFIGLQQPWEMYPLSFVYGLVMGGLSSYCRSFFGELIPPGYEAAFYALYAITDKGSSIFGPAIVGAITDRYGEIRPAFGFLAILILLPLPLMLLVDVDRGKRDAQALSAELEGTRDEPVADGSLE
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22-2.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: H2A_ASPTN
Sequence: MTGGKSGGKASGSKNAQSRSSKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKTPKAKGSQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: UNG_XANOR
Sequence: MTEVEARIQLEPSWKAKVGDWLLCSQMQELSAFLRQRKAVGARVFPPGPQIFAAFDATPFDQVKVVILGQDPYHGEGQAHGLCFSVLPGVPVPPSLLNIYKEIQDDLGIARPDHGYLMPWARQGVLLLNAVLTVEQGRAGAHQNKGWEGFTDHVVETLNREREGLVFLLWGSYAQSKGRVIDQARHRVFKAPHPSPLSAHRGFLGCQHFSKTNAHLQRRGISPIDWSLPPRNELDTTSAGA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TR107_MOUSE
Sequence: MLNSAEGILLCVVTSEAVLGVLGDTYIALFNCMDYAKNKKLSKIGFILIGLAISRIGVVWIIILQGYIQVFFPHMLTSGNITEYITYIWVFLNHLSVWFVTNLNILYFLKIANFSNSVFLWLKRRVNAVFIFLSGCLLTSWLLCFPQMTKILQNSKMHQRNTSWVHQRKNYFLINQSVTNLGIFFFIIVSLITCFLLIVFLWRHVRQMHSDVSGFRDHSTKVHVKAMKFLISFMVFFILHFVGLSIEVLCFILPQNKLLFITGLTATCLYPCGHSIIVILGNKQLKQASLKALQQLKCCETKGNFRVK
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 107, T2R107, mT2R43, STC5-1, T2R4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MED16_CANGA
Sequence: MCELNNKRVSWSKTGLIAYADEQSTYGNLCISFLETINGVNCRFHPPQRYVIHPQLHEVPLKTETGNGINGASGSSTAQSNIHGTTSVPGSAGKHQHQFFYDISSIHWNNWFSLPGDMLAVCDELGNMTMLIAGQSPDGPTTLDKLTMLFQDNVYKIHNHVMQLEPERENTDSKLERKKTKKEYNTTILDFHWLSSSKPVIVSQFCAFDSSINMYRNKAQQLSPHGIFHPPFMKYAGLAIRRNGQLDFWYQFSNSKDHKKITLQLFNPHNERSKGLDFLQYAKITSVNNDNSILITTYSRLTGKLSFYKLFVDWNVNTAKPVVLNDPSLKIKHILDATVDQTDDEGRILDFTHVHVLAKVVAEKDAAPEVLLAYDVVGTPESLIKRFKLGQVRLPLDYLGILKPELNTSNENHNQALRSNRSNLRFLGVLNLHHKVASISSEVLDGFVSFYYRNGEIEIYNQNDWKLETERLLNQGPQGKFSNIITSILSAGFKYPTIKNLGTVEWIRVSPAMAGILYKYRHDDLPQFQPMNIDDVSDKSKDEINAATMAFGYVTSAHRQLSGEDIALACKQHILKIAKIDEKRAKDFTTTLMFNLYNFFNFSPGAPKELMDKIISSRPLQKVMLLQLELGSIFTDENTCEMARVILYLKNVSFAFNGVARNLQFAIEQMTNSTNSSNPPLSGDKFFQTAFSKQDLVHSLIPVTKWFVKFITYLIQQILILTNDPENPDNRLVLGVFGAKIPRTLILTILKEIKNVTAIITKFPETNYPILNESSTYLKMLLIESPINFEKFETFLMDVNNKLSAFSEQQPSIMREPTLLVRSSVPNELNKITEFLLQYSSNTVISHADASAIYFSDTSGLRISCDEFFEPGVHRLLQPIEDGIVIDEKNMPATFRDSKTFTKLTYDGITYDRFSKEELSDNKLKRCNRCGAVTKAGYPIPTNKTIVPTSISTRRWPTMYTRMCICLGMLYEL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 16, Mediator complex subunit 16.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LGUL_HUMAN
Sequence: MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:9705294, PubMed:23122816).  Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (PubMed:19199007).  Required for normal osteoclastogenesis (By similarity).
What are the official names of this protein?
Lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: PGK_SHEFN
Sequence: MAIINMTDLDLQNKRVLIREDLNVPVSDGVVTSDARLRASLPTIQLALKKGAAVMVMSHLGRPTEGEFNAEYSMQPVVDYLAKALDCPVRLVSDYLDGVDVNVGEVVVFENVRFNVGEGKNDEALSKKMAALCDVYVMDAFGTAHRAQASTHGVGVYAPIACAGPLLSQELDALGKALDNPARPMVAIVGGSKVSTKLTVLESLSTKVDQLVVGGGIANTFIAAAGYKVGKSLYEADLVEEAKRLVANARSRGGDIPVPTDVVVASEFSPTAAATLKSVADVTDSDMIFDIGPDSAEALAKIIEQAGTIVWNGPVGVFEFDQFGEGTKRIAQAIANSKAFSIAGGGDTLAAVDKYNIADKVSYISTGGGAFLEFLEGKELPAVAMLEKRGA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_ACET2
Sequence: MTCVKICGLRRKEDIDYVNLYKPQFAGFVFAESRRKVSKETARMLVKALLPQIKSVGIFVNEKKETVAEIVKYTGLDCVQLHGDETPEYVEKLKELLGRITEKRIEIWKAVRVKNKESLEIISEFDVDAFLLDAYVEGSYGGAGAVFDWQLAADVAAGHERIILAGGLNPENVKTAVAKVKPYGVDVSSGVETDGFKDAEKIRDFIMKVREADGGVLS
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: ATPA_CAMFF
Sequence: MSVKLKADEISSIIKERIENYNLSVDIEETGKVISVADGVANVYGLKNVMAGEMVEFETGEKGMALNLEESSVGIVVLGKSSSIKEGSSVKRLGKLLRVPVGDALIGRVVNALGEPIDAKGAIEATETRFIEEKAKGIMARKSVHEPLQTGIKAIDGLVPIGRGQRELIIGDRQTGKTTVAIDTIINQKGQDVICIYVAIGQKQSTVAQVVKKLEEYGAMDYTIVVNASASDAPALQYLAPYAGVTMGEYFRDNSRHALIIYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLERASKLSDKLGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESDLFNSGIRPAINVGLSVSRVGGSAQIKAIKKVSGTLRLDLAQYRELQAFAQFASDLDESSRKQLERGQRMVEVLKQPPYSPLPVENQVIIIYAGSQGYLDDIPVSAVTKFEAELYPYIEAKYPEIFEQIRNKKALDKDIEEALSKALNEFKATFSAE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NP7_RHOPR
Sequence: MELYTALLAVTILSPSSIVGLPGECSVNVIPKKNLDKAKFFSGTWYETHYLDMDPQATEKFCFSFAPRESGGTVKEALYHFNVDSKVSFYNTGTGPLESNGAKYTAKFNTVDKKGKEIKPADEKYSYTVTVIEAAKQSALIHICLQEDGKDIGDLYSVLNRNKNALPNKKIKKALNKVSLVLTKFVVTKDLDCKYDDKFLSSWQK
What is the function of this protein?
Converts nitrite as the sole substrate to form nitric oxide gas (NO).  NO(2-) serves both as an electron donor and as an electron acceptor.  Binds to negatively charged cell surfaces of activated platelets; binds to L-a-phosphatidyl-L-serine (PS)-bearing phospholipid membranes.  Once bound on an activated platelet, NP7 releases its stored nitric oxide gas (NO) into the victim's tissues while feeding, resulting in vasodilation and inhibition of platelet aggregation.  Also acts as an anticoagulant by blocking coagulation-factor binding sites.  Has antihistamine activity; binds histamine with high affinity.
What are the official names of this protein?
Nitrophorin-7, NP7, Nitrite dismutase.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Nitrophorin family.
Protein: ATPL_RUMCH
Sequence: MAGTGIIAIAAAIAAFTGIGAGIGISLATGKAVEGIARQPEAAGSIRTSLLLGAALAEATAIYGLVVALVLVFLKM
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2001_MYCBO
Sequence: MVGPRTRGYAIHKLGFCSVVMLGINSIIGAGIFLTPGEVIGLAGPFAPMAYVLAGIFAGVVAIVFATAARYVRTNGASYAYTTAAFGRRIGIYVGVTHAITASIAWGVLASFFVSTLLRVAFPDKAWADAEQLFSVKTLTFLGFIGVLLAINLFGNRAIKWANGTSTVGKAFALSAFIVGGLWIITTQHVNNYATAWSAYSATPYSLLGVAEIGKGTFSSMALATIVALYAFTGFESIANAAEEMDAPDRNLPRAIPIAIFSVGAIYLLTLTVAMLLGSNKIAASGDTVKLAAAIGNATFRTIIVVGALISMFGINVAASFGAPRLWTALADSGVLPTRLSRKNQYDVPMVSFAITASLALAFPLALRFDNLHLTGLAVIARFVQFIIVPIALIALARSQAVEHAAVRRNAFTDKVLPLVAIVVSVGLAVSYDYRCIFLVRGGPNYFSIALIVITFIVVPAMAYLHYYRIIRRVGDRPSTR
What is the function of this protein?
Probable amino-acid or metabolite transport protein.
What are the official names of this protein?
Uncharacterized transporter Mb2001c.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GM_MUHVK
Sequence: MAKAGVMTLSHVDRMNLRTWTMAIACCLLSFVNIVVFSVAAHFPGIGFPCYYPRIIDFDNMNLTMYNAIHHLTPQLFLDPVQLIVYVIFTELIFFCVLSYYIVCWVQIYFRSEHGTQVNQSTRDINFMGDSATCFTFVLTMDTFQIFLLSLSFRLPSMVAFSKCMYFMCLTAFVVTLVTHYESRERSAFALSKIHPKLQGTIRYRTAVVNLTQLILGFATMVLAMSLALGFGNSFFVKTAHVVFGAMVAFAIVACVYFSIIESVLSRYMKVQFGYHIGTILGVCGAMYPIIRYEALNASSYARDINIGITVLLLLCVAFSVIRTVRFLLRRNKRYRALALDNEEIRALRSDAE
What is the function of this protein?
Envelope glycoprotein important for virion assembly and egress.  Plays a role in the correct incorporation of gH-gL into virion membrane.  Directs the glycoprotein N (gN) to the host trans-Golgi network.
What are the official names of this protein?
Envelope glycoprotein M, gM.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein M family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network. Host endosome membrane; Multi-pass membrane protein. Host nucleus inner membrane; Multi-pass membrane protein. Note=During virion morphogenesis, this protein accumulates in the trans-Golgi network where secondary envelopment occurs.
Protein: ACTP2_ACTEQ
Sequence: MSRLIIVFIVVTMICSATALPSKKIIDEDEEDEKRSADVAGAVIDGASLSFDILKTVLEALGNVKRKIAVGVDNESGKTWTALNTYFRSGTSDIVLPHKVPHGKALLYNGQKDRGPVATGAVGVLAYLMSDGNTLAVLFSVPYDYNWYSNWWNVRIYKGKRRADQRMYEELYYNLSPFRGDNGWHTRNLGYGLKSRGFMNSSGHAILEIHVSKA
What is the function of this protein?
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cardiac stimulation and cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers.  Cytolytic effects include red blood cells hemolysis, platelet aggregation and lysis, cytotoxic and cytostatic effects on fibroblasts.  Lethality in mammals has been ascribed to severe vasospasm of coronary vessels, cardiac arrhythmia, and inotropic effects.
What are the official names of this protein?
DELTA-actitoxin-Aeq1a, DELTA-AITX-Aeq1a, Equinatoxin II, EqT II, EqTII, Equinatoxin-2.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: ATG43_SCHPO
Sequence: MSSESKGIPIPRSDSNKTSDVSSWEEDYELISLGSSQDALQRSGIRSAHGDSGYASSPLRMEHLSSSTIIINNQLKKIDVNESIPENSTLHNKYELGAVESSTSSLSLLQSKEEDDSSNWETEDSESAVEEAELPTIFEGKTVISPSSSGTDHSEAVEYTVPTAPPIPDLRFQQSYLQSIQRANGSAFLVALITLRDHVLYPFLSGGMWVFVRHIFQFLKLQEKGFHFGQSLRRNLGLFSTFKD
What is the function of this protein?
Mitophagy receptor that tethers atg8 to the mitochondrial outer membrane to promote selective autophagy.
What are the official names of this protein?
Mitophagy receptor atg43.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Protein: PCRB_OCEIH
Sequence: MKNINEWHHIFKLDPAKEISDEHLDQICESGTDAIIVGGTDNVTLDGVLDLLSRIRRSHMVPVVLEVSEEETLTPGFDYYFVPMVLNSKEKKYMMDIQHKAIKEFIDMMEFAEVYFEGYCILNEDAKAFQYTNCVMPDLDDVKAYAYMAEKVFHLPFFYIEYSGAYGDPTLVKEVKEELQNTQLLYGGGIETTAQAKEMKEYADTIIVGNSIYTNINEALKTVEAVKGN
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: METN_LEGPL
Sequence: MIELCGLKKSFSGKLALNDINLFIQEGEVFGVIGKSGAGKSTLLRCINILEKPDEGEVVIDGQNLMSLSRKDLALARHKIAMIFQHFNLLNSKTVFDNIALPMRIQGIDEESIKQKIEELLPVVELTDKKDAFPSQLSGGQKQRVAIARALSCSPKVLLCDEATSALDPATTDAILSLLKKINELYGITIVLITHEMDVVKRICQRLSVMVDGKIVETTALSNIFNKPESLARKMLYAQISPELPTCLTRRLADYATEKPLVRLFFQGEEATVPFISQTSRELNMDINILLANIDRFDGVTCGVLVVELTANPLLLEAFINRCEQAGITVEVLGYVLPDGL
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS16_RHOPS
Sequence: MSVVIRLARAGTKKRPFYHVVVADSRFPRDGRFIERLGYFNPLMAKDNEARLKLDLDKVKDWLAKGAQPSDRVARFLDTAGIKKREARNNPEKAVPRKERKAAEAGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.