PharMolix/UniProtQA huggingface dataset:
Protein: NLPI_ECOLU
Sequence: MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDEKQAKEVLRQHFEKSDKEQWGWNIVEFYLGNISEQTLMERLKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALLELSLLGQDQDDLAESDQQ
What is the function of this protein?
May be involved in cell division.  May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity).
What are the official names of this protein?
Lipoprotein NlpI.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TOAP1_TITOB
Sequence: MQMKYLIPIFFLVLIVADHCHAFIGMIPGLIGGLISAFKGRRKRDITAQIEQYRNIQKREAAELEELLANLPVY
What is the function of this protein?
Antimicrobial peptide.  Is able to kill Mycobacterium abscessus subsp.  massiliense in a dose-dependent manner (By similarity).  Has antifungal activity against Candida spp.  and one Cryptococcus neoformans strains with MICs values ranging from 12. 5 to 200 uM (PubMed:27917162).  Also shows an inhibitory activity on C. albicans biofilms at high concentrations (PubMed:27917162).  Shows low cytotoxic activity and has weak hemolytic activity on human erythrocytes (PubMed:27917162).  Shows anti-inflammatory activities, since it decreases release of pro-inflammatory cytokines, and increases release of anti-inflammatory cytokines (By similarity).  Acts by blocking the Toll-like receptor 4 (TLR4) (By similarity).  In addition, decreases the expression of costimulatory molecules such as CD80 and CD86 in LPS-stimulated cells (By similarity).  In vivo, does not induce immune cell migration (By similarity).  Helical wheel projections predict an amphipathic peptide with distinct hydrophobic and hydrophilic faces (Probable).
What are the official names of this protein?
Antimicrobial peptide ToAp1.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ITI_FAGTA
Sequence: LIYAKVECLTTGVRTYVGKQSWPELVGTKGKTAAATIDKENTHVTAVLCPPLTTLAACRTFDFRCDRVRVLINRIGGVVTKTPTVG
What is the function of this protein?
Serine protease inhibitor which is active against trypsin.  Displays strong antifungal activity against a number of phytopathogenic fungi including M. melonis, A. cucumerina, A. solani, C. glaeosporioides and P. capsici.
What are the official names of this protein?
Trypsin inhibitor, FtTI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I13 (potato type I serine protease inhibitor) family.
Protein: GCSPB_STAES
Sequence: MISKSSPLIFERSKKDRYAYSLPQNDIENISIASLLDDKYIRKHKAEFPEVSELDLVRHYTELSNKNFGVDTGFYPLGSCTMKYNPKINEKVARISGFSESHPLQEEEHVQGSLEIIYSLQEELKEITGMDEVTLQPAAGAHGEWTALMIFKAYHEKNGQSHRDEVIVPDSAHGTNPASASFAGFKSVTVKSNQRGEVDIEDLKRVVNDNTAAIMLTNPNTLGIFEQNIIEIGKIVHEAGGLLYYDGANLNAILDKVRPGDMGFDAVHLNLHKTFTGPHGGGGPGSGPVGVVEKLASYLPKPMVIKDNDRYKYDNDIPNSIGRVKPFYGNFGIYLRAYTYIRSMGANGLKEVSEAAVLNANYIKSRLKNHFEIPFNQYCKHEFVLSGTLQKQYGVRTLDMAKRLLDFGVHPPTIYFPLNVEEGMMIEPTETESKETLDYFIDAMIQIADETKNDPDKVLEAPHTTIIDRLDETTAARKPILKFEELKDEKYKEHTNIDSEDN
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: RLMI_ALISL
Sequence: MTVSIYLVKGRDKALRRRHPWIFSRGIEKMDGKPQLGETVEIYSNSGEWLARGAFSPQSQIRARVWTFDKNEAIDKDFFVRKLNQAQGLRDILAEREGLTGYRLIAAESDGLPGITIDRYQNYFVCQLLSAGAEANKDQLVEALIECYPDCNIYERSDVSVRKKEGLKQRTGVLHGEEPPESVIIEENGVKISVDIVNGHKTGFYLDQRDSRERSCKYVKDKSVLNCFSYTGGFGLYALKGGAKHVINADVSQLALDNAKNNTEINGFDLSKAEFLNADVFKLLREYRDNGTKFDVVIMDPPKFAESKNQLVGACRGYKDINMLAMQILNPGGTLLTYSCSGLMDTGLFQKIVADAALDAKRTVQFIERFEQAADHPLDSAYPEGFYLKGFACRVI
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_GEODF
Sequence: MAKISRALISVSDKTGIVDFSKELAGYGVEILSTGGTAKLLREAGLAVKDVSEFTGFPEMLDGRVKTLHPKVHGGLLGMRGNSEHVATMKAHGIEPIDMVVVNLYPFEATVAKPDCSLEDAIENIDIGGPTMLRSAAKNNADVTVLVDHNDYRKVLDEMKQSGGAVSSATNFGLAVKVYQHTAAYDGAISNWLGARTGEGVAEYPDTLTFQFKKAQGMRYGENPHQSAAFYVERDVKEASIATALQLQGKELSYNNIGDTDAALECIKQFNEGPACVIVKHANPCGVAIGANLLDAYDRAYKTDPESAFGGIIAFNGELDEAAAKAIVDRQFVEVIIAPKVSAKASEIVAAKKNVRLLQCGQWQAESLARLDMKRVNGGLLVQQTDLSLHGELKVVTKRQPTEKEMIDLLFTWRVAKFVKSNAIVYGKDGMTIGVGAGQMSRVNSARIAAIKAEHAGLQVAGAVMASDAFFPFRDGIDNAAQVGITAVIQPGGSMRDEEVIAAADEHGMAMVFTSMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: CREC_ASPOR
Sequence: MAQGPSCASELHYYRALDHANAGFATGTYHLKDDLHLATPPPHPSEAPVVNPNPLATVPTPPTSGVKLSLVSVGQRNKLPVFTSKEKVTAPPFADGNPALAAIPTKDGLKRRKPKNNIIKSSSSFVSRVITHEASSKRLNDRNPDGLFAFANINRAFQWLDLSSKNKEEPLAKILFTKAHMLTHDINELTKSSSHIDIAMGSSAGDIIWYEPISQKYARINKNGVVSNSPVTHIKWIPGSENMFMAAHANGQLVVYDKEKEDALFTPEISNHSAEAMKASSRLPLQVLKSVNSRNQKTNPVALWKLANQKISQFAFSPDQRHLAVVLEDGSLRVMDYLKEEVLDIFRSYYGGLICVCWSPDGKYIVTGGQDDLVTIWSFPERKIVARCQGHNSWVSTVAFDPWRCDERTYRFGSVGDDCRLLLWDFSVGMLHRPRAHQASARQRTSMIASNTQHFNRHRADSASNRMRSDSQRTADTYNDYDSAVRHPVEPRARTALLPPIMSKIVGDDPICWLGFQEDSIMTSSLEGHIRTWDRPREGINDSYNGNTSSPAISTSAAGSGSGIADSAMGSL
What is the function of this protein?
Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression.  CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways (By similarity).
What are the official names of this protein?
Probable catabolite repression protein creC.
What is the protein family that this protein belongs to?
Belongs to the WD repeat creC family.
Protein: GSTUD_ARATH
Sequence: MAQNDTVKLIGSWSSPYSLRARVALHLKSVKYEYLDEPDVLKEKSELLLKSNPIHKKVPVLLHGDLSISESLNVVQYVDEAWPSVPSILPSDAYDRASARFWAQYIDDKCFAAVDAVVGAKDDEGKMAAVGKLMECLAILEETFQKSSKGLGFFGGETIGYLDIACSALLGPISVIEAFSGVKFLRQETTPGLIKWAERFRAHEAVKPYMPTVEEVVAFAKQKFNVQ
What is the function of this protein?
In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC).  May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase U13, AtGSTU13, GST class-tau member 13, Glutathione S-transferase 12.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Tau family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CP3A6_RABIT
Sequence: MDLIFSLETWVLLAASLVLLYLYGTSTHGLFKKMGIPGPTPLPFIGTILEYRKGIWDFDIECRKKYGKMWGLFDGRQPLMVITDPDMIKTVLVKECYSVFTNRRSFGPVGFMKKAVSISEDEDWKRVRTLLSPTFTSGKLKEMLPIIAQYGDVLVKNLRQEAEKGKPVDLKEIFGAYSMDVITGTSFGVNIDSLRNPQDPFVKNVRRLLKFSFFDPLLLSITLFPFLTPIFEALHISMFPKDVMDFLKTSVEKIKDDRLKDKQKRRVDFLQLMINSQNSKEIDSHKALDDIEVVAQSIIILFAGYETTSSTLSFIMHLLATHPDVQQKLQEEIDTLLPNKELATYDTLVKMEYLDMVVNETLRLYPIAGRLERVCKKDVDINGTFIPKGTIVMMPTYALHRDPQHWTEPDEFRPERFSKKNKDNINPYIYHPFGAGPRNCLGMRFALMNIKLALVRLMQNFSFKLCKETQVPLKLGKQGLLQPEKPIVLKVVSRDGIIRGA
What is the function of this protein?
Exhibits progesterone 6 beta-hydroxylase activity.
What are the official names of this protein?
Cytochrome P450 3A6, CYPIIIA6, Cytochrome P450-3C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: CAHM5_DANRE
Sequence: MDSFKTVLKFFTDQKTTIGYSVMAILTIGSERIFSMVSFQCPCTKGQNFPYGICFLLGPAVVLLVVGFFVSTRFWRLYTGCCLNPLKLCPRGNFVGCLKGLIKVLYGACVAPVMWLTVALLNGTFYECAVSGLDEVAVIQIFCADKGSVCQDELHRVPCGKSTLPPEQNTELLYMLRAQSQILGWSVIITAVVIALIGTCYKNCVSQVSYLQLTFWKIYMEKEREKFDAFANDYATKLADRNLKSFFDNKLPEEFPFPNHKAWEEISAIYNFRKSEQHYSTLQRYVERSDRDYSPDEHPMVEMDHGIEMV
What is the function of this protein?
Pore-forming subunit of a voltage-gated ion channel.
What are the official names of this protein?
Calcium homeostasis modulator protein 5, Protein FAM26E.
What is the protein family that this protein belongs to?
Belongs to the CALHM family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MSCL_GEOKA
Sequence: MWNEFKKFAIRGNVIDLAVGVIIGGAFGKIVSSLVNDIIMPLVGLILGGINFSDLSWKVGKAEVKYGAFIQTVVDFLIIAFSIFLFVKLINTLYERVKKQEEVKETAPTLTKEEELLTEIRDLLKQQRETT
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TI214_CUSGR
Sequence: MNFQYLVKIVAGSYYNISSSILSKIINSVIMAGLYYGFLTALALKTSYILLIHAMVRENPNHKAAAITGLILGQLGQLLSIYYAPLYIAFGRPYTLTVLTLIYFLVNLFGNNLDKNASSFGAYGNTIRNLEILCIFLNNLILQLLNTCIFPSSTLARVVNVYLFRCNNKMVFLISSFSAWLIGQILVLMCCQLVLGRGQNKNSIRSLIQKYLVRNSMFFLVVNCLFGSSLFILTIQSLGRIPLPIPTQKLSEISRIEKREEERLKKSGVAKEGKSTEDEEDLSHEKDSLKKEPYSKLENEDEEIEKDIEQAIGTLLFDYKRWTRPFRYIKNNQFEQAVRNEMSQYFFATQQSDGKSRICFTYPVNLSMFWKGISFLSRDKNYSNKLNRHWVERNKKKLKSLKRDLVNRIKNLDKTLKIEFGTTRTRLCTCIHDDETKQEYVPEEYDPLLAGGYRGRIKKEQAILQKQENETLTHPLDTLIDVLENNTNAQLFKTNPIDNQKINFEEELRKKVPRWSYKLITELEQISYYRNPPDDHDIRTRKAKSLVVFDPSKHPNMETMEDNGNIQNNSSDKTINPQNNLTNLKPRTSENDPDDNTTEKEPKDDKSYSIRYSHQSDFRHGLIKDSMRSLRRKIVIKDLFKGNVHSPLFFERRKKKNLFSFSGLVKLKKLFIPGSAQKEFGDLKDSNKKLTIKDKKQQETKERIEIAEAWDSFELTQVLRGVLLVTQSSLRRDILLPSLIIIKNLGRILLFQSSELSDDFKELAKETHVPCTYNGVPLGEKEFPRNWLTEGIQIKILSPFCLKPWNEEKKPLPASENFCFLTIWGQETDQIFGRPRRRPSFFKPFLTKLDTTLKKINLFQFFKEKRTPESNMVKEQKVDDLSDNILNEFQFSKREKLEAITNRTSIIKTKLETIAEEKKKVTRDLDRSLSKKSLKRIRFKLVSNLFPFQSFLKLFIQEIYNLFLRNILLISGLLKKILNREKEKLINQSCSKNEKMKKVHKKFNFSLNRKSKPSTNFSNLSQAYVFYKISQQIASFSVCKLRSILNQQVKAIFVKPEIKEFFARHGLIQTQEMDKKSIQLRTPQWKHWLRVNSQHHLSQILWFSFGAKKENWRKKINRCNKQSLQKRNSSGNSNLDDSKNRNTDNLILNKNQKDNFEKCYRYDVLSSKFIKFEKKKISFIHRSPLSLTRQHQISYHKNMSQNFLFALPKNMSVKNLMGKSQRMHIPYIEKDFDRKYLSFENIEFSLKKKINIESWIPLTSRGNKTKTYNYEFLDELELMEFIDQIYKKEKELLFPCIERNNKIRNAKSKYSFIDWMGLNEELLKHPVTNLELWFFPEFVSLLNIYKLKPWVLQSQLLFSKLTFNKLLSKQQNQTTTKMNTETKNKQKSKVENEKNKKTENQQNAETKNKQKSKTENEGNKETENQQNDESEDDPQLAYIRSFMKKHLLFQLRGESIFKKSGFKNIQILCLLLRLMNQNEMLFSSIQRQKLNLHIMPEIGIKELTLEVLEEIGVPEFLKEKRVNFEPFPLYINKNGKFLMYQLLNMSLVHNIKYPTNNESRNQGVITTQKNNNMASHIPENILSSRRRRELRILMCLNHNKKKCESTEATNKSFIYKKKCAKIWEEQKSTIEFFIWPNSRFEDLTCMNRYWFYTNNGSRFSMLRIFMYLPLKNY
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: PU92_BRACO
Sequence: MKQFIVLTVVLLAIQELQGGSVVTVDDKCTCKDTLNTLTKGQLIDRLVLCNQRNDNLEKIIDGLKKENNILRKENDGLRAENCQLSEALKREKEARQKAEKALKECQKNTENLKETIEQLKKELAEAQKALEKCKKELADCKKENAKLLNKIEELNCTITQLQEKLERCRGRERDLQCQLDECKKKLNICNNELIACRKQQEELRCKIERLNTEIEKLRKQNAACEKDLNTLRCETSEFLAIATQRQSQLTSIIQRAEGESSAIKASYIGFRNSHDLTCAPCAGPA
What are the official names of this protein?
Puff II/9-2 protein.
Protein: UBA1Y_MOUSE
Sequence: MSSSVLSKKRKVSGPDSSLDSSWSPTYSVMFGVPPGPTNEMSKNKEMDIDESLYSRQLYVLGHEAMKHLQASSVLISGLQGLGVEIAKNIILGGVKAVTLHDQGIAQWADLSSQFCLREEDIGKNRAEISQPRLAELNSYVPVFAYTGPLIEEFLSGFQVVVLTNTPLEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDSNGEQPLSAMVSMITKENPGIVTCLEDSRHGFESGDFISFTEVQGMSELNGIGPIEIKVLGPYTFSICDTSSFSEYIRGGIVSQVKVPRKINFKPLLASLAEPEFVVTDFAKCCHPAQLHIGFQALHQFCTQHSRPPRPHNEEDAEELVTLAQSVNAQALPAVQQDCLDIDLIRKLAYVAAGDLAPMNAFFGGLAAQEVMKACSGKFMPIRQWLYFDALECLPEHRVAFMEDKCLPHQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEDGEITVTDMDTIEKSNLNRQFLFRPWDITKLKSETAAAAVRDINPHIRIFSHQNRVGPETEHVYDDDFFQKLDGVANALDNVDARLYVDRRCVYYRKPLLESGTLGTKGNVQVVVPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTVQWARDEFEGLFKQSAENVNQYLTDPKFMERTLQLAGTQPLEVLEAIHCSLVLQRPQTWADCVTWAYQHWHTQYSHNIQQLLHNFPPAQLTSSGALFWSGPKRCPHPLTFDINNPLHLDYVMAAANLFAQTYGLGGSQDCAVVAKLLQSLPVPKFAPKSGIRIHVSEQELQSTSATTIDDSHLEELKTALPTPDKLLGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYGISPADRHKSKLIAGKIIPAIATTTSAIVGLVCLELYKVVQGHQQLESYKNSFINLALPLFSFSAPLAPECHQYYDQEWTLWDRFDVQGLQPSGEEMTLKQFLDYFKTEHKLEVIMLSQGVSMLYSVFMPASKLKERLDQPMTEIVSCVSKQKLGHHVKSLVFELCCNSDSGDDIEVPYVRYIIR
What is the function of this protein?
Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (By similarity).  The Y chromosome form could be involved in the survival and proliferation of differentiating spermatogonia.
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 1 Y, Ubiquitin-activating enzyme E1, Ubiquitin-activating enzyme E1 Y.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
Protein: IF1_LACLS
Sequence: MAKDDVIEVDGKVVDTMPNAMFTVELENGHQVLATISGKIRKNYIRILPGDKVQVELSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRYGS_MACFL
Sequence: MSKSVAKITFYDDKNFQGHHYECDSDCPDFHTYLSCCNSIRVTGGAWVVYERPNFSGNMYILTQGDYPDYHHWRGLNDRLSSCKVIHLSSGGQYKLQIFERGDFSGQMYETTEDCPSVMEQFHIREIQSCKVLDGVWVFYEQPNYYGRQYFLDKKEYRKPVDWGSPCSAVQSFRRIME
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin S, Beta-crystallin S, Gamma-S-crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: PIKM2_ORYSJ
Sequence: MELVVGASEATMKSLLGKLGNLLAQEYALISGIRGDIQYINDELASMQAFLRDLSNVPEGHSHGHRMKDWMKQIRDIAYDVEDCIDDFAHRLPQDSISDAKWSFLLTKIYELWTWWPRRVIASNIAQLKVRAQQIADRRSRYGVNNPEHLDSSSSARTRAVNYEIAEYQVTSPQIIGIKEPVGMKTVMEELEVWLTNPQAENGQAVLSIVGFGGVGKTTIATALYRKVSEKFQCRASVAVSQNYDQGKVLNSILSQVSNQEQGSSTTISEKKNLTSGAKSMLKTALSLLRGNCICQPENDGNPDNTPIRLQETTDDDQNPRKLEQLLAEKSYILLIDDIWSAETWESIRSILPKNNKGGRIIVTTRFQAVGSTCSPLETDRLHTVDFLTDDESQNLFNTSICESKIRKDSNKVDEQVPEEIWKICGGLPLAIVSMAGLVACNPRKACCDWSKLCKSLFPEQETPLTLDGVTRILDCCYNDLPADLKTCLLYLSIFPKGWKISRKRLSRRWIAEGFANEKQGLTQERVAEAYFNQLTRRNLVRPMEHGSNGKVKTFQVHDMVLEYIMSKSIEENFITVVGGHWQMTAPSNKVRRLSMQSSGSNRGSSTKGLNLAQVRSLTVFGNLNHVPFHSFNYGIIQVLDLEDWKGLKERHMTEICQMLLLKYLSIRRTEISKIPSKIQKLEYLETLDIRETYVRDLPKSIVQLKRIISILGGNKNTRKGLRLPQEKSKKPIKNPSPQGKTKEPAKKGFLSQEKGKGAMKALRVLSGIEIVEESSEVAAGLHQLTGLRKLAIYKLNITKGGDTFKQLQSSIEYLGSCGLQTLAINDENSEFINSLGDMPAPPRYLVALELSGKLEKLPKWITSITTLNKLTISVTVLRTETLEILHILPSLFSLTFAFSLSAAKQDQDIIKDILENNKLDSDGEIVIPAEGFKSLKLLRFFAPLVPKLSFLDKNAMPALEIIEMRFKDFEGLFGIEILENLREVHLKVSDGAEAITKFLVNDLKVNTEKPKVFVDGIVTA
What is the function of this protein?
Disease resistance (R) protein.  Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein.  That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.  Contribution of Pikm-1 is required to recognize the effector avirulence protein AVR-Pik.
What are the official names of this protein?
Disease resistance protein Pikm2-TS.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: OAZ2_MOUSE
Sequence: MINTQDSSILPLSKCPQLQCCRHIVPGPLWCSDAPHPLSKIPGGRGGGRDPSLSALIYKDEKLTVTQDLPVNDGKPHIVHFQYEVTEVKVSSWDAVLSSQSLFVEIPDGLLADGSKEGLLALLEFAEEKMKVNYVFICFRKGREDRAPLLKTFSFLGFEIVRPGHPCVPSRPDVMFMVYPLDQNLSDED
What is the function of this protein?
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels.  Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers.  Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity (PubMed:16916800, PubMed:18508777, PubMed:24967154).  Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol (PubMed:19449338).
What are the official names of this protein?
Ornithine decarboxylase antizyme 2, AZ2, ODC-Az 2, Seizure-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the ODC antizyme family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VPS4_BOMMO
Sequence: MTSSNTLQKAIDLVTKATEEDKNKNYEEALRLYEHGVEYFLHAVKYEAQGERAKESIRAKCLQYLDRAEKLKEYLKKDQKKKPVKDGESKSDDKKSDSDSDSDDPEKKKLQGKLEGAIVVEKPHVKWSDVAGLEAAKEALKEAVILPIKFPHLFTGKRIPWKGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKNLFDLARQHKPSIIFIDEIDSLCSSRSDNESESARRIKTEFLVQMQGVGNDMDGILVLGATNIPWVLDSAIRRRFEKRIYIALPEEHARLDMFKLHLGNTRHQLSEQDMKLLAAKSEGYSGADISIVVRDALMQPVRKVQSATHFKKISGPSPTDPNVIVNDLLTPCSPGDPGAIEMTWIDVPSDKLGEPPVTMSDMLRSLAVSKPTVNDDDMVKLRKFMEDFGQEG
What is the function of this protein?
Involved in late steps of the endosomal multivesicular bodies (MVB) pathway.  Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 4, BmVps4, Vacuolar protein sorting 4.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Prevacuolar compartment membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Midbody. Cytoplasm. Note=Membrane-associated in the prevacuolar endosomal compartment. Localizes to the midbody of dividing cells.
Protein: EFP_SALPK
Sequence: MATYYSNDFRSGLKIMLDGEPYAVESSEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT24_MOUSE
Sequence: MAWSASVRGLGQRVLACSRELPGAWRTLHTSAVCAKNRAARVRVAKGNKPVSYEEAHAPHYIAHRKGWLSLHTGNLDGEDHAAERTLEDVFLRKFMMGTFPGCLADQIVLKRRANQVDICALVLRQLPAHKFYFLVGYSETLLSHFYKCPVRLHLQTVPSKVVYKYI
What are the official names of this protein?
28S ribosomal protein S24, mitochondrial, MRP-S24, S24mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TETR1_ECOLX
Sequence: MTKLQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHFRNKRALLDALAEAMLAENHTHSVPRADDDWRSFLIGNARSFRQALLAYRDGARIHAGTRPGAPQMETADAQLRFLCEAGFSAGDAVNALMTISYFTVGAVLEEQAGDSDAGERGGTVEQAPLSPLLRAAIDAFDEAGPDAAFEQGLAVIVDGLAKRRLVVRNVEGPRKGDD
What is the function of this protein?
TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA.  Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
What are the official names of this protein?
Tetracycline repressor protein class A from transposon 1721.
Protein: RNPA_OENOB
Sequence: MGTKKPFRIKKTSDFQRVFAKHKSFANRYFVVYSDTQPKEVDVSHWRIGLSVSKKIGKAHERVWVKRRISESFNNISLFIPNNLDIVIVARPLVKGQKQKIIQDQLMHVLDLAGILNGKEKN
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: ISCS_SHEON
Sequence: MKLPIYLDYAATTPVDPRVAEKMFQYMTMDGIFGNPASRSHRYGWQAEEAVDVARNQVADLINADHREIVFTSGATESNNLAIKGVAHFYKKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLEPESNGIIPMARLEAAMRDDTILVSIMHVNNEIGVIHDIDAIGELCRSKGIIFHMDAAQSAGKLPIDVQATKVDLISISGHKMYGPKGIGALYVRRKPRIRLEAQMHGGGHERGMRSGTLPTHQIVGLGEASAIAKAEMATDNVRIAKLRDKLWNGIKHIEETYVNGDMNQRTSGSLNVSFNYVEGESLMMALKDLAVSSGSACTSASLEPSYVLRALGLNDEMAHSSIRFSIGRFTTEEEIDHAIEVITQSIDKLREMSPLWEMFKDGIDLNQVQWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_SALPC
Sequence: MTKSELIERLATQQSHIPAKAVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.