PharMolix/UniProtQA huggingface dataset:
Protein: RL23_SULNB
Sequence: MADITDIKSIMYTEKSLALQEEGVIVVQTTPRMTKNGLKEVFKEFFGITPLRVNSMRVNGKVKRFKGIEGKRPDLKKFYVKLPEDAKIESLAV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RSMG_CHLPM
Sequence: MKQQNNDGDQLQSFCTNEGIQITDEQHQLLVRYAQMLESWNTKVNLISRKEDAPVLIRHVFHSLLPSLVHNFRDGETVLDLGTGGGLPGIPLAIMYPQVQFLLVDSTGKKITACSAMIEELGLTNARAMHTRVEELKGLAFNTILSRQVAPLKELSRYAAPLLKKNGELICLKGGDLQKEIDEALREGKKRKGFPGSVTLKPIGEVSPLFNEKQIVIARWR
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_STAHJ
Sequence: MARFRGSNWKKSRRLGISLSGTGKELEKRPYAPGQHGPNQRKKLSEYGLQLREKQKLRYLYGMTERQFRNTFDIAGKQHGVHGENFMILLASRLDAVVYSLGLARTRRQARQLVGHGHVEVDGRRVDIPSYSLKPGQVITVREKSQNLDIIKESVEINNFVPEYLDFDADSLKGTFVRFPERSELPAEINEQLIVEYYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: EFTU_CARRP
Sequence: MAKKKFNREKIHLNVGTIGHVDHGKTTLTAALTKVSSDLYGSECRPFDSIDNAPEERERGITISTSHVEYESETKHYAHVDCPGHADYIKNMITGAAQMDGAILVCSAVDGPMPQTREHILLARQVGVPTIIVYLNKADCVKDKELLELVEMEIRELLTEYDFDGNNTKIIIGSALLALENKDDNQLGTSSIIKLLEILDKNIPVPNRIIDKPFLMPIEDVFSISGRGTVVTGKIERGIIKTGEEIEIVGFKETIKTIVIGIEMFKKTLDEGFAGENVGILLRSIKREEVERGQVLIKSGTIKPHTNFICEVYILSKEEGGRHTPFFKGYKPQFYFRTTDITGICDLPKNIEMVMPGDNVKLIVKLLSSIAIEKGLRFAIREGGKTVGAGIITEVLND
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBG_YARLI
Sequence: MTEDFTPNAGYIEVKPPARPRQNIAKDNQQMRLALLRVKRYETAVQRLQEEQDRERQTARQAGRDLIKYTTSVKDHAVPELWGYLPPEKNPYALYEEENKTTGCCVIS
What are the official names of this protein?
Guanine nucleotide-binding protein subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: TT9_ARATH
Sequence: MWLSFLRPRDRFSLAELRYLTDQLRKIQIVNEANKDLVIEALRSIAEILTYGDQHDPLFFEFFMEKQVMGEFVRILRVSKTVTVSVQLLQTMSIMIQNLKSEQAIYYLFSNEYVNYLITYTFDFQHEELLSYYISFLRAVSGKLNKHTISLLLKTENDVVVSFPLYVEGIQFAFHEENMIRTAVRALTLNVYHVGDESVNDYVVSPPHTEYFSKLISFFQKQCMDLSAMVLNTLKSPSPDSGGKLFSAVDGIEDTLYYFSDVISAGIPDIGRLITDHILQHLTLPLLLPSLCSEAVNDISVDPVTSLYLLSCILRIVKIKDLANMTAATLFCPVKAFISSSLVKPNSSLAPEGLTYVNGHPDKGVTEEANQQCSSTAAGMSDDGNSHLCSEDTPKSIFNNSHMTFRETLLQYISEGDDVQAQGSLFVLATLLQTKELEESMLDAFGILPQRKQHKKLLLQSLVGEDTGEEQLFSPRNGSMRDGLSSELDWYLRRLEEQFGVCCSLPGAARCPRVHRHQVVDTLVTLLCRENISAETLWDGGWLLRQLLPYSEAEFNRKHLKMLNVSYEKCKNSLTREIKGIWPDLLIRVLLDEWRKCKRVIEAPSPQKEPKSVLLQLDRSSSNDNSVSESSFTAGERMCEVVKVFVLLHQLQIFSLGRSLPEQPPIYPPADRSETSRATRAGLDVSVPKPGTELKLVDAVPCRIAFERGKERDFSFLALSSGESGWIVLADPDNGIVRVTAPLAGCKPRIDEKHPRWLHLRIRPSTLPLLDPTKRGVYEKLKSKGLVDGRWILAFRDDESCHSAYSMVAGEIDLQCSEVERRLRPLFDLERNQLEDQ
What is the function of this protein?
Involved in membrane trafficking and vacuole development through membrane fusion at the vacuole.  Required for membrane trafficking machinery and accumulation of flavonoids in the seed coat.
What are the official names of this protein?
Protein TRANSPARENT TESTA 9, Protein GREEN FLUORESCENT SEED 9.
What is the protein family that this protein belongs to?
Belongs to the CLEC16A/gop-1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: YCCT_ECOLU
Sequence: MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLLRGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLENEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASLPQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQPSS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: SRP54_THEAC
Sequence: MVLESFSASLRETIRKITGSSYIDKETVKEISKDLQRILLKADVNVKTVLQVTKEMERRALEEKPPAGMAHQDYMVRIIYEELLKILGEPSNVKLKPQTIMLVGLYGNGKTTTAGKLARFFAKKGLNSGLIAADVHRYAAYDQLKQIASEVNAKFYGDQSEKDPVRLIKHGLEQLKDVAVKIIDTSGRDSMDAELFDEIRRIKEAVAPDEVLMIIDATMGQQAGPEAKAFNDAIGVTGIIITKMDGTAKGGGALSAVAEIHVPIYFIGTGEHMDDLEVFDPKKFLSRLLGLGDLESLFETVQEADITEEEAQESFEKLMTGKFNLKDMYDVWEKFSKPGLMKKLVDALPLARIPGSQKIDDSKIQSAEDKLRMYRIIMDSMTFEELENPEIINAKRITRIARGAGVREEDVRMLLKEFKAMKNNMKMMKGNRGLKKMLQANFRSGNFGLEDLGIKE
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: MNMA_PARUW
Sequence: MKNQKTVVVGMSGGVDSSVSALLMKEQGYNVIGLFMKNWEEKDENGVCSSAQDYDDVRRVCDHINIPYYAVNFVENYRKQVFTQFIADFQKGWTPNPDILCNREIKFKVFLEKALELGADFLATGHYCQNLILDKGSPSLVKGIDHNKDQTYFLYTLNQQILQQVLFPVGGLEKSQVRDIARKHQLVTAEKKDSTGICFIGERDFRSFLSQYVAIQPGAFQTLQGKNVGKHMGTAYYTLGQRKGLGIGGAGEAWFVVGKDHERGIVFVEQGANHPALYCDELIATDLSWVAEAPLLPYTCQSKVRYRQNDQFCTIHRIENGKAFVTFDRPQRAVTPGQSIVFYVGNICLGGGVIQQPGPTYYDQKKSLPHQSPRND
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_MYCCT
Sequence: MKNNILEELKWRGLIKQVTNEQKILDAQNSNDAVYCGFDPTADSLHVGHLMMIITLKRFALQGFKPIALIGGATGMIGDPSFKASERVLQTKQQVDHNINKISTQLKEIIPTVSFVNNRDWLEDISLIDFLRDIGKHFNLSYLLAKESIATRIQTGLSVTEFCYTMLQAFDFYYLYKNNDCSVQIGGSDQWGNITSGIDFISDTINKNNKASGVTINLLTKSDGQKFGKTESGAVWLDKTKTSEYEFYQFWFNQTDEDSINLLKCLTFLTKDQIEQLIKQHNQQPAKHFLQKALASEMTKFVHQQQGLDKALKLTEAFFSGDLFSLTDDLFKMALNSLPNTQINKDTKVIDALVELKVASSKREAREFLKNKAILINNQVIEDENLVISSFDLIQNKYLLVKKGKKKYFVILVK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_BURTA
Sequence: MIETDKLAAERIIAATPASSHEEAFERALRPRQLDEYVGQEKVRDQLEIFIEAAKRRAEALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYDAEQLSRIVRRSAALLNAQIDPAGALEIAKRSRGTPRIANRLLRRVRDYAEVKADGNITAAVADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGVDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRVATLLTYRHFGLATPDAASPVRNLWDTPDAER
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: DNLI4_EMENI
Sequence: METDQDMHDQAMAGEETDLDEKYPNRPQNKAPTLPFHDLYETLFRPLREIKKKPVGPAGNRRKAGPHGLSAANLNPIERRRDIIERFISRWRKEVGDDIYPAFRLILPDKDRDRAMYGMKEKIIGKMLVNIMKIDKNSEDGFNLLNWKLPGQSATSSMAGDFAGRCYDVVSKRPMRTEFGNMLIEEVNEKLDQLSSASKEEEQLPILAEFYRRMNPEELAWLIRIILRQMKLGATERTFFDVWHPDAENLYSISSSLRRVCWELHDPNIRLDAEDRGVSLMQCFQPQLAQFQMQSLDRMIARMRPTEDDPVFWIEEKLDGERMQLHMVSDASAPGGRRFRFWSRKAKDYTYLYGNGIYDEAGSLTRHLKDAFADGVDNLILDGEMITWNTEQDAPEPFGTLKTAALSEQRNPFRQGIHPLFRVFDILYLNGRDLTRYTLRDRRNALQKVIKPVHRRFEVHSYEEATTKAEVEASLRKAVAEASEGLVLKNPRSPYRLNERHDDWMKVKPEYMTEFGESLDLVVIGGYYGSGHRGGKLSSFLCGLRVDEGQSSQGSNPTKCYSFCKVGGGFTAADYANIRHHTDGKWVEWNPKKPPTTYIELAGGDSQYERPDMWIKPEDSVVICVKAASVSVSDQFRIGLTLRFPRFKRLRMDKDWKSALSVQEFLDLKSHAEQEHREKEFNVENFRKKRVKKTTKKPLAIAGYDENAEVQYAGPSGHIFDGLNFFILTDSNAPVKKSKAELENLVKANGGRIFQTNDAVPDTICIADRRTVKAASLQKKGDIDIIRPSWILDCIKQSEIDAGLPDLLLPLEPGHMFFMTKDKEEIVAGSLDQFNDSYARDITVEELRNLLDQMAKDGKTDSFCSPEAIQKVTEHIQEKVDSGWTMPCGWLFKGLVLCFPENENDSASEGPEPKQSQRIHLAQNTAKFAGASVTTSLKDTSITHVVVDPDFTSSELPKLRRTLSTRRKLPHIVKVNWIEDSWKENTLLDEEQHMPVYMRRYPNIQLMKV
What is the function of this protein?
Involved in ds DNA break repair.  Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining.
What are the official names of this protein?
DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADIA_ECOLI
Sequence: MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGFAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMDRDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAPGHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVFGADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQDLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALSQASYIHVREGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQTGKTYDFADAPTKLLTTVQDCWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVTAWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKRHYDANTPLAQVMPELVEQYPDTYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPVAEVTPREAYNAIVDNNVELVSIENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSYLRSLQSWDHHFPGFEHETEGTEIIDGIYHVMCVKA
What is the function of this protein?
Component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach (Probable).  ADC can be found in two forms: biodegradative (this enzyme) and biosynthetic (speA).  The biodegradative form plays a role in regulating pH by consuming proteins.  Converts arginine imported by AdiC to agmatine which is then exported by AdiC (Probable).
What are the official names of this protein?
Biodegradative arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_COXB1
Sequence: MTTITPIMVKELRERTGAAVMACKKALQETNGDMEAAIDLLRKAGDAKAAKRAGKTAAEGVIVIAISKDQKKGFMAEVNSETDFVARDTNFMAFASKVAERGLAEGVSDVAATLALPIEPNSSSTIEDERKALVNRIGENIQIRRVASLSSDGVVGHYSHGGRIGVLLALDVPNPELVKGLAMHVAAFNPQAVSANQVSTEFVEKEKEIFLARAQETGKPANIIEKMVKGQVEKLLKEVSLEGQSFVKDPEKLVGDLLKAEKAKVLAFLRFEVGEGVEKESQNFADEVMAQVQGNR
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_BURP6
Sequence: MNAVTESAATTEMPAPFVFTDAAADKVKQLIDEEGNPDLKLRVFVQGGGCSGFQYGFTFDEEVNEDDTVLNKNGVVLLVDAMSYQYLVGAEIDYKDDLNGAQFVIKNPNATTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: CHMP3_DICDI
Sequence: MFSFLKKPTPEELVKKWKRELRREDRGLDTQLRAIDMQEKKTVRMIKERVKAGDQKSAKTLAKEIVNSRKAKERIYTAKAQMNSVSMQLQSNLAMTKVQGNLAKSTEIMKMMNDLIKLPELNKVMMAMGSEMTKAGIMEEMISDVFDMQGEDLEEEAEMEVNKIMDEILVSGPQVSSAPLETHQQEEVVQEKQEDSELLDRLKALKS
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 3, Vacuolar protein-sorting-associated protein 24.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein.
Protein: PHCA2_SYNP6
Sequence: MSKTPLTEAVAAADSQGRFLSSAELQVAFGRFRQAASGLAAAKALANNADSLVNGAANAVYSKFPYTTSTPGNNFASTPEGKAKCARDIGYYLRIVTYALVAGGTGPIDEYLLAGLDEINKTFDLAPSWYVEALKYIKANHGLSGDSRDEANSYIDYLINALS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
C-phycocyanin-2 alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of the phycobilisome rod.
Protein: NFUA_SHELP
Sequence: MITISDAAQAHFVKLLADQPEGTHIRVFVISPGTPSAECGVSYCPPDAVEADDIELEFNGFHAMVDEKSAPFLEDASIDFVTDQLGSQLTLKAPNAKMRKVDADAPLKERIEYVIQSEINPQLASHGGNIMLVDIDEAGIAILQFGGGCNGCSMVDVTLKDGIEKQLLDMFPGELTGVRDVTEHQHGEHSYQ
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: HBB_COLLI
Sequence: VHWSAEEKQLITSIWGKVNVADCGAEALARLLIVYPWTQRFFSSFGNLSSATAISGNPNVKAHGKKVLTSFGDAVKNLDNIKGTFAQLSELHCDKLHVDPENFRLLGDILVIILAAHFGKDFTPECQAAWQKLVRVVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: HIS6_METMP
Sequence: MLTKRIIPCLDIKEGRVVKGTNFVELRDAGDPVELSKIYNEQGADELVFLDITASFEKRDIIIDVVKRTAEQVFIPLTVGGGIKTVDDFRKILRAGADKISINTSAVKTPDLIKEASEIFGTQCVVVAMDVKRKYITDSQDENLKNKNIFETKLGSCWFEVYIYGGREGTGIDAIEWAKKVEYLGAGEILLTSMDADGTKDGYDLVLTKAISENTKLPIIASGGCGNANHVVDAFTEGKADAALMASILHYRECTVNDLKKEVEKNNIPVRF
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USP13_LOTGI
Sequence: MMWNYFVTCIVLYANIISIHTFGLTGGNNLNQALGLTGGNPLDSTLGLSAGNAFPSGMGAMQIPAYLRMAPSVETICSTQSPLLNPRERNGLLSDLVGKEISRRSRFLAANPSLAGTGKWACAANYYSNVMRYRPNELGNVFGDLIDSTGCDGFTCDMVRGVRKTSPMSNFLNAMMISQMMQQPNAAQVPTTSQQQPTSNTGGQQPPTNASNPPTNPQPTPTPAQPTPSGTQVQQTPAANNGLDLTSMFNNPAFQEQLMRLVST
What are the official names of this protein?
Uncharacterized shell protein 13, LUSP-13.
Protein: FBPC_AGRFC
Sequence: MITVKPGSVVFENVRKTFGAFTAIPDLSLTIEPGTLVTLLGPSGCGKTTTLRMLAGLEHPNSGRILIGGKDVTMLPANERDVSMVFQSYALFPHMSALDNVAYGLQSSGLKKAEAREKAEEGLKLVGLAGMGHRLPAELSGGQQQRVAVARALVLEPQVLLLDEPLSNLDARLRRRVRTDIRELQQRIGFTAVYVTHDQDEALAVSDRIIVMKEGEIAQSGAPRELYEAPASSFIADFMGEANVVPCEVVSQTGDESLVRVGTMEHRVRSRGPRSGSAKLAVRPGAITIGAAGGSGMPGRVLHTAYLGGHIEYEVETEVGTLFIIDHEMNHTQRETSDVTLNFKNRGIALIDA
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CFM1_MARBU
Sequence: MKFSAPVLAIFLASASAQSTAELAAQIPSCAQTCLATAITGAGCTAGDYACQCGTSQNTITASATPCVISACTSEEALNTQRTTSQICALVAAGSASSPSASSSASASASSSASSTSGAASASASASSSASSASAAASALTLAHPIPNPSHPPSPTIQTNLRKKVRNSNRLTPASLSSVSSALVSSASSVRASASSAVSAATTAANPAATTAAGVKEEASFFIPAAVALFAVFAV
What is the function of this protein?
Appears to function during host infection, and may play a role in suppressing the host immune response.
What are the official names of this protein?
Effector CFEM1, MbCFEM1.
What is the protein family that this protein belongs to?
Belongs to the RBT5 family.
Protein: FABZ_STRT1
Sequence: MTIDINAIREALPHRYPMLLVDRVLEVSEDEITAIKNVTINEPFFNGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQLVMTAKFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGS
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_AERPE
Sequence: MILSDRDIRALLAIGDLVVEPLSGDTVRENGLDLRLGRGFCRFKRSDRVLDPRAPGSPGEFYECGEGDEIIVGPGEHMLLHTQEYIRLPGYVAGLVNLRSTWARTGIYIPATVVDAGFEGQLTIEVVGSGFPVKLYPGDRFLHLVLVKLQSPAMNPYRGRYQGQRGVRLPKLFAKNTG
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RL22_BUCCC
Sequence: MNVLAKYNQVRSSAQKIRLIANIIRGKKALLALQILSSVKKKAALLVKKLLKSALSNAEHNYGYNKEVLIISKIFVNSGSSMKRMMPRAKGRADRILKRTSHITVILSDIKKNPEGYNGSKSTP
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL14_BACAC
Sequence: MIQQESRLKVADNSGARELLTIKVLGGSGRKYANIGDIIVATVKQATPGGVVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIKDDKSPRGTRIFGPVARELRDSNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GLUC_PIAME
Sequence: HSEGTFSNDYSKYLETQRAQDFVQWLMNSXXXXXXXXHADGTYTSDVSAYLQDQAAKDFITWLKSGQPKQE
What is the function of this protein?
Plays a key role in glucose metabolism and homeostasis.  Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.
What are the official names of this protein?
Pro-glucagon.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: YBHF_ECOLI
Sequence: MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGAGKTTLMRMLAGLLKPDSGSATVIGFDPIKNDGALHAVLGYMPQKFGLYEDLTVMENLNLYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVLLLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQGEPKALTQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKEATPDDIRHADGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKELTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMDLKESSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGLKSIASHATDELPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVEKGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTMEQAFIQLIHDWDKEHSNE
What is the function of this protein?
Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Probable multidrug ABC transporter ATP-binding protein YbhF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: NU4M_BOTSC
Sequence: PIAGSMVLAAILLKLGGYGMIRMMQILPTTKTDMFMPFIVLALWGAILANLTCLQQTDLKSLIAYSSISHMGLVVAAIIIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRILIMTRGFHNILPMTTTWWLLANLMNIAIPPSMNFTGEFLIMSALFNWAPTTIILLGLSMLITASYSLHMFLSTQMGPTQLNNQTEPTHSREHLLMTLHLIPLMMISMKPELIT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.