PharMolix/UniProtQA huggingface dataset:
Protein: ADAM7_MACFA
Sequence: MLPGCIFLMILLILQVKEKVILGVEGQQLVYPKKLPLMQKRDIGHTHDDDIEETYEEELMYEIKLNRKTLVLHLLRSREFLGSNYSETFYSMKGEAFTRHLQIMDHCFYQGSIVHEYDSAASISTCNGLRGFFRVNDQRYLIEPVKYSDEGEHLVFKYNPRVPYVANYSCTELNFTRKTVPGDTESEGDPKMKAIHNEKYIELFIVADDTVYRRNSHPHNKLRNRIWGMVNFVNMIYKTLNIHVTLVGIEIWTHEDKIELHSNIETTLLRFSSWQERILKTRKDFDHVVLLSGKWIYTHVQGISYPAGMCLPYYSTSIIKDLLPDTNIIANRMAHQLGHNLGMQHDEFPCTCPSGKCVMDSDGSIPALKFSKCSQNQYHQYLKDYKPTCMLNIPFPCNFDDFQFCGNKKLDEGEECDCGPPQECTNPCCDAHTCVLKPGFTCAEGECCESCQIKKAGSICRPAEDECDFPEMCTGHSPACPKDQFRVNGFPCKNSEGYCFMGKCPTRRDQCSELFDDEATESHDICYKMNTKGNKFGYCKNKENRFLPCEEKDVRCGKIYCTGGELSYLLGEDKTYHLKDPQQNATVKCKTIFLYHDSTDIGLVASGTKCGDGMVCNNGECLNMEKVYNSTNCPSQCHENPMDDHGLQCHCEEGQAPVAWEETLNVTNVAILIVVLVLVIVGIGVLILLIRYQKCIKLKQVQSPPIETLGVENKGYFGDEQQMRTEPILPEIHFLNQRTPESLESLPTSFSSPHYITLKPASKDSRGIADPNQSAK
What is the function of this protein?
May play an important role in male reproduction including sperm maturation and gonadotrope function.  This is a non catalytic metalloprotease-like protein (By similarity).
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 7, ADAM 7, Epididymal apical protein I, EAP I.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MUTL_AKKM8
Sequence: MPSIHVMSPTLASQVAAGEVVERPASVVKELVENSLDAGAKFVRVEIRRGGVGMIKVTDDGSGMSRADAELCTKRHATSKLSSLEELFEITHLGFRGEALPSIASVSRFKLCTRQQQDLEGWEIRIDGGLEHEPRSSGVSPGTAIEVADLFYNTPARRKFLKSAETEASHVEHQIRLHALAYPQVRFAYKRDDQLVFDLPATADLRVRISALTDAATAAALIPIETTIGPGISITGFLLPLSEARRTRKGQYVFMNTRPVEDQLINRAIRDGYGGFPTGLHPALFLYMEVEPALVDVNVHPAKKEVRFRRSADVVNTIVEAIANTLQKHARQEIHAAAAPEPERTLPPAHSTTAPYGEIPARSTNPGSAFPAAARPAPASSAAQPPLSSSAKQSHGAVPPPTLRAIPLKQVPATQGKLDFHRQEDEETARNAHENAALERDASAGFSYLGTLRQQFALFETPEGLVLMHPKAARERIIFERLRARREAPMPSQQLLDPVVLDLDPRDFAVIRQFAPHFDQAGMAVTPFGQNTIRIESIPALLELENARAFLLELVDRLTQSEFSRNAKRVAYETFIGEFARKSAWRERISPHRAPAILKDLLACEVPYCTPGGKPTLVNYSVPEIKRKFGLQA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: IF3_STAEQ
Sequence: MSTIAKDQTQINEKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKYKFEQQKKEKEMKKKQKVINVKELRLSPTIEEHDFQTKLKNGRKFLSKGDKCKVSIRFRGRAITHKEIGQRVLEKFADECKDIATVEQKPKMEGRQMFIMLAPINEK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_ALKCK
Sequence: MAQVQYYGTGRRKHSVARVRLIPGEGKIVVNGRDLDEYFGLETLKLIVKQPLVETGVTGQYDVHVNVNGGGFTGQAGAIRHGIARALLQVDPDNRATLKAAGFLTRDARMKERKKYGLKAARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: IF1A_SCHPO
Sequence: MPKNKGKGGKNRRRGKNENENEKRELTYAEEGQMYAQVTKMLGNGRIEAACFDGVKRLGHIRGKLRKKVWINQGDIILLSLREFQDEKGDVILKYTADEARTLKNQGELPETAKINETDTFGAEGEDDLDFEFDVDAI
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 1A, eIF-1A, Eukaryotic translation initiation factor 4C, eIF-4C.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: RL11_SALPC
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NOP5A_ARATH
Sequence: MLILFETPGGFAIFKVLNEGKLSNVEDLGNEFSTAKLARKMVKLVAFDKFDNTAEALEAVAKLLEGTPSKGLRKFLKANCVGETLAVADSKLGNIIKEKLKIVCVHNNAVMELLRGIRSQLTELISGLGDQDLGPMSLGLSHSLARYKLKFSSDKVDTMIIQAIGLLDDLDKELNTYAMRVREWFGWHFPELAKIVQDNILYAKAVKLMGNRINAAKLDFSEILADEIEAELKEAAVISMGTEVSDLDLLHIRELCDQVLSLAEYRAQLYDYLKSRMNTIAPNLTALVGELVGARLISHGGSLLNLAKQPGSTVQILGAEKALFRALKTKHATPKYGLIFHASVVGQAAPKNKGKISRSLAAKSVLAIRCDALGDSQDNTMGVENRLKLEARLRTLEGKDLGRLSGSAKGKPKIEVYDKDKKKGSGGLITPAKTYNTAADSLLQTPTVDSENGVKEKKDKKKKKKADDEEEAKTEEPSKKKSNKKKTEAEPETAEEPAKKEKKKKRKHEEEETEMPAKKKEKSEKKKKKKTEV
What is the function of this protein?
Required for 60S ribosomal subunit biogenesis.
What are the official names of this protein?
Probable nucleolar protein 5-1, MAR-binding NOP56/58 homolog 1, NOP58-like protein F108, Nucleolar protein 58-1.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: AROC_MYCS2
Sequence: MLRWTTAGESHGRALVAMLEGMVAGVPITSEEIGAQLKRRRLGYGRGARMKFEQDQVTMLAGVRHGLTLGGPIAIEIGNTEWPKWESVMSPDPVDPADLDVARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTVARAFLREALGVEVLSHVISIGASKPYDGPAPQFSDLSAIDDSPVRAFDKASEELMIAEIEAAKRDGDTLGGVVEVVADGLPVGLGSFTSGENRLDSQLAAAVMGIQAIKGVEIGDGFETARRRGSVAHDEMYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDMTSGEEAVAIHQRSDVCAVPAAGVVVETMVALVLARAALEKFGGDSLAETRANIDSYLRAVAEREPAAQASS
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: FPG_GEOSL
Sequence: MPELPEVETTLRGIAPHVTGRRVTAVTARAAKLRLPIPPELGERLTGRVIERVERRAKYLLLRCGDGTAIIHLGMTGTLRVAPAGSPPGKYDHLDLVLDDGRTLRFRDPRKFGLVLWTGSDPLAHPLLAQLGPEPFPPLFNGSYLFSRSRKRNAAIKLLLMDNRIVVGVGNIYANEALFRARIHPERAAGSLSEEDCATLATAVGDVLRDAIAEGDTTLHEFIATEVPSGYFRINPAVYGQTGKPCTVCGTPIARIRLGNRSTWFCPVCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: LEU1_ECOBW
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITEYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: KGUA_KORVE
Sequence: MSGTIFIISAPSGSGKSSLVNELRHVVPGLEFSISYTTRAPRGSEQNGREYFFVTREKFDAMLAADEFLEHAEVFGECYGTAKHFVTEALARGNDLVLDIDVQGAAQLKVKLPDAVGIFILPPSRKELEARLKRRNLSDHVAPEVIERRLKGAGKEIENFSHYDYILVNDNFETAVEQLRAIVLAERIRRSSTQISEENRAILEAAECCIRKNAMQRVQSILDSFKDATDPQP
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED19_PICST
Sequence: MVNDNYNTAEGIDSYYLVNSKHKYSITSPSPLDNLLVLYGLEPIAKSLARTNADGSKGVKLRKSYKNHIQDLPGKHQIVGGQKPIPAGLLDPMVAQAPDIIKELDPELLSRGLRFEKTPINGIPGFNTADLAINDQHTLMRGDDMSENDEFGARRSKRKKKAQNGTDSKRQHI
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 19, Mediator complex subunit 19.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSLD2_ARATH
Sequence: MASNKHFDKSRSNLSNNSDIQEPGRPPAGHSVKFAQRTSSGRYINYSRDDLDSELGGQDFMSYTVHIPPTPDNQPMDPSISQKVEEQYVANSMFTGGFKSNTRAHLMHKVIETEPNHPQMAGSKGSSCAIPGCDAKVMSDERGQDLLPCECDFKICRDCFIDAVKTGGGICPGCKEPYKNTHLTDQVDENGQQRPMLPGGGGSKMERRLSMVKSTNKSALMRSQTGDFDHNRWLFETTGTYGYGNAFWTKDGDFGSGKDGDGDGDGMGMEAQDLMSRPWRPLTRKLKIPAGVISPYRLLIFIRIVVLALFLTWRVKHQNPDAVWLWGMSVVCELWFALSWLLDQLPKLCPINRATDLQVLKEKFETPTASNPTGKSDLPGFDVFVSTADPEKEPPLVTANTILSILAAEYPVEKLSCYVSDDGGALLTFEAMAEAASFANIWVPFCRKHAIEPRNPDSYFSLKRDPYKNKVKSDFVKDRRRVKREFDEFKVRVNSLPDSIRRRSDAYHAREEIKAMKMQRQNRDDEPMEPVKIPKATWMADGTHWPGTWLTSASDHAKGDHAGIIQVMLKPPSDEPLHGVSEGFLDLTDVDIRLPLLVYVSREKRPGYDHNKKAGAMNALVRASAIMSNGPFILNLDCDHYIYNSEALREGMCFMMDRGGDRLCYVQFPQRFEGIDPSDRYANHNTVFFDVNMRALDGLMGPVYVGTGCLFRRIALYGFNPPRSKDFSPSCWSCCFPRSKKKNIPEENRALRMSDYDDEEMNLSLVPKKFGNSTFLIDSIPVAEFQGRPLADHPAVKNGRPPGALTIPRELLDASTVAEAIAVISCWYEDKTEWGSRIGWIYGSVTEDVVTGYRMHNRGWKSVYCVTKRDAFRGTAPINLTDRLHQVLRWATGSVEIFFSRNNALLASSKMKILQRIAYLNVGIYPFTSIFLIVYCFLPALSLFSGQFIVQTLNVTFLVYLLIISITLCLLALLEIKWSGISLEEWWRNEQFWLIGGTSAHLAAVLQGLLKVVAGVEISFTLTSKSGGDDIDDEFADLYMVKWTSLMIPPITIIMVNLIAIAVGFSRTIYSVVPQWSKLIGGVFFSFWVLAHLYPFAKGLMGRRGRTPTIVYVWSGLVAITISLLWVAINPPAGNTEIGGNFSFP
What is the function of this protein?
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
What are the official names of this protein?
Cellulose synthase-like protein D2, AtCslD2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: DISA_CLOBA
Sequence: MRLEKGMKIKDTLKIMCPGTQLREGLENILRAKTGGLIVIGDNKEVMDTVDGGFTLNSDYSPSYVYELAKMDGAIVISEDLKKIVCANAQLIPDPSIITHETGTRHRTAHRIAKQTNNIVIAISQRRNIITVYKGDIKYVLRDSSVILARANQAIQTLEKYVSVLERVINNLNLLEFQDLTTLFDVVTAIQRTEMVMRIVEEINMYILELGNEGRLISMQLNELVKHIERDGILLIRDYCKEDFEYNEVYEQIQKLSAAELLDLDAIARLLGHTGDPLVDTLISAKGYRILGKVPRIPSTVIENLIKEFRELNSVIEADLDELDIVEGIGEARAKAIKDGLKRIREQILLNKKI
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation.  The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: RL16_STRMU
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKIMFEIADVPEEVAREALRLASHKLPVKTKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: LPXK_HALOH
Sequence: MVANMRKKLESYLINLIKSGPRSICDKIVLFILSILEKIYNLLILLRRLLYNLNLVKPGEVEARVISVGNITAGGTGKTPLVIYLAKKLAEENRVVVISRGYQSQSEGEEPSVVSDGRNILTDVSEAGDEVYMMATLLGGVPLITGSNRYKAARLASRRFNAEIIILDDGFQHWQLKRDVDIVMIDGLKPFGQGRLIPRGFLREPLSGLKRADFFVISRAHHISREKLQEIKDTLCQYNQNAVVYEATTSSVYLKELSVASLEMKSIIHKKRPLDELKGAKVIAVCGLGNPRSFYRDLEISGAEVIETLSFNDHHQYRPDDFDKIINLARQKAIDIVITTEKDAVKFSRDDIKKFIDHNINLYVLGIEISLKGTVDLAQVINKY
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: E1A_ADECC
Sequence: MKLTLEPAPRCLHEYVSQLLEDWQPECLSCEYSHGGSSPPSLHDLFDLELENSRSPSPLLCDWCAEADSESTISTETDVGFTLNTPPVSPLPSYSTSPASIPEDMLLCLEEMPTFDDGDEVRSATTSFEHWENNFDPNVGSFFGCLRCAYYQEQGENSICGLCYLKALAEEPVDADAGEDDEVIFVSAKPGSRKRSAVTSRGSVESSKRPCLPEPEQTEPLDLSLKPRPQ
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E1A protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1 by direct competition for the same binding site on RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes and of the E2 region of the adenoviral genome.  Release of E2F1 leads to the ARF-mediated inhibition of MDM2 and causes TP53/p53 to accumulate because it is not targeted for degradation by MDM2-mediated ubiquitination anymore.  This increase in TP53, in turn, would arrest the cell proliferation and direct its death but this effect is counteracted by the viral protein E1B-55K.  Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection.  Interaction with RBX1 and CUL1 inhibits ubiquitination of the proteins targeted by SCF(FBXW7) ubiquitin ligase complex, and may be linked to unregulated host cell proliferation.  The tumorigenesis-restraining activity of E1A may be related to the disruption of the host CtBP-CtIP complex through the CtBP binding motif.
What are the official names of this protein?
Early E1A protein, Early E1A 25 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1A protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PYY3_HUMAN
Sequence: MVSVCRPWPAVAIALLALLVCLGALVDTCPIKPEAPGEDESLEELSHYYASLCHYLNVVTRQWWEGADMW
What are the official names of this protein?
Putative peptide YY-3, Putative peptide YY3, PYY-III.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOK_YERPE
Sequence: MIPLQHGLILAAILFVLGLTGLLIRRNLLFMLISLEVMINAAALAFVVAGSYWGQADGQVMYILAITLAAAEASIGLALLLQLYRRRHTLDIDTVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y5383_PSEAE
Sequence: MHTLPVKTGTRPLAQVQKLIPGLLLSAALAGVAILLGRSQWLQHNGISALTLAIVLGILVGNTLYPRIAAGSAAGVGFSKQILLRAGIILYGLRLTFQDIAGVGLHGVLLDALMLASTFGLACLLGTRLFGLDRTTTLLIGAGSSICGAAAVMATEPVVRGRAEQVAVAVSTVVVFGTLGIFLYPALFQLDQDWGLLPRDPGTWGVYIGATVHEVAQVVAAGRSIGIEAADTAVIAKMVRVMMLAPFLILLSAWLARDKAHRRQHSGATKITIPWFAVGFVLVAGLNSLVSLPPALVSHVNDLDTFLLAMAMAGLGLGTHLSAIRRAGLKPLLLAALLFAWLVLGGGFLTRLALA
What are the official names of this protein?
UPF0324 membrane protein PA5383.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YE54_SCHPO
Sequence: MGNLSGWFIHCPPLQWTLDQLETMMINTIKRGKVPQHIAFVMDGNRRWARQRRMETIEGHSSGFEALKSLLKVCLKLGVKEVSAFTFSIENFKRSKYEVDMLMEIAKNSLTQITAHGDLVDQYGIRIRIVGDLSRLQPDVLETALKAVEITKHNTKATLNVCFPYTSRHEIATSVQSIVKMAEDGTITPEDIDEDIFEKNLLIKDSLPLDLLIRTSGVERLSDFMLWQCHKNTEIKFIDFYWPDFSIWKFFPMLIQYQLQNQPA
What is the function of this protein?
With nus1, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery.  Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER).
What are the official names of this protein?
Dehydrodolichyl diphosphate synthase complex subunit SPAC4D7.04c, Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific).
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: CLPP_CHLMO
Sequence: MPIGVPRIIYCWGEELPAQWTDIYNFIFRRRMVFLMQYLDDELCNQICGLLINIHMEDRSKELEKKEIERSGLFKGGPKTQKGGTGAGETGASSIQNKKSNSSSFEDLLAADEDLGIDENNTLEQYTLQKITMEWLNWNAQFFDYSDEPYLFYLAEMLSKDFNKGDARMLFSNNNKFSMPFSQMLNTGSMSDPRRPQSTNGANWNSSEQNNSLDIYSPFRMLANFEAQDYDFKQINPSLASKEEVFKLFNNTILKNGGQRNNNMSKLLTELAQRNWENKTNSQENLYKSTEKALSQRNLRKEYIKDRTLNNYSSDPFNTKGYVNAQGASTGPSPRTRGMHADGSLNYLDFYSYNDSYNDFKTAPRGKQAERAFQEEESKKVFVIINSFGGSVGNGITVHDALQFIKAGSLTLALGVAASAASLALAGGTIGERYVTEGCHVMIHQPECLTSDHTVLTTRGWIPIADVTLDDKVAVLDNNTGEMSYQNPQKVHKYDYEGPMYEVKTAGVDLFVTPNHRMYVNTTNNTTNQNYNLVEASSIFGKKVRYKNDAIWNKTDYQFILPETATLTGHTNKISSTPAIQPEMNAWLTFFGLWIANGHTTKIAEKTAENNQQKQRYKVILTQVKEDVCDIIEQTLNKLGFNFIRSGKDYTIENKQLWSYLNPFDNGALNKYLPDWVWELSSQQCKILLNSLCLGNCLFTKNDDTLHYFSTSERFANDVSRLALHAGTTSTIQLEAAPSNLYDTIIGLPVEVNTTLWRVIINQSSFYSYSTDKSSALNLSNNVACYVNAQSALTLEQNSQKINKNTLVLTKNNVKSQTMHSQRAERVDTALLTQKELDNSLNHEILINKNPGTSQLECVVNPEVNNTSTNDRFVYYKGPVYCLTGPNNVFYVQRNGKAVWTGNSSIQGQASDIWIDSQEIMKIRLDVAEIYSLATYRPRHKILRDLDRDFYLTATETIHYGLADEIASNEVMQEIIEMTSKVWDYHDTKQQRLLESRDSTTSGADTQSQN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins (By similarity).
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RUVA_CAUVN
Sequence: MIGRLRGAVAEVGEEEALIDVMGVGYLVRCGHRTLQRLPALGEETLLHIESQWSESAGLRLYGFLTREDRRAFVLLQAIQGVGPKAAMAVLDVLSPAELASAVAREDKAAVGRANGVGPKLALRIVTELKDKPITDGPVLMSAPTSSAPSAPAKPAPTGDAVAALMGLGVAEVNARRVVEAAAAELGEEATVQALIKAGLKELGR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: UPP_DELAS
Sequence: MSTLHLIDHPLVQHKLTLMRRKEASTNSFRRMLGELSTLMAYEITRDMPLQDIEIETPLETMTGKVIDGKKLVLVSILRAGNGFLDGMLNVVPGARIGHIGLYRDPETLQPVEYYFKMPSEMEERDVLVVDPMLATGNSAAAAVARLKQLNPKSIKFMCLLAAPEGVATMQKAHPDVDIYTAAVDRQLDAHGYILPGLGDAGDRIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ISCS_PSEP1
Sequence: MKLPIYLDYSATTPVDPRVAQKMADCLLVDGNFGNPASRSHVFGWKAEEAVENGRRQVAELINADPREIVWTSGATESDNLALKGVAHFYQTKGKHIITSKIEHKAVLDTARQLEREGFEVTYLEPGEDGIVTPAMVEAVLRDDTILVSLMHVNNEVGSINDIAAIGELTRSRGVLFHVDAAQSAGKVEIDLQKLKVDLMSFSAHKVYGPKGIGALYVSRKPRVRLEAIIHGGGHERGMRSGTLPTHQIVGMGEAFAIAKQEMVAENARIKALSDRFFKQVSNLEELYVNGSQTARVPHNLNLSFNYVEGESLLMSLKDIAVSSGSACTSASLEPSYVLRALGRNDELAHSSIRFSFGRFTTEEEVDYAAQKVCEAVNKLRELSPLWDMYKDGVDISKIEWAAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.