PharMolix/UniProtQA huggingface dataset:
Protein: ILVD_NATPD
Sequence: MSQQTEPDDDAALDGDEPGAYGKDERLRSREVTEGPERAPHRAMFRAMGYDDEDLSSPLIGVPNPAADITPCNVHLDDVAESALEGIDEAGGMPIEFGTITISDAISMGTEGMKASLISREVIADSVELVSFGERMDALVTVAGCDKNLPGMMMAAIRTDLPSVFLYGGSIMPGQHEGRDVTIVQVFEGVGAYAQGEMSGDELDDLERNACPGAGSCGGMFTANTMASLSEALGLAPLGSASPPAENHERYAVARRAGELAVEVVEEDRHPSDILTRTSFENAIALQTAMGGSTNAVLHLLALAAEAGIDLDIEDFDAISRRTPKIADLQPGGDRVMNDLHEIGGVPVVIRRLMEADLFDGSQLTVTGRTIEEELAHLESEHGLPTDDEIDADFLYPVDDPKEAEGAIKILTGNLAPDGAVLKVTGDDEFYHEGPARVFENEEDAMKYVQEGHIESGDVIVIRNEGPEGGPGMREMLGVTAAVVGAGHEDDVALLTDGRFSGGTRGPMIGHIAPEAFVGGPIGALEDGDHITVDIPDRTIEVDLSDSELERRLDERDDPEPAYTNGVVAKYGSLFGSAANGAVTNPGLHNDQH
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: HOA1_BURVG
Sequence: MHKKLYISDVTLRDGMHAIRHQYSIQNVQDIARALDEAKVDSIEVAHGDGLQGSSFNYGFGAHSDLEWIEAVAEVVKHAQIATLLLPGIGTIHDLKAAYDAGARVVRVATHCTEADISKQHIEYARSLGMDTVGFLMMSHMTTPDHLAIEAKKMESYGATCVYVVDSGGAMNMHDIRARFRALKAALRPETQTGMHAHHNLSLGVANSIAAVEEGCDRIDASLAGMGAGAGNAPLEVFIAAAERLGWHHGTDLYRLLDAADDIVRPLQDRPVRVDRETLALGYAGVYSSFLRHAEIAAKKYGLKAVDILVELGKRRMVGGQEDMIVDVALDLKRREARA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 1, HOA 1, 4-hydroxy-2-keto-pentanoic acid aldolase 1, 4-hydroxy-2-oxopentanoate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: PSBF_SAUCE
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MNN13_CANAL
Sequence: MIKPILGTKKIRRVICIIIGLFCILLLIGIFKHNSTNSVNNEASNFTVDFEEPSYTFPKTVLFENNNNLDDLLLAKKNNWKFQSNVYNQLFMDHSIESVLSLSFNQRCELLIRNIISQKVSWIFDPLETFEINYESEDYIQFIQQEGIKLNKKFEKIKNNLKFKTSLNNFIKDEYKIIRSKQYEQKIIDQLTILRIFNKCFIKNGSKDQNDLVDRIIQEQQKLVTKANSAANGQSELELELKLKLKLTENEKMVSELVEDYVTLGKRVYPWISQRFPFYERWNGDSYYYPPNYEEIFKDKNEPLKSERSTVRDSTSSPSIFLNQFKDASNGKGIVLSITEKHIDDTINLIRLLRALNNKLPIQIIYFNDISQSSKTKIIKAAREEINNFPKSYEKVYHGKQPSVPPSPPPPQEVWFVNIYESINPQHRNLFAKFDFKLLASLFNSFNEFMLIDADTILMKSPEFFFNHQSYQQTGAFFFKDRSPLLKRPITDGEFLIKMGPSSIDSIMFDIPMMTQYTTHRELFKGLRLYMESGLVMIDKQRRRHFNSILMMNQLKFIHPISNSMWGDKELFWLGFAINGDENYKFNNHFAAAIGQLTSNQYNKDRRTPLKSKEICSSHPGHISDEDDRSLLWFNSGFRFCHEANNIDYQEETKNNVILKFLNGRHPLEFKKYYSDPLRITHAIVPPLNKNFQKMYNYDEEPTDGWTSEPNCNKYMWCAYSSIGGRTGPEETSHKETLDGLLVEYTPEEIAYFNYLGDVWVGKY
What is the function of this protein?
Responsible for addition of the terminal mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose.  Implicated in late Golgi modifications (By similarity).
What are the official names of this protein?
Putative alpha-1,3-mannosyltransferase MNN13.
What is the protein family that this protein belongs to?
Belongs to the MNN1/MNT family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RL14_SALSV
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRNEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: LCAT_ELIQU
Sequence: EDCFTIWLDLNIFLSLGVDCWIDNTRVIYNRSSGYMSNAPGVQIRVPGFGKTYSIEYLDDNKLAGYMHTLVQNLVNNAYVRDETVRAPPYDWRLEPRHQEEYYLKLAGLVEEMYATYGKPVFLIGHSLGFCHLLYFLLLQPQGIPIMSSIKLVEEQRITTTSPWMFPSHQVWPEDHVFISTPNFNYTFSDFQRFFADLHFEDGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPHTYMYDHGFPYTDPVGIIYEDGDDTVTTHSIELCSHWQGRQPQPVHLLPLRGTQHLNMVFSNKT
What is the function of this protein?
Central enzyme in the extracellular metabolism of plasma lipoproteins.  Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs).  The cholesterol ester is then transported back to the liver.  Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines.  Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels.  Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins.  Required for remodeling high-density lipoprotein particles into their spherical forms (By similarity).
What are the official names of this protein?
Phosphatidylcholine-sterol acyltransferase, Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into blood plasma. Produced in astrocytes and secreted into cerebral spinal fluid (CSF) (By similarity).
Protein: LPXB_MAGSA
Sequence: MLIYLIAGEPSGDLLGGRLMAALKERLGEGVSFAGIGGESMRAEGLTSLFPMTELSVMGLVEVLPRIPKILRRVKQTISDIETKRPDALVTIDSWGFNGRIQAGLKARGVPVPRIHYVAPMVWAWKSGRTKTLARVLDLLLTLLPNEPEWFEKEGLKTLHVGHPVIEGAASRGDGAAFRVRHGFAPDRKLLCVLPGSRHSETAKLLAPFGETIALLARRFPDLAVVVPTVETVADEVSQAVKSWALPSMVVRGPEKYDAFAACDAALAASGTVALELAMARLPAVITYKVSPVSAFIATRFLGLSLKFVTLVNILVDEAVMPELLQDDCRPDKLAAAVEHLLTDEAARALQAAGARRALEKLGLGGESPGKRAADAVIDFIRQGKEQRNG
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RK36_AMBTC
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PURT_XANOM
Sequence: MTTLGTPLSPSATRVLLLGSGELGKEVAIELQRFGVEVIAADRYANAPAMQVAHRSHVLDMLDPAALRVLIASERPHVIVPEIEAIHTETLVALEREQGQKVIPAARAARLTMDREGIRRLAAETLGLPTSPYRFVDTAADYREAIAAVGLPCVVKPVMSSSGKGQSTLRSEADIDAAWEYAQTGGRAGAGRCIVEGFIDFDYEITLLTVRHAGGTSYCDPIGHWQQDGDYRESWQPQPMSAAALRRSQEIAKAITDDLGGWGLFGVELFVKGDEVWFSEVSPRPHDTGLVTLVSQELSEFALHARAILGLPVGAEDGGVIGQSGPSASCALLAHGNGVPVFDNVADALRDPNTALRLFGKPRVDGHRRVGVTLARADSIDAAREKARVAAAALGIQLTA
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RL14_ALKEH
Sequence: MIQMQTTLGVADNSGARQVQCIKVLGGSRRRYAGIGDIIKVSVKDAIPRGRVKKGEVYNAVVVRTRRGVRRPDGSVIRFDGNAAVLLNNQLQPIGTRVFGPVTRELRSEKFMRIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NDK7_RAT
Sequence: MKAGQQGRSCGLISPYLAPKNQSERFAFIAEWYDPNASLLRRYELLYYPVDGSVEMHDVKNRRTFLKRTKYEDLRVEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAVSKAGEIIEMINKSGFTITKLRMMTLSRKEAADFHVDHHSRPFYNELIQFITSGPVIAMEILRDDAICEWKRLLGPANSGIARSEAPGSVRALFGTDGIRNAAHGSDTFESAAREMELFFPSSGGCGPTNTAKFTNCTCCIIKPHAISEGMLGKILIAIRDACFEISAIQMFNMDRANVEEFYEVYKGVLSDYNDMVTELYSGPCVAIEIQQSNPTKTFREFCGPSDPEIARHLRPETLRANFGKTKVQNAVHCTDLPEDGLLEVQYFFKILDN
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.  Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity).
What are the official names of this protein?
Nucleoside diphosphate kinase 7, NDK 7, NDP kinase 7, nm23-R7.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: PCRB_LISMF
Sequence: MKHLFKLDPAKNLPMNDLTKLVHSGTNGFIIGGTDNVQIEAVQKLYELLGETDLPIFLEISNESMILPEADHFLIPVVLNTENSKWTHGLHQELIKEMGAFIPWKRVTAEGYVILNKDAKVAHLTEAKTDLTDEDIVAYARLAENIFHLPIFYVEYSGMYGDPEVVRKASAALSNTKFWYGGGIRSKEQAAEMAKYADTIIVGNIIYEDLEKALETATIFRKKTV
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: YQGF_PHOV8
Sequence: MSRILAIDYGKKRTGVAVTDVLQIIANGLTTVPTHQLLDFILKYVEKEPVERIIVGHPKQMNNQESENMRNIVPFVNQLRKKIPDIPVEFVDERFTSVLAHQAMLDGGLKKKDRQNKALVDEISATIILQSYLESKKYI
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSED_ECOLI
Sequence: MIRLQHDKQKQMRYGTLQKRDTLTLCLLKLQLMEWRFDSAWKFGLGRLYLG
What is the function of this protein?
A short protein whose stop codon overlaps with the start codon of downstream rpoE; a premature stop codon at position 12 results in decreased expression of ECF sigma factor RpoE, thus they are translationally coupled (PubMed:28924029).
What are the official names of this protein?
rpoE leader peptide.
Protein: RL322_LISIN
Sequence: MAVPFRRTSKAKKRKRRTHVKLQLPGMNECSNCGEYRLSHHVCPECGQYDGKDVANS
What are the official names of this protein?
50S ribosomal protein L32-2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ILM1_SCHPO
Sequence: MLFSFRAIVLFYCCMLTFAGIGFLWNPKFVVESGLVALIGASMEVKPLIVTQDNLSTLALSGLVFLILGMIYTISLLQSNFLFFSGITPIRAIFDFILTGFIYLKKEHIASNSLTFTFAFCDLMWQFWMFAAMSEERAKYLKNQKKAEELAARKAREVEES
What are the official names of this protein?
Protein ilm1.
What is the protein family that this protein belongs to?
Belongs to the ILM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Protein: HBB_SCAOR
Sequence: MVHLSAEEKGLVTGLWGKVNVDDVGAEALGRLLVVYPWTQRFFDSFGDLSSAGAIMGNPKVKAHGKKVANSISDGIKNLDNLKGTYAKLSELHCDKLHVDPENFRLLGNVLVCVMARTLGKEFTPHAQAAFQKMVLGVATALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL21_PSELT
Sequence: MYAIIETGGKQYKVSEGDTIAVEKLSVKQGEQIVFERILHLSTDGTVKIGQPYVEGCTVKGTVLSHERARKVVVVKYRPRKNYRRERGHRQWFSLVKIDKIEIEKTS
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: H2B1B_HUMAN
Sequence: MPEPSKSAPAPKKGSKKAITKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B type 1-B, H2B-clustered histone 3, Histone H2B.1, Histone H2B.f, H2B/f.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SCC2_YEAST
Sequence: MSYPGKDKNIPGRIIEALEDLPLSYLVPKDGLAALVNAPMRVSLPFDKTIFTSADDGRDVNINVLGTANSTTSSIKNEAEKERLVFKRPSNFTSSANSVDYVPTNFLEGLSPLAQSVLSTHKGLNDSINIEKKSEIVSRPEAKHKLESVTSNAGNLSFNDNSSNKKTKTSTGVTMTQANLAEQYLNDLKNILDIVGFDQNSAEIGNIEYWLQLPNKKFVLTTNCLTKLQMTIKNITDNPQLSNSIEITWLLRLLDVMVCNIKFSKSSLKMGLDDSMLRYIALLSTIVLFNIFLLGKNDSNLHRESYIMEPVNFLSDLIESLKILTIEYGSLKIEFDTFQEALELLPKYIRNGPFLDDNVTAKLVYIFSDLLMNNDIEATTNIQFQSFWDNVKRISSDILVSLFGSFDQQRGFIIEELLSHIEKLPTKRIQKKLRKVGNQNIYITDFTFTLMSMLENINCYSFCNQMKDIAPENIDLLKNEYKKQEEFLFNIVEHINDTILERFFKNPSALRYVIDNFVQDLLLLISSPQWPVTEKILSSLLKRLLSVYSPSMQVSANIETICLQLIGNIGSTIFDIKCSTRDHEDNNLIKMINYPETLPHFFKSFEECIAYNETIKCRRSATRFLWNLRLGTILILEEYTKDAKEQIITVDNELKKILEQIKDGGLGPELENREADFSTIKLDYFSILHAFELLNLYDPYLKLILSLLAKDKIKLRSTAIKCLSMLASKDKVILSNPMVKETIHRRLNDSSASVKDAILDLVSINSSYFEFYQQINNNYNDDSIMVRKHVLRINEKMYDETNDIVTKVYVIARILMKIEDEEDNIIDMARLILLNRWILKVHEVLDQPEKLKEISSSVLLVMSRVAIMNEKCSQLFDLFLNFYLLNKEAHSKEAYDKITHVLTILTDFLVQKIVELNSDDTNEKNSIVDKQNFLNLLAKFADSTVSFLTKDHITALYPYMVSDEKSDFHYYILQVFRCTFEKLANFKQKFLYDLETTLLSRLPKMNVREIDEAMPLIWSVATHRHDTARVAKACSSCLSHLHPYINKANNEEAAIVVDGKLQRLIYLSTGFARFCFPKPSNDKIAFLQEGETLYEHITKCLLVLSKDKITHVIRRVAVKNLTKLCGNHPKLFNSRHVLHLLDKEFQSDQLDIKLVILESLYDLFLLEERKSVRNTGVNSTLSSNSILKKKLLKTNRVEFANDGVCSALATRFLDNILQLCLLRDLKNSLVAIRLLKLILKFGYTNPSHSIPTVIALFASTSQYIRHVAYELLEDLFEKYETLVFSSLSRGVTKAIHYSIHTDEKYYYKHDHFLSLLEKLCGTGKKNGPKFFKVLKRIMQSYLDDITDLTSTNSSVQKSIFVLCTNISNITFVSQYDLVSLLKTIDLTTDRLKEVIMDEIGDNVSSLSVSEEKLSGIILIQLSLQDLGTYLLHLYGLRDDVLLLDIVEESELKNKQLPAKKPDISKFSAQLENIEQYSSNGKLLTYFRKHVKDT
What is the function of this protein?
Plays a structural role in chromatin and is involved in sister chromatid cohesion (PubMed:9990856, PubMed:14614819, PubMed:25173104, PubMed:26354421).  Forms a complex with SCC4 required for the stable association of the cohesin complex with chromatin, which may act by hydrolyzing ATP from SMC1 and SMC3 heads (PubMed:10882066, PubMed:14614819).  Binds to the nucleosome-free promoter regions of ribosomal protein genes and tRNA genes.  Involved in transcriptional regulation by cooperating with the RSC complex to maintain nucleosome exhaustion at its binding sites (PubMed:25173104).
What are the official names of this protein?
Sister chromatid cohesion protein 2.
What is the protein family that this protein belongs to?
Belongs to the SCC2/Nipped-B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associates with chromatin.
Protein: SYFA_DICTD
Sequence: MNEEYIEKFKEAKEKILRAQNLTELEEVKRVYLGKQGFLTQILRSIGKMPQEERAKWGRLANEWKEELESLYENKEKELKYLTLQKKLEEEKIDITLPGRRKILGRIHPINQVIEEIVMVFKEMGFQVVYGPELETDYYNFTALNIPMDHPVRESHDSFYIDKEHLLRTQTSPVQIRVMENKKPPLRVVAPGKCYRRDIPDATHSPMFHQIEGLVVDTDVTFAELKGVLTIFAHRLFGKDRKVYFIPSYFPFTEPSAEMYVECGVCKGAGCKACGYSGVLEILGCGMVHPQVFRIVGIDPEKYTGFAFGMGPDRIAMQIYGIDDIRLFYENDVRFLKQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASIP_CALGO
Sequence: MDVTRLLLATLLVFLCFFAAYSHLPPEEKLRDDRSLRSNSSVNLLDLPSVSIVALNKKSKKISRKEAEKKRSSKKEASKQKVARPRTPLSVPCVSTRGSCKPPAPACCHPCASCQCRFFRSACSCRVLNVNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: QCR10_SCHPO
Sequence: MISFFPNKPMYHVQPHISFITPERTMKTIPAFSRWAFAAVAGVFVFAMQVPKVKTTILQPIAFIGDHFKDKTPEEDKWL
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.  QCR10 has a role in CIII assembly and RIP1 stability.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 10, Complex III subunit 10, Ubiquinol-cytochrome-c reductase complex subunit qcr10.
What is the protein family that this protein belongs to?
Belongs to the UQCR11/QCR10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: URIC_HALVD
Sequence: MNYGKENVAVYRTYATPLEGVRTIPESSFDGRDNVLFGLDVRVQVEGEEFLPSFSEGDNTKVVATDSMKNFILHHAGEYDGATLEGFLEFVGSGFLDTYSQMSAVEVSADEIRFDELPVPEDDGDGYEASDLVFRVSDNESGYGSISLTRDDGTPVITDQTSGVTGLELVKVEGSSFTGYVQDEYTTLPEREDRTLYISLDIFWSYDDPEDALGEDPERYVPSEQVRDIAHVVFDEVDSNSIQDLIYQIGLRVLERYPQLASVRFEANNRTWLSVRDDLDGDASVLREPPAPTGFQQFSMDRGDLDEQ
What is the function of this protein?
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
What are the official names of this protein?
Uricase, Urate oxidase.
What is the protein family that this protein belongs to?
Belongs to the uricase family.
Protein: LEU1_SYNP2
Sequence: MNNQDDRIIIFDTTLRDGEQSPGATLNGDEKLAIARALARLGVDVIEAGFPRASRGDFDAVQRIAAEVGTENGPTICGLARATKGDIEAAGNALKPAFSNRIHTFIATSDIHLEYKLRKSRKDVLAIAPEMVAYAKTFTNDVEFSPEDAGRSDPEFLYQILEAVIDAGATTVNIPDTVGYTTPAEFGALIKGIKENVPNIDRAIISVHGHNDLGLAVANFLEAVKNGARQLECTINGIGERAGNAALEELVMALHVRRQYYNPFLGRPADSEAPLTSINTKEIYKTSRLVSNLTGLSVQANKAIVGLNAFAHESGIHQDGVLKNKLTYEIMDAQSIGLTDNQIILGKHSGRNAFRTRLAELGFDLSDNDLNKAFLRFKDLADKKKEITDWDLEAIVKDETQQPPELFRLELVQVSCGDHAQPTATITIRTPGGKELTDAAIGTGPVDAIYKAINRVVQVPNELIEYSVQSVTAGIDAIGEVTIRLRHEGRIYSGHAANTDIVVASARAYISALNRLYAALQEDVSANPAKASL
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: OOXA_RHIML
Sequence: MTLREVSTASDLREFYDVLISGAGPAGMTAALEASAAGARVAVLDENPRPGGQIYRDITRNRPERKSYLGPDYWKGKQLAEVFDRSTIDYAPRATVWSLEGRDETVAKVRNVVGVTVGGSARMIEADAVVLATGAQERPMPVPGWTLQRVMTAGAAQIALKAAGAMPSEPIVLAGCGPLLYLLASQLIDAGVSDLTVLDTAQSTFRMSVLRHMPEFLRSPYVLKGIRLLFKVKCQACVVSGVRSIAITGSERAEGVRFTTAGGEQAIPASSVLLHQGVIPSTNLTNAAGCELRWNDEQRAFEPVTDNEGRSSRQGIYVAGDGSGIAGAQAAEVSGRIAALAALCDLGLVSVTAVAARLKPLHKQARRFLRGRAFLDALYTPRSSFLAPLNPETVVCRCEEITVRKIREAIALRPPGPNQLKTFLRCGMGQCQGRLCAATVTEIMAEERKVSPADVGTYRLRSPVKPVRLAELAQLPHTARALKAVTGRDPVDHDTNETGHISCPDTDIASCGQVQRRRPTSAGIVA
What is the function of this protein?
Oxidative cleavage of octopine into L-arginine and pyruvate.
What are the official names of this protein?
Opine oxidase subunit A, Octopine oxidase subunit A.
What is the protein family that this protein belongs to?
To T-protein and to dimethylglycine dehydrogenase.
Protein: FYV4_SCHPO
Sequence: MLILKRIFIIRNFIFPFSNCRYASTVPSPRSGISNTNDFFKRIGRDTAEKVNGKFESWDGLFRKSTKTMKKEGIDVRTRKYIASQRNRFKEGFIVKPYPVMVKKNGGERRKRK
What is the function of this protein?
Involved in telomere length regulation.
What are the official names of this protein?
Protein fyv4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS41 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SMOX5_SCHMA
Sequence: MTTSTMQQLKHDGDFSDELNETSTIQFYNKVSQQRKRRKTRTTFSNCQLNELENNFNRQRYLTPTDRDRIAKHLGLTNTQVITWFQNRRAKLKREAEELERDVMALRKQKQQKFTCLSLSDHDHEETQIDDENEQGDNNNDDDGDDNDVEEDDGEEQEKNHTKYLTQPPSISNILPSSLKHFPSSTLNTLEIDNKHETLNMNLFINPFSNEKCLKRNKDLIRQQCYLFNHHINNYCTVNNDNNINNNNNNNNRKNSIDGMNKGRSIKKGNKIWCPALELEQEIH
What are the official names of this protein?
Homeobox protein SMOX-5.
What are the subcellular locations of this protein?
Nucleus.