PharMolix/UniProtQA huggingface dataset:
Protein: RNH3_LISIN
Sequence: MANTVIIVDQSTLEKMKQTYLPFSSPKLPPGAVFAAKKPGVSITGYKSRKVMFQGVNGEAEAKKWVATLPEAKTKAPSVSKGVLPANFAAKNVIGSDEVGTGDFFGPITVCAAYVDAEMMPLLKELGVKDSKAMKDPEICRIAEKIMPIVPHSVLLCPNPKYNELQKRGMNQGQMKALLHNRAIENVLKKLAPIKPEAILIDQFAEKNTYYRYLAKEPSIIREDVFFATKAEGLHLSVAAASIIARYKFVQAFDAMSKEVGIPLPKGAGPHVDVVAAEIIERFGLETLAKYTKQHFANTEKALKIAKK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR797_MIMIV
Sequence: MSDIYYQLPVEIWLQIIFFSDNINLLFVDKNFFGLIKLINDKKPIIKKIINQNYFDVLRYAIKNCIGIFGDNFMEDCLRQSFYDGQLYIADYLVDKGADIYSMGNLYFITTNETENHNNFRYVDGLNVLQGKFNKKTGFYVHKPETICQYLNHNIYLRDVYLPKGKTGFKKFKLENYYVANMIVLGKQRNLIDLDTWKYMIYHGTIITEGVIEYCRINKCTKIVDYLLDCLIETNHNIDIYTACKNGYTKLAIHYIKNSIICREIRYYIMSRGTYWTDNKSENINHEHIANLATQNGHIEILKYLVEEKYELVGNLYIIMFLACQYGHLEIIKYLVELGVDIRQGLDAFIYLLWQGSYFNILKYLLTVDSDIINIINKVDYNGWFKMYLKDPLSIDSNHYIHPYTISELKCRINSPICKPIYYLRNKSIGTIDFDDFNDIDGFND
What are the official names of this protein?
Putative ankyrin repeat protein L797.
Protein: EFTS_MYCBT
Sequence: MANFTAADVKRLRELTGAGMLACKNALAETDGDFDKAVEALRIKGAKDVGKRAERATAEGLVAAKDGALIELNCETDFVAKNAEFQTLADQVVAAAAAAKPADVDALKGASIGDKTVEQAIAELSAKIGEKLELRRVAIFDGTVEAYLHRRSADLPPAVGVLVEYRGDDAAAAHAVALQIAALRARYLSRDDVPEDIVASERRIAEETARAEGKPEQALPKIVEGRLNGFFKDAVLLEQASVSDNKKTVKALLDVAGVMVTRFVRFEVGQA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA9_FELCA
Sequence: MRCLNMIMAEPPGLITICLLGYLLGADCTVFLDHEDATKVLSRPKRYNSGKLEEFVQGNLERECMEEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQTGFEGKNCELDVTCNIKNGRCKQFCKLDADNKVVCSCTTGYQLAEDQKSCEPAVPFPCGRVSVPHISTTHTRAETLFLNMDYENSTTDYENSAEAEKNVDNVTQPLNDLTRIVGGKTAKPGQFPWQVLLKGKIDAFCGGSIINEKWVVTAAHCINPDVEITVVAGEHNTEETEHTEQKRNVIRTILHHSYNASVNKYSHDIALLELDEPLTLNSYVTPICVADREYTNTFLKFGYGYVSGWGKVFNKGRPATILQYLKVPLVDRATCLRSTKFTIYNNMFCAGFHEGGKDSCQGDSGGPHVTEVEGINFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
What is the function of this protein?
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
What are the official names of this protein?
Coagulation factor IX, Christmas factor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: L_LNYV3
Sequence: MDLWNEETTPKKNAYDSLPDYHLQNPLYAITDQLSMLKRGKRLNYRLTSSYKLMKSQSTDIKEGDPILLKEWARNWFSETELYVVDQTLSDCENRLSLDETDDLHFDTHLLRESVRMWRCEFPHDDWVRMRGMQNLLIVMNAISSRRPPPPRHTCIIPGLSKITVEGGVVLVTSSLLGFQPEGDKETTVFAADWVRAVSDVYTERFLVLSGAILGRCLSDEHYPQVLDLEFIINWGDTVLRRKGNKGFKLLKAYEALVLGVVQGKSESDFIDPDRFLRNTLNDIIDDDKDLGAYAVLLIQRLQQIDSAHHLIQLFGLHRIWGHPLVDPAKGMEKMIIIGQKDIVRETSRPEVMGVHFKKLMAQGYREKHGVYPNVKGNGELETLIKNNHDWKEVGSLDNDNHWRLLRFDKTFSIPESFNLSMIVADKSVSPTLSELKENILRKKTVMNQELRRGVLRWINHDSIDPREFLEQVNDKKFPDDHKIIGLRSKEREMNPTPRMFALMSHLMRVYVVITESMLSEHILPYFPQITMTDSQLDLTKKTYSTVKNQAAKIRRSGALYDTKTVCMSLDFEKWNGHMRKESTFHVFEALGDLFGMENLYNETYDIFKDSYFYLADGSYVPSMDAQGNFTPEPPYSFTGHKGGQEGLRQKGWTIFTVVCLDWICRKHNCTYKIMGMGDNQVLQLTMYTYRVDASGKATERGREDMRRVLFGLFDDLLDVFSDLGLPLKPLETWISEDLFVYGKYPVLKGVPLSMDLKKIMRIFPFSNQETMTIENALNTIAGNAQAATQAAPFLGVSYLVGIFMISLCSHDMLVYHPLIAKGLREVLRENRTWGLKFKGAHQVKTDIKGEMVDETNLRRLMMNVPRILGGYVSFNLYGLMMRGFPDPVSLAYSQLFSWGVPTGGSDQRDYMLRWLKPIFMPERSMRLLVEDVSSVNLLAPVTPTAGLRRVVEQYLTDGRVIKNAEFRDLMMSRDNELEDVISEHLCSGEHLHIRLIHDIMESTIFGYVKSITSKVTKSSTIVSLAIGKAKGDPLTRLMSDEENYFRFFMWRSVINPHYDIPACPTDLAKQVRRIGWGKELIGVTVAYPWSFLKKTDCYESGCLCTCDDGFISLFLPDSPVTPQEWDRSIGKNPPYLGSMTKEKVVISTGSKVYSGEPLVRRPINLMRVIGWFVPEESETAKIIMSCVSAVSDVNPLIFKGMTEGTSGSEIHRFRDTSLKHGALCSSNYLYSTRYHVSTDTFTRYAKGAQNYDMLFQANLCAIVETTHQYVLKTNQSKEPQRKTHHYKQTCYSCINPLDESFYDVKSSKLSQLIPSKKTNKYLYVPEAKISMTLEHVPAKSWEFGTLSSDGFDQLSVNLRLQWLTDAVADNVVIDILNPAGEESYTTTSLMDIKEHNRLFYLTIRPRDFYDQLCNRILILAEWRCMSLSDWKTPTTEAISRAAEAIIGDTPISRWYGVTGFFSWPSSMERYYVYPEIQEPDSIPVTALSACRSVRNSLLGLLGSSRKFRGRNTRIFSEDAKASKLSLKLMVYDWVKKKKKCRACHREIGIMSAHQLSSTLPNSIICPKGHYVTQGLKDLDIMRSRVTLDSLRKCCSSDEIPTEPMEKKITEWAPLTSTTCRTLFDSSSMRSELIPYSPTGIESSINVQPIPKSDLYKLISLPTNAMYKYMEVISRNIEGIMNCKTAFVTGNGLGGTSKVLSNMWPGRIITSTLLDTGDAIPQVYPNCDKGSSSYARGTVISDLMVTRVNDVNHLLWGEDWKPVFQSYETDLCISDIEINGELNGESRQTMIATVTMAHDWKMVIMKDYIYNMREMENRLSILLPVFKSLELITCNSRQRVMPEVWWIMKARRSSGKLLGYHRSVIRQIWDGVKEGINTADWAMESVFSEINRTIASTADMIAMTIRLKAFFSLPIVGSVLPYKGSYTRLLGYLQRGKKPEDISLITSDDGKRLYLSDYEKVRSVLFGLAVGMCSSATERDRMLDESEYWAIDWIPSGPHIWLPYLFKGVERSTLIHVYDYIPMLTLIMKRERLLFKSSSDIIEFKYTNNRDSCCFPITKTAKIKFNIK
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the rhabdoviridae protein L family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=L and P are packaged asymmetrically towards the blunt end of the virus.
Protein: SECA_AMOA5
Sequence: MLKLFTKLFGTKSERDLKSIRPYVEKINLEYEKLVSLTNDELRKKTDSLKQYIKVETQEFIGELEIRERQLEATTQLTPKEVEDLYIQISRIKEQYNTQLEKVLLDILPQAFAIVKETARRFKENEQLIVTATGYDRELAITEKHIDIEGDQAIWKNQWEVTGHLLTWDMVHYDEQLIGGVILHKGKIAEMATGEGKTLVATLPTFLNALVGKGVHIVTVNEYLAKRDAAWMKPIYQFHGFTVACIEETSPYSAARREAYQADITYGTNNEFGFDYLRDNMASQQEEVVQREHHYAIVDEVDSVLIDDARTPLIISGPVEKGNEQEYITFNPRIKRLYEAQKQIVNQFLQEAKSQMVAGKNDEAGLPLFRAYRGLPKYKPLIKYLSEPGVKQLLHKTENYYIQDNSRMMPEADEPLLFTIDEKHNTVELTEKGLEYITQQGEDPDFFILPDTATAVGEIESDAGLDNLEKEQKKQILAQEYAIKSQRIHAVQQLLKAYALFEKDIDYILVDGKAKIVDEQTGRVLEGRRYSDGLHQAIEAKEEIKIEKASQTYATITLQNYFRLYHKLAGMTGTAETEAGEFYDIYHLDVVVTPTHKPVVREDKDDKVYKTVREKFNAIIEEITVLANQGRPVLVGTTSVEISELVSKMLNLRKIKHQVLNAKHHQKEAEIVAEAGKPGTVTIATNMAGRGTDIKLSPEAKAAGGLAIIGTERHESRRVDRQLRGRAGRQGDVGSSQFFVSLEDSLMRLFISDRIAKIMDSLGLKEGEMIQHSMITRSIERAQKKVEQNNYAYRKRLLEYDNELNKQREIIYRRRRDALLGHRLGAEVNAMLFEVAKSSVMQQGVKANYHVLATKFSYITGTLPPITEEEFHTYDIQKITDIIYQAFLSSYMNRLAVFKEQGIAVQMNLPDHIADIRAEYLSFSFSDSERRLEVPVKIADFMDNAGEAILKSLERVAIIYYLDRYWQEHLRYMDELRHSVQNASYEQKDPLLIYKFESYALFSTMIARANESIITYLLKANLLLYKASDEKPKMVEKNKRIELEESKQDIISLLRERASNSSEEILKPQPIKSQKIANRNERVTVQYEDGTIKENVKFKSVEEDIANGKCILLETR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: LEU1_YERPN
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDIMEVGFPVSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHIESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAITAGATTINIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQVEGTINGLGERAGNCSLEEVIMAIKVRHEMLGVHTNINHQEIYRTSQLVSKICNMPIPGNKAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPESIGLKEVQLNLTSRSGRAAVKHRMEEMGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEYYRLDYFSVQSGSSVMATASVKLVCGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSAKGQGKDALGQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLNNIWRAHQVEKEKQRLQQNNQEMV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: SECB_RICRS
Sequence: MSTINTDTNETMPHISVNAQYIKDLSLENPSAPSSLAALDQRPQIDLSLDINITNLSEESFYEVELNIEAIARNEKYKLFQVELKYAGVFNLINIDSEQHPVLLSVHCPAMIFPFARKIIASCTQDAGFQPLMIDPIDFGALYHKKMSEHQN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNE_SALPC
Sequence: MTPLSSPLSQYWQTVVERLPEGFTETSLSVQAKSVLTFSDFALDSVIAHPEWLAELESASPQADEWRHYAGWLQEALAGVCDDASLMRELRFFRRRIMVRIAWAQTLSLVDDETILQQLSHLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALHLLPENDVAQLRVAYLFLRRLENLLQSINDEQTQTLPADDLNRARLAWGMKAENWPQLVGELTDHMANVRRVFNELIGDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQVLTLIADFRKELDKRPIGPRGRQVLDQLMPHLLADVCSREDAAVTLSRITPLLAGIVTRTTYLELLSEFPGALKHLIMLCAASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELRQYLLRVPEEDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWTQMVARYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEAWTWEHQALVRARVVYGDPQLTSQFDAVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDNVRILELLAQNGIMDEHEAQALTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: ATG11_CANGA
Sequence: MEYRCLDCTTGDTIAVDLKVFLDLKEFKSYLSNKWGVPRAQILLLYPFGIKLKDSNFRHASDLESPEIYVYDRRLFSLTNEPHTGADAHADSDADADADTADVEQQAAQLLDSLLEQRRHPQLQDDLIRPIPSPLEDLKIADGISHRTAVSMLTTNLGWLSALEIDVNYYSSISDKCKEDTQSLARCLGTCEQYLGLYCYDVERLYNSNVVFLDQLHENSLQSRWKECYKNTLTKLAGLNGYLSQYVDEAKQIEKEVTLKSLDGKVNSKLKQIKKELDSYADQRKSIQNEIENLKNIKDMKNDDNELHEMQKSFDSIADTVRKASRDILDKDDALFTDEYITQEVVPVMIDIQKKVKTLLTVSQALYENMHELLTHKRNFQIQIIVKLGQIAWIQLQISELKQYLLNDCNADLTLYKDLEVEFAQIEDYPLIYGLYLVEKYRRQVWKCGMAKNMISISNDIKERSAAELTTRKNWYKNFGELSKPFNEDLTKYNDLDEISKLMNSDSQFLKEKFIQDLRNEQRKLEDVIKSFIKNMHDLGLSKETTQVLEQSFKEASNSNICSQIDVTYDHRRINNENDLIKRYKIRIRKLESLLHEQGYSSISKWPSGVLNHTDRPNYFADNVSPAGRSLLVSSSALLGLEPSASLKTDAEMFDLKKEIGDLSEKVTALEKDNKLKTDQLKITHSKLIDIEVEKAAFRETLNHLNKELARLTVNEEDQTNLLKEERLRFKKEMTSVTVVNQNLMNNLDALQKTFEDVELENAHLKSKLKELQQRQDQLIEDSANEKLEIKSKYEKLIKEKDENMGQAFAVTNKAISGEQNKTESDIIHSSPYPEAILHLRTELFDIFSTNIYILENIGLLLTETSAGKFEIKRVKGLKKGLSQSLLDESAQISPIDGVINSVVYKNIRAQYEQLPNDNNISNCELFISSVKKIYENKLFESAVINRFKDIETLAKRLTKENKSKRILIDLYQNERLAVKDFRVNDLALFLPTKEALSETKSLSSSMASSFSSVDLSTPISGANNNITASRKSLHKPNVKHPWAAFTAFNESSRYFLKDENMVTDNKEWFIGKITDIQRQVVENISTNNPFKLPKDTVWYLISAEMISID
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy.  Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation.  Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation.  Required for the Cvt vesicles completion (By similarity).  Contributes through its regulation of pexophagy to survival during engulfment by host phagocytic cells during infection.  Through its function in autophagy, acts as an important virulence factor that supports the viability of C. glabrata in the phagosomal compartment of infected innate immune cells.
What are the official names of this protein?
Autophagy-related protein 11.
What is the protein family that this protein belongs to?
Belongs to the ATG11 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.
Protein: YIDC_ANAD2
Sequence: MGPDNRRILLATVLSVGILILWQVIFPTKKAPPKPAHPPAAEVAKPAAPASPAPGAAAPAVPAPPPDAPEETVTLAGKGFEATLTTYGGALKSLRLEGDKFRKQEKDREVQIDLVHVTSGQPYPLSLSASPELGGAVDVAADPGARAPMRIVANDASSVTFEGRVGNLAARKTFRVTGKPYELALDVELSGGAGSGTVGVLYPAFMPPDTKSGGIFSGPPLDFVRPVCRAGTTTERFDLAKEGAPEKLEGQVSWAGVDQHYFVAAVLPAEPIGTCTFVRGPVKGAGLAAVAVPVEGGARKLSLTVYAGPKDLDTLRGYGRGFESAIDYGAVAKFFALFARGLLYVMRWLEAIVRNWGVAIILLTVLVRLVLFPLTYKSMQSMNEMRKLQPEIEKLKAKFGDDREKMNLAVMQLYQKHKVNPLGGCLPMLLQMPVWFALYAALQTSVELYREPFLWMKDLTAHDPYFILPIAMGISSFVMQKLSPQPADNAQAKMMLYFFPGFFTVIMLFVPGGLTLYIFVNNLLSIVQQQLMMKHQQAAPAPAAGK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIP_RHIMI
Sequence: MVLKQRANYLGFLIVFFTAFLVEAVPIKRQSNSTVDSLPPLIPSRTSAPSSSPSTTDPEAPAMSRNGPLPSDVETKYGMALNATSYPDSVVQAMSIDGGIRAATSQEINELTYYTTLSANSYCRTVIPGATWDCIHCDATEDLKIIKTWSTLIYDTNAMVARGDSEKTIYIVFRGSSSIRNWIADLTFVPVSYPPVSGTKVHKGFLDSYGEVQNELVATVLDQFKQYPSYKVAVTGHSLGGATALLCALDLYQREEGLSSSNLFLYTQGQPRVGDPAFANYVVSTGIPYRRTVNERDIVPHLPPAAFGFLHAGEEYWITDNSPETVQVCTSDLETSDCSNSIVPFTSVLDHLSYFGINTGLCT
What are the official names of this protein?
Lipase, Triacylglycerol lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
Protein: RL6_THEAC
Sequence: MINWKEARSIKIPDGFKVSISGTTVTISYGGKTISKNFANNYVKLVEDGSTIKINASKNNSMVRGIVGTWASEINNMIKGLKDGFQYEMKIDYSHFPMRVSVKGKTVVIENFFGERSPRTAEIVGDTTVTVKGDRVYIAGISKKDVGETAANIERSTIIKGFDPRVFQDGIYLISKGE
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: COBQ_CLOPS
Sequence: MKYKSIMLLGTASSVGKSTVAAAFCRYFKKKGYRVAPYKALNISLNSFVTKDGDEIGRAQVVQAEACEIDPKEYMNPILMKPSAGFKTQVIVRGKVHCTMDAYKYKELNKYLKEKAKEAYDDISNDYDLIVLEGSGSCAEINLRETDIANMHTAKMADADVILVSDINRGGVFASIVGTIMLLTEEERKRVKGVIINKFRGKREFFEPAMRQIEEIIKIPVLGVMPYFDLDIEEEDSASIKLRKGNGKGIDIAIVRLPHMSNFTDFNSLGRIKDVCIRYAENPKDLENANMIIIPGSKNTIDDLIYLKESGFKEALINESSKGKLIFGICGGYQILGEKIIDSLGVEGDIREEEGLGLLNIVTSFNKEKTTKQVVAFDLEGNEVSGYEIHNGESVPTAKENIWIKEQNGNVLGMKNKEQNVFGTYIHGIFDEGDFGEKLINKLKKELNIEESNDVNYKDYKMSQYDKLCELLEENIDMAYVENLIRY
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: ARND_ECO45
Sequence: MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQAHSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIEAKEAFHLRYNSDCRGAMPFRPLLESGTPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRIQRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSGTLPLGQVVRGNIAGREGWLGCQQIAGSH
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: PKNK_MYCTO
Sequence: MTDVDPHATRRDLVPNIPAELLEAGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDNLERFLREQRAMGRLSGHPHIVTVLQVGVLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLAGALEAAHRVGTLHRDVKPGNILLTDYGEPQLTDFGIARIAGGFETATGVIAGSPAFTAPEVLEGASPTPASDVYSLGATLFCALTGHAAYERRSGERVIAQFLRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGEELRDVQRRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLRLPRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEFLSENVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAMLEEAEHRGLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAENGYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSMVVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQADLRAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAICRFEFAEVYPLLDWAAPYQEMMGPFGTVYAQCLRGMAARNRLDIVAALQNFRTAFEVGTAVGAHSHAARLAGSLLAELLYETGDLAGAGRLMDESYLLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPRLAARINNERIRLGIALPAAVAADLLAPRTIPRDNGIATMTAELDEDSAVRLLSAGDSADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA
What is the function of this protein?
Key microbial factor involved in regulation of early and late events in tuberculosis infection, and in host-pathogen interactions.
What are the official names of this protein?
Serine/threonine-protein kinase PknK, Protein kinase K.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Secreted, cell wall. Note=Probably attached to the cell membrane through interactions mediated by its C-terminal region. May be secreted during infection (By similarity).
Protein: FLR4_CAEEL
Sequence: MPINYNRNAVELKLSSQLLQWLDQRLPLGDPMRIPSIDSYKYIQDLGKGRFGTVCKFSNGNTFETVKKVDLTIFNHWTQSETKVSNRLDTFLYEFRHLHKVTNDNNRIVNFLGIYADSNQMYIMSEYLPRGSVKDLLVKETLGEDTAIKYLMETVEALDYLHNLSPPVIHRDIKAANLLITSNDSIKLANFGLVRDLAVDGFGIAIASEITLDFRATLLYVAPEVLSSALGPGNRNAYELPADIWALGCTFIEMLLKRPPHFEYFGHIDEIPKVLLGYAKSEDGKVLPYTSEVLVPSSSNCVQKIVDLVFIKSPEHRPNTHKLRIQIKKILDDDSESEEETDISHPISNSNTDSSTAISHNHSNDRKVGRAGTCLPIESMEYAAVRKELKKRSKPKSNNIMQIFVASGYYLSRILYFLNILTRSICYLLLFLSLGITALGSFLLISYFVVRFVRYLIAINCNCDLMQPQYLIISGILIVLMFALLFSCCMVALGEYKFRMANQTLDGSKFYLPRPQKSAVLCGITVITGKEDAKDTAQNMEEEIHLTPSVRRNHDDYYYDESSGPANEEN
What is the function of this protein?
Probable serine-threonine protein kinase involved in the control of defecation rhythms.  Required to increase the length of defecation cycle period.  Acts in a cell-functional rather than developmental aspect in the regulation of defecation rhythms.
What are the official names of this protein?
Serine/threonine-protein kinase flr-4, Fluoride-resistant protein 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: CYSM_MYCTU
Sequence: MTRYDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIEQAEADGLLRPGATILEPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIFSAAEGGSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADLPEITHFVAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYGEGVYALRNMDEGFVPELYDPEILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVADAGWKYLSTGAYAGSLDDAETALEGQLWA
What is the function of this protein?
Catalyzes the formation of a covalent CysO-cysteine adduct via a sulfur transfer, using the thiocarboxylated sulfur carrier protein CysO-COSH as sulfur donor and O-phospho-L-serine (OPS) as sulfur acceptor.  Can also use sodium sulfide as sulfur donor in vitro, albeit with less efficiency, but not thiosulfate or thio-nitro-benzoate.  O-acetylserine (OAS) is a very poor substrate in comparison with OPS.  May be of particular importance for cysteine biosynthesis in the persistent phase of M. tuberculosis.
What are the official names of this protein?
O-phosphoserine sulfhydrylase, OPS sulfhydrylase, CysO-thiocarboxylate-dependent cysteine synthase, Cysteine synthase B, CSase B, O-phosphoserine-specific cysteine synthase, [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: MUTL_CLOBM
Sequence: MRKINLLDLETTNKIAAGEVIERPFSVVKELVENSIDAGAKNITIEIEDGGQKLIKIIDDGEGIYPIDIKNAFLPHATSKINSIEDIYKISTMGFRGEALASISSVSKTKLKSRVDSYNFGKEIYIEGGKIEYLKDTGCNVGTTIEVSDLFYNVPARLKFLKSARSDSSSISDIVNRFILAHPDISFNLINKGKQSIKSYGTGNLKDSIRCVYNKTISENLINFESHKDIISVYGFIGKPEISRKSRTNQSIFVNKRYVKSKFITAAVENAFKSFLTVNSYPFFVIFIDIFPEYIDVNVHPTKSEVKFKDERAMFKTIFDAVHEAIKGELKESFTNFFNKEDINIYDSEKSIAETIKLEKEEVQIPIDLNSNNKIDIFGNNINKLPTNTEVLKNIGIKEKNILENNDNFYTSKQNEIYYTNKNDEYLNSCNKDDYSKIEKPLQKGNKNPDALYLNEHNTNSSSINIKENKSNNFYVDMKIIGQFNNTYILIEKDKELYIIDQHAAHEKVLFEKFKSEIEKGYVISQILLSPVVIELSEDEFNIYEENKDIFKNSGFAVENFGESTINIKEVPLILGKPNVENLFMDILYNLKNMKSKETSTIKYNAIATLACKSAVKANDNLKEEEIKKLIEDMLILNNPYTCPHGRPTMIKFTLKDLEKKFKRIQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.