PharMolix/UniProtQA huggingface dataset:
Protein: NSP1_ROTS1
Sequence: MATFKDACFHYRRLTALNRRLCNIGANSICMPVPDEKIKGWCLECCQIADLTHCYGCSLPHVCKWCVQNRRCFLDNEPHLLKLRTVKHPITKDKLQCIIDLYNIIFPINDKVIRKFERMIKQRKCRNQYKIEWYNHLLLPITLNAAAFKFDENNLYYVFGLYEKSVSDIYAPYRIVNFINEFDKLLLDDINFTRMSNLPIELRTIMQEYFQLSRLPSSKLKQIYFSDFTKETVIFNTYTKTPGRSIYRNVTEFNWRDELELYSDLKNDKNKLIAAMMTSKYTRFYAHDNNFGRLKMTIFELGHHCQPNYVASNHPGNASDIQYCKWCNIKYFLSKIDWRIRDMYNLLMEFIKDCYKSNVNVGHCSSVENIYPLIKRLIWSLFTNHMDQTIEEVFNHMSPVSVEGTNVIMLILGLNISLYNEIKRTLNVDSIPMVLNLNEFSSIVKSISSKWYNVDELDKLPMSIKSTEELIEMKNSGTLTEEFELLISNSEDDNE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: ISPH_DEHM1
Sequence: MKVECASNIGFCFGVRRAINILEKTAAEKGGVETLGALVHNQQVLNRLSGMGVRVVKNIEDISGRTVAISSHGVGPLVLDELKSKGLEVVDTTCPFVKRAQVAAKRFHDAGFFTVIYGDVNHPEVKGIMGWAGGDGLATLNPQGLVDVPDVSRYIGVLSQTTQIPTGFTSFVKNVIDQALVKDAEIRIADTLCHDIRERQTAALELAGRVDLMLVIGGHNSANTRHLLDLCKTVSNTYLIETASELQTGWLRGVNRIGITSGASTDETTISEVCSYLGSLSAGT
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: KCNJ4_RAT
Sequence: MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEPSPSGPTAGGPGGNGGGAAPTAAKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMPRPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEETGIIRMLEFGSHLDLERMQAATLPLDNISYRRESAI
What is the function of this protein?
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  Can be blocked by extracellular barium and cesium (By similarity).
What are the official names of this protein?
Inward rectifier potassium channel 4, BIR11, Brain inwardly rectifying K(+) channel 2, Inward rectifier K(+) channel Kir2.3, IRK-3, Potassium channel, inwardly rectifying subfamily J member 4.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Postsynaptic cell membrane; Multi-pass membrane protein. Note=TAX1BP3 binding promotes dissociation of KCNJ4 from LIN7 famaly members and KCNJ4 internalization.
Protein: MNMG_ECOLU
Sequence: MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREASGEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_SALPA
Sequence: MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDVRVLLPGFPDIRRGIPDAHVVSRRDTFAGKISLLFGHYNGVGIYLIDAPHLYERPGSPYHDTNLYAYTDNVLRFALLGWVGCEMACGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAKHMDDIELPWSFFNMHGLEFNGQLSFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLRQRHLEGRLSGILNGVDEKIWNPESDLLLASRYTRDTLEEKAENKRQLQIAMGLKVNDKVPLFAVVSRLTNQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEHPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDSSLENLADGIASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: MUTS_XANC5
Sequence: MQSTDTKEKNKNASGAVEHTPLMKQFFAAKSDYPDLLLFFRMGDFYELFYDDARKAARLLDITLTQRGSSGGAPIPMAGVPVHAYEGYLARLVALGESVAICEQIGDPALAKGLVERKVVRIVTPGTVTDEALLDERRDTLLMAISRSKHGYGLAWADLAGGRFLVNEVDSADALEAEIARLEPAELLVPDEDNWPDFLRGRTGVRRRPPWLFDADSGRRQLLAFFKLHDLSGFGIDDKPCATAAAGALLGYVEETQKQRLPHLTSIAMEVASEAISMNAATRRHLELDTRVDGDTRNTLLGVLDSTVTPMGGRLLRRWLHRPLRLRDVLLQRHHAVGTLIDAGADADLREAFRALGDLERILTRVALRSARPRDFSTLRDGLALLPKVRTILAPLDSPRLQTLHAELGEHDATAHLLISAVAETPPLKLSDGGVIATGYDAELDELRRLSTNADQFLIDLEQRERASSGIATLKVGYNRVHGYYIEISKGQAEKAPLHYSRRQTLTNAERYITEELKSFEDKVLSARERSLSREKLLYEGLLDALGTELEGLKRCAGALSELDVLAGFAERAQALDWSQPELDHAPCLRIEHGRHPVVEAVREQPFEPNDLDLHSDRRMLVITGPNMGGKSTYMRQNALIVLLAHIGSYVPASRAVIGPIDRILTRIGAGDDLARGQSTFMVEMAETSYILHHATPQSLVLMDEIGRGTSTYDGLALADAVARHLAHTNRCYTLFATHYFELTALADESHAGGASGIANVHLDAVEHGERLVFMHAVKDGPANRSFGLQVAALAGLPKAAVTQARRRLVELEQRGGESHSAQMAPTALDAPQQFGLFTAPSSAAQEALQALDPDELTPKQALEALYRLKALL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MSHC_MICLC
Sequence: MKSWSTPAPPTVPSRPDRLRLHDTATGRTRHPGNDGRRASLYVCGITPYDATHLGHASTYVAFDLLHRYWRAAGLEVAYVQNVTDVDDPLLERAEATGVDWRALAEEQTDLFRADMAALEVLAPDHYVGATEAVGLVVDAVETMLAAGRAYRVPGGDGEPEGDVYFDVRSAQSATDWRLGQVSAMDLDEMAAVFPERGGDPDRPGKRDPLDPLLWRVHREGEPAWDGRSLGSGRPGWHIECSVISRAHLPAPFTVQGGGSDLRFPHHEFSAAHATAVDGLPLAHTYAHTGMVALDGEKMSKSLGNLELVSRLRARGVEPVAVRAAILAHHYRSDWEWSEQVLTDAQARVTRWRAALDGPHAAAGVAVLDAVHAALSDDLDAPRALEALDAWAAGTLPGLVETAADPVPVVDVVAALLGLRLR
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: RSMA_HAEI8
Sequence: MNSKKHLGHTARKRFGQNFLHDTSVIQGIVAAIYPQPNQFLVEIGPGLGALTEPVGELVDHLTVVELDRDLAERLRHHPFLHQKLTVIETDAMQFDFDELYTTENLAEKGQKLRVFGNLPYNISTPLMFHLFKYHDVIQDMHFMLQKEVVKRLCAGPNSKAYGRLTIMAQYFCQVMPVLEVPPSAFKPAPKVDSAVVRLIPHKELPHPVKDLYWLNRVCSQAFNQRRKTLRNALSTLFSPENLTALGIDLNARAENLAIADYARLANWLADNPPADVNNDEILDSEE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_STRS7
Sequence: MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIVDYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNTVRLNGYTLEAEAGANLIETTKVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAREMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRQLKQPLEFPSCGSVFKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEELIAHVIKTVEQTSGVRLEPEVRIIGESL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_GRATL
Sequence: MSRYRGPRLRISRRLGDLPGLTRKISKKLSPAGEHGQQLRKPSEYSLRLEEKQKLRFNYGLSEKQLSKYIKIAKKVTGSTGLILLQILEMRLDNVIFRLGLSPTLPAARQLVNHGHILINKQKVSICSYQCKPGDIIDVQAKDSSQNLVKRYLSFPTLVGIPNHLELNTKTLNAKINAIVERESVALQMNELLVVEYYSRK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL2_BURVG
Sequence: MAIVKVKPTSPGRRAMVKVVNKDLHQGKPHAALLDTQSSTAGRNNNGRITTRHKGGGHKHHYRIVDFRRTKDGIPAKVERLEYDPNRSANIALVLYADGERRYIIAPKGLTVGQQLMSGSEAPIRAGNTLPIRNIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAREGVYAQVRLRSGEIRRVHIECRATIGEVGNEEHSLRQIGKAGANRWRGIRPTVRGVAMNPVDHPHGGGEGKTAAGRDPVSPWGTPTKGYRTRSNKRTTTMIVQRRHKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: IPP_HUMAN
Sequence: MANEDCPKAADSPFSSDKHAQLILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESSKDVVPILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQIDPLNCIGIFQFSEQIACHDLLEFSENYIHVHFLEVHSGEEFLALTKDQLIKILRSEELSIEDEYQVFLAAMQWILKDLGKRRKHVVEVLDPIRFPLLPPQRLLKYIEGVSDFNLRVALQTLLKEYCEVCKSPKENKFCSFLQTSKVRPRKKARKYLYAVGGYTRLQGGRWSDSRALSCVERFDTFSQYWTTVSSLHQARSGLGVTVLGGMVYAIGGEKDSMIFDCTECYDPVTKQWTTVASMNHPRCGLGVCVCYGAIYALGGWVGAEIGNTIERFDPDENKWEVVGNMAVSRYYFGCCEMQGLIYVIGGISNEGIELRSFEVYDPLSKRWSPLPPMGTRRAYLGVAALNDCIYSVGGWNETQDALHTVEKYSFEEEKWVEVASMKVPRAGMCVVAVNGLLYVSGGRSSSHDFLAPGTLDSVEVYNPHSDTWTEIGNMITSRCEGGVAVL
What is the function of this protein?
May play a role in organizing the actin cytoskeleton.
What are the official names of this protein?
Actin-binding protein IPP, Intracisternal A particle-promoted polypeptide, IPP, Kelch-like protein 27.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RNFT1_DANRE
Sequence: MKLRAQFDRGTYSESKGSFKLRDSLDPMQPEPSSREGNGLSLTLQPELLARMPGAGSSSGTETGEDVRVPMGSSSGSTNGRGATSRRMRTASHSHSHTHGHGHSHEHESDSGESDLESGESSSSISELRYLLRWLKKSLPFIVILCAKLVIQHALGLAVAVGLFTTFMYVNKSIQTQVFLHDRRTNLHCAWLLLFLTSSSLLVFYTFHTQSLYRCLFFANATIDYHNFWEVLWSVGVTNFILKFIFMGFKCLILLVPCPLMTYRRRGQWYMLIEEVGQLYQVIAPVPLWFRYLVSYDEMDTSVGLTLGILLALLYLIMKLLALYGLSGSLQKTLRTFFSPEVNGAPASPAQIREAGDICPICQADFKQPRVLVCQHIFCEECIAQWLNQERTCPLCRTVITDKVHKWKDGATSAHLQIY
What is the function of this protein?
E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation.  Protects cells from ER stress-induced apoptosis.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNFT1, RING finger and transmembrane domain-containing protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: KDPB_ECO8A
Sequence: MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGAMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKKTAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHIEANGGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFAQLRQMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPG_BUCAT
Sequence: MTSTKEIKNKIVSVTNTKKITKAMEMVAVSKMRKTEERMRSGRPYSDIIRKVIDHVTQGNLEYKHSYLEERKTNRIGMIIISTDRGLCGGLNTNLFKQVLFKIQNFAKVNIPCDLILFGLKSLSVFKLCGSNILAKATNLGENPKLEELINSVGIILQEYQYKRIDKIFIAYNKFHNKMSQYPTITQLLPFSKKNDQDASNNNWDYLYEPESKLILDTLFNRYIESQVYQSILENIASEHAARMIAMKTATDNSGNRIKELQLVYNKVRQANITQELNEIVSGASAVSID
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CLPP_LEUCK
Sequence: MWPGVIEQTANGRESYDLPSRLLKDRIVLVQGEVEDSMATSIVAQLLFLEAQDPTKEISMYINSPGGSVTAGLSITDTMNFIKAPVTTIVMGLAASMGTIIASSGEKGHRFMLPNAEYLIHQPMGGAVGGTQQTDMAIIAEQLTKTRDKLNKILADASDRDLETIARDTERDHWMSAEETLAYGFIDGILTKSGEKPTTK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_BACAC
Sequence: MARIAGVDIPRDKRVVISLTYVFGIGRTTAEKILAEAGISEETRVRDLTEDELGRIRDIIDRIKVEGDLRREVSLNIKRLMEIGSYRGLRHRRGLPVRGQNSKNNARTRKGPRRTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL34_STRM5
Sequence: MATKRTFQPSNLKRKRDHGFRARMKTADGRKILSRRRAKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RS11_METM7
Sequence: MSQKWGLVHIYASYNNTILHVTDLTGAETIAKVSGGMIVRNQRDESSPYAAMQAAFKIADLMRDKGIDQVHVKVRATGGQKSKNPGPGAQAAIRALSRAGIRIGRIEDATPIPHDGTTPKRKNR
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DNLJ_CROS8
Sequence: MESIEEKLTQLRTTLRHHEFLYHVMDAPEVPDAEYDRLMRELRALEEAHPELVTPDSPTQRVGAAPLTEFSQVRHEVPMLSLDNVFDEASFLAFNKRVQDRLKSTDALVYCCELKLDGLAVSLLYENGLLVRAATRGDGTTGEDITLNVRTIRAIPLKLRGDNIPARLEVRGEVFLPQAGFEKINEEARRTGGKVFANPRNAAAGSLRQLDPRVTAKRPLTFFCYGVGLLEGGELPRSHMERLQQFKAWGLPVSDRIRLVKTPEEVLAFYHQVEADRPTLGFDIDGVVIKVDSLELQEQLGFVARAPRWAVAFKFPAQEQMTTVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIARLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETRPVVFPAQCPVCGSDVERVEGEAVTRCTGGLICGAQRKEALKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFRLTAGKLTGLDRMGPKSAQNLVNALEKAKETTFARFLYALGIREVGEATAAGLAAHFGTLEALINASIDDLQKVPDVGIVVATHVFNFFEEESNRAVIRDLTEEVGIHWPAPQVVKAEEIDSPFAGKTVVLTGTLSQMSRDDAKARLAALGAKVSGSVSKKTDLLIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MOBA_BACC4
Sequence: MSKYAGIVLAGGMSSRFGEPKALAIWKGTTFVEHIVKVMGNTLQDIVVISHTDIKERVEQFVQVPVIEDIPHYKGNGPLAGIVSGMEYIEADWYAIMPCDAPNVSHEWFTILLEQTNNEYDAVVPIINGRKQPLLAAYHNRVKEKIYALLQEEKRSMGQLLSQCNVKYVSGEDVQANADWFINVNTKEEYGQAQKDLSNE
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_ROUAE
Sequence: MTLVYMNMALAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFVTMAVTILNSHLILANMIPIILLVFAACEAALGLSLLVMVSNTYGVDHVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: THII_TREPS
Sequence: MVNGSTQYLAHVGELSLKKGNRRQFEVQLERNLTLMLRSINPHVTVRAGRLYLSVPASFEAQTTAEQALSCLLGITGWAAATACPKTMEAITRCAHAEATLAAREGKRTFRIEARRADKRFCRTSSEIAREVGAVIHQSGALSVDLHYPDVVIFIEVREREAFLYGARRRGLRGLPCGVSGRGLLLLSGGIDSPVAGYRMLSRGMHIDCLYFHSYPYTPPEAQKKVEDLAKVLARYGLSTTLTVVSLTDIQKQLQTHAPAPSLTLLLRMCMMRIAEHVAREQRARCLITGESLAQVASQTLENLTVTSACTHLPIFRPLIGADKEDIIRTATEIGTYAISIRPYEDCCTLFAPKHPVLRPEVEEMQKQYQSLMLGPLLEDAFRTRKRTRIYGNYGVQESGE
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPSB_BACVZ
Sequence: MLADKVKLSAKDILEKEFKTGVRGYRQEDVDKFLDMIIKDYETFHQEIEELQQENLQLKKQLEEASKKQPVQSNTTNFDILKRLSNLEKHVFGSKLYDE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: PURT_META3
Sequence: MLLGTPLFSNGTKILLLGSGELGKEVIIEAQRLGIECVAVDSYDNAPAMQVAHRSYVIDMKDGDALKAILEKEVPDYIIPEIEAINTDILIEMEEFGHQVVPTANAAKITMDREGIRRLASEQLNIPTAKYEFAESLEELKKAVKKIGAPCIVKPIMSSSGKGQSTVKSEKDEDIEYAWNYAQAGARGIGKKVIVEEFINFDYEITLLTARTAHGTVYCPPIGHIQDGGDYIESWQPHPMSEEMIKKAQEMANKITTVLGGNGIFGVELFIRGDEVIFSEVSPRPHDTGMVTMITQNMSEFEIHLRSILGLPVDIQLITAGASSVIKSKIHKYAPQYDISDAVKVPNTKLRIFGKPLAKVGRRMGVALASANTVEEARKNAKKCANGVIIR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.