PharMolix/UniProtQA huggingface dataset:
Protein: TAXB1_HUMAN
Sequence: MTSFQEVPLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSPVEELLTMEDEGNSDMLVVTTKAGLLELKIEKTMKEKEELLKLIAVLEKETAQLREQVGRMERELNHEKERCDQLQAEQKGLTEVTQSLKMENEEFKKRFSDATSKAHQLEEDIVSVTHKAIEKETELDSLKDKLKKAQHEREQLECQLKTEKDEKELYKVHLKNTEIENTKLMSEVQTLKNLDGNKESVITHFKEEIGRLQLCLAEKENLQRTFLLTTSSKEDTCFLKEQLRKAEEQVQATRQEVVFLAKELSDAVNVRDRTMADLHTARLENEKVKKQLADAVAELKLNAMKKDQDKTDTLEHELRREVEDLKLRLQMAADHYKEKFKECQRLQKQINKLSDQSANNNNVFTKKTGNQQKVNDASVNTDPATSASTVDVKPSPSAAEADFDIVTKGQVCEMTKEIADKTEKYNKCKQLLQDEKAKCNKYADELAKMELKWKEQVKIAENVKLELAEVQDNYKELKRSLENPAERKMEGQNSQSPQCFKTCSEQNGYVLTLSNAQPVLQYGNPYASQETRDGADGAFYPDEIQRPPVRVPSWGLEDNVVCSQPARNFSRPDGLEDSEDSKEDENVPTAPDPPSQHLRGHGTGFCFDSSFDVHKKCPLCELMFPPNYDQSKFEEHVESHWKVCPMCSEQFPPDYDQQVFERHVQTHFDQNVLNFD
What is the function of this protein?
Ubiquitin-binding adapter that participates in inflammatory, antiviral and innate immune processes as well as selective autophagy regulation (PubMed:30459273, PubMed:29940186, PubMed:30909570).  Plays a key role in the negative regulation of NF-kappa-B and IRF3 signalings by acting as an adapter for the ubiquitin-editing enzyme A20/TNFAIP3 to bind and inactivate its substrates (PubMed:17703191).  Disrupts the interactions between the E3 ubiquitin ligase TRAF3 and TBK1/IKBKE to attenuate 'Lys63'-linked polyubiquitination of TBK1 and thereby IFN-beta production (PubMed:21885437).  Recruits also A20/TNFAIP3 to ubiquitinated signaling proteins TRAF6 and RIPK1, leading to their deubiquitination and disruption of IL-1 and TNF-induced NF-kappa-B signaling pathways (PubMed:17703191).  Inhibits virus-induced apoptosis by inducing the 'Lys-48'-linked polyubiquitination and degradation of MAVS via recruitment of the E3 ligase ITCH, thereby attenuating MAVS-mediated apoptosis signaling (PubMed:27736772).  As a macroautophagy/autophagy receptor, facilitates the xenophagic clearance of pathogenic bacteria such as Salmonella typhimurium and Mycobacterium tuberculosis (PubMed:26451915).  Upon NBR1 recruitment to the SQSTM1-ubiquitin condensates, acts as the major recruiter of RB1CC1 to these ubiquitin condensates to promote their autophagic degradation (PubMed:33226137, PubMed:34471133).
What are the official names of this protein?
Tax1-binding protein 1, TRAF6-binding protein.
Protein: PSBU_GRIJA
Sequence: MAFISGPALPTARVNRTVAATPVRMASGEDTPVVSRRALLSSTLAAAAAALLSAAAPAKADREYGNVGFLGGGDKIDVNNANVRVYGRLPGMYPTLAGLIVANGPYKSVGDLYNIPGLDDKQTGLLKKYEDSFVALEPRPEYEIDKFNNGLYR
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, chloroplastic, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: FMT_SYNY3
Sequence: MMKTVFFGTPDFAVPTLEALLGHPDIDVLAVVSQPDRRRGRGSKLIPSPVKEVAVQAGIPVWQPERVKRCQETLAKLKNCQADFFVVVAYGQLLSPEILVMPRLGCVNVHGSLLPKYRGAAPLQWAIANGETETGVTTMLMDEGMDTGAMLLKTTTPIGLMDNLTAIGDRLARSGAELLVQTLKDLDAGQLQPIPQTETEATYAPLLKKGDFVINWHRSALEIHNQVRGFAPACHTAWGEQILKIISTVPLGAEFFPLLPEKYQDLATAYLNYSLEAGEPGNIIGTIKNWGPVLETGNGHLLLEQVQPPGKKPQSGWDFINGNRSTISFA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: PPSA_METJA
Sequence: MLIIQNTKGDSMKFIAWLDELSNKDVDIAGGKGASLGEMWNAGLPVPPAFVVTADAYRHFIKETGLMDKIREILSGLDVNDTDALTNASKKIRKLIEEAEMPEDLRLAIIEAYNKLCEMCGEDEVTVAVRSSATAEDLPEASFAGQQDTYLNIKGAENVVKYVQKCFSSLFTPRAIFYREQQGFDHFKVALAAVVQKLVNAEKAGVMFTVNPISENYDELVIEAAWGLGEGVVSGSVSPDTYIVNKKTLEIVDKHIARKETMFVKDEKGETKVVEVPDDMKEKQVLSDDEIKELAKIGLNIEKHYGKPMDVEWAYEKGKFYMLQARPITTLKKGKKEKKAKEEDIEAKILLKGIGASPGIATGVVKIIHDVSEIDKVKEGDILVTEMTTPDMVPAMKKAAAIVTDEGGLTCIEGDAKILTDRGFLKMKEVYKLVKNGEKLKVLGLNAETLKTEWKEIIDAQKREARRYEIGVYRKNKNTKDTIKITPDHKFPVFVNGELSKVQLCDIIDNNLSVLSIDYIPMIEEKYESLAEVMYLGGAVLSDGHIVRRNGKPIRVRFTQKDTEEKKDFIEKVKGDVKLIGGNFIEISNRNNVIEYQTSRKIPSEILGFIEVNINTIPLYATKDEIADLIAGFVDGDGCLSGKRRVEIYQNSSHIKKIEGLIVGLYRLGIIPRLRYKRSSTATIYFNNNLETILQRTRRIKLDKLKEFKKPVEDKKLIDISQILPELKEFDYKGYLYKTYKEKLFIGINKLEEYLSKIDKDGIERIKQKIKLLKESDIYSIRIKKVGEDYGEVYNITVKAENEFNHNYVVWTKHYTPIVVFNCHAAIVSRELGTPCVVGTKKATKVLKDGMIVTVDGEKGIVYEGEIKKVEEKEKKQEVVVQQAPIITATEVKVNVSMPEVAERAAATGADGVGLLRAEHMILGLGKHPRKILEEEGEEALIEALMEGIRKVADAFYPRPVTYRTLDAPTDEFRGLEGGENEPIEHNPMLGWRGIRRDLDEVDILKCELKAIKRLREEGYKNIEIMIPLVTHPDEVRRVKEIMREVGLEPCKDIPFGIMVETPAAALIIEDFIKEGINFVSLGTNDLTQYTIAIDRNNELVSKYYKEDHPAVLKLVEHVIKTCKKHGIKTSICGQAGSRPHIVEKLVEWGIDSVSANIDAVETIRRVVARTEQKVILNYIRKSYVERE
What is the function of this protein?
Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
What are the official names of this protein?
Probable phosphoenolpyruvate synthase, PEP synthase, Pyruvate, water dikinase.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: MLTF_SALTY
Sequence: MKKLKINYLFIGILTLLLAAALWPSIPWFGKTENHIAAIQARGVLRVSTIDSPLTYSVINGKKYGLDYELAQQFANYLGVKLKVTVRQNISQLFDDLDNGNADLLAAGLVYDSARVKNYQPGPMYYSVSQQLVYRVGQYRPRSLATVNENQLTIAPGHVVVNDLQRLKETKFPDLSWKVDDKKGSTTLLEEVISGKLDYTIADSVAISLFQRVHPELAVALDVTDEQPVTWFSRLDDDNTLSAALLDFFNSINEDGSLARIEEKYLGHGDDFDYVDTRSFLRAVDNVLPELEPLFKKYAKEIDWRLLAAISYQESHWDPLATSPTGVRGLMMLTKNTAQSLGLTDRTDAEQSISGGARYLEDMMAKVPETVPEDERIWFALAAYNMGYAHMLDARSLTVKTKGNPDSWTDVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQEAEAMKLAQDYPAVSPEELNKAPFPFLSFLSQSSGYLTHSPSLLFTPQKKEEK
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: CYB_MARME
Sequence: MTNIRKTHPLAKIINNSFIDLPAPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYMYPETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIVSALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALFLILVLMMLVLFSPDLLGDPDNYIPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILVLAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFITIGQLASILYFAILLILMPTISIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FIBA_APOPA
Sequence: MFSFIMKAAILLILVGCISFCISSEPLNESEITFEREERSLADPAGRQKRQSGLSCPKRISHSPEYPRDCYDILQSCSGQSPPSGQYYIQPDGGNLIKVYCDMETDEGGWTVFQRRIDGTINFYRSWSYYQTGFGNLNTEFWLGNDNIHYLTSQGDYELRVELNNTLGNHYYAKYNKFRIGDSFSEYLLVLGAYSGTAGDSLAYHNTMRFSTYDNDNDVYSINCASHSSYGRGAWWYKSCLLSNLNGQYYDYSGAPSIYWSYLPGDNDQIPFAEMKLRNRSI
What are the official names of this protein?
Fibrinogen-like protein A, FREP-A.
Protein: RL30_PSEA7
Sequence: MATVKVTLVKSLNGRLANHKACVKGLGLRRINHTVEVQDTPENRGMINKAYYLLRVEG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: YRDA_SHIFL
Sequence: MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVVIRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGNRVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAGLRYSANNYVKWKDEYLDQGNQTQP
What are the official names of this protein?
Protein YrdA.
What is the protein family that this protein belongs to?
Belongs to the gamma-class carbonic anhydrase family.
Protein: NUB1_MOUSE
Sequence: MAQKKYLQAKLTQFLREDRIQLWKPPYTKENKEVGLAVKDLAKKYSERLECCENEVENIIEEIRRKAIERGTGNEHYRTTGIATIEVFLPPRLRKHDKKSLLETRLHVTGRDLRCQIAETFGFQENYIKIVINKKQLQLGKSLEEQGVTHNVKAMVLELKQSEEDVRKNLQLEEEEQNEAELKERRIQRTKRGLEILAERAEMVVDPETMPYLDIANQTGRSLRIPPAERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADRYFCECKELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIQNYHSGNGEEAREYLNKARQLFKELYIDPSKVHNLLQLGFTAQEARLGLRACDGNVDHAATHISNRREELAQIRKEEKEKRRRRLENVNTLRGMGYSTQAAKQALHQARGNLDDALKVLLSNPHMWWLQDADPENNSRQASPSQESINQLVYMGFDTVVAEAALRVFGGNVQLAAQTLAHHGGSLPPDLQFSGEDSSPTPSTSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEVIIAEYLSYVESISSAAKNN
What is the function of this protein?
Specific down-regulator of the NEDD8 conjugation system.  Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation (By similarity).
What are the official names of this protein?
NEDD8 ultimate buster 1, Negative regulator of ubiquitin-like proteins 1, Protein BS4.
What are the subcellular locations of this protein?
Nucleus. Note=Predominantly nuclear.
Protein: PTH_CAMLR
Sequence: MTLVVGLGNIGEQYAQTRHNVGFMLIDLLLKDLEVAKLSNTKFKGELFKSSLAFFLKPSTYMNLSGESVKAVSDFYKCDRIIVIHDDIDLNLGTLKFKIGGSSGGHNGLKSIDNLCGNAYERVRIGVGKDQDVISHVLGKFKQEEQESLNKVLEQAKKALFELLKSNIEQVASKYSIRN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHBL2_MOUSE
Sequence: MAVAHEMEMESVNLNMEREGKEEPEEEKMKGNGEGKDFPRSRKVHRIVSKWMLPEPVRRTYLERANCLPPPLFIILISLAELAVFIYYAVWKPQKQWITLDTGILESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPAFGIVRLLVIILIVASDMGFALYRRFFVPANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIFLSPAN
What is the function of this protein?
Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.  Known substrate: EFNB3 (By similarity).
What are the official names of this protein?
Rhomboid-related protein 2, RRP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
[Rhomboid-related protein 2, C-terminal fragment]: Cell membrane; Multi-pass membrane protein.
Protein: MZM1_KLULA
Sequence: MSQALGAYRNGLRAARVAFKGDLRMLMAARQQMRESMVNPPNPELPPDQQIKLMNDVAQFLRQNVVQGKRTKDDKYHLNIHKDTELGDNETIKTTKKTLAAQGGGCCGGGAGLYK
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: AL3A2_RAT
Sequence: MERQVQRLRQTFRSGRSRPLRFRLQQLEALRRMVQEREKDILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAKKNLLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTLQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQYLDQDLYMIVNGGVEETTELLRQRFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDRDCDLDVACRRITWGKYMNCGQTCIAPDYILCEASSQDQIVQKIKDTVKDFYGENVKASPDYERIINLRHFKRIKSLLEGQKIAFGGETDEATRYIAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVEEAINFINDREKPLALYIFSHNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLKGESVNKLRYPPNSESKVSWSKFFLLKQFNKGRLQLLLLVCLVAVAAVIVKDQL
What is the function of this protein?
Catalyzes the oxidation of medium and long-chain aliphatic aldehydes to fatty acids.  Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length.  Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid (By similarity).
What are the official names of this protein?
Aldehyde dehydrogenase family 3 member A2, Aldehyde dehydrogenase 4, Fatty aldehyde dehydrogenase, Microsomal aldehyde dehydrogenase, msALDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Microsome membrane. Endoplasmic reticulum membrane; Single- pass membrane protein; Cytoplasmic side.
Protein: CYSJ_BAUCH
Sequence: MTQQNAPKDLPPLSAEQLDRLQAISSDLSNLQLAWASGYLWNKASHSIPIDYTASQQVITVLSASQTGNARRLAVQLYEDLLAAQLSVVIINAGDYKFKQIAQEKWLLIVTSTQGDGDPPEEAIALYKYLFSKKAPVLNNIQFAIFGLGDSSYTYFAKIGKDFDSRLAELGAQRLYDRVDADVDYQEKADIWRREIVKILQTKLVTVNAKQQLSVINNRIEVKNNLYTKEEPFTAHLVVKQKITSRSSKKDIRHLEIDIAGSGLNYQPGDALGVWYENDPVLISEILELLGLTGNELVQVKEKNIPLNEALQKHYELTNNTAEIVKSYAYITRNSSLLALVDDQQQLKQFAFSTPFIDMIQRIPVELHPKQLLTLLRPLMPRLYSIASSQAEVGDEVHLTVSVVRYEIDGKIRTGGASSYLAYRLQESEPIRVFIEHNDNFRLPNNPNTAIIMIGSGTGIAPFRGFMQQREATTAKGKNWLFFGNQHLTDDFLYQVEWQRYIKNGLLNKIDVAWSQDQNKKIYVQDRLLEKGIELWNWIQDGAHIYVCGNANLMARDVEKALVKLIAIHGRMDYEQADEFLSELRIARRFQRDTY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: RPOB_NICTO
Sequence: MLGDGNEGISTIPGFNQIQFEGFCRFIDQGLTEELYKFPKIEDTDQEIEFQLFVETYQLVEPLIKERDAVYESLTYSSELYVSAGLIWKNSRDMQEQTFFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTGTIISDWGGRSELEIDRKARIWARVSRKQKISILVLSSAMGLNLREILENVCYPEIFLSFLSDKERKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNRRLNLDIPQNNTFLLPRDILAAADHLIGLKFGMGALDDMNHLKNKRIRSVADLLQDQFGLALVRLENVVRGTICGAIRHKLIPTPQNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHAKIGHWGSLESPFYEISERSTGVRMLYLSPGRDEYYMVAAGNSLALNRDIQEEQVVPARYRQEFLTIAWEQVHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGALAIAEREGRVVYTNTDKILLAGNGDILSIPLVIYQRSNKNTCMHQKLQVPRGKCIKKGQILADGAATVGGELALGKNVLVAYMPWEGYNSEDAVLISERLVYEDIYTSFHIRKYEIQTHVTSQGPEKVTNEIPHLEAHLLRNLDKNGIVMLGSWVETGDILVGKLTPQVVKESSYAPEDRLLRAILGIQVSTSKETCLKLLIGGRGRVIDVRWIQKRGGSSYNPETIRVYILQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRSVDMVFNPLGVPSRMNVGQIFECSLGLAGSLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGNPFEQPVIIGKPYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPNPEDAPESFRLLVRELRSLALELNHFLVSEKNFQINRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SRRT_DROSE
Sequence: MADSDDEYDRKRRDKFRGERDSYRTERRDDRRPVGGSAGARDEWAERNPFRGAASAGGGGARHRPDYSDYRGPGARPRYGSPGRDLPPAKRMRPDWGDGDVRANPRFGGYDPYLMQAWNDHYQSMHSAYSHAGHAPPVRESIGGGGSDTLTQPAMLNLKQFLDTQDENISDSEVMRKYTDYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRNEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEPMQSVKEVEKTINSPKDEISEADPLPAVVSTQRKPVGPVNSDEENWDDDNDAENSTPKKELAEDSKDSDSKPEEKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRTEQKIEAEKDRQEATKAKQEPQSPKLDEVEGNDTTEPKGLDSKINTVEIDDTLKSPEISSNPIKNTDNGDSSKVEEDEEKPSVGKDKVVETETIDLDKVKDCQPRALHRTSSIFLRNLAPSITRSEIEAMCNRFTGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEVPKDDPNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLGLTGENKDTEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPVRVTNNDVQEYIKMYETKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYRPPMYPPFSAMPYGFGPPMMGGGRGGRNFPPARRELPLEHQRRLIGYHDLDAPANSDMFD
What is the function of this protein?
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi).  Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
What are the official names of this protein?
Serrate RNA effector molecule homolog, Arsenite-resistance protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the ARS2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1527_STAES
Sequence: MHTILLVVFMIILGAIIGGVTNMIAIKMLFHPFKPYYIFRFRIPFTPGLIPKRREEIARKIGQVIEEHLITEELIRQKLNQPQSRNMIQQLIHKQISKLKNDDVTIKKIAGFLGIDVNELVDYKLTTKFLNKLNFWYESNKYRKLSEILPQSFLDQCKGQIEYITDFLCERARNYLSSEKGERDIYEMLDTFFNEKGRIIGLLQMFMTKESIADRIQHELIRLTQHPQSQKIITKVLNDEYEIFKDKNLDEIIKEQQFKNYSQLVLNELKTYLNLKDKTERPIKQVVPQFIQFLEDDTSKRMTDFIIKGTSKHLTNIMKKINLRQLVEEQINTFDLKYIENLIIDIANKELKLIMTLGFILGGIIGFFQGVIAIFV
What are the official names of this protein?
UPF0754 membrane protein SE_1527.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL6_ALKMQ
Sequence: MSRIGLKPIEVPQGVEITVDEKNIVTVKGPNGQLSEKIHRDITVETEANVINVVRPTENKKHKSLHGLSRTLVANMVEGVTKGYEKKLELVGVGYRATMQGKKLVLSLGFSHPVEIDQPEGLTIEVPSQTQVTVKGIDKQQVGNFAAKIREYRKPEPYKGKGVRYAGEVVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: UREG_STAAC
Sequence: MANPIKIGIGGPVGAGKTQLIEKVVKRLSKEMSIGVITNDIYTKEDEKILVNSGVLPESRIIGVETGGCPHTAIREDASMNFAAIDELLERHDDIELIFIESGGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASLEQMAEDTKVFRGKRPFTFTNLKTDEGLDEVIDWIERDTLLKGLS
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 117L_IIV3
Sequence: MEKQFNVWSVQNDIVCQRQLTINLRRVRNEYDNAVASVAAPSCPPSIPAQTRTCGRKLKLDWFKCTIL
What are the official names of this protein?
Uncharacterized protein 117L.
Protein: GLND_ACIBT
Sequence: MINTSPLLNYVSSHHDIKAINQWRTDVEKQLQDSYENGQSIREIIKARSDLVDEALVFLWKHAELDQSKLGLFAVGGYGRREMLPYSDVDIMILSEDEISEENEKRISTFISSLWDVGNFKPGISVRTIQSCVEQAATDLTVATTLIEARLITGNTQLAKWPRRIVSQTWTDKTFYDAKMAEQAKRYHQHNNTESNLEPDIKNAPGGIRDINQIGWIAKRHFRVNRIYDLVHLGFISEFELAVLEEAESFLWEIRHHLHRLAKRDENRLLFDHQREIAAKFGYVRQEGQPVNYGVEQFMKRYYRTAQQVSTLNEMLLAYFSESVITPRLPNYERKIEVVNDHFKIVDNKLAVQHHKIFAEHPSAILELFYILANRPDIEGIRARTLRLLILAAKRINQSYRDNPEHQALFMSIIRSPYRLYDTLVAMKRYGVLGNYIPAFGQIMGLMQYDLFHIYTVDAHTLLLLRNLNRFREPEFAKEFPVVSSVFQRLARQDIVFIAALFHDIAKGRGGDHSELGAEDAIEFGRAHGFTERECKLIAWLIQNHLLMSLTAQKKDISDPDVVKDFAEKLGDMEHLDYLYTLTVADINATNPKLWNTWRASLMRQLYTHARDVIRTGLGRPVDYQMLIEDTKFAASELLVNNFALADVEKVWQELGDEYFIKESADEIAWHTQAILKHGDNPEPLVLLRAHRKAAQDAVQIFIYTRDQPNLFATTVAVLDRMNLDVQDAKIITASTAFSLDTYVVLDRFGTLLTDPEREETVKNALVKALSQPDQYPGLMQRRIPRQLRHFDIENTVDVTLNEALQQNMVEISTLDHPGLLARVGGLFMMQGLDIHSARIATLGERAEDIFFVTKKDGKPLNHEEVKLFSEKLKAALDEASNQICQH
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: HIMG_ASPJA
Sequence: MAPALTQSLNGATPQVKAALHHLDANTVSIDDIIHYLKHHGGVVVQNLISEEILQEVGADIKPYFDALVEPGFFSSKTRIVTRLPNKSIAFVEKIFGNQVFQDICDHFLTSHHRGWYGNEQYTYSPHPVFNSALAFSTLPGNETQSLHRECMGQHNKLPAIAPEDYPIGRDTVLGMFVADTRTTRENGATRFIPGSHLQSTLDPPDESQTVPVEMNRGDVFLMLGSCYHGASANVSQAEERILYSTFMTQSTRRQLTTCLFLVQEENIYLSVPVDRVRVFSPRMQKRLGFSASDPLFGWVDVKDPRKVFNLPGLSEGQHIDV
What is the function of this protein?
Polyketide synthase-nonribosomal peptide synthetase; part of the him gene cluster that mediates the biosynthesis of himeic acid A, a ubiquitin-activating enzyme (E1) inhibitor (PubMed:29314577).  First, himA, together with the trans-enoyl reductase himH, catalyzes the formation of apolyketide chain, which is then condensed with leucine by the NRPS activity of himA.  Dieckmann cyclization and release from himA gives a tetramic acid intermediate as the product of himA PKS-NRPS (PubMed:29314577).  HimG then catalyzes alpha-oxidation of the tetramic acid ring, with a subsequent rearrangement to yield apyrone intermediate (Probable).  Two terminal methyl groups of polyketide and amide side chains are oxidized to carboxylic acids by himC cytochrome P450 monooxygenase to form himeic acid A (Probable).  Himeic acid A is further converted to himeic acid B and C during culture growth.  No gene responsible for pyrone to pyridone conversion was found in the him gene cluster and himeic acid A is non-enzymatically converted to himeic acid C by the incorporation of an ammonium nitrogen atom in a pH5 buffer, and to himeic acid B at a conversion ratio of 50% during incubation in MeOH for 5 days (PubMed:29486950).
What are the official names of this protein?
Dioxygenase himG, Himeic acid A biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.