PharMolix/UniProtQA huggingface dataset:
Protein: IF2_LACGA
Sequence: MMAKKRIYEVAKELGIENKIVVKKAQDLGFDVKSHMSSLDDKQVSKLVDSFKSANTTKPSTEKDSKNSSRKEKTKIKVSVGAIRRRDNKNDHDNRHGNNKRRNNKFKKQQNDRRAERNKPQTEAKSAARDLLNKFKKKQRAEASELNAQTEASRRKWHQEQNPQRSKVKKVENTRKPKEEKLEGAAAVKARVQASQKPVGPKIIKPSPARNKAKRPTVKKVEPIAPVVPAPQKEETKPTRKKDFTRKKREVPDYERERSEHSDKARRRRNKKNKRINQSKEIKKQPTQRKERPLPETLVYEEGMNAQDLGKLLHREPAEIVKKLFMLGVMTNQNQSLDKDTIELLAAEYGIEAQEKVHEDISDIDTLYTKEMEESKASKHQEKRPPVVTIMGHVDHGKTTLLDRLRHTNVSEHEAGGITQKIGAYQVRIDDRLITFLDTPGHAAFSNMRARGAEITDIVVLVVAADDGVMPQTIEAIDHAKSAGVPIIVAVNKIDKPGANPDHVMEQLMKYGLVPEDWGGDTIFVKISAKTGKNVEELLQMILLQADVMELKADPDQKAIGTVIEARLDKGRGSVADVLVQQGTLKVGDPIVVGDTFGRVRVMTNDKGRRVKKATPSAPVEITGLNDVPEAADKLVVFEDEKTARSVGEQRAKNALEKQRENVQHVTLDNLFDTMKKENMKEVDIVLKADVQGSAEALQQSLEKIEVEGVRVNIIHSGVGAINESDVTLAGASNAFIVGFNVRPTNTAKSQADAEGVDIRLYNIIYKVMDDVEAAMKGMLEPTYEEKVTGNLTVRETWKVSKIGTIAGAFVDNGYVTRDSGIRVIRDGIVKYDGKVASLKRFKDDVKEVKQGFDCGITIENFNDIKVDDQLEAYEMQEVPVK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_PSEPW
Sequence: MRILISNDDGVTAPGLAALHGALVDYAECVVIAPDQDKSGAGSSLTLDRPLHPQTLANGFISLNGTPTDCVHLGLNGLLPETPDMVVSGINLGANLGDDVIYSGTVAAALEGRFLGGTSLAFSLLSRLPDNLPSAAFIARRLVEAQSRLELPPRTVLNVNIPNLPLEHIRGIQVTRLGHRARAAAPTKVVNPRGKEGYWIAVAGDAEDGGPGTDFHAVMQGYVSITPLQLDRTFNDAFEQLHGWLEGVL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_LARHH
Sequence: MLQPTRLKYRKVHKGRNTGIATRGTKVSFGDFGLKAVGRGRLTARQIEAARRAMTRHIKRGGRIWIRVFPDKPITKKPAEVRMGNGKGSVEYWVAEIQPGKMLYEMEGVSEELAREAFRLAAAKLPIATTFVVRQVGQ
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: GR77A_DROME
Sequence: MPLPLGDPLALAVSPQLGYIRITAMPRWLQLPGMSALGILYSLTRVFGLMATANWSPRGIKRVRQSLYLRIHGCVMLIFVGCFSPFAFWCIFQRMAFLRQNRILLMIGFNRYVLLLVCAFMTLWIHCFKQAEIIGCLNRLLKCRRRLRRLMHTRKLKDSMDCLATKGHLLEVVVLLSSYLLSMAQPIQILKDDPEVRRNFMYACSLVFVSVCQAILQLSLGMYTMAILFLGHLVRHSNLLLAKILADAEHIFESSQKAGFWPNRQELYKGQQKWLALELWRLLHVHHQLLKLHRSICSLCAVQAVCFLGFVPLECTIHLFFTYFMKYSKFILRKYGRSFPLNYFAIAFLVGLFTNLLLVILPTYYSERRFNCTREIIKGGGLAFPSRITVKQLRHTMHFYGLYLKNVEHVFAVSACGLFKLNNAILFCIVGAILEYLMILIQFDKVLNK
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 77a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr77a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: F168A_MOUSE
Sequence: MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW
What is the function of this protein?
In cancer context, protects cells from induced-DNA damage and apoptosis.  Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation.  Decreases POLB ubiquitation and stabilizes its protein levels.
What are the official names of this protein?
Protein FAM168A.
What is the protein family that this protein belongs to?
Belongs to the FAM168 family.
Protein: ATPD_SHEB5
Sequence: MAELTTIARPYAKAAFDFAIEQDAVDSWAEMLTFAALVSENETMQPLLAGSLASTKLAALFISVCGEQVNVQGQNLIKVMAENGRLKVLPAVSQLFTEYRNEWAKEVEADVVSATELSSEQQQQISISLEKRLARKVKLNCSTDAALIAGVIIKTGDLVIDGSVRGKLSRLSDKLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HXK3_ARATH
Sequence: MGKVAVAFAAVAVVAACSVAAVMVGRRMKSRRKWRTVVEILKELEDDCDTPVGRLRQVVDAMAVEMHAGLASEGGSKLKMLLTFVDDLPTGREKGTYYALHLGGTYFRILRVLLGDQRSYLDVQDVERHPIPSHLMNSTSEVLFNFLAFSLERFIEKEENGSDSQGVRRELAFTFSFPVKHTSISSGVLIKWTKGFEISEMVGQDIAECLQGALNRRGLDMHVAALVNDTVGALSLGYYHDPDTVVAVVFGTGSNACYLERTDAIIKCQGLLTTSGSMVVNMEWGNFWSSHLPRTSYDIDLDAESSNANDMGFEKMISGMYLGDIVRRVILRMSEDSDIFGPISPVLSEPYVLRTNSVSAIHEDDTPELQEVARILKDIGVSDVPLKVRKLVVKICDVVTRRAGRLAAAGIAGILKKIGRDGSGGITSGRSRSEIQMQKRTVVAVEGGLYMNYTMFREYMEEALVEILGEEVSQYVVVKAMEDGSSIGSALLVASLQS
What is the function of this protein?
Fructose and glucose phosphorylating enzyme (By similarity).  May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity).  Plays a role in plant growth and development, perhaps by mediating cross-talk between glucose and hormone response pathways (PubMed:19706780).  Involved in root hair cell development by mediating certain aspects of cross talk between glucose and ethylene response pathways (PubMed:22366209).
What are the official names of this protein?
Hexokinase-3, Hexokinase-like 1.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: DNAG_MYCPU
Sequence: MNNLWEIEKKILEKTTLSNLIGKLISIKPKGKSFWALCPFHDDKNASLSISDQKAMFSCFSCNVRGGLFVFYSKFLNKSYVEVANMLAKEFDLDFHFDQQEKEKYNENEQLFIDVTSIANHYFKVSLKSQVHSNSKLVDFLKSRGISRETASEFEIGYDDGNFWKIPNKEKKNFSFFLSNNLIVKKETNQYYDFFYKRVVFPIHNSFGDVVGFSGRALDENNIKYLNSPESLVFKKHKILYNWAKAKEKAIQEKKLYITEGFMDTIALYKIGIKNAIAIMGTNLSNEQLELIPKDIELIFFLDGDQAGKNAVYNILKKIIKMRSKISVIENDSKQDPDELLKQKGANFLKELIEKNKKPAIDYLYEFLLTSKYNINNSEHLISFVNDFAPLLSSQNNIVIDKYENLLMKHSINIRKFLTYQNQKYDRINQYNSLQQRFYEEPKQKKKANSREEILKKQYQNLYVKLLLSLLNSNALLEYFLRHNIEERIIFEQTNNGQESKLKDILRKIIKIQKEKKSETTIEDLPLEDQEILRWYLQKDSWFKSDYAKEGDLDLLANQISESYLEYEKSQKISKTLEMPSLDEEKQKILKRVILQRRSKND
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: NADA_GEOTN
Sequence: MNVLEQFKQLDNMPEQYKTMDRDELEARARAVKEQLGRRLFIPGHHYQKDEVIQFADATGDSLQLAQLAAKNNEAEYIVFCGVHFMAETADILTSEEQTVILPDLRAGCSMADMADVFQVERAWAALTDRFGETILPLVYVNSTAAIKAFVGRNGGATVTSSNAQKMVAWAFSQKERIFFLPDQHLGRNTAYALGVGLDEMAVWDPYEETLQGNGDFDKVKVILWKGHCSVHENFNVRQIEHIRQTKPETKVIVHPECSWDVVQQADYAGSTKYIIETIRNASPGSRWAIGTEMNLVNRLMHEHPDKEIISLNPYMCPCLTMNRIDLPHFVWALESLSEGTVVNRITVPKEVAFEAKLALERMLALA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_CLOD6
Sequence: MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQAVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDRKIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDTLIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMKARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWVKVKENWRNLQNYINNFGYNDK
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: ACNA_STAEQ
Sequence: MASNIKEQAKKQFELNGQSYTYYDLQTLEEKGLAKISKLPYSIRVLLESVLRQEDDFVITDDHIKALSKFGNAGNEGEVPFKPSRVILQDFTGVPAVVDLASLRKAMNDVGGDINKINPEVPVDLVIDHSVQVDSYANPEALERNMKLEFERNYERYQFLNWATKAFDNYNAVPPATGIVHQVNLEYLANVVHVRDVDGEKTAFPDTLVGTDSHTTMINGIGVLGWGVGGIEAEAGMLGQPSYFPIPEVIGVRLTHSLPQGSTATDLALRVTEELRKKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDEESLKYMKLTGRDEEHIELVKEYLQQNHMFFDVEKEDPEYTDVIDLDLSTVEASLSGPKRPQDLIFLSDMKKEFEKSVTAPAGNQGHGLDQSEFDKKAEINFNDGSKATMKTGDIAIAAITSCTNTSNPYVMLGAGLVAKKAVEKGLKVPEFVKTSLAPGSKVVTGYLRDSGLQQYLDDLGFNLVGYGCTTCIGNSGPLLPEIEKAVADEDLLVTSVLSGNRNFEGRIHPLVKANYLASPQLVVAYALAGTVDIDLQNEPIGKGKDGKDVYLQDIWPSIQEVSDTVDKVVTPELFLEEYKNVYHNNEMWNEIDVTDEPLYDFDPNSTYIQNPTFFQGLSKEPGKIEPLKSLRVMGKFGDSVTTDHISPAGAIGKDTPAGKYLLDHDVAIRNFNSYGSRRGNHEVMVRGTFANIRIKNQLAPGTEGGFTTYWPTGEIMPIYDAAMKYKEDGTGLVVLAGNDYGMGSSRDWAAKGTNLLGVKTVIAQSYERIHRSNLVMMGVLPLQFQQGESAEALGLDGKEEISVDINEDVQPHDFVNVTAKKENGEIINFKAIVRFDSLVELDYYRHGGILQMVLRNKLAQ
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate.  The apo form of AcnA functions as a RNA-binding regulatory protein.
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, Iron-responsive protein-like, IRP-like, Probable 2-methyl-cis-aconitate hydratase, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: IL2RA_PIG
Sequence: MEPSLLMWGFFTFTMIPGCMAGACVQQPPSLRNATFKILGYKVGTTLNCDCQRGFRRDPSSGPYMICRGNSSHSFWENKCQCMPTSSPRIPVKQVTPRPEEQKERKTTETQGQMQPPNQANLPGHCKEPPPWEHESLKRVYHFMEGQTVRYQCLPGFRDGSAQNNSAQSVCKKQEDQEVMRWTQPKLKCKSEKENGSFPEPQMSTAAPPTTKTSLPTRTKGTTDSQNLTEVPATMQPIIFTTQYQLAVAGCVLLLLSILLLSGLTWQRRR
What is the function of this protein?
Receptor for interleukin-2.  The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.  TREGs suppress the activation and expansion of autoreactive T-cells.
What are the official names of this protein?
Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CVC1_HHV2H
Sequence: MNAHFANEVQYDLTRDPSSPASLIHVIISSECLAAAGVPLSALVRGRPDGGAAANFRVETQTRAHATGDCTPWRSAFAAYVPADAVGAILAPVIPAHPDLLPRVPSAGGLFVSLPVACDAQGVYDPYTVAALRLAWGPWATCARVLLFSYDELVPPNTRYAADGARLMRLCRHFCRYVARLGAAAPAAATEAAAHLSLGMGESGTPTPQASSVSGGAGPAVVGTPDPPISPEEQLTAPGGDTATAEDVSITQENEEILALVQRAVQDVTRRHPVRARPKHAASGVASGLRQGALVHQAVSGGALGASDAEAVLAGLEPPGGGRFASRGGPRAAGEDVLNDVLTLVPGTAKPRSLVEWLDRGWEALAGGDRPDWLWSRRSISVVLRHHYGTKQRFVVVSYENSVAWGGRRARPPRLSSELATALTEACAAERVVRPHQLSPAAQTALLRRFPALEGPLRHPRPVLQPFDIAAEVAFVARIQIACLRALGHSIRAALQGGPRIFQRLRYDFGPHQSEWLGEVTRRFPVLLENLMRALEGTAPDAFFHTAYALAVLAHLGGQGGRGRRRRLVPLSDDIPARFADSDAHYAFDYYSTSGDTLRLTNRPIAVVIDGDVNGREQSKCRFMEGSPSTAPHRVCEQYLPGESYAYLCLGFNRRLCGLVVFPGGFAFTINTAAYLSLADPVARAVGLRFCRGAATGPGLVR
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.
What are the official names of this protein?
Capsid vertex component 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: SOJ_THET2
Sequence: MLRAKVRRIALANQKGGVGKTTTAINLAAYLARLGKRVLLVDLDPQGNATSGLGVRAERGVYHLLQGEPLEGLVHPVDGFHLLPATPDLVGATVELAGAPTALREALRDEGYDLVLLDAPPSLSPLTLNALAAAEGVVVPVQAEYYALEGVAGLLATLEEVRAGLNPRLRLLGILVTMYDGRTLLAQQVEAQLRAHFGEKVFWTVIPRNVRLAEAPSFGKTIAQHAPTSPGAHAYRRLAEEVMARVQEA
What is the function of this protein?
ATPase probably involved in chromosome partitioning.  Cooperatively binds dsDNA, forming nucleoprotein filaments in a strictly ATP-dependent fashion.  Can also bind ssDNA with lower affinity.
What are the official names of this protein?
Chromosome-partitioning ATPase Soj.
What is the protein family that this protein belongs to?
Belongs to the ParA family.
Protein: KCY_STAAN
Sequence: MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQIK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_XANOR
Sequence: MTQTNGFDALHAHAQRLRGAAIPALLAAEPERPTQYAWQVGPLYFNFARQKYDRAALDALFAIARERDLAGAFQRLFRGEQVNVTEQRAALHTALRGDLTDAPVASEAYATAAEVRQRMGALIQQLEATDVTDIVSVGIGGSDLGPRLVADALRPVSGARLRVHFVSNVDGAAMQRTLATLDPARTAGILISKTFGTQETLLNGSILHAWLGGSERLYAVSANPERAAKAFDIAPGRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLEGAAQFDAHALNTPLEENVAVLHGLTAVWNRNLLGSATHAVMTYDQRLALLPAYLQQLVMESLGKRVKLDGSAVDSDTVSVWWGGAGTDVQHSFFQALHQGTSVVPADFIGTVHNDDPYAENHVALMANVLAQTEALANGQDSSDPHRSYPGGRPSTVILLDALTPQALGALISMYEHSVYVQSVMWGINAFDQFGVELGKQLASQLLPALKGESADVADPVTRELLSKLRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIG4_ARATH
Sequence: MSTSQTLGGATRCGRIIGPSLDKIIKNAAWRKHTYLVSSCKSVLDKLESLPDDFHDPSSVVSGLAASDADSVLQPFLLSLETAYSKVVEPSLDCAFKLFSLSILRGEIQSSKQDSILFKLVNAVSKVGAIAEEPIQLAVLRVLLAAVRSPCILIRGDCLLHVVKTCYNIYLGGLSGTTQICAKSVLAQMMLVIFTRSEEDSLDVSVKTIYVNELLTFTDKSVNEGSSVYFCQGFVNEVMAAGQGSPLPPPDVIQILLQNPETETVMTPDSPSFRGYVANGEGDSETGDMSKVRQDAFLLFKNLCKLSMRFSSKENNDDQIMVRGKTLSLELLKVIIDNGGSVWRTNESFINAVKQYLCLSLLKNSAVSIMSIFQLQCAIFMSLLSKLRSVLKAEIGIFFPMIVLRVLENVLQPSYLQKMTVLNLLDKMSQDPQLMVDIFVNYDCDVESSNILERIVNGLLKTALGPPTGSSTTLSPAQDSTFRNDSVKCLVNLAKAMGNWMDQQLKVNETVWPKGSQVYASMDSNASQISELEGTISDCDSQPDTSNPEAYDASMLEQRRAYKIELQKGISLFNRKPSKGVEFLISTKKIGSSPEEVASFLMKTAGLNGTVIGDYLGERDELPLKVMHAYVDSFNFEKKDFVEAIRFFLRGFRLPGEAQKIDRIMEKFAEHYWKCNPGSFTSADTAYVLAYSVIMLNTDAHNNMVKDKMTKADFVRNNRGIDDGKDLPEEYLGSLYDRVVKEEIRMNSDTLAPQNKQVNGLNKLLGLDGILNLVSWMQPDEKPHGANGRLIRDIQEQFQAKPEKSESVYHTVTDISILRFILEVSWGPMLAAFSVTIDQSDDRLATSLCLQGFRYAVHVTAVMGMQTQRDAFVTSMAKFTNLHCAADMKQKNVDAVKAIITIAIEDGNHLHGSWEHILTCLSRIEHLQLLGEVSPSEKRYVPTKKAEVDDKKALGFPNLKKRGSFQNPSVMAVVRGGSYDSTSLVKSVPKLVTPEQIKSFIANLNLLDQIGNFELNHVYANSQRLNSEAIVSFVKALCKVSMSELQSPTDPRVFSLTKLVETAHYNMNRIRLVWSRIWNVLSDFFVSVGLSENLSVAIFVMDSLRQLSMKFLEREELANYHFQHEFLRPFVVVMQKSSSAEIRELIVRCVSQMVLSRVSNVKSGWKNVFTVFTTAALDERKNIVLLAFETIEKIVRDHFHCIIETEITVYADCIRCLITFTNSKFEGDIGFNTIEFLRFCALKLEEGGLVLNEKLKNNTISALKEDFSDTQSFTDLDEQVSYWIPLLTGLCKQVSDPRPAIRKRSIEVLFHILMDHGHLFTRPFWTGIFSSIILPVFNNIRSKTDMLFEESVDSPSSASLDTEETTWDVETSTLALQLLVDLLVKFFRSVRSQLPSVVSIIVGFIKSPFQGSTGSGISVLLHLADGLARSASEDEWREIFLALKEAASLTFAGFMKVLRTMDDIEDVETLSGQSVNIGDLDDDSLHIMSYVVSRTKKHIDVLSQIVEVVSDLYRRNQFSLSASHVDILADIFSCIASHAQQLNTDTVLRRKFKRACSVQNLTEPQLLNFENEAYKSYMMFLQDMVTCNPNVSKELDLESRLVTECAKIVKIYLKCTDPQQQEQQQRKPVLWVLPMESDRVEEATARTSLLVSSLEALCSLEAESLKKHVSSFFPLLVDLVRTEHCSPQVPYVLSNVLKSCIGPILA
What is the function of this protein?
Activates the ARF proteins by exchanging bound GDP for free GTP.  Plays a role in vesicular protein sorting (By similarity).
What are the official names of this protein?
Brefeldin A-inhibited guanine nucleotide-exchange protein 4, BIG4, ARF guanine-nucleotide exchange factor BIG4.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side. Note=Soluble and partially membrane-bound.
Protein: TNAA_VIBC3
Sequence: MENFKHLPEPFRIRVIEPVKRTTREYREKAILNAGMNPFLLDSEDVFIDLLTDSGTGAITQEMQAAMFRGDEAYSGSRSYHALARAVKDIFGYEYTIPTHQGRGAEQIYIPVLIKKREKEKGLDRSKMVALSNYFFDTTQGHTQINCCVAKNVYTEEAFDTGVKADFKGNFDLEKLEQAILEAGPANVPYIVSTITCNSAGGQPVSIANLKAVYEIAQRYDIPVIMDSARFAENAYFIQQRERDYRNWSIEEITREAYKYADGLAMSAKKDAMVQMGGLLCFKDESFFDVYTECRTLCLVQEGFPTYGGLEGGAMERLAVGLYDGMRQDWLAYRINQVEYLVNGLEAIGVICQQAGGHAAFVDAGKLLPHIPADQFPAHALACELYKVAGIRAVEIGSLLLGRDPATGKQHPCPAELLRLTIPRATYTQTHMDFIIEAFEKVKANARNVKGLEFTYEPPVLRHFTARLKEKA
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: HEMA_CVHN2
Sequence: MLIIFLFFNFCYGFNEPLNVVSHLNHDWFLFGDSRSDCNHINNLKIKNYGYLDIHPSLCNNGKISSSAGDSIFKSYHFTRFYNYTGEGDQIIFYEGVNFNPHHRFKCFFNGSNDVWIFNKVRFYRALYSNMALFRYLTFVDILYNFSFSIKANICNSNILSLNNPIFISTNYSKDVYFTLSGCSLYLVPLCLFKSNFSQYYYNMDTGFAYGYSNFVSSDLDCTYISLKPGSYKIFSTGFVLSIPTKALCFNKSKQFVPVQVVDSRWNNLRASDTSLSDACQLPYCYFRNSSGNYVGKYDINHGDNGFTSILSGLLYNVSCISYYGSFLYDNFTSIWPRFSFGNCPTSAYIKLNCFYDPLPIILQGILLFLALLFIVFLLFLVYHG
What is the function of this protein?
Structural protein that makes short spikes at the surface of the virus.  Contains receptor binding and receptor-destroying activities.  Mediates de-O-acetylation of N-acetyl-4-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells.  This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell.  May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one.  May become a target for both the humoral and the cellular branches of the immune system.
What are the official names of this protein?
Hemagglutinin-esterase, HE protein, E3 glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the influenza type C/coronaviruses hemagglutinin-esterase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In infected cells becomes incorporated into the envelope of virions during virus assembly at the endoplasmic reticulum and cis Golgi. However, some may escape incorporation into virions and subsequently migrate to the cell surface.
Protein: LOXL3_MOUSE
Sequence: MRAVSVWYCCPWGLLLLHCLCSFSVGSPSPSISPEKKVGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHVLCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCRGTEGSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHQLQVEEVRLRPAVEWGRRPLPVTEGLVEVRLPEGWSQVCDKGWSAHNSHVVCGMLGFPGEKRVNMAFYRMLAQKKQHSFGLHSVACVGTEAHLSLCSLEFYRANDTTRCSGGNPAVVSCVLGPLYATFTGQKKQQHSKPQGEARVRLKGGAHQGEGRVEVLKAGTWGTVCDRKWDLQAASVVCRELGFGTAREALSGARMGQGMGAIHLSEVRCSGQEPSLWRCPSKNITAEDCSHSQDAGVRCNLPYTGVETKIRLSGGRSRYEGRVEVQIGIPGHLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNVTEVVMSGVRCTGSELSLNQCAHHSSHITCKKTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQIV
What is the function of this protein?
Protein-lysine 6-oxidase that mediates the oxidation of peptidyl lysine residues to allysine in target proteins (PubMed:26954549).  Catalyzes the post-translational oxidative deamination of peptidyl lysine residues in precursors of elastin and different types of collagens, a prerequisite in the formation of cross-links between collagens and elastin (PubMed:26307084).  Required for somite boundary formation by catalyzing oxidation of fibronectin (FN1), enhancing integrin signaling in myofibers and their adhesion to the myotendinous junction (MTJ) (PubMed:26954549).  Acts as a regulator of inflammatory response by inhibiting differentiation of naive CD4(+) T-cells into T-helper Th17 or regulatory T-cells (Treg): acts by interacting with STAT3 in the nucleus and catalyzing both deacetylation and oxidation of lysine residues on STAT3, leading to disrupt STAT3 dimerization and inhibit STAT3 transcription activity (PubMed:28065600).  Oxidation of lysine residues to allysine on STAT3 preferentially takes place on lysine residues that are acetylated (By similarity).  Also able to catalyze deacetylation of lysine residues on STAT3 (By similarity).
What are the official names of this protein?
Lysyl oxidase homolog 3, Lysyl oxidase-like protein 3, Lysyl oxidase-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the lysyl oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Cytoplasm. Nucleus. Note=It is unclear how LOXL3 is both intracellular (cytoplasmic and nuclear) and extracellular: it contains a clear signal sequence and is predicted to localize in the extracellular medium. However, the intracellular location is clearly reported and at least another protein of the family (LOXL2) also has intracellular and extracellular localization despite the presence of a signal sequence.
Protein: RL14E_THESM
Sequence: MPAIDIGRLAVVIAGRRAGQKVVVVDIIDKNFVLVTGAGLNKVKRRRMNIKHLEPLPEKINIERGADDEAVKAALEQAGISLE
What are the official names of this protein?
50S ribosomal protein L14e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
Protein: Y1906_KLEP3
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDPASNPRLRAAVDKALSNNMTRDTLNRAIARGVGGDEDANMETIIYEGYGPGGTAVMVECLSDNRNRTVAEVRHAFTKTGGNLGTDGSVSYLFSKKGVISFEKGDEDTIMEAALEAGAEDVVTYDDGAIDVYTAWEEMGAVRDALEAAGLKADAAEVSMIPSTKADMDAETAPKLLRLIDMLEDCDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein KPK_1906.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2_CUCSA
Sequence: MTRRYWNIHLEEMMEAGVHFGHGTRKWNPRMAPYISAKRKGIHIINLTRTARFLSEACDLVFDAATRGKQFLIVGTKNKAADSVARAATRTRCHYVNKKWLGGMLTNWSTTETRLHKFRDLRTEQKTGGLNRLPKRDAAMFKRQLSHLQTYLGGIKYMTGLPDIVIIVDQQEEYRALQECITLGIPTICLIDTNCDPDLADISIPANDDAIASIRLILNKLVFAISEGRSSSIRNS
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.