PharMolix/UniProtQA huggingface dataset:
Protein: CADD_CHLPN
Sequence: MTSWIELLDKQIEDQHMLKHEFYQRWSEGKLEKQQLQAYAKDYYLHIKAFPCYLSALHARCDDLQIRRQILENLMDEEAGNPNHIDLWRQFALSLGVSEEELANHEFSQAAQDMVATFRRLCDMPQLAVGLGALYTYEIQIPQVCVEKIRGLKEYFGVSARGYAYFTVHQEADIKHASEEKEMLQTLVGRENPDAVLQGSQEVLDTLWNFLSSFINSTEPCSCK
What is the function of this protein?
Involved in de novo para-aminobenzoate (PABA) biosynthesis.  Acts as a self-sacrificing or 'suicide' enzyme that utilizes its own active site tyrosine residue(s) as the substrate for PABA synthesis.  The side chain of the tyrosine residue is released from the protein backbone via cleavage of the C(alpha)-C(beta) bond, leaving a glycine in place of the original tyrosine residue.  Reaction requires O(2) and a reduced dimetal cofactor.
What are the official names of this protein?
4-aminobenzoate synthase, para-aminobenzoate synthase, PABA synthase.
What is the protein family that this protein belongs to?
Belongs to the CADD family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted into the host cytoplasm, where it co-localizes with Fas in the proximity of the inclusion body.
Protein: TRPD_LEGPH
Sequence: MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAQVMRQLAHKIDLGNPLIDIVGTGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGSADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQHARAARQQLGIRTLFNLLGPLINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRDGNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYCAKDGISFDAAIEEARIAIDSGKANLCFNKLRLLTQTLNKESNHE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ELN_SHEEP
Sequence: FGLGGVGGLGVGGLGVGGLGAVPGAVGLGGVSPAAAAKAAKFGAAGLGGVLGAGRPFPIGGGAGGLGVGGKPPKPFGGALGALGFPGGACLGKSCGRKRK
What is the function of this protein?
Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely.  Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).
What are the official names of this protein?
Elastin, Tropoelastin.
What is the protein family that this protein belongs to?
Belongs to the elastin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Extracellular matrix of elastic fibers.
Protein: RTEL1_DROAN
Sequence: MPESLIAGIPVHFPFEPYPVQRAYMEKVIQCLKDGTNGVLESPTGTGKTLSLLCSSLAWIRTRQSEHQQQMIKLDKGADLLGGGAGGGPELSDLAKTMGKANNWGVPKVIYASRTHSQLTQAMRELKRTAYSNMRSVVLGSRDQLCIHPEVSREVGNSNKVNMCKLRVHSKTCTFQLRVESKKDHPDFRGPSIMDIEDLIKVGQKLKMCPYYASKELVPQADITFMPYNYLLDPKARKANKIELGNTIVILDEAHNIEKICEESASVQIKSSDVAIAIEDVTHIMKAFASDSPQDMAGDEPKDFTIDDLMLLKEMLLDLEKAIDAVAVDNPIDGATYPASMIYELLGKANFTYGNVATIVALLDKLVQYLMVASQQQMSLRKGGSFTLLSDLLTIVFANKESVMGKVHASFKVHVQVEESKQPQGKQAPAKQAGGWLSKASLTNGSTGKVAKIINFWCFNPGFGMEQLLNTQVRSVILTSGTLAPLKPLIAELAIPVAQHLENPHIVDQSQVYVKIIGTGPDRQPLISNYTNRDNPKYISSLGQTILNVSRLVPDGLLVFFPSYPMLNKCVDAWQASGLWADIASKKPIFLEPRGKDQFTSTMEEFYQAIRDSKGACFMAVCRGKVSEGLDFADRNGRAVIITGLPFPPLKDPKVILKRRYLESNRTRENQLLSGNEWYNLEATRAVNQAIGRVIRHRNDYGAILLCDSRFKDAAQVQQLSKWIRGHLGDRPQCSPFGPIVRELRQFFKNAETTMKQPDERESGAPLETVIKKEDEPLAPISQIKREPGSNATFKAANETAIKVEMANSIKSWSPDDYACAAGRKLGGSSAPNAMDFMSRLDSNVSSIDFNCMDSRNGSNSSGLVKIHKRERSSPPGSSQSSSQTAKKRYKLVENISTIKVEPPVEVKKEVPESRAAFLREIRSLVGQDQFRAFGQALLEYKDGSKDKFEALMKVVFEVLGGPRCRHLLVGMRKYIKADDKPEFDIRLAKLEKS
What is the function of this protein?
ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability.  Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis.  Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates.
What are the official names of this protein?
Regulator of telomere elongation helicase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD3/XPD subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMA_PSE14
Sequence: MRDPAPSNSEMKRVIVGMSGGVDSSVSAVLLMEQGYQVEGLFMKNWEEDDGTEYCTAREDLADAQAVCDKIGIKLHTANFAAEYWDNVFEHFLEEYKAGRTPNPDILCNREIKFKAFLDYALMLGADLIATGHYVRRRDIDGRTELLKGLDPNKDQSYFLHAVGGEQIARTLFPVGELEKPEVRAIAEKHGLATAKKKDSTGICFIGERRFTDFLRQYLPAQPGEIKTTEGEVIGRHSGLMYHTIGQRQGLGIGGLKDASDDPWYVLVKDLDNNELIVGQGNDHPWLFSRALVSSEIYWVNPIDLSSPRKLTAKVRYRQGDQPCTLEKTADGYRATFDDPQRAVTPGQSVVFYDGEICLGGGVIEIAEPWTSKDKR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT2_CLOP1
Sequence: MELLKDKIKKEGRVTEDNILMVDSFLNHQMDVEFFNEVGKEFKDRFKNDQIDKILTIESTGIGLGIITAQYFDNVPVVFGKKIERLPRNKREEVFNSEVYSFTKKTIYNVVVDKKFIKPGEKILIVDDFLANACAVFGLIDVVKQAGAEVVGVGIVIEKGFQSGRAHLEDKGIRVESLVTIDKIEDGEVYFK
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase 2, XPRTase 2.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDB_CALS4
Sequence: MSIRFIYGRAGSGKTYFCLEEIKHKLNDGANHPLILLVPEQFTFEAEKYLLDMIERDEKMRAQVLSFKTLANRVFVEVGGLARQHMKACGKSMVIYKVLEENKEKLKVYSKASRQQGFVKKISEAITEFKRFDVTPFQLIDASEKIEKLGLKEKLEDLALIYSSFEEVLHKNYIDEEDELDLLSKKLEKSLQFEGAEFWIDGFTGFTPKQYKVIEKLLKKASRVSVTLTLDPSIDSIDPTHLFYTTKKTEEKLIKICETNGISVEEPVNLNKGIPKRFEHNKELAFLEKNFFSHPYEIYNEETKNISIFKATNMYSEVEEVARDIARLIRDEHMRYSDIVVATKDLKRYYKLVKAIFSHYGIPHFIDLKINITNNPIIVYVISIFEIYLKNWSYESVFRYLKTGFTGIDKEEINLLENYVLANGIKGNKWKERWEYRIDYKTDSLLMEEREKQIINKVNEVRERVYLPLEKFYTRFSHSKNVKEACEVLYDFLVENKLPEKIEKFIEEFKNRGEFDTANQYAQIWDIVVDVLDQMVEVLGEEKISLEQFARLISIGFDEYQIASIPPALDEVLVTSVDRMKSHNSKVLYLLGANDGVFPASSFEEGIFSDEERNLLSSLDLELDRDTKAKVFEEQFLVYTALTSASEFLKISYPIADHEGRSLRPSIIISRLRRIFPKIKVSTNIVEMDTDEENLNRVTVPLPTFNEMIKSFKKWNITGKIHPIWLEVYKWYRTKDEWKKKLEDTLEGFVYDNQIKRIPPLKIKKLYGEEMEFSVSRLEKYAACPFAYFVQYGLKAKERKIYGFEPPDLGIFMHNVLNEIAKALEKEELTWQEIDKEWCNDAVDIIVEEMVDKIPGYILKSSSRYRYLANRLKRVLSKAVWIISEHMKRSSFVPLGHEVAFGENQKYPPIKIVLSNGEEIKLIGRIDRVDVLEKEGETYVRIIDYKSGDKTLDLSDVLYGLELQLLVYLDAILESAFEGKANLSPAGIFYFKIDDPIVRADKDISDEELYKEIMKRLRLEGFVLKSLDIIREMDKLIEGTSYVIPASINKDGTIGKNTKGLTEEQFEILRKFVKKKSKKLAEEMLQGDISILPYKKEKETACQYCPYSSICKFETNFKGNDYRRIESKEEKLWSIFEEEVKEDGSQVDGRTEGSDNNEG
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: RUVA_VEREI
Sequence: MIGKLTGTLLEKNPPEVLLDCHGVGYEVNVPMSSFYNLPAVGERISLLTQFIVREDAQLLYGFATAPERQAFRALIKITGVGPRMALSILSGMSVADLAQAIARQEAARLVKVPGVGKRTAERLLLELKGKLGADLGASHGPAVSGAQADILQALLALGYNDKEAAAALKALPAQVEVSDGIKWALKALTK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: Y3997_SHEON
Sequence: MEKIFERLMYASRWIMAPIYLGLSLVLLGLGIKFFQEIFHILPIIFEMTEVDLVLVTLSLIDITLVGGLIVMVMFSGYENFVSQLDVGEDSEKLSWLGKLDSGSLKNKVAASIVAISSIHLLKIFMDVKNIDNDKIMWYLLIHITFVLSAFAMGYLDKMTRK
What are the official names of this protein?
UPF0114 protein SO_3997.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y255_LEGPA
Sequence: MTMMITTGNSFDGKVIKQCLGIVRGIVVRSPTISQGLMGGLKSIVGGKIGAYSQMCEHAREEAFQLMIEHAQALNANGIIAMRYDTGEIGQAGTEVLCYGTAVII
What are the official names of this protein?
UPF0145 protein lpp0255.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: QUEA_STRPG
Sequence: MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFDHIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRLKVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLEDAERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDNLDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGGKFQGDIQADSGWTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFSFGDAMFVN
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_PSEPF
Sequence: MERQLDAYCEHLRSERQVSPHTLSAYRRDLDKVLGWCIKQNIGSWQALDIQRLRSLIARLHAQGQSSRSLARLLSAVRGLYHYLNRECLCDHDPATGLAPPKGERRLPKTLDTDRALQLLEGAVEDDFLARRDQAILELFYSSGLRLSELTGLNLDQLDLADGMVQVLGKGSKTRLLPVGKKAREALEQWLPLRALTNPSDDAVFVSQQGRRLGPRAIQVRVKLAGERELGQNLHPHMLRHSFASHLLESSQDLRAVQELLGHSDIKTTQIYTHLDFQHLAAVYDSAHPRAKRMKGDDS
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZPBP1_CHICK
Sequence: GGLLLLGLLIVLLQAAPAVQCLRSAESRSNSLKIVGSILFPVKVYVKLDHSSPHILCVTNRLRNSELIDPVFRWNGPSGYLSSANSSVQISPTGTLILGHFRSDLSGVYTCSLVYKLIAAQPDKRLTIKYHIYAYSDPQYYYELTVQYHAAPCNSFHNTSFGRALLQILSKLVADLSCEVSLIKSECHHVKMQRGGLQSEMFFKFSVTCLDTENNKLCRQSACDKPHRLHKAKDLIERFFKREVEIRKKSTEPLPEIYYIEGTLQMVWVDRCYPGYGINAVRHPDCPECCVICSPRSYNPSNGIHCLQCDTSLIYGATTC
What is the function of this protein?
Plays a role in sperm morphogenesis and in sperm-oocyte interaction during fertilization.
What are the official names of this protein?
Zona pellucida-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the zona pellucida-binding protein Sp38 family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Peripheral membrane protein.
Protein: KTHY_ACIBS
Sequence: MFISFEGTEGVGKTTLIRKIHQHFEEQGKQVVLTREPGGTPLAEQIRSMLLAVNHDENMSHDTELLLIYAARAQHLQQVILPALESNKIVLSDRFTDASFAYQCSGRGLSQDKLQLLNQNFVSRMPEVTFWLDAPIELGMNRARERGALDRFEQEKLSFFTKVREGYETLWKAEPERIKRLDATQSPDQVFEQALQYLA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RS18_HAEIE
Sequence: MARYFRRRKFCRFTAENVVEIDYKDIATLKNYISESGKIVPSRITGTRAKYQRQLARAIKRARYLALLPYTDNHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: O163_CONIM
Sequence: MKLTCMMIVAVLFLTASIFITADNSRNGIENLPRMRRHEMKKPKASKLNKRGCLPDEYFCGFSMIGALLCCSGWCLGICMT
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like 3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: K118A_POLSE
Sequence: MSFRSQTSSTTSMRPVSSYSSRSISLHRSVPLGSSASVVGGAGGHGARISSGGFGLASGYSSGSSFSMSVKGSGLFNNEKETMQILNDRLASYLETVRNLEQANSKLELQIRETLEKRGPTTQDYSAYEKVVEDLKSQIYDMTVNNARLVLQIDNARLATDDFRVKYESELAIRQSVESDIIGLRKVIDDTNINRMNLETDIESLKEELIFIKRSHQTDVEELRKHISECGVQVDVDAPKGQDLSKIMEEIRAQYETIIQKNREELKDWHNSQILIVETEVKENTEALQKSRTEVTELRRQFQTLEIDIESLRTMKASLEANLHDVEMRNNMEMEGFNFIIRQQEADLQQLRTSIQAQVHEYQALLNIKMKLEAEIATYRRLLDGEDFRLQDALAVQTTKVQKKITVTETVVDGKVVSQSSEVQEIKK
What is the function of this protein?
When phosphorylated, plays a role in filament reorganization.
What are the official names of this protein?
Keratin, type I cytoskeletal 18-A, Cytokeratin-18-A, CK-18-A, Keratin-18-A, K18-A.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RADA_HELPJ
Sequence: MAKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQTQKEVLNALKKPLPQVQKSVSIAEIEHEEVIKFSSTQSELDIVLGGGIAKGGLYLVGGSPGVGKSTLLLKVASGLAKNQQKVLYVSGEESLSQIKMRATRLDCIEEELYLLNEINWPVIKANMESENYFACVIDSIQTLYSPEISSAPGSISQVREITFELMRLAKTRDIAIFIIGHITKEGSIAGPRVLEHMVDSVLYFEGDPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSKEEPMEGSAITITLEGSRALILEIQALVSECSFGAPKRLANGFDTNRLNMLIALLEKKLEIPLNRHDVFINVSGGIKISEPACDLAVIASILSSFKNRKIDNKTAFLGEVSLNGRILEAPNLNARLKEMENYGFLKAILPKKPSQKTSIKCYEANVVGKIVEWM
What is the function of this protein?
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks.  Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster.  Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB.  Does not have RecA's homology-searching function.
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: ABC4_SCHPO
Sequence: MENFHHRPFKGGFGVGRVPTSLYYSLSDFSLSAISIFPTHYDQPYLNEAPSWYKYSLESGLVCLYLYLIYRWITRSFTVKQTVGSEFSGLRKAHGILLWLLSILFLGMTAFMFVNDAFPTAFSDPPVKICLLAYSVHLFLLHSLRMIYPRARPTLYHAAVLLNLLLLPPIFHFYSYPFFFVDHPPLSSYSPFLWFYFFITIVGNFIPLFTPRVWYPLFPEDNYQPSAEQVCSMFNFACSYGYLNPLVLTAKRRVVEVDDTPVIPDYDKNKAWTYRFERMKTPSLFITIHKIFWRQILGMGVSSFMVSVCQFLSPIALNRLLKHLESPSSSSVNPLVWIVLLLTGPFLTSLFTQFYLFMSTRYLARSYTTLVQQIYNKVIRSRFVQNKSGDSKVGRSNNLISTDVDDIGEIREFIHIIVRAPVEIAGSIYLLQKLLGWSAYVGLALTVLTCSVPIVLGPLVAKLTLRANRATDSRIELMSELLQSIRITKFFGWELPMLDRVKQRRQVELNRTWKLLLMEICIQVLVESLPVFSMFATFVVFTTIMGQTITPSIAFTSISLFSFIRTQFSWIAYLMRQIVQIFVSIGRVSDFLNDPDEVDPVNTIEDTSQEIGFFNASLTWVSNPSPGDFCLRDLNIVFPRNKLSIVIGPTGSGKSSLISALLGELSLNKGSYNLPRSKGVSYVSQVPWLRNATIRDNILFDYPYIEERYKKVIQACGLLTDLQSFVASDLTEIGEKGVTLSGGQKQRIALARAVYSPTSIVLMDDVFSALDIHTSNWIYKHCFQSSLMENRTVILVTHNVHLFMDSAAFIVTVKNGSAFPVTDKSSPLLFLAEQAASASEAAAPDLAAIPIPNEVDDAEAADEKDGKLVEEEQRVTGDVVFSEIFSYMKHFGSGFYVAAVLLFFVTTQATSILIDLWVAFWTNSSVNSPDVNNNKFLFVYGTMLLAYSLLDFLRTVSYDRGAWWASRKLHDSMLESVFGTFASWFDKTPTGRIVNRFAKDIRSIDMNLSGWLFFSINCFLSVAGGILSVSSAMPIFMIPAVIVCLAGYYFGLLYTRAQVGVKRLISIYTSPIFSLLGESIVGVSVIRAFNRQTIFKQMFSERLDNLVRLQSTSYNLNRWVAVRTDGISGLVGAIAGLIALLQKDLSPGVVGFSLNQAVIFSSSVLLFVRSCNSLQAEMNSYERVLEYSKLPQEPAPTIAGQVPATWPKEGDIVFNHVSVSYSAAGPTILKDVNLHINPSEKVAVVGRTGSGKSTLGLTLLRFTHRISGEIYINGRETQSVNLNALRQRISFIPQDPILFSGTVRSNLDPFDELEDNFLNEALKTSGASSMIMAHTDDQKPIHITLDTHVASEGSNFSQGQKQVLALARAIVRRSKIIILDECTASVDDAMDQKIQKTLREAFGDATMLCIAHRLKTIVDYDKVMVLDKGVLVEYGPPAVLYHNNGHFRRMCDGSGITFLPPETRGSKSA
What is the function of this protein?
Involved in detoxification of xenobiotics, and vacuolar sequestration of glutathione S-conjugates.  Together with abc2, required for accumulation of a red pigment (ade pigment) in the vacuole of a mutant affected in the adenine biosynthetic pathway.
What are the official names of this protein?
ATP-binding cassette transporter abc4, ABC transporter abc4, ATP-energized glutathione S-conjugate pump abc4, Glutathione S-conjugate-transporting ATPase abc4.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: STP_BPLZ3
Sequence: MSNFHNEHVMQFYRNNLKTKGVFGRQ
What is the function of this protein?
Anticodon nuclease cleaves the tRNA(Lys).  It cleaves near a pyrimidine base to generate 2':3'-P> and 5'-OH termini.  Stp activates the host prrC protein probably by counteracting prr masking.  Stp also inhibits EcoprrI restriction.  Stp probably alters the conformation of EcoprrI and, consequently, of prrC, allowing activation of the latent anticodon nuclease.  Presumably, stp evolved to offset a DNA restriction system of the host cell but was turned, eventually, against the phage as an activator of the appended tRNA restriction enzyme.
What are the official names of this protein?
Anticodon nuclease activator.
Protein: SMG_VIBC1
Sequence: MMMDILMYLFETYIHSDAELQVEQDELEDELLRAGFQQKDIYKALVWLEELAALQQSDEHSAISTCIASASTRIYTASEMQRLDLECRGFLLFLEQINVLTTETREMVIDRVMGLETNEFELEDLKWIILMVLFNVPGNENAYTLMEELLYTKEQGILH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: RPOB_AGRVS
Sequence: MAQTLSFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPEGGRPDEGLQTVFKSVFPITDFSGASMLEFVSYEFEPPKFDVDECRQRDLTYAAPLKVTLRLIVFDIDEDTGARSIKDIKEQSVYMGDMPLMTNNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKSHSSGKLLFAARVIPYRGSWLDIEFDAKDIVHARIDRRRKIPVTSLLMALGMDGEEILSTFYSKSDYKRDGKGWRVPFQAETLKGSKTLVDMVDADSGEVVVEAGKKLTPRLLRQLQDKGLKALKATDEDLYGNYLAEDIVNFATGEIYLEAGDEIDEKTLPIILDAGFEEIPVLGIDHINVGAYIRNTLAADKNENRQDALFDIYRVMRPGEPPTMDSAEAMFNSLFFDSERYDLSAVGRVKMNMRLDLEVADTVRVLRKEDILAVVKMLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRLGLLRMERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQVNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKIIDGVVTKDVIYLSAMEEAKYYVAQANAELNAEGKFVEEFVVCRHAGEVMLSPRDTINLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRAEAPFVGTGMEPIVARDSGAAIGARRGGVVDQVDATRIVIRATEDLDAGKSGVDIYRLQKFQRSNQNTCVNQRPLVAVGDILNKGDIIADGPSTDLGDLALGRNALVAFMPWNGYNYEDSILMSERIVSEDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALRNLDEAGIVYIGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTIVEVRVFNRHGVEKDERAMAIEREEIERLAKDRDDEQAILDRNVYGRLLDTLRGQVSIAGPKGFKKGVELNNAVISEYPRSQWWMFAVEDEKVQSELEALRGQYDESKSRLEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPVEDMPFLEDGTHVDIVLNPLGVPSRMNVGQILETHLAWACAGMGRKIGQMLEDYQKHLDITELRTELVDLYASESHDEVARFDDESLLRLADQAKSGLSIATPVFDGAHESDVSEMLTRAGLHTSGQSVLYDGRTGETFDRKVTVGYMYMIKLNHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLSVELENSKLETADTVNPLPDAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: METXS_SACD2
Sequence: MPAPFPEDSVGLVTPQLFHFDQPLALANGRSLDSYELMVETYGELNAEKSNGILICHALSGSHHVAGYHSEDDKKPGWWEHYVGPGKPIDTNRFYVVCMNNIGGCHGSTGPQSINPATGKPWGSSFPFLRVRDWVETQVRLADRLGINQWAAVVGGSLGGMQAMRWALEHPNRLRHCVVIASAMNLTAQNIAFNETARQAIQSDPNFFNGDYLAQSTLPKRGLSVARMIGHITYLSDDGMGKKFGRELRSGSFDRGNDQLVEFQIESYLRYQGSTFSEVFDANTYILMTRALDYFDLAREYNGDAAEAFKQASCKFLVVSFTSDWRFAPERSREIVTALMRANRDVVYGEIDSVHGHDAFLVPNQLRYWELFSAYMNRVEV
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TZAP_PONAB
Sequence: MDGSFVQHSVRVLQELNKQREKGQYCDATLDVGGLVFKAHWSVLACCSHFFQSLYGDGSGGSVVLPAGFAEIFGLLLDFFYTGHLALTSGNRDQVLLAARELRVPEAVELCQSFKPKISVGQAAGGQSGQGPPASQNVNSHVKEPAGLEEEEVSRTLGLVPRDQEPRGSHSPQRPKLHSLAQSESPSSLCGKLKQASKPCPPEDKKLEDCKVLPRPFEAEGAQLQGGSNEWEVVVQVEDDGDGDYMSEPEAVLTRRKSNVIRKPCAAEPALNAGSLAAEPAENRKGTAVPVECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRVHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPHVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDEKMVVVALQPPAELEVGSAEVIVESLAQGGLASQLPGQRLCAEESFTGPGVLEPSLIITAAVPEDCDT
What is the function of this protein?
Telomere-binding protein that acts as a regulator of telomere length.  Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat.  Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres.  Also acts as a transcription regulator that binds to promoter regions.  Regulates expression of a small subset of genes, including MTFP1.  Regulates expression the J and/or S elements in MHC II promoter.  Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A.
What are the official names of this protein?
Telomere zinc finger-associated protein, TZAP, Krueppel-related zinc finger protein 3 homolog, Zinc finger and BTB domain-containing protein 48.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Note=Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. According to a report, preferentially binds to long telomeres that have a low concentration of shelterin complex, competing with the telomeric repeat binding factors TERF1 and TERF2. According to another report, binds telomeres regardless of their length.