PharMolix/UniProtQA huggingface dataset:
Protein: UGGG_SCHPO
Sequence: MRWGFWFAIATLITICYAAKPLDVKIAATFNAPSFSALIAESLYQEKKEGFIWYLNHLSDLLDAENTTEKELYINVVNSLKREYVLSDEELSSLQFSLGLFSGAPKLQAFSSIVQSRSCDCDTWLQLDEESQVCFSDLPKDSPLFSKLYSKNPLDYEVVKTSATGIPYAVVVTSFERDLIPFHELYYKLALEGKCNYVIRYSPPSSSKLNSKLYVKGFGTHVSLKRTDYLVVDDREFPREKGDNPASFTSSRNKRSNERLFGMTSDSLQTVTPDKIAILDLLATQSIASSTDMLTAFRELTQDFPIYAHYLSIQPDVSNDLIEELNQFQSQYVPEGINTIWLNGLSLDLEETDAFSILSLIKKEKDMFDRFEALGIKSSKVLDIVTNEAFANEDSDFKFVKFHCQDDIEDWKAIHWVNEIESNPKYDNWPKSIQILLKPIYPGQLHMLGKQLHTVIYPIFPSSPSSLPLLSELIQFSRRPSPVQTGMVCAANDDDEFAQTVCKSFFYISKESGTDSALKFLYKCLNSDSSADLYSLLEEHLPLSEHDDDTLANLKKDLSSSFFDHYMSKSNSWVNRLGIDSSASEVIVNGRIISHDENYDRSMYGIFLEDIPEVQIAVAEGKISEDDNLLDFILRDASLTRNPLVYPSAKSSIKSIDIKRVLENVGSLNHEDILLIGSSNAKYSFWLVADFNEKEGLEILSLLADLLSENKDANLMLIQEGKNHVVPPLFAKLLSSPKRSSKHLQEILNSSLDPSSGVVNDMDKALKFLKKSKAVVKELGLTGECKSALLLNGRMICSFSVDSLNTADLKMLMQMEYDNYLSKLSNIAGSSRRLKNSRAISFLSSYLKTLESTPMSTSSPTKEEKLFPRDFIYNKLGVGNATFETDDFSKAYYQFVAVLDPLSKDSQKWSAILEAVSKLNGVGVRIHFNPKQTLSELPLTRFYRYSISAEPEFDALGHLEESYVEFDNLPADTLLTMDIEARDAWTVMQKDVDIDLFNIKLEHTSEAEALDSHTAIYELKNILVQGYSQEEFRKSPPRGMQLKLGNLTNSHVTDTIVLSNLGYFQLKANPGVWTLEPMDGRSSQFYEILSLNKKNSYKDPQVIVDSFEGVTLNPVMRRKPGFESADIMDEDLSSHKFFDKIKKSLSFFNFKRKEASINIFSVASGHLYERFLYIMTKSVIEHTDKKVKFWFIENFLSPSFKSSIPAIAKKYNFEYEYITYNWPHWLRKQEEKQREIWGYKILFLDVLFPLELHKVIYVDADQIVRADLQELMDMDLHGAPYGYTPMCDSREEMEGFRFWKKGYWKKFLRGLKYHISALYVVDLDRFRKMGAGDLLRRQYQLLSADPNSLSNLDQDLPNHLQHLIPIYSLPQDWLWCETWCSDESLKTAKTIDLCQNPLTKEKKLDRARRQVSEWTSYDNEIASVLQTASSQSDKEFEEKDNNSSPDEL
What is the function of this protein?
Selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.  Unfolded, denatured glycoproteins are substantially better substrates for glucosylation by this enzyme than are the corresponding native proteins.  This protein and transient glucosylation may be involved in monitoring and/or assisting the folding and assembly of newly made glycoproteins, in order to identify glycoproteins that need assistance in folding from chaperones.
What are the official names of this protein?
UDP-glucose:glycoprotein glucosyltransferase, UDP--Glc:glycoprotein glucosyltransferase, UGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: MRAY_ERYLH
Sequence: MLYLIAEWLGFEGALNLIRYQTFRTGATLMTALVIGLIIGPRFINMLRVRQGKGQPIRDDGPQSHLAKRGTPTMGGLMIIVSLVLSLVLWMDLRSPFVWACLAVTVGFGLIGFLDDLDKVTKNSHRGVSAKVRLLMEFLVAGIASYIIVSQINTWLYVPFVSDRAIPLGPFYYVFAAVVIVGAGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRVDYSEYLGIPHVPGAGELAIFCAAIMGAGLAFLWFNAPPAAVFMGDTGSLALGGALGAIAVASHHEIVLAIVGGLFVFEALSVIIQVFWFKRTGKRVFRMAPIHHHFEQLGWSESKVVIRFWIVSIVLALMGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL17_BURTA
Sequence: MRHRHGLRKLNRTSSHRLAMLRNMSNSLIEHEVIKTTLPKAKELRKVVEPLITLGKKPSLANRRLAFNRLRDRDSVAKLFDVLGPRFANRPGGYLRILKFGFRVGDNAPMALVELLDRPEVEETENVQEAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: TWST1_PANTR
Sequence: MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGGGAGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALPKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASYVAHERLSYAFSVWRMEGAWSMSASH
What is the function of this protein?
Acts as a transcriptional regulator.  Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction.  This interaction probably involves the basic domains of both proteins.  Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B.  Regulates cranial suture patterning and fusion.  Activates transcription as a heterodimer with E proteins.  Regulates gene expression differentially, depending on dimer composition.  Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression.  Heterodimerization is also required for osteoblast differentiation.  Represses the activity of the circadian transcriptional activator: NPAS2-BMAL1 heterodimer (By similarity).
What are the official names of this protein?
Twist-related protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUR7_BORBR
Sequence: MTSALHESSIKSLPLLGRGKVRDMYAVGDDKLLIVASDRISAFDVILDDPIPGKGQVLTELTDFWLRKLAHILPNHSTGIQPEDVVAPDEVDQVRGRAVVVKRLKPILVEAVARGYLIGSGWKDYQASGSVCGIALPAGLQQASQLPEPIFTPAAKAEFGMHDENVDFAHVVKEVGQEMAERIRDVTLRLYGEAARFAATKGIIIADTKFEFGLDDNGTLHLMDEVLTPDSSRFWPADGYRVGISPPSFDKQFVRDWLETQPWDKTPPAPRLPRDVLEKTAAKYREALDRLLA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: YACL_ECOLU
Sequence: MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQAAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: QUEC_COXBU
Sequence: MKKAVILISGGLDSTTCLAVAKSKGFSCYALSFDYGQKHHSELVAAEKIAAHFNVVRYEVVTLSIGKLGGSALTDNSLDVPDYGGNESIPITYVPARNTIFLSIALGWAEILDAESILIGASAIDYSGYPDCRPEYIAAFQNLANLATKRGIEGHSIKIEAPLIHLSKAETIKLGYSLGVDYSMTVSCYRANEEGLACGYCDSCELRKKGFKEAEIKDPTQYITKV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MURI_BIFLO
Sequence: MSSSAPIGVFDSGLGGISVARQIAKDMPAEHVLYFGDSANAPYGIKTPEQVRALSFDIVERFVRQGVKAVVIACNTATSAAVNDLREHYDIPIIGMEPALKVACDRGDVPSDPHHIPQRVIVAATPLTLRERKFAKLMDRFDSNNTIFKEPCPDLVEIVESGRLGDHDLVMRTLHGYFDQYDMEHIDSVVLGCTHFVFYRDYFRELLPERAAVIDGNEGTVRHLGVVLESLGKLAPEDATGGVELANSDPSERIAELSRKLLNV
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PYRG_STRP6
Sequence: MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKERKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQMKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVEQGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTEWSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDVTVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFARHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAYNNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYHPELQSRPNRPEELYTAFVTAAIKNSN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: A21_LOXSP
Sequence: WIMGHMVNAIWQIDQFMDLGVNSIEFDINFDKSANPIYTYHGVPCDCFRSCLKWEYFGDFLTALRHRTTPGDKLYKEKLILFVFDMKTNSLYDNQAYTAGVNMANNIFKYYWNNGNNGGRSYFILSIPNLNHYNLIKGFQETIKSKGHPELLEKVGYDFSANDDIPDVEKAYQKVGVTGHVWQSDGITNCLPRTLTRVQAAVKERDSGGVINKVYYWTADKYSTTRDALDAGVDGIMTNYPYVLNDVLKENAYKNKFRLANYEDNPWVTFKP
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LspaSicTox-alphaII1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: METAA_ACET2
Sequence: MPIKIPDSLPAKEVLTNENIFVMDEHRALHQDVRPLRIAILNLMPTKITTETQLLRLIGNTPIQVEIELLHPKTHVSKNTPEEHLTKFYKTFDEVKDEKFDGLIITGAPVEQMEFEEVNYWEELKKIMDWSVHNVYSTFHICWGAQAALYHHYGIKKYPLKEKMFGIFPHRICKPNTMLLRGFDDCFYAPHSRHTEVRREDIEKVGEIDILSDSEEAGVYIMKTRGGRQVFVTGHSEYDQFTLKEEYERDLAKGLKIKMPKNYFPDDDPTKPPVVNWRGHANLLFSNWLNYYVYQETPFDLNELK
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_NITMU
Sequence: MLIIPAIDLKDGHCVRLKQGVMENVTVFSEDPAAMARHWLDQGARRLHLVDLNGAFAGKPKNELAIRDIVDAIGDEIPTQLGGGIRDLETIERYLDDGITYIIIGTAAVKTPGFLHDACNAFPGHIMVGLDAKDGKVAVNGWSKVTGHDVVDLAKKFEDYGVEAIIYTDIGRDGMLSGVNLKATLELARALTIPVIASGGVSSLDDVKALCEMEPEGIAGAITGRAIYEGTLDFKVAQELADELSTQSSPRDTTILF
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_AZOC5
Sequence: MNVNVPVPSTLADPLVIAGRTFSSRLFLGTAGYPNQKVFLDALEASGSEMATASIRRMSLEGYEESLADLLTGRVHILPNTAGCQTAKDAILTAELAREALETDWVKLEVIGDRELLYPNVEELLKATEELVNRGFVVLPYCNDDPVTCQKLADLGAATVMPLGSMIGTGLGIANPHMIELICARSPVPVVLDAGIGTASDAAQAMELGCAAVLLNTAVSKAHDPVRMARAFRYAVEGGRLARLAGRIPKKLHAEASSPEFGLVGS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_STAAW
Sequence: MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIKSKSIEK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SMST_SANMU
Sequence: MENQKMPISSVPNLKDLNMISRPIANFPPSIWGDRFINYTCEDENDQTQKERQVEELKEQVRRELAATVDKPLQQLNIIDATQRLGIAYLFENEIEESLKHIYLHTYVENNCFEGSDDLYSVALWFRLLRQNGYKVSCDVFNKFRDNEGNFKNNLMEDAKGLLELYEATHVSIHGEEMLDDALEFTKTRLESVVSHLNYPLAEQVRHALYQPLHRGLPRLEAVYFFRIYEAHASHNKALLKLAKLDFNLLQSFHKKELSDIARWWKSLDFAAKFPFARDRLVEGYFWVLGVYFEPQYSLARKIIIKVFTMISTIDDIYDAYGTLDELKLFTKAMQRWDVGSLDQLPEYMKPCYKSILDVYNEIEEEMANQGSLFRMHYAKEVMKTIVEGYMDEAKWCHEKYVPTFQEYMSVALVTSGYTFLTTISYLGMGEIASKEAFDWLFSHPPVIEASESVGRLMDDMRSHKFEQERGHVASGIECYMKQYGVTEEEAHDEFRKRLVKAWKDINEECLRPYRVPKPLLTRILNLTRVIDVIYKNEDGYTHVKKAMKDNIASLLIDPVIV
What is the function of this protein?
Sesquiterpene synthase.
What are the official names of this protein?
Probable sesquiterpene synthase, SmSTPS.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: HEM1_COXBU
Sequence: MPLLVCGINHQSAPLTVREKLVFTPERTPLALQSLLAEKAVNEALLLSTCNRTEIYTTVDEAATILRWLSKQPQLSGIDLRSFCYARRDIEMVRHVMRVGSGLDSMVLGEPQILGQMKQAYLLARRIGAVGSELGRLFPAVFAATKRIRSETAIGANPVSIAYAVVQLAKRIFSHLNQCQILLIGAGETIELVFSHLYNQGARHFFIANRTLTRAKQIAEPYHAQAIRLSDIPTYLPKVDIVISATMSQLPLVGKGAVESALRQRKRRPLFMADLALPRDIEPETAQLEDVYLYNIDDLQTLIAQNRQTREAAAKQAEAMVEMQAIHYMRQLQVHKAGDTIRRFRERVEMLRDQELEKALAHFQRTNDPKAVIAHFAHNLTNKILHQPTTKLRQAAYEDQVQLLLSAKELFDL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PSRP_VIBVU
Sequence: MQTEKQSRDVFYVSDGTAITCETLGHVVLGQFPFVANEKTFPFVESEEKLTELIKHIEISFQTNGIKPLVFFSLVLPDLKARLMESPAYCYDVLESIVQRVKDDIQMEPTPKLQRSRSVGKDTDTYFDRIAAIEYTLAHDDGISLKGLELADIILLGVSRSGKTPTSLYMAMQFGLRVVNYPYIDDDIKGLKLLPEFEIHRHKLFGLTIDPERLTEIRENRLAGSDYASTEQCQHELANVEALFRREAIPYINTTSLSVEEISTRVLEKTGLKRRLF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: RR18_LOBMA
Sequence: MNKSKRPFTKSKRSFRRRLPPIQSGDRIDYRNMSLISRFISEQGKILSRRVNRVTLKQQRLITIAIKQARILSLLPFLTNQKQFERSESTPRTTSLRTRKK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TXC6E_CUPSA
Sequence: FLNPFRWVINKYREWKNKKDS
What are the official names of this protein?
Cupiennin-6e, Cu-6e, Short cationic peptide-6e, SCP-6e.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 09 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NHAA2_ERYLH
Sequence: MFYTAATALRDFLKQESAGGIVLMFAAVLALIFANTALADTYFSVLATEIAVTVGGGGIEKPALLWINDGLMAVFFFLVGLEVKREVLTGQLSSWKQASLPLIAAFGGIVLPALVFYGINSGTPENLSGWAIPAATDIAFALGILALLGKRVPVALKALLLAIAVIDDIAAIAIIAIFYTPGVELAMLGAAAITLLILSAFGRAKAGSSIPYIVLGIVLWYFVLKSGVHATLAGVALAMTVPLIDRKGNHMLEHMEHALHSWVAFLVVPIFALANAGVSFEGVELSALFAPLPLGIALGLIVGKQVGIFGFAWLAVKTGFAQLPSSVGWLQVWGLSLVAGIGFTMSLFIGNLAFADPAQINAVKIGVLSGSLIAALVGIAILVLGAKAPAAKSADERVQAPA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNLI_VACCW
Sequence: MTSLREFRKLCCDIYHASGYKEKSKLIRDFITDRDDKYLIIKLLLPGLDDRIYNMNDKQIIKLYSIIFKQSQEDMLQDLGYGYIGDTIRTFFKENTEIRPRDKSILTLEDVDSFLTTLSSVTKESHQIKLLTDIASVCTCNDLKCVVMLIDKDLKIKAGPRYVLNAISPNAYDVFRKSNNLKEIIENASKQNLDSISISVMTPINPMLAESCDSVNKAFKKFPSGMFAEVKYDGERVQVHKNNNEFAFFSRNMKPVLSHKVDYLKEYIPKAFKKATSIVLDSEIVLVDEHNVPLPFGSLGIHKKKEYKNSNMCLFVFDCLYFDGFDMTDIPLYERRSFLKDVMVEIPNRIVFSELTNISNESQLTDVLDDALTRKLEGLVLKDINGVYEPGKRRWLKIKRDYLNEGSMADSADLVVLGAYYGKGAKGGIMAVFLMGCYDDESGKWKTVTKCSGHDDNTLRVLQDQLTMVKINKDPKKIPEWLVVNKIYIPDFVVEDPKQSQIWEISGAEFTSSKSHTANGISIRFPRFTRIREDKTWKESTHLNDLVNLTKS
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.  Recruits cellular topoisomerase II to sites of viral replication and assembly (PubMed:18417590).  Contributes to the repair of the viral genome following UV irradiation (PubMed:35404095).
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in sites viral of replication and assembly.
Protein: YXEJ_BACSU
Sequence: MSLINSHQSADSGLNIWSQLFFYTIVTASEWIGGLQKRRKGKGNGEILYEIIGRKLSLCFIRLSFLADIEVALVE
What are the official names of this protein?
Uncharacterized protein YxeJ.
Protein: LSRF_YERPB
Sequence: MADLDDIKDGKDFGIGIPQQNPAFTLKGSGSLDWGMQSRLARIFNPKTNRTVMLAFDHGYFQGPTTGLERIDINIAPLFEYADVLMCTRGILRSVVPAAANRPVVLRASGANSILTDLSNEAVAVAMEDAVRLNACAVAAQVYIGTEHEHQSIKNIIQLIDQGMRYGMPTMAVTGVGKDMVRDQRYFSLASRIAAEMGAQVIKTYYVDSGFERIAAGCPVPIVIAGGKKLPERDALEMCYQAIDQGASGVDMGRNIFQSDAPIAMLKAVHAIVHKNENAAAAYQLFLHEQN
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.
What are the official names of this protein?
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPSB_BACAN
Sequence: MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEAFHKEFEQLKQQNARLKRELEEQKLAATQVPQQPVVQTPVAQPVYNNTNTDILKRLSNLEKAVFGSKLYE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: RECO_BIFLS
Sequence: MSLYRDEGVVLRTSKLAEADRIITVLTRDHGKIRAVAKGVRRTKSRFGARLEPFMRVDLLIAEGRSLDTVSQAESIAAYGAAIVGDYAAYEAANVIVETIDKLVGTERERMTDQYRLLIGALNALAKRAHAPQAIGCSYVMRALALAGWTPRLGTCVVCGAAAPAYLSIASGGVMCEADHTTDARRIAPSALGQFDALVHGDWTVLDAAPVERVVRELVEDWGEYYLERPIRSLRLIDS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RL4_SACEN
Sequence: MSVTLDVRTPDGKTDGTVELPAEIFDVQANIALMHQVVVAQLAAGRQGTHATKTRGQVSGGGKKPYRQKGTGNARQGSIRAPQFTGGGTVHGPQPRDYSQRTPKKMKVAALRGALSDRVRAGQLHVVSHVVGGEQPSTKQARTAVRTWTEAKRVLVVLNKSEETSWLSLRNLQNVHLIDPSQLNTYDVLVNDDVVFTKAAFERFVAGPAKGKTAKAAATSGEAEEANQ
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CYAA_HAEIN
Sequence: MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAIVPLLLHLNHPQLPGYVIHAPSGIASFLASDYQKKWLTNEYGIHYADHKPSTLKSAVNFHEVFPPILGVYVMGSFGSISQTSSSDLDTWICVRDGLSLDEYTLLTQKAKRISEWAMQFNVEINFYLMDQQRFRNEHYADPLTIENSGSAQYMLLLDEFYRSAVRLAGKPLLWLHLWVENEKDYEKEVARLITEGEIDPNDWVDFGGLGQFSANEYFGASLWHLYKGIDSPYKSVLKILLLEAYSKEYPNTCLIARTFKRDLLAGNTNPDHHFDPYIAILAKVTQYLTALSEFKRLDFVHRCFYVKATEDFARYQANNWRIRYMEILAQEWGWSAETVKHLNKRPFWKIKAVKENHDNIMKFLMLSYRNLVEFARKHHIHSSVVPQDINILSRKLYTAFEELPGKVSLLNTQISHNLSEAHLTFVEVRGNKHFKDGWYLINQPIHHIMFSKERVIEYGESLNKLVSWAYFNHLLTEKTELSIFSKNVTLSTLQRFVTNLRQSFPSTIAKQPKNSDLLNQCEIRSLFIAINLTTDPTSKVEEVLTGISSRDLFSFGSLEQSLVGSIDFTYRNVWNEIRTLHFEGQNAILLALKVLSNKIYRGVNRPDSIQVYCYSERYRQDLRQLVMGLVNRCVSIQVGDIQQPCQTSRLRVAGKNWQLFFEDRGISLQEIGNESVCNEAESAVDFDEVLQTPIEDGETNQESRRYPPEMDAFASEGFLQFFFEDNSDHSFNVYILDESNHLEIYRHCDGEKDEKVREINQLYQNAKQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISIVPFKFRQMNK
What is the function of this protein?
Plays an essential role in competence development.
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_STRPF
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: TXB1A_SCODE
Sequence: MFYSHLLFFTFTFACSSSLNRKTKREMDLEDIILDTCHQKAVCAHIQMHLKETYVDELCKCGGGQECPLHWDPNDGHSITLAYNQWKFCSPTSQDLPVCTREQTAREFSYDMKPVSKKVQMFMFFNCLCPENHFYEFFNEREEETGGGQLAIIEERCEKMKQCEKTQICQKIETLQGKFLFKHVKCFCPGDQNCNDDLKKADAIDVGDDGSVQHYMKCH
What is the function of this protein?
Voltage-gated potassium channel inhibitor.
What are the official names of this protein?
Kappa-scoloptoxin(11)-Ss1a, Kappa-SLPTX(11)-Ss1a, Toxin SSD92.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-11 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CUTA_ECOL6
Sequence: MLDEKSSNTTSVVVLCTAPDEATAQDLAAKVLAEKLAACATLIPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.