PharMolix/UniProtQA huggingface dataset:
Protein: MRAZ_SHIBS
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CM32_CONPE
Sequence: MLKMGVLLFTFLVLFPLATLQLDADQPVEQYAGNKQDLNPDEKREMILPALRQWQCCTMAWCDSGCLCCE
What are the official names of this protein?
Conotoxin PnMLKM-013.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SOT8_ARATH
Sequence: MGEKDIPRNLKEEEEEEEENQSEETKSLISSLPSDIDCSGTKLYKYQGCWYDKDILQAILNFNKNFQPQETDIIVASFPKSGTTWLKALTFALAQRSKHTSDNHPLLTHNPHELVPYLELDLYLKSSKPDLTKLPSSSPRLFSTHMSFDALKVPLKESPCKIVYVCRNVKDVLVSLWCFENSMSGENNLSLEALFESLCSGVNLCGPLWENVLGYWRGSLEDPKHVLFLRYEELKTEPRVQIKRLAEFLDCPFTKEEEDSGGVDKILELCSLRNLSGLEINKTGSLSEGVSFKSFFRKGEVGDWKSYMTPEMENKIDMIVEEKLQGSGLKL
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor.  No activity with brassinosteroids.
What are the official names of this protein?
Cytosolic sulfotransferase 8, AtSOT8, Sulfotransferase 4b, AtST4b.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPV5_RABIT
Sequence: MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQEQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTLGHLNLGLDLGEGDGEEVYHF
What is the function of this protein?
Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:10085067, PubMed:11035011, PubMed:12574114, PubMed:29323279).  Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity).  The channel is activated by low internal calcium level and the current exhibits an inward rectification (PubMed:29323279).  A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay (PubMed:11035011).  Heteromeric assembly with TRPV6 seems to modify channel properties.  TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (PubMed:12574114).
What are the official names of this protein?
Transient receptor potential cation channel subfamily V member 5, TrpV5, Epithelial calcium channel 1, ECaC1, Osm-9-like TRP channel 3, OTRPC3.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV5 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Note=Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells (By similarity). The expression of the glycosylated form in the cell membrane is increased in the presence of WNK3 (By similarity).
Protein: NUOI_RUEST
Sequence: MTQIDYTRAAKYFLLQDVWQGFKLGLKYFFAPKATINYPHEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIDAEPREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETREELFYDKDKLLANGERWEAEIARNLELDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: T2R40_CHICK
Sequence: MSSLFSSFCLVIAIFESVVGLLGNGTIVAVSSTSCIRSKILSSYDVIVIFLSLSRFFLQLWMILDFLLIFFCQPSYYEENLFVTFKTVFIFLNSYSFWFAAWLSVFYCVKVASFTQSFLSWLKQRIASLIPWMLITSSLFSFATSLPFFWDSYNAHSNFTTPLTMTNSSKRITTRKTNLIFLILLCNVGIALPSIMLVFSSILLIRSLWRHTRQMQNNATGFRDPSLEALIGAIKTVFSFLLLYITNFIALILILSDTFVPLSTEEAICVVVVAACPAGQSMVLIWSNPRFRELLSSILHYVNSCVRARCS
What is the function of this protein?
Bitter taste receptor (PubMed:25796330).  Binds quinine, dextromethorphan, diphenhydramine, diphenidol, chlorpheniramine, diphenidol, chloramphenicol, chloroquine and coumarin, this latter being a weak agonist, as well as epiquinidine, ethylhydrocupreine and quinidine (PubMed:28811548).
What are the official names of this protein?
Taste receptor type 2 member 40, T2R40, Taste receptor type 2 member 1, T2R1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: USPB_ECOUT
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS19_JANSC
Sequence: MSRSVWKGPFVDSYVLKKAEKSKESGRNEVIKIWSRRSTILPQFVGLTFGVYNGRKHIPVNVTEDMIGQKFGEYSPTRTYYGHAADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PGK_CHLL2
Sequence: MQKKTLSDITIQGKRVLMRVDFNVPLDEEKNITDDKRIVEALPSIKKIIENGGRLILMSHLGRPKGKPNQDFSLTPAAERLSELLDCPVIMAGDCIGTEVMQQVLALQDGEVIMLENLRFHPEEEANDPDFAKELASLGEIYVNDAFGTAHRAHASTEGITRYVQTAVAGYLIEKELMYLGKALQEPERPFVAILGGSKISGKIDVLENLFNKVDTVLIGGAMVFTFFKAQGLGTGNSLVEENKLELALSLIEQAARKNIKLLLPQDIIIAPEISADAESMAVAVNAIPDGMIGVDIGPETRAAYRQEILGARTVLWNGPMGVFEIDRFAEGTIAIAEAMADATAAGATTIIGGGDSAAAVAKAGLADQITHISTGGGASLEFLEGKELPGIAALND
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_MACCJ
Sequence: MKIDYLTLFPEMFDVLNHSIMKRAQEKGIVELNTVNFRDYSGNKHNQVDDYPYGGGQGMVLKPEPIFNAMNAIDKTSKTRVILMCPQGKPFTQQVAESLAQEEHLVFICGHYEGYDERIREHLVTDELSIGDYVLTGGELAAITMTDAIVRLIPESIKEESHLDDSFSTGLLEYPQYTRPADYNGMKVPDVLLSGNHKHIESWRHEMRLKRTFERRPDLLEHYPLTQSDKEYLEHLKRDK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCDA_STRCO
Sequence: MTSPSAPSSAERPRLPGALDGPRLAAAAAEHGTPLWLYDAATIRAQIDRLRRFDVIRYAQKACSNLHILRLMREEGVHVDAVSEGEIERALAAGYRVGGDDEPIVFTADLLNRSTLRRVVELGIPVNAGSPQMLDQVGRAAPGHPVWIRINPGFGHGHSRKTNTGGEHSKHGIWHEHLEESLALVDRHGLDLVGLHMHIGSGVDYGHLESVCETMVKQVRMAGRDIRAISAGGGLSVPYTPGDPEIDTDRYFELWDAARRELVSELGHPVRLEIEPGRFLVAGAGVLAAEVRAQKPVGSNYFVLVDAGFNDLMRPAMYGSNHRVSVLDADGAPRASDARDTVLAGPLCESGDVFTQVEGGDVEPVPVPRTDVGDLVVFHDTGAYGASMSSTYNSRPLIPEVLVDGAETRLIRRRQTVAELLAPELEPGPALSPRPSRDPR
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: DAPA_LACLS
Sequence: MSAKETIEKLKKARIITALVTPFKENGQINFEAFPKLVEDLLASHTEGLILAGTTAESPTLTHDEELEIFASINQLVDGRVPLIAGIGTNDTRDSVEFIKEVAKLGYIDAGLAVTPYYNKPSQEGIYQHFKAIASASDLPIILYNIPGRVVTEILPDTILRLAQLENVIAVKECTSTDNLAYLIENVPEGFLVYTGEDGLAFHAKTLGGQGVISVASHILGQEFFEMFAEIDHGSIQEAAAIQRKILPKINALFSVTSPAPIKTVLNNKGYAVGGLRLPLVACTDQEAKIIIEQIEN
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_SOLLC
Sequence: MGALDEGHYHAEIDNEVSFELGFETQPETLVIQDAVRVLLQGLGEDINREGIKKTPFRVAKALRQGTRGYKQKVNDIVHGALFPEAGLEGGSGQAGGVGGLVIVRDLDLFSYCESCLLPFQVKCHVGYVPSGKRVVGLSKLSRVADIFAKRLQSPQRLADEVCTALQHGIKPTGVAVVLQCMHIHFPNFESAFLDSTSQGWVKITATSGSGVFEDGNADVWTDFWSLLKFRGISIDNAHRRSSGQSWCPSQSCGMPGQANSAMTNAVNSILKSLGEDPLREELVETPSRFVKWFMNFRNSNLEMKLNGFVRSRIDTRSPQGGNFNDGICSELNLSFWSQCEHHLLPFQGVVHIGYHSSDGVNPVGRPLVQSVVHFYGFKLQVQERVTRQIAETVSSFLGEDIIVVVEANHTCMISRGIEKFGSNTATFAVLGRFSTDPVARAKFLQSLPDSGSAGR
What is the function of this protein?
GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: WAPC_PSEPO
Sequence: MSSGGLLLLLGLLTLWAELTPVSSQDRPKKPGLCPPRPQKPPCVRECKNDWRCPGEQKCCRYGCIYECRDPIFVK
What is the function of this protein?
Damages membranes of susceptible bacteria.  Has no hemolytic activity.  Not toxic to mice.  Does not inhibit the proteinases elastase and cathepsin G.
What are the official names of this protein?
Porwaprin-c.
What is the protein family that this protein belongs to?
Belongs to the snake waprin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TMC1_CAEEL
Sequence: MQEAARRASLRKEHTPTNEKFGDLSKQDSLGERASSKLTLDDELYDILYAFGETDAFINKGDKQRETDEDGNPLTRQALLERIRQKKEVIGKLRCQAWSMTRKRRTLKLAQKYLEQHESKVSRSHLYMEEMRKRARLMKRSFSNFKTYLIPWESKIKRIESHFGSVVSSYFTFLRWIVFVNIMITLIALVFVVLPETLADSVANEGRFNRTKTRKQIPANERVHADELAVVWHYDGYLRYSPLFYGYYSDDPFLGNKIKYALPLAYFMVTLTIFAYSFFAILRKMAANARMSKLSGSKAEQYIFNWKLFTGWDYTIGNSETASNTVMAVVIKLRESIADIKKDAHGKFRLLQFSLRVFANIIICAMLGFSIYCIIFAVQKSQVQDDGNLFTKNQVPSVVSTITHVFPMIFDLIGKMENYHPRTALRAHLGRVLILYTVNYITLIFALFEKMTALRDRVNSTSTSSSHRTKRQQGGWNPNMQRPPPYASRAEVRQMSDFLAANTRRFQTVSQRTTRSVTTPFTVAPQFGPFNVNNPNAVFHNGTHSTSFESQILGPKALPIFTPPPRKYPGFTPGNVGQQFGGPDFPRNQVYTKSTPLPRVRTKPPWVYTTTHPPLVQNRAMTTTMSKSAKKGNSKNLDDDILLSNETIQMSEAALRRNHDGHNNDICWETIIGQEIVKLVTMDLIFTILSILVIDLFRGLWIKYCSSWWCWDIETTFPEYGEFKVAENVLHIINNQGMIWLGLFFAPLLPAINNIKLIILMYIRGWAVMTCNVPAREIFRASRSSNFYLGILLIWLLLCTLPVGFVIASMSPSRSCGPFARYQHFYTVVTREIEKRVDQTVLSYIRHIASPGVVIPIILFLILIIYFLFSLVRGLREANTDLQAQLVHERTEEKKKIFELAGGKKNKFEKDRDKKRSNDYIPLIEQRRREPWRQYHEMEADHALASDSSEESDINEDEDDERQPLTAYPLRAIETPPETLQVTAFHPSLGSLIENREMEDEESASGDQLPMIHKSVSFQGPSHMQMRQSISTESCSQISRSAIQVATPEEIRALLRPYLEAKYGIPYQHGIKSFPIDVHTPPNNTPSRRSSKYNSFVSLYEHTRDDHKNFVASTIKETDEDPGKSDKKQTSSKDVAPDFMPWPSADEARALREKMKSKTPLMLTKTTVEEKPKGGKSSESEFRPPVPIHRKYNIQTTEEENEEEETDSAPESSKKRFRISVSPTKTIAPASASRAQHKIVSQASSSSSIPHGRQPDPNKKASLVLPPLRAPRVQFDEDDSPRQID
What is the function of this protein?
Sodium-sensor ion channel that acts specifically in salt taste chemosensation.  Required for salt-evoked neuronal activity and behavioral avoidance of high concentrations of NaCl.
What are the official names of this protein?
Transmembrane channel-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2174_PARDP
Sequence: MTDLSHLARPGAEIAVRVTPRASRNAVILDGEAIRVTVTTVPEDGKANAAVVKLLAKALGVAKSRLVLVRGATARDKLFRID
What are the official names of this protein?
UPF0235 protein Pden_2174.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: Y6915_DICDI
Sequence: MSETENKTTTETPTTTDSTVTTKEVKVPKATSKGNDDYFFVKNVKNQLSNTRTRATVDRLAPTPPLSQAAKRKLIDTKERKEKKEKKEKEPKEPKEPKEKAKKKAKTEKKKDDGDEEEDEEKEEDEEQKEEQSQEEDSEESEEEQNSDEDKKKKKKQAKKVAKKETEPKKKEAKPKKEAKPKKETTKKEKEATTTSSDSTEKKEKEEKPKKEKKISKKDQAAAEKKKDGDDSTTTTATATTTTDDSTENKEEKKDKKTTKKPAAAEKKKVKKDGDDDETAAAATEEKKDEEKSEEKEKKETKKPAAPKKPAAAEKKKTAANPTDKKDGENKDVTPSDDKPAATTTTTTAAAATTTEEPKEKITKPAADKKKAPANKKAEKDQSSSDESANKETTTATTTTTNKDATAPTTTTNKDATAPTTTTTKDNVDEASVKKTANSAPKKEAAKNKSK
What are the official names of this protein?
Uncharacterized protein DDB_G0286299.
Protein: CAGE1_MOUSE
Sequence: MSESETINVNGPSQDFSYSDSPFCMEASFSSSDLLQSETKNVKRGNESTHTFSEDIYSTEGSLLGDINLGNYPESEQNQPANTRLSSLRQFEPICKFHWIEAFNDEMTVEDLRGAFSYSEKPELPSQVYNDAADGSEKPDPFKEESSVESSISENKDELVPAPVRKSPRSLCLNYYRGEAQPLTEAPFVRSAVVDVGLNISQPQSFLDKENVCKNGDNSSDRENCFEQLDLRAIYKAEEPEVSSKEVQNSGEISELSVSHQEEVTEDGVDSLAITSPWSPAGIFKGSGPQDNSLRPDREVSCEGLEPLEEDMALNEALQKLKQTNKKQELQIQDLHGKNLNLENRVQELQTKVTKQHVLVDIINKLKVNIEELINDKYNVILEKNDINKKLQDLQEASAHTKKHLQESKKDKESLQLQVKKIKVHYVRLQERYIAEIQQKNRSASQCLEIEKTLSKKDEELQRLQRHKGELEKATSSALDLLKREKEIREQEFLSFQEEFQRREKESLKERRKLKSRVEKLVAQVKSLLFTCESERAQTMALQRQVEELKLENLELRQLAAKREAQACTPSFEITQSKEQLEEAVEPDITQETKGTHCNLFLNRSSCKENLELQPLKKTSPLASGIHSLLALRIGLLTCQDLATPDAELCQESKKANDIMLQRLKDCQLKKKDLDKELLKHKNRIATLKELIASEKALQAHTIEITDFDADEVKSARDAPVLLAVKLDKYHSLNEELDVLITKLGGLLESKEDHYSRLIEENDKYRRHVGSLINKVTSYEEIIKCADQRLEISHSQIAHLEERNRHLEDLIRMPREKAKRPRPRLDNHPKSLTLISHLEGHHKECSISL
What are the official names of this protein?
Cancer-associated gene 1 protein homolog, CAGE-1, Cancer/testis antigen 3 homolog, CT3 homolog.
Protein: GLMU_POLSJ
Sequence: MATPIDVVIMAAGKGTRMKSALPKVLHQLGGRALLAHVIDCAARLSARQAVVIAGHGAADVEAACAHLTRAAGDARQDLSLKFARQEPQLGTGHAVQQALPLLADDGVTLVLSGDVPLTQPATLRALLEQCDGQRLALLTLNMADPTGYGRIVRAGTQATAQASSQVRAIVEHKDATEAQRGIHEIYSGIMAVPTRLLRGWIHRLDNKNVQSEYYLTDIVKFAVADGVAVVAHQITDAAQVAGVNSPVQLAELERVYQLRQATALMEQGVRLADPARFDVRGTLQCGQDVEIDVNCVFAGQVSLGEGVRIGANCVIANATIAAGAVIHPFTHIDGEKLGVQVGEGALIGPFARLRPGAQLGAEVHIGNFVEVKNSTLAKGAKANHLAYLGDATVGERVNYGAGSITANYDGANKHRTVIEADVHIGSNCVLVAPVTIGQGGTVGGGSTITKDTPPGALSVARGKQVSLPNWKRPVKVSKG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_SYNR3
Sequence: MESTSPALSVSIAVLTALLGLTGFGIYTAFGPPSRQLDDPFDDHDD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RDS3_YEAST
Sequence: MSRHQFDLIMCLKQPGVQTGLLCEKCDGKCPICDSYVRPKRKVRVCENCSFGKQAKNCIICNLNVGVNDAFYCWECCRLGKDKDGCPRILNLGSNRLDRHFEKKKKV
What is the function of this protein?
Required for pre-mRNA splicing.  Involved in regulation of drug sensitivity and may play a role in multidrug resistance.
What are the official names of this protein?
Pre-mRNA-splicing factor RDS3, Regulator of drug sensitivity 3.
What is the protein family that this protein belongs to?
Belongs to the PHF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFP_MANSM
Sequence: MRIIMATYTTSDFKPGLKFMQDGEPCVIVENEFVKPGKGQAFTRTRIRKLISGKVLDVNFKSGTSVEAADVMDLNLNYSYKDEDFWYFMHPETFEQYSADSKAVGDAEKWLLDQAECIITLWNGSPISVTPPNFVELEVVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFIQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-38 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCML1_NOMLE
Sequence: MMSSSSSEIDVVKTRIPTYDEDDNTVLYAYETKPEFVNKELNIVSDASCNTEEQQKTVNDVLIHCQVIYDAMQNLDKKIDVIRRKVSKIQRFCVKSLWTNRKRYGYKKYSYRLAKKLKLKKMKKNEVYESFSYPESYSPTLPVSRCENNSPSNFPRPSFCMEEYRRAEPEEDPILSRTPSPVHPSDFSEHNYQPYYASDGATYGSSSGTCRGNPRADGIHNTYSTDHASAAPPSVTGSLFGNDCYIEEGSITKHPSTWSVEAVVLFLKQTDPLALCPLVDLFRSHEIDGKALLLLTSDVLLKHLGVKLGTAVKLCYYIDRLKQGKCFEN
What is the function of this protein?
Putative Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  May be involved in spermatogenesis during sexual maturation (By similarity).
What are the official names of this protein?
Sex comb on midleg-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARLS_STAA8
Sequence: MTKRKLRNNWIIVTTMITFVTIFLFCLIIIFFLKDTLHNSELDDAERSSSDINNLFHSKPVKDISALDLNASLGNFQEIIIYDEHNNKLFETSNDNTVRVEPGYEHRYFDRVIKKRYKGIEYLIIKEPITTQDFKGYSLLIHSLENYDNIVKSLYIIALAFGVIATIITATISYVFSTQITKPLVSLSNKMIEIRRDGFQNKLQLNTNYEEIDNLANTFNEMMSQIEESFNQQRQFVEDASHELRTPLQIIQGHLNLIQRWGKKDPAVLEESLNISIEEMNRIIKLVEELLELTKGDVNDISSEAQTVHINDEIRSRIHSLKQLHPDYQFDTDLTSKNLEIKMKPHQFEQLFLIFIDNAIKYDVKNKKIKVKTRLKNKQKIIEITDHGIGIPEEDQDFIFDRFYRVDKSRSRSQGGNGLGLSIAQKIIQLNGGSIKIKSEINKGTTFKIIF
What is the function of this protein?
Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence.  ArlS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to ArlR.  ArlS/ArlR affects expression of the multidrug resistance transporter norA and interacts with both Agr (virulence accessory gene regulator) (negatively) and SarA (staphylococcal accessory regulator) (positively) to modulate several virulence factor genes, including ssp (serine protease), spa (surface protein A) and hla (alpha-hemolysin).  Could inhibit biofilm development by a mechanism independent of the presence of the poly-N-acetylglucosamine (PNAG).  Also, Arl proteins are required for the efficient activity of DNA gyrase inhibitors and high osmolarity on spa expression.
What are the official names of this protein?
Signal transduction histidine-protein kinase ArlS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBP1A_ARATH
Sequence: MQNQRLIKQQQQQQQQQHQQAMIQQAMMQQHPSLYHPGVMAPPQMEPLPSGNLPPGFDPTTCRSVYAGNIHTQVTEILLQEIFASTGPIESCKLIRKDKSSYGFVHYFDRRCASMAIMTLNGRHIFGQPMKVNWAYATGQREDTSSHFNIFVGDLSPEVTDAALFDSFSAFNSCSDARVMWDQKTGRSRGFGFVSFRNQQDAQTAINEMNGKWVSSRQIRCNWATKGATFGEDKHSSDGKSVVELTNGSSEDGRELSNEDAPENNPQFTTVYVGNLSPEVTQLDLHRLFYTLGAGVIEEVRVQRDKGFGFVRYNTHDEAALAIQMGNAQPFLFSRQIRCSWGNKPTPSGTASNPLPPPAPASVPSLSAMDLLAYERQLALAKMHPQAQHSLRQAGLGVNVAGGTAAMYDGGYQNVAAAHQQLMYYQ
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as a component of the pre-mRNA processing machinery.  Functions to facilitate the nuclear maturation of plant pre-mRNAs (By similarity).
What are the official names of this protein?
Oligouridylate-binding protein 1A, AtUBP1a, Polyuridylate-binding protein UBP1A, Poly(U)-binding protein UBP1A.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCP2_PHOLL
Sequence: MTTQKTVLITGFEPFGKETINPSWEAAKQLQGRELCGARVEARQLPCVFDVSLACLYAAIDDVQPDLVIAVGQAGGRPNITVERVAININDASIPDNQGNQPINTPIVATGPAAYFATLPINAIVKGLRDAGVPASISQTAGTFVCNHVMYGLLHHLACIYPEIRGGVLHIPYLPEQAARYSGTPSMALETVITALEIAIDEALKNSEDIANNGDTAH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase 2, 5-oxoprolyl-peptidase 2, Pyroglutamyl-peptidase I 2, PGP-I 2, Pyrase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACBP2_SACMO
Sequence: MVSQLFEEKAKAVNELPTKPSTDELLELYGLYKQATVGDNDKEKPGIFNMKDRYKWEAWEDLKGKSQEDAEKEYIAYVDNLIAKYSS
What is the function of this protein?
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters.
What are the official names of this protein?
Acyl-CoA-binding protein 2, ACBP type 2.
What is the protein family that this protein belongs to?
Belongs to the ACBP family.
Protein: Y256_MYCGE
Sequence: MHFNSNFKECFNKIAKKVNSLDSEYYEFSSFIERIRTTFGLLIALTVLSNLIIISFVLIWFFTDGFGQLRLLFFTLFIPFFISLLVAIFLIFLNNSFRNFFQINEKNWLFLWTCVFSSLPIFNLWLIVRLNKTIKNFASDYGFKIVNKYNSLTSGIFVFDFADYVSFEANLTNWKNTNDKNRNFVNFFETISKEKTGVVQKPVLNFQRLYVNRLYYQSKLSVGSNQQTPQTAFDNLRNYVENKQRETVRVKQYILT
What are the official names of this protein?
Uncharacterized protein MG256.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YLMC_BACSU
Sequence: MISISEFQVKDVVNVSNGKKLGSIGDIDINVTTGKIQAIILGGNGKVLGFFGKEEELVIPWRNIVKIGEDVILVRLSEPHA
What are the official names of this protein?
Probable sporulation protein YlmC.
What is the protein family that this protein belongs to?
Belongs to the YlmC/YmxH family.
Protein: PUR5_BIFLD
Sequence: MPKAYENAGVSVEAGYEVVKRIKSHVARTNRPGVVGGIGGFGGLFDLASLGYKEPVLISGTDGVGTKLMVAKLANKHDTIGIDCVAMCVNDIAAQGAEPLFFLDYIACGKNDPALLEQVVAGVADGCVQAGSALVGGETAEMPGMYDEDEYDLAGFSVGVAEKSAIVDGSTIAEGDVLIGLPSTGVHSNGFSLVRKALFEQAGYTVDTELDELGGEKLGDVLLTPTKIYVKALSPLFKAGVVKGVAHITGGGFIENIPRMIPDGLAAEIELGTWPVLPIFDVLEKAGNIDHKEMYNIFNMGIGMVLAIDPARKDEALKLLADNNEPAYVLGSITADTTGTQIVLK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS181_RHOJR
Sequence: MPKPPLRDKVMKKKICIFCKEKNTQINYKDTTLLRKYVSDRGKIRARRVTGNCVQHQRDVAIAVKNSREVALLPYATVAR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.