PharMolix/UniProtQA huggingface dataset:
Protein: DF151_ARATH
Sequence: MKKPSQLSATILTIFVILAIGVMVKETLGQAPSTCFEALKDASKGASCDSELCASLCKKKSGGGVGTCRTKTTQPSKGQPECHCRFWCKSDGTPYK
What are the official names of this protein?
Defensin-like protein 151, Low-molecular-weight cysteine-rich protein 17, Protein LCR17.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPA4_CAEBR
Sequence: MGCVHSTGSEAKKRSQLIDAQLRLEHDQCGTEVKLLLLGAGESGKSTIVRQMRILHVIGFSKQEKLAYRAVIYSNMIQSMLVIIRVMKALGIDFENSAHKEDAHQFSSHYLHIHNADLSEAFSLELSDLMKNLWSDAGVRRCFKRSREFQLNDSTEYYFNSLDRISETTYLPTQDDILRARVKSTGIVETDFMYKDIYFRMFDVGGQRSERKKWIHCFEGVTAVIFCVALSEYDMKLAEDKIMNRMHESMQLFDSIVNNRWFTETSMILFLNKMDIFEEKIRHIPLNICFPEYKGGTSVTETSNYIRSVFEKLNKRKSTAQKEVYSHFTCATDTNNIRFVFDAVTDIIIRYNLKDCGLF
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-4 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
Protein: RL27_VARPS
Sequence: MAQKKGGGSTRNGRDSKPKMLGVKAFGGELISAGSIIVRQRGTQFHPGVNVGVGKDHTLFALVDGHVSFGVKGALNKHMVNVTPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: NDBQ_LYCMC
Sequence: MASKTVLVLLLVSVLVSTFCTAKAYPASLEDNFDLDALDDLDDLDLEDFYDLEPADLVLLDMWASMLENSDFEDDFE
What are the official names of this protein?
Anionic peptide 17.1.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SNX20_MOUSE
Sequence: MASPEHPGSPGWRGPINQCRTRTRQEVLPPGPDLPCPGPEEAQDGPSSNSSMTTRELQEHWQKEKSRWKHVRLLFEIASARIEERKVSKFVMYQVVVIQTGSFDSDKAVVERRYSDFERLQKALLKRFGPELEDVTFPRKRLTGNLSAETICERRRELREYLRLLYAVRAVRRSREFLDFLTRPELREAFGCLRAGQYARALELLGRALPLQEKLTAHCPSAAVPALCAALVCLRDLERPAEAFAVGERALRCLRTRENHRYYAPLLDAMVRLAYALGKDFAALQSRLDENQLRRPTHRDATLKELTVREYLS
What is the function of this protein?
May play a role in cellular vesicle trafficking (PubMed:25882846).  Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, nor on SELPLG-mediated cell-cell adhesion (PubMed:18196517).
What are the official names of this protein?
Sorting nexin-20.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane. Cytoplasm. Nucleus.
Protein: GPD2_CANAL
Sequence: MTTSPYPIETPFKVCIVGSGNWGTAVAKLVAENCAEKPNIFQRDVKMWVFEEEIEGRKLTEIINTEHENVKYLPEIKLPTNLVANPDIVDTVQDADLIVFNIPHQFLGRIVKQIEGKVKPTARAISCLKGLDVSPEGCKLLSTSITDTLKIYCGVLSGANIANEVAKGNWSETSIAYTVPEDFRGAGKDIDPFILKEAFHRPYFHVRVIEDVVGASIAGALKNVIACSVGFVEGAGWGDNAKAAIMRIGIKETIRFASYWELFKIKALSPPNPKTFTEESAGVADLITTCSGGRNVKVARYMIKNNVDAFEAEKIVLKGQSSQGILTAKEVHELLTNFNLQDEFPLLEATYKVIYENGSVDDFPQLLEGDQ
What is the function of this protein?
May catalyze the production and accumulation of glycerol during hyperosmotic stress conditions (By similarity).  Glycerol acts as a osmoregulator that prevents loss of water and turgor of the cells (By similarity).  Mediates evasion of the host innate immune system by binding inhibitory components of the host alternative complement system, in a manner dependent on estrogen-induced inhibition of EBP1 (PubMed:34986357, PubMed:23204165).
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)] 2.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted. Cytoplasm. Peroxisome. Note=Localizes to the cell wall in both yeast and hyphae.
Protein: LTUA_CHLMU
Sequence: MFFIRARFIGFLDVHGYLAAKKGQQVMRSGSSMWVGSQGPIFYKVF
What are the official names of this protein?
Late transcription unit A protein.
Protein: FEOC_SALTI
Sequence: MASLIQVRDLLALRGRMEATQISHTLHAPQPMIDAMLNQLEIMGKAVRIPEEPDGCLSGSCKSCPEGKACLREWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: ADAM9_HUMAN
Sequence: MGSGARFPSGTLRVRWLLLLGLVGPVLGAARPGFQQTSHLSSYEIITPWRLTRERREAPRPYSKQVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDHPNIQNHCHYRGYVEGVHNSSIALSDCFGLRGLLHLENASYGIEPLQNSSHFEHIIYRMDDVYKEPLKCGVSNKDIEKETAKDEEEEPPSMTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMILLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRHDSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDGRDCSCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNKLVDAGEECDCGTPKECELDPCCEGSTCKLKSFAECAYGDCCKDCRFLPGGTLCRGKTSECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKDCFIEVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQEIPVFGIVPAIIQTPSRGTKCWGVDFQLGSDVPDPGMVNEGTKCGAGKICRNFQCVDASVLNYDCDVQKKCHGHGVCNSNKNCHCENGWAPPNCETKGYGGSVDSGPTYNEMNTALRDGLLVFFFLIVPLIVCAIFIFIKRDQLWRSYFRKKRSQTYESDGKNQANPSRQPGSVPRHVSPVTPPREVPIYANRFAVPTYAAKQPQQFPSRPPPPQPKVSSQGNLIPARPAPAPPLYSSLT
What is the function of this protein?
May act as alpha-secretase for amyloid precursor protein (APP).
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 9, ADAM 9, Cellular disintegrin-related protein, Meltrin-gamma, Metalloprotease/disintegrin/cysteine-rich protein 9, Myeloma cell metalloproteinase.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: UBIG_PARXL
Sequence: MTNADPHELQKFSDLAHRWWDPNAEFKPLHELNPIRLSWIDAHAHLTGKTVLDIGCGGGILSESMASLGAHVKGIDLSTQALGVADLHSLESGVTVDYEEIAAEALAAREPGTYDVVTCMEMLEHVPQPAAIVEACRTLVKPGGWVFFSTLNRNVKSYLFAVIGAEYIAQMLPKGTHDYARFIRPSELASFARATNLRTADIKGIVYNPLSKHFTLSADTSVNYMLACRRDA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: KTHY_SALPC
Sequence: MGSNYIVIEGLEGAGKTTARDVVVETLEQLGIRNMIFTREPGGTQLAEKLRSLVLDIRSVGDEVITDKAEVLMFYAARVQLVETVIKPALAQGIWVIGDRHDLSTQAYQGGGRGIDQTMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGDLDRIEQESFDFFNRTRARYLELAAQDSRIRTIDATQPLDAVMRDIRATVTKWVQEQAA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: GSH1_PSET1
Sequence: MATHDLTNALDALSVTQHKHAINGIKRGIERESLRIKSDGVISAQKHPEGVGSALTNGQITTDFSESLLEFITPVSESSTQTLQQLKDLQKFTLEKMGDELLWPISMPCFIEHQDDIVIAQFGSSNVGQMKTLYREGLKNRYGSMMQAIAGVHFNISFPDSLWQSLHTLKNSDLSLEDFISDGYLALIRNFKRELWLISYLFGASPALCSSFLQGRKTDLPFKKLGKGTLYLEVGTALRLGNLGYTNSAQSSLRVMYNSLDEYVAGLKKSINTPSDIYGNLDDYTSENPKQLNKNILQIENEFYSPIRPKRNAKNGETPTDALLRAGIEYVEIRALDVNPFSEVGIDIEQFHFLDVFLTYCLLKSSPAMDWEEQTRSTENLDTVVNKGREKGLELNYFNQPRTLQSWGEDIFSQLSEVAKYMDTAYGVSYYSSTIERMATWINNPGLTYSGRYVAELEASGLDNGHYALAIAEKYKQSHQAADYQVFSKQWLEEQVTRSNDAQRAIEQSDSVSFTAFLNAYFDPK
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: G3PC_PEA
Sequence: MGAKIKIGINGFGRIGRLVARVALKRDDVELVAVNDPFITTDYMTYMFKYDSVHGQWKNDELTVKDSNTLLFGQKPVTVFAHRNPEEIPWASTGADIIVESTGVFTDKDKAAAHLKGGAKKVIISAPSKDAPMFVVGVNENEYKPEFDIISNASCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSSKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDVSVVDLTVRLEKAATYDEIKAAIKEESEGKLKGILGYTEDDVVSTDFIGDTRSSIFDAKAGIALNDKFVKLVSWYDNELGYSTRVVDLIVHIAKQL
What is the function of this protein?
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.  Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFA2_XENTR
Sequence: MWNNHGGFDGGYGGSGMGGGGYMQSPGGFGSPAPTQGEKKSRSRSQQIVPCTVSQLLSATQNDEMFRIGEAELSQVTIVGIVRHAEKAPTNILYKVDDMTAAPMDVRQWVDTDEASCENMVVPPGSYVKVAGHLRSFQNKKSVVAFKIAPVDDMNEFVSHMLEVVHAHMTMNSQGAPSGGGSAVALNTPGRLGDSGGAFSGGNDNATNGLTPHQSQILNLIKSFKGNEGMAFEELKNRLHGMNVNTIRQAVDFLSNEGHIYSTVDDEHYKSTDGD
What is the function of this protein?
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
What are the official names of this protein?
Replication protein A 32 kDa subunit, RP-A p32, Replication factor A protein 2, RF-A protein 2, Replication protein A 34 kDa subunit, RP-A p34.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Note=Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner.
Protein: KN13A_ORYSJ
Sequence: MGDSGDAVMARWLQSAGLQHLAASSTSSSSASTAGGGVDPRGGGGVGVGALGGGAGGGSLLPSLLMQGYGPQSIEEKQRLYMLLRSLNFNGETAPPSISEPYTPTAQSFGGGNSLEGFYSPELRGELGAGLLDLHAMDDTELLSEDVASEPFEPSPFIPKEMDEDDDDMLPGSQPGPSDNYNAVANEKESTARENNVAKIKVVVRKRPLNRKEVSRKEEDIITVHDSSSLTVYEPKLKVDLTAYVEKHEFCFDAVLDEQVSNDEVYRETVEPIIPIIFQRTKATCFAYGQTGSGKTYTMQPLPLRAAQDMVRLLHQPVYRNQNFKLWLSYFEIYGGKLFDLLSDRRQLLMREDGKKQVCIVGLQEFEVSDVQIVKEYIERGNAARSTGSTGANEESSRSHAILQLAIKKHIIVTDTRRQRDRDANESKNTKAVGKISFIDLAGSERGADTTDNDRQTRIEGAEINKSLLALKECIRALDNDQIHIPFRGSKLTEVLRDSFVGNSRTVMISCISPNAGSCEHTLNTLRYADRVKSLSKGSNTRKEQPTGPTIPSSKDSSSAPSYPMPIETEEIANQIQEKRPVETSRKAAENFTSNSSMEPDRNPVSMIPSYSNRGKEENGSSGLNDRERVDLNSSRISYNSKPQSVQSSANLQEEEKVTKVSPPRRKAYRDDKPERQSNYAKKDSGPETSRPGYKVQQAKQLQQQQRPTSASASQNSSRQSEKESSCDDVEIDAILEEEEALIAAHRKEIENTMEIVREEMNLLAEVDQPGSLIDNYVTQLSFLLSRKAAGLVSLQARLARFQHRLKEQEILSRKKSSR
What are the official names of this protein?
Kinesin-like protein KIN-13A, Protein SMALL AND ROUND SEED 3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-13 subfamily.
What are the subcellular locations of this protein?
Microsome.
Protein: UBE3B_XENTR
Sequence: MFGATQVSKAQFLDKARQAREERKGLKERDRAAIKIQALIRRFLCRCRLQKEIRQEVDDFLEGTEKGSVKANALSIFRISRKLLIIFQISQDRMRFEKLCRCILNSMENDNEPKVWFVSLALSKDLTLLWIKQIKDILWYCSEYLKQLKPDILQDSKLITVYLTMLVTFTDTLTWKILKGKGESLRPAMNHICANIMGYLNQKGFYSVLQILLTNGLARSRPSLSKGTLTALFSLALRPVVAAQYSDNLLRSFLIHIMSVPALVSHLSTLTPDRLSVIESNGLFHKFILFLSREDQCSDVCECLEGSHTLCLLGNLIHLGHLTEKVLEEEMFHFVSVLTQMLSYCQKYVSQKKSNLTHWHPVLGWFSQTVDYGLNESMPLLTKQLQHLWGVHMIRNLFREVLSKKLAENQDVSVPVSQSSSSSPQNNLPMKNLFKRAFQKSASVRHILKPIGGKKVDSPEVQKVCNICVLYQMALTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPQGGLKLFLECLSSDTEESRRLLAMLVLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGLLENAKGETLELFHSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPTLLFQELDKERKRAQLLLQYIPHVIPHKNRVLLFRNIVTKEKEKLGLVETNTASPHVTHITIRRSRMLEDGYDQLRQLSQNAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSSGDRLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSIFYSSVDELPSLDSEFYKNLTSIKRYDGDISDLGLTLSYDEDVMGQLVCHELVPGGKSIPVTNENKISYIHLMAHFRMHTQIKNQTVAFISGFRSIIRPEWIRMFSAPELQRLISGDNAEIDLDDLKKHTVYYGGFHGSHRVIIWLWDILANDFSSEEKAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSKKGILREKLRYAISMNTGFELS
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
What are the official names of this protein?
Ubiquitin-protein ligase E3B, HECT-type ubiquitin transferase E3B.
Protein: VE5_HPV31
Sequence: MIELNISTVSIVLCFLLCFCVLLFVCLVIRPLVLSVSVYATLLLLIVILWVIATSPLRCFCIYVVFIYIPLFVIHTHASFLSQQ
What are the official names of this protein?
Probable protein E5.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E5 protein family.
Protein: PUR3_BACSU
Sequence: MKKFAVFASGNGSNFEAIVTRLKEENWDASAALLVCDKPQAKVIERAEAFHIPSFAFEPKSYENKAAFEQAIIEQLRLHEVELIALAGYMRLIGDTLLQAYGGKIINIHPSLLPAFPGIDAVGQAFRAGVKVAGITVHYVDEGMDTGPIIAQKAIEIDEHDTLETIEQRIHKLEHKWYPSVIKQLLGLNNRGEKA
What is the function of this protein?
Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
What are the official names of this protein?
Phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase, GAR transformylase, GART.
What is the protein family that this protein belongs to?
Belongs to the GART family.
Protein: RS5_TRIL1
Sequence: MSRINANDLNLTDRVVHISRVAKVVKGGRRFSFSALVVVGDASGHVGYGLGKANEVPEAIRKGVEQAKKNLIKVPVNQNQSIPYEIIGRFGAGRILMKPASPGTGVIAGGAARAIFEAAGISNILSKCLGSNNPHNVVKAAFEGLRLLKTPEELTARRGLAE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RL1_FRATM
Sequence: MAKVSKRMKEISAKINAEKKYPVSEAFDLLREVSSVKFVESVDVSVALGVDPRKSDQVVRGASVLPNGTGKTVRVAVFAKGPAADAAKEAGAEVVGMEDLADEVKKGNMDFDVVIASPDSMRVVGQLGQILGPKGLMPNPKVGTVTMDVAKAVRDAKAGQVRYRVDKAGIIHTTIGKVNFTSDALKQNLEQLLTDLKKAKPAVSKGIYLKKVSVSSTMGPGINVDFSDLNI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CAIC_SALA4
Sequence: MDIVGGQNLRQMWDDLAGVYGDKTALIFESCEGIVRQFSYASLNEEINRTANLFYSLGIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESAWILQNSQVSLLVTSAQFYPMYREIRQDNSTPLNHICLIGEQLPADDGVSHFTQLQSRQSTTLCYTPALSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQIALRDDDVYMTVMPAFHIDCQCTAAMPAFSAGSTFVLLEKYSARAFWDQVRKYQATVTECIPMMIRTLMVQPAAPTDRQHHLREVMFYLNLSEQEKDDFTERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATARALEPEGWLHTGDSGYQDEDGYFYFVDRRCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIKDAIRDEAIKAFIVLNEGETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCSGKIIKKNLK
What is the function of this protein?
Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle.  Also has activity toward crotonobetaine and gamma-butyrobetaine.
What are the official names of this protein?
Crotonobetaine/carnitine--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: MED16_DROME
Sequence: MTILYKVEGKEFSKDSVFPHKKVLCSVSARNIVAFSALQSAIFPASHGGDAGDGSLPGAGLAVGASNSHVYVCDIVTPWEYYKVCSSKSLISVLQWSPNGEQLLLGYVGGRVEIWQPRNQSINLWVLQYYATVPSEDIIEAQFFQNGKGVIFNALKKDHTYYAEKFERVEQQRPTLSGFGGVASEGCVLLTSSGLLAAFSLPAIQKTSAAGADGPAHEVVELTPALHSIGISRSFIEHCSMTPSPSGALNIAFSCGWQQQLVQCFKVSLSLEGELGLEQHLAIKSESQTSIFLGPLDGRRISHLKWTRIANEDVIFIAYACPDGAGSQLEQWTLTRRHQSVHALLQGGGGANNKPNEFVQSESWEQVGKVQLNASLADISVTRLSVSTPDSCQVYAILQDNSVQVLEPNSMKQLNHTQFDRLSDASGAVKFVSGDLTPSSQILLIFDSHAQLYAMQAPLPKQGGSGLLLLEYCIVTGCDASDVLLLNLGNLEALVEKLTDNFTRQPSFVRHFYYANFLALKSNICRMQQQEFDNLIILHAISTTFKSLLRPSDLGFQDKGPADNLAIKLAESIPDVDTVMLNLDAKDFTVEPVMLQSLQQLIQWVTDLALNMLHRLPEEVMKTKLSGKRPSYDISRDIVAISSLRELLVMIRIWGLLNTQCLPVYTKTMDNIDVLVILFRLLTRLAQNPAEPDEMLLDECSLLSKQLLIPQPTKFNPTTLLSAQGFAAVKSGQLQFTSMEEPTCLQDMETEEVVFASSVKDGVSNLQLGARPSHIRRCARCGFVFVNNASKVAKTSALKAWFSKWLHCHCGGFWKQVH
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).  Required for activated transcription of the MtnA, MtnB and MtnD genes.  Required for transcriptional activation in response to lipopolysacchardie (LPS).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 16, Mediator complex subunit 16.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURL_RHOPA
Sequence: MSAPEPKITPELIASHGLKPDEYQRILDLIGREPTFTELGIFSAMWNEHCSYKSSRIHLKGLPTKAPWVLQGPGENAGVIDIGDNQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTMGARPIACLNALSFGDPSHPKTRHLVSGVVAGVGGYGNSFGVPTVGGQTRFHTRYDGNILVNAMAVGLADADKIFLAAASGVGMPIVYLGSKTGRDGMGGATMASAEFDEGSDEKRPTVQVGDPFAEKLLLEACLEIMAKDCVIAIQDMGAAGLTCSAVEMGAKGDLGVELDLDAVPTRETGMTAYEMMLSESQERMLMVLKPEKEKEAEEIFKKWGLDFAIVGYTTPTKRFVVKHGGQVKADLPIKELGDEAPLYDRPWVESERLPVIHARDINAPMGAAEALEKLLATPDLCSKRWVWEQYDHVIGGNTVQRPGGDAAVVRIEDGPKGLALTVDVTPRYCEADPFEGGKQAVAEAYRNITAVGGKPLAITDNLNFGNPERPEIMGQLVGCLKGISEACIALDSPIVSGNVSLYNETSGRGILPTPSIGGVGVLDDFTKSATLAFKAEGEAILLIGETKGWLGQSVYLREICGREEGAPPPVDLAVEKRHGDVVRGMIHAGTATAVHDVSDGGLLVAIAEMAIAGNIGASLDAPPGETVSHAWWFGEDQARYVVTVKEADLLAVKTKLKTIGVPCTQIGVTGGHALKIEGERTVDLKALRHAHEHWLPDYMGGKN
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_ACIAC
Sequence: MAQKKGGGSTRNGRDSKPKMLGVKAFGGELISAGSIIVRQRGTKFHPGTNVGVGKDHTLFALVDGHVSFGTKGAMSKHTVSVTPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PROS_MOUSE
Sequence: MRVLSARFRVLLACLALVIPVSETNFLSKERASQVLVRKRRANTLFEETMKGNLERECIEELCNKEEAREVFENNPETDYFYPKYLGCLGAFRVGSFHAARQSANAYPDLRSCVKAISDQCDPIPCNEDGYLACQDGQAAFTCFCKPGWQGDRCQYDVNECKDPSNVNGGCSQICDNTPGSYHCSCKRGFAMLPNKKDCKDLDECALKPSVCGTAVCKNIPGDFECECPDGYRYDPSSKSCKDVDECSENMCAQLCVNFPGGYSCYCDGKKGFKLAQDQKSCEGIPVCLSLDLDKNYELLYLAEQFAGVVLYLKFRLPDITRFSAEFDFRTYDSEGIILYAESLDHSNWLLIALRDGKIEVQFKNEFSTQITTGGNVINNGIWNMVSVEELDDSVSIKIAKEAVMNINKLGSLFKPTDGFLDTKIYFAGLPRKVESALIKPINPRLDGCIRGWNLMKQGALGAKEIIEGKQNKHCFLNVEKGSYYPGSGIAQFSIDYNNVTNAEGWQMNVTLNIRPSTGTGVMLALVSGGTVPFALSLVDSRSGTSQDIVVFVENSVVARLEAVSLCSDQQSQLKCNVNRNGLELWTPLRKDVIYSKDLQRQLAVLDKAMKRTVATYLGGIPDISFSATPVNAFYSGCMEVNINGVQLDLDEAISKHKDIRAHSCPSVRKIQKNF
What is the function of this protein?
Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa.  It helps to prevent coagulation and stimulating fibrinolysis.
What are the official names of this protein?
Vitamin K-dependent protein S.
What are the subcellular locations of this protein?
Secreted.
Protein: RPIA_PSESM
Sequence: MTQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAKHKGAFDGAVASSEATAARLKGHGIPVYELNTVSDLEFYVDGADESDEHLNLIKGGGAALTREKIVAAVAKTFICIADGSKLVPVLGAFPLPVEVVPMARSHVARQLVKLGGDPVYREGVLTDNGNIIIDVHNMSITNPVELEASINAIVGVVTNGLFAARPADLLLLGTAEGVKTLTR
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: HYCB_SHIFL
Sequence: MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEKESAPQLCHHCEDAPCAVVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGSRPLDIPANANTPKAPPAPPAPARVSTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCPTKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK
What is the function of this protein?
Probable electron transfer protein for hydrogenase 3.
What are the official names of this protein?
Formate hydrogenlyase subunit 2, FHL subunit 2, Hydrogenase-3 component B.
Protein: PYRF_PROM1
Sequence: MKNIDNPSEKIIIALDGMDKDDVVNLLKKIPEIVWVKVGLELFVSEGPDVLSMLREKGKKIFLDLKFHDIPTTVARACFAASQTGAEFISLHTCAGMKALKMANEAANEGASKVNLIPPKLLGITILTSWTRESFCNDLLINQSIDQRVKHLAEIASNSGLGGCVCSPKEVQFLRESYPETFELITPGIRSLGSNVNDQSRVSDASEAIKMGASKLVIGRAITQSNDSAYMFKSFCDKISI
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: SYS_PROM2
Sequence: MLDQKLIRENPTSVEENLSLRGKVYNISHIHELTVKKKDIDIKISSLQSESKKLSKLIGQEISKSKNNDSPELISLKKKGNEYRIKISELEEKQRILDKEVDDEIYNLPNFPSKNAPIGKDENDNIQVKTWGNPLKDENLKSHWEIGESLNIFDSVKSTKISKSRFVTLIGNGARLERALINFMLDMHTKNGYLELMPPALVNSESLKGSGQLPKFSNESFKCSNDDLWLSPTAEVPLTAFHRNELIDPKQLPIKYVAYSPCFRREAGSYGKDTKGLIRLHQFNKVELYWFCDPTKSLEAHKKITSDAENIFKKLNLPYRIVDICTGDLGFSSSRTFDLEVWLPSSKCYREISSCSNCLDFQARRSSIRSKIDKKNIYLHTLNGSGLAIGRTMAAILENGQQTDGSVKIPDALVPYFGSNFLKNA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXZD9_LYCSI
Sequence: MMKVLVVVALLLTLIIYSSSDGIDDLEADELVSLMAHEQTRAKACTPRYYDCSHDRHRCCRSSMFKDVCTCFYPEGGHYKEVCTCQQPKHLEYMEKAADKIKNLFG
What are the official names of this protein?
Toxin-like structure LSTX-D9.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 02 (D7) subfamily.
What are the subcellular locations of this protein?
Secreted.