PharMolix/UniProtQA huggingface dataset:
Protein: FTSB_GLAP5
Sequence: MRVLVVVLALLLGGFQYAFWFGQNGWNEYQQAKQEVSQLKETNQKLTARNQLIQAEIEDLKTGINALEERARLDREMVKPDETFYRIVPREQR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: CCN2_MOUSE
Sequence: MLASVAGPISLALVLLALCTRPAMGQDCSAQCQCAAEAAPHCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCVFGGSVYRSGESFQSSCKYQCTCLDGAVGCVPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDRTAVGPALAAYRLEDTFGPDPTMMRANCLVQTTEWSACSKTCGMGISTRVTNDNTFCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKIAKPVKFELSGCTSVKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEIMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
What is the function of this protein?
Major connective tissue mitoattractant secreted by vascular endothelial cells.  Promotes proliferation and differentiation of chondrocytes (By similarity).  Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity).  Enhances fibroblast growth factor-induced DNA synthesis (By similarity).
What are the official names of this protein?
CCN family member 2, Cellular communication network factor 2, Connective tissue growth factor, Hypertrophic chondrocyte-specific protein 24, Protein FISP-12.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: RUVB_VIBC1
Sequence: MIEADRLIAPENPSFREEDVIDRAIRPKKLADYQGQDHVRDQMEIFIKAAQLRNEALDHLLIFGPPGLGKTTLANIVANEMEVNIRTTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGITQRLEYYKVKDLQDIVQRSADCLGLSMESEGALEVARRARGTPRIANRLLRRVRDYAEVKGNGHICADTADKALNMLDVDAEGFDYMDRKLLLAIMEKFGGGPVGLDNMAAAIGEEKDTIEDVLEPYLIQQGYLQRTPRGRIATDRAYLHFGIEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: NU1C_CHAVU
Sequence: MSSLVRLKFNAIKLVIDFGISENIAYLISIFLPIVLLLVISVLGVLVTVWLERKISAAVQQRIGPEYAGSLGIMQAIVDGVKLLIKEDIIPAQGDRWLFSIGPVLVVTPVILSYLVVPFGKNIILSDIRLGIFFWIVISSITPLGLLIAGYASNNKYSLLGGLRAAAQSISYEIPLTLCVLSISLLSNTLSTSDIVEQQCKYGILSWNIWRQPVGFITFFIASLAECERLPFDLPEAEEELVAGYQTEYSGIKFGIFYVASYLNLLVSSLFAVVLYLGGWNFPIPTTLIFFISMYKVSLPLDSSNLLLELIIPIIHISITLAKTYLFIFFAILARWTLPRIRIDQLLDLGWKFLLPMAVGNLLLTASFQLTLFEFS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GLGS_SHIFL
Sequence: MEHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTWFCARYAWYCQQMMQARELELEH
What is the function of this protein?
Major determinant of cell surface composition.  Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
What are the official names of this protein?
Surface composition regulator.
What is the protein family that this protein belongs to?
Belongs to the GlgS family.
Protein: RASL1_MOUSE
Sequence: MAKSGSLSIRVVEGRALPAKDVSGSSDPYCLVKVDDQVVARTATIWRSLSPFWGEEYTVHLPLDFHHLAFYVLDEDTVGHDDIIGKISLSKEAITADPRGIDSWINLSRVDPDAEVQGEVCLDVKLLEDARGRCLRCHVRQARDLAPRDISGTSDPFARVFWGNHSLETSTIKKTRFPHWDEVLELREAPGTTSPLRVELWDWDMVGKNDFLGMVEFTPQTLQQKPPNGWFRLLPFPRAEDSGGSLGALRLKVRLTEDRVLPSQYYQPLMELLLESVQGPAEEDTTSPLALLEELASGDCRQDLATKLVKLFLGRGLAGPFLDYLTRREVARTNDPNTLFRSNSLASKSMEQFMKLVGMRYLHEVLRPVISRVFEEKKYMELDPCKMDLNRSRRISFKGTPTEEQVRETSLGLLTGYLGSVVDAIVSSTGRCPLALRLAFKQLQRCVEKRFSGIEHQDVKYLAISGFLFLRFFAPAILTPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKEQWLAPLHPFLLQSISRVRDFLDQLVDVDEDEEAGGPACALVQPSTIVREGFLLKRKEEPGGLATRFAFKKRYFRLSGRDLSYSKTPEWQVHTSIPLSCIRAVEHVDEGAFQLPHVMQVVTQDGAGTSHTTYLQCKNVNDLNQWLSALRKASAPNPGKLVACHPGAFRSGRWTCCLQAERSAAGCSRTHSAITLGDWSDPLDPDAEAQAVYRQLLLGRDQLRLKLLEDSSLDTEVDPGRDSSATDGPCAEVLAQQRAATTHLLQVLEDLEQAHEEFQKRG
What is the function of this protein?
Probable inhibitory regulator of the Ras-cyclic AMP pathway.  Plays a role in dendrite formation by melanocytes.
What are the official names of this protein?
RasGAP-activating-like protein 1, RAS protein activator like 1, Ras GTPase-activating-like protein.
Protein: SYM_ACIF5
Sequence: MKRRILITSALPYANGPIHLGHLVEYTQTDIWARYQRLRGHDCVYVCADDAHGTPIMLRAQSEGITPEELITRMHGDHLRDFTGFGIRFDLYHSTHSPENFEISQSIYRALRAADYINVREIEQAYDPVAGIFLPDRFIRGTCPRCGAADQYGDSCEVCGATYSPTDLINPVSAVSGAVPERRNSEHYFFQLGDFSDFLRRWIHSGTLQEEVAHKLDEWFSIGLSDWDISRDAPYFGIPIPDAPGKFFYVWLDALPGYMAATQHWCAAHGRNLADYWGPDSAAEIYHFIGKDIIYFHGLFWPAMLKGSGHRLPTGIFAHGHLTVNGAKMSKSRGTSITARQYLQHLNPEFLRYYIATKLNSHVEDIDLNLEDFLLRGNGDLVGKVVNLASRAAGFIHRSFAGRLAASLGKDQAFYDGLLQTQEAIGEAYAGREYGKAMRDIMALADQINAYVDQNAPWTLAKDPAQHESLHRVVTVTLNGFRVLITLLSPVLPELSRKALEFLQCELDWAGLSKPLLDHQILPYSHLLQRMEKTQVDALIQNPAESPATAPGTAAAPVPTPVPAEAREENPFIGIDDFSKVDLRIARIVAATNVDGADKLLHLTLDIGEGTRSVFAGIKSAYDPASLVGRLTVMVANLAPRKMRFGLSEGMVLAASGPEGGPFLLSPDSGAQPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_DICNV
Sequence: MARETSINKYRNLGIMAHIDAGKTTTTERILFYTGVSHKLGEVHEGAATMDWMEQEQERGITITSAATTCFWQGMAGQFDKHRINIIDTPGHVDFTIEVERSLRVLDGACLVLCSVGGVQPQTETVWRQANKYKVPRIAYVNKMDRTGANFLRVVKQMHDRLKANAVPLQLPVGAEDTFKGVVDLIKMKEIIWDEETNGLKFEYGDIPEEMRAQAEEYREKLVEAAAESSEELMDKYLESGTLSEEEIIAGLRQRTIANEIIPVLCGSSFKNKGVQAMLDKVIELLPSPVDVPAIQGVNPNTNETEKRESTDDAPFSALAFKIATDPFVGTLTFVRCYSGVLEAGTTVLNSVKDKKERIGRIVQMHSNSRVEIKEVHAGDIAACIGLKEVVTGETLCDVNAPIILERMEFPEPVIAVAVEPKTKADQEKMGLALAKLAQEDPSFRVHTDEETGQTIISGMGELHLEIIVDRMKREFKVEANVGAPQVAYRETIRESVEQEGKFVRQSGGRGQFGHVWLRIEPQEPGFGYEFVNQIVGGVVPKEYIPAVDKGVQEQMQNGVLAGYPVVDIKVTLYDGSYHEVDSSEMAFKLAAAEGFKLGARKAKPVLLEPMMKVEVSTPEEYMGDVIGDLNSRRGLIQGMDDELTGKVIHAQVPLANMFGYATSLRSLTQGRANYSMEFDCYNEAPNNVVEEVIKSKSK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_SALPA
Sequence: MFDVLMYLFETYIHNEAELRVDQDRLERDLTDAGFDREDIYNALLWLEKLADYQDGLAEPMQLASDPLSMRIYTVEECERLDASCRGFLLFLEQIQVLNLETREMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: RCF1_CHAGB
Sequence: MSDRPTQGLTWGPRRDFYNESGSQKIIRKLKEEPLVPIGCILTIAAFTNAYRAMRRGDHHKVQRMFRARVAAQGFTVLAMVGGGMYYAEDRNKRKELGKLKQQQEAEEKRQKWIRELEARDEEEKALQEMMDKKRKRASERTMRAETGSEGIAAQARAAFKDKANKGEAAGAEKTEAPSQRADNEKKPAGSGFLGGWFGGSSKTPETPAKDTKGKNLDSESSS
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RL31_STRAW
Sequence: MKRDIHPEYVETQVSCTCGASFTTRSTISSGTVRAEVCSECHPFYTGKQKILDTGGRVARFEARFGKAAAAKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: SYA_BURA4
Sequence: MKAAEIREKFLKFFESKGHTIVRSSSLVPGNDPTLMFTNSGMVQFKDVFLGTDPRPYSRATTAQRSVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIRFAWELLTTVYQLPKEKLWVTVYQEDDEAYDIWAKEVGVPTERIIRIGDNKGARYASDNFWTMGDTGPCGPCTEIFYDHGPEVWGGPPGSPEEDGDRYIEIWNLVFMQFNRDAQGNMTRLPKQSVDTGMGLERLAAVLQHVHSNYEIDLFQNLIKAAARVTEISDLTNNSLKVIADHIRACSFLIVDGVIPGNEGRGYVLRRIVRRAIRHGYKLGRKGSFFHKLVADLVAEMGAAYPELKEAEQRVTDVLRQEEERFFETIEHGMSILEAALADVEAKGGKVLDGELAFKLHDTYGFPLDLTADVCRERGMTVDEPAFDDAMARQREQARAAGKFKATQGLEYTGAKTTFHGYEEIAFDDAKVVALYVDGSAVNEVKAGQDAVVVLDHTPFYAESGGQVGDQGVLANAATRFAVADTLKVQADVVGHHGTLEQGTLKLGDVLRAEIDAHRRARTQRNHSATHLMHKALREVLGAHVQQKGSLVDAEKTRFDFAHNAPMTDDEIRRVEQIVNNEILANAPGIVRVMPYDEAVKGGAMALFGEKYGDEVRVLDLGFSRELCGGTHVHRTGDIGFFKIVVEGGVAAGIRRVEAITGDNAVRYVQELDARVNEAAAALKAQPSELTQRIAQVQDQVKSLEKELGALKSKLASSQGDELAQQATEVGGVYVLAATLDGADAKTLRETVDKLKDKLKSAAIVLAAVEGGKVSLIAGVTPDASKKVKAGELVNFVAQQVGGKGGGRPDMAQAGGTDPANLPGALAGVKGWVEERL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_CHRSD
Sequence: MKIRPLHDRVVVRRVEEEQKTAGGIVLPGNAQEKPTRGEVLAVGNGRILESGEVRPLDVKVGDTVIFKDGFGVEKQKIDGEEVLIMSESDILAVAE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_ANADF
Sequence: MGRERVTVVGGGLAGSEAAWRLAQGGVEVELVEMKPGRRSPAHVLDGLAELVCSNSLRSDNPHNAVGLLHEELRRLGSLVLSAADATRVPAGDALAVDRERFSALVTGRLRGHPLVRVRQEELLRLPEGPGLTLVATGPLTGDALAADVAALAGGRLHFYDAIAPIVAADSIDMSIAYARSRYGKGSGDDYLNLPFDEGQYRAFVGALLAGEKVAAHDFEEPRYFEGCLPIEVMAERGADVLAYGPMKPVGLEDPRTGRRPFAVVQLRREDVAGTAYNLVGFQTRLTWTEQRRILREYVPGLAGAEFVRLGQIHRNTFLEAPRVLAPDLSARERPHLFFAGQITGVEGYVESAACGHLAARAMLDRLAGRPFLPPPAATALGALHRHLTGEAHPPGYDYQPTNVVFALFPPLTGRHRGKAARKDAHAERARKEIAPWIDPWTHTARGAAAP
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y465_TREPA
Sequence: MSQVLTVLHALSSPPWICLLSFNRMVLARQCAFVLVSCVVPCVAGAVLSSCMPFYARTEGLTLKRVYFEKAGKTDATLALHVTLEYPAPPEEYFYLEVEELRTGMRWVFGEKDTRVYIATDELHPGRRMLRVGGMQYPWGDFPAGTYVVYVRDSTGTYAQQRVTLGAGYPAHEPFPFSFSVDAQRWTLSAPAQPALVGPFTAHTHTSLVLLTRDYRTVAQHPLSLTSLPNARLSSPRVHTFEASMDALKTTHQDAYYLQCVVEDFQRSWRFISQPHRLYPEDALSEQAPP
What are the official names of this protein?
Uncharacterized protein TP_0465.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TGT_OLEA2
Sequence: MATIGEFTLHATDGKARTGVLQTAHGPVRTPIFMPVGTVGSVKGVAPDDLDAIGAEIILGNTYHLYLRPGDELVARRGGLHEFNAWRKPILTDSGGFQVFSLSGLRRISEEGVEFRSHLDGSKHLFTPEKVVSIQRNLNSDIMMVLDECVPYGADKDYTARSLKMTTRWAQRCRDAYPAGSGGNLMFGITQGGFFKDLREESIGELTRIDFDGFALGGLSVGESKTEMMDILYHTAPMLPAHKPRYLMGVGTPLDIINGINAGIDMFDCVLPTRNARNGTLYTSAGKINIKRREFAEDDGPLDPNCSCYTCRTFSRAYLRHLFHAQEILSYRLNSIHNLTYFLDLVRGAREAIAQGTFAEYKSRYDAIYPQEAALCP
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TRUC_ECO57
Sequence: MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIGQHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDYPLVEELDKIADKFAREDKGPQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGRKHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLTIHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGERSS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase C, tRNA pseudouridine(65) synthase, tRNA pseudouridylate synthase C, tRNA-uridine isomerase C.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: RK23_PIPCE
Sequence: MDGIKYIVFTEKSIRLLGNNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLQGKGRRMGPIIGHTMHYRRMIITLQPGYSIPPLIEKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS15_PSEPU
Sequence: MALSVEEKAQIVAEYQQTAGDTGSPEVQVALLTANINKLQGHLKPTTKTTTPVRGLIRMVNHRRKLLDYLKGKDTTRYSALIGRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: Y2816_SERP5
Sequence: MSLTDGVLLIFTALMLVYAIYDEFGMNLLKGKTLLKVQLKRRNRIDCLIFVGLITILLYRNVTTQGAVITTYLLISLALIAIYISYIRWPKMLFKAQGFFYANAFIEYNRIKAMNLSEDGILVIDLEQRRLLIQVTQLDDLEKIYHFFVENQ
What are the official names of this protein?
UPF0266 membrane protein Spro_2816.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2077_ARCFU
Sequence: MKKLLIILAATLVLVLGSSGNFREYYGARGVAVNIADNNSSYIGFECPEMTLYLANGDSTGVISVKNNLGEDVELYFSTPNDILTFSNPTFLYAGEEKLVEAEFRGSQGEYTIPIDIEAFWDNGSAKIPACSVKVVDPAVRMSKVLLSGNTTVPLFTREVWKFRILVESDAGDNYTILDTIPAEFEVLSIAASDGSFATHHPGAGRSCTTKIVWDVYVEGTEFMDVTIATKHNPAGKQEFTSPGSYNLNDGAEIKGLGIVSNPIIVKAVR
What are the official names of this protein?
Uncharacterized protein AF_2077.
Protein: MVFR_PSEAE
Sequence: MPIHNLNHVNMFLQVIASGSISSAARILRKSHTAVSSAVSNLEIDLCVELVRRDGYKVEPTEQALRLIPYMRSLLNYQQLIGDIAFNLNKGPRNLRVLLDTAIPPSFCDTVSSVLLDDFNMVSLIRTSPADSLATIKQDNAEIDIAITIDEELKISRFNQCVLGYTKAFVVAHPQHPLCNASLHSIASLANYRQISLGSRSGQHSNLLRPVSDKVLFVENFDDMLRLVEAGVGWGIAPHYFVEERLRNGTLAVLSELYEPGGIDTKVYCYYNTALESERSFLRFLESARQRLRELGRQRFDDAPAWQPSIVETAQRRSGPKALAYRQRAAPE
What is the function of this protein?
Transcription regulator that plays a critical role in virulence by positively regulating the expression of multiple quorum sensing (QS)-regulated virulence factors, genes involved in protein secretion, translation, response to oxidative stress and the phnAB operon (PubMed:11724939, PubMed:27678057, PubMed:17083468).  At the stationary phase, negatively autoregulates its function through cleavage and translocation to the extracellular space (PubMed:11724939).
What are the official names of this protein?
Multiple virulence factor regulator MvfR, Transcriptional regulator MvfR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cell inner membrane. Secreted. Note=At stationary phase, gets cleaved and subsequently released in the extracellular space where its transcriptional activity is inhibited.
Protein: RL22_BIFLS
Sequence: MEAKAIARHVRVTPRKARRMVDLIRGKKATEAVTILKFAPQAAALPVRKTLESAIANARVKADKAGEPFRENDLYIKETYVDEGVTLKRFRARAQGRAARINKRTSHITVVVANKEGAR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RK2_EUGLO
Sequence: MVVRIYNPCTPGTRHRSVNDFSGVANSKYRKNLSFFLHRSKGRNNRGVITNRNLGGGHKRLFRKIEFKRDKFSIFGKVLSIEYDPNRSSRIALVIYSDGIKRYIIQPLNLVIGNKIISDFHTTIDIGNALPVNFIPLGTLVHNVEFKPGNGGKIARAAGAFSKIIAKDKNFVSLSMPSGETRLIENSCWATIGQVGNLDFYNVILGKAGRNRWLGNNPSVRGIAMNPCDHPHGGGEGRSPIGRSKPLTPWGKIALGKRTRKPKRYSNKYILSRK
What are the official names of this protein?
50S ribosomal protein L2, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid.
Protein: SYC2_TROWT
Sequence: MYTFEVFDSRTRSIVKLEDCLLRLYVCGITPYKSTHLGHAFTYVGFDTLFRLALDSGRDVLYIQNISDIDEPLFQYAEKVGIHYKDLARTQTKRFFEDMHTLECLPPGYVIPVSKVLDGIKTGIEGLISRNMAYKLPNGDVYFDSTLTDPGKMFCFDRKTAMSLMLETDTGKNPFDPLLWRGRGAEPQWEASFGAGRPAWHISCAVLSNLQTQYENVLHIYGGGRDLAFPHHEFTNVLSKLIRAPKDNKQQDTVQDVFMHTGLVSYMGDKMSKSKGNLVFISQLREQCEKIGLHHSVIRLALLQRHYREDWEWQDECLDRAASRFRLWKSALQEYIGAKGIRSTADQNKGTQGAWERIHGGVFDSNFDHRQPIHPKHSPQMRDYSEHGSAGQNGTDLDLSLYQAIRFHLCNDLDTPKALDAVDSYARKGTITIPEARAVEKLLGIPLTRV
What are the official names of this protein?
Putative cysteine--tRNA ligase 2, Cysteinyl-tRNA synthetase 2, CysRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPLL_SORBI
Sequence: MAKLHRLISAVLRLAAAGAAAAAAIIMVTSHETTSFFGIEMEAKYSYTPSFVFFVVAFAVAFAYSLLALLARPGSTASRLLLLSDVMVGMLLTGAVAATGAISQVGKSGNEHAGWLPICAQVQAYCSHVMGALIAGFVSLLLYFLIIMYSLHAVAEPLCSCH
What are the official names of this protein?
CASP-like protein 1C1, SbCASPL1C1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 3606L_ASFM2
Sequence: MNSLQVLTKKVLIENKAFSNYHEDDVFILQQLELWWENGPIGFCKQCKMVTSGSMSCSDVDSYELDRALVKAVKKNQTDLIKLFVLWGANINYGIICAKMERTKVLCIQLGADPTFLEVGLYTMFVDLFKQQKVLLAIDIYYENIPILDSFDSHDFYALINFIYNRYILYLDEKEEMTRNTLVLKFWFKIAIEFNLIKPIRFLSKKFPHLDDWRLKMAVYLGNVDEIHHAYFQENIRLDPNHMMSLACMYPQNKLGIYYCFALGANINTALETLIRFINHEVDREITFFSNYGIWSNVHFCISLGANPYIKKIQETLLREEKNVIMKLFFKKGLLTSHSILHKKILEPGEVRKIISTYEYTETFHSFSSLRDNLR
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-6L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: CSPE_SHIFL
Sequence: MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTLAEGQRVEFEITNGAKGPSAANVIAL
What are the official names of this protein?
Cold shock-like protein CspE, CSP-E.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_DICT6
Sequence: MSRIGKKPVPIPQNVQVEIKDGNCVLVKGPLGQLEKTFSPLLTIKKVDNQIVVERPNDEKFVKALHGLTRALINNMVLGVTQGFEKRLELQGTGYRARVQGNKLILEVGFSHPVELEIPTGLTVTVQDNTKISVKGIDKELVGQFAAIVRSVRPAEPYKGKGIRYEGEKIRQKAGKAGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RF1_SHEB2
Sequence: MKESVIRKLEGLLERNEEVMALLGDASVISDQDRFRALSKEYAQLEDVVAGFKAYQQAQVDLDSAKEMLEEDDAEMREMAQEEMKAAKAKLEHLEDELQILLLPKDPDDDKNAFVEIRAGAGGDEAAIFAGDLFRMYSRYAEANRWQIEIMSCNEGEHGGFKEVIMKVSGDGVYGKLKFESGGHRVQRVPETESQGRVHTSAVTVVVLHEVPEAEAISINPADLKVDTFRSSGAGGQHVNKTDSAIRITHIPTGIVVECQDQRSQHKNRAQAMSVLAARIQALEDEKRRSAEESTRRSLVASGDRSERVRTYNFPQGRVSEHRINLTLYRLNEVMEGDLDAILLPLMQEHQADQLAALADEQG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.