PharMolix/UniProtQA huggingface dataset:
Protein: SLX9_YEAS7
Sequence: MVAKKRNTLRSKASARNSQNFGPDVANNGILDESYDIESDPRAFLHQPKETKKEKLLNRQNTFLSNLKGKSTLSDGIGANFDGISKSSIRRRKRKLREELKPRMQDLLTSLEQEKDLRGIIENSSKDMNNDDDIDMDSKIRFVDTKEMNLKKIEPGSVRIKKNQPNIRNQKGAKALAANETARFNQVLTNQDFQKNPFGALREVIKLQKH
What is the function of this protein?
Involved in ribosome biogenesis.  Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1).  May be involved in the movements of the replication forks (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein SLX9.
What is the protein family that this protein belongs to?
Belongs to the SLX9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYGA_LIGS1
Sequence: MTKKLALQDIILTLQQFWAKQGCMLMQSYDTEKGAGTMSPYTFLRAIGPEPWNVAYVEPSRRPADGRYGDNPNRLYQHHQFQVLMKPSPSNIQELYLDSLRALGIEPKEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLEVKPVAAEVTYGLERLSSYIQDVDSVYDLEWADGVKYGDIFKEPEYEHSKYSFEESNQEMLLNLFDTFETEAKKQLANGLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMAKSVAKVFVAERKKLGYPLIKDEKLRQELLKEEK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_CLOP1
Sequence: MELENQLSKLHELKNNLKEMGASLCLASLEKKSAELELKMQEAGFWDDVQKAQEVTQEAKRVKDKIDKFKNLNERIDDVEVLKELMEENDEETAKEIISEVKALSKEIDTLKIETILSGEYDRNDAILTLHTGVGGSDANDWTEMLLRMYTRWCEKKGYSLETIDYLPGDEAGVKSVTLKVKGEFAYGYLKAEKGIHRLVRISPFNANGKRQTSFASVEVLPELTSDQDIEINPVDLRIDTYRAGGAGGQHVNKTESAVRITHIPTGIVVQCQNERSQFSNRDTAMGMLKSKLIELKERAHKEKIEDLTGELKDMGWGSQIRSYVFHPYSMVKDHRTNVETSNVNGVMDGDIDNFIIAYLNS
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_RHOP2
Sequence: MTSRDSAAAEITPEVLLRAYACGIFPMAESVDDPTLFWVEPELRGIIPLGGFRVASRLARTVRSDAFTVTVNRDFKGVIDGCAAPQPGRDDTWINRRIRELYIGLHGIGHCHSVEVWQDGDLAGGLYGVSLGRAFFGESMFHRARDASKVALVHLVARLLAGGYELLDTQFVTDHLRSFGAIEVPRQRYRSMLDDALQGIAAFDALPVDQPVTGAKALEIIAAH
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAMA_KLEPN
Sequence: MTISAQVIDTIVEWIDDNLHQPLRIDDIARHAGYSKWHLQRLFLQYKGESLGRYIRERKLLLAARDLRDTDQRVYDICLKYGFDSQQTFTRVFTRTFNQPPGAYRKENHSRAH
What is the function of this protein?
Probable transcriptional activator.  Confers a multidrug resistance phenotype in E. coli.
What are the official names of this protein?
Transcriptional activator RamA.
Protein: ECTP_CORGL
Sequence: MSSNIAITTEPEGKNKKGLKSDPFIFSISVGFIVVFVIATIALGEKARTTFSAIAGWLLENLGWMYIGGVSLVFIFLMGIFASRYGRVKLGDDDDDPEHTLIVWFCMLFAGGVGAVLMFWGVAEPINHAFNVPMANEESMSEAAIVQAFAYTFYHFGIHMWVIMALPGLSLGYFIYKRKLPPRLSSVFSPILGKHIYSTPGKLIDVLAIVGTTFGIAVSVGLGVLQINAGMNKLWSTPQVSWVQLLIILIITAVACISVASGLDKGIKLLSNINIAMAVALMFFILFTGPTLTLLRFLVESFGIYASWMPNLMFWTDSFQDNPGWQGKWTVFYWAWTICWSPYVGMFVARISRGRTVREFIGGVLALPAIFGVVWFSIFGRAGIEVELSNPGFLTQPTVVEGDVPAALFNVLQEYPLTGIVSAFALVIIVIFFITSIDSAALVNDMFATGAENQTPTSYRVMWACTIGAVAGSLLIISPSSGIATLQEVVIIVAFPFFLVQFVMMFSLLKGMSEDAAAVRRVQTRQWEKTDTPEKLEEHSSQPAPGYDDEGNPLPMPALEHDEDGNIVIPGNVVIEGDLGVVGDVVDDPEEAQEMGSRFKIVEQTRPQSRDEYDI
What is the function of this protein?
Involved in the uptake of osmoprotectants.  Can transport ectoine, proline and glycine betaine.  Na(+) is probably the coupling ion.
What are the official names of this protein?
Ectoine/glycine betaine/proline transporter EctP.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: M313B_XENLA
Sequence: MHLNDIMASPHEPLNWSSSPNLIVDTIQEDKDYRVDYGDCTTIGHHEIKETPDKCDFLDNTNSPVNATVLNSISEDSRDQFENSVLQLRDQDEPENTAPQGSSHSGDGGNNSANEDIRIHFSRSRSGSGNGGFLEGLFGCLRPVWNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRGEEVAIKKVREQKETDIKHLRKLKHPNIIAFKGVCTQAPCYCILMEYCAQGQLYEVLRAGRKVTPKLLVEWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHADTVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVLLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQILMHLDIAAADVLGTPQETYFKSQAEWREEVKKHFEKIKSEGTCIHRLDEELIRRRREELRHALDIREHYERKLERANNLYMELSSIMLQLEVREKELTRREQTVEKKYPGTYKRHPVRPIVHPNSFEKLIKKKGPPSRVPSQSKRPDLLKSDGIVNAEGSAASASPISGSPKTSSGGGKGRYRSKPRHRRGNSKGSHADFVGVLKYQESPAPSQQSSQHQTPASPPVTPCSPYHETSQVMPTRHQTLNVHGQNIANCANNLRYFGPAAALRSPLSSHAHRRMSGFSPDLLSSTLEADSRIQPEREYEYCEQHPYNPSQGCTETSVQHDIDTENLNNTNVVTAEYRTSDGDLPDSPRHNLVQEDYEKLETGGEQFSSLKAAVGVSALTVPTPPALPRRIHTLRKNGDDSSEGEEGEVDSEVEFPRRHRPPRGMSTCQSYSTFSSENFSVSDGEEGNTSDHSNSPDDVACGNKVWQVDKLDDLLSQTPEIPIEISMQSDGLSDKECAVRRVKTQMSLGKLCPEEHNYENAESDCDSSEGECSDATVRTNNPVNSSTW
What is the function of this protein?
May have a role in the JNK signaling pathway.
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 13-B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: LEU1_DECAR
Sequence: MKQHLVIFDTTLRDGEQSPGASMTKEEKIRVARQLEKMRVDVIEAGFAAASPGDFDAIHSIAQTIKDSTVCSLARANENDIRRAGEAIKPAQSGRIHTFIATSPIHMEKKLRMTPDQVVEQAVKAIGWAREYTDDIEFSAEDAGRSDLDFLCRIFEEVIKAGATTINVPDTVGYNIPSQYAETMRQLIERVPNSDKVVWSVHCHNDLGLAVSNSLAAVLCGARQVECTINGLGERAGNAALEEIVMAVRTRADVFPVETRIDTTQIVPASKLVSQITGYPVQPNKAVVGANAFAHESGIHQDGVLKHRETYEIMRAQDVGWTQNKLVLGKHSGRNAFKNRLQELGIELESDEALNAAFARFKELADKKHEIFDEDLHALVSDDLVTPDQEYYKLVYSRVCSETGEMPRASVILNIGGVEHKAEADGGGPVDATFKAIESIAGSGAELLLYSVNAITTGTDAQGEVTTRLSKGDRIVNGNGADTDIVIASARSYLNALNKLHSTLDKVKAQGGV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: DNAK_PELPB
Sequence: MGKIIGIDLGTTNSCVSVMQGSQPTVIENSEGNRTTPSIIALTKTGDRLVGQAAKRQAITNPKNTIFSIKRFMGRKYDEINDEKKLAPYEIINEGGEARVKINDKIYSPQEVSAMILQKMKQTAEDFLGEKVTEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDRKQTSEKVAVFDLGGGTFDISVLELGDGVFEVKSTDGDTHLGGDNFDQKIIDYIADEFKKQEGIDLRKDAITLQRLKEAAEKAKIELSSRTDTEINLPFITATQEGPKHLVINLTRAKFEALCADLFDKILDPCRRAIKNSKLEMKEIDEVVLVGGSTRIPKVQALVKDFFGKEPNKSVNPDEVVAIGAAIQGGVLKGDVTDVLLLDVTPLSLGIETLGGVMTKLIDANTTIPTRKQEVFSTAGDNQTSVEVHVLQGERPMATDNKTLGRFHLGDIPPSPRGIPQIEVTFDIDSNGILHVSAKDKATGKEQSIKIESSSKLTDAEISKMKEDAKEHAAEDQKRKEEIDTRNIADSLIFSTEKQLKELGDKIPADKRPVLEGSLEKLKEAYKNGTVESLKSAMEELNKEWSEIASHLYQSQGPESSQPETAAQSDSGEKSKKNSGDGNVENAEYEVIDGNDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RPOB_BRUA4
Sequence: MAQTHSFNGRKRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVEEPSGGRSDEGLQAVFKSVFPIQDFSGASMLEFVRYEFDAPKFDVDECRQRDLTYSAPLKVTLRLIVFDIDEDTGAKSIKDIKEQDVYMGDMPLMTDNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAARVIPYRGSWLDIEFDSKDIVYARIDRRRKLPATTLLMALGMDGEDILSTFYKTVTYTRDGDNWRIPYSADRFKGMKIISDLIDADTGEVVLEAGKKLTARSAKQLAEKGLKAIKATEDDLFGSYLAEDVVNYATGEIYLEAGDEIDEKVLKTLIDTGETEINVLDIDHINIGGYIRNTLAVDKNESRQEALFDIYRVMRPGEPPTMDSAEAMFNSLFFDAERYDLSAVGRVKMNMRLDLDAEDTVRVLRKEDILAVVKMLVELRDGRGEIDDIDNLGNRRVRSVGELMENQYRVGLLRMERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKVVDGKVTNDVVYLSAMEEAKHSVAQANVELDERGGFVDEFVICRHAGEVMMAPRENVDLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMEAVVARDSGAAIAARRGGVVDQVDATRIVIRATEDLDPSKSGVDIYRLMKFQRSNQNTCINQRPLVRVGDPIQKGDIIADGPSTDLGDLALGRNVLVAFMPWNGYNYEDSILLSEKIVSDDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVHPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTYGTVVEVRVFNRHGVEKDERAMAIEREEIERLAKDRDDEQAILDRNVYGRLADMIDGKVAAAGPKGFKKGSTITRELMTEYPRSQWWQFAVDDEKLQGELEALRGQYDESKKLLEARFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRILPVEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLGWACAGMGKKIGELIDVYRKTANIEPLRDTLEHIYPDNDRNEPVRSYDDDSVLMLANQVKRGVSIATPVFDGAVEADINAMLTDAGLATSGQSTLYDGRTGEPFDRQVTMGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELDDTRDEQQQALPDAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL1_PSET1
Sequence: MAKLTKRMRTIREKVEVTKDYEINEAIALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPNGTGRDVRVAVFTQGANAEAAKEAGAELVGMEDLAELVKKGEMNFDVVVASPDAMRVVGQLGQILGPRGLMPNPKTGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFTAEQLQQNLESLIVALKKAKPSQAKGVYVKKVSISTTMGAGVAVDQNTLSTTVA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RS8_VIBA3
Sequence: MSMQDPISDMLTRVRNGQAANKVAVKMPSSKLKVAIAALLKAEGYIVDFAVDSEAKPELEVTLKYFQAKPVIEQIKRVSRPGLRVYKNKDSLPTVMGGLGIAVVSTSKGLMSDRAARKAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: DXS_BRASO
Sequence: MTTFSKTPLLDTIKTPEDLRRLKVEQVRQVADELRQETIDAVSVTGGHFGAGLGVVELTTAIHYVFDTPRDRLIWDVGHQAYPHKILTGRRDRIRTLRTGGGLSGFTKRAESDYDPFGAAHSSTSISAGLGMAVARDLSGGKNNVIAVIGDGAMSAGMAYEAMNNAGAMNSRLIVILNDNDMSIAPPVGAMSAYLSRLYSGKTYRTLRDAAKQLGQHLPKVIANRASRVEEYSRGFMMDGGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDMETGPILVHVVTQKGKGYSPAEAAADKYHAVAKFDIATGTQAKAKPNAPAYQNVFGQSLVKEAEKDEKIVGITAAMPSGTGIDIFAKAFPKRTFDVGIAEQHAVTFAAGLAAEGYKPFCAIYSTFLQRGYDQIVHDVCIQSLPVRFAIDRAGLVGADGATHAGSFDNAYLGCLPNMVIMAASDEAELVHMVATQVAIDDRPSSVRYPRGEGRGVEMPEVGVALPIGKGRMIRQGKQVALLSFGTRLAECEKAADELAAHGLSASIADARFMKPLDEELVLKLARDHEILITIEEGSIGGFGSHVMQYLADQGMLDGGLKMRSMVLPDEFQDHDTPAAMYARAGLDAKGIVRKVFEVLGKDYAAEAVKLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: GLNB_PORPU
Sequence: MKKIEAIIRPFKLNEVKLALVKGGIGGMTVVKVSGFGRQKGQTERYKGSEYSIDIIDKIKIEIIVSDDKVNSITEIIIKTAKTGEIGDGKIFISDVEQVIRIRTNDLNSAAL
What is the function of this protein?
P-II indirectly controls the transcription of the glutamine synthetase gene (glnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA.  When P-II is uridylylated to P-II-UMP, these events are reversed.  When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase, so activating the enzyme (By similarity).
What are the official names of this protein?
Nitrogen regulatory protein P-II.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRUB_NEIG1
Sequence: MTNKPAKRPVNGVLLLDKPEGLSSNTALQKARRLFHAEKAGHTGVLDPLATGLLPVCFGEAAKFAQYLLDADKAYTATLKLGEASSTGDAEGEIIAAARADISLAEFQTACQALTGNIRQVPPMFSALKHEGKPLYEYARKGIVIERKPRDITVYSIDIAEFDAPKAVISVRCSKGTYIRTLSEGIAKHIGTFAHLTALRRTETAGFTIAQSHTLEALANLNETERDGLLLPCDVLVSHFPQTVLNDYAVHMLQCGQRPRFEEDLPSDTPVRVYTENGRFVGLAEYQKEICRMKALRLMNTAASSA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: EFPL_XANOM
Sequence: MKANDIKKGNVVEYNGGIYQIRDIERSSPQGRGGNVRFRFIMYSVPGGVKTDASLDADDNLPDVELLRRLSTFSYKDGEAFVFMDDEDFTPYTLDADVIGTDAGYITDGLTGIYVQVIDDQPVAVQLPQTVTLEVVETPPELKGGTATKRPKPAKLNTGMEIMVPEYITNGERVLVNTTTGEFAGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: MOAA_RHOPS
Sequence: MSSAVMTPPTVGASAMTDPFGRTISYLRVSITDRCDFRCVYCMSEDMTFLPRADLLTLEELDRLCSAFIARGVRKLRLTGGEPLVRRNMMSLVRSLSRHLGTGALDELTLTTNGSQLARFAEELSDCGVRRINVSLDTLDPGKFRAITRWGDLDRVLAGIEAARAAGLAVKINAVALKNINEDEIPSLMQWAHGLGMGLTLIEVMPLGEIGEGRIDQYVPLSLVRARLSNNYTLTDLPDSTGGPARYVRVDETGGKLGFITPLTHNFCESCNRVRITCTGTLHTCLGQEDASDLRRPLRASPDDDLLNAAIDRAIGHKPKGHDFIIDRKHNRPSIGRHMSVTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: VCY1_HUMAN
Sequence: MSPKPRASGPPAKAKETGKRKSSSQPSPSGPKKKTTKVAEKGEAVRGGRRGKKGAATKMAAVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSKGRPSTPLSP
What is the function of this protein?
May mediate a process in spermatogenesis or may play a role in sex ratio distortion.
What are the official names of this protein?
Testis-specific basic protein Y 1, Basic charge, Y-linked 1, Variably charged protein Y.
What is the protein family that this protein belongs to?
Belongs to the VCX/VCY family.
Protein: BMP1_MOUSE
Sequence: MPGVARPPLPLLSLPLLLLLLLLPRAGRPLDLADYTYDLGEEDAPELLNYKDPCKAAAFLGDIALDEEDLRAFQVQQAAVLRQQTARRPSIKAAGNSSALGGQGTSGQPQRESRGRWRGRPRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYIELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTKFQDTLHSRK
What is the function of this protein?
Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins.  Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair (PubMed:24419319, PubMed:8951074, PubMed:28068493).  Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers (PubMed:20181949).  Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation (By similarity).
What are the official names of this protein?
Bone morphogenetic protein 1, BMP-1, Mammalian tolloid protein, mTld, Procollagen C-proteinase, PCP.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Secreted, extracellular space, extracellular matrix. Secreted. Note=Co-localizes with POSTN in the Golgi.
Protein: BUD31_RAT
Sequence: MPKVKRSRKAPPDGWELIEPTLDELDQKMREAETEPHEGKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGRIIECTHCGCRGCSG
What is the function of this protein?
Involved in the pre-mRNA splicing process.  May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity.
What are the official names of this protein?
Protein BUD31 homolog, Protein EDG-2, Protein G10 homolog.
What is the protein family that this protein belongs to?
Belongs to the BUD31 (G10) family.
Protein: PSBT_SYNJB
Sequence: MEAITYTFILFLTLGLLFFAVAFRETPRITKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: TR2M_PSESS
Sequence: MYDHFNSPSIDILYDYGPFLKKCEMTGGIGSYSAGTPTPRVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAEMGAMRFPPSATGLFHYLKKFGISTSTTFPDPGVVDTELHYRGKRYHWPAGKKPPELFRRVYEGWQSLLSEGYLLEGGSLVAPLDITAMLKSGRLEEAAIAWQGWLNVFRDCSFYNAIVCIFTGRHPPGGDRWARPEDFELFGSLGIGSGGFLPVFQAGFTEILRMVINGYQSDQRLIPDGISSLAARLADQSFDGKALRDRVCFSRVGRISREAEKIIIQTEAGEQRVFDRVIVTSSNRAMQMIHCLTDSESFLSRDVARAVRETHLTGSSKLFILTRTKFWIKNKLPTTIQSDGLVRGVYCLDYQPDEPEGHGVVLLSYTWEDDAQKMLAMPDKKTRCQVLVDDLAAIHPTFASYLLPVDGDYERYVLHHDWLTDPHSAGAFKLNYPGEDVYSQRLFFQPMTANSPNKDTGLYLAGCSCSFAGGWIEGAVQTALNSACAVLRSTGGQLSKGNPLDCINASYRY
What are the official names of this protein?
Tryptophan 2-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2-monooxygenase family.
Protein: DAPB_LEGPL
Sequence: MRTRVIVNGANGKMGILACETLENHEQFEVVAKLSRQDNLGQSILDTKAQIVVDLTRADCVYENSLTIINHGARPVIGTSGLVETQIDELTKLCKIKQIGGIIAPNFSLGAILMMMLAAKASEYFSEVEIIEGHHQQKLDAPSGTALKTAEMMAAARKKPKNKLPLKELTPGARGGSHHDINIHSLRLPGLLARQEVLFGNIGETLSITHNSIDRRCFMPGIVLACQKVLNLTNLVYGLEHLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRAB_STRGC
Sequence: MAEIYLAGGCFWGLEEYFSRIEGVKKTTVGYANGQVESTNYQLIHQTDHAETVHLIYDEKRVSLREILLYYFRVIDPLSVNKQGNDVGRQYRTGVYYTNQADKAVIEQVFAEQEKQLGQKIAVELEPLRHYVLAEDYHQDYLKKNPGGYCHINVNDAYQPLVDPGQYEKPTDAELKEQLTQEQYQVTQLSATERPFHNAYNATFEEGIYVDVTTGEPLFFAGDKFESGCGWPSFSRPIAREVLRYYEDKSHGMERIEVRSRSGNAHLGHVFTDGPESAGGLRYCINSAALRFIPKEKMEAEGYAYLLQHMK
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).  Involved in protection against oxidative stress when the bacterium enters the host bloodstream and required for maximal growth under aerobic and anaerobic conditions.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA/MsrB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
Protein: GMHA_ECO5E
Sequence: MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_SALDC
Sequence: MRVVILGSGVVGVTSAWYLSQAGHDVTVIDRESGPAQETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTPFQLKWMWQMLRNCDTRHYMENKGRMVRLAEYSRDCLKTLRAATGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLARMAEQAGVTFRFNTPVEKLLYENDQIYGVKCADEIIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIVEPDGAPVSTILDETYKIAITRFDKRIRVGGMAEIVGFNTDLLQPRRETLEMVVRDLFPRGGHIEQATFWTGLRPMTPDGTPVVGRTRYKNLWLNTGHGTLGWTMACGSGQLLSDILSGRTPAIPYDDLSVARYRSDFTPTPPQRLHSAHN
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: NTPPA_SACD2
Sequence: MTTSSHHNKGDNSADLYLASQSPRRRELLAQIGVKVAVLSVDVAEQREVGESPAQYVQRLAYDKAMAGAKLAATQPRSLPCLGSDTIVVIENRVLEKPRDEEDGVAMLLALSGQTHQVMTAVAVATEAKQLMRLSVTDVTFREISRAEAIEYWRTGEPADKAGGYGIQGLGAVFVRELKGSYTAVVGLPLFETKTLLDAFEVPVWQNLAP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRDB_NATTJ
Sequence: MADLKVNFAGIPMKNPVASASGTFGFGFEYQSVISPHELGALVVKGLTLSPKRGNQGTRLHETASGLLNSIGLENPGIDNFINEILPDLRQCDATTLINISGGNDEEYVEITQKLNNCQGIAGLEVNISCPNIREGGLVYGVDPELTYRLVSKVRQSTSFPVIVKLSPNVTDITEIAKACERAGADGLSLINTVAGMAIDIDQKEPVFDNISAGLSGPAIKPIALKAVYQVSQAVDLPVMGMGGIYNYQDAIEFILAGATSVALGTVNFAEPTAAKSIIQGIDNYLEREGYLSVNDIRGLAWK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.