PharMolix/UniProtQA huggingface dataset:
Protein: SECA_MYCS5
Sequence: MAFFSKFLNIKSTEMRIAEKSLKRINDLEKYVINNTDEELRSKTQFFKDLLKEGYKLEDIRDEVFAVAREATKRVLGKRPYDVQILGGILLDLGSVAEMKTGEGKTITSIAPVYLNALSGKGAIVSTVNEYLTERDAQEMGQVFNYLGLSVGINKAQMDPNLKRYAYSCDITYSVHSELGFDYLRDNMVSDMSEKVQRELNFCLIDEVDSILIDEAKTPLIISGGEANDSSSYYSADQFVRTLNNDDFLVDEESKAVTLTASGIEKANSFFRIDDLYNIEHSEKVHLIQNALRAHKVFKIDVEYIVKNNKIELVDAFTGRIMEGRSYSEGLQQAIQAKEMVEIEPETQTLATITYQNFFRMFNKLCGMTGTGKTEEQEFIDIYNMRVNVVPTNKPIAREDAPDLIFATAKDKWEAVGKEVERLYQKGQPVLVGTAQIEDSEIIHRILIEKNVPHTVLNAKQDKALEAEIIAQAGVKGAVTIATNMAGRGTDIKPSKEALELGGLYVLGTDKAESRRIDNQLRGRSGRQGDVGISRFYISLEDQLIMRFANFEAFQEVYAKDAGKEITNKQLRFAFNNAQKKIEGFNYDSRKSVLNYDDVIRQQRDLIYSQRDLLLISNEFEEIIRRMIKVFVKNLVAIEDHKLKSGAYDYQKLVDFLNKNIAVYIKHDFNVDEFKRIHDNELVDKVNQMVNDIYNQWLANAIEKTDQAYIDNFKKQVLLKTLDDNWKKHINKMDKLRSNVNLVQYSQKNPYQIYTDEGTKMFEDLIQTIAFESVLKVFSSPLGEKSLITAEIKNDPLYQQVASTFEYNPYLSISEQEKQLLERYNNVKQRLNEVEQQNLQEQSYKDPASDNLENNPEPKTGSQSQSEHEMVLTPDTVIDPSIDTNQWFEEINIDDFINVTKKDSELESKEKEQEEVKNQETQPKENKPAETKVDATKNQENVSEELKAKEVATVVEEKPKKVSKAKSEKLKVAKKVKPKDLESKEKPKSDKAKKSLAKKETQKPKKPKITSEVKIAKVEKTNKKAKAQDKPKAKVTKAKETKPKTEVKADKVKTKTAKTSEAKAQKVEAENFVNKIVFPKNKIDLKLEKIKLK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: CHO90_HUMAN
Sequence: MASSCPGTPSPAGLPPPSVATPGETLGPAAPPEPAFPDIYGGDAQLWEAHFRGIGRAYRALGKQDDFAIRVLTENFTLPFPFAWPPGSDPACGPLFYDPRDRADFDFLLRGPGASPPALLRPLHATAQAAMRKRRLERLALSCARARGPGPASSCCCPAPPPPSRSPRPALPATAPPGWPRPRRCPESEQNK
What are the official names of this protein?
Uncharacterized protein C8orf90.
Protein: BTUC_SALAR
Sequence: MDNMLTFARQQQRRNVRWLLSLSLLVLLATLLSLCAGEQWIAPGDWLSSRGELFVWQIRLPRTLAVLLVGASLALSGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPGWSLGLCAIAGALTITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSFDLRQLMYWMMGGFGGVDWQQSWLMTALIPVLIWICCQSQPMNILALGETPARQLGLPLWLWRNLLVVATGWMVGVSVAMAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGAIALLLADVVARLALASAELPIGVVTATLGAPIFIWLLLKSAR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YGDH_SCHPO
Sequence: MKQSRTKRVLAIGELKFATNTLKRLSEKYHFEFIVPDPHDRSKTIEKIHEAASKSTFDACFWLFRNAAISPFTEEMLGPLLPTCKLFVTGAAGYNNVDVDWATRNGVYVANTPNGPTEGTANMNLMLFMCTLRGAREAEQSLRLGKWRQNLSLTDDPYGKRVGIIGMGAIGKSFAQKILPLGCEIVYHNRNRLEAEEEKRLGASFVSFDELLSSSDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKSGKVARAGLDVFLNEPTPNKFWLECDKVTIQPHCGVYTNFTVAKTEECVLASIETFLDTGIPTNPVNGPFGMNGC
What are the official names of this protein?
Putative 2-hydroxyacid dehydrogenase C1773.17c.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: GUAA_NOSP7
Sequence: MNTVVTLPTEQAPQTLENVGRFDRPLIIILDFGSQYSELIARRIRETQVYSEVLSYRTTSEQLRQLNPKGIILSGGPSSVYGDNAPHCDPEIWNLGIPVLGVCYGMQLMVNQLGGEVAKADRGEYGKASLYIDDPTDLLTNVEDGTTMWMSHGDSVTQMPSGFELLAHTENTPCAAIADHERKLYGVQFHPEVVHSIGGIALIRNFVYHICDCEPTWTTAAFVEEAIREIRTRVGEKRVLLALSGGVDSSTLAFLLYKAIGEQLTCVFIDQGFMRKYEPERLVKLFQEQFHIPVEYVNARDRFLAKVAGVTDPEEKRRRIGHEFINVFEETSKRLGHFDYLAQGTLYPDVIESADTNADPQTGERVAVKIKSHHNVGGLPKDLRFKLVEPLRKLFKDEVRKVGRSIGLPEEIVQRQPFPGPGLAIRILGEVTSERLNILRDADLIVRQEINQRGMYHDFWQAFAVLLPIRSVGVMGDQRTYAYPIVLRIVTSEDGMTADWARVPYDVLEVISTRIVNEVKGVNRVVYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: PSBI_CALFG
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL37_HALLT
Sequence: MTGSGTPSQGKKNKTVHVKCRRCGEKSYHVKKERCSSCGFGDSASRRGYAWQSKSGDN
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: Y1478_PASMU
Sequence: MKEFQFDTLWAVMQIMLGAFFWPALIVIILTIAAFCYLLIKEKGLVACRLKGSSLVGLLGGILALYLLFSISQASISDIGGPIDLILVVLAYFGGFLASTMLLYSIIGFVKPRSCACQKN
What are the official names of this protein?
Uncharacterized protein PM1478.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCX1_TITBA
Sequence: MKGMILFISCLLLIGIVVECKEGYLMDHEGCKLSCFIRPSGYCGSECKIKKGSSGYCAWPACYCYGLPNWVKVWDRATNKCGKK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  Is lethal to mice (PubMed:8611151).
What are the official names of this protein?
Toxin Tb1, PT-Mice-beta* NaTx6.2, Tb-gamma.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBL_CROS5
Sequence: MDRNQNPNRQPVELNRTSLYLGLLLIAVLGILFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ATP6_ECODH
Sequence: MASENMTPQDYIGHHLNNLQLDLRTFSLVDPQNPPATFWTINIDSMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYE_BORHD
Sequence: MNIRVRYAPSPTGLQHIGGIRTALFNYFFARSCGGKFLLRIEDTDQSRYFQEAEEDLYQSLKWLGIDFDEGPTCGGPYEPYVQSKRTAIYQKYAKQLIELGNAYYCYCKPDRLERIRKIQTVNKMAPGYDRHCRNLSESEIKDVLSLGITPVIRFKIPLDGETCFNDILLDKVTWANKDISPDPVILKSDGLPTYHLANVVDDHLMEISHVLRAQEWVSSGPLHVLLYNAFGWKPPIYCHLPMVMGSDGQKLSKRHGATALKQFIADGYLPEAIINYITLLGWSYDDKSEFFTKNELQRLFSIERVNKSPAVFDYNKLDFFNSHYIREKGDDELAKLLIPFLQKAGYIKEDINSCDEQKLMLLIPLIKPRIRKLSEAVTMLKFFYEDIKTWNLDEFLGKKKTASDIYLLLEKIKPVLEDFETRMLPDNEKIFYNFAKENNLKIGEVLLPIRIAVLGSKVSPPLFDSLQLLGKVKVFDRISQAQQFLKRHEL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_HALSA
Sequence: MDVYGLIGNPVGHSLSPPLHAAAYDECGLDARYVTFEPAPDDAAAAIRGAGALGVAGLNVTAPFKQSAASAVATDSMAARVGAVNTIDFSGAAPRGYNTDVAGVKRAFAHHDVSLSGAQAVVVGAGGAGRAAAFALADAGATVRIANRTRAAADELAADVGGTAVGLGDLPRSLADATVLVHATTVGMDDPDTSPVSADALHDDLAVLDAVYSPVETRLLRDAAAAGATTIDGAWMLLYQGAEAFERWTGLDAPVAAMRAALRARL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: YR517_MIMIV
Sequence: MEIINSRYKMTDTVLGKGGFSEVFLGTDMYTDNKVAIKKINITGKNSSDIKFLNKLDFEIRTMQILNHPNIVAYYDVMKTENYWYIVMEYCNFGTLNDVIKFNKNKGISSLDLEKNTHYYLNQLRDALNYIINMGYIHRDIKPMNILLTKSISENNENNENTNYDRSNSLILKLADFGLTKKCSENEEDIMNTICGSPLYMAPELFFNQHYNSQSDIWSFGIIMYQLLFHDHPINATNYSQLKNGLKNQKINFPKNNMFSNYCFDLLSKTLAKDPKNRLNWSELFHHYWFIHWSEQHCPKNKSDDSNNKKIPDKSQFNEILSSTKSPLISLRQFGQLGQSNLSKFKNNGAINCSIDFPKYTNNFPSAVNQSIKIGLSGSSSPINIPVRNNSSKKINYDDIELISNGNIFPETLYGSISPVDSIINKETRNKTNNPSSLNLSEFVLSDYEI
What are the official names of this protein?
Putative serine/threonine-protein kinase R517/R518.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: MURC_PHOLL
Sequence: MNTQQLAKLRAFVPEMRKVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTRQLTKLGAQIYFNHRPENILDASVVVASSAILADNPEIVAAREARIPVIRRAEMLAELMRYRHGIAIAGTHGKTTTTAMISSIYAQAGLDPTFVNGGLVKAAGTHARLGSSRYLIAEADESDASFLHLQPMVAVITNIEADHMDTYHGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVKELIPRVGRYITTYGFSEEADVRITHYQQKGAQGYFTVSRQDMADLKVVLNAPGRHNALNAAAAVAVATEEGISGSDILAALAGFQGTGRRFDFLGNFSLEHVNGKGGSAMLVDDYGHHPTEVDATIKAARAGWPDKRIVMIFQPHRYTRTRDLYDDFANVLNQVDVLLMLDVYSAGEVVIPGADSRSLCRTIRSRGKLDPILVSDPAKVTAVLAQVLDGHDLILVQGAGNIGKIARNLAETKLQPSLNEEKHNG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_SHEB8
Sequence: MQDIQLDTLLSEDVTPENASQVMQALSQSLNEHNIRYYVDDAPSITDSEYDRLMQRLLKLEALYPHLIVADSPTQRVGGLALAKFDQITHLKPMLSLDNAFDEADFSAFHKRVTDKVGEVSFCCEPKLDGLAVSILYRHGVLERAATRGDGSVGEDITENVKTIKSIPLKLRGNDFPELVEVRGEAFMPKAAFEALNDRARAKDEKLFVNPRNAAAGSLRQLDSKITAARSLAFYAYALGVVEPDSHPLAKTHFEQLQQLKSWGLPISSEIKVCAELSQVYDYYKNILTRRSDLAFEIDGVVMKVNDIAQQQRLGFVAKSPRWAIAYKFPAQEEMTLLEGVDFQVGRTGAVTPVARLKPVFVGGVTVSNATLHNADEIARLGIKVGDTVIIRRAGDVIPQIVAIVPERRPETATDIVFPHNCPVCGSLVERLEGEAVARCSGGLFCEAQRKEAIKHFASRKALDIDGMGDKVVEQLIDKELVQSPADLFKLTASMMTMLDRMGMKSATNLAAAIEAAKTTTLARFLYALGIREVGEATAANLAAHFASLDALRVATVEQLTEVEDVGAVVAQHVAHFFAQPHNLEVIDALIAAGVHWPAIEAPSADAQPLKGQTWVLTGTLNQLNRNDAKAQLQALGAKVAGSVSKNTDCLVAGEAAGSKLAKAQELGVKVMDEDELLALLAANA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DER_ECO57
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGSPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: 020R_FRG3G
Sequence: MLQNYAIVLGMAVAVAIWYFFKIEEEAPPGPNPPKPDPPKPDPPKMHMPKKKPHWMDPHLTGSQTVQYSRNRSMGDPIRGDLPIIPRDDGWFSTAANPAHTLHAGALSMIAPASTGGGLTVNKLISAYADKGNAMSGRHNSPSYYGSS
What are the official names of this protein?
Uncharacterized protein 020R.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: VP35_EBOZ5
Sequence: MTTRTKGRGHTAATTQNDRMPGPELSGWISEQLMTGRIPVSDIFCDIENNPGLCYASQMQQTKPNPKTRNSQTQTDPICNHSFEEVVQTLASLATVVQQQTIASESLEQRITSLENGLKPVYDMAKTISSLNRVCAEMVAKYDLLVMTTGRATATAAATEAYWAEHGQPPPGPSLYEESAIRGKIESRDETVPQSVREAFNNLDSTTSLTEENFGKPDISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQASLAEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPPSPKIDRGWVCVFQLQDGKTLGLKI
What is the function of this protein?
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling.  Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes (By similarity).  Serves as nucleoprotein/NP monomer chaperone prior to the formation of the large oligomeric RNA-bound complexes (By similarity).  Regulates RNA synthesis by modulating NP-RNA interactions and interacting with DYNLL1.  VP35-NP interaction controls the switch between RNA-bound NP and free NP and thus the switch between genome replication and genome packaging into the nucleocapsid.  Prevents establishment of cellular antiviral state, thereby suppressing host DC maturation.  Acts by inhibiting host RIGI activation both by shielding dsRNA from detection and by preventing PRKRA binding to RIGI.  Blocks virus-induced phosphorylation and activation of interferon regulatory factor 3/IRF3, a transcription factor critical for the induction of interferons alpha and beta.  This blockage is produced through the interaction with and inhibition of host IKBKE and TBK1, producing a strong inhibition of the phosphorylation and activation of IRF3.  Also inhibits the antiviral effect mediated by the host interferon-induced, double-stranded RNA-activated protein kinase EIF2AK2/PKR.  Increases PIAS1-mediated SUMOylation of IRF7, thereby repressing interferon transcription (By similarity).  Also acts as a suppressor of RNA silencing by interacting with host DICER1, TARBP2/TRBP and PRKRA/PACT (PubMed:21228243).  As a dimer, binds and sequesters dsRNA contributing to the inhibition of interferon production (By similarity).
What are the official names of this protein?
Polymerase cofactor VP35, Ebola VP35, eVP35.
What is the protein family that this protein belongs to?
Belongs to the filoviridae polymerase cofactor VP35 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: FTNA_ECOLI
Sequence: MLKPEMIEKLNEQMNLELYSSLLYQQMSAWCSYHTFEGAAAFLRRHAQEEMTHMQRLFDYLTDTGNLPRINTVESPFAEYSSLDELFQETYKHEQLITQKINELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGEGLYFIDKELSTLDTQN
What is the function of this protein?
Iron-storage protein.
What are the official names of this protein?
Bacterial non-heme ferritin, Ferritin-1.
What is the protein family that this protein belongs to?
Belongs to the ferritin family. Prokaryotic subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA2_GLOVI
Sequence: MLAMSHQTASSRLPEWARRTIGTASQVSTVEKIVKQRSLHTICEEGRCPNRAECYAQKTATFLLMGPVCTRACGFCQVAGGKALPLDPQEPEKVAEAVALLGLKYVVLTSVARDDLPDQGAGWFVRTMESIRARNCAVEIEVLTPDFRGEEACIATVVAARPVCFNHNIETVRRLQSYARRAATYARSLAVLAAVKRLDAEIFTKSGLMLGHGETREEVLETLLDLRKVGCDRVTLGQYLQPSKDHLPVHKYWTPAEFAELGAVARDLGFAHVRSGPLVRSSYHAGEPE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase 2, Lip-syn 2, LS 2, Lipoate synthase 2, Lipoic acid synthase 2, Sulfur insertion protein LipA 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLASR_MOUSE
Sequence: MWHEARKHERKLRGMMVDYKKRAERRREYYEKIKKDPAQFLQVHGRACKVHLDSAVALAAESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTPPLLTTISPEQESDERKCNYERYRGLVQNDFAGISEEQCLYQIYIDELYGGLQRPSEDEKKKLAEKKASIGYTYEDSTVAEVEKVAEKPEEEESPAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPSPGREEKITFITSFGGSDEEAAAAAAAAAASGAAPGKPPAPPQTGGPAPGRNASTRRRSSSSSASRTSSSRSSSRSSSRSRRGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSDGGSRDGHRYSRSPARRGGYVPRRRSRSRSRSGDRYKRGARGPRHHSSSHSRSSWSLSPSRSRSVTRSGSRSQSRSRSRSQSHSQSQSHSPSPPREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQERLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYRH
What is the function of this protein?
Probably functions as an alternative splicing regulator.  May regulate the mRNA splicing of genes such as CLK1.  May act by regulating members of the CLK kinase family.
What are the official names of this protein?
CLK4-associating serine/arginine rich protein, Clk4-associating SR-related protein, Serine/arginine-rich splicing factor 16, Splicing factor, arginine/serine-rich 16, Suppressor of white-apricot homolog 2.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus. Note=Located in nuclear dots. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus, nucleoplasm.
Protein: RL36_DESVV
Sequence: MKVRPSVKKICPKCKVIRRRGVLRVICENPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RUVC_STUS1
Sequence: MTLILGIDPGSRITGYGVVRDTGRGCEYVASGCIRTGSGELSERLRAVFSGVSEVIRTYGPVTMGIEQVFMARNADSALKLGQARGAAIVAGAEAGLQIAEYTATQVKQAIAGTGGADKQQVQMMVMHLLKLLEKPQIDASDALAIALCHAHHRQSLVPHGLIGAKRRGGRLRL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PSBH_MORIN
Sequence: MATQTVEGSSRSGSRRTSVGNLLKPLNSEYGKVAPGWGTTPLMGIAMALFAIFLSIILEIYNSSILLDGISMN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GATB_BORBU
Sequence: MEYKLVIGLEIHVQLGLKTKAFCGCKNEFGGVPNSRVCPICLGLPGSLPSVNVELINSAILAGHATNSKIRNVVKFDRKHYYYPDLPKGYQISQNDKPICEGGSLLIETPSGPKKINIIRIHMEEDSGKSLHLLDSENQSYVDFNRSGAPLLEIVSAPDINSGDEAVAFLSSLREIFRYLDLSECNMENGSFRCDVNVNLIVKENGVEHKTPIAEIKNLNSFKSIKAAIEYEELRQQQEWIQFKKTLNSCGKHTRGFDDRSGVTVIQRNKETVSDYRYFQEPDLPLIEIDDSYIDNIKNLKLIELPFHARIRLKGQYGLSDFDVITLTADKHLLKYFEEAVINSSDPKKVANWILSEVLSVLNDKGISVLEFNLLPSYITELVEFIVAGKISGKMAKRVFSEMMTRGVSASVVISENQLEQVSDKFVIKQIVLEVLDENPKSIELYKKGKDHAIKFMMGQIMKKSSGKINPILANEILLESLSNV
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: GNPAT_HUMAN
Sequence: MESSSSSNSYFSVGPTSPSAVVLLYSKELKKWDEFEDILEERRHVSDLKFAMKCYTPLVYKGITPCKPIDIKCSVLNSEEIHYVIKQLSKESLQSVDVLREEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVNEEGIQKLQRAIQEHPVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNGYAPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDPVSLRSLAAGRMSRSSYNLVPRYIPQKQSEDMHAFVTEVAYKMELLQIENMVLSPWTLIVAVLLQNRPSMDFDALVEKTLWLKGLTQAFGGFLIWPDNKPAEEVVPASILLHSNIASLVKDQVILKVDSGDSEVVDGLMLQHITLLMCSAYRNQLLNIFVRPSLVAVALQMTPGFRKEDVYSCFRFLRDVFADEFIFLPGNTLKDFEEGCYLLCKSEAIQVTTKDILVTEKGNTVLEFLVGLFKPFVESYQIICKYLLSEEEDHFSEEQYLAAVRKFTSQLLDQGTSQCYDVLSSDVQKNALAACVRLGVVEKKKINNNCIFNVNEPATTKLEEMLGCKTPIGKPATAKL
What is the function of this protein?
Dihydroxyacetonephosphate acyltransferase involved in plasmalogen biosynthesis.
What are the official names of this protein?
Dihydroxyacetone phosphate acyltransferase, DAP-AT, DHAP-AT, Acyl-CoA:dihydroxyacetonephosphateacyltransferase, Glycerone-phosphate O-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.