PharMolix/UniProtQA huggingface dataset:
Protein: RLMH_RUEPO
Sequence: MRVSILAVGRLRTGPEKSLIDDYLTRFDRTGRALGLGPARVVEVEDKKNAGMGAEAALLRKALPAGAVLCTLDERGKQLSSPDFADRMAGWRDTGRQDLALVIGGADGIDPSLRAEADFSISFGAMVWPHMLVRVMLAEQLYRAATILAGSPYHRV
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_MYCS5
Sequence: MTQAVEYKGLGRRKSSVARVIIRPGKGEFHINKRPAREYLTSDLYLKDANQPFVLTETFQKFDTFVNVKGGGLNGQAGAIRLGIARALLHASPDYRTKLKAEGMLTRDARIKERKKPGLRAARRARQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: KTR1_YEAST
Sequence: MAKIMIPASKQPVYKKLGLLLVAVFTVYVFFHGAQYARGSAPSPKYSTVLSSGSGYKYSKVELPKYTGPREKATFVTLVRNRDLYSLAESIKSVEDRFNSKFNYDWVFLNDEEFTDEFKNVTSALVSGTTKYGVIPKEHWSFPEWIDEEKAAQVRKEMGEKRIIYGDSISYRHMCRFESGFFYRHPLMDDYDWYWRVEPDIKLHCDIDYDVFKFMKDNKKKYAFAISIKEYEATIPTLWETTRKFMEAHPELIHENNMLDFVSDDQGLSYNLCHFWSNFEIAALDLWRSPAYSAYFDYLDREGGFFYERWGDAPVHSIGAALFLDRSEIHHFGDIGYYHVPFHSCPIDTSIRLANKCDCDPSKDFTWHSYSCTTKFYNINKLPKPAGWQNHIG
What is the function of this protein?
Mannosyltransferase that transfers a mannose residue from GDP-mannose to a range of acceptors in vitro, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
What are the official names of this protein?
Alpha-1,2 mannosyltransferase KTR1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 15 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: SPL16_ARATH
Sequence: MGELPKDDWQMNRWKWDGQRFEAIELQGESLQLSNKKGLDLNLPCGFNDVEGTPVDLTRPSKKVRSGSPGSGGGGGGNYPKCQVDNCKEDLSIAKDYHRRHKVCEVHSKATKALVGKQMQRFCQQCSRFHLLSEFDEGKRSCRRRLDGHNRRRRKTQPDAITSQVVALENRDNTSNNTNMDVMALLTALVCAQGRNEATTNGSPGVPQREQLLQILNKIKALPLPMNLTSKLNNIGILARKNPEQPSPMNPQNSMNGASSPSTMDLLAALSASLGSSAPEAIAFLSQGGFGNKESNDRTKLTSSDHSATTSLEKKTLEFPSFGGGERTSSTNHSPSQYSDSRGQDTRSSLSLQLFTSSPEEESRPKVASSTKYYSSASSNPVEDRSPSSSPVMQELFPLHTSPETRRYNNYKDTSTSPRTSCLPLELFGASNRGATANPNYNVLRHQSGYASSGSDYSPPSLNSNAQERTGKISFKLFEKDPSQLPNTLRTEIFRWLSSFPSDMESFIRPGCVILSVYVAMSASAWEQLEENLLQRVRSLVQDSEFWSNSRFLVNAGRQLASHKHGRIRLSKSWRTLNLPELITVSPLAVVAGEETALIVRGRNLTNDGMRLRCAHMGNYASMEVTGREHRLTKVDELNVSSFQVQSASSVSLGRCFIELENGLRGDNFPLIIANATICKELNRLEEEFHPKDVIEEQIQNLDRPRSREEVLCFLNELGWLFQRKWTSDIHGEPDFSLPRFKFLLVCSVERDYCSLIRTVLDMMVERNLGKDGLLNKESLDMLADIQLLNRAIKRRNTKMAETLIHYSVNPSTRNFIFLPSIAGPGDITPLHLAASTSSSDDMIDALTNDPQEIGLSCWNTLVDATGQTPFSYAAMRDNHSYNTLVARKLADKRNGQISLNIENGIDQIGLSKRLSSELKRSCNTCASVALKYQRKVSGSRRLFPTPIIHSMLAVATVCVCVCVFMHAFPMVRQGSHFSWGGLDYGSI
What is the function of this protein?
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'.
What are the official names of this protein?
Squamosa promoter-binding-like protein 16, SPL1-related protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADA_DEHMC
Sequence: MYRELISHKIAELKKERKAIILAHNYQLGEIQDAADFVGDSLELARKAAKVDAEVIVFCGVHFMAETAAILSPEKIVLAPEPRAGCPMADMISGAELREFKSRHPGLPVVCYVNSTAEVKAESDICCTSANAVKVVESLKSDTVLFVPDQYLGAFVKERTSKKIISWPGYCPSHARIKPEDIVNLKKHYPAAKVIVHPESRPEVTALADEVLSTGQMVSYAARADVKELIVGTEIGMIYRLRKENPDKLFIPVSEQAVCANMKMTTLPKLLASLENMQAVVSVPEEIRVKAVGAVERMLRVV
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REM11_ARATH
Sequence: MAWNLAIITLVGKDGTKLEATLRRENRGLMCLGNGWKDLSISNGLKSGKSFTLELILENGTPMLSLVSTQSTSHKSQKRECSKHSEKESISAVPSKGKKNRKARSNREERRDSSSAIQNRFVTFTPEDIRDCILILPSQFIKANGINNLGEITLLGQNRMKWFAYLLSMSKDGSLALGSGWKGICEANGVNTGEAFTLEYIDEQETAHGRAQVCFYGVFPGKSVRSFASLRSKWNDLFYDFLREQNLRVNPIIGVAICLCKHHYCNYNSCSLFKPRPKLSQKNLNS
What are the official names of this protein?
B3 domain-containing protein REM11, Protein REPRODUCTIVE MERISTEM 11.
What are the subcellular locations of this protein?
Nucleus.
Protein: HMGR_ASPFU
Sequence: MEIRRPSRHGNHPDRTYQRTYKACISCRQRKAKCDLGTGPDGLPLGPPCAKCRREQKPCLFDEKRAWERVKKRGTQSTSNLANSMMRTVVSSGNDALNILFEAANAQSQEDSMIESDSLPETEQHRSGHPVTSEGSSNQIDLTVPPDVLEKAMRPVELSHVSKDVLSTWEACRFVRMGWFTAREAVTFIDLFFKNMSILSPVLTDFYADHKNHRWLIAHDPVLCCTILMISSRYHVLPGVGGQSRNFFIHHRLWQHCQQLVTRLIFGQELSSQPKIRNIGTIEALLLMSDWHPRSLHFPPESDGWDSDLVTIDLESTEYGDDGSNSSAKRWAKDMSEPAKRSDQMSWMLLGSALSLAHELGIYETGDKARDAFVAYERFMTKDQMRLRRQRAQRLLYVYINQLAWRIGCVSLMPQGLSHSILNRQTSRELSQYGEEWLTFMDSWMDLTKLAKSVTDMFFPSVTFARQQLQSGRYIDLLDHFRPLLDKWKERYLQPQLHDKPFYDDIFIEYHFVRVYTHSVGMQAVVERAIADGNADEEEVRPMNIDPIDYEYIQEVIDGCCQILEKVTQLADIGALRFSPVRIFVRITSASIFLMKALSLGARQAKLRESLDVLERTIQALRSNALDDIHLSTRYATLLETHVSRLRRHLVASCKSLKRRRESTTRHSMVPPSYASATSDEHAPLITNPPVPQNMSDMGFTPSLNDIAADDWLSLPFDPSMAPFSISSGGQFPAYEGGGLNFLWNLPS
What is the function of this protein?
Transcription factor; part of the L-tyrosine degradation gene cluster that mediates the biosynthesis of the brownish pigment pyomelanin as an alternative melanin (PubMed:19028908, PubMed:22046314).  Acts as a transcriptional activator for the genes of the tyrosine degradation cluster (PubMed:22046314).
What are the official names of this protein?
Transcription factor hmgR, L-tyrosine degradation gene cluster protein hmgR, Pyomelanin biosynthesis cluster protein hmgR.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTPRF_DANRE
Sequence: MVPNTCTSVPLLPVGLPLLLLLSCIQFSSQADSLPNFVRSPEDQTGISGGVASFVCQAAGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSLGEINTSAKLTVLEENQIPHGFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGRIKQLRSGALQIENSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELTNIRQSTNYTCVAISSLGMIEATAQVSVKALPKPPTSLTVTETTATSVTLTWDSGNPEPVSYYIIQYRAKTSDTNFQEVDGVATTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDAPLSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWLWPVQDPIIKYELQYWEADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTVSYQAVNGEDTERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQWKIEESTEYEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMIISTTVGNTALIQWQPPKDMVGELMGYRLRYKRLEEENYEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNGRIIHYIVVYRDINSKQNSTNRTSDTQMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAFATSFGVKAVMKTSVLLTWEVPENYKSQVPFKILYNQQSVEVQGNLKRKLITRLQPDTDYSFVLMSRGNSAGGLQQQVSIRTAPDLFKTKPVLYTADQTNNGKLTINLPKVPTSAPVRCYYIVVVPVSQTSSRQWINPDEMELDELLESSEGAHLRRRRRHTDTVRPYIAAKLSTLPETFTLGDELDYSGFINRPLPNNQHFQCFVMAELKDQYPVTANEKQRTFSASPYSDPIIVQGENQMQRSVDQPEMLWVMGPVLAVVLIIIIVIAILLFKRKRASPLPKDDHSGGVKDCLLASSSDPVEMRRLNYQTPGMREHPPISVSELADHIERLKANDALRFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINSNYIDGYRKQNAYIATQGPLPETLSDFWRMIWEQRASTIVMMTRLEEKSRVKCDQYWPIRGTETYGMIQVTMLDAVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARNLYAHIQKLTQPSAGETVTAMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT
What is the function of this protein?
The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase F.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL36_CHLT2
Sequence: MRVSSSIKADPSKGDKLVRRKGRLYVINKKDPNRKQRQAGPARKK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: MGST_DICDI
Sequence: MPFDTKSIFPDFIVFPSAISTIAIGLWSVQAYKLGEARKRYNVKAPHVQGDPEFERIAHEYQNTSEALGAIIPATFMFSYYISPKCSLLLGGTWLVSKMLNCCSYCCKKEKENDCAKNVHTCLSHISFFALLGGSAFGIGSSLYNRYKL
What is the function of this protein?
May perform the conjugation of reduced glutathione to electrophiles.
What are the official names of this protein?
Probable microsomal glutathione S-transferase.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HIK2_SYNY3
Sequence: MAGSISSMYSPSAGLISLCQSQVRLLQQGLRVDWCGVYLNQEETEQGLVPLVVSHGSTLVESESYGLISLPQGEVSPPMDDFSLPAVPVGVGQLSRRSRLEPPPFDADKRLVLPLVYGEEMVGLLVIHRSQGQWHGEEMMQLEAIAKSLAVACLLDQQQDWYRQAWEEQNQQYQWERQHWADLLHQLRNPLTALKTFSKLLLKRWHGDNKSQQVVEGIVRQGEHLQELLQSFEASQSQGPEAVPLLSSSPVTTIQVLPPADRVETMPLANFSLGEVLPPILLAHQAIAAERNITLTAQIALIDTVVMANRLALREVVNNLLDNGIKYTPNGGLVEVSLALEKVSSSGMDWATLAIADTGYGIPPEDQQKIFERNYRGVQGRGSINGTGLGLAIVADLVAQMGGKITVTSPNGLSRDPDQPGSTFTLWLRSGEQV
What is the function of this protein?
Member of possibly 2 two-component regulatory system(s) Hik2/Rre1 and Hik2/RppA.  Transduces PQ (plastoquinone) redox signals to photosystem gene expression machinery during the adjustment of photosystem stoichiometry.  Reduced PQ suppresses its autophosphorylation activity (i. e.  kinase activity is higher under oxidizing conditions) (Probable).  Member of two-component regulatory system Hik2/Rre1, controls expression of sigB (sll0306), sll0528, slr1119, slr0852 and ssr3188 in response to hyperosmotic stress (Probable).  Activity responds to high salt (with a linear response as concentrations rise to 0. 5 M NaCl); detects Cl(-) levels (PubMed:24283389).  Autophosphorylates and transfers phosphate to Rre1 (PubMed:25714549, PubMed:26904089).  May transfer phosphate to RppA in a possible Hik2/RppA two-component system (Probable).
What are the official names of this protein?
Sensor histidine kinase Hik2, CSK.
What is the protein family that this protein belongs to?
Belongs to the chloroplast sensor kinase protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_CORGB
Sequence: MLHIADKTFDSHLIMGTGGATSQALLEESLVASGTQLTTVAMRRHQATTSSGESIFAMLRRLEIALLPNTAGCRTARDAVLTAQLAREALDTNWVKVEVIADEHTLLPDTVELLDACELLVHDGFTVLAYTSDDPITASRLEDCGVAAVMPLGSPIGTGLGILNPHNIELICSRASVPVILDAGVGTASDATLAMELGCDGVLLASAINRAQNPVAMAKSMFHAVEAGRLAAQAGRIPQRQHAVASSSFEGLASWAEQVL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP79_YEAST
Sequence: MSTPFGLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGFGPRNRYLGESGKTKQTSNVKNTVENLKRIIGLKFKDPEFDIENKFFTSKLVQLKNGKVGVEVEFGGKTHVFSATQLTAMFIDKVKHTVQEETKSSITDVCLAVPVWYSEEQRYNIADAARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEEKPRIIGLVDIGHSTYTCSIMAFRKGEMKVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRKNPKAYNRILIAAEKLKKVLSANTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITNALAQAKLTVNDIDFVEIIGGTTRIPVLKKSISDVFGKPLSSTLNQDEAVAKGAAFICAIHSPTLRVRPFKFEDIDPYSVSYTWDKQVDDEDRLEVFPANSSYPSTKLITLHRTGDFSMKAVYTHPSKLPKGTSTTIAKWSFTGVKVPKDQDFIPVKVKLRCDPSGLHIIENAYTTEDITVQEPVPLPEDAPEDAEPQFKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAETEDRKNALEEYIYTLRAKLDDEYSDFASDAEKEKLKNMLATTENWLYGDGDDSTKAKYIAKYEELASLGNIIRGRYLAKEEEKRQALRANQETSKMNDIAEKLAEQRRARAASDDSDDNNDENMDLD
What is the function of this protein?
Has a calcium-dependent calmodulin-binding activity.
What are the official names of this protein?
Heat shock protein homolog SSE2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ATPL_ACIBS
Sequence: MELTLGLVAIASAILIAFGALGTAIGFGLLGGRFLEAVARQPELAPQLQTRMFLIAGLLDAVPMIGVGIGLFFIFANPFVG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCY_AZOVD
Sequence: MSVRPVVITIDGPSGSGKGTVAGLLAKRLGWNLLDSGALYRLLAFAARNHGVDLTNEEALKVLAAHLDVQFVTSTDLHPQQIILEGEDVTDAIRNEQVGAGASQVASLPAVREALLQRQHAFLEPPGLVADGRDMGTVVFPDAPLKVFLTARAEERARRRYQQLKESGVDANLSSLLGEISKRDERDSQRAVAPLKAAPDAIQLDSTELTIEQVVERIMSEIAARDLAG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_COXBR
Sequence: MSGGVKLIAGLGNPGDQYARTRHNVGAWFLETLAQQRNQSLAKENKFHGFVAKCNDYWLLKPTTFMNESGQAVAALAHFYKIKPSEILIAHDELDFPAGDIRLKEGGGHGGHNGLRNIIQHLGSSDFYRLRIGINHPGHKDRVTPYVLSPPSENDRIAILAAIEKGLRLIPELVQGDFQKVMRELHS
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_ECO27
Sequence: MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLALMREMTHAGELEHLTPERVWKETENALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPARWHPEIDTGIHTLMTLSMVAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAVASWKEQRCPKPD
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RNZ_BACCZ
Sequence: MEFVFLGTGAGVPSKGRNVSAIALQLLEERGQTWLFDCGEATQHQILHTSVRPRRIEKIFITHLHGDHIFGLPGLLGSRSFQGGTTPLTVYGPKGIKQFIEVALSVSTTHVKYPLEIVEITEEGTVFEDNEFHVETKRLSHGIECFGYRIIEKDIQGALLVDKLLEMGVKPGPLFKRLKDGEVVELENGTILNGKDFIGPPQKGRVITILGDTRYCEASRELAQDADVLVHEATFAAEDEQQAYDYFHSTSKQAASIALQANAKRLILTHISSRYQGDTYKELLKEARELFSNTEIATDLKSFPVDR
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: PRP5_PHANO
Sequence: MHGHRASASAIHPDYPVTHRESTWRRATLIVQGSTATVDDTLRPAVPARGLQAAEIAREIATEIATAVAEVVTTVTVLEIDVTTAETTAAMTVETTAETAAAHVHHPVARGHRTAEMIVTAETTAGTTAGTTVAMIGTGVEVPRHVGQARDVLQPHRPRTSAATREERVNPEKQKEDKLAERAAKLLEWKKRKEAERLAQEKAGTPGSGASPAGSVPSTPAVAATPPPREAKPTVAKSKVPKPATEKVKQKQPEKSSFKLDESAAARPLIAKPAGKPVAIAAASKYHHIDYKCSNQLTQTDGAAAAATTKANGNIGSFGLKTKSTAEEDISSKALLDDEIDTGKRKLQALPVFATHDEPETTAGVEDDAAMSDIGTDDDETNAQLQAKLQSRRAELSHDQAADKDTNMEEVPTADNTGDQMDVDDNAGAEEDDVDPLDAFMADLSVPQQPSRAAPQGETMFNDDLEPEQTAVEGEDLLALRAAKKKKKEVPTINHEKVEYEPFRKDFYTEPAEITQMSAEDVADLRHELDGIKVKPDDVPRPVTKWAQMGLLQQTMDVFTRVGYARPTAIQAQAIPIAESGRDLIGVAKTGSGKTLAFGIPMIRHVLDQRPLKPADGPIGLILAPTRELSLQIVNELKPFLNASGITIKCAYGGQPISDQIAMIKRGGIHILCATAGRLIDLLQSNSGRVLSFRRITYVVLDEADRMFDMGFEPQVMKILASIRPDRQTILFSATFPKTMAALARKALDKPAEVIIGGRSKVAPEITQHITIVPPSYEKKIAKLLHHLGQTFSDDENAQVLIFTERQETAEDLLSKLFKAKYFAVNTIHGAKDQTDRNEAINEFKQGLLNILIATSVAARGLDVPGLALVYNFDCPTHLEDYVHRCGRTGRAGNKGLAVTLIENPGQERFAVHIVKALKESGAEVPDDLQAMANAFHEKVKSGTEKYYNVGFKGKGLDELDASRALDKKREKRALKLGDDDASDDEPDLPKLKKPEASGPGVAKSTNGDAAAEPVQDEPAWKKLLLGKIVVNKTERAETGKPTTAKERAMAAARKIDGNLSRKGTVHAGQPIDNKGPDAGLYHSTLEINDFPQKARWAVTNRTNVAKILDATGVSITTKGNFYGPGKEPGETDLPKLYILVEGDTEGVVTQAMLELTRLLTDATVAAEEAASTRGPTGRYSVMS
What is the function of this protein?
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing.  Catalyzes an ATP-dependent conformational change of U2 snRNP.  Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase PRP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLSX_SALTI
Sequence: MTRLTLALDVMGGDFGPSVTVPAALQALNANSQLTLLLVGNPDIITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGTSMRVALELVKEGRAEACVSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQFAVMGAVLAEEVVGIKNPRVALLNIGEEETKGLDSIREASLMLKTVPTINYIGYLEANELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKSLTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAARLESVYPAGFEPLDDGKGVNLRAHR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RANB9_XENLA
Sequence: MSSPPLHGLSSVGHLSRDPPPRSWSPRDKCSYLGLSHGNLRVHYKGHGKTSKDAASVRSTHPIPAACGIFYFEVKIISKGRDGYMGIGLSTQGVNLNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLIDNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDANFGQSPFVFDIEDYIREWRSKIQAQIERFPVAGEWQSMIQRMVSSYLVHHGYCSTAEAFAKSTDQTVQEELASIKNRQRIQKLVLSGRMGEAIETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGNRSLKSPDGCLGSDSNCSNGIISNKAHQTHCHSKSQSSNLNVTELNSINMTMSHQLNSYSSNDVEMETDHYSNGFSASTSNGFLNGSSRHEPELEECDTEMEVDTSHGRRQLCGGSQAAVERMICFGRELQAMSEQLRRERGKNATNKNMLKDAFSLLAYSDPWNSPVGYQLDPIQREHVCSSLNSAILDIHNLPKQPPLSLALEQASQCLEMMAQCGIGSCAFARVADYLH
What is the function of this protein?
May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways.  Acts as a mediator of cell spreading and actin cytoskeleton rearrangement.  Core component of the CTLH E3 ubiquitin-protein ligase complex that mediates ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ran-binding protein 9, RanBP9, Ran-binding protein M, RanBPM.
What is the protein family that this protein belongs to?
Belongs to the RANBP9/10 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Note=Predominantly cytoplasmic.
Protein: DHCR7_HUMAN
Sequence: MAAKSQPNIPKAKSLDGVTNDRTASQGQWGRAWEVDWFSLASVIFLLLFAPFIVYYFIMACDQYSCALTGPVVDIVTGHARLSDIWAKTPPITRKAAQLYTLWVTFQVLLYTSLPDFCHKFLPGYVGGIQEGAVTPAGVVNKYQINGLQAWLLTHLLWFANAHLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMVKGYFFPTSARDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQRELHSHVTNAMVLVNVLQAIYVIDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPHAVGVLLLGLVGYYIFRVANHQKDLFRRTDGRCLIWGRKPKVIECSYTSADGQRHHSKLLVSGFWGVARHFNYVGDLMGSLAYCLACGGGHLLPYFYIIYMAILLTHRCLRDEHRCASKYGRDWERYTAAVPYRLLPGIF
What is the function of this protein?
7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in that pathway.
What are the official names of this protein?
7-dehydrocholesterol reductase, 7-DHC reductase, Delta7-sterol reductase, Sterol Delta(7)-reductase, Sterol reductase SR-2.
What is the protein family that this protein belongs to?
Belongs to the ERG4/ERG24 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ATPE_COXB1
Sequence: MAKTMQLEIVSAEAAIFSGKVEMIVVTGGMGELGIYPGHRQLLTSLKPGQIKAILEGGKEEVFYMSGGMLEVQPEIVTILADTALRAVDLDEAAAISAKEEAERRLAKQKAGIEYSKAMTELAEAAAQLRAIQMLRKSAKKH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1840_STAHJ
Sequence: MPKQSKMSNVAYEQLNQDADRILHLIKVQMDNLTLPSCPLYEEVLDTQMFGLQKEVDFAVKLGLVDKEDGKNLMLRLEKELSKLHEAFTNVK
What are the official names of this protein?
UPF0358 protein SH1840.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: DPH2_SCHPO
Sequence: MSFELSAPVPLSDNSEAILEKEIGETVKIEGDLVEVYEINRTVDFIKSGNYNSVALQFPDEHLADSGKVASILTNLVEANVQILADTNYGSCCVDEVAAEHMSADAIVHYGRACLSPTSRLPVLYVFGRLPINLHKLEKCLTIPLDQNILLVSDTRWYYAQDSILKSLKTLGYQNVYESHLKERIEPNLEEASTSYTIPGRTYSLPKSLSLQDMTLLYIGPDSPTLSSILMSHYSLVNQFLSFDPLSNKIVEESSFTGAKLRRRYALVQRCRDAGVIGIVIGTLGVHRYLHVLNQLRKMILNAGKKPYMLAVGKLNPAKLANFQEIECFVLIACGENSLIDSKEFYRPIVTPFELVKALSSDMSWNNDFILSFDEVLKLSEGKQSKEPSEVLTEESAEPHFSLITGKFVNSTPMRHLDVTLETADAKNNDSSSASIEKRGMRSLAVNGVYSPAAAFLQSKSWSGLDSVDEGEGPSKLYEGQSGIAKGYVGEGSKEKIQRDFGK
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase, predominantly cbr1 (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the dph1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.