PharMolix/UniProtQA huggingface dataset:
Protein: RS14Z_LACDB
Sequence: MAKTSQKVRNHRPAKFSSREYTRCERCGRPHSVYRKFGLCRICLKELGHKGQIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: YCIB_SALDC
Sequence: MKQFLDFLPLVVFFAFYKLYDIYAATSALIVATAIVLIYSWVRYRKIEKMALITFVLVAVFGGLTLFFHNDEFIKWKVTVIYALFAGALLISQWVMKKPLIQRMLGKELALPQQVWSKLNLAWALFFIVCGLANIYIAFWLPQNIWVNFKVFGLTALTLIFTLLSGVYIYRHLPQEDKS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NTE1_PICST
Sequence: MKDSTEALNSIAFAVDTTLSSILPSSLAPPSAPPATSSFLKSIWYAFWWLWSMVVFKIMNIILLYIPSKIMNALSINFEITLNLSSILVALSAIITVCFLVVRYKYLTGYSKDTSDRKTKGKVNPSASNINLKNQSLDYVDQKKGHRRTTNYLDEFLSAIKVFGYLEKSVFHELTKNMTTQKLSHDEILYLDEKLGFSIVVEGVMQVYTRITENSNVSGGFDPDDDNELNYEKDDVLIIGNQRYQLLNEVKSGAPLSSLVSVLDLLKPVDSEDSTSDMLHSFNISDDDNISKIPEISPISLPFQGIHAGAKDDSVPPSPIIRPSKTKQLYPEIVARPKSRPHKEHTGHHLHHVHHSGATIAIIPYSAFQRVQSKYPKATSHIVTMVLARLYKVTFNTIHDYLGLTKEIMESEVKLNTTSSVRGANLPGYLFDGLLDKIYGANGINEASLSRKSDFQRASSVNLNKQKTTLCDAKSSRYVLLDSRLKSTHPGDLLSSVPLSRRSDYYQTHSHPLSADDPLVRSAFPSSKTLSSLSSPTSNLKRASSNLKFENIRDRSFSDDREETEETSLRIAVVESIFKILGISEKSTAMRNLSSFNSGRSSVSSSIVGLSNLMSADDKFDTNAARVRFDSYNGFSSTATSISRSSTPIKFYNTINQNQLHNHHMGDSVSGINISTLSRQHQANRNSSPTEFNFANVKSDFAKCLEIKSYGPNTTIVEQGSFNSGLYYVIDGSLDVLYRPSNHGEPSSNREDNLKKLYSVKSGGVAGYLSSVVGFRSLVTIRTSKKRGVIVAHISKSDYSKLMDRYYFLQLPVATKLKKLLSPQILTIDYALEWCHIPAGGVLCSQGDLANGFHIVLSGRFRVVRNKSDRYQGNTSDDDILGFSDTSMDCSPSSDINNEDLEVLGEYGHGESIGEVEVLTASRRTNSLIAVRDSETARIPRTLFEMLSLSNPSIMVKVSRIVASKVVYKDVLDQSSRNSTLIPSSTASHISNDYKTITILPTVSGLPVREFADKLVSALKAIGRNVIALDQASTLTHLGRHAFDERLAQLKLSGYFAYLEEEYETIVYICDTPLKSNWTSTCISQGDCILLLADAEDDVVATGIGDYERLLINLKTMARTDLCLLHPEKYVEPGSTSIWLKNRIWVQGHHHIEMEIIRKKDENSVKKRPNIISELASKIGSKTNPSIKSTLEDVRLKAISSFVKLNTSFVHSDRYKAVQPHKNDFLRLARILSNEAVGLVLGGGGSRGISHVGIVTALERHGIPVDLIGGTSIGSLVGGLYAKDYNIVSIYGRAKKFSKRVASLWRSVFDLTYPVTSYITGYEFNRGIWKIFGFTEIEDFWIRYFCNTTNITNSTMDIHESGYSWRFIRASMSLAGLLPPIAFQGCMLLDGGYLDNLPVSEMKKKGAKYIIAVDVGSADDRTPMNYGDTLSGFWVLFNRWNPFSKHPNVPNMMDIQMRLAYVASVNALEAAKKTNGVIYLRPPIDNYATLDFAKFDEIYHVGLNYADKLFSSWSKNGKLPAIAGMVDKAKIKSGDDKKVLYRRNSI
What is the function of this protein?
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho).  Plays an important role in membrane lipid homeostasis.  Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
What are the official names of this protein?
Lysophospholipase NTE1, Intracellular phospholipase B, Neuropathy target esterase homolog.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YHJC_BACSU
Sequence: MKLIHVLAALPFIGILLGIPFANKVTPYVFGMPFILAYIVMWALLTSALMAIVYVLDKENKKEEAE
What are the official names of this protein?
Uncharacterized membrane protein YhjC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RCF1_PICGU
Sequence: MDIIQKMVFKSKQQPLVPIGALATTGAIILASKSIRRGDRIKTQIYFRYRIGFQLLTLVALVAGGLYYQTETAQQKQTREEKLRDKAKLREKLWIEELERRDAVIQERKKRLEESKAELLEVAQQGFEEARETETREAQLKKEEIEEKEN
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: HLDE_SALA4
Sequence: MKVNLPAFERAGVMVVGDVMLDRYWYGPTCRISPEAPVPVVKVNTVEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKTLAEVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALGSIGALVLSDYAKGALTSVQTMISLARQAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVAGKCKSEDELVERGMKLIADYDLSALLVTRSEQGMTLLQPNKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNTLEEACYFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELRQAVASARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGESRPVNPLEQRMIVLGALESVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSEEVWANGGEVMVLNFEDGCSTTNIIKKIQTESEK
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: ENO_DEHMB
Sequence: MSAVVKSIKAREILDSRGNPTVEADVVLSDGSFGRAAVPSGASTGSHEAVELRDGDKSRYNGLGVHKAVANVNTTIASAISGFKASDQQRLDNLLIELDGTPNKAKLGANAMLATSLAVAHAAAASRHMPLYRYLNNSEEYILPVPMFNILNGGKHASNSTDFQEFMVMPVGAKSFAQALQMGTEVYHSLKKVLKGMNQNTTVGDEGGFAPSLPTNKDAVEVILKAIEKAGYRPGEDIFIALDPASSELYQDGKYTLATENKTLSSAEMVDYWCGWVEKYPIISIEDGLFEDDWDGWKLLTRKIGNKVQLVGDDFYVTNIKRLDRGIKEKASNSILIKLNQIGTLSETIAAIKMANNAGWTAVVSHRSGETEDTTIADLAVAMNAGQIKTGAPCRSERTAKYNRLLRIEEELGGKAKYPGKDAFLNLK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TRUD_PSEMY
Sequence: MNELQLLGPRAHGEACGRAVLKASAEDFQVDEVLDIPLTGQGEHLWLWVEKRGLNTEEAARRIARAAGLPLKAVSYAGLKDRQALTRQWFSLHLPGKADPDLAAAQGDDLAILRSQRHNRKLQRGAHAANGFTLRLTALEADRDALEQRLQRIAEQGVPNYFGLQRFGFDGGNVVQARDFAARQELPVQRNLRSRLLSAARSHLFNQVLARRVAAGTWNQAQIGDLLAFTGSRSFFLAGEAECGDPRLAILDLHPTGPLWGDGPLPTGGATQMLEQSVADEAGQLVDWLVKADMAHERRILRLPIGGLSWHYPEPDILQLAFVLPAGCFATVVVRELLDLVPAGQTDTPCEF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: SPC25_ASHGO
Sequence: MSLEGFAELRAQMEAFQGRVHGHLGQQRHAMEQLLAAHRQEVEKLRLRTGAVQQQLARLAGEEQELRQNISSLQERTQHTTAQRDAYAAQRQKLAAERTQLEHDRAELHAMLARKQAELQRQREAIKRQHMRDNPEVRVYEQLLGLYVRASRPDSLEFAFRNVSEADARAECSFTLDLGADGYRVAAAQPPLPLERLRDLERDLGSSGDLPAFLKAIRAALVTAMAGQADA
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein SPC25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: PSBK_EUGMY
Sequence: MLNLNFTNITVMGILPEAYAPFDPIVDILPIIPILFFLLAFVWQAAVKFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ATPB_CORU7
Sequence: MTTAIQEQQNSAAPTAAGRVVRVIGPVVDVEFPRGQQPALFNALHVEVDLEAVAKTITLEVAQHLGDNLVRTVSMAPTDGLVRGAEVKDTGKPISVPVGDVVKGHVFNALGDCLDEPGLGRDGEQWGIHREPPAFDELEGKTEILETGVKVIDLLTPYVKGGKIGLFGGAGVGKTVLIQEMITRIAREFSGTSVFAGVGERTREGTDLFLEMEEMGVLQDTALVFGQMDEPPGVRMRVALSGLTMAEYFRDVQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGVLQERITSTKGKSITSLQAVYVPADDYTDPAPATTFAHLDATTELDRAIASKGIYPAVNPLTSTSRILEPGIVGEKHYEVAQRVINILQKNKELQDIIAILGMDELSEEDKITVQRARRIERFLGQNFFVAEKFTGIPGSFVPLEETIDAFERICDGEFDAYPEQAFNGLGGLDDVEAAYKKLTDK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MDH_SULAC
Sequence: MVKVAFIGVGRVGQTIAYNTIVNGYADEVMLYDVVPELPEKFEHEIRHALAALRVKTELLSTNNIDDISGADIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKNKGAMYIMVANPVDMMASVFMKYSGENTISTGNQVETMRMRSYIAKKLNIPAYEVGGYVGGEHGEAAMVLWSTVTVKGKPFSESLGVNKAEVEDYVKKIAAEIIRVLGGTTWGPGADIEEVIRSVALNEGKVMSVAFPHKYEDEIIHISEPVVVGRTVGPALTSALDENDKARLSQAIKEVYNVYKSNLKELEQVIS
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: TRPF_NEIM0
Sequence: MRKIRTKICGITTLEDAAAAAAAGADAVGLVFFQGSSRAVDIARAKKITAALPPFVSVVALFVNESAQNIRRILAEVPIHIIQFHGDEDDAFCRQFDRPYIKAIRVQTASDIRNAADRFPDAQALLFDAYHPSEYGGTGHRFDWTLLAEYSGKPWVLAGGLTPENVGEAVRITGAEAVDVSGGVEASKGKKDPAKVAAFIATANRLSR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: PURA_CLOAB
Sequence: MSAFIVLGAQWGDEGKGKMTDYLAQGADVVVRFQGGNNAGHTVEVEDKKYKLHLIPSGILYKNKVNVIGNGVVLDPKAMFEEVEYLKGMGVEVTPENLIVSDRAHLIMPYHRALDGASEKHRGKNDIGTTGKGIGPCYTDKAERSGIRVCDLLHPEVFKEKLKSNLEIKNAIITKVYGMDAFDYNEICEEYLAFGEKLKPFVKDTSVIVYNEIKNGKKVLFEGAQGNLLDIDYGTYPYVTSSNTIGGGVCPGAAIGPTMITSAVGIAKAYTTRVGKGPFPTELLDEMGDRIREAGFEYGVTTGRARRCGWLDTVILKQAARVSGLTSFAMTKIDTLAGIDKVKVCIGYDFNGKTIDYIPASLEDLALCKPIYEEFDGWDESVADARSYDELPLNAKKYLKRIEELTETKISIVSVGPERNHTIEVSDI
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_SHEON
Sequence: MLDLLPDLFDHYPSKLTLLPLAFRAFGGKRLFWGEVVTVKCFEDNSKVKEVLAQPGHGKVLIVDGGGSSRRALLGDLIAQSAMDNGWQGVIINGYVRDAARLSSFNLGVYALGAMPMKTEKLDQGQINVPIELGCVTVKPGMMVYVDENGIAISEESLNFAFLN
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: MNMG_DESRM
Sequence: MRYHAGDYDVIIVGAGHAGCEAGLAAARMGCKTLVLTLNLDNIALMPCNPAVGGPAKSHLVKEIDALGGQMGLTTDLAAIQMRMLNTGKGPAVYALRAQADKVKYQQLMKKNLETQENLDVKQLLVEEILVKNGRVTGVATQIGAEFSARAVVVTTGTYLKGRIIIGNVHFPGGPNSQFPSVNLSENLRSLGLELGRFKTGTPARVDRRTIDFTKMTIQPGDEEVHNFSYISPVTQREQVPCWLTYTTEKTHEIIRENLHRSPLYSGIIEGVGPRYCPSIEDKIVRFADKPQHQIFVEPEGLHTYEMYVQGMSTSLPPDVQLKMYRTIPGMENVSIMRPAYAIEYDYIVPTQLRTTLETKEIIGLYAAGQINGTSGYEEAAAQGIMAGINAALQVQEKDPFYLSRSEAYIGVLIDDLVVKGTNEPYRLMTARAEYRLLLRQDNADHRLTQKGYNIGLVSQVRYDHYMNKWQSISKEMERLKTIVIPANEETNKVLKSLESSEITQNTPFINLLRRPEIKYNTLAGLSDHFLDLPQEVIEEVEIEVKYEGYIKKQLAQVERFEKLEGRILNIDIDYEMIKGLSLEARQKLKKFKPTSIGQASRISGVSPADISVLLIWLEQERRKIAGGDA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXRD1_BOVIN
Sequence: MLRRALRLRLGPCLSGRGLGTYRRGSTLDWDGKVSEIKKKIQSIFPGGAWNPLYDTSHLPPERSDVVIVGGGVLGLSVAYWLKRLEKQQGAIRVLVVERDHTYARASTVLSVGGIRQQFSLPQNVQLSLFSAEFLRNINEYLAVVDDPPLDLQFNPSGYLLLASEEGAAIMERNVKMQRQEGAKVCLMSPEQLQKKFPWINTEGVALASYGLENEGWFDPWCLLQGLRRKLQSMGVLFCQGEVTRFISSSSHMETASGEQLTLKRIHEVHVKMDHSQEFQPVECAIVVNAAGAWSGQIAELAGVGNGPPGTMQGTKLPVEPRKRYVYLWHCPQGPGLEAPLVADPSGAYFRREGLGNNYVGSCSPTEEEEPDPGNLEVDYDFFQEKVWPRLAQRVPAFETLKVRSAWAGYYDYNTFDQNGVVGPHPLVVNMYFATGFSGHGLQQAPAVGRAVAEMVLEGHFQTINLSPFLFSRFYFGEKAQEHCIL
What is the function of this protein?
Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I).  Involved in mid-late stages of complex I assembly.
What are the official names of this protein?
FAD-dependent oxidoreductase domain-containing protein 1.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: F90A5_HUMAN
Sequence: MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTEPSDYLRVASGPMPVHTTSKRPRVDPVLADGSATEMSDRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE
What are the official names of this protein?
Putative protein FAM90A5P.
What is the protein family that this protein belongs to?
Belongs to the FAM90 family.
Protein: ERA_STRPG
Sequence: MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTLIKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKRDEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNEKEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: CYCO_CLITE
Sequence: GIPCGESCVFIPCITGIAGCSCKSKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide cter-O.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OXLA_TRIST
Sequence: MNVFFMFSLLFLAALGSCADDRNPLEECFRETDYEEFLEIARNGLKATSNPKHVVIVGAGMSGLSAAYVLAGAGHEVTVLEASERAGGRVRTYRNDEEGWYANLGPMRLPEKHRIVREYIRKFNLQLNEFSQENDNAWHFVKNIRKTVGEVKKDPGVLKYPVKPSEEGKSAEQLYEESLRKVEKELKRTNCSYILNKYDTYSTKEYLIKEGNLSPGAVDMIGDLMNEDAGYYVSFIESMKHDDIFAYEKRFDEIVDGMDKLPTSMYRAIEEKVHFNAQVIKIQKNAEEVTVTYHTPEKDTSFVTADYVIVCTTSRAARRIKFEPPLPLKKAHALRSVHYRSGTKIFLTCTKKFREDEGIHGGKSTTDLPSRFIYYPNHNFTSGVGVIIAYGIGDDANFFQALDLKDCGDIVINDLSLIHQLPREEIQTFCYPSMIQKWSLDKYAMGGITTFTPYQFQHFSEALTSHVDRIYFAGEYTAHAHGWIDSSIKSGLTAARDVNRASENPSGIHLSNDDEL
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme.  Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, antibacterial and antiparasitic activities, as well as regulation of platelet aggregation.  Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation.  These different effects are probably due to different experimental conditions (By similarity).  Displays dose-dependent inhibition on HIV-1 infection and replication (PubMed:12963032).
What are the official names of this protein?
L-amino-acid oxidase, LAAO, TSV-LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IL6_SPAAU
Sequence: MPSRLNVFWLCAAALAALLRCAPAAPVDGAFTDNPAGDTSGEEWETERPADPLIALLKVVLEVIKTHRQEFEAEFHIRYDVLAQYNIPSLPADCPSTNFSMEALLHRLLQGLPVYTALLKYVEKEEPKSQIPSRFRQNSELLKQRITGKMRHAVQVTPLTSSQEQQLLRDLDSSDTFHRKMTAHSILYQLRSFLVDCKNAINKKEKLRESRANRAMTPVTLYYQS
What is the function of this protein?
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism.  Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway.  The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'.  Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
What are the official names of this protein?
Interleukin-6, IL-6, sbIL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PXPA_YERP3
Sequence: MKIDLNADLGEGCANDQALLQLVSSANIACGFHAGDAQTMRQSVRWALEYGVAIGAHPSFPDRENFGRTAMQLPPETVYAQVVYQLGALAAIVQVEGGVMQHVKPHGMLYNQAAVDPLLADAIAQAVKAVDPSLRLVGLAGSELIRAGTRVGLVTRQEVFADRHYQPDGTLVPRSQPDALIESDELALSQTLAMVQQHQVQACDGSWVQVQADTVCVHGDGVQALAFARCLRDRFQQEGISVIAQ
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: FAAH_MEDTR
Sequence: MGKKRVMVPAKDVDLSSIKYEPEIVQAPHLTGFWFRFFVRLIEAPLIGPFLLTMLKKENKIDQLLRNTVFPEEPMFKPEYPPQEKEHSVVELDEDGRPEGRVESALNCLPHYDPAKLWENSSATFRYWKIRDYAYAYQSRKVTPSMVAESIISMIEENGIDKPPTPLLLSFDAAEVRKQAAASTQRFESGNPLSILDGIFIAIKDDIDCHPHPSTGGSTWMHEVRDVKKDAVCVSRLRSCGVIFIGKTNMHEFGMGTTGNNSNYGTARNPHAPDRYTGGSSSGPAAIVASGLCSAALGTDGGGSVRIPSSLCGVVGLKINYGRTSMEGSLCDSGTVEVIGPIASTVEDAMLVYAAMLGASPANRISMKPSTPCLPTLSSDDDTDALRSLRIGIYTPWFNNVHSTEVSDKCEDALNLLSKAHGCEVVEVVIPEIVEMRTAHLVSIGSECLSSLNPDIEDGKGVKLSYDTRTSLALFQSFTAADYVAAQCIRRRIMHYFMEIFKKVDVIVTPTTGMTAPRIPPSALKSGETDMPTTGYLMRFVVPANLLGLPAISVPVGYDKEGLPIGLQVIGRPWAEATILRVAAAVEKLCGESKRRPVTYYDVLGAN
What is the function of this protein?
Catalyzes the hydrolysis of bioactive endogenous fatty acid amides to their corresponding acids (PubMed:16624618).  The hydrolysis of endogenous amidated lipids terminates their participation as lipid mediators in various signaling systems (Probable).  Converts a wide range of N-acylethanolamines (NAEs) to their corresponding free fatty acids and ethanolamine (PubMed:16624618).
What are the official names of this protein?
Fatty acid amide hydrolase, N-acylethanolamine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Cell membrane.
Protein: MTNA_SORC5
Sequence: MFLLEQRELPERERYLTLTDSAGVAEAIRTMAVRGAPAIGIAAAYGMALAARAARDEGASSYVAAMRAAGEHLASTRPTAVNLGWAVRRAIAAALQNAGRRGEERARELAELAREIHREDVAACHQMGRAGAARLPESGTVLTHCNAGALATGGYGTALGVIRAAIEAGKALRVLACETRPYLQGARLTAWELQRDGIPVEVISDSMAAWFMQKGEIGAVVVGADRIARNGDVANKIGTYGLACLARHHGIPFYVAAPWSTIDLATDSGASIPIEERSRDELAVVGGRRVVPPGVPVRHPAFDVTPAELVTAVFTERGKLTTREISRSVPPAAPAG
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: YP108_YEAST
Sequence: MKEASDREEAPKMVEKNYSTGFRKAHGEKDQSVTKPISLDGRTGEVIVRKSTGKTKIRKGQTEEEYTQQLQHYFEVEQGPVRTKVGWMDEVDPLVEIREGKYDISNKHQRQVLSGFCHRLFYQCKYKECLDLSTYFLGLFEPFNVKNKMKRELEELEYMIERCRGHVL
What are the official names of this protein?
Uncharacterized protein YPL108W.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MU145_SCHPO
Sequence: MPIPKNRPMHVEEEVSSQTNTEILLFALVIILSVIFINFFFFYLCRCCVYFYHTLENQEGDDERPLIQHHMVNRSTGSLSPSVDRLGNVLGYDIPSRRRRSVVSKEALSCISLEIPYIKWLKKRKGHAKGESTFLDNRSENQSVIVQGQGETPSVIITYDVRRPNLGSTSFVEMSSALSNIYNTDASDGDSSDDSCLLEDEEDFCIICYADYAFDDILRVLPCEHVFHTQCIDTWMTTMKASCPLCNEDYYKYFLQMDAASSVTHENAAWSIPLSPGDSRTHSAETDRSLLSAMSVRNSRMPYIVSSTL
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
RING finger protein mug145, Meiotic expression up-regulated protein 34, Meiotically up-regulated gene 145 protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IDI_ECOBW
Sequence: MQTEHVILLNAQGVPTGTLEKYAAHTADTRLHLAFSSWLFNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRCRYELGVEITPPESIYPDFRYRATDPSGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHGIDATPWAFSPWMVMQATNREARKRLSAFTQLK
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.