PharMolix/UniProtQA huggingface dataset:
Protein: MT_THEVL
Sequence: MTTVTQMKCACPHCLCIVSLNDAIMVDGKPYCSEVCANGTCKENSGCGHAGCGCGSA
What is the function of this protein?
This protein complexes cadmium, zinc and copper.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 14 family.
Protein: VA0D2_RAT
Sequence: MLETAELYFNVDHGYLEGLVRGCKASLLTQQDYVNLVQCETLEDLKIHLQTTDYGNFLAHETNPLTVSKIDTEMRKKLCREFDYFRNHSLEPLSTFFTYMTCSYMIDNIILLMNGALQKKSVKEVLAKCHPLGRFTEMEAVNIAESASELFKAVLVETPLAPFFQDCMSENTLDELNIELLRNKLYKSYLEAFYKFCKDHGDVTAEVMCPILEFEADRRALIITLNSFGTELSKEDRETLFPTCGKLYPEGLRLLAQAEDFEHMKRVADNYGVYKPLFDAVGGSGGKTLEDVFYEREVQMNVLAFNRQFHYGVFYAYVKLKEQEMRNIVWIAECISQRHRTKINSYIPIL
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  May play a role in coupling of proton transport and ATP hydrolysis (By similarity).  Regulator of osteoclast fusion and bone formation (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit d 2, V-ATPase subunit d 2, Vacuolar proton pump subunit d 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: Y4TG_SINFN
Sequence: MLYGFTWDTGNGELAFAISILPMLLMGLITTLQAAFLGFFVACVLGMVFAVLRGMRTRWVAWPAAVLIEFIRDTPLIAQLFFLYYVLPEYGIIFPAFLTGALALGIQYSAYISEVYRGGIQAVDHGQREAAKSLDLPPARTFTHVILPQAIPRVIPALGNYLVSIMKDVPVLSVVTIVEMLNAAKIIGDQTFNYLVPLSMVGGIYLILTIVASALVRIVDVNLPKRGVPLR
What is the function of this protein?
Probably part of the binding-protein-dependent transport system y4tEFGH for an amino acid.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable amino-acid ABC transporter permease protein y4tG.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RHAM_ECODH
Sequence: MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKARNLLFAMVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFYLP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCCDC_DICDI
Sequence: MMKGHFCIQNNKTLLFKSLIHPTSSHNLSPYLYFFLSSNKLNSSNISSSNFVITSNIRGYSSSQYSNKVYSWGSGLNGKLGHGLDETKIVVPKEIEIKEDDDNNRVFNQGKINKITSGTTYSIFSGYDQIKDRQVFYGCGDNRDAQLIVGNGKIQSLENIELLESPMLKSDQMKGKQLKQLISGTYHNACILNDSNSNNNNNNNKDRSLILLWGASNSGQIGSPEYNRVQYDPYNNKVLSEIGIKKISMGATFTIALSNDGKLYSFGSSTFNELGNGDMFNEREPKLIDNQLLQDNEIIDLECGFFHTVALTSDNKILTWGRNQESQCFPVPEGTGKGSFTNVQYLDTSSLGDHDKIIQIGASNLNSYILTENGNIYSIGSNDHGQCGIEKSNFKKGILNKIKIGDDGNIKVKKFYSRFKTVIVETTDGRFFGWGSNFDHQLALETRCIYFTPMELNNLNRLHKDYNIIDISISLSHCISLNSNPQK
What are the official names of this protein?
RCC1 repeat-containing protein DDB_G0284033.
Protein: PETL_PHYAM
Sequence: MLTLTSYFGFLLAALTITSALFIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYL_RICM5
Sequence: MNQIEQKWQHIWQEEKAFEVSNASSKPKYYVLEMLPYPSGKIHVGHVRNYSIGDVIARFMTMQGFNVLHPMGWDAFGLPAENAAIKNNSHPKKWTYSNIENMKKQLKSMGFSYDWSREINSCDPEYYKHEQKFFLELYERNLAYQKESLVNWDPVDNTVLANEQVVDGRGWRSGAIVAKRYLKQWFLKITDYAEELLNEIQNLKEWPEAVRSMQEKWIGKSIGANFHFKIKDNEETTIEVFSTKPETIFGASFIGIAFNHPIIERLVSKTPEILAFITKCSHITGSSELEKAEKEGVFTGLFVIHPFDSNIVLPVIITNFVLMDYGTGAIFGCPANDERDHELAVKMNLSIKQVIKADMDVQKTAYTEDGILVNSDFLNGLTSNEAKQEVIGEFEKLGIGKRSVNYRLKDWGISRQRFWGCPIPIIHCETCGIVPVPYKDLPVTLPDDVNFDGHGNPLDHHPSWKHVDCPKCDKPAVRETDTFDTFFESSWYFTRYCNSNAIEMTDKKACDYWLPVDKYIGGIEHAVMHLLYARFFTKVMNEQKYVSVREPFKGLFTQGMVLHATYKDEHNNWLYPEEVVKKGNEFFHKESNNRVVQGRIEKMSKSKKNLIDLETMQEQYGADAIRLFVLSDSPPEKDLEWSASGIEGCSRFINKLEYMFKAIDSLKDDVNSEINKELNRLVHFTIKLVAEDIKHFALNRAIARMRELSNAISAEISKDKIDVKTVRHGFNVLVQLLNPFIPHITEEIWQKLGNKKRLYNSSFPAFDESMLELDTYIMAVQVNGKLRDTYEFKTSVSEDEIKQVTVSLPKVQKFLEGKEPKKIILVPRKIVNILV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_META3
Sequence: MIERTFIKENVMETLVDEYLKNKLPRAGYSHMDVKKTPIGTRITVFAEKPGFVIGRKGKMVKELTETIATKYGVNKPQIEVKQIESPDLDAGVVAQKIASSLERGMHFRRVAHSAIRRVMAQGAKGVVVIVSGKLTGERSRTEKYMEGYMKHCGEPSEELVDQCHKIAKLKLGVVGVTVKIMPPEITLPDEIVIKDVPSKTTVETVEE
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL28_LACLM
Sequence: MSKECYFTGRKTVSSNNRSHAMNQTKRVVKPNLQKVTILENGELKTVWASAKALKKLPAGVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CALGL_OXYSC
Sequence: MAATLTPEQITEYKGIFEMFDEEGNGLVKTDDLESLMSLIGINPTKRDLANMAKDVDKDKKGTFNCDGFLVLMGIYHEKSKNQDEELRAAFKVFDKEHKGYIEWDTLKYVLMNAGEPLNEHEAELMMKEADKDGDGTIDYEEFVAMMTGESFKLTQ
What is the function of this protein?
May be involved in the cellular control mechanism of the secretion of toxins from the gland into the venom.
What are the official names of this protein?
Calglandulin.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family. Calglandulin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Not found in venom.
Protein: RR8_WELMI
Sequence: MDTIANLITSIRNAYIVDKKIVRVTATRTNENIGRILLQEGFIKSIREHKDGQKSFLIFTLKYRKKKEKRITLKRISKPGRKIYSDFPNMPKVLGGMGIAIVSTSRGIMTDREARQKKIGGEILCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS18_STRR6
Sequence: MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HISZ_STRGC
Sequence: MNKITLPIGMHDKLFKRARVTYEIERDISDFLMAQGFNRIDTPTLEHFEVFSDHVEPHHYHLFDKKGELLVLRPDVTSQIGRVIASTRVHTPTKFSYSGKVFHYQEELRGLANELSQAGIEIIGYPAREAVLEAIKTAKQSLDLAQVKSYQFEFSHAAILQTILESLVLDSQEEAQLLDYIRKKNRTGIFEFTQSRPSEFDDFLQELPYLFGPSQQVLARAREIVDNERILTALDDVEQVLRSLSDLLDQTTMDLGQVATMPYYTGLTFKVFGDRVPDAFLSGGRYDQLFKRFGATELTAIGWSLDIDSVYQAIHDDLPDEGGKEGDGR
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDH_MYCTU
Sequence: MPKSRRAVSLSVLIGAVIAALAGALIAVTVPARPNRPEADREALWKIVHDRCEFGYRRTGAYAPCTFVDEQSGTALYKADFDPYQFLLIPLARITGIEDPALRESAGRNYLYDAWAARFLVTARLNNSLPESDVVLTINPKNARTQDQLHIHISCSSPTTSAALRNVDTSEYVGWKQLPIDLGGRRFQGLAVDTKAFESRNLFRDIYLKVTADGKKMENASIAVANVAQDQFLLLLAEGTEDQPVAAETLQDHDCSITKS
What are the official names of this protein?
Probable CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RR3_DAUCA
Sequence: MGQKINPLGFRLGTTQSHHSLWFTQPKNYSEGLQEDQKIRDFIKNYVQKNLKISSGVEGIARIEIHKRIDLIQVIIYMGFPKLLIENRPGGIEKLQMNLQKEFNCVNRKLNITITRIAKPYGSPNILAEFIAGQLKNRVSFRKAMKKAIELTEQADTKGIQVQISGRIDGKEIARVEWIREGRVPLQTIRAKIDYCSYTVRTIYGVLGIKIWIFLDGE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SLTA_PROMU
Sequence: MGRFIFVSFGLLVVFLSLSGTGADCPSDWSSFRRYCYKPFKQLKTWEDAERFCWEQVKGAHLVSIESSGEGDFVAQLLSENIKTTKYHVWIGLSIQNKRQQCRSIWSDGSSVSYENLVKPFSKKCFVLKKESEFHKWFNIYCGERNLFMCKFLQPR
What is the function of this protein?
Snaclec that induces platelet aggregation in either human platelet rich plasma (PRP) or washed platelet suspensions.  It causes aggregation in a dose-dependent manner even in the absence of various platelet agonists such as ADP or von Willebrand factor (vWF).  Interestingly, it does not induce aggregation in rabbit PRP.  A monoclonal antibody against the platelet GPIb receptor blocks the aggregation induced by trimecetin, suggesting that it acts by binding to GPIb (GP1BA/GP1BB).
What are the official names of this protein?
Snaclec trimecetin subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS3_MYCUA
Sequence: MTLDPNVAARLKRNADGLFTAVVQERGSGDVLMVAWMDDDALDRTLKTREATYYSRSRGEQWVKGATSGHTQYVHSVRLDCDGDTVLLTVDQVGGACHTGDHTCFDATVLL
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCTP_BACSU
Sequence: MWEQLYDPFGNEYVSALVALTPILFFLLALTVLKMKGILAAFLTLAVSFFVSVWAFHMPVEKAISSVLLGIGSGLWPIGYIVLMAVWLYKIAVKTGKFTIIRSSIAGISPDQRLQLLLIGFCFNAFLEGAAGFGVPIAISAALLVELGFKPLKAAALCLIANAASGAFGAIGIPVITGAQIGDLSALELSRTLMWTLPMISFLIPFLLVFLLDRMKGIKQTWPALLVVSGGYTAVQTLTMAVLGPELANILAALFSMGGLALFLRKWQPKEIYREEGAGDAGEKKAYRAADIAKAWSPFYILTAAITIWSLPAFKALFQEGGLLYQSTLLFKMPFLHQQIMKMPPIAPSAMPLDAVFKVDLLSATGTAILAAVIVTGLFSKKFSSRDAFASLKETGKELWVPIMTICFVMGFANLANFAGLSSSIGLALAKTGDLFPFVSPVLGWIGVFITGSVVSNNALFGHLQVVTGAQIGAGSDLLLAANTAGGVMAKLVSPQSIAIAAAAVGQTGKESKLFKRTVAYSLILLLIICIWTFILARLGV
What is the function of this protein?
May play a role in L-lactate transport.
What are the official names of this protein?
L-lactate permease.
What is the protein family that this protein belongs to?
Belongs to the lactate permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SELA_ECO45
Sequence: MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRDSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVTKAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHSEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNKL_MOUSE
Sequence: MPSVSKAAAAALSGSPPQTEKPTHYRYLKEFRTEQCSLFLQHKCSQHRPFTCFHWHFLNQRRRRPLRRRDGTFNYSPDIYCSKYDEATGLCPDGDECPYLHRTTGDTERKYHLRYYKTGTCIHETDARGHCVKNGLHCAFAHGPLDLRPPVCDIRELQAQEALQNGQLSGGDGVPDLQPGVLASQAMIEKILGEDPRWQDSNFVLGSYKTEQCPKPPRLCRQGYACPHYHNSRDRRRNPRRFQYRSTPCPSVKHGDEWGEPSRCDGGDSCQYCHSRTEQQFHPEIYKSTKCNDMRQTGYCPRGPFCAFAHTEKSLAMVNEWSCRDLSSNSTSAYSSQPGSAKRKDSPSEGSQKATEDSKQNHLAVFSVAHPLAHSISSSVASSLASSTGSGSSSPTTLPTLPARALPLDPAGNTVGAVIGSALDLRLSDINIASLDKDLEEQDLGLTGPRSLAGSAPVTIPGSLPRSPSLHSSSSLSTSPLSSLSQSLSGPLVSSAMTPPQQPPPLRSEPATLGSAASSYSSLGLNGVPGSIWDFVSGSFSPSPSPILNSGPSASSSASPNSAELARVRRQLDEAKRKIRQWEESWQQVKQACDAWQREAQEAKERARVADSDRQLALQRKEEVEAKVKQLQEELEGLGLSSLPGLQSLGDISDIPLPKLHSLQSKLRLDLEAVDGVIFQLRAKQCVACQERAHGTVLRPCQHRVLCEPCAASTPECPYCKGQPLPW
What is the function of this protein?
May participate in a protein complex showing an E3 ligase activity regulated by Rac1.  Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2.  Intrinsic E3 ligase activity has not been proven.
What are the official names of this protein?
Putative E3 ubiquitin-protein ligase UNKL, RING finger protein unkempt-like.
What is the protein family that this protein belongs to?
Belongs to the unkempt family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Primarily localized in the cytoplasm but has the ability to shuttle between the nucleus and the cytoplasm.
Protein: HTR1B_DANRE
Sequence: MRLLILCASIILVPLLCDARIIKRYVIGCPERCDKSLCPPIPPDCLAGDILDQCDCCPVCAAGEGESCGGTGKLGDPECGEGLECAVSDGVGATTTVRRRGKTGVCVCKSSEPVCGSDGVSYRNICELKRVSNRAQKLQQPPIIFIQRGACGKGHEENPDSLRHRYNFIADVVEKIAPAVVHIELFRKNVFNREVAVASGSGFVVSEDGLIVTNAHVVANKHRVKVELKTGTTYDAKIKDVDEKADIALIKIDAPMKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESHDRQAKGKTATKKKYIGVRMMTLTPTLAKELKQRKNDFPDVTSGAYVIEVIPKTPAEVGGLKESDVIISINGQRITSASDVSTAIKTDESLRAVVRRGNEDIILTIIPEEIDP
What is the function of this protein?
Serine protease with a variety of targets, including extracellular matrix proteins and proteoglycans.  Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space.  Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins.  Inhibits signaling mediated by TGF-beta family members.  Consequently, may regulate many physiological processes.  Intracellularly, degrades TSC2, leading to the activation of TSC2 downstream targets (By similarity).
What are the official names of this protein?
Serine protease HTRA1B, High-temperature requirement A serine peptidase 1B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm, cytosol. Note=Also found associated with the plasma membrane.
Protein: RS1_RICPR
Sequence: MSIKLKQRFVPQLAAINCQFEEDFAQMLKTVDTSHIKEKTVVKGQVIEIKNDMIIVDVGLKNEGRIPKSEFLSLPEVGDVVEVFIEKIEGRNGRTILSREKAVKEELWGQLEIMCSKGEFVDGTIFGRVKGGFTVDLSGVVAFLPGSQVDVRPIKDPTSIMNIKQPFKILSMDKKLGNIVVSRRVILEESRSEARDEMLSKIKEGIVLEGVVKNITDYGAFIDLGSVDGLLHLTDISWGRVNHPSEVLEFNQKVKVMVIKFDEKTKRISLGIKQLDSNPWDAIKEEFPVGKKMTGKVTNFADYGVFLELKDGLEGLVHSSEISWLKSNQNPRKMLTIGQEVEFIVLEVDTEKHRVSLSIKQCQENPLIKFAENNPIGTIIKAPIRNITDFGIFVVLGNNMDGMIHEGDISWEDNGTDLLKSYKKGDEIECKVLAINFEKEQVSLGIKQLLPNPYQKISDEYKKSTIVKAVVTEIKDDGLVVLLNNKVTGFIKRVELSDEKDEQKPEMFKVHEEIDAKVVSIEKSTGRVLLSIKAHKIAERQKTLKEYGSSDNTTNMGDILANVLEEKK
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: TRPB_FRATN
Sequence: MSKLNAYFGEYGGQFVPQILVPALDQLEQEFIKAQADESFKQEFKELLQEYAGRPTALTKTRNIVKNTKTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLDLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVHSGSATLKDACNEALRDWSANYSKAHYLLGTAAGPHPFPTIVREFQRMIGEETKQQILAKEGRLPDAVIACVGGGSNAIGMFADFIDEKNVKLIGVEPAGKGIETGEHGAPLKHGKTGIFFGMKAPLMQNSDGQIEESYSISAGLDFPSVGPQHAHLLAIGRAEYASATDDEALDAFKLLCKKEGIIPALESSHALAHALKLAYEDPNKEQLLVVNLSGRGDKDIFTVHDILKEKGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RUVA_HELAH
Sequence: MTVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTASMLQTGQKARLKILQVIKEDAHLLYGFLEESEKILFERLLKINGVGGRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDETKPVHNEAFLALESLGFKSAEINPILKKLKPNLSVEEAIKEALQQLRS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RSGA_YERP3
Sequence: MSKNKLSKGQQRRVQANHQRRLRTDRKPELDDSQLGDAQEGIVISRFGQHADVEAVDGTQHRCNIRRTIKSLVTGDRVVWRPGLQAQEGVRVKGIVEAVHERTSVLTRPDLYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLEVEPLIVLNKIDLLDADGRKFVDGMMDIYRRIGYDVLEVSSQTREGMEAFENALTGRISIFAGQSGVGKSSLLNALLPPTDNEILVNTVSGNSGLGQHTTTAARLYHFQHGGDVIDSPGVREFGLWHLAPEQITQGFVEFRDYLGHCKFRDCSHTNDPGCALREAVEQGKIAEERFDNYHRILESMEQAKPRKTSDSDEK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2922_RHOE4
Sequence: MSGHSKWATTKHKKAVIDARRGKSFAKLIKNIEVAARTGGGDPTGNPTLYDAIQKAKKTSVPNDNIERARKRGAGEEAGGADWQTIMYEGYGPNGVAVLIECLTDNRNRAAGEVRTAMTRNGGNLADPGSVSYLFARKGVVTLEKNGQSEDDVLMAVLDAGAEEVTDLGETFEIVSEPQDLVAVRSALQEAGIDYDSAEADFRASVEVPLDVDGARKIFKLVDALEDSDDVQNVYTNIDLSDEVLAALED
What are the official names of this protein?
Probable transcriptional regulatory protein RER_29220.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBJ_EUGGR
Sequence: MSNSENTGRIPLWLVLTIIGLAAIALLALFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y1097_METNO
Sequence: MQTAPLRRPADLSHLSAHEARLACRRGEITGSTAGLAPGHVQANLAVLPKELATDFLLFAQRNPKPCPIIGVSAPGERRIPELGEDLDIATDIPGYRVWRNGEMVEERRDVADLWRDDLVAFAIGCSFSFEAAMVEDGLPLRHVEMGVRVPMYRTNIPCRPAGPFGGPMVVSMRPLKPADAIRAVQITSRFPAVHGAPVHLGLPEAIGIRDLAKPDYGDPVRIGADEIPVFWACGVTPQSVIAASKPAFAITHAPGAMLITDRRNTEFAVI
What are the official names of this protein?
Putative hydro-lyase Mnod_1097.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: CHRD1_MACFA
Sequence: MALLCYNRACGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKPPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEEDKKEEDNDEIKIGTSCKNGGCSKTYRGLESLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTKGRHMWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSRVEANSTLLNVHIVFEGEKEFDQNVKLWGVIDVKRSYVTMTATKIEINMRKAEPMQWASLELPAAKKQEKQKDDTTD
What is the function of this protein?
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2.  Proposed to act as co-chaperone for HSP90.  May play a role in the regulation of NOD1 via a HSP90 chaperone complex.  In vitro, has intrinsic chaperone activity.  This function may be achieved by inhibiting association of ROCK2 with NPM1.  Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling (By similarity).  Involved in stress response.  Prevents tumorigenesis (By similarity).
What are the official names of this protein?
Cysteine and histidine-rich domain-containing protein 1, CHORD domain-containing protein 1, CHP-1, Morgana.
Protein: TIG_DEIDV
Sequence: MAELISREGNKVEFKVAVPAAEVNRAYEQVWAGLARDVRVPGFRPGKAPRKVIEGRVGKGYVEQEVRDRLLQVHYPQAARELKLSLVDATIDPQDLNNGKDFTFNVRGETYPEVTLGDWSDLKLEATSPEITDDVLNRTLSDLQERNATFESVDRAIEASDQVTIEEQGEDGGTYPVYLDVAEAHVRDALLGKNKGDTVEITVPAHQHGDHEHAEHTVTVKIMDVKTKQLQELNDEFASSLNFESLDRLRADLRNELQRRAQQEGDNARREEFVAHLTERMQADIPQALLERRREAMMQEIQDDLSRQGVKWSEYETFMKEQGKLDEFMADLSKNAETRVKRDLALEKLAEDLKVQVSDAEFNQTMTMLAQANGLSPEQLSKQLGPNGINSYYASIVRERALQQALAQLSGPQAETVAADQGEQQAEGQEESAEKSEE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.