PharMolix/UniProtQA huggingface dataset:
Protein: FENR_PELPB
Sequence: MTLNKLYFDGGEEIRDLTIVGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQLAALYPEKHIYDVAGFPEVPAAGLVESLWKQTERYNPEVILGETVTRYRKLDDGSFEVTVSSGKVFLSRALLIAAGLGAFSPRKLPQLNNIDDLEGRSVFYAVKNISDFVGQRVVIVGGGDSALDWTVGLLNAAAEVTLVHRMHEFQGHGKTAREVLEAKESGRVNVFLNTEVRSVDREGEVLTAVHLRSKSGKSRRIEADRLLLLIGFKSDLGPLAGWDLELADNALVVDSHMKTSVDGLYAAGDIAYYPGKLKIIQTGLSDAAMAVRNSLTYIKPGEKIRHMFSSLKGAKEKRNAPDNG
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: PALB_ASHGO
Sequence: MEALLAVEETGNDLWKELKELYWAQYVQNSVDKVQFERYVRKVKSADDYWLVRALLAFSDSRKACTFNSRFEWLTMQAHGRQYPPLASKDAGKLIWNARREFRYAEPQQAAYKQLARPRGDAVADIQQHPDLGNCSMVCALINVKRTCGTADMVADCGDVAQVNLFFNGARRLVTLHRAEVRQNMRREQLAVLSPDMHDKLIEQAYFEVAHGMNYESMGSNTAMDTYMLCGWFPLVVETSEVDFPFVQRYLARGAMLALGTHATRTIDSFCLRKNHDYAVLDVCGTVFRIRDPLVAGNVIELAWEDVRTAFHLLYINWDAHTQCQLYEKFHFRYNSAVHNRFMSWLNKPTYRVVNDTESELPVYALFERHLSNRKYDNSIVGVISGENLVSDTEEGNNIGMQWVELTVPPHSSRILFYHSNTNTNCTLHLFSNSPRLKVAKWSSAESSRLAVLDGCWQPISKNLTFTHWPAFKFEIKHPETDGVHVSLQFCWANEHSAALFIYHASDYRYEKPLLHRPGPLPFPQAFFELALDTNTPYVVLCQSMDVGADAAFQLAIQTEKQGSVISTVPTSRAYGGLRFHTSKLVSTAAKRIELPFKVSRSTDLHITLYSKSSPLVLKCAVFSDGSDEAITATPGFVPINDYPYVLPITFAKERSLVLLIELQDTVPDSTVTIEIGSNCAFNFCGHDVDLARV
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
Calpain-like protease palB/RIM13, Cysteine protease RIM13.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family. PalB/RIM13 subfamily.
Protein: MIAA_ECODH
Sequence: MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: Y46S_SYNY3
Sequence: MSCRRLSTSGVLSMSVQNLSKQDVAALTAEDVAQLAQRLENDDYTDAFEGLRDWHLLRAIAFQREDLAEPYLYLLDNETYDEA
What are the official names of this protein?
Uncharacterized protein ssl0461.
Protein: PANB_ENTFA
Sequence: MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGDSLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGRLIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEAAKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQDMLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_NEOYE
Sequence: MNLEIMQNSLVNFAFGGLLIAMLVYWISLAFPGIGGLNRLATLITLLVNIALTLTLSSRWFANGYFPLSNLYESLLFLAWGLTFVHLFIENKTKSRLIGATAIPVAMFVTAFASLALPLEMQKASPLVPALKSNWLMMHVSIMMLSYAILILGSLLSILFLIITKGKDINLKGSSIGTGSYKVKNTDAKSTLIFSSQVGIVQEQSNMLINSTRMNLLESIDNLSYRTIGLGFPLLTIGIIAGAVWANEAWGSYWSWDPKETWALITWLIFAAYLHSRITKSWQGKKPAILASLGFLVVWICYLGVNFLGKGLHSYGWLA
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: THIG_PHOPR
Sequence: MLTIADKTFSSRLFTGTGKYANSQVMATSIIASGSELVTMALKRVDIDNRDDDILAPLIKAGVNLLPNTSGAKNAKEAIFAAKLAREALGTNWLKLEIHPDPKYLMPDPIETLAAAAELVRQGFIVLPYCHADPVLCKRLEEVGCAAVMPLGAPIGSNKGLASRDFLEIIIDQARVPVIVDAGIGAPSHAAEAMEMGADAVLVNTAIAAAADPIAMGRAFKLAVESGRMAYEAGLAGTINHAIASSPLTAFLDQTA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG13_SCHPO
Sequence: MPRLNTQLPRMYSAPPGHSKAVSTELNKDLSSVGGRSAKLGQVIHHCFYKTGLIILESRLNVFGTSRPRESSKNNKWFNLEIVETELYAEQFKIWKNIELSPSRKIPPMVLHTYLDISDLSKNQTLSVSDGTHSHAINFNNMSTMKIVLERWIVNLDGEALSTPLELAVLYKKLVVLFRSLYTYTHLMPLWKLKSKIHKLRAHGTSLKVGCALSTDDVLSNDFLPISAPISSSLGSSIATFSFSPVGTPAGDFRISVQYRKNCHFEVHDSDALLSNQLLSADKHQLAASNNSQDFEDGKQYDQPPPSFATRLAKQSDPNSLLQSEIQHLASIESITAQAAPLVTIHPFKSPSLSASPGSNFDNMSISPKVAVNRYIHRGPSATSLNKFSMISDAASKSRAKLPPLTSGSLKLNTLDISNTPNLRRFSSSFGPRERKESFSSRNRLPLVNHPIRSIFKHNVSENPITDHSEHAVYDSEFASKDDLSGFIQLLDSHAHHLNASEGSKSSGSFPGKVQTLTSGISPVAHPHNSLGSSNEIFDIDTYNHSIDNSGSRFTEAVKHNLGNSSHSIMRHHTLGTLRSRPSFSEKSTFPAPLTSISQASTFQGDNRSPSTVIPHTQTEVPSANDTSKQLASLHDMRKSQSPICARSATSAGLPRFEYHTSLSKSLEHSSTPASLQATKTPSPSFVLEPGIPQEYKKHFDNLSEERRQCLTPSTPTYEYYNEHNPNYDDDLLFTMTDMTLEPHDVSAIRLGSPKSDD
What is the function of this protein?
Activates the atg1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy.  Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation.  Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy.  Autophagy functions to supply nitrogen and is activated when cells cannot access exogenous nitrogen, thus ensuring that they can adapt and subsequently propagate.  Finally, atg13 is also required for glycogen storage during stationary phase and has a role in meiosis and sporulation.
What are the official names of this protein?
Autophagy protein 13, Meiotically up-regulated gene 78 protein.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Fungi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: AGM1_PIG
Sequence: MDLDAITKHSASHAKPDGLILQYGTAGFRTKADRLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEDDNGVKLVDPLGEMLAPSWEEHATHLANAEEQDLARALVAISEEAAVNLHQDAFVVIGRDTRPSSEKLSESVIDGVTVLGGQFHDYGLLTTPQLHYMVCCRNTGGQYGEATIDGYYHKLSTAFVELSKQASCSGDDHRTLKVDCANGIGALKLKEMKHYLPQGLSVQLFNDGTKGKLNHFCGADFVKSHQKPPEGIEMKANERCCSFDGDADRIIYYYCDVDGHFHLIDGDKIATLISSFLKELLLEIGESLTVGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKAQEFDLGVYFEANGHGTVLFSKAAEAKIRQLAKELEDKKGKAAKMLENVIDLFNQATGDAISDMLVIEAILALKGLTIQQWDALYTDLPNRQLKVKVADRQVISTTDAERQVVKPPGLQEAINDLVKKYKLSRAFVRPSGTEDVVRVYAEADSQENADSLAYEVSLAVFQQAGGVGERPQPGF
What is the function of this protein?
Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.
What are the official names of this protein?
Phosphoacetylglucosamine mutase, PAGM, PGlcNAc mutase, Acetylglucosamine phosphomutase, N-acetylglucosamine-phosphate mutase, Phosphoglucomutase-3, PGM 3.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ILVD_CORGL
Sequence: MIPLRSKVTTVGRNAAGARALWRATGTKENEFGKPIVAIVNSYTQFVPGHVHLKNVGDIVADAVRKAGGVPKEFNTIAVDDGIAMGHGGMLYSLPSREIIADSVEYMVNAHTADAMVCISNCDKITPGMLNAAMRLNIPVVFVSGGPMEAGKAVVVDGVAHAPTDLITAISASASDAVDDAGLAAVEASACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHAARRALFEKAGETVVELCRRYYGEEDESVLPRGIATKKAFENAMALDMAMGGSTNTILHILAAAQEGEVDFDLADIDELSKNVPCLSKVAPNSDYHMEDVHRAGGIPALLGELNRGGLLNKDVHSVHSNDLEGWLDDWDIRSGKTTEVATELFHAAPGGIRTTEAFSTENRWDELDTDAAKGCIRDVEHAYTADGGLVVLRGNISPDGAVIKSAGIEEELWNFTGPARVVESQEEAVSVILTKTIQAGEVLVVRYEGPSGGPGMQEMLHPTAFLKGSGLGKKCALITDGRFSGGSSGLSIGHVSPEAAHGGVIGLIENGDIVSIDVHNRKLEVQVSDEELQRRRDAMNASEKPWQPVNRNRVVTKALRAYAKMATSADKGAVRQVD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SYGB_YERPY
Sequence: MTQQTFLVEIGTEELPPKALRSLAESFAANFTAELDNANLSHGEVSWYAAPRRLAVKVANLSAAQADREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLVTDKGEWLLYRAHVKGQPAQLLLAGMVNTALSKLPIPKLMRWGDKETQFVRPVHTVTLLLGTEVIPGTVLGINSDRVIRGHRFMGEAEFTIDSADQYPQILLERGKVIADYELRKSIIKRDAEQAAQQIGGVADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYDTAGHLMPHFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFKTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWVAAQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLSLDLQTLTEEAVRLYGSKLTNAKVVDDVIEFMLGRFRAWYQDEGHSVDTIQAVLARRPTKPADFDARVKAVTYFRTLDAAAALAAANKRVSNILAKSTDTLNDHVHASILKEPAELKLATHLVVLRDQLEPVFAAGQYKEALVELAALRETVDEFFESVMVMAEDDAVRVNRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDRD_STAAE
Sequence: MLNRENKTAITRKGMVSNRLNKFSIRKYTVGTASILVGTTLIFGLGNQEAKAAESTNKELNEATTSASDNQSSDKVDMQQLNQEDNTKNDNQKEMVSSQGNETTSNGNKLIEKESVQSTTGNKVEVSTAKSDEQASPKSTNEDLNTKQTISNQEALQPDLQENKSVVNVQPTNEENKKVDAKTESTTLNVKSDAIKSNDETLVDNNSNSNNENNADIILPKSTAPKRLNTRMRIAAVQPSSTEAKNVNDLITSNTTLTVVDADKNNKIVPAQDYLSLKSQITVDDKVKSGDYFTIKYSDTVQVYGLNPEDIKNIGDIKDPNNGETIATAKHDTANNLITYTFTDYVDRFNSVQMGINYSIYMDADTIPVSKNDVEFNVTIGNTTTKTTANIQYPDYVVNEKNSIGSAFTETVSHVGNKENPGYYKQTIYVNPSENSLTNAKLKVQAYHSSYPNNIGQINKDVTDIKIYQVPKGYTLNKGYDVNTKELTDVTNQYLQKITYGDNNSAVIDFGNADSAYVVMVNTKFQYTNSESPTLVQMATLSSTGNKSVSTGNALGFTNNQSGGAGQEVYKIGNYVWEDTNKNGVQELGEKGVGNVTVTVFDNNTNTKVGEAVTKEDGSYLIPNLPNGDYRVEFSNLPKGYEVTPSKQGNNEELDSNGLSSVITVNGKDNLSADLGIYKPKYNLGDYVWEDTNKNGIQDQDEKGISGVTVTLKDENGNVLKTVTTDADGKYKFTDLDNGNYKVEFTTPEGYTPTTVTSGSDIEKDSNGLTTTGVINGADNMTLDSGFYKTPKYNLGNYVWEDTNKDGKQDSTEKGISGVTVTLKNENGEVLQTTKTDKDGKYQFTGLENGTYKVEFETPSGYTPTQVGSGTDEGIDSNGTSTTGVIKDKDNDTIDSGFYKPTYNLGDYVWEDTNKNGVQDKDEKGISGVTVTLKDENDKVLKTVTTDENGKYQFTDLNNGTYKVEFETPSGYTPTSVTSGNDTEKDSNGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQDSTEKGIKDVKVTLLNEKGEVIGTTKTDENGKYCFDNLDSGKYKVIFEKPAGLTQTGTNTTEDDKDADGGEVDVTITDHDDFTLDNGYYEEETSDSDSDSDSDSDSDRDSDSDSDSDSDSDSDSDSDSDSDSDSDSDRDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDAGKHTPVKPMSTTKDHHNKAKALPETGNENSGSNNATLFGGLFAALGSLLLFGRRKKQNK
What is the function of this protein?
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis (PubMed:9884231).  Mediates interactions with components of the extracellular matrix such as host DSG1 to promote bacterial adhesion to host cells.  Contributes to the resistance to killing by innate immune components such as neutrophils present in blood and thus attenuates bacterial clearance (By similarity).
What are the official names of this protein?
Serine-aspartate repeat-containing protein D.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A.
Protein: CLPB_GEOSL
Sequence: MIRPEKMTIKTQEALAGAQQLAARQGNGSIEPEHLLVSLLEQEGGLIAPIIQKVGGAPAALRSAADVLVKRLPQVSGATAQAYLSPALNRILDAAQREADTMKDEFVSTEHLLLGFFADRQCAAARALLDAGVSRDNVLAALMEIRGGERVTDQNPEDTYQALAKYARDLTDLARQGKLDPVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPETLKDKRLVALDMGALIAGAKYRGEFEERLKAVIREVAKSEGKVILFIDELHTLVGAGAAEGAMDASNMLKPALARGELHCIGATTLNEYRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYENYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAASRLRIEIDSMPTEIDEVERRIIQLEIEKQALLRESQDPHSLERLKKLADELEELKAKSAELKGHWQREKDIIGRVSSLRQRLEEKREEAKKAEREGNLARTAEIRYGEIPAIEKEIADRSAELEDIRKEGKMLPEEVDGELVAEIVSRWTGIPVSRMMEGEADKLVHMEDRLITRVVGQDEALVLVANAIRRARSGLSDPNRPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDMSEYQEKHTVARLIGAPPGYVGYEEGGQLTEAVRRRPYSIVLFDEIEKAHPEVFNVLLQVLDDGRLTDGQGRTVDFRNTVIIMTSNLGSQWIQQYGSSDYARMKAMVTETLKEGFKPEFLNRIDEIVIYHALPLEQIKKIVDIQVECLKQRLADRRIVLELSDKAREYLSREGYDPAYGARPLKRTIQRKIQDPLALALLEGKFQEGDTVRVDLSVSGEELVITKK
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_SULIN
Sequence: MSFPKELEKVLEITKAQNVWRRTQTLNLIASENVMSPLAESVYMSDFMSRYAEGKPYKRYYQGTKYTDEIETLAMDLMNEITNSKDCDLRPTSGTIANAAVFRVLAEPGDKALIAPVQAGAHVSHTKFGTLGALGIQHIEMPFDEENINVDVDKAIKMIEEVKPKFVVLGGSLYLFPHPTKELAPHVHAVGAKLVYDAAHVYGLIEGKVWSSPLKEGADIMTVSTHKTFPGPQGGAIFSDGSEVFKQVSRTIFPWFVSNHHLHRLPATAVTAIEMKYFGESYANQITRNSKALAEALAERGFKVIGENLGYTKSHQVAVDVRQFGGGNKIAKLLEDANIIVNKNLLPYDKPENVSDPSGLRIGVQEMTRYGMKESEMEEIAELFKKVIIDKKDVNEVKKEVIDMRKNFLEVKYTFDDMKDLEKYSSKSLKLII
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier.  Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TORD_SHEMA
Sequence: MSQVDINHARALVYQLLSSLFAREVDEQRLKELTSEAAQQFWEQLSLEANFTQSVDKIRSTLNGIKDDEALLELAADYCGLFLVGTKHSASPYASLYLSGEDEPLLFGEQHQQMSEFLHQSKLQVQSHFPEPADHLAVMLAYMAHLFCHSENSVQLSFLQTCFNSWLAKFINHLTQCNKNGFYSAVATLTLAWVKQDIAQLEPAVAIIS
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_METM6
Sequence: MVDYFDYNSLLTRAREQLPEEVFKDVRFEIPSADSFVEGNRTIIKNFKDIAKFMERDPQEFAKYVMKELGTAGDMEGVRLILQGKFGWRMVNEKIQNYVNEYVLCPECGKPDTKIVKEGRIHFLKCTACGAMKPVKTL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: RPOB_IDILO
Sequence: MAYSYSEKKRIRKDFGKRPQVLEVPYLLSMQLDSFKKFIEVDPEANNGLEAAFRSVFPIASYSGTAELQYVSYHMGEPAFDVEECQIRGITYSAPLRVKLRLVLFDKEAAAGTVKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDKGKSHSSGKVLYNARVIPYRGSWLDFEFDPKDNVFVRIDRRRKLPASIILRALEYSTEEILDMFFDTTYFEILKTKVKMQLVPERLRGETAKFDIKGAEGEVLVEKGRRITARHIRQLEQLDIKEMEVPAEYMVGKVLAKDYANKKTGEVVGHANDVLTLELIAELSEAGIKKIETLFVNDLDHGPYMSETLRVDSSNNRLEALVEIYRMMRPGEPPTREAAETLFDNLFFSEERYDLSTVGRMKFNRRLGREDLSGDNTLSREDIVEVMKKLIEIRNGLDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDNTMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLSTFSRTNEYGFLETPYRRIENGSVTDDVDYLSAIEEGNYVIAQANVGLNDKGELTEDLVPCRHKNEFTLMSKEQVQYMDVAPQQIVSIAASMIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGIERTIAVDSGVTVVAKRGGVVDYVDASRIVVKVNEEEMVPGEAGIDIYNLTKYTRSNQNTCINQKPTVNPGEPVTRGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILISERVAQEDRMTTIHIQELNCVARDTKLGAEEITSDIPNVGESALGKLDESGVVYVGAEVNGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVNGTVIDVQVFTRDGVEKDKRAVAIEEMQLAKVKKDLTEEFKILEEGIYNRARNLLLSNGFDEAKLASVDRSSWLTQDLGNEDAQAQLEQIAEQYQQIRDDFDTKFETKRRKITQGDDLAPGVLKIVKVYLAVRRSIQPGDKLAGRHGNKGVISTIIPVEDMPHDDEGNPVDIVLNPLGVPSRMNIGQILETHLGMAARGIGSKIEKMLKQQRAISELRDFLQQVYDLGESRQKVDITEFTDDEVMRLAGNLKAGLPTATPVFDGAVEEEIKALLKLADLPESGQIRLFDGRTGDKFERDVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDNNLQMEAGMPESFNVLLKEIRSLGINIELEQN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: DNAA_LEGPL
Sequence: MSTTAWQKCLGLLQDEFSAQQFNTWLRPLQAYMDEQRLILLAPNRFVVDWVRKHFFSRIEELIKQFSGDDIKAISIEVGSKPVEAVDTPAETIVTSSSTAPLKSAPKKAVDYKSSHLNKKFVFDSFVEGNSNQLARAASMQVAERPGDAYNPLFIYGGVGLGKTHLMHAIGNSILKNNPEAKVLYLHSERFVADMVKALQTNSINEFKRFYRSLNALLIDDIQFFAGKDRSQEEFFHTFNALLEGQQQIILTSDRYPKEIEGMEERLKSRFGWGLTVAVEPPELETRVAILISKAEQSNIELPYEVAFFIAKRIRSNVRELEGALRRVIANAHFTGKPITIEFVHEALRDLLALQDKLVTIENIQKTVAEYYKVKVADLLSKRRSRSIARPRQMAMALSKELTNHSLPEIGDHFGGKDHTTVIHACRKVKELIQDDSDFAEDYKNLMRILSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA_MYCA1
Sequence: MSFPYFISPEQAMRERSELARKGIARGKSVVALVYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADEPHFVVMGGTTEPITTALKDSYAENANLREATRIAVRALRAGSESSNGDQSALDVGSLEVAILDVNRPRRAFRRINRPTLENLLRELDSNGSDGNGDAPELNGGSSD
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AFR2_CRYNH
Sequence: MAFAGVGQGLGTYDRTEQTSGASLGRVASRAHFTDTHPSDDLPAQTEEHRAREVGHLARQLTRQSVGGTDDSSALFSYQQGSDLDPFSDKFCARRWTKLMFEALQTSGPARKAGLSFRNLDVHGFGSDADYQKTVGNLPLVGIGALRDLISNRKRKVQILNSMDGVLEAGEMLVVLGPPGSGCTTMLKTIAGEMNGIYLDESSSLNYRGITPKQIYGQFRGEAIYTAEVDVHFPNLTVGQTLSFAAEARAPRNPPGGISKKEYAKHMRDVVMSVFGISHTLNTIVGNDFIRGVSGGERKRVTIAEASLAGAPLQCWDNSTRGLDSANAIEFCKNLRLNADYIGISSAVAIYQAPQAAYDCFDKVSVLYEGEQIFFGKTTDAKQFFVDMGFHCPSQQTVPDFLTSLTSASERTPREGFEGKVPTTPQEFAARWKQSDKYQELLAQIAEFENKYPVHGKNYQEFLQSRRAQQSKRLRAKSPYTLSYGGQVELCLRRGFDRLRADPSLTLTQLFGNFIMALIIGSVFYNLPATTSSFYSRGALLFFAILMSAFGSALEILILYAQRGIVEKHSRYAFYHPSAEAVASALTDIPYKVINCIIFSLTLYFMTNLRREPGPYFFFMLISFTLTMVMSMLFRSIASLSRSLAQALAPAALLILGLVMYTGFAVNVANMRGWARWMNWLDPIAYGFESLMINEFHDREYECSAFIPMGPGYEGATGQQHVCSTAGAIAGSSVVNGDDYINLSYEYYHAHKWRNFGILIGFFLFFTAIYMTATEFITAKKSKGEILVFPRGKIPRALLAQSTHSHGSSDDVEGGKFAGGSKMKKQITGADRADAGIIQRQTAIFSWKDVVYDIKIKKEPRRILDHVDGWVKPGTLTALMGVSGAGKTTLLDVLATRVTMGVVTGEMLVDGRQRDVSFQRKTGYVQQQDLHLETSTVREALRFSAVLRQSNTISIKEKYEYVEEVLKLLEMESYADAVVGVPGTGLNVEQRKRLTIGVELVAKPALLLFLDEPTSGLDSQTSWNILLLLRKLTEHGQAILCTIHQPSAMLFEQFDRLLFLARGGKTVYFGEVGKGSHILIDYFEKNGAPKCPEGENPAEWMLAAIGAAPGSHSDVDWHQAWINSPERVEVRRELARIKETQGGKGEAALQNKDHEKSKSEVKAEYAEFASPLWKQFNVVLTRVWQQHWRTPSYIWSKAALCALSALFIGFSFFKSGTSQQGLQNQLFSVFMMFTIFGQLTQQIMPNFTTQRSLYEVRERPSKTYSWKIFILSNIVAEIPWAILMGAVIYFTWYYPIGYYRNAIPTGAVHLRGALMFLYIEMFLIFNATFAIMIVAGIATAETAGNIANLLFSMCLIFCGVLAPPSSLPGFWMFMYRVSPFTYLVDGMLSTAVAETSVVCSDIELLTLNPPSGESCGDYMSTYISNYGGYLVNENATTACEFCSMSSTNSFLAQFNIYYSNKWRDFGLLWAYVVFNIIAAVGIYWLARVPKNTGKEQASEPEGVQEKLVPAQSSEKKRESVSRGSESTAA
What is the function of this protein?
Pleiotropic ABC efflux transporter that confers resistance to structurally and functionally unrelated compounds including azoles such as fluconazole (FLC), itraconazole (ITC), posaconazole (POS), and voriconazole (VRC).
What are the official names of this protein?
ABC multidrug transporter AFR2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COQ7_PSEP1
Sequence: MATERHYSPLDRLLLQADTAMRTLLPFSGQPARPSPAIVQPDVDLDEQQARHIAGLMRINHTGEVCAQALYQGQALTAKLPEVRKAMEHAAEEEVDHLAWCEQRIRQLNSHPSVLNPLFYGMSFGIGALAGLVSDKVSLGFVAATEHQVCKHLDEHLEQLPHEDEKSRAILEQMRIDEEQHAESALEAGGYRFPAPVRFGMSLLAKVMTKSTYRI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ACDH_ECO55
Sequence: MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEANVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIASKSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA
What is the function of this protein?
Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A.  Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.