PharMolix/UniProtQA huggingface dataset:
Protein: GB_VZVD
Sequence: MSPCGYYSKWRNRDRPEYRRNLRFRRFFSSIHPNAAAGSGFNGPGVFITSVTGVWLCFLCIFSMFVTAVVSVSPSSFYESLQVEPTQSEDITRSAHLGDGDEIREAIHKSQDAETKPTFYVCPPPTGSTIVRLEPTRTCPDYHLGKNFTEGIAVVYKENIAAYKFKATVYYKDVIVSTAWAGSSYTQITNRYADRVPIPVSEITDTIDKFGKCSSKATYVRNNHKVEAFNEDKNPQDMPLIASKYNSVGSKAWHTTNDTYMVAGTPGTYRTGTSVNCIIEEVEARSIFPYDSFGLSTGDIIYMSPFFGLRDGAYREHSNYAMDRFHQFEGYRQRDLDTRALLEPAARNFLVTPHLTVGWNWKPKRTEVCSLVKWREVEDVVRDEYAHNFRFTMKTLSTTFISETNEFNLNQIHLSQCVKEEARAIINRIYTTRYNSSHVRTGDIQTYLARGGFVVVFQPLLSNSLARLYLQELVRENTNHSPQKHPTRNTRSRRSVPVELRANRTITTTSSVEFAMLQFTYDHIQEHVNEMLARISSSWCQLQNRERALWSGLFPINPSALASTILDQRVKARILGDVISVSNCPELGSDTRIILQNSMRVSGSTTRCYSRPLISIVSLNGSGTVEGQLGTDNELIMSRDLLEPCVANHKRYFLFGHHYVYYEDYRYVREIAVHDVGMISTYVDLNLTLLKDREFMPLQVYTRDELRDTGLLDYSEIQRRNQMHSLRFYDIDKVVQYDSGTAIMQGMAQFFQGLGTAGQAVGHVVLGATGALLSTVHGFTTFLSNPFGALAVGLLVLAGLVAAFFAYRYVLKLKTSPMKALYPLTTKGLKQLPEGMDPFAEKPNATDTPIEEIGDSQNTEPSVNSGFDPDKFREAQEMIKYMTLVSAAERQESKARKKNKTSALLTSRLTGLALRNRRGYSRVRTENVTGV
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: US8A_HHV1F
Sequence: MDPALRSYHQRLRLYTPVAMGINLAASSQPLDPEGPIAVTPRPPIRPSSGKAPHPEAPRRSPNWATAGEVDVGDELIAISDERGPPRHDRPPLATSTAPSPHPRPPGYTAVVSPMALQAVDAPSLFVAWLAARWLRGASGLGASCVGLRGM
What are the official names of this protein?
US8.5 protein.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: TX41E_ETHRU
Sequence: MTRHLIFAAMLLVCLFVCWNAVGARDARSAFSLEETAQDEHVMEERVFINPAGNREKNACLENCKSLPNCKNYEFCSK
What are the official names of this protein?
U-scoloptoxin(04)-Er1e, U-SLPTX(04)-Er1e, U-scoloptoxin-Er1.1b2d, U-SLPTX-Er1.1b2d.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-04 family.
What are the subcellular locations of this protein?
Secreted. Note=The mature toxins are clearly liberated from the multidomain precursors in the venom gland prior to venom expulsion and not by venom proteases upon secretion.
Protein: RL4_MYCPU
Sequence: MVEVKKTTKTKSTEEKAPKITKATKEKTSDKTALKAKTPKTKVSDKAESTPKKASVKTSAKAEKINVEKTEKVEKVNVEKVSIKRESSSKDVQKADFSNIKELNSKIFEFEKNYDQAIFDCILSERASRRQGTHKVKNRAEVSGTGKKPWKQKGTGKARAGSLRNPIFVGGGRAFGPSVNRNYKISINKKVRLNALMASLFALAKSNSVLLKTFSLEKPSTKDLVEELRKINASNLKRILLVSDDKNIFLSARNLKNVKVTKVTSLMIEDLVAADLLILSNENIKYLEGLIK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y284_BRUA2
Sequence: MTADVPNARLVDVELDESIGRSTPDVEHERAVAIFDLIEENSFHPVGDQKGGPYRLKLSLMESRLIFSITRENGDAVATHILSLTPLRRVVRDYFMICESYYQAIRSATPSKIEAIDMGRRGLHNEGSQTLQARLKGKIEVDFDTARRLFTLVCVLHWRG
What are the official names of this protein?
UPF0262 protein BAB1_0284.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: PFKA_ALIFM
Sequence: MVKKIGVLTSGGDAPGMNAAVRGVVRTALTEGLEVFGIHDGYLGLVEDRIEKLERHSVSDMINRGGTFLGSARFPEFKEVAVREKAIENLKKHDIDALIVIGGDGSYMGAKKLTEMGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDAIDRLRDTSSSHQRISIVEVMGRHCGDLTLMSAIAGGCEYVITPETGLNKEALIQNIQDGIAKGKKHAIIAITELMTDVNQLAKEIEAETGRETRATVLGHIQRGGQPGAFDRILASRMGNYGVKLLIDGHGGRCVGIQNEQLVHHDIIDAIENMRRPEKLELYKVAEELF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_LEPIN
Sequence: MAVPKRRKSKSKVRTKRAHHAIGKPNLVPCPNCNSYRLPHRICPTCGFYKTGIVLEPKVKKPKEEN
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: HIS8_SALSV
Sequence: MSTENTLSVADLARENVRNLVPYQSARRLGGNGDVWLNANEFPTAVEFQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELVIRAFCEPGKDAILYCPPTYGMYSVSAETIGVERRTVPALENWQLDLQGISDNLDGTKVVFVCSPNNPTGQLINPQDLRTLLELTRGKAIVVADEAYIEFCPQATLTGWLVEYPHLVILRTLSKAFALAGLRCGFTLANEEVINLLLKVIAPYPLSTPVADIAAQALSPQGINAMRDRVAQTVQERQYLVNALQQTACVEHVFDSETNYILARFTASSSVFKSLWDQGIILRDQNKQPSLSGCLRITVGTRQENQRVIDALRAEPV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: LBTA_DIESC
Sequence: MIGLSYLLVQVVSFAGILVIDHRWKLAAFRAPAAAALAVTASVALLLTWDVLGVRSGVFFRGQTDFMTGLLVAPEIPFEEVVFLAFLSHLALVCAAGVSRAVDHARDSRAARASRPSRMTGERR
What is the function of this protein?
Involved in the biosynthesis of C(50) beta-cyclic carotenoids (PubMed:17008032).  May have C(50) carotenoid beta-cyclase activity and produce the C(50) beta-cyclic carotenoid C. p. 450 from the C(50) carotenoid dihydrobisanhydrobacterioruberin (DH-BABR) (Probable).
What are the official names of this protein?
Putative C(50) carotenoid beta-cyclase subunit A.
What is the protein family that this protein belongs to?
Belongs to the lycopene beta-cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y5227_VIBVY
Sequence: MNTVFEIVSQARRKNKLKRELLDNEKKVRDNRKRVELLENLLDYIKPNMSQDEIMTIIKNMKADYEDRVDDHIIKSAEISKARRDISRRIRELTEEDKQASGKK
What are the official names of this protein?
UPF0265 protein VVA1227.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: O52M1_HUMAN
Sequence: MLTFHNVCSVPSSFWLTGIPGLESLHVWLSIPFGSMYLVAVVGNVTILAVVKIERSLHQPMYFFLCMLAAIDLVLSTSTIPKLLGIFWFGACDIGLDACLGQMFLIHCFATVESGIFLAMAFDRYVAICNPLRHSMVLTYTVVGRLGLVSLLRGVLYIGPLPLMIRLRLPLYKTHVISHSYCEHMAVVALTCGDSRVNNVYGLSIGFLVLILDSVAIAASYVMIFRAVMGLATPEARLKTLGTCASHLCAILIFYVPIAVSSLIHRFGQCVPPPVHTLLANFYLLIPPILNPIVYAVRTKQIRESLLQIPRIEMKIR
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 52M1, Olfactory receptor OR11-11.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MOAC_SALHS
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIVDGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEIQLQAEPEHNRVRIESLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVDAHD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: ZNUC2_HAHCH
Sequence: MLIGCASLTIQLGKRTILKDISMGVEPGEIVTIIGPNGSGKTTLLRAMIGAVAPRSGRLIRAPGLTLGYAPQTLHIDETLPMTVQRFMSLPKLGTASDIDAALSQAGVPGLEKQQIMSLSGGQLQRVLLARALLGRPRLLLLDEATQGLDPRGVADFYRQITSVRDELGCAIIMVSHELHLVMRKTDRVICLNGHICCEGEPDIVSRSPEYLALFGIDNDDEAAIALHSHGRGRSHHGSLSRAG
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PYRD_VIBCM
Sequence: MLYRLARAGFFQLDAEKAHDLAISNFKRFTGTPFDLFYRQQLPHRPVQCMGLTFKNPVGLAAGLDKNGECIEAFGAMGFGFVEVGTVTPRPQAGNDKPRLFRLVHAEGIINRMGFNNLGVDHLVENVKRAKYDGIIGINIGKNKDTPIEKGAEDYLICMDKVYPYAGYIAVNISSPNTPGLRSLQYGEALDELLAALKTRQAELAAKHDKYVPLALKIAPDLSDDEIQQICQSLLKNKIDSVIATNTTLDRSLVEGMKFANEAGGLSGRPLQNRSTEVIKCLYKELGEEIPIIGVGGIDSYISAKEKLLAGAKLVQVYSGFIYQGPGLVADIVKNL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HESX1_RABIT
Sequence: MSPNLQEGARLVEGKPSSTSFSIESILGLDQKKDDAPSMKPHRPWADTCSSLGKDANLRLHVPSFPNGISFPHPGDHPMPEERAMKYENYFSASERASLKRELNWYRGRRPRTAFTQNQVEVLENVFRVNCYPGIDIREDLARKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMA
What is the function of this protein?
Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland.  Possible transcriptional repressor.  Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'.
What are the official names of this protein?
Homeobox expressed in ES cells 1, Homeobox protein ANF.
What is the protein family that this protein belongs to?
Belongs to the ANF homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSLO_STRP7
Sequence: MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATGEVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNVLLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIYGDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYNFDEKDLEELIRDKS
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FGND_ASPFU
Sequence: MRRATLIPLAIWVAGAAAAAAASLPQFPSCDISLANIGLSQNSQIFFPNGSGWESETIRWTKYMAPTYAVSVRPAHVSDVTQVRFATRCKIPFLASSGQHGFDTELAELQNGMEIDLSAFRNVSVDAKKNTLTVGGGVRFMDVFDPVFNAGKEIRTSETDHQVGTGSGACVGMISPTLGGGVGRLSGTHGIISDQLLSVQMVTANGSLVTVSKKENSNLFWGLRGAGGNFGIVVEAVYQVTDLTSEKVVNLDYAFSTNDTGAIIDYLALFGPNMPPKLSFIIAALYNEKLFGGVGDPGCVDPNRGRQSANTIPPSLFQFAVIVSGLYAGPQSEAEQLLAPLLQNATLIKQNISVVPENKLVYAATFGSQGNSTIACSGKGVNRSIFGGAINTYDKATYVDFLKAFGDLVTTNTDLRGSVFFIEHFSNYQVQKIPDHTSAYPWRDITAHLLFNYAWNDPANQQLMLYSARKLPRLRALKKEWDPENVFRFHHPISMS
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of fumigermin that inhibits germination of spores of the inducing S. rapamycinicus, and thus helps the fungus to defend resources in the shared habitat against a bacterial competitor (PubMed:32083553).  The partially reducing polyketide synthase fngA alone is sufficient for the production of fumigermin (PubMed:32083553).  FgnA catalyzes the condensation of 3 malonyl-CoA units to an acetyl-CoA starter, and 3 methylations to yield fumigermin (PubMed:32083553).  It is remarkable that the five cluster genes including fgnA are conserved in distantly related fungi, supporting the assumption of a fumigermin cluster; it is thus possible that originally all five genes were functional, but that the genes encoding tailoring enzymes became inactive from mutations, similar to the case of the fgnA gene in strains A1163 and Af293 (Probable).
What are the official names of this protein?
FAD-linked oxidoreductase AFUA_1G00980, Fumigermin biosynthesis cluster protein AFUA_1G00980.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: COAE_BUCAP
Sequence: MIYIVALTGGICSGKTTVSDRFKKIGINVIDTDVIGRKIIEKNKKISDSIKKKFGKKILNKDNSINRFLLRNCIFNEKKSRLWLENILHPEILKKSKKKIKLIQSTWCLWVVPLLFEKKIQKKANRILLIDTPIRIQIRRMIKRDKININEAKKIISYQVRRKKRISLSDDIILNKNKNIEKLSLYIHYLNNFYIYLSKQNNPKNMKKII
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_PSEPK
Sequence: MPWLQVRLAISPEQAETYEDALLEVGAVSVTFMDAEDQPIFEPDLNTTPLWSHTHLLALFEANADPEQVFAHLRLLTGAELPEHQAEVIEDQDWERSWMDNFQPMRFGRRLWIVPSWHDAPEKDAVNLLLDPGLAFGTGTHPTTALCLEWLDGQQLEGTQVLDFGCGSGILAIAALLLGAREAVGTDIDVQAIEASRDNAQRNGIADEKLALYLPEHMPAMQADVLVANILAGPLVSLAPQLSGLVRPGGLLALSGILAEQGEDVAAAYAADFELDPIVVRDGWVRISGRRR
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3055_YERPE
Sequence: MQWLADYWWIILILLVGMILNGIKELRRLDHKRFLDNKPELPPHRDNNAQWDDEDDWPDQNKKK
What are the official names of this protein?
UPF0370 protein YPO3055/y1425/YP_2677.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RNY_BACVZ
Sequence: MTPMTVLISILLTLLGLVVGYYVRKTIAEAKIAGARGAAEQILEDAKRDAEALKKEALLEAKDEIHTLRIDAEQEVRERRNELQKQENRLLQKEENLDRKHEGIDKREAMLEKKDHSLNERQQHIEEMESKVDEMIRMQQSELERISSLTRDEAKQIILDRVENELSHDIAIMTKETENRAKEEADKKAKNILSLALQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRRETARIALDKLVQDGRIHPARIEEMVEKSRREVDDYIREMGEQTTFEVGVHGLHPDLIKILGRLKFRTSYGQNVLKHSMEVAFLAGLMASELGEDAKLAKRAGLLHDIGKAIDHEVEGSHVEIGVELATKYKEHPVVINSIASHHGDEEPTSIIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYEGVEKSFAIQAGREVRIMVKPDSINDLEAHRLARDIRKRIEDELDYPGHIKVTVIRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MDH_BARQU
Sequence: MARKKIALIGSGMIGGTLAHMIGLKELGDVVLFDIEEGMPQGKALDIAESSPVDGFDVSLTGANVYEAIEGADVVIVTAGVARKPGMSRDDLLGINLKVMEQVGAGIKKYASSAFVICITNPLDAMVWALQKFSGLPKQKVVGMAGVLDSARFRYFLSKEFKVSVKDVTAFVLGGHGDSMVPLVRYSTVGGISLPDLVKMGWTTQEKIDQIIQRVRNGGAEIVGLLKTGSAFYAPAASAISMAEAYLKDIKRVVPVATYLSGEYGVKDTYVGVPVVLGAGGVERVIEIDLDKKERSAFEQSVNAVKKLCEACIAIAPCLK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: KAD_DESVH
Sequence: MNILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKQAKAFIERGDLVPDDITIPMVLETLKSKGANGWLLDGFPRNMVQAQKLWDALQAEGMKLDYVIEILLPREVAKNRIMGRRLCKNDNNHPNNIFIDAIKPNGDVCRVCGGELSARSDDQDEGAIGKRHDIYYNTVDGTLAAAYFYKDLAAKGMTKYIELDGEGAIDAIKDKLLAQLS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM34_BOTFB
Sequence: MAFNFNWSPLTADAEFYQRAQEMLTAALNKSPKPPIIKDDILVNELNLGSVPPDLEILEIGDLAEDRFRGIFKMCYSGDAFLTLKTRVQANPLNNHLFSKPSFTSPQPLAADAGLTIPLQITLSDIKLSAFIIVVFSKSKGLTLVFRNDPLESLKVSSTFDSIPFIKDYLQKEIEQQLRTLMMDELPAIIHRLSLRLWCPEYRAKEDQEMAEAAKKTKDEVAVDPFASPPQDAVDARGNVLDATEISNLSLDGGSEIHSLFSQKNLLRLAALTNSHRTLSLFTPSIRDAVFRAWAPSERGDSAGTTTPATPSLQRPQSSLGSQSTTYTFSNRSSDDGHGGIPSRPSLVNMNSATTGLSLGANRGSRSHPTRKKKNRVVNLRKPKTTESSESGESETASTTAVSEPTVPSRIPEEPEDLPVTPPSGKVRFNSIDLGDSPKKLPPSRSMTPEQVKMDQIPSLTVQPSTPINTQEQKRPAYNQSASTSYTPEKSAITPPHTPFSYPHGLHFSTTESPSGILEQAWIMKMASELARRQHDDKTARQGFWSTSSNGDDAPPAYEPKAL
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: FABA_SHEFN
Sequence: MEKANSFTKEQLVACGHGNLLGPNRPRLPVDNMLMIDRIITINEDGGAFGKGEIIAELDITPDLWFFDCHFISDPVMPGCLGLDAMWQLVGFFLGWEGAEGKGRALGVGEVKFTGQVLPDAKKVTYKLNIKRKIHRKLVMGIADATMEVDGRQIYSATDLKVGIFSDTSTF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_SYNS9
Sequence: MTSSGKVRIYELSKDLGLENKDVLDAAEKLSIAAKSHSSSISDSEAGKIRSLLGKGASPSQPTAPAAKPAPAKPAAGKSILSVKKAPASPGVTAPVAAAKPQAPAQPAASKPLQPSVKAVAPPARPAPAGSTSAGSTPNKPATAPARPTAATTTSTPRPAAAAAPSRPAPSKPQGAPKPQVVGKPSAPELVSKPTPATKPTGAAKPAIVSKPITAAKPAVVAKPAAAKPTIVKPTAPTPRPASSPAAASSAPPPASTPRPAPSRPTPRPAAAPSRPGAPQGQKPQIVSRAGAPPRPGTPPRVGAPTKTGTPARPTPRPELVGKPVPRRTGGVGAPQRPGTGVPQRQGGPARPGAPTRTGKPGAPTRPGGNTLELVGKPIRRDGSSASGRPGAPTRPGAPTRPGMPGGMRKPVAPGELMQLQKPISRPAAPAPRRPDAPNRPTEAAGTATPPVARPTAPSAPRRPGFRPGAPGGQRRPGRPDWDDSAKLEALRSRSPQKQRQKVHIIGENDDALAAQTGGFAGEQQAMVLSASLARPAKPKAQQRTAPKPVAAVRKRRKETARQRQRRRAMELRAAREAKQVRPEMIVVPEDNLTVQELADMLSIESSEIIKSLFFKGVIATVTQTLDMPTIEAVAKEFDVPVLQDDVEEAAKKTVEMIEEADLKHLIRRPPVVTVMGHVDHGKTSLLDAIRQARVAAGEAGGITQHIGAYQVEIQHKDEARKLTFLDTPGHAAFTAMRARGTKVTDVAVLVVAADDGVRPQTLEAISHARAAEVPIVVAINKIDKEGASADRVKQELSEQNLLAEEWGGDVVMVPVSAIKGENIDKLLEMLLLVTEVEDLQANPDRPARGTVIEAHLDKAKGPVATLLIQNGTLKTGDVLAAGPVLGKVRAMVDDNRQRLKEAGPSFAVEALGFSEVPTAGDEFEVYPDEKAARAVVGDRASNARATRLAQQMASRRVSLTAMSGQANEGELKELNLILKADVQGSVEAILGSLEQLPKDEVQVRVLLSAPGEITETDVDLAAASGAVIIGFNTSMASGAKKAADATGVDVRDYDVIYKLLEDIQLAMEGLLEPELIEEALGEAEVRAVFTIGKSAVAGCYVNTGKLHRNCRVRVHRGKQVVYTGDLDSLRRNKDDVKEVATGFECGVGADRFANWEEGDRIEAFKMVTQRRKLTT
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK20_NICTO
Sequence: MTRIKRGYIARRRRTKIRLFASSFRGAHSRLTRTITQQKIRALVSAHRDRDRKKRDFRRLWITRINAVIRERGVSYSYSRLIHDLYKRQLLLNRKILAQIAISNRNCLYMISNEIIKEVDWKESTRII
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CP17A_RAT
Sequence: MWELVGLLLLILAYFFWVKSKTPGAKLPRSLPSLPLVGSLPFLPRRGHMHVNFFKLQEKYGPIYSLRLGTTTTVIIGHYQLAREVLIKKGKEFSGRPQMVTQSLLSDQGKGVAFADAGSSWHLHRKLVFSTFSLFKDGQKLEKLICQEAKSLCDMMLAHDKESIDLSTPIFMSVTNIICAICFNISYEKNDPKLTAIKTFTEGIVDATGDRNLVDIFPWLTIFPNKGLEVIKGYAKVRNEVLTGIFEKCREKFDSQSISSLTDILIQAKMNSDNNNSCEGRDPDVFSDRHILATVGDIFGAGIETTTTVLKWILAFLVHNPEVKKKIQKEIDQYVGFSRTPTFNDRSHLLMLEATIREVLRIRPVAPMLIPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEWDQPDQFMPERFLDPTGSHLITPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDVSDDKQLPRLEGDPKVVFLIDPFKVKITVRQAWMDAQAEVST
What is the function of this protein?
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis.  Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways.  A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage.  The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol.  Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione.  Has 16-alpha hydroxylase activity.  Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA.  Also 16-alpha hydroxylates androgens, relevant for estriol synthesis.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Microsome membrane.