PharMolix/UniProtQA huggingface dataset:
Protein: 11011_ASFM2
Sequence: MKVLLELLLGYSVLILAHELPYLPSTRHPPKEELPYWCTYVKNCDFCWDCQNDICKNKITNESISINSIVNCRVTRDSPSQSCFYEISVKMPNHHSMECSHPRPYTGNEIFMEKWGGGGDYWPIIIRHCCFYLVFSIAFVGYIVFVYNKNLHLNTTMKLLALLSILIWLSQPALNRPLSIFYMKQNLPRTYTPPVRELEYWCTYAKHCDFCWTCKDGMCKNKVFRDHPIITQNDYIVNCTVSRWHDRCMYEAHFRIHYQHNMNCSQPKDLEWFIELKRHVINQDDL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-3L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: SYFA_SACS2
Sequence: MISMLSENEAKILFFLKDLKKTNSVELAIKMGIPESSVLSLIELLREKGYVKTEVKSEKHYVLTEEGRKRKESGLPEDILINTLNGQEKDLNEIKNILNKDFNIAISWAKRKGLIDIKEGKVIPKVKTYMSSEYLALSNLERADSNTINLLKKRGLIEEKERKIVSVELIKEPKESEIGISNLNRELIISGEWKKYKLKKYNVEAFPPYYTISKKHYFREFLEKVKDIMISLGFKEINTGYIEMEFYNFDLLFQPQDHPAREIHDSFSVEGSGKIEDKDLLNNVKEIHEKFWKYEWKQDITLRLMLRSQTTATTARVLASRPKAPQKVFTLGKVFRPDAIDATHLIEFHQLDGVIIDNNFTFKELLGVLKEIFYRLGIKEVKFKPAYFPFTEPSVEAYGYLEKLGWVEMCGAGLLRPEILSSVGIDSTAGAWGIGIERLAMSFLNISDIRLLYSNNIEYIRDTKVKIE
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBL_METIM
Sequence: MKRVVAAGTFDILHPGHYEFLKFAKSLGDELIVIVARDKTVEKIKGRKPIIPEEQRRAMVEALKPVDKAILGSLNNKLEPIIELKPDIIVLGPDQRTFDEEELKRELKKYDLSPKIVRFNKYIKCPFHSSYDIVKEILKRYGGKE
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: CYB_LAMGL
Sequence: MTNIRKSHPLLKIVNNAFIDLPAPSNISSWWNFGSLLGICLIMQIMTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWIIRYLHANGASMFFICLYIHVGRGLYYGSYAFLETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTTLVEWIWGGFSVDKATLTRFFAFHFILPFVIAALAGVHLLFLHETGSNNPTGISSDMDKIPFHPYYTIKDILGALLLILTLLLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALIPLLHTSKQRSMMFRPISQCLFWTLVADLLTLTWIGGQPVEPPFIMIGQVASILYFSLILILMPVAGIIENHILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLO2_ECO55
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAITANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLNKLSALPDDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: CYFIP_DROME
Sequence: MTEKITLADALSNVEVLDELSLPDEQPCIEAQPCSIIYKANFDTNFEDRNGFVTGIAKYIEEATTHANLNVLLDEGQKHAVMLYTWRCCSRAIPQPKSNEQPNRVEIYEKTVEVLAPEVNKLLNFMYFQRKAIEAFSGEVKRLCHAEKRKDFVSEAYLLTLGKFINMFAVLDELKNMKSSVKNDYSTYRRAAQFLKVMSDSHTLQESQNLSMFLATQNKIRDTVKDTLEKIVGYEDLLSDVVNICVHMFETKMYLTPEEKHMLVKVMGFGLFLMDSDACNINKLDQKKKIRLDRIDRIFKNLEVVPLFGDMQIAPFNYIKRSKHFDSSKWPLSSSNAISPQADLMVHLPQIREDHVKYISELARYTNEVTTTVKENPSDAENRITADLALRGLQLLSEWTSVVTELYSWKLLHPTDHHQNKECPVEAEEYERATRYNYTSEEKFALIEVIAMIKGLQVLMARIETVLCEAIRRNIYSELQDFVQLSLREPLRKAVKNKKDLIRSIIMSVRETSADWQKGYEPTDDPVAKGKKDPDGGFRIQVPRLNVGPSSTQLYMVRTMLESLIADKSGGKRTLRKDIDGNCLLQIDTFHKTSFYWSYLLNFSDTLQKCCDLSQLWYREFYLEMTMGRKVNKCLVRHQHNEECKDLITMEKRIQFPIEMSMPWILTDHILQTKEPSMMEFVLYPLDLYNDSAYYALTVFRKQFLYDEVEAEVNLCFDQFVYKLSEQIFAHYKQLAGSIFLDKRFRLECEVLGFNFQSYPRNNRYETLLKQRHVQLLGRSIDLNKLITQRINANMHKSIELAISRFEGNDITGIVELEGLLEANRICHKLLSKYLALDNFDGMVKEANHNVLAPYGRITLHVFVELNYDFLVNYCYNAATNRFIRTKVNLSSSQAIQREKPPQMSHYYLWGSKQLNAAYSTQYGQYTGFVGSPHFHAMCRLLGYQGIAVVMDIILKDIVKPLIQGSLLQFTKTLMIAMPKSCKLPRCEYGSPGVLSYYQAHLTDIVQYPDAKTELFQSFREFGNSIIFCLLIEQALSQEEVCDLLHAALFQNIFPRPFCKENEKPEAKQKRLEAQFANLQIVSNVEKIGTAKQAMIAREGDLLTRERLCCGLSIFEVILNRVKSYLDDPVWCGPPPANGIIHVDECSEFHRLWSALQFVYCIPVRGTEYTIEELFGEGLNWAGCVMIVLLGQQRRFEALDFCYHILRVQRVDGKDEDVKGIQLKRMVDRIRRFQVLNSQIFSILNKYLKGGDGEGSNVEHVRCFPPPQHPSVISSSSHYQDPQKLRQSINN
What is the function of this protein?
Plays a role in guidance and morphology of central and peripheral axons and in synaptic morphology.  Also required for formation of cell membrane protrusions and for bristle development (PubMed:12818175, PubMed:14588242, PubMed:15269173, PubMed:15385157).  Plays a role in regulating mitochondrial activity, energy metabolism and membrane potential which maintains normal gamma-aminobutyric acid (GABA) signaling and ensures normal social behavior (PubMed:32200800).
What are the official names of this protein?
Cytoplasmic FMR1-interacting protein, Specifically Rac1-associated protein 1, DSra-1.
What is the protein family that this protein belongs to?
Belongs to the CYFIP family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Accumulates in central axons and motor neuron terminals.
Protein: GSA_HYDS0
Sequence: MTNKEAFELAKKYMPGGVSSPVRAFKSVGAEPIVVNRGFGAFVEDIEGKKYIDYMLSFGPLILGHRSEIVVSKIMEALDKGNSFGITNMYEIELSELIIKASKVIDKVRFVSSGTEAVMSAIRLARGITNKPYIIKFDGCYHGFSDSVLVGAGSGVATLGIPGTPGIPKEFAALTIVLDYNDENALEEAFIKYKNQIAAVLVEPVAGNMGVVLPKESWLKKLRDITKENDALLIFDEVITGFRLALGGAAEYFGIEPDIVCYGKIIGGGMPIGAYGAKNHIMERVAPEGPIYQAGTLSGNPISVASGLAILKTLIKDIAIYDRLSELRAYLTYTLSKMLSEKGIPHRINEIASMFTIFFTDKDVIDFKSAKTSDTALFGKFFRNALKEGVLMPPSQFEAWFLSTAHTKDVVDTTLEKLKKAIDLL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK1_DROME
Sequence: MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFNGFQSGLVRN
What is the function of this protein?
Plays a key role in the control of the eukaryotic cell cycle (PubMed:2120044, PubMed:15581871).  It is required in higher cells for entry into S-phase and mitosis (PubMed:2120044, PubMed:15581871, PubMed:29746464).  In embryos, promotes the release of Rif1 from chromatin during mid-blastula transition (PubMed:29746464).  p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (PubMed:2120044).
What are the official names of this protein?
Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOP_HAEIN
Sequence: MKISARNQLKGKVVSIENGSVNAIVHIDIGGGNVLSSTVSLAAVKELNLEVGKEAYAIIKATSVMVGVE
What is the function of this protein?
Binds one mole of molybdenum per mole of protein and contains a pterin.
What are the official names of this protein?
Probable molybdenum-pterin-binding protein.
What is the protein family that this protein belongs to?
To C.pasteurianum MOP proteins.
Protein: Y5363_DICDI
Sequence: MKGIIVSDGVYREEDVFAGQRIFMTPELIEKTMLGLVQKYNQYRPTTKSSPYAVAAWLLHAFVSIHPFIDGNGRMGRILANLVLFSYGFPFPVPISADNDEYIKSLRLADRYYEKGRDTSHLALIILNSSHSIYKNYLSNLEL
What are the official names of this protein?
Fido domain-containing protein DDB_G0283145.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACSA_CUPMC
Sequence: MSAIESVMQEHRVFNPPASFAKTAAIPSMEAYQALCDEAAKDYEGFWARHARELLHWHKPFTKVLDESNAPFYKWFEDGEINASYNCLDRNVEKGLGDKTAIVFEADDGTVTRVSYQELLAKVSRFANGMKALGIKKGDRVVIYMPMSVEGVVAMQACARIGATHSVVFGGFSAKSLQERLVDVGAVALITADEQMRGGKALPLKAIADEALTLGGCEAVKNVIVYRRTGGNVAWTEGRDRSMEDVAAGQSDNCPAEPVGAEHPLFVLYTSGSTGKPKGVQHSTGGYLLWALMTMRWTFDIKPDDMFWCTADIGWVTGHTYITYGPLAAGATQIVFEGVPTFPNAGRFWDMIQRHKVSIFYTAPTAIRSLIKAAEADEKIHPKQYDLSSLRLLGTVGEPINPEAWMWYYKNIGRERCPIVDTFWQTETGGHMITPLPGATPLVPGSCTLPLPGIMAAIVDETGQDVPNGNGGILVVKRPWPSMIRTIWGDPERFKKSYYPEELGGKLYLAGDGSIRDKETGYFTIMGRIDDVLNVSGHRMGTMEIESALVSNPIVAEAAVVGRPDDTTGEAICAFVVLKRSRPTAEEAVKIAAELRNWVGKEIGPIAKPKDIRFGDNLPKTRSGKIMRRLLRSLAKGEDITQDTSTLENPAILDQLKQAQ
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: FLIC_SALMC
Sequence: MAQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAAGADKYRVDINSGAVVTDAAAPDKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGDGGNGKVSTTINGEKVTLTVADIATGATNVNAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANATGDKITLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin, Phase 1-D flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: Y3816_MYCBO
Sequence: MARTDDDSWDLATGVGATATLVAAGRARAARAAQPLIDDPFAEPLVRAVGVEFLTRWATGELDAADVDDPDAAWGLQRMTTELVVRTRYFDQFFLDAAAAGVRQAVILASGLDARGYRLPWPADTTVFEVDQPRVLEFKAQTLAGLGAQPTADLRMVPADLRHDWPDALRRGGFDAAEPAAWIAEGLFGYLPPDAQNRLLDHVTDLSAPGSRLALEAFLGSADRDSARVEEMIRTATRGWREHGFHLDIWALNYAGPRHEVSGYLDNHGWRSVGTTTAQLLAAHDLPAAPALPAGLADRPNYWTCVLG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mb3816c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: PYRB_SULIK
Sequence: MRLRHVVSSLDLTRDDYFRIFELADKFSNVKKLNYLSGKVVSLAFFEPSTRTAQSFHTAAIKLGADVIGFASEESTSIAKGENLADTIRMLNNYSNCIVMRHKFDGAALFASEISDIPIINAGDGKHEHPTQALIDLYTIYKVFGEIDGRTFGLLGDLKYARTVNSLLRALTRFKPKKVFLISPSQLKVRREILDGLNYPVIETENPYDVIQDIDVLYVTRIQKERFVDEVEYEKVKESYVVDLKLVNMMKKDGIILHPLPRVTEIDRKVDKTTNAKYFYQASLAVPLRMALFYEVLGERKDD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CH10_MYCMM
Sequence: MAKVNIKPLEDKILVQANEAETTTASGLVIPDTAKEKPQEGTVVAVGPGRWDEDGEKRIPLDVAEGDTVIYSKYGGTEIKYGGEEYLILSARDVLAVVSK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_BORDL
Sequence: MFVNKKYTAKGKNLPSSPKKVRPIADNIRGKPYNEAVAILCSMPNKGAKLLGKVVKSAASNAMYHNRNLSEDMIFVKTVMVDDGRKRRSIWPRARGRADRLINRSCHIFVEVYEKMYGGE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: UBIA_FRATO
Sequence: MNKQQLKAYFMLMRLHRPIPILLILWPTLTALVLASHGLPDISYLVIFTIGVVVMRTVGCIINDIADVDFDKHVARTNTRPLTSGQLSIKNAIWLCISLTLVAFICVLFLNLYTILLSFVALFLAILYPFCKRFFAIPQLILGLAFNFGIFMAFSAIQNQIPVEAWIFYIATICWTIAYDTIYALADREFDLETGIKSSAVLFGNKVFRYILLFNFLSLLLLIILGIYCDFNSFFYLGVVICSLFFVRNYFLYKKLGITNCINAFSANHWIGLIIFIIAVIQYI
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LAMP3_MOUSE
Sequence: MPGQISAVAVLFLSLTVILHGYQIREKEFPKARGYLQYTATSAEQITTKPLLQLINQRSHITLASRFKDDYIQMAAETSAIENTAHITMKTVTPVTTKSLPPISSASYTFVRSNNAHMTASSTDDTIGSGSIAHLPVPTTRASLAIVNYITGRATQLGGQTTLPKTFFTASHKSTTNQRPTLSTNVLGTSTPTHKDRSTTSPVPLVPRPTLVTWSSPAKIGTYEVLNGSRLCIKAEMGLALIVQEKDLDSATQRYFNIDPSLTHASGKCDSQKSNLFLNFQGGSVNITFTKEENLYYISEVGAYLTISNTEKTYQGKKNTLMMFETVVGHSFKCVSEQSIQLSAQLQMKTMNIHLQAFDFEGDSFGNVNECLSDYTVVLPMVAIIVVVICVVGLSVYKIRQRHQSSAYQRI
What is the function of this protein?
Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction.  Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process.  Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway.  May also play a role in dendritic cell function and in adaptive immunity.
What are the official names of this protein?
Lysosome-associated membrane glycoprotein 3, LAMP-3, Lysosomal-associated membrane protein 3, DC-lysosome-associated membrane glycoprotein, DC LAMP.
What is the protein family that this protein belongs to?
Belongs to the LAMP family.
What are the subcellular locations of this protein?
Cell surface. Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Note=During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3. Detected on lysosomes in mature dendritic cells.
Protein: RL35_RICBR
Sequence: MPKLKTKSAVKKRFKLTASGKVVASQAGKKHFMRRRTKAQIRNLRGTTILCDQDGYNIKKYFLPYGTN
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: K1C18_ACIBE
Sequence: MSYRPGSYSVSSMRPVGSVRSSQVMTVQRSMPLASAASVYGGAGGRGSRISVGGSSSGFGSGLGSGAGGSYSSMSVSGSGLVGNEKETMIGLNDRLAAYLETVRNLEQANSKLEFQIREALEKKGPTTRDLSPFEKTLEDLRKKVYDMTMDNSRLVLQIDNSRLAADDFRVKFESEYSIRQSVESDIIGLRKVIDDTNMGRMNLESEIESLKEELIFIKQNHNQEVNDLRNQIAQSGVQVDVDAPKGQDLAQVLAEVRAQYESMAQKNRDELKAWHENKLTEVEVEVIQNTEALQGARTEVTELRRQMQSLEIELESQRSMKASLEDSLRDTEMRNNMEMERYNNMILQLEAELGQLRGNIQMQASEYEALLNIKMKLEAEIATYRRLLDGEDFRLQDALVDQSSTKSIKKVTVTQTLVDGKVVSESTNTKEIGK
What is the function of this protein?
When phosphorylated, plays a role in filament reorganization.
What are the official names of this protein?
Keratin, type I cytoskeletal 18, Cytokeratin-18, CK-18, Keratin type Is, Keratin-18, K18.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RK32_ACOCL
Sequence: MAVPKKRTSISKKRIRKNFWKKKGYFAAVKAFSLAKSVSTGQSKSFFVRQTSNKSLE
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: METK_METC4
Sequence: MPRSDYLFTSESVSEGHPDKVSDRISDTVVDAYLSAMPEARLGVETLTTTNRVVIAGEVRGPDSVTFKDLEELTREAVRDIGYEQSGFHWKNNDVAIHLHAQSADIAQGVDAAGNKDEGAGDQGIMFGYAADETPALMPAPIFYAHKILKDLADARKAKQGDAAKLGPDAKSQVTVRYANGRPVEVTQIVLSTQHLDESLDSADVRAIVEPYILKALPQGWVNEGTVWHVNPTGKFVIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNVVAAGLARRATIQLSYAIGVAKPLSIYVDLHGTGTVDEAKLETVLMDALDLSPRGIRTALQLNKPIYARTSAYGHFGREPDADGGFSWEKTDLADKLKSAF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_PEDPA
Sequence: MKAVHMNASGQVQAVGFRYTTKLLADRLKVTGWVKNNPDGTVEIEAQAPDAVLDQFIDGVKASPSPSGRVNKLTVKSIPLFEGQDFIVKY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: NTPPA_ECOUT
Sequence: MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKAQAGVAQTAQDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRKINGSFHAVVGLPLVETYELLSNFNALREKRDKHDG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2B_CHLRE
Sequence: MNVYVTLKTKLVAELRQIKQTLQTERNIIRVLRRKLKQIAAQKRFIKFLPKLRYLPTPVTKIEQTARFLVKKFVDPKMKYPMDSIYDKKLSRQSKKVAASRKKKWQRLEKYLGGISNMTKIKEKQIANNVAIIIGQQEEMNAVRECQKLGIKMFHIVDTNCNPGLADHFIPANDDARNSIKFILGKFLTRIRLAHKIKVKFKKTSLKK
What are the official names of this protein?
Putative 30S ribosomal S2-like protein.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATOH7_MOUSE
Sequence: MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIIALTRILAEAERDWVGLRCEQRGRDHPYLPFPGARLQVDPEPYGQRLFGFQPEPFPMAS
What is the function of this protein?
Transcription factor that binds to DNA at the consensus sequence 5'-CAG[GC]TG-3' (PubMed:33712461).  Dimerization with TCF3 isoform E47 may be required in certain situations (By similarity).  Binds to gene promoters and enhancer elements, and thereby regulates a transcriptional program of retinal ganglion cell (RGC) determinant genes (PubMed:33712461).  Although the exact mechanism is not certain, retinal transcription regulation by ATOH7 has a role in RGC determination and survival, photoreceptor population development, targeting of RGC axons to the optic nerve and development of the retino-hypothalamic tract (PubMed:11493566, PubMed:11156601, PubMed:12451142, PubMed:33712461).  Binds to its own promoter and enhancer sequences, suggesting autoregulation of ATOH7 transcription (PubMed:33712461).  Required for retinal circadian rhythm photoentrainment (PubMed:12451142, PubMed:26392540).  Plays a role in brainstem auditory signaling and binaural processing (PubMed:17977745).
What are the official names of this protein?
Transcription factor Atoh7, Atonal bHLH transcription factor 7, Helix-loop-helix protein mATH-5, mATH5, Protein atonal homolog 7.
What are the subcellular locations of this protein?
Nucleus. Perikaryon. Cell projection, axon.
Protein: YH73_SCHPO
Sequence: MKKQFLVRKNSSNSRYLRRDCVICLQKDGLRAQLSPCGHDQFDYSCICRWMDQSLTCPICKRHVDCVFYGFHGSSLYKKWYTQSLGSNQYSISRQLLRQPSFSSSENTDRLADLLRVRRFIYQKAWKSYENPSLSSHRQYQIPTPIQLASSASLLKKVESFIAKELLLFEYLDGHQINFIQIFLMGLLRVQNIQHPQTIDELAEFIGHEESSILLHELQRYLQFRPLSISSYLYSKRYLYGPEGLTMVQLLSQIENIQHESGPETENS
What are the official names of this protein?
Uncharacterized RING finger protein C16G5.03.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus.
Protein: PURA_LACP3
Sequence: MGTVVIVGTQWGDEGKGKITDFLSQGAKVVSRYQGGDNAGHTIHANGEVYKLRLVPSGVLYPHQLSVIGNGVVVNPKSLVGELARLAEQGVTGENLRISDRAHVILPYHIKLDKLQEAAKGADKIGTTNRGIGPAYMDKAARVGIRMADLLDKEIFEERLKANLKAKNEEFVKVYDSTPMNFDDIFEEYYQYGQQLKQYVCDTSIVLNDAIDKGEHVLFEGAQGIMLDIDQGTYPFVTSSNPAGGVTVGAGVGASKIDRVVGVAKAYTSRVGDGPFPTELLDKTGDFIRNAGHEFGTVTGRPRRIGWFDAVVVRHSRRVAGITDLCLNSIDVLTGLDKVKICVAYERDGERVENYPASLKFLSECKPVYEELPGWQEDITKAKTLDDLPENARRYVERITELLGVDLLTFSVGPDRDQTNVLENVWDKVSR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_MAGMM
Sequence: MSSGLPTLERSIELFSRLPGVGRKSAQRMVYHLLKEGGREATLLGQGLLALSERIHFCEVCHNLAEEGLCAICQDSKRDHGLICVVEEPVDVLAMERAGAYRGLYHVLGGRLSPMDGIGPDALYLDALLERLQQGGVRELIIATNPTVAGEATAHYITQLAQPLTIDISRLAYGMPMGGELEYLDESTLFQALQGRRGVL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.