PharMolix/UniProtQA huggingface dataset:
Protein: Y2214_CLONN
Sequence: MEDRIKISILMDYYRELLTEKQKYVMELYFNQDLSLAEISELTNTSRQAIYDIIKRCNKLLVDYEKKLNLARKNKELIKAKQIIIEKINDLEYSNNKNDFKNSLEDIKNTIVQYI
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein NT01CX_2214.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: TF2H1_MOUSE
Sequence: MATSSEEVLLIVKKVRQKKQDGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSNESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATDSSTSSHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAETVPHNMTEKEFWTRFFQSHYFHRDRLNTGSKDLFAECAKIDEKGLKTMVSLGVKNPMLDLTSLEDKPLDEGYSISSVPSTSNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQQAQNGQNGEPSSVDGNSGDTDCFQPAVKRAKLQESIEYEDLGNNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIINSFQSIRQEMEAYTPKLTQVLSSSAASSTITALSPGGALMQGGTQQAVNQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQYLSTNLVSHIEEMLQTAYNKLHTWQSRRLMKKT
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
What are the official names of this protein?
General transcription factor IIH subunit 1, Basic transcription factor 2 62 kDa subunit, BTF2 p62, General transcription factor IIH polypeptide 1, TFIIH basal transcription factor complex p62 subunit.
What is the protein family that this protein belongs to?
Belongs to the TFB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YTHB_BACSU
Sequence: MEISTDALIAISIIWGFVFIYAVMATMDFGAGFWSMIYLNKEHMKATDIANRFLSPTWEVTNVFIVAIVVALFSFFPGATFVLGTVLLIPGSMILLLLAIRSGFLVFSNTAKERKTLRYISGISGFIIPAILILVLPVTHGGFIEKTDGIYNLNMSKIFSSPNAYSFIGFAILSTLFLSSLLLADFSNVAEEQDAYRAYRKSALITGPISLLFAVCIMVTMRNEANWLYSGMMNDFSWIIASFITFVIAGIALFLPNKSFGQNIGKPRLALVAIGIQYFLASYAYGRAHLPYMIYPDVTVMSGFTEPATFRALFATYIVAFIILFPGFFFFWKMFMRDKRYIRQEE
What is the function of this protein?
May have a role in sporulation.  Can compensate for the loss of cytochrome aa3.
What are the official names of this protein?
Putative cytochrome bd menaquinol oxidase subunit II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL1_PSEF5
Sequence: MAKLTKRQKAIAGKIEAGKAYNFVEAAALLTELSTVKFSESVDVAVNLGVDPRKSDQVVRSATVLPHGTGKTVRVAVFTQGPAAEAALAAGADRVGMDDLAAEMKGGDLNYDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPDVASAVKNAKAGQVRYRTDKNGIIHTSVGKVGFDAVKLKENVEALIADLKRIKPASSKGIYVKRVTLSTTMGPGLVIDQGSLDV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: WHIA_CORU7
Sequence: MALTADVKDEIARVSVVRAEDMNAEVAALLRYSGALHLVAGQIVVESEVDSSATARRLMEFVEQLYHHEAQLQIIGAGNLRKSARYIVKWIKGGTEIARRTGLIDRAGRPVQGLPRTIIGGPKSACVAAWRGAFLARGTLTEPGRSCALEVATPSNEAALALVGAGRRIGVTAKTRETRGVHRVVVKDAESISALLTLMGAQATRLVWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARADRALEILGEDVPTHLAEAGQLRVKHRQASLEELGQLASPPMTKDAVAGRIRRLLSMADKRAEELDIPDTHAAVTEDLFQDVE
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: TRMD_BURL3
Sequence: MNQVTESAVQFDVVSLFPEMFRALTDWGITSRAVKQGRFGLRTWNPRDFTTDNYRTVDDRPYGGGPGMVMLARPLEAAIDAAKAAQAEQGIASTRVVMMSPQGAPLTHDRAVRMAQEPGVVVLCGRYEAIDQRLLDRCVDEEISLGDFVLSGGELPAMAMMDAVVRLLPGVLNDSLSAVQDSFADGLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIERWRRQEALRNTLRKRPDLIVRARREKLLSRADEAWLANLAREAKDAS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_CORDI
Sequence: MFLGTYTPKLDDKGRLTLPAKFREELAGGLMVTKGQDHSLAVYPREEFAARARKAAAVSRTNPEARAFIRNLAASADEQRPDGQGRITLSAAHRTYAGLSKECVVIGSVDFLEIWDAAAWAAYQEETEAAFSSAEGEFLGDFL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MURE_LACDB
Sequence: MNISLNTCILILKEHHLLKSSAVQDTVQTIMEAVSYDSRDVQNNSLFFCKGAGFRPTYLTMAKENGAIAYVAEQPYPEGTGMHALIVRNVSKAMALLSAAFYSFPQDDLFLVGFTGTKGKTTSAYFLKGMLDQLNGGRTALLSSVDNILGPAPEDTFKSSLTTPESLDLFRDMRRAVDNGMTHMVMEVSSQAYKKSRVFGLTYDLGFFLNISPDHIGVNEHPNFEDYLHCKLQLLVNSRKCIINAETDRFADVYAAATTTTNPDSIYLFARDGFENPDLKKPIDFRYKSVETDLAETKFTLTTASSKAHKLPISGEYTLQMIGDFNETNATGAIIGAGLAGMSYEDCAKGIRHVTIPGRMETVTTQKHGLIVVDYAHNKASMLALMRFMRREFTTPRVIVVVGAPGDKGISRRPGFSESLTAEADKAYLTTDDPGFENAQDICEEIDAGIDHSKCETVIELDREKAIKEAISEAGPDDVVLLCGKGADAFQKIRGVDTPYAGDIVIARQVIQELEK
What is the function of this protein?
Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramyl-tripeptide synthetase, UDP-MurNAc-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_CROS8
Sequence: MRKIIHVDMDCFFAAVEMRDNPALRDIPLAIGGSRERRGVISTANYPARKYGVRSAMPTAMALKLCPHLTLLPGRFDAYKEASAHIREIFSRYTSLIEPLSLDEAYLDVTHSPHCYGSATLMAKEIRQTIFDELQLTASAGIAPIKFLAKIASDLNKPNGQYVITPEEVPGFLRTLPLGKIPGVGKVTAAKLESLGLRTCEDVQKSDLAALLKRFGKFGRVLWERSQGIDDREISSDRQRKSVGVERTLAEDIHEWAECEAIVELLYPELERRLAAVQPDLRIARQGVKLKFNDFQLTTQEHVWPKLNKEDLLATARKTWEERRSGRGVRLVGLHVTLLDPQIERQLVLGL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSZ1_PYRWO
Sequence: MSLEESPKRKIRCPEVQVPQSNIDEELEKIVEQIKARIYVVGVGGAGCNTVNRMMEVGVTGAKIIAVNTDAQDLLKVKAHQKILIGKELTRGLGAGNDPKIGEEAAKESERELRDALEGADMVFITCGLGGGTGTGAAPVIAEIARKMGELTVSVVTLPFTMEGIRRAKNAEYGLKRLVKYSDTVIVIPNDKLLEVAPKLPIQMAFKVADEILVQAVKGITELITKPGLVNLDFNDVRAVMKDRGVAMIGIGESDSEKRALEAAEQALNSPLLDVDISGASGALIHISGADVKLEEAQQIIEYVTRNVDSKAQVIWGIQLEPELEKTIRVMVVITGVTSRYITPEEETPLETPEESPSIEISIPEL
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ 1.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: RS17_DESVM
Sequence: MSEELMNRKGRVLTGIVVSDKNDKTIVVRVETLVQHPLLKKYVRRRNKFTAHDPQNECGIGDKVKIIEYRPLSRNKRWHLVSILEKAV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: EVA1B_MOUSE
Sequence: MDAPRRDMELLSNSLAAYAHIRANPESFGLYFVLGVCFGLLLTLCLLVISISCAPRSRPRTPAPRRDPRSSTLEPEDEDDEEDEDTMTRLGPDDTLQGQELSTEPDGPLSVNVFTSAEELERAQRLEERERILREIWRTGQPDLLGSGTLGPGATATLGRMHYY
What are the official names of this protein?
Protein eva-1 homolog B, Protein FAM176B.
What is the protein family that this protein belongs to?
Belongs to the EVA1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CSCL1_ARATH
Sequence: MATLQDIGVSALINLFGAFLFLIAFAVLRIQPINDRVYFPKWYLTGERNSPRRSDRTLVGKFVNLNYKTYFTFLNWMPQAMKMSESEIIRHAGLDSAIFLRIYTLGLKIFAPVMVLALVVLVPVNVSSGTLFFLKKELVVSNIDKLSISNVQPKSSKFFFHIAVEYIFTFWACFMLYREYNNVAIMRLQYLASQRRRPEQFTVVVRNVPDMPGHSVPDTVDQFFKTNHPEHYLCHQAVYNANTYAKLVKQRAKLQRWFDYYVLKHQRNPHKQPTCRTGFLGLWGKRVDSIEYYKQQIKEFDHNMSLERQKVLKDSKLMLPVAFVSFDSRWGAAVCAQTQQSKNPTLWLTSSAPEPRDIYWQNLAIPFISLTIRKLVIGVSVFALVFFYMIPIAFVQSLANLEGLDRVAPFLRPVTRLDFIKSFLQGFLPGLALKIFLWILPTVLLIMSKIEGYIALSTLERRAAAKYYYFMLVNVFLGSIIAGTAFEQLHSFLHQSPSQIPRTIGVSIPMKATFFITYIMVDGWAGIAGEILRLKPLVIFHLKNMFIVKTEEDRVRAMDPGFVDFKETIPSLQLYFLLGIVYTAVTPILLPFILIFFAFAYLVYRHQIINVYNQQYESCGAFWPHVHGRIIASLLISQLLLMGLLASKKAADSTPLLIILPILTLSFHKYCKHRFEPAFRQYPLEEAMAKDKLEKETEPELNMKADLADAYLHPIFHSFEKEVELSSSSSSEKETHQEETPEVRVDKHETQSSSPVTELGTSSHHHHVYNSTSPSSHYASAYEQSSSQYEYHYNTHQYEEHEYRYN
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel.
What are the official names of this protein?
CSC1-like protein At1g32090.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: BSHC_FLAPJ
Sequence: MPTDCISYQKSGYFSKLIVDYLDKKPELKELYNYFPSIENFKHQIEEKNHNFKNNDKRKILVDALKKQYTNFEISELTQKNIVLLENEKTFTITTGHQLNLFTGPLYFLYKIVSTINLCKELKRNYPEYNFVPIYWMATEDHDFEEINHFNFKGKKLSWNTASKGAVGRLSTKSLTNFFTVFKAELGLSNNAEYIKKLFSDSYLQHSNLADATRFLANKLFGKYGLVILDGDAAALKKQFIPYIKDELLYQNSNKKVLESIAKLKDYSIQVNPREINLFYIEANLRERIIYENGNYKVNNTFISFSETEILKLVDANSEKFSPNVILRPLYQEVILPNLAYIGGGGEIAYWLELKAMFDFHKVTFPILLVRNSAVLINEKQEKNRQKLNITWQELFLKQQVLIDAKTKEYSEIKIDFSEQKAHLKKQFEALHQIALKTDKSFSGAVKAQEKKQTKGLDNLEKRLLKAEKKMHSEKLKKIIELQNNLFPNESLQERKSNFSEIYVEIGEELINKISDQLHPLAATFSIIKHA
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: H1612_CYRHA
Sequence: MNTVRATFLLVFVLAVSLGQADKDENRMEMQEKTEQGKSYLDFAENLLLQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1a, U11-TRTX-Hhn1a, Hainantoxin-XVI.12, HNTX-XVI.12, Peptide F4-19.87.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MIDN_DANRE
Sequence: MDQHPSARSCSSRGAAPSCESVSGEPPMNLYIHSTTGTRFELSLPAEETVEGLKRRLSQRLKVPKERLALLHKETRLSSGKLQDLGITDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQPSGGPQLQHRHLISRGSSEGTTGLSHGASGSASGMARVSHNPHPHHPHQHPHHPNTTLPSNPAAFPPSPSIPSIPPMYSTSASGHCSPPPQPSQLPGSFLHSQQPSSACAPSPSSPSPAASCPEASCSAKTSGNCNTPLRSRKPGAIIESFVNHAPGVFSGTFSGTLHPNCQDSTGRPRRDIGTILQILNDLLSATRHYQGMPPSLTQLRYQTQCTSPNSPAPSPPPSPPHTTGLTGLPTTVPSETQPTLHPLVQCQSQIRMCKPPGDRLRQTENRATRCKVERLQLLMQQKRLRRKARRDSRAPYHWLPNRKAGRSNSNSSMSSEGSLDLDFEDSVWKPDVKADMKSEFIMA
What is the function of this protein?
Facilitates ubiquitin-independent proteasomal degradation of polycomb protein CBX4.  Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion.
What are the official names of this protein?
Midnolin, Midbrain nucleolar protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Nucleus, nucleolus. Note=Detected in the nucleus and nucleolus with no expression in the cytoplasm. However, a later study finds expression in the nucleus and cytoplasm with no expression in the nucleolus.
Protein: NU4M_DROYA
Sequence: MLKIILFLLFLTPVCFINNMYWMVQIMLFFISFIFLLMNNFMNYWSEISYFLGCDMLSYGLVLLSLWICSLMLLASESINKYNNYKNLFLLNIVILLLLLVLTFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGVYLLFYTLLVSLPMLIGIFYVMNKTGSMNFYLMNNFMFNYDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGLLRVINFLQLMNLKYSFVWISISLVGGVLMSLVCLRQTDLKALIAYSSVAHMGIVLAGLLTMTYWGLCGSYTLMIAHGLCSSGLFCLANVSYERLGSRSMLINKGLLNFMPAMTLWWFLLSSANMAAPPTLNLLGEISLLNSIVSWSWISMIMLSFLSFFSAAYTLYLYSFSQHGKLFSGVYSFSSGKIREYLLMLLHWLPLNLLILKSESCILWL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PANC_MAGMM
Sequence: MESLQDRAALLAWRKRQGHQNIGFVPTMGCLHEGHLTLLREARQRCEQVVVSIFVNPTQFGPNEDFDLYPRTFEADWALLEAEGCDALFHPTVAAIYPPENPNLTHVTLPALAGMLCGAVRPGHFDGVATVVTLLLNLVRPTSAFFGLKDYQQFTVLRSMVQDLAMPVEVIGIPTVREPDGLAMSSRNRYLDAPARAQAVALSQGLNRAYHAYQEGLHDATALAHLVEQTLRQAGIARIDYVAVRDALTLQPWQGKGAPVVLIAAHVGAARLIDNLVLGAQPIPSVTQE
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_STRP7
Sequence: MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEVAYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVAKINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQGVGIKVDVNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LACR_STAAS
Sequence: MNKHERLDEIAKLVNKKGTIRTNEIVEGLNVSDMTVRRDLIELENKGILTKIHGGARSNSTFQYKEISHKEKHTRQIAEKRFIAKKAASLIEDGDTLFFGPGTTVELLAEEVNHHTLTIITNCLPVYKILLEKQTAHFRVYLIGGEMRHITEAFVGEMANAMLEKLRFSKMFFSSNAVNKGAVMTSTLDEAYTQQLALSNSIEKYLLIDHTKVGKEDFTSFCQLNELTAVVMDYEDEEKVETIKTYIEVVD
What is the function of this protein?
Repressor of the lactose catabolism operon.  Galactose-6-phosphate is the inducer (By similarity).
What are the official names of this protein?
Lactose phosphotransferase system repressor.
Protein: KDTA_RICCN
Sequence: MMLLYYALSFILLPVYFIIILIRLLIGKEDIRRIQERFAIGKHRQDDSLDFMQTSANKEEFKGDTSLRTTTYTLIREDEGLGSTYKLPLEASDARRLIWINAASIGESMVALTLIHNISKRYPDVRFLVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIFTRKFLRNWQPDLGIFIESELWPCTINEGAKQCKLLLVNARISDKSFKAWLQRKSFFQLILKNCSKIIVQSERDLQKFNELGVSDAVNLGNIKFANEKLPVNQEELSKLSLHLDNKRVVLFASTHPEDEEVILPIIKNLKEQFLDCYIILIPRHPERVKSIIDNCKSHNLSATAKSQNDLPVLSDDLYIVDRFGEMGLFFSVATISFIGGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDIAKGVLQNEAAIQIKNGEDLLTKLTYLLRSNNALELTTYRENALKFIKDNQKVLDEYLNVITKFL
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid transferase, Kdo transferase, Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: TKTI1_MOUSE
Sequence: MENVRREATRPSVPSGTLELYFPDHLYRNDYVSLEGPRWAPAIKQAVRWKFTPMGRDAAGQVWFTGLTNSEPGDAWYKLPRALDTPYREAHTRWHGCFQSRQRGLPPAYTQHLREMAFWDPAITAQYLNSGPRWGCMQWRDRQIRGKEFVVTRNQFGAKLPWRSDYVPLLSLPQRPRFTAQDFRQRGLQRPCPAIGQPPPAFTPAL
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.  Located at the center of the tektin bundle where may function to recruit tektins or stabilize the bundle.
What are the official names of this protein?
Tektin bundle-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: SLUR1_MOUSE
Sequence: MTLRWAMWLLLLAAWSMGYGEAFRCYTCEQPTAINSCKNIAQCKMEDTACKTVLETVEAAFPFNHSPMVTRSCSSSCLATDPDGIGVAHPVFCCFRDLCNSGFPGFVAGL
What is the function of this protein?
Has an antitumor activity.  Was found to be a marker of late differentiation of the skin.  Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin.  In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity.  In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner (By similarity).  In T cells may be involved in regulation of intracellular Ca(2+) signaling (PubMed:17286989).  Seems to have a immunomodulatory function in the cornea.  The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation (PubMed:23139280, PubMed:25168896).
What are the official names of this protein?
Secreted Ly-6/uPAR-related protein 1, SLURP-1, ARS component B.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3412_GEOKA
Sequence: MANEFRVCDDCKAPNLKTLIPRLKKLDPDAVIKIGCQSYCGPGRKKTFAFVNNRPVAALTEDELIDKIAERLKKR
What are the official names of this protein?
UPF0741 protein GK3412.
What is the protein family that this protein belongs to?
Belongs to the UPF0741 family.
Protein: IXTPA_TROWT
Sequence: MEIVFVSENENKIAEAREILLPLGFQSIFCGVTCRETGLTFTENAVLKAQAAVGSVKDVPIMADDSGICVDALNGMPGVLSSRWSQDGRNIDLLLWQMRDVPDVHRTAHFVCSIACVMPNTEVRTVSSVWHGRILHAPDGTGGFGYDPVFLPDGYSVSAAGLGSDLKNRISHRYKALRLMSSLLKRTYFSCHA
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: PROF1_MAIZE
Sequence: MSWQTYVDEHLMCEIEGHHLTSAAIVGHDGATWAQSTAFPEFKPEEMAAIMKDFDEPGHLAPTGLILGGTKYMVIQGEPGAVIRGKKGSGGITVKKTGQSLIIGIYDEPMTPGQCNLVVERLGDYLLEQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-1, Pollen allergen Zea m 12, ZmPRO1.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: THIM_YERE8
Sequence: MMDLFPDALASACLQQFRATPPLVHCLTNEVVQSFTANVLLALGAFPAMVVEPQEAAQFSTMANSLLINIGTLHRARAESMLSAITAANQAGTPWVLDPVAVGGLAYRTDFARHLLTLKPAAIRGNASEIMALSGMATMGRGVDSVDTSLAALPAARQLAQRTQTVVAVTGEVDYITDGQRDVAVTGGDKLMTRVVGTGCALSAVVAAFCALEGDRLHHVATACRIMSQVGGQVSQHVAGPGSFVPAFLDGLYQLETLTY
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: NUOH_BACC3
Sequence: MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRFGLLQTVADVLKLLLKEDSIPKAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVGLLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMISYEIPLVMSVIGIVLLAGSLNLNEIVAAQENVWYIFVQPIGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWAFFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPRIRGDQLMEFGWKVLLPIALANIFLTALIKELFF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LUXS_YERPP
Sequence: MPLLDSFTVDHTIMKAPAVRVAKTMKTPHGDEITVFDLRFCVPNKEVMPEKGIHTLEHLFAGFMRDHLNGDGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVTDQRKIPELNEYQCGTYHMHSLEEAQSIAKDILDRDVRINHNEELALPKEKLTELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.