PharMolix/UniProtQA huggingface dataset:
Protein: H2B1_MEDTR
Sequence: MAPKGEKKPAEKKPAEEKKSTVAEKAPAEKKPKAGKKLPKEGGSAAGEKKKKRSKKSVETYKIYIFKVLKQVHPDIGISSKAMGIMNSFINDIFEKLAQESSRLARYNKKPTITSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Probable histone H2B.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: UTP10_MAGO7
Sequence: MATSLAAQLAQIAAKSRSSLNVKAQKAAHTKSLIFEPRIAAGQSYQTIYTACRDGFEELCQLDARFTPFSNTLFSEQSQDEDRSQMTQAENKELDRRVDSFLRLVGSRLRLMPAIKAIEWLIRRFRIHEFNTSTLLATFLPYHSIPAFVTLLSILPADLPQQYKFLAPYVRSLTAPPRAAIVYQATHHREFLTAITEYTLDACRNKQQYPALVSFWAGVMTEAVNGRIDINRSGRQGVQLDNDLALIALVSKPLGDAMTMKDVPDIQIAAYMVVSLLAAKANFDDKLLSVFMEQLVIGWTAETVRPGLVCLSILAQYRAPKQLSSRVAKALLKMDDLPQRLVDASKQCRVDKLAYALVLALADRLAKKGDARGLPIIKSILLLELLQEKLGKVAFKSLLRAALKMTDEVDQDGSARKQLGSTLVLLSQSAGATGVMVRQVIEDEDYDIEGLELRLDTSFGPRRLLEDKPAEEDAKDLEVRQDPKETLEAAIERLAVPPRSVKSFLSQKSDQLFDDMCKVLLSVATDPDDLLKFDEAPFLCRQTAHDDSYYFSFYMRVWCGPYPTLIRSAALEMAKRRLKQGDCAALDLQAMIPYCVAALSDPAKKVRQAAADLITVLSKSNAEGIETAKRPIWASKQLYEQSNEQTWMNPAASRALLQEIIVPALEESVLDEEHISNVLRSHLQSTKDSATGPQLSSAVRLSIFSCITSHVVHTPLLAVKSRLLKPTNQVDSVSKATRTSLLLPLLRWWASLSSTEAAQLCERERIDESKFNQSCVNVAVANDKPGLETLFEIITNSSAWTREGLVEAAFARTRKIWSTIKSDSKLKLALSMLDLAQTPATAGSSAEFVSEEAADFLRNVDLTTNILNAFLESLQDIPKITTDSPATKRRRTSSSDHSRGVSLQATNAVKAALNKVTFVLQLVEGSKPAEHPELLQSLFVTLADLQVLRSQVGSELGYLQNLVLSSLLAMMPTYKNNKSLKIDTSVGHGDVLVQCIQKSSSPAVQNSALLLVASLANTAPDVVLHSVMPIFTFMGGSVLRQSDDYSAHVVVQTIKEVIPPLVETFRKSRRNLVTSAAELLSSFVIAYEHIPSHRKRDMFISLIENLGPKDFLAALVAMFVDKYGTTDSMVAFCKDLMNSFGVEVQLQSLVMLLDLVSDCLQPKPTLAATLFNRNTDDDQDLHKTALKELTLLPKVLSSRQLRTEVSQLAGRDDMEASKFRELYASLLEKILTLAETVKTNKALHARCSDTLAGLLNLLSIGEFIKAVENLLDRPSISLRQKVLRTLEVRVDQESNTDADSRTVLLAFLPQLTAVIRDSDDIAYKHTAVACVDKIAEKYGKKDLEAVAAAATTIAGDCCLGQPDKRLRVMALLCLASLVDVLQDGIVPTLPVSLPKALSYLSESLQGEKEPELHNAVYSFFESLAVHVPYMLTKTYIGQLLAVSNVSAEANMSDESSQARFGCLQLLANQVDANTMLAALEQNWAQAVNAGFSAVEEYLKLLATVLDKHPSTIIAKHISTLSTIFLSALDLRRNVQSKDTVSIAALAKLTEIEALINDVALKMIYKLNDSKFRTVFTQLMEWVATGLPKDDKLGKVLRHQSVYSFLLAFFDNLKDVVASYASYIIDDATAILKASDPSKMEDRELWQLVLKTLARCFEHDSGGFWQVPAHFEAVSGLLVEQLEHAAALGELPGGDLVQNAVVGLAEAAASRDHRKELNAAVLRRLRSPSASVRLAAVRCEQSLTDTLGEDWLEMLSEMLPYISELQDDDDEDVEKETHRWITKIEAILGESLDAMLQ
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Involved in ribosome biosynthesis (By similarity).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 10.
What is the protein family that this protein belongs to?
Belongs to the HEATR1/UTP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HIS8_PECCP
Sequence: MSNIEQLARANVRALTPYQSARRLGGNGDVWLNANEYPEAPAFQLTLQTLNRYPECQPVQVINRYAEYAGVQPEQVLVSRGADEGIELLIRAFCEPGKDAILFCPPTYGMYAVSAETFGVERRTAASKADWQLDLESIEAQLDGTKVIYVCSPNNPTGNLIAREDLRQLLTMAQGNALVVIDEAYIEFCPQATTAVWLDEFPHLVILRTLSKAFSLAGLRCGFTLANPEVIQLLLKVIAPYPLSTPVADIAAQALSREGIAKMKANVEEITSARRWLSDALKDIPCIEEVFPSESNYLLVRFTASPSVFKTLWDQGIILRDQNKQPSLAGCLRITIGNRYECERVVAALQSLPGINA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: PRP38_YEAST
Sequence: MAVNEFQVESNISPKQLNNQSVSLVIPRLTRDKIHNSMYYKVNLSNESLRGNTMVELLKVMIGAFGTIKGQNGHLHMMVLGGIEFKCILMKLIEIRPNFQQLNFLLNVKNENGFDSKYIIALLLVYARLQYYYLNGNNKNDDDENDLIKLFKVQLYKYSQHYFKLKSFPLQVDCFAHSYNEELCIIHIDELVDWLATQDHIWGIPLGKCQWNKIYNSDEESSSSESESNGDSEDDNDTSSES
What is the function of this protein?
Required for pre-mRNA splicing and maintenance of stable U6 small nuclear RNA levels.  Implicated in the formation of stable and biologically active snRNP structures.  As part of the U4/U6. U5 tri-snRNP particle, dispensible for spliceosome assembly, but required for conformational changes, which result in U4 snRNA release and the subsequent catalytic activation of the spliceosome.
What are the official names of this protein?
Pre-mRNA-splicing factor 38, Pre-mRNA-processing factor 38.
What is the protein family that this protein belongs to?
Belongs to the PRP38 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYL_BORPD
Sequence: MQERYSPTAVEAAAQQDWQARDAYRVTEHARNADGTEKPKFYACSMLPYPSGKLHMGHVRNYTINDMMARQLRMRGYNVLMPMGWDAFGMPAENAAIKSKVPPAKWTYDNIAYMKKQMQAMGLAIDWSREMCACDPEYYKWNQWLFLKMLEKGIAYRKTQVVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPGYYLRITDYADELLDQVRSGLPGWPERVRAMQENWIGKSEGVRFAFPHTIAGADGQLIQDGRLYVFTTRADTIMGVTFCAVAPEHPLATHAAATNPELASFIEQCKLGGTTEAEIATREKAGMRTGLTVTHPLTGAPVDVWVGNYVLMSYGDGAVMGVPAHDERDFAFAKKYQLPIRQVVAHEGKAYSTDAWQEWYGDKQGGRTVNSGKYDGLPYAEAVDAIAADLAAQGLGEKQTTWRLRDWGISRQRYWGTPIPIIHCADCGPVPVPEQDLPVVLPDDLIPDGSGNPLAKNEAFLSCSCPRCGKPARRETDTMDTFVDSSWYFMRYTSPGNDQAMVDARNDYWMPMDQYIGGIEHAVLHLLYARFWTRVMRDLGLLKFDEPFTKLLCQGMVLNHIYSRKNAQGGIEYFWPEEVENLYDAKGAITGARLKSDGSDVNYGGVGTMSKSKNNGVDPQALIDTLGADTARLFVMFASPPEQTLEWSDSGVEGANRFLRRLWSHCHAHRDAVARGLAAGADWAQAPAPVKDLRREVYGLLKQADYDYQRIQYNTVVSACMKMLNAIDDAKLPEGAHADAARAETLGVLLRVLYPVVPHVTWLLWRELGYTHSLGDLLDAPWPHVDEAALVADEIELMLQVNGKLRGAIRVAAKASKADIEQIAAAQEEVARFLEGRPPKRVIVVPGKLVNVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_SHIDS
Sequence: MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: XYNR_ECOLI
Sequence: MPIIQSVERALQILDLFNEQATELKITDISKLMGLSKSTLHSLLKTLQLHGYIDQNPENGKYRLGMKLVERGHFVVGSIDIRQKAKGWLTELSRRTGQTTHLGILDGREGVYIEKIEGKLAAIAYSRIGRRLPVHATAIGKVLIAWLGEAELNALLEGYQYTTFTPATLASREALMSALAQTREQGYALDSEENEQGVRCVAVPVWNHESRVIAALSLSTLTSRVDDAELANFREQLQQAGLALSRALGYPA
What is the function of this protein?
Involved in regulation of xylonate catabolism.  Represses the expression of both yagA and yagEF operons.  Binds mainly at a single site within the spacer of the bidirectional transcription units yagA and yagEF.
What are the official names of this protein?
HTH-type transcriptional regulator XynR, Regulator of xylonate catabolism.
Protein: RL13_ALKCK
Sequence: MRTTYMAKPNEVERKWYVVDAEGQTLGRLASEVASILRGKHKPTFTPHVDTGDHVIVLNASKIQLTGNKLQDKIYYRHTNHPGGLKQTKAQDMRANKPERMLELAIKGMLPKNTLGRKQGMKLHVYAGSEHNHHAQKPEAYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: SYGB_PSE14
Sequence: MSAQDFLVELGTEELPPKTLVSLADAFLAGIEKGLSGAGLTYSAKQVYAAPRRLAVLITALATQQPDRSVNLDGPPRQAAFDADGNPTQAALGFAKKCGVDLSEIDQSGPKLRYSQTILGKPTTSLLPTIVEDSLNDLPIAKRMRWGARKEEFVRPTQWLVMLFGDQVVDCTILAQSAGRHSRGHRFHHPQDVRISSPAGYLSDLRAAHVLADFNERRQIISKRVDELATQQEGTAIVPPSLLDEVAGLVEWPVPLVCSFEERFLEVPQEALITTMQDNQKYFCLLDAEGKLLPRFITVANIESKDPAQIVAGNEKVVRPRLTDAEFFFKQDKKQKLETFNDRLKNVVFQAQLGSVFDKAERVSKLAAYIAPRIGGDAQRAARAGLLSKCDLSSEMVGEFPEMQGIAGYYYAKADGEPEDVALALNEQYMPRGAGAELPTTLTGAAVAIADKLDTLVGIFGIGMLPTGSKDPYALRRAALGILRILIEKKLDLNLVETVKFAVTQFGAKIKPAGLAEQVLDFIFDRLRARYEDEGVDVAVYLSVRALQPASALDFDQRVQAVQAFRKLPQAAALAAVNKRVSNLLSKAEGSIAQTVEPKYFDNANEFSLYSAIQQADHAVQPMAAERQYSESLARLAMLREPVDAFFEAVMVNAEDANVRANRYALLSRLRGLFLGVADISLLG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1C04_GORGO
Sequence: MRVMAPRTLILLLSGALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVNLRKLRGYYNQSEDGSHTLQSMYGCDLGPDGRLLRGYSQFAYDGKDYIALNEDLRSWTAADTAAQVTQRKWEAARVAEQERAYLEGLCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLPEPLTLRWEPSSQPTIPIVGIVVGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSDESLITCKA
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
Class I histocompatibility antigen, Gogo-C*0203 alpha chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CRLS1_HUMAN
Sequence: MLALRVARGSWGALRGAAWAPGTRPSKRRACWALLPPVPCCLGCLAERWRLRPAALGLRLPGIGQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD
What is the function of this protein?
Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG).  CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
What are the official names of this protein?
Cardiolipin synthase (CMP-forming), CLS, Protein GCD10 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RPOZ_STAAW
Sequence: MLNPPLNQLTSQIKSKYLIATTAAKRAREIDEQPETELLSEYHSFKPVGRALEEIADGKIRPVISSDYYGKE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: Y1967_STRT2
Sequence: MIRFLIPTAKEMKPSKEVPSQKLSEKSEAILTEMAKLSTDDLSIAYKIKPEQAEKEKQRWDAILAGEAKNYPAVELFNGLMYRHIKRKDLSTCEKDFLSHQVFITSSFYGIIPAFYPIQEHRHDFHTKVKVNGQSLKNYWRAEYDQFLEEGQVPVVSLLSSEFEDVFSPSLRKQLFTVSFMEDRNGILKTHSTISKKARGAFLTAVMEESCQTIDALRDLSFDDFYYRKDLSSDSELFFVRKVKKV
What are the official names of this protein?
UPF0246 protein stu1967.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: PDXT_PYRHO
Sequence: MKVGVVGLQGDVSEHIEATKMAIEKLELPGEVIWLKRPEQLKGVDAVIIPGGESTTISRLMQRTGLFEPIKKMVEDGLPVMGTCAGLIMLAKEVLGATPEQKFLEVLDVKVNRNAYGRQVDSFEAPVKLAFDDEPFIGVFIRAPRIVELLSEKVKPLAWLEDRVVGVEQENIIGLEFHPELTNDTRIHEYFLRKVI
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: PCH2_XENTR
Sequence: MDEVAVDLKQALPNVYNNLQVHVDVHQKSNSPATSQDIQSHVMQLLNRHCVVFGDYSWTEFDDSFLMKNIHSISIADTELKLKDRQPIDLSKCKVLIHIFQLNEDGPCVESLEEENEDLVAANHWLLPAADFHGLWDSLIYDSEIKSRLLDYIETAMLFSDKNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSYRYRYGQLVEINSHSLFSKWFSESGKLVTKMFQKIHELINDKEALVFVLIDEVESLTAARKASRAGTEPSDAIRVVNAVLTQIDHIKRYPNVVILSTSNLTEKIDVAFTDRADIKQYIGPPSPAAIFKIYLSCIEELMKCQIIYPKQQLLTLRDLEIIGFLENNISKLSLQLNEISRKSEGLSGRVLRKLPFLAHALYLQSPTVTIERFLWALSLAVDEQFQERKNFSENI
What is the function of this protein?
Plays a key role in chromosome recombination and chromosome structure development during meiosis.  Required at early steps in meiotic recombination that leads to non-crossovers pathways.  Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways (By similarity).
What are the official names of this protein?
Pachytene checkpoint protein 2 homolog, Thyroid hormone receptor interactor 13 homolog, Thyroid receptor-interacting protein 13 homolog, TR-interacting protein 13 homolog, TRIP-13 homolog.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. PCH2 subfamily.
Protein: RK2_SACOF
Sequence: MAKHLYKTPIPSTRKGTVDRQVKSNPRNKLIHGRHRCGKGRNARGIITARHRGGGHKRLYRKIDFRRNQKDISGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTKVPISMGNALPLTDMPLGTAIHNIEITRGRGGQLARAAGAVAKLIAKEGKLATLRLPSGEVRLVSQNCLATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGKAPIGRKKPTTPWGYPALGRRTRKRKKYSDSFILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRB_FINM2
Sequence: MLKNRNLINADDFNVEEINEILNLAEEIIKSPSDFSNLCNGKILGTLFFEPSTRTRLSFESAIHRLGGDCIGFSESASSSTSKGESLADTIRTVSNYTDIIAMRNPKEGSAVLASSYAEVPLINAGDGGHQHPTQTLTDLLTIWMTKKKLDNMTIGLCGDLKFGRTVHSLIKAMSRYENNKFILISPEELQVPDYIKMFLKSKNIEFKEVEKMEDVIGELDVLYMTRVQKERFFNEADYVRLKDSYILDNDKMKLATEDLAVLHPLPRVNEIATEVDSDPRAVYFKQVRYGVIVRMALILKLLGVR
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PLSY_PARP8
Sequence: MENLIVAVVAYLIGSVSFAVIVSAAMGLADPRSYGSKNPGATNVLRSGNKKAAILTLIGDAFKGWLAVWLTGHFSAHFGLDDTSVAIAAIAVFLGHLYPVFFRFKGGKGVATAAGVLLAINPILGIATLLTWLIVAFFTRYSSLAALCAAIFAPLFDGFLFGANVIALSIVAMSALLIWRHRANIAKLVAGQESRIGDKKKAEAAASHKH
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPEA_SYNR3
Sequence: MVVAPSQVEQQNWTPAASAQLYGLDQWGDPYFSVNARGHVLVQPRGDRGGSLDLVELVEGLQSRDLQLPLLIRFEDILEDRLERLHGAFERAIAQYGYGGHYQGVFPVKCNQQRHVVEQLVESGRRWHFGLEAGSKAELLIALSLLDDPKALLICNGYKDQRYIETAILARQLGRQPVVVIEQADEVPRIIEASRNLGAAPLIGVRAKLSTRSTGRWGSSVGEKAKFGLSIPDLLATVEALRDADLLGDLRLLHFHVGSQICDIAVLKDALQEAGQLYVQLASLGAPMGFLDVGGGLGVDYDGSRSATAASTNYSLQNYANDVVATIRECCEPQGIVVPTLVSESGRAIASHFSVLVFNVLGQSGVNQPSIPEAVEGEALIVRNLRETLSGIGPDNLQEAWNDALKFKDDALAAFRLGYLSLTERGKAEQLYWACCSAIADLLPGEEELPDELKGLKAAFASTYYANLSVFRSAPDTWAIDQLFPVMPIHRLEEQPRELGSFADLTCDSDGKLARFIASGSAKPLLELHELKDGEPYWIGLFLGGAYQEVMGNLHNLFGSTNAVSIRLSPGGPYRVEHVVRGQTNSDVLEAMEHNPEALLERLRQASEEAIGSGDLSISAARRLMQHLEGSLRQTTYLEE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: CCME_ALTMD
Sequence: MNPRRKQRLAVVGIIGFLIVSAVGLMLYALNDSIDLFYTPSEIIEGKNGQKPQIGQRLRIGGMVVPGSVSRDSESLAVSFDLIDTGPTVTVTYTGILPDLFREGQGIVATGVLTDVGAIKAQEVLAKHDEEYMPPELAEKMKGIKHVKPENMPTYESSNGAGSK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RS20_LEPBL
Sequence: MANIKSSEKDIRRTKRRNAANSQNRSRLRTQAKKILKAIKEKDPKAAMALFIEYTSFLDKAAKTNLIHSKNADRKKSRMAKRLNAVSAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MENG_PORGI
Sequence: MQSPERITPYDTECPKNEQVEAMFNHIAGHYDRLNHLFSWGMDRVWRQKAIRMIEPFAPHTVLDVATGTGDLAIEICRHIPSVKQVTGVDLSLEMMRIGEQKVRSENLDNRITFMQKDCLDLPFADHSFDAVTVAFGLRNFQNIKLGLEEMYRVLNEGAPLMILELSRPVSFPWKQGYNFYASHVIPVVGRFLSQDAEAYTYLPESIAAMPQREELADLMLSVGFREAYYRSLSLEVATVYMGLK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: GRE3_YEAST
Sequence: MSSLVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISALNANIRFNDPWTWLDGKFPTFA
What is the function of this protein?
Aldose reductase with a broad substrate specificity.  Reduces the cytotoxic compound methylglyoxal (MG) to acetol and (R)-lactaldehyde under stress conditions.  MG is synthesized via a bypath of glycolysis from dihydroxyacetone phosphate and is believed to play a role in cell cycle regulation and stress adaptation (PubMed:11525399).  In pentose-fermenting yeasts, aldose reductase catalyzes the reduction of xylose into xylitol.  The purified enzyme catalyzes this reaction, but the inability of S. cerevisiae to grow on xylose as sole carbon source indicates that the physiological function is more likely methylglyoxal reduction (Probable) (PubMed:11722921).
What are the official names of this protein?
NADPH-dependent aldose reductase GRE3, AR, Genes de respuesta a estres protein 3, NADPH-dependent aldo-keto reductase GRE3, Xylose reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MURD_THEVB
Sequence: MPTVHVIGLGRSGIAAARLLKRQGWQVEVSDRRQTPALQSQQQLLQAEGIPVQLNYDFDLQTLISVGLRVPDEIVISPGVPWHSPALVAARQAGIPVRGEVAIAWQTLAHLPWVCITGTNGKTTTTALTAAIFQAAGYNAPACGNIGNSICEVALTARALDWVIAEISSYQLESSPPLQPEFALWTTLTPDHLERHGTLDAYVATKAHLMNGAKHVILNGDDPYLRQHMVNRWPQAWWISTQGAIALPKGIAQGIYIAEDQVWFQDQPLLPTHILQMPGRHNQQNFLLAVATAHLAGIPAETIAKGVAGFAGVPHRLERIRQWREVEWINDSKATNYDAAEIGLRSVTGPVILIAGGQAKKGDDRPWLNLIQEKAAWVLLIGEAAPQFAQRLEAIGFTNYEIMETLDRAVAAAAELVTQYPIKTVLFSPGCASFDQYQNFEERGDHFRQLCLEL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4M_PHOSU
Sequence: MLKIIIPSIMLIPLTWFSNNKKVWINVTSYSFVINMIALVTLWQVNDITTNFSTMFSTDSLSSPLTMLTIWLLPLMLLASQKHIKNQTDFNKKMYISLLITLQVLLIMTFSANELIMFYILFEATLIPTLIIITRWGNQAERLNAGLYFLFYTLIGSIPLLIALISIQNTLGTLNIMLLSLDSSPQTPTWSSHILWLACIMAFMIKMP
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NUP1_ARATH
Sequence: MASAARGESSNPYGGGLGTGGKFRKPTARRSQKTPYDRPTTSVRNAGLGGGDVRGGGWLSKLVDPAQRLITYSAQRLFGSLSRKRLGSGETPLQSPEQQKQLPERGVNQETKVGHKEDVSNLSMKNGLIRMEDTNASVDPPKDGFTDLEKILQGKTFTRSEVDRLTTLLRSKAADSSTMNEEQRNEVGMVVRHPPSHERDRTHPDNGSMNTLVSTPPGSLRTLDECIASPAQLAKAYMGSRPSEVTPSMLGLRGQAGREDSVFLNRTPFPQKSPTMSLVTKPSGQRPLENGFVTPRSRGRSAVYSMARTPYSRPQSSVKIGSLFQASPSKWEESLPSGSRQGFQSGLKRRSSVLDNDIGSVGPVRRIRQKSNLSSRSLALPVSESPLSVRANGGEKTTHTSKDSAEDIPGSSFNLVPTKSSEMASKILQQLDKLVSTREKSPSKLSPSMLRGPALKSLQNVEAPKFLGNLPEKKANSPDSSYQKQEISRESVSREVLAQSEKTGDAVDGTSKTGSSKDQDMRGKGVYMPLTNSLEEHPPKKRSFRMSAHEDFLELDDDLGAASTPCEVAEKQNAFEVEKSHISMPIGEKPLTPSEAMPSTSYISNGDASQGTSNGSLETERNKFVAFPIEAVQQSNMASEPTSKFIQGTEKSSISSGKPTSEEKRIPLEEPKKPAAVFPNISFSPPATGLLNQNSGASADIKLEKTSSTAFGVSEAWAKPTESKKTFSNSASGAESSTSAAPTLNGSIFSAGANAVTPPPSNGSLTSSPSFPPSISNIPSDNSVGDMPSTVQSFAATHNSSSIFGKLPTSNDSNSQSTSASPLSSTSPFKFGQPAAPFSAPAVSESSGQISKETEVKNATFGNTSTFKFGGMASADQSTGIVFGAKSAENKSRPGFVFGSSSVVGGSTLNPSTAAASAPESSGSLIFGVTSSSTPGTETSKISASSAATNTGNSVFGTSSFAFTSSGSSMVGGVSASTGSSVFGFNAVSSASATSSQSQASNLFGAGNAQTGNTGSGTTTSTQSIPFQFGSSPSAPSFGLSGNSSLASNSSPFGFSKSEPAVFTSVSTPQLSSTNSSASSSSTMSSPLFGTSWQAPNSSPNSGPVFSSSFTTSSTPTTFSFGGSSAATVSSTTTPIFGASTNNTPSPSPIFGFGSTPPTTPQQPVFGNSGTPSQSLFGNSTPGFAFGAPNNGNGINNNQQVSMEDSMAEDTDQANRASMVAPMFGQAAVSMPQPNFAFGGGAATQPPSMANPFQFGGQPMASTLQNASPFQASQSLEFQGGGSFSLGSTGGGDKSGRRIFKAKKSTRKK
What is the function of this protein?
Nucleoporin required for nuclear mRNA export.  Functions as an adapter and/or regulator molecule in the periphery of the nuclear pore complex (NPC).  May interact with importin proteins and mediate active nucleocytoplasmic transport through the NPC.  Involved in regulation of nuclear morphology.
What are the official names of this protein?
Nuclear pore complex protein NUP1, Nuclear pore complex protein NUP136, Nucleoporin 1, Nucleoporin 136.
What are the subcellular locations of this protein?
Nucleus envelope. Nucleus, nuclear pore complex. Cytoplasm, cytosol. Note=Interacts dynamically with the NPC and localizes to the cytosolic pool following nuclear envelope breakdown during mitosis.