PharMolix/UniProtQA huggingface dataset:
Protein: ADDA_STAAC
Sequence: MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: CAC3_BOVIN
Sequence: FSQPFSRPSSRVVNGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDRSVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDILPNEAPCYISGWGRLYTGGPLPDKLQQALLPVVDYEHCSQWDWWGITVKKTMVCAGGDTRSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETIASN
What is the function of this protein?
May protect procarboxypeptidase A against denaturation in the acidic environment of the ruminant duodenum.
What are the official names of this protein?
Proproteinase E, Procarboxypeptidase A complex component III, Procarboxypeptidase A-S6 subunit III, PROCPA-S6 III.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: SNX4_ASHGO
Sequence: MSEIKLGDQWFIIVSDPQKQRGDKSSSGSYVTYQISSKPATEGDKRSGEDDITVVHRRYSDFVLLYQILANDYPACIVPPLPDKKVLNYLDRFSQSFTQKRCHSLQNFLQRLAQHPVLSQSKILHTFLVSSDWDAYQKSLAETVGNLSNKEELTETIMNAFKSVHSQSDEFVEIKEKSGKLDHNVSKIDKLFHRVVKKQEAIAEDYGKLGLSLRELQELVTTGDDRNSEVGNLGTKIKTFNEGMAQLSYSLRDLSRYIDYEYIIDLRDMEDYIDSMKQLIKLKDQKQIDYEELSDYLTRSINEKNNLISGYGSGSNFFKSKLEEFTGINQEAARREKISKLESKVQALTTEVENAKKVADAFEKEALKEVEIFEQIKTRELKRSLTTLADHHIEFYQKMVNTWSKIEESL
What is the function of this protein?
Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells.  Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), autophagy, mitophagy, and pexophagy.
What are the official names of this protein?
Sorting nexin-4, Autophagy-related protein 24.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Preautophagosomal structure membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures. Associates to phosphatidylinositol 3-phosphate, necessary for peripheral membrane localization to the perivacuolar punctate structures.
Protein: ATPE_HELPY
Sequence: MALLKISVVVPEGEVYTGEVKSVVLPGVEGEFGVLYGHSNMITLLQAGVIEIETENQKEHIAINWGYAEVTNERVDILADGAVFIKKESDDRDDAISRAKKLLEDASSDRLAVSSVLAKIESL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PRL1_TRYCC
Sequence: MGANGTLVECKRGESDAVVFRFLIFDAPSPSSVTAYVKLMQKYNVRHIVRACGQTYSAEAFEKQGMVVHGWSFDDGAPPTQTVIDNWLNLLEQEKNKSPPETIAVHCVAGLGRAPILVALALVEYGGMPPLDAVGYVRGRRKGAINQVQLNWLMRYKPRHQEGNEGSLSCAGCAVM
What is the function of this protein?
Has protein tyrosine phosphatase activity.
What are the official names of this protein?
Protein tyrosine phosphatase PRL-1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Flagellar pocket. Note=In epimastigotes, localizes close to flagellar pocket, cytostome and to reservosomes. Reservosomes are prelysosomal-like acidic organelles found at the cell posterior end which contain the protease cruzipain and ingested proteins and lipids. In amastigotes and trypomastigotes partially co-localizes with concavalin A, a marker of the endocytic pathway.
Protein: CVC1_GAHVM
Sequence: MEAHIESETIYSLSNFDRGAMRHLLTHIIIPDECLSAAGIDLTNLKDASPRYTTSVYSSLSVSVGVQIRQNATGLCSNWSNVYGEYVPSGALHSLLVPQVTNPAVFSTSNQSDQGALFISLPIECDSQNRFDPFTSVALRIPCSDIRTGDYKSYKDILFTQDELVPIGTRYNNDTERLQTLFLQFLQYTKKFESELPVTIIELGAKLEACIGNVDDVIHSQSKQFDIMHLLANNKHEFDTPDIAARIEADNTEIVQLIKKAAEAITKRAPVSGSLEKGSLGVVSGLKQGAIACLKNNTDLPSKNTQQKAVMNGLEPAGKIRFVGDGNTNVRLSSAMNHQLKEITTNFEDVLMFDSPSQKPVDSKEIFLTAIGILGNGITLANLWRCGSISIVTRVHSTTKSQFYIVAYENSVALGGRSSHLTPNPTSLNILLSIACQEEGVDHPCYLSQERKIDIARQAPILSDPLLREHNQLQAFSAGSEIDLMIDFKTHISNCVISAIGEALRMEPNLYQMISYHIHAYDLPFITEITNRTPNYIRATLNAISNSSWEKFSTGALISAAISYMAGYINKFGGKAYRRYTTENAAEHLGGDYQLVNTKIPGLVLFDYYSTGGECIKLNNRPVPIILNGGVDLWNRQPYNRSVMTCTFPEWFVPHATCEKFLPGESYAYICVGYDEHLHIAIVLPAGFMLTAHTEFNWPVARIEAVLSRLCRTNKMQQVLRPYVSEVYM
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.
What are the official names of this protein?
Capsid vertex component 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RIBX_CHLAA
Sequence: MQQTLPVTRVSPRVRSLQRFEWPALGLPVTLMLLLVFWQAGVTLSGYPAFILPSPALVAGRFWQALSSGLLWQHTLATLSAALGGFTLALIIALILGYTLAHIRWLEQALAPVLAASQAIPVVAVAPLIILWFGAGLTSKVLVAALITFLPILINTVVAIRSIPRELIEMAYISGANRWQLLRYVEAPLALPVLFGGVRTGLALATTGAVVGEFVAGRVGLGALINIARGLFDTPLIFVALATLALITLTLYVLAGLLERLLVRWEAS
What is the function of this protein?
Part of an ABC transporter complex that transports riboflavin into the cell.
What are the official names of this protein?
Riboflavin transport system permease protein RibX.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IOVO_DENBI
Sequence: VATVDCSDYPKPACTLEYMPLCGSDNKTYGNKCNFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS51_PROMM
Sequence: MTACVLIVDAGLGNIGSVVAAYDRLGVRNFRIRKPPSDIACYTHLILPGVGSFSAGMDSLNSLGWSDWLKDVWLPTGRPLLGICLGMQLLASRGFEGSDSGNSIPGLDLISGKIVLMSPSQNLALPHVGWNSVYWSNTITPLSVDINSGCDFYFVHSYTFRCDDDSNCLATSNYGSQFSAVVSDISRNVWGMQFHPEKSQKLGKCLLQNFIALNPC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH 1, IGP synthase glutaminase subunit 1, IGP synthase subunit HisH 1, ImGP synthase subunit HisH 1, IGPS subunit HisH 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_JANSC
Sequence: MADTSKDIEELIGIMARLPGLGPRSARRAVLTLIKKRGALMRPLAETMARVAESARECVNCGNIGTGDLCEICMDVRRATGEICVVEDVADLWAMERGQAFKGRYHVLGGTLSALDDVGPEDLRIPKLRARMADEGITEVILALNATVDGQTTAHYIADELAPTGVTLSSLAQGVPIGGELDYLDDGTISAALRARKSL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: KEFF_SALHS
Sequence: MILIIYAHPYPHHSHANKRMLEQAGTLENVEIRSLYHLYPDFNIDVAAEQEALSRASLIVWQHPMQWYSVPPLLKLWMDKVLTHGWAYGHGGTALHGKHLLWAVTTGGGENHFAIGSHPGFDVLSQPLQATALYCGLKWLPPFAMHCTFICDDDTLQAQARQYKQRLLAWQEVNHG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FA89A_RAT
Sequence: MSGAGSAGMARGLRVDGLPPLPKSLSGLLHSAAGGAAGGWRHLERLYAQKSRIQDELNRGGAGGGGARAAGMRTKPPNLDAALALLRKEMVGLRQLDMTLLCQLYGLYESIQEYKGACQAASSLDCNYALENGFFDDDEDFQEQGSLRDGQGRGSPGDPSLPLTHLSSSDWILESI
What are the official names of this protein?
Protein FAM89A.
What is the protein family that this protein belongs to?
Belongs to the FAM89 family.
Protein: S41A1_MOUSE
Sequence: MSSKPEPKDIHQPNGTGPTPSPCSSDGPGREPLAGTSEFLGPDGVEVVVIESRANAKGIREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGQMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELKHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEPTPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD
What is the function of this protein?
Na(+)/Mg(2+) ion exchanger that acts as a predominant Mg(2+) efflux system at the plasma membrane.  Transporter activity is driven by the inwardly directed electrochemical gradient for Na(+) ions, thus directly depends on the extracellular Na(+) ion concentration set by Na(+)/K(+) pump.  Generates circadian cellular Mg(2+) fluxes that feed back to regulate clock-controlled gene expression and metabolism and facilitate higher energetic demands during the day (By similarity).  Has a role in regulating the activity of ATP-dependent enzymes, including those operating in Krebs cycle and the electron transport chain (PubMed:33153064).
What are the official names of this protein?
Solute carrier family 41 member 1.
What is the protein family that this protein belongs to?
Belongs to the SLC41A transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: KTNA1_STRPU
Sequence: MSVDEICENTKMGREYALLGNYETSLVYYQGVLQQIQKLLTSVHEPQRKHQWQTIRQELSQEYEHVKNITKTLNGFKSEPAAPEPAPNHRAAPFSHHQHAAKPAAAEPARDPDVWPPPTPVDHRPSPPYQRAARKDPPRRSEPSKPANRAPGNDRGGRGPSDRRGDARSGGGGRGGARGSDKDKNRGGKSDKDKKAPSGEEGDEKKFDPAGYDKDLVENLERDIVQRNPNVHWADIAGLTEAKRLLEEAVVLPLWMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSASLTSKYHGESEKLVRLLFEMARFYAPSTIFIDEIDSICSKRGTGSEHEASRRVKSELLIQMDGVSGPSAGEESSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPEIDGREQLLRINLKEVPLADDIDLKSIAEKMDGYSGADITNVCRDASMMAMRRRIQGLRPEEIRHIPKEELNQPSTPADFLLALQKVSKSVGKEDLVKYMAWMEEFGSV
What is the function of this protein?
Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner.  Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.  In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux.
What are the official names of this protein?
Katanin p60 ATPase-containing subunit A1, Katanin p60 subunit A1, p60 katanin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
Protein: CAS2_CHLTE
Sequence: MLVLVTYDVNTETPAGRRRLRRIAKTCQNYGQRVQFSVFECNVDPAQWVKLRSKLLNEMDPKLDSLRFYFLGSNWQGRVEHEGAKEPRDLEGTLIL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: RIPL2_HUMAN
Sequence: MEEPPVREEEEEEGEEDEERDEVGPEGALGKSPFQLTAEDVYDISYLLGRELMALGSDPRVTQLQFKVVRVLEMLEALVNEGSLALEELKMERDHLRKEVEGLRRQSPPASGEVNLGPNKMVVDLTDPNRPRFTLQELRDVLQERNKLKSQLLVVQEELQCYKSGLIPPREGPGGRREKDAVVTSAKNAGRNKEEKTIIKKLFFFRSGKQT
What is the function of this protein?
Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines (By similarity).  Plays a role in cellular protein transport, including protein transport away from primary cilia (By similarity).  May function via activation of RAC1 and PAK1 (By similarity).
What are the official names of this protein?
RILP-like protein 2, Rab-interacting lysosomal protein-like 2, p40phox-binding protein.
What is the protein family that this protein belongs to?
Belongs to the RILPL family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium.
Protein: SECB2_POLNA
Sequence: MPDENKQPLFQIQRVYLKGLSLEQPNSPAIFLEEQSPTLEVAVSTIAEQQADGIFESTVTVSVTAKIRDKVAFLVEAKQSGIFEIRHLPAEQLNPALGIGCPTILYPYLRANIADAITRAGFPPVHLSEINFQAFYLQQQKNKMATQPGQTAEEPAMALEQE
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB 2.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_TRIV2
Sequence: MARLALLSVSNKTGLIDLARRLVEEFEFDLISSGGTAQALKDAGLPVTKVADYTGSPEILGGRVKTLHPRIHGGILARRDVPSDLTDLENNQIRPIDLVVVNLYPFEETIAKPGVTLAEAVEQIDIGGPAMLRASSKNFAHLTVLCDPAQYDEYLQELRQNNGVASLEFRQKAALKGFLHTASYDSAIASYLSGTQQHTLNGTELQSLRYGENPHQPAAWYQTGTTPTGWTAAKKLQGKELSYNNLVDLEAARRIIAEFTDTPAATIIKHTNPCGTALADTIVEAYQKAFNADATSAFGGIVALNRPIDAATASELTKTFLECVVAPDCDAEAQKILAKKSNVRVLTLADLSTGPKTLVKQIAGGFLVQAADDIAADTIQWQVVTERQPTADELAELLFAWKVCKHVKSNAIVVTSDRTTLGVGAGQMNRIGSTKIALEQAGDKAKGAILASDGFFPFDDTVRTAAAAGISAIVQPGGSLRDQDSVKAANELGLLMVLTGVRHFLH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: Y5677_BACAC
Sequence: MGNEFRVCDDCQATNVKTLIPKLKKVDSCATIEVGCQSYCGPGRKKSFAFVNNRPVAAPTEDELIVKIEAKLNK
What are the official names of this protein?
UPF0741 protein BAMEG_5677.
What is the protein family that this protein belongs to?
Belongs to the UPF0741 family.
Protein: YBEY_ACIBC
Sequence: MKISLSLQQDFQSPELELKRAQLKKIIETTLRHVGYKEDCEIGIACVDLEESHQLNLQYREKDKPTNVLSFPSDIPEEVLPMLDALPLGDLVICIPVVLQEALEQKKTAQNHFAHLLVHGVLHLLGYDHETSDEDAEEMEGLEIEILAKLNIANPYQE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_ROSDO
Sequence: MSWKTLDDMDVAGKRVLLRVDINVPVEEGQVTDRTRIDRIIPTLQDILAKGGTPIMLAHFGRPKGKVVPEMSLRVTLPALEAALGRKVTFIEEPNAERLSDLPEGIVVLLENTRFAVGEEANDPEMARFLATLGDVFCNDAFSAAHRAHASTTGVAHLLPSCAGRLMQAELSALEAALSTPQRPVGAVVGGAKVSTKIALLENLVARLDVLVIGGGMANTFLAAQGAKLGASLMEPDYMETARTIMQSAERAGCKLLLPVDGVVAREFKAGADFEVVALGKDTVLAEDQMVLDAGPQSVAAVMAAFRTLKTLIWNGPLGAFEITPFNQATNATALEAARLTKSGALISVAGGGDTVAALNQAGAAADFTYISTAGGAFLEWMEGKTLPGVAALQG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_BURP1
Sequence: MSERNAASARTVACLLGPTASGKTAAALALAARRPIEIVSVDSALVYRGMDIGTAKPTRDERAAVPHHLIDIVDPADAYSAAEFRADALRLVAQIAARGRTPLLAGGTMLYYRALTQGLNDLPAADPDVRATLDADAARDGWPALHARLAGIDPATAARLAPNDSQRIQRALEVYLLTGQPMSALLAAPPRDDDAAAGLRFVPVALEPSERAVLHARIAARFDAMLEAGFIDEVERLRRRDDLHLGLPSMRCVGYRQAWEYLDGCTDYRTMRDKGIFATRQLCKRQLTWLRAMPERIVVDCCAPDATVRAVDALERVLDGRAPA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: REBO_LENAE
Sequence: MSRGHKKITVLGAGVAGLVAAHELEELGHEVEVLEGSDRLGGRVHTHRFGEGGSVPFVELGAMRIPTKHRHTIDYIGKLGLTPKLKEFKTLFSDDGAYHTTSAGFVRVRDAAKVLVDEFRLLMSGRDLREETILFGAWLTAVGDAIAPADFRAALRTDFTADLLEVVDRIDLDPFLVGAARDQFDLHAFFAAHPEVRTSCTGKLNRFVDDILDETSPRLLRLEGGMDQLVDALVERIRGDIRTGHEVSAIDVREDHVAVTVHNGHGVNTLRSDHVLCTIPFSVLRNLRLTGLSTDKLEIIHDVKYWSATKVAFRCREPFWERDGINGGASFGGGRIRQTYYPPVEGDPTRGAVLLASYTMGDDADVLGGMPEAQRHEVVLDEVGRMHPELHEPGMVVEAVSRAWGEDRWSNGAGVTRWGKDVAACEEERDRAARPEGRLYFAGEHCSSTTAWIDGAVESALAAVRAIEAGDGR
What is the function of this protein?
Involved in the biosynthesis of the indolocarbazole antitumor agent rebeccamycin.  It generates the imine form of 7-chloroindole 3-pyruvate (7Cl-IPA) from 7-chloro-L-tryptophan (7Cl-Trp), with concomitant two-electron reduction of O(2) to H(2)O(2).  The enzyme is also active with L-tryptophan as substrate.
What are the official names of this protein?
Flavin-dependent L-tryptophan oxidase RebO, L-amino acid oxidase protein, L-AAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. RebO subfamily.
Protein: RS17_TOLAT
Sequence: MTDQIRTLQGRVVSDKMDKSITVAIERKVKHPMLGKIIVRTTKLHVHDENNECKTGDLVEIRECRPLSKTKCWTLVSVVEKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: QUEA_RUBXD
Sequence: MRTDELDYELPQELIAQRPAEPRDASRLMVVDVPSRGISHHVFRELPRFLGPGDVLVLNETKVIPARLFASRPGGGEVELLFLGERGGAWEALARPSRRLRPGMPLSAGEGERLEVVEELGEGRWLVRGRDVPGLLERAGRMPLPPYIEPTPEAEASYQTVYARTPGSAAAPTAGFHFTGRVLRGVEEAGARIARVVLHVGLGTFAPVREERLEDHRMHREYYAVPEETARAVEEAERVVAVGTTVVRTLESWARSGVREGESELFIYPGYEWRAVDALITNFHLPRSTLLALVMSFAGRELVREAYEVAVRERYRFYSFGDAMLLLGGGRSLR
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSG_PASMU
Sequence: MTETTTKKRWYVLQAFSGFEGRVATTLREYIKLHQMEDQFGEVLVPTEEVVENVAGKRRKSERKFFPGYVLVQMEMNDETWHLVRSVPRVMGFIGGTADKPAPISQREADRILNRLQESSEKPRHRKEFQPGEEVRVTEGPFADFNGTVEEVDYEKGRLKVSVSIFGRATPVELEFSQVEKTN
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: RLMKL_PSEA6
Sequence: MFEFLVTTSKGLDELLAQEITKLCPQLSVKTKPGQVLFTGEIEQAYKICLWSRLANRVMLKLADGHVDSADDVYQITSSVNWTSHFSVNSTFVVDFVGASHCINNSQFGALKIKDAVVDQFNELFESRPSVSKIEPDIRIQGRMWSDKLTVYLDLSGSSLHQRHYRTKTGLAPVKEHIACAMLVRSGWANDQQAPLVDPMCGAGTIAIEAALMAANIAPALKRERWGFTRWLQHDATLWQSLLDDANAQIITPNCVISASDIDHGVVSIAKENADAAGVFSGIKFNTIDACKVIPPKGHTKGYIVSNPPYGERLSEITALLPLFQAWGTSLKEHFKGWNLSLLTSNRDLLRSMKMFAHKEYKLMNGKLECQLVNFALDEKNCITRETSLSNNDFANRLNKNIKRLSKWLKSENTNCYRIYDADLPEYNVAIDRYGDWLVVQEYAAPKNVPEAKAKRRLHEVIVALPQVVDVPAEQIVMKVRAQQKGKSQYEKVSQKQKMLEVFENGAKFKLNLTDYLDTGLFLDHRVTRQLVQQRVKDKDVLNLFAYTGSVSVHAALGKAKSVTTVDMSNTYVDWAKENFALNKLKGPYEFIQADCLTWLERHNNQYDFIFIDPPSFSNSKRMDTTWDVQRDHVALLRNAVKCLRPGGEIMFSNNLRQFKLDEEGVSQLGLTIQDITQKTLPEDFKRNPKIHGCWVLTLNA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLD3_YEAST
Sequence: MTAAHPVAQLTAEAYPKVKRNPNFKVLDSEDLAYFRSILSNDEILNSQAPEELASFNQDWMKKYRGQSNLILLPNSTDKVSKIMKYCNDKKLAVVPQGGNTDLVGASVPVFDEIVLSLRNMNKVRDFDPVSGTFKCDAGVVMRDAHQFLHDHDHIFPLDLPSRNNCQVGGVVSTNAGGLNFLRYGSLHGNVLGLEVVLPNGEIISNINALRKDNTGYDLKQLFIGAEGTIGVVTGVSIVAAAKPKALNAVFFGIENFDTVQKLFVKAKSELSEILSAFEFMDRGSIECTIEYLKDLPFPLENQHNFYVLIETSGSNKRHDDEKLTAFLKDTTDSKLISEGMMAKDKADFDRLWTWRKSVPTACNSYGGMYKYDMSLQLKDLYSVSAAVTERLNAAGLIGDAPKPVVKSCGYGHVGDGNIHLNIAVREFTKQIEDLLEPFVYEYIASKKGSISAEHGIGFHKKGKLHYTRSDIEIRFMKDIKNHYDPNGILNPYKYI
What is the function of this protein?
Catalyzes the reversible oxidation of (R)-2-hydroxyglutarate to 2-oxoglutarate coupled to reduction of pyruvate to (R)-lactate.  Can also use oxaloacetate as electron acceptor instead of pyruvate producing (R)-malate.
What are the official names of this protein?
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3, D-2HG--pyruvate transhydrogenase DLD3, (R)-2-hydroxyglutarate--pyruvate transhydrogenase, D-lactate dehydrogenase [cytochrome] 3, D-lactate ferricytochrome C oxidoreductase, D-LCR.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
What are the subcellular locations of this protein?
Cytoplasm.