PharMolix/UniProtQA huggingface dataset:
Protein: COAD_BORBZ
Sequence: MRVAVFPGSFDPITWGHIDLIKRSLAIFDKVIVLVAKNKSKKYFLSDIERFSLTKDVISSLNFSNVLVDRYSGFIVDYALINSIKFIVRGIRAFNDFDIEFERYLVNNKLNFEIDTIFLPSSAEHLYVRSDFVKELMLKKDVDLSNFVPELVFNRLKSKFIDK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROPE_PLACH
Sequence: MIFNLKKSKKNEDGSNKDSKKTNETSGIEKKEKSNKWYNKIVNNSTKKDKDKNNDSIVYDDESKVGENDHHMKEYELEDQLKETLKSITALSIKVKEYEVKIEELEKELKLEKEKQINKEYEKELNEKSEFIKRQMELLKEKELNINLKENKINNKEIITLKREEKLNDIESEYIEKNKEKEKLNYEVTNIKMSLDKLTCEVQEKKDNLEKINKKVIEKENNLRELKEFMKEKNEIIESLDGTINDKKNAYEKLEISFEEKRKMIEMLDSKLIEKEENFANKQAKLEKENEIIIEKLKDIESREKDFKSKEEKFASMENELNTLKSDLSKNACQMEVYKLEIKDLSQSLVEKEREIFEIKNEYDDKINNMKEKLSSINDKGIDNTVLHSEEEKINKLLKEKETELNEIHKKYNLEIETIKNELNEKEEELEKNKKAHTVEVTNLTKEIKLLEKKTEDAKEGHKNELNELNNQLSKLNKEKDNIKNENTELNDKISSLNSEVNILNKDKQTLGNDIKTLNDLINNLKNEINTSDNKMNKMKEDLAMLNEEMEGKCVVIDEIEKKYKNEIFMLEEKLKEKENYADLNDEISILRNSIYVKEKEFIEMKEFYENKINLFNKNFEEKKNIYENELNSLRLKYDNEQGLIKQIDELNIQKLKTEEKYLQLYNDNMHMFRSICTKIDMPYSENIKGSDLVDFVTAYIKRRDESSSDANPDTTHKEMVAELEKRHAAIVAELEEKHKEEIAKLGEGHKEVVLRLGEQHKEETIILEEKHKDVVTKLGEQHKENIIKLEEEHKDVVTKLGDQYKEEIAKLKEEHAVVVAELEEKHKLGEGHKEMVDELEKRHADFVEGLEEKHKAETAKLEEGHKSEMNEVEKRHADFVEGLEEKHKAETAKLGEGHREVVAGLEEKHKEVVAELEEKHKEEIAKLEEGHKEVMAELGEKHKEVVAGLEAKHNLEEGHKEMVAELEKRHADLVAVLEEQHKAEIIKLGEEHKEVVAGIEEKYKVEAIKLAEEHKDVVTKLGEQHKEEIAKLEDGHKEVVNEVEKKNASLLNMLEENHKNEMIKLKEEHKESASDLVEKLYQKDEEVKNSNNKIEELTNVIKDLNDSIMCYKKQILEEVEKRNEYNEEINKLKIVQNEMKDMNDKKILEKENEIKKLNKKLSNYKVFETKENTYKNSEMVVNENKERIIVDSVCKENISESDVEGKGGNLKMTLSLKKKERNIFSINDNKNESSELVDTIKSAYINKIEMYKKEIEDNGKNIEDLKNKILDLSNELINLENMKNVLTDENNNLKKEIEIKDNKLNEKEKNENTEILNLNDDIIKLKKEISEWKDEEEKLTKENIKLKNDIEQINKEYKIKEENLMIKFNENINEVTSLKNQIEIEKMKLEELNKNYELLLAEKRETNMSISNDDNKIVENNILEDTDSKQNNLNKNVEDKTGDDINCEKNNDQAKEISYLKDEIKKISMLYGEELNRKNSYDEKVKNLTNELKELKIRNKKGEEAIAELNKLKNIKEKNKSVKQNDESSSNNIITKDGDKTPEYVSNDDKIQKDWKANLVLKLKEKPDLWDNINSLEKENFRVMSIVKENKNVQNDKIVGIYSYFKKCEKELKNDMLVICLVLKDILSILFLNDNFVNLFEKIDKILWKQMYIPTEIRILFLRYFSFLDKLRNYVKCVNEEYVNNERYEYSWALFQTYLETASNLKKEMIYYVLEKAEKDSCENNSSNFDKPKITDILNFSKDSIRLKTIAQLRKELNFEREAKNILNYDYQIILNKYHECLRKLKIVKNMARELDFNYNVSSKFSIKKELEMCSDENDEFKYNNIKNNEEKNDTIKDPKHNNLIQKIINLQRNKKTEKKKNNLVNEINTMYPGDTTPKGKIFTTNDNSKQNEILKKKDNINNNITHKNVYTGQVKNIFNEPVERKVRISFIHKSPFN
What are the official names of this protein?
Repetitive organellar protein.
What are the subcellular locations of this protein?
Host cell membrane. Note=Localizes to a punctate structure in the cytoplasm which could correspond the rhoptry or another apical organelle (PubMed:9747969). Localizes to the cell surface of the host erythrocytes (By similarity).
Protein: YBLJ_SCHPO
Sequence: MFLRPWSRNFLCSCRGFSVCTPYASIKSASELALKNISELQALQKIQNHTEKLKFFSSKLHNKGEPFTLQLGDLITEHTSVPELNEILDKFSQSNELFTMRFLEKASIIAHKNRSAELARRLRTYAANAMIDLSRVAFVNIFWTLLKTRDKEGIVETIEGQPIAFKVARRIFRRLLVYTSEAGENIEICFFLTNSLFKRLLNNREALSKDEKSELQNLYYDLLLCFSYSYYVPGVKLLLPMLYNGSFKEINRTAIDRSLLALLSTGELEAALELLVYLKNNNIPINDAYLRMMVINFCLANKPTLAVRFCQAWFKQSKMLSSTENLLLIAESLSRASNDFAAISKQMQPFSIESSSFYLPSHRLLMLVALMMKNSSGILHSYAVLKKANAITNKELRIMMQHAMDLRSTEFAEAVLKESEFTLQSNRSQLLMDFVAILFLNKEYTKAFATLEKTFASKIKPSHNIISFSLSLVKRFGTKNDLFFLRRSFKNMGIETLDEIEKNLPPKVVYRCFNY
What are the official names of this protein?
Uncharacterized protein C106.19.
Protein: PHNC_PSEPK
Sequence: MTASNAAIHLYGASLRHGQVRALDAVSLRIAQGERVAIIGPSGAGKSSLLHLMATAIQPSSGRLELLGEQPWALSARARQRLRARVGLVHQSPPLPPRQRVVTAVLAGRLGQWGTLRGLLNLLYPSDVPGARQVLAELGLADKLFVQCGQLSGGQLQRVGIARALYQRPQVLLTDEPVSAMDPVLADHSLALLNRHAQATGVTLVASLHAVELALAHFPRVIGIREGQVVFDCPAEAVTEQLLDALYANEQLAPPPTQGPTLTVQIPRC
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y088_UREPA
Sequence: MDFQKLAQELKKMQNTLSKKQKEFEEKVFDFDYKGYVLVKIKGDLNIEAIEIKTEIVDPEDKETLQDILRAAINEAISITCKERDAIMNATIPKGTGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein UU088.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GLGX_SALTI
Sequence: MTQLAIGEATPHGATYDGHGVNFTLFSAHAERVELCVFDSRGNERRYDLPGRRGDVWHGYLAGARPGLRYGYRVHGPWQPAQGHRFNPAKLLLDPYARQVEGELKDHPLLHGGHDEPDYRDNAAVAPKSVVISDHYDWEDDAAPRTPWGKTVIYEAHVKGLTYLHPELPQEIRGTYKALGHPVMVAYFKQLGITALELLPVAQFASEPRLQRMGLTNYWGYNPMAMFALHPAWASSPETALDEFRDAVKALHRAGIEVILDIVLNHSAELDLDGPTFSLRGIDNRSYYWIRDDGDYHNWTGCGNTLNLSHPGVVEYACECLRYWMETCHVDGFRFDLASVMGRTPTFRQDAPLFAAIKACPVLSTVKLIAEPWDIGEGGYQVGNFPPPFAEWNDHFRDAARRFWLPRNLTTGEFACRFAASSDVFKRNGRAPGASVNLLTAHDGFTLRDCVCFNQKHNEANGEENRDGTNSNYSDNHGKEGLGGPLDLMERRRDSIHALLATLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNALTWLDWQQANRGLTTFTAALIRLRQQIPALTGNSWWEEGDGNVRWLNKNAQPLSADEWQNGPKLMQILLSDRFLIAINATLEVTDIVLPEGEWRAVPPFAGEDNPVITAVWQGLCVFQRG
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: ERF1_HUMAN
Sequence: MADDPSAADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (PubMed:7990965, PubMed:24486019).  Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes (PubMed:30682371).
What are the official names of this protein?
Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, eRF1, Protein Cl1, TB3-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
Protein: MIP_LEGPC
Sequence: MKMKLVTAAVMGLAMSTAMAATDATSLATDKDKLSYSIGADLGKNFKNQGIDVNPEAMAKGMQDAMSGAQLALTEQQMKDVLNKFQKDLMAKRTAEFNKKADENKVKGEAFLTENKNKPGVVVLPSGLQYKVINAGNGVKPGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQVSQVIPGWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGPIGPNETLIFKIHLISVKKSS
What is the function of this protein?
Essential virulence factor associated with macrophage infectivity.  Exhibits PPIase activity.
What are the official names of this protein?
Outer membrane protein MIP, Macrophage infectivity potentiator, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: FCL_ECOLI
Sequence: MSKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFRG
What is the function of this protein?
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
What are the official names of this protein?
GDP-L-fucose synthase, GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_SYNSC
Sequence: MAQPRIGQKVVVDVPATTANLGPGFDCLGAALDLNNRFAMRRIEGGGERFELIIEGSEGSHLRGGPENLVYRAAQRVWKAAGLEPVALEARVRLAVPPARGLGSSATAIVAGLMGANALVGEPLSKEKLLELAIDIEGHPDNVVPSLLGGLCMTAKAASQRWRVVRCEWTPSVKAVVAIPSIRLSTSEARRAMPKAIPVSDAVVNLGALTLLLQGLRTGNGDLISDGMHDRLHEPYRWRLIKGGDQVKQAAMEAGAWGCAISGAGPSVLALCEEDKGPAVSRAMVKAWEAAGVASRAPVLNLQTSGSHWQPAEDE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_THIEL
Sequence: MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGEIEGTCITRAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRDASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPIDFCIDLQIKRDRGYQTELRKNYQDGSYPIDAVSMPVRNVNYSIFSCGNGNEKHEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHAEEEGTSFEENKNRFTPPPFTFKKRLTNLKKNKKGIPLNCIFIDQLELTSRTYNCLKRANIHTLLDLLSKTEEDLLRIDSFRMEDRKHIWDTLEKHLPIDLLKNKLSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PURA_CAEBR
Sequence: MTSAARKVSVLLGAQWGDEGKGKIIDFLIENHKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSELAHNGVLSEPGWEKRIMISSEAHLVFGVHSQVDGRQEDSLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMADFEEFSEKYRRLVEHYKKQFPSIEVDVDGELARFKEHREKLAELKLVGDTVGFIHEQRTNGKQVLIEGANGALLDIDFGTYPYVTSSNSTVGGACTGLGVPPTAIGSVIGVVKAYQTRVGTGPFPTELFDADGEKLQSIGKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTDIALTKLDILDTFPTIKVAVGYKLNGQTLTAPPAQTNAWGAVEVEYKEFEGWMEPTVGVRKYEDLPEKCRQYIQFIEEFIKVPIVYIGVGAERESLIVRQKQ
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_DROSE
Sequence: MSLQSIKYSRGSLEILDQLLLPGQSKYVVVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVEINPEDFENKKSLRQEIEGKLNYLVSARPTAVNMKIAADELITLANELYKDEAIDVTQMKHRFLDATEAMLKKDIADNRAIGANGAQAILQRVAKAGKTTAGTTGSVRVLTHCNTGSLATAGYGTALGVVRQLAELGKLEHVYCTETRPYNQGARLTAYELVHEKFPATLVLDSMVAALLRAKNVAAVVVGADRVASNGDTANKIGTYQIAVVAKHHDVPFYVAAPLTSIDLAIPGGDHIIIEERPDREMTHVGEHRIAAPGINCWNPAFDVTPASLITGIITERGVFKPAELKEAITKLLES
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPE_ALKCK
Sequence: MATIQVSVITPDGAVYEGDAELVVVKTVEGELGIKAKHIPLVSPLAVGPARFIKEGKEEQVAVSSGFVEVRPDHVSILAEAAERPEQIDTERARKAKERAEQRLASEHVDRKRAEAALQRAITRMDVAKHKGA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GLYA_THEPX
Sequence: MDIEIIRKTDPEIADAIEKELIRQRNKIELIASENFVSRAVMEAMGSPLTNKYAEGYPNKRYYGGCEYVDIAEELARERLKKLFGAEHANVQPHSGAQANMAAYFALIKPGDTVLGMDLAHGGHLTHGSKVNFSGQIYNFVSYGVREDTGYIDYDEVERVAKKHKPKLIVAGASAYPRIIDFKRFREIADKVGAYLMVDMAHIAGLVAAGLHPNPVPYADVVTTTTHKTLRGPRGGAILCKEEYAKAIDKALFPGTQGGPLMHIIAAKAVCFKEALTDEFKEYQKRIVENAKALANALMERGINLVSGGTDNHLMLLDLRNTGITGKELETRLDEVNITCNKNAIPFDPLGPNVTSGVRLGTPAVTTRGMKPEDMVEIADIIVNVIRDENYKEKAKERVANLLKKYPLYEDLI
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCH1_YEAST
Sequence: MKTQYSLIRKIWAHSVTEFLKSQWFFICLAILIVIARFAPNFARDGGLIKGQYSIGYGCVAWIFLQSGLGMKSRSLMANMLNWRAHATILVLSFLITSSIVYGFCCAVKAANDPKIDDWVLIGLILTATCPTTVASNVIMTTNAGGNSLLCVCEVFIGNLLGAFITPALVQMFTNRAPFAYGNPATGNGIGALYGRVMKQVGLSVFVPLFVGQVIQNCFPKGTAYYLGFLKKYHIKIGSYMLLLIMFSSFSTAFYQDAFTSVSHVCIIFLCFFNLGIYIFFTGLSYLCARPWFILKLFPHEPIEGKSTRLYRYSYNIFRPFYYSKEDAICIMFCGPAKTAALGVSLITSQYGDKKEHLGKLLVPLVLYQVEQVMTANFFVSLFKRWIQKDAQADGSESSCANENEEVDLEKIISIGTGENQSVLSNNVPYTQPR
What is the function of this protein?
Solute carrier protein that negatively regulates the cytosolic calcium homeostasis in response to high levels of extracellular calcium.
What are the official names of this protein?
Solute carrier RCH1, Regulator of calcium homeostasis 1.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bud neck. Note=Distributes as multiple foci in the plasma membrane prior to cell division, moves toward and concentrates at the bud neck as the bud grows in size, and disperses again along the plasma membrane immediately prior to cytokinesis.
Protein: CML14_ARATH
Sequence: MSKDGLSNDQVSSMKEAFMLFDTDGDGKIAPSELGILMRSLGGNPTESQLKSIITTENLSSPFDFNRFLDLMAKHLKTEPFDRQLRDAFKVLDKEGTGFVAVADLRHILTSIGEKLQPSEFDEWIKEVDVGSDGKIRYEDFIARMVAK
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML14, Calmodulin-like protein 14.
Protein: FAM50_ANOGA
Sequence: MAYYKGAASEGGRAAQLMKRRELAQQEVEFRKKKIEEDLKVSNIENKFAAHYDAVEQQLKSSTIGLVTLDEMKAKQEDIVREREKKLAQKKEEKDKEKLKALEAKLAEKDRQKRQIQALSFDPDDEPDGDDANDGDEGSGKESEKEDVKEELTVVKRSWKEQVPSGVKKIRKNPDVDTSFLPDREREERDNRLREELRQEWAMKQATLKDQEITITFSYWDGSGHRKSVAMKKGNSIYQFLQKCLEMLRKDFSELKTVMADQLMYVKEDLILPHHYTFYDFIVTKARGKSGPLFNFDVYDDIRMISDASVEKEDSHAGKVLLRSWYERNKHIFPASRWEPYDPTKVYDKYTIKDKSKK
What are the official names of this protein?
Protein FAM50 homolog.
What is the protein family that this protein belongs to?
Belongs to the FAM50 family.
Protein: KRT83_BOVIN
Sequence: MTCGFSTVGSGFGSRAFSCVSACGPRPGRCCITAAPYRGISCYRGLTGGFGSRSVCGGFRAGYCSRSFGYRSGGVGGLSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKCLNNRFAAFIDKVRFLEQQNKLLETKLQFYQNRQCCESNLEPLFEGYIETLRREAECVEADSGRLSSELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYIRKSDLEANSEALIQEIDFLRRLYEEEIRVLQANISDTSVIVKMDNSRGLNMDNIVAEIKAQYDDIASRSRAEAESWYRSKCEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEVENAKCQNSKLEAAVTQAEQQGEVALNDARCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCSGNLAVSTGLCAPCGQLNTTCGGGSCSLGRC
What are the official names of this protein?
Keratin, type II cuticular Hb3, Keratin-83, K83, Type II hair keratin Hb3, Type-II keratin Kb23.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: MET3_GIBZE
Sequence: MANTPHGGVLKDLFARDLPRQSELEAEAQKLPALTLSERHLCDLELILNGGFSPLEGFLTEKDYNGVVENNRLADGALFSMPINLDVNQAEIDQLGLKAGARVTLRDFRDDRNLAILTVEDIYRPDKVNEAKKVFGSDDDTHPGVKYLFDTAKEFYVGGKLEAINRLEHYDFLDLRFTPSELRAHFNKLGWQKVVAFQTRNPMHRAHRELTVRAARSQQANVLIQPVVGLTKPGDIDHFTRVRVYKALLPRYPNGMAALALLPLAMRMGGPREALWHAIIRKNHGATHFIVGRDHAGPGKNKQGKDHYGPYDAQVLVQEHQEELGIKMVEFQAMIYLPDSDEYLPINEIPEGTRTLNISGTELRHRLRTGKDIPEWFSYPEVVKVLREENPLPAEKGFTVFMTGYQNSGKDQIARALQATLNQGGGRPVSMLLGENVRHELSPELGFTRKDRDLNIQRIAFVASELTKAGAAVIAAPIAPFEDARKAARDLVEKSGPFFLVHVATPLEYCEKTDRKGVYAAARNGEIKNFTGVDDPYEAPAKPDLVVDLEKQNVRSIVHQIVLLLESNGLLDRL
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOC_BACFR
Sequence: MKLKRLYPPQKSVNSLHSETGTRCEVAGCPPLRKEALLFFAGWGMDETPFMHNLPPNKDLIICYDYRSLDFDSTLLSTYEGIYVVAWSMGVWAASQVLPDSNLPLKQSIAINGTPFPIDDMRGIPPAIFEGTLNNLNEATLQKFRRRMCGSGSAFQAFLEIAPQRPVEELKEELAAIGRQYSELPLSTFVWNKAIIGESDHIFPPKNQEQAWQKYCNEIQRYDGAHYDEKILKENLAPAAASSKLLIAQRFTKAIGTYPHEARVQQQIARKMCSLLQQHLPAHSLRRVVEFGCGTGTYSRLLLRSFRPEHLLLNDLCEEMRHSCRDILNERVSFLPGDAEALDFPHGTELITSCSVLQWFEHPDAFFRKCENILNAQGYIAFSTFGKENMKEIRQLTGQGLAYRSREELTASLSALYDIVHTEEEVISLNFNNPMEVLYHLKQTGVTGTCNQSWTRSKLNLFCQEYERLFSPGKGSVSLTYHPIYIIAKKR
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity).
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: DAPB_POLNS
Sequence: MKIAIAGTIGRMGKMLIEAVLNTADAQLVGALEHTSCPQLGEDAGAFLGKKTGVLISSDVAQVLANAQFLIDFTRPEGTMAHLAIAEKTGTKMIIGTTGLSADQIAGLKKVSANLAIVFAPNMSVGVNATFKLLEIAAKMLSQGYDIEIIEAHHKHKVDAPSGTALKMGEVIAEALGEKLDDVAVYAREGHTGERKEGSIGFAIIRGGDIVGDHTVLFAGDGERIEISHKSSSRQSYAQGSLRAARFLQNQKNGLFDMQDVLGLRK
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBA_ECO55
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: AROK_MYCLE
Sequence: MAPKAVLVGLPGAGKSTIGRRLSKALGVSLLDTDAAIEKQTGRSIADIFAIDGEEEFRRIEEGVVRAALVEHDGVVSLGGGAVTSPGVCAALAGHIVIYLEINAEEAMRRACGSTVRPLLAGPDRAEKFQDLMARRVPLYRRVATIRVDTNCHNLGAVVRYIMARLQAQLATPVSGGDRKSSEAERSGAPLRKSSEVVK
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECH20_RHOJR
Sequence: MGITSTTDGDGITTVTVDYPPVNAIPSRGWFELADAVLDAGRNPDTHVVILRAEGRGFNAGVDIKEMQATDGYGALVDANRGCAAAFAAVYDCAVPVVVAVNGFCVGGGIGLVGNADVIVASDDAVFGLPEVDRGALGAATHLARLVPQHMMRTLYYTAQNVTAQQLQHFGSVYEVVPREKLDDTARDIAAKIAAKDTRVIRCAKEAINGIDPVDVKTSYRLEQGYTFELNLAGVSDEHRDEFVETGKPRSHSNNRKG
What is the function of this protein?
Involved in the final steps of cholesterol and steroid degradation (PubMed:28377529).  Catalyzes the hydrolytic ring D opening of (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA (HIEC-CoA) to (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA (COCHEA-CoA) (PubMed:28377529).
What are the official names of this protein?
(7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA hydrolase, HIEC-CoA hydrolase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: DNLJ_MYCPN
Sequence: MAKVAQIRAIVEQLKRYDYHYYVLDDPLVSDFEYDQLYKQLQALEQAHPELIQPDSPTQRVGGIVVEAFNKFPHQNPMLSLDNAFDTATIASFIANINNLTGVQNRFVVEPKIDGVSISLTYENGLLTRALTRGDGLVGEDVLSNVKTIKSIPLTIPFHKQVEIRGEIFVDKKTFAQINENLAKPFANARNLAAGTLRNLNSEVSAKRKLKAFFYFVPNALTLGCRSQSAVLAQLKQWNFPVSKAVASFDRPEALIEYLEQFDQTRDQLNFQVDGLVVKLDNFHFYDQLGFTSKFPRWALAYKFKPKFVQTKLRGVLVTVGRTGKINYTAQLDPVNLEGTVVSAATLHNFDYIKEKDIRLNDTVIIYKAGEIIPKVLEVCLPLRTAANQPIPEQTHCPACQAPLVQYKDEVDQYCTNERCDQRNLEAINYFVSKTAMDIQGLSIQTISKLYENNLVRSVVDLYHLKEHKAAVLALELKIGEVLFNKLISSIEQSKTKGMARLLTGLGIKHVGQVLAKSLTKHFENIDALQSASMETLLELPDVGPTVAESLFNWFHNDNNLQLLAALKAVGVQMDALKSNTNFDTASIYFQKSFVITGSFPISRDTIKNLLVNKYDCRFTNNVTSKVDFVLAGIKATPRKLEQAKALNIPIINEPIWT
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PSBH_CYAP4
Sequence: MAKRTWLGDVLKPLNSEYGKVAPGWGTAPLMAVFMGLFLVFLLIILELYNSTLMLEGVNVNWTALGS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.