PharMolix/UniProtQA huggingface dataset:
Protein: CH604_PARXL
Sequence: MAAKEIIFSDVARSRLVEGVNILANAVKVTLGPKGRNVVLERSFGSPVVTKDGVSVAKEIELSDRVQNIGAQLVKEVASRTSDAAGDGTTTATVLAQAIVREGQKYVAAGLNPLDLKRGIDKAVIAAIEELKKISKPTTTSKEIAQVATISANGEESIGQRIAEAIDRVGKEGVITVEDGKSLDDELDVVEGLQFDRGYLSPYFINDQDKQVAVLDNPFVLLHDRKVSNIRDLLPILEQVAKAGRPLLIIAEDVEGEALATLVVNNIRGILKTVAVKAPGFGDRRKALLEDIAILTGGQVIAEETGLSLEKATLAELGQAKRIEVGKENTTVIDGAGDSKNIEARVKQIRTQIEEATSDYDREKLQERVAKLAGGVAVIKVGGATEIEVKEKKDRVDDALHATRAAVEEGIVPGGGVALIRVKQAISGLKGANADQDAGIKIVLRALEEPLRQIVTNAGEEASVVVAKVAQGTGNFGYNAQTGEYGDLVQSGVLDPTKVTRTALQNASSVAGLLLTTDATVHEAPKDTPAAGQPGGPGAGGPGLDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 4, 60 kDa chaperonin 4, Chaperonin-60 4, Cpn60 4.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB2_NITMU
Sequence: MDAAAPDLGIGIVAAVRGGIVDIRFANRPPSIRSLVRTGKAGEIVIEILSQLDAHRVRGIALTPTQGLARGMLVKDTGGPLRAPVGRATLSRMFDVFGEVIDRKPPPCDAQWRTVHHSPPPLVRRSTRSEIFETGIKIIDVLMPLERGGKAGLLGGAGVGKTILLTEMIHNVAGRHRGVSIFCGIGERCREGEELYRDIMAAGVLENMVMVFGQMNEPPGARFRVAHAALTMAEYFRDDEHRDVLLLVDNIYRFIQAGMEVSGLMGQMPSRMGYQPTMGTELAQLEERIAHTDNGAITSIQAVYVPADDFSDPAAVHAFSHFSASIVLSRKRASEGLYPAIDPLQSGAKMATPSVIGERHYRIAQETRHTLAQYTELKDVIAMLGLEQLSPEDRALVARARRLERFFTQPFFTTEHFTGIKGKLVSLEDALDGCERILRDEYRDLPEQALYMIGKASEAEPGGSAKNASS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DYRK2_HUMAN
Sequence: MLTRKPSAAAPAAYPTGRGGDSAVRQLQASPGLGAGATRSGVGTGPPSPIALPPLRASNAAAAAHTIGGSKHTMNDHLHVGSHAHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLPVVPERQLDSIHRRQGSSTSLKSMEGMGKVKATPMTPEQAMKQYMQKLTAFEHHEIFSYPEIYFLGLNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTSVKRITESTGAITSISKLPPPSSSASKLRTNLAQMTDANGNIQQRTVLPKLVS
What is the function of this protein?
Serine/threonine-protein kinase involved in the regulation of the mitotic cell cycle, cell proliferation, apoptosis, organization of the cytoskeleton and neurite outgrowth.  Functions in part via its role in ubiquitin-dependent proteasomal protein degradation.  Functions downstream of ATM and phosphorylates p53/TP53 at 'Ser-46', and thereby contributes to the induction of apoptosis in response to DNA damage.  Phosphorylates NFATC1, and thereby inhibits its accumulation in the nucleus and its transcription factor activity.  Phosphorylates EIF2B5 at 'Ser-544', enabling its subsequent phosphorylation and inhibition by GSK3B.  Likewise, phosphorylation of NFATC1, CRMP2/DPYSL2 and CRMP4/DPYSL3 promotes their subsequent phosphorylation by GSK3B.  May play a general role in the priming of GSK3 substrates.  Inactivates GYS1 by phosphorylation at 'Ser-641', and potentially also a second phosphorylation site, thus regulating glycogen synthesis.  Mediates EDVP E3 ligase complex formation and is required for the phosphorylation and subsequent degradation of KATNA1.  Phosphorylates TERT at 'Ser-457', promoting TERT ubiquitination by the EDVP complex.  Phosphorylates SIAH2, and thereby increases its ubiquitin ligase activity.  Promotes the proteasomal degradation of MYC and JUN, and thereby regulates progress through the mitotic cell cycle and cell proliferation.  Promotes proteasomal degradation of GLI2 and GLI3, and thereby plays a role in smoothened and sonic hedgehog signaling.  Plays a role in cytoskeleton organization and neurite outgrowth via its phosphorylation of DCX and DPYSL2.  Phosphorylates CRMP2/DPYSL2, CRMP4/DPYSL3, DCX, EIF2B5, EIF4EBP1, GLI2, GLI3, GYS1, JUN, MDM2, MYC, NFATC1, p53/TP53, TAU/MAPT and KATNA1.  Can phosphorylate histone H1, histone H3 and histone H2B (in vitro).  Can phosphorylate CARHSP1 (in vitro).
What are the official names of this protein?
Dual specificity tyrosine-phosphorylation-regulated kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates into the nucleus following DNA damage.
Protein: SCX2_ISOMC
Sequence: KDGYPMVRAGREKGCKIWCVINNESCDSECKIRKGKKGYCYFWKLACYCEGLPANEQVWTYEKNTCKP
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  Is toxic to both insect and mammals.  Induces paralysis in Acheta domestica crickets, but does not induce death, whereas intracerebroventricular injection into mice causes immediate death (at a dose of 0. 05 ug/g).
What are the official names of this protein?
Beta-toxin Im-2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LSB6_SCHPO
Sequence: MESTFHSDTLDSFPNYQENSLNTNEEQTNPLESLRDGWASSNSSSSSSLLLPDENEGNEVFGSLKGLVTQSKFGQWANKLSKSLQARRRKSESISKPRVYYSVFMAPSWVLHAEKHWEEYPHYAGYDYKDYVRLLDATKEAIAHGVFPVLISKGSSGSYFVKNKVQKNIAVFKPKDEEPYGKLNPKWTKWFHRNLFPCFFGRSCLIPNTSYLSEAAACVLDRGLGLYLVPYTSVASISSPTFNYDYFARKAFLTRNKPLPEKTGSFQQFLDGFVVASKFFAQHPWPGTRHRETREYTESVASSEDFDIFDPFLAENEIETEFWTEELRLKFRFEFEKLVLLDYLMRNTDRNLDNWMIKICYEPCDNEEYYKSINLLSTNLTPNMSANSVDPAISQTSDFWKGPHFQIGAIDNSLAFPYKHPDSWRSFPYGWLSLPRSLFTQPFTEFTRQLFLHKLTSREWWEKLSDDLRNVFNQDLDFDEKMFSRQLSLVKGQAYNIVEVLKNPLMNIYDLLELPNLYVVEDVVRIEVNEPTSANSEEAEFGLPIKRDYGSILHPSCSQTFPPYPGSQLLQATPGRSFSSNAEALLPLNYITLLSKDSSSPKMLKDVIFERLQCASSNAVFSTC
What is the function of this protein?
May play a role in endocytic and/or exocytic pathways.
What are the official names of this protein?
Phosphatidylinositol 4-kinase lsb6, PI4-kinase, PtdIns-4-kinase.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Protein: P2C63_ORYSJ
Sequence: MASSQQAVRETGRGRASSSSAGGRKVTFGYHLVEGKTPHGMEDLHVAEFRRLDDGNEDGGDGGSTAVTAILINGETLAVANVGDSRAVAFDVRAGRAQQLSVDHEPLRERDAIEHCGGFVTEIHGDVPRVDAQLATSRAFGDRQIKEHISSDPNVTIEDVGGRRRRWWHGARRPRQRRGVEECFLQRLAEYAICIHGASMEHRNFHVHSSHVHYFEIPPFKEV
What are the official names of this protein?
Putative protein phosphatase 2C 63, OsPP2C63.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: PURL_SACS2
Sequence: MGINLLPIEMDEIRKRLGREPNETEWRVIDAVWSEHCSYKSSKIFLKSFSIDSPNVIMGIKDWQDAGAVDIGDGWAVVIKVESHNHPSAIDPFNGAATGVGGIIRDIISKGAKPIALMDMIRVGNLKIKKNVWLLKNIIAGIAAYGNSIGVPVVGGELSFDDTYNDNPLVDVAAIGIVRKDKIKPSIVDKAGLKLVLAGLTGVDGLGGASFASRKLSGEDEIGAVQIADPFAGKIILDVTLEIADKVEAIKDLGGGGLAVAVTEITNGLGATVDIEKIPLRVKNMNPSDVIISETQERMLYAVEEKNVKEVCEAFEEYEYPCSVIGEITNEPVIKFRYIGKDLVSLPTNVLLNPPRFLWPIKNTKKNVEEKIVDLPLESAIYTVLTHPDLVSKGWAYSQFDYEVNTSTVVKPGDADSAVVSLPNGKLLAIKADANPDMCAEDGYECGKGIVAEAYRNLATVGARGMVAVDHLQFGDPKKAEVYYTFVEAIRGIGEATRFFNIPIVGGKVSFYNENNQGRPIKPTPLIVMAGLVQDKLLKNRVEDNLYVVSVGYTRKELGGSLLSKIFKIPSQAPKVRLQEDLLSSEVVIDSINEGKITFAKDVSRGGLAASLFSILVHGYGVEISTKSILSDTDNVIENLFSESSGRFIVLTNEPEWIVEKSKSKGIVASIIGRVNKKTNILTIDNIDYNLKNIVDNYFNFLEEVMGNG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKT45_CYRHA
Sequence: MGTARFLRAVLLLSVLLMVTFPALLSAEHHDGRVDICRLPSDSGDCLRFFEMWCFDGTTCTKFVYGGYGGNDNRFPTEKACMKRCAKA
What is the function of this protein?
Dual-function toxin that inhibits both serine proteases and voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type U15-theraphotoxin-Hhn1k, U15-TRTX-theraphotoxin-Hhn1k, Kunitz-type serine protease inhibitor HNTX-45.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 03 (sub-Kunitz) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLK_STAXY
Sequence: MNKIILAADIGGTTCKLGIFDENLNRLSKWSIDTDTSDTTGYLLLKNIYDSFIQHIDKSDNTFSDVLGIGIGVPGPVNFETGEVNGAVNLYWKGTVNVRDIFKQFVDCPVYVDNDANVAALGEKHKGAGNGADDVVAITLGTGLGGGIISNGEIVHGHNGSGAEIGHFRVDHDQRFKCNCGKSGCIETVASATGVVNLVNFYYPKLTFKSSILQLIKDNKVSAKAVFDAAKAGDQFCIFITERVANYIAYLCSIVSVTSNPKYIVLGGGMSTAGLILIENIKTEYHNLTFTPAQQNTEIVQAQLGNDAGITGAAGLIYTYIIEKDGVK
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCPE_SCHPO
Sequence: MKLILLAYFAVLSNILSSVEGRVRYSKRPNHKLGTAEYAECMSNAPIVFNRFDASYYTRNLSVVFNILGYSSVDANVTFDIIVEAYGEQRARFTFDPCEINLNTVCPVARDTAITTQGILPVSPQDVQMIPKIAWGIPDFEGLVRFRMYRSEDIAASSIDNSTPLACMIATLNNGHTFKNKVVKALSGTALALSIAGVLGFYVIGMEHSTYLTRQVFINSVPSLQHMGELLQCIAFTGAIGITQPKVLVAWASNFAWILGFITNKEIENSLESFRKHSNGNLSSPKIGGVHRRDAVATNPQSPIPGFYHGFQGLATEVGTLTTNLFTLTLIWFLISLAIAGGIVIIFVLIIKFLRQTRIIAKSSCDYITRYWFRVLFNACMRWVLVCWPVLVTMIIYQFTLREAYGPVILAALLLALLFGLFLWLTIKVIRVITTSGLSNEDNPETLISDPKIYTWWGWLYLDLKERRWLYVYACFAHYFSFALVLALVQQFAKIQTILLFVIEIISFILLAVFRPFVGFKNSFCVFLVALTRVVSFALLIPIAFDLAIIPKVIIAIILIIIQGLVFSFMALWSLWNFITMLGTAWPAISYTVPWLRRLIDEYQRQLHIDFENPAVSASEKLSTEEIIPQESNFEEPSTTKKEGNVDTKEDGNDDVFSLVNASPMRPASTIPSHSCDNGINEMQRTV
What are the official names of this protein?
Uncharacterized membrane protein C663.14c.
What is the protein family that this protein belongs to?
Belongs to the transient receptor potential (TRP) ion channel family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RLMN_HISS2
Sequence: MSDKINLMNLTRQQMRAFFQELGEKPFRADQLVKWIYHFGEDNFDHMTNINKKLREKLKTVAEIKAPEIAVEQRSADGTIKWAMQVGDQQVETVYIPETDRATLCVSSQVGCALACTFCSTAQQGFNRNLTVSEIIGQVWRASKIIGNFGVTGVRPITNVVMMGMGEPLLNVANVVPAMEIMLDDFAYGLSKRRVTLSTSGVVPALDKLSEMIDVALAISLHAPNDELRNEIVPINKKYNIKMLMESVNRYLNVSNANHGKVTIEYVMLDHINDGTEHAHQLAEVLKNTPCKINLIPWNPFPDAPYAKSSNTRIDRFQKTLMEYGFTVILRKTRGDDIDAACGQLAGDVIDRTKRTAQKKRFGKEIGTHQIY
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBY_PARMW
Sequence: MLGIDARLFLVVAPILAAVSWAAFNIGRAAVGQLQLLIKRSRA
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: UPPP2_CHRVO
Sequence: MNAIEALLFAVIQGVSELFPVSSLGHGVLIPDWLHWSINRTHPDFLPFMVMLHLGTAAALLIYFRRDWVDLIGGWLKAGGRASNPHARLMWLVIAGTLPAGLLGLLLEKQLRALFASTTAVLVFLALNGLLLLWGDKLKKKTASHELSELSFAGAIKIGAGQALALLPGFSRSGATLVAGLAHGLDYASSARFSFLLATPIITAAGLLEIPKLAHRGNGSAEWGLLLACGAVSGLCAYASTWFLMRYFKKTEIESLRPFGFYCLLVGVVGLLFKLV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 2, Bacitracin resistance protein 2, Undecaprenyl pyrophosphate phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BUR2_KLULA
Sequence: MVLSASEEIANSQPSGNGKTSLDIKQNEGNPQFNPRNLWPDIIKCPKNEWTFEYTDIIKRLGTDEEKIQLTKKRMEKCLMYFHKLRKEMKLFDHTYTAACILFYRYWYKYDLPPTIPQCIHLAQAILVTACKTMENNRPTDHYIKATCDFMMKDGPSPTGQKLNVEKLKWEVRDQLVSYEKKVLCQLGFDLDIDNPKELIEEIFSGYYRHVRDTDIDASLREIFPVILQEARNFIIQTGTQPISLLCDGYTLVALALIFAGVTFQKNKEPGFSFPHNFFRRRFPVIITSEIIASLFSHYQQLEKAFFDLKSNKNSALSITVDEIDKVIDEDRQLDPEPFNPYDYDIIKEGEVNEELLNYTERKIEELSNRIMSERSIKRPSEPPAEQATKKPRF
What is the function of this protein?
Component of the BUR kinase complex involved in transcription regulation.  This complex phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes.  Also required for histone H3 methylation.  Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase.  The kinase activity of the complex requires the presence of BUR2.  Overexpression of BUR2 interferes with mitotic chromosome segregation (By similarity).
What are the official names of this protein?
Protein BUR2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACSA_SHELP
Sequence: MSTQSLYKVPSEIAANAHINDEKYKKMYQESVVNPEGFWREHGQRIDWMKPFTKVKKTSFDDHNLSINWFYDGTLNASVNCLDRHLADNADKLAIIWEGDDAADQRTLTYGELHTEVCKFANALRSQGVRRGDVVTVYMPMVPEAAVVMLACARIGAIHSVVFGGFSPDSIASRVIDGKSKVVITADEGVRGGRTIPLKANIDEALSHPDVTCVEKVIVLERTGNPVNWVEGRDIKWASLMETASEHCVAEEMGAEDPLFLLYTSGSTGNPKGVLHTTGGYLVYASMTHEYVFDYKEGEIYWCTADVGWITGHSYMVYGPLANGATILIHEGIPNYPTPARLGEMIDRHKVNILYTAPTLIRALMAEGKEQFDGFDGSSLRIMGSVGEPINPEAWRWYHEVIGHENCPIVDTWWQTETGGILISPLPGATDTKPGSATRPFFGVQPALVDNMGNIIDGAAEGNLVILDSWPGQMRTVYGDHDRFALTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVESALVAHEHVAEAAVVGYPHDIKGQGIYAYVTLTKGTQESEELRQELRQWVRKEIGALATPDLIQWAGGLPKTRSGKIMRRFLRKIAANEVTNLGDASTLADPAVIDTLIETRLNRSE
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ZIK1_HUMAN
Sequence: MAAAALRAPTQVTVSPETHMDLTKGCVTFEDIAIYFSQDEWGLLDEAQRLLYLEVMLENFALVASLGCGHGTEDEETPSDQNVSVGVSQSKAGSSTQKTQSCEMCVPVLKDILHLADLPGQKPYLVGECTNHHQHQKHHSAKKSLKRDMDRASYVKCCLFCMSLKPFRKWEVGKDLPAMLRLLRSLVFPGGKKPGTITECGEDIRSQKSHYKSGECGKASRHKHTPVYHPRVYTGKKLYECSKCGKAFRGKYSLVQHQRVHTGERPWECNECGKFFSQTSHLNDHRRIHTGERPYECSECGKLFRQNSSLVDHQKIHTGARPYECSQCGKSFSQKATLVKHQRVHTGERPYKCGECGNSFSQSAILNQHRRIHTGAKPYECGQCGKSFSQKATLIKHQRVHTGERPYKCGDCGKSFSQSSILIQHRRIHTGARPYECGQCGKSFSQKSGLIQHQVVHTGERPYECNKCGNSFSQCSSLIHHQKCHNT
What is the function of this protein?
May be a transcriptional repressor.
What are the official names of this protein?
Zinc finger protein interacting with ribonucleoprotein K, Zinc finger protein 762.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSPO4_MOUSE
Sequence: MRAPLCLLLLLAHAVDMLALYRRKKQAGTGLGGNCTGCVICSEENGCSTCQQRLFLFIRREGIRQYGKCVHDCPLGFFGIRGQEANRCKKCGATCESCFSQDFCIRCKRRFHLYKGKCLPSCPPGTLTHQSTRECQEECEPSPWGSWSPCIHNGKTCGSGWGLETRVREAGPAKQEETASCRVLSESRKCPIKRLCPGERNPRQKNRKDRRQRKDRKLERRPHQRGSQ
What is the function of this protein?
Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors.  Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.  Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway.
What are the official names of this protein?
R-spondin-4, Cysteine-rich and single thrombospondin domain-containing protein 4, Cristin-4, mCristin-4, Roof plate-specific spondin-4.
What is the protein family that this protein belongs to?
Belongs to the R-spondin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTS_CLOBM
Sequence: MISAKMVKDLREKTGAGMMDCKKALTECDGDLEKAVEVLREKGLAAAAKKSGRVAAEGIVSTYISEDMKNGSIVEFNCETDFVSVNELFVELANNLSKQAAFSNVSTAEELLEEKYIADESKLVKDVITELIAKLGENMNLRRIAKLSVDKGVIKSYIHGGGRIGVLVKLACEKEDAKLAEIAKDVAMQVAATNPLFLNRDGVDTDTLEKEKEIYRVQALNEGKPEKVVEKMVMGRINKYYKENCLVEQLWVKNGDYTITKYLQEQSKEIGADITVEAFVRYEKGEGIEKKEEDFAEEVQRQMNQGK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECM14_PARBA
Sequence: MRLFARLEVLAILACAVPIAAIPSFLSNSYPAHPAEGVSLFPQTQPQAPLGLWTRLRNTVIERLWRVPPQLNKNRPGKQGKFPLFSAPVSLRARYGDDVVLRFTIRNAEEVKALAEASNILFLDVWASTDEWVDIRLTKDVVPSLLGLLPQSLQTSHIPLIHDLPQTIYESYPSSSQRSSYDVQGFSPSTKHSSDITNIFFQDYQPFSVIVTWMRFLTSMFSSHVQIINIGSTFEGRDIPALQIGVWPANNPKPRKTVVVSGGSHAREWISVSTVNYVAYSLITSYAKSKHVAELLQQFDFIFIPTLNPDGYIYTWEVDRIWRKNRQETSLPFCPGVDLDRTWGFEWDGNITADNPCSESYPGEDPFAGVEAKQFSQWAKNQTAQNNIEFVAFIDLHSYSQQIRYPYSYSCLPNPPNLENLEELAIGIAKAIRLTNRETYEVSSACEGFMASQAKAKSDDPFPRIERTGGSALDWFYHDLNVKYSYQIKLRDRGSYGFLLPRENIVPTGQEMFNAVMVLGRFLSGHDGFGHLDWEDESQRPKADEDDIPSENELGENDDSWIPFDYRNHDDQNEGEGYDNDEWGFRRRRKG
What is the function of this protein?
Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.
What are the official names of this protein?
Inactive metallocarboxypeptidase ECM14.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Vacuole. Secreted.
Protein: RL28_ECO57
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DEOC_THEP1
Sequence: MIEYRIEEAIARYREYYEFKPARESAGIEDVRSAIEHTNLKPFATPDDIKKLCLEARENRFYGVCVNPCYVKLAREELEGTDVKVVTVVGFPLGANETRTKAHEAIFAVESGADEIDMVINVGMLKAKEWEYVYEDIRSVVESVKGKVVKVIIETCYLDTEEKIAACVISKLAGAHFVKTSTGFGTGGATAEDVHLMKWIVGDEMGVKASGGIRTFEDAVKMIMYGADRIGTSSGVKIVQGGEERYGG
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_BACCR
Sequence: MGKLYVFDHPLIQHKITYIRDKNTGTKDFRELVDEVASLMAFEITRDLPLKDIEIETPVSKATTKVIAGKKLGLIPILRAGLGMVDGILKLIPAAKVGHVGLYRDPKTLQPVEYYVKLPTDVEERDFIVLDPMLATGGSAAEAINSLKKRGAKQIKLMCIVAAPEGVKVVQEEHPDVDIYVAALDEKLNDHGYVVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ACKA2_NEIMA
Sequence: MSDQLILVLNCGSSSLKGAVIDRKSGSVVLSCLGERLTTPEAVITFSKDGNKRQVPLSGRNCHAGAVGMLLNELEKHELHDRIQAVGHRIAHGGEKYSESVLIDQAVMDELNACIPLAPLHNPANISGILAAQEHFPGLPNVGVMDTSFHQTMPERAYTYAVPRELRKKYAFRRYGFHGTSMRYVAPEAACILGKPLEDIRMIIAHLGNGASITAIKNGKSVDTSMGFTPIEGLVMGTRCGDIDPGVYSYLTSHAGLDVAQVDEMLNKKSGLLGISELSNDCRTLEIAADEGHEGARLALEVMTYRLAKYIASMAVGCGGVDALVFTGGIGENSRNIRAKTVSYLDFLGLHIDTKANMEKRYGNSGIISPTDSSPAVLVVPTNEELMIACDTAELVGIL
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase 2, Acetokinase 2.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.