PharMolix/UniProtQA huggingface dataset:
Protein: XRRA1_MACFA
Sequence: LAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLSDESVDWNGGGGSPQKEPQFMLQSKPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKSLKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFPSLCEFVFHNNPLVAHTRGVPPLLKSFLQERLGIHLIRRKTVKPKHHVLMSRKESRKVKTEIPKVPKQPLVLHHPQVTTNKSPSKDMLEPEAELAEDLPTTKSTFVESEMPTESLEGLSLSRRTFVPLPPICSDSTVHSEETLSHLSDTAVRLSPEHPSDEDSKSTESIFLTQVSELPSSIIHKDDLELKEKDQKKPPTAPREVKVTRRKLTTASLPSKYHGYEELLTAKPDPAFIEPKGIQKNAQALQHMLKHPLLCHSSKPKLDTLQKPYVPKEKRAQRIPIPPPRKTRTQLLDDIFIRLRDPRNITEAPLGAVLHRRTERRLVNHKQYLEAKRLLKEFQARYRQLVSGSLRTVFGTTPLPPACPALSESQPKFGRFLEFMDEFCQEPTASDSQG
What is the function of this protein?
May be involved in the response of cells to X-ray radiation.
What are the official names of this protein?
X-ray radiation resistance-associated protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CAHS8_HYPEX
Sequence: MSGRNVESHMERNEKVVVNNSGHADVKKQQQQVEHTEFTHTEVKAPLIHPAPPIISTGAAGLAEEIVGQGFTASAARISGGTAEVHLQPSAAMTEEARRDQERYRQEQESIAKQQEREMEKKTEAYRKTAEAEAEKIRKELEKQHARDVEFRKDLIESTIDRQKREVDLEAKMAKRELDREGQLAKEALERSRLATNVEVNFDSAAGHTVSGGTTVSTSDKMEIKRN
What is the function of this protein?
CAHS proteins are cytosolic heat soluble proteins that seem to contribute to the anhydrobiosis in tardigrades, but their specific mechanisms are yet to be identified (PubMed:28306513, PubMed:33545053).  It is possible that protection during anhydrobiosis might occur via the stabilization of vitrifying small molecules such as sugars, but not via the direct glass transition of CAHS proteins themselves (Probable).
What are the official names of this protein?
Cytosolic-abundant heat soluble protein 94063, CAHS 94063, Cytosolic abundant heat-soluble protein 8, Tardigrade-specific intrinsically disordered protein CAHS 94063, TDP CAHS 94063.
What is the protein family that this protein belongs to?
Belongs to the Cytosolic-abundant heat soluble protein (CAHS) family.
Protein: DRC2_HUMAN
Sequence: MPKKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIVNYQSNLLQPLSIRIAHPGDKQHPTT
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity).  Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes.  Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules (PubMed:24094744).
What are the official names of this protein?
Dynein regulatory complex subunit 2, Coiled-coil domain-containing protein 65, Testis development protein NYD-SP28.
What is the protein family that this protein belongs to?
Belongs to the DRC2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum basal body. Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: IOLC_BACC3
Sequence: MNPLIFKEDRPLDLIAVGRLCVDLNANETQRPMEETKTFTKYVGGSPANIAIGASRLGLQTGFIGKVSDDQMGRFITGYLKDNKINTDQIHIDCTGAVTGLAFTEIKSPEDCSILMYRDNVADLNLDPTEVSEDYIKQSKALLISGTALAKSPSREAVFLALEYAHKHDVVVFFDVDYRPYTWQSEAETAVYYNLAAEKSDVIIGTREEFDMMEKLLNYEQSNDQVTAERWFSHYAKIVVIKHGGDGSIAYTRDGQSHRGGIFKTKVLKTFGAGDSYASAFIYGLMQGLEIPQAMRLGGASASIVISKHSCSDAMPTRAEISAFMETAEELV
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase, 2-deoxy-5-keto-D-gluconate kinase, DKG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: TRUD_VIBC3
Sequence: MTDILSPLAYLCGKPTAKAKLKALPEHFQVNEVLGYSLTGHGEHLMVRIRKTGENTSFVANELAKACGVPSRAVSWAGLKDRHAVTEQWLSVHLPNGETPDFSAFLAQYPSIEILEVTRHDKKLRPGDLQGNEFVVTLSEVSDVAAVLSRLETVAELGVPNYFGSQRFGRHGNNLSEARRWGRDNVRSRNQNQRSLYLSAARSWIFNQIVSKRIEQGCFARFIEGDIALAEQQMFNVDGDLALWDQRLQAGEVAISAALAGDNALPTSGQALPLEQAELDAEPDLMALIRGNRMRHDRRAIALKAQNLSWQVQEDQITLRFSLDAGSFATSLVRELIEEIPVVRHYDQGHEQESRDSESED
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: TPIS_METMJ
Sequence: MDSPFVLVNLKTYQEGMGSNAHRIAAAAETVAKESGAVIGIAPAFTELHPMSHHYAIPVYAQHIDAITPGAHTGHILPEAVRSAGARGTLINHSERRLTLADIGACVESARRLHLETVVCTNNDATSAAAAALRPDYVAIEPPELIGSGVSVSKADPGIIERSVNAVRAVNPDVNVLTGAGIQSGECVKIAVDLGTCGVLLASSVVKADDPEAVLRDLVSLL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_MALP2
Sequence: MAKVDQITKKRAMTGNTRSHALNHSRRRWDLNLQKVKIYDENNNIVEVKVTARTLKGLKKNNKVVKVDYSKPAKVYGQNSPK
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CP11A_CAPHI
Sequence: MLARGLPLRSALVKACPPLLNTGREGWGHHRVGTGEGAGISTRTPRPYSEIPSPGDNGWINLYHFWRKKSSQRIHFRHIENFQKYGPIYREKLGNLESVYIIHPEDVAHLFKFEGSYPQRYDIPPWLAYHQYYQKPIGVLFKKSGAWKKDRVVLNTEVMAPEAIKNFIPLLNPVSQDFVSLLRKRIQQQGSGKFAGDIKEDLFHFAFESITNVMFGERLGMLEDTVNTEAQKFIDAVYKMFHTSVPLLNLPPELYRLFRTKTWRDHVAAWDTIFNKAEKYTEIFYQDLRQKTEFRNYPGILYHLLKSEKMLLEDVKANITEMLAGGVDTTSMTLQWHLYEMARSLNVQEMLREEVLNARRQAEGDISKMLQMVPLLKASIKETLRLHPISVTLQRYPESDLVLQDYLIPAKTLVQVAIYAMGRDPAFFSNPDKFDPTRWLGKDKDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILENFKIEMQQIGDVNTIFNLILTPDKPIFLVFRPFNQDPPQA
What is the function of this protein?
A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones.  Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule.  Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
What are the official names of this protein?
Cholesterol side-chain cleavage enzyme, mitochondrial, CYPXIA1, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450(scc).
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: MUTS2_ALKCK
Sequence: MERVQRVLEYNKMKQQLLEHVASSLGRQKVNELVPSTSLEEVRHLQDETAEAANVLRLKGHVPLGGISDVRPHIKRAAIGGVLSATELIEIASTLYGGKRVKQFIETIIEDGHIEVPILAGHVEQIEPLSPIEKAIKQCIDDNGYVLDSASTSLRTVRHQIRSYESGIKSKLDQLTRSSNTRKMLSDAIVTIRSDRYVLPVKQEYRGTFGGIVHDQSSSGATLFIEPAAIVTLNNQLTEAKAKEKREIERILRELSAKVAEESEQLLLNVDKLAQLDFICAKAYYAKAVKAVKPTLNDRGYLDLRQARHPLLPPDKVVPSDMAIGDQVRSLVITGPNTGGKTVTLKTIGLLTLMAQSGLFVPAAEETELAVFEHIFADIGDEQSIEQSLSTFSSHMKNIVSILNEMNENSLILFDELGAGTDPTEGAALAISILDHVYKRGALAVATTHYSELKGYAYNREGALNASVEFDVETLRPTYRLLVGVPGRSNAFAISRRLGLDERIIDQAKLQIDSDASQVEKMIASLEDSQKSAQSEWSRAEAVRREAEALKRDLEKRMASFEEMKEAALQKAEQKAEKVVAAAQENAELIISELRDLQKQGVAVKEHQLIEARKQLEEAAPKLVSKKRKQVKKQAEKAKRLPEPGDEVKVLSFNQKGTVVKKIGDNEYQVQLGIMKMAVPIDDIQLLEQERRQPEKAITTIRGNDAHVKAELDLRGERYEDAMRRVEKYIDDALLAGYHQVSIIHGKGTGALRKGVKQFVANHPRVKSARDGGMNEGGLGNTVIELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: SYN_SHESW
Sequence: MSIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLENYDNEVLKLTAGCSVVMTGDVVESPGAGQAFELQVTELEVTGWVDDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWVSTPLITASDCEGAGEMFRVSTLDMENLPRTSEGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTSRHLAEFWMVEPEVAFATLSDIAGLAEAMLKYAFNAVLTERMDDLQFFAQHVDKTVIERLQSFVSSDFAQVDYTDAVDILQKCGKTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDMRLAEMDLNKEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAQR6_MOUSE
Sequence: MLSLKMPQLLRVHQVPRVFWEEGIMSGYRCPTSSALDCVLSSFQMTNETVNIWTHFLPTWYFLWRLLALGSPGFRADPYHLPLLVFLLPACLYPFASCCAHTFSSMSPRARHICYFLDYGALSLYSLGCAFPYAAYSMPASWLHSRLHQLFVPAAALNSFLCTGLSCYSRFPELEYPGFSKALRTAAFAYPFLFDNLPLFYRLRLCWGGAHSCGRDALSSNHGYHLLCALLSGFLFAARLPERLAPGRFDYIGHSHQLFHICAVLGTHFQLEAVLADMGSRRAWLAVQEPTLGLGATVATLSLAVIGNLFIIAAFTASLLRMPGPCPLLQGSPLEEGLQAKQQ
What is the function of this protein?
Plasma membrane progesterone (P4) receptor coupled to G proteins.  Seems to act through a G(s) mediated pathway.  Involved in neurosteroid inhibition of apoptosis.  May be involved in regulating rapid P4 signaling in the nervous system.  Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone.
What are the official names of this protein?
Membrane progestin receptor delta, mPR delta, Membrane progesterone P4 receptor delta, Membrane progesterone receptor delta, Progesterone and adipoQ receptor family member 6, Progestin and adipoQ receptor family member 6, Progestin and adipoQ receptor family member VI.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU159_YEAST
Sequence: MSSLKDEVPTETSEDFGFKFLGQKQILPSFNEKLPFASLQNLDISNSKSLFVAASGSKAVVGELQLLRDHITSDSTPLTFKWEKEIPDVIFVCFHGDQVLVSTRNALYSLDLEELSEFRTVTSFEKPVFQLKNVNNTLVILNSVNDLSALDLRTKSTKQLAQNVTSFDVTNSQLAVLLKDRSFQSFAWRNGEMEKQFEFSLPSELEELPVEEYSPLSVTILSPQDFLAVFGNVISETDDEVSYDQKMYIIKHIDGSASFQETFDITPPFGQIVRFPYMYKVTLSGLIEPDANVNVLASSCSSEVSIWDSKQVIEPSQDSERAVLPISEETDKDTNPIGVAVDVVTSGTILEPCSGVDTIERLPLVYILNNEGSLQIVGLFHVAAIKSGHYSINLESLEHEKSLSPTSEKIPIAGQEQEEKKKNNESSKALSENPFTSANTSGFTFLKTQPAAANSLQSQSSSTFGAPSFGSSAFKIDLPSVSSTSTGVASSEQDATDPASAKPVFGKPAFGAIAKEPSTSEYAFGKPSFGAPSFGSGKSSVESPASGSAFGKPSFGTPSFGSGNSSVEPPASGSAFGKPSFGTPSFGSGNSSAEPPASGSAFGKPSFGTSAFGTASSNETNSGSIFGKAAFGSSSFAPANNELFGSNFTISKPTVDSPKEVDSTSPFPSSGDQSEDESKSDVDSSSTPFGTKPNTSTKPKTNAFDFGSSSFGSGFSKALESVGSDTTFKFGTQASPFSSQLGNKSPFSSFTKDDTENGSLSKGSTSEINDDNEEHESNGPNVSGNDLTDSTVEQTSSTRLPETPSDEDGEVVEEEAQKSPIGKLTETIKKSANIDMAGLKNPVFGNHVKAKSESPFSAFATNITKPSSTTPAFSFGNSTMNKSNTSTVSPMEEADTKETSEKGPITLKSVENPFLPAKEERTGESSKKDHNDDPKDGYVSGSEISVRTSESAFDTTANEEIPKSQDVNNHEKSETDPKYSQHAVVDHDNKSKEMNETSKNNERSGQPNHGVQGDGIALKKDNEKENFDSNMAIKQFEDHQSSEEDASEKDSRQSSEVKESDDNMSLNSDRDESISESYDKLEDINTDELPHGGEAFKAREVSASADFDVQTSLEDNYAESGIQTDLSESSKENEVQTDAIPVKHNSTQTVKKEAVDNGLQTEPVETCNFSVQTFEGDENYLAEQCKPKQLKEYYTSAKVSNIPFVSQNSTLRLIESTFQTVEAEFTVLMENIRNMDTFFTDQSSIPLVKRTVRSINNLYTWRIPEAEILLNIQNNIKCEQMQITNANIQDLKEKVTDYVRKDIAQITEDVANAKEEYLFLMHFDDASSGYVKDLSTHQFRMQKTLRQKLFDVSAKINHTEELLNILKLFTVKNKRLDDNPLVAKLAKESLARDGLLKEIKLLREQVSRLQLEEKGKKASSFDASSSITKDMKGFKVVEVGLAMNTKKQIGDFFKNLNMAK
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm).  NUP159 plays an important role in several nuclear export pathways including poly(A)+ RNA, pre-ribosome, and protein export.
What are the official names of this protein?
Nucleoporin NUP159, Nuclear pore protein NUP159.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACPS_ENT38
Sequence: MAILGLGTDIVEIGRIEAVIARSGDRLARRVLSDNEWAIWETHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEAQKLAEKLGVVNMHVTLADERRYACATVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUMA_ECOL6
Sequence: MSNKPFHYQAPFPLKKDDTEYYLLTSEHVSVSEFEGQEILKVAPEALTLLARQAFHDASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKGQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSAETNLKTVKLASAKYYDELPTEGNEHGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQQIQLTQCTRCVK
What is the function of this protein?
Catalyzes the reversible hydration of fumarate to (S)-malate.  Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle.  Accounts for about 80% of the fumarase activity when the bacteria grow aerobically.  To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate.  Can also catalyze the isomerization of enol- to keto-oxaloacetate.
What are the official names of this protein?
Fumarate hydratase class I, aerobic, Fumarase A, Oxaloacetate keto--enol-isomerase, OAAKE isomerase, Oxaloacetate tautomerase.
What is the protein family that this protein belongs to?
Belongs to the class-I fumarase family.
Protein: GATB_BRAHW
Sequence: MEYEAVIGLEVHVQLNTKTKAFCSCPNTFGAPANTLTCPRCQAHPGTLPIVNKEMVHKTIKAGLATNCTIQKKSRFARKHYFYPDLPSYYQITQMDEPICTEGHLDITVLNDDGSSYNKSIRINRIHMEEDAGKLVHDDTGRPLSYVDLNRAGCCLIECVSEPDISTGEEAYQYLTELKKIFKYIDVSDCNMEEGSLRCDANVSIRPKGSTELGTKTEVKNMNSFRNVRLAIDYEIKRQIKALNNGEKILQETRLYDAKENTTKGMRSKEGAADYRYFPDPDIPLLVLKDEEIEQAKKELPELPQQKRERLKKDYDLPDQDIVVLTEDAALADYYESAVKAYPKQPKKISNWIMVEVNAYLNKKLQTIKDFKPKAEHIAEIFKLIDEGVISGKIAKEIFEDMCETGEAPSAIVEKKGIKQVSDTGELETIIRKVLEENPKSVADFKAGKEKSFGFLVGQTMKATKGQGNPKLVNEVLRKILSE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: CAIC_ECOSM
Sequence: MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESAWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDQQHRLREVMFYLNLSAQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
What is the function of this protein?
Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle.  Also has activity toward crotonobetaine and gamma-butyrobetaine.
What are the official names of this protein?
Crotonobetaine/carnitine--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ACLP_MOUSE
Sequence: GVYMEIGRCRXEAXRRRKEAV
What are the official names of this protein?
Putative sperm adenylate cyclase.
Protein: TAM_YERPG
Sequence: MQDWDPDLYRQFEAERTRPATDLLAHITITSPQFISDLGCGPGNSTELLHRRFPDAQLVGIDHSQAMLASAQQRLPHCTFIEADIHQWRPSQPQNLIYANASLQWLTDHPHLFPSLLSQLAPRGVLAVQMPDNLDQPSHRAMREVAENGPWQQTLQEAGATRAKVLSANHYYDLLAPHAERVDIWRTTYYHPMPSAQAIVDWLRATGLRPYLAPLTEAMQLAFLQNYLAIIDKAYPARTDGRRLLAFPRLFIVAHAQR
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TONB_HAEIN
Sequence: MQQTKRSLLGLLISLIAHGIVIGFILWNWNEPSDSANSAQGDISTSISMELLQGMVLEEPAPEPEDVQKEPEPEPEPGNVQKEPEPEKQEIVEDPTIKPEPKKIKEPEKEKPKPKGKPKGKPKNKPKKEVKPQKKPINKELPKGDENIDSSANVNDKASTTSAANSNAQVAGSGTDTSEIAAYRSAIRREIESHKRYPTRAKIMRKQGKVSVSFNVGADGSLSGAKVTKSSGDESLDKAALDAINVSRSVGTRPAGFPSSLSVQISFTLQ
What is the function of this protein?
Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates.  It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.  Required for heme utilization and virulence.
What are the official names of this protein?
Protein TonB.
What is the protein family that this protein belongs to?
Belongs to the TonB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: NADD_DICT6
Sequence: MKIGILGGTFDPIHYGHLWFAEYARERFKLDKVFFIPNKIPPHRETPLATSKQRYEMVLLATLSNPCFEVLPIELEREGISYMVDTIRDLSSCFSFDELYLLLGNDAFRDFLKWKEPYKIIEKASIIVGSRGIEDYSSDLKNFIKNFENKIFFLDFPYYPISAKEIRERVKRGLSIKYLVPESVEDYIIKNGIYL
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: CAEG_CONBE
Sequence: SDGRDAAVIYTESDVIARGDCKPCMHPDCRFNPGRCRPRE
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Bt14.16.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KKX29_PANIM
Sequence: VDACYEACMHHHMNSDDCIEACKNPVPP
What is the function of this protein?
Reversibly blocks voltage-gated potassium channels Kv1. 2/KCNA2 and Kv1. 3/KCNA3.
What are the official names of this protein?
Potassium channel toxin kappa-KTx 2.9, Potassium channel-blocking toxin 6, Pi6.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Gamma-KTx 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3_PECAS
Sequence: MGQKVHPNGIRLGIVKPWNSTWYANTKEFADNLDSDFKVRKYLTKELEKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPSAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: REM7_ARATH
Sequence: MADPVLQSPKNSHFFQPLLPGFDSYLNIPVKFFSKRIQGRNEGRTVELRTDASEKTWQVKIQGRRLTVGWKEFASAHDFRVGDIIVFRHEGSLVFHVTALGPSCCEIQYVPSCNNQENISNLSMKQSIKTELESSLDEDKVNMGKFPRKKHVKKRIPEAEAKSFSSDKSCFVAHVTDSNLREDTLFLPRKFDRSDGLIKGSNKIVLMNEEARTWTLILKFRNSSRTFYMRGGWTSFSMSMGLNLEIPSRLN
What are the official names of this protein?
B3 domain-containing protein REM7, Auxin response factor 25, Protein REPRODUCTIVE MERISTEM 7.
What are the subcellular locations of this protein?
Nucleus.
Protein: DIDLB_ECHCA
Sequence: NSVNPCCDPQTCKPIEGKHCISGPCCENCYFLRSGTICQRARGDGNNDYCTGITPDCPRNRYN
What is the function of this protein?
May bind to both alpha-IIb/beta-3 (ITGA2B/ITGB3) and alpha-V/beta-3 (ITGAV/ITGB3) integrins, and may inhibit platelet aggregation.
What are the official names of this protein?
Disintegrin schistatin-like subunit B.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_LARHH
Sequence: MLLWLADWLGEYVRAFNVFNYVTLRAVLASLTALGIGLALGPWVIRKLAELKVGQAVRTDGPQTHLVKTGTPTMGGTLILLSIGITTLLWADLTNKYVWLLLAVLFGTGAIGFYDDWRKVVYKDPKGISARAKMFWQSAIAIFAGIYLISTASLPAATELIVPFFKHVIYPFGVVGFCILTYFVIVGTSNAVNLTDGLDGLAAMPVVMVSAALAVFAYVAGNSVFASYLSLPHIPGAHEVAVFCAAMAGACLAFLWFNAYPAQVFMGDVGALALGAALGTVAVIVRQEIVLFVMGGLFVMEALSVMIQVASFKLTGKRVFRMAPLHHHFELKGWKETQVVVRFWIITMMLVLAGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.