PharMolix/UniProtQA huggingface dataset:
Protein: FIXP_AZOC5
Sequence: MSTSHESHHAPVDGAGGPSTTGHEWDGIQELNNPLPRWWLWTFYATIIWAFGYWVAYPAWPLVSNYTSGVLGWNSRSAVVEQISDLQKLRAASSAKLANVPLEDIEKNPELLSLARAEGKVAFADNCAPCHGAGGGGAKGFPNLNDDDWLWGGTLAQIQQTITHGIRSGDDEGHQGNMLAFGSILSKADISNVADYVRSLSGAAPGDTPAAKKGAEIFAANCATCHGENGKGNQELGSKNLTDGIWLYGGDKATIVQTITNGRGGVMPAWGPRLSPTTIKALTVYVHTLGGGQ
What is the function of this protein?
C-type cytochrome.  Part of the cbb3-type cytochrome c oxidase complex.  FixP subunit is required for transferring electrons from donor cytochrome c via its heme groups to FixO subunit.  From there, electrons are shuttled to the catalytic binuclear center of FixN subunit where oxygen reduction takes place.  The complex also functions as a proton pump (By similarity).
What are the official names of this protein?
Cbb3-type cytochrome c oxidase subunit FixP, Cbb3-Cox subunit FixP, C-type cytochrome FixP, Cyt c(FixP), Cytochrome c oxidase subunit III.
What is the protein family that this protein belongs to?
Belongs to the CcoP / FixP family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ACPH_SHIDS
Sequence: MTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSLPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLNAHYAALETRFWQFYPRMMAQVSRKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Putative acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: Y1265_MYCTU
Sequence: MVLARPDAVFAPARNRCHVSLPVNAMSLKMKVCNHVIMRHHHMHGRRYGRPGGWQQAQQPDASGAAEWFAGRLPEDWFDGDPTVIVDREEITVIGKLPGLESPEEESAARASGRVSRFRDETRPERMTIADEAQNRYGRKVSWGVEVGGERILFTHIAVPVMTRLKQPERQVLDTLVDAGVARSRSDALAWSVKLVGEHTEEWLAKLRTAMSAVDDLRAQGPDLPA
What are the official names of this protein?
Uncharacterized protein Rv1265.
Protein: Y050_RICCN
Sequence: MRQISVISLRLNCQCTINFFVMIPNNIKEMNSNPMEKLAFQDAISLISYMYHHAEDILKSSKSLLNQILTTTKEGLSTSWDDIKKTTSGNVEYDLWQMEKQVPESEIITEKAKSGQLRSIKISCFSVDCSKPL
What are the official names of this protein?
Uncharacterized protein RC0050.
Protein: UREF_YEREN
Sequence: MNASDLIRIMQFGDSVLPVGAFTFSNGVESAIQTGVVRDVPTLKGFVLTALKQAASCDGMGVVAAHRAVVADDRDGIIRADWAVNNRKLNEESRLMATRMGKKLAEMSIHVVEHPLISWWLEQIKNGNTAGTYPVTQAVVMAAQGIGQREVVVMHQYGVAMTILSAAMRLMRVTHFDTQHILFELNHDIEKFCDIAEIGDIDQMSSYVPIVDVLAAVHVKAHVRLFSN
What is the function of this protein?
Expression of the urease operon increases the likelihood of bacterial survival by contibuting to acid resistance in vitro and in vivo in BALB/c mice.  Y. enterocolitica enters the body via an oral path and must survive the acidic stomach before being able to colonize the intestinal mucosa (PubMed:7558281).
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_PERMH
Sequence: MEKEISKVSRIKGELRVPSDKSISHRSIILTSLADGVSVVKNFLKAGDTLTTLNVYRKLGVSIIEEKGVLKIKGVNLKGFKEPEDILDMGNSGTTTRLTLGLLSGQEFFSALTGDDSLRQRPMGRVADPLRSMGAKIDGRQDGKLLPLSVRGSSLKGIQFYNKRSSAQVKSALLIAGLLAEGKTKVTEPYISRDHTEKMLDAMGADIHIERDDEYSVTISGSKKLEGIEIDVPADPSSAAFFAAAAVLIPDSELLLKDVLINPTRDGFFRKLKEMGGDIRYTNIREKAKEPVADIYVRYSPDLKGIRIKKEDVPSMVDEIPLLSIVATQAEGETIITGAEELRVKESDRIKAVVENLKNLGIDVEELPDGMVIKGKQKVKGGVVDSYKDHRIAMGFSILGLISEEGIKIKDADSVFISYPEFYEHLERIISN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOC90_ARATH
Sequence: MKGFKDWVFALSNSMASSRPLLGSDPFFRDPHQEQDNHSQAPAAPQPVTLSEPPCSTSSDLEILPPLSQQQVPLESLYQSSIDLNGKKHNPLAKIGGLQVQFLRLVQRFGQSQNNILVSKVLYRVHLAMLIRAEESELKNVKLRQDRAKALAREQESSGIPELDFSLRILVLGKTGVGKSATINSIFGQPKSETDAFRPGTDRIEEVMGTVSGVKVTFIDTPGFHPLSSSSTRKNRKILLSIKRYVKKRPPDVVLYLDRLDMIDMRYSDFSLLQLITEIFGAAIWLNTILVMTHSAATTEGRNGQSVNYESYVGQRMDVVQHYIHQAVSDTKLENPVLLVENHPSCKKNLAGEYVLPNGVVWKPQFMFLCVCTKVLGDVQSLLRFRDSIGLGQPSSTRTASLPHLLSVFLRRRLSSGADETEKEIDKLLNLDLEEEDEYDQLPTIRILGKSRFEKLSKSQKKEYLDELDYRETLYLKKQLKEECRRRRDEKLVEEENLEDTEQRDQAAVPLPDMAGPDSFDSDFPAHRYRCVSAGDQWLVRPVYDPQGWDRDVGFDGINIETAAKINRNLFASATGQVSRDKQRFTIQSETNAAYTRNFREQTFSVAVDLQSSGEDLVYSFQGGTKLQTFKHNTTDVGVGLTSFGGKYYVGGKLEDTLLVGKRVKLTANAGQMRGSGQTANGGSFEACIRGRDYPVRNEQIGLTMTALSFKRELVLNYGLQTQFRPARGTNIDVNINMNNRKMGKINVKLNSSEHWEIALISALTMFKALVRRSKTEMTEENEEEKIVNFLVS
What is the function of this protein?
GTPase involved in protein precursor import into chloroplasts.  Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis.  Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast.
What are the official names of this protein?
Translocase of chloroplast 90, chloroplastic, AtToc90, 90 kDa chloroplast outer envelope protein, Plastid protein import 4.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. TOC159 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Single-pass membrane protein. Cytoplasm. Note=Cycles between the cytoplasm and chloroplast, probably as a soluble preprotein receptor. The anchoring to the chloroplast outer membrane required the GTPase activity and GDP. May contain beta barrel transmembrane regions (Probable).
Protein: PLH24_FORAG
Sequence: MKKLWLMGLLLASFFTTVAQNNAQTKSNSDEEIDKKVATLISQMTLDEKIAEMTQDAPANERLGIPSMKYGEALHGLWLVLDYYGNTTVYPQAVAAASTWEPELIKKMASQTAREARALGVTHCYSPNLDVYAGDARYGRVEESYGEDPYLVSRMGVAFIEGLQGTGEEQFDENHVIATAKHFVGYPENRRGINGGFSDMSERRLREVYLPPFEAAVKEAGVGSVMPGHQDFNGVPCHMNTWLLKDILRDELGFDGFIVSDNNDVGRLETMHFIAENRTEAAILGLKAGVDMDLVIGKNVELATYHTNILKDTILKNPALMKYIDQATSRILTAKYKLGLFDAKPKKIDTETVETGTDEHREFALELAEKSIIMLKNDNNLLPLDVSKIKSLAVIGPNAHEERPKKGTYKLLGGYSGLPPYYVSVLDGLKKKVGEHVKINYAKGCDIDSFSKEGFPEAISAAKNSDAVVLVVGSSHKTCGEGGDRADLDLYGVQKELVEAIHKTGKPVIVVLINGRPLSINYIAENIPSILETWYGGMRAGDAVANVIFGDVNPGGKLTMSFPRDVGQVPVTYLERPDFIGSGKGQYRFSDKTPLFPFGFGLSYTTFKYGTPKLDNTSIAANGTTTVSVEVTNTGKVTGDEVVQMYVRDDYASVGRYLKMLKGFKRITLKPGETKTVSFKLGFDELNILNQDLKKVVEPGTFTISVGASSKADDLKTVSLTVK
What is the function of this protein?
Xylosidase involved in ulvan degradation (Ref. 2, PubMed:31285597).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).  Beta-xylosidase converts Xyl-Rha3S, a product of alpha-L-rhamnosidase acting on Rha-Xyl-Rha3S oligosaccharides, further to Xyl and Rha3S (PubMed:31285597).  The enzyme is able to degrade 4-methylumbelliferyl-beta-D-xylopyranoside (MUX) in vitro (Ref. 2).
What are the official names of this protein?
Beta-xylosidase, Glycosyl hydrolase 3 family protein P24, P24_GH3, Polysaccharide utilization locus H protein P24, PUL H protein P24.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MET18_YEAST
Sequence: MTPDELNSAVVTFMANLNIDDSKANETASTVTDSIVHRSIKLLEVVVALKDYFLSENEVERKKALTCLTTILAKTPKDHLSKNECSVIFQFYQSKLDDQALAKEVLEGFAALAPMKYVSINEIAQLLRLLLDNYQQGQHLASTRLWPFKILRKIFDRFFVNGSSTEQVKRINDLFIETFLHVANGEKDPRNLLLSFALNKSITSSLQNVENFKEDLFDVLFCYFPITFKPPKHDPYKISNQDLKTALRSAITATPLFAEDAYSNLLDKLTASSPVVKNDTLLTLLECVRKFGGSSILENWTLLWNALKFEIMQNSEGNENTLLNPYNKDQQSDDVGQYTNYDACLKIINLMALQLYNFDKVSFEKFFTHVLDELKPNFKYEKDLKQTCQILSAIGSGNVEIFNKVISSTFPLFLINTSEVAKLKLLIMNFSFFVDSYIDLFGRTSKESLGTPVPNNKMAEYKDEIIMILSMALTRSSKAEVTIRTLSVIQFTKMIKMKGFLTPEEVSLIIQYFTEEILTDNNKNIYYACLEGLKTISEIYEDLVFEISLKKLLDLLPDCFEEKIRVNDEENIHIETILKIILDFTTSRHILVKESITFLATKLNRVAKISKSREYCFLLISTIYSLFNNNNQNENVLNEEDALALKNAIEPKLFEIITQESAIVSDNYNLTLLSNVLFFTNLKIPQAAHQEELDRYNELFISEGKIRILDTPNVLAISYAKILSALNKNCQFPQKFTVLFGTVQLLKKHAPRMTETEKLGYLELLLVLSNKFVSEKDVIGLFDWKDLSVINLEVMVWLTKGLIMQNSLESSEIAKKFIDLLSNEEIGSLVSKLFEVFVMDISSLKKFKGISWNNNVKILYKQKFFGDIFQTLVSNYKNTVDMTIKCNYLTALSLVLKHTPSQSVGPFINDLFPLLLQALDMPDPEVRVSALETLKDTTDKHHTLITEHVSTIVPLLLSLSLPHKYNSVSVRLIALQLLEMITTVVPLNYCLSYQDDVLSALIPVLSDKKRIIRKQCVDTRQVYYELGQIPFE
What is the function of this protein?
Key component of the cytosolic iron-sulfur protein assembly (CIA) machinery that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity.  Acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as RAD3/XPD and DNA2, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription.
What are the official names of this protein?
DNA repair/transcription protein MET18/MMS19, Methyl methanesulfonate-sensitivity protein 19.
What is the protein family that this protein belongs to?
Belongs to the MET18/MMS19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSAA_SYNS9
Sequence: MTISPPERGSDAKSQVEKVDNPATFELFGKPGHFDRALAKGPKTTTWVWNLHANAHDFDAHTSDLQEVSRRIFSAHFGHLAVIFIWLSGAFFHGARFSNYSGWLADPTHVKPSAQVVWPIFGQEILNGDMGAGFNGIQITSGLFHVWRGWGITSETQLMALAIGALVMAGLMLNAGVFHYHKSAPKLEWFQNVESMLNHHLAGLLGLGSLSWAGHLIHVSLPVTKLMDAIDAGEPLVLNGTTIASAADIPLPHEFFNQDLLAQLYPGIGSGISAFFSGNWAAYGDFLTFKGGLNPVTGSLWMTDIAHHHVAIAVLFIVAGHMYRTNWGIGHSIKEIHEGQKGDPLLFPAPNGHDGLYEFMTTSWHAQLAVNLAMLGSLSIIVAQHMYAMPPYAYMAVDYPTQIGLFTHHIWIGGFLIVGGAAHAAIAMVRDYDPAKHIDNVLDRVLKARDAIISHLNWVCIWLGAHSFGLYIHNDTMRALGRPQDMFSDQAISIQPIFAQWIQNAHAAAAGSTAPNALAGVSEVFNGSVVAVGGKVAAAPMPLGTADFMVHHIHAFTIHVTVLILLKGVLYARSSRLIPDKANLGFRFSCDGPGRGGTCQVSAWDHVFLGLFWMYNSLSIVIFHFSWKMQSDIWGTVNADGSVAHITNGNFAQSAITINGWLRDYLWAQAVQVINSYGSSTSAYGIMFLGAHFIWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIIQGRAVGVAHYLLGGIATTWAFFHAHILVVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: GON3_CLUPA
Sequence: QHWSYGWLPG
What is the function of this protein?
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
What are the official names of this protein?
Gonadoliberin-3, Gonadoliberin III, Gonadotropin-releasing hormone III, GnRH-III, Luliberin III, Luteinizing hormone-releasing hormone III, LH-RH III.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPB_STAS1
Sequence: MKILLIGYGAMNQRVARLAEEKNHEIVGVIVRNSEKHYPYPTFEHISEATEADVAIDFSNPELLLPLLEEDFNLPVVIATTGEKEQIIDKLKALSTDMPVFFSANMSYGVHALTKILEAAVPLLQDFDIELTEAHHNKKVDAPSGTLVKLYDVIESLRETTTPVYDRHETTEKRTQDEIGIHSIRGGTIVGEHDVLFAGTDETIEITHRAQSKDIFANGAISAAEKLVQNKNGYYTFDNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB98_ARATH
Sequence: METCNGLMRKNKRQKVSRNSDWSKLCPDVLRKIYETLRSPVDSHRAKIVCSNWYSVWKTCVKRPLCPLRIIHQGDSPTVGDGNRKLMGFSYNSYCMASSGNWLLMVDRCLKFYIYNLLTKERIDLPSMESKIRGGQVSFKSKSNNYNFGYLVGPSRKDDIVPYDYEAVEWKKSLAVLWVDETTGDYAVAWTFMRQYLFSYIKGDYSWCNLNHNGKSLVLFDMACENNKLYLLTMDHHIKIFNFYGDFLTGEQNLYPFNFVEDPSEYVWKRKIVIRRSGEVLIVLSLKKKVQNEEKLLFYIFKMNLESRKWERVYCIGDEMLIFGRGVTALALEDLDDGIKSNSIYFVGEDVWPDHQEHEHRVSNCGFFDIATSKIEWPKKIYCFINQNQWFVGGVAY
What are the official names of this protein?
Putative F-box protein At2g04810.
Protein: FABPM_CHICK
Sequence: KLVDTANFDDYMKALGVGFATRQMAGLTKEISFKLDEEFDETTADDRHVKKLILTLTMGNVVSTRTYPTTI
What is the function of this protein?
May be involved in the regulation of smooth muscle contraction by transporting polyunsaturated fatty acids (e. g.  arachidonic acid).
What are the official names of this protein?
Fatty acid-binding protein, smooth muscle, SM-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein: TIG_STRCO
Sequence: MKSAVETLNPTRVRLTVEVPFEELKDSLDAAYKKINQQVTVKGFRKGKIPARVIDQRFGRGAVLEEAVNDALPKFYTDAVNEAELNPLGQPEVDITELKDGETLNFTAEVDIRPSIEIPDYSGIEVEVDAVEVTDEDVEKSVEQLRERFASTSPVERAAADGDVLTLDLQAKVDGEILEDGVADGVSYTIGSGELLDGIDEAVKGLEAGGEATFTSELKGGSAAGKEAEVTVKVSQVAARELPELDDDFAQLASEFDTLEELQADSRKRLANMKQYDQATQAQERVLDKLLELVEVPVPEKLLEDEINTRKHNLEHHQLGQMGLDLEKYLELQGKTAEEFETETREAAVKGIKTQFVLDELVKQEKLNVSQEELTEHLMRRAASSGMSPDQFAQAVVEQGQVPLLVGEVARGKALAAVVEKATVKDTNGEIVDLDDEEDEETEAAEADATEAADAEKADDKAEEKTEG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: METAA_PETMO
Sequence: MPIKIPENLPAAEVLREENIFIMTEERAAHQDIRPLEIVILNLMPNKIVTETQLLRLLGNTPLQINVVLLRMVSHSHKNVSQEYLDTFYKSFDQISHRKFDGLIITGAPVETLDFEQVDYWEELKEVMDWSKKNVFSTLHICWGAQAGLYYHYGINKYHVSKKIFGVFEHSVSCEDSPLVRGFDDTFWVPHSRHTQIKREDIEPIKELMILSESKKAGVYLVERKDGRQVFVTGHPEYDPEVLKKEYYRDLKKGMDIDIPVNYFPHDDPEKRPVVRWRSHAYILFNNWLNYYVYQQTPYNLDNIDQAIL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_PSEPF
Sequence: MSAPRETIAAVATAQGRGGVGIVRISGPLASVAAKAISGRELKPRFAHYGPFFSDNQQVLDEGLALYFPGPNSFTGEDVLELQGHGGPIVLDMLLKRCLELGCRLARPGEFSERAFLNDKLDLAQAEAIADLIEASSAQAARNALRSLQGAFSQRVHNLTEQLIGLRIYVEAAIDFPEEEIDFLADGHVLSMLDKVRNELSTVLREAGQGALLRDGMTVVIAGRPNAGKSSLLNALAGREAAIVTEIAGTTRDILREHIHIDGMPLHVVDTAGLRDTDDHVEKIGVERALKAIGEADRVLLVVDATAPEAADPFALWPEFLETRPDPAKVTLIRNKADLTGEPIALEVSDDGHVTISLSAKSAGEGLDLLRDHLKACMGYEQTSESSFSARRRHLEALRHASDALEHGRAQLTLAGAGELLAEDLRQAQQSLGEITGAFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_ANAD2
Sequence: MKKVTGQIKLQLPAGKANPAPPVGPALGQHGVNIMEFCKQFNAATQAQAKEALIIPVIITVYQDRSFTFVLKTPPAAILLKKAAGLHTEKKKGSGAHKPGKEKVGQVTRKQVEQIAKTKMQDMTAGTLEAAMRTVEGTALSMGIEIVG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RELB_HUMAN
Sequence: MLRSGPASGPSVPTGRAMPSRRVARPPAAPELGALGSPDLSSLSLAVSRSTDELEIIDEYIKENGFGLDGGQPGPGEGLPRLVSRGAASLSTVTLGPVAPPATPPPWGCPLGRLVSPAPGPGPQPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGICRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGMPDVLGELNSSDPHGIESKRRKKKPAILDHFLPNHGSGPFLPPSALLPDPDFFSGTVSLPGLEPPGGPDLLDDGFAYDPTAPTLFTMLDLLPPAPPHASAVVCSGGAGAVVGETPGPEPLTLDSYQAPGPGDGGTASLVGSNMFPNHYREAAFGGGLLSPGPEAT
What is the function of this protein?
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis.  NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52.  The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.  Different dimer combinations act as transcriptional activators or repressors, respectively.  NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors.  NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family.  In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus.  NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators.  RELB neither associates with DNA nor with RELA/p65 or REL.  Stimulates promoter activity in the presence of NFKB2/p49.  As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.  Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer in a CRY1/CRY2 independent manner.  Increased repression of the heterodimer is seen in the presence of NFKB2/p52.  Is required for both T and B lymphocyte maturation and function (PubMed:26385063).
What are the official names of this protein?
Transcription factor RelB, I-Rel.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome.
Protein: COQ7_XANOP
Sequence: MTQTSPSRLHSPLDRLLVEAQRALDTVFGNPPAERPNPAADTPDIALDPEQRRHAAGLMRINHVGEVCAQGLYFGQAAVARDAHTQHHLLEAAQEETDHLAWCADRLHELDSRPSLLNPLWYAGSYALGALAGLRGDDWSLGFVVETERQVEAHLDEHLETLPDIDQRSRAILRVMKIDEARHADQAEQAGARQLPAPIPGAMALASKLMKTVAYRL
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SPX6_ORYSJ
Sequence: MKFGKLLKRQIEQSLPEWRDKFVSYKELKRIVASISGSPADEAAFVAALAADIDKIDSFFLEQEEEFVIRHRELQEAIKKAAEAAAEVAGIRREIVDFHGEMVLLLSYSSINYIGVGKILKKHDKRTGGALAAPVAEAVRERRHFFKTETVSRMVRECEAMMAEAAVLPAEAAPEALAAAAEHGIFRNTVAALLTMEDVRRGSSTHGRHSLPPLTLPDSDWLRSFQPPSPIPIQ
What is the function of this protein?
May be involved in maintaining cellular Pi homeostasis when plants are exposed to an external change in Pi.
What are the official names of this protein?
SPX domain-containing protein 6, Protein SPX DOMAIN GENE 6, OsSPX6.
Protein: EIF3M_DROPE
Sequence: MTSHPVFIDLSLDEQVQELRKYFKKLGAEISSEKSNKGVEDDLHKIIGVCDVCFKDGEPSQIDGILNSIVSIMITIPLDRGENIVLAYCEKMTKAPNQPLGKVCLQSLWRLFNNLDTASPLRYHVYYHLVQVAKQCEQVLEVFTGVDQLKTQFANCPPSSEQMQKLYRLLHDVTKDTNMELSSKVMIELLGTYTADNACVAREDAMKCIVTALADPNTFLLDPLLALKPVRFLEGDLIHDLLSIFVSDKLPSYVQFYEDHKEFVNSQGLNHEQNMKKMRLLTFMQLAESNPEMTFDTLTKELQITEDEVEPFVIQVLKTKLVRARLDQANRKVHISSTMHRTFGAPQWEQLRDLLQAWKENLSSVRDGLTNVSSAQLDLARTQKLIH
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m, Transport and Golgi organization protein 7, Tango-7.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: RUVB_ECOUT
Sequence: MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: IPYR_CHLPN
Sequence: MSKKPLYVAHPWHSPTLTQDNYESLCCYIEITPYDSVKFELDKATGLLKVDRPQKFSNFCPCLYGLLPQTYCGTASGNYSGEQTRREGIQGDKDPLDVCVLTEKNIHHGNILLQARPIGGLRIIDSGEADDKIIAVLEDDLVFAEIEDISDCPGTVLDMIQHYFLTYKATPNHLIKGSPAKIEIVGIYGKKEAQKVIQLAHEDYLSYIGDTAEVN
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.