PharMolix/UniProtQA huggingface dataset:
Protein: SODC_CRYGA
Sequence: MVKAVAVLKGDSPVTGVITFTQEKEGAPVTVSGDIKNLDANAERGFHVHEFGDNTNGCTSAGPHFNPHGKNHGAPSDSERHVGDLGNVKTDGNGVASVNISDKSLSLFGPYSIIGRTIVVHAGTDDFGKGGNAESLKTGNAGARAACGVIGISN
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPC6_MOUSE
Sequence: MPSWIRAVILPLSGLLLTLPAAADVKARSCSEVRQAYGAKGFSLADIPYQEIAGEHLRICPQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENFNTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDERVTAGTSNEEECWNGHSKARYLPEIMNDGLTNQINNPEVEVDITRPDTFIRQQIMALRVMTNKLKNAYNGNDVNFQDTSDESSGSGSGSGCMDDVCPTEFEFVTTEAPAVDPDRREEESSASKFSSSLISWSLVCMVLALQRLYR
What is the function of this protein?
Cell surface proteoglycan that bears heparan sulfate.  Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases.  Enhances migration and invasion of cancer cells through WNT5A signaling (By similarity).
What are the official names of this protein?
Glypican-6.
What is the protein family that this protein belongs to?
Belongs to the glypican family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side. SUBCELLULAR LOCATION: [Secreted glypican-6]: Secreted, extracellular space.
Protein: AAEA_ENT38
Sequence: MKTLTRNISRTAITVALVILAFIAISRAWVFYTESPWTRDARFSADIVAIAPDVAGLITAVNVRDNQLVKKDQVLFTIDQPRYQKALEESEADVAYYQALTTEKRREAGRRNKLGIQAMSREEIDQSNNLLQTVLHQLAKAEATRDLAKLDLERTVIRAPSDGWVTNLNVYTGEFITRGSTAVALVKQHSFYVLAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSIAAGVTNSSATRDSKGMATVDSNLEWVRLAQRVPVRIRLDDEQGNLWPAGTTATVVITGEKDRNASNDSLFRKIAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y839_RICCN
Sequence: MKLGYSWKYGPFELLTIAAKNGWNSVIKNADLMHIPLPQYLANKEYQKIDKQKFNSHKDILQESQISIRE
What are the official names of this protein?
Putative uncharacterized protein RC0839.
Protein: MDIII_MUSDO
Sequence: MNATDAESRKPENKPSSESSSSGSTSGSSDGEVSSKTYFKNNKSKVLSGQREVVLEVVRDLSYTICKEAEEKLVERFPRKDGSNEMLPKEDSINTNHNYTTDSNEHPVELTTKTEECKNTEKTKKKSFVRALSKDKQLSAYRSRSRSTRLSYSGHISRTHSVEKSLSRYKKSVLRNRRTSFGHGRDSSTTKRSVSRDKDNRLRRRIGSSRSHTRSHSRFRRSEKKLPSRSPRRIRSQERRHERRRSMSSDYERIALRRSEPIKRRDKDEFFKNNKKVSGDIKKGKGNDNGTVAELEAKITERQRKSLDILTSRTGGACLTPDKLRMIQAEITDKSSAAYQSIAREALKKYIHGYINKVNVDSVAVITRKLLKDNIVRGRGVLCHSIIQAQATSPTFTHVYAAMVAIINSKFPNIGELLLKRLVIQFKRAFGCNDKTVCLTSSHFIAHLVNQRVAHEILALEILTLLIESPTDDNVEVAITFLKECGMKLTEVSSDRVGGIFELLKNILHQGKLDKRVQYMIKVLFQVRRDGFKDHQSIIESLELVEEYAQFTHLLLLEDVTYPKDILNEFKFDDQYETNEEKYKALSKDILGSHASDSDGSFGSGSNSETALSDCDKVKNEVNDKYTSGDIIDETKPNLIALRRTIYLTLNSCLDYEECAQKLMKTQLKTCQQNEFCQILLDCCAEQRTYEKFYGLLTHRICKMNKSFIEPFKEIFKDICQTTHCLDTNRLRNISKFFAHLLFTDAISWDVLDCIKLTEDEAITSRCIFIKSFFQELVEYMGLYHFNKKLKTEVLAGTLAGLFPKDNPRNIRFSINFFTSIGLGGITNELCQLLKIAPKSAPSSSSSSSLSSELSAPSDDDSSSDSENKKKHKGKNKKMTKKKNPSKKKEKTKKFVGKNKIAAKNKTIKRRTDKDNSSSKDNFLKSESSSNESISLDSLSSELFAPSSYSSSESSNDSESKEKHKGKNKKMTKKKNPSNKKEKTKKKLSKNKKAPNKNTKKRMTEKDISSSESSISESKSLNCSASNQNENEKRKKRVTSKSRTKRVKMFKQCQWVDADNQRDIKRKKRAEYRYEPLVYRKRNEECLKKGAPNCXKDNYGNRQNHEISQRHDSEIKRRREERKKRHHEKNHSREYKRSKLGLCQREYFLYMCCQFYYPCTFQCLCQNCHFTFYS
What is the function of this protein?
Male determiner protein (M-factor) that controls male somatic sexual differentiation (PubMed:28495751).  Acts as a dominant factor that regulates the mRNA splicing of transformer (tra) and doublesex (dsx) transcripts and promotes expression of male splice forms of tra and dsx (PubMed:28495751).  Probably acts as a component of the spliceosome C complex required for mRNA splicing factor and exon-junction complex (EJC) assembly (By similarity).  Hinders eIF4AIII from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs (By similarity).
What are the official names of this protein?
Male determiner protein Mdmd(III), Male determiner encoded on chromosome III.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: PSTB2_LIGS1
Sequence: MEKIITTKDVHLYYGSKEALKGITLDFPDKGIHALIGPSGCGKSTYLRTLNRMNDMIENVKIEGEFKFKNQNIYDEKIDLVELRKKIGMVFQQPNPFPFSIYDNVTYGLRMAGIKDKRILDEKVETSLKQAAIWEEVKDNLNKNALALSGGQQQRICIARVLAVAPEVILLDEPTSALDPISTEKIEEMLLTLRDNYTCIMVTHNMQQASRISDTTSFFLSGNLVESNKTKKIFLNPDKEQTADYLSGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GAA1_YEAST
Sequence: MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMPSQAYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYENEQYGETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFSENPRAALRSWVEAYHTSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHGLPSDQLTNNNFWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFINNAYANISLFSEYNLVALLVWFVSLVISFVVSQAFLLIPSSGLLMTISMASCFLPLILSRKIHISEPLSYRLKNVAFLYFSLVSTSLLMINFAMALLIGTLAFPMTFVKTIVESSSEHEVTTQSSNPIKTEPKDEIELVENHMDTTPATPQQQKQKLKNLVLLILTNPFISITLFGLFFDDEFHGFDIINKLVSAWLDLKCWSWFVLCIGWLPCWLLILASSFESKSVVVRSKEKQS
What is the function of this protein?
Component of the GPI transamidase complex.  Required for a terminal step of GPI anchor attachment onto proteins.  Affects endocytosis.
What are the official names of this protein?
GPI transamidase component GAA1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RNPH_BRUMB
Sequence: MRPSKRAADEMRTISFERGVSKHAEGSCLVKFGDTHVLCTASLEEKVPGWMRNTGKGWVTAEYGMLPRSTGERMRREAAAGKQGGRTQEIQRLIGRSLRAVVDMQALGEMQITVDCDVIQADGGTRTAAITGGWVALHECLRWMEARQMVRVEKVLKDHVAAISCGIYEGVPVLDLDYAEDSVAETDSNFVMTGKGGIVEIQGTAEGVPFSEEEFGALMKLARSGIDRLVSLQKMAVA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: APAG_ECO57
Sequence: MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: THIP_BRUME
Sequence: MTATPARRTSLASPATKPVAGGLALAFLATLAGGALLALALEAGGGGFDAAANFDTYLWRVARFTIWQAVASSLLSVLFAIPIARALYAEARFPGRGLILRLFAQPLALPALVAVLGVTSIYGRNGLIAHISDMLGHPMQPDIYGIAGILIAHIFFNMPLAVRLLLAAYESIPDDHWKLAAQLGMGSRARFRLIDWPVIRRSLPGMIGLVFMLCVTSFTTVLTLGGGPRATTLEVAIYQSLHFDFDPARAVALTFTQLALTLLILLILRLTGRPSEEGFTQTATPRRYGSPRKTERLFNIIVIALGFLYVALPIAGVVVSGLTADLVRLLSERIVWHAIATSLALGFSAALLAVFLSLALVAAREATRNARIANIFDTGASLILVMPPIVIGAGWFILLRHFTDPFVMAPLMVVTVNAAMAMPFAVRLLRPAWDTAASRHNKLCSQLGIKGFNRLRLIDWPSIRRPCGMAFAFAMALSLGDLGTIALFGSDALVTLPYLLLQRMGSYRTFDAAGLALILGVLCLALMMIADRAAASRKEAFLQ
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Thiamine transport system permease protein ThiP.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LRA25_HUMAN
Sequence: MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAARAPDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMVGLRQLDMSLLCQLWGLYESIQDYKHLCQDLSFCQDLSSSLHSDSSYPPDAGLSDDEEPPDASLPPDPPPLTVPQTHNARDQWLQDAFHISL
What is the function of this protein?
Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TGF-beta.  Acts as an adapter that mediates the specific recognition of LIMK1 by CDC42BPA and CDC42BPB in the lamellipodia.  LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation.
What are the official names of this protein?
Leucine repeat adapter protein 25.
What is the protein family that this protein belongs to?
Belongs to the FAM89 family.
What are the subcellular locations of this protein?
[Isoform 3]: Cytoplasm. Cell projection, lamellipodium. Note=Co-localizes with CDC42BPA, CDC42BPB and LIMK1 in the lamellipodium.
Protein: PIC1_SCHPO
Sequence: MGSNGSELWFNKELEYSQQLTNGKMKEFFFLVSETMDWLNEHMLEVSKLQLESDIYELVRTPTKIKEKYSTPRLSPVHRCALPTPRMRLTSIQHQLEEAAVEGYKSGESNTVKEPKELHTATNTETQFDDDRDSTKLSSEYVKDDIVNKSTKGGVSPIKETRLPTNLPAFSPTSVERRFTEWNVPLRETSPSPSETADSPNKLPKQKHPAYSFVTLPKREEILKRPASLHSRVESTNSFINQLNRRRTKDNLTNNPEISLDEPIKALPSTTSDAPSSLLNTNVSSSPSKFRKFLSSVIPAKTDLSAKESLTSSTRLSTSYKTRKRSSGVAFSSETVTSSSKERKRSVENEMLKPHPTIFESPPEITSFDKSNAVEAEALTAKLKSNEERLPVSSQPGSDAKSQEFDFFEAKIPDSIAKLNELTASNENHYELKTYDRAERLRQKIQEVSSNKRLIPSTPPTKKPINAVLDAAKNSAAKDLHLAKMKLNNKNDESSLSPAKSHAVITQAPKIPLISTFTRLSTRKSSNDFNSSNSRPSSNALKSDANENTDSSLPPSKKEFIEKSLHKLSEPLHDDSRQNSDHNFAPHSRPIAIRVATASQRELEQTEKRKAKNGAANASNMESRSSENETHRFKKFYGKERELSNNEFPSRQTKTVTSANSSNIRDMEHTISDKPRSEPDAIPSSKSMHSNKPFEEKSEKPTTKRLVTNPSNVNASWHSNMLKRQEDLRKKKPLTDNGATSRHMLKSGLTRVTSKPTQRFANELAEDMSLAFHSTIPKKMEPDSVTSVTQPSVGSLRNNFDIGTTNSQNEDRKKKIAAQKNKNPVHGNVGLTNQHGFKTMHHNVNPFTKQNGIMKGKLPSSSTSQSNKPFIEKASMHAPAKGRNSSMQEPSSKSPLLKTPKSNYFPGYGSLSPNTSVELPEINSDYSDDSDDEGNKKKVNLPSWAESPELREQLKRQQKWDPDKIFGMIKPLQMDEYFRSKDRSKIRFRPRSSSADWSSQDRLTQAEIDNYKKNMGFL
What is the function of this protein?
Required for chromosome segregation and cytokinesis.  Has a role in sister chromatid cohesion and condensation.
What are the official names of this protein?
Inner centromere protein-related protein pic1, INCENP-related protein pic1.
What is the protein family that this protein belongs to?
Belongs to the INCENP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Associates with the elongating spindle during anaphase.
Protein: NDB4T_OPICY
Sequence: MKTQFAILMIAVVLMQMLVQTEGGILGKIWEGVKSLIGKRGLKKLDQLDDTFDSDLSDADVKLLREMFK
What is the function of this protein?
Amphipathic peptide with antimicrobial activity (PubMed:27917162).  Shows antifungal activity with MIC values ranging from 25 to 200 uM (PubMed:27917162).
What are the official names of this protein?
Amphipathic peptide OcyC2, Non-disulfide-bridged peptide 5.8, NDBP-5.8.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: ZAPB_ECO57
Sequence: MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQNAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: E4F1_DANRE
Sequence: MTEENNNTAATVTDQTEHSNIITIQTTLGDEDEDIHKCGKCLAEFSALDAFIQHKLSRSCKRTQDPQTNVVPNEGVSVEVRSSENECSSDETATANGEKQDAKVASGDKKRSRSTSEDESSSPSKVVWKLNTEGRYVCDICAKTFKTTNILRTHMFTHSDQKNFVCEMCETAFRTKGSLIRHKRRHTDERPYRCNQCGLAFRESGALTRHLKSLTPCTEKIRYSQCKEILVSKDGIRKEVQPSSPEPEKEQIPVVRVVEAGQEIIQIEVVEEVQQVASQPQTATVVEADNLICQAIINSGIALETEATEAAGQVEAQSPKAVLGAPETETRITEIQVTEECVETLAEETQDSSVKEVEPVQSKLYKCPHCERMFKTLNYLRVHVKGHVGYKPFKCLTCQKEFLTGYVLKKHMETHVSERRYKCGECGKQFKAIGHVREHMRAHSDERPYHCSFCDKSYKTKNALQVHHRTHADDKPYVCQHCSRGFREKSALVRHIRHHTGEKPFKCSKCGRGFAEHGTLNRHLRAKGGCFAQLKDCEHVVNSEEQEVTTESVSTTIVSDDPHAVLVEFSSVVADTQEYIIGAPAEEAAQGEEVAIIQDNQQQMDSHIMKVVQQIVSQSHGGHQIIVRNVTADETPGISDSGDTITIATPESLTEQVAMTLANAISDGTILTTTTEDTDETSHTTVTMVTAENVETIEQEEQYVIASPEEVEIQTVVVV
What is the function of this protein?
May function as a transcriptional repressor.  May also function as a ubiquitin ligase.  Functions in cell survival and proliferation through control of the cell cycle.
What are the official names of this protein?
Transcription factor E4F1, Putative E3 ubiquitin-protein ligase E4F1, RING-type E3 ubiquitin transferase E4F1, Transcription factor E4F.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=A small fraction is detected in the cytoplasm.
Protein: ARCH_THEAC
Sequence: MDSDDNRTLSYEVVDHESDIGVIVYGKTYEELFSNAVYAMADLIVDVSRLKENRKMHEVITGKTPEDIMVNLLSRVLFYLDTYYILYYRITSKYSDGELDAYFYGSEIPEGIEYRNVIKAVTYSDLAVKPEEGYAKIIFDL
What is the function of this protein?
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB.  Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation.  Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
What are the official names of this protein?
Protein archease.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: MRAY_NITEC
Sequence: MLLALFQWIAEDIRAFNVFSYITLRTMLAALTALSISFLIGPAMIRSLTTRKVGQSVRSDGPQSHLTKAGTPTMGGALILMAVIITTLLWADLSNRYIWLVLLTTLGFGAIGWVDDYRKVVQHNSKGLPASAKFFWQSIIALLVAVYLAMTAELPQHTDMIVPFFKEVAIPLGSFLFIILTYLVIVGSSNAVNLTDGLDGLAIMPTVMISGALAIFAYVAGHAIFAKYLGIPHIPSAGELAVFCGALAGAGLAFLWFNANPAEVFMGDVGALALGAALGVITVIVRQEIVLVIMGGVFVMEALSVMIQVASFKLFGRRVFRMAPLHHHYELKGWKENQVVVRFWIITIILVLIGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEM6_ERWT9
Sequence: MNTPDIAQVKRFLLNLQDEICQKLEQADGAARFAEDSWQRPGGGGGRSRVLRQGRVFEQAGVNFSHVHGDEMPASATAHRPELAGRSFEALGVSLVIHPENPYIPTSHANVRFFIAEKPGADPVWWFGGGFDLTPFYGFTEDAVHWHQTAFDLCLPFGAEVYPRYKKWCDDYFHLKHRNEQRGIGGLFFDDLNAHGFDQSFRFMQAVGRGFCDAYLPIVERRKALTWGERERDFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPREDSPEAALYRDFIVVKEWL
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_UREP2
Sequence: MMIKIISVGKLKQKAFVDLINDYLKRINHYLKCQEIVVSDEPEPVQISNKSLEQIKSKEASKIFKNINQNDFVIALIIESNIISSETLAKKIQQWLNTFSHDICFIIGGSNGLHESIYERANYHLSMSKMTFAHGLAKVMLCEQIYRALSILNNGKYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT03_PROWI
Sequence: MGQKTNPISLRLQNVNRNFDSCWYSDYFYAKCFSRDLYLNNYINTFFKLYRLPQARVCVNFGIQNIKVYPFFCIPKASRVSLAKNLGLFQHLSKAWNSSPKYFVSSKSKQLSQLKINDASLPVNNLNNNLFFNSSKHNEIRNKQNFFHNLELNKLNLSFKNSAYSDVKNYSFLENISAKLLLNFKEKSVINEVYYTTTNLGQIGNNISTNSIYSKQDMSDNSSKSLLKMLLREYYKSSDNKSSILYENKSPKSLENIFGKINEVSNINKKNLYLLNSETDNIPNLYKRKSKPTKFLRNEHNKVIEDKKTSLYFMPDSNQIKNDIYQGKISKISSISNNSKDSLTDYNLHLYQAYLHNILGNSKSLVSRNQFKYKNYIENFLSSQYNIDSQLFPFISKQNWQSAGFIADEIVYFIERRVSFSRIKNRILRQASMQSYVRGIRITCSGRVGGKSKKAQRATQECVKYGETSLHVFECKIDFASRIANTSFGLVGIKVWICFK
What are the official names of this protein?
Ribosomal protein S3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DNJB3_MOUSE
Sequence: MVDYYEVLGVPRQASAEAIRKAYRKLALKWHPDKNPEHKEEAERRFKQVAQAYEVLSDVRKREVYDRCGEVGEVGGGGAAGSPFHDAFQYVFSFRDPAEVFREFFGGHDPFSFDFFGGDPLENFFGDRRSTRGSRSRGAVPFSTSFTEFPGFGGGFASLDTGFTSFGSPGNSGLSSFSMSCGGGAAGNYKSVSTSTEIINGKKITTKRIVENGQERVEVEEDGELKSLIINGREQLLRINTQ
What is the function of this protein?
May operate as a co-chaperone of the male germ cell- and haploid stage-specific Hsp70 proteins.
What are the official names of this protein?
DnaJ homolog subfamily B member 3, DnaJ protein homolog 3, Heat shock protein J3, HSJ-3, MSJ-1.
Protein: TRUA_RICPU
Sequence: MYRYKITIEYLGTDLAGWQRQAGVMSVQQILEEAIYKFSGEQVILFGSGRTDAGVHAVGQVAHFDLSKYLEPHKIITAINYFARPYAVGVWNCELAPNNFHARFSATSRYYIYRIINRPCPSVIDLNRAWWISSPLDVPAMQQAAAYLLGKHDFTSFRASSCQSKSPIKTLTELNIIKEDEEIKLYLSAPSFLHHMVRNIVGSLVLVGKNIWQAEQIKDVLEAKDRKAAGPTAPASGLYFVKAAY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: Y2684_MYCTU
Sequence: MSVVAVTIFVAAYVLIASDRVNKTMVALTGAAAVVVLPVITSHDIFYSHDTGIDWDVIFLLVGMMIIVGVLRQTGVFEYTAIWAAKRARGSPLRIMILLVLVSALASALLDNVTTVLLIAPVTLLVCDRLNINTTSFLMAEVFASNIGGAATLVGDPPNIIVASRAGLTFNDFMLHLTPLVVIVLIALIAVLPRLFGSITVEADRIADVMALDEGEAIRDRGLLVKCGAVLVLVFAAFVAHPVLHIQPSLVALLGAGMLIVVSGLTRSEYLSSVEWDTLLFFAGLFIMVGALVKTGVVNDLARAATQLTGGNIVATAFLILGVSAPISGIIDNIPYVATMTPLVAELVAVMGGQPSTDTPWWALALGADFGGNLTAIGASANVVMLGIARRAGAPISFWEFTRKGAVVTAVSIALAAIYLWLRYFVLLH
What are the official names of this protein?
Uncharacterized transporter Rv2684.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2990_SULIN
Sequence: MKIKDAVNMIRWEYREKIDDYVIIIIDRLTENGLKEISFSELDAVDNNYLYLKSEENTVIPLHRVLMIKRKSDNALIWKR
What are the official names of this protein?
UPF0248 protein YN1551_2990.
What is the protein family that this protein belongs to?
Belongs to the UPF0248 family.
Protein: MUTL_STAAT
Sequence: MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSKLDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYIKSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPEHSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSKIQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQNTENNQEKTFSSEESNSKPFMEENQNDEIVIKEDSYNPFVTKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNDGTTVQNYENKASDDYYDVNDIKGTKSKDPKRRIPYMEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIMLEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREAEDPFTCPHGRPIIINFSKYELEKLFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RL6_PROMA
Sequence: MSRIGKKPIPVPEKVAVTLDGLLVTVKGPKGELTRTLPEGVTIDQTDGLIIVSADSEKRKSRERHGLSRTLVANMIEGVNNGYSKQLEIVGVGSRAQVKGKTLVVSAGYSHPVEVIPPEGITFKVENNTNVLVSGIDKELVGNEAAKIRAIRPPEPYKGKGIKYLGERILRKAGKSGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL28_STRPS
Sequence: MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKPKKVWASARALKSGKVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DPRA_MYCTU
Sequence: MIDPTARAWAYLSRVAEPPCAQLAALVRCVGPVEAADRVRRGQVGNELAQHTGARREIDRAADDLELLMRRGGRLITPDDDEWPVLAFAAFSGAGARARPCGHSPLVLWALGPARLDEVAPRAAAVVGTRAATAYGEHVAADLAAGLAERDVAVVSGGAYGIDGAAHRAALDSEGITVAVLAGGFDIPYPAGHSALLHRIAQHGVLFTEYPPGVRPARHRFLTRNRLVAAVARAAVVVEAGLRSGAANTAAWARALGRVVAAVPGPVTSSASAGCHTLLRHGAELVTRADDIVEFVGHIGELAGDEPRPGAALDVLSEAERQVYEALPGRGAATIDEIAVGSGLLPAQVLGPLAILEVAGLAECRDGRWRILRAGAGQAAAKGAAARLV
What is the function of this protein?
May help load RecA onto ssDNA (By similarity).
What are the official names of this protein?
Putative DNA processing protein DprA.
What is the protein family that this protein belongs to?
Belongs to the DprA/Smf family.