PharMolix/UniProtQA huggingface dataset:
Protein: G6PI_ROSDO
Sequence: MMSIWDALREKQAQVSDRSILSLFDDPGRAQEYSAKTGDLFFDFSKTNIDDEALNLLSGLLDASGMAQKRTAMFSGQPINDTEGRAVLHTALRNLDGGPVLVNGTDVMPGVLATLERMRVFAQGVRDSDVTDVVNIGIGGSDLGPAMAVAALSPYHDGPRCHFVSNVDGAHIADTLRGLDAKKTLVIVASKTFTTIETMTNARTARAWMTEHGGDPKAQFAALSTADDLTAAFGIPPERVFGFEDWVGGRYSVWGPIGLSLMIAIGPRAFDAFLRGGQAMDRHFQAADWRENLPVLLALVGVWHAQVCGCSSRAVLPYDQRLAKLPDYLQQLEMESNGKSVQIGGADVTVDSGPIVWGAAGTNGQHAFYQLIHQGTRVVPCEFLVAAEGHEPELAHHHNLLVANCLAQSEALMRGRSIEDARAKMVQAGFTGQELERQARHRVFAGNRPSVTLAYPKLDPFMLGQIIALYEHRVFVEGVILGINSYDQWGVELGKELATSLQPIVDGEAPADGKDGSTAQLVGYVIANRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTR3_YEAST
Sequence: MHSHRQKWGRQTDIARVLDDIEHDLYLPQRLSLDGATGTDESHVQYGIVKDCSVLTCGCCISESLFNDLCRETSNKQTACPICQRENVRLLSAIKPLRDLARQIDFFRSTTGQGESESDELPAIVKTSPSSSSLSLTPSRSSSTAGLEADNKTLSDPTVKEKSSLLELFHIVASKMHNANTEVGSDHPLTTGTTRDQEEHTTKENYSSSLLEPNYDDHANWKILDNASNTRTVPIDNNFSLMSTDVTIPSTANYQTNSAHDLDEEKEYFFANCFPMYRKKFQFNTHPKFLGTKSKLFINQSISPDCTKFALITEHKWEIYSINPKDNSPQLVSCGKSSGEYGPNFNQLTEQSSSSLSTTSQASKKKKKNWSQRFCKLSNDFLIISGSQNILNVHDIHQNGKLIYTYVSRFPIRCIDIDPRSQIIAYGITGKDRHTGAEQALVVIQQITRNKVTLEPEFPPPITITLPYRDPINTIQLSHDAKYLTCSTALESRFLIISLQKINEPRLIMKSVRSIDTSLESEGITDTKLFPGNPNLMCITSTAFNSSPLVINTKITQINGVRTVAQPSMLIRVDEIGCKIHKCEISPRNDAIAFLDRNGSVYIMCAPTMMDNNEKRRTILVETVANAYRAYESATLRFNPEGNKLYILDRKGTFFVEDFAYGLPQSREITKCKQIFHK
What is the function of this protein?
Component of the SPS-sensor system, which regulates the expression of several amino acid-metabolizing enzymes and amino acid- and peptide-permeases in response to extracellular amino acid levels by controlling the activity of two transcription factors, STP1 and STP2.
What are the official names of this protein?
SPS-sensor component PTR3, Peptide transport protein 3.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNFB_ALIF1
Sequence: MSSILIAVIAIAALALVFGLILGFASIKFKVESDPIVEQIDAILPQTQCGQCGYPGCKPYAEAIANGDMINKCPPGGQATIEKLADLMGVDVPSSAHDEEKSIKKVAFIHEDMCIGCTKCIQACPVDAIVGGTKALHTVIESECTGCDLCVAPCPTDCIEMIPVKTTPDNWKWDLNTIPVVNISTDQPSKSSEL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: PTH1_CORJK
Sequence: MASPNKKQHTNSDTWLIVGLGNPGDKYANTRHNVGRMVIGELLDRQVPAASLNTHKKTNTDIAEVKIAGRKVVLAQPRTFMNVSGGPVQQLAAFFKIPAENIIVAYDDLEGDPGAVKLRQSGGDKGHNGLKSITKSLGTKDYWRLSCGIGRPPGRMDPAAYVLKPFPKSEAAEVAIMCADAADEVERTLGVGN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase 1, PTH 1.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_STRPY
Sequence: RIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQEYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFNKSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGNLLRLHPLVCEAGNADFDGQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDAGREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDSQRHKIMVTTVGKILFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDGLDINVPFKKKNLGNIIAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVEEINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPFVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHSARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEVRLQGRYTRKSVKHPETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAVITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEGSIQPKRLLEVRDTLSVETYLLAEVQK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ASIP_GORGO
Sequence: MDVTRLLLATLLVFLCFFTANSHLPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKKSKQIGRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRNSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_CUPNH
Sequence: MQLNPSEISELIKSRISGLGAEAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTFGLALNLERDSVGAVVLGEYEHISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGPINAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIGRGQRELIIGDRQTGKTAVAVDAIINQKGKGVFCVYVAVGQKASTIANVVRKLEEHGAMEYTVVVAAAASDSAAMQYLAPYAGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEKFTNGAVKGKTGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKNLSGGIRTDLAQYRELAAFAQFASDLDDATRKQLERGRRVTELLKQPQYQPLQVWQLAASLFAANNGFLDNVEVKDILPFEKGLHDHLKTKYADLINRIEETKQLSKEDEAALRAAVEDFKKSAAF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLMH_EXISA
Sequence: MNISIITVGKLKEKYLKQGIAEYTKRLSAYAKVQEIEVSDEKAPEHLSEADMLLVKQKEGERILAKISPDTHVIALAIKGKQRTSEEFARELDQLATYGKSKIAFVIGGSLGLSDDVMKRADDTISFSKMTFPHQLMKLVLCEQIYRAYRINRNEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_ACIB3
Sequence: MSQTLQAAYAAKRKARRFAVQGIYEWQMSHNPVHEIEARTRAENAMHKVDLNYYHELLTQVIAQHEDLDALLIPVLDREIDALDGVELATLRLGAYELRDHLEIPYRVVLDEAIELAKHFGGADSHKYINGVLDRLSSTLRSAEKQQAK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ECFT_LACP3
Sequence: MDKLLLGRYIPGDSWVHRLDPRTKLIASFYYIGIVFLANNWQTYLMMFVATLFMIWLSGIKIGFFLKGVRPLIWLILFTVVLQVLFVRGGTVYWHWGWLWITEFGLINGAFIFVRFVLIIFMSTLLTLSTQPLSLADAVESLLKPLRVIRVPVTELALVLQIALRFVPTLMDQTTKIMNAQRARGVDFGEGNIFQQMKAVVPLLIPLFVSSFTTADELATAMEARGYQGGDDRTKYRILRYHRRDWVAAGGMLVLTGLLLLLRA
What is the function of this protein?
Part of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates including 5-formyltetrahydrofolate and thiamine.  Expression of the complex plus FolT or ThiT in Lactococcus lactis subsp.  cremoris (strain NZ9000) allows 5-formyltetrahydrofolate or thiamine uptake respectively; 5-formyltetrahydrofolate or thiamine are not taken up in the absence of FolT/ThiT or the EcfA1A2T complex.  Deenergized L. lactis subsp.  cremoris (treated with 2-deoxyglucose) do not take up substrate.
What are the official names of this protein?
Energy-coupling factor transporter transmembrane protein EcfT, ECF transporter T component EcfT.
What is the protein family that this protein belongs to?
Belongs to the energy-coupling factor EcfT family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y651_METJA
Sequence: MKKIYIILLILFVILISLIGASILLVMSLSGENVDLFGGEKIAKVYLCNEIYFDYNQGDGIFPQQKKDARYYINLLDDLEKDDSVKGVLLVVNSPGGEVIASEKLARKVEELAKKKPVVVYVEGLDASGAYMVSAPADYIVAEKHSIVGSIGVRMDLMHYYGLMKKLGINVTTIKAGKYKDIGSPFRPMTKEEKEYLQKMINETYMDFVKWVAEHRHLSINYTLKIADGKIYSGEDAKKVGLVDEVGTEEDALKKLEQLANVSNPEIVEYGLEENKGLFGLTYYLGYGIGKGIGEVLYGMEKINGRVELLS
What are the official names of this protein?
Putative protease MJ0651.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
Protein: SYD_RUMCH
Sequence: MGESIHGLERSHKCTELSSSNIGEKVTVMGWVQKQRNLGSLVFIDLRDRTGIVQLVFTDKDGEMFDKAKTIRSEYVIATVGTVAARSAEAVNKKMATGEIEIIASELRILSSSETPPMYIEENSDVNEQTRLKYRFLDLRRPDMQRNLILRHRVAKVARDYYDQNGFLEIETPILIKSTPEGARDYLVPSRVHPGKFFALPQSPQLYKQLLMVSGYDRYFQIAKCFRDEDLRADRQPEFTQIDIEMSFVNVDDVLEVNEGFVKKAFKEALGVDVETPFTRMPYAEAMERFGSDKPDIRFGMELVNMSDLVANCGFKVFTDAVAMGGSVRAINAKGCAKFSRKEIDALVDLVKTYKAKGMAWISISQENEIKSSFAKFMSEDEMKAILNRAQAEAGDLICFVADKNNVVFDALGQLRLEIARKLDILNPDEFKFLWVTEFPLFEYDEEDQRWAAKHHPFTSPMDEDLQYLDTDPGRVRAKAYDMVLNGVELGGGSIRIHIQELQAKMFKMLGFTEEDANRKFGFLLEAFKYGTPPHGGMAFGLDRLVMLMAKRNSIRDVIAFPKVQNASCPMSNAPDVVDETQIEELHISIAKE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HA1Z_MOUSE
Sequence: WLHRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWEPPPSTDSYMVIVAVLGVLGAMAIIGAVVAFVMKRRRNTGGKGGDYALAPGSQSSEMSLRDCKGDTLGSDWGGAMWT
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
H-2 class I histocompatibility antigen, alpha chain, Clone PH-2D-2.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CLPP_BURTA
Sequence: MASQAPRDFEAQALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSPGGSVSAGMAIYDTMQFVKPDVSTLCMGLAASMGAFLLASGAKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLKDRLNHLLAHHTGQDVERIARDTDRDNFMSSEDAKAYGLIDHVSTKRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCA2_ASHGO
Sequence: MIASRYVASELESVTRKLELQLYERAAISEVLEQTSTDLELAKANEVLQTIKEEADACVAAINGGQKFYTIKYDQILSGLESLSGGQWSVGSPLEPLIRDGISDYLHILLYYALLSKNLAKLPQLLLDQEYYGHVSRCSWFMRLFYGLQIMPVKLIEFFRGHALQELPSKLRQTLRIHNFQLVGLPTQRAWQWTKLPIAMVDTDIIQKTASLDSQLDINVKKFGKLLREFPRQKSDRLEVLSDFLDLKPGSSEFAVVRAVQKWNVDSCAPQPNWIVRYWPTILIALAGGPAGIAAIWNARNDIAAFIKHNLFEFARDLVKNWLVEPLRNIWSTVHHDPTSSIAIMSQGTLDTEINSLQRMLIDFLKEHEYANTVDTSVLMKEIEQGNLTQFMEIYEAQLRKPIRNLVTGDLIRSLLIQIQKGKVDGSLAIHGIDKLLQSQQLVFGIVSISPALLILYVLCNSLTKLVKYGTVWSKGAKYRRSVSVSLNNVERLLNSPIEEFDGDKGNWNLGLLTLEMANLREYGAKLVPHSRTAEWCRDIDEMASSSALSTTGKLNVINRIYHVYGKYF
What is the function of this protein?
Involved in the mitochondrial expression of subunits 6 and 8 of the F0-F1 ATP synthase.
What are the official names of this protein?
Nuclear control of ATPase protein 2.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SMAL1_MOUSE
Sequence: MSLPLTEEQRKKIEENRQKALARRAEKLSEQPQSAASGSSAAGPSQSKQGSLLNLLAEPSKPVGHASIFKQQNLSNSFPTDQRPHSSRCSQPSPAEETTGLWKTQGEMSTACPKPNPSPPGASNQPLLGYKSSEGQPQATWDTGASSSGPFPRDPELEAKAARPSTSRQSISDSFYVLGGKTPRTEGRPPNILQTTPQNTGFLRGACIKTGDRFRVKIGYNQELIAVFKSLPSRHYDSFTKTWDFSMSDYRALMKAVERLSTVSLKPLDEAGGSVGGQTSLPSAPSLTFVTGKCMLISRVRFEVDIGYSEAVIGLFKQMESRSYDIKTRKWSFLLEEHNKLIARSRELKQVQLDPLPKTVTLAFASQLEKTSPKLKADVPEADLSGVDAKLVSSLMPFQREGVSFAISKRGRLLLADDMGLGKTVQAICIAAFYRKEWPLLVVVPSSVRFTWEQAFLRWLPSLSPENINVVVTGKGRLTAGLVNIVSFDLLCKLERQLKTPFKVVIIDESHFLKNIKTARCRAAVPILKVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFGLRYCDAKRLPWGWDYSGSSNLGELKLLLEEAIMLRRLKSDVLSQLPAKQRKMVVVNPGRISSRAKAALDAAAKEMTKDKTKQQQKEALLVFFNRTAEAKIPCVVEYILDLLDSGREKFLVFAHHKVILDAVAKELERKNVQHIRIDGSTPSADREAQCQRFQLSKGHTVALLSITAANMGLTFSTADLVVFAELFWNPGVLIQAEDRVHRIGQTNSVSIHYLVAKGTADDYLWPLIQEKIKVLGEAGLSETNFSEMTEATDYVHKDPKQKTIYDLFQQSFEDDGNDMEFLEAAESFELGSTSGTSGNISQDLGDLLDEDEGSPPKKSRFEFFDNWDSFSSPF
What is the function of this protein?
ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA.  Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA).  Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA.  May play an important role in DNA damage response by acting at stalled replication forks (By similarity).
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, HepA-related protein, mharp, Sucrose nonfermenting protein 2-like 1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Recruited to damaged DNA regions.
Protein: AGRE1_RAT
Sequence: MWGFWLLLFWGFSGTHRWGMTTLAILGQRLNGVNECQDTTTCPAYATCTDTTESYYCTCKQGFLPSNGQTNFQGPGVECQDVNECLRSDSPCGSNSVCTNIPGRARCSCLSGFSSSAGGSWILGSPGHFLCTDVDECLTIGICPKNSNCSNSVGSYSCTCQSGFVSNGSTCEDEDECVTRNACPEHATCHNTLGSYYCTCNEGLEFSGGGPMFQGLEESCEDVDECSRNSTLCGPSFICINTLGSYSCSCPAGFSLSTFQIPGHPADGNCTDIDECDDICPSNSSCTNTLGSYFCTCHPGFASSNGQLNFTDQEVTCEDIDECTQDPFRCGRNSSCTNVPGSYNCSCLPDFRMDPGGSQAHGNFTCKRIPFKCKEDLIPKSEQIEQCQAGQGRNLDYTSFCTFVNATFTILDNTCENKSAPVSLQSAATSVSLMLEQASTWFEFSREETSTLGTILLETVESTMLAALLTPSGNASQTIRTEYLEIESKVINEECNEENVSINLKARGDKMDVGCFIIKESESTGTPGVAFVSFAHMDSVLDERFFEDGQASWKLRMNSHVVGGTVTGERKEDFSKPIVYTLQHIQPKQKSERSICVSWNTDVEDGRWTPSGCETVEASETHTVCSCNRMTNLAIIMASGELTMEFSLYIISYVGTVISLVCLALAIATFLLFRAVQNHNTYLHLHLCVCLFLAKILFLTGIDKTDNQTACAIIAGFLHYLFLACFFWMLVEAVMLFLMVRNLKVVNYFSSRNIKMLHLCAFGYGLPVVVVIISATVHPWGYGMHNRCWLNTETGFIWSFLGPVCMIITINSALLAWTLWVLRQKLCSVNSEVSKLKDTRLLTFKAIAQIFILGCSWVLGIFQIGPLASIMAYLFTTINSLQGAFIFLIHCLLNRQVRDEYRKLLTRKTDLSSHSQTSGILLSSMPSTSKTG
What is the function of this protein?
Orphan receptor involved in cell adhesion and probably in cell-cell interactions involved specifically cells of the immune system.  May play a role in regulatory T-cells (Treg) development.
What are the official names of this protein?
Adhesion G protein-coupled receptor E2, EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, EMR1 hormone receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCL3_HUMLU
Sequence: MGMVGRDIDDLPKNAANYTALTPLWFLERAATVHPTRTSVIHGSRHYTWLQTYHRCRQFASALNNHSIGLGSTVAVIAPNVPALYEAHFAVPMAGAVVNCVNIRLNASTIAFLLGHSSAAAVMVDQEFFSLAEEALKILAQESKSHYKPPLLVVIGDESCDPKTLEYALKTGAIEYEKFLEGGDPEFDWKPPEDEWQSISLGYTSGTTASPKGVVLSHRGAYLMSLSASVVWGINEGAIYLWTLPMFHCNGWCYTWGMAAFCGTNICLRQVTAKGVYSAIAKYGVTHFCAAPVVLNTIVNAPPEEAIIPLPHLVHVMTAGAAPPPSVLFAMSEKGFKVAHTYGLSETYGPSTICAWKPEWDSLPPIKQARLNARQGVRYIALEGLDVVDTKTMKPVPADGTTMGEIVMRGNAVMKGYLKNPKANEESFADGWFHSGDLAVKHPDGYIEIKDRSKDIIISGGENISSLEVENTLYLHPAVLEVSVVARPDERWGESPCAFVTLKPNIDKSNEQVLAEDIIKFCKSKMPAYWVPKSVVFGPLPKTATGKIQKHVLRAKAKEMGALKKSNL
What is the function of this protein?
Involved in the biosynthesis of prenylated phenolics natural products which contribute to the bitter taste of beer and display broad biological activities (Probable).  Catalyzes the ligation of CoA on propanoate to produce propanoyl-CoA (PubMed:23300257).  Can also use 2-methylpropanoate (isobutyric acid), acetate, butanoate, isovalerate, pentanoate, hexanoate, 2-methylbutanoate, 2-methylpentanoate, 3-methylpentanoate and 4-methylpentanoate as substrates with a lower efficiency (PubMed:23300257).  Triggers the formation of very short chain acyl-CoAs from the corresponding fatty acids, including acetic acid, propanoic acid, butyric acid and its isomer (PubMed:23300257).
What are the official names of this protein?
Acetate--CoA ligase CCL3, HlCCL3, 2-methylbutanoate--CoA ligase CCL4, 2-methylpropanoate--CoA ligase CCL4, Butanoate--CoA ligase CCL3, Hexanoate--CoA ligase CCL3, Isovalerate--CoA ligase CCL3, Pentanoate--CoA ligase CCL3, Propionate--CoA ligase CCL3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MDHP_PEA
Sequence: MALTQLNSTCSKPQLHSSSQLSFLSRTRTRTLPRHYHSTFAPLHRTQHARISCSVAPNQVQVPAAQTQDPKGKPDCYGVFCLTYDLKAEEETKSWKKLINIAVSGAAGMISNHLLFKLASGEVFGPDQPIALKLLGSERSIQALEGVAMELEDSLFPLLREVVISIDPYEVFQDAEWALLIGAKPRGPGVERAALLDINGQIFAEQGKALNAVASRNAKVIVVGNPCNTNALICLKNAPNIPAKNFHALTRLDENRAKCQLALKAGVFYDKVSNMTIWGNHSTTQVPDFLNARIDGLPVKEVIKDNKWLEEEFTEKVQKRGGVLIQKWGRSSAASTSVSIVDAIRSLITPTPEGDWFSSGVYTNGNPYGIAEDIVFSMPCRSKGDGDYELVNDVIFDDYLRQKLAKTEAELLAEKKCVAHLTGEGIAVCDLPGDTMLPGEM
What is the function of this protein?
The chloroplastic, NADP-dependent form is essential for the photosynthesis C4 cycle, which allows plants to circumvent the problem of photorespiration.  In C4 plants, NADP-MDH activity acts to convert oxaloacetate to malate in chloroplasts of mesophyll cells for transport to the bundle sheath cells.
What are the official names of this protein?
Malate dehydrogenase [NADP], chloroplastic, NADP-MDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: URE1_TRIEI
Sequence: MSYRMNRRTYAETFGPTVGDRVRLADTELFIQVEKDYTTYGDEVKFGGGKVIRDGMGQSPISREGGAVDLVITNALILDWWGVVKADIGIKDGKIHKIGKAGNPYIQDRVDIIIGPSTEIIAGEGHIITAGGIDSHIHFICPQQIEIAIASGITTMIGGGTGPATGTNATTCTPGQWNIWMMLQAADAFPMNLGFLGKGNSAKPEGLIEQIKAGAMGLKLHEDWGTTPAAIDTCLSVADEYDVQVAIHTDTLNEAGFVENTIAAFKDRVIHTYHTEGAGGGHAPDIIKVCALKNVLPSSTNPTRPFTVNTLEEHLDMLMVCHHLDKNIPEDVAFAESRIRKETIAAEDILHDLGAFSAIASDSQAMGRVGEVIIRTWQTAHKMKVQRGILASEKKEVADNFRAKRYIAKYTINPAIMHGIADYVGSIEAGKLADICLWKPAMFGVKPEIVIKGGAIAWAQMGDPNASIPTPQPVYMRPMFGSFGGATSSTSLTFVSQEALDAEIPKKINLKTPAVAVSNTRNISKADMKLNEATPKIEVNPETYEVRADGELLTCEPAYVLPMTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMG_MYCTO
Sequence: MSAWRAPEVGSRLGRRVLWCLLWLLAGVALGYVAWRLFGHTPYRIDIDIYQMGARAWLDGRPLYGGGVLFHTPIGLNLPFTYPPLAAVLFSPFAWLQMPAASVAITVLTLVLLIASTAIVLTGLDAWPTSRLVPAPARLRRLWLAVLIVAPATIWLEPISSNFAFGQINVVLMTLVIVDCFPRRTPWPRGLMLGLGIALKLTPAVFLLYFLLRRDGRAALTALASFAVATLLGFVLAWRDSWEYWTHTLHHTDRIGAAALNTDQNIAGALARLTIGDDERFALWVAGSLLVLAATIWAMRRVLRAGEPTLAVICVALFGLVVSPVSWSHHWVWMLPAVLVIGLLGWRRRNVALAMLSLAGVVLMRWTPIDLLPQHRETTAVWWRQLAGMSYVWWALAVIVVAGLTVTARMTPQRSLTRGLTPAPTAS
What is the function of this protein?
Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature lipoarabinomannan (LAM).
What are the official names of this protein?
Polyprenol-phosphate-mannose-dependent alpha-(1-2)-phosphatidylinositol mannoside mannosyltransferase, Alpha-D-mannose-alpha-(1-2)-mannosyltransferase, Alpha-mannosyltransferase, Alpha-ManT, PPM-dependent mannosyltransferase, Polyprenol-phosphate-mannose alpha-mannosyltransferase, PPM alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 87 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TGT_RICCK
Sequence: MSKFSFNIHQMHKKARSGVITTAHGEIRTPAFMPVGTRGTIKAMLSESVAETGADILLGNTYHLMLQPSSERIARLGGLHKFMNWHKPILTDSGGFQVMSLSKLCKITEEGVSFSSHINGDKYMLTPERSTEIQYLLGSTITMAFDECTAYPATFEEAKTSVQLTTRWADRSRKAFVKREGYAQFGIIQGSVYQELREQSAKDLVKLDFEGYAIGGLAVGEGQELMFKVLDYTPNFLPQNKPCYLMGVGKPADIIGAVSRGIDMFDCVIPTRSGRNGQAFTKYGTVNIRNSKYADDDEPLEYDCLCPACKNYSKAYLHYLVKIGEILGSMLMTWHNLTYFQNLMSRIRTYIKAGQDFDFIT
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ASSY_STRMU
Sequence: MSKEKVILAYSGGLDTSVAITWLKKDYDVVAVCMDVGEGKDLEFIHDKALKVGAIESYVLDIKDEFAEEYVLPALQAHAYYEQKYPLVSALSRPVISKKLVEIAHQTGATTIAHGCTGKGNDQVRFEVAIAALDPKLKVIAPVREWKWSREEEINYAKENGVPVPADLDNPYSVDQNLWGRANECGVLENPWNQAPEEAFGITNSVEEAPDKAEYVDITFKEGKPVALDGQEMKLADLIQKLNVLAGKHGVGRIDHVENRLVGIKSREIYECPGAVTLLTAHKEIEDITLVREVSHFKPILENELSNLIYNALWFNPATQAILAYITETQKEVNGTAKVKLYKGSARVVARKSPHSLYDENLATYTSADSFDQDAAVGFIKLWGLPTQVNSQVNNK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.