PharMolix/UniProtQA huggingface dataset:
Protein: RPE65_CYNPY
Sequence: MSSKVEHPAGGYKKLFETVEELASPITAHVTGRIPVWLTGSLLRCGPGLFEVGSEQFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDTYVRAMTEKRIVITEFGTFAFPDPCKNIFSRFLSYFQGLEVTDNTLVNVYPVGEDYYACTETNYITKVNPETLETIKKVDLCNYVSINGVTAHPLIENDGTVYNIGNCFGKHFSFAYNIVKIPPLQEDKEDPINKAKVVVQFPCSERFKPSYVHSFGLTPNYIVFVEQPVKINLFKFLSSWSIWGANYMDCFESHETMGVWMHVAEKLTGEYLNIKYRTSAFNLFHHINTYEDHGFLIVDLCCWKGFEFIYNYLYLANMRENWEEVKRNAEKAPQPEVRRYVLPLDIHKVDTGKNLVNLPYTTATAILRSDETIWLEPEVLFSGPRLAFEFPQINYKKFGGKDYTFAYGLGLNHFVPDRLSKLNVKTKEIWVWQEPDSYPSEPIFVSQPDAMEEDDGVVLSVIVNPGPGQKPAFLLILNAKDMSEIARAEVDINIPVTFHGMYKKA
What is the function of this protein?
Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins.  Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore.  Essential for the production of 11-cis retinal for both rod and cone photoreceptors.  Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid.  The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester.  The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol.  The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT.
What are the official names of this protein?
Retinoid isomerohydrolase, All-trans-retinyl-palmitate hydrolase, Lutein isomerase, Meso-zeaxanthin isomerase, Retinal pigment epithelium-specific 65 kDa protein, Retinol isomerase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ARYA_MANSE
Sequence: MKTVVILAGLVALALSSAVPPPKYQHHYKTSPVDAIFVEKQKKVFSLFKNVNQLDYEAEYYKIGKDYDVEANIDNYSNKKVVEDFLLLYRTGFMPKGFEFSIFYERMREEAIALFELFYYAKDFETFYKTASFARVHVNEGMFLYAYYIAVIQRMDTNGLVLPAPYEVYPQYFTNMEVLFKVDRIKMQDGFLNKDLAAYYGMYHENDNYVFYANYSNSLSYPNEEERIAYFYEDIGLNSYYYYFHMHLPFWWNSEKYGPFKERRGEIYYYFYQQLIARYYLERLTNGLGEIPEFSWYSPVKTGYYPMLYGSYYPFAQRPNYYDIHNDKNYEQIRFLDMFEMTFLQYLQKGHFKAFDKEINFHDVKAVNFVGNYWQANADLYNEEVTKLYQRSYEINARHVLGAAPKPFNKYSFIPSALDFYQTSLRDPVFYQLYDRIINYINEFKQYLQPYNQNDLHFVGVKISDVKVDKLATYFEYYDFDVSNSVFVSKKDIKNFPYGYKVRQPRLNHKPFSVSIGVKSDVAVDAVFKIFLGPKYDSNGFPIPLAKNWNKFYELDWFVHKVMPGQNHIVRQSSDFLFFKEDSLPMSEIYKLLDEGKIPSDMSNSSDTLPQRLMLPRGTKDGYPFQLFVFVYPYQAVPKEMEPFKSIVPDSKPFGYPFDRPVHPEYFKQPNMHFEDVHVYHEGEQFPYKFNVPFYVPQKVEV
What is the function of this protein?
Arylphorin is a larval storage protein (LSP) which may serve as a storage protein used primarily as a source of aromatic amino acids for protein synthesis during metamorphosis.  It is a constituent of the sclerotizing system of the cuticle, and serves as a carrier for ecdysteroid hormone.
What are the official names of this protein?
Arylphorin subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the hemocyanin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: LCFA_YERPE
Sequence: MEKVWLKRYPADVPAEIDPDRYSSLIEMFENAALRYADQPAFINMGEVMTFRKLEERSRAFAAYLQQGLGLQKGDRVALMMPNLLQYPIALFGVLRAGMIVVNVNPLYTPRELEHQLSDSGAVAIVIVSNFAHTLEKVVFKTQVRHVILTRMGDQLSAAKGTLVNFVVKYIKRLVPKYYLPDAISFRTVLQKGRRMQYVKPDVINTDTAFLQYTGGTTGVAKGAILTHRNMQSNLEQAKAAYAPLLQPGRDLVVTALPLYHIFALTVNCLLFIELGGRSLLITNPRDIPGMVKELSRYPFTAITGVNTLFNALLNNEEFTHLDFSTLRLSVGGGMPVQKAVAEKWETLTGKHLLEGYGLTECSPLVTGNPYDLKHYSGSIGLPVPSTDVRLRDDDGNDVELGKPGELWVRGPQVMLGYWQRPDATDDVLKDGWLATGDIATMDEDGFLRIVDRKKDMILVSGFNVYPNEIEEVVALHAKVLESAVIGVPNEVSGEAVKVFVVKNDASLTPEELLTHCRRYLTGYKVPKIVEFRDELPKSNVGKILRRELRDEEVKVGTTDAA
What is the function of this protein?
Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids.
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase, Long-chain acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Partially membrane-associated.
Protein: ADDA_ANOFW
Sequence: MIPPKPRESQWTDEQWQAIYATGQHTLVAAAAGSGKTAVLVERIIQKILHKERPIDVDRLLVVTFTNAAAAEMRQRIGEALERALEKEPHSLHLRRQLSLLQKASISTIHSFCLDVIRKYYYVIGIDPVFRIADEGEMALLKEEVLETLFEQYYAENDEPFLTVVDRYTSDRTDADLQTLILRLYEFSRSHPNPSGWLQQIVHMYDVEEGARIDDLPYAHYLFQAVDLALEAAEYRLAQALQKTKEPGGPDYLYDTLASDEQVIAKLKEARHESWQQLHEAMKNVSFATAKRKPKDGAYDEQLVEDVKKLRDQVKKEISSITEELFSFQPVTYVRHLHEMKPIVTTIVQMVQRFAHLLQAKKDEKGIVDFSDLEHYCLRILRAPSLEHELKPSEAALYYRAQFAEVLVDEYQDTNMVQESILRLVSNDDEATGNMFMVGDVKQSIYGFRLAEPSLFLQKYNRFTKDGDGGLRIDLAKNFRSRKEILDGTNFIFRQLMTETVGDMRYDDDAALRFGAQDYPDKQIPVECVWINEAKEESDEEEQEDVTAVQLEARWIAKKIKQLLAEPFFVYDRRLKGERRLMYRDIVILCRSMSSASAMLEEFRKQNVPVYAELSSGYFSATEVSIMLSLLKVIDNPYQDIPLAAVLRSPIVGLDEEALARIRLAKKDGAFYEALCAFVQEPHDDELHEKMKRWLASLSEWRTAARQKPLADLIWQLYRETNFYDYVGGMPGGKQRQANLRALYDRAKQYEQTSFRGIFRFLRFIERLKEREDDFGAARSLTEQEDVVRMMTIHKSKGLEFPVVFLAGAAKSFNMQDLRSDYVLDKDFGLGMRFVHPTWRASYPTVAQLAIKKKMKWQLLAEEMRILYVALTRAKEKLYIVCTAKDMEAKKKKWQEVAYTSTWELPAYVIEKAKSYADWIGYALARHQQGICSSATVLHDPSLWDIHIVPAHELEQEDAQANEHRDIVEAIQQLQPVAIKSEYEEEVNRRLFWTYTHAPATVLRAKQSVSELKRQRDIYGGHAEQPFRKELVERPRFLQAKMMTPAERGTMMHLVMQHVDVTKEVTVDAVREQIARMVNGEWLTEEQATVIDVESIVAFFNTPIGKRMQRATRLEREVPFYLAHEMEGETVVVQGVIDCVFEDEHGLVLIDYKTDRVSWMNDPKQQLKRRYKGQLALYREAIEAIWKREVTETYVYAFDGALLVPMEVD
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: TRMY_METM7
Sequence: MKEFIIKANKAVTNGEINLKDLPGSSGRLDLLCRCVNSAFFLSHDMRRDTIFYSVNYGDPNPPVTLKFVGSELKRVSPDERSIALFIKKALEKDATELWKESTSGIYSSKREFRDIILEKKNEGKRIFYLHLNGKPLEDFEFKDDEDFLFVLGDHIGIGDEDEEFLEEIGAEKISLSPLELHADHCIILVHNILDRLK
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIW_ALKCK
Sequence: MQLETSYLGTVKYKQEDIIVFQGGLPGFPEETEFILLPFNEQPPFYILQSVRTKEIGFVCINPFLFWPDYEVELADSVVRQLSAESEQDVAIFVFLTIQQPFSKSTANLRAPIAVHAKKRFAKQLMLDGERYSLKAPIHTAGKGGR
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUSF_ECO57
Sequence: MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKGFDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSGIKTGDKVAFNFVQQGNLSLLQDIKVSQ
What is the function of this protein?
Part of a cation efflux system that mediates resistance to copper and silver.  Binds one copper per polypeptide (By similarity).
What are the official names of this protein?
Cation efflux system protein CusF.
What are the subcellular locations of this protein?
Periplasm.
Protein: CH10_SHEPA
Sequence: MNIRPLHDRVIVKRSEVESKSAGGIVLTGSAAEQSSRGEVLAVGNGRILENGNLMPLDVKVGDIVIFNEGYGVKKEKIDGEEVLILSESDLMAVVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXM_THUOB
Sequence: SNTSHQDFHSFYGTNLMIGG
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7B-liver, mitochondrial, Cytochrome c oxidase polypeptide VIIb-liver.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIb family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: WAC_BPT4
Sequence: MTDIVLNDLPFVDGPPAEGQSRISWIKNGEEILGADTQYGSEGSMNRPTVSVLRNVEVLDKNIGILKTSLETANSDIKTIQGILDVSGDIEALAQIGINKKDISDLKTLTSEHTEILNGTNNTVDSILADIGPFNAEANSVYRTIRNDLLWIKRELGQYTGQDINGLPVVGNPSSGMKHRIINNTDVITSQGIRLSELETKFIESDVGSLTIEVGNLREELGPKPPSFSQNVYSRLNEIDTKQTTVESDISAIKTSIGYPGNNSIITSVNTNTDNIASINLELNQSGGIKQRLTVIETSIGSDDIPSSIKGQIKDNTTSIESLNGIVGENTSSGLRANVSWLNQIVGTDSSGGQPSPPGSLLNRVSTIETSVSGLNNAVQNLQVEIGNNSAGIKGQVVALNTLVNGTNPNGSTVEERGLTNSIKANETNIASVTQEVNTAKGNISSLQGDVQALQEAGYIPEAPRDGQAYVRKDGEWVFLSTFLSPA
What is the function of this protein?
Chaperone involved in tail fiber assembly and retraction.  Acts as a chaperone helping to attach the long tail fibers to the virus during the assembly process.  During phage assembly, twelve fibritin molecules attach to the phage neck via gp13: six molecules forming the collar and six molecules forming the whiskers.
What are the official names of this protein?
Fibritin, Collar protein, Whisker antigen control protein.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the neck.
Protein: PYRB_ECODH
Sequence: MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: REX_HTL1F
Sequence: MPKTRRRPRRSQRKRPPTPWPTSQGLDRVFFSDTQSTCLETVYRATGAPSLGDYVRPVYIVTPYWPPVQSIRSPGTPSMDALSAQLYSSLSLDSPPSPPREPLRPSRSLPRRPPIQPPTFHPPSSRPCANTPPSETDTWNPPLGSTSQPCLFQTPASGPKTCTPSGEAPLSACTSTSFPPPSPGPSCPT
What is the function of this protein?
Rex escorts unspliced gag-pro-pol and singly spliced env mRNAs out of the nucleus of infected cells.  These mRNAs carry a recognition sequence called Rex responsive element (RxRE or XRE) located at the 3' region of the long terminal repeat (LTR).  This function is essential since most HTLV proteins are translated from unspliced or partially spliced pre-mRNAs that cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rex itself is translated from a fully spliced mRNA that probably readily exits the nucleus.  Rex's nuclear localization signal (NLS) binds directly to KPNB1/importin beta-1 without previous binding to KPNA1/importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rex to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rex from KPNB1 and allows Rex's binding to the RRE in viral pre-mRNAs.  Rex multimerizes on the RRE via cooperative assembly.  This multimerization is critical for its full biological activity, since it may shield the viral RNA from being spliced or down-regulated, and probably exposes Rex's nuclear export signal (NES) to the surface.  Rex can then form a complex with XPO1/CRM1, RANBP3 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rex/RRE/XPO1/RANBP3/RAN complex, so that Rex can return to the nucleus for a subsequent round of export (By similarity).
What are the official names of this protein?
Protein Rex, Rev homolog, Rex-1, p27Rex.
What is the protein family that this protein belongs to?
Belongs to the deltaretrovirus Rex protein family.
What are the subcellular locations of this protein?
[Isoform Rex]: Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm. SUBCELLULAR LOCATION: [Isoform p21Rex]: Host cytoplasm.
Protein: GLE1_MOUSE
Sequence: MPSDGRCWETLRALRNTSKGRLRYDREWLLRYEDVLEECMSLPKLSSYSGWVVDHILPNTSGHTQESAPSSDNSPSSGSASGLYQSSLLKSPVRSSPQSPSPSSPNGTQSTHESPFTEPIAPQSSRAIKVEGCIRMYELAHRMRGTEGLRQWQEEQERKVRALSEMASEQLKRFDELKELKLHKEFQDLQEVMEKSTREALGHQEKLKEEHRHRAKILNLKLREAEQQRVKQAEQEQLRKEEGQVRLRSLYSLQEEVLQLNQQLDASSQHKELLSVDLAAFQTRGNQLCGLISSIIRTTLESGYPTAENQAEAERALQEMRDLLSDLEQEITRASQVKKKHEEEAKVKRQESQVQQGPAPPTQTSAPSPSPVGAQNEDLQVKVQDSTMQWYQQLQDASAKCVLAFEDLTSSKDSQTKKIKMDLQKAATIPVSQISTIAGSKLKEIFDKIHSLLSGKPVQSGGRSVSVTLNPQGLDFVQYKLAEKFVKQGEEEVASHHEAAFPIAVVASGIWMLHPKVGDLILAHLHKKCPYSVPFYPAFKEGMALEDYQRMLGYQVTDSKVEQQDNFLKRMSGMIRLYAAIIQLQWPYGNRQEAHPHGLNHGWRWLAQVLNMEPLSDVTATLLFDFLEVCGNALMKQYQVQFWKMILLIKEDYFPRIEAITSSGQMGSFIRLKQFLEKCLQRREIPVPRGFLTTSFWRS
What is the function of this protein?
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm.  May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC) (By similarity).
What are the official names of this protein?
mRNA export factor GLE1, GLE1 RNA export mediator, GLE1-like protein, Nucleoporin GLE1.
What is the protein family that this protein belongs to?
Belongs to the GLE1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nuclear pore complex. Note=Shuttles between the nucleus and the cytoplasm. Shuttling is essential for its mRNA export function.
Protein: NRCAM_HUMAN
Sequence: MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSGFVSSEDVFETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNSFV
What is the function of this protein?
Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system.  Plays a role in neurite outgrowth in response to contactin binding.  Plays a role in mediating cell-cell contacts between Schwann cells and axons.  Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons.  Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons.  During development, nodes of Ranvier are formed by the fusion of two heminodes.  Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters.  Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.
What are the official names of this protein?
Neuronal cell adhesion molecule, Nr-CAM, Neuronal surface protein Bravo, hBravo, NgCAM-related cell adhesion molecule, Ng-CAM-related.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Secreted. Note=Detected at nodes of Ranvier.
Protein: KYNU1_PHANO
Sequence: MSQTTNSYDSFQDADLCSAAFAEKQDEKDKLTKLREDFYIPTKGDLINKKYGFQKSGNNAKGHENGKCIYFCGNSLGLQPTRTKEYINRYLDTWASKGVFGHFTDYEGGLPPWLHIDDAVKEQTSKIVGALPSEVVIMETLTANLHLLMSSFYRPTKDRWKIIIEGKAFPSDHYAALSQIAHHDLDPSALITIEPPSSSAPYLSNEHILSVISKHAATTALVLLPGIQFYSGQFFDIELITRHCRALGITVGWDLAHAVGNVPLKLHDWNVDFAAWCNYKYMSGGPGVIGGAFVHERHGTVGETAPTTTPDGTNGNPKTISDESLTYRPRLSGWWGNDKSSRFTMDNKFVPIPGASGYQLSNPSALDMTSVMASLDVFALTTMDALRERSIRLTGYLEARLLRYPGGEPPYTIITPTNPAERGAQLSVMLRPGMLDSVLHHLEKEGVVVDERKPDVLRIAPAPLYNTFRDVHDFIGIFHEACRKALVKPAEAPKHSEGVPKAIQTT
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase 1, Biosynthesis of nicotinic acid protein 5-1, L-kynurenine hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO145_CAEBR
Sequence: MEKILVTLSTGAASIAVLAVLFTIPSLYNTINEVHDEVLDGVSVFRVETDSAWTEMMDIQITVTPPTKPRVNPFNSIFRQKRQTFSGLPAWCQCEPTKPTCPPGPPGPPGQPGQPGTPGAPGPKGEDNTSTYAPITCAPVSQDCVKCPQGPAGPEGPAGPAGPAGPDGQPGAPGNAGNPGSDGQPGAPGDDGQPGAPGQDGQPGAPGQDGQRGSGAPGAPGAPGNAGPAGPAGQDGAPGQDGQPGPAGPAGQDGAPGNAGSDGQPGAPGGPGLPGNDAAYCACPHGEDSCDHLYRSCLPRCFGEVLDGVSVFRVETDSAWTEMMDIQVTVTPPTKPRVNPFNSVFRQKRQTFSGLPAWCQCEPTKPTCPPGPPGPPGQPGQPGTPGAPGPKGEDNTATYAPITCAPVSQDCVKCPQGPAGPTGPAGLAGPAGPDGQPGFPGQRGNDGFPGAPGAPGDNGQPGAPGQDGFPGQPGADGQRGSGAPGAPGAPGNAGPAGPAGQDGFPGQDGQPGPAGPAGQDGFPGNAGSDGQPGAPGGPGLPGNDAAYCACPPRSAVFLSRH
What is the function of this protein?
Nematode cuticles are composed largely of collagen-like proteins.  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (By similarity).
What are the official names of this protein?
Putative cuticle collagen 145.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
Protein: C10_VAR67
Sequence: MDIYNDKGLQTIKLFNNEFDCIRNDIRELFKHVTDSDSIQLPMEDNSDIIENIRKILYRRLKNVECVDIDSTITFMKYDPNDDNKRTCSNWVPLTNNYMEYCLVIYLETPICGGKIKLYHPTGNIKSDKDIMFAKTLDFKSKKVLTGRKTIAVLDISVSYNRSMTTIHYGDVDIDIHTDKNGKELCYCYITIDDHYLVNVETIGVIVNRSGKCLLVNNHLGIGIVKDKRISDSFGDVCMDTIFDFSEARELFSLTNDDNRNIAWDTDKLDDDTDIWTPVTEDDYKFLSRLVLYAKSQSDTVFDHYVLTGDTEPPTVFIFKVTRFYFNILK
What are the official names of this protein?
Protein C10.
What is the protein family that this protein belongs to?
Belongs to the poxviridae C4/C10 protein family.
Protein: ZEO1_YEAST
Sequence: MSEIQNKAETAAQDVQQKLEETKESLQNKGQEVKEQAEASIDNLKNEATPEAEQVKKEEQNIADGVEQKKTEAANKVEETKKQASAAVSEKKETKKEGGFLKKLNRKIASIFN
What is the function of this protein?
Acts antagonistically to MID2 in signaling cell wall stress to the PKC1-MPK1 cell integrity pathway.
What are the official names of this protein?
Protein ZEO1, Zeocin resistance protein 1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS11_ECO45
Sequence: MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: Y13K_NPVOP
Sequence: MGVRVAQPAAKQFVVLQQVEVLYGVVSQVALLHDAELLVVFDQLWQQFALAAHLFKHVAQVAAGHLALLELFCQLTNVVLVAAPRARLDQLRQLVLQAPVLLAAKRCEREHWLDQRRHL
What are the official names of this protein?
Uncharacterized 13.4 kDa protein in ubiquitin 3'region, Lambda 208.
Protein: PANB_AQUAE
Sequence: MAINLQTLFKKKREGKKITMVSTYDYWSAKLCDEVGIDCILVGDSLGTVVKGEGDTLSVTLEEIIYHTKCVMRGVKNAFVIADMPFMSYQVSMEKAVENCGRVIKETKAKAVKLEGGEEIAELVYKLTRIGIPVVGHVGFTPQHINVFGKPKVVGKKKEEEEKLRRDFRALEEAGAFMIVLESVPTHLAKELWKGSNSIVIGIGAGKYVDGQVLVFHDIVGLFEDFKPKFVRRYLEGAKLVKEALKNFKIDVEGGNFPSEEESYG
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_HELHP
Sequence: MKVSISHKNNFKGVSYQAQALLMSKSVFAKSPYAKLCKSFGFEGEGKFFLQEQALLLVCVEELGLDSIREAGASIARHFRTLPYKNVNVALNGKLDDSKAYALLLGALLGVYECVSYKTKTPPLHLKEIILLDEKNEVASESVLKKVHIVAQSVNEVREIINTIPQVATPKYLAKYAKELSKEVGNLECKILDEEALQKEKMGAFLAVNRASCNPPRLIHLSYKPKGAKKRIVLVGKGLTYDCGGLSLKPADFMVTMKADKSGGCAVMGIIKAIAQLGANIEVHSIIGAAENMIGGNAYKPDDVLYSREGKSIEVRNTDAEGRLVLVDCLSYAQDLKPDILIDFATLTGACVVALGEFTSGIMGHNDRLKAQFEKCALESGELMATLPFNRHLKKLIESKIADVCNVGSSRYGGAISAGLFLSEFIREEFKQKWLHIDIAGPAYVEKEWDINPSGASGAGVRAGIEFILAQGKA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.