PharMolix/UniProtQA huggingface dataset:
Protein: PRP22_YEAST
Sequence: MSDISKLIGAIVGSDDPVIIEFVLNIINKSGNLQEFIRNIQKLDAGISYEDSIKMYNAFLGKQEEEKVRNKVKSSPLSQKINQVLKDDVNLDDPVVTEFVLSILNKSKSITEFQEQLNLMQSGLDNETIFKIYQIASPPVMKEEVSVLPSTKIPAKIEAKIEEEVQKIESLDPSPVLHKVYEGKVRNITTFGCFVQIFGTRMKNCDGLVHISEMSDQRTLDPHDVVRQGQHIFVEVIKIQNNGKISLSMKNIDQHSGEIRKRNTESVEDRGRSNDAHTSRNMKNKIKRRALTSPERWEIRQLIASGAASIDDYPELKDEIPINTSYLTAKRDDGSIVNGNTEKVDSKLEEQQRDETDEIDVELNTDDGPKFLKDQQVKGAKKYEMPKITKVPRGFMNRSAINGSNAIRDHREEKLRKKREIEQQIRKQQSFDDPTKNKKDSRNEIQMLKNQLIVTEWEKNRMNESISYGKRTSLPISAQRQTLPVYAMRSELIQAVRDNQFLVIVGETGSGKTTQITQYLDEEGFSNYGMIGCTQPRRVAAVSVAKRVAEEVGCKVGHDVGYTIRFEDVTGPDTRIKYMTDGMLQREALLDPEMSKYSVIMLDEAHERTVATDVLFALLKKAAIKRPELKVIVTSATLNSAKFSEYFLNCPIINIPGKTFPVEVLYSQTPQMDYIEAALDCVIDIHINEGPGDILVFLTGQEEIDSCCEILYDRVKTLGDSIGELLILPVYSALPSEIQSKIFEPTPKGSRKVVFATNIAETSITIDGIYYVVDPGFAKINIYNARAGIEQLIVSPISQAQANQRKGRAGRTGPGKCYRLYTESAFYNEMLENTVPEIQRQNLSHTILMLKAMGINDLLKFDFMDPPPKNLMLNALTELYHLQSLDDEGKLTNLGKEMSLFPMDPTLSRSLLSSVDNQCSDEIVTIISMLSVQNVFYRPKDRQLEADSKKAKFHHPYGDHLTLLNVYTRWQQANYSEQYCKTNFLHFRHLKRARDVKSQISMIFKKIGLKLISCHSDPDLIRKTFVSGFFMNAAKRDSQVGYKTINGGTEVGIHPSSSLYGKEYEYVMYHSIVLTSREYMSQVTSIEPQWLLEVAPHFYKAGDAESQSRKKAKIIPLHNKFAKDQNSWRLSSIRQSRERALGIKR
What is the function of this protein?
Acts late in the splicing of pre-mRNA.  Mediates the release of the spliced mRNA from spliceosomes.
What are the official names of this protein?
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMH_STRGG
Sequence: MSQTRHVPVMLQRCLDLLAPALQDPAHPEPVVVDCTLGLGGHSEALLASFPTARLIALDRDKEALRLSGERLAPYGDRATLVHAVYDELPEVLARLGIPKVQGVLFDLGVSSMQLDEADRGFAYAQDAPLDMRMDQSTGMGAAEVLNTYPPGELVRILRAYGEEKQAKRIVSAVVREREKEPFSNSARLVELIRDALPQAAKRTGGNPAKRTFQALRIEVNGELSVLERAIPAAVDSLDVGGRIAVLSYHSLEDRLVKQVFAAGAANTAPPGLPVVPERYQPRLKQLTRGAELPTEQEVAENRRAAPARLRGAQRIRAEER
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_FLAPJ
Sequence: MQSNQLDYLPIFMQMGLAVGFVVLTIIGSSFLGPKRSSVNKDKNFESGIESIGNARVPFSVKYFLVAILFVLFDVEVIFLYPWAINFQELGMQGMIKMVIFMSLLLVGFFYIIKKKALEWD
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TORS_CAEEL
Sequence: MKLDYVLLLLFHLCFVNTELISVITGKIKDSGTTIAISAGAFWGLKDRLKCYLYECCHEPDVNFNYHTLDADIANLLFGQHLVKDVVVNSIKSHWYNENPRKPLVLSFHGYTGSGKNYVAEIIANNTFRLGLRSTFVQHIVATNDFPDKNKLEEYQVELRNRILTTVQKCQRSIFIFDEADKLPEQLLGAIKPFLDYYSTISGVDFRRSIFILLSNKGGGEIARITKEQYESGYPREQLRLEAFERELMNFSYNEKGGLQMSELISNHLIDHFVPFLPLQREHVRSCVGAYLRKRGRGDLVSNVDFVERVLNSLQYFPESSKAFSSSGCKRVDAKTDLEMAKIRPLLSSVHFDDEL
What is the function of this protein?
May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins.
What are the official names of this protein?
Torsin-like protein, Abnormal oocyte formation protein 5.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. Torsin subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: ENL07_ARATH
Sequence: MMMMMMRSTCNLTLMLCICALVVASMAAEGPRDFKVGDEFGWRVPLQNDSAVYSHWASSNRFHIGDSLSFVYDKDSVMEVDKWGFYHCNGSDPITAFDNGNSTFDLDRPGLFYFISGSNQHCTSGQRLIVEVMHIHQHHDHDASMPPSMSPLSNSASPYASASASSAASSLPTACLLIPLFLTIASFRFISY
What is the function of this protein?
May act as a carbohydrate transporter.
What are the official names of this protein?
Early nodulin-like protein 7, AtENODL7, Phytocyanin-like protein ENODL7.
What is the protein family that this protein belongs to?
Belongs to the early nodulin-like (ENODL) family.
Protein: LPPW_MYCTU
Sequence: MRARPLTLLTALAAVTLVVVAGCEARVEAEAYSAADRISSRPQARPQPQPVELLLRAITPPRAPAASPNVGFGELPTRVRQATDEAAAMGATLSVAVLDRATGQLVSNGNTQIIATASVAKLFIADDLLLAEAEGKVTLSPEDHHALDVMLQSSDDGAAERFWSQDGGNAVVTQVARRYGLRSTAPPSDGRWWNTISSAPDLIRYYDMLLDGSGGLPLDRAAVIIADLAQSTPTGIDGYPQRFGIPDGLYAEPVAVKQGWMCCIGSSWMHLSTGVIGPERRYIMVIESLQPADDATARATITQAVRTMFPNGRI
What are the official names of this protein?
Putative lipoprotein LppW.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: KCNE5_MOUSE
Sequence: MNCSESQRLQTLLNRLLLELHHRGNASGLGIGTGPSMGMGVVPDPFVGREATSAKGNDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKDEPPLACVAEQEWVPAAIASADPENGQGLLAEGGHQLAAGALPALAQGAERV
What is the function of this protein?
Potassium channel ancillary subunit that is essential for generation of some native K(+) currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits.  Functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1.
What are the official names of this protein?
Potassium voltage-gated channel subfamily E regulatory beta subunit 5, MinK-like protein, Potassium voltage-gated channel subfamily E member 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNE family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein.
Protein: RL27_YERP3
Sequence: MAHKKAGGSTRNGRDSESKRLGVKRFGGEAVLAGSIIVRQRGTKFHAGINVGCGKDHTLFALADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GLMU_BACLD
Sequence: MDKRFAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDEARKLSLEKLVTIVGHGAEDVKKQLGEKSEYALQAEQLGTAHAVKQAKSILGSEKGTTIVICGDTPLLTAETMEAMLTEHQKKAAKVTILTAVAEDPTGYGRIIRNENGDVAKIVEHKDATEEERLVKEINTGTYCFDNEALFQTIEQVSNDNVQGEYYLPDVIEILKNQGETVAAYQTVNFQETLGVNDRVALSQAEIYMKQRINKRHMQNGVSLIDPDNTYISPEAVIGRDTVIYPGTVIKGRVVIGEDAVIGQNSELENSTVGSRTVIKQSVIVDSEVGDDVTIGPFAHIRPDSKIGNEVRIGNFVEVKKSEFGDRSKASHLSYIGDAEIGTDVNLGCGSITVNYDGKHKFKTKIENGAFIGCNSNLVAPVTIGEGAYVAAGSTITDDVPGRALSIARARQVNKEDYAENIHKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_THEMA
Sequence: MALAEKFNLQDRFLNHLRVNKIEVKVYLVNGFQTKGFIRSFDSYTVLLESGNQQSLIYKHAISTIIPSSYVMLMPKKQETAQEAETSENEGS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: YR428_MIMIV
Sequence: MSLNTEQASIEFNKMLQNGNTTISVQSMNLIKKIIESDQITNKFNHGVRETIKILNPFHGNKVDIDVDVAQLVKYMWISGIRTTNICSCNESIPRDYVWIEFLDTESMKKFISIVFTGIPNTSDIFSRANKLTGINEGSWIYDLTLMDDNPTTRGFDIKDVYTFISVRFPKSDYKWICKRFEKNIKDNNTCTLF
What are the official names of this protein?
Uncharacterized protein R428.
Protein: PG038_VARV
Sequence: MVYKLVLLFCIASLGYSVEYKNTICPPRQDYRYWYFAAELTIGVNYDINSTIIGECYMSESYIDRNANIVLTGYGLEINMTIMDTDQRFVAAAEGVGKDNKLSVMLFTTQRLDKVHHNISVIITCMEMNCGTTKYNSDLPESIHHKSSCDITINGSCVTCVNLETDPTKINPHYLHPKDKYLYHNSKYGMRGSYGVTFIDELNQCLLDIKELSYDICYRE
What is the function of this protein?
Plays a role in immune evasion.  When secreted, inhibits T-cell activation by preventing the binding of host CD80 and CD86 to soluble CTLA4 and CD28.  In the infected cell, may inhibits host NF kappa B activation.
What are the official names of this protein?
Early protein OPG038, Protein M2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG038 family.
Protein: Y149_MYCGE
Sequence: MKLYRSLKAALLPGICTSILLASCASTNTYQDQRNALISLASNRDTLIANAKKSKEEVQKEVTKMNSSTSSMMTATQSVAITTHQTTEKTNNSKYDLDKLFKDYILYVVDNFSGLVFKRTGGHRIQLIDKDKEILDGGNLTKHTHHDHNHMHNHEHEHEEHHDEEETEVVGRALSFTNGIFLVIDYKKDSERKNMSGSTTMMHQHHHEAEEHKEERKLSLNLKAYKFNTPFNISEFISAWHHKESHNSDTEFNNLHNKYDKEELDIIDYNFEEKAVDETIA
What are the official names of this protein?
Uncharacterized lipoprotein MG149.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PSA2_ORYSI
Sequence: MGDSQYSFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKAANGVVIATEKKLPSILVDETSVQKIQSLTPNIGVVYSGMGPDFRVLVRKSRKQAQQYYRLYKETIPVTQLVRETAAVMQEFTQSGGVRPFGVSLLIAGYDDNGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMELDDAIHTAILTLKEGYEGQISANNIEIGIIRSDREFKVLSPAEIKDFLEEVE
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-2, 20S proteasome alpha subunit B, 20S proteasome subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: OPSD_OTOCR
Sequence: MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFMLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGLVFTWIMALACAAPPLVGWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFFIPLFVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSNFGPIFMTLPAFFAKTASIYNPVIYIMMNKQFRTCMITTLCCGKNPLGDDEASTTASKTETSQVAPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Required for photoreceptor cell viability after birth (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: CYB_ATRSP
Sequence: MANIRKTHPLLKIINGAVIDLPTPSNISAWWNFGSLLGLCLITQVLTGLFLAMHYTADITLAFSSVAHICRDVNYGWLLRNIHANGASFFFICIYLHIARGLYYGSYLYKETWNIGVLLLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAFPYIGDTLVQWIWGGFSVDNATLTRFFTFHFLLPFIIMGATMLHLLFLHETGSNNPTGLNSDADKVTFHPYFSYKDLLGFTILLAILSALALLNPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILVVVPVLHTSKQRSNTFRPPSQTLFWILVANMLVLTWIGGQPVEHPFIIIGQIASVLYFMLFLILIPLTGWLENKILDWA
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GCSH_RHIE6
Sequence: MLKFTAEHEWLELDGDVATVGITTYAVEQLGDLVFVELPEVGKSFSKNDDAATVESVKAASEVYCPLDGEITAVNDAIVADPSLINSDPQGAGWFFKLKLKNRADADGLLDEAAYKELIA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: NQRE_HAES1
Sequence: MEHYISLFVKSVFIENMALSFFLGMCTFLAVSKKVSTAFGLGVAVTVVLGISVPVNQLVYSLILKDGALIDGVDLSFLNFITFIGVIAALVQILEMILDKYFPALYNALGIFLPLITVNCAIFGGVSFMVQRDYNFAESVVYGIGAGTGWMLAIVALAGITEKMKYADVPAGLRGLGITFITVGLMALGFMSFSGVQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXY_PSESM
Sequence: MKRTPHLLAIQSHVVFGHAGNSAAVFPMQRIGVNVWPLNTVQFSNHTQYKQWTGEVLAPQQIPALIDGIAAIGELGNCDAVLSGYLGSAAQGRAILSGVARIKAANPKALYLCDPVMGHPEKGCIVPPQVSDFLLEEAAAVADFMCPNQLELDSFSGRKPESLPDCLAMARALLARGPKAIVVKHLDYPGKAADGFEMLLVTAEASWHLRRPLLAFPRQPVGVGDLTSGLFLSRILLGDDLVAAFEFTAAAVHEVLLETQACGSYELELVRAQDRIAHPRVKFEAVRL
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: THIC_SYNR3
Sequence: MRSAWIEKRRGSANVSQLHYARQGVVTEEMAYVAKRENLPESLVMEEVARGRMIIPANINHANLEPMAIGIASKCKVNANIGASPNASDASEEVKKLELAVKYGADTVMDLSTGGVNLDEVRTAIINASPVPIGTVPVYQALESVHGSIERLSEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGGGILAQWMLYHHKQNPLYTRFEDICEIFKRYDCTFSLGDSLRPGCQHDASDDAQLAELKTLGELTRRAWKHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWHGTAMLCYVTPKEHLGLPNADDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYAFDWNKQFELSLDPERAKEYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDKDLESLEEVLKAKGGAELSTAKLDRAD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: PGK_HYPRU
Sequence: MSLSNKLSITDVDVKGKRVLIRVDFNVPLDENKNITNPQRIAGAIPTIKHALDNGAKAVILMSHLGRPNGAVNAKYSLKPVVPKLEELLGKPVTFAPDCVGPEVEAIVNKADNGAVILLENLRFHIEEEGSSKDKEGNKTKADKAKVEEFRKGLTALGDVYVNDAFGTAHRAHSSMVGVDLPQKAAGFLMKKELDYFAKALESPQRPFLAILGGAKVSDKIQLIDNLLDKVNTLIICGGMAFTFKKVLDNLAIGDSLFDKAGAETVPKLVEKAKAKNVKIVLPTDFITADKFDKDANTGLATDKDGIPDGWMGLDCGDESIKLYKEAIDEAKTILWNGPAGVFEFEKFAGGTKATLDAVVEGCKNGKIVIIGGGDTATVAAKYGVEDKLSHVSTGGGASLELLEGKELPGVTALSSK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_BURCH
Sequence: MSASDLTSVQAAAPQGSRQILVTSALPYANGQIHIGHLVEYIQTDIWVRTLRMHGHEVYYIGADDTHGTPIMLRAEKEGLTPKQLIDRVWTEHKRDFDSFGVSFDNFYTTDSEENRVLSENIYLALQEAGLIAEREIEQAYDPVKEMFLPDRFIKGECPKCHAKDQYGDSCEVCGSTYLPTELLNPYSVVSGATPVRKTSKHYFFRLSDPRCESFLREWVSGLAQPEATNKMREWLGDAGESKLADWDISRDAPYFGFEIPGAPGKYFYVWLDAPVGYYASFKNLCERNGIDFDAWIRPGSKAEQYHFIGKDILYFHTLFWPAMLEFSGHRTPTNVFAHGFLTVDGAKMSKSRGTFITAQSYIDTGLNPEWLRYYFAAKLNATMEDIDLNLDDFQARVNSDLVGKYVNIASRAAGFLIKRFDGRVQDSAMNHPLVAKLRDAIPQIAASYEAREYGRALRHTMELADEVNAYVDGAKPWDLAKDPANAVALHETCSVSLEAFRLLSLALKPVMPRVAVAVEAFFGIAPLAWADAAKPLSSAQPIKAYQHLMTRVDAKQIEALLAANRDSLQAEAAGAAAAGANAAKDAKSNAKASAKPAAVNGADDAPISIDDFAKIDLRIAKIVACQAVEGSDKLLQLTLDVGEEKTRNVFSGIKSAYQPEQLVGKLTVMVANLAPRKMKFGLSEGMVLAASATDEKAEPGLYILEPHSGAKPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCAC_MICDP
Sequence: MKILLVEDDDVLIKVLTKNLTTHHYIVDVVKDGEMGWTYGSTFEYDLIILDIMLPNLDGISLCKRFRAQGYTVPILLLTAQDNITAKVQGLDAGADDYVVKPFDPIELIARIRALLRRGSNNPFPLLTWGDLLLNPSTCEVTYNGCPLNLTTMEYDLLELLLRNCQHVFSSEELLDKLWSSEDFPSEATVRSHVRRLRHKLVAAGAPHDFIATMHGRGYYLKAPSTEEVNNLSVTPENNSHSAAVIVKSRETESDRPQHLIPSDSQQQYLAFLNETWTRTKPQSLDQMGILLQIVRDLQTNQLTPQQQTQAQHVAHKLAGTLGIFGLTKTMHIARQLEYWLGGRERLQPKHAPLMKTLVTALQQDIDHTTLIQLSQIPAGQSPLLLMISADNEFNQSIVAVAASRGIRIQIAPTPDIAPAMLTNEPVLDGFGEDPDVILMRLPSMPSRAEVIEQPNSELSNIWKTLQTFAERYPKLPIVVIGDRGEMSDRLEAMRRGGKLFLVTPTPPEQIVDTVVNLLRDPEIPNKVMILDDDQDWLRTLPTLLKPWGFKVTTLADPQQFWTVLQAVTPDALVLDVNMPQINGFELCQLLRSDPHWQRLPVLFLSVLTDPTTQNQAFAVGGDDYLCKPVKGVELANRILRRLQRVRAWAN
What is the function of this protein?
Required for chromatic adaptation.  Thought to be a positive regulator of phycobiliproteins.
What are the official names of this protein?
Protein RcaC.
Protein: KEFG_SALHS
Sequence: MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSPQTLASHAKAYGEWLANPVSAGGY
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ELP6_ARATH
Sequence: MDRSLNLLDLALGFDEQLAIPSPLNGKVILIEDCVETSGSFVLHQLMKRVLSSNSSDALIFLAFARPFSHYDRILRKLGCNLATHKSNNRLVFFDMLMVKCSDGDQMEDNVSAVAKLFREIQETVRKLQSVTSGNITVMVDDMSLLEIATTGSNSDHVLDFLHYCHTLSSESNCSLVILNHEDIYASMERPAFLLQMVCLADVVIKAEPLASGLANDVHGQLTVLNKGISNSGRGSSRNKLQNFQFRIKENGIDYFYPGCRS
What is the function of this protein?
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity).  The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).  Promotes organ development by modulating cell division rate.  Involved in oxidative stress signaling.  Prevents anthocyanins accumulation (PubMed:19500300).
What are the official names of this protein?
Elongator complex protein 6, AtELP6, Elongator component 6, UPF0405 protein ELP6.
What is the protein family that this protein belongs to?
Belongs to the ELP6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ILVC_YERPN
Sequence: MANYFNTLNLRQQLAQLGKCRFMARDEFADEAGYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVAYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSAVVKAVQPLMKEGAALGYSHGFNIVEVGEQVRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLEFSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVSEGTDAAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGAFSSGMMADWANDDVKLLNWREETGRTAFENAPQFEGKISEQEYFDHGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANAAVPLLKEKFMDSLQAGDLGKSIPGSAVDNAQLRDVNEAIRNHPIEAVGHKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: APOA5_ACIJB
Sequence: MASMIALLTWALALLPALASAQTQKGFWDYFSQSSGDKGKAEQVQRQKLAWEPTSLKDSLEQDLSNIDKFLEKLGPLSGQAREPPALPQDPADMRRQLQEELVEVRARLEPYMAEAHEQVGWNLESLRRQLKPYTAELMEQVALRVQELQEQLRVVGEGTKAQLLGGVDEARGLLRELQNLVAHHTGRVQALFHPYAQRLVSGIGRHVQELHRSVAPHAVASPARLSRCVQTLSRKLTLKAKALHARIQQNLDQLREELSAFAGARADGAVEGTSQDPQVLSQEVRQRLQAFRQDTFLQIADFTRAMDQETEEVQLQLAPPPPGHSAFAPEFLQADSGKALSKLQARLEDLWEDINYSLHDHGLGHQEEP
What is the function of this protein?
Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL (By similarity).  May also be associated with chylomicrons (By similarity).  Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity).  Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages (By similarity).  Binds heparin (By similarity).
What are the official names of this protein?
Apolipoprotein A-V, Apo-AV, ApoA-V, Apolipoprotein A5.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Early endosome. Late endosome. Golgi apparatus, trans-Golgi network. Note=In the presence of SORL1, internalized to early endosomes, sorted in a retrograde fashion to late endosomes, from which a portion is sent to lysosomes and degradation, another portion is sorted to the trans-Golgi network.