PharMolix/UniProtQA huggingface dataset:
Protein: TLR2_CAPIB
Sequence: MPRALWTAWVWAVISAFTEGASDQASSLSCDPTGVCDGHSRSLNSIPSGLTAGVKSLDLSDNEITYVGNRDLQRCVNLKTLRLGANEIHTVEEDSFFHLRNLEYLDLSYNRLSNLSSSWFRSLYVLKFLNLLGNLYKTLGETSLFSHLPNLRTLKVGNSNSFTQIHEKDFTGLTFLEELEISAQNLQLYVPKSLKSIQNISHLILHLKQPVLLLDILIDIVSSLDYLELRDTNLHTFYFSEASISEINTSVKKLIFRNVQFTDESFVEVVKLFNYVSGILEVEFDDCTHDGIGDFTALTLNRIRYLGNVETLTIRKLHIPQFFLFYDLSSIYPLTGKVKRVTIENSKVFLVPCLLSQHLKSLEYLDLSENLMSEETLRNSACEHAWPFLQTLVLRQNRLKSLEKTGELLLTLKNLNNLDISKNNFLSMPETCQWPGKMKQLNLSSTRIHSLTQCLPQTLEILDVSNNNLDSFSLILPQLKELYISRNKLKTLPDASFLPVLSVMRISGNIINTFSKEQLDSFPQLKALEAGGNNFICSCDFLSFTQGQQALARVLVDWPDGYRCDAPSHVRGQRVQDARLSLSECHRAAVVSAVCCALFLLLLLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPRRDLCYDAFVSYSEQDSYWVENLMVQELEHFNPPFKLCLHKRDFVPGKWIIDNIIDSIEKSRKTIFVLSENFVRSEWCKYELDFSHFRLFDENNDAAILILLEPIDKKAIPQRFCKLRKIMNTKTYLEWPTDETQQEAFWLNLRAAIRS
What is the function of this protein?
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components.  Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  May also promote apoptosis in response to lipoproteins.  Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.  Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides (By similarity).
What are the official names of this protein?
Toll-like receptor 2.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Note=Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to diacylated lipoproteins, TLR2:TLR6 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus. Triacylated lipoproteins induce the same mechanism for TLR2:TLR1 heterodimers.
Protein: DCAM_BOVIN
Sequence: MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVINQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIEGFKRLDCQSALFNDYNFVFTSFAKKQQQQQS
What is the function of this protein?
Essential for biosynthesis of the polyamines spermidine and spermine.  Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: ATPE_HYDS0
Sequence: MLKVDIVTPKGIVYTEEVESVNIPAYDGEMGILENHMLLLTQIKPGLVYFNKDDKNGIAVGYGFADITPDKVIILTEEAVPVGNIDLEEYKKVFEEATRKLSDARTAEEISEWQKKREMAETFINIAKHFSPKIKA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CTRB2_PENVA
Sequence: MIGKLSLLLVCVAVASGNPAAGKPWHWKSPKPLVDPRIHVNATPRIVGGVEATPHSWPHQAALFIDDMYFCGGSLISSEWVLTAAHCMDGAGFVEVVLGAHNIRQNEASQVSITSTDFFTHENWNSWLLTNDIALIKLPSPVSLNSNIKTVKLPSSDVAVGTTVTPTGWGRPLDSAGGISDVLRQVDVPIMTNDDCDAVYGIVGNGVVCIDSEGGKGTCNGDSGGPLNLNGMTYGITSFGSSAGCEVGYPDAFTRVYYYLDWIEQKTGVTP
What is the function of this protein?
Serine protease with chymotryptic and collagenolytic activities.
What are the official names of this protein?
Chymotrypsin BII.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: NADK_LATSS
Sequence: MRITVYSNDGSSSRQVADKLTNKLINNGFTMDAQTPEVVISVGGDGTLLSAFHRYADALDQIRFIGVHTGHLGFYTDWRDFEVDDLVVALQEDLGQSISYPLLEVKITYADTNEVQHFLALNEVTLRRYAATLRTDVYIKENFFESFRGDGLCVSTPTGSTAYGKSIGGAVLHPRLEAMQLTEIASINNRVYRTLAAPIVLPSDEWLLLKPSRTSDYVVTIDQFTFKDRPIESMQFKIAKERIQFARYRHTHFWDRVEDAFIGSKHEI
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BRASO
Sequence: MKFLDEAKVYVRSGDGGNGCVAFRREKFIEFGGPNGGNGGRGGDVVIEAVDGLNTLIDYRYQQHFKAQKGENGMGKDRHGAGGKSIVLKVPVGTQIFDEDRETLIHDFTAVGERFVLAEGGNGGFGNAHFKSPTNRAPRHANPGQPGEERWIWLRMKLIADAGLVGLPNAGKSTFLSKVSAAKPKIADYPFTTLHPQLGVVNADGREFVLADIPGLIEGAHEGAGLGDRFLGHVERCRVLLHLVDATCEHAGKAYKTVRHELEAYGGDLTDKIEIVALNKIDAVDPDELKKQRDRLKRAAKKTPILISGATGEGVKEALRKLADVVGEQPVSSKAKNAVESAATEEPWAAPVPPQG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_CLOPS
Sequence: MKLKTLSVGEVNNYVKKLVENDFILKNLNVKGEISNLKFHSSGHIYFSLKDENSKVNCIMFKNNAVNLDFRLEEGMKVEIKARLGVYHKEGTYQLYCENIKKAGIGELFEEFHKLKKELSEEGIFDEKYKRALPKFPKRIGIITAKTGAAVRDIINVIQRRNKSLDIILYPAKVQGENAADSIIEGIRYFNNEKSVDVIILGRGGGFIEELWAFNNRDLAYEIFNSRIPTVSAVGHEVDFTISDFVSDMRAPTPSAAGELVSPSLQEMINDLLNKKEFLHRAIDRKFLNAKRDVDLLYKGLKGNNPKDIIEKRIKEVNSLEEKLNFLGKRKIDKAKDELIALNSILQTLNPLNTLGRGYSVIMDKEDKVINNVSELKKNDMVKVIMKDGSVNIDIKIINE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRD_SALTI
Sequence: MNPWRRYSWEIALAALLIFEILAFGLINPRLLDINVLLFSTSDFICIGIVALPLTMVIVSGGMDISFGSTIGLCAITLGVLFQLGMPLPLAIIITLLLGAICGLINAGLIIYTGVNPLVITLGTMYLFGGSALLLSGMAGATGYEGIGGFPTAFTDFANISFLGIPMPLIFFLVCCLFFWLLMHRTHMGRNVFLIGQSARVAQYSAIPVNRTLYTVYAMTGCASAIAAVLLVSYFGSARSDLGASFLMPTITAVVLGGANIYGGSGSIMGSALAALLVGFLQQGLQMAGVPNQISSALSGALLIVVVVGRSVSLHRHQILEWYSRRRNAHQA
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrD, AI-2 import system permease protein LsrD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G6PI_HELPY
Sequence: MLTQLKTYPKLLKHYEEIKEVHMRDWFFKDKERASRYFLQFESLSLDYSKNRLNDTTLKLLFELANDCSLKEKIEAMFKGEKINTTEKRAVLHTALRSLNDTEILLDNMEVLKSIRSVLKRMRAFSDSVRSGKRLGYTNQVITDIVNIGIGGSDLGALMVCTALKRYAHPRLKMHFVSNVDGTQILDVLEKLNPASTLFIVASKTFSTQETLTNALTARKWFVERSGDEKHIAKHFVAVSTNKEAVQQFGIDEHNMFEFWDFVGGRYSLWSAIGLSIMIYLGKKNFNALLKGAYLMDEHFRNAPFESNLPVLMGLIGVWYINFFQSKSHLIAPYDQYLRHFPKFIQQLDMESNGKRISKKGEIIPYDTCPVVWGDMGINAQHAFFQLLHQGTHLIPIDFIASLDKKPNAKGHHEILFSNVLAQAQAFMKGKSYEEALGELLFKGLDKDEAKDLAHHRVFFGNRPSNILLLEKISPSNIGALVALYEHKVFVQGVIWDINSFDQWGVELGKELAVPILQELEGHKSNAYFDSSTKHLIELYKNYNQ
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_STRP6
Sequence: MLYQQISQNKQGTVVLLVVFFALLALIGASAGYLLLDNYAMGLVLALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFIIEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAVALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQLAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKRSFSSLFSTHPPIEERIERLKNM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIG_MYCAV
Sequence: MSDTTTAFTVPAVAKAVAAAIPDRELIIQGDRRYTYRQVIERSNRLAAYLHSQGLGCHTEREALAGHEVGQDLLGLYAYNGNEFVEALLGAFAARVAPFNVNFRYVKSELHYLLADSEATALIYHAAFAPRVAEILPELPRLRVLIQIADESGNELLDGAVDYEDALASVSAQPPPVRHCPDDLYVLYTGGTTGMPKGVLWRQHDIFMTSFGGRNLMTGEPSSSIDEIVQRAASGPGTKLMILPPLIHGAAQWSVMTAITTGQTVVFPTVVDHLDAEDVVRTIEREKVMVVTVVGDAMARPLVAAIEKGIADVSSLAVVANGGALLTPFVKQRLIEVLPNAVVVDGVGSSETGAQMHHMSTPGAVATGTFNAGPDTFVAAEDLSAILPPGHEGMGWLAQRGYVPLGYKGDAAKTAKTFPVIDGVRYAVPGDRARHHADGHIELLGRDSVCINSGGEKIFVEEVETAIASHPAVADVVVAGRPSERWGQEVVAVVALSDGAAVDAGELIAHASNSLARYKLPKAIVFRPVIERSPSGKADYRWAREQAVNG
What is the function of this protein?
Catalyzes the activation of medium-chain fatty acids as acyl-coenzyme A (acyl-CoA) (PubMed:11690636, PubMed:19477415).  Shows maximal activity with saturated fatty acids of medium-chain length between C6 and C12.  Has lower activity with tridecanoic acid (C13), tetradecanoic acid (C14) and with unsaturated fatty acids like oleic acid (C18:1), linolenic acid (C18:3) and arachidonic acid (C20:4).  Shows weak activity with some aromatic carbon acids (PubMed:11690636).  Involved in the metabolism of fatty acid during mycobacterial survival in macrophages (PubMed:11690636).
What are the official names of this protein?
Medium-chain acyl-CoA ligase Mig, Macrophage-induced gene, Medium-chain fatty acid acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RL6_SALPB
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNALTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MNMA_ECOLI
Sequence: MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFDEPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_PSEAE
Sequence: MTQAFTVVIPARYASTRLPGKPLQDIAGQPMIQRVWNQARKSAASRVVVATDDERILAACQGFGAEALLTRAEHNSGTDRLEEVASRLGLASDAIVVNVQGDEPLIPPALIDQVAANLAAHPEAAIATLAEPIHEVSALFNPNVVKVATDIDGLALTFSRAPLPWARDAFARDRDSLPEGVPYRRHIGIYAYRVGFLADFVAWGPCWLENAESLEQLRALWHGVRIHVADARENMLPGVDTPEDLERVRRVLGG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEUL_OPHUL
Sequence: MQFSIATIALFLSSAMAAPYSGNSNSDSYDPCTGLLQKSPQCCNTDILGVANLDCHGPPSVPTSPSQFQASCVADGGRSARCCTLSLLGLALVCTDPVGI
What is the function of this protein?
Has been implicated in the pathogenicity of this fungus on ELM.  Accumulates at, and plugs intercellular openings in the xylem, or interacts with host parenchyma cells, thereby enhancing respiration and electrolyte loss.
What are the official names of this protein?
Cerato-ulmin, CU, Dutch elm disease toxin.
What is the protein family that this protein belongs to?
Belongs to the cerato-ulmin hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: UBIB_ACIAC
Sequence: MSRLFRGATIVWVVLRYGLDELVLTSFQKPWLRLLARIVSFGRKLDAPRGQRLREALERLGPIFVKFGQVLSTRRDLLPPDIANELALLQDRVPPFDPDVAVATIERAFRRPVGEVFVSFERVPVASASIAQVHFAIVRDRHGVEREVAVKVLRPGMLPVIDNDLGLMRAMAGWVESLSADGKRLKPRQVVAEFDNYLHDELDLIREAANAAQLRRNMERLGLVRIPEILWDFCHPEVLVMERMKGVPISQIERLRAAGVDIRQLARDGVTIFFTQVFRDGFFHADMHPGNIQVSLEPGSFGRYISLDFGIVGSLTEFDKEYLAQNFTAFFRRDYKRVAELHVESGWVPADTRINELESAIRAVCEPYFDRPLKEISLGMVLMRLFQTSRRFHVEIQPQLVLLQKTLLNIEGLGRQLDPELDLWSTAKPFLEKWMLDQMGPQRLWREVKAESPHFAKMLPELPRLLHDYLHHKPHDHRREMQELLAEQRRTNRLLQSIIYGGMGFVLGLLALQFLIRIRFFH
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ATP6_CAEEL
Sequence: MNQVYFLDIFMFVFVLQFLFYFKESMLNTLVKKFLNSLVGVFSYTNTLPLSSVISIFTFIVLLTCCFGGYFTYSFCPCGMVEFTFVYAAVAWLSTLLTFISSEKFSVYMSKPGDTYLKTLSMLLIEIVSEFSRPLALTVRLTVNITVGHLVSMMLYQGLELSMGDQYIWLSILAIMMECFVFFIQSYIFSRLIFLYLNE
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MAEL_HUMAN
Sequence: MPNRKASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSSDWALLREEEKEKYAEMAREWRAAQGKDPGPSEKQKPVFTPLRRPGMLVPKQNVSPPDMSALSLKGDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISNFERGHNQATVLQNLYRFIHPNPGNWPPIYCKSDDRTRVNWCLKHMAKASEIRQDLQLLTVEDLVVGIYQQKFLKEPSKTWIRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCKKIAYCISNSLATLFGIQLTEAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVGSSGFSHFNSSNEEQRSNTPIGDYPSRAKISGQNSSVRGRGITRLLESISNSSSNIHKFSNCDTSLSPYMSQKDGYKSFSSLS
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process.  Required for the localization of germ-cell factors to the meiotic nuage (By similarity).
What are the official names of this protein?
Protein maelstrom homolog.
What is the protein family that this protein belongs to?
Belongs to the maelstrom family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to piP-bodies, a subset of the nuage which contains secondary piRNAs (By similarity).
Protein: GRK7_BOVIN
Sequence: MVDMGGLDNLIANTAYLQARKSSDADSKELQRRRRSLMLPGPQSCEQLRQALATDFHSLCEQQPIGRRLFRDFLATVPAYQEARGFLEEVQSWELAEEGPAKGSALQGLVTTCAAAPVPGRPHPFFSPALVTKCQAATTDDDRASLVELAKAEVMAFLQDQPFREFLASPFYDKFLQWKVFEMQPVSDKYFEEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKNGEKMALLEKEILERVSSPFIVSLAYAFESKSHLCLVMSLMNGGDLKFHIYSVGEPGLDMSRVIFYSAQITCGVLHLHSLGIVYRDMKPENVLLDDLGNCRLSDLGLAVQIQDGKPITQRAGTNGYMAPEILMEKASYSYPVDWFAMGCSIYEMVAGRTPFRDYKEKVSKEDLKQRTLKEEVRFQHSNFTEEAKDICRLFLAKTPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLVEPPFVPDPSVVYAKDINEIDDFSEVRGVEFDDNDKQFFQRFATGAVPIAWQEEIIETGPFAELNDPNRPAGCGEGSSRSGVCLLL
What is the function of this protein?
Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
What are the official names of this protein?
Rhodopsin kinase GRK7, G protein-coupled receptor kinase 7, G protein-coupled receptor kinase GRK7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: PYRG_GEODF
Sequence: MKTKFIFVTGGVVSSIGKGLAAASLGALLESRGLRVTHQKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERYTSARLSKKSNFTTGQVYFSVIEKERRGDYLGGTVQVIPHITDEIKSKIIENAKGSDIAIIEIGGTVGDIESLPFLEAIRQFKADRGAANVLYLHVTLVPFIKTADELKTKPTQHSVKELREIGIQPDILICRCEQDLPRDMKAKIALFCNVEEKAVITSQDAEHIYAVPLALHREGLDEQVVEKLNIWTKAPDLAPWQQVVEKLMNPSHGKVRIAIVGKYVNLTESYKSLSEALTHGGIANDCRVHLTYLDSEKIEQEGIDGLLEDVDGILVPGGFGERGTEGKIKTIEFARTRKIPFFGICLGMQMAVVEYARNVCGLEDAFSSEFKPDCLNPVIHLMEEQKGVSRKGGTMRLGAYPCTLTKGSFAQKAYGTLDISERHRHRYEFNNKNRTVLVENGLVLSGVYKEGDLVEIVEITDHPWFVGCQFHPEFKSKPLNPHPLFKAFIAAALQNKKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: GLMM_CLOBK
Sequence: MGRMFGTDGVRGVANKELTADLAYKLGKAGAFILTEGTHRPKILVGMDTRISGDMLESALVAGILSVGAEAICVGVIPTPAIAYLTRKYNADAGVVISASHNPVEYNGIKFFNKNGYKLSDELEDSIQALIRDDFKDVPVLTGENIGRKIEEDGEAIRDYIDFAKSTIKGDLKGLKVTLDCANGASYITSVEAFKELGAEVHVINNKPDGININRNSGSTHPEDLMEYVVKNNCHMGLAFDGDADRCLAIDEKGNLINGDFILAICGKELKRQGRLKKNTIVVTVMSNLGLDIAMKKEEINTIKTKVGDRYVLEEMLKNDYAIGGEQSGHIIFSDYNTTGDGLVTALQLAHIVKESGKTFSELCSIMKELPQVLVNAKVPNDQKDIYLKDEEIKSEIDTITKNLDGSGRVLIRPSGTEPLVRVMLEGENQKEIDKLAHGLAKLIENKVK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: PRMA_LACJO
Sequence: MKLLAIKVECSYELEDGLSFFMQDELDAQGIESRKRSDFVLEGQKHDSSLVELDDIENLPEDLELTAYFEYKNADKKKIIQKITDKIAEMKGYGLDAGNVSISTKEVADEDWNTAWQKYYHVIDFSRHLAIVPEWEDYQPAFSDQQLIRLDPGLAFGTGGHTTTQLVLLAMERALVKPMSVLDVGTGSGILAIAASKLGASHVLGTDISDEAVTAAKENIALNNIDNIDVRKANLLKDIDEKYDLIVANILADILLELIPDLDNHLNENGKIIFSGIDYLQLPKIEKALEENNFVIKMKMQEGRWIGLLIARKPN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBJ_ACOCL
Sequence: MADTTGRIPLWLIGTVAGIPVIGSVGVFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y441_METJA
Sequence: MVIKLEFEFLLLLPLLIIVGFIVGILGSLFGIGGGFLVAPILTFIFDYFGIPDGVKFAVGTSLFVVFINSIISIFRHAKIKNINWKASITIGIISLVFSYFSGFLVVNFIDSAILKKLFGIFLIANAIYMAKSHHIDKISDREDKLEPFILCGVITGFLSGLFGIGGGIVIIPILAMAKYPVKRAVAISVGVIPLTSIGGLISYLTANTEGYIYNIGYVSIPIALIMAIPIIYSSKLGIKINQKISPKHLRIMLSSILGVMGLFMLL
What are the official names of this protein?
Probable membrane transporter protein MJ0441.
What is the protein family that this protein belongs to?
Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IOLB_LISMO
Sequence: MGKLLRKPLNERIAPGVTLVQDINQGNSPLSYVGFRLIELEEDAVYQETLDGLECCIVALTGKISVSEGDHVFSEIGTRANVFEKIPTDSVFISGGRAFQVKADAEKARVALCYSPADRNLPTTLIKASDNSIEQRGKYQNKRLVHNILPDVSEVASSLLVVEVYTDGGNFSSYPPHKHDHDNLPAESLLEESYYHEINPKQGFIFQRVYTDDRALDETMAVEHQNAVIVPEGYHPVGVPDGYDSYYLNVMAGPKRVWEFHNDPDHEWILERD
What is the function of this protein?
Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).
What are the official names of this protein?
5-deoxy-glucuronate isomerase, 5DG isomerase.
What is the protein family that this protein belongs to?
Belongs to the isomerase IolB family.
Protein: RS17_STAS1
Sequence: MSERNDRKVYVGRVVSDKMDKTITVLVETYKTHKLYGKRVKYSKKYKTHDENNSAKLGDTVKIQETRPLSATKRFRLVEIVEESVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.