PharMolix/UniProtQA huggingface dataset:
Protein: CRCB_VARPS
Sequence: MLLPILAICMGASVGALARWGLALWFGAGGFMPWGTLAANLVGGYLVGVAIASFHLLPDLDPAWRLALVTGFLGGLTTFSSFSAEVVTMLLEGRPGVALLTAAAHLGGSLFLTWLGIRSVQALAA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LACB2_STRP8
Sequence: MKIAVGCDHIVTYEKIAVVDYLKTQGHEIIDCGTYDNVRTHYPIFGKKVGEAVASGKAELGVVICGTGVGITNAVNKVPGIRAALVRDMTSAIYSKEELNANVIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEFLEKWVRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB 2.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: CSN6_EMENI
Sequence: MPDEAISILSQKSSDSGLHIQLHPLALLTISDHITRHAARSQQGPIVGGLLGQHNGREITVEHGFECVVEIGPNGEAQLPNEWFVDRVKQFKDVHKVPALDLIGWWSTAPPSGPTTAHLPIHRQILQNHNESAVFLTFHPSQVQGASQSQGKLPLTIYESVYEGESVTENGKAMQVDGEEQLLNIRFRELPYTIETGEAEMIGIDTVARTARNAAATETSTVAAPSSQIDSDKQEQQPANTDLLSPEEEELIASLNTRLNAIRTLESRISLIKSYLSSISPSSEEGQKDSATKPDHTILRDINSLLSNLSLLTPHEQSAFSAETLAQNNDVSLVALLGQLSQSVNGMREVGKRTAIVNSVRRNRKQLGAQSRYEDDILGRDGVALG
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity).  The CSN complex seems to link protein degradation to sexual development.
What are the official names of this protein?
COP9 signalosome complex subunit 6, Signalosome subunit 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HBA1_NOTNE
Sequence: SLSDKDKAAVKALWSKIGKSADAIGNDALSRMIVVYPQTKTYFSHWPSVTPGHPDIKAHGKKVMGGLAIAVSKINDLKAGLSNLSQQHAYKLRVDPANFKILNHCILVVISTMFPKNFTPQAHVSLNKFLSGVALALAQRYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1, Alpha-1-globin, Hemoglobin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: COAA_NITWN
Sequence: MDSRADQQQYNPYRVFPRAEWAKLRHDMPMTLAANEIAALRSMHDRLDLVEVEEIYLPLSRLLSIYVAAMQRLFVAQRQFLGIHDRKVPYIIGVAGSVAVGKSTTARVLQALLARWSPRPKVELVTTDGFLLPNAVLERRGLMQKKGFPESYDLPMLLSFLSDIKAGRAPVRAPVYSHLTYDIVPDSWIEVSHPDILIVEGVNVLQTGPLPRDGRAIPVVSDFFDFSVYLDAEEPVLRDWYVTRFLALRDSAFQDPRSYFNRYALLSDDEAIATAIAIWERTNRANLEDNILPTRPRANLILKKGADHVVERVALRRL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERB1_ASPNC
Sequence: MSAAKVSKKRKAVTKDVEEEAGVFSGDELNVGDIDGALSDDANDLSSDEEDSEVELVDDFSSDEDEDEEEELDSDEIPSDGEAPLKKKSGTSAADLEVPTNDDESSSEEEQPNFRIEKDANGNDRYIYDEINPDDNSDYSDVEENANTIGNIPLSFYDQYPHIGYDINGKKIMRPATGEALDALLDSIEIPKGFTGLTDPSTGKPLELSQDELELLRKVQMNEIPEEGYNPYEPLMEWFSNKQEIMPLSAAPEPKRRFVPSKHEAKRVMKIVKAIREGRILPYKPPSEEKEEDLELINYDLWADEAERPDHPMHVPAPKLPPPGYEESYHPPPEYLPDNKERKAWQEADPEDREREYLPTDFGSLRKVPGYGEFVKEKFERCLDLYLAPRVRRSKLNIDPESLLPKLPSPEELKPFPSVCATVFRGHKGRVRSLAVDPTGVWLATGGDDGTVRVWELLTGRQLYSVKVGEEDPVNVVRWRPSKDAVVLAAAAGDDIYLIVPPILDPELEQASLDLLDAGWGYAASKPAPKASEEGKKTTPPQWVRPSAALADNGVCAVIPLRYVAKSISWHRRGDYFVTVCPGSSTPASMAIAIHTLSKHLTQYPFSRRIKGGGPPQTAHFHPSKPILFVANQRTVRAYDLSRQLLVKIIQPGARWISSFDIHPTSSTASGGDNLIVGSYDRRLLWHDLELSQRPYKTLRYHRKAIRAVKFHPSGRYPLFADASDDGSLQIFHGSVTGDMLSNASIVPLKVLKGHKITGELGVMDLDWHPREAWCVSAGADGTCRLWM
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein erb1, Eukaryotic ribosome biogenesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: VATB_SULTO
Sequence: MSLLNVREYSNISMIKGPLIAVQGVSDAAYNELVEIEMPDGSKRRGLVVDSQMGVTFVQVFEGTTGISPTGSKVRFLGRGLEVKISEEMLGRIFNPLGEPLDNGPPVIGGEKRNINGDPINPATREYPEEFIQTGISAIDGLNSLLRGQKLPIFSGSGLPANTLAAQIAKQATVRGEESNFAVVFAAIGVRYDEALFFRKFFEETGAINRVAMFVTLANDPPSLKILTPKTALTLAEYLAFEKDMHVLAILIDMTNYCEALRELSASREEVPGRGGYPGYMYTDLATIYERAGKVIGKKGSITQMPILTMPNDDMTHPIPDLTGYITEGQIVLDRSLFNKGIYPPINVLMSLSRLMKDGIGEGKTRDDHKDLSNQLFAAYARAQDIRGLAAIIGEDSLSEVDRKYLLFAEAFERRFVAQGVNENRSIETTLDIGWEVLSILPESELSLIRSEYIKKYHPNYRGKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, Sul-ATPase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: 3S1A_HYDTO
Sequence: MTCCNQQSSQPKTTTNCAGNSCYKKTWSDHRGTIIERGCGCPQVKSGIKLECCHTNECNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Toxin aagardi.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURC_STAA1
Sequence: MTHYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIENYVFTEVALRNKGIKILPFDANNIKEDMVVIQGNAFASSHEEIVRAHQLKLDVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPIYYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIETARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDSINVLEQFDNAVVLFMGAGDIQKLQNAYLDKLGMKNAF
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_SALSV
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVAAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKIADLKGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKSDAPDLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRPB_BACSU
Sequence: MNEQKTNDLILQTATKLVSFIILLFSFYLFLSGHNAPGGGFVGGLITSSSIVLLLLAYDLKTVRSLLPVNFIYVAGAGLLLAVLTGVGSFVFGAPFLTHTFGYFQLPILGKTELATATIFDLGVYLVVVGITMTIIQTIGEEE
What is the function of this protein?
Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis.  Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB.  MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance.  MrpA is required for initiation of sporulation when external Na(+) concentration increases.  Also transports Li(+) but not K(+), Ca(2+) or Mg(2+).
What are the official names of this protein?
Na(+)/H(+) antiporter subunit B, Mrp complex subunit B, Multiple resistance and pH homeostasis protein B.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMG_DESVV
Sequence: MSTIRKPSPPDMYDCIVVGAGHAGCEAAMALARMGHATLLLTGNADRIGHLSCNPAIGGLAKGHMVKEIDALGGMMGLWADEAGIQFRTLNSSKGPAVRATRAQIDRDAYLRVVRRDIFAQPNLRVWQDMAESIIVEGGRAAGVRTAYGQEFRAHHVLLTTGTFLQGRIHVGLNNFPGGRLGDAPATGLSASLRAIGLELGRLKTGTTPRLLRDSIDFSLMEVQPPDDPPRPFSFRGPGVRLPQLPCHVTWTNERTHEAIRAGFDRSPMFTGVIKGTGARYCPSIEDKVARFPEKERHQVFVEPEGLESPECYPNGIPTSLPLEVQKAMIATIPGLENAQIVRPGYAIEYDYADPVQLRSTLETKALRGLWLAGQINGTSGYEEAAAQGLWAALNVSCTLRSMPPFLPGRDTAYMAVLVDDLVTKGTREPYRMFTSRAEHRLLLRENNADARLTETGRALGLVDDTHWQRFSTKRAALHSLLDELENRRITPDAAARDIFSRLGEPAPTKGVSLADILRRPSLTLPDLAPFWEGVTRFADDVREEAETIVKYSGYLARQQELVARSARMEDTVLPEDMDYTVIPGLTREIVEKLGKVRPHTLGQAARISGVTPAALTCLEIQLRKMGQR
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_COXB2
Sequence: MLKAPRFWYQPRSLLGGILSPFSFLYQIIVRIRRGLYAVGLKKISKFPVSIVIVGNITVGGSGKTPFVIWLANELKNRGFRPGVVSRGYGGKANRFPQTVTENSDPLQVGDEAVLLMKKIDCPMVVCRDRGAAVKHLLRNFQCDVVIGDDGLQHYSLGRDLEIALLDDRHLGNGRCLPAGPLREPKSRLNTVDFVVPKQLRPNEIYQLKNPAKKIDFNELKELTVHAVAGIGNPGYFFKQLETLGANVIAHPFRDHYFYRSEDFNFDDDHLIILTEKDAIKCKQFDDERLFCFSVDAVVPDQFQNDFFRLISNIILRKQAQREGI
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: PSBE_MESVI
Sequence: MAGSTEERPFSDIITSIRYWVIHSITIPSLFVSGWLFVSTGLAYDVFGTPRPNEYFTEDRQDIPLITDRFNALEQLNQYTK
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AROA_RHIL3
Sequence: MLNGSASKPATARKSAGLTGSVRIPGDKSISHRSFMIGGLASGETRITGLLEGEDVINTGRAMQAMGARIRKEGAQWVIEGTGNGALLAPDAPLDFGNAGTGVRLTMGLVGTYDFHSTFIGDASLSKRPMGRVLNPLREMGVQVSASEGDRLPVTLRGPGTPSPIRYRVPMASAQVKSAVLLAGLNTPGVTTVIEPVMTRDHTEKMLQGFGAALSVETDGDGVRTIRLEGRGKLAGQVIDVPGDPSSTAFPLVAALIVPGSDITIVNVLMNPTRTGLILTLQEMGADIEVVNARLAGGEDVADLRVRHSELKGVTVPEDRAPSMIDEYPILAVAACFAEGATVMKGLEELRVKESDRLSAVADGLKLNGVDCDEGEDFLIVRGRPDGKGLGNAADGRVSTHLDHRIAMSFLVLGLASEHAVTIDDAAMIATSFPEFMQLMTGLGAKIELVAE
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_NITEC
Sequence: MKNNDTIAAIATPPGRGGIGIVRISGTNLEQLAQTILGKLPDPRHAGLFNFLDQNNQVIDQGIVLYFPSPNSYTGEDVLELHGHGGPAVMNLLLTRCLQLGARLAEPGEFTLRAFLNEKLDLAQAEGVADLIEASTANAARCAVRSLHGEFSSAIHQLVSALIDLRVLVEATLDFPEEEIDFLQSAHAVEQLASIQTKLEQVLSASRRGNLLQEGIKVVLTGQPNVGKSSLLNRLAGDEIAIVTEIPGTTRDTIRQSIEIEGIPLHLIDTAGLRETSDIVEQHGIARAYAAIEQADLVLLLVDGRYGVTKEDHSVLARLPKELPVLTVHNKIDLSGQLSRIEEDTSGTAIYLSVKSGEGIELLRTVLLKTVGWQTNIAGEGAYMARQRHLQALLHAKELLKRAETWLHTADQLEILAEELRLAQQALSSITGEFTSDDLLGEIFSNFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_CLOBL
Sequence: MENILDFTLEELKEWLISKEEKAFRAKQVFDWIYNKLIFDFNNMKNIPYKTKNLLSDNFYVGVPKVVKKLMSQDKNTYKFLFEYKDGNIIESVVMKYKHGNSICVSTQVGCRMGCKFCASTLDGVIRNLTSGEILSQIMAAQKEIGERISNVVLMGSGEPLDNFQNVTKFLDLVTSDTTLNIGQRHITLSTCGIVPKIKELADKNYNITLAISLHSPEDLLRKEMMPIANKYSIKELMEACDYYINKTNRRITFEYALVKGKNDSIKEAKKLSTVLKGKLCHVNLIPVNEIKENSYEKSTLKNIESFGNILKENGIETTIRREMGADINAACGQLRRSYVSK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNR1_ECOLI
Sequence: MRLFGYARVSTSQQSLDIQVRALKDAGVKANRIFTDKASGSSSDRKGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVSIRFIDDGISTDGEMGKMVVTILSAVAQAERQRILERTNEGRQEAMAKGVVFGRKRKIDRDAVLNMWQQGLGASHISKTMNIARSTVYKVINESN
What is the function of this protein?
This protein catalyzes the site-specific recombination of the transposon and also regulates its frequency of transposition.
What are the official names of this protein?
Transposon gamma-delta resolvase, Transposon Tn1000 resolvase.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: FTSZ_STAA8
Sequence: MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQIGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGGTGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLDIVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEAAKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINPELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTSVNTSSNATSKDESFTSNSSNAQATDSVSERTHTTKEDDIPSFIRNREERRSRRTRR
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: RF1_MAGSA
Sequence: MNLETQFDKVLYRHDEVRAQLSSGEGMDSQTIQRLSKELSELDPVVTAVQAFRKAREDMVQAAEMMNDPDMKDLAEEEFYALKERLPALEREVQIMLLPKDEADEKNAIIEVRAGTGGEEAALFAAELFRMYERYAGLHGWRFEVMDVNDTGIGGVKEASATITGRNVFARLKFESGVHRVQRVPATESQGRIHTSAATVAIMPEAEEVDIQLNDSDLRFDVYRSQGSGGQSVNTTDSAVRVTHIPTGLAVACQQEKSQHKNKATALKLLRARLYERERSAKDAERAAARKSQVGSGDRSERIRTYNFPQGRVTDHRINMTLYKIDAVMSGDALDELVEALVAADQAERLAEME
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIX1_ASHGO
Sequence: MTSQVVPLSTFVQHLESCEGYEFRTMIKMLASPAYAKQQLLKDELSVFMAKVLKLLRSKDDYQVWKGCHIATVFCTYNPVVLCSFGGELMGILYRALEDATKYYGDSVQTEQRKVMVRALVKTLDTLMDLIRGKPSLTREALTPHLSAIIPMLISFGRCEPNLSLPVIKKLLSKHSTTFRPHVGKLKQLLTELYGHYQSLDPVTRKVVCDTAAYLHLTQKPGNNANEHQAHHKSFPDEHWRAGLFSVLSQFGPVVRLWGEILDIGSDENLARLLETLPRDTANDTSPLLPALTVDINKPVTLWHISARLEQLTDMVESFIRLPTLFPTRIPLGELVKVSEILLSLTTNYLPLKRGLRRDAALTGSIRSALPETQLQGIRLLRCLSDHIGKNLITYMPAILSSMELFIPLKDKKTSIDYQKCVDLQNGLLQLTALMNSIAQHLGHKVEEMSLAIKLVDICAYIIEHKQNLDSAFSSTSGTAKAAGGAKKKEYKAKTGSMSDLFSHPHKFLHPVPLENYTVVNTYYNMALTHWKLPSTQQAKITKYCIYYSLSFKEKLGYIPQTFIELLNTIVLFPGKDRFSILPIAVHLLKETGDPVFDVLCNPKLPLEMIQIRRQPTSSEDDTATSEAEEYAAPADQDDEHLSDDEHTTVDDGVATNAVMGLNNLVSSETLRSEQDSALETQHPEQARTSNLVPDEASEGREDARIFKKRSSSDEQDPPSKRTRAVAAQTPVPAAVPVDNGEPESDDGSDFEIPEIELSDADEE
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits.  Regulates pre-60S association of the critical remodeling factor MDN1.
What are the official names of this protein?
Pre-rRNA-processing protein RIX1.
What is the protein family that this protein belongs to?
Belongs to the RIX1/PELP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL30_RHOE4
Sequence: MADLKVTQIKSIIGTKQNQKDSLRTLGLKGIRQTVVREDNAQNRGLINVVRHLVTVEEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ILVC_BORPA
Sequence: MKVFYDKDCDLSLVKGKTVAIIGYGSQGHAHALNLHDSGVKVVVGLRKGGASWNKAANAGLEVAEVAEAVKRADIVMMLLPDENIAAVYRDEVHANIKAGAALAFAHGFNVHYGQVVPREDIDVIMVAPKAPGHTVRSTYSQGGGVPHLIAVYQDKSGSARDVALSYASANGGGRAGIIETNFREETETDLFGEQAVLCGGTVELIKAGFDTLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEFGEYETGPKVVTDATRQAMRECLTAIQTGEYAKKFILENAAGAPTLTSRRRINAESQIEQVGGKLRAMMPWIAANKLVDKAKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MOLA_HAEIN
Sequence: MKLKSLLIACLLSSLSFSALADRIITDQLDRKVTIPDHINRAVVLQHQTLNIAVQLDATKQIVGVLSNWKKQLGKNYVRLAPELENMAMPGDLNSVNIESLLALKPDVVFVTNYAPSEMIKQISDVNIPVVAISLRTGEVGEKGKLNPTLTDEDKAYNDGLKQGIELIAEVFEKKQQGDELVKAAFANRKLLADRLGDVSADKRVRTYMANPDLGTYGSGKYTGLMMEHAGAYNVAAATIKGFKQVSLENVLEWNPAVILVQDRYPDVVPQILNDQGWANIQALKDKKVFLMPEYAKAWGYPMPEALALGEVWLAKALYPQRFQDVDLDKMVNDYYQKFYRTSYKPDNAAR
What is the function of this protein?
Part of the ABC transporter complex MolBCA involved in molybdate import (PubMed:22078568, PubMed:24722984).  Functions as a low-affinity molybdate transporter (PubMed:24722984).  Binds to both molybdate and tungstate, but not to sulfate or phosphate (PubMed:22078568).
What are the official names of this protein?
Molybdate-binding protein MolA, Molybdate/tungstate-binding protein MolA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 8 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SIR_SYNY3
Sequence: MVTTPTAAPRKPSKVEGIKERSNYLREPLATELLNDANYFTDDAVQILKFHGSYQQDNRDNRVKGQEKDYQFMLRTRNPGGLIPAQLYTALDDLSKTHGNQTLRVTTRQGLQIHGIVKKDLKMAIATVVNNLGSTLGACGDINRNVMAPAAPFRDKPEYGYAWDYANKVADLLSPQSGAYYEIWLDGEKVISGEEAPEVKAARQKDLNGTNLNDPKEPIYGQQFMPRKFKISVTVPGDNSIDVYTHDISLVVITDRHGELRGFNVLAGGGLGRTHNKEETFARAADPIGYVSKDDVYDLVKAIVATQRDYGDRHNRRHARMKYLLADWGVEKFRKQVETYMGKPFQSFKPLPAWRYQDYLGWHEQGDGKLFFGLSVENGRIKDEGDFQLKTALRKVVDQFQLPLRLTANHNILLYDINAQDKAAIEQIFQQHGVVTDPEAIDTLVRYSMACPALPTCGLAVTESERIMPSVNARLRDLLNSLDLPNESIVTRMTGCPNGCARPYMAEIGFVGSAPNSYQVWLGGSPNQERLAAAYTEKMPLEQLESLFEPLFVYFKQSRKGKESFGDFCHRVGFTALREFSHGYTAPAKGGKNRKNQRRVSLSDEMYAQLKARSERDNCPMNQIVQQALTAYLGK
What is the function of this protein?
Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.
What are the official names of this protein?
Sulfite reductase [ferredoxin].
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: LDH_MESFL
Sequence: MKKTSNKVVLVGTGAVGMSFIYSAVNQGLAEEYVLIDVNTKAAEGNAIDIQDTMAVLDKPFTIKAGTYEDCKDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASNPCDVLTTVYQQVTGYDEHSVVGAGTTLDSARLRRLVAEKLNVAPKSVNAYIMGEHGDSSVAAYSKATVMGQPISKYLAEGKITEADLEECWTRAIRMAYEIIERKGATYYGIGVCLNAISSAILRDEKTTFMVGAKLNGEYGQKGFYTGVPVILGSKGWETIIEWDLSDAEKAAFKKSCDALDATYQKAKEAIA
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLI_HALH5
Sequence: MKLCYNQATTLENSNLVKDLEYCEKNGYDYIEIRTMDKLPEYLKDHTLDELKHFFQTNHIKPLALNALVFFNNRDEAGYKEIITEFKGMMETAKALNIPYVVAVPLVTEEKILKSEIKRSCVNVLTELSEIAKPYGVKVALEFIGHPQCTVNTFGQAYEIVEAVGRDNIGLVLDCFHFHAMGSNISDLEKADISKIFILHMDDTEDFPVGFLTDEDRVWPGHGAINLDQMLSILKEKGYSGAVSVELFRPEYYQLSAEEAIKTAKDTTVEVVSKHFTLETTK
What is the function of this protein?
Involved in the reversible interconverion of 2-keto-myo-inositol (2KMI, inosose or 2,4,6/3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5/4,6-pentahydroxycyclohexanone).
What are the official names of this protein?
Inosose isomerase, 2-keto-myo-inositol isomerase, 2KMI isomerase.
What is the protein family that this protein belongs to?
Belongs to the IolI family.