PharMolix/UniProtQA huggingface dataset:
Protein: MTH3_HAEIN
Sequence: MIDCIYNSDSIFEIKKLDSNSIHAIISDIPYGIDYDDWDILHSNTNSALGGTSSAQHKTSLFKRRGKPLNGWSEADKKRPQEYQEWVESWSNEWFRVLKSGSSVFVFAGRQFAHRVVVAFENSGFTFKDMLSWEKDKAPHRAQRISCVFERRGDIANTNKWVGWRVANLRPLFEPILWFQKPYKTGSTLADNLIKHEVGAWNENSLTHWNIQQGALNHSNILKVRITSEDKGYHVAQKPLNLMKLLIDLVTKEEQIVLDPFAGSGTTLLAAKELNRHFIGYEKNNGIYNIAVNRLGIEKNNCFYNKEKK
What is the function of this protein?
A beta subtype methylase that recognizes the double-stranded sequence 5'-AAGCTT-3', methylates A-1 on both strands, and protects the DNA from cleavage by the HindIII endonuclease.
What are the official names of this protein?
Type II methyltransferase M.HindIII, M.HindIII, Adenine-specific methyltransferase HindIII, Modification methylase HindIII.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: GLMM_FRATT
Sequence: MAKYFGTDGIRGEVANSTITVEFTQKLGNAVGSLINQKNYPKFVIVGQDTRSSGGFLKFALVSGLNAAGIDVLDLGVVPTPVVAFMTVKHRAAAGFVITASHNKFTDNGIKLFSSNGFKLDDALEEEVEDMIDGDFIYQPQFKFGSYKILANAIDEYIESIYSRFAKFVNYKGKVVVDCAHGAASHNFEALLDKFGINYVSIASNPDGLNINVGCGATCVSNIKKAVKEQKADLGISLDGDADRIIIVDENGQEIDGDGILNILAQYSDICGGTNGIVGTQMTNMSYENHYRANKIPFIRSKVGDRYVLEDLVKYGYKIGGESSGHVINLNFGTTGDGLFTAIQLLAIFSQADKPVSEFKLQGELMQQTLINVPLTKKVAREDLQKVASDVNDVEKRLGNRGRVLLRPSGTEPVLRVMVEADDKSLATNEAEYLVEKVKQKLV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y2363_STAAM
Sequence: MMKLNLFINANETESYIDIHAPKMNDHVQSIINAVNDLDKSHTLVGYIDKEIHIINVSDVITFQVINKNVTAITSNQKFKLKLRLYELEKQLPQHFIRISKSEIVNKYYIEKLLLEPNGLIRMYLKDAHYTYSSRRYLKSIKERLSI
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator SAV2363.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFE_METJA
Sequence: MIKEKRKVEVIGLELPIFKGGEQINLSELIAQYPIEDGDIIVIAETLISKLEGGVIDRDKIIPSKEAIELAKKTGKDPKVVQVILDEAKEIVKVGKNFIITETKHGFVCANSGVDESNIYKGIKILPKNPDESAEKIRKEIEKLTGKRVGVIISDSVGRPFRKGAVGIAIGVSGILALWDRKGEKDLFGRELKTTEVAIADELASMANVVMGEADEGIPVVIIRGANVPFGNGKGRDLIRPKEEDVFRN
What is the function of this protein?
Catalyzes the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates.  Cannot use F420-2 as substrate to add more glutamates.  Exhibits maximum activity with GTP, compared with UTP (66%) and dGTP (25%); with ATP, only F420-1 is observed as the product; CTP and TTP support no activity.
What are the official names of this protein?
Coenzyme F420:L-glutamate ligase, Coenzyme F420-0:L-glutamate ligase, Coenzyme F420-1:gamma-L-glutamate ligase, F420:glutamyl ligase.
What is the protein family that this protein belongs to?
Belongs to the CofE family.
Protein: ATPH_TETOB
Sequence: MNPIVAAASVVSAGLAVGLAAIGPGMGQGTAAGYAVEGIARQPEAEGKIRGALLLSFAFMESLTIYGLVVALALLFANPFAS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PSD_BRUSU
Sequence: MSLTDTIRNTFVPIHREGYPFIAGFFVVSLILGWLWDPLFWIGMVLTVWCIYFYRDPERVTPMDDDLVISPADGKVSFVGLAVPPAELDLGYEPMTRVSVFMNVFSVHINRSPVRGKIDKVVHRPGKFLNAELDKASTENERNSVLIESPHGKVGVVQIAGLVARRIVCWSNQDDELSVGERFGLIRFGSRVDVYLPSDATVRVAVGQTAIAGETVLADYGTERGEPVVRIA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MRS2C_ORYSJ
Sequence: MDHDPKERLLLPPRAAAAAAANGPHRRAAPAAGGGGGGVAIDVHGLKRRGGGRRSWVRVDAATGASEAVEVAKPALMRRLDLPARDLRLLDPLFVYPSAILGRERAVVCNLERIRCIITADEALILRDPDVAGGGAETEEAVRRYVAELQRRLVDRADDLPFEFIALEVALEAACSFLDAQAVELEADAYPLLDELTTKISTLNLERVRRLKSKLVALTRRVQKVRDEIEQLMDDDGDMAEMYLTEKKRRMEASLLEEQAFQGMGNSGFGSSFSAPVSPVSSPPASRRLEKELSFARSRHDSFKSADSSQYSIEELEMLLEAYFVVIDYTLSKLTSLKEYIDDTEDFINIQLDNVRNQLIQFELLLTTATFVVAIFGVVSGVFGMNFEVDLFNVPHAFEWTLVITGVCGLVIFCCFIWYFKKRRFFPL
What is the function of this protein?
Magnesium transporter that may mediate the influx of magnesium.
What are the official names of this protein?
Magnesium transporter MRS2-C.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PFP_METMH
Sequence: MNKPKKVAILTAGGLAPCLNSAIGSLIERYTEIDPSIEIICYRGGYKGLLLGDSYPVTAEVRKKAGVLQRFGGSVIGNSRVKLTNVKDCVKRGLVKEGEDPQKVAADQLVKDGVDILHTIGGDDTNTAAADLAAFLARNNYGLTVIGLPKTVDNDVFPIKQSLGAWTAAEQGARYFMNVVAENNANPRMLIVHEVMGRNCGWLTAATAQEYRKLLDRAEWLPELGLTRESYEVHAVFVPEMAIDLEAEAKRLREVMDKVDCVNIFVSEGAGVEAIVAEMQAKGQEVPRDAFGHIKLDAVNPGKWFGEQFAQMIGAEKTLVQKSGYFARASASNVDDMRLIKSCADLAVECAFRRESGVIGHDEDNGNVLRAIEFPRIKGGKPFNIDTDWFNSMLSEIGQPKGGKVEVSH
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis.  Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis.  Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
What are the official names of this protein?
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, 6-phosphofructokinase, pyrophosphate dependent, PPi-dependent phosphofructokinase, PPi-PFK, Pyrophosphate-dependent 6-phosphofructose-1-kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPB_YEREN
Sequence: MSNKMTGLVKWFDAGKGFGFISPADGSKDVFVHFSAIQGNDYKTLDEGQNVEFSIEQGQKGPSAVNVVAL
What are the official names of this protein?
Cold shock-like protein CspB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOCO2_CULQU
Sequence: MAMEQFESVFTAKENAEIAKEFTRLKDTCYLDHAGTTLYADSQIRAVGDCLTGSLFCNPHTSRTTEDLLDQVRFRVLRHFGTHPSEYGLVFTSGTTGALKLVAECFDFGDEGAFVYTRDNHTSVLGMRAVVGTERIVPIGREDLRGGRSTGGGKSSLVVFPAQCNFNGFKYPLGLVEDIQRNGLVGFDGDRFHVCLDAASFVSTNALDLAKHQPSFVCLSFYKIFGFPTGLGALLVHRSAQNLLKKRYYGGGTVKIAMAGRNFHVKRDSLADQFEDGTVPFTSIISLLQGFETLERLVPASGELSSIDRVSRHTFALGRYCFQRLRGLRHANSNSVVKLYHDTEFEDRGSQGGIVNFNVLHEDGSFVGFAEVAYMASVHNVVLRTGCFCNPGACQRLLELTDEDVLKQFNAGHVCGDANDLIGGQPTGSVRVSFGYMSRREDVDRLVEMVEKCYVKKMTANGLTRKQIVSNYKNYDQPKLKMICLFPIKSCGAYKITTSWPLCHKGLKHDREFVIVDENGVAMTQKKLVEMCLIKPKIDIKTNTLILTHPAMENFTLSMEPLSNESQSIKLCQTKVCQDNVQAIDCGDAVANWISIALQTSGLRLLKQSDDEARTLRKSTTEIALSNQAQFLLINQASVRWLADLVPDWDDLSQEPTLESLVDRFRGNLIIDSVKPLEESSWTQLRIGPLEFSVDGPCSRCQMICIDQSSGTRTAEPLRTIAREFKGKMRFGIYLSHVKSLEGSDEKLLHCGSPLQVVAE
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase 2, MCS 2, MOS 2, MoCo sulfurase 2, Molybdenum cofactor sulfurtransferase 2, Protein maroon-like 2, Ma-l 2.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Protein: ATPA_HORVU
Sequence: MATLRVDEIHKILRERIEQYNRKVGIENIGRVVQVGDGIARIIGLGEIMSGELVQFAEGTRGIALNLESKNVGIVLMGDGLMIQEGSFVKATGRIAQIPVSEAYLGRVVNALAKPIDGKGEIIASESRLIESPAPSIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQGVICVYVAIGQRASSVAQVVTTFHEEGAMEYTIVVAEMADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNSLLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELQAFAQFASALDKTSQNQLARGRRLRELLKQSQANPLPVEEQIATIYTGTRGYLDSLEIEQVNKFLDELRKHLKDTKPQFQEIISSSKTFTEQAEILLKEAIQEQLERFSLQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SHPS1_HUMAN
Sequence: MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVLVAAGETATLRCTATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNTAAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREITQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNRTPKQPAPKPEPSFSEYASVQVPRK
What is the function of this protein?
Immunoglobulin-like cell surface receptor for CD47.  Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane.  Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment.  May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity).  Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin.  Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation.  CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.  Plays a role in antiviral immunity and limits new world arenavirus infection by decreasing virus internalization (By similarity).  Receptor for THBS1 (PubMed:24511121).  Interaction with THBS1 stimulates phosphorylation of SIRPA (By similarity).  In response to THBS1, involved in ROS signaling in non-phagocytic cells, stimulating NADPH oxidase-derived ROS production (PubMed:24511121).
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Bit, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha-1, Sirp-alpha-1, Signal-regulatory protein alpha-2, Sirp-alpha-2, Signal-regulatory protein alpha-3, Sirp-alpha-3, p84.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL4_COXBR
Sequence: MELPVNSFDKKEASTLTVADSAFGSEYKEGLVHQVVNAYLAGGRAGTKAQKTRREVSGGGAKPWRQKGTGRARAGSSRSPLWRSGGVAFAAKPRDFTQKVNRKMYRSAMASILSELIRREQLVVVDSLKLNEPKTRELKESLKKLNLGNVLIIIDGDDRNINLASRNMVGVSVCDALHVDPVSLVAAENIVVTVDAVKRLEERLS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SYG_TREPA
Sequence: MEKIVGLCKRRGFVFPSSEIYGGQGGVWDYGPMGIALKNNIAHAWWQDMTRLHDHIVGLDAAILMHPNVWRTSGHVDHFSDPLVDCTVCKSRFRADQVAVPSAGGPCPQCGGALTGVRNFNLMFSTHMGPTDERASLLYLRPETAQGIYVNYKNVLQTTRLKVPFGIAQIGKAFRNEIVTKNFIFRTCEFEQMEMQFFVRPAEDTHWFEYWCAQRWAFYQKYGVRMNHMRWRTHAAHELAHYARAACDIEYAFPMGFRELEGVHNRGDFDLTRHAQHSGKDLCYVDPDPNLDAAARRYVPCVVETSAGLTRCVLMFLCDAYTEEYVQAPNVAFSETTQTADQEGAARTGEMRIVLRLHPALSPTTVAFLPLVKKDGLVDLARAVRDELREDFACDFDAAGAIGKRYRRQDEVGTPFCVTVDYQSKEDDTVTVRLRDSMAQRRVSRAFLAEFLRTEIKHYRRP
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C13A3_CAEEL
Sequence: MSLSILIAIALFIGVFTYYLWIWSFWMRKGIKGPRGLPFFGIINAFQSYEKPWILRLGDWTKEYGPMYGFTDGVEKTLVVSDPEFVHEVFVKQFDNFYARKQNPLQGDPDKDPRIHLVTSQGHRWKRLRTLASPTFSNKSLRKIFSTVEESVAEMMRHLEKGTAGGKTIDILEYYQEFTMDIIGKIAMGQSGSMMFENPWLDKIRAIFNTRGNIIFIICGIVPFTGSIFRWFFSKVPTAQTVTSLMHTLEIALTKRVEQRAADEKAGIESSGEPQDFIDLFLDVQADTDFLEDETKNGFARSQIVKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDRECPDPEVTFDQLSKLKYMECVIKETLRLYPLASIVHNRKCMKSTTVLGMKIEEGTNVQADTWTLHYDPKFWGENANEFKPERWESGDEQAVAKGAYLPFGLGPRICIGMRLAYMEEKMLLAQILKKYSLETTFETHIPLKLVGIATTAPTNVHLKLKPRHSD
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Putative cytochrome P450 CYP13A3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RODA_MYCLE
Sequence: MTTQLQPVVTVTPPLPTRRNAELLLLGFAAVITVAALAIVEANQERNFRWYLAGYGLIFWSLFASAHLAIRRFAPYTDPLLLPIVALLNGLGLVMIHRLDLVDNDVTGHHHTSAAQQMLWTLVGVAAFVLVMTVLKDHRQLARYGYISGLTGLVFLAIPAPLPEQNGAKIWIRFPGFSIQPAEFSKILLLIFFAAVLVAKRSLFTSAGKHLIGMTLPRPRDLAPLLAAWVISVSVMVFEKDLGTSLLLYASFLVVVYLATQRLSWVIIGLVLFTAGSTIAYFTFEHIRVRMQVWWDPFTNLDVGGYQIVQSLFSFATGGIFGTGLGNGQPDAIPAASTDFIIAVFGEELGLVGLAALLMLYTIVIVRGLRTAIATRDSFGKLLAAGLASTLAIQLFIVSGGVTTLIPLTGLTTPWMSYGGSSLLANYVLLAILARISHSARHPLRSRPHNTSPIAVASTEVIERV
What is the function of this protein?
Transglycosylase involved in peptidoglycan cell wall formation.  Required for the regulation of cell length.
What are the official names of this protein?
Peptidoglycan glycosyltransferase RodA, Non-canonical transglycosylase RodA.
What is the protein family that this protein belongs to?
Belongs to the SEDS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIR2_EHV1B
Sequence: MSIENSKEAALTAELSLAGAFFYTPECPDIEHLRSLSVANRWLDTDLPISDDLKDVAKLTPAEREFYRFLFAFLSAADDLVNLNLGDLSALFTQKDILHYYIEQESIEVTHSRVYSAIQLMLFGNDAAARARYVASIIGDAAIGRKVAWLQAKVRECGSVAEKYILMILIEGLFFASSFASIAYLRTHNLFVVTCQSNDLISRDEAIHTRASCCIYNNYLGGFEKPEPKRIYELFSEAVNIECEFLLSHAPQYSHLLDIGAIISYVRYSADRLLGEIGLSPLFNAPKPSPSFPLAFMTVEKHTNFFERRSTAYSGTLINDL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: SNF7_CANGA
Sequence: MWASIFGGKGNTNKELPKKAIIELREHINLLSKKQAHLQGQITAQENEARKFLTRGNKTMAKNALKKKKVYEGQLVKLESQMDSLEQQLFSIESANLNLETMRAMKQGAKAMKSIHSGLDIDRVDETMDEIREQVELGEEISDAISRPLYTGANEIDEDELDEELDMLAQETEPQVATKEQALPESKQALSMPNIPNTKIDESKTKIEEEEEDEDERALRELQAEMGL
What is the function of this protein?
Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB).  Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity).
What are the official names of this protein?
Vacuolar-sorting protein SNF7, Vacuolar protein-sorting-associated protein 32.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: FAR12_LOBRE
Sequence: SPAFDDEHNDNFLRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-12, FMRFa-12.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYK_BAUCH
Sequence: MCKLNIFDPVQNYENLNQQLNLRRNKLNNLRKQGKTFTNNFKRNVISNQLFLQYGEKNNETLKTLNIQVSLAGRMINRRIMGKASFVILQDSGGTIQLYLSSKNLSDSFYNEHFKKWDLGDILGVHGRLFKTKTGELTINCNEIILLTKALRPIPNKFHGIVDKQIRYRQRYLDLITNKNSFNLFKTRSQIITEIRQFLNKEDFIEVETPILQSLPGGATARPFITYHNALDMNLYLRIAPELYLKQLIIGGFEKIFEINRNFRNEGLSAHHNPEFTMMELYIAYADYHDVMLLTQNLLNTITNHVLGTNIIQYGNLKLDFSKNFVKMTMKEAICHYNKQILSKHLDDKMQAITCAKNIGIHIDQKWGLGRIQTEIFEKTTEKHLLQPTFITSYPIEVSPLARRNDNNPFFADRFELFIGGYEIGNGFSELNDYEDQANRLIEQATIKNSGDNESMFYDEDYIIALEHGLPPTAGLGIGIDRLVMLLTNSHFIRDVILFPTMRLKI
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_HYDCU
Sequence: MKLKNIVNYLKEVGIDVELKGDDSINVDQVSGLVEAQQNHISFLSDSKRIHELETTSAGVVLIHPKFESLTTTTCLLVENPYFAFAKVSQLLNPENFPAGIHASAVVDDSAKIAESAWIGENVVIGKRVTIGDNCYIGPGSVVLDDSVIGQKTRLVANVTVMHNCIIGEEGYLDPGCVIGGQGFGFANEQGEWHKIPQIGRVVIGDRVFVGVNANIHRGAINDTVIESNCIIDSLVHIAHNVSIGYGSAIASQVGFAGSTAVGKYCVFAGQAGINGHISIADKSYFAAKSGVTHTIKESGSYSGFPAIPTPEWQKNMVRSKGLNKMAQKIKHLEKELQELKSKLEND
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: ACYP_RHIME
Sequence: MTKDRRAALVRITGRVQGVCFRDWTREEAERLGLDGWVRNESDGSVTALIAGPDGAVSRMLDHFWKGPPGASVADVASEEASSAEAPAGFRITRG
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: KEFC_KLEP7
Sequence: MDSHTLIQALIYLGAAALIVPIAVRLGLGSVLGYLIAGCIIGPWALRLVTDAEAILHFAEIGVVLMLFVIGLELDPQRLWKLRASVFGGGALQMVACGVLIGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLTVSQMGRSAFAVLLFQDIAAIPLVAMIPLLAASGGATSLMAFALSALKVAAALALVVVLGRYLTRPLLRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLVTHPLRIVILLVGFLAIKMLMLWLIARPLGVPRAQRRWFAVLLGQGSEFAFVVFGAARMADVLDGEWAKALTLAVALSMAATPILLVLLTRLEKSSSGQARDADEIDEEQPRVIVAGFGRFGQIAGRLLLSSGVKMVILDHDPDHVDTLRKFDMKVFYGDATRVDLLESAGAEKAEVLINAIDDPHVSLELVARVKEHFPHLQIISRARDVDHYIQLRQAGVEAPERETFEAALKSGRMTLEALGLGAYEARERADLFRRFNLQMVEEMVAMAENDAASRVAVFKRTSDMLTGIINEDRHHLSLVQRHGWQGTEEGRHTGDIADEPENKPSA
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CP2E1_HUMAN
Sequence: MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLYNNFPSFLHYLPGSHRKVIKNVAEVKEYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDLSPIHIGFGCIPPRYKLCVIPRS
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids (PubMed:10553002, PubMed:18577768).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:10553002, PubMed:18577768).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids (PubMed:10553002, PubMed:18577768).  May be involved in the oxidative metabolism of xenobiotics (Probable).
What are the official names of this protein?
Cytochrome P450 2E1, 4-nitrophenol 2-hydroxylase, CYPIIE1, Cytochrome P450-J.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Note=Post-translationally targeted to mitochondria. TOMM70 is required for the translocation across the mitochondrial outer membrane. After translocation into the matrix, associates with the inner membrane as a membrane extrinsic protein.
Protein: COAD_SHESM
Sequence: MHTRAIYPGTFDPITNGHADLIERAAKLFKHVIIGIAANPSKQPRFTLEERVELVNRVTAHLDNVEVVGFSGLLVDFAKEQRASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEENSFISSTLVKEVALHGGDVSQFVHPEVASALAAKLNLAKA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.