PharMolix/UniProtQA huggingface dataset:
Protein: RNY_LACLA
Sequence: MDIISIVLLVLLVVLVVAFIFYAQNIKKNKQDAESLFNEAENKANEVMANAKREAESLKMEAEAFKKEARYTLREEEQKQRREIEDEFKQERQELKETEKRLKQREEILDRKDDTLTKKEENLDSKEENLVRKTDTLSKREEQLAHIEEKKRLELERISNLSTDDAREIILSETRDGLTKEMAQIIRQSEEKAQVEADKRAKNIISLAIQRVSSDSVAEQTVSVVNLPDDGMKGRIIGREGRNIRTFEALTGIDVIIDDTPEAVVLSGFDPIRREIARMTLEQLVQDGRIHPARIEELVEKNRKALDHKMREYGEQAAFEVGAHNLHPDLMKIMGRLHFRTSYGQNVLDHSVEVAHIAGNLAGEMGENVALAKRAGFLHDIGKALDHEVEGSHVEIGTELARKYKENPIVINTIASHHGDTEPLSNIAVLVAAADALSAARPGARRESIENYIKRLKDLEAISTSFEGVETAFALQAGREIRVMVKPEKLTDDQIVILARDVKNRIEDEMDYPGNIKITVIRETRAIDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: BIOD_CLOB1
Sequence: MARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSGAERRDGKLIAGDANYVYNIANIKGDPNDAVSYIFQQAVSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGGIVCPISTGKERIMLHNIIKIFKLPAIVVADAGLGTINSTILTLQYMKEKNISVKMILLNNYNHKDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y663_MYCPN
Sequence: MRYGFFDISQDFITIFCPKKTLKNCMFGLIGSRTQATLRQEKNQNFSFFVNEANEIAGFNFFDIKKSFRRGLISHHFTAGLNYPSLKLVKKISELLNYDLTPLAKKVPFVVCEVISAIPIPNTHLKRCKVNTGSNKSLDVVCGADNVRVGLKTVLVHVGGVLPDGTIIKKAKIAGYDSMGMLCSEKELNLKPKNQGIIEIKSHIKIGKSFLDVYLNNSEKFSAWVSTKKRVTGN
What are the official names of this protein?
Uncharacterized protein MG449 homolog.
Protein: GPMI_PROMT
Sequence: MSGSNPAVSINKKKVAPVVLAILDGWGYREEIEHNAVRQASTPVIDALWHAYPHTLIEASGADVGLPDEQMGNSEVGHLTIGAGRIIQQELVRISNTVKENKLIANPALNQFSQSLKKGGGTLHIMGLCSDGGVHSHIKHLCGLIEWAASKGLKNVSLHLFTDGRDTSAKSATKYINTIEAKIKATGVGEISSLCGRYWAMDRDNRWERTSKAYELLTDPRFAISKLSAAESINKSYQEGITDEFIEPVRLSSSFLKDGDGVVFFNFRPDRARQLVKALKLKDFDGFERKNKTDIDVLTFTQYESGLPVSVAFPPEPLNDLLGQVIADHGLNQYRTAETEKYPHVTYFLNGGIEKPLKGEVRHLVPSPRVATYDLQPEMSADELTESCIQAIDTGIYSLVVINFANPDMVGHSGIMKAAIKANEKVDSCIGKLLNSIGKLGGSLLITADHGNSEMMIGPDGQPWTAHTTNPVPVILIEGEKRKLSGYGNDIKLRESGGGLADLAPTLLHLLNLPKPKAMTGKTLIEPINLPKKPNLIPQPAY
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: IF2_ARTS2
Sequence: MAKVRVHELAKELGITSKDAVTKLQELGEFVRSASSTIEAPVVRKLRNAYPAAGASKSEAPAAAPKAPASPAATRPAPAPGPAAPKAPEPKAEAPAAASAPSAPAPAAPAPAAPAAAASAPSAPAPAAPSTGAKPGARPAPKAEAPAAPARSGGQGSAPRPGGPRPGNNPFATSQGMPRGRGGDNERPPRPGNNPFAPSQGMPRPGGSRTEGERPGGPRPAAGAGGPRPGAPRPGGTQGARPGAPRPAGAPGARPGAGGGNRPTPGMMPNRTERPAPAGAGRPGGGGRGPGRPGGAPGTGGAPGAGGGAPAGGGFGKGGRGRGGTQGAFGKGGAGRGKQRKSKRAKRQELEQMSAPSLGGVSVPRGDGNTVVRLRRGSSITDFADKIEANPAALVTVLFHLGEMATATQSLDEETFALLGEELGYKLQVVSPEDEERELLSGFDIDFDAELEAEGDEELEARPPVVTVMGHVDHGKTRLLDAIRNSDVVAGEHGGITQHIGAYQITTEHEGAERKITFIDTPGHEAFTAMRARGAKVTDIAILVVAADDGVMPQTVEALNHAQAANVPIVVAVNKIDKEGANPDKVRGQLTEYGLVPEEYGGDTMFVEVSARQNLNIDELLEAVLLTADAALDMRANPNKDARGIAIEANLDKGRGAVATVLVQSGTLHVGDTIVAGTAHGRVRAMFDDDGSVLTEAGPSRPVQVLGLSNVPRAGDTFFVTADERTARQIAEKREAADRNAALAKRRKRISLEDFDQAVAEGKIDTLNLILKGDVSGAVEALEDALLKIDVGEGVQLRVIHRGVGAITQNDVNLATVDSAVIIGFNVKPAERVAELADREGVDMRFYSVIYAAIDDIEMALKGMLKPEYEEVQLGTAEVREVFRSSKFGNIAGSIVRSGVIRRNSKARISRDGKIIGDNLTVETLKRFKDDATEVRTDFECGIGLGSYNDINEGDIIETFEMREKPRV
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAA_ECO8A
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_CITBB
Sequence: MPKMKTHRGAAKRFSKTGTGKIKMAHAFTSHILTSKTRKNKRNLRKGGIVAASDHKNISCLIPYK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: VPU_SIVMB
Sequence: MDIVQQVGLLVVLIIELVIVIVIWVKVYKLCKEDRRQKKIDRLIARIRERAEDSGNESDGDTEELQDLITEGDNLMHIGIRDNRNN
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: ATPE_TUPAK
Sequence: MSLQICILTPDRVFWNQEAEEIILPTNTGQMGVLTNHAPIITALDIGIMSIRTQKDWTSVALMGGFALVKQNQVTVLVNSAESKETINSSEAEQAFLEAKEQLEKALGQKEKVEANFAFKRARARYQLVS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SUCC_MYCA1
Sequence: MDLFEYQAKELFAKHNVPTTPGRVTDTAEGARDIAAEIGRPVMVKAQVKTGGRGKAGGVKYAATPEDAYTHAKNILGLDIKGHVVKKLLVSEASDIAEEYYISFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVDAVTGVDLATARSIAEKGHLPAEVLDAAAVTINKLWELFVAEDATLVEVNPLVRTPDNQILALDGKVTLDANADFRQPGHAAFEDRDATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDVILHDKQVKSVFVNVFGGITSCDAVANGIVTALNMLGDEANKPLVVRLDGNNVDQGRRILAEANHPLVIQAETMDSGADKAAELANK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: GMCH_MALSM
Sequence: MKGIVSWAVVSAALVLSATESLAFANVSSFEKRTTTGNGWDLDGKSYDYVIVGGGTAGLVLANRLSANQGTTVAVIEAGNSGYDDNDKFVVPDANLYNSAVNTQYDWQFHTSSQKHMNNRRASWPRGKVLGGSSAVNGLYYVRPSETEVNVWSKLAGGSGRWSWNSLLSGMKKSEHFRGPVKSVQNQLQIQYNAGSHGSNGPIGTTWPAVTYDPVERFIKTADSMSGAINNDPYNGNNHGTYVALSSIDKTNWQRSFSRNGYLDPISKRSNLHVLTGHTVTGIIFDRSGKNAQATGVHYAASSNEASHTVHANKEVIISGGAINSPQILQLSGIGDKNLLNGLGIDVVVDLPGVGENLQDHVSAGMSFKPKNKKDAGPTSVTGDAKADSYVNSAVSYTSLGKLFNNKDSILGKIQARAKQIADSHNVSPAVKQGQSKAYNALADTIFPSKVSPVEILGNVMFGSISIQAALQHPLSRGSIKITSKDPFAYPKINPNYFAENLDLVLLREGFKLIREMSQQSPLKDVIDFETVPGDKVQTNEDWENWIRSAAGTEYHPSSTCAMLPRGDGGVVDENLKVYGTSNLRVVDASVTPIAMSCHLESVVYGLAEVAADIILGN
What is the function of this protein?
The recombinant protein is not active with choline, glucose, myo-inositol, methanol, ethanol, 1-pentanol, benzyl alcohol, 2-phenylethanol, cholesterol or lauryl alcohol as substrates.  Binds membrane lipids including phosphatidylinositol (PtdIns)(4)-phosphate (P), PtdIns(4,5)P2, phosphatidic acid (PA), and to a lower extent PtdIns(3,4,5)P3, cardiolipin and 3-sulfogalactosyl ceramide (sulfatide).
What are the official names of this protein?
GMC oxidoreductase family protein Mala s 12.0101.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PNM6A_HUMAN
Sequence: MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQESLEAALRPMGHFTVLGKAFREEDNATAALVELDREVNYALVPREIPGTGGPWNVVFVPRCSGEEFLGLGRVFHFPEQEGQMVESVAGALGVGLRRVCWLRSIGQAVQPWVEAVRCQSLGVFSGRDQPAPGEESFEVWLDHTTEMLHVWQGVSERERRRRLLEGLRGTALQLVHALLAENPARTAQDCLAALAQVFGDNESQATIRVKCLTAQQQSGERLSAFVLRLEVLLQKAMEKEALARASADRVRLRQMLTRAHLTEPLDEALRKLRMAGRSPSFLEMLGLVRESEAWEASLARSVRAQTQEGAGARAGAQAVARASTKVEAVPGGPGREPEGLLQAGGQEAEELLQEGLKPVLEECDN
What are the official names of this protein?
Paraneoplastic antigen-like protein 6A.
What is the protein family that this protein belongs to?
Belongs to the PNMA family.
Protein: OCLP1_APIME
Sequence: MSKFILLVCILLLTTNIVSAASKCGRHGDSCVSSSDCCPGTWCHTYANRCQVRITEEELMKQREKILGRKGKDY
What is the function of this protein?
The impact of this protein on the neuronal activity of the honeybee brain is not known.  It does not affect apparent movement or hatching of blowfly larvae.  However, when injected into fish, it induces a strong reversible paralytic effect.  In addition, the presence of this small peptide in the hemolymph of adult drones together with its induction after bacterial infection suggests that this peptide exhibits antibacterial activity.  This peptide may act by inhibiting ion channels.
What are the official names of this protein?
Omega-conotoxin-like protein 1, OCLP1.
Protein: EFTU_VIBC1
Sequence: MSKEKFERVKPHVNVGTIGHVDHGKTTLTAAICTTLAKVYGGAARDFASIDNAPEERERGITIATSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGGILVVAATDGPMPQTREHILLGRQVGIPYIIVFMNKCDMVDDEELLELVEMEVRELLSEYDFPGDDLPVIQGSALGALNGEEQWEAKIVELAEALDSYIPEPERAVDMPFLMPIEDVFSIQGRGTVVTGRIERGILNVGDEVAIVGIKDTTTTTCTGVEMFRKLLDEGRAGENVGALLRGTKRDEVERGQVLAKPGSITPHTKFESEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGDISLPEGVEMVMPGDNIQMQVELIAPIAMDEGLRFAIREGGRTVGAGVVAKIFD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLX_ECOLI
Sequence: MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENKPNRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSVSLQVRMPIVDWRRLCKQEPALIDYLI
What is the function of this protein?
GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.  In vitro, also exhibits ATPase activity.
What are the official names of this protein?
GTPase HflX, GTP-binding protein HflX.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
Protein: NDHI_HOFFA
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFIITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYHRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: TPIS_BORDL
Sequence: MRKVFLAGNWKMHYTSVEAADVAKQIVDGVYNINNNVVVMVTPTFTSLCKVCRVTKGTNVLLGAQNMSYENSGARTSEIAPSMLLEFGVDYVILGHSECRTYLGENDEIINKKVLTGLKHPFKYLILCVGETLEEREKGKTLDVVLNQVRNGLASVYESDLQRIILAYEPVWAIGTGKTATKEEAQEVHKAIRLEIQSLYSKSAADNIIIQYGGSVNVDNVEGLMGENDIDGALIGGASLKADSFLKIINKISK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNN_BURMS
Sequence: MSAERLVYVMGPSGAGKDSLLAYARKHVREPRIAFAHRYITRKSDGHENHVELTRDEFAARAQLGFFALEWSSHGFRYGVGVEIDAWLAAGSVVVVSGSRAHLPAALERYPQMCVVHIDAAPHVLAERLATRGRETADEIRARLARSVRWAVPDGIALTAIDNSGTLDDAGRVLVALLEGLARS
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: NIFB_RHILE
Sequence: MPGGRASSSYGLSVTDDKDARIWERIKDHPCFSEQAHHYFARMHVAVAPACNIQCNYCNRKYDCTNESRPGVASVKLTPDQALRKVLAVASKVPELSVIGVAGPGDACYDWRKTAATFEGVAREIPDIKLCISTNGLALPDHVDELADMNVDHVTITINMVD
What is the function of this protein?
Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms.  NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.
What are the official names of this protein?
FeMo cofactor biosynthesis protein NifB, Nitrogenase cofactor maturase NifB, Radical SAM assemblase NifB.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. NifB family.
Protein: NAPD_ECOLI
Sequence: MHTNWQVCSLVVQAKSERISDISTQLNAFPGCEVAVSDAPSGQLIVVVEAEDSETLIQTIESVRNVEGVLAVSLVYHQQEEQGEETP
What is the function of this protein?
Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase.  It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export (PubMed:17901208, PubMed:22329966).  May have a role in the insertion of the NapA molybdenum cofactor (PubMed:24314029).
What are the official names of this protein?
Chaperone NapD, NapA signal peptide-binding chaperone NapD.
What is the protein family that this protein belongs to?
Belongs to the NapD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPP2B_HUMAN
Sequence: MAASTASHRPIKGILKNKTSTTSSMVASAEQPRRSVDEELSKKSQKWDEINILATYHPADKGYGLMKIDEPSPPYHSMMGDDEDACRDTETTEAMAPDILAKKLAAAEGLEPKYRIQEQESSGEEDSDLSPEEREKKRQFEMRRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETADGESMNTEESNQGSTPSDQQQNKLRSS
What is the function of this protein?
Inhibitor of protein-phosphatase 1.
What are the official names of this protein?
Protein phosphatase inhibitor 2 family member B, PPP1R2 family member B, Protein phosphatase 1, regulatory subunit 2 pseudogene 3, Protein phosphatase inhibitor 2-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the protein phosphatase inhibitor 2 family.
Protein: WZYE_ECOSE
Sequence: MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPRRPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACSL4_HUMAN
Sequence: MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK
What is the function of this protein?
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590).  Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590).  Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET.  Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity).  Modulates prostaglandin E2 secretion (PubMed:21242590).
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase 4, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 4, LACS 4.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Cell membrane.
Protein: FICD_DROER
Sequence: MGTEAEPPSPPSPPAQQQEQANPPVWNAQNQKPARLYRLVLFFIAGSLTAWMFHAFSSSNLAWKLRQLHHLPTAHYLQTRDEFALYSVEELNAFKEFYDKSVSDSVGASFTEAEQTSINEALVSLRMAQDMYLTGKDDKAARLFEHALALAPRHPEVLLRYGEFLEHNQRNIVLADQYYFQALTISPSNSEALANRQRTADVVQNLDQRRLESLDSKRDALSAIHESNAALRRAKKEAYFQHIYHSVGIEGNTMTLAQTRSILETRMAVDGKSIDEHNEILGMDLAMKYINASLVQKIEITIKDILELHRRVMGHVDPIEGGEFRRNQVYVGGHIPPGPGDLALLMQRFERWLNSEHISTLHPVNYAALAHYKLVHIHPFIDGNGRTSRLLMNTLLMRAGYPPVIIPKQQRSKYYHFLKLANEGDIRPFVRFIADCTEKTLDLYLWATSDLPQQIPMLIQTESEAGERLAQMQSPNVAQRSSILEFYESGSGALP
What is the function of this protein?
Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context (By similarity).  The side chain of Glu-250 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place (By similarity).  Acts as a key regulator of the unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of Hsc70-3/BiP.  In unstressed cells, acts as an adenylyltransferase by mediating AMPylation of Hsc70-3/BiP at 'Thr-518', thereby inactivating it.  In response to endoplasmic reticulum stress, acts as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from Hsc70-3/BiP at 'Thr-518', leading to restore HSPA5/BiP activity (By similarity).
What are the official names of this protein?
Protein adenylyltransferase Fic, De-AMPylase Fic.
What is the protein family that this protein belongs to?
Belongs to the fic family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein.
Protein: ATPF_TRIV2
Sequence: MGTFLLLMAEASAVGGELAEGGAEGGFGLNTNILDTNLINLAIIITVLFVFGRKVLGNTLKTRRENIETAIKNAEQRAADAAKQLKEAQQKLEQAQAEAERIKKSAQDNAQTAGQAILAQAAVDIERLQEAGAADLNAELDRAIAQLRQRVVALALQKVESELQGGIADDAQKILIDRSIAQLGGEV
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PDXH_VEREI
Sequence: MNLSIAELRKSYGRAELNEDAAHADPLQQFDQWLGQAIAAQLPEPNAMTLATVGSDLRPSTRIVLIKGYDERGIVWFTNYDSRKGRQIAGNPCAALQFHWVELERVVRIEGLVQKVSDQESDAYFDSRPLDSRIGAWASPQSQVIAGRGVLLANAARYGAQFMLKPPRPQHWGGYRLEPDLWEFWQGRKSRLHDRLRYRMAGGQWVRERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.