PharMolix/UniProtQA huggingface dataset:
Protein: RS6_CUPPJ
Sequence: MRHYEIVFIVHPDQSEQVPAMIERYKSLVTSQGGQVHRVEDWGRRQMAYMIQKLAKAHYVCVNIECGKETLAELEHAFKFNDAVLRHLIVQTKKAETAPSPMMKEVQREEARKAAQTTTEGQAA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: EFGM_DROER
Sequence: MSLITRLLTGNNHLRIRALESLGKAGYSSHAKFSEHKPIERIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAATYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKAIYFEGEHGMDIRLDEIPQDMRVESLERRQELIEHLSNADETLGELFLEEKPFTEDDIKAALRRTCINRTFTPVLVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFIEKEGQDPEKIVLNPARDGKDPFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSNQMEDVNEVYAGDIFALFGVDCASGDTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARIIGIMEPLPPTQNTLLEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQDGGHHIVDSSELAFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQYQESQGLAQPDKKKKKN
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.  Essential during development as it acts as a retrograde signal from mitochondria to the nucleus to slow down cell proliferation if mitochondrial energy output is low (By similarity).
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YNFR_ECOLI
Sequence: MKAPSGAFLLGVYSMDTHILR
What are the official names of this protein?
Protein YnfR.
Protein: NDPA_MANSM
Sequence: MSITVNQIVLHQIIKPASANIPANNNNETENGETATQNTQLETVLRQELLPITAEAEQFMLELHQAYQNKTKGYGVFQEQSRFAQSLNRLLERETDFLPFSYEAAKLLSSELAKYAFAESGTFVLCRYNFLATDYLFIALLDSKASVLVDEKLEIHRTQYLNINQFDIAARINLTDLRVNANSNRYLTFIKGRVGRKIGDFFMDFLGADEGLNPQVQNQCLLQAVSDYCQKGELSAEQSQAVKKQVFDYCKGQINAGDEIELTELSETIPTLNQQPFADFAAEQDYGLENNIPPVRSALKSLTKFSGSGKGVTISFDAELLDKRIYWDDMQDTLTIHGLPANLKDQLQRLLKNHN
What are the official names of this protein?
Nucleoid-associated protein MS1911.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: KN4C_ORYSJ
Sequence: MEGSEAAQQKDSVKVVVNIRPLITPELLLGCTDCVTVTPGEPQVQIGPHVFTYDHVFGSTGSPSSLIFEQCVHPLIDSLFRGYNATVLAYGQTGSGKTYTMGTNYTGEANCGGIIPQVMETIFKKADALKDGTEFLIRVSFIEIFKEEVFDLLDASHAALRLDSGSVAKATAPARVPIQIRETGNGGITLAGVTEAEVKTKEEMASFLARGSSSRATGSTNMNSQSSRSHAIFTISMDQKKTSSASDKLSNDDYDILSSKFHLVDLAGSERAKRTGADGLRLKEGIHINRGLLALGNVISALGDEKKRKEGAFVPYRDSKLTRLLQDSLGGNSKTAMIACISPADSNAEETINTLKYANRARNIQNKAVVWSFSLKINRDPVTAEMQKLRSQLEQLQTELLFSRSGSAALEELQLLQQKVSLLELKNSELNHELKERELSYEQLAQSALAAQLEKDQLMLKIESARNGKSWDDIENTDTDQDVEVMKRYILKIQQLESELTRQKFSSTCKNDLHDRFAMDKDLLLDDLGSGCEVGTPDASSAVNFRITPVPAGEADEEKERDHSSMQDKLDKELQELDKRLQQKEAEMKEFAKSDTSVLKQHYEKKLNEMEQEKKALQKEIEELRHALTNITSSTDESAQKLKENYLQKLNTLESQVSELKKKQEAQQQLIRQKQRSDEAAKRLQEDIHRIKSQKVQLQQKIKQESEQFRSWKAAREKEVLQLKKEGRRNEYEMHKLLALNQRQKMVLQRKTEEAAMATKRLKESLEAKKSTRDTYGSASGSGIQALMRAIDDELEVTVRAYELRSHYERQMQERAAISKEIAKLKECPQAMSPSARSSRISALENMLSSSSSAMVSMASQLSEAEERERAFNGKGRWNHVRSLPDAKNTMNYLFQLASSSRCQQLDKEVMCKEKEHLICDLKEKVVALNGRIRQLETQVKDLNNQNMLLFTAISEAKNPVGTSRKGTVGSEDGQHYAMRKSIRASHSLHYSKNSFLWSDDMDISDSEKSEGSDADWEASDADYGASDADWECSKKVRRRRQTVSSHLNPNPGSGTTQKSAKSEMASQEKSTSLDLAPQCCSCSKYSSCKTQKCECRASGSHCGGDCGCITSRCSNRVDMKEEKEGGGVVEVSSSDDVDDAKVQEIVKEGVMLLENSMSEKEAQETKSRKPLADIGNGVVKQTGAKPKQRKNWRKSTVQLVPSAPPLPPTAPQNTEPVPRNRDIPLRLPRAMSSPAVDSIPLTDRNAAKPDESMSSNKENVTAVRARSPARPRKNANEKENHLR
What is the function of this protein?
Microtubule-dependent motor protein involved in the control of the oriented deposition of cellulose microfibrils.
What are the official names of this protein?
Kinesin-like protein KIN-4C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-4 subfamily.
Protein: TRUB_RICAE
Sequence: MSNYWLNIYKPRGISSAQLVSIVKKILGKTKIGHAGTLDVEAEGILPFAVGEATKLIHLLIDARKTYIFTIKFGMQTNSGDCAGKVIATKDCIPSQEEAYAVCSKFIGNVTQIPPAFSALKVNGVRAYKLAREGKKVELKPRNITIYDLKCLNFDEKNATATYYTECSKGTYIRTLAEDLALSLQSLGFVIELRRTQVGIFKEENAIRIKSPDEITKNALEEKSIKIEAILDDILVLDATDSQAQQIKYGQKCLFNYEKDFRHLAKFAYREEFKGNTERSTTAYTLVREDASTGLTYKLPLEVEFGKMSVDLLWVRYKGTLLAIGSLNKSCFNSLRVFNLTQDFF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: Y449_MYCGE
Sequence: MFDISKDFVSIFYRKETLKNCMFGIIGSRSETTLRQQNDKDWSFFVNDANRITGFNFFNIKKSFKKFFLSHRFNEGLNYPSLKIMKRISELLGYDLISLANKVPFVVCEVVSVIPIANTHLKRCKVNTGLTKSLDIVCGANNVRVGMKTVLVQVGGVLPSGTVIKKTKIAGFDSVGMLCSEKELNLKQKNEGIIEINPKIKVGKPFIDVYLNKQHSKWVNTKKRVKLS
What are the official names of this protein?
Uncharacterized protein MG449.
Protein: U518_DROYA
Sequence: MWLRQSSGGGVASAGHGGPLRQRPIDAATDCDPRACYDSFCKHWQQAFEIIQHSAPPSHDDVLGVVSHLDYMVTLLLVELHHCNKVSLPAAEASGPPAAPCLEFLLSENLLDKLYEWACTTGRYANAVRLEQLKLYELLVSHSRHQLLCHEPFLRPLLKILASSQGEIFPPDLEKRLVILLNQLCVVLMQNVHLLDLFFFSAQTQVQEQILNGNVAPPKSGTTTNFIIFSLLIPYVHREGSLGHQARDALLLCMALSQKNSNIGTYIAQYSSICPLLVTGLGGLYSRLPNSIEISSIDWHRITPDDVTEIPELTLFMNALEFCNAVVQVAHEMIKQQLLDFMYQGFIVPVLGPAILQTLKGKHFQTNIDSQISAMSYLDLILRSITEPGLLRAFVRFLLDTEKFDGERILDALVERLNSPDANLCMVTMALFDTLLGLHCEDLMLELLLKFMLPGKHVPISHRHKINKIDPYLNSSEFFLDLSPDVMKRARDLARPKSVHEPVVSDLTPLPSLPSPVMSKTIGANWNYYGVHTGDSLYANIQAYLFEAHWRIAQCQRDCLKWANSYRYQKWPRHGQGRVHAHALELARQFFSEFGGGPIAANETSEKQLDSLQSIGESSGYESFKWRPADEESEATDTTLATTASEADLDHNSSSLSSVLGASSKREAWRTSNNNRNELILTDLEFSEDLFAQGTVSLGPFLNAIWGKLQTFTSNSLYVNLHLTGLITRLAWYPLPLIHSLLLRSDIAITSDTPSFHQVLRILKQQIDAELPVTEDSLEIIDVARSSLIDREFRLANARKGNEGSPMHHSQQQQMATNSGQQQGQLRSAYATLSAATPVQATPTSAYDPFKRSDNKRRSISKSITSMFSRKSASNTSTTPPNGSSASSGLSQIYAFFTGAASNLVGTNASTDGRGMSHAQTSAGTCETSLSTQPQAGAPRTGAIATSATASGSNSSIAGSTLTLSAQSNTTTHSASTLHGLDGGPSTGGFNSEPASLDSVASMGIIASTSGTERSRDLALCAVLMDEWLKELAAIAQEQSVVLVTEQGSL
What are the official names of this protein?
FHIP family protein GE18198.
What is the protein family that this protein belongs to?
Belongs to the FHIP family.
Protein: BN3D2_DANRE
Sequence: MEAHDAHVNSEESENPGAAPYGNFINYYTFNPPENRLSLIPEALLQNIGFTSGDGERVLMLDVGCNSGDLSVALYKHLLNKEACTSDSPRQELYMLGFDLDQDLILRAQTSNPFPQNIQFIPLDITDDTESRAVLQAFLGKFGCSRFHLSTCFAVTMWVHLNHGDAAFLSLLSRLASHSEYLLLEAQPWKCYRSAARRLRKLGRSDFDHFKALKIRGDMAAHAREHLEKQCSMELVQCFGNTSWDRSLLLFRRQ
What is the function of this protein?
O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His)), acting as a capping enzyme by protecting tRNA(His) from cleavage by DICER1.  Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing.  The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1.  Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.
What are the official names of this protein?
Pre-miRNA 5'-monophosphate methyltransferase, BCDIN3 domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_CHLT2
Sequence: MVKLVVGIGNPGRQYVWTRHNIGFLLLDSLASRFLGAFREAPRLYASFAKVEISSEAVVLMKPTTYVNLTGKAVLAAKKFFDVSMEDILVVADDINREFGFVRFRQDCGSGGHNGIKNTTQILQSNHYWQLRLGVGRPSYPGAEGVADYVLSSFSLNEKEKLNDFLEKGIEEILPWLGC
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLC1_BURMA
Sequence: MALPLSDPNAPEFTRRYVNLADPRLGAQALEASDDFFAPKERMLNPEPAVFIPGKYDDHGKWMDGWETRRKRTTGYDWCVVKLARPGVIKGVDIDTSHFTGNFPPAASIEAAHVPDGAPNEATKWVEIVPATTLQGNSHHYVEARDANAYTHLRVNLYPDGGIARLRVYGQPQLDWAGASRSALFDLAAMENGGYVVAANNQHFGLASNVLLPGRGVNMGDGWETRRRREPGNDWAIVALAQPGVIRKVEIDTAHFKGNYPDRCSIQAAYVQGGTDSSLVTQAMFWPVLLGEQKLQMDKQHAFEAELAALGPVTHVRLNIIPDGGVSRLRVWGTLDK
What are the official names of this protein?
Probable allantoicase 1, Allantoate amidinohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: TRMO_HUMAN
Sequence: MRGLEESGPRPTATPCGCVKPALETGNLLTEPVGYLESCFSAKNGTPRQPSICSYSRACLRIRKRIFNNPEHSLMGLEQFSHVWILFVFHKNGHLSCKAKVQPPRLNGAKTGVFSTRSPHRPNAIGLTLAKLEKVEGGAIYLSGIDMIHGTPVLDIKPYIAEYDSPQNVMEPLADFNLQNNQHTPNTVSQSDSKTDSCDQRQLSGCDEPQPHHSTKRKPKCPEDRTSEENYLTHSDTARIQQAFPMHREIAVDFGLESRRDQSSSVAEEQIGPYCPEKSFSEKGTDKKLERVEGAAVLQGSRAETQPMAPHCPAGRADGAPRSVVPAWVTEAPVATLEVRFTPHAEMDLGQLSSQDVGQASFKYFQSAEEAKRAIEAVLSADPRSVYRRKLCQDRLFYFTVDIAHVTCWFGDGFAEVLRIKPASEPVHMTGPVGSLVSLGS
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU) (PubMed:25063302).  The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding ability (By similarity).
What are the official names of this protein?
tRNA (adenine(37)-N6)-methyltransferase, tRNA methyltransferase O.
What is the protein family that this protein belongs to?
Belongs to the tRNA methyltransferase O family.
Protein: SODM_LISIV
Sequence: MTYELPKLPYTYDALEPNFDKETMEIHYTKHHNIYVTKLNEAVSGHAELASKPGEELVANLDSVPEEIRGAVRNHGGGHANHTLFWSSLSPNGGGAPTGNLKAAIESEFGTFDEFKEKFNAAAAARFGSGWAWLVVNNGKLEIVSTANQDSPLSEGKTPVLGLDVWEHAYYLKFQNRRPEYIDTFWNVINWDERNKRFDAAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: SYL_TRIV2
Sequence: MDSRYNPAILEEKWQKTWVELGLDKTQTQSNKPKFYALSMFPYPSGSLHMGHVRNYTITDVIARLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPANWTYQNITQMRQQLQRLGLSIDWDSEVATCSPDYYKWTQWIFLQFLQAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWRSGAIVERKLLRQWFLKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSVGAYLEFPIVGSTEKIAVYTTRPDTVYGVSYVVLAPEHPLTKQVTSKTQQAVVDTFIQEVTNQSELERTAEDKPKRGVATGGKAINPFTGEEVPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAQRYDLPIDFVIAAPDDVAGFDLSPTSETEEVTQVVQIEYNQAYTEPGILINSGAFTGMTSTDAKQAIVKYATEKGFGKERIQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDKDLPVILPEEVEFTGRGGSPLAQLESWVNVPCPTCGSPAKRETDTMDTFIDSSWYFLRFTDARNEAQVFESAKTNDWMPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLLNFDEPFERLLTQGMVQGLTYFNPNKGGKDKWVPSHLVNPNDPRDPQTGEPLQRLYATMSKSKGNGVAPEDVIAKYGVDTARMFILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTDYVASGVNPKNKSGELSKSEKDLRRAIHSAIQSVTEDLEDEYQFNTAISELMKLSNALTDANGKDSRVYAEGIHTLVVLLAPFAPHIAEELWQLLGNSESVHTQTWPAFDPAALVADEITLVIQVNGKKRADIQVPSQADKAELEKYARESEVVQRHLEGKEIKKVIVVPGKLVNFVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_POLNA
Sequence: MKQVLLKAWRARGWLARLLWPVAQLHGLLVRLRRALYRRGMLSSERFKVPVIVVGNVVAGGAGKTPLVMALVKHFQAQGLRVGVVSRGYGRSGHESLEVRPGTPVDESGDEPALIQHATGAPVFVAQRRTQALRDLLAAYPATAVVVCDDGLQHYALQRDIEIAVFDDRGVGNGWLLPAGPLREPWPERLRQGVDLVLHTGQQPAFEGYTSRRQLADHAVAADGSSLALTALAHQPVVALAGIASPEAFFDMLRARGLTLQKTLALPDHHDFKTGDLNALAGRTVLCTEKDAVKLFALPDHSKIKLLAVPLEFSPEPAFFTALDGLLTPLLSQLPSSHGHQTT
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: FTSK_RICTY
Sequence: MILYYINKILSNNKVQAFILWIIGLAIVIVLISYNIDDPSFNSVTTEYPSNLIGIAGAYLSDFLYQFFGLTAFIIPLACFVWGRNCWHERYRSVFIRIFVVLLALISSSTLLSKIKLEFIPASAGGAVGIIVSNFCERFINQLYLLFQTFVILVVLLEIKLISISNVLIKLSKFLTNLILSFFNYIFPRLSLITIQNNDKLNITSFYQKPASKKVTFTEEASLIPTNPIKCFIKPVCTKISQNKIAALPPISLLCDPKNNHVKGASSSELKQKAEELLTVLNDFGVKGHIININQGPVVTQYEFEPAAGTKTSRVVGLSDDIARSLSALSTRIAVIPGKNVLGIELPNKQREFFCLKELIETPEYQDKSILLPLVLGKDLAGKPLIADLARMPHLLVAGTTGSGKSVGINAMIVSLLYRYTPEECRFIMIDPKMLELSAYDGIPHLLTPVVTEPSKAVIALKWAVKEMENRYRMMSNIGVKNIAGYNEKILEAVKENRVIERPIQTGFDPETGKPIYETVTMNMAKLPYIVVIVDEMADLMLVSGKDIEMLIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPSRISFKVTSKIDSRTILGEQGSEQLLGMGDMLFMGNTSKISRVHGPFVNEAEITKITEYLKETSMPVYISEVTEQPEENYSSIDIVDGSIDEVLYKKAVQIVRNERKASISYIQRSLRIGYNKAANLVEKMEKDGIVSPPNHTGKREILLPEM
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: FTSH_RUMCH
Sequence: MKYFKGISFYIIIFILILVIITFFTATDNPPKMSYSELLTEMKAGNVKSIGLQTDTATIELKKPKENNRTKFVVIVPPDVTSASERFTAALDNKLIEDFHVTQPPQPPWWVSMLPTVGLVIILILIWFFFIQQSQGGGGGNRVMSFGKSRAKMTVDDKKKITFENVAGADEEKEELAEIVEFLKAPKKFVELGARIPKGVLLVGPPGTGKTLLAKAVSGEAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKNAPCIVFIDEIDAVGRHRGAGLGGGHDEREQTLNQLLVEMDGFGINEGVIILAATNRPDILDPALLRPGRFDRRVVVGLPDIKGREQILKVHSRGKPLADDVRLDDLARITPGFTGADIENLLNEAALLTARANKKKIGNEEIKEAAFKVMMGPEKKSRVMSEHDKKVTAYHEAGHAIAIKLVSSSQKVDRVSIIPAGMAGGYTASRPQEDKSYHTRSQLIEEIIIALGGRAAEEITMDEVSTGASSDLKKVNQIARNMVTKYGMSEKLGNMIFGNDNDEVFIGRDLAQARNYSDELAAIIDNEVKSIIDNAYQKTVSLLRENIVRLNKLAEVLLEKEKVEGAEFEEIFENAVLEGSSQTPQLEG
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: WTF9_ARATH
Sequence: MLSIRRHAKTVASSCTNLTQKRTYVDVYMKWKRDPYFDNIEHILRSSQLKSVVSLKNCIVQEPNRCIPISAISKKTRQFDVSTKIAHFLRKFPSIFEEFVGPEYNLPWFRLTPEATELDRQERVVYQTSADDLRDRLKKLILMSKDNVLPLSIVQGMKWYLGLPDDYLQFPDMNLDSSFRFVDMEDGVKGLAVDYNGGDKVLSVLQKNAMKKRRGEVSLEEIEFPLFPSKGCRLRVKIEDWLMEFQKLPYVSPYDDYSCLDPSSDIAEKRVVGFLHELLCLFVEHSAERKKLLCLKKHFGLPQKVHKAFERHPQIFYLSMKNKTCTAILREPYRDKASVETHPVLGVRKKYIQLMKNSELILKSRRNSFGFRDEGVVDKDLDLDFEG
What is the function of this protein?
RNA-binding protein involved in group II intron splicing.  Binds specific group II introns and promotes their splicing (e. g.  rpl2 and ccmFC).
What are the official names of this protein?
Protein WHAT'S THIS FACTOR 9, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RNB_BUCA5
Sequence: MFQNNPLLTQLKKNLHAKSPRVEGIVKSTERGFGFLEVDPQKSYFIPPKNMKNVMHGDKIIALLTTEKDREIVEPEKLIEPFLNRFVGKIEKKDNRLFIVPDYPFLKDLITCQPNKNCINIFQNGDWAVAQLKKHKLKGDHLFYAELTEKITQEDDPLIPWWVTLARHDLDRKEPLAEEDDLILKESDNRKDLTDLDFITIDNTNTKDIDDALFVSEKNNGDISLIVAIADPTAYIKHGSKLDVIASKRIFTNYLPGFNIPMLPRNLSEDICSLNPNKRRPVLACHITVLKNGNISNKIEFFLAWIKSKSKLSYDHVSDWIEKIGSWIPPTKSIANQILILHRLCLLRIKWRKKNAVLFKDSIEYRFHVSEHGKIIDVLIEKRRIAHKIIEESMIVANISAANFLSKNIGFGIYNVHSGFDLVNAENAVSFLRSYNLNFTVKEITTLKGFCNLRRVLNIISNNYIDSRIRRFQSFGDFSTIPGPHFALGFSEYATWTSPIRKYSDMINHRLLKSIIKKEKSIKPGEDIKIKISEQRRRNRMAERDVSDWLYTIFLQKKKYQNQKFNAEITDISRSGIRARLIENGANVFIPGTLIHPIREELNFNQESGKVFINGIMHYKISDLIQVTLSDIRLKTRSIIAKPVFEKFK
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OX1R_HUMAN
Sequence: MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSVTTVLP
What is the function of this protein?
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide (PubMed:9491897, PubMed:26950369).  Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).
What are the official names of this protein?
Orexin/Hypocretin receptor type 1, Hypocretin receptor type 1, Orexin receptor type 1, Ox-1-R, Ox1-R, Ox1R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPQB_BIFLD
Sequence: MRRVTRTIAAAGAAIACCITMTACSSPFGLPISGSVQTLAPVEQQAQRVYTNPQGPADDAQPETIVKGFYDAMPAGVQSDGYRVAREFLTGSASAGWNGDSAALVYSGTPDFRRRANTISAPQGAESSLIVEVELQVVGSLDSHGVYTPSNSTQTRRLPYTLMKKSGQWRISSLESGVVISTADFEQVFRQVSVYQVSTSGKQLIPDIRWLSWRNWRTQAVGEVLSDAPSWLEGVLRGAGLSTIKLAVDSVPVKNNVVEIHLNSGINALNEEERGLLVHRIRLTMGDGNAEYALRITGDGVDYSDADANVKLTTEQPTAGVYTLTGGHIVSLASSSPLRVGEAPGYDDARGFVFSSSGGAVLRADGVVECLKSDGASCGVMFSGEPMRSITEGLDGEVWAVSENGRELHVSDGGKETDLKLDWLGAADSIVALAVSPEGCRLALAVEGEDTNGVMMTGVARNGDKTLSGLSKAATQVSVLRHVTMLTFYNDLNLVYATTPPEGNSEQQEAWRQMAPGPANAQRLPNGTITSMASGQISLSRRLAIVDDLGIVRSVSGSLDGSWTIADSQVTALGAQ
What are the official names of this protein?
Lipoprotein LpqB.
What is the protein family that this protein belongs to?
Belongs to the LpqB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: KATG_ASPNC
Sequence: MAEAKCPFSQSRSNANVAGGGTRNTDWWPDQLNLGILRQHAPASNPFERDFDYTAAFNSLDYYALKKDLHALMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRVFDGRGGGGQGQQRFAPLNSWPDNASLDKARRLLWPIKQKYGAKISWADLMLLAGNVALESMGFKTYGFSGGRADTWEADESVYWGGESTWMGNDVRYSDGFPGVTKHGALSGDEPPHRNIHTRDLEKPLAASHMGLIYVNPEGPDGNPDPVAAARDIRTTFGRMGMNDEETVALIAGGHSFGKTHGAASSENVDVEPAAAGLENQGLGWSNRYQSGKGPHTITSGIEVTWTKTPTKWSHAFLEYLFRFDWELTKSPGGANQWQAKNTEAIIPDAYDPSKKHLPKMLTTDLSLRYDPAYEKIARRFLDHPDEFADAFSRAWFKLLHRDMGPRTRYIGPEAPTEDLIWQDPIPAVNHTLVDANDIAALKRTILDTGLNKSNFVSTAWASASTFRGTDKRGGANGARIRLAPQRQWEVNNQPWLEETLSALEKIQKDFNDRVSSTGKKISLADLIVLAGCAAVEKAAQEAGQTITVPFTPGRMDASQEQTEVESFSHLEPVADGFRNYGKSSSRVRAEHYLVDKAHLLTLTAPEMTVLVGGLRVLNTNYDGSKHGVLTSSPGRLTNDFFTNVLDMNTAWKAKDGGRDLYEGTDRKTGQPKWTATRADLVFGSHAELRALAEVYGSSDGQEKFVKDFVSAWDKVMNLDRFDLKGSGIARSKL
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH602_CHLCV
Sequence: MSKIFKNRLEGLRALNRGVRALAKAVTSTLGPQGSHVVIKKDHSSPYVTKQGASIAKEIILPDAFENTGLKLIKEAALQMEAQVGDGSTTAIVLTDALFASGLKGVAVGLDPLEIKQGIQLAGAMLDEELAKLVVKISESEDIFHIATSSANHDAAIGKILADAIAQIGIEGVLSIKEGRGTETTLQATRHVGLNSGYLSSYFVTHPETMEVIYEDASILLCNQALSCLNQSFIHFLEQTFQTNRKPLIIIAEDFDPELLSILIVNKLKGNLPVCAIKAPGYGQQCKETLEDIAILTGATLVGDLLGISLSESSLDVLGRVEKIIVKRNTTIFSGGKGNQESLEQRIDYLRQAIVQSSSEMDTQDLEKRLARFVGGVAQIYLGSATENEYKERKIRLESALKAVKAAFKEGCLPGGGVALARAASIIKIPNELPIGVMFGCKCMLQSAEEPLRVLATNCGKDPEYVVDTVLKHADPYFGYNCINDSFENLITSGVFDPFSVTKCALKYSISISCLLLTSSFFIVDSSEKMQNPPLF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APN1_SCHPO
Sequence: MCAINKAYLLTKFYISANSCAFFVKSQRKWTSPDLSEDVAQKFLETASEMKFDASKQVLVHGSYLINMANADEQKREQAFNCFVDDLKRCERLGVGLYNFHPGSTASCTKEEGINNLAECINRAHEETKSVIIVTENMAGQGNCLGGTFDDFAALKSKIKNLDRWRVCLDTCHTFAAGYDIRTEESYKKVIDEFDEKVGAKYVSGWHLNDSKAPLGSNRDLHENIGLGFLGLEPFRLIMNDSRWDGIPLVLETPAKSPEQWKKEVELLRFMVGKSSDDVELMKESARLSNLGAASRKEHLNKFEKKEAKKDRKKKSKDGDQTTLLLRKKQKLGNAEVKSLDE
What is the function of this protein?
DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA.  Provides back-up AP endonuclease (APE) activity to apn2 together with uve1.
What are the official names of this protein?
Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYAY_CHLT3
Sequence: MTEKEIRIFLDETLEDIQDKLDAMDDDELDFETSDGLVSIETEDGTKYIVSRQSATNQIWLAEPINGWKFNLQDGKWISDKENHELYSFLEALLSQKLGKPIRLK
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.