PharMolix/UniProtQA huggingface dataset:
Protein: QUEC1_RHOP2
Sequence: MTEPVSDQTALVLFSGGQDSATCLAWALSRFARVEMIGFDYGQRHAVELDCRAKLLDGFRAISSEWASKLGDSHTLAIPTLSAISDTALTRDVEIAMGADGLPNTFVPGRNLIFLTFAAALAYRRGIADIVGGMCETDYSGYPDCRDDTIKALQGAISLGMARDFELHTPLMWRDKAATWQLAHDLGGAALVDLIREHSHTCYLGERGERHDWGYGCGECPACALRARGWREYRTRTG
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase 1, 7-cyano-7-carbaguanine synthase 1, PreQ(0) synthase 1, Queuosine biosynthesis protein QueC 1.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: HYFG_ECOLI
Sequence: MNVNSSSNRGEAILAALKTQFPGAVLDEERQTPEQVTITVKINLLPDVVQYLYYQHDGWLPVLFGNDERTLNGHYAVYYALSMEGAEKCWIVVKALVDADSREFPSVTPRVPAAVWGEREIRDMYGLIPVGLPDQRRLVLPDDWPEDMHPLRKDAMDYRLRPEPTTDSETYPFINEGNSDARVIPVGPLHITSDEPGHFRLFVDGEQIVDADYRLFYVHRGMEKLAETRMGYNEVTFLSDRVCGICGFAHSVAYTNSVENALGIEVPQRAHTIRSILLEVERLHSHLLNLGLSCHFVGFDTGFMQFFRVREKSMTMAELLIGSRKTYGLNLIGGVRRDILKEQRLQTLKLVREMRADVSELVEMLLATPNMEQRTQGIGILDRQIARDLRFDHPYADYGNIPKTLFTFTGGDVFSRVMVRVKETFDSLAMLEFALDNMPDTPLLTEGFSYKPHAFALGFVEAPRGEDVHWSMLGDNQKLFRWRCRAATYANWPVLRYMLRGNTVSDAPLIIGSLDPCYSCTDRVTLVDVRKRQSKTVPYKEIERYGIDRNRSPLK
What is the function of this protein?
Possible component of hydrogenase 4.
What are the official names of this protein?
Hydrogenase-4 component G.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
Protein: AAC6_ACIBA
Sequence: MNIMPISESQLSDWLALRCLLWPDHEDVHLQEMRQLITQAHRLQLLAYTDTQQAIAMLEASIRYEYVNGTQTSPVAFLEGIFVLPEYRRSGIATGLVQQVEIWAKQFACTEFASDAALDNQISHAMHQALGFHETERVVYFKKNIG
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring including amikacin, kanamycin, tobramycin and netilmicin.
What are the official names of this protein?
Aminoglycoside N(6')-acetyltransferase type 1, AAC(6')-Ih, Aminoglycoside resistance protein.
Protein: POLG_DEN1A
Sequence: MNNQRKKTGNPSFNMLKRARNRVSTGSQLAKRFSKGLLSGQGPMKLVMAFVAFLRFLAIPPTAGILKRWGSFKKNGAINVLRGFRKEISNMLNIMNRRRRSVTMILMLLPTALAFHLTTRGGEPTLIVSKQERGKSLLFKTSAGVNMCTLIAMDLGELCEDTMTYKCPRMTEAEPDDVDCWCNATDTWVTYGTCSQTGEHRRDKRSVALDPHVGLGLETRTETWMSSEGAWKQIQKVETWALRHPGFTVIGLFLAHAIGTSITQKGIIFILLMLVTPSMAMRCVGIGNRDFVEGLSGATWVDVVLEHGSCVTTMAKNKPTLDIELLKTEVTNPAVLRKLCIEAKISNTTTDSRCPTQGEATLVEEQDTNFVCRRTFVDRGWGNGCGLFGKGSLITCAKFKCVTKLEGKIVQYENLKYSVIVTVHTGDQHQVGNETTEHGTIATITPQAPTSEIQLTDYGALTLDCSPRTGLDFNRVVLLTMKKKSWLVHKQWFLDLPLPWTSGASTSQETWNRQDLLVTFKTAHAKKQEVVVLGSQEGAMHTALTGATEIQTSGTTTIFAGHLKCRLKMDKLTLKGVSYVMCTGSFKLEKEVAETQHGTVLVQVKYEGTDAPCKIPFSSQDEKGVTQNGRLITANPIVIDKEKPVNIEAEPPFGESYIVVGAGEKALKLSWFKKGSSIGKMFEATARGARRMAILGDTAWDFGSIGGVFTSVGKLIHQIFGTAYGVLFSGVSWTMKIGIGILLTWLGLNSRSTSLSMTCIAVGMVTLYLGVMVQADSGCVINWKGKELKCGS
What is the function of this protein?
Disrupts the host endothelial glycocalyx layer of host pulmonary microvascular endothelial cells, inducing degradation of sialic acid and shedding of heparan sulfate proteoglycans.  NS1 induces expression of sialidases, heparanase, and activates cathepsin L, which activates heparanase via enzymatic cleavage.  These effects are probably linked to the endothelial hyperpermeability observed in severe dengue disease.
What are the official names of this protein?
Genome polyprotein.
What are the subcellular locations of this protein?
[Capsid protein C]: Virion. Host nucleus. Host cytoplasm. Host cytoplasm, host perinuclear region. SUBCELLULAR LOCATION: [Peptide pr]: Secreted. SUBCELLULAR LOCATION: [Small envelope protein M]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Envelope protein E]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Non-structural protein 1]: Secreted. Host endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Note=Located in RE-derived vesicles hosting the replication complex.
Protein: HPE_HAEI3
Sequence: MKKIILTLSLGLLTACSAQIQKAEQNDMKLAPPTDVRSGYIRLVKNVNYYIDSESIWVDNQEPQIVHFDAVVNLDKGLYVYPEPKRYARSVRQYKILNCANYHLTQVRTDFYDEFWGQGLRAAPKKQKKHTLSLTPDTTLYNAAQIICANYGKAFSVDKK
What is the function of this protein?
Acts as a multifunctional adhesin involved in direct interactions with host epithelial cells and host proteins, including vitronectin, laminin and plasminogen.  In addition, interaction with serum vitronectin plays an important role in bacterial serum resistance, and conversion of plasminogen to plasmin at the cell surface aids in immune evasion and contributes to bacterial virulence.  Induces a pro-inflammatory epithelial cell response, leading to interleukin-8 (IL-8) secretion and up-regulation of ICAM1.
What are the official names of this protein?
Surface-adhesin protein E.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Cell surface.
Protein: MQO_LYSSC
Sequence: MSNRQIKSDVILIGAGIMSATLGTILKELAPDWKITVFEKLEKAGEESSHELNNAGTGHAALCELNYTSEKKDGSIDIKKAINVNEQFQVSRQFWSYLVNNKLINNPQDFIMPLPHMSLVQGKENVEFLKKRHETMIQNPLFEGMEFSNDPETLKKWIPLIMENRPAGEDIAATKIDTGTDVNFGALTRMLIDHLKAKDVDVNYNHSVESLKQASDGSWEVRVHDLDGCKMEYHSAKFVFLGAGGGSLELLQKSGIPEGKHIGGFPISGLFLACNNPEVAEQHHAKVYGKAKVGAPPMSVPHLDTRYIDNKKSLLFGPFAGFSPKFLKTGSNMDLFASVKPHNITTLLAAGVKEMGLTKYLIQQLMLSKEQRMEELREFIPNAKSDDWDIIVAGQRVQVIKDTEAGGKGTLQFGTEVVSAADGSIAALLGASPGASTAVHVMLEVINKCFPQHIKEWEAKIKEMIPSYGLSLAENPELLKEINATTDEALRLK
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: NSP5_ROTPC
Sequence: MSDFGINLDAICDNVKYKSSNSRTGSQVSNRSSRRMDFVDEEELSTYFNSKASVTQSDSCSNDLAVKTSIITEAVICDESEHVSADAIQEKEESIMQVDDNVMKWMMDSHDGISMNGGINFSRSKSKTGRSDFTESKSETSVSAHVSAGISSQLGMFNPIQNTVKKEAISEMFEDEDGDGCTCRNCPYREKYLKLRNKMKSVLVDMINEM
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: KBX33_OPICA
Sequence: MNNKLTALIFLGLLAIASCKWLNEKSIQNKIDEKIGKNFLGGMAKAVVHKLAKNEFMCVANVDMTKSCDTHCQKASGEKGYCHGTKCKCGVPLSY
What is the function of this protein?
Has antimicrobial activity against yeasts and bacteria.
What are the official names of this protein?
Opiscorpine-3.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 3 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_DESDA
Sequence: MSSIASVFGREILDSRGNPTVEVEVTLESGLRARAAVPSGASTGSREALEMRDGDKARYCGKGVTKAVDHVNSEIADALLGMDSLRQVQIDNTLIDLDGTDNKSRLGANAMLGVSMACARVAASFLGLPLYKYLGGINAKVLPAPMMNIINGGAHAPNNLDIQEFMIMPVGAMTFRDSLRMGTEIFHMLQAILKKDGHVTSVGDEGGFAPNLKNHDEAFAYIIKAIEEAGYNPGTEVALAIDAASSEFYKDGKYVLAGEGKTFNSAELSEWMAEFTRKYPLISIEDGMAESDWDGWGMLTASLGDHVQLVGDDVFVTNPSILAEGIAEGVANSILIKLNQIGTVTETLDTIEMAKEAAYTTVISHRSGETEDSFIADLAVGVNSGQIKTGSLCRSERMSKYNQLLRIEEELGDDAEFFGPMLAEYYSLGTEE
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RGS2_PIG
Sequence: MQSAMFLTVHHDCGPMDKSAGTGPKSEEKREKMKRTLLKDWKTRLSYFLQNSSSPGKPKTGKKSKPQTFIKPSPEEAQLWAEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCRKPPQITTEPHAT
What is the function of this protein?
Regulates G protein-coupled receptor signaling cascades.  Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (By similarity).  It is involved in the negative regulation of the angiotensin-activated signaling pathway (By similarity).  Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ.  Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity).  Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 2, RGS2.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus, nucleolus.
Protein: RCCDB_DICDI
Sequence: MYCWGSGRIGHGSPLSDIKTPKPLYFNISNSEQVNIFSEEEETEVKGEKDIEFIDFCAGRAHSLAIDNKNRCWVFGENSSAEFGNNSLVYSKVPILNKQFENEKIVSVSCWNQSYAITDQGKVWEWGKSIDTLIPRLLKFQYPIKAIDCSLNNSIGVSHNGIAFIGFNFNNEPKPVDYFIENNIEIQSVACGVNHYLYLTNRGEVYSNGGGISTGHYDEFYNNNNNNNNNNNNNNNNNNNNNNNNNNEIKEKVVEKVVEEEEGEEQFNIIIPKKLKQLRNIIEISSGYYNSLALDGYQNQVYGWGENLNGQLGIEGIDYSTEPILIELPLVEIKHISSGAYHSAFVTNNGELIVMGGGLVVSDDIRMSVALGNGEGGFQTIQFKVDTTKDETIISENIKFNKPTSQLINFEIKDKNENNETKHTNKNKDNHDDDDESDHSDDDHHDDDDNDKDSQGINDKGILTEEEMLEFQYHFNELSHYDGARNQFSPQFIQSLKKNKIVIDKVSCGKFHTLATPSKIQLIAPIESLQQYCIKYISENIINNMETDTSFPDINTLPINTVLKIDSHLTLNRNHSDRSQRLMSYLKSSFKQNINNNNNNNNSTTVNSPKSTKYEWDQYLENYSKEFEANAIVTLNNIEILTKTKGFEISLETINAIINGFIEFSQYIEQTSTQVANSENENENEIEMKMKMKKNEMKMKMKMK
What are the official names of this protein?
RCC1 domain-containing protein DDB_G0295713.
Protein: ESV1_MARPO
Sequence: MALDVLGRLGFFNCGSGSVVTPCSASARLSSELEPSKQRNRSWFRSPGSGGSTWAVANILCFDKDTIPESFRNGRLRSRARQKTLLEGASRSSLSSAARLWISKTAGIPSSRTGCRGSVLNGGWSGGEVAGEGRKSLLPIKRHSSCSSQSLPQQQRRTKDAGRVVCYSHRKRNLGSLLGSRVVEEPWSWILEGYVLKGLTGRRNDGPSELELGRGSYRGGPVHGANHIRPLQRPDSVHPQPLTSARPRRGTEHDELPLRRTLRNCIPHSRDTPPKRDTGIASEKDWGINLKNEKTSESGVNEDGSTWYRESGEDLGDNGYRCRWTVMGGKNADGTSEWKEAWWEKSDWTGYKELGAEKSGKNAQGDTWWETWQEILRQDDWSNLARIEKSAQKQAKSGSGTAGWYEKWWEKYNAKGWSEKGAHKYGRLNDQGWWEKWGEQYDGRGAVLKWTDKWAETDMGTKWGDKWEERFNVGIGTRQGETWHYSATGERWSRTWGEEHFGNGKVHKYGKSTSGESWDSVVEEGTFYQAEPHYGWADAVGNSGQLLSIVALERPPGIYPDLDLGMNKEQQ
What is the function of this protein?
Binds preferentially to highly ordered alpha-glucans, such as starch and crystalline maltodextrins (By similarity).  Involved in the organization of the starch granule matrix, thus influencing starch turnover by modulating the accessibility of starch polymers to modifying and degrading enzymes (PubMed:34367195).  Required for the control of starch degradation in leaves and starch distribution in nonphotosynthetic parts (PubMed:34367195).  Promotes gravitropic responses, negative in shoots but positive in roots, by facilitating starch granules (statoliths) formation in hypocotyls and roots columella (PubMed:34367195).
What are the official names of this protein?
Protein EARLY STARVATION 1, chloroplastic, MpESV1.
What is the protein family that this protein belongs to?
Belongs to the ESV1 family.
Protein: KGUA_STRP6
Sequence: MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALMREYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPB_BACC2
Sequence: MKNQDQALIFEVTKEGRVGYSLPKLDVEEVKLEDVFESDYIRVEDAELPEVSELDIMRHYTALSNRNHGVDSGFYPLGSCTMKYNPKINESVARFAGFANIHPLQDEKTVQGAMELMYDLQEHLIEITGMDTVTLQPAAGAHGEWTGLMLIRAYHEANGDFNRTKVIVPDSAHGTNPASATVAGFETITVKSNENGLVDLEDLKRVVNEETAALMLTNPNTLGLFEENILEMAEIVHNAGGKLYYDGANLNAVLSQARPGDMGFDVVHLNLHKTFTGPHGGGGPGSGPVGVKADLIPYLPKPILEKTENGYHFNYDRPEAIGRVKPFYGNFGINVRAYTYIRSMGPDGLRAVTEYAVLNANYMMRRLAPFYDLPFNRHCKHEFVLSGRRQKKLGVRTLDIAKRLLDFGYHPPTIYFPLNVEECIMIEPTETESKETLDGFIDKMIQIAKEVEENPEVVQEAPHTTVIKRLDETMAARKPVLRYAKPAPVQV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: CLPP_SPIOL
Sequence: MPIGVPKVPFRSPGEEDASWVDVYNRLYRERLLFLGQEVDSEISNQLIGLMVYLSIEDDTKDLYLFINSPGGWVIPGVAIYDTMQFVRPDVHTICMGLAASMGSFILVGGEITKRLAFPHARVMIHQPASSFYEAQTGEFLLEAEELLKLRETLTKVYGQRTGKPLWVVSEDMERDVFMSATEAQAHGIIDLVAVE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: VF137_ASFP4
Sequence: MEAVLTKLDQEEKRALQDFHRCAWEETKNVINDFLEIPEERCTYKFNPYTKKMELLFTPEFHTAWQEVPECREFILNFLRLISGHRVVLKGPTIVFTKEIKNLGIPSTINVDFQANIENMDDLQKGNLIGKMNIKES
What is the function of this protein?
Plays a role in the inhibition of the host innate immune response.  Mechanistically, promotes the autophagy-mediated lysosomal degradation of host TBK1 and affects IRF3 nuclear translocation to block type I IFN production.
What are the official names of this protein?
Structural protein A137R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus A137R family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: FTHS_STRT1
Sequence: MKTDIEIAQSVELKPITEVVEKVGIGFDDLELYGKYKAKLSFDKINEVKDDKPGKLILVTAINPTPAGEGKSTMSIGLADALNKIGKKTMIALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNALGIDQRRIIWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDINDLKERLANIVVAYRYDRTPVYVRDLEIEGALTLILKDAIKPNLVQTIYGTPALVHGGPFANIAHGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLDIKTPNLPTTPDAVVIVATLRALKMHGGVAKTDLSEENVQAVRDGFSNLKRHVENIRKFGIPVVVAINEFVADTEAEIAALKELCSEIKVPVELASVWANGADGGIDLANTVVDVVENGNADYKRLYSDDDSLEEKITKIVTEIYGGKSVVFEKKAKNQLKQFAEFGWDKLPVCMAKTQYSFSDNQFLLGAPEGFDITIREFVPKTGAGFIVALTGDVMTMPGLPKAPAALKMDVTEDGTAVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: ATPB_HELMI
Sequence: MNFGKVIQVIGPVVDIQFPPGQLPEIYNAIKIRSADQENYQGSFEIDITLEAAQHLGNNAVRCVAMSSTDGLMRGMKALDTGAPISVPVGAEILGRMFNVLGDPIDEAGQVAAKEVWPIHRKAPTFENLEPSTEVLETGIKVIDLLAPYAKGGKVGLFGGAGVGKTVLIQELINNIAMEYSGYSVFAGVGERTREGNDLYNEFKESGILKNVAMVFGQMNEPPGARMRVALSGLVMAEYFRDVQNQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLSTEMGQLQERITSTKNGSITSVQAIYVPADDLTDPAPATAFAHLDATTVLSRAIAELGIYPAVDPLDSTSRILDPHVVGDEHYSVARGVQKILQRYKELQDIIAILGMDELSEDDKIVVARARKIQRFLSQPFHVAEAFTGTPGKFVPLKESIRGFKEILEGKHDDLPESAFYMVGTIEEAVAKAKEMA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ARLY_MYCTA
Sequence: MSTNEGSLWGGRFAGGPSDALAALSKSTHFDWVLAPYDLTASRAHTMVLFRAGLLTEEQRDGLLAGLDSLAQDVADGSFGPLVTDEDVHAALERGLIDRVGPDLGGRLRAGRSRNDQVAALFRMWLRDAVRRVATGVLDVVGALAEQAAAHPSAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPYGSGALAGSSLGLDPDAIAADLGFSAAADNSVDATAARDFAAEAAFVFAMIAVDLSRLAEDIIVWSSTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGLVASLTFNVQRMAELAPAGYTLATDLAEWLVRQGVPFRSAHEAAGAAVRAAEQRGVGLQELTDDELAAISPELTPQVREVLTIEGSVSARDCRGGTAPGRVAEQLNAIGEAAERLRRQLVR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPCS3_DROME
Sequence: MHTVLTRGNATVAYTLSVLACLTFSCFLSTVFLDYRTDANINTVRVLVKNVPDYGASREKHDLGFVTFDLQTNLTGIFNWNVKQLFLYLTAEYQTPANQLNQVVLWDKIILRGDNAVLDFKNMNTKYYFWDDGNGLKDNRNVSLYLSWNIIPNAGLLPSVQATGKHLFKFPADYATSSI
What is the function of this protein?
(Microbial infection) Plays an important role in infection by flaviviruses such as West Nile virus and Dengue virus type 2.
What are the official names of this protein?
Signal peptidase complex subunit 3, Microsomal signal peptidase 22 kDa subunit, SPC22, SPase 22 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: ATP10_CANGA
Sequence: MRVVFQQCTKFSTSCNRAFLARFLKPVMNASPKEHVVKQLLKPVGLNVPPRPNIKYSEGNSWLDLFDGAKTEERIKELEIEFAKSGMYEMATFRKTNGKLFLSPESYWKADKALYFPHLSGRTLSSEDHGNVEDVLRGKTSVIRVFSTQVGDKISREYIKNTELGIDNYENQSCQVIDINFLENKLKSWLFKLSLNNLKSTVPVQRHDNYWLCHREQIPFLMRERLLINNVYSGYIFVVDPNLKIRFMACGPASADEFNKLWKVVGQLSKEKK
What is the function of this protein?
Involved in assembly of the mitochondrial F1-F0 complex.
What are the official names of this protein?
Mitochondrial ATPase complex subunit ATP10.
What is the protein family that this protein belongs to?
Belongs to the ATP10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: PPM1B_BOVIN
Sequence: MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITNNEDFRAAGKSGSALEPSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRSGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEFVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAMRKDSELDKYLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGNIIFFRRHVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEENPAEQAATAASSNSDAGNTVAMQESHTESKSDLAELDSCTEDAGTKMSGEKL
What is the function of this protein?
Enzyme with a broad specificity.  Dephosphorylates PRKAA1 and PRKAA2.  Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'.  Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB (By similarity).
What are the official names of this protein?
Protein phosphatase 1B, Protein phosphatase 2C isoform beta, PP2C-beta.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Lipid-anchor. Note=Weakly associates at the membrane and N-myristoylation mediates the membrane localization.
Protein: ATPA_PROMM
Sequence: MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGTEGIALNLEDDNVGAVLMGEGVGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKGDIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPIGRGQRELIIGDRQTGKTAIAIDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDPAALQYLAPYTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAMGSGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQKQLGRGKRLRELLKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEKVLNEDAETILKAAINEVKSSMLASA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: DHDH_DANRE
Sequence: MALRWGICSAGKISHDFTVALRTLPAEQHQVVAVAARELAHAQEFAQKHSIPRAYGSYEELAEDPEIDVVYVGTIHPHHLRVGLLFMNAKKNVLCEKPLAMNLKEVQQMISAARRSDVFLMEAVWTRFFPASLEISRLLSQNAVGQVKLVRADFGAALLGVPRAVQKHLGGGALLDIGIYCIQFVLMVFNGEKPEQIQASGVCLDTGVDEAMVVTLKFSGHRLAVCTCTVAAELPNEALIVGTEGTIKVPAHMWCPTSLLVNGVETQFPVPDPHLPLNFINSTGMRYEAEEVRRCVLAGLKESSRMSHADSALLADIMDEARRQVGVVYSQDSQ
What are the official names of this protein?
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, D-xylose 1-dehydrogenase, D-xylose-NADP dehydrogenase, Dimeric dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: PIMT_XANC8
Sequence: MTPRLRLQPESVGIGMTSQRVRDRLVERLRESGIQDEATLNAVRTVPRHLFIDEALASRAYEDTALPIGHGQTISQPWVVARMTEAVLQVAPKKVLEVGTGSGYQGAILAALGLEVYTVERIGDLLRQARKRFRHLGMNVRSKHDDGRIGWPEHGPYDAIVVTAAAPALVDALVDQLAVGGRLVAPVGGASSQSLVQLTRGADGEIAQEVLAPVTFVPLLSGMLD
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YG34_BPLLH
Sequence: MKPYLTTSDFEKLGYELKKPDNFGKLLKSATVLINQICSYYDPAFAYHDLEADSQADPDSYLFRQAMAFKKAVALEMLFLEDSGYSSAYDVAQGALNSFTVGHTSMSLNPSAGQNLTVGSTGVVKSAYDLLGRYGLLFSGVASL
What are the official names of this protein?
Uncharacterized protein ORF4.
What is the protein family that this protein belongs to?
Belongs to the Lactobacillus delbrueckii bacteriophages ORF4 protein family.
Protein: RL27_NOSP7
Sequence: MAHKKGTGSTRNGRDSNAQRLGVKRYGGQVVRAGNILVRQRGTKFHPGNNVGIGSDDTLFALIDGVVMFERKGKTRKKVSVYLPLTAVETAPAEAVAS
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RS2_THEFY
Sequence: MATVVTIRQLLESGVHFGHQTRRWNPKMKRFIFTERNGIYIIDLQKSLSYIDRAYEFVKETVAHGGTILFVGTKKQAQEAIYEQARRVGMPYVNQRWLGGMLTNFSTVHKRLQRLKELEEIDFDDVASSGLTKKELLGLRREKEKLERTLGGIRDMNRVPSAVWIVDTKKEHIAISEARKLNIPVVAILDTNCDPDEVDYPIPGNDDAIRSVSLLTRVVADAVAEGLMIRSGGAPGSEKGAGEPLAEWERELLEGKTEAAGEEATPAAEAPAKEEKAQAPEEKKEAGSGEEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.