PharMolix/UniProtQA huggingface dataset:
Protein: COX2_CANAL
Sequence: MIRLDVPTPWGIRLQDSATPNAEGIHELYDHIMFYLCLILGLVSYILYVIIKDYKDNRFAYKYVRHGQVIEIIWTIFPAVILLLIAFPSFILLYLCDEVLTPAMTIKVIGLQWYWKYEYSDFVDSIGETIEFESYVIPDDMLEPGALRLLDTDTSIVVPVDTHIRFVVTANDVIHSFTIPSLGMKIDATPGRLNQVSALIQRTGVYYGQCSELCGVNHGMMPIKLECVSIEDFIEWLGENEVSLNSSMVEQCTVNALILVQF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HEMH_CHLMU
Sequence: MTVYLLANFGGPRISQEIPSFLHALLTDQDVTGGRIPPWLHRPLFSYIAKRRAHRVAEQYAYLGGRSPIFQDTEKLAQNLSQELQAPVISFHRYLTETHQDTLAALRESAGDIIGIPLFPHYTFAVTGSIIRFFLERIPEKPMAWITHFGVHPQFISCMREHIQDCLIAQGIVAEDCFFLFSVHGLPMRHIRLGDPYAKQCQDSFNALIGESEGVLSFQSKFGIGEWLVPSTKEICQSLCTKKRYIVVVPFGFVSDHIETLYEIDHLYVPMLLQRGYRVVRVPAINTSDRWVSALASIVKSSPHETILEPLLMPKRR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIGA_DROME
Sequence: MQRVMPASWSSGGSLLPFRVSTTTKVVLFSLTAGVALMSVLSRFLRRRKPPRPPRRARKYTGRRNRNSMRSPNDLISIAGSKASARSGSPVGSTLAYSDRLSMASGSIGVGVLGVQNAGPGSSVVTQLTAQQLGMMGMEALDTVINFWEDALAAHYSPGGLPALLTTAEDSEFCREIQNLLEMAYTLQEQSELLFLDQRSVLFREEHSIDEAEEEAGEADDDRRSRKSGSVLSRAGSDPNFDSAESFASALDQVADLREFDGFIETSYEEYPLFQSALKHHDEYTVPCRTIRAELMHCSTDTEYLAKLHCVRLAFQFLFKDPAVGQWICDAGRQILTDLLCLGDKDTKEFLVGYEDMVNYLHDSNNWPCIQMELEQRNVKAMTFYDICLDFIILDSFKDLDAPPASVTAVVQNRWLSNGFKETALTTAVWSVLKAKKRMLKFPNGFMSHFYVISEQISPLMAWGFFGPNENLRDICHYFREELLAFLGDIFSFQKSRFTTIEEFSQDVLQHMQTRVNNIGVKFSQ
What is the function of this protein?
Regulator of mitochondrial fusion required to maintain neuronal homeostasis.
What are the official names of this protein?
Mitoguardin.
What is the protein family that this protein belongs to?
Belongs to the mitoguardin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: FLIT_ECOHS
Sequence: MNNAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVAPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNLF
What is the function of this protein?
Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD.  As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons.  As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SUCC_PHEZH
Sequence: MNIHEHQAKAVLAEFGVAVPRGYPAFSVDEAVQAAEKLGGPVFVVKSQIHAGGRGKGRFEGLGPDAKGGVRVVKSVDEVKANAEEMLGRVLVTHQTGAAGKQVNRLYIEEGAQIAKEFYLSLLVDRETSWVSVVASTEGGMDIEEVAHATPEKIVTFSIDPATGVFPHHGRHLAKALGLTGGLAKEAATLLNQLYAAFLAKDMSMLEINPLIVTGDDHLRVLDAKVSFDSNALFRHADVVALRDESEEDPKEIEASKYDLSYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPNVKGILVNIFGGIMRCDIIAEGVVAAVKEVGLKVPLVVRLEGTNVDLGKKIINESGLNVIAANDLSDGAEKIVKAVRGAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MURD_BURPS
Sequence: MFGDRQRPMVLVLGLGESGLAIARWCARHGCRLRVADTRETPPNLAALTAAGVDFEFVGGAFSPALVDGGIELVALSPGLSPLAEDLAPLVAAARERGIPVWGELEFFAQALAALGANGYAPKVIAITGTNGKTTTTSLAGLLCERAGKKVAVAGNISPAMLDKLTEAIDAAALPDVWVLELSSFQLDTAHTFAPDAATILNITQDHLDWHGGFAAYAAAKGRVFGPRTVRVLNRDDAEVMRFAPPAAAADAPRAVTFGLNEPAADGDYGLLRENGIAWLVEAIDRDGADAPAAPSRRRKQEAANPPDIALKRLMPADALRIRGLHNAANALAAYALARAIGLPAAPLLHGLREYRGEPHRVEVIATLDGVDYVDDSKGTNVGATVAALDGLAQRAVLIAGGDGKGQDFEPLAAPVARWCRAVMLIGRDAPALREALADTGVPLADHATLEAAVRAASALAQPGDAVLLSPACASLDMFRNYAHRADVFRSAVEDIALEKGTTL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPFC_GEOTN
Sequence: MAKKTVGLLVMAYGTPYKEDDIERYYTHIRHGRKPPQEQIDDLKARYRAIGGLSPLAKITEAQAKQLEKRLNEMQDEVEFCMYLGLKHIEPFIEDAVERMHADGVKEAVAIVLAPHYSTFSICSYNERAKAAAEKLGGPVIYTIDQWYDEPKFLQYWSEKVKAIFDAMKEREREQAVLIVSAHSLPEKIIQAGDPYPAQLEDTAKRIAEQAGVTHYAVGWQSAGNTPEPWLGPDVQDLTRQLHDEQGYTSFVYAPVGFVADHLEVLYDNDIECKQVTEEIGARYYRPEMPNTDPLFIDALATVVLKRLAKEGDEHE
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_UREPA
Sequence: MANVRPSVVFKQQEVNHMADILKNSKSFIVFEYHGLTAANILALRNVLHSSNSKLYVLKNNITARAFEKAGVSGFENQLTGPNAVAVAMDDEIAAIKAVNDVAKEFDFVKIKGAYLENKFADTHKIDQLAAIPGREGLYSMLLSCFTAPLRNVMYGLKAVAEQKGE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SYK_CAMJJ
Sequence: MFDNILEQQRIEKAKELKNLGINPYPHFLEKEMSLKTFKDKFSYILEQVEKRDESVNAVVAGRLKLLRIAGKSIFANIEDEDTNLQIYFSKDSVGEELYTILKKNLEVGDIVLVKGFPFVTKTGEFSLHASEVKLATKAIVPLPEKYHGLTDIEQRYRKRYVDMIMNVEVRKDFLVRSKVVSLIRHFFENKGFLEVETPMMHPIAGGANAKPFVTFHNSLGVERFLRIAPELYLKRLIVGGFEAVFEINRCFRNEGMDLTHNPEFTTIEFYWAYHNYKDLMDLTEELFALLLDKLNLGKTIEFDGKMINFSKPFERITYKDALCKYGGLDRDLIEDKEKILTKLKADGFEANEKLELGHLQAELFDNYVEEKLINPTFVIDFPISISPLSRRSDEDSQIAERFELFICGRELANGFNELNDPLDQYERFLKQIEAKNAGDEEACEMDEDFVNALGYGMPPTAGQGIGIDRLVMLLTNKKSIRDVILFPAMRPLKSELKEKE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_NITWN
Sequence: MNAPVKPSHLIKGATGEWEMVIGIEVHAQVTSNAKLFSGASTAFGGDPNSHVSLVDAAMPGMLPVINEECVRQAVRTGLGLNARINLRSVFDRKNYFYPDLPQGYQISQYKSPIVGEGEVVVDLADGTSFVVGIERLHLEQDAGKSLHDQHADMSAIDLNRSGVALMEIVSRPDMRSSEQARAYVTKLRTILRYLGTCDGDMEKGNLRADVNVSVRRPGEPFGTRCEIKNVNSIRFIGQAIEYEARRQIGILEDGGGIDQETRLFDPDKGETRAMRSKEEAHDYRYFPDPDLLPLEFSQGLVDALKADLPELPDQKKARFVTDLGLTSYDAAVLVSEHESANFYESVLADLADARRDGKAAANWVINELFGRLNKQGLSIEASPVSASQLAAIIDLIGEGTISGKIAKDLFEIVWSEGGDPRALVEARGMKQVTDVGAIEKVVDDIVAANPDKVAQVRAKPQMIGWFVGQVMKASGGKVNPQAVNDLLKAKLGL
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: SEP11_RAT
Sequence: MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVSNFQKKKAAAQLLQSQAQQSGAQQTKKDKDKKNPWLCTE
What is the function of this protein?
Filament-forming cytoskeletal GTPase.  May play a role in cytokinesis (Potential).  May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity.
What are the official names of this protein?
Septin-11.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Synapse. Cell projection, dendritic spine. Cell projection, axon. Note=Partly colocalizes with stress fibers. Association with microtubules not observed in embryonic fibroblasts. In cultured hippocampal neurons, localizes to 54% of GABAergic and 25% of glutamatergic synapses. Frequently present at the base of dendritic protrusions and at the bifurcation points of the dendritic branches. Expressed at low levels in the axons of mature cultured hippocampal neurons. In embryonic fibroblasts, associated with actin stress fibers.
Protein: GNAO_XENLA
Sequence: MGCTLSAEERAALERSKQIEKNLKEDGVTAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERRADAKMVCDVVSRMEDTEPYSPELLSAMVRLWADSGIQECFNRSREYQLNDSAKYYLDSLDRIGAPDYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWWHCFEDVTAIIFCVALTGYDQVLHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFQEKIKSSPLTICFPEYTGPNSFTEAVAHTQHQYESRNKSENKEIYTHITCATDTQNIQFVFDAVTDVIIAYNLRGCGLY
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The G(o) protein function is not clear.
What are the official names of this protein?
Guanine nucleotide-binding protein G(o) subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
Protein: PANB_THEP3
Sequence: MEEKVSTLTLRKFKKEGRKITALTAYDFPTAKILDNCGIDMILVGDSLGMVVLGYESTIPVTMEDMIHHTKAVSRAVNRAFIVADMPFMSYHISKEQAMTNAARLIAEGGAHAVKLEGGEEIASIVKAIVDAGIPVVGHLGLTPQSVHQLGGYKVQGKEKEQAKKIFNDAKVLEQAGICALVLESIPMELAKNITENISVPTIGIGAGPYCDGQILVTHDMLGITQGHRPKFVKQYADIEKIMIDGINAYIKEVQQVLFPDEEHSFTLEKRENK
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OP24A_ARATH
Sequence: MMKASFKGKFDVDKSGSVASLTFNAGNAKLRATMTDASFVAGPSFNGLSLAVEKPGFFIIDYNVPKKDVRFQFMNTIRIAEKPLNLTYIHMRGDNRTIVDGSFVIDPANKLSANYMVGTKNCKLKYTYVHGGIATFEPCYDVAKNMWDFAISHKLYGGDNLKATYQTSSKMLGLEWSNNSKSTGSFKVCASMNLAEELKPPKLTAETTWNLEL
What is the function of this protein?
High-conductance voltage-dependent solute channel with a slight selectivity for cations transporting triosephosphates, dicarboxylic acids, ATP, inorganic phosphate (Pi), sugars, and positively or negatively charged amino acids.
What are the official names of this protein?
Outer envelope pore protein 24A, chloroplastic, Chloroplastic outer envelope pore protein of 24 kDa A.
What is the protein family that this protein belongs to?
Belongs to the plastid outer envelope porin OEP24 (TC 1.B.28) family.
What are the subcellular locations of this protein?
Plastid, etioplast membrane; Multi- pass membrane protein. Plastid, chloroplast outer membrane; Multi-pass membrane protein. Note=Present in non-green root plastids.
Protein: RS10_CORA7
Sequence: MAGQKIRIRLKAYDHEAIDASAKKIVETVTRTGARVVGPVPLPTEKNVYAVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NODX_STRHE
Sequence: QLYDIGARAAFPSQPSPYGMTSQGQTNLPQQVQPQLVSETISSIKCIYIGQNDLTGYAGVIDGQTAGASACSDPQNYVKALAYGILGGTNLNSYK
What are the official names of this protein?
Nodulin.
Protein: EOBII_PETHY
Sequence: MDKKPCNSQDAEVRKGPWTMEEDLILINYIANHGEGVWNSLAKSAGLKRTGKSCRLRWLNYLRPDVRRGNITPEEQLLIMELHAKWGNRWSKIAKHLPGRTDNEIKNYWRTRIQKHIKQAETMNGQAASSEQNDHQEACTSQMSNGPNDNTIDQTYSPTSYSGNVDTFQAGPNFLTEANDNMWSMEDIWSMQLLNGD
What is the function of this protein?
MYB-type transcription factor controlling the production of volatile organic compounds (VOCs), including floral volatile benzenoids and phenylpropanoids (FVBP), in flowers of fragrant cultivars (e. g.  cv.  Mitchell and cv.  V26) by regulating the expression of ODO1 and EOBI, key regulators of the shikimate pathway, and of several biosynthetic floral scent-related genes including IGS, PAL2 and CFAT (PubMed:21585571, PubMed:20543029, PubMed:23275577).  This scent, mostly produced in the evening and night by the petals, attracts the pollinators (e. g.  the night-active hawkmoth pollinator Manduca sexta) (PubMed:21585571, PubMed:20543029).  Binds to and activates the ODO1 and EOBI promoters via MYB binding sites (MBS) 5'-AAACCTAAT-3' and 5'-CTAACT-3' (PubMed:21585571, PubMed:22499185, PubMed:20543029, PubMed:23275577).  Regulates the promoters of IGS1, CFAT and PAL2 (PubMed:20543029).  Controls flowers petal opening by modulating a global transcriptomic switch (PubMed:21464473).
What are the official names of this protein?
MYB-like transcription factor EOBII, MYB-like protein NON1, PhNON1, Protein EMISSION OF BENZENOIDS II, PhEOBII.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPE_SALG2
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGSVTVLADTAIRGQDLDEARALEAKRKAEEHIKSSHGDVDYAQASAELAKAIAKLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRAB1_ORYSJ
Sequence: MDLKDGGGSERRGAAAGAGAGAAPLARQGSIYSLTFDEFQSTLGGMGGGLGKDFGSMNMDELLRSIWTAEESQAMASASAAAAAAEGGLQRQGSLTLPRTLSVKTVDEVWRDLEREASPGAAAADGGGGGGEQQQPRRQPTLGEMTLEEFLVRAGVVRENTAAAAAMVAAAAAPPVAPRSIPAVNNSSIFFGNYGGVNDAAAAAAGAMGFSPVGIGDPTMGNRLMSGVAGIGGGAITVAPVDTSVGQMDSAGKGDGDLSSPMAPVPYPFEGVIRGRRSGGNVEKVVERRQRRMIKNRESAARSRARKQAYTMELEAEVQKLKEQNMELQKKQEEIMEMQKNFFPEMQKNQVLEAVNNPYGQKKRCLRRTLTGPW
What is the function of this protein?
Transcription activator that mediates abscisic acid (ABA) signaling.  Binds specifically to the ABA-responsive element (ABRE) of the EMP1 and RAB16A gene promoters.
What are the official names of this protein?
bZIP transcription factor TRAB1, Protein ABA RESPONSIVE ELEMENT 1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMM_NOCFA
Sequence: MGRLFGTDGVRGLANGSLSPELALRVSGAAAQVLGRGKTRALALVGRDPRASGEMLEAAVTAGLTAAGVNVLSVGVLPTPAVAYLTGLYDACLGVMISASHNPMPDNGIKIFAAGGHKLDDAVEDRIEALVAADDPVRPTGAGIGRVLNASGARDHGLHIPDQYSVEGTHERYVEHLVEATGRDLSGLTVVVDCANGAAAEVGPAAYREAGATVIAINAEPDGLNINDGCGSTHLDQVRRAVVEHGADLGLAHDGDADRCLAVAADGSVVDGDAILAVLAIAMKESGELAQDTLVATVMSNLGLHLAMRAAGIAVRTTAVGDRYVLEELRAGGYTLGGEQSGHVVFPKYGTTGDGVLTGLKLMARMAQTGRSLADLAGVLTTVPQVLVNVPVSDKAAVAAAPDVREAVADAERELGDSGRILLRPSGTEQLVRVMVEATDPVKAEQLAADLAKLVASL
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: NLEF_ECO57
Sequence: MLPTSGSSANLYSWMYVSGRGNPSTPESVSELNHNHFLSPELQDKLDVMVSIYSCARNNNELEEIFQELSAFVSGLMDKRNSVFEVRNENTDEVVGALRAGMTIEDRDSYIRDLFFLHSLKVKIEESRQGKEDSKCKVYNLLCPHHSSELYGDLRAMKCLVEGCSDDFNPFDIIRVPDLTYNKGSLQCG
What is the function of this protein?
Effector protein that alters host cell physiology and promotes bacterial survival in host tissues.  Inhibits the catalytic activity of human CASP4, CASP8 and CASP9, and thereby inhibits apoptosis of infected host cells.
What are the official names of this protein?
Effector protein NleF, Non-LEE-encoded type III effector F.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Injected into host cells via a type III secretion system.
Protein: ADAR_DROME
Sequence: MKFDSRVMLNSANNNSPQHPVSAPSDINMNGYNRKLPQKRGYEMPKYSDPKKKMCKERIPQPKNTVAMLNELRHGLIYKLESQTGPVHAPLFTISVEVDGQKYLGQGRSKKVARIEAAATALRSFIQFKDGAVLSPLKPAGNLDFTSDEHLENGIENLSSSKMFEIIQTMLTEKLSNPTSLEQPTFCMSQNVSKSAITVDGQKKVPDKGPVMLLYELFNDVNFECINIDGAQNNCRFKMTVTINEKKFDGTGPSKKTAKNAAAKAALASLCNISYSPMVVPQKNVPLPIDDKSSSMELPQIHADTIGRLVLEKFMEVIKGQEAYSRRKVLAGIVMTENMNFCEAKVISVSTGTKCVSGEHMSVNGAVLNDSHAEIVSRRCLLKYLYAQLDLQCNQATAYQSIFVRNTDGQYPYKLKSGVHFHLYINTAPCGDARIFSPHENDTGVDKHPNRKARGQLRTKIESGEGTIPVKSSDGIQTWDGVLQGQRLLTMSCSDKIARWNIVGIQGSLLSSIIEPVYLHSIVLGSLLHPEHMYRAVCGRIEKSIQGLPPPYHLNKPRLALVTSAEPRNQAKAPNFGINWTIGDTELEVVNSLTGRTIGGQVSRITKQAFFVKYGFLMANLPGILVRKVTTDYGQTKANVKDYQIAKLELFSAFKREDLGSWLKKPIEQDEFGLAE
What is the function of this protein?
Has A-to-I RNA editing activity on extended dsRNA: edits RNA-binding protein Rnp4F.  A-to-I editing of pre-mRNAs acts predominantly through nervous system targets to affect adult nervous system integrity, function and behavior.  Essential for adaptation to environmental stresses, such as oxygen deprivation, and for the prevention of premature neuronal degeneration, through the editing of ion channels as targets.
What are the official names of this protein?
Double-stranded RNA-specific editase Adar, Adenosine deaminase that act on RNA, Pre-mRNA adenosine deaminase, RNA-editing deaminase 1, RNA-editing enzyme 1, dADAR, dsRNA adenosine deaminase.
Protein: Y2319_MYCBO
Sequence: MAMEMAMMGLLGTVVGASAMGIGGIAKSIAEAYVPGVAAAKDRRQQMNVDLQARRYEAVRVWRSGLCSASNAYRQWEAGSRDTHAPNVVGDEWFEGLRPHLPTTGEAAKFRTAYEVRCDNPTLMVLSLEIGRIEKEWMVEASGRTPKHRG
What are the official names of this protein?
Uncharacterized protein Mb2319.
Protein: HLDE_SHEDO
Sequence: MKVTLPAFEKARVLVLGDVMLDRYWVGPTGRISPEAPVPVVKINQIEDRPGGAANVALNIATLGGQVQLAGLVGDDETAKALTLGVQTLGVEPQWLVVNDKPTITKLRVLSRNQQLIRLDFEEEFDSASSQALFKQSEAMLDNVDVLVLSDYAKGAIADPRAFIAKARAKGVTVLVDPKGSDFARYHGASLITPNMSEFEAVVGPVKDEADLIEKARQLIKTHEFSAMLVTRSEKGMTLITADEPELHIPTVAREVYDVTGAGDTVISALATSLGAGSTLAQACAIANTAAGVVVGKLGTSTVSRIELIGALASHQGESGFGVVSEDQLAYAMEQARLRGERVVMTNGCFDILHAGHVSYLKQAKALGDRLIVAVNSDASVKRLKGDGRPVNQVDRRMAVLAGLAAVDWVVPFCEDTPERIITRLLPDALVKGGDYKVEDIAGGAQVIAAGGKVEVLGFEDGVSTTSIIQNIMARQ
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: EFG_CYAP4
Sequence: MARTTPLERVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHEGNTVTDWMVQERERGITITAAAITTAWTKRDPQNPTQPMPGALEHKINIIDTPGHVDFTIEVERSMRVLDGVIAVFCSVGGVQPQSETVWRQANRYSVPRIVFVNKMDRTGANFYRVYDQIRDRLRANAVPIQLPIGAEDTLRGLIDLVRMRAYLYKNDIGTDIEETEIPADMQEQADEFRTKLVEAVAEADDVLMEKYLEGEDLTEEEIRAGLRQGTIAGTIVPMLCGSAFKNKGVQLLLDAVIDYLPAPTEVPAIQGTLPDGTEVERKADDAQPLAGLAFKIMSDPYGRLTFVRVYSGILKKGSYVLNSTKGKKERISRLIVLKADDRIEVDELRAGDLGAALGLKDTFTGDTLCDDSAPVILESLFIPEPVISVAVEPKTKQDMEKLSKALQSLSEEDPTFRVSVDPETNQTVIAGMGELHLEILVDRMLREFNVGANVGAPQVAYRETVRKPVRTEGKFIRQSGGKGQYGHVVIELEPGDPGSGFEFVSKIVGGVVPKEYIGPAEQGMKEACESGILAGYPVIDLKVTMVDGSFHEVDSSEMAFKIAGSMAIKDAVMKANPVLLEPMMKVEVEVPEDFLGSVMGDLISRRGQIEGQTATEGIAKVTAKVPLERMFGYATDIRSNTQGRGIFSMEFSHYEEVPRNVAEAIIAKNKGNA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSS_TULV
Sequence: MNSKLSLPGKNLKMQKRRWKPTRMMLTRAHYRVDGQLCQHWRTNWQTSRGSLQIWCQVKKWVKSLLTRLGLSRMITSRRDQAFDMEMSLM
What is the function of this protein?
Antagonizes host type-I IFN signaling pathway.
What are the official names of this protein?
Non-structural protein NS-S, NSs.
What is the protein family that this protein belongs to?
Belongs to the hantavirus NS-S protein family.
What are the subcellular locations of this protein?
Host cytoplasm, host perinuclear region. Host cytoplasm. Host nucleus.
Protein: CCSA_SORBI
Sequence: MLFATLEHILTHISFSTISIVITIHLITLLVRELRGLRDSSEKGMIATFFSITGFLVSRWVSSGHFPLSNLYESLIFLSWTLYILHTIPKIQNSKNDLSTITTPSTILTQGFATSGLLTEMHQSTILVPALQSQWLMMHVSMMLLSYATLLCGSLLSAALLIIRFRNSFDFFSLKKNVFLKTFFFSEIEYLYAKRSALKNTSFPVFPNYYKYQLTERLDSWSYRVISLGFTLLTVGILCGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHSRTNPNWKGTNSALVASIGFLIIWICYFGINLLGIGLHSYGSFTLPSK
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.