PharMolix/UniProtQA huggingface dataset:
Protein: CYCX_NITEU
Sequence: MTRLQKGSIGTLLTGALLGIVLVAVVFGGEAALSTEEFCTSCHSMTYPQAELKQSTHYGALGVNPGCKDCHIPQGIENFHLAVATHAIDGARELYLELVNDYSTLEKFNERRLEMAHDARMNLKKWDSITCRTCHKKPAPPGESAQAEHKKMETEGATCIDCHQNLVHEEVPMTDLNASIAQGKLVLKPEDDGDDEEADEDEDEETEEADDSSDSESASSSDNSDNEDDNNDE
What are the official names of this protein?
Probable tetraheme cytochrome c-type.
What is the protein family that this protein belongs to?
Belongs to the NapC/NirT/NrfH family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PLSX_DESHY
Sequence: MMRIAVDAMGGDHAPAEIVKGALRSIEQFDIEVILVGQPERIKEFLPQGEVPARVRIKEATEVVEMDEHPAQAVRRKKDSSIVVATRLVKEGEADALVSAGSTGAQMAASLLGLGRIKGIDRPAIVTVLPTLEGGKLLLDVGANPDAKPEHLVQYAMMGSIYAESILGIQNPKVGLLNIGTEETKGNELTQATYPLLQKAPLNFIGNVEGRAIPYGQAADVVVCEGFVGNVVLKTTEGLAGALFQLIKEKITATPLRKLGALAIKPGLKEIAKMMDYAEYGGAPLLGVHGISIISHGSSNEKAIFNAIRVAKECVESGFIEEIKKELPRFTAAQE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RTCA_METCA
Sequence: MTLLRIDGSYGEGGGQIIRTALSLAALTGTAVRLENIRARRRKPGLAAQHLTAVKAVALLCDARIGGAELGSQTLEFIPGRPVRAGDYTLDVGEAREGGSAGAVMLVLQTVLPPLALAEGASTVSLRGGTHVPMSPPFDYVREVWLPTLARMGVRAELSLVRSGWYPVGKGEVRLVVAGGRRSLEALKARHRGTLQAVTGRALAANLPAHIPERMAARARAVLADAGIAAAIEPAVLQAACAGAGLFLTARYDHCLAGFTALGRRGKSAERVAEEACGALLAHHRSGAALDQHLADQIVLPAALCREESLFSVERITPHLTTNAWVVDRFGLARVDVRLAECGTGLVRIHGNPAGVCHAHP
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_HAEIN
Sequence: MQEQYRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDREIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQVHEGCCWRCDTPVEQKEIPQWFIKITDYAEQLLGGLDTLPQWPDMVKTMQRNWIGRSEGVEITFDVANTNEKVAVYTTRPDTFYGVSYLGIAAAHPLASLAAQNNSELAAFIQEAKNAKVAEADLATMEKKGMATGLFAIHPLTGDKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYSLPIKQVIAPLADEEIDLTKQAFVEHGKLVNSDEFDGKNFDGAFNGIADKLEKLGVGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILPEDVVMDGVKSPINADPNWAKTTFNDAPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGFVTSEEPADKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLERDEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMTLEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDLTALSAEQKVLRREVHKTIAKVSDDIGRRQTFNTAIAAVMELMNKLTKASLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQALGNESAIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVATDADEDTVKTIAFADENVKKFIDNQHIVKVIYVVGKLLNVVVKP
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4EK_SINFN
Sequence: MHPMNRYEVALVTGASSGIGKAIALELASAGLRVLALGRDRAALDELHSTAGIVPVVFDLSDVSEVYGKIAGEKIDVLVNNAGLLTASASLVDLSEDDIDAMIDINIRSVFKLTRHVLKQMIERRRGHIFFTGSSGGLAPHPNSSVYGATKAAVSLFSSALRCDLIGLPIRVTELFPGRVETNLYRTALGKEGAKKKLYDDNEAIQPEHMARLLRTALELPDFVDVTRLEVMPTGQVVGGAQMSKLSR
What are the official names of this protein?
Uncharacterized short-chain type dehydrogenase/reductase y4eK.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: COAE_NEIGO
Sequence: MTAWVGLTGGIGSGKSAAAQYFADLRVPRIDADRAAHSLTASDGIALPEIRRLFGDTVFDTQGLLRRDILRKEIFASPSRKALLESVMLPLIFSEIKKQQETFTDAVYGIVEIPLLTEKRQFISLIRRVLTISAPLEKRIGRVMARSGLTRGEVADIISHQASESERLLLADDVLLNDGSLKSLREKTMLLHAFYSGIFASKPTQGKHNG
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_LACDA
Sequence: MLCPNCHQNASRVIDSRPTDEGRTIRRRRECENCGYRFTTFERVEQSPLLVIKNDGTREAFSREKILNGVAAACQKRPVTSEQLNKLVDNVENRIRAKGVSEIYSKEIGELVMDQLADIDDVAYIRFASIYRQFTDMSSFMKTMEDMMDRHSKAK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SCAM5_RAT
Sequence: MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHLSLTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFGTNIGSAVVMLIPTVMFTVVAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSTTPNYTYSNEM
What is the function of this protein?
Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5.  Probably acts in cooperation with the SNARE machinery (By similarity).
What are the official names of this protein?
Secretory carrier-associated membrane protein 5, Secretory carrier membrane protein 5.
What is the protein family that this protein belongs to?
Belongs to the SCAMP family. SCAMP5 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi- pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Mainly localizes in Golgi apparatus membrane. Upon calcium-triggered exocytosis, it translocates to the cell membrane. Highly enriched in synaptic vesicles (By similarity).
Protein: DNAJ_LACPL
Sequence: MAEQDLYKVLGVEKDASQDEIKKAYRKLSKKYHPDLNHEPGAEEKFKAVNEAYETLGDAQKRAQYDQFGSTGGQQGFGGAGGFGGQDFGGFGGGGGFEDIFSSFFGGGAGGSRRSNPTAPQQGRDLQYEMTLKFEDAIFGKKTTITYNREEQCETCGGSGAKPGTSPVTCSKCHGAGYIQVQTNTPLGRMMSQQVCDVCHGTGKEIKDKCATCGGSGHTEQSHSIKVTVPAGVEEGQQMRLQNQGEAGTNGGPYGDLFIIFRVEPSKDFERDGATIYFKLPIDFVQAALGDEVQVKTVHGDVKLKIPAGTQTGTTFRLRGKGAPRLRGNGNGDERVTVNIETPTHLNKGQKEALKTFAKASGKSVAGNGKSSLFDKLRGV
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3J_BOMMO
Sequence: MDVSWDADNFEPKLPTTLAASNKWEGEDEDDNVKESWEDEEEEKKDEEKTEAAPPPQPKPKKKIHDKIAERERQEREKAERLVTEKTAEEMTPEQKLAEKLRQQKLQEESDLRLAMETFGVTEGNIGKLDNFHPTTKEEYTEFADLLTKKITFYKAKDEFPGFIDDLVKNILVQMSSADIRRIKLTVDNLYIEKQKAEKNDKTKKATKGKGKAKLKLEGDNAHLNQYESYGNFDDDYDDFI
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit J, eIF3j.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit J family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THI4_SULIY
Sequence: MEVKIKQVDEVKISRYIIKETMEDWYQFVESDVVIVGAGPSGLSAAYYLAKAGLKTLVFERRLSFGGGIGGGAMLFHKLIIEKPADEILREVNVRLKEVEEGVYVVDSAEFMAKLATAAIDAGAKIIHGVTVDDVIFRENPLRVAGVAVEWTATQMASLHVDPIFISAKAVVDATGHDAEVISVAARKIPELGIVIPGEKSAYSERAEELTVINTGKVAEGLYAAGMAVTEVKGLPRMGPIFGAMVLSGKAVAEEITKDLLKSEIRT
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: KAD8_RAT
Sequence: MDATSAPHRIPPEMPQYGEDYHIFEMMQSMLEQLLIHQPEDPISFMISHLRRNNDNVPRVVILGPPASGKTTIAMWLCKHLNSNLITKENLLEREFSLLSLEAKKHYQVYKRVPNSTLVSLVQERLNEDDCLRRGWILDGIPERREQALMIQTLGLAPKHVIVLSAPDSVLIERNVGKRIDPVTGEIYHTTFDWPPELEIQNRLIQPEGISEIDTAKKLLEYHRHIIRILPSYPKILKTISSDQPCVDVFYQALTYVQSGHRCNAPFTPKVLLCGPMGCGKKLQAALLSQKYGLVNISCGQLLKEAMAAESSLGDLIEPFFEKRMTVPDSIITRVLTERLKQQDCIQKGWVLHGFPRDLDQARLLNSMGYSPNRVFFLNVPLDSILERLTLRRTDPVTGERFHLMYKPPPTIEVQARLLQNPKDSEEYIKLQTDLFYRNSGDLEQYYDRAIIVNGDQDPYTVFEYIESGIINPLPRKVT
What is the function of this protein?
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.  Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP.  Also displays broad nucleoside diphosphate kinase activity.
What are the official names of this protein?
Adenylate kinase 8, AK 8, ATP-AMP transphosphorylase 8.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, cilium axoneme. Note=Located in the proximal region of respiratory cilia.
Protein: DPO4_SHESA
Sequence: MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATGYALKLCPDLILVPGRMQVYKEVSQQIRAIFCRYTELIEPLSLDEAYLDVSDCKLFKGSATLIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNGQCVIPPDEVAEFVKSLSLRKIPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGTVLVERAHGIDERGISVSRERKSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLGRSAKGRQIHKQVVKLKFNDFKQTTIEHRSDEVSVVMFYELLSQAMARQEGRGIRLLGVSVGLAESKDTLSPLMVRETKQLDFVF
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_THESQ
Sequence: MIKKESKKEQRLRRHRRVRKKVFGTPERPRLCVFRSNKHIYAQIIDDTIGHTLVSASTLDPELREKLQKTWNVEAAKEVGLLIGKRALEKGIKKVVFDRGGYKYHGRVKALADGAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: QACR_STAAU
Sequence: MNLKDKILGVAKELFIKNGYNATTTGEIVKLSESSKGNLYYHFKTKENLFLEILNIEESKWQEQWKKEQIKCKTNREKFYLYNELSLTTEYYYPLQNAIIEFYTEYYKTNSINEKMNKLENKYIDAYHVIFKEGNLNGEWCINDVNAVSKIAANAVNGIVTFTHEQNINERIKLMNKFSQIFLNGLSK
What is the function of this protein?
Transcriptional repressor of qacA.  Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site.  QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA.
What are the official names of this protein?
HTH-type transcriptional regulator QacR.
Protein: Y4NM_SINFN
Sequence: MPGSPPPENAPAVLWTCFGASGWRMLLMKQRRNEMKVLDLDCFDRKLPLICDLDGTLIKSDSLHENLFDAFFHSPQQLLRTIPNWFKGRPALKEALAKVRSVEPQALPYREQMLDLIRRARSAGRETYLVTAADQSIADDIISHLGGFDGAKGSSGSLNLKSRRKLQWLQESFPEGFIYAGDSAADLPIWEAASGAVLVGDGVKFESKLREAGVEVRTLSPEKSHPVKDWLSELRIHQWSKNVLIFVPLFLGRIADDFHAVLKTTFGFLAFGLIVSATYIINDLADLEADRAHATKRFRAIAAGRISVMNGFLACLVMLATGIGTALLLDHQFALVASVYLALTLAYSFRLKRVALLDVTVIGALFTLRIVMGQVLNGLAFSPWLFSFSVMFFISLALAKRHVEAMRACSNRKDTIEGRGYLPGDWPLTLGHGLASASASIVIMLLFLALEPRVTHLYHNPAWLYVAPLGVSIWLQRIWLLSHRMELHDDPIVFALNDKTSWFIGALIASAFVMAM
What is the function of this protein?
Possible permease/transporter.
What are the official names of this protein?
Uncharacterized protein y4nM.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RK36_TUPAK
Sequence: MKVRPSVRKICENCRLIRRKRKILVICTNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYT_PSEFS
Sequence: MPTITLPDGSQRSFDHSVSVAEVAASIGAGLAKATVAGKVDGKLVDASDLITNDASLQIITPKDQEGLEIIRHSCAHLIGHAVKQLYPTAKMVIGPVIDEGFYYDIAYERPFTPDDMAAIEQRMHALIEKDYDVIKKVTPRAEVIDVFTARGEDYKLRLVEDMPDEQAMGLYYHEEYVDMCRGPHVPNTRFLKSFKLTKLSGAYWRGDAKNEQLQRIYGTAWADKKQLAAYIQRIEEAEKRDHRKIGKRLNLFHLQEEAPGMVFWHPNGWTLYQVLEQYMRKVQRENGYLEIKTPQVVDRSLWEKSGHWANYADNMFTTQSENRDYAIKPMNCPCHVQVFNQGLKSYRELPMRLAEFGACHRNEPSGALHGIMRVRGFTQDDAHIFCTEEQMQAESAAFIKLTMDVYRDFGFTEVEMKLSTRPEKRVGSDELWDRAEAALAAALDSAGLAYDLQPGEGAFYGPKIEFSLKDCLGRVWQCGTLQLDFNLPIRLGAEYVSEDNSRKHPVMLHRAILGSFERFVGILIEHYEGAFPAWLAPTQAVIMNITDKQADFAAEVEKTLNESGFRAKSDLRNEKIGFKIREHTLLKVPYLLVIGDREVEMQTVAVRTREGADLGSMPVAQFAEFLAQAVSRRGRPDSE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NART_STAA9
Sequence: MYKTKGGFQLTLQTLSLVVGFMAWSIIAPLMPFIKQDVNVTEGQISIILAIPVILGSVLRVPFGYLTNIVGAKWVFFTSFIVLLFPIFFLSQAQTPGMLMASGFFLGVGGAIFSVGVTSVPKYFPKEKVGLANGIYGMGNIGTAVSSFLAPPIAGIIGWQTTVRSYLIIIALFALIMFIFGDTQERKIKVPLMAQMKTLSKNYKLYYLSYWYFITFGAFVAFGIFLPNYLVNHFGIDKVDAGIRSGVFIALATFLRPIGGILGDKFNAVKVLMIDFVIMIIGAVILGISDHIALFTVGCLTISICAGIGNGLIFKLVPSYFSNEAGSANGIVSMMGGLGGFFPPLVITYVANLTGSSHLAFIFLAVFGCIALFTMRHLYQKEYGSLKHS
What is the function of this protein?
Probably required for nitrate uptake under anoxic conditions.  Also possibly involved in excretion of nitrite produced by the dissimilatory reduction of nitrate (By similarity).
What are the official names of this protein?
Probable nitrate transporter NarT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPF_BRUMB
Sequence: MALDIKICGLKTPEAVAAALDGGATHIGFIFFPKSPRHITPDAAARLRAAATGRAVAVAVTVDADDEALDEIVKTVRPDMLQLHGGETPERVRFLKERYNLPVMKAFSIREAGDLEAIAPYRGIADRFLFDAKPPKGSELPGGNGISFDWNLLAALDADIDYMLSGGLNADNIAEALLKTGAPGIDISSGVECAPGEKDVRLIENFFQAVADANAQPFARRA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RL19_STRSV
Sequence: MNPLIQSLTEGQLRTDIPAFRPGDTVRVHAKVVEGTRERIQIFEGVVIARKGAGISETYTVRKISNGIGVERTFPIHTPRVDKIEVVRYGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL38_TIMBA
Sequence: MPRELTEIKEFLLTARRKDAKSVKIKKNPENTKFKVRCSRFLYTLVITDREKAEKLKQSLPPGLQVKEVK
What are the official names of this protein?
60S ribosomal protein L38.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL38 family.
Protein: QOR_RAT
Sequence: MATGQKLMRAIRVFEFGGPEVLKLQSDVVVPAPQSHQVLIKVHACGVNPVETYIRSGTYSRKPALPYTPGSDVAGIIESVGDGVSAFKKGDRVFCFSTVSGGYAEFALSADNTTYPLPETLDFRQGAALGIPYFTACRALFHSARARAGESVLVHGASGGVGLATCQIARAHGLKVLGTAGSEEGKKLVLQNGAHEVFNHKEANYIDKIKTSAGDKGVDVIIEMLANKNLSNDLKLLSCGGRVIVVGCRGSIEINPRDTMAKETSIIGVSLFSSTKEEFQQFAGILQAGIEKGWVKPVIGSEYPLEKAAQAHEDIIHSSGKMGKMILLL
What is the function of this protein?
Does not have alcohol dehydrogenase activity.  Binds NADP and acts through a one-electron transfer process.  Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro).  May act in the detoxification of xenobiotics.  Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability.  NADPH binding interferes with mRNA binding (By similarity).
What are the official names of this protein?
Quinone oxidoreductase, NADPH:quinone reductase, Zeta-crystallin.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_RHORT
Sequence: MSLRIRLARGGAKKRPFYRIVVADSRSPRDGRFIEKLGTFDPMLPRDHERRVVLKDERVKYWLGVGALPSDRVARFLGLSGLTEARKVPEQTKQAQPKAKAQERLREAEEKARAAAEAAASAEG
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: HSLV_BACCN
Sequence: MGNFHATTIFAIHHNGKCAMAGDGQVTFGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLFEMFEGKLEEYNGNLQRAAVEMAKQWRGDKMLRQLEAMLIVMDETTLLLVSGTGEVIEPDDGILAIGSGGHYALAAGRALKRHASEHLTAKEIAKASLEIAGDICVYTNHNIIVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGD_MYCTO
Sequence: MANISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYSPEPTSQPAAEPTRVTSPLVAERAAAAAPQAPPKPADTAAAGNGVVAALAAKTAVPPPAEGDEVAVLRGAAAAVVKNMSASLEVPTATSVRAVPAKLLIDNRIVINNQLKRTRGGKISFTHLLGYALVQAVKKFPNMNRHYTEVDGKPTAVTPAHTNLGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTTEDFAGVTISLTNPGTIGTVHSVPRLMPGQGAIIGVGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHELLLSDGFWDEVFRELSIPYLPVRWSTDNPDSIVDKNARVMNLIAAYRNRGHLMADTDPLRLDKARFRSHPDLEVLTHGLTLWDLDRVFKVDGFAGAQYKKLRDVLGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVETKHVKPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVARLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYVYDVVDTKRGARKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVQPSESVESDQMIPAGLATAVDKSLLARIGDAFLALPNGFTAHPRVQPVLEKRREMAYEGKIDWAFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRHSVLIDRHTGEEFTPLQLLATNSDGSPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHKAAVSEIKDFTEIKFRSVLEEPTYEDGIGDRNKVSRILLTSGKLYYELAARKAKDNRNDLAIVRLEQLAPLPRRRLRETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSSKVHAVEQQEILDEAFG
What is the function of this protein?
Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation.  Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA).  Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha-ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy-3-oxoadipate (HOA), which spontaneously decarboxylates to form 5-hydroxylevulinate (HLA).  And is also a component of the 2-oxoglutarate dehydrogenase (ODH) complex, that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2).  The KG decarboxylase and KG dehydrogenase reactions provide two alternative, tightly regulated, pathways connecting the oxidative and reductive branches of the TCA cycle, which can endow M. tuberculosis with the metabolic plasticity required for growth on diverse host-derived carbon sources.  Appears to play a predominant role in growth on carbohydrates as the sole carbon source, and only a minimal role during growth on fatty acids (By similarity).
What are the official names of this protein?
Multifunctional 2-oxoglutarate metabolism enzyme, 2-hydroxy-3-oxoadipate synthase, HOA synthase, HOAS, 2-oxoglutarate carboxy-lyase, 2-oxoglutarate decarboxylase, Alpha-ketoglutarate decarboxylase, KG decarboxylase, KGD, Alpha-ketoglutarate-glyoxylate carboligase.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family. Kgd subfamily.
Protein: GABAT_USTMA
Sequence: MISSKATSAARACARTSRVMQQQQRRLLATVVSSSSLFPGEPSSPHVVTSQIPGPKSKELSDRIGTFQENRTHGFVVDYAKSQGNWIADADGNVLLDMFAQIASIAIGYNNPDLLALAKTDEFITATMNRAALGSFPPTNWQELVETSFGTVKPDGLNNIFTAMCGSCANENAFKASFMAYRARERGEKAEFTPEEMSSCMKNQSPGSPDLSILSFTSAFHGRLFGSLSATRSKAIHKLDIPSFNWPVVEWPDVKYPFAQNSRENAEAEKVALAAVEEAIVSSKKTGSSYGPVAALIVEPIQSEGGDNHASPAFFQGLRDVTKKHGVFMIVDEVQTGVGATGAFWAHSKWNLTSPPDFVTFSKKMQAAGFYHNIETRPSLPYRNYNTWMGDPARTLQARQIIRTIQDHNLIQKTDKVGNYIYEKLFDLIENGAGRGKIEKLRGENAGTFLAFDGRTAKVRDQLIMEMRKLGVHMGGCGDKALRLRPMLVFEQKHADIFLDKLETALGQL
What is the function of this protein?
Deaminates gamma-aminobutyric acid (GABA) to succinate-semialdehyde, which in turn is converted to succinate by the succinate semialdehyde dehydrogenase (By similarity).  Not required for the utilization of GABA as nitrogen source.
What are the official names of this protein?
4-aminobutyrate aminotransferase, GABA aminotransferase, GABA-AT, Gamma-amino-N-butyrate transaminase, GABA transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.