PharMolix/UniProtQA huggingface dataset:
Protein: RL6_XYLFA
Sequence: MSRVAKKPISVPKGVEVSVRSDMLTVKGVKGVLTFPKSDNVNVVVDGDILTLSANDPSHVSLAGTVRAILSNMIKGVSIGFERKLELVGVGYRASMQGENLNLSLGFSHPLVFVPPEGITLLTPSQTEVVVQGIDKQRVGEVAAKIRSFRPPEPYKGKGLKYAAEAIMRKEAKKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TDH_COXB2
Sequence: MKVLSKLKPAPGLWLHKAPTPKPGRDEVLIKIKKTAICGTDLHIYKWDEWAQKTIPVPMHVGHEFVGEIVEVGEAASALAVGDRVSGEGHITCGDCRNCRAGKRHLCRYTVGVGVNRPGAFAEYLVIPAKNAYKIPAKISDDIAAILDPFGNAAHSALEFDLVGEDVLITGAGPVGLMSAAIARHVGARHVVITDVNDYRLALAEKVGVTAAVNSTKTPLTETMKNLGMTEGFDVGLEMSGNAEAFRSMLTVMNNGGKIAFLGIPPEPFAIDWNQVVFKSLLIKGIYGRRMFETWYKMTNLLLSGLDISPIITHEFPMKDFQQAFDVMLSGKTGKVILNWEQ
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HZG_DROME
Sequence: MDATSIITQVSRDDEQLNVYPSYPNDKDAWLGFSGSVWLPDCPADHAQLTHDVDRLKPQKRGLFHSLLCCWRRNRTKTNQNGTQIDGSTTPPPLPDQQRYLLPQVRLTDMHRKCMVIDLDETLVHSSFKPIPNADFIVPVEIDGTVHQVYVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVADLLDKWNVFRARLFRESCVYYRGNYIKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKSWFDDVTDCELRELIPLFEKLSKVDSVYSVLCNSNQPLNNQTNQQQHPQELQQAPNQLHQQLQQQQQQQTISATTVITQATTLSAPTMLNQQQTSPPSPQSELLQKT
What is the function of this protein?
Prion-like membrane-associated phosphatase (PubMed:31491385).  Phosphatase activity depends on amyloid-like assembly at the membrane (PubMed:31491385).  Might have a role in establishment of segment polarity in embryos (PubMed:31491385).
What are the official names of this protein?
Phosphatase Herzog.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=During embryonic development shows diffuse localization between stages 1-5 and then shows foci formation at the cell membrane that persist till later stages.
Protein: BIOF_BACC1
Sequence: MNQTWRTHLQSKLQQLHERGQYRNLHVTEQAEETWLIRDEKRMLNLASNNYLGLAGDERLKEAAIACTRKYGTGATASRLVVGNYSLYEEVERSICDWKGTEKALVVNSGYTANIGVISSLVSRHDIVFSDKLNHASIVDGIILSGAEHKRYRHNDLDHLEKLLKTASPEQRKLIVTDTVFSMDGDTAYVRELVELKEKYGAILIVDEAHASGIYGSGGAGLSHIEEDLAQKIDIHMGTFSKALGCYGAYLTGDAIYIEYLHNMMRSFIFTTALPPGTLGAVQKAIEIVKEDNERRERLIENGAYFRNHLREAGFDIGNSSTHIVPIVVGSNETALRFSKRLQQVGIAAIAIRPPTVPVNSSRVRFAVTSQHTIADLQWAIHHIIRIGKEEGFFV
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: YIDD_SHEDO
Sequence: MAQAQSPLQWLATTVIRGYQLFISPLMGPRCRFNPTCSHYAIEAIKLHGTAKGSWFALKRILRCHPLHPGGSDPVPPKNDRCNK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RRF_ORITI
Sequence: MNHEELINSLTKKMNGALQVLDADLKGLRVGQASAYFLDPVQVEAYNSKVPILQVATISVSDTKTILVQVWDKSLVKAVKKAIMEANLGVSIISDDNQIIRLQLPIPSEERRKELVKIAHKYQEKSKIIVRNIRRDGIELIKQMEQNTECSKDEAHIYSKEIQELTDKYCDKIDKIIKLKEQDIINL
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_HELHP
Sequence: MQRVKTKQIFVGNVAVGGDAPISVQSMTFSKTCDIEATKAQLDRLYFAGADMVRVAVSDPKDADALKDLKKVSPLPLIADIHFRYKFALIAAESVDCIRINPGNIGSKDRIKAVADACNARGIPIRIGVNGGSLEKQFEEKYGATPKGMVESALYNIKLLEDFGFSNIKISLKASDVLRTMEAYRMLRPLVDYPFHLGVTEAGTLPHSMIKSAMALGGLLMEGIGDTMRISITGELEEEIKVARLILQYSGRQKSGVSIVSCPTCGRIEANLVKMVQEVESRIKHIKIPLQVSVMGCAVNALGEAKHADIAIAFGNKDGLIIKEGKILCKLKEDQLLERFITEVEELAKQREEV
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: HIS7_DICTD
Sequence: MRKSEIERETKETYVKILLNLDGSGSFLGDFPVPYYKHLFSAFCFYAEWDVEIMAKGDVEVDPHHLIEDTGIVWGKAFYSAVSNSNFLRFSSKIVPMDEALVMAVVDISGRPYLEIRDDKGILNGRLIKEFLRGFVNNSQITLHIWLLSGENLHHIEEAIFKALGLALGEASKEVPNLKSTKGKIW
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQB_PSEPG
Sequence: MYIQVLGSAAGGGFPQWNCNCVNCKGYRDGTLRATARTQSSIALSDDGVHWVLCNASPDIRAQLQAFAPMQPARALRDTGINAIVLLDSQIDHTTGLLSLREGCPHQVWCTDMVHQDLTTGFPLFNMLSHWNGGLQWNRIELEGSFVIEACPNLKFTPFPLRSAAPPYSPHRFDPHPGDNLGLLVEDTRTGGKLFYAPGLGQVDGKLLAMMHDADCLLVDGTLWEDDEMQRRGVGTRTGREMGHLAQNGPGGMLEVLDGFSRQRKVLIHINNTNPILDEDSPERAEVLRRGVEVAFDGMSIEL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: APAG_SALEP
Sequence: MINSPRVCIQVQSVYIEAQSSPDDERYVFAYTVTIRNLGRAPVQLLGRYWLITNGHGRETEVQGEGVVGVQPRIAPGEEYQYTSGAVIETPLGTMQGHYEMIDENGDAFTIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: PABP4_HUMAN
Sequence: MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS
What is the function of this protein?
Binds the poly(A) tail of mRNA.  May be involved in cytoplasmic regulatory processes of mRNA metabolism.  Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein 4, PABP-4, Poly(A)-binding protein 4, Activated-platelet protein 1, APP-1, Inducible poly(A)-binding protein, iPABP.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: Y1344_THEON
Sequence: MIIIVTGMPGSGKSKIVKEFEKRGVPSVSMGDVVREETAKRGLELTKENVAKVSIRLRQELGQNAVAKLAVEKVRELLRKNKVVVIDGVRSLDEVGTFRSAFPGEEIIIVAVHTPPHMRFERLKARGRHDDPQSWEDFEERDWKELKFGIGNVIAMADYMIVNDCPKEEYERRVQELVEKILAEH
What are the official names of this protein?
UPF0200 protein TON_1344.
What is the protein family that this protein belongs to?
Belongs to the UPF0200 family.
Protein: VA0E2_RAT
Sequence: MTAHSFALPVIIFTTFWGLIGIAGPWFVPKGPNRGVIITMLVATAVCCYLFWLIAILAQLNPLFGPQLKNETIWYVRFLWE
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:32165585).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:32165585).
What are the official names of this protein?
V-type proton ATPase subunit e 2, V-ATPase subunit e 2, Vacuolar proton pump subunit e 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase e1/e2 subunit family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Protein: CYSE_STAES
Sequence: MLKRMRDDIKMVFEQDPAARSTLEVITTYAGLHAVWSHLIAHKLYKNRRYVAARMISQLSRFFTGIEIHPGAKIGKRLFIDHGMGVVIGETCTIGDNVTIYQGVTLGGTGKEKGKRHPDIGDNVLIAAGSKILGNIKIESNVNIGANSVVLQSVPSYTTVVGIPGHIVKQEGRRIGKTFDHRNLPDPLYEQIKHLERQLEKAKNGEIQDDYII
What are the official names of this protein?
Serine acetyltransferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETT1_CLAL4
Sequence: MAPKRPLGIGKAAKAKKQKKESTENESVGETAASNELTVELDEEIEANDAVAQLKALWKTYFASEDKSELMLNGIIHECDRILRKTHNTKEQDEDDEKIELSGRFYAIYALALSSLAFYHTEDLKKVNDFFAEAFDRIESGRKAFPDSVDLAFAEAKIMISRIPLVEVSQLLVDSRVGKERSDVSKSLDASLAKWEEAQKQAVAQNHFHHYNAENFDFLQALDDLLDMVDNFGQEIMEGEDSDAEEDEKPHVELDEGHPLFAIKSSDKYNLWWREQTIAFLDHLNKNIENASAKELPALAVLKRELCKRLGQSYLMEAEVPANVFTTLSYYSKDAKSLNGLTRVEAQKISQDLFKRALTYLKQAQDEQEPETWVNVAEAMISLGNTYEIDSKEQEETYKEAEAILVKANNATNGKYEDILENLMQG
What is the function of this protein?
Required for correct translation termination and probably involved in regulation of hypoxic gene expression.
What are the official names of this protein?
Enhancer of translation termination 1.
What is the protein family that this protein belongs to?
Belongs to the ETT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EXGA_EMENI
Sequence: MFPRISQAAILAHSLLAVCTSAATLAEKVRGVNLGGWLVLEPWITPSLFDEAGDEAVDEYTLTEVLGVEEAAARLSEHWNTFITEEDFALIAEAGLNYVRIPIGYWAAAPLDGEPYVSGQLEHLDNAVAWARAHNLKVIVDLHGAPGSQNGFDNSGRRGPIGWQQGDTVEQTILAFETLAQRYLADDDTVTMIEALNEPHVPGGINQDQLKDYYEETLARVRKNSPEATLLLHDGFVQTEGWNGFMTGENVMMDTHHYEVFEGGQNAWSIEKHIDAACQLGRQHLQAADKPVIVGEWTGALSDCTRYLNGKGIGIRYDGTLGSNTAVGACGSKSEGSVAGLSADEIANTRRFIEAQLDAFELRNGWVFWTWKTEGAPGWDMQDLLANGVFPQPLTDREFPNQCNF
What is the function of this protein?
Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall.  It could also function biosynthetically as a transglycosylase (By similarity).
What are the official names of this protein?
Probable glucan 1,3-beta-glucosidase A, Exo-1,3-beta-glucanase 1, Exo-1,3-beta-glucanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCST_GEOTN
Sequence: MLKRTPLFPVYARYGAKTVEFGGWEMPVQFSSIKEEHNAVRTRAGLFDVSHMGEIIVRGGGSLPFLQKLMTNDVAKLRPGRVQYTLMCDESAGTVDDLLIYQKGEDDYLLVVNAANTEKDFAWLSEHADGDVELEDVSAETALLALQGPAAERVLQKLTDMDLSALRPFSFQDGVEVASVKTLVSRTGYTGEDGFELYCQAEDAITLWEAILTAGAEDGVLPCGLGARDTLRFEACLPLYGQELSATISPLEAGLGFAVKTEKEPPFIGQAVLKQQKEAGPPRRLVGIEMIDKGIPRHGYRVFAAGEEAGFVTTGTQSPTLKKNIGLALVKAEVAAIGQEVEVDIRGKRLKATIVPTPFYKRAKS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: CSRA_DESRM
Sequence: MLILSRKKNESIHIGDNIIITVVDIGGDNIKIGIDAPKNVQIFRSELLKAVEQENKNAVSSKSVIQDLAQLIKGDEKKQT
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_SYMTH
Sequence: MKLPLVVLVGPTAVGKTALSVAVAQAVGAEIISGDSMQVYRGMDIGTAKIRPEEMGGVPHHLIDIKDPDEEFSVAEFQARVDALIPQICARGRLPMLVGGTGLYVRAVVEKYTFTPMEADHELRARLRQEEERHGPGYLHARLREVDPASAARLHPNDLLRIVRALEVYEQTGVPISATQTAAFSEPRYDDLMIGLTMDRAQLYARIDERVDAMLAAGWLDEVRGLLVRYPPHVRAMQALGYRELVLYLRGLLTWEEAVALIKRNTRRFAKRQFTWFRKERRLTWLDLTGPEARNRATEEIVRLIREKWPCRERKGRIE
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GOT1_SCHPO
Sequence: MWLSDLQKIGVGTTALGFLFMIMGIFMFFDGPLLSLGNLLLVFGFFMIAGFSKSVSFFLRKDRMLGSISFFSGLLLTLFHFPIIGFFVECLGFFNLFKVFYPLIISFLRTVPYIGPYIDRLTSYQQSPV
What is the function of this protein?
Nonessential protein required for the fusion of ER-derived transport vesicles with the Golgi complex.  Can be replaced by sft2 (By similarity).
What are the official names of this protein?
Protein transport protein got1, Golgi transport protein 1.
What is the protein family that this protein belongs to?
Belongs to the GOT1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: HIS8_CAMHC
Sequence: MKFNDYVENLQNYEAGKPVELVVREYGVKEDDVIKLASNENPLGTGKKAVKAIYKMAKHANLYPDDSMFELKGALADKYGVSEKNVIIGAGSDQIIEFLIHAKCNENNGILTAGTTFSMYGIYAKHAKAKHFSTASKFHDLKEIKELYESHKDEISVIFLCVPNNPLGECLDAKDVIKFIKSIDDDTLVVIDAAYNEFASFKDKHKHIEPAEIVKLKNAIYLGTFSKVYGLGGLRVGYGVADEKIISALYKLRPPFNVANLSLAAAVAALQDKKFIEKTIKNNFKEMKKYEKFANATGIKFIKSYTNFITFILDESKKSSEISQKLLEKGLIVRDLKGYGLNAIRITVGLPKQNKRIFDELRKLLG
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SFGH2_ECOHS
Sequence: MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPPVLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEKVANDDGYDLGQGAGFYLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPGKYTSVSAFAPIVNPCSVPWGIKAFSSYLGEDKNAWLEWDSCALMYASNAQDAIPTLIDQGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYLLK
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase YeiG, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: DG2L6_BOVIN
Sequence: MAFLSQLNLQEILQTLSVLQWMPVYVFLGAIPIIVIPYFLVFTKFWMVSVLALAWLAYDWNTHSQGGRRSAWVRNWTIWKYFQNYFPIKLVKTHDLSPRHNYIIASHPHGVLPYGTFINFATETTGFARIFPGITPYVATLEGIFWIPIVREYVMSMGVCPVSELALKYLLTQKGSGNAVVIMVGGGAEALLCHPGATTVLLKQRKGFVKVALETGAYLVPSYSFGQNEVHNQETFPEGTWKRFFQKALQDTLKKLLRLSVCTFHGRGLTRGSWGFLPFNHPITTVVGEPLPIPRIKKPNEETVDKYHALYINALQKLFDEHKVQYGLSETQELTII
What is the function of this protein?
Diglyceride acyltransferase that uses fatty acyl-CoA as substrate.  Particularly active with oleate as a substrate.  Has no wax synthase activity to produce wax esters.
What are the official names of this protein?
Diacylglycerol O-acyltransferase 2-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AROQ_SYNS9
Sequence: MHVLLLNGPNLNLLGQREPGIYGCDTLATIETELTREAKADGVELVCFQSNFEGALIERIHQAMGESQGILINAGAYTHSSIAIRDALTGVAIPYVELHLSNTHAREPFRHQSYLAGRAVGVVSGFGAKSYSLALSGLVHHLRQGG
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: HEM2_ASHGO
Sequence: MKHTAEFLDTHQTQISSILSGGYNHPLLREWQNERQLAKNMFIFPLFVSDMPDEDQPIESLPNIRRFGVNKLAGYLKPLVAKGLRAVLLFGVPMKPNSKDEFGSAADDPEGPVIQAIKLLRAEFPELYILCDVCLCEYTSHGHCGVLYDDGSINREQSVRRLAAVAVNYAKAGAHSVAPSDMIDGRIRDIKLGLLAAGLAHKTFVMSYAAKFSGNLYGPFRDAACSAPSQGDRKCYQLPSGGRGLARRALRRDLDEGADGIIVKPSTFYLDIMADASEIAKDVPICAYHVSGEYAMLHAAAKAGVVDFKSIAFESHQGFLRAGARLIISYMTPEFLDWLS
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: STBA_PSEUB
Sequence: MTTLNVARVYLRVSSEDQDLQRQEAIIGNARESGYYVAAVYREKASGARSDRPELLRMIEDLQPGEVVIAEKIDRISRLPLVEAEKLVDAIRAKGARLAVPGIVDLSQLTEASRGVAKVVLQGVQDMLLRVALQIARDDFEDRRERQRQGIDLAKGAGRYAGRKPDTKMHERVIALKSGGCSIAETARLAGVSVSQVKRVWAQNQTKDKV
What is the function of this protein?
Site-specific recombination protein.
What are the official names of this protein?
Resolvase.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: FOLD_ERWT9
Sequence: MVAKIIDGKTIAQQVRNEVAGLVQQRLAAGKRAPGLAVVLVGENPASQIYVSSKRRACEEVGFLSRSYDLPASTSEAQLLELITQLNDDAEIDGILVQLPLPAGIDNTKVLEHISPAKDVDGFHPYNVGRLCQRAPTLRPCTPRGIVTLLERYQIDTFGLNAVVVGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRQHIENADLLVVAVGKPGFIPGDWIKPGAIVIDVGINRLESGKVVGDVDFDLASTRASWITPVPGGVGPMTVATLIQNTLQACENNDNGVSA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: VP5_AQRVC
Sequence: MITIVVIPTAHFSWTDTNFLNSVDYRLTSQPKIRDRFAVYAPGWLRRQLDEFSASLTASELLQALQTIPIPVKARCLLLPKPKRFAQWLLDVPSANIWHIPVTTLRATVASKHPSSDVYNYIPDHVPPSAEFDTVTRRVAAGRDIYVRSTKVLGAPLCLAAPAKYYAGYLSTHQLDGVYPDNWAPDNFHKREFCLTILPSLLGPRTFLLDVDADRDASYPLSVLWPQLRVLALKSRLLLPPVALLRRVVDPGLKPTWSADSDAAFRALRLSRPSSASKPTGFDFSALPVVDIICLFESEPDDHGRVAPGTRLTIHSVPTDLLTSLSIQEGVRYPLRQESGMFVPWVLLALLMSDDVTISGTRRSVKLETAHASARPFVHITVERCASARVVDVRGSPAMYANAVCLTLPKGSYKSTIIDTLPAMFSDLSILEQAAVIDSDALGDSLRPSFETQFLERLENLDPKLLDRAVASILSPASDTSDDAVTTVLDVFNALYREVMTPAQRSRLPLLTQQGRVLAFAHSDYELLSANIPIQVVRGSIPIDHVVNLLARRNRVGGTALQVLLDYCYRTQASPLAPTPAGRLYKQLFGPWLMVPRLSDPLIKLRLVASAPAKVLRAAGWTIDGDPPLEVSCLCAYVTDRAMAAALIERRLDSRALVNVGGDQLMFVEYAPPLPLVSIPRTFLLPVTYVVHWVSPQRVLLNGGNVSFTSGLEWTFDDDPQVVTSTGV
What is the function of this protein?
Minor inner capsid component.  Displays NTPase and RNA 5'-triphosphatase (RTPase) activities.  May function as a cofactor of polymerase.  Associates with microtubules and plays a role in the formation, structural organization and morphology of viral inclusions, where the assembly of cores and the replication of viral RNA occur (By similarity).
What are the official names of this protein?
Microtubule-associated protein VP5.
What is the protein family that this protein belongs to?
Belongs to the reoviridae microtubule-associated protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host cytoskeleton.
Protein: GDAP2_XENTR
Sequence: MDPLGARSCFVDADALPCWADVRDGEGEDVPDGGRKDAPHGGLHSPFPYRNDINKKVILWRGDVALLSCTALVNTSNETLTDKNPVSDSIFRYSGPELSEEMQKLKGCRTGEAKLTKGFNLAARYIIHTVGPKYKTKYRTAAESSLYSCYRNVLQLAKEQGMASVGFCVIATQKRCYPPEDSTHIALRTVRRFLEAHGAALEKVVFAVTEQEEGTYRRLLPLYFPRSLEEEQRSIPFLPQDIGNAEGEPVVPERQIRISEKPGGQDDDSEEEGLVKDLSVIGSHAFARMEGDVDKQRRLALQGQLSGAAMQKQHQRNYNRWLSRARTEDLSDIAALKALYQSGVDNCGRTVMVVVGRNIPVLLIDMEKALLYFIHMMDHVAAKEYVLVYFHTLTGEHNHPDSDFLKNMYDIVDVKYKKNLKALYFVHPTFRSKVSSWFFTTFTVSGLKDKVHQVESLHQLFSAVPPEQIEIPPFVLDYDARENGPFFPSQSSFLSL
What are the official names of this protein?
Ganglioside-induced differentiation-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the GDAP2 family.
Protein: MLRV_HUMAN
Sequence: MAPKKAKKRAGGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD
What is the function of this protein?
Contractile protein that plays a role in heart development and function (PubMed:23365102, PubMed:32453731).  Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force.  These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity).  During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity).
What are the official names of this protein?
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, MLC-2, MLC-2v, Cardiac myosin light chain 2, Myosin light chain 2, slow skeletal/ventricular muscle isoform, MLC-2s/v, Ventricular myosin light chain 2.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, A band.
Protein: SUS_BETVU
Sequence: AGGKQILSDGPFSEVLRSAQEAIVVPPFVAIAVRPRPGVWEYVRVNVSELNVEQLTVSEYLHFKEELVDGKADDHYVLELDFEPFNESVPRPTRSSSIGNGVQFLNRHLSSSMFCNKDCLEPLLDFLRVHKHKGVVMMLNDRIQTIQRLQSALSKAEDYLIKLPADTPYSEFEFVIQGMGFERGWGDTAERVLEMMHLLLDILQAPDPSTLETFLGRLPMVFNVVILSVHGYFGQAHVLGLPDTGGQIVYILDQVRSLEHEMLQRIKKQGLDVTPRILIVSRLIPDAKGTTCNQRMEKVSGTEHASILRVPFRSEKGILRKWISRFDVWPYLETFTEDAAGEIIGELQGRPDLIIGNYSDGNIVASLLSHKMGVTQCNIAHALEKTKYPDSDIYWKRFEDKYHFSCQFSADLMAMNHADFIITSTYQEIAGTKNTVGQYESHKAFTFPGLYRVVHGIDVFDPKFNIVSPGADMAIYFPFSEKDVTCLTSLHRLIEQLLFKPEQNEEHIGVLDDTSKPIIFSMARLDRVKNITGLVECYGKNAKLRELANLVVVAGYNDVKKSNDREEIAEIEKMHRLIQEYNLRGQFRWIASQTNRVRNGELYRYICDKGGIFAQPAFYEAFGLTVVEAMTCGLPTFATCHGGPAEIIEDGVSGFHIDPYHADQAEKMTEFFVKCREDPNYWTKISAGGLLRIKERYTWQKYSERLMTLAGVYGFWKYVSKLERRETRRYLEMFYILKFRDLANSVPLATDEEPSTTDAVATFRGP
What is the function of this protein?
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.
What are the official names of this protein?
Sucrose synthase, Sucrose-UDP glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily.