PharMolix/UniProtQA huggingface dataset:
Protein: HPPK_ECOLI
Sequence: MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTPPLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLFGNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGEMLRQILHTRAFDKLNKW
What is the function of this protein?
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
What are the official names of this protein?
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
What is the protein family that this protein belongs to?
Belongs to the HPPK family.
Protein: MNME_ACAM1
Sequence: MKQTTIAAIATAIVPQQGSIGIVRLSGVEAVSIAKQLFQTPGKQQWESHRVLYGYIQQPLTQQIIDEGLLLLMLAPRSYTREDVVEFHCHGGMIAVQQVLEACLQAGAELAQPGEFTLRAFLNGRLDLTQAEGVADLVGARSPQAAQAALAGVQGKLASPIRELRQRCLDTLAEVEARVDFEDDLPPLDEAGVQAELQDIHATLQAILATADQGELLRNGLTVAIIGRPNVGKSSLLNAWCRCDRAIVTDLPGTTRDVVESQLVVGGIPIQVLDTAGIRETEDQVEQIGVTRSHQAAQSADLVLLTIDASVGWTSDDQQLYQAFQDLPLILIVNKVDLVPQEQVVYPEAIAQVVSTIAAQNQGISELETAILETVQTQSLKAANLDWAINQRQAAALQKAQAALEHVQGAIADQLPLDFWTIDLRGAIQALGEITGEDITESVLDRIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG32_YEAS8
Sequence: MVLEYQQREGKGSSSKSMPPDSSSTTIHTCSEAQTGEDKGLLDPHLSVLELLSKTGHSPSPMGQNLVTSIDISGNHNVNDSISGSWQAIQPLDLGASFIPERCSSQTTNGSILSSSDTSEEEQELLQAPAADIINIIKQGQEGANVVSPSHPFKQLQKIISLPLPGKEKTPFNEQDDDGDEDEAFEEDSVTITKSLTSSTNSFVMPKLSLTQKNPVFRLLILGRTGSSFYQSIPKEYQSLFELPKYHDSATFPQYTGIVIIFQELREMVSLLNRIVQYSQGKPVIPICQPGQVIQVKNVLKSFLRNKLVKLLFPPVVVTNKRDLKKMFQRLQDLSLEYGEDVNEEDNDDEAIHTKSRSYCRNKKAENSKKKSPKSNKKPKRKKQKFFTSWFTWGISITIGISFGCCVTYFVTAAYEHQTVKSLSLRPSILASLLSLDSSSDTINTPATASPSSTEQFLWFDKGTLQINFHSDGFIMKSLTIIKETWGKMNTFVLHALSKPLKFLENLNKSSEFSIDESNRILALGYILL
What is the function of this protein?
Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria.  Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Recruits ATG11 to the surface of mitochondria.  Promotes also autophagy-dependent peroxisome degradation (By similarity).
What are the official names of this protein?
Autophagy-related protein 32, Extracellular mutant protein 37.
What is the protein family that this protein belongs to?
Belongs to the ATG32 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Vacuole membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass membrane protein. Note=Is recruited to the preautophagosomal structure during mitophagy and imported into the vacuole along with mitochondria during starvation.
Protein: RS14_LATSS
Sequence: MAKKSKIAKLAKQRALVAKYADLRATLKAEGNYAALAELPKDSSPVRLRNRDLIDGRPRSFMRKFGMSRINFRELAHKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: TRUA_BRASB
Sequence: MPRYKLTIEYDGTPFCGWQLQETLPSVQGALEAAVQATCGVPTRVHGSGRTDAGVHATGQVAHCDIAKDFRPDKLRDALNAHLRPNPVAVLEAEIVSDTFEARFSARKRHYRYRIVNRRSNLALEVGRVWRVPQRLDSDAMHAAAQRLIGRHDFTTFRDTECQAKSPEKTLDQLDVVRDGDAVTILTSARSYLHSQVRSMVGSLVWVGQGRWSADDLAAALAARNRAACGVVAPPEGLYLVKVDY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: Y712_SHEPC
Sequence: MKLVIVSGRSGSGKSVALRVLEDLGYYCVDNLPLPLIGSLLEQLKGSNDLVAISVDVRNMPEQDKVLVQQLSNLPAGTEITSFFLNSSDKVLLKRYSETRRLHPLSKSRVSLQEAIKLEGKLLEPMSKLVDHYIDTSNLNIYDLSDQVRQILLGSVDKELVIYFESFGFKNGMPTEADFMFDVRFLPNPHWELALRPLTGLDEPVAEFLNRQPLVNKFIWQIENLLETWLPHLERNNRSYLTIAIGCTGGQHRSVYVAEQLAKRFSNGKHKVNVRHRELDNAKA
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Sputcn32_0712.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RIMS1_MOUSE
Sequence: MSSAVGPRGPRPPTVPPPMQELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMAKPAACKTPRNAESQPHQPPLNIFRCVCVPRKPSSEEGGPDRNWRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICHKTKFADGCGHLCSYCRTKFCARCGGRVSLRSNNEDKVVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEVPREKKARLQERSRSQTPLSTAAVSSQDTASHGAPLDRNKGAEPSQQALGPEQKQASRSRSEPPRERKKAPGLSEQNGKGGQKSERKRVPKSVVQPGEGTADERERKERRETRRLEKGRSQDYPDRLEKREDGRVAEDEKQRKEEEGVSTPEYTSCEDVELESESVSEKGDLDYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKLLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQDEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGESSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRASARESKATTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSLADHRSRHAESQYSSEPDSELLMLPRAKRGRSAECLHMTSELQPSLDRARSASTNCLRPDTSLHSPERERGRWSPSLARRRPASPRIQIQHASPENDRHSRKSERSSIQKQSRKGTASDADRVLPPCLSRRGYAIPRATDQPVIRGKHTTRSRSSEHSSIRTLCSMHHLAPGGSAPPSPLLTRTHRQGSPTQSPPADTSFGSRRGRQLPQVPVRSGSIEQASLVVEERTRQMKMKVHRFKQTTGSGSSQELDHEQYSKYNIHKDQYRSCDNASAKSSDSDVSDVSAISRASSTSRLSSTSFMSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEIYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRVGPDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSSGPPCIRS
What is the function of this protein?
Rab effector involved in exocytosis (PubMed:11797009).  May act as scaffold protein that regulates neurotransmitter release at the active zone.  Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity (PubMed:11797009).  Plays a role in dendrite formation by melanocytes (By similarity).
What are the official names of this protein?
Regulating synaptic membrane exocytosis protein 1, Rab-3-interacting molecule 1, RIM 1, Rab-3-interacting protein 1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Synapse. Presynaptic cell membrane; Peripheral membrane protein.
Protein: RAB3_DROME
Sequence: MASGGDPKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNANCNC
What is the function of this protein?
Involved in exocytosis by regulating a late step in synaptic vesicle fusion.  Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity).
What are the official names of this protein?
Ras-related protein Rab-3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
Protein: APL2_PETMA
Sequence: MLSTKMTHAAGLLLLVLTAYVQADETQLVPATGKTYLETALERLHSYGEAVSGDKADGIMTEARELVEQFMEEFQAKALPEGVTTHKLAEEMAEAANAKLVPILQAAKAGIERVTAHLHESAPLIIKVRGFIESKRGVMWAYLAALAERAKKAKLDDTLKGVRDGLTALTLSSIGLMKEVKEIASAPPPAQ
What are the official names of this protein?
Blood plasma apolipoprotein LAL2.
What are the subcellular locations of this protein?
Secreted.
Protein: TI172_ARATH
Sequence: MGTPETSREPCPDRILDDIGGAFGMGAVGGSAFHFIKGTYNSPKGSRFVGGTQSVSMNAPRTGGSFAVWGGLFSTFDCTMVYLRQKEDPWNSIIAGAATGGFLSMRQGAGAASRSAIFGGVLLALIEGAGIMLNKVLAQPQNMMMEDPGMQGMPGMQGMQGMPGMPGMQGMPGMQGMQMGQMQSQAQIRSESQNQNTASSSSSSSWFGGLFDKKKEEVQPGSESKTEVLESFDAPPVPSFEFK
What is the function of this protein?
Essential component of the TIM17:23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Links the inner and outer membranes.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM17-2.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Mitochondrion outer membrane. Note=The C- terminal region is located in the outer membrane.
Protein: ACDH_PSESP
Sequence: MSDDRLSVAIIGSGNIGTDLMIKIMRNSKLLKVGAMVGIDPKSDGLARAQRLGVPTTAEGVDGLLDMPAFRDIKIAFDATSAGAQAIHNQKLQAHGVRVIDLTPAAIGPYVIPVVNFDQHVDAPNINMVTCGGQATIPIVHAVSKVSPVHYAEIVASISSKSAGPGTRANIDEFTETTSKAILEVGGAAQGRAIIILNPAEPPLIMRDTVYCFVSAEANIDAITDSVEQMVKSVQEYVPGYRLKQKVQFEKIVAGNEQNIPGLGWSTGLKVSVFLEVEGAGHYLPSYAGNLDIMTSAGLTVAERIAGSGVQVGGLK
What is the function of this protein?
Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A.  Is the final enzyme in the meta-cleavage pathway for the degradation of 2-aminophenol.
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RL18_HERA2
Sequence: MSKFTSRELRARRHRRLRGQLSGTPERPRLNVFRSGLNIYAQVIDDLAGHTLVSASTIDTELRGSLGEQRKLEQAHSVGKAVAERARAAGITKVVFDRGGYKYHGRVKAVAEGAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RGYR2_AQUAE
Sequence: MALELIERGCPNCGGVISSDRLEKGLPCSKCLPKPTEEKVCDALEELKTLKYLKPFCDTDKSLERFINFFEKAVGAKPWSLQRVWAKRVFMNQSFAIVAPTGVGKTTFGLVMSLFLKGRVLAIFPTRLLAQQAGDRLSELAQKVGVNKKILIYQSKKNIREQFLNGDWDILLGTNMFLHKNFENLINFKFKLIFIDDIDSFLKRGKNVDYLFKLLGFSGEEIKLALKENKTQRDYDRLARIRKRKRDTVLIVSSATLKPRGKRAYLFRNLLGFDVQKAITTLRNIVDVAEPVKDLEEALEKSVELIKKLGKGGLVYLSVFYGKDKVQEVKEFYRKHGINAVSYLDYKPEELYQILEKGEFDVAVGISHITNPLVRGIDLPHIIRYAVFLDPPKHVFPTELTLSPPLLHGLLLTLLNLFEGDDRLKAIQYVMYLKRYLTLREEQLDNYPRIKERVEEIKNFLENYLKDENFLKKIKESEDISLVPKEGKLYIVVGDANSYIQASGRTSRFIAGGMTKGLSVVYYSDPKAFYSLKKRLALYYMTQEIEFKRLSEVDLNKLIKEIDEDRKRAREILQGKGVAQIKDLFKTTLVIVESPNKARTIAGFFGKPQMRLVEDSVAYEVPLGDRLLVITASLGHVLDLVTDKGFFGVLDDTYPYLPVYDTIKICRETHEQHTEYEYLKKRCKGKIEDKLEIIKGVREVSYEVDEVFIATDPDAEGEKIGYDLYLLSKPFNFNIKRAEFHEVTPKAFREAIQNPREVDLNLVKAQLVRRILDRWVGFTLSHILWDAFGKKWLSAGRVQTPVLGWVIKRYEESKEKKGEILLHVNDFPLKIEIEDLMFAKEIFKDLELADISLSNPQEEEKRPLPPYTTDTVLEDANEKLHLSAHKTMKILQELFEAGYITYHRTDSTRVSDAGKYLVAKPYITKMFGEEYFYPRSWGEGGAHECIRPTRPLEPKDLEFMITAGIAEFEDPENALKVYELIFKRFMASQMRPAKVITEEIILKLPYFEWKERVVTEVKEHGFDLMYPTFKVFPKKEKLEITHKEFREVPKVYPYTQGTLIQEMKRRGLGRPSTYAQIVQTLLERHYVVEEKGFLIPTDLGREVYEYLTKHFPEWTSEELTRKLEEAMDKIERGELDYMEVLKEVHRIKVLLKEEKAFKK
What is the function of this protein?
Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process.  It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue.  May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
What are the official names of this protein?
Reverse gyrase 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
Protein: PLSX_SYNE7
Sequence: MTRARIAVDAMGGDFAPEEIVKGALRAQEELQADVILVGDPDRLRAICQDHAPHLQVRIEAAEEAIAMEDAAVSVRSRPRASINVAMDLVKAGEADAVISAGHSGAVMASALLRLGRIRGIDRPAIGALLPTVIPGKPVLVLDVGANVDCKPRFLEQFAVMGSIYSRDVLGQANPRVGLVNIGEEDSKGNELALASHQLLRNNPRICFVGNAEGRDVLSGQFDVVVCDGFVGNVLLKFAEAVGSVFLEIIRDELPRGMRGKVGSTLLRRNLRRIKQRLDHAEHGGALLLGVNGICIISHGSSKAPSIYSAIRLAVEAAENRVIDHLHQIQEPPSPAADLVTEPVVS
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: BUTA_STAAM
Sequence: MTNNKVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSNRDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAHEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFAPGIVQTPMMESIAVATAEEAGKPEAWGWEQFTSQIALGRVSQPEDVSNVVSFLAGKDSDYITGQTIIVDGGMRFR
What is the function of this protein?
Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.
What are the official names of this protein?
Diacetyl reductase [(S)-acetoin forming], Acetoin(diacetyl) reductase, AR, Meso-2,3-butanediol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RL30_BRUME
Sequence: MAEKKGKTVTVEQIGSPIRRPAEQRATLIGLGLNKMHRRSTLEDTPAVRGMIAKLPHLVRVVDEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TTC17_RAT
Sequence: MAAAIGVRGRFELLSCSGPGWLISLSALLSVVARGALATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDVRPEDFIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNSSSWVLYNLASFYWRIKNEPYQVVECTMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSAFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGDDSSTSSMMSVNFDVPTNQSDVSESVRSSPVAHSVLWVWGRDSDAYRDKQHILWPKRADCTDSYPRVPLGGELPTYFLPPENKGLRIHELTSDDYSSEEEAQTPDCSITDFRKSHTLSYLVKELEVRMDLKAKIPDDHARKILLSRIKNYTIPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQALAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLTTRCPECESSLKLIRCMQFYPFLYNITSSVCSGHCHEKTLDNSHDKQKYFAKPQSLDAAEEEPSRHGADEDPVLSVENAGRDSDALRLESTVVEESNGSDEVEKSEETKMSEEILALVDEFQQAWPLEGLGGTLEMKGRRLDLQGIRVLKKGPQDGVAKSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQEKKRDYQSMGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVVVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP
What is the function of this protein?
Plays a role in primary ciliogenesis by modulating actin polymerization.
What are the official names of this protein?
Tetratricopeptide repeat protein 17, TPR repeat protein 17.
What is the protein family that this protein belongs to?
Belongs to the TTC17 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton. Note=Localized with CATIP at F-actin rich zones and at dynamic plasma membrane protrusions.
Protein: CLSA_ECODH
Sequence: MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAPLFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIYSCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQDDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y749_STAAT
Sequence: MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMTHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
What is the function of this protein?
May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG).
What are the official names of this protein?
Putative lipid kinase USA300HOU_0749.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family.
Protein: METE_CAMJJ
Sequence: MKNSIISYPRIGANRELKFAIEKYFKNQSSKEELLKSAKDLRIRHWQEIQKAGIDFIPSNDFSLYDNVLDAAVLFNIVHTKYKNLNLDALDEYFAQSRGYQGENGDVTALAMKKWFNTNYHYLVPECDNADIIALTGDKIFKEYLEAKELGIESKPVLIGIFTLFKLIAFKDEKTQKLAKEKLLNAYIELFDKLNELKVTWLELDEPYLVYDLSKEDIALFEEFYQELLNHKKDLKILLQSYFGDLRDIYPKLLESKFDALGLDFIEGKQSLALIQKYGFAKDKILFAGLINGKNIYANDYAKSLKLIKELQKYTQNIVLNTSCSLLHVPYSTEFESKLDSSYLKLFAFAKEKLQELKDLKEILNSSEENPLFRANQELFKNIPERLDEKVKARLKALKKEDFTRTPSFKERALIQKEFLKLPLLPTTTIGSFPQSTDVRSNRLAFKQEKISAQNYTEFNQQKIKECIQIQEEIGLDVLVHGEFERNDMVEYFGENLKGFLFTQNGWVQSYGTRCVKPPVIWGDVSRTKPITLAWSKFAQSLSQKIVKGMLTGPVTILNWSFPREDISLKESTEQIALAIRDEVLDLENAGIKIIQIDEAALREKLPLRKSDWHSEYLDWAIPAFNLVHSGVKAKTQIHTHMCYSEFGDILKEIDAMDADVISFEASRSNLSLLDTLKAIRFKTEVGPGVYDIHSPRVPSVEELSLTIEKILNKLPKEQIWINPDCGLKTRAYEEVIASLKNLVTATQKIREQL
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: LRPA1_HALS3
Sequence: MSTESTEERILAALEEDAQASYAAIAERADVSKPTVRKYIDQLESDGVIVGYSADVDPKKLSGQSIAMVGIDVASEQYVEATRTLQELDSVQALYSSSGDHMLMAEVRAADGDALGDVISDEVLAIDGVTAAHPSFLQERLK
What is the function of this protein?
Transcription factor that regulates genes involved in amino acid metabolism.  Represses the aspB3 gene, coding for an aspartate transaminase, in the presence of L-aspartate.  Another target gene is the basal transcriptional regulator tfbB.  Binds also its own promoter.
What are the official names of this protein?
HTH-type transcriptional regulator LrpA1.
Protein: Y1187_METJA
Sequence: MVKMRDKILGSVFGAVIGDALGMPTENLTKEEIKKLYGFVDSYVEPKNYLAGKLNKGEWTDDTEQAICLIKSLTKEGIDIKKFANCLIAWKNKNPPDIGLTSLMAIDKLENNDYSGVDSSSCGAAMRIYPLGIVFHNNLKKLKEEVIKASKITHNNKTAIAGALAIAFFVSSALKDRKDFSLLDECYNYIKDIDEEFAKKLLEIKNFNNLDYIYDYFGTGVKTDEVVPSAIATYLLTDNFKEGMLKCINAGGDTDSLASMYGAMAGAYYGFKNIPKEWIDGLKNKEVIFELAERLYHLATE
What are the official names of this protein?
Uncharacterized protein MJ1187.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family.
Protein: SYVM_PIG
Sequence: MPHLPLASFRPPLRGLRPTRCFPRSHSLSTQSEPHGSPISRRNREAKQKRLREKQAALETGIAAKGKPPAESTKAWTPKEIVLYEIPTEHGEKKDVSRPLPPAYSPRYVEAAWYPWWVREGFFKPEYQTRLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDRVLWVPGSDHAGIATQAVVEKKLWKERGLRRRELSREDFLREVWKWKEEKGGEICQQLRVLGASLDWDRECFTMDAGSSVAVTEAFVRLYKAGLLYRSRQLVNWSCALRSAISDIEVESRPLSGRTELRLPGCPTPVSFGLLVSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDARYTHLHGRQLHHPLTGQLLPLITDCAVQPHLGTGAVKVTPAHSPADAELGARHGLSPLSVIAEDGTMTSLCGDWLQGLHRFVAREKIVSALRERGLFRGLQNHPMVLPICSRSGDVVEYLLKSQWFVRCQEMGEQAAKAVVSGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHRIPAYLVVEERAKGNTEDCWVVGRTEAEAREVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWPQETPDLARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHSMVRDRQGRKMSKSLGNVLDPRDIINGVELQVLQEKLRDGNLDPAELAIAAAAQKKDFPHGIPECGTDALRFTLCSHGVLGGDLHLSVSEVLSFRHFCNKIWNALRFILNALGEKFIPQPLEELCPTSPMDAWILSCLARTAQECERGFLTRELALVTHALHHFWLHNLCDVYLEAVKPVLSHSPRPPGPPQVLFSCADVGLRLLAPLMPFLAEELWQRLPLRPGNTTAPSICVAPYPSAHSLEHWHQPELERRFSRVQEAVQALRALRATYQLTKARPRVLLQTSEPGEQGLFEAFLGPLSTLGHCGAVGFLPPGAAAPSSWAQASLSDTAQVYMELQGLVDPQTHLPRLAARRQKLQKQLDSLLARTPSEGEAESQSQQRLSSLQLELSKLDKAASHLRQLMDASPSPGEL
What are the official names of this protein?
Valine--tRNA ligase, mitochondrial, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RISB_SYNE7
Sequence: MAVFEGSFVNASQFRLAVVIGRFNDLVCEKLLAGCQDCLKRHGVDPDPQGTQVDYAWVPGSFEIPLVARQLALTGRYDAIICLGAVIRGQTPHFDYVASEVAKGVAATSLQTGIPIAFGVLTVDNLQQALERAGIKSNLGWNYALSALEMASLMHQIRSTTGEVPRQTLPLAAAPSNFAGT
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ENOPH_RAT
Sequence: MVVVSVPAEVTVILLDIEGTTTPIAFVKDILFPYIKENVKEYLQTHWEEEECQQDVSLLRKQAEEDAHLDGAVPIPVASGGDVQQMIQAVVDNVSWQMSHDRKTTALKQLQGHMWKAAFTAGRMKAEVFADVVPAVRRWREAGMKVYIYSSGSVEAQKLLFGHSTEGDILELIDGHFDTKIGHKVESDSYRKIADSIGCSTNNILFLTDVTVEASAAEEADVHVAVVVRPGNAGLTDDEKTYYNLISSFSELYLPSTQSKV
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase, MASA homolog.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.