PharMolix/UniProtQA huggingface dataset:
Protein: SYN2_LACPL
Sequence: MVQQINIIDAKDHVDEKVKIGAWLTNKRSSGKIAFLQLRDGSAFFQGVVVKSQVSEEVFELAKEVKQEASMWITGVIHEDSRSKFGYEIEVEDIVVVGESEEYPITPKEHGVDFLLDHRHLWLRSKRPWAIMNIRNEVIRGTYEFFNQEGFIKMDSPILTGSAPEGTTELFHTEYFDRDAYLSQSGQLYAEAGALAYGKVFTFGPTFRAEKSKTRRHLIEFWMIEPEMAFMHQEQSLEVQERYIAFLVQGVIDHCQYALDILGRDVETLKKYTKLPYPRISYDEAIELLKENDFDVDWGVDFGSPEETFLADHFDQPVFVLNYPKAIKPFYMKPHPTRDDVVICADLLAPEGYGEIIGGSERATDYNYLLDQIKQAGLNPDDYAWYLDLRKYGSVPHAGFGLGLERFLTWITAEDHVRETIPFPRLLNRIYP
What are the official names of this protein?
Asparagine--tRNA ligase 2, Asparaginyl-tRNA synthetase 2, AsnRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG01_EHV1H
Sequence: MRPEGVSRGRASSVSISMCPPPPNGARRASLGCAPPLNSRPVCCAPSSVSLSSSSSRRSMPSLGSSRSSSLPSTGSLRSITRDPERLPSRPPSYTAINPECLLERGAERPRAWTASVMTAPPSYSEALCQAPPAYELVPELSYHPTQDPRGVYSSRSDPHQTSRRRQNPICIFIIVVATMLLILGLLLTITLSSLTNGKKEK
What are the official names of this protein?
Uncharacterized gene 1 protein.
Protein: TRUA_BRUA2
Sequence: MPRYKLTVEYDGTPYVGWQRQENGHAVQGAIEQAFKKFCGEDLTLSAAGRTDAGVHATAQVAHVDLAKDWGAGKVRDAVNAHLVMADERISILNVEKTTDTFDARFSARARHYLYRIHNRRAPLAVDYQRAWWVQKQLDADAMHEAAQRLLGEHDFTTFRATQCQAKSPVKTLDRLDVTRNGDMVEMRVSARSFLHNQVRSFAGSLMEVGVGRWTADDLQAALEARDRKACGQVAPPYGLYLVGVDYAFPF
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: F117A_HUMAN
Sequence: MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPFQLQQPHQRRDGGGRAASVPCSVAPEKSVCRPQPLQVRRTFSLDTILSSYLLGQWPRDADGAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISKLKQQLQRTKLSRSGKEKERGSPLLGDHAVRGALRASPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEEPVLFQSSLMV
What are the official names of this protein?
Protein FAM117A, C/EBP-induced protein.
What is the protein family that this protein belongs to?
Belongs to the FAM117 family.
Protein: PYRR_CHLAA
Sequence: MGNEKQILSADEIRRALVRIAHEIDERNGGLRDVVLVGIRSRGVPLAERIAAAIADFEGTRIPVGQLDITLYRDDLKLRGPAPRVRKTDLPIDITGKTVVLVDDVLFTGRTVRAALDAIADLGRPARIQLAVLIDRGHRELPIRADFVGKNVPTSLSERVMVRLRETDGVDEVVILRGSAND
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: MOC2B_ASPFC
Sequence: MATQPPQDQTSTTPSLPPHLDPTTYPRILTSATHNIHLELTYSTLNPTVALEHTSSPAAGANVLFLGTTRDTFEGRAVSQLSYTSYPPLALKSLMSIATRAVEKFDLKGVYIAHRLGVVPISEASIVVAVSAGHRGMAWKAAEEVLEEVKEKVEIWKREEFVDGGMEWRENRERDAEGRILSSTEGGK
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Common component for nitrate reductase and xanthine dehydrogenase protein H, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T41AB_DANRE
Sequence: MRSIWGLIVLVAAATFYLYLLSAFLPPGPRAIRVHDTGPEHTDDEPEEKVLRLKFPSDLEELRELAELLKFYKTEHTGYVFILFCSAYLYKQSFAIPGSSFLNMLSGALFGPLHGLIIACTLTTVGSTNCYLLSRTFGKRHIVRLFPEKVAMLQRMVEENRSSLFFFLLFLRFFPMTPNWFLNVTSPILNIPIPIFFFSILIGLIPYNFICVHTGAVLSEINSLDDIFSWFTLLQLLLIACVALLPGALIRRYSKDHLKLHGLEPNGHQKILNDRKTR
What are the official names of this protein?
Transmembrane protein 41A-B.
What is the protein family that this protein belongs to?
Belongs to the TMEM41 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BPT_PSEE4
Sequence: MTELARLKFYATQPHSCSYLPDEQATTLFLDPSQPMDVHVYADLSEMGFRRSGDHLYRPHCQNCNACVPARIPAVRFIPNRQQRRILKRNADLTVSAVRPVFKEEYFDLYRRYIEQRHADGDMYPPSRDQFSTFLVRDLPFCWFYEFRLEGRLMAVAVCDLLPNGLSAVYTFYEPDEERRSLGRYAILWQITEALRQNLDAVYLGYWIKNCKKMNYKTQYRPIELLINQRWVTLN
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRBP1_RAT
Sequence: MDELPFGEAALEQALAEVCEMDAALLTDIEDMLQLINNQDSDFPGLFDAPYAGGETGDTGPSSPGASSPESFSSPASLGSSLEAFLGGPKVTPAPLSPPPSAPTAVKMYPSVPPFSPGPGIKEEPVPLTILQPPAPQPSPGTLLPPSFPPPPVQLSPAPVLGYSSLPSGFSGTLPGNTQQTPSSLPLGSTPGISPTPLHTQVQSSAAQQPPPASAAPRMSTVASQIQQVPVVLQPHFIKADSLLLTAVKTDTGATMKTAGINTLAPGTAVQAGPLQTLVSGGTILATVPLVVDTDKLPIHRLAAGGKALGSAQSRGEKRTAHNAIEKRYRSSINDKIVELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLTLRSAHKSKSLKDLVSACGSGGGTDVSMEGMKPEVVETLTPPPSDAGSPSQSSPLSLGSRGSSSGGSDSEPDSPAFEDNQVKAQRLPSHSRGMLDRSRLALCVLVFLCLTCNPLASLFGWGILTPSDASGVHRSSGRSMLEAESRDGSNWTQWLLPPLVWLANGLLVLACLALLFVYGEPVTRPHSGPAVHFWRHRKQADLDLARGDFAQAAQQLWLALQALGRPLPTSNLDLACSLLWNLVRHLLQRLWVGRWLAGQAGGLQRDYRLRKDARASARDAAVVYHKLHQLHAMGKYTGGHLVASNLALSALNLAECAGDAISMATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACLAQSGAVPLAMQWLCHPVGHRFFVDGDWAVHGAPQESLYSVAGNPVDPLAQVTRLFCEHLLERALNCIAQPSPGAADGDREFSDALGYLQLLNSCSDAVGAPACSFSVSSSMATTTGTDPVAKWWASLTAVVIHWLRRDEEAAERLYPLVEHIPQVLQETERPLPRAALYSFKAARALLDHRKVESSPASLAICEKASGYLRDSLASTSTASSIDKAMQLLLCDLLLVARTSLWRRQQSAASAQGAHGTSNGPQASALELRGFQHDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPARTHQLLDRSLRRRAGSSGKGGAAAELEPRPTWREHTEALLLASCYLPPAFLSAPGQRVSMLAEAARTVEKLGDHRLLLDCQQMLLRLGGGTTVTSS
What is the function of this protein?
Predominant isoform expressed in most tissues, which has weaker transcriptional activity compared to isoform SREBP-1A (By similarity).  Primarily controls expression of lipogenic gene (By similarity).  Strongly activates global lipid synthesis in rapidly growing cells (By similarity).
What are the official names of this protein?
Sterol regulatory element-binding protein 1, SREBP-1, Adipocyte determination- and differentiation-dependent factor 1, ADD1, Sterol regulatory element-binding transcription factor 1.
What is the protein family that this protein belongs to?
Belongs to the SREBP family.
What are the subcellular locations of this protein?
[Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane; Multi- pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=At high sterol concentrations, the SCAP-SREBP is retained in the endoplasmic reticulum. Low sterol concentrations promote recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi, where it is processed. SUBCELLULAR LOCATION: [Processed sterol regulatory element-binding protein 1]: Nucleus.
Protein: UPPP_STRPF
Sequence: MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKQNAQQEPAVTDLARMSYKTAFFIGCFQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSLU_ECOBW
Sequence: MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXCR1_HUMAN
Sequence: MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL
What is the function of this protein?
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor (PubMed:1840701).  Binding of IL-8 to the receptor causes activation of neutrophils.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:8662698).
What are the official names of this protein?
C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, CDw128a, High affinity interleukin-8 receptor A, IL-8R A, IL-8 receptor type 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL27_LEPCP
Sequence: MAQKKGGGSTRNGRDSQPKMLGVKAYGGQMVSAGSIIVRQRGTRFHAGTNVGMGRDHTLFALVDGTISFDVKGASNRKTVFVTPV
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GRPE_BACAN
Sequence: MEERNEQVVEEVKEAQVEEAVTPENSEETVEEKSEAALLQEKVDELQAKLTETEGRTLRLQADFENYKRRVQMDKQAAEKYRAQSLVSDILPALDNFERAMQVEATDEQTKSLLQGMEMVHRQLLEALNKEGVEVIEAVGKQFDPNEHQAIMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QPTR_HAEIN
Sequence: MKLTSPIFNDQQKRRAIIWLSFFHIFIIAASNYFVQIPFEITLKLTALGAANDFSFHSTWGTLTFPFIFLATDLTVRIFGAEDARKIIFVVMFPALIVSYVISVLFSESKFQGFESLTHFDLFVFRIAIASFAAYVVGQLLDVIVFNRLRQLKTWWVAPTSSMTFGSMADTFVFFSIAFYQSADPFMAEHWAQLGFVDYLFKLFIGIILFVPAYGVVLNVILRKLQMLVTERVPA
What is the function of this protein?
Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.
What are the official names of this protein?
Probable queuosine precursor transporter, Q precursor transporter.
What is the protein family that this protein belongs to?
Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DER11_MAIZE
Sequence: MSSPAEYYKSLPPISKAYGTLCFFTTVLVQLQILHPLFLYLDYPLVFKKFEIWRLLTSFFFLAPFSMKFGIRLLMIARYGVMLEKGAFDKRTADFLWMMIFGAISLLVLSIIPLFNSFFLGIPMVSMLLYVWSRENPNAQINIYGLVQLRSFYLPWAMLLLDVIFGSSLMPGLLGIMVGHLYYFFAVLHPLATGKSYLKTPKWVHKIVARFRIGMQANSPVRPPANGNSGSGVFRGRSYRLNQ
What is the function of this protein?
May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins.
What are the official names of this protein?
Derlin-1.1, ZmDerlin1-1.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SRP54_STAMF
Sequence: MVLDGVRKALSRFLSGKGDYERAVKEFIRDLQKELIKADVNVKLVLELTKKIRERALKEEPPPGITRREWFVNIVYEELSKFFGGDKKPDIKPKKKPWVMLLVGLQGSGKTTTAAKLAYYYKLEGYRVGLVAADTYRPAAYDQLKQLGEQIGVPVYGEPDNKDAVEIARRGVEYFVSRGFDIVIVDTAGRHHREEDLLREMREIAENIKPDEVVLVIDAAIGQQAHDLAKKFHEATPIGSIIVTKLDGTAKGGGALSAVAVTGATIKFIGTGEKIDELEVFRPPRFVARILGIGDLEGLIEKVRRIKVEFTEKDVEEFLSGRLNMRLVYKQLVSLRKMGPLRKILQMIPGLSLKIPLEIEAGKAEEKIKKWLAIINSMTYEELDKPEIIDRRRIRRIAYGAGVKPEDVRELLKQYEMMKKLSKQLRKRRDLLEKLQLGFKP
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: RL11_OPITP
Sequence: MAKKIQGYIRLQLPAGAANPAPPVGPALGAQGVNIMAFCKDFNARTKDQNGMILPVVITVYTDKSFTFILKSPPASVLLKKAANIATGSGKPNQDRVGKVTKKQCAEIWKLKKADMNAKDEAAGIKTIAGTARQMGIEVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: INHA_MYCS2
Sequence: MTGLLEGKRILVTGIITDSSIAFHIAKVAQEAGAELVLTGFDRLKLVKRIADRLPKPAPLLELDVQNEEHLSTLADRITAEIGEGNKIDGVVHSIGFMPQSGMGINPFFDAPYEDVSKGIHISAYSYASLAKAVLPIMNPGGGIVGMDFDPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAMSAIVGGALGDEAGQQMQLLEEGWDQRAPLGWNMKDPTPVAKTVCALLSDWLPATTGTVIYADGGASTQLL
What is the function of this protein?
Is the primary target of the first-line antitubercular drug isoniazid (INH) and of the second-line drug ethionamide (ETH) (PubMed:12406221, PubMed:10869086).  Overexpressed inhA confers INH and ETH resistance to M. smegmatis (PubMed:12406221).  The mechanism of isoniazid action against InhA is covalent attachment of the activated form of the drug to the nicotinamide ring of NAD and binding of the INH-NAD adduct to the active site of InhA (By similarity).  Similarly, the ETH-NAD adduct binds InhA (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR, Enoyl-ACP reductase, FAS-II enoyl-ACP reductase, NADH-dependent 2-trans-enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: SYFA_PLAVS
Sequence: MQAKAQEEQKGEELSQFLQALEEEFALCQEGGGDKREADGPSLENAEAEELANRRAYYLQLKEERNVLVEESKHVTSLHMSSKHNIEHAKVLGMAKKLETLYYVVNHVRSFNTYQLTEEGKEYLRDGSPEHVTLRYVMEQEGCTLEDLKKLFGKKGEIGLNINLKKKKIELRKSDKRLFPHVEGSAHSLVDETRCYLQKVEAHGNDEGALVSHLKGILPPEKGEKKEEDEANNLIKELKKRKLIEAKKISYIYIIRTNLFTKEIKKQITDLTYLLIKNEEYKKYQVKKYNFFSSGKKMNKGNIHLLIRQMRTFKDVFVSLGFEEMNTHNYVESSFWCFDALYIPQQHPSRDLQDTFFIKVPEMCQEEFTDQSYIENVKRVHSVGDYGSFGWNYQWELKSTKKNVLRTHTTANSCRALFQLAKEYQKTGSIIPKKFFSIDRVFRNENLDSTHLAEFHQVEGLIIDRNLGLSHLIGTLSAFYKYIGISKLRFKPTFNPYTEPSMEVYGYHEENKKWLEVGNSGIFRPEMLRAMGFPPEVSVIAWGLSLERPTMIKYSIRNIRDLFGYRSVI
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanine tRNA-synthetase alpha subunit, FRS, PheRS, Phenylalanyl-tRNA synthetase alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RUVC_CHLAB
Sequence: MIMGIDPGTLVSGYAIILVEQRYKIRAHSYGAIRLSSKDSLTQRYKQLFQTLSGVLDNVTPDAVVLETQYVHKNPQSAIKLGMGRGVLVLAAALRDIPVFEYTPNVAKRAVVGKGNASKQQVQLMVSKILNIPDVLNSDCEDIADAFALAICHAHTSAYTCLGVR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: UTP7_YEAST
Sequence: MGHKKNGHRRQIKERENQNKFERSTYTNNAKNNHTQTKDKKLRAGLKKIDEQYKKAVSSAAATDYLLPESNGYLEPENELEKTFKVQQSEIKSSVDVSTANKALDLSLKEFGPYHIKYAKNGTHLLITGRKGHVASMDWRKGQLRAELFLNETCHSATYLQNEQYFAVAQKKYTFIYDHEGTELHRLKQHIEARHLDFLPYHYLLVTAGETGWLKYHDVSTGQLVSELRTKAGPTMAMAQNPWNAVMHLGHSNGTVSLWSPSMPEPLVKLLSARGPVNSIAIDRSGYYMATTGADRSMKIWDIRNFKQLHSVESLPTPGTNVSISDTGLLALSRGPHVTLWKDALKLSGDSKPCFGSMGGNPHRNTPYMSHLFAGNKVENLGFVPFEDLLGVGHQTGITNLIVPGAGEANYDALELNPFETKKQRQEQEVRTLLNKLPADTITLDPNSIGSVDKRSSTIRLNAKDLAQTTMDANNKAKTNSDIPDVKPDVKGKNSGLRSFLRKKTQNVIDERKLRVQKQLDKEKNIRKRNHQIKQGLISEDHKDVIEEALSRFG
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 7, U3 snoRNA-associated protein 7, U three protein 7.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: IORB_ARCFU
Sequence: MRLNIVVVGVGGQGALTTSGIIARAAMRAGLNVVTAETHGMAQRGGSVEVHVRIGDVRAPLIPEGGADVMIALEPAEALRYAKFLNKNTLVILNTRKIIPPSVTAGTAKYPELDEIIGELRKVTPRVIPVNASEIAEKAGSVLATNVVVVGMLFGYYSMPFGIEHVEEAIRETMKSKIVDLNLKALKMGYNQAISGRPSAV
What is the function of this protein?
Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
What are the official names of this protein?
Indolepyruvate oxidoreductase subunit IorB, IOR, Indolepyruvate ferredoxin oxidoreductase subunit beta.
Protein: MAO2_SALTY
Sequence: MDEQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVAAPCLEIEKDPLAAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFAGIDVFDIEVDELDPDKFINVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFHDDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGMQKHNIVVCDSKGVIYKGREPNMAETKAAYAVDDSGKRTLDEVIDGADIFLGCSGPKVLTQEMVKKMARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDVGATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKIAPAVAKAAMDSGVATRPIADFDAYIDKLTEFVYKTNLFMKPIFSQARKDPKRVVLPEGEEARVLHATQELITLGLAKPILIGRPSVIEMRIQKLGLQIKAGVDFEIVNNESDPRFKEYWSEYYQIMKRRGITQEQAQRAMIGNHTAIGAIMVQRGEADAMICGTIGDYHEHFSVVKAVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNEDPTPEQLAEIAVMAAETVRRFGIEPKVALLSHSNFGSSNSLSASKMRETLERVRERAPDLMIDGEMHGDAALVESIRNDRMPDSPLKGAANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVSKPVHVLTPIASVRRIVNMVALAVVEAQTTPL
What are the official names of this protein?
NADP-dependent malic enzyme, NADP-ME.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
Protein: RL14_LACH4
Sequence: MIQNESRLKVADNSGARELLVIRVLGGSKRKTGNIGDIVVCTVKQATPGGVVKKGDVVKAVIVRTKSGARREDGSYIKFDENAGVIINADKSPRGTRIFGPVARELREYDFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: UVRC_DEHMC
Sequence: MPNETLQNQIASLPENPGVYLMKNAQGEIIYVGKAAVLKDRVKSYFVPPSRLTPKTCQLVSQINELEYLITGSEQEALILELNLIKRHRPYFNVRLKDDKGFPYLKITLNEKWPRIYITRSMADDGGRYFGPFANTRSVRHTLQVLKELFRFRSCNRTEPEKHSRPCLEYDIHQCLSPCTGKISKSDYDHLISQAILFLEGKQDQVLKLLIRLMNEASARLDYETAALRRDQIASIKEVIEGQQLAARVTGEQDAIAFAQEGDLSMVQVFFIRRGKLIGRESFCLQGTREEKPGDILSEFAKQFYHSSTQIPPKIVTQYPVSDREILEKWLSQRRGDKVHITAGLRGQPKELINIVAENAREQLKQARIKNLSSSVTLTDALAELQTALGLSLPPQRIEGYDISNIQGTNAVGSMVVFENGKPQKAHYRRFRIKTVKGADDFSMLKEVISRRFGRVHREDAGESFARLPSLMLIDGGKGQLSSVKETLDKLGLEGQAVIGLAKEFEEIYLPHKSEPIRLAANSPALQLLQRVRDEAHRFALGYHLHIRQKSGLTSALDGIPGVGPSRRRLLIKTFGSVAGIRQASFEKLSQVKGINQALALSIKELL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVSSA_CAEEL
Sequence: MLKRRQPKYCSFMDSIDNSTTIIRKNLNRFIRELTDDGKLDFESIPYQNLQKEVANQDEEGCENVIEVLLDTTSRSGCPDRKLILQLFNSFFLQFPIFRENLLNDPSEFLELMFETNPIRNPLPGSKKHGNELKVEAITVIKSWEKEKCVKNDARMKCLVVTLKKTKFVDYENGAKKIEAERKRKKILEERKMKMIENSVNVYSSKYHEIKNDAETLSMELTTTMQMLVPSFTTADPEVPSTSTSTPSAISDSKSFEIFIPDLTPEISVSSENDAIVEAFLGAKLSLIHRVQTLRKLVKRLQLLKQPGEKLAQEIIDYRDGIKNLVLKADELRIINPRPPKNKRKKSDDDFIDVDISIDDILMVQYAEKLEVDVKSKDESEKITESPEKHKIEMKNEKPVKIKTVPFGLDLKYWGEERKDVEVPKNNADCHRFWRSADEGTVAGKAQQSIYTQRQYTFIGKAPDNRKVCLAKMKSGKLCPRKDYYTCPLHGKIVDRDDEGRPINEEDRLEENYRKEQNHLKEADKIRQMIEKEYESKTKRRKKHDVDTTASEDVRNRLQKKLLDPKTIQRVSADLDASRKNRLEKNFGQQFSHF
What is the function of this protein?
Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage (PubMed:27043179).  TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes (By similarity).
What are the official names of this protein?
UV-stimulated scaffold protein A homolog.
What is the protein family that this protein belongs to?
Belongs to the UVSSA family.
What are the subcellular locations of this protein?
Chromosome. Note=Accumulates at UV DNA damage sites.