PharMolix/UniProtQA huggingface dataset:
Protein: VELB_GIBM7
Sequence: MNSAYHPPDMSQRIPGPAYSSSAPPPIHTYQQHQHPPPPLPPPSQHHHSSHPPLPPPPSAPHPHHQHPPPPPSHSLSSHQHHGQPPHHQPQPYAPAPYQQSQPSQYPRPHPHQQHVPPPSQHDEPPPPPSSGPSPTDHQKDSEYVPPSYSKIEEGSGWKYSLDVKQQPVRARMCGFGDKDRRPITPPPCVRLVIINTETGKEVDYNTLDHAMFVLSVDLWNHDEPGTPSYQQQSLPPSRESGYGQSQGMNYGQDYPPPVQQSYGPAPSYPPSSSYGPPQQYYPRHSGYSAEPSAPPPGAPFRNGYGQDQNALTRMAVVGGQPQGMFTRNLIGSLAASAFRLEDTEGQSGIWFVLQDLSVRTEGTFRLRFSFVNVGRPGGQGTNVNQGRAPILSSCYSESFHVYSAKKFPGVCESTPLSKKFANQGIKIPIRKDANIKGEGDEEMYDQN
What is the function of this protein?
Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (PubMed:24792348).  The velvet complex acts as a global regulator for secondary metabolite gene expression (By similarity).  Component of the VELB-VOS1 heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity).  The VELB-VOS1 complex binds DNA through the DNA-binding domain of VOS1 that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity).  Controls the expression of the fumonisins gene cluster (PubMed:24792348).  Involved in cell wall integrity, cell surface hydrophobicity, hyphal polarity and conidiation pattern (PubMed:24792348).  Involved in oxidative stress resistance by positively regulating the transcription of the catalase-encoding gene CAT2 (PubMed:24792348).
What are the official names of this protein?
Velvet complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VelB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear localization is mediated by VE1 (By similarity).
Protein: LIPB_ACIAD
Sequence: MNDTVLKPNLIIRHYKNLHNYASLFQEMRSYTDQRDEHSPDQLWILQHHPVLTQGQAGKPEHILIPSDLPVVQSDRGGQVTWHGPGQMVIYFMFDLNRLKWNVRTLVSFAEQLMIDLIKKYNIDAYAKADAPGVYVAERKIGSLGFKIRRGRSYHGLALNIDCDLSGFQTINPCGYAGLEMVRICDLVENYPRFDQLAQDVTAYFKEKSDFNDVQVILQ
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_CALBD
Sequence: MLNFSDRLIESIKKKNSVLIAGIDTSIENIPDYFIKRFYDKEKSEIDNLKTILFEYIRRIIDAVEENVVGVKFQAAFFEQYSYHGFEVLHKLCEYTKNKKLVVIFDGKRNDISSSAKGYSNAYLGETPVFGKKMRFFEFDAITTNPYLGQDGIKPFVEDCERFKKGLFVLVKTSNPSSADFQDLMVEDKYLFEVVAEKVYEWGKNCIGKEGYSDVGAVVGATQPEAAKRIREILPNSFFLVPGIGVQGGKIEDLKYFVDSNNMGIIVNSSRDIIYAYKNYVHSDFEKSSYLASKNIKESINAAIS
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: LTP2_MYCTU
Sequence: MLSGQAAIVGIGATDFSKNSGRSELRLAAEAVLDALADAGLSPTDVDGLTTFTMDTNTEIAVARAAGIGELTFFSKIHYGGGAACATVQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENADSTGVDNSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPKAYFYGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADGAIEVGGRLPINTHGGQLGEAYIHGMNGIAEGVRQLRGTSVNPVAGVEHVLVTAGTGVPTSGLILG
What is the function of this protein?
Involved in cholesterol side chain degradation (PubMed:22045806, PubMed:29109182).  When associated with the ChsH1/ChsH2 hydratase, catalyzes the retroaldol cleavage of 17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA (17-HOPC-CoA) produced by the hydratase, forming androst-4-ene-3,17-dione and propionyl-CoA (PubMed:29109182, PubMed:31568719).
What are the official names of this protein?
17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA lyase, Retro-aldolase Ltp2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily.
Protein: LGT_CAMJ8
Sequence: MEFWQHIYSNFNVIAFSIFGLKVHWYGIMYVIALLLALLLAKFFVRKFQLDINEKHLDSYFIWVEIGVILGARLGYILIYDANTMYYITHPWQIFNPYINGEFVGIRGMSYHGAIIGFLIATLLFCKKYKTNPWIFLDLVALSVPLAYVFGRIGNFLNQELFGRITNVPWGIYVDGVLRHPSQLYEAFLEGIVVFIIVYLARFKQSFQGELILVYAGAYSLARFICEFYREPDFGIGFVLWGMSMGQILSFIMFITALLVYICIKFKKVNI
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACT_KLULA
Sequence: MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKNNREKMTQILFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDITDYLMKILAERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTASQSSAVEKSYELPDGQVITIGNERFRAPEALFHPSVLSLEAAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHLKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HTPG_HELPH
Sequence: MSNQEYTFQTEINQLLDLMIHSLYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLNITPSIHLSFDSQKKTLTIKDNGIGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIGQFGVGFYSAFMVASKIVVQTKKVTNHQAYAWVSDGKGKFEISECVKEEQGTEITLFLKEEDSHFASRWEIDGIVKKYSEHIPFPIFLTYTDTKFEGEGDHKKEVKEEKCDQINQASALWKMNKSELKDKDYKDFYQSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSKAPFDMFRVDYKSGVKLYVKRVFITDDDKELLPSYLRFVKGVIDSEDLPLNVSREILQQNKILANIRSASVKKILSEIERLSKDEKNYHKFYEPFGKVLKEGLYGDFENKEKLLELLRFYSKDKEKLISLKEYRENLKENQKSIYYLLGENLDLLKASPLLEKYAQKGYDVLLLSDEIDAFVMPGVNEYDKTPFRDASHSESLKELGLEEINDEVKDQFKDLMKAFEENLKDEIKGVELSSHLTSAVALIGDEQNAMMANFMRQMGQSVPESKKTLELNPNHAILQKLLKCEDKEQLSAFIWLLYDGAKLLEKGALKDAKSFNERLNSVLLKAL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_SYNSC
Sequence: MSQSPHVTVLGAGLAGTEAAWQVARAGVAVTLVEMRPIRRSPAHHSSDFAELVCSNSFGALSSDRAAGLLQEELRRLGSLVIGTADTHAVPAGGALAVDRGRYSAALTEALDQHPLVTIERREQQNLPPENAITVLATGPLTSEPLAEDLRQFTGRADCHFFDAASPIVHGDSIDLSVAFRASRYDKGDADYINCPMDKEQYLAFRQALLEAEQAELKDFDKNDATFFEGCLPIEELARRGEDTMRYGPLKPIGLWDPRWGDVNDRDVRRAKRAYAVVQLRQEDKDGRLWNLVGFQTNLKWGEQKRVLQMIPGLGQAEFVRFGVMHRNTFLESPQLLQPTLQFRQRPNLLAAGQITGTEGYAAAVAGGWLAGTNAARLALGLEPIDLPATCMSGALTHFVSEAPTAKFQPMPPNFGLLPDLPERIRDKRARYGAYRDRALQDLEPMRALQPETVTA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLF18_MOUSE
Sequence: MMDRYSFIMHQHRDDTVWCPSKIEEQNITRISEFHLMGLSDDLQLQPILFGLFLSMYLVTLLGNLLIILTVSSDSHLHSPMYFFLSNLSLADVSFTSTTLPKMIVDIQTHNRAISYSGCLTQMSFFMLFGCLDSLLLTAMAYDRFVAICHPLHYQFIMNPRLCGLLVFLSVLISLFVSQLHNSVVLQLTYFKSVDISHFFCDPSQLLNLACSDTFTNNIVMYFVGAISGFLPISGIFFSYYKIVSSILRMPSPGGKYKAFSTCGSHLSVVCLFYGTGLGVYLSSAVSLSPRKGAVASIVYTVVTPMLNPFIYSLRNQDIKRAMWRLLRKTV
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 18, Olfactory receptor 145-1, Olfactory receptor TPCR34.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLPHP_HELPY
Sequence: MLDYRQKIDALITKIEKARTAYSRHHIVKIVAVSKNASPEAIQHYYNCSQRAFGENKVQDLKTKMHSLEHLPLEWHMIGSLQENKINALLSLKPALLHSLDSLKLALKIEKRCEILGVNLNALLQVNSAYEESKSGVVPEEALEIYSQISETCKHLKLKGLMCIGAHTDDEKEIEKSFITTKKLFDQIKNASVLSMGMSDDFELAIACGANLLRIGSFLFKE
What is the function of this protein?
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
What are the official names of this protein?
Pyridoxal phosphate homeostasis protein, PLP homeostasis protein.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
Protein: TRUA_RICRO
Sequence: MYRYKITIEYLGTDLAGWQRQAGVMSVQQILEEAIYKFSGEQVILFGAGRTDAGVHAVGQVAHFDLSKYLEPHKIITAINYFVRPYAVGVWNCELAPNNFHARFSATSRYYIYRIINRPYPSVIDLNRAWWISSPLDVPAMQQAAAYLLGKHDFTSFRASSCQSKSPIKTLTELNIIKEDEEIKLYLSAPSFLHHMVRNIVGSLVLVGKNIWQAEQIKDVLEAKDRKAAGPTAPASGLYFVKAAY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TDH_VIBCM
Sequence: MKIKALSKLKPEQGIWMNEVDMPELGHNDLLIKIKKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVRGFQIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRTGCFSEYLVIPAFNAFKIPDGISDDLASIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVAKHVGARHVVITDVNEYRLDLARKMGVTRAVNVAEQNLEDVMKELGMTEGFDVGLEMSGVPSAFSAMLKTMNHGGRIALLGIPPSSMAIDWNQVIFKGLVIKGIYGREMFETWYKMASLIQSGLDISPIITHHFKVDDFQKGFDIMRSGASGKVILDWQ
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLFA_STAAE
Sequence: MNMKKKEKHAIRKKSIGVASVLVGTLIGFGLLSSKEADASENSVTQSDSASNESKSNDSSSVSAAPKTDDTNVSDTKTSSNTNNGETSVAQNPAQQETTQSSSTNATTEETPVTGEATTTTTNQANTPATTQSSNTNAEELVNQTSNETTFNDTNTVSSVNSPQNSTNAENVSTTQDTSTEATPSNNESAPQSTDASNKDVVNQAVNTSAPRMRAFSLAAVAADAPAAGTDITNQLTNVTVGIDSGTTVYPHQAGYVKLNYGFSVPNSAVKGDTFKITVPKELNLNGVTSTAKVPPIMAGDQVLANGVIDSDGNVIYTFTDYVNTKDDVKATLTMPAYIDPENVKKTGNVTLATGIGSTTANKTVLVDYEKYGKFYNLSIKGTIDQIDKTNNTYRQTIYVNPSGDNVIAPVLTGNLKPNTDSNALIDQQNTSIKVYKVDNAADLSESYFVNPENFEDVTNSVNITFPNPNQYKVEFNTPDDQITTPYIVVVNGHIDPNSKGDLALRSTLYGYNSNIIWRSMSWDNEVAFNNGSGSGDGIDKPVVPEQPDEPGEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSSDSDSESDSNSDSESGSNNNVVPPNSPKNGTNASNKNEAKDSKEPLPDTGSEDEANTSLIWGLLASIGSLLLFRRKKENKDKK
What is the function of this protein?
Cell surface-associated protein implicated in virulence.  Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen.  Induces formation of bacterial clumps, which diminish the ability of group IIA phospholipase A2 to cause bacterial phospholipid hydrolysis and killing.  Significantly decreases macrophage phagocytosis possibly thanks to the clumps, clumped bacteria being too large to be phagocytosed.  Dominant factor responsible for human platelet aggregation, which may be an important mechanism for initiating infective endocarditis.  Enhances spleen cell proliferative response in vitro, contributing significantly to the immunostimulatory activity of S. aureus.
What are the official names of this protein?
Clumping factor A, Fibrinogen receptor A, Fibrinogen-binding protein A.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Found in a ring-like distribution on the surface (PubMed:18800056). Anchored to the cell wall by sortase A (By similarity).
Protein: GREB_SALTI
Sequence: MKTPLITREGYETLKQELNYLWREERPEVTKKVTWAASLGDRSENADYQYNKKRLREIDRRVRYLTKCMENLKIVDYSPQQEGKVFFGAWVEIENDDGDTLKFRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPVGEANWYVNAIEYVK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreB releases sequences of up to 9 nucleotides in length.
What are the official names of this protein?
Transcription elongation factor GreB, Transcript cleavage factor GreB.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family. GreB subfamily.
Protein: TYSY_SHIFL
Sequence: MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGVKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_PHEZH
Sequence: MGQKINPVGLRLGINRTWDSRWFADGPEYGRLLHEDIKVRRALKKRLYQAGVSRIIIERPHKKCRITIYAARPGVIIGKKGADIEKLRKDVAAMTDGEVHLNIVEIRKPETDAQLIAENIAQQLERRVAFRRAMKRSMQSAMRLGAKGVRINVSGRLGGAEIARMEWYREGRVPLHTLRADVDYGFTEAKTTYGVIGVKVWVFKGEVLEHDPMALDKRLAGESGPAGEGGGRERGDRPDRGPRRERRGEPSNA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NADD_CYTH3
Sequence: MKIGLFFGSFNPIHVGHLIIGNTMAETTDLDEVWYVVSPQNPFKKNQSLLHEFDRFDMVTAAIANNPKFRASDIEFSLPKPSYTVDTLTYISDKYPQHSFVLIIGEDNLDQFTNWKNHEQILHHYSLYVYPRPDSSNSFLREHKNVRLVAAPLLEISATYIRNLVKQEKSIRYLVSKEVEELILSRKYYSNY
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: YACG_LEGPH
Sequence: MNNQQKIKCPICDKQNTWRPDNLFRPFCSERCKLIDLGEWASESRKIPGSSIDPESIVTTNNKQDNVDEQ
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: METXA_LEIXX
Sequence: MDWQTTSADTAPSSFITEEQDRSLFGKPPASGAWKESDPVGGRRFAGIGAFGFESGESLPFVRIAYETWGELSPARDNAVLVLHALTGDSHAVGAAGPGHRTSGWWQGIIGPGKAIDTDRWFVAVPNMLGGCQGTTGPTSIAPDGAEWGARFPFTTIRDQVKAQAAFADALGIGRWAAVVGGSMGGMQALEWAVGFPERVERLAVIAAPPHSTADQIAFNSVQLGAIRTDPLFHGGSYYDEKDGEGPHQGLALARRMALITYRSLSELNDRFERTWQSGISPLGDGGRFAVESYLDFHGNKFTRRFDANSYLTLVQAMNSHDVGHDGSGLAAALSRVTATTLVVGIDSDRLFPVDGQELIASHLPAALDGRVPLVVRSHFGHDGFLIEDDLIGGQLRRLFAA
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCN2A_HUMAN
Sequence: MAQSVLVPPGPDSFRFFTRESLAAIEQRIAEEKAKRPKQERKDEDDENGPKPNSDLEAGKSLPFIYGDIPPEMVSVPLEDLDPYYINKKTFIVLNKGKAISRFSATPALYILTPFNPIRKLAIKILVHSLFNMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSSFEINITSFFNNSLDGNGTTFNRTVSIFNWDEYIEDKSHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAASAESRDFSGAGGIGVFSESSSVASKLSSKSEKELKNRRKKKKQKEQSGEEEKNDRVRKSESEDSIRRKGFRFSLEGSRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRASLFSFRGRAKDIGSENDFADDEHSTFEDNDSRRDSLFVPHRHGERRHSNVSQASRASRVLPILPMNGKMHSAVDCNGVVSLVGGPSTLTSAGQLLPEGTTTETEIRKRRSSSYHVSMDLLEDPTSRQRAMSIASILTNTMEELEESRQKCPPCWYKFANMCLIWDCCKPWLKVKHLVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISNDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDFVKRKIREFIQKAFVRKQKALDEIKPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESDMEESKEKLNATSSSEGSTVDIGAPAEGEQPEVEPEESLEPEACFTEDCVRKFKCCQISIEEGKGKLWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQVYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINYTTGEMFDVSVVNNYSECKALIESNQTARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEMTNILYWINLVFIVLFTGECVLKLISLRYYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGPPDCDPDKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFAKLSDFADALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYEPITTTLKRKQEEVSAIIIQRAYRRYLLKQKVKKVSSIYKKDKGKECDGTPIKEDTLIDKLNENSTPEKTDMTPSTTSPPSYDSVTKPEKEKFEKDKSEKEDKGKDIRESKK
What is the function of this protein?
Mediates the voltage-dependent sodium ion permeability of excitable membranes.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:1325650, PubMed:17021166, PubMed:28256214, PubMed:29844171).  Implicated in the regulation of hippocampal replay occurring within sharp wave ripples (SPW-R) important for memory (By similarity).
What are the official names of this protein?
Sodium channel protein type 2 subunit alpha, HBSC II, Sodium channel protein brain II subunit alpha, Sodium channel protein type II subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.2.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.2/SCN2A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IHFB_XANCB
Sequence: MTKSELIEILARRQAHLKSDDVDLAVKSLLEMMGQALSDGDRIEIRGFGSFSLHYRPPRLGRNPKTGESVALPGKHVPHFKPGKELRERVSSVVPVDMVDAAD
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: O11H4_HUMAN
Sequence: MSFFFVDLRPMNRSATHIVTEFILLGFPGCWKIQIFLFSLFLVIYVLTLLGNGAIIYAVRCNPLLHTPMYFLLGNFAFLEIWYVSSTIPNMLVNILSKTKAISFSGCFLQFYFFFSLGTTECLFLAVMAYDRYLAICHPLQYPAIMTVRFCGKLVSFCWLIGFLGYPIPIFYISQLPFCGPNIIDHFLCDMDPLMALSCAPAPITECIFYTQSSLVLFFTSMYILRSYILLLTAVFQVPSAAGRRKAFSTCGSHLVVVSLFYGTVMVMYVSPTYGIPTLLQKILTLVYSVTTPLFNPLIYTLRNKDMKLALRNVLFGMRIRQNS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 11H4, Olfactory receptor OR14-36.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ORF9B_BCHK3
Sequence: MDPKVNVVPPALHLVDPQIQMTITRMEDAVVHDQNNAGPKVYPIILRLGSQLSLSMAKRNLDSLEARAFQSTPIVVKMTKLATTEELPDEFVVVTAK
What are the official names of this protein?
Protein 9b, Accessory protein 9b, ORF-9b.
What is the protein family that this protein belongs to?
Belongs to the coronavirus group 2 protein 9b family.
What are the subcellular locations of this protein?
Host cytoplasmic vesicle membrane; Peripheral membrane protein. Host cytoplasm. Note=Binds non-covalently to intracellular lipid bilayers.
Protein: PR6A1_RAT
Sequence: MVKSWLRMSKKMEAGTLLMLLMSNILLWENVASVPRHASGAGRGEMSLHGLLDHAIILAHNVTELIAEMNSVFLEDVLYKPGRWFPERDLTACHRSPFTIAVSKEGTQQRLGVFLVKEMIGMLETWTFSLYHIANEMSHMEEPPDEIISRAKNIEEKIKELMDVLKGILNKIQPGSPQNERFPMWNELAYLRSPDEERRHFAFTNLFQCLLQDSRKFDSKVRLLKCRLIYNRDC
What are the official names of this protein?
Prolactin-6A1, Placental prolactin-like protein B, PLP-B, PRL-like protein B.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: WHIA_STRP3
Sequence: MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSITTENAKIARYIYSFIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADSFFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQLMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDINRANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQVADALEFPITKSGVNHRLRKINKIADDL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.