PharMolix/UniProtQA huggingface dataset:
Protein: ATP6_PROMA
Sequence: MGTSPFVLPFAALEVGQHLYWQIGKLRIHGQVFMTSWILIGALLTLVVVGTKKMERDPKGVQNLLEFLWDYIRDLARTQIGEKVYRDWMPFIGTLFLFIFVSNWGGALIPWKLIELPSGELGAPTADINTTVALALLVSLSYFYAGLSNKGLRYFEYYVHPTPIMLPFKIVEDFTKPLSLSFRLFGNILADELVVAVLVFLVPLVLPVPVMFLGLFTSAIQALIFATLAAYYIGEAVEEHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: GCSH_ORYSI
Sequence: MALRLWASSAANALKISCSGATRAAPAYSISRYFSTVLDGLKYSSSHEWVKNDGSVATIGITDHAQGHLGEVVFVELPEAGAKVSQGGAFGNVESVKATSDINSPISGEVVEVNDKLSETPGLINSSPYEDGWMIKVKPSSPSELDALLDPAKYTKHCEEEDAH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity).
What are the official names of this protein?
Glycine cleavage system H protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PFS47_PLABA
Sequence: MKGFTGASIIVFYLIKGYLSYIIFPNGYVCDFKFNPLVNVLPSINTTGDIEEVGCTINNPSLSDYIALVCPKKNYNDYEHMEKVPSKCFSSNLYSPYKSEDSAHKLEELKIPEKYSISKDFSDFDLNIILIPSLYNIDKTIYCRCDNSKTKRELIKNDGENIKLQGKLGLVKIILNNQQNSPQNIYHITRSTQVGSLDNKVIELKEGEIVHLKYDGKTRTNFNCKEIINMKISIPLDYNLSMRMPTVFLKDINCKFHLIFSNVGGIANIVFKAKKTENIDGCDFTVPKGKGLYKNGFALSEINNDEEICTVHIGRGQNSNAAGLKCPYNLTPAHCFKHVLYEKKYKNGNNVFQTFLLDDVLRTVDIEYYYNAKLSAHIVGIPTIPEKSETVRCVCEHDGKKGIMELKISSSKNIFISFILLSIIVSIFYLF
What is the function of this protein?
Required for female fertility.
What are the official names of this protein?
Female gametocyte surface protein P47.
What are the subcellular locations of this protein?
Cell surface. Cell membrane; Lipid-anchor, GPI-anchor. Note=Specifically present on the surface of female gametocytes.
Protein: HACDA_ORYSJ
Sequence: MAGVGSAVRRLYLSVYNWAVFFGWAQVLYYAVTTLLESGHEAVYAAVERPLQFAQTAAFLEILHGLVGLVRSPVSATLPQIGSRLFLTWGILWSFPETHSHILVTSLVISWSITEIIRYSFFGMKEAFGFAPSWLLWLRYSTFMVLYPTGISSEVGLIYIALPYMKASEKYCLRMPNKWNFSFDFFYASILSLAIYVPGSPHMFTYMLAQRKKALAKAKAA
What is the function of this protein?
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation.  Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.  May be an anti-phosphatase that prevents CDKA-1 dephosphorylation and activation.  Involved in the hormonal control of cell division and differentiation.  Required for proliferation control of meristematic and non-meristematic cells.  Negative regulator of the cell cycle.
What are the official names of this protein?
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2A, 3-hydroxyacyl-CoA dehydratase PASTICCINO 2A, HACD, PAS2A, Protein tyrosine phosphatase-like protein.
What is the protein family that this protein belongs to?
Belongs to the very long-chain fatty acids dehydratase HACD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GLY1_CANAX
Sequence: MTADEEETFTTFNEFRSDTFTVPTRAMVEDGFMNATFGDSVYQEDETTLRLESKMCEITGKPAALFCVSGTMSNQIGLRANLVQPPYSILCDYRAHVFLHEAGGLATLSQAMVHPVRPSNGNYLTFEDVLGNVTYDDDGDIHAAPTKVISLENTLHGIIIPIEEIRKISEFCRENDIRLHLDGARLWNASVATGISIKEYCSYFDSVSLCLSKSLGAPIGSVLVGDEKFIRKANHFKKQSGGGIRQAGIMSAMAIHAIDYNLSKLELSHNYAKQIGDFCQEHGIKLESPVDTSLVFLDLKANKMDPNRLVELGRTKYNVKLMGQRIACHFQLSQESVDNVKKCILECLEYHQKHPHKDDGRNNKKMYSLDAIKK
What are the official names of this protein?
Low-specificity L-threonine aldolase.
What is the protein family that this protein belongs to?
Belongs to the threonine aldolase family.
Protein: PIC_SHIFL
Sequence: MNKVYSLKYCPVTGGLIAVSELARRVIKKTCRRLTHILLAGIPAICLCYSQISQAGIVRSDIAYQIYRDFAENKGLFVPGANDIPVYDKDGKLVGRLGKAPMADFSSVSSNGVATLVSPQYIVSVKHNGGYRSVSFGNGKNTYSLVDRNNHPSIDFHAPRLNKLVTEVIPSAVTSEGTKANAYKYTERYTAFYRVGSGTQYTKDKDGNLVKVAGGYAFKTGGTTGVPLISDATIVSNPGQTYNPVNGPLPDYGAPGDSGSPLFAYDKQQKKWVIVAVLRAYAGINGATNWWNVIPTDYLNQVMQDDFDAPVDFVSGLGPLNWTYDKTSGTGTLSQGSKNWTMHGQKDNDLNAGKNLVFSGQNGAIILKDSVTQGAGYLEFKDSYTVSAESGKTWTGAGIITDKGTNVTWKVNGVAGDNLHKLGEGTLTINGTGVNPGGLKTGDGIVVLNQQADTAGNIQAFSSVNLASGRPTVVLGDARQVNPDNISWGYRGGKLDLNGNAVTFTRLQAADYGAVITNNAQQKSQLLLDLKAQDTNVSEPTIGNISPFGGTGTPGNLYSMILNSQTRFYILKSASYGNTLWGNSLNDPAQWEFVGMNKNKAVQTVKDRILAGRAKQPVIFHGQLTGNMDVAIPQVPGGRKVIFDGSVNLPEGTLSQDSGTLIFQGHPVIHASISGSAPVSLNQKDWENRQFTMKTLSLKDADFHLSRNASLNSDIKSDNSHITLGSDRAFVDKNDGTGNYVIPEEGTSVPDTVNDRSQYEGNITLNHNSALDIGSRFTGGIDAYDSAVSITSPDVLLTAPGAFAGSSLTVHDGGHLTALNGLFSDGHIQAGKNGKITLSGTPVKDTANQYAPAVYLTDGYDLTGDNAALEITRGAHASGDIHASAASTVTIGSDTPAELASAETAASAFAGSLLEGYNAAFNGAITGGRADVSMHNALWTLGGDSAIHSLTVRNSRISSEGDRTFRTLTVNKLDATGSDFVLRTDLKNADKINVTEKATGSDNSLNVSFMNNPAQGQALNIPLVTAPAGTSAEMFKAGTRVTGFSRVTPTLHVDTSGGNTKWILDGFKAEADKAAAAKADSFMNAGYKNFMTEVNNLNKRMGDLRDTNGDAGAWARIMSGAGSADGGYSDNYTHVQVGFDKKHELDGVDLFTGVTMTYTDSSADSHAFSGKTKSVGGGLYASALFESGAYIDLIGKYIHHDNDYTGNFASLGTKHYNTHSWYAGAETGYRYHLTEDTFIEPQAELVYGAVSGKTFRWKDGDMDLSMKNRDFSPLVGRTGVELGKTFSGKDWSVTARAGTSWQFDLLNNGETVLRDASGEKRIKGEKDSRMLFNVGMNAQIKDNMRFGLEFEKSAFGKYNVDNAVNANFRYMF
What is the function of this protein?
Involved in intestinal colonization, displays in vitro mucinolytic activity, serum resistance, and hemagglutination.  Important to penetrate the intestinal mucus layer.
What are the official names of this protein?
Serine protease pic autotransporter, ShMu.
What are the subcellular locations of this protein?
[Serine protease pic autotransporter]: Periplasm. SUBCELLULAR LOCATION: [Serine protease pic]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Serine protease pic translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: UREF_SACD2
Sequence: MFNNNSLQKLMYLVSPALPVGAYAYSQGLEFAVDGGWLKTEADVSAWIAGVMENSLAELDMPVLVRIYKAWQQGDIEQVKYWNHFLRAGRETHELLLEDDQLGIALKRLLISLEIPHAAEVEKPAFATLFALAGVHWQVPIEQLLQGFAWTWLENQVAAATKLVPFGQTQAQKVILALQPNIAPACEKAFILKDDELGAGLPALAIASAKHERQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSTA_YEREN
Sequence: MKKIVFVLVLMLSSFGAFGQETVSGQFSDALSTPITAEVYKQACDPPLPPAEVSSDWDCCDVCCNPACAGC
What is the function of this protein?
Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells.
What are the official names of this protein?
Heat-stable enterotoxin A, YST-A.
What is the protein family that this protein belongs to?
Belongs to the heat-stable enterotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEP4_PSEPU
Sequence: MTLWTFLAMEPAYFITLATVLGLLVGSFLNVVVYRLPIMLERQWQREAHEVLGLPVTEHERFDLCLPASQCTQCGHRIRAWENLPVLSYLALRGRCSACKQRISVRYPLVEVGCALLSMVVAWRYGASVEALVLLPLTWSLLALSLIDHDQQLLPDAIVLPGLWLGLIVNYFGVWVPLPDAVCGAVVGYLSLWTVYWLFKLVTGKEGMGYGDFKLLALLGAWGGWQVLPLTLLLSSVLGALVGVYLLRVRNDSMGTAMPFGPYLAIAGWIAVLWGDEIYASNMQLLGF
What is the function of this protein?
Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.
What are the official names of this protein?
Prepilin leader peptidase/N-methyltransferase, Protein PilD, Protein secretion protein XCPA.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL7_ALKEH
Sequence: MAVSKEEILETISNMTVMEVVELIEEMEEKFGVTAAAAVAAAPAAAGGEAEAAEEQTEFDVVLSSFGSNKVAVIKAVRGITGLGLKEAKEVVEGAPSPIKEGASKEEAEEIKAKLEEAGASVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: METN1_STAES
Sequence: MIKLNQIVKRYHTKDKDVLAVDHVDLNIESGSIFGVIGFSGAGKSTLIRMFNNLESPTSGEIIIDGDNISQLSKSQLRKKRQKVSMIFQHFNLLWSRNVLKNVTFPLEIAGVPSGLAKQKALELIELVGLKGRESAYPSELSGGQKQRVGIARALANDPDVLLCDEATSALDPQTTDEILDLLLKVREQQNLTIVLITHEMHVIRRMCDEVAVMENGKVIEQGAVSKVFENPQHEVTKRFVKDDLNDDFEDSLEYLEPLDHDAYIVRLNFTGENTTEPIISYMTKTHNIDVNILEADIKNTKNGSLGFLVIHIPHISEEHFKQFKHNLHEQHVNVEVLKHG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EV168_ASFP4
Sequence: MFYPVVQILIGIILVIILILGFYHLKRKPPKKKCKTDTDCKDKGHHCVRGACTDKSCLEAVKQDIKDIKLDPTIRSCDYAPGFYRFNATTADLQSPFGKTRIDLGKVWTTWSKEDEYCQSLCLQHKGSIGWEFDEMSLRGEGNCYCYTNSHPALKNSNNTTVMGIARNVL
What are the official names of this protein?
Envelope protein 168.
What is the protein family that this protein belongs to?
Belongs to the asfivirus envelope protein p22 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: PILR1_LINPE
Sequence: MKPCSVLVVGGTGYIGKRIVSASLYLGHDTYVLKRPGTGLDIEKLQLLLSFKKRGAHLVEASFSDHDSLVRAVRLVDVVICTMSGVHFRSHNILLQLKLVEAIKEAGNVKRFIPSEFGMDPARMGQAMEPGRETFDQKMVVRKAIEEANIPHTYISANCFAGYFVGNLSQLGTLTPPSDKVIIYGDGNVKVVYVDEDDVAKYTIKAIEDDRTVNKTVYLRPPENMMSQRELVAVWEKLSGNQLEKIELPPQDFLALMEGTTVAEQAGIGHFYHIFYEGCLTNFEINAENGEEEASRLYPEVEYTRVHDYLKIYL
What is the function of this protein?
Reductase involved in the lignan justicidin B biosynthesis.  Catalyzes the enantioselective conversion of (+)-pinoresinol into (+)-lariciresinol and of (-)-lariciresinol into (+)-secoisolariciresinol.  Low activity with the other enantiomers.  Abstracts the 4R-hydride from the NADPH cofactor during catalysis.
What are the official names of this protein?
Bifunctional pinoresinol-lariciresinol reductase, PLR-Lp1, (+)-pinoresinol reductase, (-)-lariciresinol reductase.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: CATK_CHICK
Sequence: MLRLHWLALLVLLLPMAAAQLRPEPELDAQWDLWKRTIQKAVQRQGGRNVPEVDLGEEPEVHRCPQRGARLGKHSFQLAMNYLGDMTSEEVVRTMTGLRVPRSRPRPNGTLYVPDWSSRAPAAVDWRRKGYVTPVKDQGQCGSCWAFSSVGALEGQLKRRTGKLLSLSPQNLVYCVSNNNGCGGGYMTNAFEYVRLNRGIDSEDAYPYIGQDESCMYSPTGKAAKCRGYREIPEDNEKALKRAVARIGPVSVGIDASLPSFQFYSRGVYYDTGCNPENINHAVLAVGYGAQKGTKHWIIKNSWGTEWGNKGYVLLARNMKQTCGIANLASFPKM
What is the function of this protein?
Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling.  Displays potent endoprotease activity against fibrinogen at acid pH.  May play an important role in extracellular matrix degradation (By similarity).
What are the official names of this protein?
Cathepsin K, JTAP-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: DEND_HUMAN
Sequence: MLDGPLFSEGPDSPRELQDEESGSCLWVQKSKLLVIEVKTISCHYSRRAPSRQPMDFQASHWARGFQNRTCGPRPGSPQPPPRRPWASRVLQEATNWRAGPLAEVRAREQEKRKAASQEREAKETERKRRKAGGARRSPPGRPRPEPRNAPRVAQLAGLPAPLRPERLAPVGRAPRPSAQPQSDPGSAWAGPWGGRRPGPPSYEAHLLLRGSAGTAPRRRWDRPPPYVAPPSYEGPHRTLGTKRGPGNSQVPTSSAPAATPARTDGGRTKKRLDPRIYRDVLGAWGLRQGQGLLGGSPGCGAARARPEPGKGVVEKSLGLAAADLNSGSDSHPQAKATGSAGTEIAPAGSATAAPCAPHPAPRSRHHLKGSREGKEGEQIWFPKCWIPSPKKQPPRHSQTLPRPWAPGGTGWRESLGLGEGAGPETLEGWKATRRAHTLPRSSQGLSRGEGVFVIDATCVVIRSQYVPTPRTQQVQLLPSGVTRVVGDSPSQSKPGKEEGEGATVFPSPCQKRLSSSRLLHQPGGGRGGEAEGGRPGDSTLEERTFRILGLPAPEVNLRDAPTQPGSPEHQALGPAASGAQGRAEGSEVAVVQRRAGRGWARTPGPYAGALREAVSRIRRHTAPDSDTDEAEELSVHSGSSDGSDTEAPGASWRNERTLPEVGNSSPEEDGKTAELSDSVGEILDVISQTEEVLFGVRDIRGTQQGNRKRQ
What is the function of this protein?
Promotes apoptosis of kidney glomerular podocytes.  Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein (By similarity).
What are the official names of this protein?
Dendrin.
What are the subcellular locations of this protein?
Cell projection, dendritic spine membrane; Peripheral membrane protein. Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Perikaryon. Nucleus. Note=Enriched at the cytoplasmic insertion of the slit diaphragm into the foot process of podocytes and associated with polyribosomes in dendrites.
Protein: FST_HORSE
Sequence: MVRPRHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCDNVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGKCKKTCRDVNCPGSSTCVVDQTNNAYCVTCNRICPEPTSSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSEEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
What is the function of this protein?
Binds directly to activin and functions as an activin antagonist.  Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
What are the official names of this protein?
Follistatin, FS, Activin-binding protein.
What are the subcellular locations of this protein?
Secreted.
Protein: MK06_MOUSE
Sequence: MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILDSIPVVHEEDRQELLSVIPVYIRNDMTEPHRPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPIHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSSPYLDNLVWRESEVNHYYEPKLIIDLSNWKEQSKEKSDKRGKSKCERNGLVKAQIALEEASQQLAERERGQGFDFDSFIAGTIQLSAQHQSADVVDKLNDLNSSVSQLELKSLISKSVSREKQEKGRANLAQLGALYQSSWDSQFVSGGEECFLISQFCCEVRKDEHAEKENTYTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSGGGEFLLSKQLESIGTPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHKTYSSILKHLN
What is the function of this protein?
Atypical MAPK protein.  Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5.  The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6.  May promote entry in the cell cycle.
What are the official names of this protein?
Mitogen-activated protein kinase 6, MAP kinase 6, MAPK 6, Extracellular signal-regulated kinase 3, ERK-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the cytoplasm following interaction with MAPKAPK5.
Protein: MED9_KLULA
Sequence: MTGDTEKEQEPSSGEQQLNVLKRIHEILTKHSSTQTEFIPLLYHSLKQISKHPNNSSNSLDAATSSIRHRLKTAKTLLQQDPAAIELVSKTPEQWQLHIQEKKIELEKKTKHLQRLRESIQKQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 9, Mediator complex subunit 9.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 9 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ECTD_SPHAL
Sequence: MQDLYPSRQRADAEMRPRLDPVVHSEWTNDAPISARQAAAFDRDGYIVLEDIFSADEVAFLQKAAGNLLADPAALDADTIVTEPQSNEIRSIFEIHAQSPVMARLAADARLADVARFLLGDEVYIHQSRLNYKPGFKGREFYWHSDFETWHVEDGMPRMRALSMSVLLAENTPHNGPLMVIPGSHRTYLTCVGETPDDHYLSSLKKQEYGVPDEESLAELAHRHGIVAPTGKPGTVILFDCNLMHGSNGNITPFPRANAFLVYNAVSNRLEKPFGVEKPRPWFLARRGEPAALRVERGPLVETVPA
What is the function of this protein?
Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte.  Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.
What are the official names of this protein?
Ectoine dioxygenase, Ectoine hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PhyH family. EctD subfamily.
Protein: GLMS_STRCO
Sequence: MCGIVGYVGPQSALDVVMAGLKRLEYRGYDSAGVAVLADGGLATAKRAGKLVNLDKELSEHPLPAAATGIGHTRWATHGGPTDANAHPHLDNAGRVAVVHNGIIENFAPLRAELAERGHELPSETDTEVVAHLLAEEYSACADLAEAMRLVCGRLEGAFTLVAVHADAPDVVVGARRNSPLVVGVGEGEYFLASDVAAFIAHTRDAVELGQDQVVELRRDGVRVTGFDGSPADVRSYHVDWDASAAEKCGYASFMLKEIAEQPKAVADTLLGRIDGSGTLSLDEVRIPPGVLREVDKVVVVACGTAFHAGLIAKYAIEHWTRIPCEVELASEFRYRDPILDQQTLVVAISQSGETMDTLMALRHAREQGARVLAICNTNGSTIPRESDAVLYTHAGPEVAVASTKAFLTQLVACYLVALYLGQVRGTKYGDEIGDVVRDLSGISGAVERVLGTMDPVRQLARSLAHKNTVLFLGRHVGHPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEDLPVVVVVPSPRGRSVLHDKIVSNIQEIRARGARTIVIAEEGDEAVVPYADHLVRIPATPTLLQPLVATVPLQVFACELATARGNEVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXPA4_ORYSI
Sequence: MAIAGVLFLLFLARQASAAGYGGWQSAHATFYGGGDASGTMGGACGYGNLYSQGYGTNTAALSTALFNDGAACGSCYELRCDNAGSSCLPGSITVTATNFCPPNYGLPSDDGGWCNPPRPHFDMAEPAFLHIAQYRAGIVPVSFRRVPCVKKGGVRFTVNGHSYFNLVLVTNVAGAGDVRSVSIKGSRTGWQPMSRNWGQNWQSNAFLDGQSLSFQVTASDGRTVTSNNVAHPGWQFGQTFEGGQF
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  Required for normal plant growth.  May be required for rapid internodal elongation in deepwater rice during submergence.
What are the official names of this protein?
Expansin-A4, Alpha-expansin-4, OsEXP4, OsEXPA4, OsaEXPa1.22.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: SYC_ACIBY
Sequence: MQPFVLYNSEQRKKVEFVPRKEGHIDMYVCGMTVYDYCHIGHARVMVAFDYIIRFLRSQGWKVRYIRNITDIDDKIIKRANENGETIQQLTTRFIDAMNEDAANLGCLAPDEAPKATEYIDQMQNMIGNLVNKGAAYPASNGDVYFEVTKFEKYGRLSGRKLDDMQAGASERIDVEVEKKHPFDFVLWKHAKENEPSWASPWGNGRPGWHIECSAMSTCCLGNHFDIHGGGSDLMFPHHENEIAQSEASTGEQYVNYWMHVGFINVDGEKMSKSLGNFFTIRDVMEKFHPEVIRYFIVSSHYRSPVNFSDVALKEAKTSLTRFYHSFKAYQQVYGQTTTEALDQSFIERFNNAMCDDFNTAEAMAVLFELNKELNRAVKEEQADQATVLYSTLRHLTNILGLVQHNVDDFLKSDIGQDALALSDAEIEDFIQQRVDAKKAKDFAKADSIRQSLLEQGVVLEDTRQGTVWRRAD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_RALPJ
Sequence: MQWEVVIGLETHTQLSTVSKIFSGASTAFGAAPNTQAAPVDLALPGVLPVLNKGAVERAIVFGLAIGAKIAPKSIFARKNYFYPDLPKGYQISQYEIPVVQGGTLTFQVEGKNGQPGYEKTVQLTRAHLEEDAGKSLHEDFAGMTGIDLNRAGTPLLEIVTEPDMRSAAEAVAYAKALHALVMWLGICDGNMQEGSFRCDANVSVRRGPDAPFGTRCEIKNLNSFRFLEEAINYEVRRQIELIEDGGTVVQETRLYDPDRKETRSMRSKEDAQDYRYFPDPDLLPLVIGDDWIERVRATLPELPAAMAARFESAYGLPKYDASILTATKATAAYFEAVVADAGAANAKAAANWIMGEVASNLNRADLDIDAAPVSPAQLAKLLARIADGTISNNTAKKDVFPAMWAGEHGGDADAIIAEKGLKQMSDSGELEKIIDDVLAANAKSVEEFRAGKEKAFNALVGQAMKATRGKANPAQVNDLLKKKLGAA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: CCDB1_HUMAN
Sequence: MASATAPAAAVPTLASPLEQLRHLAEELRLLLPRVRVGEAQETTEEFNREMFWRRLNEAAVTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRGATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLTKNVDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQELIIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMCHLTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL
What is the function of this protein?
May negatively regulate cell cycle progression.  May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
What are the official names of this protein?
Cyclin-D1-binding protein 1, Grap2 and cyclin-D-interacting protein, Human homolog of Maid.
What is the protein family that this protein belongs to?
Belongs to the CCNDBP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EIF3D_HUMAN
Sequence: MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDESSFQLVDTARTQKTAYQRNRMRFAQRNLRRDKDRRNMLQFNLQILPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQKPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGKERYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYSLPDGTFSSDEDEEEEEEEEEEEEEEET
What is the function of this protein?
(Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d, Eukaryotic translation initiation factor 3 subunit 7, eIF-3-zeta, eIF3 p66.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.