PharMolix/UniProtQA huggingface dataset:
Protein: EZA1_ARATH
Sequence: MVTDDSNSSGRIKSHVDDDDDGEEEEDRLEGLENRLSELKRKIQGERVRSIKEKFEANRKKVDAHVSPFSSAASSRATAEDNGNSNMLSSRMRMPLCKLNGFSHGVGDRDYVPTKDVISASVKLPIAERIPPYTTWIFLDRNQRMAEDQSVVGRRQIYYEQHGGETLICSDSEEEPEPEEEKREFSEGEDSIIWLIGQEYGMGEEVQDALCQLLSVDASDILERYNELKLKDKQNTEEFSNSGFKLGISLEKGLGAALDSFDNLFCRRCLVFDCRLHGCSQPLISASEKQPYWSDYEGDRKPCSKHCYLQLKAVREVPETCSNFASKAEEKASEEECSKAVSSDVPHAAASGVSLQVEKTDIGIKNVDSSSGVEQEHGIRGKREVPILKDSNDLPNLSNKKQKTAASDTKMSFVNSVPSLDQALDSTKGDQGGTTDNKVNRDSEADAKEVGEPIPDNSVHDGGSSICQPHHGSGNGAIIIAEMSETSRPSTEWNPIEKDLYLKGVEIFGRNSCLIARNLLSGLKTCLDVSNYMRENEVSVFRRSSTPNLLLDDGRTDPGNDNDEVPPRTRLFRRKGKTRKLKYSTKSAGHPSVWKRIAGGKNQSCKQYTPCGCLSMCGKDCPCLTNETCCEKYCGCSKSCKNRFRGCHCAKSQCRSRQCPCFAAGRECDPDVCRNCWVSCGDGSLGEAPRRGEGQCGNMRLLLRQQQRILLGKSDVAGWGAFLKNSVSKNEYLGEYTGELISHHEADKRGKIYDRANSSFLFDLNDQYVLDAQRKGDKLKFANHSAKPNCYAKVMFVAGDHRVGIFANERIEASEELFYDYRYGPDQAPVWARKPEGSKKDDSAITHRRARKHQSH
What is the function of this protein?
Polycomb group (PcG) protein.  Catalytic subunit of some PcG multiprotein complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target genes, mainly abscisic acid (ABA) responsive elements (PubMed:30307069).  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development (By similarity).  Forms a nuclear complex with CLF and HXK1 to target common glucose-responsive genes and regulate glucose signaling by glucose-mediated gene repression (PubMed:35394700).  Affects the recruitment of HXK1 to the target chromatin (PubMed:35394700).
What are the official names of this protein?
Histone-lysine N-methyltransferase EZA1, CURLY LEAF-like 1, Protein SET DOMAIN GROUP 10, Protein SWINGER.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. EZ subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCD_XANAC
Sequence: MSIKSDRWIKRMAEQHAMIEPFEPGQIKHDAAGQRIVSFGTSSYGYDVRCSREFKVFTNINSTIVDPKHFDPGSFVDIESDVCIIPPNSFALARTVEYFRIPRDTLVVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPARIYANEGVAQMLFFQSDEVCETSYKDRGGKYQGQTGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: SYY_STRPJ
Sequence: MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQGQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIETGISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVITVPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDEIEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKELKQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYVLSDADKLENELTVIRRGKKKYFVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQHA_ECOLC
Sequence: MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPNIFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL22_KORVE
Sequence: MEFTAKANFVRVSPQKARLVLDLIKGQRVEDALNTLLFTKKGIAPAIYKLVHSAMDNANYLSNEKGLDLDLDRLYVKKAIANDGPRMKRIRPAPMGRAFRYQRRISHIEISLAEKPGFQGSTATTVEDEAPKAKGAKGAKAKKAPAKKAAAKKAPAKKFAGKKTAKR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SCO21_RICPR
Sequence: MRNNKNQMYIIKIFIAIAMITGIIFLYLFYSSLTTSKLKETSNMDDSLKIKFTLIEQQGKKFDSTNLQGYLSLIYFGTTYSLYDNQALKRVEDIIKILKRENILLQVVFITLDPEHDTSEVLKKYLEKIDSNFIGLTGRVQDIEQLAQQFKVFYTSKIFDVKTNEYALQHSNFVYLISSDGKILSHYYLGS
What are the official names of this protein?
SCO2-like protein RP031.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
Protein: TCAA_STAA3
Sequence: MKSCPKCGQQAQDDVQICTQCGHKFDSRQALYRKSTDEDIQTNNIKMRKMVPWAIGFFILILIIILFFLLRNFNSPEAQTKILVNAIENNDKQKVATLLSTKDNKVDSEEAKVYINYIKDEVGLKQFVSDLKNTVHKLNKSKTSVASYIQTRSGQNILRVSKNGTRYIFFDNMSFTAPTKQPIVKPKEKTKYEFKSGGKKKMVIAEANKVTPIGNFIPGTYRIPAMKSTENGDFAGHLKFDFRQSNSETVDVTEDFEEANISVTLKGDTKLNDSSKKVTINDHEMAFSSSKTYGPYPQNKDITISASGKAKDKTFTTQTKTIKASDLKYNTEITLNFDSEDIEDYVEKKEKEENSLKNKLIEFFAGYSLANNAAFNQSDFDFVSSYIKKGSSFYDDVKKRVSKGSLMMISSPQIIDAEKHGDKITATVRLINENGKQVDKEYELEQGSQDRLQLIKTSEK
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FENR_ACISJ
Sequence: MHPSPSSPTPQAADAVVIGAGPVGLFQVFQLGLQGIAAHLVDALPHVGGQCAELYPDKPIYDIPGIPVCTGLGLVELLQRQIAPFAPTLHLGQQIHALAAQADGRILLTTTAGTALLARSVFIAAGVGAFVPRAIKAEGVEALAPGQLLYHPDAATATRAATGKRVVVHGGDEAAVQAALDCVDAAAQVLLLHRRDAFQAAPAPLAQLQALREAGRIQVVIGQITGVETAPDGTLQALALLDPQGQPQRQPLDLLLAYLGISPRLGPIADWGLAMDRKQLAVDTATFATSVPGIYAVGDINTYPGKRKLILCGFHEATLAAFAEAERQAGHKLPLEYTTSSERLQARLGVAPAR
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: MURG_PSELT
Sequence: MRISAAGGGTGGHLYPAVSILEKLAEMKKLNVTYFCLEKGIESKILPLEHPEYKLIKIDLKGLERPIWKPSNFTRLLKISQSESIIALEIKQCDFGLMTGGYISYPVGKVCKKLKKPFFIQEQNVVPGLANKALSLSAKKIFVAFDKTVEFFPKSVRNKILVTGNPVREKDNEEMLFGKDYVLVLGGSRGSEFINNLMEEVYKVEHNLKFVHSTGSKEWVDRLSIFENVKAVDYIYNASAAWKGARAVIARAGATTIGEMLYYGLPGILVPWDGATGSHQLYNALEIEKMGKALVLKECDATVSTLLKKLYQVLEMDKKPKMKINPAEIIAKTILEELK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UREG_ECOLX
Sequence: MQEYNQPLRIGVGGPVGSGKTALLEVLCKAMRDTYQIAVVTNDIYTQEDAKILTRAEALDADRIIGVETGGCPHTAIREDASMNLAAVEELAIRHKNLDIVFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITHSDLLVINKIDLAPYVGASLEVMEADTARMRPVKPYVFTNLKKKVGLETIIEFIIDKGMLGR
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_STRPG
Sequence: MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADASNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y886_STAAW
Sequence: MRLYINEIKIKDDILYCYTEDSIKGLSEVGQMLVDSDNYAFAYTLDDGKAYAYLIFVQETWTMLHENMTKKIIINDELELTEFHQELTYILDNIKGNNNYGKEFVATVEETFDIE
What are the official names of this protein?
UPF0738 protein MW0886.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.
Protein: HEM3_SHEFN
Sequence: MSENIIRIATRKSPLAMWQAEFVKAELERIHPGLTVELLPMSTKGDVILDTPLAKIGGKGLFVKELEVAMLENRADIAVHSMKDLPVEFPEGLGLQVICEREDPRDAFVSNNYKSISELPQGAVVGTSSLRRQCQIRAARPDLVIKDLRGNVGTRLAKLDSGDYDAIILAAAGLIRLKLNERIANFISAEESLPANGQGAVGIECRTDDARVKALLAPLEHLETRYRVLAERAMNTRLEGGCQVPIGAFAEINGDNLTLRGLVGNPDGSQIIIGTVSGSKTDAVALGESLAEDLLSRGAKTILDAVYAS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: TUSB_YERPG
Sequence: MLYTVSHSPYHCDLSALLRLATSEDDILLLQDGVIAALKESETLKLLLNNPASLFVLEDDVIARGLVGQISDNATLISYTHFVDLTLRHQQQLAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFC5_CAEEL
Sequence: MGSRTGSREEHSLQFLNLTKMTTTTASNLPWVEKYRPSKLDELVAHEQIVKTLTKFIENRTLPHLLFYGPPGTGKTTTVLAAARQMYSPTKMASMVLELNASDERGIDVVRNTIVNFAQTKGLQAFSTSSNTGTVPFKLVILDEADAMTKDAQNALRRVIEKYTDNVRFCIICNYLASIVPAIQSRCTRFRFAPLDQKLIVPRLEYIVETEQLKMTPDGKDALLIVSKGDMRTVINTLQSTAMSFDTVSENTVYQCIGQPTPKEMKEVVKTLLNDPSKKCMNTIQTKLFENGYALQDVITHLHDFVFTLDIPDEAMSAIITGLGEVEENLSTGCSNETQLAAVVAAFFEAKRLCVKEMKNLEIEDMEF
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.
What are the official names of this protein?
Probable replication factor C subunit 5, Activator 1 subunit 5.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPC_THEKO
Sequence: MVFGLSRAIRKAEKNAIIAELKVYSPKYGDLLKGRNPFEILRAYERAGAVGISYITDPKYFRGSFEFLRKLCRETELPVLRKDFIASKEEVERTAEAGASAVLLITRLLKEELPEFVDFAKEHGLDTLVEVHSEEELAIALQTDSTMIGINNRDIGKLELDDGNVSLTEKLAPLIPKRYVKVSESGIAGTEDLKRALRHADAALIGTALMKTPDPEEFLRKLVEVEV
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: TRMD_TROW8
Sequence: MFVMRCDFVSIFPEYFDVLDISLIGKARRNGLLDLRVHNLREYSEAGRVDSSPYGGGPGMVMSAEPWARAIEHIATGESLVVFPSPSGQPYSHDLAQSLSSEMHIVFCCGRYEGIDNRIYEWTATRLRSSGISIGDYVLNGGEIAALVILEGFVRFIPGVLGNPESLVEESYQYNLLEYPVYTKPAVWRGLEVPDILLSGNHDLIREWRYKKQLEITQKTRPDLYSTHIYETDS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_THESQ
Sequence: MIQQETYLNVADNSGAKKLRVIRVIGGFHKKYGTVGDIVVCSVREAIPNSDVKKGDVVRAVIVRTKKEIRRSDGTYIRFDDNAAVLIDKFNAPRGTRIFGPVARELREKGFMKIVSLAPEVW
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TRMI_MYCTU
Sequence: MSATGPFSIGERVQLTDAKGRRYTMSLTPGAEFHTHRGSIAHDAVIGLEQGSVVKSSNGALFLVLRPLLVDYVMSMPRGPQVIYPKDAAQIVHEGDIFPGARVLEAGAGSGALTLSLLRAVGPAGQVISYEQRADHAEHARRNVSGCYGQPPDNWRLVVSDLADSELPDGSVDRAVLDMLAPWEVLDAVSRLLVAGGVLMVYVATVTQLSRIVEALRAKQCWTEPRAWETLQRGWNVVGLAVRPQHSMRGHTAFLVATRRLAPGAVAPAPLGRKREGRDG
What is the function of this protein?
Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase TrmI, tRNA(m1A58)-methyltransferase, tRNA(m1A58)MTase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
Protein: NADK_CALBD
Sequence: MEVGIFVNFQKERSSEILENIVSIFNQNGVNWLLVNEENKKTKNFDLLITIGGDGTLLNVVEKASKEATPVLAINCGRLGYLTEEVGDDIEKAIFNLLKKEYFIEERHIVEAKVKEKVFFALNDVCIVRNTFNIVDLCLYIDGVFAQEYRSDGIIVATATGSTAYSLSAGGPIVEPQLGVILVTPICPHSLSSRSLVLGSARTIKVENSSSENVQVVVDGRFVDELAPEEFVECKISQHNLKLIRLKQRNFYEILREKIKE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_RICTY
Sequence: MYNIFKGLITALITPFKNNKLDLYAFESILNQQIKHEVDAVLIAGSTGEANSLSFEEYKLLLKTSVEIVNNRMPIISGCSSNNTAYAIELAIASKKIGVDGFMASPPSYVKPTQHGIYKHFEALHEACNLPIMLYSAPTRSGVDFSDETILRLSKLPRILALKDCGVDLERPMRIRAIVKEDFNILTGNDEVVLAFHAQGVIGWISVTSNIAPKICKELLDKWYNNDIQGALEMHQKLLPLYKALFLESNPIPVKYAAHYLGLCENEIRLPLTEASDSAKKQIKKIITSLSIKI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGAL4_ARATH
Sequence: MVLNFRDKSCIFLAILCCLSLSCIVKASVSYDRKAVIINGQRRILLSGSIHYPRSTPEMWPGLIQKAKEGGLDVIETYVFWNGHEPSPGQYYFGDRYDLVKFIKLVHQAGLYVNLRIGPYVCAEWNFGGFPVWLKFVPGMAFRTDNEPFKAAMKKFTEKIVWMMKAEKLFQTQGGPIILAQIENEYGPVEWEIGAPGKAYTKWVAQMALGLSTGVPWIMCKQEDAPGPIIDTCNGYYCEDFKPNSINKPKMWTENWTGWYTDFGGAVPYRPVEDIAYSVARFIQKGGSLVNYYMYHGGTNFDRTAGEFMASSYDYDAPLDEYGLPREPKYSHLKALHKAIKLSEPALLSADATVTSLGAKQEAYVFWSKSSCAAFLSNKDENSAARVLFRGFPYDLPPWSVSILPDCKTEVYNTAKVNAPSVHRNMVPTGTKFSWGSFNEATPTANEAGTFARNGLVEQISMTWDKSDYFWYITDITIGSGETFLKTGDSPLLTVMSAGHALHVFVNGQLSGTAYGGLDHPKLTFSQKIKLHAGVNKIALLSVAVGLPNVGTHFEQWNKGVLGPVTLKGVNSGTWDMSKWKWSYKIGVKGEALSLHTNTESSGVRWTQGSFVAKKQPLTWYKSTFATPAGNEPLALDMNTMGKGQVWINGRNIGRHWPAYKAQGSCGRCNYAGTFDAKKCLSNCGEASQRWYHVPRSWLKSQNLIVVFEELGGDPNGISLVKRT
What is the function of this protein?
Preferentially hydrolyzes para-nitrophenyl-beta-D-galactoside.  Can hydrolyze para-nitrophenyl-beta-D-fucoside with 5 time less efficiency.
What are the official names of this protein?
Beta-galactosidase 4, Lactase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: TRMD_MANSM
Sequence: MWIGIISLFPEMFKAITEFGVTGRAVKQNLLQVSCWNPRDFTHDKHKTVDDRPYGGGPGMLMMVQPLRDAIHAAKAEAGDGVKVIYLSPQGRKLDQTGVTELAANEKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFVPGVLGKQASAEEDSFAEGLLDCPHYTRPEVLDGYVVPPVLMSGNHEEIRKWRLKQSLERTWLRRPELLEKLALTDEQKKLLKDIIEAYHIRQSKTSDNG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB2_CORGL
Sequence: MIFLYAALGGFFGGFLRWSLAQLFPGKRATLAANTLACLAGGFFVSLDLPHLYTVLLIAGFCGALSTWSTLAKELGQLLNEKKWWPMLGYLSLTFTLGYSAVFLGMRL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TGB1_WCMVM
Sequence: MDHIHLLLSAHGFTRTRLAKSKPIVVHAIAGSGKSTVIRKILSDLPTPKAYTLGKPDPYSLSNPTIKAFAQFKRGTLDILDEYGQLPLTDLDSSFEFIFTDPYQAPTDNLFEPHYTLETTYRFGPNTCNLLNQAFQSNITSLVTKDNISFGSPYLVDPVGTILAFQPDTYLILCLHQASFFKVSDVIGYQWPTVTLYLACKISEIPEEERHLLFIGLTRHTESLLILGPDAFDSSP
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Increases plasmodesma size exclusion limit.  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity).
What are the official names of this protein?
Movement and silencing protein TGBp1, 25 kDa protein, Silencing suppressor P25, Triple gene block 1 protein, TGBp1.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp1 protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: Y2114_ARCFU
Sequence: MRKLTLLPLLLIITGLLTVQAAELHFQVFIKGYNGTAELGIFGENLSKVETVKNGSIISLPAGNYTLTLFALNKTFVKDLRLDSNKTVTFNLLFTNRTENLSMMRHAIVQPSLEVFEIVLITNSGGENFEGDLAIPLPEHTGLKISDSSLSFLDFSDLNGNLTLKKLIVPANSTGEVSITYRLVKPKLSLSGAENQTVLIFTTLPVTNQSNAAYRGVQQFKGVDYSVYQCKTKCVLEFKVEPEIKIDKTSAFVILTASALIFIYLFTKRGGWEK
What are the official names of this protein?
Uncharacterized protein AF_2114.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RHNO1_RAT
Sequence: MPPRKRRRQCQKAQLLFHQQPLEGPKPHYESHQQPITHTVQVPSKPIDQSTITSWVLPQFDTAAESRFPTHRKHHRDQARHPTRRSTCKFPRLTFESPESSSSETLLLSNREQLQNSEKDAPRRPLVPLFSPQSCGELSVHVPQSLPHVFMPPDIQTPGSSVREDPISPDQKENSLPSCILGPRTPRTPEPGPVLVKDTPEEKYGIKVTWRRRRHLFAYLKERGKLDKSQFLVKT
What is the function of this protein?
Plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation (IR) during the S phase.  Recruited to sites of DNA damage through interaction with the 9-1-1 cell-cycle checkpoint response complex and TOPBP1 in a ATR-dependent manner.  Required for the progression of the G1 to S phase transition.  Plays a role in the stimulation of CHEK1 phosphorylation (By similarity).
What are the official names of this protein?
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to sites of DNA damage in a H2AX-independent manner.
Protein: RL24_STRZT
Sequence: MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKHQRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ZN467_RAT
Sequence: MRETLEALNSLGFSVGQPEMAPQSEPRDGFSNPQEKMSSRDESTLHSCSGPETPGQKEGIHTEQAEAPCMGSQACIPQKAEPASSVPGEEWMIRKVKVEDEDQEAEEEVEWPQHLSFLPSPFPTPDLGQLAVAYKLEPGTPGTLGGIALSGWAPIPEKPYGCEECERRFRDQLTLRLHQRLHRGEGPCACPDCGRSFTQRAHMLLHQRSHRGERPFPCSECDKRFSKKAHLTRHLRTHTGERPYPCAECGKRFSQKIHLGSHQKTHTGERPFPCTECEKRFRKKTHLIRHQRIHTGERPYQCTQCTRSFTHKQHLVRHQRVHDAASRTRSSPDIPATPHPPTASLAPSPTGPKPFACSHCGQSFGWKKNLATHQSLHLTEGRPFGCDECALGTNVDPAAEPSACTPHAPDCGPGSGPVAPQRTTSSERSFFCPDCGRGFAHGQHLARHRRVHTGERPFACAQCGRRFGSRPNLVAHSRAHSGARPFACAQCGRRFSRKSHLGRHQAVHTGSRPHACAVCARCFSSKTNLVRHQAIHTGSRPFSCPQCAKSFSRKTHLVRHQRIHGEAALPASASNLSAPAWSNPSEVVPPPIFF
What is the function of this protein?
Transcription factor that promotes adipocyte differentiation and suppresses osteoblast differentiation in the bone marrow.  Enhances the osteoclast-supporting ability of stromal cells.  Binds with STAT3 the consensus sequence 5'-CTTCTGGGAAGA-3' of the acute phase response element (APRE).  Transactivates several promoters including FOS, OSM and PPARG.  Recruits a histone deacetylase complex (By similarity).
What are the official names of this protein?
Zinc finger protein 467.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MATK_TRIWO
Sequence: MKEYRVYLERARSRQQDFLYPLIFREYIYGLAYSHNFNRSIFVENGGYDNKYTLLNVKRLITRMYQQNHLIISANDSNKNPFLGYNKNFYSQIISEGFAIVVEIPFFLQLSSSLEEAEIIKSYKNVRSIHSVFPFLEDKFTYLNYVSDIRIPYPIHLEILVQILRYWVKDVPFFHLLRLFLYHFCNWNCFIPTKKSISTFSKSNPRLFLFLYNFYVCEYESIFLFLRNKSYHLRLKSFSVFFERNFFYAKREHLVEVFSKDFSYTLPFFKDPNIHYVRYQGKCILASKNVPFLMNKWKYYFIHLWQCFFDVWSQPRTININQLSEHSFQLLGYFSNVRLNRSVVRSQMLQNTFLIEIVSKKLDIIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIERFLRICRNLSHYYNGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEELLEEFFTEEEEILSLIFPRDSFTLHRFHRNRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: QUEG_STAA8
Sequence: MGGIRLDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPLIRATAYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE
What is the function of this protein?
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
What are the official names of this protein?
Epoxyqueuosine reductase, Queuosine biosynthesis protein QueG.
What is the protein family that this protein belongs to?
Belongs to the QueG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBBB5_HYAOR
Sequence: GRRPCCNECGICDRSLDPMCICEDLVPQCHEGCQACEEVDTGTPMYQCRSFEYYHCGTPCL
What is the function of this protein?
Serine protease inhibitor (PubMed:33666645).  Inhibits trypsin (Ki = 41 nM) and weakly inhibits chymotrypsin (Ki = 410 nM) (PubMed:33666645).  Does not inhibit bacterial subtilisin (PubMed:33666645).
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor B5, HOSPI-B5.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.