PharMolix/UniProtQA huggingface dataset:
Protein: Y984_HAEIN
Sequence: MLAIISPAKTLDFESAVKNFPVSQPHFTDYSEQLIEVCRKLSPQDLSSLMSISDKLAGLNAARFAEWTKIHNENNSRPALFAFKGDVYTGLDADSLSEDDVIFAQSHLRMLSGLYGLLKPLDLMQPYRLEMGTKLANPKGKDLYAFWGNVITQAVQQAIDEQGDNVLVNLASDEYYKSVKESQINAKIIKPVFLDNKNGKYKVISFYAKKARGLMCRYIIQHHLTEIEQLKEFDLGGYWFDSASSTETEFVFKRDINE
What are the official names of this protein?
UPF0246 protein HI_0984.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: CLPP_BORGP
Sequence: MHNLIPTVIEHTGNYERVFDIYSRLLRERIIFLSGEINDLKADTVIAQLLFLESEDSNKDIYLYLNSPGGSITAGLAIYDTMQYIKPDVRTICIGQAASMGAFLLAGGAKGKRESLAYSRIMIHQPWGGISGQASDINIQANEILRLKKLIIDIMSNQIGIDKEKLALDMERDYFMTSNDALKYGLIDSILVRE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNB_YERPG
Sequence: MFQDNPLLAQLKQQLHTQTPRVEGVVKGTEKGFGFLEVDGQKSYFIPPPQMKKVMHGDRIIATLHTDKDREIAEPETLVEPFLSRFVGRVQRKDDRLSIVPDHPLLRDAIQCRPVRELTHSFQNGDWAVAEMCRHPLKGDRAFQADLTAFITNGEDHFVPWWVTLARHNLEREAPAMVESALNDAELEREDLTALNFVTIDSASTEDMDDALFVQDNGDGSWLLTIAIADPTAYVVENSELDLTARKRAFTNYLPGFNIPMLPRDLSDNLCSLRPNERRPVLVCRVTITEEGTLSNDIRFSAAWVESKAKLVYDDVSDWLEGNNRWQPQDTAIAEQITLLKRICDARSNWRQQHALVFKDRPDYRFLLGEKGEVLDIIVEHRRIANRIVEECMIAANVCAALALREHLGFGIYNVHTGFDPALVEQAASVLKANGVGADPQALLTLPGFCELRRHLDALPTQFLDSRIRRFQTFAEISTVPGPHFGLGLEAYATWTSPIRKYGDMVNHRLLKAMITGQQAEKPQEEITVQLAERRRLNRMAERDVGDWLYARYLQPQAGTDTRFTAEIIDITRGGLRVRLLDNGAVAFIPAPFIHAVRDEVVCSQETGTVQIKGETVYSQSDKIEVRIAEVRMETRNVIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELD_CAMJE
Sequence: MQYKNQNLTHFVKAAGUAAKLSPGGLKTILNFMQKTPALLSDIGNNEDASVYQISPDLALVQTLDFITPIVDSAYHFGAIAAANALSDVFAMGAEVINALNIVGFDTCNHDLNILKELLEGANDKVKECNALVVGGHTIESTELFFGLSVTGKVHPSKFIANNTSKIGDCIILTKPLGTGILSTALKAQMLNQKHLDIMLKNMIELNYKASQIALKFHPSAMSDVTGFGLLGHLKEMLNKNISFEIFESELPFLDGVKEYFNMGLIPAGAYKNLEFIKELTPDLNEEKLLLCDPQTSGGLLISISEKDSLECLKKLEDENIQAKIIAKVVNKQENDIIIS
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: IF3_BARBK
Sequence: MTPNQKDGPRSNQEIRVPCIQLINDEGQNQGIVSTQEALAMAANIGLDLVEIVPNAEPPVCKIVDLGKLKYQNQKKAAETRKKQKIIEIKEIKLRPNVDVHDYGVKLKAIHRFIEHGNKVKITLRFRGREMAHQDLGVKLLERMKEDVSEIAKIESEPKLENRQMMMVIAPKS
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFEB_YERPE
Sequence: MRDKTGPKFGPYQPDDEAVSPSRRRLILGMGMVSGALVLGGAKTAQAADCRSPDVAGTQDERWQKQPFYGQHQAGVLTPQQAAMMLVAFDVLATDKTSLIRLFKLLTERLAFLTTGGRAPSVNAKLPPLDSGIMGPEIYPDNLTVTVSVGNALFDERFGLQGQKPLRLQRMTRFPNDSLDAGLCHGDVMLQICANTNETVIHALRDIIKHTPDLLSVRWKREGFISAHAARSKGQDTPINLLGFKDGTANPKISNKPLINNVVWVSNNAGEPAWAVGGSYQVVRIIRFKVEFWDRTPLQEQQTIFGRDKNSGAPLGMQHEHDEPNYAKDPEGKVIPMDAHIRLANPRTIETQRNLMLRRGYSYSLGVSNSGQLDMGLLFVCYQSDLAQAFLTVQERLNGEALEEYVKPIGGGYFFTLPGVADANHYLAQSLLEA
What is the function of this protein?
Involved in the recovery of exogenous heme iron.  Extracts iron from heme while preserving the protoporphyrin ring intact.
What are the official names of this protein?
Deferrochelatase, Peroxidase EfeB.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family. EfeB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: MERB_BACCE
Sequence: MKTEIQEIVTRLDQQSNKGEGGESMKWLFRPLLQMLAGGESVTIEDMATTTGKPVEEVKKVLQSLPSVEIDEQGRVVGLGLTLIPTPHHFTVDGKQLYAWCALDTLIFPALIGRSVNIESPCHSTGEPIRLNVEPDHIVSVEPSTAVVSIVTPDDMSSIRTAFCNEVHFFSSPNAAEDWLDQHPGGKVLSVEDAFELGRLMGTRYEESRPANGSCCDI
What is the function of this protein?
Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate.  One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.
What are the official names of this protein?
Alkylmercury lyase, Organomercurial lyase.
What is the protein family that this protein belongs to?
Belongs to the MerB family.
Protein: GSA_CORA7
Sequence: MWAMPNSSQLNQQNTSQSAEWFERATKVTPGGVNSPVRAFGSVGGQARVIARGEGSRLWDIDGNEYVDLVSSYGPMIHGNAHPAIVEAVQKAAADGLSFGAPTEGETLLAEHIVKRTAVEQVRLVNSGTEATMSAVRLARGFTGRAKVLKFEGCYHGHVDALLASAGSGVATFALPDSPGVTGASAADTIVVPYNDLDAVREAFAAHPGEIACIIAEAAAGNMGTVAPEEGFNAALKEIAHADGALLILDEVMTGFRTSYKGWFGVDGVAGDLVTFGKVVSGGLPAAAFGGRADVMASLAPSGPVYQAGTLSGNPVAMASGLASLELANAELYPRLQDNADRLTGLITEALSAAGVEHYIQRAETMFSIRFAEGQGRNFADMQAADTWRFAPFFHALLEGGVYVPPSAFETWFVSDALTDNDFEVIEAALKPAAQAAASAQRPQ
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_PARUW
Sequence: MPDLISTEELTRLEHMIVYEKRAFSQGYQLIAGIDEAGRGPLAGPVVAAACILPKGLLVPQINDSKKLSPKVRERLFERLTTDSAVRYGIGIIGQAEIDRVNIYQATILAMLMAIQQLPVTPDYVLVDGMNLPHPDLPCLKIIKGDQLSQSIAAASIIAKETRDRLMCQYHREWPGYGFNQHKGYATELHLEALFKQGPCPIHRRSFDPIKSMLEVEIADDF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_FRATH
Sequence: MSNISAKLVKELRERTGAGMMECKKALVAAAGDIEKAAEEMRISGQAKADKKASRVAAEGVIEVYAADGRAILLEINSETDFVARDETFKKFAQEAVKAAHAANAKTIEEVLAAKTSNGETVEEARKSLIAKIGENIQVRRVKTVEAETLGAYIHGSKIGVVAALEGGDEDLAKDVAMHVAAANPMVVSGDQVPADVVAKEKEIFTAQAKESGKPAEIIEKMIVGRIRKFLDEVALLGQDFVKDPAIKVEKLVKDKGAKVVNFIRLDVGEGIEKKEEDFAAEVMSQIKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC2_LACPL
Sequence: MKKYRKILAMLAVLAIVLVLSGCSNTPITDKSTGFWDGLIILNFSRAIIWLSNLFGHSYGLGIIVFTLIIRIIILPLMIFQTRNMVAMQEVQPQMKALQKKYSSRDMETQQKLQAEMKKLYAKHGVHPMASMLPLLVQLPILIALYQAIWRTQALKTGSFLWLQLGSKDPYYVLPILAAIFTFASSWLAMKSQPEQNGMTTSMTYLMPVIILITAINVPSALSLYWVISNAFQVGQTLLLQNPFKINREREAKKQAERDRKRTLEKARKRAIRNHKR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 2, Foldase YidC 2, Membrane integrase YidC 2, Membrane protein YidC 2.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRFE_XENTR
Sequence: MDLSLHVALCLGMLALCLAMPPKEKQVRWCAKSKSEFSKCRDLVNTCKNKEITLSCVEKSSTDECLTAIQNDRADAICVDGGDVYKGSLQPYNLKPIMAENYGSHTEPDTCYYAVAVVKKSSTFTFDELRDKRSCHTGIGKTAGWNVIIGLLLEKQLLKWEGPDTESLEKAVSKFFKASCVPGAKEPKLCQQCAGKKEHKCARSNNEPYYNYAGAFKCLQDDKGDVAFVKHSTVPEELHKDYELLCPDNTRKPISDYKNCNLAKVPAHSVLARARDDKSKDIIAFLQEAQKTKECKLFSSQHGKDLLFKDTAVSLVPLPPTIDGFLFLGAVYYQEIHALKEGVKEDDLAAPSKVRWCTQSKAEKTKCDDWTTISGGSIECTEAATAEDCILQILKGDADAVTLDGGYMYTAGQCGLVPVMGEYYDLDDLTPCQRRSSQAKGVYYAVAIAKKGTKVSWKNLRGVKTCHTAVGRTAGWNIPVGLITNETNNCDFASYVGESCAPGSDVKSNLCKLCIGDPAKPLDSAKKCSPSASEAYHGYSGAFRCLVEKGDVCFAKHTTVFENTDGKNPAAWAKDLKSDDYELLCPDGSRAPINDFKRCNLAEVPAHSVVTLPGKRKPVVEILVNQQSLYGRKGFQKDIFQMFQSKDGKDLLFKDSTQCLLEISEKTTMQEFLGDKYYTAVTSLNKCSNTKSGLLSSCTFHSC
What is the function of this protein?
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.  It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization.  Serum transferrin may also have a further role in stimulating cell proliferation (By similarity).
What are the official names of this protein?
Serotransferrin.
What is the protein family that this protein belongs to?
Belongs to the transferrin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BCSQP_ECOLI
Sequence: MRGGVGTTTITAALAWSLQMLGENVLVVDACPDNLLRLSFNVDFTHRQGWARAMLDGQDWRDAGLRYTSQLDLLPFGQLSIEEQENPQHWQTRLSDICSGLQQLKASGRYQWILIDLPRDASQITHQLLSLCDHSLAIVNVDANCHIRLHQQALPDGAHILINDFRIGSQVQDDIYQLWLQSQRRLLPMLIHRDEAMAECLAAKQPVGEYRSDALAAEEILTLANWCLLNYSGLKTPVGSAS
What is the function of this protein?
A C-terminal pseudogene fragment of BcsQ, which has a premature stop codon at position 6 of the intact protein.  The mutation prevents cellulose synthesis, and has polar effects on transcription of downstream gene bcsA and probably also bcsB, bcsZ and bcsC (PubMed:24097954).  When the reading frame is restored cellulose biosynthesis is also restored, see (AC P0DP92) for an intact protein.  May play a role in subcellular localization of an active cellulose biosynthesis apparatus at the bacterial cell pole (By similarity).
What are the official names of this protein?
Putative cellulose biosynthesis protein BcsQ.
What is the protein family that this protein belongs to?
Belongs to the BcsQ family.
Protein: PSB2_HALTV
Sequence: MNNWSQGSTPQGSDPSPYAPELGSLPDGSQSDDHGDTVNKTGTTTIGITTDEGVVIATDMRASLGGRFVSNKNVQKVEQIHPTGALTLVGSVGGAQSFIRTLRAEVNLYESRRGEPMPIEALATLAGNFARGGPFRAINPILGGVDEEGSHVYSIDPAGGVMADDYTVTGSGMQLAYGLLEQEYEEGLSLEEAQSVAARAIESAVERDTGSGNGVFLAAVTGEGVDIQGHNDFDAVI
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_BURP0
Sequence: MNLNATLFAQMVVFLVLAWFTMKFVWPPLINALDERSKKIADGLAAAEKGKAELEAAHKRVDQELAQARNDGQQRIADAEKRALAVADEIKTNAQAEAARIIAQAKAEAEQQIVKARETLRGEVAALAVKGAEQILKREVDQTAHAELLNQLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL27_SHIDS
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CLPP_LACCB
Sequence: MLVPTVVEQTSRGERAYDIYSRLLKDRIIMLSGEVNDQMANSVIAQLLFLDAQDSEKDIYLYINSPGGVITSGLAMLDTMNFIKSDVQTIAIGMAASMASVLLAGGTKGKRFALPNSTILIHQPSGGAQGQQTEIEIAAEEILKTRRKMNQILADATGQTIEQIKKDTERDHYMSAQEAKDYGLIDDILVNKNTQK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_SALPA
Sequence: MAAQGFLLIASFLLILLVLAKPLGSGLARLIAAVPLPGVAGVERILWRTLGITDHEMNWRQYLLALLTLNLLGLGILFCLLFWQEWLPLNPQRLPGLSWDLALNTAVSFVTNTNWQAYSGESTLSYFSQMAGLTVQNFLSAATGIAVVFALIRAFTRQNVHTLGNAWQDLVRITLWILFPVALIIALFFIQQGVPQNLSAYQPITTLEGAKQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNLAQMLAIFLIPAALCFAFGEAAGDRRQGRALLWAMSFIFVVCVAVVMWAEVQGNPHLLAAGADSSVNMEGKETRFGVLASSLFAVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKMTALAILVTPMLVLLGSALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKVQPASQGTLATHGALFIGLLIGTVLLVGALTFIPALALGPVAEHFSLP
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMP_ACIC1
Sequence: MPTSTGAQRLAELLAPVVAGQGLDLEGVTLLDHRTSAHLRIVVDKDGGVQLDEIAAASQAISHFLDNDAEADAIIGPRSYTLEVSSPGIDRPLVEPRHWRRAIGRLVRVQLPDLGPVVARVQDVTGDQVRLGIEWQYTDDGACVRQYEERTVAIAEVRPGQIEVEFEEHP
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLHA_BALAC
Sequence: FPBGZFTMZGCPZCKLKZBKYFSKLGAPIYZCMGCCFSRAYPTPARSKKTMLVPKNITSZATCCVAKAFTKATVMGBARVZNHTZCHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_ECOL6
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX41_MOUSE
Sequence: MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAAAAAAAASGFPLAPEPAALLAVPGARREVFESTSFQGKEQATGPSPAGPHLLHHHHHHAPLAHFPADLVPASLPCEELAEPGLVPAARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPCSGPSSASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEVVQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGRGGGGSASGPGVRGPGRMREHHAGSAVPSTYAVSRHGSSPSTGASSRVPAASQSSGCYDSDSLELPRPEEGPSEDSGPGGLGSRAQATNGGSERSQAPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPSDVPRPGPAVAGPLNSCRLSARPEGGSGRGRRVERGSPSRSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCRDIVSLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQALRRRPGFSKILHIKVEGGC
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
F-box only protein 41.
Protein: DNLJ_CAMFF
Sequence: MDKNDYLKAVDSLNLWAKAYYTDDSPMASDDEYDKLYNAVVQFEKENPDLKLSYSPTNRIGGEILDEFKKISHIEKMWSMEDIFSDSELVAWISRGDKTDCEFFAEPKFDGASLNLLYENGNLISAATRGDGSVGEDVTNNAKVISSVPLQIDYKDKIEIRGEVVITKDDFELINIERSKNSEPPLANPRNAAAGSLRQLDNGIVKQRKLKFYPWGVGENSLKFNKHSQIMDFVRSLGFLHDNFCKVIRGIDELKIAYKELLSVRELKPILMDGMVIRVNDLSKANQLGYTVKFPKFMVAYKFPATEKTARLIDILLQVGRTGVVTPVGLLDGVLIDGAFIKNVTLHNFDEIDRLNLMKNDFVTVIRSGDVIPKITGVFKDRRDGSQSEIIRPKICPKCGNELLDEGVFIKCQNLTCKARVVSSIIYFASKKCMNIDGLGDAIVELLYQKNIIKDIADIYRLDELSFIGLEGFKTKKISNLLSAINNSKTPNLDKFIASLGIEHIGEVAAKKIANNYGDRWLELTLEELLALDGFGEAMALSYLEFMRVNLEKIKELLEFITPKMQNLELKTNIFSGKTVVITGTLSRSRDEFKAELESYGAKVSSSVSKKTDFVLYGNEAGSKLEKANELGVRAIDESEYESLK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: COBQ_ALBFT
Sequence: MTAKCIMVLGTTSGAGKSWLTTALCRYYARQGLKVAPFKAQNMSNNARVVASDKGSGEIGSAQYFQALAARSVPDVRMNPLLLKPEADTHSQVVLMGRVSDALTAMPWRSRSNHVWPHIAAALDELRSENDVVVIEGAGSPAEINLSGSDIVNMRVARHCDAACLLVTDIDRGGAFAHLYGTWALLPERERVLIKGFVLNKFRGDAALLAPAPQMLQDLTRIATVATLPMWWQHGLPEEDGVFDDRSTASGAVKQTVAVIAYPRISNLDEFQPLKNIPGLRLMWVRSPAELAGLSASDWVILPGSKATSSDLAWLRAQGLDAAVAAHAGRGGAVLGICAGLQMLGKALIDPQGVDGDAPGLGLLPLVTVFELDKTVRHTQATFADGIAAPWHALAAVTVSGYEIHQGITQPQSTPATAGEVARAVLPGGLAWQNAAGNVLGLYLHGLFEDPGALQALFGAQLNGPVPTLDVVFDRLADFIELHFQPGVLPGLLT
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: NADK_SALNS
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMBT_DROPS
Sequence: MNPTELHMMWMSSQYNAANNMTLEDATALLNHPTVGLLEEMSGHHHQPTLEMNPMMGLVGGDFNGHAATLSGTLPPGTLIATNSNNLYSFAHLGGLQHQLLQQSAAVAAFQNYTEVMDADGMTVGLATDPHGELMDETCDDEDQVYGHQIDDGYDDGGAGLEPKQEIINIDDFVMMNEDNNSYDGTDFMTSSDKDISQSSSSGLTHMQGGGVSLGVAGAEHDLLVPLGDGLMHHKLLGATLAPAMPLNVGNSNVFGNIMVTGADPPSSKQMKGYRNSNSSGTSSATVTTVASTAVMRAQRKTRKIEPVNRPGLVLKTPIAYKGNIDPSVIPIQKDGMAVCERCGAIGVKHTFYTKSRRFCSMACARGELYSLVLNNKMETTGATTSNNQSTSSSPLPAASGTSLDVTEDALLASDQPQSDIELDLHAAHIKNANYRFRITDQSKITQLNSFGEPMSLGGDAAAHNVQMAADETIAALNGAAVGDAAAPGGEANGSGNDTSTPNTASSGYLSAAPTPKALRLFKDVYPQDDLPQIPKYERLPAPCPQMEKVLSIRRRMYDPTHSYDWLPRLNKENFNAAPVTCFPHAPGCEVWDNLGVGMKVEVENTDCDNIEIIQPGQTPTSFWVATILEIKGYKALMSYEGFDTDSHDFWVNLCNAEVHSVGWCATRGKPLIPPRTIEHKYKDWKDFLVGRLSGARTLPSNFYNKINDSLQSRFRLGLNLECVDKDRISQVRLATVTKIVGKRLFLRYFDTDDGFWCHEDSPIIHPVGWATTVGHNLAAPQDYLERMLAGREAMIEVHEDDATIELFKMNFTFDEYFLDGKTNGFIEGMKLEAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPDESGSDWFCYHEKSPCIFPAGFCSANNISVTPPNGYDSRTFTWEVYLRNTGAVAANQHLFHRVVPEHGFETGMSLECADLMDPRLVCVATVARVVGRLLKVHFDGWTDEYDQWLDCESADIYPVGWCILVGHKLEGPPRVSYQQVAKPAPKPKVPRKKKTKKGASTTGGGAAKQQNDNTQTTQTVKPRTIALKTTPHLPKLSIKLELKPEHHNAAFYENNQPEDGDGDEEDPDPDADADLDADADGDGDGSTSHISEQSTTHSSSDQILGSGSGGGSTSAPVVTAATGSIGGNSNKMNSSATSSKYIPRLADIDASEAAHLELQPDSWNVYDVSQFLRVNDCTAYCDTFSRSKIDGKRLLQLTKDDIMPLLGMKVGPALIISDLITQLKCKVNPGRARSHKTNKSSYL
What is the function of this protein?
Polycomb group (PcG) protein that binds to the Polycomb response elements (PREs) found in the regulatory regions of many genes.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility.  Necessary but not sufficient to recruit a functional PcG repressive complex that represses target genes, suggesting that the recruitment of the distinct PRC1 complex is also required to allow a subsequent repression (By similarity).
What are the official names of this protein?
Polycomb protein Sfmbt, Scm-like with four MBT domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARTM_ECO57
Sequence: MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN
What is the function of this protein?
Part of the ABC transporter complex ArtPIQMJ involved in arginine transport.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Arginine ABC transporter permease protein ArtM.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.