PharMolix/UniProtQA huggingface dataset:
Protein: ZAR1_RAT
Sequence: MFPASTPHPCPHPYPPTAAKAGDGWRFGARGCRPEPPSFLPGYRQLMAAEYFDSYQRAQLMALLSRMGPRPVSSRDAAVQVNPRRDASVQCSLGRRTLQPGRRRASPDARPGSCQPRSPARAGRPPRSWRTVALYSPVTFGGLSSSLEVAGDRQTPTKGEGRPAPTGTREPEPGEVAVMKAVPQPQSEEGDVQAEGQDGQEQPPREDPDSVAAMQSEPGSEEPPPAVEMAQDPSDVAASRDRASPQSTEQDKERLRFQFLEQKYGYYHCKDCNIRWESAYVWCVQGTSKVYFKQFCRVCEKSYNPYRVEDITCQSCKRTRCACPVRLRHVDPKRPHRQDLCGRCKDKRLSCDSTFSFKYII
What is the function of this protein?
mRNA-binding protein that mediates formation of MARDO (mitochondria-associated ribonucleoprotein domain), a membraneless compartment that stores maternal mRNAs in oocytes.  MARDO assembly around mitochondria is directed by an increase in mitochondrial membrane potential during oocyte growth.  Promotes formation of MARDO phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to maternal mRNAs.  Binds to the 3'-UTR of maternal mRNAs.  Maternal mRNAs stored in the MARDO are translationally repressed.  Essential for female fertility and oocyte-to-embryo transition by coordinating maternal mRNA storage, translation and degradation.
What are the official names of this protein?
Zygote arrest protein 1.
What is the protein family that this protein belongs to?
Belongs to the ZAR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I35A1
Sequence: MATQGTKRSYEQMETDGERQNATEIRASVGKMISGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRVDGKWMRELILYDKEEIRRIWRHANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMVDQVRESRNPGNAEVEDLIFLARSALILRGSVAHKSCLPACVYGPAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTKSGGNTNQQRASAGQISIQPTFSVQRNLPFDRSTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKAASPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: DUT_RICAH
Sequence: MNITQVKIKKLENFSGSLPEYATEHSAGMDLIAANEQPITIKAGEIQLIPTGIAIALPYSFEAQIRPRSGLAVKHGITVANSPGTIDADYRGEIKVILINLGTQDFVIEKGMRIAQIIISKYERILWEESSILTETMRGSGGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: TYSY_HALH5
Sequence: MEQYLELCRHVLEHGTERSDRTGTGTISVFGYQMRFDLQEGFPVVTTKKLHLRSIIHELLWFLKGETNIAYLQENGVRIWNEWADENGELGPVYGKQWRSWEGANGKTVDQISQVVEAIKHQPDSRRLIVSAWNAAEIEDMALAPCHCLFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTKMIAQVCDLEEGEFVHTFGDAHIYLNHIEQVKLQLTREPRPLPEMRLNPEVRSLFDFTFDDFELVGYDPHPHIKGEVSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
Protein: MEND_HISS2
Sequence: MSASVFNRCWSKVILETLSRQGVSHFCIAPGSRSTPLTLEAIRLQENGRGTCHTHFDERGLGFFALGIAKASKKPVAVIVTSGTATANLYPAIIEARQTDVPLIILTADRPPELLECGANQAILQQNMFAQYPIASINLPRPSQNYSAQWLISVLDQACFRQKQGGVIHINVPFAEPLYNANNDEIDLHPWLSNIQSWLTQNKNWIQHQEQHTEVITHKYWDQWRTKKGIIIVGRLPSEQAMGIAEWAENMGWIMITDIQSHVKPTLPYADIWLANQTVRKKLLQAEIVIQFGSGFIGKRINQFLAEFKGEYWIIENNQKAVDPYHHAHTRFNAKPHHWLRAHPPMRKKPWLLEPLALAKFCADFIKQRVGSNLNEASLAHNIELLLPKSNSVLFLGNSLFVRLADALSQPSANYPIYTNRGASGIDGLLATAAGIAVGSEQTLVAMIGDTSTLYDLNSFALFKQLNQPAIIFVINNNGGAIFDMLPVDIAVKEKYYRMSHYLEFSHIAAMFDLKYARPYTWADLATVLKQAYSRRETTIIEIKINPNDGSNIYKDLIDKIGHALIGV
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: ZN277_MOUSE
Sequence: MAASEVQGLPVDPREAGVRGVRGGIGHTDHEGHLGSFQLLATINKAAMNIVEHVSFLPVGTSSGYIAASSGITMSNFLRNRQTDFQSGCTSLQSHQQWRSVPLSPHPHQHLLSPEFLILAILTGVRWNLRIALICISLMIKDAEHFFRCFSAIWYSSDSKDCILEPLSLPESPGGTTALEGSPSVPCIFCEEHFPMAEQDKLLKHMIIEHKIVIADVKLVADFRRYILYWRKRFTEQPITDFCSVIRINSTAPFEEQDNYYLLCDALPEDRILREELQKHKLKEVLDQQQRERNDTSFHGVCMFCSEEFRGNRSVLLNHMAREHAFNIGLPDNIVNCAEFLCTLQKKLDNLQCLYCEKTFRDKNTLKDHMRKKQHRRINPKNREYDRFYVINYLELGKSWEEVQSEDDRELLDLQEDDWSDWQEYPVSAVCLFCEKQEETIDKLYVHMKDTHEFDLLRIKSELGLNFYQQVKLVNFIRRQVHQCKCYSCHVKFKSKADLRTHMEDTKHTSLLPDRKTWDQLEYYFPTYENDTLLCTLSDSESDLTAQEQTENVPVISEDTSRLCALKQSSVLNQLLLQGCLEN
What is the function of this protein?
Probable transcription factor (PubMed:20808772).  Involved in modulation of cellular senescence; represses transcription of the tumor suppressor gene INK4A/ARF, perhaps acting via the Polycomb group (PcG) complex PRC1 (PubMed:20808772).
What are the official names of this protein?
Zinc finger protein 277.
What is the protein family that this protein belongs to?
Belongs to the ZNF277 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nucleolus. Chromosome. Note=Probably localized to nucleolus and cytoplasm in complex with 40S ribosomal protein S2/RPS2.
Protein: YGX1_SCHPO
Sequence: MINKKLLFLVFALAKGVLADEEDEYEEDYNMNPELENPGMFKHVDWRDFRLEFVILACFFLYVFSFITQKKKNQKIASRWYGSLQSSFRQQFAQYGPGPNSSPIIYDSPTEFSSYLTGRLNVKNVYTTLQLFPRQDLLAYSLNQIVEILLGNVMSSVLPVADRFQFDLTLADQNLKAERFVFAIVHKDCMRILREIRYDLSFTRISSSPYLPETHVLMSENNECSQAIFEIPEFMSSINECIENLEYFIVTDQPSVPPATEKDYVTKPRIEASIRIKKITSLSGLSNATGSALFNSLLLVADSCPKFQWRPEVSKKLTSARKLAFEQVVHASAAKAAKKKVKSSGDISKLSESDQKKRMERERQRKMRRRAKKM
What are the official names of this protein?
UPF0674 endoplasmic reticulum membrane protein C2G5.01.
What is the protein family that this protein belongs to?
Belongs to the UPF0674 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: KTHY_PSET1
Sequence: MKPKFIVIEGLEGAGKSTAIALCQSFLNSKKIDFINVREPGGTPLAESLRTLVKAQHDEEIAFETELLIMYAARSQLMHNVINPALEQGQWVLADRHDLSSQAYQGGGRGISANTLASLSSMVLKGLKPDLTIYLDIDPVIGLERAKGRGELDRIEQEAIEFFQRTRMRYLELANDDNSIKTVDANQSIEHVHRDITNVLRTFFAEQK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: EFTU_BRUSU
Sequence: MAKSKFERTKPHVNIGTIGHVDHGKTSLTAAITKFFGEFKAYDQIDAAPEERARGITISTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPAIVVFLNKCDQVDDAELLELVELEVRELLSKYEFPGDEIPIIKGSALAALEDSSKELGEDAIRNLMDAVDSYIPTPERPIDQPFLMPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIKATTKTTVTGVEMFRKLLDQGQAGDNIGALIRGVGREDVERGQVLCKPGSVKPHTKFKAEAYILTKDEGGRHTPFFTNYRPQFYFRTTDVTGVVTLPAGTEMVMPGDNVAMDVTLIVPIAMEEKLRFAIREGGRTVGAGIVSSIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTS3_MYCBO
Sequence: MKLNRFGAAVGVLAAGALVLSACGNDDNVTGGGATTGQASAKVDCGGKKTLKASGSTAQANAMTRFVNVFEQACPGQTLNYTANGSGAGISEFNGNQTDFGGSDVPLSKDEAAAAQRRCGSPAWNLPVVFGPIAVTYNLNSVSSLNLDGPTLAKIFNGSITQWNNPAIQALNRDFTLPGERIHVVFRSDESGTTDNFQRYLQAASNGAWGKGAGKSFQGGVGEGARGNDGTSAAAKNTPGSITYNEWSFAQAQHLTMANIVTSAGGDPVAITIDSVGQTIAGATISGVGNDLVLDTDSFYRPKRPGSYPIVLATYEIVCSKYPDSQVGTAVKAFLQSTIGAGQSGLGDNGYIPIPDEFKSRLSTAVNAIA
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS 3, PBP 3, PstS-3, Antigen Ag88.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TXS4F_CUPSA
Sequence: VYGMLFKFL
What are the official names of this protein?
Short cationic peptide-4f, SCP-4f, Short cationic peptide-4g, SCP-4g, Truncated variant of Cupiennin 4 family.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 08 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL3_NITMU
Sequence: MSLGLVGRKVGMTRIFTEEGDSQPVTVLDVSNNRVTQIKTPATDGYSAVQVTFGKRRAIRVNKPSAGHFAKAAVEAGEILREFRVAEEILGTLSPGTVIGLDIFQPGQRVDVTGTSIGKGYAGAIKRHGFASNRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHLGNVRRTIQNLEILRIDAERGLLIIKGAIPGSKGGDVTVSPSIRSARPTNNGNVNAAAKGGAKSGKKGG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RLMG_CROS8
Sequence: MSQVELLNQTLTLQRFPPMPEETPLQAWEAADEYLLQQVEQPSGPVLIFNDSFGALACALAEVRPVSVNDSFIAHQATRHNLRLNDIDDSLVTMQDSLSPLPDAPELVLMKIPKQLALLEQQLRALRKVVTPQTRIIAGAKARDIHTSTLTLFEKILGPTTTTLAWKKARLIHCAFSAPALADAPETLSWKLDGTPWTIHNHASVFSRTSLDIGARFFMQHLPEAVEGEMVDLGCGNGVIGLTLLAQNPQAKVRFVDESYMAVASSRLNVETNLPEAMERCEFQVNNALTGVEPESFHAVLCNPPFHQQHAITDHIAWQMFQDARRCLKWGGELRIVGNRHLDYFRKLKKIFGNCTTVATNNKFVVLKAVKLRKSR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_ACIAC
Sequence: MKLCGFDVGLDRPFFLIAGPCVIESEQLQMDVAGRLKETTAALGIPFIFKSSFDKANRSSGTSFRGPGREKGLEILAKIRRELNVPVLTDVHTEDDITEAAKVVDVLQTPAFLCRQTDFIRAVAQSGKPVNIKKGQFLAPHDMKNVIDKARAAAREKGLPEDSFMACERGASFGYNNLVSDMRGLAIMRETGAPVVFDATHSVQLPGGQGTSSGGQREMVPVLARAAVAVGVAGLFMETHPDPCNALSDGPNAVPLKHMKALLETLVALDSVTKRNGFLENDFGA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y657_PELPB
Sequence: MSGHSKWATIKRKKAVTDQKRGSLFTKLVKEITIAAKMGGGDPAGNPRLRLAIDTARDNSMPMDNIQRAIKKGTGELEGVTWDEITYEGYGPAGIALIIETATDNRNRTVADIRHIMSRNNGSLGESGSVAWMFQRKGTLDVPRSAAGEDQLMELLLEAGLEDLGSDDENYFTVITDVKDLERVKKALDDAAIMYENAKIDLIPENYIELEAEDARKVIKLIDAFENNDDVQAVYTNMEISESAMSSLNE
What are the official names of this protein?
Probable transcriptional regulatory protein Ppha_0657.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERF5_TOBAC
Sequence: MASPQENCTTLDLIRQHLLDDNVFMEHYCPQPILYSQSSSSSESLNSIASELNNETFSFEPTLKYADTAQSSNLDISSFFNNSKTEFDSFEFETKPNVSAARISSNSPKQTSFKERKPSLNIAIPMKQQEVVQKVEVVPTEKKHYRGVRQRPWGKFAAEIRDPNRKGTRVWLGTFDTAIEAAKAYDRAAFKLRGSKAIVNFPLEVANFKQQDNEILQPANSGRKRMRETENEEIVIKKEVKREERVPAAAAPLTPSSWSAIWEGEDGKGIFEVPPLSPLSPHMAYSQLVMI
What is the function of this protein?
Acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways mediated by ethylene, that seems to depend on a protein kinase/phosphatase cascade, and to be influenced by methyl-jasmonate.
What are the official names of this protein?
Ethylene-responsive transcription factor 5, Ethylene-responsive element-binding factor 4, EREBP-4, Ethylene-responsive element-binding factor 5 homolog, NtERF4.
What is the protein family that this protein belongs to?
Belongs to the ethylene-response factor family. Class 3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SOR_PYRFU
Sequence: MISETIRSGDWKGEKHVPVIEYEREGELVKVKVQVGKEIPHPNTTEHHIRYIELYFLPEGENFVYQVGRVEFTAHGESVNGPNTSDVYTEPIAYFVLKTKKKGKLYALSYCNIHGLWENEVTLE
What is the function of this protein?
Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
What are the official names of this protein?
Superoxide reductase, SOR.
What is the protein family that this protein belongs to?
Belongs to the desulfoferrodoxin family.
Protein: ATPD1_VIBC1
Sequence: MSDMTTIARPYAKAAFDFAVDKDQLDQWGQMLSFATEVTKNEQMNELLKGSVSADKLAEIFVAVCGEQVDAHGQNLIKVMAENGRLTALPDVCEQFFLLKKEHEKEIDVEVISASELSDEQLANIGSKLEVRLERKVKLNCSVDETLLGGVIIRAGDLVIDNSARGRLNRLSDALQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta 1, ATP synthase F(1) sector subunit delta 1, F-type ATPase subunit delta 1, F-ATPase subunit delta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FBIA_MYCBP
Sequence: MKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDDRCETHVVITDPVDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSSAATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGDHAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA
What is the function of this protein?
Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
What are the official names of this protein?
Phosphoenolpyruvate transferase, EPPG:FO PEP transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: SYL_BURA4
Sequence: MHERYVPADVEAAAQGDWRAADAYKTREDSQKPKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAKWTYDNIDYMKGQMQSMGLAIDWSREIATCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPMYYLRITQYADELLNDLDGLGWPERVKIMQQNWIGKSFGVNFGFPYELDGEKALLRVFTTRADTIMGVTFCAVAAEHPLATRLAQGKPELQAFIDECKRGGVAEADVATMEKKGVATGFSVSHPLTGEPVEVWIGNYVLMSYGEGAVMGVPGHDERDFAFAKKYGLPIKQVIASEGQTYSLDAWQEWYGDKETAVCVNSGKYDGLRYADAVDAVAADLKAGGYGDKQVTWRLRDWGVSRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDLVPDGSGNPLAKSEAFLNCSCPKCGAAAKRETDTMDTFVDSSWYFSRYTAPDADTMVDARTDYWMPMDQYIGGIEHAILHLLYSRFWTKVMRDLGLVKFGEPAKNLLTQGMVLNETFYREDASGKKTWYNPADVTVTHDDKGRPVGATLNTDGQPVVLGGIEKMSKSKNNGVDPQVLIDQYGADTARLFTMFAAPPEQQLEWSGAGVEGASRFLRRVWSFGATNREALAARAGFDAAALGDADKALRREIYSVLKQADFDYQRLQYNTVVSAAMKMLNAIDGAKGATPAVLRETYGVLLRVLYPVVPHVTFELWKALGYADEFGPLLDAPWPKVDEAALEQAEIELVLQVNGKVRGALKVAKGASRDAIEAAAVADEAFAKFSDGKPAKKIVVVPGRLVNIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_I01A0
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEIVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEIFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRLNKKSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSVEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: RRP1_DICDI
Sequence: MEEETKVVKKVTGPAKPQKLRSIDVELAQKLNTGSSQTKSSALYKLRSVVKNEKLTEIQLLKIWKGLFLSLYNTDKPIVQEEFSRDISKLTTYFKDYKDSLMFIKCFFIILQKHWDYIDKYRVDKFYSLVRKMLNSSFQILKKRNAQHEEGSEEEEARLALNEQIYSGLVKIFKSTVLNTSSDSTTNTNGVLLHFADIYLEELFKVTQGHMEPINLTKILLPFVNFLTKSEDDVSCKRIKERVFDRLLTTYSPFDKKDAYYLPKVGVSSSTPEIFPTDYEMFSKLFFKCASSKDTLEQNRKTLYGLKNQFKRAQAALEELEELADNIVLDENGDIVENPNVNPEDLQGDDSDDSDEEFDVDQMDSEDSGEGEFDDEIDADDAEELDDDDDEEFDEELDEEDEEEEEEEEEEVPPPPPTKNLKSKPSPVTQKNKQQQQQPPAKPAPITKKQQQSPAKPTQVTKKQQSPAKPTPVTKKQQSPVKPTSPKVVKKPTRK
What is the function of this protein?
May be involved in the generation of 28S rRNA.
What are the official names of this protein?
Ribosomal RNA processing protein 1 homolog, RRP1-like protein.
What is the protein family that this protein belongs to?
Belongs to the RRP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MRED_STRR6
Sequence: MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLFLLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRWTRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFEKYYL
What is the function of this protein?
Involved in formation and maintenance of cell shape, probably part of the elongasome which synthesizes peripheral peptidogylcan (PG).
What are the official names of this protein?
Cell shape-determining protein MreD.
What is the protein family that this protein belongs to?
Belongs to the MreD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MDH_CAUSK
Sequence: MARAKIALIGAGMIGGTLAHIAAREELGDILLFDIAEGTPQGKALDIAEASAVFGKDVSLKGVNDYADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKAVGEGIKAHAPNAFVICITNPLDAMVWALQQFSGLPKEKVIGMAGVLDSARFAFFLAEKTGVSVEDIHAWTLGGHGDDMVPMVRHSTVGGLPLPELVKQGWLSQEELDGIVKRTRGGGGEIVALLKTGSAFYAPAESAIAMATSYLKDKKRVLPCATFLTGQYGLDGLYVGVPVVIGAGGAEKVIEFETNDEEKAMFAKSVESVKGLMEACKAIDSALV
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: SYFB_RHORT
Sequence: MKFTIGWLKDHLDTQASVADIAEKLTALGLEVDAIEDPTAALAPFVVGHVIEAGPHPDADRLKLCRVDSGTDILQIVCGAPNARTGLKVALALPGAVIPATGDVLKKGKIRGIESQGMMCSTRELGLGEDHDGIIELPADTPVGVPLVDVLALDPVIDIAITPNRADALGVRGIARDLAAGGLGGVIADTLTAIPGRFPSPIGVAIDPETLASGACSHYVGRYFRGVRNGESPAWLKDRLNAIGVRPISLLVDITNYVTFDRARPLHVFDADKLTGTTITARPARQGEILRALDGRSYTLDAPVVAIADGAGPQGLGGIMGGEDTGVDENTVNVFLESALFDPANTAAAGRFLGIDSDARYRFERGVDPESCLLGAELATRMILDLCGGEASELVIAGAPPVWRRTIALRPARVARLGGVAVERAEMVAKLRALGCTVEDDGAEALRVDPPSWRVDIGAEHDLIEEVVRLHGFDLVPAVPLPRDPMPKAVLTPGQRRMITVKRTLATRGMLEAVTWSFLPRAVAKGFGGGQDALVLANPISSDLDAMRPSILPNLIAAAGRNAARGYGDLGLFEVGPRFHGGEPGQQTLVAAGLRAGKIAPRHWSRPARDADLYDIKADVLAAIEAAGAPTASLQVSADAPAWFHPGRSGQIRLGRTVLAAFGEIHPAALALLDVKGPMVGFELDLDALPLPKGRPSKTRPPLTLSPFQPVARDFAFVVEAGVAGDAVIKAARGADKALITDVVIFDVYQGDRLEAGRKSLALSVTLQPTDHTLSDEEIEAVSARIVGAVTKLTGGSLRS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG058_VAR67
Sequence: MKHKVYSEGLEISTDFNSIISQLSTSDMDIEIDEDNITELLNILTELGCDVDFDEDFSDITDDVLESLMEQDM
What are the official names of this protein?
Protein OPG058, Protein F14.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG058 family.
Protein: COX19_CRYNB
Sequence: MSFGRPGFADVFKPSPPARGSFPLDHDGECKAFMISYLKCMKENANDNGKCRLFSKQYLECRMDKGLMARDDMANLGLGDVVDPSALPPASTQTTTAPLSNPPHVPQPPSSEHRI
What is the function of this protein?
Required for the assembly of mitochondrial cytochrome c oxidase.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX19.
What is the protein family that this protein belongs to?
Belongs to the COX19 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.