PharMolix/UniProtQA huggingface dataset:
Protein: PA2A_NOTSC
Sequence: MYPAHLLVLLAVCVSLLGAASIPPLPLNVAQFDNMIECANYGSRPSWHYMEYGCYCGKEGSGTPVDELDRCCKAHDDCYTEAEKRRCHPKFSAYSWKCGSDGPTCDPETGCKRTVCDCDATAAKCFAKAPFNQANWNIDTETHCQ
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE_SYNS9
Sequence: MSLTLRVLAPDQNVFDGSADEVILPSTTGQLGILTGHISMLTAIDVGVLRVRANGSWNSIALMGGFAEVDSDEVTVLVNKAELGSSIDANAAEADFQKATTAVAGMEGQPASPEKVKAQQQLNEARARMQASKSAD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RAG3E_ARATH
Sequence: MPSRRRTLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVQFEDRLFTLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVNSAKSFEDLNNWREEFLIQASPSDPENFPFVVIGNKIDVDGGSSRVVSEKKARAWCASKGNIPYYETSAKVGTNVEDAFLCITTNAMKSGEEEEMYLPDTIDVGTSNPQRSTGCEC
What is the function of this protein?
Intracellular vesicle trafficking and protein transport.  May play a role in adaptation to stress by recylcing macromolecules in specific cellular compartments.
What are the official names of this protein?
Ras-related protein RABG3e, AtRABG3e, Ras-related protein Rab74, AtRab74.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: SNPF_CAMFO
Sequence: MSAMYAKRCAALVLLVVTVGLVNATENYMDYGEEMAEKTPAENIHELYRLLLQRNTLDNAGFGGIPLEHLMIRKSQRSPSLRLRFGRSGPHVSARALPRPMGAVAGYDDNN
What is the function of this protein?
Plays a role in controlling food intake and regulating body size.
What are the official names of this protein?
Short neuropeptide F, sNPF.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: ULAD_SALEP
Sequence: MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAESPVEAARQFKRSIAQLWG
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
3-keto-L-gulonate-6-phosphate decarboxylase UlaD, 3-dehydro-L-gulonate-6-phosphate decarboxylase, KGPDC, L-ascorbate utilization protein D.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: RPOB_XANC8
Sequence: MEDLMTSYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYREFLQEDVEPNKRKDLGLHAALKSVFPISSYSGNAALEYVGYKLGEPVFDERECRQRGMSYGAPLRVTVRLVIYDRESSTKAIKYVKEQEVYLGEIPLMTENGTFIVNGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDALFTRIDRRRKLPVSILLRALGYNNEEMLAEFFEINTFHINPDEGVQLELVPERLRGETLNFDLADGDKVIVEAGKRITARHVKQLEAAGVAALAVPDDYLVGRILSHDVVDGSTGELLANANDEISEDQLAAFRKAGVDAVGTLWVNDLDRGPYLSNTLRIDPTKTQLEALVEIYRMMRPGEPPTKEAAQNLFHNLFFTFERYDLSTVGRMKFNHRVGRKEVLGESVLYDKKYFAERNDEESKRLVAEHADTSDILEVIKVLTEIRNGRGVVDDIDHLGNRRVRSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLSRFMDQNNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLINSLAVFARTNQYGFLETPYRKVLDGKVSDDVEYLSAIEENEYVIAQANALTDAKNMLTEQFVPCRFQGESLLKPPAEVHFMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPTLRSQKPLVGTGIERAVARDSGVTVNARRGGVIEQIDAARIVVKVNEAEIGGGTDAGVDIYNLIKYTRSNQNTCINQRPLVNVGDVIARGDVLADGPSTDIGELALGQNMLIAFMPWNGYNFEDSILLSERVVEEDRYTTIHIEELTCVARDTKLGPEEISADIPNVSEQALNRLDESGVVYIGAEVRAGDIMVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDVQVFTRDGIEKDKRARQIEESEIKRVKKDFDDQFRILEAAIYARLRSQIVGKVANGGPNLKKGDNVTDAYLDGLKKSDWFQLRMKDDDAADAIERAQKQIQAHEKEFEARFADKRGKITQGDDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNVVPVEDMPYMATGEPVDIVLNPLGVPSRMNIGQILEVHLGWAAKGLGRKIQRMLEAQTAVSELRKFLDDIYNHDSAINAERVDLSQFSDEELLNLGKNLIDGVPMATPVFDGASEAEIKRMLELAELPQSGQTQLYDGRTGEAFDRKTTVGYMHYLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGEHEMVAGMPESFNVLVKEIRSLAINMELEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MIG1_MAGO7
Sequence: MGRRKIEIKAIKDDRNRSVTFLKRKGGLFKKAHELSVLCSVDVAVFIFGTNKKLYEYSSGDMRELITRYTYHGGATEHKGPSDFNGGDDDDEEEGDGTPPLDQPMDAHMMPPHFQGQGPFPPHVMRHYTPSASPPIPNGVPFPPHGHGVPRGHTPQPQMLSRPGSRNDARRMGQPMGPQGSPQVNGFGFGQQQSMYGPPNTTMPPHMPPQMAPGPPFPYPQHPQHPPHPPHPPHPPHPQQPHQPQMQQQFIEDGRRATMPANFAPHPPPPHGPMGMQRHSVSPPQQHPHHVPQLPPQQPQQHPHSSPPQPQHHQMQSPPQPMVKFESPQQIEPPQHQHQQQPEPQEPRPEQQQQQQQSQQSQQPQEPQSEPARSLPPPPPPLEVKTELAPPAQPGRIPQPSLLDTAVKKLPRQKQHSIFTPIDENRSILSQNLAAFHAEPSKNKSSPPAHHRSSSVDESTSNASEASRGKDKDIASSPPLLKRADPRASISSVSSAPESAPAPPSRSNSLRAGPPRPRLKVQIPDEQSEDGSGSATAESASSAQGGASTDATSQSTRQNDSHSSTNMVLPPPSPSASALLSAGATGPPNPFAPKRPPQHPAPGLNIDTPVSALPSRFLNNEFLPSPSSFYPDWNFRGGDNNTLPSPLNFATPVVGTGPSFLRDENPGASLKRKSPDNLSIHGPISDNPLEAGNEPKRVKVDS
What is the function of this protein?
Transcription factor acting downstream of the MPS1 MAP kinase (MAPK) cascade during conidiation and plant infection (PubMed:18344407).  Required for overcoming plant defense responses and the differentiation of secondary infectious hyphae in live plant cells (PubMed:18344407).
What are the official names of this protein?
MADS-box MEF2 type transcription factor MIG1.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URE2_ACTP2
Sequence: MIPGEYQLADGDIQANVGRKTVKLEVVNTGDRPIQVGSHYHFFETNHALKFDRLQARGMRLNVPSGNAVRFEPGEAKEVELVEFGGNKVIYGFHNEIDGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_BURVG
Sequence: MYAVIKTGGKQYKVAVGEKLKVEQIPADIDAEITLDQVLAVGEGESIKFGTPLVSGASVKATVVSHGRHAKVTIFKMRRRKHYQKHGGHRQNYTELRIDAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ISPG_PHOLL
Sequence: MHNESPIKRRKSTRIYVGNVPVGDGAPIAVQSMTNTRTTDVEATVKQIKSLERVGVDIVRVSIPTMDAAEAFKLIKQQANVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEARIREVVAAARDKNIPIRIGVNGGSLEKDIQEKYGEPTPEALLESAMRHVDILNRLNFDQFKISVKASDVFLAVGAYRLLAQEIEQPLHLGITEAGGARAGSVKSAIGLGILLSEGIGDTLRISLAADPVEEVKVGFDILKALRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDLLTPMDVSIIGCVVNGPGEAEVSTLGVTGARTKSGFYEDGIRQKVRLDNADMIDQLEAKIRAKASMLDENKRIGISQLDK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: AN13D_HUMAN
Sequence: MAGPGPTFPLHRLVWANRHRELEAALHSHQHDIEQEDPRGRTPLELAVSLGNLESVRVLLRHNANVGKENRQGWAVLQEAVSTGDPEMVQLVLQYRDYQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFKGQEAGALVMEVDHDRQVVHVETLGLTLQEPETLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKSRSKAGKTPFQSFLGMAQQHSSHTGAPVQQAASPTNPTAISPEEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPLSSVWVPAPSSAVAASGNPFPCEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAPGPPSFEEQLRLALELSSREQEERERRGQQEEEDLQRILQLSLTEH
What is the function of this protein?
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin.  Does not bind 'Lys-48'-linked ubiquitin.  Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 13D.
What are the subcellular locations of this protein?
Cell membrane. Late endosome. Note=Interaction with EGFR may enhance association with the cell membrane.
Protein: 3BHS_MYCTO
Sequence: MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKTAATVKP
What is the function of this protein?
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidation and isomerization of cholesterol, pregnenolone, and dehydroepiandrosterone (DHEA) into cholest-4-en-3-one, progesterone, and androsterone, respectively.
What are the official names of this protein?
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase, Cholesterol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_STRAG
Sequence: MAKDIKFSADARSAMVRGVDILADTVFVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLPQAIVREGLKNVTAGANPIGIRRGIETAVSAAVEELKEIAQPVSGKEAIAQVAAVSSRSEKVGEYISEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVSELENPYILITDKKISNIQEILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVVTEDLGLDLKDATMQVLGQSAKVTVDKDSTVIVEGAGDSSAIANRVAIIKSQMEATTSDFDREKLQERLAKLAGGVAVIKVGAATETELKEMKLRIEDALNATRAAVEEGIVSGGGTALVNVIEKVAALKLNGDEETGRNIVLRALEEPVRQIAYNAGYKGSVIIARLKQSEIGTGFNAANGEWVDMVTTGIIDPVKVTRSALQNAASVASLILTTEAVVANKPEPEAPTAPAMDPSMMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEU3_ONCKE
Sequence: MPYSTFPLLWVLGLLALSSACYIQNCPRGGKRSFPDLPRQCMSCGPGDRGRCFGPNICCGEGMGCYMGSPEAAGCVEENYLPSPCEAGGRVCGSEGSCAASGVCCDSESCVLDPDCLEDSKRQSPSEQNAALMGGLAGDLLRILHATSRGRPQ
What is the function of this protein?
Vasotocin is an antidiuretic hormone.
What are the official names of this protein?
Vasotocin-neurophysin VT 1.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CISD1_MOUSE
Sequence: MGLSSNSAVRVEWIAAVTFAAGTAALGYLAYKKFYAKENRTKAMVNLQIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHIKHNEETGDNVGPLIIKKKET
What is the function of this protein?
L-cysteine transaminase that catalyzes the reversible transfer of the amino group from L-cysteine to the alpha-keto acid 2-oxoglutarate to respectively form 2-oxo-3-sulfanylpropanoate and L-glutamate (By similarity).  The catalytic cycle occurs in the presence of pyridoxal 5'-phosphate (PLP) cofactor that facilitates transamination by initially forming an internal aldimine with the epsilon-amino group of active site Lys-55 residue on the enzyme (PLP-enzyme aldimine), subsequently displaced by formation of an external aldimine with the substrate amino group (PLP-L-cysteine aldimine).  The external aldimine is further deprotonated to form a carbanion intermediate, which in the presence of 2-oxoglutarate regenerates PLP yielding final products 2-oxo-3-sulfanylpropanoate and L-glutamate.  The proton transfer in carbanion intermediate is suggested to be controlled by the active site lysine residue, whereas PLP stabilizes carbanion structure through electron delocalization, also known as the electron sink effect (By similarity).  Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (PubMed:17376863).  May be involved in iron-sulfur cluster shuttling and/or in redox reactions.  Can transfer the [2Fe-2S] cluster to an apo-acceptor protein only when in the oxidation state, likely serving as a redox sensor that regulates mitochondrial iron-sulfur cluster assembly and iron trafficking upon oxidative stress (By similarity).
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 1, Cysteine transaminase CISD1, MitoNEET.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type III membrane protein.
Protein: CLPX_XANCB
Sequence: MSEDRQGRSGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQSARSSLPKPREILEVLDQYVIGQLRAKRTLAVAVYNHYKRIESRSKNDEVELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTKNILFICGGAFAGLDKVIQARSNDAGGIGFGAKVKSSERKQEVGKILAEVEPEDLIKFGLIPEFVGRLPVVATLEELDEPALIKILTEPKNAITKQFKKLFEMESVELEFRPDALSAIAKKALKRKTGARGLRTIVESVLLDTMYELPSQENVSKVVVDESVIEHKSEPYLIYQAQPAPAKAASGD
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RS14_MARMM
Sequence: MAKTSAIERNLKRARLAKRYAAKREQLKAIARNQELPVEERFAAQLKLAELPRNSAVTRIRNRCEITGRPRAFYRKFRMSRIAMRDYASQGMIPGMVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: Y909_MYCBO
Sequence: MDRTRIVRRWRRNMDVADDAEYVEMLATLSEGSVRRNFNPYTDIDWESPEFAVTDNDPRWILPATDPLGRHPWYQAQSRERQIEIGMWRQANVAKVGLHFESILIRGLMNYTFWMPNGSPEYRYCLHESVEECNHTMMFQEMVNRVGADVPGLPRRLRWVSPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKNVLREGKSLHPIMERVMSIHVAEEARHISFAHEYLRKRLPRLTRMQRFWISLYFPLTMRSLCNAIVVPPKAFWEEFDIPREVKKELFFGSPESRKWLCDMFADARMLAHDTGLMNPIARLVWRLCKIDGKPSRYRSEPQRQHLAAAPAA
What are the official names of this protein?
Uncharacterized protein Mb0909.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VG424_BPPF1
Sequence: MSIKIHHGPNGSYKTSGAIQDDAVPALKDGRVIITNVRGFTLERAYQVFPDLPNTAEIINLDLESLEDLEKMRTWFQWAPRGAFLIFDETQLLFPKSWREKDLERFDYPGGPEAAHAADRPMGWLDAWTRHRHFNWDIVLTTPNISYIRDDIRMTCEMAYKHSNLAVIGIPGRYKEAQHDAQLNRPPADGTIIEYKRIRKQTFALYQSTATGKTQDTKAGKSLFRSPKLVLLLALLAGTIGFVWYMGPLRTIGGPAAATPADAPGDPAQAPAAPAAVAAPARPAANSFLPPGLVPDGPAAAPVDLNAHPFADRRISILAHAYRKSRGDIYMFALEDPTGRHLELTSWQLIGSGYRVTPKGECVVELRYEDWKQTVTCAGRQAGAVASIAPAAPVAASADAPARGQSPLTIVPDSEYASRPWRQK
What is the function of this protein?
May play a role in phage assembly.
What are the official names of this protein?
Uncharacterized protein ORF424, ORF 424.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: ARGB_BACVZ
Sequence: MKKTIVFKCGGSVIRELSADFFQNVKELMQSGWNIAVVHGGGPDISKMLKTLQIETEFVDGQRKTTKPVLETAEMVLSGTINKFFVTELAKNGLKAAGISGKDGGLLQASYLNQDKYGEVGEIQKTDPSIIHALMKEGIIPVIAPLSMTSDFETLNVNADAAASAVASALHADKLLFVTDVEGIMDGESRLDTLTPQEIQALIDDGVISGGMIPKVNSALSALSEDVEEVMIVNGKGAFFTDQAFQGTKIVKEKESVS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP4_ROTHJ
Sequence: MASLIYRQLLSNSYVTNISDEVNEIGTKKTTNVTVNPGPFAQTGYAPVDWGHGELPDSTLVQPTLDGPYQPTSLNLPVDYWMLIAPTREGKVAEGTNTTDRWFACVLVEPNVQNTQRQYVLDGQNVQLHVSNDSSTSWKFILFIKLTPYGTYTQYSTLSTPHKLCAWMKRDNRVYWYQGATPNASESYYLTINNDNSNVSSDAEFYLIPQSQTAMCTQYINNGLPPIQNTRNIVPVNITSRQIKDVRAQMNEDIVISKTSLWKEMQYNRDIIIRFKFANSIIKSGGLGYKWSEISFKPMNYQYTYTRDEEEVTAHTTCSVNGVNDFNYNGGTLPTDFAISRFEVIKENSYVYVDYWDDSQAFRNMVYVRSLAANLNDVVCSGGSYSFALPVGNHPVMSGGAVTLTSAGVTLSTQYTDYVSLNSLQFRFRLAVSEPSFSISRTRMSGIYGLPAVNPNNSAEYYEIAGRFSLISLVPTNDDYQTPIANSVTVRQDLERQLGELREEFNSLSQEIAVSQLIDLATLPLDMFSMFSGIKSTVEAVKSMTTNVMKRFKTSSLANAISDLTSNMSEAASSVRLTSVRSVGTITLPRARVSLQVGDDLRSMQDVSTQVSNVSRNLRLKEFTTQTDTLSFDDISAAVLKTKLDKSTQISQQTMPDIIAESSEKFIPKRSYRIVDEDIRFETGIDGTFYAYKVDTFNEIPFDMERFNKLITDSPVLSAIIDFKTLKNLNDNYGITKKQAMELLHSNPKTLKEFINNNNPIIRNRIENLISQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: Y2488_PHOLL
Sequence: MDLDLNNRMTEDETLEKAYDIFLELASFNLDPADILLFSLQFEIRGGAELLPPSDGWLKHVDFNPNPDFFAEVIIGLAESEDAEINDVFARILICREKSHPIYHILWKE
What are the official names of this protein?
UPF0263 protein plu2488.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: SECF_RICCN
Sequence: MQIYPLRLLPNKIDFDFMNFKKVSYTFSIILSLISFIWIGIYKFNFGIDFAGGIVIEVRLDQAPDLPKMRGVLGKLGIGEVVLQNFGSERDLSIRFGSSSEENLMKNIELIKGFLQSNFPYKFEYRKVDFVGPQVGRQLIEAGAMAMLFSFLAIMVYIWVRFEWYFGLGILIALVHDVILALGFMSMTKLDFNLSTIAAVLTIIGYSVNDSVVIYDRIRENLRKYHKKNITEIINLSINETLSRTILTVITTLLANLALILFGGEAIRSFSVLVFFGIIAGTYSSIFISAPILTMFVNRKFNKKVIER
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLNA2_MEDSA
Sequence: MAQILAPSIQCQTRITKTSPLATPISSKMWSSLVMKQNKKVARSAKFRVMAINSGTINRVEDLLNLDITPFTDSIIAEYIWIGGTGIDVRSKSRTISKPVEHPSELPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRGGNNILVICDAYTPQGEPIPTNKRHKAAEIFSNPKVEAEIPWYGIEQEYTLLQTDVKWPLGWPVGGYPGPQGPYYCAAGADKSFGRDISDAHYKACLYAGINISGTNGEVMPGQWEYQVGPSVGIEAGDHIWASRYILERITEQAGVVLTLDPKPIEGDWNGAGCHTNYSTKSMREDGGFEVIKKAILNLSLRHKVHIEAYGEGNERRLTGKHETASINTFSWGVANRGCSIRVGRDTEKNGKGYLEDRRPASNMDPYVVTALLAESTLLWEPTLEAEALAAQKIALKV
What is the function of this protein?
The light-modulated chloroplast enzyme, encoded by a nuclear gene and expressed primarily in leaves, is responsible for the reassimilation of the ammonia generated by photorespiration.
What are the official names of this protein?
Glutamine synthetase leaf isozyme, chloroplastic, GS2, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL5_SHEB9
Sequence: MAKLHDKYQETVVAELAKKFGYTSVMQVPRIEKITLNMGVGEAVADKKIMDHAVRDMTAIAGQKPVVTVARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSAKAFDGRGNYAMGVREQIIFPEIDYDKIDKIRGMDIVITTTAKNDEEGRALLDAFNFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: EQXF_FUSHE
Sequence: MADQVQDVHPMEWGPGKTPQGRARLPSSFDATVKDPVAAVHSENLVCRVPMHRIRHLESLVYDLMQNSSANVNQEQVGVTPSPGDQPHVPDYPTPSAAHAPSTNQEPASAAVSPADYGSMQSTGGGANYVGSAHWAAVLDGIAELKDHLDNEESHHSDSQGVDPPCLQVTGPQLLYGCPKPADKDEILSSIPARSVVDRLVSRYFNSFEMSPAVLHSVQFLKEYEEFWEDPQTTSPIWLGLLFTIMCLATQFEKSRLDPGVQSPAVLSMERELQEMVDTFRLRIPQCLVLGSYAKGGPFVLETLMLYIAAEIFLSNDAEIEIWILMGNTVQLALHMGYHRDPKHFKGLSPFTAEMRRRIWATIVEMDLGLSAQMGLPRMIKHWQTDTQEPSNFQDSDFDSATVEMPPSRLNTDLTPILYRLVKARLMTTIGYIWDFSADVRPYPYTEVQKMDDKLDQARKSIPECLKWHSMARNITDSPQHIMQKVILETVFYRAKIVLHRKYMFLPLAQSASSRRIVLESALKLLDYQHMLQEETQPFCQLYQERWRVSSLVNHDFLLATSILCYYLQHARGATPQLSESASFDETIMTSLSRSHDIWLQSSNSSKEARKVVRALAVILGRVNTPSADAAGESGLVFGLQSTYPPSTTNDYSQAPMITPTAEWQEMDGQSQWLPGPRVIQRLTYDMQRQQMRWGL
What is the function of this protein?
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of Equisetin (PubMed:23614392).
What are the official names of this protein?
Equisetin cluster transcription factor eqxF, Equisetin biosynthesis protein F.
What are the subcellular locations of this protein?
Nucleus.