PharMolix/UniProtQA huggingface dataset:
Protein: RFT1_XENTR
Sequence: MGSQEVLMDATKLASYSVILQILFRVLTFALNAFTLRYVSKEIIGIVNVRLTLFYTTVVFLAREAFRRACLSHSAQQSWRHTIHLTWLAVPLGICWSFILGWIWLQILEVPEPEAIPYYNIGVWAFGFSAVVELLAEPFWVLAQAHLFVKLKVVAESLAIIIRCSVTVILVLLCPQWGLLIFSLAQVLYTSALALCYIAYFARFLGSLEAEKKPFPLRRMREFLPRFSSSQAFLDWKQAWLAWSFFKQSFLKQILTEGERYVMTFLNVLSFGDQGVYDIVNNLGSLVARFIFLPIEESFYVFFAKVLERGKKVQSQRKEEISMASEVLESLLKLVTLIGLVIIAFGYAYSHLALDIYGGSMLSGGSGPVLLRCYCLYVLLLAINGVTECFTFASMGKEDVDRYNYVMLGLSLSFLCLSYYMTLWLGSVGFILANCFNMGLRITHSLLYIMRYYKGSPYQPLIGLLPSPVVVCVLAVSAAVTGYSEVALCCDKGWLLCLGHIVVGGLCLLVTLGAAVLSEKKLTHFIRSHLLSRHQRKEQ
What is the function of this protein?
May be involved in N-linked oligosaccharide assembly.  May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane (By similarity).
What are the official names of this protein?
Protein RFT1 homolog.
What is the protein family that this protein belongs to?
Belongs to the RFT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NAA80_HUMAN
Sequence: MELILSTSPAELTLDPACQPKLPLDSTCQPEMTFNPGPTELTLDPEHQPEETPAPSLAELTLEPVHRRPELLDACADLINDQWPRSRTSRLHSLGQSSDAFPLCLMLLSPHPTLEAAPVVVGHARLSRVLNQPQSLLVETVVVARALRGRGFGRRLMEGLEVFARARGFRKLHLTTHDQVHFYTHLGYQLGEPVQGLVFTSRRLPATLLNAFPTAPSPRPPRKAPNLTAQAAPRGPKGPPLPPPPPLPECLTISPPVPSGPPSKSLLETQYQNVRGRPIFWMEKDI
What is the function of this protein?
N-alpha-acetyltransferase that specifically mediates the acetylation of the acidic amino terminus of processed forms of beta- and gamma-actin (ACTB and ACTG, respectively) (PubMed:30028079, PubMed:29581253).  N-terminal acetylation of processed beta- and gamma-actin regulates actin filament depolymerization and elongation (PubMed:29581253).  In vivo, preferentially displays N-terminal acetyltransferase activity towards acid N-terminal sequences starting with Asp-Asp-Asp and Glu-Glu-Glu (PubMed:30028079, PubMed:29581253).  In vitro, shows high activity towards Met-Asp-Glu-Leu and Met-Asp-Asp-Asp (PubMed:10644992, PubMed:29581307).  May act as a tumor suppressor (PubMed:10644992).
What are the official names of this protein?
N-alpha-acetyltransferase 80, HsNAAA80, N-acetyltransferase 6, Protein fusion-2, Protein fus-2.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: HYES_HUMAN
Sequence: MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM
What is the function of this protein?
Bifunctional enzyme (PubMed:12574510).  The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy-octadec-9E-enoic acid (PubMed:12574510).  Has phosphatase activity toward lyso-glycerophospholipids with also some lower activity toward lysolipids of sphingolipid and isoprenoid phosphates (PubMed:22217705, PubMed:22387545).
What are the official names of this protein?
Bifunctional epoxide hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome.
Protein: RUVC_BIFLO
Sequence: MIILGVDPGLTRCGVGVIEAGEHRRLSFIHVDVVRSSPDITQDLRLLAIYNGLSEKMDRFAPDAVSIERVFAQSNRNTVLGTAQAAGLAMLAAAQRNIPVALHTPTEAKLAITGNGQAQKIQVERMVTRILNLTKMPTPADAADALALAICHALRPAGALQGGEREQHLTAAQRQWAEAAQNSTRRRINHDRGM
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: GRPE_MYCPN
Sequence: MSENSLTITEILSSIRTLLVKHNKAKVTQIEKELLQAVAELEKKFKQQVQNFNELQQKIPNLQKVNEEFRLKVEKIQEEAQKKIQEKVAELTIKSKEELENAKKYVIEKSIDQPLIIIDQFEIALSYAQKDPQVKNYTTGFNMVLDAFSRWLEGFGVTKIAIEPGAQFDEKVMAALEVVPSDQPANTVVKVSKSGYKLHDKVIRFASVVVSQGNKTE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDA_ECOL6
Sequence: MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: GLYA_BIFAA
Sequence: MTASPLAQTPNDMFNAPIAEADPEIAEILDAELSRQQNGLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGGCEQVDKIETIARERAKSLFGAEYANVQPHSGAQANAAVYQALVKPGDTVLGLALDHGGHLTHGMKINFSGRFYHAEAYGVNPETFRIDPEIIRQRALETHPAMIIGGWSAYPRIEDFKAMKEIADEVGAKFWVDMAHFAGLVAAGLHPSPVPYADVVSSTAHKTLGGPRSGFILAKQEYAKKLNSAVFPGQQGGPLMHVIAGKAVAFKVAATPEFKDRMQRTLDGAKILAERLMADDVKNNGISVLTGGTDVHLVMVDLRNSEMDGKQGEDLLAQCGITINRNTVPFDPRPASVASGLRIGTSALATRGFGPKEYEEVADIIGTALAAGQDVDALKARVDKLAEDFPLYPGLDQIH
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_STAHJ
Sequence: MTKPIVAIVGRPNVGKSTIFNRVVGERVSIVEDTPGVTRDRIYSSGEWLTHEFNIIDTGGIEIGDAPFQTQIRAQAEIAIDEADVIIFMVNVREGLTQSDEMVAQMLYKSKKPVVLAVNKVDNPEMRNDIFDFYSLGFGDPYPISGSHGLGLGDLLDEVVKHFDEETEDSYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAVDTEYSYDGQDYVLIDTAGMRKKGKVYESTEKYSVLRALKAIERSNVVLIVIDAEEGIIEQDKRVAGYAHEEGKAVVIVVNKWDTVDKDSNTMKKFADDVRNQFQFLDYAQIAFVSAKEGTRLRTLFPYINEASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYTTQVANEPPTFVVFVNDVELMHFSYKRYLENQIRHAFGFEGTPIHIIPRRRN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: BETA_BURPS
Sequence: MTTREFDYIICGAGSAGNVLATRLTEDPGVTVLLLEAGGPDYRFDFRTQMPAALAYPLQGRRYNWAYETDPEPHMNHRRMECGRGKGLGGSSLINGMCYIRGNALDYDNWATHKALEDWAYLDCLPYFRKAETRDVGPNDYHGGDGPVSVTTSKPGVNPLFEAMVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPRGRRASTARGYLDQARARPNLEIVTHALADRILFSGKRATGVTFLHGSARVTAHARREVLVCSGAIASPQLLQRSGVGPGEWLRELDIPVVLDLPGVGRNLQDHLEMYIQFECKEPVSLYPALKWWNQPKIGLEWMLNGTGLGASNHFEAGGFIRTRDDDPWPNIQYHFLPVAINYNGSNAIEMHGFQAHVGSMRSPSRGRVKLKSRDPHAHPSILFNYMAEALDWREFRDAIRATREIMRQPALDRFRGRELNPGADLKSDNELDTFVRARAETAFHPSCSCKMGYDDMAVVDNEGRVHGIDGLRVVDASIMPIITTGNLNAPTIMIAEKIADRIRQHKPLERSNAQYYVANGAPARGGKPARAPAVV
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: KEX1_PHANO
Sequence: MLLTHTSSRWRTAAVCALAATASWLPSVQAAEKTQADYFVSSLPGAPEGPLLKMHAGHIEVDAEHNSNLFFWHYENRHIADRQRTVLWLNGGPGCSSMDGAMMEIGPYRVKHGGHLEYNNGSWDEFANMLFIDQPVGTGFSYVNTDSYLTDLDQMAEHMMIFLEKWFKLFPEYENDDLYIAGESYAGQHIPYIARAILNRNKNQNTDPKPWNLKGLLIGNGWISPADQYLAYLPFAYQNGMIQADSDSAKRVEQQQSICIQKLQDGGHDKVDTSECEQIMVAILEETKDRKADRMNQCLNMYDIRLRDDSSCGMNWPPDLTDVTPYLRRPDVIKALHINSDKKTGWSECNGAVSGHFRAKNSVPTVKFLPELLTEVPILLFSGDKDFICNHVGTEAMIENMSWNGGKGWEVSPGVWAPKQDWTFEGEPAGTYQEVRNLTYVVFYNSSHMVPFDYPKRTRDMLDRFMNVDISAIGGDPADSRIDGEKGPLTSVGDHPNSTKAEEDKAQQLKEAEWKAYYRSGEVVLVILIIVACLWGAFLWRTRRSTSLYKGVDGDEGRESLLTGMGLDNFRRGARRHDVEAADFDERELDDLDDAPKKPANGYSNVNSEKERQPHNDSTFSLGADSDDEAEGSERGRRKEHS
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: RL29_SALEP
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ERII_HERER
Sequence: MSLHLSQDFALKASAAVAVLLLAAWVRLRRRIQSKISNIPGPKPTSLLGNYSQLHSAEKGWEFFDEIHAKYGNVCRISTPVGCNDIIYLADPLALNHMNRRDEAKFDDPHEIHIMLQMVLGNKGLGATSGAEHHRQRKFLNPVFGPSYLRHMPPLFYEVTHRFLDAMRILCADGQREIDMSHWGTRVSLEFVGKGAIGFELDSLAIDSKPNLYGEEMKQGFVALSTPAARLAMKYFLPRIASLRTPKFNRWLLNLVPSPLVTIVKNFVWELDANSRTMFQQKKEALLKGGDALSEQSSKGKDLMTALIREHVLVDRADKVDEEEATSHFRTLLFAATDTSSSAILRTIQLLAEHPDVQTRLREEINTAKADADGDLSYEKLLALPLLDAVYRETLRLYPPASYIDRVAHEDVVLPLAFPITGVDGTQMSELVVPKGTVVTMSIVGVNRSTAIWGPDALVWNPDRWLAPLPETVKSSKMPGITSSIMTFLDGKRHCLGYRYVQMELKILISEIVCTLAFAPTEKHAKIEWPMGLTLSPFVDGKMSMPLKVSLA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of erinacines, cyathane-xylosides that show unique biological activities, including leishmanicidal activity, stimulating activity for nerve growth-factor synthesis, and agonistic activity toward the kappa opioid receptor (PubMed:31535864).  The geranylgeranyl diphosphate (GGPP) synthase eriE catalyzes the first step in erinacines biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:31535864).  GGPP is then substrate of the diterpene cyclase eriG for the production of cyatha-3,12-diene (PubMed:28371074).  EriG is unable to use geranyl diphosphate (GPP) or farnesyl diphosphate (FPP) as substrates (PubMed:28371074).  The cytochrome P450 monooxygenase eriI then hydroxylates cyatha-3,12-diene at C-14 of the seven-membered ring to produce erinacol, which is further hydroxylated at C-15 by the cytochrome P450 monooxygenase eriC to yield cyathadiol (PubMed:31535864).  The cytochrome P450 monooxygenase eriA then catalyzes C-11 hydroxylation in the presence of the short chain dehydrogenase/reductase (SDR) eriH, which leads to the production of cyathatriol (PubMed:31535864).  The acetyltransferase eriL converts cyathatriol into 11-O-acetyl-cyathatriol (PubMed:31535864).  The SDR eriH catalyzes further oxidation of 11-O-acetyl-cyathatriol into 1-O-acetylcyathin A3 (PubMed:31535864).  Finally, the glycosyl transferase eriJ tranfers xylose from UDP-xylose onto C-14 of 11-O-acetyl-cyathatriol to form eracine Q (PubMed:31535864).  EriJ is also able to convert 11-O-acetyl-cyathatriol to eracine Q2 by using UDP-D-glucose as cosubstrate, but at a lower rate (PubMed:31535864).  In the absence of eriL and eriJ, the SDR eriH is able to convert cyathatriol to cyathin A3; this is likely a switching mechanism in the biosynthesis of cyathins (C-14 ketogroup)and erinacines (C-14 glycosylated group) (PubMed:31535864).  The roles of the SDR eriB, the polyprenyl transferase eriF and the dehydrogenase eriK have still to be identified (Probable).
What are the official names of this protein?
Cytochrome P450 monooxyhenase eriI, Erinacine biosynthesis cluster protein IA.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SPEH_METVS
Sequence: MKQLGKHIILELWGCEKQALDDQPGVEKMLVNAVKACGATLICVKTHKFSPQGVTGVAVLAESHISIHTWPELGYAAMDVFTCGEHVIPEDTIPEIRNFLKPDKVEVIDIKRGIVDIEEVLA
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: FUMC_METAC
Sequence: MPSILDLPIGTGATGKRKESDSLGEVEVPADHYWGAQTQRSLIHFSIGDDYMPKEVYHAYGYVKKAAALVNEAAGIIPPWKAELIARVADEVIAGKLDSEFPLYVWQTGSGTQSNMNVNEVISNRAIQLVGGSLGSKHPVHPNDDVNMSQSSNDTFPTAMHIATVLEFSNRLIPAVTVLEESIWAKAREWVDIVKIGRTHLQDATPLTVGQEWSGYATQLDDALAFVKHSLRGLYRLAIGGTAVGTGINTPPDFGEKVADEIARLTGHPFVTAPNKFAAQGSLDAMVTSSAALRTLAVALMKIANDLQWLGSGPRSGLHELILPSDEPGSSIMPGKVNPTQEEAMLMVCIQVIGEDNAVAFAGSQGNFELNAMCPIIINNVLHSARTLGDACVKFREYGINGIMLDRSRIDKFVGTSLMLVTALSPVIGYDKASAIVQRALDENTTLREAAVKGGFISAEDFDRIVDPKKMVGDPRHDLKLASE
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGE_BRUME
Sequence: MSLYGMMRTGVSGMNAQANRLSTVADNIANASTVGYKRAETQFSSLVLPSTAGQYNSGSVLTDVRYGISDQGGIRSTSSTTDLAIDGNGYFVVQGPGGSTYLTRAGSFVPDKNGDLVNSAGYYLLGAGADEAAGGLTVAGLNIVNVNAAALPAEGSTAGDFTVNLPSTDQAPAAGGYNHKTSLISYNDKGEKITLDVYFTKTGADEWNVSVKNAADGVEIGTTVLNFDPTTGDLVSGGNVAVNLGAYGGQTLNLNLGGSTQRAGDYTISQAVINGQAPSSIKGVDVGNDGAVVAVYENGTQKVLYRIPLANVASPDRMTVVSGNIFLPSAESGDVRLGFPQGDGMGKIMSGTLEESNADIAQELTDMIEAQRSYTANSKVFQTGFELMDVLVNLKR
What is the function of this protein?
The flagellum is required to cause a persistent disease in a murine model of infection.
What are the official names of this protein?
Flagellar hook protein FlgE.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: CAB45_CAPHI
Sequence: MASRQGPLCGLAPCCLWLLGVILLMNASARPANHSSARERAGNREENEILPPDHLNGVKLEMDGHLNKDFHQEVFLGKDMDDFEEDAEPRKSRRKLMVIFSKVDLNTDRRISAKEMQKWIMQKTAEHFQEAVAESRAHFRAVDPDGDGHVSWDEYKVKFLATKGHNEREVAEKIKNKWDLNIDEETQEVLENLKDRWYQADNPPPDLLLTESEFLSFLHPEHSRGMLQFMVKEIIRDLDQDGDKKLSLSEFISLPVGTVENQQGQDVDDGWVRDRKREFEELIDANHDGIVTMAELEDYMDPMNEFSALNEAKQMIAIADENQNHYLEPEEVLKYSEFFTGSKLVDYARSVHEEF
What is the function of this protein?
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
What are the official names of this protein?
45 kDa calcium-binding protein, Cab45, Stromal cell-derived factor 4, SDF-4.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Golgi apparatus lumen.
Protein: RIMO_CHLPB
Sequence: MPENSPETMTRNRSIFLLSLGCSKNTVDSERLIGQARRKGLSFTNEPDEADIVIINTCGFIADAKTESIDEILAAAEKRKNGEIEALYVMGCLSALYAAELRAELPEVDRFFGTADLPEILNILGTAYDPATRFERSLLSPSHYAWLKLSEGCSRTCSFCAIPKMRGRYKSESMEDLLQEATRLKAKGVKELNLIAQDITPYGLDLYGTSRLNDLMRELSDLNFDWIRLLYAYPLDFPLEVIDTMRERENICDYLDMPVQHICDRILASMKRGIDKQGTIGLLESIRKRNPNIRLRTTMIVGYPGETRAEFEELLQFVREFRFDRLGCFPYSHEEHTAAYDNLEDDIPEEEKQERVGELMELQEGISEKKNRALEEKALKVLVEEVEDNLAFARTEYDAPEVDNECVLDTAGIDIRPGDFCMATIEESSAYELVGRIKNVIP
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_MYCUA
Sequence: MLIPRKVKHRKQHHPRQRGIASGGTSVNFGDYGIQALEHAYVTNRQIESARIAINRHIKRGGKVWINIFPDRPLTKKPAETRMGSGKGSPEWWVANVKPGRVLFELSYPNEAIARAALTRAIHKLPIKARIITREEQF
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: P2XE_DICDI
Sequence: MNFRNIDWDSLFSYSTIKIVRIRDKRLGILHFAFLIGIILYIIVGTIFLQKKYLVLESPIGSIRTSLMAPSVKPTDLPYCLKNGTDTSYDGYPNKPCQYWDEYLVLYPPSEESSMFITTRCTQETQSTVNGCNLSEPTCVYNTTSSSDFYIANVENFTILLDHTLSAPSLGIQYNGAQLNGQLLDTDGNPMSLPPPNIVGVKGSPDIMSLQGVLTAAGVESLDSQGLANKSRTIRDDGILILCFITYSNTYTYNTGNYHYTYQFKLVQNTKYKIVEPVFTKDVEDRYIFDRHGVRIIFIQTGQLGQFDFQTMLLTFVSGIGLVTAASLIVDIIATRIMPQRSRYQELKFQDSSINNTQKTPTNDHTPLLKDNEDTINENSYQNNSYEK
What is the function of this protein?
P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling.  Not required for the purinergic response to extracellular nucleotides.  Not essential for osmoregulation.  Inward currents evoked by intracellular ATP.  ATP analog beta, gamma-imido-ATP is a weak partial agonist of p2xE.  Exclusively selective for ATP over other nucleotides.  Insensitive to copper and P2 receptor antagonists PPADS and suramin but strongly inhibited by sodium ions.  More permeable to ammonium than either sodium or potassium ions and less permeable to choline.  Permeable to calcium ions, but not chloride.
What are the official names of this protein?
P2X receptor E, P2XE.
What is the protein family that this protein belongs to?
Belongs to the P2X receptor family.
Protein: YCF4_ORYSA
Sequence: MNWRSEHIWIELLKGSRKRGNFFWACILFLGSLGFLAVGASSYLGKNIISVLPSQQILFFPQGVVMSFYGIAGLFISAYLWCTILWNVGSGYDRFDRKEGVVCIFRWGFPGIKRRVFLRFLMRDIQSIRIQVKEGLFPRRILYMEIRGQGAIPLTRTDEKFFTPREIEQKAAELAYFLRIPMEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RHAM_RHIME
Sequence: MEKYAFRMRLHPGKAAEYQARHDAIWPELVTLLKDAGVSDYSIHLDEENCLLFGVLWRSDDHRMGDLPSHPVMRKWWAHMADIMETRADNEPVAVPLKTVFHLK
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHH_DANAP
Sequence: VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.
What are the official names of this protein?
Indian hedgehog protein, IHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Cell membrane. Secreted, extracellular space. Note=Indian hedgehog protein N- product: Cell membrane; Lipid-anchor; Extracellular side. The N- terminal peptide remains associated with the cell surface. Indian hedgehog protein C-product: Secreted, extracellular space. The C- terminal peptide diffuses from the cell.
Protein: MUTS_BRASO
Sequence: MASFRAMTIQQPISVPVPQEATPAEAPAKLTPMMEQYLDIKAAHPGLMLFYRMGDFYELFFEDAEVASKALGIVLTKRGKHQGQDIPMCGVPVERSEDYLHRLIAQGIRVAVCEQMEDPAAARARGNKSVVKRGVVRVVTPGTLTEDNLLDARANNYLLSIARSRGSSGGDRLGLAWIDISTSDFIVTECAFAELTATLARINPNEVIVSDALYSDEAFEPVLRELAAVTPLTRDVFDGATAERRLCDYFAVATMDGLAVLSRLEATAAAACVTYVERTQVGQRPPLAPPAREATGSTMAIDPATRANLELTRTLAGERRGSLLDAIDCTVTSAGSRLLAQRLAAPLTEPAQIGRRLDAVNAFVADSAAREDIRVILRGAPDMTRAMARLSVGRGGPRDLAALRDGILAADQALARLSVLDQPPQEIASVMAALARPARALADEFARALDEQLPLIKRDGGFVRSGYDATLDETRNLRDASRLVVASMQARYADQTGVKALKIRHNNVLGYFVEVTAQHGDKLMSAPLNATFIHRQTLAGQVRFTTSELGEIEAKIANAGERALNLELEIFDRLCAQALAIGDDLRAAAHGFAMLDVATALAKLALDDNYVRPEVDGSLGFAIEGGRHPVVEQSLKREGQPFIANSCDLSPTPGHKSGQLWLLTGPNMAGKSTFLRQNALIALLAQIGSFVPASRARIGIVDRLFSRVGAADDLARGRSTFMVEMVETAAILNQAGERALVILDEIGRGTATFDGLSIAWAAIEHLHESNRCRTLFATHYHELTALAAKLPRLFNATVRVKEWQGDVVFLHEVLPGSADRSYGIQVAKLAGLPPAVISRAKSVLAKLEAADRGQNARALVDDLPLFAVPSRAAVEPAMSKETEELIAAVKDLHPDEMTPREALDALYRLKAKLPAK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: Y1981_BACC1
Sequence: MKNILFRINELSKKEKVSGLTVDEKQEQQMLRQNYTQTFRGSLDSILLNTKIVDQNGHNVTPAALQDAQIRLKLSK
What are the official names of this protein?
UPF0291 protein BCE_1981.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.