PharMolix/UniProtQA huggingface dataset:
Protein: MAO1_ECOSM
Sequence: MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRITDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEETARQKVFMVDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLVLPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: CAIT_SALDC
Sequence: MKNEKKKSGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGDEKPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKEIGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMDVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMHLPRMLFYTDAIGKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVMGLTASTWILWTVLGSNTLLLMDKNILNIPQLIEQHGVARAIIETWAALPLSTATMWGFFILCFIATVTLINACSYTLAMSTCREVRDGEEPPLLVRIGWSVLVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKVHWKDK
What is the function of this protein?
Catalyzes the exchange of L-carnitine for gamma-butyrobetaine.
What are the official names of this protein?
L-carnitine/gamma-butyrobetaine antiporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HMUV_BRADU
Sequence: MSAVIEARHLSKRAGRAKLLDGVGLTVAAGEMVAIIGPNGAGKSTLLRLLSGDLRPSQGEVWLKQRDIGSYTPRELAARRAMLSQHINVTFPFTVEEIVLMGAGDRSAREAGRLVDAALDEVGLAHFRERQLPTLSGGEQQRAHFARVLVQLACGEAEHGPGLLLLDEPTSSLDLRHQIDLVEAARRRAGTGTAVIAILHDLNLAIRFADRLVVLSGGKLAADGPRTEVVTRETIRDIFEIDAVVHQADGVPYVLPQSMRAAASAARI
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: F16PA_CELJU
Sequence: MQRLVPTLRRDGVNPELIPVIRTLLAATKEIAFRVRQGALSGVLGSTLDENIQGETQKQLDVIANQLIKDLLLEEPQVRAIASEEEDTVVAGNPKGAYTVAFDPLDGSSNIDINGQIGTIFTIYPARDDVPADSEAQFQQPGHQQVCAGYVLYGPSTILVMTTGGPTRGYTLDATHGSYLLTQAQLSVPLNTQEFALNMANQRFWSAPFQRYVQDLLLGETGPRAKRFNMRWNAAMVGDVHRVLTRGGIFMYPSDNRNPRQPAKLRLLYEANPMAMLTENAGGKAWSENQRILNIQPDSLHQRVAVILGSANEVDVCMSYLLE
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_SHEHH
Sequence: MIVGLGTDIVEIARIEARIPTAGDEALLSCRLAKRVLTKTEFALFVASSQPGRYLAKRFAAKEAAAKALGTGIGRGVSFQHIEISNNTNGAPLVAFSDGAAERLAQLGGSRAHLSIADEKHYATATVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTC3_YEAST
Sequence: MMGRNGIRLALKRSFSTYQPPVVEITNITKLWPTLRPEVRDEIKEYLRWRMQEDWRHIPLEETKAAYFLSYGPCGGRSKGNEWNVGYTGMRIVFNLVLFGGAATAFYNWKQDKKLEEQLRDLV
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 3, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RIR2_EBVB9
Sequence: MSKLLYVRDHEGFACLTVETHRNRWFAAHIVLTKDCGCLKLLNERDLEFYKFLFTFLAMAEKLVNFNIDELVTSFESHDIDHYYTEQKAMENVHGETYANILNMLFDGDRAAMNAYAEAIMADEALQAKISWLRDKVAAAVTLPEKILVFLLIEGIFFISSFYSIALLRVRGLMPGICLANNYISRDELLHTRAASLLYNSMTAKADRPRATWIQELFRTAVEVETAFIEARGEGVTLVDVRAIKQFLEATADRILGDIGQAPLYGTPPPKDCPLTYMTSIKQTNFFEQESSDYTMLVVDDL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: RL361_SALPA
Sequence: MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CSP37_CANAX
Sequence: MSAGKYLLGTAALVGGVYYYDQYVQPILPRQQHQELAYQTQRVENKGSELNNKLTKKIEEGKKFVNEKTESVTKQVKNSDVYQKLQLNTEDYKKHVEDAVDNDKNVFVVGIQKYIDFVNQLGEVKVQTGTTQYSTVSPNVEVKEKSIFGNWFDKSDNKVDQLKNDADKKINEAKDKAESTKSDFFNWNSKKADELDKKANEAINWTNKQIDYASAEWHKHYEQAKGDWNKALDDLSKQWNDSKKQLNGRFDTEKDRAIKGVEDAKSNFEKLSNDLANDASKNQKLKDAQDHFGKSLENLKLFGDDVYNDFAKRFDDLFNRK
What are the official names of this protein?
37 kDa cell surface protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RS19_ACISJ
Sequence: MTRSLKKGPFVDHHLVAKVEKAIATKDKKPVKTWSRRSMVLPEFIGLTIAVHNGKQHVPVYVTDQMVGHKLGEFALTRTFKGHPADKKVQKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: YQGF_ACTP2
Sequence: MARTILAFDFGTYSIGCAVGQDITGTAQGLPSFKAQDGIPNWDQIEKVIKEWQPERLVVGLPLNMDGSEQPLTQRAKKFANRLNGRFNLPVELQDERLTTVSAKAEIFERGGYKALKKDKVDSISACLILESWFEAQ
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSAV_SALDC
Sequence: MRSWLGEGVRAQQWLSVCAGRQDMVLATVLLIAIVMMLLPLPTWMVDILITINLMFSVILLLIAIYLSDPLDLSVFPSLLLITTLYRLSLTISTSRLVLLQHNAGNIVDAFGKFVVGGNLTVGLVVFTIITIVQFIVITKGIERVAEVSARFSLDGMPGKQMSIDGDLRAGVIDADHARTLRQHVQQESRFLGAMDGAMKFVKGDTIAGIIVVLVNIIGGIIIAIVQYDMSMSEAVHTYSVLSIGDGLCGQIPSLLISLSAGIIVTRVPGEKRQNLATELSSQIARQPQSLILTAVVLMLLALIPGFPFITLAFFSALLALPIILIRRKKSVVSANGVEAPEKDSMVPGACPLILRLSPTLHSADLIRDIDAMRWFLFEDTGVPLPEVNIEVLPEPTEKLTVLLYQEPVFSLSIPAQADYLLIGADASVVGDSQTLPNGMGQICWLTKDMAHKAQGFGLDVFAGSQRISALLKCVLLRHMGEFIGVQETRYLMNAMEKNYSELVKELQRQLPINKIAETLQRLVSERVSIRDLRLIFGTLIDWAPREKDVLMLTEYVRIALRRHILRRLNPEGKPLPILRIGEGIENLVRESIRQTAMGTYTALSSRHKTQILQLIEQALKQSAKLFIVTSVDTRRFLRKITEATLFDVPILSWQELGEESLIQVVESIDLSEEELADNEE
What is the function of this protein?
Component of Salmonella pathogenicity island 2 (SPI-2) type III secretion system, required for secretion of some type III-secreted effectors including the SpvB exotoxin.
What are the official names of this protein?
Secretion system apparatus protein SsaV.
What is the protein family that this protein belongs to?
Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEMA_I68A0
Sequence: MKTIIALSYIFCLALGQDLPGNDNSTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGIHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEEMGNGCFKIYHKCDNACIESIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RNH_PSESM
Sequence: MSDSVELFTDGACKGNPGPGGWGALLVCKGVEKELWGGEANTTNNRMELTGAIRGLEELKRPCEVTLVTDSQYVMKGITEWMVNWKKRGWKTAAKEPVKNADLWQLLDEQVSRHTVKWQWVRGHIGHPGNERADQLANRGVDEVRGIKRA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HI, RNase HI.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMM_ORYSI
Sequence: MAARKNAGVLALFDVDGTLTAPRKVVTPEMLQFMKQLREHVTVGVVGGSDLVKISEQLGKSVTTDYDYCFSENGLVAHKNGELIGTQSLKSFLGDDQLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFEKYDKVHNIRPKMVSVLREKFAHLNLTFSIGGQISFDVFPQGWDKTYCLRYLEEFQEIHFFGDKTYKGGNDYEIFESDRTIGHTVTSPDDTAEQCRSLFMSK
What is the function of this protein?
Catalyzes the interconversion of mannose-6-phosphate to mannose-1-phosphate, the precursor for the synthesis of GDP-mannose (By similarity).  GDP-mannose is an essential sugar nucleotide for the synthesis of D-mannose-containing cell wall polysaccharides (galactomannans and glucomannans), glycolipids, glycoproteins and the antioxidant L-ascorbate (Probable).
What are the official names of this protein?
Phosphomannomutase, OsPMM.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic PMM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_ACIB5
Sequence: MKTIKVTQTKSSSHRLKNHKLCLQGLGLRRIGHTVEVQDTPSNRGMINKVYYMVSVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GEDD_ASPTN
Sequence: MLLCDSLSFFQQLAWHVQLLACLQWLGRSQVLICLPLGSSFSVRDLAQLCGVSETTLSRVVRLTATAGFLQEPQPGQIMHTPLSGAFGGQPSLRDATLFLSNRITPSALQMASTLHLGRTESAAESAYNLAFATSRTFRDACRVTPKLHRQWIAYLRNTGDSDDSITEVLTRLDWAHLGRSCIVESGARSTTRARVLSKLYPALRFVVQLSGPDQDAHDTRASLTPVPSIPGIIQLDENYPHISVQTRNLGLAQPVLDAAVYILHLPSLSVANSPSRSIVVKELQAHMDVLSSNPSAVLIATARVLPPPGSVHREVEAMCRVRDFTLMQLTNEHEPEVADFDDLVNAVEAGGAGRLVVADKLRARNNLLVAFVLKYQEVSAPGALPSSF
What is the function of this protein?
Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of geodin, an intermediate in the biosynthesis of other natural products (PubMed:12536215, PubMed:24009710).  With gedR, coregulates the production of geodin (By similarity).
What are the official names of this protein?
Geodin cluster transcriptional coactivator gedD, Geodin synthesis protein D.
What are the subcellular locations of this protein?
Nucleus.
Protein: INS1A_CONGE
Sequence: MTTSSYFLLMALGLLLYVCQSSFGNQHTRTFDTPKHRCGSEITNSYMDLCYRKRNDAGEKRGRASPLWQRRGSLSKLKARAKRNGAFHLPRDGRGVVEHCCHRPCSNAEFKKYCG
What is the function of this protein?
This venom insulin, from a fish-hunting cone snail, facilitates prey capture by rapidly inducing hypoglycemic shock (PubMed:25605914, PubMed:27617429).  It is one of the smallest known insulin found in nature and lacks the C-terminal segment of the B chain that, in human insulin, mediates engagement of the insulin receptor (INSR) and assembly of the hormone's hexameric storage form (PubMed:27617429).  Despite lacking this segment, it both binds and activates human insulin receptor (long isoform (HIR-B)) with a high potency (EC(50)=16. 28 nM) (PubMed:30747102, PubMed:27617429).  In vivo, intraperitoneal injection of this peptide into zebrafish lowers blood glucose with the same potency than human insulin (PubMed:25605914, PubMed:30747102).  In addition, when applied to water, this peptide reduces overall locomotor activity of zebrafish larvae, observed as a significant decrease in the percentage of time spent swimming and movement frequency (PubMed:25605914).  When tested on a mouse model of diabetes, this insulin also lowers blood glucose with a 10-fold lower potency than human insulin (PubMed:30747102).
What are the official names of this protein?
Con-Ins G1a, Insulin 1.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1488_ARCFU
Sequence: MARPLRALIFGRFQPFHLGHLKVTKWALEKFDELVLLVGMANESHTVLNPFTAGERIWMMREALKDEGVDLSRIITATVPTMSVYVGHAFYIINLVPKVDSIITRNPVIAQVFHDAGLEVIAPPEFDRNLYRGSYIRKLMLEDGNWRELVPKKVAAIIDEIGGVERLKKAASRD
What are the official names of this protein?
Uncharacterized protein AF_1488.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
Protein: GLYA_STRPB
Sequence: MTMIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVMAAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQANAAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAILEQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPVHYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFKEALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQNLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIAHLIIKALVNHDQETILEEVRQEVRQLTDAFPLYKK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSHB_SOLLC
Sequence: MGSGCSSPSISLTTIATSHFQSQESLSNSLNFYSPTRFLEPHLLKSSKIFIPKSPLKCAKVPEMQTQLEDSAKPIVDPHDIDSKLVQKLANDALVWCPLRGLLVGDRNSERSGTIPGVDMVHAPVALIPMSFPESHWKQACEVAPIFNELVDRVSQDGEFLQQSLSRTRKADPFTSRLLEIHSKMLEINKLEEIRLGLHRSDYMLDEQTKLLLQIELNTISSSFPGLSCLVSELHRSLLQQYREDIASDPNRIPANNAVNQFAEALAKAWNEYGDPRAVIIFVVQAEERNMYDQHWLSASLRERHQVTTIRKTLAEIDALGELQQDGTLVVDGQAVAVIYFRAGYAPSDYHSESEWKARLLMEQSRAVKCPSISYHLAGSKKIQQELAKPNVLERFLENKDDIAKLRKCFAGLWSLDESDIVKDAIERPELYVMKPQREGGGNNIYGEDVRGALLKLQKEGTGSDAAYILMQRIFPKISHSILMREGISHKEETISELGIYGTYLRNKTEVLINQQAGYLMRTKVSSSDEGGVAAGFAVLDSIYLV
What are the official names of this protein?
Glutathione synthetase, chloroplastic, GSH synthetase, GSH-S, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic GSH synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL19_MOUSE
Sequence: MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
60S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_SORCY
Sequence: MTNLRKTHPLMKIINSSFIDLPAPSNISSWWNFGSLLGVCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDADKIPFHPYYTIKDILGVLLLILVLTSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAVIPLLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPYIIIGQLASILYFLLILVIMPITSLLENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NRG2_MOUSE
Sequence: MRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCAPLERNQRYIFFLEPTEQPLVFKTAFAPVDPNGKNIKKEVGKILCTDCATRPKLKKMKSQTGEVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVRVEDAGEYVCEAENILGKDTVRGRLHVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPVGYTGDRCQQFAMVNFSKHLGFELKEAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRRQMHHHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRREAETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSQEERRRAAMPPYHDSIDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAPPGPGPGSGPGADMQRSYDSYYYPAAGPGPRRSACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRTRGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGCGSASASDDDADDADGALAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPTRAKQDSGPL
What is the function of this protein?
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors.  Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors.  May also promote the heterodimerization with the EGF receptor.
What are the official names of this protein?
Pro-neuregulin-2, membrane-bound isoform, Pro-NRG2.
What is the protein family that this protein belongs to?
Belongs to the neuregulin family.
What are the subcellular locations of this protein?
[Pro-neuregulin-2, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein. Note=Does not seem to be active. SUBCELLULAR LOCATION: [Neuregulin-2]: Secreted.
Protein: HTF2_RHYMA
Sequence: QVNFSPGWG
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor 2, Adipokinetic hormone 1, RhyMa-AKH-1, Hypertrehalosaemic neuropeptide 2.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS17_PSELT
Sequence: MSKKRLTGVVVSNKMDKTVVVEVTRKLEHPVYKKYIQRSKKYYAHDEKNECKAGDTVLIEETRPLSKMKRWRVVEVLKREVIAEETLNTKESEEV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y5566_ARATH
Sequence: MENTQDFSPPHMDASRPSLGFPLGTALLLIIIFSLSGIFSCCYHWDKHRSLRRSLANGRPSADIESNPYKPKPPFPEMKKPQNLSVPVLMPGDNTPKFIALPCPCAPPRPEKLTVDVQTPPQSPPVKPARFPVPLY
What are the official names of this protein?
Uncharacterized protein At5g65660.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATPE_ECOHS
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: URM1_HUMAN
Sequence: MAAPLSVEVEFGGGAELLFDGIKKHRVTLPGQEEPWDIRNLLIWIKKNLLKERPELFIQGDSVRPGILVLINDADWELLGELDYQLQDQDSVLFISTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
Protein: CAPP_VIBVY
Sequence: MNEKYAALKSNVSMLGHLLGNTIQEAHGDEILEKVETIRKLSKSARAGNQADRNNLIEEIKSLPDEQLTPVARAFNQFLNLTNIAEQYHTISRHCDAHVCEPDAINTLFAKLGQNGINKLDTAQAIRELNIELVLTAHPTEITRRTMINKLVKINECLSKLELSDLSYKERHKTEKRLEQLIAQSWHSDVIRKQRPTPLDEAKWGFAVVENSLWEAVPDFLRELDEKLKDYLDQGLPIDARPVHFSSWMGGDRDGNPFVTHTVTREVLLLSRWKAADLYLKDINELISELSMTKCNDTVRQLAGEDEHEPYRAILKQLRTLLSDTKEILDAKINGQKLAVKAPLQSVEQLWDPLFACYQSLRECGMSMIAEGSLLDTLRRVKAFGVHLVRLDIRQESTRHADVLSELTRYLGIGDYNHWSEQDKIAFLTNELASKRPLLPRDWQPSEPVKEVLDTCKIIAAQSREAFGAYVISMAKTASDVLAVHLLLQESGCPYRMDVCPLFETLDDLNNAEAVIKQLMSIDLYRGFIQNHQMVMIGYSDSAKDAGVMAAGWAQYHAMEALVNVAEQEGIELTLFHGRGGTIGRGGAPAHAALLSQPPKSLKGGLRVTEQGEMIRFKLGLPDVAVNSFNMYASAILEANLLPPPEPKQEWRDLMEVLSQVSCEAYRSVVRGEPDFVPYFRQATPELELGKLPLGSRPAKRNPNGGVESLRAIPWIFSWSQNRLLLPAWLGAGEAIQYSIDKGHQALLEEMCREWPFFSTRLGMLEMVYLKCNSEISRYYDERLADKSLLPLGDRLRDQLQSDIKAVLNVENNENLMQSDPWGQESIRLRNIYIEPLNMLQAELLYRTRQAGVVSEELEEALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.