PharMolix/UniProtQA huggingface dataset:
Protein: HRH4_MOUSE
Sequence: MSESNSTGILPPAAQVPLAFLMSSFAFAIMVGNAVVILAFVVDRNLRHRSNYFFLNLAISDFLVGLISIPLYIPHVLFNWNFGSGICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAVSYRAQHTGIMKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTKDCEPGFVTEWYILTITMLLEFLLPVISVAYFNVQIYWSLWKRRALSRCPSHAGFSTTSSSASGHLHRAGVACRTSNPGLKESAASRHSESPRRKSSILVSLRTHMNSSITAFKVGSFWRSESAALRQREYAELLRGRKLARSLAILLSAFAICWAPYCLFTIVLSTYPRTERPKSVWYSIAFWLQWFNSFVNPFLYPLCHRRFQKAFWKILCVTKQPALSQNQSVSS
What is the function of this protein?
The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues.  Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist) (By similarity).
What are the official names of this protein?
Histamine H4 receptor, H4R, HH4R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENGB_FRATM
Sequence: MNYSKAKYIMGAAKVSQLPEDTGVEVAFAGRSNAGKSSALNTLTDQKGLARVSKTPGRTQLINLFDLGNNNRLVDLPGYGYAKVSESIKRQWQSEMENYLTSRKCLNGIVLLVDSRHELKEFDSLMIEMAISFDLNLHILLTKADKLNNKERAQANRMIESFLKTFVSTDKISYQLFSSLTKMGLDKFKEKLDTWYQ
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PSAC_DIOEL
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWNGCKAKQIASAPRTEDCVGCKRCESACPTNFLSVRVYLWHETTRSMGLSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: LEU1_LEPCP
Sequence: MSDQLIIFDTTLRDGEQSPGASMTRDEKLRIARQLERLKVDVIEAGFAASSNGDFEAVKAIADVIKDSTICSLARANDRDISRAAEALRGANRARIHTFIATSALHMEKKLRMSPDEVLEQARLSVRFARNLCGDIEFSPEDGYRSDPDFLCRVLEAVIDEGATTLNIPDTVGYAIPELYGNFIRNLRERVPNSDKAIWSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNCSLEEVVMAVKTRRDYFGLDLRVDTSQIVPASRMVAQTTGFVVQPNKAVVGANAFAHASGIHQDGVLKARDTYEIMRAEDVGWSANKIVLGKLSGRNAFKQRLQDLGIALESEAEVNAAFMKFKDLADRKSEIFDEDILALVSDEQSDNQAEHYRLLALSQHSEMGERPHAEVAFAAGDVEHHARSDGNGPVDASIKAIESKVGTGAELLLYSVNAITSGSTESQGEVTVRLQLGGRIVNGVGADPDIVVASAKAYLAALNKLHSKAERVAAQG
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: KDGD_BRASO
Sequence: MSKMTPQEMAAKIGSGLLSFPVTPFKADYSFDETTYRSNMDWLCGYDVAGLFAAGGTGEFFSLTAAEVPEVVKVAVDETKGRVPVLAGTGYGTAIAREIAMSAEKAGADGLLLLPPYLMHAEQEGLAAHVEAVCKSVKIGVIVYNRDNAILQPDTLARLCERCPNLVGYKDGIGDIELMTRVYTKMGDRLTYIGGLPTAETFALPYLDMGVTTYSSAVFNFVPEFATNFYAAVRKRDHATIHAGLKDFILPLIAIRNRKKGYAVSIIKAGMKVIGRDSGPVRLPLTDLTEAEMAELTALVKALPVAASAQQAAE
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: RS2_KINRD
Sequence: MAVVTMRQLLESGVHFGHQTRRWNPKMKRFLFTERNGIYIIDLQQSLSFIDRAYDFVKETVAHGGSIMFIGTKKQAQESIAEQARRVGMPFVNQRWLGGMLTNFQTVNKRIARMRELEQVDFDDVAGSGLTKKELLVLRREYDKLTKTLGGIREMTKVPSAVWIVDTNKEHLAVDEAKKLNIPVVAILDSNCDPDDVDYRIPGNDDAIRSVTLLTRVIADAVAEGLQVRHGGKSDAAEPLAAWEQDLLAGDEGVQSGGSESVATVEGSTAPEAAQAEAAEGQPAEAAAEAGDTAEAPVAGDEAPAEAAAQV
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SWNH2_METRA
Sequence: MINSDAQSAQKQVEVEKPDEKYSAPRLLPPIPDSYQPAKAITKIPATSSLEDILAILERDGGVILTDFVSLQELDKIDEELEPYTKSSIADDDSYNNFIGKKTLVIPGLVGKSDTIANILDTNETIDKLLKVILEERYPAVFEQHTEELVVDPLLSICMGFHVGHGSPRQALHRDDMIFSSKHRPDMKINEVDGFSCFLAGTRITRENGGTMVILGSHKWEHDRRGRPDEVSFLEMERGSAFIFLSTLAHGAGYNTIPGEVRKITNLVFCRGTLRTEENQFLCVPRSKVLKMSPKMQTLLGFKKPAGSWLGMVENEDPAKDLEAIYEKMLK
What is the function of this protein?
Dioxygenase; part of the gene cluster that mediates the biosynthesis of swainsonine (SW), a cytotoxic fungal alkaloid and a potential cancer therapy drug (PubMed:28381497, PubMed:32786262).  Swainsonine production occurs via a multibranched pathway and is dispensable for fungal colonization of plants and infection of insect hosts (PubMed:32786262).  The first step of swainsonine biosynthesis is the production of the precursor pipecolic acid (PA) via conversion of L-lysine (Lys) to 1-piperideine-6-carboxylate (P6C) by the aminotransferase swnA, the latter being further reduced to PA by the reductase swnR (PubMed:32786262).  PA can be converted from lysine by both the SW biosynthetic cluster and the unclustered genes such as lysine cyclodeaminase (PubMed:32786262).  The PKS-NRPS hybrid synthetase swnK uptakes and condensates PA and malonyl-CoA with and without skipping of the ketoreductase (KR) domain in order to produce 3 intermediates, 1-oxoindolizidine, (1S)-1-hydroxyindolizin, and (1R)-1-hydroxyindolizine; with the transisomer (1S)-1-hydroxyindolizin being predominant (PubMed:32786262).  The terminal thioester reductase (TE) domain of swnK is involved in reduction of the thioester bond to release the intermediate aldehydes (PubMed:32786262).  The oxidoreductase swnN could contribute to the reduction of 1-oxoindolizidine to (1S)-1-hydroxyindolizin and (1R)-1-hydroxyindolizine, contributing to the major route of SW production (Probable).  The dioxygenase swnH2 would be responsible for the oxidization of (1R)-1-hydroxyindolizine into (1R,2S)-1,2-dihydroxyindolizine and of (1S)-1-hydroxyindolizin to yield both (1R,2S)-1,2-dihydroxyindolizine and (1S,2S)-1,2-dihydroxyindolizine (PubMed:32786262).  The dioxygenase swnH1 then performs the conversion of the 1,2-dihydroxyindolizine epimers to SW (PubMed:32786262).
What are the official names of this protein?
Dioxygenase swnH2, Swainsonine biosynthesis gene cluster protein H2.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: STX19_HUMAN
Sequence: MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK
What is the function of this protein?
Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR).
What are the official names of this protein?
Syntaxin-19.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm.
Protein: FAR7_HEMMO
Sequence: ARSDNFVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-7, FMRFa-7.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CMOB_PSYCK
Sequence: MLNDTITHAERELYLTLLELAQQQPSAYEWLTRLPTWLNDIKDKANYAHAPAYQASVARLPNLTVNNVDLNSDVLTIEANLSESQRKQTMALLKQLMPWRKGPFQIGGQISSRQTVDTQDNSDTNAPILIDTEWHSDWKWQRVAPHLGNLKGRRVLDVGGGSGYHGWRMAGSGADTVIIIDPSCLFYHQFMAIRHFVGSADAHTYTHGTGRYRTHYIPVPLEALPEHSQLFDTVFSMGVLYHRQSPFEHLQQLKGQLVKGGELVLETLVIEGDANTVLVPHDRYAQMNNVYFLPSVAALIGWLEKAGFTEVRCVDVAVTSTEEQRKTEWMTYHSLADFLDPNDSSKTLEGYPAPLRATLIAKK
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: UREF_CUPPJ
Sequence: MTPLRQLISLLHLASPALPIGGFSYSQGLEAAIDIGCVRDADTAERWIRDSLLYVQAQCEAPLWLLLHRGWQAMDVDAVREWNGWFHATRETAELRLETEQMGWSLAKLVGQMGWGGDALREHLAVISPVCLPTAFAATCVALEIDEREGLAAYCFNWAENQVAAAIKAVPLGQVAGQHMLRRLHEAVLMTVDEAVQRAAETPPRLSTFSPMLGLLSSRHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_HELHP
Sequence: MEVLRRYVLVFTSLCMTLFAWGENLQSIEADFEQIAVNEDGVPTRYEGHIIGKMPSKVKWDYKAPLQKEIYMNKNEVIMYEPRLEQVSHSRLKDKADFLSILKSAKKHNDGTYHTKVDGIEYVLFIDKAQKPERIEFVDSMGVKTTLKLKNVKLNGAISDKKFVFVPPQGVEIVELHSR
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: EED_DANRE
Sequence: MKMRRKMSEPHGEAGNEMPNKKQKLSSDENSNPDLSGDDNDDAVSVESGTHPERPDTPTNTASAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHGQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTFDCSSSHPLLAVAGSRGIIRIINHITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADFDLLGEKIMSCGMDHSLKLWRLDSERLQRAIRGSYEYNPSKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGRMEDDIDRIKPNESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTLPRCTSAIRQTSFSRDSSILIAVCDDASIWRWDRLR
What is the function of this protein?
Polycomb group (PcG) protein.  Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity).
What are the official names of this protein?
Polycomb protein eed.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ESC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MMM1_MALGO
Sequence: MQGRAIWAEGPIHSFDLPSSSLERGGQALKSGASKTHAYMDEEVGTSTAEAWTWIVPSLSFIQGFMAGQAVLLMLFLGLFRYFFMTSSPGTRAQQQADLLQRVHAVRTSMDMRSHVPPYARVPYEQGVQACVQDLLSQVRYDPSEHAPESLDWLNVLVAQLLMSYRMSILNAGMCAGRNEDMDEPALPSTANAEKTAAKLALERVLNEAMQGRATKHFLDRLVVTDIDMGCRYPTFSHARVRPALHAKSTLVEIDFEYMDALTLGIDTRMWLHFPQWRFGSLAANLCMRVERFAGTLVLEIGTLPEPTPVQARVCLHPNFVLDAHLSTILGSKSKLQDVPKIEELFLARLRSWLEHNVVWPHFWHIPLPGIGTSPADPLA
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: SLD7_YEAS8
Sequence: MSRKLCTLNFTLSGKQGSLVIRDIQLWSNRPTASKSTSELRGQFIQYVDLAKLPLWVRSTNMNTYRCYSTSATAQAYFKSKLRNANRGIVIELSDKVDQRSQEPAYLIIFREKTELNCFQVDLTMKHEFDGQVTKLKQEIGKTRASVSKEGSIDIIIQQSQQRKIGTKTKVYRNVHINDKRLQFNETLSKLILGGLRLRGISNSITDYQKLYKITFDAAEFTHRDELKRISMGSVEEVSFESLQETVETLLKLFTKS
What is the function of this protein?
Required for the proper function of SLD3 at the initiation of DNA replication.  Binds to SLD3 and reduces its affinity for CDC45, a component of the replication fork.  Required for mitochondrial morphology (By similarity).
What are the official names of this protein?
Mitochondrial morphogenesis protein SLD7, Synthetic lethality with DPB11-24 mutation protein 7.
What is the protein family that this protein belongs to?
Belongs to the SLD7 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle pole.
Protein: YEBF_SALCH
Sequence: MNKRGALLSLLLLSASVSAFAASTESKSVKFPQCEGLDAAGIAASVKRDYQQNRIVRWADDQKKVGQADPVAWVNVQDVVGQNDKWTVPLTVRGKSADIHYQVIVDCKAGKAEYKPR
What are the official names of this protein?
Protein YebF.
What is the protein family that this protein belongs to?
Belongs to the YebF family.
What are the subcellular locations of this protein?
Secreted.
Protein: KATG_NOCSJ
Sequence: MTDSQDNRTPESPQGVDRKAEGGCPVLHDGVTAQGSESENPAIDSPTPRTGGRPNSLKDWWPNHLDLSVLHAHSSKSSPLDPGFRYSEEFEKLDIEALRRDIVEVLHTSQDWWPADFGHYGGLFVRMAWHAAGTYRIHDGRGGAGQGAQRFAPLNSWPDNANLDKARRLLWPVKQKHGQKISWADLIVFAGNVALEDMGFTTFGFGFGREDIWEPEEIYWGPEDTWLGDERYSGDRELSNPLGAVQMGLIYVNPEGPNGNPDPLASARDIRETFARMAMNDEETVALIAGGHTFGKTHGAGDADLVGPEPEAAPLEAQGLGWHSSFGSGKGEDTITSGIEVTWTYHPTRWDNEFFHILYAYEWELMKSAAGANQWRPKNGAGADMVPDAHDPSKRREPRMLTSDLALRFDPEYAKISSRFKDHPEEFALAFAKAWYKLLHRDLGPIARYLGPLVGETQIWQDPVPAVDHELVSDDDVAALKAKVLDSGLSVAELVSTAWASAASFRSTDKRGGANGARIRLEPQRSWAVNQPEQLAGVLDRLEGIQREFNEAGGAKISLADLIVLAGSAAVEKAAKDGGVDVTVPFRAGRTDASQEQTDVDSFAVLEPRADGFRNYLLENEKAQPEVLLVERAYLLGLTAPEMTVLVGGLRALGNNVGGSGHGVLTDRPGVLTNDFFANLLAPGAQWKASESEANVYEIRDLASGELRWTATAVDLIFGSNSQLRSLAEVYASADAREKFVRDFVAAWVKVMDADRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: CRK42_ARATH
Sequence: MRCLTKTRSFHYVIIFYSFFFLPFLSSSSDDQRTTVSGLFCGGRSKSSADPNYIPTFVEDMHSLSLKLTTRRFATESLNSTTSIYALIQCHDDLSPSDCQLCYAIARTRIPRCLPSSSARIFLDGCFLRYETYEFYDESVSDASDSFSCSNDTVLDPRFGFQVSETAARVAVRKGGFGVAGENGVHALAQCWESLGKEDCRVCLEKAVKEVKRCVSRREGRAMNTGCYLRYSDHKFYNGDGHHKFHVLFNKGVIVAIVLTTSAFVMLILLATYVIMTKVSKTKQEKRNLGLVSRKFNNSKTKFKYETLEKATDYFSHKKMLGQGGNGTVFLGILPNGKNVAVKRLVFNTRDWVEEFFNEVNLISGIQHKNLVKLLGCSIEGPESLLVYEYVPNKSLDQFLFDESQSKVLNWSQRLNIILGTAEGLAYLHGGSPVRIIHRDIKTSNVLLDDQLNPKIADFGLARCFGLDKTHLSTGIAGTLGYMAPEYVVRGQLTEKADVYSFGVLVLEIACGTRINAFVPETGHLLQRVWNLYTLNRLVEALDPCLKDEFLQVQGSEAEACKVLRVGLLCTQASPSLRPSMEEVIRMLTERDYPIPSPTSPPFLRVSSLTTDLEGSSTISHSTNSTTTFNTMVKTDQASYTSSESSTTRTI
What are the official names of this protein?
Cysteine-rich receptor-like protein kinase 42, Cysteine-rich RLK42.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RISB_SALA4
Sequence: MNIIKANVAAPDARVAITIARFNQFINDSLLDGAVDALTRIGQVKDDNITVVWVPGAYELPLATEALAKSGKYDAVVALGTVIRGGTAHFEYVAGGASNGLASVAQDSGVPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: Y487_STRU0
Sequence: MRKSFYSWLMTQRNPKSDEPVAILADLAFDDTTFPKHSDDFEVISRYLEDQAIFSFNLGHFDAIWEDYLNH
What are the official names of this protein?
UPF0346 protein SUB0487.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: HFQ_ECOL5
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PUR9_LEPBJ
Sequence: MIQIKRALISVSDKSDIVEFAQFLNQNGVEIISTGGTLKLLKDNGIQAIAIDDYTGFPEILEGRVKTLHPKVHGGLLGVVSNPAHKQKMEELKIPKIDLVVVNLYPFLKTVSKPGVQLEEAIENIDIGGPSMIRSAAKNYKHTLVLTDPSDYEEVRVLIASGGISEEVAAGYMRKAFSHTAMYDTAISSWFHKQAGDVFPDVLNLSFLKKQKLRYGENPHQAASFYEPLFVKSDFSPLQGKELSFNNMLDFDAAFHISSLLPENTVCIIKHLNPCGIAYADDPLEAFQLARRTDPISAFGGVIGIKGIVHGELATAITENFVEGVIAQKFTPEALELFSKKPNIRLIEIENFKEALDELDLRPIHHGLLIQERDYTTITEKDLKVVTKKQPTSDDIRGLMFAWSCVRFIKSNAIVYTEENATLGIGAGQMSRVDSVQLGANKALNVGLSVVGSYVASDAFFPFRDGIDALAKAGAKAIIQPGGSVRDAEVIQAADEHGLIMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: DNAK_RHILE
Sequence: MAKVIGIDLGTTNSCVAVMDGKDAKVIENAEGARTTPSMVAFSDDGERLVGQPAKRQAVTNPTNTLFAVKRLIGRRYEDPTVEKDKHLVPFTIVKGDNGDAWVEANGKGYSPAQISAMILQKMKETAESYLGEKVEKAVITVPAYFNDARPGQPRMPAASLGLEVLRIINEPTAAALAYGLDKKEGKTIAVYDLGGGTFDISILEIGDGVFEVKSTNGDTFLGGEDFDMRLVEYLVAEFKRDNGIDLKNDKLALQRLKEAAEKAKIELSSSQQTEINLPFITADASGPKHLTLKLTRAKLESLVDDLVQRTIAPCKAALKDAGVTAAEIDEVVLVGGMSRMPKVQEVVKQLFGKEPHKGVNPDEVVALGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIERNTTIPTKKSQTFSTAEDNQQAVTIRVSQGEREMAADNKLLGQFDLVCLPPSPRGMPQIEVTFDIDANGIVQVSAKDKGTGKEQQIRIQASGGLSDADIEKMVKDAEAHATEDKKRREAVEARNQAESLIHSSEKSLKDYGDKVSEADRTAISDAIAALKTASEASEPDADDIKAKTQTLMEVSMKLGQAIYEAQQAESGAAGMPPPKAGDNVVDADYEEIKDDDRKKSA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: IL3_CANLF
Sequence: MSSFPILHLLLLLLGCQVPQAQGRPFSTDLPKQYFTMINEIMEMLNKSPSPSEEPLDSNEKETLLEDTLLRPNLDVFLNASSKFHKNGLLIWNNLKEFLPLLPTPTPRGEPISIMENNWGDFQRKLKKYLEALDNFLNFKNKP
What is the function of this protein?
This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
What are the official names of this protein?
Interleukin-3, IL-3, Hematopoietic growth factor, Mast cell growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor.
What is the protein family that this protein belongs to?
Belongs to the IL-3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AEQL1_NEMVE
Sequence: MKSVIAVLVLSLVLVNFTQAAKDDRWKACRMKCYTESKLCMNNDSKCFDSQSCNSCIQQVYSPCFNRCQEMLRRREAFKRMFAFDEEN
What is the function of this protein?
Probable neuropeptide.
What are the official names of this protein?
Protein Aeq5-like1.
Protein: TCS1D_CAMTA
Sequence: MELATTGKVNEVLFMNRGEGESSYAQNSSFTQQVASMATPALENAVETLFSKDFHLQALNAVDLGCAAGPNTFAVISTIKRMMEKKCRELNCQTLELQVYLNDLFGNDFNTLFKGLSSEVIGNKCEEVPCYVMGVPGSFHGRLFPRNSLHLVHSSYSVHWLTQAPKGLTNREGLALNKGKIYISKTSPPIVREAYLTQFHEDFTMFLNARSQEVVPNGCMVLILRSRQSSDPSDMQSCFTWELLAKAIAELVSQGLIDEDKLDAFNIPCYFPSLEEVKDIVERDGSFTIDHMEGFGLDSLQMEENDKWVRGEKFTKVVRAFTEPIISNQFGHEIMDKLYDKFTHIVVSDFEAKLPKTTSIILVLSKIDG
What is the function of this protein?
Involved in the biosynthesis of caffeine (PubMed:26773541).  Catalyzes the conversion of 7-methylxanthine (7mX) to theobromine and of theobromine to caffeine (PubMed:26773541).
What are the official names of this protein?
Caffeine synthase 1, TCS1d.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: SDF2B_DROSE
Sequence: MLRQFIISRVGRRLQLPMITQSRLASDLDKTEYTTPGEIVDYDDPPHLPVPEYPVRPDEPLETRKQRLLYQSRKRGMLENDLLLSTFVAKHLKDFNAEQTAEYDQLINGVSNDWDIFYWATDTKPTPPQFDTEIMRLLKEHVKNHEKVQRIRQPDL
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2-B, mitochondrial, SDH assembly factor 2-B, SDHAF2-B.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CNBLA_ORYSJ
Sequence: MDSSRSSNSLDSGSSLTLGELACAALIPVLALVDAVVFAAAQCFQKRPPGLLPATLAARARRRAGGRLTFRELADLADESRCFSVNEVEALYELYKKISCSIVDDGLIHKEELQLALFRTPAGKNLFLDRVFDLFDEKKNSVIEFEEFIHAISVFHPNTPLEDKIDFSFRLYDLRQTGFIEREEVKQMVVATLLESEVQLSDDLVEAILDKTFEDADTDKDNRISKEEWKAFVLKHPSVIKKMTLPTLKDTTAAFPSFIFNTQVED
What is the function of this protein?
Acts as a calcium sensor.  CBL proteins interact with CIPK serine-threonine protein kinases.  Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
Calcineurin B-like protein 10.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
Protein: PA2B3_DABRR
Sequence: SLLEFGMMILEETGKLAVPFYSSYGCYCGWGGKATPKDATDRCCFVHDCCYGNLPDCNPKSDRYKYKRVNGAIVCEQGTSCENRICECDKAAAICFRRNLNTYSKIYMLYPDFLCKGELKC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 3, PLA23, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.