PharMolix/UniProtQA huggingface dataset:
Protein: ICAM4_HUMAN
Sequence: MGSLFPLSLLFFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQPGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGKTRWATSRITAYKPPHSVILEPPVLKGRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSESLERFTGLDLANVTLTYEFAAGPRDFWQPVICHARLNLDGLVVRNSSAPITLMLAWSPAPTALASGSIAALVGILLTVGAAYLCKCLAMKSQA
What is the function of this protein?
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).  ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins.
What are the official names of this protein?
Intercellular adhesion molecule 4, ICAM-4, Landsteiner-Wiener blood group glycoprotein, LW blood group protein.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. ICAM family.
What are the subcellular locations of this protein?
[Isoform Long]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform Short]: Secreted. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: CSPL9_POPTR
Sequence: MAKSNKIFTNTLRLLALAATVVAIVFMVTSHDSAQVLNLTFTAKYSNTPAFKFLVIGEAIAGGYTVISILLSFKGLFWRLIVILDMVTTVLLTSSISAALAIAQVGKKGNTHAGWLPICGQVPDFCDYVTIALIAGFAAAIIYFVLLLCSLYVVLSPIFVATP
What are the official names of this protein?
CASP-like protein 1C2, PtCASPL1C2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYC_AZOBR
Sequence: MPLDLYNTLTRRKERFEPMTPDRVGMYVCGPTVYDTAHIGNARPVVFDLLFRLLRRLYPAVTYVRNITASDDKIIDRRATTGADRGADQAHRGPLPRRHGPLNAAPTIEPRATHHISHMVALIGLLIEPATPTPRKGTCCSPCRRWRSTGQLSRRSLDEMIAGARVEVAPYKRDSSDFVLWKPSTDGQPGWDSPWGRGRPGWHIECSAMAKEHLGVTFDIHGGGLDLILPDHENEIAQSRCAHAGEPLARYWVHQRLRDRRGARRMSKSLGNLLHRGTSCWTEFPGGGHPLGVRPYRSRGLPEAEESKATLDRWYQALRGDPAPAQAELPFDVLAALEDDLNSPLAISHLHELASAVNKATGEAEKAAAKGRCRSAERWAAPETRSVVPLGAEGAAALSDADIQQRIEDRSAARKAKNYAEADRIRKELADLGIVLEDGPQGTTWKRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_ALTMD
Sequence: MTLAYAPTAQTITIRNDWTKAEVEALFAMPFNDLLFNAQVVHRQHFNPNEVQVSTLLSIKTGACPEDCKYCPQSARYDTGLEKERLLEIEKVIQRAKEAKQVGSTRFCMGAAWRNPRDRDMPYILKMVEEVKSLGLETCMTLGMLTRDQAVALKQAGLDYYNHNLDTSPEYYGDIITTRTYEDRLNTLENVRAAGMNVCSGGIVGMGETVSDRASMLVQLANLPEQPQSVPINMLVKVKGTPLDSVEDLDYFEFIRTIAVARIMMPKSHVRLSAGREAMNEQMQAMCFMAGANSIFYGCKLLTTSNPDTHEDVMLFKKLGINTERTRDYSDEAHQQVLEEEIAQQQEQAEGSNDLFIDATKPKVAAKQQHATEA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: SYC_BEII9
Sequence: MALQLYNTLTRQKDIFEPIDPANVRLYACGPTVYDFLHIGNGRMLIVFDLLFRVLRDLYGADHVRYVRNITDVDDKINARAAERGIDIRVLTDEMTAIFHEDAKALNCLPPTVEPRATEHMAEMIAIIEKLVANGHAYIAEGHVLFDVPSMPDYGKLSKRPLDDMIAGARVEVAPYKRSPTDFVLWKPAKPEEPGWESPWGRGRPGWHLECSAMSWKHLGEVFDIHGGGIDLVFPHHENEVAQTCSAFGHDVMANVWMHNGHLQVEGQKMSKSLGNFLTIRDVLKDWPGETVRFTMLKTHYRQPIDWTLSSLRESQRELDRWYPVARAFDQINPDNIPGIPSSFRDALQDDLNTPEAITILRRLYKDALETTDYAGVHLLLCGKLLGLFDQSLEKWKNWKPASFTVENVTFEDLIKEREEARAAKNWPKSDHLRDVLASYGIVLKDNKDGTTSWEAKR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_BACHK
Sequence: MKEMKVIIAGPRGRMGHEAVLLMERTEHFNLVAAVDYKHGGEKISDLPGMPALDAPIYADLHTCLEEVEADVLLDLTTPEVGKQHVTLAVERGLRSVIGTTGFTEEELKQLTETAKEKAVGTIIAPNFAIGAVLMMKFSQMAAKYFQDVEVIELHHDQKLDAPSGTAVKTVELIRQNRESKQQGHPNEVEQLEGARGANVDGIHIHSVRLPGLIAHQEVMFGGDGQMLTVRHDSFNRASFMSGVKLSIETVMNLDHLVYGLENIID
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP70_MYCTO
Sequence: MKVKNTIAATSFAAAGLAALAVAVSPPAAAGDLVGPGCAEYAAANPTGPASVQGMSQDPVAVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNAAFSKLPASTIDELKTNSSLLTSILTYHVVAGQTSPANVVGTRQTLQGASVTVTGQGNSLKVGNADVVCGGVSTANATVYMIDSVLMPPA
What are the official names of this protein?
Immunogenic protein MPT70.
What are the subcellular locations of this protein?
Secreted.
Protein: RL28_YERE8
Sequence: MSRVCQVTGKRPVSGNNRSHAMNATKRRFLPNLHSHRFWVEGEKRFVTLRVSAKGMRVIDKKGIETVLAEIRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CH60_SHESH
Sequence: MAAKEVLFGNDARVKMLAGVNVLANAVKVTLGPKGRNVVLDKSFGAPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIVTEGLKAVAAGMNPMDLKRGIDKAVIAAVAELKTLSQECADTNAIAQVGTISANSDETIGEIIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGSVELESPFILLVDKKVSNIRELLPILEGLAKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVIAEEIGLELEKATLEDLGTAKRVIITKDDTTIIDGTGEQDQIKARVAQIKIQAEESTSDYDKEKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALVRVASKIAEVEVINEDQKHGVVIALRAMEAPLRQIAANAGEEGSVVANNVKNGSGNYGYNAGNDTYGDMLEMGILDPTKVTRSALQFAASIAGLMITTEAMVGEVKEDAPAGDMGGMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLC_PSEAB
Sequence: MNAKHAPFRHYLDLADARLGSQVVAVSDEWFAPASRMLQAGEPVWKEGVFDDSGKWMDGWETRRKRFEGHDQAVIRLGVPGVLKGVDIDTRFFTGNHPPAASLDGCFCTEGDPDDSTSWSEVLPAVGLQGDSHHYHPIDDERPWTHLRLNIYPDGGIARLRLYGVPYRDWSSLPPGTALDLAAAVNGGRALACSDQHFGRMGNLLNPGRAINMGDGWETGRRRTPGHDWVIVALGHPGSIEAAVVDTLHFKGNYPESCSIQAAFVEGGNEARIEAQSLFWRELLPAQKLEMHQEHRFERHLNALGPITHVRLNIFPDGGVSRLRLFGSPQLP
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: DAPA_ECOLI
Sequence: MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLDLADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIA_PSEAE
Sequence: MLKRLLIAACTLLFAGSLLAATPAAKPHVLIATSLGEIEVELDPAKAPISVKNFLEYVDSGYYDGTLFHRVIPGFMVQTGGFSAGMQEKKTRAPIKNEADNGLLNERGTLAMARTGVVDSATSQFFINLTDNDFLNHGARDFGYAVFGKVVRGMGVVDQIAKVPTTRRNGFADVPSDDVVILSAKRL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  This protein is not essential for growth.  Presumably plays a role in signal transduction.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Rotamase A.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HBB_RANTA
Sequence: MLTSEEKAAVTGFWGKVKVDEVGAEALGRLLVVYPWTQRFFEHFGDLSSADAIMHNDKVKAHGKRVLDAFSDGLKHLDDLKGAFAKLSELHCDKLHVDPENFRLLGNVLVVVLARHFGKDFTPVLQADYQKVVTGVANALAHRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RCA_VIGRR
Sequence: MAASVSTVGAVNRAILNLNGSGAGASAPTSAFFGTSLKKAVASRVPNSKVTNGSFKIVAAEKEIEESQQTNKDRWKGLAYDISDDQQDITRGKGMVDPLFQAPMDAGTHYAVMSSYEYLSTGLRQLDNIKDGFYIAPAFLDKLVVHITKNFMTLPNIKVPLILGIWGGKGQGKSFQCELVFAKMGINPIMMSAGELESGNAGEPAKLIRQRYREAADLIAKGKMCALFINDLDAGAGRLGGTTQYTVNNQMVNATLMNIADNPTNVQLPGMYNKEENARVPIIVTGNDFSTLYAPLIRDGRMEKFYWAPTRDDRVGVCKGIFRTDGVPEEDITKLVDTFPGQSIDFFGALRARVYDDEVRKWISGVGVDATGKKLVNSKEGPPTFDQPKMSLDKLLQYGNMLVQEQENVKRVQLADKYLNEAALGNANEDAIKSGSFFK
What is the function of this protein?
Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4. 1. 1. 39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.
What are the official names of this protein?
Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic, RA, RuBisCO activase.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO activase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: END4_GEOSW
Sequence: MLKIGSHVSMSGKKMLLAASEEAVSYGANTFMIYTGAPQNTRRKKIEELNIEAGLAHMKEHGIEEIVVHAPYIINIGNTKNPDTFALGVEFLRSEIERTEAIGAKQIVLHPGAHVGAGPEAGIRKIIEGLNEVLTREQTVQIALETMAGKGSECGRSFEELAQIIDGVTHNEKLSVCFDTCHTHDAGYNIVDDFDGVLEEFDRIIGLDRLKVLHINDSKNPRGSRKDRHENIGFGHIGFAALNYIVHHPQLADIPKILETPYVGEDKNNKKPPYKHEIAMLRAQVFDEELLTKIMNDE
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: EXOS6_XENTR
Sequence: MPGDSRRIRGPEESQSPLLYVLSEEGGKAAGRRGRGPSEPRPVFVRAGLLSQAKGSAYLEAGSGGTKVLCAVHGPRERGMGGERAETRGRLLCDLRWAPFSRRGPWSGSCPAGPSPRQAGLQLQESLEPAVRLDRYPRAEVIVWVLVLEDRGSALPAAVSCASLALADAGIEMFDLALGCGLSRGPGGELLLDPDDDEEEAGSGGTMSLSLLPTLNQVSGLISSGEWEGESSEEAVRLCMEGCQRLYPVLHQCLVKATKRKIPVPQPDTN
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.
What are the official names of this protein?
Exosome complex component MTR3, Exosome component 6, mRNA transport regulator 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus.
Protein: EFEB_ECOLI
Sequence: MQYKDENGVNEPSRRRLLKVIGALALAGSCPVAHAQKTQSAPGTLSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLTQGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKMTRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHAARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQFRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKVIALDSHIRLANPRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALEEYVKPIGGGYFFALPGVKDANDYFGSALLRV
What is the function of this protein?
Involved in the recovery of exogenous heme iron.  Extracts iron from heme while preserving the protoporphyrin ring intact.  Also displays peroxidase activity on guaiacol in vitro.
What are the official names of this protein?
Deferrochelatase, Peroxidase EfeB.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family. EfeB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: CFL2_ARATH
Sequence: MADITEYLERSMQNCSLIDRRSSMGDGFGMSDEHIPISDRFLELSSHFSVPSHLEQCLDLKTGEIYYRSWNSGMRVKEDPRKSMSRGNYADQSSGESSGTVFSSEEVSSYYESEESSSESSPSSRKYHKEEQDEDVLVVAGCKACLMYFMVPKLFKDCPKCATQLLHFDQLHSTSP
What is the function of this protein?
May regulate negatively the cuticle development by interacting with the HD-ZIP IV transcription factor HDG1.
What are the official names of this protein?
Protein CURLY FLAG LEAF 2, AtCFL2.
Protein: SURF1_RICFE
Sequence: MKTNLVVLITFTILISLGFWQLSRLKEKKLFLASMQANLTSPAINLAEIQDSLPYHKVKITGQFLPNKDIYLYGRRSMSSGKDGYYLVTPFKTIEDKVILVARGWFSNRNKIIITQATNDRQHEIIGVTMPSEKTRSYLPANDIKNNVWLTLDLKEASQTLELNLEDFYIIAEGKDISNLDILLPLSINHLAAIRNDHLEYALTWFGLAISLIVIYVIYRRNVISV
What are the official names of this protein?
SURF1-like protein.
What is the protein family that this protein belongs to?
Belongs to the SURF1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KI104_MEDTR
Sequence: MSTRSLTIFILAHVWLLMATTSIAQFVIDTSGEPVEDDEEYFIRPAITGNGGGSTLVTGNGPCPLHVGLDNTEGTLGVAVKFTPFAPQHDDDDVRLNRDLRVTFLTSTSCGQSTDWRLGEKDATSGRRLIVTGRDNGAGSQGNFFRIVQTQTGGTYNIQWCPTEACPSCKVQCGTVGVIRENGKNLLALDGDALPVVFQKE
What is the function of this protein?
Protease inhibitor involved in the control of mycorrhiza establishment and arbuscule development during root colonization by arbuscular mycorrhizal (AM) fungi (e. g.  Rhizophagus irregularis).
What are the official names of this protein?
Kunitz type trypsin inhibitor 104.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, apoplast.
Protein: FHL1_CANAL
Sequence: MSHIDGDDHMTKDLIDSLESKDNDLSLVTSNTQIPDVEVANLTHDADEINQLFDTATNNVLPESNKKDKPIDTQDLHEDDPKAVPKTTSNGESTSNSNSVSPKLLPNDGKSTPKIQKELRRKSTFVPVTSNSKSLEPSEDDNNNNNNNSRISAYARLDFENFTFFVQTLQVVLGRKSNDETLQQNVDVHLSSKKAISRRHAKIFYNFGTQRFEISILGRNGAFVDNVFVEKGLTIPLTDGNKIQIGDIPFKFVLPSNEPNEENNNQDSSEKQFNPSDAINLRSNLYSKSSSPQSSPKRKPQPSKKVKKEPVSASNTSKDIKPTPPVPTTAISPTASISTSTNAATAATATTPATTTAARKNSINRRNSLLKIRRLSNARRKSLAANDEINELLKDLGVTSIDEINEEDSELLDAQIQSLLDEDNENLGGIEDSLMKLAEFNESAIDDDDDDEEGNENSQADLDRLEKTMEHDAIDDEIKAIDSNLTLLDDEISKLTPLINDTNQGLLEEKETKKKQLEEEKRKKQLQQLQHKNSLAKFPRRSAPLMGKPASIQPPASSSIYSRINGLDKIGKTVSPRPPPPKLIAPVLRVTAEPSAIRSRPPLRAITVSDSSYIATFSYPKTIEEPSKYPKPKVKKEHHKKHSKKVYSLDEIPEPYRSKPNISFQIMITNVLKTEAARNGLIINEITEAIKEVYPYYKYCTDGWQFSINHCIKFTKIYKRLQKRGSEWLYAMDELYINERENIRIKQREIAKAKAKAEALRQEEIRQRQRLEAQKSLPHNIVGRNFASPYANTRVPPNQYNQFSQSSSSSSSSATTTTNGQYGSTTMVGGTSPQAGSIRAQLAAVRGNGNTPATTSTTPSLPAMNDPKTKKSLEYLQKELFTLYKARKLTYDTQTATSLITKAVATTIAQVNSIGAKAGAGDNALVFLVERAPEKVSKILDIALTKSIKEHEGIASKSPSQPATPGMRPEQLTTTSQSAATPTTTPQISNLQSLPVKPPISTPLPQVPQQQVSGVNIPGPIATPNIGVTSGVGNLGTTSIGTPTPTQIQSPATSVIPAMQSPQKPVSTPIPTSVPVPLPVPSAPLARPPSFGKPPGAGSSLSRPKAFGKPPGAGSSLSRPPTFLSNKPSYKRELEDDEEEGEQATNKIAKTE
What is the function of this protein?
In complex with IFH1, acts as a transcriptional regulator of rRNA and ribosomal protein genes.  The FHL1-IFH1 complex is targeted to the ribosomal protein genes by the DNA-binding factor TBF1.
What are the official names of this protein?
Fork-head transcriptional regulator FHL1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MACB_PSYA2
Sequence: MSSQDLYANAATDKPLMQVKGLIREFKAGEQTIRVLHDINLTIHQGEMVAIIGQSGSGKSTLMNILGCLDQATAGDYQVFGQSVNRLAPDELAKLRREHFGFIFQRYHLLGDISARDNVSVPAVYAGMDGQARNERAEQLLSDLGLADKVNNRPSQLSGGQQQRVSIARALMNGGDIILADEPTGALDSKSGKDVVQILKNLNAQGHTIIMVTHDPGLAAQAERVIEIKDGYIIADYKNEDYQRPVAQFSSIIDKHRKSAFGSFIDRLLESFKMSLLAMRAHKMRTLLTMLGIIIGIASVVSVVGLGKGSQEQILSNISSLGTNTITITDGYPYGDPRRQYNDDNLTPQDAQAVADQPYVLSVSPQLNSNMSVRYRNVQEAASISGVGKDYLDVSGETLAMGQGFDEQSILRRTQDIIIDSNAHKTFFPTTANPIGEVLLIGSVPGRVIGVLEPNEGGFSRSVDSPTLYMPYTTMMSRLIGSAYIESFVALIDNNISSSAAESAISNLMKSRHGTDDFRIRNSDSIRQTIESTTAAMTLLISSIAIISLIVGGIGVMNIMLVSVTERTNEIGVRMAVGARQSDIMQQFLIEAVLVCILGGLLGIGMAFAIGELINRVGGDSFKVIYSSTSIIAAFVCSTLIGVVFGFLPARNAAKLDPVEALSRD
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSUD_ECOLU
Sequence: MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGYTGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGRALFNLVTGSDPQELAGDGVFLDHRERYEASAEFTQVWRRLLLGETVNFNGKHIHVRGAKLLFPPIQQPYPPLYFGGSSDVAQELAAEQVDFYLTWGEPPELVKEKIEQVRAKAAAHGRKIRFGIRLHVIVRETSDEAWQAAERLISHLDDETIAKAQAAFARTDSVGQQRMAALHNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPHLEEAYRVGELLFPHLDVAIPEIPQPQPLNPQGEAVANEFIPRKVAQS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: VME1_CVBLY
Sequence: MSSVTTPAPVYTWTADEAIKFLKEWNFSLGIILLFITIILQFGYTSRSMFVYVIKMIILWLMWPLTIILTIFNCVYALNNVYLGFSIVFTIVAIIMWIVYFVNSIRLFIRTGSWWSFNPETNNLMCIDMKGRMYVRPIIEDYHTLTVTIIRGHLYMQGIKLGTGYSLSDLPAYVTVAKVSHLLTYKRGFLDRIGDTSGFAVYVKSKVGNYRLPSTQKGSGMDTALLRNNI
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: RL2_YERPA
Sequence: MAIVKCKPTSPGRRHVVKVVNPELHKGKPYAPLLEKLSKSGGRNNNGRITTRHIGGGHKQHYRLVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVARDGSYVTLRLRSGEMRKVQADCRATLGEVGNAEHMLRVLGKAGASRWRGIRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NUOA_SALA4
Sequence: MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARHKNVPFESGIDSVGTARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLARIGALDWTPARSRRERMNPETNSIANRQR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UPPP_VIBPA
Sequence: MSYFEAFILALIQGLTEFLPISSSAHLILPSAIFGWADQGLAFDVAVHVGTLMAVVIYFRHEVITLFRALFASIFKGDRSKEAKLAWMIVIATIPACVFGLLMKDVIEVYLRSAYVIATTTIVFGLLLWWVDKNAKLVADEYQTGWKKAVFIGIAQALAMIPGTSRSGATITAALYLGFTREAAARFSFLMSIPIITLAGSYLGMKLVTSGEPVHVGFLLTGILTSFISAYICIHFFLKMISRMGMTPFVIYRLILGVGLFAFLLSA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EIF3H_DROPS
Sequence: MANRGGRHARTEDSDNTINYVQCDGLAVMKMVKHCHEESSNMDLAQGALLGLVVDKCLEITNCFPFPKSGDETMDEEMYQLTVMRRLRRVNVDHLHVGWYQSSDVGNSLSLALLESQYHYQTSIEESVVVVYDTQKSARGFLCLKAYRLTPQAIQMYKDGDFTPEAFRTLKVGYESLFAEIPIVIKNSPLTNIMMSELNELLPEDKGHNFLDLGTASVLENHMRSLIERVDELYQEAVRYNKYQQVVFKQDSDKNRALAKLAAENAVRTSKGEPTVAEEEVIKQFRPMPVPARLTATITSGQINTHSQHIAQFCSQSLAKLFITESLQNAKEAKEIK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h, Eukaryotic translation initiation factor 3 subunit 3.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_STAA9
Sequence: MEMKPKYDPREVEAGRYEEWVKNGYFKPSEDKSKETYTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGITRYDLGREKFLEQAWDWKEEYASFIRAQWAKLGLGLDYSRERFTLDEGLSKAVKKVFVDLYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADGEGFIEIATTRPETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIDFGSGAMKVTPAHDPNDFEIGQRHQLENIIVMDENGKMNDKAGKYEGMDRFDCRKQLVKDLKEQDLVIKIEDHVHSVGHSERSGAVVEPYLSTQWFVRMEDLAKRSLDNQKTDDRIDFYPQRFEHTFNQWMENIRDWTISRQLWWGHQIPAWYHKETGEIYVGEEAPTDIENWQQDEDVLDTWFSSALWPFSTLGWPDLESEDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVLLHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVESVWNFINKIWNGARFSLMNIGEDFKVEDIDLSGNLSLADKWILTRLNETIATVTDLSDKYEFGEVGRALYNFIWDDFCDWYIEMSKIPMNSNDEEQKQVTRSVLSYTLDNIMRMLHPFMPFVTEKIWQSLPHEGDTIVKASWPEVRESLIFEESKQTMQQLVEIIKSVRQSRVEVNTPLSKEIPILIQAKDKEIETTLSQNKDYLIKFCNPSTLNISTDVEIPEKAMTSVVIAGKVVLPLEGLIDMDKEISRLEKELAKLQSELDRVDKKLSNENFVSKAPEKVINEEKRKKQDYQEKYDGVKARIEQLKA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.