PharMolix/UniProtQA huggingface dataset:
Protein: MATK_CRYJA
Sequence: MGEFQRNENKHKSWQQFFLYPLFFREDLYAIAHDHHLDRSGSSEPTEILVSNFLSFLTVKRSIRRMRKQTNSISLFGNSDPNKLIECNKNFYSKSILEGFTIVLEVSFAMRSKHFIEGMNGWNSLRSIHCLFPLMEDKLPHSNYISDIRVPYSIHPEILVRIFRRWIRDAPSLHLLRSILHEWKNSFSRENLQKALITQIENTRFSLFLWNSYVYECESFLIPLIKRFFNSQSLLYGSFPDRTHFDKKIKDIVLFPRKISTKKIWLLKDSFIHYVRYGERSLMALKGTHLQVKKCRYHLFHFWQYYFHLWFQPYRICSLQLSKTSFSFLGYFLHVKMKPLVVRVKMLDDLFITDLITNELNPIAPIRAILFFLAKEKFCDISGWPISKLSWTSLSDDDILDRFDRIWINLFHYYSGSINQEGLYHIKYILLLSCAKTLACKHKSTIRVVREQLGSELFTKSFSKEKFISSSFSKTRSQRERIWNSEISQINPLANFWQKMQNKQIEN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LGT_RICAH
Sequence: MTFPNINPIIFYLGPLAISWYSLSYVVGILLSWFYANKIIEKFKPQINKKTLEDFITYAVIGIIVGGRLGFVLLYNPSRYFLHPIDILKTYEGGMSFHGGALGVIIAAYLFCRKYKVNFLSLTDIIAAVVPIGLFLGRIANFINGELYGRITNASFGMIFPNSDLMPRHPSQLYEAFFEGLVLFCILAYATFKNKTLKNCGLNSGLFLTFYALFRIAIEIFREPDIQIGFILDNLTMGQILSVPMLILGSYLICQSNPK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRC_CLOAB
Sequence: MIIIKNGYVIDPLTKREGKFDILIDGENVVRISQDIGIDDDIEVIDAEDCIVSPGFIDIHSHFRDPGFTEKEDIITGARAAARGGYTTVICMANTNPVVDNVETLRYIVDKAKTAKIEVLQVGTITKGMQGVELVDMEALKEAGAVGFSDDGKPIMDSRLVLEAMQKARELDVPLSFHEEDPKLVYESGINGGKVAEKLNMMGALEEAETVLTARDAALAVSSGAKTNIQHISSKISLGIIKLAKEMGANIIAEATPQHFSITEEEILNCGTNAKVNPPLRREDDRKAIVAALKDDTIQVIATDHAPHTKDEKAREFKEAPSGMIGLETALSLAVTNLVKTGDLTYRDMISKLTINPARFYNLDRGYIKEGHRADIVIFDPDEKYTVKEEEFQSKASNSPFIGKELFGKVKTTIYNGKIVYEDK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: ECPR_ECO27
Sequence: MTWQNDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKDFVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAGLSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMLPKSIARIENCSVKTVYTHRRNAEAKLYSKLYKLVQ
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity).  Positively regulates the expression of the ecp operon by binding to two TTCCT boxes.
What are the official names of this protein?
HTH-type transcriptional regulator EcpR.
What is the protein family that this protein belongs to?
Belongs to the EcpR/MatA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDE_HUMAN
Sequence: MGHSKQIRILLLNEMEKLEKTLFRLEQGYELQFRLGPTLQGKAVTVYTNYPFPGETFNREKFRSLDWENPTEREDDSDKYCKLNLQQSGSFQYYFLQGNEKSGGGYIVVDPILRVGADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQTLGLSRSCYSLANQLELNPDFSRPNRKYTWNDVGQLVEKLKKEWNVICITDVVYNHTAANSKWIQEHPECAYNLVNSPHLKPAWVLDRALWRFSCDVAEGKYKEKGIPALIENDHHMNSIRKIIWEDIFPKLKLWEFFQVDVNKAVEQFRRLLTQENRRVTKSDPNQHLTIIQDPEYRRFGCTVDMNIALTTFIPHDKGPAAIEECCNWFHKRMEELNSEKHRLINYHQEQAVNCLLGNVFYERLAGHGPKLGPVTRKHPLVTRYFTFPFEEIDFSMEESMIHLPNKACFLMAHNGWVMGDDPLRNFAEPGSEVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATYFQGVRLDNCHSTPLHVAEYMLDAARNLQPNLYVVAELFTGSEDLDNVFVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCLRPLMPAIAHALFMDITHDNECPIVHRSAYDALPSTTIVSMACCASGSTRGYDELVPHQISVVSEERFYTKWNPEALPSNTGEVNFQSGIIAARCAISKLHQELGAKGFIQVYVDQVDEDIVAVTRHSPSIHQSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERNTKPYRKDENSINGTPDITVEIREHIQLNESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSPHFKSGSLAVDNADPILKIPFASLASRLTLAELNQILYRCESEEKEDGGGCYDIPNWSALKYAGLQGLMSVLAEIRPKNDLGHPFCNNLRSGDWMIDYVSNRLISRSGTIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDTAWKQMSSFVQNGSTFVKHLSLGSVQLCGVGKFPSLPILSPALMDVPYRLNEITKEKEQCCVSLAAGLPHFSSGIFRCWGRDTFIALRGILLITGRYVEARNIILAFAGTLRHGLIPNLLGEGIYARYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDSAPLPAGTLDQPLFEVIQEAMQKHMQGIQFRERNAGPQIDRNMKDEGFNITAGVDEETGFVYGGNRFNCGTWMDKMGESDRARNRGIPATPRDGSAVEIVGLSKSAVRWLLELSKKNIFPYHEVTVKRHGKAIKVSYDEWNRKIQDNFEKLFHVSEDPSDLNEKHPNLVHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTTEKAWKALEIAEKKLLGPLGMKTLDPDDMVYCGIYDNALDNDNYNLAKGFNYHQGPEWLWPIGYFLRAKLYFSRLMGPETTAKTIVLVKNVLSRHYVHLERSPWKGLPELTNENAQYCPFSCETQAWSIATILETLYDL
What is the function of this protein?
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
What are the official names of this protein?
Glycogen debranching enzyme, Glycogen debrancher.
What is the protein family that this protein belongs to?
Belongs to the glycogen debranching enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Under glycogenolytic conditions localizes to the nucleus.
Protein: NHAB_ECO5E
Sequence: MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAGWLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKVREVLQQFDDQSRHQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSLTGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLFYIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMGWIATL
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNAR1_MOUSE
Sequence: MEANQEASLFLVKILEELDSKQNTVSYQDLCKSLCAQFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCSVNNQQSKKIMVAADIVTIFNLIQMNGGTAKEKLPMSCHKVRKKEASFESCRSDTEVCSPTVCEPLNCELSERPFSRGYPTRQSSKCRKMDCKECPQFVPASEPNFLLGVSKEVKNRAASLDRLQALSPYSVASPQPCEMQRTYFPMNIENEPMSDQDSLPISQGIKETFISSEEPFVVQSCVQKRNIFKEDFHNLMTVSPSLVGTTNKAEEGHGEPQSQKELHKPPFFNHSFEMPYHNQYLNPVYSPIPDKRRAKHESLDDLQASTYFGPTPVMGTQDTRRCPGRSSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSGSQTPNFSGPDRHPVYLVPKDQQKVLPAGYAVKPNGLKSKEISSPVDLEKHEAVKKFKDKSISCTSGQHSSDTSSVGTQTEQHVLDPPKCKDLCTSGQAKYGDRHAMKQSDDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHHLAKITNGVSSGKGDKCNRPENVHHSEEELKSSVCKLVLRIGEIERKLESLSGVREEISQVLGKLNKLDQKIQQPEKVNVQIDLNSLTSEAPSDDSASPRVFRAHSGSHGPKLENSPDWCCSDASGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYTNRMSLNEEEIKDAGPANNKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHPYPTSLKGHMKSNPLYTDMRLTELAEVKRGQPSWTIEEYARNSGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALITAAACTVILVIVVPICTMKS
What is the function of this protein?
Intrinsically disordered protein which may negatively regulate mTOR signaling pathway by stabilizing the mTOR complex component DEPTOR.  Negatively regulates angiogenesis.  Negatively regulates cell growth (By similarity).  Negatively regulates neurite outgrowth in hippocampal neurons (By similarity).
What are the official names of this protein?
Major intrinsically disordered Notch2-binding receptor 1, Membrane integral NOTCH2-associated receptor 1, Protein DD1, Ubiquitination and mTOR signaling protein.
What is the protein family that this protein belongs to?
Belongs to the MINAR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type IV membrane protein.
Protein: TREF_ECOLU
Sequence: MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRYLWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKLIEKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCM_ECOLI
Sequence: MRLIITFLMAWCLSWGAYAATAPDSKQITQELEQAKAAKPAQPEVVEALQSALNALEERKGSLERIKQYQQVIDNYPKLSATLRAQLNNMRDEPRSVSPGMSTDALNQEILQVSSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLGTLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQLDAYLQALRNQLNSQRQLEAERALESTELLAENSADLPKDIVAQFKINRELSAALNQQAQRMDLVASQQRQAASQTLQVRQALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQQLDTEMAQLRVQRLRYEDLLNKQPLLRQIHQADGQPLTAEQNRILEAQLRTQRELLNSLLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDLRRLISLDTFSQLGKASVMMLTSKETILPLFGALILVGCSIYSRRYFTRFLERSAAKVGKVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVTATVPLLWVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDREFSGSLGRLCFILICGALAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMIGAPLVAILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRRWMLIQRRRLAFDRAKHRRAEMLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLWSEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLELAILQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFGLQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNKAFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVIDNPAPEVFLVDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNGKQTGRTLTSAGKGRQAGSL
What is the function of this protein?
Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed.  Gates spontaneously in response to increased membrane tension.
What are the official names of this protein?
Miniconductance mechanosensitive channel MscM.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YQGF_BACP2
Sequence: MRILGLDLGTKTLGVAISDEMGWTAQGIETIKIDEAGGDFGLSRLSEIVSQYGTDKIVLGFPKNMNGTVGPRGEASQSFAKVLENTYNVPVVLWDERLSTMAAEKMLISADVSRQKRKKVIDKMAAVMILQGYLDSLN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNPI2_BOVIN
Sequence: MRLVILDNYDLASEWAAKYICNRIIQFRPGQDRYFTLGLPTGSTPLGCYKKLIEYHKNGDLSFKYVKTFNMDEYVGLPRNHPESYHSYMWNNFFKHIDIDPNNAHILDGNATDLQAECDAFEKKIKEAGGIDLFVGGIGPDGHIAFNEPGSSLVSRTRLKTLAMDTILANAKYFDGDLSKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTIFVCDEDATLELRVKTVKYFKGLMHVHNKLVDPLYSMKEGN
What is the function of this protein?
Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway.  Deamination is coupled to aldo-keto isomerization mediating the metabolic flux from UDP-GlcNAc toward Fru-6P.  At high ammonium level can drive amination and isomerization of Fru-6P toward hexosamines and UDP-GlcNAc synthesis.  Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and their effects on hyaluronan synthesis that occur during tissue remodeling.
What are the official names of this protein?
Glucosamine-6-phosphate isomerase 2, Glucosamine-6-phosphate deaminase 2, GNPDA 2, GlcN6P deaminase 2.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBG_KLULA
Sequence: MGELPYKIQELKLRRIEELNNKLRNELARERMTASNACLSIIDYTSTHKDYAVPEVWGYPMVGENPYNNTMRKNNFARSHEETSACCTIM
What are the official names of this protein?
Guanine nucleotide-binding protein subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: TXS6B_CUPSA
Sequence: LNPFRWMINKYREWKNKKN
What are the official names of this protein?
Short cationic peptide-6b, SCP-6b, Short cationic peptide-6h, SCP-6h, Truncated variant of Cupiennin 6 family.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EXP21_ARATH
Sequence: MKLLEKMTYVECFMIIMATWFMFISYSHGANVAAAPGTNGLDTAWYDARAAYYGDIHGGGTELEGACGYGDLNKHGYGLATAALSTALFNSGASCGACYEIMCSPNPQGCLSGSIKITATDLCPPGSAWCYLPNKHFDLSLPMFIKIAQVKAKMVPVRYRRVPCAKTGGVKFEVKGNPNILTILPYNVGGAGDIIAVSAKGSKTAWVVMSRYWGQNWTTNVNLTGQSVSLRVTTSDGITKDFTDVMPASWGFGQTFDGKTNF
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Expansin-A21, AtEXPA21, Alpha-expansin-21, At-EXP21, AtEx21, Ath-ExpAlpha-1.20.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: CTPC_MYCMM
Sequence: MTLAIVKEVPAGADGDDTTDLVVLSDAAGRMRVRADWVRGNSRRAVAVEEAVAKQDGVRVVHAYPRTGSVVVWYSPRRCDRAAVLEAIGGAKHVAAELIPARAPHSTEIRNTDVLRMVIGGAALALLGVRRYVFARPPLLGPSGRMVATGVTIFTGYPFLRGALRSLRSGKAGTDALVSAATIASLILRENVVALTVLWLLNIGEYLQDLTLRRTRRAISELLRGNQDTAWIRLTDGPEAGTEVQVPIDSVQIGDEVVVHDHVAIPVDGEVVDGEAIVNQSAITGENLPVSVVAGATVHAGSVVVRGRLVVRAQAVGNQTTIGRIITRVEEAQNDRAPIQTVGENFSRRFVPTSFIVSAITLLVTGDVRRAMTMLLIACPCAVGLSTPTAISAAIGNGARRGILIKGGSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIIAMHKDWEPEQVLAYAASSEIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLLLGSPSLLESEQVKVSKKASEWVGKLRQQAETPLLLAVDGTLVGLISLRDEVRPEAAEVLTKLRDNGVRRIVMLTGDHPDIAKVVAEELGIDEWRAEVMPEDKLEVVRDLQDEGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETADVALANDDLHRLLDVRDLGGRAVDVIRQNYGMSIAVNAAGLLIGAGGALSPVLAAILHNASSVAVVANSSRLIRYRLE
What is the function of this protein?
Zn(2+) efflux transporter which is involved in detoxification of zinc during infection.
What are the official names of this protein?
Zinc-exporting P-type ATPase, Zn(2+) efflux pump CtpC.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABZ_STAAE
Sequence: METIFDYNQIKQIIPHRQPFLLIDKVVEYEEGQRCVAIKQVSGNEPFFQGHFPEYAVMPGVLITEALAQTGAVAILNSEENKGKIALFAGIDKCRFKRQVVPGDTLTLEVEITKIKGPIGKGNAKATVDGQLACSCELTFAIQDVK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATLA1_MACFA
Sequence: MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEVFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQSKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQGSTNEALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKKM
What is the function of this protein?
GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes.  Functions in endoplasmic reticulum tubular network biogenesis.  May also regulate Golgi biogenesis.  May regulate axonal development.
What are the official names of this protein?
Atlastin-1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, axon. Note=Localizes to endoplasmic reticulum tubular network.
Protein: PAT_ECO55
Sequence: MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: LGT_PSEE4
Sequence: MLPYPQIDPVAVALGPLKIHWYGLMYLIGIGGAWLLASRRLNRFDPTWSREKLSDLVFWLSMGVIVGGRLGYVLFYDLHQYLANPTLIFEVWKGGMSFHGGFIGVMLAALWFGKRNNKSFFELMDFVAPLVPIGLGAGRIGNFINAELWGKATDVPWAMVFPPFSDPAQLPRHPSQLYQFALEGVALFVILWLYSRKPRPTMAVSGMFALFYGIFRFIVEFVRVPDAQLGYIAFGWLTMGQLLCVPMIVGGIFLIWLAYNRKPTAKATV
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EGCR1_ASPFM
Sequence: MGVLRLRVDGQTFRDPDNREITLRGINVAGEAKYPKKPDIPSYVSDGFFDADNVSFVGRPFSLDDAHTHFSRLRKWGYNTIRYVFTWEAIEHEGPGKYDDEWISFTIEVLRIAKQYGFYVFLDPHQDVWSRLSGGSGAPAWTLYAAGFDPRGFKKTEAALVQNTFDDPAEFPKMIWSTNYTRLVSQTMFTLFYGGRDFAPKAIIDGINIQDYLQGHFIAACRYFAQKIHEAGDIENEVVIGWESMNEPNRGLIGVQDISVIPPEQQLQLGTSPTAFQGMLTGSGRACEESTWAFGGFGPYQTGRELVDPEGETAWLPADYDDTRYGWVRDPGWKLGECLWAQHGVWDPSSDKLLRKDYFAKNPQTGEPLNYDKFTNTYFMEHYRAYRDALRSVWPEAIIFCQPPVMEVPPDLKGTVDDDPNMVHAVHYYDGITLLTKHWNRLYNVDVIGVLRGKYLTPAFAVKIGETAIRNCLRDQLKFLRDESLRYMGTHPLIFTEIGIPFDMDDRHAYKTGDYSGQVSAMDANHFAIEGSTANGFTLWLYTTSNNHEWGDNWNGEDLSIYSVDDLELPSGKLLAFENESQRDPQSPAYSESQRNTESYRVGPRDLKQALQAPSISSEISQSSQDKLGFRAAEAWVRPSPIITNGQILQYGFDLKSCVFSMRLLGEKKGLGQEAATEIFLPDFHFPDTHTVVAVSAGEWTIDYPEIHSVKFQRLRWWHPEGDHNIKIQGVKRKPGDPTVSGEELSYLEQCQGGGCSVM
What is the function of this protein?
Specifically hydrolyzes the glucosidic linkage in glucosylceramide (PubMed:22072709).  May prevent accumulation of aberrent glucosylceramide containing immature ceramide (By similarity).
What are the official names of this protein?
Glucosylceramidase, Endoglycoceramidase-related protein 1, EGCrP1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: RL13_COXB1
Sequence: MATYMANAKTVSPRWLLVNAEGKTLGRLASRIAAILRGKHKAEFTPHVDAGDFVVVINVDKLKVTGNKTQDKQYHHHSGYPGGLKTINFADLQAKKPQRILELAIKGMLPKGPLGRQLYRKLKIYAGDQHPHQAQQPELIDL
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: SFSA_CLOK1
Sequence: MIFHKNIVKAEFIRRPNRFQAYVKLNGSEVMVHVPNTGRCREILLPETTILLREENGINRKTKYDLIAGYKENKLINIDSQIPNKVVEEALENRKISYFTKYNKIEREKTFGNSRFDFKLSGDENLKCYVEVKGVTLEKEGVAMFPDAPTERGRKHLLELIEVKKSGMDAAVLFLIQMKDVKYFRPHDEMDKKFGEALRHAKENYVQVVAYDCDVGENFIILRDEIKVQL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: MRS4_YEAST
Sequence: MNTSELSIAEEIDYEALPSHAPLHSQLLAGAFAGIMEHSLMFPIDALKTRVQAAGLNKAASTGMISQISKISTMEGSMALWKGVQSVILGAGPAHAVYFGTYEFCKARLISPEDMQTHQPMKTALSGTIATIAADALMNPFDTVKQRLQLDTNLRVWNVTKQIYQNEGFAAFYYSYPTTLAMNIPFAAFNFMIYESASKFFNPQNSYNPLIHCLCGGISGATCAALTTPLDCIKTVLQVRGSETVSIEIMKDANTFGRASRAILEVHGWKGFWRGLKPRIVANIPATAISWTAYECAKHFLMKN
What is the function of this protein?
MRS4 suppresses a mitochondrial splice defect in the first intron of the COB gene.  It may act as a carrier, exerting its suppressor activity via modulation of solute concentrations in the mitochondrion (possibly of cations).  Not essential.
What are the official names of this protein?
Mitochondrial RNA-splicing protein MRS4.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.