PharMolix/UniProtQA huggingface dataset:
Protein: SNU13_ASHGO
Sequence: MSSTPNPKAFPLADAALTQQILDVVQQASNMRQLKKGANEATKTLNRGISEFIIMAADCEPIEILLHLPLLCEDKNVPYVFVPSRVALGRACGVSRPVIAASITTNDASAIKSQIYAVKDKIETLLI
What is the function of this protein?
Common component of the spliceosome and rRNA processing machinery.  In association with the spliceosomal U4/U6. U5 tri-snRNP particle, required for splicing of pre-mRNA.  In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs.  Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
What are the official names of this protein?
13 kDa ribonucleoprotein-associated protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CYB_MYOLE
Sequence: MTNIRKSHPLIKIVNSSFIDLPAPSNISSWWNFGSLLGICLALQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWILRYLHANGASMFFICLYLHVGRGLHYGSYMYTETWNIGVTPLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLAEWIWGGFSVDKATLT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CP3AT_PIG
Sequence: MDLIPGFSTETWVLLATSLVLLYLYGTYSHGLFKKLGIPGPRPLPYFGNILGYRKGVDHFDKKCFQQYGKMWGVYDGRQPLLAVTDPNMIKSVLVKECYSVFTNRRSFGPLGAMRNALSLAEDEEWKRIRTLLSPTFTSGKLKEMFPIISHYGDLLVSNLRKEAEKGKPVTMKDIFGAYSMDVITSTAFGVNIDSLNNPQDPFVENSKKLLKFSFFDPFLLSLIFFPFLTPIFEVLNITLFPKSSVNFFTKSVKRMKESRLTDQQKRRVDLLQLMINSQNSKEMDPHKSLSNEELVAQGIIFIFAGYETTSSALSLLAYELATHPDVQQKLQEEIEATFPNKAPPTYDALAQMEYLDMVVNETLRLYPIAARLERACKKDVEIHGVFVPKGTVVVVPVFVLHRDPDLWPEPEEFRPERFSKKHKDTINPYTYLPFGTGPRNCIGMRFALMNMKLALVRVLQNFSFKPCKETQIPLKLTTQGLTQPEKPVVLKILPRDGTVSGA
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 3A29, CYPIIIA29.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: PCS1N_MOUSE
Sequence: MAGSPLLCGPRAGGVGILVLLLLGLLRLPPTLSARPVKEPRSLSAASAPLVETSTPLRLRRAVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRAWGSPRASDPPLAPDDDPDAPAAQLARALLRARLDPAALAAQLVPAPAAAPRPRPPVYDDGPTGPDVEDAGDETPDVDPELLRYLLGRILTGSSEPEAAPAPRRLRRSVDQDLGPEVPPENVLGALLRVKRLENPSPQAPARRLLPP
What is the function of this protein?
Endogenous ligand for GPR171.  Neuropeptide involved in the regulation of feeding.
What are the official names of this protein?
ProSAAS, IA-4, Proprotein convertase subtilisin/kexin type 1 inhibitor, Proprotein convertase 1 inhibitor, pro-SAAS.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus, trans-Golgi network.
Protein: HBG1_CEBAL
Sequence: MSNFTAEDKAAITSLWAKVNVEDAGGETLGRLLVVYPWTQRFFDSFGSLSSPSAIMGNPKVKAHGAKVLTSLGEAIKNLDDLKGTFGQLSELHCDKLHVDPENFRLLGNVLVTVLAVHHGKEFTPEVQASWQKMVAGVASALGSRYH
What is the function of this protein?
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
What are the official names of this protein?
Hemoglobin subunit gamma-1, Gamma-1-globin, Hemoglobin gamma-1 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL37A_METS3
Sequence: MARTKKVGITGRFGARYGRKAKRSVKMIEENMKKNHVCPRCDRPYVKRQAAGIWKCRKCGAVFTGGAYVPETPMAKSAARNIRNVNVEE
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: RL17_SINFN
Sequence: MRHGKAGRKLNRTASHRKAMFANMAASLIEHEQIVTTLPKAKEIRPIVEKLVTLGKRGDLHARRQAISQIRDVAVVSKLFDAIASRYATRNGGYLRIMKAGFRQGDNAPLAVIEFVDRDVDAKGAKDRARVAAEAEAAEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RBM34_HUMAN
Sequence: MALEGMSKRKRKRSVQEGENPDDGVRGSPPEDYRLGQVASSLFRGEHHSRGGTGRLASLFSSLEPQIQPVYVPVPKQTIKKTKRNEEEESTSQIERPLSQEPAKKVKAKKKHTNAEKKLADRESALASADLEEEIHQKQGQKRKNSQPGVKVADRKILDDTEDTVVSQRKKIQINQEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQIESVRFRSLIPAEGTLSKKLAAIKRKIHPDQKNINAYVVFKEESAATQALKRNGAQIADGFRIRVDLASETSSRDKRSVFVGNLPYKVEESAIEKHFLDCGSIMAVRIVRDKMTGIGKGFGYVLFENTDSVHLALKLNNSELMGRKLRVMRSVNKEKFKQQNSNPRLKNVSKPKQGLNFTSKTAEGHPKSLFIGEKAVLLKTKKKGQKKSGRPKKQRKQK
What are the official names of this protein?
RNA-binding protein 34, RNA-binding motif protein 34.
What is the protein family that this protein belongs to?
Belongs to the RRM RBM34 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PSAJ_HELAN
Sequence: MRDLKTYLSVAPVLSTLWFGALAGLLIEINRFFPDALTFPFF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ISPD_BIFLO
Sequence: MTERDFDTPVETPTVQPAPAQGAKPAQTVPVVAVVLAAGFGTRFDPDNPKQLVSVGGKPIVCWSIDAFEHCDRVSDIVVVVNPKVRGEVETLVGEMGYTKVRVIIDGGDERVDSTATALDMLATAGIPDDAKILIHDAVRPFVEQSAIDGSIDALDQFTAATVAYASTDTVLLTEDLGDLKVVKSVPDRPNTFRAQTPQSFRFATIRHAYDLAAADPDFHPTDDTRVVVDYLPDEPVAIVSGAETNLKITTLEDIPTAERIAEEILGRDPKEEARARMHALLAQAAGQMHR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: IAA34_ARATH
Sequence: MYCSDPPHPLHLVASDKQQKDHKLILSWKKPTMDSDPLGVFPNSPKYHPYYSQTTEFGGVIDLGLSLRTIQHEIYHSSGQRYCSNEGYRRKWGYVKVTMDGLVVGRKVCVLDHGSYSTLAHQLEDMFGMQSVSGLRLFQMESEFCLVYRDEEGLWRNAGDVPWNEFIESVERLRITRRNDAVLPF
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Auxin-responsive protein IAA34, Indoleacetic acid-induced protein 34.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENV_AVIRE
Sequence: MDCLTDLRSTEGKVDQAGKTLILLVVWWGFGTTAEGHPLQQLWELPCDCSGGYVSPDLPITPTPSIAVASPLPDLRVWLQGSWGWGGGFRQQWECVFKPKIIPSVQEQPGPCECLTIATQMHSTCYEKAQECTLLGKTYFTAILQKTKLGSYEDGPNKLLQASCTGIWETSMLGPRCPCVCLDGGGPTDRFGRICAEGLEEIIRHSYPSVQYHPLALPRPRGVDLDPQTSDILEATHQVLNATNPQLAENCWLCMTLGTQSPQPSRRMAMSLSMEIAVLASLSGATHRVNRCQLLCREADNRTGIPVGYVHFTNCTSIQESLTRRVIYEILRDYVLHRVMYLCVEQHAYTALPNKWIGLCILASIVPDMSIIPGEEPIPLPSIEYTAGRHKRAVQFIPLLVGLGITGATLAGGTGLGVSVHTYHKLSNQLIEDVQALSGTINDLQDQIDSLAEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKSGIVRDKIRKLQEDLLARKRALYDNPLWNGLNGFLPYLLPSLGPLFGLILFLTLGPCIRKTLTRIIHDKIQGSKNPRISPAVQATPNRDGYPRSMV
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N- terminus of Gag (By similarity).
Protein: Y634_MYCPN
Sequence: MQNTNRKILWTSNESSDIAAPAYQTWAQEEGYEIISIGSSQYQSMENDAEFKSYTLNDFGDRFVNEFQTEEVPFHKLTEIEKDNWNWVMAKVKELTRVWSNWKNLYKHYEFSIIKKHPNAEGLHSNGRIQIVRKILNERSHLFNTIMHEICHATSFSPDVSQRFEQGLTSAFYPVMKLKPE
What are the official names of this protein?
Uncharacterized protein MPN_634.
What is the protein family that this protein belongs to?
To M.pneumoniae MPN_635 C-terminal region.
Protein: CCNY_HUMAN
Sequence: MGNTTSCCVSSSPKLRRNAHSRLESYRPDTDLSREDTGCNLQHISDRENIDDLNMEFNPSDHPRASTIFLSKSQTDVREKRKSLFINHHPPGQIARKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIYYHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRERAHKLEAISRLCEDKYKDLRRSARKRSASADNLTLPRWSPAIIS
What is the function of this protein?
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16.  Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway.  Recruits CDK16 to the plasma membrane.  Isoform 3 might play a role in the activation of MYC-mediated transcription.
What are the official names of this protein?
Cyclin-Y, Cyc-Y, Cyclin box protein 1, Cyclin fold protein 1, cyclin-X.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin Y subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus.
Protein: RL30_DESAL
Sequence: MKQKIKVTLVKSMIARPEKHRKVLRGMGLTKLNKTVELEDTPCIRGMIHKVSHLVSVKE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: C555A_DICDI
Sequence: MIIIVIVVFLFYFSFLNLNLNPKKKRPPSPITLPVIGNLISLLNNQPQNILFNYYKKYGKIYQLQYGIVNTVVLSEFDILKEAFIENGEVFIERYNKITKKFKSSENIVNSNGLIWKKLQSISIQELSPNIKIKKYEPMIINETNKLIDSFNEHIKSNESIDPTLNIKICFLNIIISFLFNFRYNDYKDEKVIQLVDYIHSIFRMGSHPIPQDYIPILNKFYINKTTKIHQKIFENIYEYIENQVQKRLEILNKNNNNNNNNINECFVDLLLLKFKSNLLTWNEVIKTTTDLMIAGSDTNSLFTIHLIIALTNRENIQNKVFNEILNFYILNENNKITFSNKSKTPYYNSVLKEVERRFTVSPLSQPHRTNKDIILNGYFIPSGSQIIQNVYSCHLNDKDWENPFQFNPDRFLNNNQLEKKLITFGMGPRNCLGFQFALMSIWIVNLILFKSIKFSSNKLIEEEIREGGTTLSPFPFKINLIKR
What are the official names of this protein?
Probable cytochrome P450 555A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MOAA_TRIV2
Sequence: MNQVDYLRISLIDRCNFRCQYCMPEGSELDYILKQQLLTDEELLTLVQEVFIPVGFRQFRLTGGEPLLRPRVVDLVGAIASLPQTQDLSMTTNGFLLAPIAQNLYDAGLRRINISLDSLDPHIFDQIIGSHGRSRWQQVWDGIQAAHRVGFDPLKLNVVVIPGVNDHEILDLAALTIDKQWHVRFIEFMPIGNGELFGDRGWVSSSQLRQQIRDRWGLTDAQVRGSGPADVFQIPGAKGTLGFISQMSECFCDRCNRMRLSADGWLRPCLLNETGQLDLKTSLRSGVSIHQLREQVRHLLAIKPEINYKGRDSGTTGAYSRTMSQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RLMG_ECO24
Sequence: MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRMNVETNMPEALDRCEFMINNALSGVKPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKTVKLGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOT_PSEAE
Sequence: MHIQSSQQNPSFVAELSQAVAGRLGQVEARQVATPREAQQLAQRQEAPKGEGLLSRLGAALARPFVAIIEWLGKLLGSRAHAATQAPLSRQDAPPAASLSAAEIKQMMLQKALPLTLGGLGKASELATLTAERLAKDHTRLASGDGALRSLATALVGIRDGSRIEASRTQAARLLEQSVGGIALQQWGTAGGAASQHVLSASPEQLREIAVQLHAVMDKVALLRHAVESEVKGEPVDKALADGLVEHFGLEAEQYLGEHPDGPYSDAEVMALGLYTNGEYQHLNRSLRQGRELDAGQALIDRGMSAAFEKSGPAEQVVKTFRGTQGRDAFEAVKEGQVGHDAGYLSTSRDPGVARSFAGQGTITTLFGRSGIDVSEISIEGDEQEILYDKGTDMRVLLSAKDGQGVTRRVLEEATLGERSGHGEGLLDALDLATGTDRSGKPQEQDLRLRMRGLDLA
What is the function of this protein?
Bifunctional effector protein that is secreted and delivered by the type III secretion system into eukaryotic target cells.  The N-terminus encodes a GTPase-activating protein activity, whereas the C-terminus encodes an ADP-ribosyltransferase activity (PubMed:11298647).  ADP-ribosylates several eukaryotic proteins including CT10 regulator of kinase (Crk) proteins (PubMed:12807879).  In turn, induces atypical anoikis apoptosis by transforming Crk adaptor protein into a cytotoxin (PubMed:26020630).  Affects host cell morphology by disrupting the actin cytoskeleton (PubMed:14688136).  In addition to this activity, acts via its N-terminal region as a GTPase-activating protein (GAP) for host Rho GTPases including RhoA, Rac1, Cdc42 and Ras (PubMed:11895987).  The GAP domain activity induces mitochondrial disruption in the target host cell by activating host caspases 3 and 9 that execute cellular death (PubMed:26451042).  This activity also causes stress fiber disassembly (PubMed:11895987).
What are the official names of this protein?
Exoenzyme T.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the Arg-specific ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via type III secretion system (T3SS) and delivered into the host cytoplasm.
Protein: RNH_BAUCH
Sequence: MRKKIEIFTDGSCFGNPGPGGYGAILRYKKYEKEHSAGFLLTTNNRMELMAAIIALEFLRDPCEAIVYIDSKYVHQGVIQWIYNWKKHNWKNSAKKIIKNLDLWQRLDVVSNLHVIHWRWVKSHTGHPENERCDELARIAAEHPKFEDIGYKR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBL_ECOLI
Sequence: MNFQQLKIIREAARQDYNLTEVANMLFTSQSGVSRHIRELEDELGIEIFVRRGKRLLGMTEPGKALLVIAERILNEASNVRRLADLFTNDTSGVLTIATTHTQARYSLPEVIKAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIASERLSNDPQLVAFPWFRWHHSLLVPHDHPLTQISPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLLADIVLSAQDSDVIKTYVALGLGIGLVAEQSSGEQEEENLIRLDTRHLFDANTVWLGLKRGQLQRNYVWRFLELCNAGLSVEDIKRQVMESSEEEIDYQI
What is the function of this protein?
May be an accessory regulatory protein within the cys regulon.
What are the official names of this protein?
HTH-type transcriptional regulator cbl.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RIPT_POLML
Sequence: MRVVAGILYIVVMAICGLGIQGGTLQDYPSVYFQDSTLQQDFPTIFFNILAGETYGDFIADLREIVTRTADTKNGSIPVLLNPAHPVPVRERFVKVHLTGRNGKTVILALDVTNLYVAAFSANNVAYFFRDFSALERENLFSGMLTIRLSFTSNYVSLEHKAGVGRENISLGPTPLDEACTKSLWSGTTVTEASIAKALLVVIQMVSEAARFRHIEERVRRSFTAADHDQLTFRPDGLMLSMENEWPSMSLEVQRSIEGGIFIGVVQLQDESFQPLRVDNFNTLSRYTMVALLLFRCGHPRATAGTSSTTPAAAQIIRMPVDVLAGEEYYDEETCTVGEPTRRISGLDGLCMDVRNESNNDGIPIQLWPCGAQRNQQWTFHTDGTIQSMGKCMTSNGYHPGDYVMIFNCSTAPVPDATKWVVSIDGSITNPHSGLVLTAPQAAQTTILLVVRNTHSAKQGRSVGDDVEPIVTYIVGFKYMCLQGNNENNTRVWLEDCAVDRPQQWWALYSDGTIRVDSDRSLCVTSDGHSSRDAIIILTCDGGINQRLVFNTDGTILNPNAQLVMDVRQSNVALRQIILYQPTGNPNQQWMTMITRTRPSLTS
What is the function of this protein?
GalNAc-specific agglutinin.  Behaves as a type-2 ribosome-inactivating protein.  Inhibits mammalian ribosomes (PubMed:10785398).  The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA (Probable).  The B chain binds to cell receptors and probably facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (lectin activity) (Probable).  Involved in plant defense against insects (By similarity).  Has very low cytotoxic activity against the human tumor cell lines CEM and Molt4 (PubMed:10785398).
What are the official names of this protein?
Ribosome-inactivating protein PMRIPt.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 2 RIP subfamily.
Protein: DEOC_SYNP2
Sequence: MAIPANEIDLARYLEHSLLHPAATEAQVKECCEAAVQFDFPAVCLYPTAIKTARDFLHQRPIQICSVVGFPAGAHTTATKLYEAQEAVENGATELDVMLNLAFVKMGESEKLYQEVAQIVELTKVPIKGILETALLTDTEKRLAAEICLDAGVSYLKTSTGWFGGTTVADVKLLYGITKGRIGIKAAGGIKTVDQAIALIQAGATRLGTSRSIKIMQEREQVSDNPTW
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2823_SHEON
Sequence: MITCLIVDDELFAREELADSLSQEADIEIIGQCSNAIEALQTITKEKPQLVFLDIQMPRISGMELIAMLDPDTLPKIVFVTAFDEFAVKAFDNHAFDYLLKPIDADRLSKTLKRVRKDLTPQAVNLIAPRSLEHLPCYSGSKLKVIPIQDVEYVFSDLSGIHVACTKGKVHTQLTLKVLEEKTPLVHCHRQYLISPKAIAEIELLDTGAEVTTLLGDKVPVSRRYLKSLKQLFGFQ
What are the official names of this protein?
Uncharacterized response regulatory protein SO_2823.
Protein: COX10_MOUSE
Sequence: MAASPHTISSRLLTGSVGGCIWYLERRAIQGLPHRVTRLFRNVSNQWVTLQHLSFLKRMYVTQLHRGLSQRVKPKPEPPASPFLEHTSSGQARADEDELPSFPAPSRPLSRKPNEELVELEATSIVDHSLDTAKEKKEERQWKEMKLHTDDLPGILARLSKIKLTALVVSTTSAGFALAPGPFDWSCFLLTSLGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVALLTWGVNPLTGALGVFNIFLYTCCYTPLKRVSITNTWVGAVVGAIPPVMGWTAATGSLDAGALLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPALCRRVALRHCLALIALSTAAPVLDITTWVFPVISLPINLYISYLGFRFYVDADRRSSRKLFFCSLWHLPLLLLLMLTCKQRPGQEGDKGEAPS
What is the function of this protein?
Converts protoheme IX and farnesyl diphosphate to heme O.
What are the official names of this protein?
Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: HIS4_BACCQ
Sequence: MEIFPAIDLKEGRCVRLYQGEFSKETVMNEDPVAQAIIFETFGAKRLHIVDLDGAVAGESLNLSVIERICKAVRIPVQVGGGIRSLVSVEKLFSVGVDKVILGTAALYDKPFLEETVRLYKEKIIVGIDAKNGFVATRGWLDVSEISYIDLAKQMEKIGVQTIVFTDISKDGTLAGPNVEQLELLQKNVATRVIASGGIASIQDVKKLNDMNIYGVIIGKALYEKTIDLEEVLEVTKLC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_RHILW
Sequence: MKFLDEAKVYIRSGDGGGGSVSFRREKFIEFGGPDGGDGGRGGDVWVETVNGLNTLIDFRFQQHFKATIGTHGMGRNRTGANGSDVTLKVPVGTQIFEEDRETLICDLTVEGQRYCLAHGGNGGFGNAHFKTSTNQAPDWANPGLPGEEKTLWLRLKLIADAGLVGMPNAGKSTFLASVTRARPKIANYPFTTLHPNLGVATIDEREFILADIPGLIEGAHEGVGIGDRFLGHVERTRVLLHLVSAQEEKVGKAYKTVKHELEAYGNELTDKPEIVALSQIDVLDEAELKKKTKELAKACGKTPFQISAVTGKGMTEVLRALRDIIVEENAEEKPAKVPKQRHRDIVVADEGEDVGEDGADDQP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CR8CA_BACTP
Sequence: MSPNNQNEYEIIDALSPTSVSDNSIRYPLANDQTNTLQNMNYKDYLKMTESTNAELSRNPGTFISAQDAVGTGIDIVSTIISGLGIPVLGEVFSILGSLIGLLWPSNNENVWQIFMNRVEELIDQKILDSVRSRAIADLANSRIAVEYYQNALEDWRKNPHSTRSAALVKERFGNAEAILRTNMGSFSQTNYETPLLPTYAQAASLHLLVMRDVQIYGKEWGYPQNDIDLFYKEQVSYTARYSDHCVQWYNAGLNKLRGTGAKQWVDYNRFRREMNVMVLDLVALFPNYDARIYPLETNAELTREIFTDPVGSYVTGQSSTLISWYDMIPAALPSFSTLENLLRKPDFFTLLQEIRMYTSFRQNGTIEYYNYWGGQRLTLSYIYGSSFNKYSGVLAGAEDIIPVGQNDIYRVVWTYIGRYTNSLLGVNPVTFYFSNNTQKTYSKPKQFAGGIKTIDSGEELTYENYQSYSHRVSYITSFEIKSTGGTVLGVVPIFGWTHSSASRNNFIYATKISQIPINKASRTSGGAVWNFQEGLYNGGPVMKLSGSGSQVINLRVATDAKGASQRYRIRIRYASDRAGKFTISSRSPENPATYSASIAYTNTMSTNASLTYSTFAYAESGPINLGISGSSRTFDISITKEAGAANLYIDRIEFIPVNTLFEAEEDLDVAKKAVNGLFTNEKDALQTSVTDYQVNQAANLIECLSDELYPNEKRMLWDAVKEAKRLVQARNLLQDTGFNRINGENGWTGSTGIEVVEGDVLFKDRSLRLTSAREIDTETYPTYLYQQIDESLLKPYTRYKLKGFIGSSQDLEIKLIRHRANQIVKNVPDNLLPDVRPVNSCGGVDRCSEQQYVDANLALENNGENGNMSSDSHAFSFHIDTGEIDLNENTGIWIVFKIPTTNGNATLGNLEFVEEGPLSGETLEWAQQQEQQWQDKMARKRAASEKTYYAAKQAIDRLFADYQDQKLNSGVEMSDLLAAQNLVQSIPYVYNDALPEIPGMNYTSFTELTNRLQQAWNLYDLQNAIPNGDFRNGLSNWNATSDVNVQQLSDTSVLVIPNWNSQVSQQFTVQPNYRYVLRVTARKEGVGDGYVIIRDGANQTETLTFNICDDDTGVLSTDQTSYITKTVEFTPSTEQVWIDMSETEGVFNIESVELVLEEE
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects.  Active on various scarabaeid beetles such as Anomala cuprea, A. rufocuprea and Popillia japonica.
What are the official names of this protein?
Pesticidal crystal protein Cry8Ca, 130 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryVIIIC(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.