Protein: POLG_CSFVA
Sequence: MELNHFELLYKTSKQKPVGVEEPVYDTAGRPLFGNPSEVHPQSTLKLPHDRGRGDIRTTLRDLPRKGDCRSGNHLGPVSGIYIKPGPVYYQDYTGPVYHRAPLEFFDEAQFCEVTKRIGRVTGSDGKLYHIYVCVDGCILLKLAKRGTPRTLKWIRNFTNCPLWVTSCSDDGASGSKDKKPDRMNKGKLKIAPREHEKDSKTKPPDATIVVEGVKYQIKKKGKVKGKNTQDGLYHNKNKPPESRKKLEKALLAWAVITILLYQPVAAENITQWNLSDNGTNGIQRAMYLRGVNRSLHGIWPEKICKGVPTHLATDTELKEIRGMMDASERTNYTCCRLQRHEWNKHGWCNWYNIDPWIQLMNRTQTNLTEGPPDKECAVTCRYDKNTDVNVVTQARNRPTTLTGCKKGKNFSFAGTVIEGPCNFNVSVEDILYGDHECGSLLQDTALYLLDGMTNTIENARQGAARVTSWLGRQLSTAGKKLERRSKTWFGAYALSPYCNVTRKIGYIWYTNNCTPACLPKNTKIIGPGKFDTNAEDGKILHEMGGHLSEFLLLSLVILSDFAPETASTLYLILHYAIPQSHEEPEGCDTNQLNLTVKLRTEDVVPSSVWNIGKYVCVRPDWWPYETKVALLFEEAGQVIKLVLRALRDLTRVWNSASTTAFLICLIKVLRGQVVQGIIWLLLVTGAQGRLACKEDYRYAISSTNEIGLLGAEGLTTTWKEYSHGLQLDDGTVKAVCTAGSFKVTALNVVSRRYLASLHKRALPTSVTFELLFDGTNPAIEEMDDDFGFGLCPFDTSPVIKGKYNTTLLNGSAFYLVCPIGWTGVVECTAVSPTTLRTEVVKTFRRDKPFPHRVDCVTTIVEKEDLFHCKLGGNWTCVKGDPVTYKGGQVKQCRWCGFEFKEPYGLPHYPIGKCILTNETGYRVVDSTDCNRDGVVISTEGEHECLIGNTTVKVHALDERLGPMPCRPKEIVSSEGPVRKTSCTFNYTKTLRNKYYEPRDSYFQQYMLKGEYQYWFNLDVTDHHTDYFAEFVVLVVVALLGGRYVLWLIVTYIILTEQLAAGLQLGQGEVVLIGNLITHTDNEVVVYFLLLYLVIRDEPIKKWILLLFHAMTNNPVKTITVALLMISGVAKGGKIDGGWQRQPVTSFDIQLALAVVVVVVMLLAKRDPTTFPLVITVATLRTAKITNGFSTDLVIATVSAALLTWTYISDYYKYKTWLQYLVSTVTGIFLIRVLKGIGELDLHAPTLPSHRPLFYILVYLISTAVVTRWNLDVAGLLLQCVPTLLMVFTMWADILTLILILPTYELTKLYYLKEVKIGAERGWLWKTNYKRVNDIYEVDQTSEGVYLFPSKQRTSAITSTMLPLIKAILISCISNKWQLIYLLYLIFEVSYYLHKKVIDEIAGGTNFVSRLVAALIEVNWAFDNEEVKGLKKFFLLSSRVKELIIKHKVRNEVVVRWFGDEEIYGMPKLIGLVKAATLSRNKHCMLCTVCEDRDWRGETCPKCGRFGPPVVCGMTLADFEEKHYKRIFIREDQSGGPLREEHAGYLQYKARGQLFLRNLPVLATKVKMLLVGNLGTEIGDLEHLGWVLRGPAVCKKVTEHERCTTSIMDKLTAFFGVMPRGTTPRAPVRFPTSLLKIRRGLETGWAYTHQGGISSVDHVTCGKDLLVCDTMGRTRVVCQSNNKMTDESEYGVKTDSGCPEGARCYVFNPEAVNISGTKGAMVHLQKTGGEFTCVTASGTPAFFDLKNLKGWSGLPIFEASSGRVVGRVKVGKNEDSKPTKLMSGIQTVSKSATDLTEMVKKITTMNRGEFRQITLATGAGKTTELPRSVIEEIGRHKRVLVLIPLRAAAESVYQYMRQKHPSIAFNLRIGEMKEGDMATGITYASYGYFCQMSQPKLRAAMVEYSFIFLDEYHCATPEQLAIMGKIHRFSENLRVVAMTATPAGTVTTTGQKHPIEEFIAPEVMKGEDLGSEYLDIAGLKIPVEEMKNNMLVFVPTRNMAVEAAKKLKAKGYNSGYYYSGEDPSNLRVVTSQSPYVVVATNAIESGVTLPDLDVVVDTGLKCEKRIRLSPKMPFIVTGLKRMAVTIGEQAQRRGRVGRVKPGRYYRSQETPVGSKDYHYDLLQAQRYGIEDGINITKSFREMNYDWSLYEEDSLMITQLEILNNLLISEELPMAVKNIMARTDHPEPIQLAYNSYETQVPVLFPKIRNGEVTDTYDNYTFLNARKLGDDVPPYVYATEDEDLAVELLGLDWPDPGNQGTVEAGRALKQVVGLSTAENALLVALFGYVGYQALSKRHIPVVTDIYSVEDHRLEDTTHLQYAPNAIKTEGKETELKELAQGDVQRCVEAVTNYAREGIQFMKSQALKVRETPTYKETMNTVADYVKKFIEALTDSKEDIIKYGLWGAHTALYKSIGARLGHETAFATLVVKWLAFGGESISDHIKQAATDLVVYYIINRPQFPGDTETQQEGRKFVASLLVSALATYTYKSWNYNNLSKIVEPALATLPYAAKALKLFAPTRLESVVILSTAIYKTYLSIRRGKSDGLLGTGVSAAMEIMSQNPVSVGIAVMLGVGAVAAHNAIEASEQKRTLLMKVFVKNFLDQAATDELVKESPEKIIMALFEAVQTVGNPLRLVYHLYGVFYKGWEAKELAQRTAGRNLFTLIMFEAVELLGVDSEGKIRQLSSNYILELLYKFRDNIKSSVREIAISWAPAPFSCDWTPTDDRIGLPHENYLRVETKCPCGYRMKAVKNCAGELRLLEEGGSFLCRNKFGRGSQNYRVTKYYDDNLSEIKPVIRMEGHVELYYKGATIKLDFNNSKTVLATDKWEVDHSTLVRALKRYTGAGYRGAYLGEKPNHKHLIQRDCATITKDKVCFIKMKRGCAFTYDLSLHNLTRLIELVHKNNLEDREIPAVTVTTWLAYTFVNEDIGTIKPTFGEKVTPEKQEEVVLQPAVVVDTTDVAVTVVGETSTMTTGETPTTFTSLGSDSKVRQVLKLGVDDGQYPGPNQQRASLLEAIQGVDERPSVLILGSDKATSNRVKTAKNVKIYRSRDPLELREMMKRGKILVVALSRVDTALLKFVDYKGTFLTRETLEALSLGKPKKRDITKAEAQWLLRLEDQIEELPDWFAAKEPIFLEANIKRDKYHLVGDIATIKEKAKQLGATDSTKISKEVGAKVYSMKLSNWVIQEENKQGSLAPLFEELLQQCPPGGQNKTTHMVSAYQLAQGNWVPVSCHVFMGTIPARRTKTHPYEAYVKLRELVDEHKMKALCGGSGLSKHNEWVIGKVKYQGNLRTKHMLNPGKVAEQLHREGYRHNVYNKTIGSVMTATGIRLEKLPVVRAQTDTTNFHQAIRDKIDKEENLQTPGLHKKLMEVFNALKRPELEASYDAVDWEELERGINRKGAAGFFERKNIGEVLDSEKNKVEEVIDSLKKGRNIRYYETAIPKNEKRDVNDDWTAGDFVDEKKPRVIQYPEAKTRLAITKVMYKWVKQKPVVIPGYEGKTPLFQIFDKVKKEWDQFQNPVAVSFDTKAWDTQVTTRDLELIRDIQKFYFKKKWHKFIDTLTKHMSEVPVISADGEVYIRKGQRGSGQPDTSAGNSMLNVLTMVYAFCEATGVPYKSFDRVAKIHVCGDDGFLITERALGEKFASKGVQILYEAGKPQKITEGDKMKVAYQFDDIEFCSHTPVQVRWSDNTSSYMPGRNTTTILAKMATRLDSSGERGTIAYEKAVAFSFLLMYSWNPLIRRICLLVLSTELQVRPGKSTTYYYEGDPISAYKEVIGHNLFDLKRTSFEKLAKLNLSMSTLGVWTRHTSKRLLQDCVNVGTKEGNWLVNADRLVSSKTGNRYIPGEGHTLQGKHYEELILARKPIGNFEGTDRYNLGPIVNVVLRRLKIMMMALIGRGV
What is the function of this protein?
Replicates the viral (+) and (-) genome.
What are the official names of this protein?
Genome polyprotein.
What is the protein family that this protein belongs to?
Belongs to the pestivirus polyprotein family.
What are the subcellular locations of this protein?
[N-terminal protease]: Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein C]: Virion. SUBCELLULAR LOCATION: [E(rns) glycoprotein]: Host cell membrane; Peripheral membrane protein. Virion membrane; Peripheral membrane protein. Note=The C-terminus membrane anchor of Erns represents an amphipathic helix embedded in plane into the membrane. SUBCELLULAR LOCATION: [Envelope glycoprotein E2]: Host cell surface. Virion membrane. SUBCELLULAR LOCATION: [Cysteine protease NS2]: Host membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Serine protease NS3]: Host cytoplasm. SUBCELLULAR LOCATION: [Non-structural protein 4B]: Host cytoplasm. SUBCELLULAR LOCATION: [Non-structural protein 5A]: Host cytoplasm.