PharMolix/UniProtQA huggingface dataset:
Protein: 3L2A_BUNCA
Sequence: MKTLLLTLVVVTIVCLDLGYTIVCHTTATSPISAVTCPPGENLCYRKMWCDAFCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNPHPKQRPG
What is the function of this protein?
Binds with high affinity to muscular (tested on Torpedo marmorata, Kd=0. 4 nM) and neuronal (tested on chimeric alpha-7/CHRNA7, Kd=0. 95 nM) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.  It also shows an activity on GABA(A) receptors.  It antagonises GABA-activated currents with high potency when tested on primary hippocampal neurons.  It inhibits recombinantly expressed GABA(A) receptors composed of alpha-2-beta-2-gamma-2 (GABRA2-GABRB2-GABRG2) subunits with high potency (62. 3% inhibition at 20 uM of toxin).  It also shows a weaker inhibition on GABA(A) receptors composed of alpha-1-beta-2-gamma-2 (GABRA1-GABRB2-GABRG2) subunits, alpha-4-beta-2-gamma-2 (GABRA4-GABRB2-GABRG2) subunits, and alpha-5-beta-2-gamma-2 (GABRA5-GABRB2-GABRG2) subunits.  A very weak inhibition is also observed on GABA(A) receptor composed of alpha-1-beta-3-gamma-2 (GABRA1-GABRB3-GABRG2).  It has also been shown to bind and inhibit recombinant GABA(A) receptor beta-3/GABRB3 subunit (Kd=about 50 nM).  In addition, it blocks the extracellular increase of dopamine evoked by nicotine only at the higher dose (4. 2 uM).  In vivo, when intraperitoneally injected into mice, induces flaccid paralysis of the limbs and respiratory distress, and causes death in a dose-dependent manner (PubMed:14505938).
What are the official names of this protein?
Alpha-bungarotoxin, isoform A31, Alpha-BgTx (A31), Alpha-bungarotoxin (A31).
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VPC14_MYCTO
Sequence: MTYVLDTNVVSALRVPGRHPAVAAWADSVQVAEQFVVAITLAEIERGVIAKERTDPTQSEHLRRWFDDKVLRIFVFARRGTNLIMQPLAGHIGYSLYSGISWF
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  The cognate antitoxin is VapB14 (By similarity).
What are the official names of this protein?
Ribonuclease VapC14, RNase VapC14, Toxin VapC14.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: IF1_TRIV2
Sequence: MSKQDLIEMEGTVTESLPNAMFRVDLDNGFNVLAHISGKIRRNYIKILPGDRVKVELTPYDLTKGRITYRLRKK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_I000X
Sequence: MDPNTVSSFQVDCFLWHVRKRVADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIKTATRAGKQIVERILKEESDEALKMTMASVPASRYLTDMTLEELSRDWSMLIPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTAEDVKNAVGVLIGGLEWNDNTVRVSETLQRFAWRSSNENGRPPLTPKQKREMAGTIRSEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: RL20_MALP2
Sequence: MRVKTGPTTRRRRKSWLKKAEGAWGINSTSYRNAKQTVMQASKYAYRDRKNKKRDFRKLWIARINAAIRKENYTYSAFMHKLKQKEIAINRKMLSELAIQNPEEFKKFVHSVMLK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MNHB1_STAAN
Sequence: MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit B1, Mnh complex subunit B1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS20_CHESB
Sequence: MANTTSAKKAVRKIARRTAINKTRRSRVRTYVRKVEEAIASGDKGAAEAALKAAQPELMRAATRGVLHKNTAARKVSRLARRVKTLNA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: TGT_BACC0
Sequence: MTAIRYEFIKTCKQTGARLGRVHTPHGSFDTPTFMPVGTLATVKTMSPEELKAMDSGIILSNTYHLWLRPGHEIIREAGGLHKFMNWDRAILTDSGGFQVFSLSDFRRIEEEGVHFRNHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPFPATFEYMKKSVERTSRWAERCLKAHERPQDQGLFGIVQGGEFEELRRQSAKDLVSMDFPGYAVGGLSVGEPKDIMNRVLEFTTPLLPDNKPRYLMGVGSPDSLIDGAIRGIDMFDCVLPTRIARNGTCMTSEGRLVVKNAKFARDFGPLDPNCDCYTCKNYSRAYIRHLMKCDETFGIRLTSYHNLHFLLNLMEQVRQAIREDRLGDFREEFFEQYGFNKPNAKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ATP6_STRPU
Sequence: MTASILGQFFPETLFFIPMNVFSMAFCLSWLVFIYPVNWAPSRFQSIWLGFRSNILEMIFQNTSPNTAPWAGLIAGVFVLILLVNVLGLFPPYAFQSPTSNISLTYSLGFPLWMAINILGFYLAFNSRLSHLVPQGTPSALIPLMVWIETLSLFAQPIALGLRLAANLTAGHLLIFLLSTAIWLLSSSLMISVPILIIFILLFVLEIGVACIQAYVFTALIHFYLQQNI
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RXLT1_DANRE
Sequence: MRFFRRKIAIIVILAYAIFSLYAAYNVFFSKRVISRVHRVVKKGSVIIETGKAGEKEWNPWEEDERAHSVVVQKRRDAFRLYRDQAAKNRPKTYKVQIWGKAAIGLYLWEHILEGSLNPSDKSSQWREGEIQSGKIHFSFYTGPAVVQGHVPPDTDSVVLVLNGREQQKISYSVQWLQHVQSLIQARTISRVAVVLLGNEQCNNNWISPYLKRNGGFVDLLFLVYDSPWVNDKDIFQWPLGVATYRHFPVVTLSSQMVKKDRPYLCNFLGTIYKNSSRESLMNLLKQNNMEKDCLMHAREKWLPQETSDTSRQYQMALAQSDLTLCPVGVNSECYRIYEACAYGSVPVVEDVLTPGACAVGNRSPLRLLKDAGAPFIFLKDWKELPVILERERAMSQKEKTERRMRLLEWYSSFRQQMKDRFTEVLEENFFKIT
What is the function of this protein?
Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O-mannosyl glycan (By similarity).  Participates in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:27130732).
What are the official names of this protein?
Ribitol-5-phosphate xylosyltransferase 1, Transmembrane protein 5, UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TMEM5 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: Y5144_RHILO
Sequence: MAVADDIALIRKQEEVLVFPAFDEAVAFKIGSAIRARAIAENLPIIVDIRLWDRPLFYAAMPGSNASNPDWARRKINVVRRFLRSTYRMVLEQQRPDRAFKIGEGLDVSDYVLAGGGFPVTVKGAGVIGVIAVSGLPEREDHGVVIDALCDHLGIDKRGLVLASEAE
What are the official names of this protein?
UPF0303 protein mlr5144.
What is the protein family that this protein belongs to?
Belongs to the UPF0303 family.
Protein: LON_DESRM
Sequence: MNSEIKSLPLLPLRGILVFPYMVIHLDVGREKSIQAIEEAMVQDRMIFLATQREAQTDEPTVDDIYNIGTVAEVKQLLKLPGGTIRVLVEGIARAKIEKYEHQDPYFRVEVQQYSEEFEKGAEVEALMRSLVYQFEQYVKLSKRIPPETVVSVVNLEEPGRLADIIASHLALKIEDKQNVLESVEIVDRLEKLCGIVAKELEIVELERKINIRVRKQMEKTQKEYYLREQMKAIQKELGEKDERVAECEEFREKISKAKFPKEAEEKALKEVERLEKMPPMAAEAAVVRNYLDWMLSLPWSKSTKDRIDINAAEEVLEADHYGLKDPKERITEYLAIRKLAKKMKGPILCLVGPPGVGKTSLGRSVARALDRKFVRISLGGVRDEAEIRGHRRTYVGAMPGRVIQGMRTAGSKNPVFLLDEIDKMASDFRGDPSSALLEVLDPEQNSTFSDHYIETPFDLSNVMFITTANNMYSIPRPLLDRMEVIQISGYTEEEKLQIAKRHLMPKQIKDHGLTEEMIQISENTILKVIREYTRESGVRNLERKIASICRKTAKKIVAGQAEKVKVTTQNLEQFLGIPRYRYGVAEQNDEVGTVTGMAWTEVGGDTLVIEVTTYKGTGRMTLTGKLGDVMKESAQAGYSFIRSRAQELGIDQEMFEKWDLHIHIPEGAIPKDGPSAGITMATAMASVLTGRKVRHDIAMTGEITLRGRVLPVGGIKEKVMAAHRAGIKLIILPNDNKKDLEDIPVNIKKQLEFKLVDHIDQVLAIALLEKEVVDTTTVLEPEAAVMDNPHFSAVDSQEVQQQGGTQLPS
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUBA_BOMMO
Sequence: MVQDGNPPDDNVFRAFCNALYNTVDAPVTWFRETVVEPNQKKYPWYHQNYRRVPTIDQCYDDDVVCDFEANAQFKRDRAVDSEILSILRQRYEDCMMYEQPDHATKCRSLWDKYKSAEEAWFIKYGDLGAYGDARKAYMKQKHRMVWERRNGPLSDLTK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB10 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y5968_PSEA7
Sequence: MSTQNSAYSAFSSLLAEAALPVSPAELHGHLLGRVCAGAGFDEAAWQHAAAELLGGAPGERLEAALSGLLGMVRQDFSAGEVAVVLLLPDDETPLAQRTEALGQWCQGFLAGFGLTAREGSLTGEAEEVLQDMAAIAQVQGQLEDSEDGETDYMEVMEYLRVAPLLLFAECGKPLEPAPKPSLH
What are the official names of this protein?
UPF0149 protein PSPA7_5968.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: BLA4_KLEPN
Sequence: SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQLQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
What is the function of this protein?
SHV enzymes hydrolyze broad spectrum cephalosporins notably cefotaxime and ceftazidime.  SHV-4 causes particularly high levels of resistance to aztreonam and ceftazidime.
What are the official names of this protein?
Beta-lactamase SHV-4, Ceftazidimase 5, CAZ-5.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: LCBA_NEIME
Sequence: MKRLKKLTREPGVFFRDYFNKKYPVRNIEQRINEIEEPAIIANSLHLAAVESAIHLSPFKIDVVFTWVDNSDTQWQQRHQQYCHAASPNNLYSNDETRFANHNELYYSLHSVRSFLPWVNHIYIITDSQTPKWFKSAEYPNVSIIDHSEIIDKQYLPTFNSHVIEAHLHNIPNLSEHFIYFNDDVFVARPLHREHFFHANGIASLFIADKSLQKMATKGTITPTLSASQNCIRLLNQRYDCNLDHPLVHTYVPLRKSGFQTAWQYYREEIKAFLPNKFRTNQDLNLATFLVPWLMYLDGKSIPNNDICYYFNIRSNKAPTQYLKLLQKNEDNQQPHSFCANDFHSEQQLYDYHAKLIAMLKDYFKI
What are the official names of this protein?
Capsular polysaccharide phosphotransferase LcbA, Stealth protein LcbA.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: SARZ_STAHJ
Sequence: MYIKDSYLSNQLCFLLYVTSKEVIKKYTYYLKKHDLTYTSFMVIMAIENEEKINIKSLGRRVFLDSGTLTPLLKKLEKKGYVQRMREKEDERNLQITLTESGINIKPTLKAISDQVFEDFDISQDEKDNLVNSLKHVISNNFDYTTH
What are the official names of this protein?
HTH-type transcriptional regulator SarZ, Staphylococcal accessory regulator Z.
What is the protein family that this protein belongs to?
Belongs to the SarZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_PLAYO
Sequence: MAVGKNKRTSKGKKGGKKKVTDVFTKKEWYDLNAPKMFMVRKFGKTLVTKTIGKKLATDGLKGRIYEVNLADLNNDEDQAHKKIKLICDHIINRDCYTDFCGLSITRDKLCSLIRKGYTLIEGCTDVKTIDNYHLRMFCIAFTKKRPNQTKTTCYAQTSQIKKIRKKMVDIMHAEASKVLLKDLVKKIIPESIGKEVEKQCKKIFPLQNVLIRKVKILKRPKLDISKLMELHSDPKEDSGKNVKSLPESKEATNILTAELKH
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_CLOTE
Sequence: MSFDFLKYIKKVHFIGIGGISMSGMAEILLKKGYKVSGSDSTKSPIIDKLINLGAEIYIGHKAENIKNVDLIVYTAAVSEDNPELTKALTNNIKIMNRAEFLGYLMDGHKYNIAVSGTHGKTTTTSMMSHITVNANLDPTILVGGELNIINGNVRTGKSEYFLTEACEYKESFLKFFPYIGVILNIDADHLDYYKDINHIKNAFSKFANLIPKDGYLIACAEDENINDIIKNIDCTIITYGLNKGDIQAKNITFDNKGCASFDVIKNSSVLFSVKLNVPGSYNVLNALASICVSFALNIDKESIIKGLESFHGTHRRFELKGVRNDVTVIEDYAHHPTEIKATLSAAKNYPSNRILCVFQPHTYTRTYSLFEDFTESFYNTDTLILADIYPAREKDTGIVSSDMLGNKLRKKNINCINLHSFEDISDYLKKETKPGDLVLIMGAGDIYKAGDLFLK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFF_ECOL6
Sequence: MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1821_STRPB
Sequence: MLTFLIPTAKEMVIPKESYPHLLPQPSQAILKAMAAMTTEDLAKSYRIKEEAAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQVYITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSSEFDDVFSKDCKQLWISPKFMAEKEGRFKTHSTISKKARGAFLTACMENNCQTVDSLKSLVFAGFYYHPDLSTDHEFVYIKKEA
What are the official names of this protein?
UPF0246 protein MGAS2096_Spy1821.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: SMG_VIBVU
Sequence: MMMDILMYLFETYIHSDADLQVDQDELEDELLRAGFHQQDIYKALLWLEELAALQQSDAHSAISRCSAVSSTRVYSPKEMQRLDIECRGFLLFLEQINVLTTETREMVIDRVMGLETNEFELEDLKWIILMVLFNVPGNENAYTLMEELLYTKEQGILH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: PURA_CRYNJ
Sequence: MAPSPEGVTVVLGAQWGDEGKGKLVDILAAEADICARCAGGNNAGHTIVVRNDKGEKTSYAFNLLPSGLINPECTAFIGSGVVVHVPSLFNELDTLERKGLKVAGRLFVSDRAHLVMGFHQIVDGLKEVELGGSSIGTTRKGIGPAYSSKASRSGLRVHHLFDPTFPAKFRKLVEGRFKRYGHFEFDTEGEIEMYLAFAERLRPFIVDGPTFMHNAVNSGKRVLVEGANALMLDLDYGTYPFVTSSSTSIGGVVSGLGISPFAIKRVVGVIKAYTTRVGGGPFPTEDLATVGETLQEVGAEYGTVTGRRRRCGWLDLVVMKYSTMINGYTSLNLTKLDVLDGFDEIKVATGYKIDGVEVEGFPADLDRLAKVEVQYATLPGWKTDISNCKTYEEFPENAKAYIKFIEDYLGVKVQYVGVGPGRDQNVIIF
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTD_KLEP7
Sequence: MTDLPASVRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMIIVSYVLTVAVMLPASGWLADRVGVRNIFFTAIVLFTAGSLFCAQASTLDQLVMARVLQGVGGAMMVPVGRLTVMKIVPRDQYMAAMTFVTLPGQVGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAIATLCLMPNYTMQTRRFDLSGFLLLAAGMATLTLALDGQKGLGISPAWLAGLVAVGLCALLLYLWHARGNARALFSLNLFRNRTFSLGLGGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVASTLGLAAVSLLFMFSALAGWYYVLPLVLFLQGMINASRFSSMNTLTLKDLPDDLASSGNSLLSMVMQLSMSIGVTIAGLLLGLYGQQHMSLDAASTHQVFLYTYLSMAAIIALPALIFSRVPDDVGSNTVLRRRNRSGS
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIC_XYLFT
Sequence: MNITTALPLPTHLLSEKVTAPLLGARKIYVTGSRQDIRVPMREIALTPSSARYGGNENLSLVLYDTSGIYTDPQATIDLACGLPRLRTAWIDERADTVEAKLHFKVPESVSVTAPPFPTPPQPLRARDNVAVTQLEYARRGLVTPEMEFVAIREQQRREQTVENLRGQRHAGDAWGALVGTPITPEFVRDEIARGRAILPNNINHPESEPMIIGRNFLTKINANIGTSALSSSIAEEVEKLVWAIRWGADTIMDLSTGRDIHATREWILRNSPVPVGTVPIYQALEKVDGHVDALSWDVFRDTLIEQAEQGVDYVTVHAGVLRDFIPLTASRLTGIVSRGGSIMARWCQAHRSENFLYTHFEELCEIMRAYDVAFSLGDGLRPGCIADANDAAQFAELEILGKLTHIAWNHQVQVMVEGPGHVPMQLIKANMDKQLAACGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNLQDVHDGIIAYKIAAHAADLAKGHPAAQARDDALSKARFEFRWQDQFHLSLDPEKALALHDESLPKEAHKRAAFCSMCGPQFCSMKISQEVRDASSSELSDANTDINTSDGI
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: Y3745_BRUSU
Sequence: MKEVSLRGISKTFGQLTVLDRIDLEIHSGEFLVLVGPSGCGKSTLLRMVAGLEPISGGDLVIGGERANELPPQKRNIAMVFQSYALFPHMTARENIGFGPRIRGEKAAETAAKVDHAASILNLHSYLDRYPRQLSGGQRQRVAMGRAIVREPSVFLFDEPLSNLDAQLRVQMRTEIKALHQRLKSTVIYVTHDQIEAMTMADRIVVMNQGKIQQIGAPLDLYDRPANKFVAGFIGSPSMSFIPGTVADGFFCTGEGKKIAVSAAAKGARAAEAGIRPENFVIAREGAGLTLVVEVIEPTGPETHIYGRIAGEPVRAVFRERIQLAPGEQVPVTAGSEHIHLFDKESGLPL
What is the function of this protein?
Probably part of an ABC transporter complex.  Probably responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Putative ATP-binding protein BRA0745/BS1330_II0738.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL331_STAEQ
Sequence: MRVNVTLACTECGDRNYISTKNKRNNPERVEMKKYCSRDNKHTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RGI2_YEAS7
Sequence: MTKKDKKAKGPKMSTITTKSGESLKVFEDLHDFETYLKGETEDQEFDHVHCQLKYYPPFVLHDAHDDPEKIKETANSHSKKFVRHLHQHVEKHLLKDIKTAINKPELKFHDKKKQESFDRIVWNYGEETELNAKKFKVSVEVVCKHDGAMVDVDYKTEPLQPLI
What is the function of this protein?
Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.
What are the official names of this protein?
Respiratory growth induced protein 2.
What is the protein family that this protein belongs to?
Belongs to the RGI1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y701_ERWT9
Sequence: MLMVISPAKTLDFASPLATERFTQPALLAESQKLINVARKLSPADIASLMHISDKLAVLNAERFNDWQPAFTPDNARQAILAFKGDVYTGLQAETFGEEDFTFAQQHLRMLSGLYGLLRPLDLMQAYRLEMGIKLANPAGKDLYSFWGDKLTTALNEALAQQGDNLLINLASDEYFRSVKPKRLEADIIKPVFLDEKNGKFKVISFYAKKARGLMCRYIIQNRLTKVEQLKKFDLDGYAFDGDTSSNNELVFKRREMA
What are the official names of this protein?
UPF0246 protein ETA_07010.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: SCXN4_MESEU
Sequence: MNYLILISFALLVITGVESARDAYIAKPHNCVYECFDAFSSYCNGVCTKNGAKSGYCQILGTYGNGCWCIVLPDNVPIRIPGKCHR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This toxin inhibits inactivation of drosophila DmNav1 (EC(50)=130 nM) (PubMed:21969612, Ref. 2).
What are the official names of this protein?
Sodium channel neurotoxin MeuNaTxalpha-4.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.