Protein: GCYB_PLAF7
Sequence: MKTQTLSLMNINGKRKFLGTNNKIYRKVIINPTSEDDIQKFCRNYFRIYNFSLYNFIRRLISFDAILVYSLFLTVYIFSEINHGETKKYLFIDTAISLFFNIILLIVIESLFELKKLKDVKNANSQYYLRIVPKMSYFEKVMTKDIKVGNIIRIFQGDEFPADVVILYVKNNANAIVDSFKIDGLFRKSIKYAVDKYKIDKDYLKMLSEINGVIRCELPNKNIFCFQGNFKLDKHPRSLLLNYENFALQSSVLKGAEYIDAVVVYTGADTKKNLNIPQKIEENKTFCIKMNNIVYYLIFMYFVFVVLSIVIKTIFFHKKNSFQNSRDSFLSMLEDFVGLYILVLPIMMYSEKSLIYIIQSLRIENDLRMRNTDSEKPKVFNKNKNDSLGNVDLLATSRNGVLVKRKELLVSCVINNVMYGKKDIICSRTNFKLPTLNILDSERKNVSNLLNLDERIFKDPENIFFPTRDFYSFLKLFENKISSIYNPYSSSLSNLLKEKYKNYVNEEILNKNVKLTSFVKSQLTIGYNQICEDDELSYNCYEIKEDSQKENIQSVKIEDFILGLCGCNRIIIYNEKSLDISMNEYKSDNFMETYSKFETENEEYHENDHDEYHNMEHSDDENINSIEYEDICLYNIIRNTGFSIYCYKNTLFLYNLMKECKVYFLTCYHDFLRSNKFSMCILKCGYSINNEKEGGILYVRGYDFNILPYISKEKNNIKKIKNVIKIYTLNYLKVIILCKKQISNEDIAKYIILKSISKKLSFKFYDLIKLFFLYDLEVIGIIGLKNQLREGVKETFNDVINFDIKSWIFANECSKDTYLTALQCNLIVSSSNLFLINYYNLKNTHEEGANILFHNFISSLYKLKSNSYAVVINDESIKNIMTNVESMKIFLCIAMRATVVLFCKLQNETKGKIIRTLYALTSPKLTVLGIGTTLNDAYLLKYSSISVFLSLNEHVNILYNISDYVLQEFKFISELLILGRLNRFSLCKVFLWIIYLKITVVSFYFFHNFDNYFSGSSASSILYTQTTFALLHYFLIIAFSAYEIDLPYKFVRRLPYIYQLSRRKYFLNNNIILLTIIEAILISLTSYYILRLNVFHLITHREFTFHIFILNVFITTEKILLLSKTWHIYFFIMAVLIIGILLIYVNIFTLVDCIKNGKCEFSLFQMENIYFWTSLFPILYINFIFDKLMKYIKNRIYPDISDYLRKYFLRRICCHNNDKFLSQRKIKGINKFVNFEKNDILLKYIPTPKIYKIKDDPTYYNKSKRSKFLYDTFRKVIDINVKYRNQQLNLEYKTYEKGNKLKLRIIVILLFLIYIIIFSSQTIIDINTKSNIHYITMFYIIYFVLACVLLIYIRIRNKATSTFFFFLSRFLLICGFCIELYDNISNDILNVLITYSFTVSYIFFMSFKILEALLVCISILLLTFGVYYEKNKNMIDICTHFCSNPYLSINNLDHMNISCLCKKQIVIFLISLLSFTLICLSMKYYEIFYLKKKFLFRYKQKVNLAKQIEILHTMLPNFLVEYLLISDPKNDGIMVGKNISGEDRGIISVIFCDIDDFQNMVSTLQPHVLVETLDNLYLYFDKCIKYFNCIKIETVFESYLAASGLSEKKNNALDKIMYDTKCAIKLAIAQLSAKYYISYKVLDTREHFSDNSTSYDKYINKNISLKIGIHTGKAISGVIGSVKPQYALFGDTVNTASRMKSTSLPDHIHVSYDTYKYLKEDNTFIWKERKVFIKGKGKMKTYLLVDILDDVKRKGESLNYYSSSNLLLSQLGSEAVSIYEEREDIKEGSMDIIKESSRDIIKEDSRDIIKEISTNISKSSSRNISKSSSRSISDIKEGQIIDKEDLIFKINRMKNKIDSRYSKRIDKESRDKISDKTNHVLDEVVKHSDIHLLNYEINNKRCKKMKGDTNNENKLIGDIFNMYDKKIKYIYKKNYKSKSMENISFIKHYRNTKYKKSDYLLLDNKGESKKFKRNTSYVLESPLHLIGDIVDNNIKRKKKKKEIKTIVSDDMFTSPVNIKEYNYNEQERKKEIVGNLSYDKTKKIFPFIKFTKEGRIKKKKIEKKEKKEKKENNNNFLYNDDYSSYSSPKYGDNENNFVIKYIRERKDFQKKFDHPNFNFSKFLHNYNPMKNKNKNKKNNKNVRRNEYPNYTSSSKDGVSYNFLSDSLFSSDNEYSSDNEYSSDSEKYYKKRFKKNKKIIKFDDLFTKIYIKKKRLLQMNNYDVKGKGKKLKNKGMERNKTKYKNVNEITKMKYFVNNENRDHEVNKEDISKSMQKYFLHISKHKKEQIEDKKKTHKYFHKNVECVYPYAGNNINHNFSRNEKRKYSINLYDHLDEQEKIKGKKKYFNKDKELIGSINKQTERKPKKKNKKNIENKKDKKKIRMITNKTKEKHSNSIISVEEQNMNHNNSLKKKEVNFTGKNEEYLNRANTNCSLGIKEMEEDVYEFHSNNIYYNNQTSYSDDINNTTKLKGMGNNTNDISKNKGKNKLGKKISFFSMNNKYHESEIMNEEDNKNMLNLTQSQIINKDKYNYFTHCPSLKKKKSVFTKINNLFKNYFKSIDVHEKFGFSKKFKFHSKDSDDIKGNNNKISKNRYNNNNNNNNSNYSNIDSGKYSHNNKKNHHHNNNKYHHHNNNKYHHHNNNKYHHQNNNYEKHHHSNNSRVMLSKGEKTEKNENVDYAYQFDNYDKKLLKKLTSNLQLNKKNVKNFNMFYYKFNDEELEEEYTRNYYREIINIDLTKKLIIIFIFTEIFLSLCNIIELSFYEKKLRYNDSIVIIWLIRSIYLFIITYIWIILKTKLKEYKNNSSKMMWTIFILNIFLCSWGIILIDLSCIHYSMLLGNKNERALFFMKDASELIICIQLIFIKNMLFKHKFFFFVFFYIFLIYSFSKLFSIHTCQTHICCSIILFISINILYFWYSEYLDRIQFLVKRKRNRMEKISQDFLTKILPRQVLEEYQNDNLQLTYKHEKIAFLFADIVGFTKWSKTVSPKEVLKLLQKLISKIDKDTIKLGLYKLFTIGDAYVATSQPNSSITDESEALEGILNILKLAKLILHNINTIKIQFNKHDFNMRIGLHYGSCVGGIIGSVRIRYDMWGLDVLIANKIESNGIPGEIICSEQFRHFFIQNEPQAKLNFWYYKSISINDQDIKLYVIEDKNYEEDYDPKVIDYTTLLKLRQKKGLRS
What is the function of this protein?
Catalyzes the synthesis of the second messenger cGMP from GTP (PubMed:10747978, PubMed:11703675, PubMed:18452584).  Regulates cGMP production in gametocytes; however, is dispensable for the initiation of gametogenesis (PubMed:18452584).  Does not have adenylate cyclase activity (PubMed:10747978).
What are the official names of this protein?
Guanylate cyclase beta, PfGCbeta, Guanylyl cyclase beta.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.