PharMolix/UniProtQA huggingface dataset:
Protein: PLIN2_HUMAN
Sequence: MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTESQNAQDQGAEMDKSSQETQRSEHKTH
What is the function of this protein?
Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.
What are the official names of this protein?
Perilipin-2, Adipophilin, Adipose differentiation-related protein, ADRP.
What is the protein family that this protein belongs to?
Belongs to the perilipin family.
Protein: YQGF_BACAH
Sequence: MRILGLDVGTKTVGVAISDEMGWTAQGLETIKINEERGQFGFDRISELVKQYDVDKIVVGLPKNMNGTIGPRGEACQQFAENLRELLQLDVVMWDERLSTMAAERLLISADVSRKKRKQVIDKMAAVVILQGFLDSK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIM14_BOVIN
Sequence: MAEGGFDPCECVCSHEHAMRRLINLLRQSQSYCTDTECLQELPGPSSDNGISITMILMAWMVIAVILFLLRPPNLRGSNLTGKPASPHNGQDPPAPPVD
What are the official names of this protein?
Small integral membrane protein 14.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RL7_KLEP7
Sequence: MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGISKDDAEALKKSLEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: US10_GAHVM
Sequence: MAMWSLRRKSSRSVQLRVDSPKEQSYDILSAGGEHVALLPKSVRSLARTILTAATISQAAMKAGKPPSSRLWGEIFDRMTVTLNEYDISASPFHPTDPTRKIVGRALRCIERAPLTHEEMDTRFTIMMYWCCLGHAGYCTVSRLYEKNVRLMDIVGSATGCGISPLPEIESYWKPLCRAVATKGNAAIGDDAELAHYLTNLRESPTGDGESYL
What are the official names of this protein?
Virion protein US10 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US10 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus matrix.
Protein: RM16_ACAPO
Sequence: KNVNETLLLRALKSSSLRLPVPTKIIKKYDKRTDCIKGS
What are the official names of this protein?
60S ribosomal protein L16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS6_THENN
Sequence: MAYVKERIYESMFIIAPNVPEEEREKLVERVKGIIEERVKGKIDKVERMGMRKFAYEIKKFSEGDYTVIYFRCDGQHLQELENFYRITPEIIRWQTFRRFDLEKKERKAQSEKKEAEVSEGEGGTEA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PRSA2_BACCR
Sequence: MRGKHIFIITALISILMLSACGQKNGSATVATATDSTITKDNFEKQLKDRYGKDMLYEMMAQDVITKKYKVPDEEVNKEVEKVKKQYGDQFKKVLENYGLKDEEDFKNQIKFKLAMNEAIKKSITEKDVKDHYKPEIKASHILVSDENEAKEIKSKLDAGASFEELAKQESQDLLSKDKGGDLGYFNSGTMAPEFETAAYKLNVGQISNPVKSSNGYHVIKLTDKKALKPYDEVKDSIRKNLEEERTADPVFSKKLLQEELKKANIKINDSDLKDTFTLVSPQGN
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 2.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: KU70_NEUCR
Sequence: MSWRKDQDERLDGDEGDEELDENDYKTQKDAVLFAIDVSKSMLKPPQNTGDKKADKDSALTAALTCAYQIMQQRIISQPKDMMGVLLFGTEKSKFRDDSGNGTGYPHCYLLSDLDIPGAEDVKKLKALIEDGDDEDEIMVPSKEPVIMSNMLFCANQVFTTNAANFGSRRLFIVTDNDDPHAGDKQAKSSAAVRAKDLYDLGVVIELFPISREDKKFDLSKFYDDIIYRNPAAEAGQSESPKTSKSGDGLTLLNSLISNINSKQTPKRSYFSNLPFELAPGLTISIKGYMPLNRQTPTRSCYVYEGEEQAQVVQSETAQVDFAARTVEKSELRKGYKFGGEHICFKPEELAELKQMGKKTLRIIGFKKRSKIPSWASVKKSIFIFPSEEQYVGSTRVFSALWQKLLKDDKVGIAWFVARENAHPVMVAIFPSGNPDDEEANTPYLPAGLWLYPLPFADDVRSVDHVTAPPRPADELTDQMRQVIQNLQLPKAMYDPRKYPNPSLQWHYKILQAKALDEETPDAMDDVTLPKYRQIDKRVGGYLAEWKEMLAKKANDLQNTRAFKREFEEDDERPAKRAKPSKKAASGGGGPANSNADLKKAFEQGTLGKMTVAELKDIMASKGISTAGRKAELVERLEQWVEENL
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair.  DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA.  Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection.  Required also for telomere recombination to repair telomeric ends in the absence of telomerase.  ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase.  Involved in telomere maintenance.  Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement.  Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere.  Required for mating-type switching (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase II subunit 1, ATP-dependent DNA helicase II subunit Ku70, Protein mus-51.
What is the protein family that this protein belongs to?
Belongs to the ku70 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: MT2H_BOVIN
Sequence: MDPNCSCATGGSCTCANSCTCKACKCASCKKSCCSCCPVGCAKCAQGCICKGASDKCSCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.  This isoform may play a role in regulating the transport, accumulation, and compartmentation of zinc in the hippocampus.
What are the official names of this protein?
Metallothionein-II, hippocampal, MT-2.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: MFM4_PHOSM
Sequence: MPSILTDFNVRPYEDVPAQIIELSVPDAAAPKHCPIQLLYWPVEGKSNFIRGYENLKDGLSRLLADVPVLVGRLERGSKGDPRYLAVTISSDASVELEYEDISADDTIASYDDLVRNGFPTTGFKDIVSPKMSLGPMVEGSPMMCAKLNLIKGGAILAYGFSHVLADGWANSELGRLWALHAAHVSQGIGFERQKAATPDDEIRRQLSTLPDFDADAPLDAFLQITPSEEATNFLHKDVLAAEKAKKKAREKMMATLLAAGEVPELPRFTFWRFTPEKLKELKQAATSSDASKWISTMDALAGLFWSRIARIQGQSSNGHQQSRCIFALDIRRRLQQPVPLAYVGNVFSPVDAICPLDELESDSLGLKAAAQSMRQANKGWTQPRWEAWLNKIMSLPLDQTLDTSQEFRLQKHNMYFNDYSAFQLNTASWGAPFGQPARTRCLRSGLAGGAAGVWVCPKFPDGSLEVWLTSTAAIQKSLFEDATFNRYAEFVCQYT
What is the function of this protein?
Acyltransferase; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS) (PubMed:27056201).  SQS1 is composed of a 2,8-dioxobicyclic[3. 2. 1]octane-3,4,5-tricarboxyclic acid core that is connected to two lipophilic polyketide arms (PubMed:27056201).  These initial steps feature the priming of an unusual benzoic acid starter unit onto the highly reducing polyketide synthase pks2, followed by oxaloacetate extension and product release to generate a tricarboxylic acid containing product (By similarity).  The phenylalanine ammonia lyase (PAL) M7 and the acyl-CoA ligase M9 are involved in transforming phenylalanine into benzoyl-CoA (By similarity).  The citrate synthase-like protein R3 is involved in connecting the C-alpha-carbons of the hexaketide chain and oxaloacetate to afford the tricarboxylic acid unit (By similarity).  The potential hydrolytic enzymes, M8 and M10, are in close proximity to pks2 and may participate in product release (By similarity).  On the other side, the tetraketide arm is synthesized by a the squalestatin tetraketide synthase pks1 and enzymatically esterified to the core in the last biosynthetic step, by the acetyltransferase M4 (PubMed:11251290, PubMed:15489970, PubMed:28106181).  The biosynthesis of the tetraketide must involve 3 rounds of chain extension (PubMed:11251290, PubMed:15489970, PubMed:28106181).  After the first and second rounds methyl-transfer occurs, and in all rounds of extension the ketoreductase and dehydratase are active (PubMed:11251290, PubMed:15489970, PubMed:28106181).  The enoyl reductase and C-MeT of pks1 are not active in the final round of extension (PubMed:11251290, PubMed:15489970, PubMed:28106181).  The acetyltransferase M4 appears to have a broad substrate selectivity for its acyl CoA substrate, allowing the in vitro synthesis of novel squalestatins (Probable).  The biosynthesis of SQS1 requires several oxidative steps likely performed by oxidoreductases M1, R1 and R2 (Probable).  Finally, in support of the identification of the cluster as being responsible for SQS1 production, the cluster contains a gene encoding a putative squalene synthase (SS) R6, suggesting a likely mechanism for self-resistance (Probable).
What are the official names of this protein?
Acyltransferase M4, AT M4, Squalestatin S1 biosynthesis cluster protein M4.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: CHEB_MARMM
Sequence: MTELAPKASPAHSIARVLVIDDSAVARGLMTRWVEEDSDLTLIGSAVDGEQGLRKAEELKPDLIVLDVEMPKMDGLAALPLLLKAVPGCKIVMASTLTRRGGEVTIRALSMGAADYASKPQAGRLAGAEEFRRDLLLKLKALAPRPIPPVPTQRDMAPSPAPATPAAPGAPVARSITPPPPPSSSAPAKKAFAPVAQPPQGRGTPRNTARPEIIAIGSSTGGPQALRDVIAAFPADVRSPIVIAQHMPALFTKILAEHLTKAGKLVCKEAEDNERLKPGCVYIAPGDFHMTIRKDAAGFYAVLDQTPPINFCRPAVDPLFQSVAEVTRGAALGIVLTGMGHDGREGARMLRSVGGTILAQDEATSVVWGMPGAVAEAGLADEILSLADMGPGIVRRAKGGN
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIEL1_ARATH
Sequence: MEASPNDRLHFGKMGFGCKHYKRRCQIRAPCCNEVFDCRHCHNESTSTLRNIYDRHDLVRQDVKQVICSVCDTEQPAAQVCSNCGVNMGEYFCSICIFYDDDTEKQQFHCDDCGICRVGGRENFFHCKKCGSCYAVGLRNNHRCVENSMRHHCPICYEYLFDSLKDTNVMKCGHTMHVECYNEMIKRDKFCCPICSRSVIDMSKTWQRLDEEIEATAMPSDYRDKKVWILCNDCNDTTEVHFHIIGQKCGHCRSYNTRAIAPPVLPQ
What is the function of this protein?
E3 ubiquitin-protein ligase that acts as a regulator of cell death and defense.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Attenuates the activation of defense and related cell death responses in the absence of pathogens by mediating ubiquitination and subsequent proteasomal degradation of MYB30.
What are the official names of this protein?
E3 ubiquitin-protein ligase MIEL1, MYB30-interacting E3 ligase 1, Pirh2-like protein 1, AtPILP1, RING-type E3 ubiquitin transferase MIEL1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECA_XANCB
Sequence: MDENKKRALSAALSQIEKQFGKGSVMRMGDRVIEAVEVIPTGSLMLDIALGIGGLPKGRVVEIYGPESSGKTTLTLQAIAECQKLGGTAAFIDAEHALDPIYAAKLGVNVDDLLLSQPDTGEQALEIADMLVRSSSVDIVVIDSVAALTPKAEIEGEMGDQLPGLQARLMSQALRKLTGNIKRSNTLVVFINQLRMKIGVMMPGQSPEVTTGGNALKFYASVRLDIRRIGAIKKGDEIIGNQTKIKVVKNKLAPPFKQVITEILYGEGISREGELIDMGVEAKLVDKAGAWYSYGDERIGQGKDNARGYLRDNPQVAIKLEAELREKFQPAEAPREAGETESE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_FRAT1
Sequence: MSRIGKKPVVIPSGVTINVAAGNKVEVKGAKATLSKTFSTDVTFSVADNVATITPNNNSKNAVAQSGTARAILSNMVEGVSKGFERKLKIIGVGYRAKAQGNELNLTLGFSHPVVYKLPQGITAETPAPTEIILKGADKELLGKVASEIREYRKPEPYKGKGVRYEDEYVAKKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: OTC_CLOAB
Sequence: MGYLKNRNFLSLMDFTPQDINYMLDLAKKLKEDKRNGLEEQYLKKKNIALIFEKDSTRTRCSFEVAAHDQGAHAVYIGSTGSQISKKESIKDTARVLGRMFDAIEYRGYGQEVVEILAEHSNVPVWNGLTDEEHPTQVIANFMTLKEKFNKPLNEIKFVYCGDARNNVSNALMIGAAKMGMDFRIAAPKSLFPSSELVKKCMDIAELTGGKITLSDEVDEAVFGADVLYTDVWVSMGEDREVWKERLKMLKPYQINMEMISKTKNPNVKFMHCLPAFHDFSTDAAKEIYDEFNEIPFEVTDEVFESDYSLAFDEAENRLHSIKAIMVATLGDI
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOA11_BOTFB
Sequence: MASATKTLITELTPLDHLMPRTYVIGMNYIWPISRRSNIEDIHKHLKRGLEQTIKEIPFLGGSVVPTGSPGKFCIETLPGDFEGNQLIFNDLRTGSGNSWPNSYKNVRKARFPSTLFTDDCLSPVKGYMTRERLPVIAAQANFIDGGLILHLSVLHTACDVLAWNNILSILSKNVKASWPTEAEVSLNDDLQDYKVLPSFLDRSPLMRGNLNVERMDVREYKLQLANSKLEDPRNHLINPPPKSITEMENALFCISNSKLGELRDSISAEGSATSWLTVNDALAALMWCCVNRARISNGSQKLLRGNLSVAYDGRTVLDPPLPKRFMGNSALGFPITLDIHPKSVFEAALAISESRNDFNDKHIRDIIGFLDGLGDITQERVSYAKTLNPILVISNLKDMGFYEQDWGGSLGFPDALRMANPFLDYIPRVVPMPAQRNGNVYLIVWIEKSAAKRLREDETWNKWITPVFE
What is the function of this protein?
Acyltransferase; part of the gene cluster B that mediates the biosynthesis of botcinic acid and its botcinin derivatives, acetate-derived polyketides that contribute to virulence when combined with the sesquiterpene botrydial (PubMed:21722295).  Botcinic acid and its derivatives have been shown to induce chlorosis and necrosis during host plant infection, but also have antifungal activities (PubMed:21722295).  Two polyketide synthases, BOA6 and BOA9, are involved in the biosynthesis of botcinins.  BOA6 mediates the formation of the per-methylated tetraketide core by condensation of four units of malonyl-CoA with one unit of acetyl-CoA, which would be methylated in activated methylene groups to yield a bicyclic acid intermediate that could then either be converted to botrylactone derivatives or lose the starter acetate unit through a retro-Claisen type C-C bond cleavage to yield botcinin derivatives (PubMed:23203902).  The second polyketide synthase, BOA9, is probably required for the biosynthesis of the tetraketide side chain of botcinins (Probable).  The methyltransferase (MT) domain within BOA6 is probably responsible for the incorporation of four methyl groups (Probable).  The trans-enoyl reductase BOA5 might take over the enoyl reductase function of BOA6 that misses an ER domain (Probable).  The monooxygenases BOA2, BOA3 and BOA4 might be involved in further hydroxylations at C4, C5 and C8, whereas BOA7, close to BOA9, could potentially be involved in the hydroxylation at C4 in the side chain of botcinins (Probable).
What are the official names of this protein?
Acyltransferase BOA11, Botcinic acid biosynthesis cluster B protein 11.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: CSD_STAAN
Sequence: MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPMQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: PIP22_MAIZE
Sequence: MGKDDVVQSGAGGGEFAAKDYTDPPPAPLVDAAELGSWSLYRAVIAEFIATLLFLYVTVATVIGYKHQTDASASGAGADAACGGVGVLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSLVRALLYMVAQCLGAVCGVGLVKAFQSAYFDRYGGGANSLASGYSRGAGLGAEIVGTFVLVYTVFSATDPKRNARDSHVPVLAPLPIGFAVFMVHLATIPVTGTGINPARSLGAAVVYNKDKPWDDHWIFWVGPLLGAAIAAFYHQYILRAGAIKALGSFRSNA
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin PIP2-2, Plasma membrane intrinsic protein 2-2, ZmPIP2-2, ZmPIP2;2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RH47_ARATH
Sequence: MAASTSTRFLVLLKDFSAFRKISWTCAATNFHRQSRFLCHVAKEDGSLTLASLDLGNKPRKFGKGKAMKLEGSFVTEMGQGKVRAVKNDKMKVVKEKKPAEIVSPLFSAKSFEELGLPDSLLDSLEREGFSVPTDVQSAAVPAIIKGHDAVIQSYTGSGKTLAYLLPILSEIGPLAEKSRSSHSENDKRTEIQAMIVAPSRELGMQIVREVEKLLGPVHRRMVQQLVGGANRMRQEEALKKNKPAIVVGTPGRIAEISKGGKLHTHGCRFLVLDEVDELLSFNFREDIHRILEHVGKRSGAGPKGEVDERANRQTILVSATVPFSVIRAAKSWSHEPVLVQANKVTPLDTVQPSAPVMSLTPTTSEADGQIQTTIQSLPPALKHYYCISKHQHKVDTLRRCVHALDAQSVIAFMNHSRQLKDVVYKLEARGMNSAEMHGDLGKLGRSTVLKKFKNGEIKVLVTNELSARGLDVAECDLVVNLELPTDAVHYAHRAGRTGRLGRKGTVVTVCEESQVFIVKKMEKQLGLPFLYCEFVDGELVVTEEDKAIIR
What is the function of this protein?
Essential protein required during embryogenesis.  Required for mitochondrial metabolism.  Necessary for normal plasmodesmata (PD) development and aperture regulation.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 47, mitochondrial, Protein EMBRYO DEFECTIVE 1586, Protein INCREASED SIZE EXCLUSION LIMIT 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DUSP_FOWPN
Sequence: MDEKQLYKHIITKSTNTCVKFTPRDITKITDYVYLGNYRNVIELPNKTFFKYIVNVSMLKYKLKRTDITVLHFPLEDNDTVSISKHIDAVTYVLKKCESLKIPVLVHCMAGINRSSAMIMGYLMEIRDKNIPFVIYFLYIYHELKYIRGAFIENKSFLNQIIDKYI
What is the function of this protein?
Serine/Tyrosine phosphatase which down-regulates cellular antiviral response by dephosphorylating activated STAT1 and blocking interferon (IFN)-stimulated innate immune responses.
What are the official names of this protein?
Probable dual specificity protein phosphatase H1 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Approximately 200 molecules of H1 are packaged within the virion and are essential for the viability of the virus.
Protein: LIPA_RHOBA
Sequence: MIFCLSSGQTPMAFRLPVVAEPEMPAGTDVSSTGRLPRWLKRPIPKSNSNHLTDSLMEEYGLETVCDNAKCPNRMECYSQQTATFMVLGNVCTRPCGFCAVSRGRPPAAPAVDEPDRIAKAAERLGLKHVVITSVTRDDLPDGGADHFHNCVIAVRERTGATTEVLTPDFVHCKEALARVIEAKPTVFNHNMETVPRLYRRVRGPKSDYAWTLEMMRQVKRYDAEVKTKSGLMLGLGEERGELLDALSDLREHDVDFLTLGQYLQPGEKYLPVVRYVPPEEFDELADIAKSMGFKKVASGPFVRSSYHARDMAETE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_CUPNH
Sequence: MTQIHPTALVDPKAELASDVTVGPFSIVGPNVRIGSGTRVGSHTTVEGYTTIGEGNTIGPYASVGGVPQDMKYRNEPTRLEIGDRNTIREFTTIHTGTVQDRGLTSLGNDNWIMAYVHIAHDCTVGNHTVFSSNAQIAGHVEVGDWAILGGMSGVHQFVRIGAHAMLGGASALVQDVPPFVIAASDKSGNKATPHGVNVEGLRRRGFDAGQIAALRQAYKLLYKSDLSFDEARNEITALLGQSDAGTAAPLRAFVDFLAATQRGIVR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNGA1_RAT
Sequence: MKTNIINTWHSFVNIPNVVVPAIEKEIRRMENGACSSFSDNDNGSLSEESENEDSLFRSNSYRRRGPSQREHYLPGTMALFNVNNSSNKDQDPKEKKKKKKEKKSKADDKKESKKDPEKKKKKEKEKEKKKEEKPKEKKEEEKKEVVVIDPSGNMYYNWLFCITLPVMYNWTMIIARACFDELQSDYLEYWLIFDYVSDVVYLADMFVRTRTGYLEQGLLVKDELKLIEKYKANLQFKLDVLSVIPTDLLYFKFGWNYPEIRLNRLLRISRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVYYSISKAIGFGNDTWVYPDVNDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVLDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQSRVDAIKQYMNFRNVSKDMEKRVIKWFDYLWTNKKTVDEREVLRYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGITQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGRQILMKDGLLDINIANLGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIETEFSALEEPGGESEPTESLQG
What is the function of this protein?
Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway.  When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.
What are the official names of this protein?
cGMP-gated cation channel alpha-1, Cyclic nucleotide-gated cation channel 1, Cyclic nucleotide-gated channel alpha-1, CNG channel alpha-1, CNG-1, CNG1, Cyclic nucleotide-gated channel, photoreceptor, Rod photoreceptor cGMP-gated channel subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.