PharMolix/UniProtQA huggingface dataset:
Protein: RLMKL_LEGPH
Sequence: MNYSLFISCSKGLEYLLEDELKGLGLHVTQVSPQGVYGEASLPVIYNLCLWSRLANRIQLILFSGHATKEQAVHQLCTDFHWQTVFTHDKTIAIEFHGASEQIRNTMFGAQIVKDGIVDHFRRLNGSRPSVDKEKPQILIHAHLKNDILTVSFDLVGYSLHQRGYRKKAGKAPLKENVAAAMLLRAKWPELAAQGYSLHDPFCGSGTLVIEAAMMAAHIAPGLLRQDQSLQYWARHQSSLWEKLRTQALQQVKPLAVKLIGTDADSKIITLARSNAERAGVLPLVEFNTLSLNACRPGTKRGLVVCNPPYGERLGEVTQLVPLYQELGTTLHTCYQGWQAAILTSSPVLAKALGLRADKQYTLYNGPLECKLYCLTLSAANKLKNTPNAPLSDNAQMLFNRLEKNRNHLQKWARKNQITCYRIYDADLPEYAYAIDIYNDYAVLQEYAPPASIPVHKAEKRSLEMLQVVPRALGIHPEKLIVKQRKQQKGSEQYQKIGKTSQRLIVTEGKAKLIVNLYDYLDTGLFLDHRLMRLKFAQLEPGTRFLNCFCYTASASVHAALAGALTTNVDLSKTYLLWAEDNFRLNDINLSKHQFLQYDCKEWMKTTRDKFDVIFLDPPSFSNSKRMSDILDIQRDHVSLINMAMRLLNPDGVLYFSTNLRQFKLEPMLKEKYAVQDITPQTIDQDFKRNSKIHHCFKIVMPHFADN
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGAQ_ECO57
Sequence: MFSIKPGPRKLPIDNPSLLSWNITDGDLNSKLNTLEYLNCVTNIINACGVYPQDLKDREIISTFHAEKVINDLLKNDYKISLSPDTTYRELNKAAQRSITAPDRIGEGKIWVYQRDTMVERGDNSGVHQYGPAEHFTHIISDKPSPKDKYVAYAINIPDYELAADVYNINVTSPSGQQETFKILINPEHLRQTLERKSLTAVQKSQCEIITPKKPGEAILHAFNATYQQIRENMSEFARCHYGYIQIPPVTTFRADGPETPEEEKGYWFHAYQPEDLCTIHNPMGDLQDFIALVKDAKKFGIDIIPDYTFNFMGIGGSGKNDLDYPSADIRAKISKDIEGGIPGYWQGQVLIPFTIDPVTKERKQIHPEDIHLTAKDFEASKDNISKDEWENLHALKEKRLNGMPKTPPKSDQVIMLQNQYVREMRKYGVRGLRYDAAKHSKHEQIERSITPPLKNYNERLHNTNLFNPKYHEKAVMNYMEYLVTCQLDEEQMSSLLYERDDLSAIDFSLLMKTIKAFSFGGDLQTLASKPSSTISSIPSKRRILININHDFPNNGNLFNDFLFNHQQDEQLAMAYMAALPFSRPLVYWDGQVLKSTTEIKNYDGSTRVGGEAWLNKGCSTYQQLYNEFHALYIDKAGIWSAFEGVFATKNVLAFSRGDSVNINHSPHDGLVIINKGNEEVEGAWPNKLQPGKYKNMGSNSVNIIINNTRKIIPPGKAFMLRGGTLNINIPGRSALLLGKTGEPLNYLYL
What are the official names of this protein?
Putative uncharacterized protein YgaQ.
Protein: GGGPS_THEKO
Sequence: MLKLGKVETYIHEKLEREKLHFVLLDPDDVSPELAGELASMSEEVGVDAIMVGGSTGAEGEVLDSVVRAIKESSNLPVILFPGSHGGISKYADAIFFMSLLNSRNPFFITGAQALGAFQVKRYGIEPIPMAYLIIEPGETVGWVGDAKPIPRHKPKIAAAYALAGQYLGMRLVYLEAGSGAPQPVPPEMIGLVKRVIDVPLIVGGGIRTEEQARAAVKAGADIIVTGTAIEKAGSVEKAREKLEELNRGVKG
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_CERS4
Sequence: MLYLLTAFSDGGDIFNLFRYLTFRAGAAFFTALIFGFLFGRPLIDFLRRKQGKGQPIRDDGPTTHFAKAGTPTMGGLLILSALVVSTLLWARLDNPYVWIVLLVTVAFGLIGFADDYAKVKKQNTKGVPGRVRFLIGLLIAALAAIAAAWSHPPDLTLQLAMPFFKDALINLGWFFVPFAMVVIVGAANAVNLTDGLDGLAIMPVMIAGTTLGVIAYVVGNFNLTDYLGVHFVPGTGELLIFSSALVGGGLGFLWYNAPPAAVFMGDTGSLALGGALGAIAVCTKHEIVLAIVGGLFVTEALSVIIQVLYFKRTGRRVFLMAPIHHHFEKKGWAEPQIVIRFWIISLILALIGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CATIP_DANRE
Sequence: MEESELTQNETEELKASVSAVEFIHIAQRDLEQCLFADSLVTVSDSGRELGDFSVSVTKASYNEELCYLLHANSHGTIDDVPCGTSIVAYISRKLEILEENHHEYVKLEKKTVDRKIHIVRQDDQLVVDRVISEREGVKTQTLKFPLSSLDGFVSEASNFLLLRIMARQKIVPENMTFLSLDADSGLSKSVYKALGWQKQMVGEDLVDIFGIERTIYSANLSSATWHCFFMPDGHLASRVQLGSPAVMKLLHLPFLLDGVIKTFFFLVEKDKIPVMEKKPLIWEEDMELYSKFLDRKEELKADYSSYLRQHPELKALLADFLQFLLLRKPQDVFSFARDFFAPFASQSPPGKSQEF
What is the function of this protein?
Plays a role in primary ciliogenesis by modulating actin polymerization.
What are the official names of this protein?
Ciliogenesis-associated TTC17-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the CATIP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton.
Protein: DER_LIMF3
Sequence: MANPVVAIVGRPNVGKSTLFNRIAGERIAIVEDTPGVTRDRLYAHGEWLGKNFSMIDTGGIEMSDQPLLTQIRQQAEIAIEEADVIIMVVNVENGVTDADEQVAQILYRSNKPVVLAVNKVDNPERRLDVYDFYRLGLGEPYPVSSVHGVGLGDMLDAVIENFAEKDAEEEDDRIRFSFIGRPNVGKSSLVNAILGENRVIVSDMAGTTRDAINTQFTAKDGREFTMVDTAGIKKKGKLYENTERYALMRSMRAIDDSDVVLVVLNAEEGIRELDKHIAGYAHEAGRAVIIVVNKWDTIPDRDQRTMTDFTNLIRHEFQYLSYAPIVFVSAKTKQRLSRLPEMIEEAYDHQHRRIQSAVLNDVLMDALAANPTPSSNGRRLRVYYATQVAVAPPTFVIFVNDPDLMHFSYARYLENRIRAAFDFTGTPIRLIKRRRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: KAP2_HUMAN
Sequence: MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ
What is the function of this protein?
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.  Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
What are the official names of this protein?
cAMP-dependent protein kinase type II-alpha regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Colocalizes with PJA2 in the cytoplasm and the cell membrane.
Protein: YL796_MIMIV
Sequence: MSTPVSEKINNKMRFPFEGIYHTIFPTKFYTRVYCQHNEYQNSISAIAELRVPIGSTIAKYDSDHGMIRADKVIVEKITTVDNDIVSDDFYCGKFNKGAVLNYKDSFKTKHNYSSSGIHGSLYKEKAHYSYDGRLPSIGSSW
What are the official names of this protein?
Uncharacterized protein L796.
Protein: SOQ1_ARATH
Sequence: MALKLTSPPSVFSQSRRLSSSSLIPIRSKSTFTGFRSRTGVYLSKTTALQSSTKLSVAAESPAATIATDDWGKVSAVLFDMDGVLCNSEDLSRRAAVDVFTEMGVEVTVDDFVPFMGTGEAKFLGGVASVKEVKGFDPDAAKERFFEIYLDKYAKPESGIGFPGALELVTECKNKGLKVAVASSADRIKVDANLKAAGLSLTMFDAIVSADAFENLKPAPDIFLAAAKILGVPTSECVVIEDALAGVQAAQAANMRCIAVKTTLSEAILKDAGPSMIRDDIGNISINDILTGGSDSTRNSTAMLEENTVSDKTSANGFQGSRRDILRYGSLGIALSCVYFAATNWKAMQYASPKALWNALVGAKSPSFTQNQGEGRVQQFVDYIADLESKQTATTVPEFPSKLDWLNTAPLQFRRDLKGKVVILDFWTYCCINCMHVLPDLEFLEKKYKDMPFTVVGVHSAKFDNEKDLDAIRNAVLRYDISHPVVNDGDMYMWRELGINSWPTFAVVSPNGKVIAQIAGEGHRKDLDDVVAAALTYYGGKNVLDSTPLPTRLEKDNDPRLATSPLKFPGKLAIDTLNNRLFISDSNHNRIIVTDLEGNFIVQIGSSGEEGFQDGSFEDAAFNRPQGLAYNAKKNLLYVADTENHALREIDFVNERVQTLAGNGTKGSDYQGGRKGTKQLLNSPWDVCFEPVNEKVYIAMAGQHQIWEYSVLDGITRVFSGNGYERNLNGSTPQTTSFAQPSGISLGPDLKEAYIADSESSSIRALDLQTGGSRLLAGGDPYFSENLFKFGDNDGVGAEVLLQHPLGVLCANDGQIYLTDSYNHKIKKLDPVTKRVVTLAGTGKAGFKDGKVKGAQLSEPAGLAITENGRLFVADTNNSLIRYIDLNKGEDSEILTLELKGVQPPTPKAKSLKRLRKRASADTKIVKVDSVTSREGDLNLKISLPDGYHFSKEARSKFVVDVEPENAVAIDPTEGTLSPEGSTMLHFIQSSTSASVGKISCKVYYCKEDEVCLYQSVQFEVPFKVESELSASPTITFTVTPRAPDAGGLQLQGTR
What is the function of this protein?
Required to maintain light harvesting efficiency, especially during nonphotochemical quenching (NPQ) recovery, via the regulation of chlorophyll excited-state lifetime probably by preventing the formation of a slowly reversible form of antenna quenching.
What are the official names of this protein?
Protein SUPPRESSOR OF QUENCHING 1, chloroplastic.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein. Note=Mostly localized in thylakoid grana margins, and, to a lower extent, in grana and stroma lamellae.
Protein: THN2_WHEAT
Sequence: MGSKGLKGVMVCLLILGLVLEQVQVEGKSCCRTTLGRNCYNLCRSRGAQKLCSTVCRCKLTSGLSCPKGFPKLALESNSDEPDTIEYCNLGCRSSVCDYMVNAAADDEEMKLYVENCGDACVNFCNGDAGLTSLDA
What is the function of this protein?
Thionins are small plant proteins which are toxic to animal cells.  They seem to exert their toxic effect at the level of the cell membrane.  Their precise function is not known.
What are the official names of this protein?
Alpha-2-purothionin.
What is the protein family that this protein belongs to?
Belongs to the plant thionin (TC 1.C.44) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NPD1_STRCO
Sequence: MRMRPTLSWTPGADLPPGTTDLAPVADALRAGGVLVLSGAGISTESGIPDYRGEGGSLSRHTPMTYQDFTAHPEARRRYWARSHLGWRTFGRARPNAGHRSVAAFGRHGLLTGVITQNVDGLHQAAGSEGVVELHGSLDRVVCLSCGVLSPRRELARRLEEANAGFSPVAAGINPDGDADLTDEQVGDFRVVPCAVCGGVLKPDVVFFGENVPPRRVEHCRELVRGASSLLVLGSSLTVMSGLRFVRQAAEAGKPVLIVNRDATRGDRLAVTRVALPLGPALTTVADRLGLRVGDAATA
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase 1, Regulatory protein SIR2 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGB_ECOLI
Sequence: MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDIDFASELKKVMQRGRDATSVVALTMTSTQHIPAQALTPPTAELQYRIPDQPSLDGNTVDMDRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN
What is the function of this protein?
Structural component of flagellum, the bacterial motility apparatus.  Part of the rod structure of flagellar basal body (By similarity).
What are the official names of this protein?
Flagellar basal body rod protein FlgB, Putative proximal rod protein.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: ISPF_YERPE
Sequence: MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RF2_CHLAB
Sequence: MHESLDKRLEGLLTGLALAGRSLDLEGKRQELSILEEQTLKEDFWQDVTSAGKVSERIVSLKRQIAHYEEFKVRVENLAFFLNDGDVSADPELREDLEKEFTICEHILSEWETQRLLSGEVDKNPCFLTINAGAGGTESCDWVEMLFRMYCRWAAQHQWKVEVIDRQEGDVAGIKHVTVKFSGDYAYGYAKAERGVHRLVRISPFDSNAKRHTSFASVDVYPEIDDEIEIDIRPNDLRIDTFRSSGAGGQHVNVTDSAVRITHIPTGIMVSCQRERSQIQNRESCMKMLRARMYQQILQERLEKQLLDRKNKKEIAWGSQIRNYVFQPYTLVKDVRTGHETGNVQAMMDGELLDDFVKAYLAEYGEIS
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_PELUB
Sequence: MARVTVEDCIDKVESPYELVLVAKERAVQLNSGLEPTLDRDNDKNTVISLREIAADTIKVSDLTDSAIHKLRKHVEQVDDGTDDDEIIGDDFESMYKGEISKSGTPILPSKRARKIPEKIQVSSDDLEELTAKAEPEVDVDAELEVGDEETAVSLDQIAEAETEAETTEVNSDDSETTNS
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PWP2_DICDI
Sequence: MKFGYKFSNLLGTVYNKGNILFTPDGNTVISPVGNRLTVFDLVNHTSITLPIQSKYNIRRLALSPNGQILITSDESGHTLIINLTRQVVLGEYKFFKTPKSILFSPNGAIIAIAVLEKVFLFKTPIIQKQPNPLIRLSVFTHKSAVISMCWSADSLKLMIGCKNGTLLIRQGKSERVSYFQVKGSGIINCFFGNEESTIAYAVTPTGLASWDYKTNEEMEQEKLERVENGETAYLREEEMDEEKLKVITENQRLYKGRWIFKGFKKFENYGVKCKVKTVCFHLKSKLLLVGFSTGQFILYEMPGFNQLYKLNISSHGISTSAINNTGEWLAFGCSELGQLLVWEWRSETYILKQQGHSYNMNTVAYSPDGQTIATGGEDGKVKIWNTTSGYCYITFTEHEGPVTAVKYSPVSSQNVVFSAGVDGTIRAFDLVRYRNFRTFVSPNKTQFSCLAVDPSGEIIAAGSLDSFEIYVWSVRTGRLTDILSGHQSPVCELAFDPINPFLASASWDKSCKIWNIFEDREIRESIQHTSDVLTCAYSQDGKKFIVSCLDGTIQIYETSTWGQIGLIDGKNDIMGGRGYKDEILAKNNSAGRAFTKIAFTPNGECIIAGGNSKYICIYHIDQQVLIKKYSTSSNLSLDGITLDINWKRVGEFGHLDAMEKDFDSDDDLYQQNKEYLTGSSKGDLSKRTTKKKQKTTSISVSPTGRAWAVSTTEGLLIYSLDDFLFFDPTDLSIDINPDSILSELNLKNYLKSLIMSIKLNEKPIIEKVFESIPFNEIQLVCQEFPIYYLKNFIQFLSGYFEKNHHLEFQMKWVKLISIYHGKYIKTNSLSMITSLRNLQKTITQTYNDISKVCDDNIFSMEYFKTVLLKELKSQEETNKISKKSQKYKKYLESKKNKEQEEDQFSDDEETVYQNNKKNKNK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Periodic tryptophan protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PWP2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y2003_BURPS
Sequence: MADPQLITTAFDIPGYRIERSLGVARGIVVRSRSIVGTFGASIQTLFGGNISLYTSLCERARQDAYERMIDEARRMGGNAIVGMRYDATEIASGVTEVLCYGTAVQAVRAG
What are the official names of this protein?
UPF0145 protein BPSL2003.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: CLPX_BRUMB
Sequence: MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVIGQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDALVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVERKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDVVDGSARPLYIYAERQDEKGNVSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SYM_SALPC
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSDENRELSELIYTRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSADQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDTTSFDEYWKKDSDAELYHFIGKDIVYFHSLFWPAMLEGSHFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLKHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLAAELADPQLYKTFTDAAAVIGEAWESREFGKAIREIMALADVANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPTLSERVEAFLNSELNWDAIEQPLLSHKVNTFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADFPIQETITFDDFAKIDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSSYPDPQALIGRQTVMVANLAPRKMRFGVSEGMVMAAGPGGKDIFLLSPDDGAKPGQQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_SYNJA
Sequence: MARDYYEILGVSRDSSKEEIKRAYRRLARKYHPDVNKEPGAEDRFKEINRAYEVLSDDELRARYDRFGEAGLSGAAAAASGFQDFAGIGGFADLFESFFTNFAGGGVGYSRSRQGPVRGDDLRFDLKLEFLEAIFGGEKQIRISHLEVCPVCGGSGAKPGTDVKVCPTCGGAGQVRRATRTPFGNFTQVSICPTCGGAGRVLEEPCYNCNGEGLAQTTKKLRINIPAGVDSGTRLRVSGEGDAGRRGGPPGDLYVYLFVEPDPDFQRDGLTIFSQVRVSYLQAILGAKVLVPTVDSKAGLEEEAELTIPAGSQPGTVLTLEGKGVPRLGNPMLRGDHKITLVVEIPTRISSEERELLMRLAELHGERINKRDGFLGGLLRGLAQMPGNREREEE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVHG_METTM
Sequence: MAEKIKIGTMWLGGCSGCHLSIADFHEKLLDVMEHADFEFSPVLMDTKYDEIPELDVVVIEGGIVNDENREFAEELREKAKFVISYGTCAVYGGIPGLRNLWDKDEVIEEAYINSITTPNEEGVIPSEDVPHLEGRVKPLGEVIDVDFEVPGCPPRSDVAAEVVMALLKGEEIELPSTNLCEVCPREKPPEGLAMDFIKRQFEVGKPEDDLCLIPQGLICMGPATVSICGAECPSIAIPCRGCYGPTARVEDQGAKMISAIASDYKVEEDKTVDPEEVAEQLDDIVGTFYTFTLPAALIPMKIKKEGK
What is the function of this protein?
Part of a complex that provides reducing equivalents for heterodisulfide reductase.
What are the official names of this protein?
F420-non-reducing hydrogenase subunit G, Methyl viologen-reducing hydrogenase subunit gamma, MVH subunit G.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
Protein: FHOD3_MOUSE
Sequence: MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLAGVHRLLRAPHKLDDCTLQLSHNGAYLDLEATLAEQRDELEGFQDDTGRGKKNSIILRTQLSVRVHACIEKLYNSSGRDLRRALFSLKQIFQDDKDLVHEFVIAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGVINHSETIQWLYTLVGSKFRLVVKTALKLLLVFVEYSESNAPLLIQAVSAVDTKRGVKPWSNIMEILEEKDGVDTELLVYAMTLVNKTLAGLPDQDTFYDVVDCLEELGIAAVSQRHLNKKGTDLDLLEQFNIYEVALRHEDGDETAEPPPSGHRDRRRASMCSGGTVGEQQGLDRRRSRRHSIQNIKSPLSAPTSPCSPSVPAFKPSQVRDLCEKDEEEEEEEEQPITEPNSEEEREDDAQCQGKDSKASSASGQSSPGKDAAPESSALHTTSSPTSQGRWLSASTAARSPVLGGTSGPEASRPAARLLPPSPGLATRPSTAPKVSPTIDKLPYVPHSPFHLFSYDFEDSPLLTKDKGGDSQTENRYSNFSSNSFQSSRPSPGPSGSPSYASSFSSPQDTRSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFNREYLDKREEQRQARGERYKYLEQLAAETQEKEPRSQSVSRGRADLSLDLSLPAAPAPPSPSSQSPSADSQEALPVPSSPPTLQCPQVSGKDHEPELEAEAGQGADEASQDIASAHRGAESQEEPVLELEPEERASLSEKERQNEEVNERDNCSASSISSSSSTLEREEKEDKLSEDRATGLWSTSLQDVGVNGQCGDILTSKRFMLDMLYAHNRKSTEDEEKDDGEPGRSAQEVEAVASLATRISTLQANSQAPEESIKRVDIGCLDNRGSVKAFAEKFNSGEVGRGAISPDVESQDKVPDTPPAQLKTESDYIWDQLMANPRELRIQDMDFTDLGEEDDIDVLDVDLGHREAPGPPPPPPPTFLGLPPPPPPPLLDSVPPPPVPGNLLASPVFNTPQGLGWSQVPRGQPAFTKKKKTIRLFWNEVRPFEWPSKNNRRCREFLWSKLEPIKVDTSRLEHLFESKSKELSVTKKTAADGKRQEIIVLDSKRSNAINIGLTVLPPPRTIKIAILNFDEYALNKEGIEKILTMIPTEEEKQKIQEAQLANPEVPLGSAEQFLLTLSSISELSARLHLWAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTNAKAFELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFDQLQDNLCQMERRCKASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRIINRFHSFLLFMGHPPYAIREVNINKFCRIISEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITDSGKFSGSSPAAPSQPQGLSYAEDAAEHENMKAVLKTSSPALEDATPVLGVRTRSRASRGSTSSWTMGTEESPSVTDDAADEIMDRIVKSATQVPSQRVVPRERKRSRANRKSLRRTLKSGLTPEEARALGLVGTSELQL
What is the function of this protein?
May play a role in actin filament polymerization in cardiomyocytes (By similarity).  Actin-organizing protein that may cause stress fiber formation together with cell elongation.
What are the official names of this protein?
FH1/FH2 domain-containing protein 3, Formin homolog overexpressed in spleen 2, mFHOS2.
What is the protein family that this protein belongs to?
Belongs to the formin homology family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Note=Main part of the protein localizes to actin fibers and the remaining part displays filamentous staining.
Protein: DF225_ARATH
Sequence: MKYGVLFMVSCGVMFLILSHVEEVEAMKKFGCNTTHPFPGKCGNNGKSSWVSDMKKLPSAPKNRDIRCECSDRPSLARGMPGERVCRCDYDC
What are the official names of this protein?
Putative defensin-like protein 225, Putative S locus cysteine-rich-like protein 1, Protein SCRL1, SCR-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: M1_I61A1
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTCPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKLKREITFHGAKEVALSYSAGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: Y1526_SYNY3
Sequence: MTWNEGYVLEVNYTYGFYGELSPLKLALANTLKSLKSPNLEKNFNYCELACGRGYSTNLLASCYPQAQFYANDFNPSHIVEARTLAETAGTKNVHFFDDSFEEFINQDLPQFDFIVLHGIYSWITPRNRQAIVNFIRQKIKVGGMVYISYNTLPGWAAARPMQALMLRYGRNSSEPILSRIEKALDFTEQMLESKANYFTQNPILKPRLEKLKEQNRYYLAHEYFNEEWNAFYFDEVAKELEEAKLNFMGSAHLIDYVDAVNLSSAAQTQLSQVTDPTFREVVRDFFLNTQFRRDIFVRGKLALLPQEHLQALGNLRFALVVPIKSIKLKQQFPLGEVELQEKVYRPICEALENGPLTLGELQKDSKTKGITLNSLYQALIIMTGIGYTHPAVNETVRKQRQKSTDAFNSAVKTKSLYSDEMAFLASPLVGTGIAVNRLEQLLLLAKERKQDGPQFVWQVLSSQGKKIIKEGKTLETEAENLEHLKNVAENFNGDRLPLLTKLGIS
What are the official names of this protein?
Uncharacterized protein sll1526.
What is the protein family that this protein belongs to?
To R.prowazekii RP789, RP027 and RP028.