PharMolix/UniProtQA huggingface dataset:
Protein: DCD_XANOM
Sequence: MSIKSDRWIKRMAEQHAMIAPFEPGQIKHDAAGQRIVSFGTSSYGYDVRCSREFKIFTNINSTIVDPKRFDPGSFVDVESDVCIIPPNSFALARTVEYFRIPRDTLVVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPARIYANEGVAQMLFFQSDEVCETSYKDRGGKYQGQTGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: SWT12_ORYSI
Sequence: MVQALVFAVGIVGNILSFLVILAPVPTFYRVYKKKSTESFQSVPYAVALLSAMLWLYYALLTSDLLLLSINSIGCLVESLYLTVYLLYAPRQAMAFTLKLVCAMNLALFAAVVAALQLLVKATDRRVTLAGGIGASFALAVFVAPLTIIRQVIRTKSVEFMPFWLSFFLTLSAVVWFFYGLLMKDFFVATPNVLGLLFGLAQMVLYVVYKDPKKNSAVSEAAAAQQVEVKDQQQLQMQLQASPAVAPLDVDADADADLEAAAPATPQRPADDDAIDHRSVVVDIPPPPQPPPALPAVEVA
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET12, OsSWEET12.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BOL3_YEAST
Sequence: MKLPQTMLRSISVKHVRWPRILTGSKLWYSTQMAMTPEEKMITDKLQQELEPEVCKVQDVSGGCGSMFAINITSKKFNGLSLIKQHQLVNRILRDDISRWHGLQLTTKKSTGKGPASS
What is the function of this protein?
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates [4Fe-4S] cluster insertion into a subset of mitochondrial proteins such as lipoyl synthase (LS) and succinate dehydrogenase (SDH) (PubMed:27532773, PubMed:27532772).  Required during the last step of iron-sulfur protein assembly when the iron-sulfur cluster is inserted into the target protein (PubMed:27532772).  Acts together with NFU1, later than BOL1 and GRX5 in the [4Fe-4S] cluster insertion process (PubMed:27532773).  Not required for [2Fe-2S] cluster insertion into mitochondrial proteins (PubMed:27532772).
What are the official names of this protein?
BolA-like protein 3, Altered inheritance of mitochondria protein 1.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RS8_GRIJA
Sequence: MGISRDSRHKRRLTGGKHPYTCKKRKYELGRQPAMTKIGGKLVRTVRVRGGNLKSRALRLESGNFAWGSEAFTSKSRILNVVYNASNNELVRTNTFVKGCIIQIDATPFRQYYHNHYGIDIGKKKAGDEESKFSKRHAGKQEKRCQTRLPLDEGIKELFQSGRLYASIASRPGQSGRADGYLLEGKELEFYAKAMQKKKKAGKS
What are the official names of this protein?
40S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: ERB1_PYRTR
Sequence: MSVNPRKRKVVTRPAPEPSDSEGELGDGLLEGILSHSEDDSDNSREEEVDTDASSVIEGLSDEDEEEDEDSDSEQIRTEMRNLNTSDGPLRKKKGVPTHDMDLDTAVTEELEDDEDLKPNYTVTTDAHGNTRYIYKEIDPVYESDDSDVEATNTIGNIDLKYYDEYPHIGYDINGKKIMRPAKGEALDALLDSIDIPKGWTGLTDPQTGKPLNLSEEELDVLKRLTRNEVVEDGYDPYPEMVAYFSGKQEIMPLSAAPEPKRRFIPSKHEAKRVMKLVKAIREGRIQPYRAPEEQEEEQDAFNFDVWADEKPRPDNSMHIPAPKLPPPGYEASYHPPPEYLPDKAEEQAWLEADEEDREREFLPKNYDALRKVPGYETFVKERFERSLDLYLAPRIRRNRLNIDPESLLPKLPNPEDLKPFPTTCAAIFRGQEGRVRCVSIDPNGIFVASGGDDGYVRIWELLTGRQVWNAKLSDEEAVDAVQWRPKKDASVVAAACGENVFLIVPFTLLSPDVEQASREVLDAGWGYATSKPSTSSNGEAPKQAPGKWSRPGARLENKGVLVQVEVRSAVKIVNWHRRGDYFATVSPRGQSTAVAIHTVSKHLTQLPFRRLKGIAQTAQFHPSKAIFFVATRNTIRSYDLAKQELVKILQPGAKWISSIDVHPGGDNLIVGTYDKRLLWHDLDLSNKPYKTLRFHKEAIRAVRFHQGGLPLFADTSDDGTIQIFHGKVVGDLMENATIVPLKVLKGHKVRSRLGVMGLDWHPKEPWCVSAGADGTLRLWS
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein erb1, Eukaryotic ribosome biogenesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: NRAM_I68A6
Sequence: MNPNQKIITIGSVSLTIATVCFLMQTAILVTTVTLHFKQYECDSPASNQVMPCEPIIIERNITEIVYLNNTTIEKEICPKVVEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDHGKCYQFALGQGTTLDNKHSNDTIHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLSGSAQHVEECSCYPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDRSSNSNCRNPNNERGNQGVKGWAFDNGDDVWMGRTISKDLRSGYETFKVIGGWSTPNSKSQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGRKQEARVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: STPG1_MOUSE
Sequence: MSQKFANLDNVVLRADLDKPKKHADRVQKGFTAAYPTQSSIPYRHRTSIIPESEKKGFNSQARRFYSKKDDVPGPGFYNVIHQSPVFSSASLSKRGTCTFPSTCARLGPIISKNPAANAYTIRSDLASKKDFSNSCSSMFQLPSFMKVEKSETPAPNHYNASIASCRQKNNVCARAGFLSKTPRGFIPSSASGGPAPGHYNVNESLVRQSPKFLMSCFKSRTGRGLKPTSIGPGPGYYNPNDQTKILKKSYFPKTTLLNFSAHPLPLPPKPPLPGPGQYEIVNYEGPPKHFISSASFVSNTSRWPMKSSKPNLPGPATYKPEIPGKQSFLYNEDNKWVPAV
What is the function of this protein?
May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.
What are the official names of this protein?
O(6)-methylguanine-induced apoptosis 2, MAPO2, Sperm-tail PG-rich repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the STPG1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RF1_STAA3
Sequence: MFDQLDIVEERYEQLNELLSDPDVVNDSDKLRKYSKEQADLQKTVDVYRNYKAKKEELADIEEMLSETDDKEEVEMLKEESNGIKAELPNLEEELKILLIPKDPNDDKDVIVEIRAAAGGDEAAIFAGDLMRMYSKYAESQGFKTEIVEASESDHGGYKEISFSVSGNGAYSKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEVEDVEIEIRNEDLKIDTYRSSGAGGQHVNTTDSAVRITHLPTGVIATSSEKSQIQNREKAMKVLKARLYDMKVQEEQQKYASQRKSAVGTGDRSERIRTYNYPQSRVTDHRIGLTLQKLGQIMEGHLEEIIDALTLSEQTDKLKELNNGEL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BET5_YEAST
Sequence: MGIYSFWIFDRHCNCIFDREWTLASNSASGTINSKQNEEDAKLLYGMIFSLRSITQKLSKGSVKNDIRSISTGKYRVHTYCTASGLWFVLLSDFKQQSYTQVLQYIYSHIYVKYVSNNLLSPYDFAENENEMRGQGTRKITNRNFISVLESFLAPMVNQ
What is the function of this protein?
Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1.  TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.  TRAPP II plays a role in intra-Golgi transport.  TRAPP III plays a role in autophagosome formation.  Required for sporulation.  Has a role late in meiosis following DNA replication.
What are the official names of this protein?
Trafficking protein particle complex subunit BET5, TRAPP subunit BET5, Transport protein particle 18 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET5 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum. Preautophagosomal structure.
Protein: T2R60_HUMAN
Sequence: MNGDHMVLGSSVTDKKAIILVTILLLLRLVAIAGNGFITAALGVEWVLRRMLLPCDKLLVSLGASRFCLQSVVMGKTIYVFLHPMAFPYNPVLQFLAFQWDFLNAATLWSSTWLSVFYCVKIATFTHPVFFWLKHKLSGWLPWMLFSSVGLSSFTTILFFIGNHRMYQNYLRNHLQPWNVTGDSIRSYCEKFYLFPLKMITWTMPTAVFFICMILLITSLGRHRKKALLTTSGFREPSVQAHIKALLALLSFAMLFISYFLSLVFSAAGIFPPLDFKFWVWESVIYLCAAVHPIILLFSNCRLRAVLKSRRSSRCGTP
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 60, T2R60, Taste receptor type 2 member 56, T2R56.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FABH_ROSCS
Sequence: MANFAAITGWGMAVPERVLTNADLERMVETSDEWIQTRTGIRERRIAGPGEHTSALSIAAGRAALARAGLDAAQIDTVILATCTPDRPFPATACTVQAGVGARRAAAFDIVAACSGFVYGLQVATSMVRSGAARNVLFVACDIFTHFINWNDRNTCVLFGDGAGAVVLQPSDEPAGLLSCVLGADGEQEDLMAVDAGGTRLPATPELLEEGRQYVFMNGREIFKHAVREMAASSFDALQAAGLSTDDVALVIPHQANLRIIEATAKRLEVPLDRVFVNLDRYGNTSAASIPIALVEAVEQQRLRKGDYALLTSFGGGLTWASAVIRWSAG
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_RUTMC
Sequence: MNSEYNAQKIEAQAQKYWQENKSFEVSEDTSKEKYYCLSMFPYPSGSLHMGHVRNYSIGDVISRYQKMQGKNVMQPIGWDGFGLPAENAALENKVSPAKWTYENIDYMRDQLSKLGFGYDWSREIATCHQKYYRWEQWLFIKLFEKDLVYKKNAIVNWDPVDQTVLANEQVIDGRGWRSNALIEKKKISQWFMRITNYADELIYGLDKLDGWPDAVKTMQKNWIGKSVGLEVDFPRHNADSIKVYTTRPDTLMGVTYLVISSEHPIALEAGKNNPQVQAFIDECKTIQITKETMKTIDKKGIDLGVKCIHPITSDDVPIWIANFVLIGYGTGAVMSVPAHDKRDYEFAKKYGIAIKKVINENISIDKNAMTDKGVLFNSGEFNGLNFDQAFNEIAKTLTDKNLGRKKTNYRLQDWGISRQRYWGCPIPIINCQNCGIVVVPEADLPVVLPEVMSFDSVGSLIKKMPEFYQTTCPKCGKMAQQETDTLDTFFESSWYFARYTCKDNNDKMLDKRANYWLANGGVDQYIGGIEHAILHLLYARFFNKLLRDEGFIKNDEPFKNLLTQGMVLKDGAKMSKSKGNTVDPAQMIEKYGADTVRLFILFAAPPTQNLEWSDSGLEGVHRFINKVYRLIMDFIQDHKSHAIGTLNNFDKAQKDIRLKTHQTLSKITDNMSRRYLFNTVIAALMKLCNTLSKFNDTSKTSMAIRQESIHILLKTLSPIAPHLCHYLWKKLGNIKAIINEPWPNVDKSALVQDKMQIIVQVNGKLRTKLMFSTDVDNAQIEAQTLANENITKFTKGKIIVKVIIVPNKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS6_LEMGI
Sequence: MASSMMASTAAVARVGPAQTNMVAPFNGLRSSVAFPATRKANNDLSTLPSNGGRVSCMQVWPPEGLKKFETLSYLPPLSVEDLAKEVDYLLRNDWVPCIEFSKEGFVYRENHASPGYYDGRYWTMWKLPMFGCTDASQVIAEVEEAKKAYPEYFVRIIGFDNKRQVQCISFIAYKPT
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 6, RuBisCO small subunit 6, RuBisCO small subunit SSU5B.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ILVC_VESOH
Sequence: MNIYYDKNADLNIIKDMKVAIVGYGSQGHAHANNLRDSNVEVVVALRDGSASSKKASDAGLNVKSIKQATAWADLIMVLAPDEFQAQIYTDSIEPNLKQGATLAFAHGFNIHYNRIIPRADLDVIMIAPKAPGHTVRSEFVKGGGIPDLIAVFQDVSGNAKDTALSYASAIGGGRTGILETSFKDETETDLFGEQVVLCGGTTALVQAGFETLVEAGYEPEMAYFECLHELKLIVDLMYEGGIANMRYSISNTAEYGDITRGSRIVTADTKDEMKKILIEIQNGVFAKEFVANVGELPAHREVQRAHQIEQVGESLRSMMPWINKNKIVDQSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RL28_COXBU
Sequence: MAKVCQVTGKRPQSGNNVSHANKKTNRRFLPNLKKRRFWLPDEKRFITLTVSTHGMRIIDKLGINAVLKKIREREKESK
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DCD_ANAMF
Sequence: MSAMPDHWIKEKALKEGMISPFVDHKEEAGVLSYGLSSYGYDARVDSKFKIFANTHSSIVDPKNFPQDSFIDKETDVCIMPPNSFMLAKTVEYFRIPKDVIVICVGKSTYARCGIVVSVTPLEPGWEGYVTLEFSNTAPLPVKVYAFEGACQFIFLAGNERCSISYDQVNGKYMRQGGVTLPIVS
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: IF2A_SULTO
Sequence: MIYNKNPIPTEGEILIATVKQIFDYGSYVTLDEYGNLQAFLPWSEISSRWVKNIRDVIKEGRKIVVKVIRVDKRKGTIDVSLKKVTEDEKRKKMSQWKKIQKVDKILEIVSQKINKTEKEGWEQVAWKLEDKYGDAYDALVKAVKEGDSILKNAGVPEVWIKPLMEEIGKHIEEKRVKKSEIVTLRSSDPAGIEKIRKVLGAAVEIAENADVDIKIYTIGAPRYRIDIIGTDPKLLSKVMTEILDNIREISKEEKVEFNVVRK
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit alpha, aIF2-alpha, eIF-2-alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
Protein: UBF1A_XENLA
Sequence: MNGAAGGVTQAKMTAPKDQDPWSQDEMLTLIQTMKTLLPSQDNSKFKTTESHLDWNKLAFKNYSGSMCRQKWMEISNEVRKFRTLSELILDAEEHVRHPYKGKKLKKHPEFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKLEFERNLARFREEHPDLMQNPKKSDVPEKPKTPQQLWYNHERKVYLKLHADASTKDVKDALGKQWSQLTDKKRLKWIHKALEQRKQYEGIMREYMQKHPELNIAEEGITRSTLTKAERQLKDKFDGRPTKPPPNSYSMYCAELMANMKDVPSTERMVLCSQRWKLLSQKEKDAYNKKCEQRKKDYEVELMRFLESLPEEEQQRVLAEEKMVRSRSGQADKKKAADERAKLPETPKTAEEIWQQSVIGDYLARFKNDRAKALKSMEGTWLNMEKKEKIMWIKKAAEDQKRYERELSDMRATPTPTTAGKKVKFLGEPKKAPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWHRISPSQKDYYKKLAEDQQRVYRTQFDTWMKGLSSQDRAAYKEQNSNKRKSTAKIQVPVAKPKLVAQSKSDDDDEDDDDDEDEDDDDDEDEDKEDSSEDGDSSESSSDEDSEDGEENEDEEGEEDEDEEEDDDDNESGSSSSSSSSADSSDSDSN
What is the function of this protein?
UBF recognizes the ribosomal RNA gene promotor and activates transcription mediated by RNA polymerase I through cooperative interactions with the species-specific factor SL1.  It binds specifically to the upstream control element.
What are the official names of this protein?
Nucleolar transcription factor 1-A, Upstream-binding factor 1-A, UBF-1-A, xUBF-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPP_BORPA
Sequence: MPVHEIRHPLIRHKLGIMRRADLSTKSFRELSQEVAALLTYEATKDMPLAPASVEGWCGTVEVDKIAGKKVTVVPILRAGIGMLDGVLSLIPGAKVSVVGVARNEETLQAHTYLERLVGELDQRLALIVDPMLATGGSMVAAIDMLKRAGCREIRALTLVSAPEGIDAVLTAHPDVQIYTASIDQGLNENGYIMPGLGDAGDRIFGTTQKHAE
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: PAND_YERPP
Sequence: MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLEAAGILEYEAIDIYNVDNGQRFSTYAIAAERGSRIISVNGAAARCACVGDKLIICSYVQMSYAAARLHHPKVAYFEGENQLQRKAKAVPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_DESHD
Sequence: MAKQIVFNEEARRALERGVNALAESVRVTLGPKGRNVVLDKKFGAPLITNDGVTIAREIELEDPFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREGLKNVAAGANPMGIKRGIEKAVESVVEDIKTNAKPIESKESIAQVASISAGDDNIGVLISDAMEKVGKDGVITVEEAKGMTTELKVVEGMQFDRGYLSAYMITDTDKMEAILNDPYILITDKKIGAIADILPVLEKVVQAGRQLLIIAEDIEGEALATLILNKLRGTFTCVAVKAPGFGDRRKAMLEDIAILTGGTVITEDLGLKLENTTIDMLGRARQIRVTKEETTIVEGSGSQDDIKSRVEAIKKQIDETTSDFDREKLQERLAKLAGGVAVIQVGAATEVEMKEKKLRIEDALAATRAAVEEGIVAGGGCALVDAAKALDSLKLTGDEKTGVAIVCRALEEPLRQIANNAGFEGSIVVEKVRNGGRGVGFNALTEAYEDMIAAGIVDPAKVTRSALQNAASIAAMLLTTECLVSDIPSKDNGAAAMAGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MES2_ARATH
Sequence: MSEEKRKQHFVLVHGACHGAWCWYKVKPLLEALGHRVTALDLAASGIDTTRSITDISTCEQYSEPLMQLMTSLPNDEKVVLVGHSFGGLSLALAMDKFPDKISVSVFVTAFMPDTKHSPSFVEEKFASSMTPEGWMGSELETYGSDNSGLSVFFSTDFMKHRLYQLSPVEDLELGLLLKRPSSLFINELSKMENFSEKGYGSVPRAYIVCKEDNIISEDHQRWMIHNYPANLVIEMEETDHMPMFCKPQLLSDHLLAIADNFC
What is the function of this protein?
Methylesterase shown to have carboxylesterase activity, methyl indole-3-acetic acid (MeIAA) esterase activity, methyl salicylate (MeSA) esterase activity and methyl jasmonate (MeJA) esterase activity in vitro.
What are the official names of this protein?
Methylesterase 2, AtMES2, Protein METHYLESTERASE 8, AtME8.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Methylesterase family.
Protein: PHS_PARXL
Sequence: MIHKLTSEERATQIAALHGWQAATGRDAIQRQFKFADFNEAFGFMTRVAIKAQEMDHHPEWFNVYDKVEITLSTHEANGVTERDIRLAAFIDSITA
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: SHAKB_ANOGA
Sequence: MLDIFRGLKSLVKISHVNTDSPVFRLHYSITVIILMSFSLIVTTRQYVGNPIDCVHTKDIPADVLNTYCWIHSTFALKSLFLKEVGKDVPYPGVGNSAEATAADKKIYKYYQWVCFCLFFQAILFYTPRWLWKSWEGGKIHALMMDLDIGICSEIEKKQKKKLLLDYLWDNLRYHNWWAYRYYVCEFLSLCNVIGQMFLMNRFFDGEFMTFGLDVITHMEADQEDRMDPMIYIFPRMTKCTFYKYGVSGEVERHDAICILPLNVVNEKIYIFLWFWFIILTILTTLTIFYRIIIIFSPRMRVYLLRLRFRLVRRDAIEIIVRRSKMGDWFLLYRLGENLDSIIFRDVMQDLANRLHNNQHHRVPGMKGEIQDA
What is the function of this protein?
Structural component of the gap junctions at electrical synapses in distal and mid-depth levels in the lamina.
What are the official names of this protein?
Innexin shaking-B.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: DER_ECOLI
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGSPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.  GTPase point mutations (but not a deletion mutant) are suppressed by mild overexpression of RelA, probably due to increased levels of the stringent response mediator (p)ppGpp.  50S subunits assembled in the absence of Der are defective and unable to assemble into 70S ribosomes.  GTPase activity is stimulated by YihI.  Overexpression rescues an rrmJ deletion, stabilizing the 70S ribosome.  Der and RrmJ are likely to share a mechanism to stabilize 50S ribosomal subunits at a very late stage of 50S subunit maturation possibly by interacting with 23S rRNA or 23S rRNA/r-protein complex.
What are the official names of this protein?
GTPase Der, Double era-like domain protein, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.