PharMolix/UniProtQA huggingface dataset:
Protein: SYFA_RHIWR
Sequence: MTTENQDALSEIASAATLADLEAIRVRTLGKSGTITALLKTLGAMTPDQRQAEGPKIHALREAVTAAIADRKASLEGAALEARLATETLDMSLPVSAGMQGSVHPVAQVMDELAEIFADLGFAVATGPEIEDDWHNFTALNIPETHPARAMHDTFYFPDREDGKKMLLRTHTSPVQIRTMMTEKPPIRIIAPGRTYRSDSDATHTPMFHQVEGLVIDRGIHMGHLKWTLETFVKAFFERDDIVLRLRPSFFPFTEPSAEVDVGFTWEKGRRVIGGDPAAGNGGWMEILGSGMVHPRVIANCGLDPDEWQGFAFGCGIDRLAMLKYGMDDLRAFFDGDLRWLRHYGFAALDVPTLSGGVGA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_XANCP
Sequence: MRPAQALIDLDALRHNYRLARQLGGGKALAVVKADAYGHGAVRCAQALEPEADGFAVACIEEALELRQAGVRAPILLLEGFFEHDELALIAEHDLWTVVATPWQVRALAEFRSPRPLRVWLKLDSGMHRLGLSPEDFRAAWLHLRGLPQIDSLVLMTHLAQADELECSRTDEQAVAFALTCGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQPSELTAQLRPVMTVRSRIISVRDLPAGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGKVCPLIGRVSMDMLTVDLTEHPHADVGTPVQLWGDAPQVSTLAAQCNVSAYQLLCGLKRVPRHYSTPAHA
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: Y1739_ARCFU
Sequence: MMFLRLREEIARNLRNSGVRAVSPYKVGIGWIDLAIPRKRIGIDILDGSYESCAERLSSHPFRDVIIVDSVEEFCKEFGIPAPELNDEELEAPSAYVKAIEDALAYLYITGEVYEKEIDYRPLNSTLPDLKRFGYAVSYSKPKLNPQMFVCLTHDGYTAAKKVVLRRVELFEKRLRKLSTPENYIIALGMSAGLKVFKTADLEDYDLKSLLSFMRKLSEERFAVDEALHPKTALCRFLVDTALNGKAVKLAQTLSKLGLAFKVKKYSPFGHYLGEEYRIAREAVEALMKFSFAEIPRDYLREFMALTYPLSHSDIYPILSYSGDFLRKAEESGVCRLEGSKITLSEKFVDYAKVRLAMLIEKITEDLP
What are the official names of this protein?
Uncharacterized protein AF_1739.
Protein: YPV9_METTF
Sequence: MVVKIRRAGNICRLFEEDLSQYRGEYEDCVDYLPEILFLLAELLRSESLEEVDRLKVAAALGYSVSPLDMFPEEIYGPYSFLGDLFVSLTVLRDVVDAIGLNTVENLWRGEVRLFDLLEDCYNRVSKELGAKKKLFLKHVGLDLIG
What are the official names of this protein?
Uncharacterized protein ORF9.
Protein: HEMH_VIBCH
Sequence: MNNHKKLGILLANLGTPQAPTSQAVKAFLSQFLHDQRVVDMSRWLWCPLLHGIILPTRSPKVAKLYQSIWMDEGSPLMVYSRRQRDKLAELSQRPVELGMTYGEPSLLEGVRKLQQQGVEQIVVLPLYPQYSATTTAAVFDGLAKALRQLPVVPELHFIRDYHDHPLYIQALAKSVRASWQQHGQGDLLLCSYHGIPKRYAQNGDIYPEHCLKTTELLAQALGLPQDKVMMTYQSQFGKEEWLQPYTDKTMEALPRQGIKKLDVICPAFSVDCLETLEEIAEQNQEIFLHSGGEAFHYVPCLNDSQSHIELMAALVKVDC
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK29_NEOYE
Sequence: MTFPKISDVTNLDSSSLAEEILVIKRELFDLRLKRATRQDFQPHLFKHSKHRLAQLLTVEKSRTKSTM
What are the official names of this protein?
50S ribosomal protein L29, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARPC2_HUMAN
Sequence: MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR
What is the function of this protein?
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079).  Seems to contact the mother actin filament (PubMed:9230079).  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947).  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 2, Arp2/3 complex 34 kDa subunit, p34-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Synapse, synaptosome. Nucleus.
Protein: RL3_OCEIH
Sequence: MTKGILGRKIGMTQLFSDNGELIPVTVIQAEPNVVLQKKTLENDGYEALQIGFADKKESRTNKAEKGHAEKAGTAPKRYVREIRGAEVNSFEVGQEIKVDIFESGEKIDVTGTSKGKGFQGVIKRHGQQRGPTTHGSHFHRAPGAMGVIDPMRVFKGKKLPGHMGSEQVTIQNLEVVSVDTDKNLLLIKGNVPGAKKSYVKITSAVKGN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CAPP_STRPQ
Sequence: MPLKKLESSNNQTIIAEEVALLKEMLENITRRMIGDDAFTVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVDLAYEINHQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTILELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVMQYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCLSATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRRAFHYIQSRLKQTQIQLTNQPAARMSSSVGLNTSAWSSPASLENPILAYDSPVDFKADLKAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGANIVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGEEVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAAYLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKITFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEMLISASINRMVTQMITDPNEIDSFREIMDSIVADSNTIYRKLVFDNPHFYDYFFEASPIKEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQGNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEWQLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDEKLIHTTINGIATGLRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: NUOI_FRATW
Sequence: MRNITNFLKTFLLWELLKGLKVTGKHFFTRKVTVQYPDEKTPISNRFRGLHALRRYENGEERCIACKLCEVVCPALAITINSTEREDGTRRTSSYEMDLFKCIFCGYCEESCPVDSIVETNILEYHFEERGENIMTKAKLLAIGDKYEAQIAADRLQDKDFR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NAGB_PEDPA
Sequence: MKVIIVKDNVEGGKEGYKLFADAKKNGATTFGLATGSTPITTYQEIIKSDLDFTDSISINLDEYVGLPEDSDQSYDYFMHENLFNAKPFKHSYLPNGRAADLEAEAKHYDQIIEDNPIDLQILGIGRNGHIGFNEPGTPADSTTHKVSLTQSTIDANARFFEHEEDVPRYAISMGLASIMKSKHILIEAYGEDKADAIKGMIEGPVTTDLPASVLQNHDNVTVIIDEAAASKLSNK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: NLE1_SCHPO
Sequence: MATLLPPKSKRQKKESLNPTTIEIPEKFPLVNVQFRASDDSNELASLLVPGNSSVRQLEALLNQLLENSDDPVPYNFALHHEDETIEIQDNLYTSVFHNGLMKTEDHLTLLYTPQAVFRVRAVTRCTASMNGHDGTIISAQFSPSTSSRLVTGSGDFTARLWDCDTQTPIATMKGHTNWVSCVAWAPDASIIATGSMDNTIRFWDPKKGSPIGDALRRHTKPIMALCWQPLHLAPDSGPYLLASGSKDNTVRIWNVKLRTLLFTLSGHTAPITCVRWGGQNWIYSSSYDKTIRIWDAKDGKCLHILKGHAARVNHLSLSTEHVLRSGAYDHTDFKPKSFSDERRKAKERYEACLKQSGERLVSASDDLQLILWDPQKSTKPITKMHGHQKVVNHASFSPDGRCIATASFDSSVRLWDGKTGKFLATLRGHVAAVYQCAWSTDSRLLVSSSQDTTLKVWDVRSKKMKFDLPGHEDQVFAVDWSPDGQRVASGGADKAVRIWSH
What is the function of this protein?
Involved in ribosome biogenesis.  Required for processing and efficient intra-nuclear transport of pre-60S ribosomal subunits.  Interacts with the AAA-ATPase Midasin, which is essential for the ATP-dependent dissociation of a group of nonribosomal factors from the pre-60S particle.
What are the official names of this protein?
Ribosome assembly protein 4, Notchless protein homolog 1, Ribosome biogenesis factor rsa4.
What is the protein family that this protein belongs to?
Belongs to the NLE1/RSA4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SDHL_YEAS8
Sequence: MEMTHYEKTPLIRQVFNNGKTNSWFYVKHEILQPGGSFKSRGIGHLIRKSNEEALSEGSGKLAVFSSSGGNAGLAAATACRSMALNCSVVVPKTTKPRMVKKIQSAGAKVIIHGDHWGEADEYLRHKLMAQESQHGSKTLYVHPFDNETIWEGHSTIVDEIIEQLKENDISLPRVKALVCSVGGGGLFSGIIKGLDRNHLAEKIPVVAVETAGCDVLNKSLKKGSPVTLEKLTSVATSLASPYIASFAFESFNKYGCKSVVLSDQDVLATCLRYADDYNFIVEPACGASLHLCYHPEILEDILEQKIYEDDIVIIIACGGSCMTYEDLVKASSTLNVS
What are the official names of this protein?
L-serine dehydratase, L-serine deaminase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPX2A_XENLA
Sequence: MEDTQDTYSYDAPSIFNFSSFHEDHNADSWFDQVTNAENIPPDQRRLSETSVNTEQNSKVEPVQTTPSKDDVSNSATHVCDVKSQSKRSSRRMSKKHRQKLLVKMKDTHLEKETAPPEYPPCKKLKGSSSKGRHAPVIKSQSTSSHHSMTSPKPKAQLTMPSTPTVLKRRNVLVKAKNSEEQELEKMQELQKEMLENLKKNEHSMKVAITGAGQPVKTFIPVTKPVDFHFKTDDRLKRTANQPEGDGYKAVDFASELRKHPPSPVQVTKGGHTVPKPFNLSKGKRKHEEASDYVSTAEQVIAFYKRTPARYHLRSRQREMEGPSPVKMIKTKLTNPKTPLLQTKGRHRPVTCKSAAELEAEELEMINQYKFKAQELDTRILEGGPVLLKKPLVKEPTKAIGFDLEIEKRIQQREKKEEIEEETFTFHSRPCPSKMLTDVVGVPLKKLLPVTVPQSPAFALKNRVRIPAQEEKQEEMVPVIKATRMPHYGVPFKPKLVEQRQVDVCPFSFCDRDKERQLQKEKRLDELRKDEVPKFKAQPLPQFDNIRLPEKKVKMPTQQEPFDLEIEKRGASKLQRWQQQIQEELKQQKEMVVFKARPNTVVHQEPFVPKKENRSLTESLSGSIVQEGFELATAKRAKERQEFDKCLAETEAQKSLLEEEIRKRREEEEKEEISQLRQELVHKAKPIRKYRAVEVKASDVPLTVPRSPNFSDRFKC
What is the function of this protein?
Spindle assembly factor.  Required for normal assembly of mitotic spindles.  Mediates the binding kif15 and aurka to spindle microtubules.  Required for targeting kif15 to microtubule minus ends.  Activates aurka by promoting its autophosphorylation and protects the phosphorylated residue against dephosphorylation (By similarity).
What are the official names of this protein?
Targeting protein for Xklp2-A.
What is the protein family that this protein belongs to?
Belongs to the TPX2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes during metaphase on spindle microtubules, with a strong enrichment at spindle poles. Localizes to the minus ends of spindle pole and aster microtubules in a dynein- and dynactin-dependent manner.
Protein: Y1030_MYCPA
Sequence: MSGHSKWATTKHKKAVIDARRGKMFARLIKNIEVAARVGGGDPAGNPTLYDAIQKAKKSSVPNENIERARKRGAGEEAGGADWQTITYEGYAPNGVAVLIECLTDNRNRAASEVRVAMTRNGGTMADPGSVSYLFSRKSVVTCEKNGLTEDDILAAVLDAGAEEVEDLGDSFEIICEPTDLVAVRTALQDAGIDYDSAEAGFQPSVTVPLNADGAQKVMRLVDALEDSDDVQDVWTNADIPDEILAQIEE
What are the official names of this protein?
Probable transcriptional regulatory protein MAP_1030.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_MAGSA
Sequence: MAHKKAGGSSRNGRDSAGQRLGVKKFGGELVIPGNIIVRQRGTKFYPGTNVGMGKDHTLFATAMGKVSFKHKAEGRTFVVVEPLPEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CBG_RAT
Sequence: MSLALYTCLLWLCTSGLWTAQASTNESSNSHRGLAPTNVDFAFNLYQRLVALNPDKNTLISPVSISMALAMVSLGSAQTQSLQSLGFNLTETSEAEIHQSFQYLNYLLKQSDTGLEMNMGNAMFLLQKLKLKDSFLADVKQYYESEALAIDFEDWTKASQQINQHVKDKTQGKIEHVFSDLDSPASFILVNYIFLRGIWELPFSPENTREEDFYVNETSTVKVPMMVQSGSIGYFRDSVFPCQLIQMDYVGNGTAFFILPDQGQMDTVIAALSRDTIDRWGKLMTPRQVNLYIPKFSISDTYDLKDMLEDLNIKDLLTNQSDFSGNTKDVPLTLTMVHKAMLQLDEGNVLPNSTNGAPLHLRSEPLDIKFNKPFILLLFDKFTWSSLMMSQVVNPA
What is the function of this protein?
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
What are the official names of this protein?
Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_RHOPA
Sequence: MRPSRRAPDELRAVSLERGVVKYAEGSCLVKFGDTHVLVTATLEERLPPWLKGQGRGWVTAEYGMLPRATLERTRREASAGKQNGRTVEIQRLIGRSLRTIVDLEALGERQITVDCDVLQADGGTRTASITGAWVALADCLNWMKARNMIKGQVLRDNVAAISCGIYNGTPVLDLDYAEDSEAETDANFVMTGDGRLVEVQGTAERTPFSQDEFLQLMALAQKGVARLVDLQKMAVG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: CRCB_SHEON
Sequence: MNNLLLVALGGSIGAVFRYLISIFMIQVFGSSFPFGTLLVNVLGSFLMGVIYALGQMSHISPEFKALIGVGLLGALTTFSTFSNETLLLMQEGDWLKAALNVVLNLSLCLFMVYLGQQLVFSRI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS6_STAAS
Sequence: MRTYEVMYIVRPNIEEDAKKALVERFNGILATEGAEVLEAKDWGKRRLAYEINDFKDGFYNIVRVKSDNNKATDEFQRLAKISDDIIRYMVIREDEDK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: BIN2_MOUSE
Sequence: MAEGKAGGAAGLFAKQMQKKFSRAQEKVLQKLGKTVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEVYSSDWDGHEDLKAIVGNNDLLWEDYEEKLADQALRTMENYVSQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDDAKMAKAEEDFSKAQIVFEDLNQELLEELPILYNSRIGCYVTVFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVQSCAASSPVSPVSPVSPVTSPTSPSATSEPESVSATGEELTSEAGGEDSCESQESLKDEEADEAQSETSSSLPACNGPTPAPASPAAEVGSQEEALSSSAQSPGRGQTGKDTPSPGDVVLRARASSEGAEQSKRAASIQRTSAPPSRPPPPRASGSGSCNAPGSPEGSSQLCSPRASPDASSNPEPAETREKEGAGSSGPEEPRAVSTKSATQASGGLVGLFL
What is the function of this protein?
Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton.  Modulates membrane curvature and mediates membrane tubulation.  Inhibits phagocytosis (By similarity).  Plays a role in podosome formation.
What are the official names of this protein?
Bridging integrator 2.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, podosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cell projection, phagocytic cup. Note=Associates with membranes enriched in phosphoinositides. Detected in the actin-rich cell cortex at the leading edge of migrating cells. Detected at podosomes, at an actin- rich ring-like structure.
Protein: NRDR_YERPP
Sequence: MHCPFCAAVDTKVIDSRLVSDGSQVRRRRQCLDCNERFTTFEVAELVLPRVIKSDEVREPFNEEKLRRGMLKALEKRPVSSDDVETAISHIKSQLRATGEREVPTKMVGNLVMEALKRLDKVAYIRFASVYRSFEDVREFGEEIARLQD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PSTB1_GLOVI
Sequence: MVRNPMASAVESTLKTKAQTSNLSFYYGAIQALKNIHLTLAEHRVTALIGPSGCGKTTYLRCFNRMHDLYPGNRYEGQILLYPDEVNIVGPEVDPIEVRMRVSMVFQKPNPFPKSVYENVAYGLRVRGVRNRAELDEKVERALRQAALWEEVKDRLASLAFNLSGGQQQRLCIARALASEPEIILFDEPTSALDPLATLKIEELMGKLKQSITILIVTHNMQQAARISDFTAFMYLGEVIESGQTNQMFDHPTNQLTEQYVAGHFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CSD_STAAW
Sequence: MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: PHM7_YEAST
Sequence: MADSSSTSAFISTLIIYGLTAVVFVWLFLLLRPKNRRVYEPRSLKDIQTIPEEERTEPVPEGYFGWVEYLLSKPHSFLIQHTSVDGYFLLRYIGIVGSLSFVGCLLLLPILLPVNATNGNNLQGFELLSFSNVTNKNRFYAHVFLSWIFFGLFTYVIYKELYYYVVFRHAMQTTPLYDGLLSSRTVIVTELHKSIAQEGEMQMRFPKASNVAFAYDLSDLQELCKERAKNAAKYEAALNKVLNKCVKMTRNKTQKQLDKLYNNGTKPKDDLETYVPHKKRPKHRLGKLPLCLGGKKVNTLSYSSKRIGELNEEIHEKQADWASNDRQPACFIQFETQLEAQRCYQSVEAILGKKNFGKRLIGYSPEDVNWGSMRLSSKERHSRRAVANTIMVLLIIFWAFPVAVVGIISNVNFLTDKVPFLRFINNMPTFLMGVITGLLPTIALVVLMSLVPPFIVMLGKLSGCVTRQETDLYSQAWYYAFAVIQIFLVVTATSSASSTVDSIIDRPRSAMTLLANNLPKASNFYIMYFILKGLTGPTWTILQAVNLLLSKVLGRVLDSTPRQKWNRYNTLATPRMGIVYPGIEILVCIYICYSIIAPILLFFSTVMLTLLYVAYLYNLNYVFGFSFDLKGRNYPRALFQIFVGIYLSEVCLLGLFIMAKTWGPLVLEVFWIVVTALAHIYMKRKFIPLFDAVPLSAIRHARGEPGYSYPTSDLGLQEIKDIADEMKGKYEQDNTHGILTPVTKDDLKKANLIPDNDGSSENGTPSNPFESGSERASLSGSNAESDSIKKLNDTVIKKSSTLSSSTKDNNESTFVPEGEKFRKFHYSDVEALRNKRPYDEDDHSKHGPEGAVPVNADAGVIYSDPAAVMKEPQAFPPDVLETNTWTRRILQFFNPRRSYPFDSVRMRFPLVFNTSIEYDEEYLSSAYTDPCVREKDPIVWCCKDPLGVSKQQIQEARSNGLDVRDDFTRYDEKGKVIFTYNPPDYEPEAKK
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel.
What are the official names of this protein?
Phosphate metabolism protein 7.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS7_SALPC
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAADNKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: HMUV_BURO1
Sequence: MLTAHHLDVARRHDTILRDLSLSIEPGRVTALLGRNGAGKSTLLKTFAGELTGSVAPHGVRVTGDVTLNGEPLARIDAPRLACLRAVLPQAAQPAFPFSVDEIVLLGRYPHARRSGARHVIAHRDRDIAWRALERAGADALVGRDVTTLSGGELARVQFARVLAQLWPDHDATESGPRYLLLDEPTAALDLAHQHRLLDTVRAVAREWQLGVLAIVHDPNLAARHADTIAMLADGTIVAHGAPRDVMTPAHIAQCYGFAVKMVETGDGTPPVMVPA
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
Protein: COX2_PHYME
Sequence: MTITNYINNQFTFLDMAEPWQLGFQDPATPVMEGIINFHHDLMFFLISIVVFVCWMLFRVITLFDEKKNKIPATVVHGATIEIIWTSIPALILLTVAVPSFALLYSMDEVIDPIITLKVIGSQWYWSYEYSDNLEFSDEPLIFDSYMIQEDDLAIGQFRILEVDNRVVVPTNSHIRVLITASDVLHSWAIPSLGIKLDACPGRLNQTSMFIKREGVFYGQCSEICGVNHGFMPIVVEAVSLEDYLTWLKNKINFDFNVXLIKFYGI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL331_STAES
Sequence: MRVNVTLACTECGDRNYISTKNKRNNPERVEMKKYCSRDNKHTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: GPA10_DICDI
Sequence: MSFLCSENSYQQQSKISIDIDKSLKNHKLKLEEEIRVLIYGQKKVGVTTLFKTFLLMGESQITPEELMDNRNNVYKTIINQLKKFIIISNNSKIELENNNNIQMSNLILELDSENFLWNKEIGETCLKLWNDSGIQKIFQSQFSEFFGYFFKHLQRISDENYTPTPQDLNFIKLTQNGIIEGKFTFERCLIKMIEMGIQTSTLKKWINCFSEVQAIIYVIDLSVYDIVESEDCSKSINKLEKSLNGFKEIIESKYLHGCGVIVFFNKKDIFREKLKTVPFKTYDKDYIGENDFESTTNFIKNKLLDYYSNPNKNVYFLINEESEVDICRSTFNILKDIVLNITYNSVKN
What are the official names of this protein?
Guanine nucleotide-binding protein-like alpha-10 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.