PharMolix/UniProtQA huggingface dataset:
Protein: ATG9_ASPOR
Sequence: MMTSNILSRFLPPNGSPSVYETLRQQDAESNPSDVEERAGLEFEDDRRTQFSDRELEEAMVDAARDGIRSPSPSPSEPFLTQRSPQRTSGTATAKTGGRRRKHSRPRWMHQDPDDGDDDVPPSLLVEGHQDDDEMRSRLPPPPPSHRHPQRELSPAPGPSSRADRARWNTTREQLPLHNDGRGQRPGVIWSLGHPNLASVDPKEKAMWLWANVENLDNFLKDVYTYFLGNGIWSILLNRGLSLLTFAFVVGFSTFLTNCIDYRNFRGSRKMDDILIQQCTKKMSMSSTFLLWLLTVFWIGKAFQYLMDIRRLKHMHDFYYYLLGISDSEIQTISWQEVVSRLMTLRDANPATAGAVSARHRKFMGSQSKQRMDAHDIANRLMRKENYLIALVNKDILDLTLPIPFLRNRQLFSQTLEWNINLCIMDYVFNDQGQVRTLFLKDTHRKALSEGLRRRFIFAGIMNIFVAPFIVVYFLMHYFFRYFNEYKKNPAQIGSRQYTPLAEWKFREFNELWHLFERRVNMSYPFASRYVDQFPKDKTVQVAGFVAFVSGALASVLALVSIIDPELFLGFEITHDRTVLFYLGVFGSVWAFARGLVPEETNVFDPEFALLEVIDFTHYFPNHWKGRLHSDEVRKEFAVLYQMKIVIFLEEILSMIFTPFILWFSLPKCSDRLIDFFREFTVHVDGMGYLCSFAVFDFKKGTNVISQGGTGRRESGRQDLRADYFSTKDGKMLASYYGFLDNYGGNRPANPSSRRQFHPPPAFPTLGSPSAIEMGNIGERLERTQTRHGPAATFMGQQSGLGPGFGAAGFGDHASPAPSILLDPHHQPTASDFRTANRSALYPRFRSSRPVRPITDPIEDDNESPSAEIRRGAVKKSPHTTTGSSGGAIGTSDSNLGESWRMNLIGDELDKDTGEDGENVDEIAGNAGVLGLIQQFQKVSKDNRGRTTVGI
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through atg2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DAPE_NEIMA
Sequence: MTETQSLELAKALISRPSVTPDDRDCQKLLVERLYKIGFAAEELHFGDTKNIWLRRGTKVPVVCFAGHTDVVPTGPVEKWDSPPFEPTERDGRLYGRGAADMKTSIACFVTACERFVAEHPDHQGSIALLITSDEEGDALDGTTKVVDVLKARGELIDYCIVGEPTAVDKLGDMIKNGRRGSLSGNLTVKGKQGHIAYPHLAINPVHTFAPALLELTQEVWDEGNKYFPPTSFQISNINGGTGATNVIPGELNVKFNFRFSTESTEAGLKQRVHAILDKHGVQYDLQWSCSGQPFLTQAGKLTDVARAAIAETCGIEAELSTTGGTSDGRFIKAIAKELIELGPSNATIHQINENVRLDDIPKLSAVYEGILARLLAGNAV
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RHAS_ECO7I
Sequence: MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHGTGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLLPQEQDGQYPSHWRVNHSVLQQVRQLVAQMEQQEEENDLPSTASREILFMQLLLLLRKSSLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQKTGLTPQRYLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGFLQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLB_CYCTA
Sequence: MRLAYWMYAGPAHIGTLRVASSFKNVHAIMHAPLGDDYFNVMRSMLERERDFAPVTISIVDRHVLARGSREKVIENILRKDKEERPDLIILTPTCTSSILQEDLQNFANKASRISDSDVIFANIDHYRVNELQAADRTLEQVVKYYLDRSHGQETLDQSVTDVPSANIIGIFTLGFHNQHDCRELRRLLRDLDIKINQVIPEGGSVKDLINLPRAWFNLVPYREVGLMTAMYLENEFGMPYVSTTPMGAVDMAECIQQIHRNVNTLAPISSNKKVDYEPYIDGQTRFVSRAARFSRSIDCHNLTGKETVVFGDATHAASITKISIREMGIRVSCTGTYCKHDAEWFKEQIQDFCDKILITDDHTEVGDMIARVEPSAIFGTQMERHIGKRLDIPCGVISSPVHIQSFPLGYRPFLGYEGTNQIADPVYNSFALGMEDHLLDIFGGHDTKEIMTRSLSTGIGLIWDPESRRELSKIPHFVRNKVERNIEKFAQQKGIVNITTEVIYAAREVLGI
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PGK_BRADU
Sequence: MANKFRTLDDVDVKGKRVLLRVDLNVPMENGRVTDATRLERVAPTITELADKGGKVILLAHFGRPKGRDAKESLKPVTEALSKVLNKPVAFADDCIGEPAATAVAALKDGDILCLENTRFHKEEEKNDPAFVAELAKLGDIWVNDAFSAAHRAHASTEGLGHKLPAYAGRTMQAELDALEKALGSPTKPVIAIIGGAKVSTKIDLLENLVSKVDALVIGGGMANTFLHAQGVGIGKSLAEKDLAPTALRIIEKAEAANCAIILPVDATVAYHFAANAPSHAYGLDAIPADGMILDVGPQSVARVHAAIDDAATLVWNGPLGAFEMQPFDRGTVAAAKHAAERTKAKKLISIAGGGDTVAALNQAHVAGDFTYVSTAGGAFLEWMEGKPLPGVEVLRIK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_AYWBP
Sequence: MLYFESLKDKFKLNKKQLNKFVFYYEFLKKENQKMNLTSLISLSDVCYKHFYDSLILKEIFDFNNVTNLCDVGSGAGFPSFPLKILYPHLKIIIIESSLKKINFLKQLASHLELDNVCFFHKRVEQHDIAKNGSYDFVVARALARLEIILKWCVPLVKKRGYFIAMKGKNFQQELEASKKIIKQMKVKLVSAKVFELPMQLGTRTNLLFQTE
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H15_HUMAN
Sequence: MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
What is the function of this protein?
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber.  Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers.  Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
What are the official names of this protein?
Histone H1.5, Histone H1a, Histone H1b, Histone H1s-3.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=According to PubMed:15911621 more commonly found in heterochromatin. According to PubMed:10997781 associates with actively transcribed chromatin and not heterochromatin.
Protein: RL24_DEIRA
Sequence: MPRPSAGSHHNDKLHFKKGDTVIVLSGKHKGQTGKVLLALPRDQKVVVEGVNVITKNVKPSMTNPQGGQEQRELALHASKVALVDPETGKATRVRKQIVDGKKVRVAVASGKTID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.  Contacts trigger factor (TF) when it is bound to the ribosome; this contact may expose a hydrophobic crevice in TF (PubMed:16271892).
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SMBT_DROME
Sequence: MNPSELRMMWMSSQYNSERITLEDAATLLGHPTVGLSVMEDLSAHQPTLDMNPMMSLMGGDFTGQAAATAAALGVQPGTLIATNSNNLYGFAHMGGLQQQLLQQSAAAAVFQNYAEAMDNDVENGMVGMAMEAVVDDDDQVYGQRDNNFDDNGSELEPKQEIINIDDFVMMNEDNNSYDGTDFMTSSDKDISQSSSSCMAQMPGSLGVPGVEHDLLVPLPDGLLHHKLLGTTLVPAMGTLNGNAFGNIMVSTENTSSKQMQRTYSTAKGANSTATTATCSASTSSALRSQRKTRKIEPVNRPGLVLKTPIAYRGNIDPSVIPIQKDGMAVCKRCGAIGVKHTFYTKSRRFCSMACARGELYSLVLNTKMEGDQATTSSPDPGAGSESADLPGDQQQSQSDIELDLHAAHIKNANYRFRITDQSKITQLNSFGEPMSMGGDAAANNVQMAADETIAALNGGAVGDATAPGSTEEGASTPNSYLSAAPTPKALRLFKDIYPQDDLPQIPKYERLPVPCPQMEKIISIRRRMYDPTHSYDWLPRLSKENFNAAPVTCFPHAPGCEVWDNLGVGMKVEVENTDCDSIEVIQPGQTPTSFWVATILEIKGYKALMSYEGFDTDSHDFWVNLCNAEVHSVGWCATRGKPLIPPRTIEHKYKDWKDFLVGRLSGARTLPSNFYNKINDSLQSRFRLGLNLECVDKDRISQVRLATVTKIVGKRLFLRYFDSDDGFWCHEDSPIIHPVGWATTVGHNLAAPQDYLERMLAGREAMIEVHEDDATIELFKMNFTFDEYYSDGKTNSFVEGMKLEAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPDASGSDWFCYHEKSPCIFPAGFCSVNNISVTPPNGYDSRTFTWEGYLRDTGAVAAGQHLFHRIIPDHGFEVGMSLECADLMDPRLVCVATVARVVGRLLKVHFDGWTDEYDQWLDCESADIYPVGWCVLVNHKLEGPPRVAHQQAPKPAPKPKIQRKRKPKKGAAGGKTPTDNNTQSVKSRTIALKTTPHLPKLSIKLELKPEHHNAAFYENNQPEEEGDEEDPDADGDGDGSTSHISEQSTTQSSSDLIAGSGSGSGSASLVTLATGSNKTNSSATNNKYIPRLADIDSSEPHLELVPDTWNVYDVSQFLRVNDCTAHCDTFSRNKIDGKRLLQLTKDDIMPLLGMKVGPALKISDLIAQLKCKVNPGRARSHKTNKSPFL
What is the function of this protein?
Polycomb group (PcG) protein that binds to the Polycomb response elements (PREs) found in the regulatory regions of many genes.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility.  Necessary but not sufficient to recruit a functional PcG repressive complex that represses target genes, suggesting that the recruitment of the distinct PRC1 complex is also required to allow a subsequent repression.
What are the official names of this protein?
Polycomb protein Sfmbt, Scm-like with four MBT domain-containing protein 1, dSfmbt.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEU33_ARATH
Sequence: MAAFLQTNIRLEIIPGRYSSLTDHKFRAPYRIRCAAASPVKKRYNITLLPGDGIGPEVISVAKNVLQKAGFLQGLEFDFQEMPFGGAALDLVGVPLPEETSTAAKQSDAILLGAIGGYKWDKNEKHLRPEMGLLNIRRDLNVFANLRPATVLPQLVDASTLKKEVAQGVDMMIVRELTGGIYFGEPRGITINENGEEVGFNTEIYAAHEIDRIARVAFETARKRRGKLCSVDKANVLDASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLGESGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKMIEDAVVDALNKGFRTGDIYSPGNKLVGCKEMGEEVLKSVDSKVPV
What is the function of this protein?
Involved in leucine biosynthesis; catalyzes the oxidative decarboxylation step in leucine biosynthesis (primary metabolism) (PubMed:21697089).  Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate, 3-IPM) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate (PubMed:15849421, PubMed:20840499).
What are the official names of this protein?
3-isopropylmalate dehydrogenase 3, chloroplastic, 3-IPM-DH 3, AtIMDH2, AtIMDH3, IMDH 3, Beta-IPM dehydrogenase 3, Isopropylmalate dehydrogenase 3, AtIMD3.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: EPMA_YERPN
Sequence: MSDTASWQPSAPIANLLKRAAIMAEIRRFFADRGVLEVETPTMSQATVTDIHLVPFETRFVGPGAADGLTLYMMTSPEYHMKRLLAAGSGPIYQLGRSFRNEEAGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQILDCNSAETLSYQQAFLRHLNIDPLSAEKAQLREVAAKLDLSNIADTEEDRDTLLQLLFTVGVEPYIGRDKPAFIYHFPASQASLAEISTEDHRVAERFEVYFKGIELANGFRELTDGDEQLQRFEQDNRNRAKRGLPQNPIDMNLIAALKQGLPDCSGVALGVDRLVMLALNAERLSDVIAFPVNIA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: RS3_YERPA
Sequence: MGQKVHPNGIRLGIVKAWNSTWYANTKEFADNLDSDFKVRQFLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSIISQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SYFA_NOSP7
Sequence: MTSNLEAQLLALRQEGEKAIAAADTLERLEELRVNYLGKKGELGALLRSMGQMSAEERPKIGAIANTVKESLQTSLDQQRVALEAAQIQVQLEAETLDVTMPGIYSPQGRIHPLNGIIDRALDIFVGMGYTVAQGPEMETDYYNFEALNTPPDHPARDMQDTFYLPDGNLLRTHTSSVQIRYMEREEPPIRVVAPGRVYRRDNVDATHSAVFHQIELLAIDEGLTFTDLKGTIKVFLQAIFGDLPIRFRASYFPFTEPSAEVDLQWNGRWLEVMGCGMVDPNVLKSVGYDPEVYTGFAAGFGVERFAMVLHQIDDIRRLYASDLRFLQQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_CHRVO
Sequence: MAWLQATIDSDSAVAERLADALMDAGALSTAIEDAWAGTDKEQPIFGEPGEPVDQLWSQSRIITLFDESADVALLIAAAANACQLAMPAYSVERVEEQDWVRLTQSQFEPIRISDRLWITPTWHEAPAPNAVNLQLDPGLAFGTGSHPTTRLCLQWLDKQLQGNESVLDYGCGSGILAIAALKLGAASAVGIDIDQQAVRASQDNAEQNGVKADFFLPNANPAAQYDVVLANILANPLRMLGDLLASHVKTGGRIVLSGILAEQADELSAIYSQWFEMDPPVFDEGWTRLTGTRRAAV
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAMA_BACP2
Sequence: METKLFSPWTLKGVTLKNRIVMSPMCMYSSYDRDGKLQPFHFTHYISRAQGQAGLIMVEASAVSPEGRISDQDLGIWSDEHIEGFASLNEQIKAYGTKTAIQLAHAGRKAELDGDILAPSSIPFDEQSKTPVQMSVDQIKDTVQAFQDAAVRAKKAGFDIIEIHGAHGYLINEFLSPLANHRTDDYGGSPENRYRFLREVVNAVNEVWDGPLFVRVSASDYTTKGLDIADYIGIATWLKEQGVDLIDVSSGAVVQARISTFPGYQVTFAEKIKEGAGIQTGAVGLITSGVQAEEILRNQRADLIFIGREFLRDPYFPKTAAEELRTSIEGPRQYDRAW
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: SPEB_SALCH
Sequence: MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHHRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLSAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPHHSVQIGIRTEFDKDNGFTVLDACQVNDRGVDDILAQVKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: TEX56_MOUSE
Sequence: MDVDIDPEQLFTEKMPKNYAQPDVLNHTFDLLSNLHKLLPNHLVEVLHSYRSEEDKNKCEKPEFSGLEKILARHQLPKEISLSPKPSLMPSWRRRIINNISGNWKKCHLWQKSTYEPPMGTIVARWTKKNLQPTEDLKSVIQRLSALGPIISVTPSGRQSAVVVFRDITSACKAVSAFQSMSGGSMFQCSWQHRFMAKNKTWSRKCTSKVHLEKRESTVGEPQELHN
What are the official names of this protein?
Testis expressed protein 56.
Protein: MTND_CIOIN
Sequence: MVRAWRILQEETDDPRDALYSDESVSLEQLAQVGVEYFKFDADTFEQNDDYLKLKNNRGYSYSDTISVSRATLPDFDAKIKSFFEEHLHTDDEIRFILDGSGYFDVRDLDGRQLRDCWIRIECVKGDLLVLPSGIYHRFTLDKKDYIKALRLFIGVPVWTPHNRPADSMKERLDYVSKYLTATT
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YHE4_YEAST
Sequence: MSSELLISNSKPRPEGLRKLCEGETVILPRDITPSKCAYFLKQNIVFISYIFIHIIITIILNRLALSAHGNTLIIILAALLITISLFLLLLLPYLSCSRYKLRCLDDDCKFKLLAEVITHKPNMDLSTWDRIAYDMNQFVYDRRICADRSFFYDGSYCYQVFKKLVATPYLVNSNMNSIYADLEMRSNGATNINDSGNSSLHIELGTYIFKALAVFRNSVDKYWEDKYPEMGVTV
What are the official names of this protein?
DUP240 protein YHL044W.
What is the protein family that this protein belongs to?
Belongs to the DUP/COS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLPK_ROSS1
Sequence: MAKYVAAVDQGTTSTRCMIFDHAGRVVAVDQKEHTQIYPQPGWVEHDPLEIWTRTQEVIDGALRKSGVERSEIAAVGVTNQRETTVVWEKATGKPVYNAIVWQDTRTDQICNQLAQDGGQDRFRPKVGLPLATYFSGPKITWILDNVPGVREKAEQGEVLFGNIDTWLIWNMTGGVNGGVHITDVSNASRTMLMNLETLDWDDDILDVMRVPRAMLPKIMPSAAVYGAAVGALEGIPVAGDLGDQQAALFGQTCFSVGEAKNTYGTGCFMLLNTGLKPVPSQNGLLTTVGYKIGDQPTVYCLEGSIAITGALVQWLRDNLRFFDFSSHIEEYANAVEDSGGIYIVPAFSGLFAPYWKSNARGAIVGLTRYITKNHICRAALEATAYQTREVLDAMNKDSGVDLTALKVDGGMVFNNTLMQFQADILGVPVIRPTVSETTALGAAYAAGLAVGFWKEVEDLRANWGKDHEWSPQMDSATRERLYSGWKKAVTRTFDWVD
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: MENC_ECO7I
Sequence: MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELTDALPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLDKVREQVKAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQVQQVRRWPGSPLPLVDVDALERLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: SYDP_IDILO
Sequence: MKTLEESIDALMTRYKENVPVRYTEYVEEWNSPIYGTVIDENTVEWTPCRQPEALNFDDLESALEMSFHQSIKTLFGRWYAGDLALDYQGHTISLLQTQSAEDGERLLENITGHILMKRRLKQPETVFIGLGSEDDGLLVTIDNQSGAVGLEWVGKEQHDVLSDSLAAWLDNCQPQVETDKNS
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: TF3A_HUMAN
Sequence: MDPPAVVAESVSSLTIADAFIAAGESSAPTPPRPALPRRFICSFPDCSANYSKAWKLDAHLCKHTGERPFVCDYEGCGKAFIRDYHLSRHILTHTGEKPFVCAANGCDQKFNTKSNLKKHFERKHENQQKQYICSFEDCKKTFKKHQQLKIHQCQHTNEPLFKCTQEGCGKHFASPSKLKRHAKAHEGYVCQKGCSFVAKTWTELLKHVRETHKEEILCEVCRKTFKRKDYLKQHMKTHAPERDVCRCPREGCGRTYTTVFNLQSHILSFHEESRPFVCEHAGCGKTFAMKQSLTRHAVVHDPDKKKMKLKVKKSREKRSLASHLSGYIPPKRKQGQGLSLCQNGESPNCVEDKMLSTVAVLTLG
What is the function of this protein?
Involved in ribosomal large subunit biogenesis.  Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes.  It is required for their RNA polymerase III-dependent transcription and may also maintain the transcription of other genes (PubMed:24120868).  Also binds the transcribed 5S RNA's (By similarity).
What are the official names of this protein?
Transcription factor IIIA, TFIIIA.
What are the subcellular locations of this protein?
Nucleus.
Protein: V43_BPT3
Sequence: MFKFINTLGKLVVKLYFIEAKKLDKKAKADSQRAIELAKQSREKSDAAVSGVHKSAAIAAKAQSMSKFFE
What are the official names of this protein?
Gene 4.3 protein.
Protein: PUM11_ARATH
Sequence: MDFGFFPGDLRQRGSFTDLGFNGFPLTSSVSNGFHFSGDRTTNPFLNLRKLDTTSLMADGVDMGLCQNLSKMSISDERSNFFNHSSFSGYGCYQGRESSFHGEASSSMRGFVGYGDVHRFEQDLRVRASFHGESAMSSYVGDGSDYHRLRFLALQEASNPNPRCFTENMSLLNRDYMLELEHFNQQIRRDFSLVPQKSPLAFHEERILPPFSAMGGSRELDGSAKCMKNKEDSLDLASMVDSYGSVYLMAKDQLGCRLLQKFVDEGNFVDVMIIFKEVINNVIELGTDPFGNYLIQKLIEVCNEEQRTQILIRLTSKPGLLVKISINNYGTRVVQKLIETVTTKEQISLVKSALVPGFLSLFRELNGNHVILNCLKFFSPNDNKFILEAATKFCIEIATTRHGCCVLQRCVSYSVGEQHEKLVDEISRNSLLLAQDPFGNYLVQYIIEKKVGGVNVLFELRGNYVKLATQKFGSHVVEKCLRYYPESRSQIVNELVSVLNFGYLLQDPYANYVIQCALSKTKGFVRASLVEKVRRYENLKMTPYCKRIFSKNLWKK
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
What are the official names of this protein?
Pumilio homolog 11, APUM-11, AtPUM11.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRF_VIBVU
Sequence: MDIILGVVMFTLIVLALVLVILFAKSKLVPTGDITISINGDADKSIVTSPGGKLLSALAGAGVFVSSACGGGGSCGQCRVKVKSGGGDILPTELDHITKGEAREGERLACQVAVKTDMDIELPEEIFGVKKWECTVISNDNKATFIKELKLQIPDGESVPFRAGGYIQIEAPAHHVKYADFDVPEEYRGDWDKFNLFRYESIVKEDIIRAYSMANYPEEFGIIMLNVRIATPPPNNPDVAPGQMSSYIWSLKEGDKCTISGPFGEFFAKDTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKRKMSYWYGARSKREMFYVEDFDGLAAENDNFVWHCALSDPLPEDNWDGYTGFIHNVLYENYLRDHDAPEDCEYYMCGPPMMNAAVIGMLKNLGVEDENILLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS20_ARTS2
Sequence: MANIKSQKKRILTNEKARLRNNAVKSELKTAIRAVNTAVESTDKDAAAAALVAASRKLDKAVSKGVLHKNNAANRKSAISKKVNAL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.