PharMolix/UniProtQA huggingface dataset:
Protein: RS5_METRJ
Sequence: MAREREGGGRGRREDREERDSEFVDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATEAAKRGLIRVSLREGRTLHHDVNGRHGAGKVILRAAPQGTGIIAGGPMRAVFETLGMQDVVAKSLGSSNPYNLVRATFEALKNEDSPRSVAARRGIKVSTLQSRRRDADPADQSEAAVA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SERC_ECOLU
Sequence: MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAIDETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKALTDFMIEFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PATR_MYCUA
Sequence: MTAHLRPVLAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIEHATQSINRYPDNGCLAVKAALARHVSSLSAADFGPEHIAVGCGSVSLCQQLVQITASVGDEVIFGWRSFELYPPQVQVAGATAIQVPLTNHTFDLEAMLAAVTERTRLIIVCDPNNPTSTVVQPEALAEFVRSVPPHILVAIDEAYVEYLRDGTVPDSPHLVRTHSNVVVLRTFSKAYGLAGLRVGYAVGQPDVIAPLDKVYVPFTVSSLAQAAAIASVQAADELLARTDAVVAERGRVSAELRAAGFTVPPSQANFVWLPLEDRTTDFVTQAAKAHIVVRPYGADGVRVTIAAPEENDALLRFARCWITHRDGAR
What is the function of this protein?
May catalyze the transamination reaction in phenylalanine biosynthesis.
What are the official names of this protein?
Putative phenylalanine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: UBIE_CAUSK
Sequence: MTKASATFGFKDVDASAKAGLVRGVFDRVAKNYDLMNDVMSGGVHRLWKDAVAARLNPQPGEIIIDCAGGTGDMARRFAKMTRAAQERRGGPDALINIIDYNAEMIGAGIEKGGAPEITWTVGDAQRLPLPDAYADAYVISFGIRNVTDIDAALREARRVLKPGGRFLCLEFSKPVTEALSKAYDAYSFKLIPQFGEWLAKDRDAYQYLVESIRRFPDQKTFAGMMENAGFKRVTITNFTGGVAAMHQGWAL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: CH60_HELHP
Sequence: MASKEINFSDSARNKLYEGIKQLSDAVKVTMGPKGRNVLIQKSYGAPTITKDGVSVAKEIELADPIANMGAQLVKEVASKTADAAGDGTTTATVLAYSIYKEGLRNITAGANPIEVKRGMDKASAAIIEELKKSSKKIGGKSDIAQVATISANSDENIGALIAEAMEKVGKDGVITVEEAKGINDELSVVEGMQFDRGYLSAYFVTNTDKMTAQLENAYVLLTDKKISNMKEILPLLEATMQSGKPLLIIAEDIEGEALTTLVVNKLRGVLNVSAVKAPGFGDRRKAMLQDIAILTGGQVISEELGKTLEAATLADLGSAARIVIDKDNTTIVDGKGKTKDVKDRIAQIKTEIENTTSDYDREKLQERLAKLSGGVAVIKVGAASEVEMKEKKDRVDDALSATKAAVDEGIVIGGGSALIRASQKVKLKLEGDEAIGYDIIKRAIKAPLAQIATNAGYDAGVVVNEVEKNSKDGFGFNATTGEYVDMFKEGIIDPLKVTRVALQNAVSVSSLLLTTEATINEIKEDKPAPAMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAF1_CAEEL
Sequence: MRIRHVVFCLLALVYGAETSDDDLDERTNIFIRDKLIPALKLAEVTKVNFTRLHLCHCSREVGCNARTTGWVPGIEFLNETDRSFYENTCYTDGSCYQSARPSPEISHFGCMDEKSVTDETEFHDTAAKVCTNNTKDPHATVWICCDKGNFCANETIIHLAPGPQQSSTWLILTILALLTFIVLLGIAIFLTRKSWEAKFDWYIRFKPKPGDPLRETENNVPMVTMGDGAGSSVPEVAPIEQQGSTMSTSAGNSFPPGIMPNNMKDMLDVLEETSGSGMGPTTLHKLTIGGQIRLTGRVGSGRFGNVSRGDYRGEAVAVKVFNALDEPAFHKETEIFETRMLRHPNVLRYIGSDRVDTGFVTELWLVTEYHPSGSLHDFLLENTVNIETYYNLMRSTASGLAFLHNQIGGSKESNKPAMAHRDIKSKNIMVKNDLTCAIGDLGLSLSKPEDAASDIIANENYKCGTVRYLAPEILNSTMQFTVFESYQCADVYSFSLVMWETLCRCEDGDVLPREAATVIPYIEWTDRDPQDAQMFDVVCTRRLRPTENPLWKDHPEMKHIMEIIKTCWNGNPSARFTSYICRKRMDERQQLLLDKKAKAVAQTAGVTVQDRKILGPQKPKDESPANGAPRIVQKEIDREDEQENWRETAKTPNGHISSNDDSSRPLLG
What is the function of this protein?
Probably involved in a TGF-beta pathway (PubMed:10887089).  May be a receptor for TGF-beta-like ligand daf-7 (PubMed:10887089).  Controls the decision of whether or not larvae enter a developmentally arrested state, known as dauer, in response to environmental conditions (PubMed:10887089).  Involved in regulating entry into quiescence triggered by satiety (PubMed:18316030).  Involved in sensitivity to CO2 levels (PubMed:18524955).  In AWC neurons, acts to promote expression of srsx-3, a member of the GPCR family (PubMed:20713521).
What are the official names of this protein?
Cell surface receptor daf-1, Abnormal dauer formation protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ADH2_ENTH1
Sequence: MSTQQTMTVDEHINQLVAKAQVALKEYLKPEYTQEKIDYIVKKASVAALDQHCALAAAAVEETGRGIFEDKATKNIFACEHVTHEMRHAKTVGIINVDPLYGITEIAEPVGVVCGVTPVTNPTSTAIFKSLISIKTRNPIVFSFHPSALKCSIMAAKIVRDAAISAGAPENCIQWIEFGGIEASNKLMNHPGVATILATGGNAMVKAAYSSGKPALGVGAGNVPTYIEKTCNIKQAANDVVMSKSFDNGMICASEQAAIIDKEIYDQVVEEMKTLGAYFINEEEKAKLEKFMFGVNAYSADVNNARLNPKCPGMSPQWFAEQVGIKVPEDCNIICAVCKEVGPNEPLTREKLSPVLAILKAENTQDGIDKAEAMVEFNGRGHSAAIHSNDKAVVEKYALTMKACRILHNTPSSQGGIGSIYNYIWPSFTLGCGSYGGNSVSANVTYHNLLNIKRLADRRNNLQWFRVPPKIFFEPHSIRYLAELKELSKIFIVSDRMMYKLGYVDRVMDVLKRRSNEVEIEIFIDVEPDPSIQTVQKGLAVMNTFGPDNIIAIGGGSAMDAAKIMWLLYEHPEADFFAMKQKFIDLRKRAFKFPTMGKKARLICIPTTSGTGSEVTPFAVISDHETGKKYPLADYSLTPSVAIVDPMFTMSLPKRAIADTGLDVLVHATEAYVSVMANEYTDGLAREAVKLVFENLLKSYNGDLEAREKMHNAATIAGMAFASAFLGMDHSMAHKVGAAFHLPHGRCVAVLLPHVIRYNGQKPRKLAMWPKYNFYKADQRYMELAQMVGLKCNTPAEGVEAFAKACEELMKATETITGFKQANIDEAAWMSKVPEMALLAFEDQCSPANPRVPMVKDMEKILKAAYYPIA
What is the function of this protein?
This enzyme has two NAD(+)-dependent activities: ADH and ACDH.  May be a critical enzyme in the fermentative pathway.
What are the official names of this protein?
Aldehyde-alcohol dehydrogenase 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
Protein: RNP3_METM5
Sequence: MLEGIFDINHIFDENGIKTLKRFGWDGSVAVQNHNEYSEEKINNAVEYGENCEFKVFSGLKLSTKNQNEMEKAVKKYRNKVDILLVEGGEIKINRRVLEMNDVDILSTPELNRMDNGLDHILARLGSTNRVAIELNFGNLLKSRNYDRSKILWAFQRNLKLAKKYDTPVVISSGANDIYGIKAPGDLRGFLNTITDPLYSKKIIETPSKIVDYRLYLKKDNVLTLGIEVVE
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 3, RNase P component 3, Rpp30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_SYNSC
Sequence: MTSSTPTAPTAQAHGRFIRGSVSKVRRVLDQIRGRTYRDALIMLEFMPYRSTGPITKVLRSAVANAEHNLGLDPSSLVISSATADMGPSMKRYRPRAQGRAYQIKKQTCHISIAVAAQTDS
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: NDPA_ECO45
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELHRVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGFVLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADRSTLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGGN
What are the official names of this protein?
Nucleoid-associated protein YejK.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AC4_ICMV
Sequence: MRMGSLICTCSSSSKANTNARISDSSTWYHQPGQHISIQTFRELNPAPTSSPTSTRTVILGDGEHFRSMDDQPEGVNNLQTTLTPRHLTAAVNQRLLRSLEN
What is the function of this protein?
Pathogenicity determinant (By similarity).  May act as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Protein AC4, Protein AL4.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae protein AC4/C4 family.
Protein: LPXK_ECOSE
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTSLASGN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: SOX1_MOUSE
Sequence: MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGTKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGIPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHYQGAGAGVNGTVPLTHI
What is the function of this protein?
Transcriptional activator.  May function as a switch in neuronal development.  Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
What are the official names of this protein?
Transcription factor SOX-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: YJJB_SHIFL
Sequence: MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGSIGHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISSVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: C_SENDH
Sequence: MASATLTAWIKMPSFLKKILKLRGRRQEEESRSRMLSDSSMLSCRVNQLTSEGTEAGSTTPSTLPKDQALPIEPKVRAKEKSQHRRPKIIDQVRRVESLGEQASQRQKHMLETLINKIYTGPLGEELVQTLYLRIWAMEETPESLKILQMREDIRDQVLKMKTERWLRTLIRGEKTKLKDFQKRYEEVHPYLMKEKVEQVIMEEAWSLAAHIVQE
What is the function of this protein?
The different products prevent the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways.  They inhibit IFN-alpha/beta induced tyrosine phosphorylation of STAT1 and STAT2.  Blocking the IFN-alpha/beta pathway requires binding to STAT1 in the cytoplasm.  They inhibit IFN-gamma induced serine phosphorylation of STAT1.  Block the IFN-gamma pathway by binding to and stabilizing the parallel form of the STAT1 dimer, further inducing high-molecular-weight complex formation and inhibition of transcription by IFN-gamma.  May also have a role in preventing the cell to enter apoptosis.  Modulate regulation of viral transcription and replication.  Overexpression inhibits the viral RNA polymerase.  The absence of all C', C, Y1 and Y2 proteins leads to viral delayed growth.  Plays an important role in virion particles release.  Modulates virion shape.
What are the official names of this protein?
Protein C'.
What is the protein family that this protein belongs to?
Belongs to the respirovirus protein C family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Protein C' seems to localize around the Golgi.
Protein: FHLA_SALTS
Sequence: MSYTPMSDLGQQGLFDITRTLLQQPDLASLSEALSQLVKRSALADSAGIVLWQAQSQRAQYYATRENGRPVEYEDETVLAHGPVRRILSRPDALHCNFHEFTETWPQLAASGLYPEFGHYCLLPLAAEGRIFGGCEFIRQEDRPWSEKEYDRLHTFTQIVGVVAEQIQNRVNNNVDYDLLCRERDNFRILVAITNAVLSRLDIDELVSEVAKEIHHYFNIDAISIVLRSHRKNKLNIYSTHYLDEHHPAHEQSEVDEAGTLTERVFKSKEMLLINLNERDPLAPYERMLFDTWGNQIQTLCLLPLMSGKTMLGVLKLAQCEEKVFTTANLKLLRQIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYNVLKQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRSGRRMVKMNCAAMPAGLLESDLFGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSNKLIQTDVRLIAATNRDLKKMVADREFRNDLYYRLNVFPIQLPPLRERPEDIPLLVKAFTFKIARRMGRNIDSIPAETLRTLSSMEWPGNVRELENVVERAVLLTRGNVLQLSLPDITAVTPDTSPVATESAKEGEDEYQLIIRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMKRLGIDKDALA
What is the function of this protein?
Required for induction of expression of the formate dehydrogenase H and hydrogenase-3 structural genes.
What are the official names of this protein?
Formate hydrogenlyase transcriptional activator.
Protein: MIAA_STAA9
Sequence: MNKNKPFIVVIVGPTASGKTELSIELAKRINGEIISGDSMQVYKHMNIGTAKVTPEEMDGIPHHLIDILNPDDTFSAYEFKRLAEDLITDITNRGKVPIIAGGTGLYIQSLIYNYELEDETVTPAQLSIVKQKLSALEHLDNQQLHDYLAQFDAVSAENIHPNNRQRVLRAIEYYLKTKKLLSNRKKVQQFTENYDTLLLGIEMSRKTLYSRINKRVDIMLDHGLFREVQQLVEQGYESCQSMQAIGYKELIPVINGQMIYEDAVNDLKQHSRQYAKRQMTWFKNKMSVHWLDKENMSLQMMLDEITTQIK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: IF2_WOLSU
Sequence: MQKVRVHEIALELGIKSKEIIDKAKDLDLDLKTASSALPQEEAAELVNYILTGKSSRLKPAAPAAPMPKEEEISPAPQEESQMEPKEEPQKEVKESVKEAPESLPESPKEEAFEAEIPKESVKVTPKTLEQEPPKEELVSIEPSLESASETLSDSNPLPQEKTETKETIVATTLATQTDAEIQESEEKKETLAQATVQKRVGLRIVKKRSEEPAPKADRPSLEEARTPSRTAGLKTLQSLLGESDESEAALARKKKKEKKKPLPAPTKKNEQKIDLLGDRALETVSSFDDEQEEIVLFDLTIRDDINKEDEVAKKVDTDRIKVQRKTPFLDQGIRRVKRRKRRPQTVADKESISGTIEIPEEIRAYEFAEKTGKSIGEVIKVLFNLGLMITKNDFLDRDSIEILAEELELDVVIKNTSEALEYTSEEEEDEDEEGLEERPPVVTIMGHVDHGKTSLLDKIRNTKVAAGEAGGITQHIGAYTVEKDGKKISFIDTPGHEAFTEMRARGAEVTDIVIIVIAADDGVKQQTIEALNHAKAANVPIIIALNKVDKPDANPDKVKAEAADLGYSPLEWGGEYEFVHISAKTGEGIDHLLETILVQSELLELKANPEKAAKAVVIESSLEKGKGPVATVIVQSGTLKVGDSIVADTAYGRVRALIDDCGKNIQSIGPSEVAVVTGLSETPMAGAVLVSVENDSIAREYAEKRALYLRQKELSRSTKVSFDELSAMVAEGQLKSLPVIIKADTQGSLEAIRGSLEKLRNEEVKINIIHAGVGGITESDVVLAGASDNSVILGFNVRPTGSVKNRAKELGVEVKTYSIIYALLDDVRAVLGGMMSPVLEEENTGQAEVRETFTIAKVGTIAGCLVTDGSIQRGIKVRLIRNGVVVFTGNIASLKRFKDDAREVSKGYECGIMLEGFNDVQVGDVFETYKEVEKARKL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_MANSM
Sequence: MAFKFNAEVRSAQGKGASRRLRHNGQIPAIVYGGNEDAVSIVLNHDELNNAQAHDSFYSEVITLVINGKEVAVKVQAMQRHPFKPKLVHIDFKRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: RS5_HAEIN
Sequence: MSNIEKQVGELQEKLIAVNRVSKTVKGGRIMSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNEGTLQHPVKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVRNVLSKAYGSTNPINVVRATIDALANMKSPEMVAAKRGKTVDEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SPEA_PROMM
Sequence: MSAADPIQDNKSWTVADSAALYGLDHWGHPYFSANANGHVQVQPRGDQGSCLDLVELVEELKSRNLNLPLLIRFDDILEDRLERLHSAFEEAISKYGYAGRYQGVFPVKCNQQRHVVEQLVESGRQWHFGLEAGSKAELLIALSLVNDPEALLICNGYKDQRYIETAILARRLGRQPVVVIEQPDEVERIIRSSQELGAAPFLGVRAKLTTRSTGHWSSSVGEKAKFGLSVPDLLATVEALRQADLLSDLRLLHFHIGSQINDIAVLKDALQEAAQIYVELTKLGAPMGYLDVGGGLGVDYDGSRSASAASTNYSLQNYANDVVATVRECCKPHGITLPILVSESGRAIASHFSILVFDVLGTGTVPGAIPKQTVEEPLTIHNLRETLSGVMATQKGAVSEISRLQEAWNDAIKFKEDALAAFRLGYISLPERALAEQLTGACAEAIMGQLPCNETIPDDLQSLRAVLASTYYANLSIFRSAPDTWAIEQLFPLMPIHRLNEEPTQLGHFADLTCDSDGKLDRFIGNGQTKTLLELHNLRQNEAYMIGMFLAGAYQEVMGNLHNLFGSTNAVHIRLTTAGGYQVDHVVRGNTNSEVLEAMEHNPELLLERLRLASELAIQRGELKINDVRRLMDHLEASLRQTTYLQG
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: PUN_PUNGR
Sequence: YHYYNPEENHFCATWDASKP
What are the official names of this protein?
Punein.
Protein: K15_HHV8P
Sequence: MKTLIFFWNLWLWALLVCFWCITLVCVTTNSIDTMASLLVMCILFVSAINKYTQAISSNNPKWPSSWHLGIIACIVLKLWNLSTTNSVTYACLITTAILSLVTAFLTLIKHCTACKLQLEHGILFTSTFAVLMTNMLVHMSNTWQSSWIFFPISFTLSLPFLYAFATVKTGNIKLVSSVSFICAGLVMGYPVSCCKTHTCTATAAGLSLSSIYLGFTGIISTLHKSWAPPKRGILTFLLLQGGVLTTQTLTTELLAITSTTGNIKGHEILLLVCLIFLWCLYVWQSFNKASLVTGMLHLIAAWSHTGGCVQLVMLLPSGLTRGILTMIICISTLFSTLQGLLVFYLYKEKKVVAVNSYRQRRRRIYTRDQNLHHNDNHLGNNVISPPPLPPFFRQPVRLPSHVTDRGRGSQLLNEVELQEVNRDPPNVFGYASILVSGAEESREPSPQPDQSGMSILRVDGGSAFRIDTAQAATQPTDDLYEEVLFPRN
What is the function of this protein?
Plays a crucial role for reactivation of the virus from latency, early viral gene expression and virus production.  Modulates host signaling pathways including activation of MAP kinases c-JUN-N-terminal kinase (JNK), ERK2, and NF-kappa-B resulting in the activation of AP-1 and NFAT-dependent gene expression in B-lymphocytes.  When expressed in epithelial cells, induces the expression of several inflammatory and angiogenic genes.  Interferes also with B-lymphocytes signaling through interaction with host LYN kinase.
What are the official names of this protein?
Protein K15.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network. Note=Localizes to the trans-Golgi network (TGN) compartment during latency and relocalizes to the cell periphery when the lytic program is induced.
Protein: HLGB_STAAR
Sequence: MNMNKLVKSSVATSMALLLLSNTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKAAGNINSGYERPNPKDYDFSKIYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
What is the function of this protein?
Toxin that seems to act by forming pores in the membrane of the cell.  Has a hemolytic and a leucotoxic activity.  Promotes host AMFR-mediated inflammation by mediating 'Lys-27'-linked ubiquitination of TAB3, TAK1-TAB3 complex formation and phosphorylation of TAK1/MAP3K7.  In turn, activates host NF-kappa-B signaling pathway.
What are the official names of this protein?
Gamma-hemolysin component B, H-gamma-1, H-gamma-I.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: PSBZ_HORVU
Sequence: MTIAFQLAVFALIATSSVLVISVPLVFASPDGWSNNKNVVFSGTSLWIGLVFLVAILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: PGK_LACCB
Sequence: MAKLIVSDLDVKDKKVLIRVDFNVPIKDGVIGDDNRIVAALPTIQYVIDHGGKAILLSHLGRVKTEEDKAKLTLKPVAERLSELLKKPVTFVPATRGKELEDAINKMNDGDVLVMENTRFEDLDGKKESGNDPELGKYWASLGDLFVNDAFGTAHRSHASNVGIASNMKQTAAGFLMEKEIKFLGDAVDNPKHPFIAILGGAKVSDKIGVIENLVPKADKILIGGGMTYTFYAAKGMSIGKSLVEKDKIELAKKIMDQAGDKLLLPVDSVVATEFSNDAPHKVVDGDIPDGYMALDIGPKTIKEFKDALQGAKTVVWNGPMGVFEMSNYAEGTLEVGRALGDLKDATTIIGGGDSTAAAKQLGIAPKITHISTGGGASLEYLEGKTLPGIAAISDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_ACIBS
Sequence: MSNQLPVINLMGPTASGKTALACELYERGNFELISVDSALVYKDMDIGTAKPTREEQELYPHHLIDIITPLEVYSAAQFVEDACALIDEMHSRGKTPILVGGTMLYFKALLEGLSSNLPSADANVRAAIEEKAANEGWQAVYDELVAVDPAAGVKFKVSDKQRIIRALEVYHITGQPITKLQAEQPKNVPYRYTFHNYALLPDRVELHQRIEQRLSKMWDIGFLSEVESLIEKYDLDENLPSMRSVGYRQALEFLLKSDMSLKKKQEMEDKALFATRQLAKRQYTWLRSLQEIHDFKTYLTIKQAKEDLRNSYG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.