PharMolix/UniProtQA huggingface dataset:
Protein: LAP4A_HUMAN
Sequence: MVSMSFKRNRSDRFYSTRCCGCCHVRTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVNIQYEVIGNYYSSERMADNACVLFAVSVLMFIISSMLVYGAISYQVGWLIPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQLPDFPYKDDLLALDSSCLLFIVLVFFALFIIFKAYLINCVWNCYKYINNRNVPEIAVYPAFEAPPQYVLPTYEMAVKMPEKEPPPPYLPA
What is the function of this protein?
May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.
What are the official names of this protein?
Lysosomal-associated transmembrane protein 4A, Golgi 4-transmembrane-spanning transporter MTP.
What is the protein family that this protein belongs to?
Belongs to the LAPTM4/LAPTM5 transporter family.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Note=May reside in an intracellular membrane-bound compartment.
Protein: TPIS_BUCAI
Sequence: MKKFFITANWKLNGNIKMISSFFKYLKLYSSSYLEKNTVIIAPPTIYLERVCKNISNMNIFLGSQNVDINLNGAFTGETSILMLRDIGVKYVIIGHSERRFLHHETDDIIAKKFHLIKKSNLTPILCVGETEIEKKHNQTEQVIQRQLNLILKNLGTSAFKNIIIAYEPIWAIGTGVSADPEHVQLIHVFIKNYILKYSSINRNDIIIQYGGSINHTNVKKFIEQPDINGLLIGNSSLSAKEFLEIIKIAHEHYS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF12_EUGAN
Sequence: MNLELVVQLGSLLLITVAGPLIVFFLFIRQGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS3_BURM9
Sequence: MGQKIHPTGFRLAVSRNWASRWYANNNNFAAMLQEDIGVREYLKKKLKNASVGRVVIERPAKNARITIFSSRPGVVIGKKGEDIELLKTELQRRMGVPVHVNIEEIRKPETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRLGAQGIKIMSAGRLNGIEIARTEWYREGRVPLHTLRADIDYATSEAKTTYGIIGVKVWVYKGDTLGRNDAPVVEEVTEDKRPRRNARPGDRRPRRDGEGGAPGARRGGPRRGAGKPEDGKTGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GLGB_ECOLC
Sequence: MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLTFGILYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: COAD_ACISJ
Sequence: MAHVLAVYPGTFDPITLGHEDLVRRAARLFDRVIVAVAIAHHKKTLFSLDERMEMARQALADCPQVQVESFEGLVTEFTAARGGTAMVRGLRSGTDFDYEFQLAGMNRALVPGVETVFLTPASQYQFISSTLVREIGTLGGDVAQFVSPGVHERLLHKLGRTAAA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_ECOLU
Sequence: MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ACR_MYCBO
Sequence: MATTLPVQRHPRSLFPEFSELFAAFPSFAGLRPTFDTRLMRLEDEMKEGRYEVRAELPGVDPDKDVDIMVRDGQLTIKAERTEQKDFDGRSEFAYGSFVRTVSLPVGADEDDIKATYDKGILTVSVAVSEGKPTEKHIQIRSTN
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Alpha-crystallin, Acr, 14 kDa antigen, 16 kDa antigen, HSP 16.3.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cytoplasm. Note=Associates tightly with 30S ribosome subunits (PubMed:8359926, PubMed:9766227). Probably on the external side of the cell wall (By similarity).
Protein: PDXA_HERAR
Sequence: MSKRPTIAITCGEPAGIGPEISIRAAWELRADVKSILIGDAAFLAMIAGAINPDIHLSALSWQAVRNSGLPAFPRDQITVIDCPLAAHVVPGRLDAQNGRYVLQTLDIAIDGAMQHWFDAIVTAPLQKSTINDAGVPFTGHTEYLADKTATKQVVMMLATNATLQPLRVALATTHLALKDVAAAITFDSLAGIIDILHADLQQKFGIAKPRILVTGLNPHAGEGGYLGREEIDVITPVLQAAQAKGYDVRGPYPADTLFQQKLLAGADCVLAMYHDQGLPVLKYASFGLGVNITLGLPIIRTSVDHGTALDLAAAGLGQADHGSMLEAIRVAAQMAAASKASAE
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABCCA_DICDI
Sequence: MKEIELDRPEEKKKKVKKEKKIGYGGKKSPEENSNFLSNLTFSWADGFVIHCFRNVLQLSHLWDLASYDKSEYLAKKIAKSWEIEIQKPKPSYLRAGFRAFGKLQLLSIFLYAISVGIQFVGPEILGRMVTFVVESKLGTSTEDPNMGYYYALIMFGTAMIGSFCTYHANRISFRTGDRLRSIIVLDVYKKAIKLSNSARSDTSPGQIVNLMSNDAQRMVEVFGMFNNGALALPQIIICLALLYKKIGWPTFVGLGLMLAAIPFNGMAAKKLTETRKYLVSLSDSRVKATNEILQAIKIIKLYAWEDSFAKKVIEHRNNEIKLLFSYSRYRTILIVIISALPTAAAILVISSYYGHEKSLDASRIFSALSYLNLLRLPLGFLPIIIALGIQMQIAGKRVTDFLLLPEMKDIQQIDNPSLPNGVYMKNSTTTWNKLKEDSFGLKNINFEATGTSLTMVVGSVGSGKSTLVQAMLGELEIIDGEIGIKGSIAYVPQQAWIINATLKENIIFGKELDEERYQKVLEVCALKRDIELFPQGDSVEIGERGINLSGGQKQRVSIARAVYSDADVYILDDPLSAVDSHVGKHLFHKCFKGILSSKTVILVANQLNYLPFADNTVVLKSGEIVERGTYYELINSKLEFSSILEKYGVDENVISKKDDIDEDEDEDQDTIEKVEIDLNKDEKSQPKSKSSNTDGTLISEEESEQGAVAGKVYWKYVTAGGGLLFLVSMIFFLLETGSKTFSDWWLSHWQTESSERMESILLGEEPTGLTDDQNLGIYIGLGMAAVFISVCKNFIYYEYSVYASRAIHHELFNALLKKPMYFFDQTPIGRIINRFTRDLDGIDNLIATSISTFLTLMLTVIATIILVSIIVPFLLIPLAPISIIFFFLQYFYRYTSRGLQRIEAITRSPIFNHFSETLNGVVSIRAYKKQQENILINQKRLDDNNNCYLTLQAMNRWLGLRLDFLANLITFFACIFITIDKDTISPANVGLALGYALSLTGNLNYAALQAADTETKMNSVERISQYIRGAVEAPQIIDDCRPSPDWPINGSIKFDNLVMRYREGLDPVLKGITCEIKAKEKIGIVGRTGAGKSSIVLALFRLIEASEGSISIDGENIAKFGLKDLRRNLAIIPQDPVLFSGTLRENLDPFNERSEEDLFSTIEDIQMSAVVKSLEGGLDSKVTENGENFSVGQRQLIVLARALLRKPKILVLDEATASVDGQSDSLIQATIRNKFSNCTILTIAHRLNTIMDSDRIMVLDAGKISEFDEPWTLLQNQNGLLTWLVDETGPQNAIYLRKLAEAKKNGIDINEIMPIDNETTPKDNINTPPPPPQ
What are the official names of this protein?
ABC transporter C family member 10, ABC transporter ABCC.10.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MDH_ANAMM
Sequence: MRSSRSAKVSLVGAGNIGGALAHMLGASQVVKELVLVDVAGGMTEGKVLDVGQALALLGSDVYITGGSDYAAIEHSDAVVVTAGIPRKEGMSREDLLNTNAAVVRNIAENIAKYSPGALVIVVTNPLDAMVWCMYKYSGLPANRVVGMAGVLDSARFSFFLARHMNVSVSSVSAMVLGGHGDLMLPLLRYSTVGGVPVESLIESGRLNRDDIAAIVERTRKGGEEIVKLLKTGSAYCAPAASCAHMLESYVRDKRSIMPCSAYLDGQYGVRDLFVGVPVIIGEKGVEEVVEFPLTAEEQAVFDQSVELIRGSVSAIS
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: FOLB_CHLTR
Sequence: MLLYRLDIADFRVWVSIGVSEQERHYPQPVLVSLSLFFKEEPKACSTDKVSDSVCYAELVSLIEEVATNNPCALIERLAKVLLEKIEKALAGQVSRIDLRVSKERPPIPDLLSPVSFSISREVP
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
What are the official names of this protein?
Probable dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin aldolase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: UBIA_BURTA
Sequence: MLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVVIFVLGTLLMRSAGCAINDYADRDFDRHVKRTAERPLTSGKIRAWEAVAIAVGLALVSFLLILPLNALTKELSVVAVFVAATYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPALAWMLLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRYDVLAIMLCYAAMLGIYVWVGVTQHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGALFAGIAAHYALSAL
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS2_ZYMMO
Sequence: MSEETLAYIESVIAERRKASPEDSYVSSLFHRGTAHIAQKVGEEAVETVIAALAQDKKSLESEAADLIFHLAVLLADRGSSFENVFSELRRREGVSGHAEKAARPKS
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC13_COCIM
Sequence: MAQVITNSGHDDMIHDAGMDYYGRRLATCSSDKTIKIFELEGDSHRLIETLKGHEGAVWCVAWAHPKFGTILASSSYDGKVLIWREQSSAASTGSSWSRVFDFSLHTASVNMVSWAPHELGCVLACASSDGHVSVLEFRDNSWTHQIFHAHGMGVNSVSWAPAAAPGSVISATPSTGQIRRFVTGGSDNLVKIWDYNPETKTYATSHVLEGHTGWVRDVSWSPSILSRSYIASASQDKTVRIWTSDPSNPNEWTSHQLEFDAVVWRVSWSLSGNILAVSGGDNKVSLWKENLKGQWEKVKDIEE
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: RLMG_SHESM
Sequence: MTTQFSVAGIELELFRYPASQESNLQAWDAADEHLINTLVEGGQTAVPTAIINDNFGALSCALSRLTPDWPLNVETDARTSFLGAEQNHLRNQLPMDNLTWFTSRDALPGDLALVLMKLPKNLTYFAHQLMRLSQVLPAGCKVLVGAKAKSINASLLEVFAKYLGPASASLAWKKTRVITCISDGKPRALPKEITWDIPEFNLHISNLSNVFAANKLDIGARIMLDNLPQGDFKTIVDLGCGNGVLGLRAAQLYPNANIHFIDDSEMAVASAKANWANNQLPAEKGHFHWDDCMTHLPDGVEPDLVLCNPPFHQGEAITDHIAWQMFLDARRRLKNGGILHIVGNRHLAYHVKLQRLFKNCTTVASNGKFVILQAQR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_THEKO
Sequence: MEVKVGIGDYAVAKKTGIISTYGLGSCVGITLYDRLNRVGGLLHALLPESARYGGRGNPAKYVDTGLELLIKDMMKLGASPRRLEAKLFGGAHMFTNVSNENLMVGKKNVEVAKRELKKRGIRLVAEDTGGKGGRTIYLDVSTGKVRMRKVSNGKVIEAVF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: NOP9_DEBHA
Sequence: MVQPKVRGRRAEKKSKEVNTQPEDYSPNDRSELEENDDKVESNPALKTTFFGLVDSNEIDYFKQAESTLNVNAFDNDEEREGFIRSVLEEARGKELKLVTNQICSKLMERLVLFATDRQLKNIFRQFSGHFVALAHHKYSSHVLETLLVRAAALIEKELVNDFKQDEGEVDDEISQDNDREDEAVVSMETLFVKMLDEFNPHLKTMVDHQYSSHVLRLLILIIAGKELPSTTTSNSTLRSKKSKIARKMIEIKDNDDFNRSFQTPPSFKDQLRKLCNSLGSKGDMKHMRELAINKVASPVLQLLIQVEGIVDKERTFWHLIFLSENSDKNPQEEAFVEYLLSDSVGSHFLESVIRNGGARMKYIERLYKLYMKDRVLKLSKRSTTGVFIIQALLFKLKPAEVLFILDQIIPELASLISIDENQNLELGKNIIDASISRDNYRREELIEQLFVKFAPNYDRHNPSADTSSEFLENTLHLTGSTLGNTRDDWPTAQERRRSLFLEKLMEYDHSFVVCTWLNFLALPIARFIQMCYHGVFSHVVENSLVVIPASEGEPKSVLIIRKRFLNLFQNEIVNLACNSYGSHIVDRLWNFTVLLNMYKDRIGSELASESHKVKESTYGRLVWKNWSMELFVRKKFDWKSLVKNQEEEYFGVGSHEGQNSTERVKKPIELKFEQMMKEKQMKEERAQKAEEGFNKRKNNEFEYGYDNDNKKAKIRGRNR
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: THIG_BRUO2
Sequence: MLEFYGKRFESRLLLGTAQYPSPSILADAVRASLSRIVTVSLRRESGEARAGQDFWALIKALGVAVLPNTAGCHTPREALTTAHMAREVFGTNWIKLEVIGDTDTLQPDPFGLVEAARILCDEGFEVFPYMNDDLIVAERLIEAGCKVLMPWGAPIGSGRGLNNPYALKTMRAHFPDIPLVVDAGIGVPSHAAAAMELGFDAVLINTAVAKAGDPAAMARAFALAVEAGRLAYEADPIEARDMASPSTPLLGKAFL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_ACIAD
Sequence: MISILMQTLKIATRQSPLALWQAEHIRDRLQALYPELKVELVKFVTQGDKILDTPLAKIGGKGLFVKELEAALLDGRADLAVHSMKDVPMHLPEGLSLAVICEREDPLDAFVSNHVMSFDQLPLGARVGTSSLRRKCQILKQRPDLEIIDLRGNVGTRLAKLDDGQYDAIVLASAGLKRLGLISRIRHSINAEISLPAVGQGALGLECRANDKKILDLIAPLAHQPTSACVRAERAFNAYLEGGCQVPIAGFATLTQECLTLEGRVGSVDGKTLLKDHVEGHADQAEVLGVQLAKQLLAQGAGELLRDLYQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: 13KDA_TRISC
Sequence: AGEPANNEDRFNY
What are the official names of this protein?
13 kDa protein.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.
Protein: GPM_THEAC
Sequence: MKIAILIRHGESDINVKGILSDTIDNNMLTEKGMRQAEHAAAELKGIDIKNFYSSPIKRAFDTAQIIADSFNKDVVTDQRLIEIGLGKARGRKANEFTNGLYSGHITGKIREDLEMEKWDSLQKRVVEAIASREGINVYVTHSDPIRAAISYFLEMGEEETYGLSIKNASMTVIDVEIGRILTLGAISMTDSVRKYLNIQ
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family.
Protein: LSPA_STAAN
Sequence: MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFMQVAISLLFAGALGNFIDRILTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEKEVK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCSP_ECOBW
Sequence: MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAGVLTRAEAAEINLRSDILNAVGITLDETTTRENVMQLFNVLLGDNHGLDIDTLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: MIF3_ORYSJ
Sequence: MMKRLVVLRRREPAVRFSCCGVRYGECRRNHAASTGGHAVDGCREFIAAEDGGGGNSTSAVGVAAAALKCAACGCHRSFHRRVQVYEVAWDDDCASGDTSSSSPSSSSSLSSE
What is the function of this protein?
Inhibits zinc finger homeodomain (ZHD) transcription factors, by interacting with them to prevent both their nuclear localization and their DNA-binding properties.
What are the official names of this protein?
Mini zinc finger protein 2, OsMIF2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHB8_MOUSE
Sequence: MASQLRLRSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSEDGAPRGKHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDRVIAVNLKGTFLVTQAAAQALVSSGGRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIPLGHMGDPEDVADVVAFLASEDSGYITGASVEVSGGLFM
What is the function of this protein?
Required for the solubility and assembly of the heterotetramer 3-ketoacyl-[acyl carrier protein] (ACP) reductase functional complex (KAR or KAR1) that forms part of the mitochondrial fatty acid synthase (mtFAS).  Alpha-subunit of the KAR complex, acts as scaffold protein, required for the stability of carbonyl reductase type-4 (CBR4, beta-subunit of the KAR complex) and for its 3-ketoacyl-ACP reductase activity, thereby participating in mitochondrial fatty acid biosynthesis.  Catalyzes the NAD-dependent conversion of (3R)-3-hydroxyacyl-CoA into 3-ketoacyl-CoA (3-oxoacyl-CoA) with no chain length preference, this enzymatic activity is not needed for the KAR function.  Prefers (3R)-3-hydroxyacyl-CoA over (3S)-3-hydroxyacyl-CoA and displays enzymatic activity only in the presence of NAD(+)(H).  Cooperates with enoyl-CoA hydratase 1 in mitochondria, together they constitute an alternative route to the auxiliary enzyme pathways for the breakdown of Z-PUFA (cis polyunsaturated fatty acid) enoyl-esters (By similarity).  NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol.  It efficiently catalyzes the oxidation of estradiol (E2), testosterone, and dihydrotestosterone.  Primarily an oxidative enzyme, it can switch to a reductive mode determined in the appropriate physiologic milieu and catalyze the reduction of estrone (E1) to form biologically active estradiol (E2) (PubMed:9712896).
What are the official names of this protein?
(3R)-3-hydroxyacyl-CoA dehydrogenase, 17-beta-hydroxysteroid dehydrogenase 8, 17-beta-HSD 8, 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit, KAR alpha subunit, 3-oxoacyl-[acyl-carrier-protein] reductase, Estradiol 17-beta-dehydrogenase 8, Protein Ke6, Ke-6, Testosterone 17-beta-dehydrogenase 8.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RIBA_HELHP
Sequence: MKYEISEQAKLPTRFGNFFTKSFREYGKNNTLFEHLVVFTHTLGETPLVRIHSECLTGDVFGSKKCDCGNELALAMEQIAHNTEGGMLIYLRQEGRGIGLFNKINAYALQDKGYDTVEANQQLGFAGDMRSYEIVGEIFKHFHITHINLLTNNPRKIDALAPYAKVVRHSIITPSNPHNQAYLEVKKQKLGHLL
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.