PharMolix/UniProtQA huggingface dataset:
Protein: AIM21_LACTC
Sequence: MQETQDQLEQMKTMISKPAGRKDYSLMQEESVPSTPSGSTVGSLITAVGQNEHNKVRNDEEATSSASPDGTPSTVDEGDVEESNSDISGVNEQNFENELETSLAEGKSWHSAQDLNKSHTEEPIDDPNEDKMSEINLEPSNKGIEKNATVTEKSATILAKELSATTDVKKKCLRAAKPNELPAEEYCNEDLKGAISGLERRTSKPDLETNEIQDAKSLESGIGSSGNVNEVPKQNAKHPMDSCQNLEQSAGTTSAEKEAIRALESQSSGTSQASLAKHKSETNTSIQSSTQETAQAPTVYEELGSEAERSKSHAQAYKNQTDEKEMSGEIIKENPENAIDDASSPSKEYDTPSFAGKPEEGSENLKAPAKDGEPVDSEKKKKNGGTPIEGRPLQSLEGDAPQVPQRPNKRPPPKKPSSKIAAFQAMLKQQQLMDASKTKDKQIDSGNSLLSGKRANITNNLNGIFGLPGMAPGMTPGMVPPQRPPARQQTGSDGGSQSSENQTSSQSAAPSGPQRRARGPKGRKLPAHIANVEKVETSIKTNEIQVLKTWSLKFQKISPTCSEKDSEPLKDIPESGVVSPSNPKSMSELNGVPVESDVICERETDILQNSKNEMNDLEDTNEDNVKEPRQFSIPTHFDLGESDANQEESS
What is the function of this protein?
Involved in mitochondrial migration along actin filaments.
What are the official names of this protein?
Altered inheritance of mitochondria protein 21.
What is the protein family that this protein belongs to?
Belongs to the AIM21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Cortical actin patches.
Protein: CIA30_CAEEL
Sequence: MITSFPVRNFLPRVTITSCAFFSKESTSAAGTVAEKKESELQKFAGKSNLLEKKKVGIFGTSTVPINTNFPNPKGVVDYDPDFSIKELVAELPNTRKTQGAKLSEEIKNAFNSVSIEKTELLEDIGFVRHNEARVDYRFDTQEKLDLWKIGCDSDWKEGFSTCSLVNSDRGTAVFSGNISTKVLKDGRVERAGWASMKLEDRKAFNRKKFLSKWRNFSHLLLKVRGDGRSYKIMLHSPLSMDFTWGDSFSHPLHTHGGPYWQYEKIPFSKFFHTVAGRIQDRQYRVNLEDTSSIGIVLMDRIDGDFRLEIDYIGVYNDTTHVEDFAYETYTLPVFNTHGF
What is the function of this protein?
Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).  Required for normal growth and reproduction.
What are the official names of this protein?
Probable complex I intermediate-associated protein 30, mitochondrial, NADH ubiquinone oxidoreductase assembly factor 1.
What is the protein family that this protein belongs to?
Belongs to the CIA30 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SURE_HAES1
Sequence: MHILLSNDDGIQAEGIKTLAKELRKFAQVTVVAPDRNRSAASSSLTLVEPLRPMKLDNGDYSINGTPADCVHLALNGFLSGQIDLVVSGINAGVNLGDDVIYSGTVAAALEGRHLSLPAIAVSLDGRQHYESAAIIVSQLIPKLYGRLLKSREIININVPDLPYSEIKGIKVCHLGYRAAAADIIKQKDPRGEEIYWIGPIGLAENESEGTDFHAVKNGYVSITPIQTDMTAYHSMTALQQWLDKE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIME_ONCMY
Sequence: MNRTTSRQTTSSSSYKRMFGGEGRPSVGMARSTLSSRQYSSPVRSSRMSYSVSAPPSIYASKNVRLRSSAPMPRLSSDTVDFALSDAINSEFKANRTNEKAEMQHLNDRFASYIDKVRFLEQQNKILLAELEQLKGKGASRIGDLYEDEMRDLRRQVDQLTNEKAHVEVDRDNMGEDIERLREKLQDEMIQKEEAEHNLQSFRQDVDNASLARLDLERKVESLQEEIIFLRKLHDEEVAELQAQIQDQHVQIDMDVAKPDLTAALRDVRVQYETLASRNLQDSEDWYKSKFADLSEAANRNTDAIRQAKQEANEYRRQVQALTCEVDSLKGTNESMERQMRELEESFGCEANNFQDTISRLEDDIRNMKDEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRITTPMPNFSSFNLRESMLEARPMIDNLSKKVVIKTIETRDGHVINESTQNHDDLE
What is the function of this protein?
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.  Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
What are the official names of this protein?
Vimentin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix.
Protein: YHAA_BACSU
Sequence: MSISTLQKEINKQLDGCFEEMVEIRRHFHMYPELSFQEEKTAAFIASYYESLGVPIRTNVGGRGVLANIEGSEPGPTVALRADFDALPIQDEKDVPYASKVPGVMHACGHDGHTAALLAVAKVLHQNRHELKGTFVMIHQHAEEYYPGGAKPMIDDGCLENTDVIFGTHLWATEPLGTILCRPGAVMAAADRFTIKVFGKGGHGAHPHDTKDAVLIGSQIVSSLQHIVSRKVNPIQSAVISTGSFIADNPFNVIADQAVLIGTARSFDENVRDILEKEIEAVVKGICSMHGASYEYTYEQGYPAVVNHPAETNHLVSTAKNTEGVQQVIDGEPQMGGEDFAYYLQNVKGTFFFTGAAPEQPERVYSHHHPKFDINEKAMLTAAKVLAGAAITYHQL
What are the official names of this protein?
Putative amidohydrolase YhaA.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: RPOC2_PROMS
Sequence: MTSSKPKKTSRVRKTTKNSKKNNPVTMPALAKTPPSFKNKVVDKKALKNLVSWAYKTHGTAITAAMADNLKDLGFKYATQAAVSISVDDLKVPDAKQDLIGQAEEQISATEECYRLGEITEVERHTKVIDTWTETNERLVDAVKNNFNQNDPLNSVWMMANSGARGNMSQVRQLVGMRGLMANPQGEIIDLPIRTNFREGLTVTEYVISSYGARKGLVDTALRTADSGYLTRRLVDVAQDVIVREEDCGTERSIVVEAEDGKFGARLLGRLTAEDVLDAEENLLVPQNTAIDPALSGEIEKASINKVKIRSPLTCEANRSVCRRCYGWALAHNHLVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVSTAESGVVRSKISGKVEFSSKAKIRGYRTPHGVEAKQAEVDFILKIVPQGNNSGKAQKIEVSSGSLLFVDDGEEINSDITVAQITAGAVKKSVEKATKDVICDLAGQVRYDKVIQPKEVTDRQGNITLKAQRLGRLWVLAGDVYNLPPNARPVISSGKSVDEGTVLAEASQSSEFGGQVRLRESIGDSREVQIVTTSMSLTNFKLIEESTHSGQIYNLESIDGISYRLNISPGSKISNGEVIADLTDERFRTKTGGLVKYAPGLSVKKARSSKNGFEVSQGGTLLWIPQETHEINKDISLLMIEDMKWIEAGTEVVKDIFSQTSGIVTVTQKNDILREITIRNGTFHECDDEEVLNRFTEEGNLVNPGEKILDGVDNKEILFVQKLETPKCRGLLLRTVEEFTIPDQAELPQLAHVKQEKGPYLGLKAIQRLTYKDGELIKSVEGVELLRTHLSIESFDATPQMTIDVESIEDKNDSSINRLNLVILESILVRRDTISDSSHGSTHTELQVNDNQLVKAGDVISTTQILCKEKGLVQLPNVVDDEPIRRLIVERQEDKIKIKISDKALVKVGDRVVDGDPISKSIKSTFCGEIEEVSNSSVTLRYGRPYMVSPDSVLHVKDGDLVLRGDGLALLVFERQKTGDIVQGLPRIEELLEARRPRDAAILCKKSGIVQIKQGNDEESVSLSVIEKDDLVNEYQLLVGKNLMVSDGQQVAGGEPLTDGPLNPHELLDCYFNDLKDQKPLLDAARESISKLQRSMVSEVQNVYKSQGVAIDDKHIEVIVRQMTSKVRIEDAGDTTLLPGELIELRQVEDTNQAMAITGGAPAEFTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFSGFVEELSSEAGPHPDILAEESGGYRRAQNLRPDYTVDMPQSPAVSSSAILDDPSDEDLETTRNRHGIDPSSSNFAAFARPNAENQFSEDQLPDPAALEGLQEEGLLSDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: RL27_MARSD
Sequence: MAHKKAGGSSKNGRDSNAQRRGVKRFGGQEVLAGNILVRQVGSKVHAGKNVGTGKDWTLFALVDGVVKYEKYIRKNRVKTRVHIVPAEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GLFT2_MYCS2
Sequence: MSDIPSGALEADESRAVSLLSRVILPRPGEPLDVRKLYIEESTTNSRRAHAPTRTSLEIGPESEVSFATYFNAFPASYWRRWSTLDTVVLRVELTGTARVDVYRSKATGARITVGGAPVAGEGDGPAAVEFEIDLTPFEDGGWIWFDITTNTAVRVHSAGWYAPVPAPGRANVAVGIPTFNRPADCVNALAALTSDPLVDEVISAVIVSDQGTSKAKDHPGFADAAARLGDRLSIHNQPNLGGSGGYSRVMYEALKNTDCEQILFMDDDIRIEPDSILRALAMNRFAKSPILVGGQMLNLQEPSHLHVMGEVVDRANFMWTAAPNAEYDHDFAKFKLSDAEEPRTKLLHRRVDVDFNGWWMCMIPRQIAEELGQPLPLFIKWDDAEYGLRAGEHGYGTVTLPGAAIWHMAWSDKDDAIDWQAYFHLRNRLVVAALHWDGPVSGLIASHLKATIKHLLCLEYSTVAIQNKAMEDFLAGPENLFSILESAMPDVRKLRSQYPDAVVLPGATSLPPASDMRRKKIAIPVSKPAIAVNLARGVVHQLRSHDPETHVRPQINVATQDARWFSLCRVDGVTVTTADGRGVVYRQRDRAKMFALLRASLRQQARLARKFDRMRKVYRDALPMLTSTQKWESVLLTETPEKVGR
What is the function of this protein?
Involved in the galactan polymerization of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacteria cell wall.  Thus, successively transfers approximately 28 galactofuranosyl (Galf) residues from UDP-galactofuranose (UDP-Galf) onto the galactofuranosyl-galactofuranosyl-rhamnosyl-GlcNAc-diphospho-decaprenol (Galf-Galf-Rha-GlcNAc-PP-C50) acceptor produced by GlfT1, with alternating 1->5 and 1->6 links, forming a galactan domain with approximately 30 galactofuranosyl residues.
What are the official names of this protein?
Galactofuranosyltransferase GlfT2, GalTr 2, Arabinogalactan galactosyltransferase 2, Galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase, Polymerizing galactofuranosyltransferase GlfT2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: 5DNU_SHISS
Sequence: MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVNMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAKTRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_PSEA8
Sequence: MDIKGALNRIVNQLDLTTEEMQAVMRQIMTGQCTDAQIGAFLMGMRMKSETIDEIVGAVAVMRELADGVQLPTLKHVVDVVGTGGDGANIFNVSSAASFVVAAAGGKVAKHGNRAVSGKSGSADLLEAAGIYLELTSEQVARCIDTVGVGFMFAQVHHKAMKYAAGPRRELGLRTLFNMLGPLTNPAGVRHQVVGVFTQELCKPLAEVLKRLGSEHVLVVHSRDGLDEFSLAAATHIAELKDGEVREYEVRPEDFGIKSQTLMGLEVDSPQASLELIRDALGRRKTEAGQKAAELIVMNAGPALYAADLATSLHEGIQLAHDALHTGLAREKMDELVAFTAVYREENAQ
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: MDTK_ECOSM
Sequence: MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRAAR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UD19_HUMAN
Sequence: MACTGWTSPLPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMRSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQVRSIYSLLMGSYNDIFDLFFSNCRSLFKDKKLVEYLKESSFDAVFLDPFDNCGLIVAKYFSLPSVVFARGILCHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHRFFKNALEIASEILQTPVTEYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
What is the function of this protein?
Lacks UGT glucuronidation activity but acts as a negative regulator of isoform 1.
What are the official names of this protein?
UDP-glucuronosyltransferase 1A9, UGT1A9, UDP-glucuronosyltransferase 1-9, UDPGT 1-9, UGT1*9, UGT1-09, UGT1.9, UDP-glucuronosyltransferase 1-I, UGT-1I, UGT1I, lugP4.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: ATG8B_ARATH
Sequence: MEKNSFKLSNPLEMRMAESTRIRAKYPERVPVIVEKAGQSDVPDIDKKKYLVPADLTIGQFVYVVRKRIKLGAEKAIFVFVKNTLPPTAALMSAIYEEHKDEDGFLYMTYSGENTFGGSFYC
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.
What are the official names of this protein?
Autophagy-related protein 8b, Autophagy-related ubiquitin-like modifier ATG8b, AtAPG8b, Protein autophagy 8b.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor. Cytoplasm, cytoskeleton.
Protein: TRPD_PROM2
Sequence: MFSNLSNSEILNNLLEGRDLDDLTSRSLMQRWLNDKVSDVETGAFLSALRAKGSTGVELSSMAEELLNVCDLPVARPNLYLVDTCGTGGDGANTFNISTAVAFVAASCGVKIAKHGNKSASGKVGSADVLLNLGLNLNCSLEKVINAVNEIGITFLFAPVWHKSLIKLAPLRKTLGIRTVFNQLGPLVNPLRPNAQVLGVASEDFLKPMGSALLKMGMNRAIVVHGSGGLDEASLQGENKLVFVENGELRFSEINISDFNHENIANEKLVVSDFQSNDEILKSVLNGSGQKSHIDVVALNAALVLWVAGIEDDLNEGFNKALISINQGDPWKKFLLLKNYLSEN
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: IF2A_MOUSE
Sequence: MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEVDGDDDAEEMEAKAED
What is the function of this protein?
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (PubMed:15277680, PubMed:19131336).  This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex (PubMed:15277680, PubMed:19131336).  Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex (PubMed:15277680, PubMed:19131336).  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B (PubMed:15277680, PubMed:19131336).  EIF2S1/eIF-2-alpha is a key component of the integrated stress response (ISR), required for adaptation to various stress: phosphorylation by metabolic-stress sensing protein kinases (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2) in response to stress converts EIF2S1/eIF-2-alpha in a global protein synthesis inhibitor, leading to a attenuation of cap-dependent translation, while concomitantly initiating the preferential translation of ISR-specific mRNAs, such as the transcriptional activators ATF4 and QRICH1, and hence allowing ATF4- and QRICH1-mediated reprogramming (PubMed:15277680, PubMed:21285359).
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
What are the subcellular locations of this protein?
Cytoplasm, Stress granule. Note=Colocalizes with NANOS3 in the stress granules.
Protein: PHMT_MYCBP
Sequence: MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWAYEEDPPMDLPLEASDEPNRAHINLYHRTATQVDLGGKQVLEVSCGHGGGASYLTRTLHPASYTGLDLNQAGIKLCKKRHRLPGLDFVRGDAENLPFDDESFDVVLNVEASHCYPHFRRFLAEVVRVLRPGGYFPYADLRPNNEIAAWEADLAATPLRQLSQRQINAEVLRGIGNNSQKSRDLVDRHLPAFLRFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD
What is the function of this protein?
Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL).
What are the official names of this protein?
Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase family.
Protein: UFM1_XENTR
Sequence: MSKVTFKITLTSDPRLPYKVLCVPENTPFTAVLKFAAEEFKVPAATSAIITNDGIGLNPAQTAGNVFLKHGSELRLIPRDRVGSC
What is the function of this protein?
Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer.  The so-called ufmylation, requires the ufm1-activating E1 enzyme uba5, the ufm1-conjugating E2 enzyme ufc1, and the ufm1-ligase E3 enzyme ufl1.  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.
What are the official names of this protein?
Ubiquitin-fold modifier 1.
What is the protein family that this protein belongs to?
Belongs to the UFM1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RDR2_ORYSJ
Sequence: MPTAAAAATASLRVSNIPPSAVAAELLAFFDSAVAVAGGAFACEIAAAHRGWLSRGHGTVQFGSAAAAAAAAGLASSGRLPRFLGALLSVSPSPVDLLPRASDLSLRAAGAGLVVGDRVAERVFEAADAWDGVRAEVIPGKRRVDLYLEHDSQRYKLEVLFEDMKDCLGCTLDGMGAILLQLNYAPRIHTAISGPAVNSRFMDDRFHACKEDAKFSWVRALDFTPNYSFGRCSTLVLKLGKSALVSDILKSLPFSGNLGELTMNSMDGVGASSNVVPLVHCPRDYSVPYEVLFRLNSLMHMGKIVAKHVNADLFKALQELPVDVSRRIFEKMHKLESTCYGPLQFIQQEAYSMKRSHNVLLSNEGEGEGERKLMKCYRVNITPSKIFCFGPEEEVTNYVVKHHSAYASDFVRVTFVDEDWSKLSSNAISARIEQGFFSKPFKTGLYYRILSILKKGFSIGPKNFEFLAFSASQLRGNSVWMFASNASLNAGGIRRWMGHFENIRSVSKCAARMGQLFSSSRQTFEVLRWDVEVIPDIEITTDGSKYIFSDGIGKISLRFAKRVAHHVGLDPTNLPSAFQIRYGGYKGVIAIDPMSSIDLSLRPSMKKFESESRMLNITSWSKSQPCYVNREIISLLSTLGIRDEIFVAMQQDEMRETEEMLTNKEVALSVLGKLGGSETKTAVKMLLQGYEPSSEPYLSMILKAHQENRLTDIRTRCKIHVPKGRVLIGCLDETGVLEYGQVYIRITKNSKEQKDSNQSYFYNDDGKTATVVGKVAITKNPCLHPGDIRVLEAIYDPDLVGMVDCLVFPQRGERPHPNECSGGDLDGDLYFITWDDKLIPEKVDTPMDYTATRPRIMDHVVTLEEIQKHFVDYMINDSLGAISTAHLIHADRSPLKARSPECLQLATLHSMAVDFAKTGAPAEMPRTLRPREYPDFMERWEKPMYISNGVLGKLYRSAMGHMEKSGDSGALSSSSAQPSPTYDPDLEVPGSDEFLQAAEEYYELYEEKLTTLMNYYRAELEDEILTGNIRNKMLYLKRDNKRYFEMKDRIVAAVDALHREARGWLLSSRKEEDASRMASAWYRVTYHPDRRRGKRFWSFPWIACDNLLAIKASSQLRRRRQKDDDSTAVVQMDCSA
What is the function of this protein?
Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).
What are the official names of this protein?
Probable RNA-dependent RNA polymerase 2, OsRDR2.
What is the protein family that this protein belongs to?
Belongs to the RdRP family.
Protein: NSP2_ROTHP
Sequence: MAELACFCYPHLENDSYKFIPFNSLAIKCMLTAKVDKKDQDKFYNSIVYGIAPPPQFKKRYNTNDNSRGMNYETPMFNKVAILICEALNSIKVTQSDVANVLSRVVSVRHLENLVLRKENHQDVLFHSKELLLKAVLIAIGQSKEIETTATAEGGEIVFQNAAFTMWKLTYLDHKLMPILDQNFIEYKITLNEDKPISDICVKELVAELRWQYNRFAVITHGKGHYRVVKYSSVANHADRVFATYKNNAKSGNVTDFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKKLLFQKMKQEKNPFKGLSTDRKMDEVSHVGI
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: DAPAL_PYRAE
Sequence: MKLEGVIVATVMPFAKDGVNYEGLRLLLSKIVEAGYHGVFPTSSTGEVTKLSAEERVRVMQLAKEVAGGKALVVAGTGTGDHVSTIDIARKYKDVGVDAILITPPYYIQYDWAALYAFYKKVLDKVDIPVILYTIPLATGYNVPVEVFEMVAGEYSQVVGVKDSSGDFRYHLDLIHLLGKRLSVLQGLDMLFVPSLVMGAHGGILAGPNFLGRITLEQYLLVKEGKIAEAVALHNKLMPLWRFMGGCGLVGKLGGKWPTLYKLATQLVHGIDMGPPREPLPPVDDKDRRELEKILKELGLI
What are the official names of this protein?
Uncharacterized DapA-like lyase PAE2915.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6E_METAR
Sequence: MADFKLVVSDPKTGKAYNVDVTGPRVNKFIGKPIGSEIDGETAGLPGYKLIITGGSDKDGIPMRGDIPGQVRRRVLVSGGIGYHPTENGMRRRKLLRGDEISAEIVQVNATVAAYGEKPLDELAPKKEKKEGAAGGRAPAKK
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: FXRD1_XENLA
Sequence: MYVSSLKFPFLGIGVWKGVRLWRQRSLGTSACALKQDDFIKELDQNFVRLQKKLMDSLPSSDWSPFTPTGDLPPERADVVIVGGGVMGWSIAYWLKQKENRRGALKVVVVERDPTYSRASTVLSAGGIRQQFSRPENIQMSLFSAQFLRNINEHLGVVNEDRIDIQFNPSGYLFLASEEGATIMEENYNVQRECGAQVTLMLPDQLKKKFPWINTNGVALASYGLENEGWFDPWTLLNAFRRKALSMGVYQCHGEVTDFSTAKREMITADGDPVTFSRIGHVTVQMPNSLESQSVECSLVINAAGAWSSKVAELAGIGTGPSNSLEGIKLPVEPKKRYVYVVHCPNGPGLDCPLLIDNSGAYFRREGLGGNYIAGKSPAEEEEPDISNMEVDHDFFQEKVWPLLAHRVPAFESLKVKTSWAGYYDYNTYDQNGVVGMHPLVNNLFFATGFSGHGLQHSPAVGRAVAELIVDGGFKTLNLSSFSFRRFWSQEPLLERNIV
What is the function of this protein?
Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I).  Involved in mid-late stages of complex I assembly.
What are the official names of this protein?
FAD-dependent oxidoreductase domain-containing protein 1.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: KPYK_EMENI
Sequence: MAASSSLDHLSNRMKLEWHSKLNTEMVPAKNFRRTSIICTIGPKTNSVEKINALRRAGLNVVRMNFSHGSYEYHQSVIDHAREAEKQQAGRPVAIALDTKGPEIRTGNTVGDKDIPIKAGHEMNISTDEQYATASDDQNMYVDYKNITKVISAGKLIYVDDGILSFEVLEVVDDKTLRVRCLNNGNISSRKGVNLPGTDVDLPALSEKDISDLKFGVKNKVDMVFASFIRRGSDIRHIREVLGEEGREIQIIAKIENQQGVNNFDEILEETDGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGNYPCEAVTMMSETCLLAEVAIPHFNVFDELRNLAPRPTDTVESIAMAAVSASLELNAGAIVVLTTSGNTARMISKYRPVCPIIMVSRNPAATRYSHLYRGVWPFYFPEKKPDFNVKIWQEDVDRRLKWGINHGLKLGIINKGDNIVCVQGWRGGMGHTNTVRVVPAEENLGLSE
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: NDKB_MERBI
Sequence: MEQTFIAIKPDGVQRGLCGEVMKFIQPMKHYLDLKDMPFYAGLCKYMSSGPVFAMVWEGEGIVKMMLGETNPADSKPGSIRGDFCINIGRNIIHGSDTVENAKMEVGLWFKPEEFVAYAEKAKAWVYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.
What are the official names of this protein?
Nucleoside diphosphate kinase B, NDK B, NDP kinase B.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, lamellipodium. Cell projection, ruffle.