PharMolix/UniProtQA huggingface dataset:
Protein: COAE_FRACC
Sequence: MFTVGLTGGIGSGKSAVSACLAARGALLIDADQVARDVVAPGTPGLAAVLAEFGTELANADGGLDREALGRIVFADPAARGRLEAIVHPLIREETARRMGEVSPSGIAVHDIPLLVEVHAEGTYDVVLVVEAPRELRLHRLEGRGLPRDQALARMANQATDSQRRAAADIVVDNGGSLDDLDARIEEVWQDLLARRDAKATAKATAKAETVASGTDTAASGTDTAAPAG
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCS_BRADU
Sequence: MILWRIVRPGAAMAYVQTGLVLIAEAMDTQQDSLKPRPAMRAAAFSVHVFTAFGAAIALLAMLEAVREHWAAMFQWLGVALIIDAIDGPIARRLDVKNVQPNWSGDVLDLVVDFVTYVFVPAYAIVASGLLLPVAAPLLGVAIIVTSALYFADLRMKADDNHFRGFPALWNAAAFYLFLLHWPPLWSTLLVAALVVLTFVPFHVLHPVRVVRLRWLTMSLIGIWAVLSLYTLDMDFRVGPGVTLALCAIALWISFSDALIRFARSFA
What is the function of this protein?
Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
What are the official names of this protein?
Phosphatidylcholine synthase, PC synthase, PCS, CDP-diglyceride-choline O-phosphatidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SOXR_SALTY
Sequence: MEKKSPRLKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSGNQRRYKRDVLRYVAIIKIAQRIGIPLATIGDAFGILPEGHTLSAKEWKQLSSQWREELDRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEHGTGARLLEDD
What is the function of this protein?
Activates the transcription of the soxS gene which itself controls the superoxide response regulon.  SoxR contains a 2Fe-2S iron-sulfur cluster that may act as a redox sensor system that recognizes superoxide.  The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity).
What are the official names of this protein?
Redox-sensitive transcriptional activator SoxR.
Protein: RTL9_HUMAN
Sequence: MSIPLHSLRFNNTMREENVEPQNKQMAFCRPMTETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGMLTPALCYLLEEQEAARGSCSVEEEMEIDEEKQMKGFLDDSERMAFLVSLHLGAAERWFILQMEVGEPLSHENKSFLRRSQGIYDSLSEIDILSAVLCHPKQGQKSVRQYATDFLLLARHLSWSDAILRTRFLEGLSEAVTTKMGRIFLKVAGSLKELIDRSLYTECQLAEEKDSPGNSSQVLPTACKRNNEEAMGNELSSQQQTEEHQHVSKRCYYLKEHGDPQEGLHDHLGQSTGHHQKAHTNK
What are the official names of this protein?
Retrotransposon Gag-like protein 9, Retrotransposon gag domain-containing protein 1, Tumor antigen BJ-HCC-23.
Protein: GLPK_SALNS
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIVSVSQREFEQIYPKPGWVEHDPMEIWASQSSTLVEVLAKADISSDQIAAIGITNQRETAIVWERETGKPIYNAIVWQCRRTADICEQLKRDGLEDYIRDNTGLVVDPYFSGTKVKWILDHVEGSRERAKRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHDLDWDDKMLDVLDIPRAMLPQVRKSSEVYGQTNIGGKGGTRIPIAGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPSGEVNYALEGAVFMAGASIQWLRDEMKLISDAFDSEYFATKVKDTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNSNHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGYWQNLDELQEKAVIEREFRPGIETTERNYRYSGWKKAVKRAMAWEEHDK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RS21_RHOP5
Sequence: MQVLVRDNNVDQALKALKKKMQREGIFREMKLRGHYEKPSEKKAREKAEAVRRARKLARKKLQREGLLPMKPKPVFGAGPGGDRRGPGAGPGAGPRPAR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: LOR1_ARATH
Sequence: MQQPYEYRYPQGTGPSAPPPPPKAGVIVDPKYCSLHPVDLAIVRKVLKITDGNFVITNAEGNLLFKVKDPFFSLHEKRILMDGFGTKVLTLKGKIMTMHDRWLVFRGGSTEEVDLLYTVKRSNMVQITTKLDVFLADNIEQKKCDYRLEGVWLETSCFVYAGDSDIILAQMREKKTMQSVLFGKDNFCLTVNPNVDYAFIASLIVILVEIQISLRKLTKQLLLE
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 1.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: LEPA_PROMH
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLTDREMAAQVLDSMDLERERGITIKAQSVTLNYTADDGEVYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIDMDLTVVPVLNKIDLPAAEPERVAEEIEDIVGIDATDAVRCSAKTGVGVKEVIERLVKEIPAPEGDPDAPLQALIIDSWFDNYLGVVSLIRIKNGKVNKGDKIKVMSTGQVYNIDRIGIFTPKQVDTTSLSCGEVGWVVCGIKDILGAPVGDTLTAAQKPADKPLPGFKKVKPQVYAGLFPVSSDDYESFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVEMTNGDIIMVDSPSKLPALNNIEEIREPIAECHMLLPQEYLGNVITLCVEKRGVQTNMVYHGNQVSLTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFLRFQGSNMVRVDVLINGERVDALALITHNDNAPYRGRELVEKMKEFIPRQQFDIAIQAAIGNHIIARSTVKQLRKNVLAKCYGGDVSRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y271_SYNY3
Sequence: MRINHKPLLIATALLTLVPNVVWSSPFDEDQEICPQWECDQAGNCRKLDLTCGSSPDSSGAQGYQLYFDGELVSGPDAQGYTSQQAKENCTWNMQTKPQMHIRCLYNGQVFGDRPPSNSPGYELYFDGELVSGADAQGYTFQQAEENCIWNMQTKPQIHIRCLYNGQVFRER
What are the official names of this protein?
Uncharacterized protein slr0271.
Protein: CYF_TRIEI
Sequence: MSKINLSTMWSSFIKKIAKTILVAIACISLFLTSSPAANAYPFWAQETAPATPREATGRIVCANCHLGAKLTEVEVPQSVLPDTVFKAVVKIPYDTDVQQVLGDGSKGGLNVGAVLMLPEGFKIAPEDRIPQEWQEELADLYFMPYSEEQENVLLFGPMPGDEYQEVVFPILSPDPATDKSIHFGKYAVHAGGNRGRGQVYPAGNKSNNTTYNVSASGKITDITFEEYVGNQITIETPDSETVVDLVPPGPELLVAVGDTVEAGQVITNNPNVGGFGQADTEIVLQDANRVKWLMAFFALVMLAQIMLVLKKKQVEKVQAAEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: GATC_CAMJE
Sequence: MQIDEKLLSKLEKLSALQITKNRNETIAQLSEIVNFVEKLNELDLDSQEITVSTIKGGAPLRIDEIRNSNVIDEVLDCAPKKQEHFFVVPKIIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: TTLL7_HUMAN
Sequence: MPSLPQEGVIQGPSPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYTFVPRTWIFPAEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQKAEAQRRLYGQNSIKRLLPGSSDWEQQRHQLERRKEELKERLAQVRKQISREEHENRHMGNYRRIYPPEDKALLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKTRGPKPLCSMPESTEIMKRPKYCSSDSSYDSSSSSSESDENEKEEYQNKKREKQVTYNLKPSNHYKLIQQPSSIRRSVSCPRSISAQSPSSGDTRPFSAQQMISVSRPTSASRSHSLNRASSYMRHLPHSNDACSTNSQVSESLRQLKTKEQEDDLTSQTLFVLKDMKIRFPGKSDAESELLIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVLDIVKTSIRTVLPRIWKVPDVEEVNLYRIFNRVFNRLLWSRGQGLWNCFCDSGSSWESIFNKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYATDKRGSLSGIGPDWGNSRYLLPGSTQFFLRTPTYNLKYNSPGMTRSNVLFTSRYGHL
What is the function of this protein?
Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin (PubMed:16901895, PubMed:25959773).  Mediates both ATP-dependent initiation and elongation steps of the polyglutamylation reaction (PubMed:16901895, PubMed:25959773).  Preferentially modifies the beta-tubulin tail over an alpha-tail (PubMed:16901895, PubMed:25959773).  Competes with monoglycylase TTLL3 for modification site on beta-tubulin substrate, thereby creating an anticorrelation between glycylation and glutamylation reactions (By similarity).  Required for neurite growth; responsible for the strong increase in tubulin polyglutamylation during postnatal neuronal maturation (By similarity).
What are the official names of this protein?
Tubulin polyglutamylase TTLL7, Testis development protein NYD-SP30, Tubulin--tyrosine ligase-like protein 7.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, dendrite. Perikaryon. Note=In cells with primary cilia, found in both cilia and basal bodies. In neuronal cells, found in dendrites and perikaryon.
Protein: TRPA_GEOKA
Sequence: MPLSVNPPLFIPFIVAGDPAPDVTIDLALALEEAGADILELGVPYSDPLADGPTIQRAAARALDGGMTLPKAIQLIGEMRKKGVNIPIILFTYYNPVLQLGEESFFALARENGADGVLIPDLPFEESGPLRELGERFGLPLISLVAPTSKQRIERIASAAQGFLYCVSSLGVTGVRETLPETLGDFLREVKRHSRVPVAVGFGISAPEQVAMLKEVCDGVVVGSALVQKVEQLAPRLQTPDEREAAVAEFAAYARSLAAPLREAYSSR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: Y1093_YERPS
Sequence: MKTKLNELLEFPCSFTYKVMGIAEPQLVDQVVEVVQRHAPGEYTPQVKPSSKGNYHSVSITITATHIDQVETLYEELGNLELVKMVL
What are the official names of this protein?
UPF0250 protein YPTB1093.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: CAN2_MOUSE
Sequence: MAGIAIKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGYKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPPDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGERGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELTGQTNIHLGKNFFLTTRARERSDTFINLREVLNRFKLPPGEYVLVPSTFEPHKDGDFCIRVFSEKKADYQAVDDEIEANIEEIDANEEDIDDGFRRLFVQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIQLNLASWLSFSVL
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.  Proteolytically cleaves MYOC at 'Arg-226' (By similarity).  Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (PubMed:22711986).
What are the official names of this protein?
Calpain-2 catalytic subunit, 80 kDa M-calpain subunit, CALP80, Calcium-activated neutral proteinase 2, CANP 2, Calpain M-type, Calpain-2 large subunit, Millimolar-calpain, M-calpain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Protein: FBPAP_METJA
Sequence: MSRMENNKVTISVIKADVGGLCGHTLAPDELLEACEAVLEEAVDEIILDYYVTRCGDDIDLIMSHKLGCDNEKVHGLAWRAFEEATKVAKELKLYGAGQDLLADSFSGNVRGMGPGCAEMEFVERKSEPIVVFCCDKTDPTAFNYPLFKMFADPFNTAGLVFDPSMISGFKFEVHDVVGHKKVFLDTPEEMYMLLALIGDYEKYAIKRVYRRRDNEIAAVVSTEKLNYIAGEYVGKDDPVAIVRAQSGFPAVGEVLEPFANPHFVPGWMRGSHWGPLMPVGEEDATPTRFDGPARIIALGFQVCDGMLIGPNDLFADKGFDKAREKALEMADIIRRMGPFQPHRLPATMMEYTTVPKVLEALEDRFIPLEGLELIEEGGITRKDRGDVE
What is the function of this protein?
Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
What are the official names of this protein?
Fructose-1,6-bisphosphate aldolase/phosphatase, FBP A/P, FBP aldolase/phosphatase.
What is the protein family that this protein belongs to?
Belongs to the FBP aldolase/phosphatase family.
Protein: PSBX_PROMT
Sequence: MAFHLLNLFLSAGTSSEAATSSAVGMIGSFLAAGALIVAPAAAALIWVSQKDALSR
What is the function of this protein?
Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.
What are the official names of this protein?
Photosystem II reaction center X protein.
What is the protein family that this protein belongs to?
Belongs to the PsbX family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ACHA_NATTE
Sequence: ADGIFAIDQFTKVLLNYTGHITWNPPAIFKSYCEIIVTYFPFDEQNCSMKLGTRTYDGTVVAIYPEGPRPDLSNYMQSGEWALKDYRGFWHSVNYSCCLDTPYLDITYHFILLRLPLYFIVNVIIPC
What is the function of this protein?
Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity).  Does not bind alpha-bungarotoxin.
What are the official names of this protein?
Acetylcholine receptor subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-1/CHRNA1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: CCM2L_MOUSE
Sequence: MEYEAKKGKKGFVSPIRRLVFPKAARQAAFRSSVSRRPLHSMPLYPPDYLIDPHILLCDYLEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTPEQDSILSLSARCLLLTWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGMDGSPGGSGRDPGPPGAAPEKRRVGTAERRHTICSLDWRVAWGGGAGAEARAAGGGGSLERQRAGARASGSWERRQTFSGSWERRHAGGGAGKPGGSWERRQASGGVGGSWERRHPGPNPLDPQNHSPDAYCNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYRSTPKRPWLSSCTMAPRTHLKRATVAHPHRLSTAPTAAVSTTAAGPSSSYRITWSRCGVSWVLLRSSSLHCCYETIVWGCLSRTTVQVCRNSMGTDGSSFSLECGPSSQIRTSATSRASWRVWVSARAESSLTALAASSAA
What are the official names of this protein?
Cerebral cavernous malformations 2 protein-like, CCM2-like.
What is the protein family that this protein belongs to?
Belongs to the CCM2 family.
Protein: INT7_DANRE
Sequence: MSLSAARSFLSEAAYGEQELDANSALMELDKGLRSCKLGEQCEAVVLFPKLFQKYPFPILINSAFLKLADIFRLGNNFLRLCVLKVTQLSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAIFAAASFSSHSKDFAAGICNKISEMIQGLDTPVELKLKLIPMLQHMHHDASLASCSRELLQELVSSYPSTSMLIVTLHTFTQLATSSLVDIPEQICLLLQYLKEDPRKAVKRLSIQDLKLLAKKAPHLWTRKNIQVLCECALHTPYNSLKLGMLSVLSTLSGTIAIKQYFSPNAGDSSPAPHHTDLVKLAQECCYHSDLAVAAHGITVLTSIAAFCPEKEVIQLEQETVMGMESLILLCSQDDSKTAQATLKTALTSLVQMLKTCPHLSQSSVELLLRQLHCACDPARVLMCQALAAIATQQPVLVEGMLGDLLELFRVASHRTSEKQQELLVSLATVLFVASQASLSAEVKAVIRQQLENVANGWTVYQIARQASRMGCHDFSRELYQSLRTRVASEHFYFWLNSLMEFSQAEQCLSGLEDGDYSAAMSAISEALKSYQKGIASLTAASTPLSPLTFQCEFVKLRIDTLQALSQLICTCNSLKTSPPPAIATTIALSSGSDLQRCGRISTQMKFSMDEFRSLAARYADLYQSSFDADYATLRNVELQQQSCLLVSYVIEALIIDPQTASFQEFGTHGSILAESEYELRMMAVFNHVLEEVENLSRKHPPVSYLHTGCLCDTVIAILKIPLSFQRYFFQKLQSTSIKLALSPSPRTPNEPIPVQNNQQLTLKVEGVIQHGSSPGLFRKIQAVCLKVSSTLQTKPGSDFKIPLESKTNEIEQKVEPHNDYFSTQFLLNFSILGTHQVSVEASVVDTSGIEWKTGPKNTVSVKSLEDPYSQQLRHQLQQQQQNVPQPAAQRNISTRFQ
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  May play a role in DNA damage response (DDR) signaling during the S phase (By similarity).  Essential during embryogenesis for eye development.
What are the official names of this protein?
Integrator complex subunit 7, Int7.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 7 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: IPAJ_SHIFL
Sequence: MSEQRKPCKRGCIHTGVMLYGVLLQGAIPREYMISHQTDVRVNENRVNEQGCFLARKQMYDNSCGAASLLCAAKELGVDKIPQYKGSMSEMTRKSSLDLDNRCERDLYLITSGNYNPRIHKDNIADAGYSMPDKIVMATRLLGLNAYVVEESNIFSQVISFIYPDARDLLIGMGCNIVHQRDVLSSNQRVLEAVAVSFIGVPVGLHWVLCRPDGSYMDPAVGENYSCFSTMELGARRSNSNFIGYTKIGISIVITNEAL
What is the function of this protein?
Virulence factor that eliminates N-myristoyl protein modifications in infected host cells.  Acts as a cysteine protease that cleaves the peptide bond between N-myristoylated Gly-2 and Asn-3 of human ARF1, leading to the elimination of the myristoyl group and alteration of protein trafficking in host cell.  Could also cleave an array of N-myristoylated host proteins involved in cellular growth, signal transduction, autophagasome maturation and organelle function.
What are the official names of this protein?
Cysteine protease IpaJ, Effector protein IpaJ, Invasion plasmid antigen J.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cytoplasm.
Protein: TEX33_MOUSE
Sequence: MELSHRQGTTTLTRTHPNDKEGQQDMNSFRANHSSLDNSKFKYHARLSQSPLGSSLGQGYLETPPLPPTPTCRTSLAMNSHPEDLKKGASRSSSRDARETFREGCVGEEGQDSRSPEQRTVPLSKKDSVIPENIRHKFGSKMVDQLISEDQARQAIGEMFEGQKRPSSWPSRTQSPMQASSIFSDYYDLGYHMRSNLFQGPPQETKSLMKASYTPEVIEKSVRDVEHWHGRKTDDLGRWHRKNAMNMNLQKALEEKYGEKSRSKAK
What are the official names of this protein?
Testis-expressed protein 33.
Protein: RL17_ACIC5
Sequence: MRHRNAGYKLGRNTSHRRALLRNLVTSILMEDRVETTITKAKAARPHVEKLITLGKKGDVHSRRQALAYLQTREAVTRLFDTVAPRYGDRNGGYLRIVRSGFQRGDGAEKAFIELLGAEQELDEKRQKRAEARAKRREEMQKAMAEQQQAEGGEPEGGNE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RNH2_STRA5
Sequence: MATIKEIKAILETIVDLKDKRWQEYQTDSRAGVQKAILQRKKNIQSDLDEEARLEQMLVYEKKLYIEHINLIAGIDEVGRGPLAGPVVAAAVILPPNCKIKHLNDSKKIPKKKHQEIYQNILDQALAVGIGIQDSQCIDDINIYEATKHAMIDAVSHLSVAPEHLLIDAMVLDLSIPQTKIIKGDANSLSIAAASIVAKVTRDKIMSDYDSTYPGYAFSKNAGYGTKEHLEGLQKYGITPIHRKSFEPIKSML
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB_BACTN
Sequence: MSVNKVILIGNVGQDPRVKYFDTGSAVATFPLATTDRGYTLANGTQIPERTEWHNIVASNRLAEIVDKYVHKGDKLYLEGKIRTRSYSDQSGAMRYITEIFVDNMEMLSPKGANTGAGAPQPSATQAQQPQQMQQPQQPQQQAQPSQAQPIQDNPADDLPF
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: RS18_NITEU
Sequence: MANRPLFKRKKFCRFTAEGIKHIDYKDIDLLKDFVSENGRIIPARITGTRAYYQRQLNLAIERARFLALLPYTDQH
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: EFG_STRZT
Sequence: MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAHPIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAVAETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLQSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEKSKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVISGMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTARRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQEEIIKKNKGED
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK10_DICDI
Sequence: MRSVLSFEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQDKDGIPLTSLREIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNINKPFKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGCQKYSTAVDLWSIGSIFGELLIGRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRLNNIPHQPYNNLRELVPTISDTAFDLLNQLLTYDPTKRITASDAIKHPFFYENPFPQSIEMMPKFPTISKSFKNQNKKQNNNFNNFVQNNQTNQNNQTNQNNQTNQNNKTSQNNNMDSYKYSK
What are the official names of this protein?
Probable cyclin-dependent kinase 10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: RS7_ICTPU
Sequence: MFSSSAKIVKANGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGSRKAIIIFVPVPQLKAFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVYPSEIVGKRIRVKLDSSRLIKVHLDKAQQNNVEHKVETFAGVYKKLTGKDVVFEFPEFQL
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for rRNA maturation.
What are the official names of this protein?
40S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS7 family.