PharMolix/UniProtQA huggingface dataset:
Protein: RS18_COXBU
Sequence: MSFRRKKFCAFDAKNLQEIDYKDVNTLKDYIMESGRVVPSRITGTCAKHQRQISRAIKLARYLALLPYCDTHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SG196_HUMAN
Sequence: MEKQPQNSRRGLAPREVPPAVGLLLIMALMNTLLYLCLDHFFIAPRQSTVDPTHCPYGHFRIGQMKNCSPWLSCEELRTEVRQLKRVGEGAVKRVFLSEWKEHKVALSQLTSLEMKDDFLHGLQMLKSLQGTHVVTLLGYCEDDNTMLTEYHPLGSLSNLEETLNLSKYQNVNTWQHRLELAMDYVSIINYLHHSPVGTRVMCDSNDLPKTLSQYLLTSNFSILANDLDALPLVNHSSGMLVKCGHRELHGDFVAPEQLWPYGEDVPFHDDLMPSYDEKIDIWKIPDISSFLLGHIEGSDMVRFHLFDIHKACKSQTPSERPTAQDVLETYQKVLDTLRDAMMSQAREML
What is the function of this protein?
Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose).  Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.  Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.
What are the official names of this protein?
Protein O-mannose kinase, POMK, Protein kinase-like protein SgK196, Sugen kinase 196.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: AGR3_MOUSE
Sequence: MLHSALALCLLLITVSSNLAIAIKKEKRPPQTLSRGWGDDITWVQTYEEGLFHARKSNKPLMVIHHLEDCQYCQALKKEFAKNEEIQEMAQNDFIMLNLMHETTDKNLSPDGQYVPRIMFVDPSLTVRADITGRYSNRLYTYEPQDLPMLVDNMKKALRLIQSEL
What is the function of this protein?
Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway.  Might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
What are the official names of this protein?
Anterior gradient protein 3.
What is the protein family that this protein belongs to?
Belongs to the AGR family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Cytoplasm.
Protein: RL6_ACIAD
Sequence: MSRVAKAPVTVPNGVAVTQNGRQVEVKGTKGTLSFNLHALVELKQEEGKLQLAPVKESKDAWMQAGTARAVLNNLVKGVSEGFERKLQLIGVGYKAAVKGTSINLNLGFSHPIDYSLPEGVTAETPTATEIILKSADKQLLGQVASEIRGYRPPEPYKGKGVRYSDEVVLRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SSRP_STRP4
Sequence: MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARINLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTGMTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: DAPE_KLEP3
Sequence: MSCPVIELAQQLIRRPSLSPDDAGCQALMIERLRAIGFTVEPMDFGDTQNFWAWRGHGETLAFAGHTDVVPAGDADRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQYPNHRGRLAFLITSDEEASAKNGTVKVVETLMARNERLDYCLVGEPSSTEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPMLAELVNIEWDKGNEFFPPTSMQIANVQSGTGSNNVIPGDMFVQFNFRFSTELTDEMIKARVVSLLEKYQLRYSVEWWLSGQPFLTGRGKLVDAVVSAIEHYNEIKPQLLTNGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRVMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RS10_SHESA
Sequence: MQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTVLISPHVNKDARDQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ELP5_HUMAN
Sequence: MTPSEGARAGTGRELEMLDSLLALGGLVLLRDSVEWEGRSLLKALVKKSALCGEQVHILGCEVSEEEFREGFDSDINNRLVYHDFFRDPLNWSKTEEAFPGGPLGALRAMCKRTDPVPVTIALDSLSWLLLRLPCTTLCQVLHAVSHQDSCPGDSSSVGKVSVLGLLHEELHGPGPVGALSSLAQTEVTLGGTMGQASAHILCRRPRQRPTDQTQWFSILPDFSLDLQEGPSVESQPYSDPHIPPVDPTTHLTFNLHLSKKEREARDSLILPFQFSSEKQQALLRPRPGQATSHIFYEPDAYDDLDQEDPDDDLDI
What is the function of this protein?
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:29332244).  The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244).  Involved in cell migration (By similarity).
What are the official names of this protein?
Elongator complex protein 5, Dermal papilla-derived protein 6, S-phase 2 protein.
What is the protein family that this protein belongs to?
Belongs to the ELP5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NRFA_WOLSU
Sequence: MTKFKLLLAGSLVAIVSMGLLASNINEREKERVALNKTAHSQGIEGKAMSEEWARYYPRQFDSWKKTKESDNITDMLKEKPALVVAWAGYPFSKDYNAPRGHYYALQDNINTLRTGAPVDGKTGPLPSACWTCKSPDVPRIIEQDGELEYFTGKWAKYGDEIVNTIGCYNCHDDKSAELKSKVPYLDRGLSAAGFKTFAESTHQEKRSLVCAQCHVEYYFKKTEWKDDKGVDKTAMVVTLPWSKGISTEQMEAYYDEINFADWTHGISKTPMLKAQHPDWELYKTGIHGQKGVSCADCHMPYTQEGAVKYSDHKVGNPLDNMDKSCMNCHRESEQKLKDIVKQKFERKEFLQDIAFDNIGKAHLETGKAMELGATDAELKEIRTHIRHAQWRADMAIAGHGSFFHAPEEVLRLLASGNEEAQKARIKLVKVLAKYGAIDYVAPDFETKEKAQKLAKVDMEAFIAEKLKFKQTLEQEWKKQAIAKGRLNPESLKGVDEKSSYYDKTKK
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.  Has very low activity toward hydroxylamine, and even lower activity toward sulfite.  Sulfite reductase activity is maximal at neutral pH.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MYB30_ORYSJ
Sequence: MGRAPCCEKMGLKRGPWTAEEDRILVAHIERHGHSNWRALPRQAGLLRCGKSCRLRWINYLRPDIKRGNFTREEEDAIIHLHDLLGNRWSAIAARLPGRTDNEIKNVWHTHLKKRLEPKPSSGREAAAPKRKATKKAAAVAVAIDVPTTVPVSPEQSLSTTTTSAATTEEYSYSMASSADHNTTDSFTSEEEFQIDDSFWSETLAMTVDSTDSGMEMSGGDPLGAGGASPSSSNDDDMDDFWLKLFIQAGGMQNLPQI
What is the function of this protein?
Acts as negative regulator of cold tolerance.  Negatively regulates beta-amylase genes at the transcriptional level in response to cold stress.  Suppresses beta-amylase gene expression by interacting with TIFY11A/JAZ9.  Maltose produced by beta-amylases has a role in protecting cell membranes under cold stress conditions in rice and may contribute to the cold tolerance as a compatible solute.
What are the official names of this protein?
Transcription factor MYB30, OsMYB30.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS21_STAAB
Sequence: MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: SSRP_RHIEC
Sequence: MAPKGSQRVVNKVVAENRKARFNYEIIDTYEAGLVLKGTEVKSLREGKANIAESYASDEDGEIWLINSYLPEYLQANRFNHEPRRRRKLLLSGREIHRLRSAVNREGMTLVPLKIYFNDRGRAKMELALAKGKKLHDKRESEKERDWNRQKSRLLKDNG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: AAE8_ARATH
Sequence: MEDLKPSAANSLPLTLLGFLERAATVYGDCTSIVYGNSTVYTWRETNHRCLCVASALSSIGIGRSDVVSVLSANTPEMYELQFSVPMSGAILNNINTRLDARTVSVLLRHCESKLLFVDFFYSDLAVEAITMLLNPPILVLIANEEEEEGGAEVTERSKFCYLYSDLITRGNPDFKWIRPGSEWDPIVVNYTSGTTSSPKGVVHCHRGIFVMTLDSLTDWAVPKTPVYLWTLPIFHANGWTYPWGIAAVGGTNVCVRKLHAPSIYHLIRDHGVTHMYGAPIVLQILSASQESDQPLKSPVNFLTAGSSPPATVLLRAESLGFIVSHGYGLTETAGVIVSCAWKPNWNRLPASDQAQLKSRQGVRTVGFSEIDVVDPESGRSVERDGETVGEIVLRGSSIMLGYLKNPIGTQNSFKNGWFFTGDLGVIHGDGYLEIKDRSKDVIISGGENVSSVEVEAVLYTNPAVNEAAVVARPDEFWGETPCAFVSLKPGLTRKPTDKEIIEYCKYKMPRYMAPKTVSFLEELPKTSTGKIIKSLLKEIAKNM
What is the function of this protein?
May act as an acid--thiol ligase that activates carboxylic acids by forming acyl-CoAs.
What are the official names of this protein?
Probable acyl-activating enzyme 8, AMP-binding protein 8, AtAMPBP8.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: CHD1L_DANRE
Sequence: MSTFLRAVRDNIPEKDKSELTENDLKKWGLGAIHLRPYQLDGVKWLSLCMKNQQGCILGDEMGLGKTCQTISLLAYARGSLKMNGPFLVLCPLAVLENWRQELERFCPSLSVICYTGDKEKRAELQQNLKSDPRFHVLLTTYEMCLKDARYLKSWKWKILVVDEAHRLKNQESLLHQTLKEFTVGFRVLLTGTPIQNNLQEVYSLLTFIQPSVFLPEAVEDFVNAYADIQTEPALVDELHQVLQPFLLRRVKAEVAAELPKKTELVVFHGLSALQKRYYKAILMRDLDAFRTDQSTKTRLLNVLMQLRKCVDHPYLFDGVEPEPFEMGEHLVEASGKLSLLDSMLAYLQEGGHHVLLFSQMTRMLDILQDYLEYRGYSYERLDGSVRGEERNLAIKNFSTKDVFIFLLSTKAGGVGMNLTAADTVIFVDGDFNPQNDLQAAARAHRIGQTRPVKVIRLLGRDTIEEIIYSRAVSKLRLTDTVIEEGRFSLLDQAQSAASGLQLSEILKFGVDKLLSSEESSVQDVDLQLILGQSRDGQWLTDEEHAKLNESNEEEDEDMEGQNHMYYFEGKDYSKDPSAEDEKTFELLLEKQFAEMEDAEKEGRALRNKAGVSLSGPLINPARKKRPLTEAELEERRQKRQAAAAKRAKLQEERKKQQEELNYKKKMAWWDSCGYRSLCLPRVDSEGEDMEPDEDDHVSFSSTDSDHTAIRYVLGDVTHPQADREDAIIVHCVDDSGHWGRGGLFTALGLRSDEPRKQYELAGDMKDLELGNVLLFPVDDKQSRLCGRDYLALIVAQQRDKANKLSGIRLTALDEGLKKIYKAAKQKKASVHLPRIGHSTKGFNWYGTERLIRKHLATRGIFTSIYYYRRGSSHATVSSTASTTTPSSSKPAASSPSESPHSSSPPANREGLTKSAELSTTSHEGPGAPGLADFMRGVHVYFYNMAATEKKKLTRYLITYDGDEEDLMSSHVTHIVGEVESPVHKQELQDLLHQYPQALLVKKNWLESCFASQRKVSVSKYVIRLT
What is the function of this protein?
ATP-dependent chromatin remodeler that mediates chromatin-remodeling following DNA damage.  Recruited to DNA damage sites through interaction with poly-ADP-ribose: specifically recognizes and binds histones that are poly-ADP-ribosylated on serine residues in response to DNA damage.  Poly-ADP-ribose-binding activates the ATP-dependent chromatin remodeler activity, thereby regulating chromatin during DNA repair.  Catalyzes nucleosome sliding away from DNA breaks in an ATP-dependent manner.
What are the official names of this protein?
Chromodomain-helicase-DNA-binding protein 1-like.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage.
Protein: TIG_DEIGD
Sequence: MAELISKEGNKVSFRVAVPAAEVNRAYDQVWAGLARDVRVPGFRPGKAPRKVLESRVGKGYVENEVRDRLLQVHYPQAARELKLSLVDARIEPEPLVSGQPFSFTVRGETYPEVTLGDWRAVQLTATAPEITDEVLNRTLSDLQERNATFQTVERPIEATDQVTIEELGEEGGSYPVYLDVAEPHVRDALIGKNVGDEVEITVPAHQHGDHEHPEHTVRVRVQSVQTKQLQPLDDEFARSLNFESLDRLRTDLRAELERRARQEGDAARREEFVNQLVEGMQVEIPQALIDRRREAMLEEIQDDLGRQGVKWSEYENFMREQGKLDEFLSDLAKNAESRVKRDLALEKLAEDLGVQLSDAEFSNTMNALAQANGLTPQQLQRQLGPNGINAYYISLTREKALQQALATLNGQQVAGRQEAGAEQTAQAAEQESGQPQAEGEQAAEQRGE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: F16P2_ORYSI
Sequence: MDHEADAYRTDLMTITRYVLNEQSRNPEARGDLTILLSHIVLGCKFVASAVNKAGLAKLIGLAGETNVQGEEQKKLDVLSNEVFVKALVSSGRTCVLVSEEDEEATFVDPALRGKYCVCFDPLDGSSNIDCGVSIGTIFGIYMIKDKENVTLEDVLQPGKNMVAAGYCMYGSSCTLVLSTGNGVNGFTLDPSLGEFILTHPDIKIPKKGKIYSVNEGNAKNWDEPTAKFVEKCKFPKDGSSPKSLRYIGSMVADVHRTLLYGGVFLYPADKKSPNGKLRVLYEVFPMSFLMEQAGGQSFTGKERALDLVPTKIHERSPIFLGSFEDVEEIKGLYAAQAK
What are the official names of this protein?
Fructose-1,6-bisphosphatase, cytosolic, FBPase, D-fructose-1,6-bisphosphate 1-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHG05_MOUSE
Sequence: MMAKNKEPRPPSYTVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYISTLPRAFNTLLPDLEEIEHLNWLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQYCTDIKVENLLATSLLEMDHNRVRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYILSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMTNLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPTGTYPRKFNESQIKQALRGVLESVKHNLDVVSPVPINKDVSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPVHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDSSDNYVEPLDTIFKQKGYSDEIYVVPDDSQNRIIKIRNSFVNNTQGDEENGFSDRTSKGHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQEVDDKKIKKKTHKVKEDKKQKKKTKTFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERFHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAPPPTSNPGQLVESMVPLQLPPPLQPQLIQPQLQTDPLGII
What is the function of this protein?
GTPase-activating protein for Rho family members.
What are the official names of this protein?
Rho GTPase-activating protein 5, Rho-type GTPase-activating protein 5, p190-B.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also membrane-associated in a fibrillar pattern that colocalizes with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin.
Protein: Y4400_RICRS
Sequence: MAGHSKFKNIQHRKGAQDKKRAKVFTKLIREIVTAAKTGSSNNPENNPRLRNALTAARSQNLPKERIDKALNSANESSNNENYTEIRYEGYAPNGIAIIVEALTDNKNRTAAEVRSSFTKYGGSLGETGSVNYLFNHCGVIQYPINIASNEDVLEAVIEAGGHDIISDDTTHTIYTDVENFSKVLDFFTGKYGIPEDSYIGWIPLNTIIIDDKEKAAKLLKLVEVLEESDDVQRVFGNYELSDDVYEIIQGEP
What are the official names of this protein?
Probable transcriptional regulatory protein A1G_04400.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF3_BRAJU
Sequence: MPRSRINGNFIDKTFTIVADILLRVIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIQQGDSEMAEAWFAQAAEYWKQAITLTPGNYIEAQNWLTITRRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PDXS_SALAI
Sequence: MPESQSPNSSTNAPVTGTTHVKRGMAEMLKGGVIMDVVTPEQARIAEDAGAVAVMALERVPADIRAQGGVSRMSDPDMIDGIMQAVSIPVMAKARIGHFVEAQILQSLGVDYVDESEVLTPADYANHVDKWAFTVPFVCGATNLGEALRRITEGAAMIRSKGEAGTGDVSNATTHMRGIRTEIRRLQSLPADELYVAAKELQAPYELVREIAETGKLPVVLFTAGGIATPADAAMMMQLGAEGVFVGSGIFKSGNPAERAAAIVKATTFHDDPEVLAKVSRGLGEAMVGINVDQIPQSDRLAERGR
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: METE_SALRD
Sequence: MATASNLGYPRIGAHRELKRAVEGYWKGDLTKDELRDSAQALRESHWATQQELGLDVVPSNDFSYYDQVLDACAMVGAVPERFPWDGTEVDLDTYFAMARGLQEKDLEGEESGVQAMEMTKWFDTNYHYIVPEFSHDTTFSLSSTKVIDEYEEAKAQGVDTRPVVIGPVSFLLLGKTQADDLDALDLLDDLLPVYAEVLQELADAGCEAVQLDEPNLVLDLSDAERAALDQAYEALADAADIELHVATYFGGLEDNLPTALDLPIDVLHLDLTRGEEQLDEALDHGVPDDLALSLGVIDGRNVWRADLDALLGTVETAIDALGTDRVLVGPSCSLLHVPVDLDTEPGLSDEMKTWFAFATQKIEEIVALAERADGHEDATEALFEKSRRAHAARAESDWINDAAVQDRVAGIDASMTERDSPHSSRSPLQREALDLPTLPTTTIGSFPQTDDMRRMRAQYKKDEISKDEYEDFIEEQIADTIAAQEEIGLDVLVHGEPERGDMVEHFGRQLDGFLFTENGWVQSYGTRCVRPPIIAGDVSRPEPMTTRWLSYANDQTDTPVKGMLTGPVTMLQWSFVRDDQSRAETCRQIALAIRDEVLDLEDVGIQAIQIDEPAFREGLPLREHQWDDYLDWAVECFRLASSGVRDETQIHTHMCYSEFNDIIEAIADMDADVISVEASRSKMELLDSFDAFDYPNEIGPGVYDIHSPRVPSVEEMEELIRTALDALEPSQMWVNPDCGLKTRRWVEVQPSLENMVQAAENVRERATA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: Y6453_DICDI
Sequence: MTIKIRSEETCTESKFFYHNQDVTYNYHLDMVDNGINIWTSIHGKNAGLLPFVFQSFQISSEEDAISFYKYVKLIGTGCYVAILISGNLPYHSKRITKAMKLVGGGSKSIETLSDSNPNFCLIGYKGQKIGSARQAIGDADIEEEGGISVWMMTTKNRCLFKNRILINLRNKTPLGTISQLYKKHIKKEMTNNIYL
What are the official names of this protein?
Putative uncharacterized transmembrane protein DDB_G0285347.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y296_STRPD
Sequence: MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAIREMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK
What are the official names of this protein?
UPF0154 protein MGAS10270_Spy0296.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: UROK_MOUSE
Sequence: MKVWLASLFLCALVVKNSEGGSVLGAPDESNCGCQNGGVCVSYKYFSRIRRCSCPRKFQGEHCEIDASKTCYHGNGDSYRGKANTDTKGRPCLAWNAPAVLQKPYNAHRPDAISLGLGKHNYCRNPDNQKRPWCYVQIGLRQFVQECMVHDCSLSKKPSSSVDQQGFQCGQKALRPRFKIVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVVYLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQTICLPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLDWIQSHIGEEKGLAF
What is the function of this protein?
Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
What are the official names of this protein?
Urokinase-type plasminogen activator, U-plasminogen activator, uPA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: H35_STYLE
Sequence: NTGAKAPRKQLANKAARKSTNVNAVSGVKKPHRFRPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQEYKSDLRFQSQAVLALQEAAEAYLVGLFEDTNLCAIHAKRVTIMP
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3-5.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TRPD_METS4
Sequence: MDSFKPYLAKVATGAALTREEARTAFDHLLSGEVTHAQAGAFLMALRVRGEAQDEIVGAAGALRERMVRVVAPAGAIDIVGTGGDHSGSYNVSTLASILTAACGVPVAKHGNRAASSRSGAADVLAALGVRLGLDPEGLARCLEEAGLCFMFAQAHHASMRHVAPVRVELGTRTLFNLLGPLCNPAGVAGQLLGVYAGSLAEPLTRVLADLGSRRVWTVHGSDGLDEITTTGPTAVVALEDGAIRHFTIDPREVGLALASPEDLRGADPEHNAAALRAVLDGARTPYRDIAVLNAGAALVVAGACAGLGEGVARAAQAIETGAARAVLARLVAVSNA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.