PharMolix/UniProtQA huggingface dataset:
Protein: POPI_SCHPO
Sequence: MKRSTGGTQPKGLNVKRSKLADARFIEVESPALSNGAVDLKKFIESRSFEITALQDAMKRSKESSAQRAFQALPRCLRRRAASHNIKRIPKGLRDRALYEMQLSSSSTLPIAPSRQRLKRFIKRLRRKLAKSGETKAIDSTGSLVTDNSTDDSRIPSLAAVKLIRGKFAGRQLRKVWLPTHLWVCKRAHMINAWGYAIPEKPTEKSYRPTHRAAFRKDAIAFDMSYEPLFCISGPYEALKEKFGNSFANGLPPVFLNSSRSFTSYLVKSDIHELICPCFLQWNNPTEDDKKQIPVKNPTECVQLVIRLHPSAFLQAWNYLSGIAVLDDRIAMHDWRLDLASFDIHGPDSNIMLHKVFDDVELDEAGKVWQSISNYSSACLPMGASISVKALVNTRCDKNLSEKGEKSLLDSAENSLPASANQYSTHFRYWERQEIPSFAVFENKNRHTHEKKSSEKEVIPVYITYRKEWNGLTVILPWDYAKFVWRKMMYQKGIRFGGLENLHQIAFEKRMPFFPIDYPDTISGQLCEEERKKRNEDSWKRRPPAKRVNYQKFGDNFSEIGNPFCCDWVYLNEMVKASRDEDKTLQLVRVQVQLVQRGSLQDRARIYCLSDDELSKWKTIIYKENLTAENLLYPKCPNETAIIGFVTTGNFNLNAGKPSGIANVLAKTIKNEKSGYCIIRNVGCSVPRLAQWKFNQSH
What is the function of this protein?
Required for processing of 5. 8S rRNA (short form) at site A3 and for 5' and 3' processing of pre-tRNA.
What are the official names of this protein?
Ribonucleases P/MRP protein subunit pop1.
What is the protein family that this protein belongs to?
Belongs to the POP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DCAM_HORCH
Sequence: MAAPVSAIGFEGYEKRLEITFSEASIFADPHGRGLRALSRAQIDSVLDLARCTIVSELSNKDFDSYVLSESSLFIYSQKIVIKTCGTTMLLLTIPRILELAEELCMPLAAVKYSRGMFIFPGAQPAPHRSFSEEVDVLNRYFGHLNSGGNAYVIGDPAKPGQKWHIYYATEQPEQPMVTLEMCMTGLDKTKASVFFKTHADGHVSCAKEMTKLSGISDIIPEMEVCDFDFEPCGYSMNAINGSAFSTIHVTPEDGFSYASYEVQGMDASALAYGDIVKRVLRCFGPSEFSVAVTIFGGRGHAATWGKKLDAEAYDCNNVVEQELPCGGVLIYQSFAANEELAVSAGSPRSVFHCFENVESGHPLVKEGKLANLLAWRAEEESLEEGTGALLCE
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: SYFB_PSYA2
Sequence: MKISEQWLRQWVNPNNSSEQLADQLTMAGLEIDDRFAVARAFSGVVVGEVISVEQHPDADKLRVTQVNIGAVEPLQIVCGAPNVTVGMKVPVATVGAVLPSDDGTGFKIKNGNLRGVDSNGMLCGASEIDLTDNIDGLLELPTDAPIGTDIREYLGLDNQILDISITPNRGDCFSVRGIAREISVINDLPLQMPNIPDNNQVIHNEAMPAVTVSAVEACPRYFLQSISNIDRTIDTPKWMQDALVQSGLRSHNFLVDVTNYVLMELGQPLHAFDADTIVGDIVVRLAQPEETITLLNEQTISLTGDELVIADDKGALALAGIMGGQRSSVTDSTTNIVLESAFFNPLAIAARARRFGLHTDASQRFERGVDFELPALALARAVDLITSVTGSQAGQIVAMENSDHLPARAPITLPITKVRDVIGIEIEPVVMVRILTQLGFKVEQQADSLICTPPSYRFDMSIKEDLIEEIARIYGYDNIPSILPHLQVSMDYDDTADLTHEMKLALVDNGYMEAISFSFSDAKLEALLDDKALGEVLALANPISSDLAVMRRTLLSSLLPCVQYNLNRQQSRVRFFETGLSFVGHSVSDLVQTPSIAIVAVGDVWDEQAYQNRALDFYDLKHDIEQLLPAKIDNARIRYERSQLAFLHPGQSAKLYIDDQYVGWLGQLHPNTAKQLDLTTTWVAQLSLAPLLTLAREQHAITTPSKFPQVRRDIAILVDSDISLQTLESTIRKASGTLLTDLWLFDVYQGEKVPAGQRSLAFALIWQDKTQTLSDDAVKTATDKVVQALTVEHSAQLRDS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_BORRA
Sequence: MKVILREDFINLGKEGDIVDVKDGFARNYLLPKGFAVFSNKHNIDIFSQKKRAILKRQESRRKMAVELKEKLDKVNLEFIMQSNDSGKLFHSINSSNIADELLKLGFEIERRKIDMHHGALKAFGTYNVIIKLYEGISSVITVEIKREEKKNSLKKSKSVKKEV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: BUR1_KLULA
Sequence: MSTVNKKPASLKYKIGKVKQIPTVVKDDKTGLEYIQVQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETGLDLLSKLLALDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPPSAPTGHTSTDNSIRAVTGAAFPKEASIPKAPRPEHIKSTIPAQPSASRYNGAATQNIPKEPIPTAPLPKGPKNSIPTGPNKLPPNPRDSYASKYPAESRFGVNTRITTESYNAGKRYRNRGGWETGRDSLNYNNNYAPPADRSHHPTIQRPSAPRGGSYPNRYQNQDYNTSRNTGYNQYSQAGDRRSYRPGASENPGTIGHGSSQSTQKDSKSSHSNNVKPKDVADYY
What is the function of this protein?
Serine/threonine-protein kinase involved in transcription regulation.  Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes.  Also required for histone H3 methylation.  Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase BUR1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURQ_RHOBA
Sequence: MLNQLNQLTTEASNPASAQIDSLSALQIVQLINQQDALVAAAVNTQAEMIAEAVDVIADRFRSNGRLIYLGAGTSGRLGVLDASECPPTFRTPPEMVVGVIAGGPEALTRAIEGAEDHPEFAERDLAKINLSSNDVLVGIATSGRTPYVIGGLKYARSIGAFTIGLSCNPNCQLRPLSQIMIAPIVGPEIVSGSTRMKAGTATKMVLNMLTTGAMIRIGKTYGNRMVDVRATNEKLVARSRQMLSEIVGISGDQAEQLLQQCDGEVKTAIVVHIKEVSPQTARQMLVDVDGHLSRLLATPSE
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: NDK_LISW6
Sequence: MEQTYVMVKPDGVERGLIGEIVAKIEKKGIKLVAGKLIQIDRKLAEQHYAEHIGKPFFEDLIGFITSGPVFAMVLEGDDVIKIARRMMGKTNPLEADAGTIRAEYAVHTNRNVIHGSDSPESAKREIQLFFEPHEILSYEKAVDIWV
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTN6_CAEEL
Sequence: MTETSTVSIASSAIVCVEADIKGEVIIKEGCVVHPFVVFDATKGPIYVGENNIFEEYAVIRNNSDGQPMIIGDWNIFQVHSKSSAKYVGSRNVIGVHAVLEDGCSVSDDCSVGAKCTVFSHQNLEPSVSVYAATNLSRTTKTPNMTSPHQIEFLRKILPSYHHLYGKKKAVATASASAAQ
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
What are the official names of this protein?
Dynactin subunit 6.
What is the protein family that this protein belongs to?
Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DHRS4_RABIT
Sequence: MASSGVTRRDPLANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTGTVCHVGKAEDRERLVATALNLHGGIDILVSNAAVNPFFGKLMDVTEEVWDKILDINVKAMALMTKAVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQNIRVNCLAPGLIKTSFSKALWEDKAQEENIIQKLRIRRLGKPEECAGIVSFLCSEDASYITGETVVVAGGAPSRL
What is the function of this protein?
NADPH-dependent oxidoreductase which catalyzes the reduction of a variety of compounds bearing carbonyl groups including ketosteroids, alpha-dicarbonyl compounds, aldehydes, aromatic ketones and quinones (PubMed:12604222, PubMed:9880795, PubMed:19056333).  Reduces all-trans-retinal and 9-cis retinal (Probable).  Reduces 3-ketosteroids and benzil into 3alpha-hydroxysteroids and S-benzoin, respectively, in contrast to the stereoselectivity of primates DHRS4s which produce 3beta-hydroxysteroids and R-benzoin (By similarity).  In the reverse reaction, catalyze the NADP-dependent oxidation of 3alpha-hydroxysteroids and alcohol, but with much lower efficiency (By similarity).  Involved in the metabolism of 3alpha-hydroxysteroids, retinoid, isatin and xenobiotic carbonyl compounds (PubMed:12604222, PubMed:19056333).
What are the official names of this protein?
Dehydrogenase/reductase SDR family member 4, NADPH-dependent carbonyl reductase, CR, RACR, NADPH-dependent retinol dehydrogenase/reductase, NDRD, Peroxisomal short-chain alcohol dehydrogenase, PSCD, Short chain dehydrogenase/reductase family 25C member 2, Protein SDR25C2, rabNRDR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: HBA4_BUBBU
Sequence: MVLSAADKSNVKAAWGKVGGHAADYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGAKVANALTKAVGHLDDLPGALSELSDLHAHKLRVDPVNFKLLSHSLLVTLASHLPNDFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-4, Alpha-4-globin, Hemoglobin alpha-4 chain, IIalpha4.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SECA_RICPU
Sequence: MLSILKKLFGTANDRTVKKLFSEITKINSLEPAIQKLSDEELKNKTVEFKEKLKNGATLDDIVYEAFAVVREAAKRVCGMRHFDVQLIGGLILHRGMITEMRTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLARRDSASMGKIYNFLGLSVGCIVGGMPDEVKRAAYNADITHATNNELGFDYLRDNMKYSLQERVLRPFNFAIIDEVDSILIDEARTPLVISGPVNDNAELYGKIDKIVRLLNASDFEKDEKLKTINLTETGITHIESLLSKENIIKPDTSLYDFENLTLVHYVNQALRAHNMFTVNVDYLVREGKVMIIDEFTGRVMEGRRYSEGLHQALEAKENVKIQNENQTLASITFQNYFRNYPKLSGMTGTAMTEAPELKDIYNLDVVAVPTHNKVTRLDLDDEIYGSKKEKYDAILKLIRDCYDRGQPMLVGTISIEKSEELSSVLNKEKIPHKVLNAKFHEQEAFIIAQAGRFKAVTIATNMAGRGTDIMLGGNPEMLIEQLDKEHNYEAKIAEIKAQIAEEKKQVIEAGGLFVIGTERHESRRIDNQLRGRSGRQGDPGKTKFFLSLDDDLMRIFASDRISGVLRTLGLKDGEAIHHPMISRSLEKAQQKVEGHNYEMRKNLLRFDDVMNDQRKIIYEQRTEIIKSKDSHGFLNSTTEELAKKIVLTFMPVGSYREDWDIENLSVELHRVFSIKFDHNVVSKNDVTEEEITKTVIQMAHYIYKSKEEAYSSELMHNAMKYILLTTLDQVWKDHLYSLDHLRQGISLRAYGQKDPLSEYKREAFNLFEQMLNNLKELFIQTVYHFHIDLKNVQKEDVSLEYKKLQKNMRESREDPAFSKYNAGSSLETDLKPVVSRIDPKDRNPDDPTSWGRVSRNELCPCGSGKKYKYCHGANE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MUG_SERP5
Sequence: MELLAPNLRVVFCGINPGLSSAHQGYPFANGSNRFWKVVHQAGFTDTQLAPEQWQQLQDTGCGITALVARPTVAASEVTRDELLSGGEALKEKILRYQPRALAILGKQAFSSAFGVKNAAWGRQEMTIGKTEVWVLPNPSGLNRATLEQLTESYRELFLALK
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_MYCBT
Sequence: MNPSTTQARVVVDELIRGGVRDVVLCPGSRNAPLAFALQDADRSGRIRLHVRIDERTAGYLAIGLAIGAGAPVCVAMTSGTAVANLGPAVVEANYARVPLIVLSANRPYELLGTGANQTMEQLGYFGTQVRASISLGLAEDAPERTSALNATWRSATCRVLAAATGARTANAGPVHFDIPLREPLVPDPEPLGAVTPPGRPAGKPWTYTPPVTFDQPLDIDLSVDTVVISGHGAGVHPNLAALPTVAEPTAPRSGDNPLHPLALPLLRPQQVIMLGRPTLHRPVSVLLADAEVPVFALTTGPRWPDVSGNSQATGTRAVTTGAPRPAWLDRCAAMNRHAIAAVREQLAAHPLTTGLHVAAAVSHALRPGDQLVLGASNPVRDVALAGLDTRGIRVRSNRGVAGIDGTVSTAIGAALAYEGAHERTGSPDSPPRTIALIGDLTFVHDSSGLLIGPTEPIPRSLTIVVSNDNGGGIFELLEQGDPRFSDVSSRIFGTPHDVDVGALCRAYHVESRQIEVDELGPTLDQPGAGMRVLEVKADRSSLRQLHAAIKAAL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: ACTX1_ANTCS
Sequence: CGGAGAKCSTKSDCCSGLWCSGSGHCYHRRYT
What is the function of this protein?
Reversibly inhibits acid-sensing ion channels (ASIC) in rat dorsal root ganglia neurons.  Reversibly inhibits voltage-gated potassium channels (Kv) in rat DRG neurons.
What are the official names of this protein?
Acatoxin 1, Acatx1.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: NUOG_RICTY
Sequence: MIKLIIDGSEIEISEGSTVYQACIQAGKQIPHFCYHARLKIAGNCRMCLVEIEKSQKPVASCAMPVSNGMVIHTDTSMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAFRYGKGTNRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRFANDIAGIEEIGAINRGEHMEVTSYLEQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDSRADEIMRILPSVNEAINEAWISDKNRFCYDGLKYQRLDHPYIRKNGKLVEVSWSEALKTIMDKIKSVKPEKIAAIAGSIVSVEAMFMLKILLQKLGSNNYTVNQFNYKIDTSERGNYLFNTTIVGVEKADLCLLIGANIRQIAPILNSRIGRRVRIGALKVVRIGIGHNQTYKIHDLGNDIKIIEDLAVGTHEYTKAFKEAKYPMIIVGDGVYGRDDGYALLSLIHKVVDKYNMMRDDWQGFNILHNHASIVGGLDIGFNTAIKFEGVKLAYLLGADAIPFDKLKSAFIIYQGHHGDVGAMSADVILPSAAYTEQSGIYVNLEGRPQIAQKAVSPVGRAKEDIEIIKEIAGYLKIDIGMDNLQEVRIRLAKEYNIFANIDKITANRFTQFISIDKLSQEPIAARPINYYMTDVISKNSVTMAKCVEAKEERKRDVAKVFY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit G, NADH dehydrogenase I subunit G, NDH-1 subunit G.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
Protein: SC6A5_XENLA
Sequence: MDYVNVVDGSKKTMNSPEGAAPGLIGATGITNPTPDNDLPLQASNKLTRLSQSTSNDSKLIAAGEPKACDLERSRVGGSCKMTTPGHSNFVLKRDSVEGCPAKNSSMAESNGQTNPMHCRIVPLQSAEGDTNQGFGKNSLEQNNAKGDWVPISQSTVVLGTDGNTSVFPGTLTGDEEGDENKARGNWSNKLDFILSMVGYAVGLGNVWRFPYLAFKNGGGAFLIPYLTMLALAGLPIFYLEVALGQFASQGPISVWKAIPALQGCGIAMLIISVLIAIYYNIIMCYTIFYLFASLVYVLPWASCNNPWNTPDCKDKDRLLLDSCIISSQPNIQIKNSTFCMTAYPNLTMVNFTSHGNKSFVSGSEEYFKYNMLKISAGIEYPGEIRWPLVFCLFLAWIIVYASLAKGIKTSGKVVYSTATFPYVVLVILLFRGVTLPGAGDGIWWFIMPKWEKLMDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNLYRDTLIVTCINSATSIFAGFVIFSVIGFMAHILNVDIEKVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSVSDEFPKLLRTHKPLFTLVCCVAFFIMGFPMITQGGIYMLQLVDNYAASYSLVIIAIFELVGISYIYGLQRFCEDIEMMIGFQPSRFWKICWAFVTPTILTFILGFSFYQWEPMTYGSYHYPSWSMVMGWLMLACSVIWIPIMFVIKMFLAPGTFIERLKLVCSPQPDWGPFLAKHRGERYKNMIDPLGTSSLGLKLPPKDFELGTQC
What is the function of this protein?
Sodium- and chloride-dependent glycine transporter.  Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals.  May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses (By similarity).
What are the official names of this protein?
Sodium- and chloride-dependent glycine transporter 2, GlyT-2, GlyT2, xGlyT2, Solute carrier family 6 member 5.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A5 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS12_CARHZ
Sequence: MPTINQLVRKGREKVAVKSSAPALKGCPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGIEVTAYIGGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDCAGVQNRNQGRSKYGTKRPKAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NQOR_BURA4
Sequence: MAKVLVLYYSSYGHVETMAQHVAEGAKSVPGVEVTLKRVPETIPADQAKAIGVKVDQAAPVATVDELPNYDAIIFGTPTRFGNMAGQMRTFLDQTGCLWMKGALVGKIGSVFASTGTQHGGQETTITSFHTTLLHQGMVIVGVPYACSGLVNMSEITGGTPYGATTLAGADGSRQPSANELDIARYQGKHVAELAVKLAS
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: GET3_CLAL4
Sequence: MDFELEPTLESIIHQDSLKWIFVGGKGGVGKTTTSSSVAVQLALAYPNDEFLLISTDPAHNLSDAFCQKFGKDARKVEGLSNLSCMEIDPDAAMSDLQTQAQQYNNDPNDPLKSMMSDMTGSIPGIDEALSFMEVLKHIKNQRAADDGSESNAIQYKTIIFDTAPTGHTLRFLQLPATLEKLLAKFKDLSGKFGPMLNMLGGGTNQQQDIFSKMNEIQKSVSEVNEQFTNPDMTTFICVCISEFLSLYETERMIQELMSYNMDVNSIVVNQLLFAEEDDCKRCQSRWKMQKKYLDQMGELYEDYHLVKMPLLGSEIRGVNNLKKFSKFLLKPYDPKVDKALVFELEEAK
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting.  Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.  Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
What are the official names of this protein?
ATPase GET3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Golgi apparatus. Note=GET1 and GET2 are required for targeting GET3 to the endoplasmic reticulum.
Protein: Y1238_GLUDA
Sequence: MLIHIPSVLTVEEVAHCRQIMAGAEWVDGRVTAGPQSAMVKNNLQIPLSSDAHREMRDIVLRALGRNPTYNSAALPLRVVPPLFNRYDAGMSFAAHVDNAIRPIHETGARVRTDLSSTLFLSEPDEYDGGELVLHEPGSTQELKLPAGDMVLYPTTALHSVNEVTRGSRLASFFWTQSMIADEARRRIMFELDRTIMDLRTRLPDDDLAVLNLTNCYHNLMRQWCVL
What are the official names of this protein?
PKHD-type hydroxylase GDI1238/Gdia_1949.
Protein: VME1_CVTKE
Sequence: MSSVTTPAPVYTWTADEAIKFLKEWNFSLGIILLFITIILQFGYTSRSMSVYVIKMIILWLMWPLTIILTIFNCVYALNNVYLGFSIVFTIVAIIMWIVYFVNSIRLFIRTGSWWSFNPETNNLMCIDMKGRMYVRPIIEDYHTLTVTIIRGHLYMQGIKLGTGYSLSDLPAYVTVAKVSHLLTYKRGFLDKIGDTSGFAVYVKSKVGNYRLPSTQKGSGMDTALLRNNI
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: ENO_SALPB
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CP6A2_DROME
Sequence: MFVLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFMRLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRVERI
What is the function of this protein?
Is involved in the breakdown of synthetic insecticides and may be involved in the metabolism of insect hormones.
What are the official names of this protein?
Cytochrome P450 6a2, CYPVIA2, Cytochrome P450-B1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.