PharMolix/UniProtQA huggingface dataset:
Protein: BSHC_CHLCH
Sequence: MNTFQLDYRHIQTPKKGFSALFRDYTADAPERETLIAECFHLDYRKSADYYRQLGLLSARTFQRESLVNMLLRQNSRFGGGERQQQAIEKLRSPRCMAVVTGQQLGLFTGTLYTIYKALTAIIVAEQQKSLFPDYDFVPIFWLEGEDHDYDESASTTIFAENQLKHFTHQPYRRLPDQTVANSSFSDDIRTIIDEMVALLPNTPHRTMVAEMLHECYYPGCTFEISFASTMLRLFRNYPLILLSPQESDFKKLAMPIFFKEIESAPAVSYQVIAQSTRLESLGYSAQTKPRAVNFFYVNQHGQRQKVEQPSSDTFQIVPEKQRLSRHQMLELCQDHPERFSPNVVLRPIVQDYVLPTFATIVGPGEINYMAQYRPIYEHFGITMPFLVPRGSFTLVEPKISRVMDKLIHVTGQPGFSRKNIYNAVFSNLQQVKKNAIGEAEHPQLATMFEQAKDEMRQALERLNHTLSTIDPTLEPLLAASIVQSAKLVETIEQKTWKASRRKHEELLEQIQKAETALFPEGVPQERVVNIFYFIAKYGMGILDDLSNLLKGYASDAHIIAELQG
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: PURA_GRAFK
Sequence: MAVDLLLGLQWGDEGKGKIVDVLTSKYDIIARFQGGPNAGHTLEFDGQKHVLHTIPSGIFHDDSINLVGNGVVIDPVIFKRELDNLAKHKIDYKSKLVISRKAHLILPTHRLLDAASEASKGKAKIGSTLKGIGPTYMDKTGRNGLRVGDLELEDWKDRYRALADKHEKMIAFYDVDVQYDLKELEKEFCTAVDTLKELTFIDSEEYLHQAMKSGKSILAEGAQGSLLDIDFGTYPFVTSSNTTAAGACTGLGVAPREIGEAFGIFKAYTTRVGSGPFPTELFDEVGERMGKVGNEFGATTGRKRRCGWLDLVALKYAVQVNGITQLIMMKGDVLSGFDTLKVCTAYKYKGKEITHLPFNIESGNIEPVYTEVKGWEEDLTKMTDASSLPKEFNEYVDFLEKELETPITIVSVGPDRKQTITR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAP18_PONAB
Sequence: MAVESRVTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELTSLVKEVYPEARKKGTHFNFAIVFTDVKRPGYRVKEIGSTMSGRKGTDDSMTLQSQKFQIGDYLDIAITPPNRAPPPSGRMRPY
What is the function of this protein?
Component of the SIN3-repressing complex.  Enhances the ability of SIN3-HDAC1-mediated transcriptional repression.  When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins.  Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets.  The ASAP complex can inhibit mRNA processing during in vitro splicing reactions.  The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis.  Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits the formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function (By similarity).
What are the official names of this protein?
Histone deacetylase complex subunit SAP18, 18 kDa Sin3-associated polypeptide, Sin3-associated polypeptide p18.
What is the protein family that this protein belongs to?
Belongs to the SAP18 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus speckle. Note=Shuttles between the nucleus and the cytoplasm (By similarity). Colocalizes with ACIN1 and SRSF2 in nuclear speckles (By similarity).
Protein: DADD_METST
Sequence: MSETTSILIKDTTILSDKIKKASILIVDNTIEEISNDLSVTDASKVIDGTNKITMPGLVNTHSHVAMTLLRGVGDDEELQTWLNDYIWPKEAKLDEKLVYAGSKLAMAEMIKTGTTTFNDMYFYMEETAKAVEESGIRGVLGYGMIDLFDDEKRKQEIKATKNLIKNSHNTANGRVQVAVAPHAPYTCSKELLSESKKLANKHNLKLHIHVSETQQEVNDLEKQRNQTPFEYLDSIDLLDENTIAAHGVWTTDNEMKLLKEKQVSISHNPSSNMKLASGIAPVSKYIKNDINVAIGTDGVSSNNNLDMFSEMKLTALLQKVNTMNAKTLPAQATFNMATENGARALGINTGSIKEGKLADIVLVNMNVPHMIPVRNPLSNIIYSALGSDVDTVICDGQLLLEDKKLLTINEEDAIYDAKLAAQQL
What is the function of this protein?
Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'-methylthioadenosine, to produce the inosine analogs.  Can also deaminate adenosine.  The preferred substrate for this enzyme is 5'-deoxyadenosine, but all these substrates are efficiently deaminated.  Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions.  May also be involved in the recycling of 5'-deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens.
What are the official names of this protein?
5'-deoxyadenosine deaminase, 5'-dA deaminase, 5'-methylthioadenosine deaminase, MTA deaminase, Adenosine deaminase, S-adenosylhomocysteine deaminase, SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: RRF_GEOKA
Sequence: MAKQVIQQAKEKMDKAVQAFTRELASIRAGRANAGLLEKVTVDYYGVPTPINQLASISVPEARLLVIQPYDKSAIKEMEKAILASDLGLTPSNDGSVIRLVIPPLTEERRRELAKLVKKYSEDAKVAVRNIRRDANDELKKLEKNGEITEDELRSYTDEVQKLTDDHIAKIDAITKEKEKEVMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP1RA_PANTR
Sequence: MGSGPIDPKELLKGLDSFLNRDGEVKSVDGISKIFSLMKEARKMVSRCTYLNILLQTRSPEILVKFIDVGGYKLLNNWLTYSKTTNNIPLLQQILLTLQHLPLTVDHLKQNNTAKLVKQLSKSSEDEELRKLASVLVSDWMAVIRSQSSTQPAEKDKKKRKDEGKSRTTLPERPLTEVKAETRAEEAPEKKREKPKSLRTTAPSHAKFRSTGLELETPSLVPVKKNASTVVVSDKYNLKPIPLKRQSNVAAPGDATPPAEKKYKPLNTTPNATKEIKVKIIPPQPMEGLGFLDALNSAPVPGIKIKKKKKVLSPTAAKPSPFEGKTSTEPSTAKPSSPEPAPPSEAMEADRPGTPVPPVEVPELMDTASLEPGALDAKPVESPGDPNQLTRKGRKRKSVTWPEEGKLREYFYFELDETERVNVNKIKDFGEAAKREILSDRHAFETARRLSHDNMEEKVPWVCPRPLVLPSPLVTPGSNSQERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGAGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNNSGHRPHEGPGGGMGSGHRPHEGPAGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP
What is the function of this protein?
Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex.  The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.  Mediates interaction of WDR82 and PPP1CA.  Inhibitor of PPP1CA and PPP1CC phosphatase activities.  Has inhibitory activity on PPP1CA only when phosphorylated.  Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 1 regulatory subunit 10, MHC class I region proline-rich protein CAT53, Protein FB19.
What are the subcellular locations of this protein?
Nucleus. Note=Found in discrete nucleoplasmic bodies and within nucleoli. Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase (By similarity).
Protein: GLRX3_ECOLI
Sequence: MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEMIKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLK
What is the function of this protein?
The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase.  In addition, it is also involved in reducing some disulfide bonds in a coupled system with glutathione reductase.
What are the official names of this protein?
Glutaredoxin 3, Grx3.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
Protein: RS11_CAUVC
Sequence: MAKEPARVKRRERKNITSGVAHVNASFNNTMITITDAQGNTISWSSAGMMGFKGSRKSTPYAAQMAAEDAGKKAAEHGVKTLEVNVSGPGSGRESALRALQAAGMTITTIRDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: H2A_HIPHI
Sequence: MSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAHRVGAGAPVYL
What is the function of this protein?
Hipposin shows strong antimicrobial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. SUBCELLULAR LOCATION: [Hipposin]: Secreted.
Protein: PALA_DEBHA
Sequence: MNTNLLYIPYRETDIIDLGNELRNIIKMEYFQPSSNFDRDLQAVRNLRNNISNLKNEQVNNNDETVCVQYYHQLSNVIKKFPDECVEFSWYGTLGYGRSGPTRSRSLRIEQLNILYQLGSYFSQAALMESRYSDEGLKKSCSYLQAAAGCFNSMILQIQKENEKETGMIRIPRDLQPETLQFLKSLMIAQAQETIWQKSLASGMKDSVIARLSIQTSEYYSTAAKYGNSSEFIKLEWINHVTVKQFHFKAAAHYRVSILNHEGFKYGEQVASLQVALSSCDSAFRKKKYVNDFVIEDLQGLTETIKSTLRVAEKDNDLVYLKPVPKENDLAPIPGASLVKPILPPAIESFDDSSVLFKELLPYLIVQVGQAYRERQDSFIRDSFIDPIQSLNKIMYKFITERNLPASIDTIQKPENLPESIIQHSQEIISYGGTKLIEDSLNEIAKLTLESRHILEGCQERLKIEADEDDIMRERQGSQRWARPKSSEASSEFINKINKMEQYLDQAKEGDQFIISQYHEIEPYLQLYCGGYKELIQFIPNSTYVKLDTKINEIIIKLRELINEVSRIENQRKQFLTRIEIKARNNNILPSIIDSFKKKQRKLYEENAAIDERSFEDVYAKHITMFNSDLRFLEDSKHAQIALEGNIDDLNQEFESEYQHTNNESQYKRQEVLQTLENVYTKYLELISNLNEGSKFYSDFIIKSNSVLKECDEYVYHRRVEGRELEMFLNNQAVPVESVGSQQSAPDFPPQPMGGTWNPNNGIKFG
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.  May act as a scaffold protein that recruits the calpain-like protease RIM13 via VPS32 to its substrate RIM101 (By similarity).
What are the official names of this protein?
pH-response regulator protein palA/RIM20.
What is the protein family that this protein belongs to?
Belongs to the palA/RIM20 family.
Protein: SELU_SALNS
Sequence: MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: RSMJ_AERHH
Sequence: MQILLEDPAKAPQAEALASQLGQTDLPQFALVFTAARLELRKLDEPKLGAVYVDFVEGAVAHRRKFGGGRGQSIAKAVGLKAGAMPRVVDATAGLGRDAFVLASLGCKVTMIERSPVVAALLQDGLARAALDPEIGPWVRERMQLRHGPAVETLLGLTERPDVIYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADALLPAALAMADKRVVVKRPDYAGWLNEHKPSMAIETKSNRFDVYVMAALAG
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_ACIC5
Sequence: MVGQRIRIRLKAYDYRVLDTSTGEIVDTAKRTGAQVAGPIPLPTVKNKYCVLRSPHVDKKSREAFEIRTHKRLIDILEPTQQTVDALMRLDLPAGVDVEIKAFEK
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: BOA7_BOTFB
Sequence: MYQRLKEINFRKPLELEWNSIFLILGFFVLAAILIAWTQRPDEELLLERLKDLDLPIVGVGPNINVSESLEIGTQTYPNSPYVVPADRVPIVILPNSAINIIKSLPEAKISFEKEVYARHLAHLLLKKDQKIFSEPILNSIKQDLTRNISKTLDTLWDEVDYAFEKNIGTLPDDDDGWKNVSVYGKVLNVVALLSGRVFVGAPLCRDEEWIKATIAYTIILGVTVGMLWKRPWWQRKILAPLYFRTLVGVHKKAEELLKPLLEREAALDPSEWEKKAGEQNDGQLIRWLLSHTPQKGGKIDVKQLAHDQLTVSLAAIHTTSITISHLLYDLATYPEHVAPLRTELESVIADHKTAGGNGKLSKVELTKLWKMDSFIKESQRLNPPILVQMRRYLTSPLALPSGHILPSGTFCGVDAQMTNRTVPYYEASPITHQQTPFDTFDGFRFSKLRSVPGNENRYQFVTSSTESLNFGHGTHACPGRFFASNEIKIAFAEVLLKWDVRLKPGEGRPANLYTDTNVMPNMKGEVQMRRRELI
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster B that mediates the biosynthesis of botcinic acid and its botcinin derivatives, acetate-derived polyketides that contribute to virulence when combined with the sesquiterpene botrydial (PubMed:21722295).  Botcinic acid and its derivatives have been shown to induce chlorosis and necrosis during host plant infection, but also have antifungal activities (PubMed:21722295).  Two polyketide synthases, BOA6 and BOA9, are involved in the biosynthesis of botcinins.  BOA6 mediates the formation of the per-methylated tetraketide core by condensation of four units of malonyl-CoA with one unit of acetyl-CoA, which would be methylated in activated methylene groups to yield a bicyclic acid intermediate that could then either be converted to botrylactone derivatives or lose the starter acetate unit through a retro-Claisen type C-C bond cleavage to yield botcinin derivatives (PubMed:23203902).  The second polyketide synthase, BOA9, is probably required for the biosynthesis of the tetraketide side chain of botcinins (Probable).  The methyltransferase (MT) domain within BOA6 is probably responsible for the incorporation of four methyl groups (Probable).  The trans-enoyl reductase BOA5 might take over the enoyl reductase function of BOA6 that misses an ER domain (Probable).  The monooxygenases BOA2, BOA3 and BOA4 might be involved in further hydroxylations at C4, C5 and C8, whereas BOA7, close to BOA9, could potentially be involved in the hydroxylation at C4 in the side chain of botcinins (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase BOA7, Botcinic acid biosynthesis cluster B protein 7.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS15_STRM5
Sequence: MSIDTQKVIEDNKRSSADTGSPEVQVALLTARIELLTGHFKTHKKDHHSRRGLLQMVNRRRSLLDYLKKKDVERYKALIEKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CFI_TOBAC
Sequence: MESITIENYVFPSTMVNPPGSTNTFFLAGAGNRGLEIEGKFVKFTAIGVYLEESALPFLAAKWKSKSSEELANSLDFFRDIVTGPFEKFTRVTMILPLTGKQYSEKVAENCVAHWKAIGTYTDAESQAIEKLLNIFQNETFPPGASILFTQSPVGALTISFIKDDSITGTGNAVIENKQLSEAVLESIIGKHGVSPAAKCSIAERVSGLFKKSYADASVFEKPGIEKSSDPVIEEKPTIPEIGV
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin.
What are the official names of this protein?
Chalcone--flavanone isomerase, Chalcone isomerase.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: SYE_SHEHH
Sequence: MTIKTRFAPSPTGFLHVGGARTALYSWLYARANQGEFVLRIEDTDIERSTPEACAAILEGMEWLNLNWDEGPYYQTKRFDRYNEIIAQMLEQGTAYKCYCSRERIETMREEQAANGEQQKYDGCCRDKAPRDTDEPFVVRFKNPTEGSVVFDDHVRGRIEFANSTLDDLIIARTEGTPTYNFCVVVDDWDMGITCVVRGEDHINNTPRQINILKALGAPVPEYAHVAMILGDDGAKLSKRHGAVGVMQYRDDGFLPEALLNYLVRLGWSHGDQEVFSIEEMKQFFSLDDINKAASAFNTDKLIWLNQHYIKEMDPEYVASHLEWHMADQNIDTSNGPKLSEVVSALSERAKTLKELAASSRYFFEDFAEFEETAAKKHLRGVALEPLTLIQSKLAALNEWTLEAIHQAIEDTASELDVGMGKVGMPLRVAVTGAGMSPAVDLTLFLVGKARCEQRISKAIEFVANRVNS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CISY_RICC1
Sequence: DSEFAELKIRGKIFKLPILKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDIKDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLVNERLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNPLDFTENFLHMMFATPCTKYTVNPIIKNALNKIFILHADHEQNASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAVINMLKEIGSSEYIPKYIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKALGQLDNNPLLQIAIELEAIALKDEYFIERKLYPNVDFYSGIIYKAMGIPSQMFTVLFAIARTVGWMAQWKEMHEDPEQKISRPR
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: CC28A_HUMAN
Sequence: MPRAEPRATLGEQEKAGLPLGAWRLYLLRHFRKQTELRRSGSRDVTGALLVAAAVASEAVGSLRVAEGGPNTLLLQVLRSWPWCNKELKTMEERKVKRRSPKSFSAHCTQVVNAKKNAIPVSKSTGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQSTPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTASDSNLDRLLSDLEELNSSIQKLHLADAQDVPNTSAS
What are the official names of this protein?
Coiled-coil domain-containing protein 28A, CCRL1AP.
Protein: RL22_KLEP3
Sequence: METLAQHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVAKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GP183_MOUSE
Sequence: MANNFTTPLATSHGNNCDLYAHHSTARVLMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSMNLVISDILFTTALPTRIAYYALGFDWRIGDALCRVTALVFYINTYAGVNFMTCLSIDRFFAVVHPLRYNKIKRIEYAKGVCLSVWILVFAQTLPLLLTPMSKEEGDKTTCMEYPNFEGTASLPWILLGACLLGYVLPITVILLCYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFILCFTPYHVAIIQHMIKMLCSPGALECGARHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMKMLKRQVSVSISSAVRSAPEENSREMTESQMMIHSKASNGR
What is the function of this protein?
G-protein coupled receptor expressed in lymphocytes that acts as a chemotactic receptor for B-cells, T-cells, splenic dendritic cells, monocytes/macrophages and astrocytes (PubMed:19597478, PubMed:19615922, PubMed:21844396, PubMed:21796211, PubMed:21796212, PubMed:27147029).  Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols (PubMed:21796211, PubMed:21796212).  Mediates cell positioning and movement of a number of cells by binding the 7-alpha,25-OHC ligand that forms a chemotactic gradient (PubMed:21796211, PubMed:21796212, PubMed:27147029).  Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses (PubMed:21796211, PubMed:21796212).  Collaborates with CXCR5 to mediate B-cell migration; probably by forming a heterodimer with CXCR5 that affects the interaction between of CXCL13 and CXCR5 (PubMed:21948984, PubMed:22913878).  Guides B-cell movement along the B-cell zone-T-cell zone boundary and later to interfollicular and outer follicular regions (PubMed:19615922, PubMed:19597478, PubMed:21844396).  Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (PubMed:19615922).  Also acts as a chemotactic receptor for some T-cells upon binding to 7-alpha,25-OHC ligand (PubMed:27147029).  Promotes follicular helper T (Tfh) cells differentiation by positioning activated T-cells at the follicle-T-zone interface, promoting contact of newly activated CD4 T-cells with activated dendritic cells and exposing them to Tfh-cell-promoting inducible costimulator (ICOS) ligand (PubMed:27147029).  Expression in splenic dendritic cells is required for their homeostasis, localization and ability to induce B- and T-cell responses: GPR183 acts as a chemotactic receptor in dendritic cells that mediates the accumulation of CD4(+) dendritic cells in bridging channels (PubMed:23682316, PubMed:23502855).  Regulates migration of astrocytes and is involved in communication between astrocytes and macrophages (PubMed:25297897, PubMed:27166278).  Promotes osteoclast precursor migration to bone surfaces (PubMed:26438360).  Signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha (By similarity).  Signals constitutively also via MAPK1/3 (ERK1/2) (By similarity).
What are the official names of this protein?
G-protein coupled receptor 183, Epstein-Barr virus-induced G-protein coupled receptor 2 homolog, EBI2, EBV-induced G-protein coupled receptor 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYC_LISMH
Sequence: MSIQIFNTLKREKEPFKPLKDGEVKMYVCGPTVYNYIHIGNARPIIVFDTVRRYFTYRGYDVKFVSNFTDVDDKLIRAANELKLTVPEVADRFIGAYFDDVDQLNVAKATVNPRVTENMDEIIQLISTLIEKGYAYESAGDVYFRTKKFKDYGKLSGQELSELQHGARVEYNERKQDELDFTLWKAAKPGEIFWESPFGNGRPGWHIECSALAKKYLGDTIDIHAGGQDLVFPHHEDEIAQSEAATGKTFANYWMHNAFLNIDGEKMSKSLGNFITLHDVLKDNDPNVIRFFMLSVHYRKPITLNDAILEDAKNGLERLMIAYQNIDHRIQTDDGEYVEEAHEDEWLEQLTELKQAFEDDMDDDFNTANAITTFHELAKRANIYLAKETVSINVLREFLSMMRLFAEVLGLKLENTQTDSLDDSEVEALIEERLQARNERNFARADEIRDILKEKNIILEDTAQGTRFRRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.