PharMolix/UniProtQA huggingface dataset:
Protein: IF1_BART1
Sequence: MSKEEVLEFSGVVTELLPNAMFRVKLENDHEIIAHTAGRMRKNRIRVLAGDKIMVEMTPYDLTKGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_AEDAE
Sequence: MEVEESKNDASVVASPAPTKLPQKRFYRQRAHSNPIADHSFDYPIHPDDYDWSQHYPTIGDKRVEFADIGCGYGGFLVTLGEMFPDKFAVGMEIRVKVSDYVMDRIQALRKLNEGQYENIACIRTNAMKYLTNFFHKGQLEKMFFLYPDPHFKKAKHKWRIINSALLSEYSYVLRQGGLIYTITDVKDLHEWMCKHIEQHPAFERLTDDEVKADVLSEKLLDSSEEGKKVTRNKGDKFVAIFRKI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYT_NATPD
Sequence: MSEIVVTLPDGSELEMESGSTVEDVAYEIGPGLGDDTVAGVVDGELVDKAEQLTDDCELVIVTDQSDEYLQVLRHSAAHVFAQALQRLHPEAKLAIGPPTEEGFYYDVTGVDLDADDLEAIEAEMETIIEADHDIERAERSREEAFEIYEDNPYKRDILETEAADEDPVSFYTQDDWQDLCQGPHVDSTGEIGAVELLNIAAAYWRGDEDNETLTRVYGTAFESESDLEGFLQRREEAKKRDHRKLGQELDLFSIPDVTGPGLPLYHPNGKAVLRELEDFVDQLNDDQGYEFVETPHLFRTELWKQSGHYENYVDDMFLLDVNDEEYGLKPMNCPGHATIFNQGNWSYRDLPVRYAENGKVYRKEQRGELSGLSRVWAFTIDDGHLFVERDAIEQEVNVIMDQIEEVLDTFDLDYEVALATRPEKSVGSDEIWEQAQTQLRSVLESSGMDYDIESGDGAFYGPKIDFAFEDALGRNWDGPTVQLDFNMPERFDLTYTGEDNEEHRPVMIHRALYGSYERFFMVLIEHFDGNFPTWLAPEQVRILPVSDDNIGYAKQLKNRYLDDFRVEIEDRSWTVGKKIQTAHDDRVPYMLVVGDNEEEAGTVSVRDRFEDERKDVDVETFRDHLASEVEEKRVEPDFVDE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_BARQU
Sequence: MNVLSIMDDLKRRMDGAISAFQHELGGLRTGRASASLLEPLTVEAYGSVVHINQVANISVPEPRMLSVSVWDKTMVGAVERAIRDSGLGLNPITDGMNLRIPLPELNEERRKELVKIAHQYAEQARVATRHVRRDGMDNLKKLEKEGEISQDEAHGLSEKVQKLTDETIANIDKILAVKESEIMHV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDZ11_DANRE
Sequence: MDQKIPYDDYQLPVVFLPSYENPPAWIPPQERIHHPDYNNELAQFLPRTIVLKKPPGAQLGFNIRGGKASQLGIFISKVVPDSDAHRAGLQEGDQVLSVNEVDFQDIEHSRAVEILKTAREILMKVRYFPYNYQRQKERTVH
What are the official names of this protein?
PDZ domain-containing protein 11.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_MYCVP
Sequence: MSSTDLSAKLFADACSVIPGGVNSPVRAFSSVGGTPRFITSANGCWLTDADGNRYVDLVCSWGPMILGHAHPAVVEAVQRAAADGLSFGAPTPSEAELAREIIDRVAPVELIRLVNSGTEATMSAIRLARGFTGRAKIVKFSGCYHGHSDALLADAGSGVATLGLPSSPGVTGAAAADTIVLPYNNVPAVEEVFGRFGDEIACVITEASPGNMGTVPPLPGFNAELRRITAAHGALLILDEVMTGFRVSRAGWYGVDPVEADLFTFGKVMSGGLPAAAFGGRAEVMNRLAPLGPVYQAGTLSGNPVAMAAGLATLRAADDAAYATLDVNADRLAGLIGDALTEAGVAHQIPRAGNMFSVFFGAEPVTDFAAARATETWRFPAFFHGLLDAGVYPPPSAYECWFVSTALDDDAFDKIAAALPGAARAAAQATA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YUBG_ECO57
Sequence: MNENTTLNALICRHARNLLLAQGWPEETDVDQRNPKYPGWISIYVLLDAPRLATLLVNRHGGVLPPHLASAIQKLTGTGAELVLSGSQWQSLPVLPADGTQVSFPYAGEWLTEDEIRAVLAAVRDAVRSVSCRVAEDTRRIRAALTTTGQTLLTRQTRRFRLVVKESDHPCWLDEDDENLPVVLDAILNRGARFSAVEMYLVSDCIEHILSSGLACDVLRIPDEPPRRWFDRGVLREVVREARNEIRSMADALAKIRK
What are the official names of this protein?
Uncharacterized protein YubG.
Protein: ADDB_STRPN
Sequence: MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKERAVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDLRVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQGQLAQESQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVIGAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLESSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILLGDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLLRTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAPLETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVLEQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYAIGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSARKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSLVAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALYPAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQLPNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIETIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPHFFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKYQGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYTENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREELNR
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: DPO3B_ACTPL
Sequence: EEIIDVAYQSPEMEVGFNVSYLLDVLNTLKCERVRFNLVDASSSCLIEDCDNSTAEYVIMPMRL
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_BREBN
Sequence: MAMITDIYAREIMDSRGNPTVEVEVYLEDGSMGRADVPSGASTGAYEAVELRDGDKSRYLGKGVLKAVENVNEIIAPELIGMDALDQVGIDMAMIQLDGTPNKGKLGANAILGVSMAVARAAAESLGVPLYNYLGGFNARMLPVPMMNILNGGKHADNTVDIQEFMVMPVGATSFKEALRTGAEIFHSLKKVLGEKGLSTAVGDEGGFAPNLKSNEEAITTILDAIKAAGYEPGKDVFLALDVAATEMFKDGKYHFEGEGVVKTTEEMIAFYEDLVNKYPIISIEDGLSEDDWDGWKALTDKLGSKVQLVGDDLFVTNTERLARGIETSTGNSILVKVNQIGTLTETFEAIEMAKLAGYTAVISHRSGETEDSTISDIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELADTARFGGRSAFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CGAT1_HUMAN
Sequence: MMMVRRGLLAWISRVVVLLVLLCCAISVLYMLACTPKGDEEQLALPRANSPTGKEGYQAVLQEWEEQHRNYVSSLKRQIAQLKEELQERSEQLRNGQYQASDAAGLGLDRSPPEKTQADLLAFLHSQVDKAEVNAGVKLATEYAAVPFDSFTLQKVYQLETGLTRHPEEKPVRKDKRDELVEAIESALETLNSPAENSPNHRPYTASDFIEGIYRTERDKGTLYELTFKGDHKHEFKRLILFRPFGPIMKVKNEKLNMANTLINVIVPLAKRVDKFRQFMQNFREMCIEQDGRVHLTVVYFGKEEINEVKGILENTSKAANFRNFTFIQLNGEFSRGKGLDVGARFWKGSNVLLFFCDVDIYFTSEFLNTCRLNTQPGKKVFYPVLFSQYNPGIIYGHHDAVPPLEQQLVIKKETGFWRDFGFGMTCQYRSDFINIGGFDLDIKGWGGEDVHLYRKYLHSNLIVVRTPVRGLFHLWHEKRCMDELTPEQYKMCMQSKAMNEASHGQLGMLVFRHEIEAHLRKQKQKTSSKKT
What is the function of this protein?
Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA).  Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains.  Important role in chondroitin chain biosynthesis in cartilage formation and subsequent endochondral ossification (PubMed:11788602, PubMed:12163485, PubMed:12446672, PubMed:17145758, PubMed:31705726).  Moreover, is involved in the metabolism of aggrecan (By similarity).
What are the official names of this protein?
Chondroitin sulfate N-acetylgalactosaminyltransferase 1, CsGalNAcT-1, Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1, Beta4GalNAcT-1.
What is the protein family that this protein belongs to?
Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: DTD_PEDPA
Sequence: MRVVIQRVSKASVTIEENVVGKVGPGFMLLVAFNDEDTDADLDFAVRKIVNMRIFEDEQAKMNLSINDVKGAILSVSQFTLFASTKKGNRPSFTKSGNPELASKLYDQFNAKLRATGIEVQTGQFGADMQVELVNDGPVTIVLDTQNKE
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLMA_SHEB8
Sequence: MAVSPKINRREHILQCLAQMLETNPGQRITTAKLASEVGVSEAALYRHFPSKARMFEGLIEFIEESLLSRINLIMDDEKDTMKRCQLVLQLLLIFAERNPGISRVLNGDALLGENERLRSRISNLFAKIETQLKQILREKTLREGKGFNLDEAILANLLLAFAEGRIAQFVRSEFKLKPTTHFDEQWRFIQHQLLQS
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: UCP5_HUMAN
Sequence: MGIFPGIILIFLRVKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI
What is the function of this protein?
Participates in the mitochondrial proton leak measured in brain mitochondria.
What are the official names of this protein?
Brain mitochondrial carrier protein 1, BMCP-1, Mitochondrial uncoupling protein 5, UCP 5, Solute carrier family 25 member 14.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: SUI1_THEON
Sequence: MPRIVNPLDEMLFKEVLKEQQRIRVYIEKARYGKLKTIIEGIDEKEFDLEDIAKKLKAKLACGGTVKKGRIELQGDHREKVKKLLADLGFSEDLIEIE
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: NADE_METAC
Sequence: MDFEKAQNRIIEFIRNETDKAGVDGAVVGISGGIDSALTATLTVEALGKERVLGLHMPESSLTPAVDSEDAKILADWLGIEYRTIDISGIVSAFMASIPESESSDRLTRGNLKARTRMSLLYFHANRLNRMVVGTGNKTEILLGYYTKYGDGGVDLEPIGGIYKTEVWELSRRLGIPDPLITKKPSAGLWTGQTDEAELGISYLKVDDVLRMIEEGAEQEKILKDTGISIEQLNSVTRRIERNEHKRKSPPVPELY
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: PPID_DEBHA
Sequence: MSDKLNRPKVFFDISADGKPKGRVVFELYNDVVPKTAENFRALCTGEKGASESSGKQLHYKGSIFHRIIKDFMCQGGDFTHGSGIGGESIYGEKFEDENFQLTHDKPFLLSMANAGANTNGSQFFITTVPTPHLNGKHVVFGEVIQGKSIVRQLERCDKGENDKPVEDWIISDCGELPSDYVPVPTSVDDGTGDIYEEVMADDDNINVNDPESVFKAVTTLKDIGTKQLKDGNVAAAYEKYNKASGFLNDYFPEDLSEENLSKLHALKLSCYLNAALVALKLKDGKKTINAASNALEVEAIDDKSKTKALYRKGMGYLLAKDEESAQKSLEEALQLSPEDGAIIKGLQDVKTTIKARRDKQKKAMSKFFS
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase D, PPIase D, Rotamase D.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTNJ_NECSZ
Sequence: MSNKHSACQVQFRVIVVGAGIGGLSAAVALANRGHSVLVLESTTKLSHVGAGVALPPTTRKWYESEGVLRAESGCIPLDGIELRKWDTGELVTRTAANPIGKQNAIHHGDMQQALLARAAQLDNISIRLGARVMDIDIDSNTVLLHNGEQVEGDVIIAADGVKSVIKPKICPPGASKAQSTGEAAYRFTLARDLLKDDEELLDLVQRSWATRWDGPSRHVVAYPVRNHQLLNVVLIHPDDGNTEESWTTVADKQDVIEHYQDWNLTLNKLIHLAPTQVPNFRMFLYPPSPVWVKGSTILLGDACHAMLPYLGQGVGQAADDAVAIATVLSTIEHREQLPLALQAYEVSRKSRVEQIQAATYQAREHLHLKDREAQAARDLQRKSASESNQNSDVVKMQHSYWVWDAAKVAQIALTELITG
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of the meroterpenoids nectripenoids A and B, as well as cochliquninone D and isocochliquninone E (PubMed:29797385).  The pathway probably begins with the HR-PKS ntnH that catalyzes two chain-extension steps to form a reduced triketide, which then primes the SAT domain in the NR-PKS ntnG to initiate three more cycles of extension to give a linear hexaketide corresponding to the polyketide part of nectripenoids (Probable).  The FAD-dependent monooxygenase ntnJ then performs an oxidative decarboxylation at C11 of the ntnH/ntnG product, via an electrophilic aromatic hydroxylation with concomitant ipso-decarboxylation (Probable).  The membrane-bound polyprenyl transferase ntnF then introduces a farnesyl group before the FAD-dependent monooxygenase ntnK functions as the first epoxidase on terminal C12'-C13' olefin, followed by a second epoxidation on C7'-C8' catalyzed by ntnA (Probable).  The terpene cyclase/mutase ntnI then initiates the sequential tricyclic ring formation through protonation of the terminal epoxide and catalyzes the regioselective and stereoselective 6/6/6-tricyclic ring formation (Probable).  The cytochrome P450 monooxygenase ntnM may then hydroxylate C1' (Probable).
What are the official names of this protein?
FAD-dependent monooxygenase ntnJ, Nectripenoid biosynthesis cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DRTS_PLAVI
Sequence: MEDLSDVFDIYAICACCKVAPTSEGTKNEPFSPRTFRGLGNKGTLPWKCNSVDMKYFSSVTTYVDESKYEKLKWKRERYLRMEASQGGGDNTSGGDNTHGGDNADKLQNVVVMGRSSWESIPKQYKPLPNRINVVLSKTLTKEDVKEKVFIIDSIDDLLLLLKKLKYYKCFIIGGAQVYRECLSRNLIKQIYFTRINGAYPCDVFFPEFDESQFRVTSVSEVYNSKGTTLDFLVYSKVGGGVDGGASNGSTATALRRTAMRSTAMRRNVAPRTAAPPMGPHSRANGERAPPRARARRTTPRQRKTTSCTSALTTKWGRKTRSTCKILKFTTASRLMQHPEYQYLGIIYDIIMNGNKQGDRTGVGVMSNFGYMMKFNLSEYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMHDNYEDKGVDQLKNVIHLIKNEPTSRRIILCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHILGNAHVYNNHVDSLKVQLNRIPYPFPTLKLNPEVKNIEDFTISDFTIENYVHHDKITMEMAA
What is the function of this protein?
Bifunctional enzyme.  Involved in de novo dTMP biosynthesis.  Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.
What are the official names of this protein?
Bifunctional dihydrofolate reductase-thymidylate synthase, DHFR-TS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thymidylate synthase family.
Protein: SYP_BACTN
Sequence: MAKELKDLTKRSENYSQWYNDLVVKADLAEQSAVRGCMVIKPYGYAIWEKMQRQLDDMFKETGHVNAYFPLLIPKSFLSREAEHVEGFAKECAVVTHYRLKNAEDGSGVVVDPAAKLEEELIIRPTSETIIWNTYKNWIQSYRDLPILCNQWANVFRWEMRTRLFLRTAEFLWQEGHTAHATREEAEEEAIRMLNVYGEFAEKYMAVPVVKGVKSANERFAGALDTYTIEAMMQDGKALQSGTSHFLGQNFAKAFDVQFVNKENKMEYVWATSWGVSTRLMGALIMTHSDDNGLVLPPHLAPIQVVIVPIYKNDEQLKQIDAKVEGIVAKLKALGISVKYDNADNKRPGFKFADYELKGVPVRLVMGGRDLENNTMEVMRRDTLEKETVTCDGIETYVQKLLEEIQANIYKKALDYRNSKITTVDTYEEFKEKIEEGGFILAHWDGTTETEEKIKEDTKATIRCIPFDSYVEGDKEPGKCMVTGKPSACRVVFARSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_STRZJ
Sequence: MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: Y4QB_SINFN
Sequence: MPKLIWIPESVVEAMLKDASRWHDLETGGTFMGYWSDANVAVITKMIDGGSEAIRTRKSFSPDREWEQSEIDRHYRVSGRVDTYIGDWHTHPNAQSGEPSWTDRRCLRTIIRSPEARAPRPVMILLCGGPENWLPHAWIGQLTRRALLFERVETTAATISTYKT
What are the official names of this protein?
Probable metalloprotease y4qB.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67B family.
Protein: COA6_BOVIN
Sequence: MAAPTMKERQACWGARDEYWKCLDENTEDASKCKKLRSSFESSCPQQWIKYFDKRRDYLKFKEKFEAGDFQPSKMTAKS
What is the function of this protein?
Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2.  Thereby, may regulate early steps of complex IV assembly.  Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis.  May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.
What are the official names of this protein?
Cytochrome c oxidase assembly factor 6 homolog.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6B family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: DPO3A_NEIMA
Sequence: MTEPTYIPLRLHTEFSITDGMVRIKKLIAKAQEYGLPALGISDLMNEFGLVKFYKACRSAGIKPIGAADVRIGNPDAPDKPFRAMLIIRNDAGYLRLSELLTAAYVGKDRNVHHAELNPEWLENGDNSGLICLSGAHYGEVGVNLLNGNEDAARAAALKYAAWFPDAFYLELQRLPERPEWEACVSGSVKLAEELGLPVVATHPTQFMSRDDFNAHEARVCIAGGWVLTDKKRPRDFTPSQFFIPPETMAERFSDLPEALENTVEIAKRCNLHITLGKNFLPLFPTPDGLSLDDYLVKLSNEGLQERMVQLYPDEAERAAKMPEYQERLDFELNIIIQMKFPGYFLIVQDFINWAKTHGCPVGPGRGSGAGSLVAYSLKITDLDPLKYALLFERFLNPERVSMPDFDVDFCQANRGRVIEYVREKYGAEAVSQIVTFGTMSSKAVIRDVGRVLELPFTLCDKLSKLIPLEANKPLGLDDAMKAEPQIQELIEAEEADELITLAKKLEDLTRGLGMHAGGVLIAPGKISDYSPVYQADESASPVSMYDKGDVEDVGLVKFDFLGLRNLTIIEMAQNNIKNTTGDIVDVGTIPLDDQTAYQIFRDANTTAVFQFESTGMKKMLKTAHTTKFEELIAFVSLYRPGPMDNIPDFVARMKGQEFQYIHPLLEGILAPTYGIMVYQEQVMQAAQIIGGYSLGGADLLRRAMGKKKPEEMVKHREIFAEGAAKQGISREKSDEIFNYMEKFAGYGFNKSHAAAYALISYQTAWLKAHYPAEFMAATMSSELDNTDQLKHFYDDCRANGIEFLPPDINESDYRFTPYPDMKIRYALGAIKGTGEAAVESITSARQSGGKFTGLLDFCERVGKEHMNRRTLEALIRGGAFDSIEPNRAMLLANIDLAMNNADQKAANANQGGLFDMMEDAIEPVRLIDAPMWSESEKLAEEKTVIGFYLSGHPFGPYAQEVRQIAPQKLSKLKPQDSVRLAGFVTAVRTMMGKRGKIAFVSLEDLSGQVEIMVGGQTLENCADCLKADQVLIIESKVSRDDYGGGDGLRILANQVMTLQTARERYARSLSLALAPHHDIGELVQLLAAHQLPDTPRIPLQLSYANEKASGRLQVPPKWTVTPSSALFGELETLLGSRSVRVNW
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPC_SERMA
Sequence: MKLRVLSLMVPALLVAGTAGAAEIYNKDGNKLDLYGKVDGLHYFSSNNGVDGDQSYMRFGLRGETQISDQLTGYGQWEYQANLNHAENQDNKNFTRYGFAGLKFGDYGSFDYGRNTGVLYDVAAYTDLQPEFDGMTYGADQFMFQRSSGLATYRNNDFFGLVDGLNFALQYQGKNGNGEETNNGRDVLGQNGEGYGMSMSYDMGYGISAAGAFFNSRRTSEQNGANGHQNIMGRGDKAEGYSGGLKYDANDVYLAVMFTQSYNAARFGSSDSSVYGYANKAQSFEAYAHYQFDFGLRPFVGYNQTKGKDLGRAGNGKDYGDQDLVKFVDLGATYFFNKNMSTYVDYKINLVDNNDFTDAAGINTDNVVAVGLVYQF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane porin C, Outer membrane protein C, Porin OmpC.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: PDXH_NOSS1
Sequence: MDRTIADLRKDYTLEGLSEIEVDPNPFIQFKKWFEQALAAQLPEPNAMTIATSTPDGQPSARMVLLKDFDEQGFVFFTNYNSRKGQELAENPQAALVFWWAELERQVRISGRVEKVSESESDYYFYSRPANSRLGAWVSNQSEIIASREVLEQRMQEFQHKYENQEIPRPAHWGGLRVIPSEIEFWQGRSSRLHDRLLYTLLNDHSWEIHRLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: CB066_HUMAN
Sequence: MIIDSSRIPSFTQLHSTMTRAPLLLLCVALVLLGHVNGATVRNEDKWKPLNNPRNRDLFFRRLQAYFKGRGLDLGTFPNPFPTNENPRPLSFQSELTASASADYEEQKNSFHNYLKG
What are the official names of this protein?
Uncharacterized protein C2orf66.
What are the subcellular locations of this protein?
Secreted.