PharMolix/UniProtQA huggingface dataset:
Protein: RPOC1_PHAAO
Sequence: MIDQYKHQQLRIGSVSPQQIRAWAKKILPNGEIVGEVTKPYTFHYKTNKPEKDGLFCERISGPIKSGICACGNYRGIGTEKEDPKFCEECGVEFVDSRIRRYQMGYIKLTCPVTHVWYLKRLPSYIANLLDKPLRELEGLVYCDFSFARSIAKKPTFLRLRGSFEYEIQSWQYSIPLFFTTQGFETFRNREISTGAGAIREQLADSDLRIITDNSLLEWKELGDEESAGNEWEEKKIRRRKDFLVRRIELAKHFLRTNVDPEWMVLCLLPVLPPELRPIIQIDGGKLMSSDINELYRRVIYRNNTLTDLLATSRSTPGELVMCQEKLVQEAVDTLFDNGIRGQPMRDGHNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPLLSLHQCGLPREIAIELFQAFVIRGLIRQDVASNTGIAKSKIREKEPIVWEILQEVMQGHPVLLNRAPTLHRLGIQAFQPILVEGRAICLHPLVCKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSPAIGDPVSVPTQDMLIGLYVLTIGNPRGICANRYNQSNSNCRNYKKEKVYKNDFKYTKELYFSSSYDALGAYRQKRIHLDSPLWLRWRLDQRVVGSREVPIEIQYESFGNYNEIYKHYQIIGSVKIEICCIYIRTTAGHISFYREIEEAIQGFWRAYS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CHEB3_PSEU2
Sequence: MAVKVLVVDDSGFFRRRVTEILSSDPNIVVVGTATNGKEAIEQALALKPDVITMDYEMPMMDGITAVRHIMQRIPTPVLMFSSLTHEGARVTLDALDAGAVDFLPKNFEDISRNPQKVKQLLCEKINSISRSNRRSSGFGSASAAPAAPAPSTLSSRASAPAPAPARAVPSRTATPAAAPAAPTSHAPAHPTTSGTAKRKAYKLVAIGTSTGGPVALQRVLTQLPANFPAPLVLIQHMPAAFTKAFAERLDKLCKISVKEAEDGDVLRPGLALLAPGGKQMMVDGRGTVKILPGDERLNYKPCVDITFGSAAKSYGDKVLSVVLTGMGADGREGARLLKQAGSTVWAQDEASCVIYGMPMAIVKAELADAIYSLDDIGRHLVEACL
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 3.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_KORVE
Sequence: MAQIKADEITKLIRSQIENYETKIAVDEVGTVMSIGDGIARVYGIDKVMAGELLAFPHGVAGIAMNLDEDQVGAVLLGEYTAIKEGDEVKRTKRIMSVPVGEAMIGRVVNALGQPIDDKGPIVTDKFNPVERIAPGVIDRQPVREPMATGLKAIDAMIPVGRGQRELIIGDRQTGKTAVALDTIINSKGKNLICVYVAIGQKRSSVAQVVKMLEDNGAMEYSIVVVASASDPAPMQYIAPYSGTAIAEYFRDSGRHALCIYDDLSKQAAAYREISLLLRRPPGREAYPGDVFYLHSRLLERSSKLSDKLGGGSITALPIIETQAGDVSAYIPTNVISITDGQIYLETDLFNSGVRPAVNVGLSVSRVGFSAAIKAMKQVGASLKLELAQYRELAAFSQFGSDLDKATQAQLNRGQRLVEILKQDQFQPLPFSKQITIIFAGTNGLLDDLEVKDVRPFEKALYEYVESANPQLFRTIEEKKALDDAIKADMTKTIKEAKERFLSDRKAAKAGA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FABZ_BACC7
Sequence: MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEIACEAEITFAIGDKKE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_ECOBW
Sequence: MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFFTGKQRDVATGGRVDRFNKRFNIPGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: CARA_HALH5
Sequence: MKRQLILEDGSVFVGKGFGSDREMSGEVVFNTGMTGYQEMLSDPSYCGQIVTLTYPLIGNYGINRDDFESMNPAIHGLIVKEACDIPSNWRSEESLDSLLKAKQIPGLSGIDTRKLTRLIRMHGTLKGQLCPLDVDVEQIVQELKATPTPTDQVSRVSTRDPYHVPGPGKRVVLVDYGMKHNILQELIRRNCEVFVVPYHTSAEEVLRLGPDGVLLSNGPGNPEDVSEGVEMIRNLLGKVPLFGICLGHQLFALACGAKTEKLRFGHRGSNHPVRERSTGLIEITAQNHGYTVTEGSLVNTDLIVTHEAVNDGTIEGLAHKVHPAFSVQYHPEASPGPEDSNVLFDRFIKLMESNKHRALTV
What are the official names of this protein?
Carbamoyl-phosphate synthase pyrimidine-specific small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: RL30_IDILO
Sequence: MAKKTIKVTQTRSSIGRLPKHKATLRGLGLRRIGHTVELEDTAAVRGMVNRVNYMIKVEG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: APBE_CHLTR
Sequence: MGKFFASYLLILAPFFLQSCSAPSRTTLEGVRMTIPYRIVFGEALSPDAFQQAQKEIDRVFDHIDQTFNNWNPLSEISRINRTTKQTPIPLSPALFAFLCEIDHFHAFSDGRFDPTLGALKSLWLLHLKSHTIPSQELQHLYKHSSGWHLISLDKTQQTLRKLSPLVQLDLCGTVKGFAVDLLGTACAQFCQNYYVEWGGEIKTKGKHPSGRSWAVASSATPEILHLHDHAIATSGSQYQRWHVDNKTYTHILDPLTGTPLEDSSHPILAVSVINESCAFADAMATALTTFSSKQEALDWANKKHLCAYITDKNVS
What is the function of this protein?
Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein such as NqrB and NqrC, two subunits of the NQR complex.
What are the official names of this protein?
FAD:protein FMN transferase, Flavin transferase.
What is the protein family that this protein belongs to?
Belongs to the ApbE family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor; Periplasmic side.
Protein: YQGF_CLOBL
Sequence: MRILGLDIGDRTIGIAISDPLGFTAQGITTIRRKSEAYDLEEIKKICDKYEVDTIVSGLPKNMNGTLGPQSEKVLEFCDLIKEHLNIEIKMWDERLTTVAATRAMLEADLSRSKRKKIVDKVAATYILQGYLDSLSK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: N24_MEDTR
Sequence: MSTINIESLDQDTKDEPKEQTQEDNNEVLKVLEEKINMMDPKNTSGDTEVVITNFLKSKKEVKWYVALLVIRVFAFVFCLIAFSVLGASEQRVLVSENLTNWYSSGFTIQTPYEFHWYKWDEFRYSFAANVIGFVYSGLQICHLVMYLITKKHTINPKLQGYFNVAIDQTLAYILMSASSSAATAAHLLKDYWLEHGADTFIEMANASVSMSFLAFGAFALASLVSGIILCRFT
What are the official names of this protein?
CASP-like protein N24, CASP-like protein 4A1, MtCASPL4A1, Nodulin 24, MtN24.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMM_ALTMD
Sequence: MSDTSILAYCRPGYENDTANELTSRYGEAGFYGYPVSKKNSGFAHYHLYDAAQLEQTVTQFAVHDSIFPRQLVAVFAAINDVEKEDRVGQVLDALKEVEKPFSIFGAVDVEYPDTEEGKTLAKFCRKFTVPLRQALRKAGWLTAKENLGKPKLHIFFASFEICYIGFTLPSHASRDHLGICRLKFPSDSPSRSTLKLEDALVNMLSNKQQSKVLRSGGRAVDLGACPGGWTYQLVKRGMYVEAIDNGLIADSLMSTGLVEHHAADGFTYRPQFGRVDLLVCDMIEQPDRVAKLMGDWLVKHWATHAIFNIKLPMKRRYETVVEAMTSLNSRLDALDDAFAVKVRHLYHDRDEVTVTIVRTSKDEV
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLRN1_MOUSE
Sequence: MPSQQKKIIFCMAGVLSFLCALGVVTAVGTPLWVKATILCKTGALLVNASGKELDKFMGEMQYGLFHGEGVRQCGLGARPFRFSFFPDLVQAIPVSIHINIILFSMILVVLTMVGTAFFMYNAFGKPFETLHGPLGLYLVSFISGSCGCLVMILFASEVKVHRLSEKIANFKEGTYAYRTQNENYTTSFWVVFICFFVHFLNGLLIRLAGFQFPFTKSKETETTNVASDLMY
What is the function of this protein?
May have a role in the excitatory ribbon synapse junctions between hair cells and cochlear ganglion cells and presumably also in analogous synapses within the retina.
What are the official names of this protein?
Clarin-1, Usher syndrome type-3 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the clarin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYB_CANLF
Sequence: MTNIRKTHPLAKIVNNSFIDLPAPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYVFMETWNIGIVLLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPSGITSDSDKIPFHPYYTIKDILGALLLLLILMSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILAFIPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQVASILYFTILLILMPTVSVIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NADK_THESQ
Sequence: MKIAILYREEREKEGKFLKEKISKEHEVIEFGKANAPGRVTADLIVVVGGDGTVLKAAKKAADGTPMVGFKAGRLGFLTSYTLDEIDRFLEDLRNWNFREETRWFIQIESELGNHLALNDVTLERDLSGKMVEIEVEVEHHSSMWFFADGVVISTPTGSTAYSLSIGGPIIFPECEVLEISPIAPQFFLTRSVVIPSNFKVVVESQRDINMLVDGVLTGKTKRIEVKKSRRYVRILRPPEYDYVTVIRDKLGYGRRIE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_PSEPK
Sequence: MDLLFLGTSAGVPTKARNVSATAVIEASGSHWYLVDCGEGTQHRLLHTPLSIRDLRAIFITHVHGDHCFGLPGLLASAGMSGRTQPLEVILPAVLHDWVRQGLVASDTFLPFELRLLPVEELIAWRSETLQVTTVQLSHRVPSVGFVFTEINPEPRLDIQRLDAEGITRGPLWGELAKGLTVTYDGQLLNGNDYLRPSRPPRRVIVCGDNDKPELLAAVARGADVLVHEATFTQAVVERTGGTFGHSTAAEVARFAEAAGVRNLVLTHFSARYQNDPRRSPHIDNVRDEALAHYSGQLTLAQDLQRYHLGRNGLLEASA
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: GRPE_COXBU
Sequence: MSSKNNPESETKAKNKWEKVMEAEEEQEEGRGDGSQEMEPHREGLEFPSREKLEGQLTRMERKVDEYKTQYLRAQAEMDNLRKRIEREKADIIKFGSKQLITDLLPVADSLIHGLESPASEDPQVKSMRDGMSLTLDLLHNTLAKHGVQVINPNPGDPFDPALHEAMSVQAVPDAKPDTIIQVLQKGYQLNGRVLRAARVIVAG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_CYTH3
Sequence: MARVCQITGKKTRTGNNVSHANNKTKRTFAPNIQKKRFFLSEENRWVTLKLSTKAIKTISSKGLSAVLEKATAAGYLKKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ATPA_DESVH
Sequence: MQIKAEEISKIIEEQIQSYEQRVEMSETGTVLYVGDGIARVHGVQNAMAMELLEFPGGLMGMVLNLEEDNVGVALLGDDTQIKEGDPVKRTGKIFSVPVGDAVMGRVLNPLGQPIDGLGPLDAKEFRPVELKAPGIIARKSVHEPMPTGIKAIDAMTPIGRGQRELVIGDRQTGKTAVCIDAILAQKNTDIHCFYVAIGQKKATVALVADTLRKYGAMEYTTIISATASEPAPLQFISAYSGCTMAEFYRNNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKVNDSLGAGSLTALPIIETQAGDVSAYIPTNVISITDGQVYLEPNLFNAGIRPAINVGLSVSRVGGAAQIKAMKQVAGTMRLDLAQYRELAAFAQFGSDLDKATKAKLDRGARLVELLKQPQYEPMPTEEQVASMYAATRGLMDDVAVADIRKFETAMLDYLRSGKADILNDIKTKKALDQDIENRLKAAIAEFKKGYQA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: OASL1_MOUSE
Sequence: MAVAQELYGFPASKLDSFVAQWLQPTREWKEEVLETVQTVEQFLRQENFREDRGPARDVRVLKVLKVGCFGNGTVLRSTTDVELVVFLSCFHSFQEEAKHHQAVLRLIQKRMYYCQELMDLGLSNLSVTNRVPSSLIFTIQTRETWETITVTVVPAYRALGPSCPSSEVYANLIKANGYPGNFSPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVRDKCPRANLPPLYALELLTVYAWEAGTREDANFRLDEGLATVMELLQDHELLCIYWTKHYTLQHPVIEACVRRQLRGQRPIILDPADPTNNVAEGYRWDIVAQRANQCLKQDCCYDNRDSPVPSWRVKRAPDIQVTVQEWGHSDLTFWVNPYEPIKKLKEKIQLSQGYLGLQRLSFQEPGGERQLIRSHCTLAYYGIFCDTHICLLDTISPEIQVFVKNPDGRSHAYAIHPLDYVLNLKQQIEDRQGLRCQEQRLEFQGHILEDWFDFKSYGIQDSVTVILSKTTEGAAPFVPS
What is the function of this protein?
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA.  Displays antiviral activity via an alternative antiviral pathway independent of RNase L.
What are the official names of this protein?
2'-5'-oligoadenylate synthase-like protein 1, 2',5'-oligoadenylate synthetase-like 9.
What is the protein family that this protein belongs to?
Belongs to the 2-5A synthase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm.
Protein: CLPP_CHRSD
Sequence: MGNEFDISNAGGLVPMVVEQNARGERAYDIYSRLLKERVIFLIGPVEDYMANLVVAQMLFLESENPDKDIHLYINSPGGSVTAGMSIYDTMQFIKPDVSTVCVGQAASMGALLLAGGAAGKRYCLPHSRMMIHQPLGGYQGQAADIEIHTKEILNIRQQLNEILAKHTGQDAETVARDTDRDNFMNGTQAVEYGLIDAMLDKRPVS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMR1A_HUMAN
Sequence: MPQLYIYIRLLGAYLFIISRVQGQNLDSMLHGTGMKSDSDQKKSENGVTLAPEDTLPFLKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKAQLRRTIECCRTNLCNQYLQPTLPPVVIGPFFDGSIRWLVLLISMAVCIIAMIIFSSCFCYKHYCKSISSRRRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTLAKMVESQDVKI
What is the function of this protein?
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.  Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.  Receptor for BMP2, BMP4, GDF5 and GDF6.  Positively regulates chondrocyte differentiation through GDF5 interaction.  Mediates induction of adipogenesis by GDF6.
What are the official names of this protein?
Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, Serine/threonine-protein kinase receptor R5, SKR5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell surface.
Protein: DAPE_BORPA
Sequence: MTASAVLDLVKDLIARPSVTPDDVDCQMLLAQRLERIGFQCETIARGGVTNLWARRGAGAPLTVFAGHTDVVPPGPRDKWDSDPFVPTERDGFLYGRGAADMKSSIAAFVVAAEEFVAAHPEHPGSIALLITSDEEGPAVDGTVIVCDELRQRGEQLDYCIVGEPTSTEALGDVCKNGRRGSLSGRLLVKGVQGHVAYPHLARNPVHQLAPALTELVAIEWDQGNEYFPPTTFQVSNLHAGTGATNVVPGEAVALFNFRFSTASTPDQLKARVHEVLDRHGLEYQLDWELGGEPFLTPRGSLTDALVSAIQAETGLQAELSTTGGTSDGRFIARICPQVIEFGPCNATIHKVNERIELSSLAPLKNIYRRTLENLLLAD
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: YHBE_BACSU
Sequence: MDVVEKLVINGSGSSKGGTFQSVEINGSGTVAGDVECDTFSFNGNGKADGSVKAKAVTISGSGKIHGDVEAESIRMNGTGFIQGEVSAKQLKIAGSSTFGGTVKADGIDISGKAVMEADCETETFQSEGKCKISGLLNADQVIIKLSAGESYAREIGCRHLQVTCRKGMLTLLRLMPQPVLTAELIEGDVIELTNTKAKTVRGNKVIIGPDCQIETVEYSGDYTCDPSASVETSTKL
What are the official names of this protein?
Uncharacterized protein YhbE, ORF1.
Protein: FBK6_ARATH
Sequence: MKRLPLHLLDEILFNLDPKSLGKMRCTNKSINTHISDDPNFKFEYFSRIGSSLLHISKVGSKFLCFYPYAISRLFKNMTPLKNLCNILGSCSGLVLLSINGILCVANPLTKKFRFLHYSIWGNETWIGFAVDQIDRATQRFKIVFISEQLEVSNPYETTYQFRINTGESWSLSKTTITCRASNLKKGKNSKPVYVNGDLHWLRKDGSIVAFNPETEKARLIQSQFNRKPGKLLLCTGDNRLTLISATDAVISVYALETDGQWILVRWIKNEVVHQSLPLLYWNVQAYDGKCLLVRMMSLVGSVIHRYDLRANKWRVLGSIPTWCDADRDFFLFKPSWSSVIGLLDQEHVHVLMPMPMPMPMPMPMPMHMHMHMHMPMPMAMPMPMPIAMAMPMPMPMPMPMPMTKTETETVTRSEVISSVMAIMGLVNRTLSFIN
What are the official names of this protein?
Putative F-box/kelch-repeat protein At1g20790.
Protein: CRZ1_YEAST
Sequence: MSFSNGNMASYMTSSNGEEQSINNKNDIDDNSAYRRNNFRNSSNSGSHTFQLSDLDLDVDMRMDSANSSEKISKNLSSGIPDSFDSNVNSLLSPSSGSYSADLNYQSLYKPDLPQQQLQQQQLQQQQQQQQQQQQQQQKQTPTLKVEQSDTFQWDDILTPADNQHRPSLTNQFLSPRSNYDGTTRSSGIDSNYSDTESNYHTPYLYPQDLVSSPAMSHLTANNDDFDDLLSVASMNSNYLLPVNSHGYKHISNLDELDDLLSLTYSDNNLLSASNNSDFNNSNNGIINTADTQNSTIAINKSKVGTNQKMLLTIPTSSTPSPSTHAAPVTPIISIQEFNEGHFPVKNEDDGTLQLKVRDNESYSATNNNNLLRPDDNDYNNEALSDIDRSFEDIINGRKLKLKKSRRRSSQTSNNSFTSRRSSRSRSISPDEKAKSISANREKLLEMADLLPSSENDNNRERYDNDSKTSYNTINSSNFNEDNNNNNLLTSKPKIESGIVNIKNELDDTSKDLGILLDIDSLGQFEQKVGFKNDDNHENNDNGTFSVKKNDNLEKLDSVTNNRKNPANFACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTESGRRCITPLYEEARQEKSGQES
What is the function of this protein?
Involved in the regulation of calcium ion homeostasis.  Binds to the calcineurin-dependent response element.  Transcriptionally regulates PMC1, PMR1, PMR2A and FKS2.
What are the official names of this protein?
Transcriptional regulator CRZ1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PG164_MONPV
Sequence: MLYIEQSEMMLVPLITVTVVAGTILVCYILYICRKKIRTVYNDNKIIMTKLKKIKSPNSSKSSKSTDSESDWEDHCSAMEQNNDVDNISRNEILNDDSFAGSLIWDNESNIMAPSTEHIYDSVAGSTLLINNDRNEQTIYQNTTVVINDTETVEILNEDTKQIPSYSSNPFVNYNKTSICSKSNPFIAELNNKFSDNNPFRRAHSDDYLNKQQDHEYDDIESSVVSLV
What is the function of this protein?
Involved in the intracellular transport and egress of virions to the host cell surface with help of protein OPG056.  Participates also in the formation of actin tails at the plasma membrane to allow efficient actin-based motility and thus cell to cell transmission of viral particles.  Recruits host intersectin-1/ITSN1 and activates host CDC42 to drive ARP2/3-mediated actin polymerization.
What are the official names of this protein?
Protein OPG164.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG164 protein family.
Protein: KV224_HUMAN
Sequence: MRLLAQLLGLLMLWVPGSSGDIVMTQTPLSSPVTLGQPASISCRSSQSLVHSDGNTYLSWLQQRPGQPPRLLIYKISNRFSGVPDRFSGSGAGTDFTLKISRVEAEDVGVYYCMQATQFP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 2-24.
What are the subcellular locations of this protein?
Secreted. Cell membrane.