PharMolix/UniProtQA huggingface dataset:
Protein: BXLB_ASPFC
Sequence: MAHITSWHYGNAIALLVSLAPGALSLNTFPDCSSGPLSKLAVCDTSLDVTTRAQSLVNAMTFEEKVNNTQYNSPGVPRLGLPAYNWWSEALHGVAGSPGVEFADSGPFSYATSFPQPILLGATFDDDLIKQVATVVSTEGRAFGNAGRSGLDFWTPNINPFRDARWGRGQETPGEDPLHVSRYVYHLVDGLQNGIGPANPKVVATCKHFAAYDLEDWNGVVRHSFNAEVSTQDLSEFYLPPFKSCARDARVDAVMCSYNALNGVPACADSYLLQTILREHWKWDEPGRWITSDCGAIDDIYNGHNFTTTPAEAAATALNAGTDLDCGTVFPKYLGQAADEGLYSNQTLDRALVRLYSSLVKLGYFDPAEDQPYRSIGWTDVDTPAAEALAHKAAGEGIVLLKNDKTLPLKAKGTLALIGPYANATKQMQGNYEGPAKYIRTLLWAATQAGYDVKYAAGTAINTNSTAGFDAALSAAKQADVVVYAGGIDNTIEAEGRDRTTIAWPGNQVNLIDQLSKIGKPLVVVQFGGGQVDDSSLLSNPRVNALLWAGYPSQEGGSAIFDILTGKTAPAGRLPVTQYPADYVNQVPMTDMALRPGSNTPGRTYRWYDKAVLPFGFGLHYTTFKISWPRRALGPYNTAALVSRSPKNVPIDRAAFDTFHIQVTNTGKTTSDYVALLFLKTTDAGPKPYPLKTLVGYTRAKQIKPGEKRSVDIEVSLGSLARTAENGDLVLYPGRYTLEVDVGESQYPTASFTVTGKETILDSFPQPPKTR
What is the function of this protein?
Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable exo-1,4-beta-xylosidase bxlB, 1,4-beta-D-xylan xylohydrolase bxlB, Beta-xylosidase bxlB, Xylobiase bxlB.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: WBP2L_MOUSE
Sequence: MAVNQNHTVDRRWAAIPHGESLLKKCSEVDLSFPQSPPGSNLFSGTKRGALFLTSYRVIFVTSRADNDPMFSFTMPFHLMNNCTVEQPIFGANYIKGTIQAAPDGGWEGSATFKIVFRKGGAIDFAQLMAKAASAAAQGVPLRVASFWMGPLGIYVITGDRNMYAPQAYQVAYGAPPAGYGASPVGYGVPSAGYGAPPAGYGAPPVGYVAPSPGYDVLPPGYGAVRYGSPPPLYVATPMGYGVPPPGYGPPPVRYGSPPPGYEAPTMEYGAQPPRYGTTPMGSGSPPPRYEAPPMGYGTPPSGRESIPPGSRATSVAQEAPPAGSEAGHPMSVAVQNPEFQASFPSTSSSQVHSPRSKM
What is the function of this protein?
May play a role in meiotic resumption and pronuclear formation, mediated by a WW domain-signaling pathway during fertilization.
What are the official names of this protein?
Postacrosomal sheath WW domain-binding protein, WW domain-binding protein 2-like.
Protein: MYHV2_BOMMX
Sequence: MNFKYIVAVSFLITSGYARSVKNDEQSLSQRDVLEEESLREIRGIGGALLSAGKAALKGLAKGFAEHFGKRTAEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANLFTKKEKRILGPVLSLVGSALGGLIKKIG
What is the function of this protein?
Maximin-Hv shows antimicrobial activity against bacteria and against the fungus C. albicans.  Shows strong hemolytic activity (By similarity).
What are the official names of this protein?
Maximins y/Hv type 2.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_BACLD
Sequence: MRYDGRKNNELRPVTMDLDFITHPEGSVLITVGGTKVICNASVEDRVPPFLRGEGKGWITAEYSMLPRATNQRTIRESSKGKISGRTMEIQRLIGRALRAVVDLEKLGERTIWIDCDVIQADGGTRTASITGAFTAMALAVGRLVEKGALKEMPITDFLAATSVGIDKEKGLILDLNYQEDSAAEVDMNVVMTGEGRFVELQGTGEEATFSRSELDGLLELAEKGIAELLEKQKEVLGDVALSIQQ
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: YCF2_PINTH
Sequence: MKKRRRPWIIKLEEIQSYQFLCNPWTKSNLIRLLIQILSRRERLIKLFDPRILSTLLLRDLRKSNPYFLVKGIVVLTLSILIYRFNHQSSMIDRKNFYSIKLFPIHNFMELGNETPEEYLKPFTQNWLRFPHLLLSFQLKRYYNRDFDPISLNSGYGKNTNKKDEIISKNQGPSETHSENDEKDINLKIDSTLNSTENEYWKPEKYLCEDPFTRNKTEIEQRRKRSILWDLSFIEREQTKIESDLSSKCLSKDYPISWAKELFTEDQRYTEENSFPLERKRFIENFTKSIRYSFFYILPIDEPCMGGPSATKKPIEDFNLSKRLFKIKKNVFSQDLRDSKSYSLMNRIVDLWKIKTYFEIENPSLNCAMRSFTLPWNLFSAFCDQSKGKYILHKNCLEMTDQFTLSITKPSQVHDKISFFIYYNKNGSLRSDRIFNHREKWKNQSLWVLLNIIDKADDYLDQIIDKQLSQIDSKNCLEIGTPFNNYRTEALGWYESIKYNIDNRYSKNLLNRFYFINRLSRNLKDQIRTNFIENENLNNVTKDTIDRHSSSWKKIKREWFNHSIIRIDKHINRNLNVYKWSNQTEYFMKYLKQVFSKKNYFKIVFDPIELCTNTNRDSIGWSVFLSLSESTVKILNSKFDIISNLNSKFDILISFFDFAFHGLQSMNYRLLNQLLDPIGTLIVRLKKFKTFLLYDHNLSQRSKLLIDEGTIAPFVTNKIPINPLIIDFFDNENNRMESFDNTYFSTISNDRDNWLNPVKLSDQSSLIASFHGANTLQFFDYLHHTRPNYRNRLPSDMKRFYIKRNNFTYGQLFNLLIIHNNLSSLPIGEIGPVHSEKETISFIKSQVSNILLPKYLKRKRSGDQTFVLIYDLYRSFNLLTRLNPFVREKRYLSSIEEISTTPLTKEQIVNFEKNFCQPFFKRSDSEENNFDQCFKRGFSSNVGLIQTRSYQDDLLSEMFSNKNEEIFPRIQDWFVTECLKNKIVNEDIDGRSTLSNSSKEEQNIYRISQIDSIFSKWDLFKTYMPWFFTSAWCKYIENMLLDTLSEILLHGSNPFVSILQNIKHNILLKRNILWELSHPLWEPIQCKLRTNLINKFFFPSNNFKDFFPYCKDFLIEETSDREKSSVPFIWAHMRLLNARGYKYGILIPFFVLGYSILQYFKVISFTFINIKRYFELIKYLKHPSYVIELQKMINPPVPNSFLYYTIDRDRSSSLPQIINSFFSMNMKRKRKTKRKTKNRNIKLLITIIRELNGLCSSMDISEKEMNLLVQFLMTEKALFKFESIFTYSPNLFKNEFGDQIIRQPGLIHLRYLAYTYQKGLINYGFNPFCLAERWVFLAFCQKITSSQILCQTNPTFHGKPFSLHSGSLLSKGILLIGPMGTGRSYLVKSLAADSYVPLIRISLKKLWYGEYLDYPLERIPTEFDPFVKDKMEDFHITLELAKRMSPCIIWIPNIHELNLNDATNYLFGFGFTDLFLSVLMNNLFRFRDGEKDSMRNILVIASTHIPQRVDPALIAPNRLDRSINIRMLVIPQRQREFPILLCSKGLYSVKFPDEFGSITIDYAVRDLAALADEALILSITRNKSVIDTNTIRSAIYRQIFHLQSMDNQVGSSQNDERIIYKVGKAFIQNTLRRNSPMNPLSTKKELWKKRFCYLSEWYLEPSIAETTMKELTILPHILGCLAGSAARDSWSISERNRENWIPFDKLAEHDLDIASSLLESILVEFPFSRLGICRGKSDKDQITFAPQLKMRDNLDLIRFMKEYELKFTPGAKQRDMDEELIKNVVWTPRIWRLSFLRSNRFDHIKTPNSLGSSYQFGSLRKRQMDRSLFPIQYPKQYKYSKKPLFFIGRRFLWDSFLFQEQRPVFSRREFFANEELLKRLYITYGARRLIAQPDFFPKKSIQSFFRRYDSKSTINSVLVMNWWKPLSLRHRHIEHFKRIQAIGIQLERMQPYFPIYSYNRWLTENSRERVDRFQSLIHRQRWLGTNRLLSNESFLYNTLFESYQYLSNLFLSNRMLLDQITKTLLENKWLFPNEIEHSIHTTGLRFDISWENME
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: HISX_HAEI8
Sequence: MQTIIWNHLSETEKRKVIMRPVQQNGENIQQAVNAIRENVAYNGDRALFELCEKFDGVKLDKLIVSADEIQAASSRISVKLRNAIEQAKTNIEAFHKAQQNQEIDLEIQEGVRCQVVTRPISCVGLYIPGGSAPLFSTVLMLAIPAKIAGCKKIVLCSPPPISDEILYTAHLCGVETIYAIGGAQAVFAMAQGTESVAKVDKIFGPGNAFVTEAKRQVAQNSTAIDMPAGPSEVLVIADESADPEFVASDLLSQAEHGADSQVILVATCETLAKETALAIERQLALLPRAETARKALNHSRIFIAESLEQAVEISNEYAPEHLIVQTKNARKLLPYLDNAGSIFLGAYSPESMGDYASGTNHVLPTYGYTKTYSSLGLADFSKRMTVQELTPKGFKNLAETVEVMAEAEQLAAHKMAVSVRLAKLNI
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: TRPB_BACAH
Sequence: MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLNTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEELEGKLPEAVVACIGGGSNAMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RPOZ_RHIE6
Sequence: MARVTVEDCIDKVENRFELVLLASHRARLISQGASITIDRDNDKNPVVALREIADETLSPDDLKEDLIHSLQKHVEVDEPEPDPASMIAAGGVAAADSEEQDDLPETITFDQMSEEELLAGIEGLVPPEKSDDY
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ACPS_CAMLR
Sequence: MIGCDIVACSRIESIYNRHNTLFLDKFLSKQEQAYIKNTNTIAGFWAIKEAASKALGVGISKECSFFDIIIFKDNKNAPHIKFSTKVMKEFDIKSASVSVAHDGGFAIAVVAIEKN
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_CITSI
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ASTB_TALWO
Sequence: MIDSLSFTTMPVVLLVGLVLYQLLAFTYRLFFSPLAKFPGQKIAGMTHWYEFYHDVIRRGQYTFHIRDMHKKYGPILRINPYELHISDPSFYNEIYAVQNRRRDRWEWSTRPGGFGGSVGGTNPHELHRRRRAALNPFFSRANIRKLQHEIDQKAVQLVERLEKETDRVIKVNHAFAALTNDIVMQYSFGRDDNRAAHKDRAARALPMEMLSKISSVVAMFWQEKQSITEEVRQILNGTNKAYKERPNRTIYHGILESKLPPEEKELNRLAEEAQITIGAGTLATAWVMSVGMYHLLAPGSVSMLKTLREELQRAIPDPSEPIDLAALEKLPYLTGVVKECLRLGNGTTTRLQRIAPDETLIYTDPNTGKVWDIPPGTPVSLSSLHIHHDETIFADPESFRPERWIENPDLERYLLTFSKGSRQCLGIHLAYAEMYIVLARVFRLYGRKEEGPSKGPSDKLGNLELFETELRDTLCVADLVVPAVWEGSQGIRIKVTE
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the asperterpenoids, sesterterpenes that exhibit anti-tuberculosis activity (PubMed:30548032).  The first step of the pathway is performed by the sesterterpene synthase astC that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylfarnesyl diphosphate (GFPP) and further converting GFPP into preasperterpenoid A, respectively (PubMed:30548032).  The cytochrome P450 monooxygenase astB then dually oxidizes preasperterpenoid A to produce asperterpenoid A along with a minor product, asperterpenoid B (PubMed:30548032).  Finally, the cytochrome P450 monooxygenase astA converts asperterpenoid A into asperterpenoid C (PubMed:30548032).
What are the official names of this protein?
Cytochrome P450 monooxygenase astB, Asperterpenoid biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: UBIC_NITMU
Sequence: MNAAQLSDWHPAPSSISPRARGWLQNRGSLTQLIQRRCCSEFSVKPVFQSLATVCDDELAVMNLRRDELALVREVYLYCGETPVVFAHSVVARKHLRGAWRSLIGLGNKSLGTVLFTNPVVKRTPLRFKKLTAAHPLFSRACRKLRVQPGNLWARRSLFTLHGQSILVTEVFLPSILELA
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_GEOTN
Sequence: MSKKVTETVEQLVTPILNEMGLELVDIEYVKEGKNWFLRVFIDSDDGVDIEQCGVVSEKLSEKLDEVDPIPHNYFLEVSSPGAERPLKNEKDFVKAIGKHVYIKTYEPIAGEKQFEGELTAFDGTTVTLSVKDRGRQKTVAIPYEKVASARLAVIFF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YM79_YEAST
Sequence: MVLCKLLTPYFLLSILSVGVFTATAAPSPSIQMTENTNQDHHEHAKRGGTCAFPNYDGMVAVQKGGSNGGWAMSPDQECSYGSWCPYACKPGQLMGQWDPSATTYSYPKCQNGGLYCDSNGNLQKPNSDKDYCYDGKGTVIAKNNANSGDVAFCQTVLPGNEAMLIPTLVGSGSKQTLAVPGTDYWASSASHYYVNAPGVSVEDACQWGSSANPQGNWAPFVAGSNMDDNQNTFVKIGWNPVYLESSCPFKNVKPSFGIRITCDDESQCEGLPCSIDPSSNGVNEVTSSGGGSSGAGGGNFCVVTARNGAKANIEVFDVGSGSSSKGKRELNPLDVITTTVTETKYKTVTVTAKT
What are the official names of this protein?
Uncharacterized protein YMR244W.
What is the protein family that this protein belongs to?
Belongs to the SUN family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KCTD9_HUMAN
Sequence: MRRVTLFLNGSPKNGKVVAVYGTLSDLLSVASSKLGIKATSVYNGKGGLIDDIALIRDDDVLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNSQPPEDHSPISRKEFVRFLLATPTKSELRCQGLNFSGADLSRLDLRYINFKMANLSRCNLAHANLCCANLERADLSGSVLDCANLQGVKMLCSNAEGASLKLCNFEDPSGLKANLEGANLKGVDMEGSQMTGINLRVATLKNAKLKNCNLRGATLAGTDLENCDLSGCDLQEANLRGSNVKGAIFEEMLTPLHMSQSVR
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of target proteins, leading to their degradation by the proteasome.
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD9.
Protein: RL28_ALKEH
Sequence: MSKVCQVTGKRPTTGNNVSHANNKTKRRFLPNLHHHRFWVESEQRFVRLRVSSKGMRIIDRKGIDQVLSDLRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RECF_BACC2
Sequence: MFISEIQLKNYRNYEKLELSFEDKVNVIIGENAQGKTNLMEAIYVLAMAKSHRTSNDRELIRWDEEFGQIKGKLQKRNSSLSLELNISKKGKKAKLNQLEQQKLSQYIGVMNVVMFAPEDLNLVKGSPQVRRRFLDMELGQIAPIYLYELSQYQKVLTQRNHLLKKMQGNSKNEETMLDVFTLQLIEHGAKILQKRFEFLHLLQEWAAPIHRGISRGLEELEIVYKPSVDVSESMDLSKIKEVYYESFQSVKQREIFRGTTLIGPHRDDLQFFVNSKNVQVFGSQGQQRTTALSLKLAEIELIYSEVKEYPILLLDDVLSELDDYRQSHLLNTIQGKVQTFVTTTSVDGIEHETLKDAKTIHVTNGTVDCEIDRA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL308_MIMIV
Sequence: MYTTSKNNTNYSKNLYLSSNKTKQEIFRYLNSTGINLHTKFEIISNESDLNYIRDNEYIICPKYSGVRSWVIFFKNDNDVYYAVSFPKYGRFKKEEFSIFPIDVSVTKQLYYGTIMEGIYFKMDNKKCLIIDEVYQFAGEHMLLKTKRDRLEFLQEKFKTTVVMTPNYGLYVSAYFYPDKENIKELYNNIKNNMSIQEIIFYPNIYGKKVYSYMITETDLVDNIIKLAQLYLEKTASPDVYNLYRINSDKKIDIAYIPDIETSRKCKQWFKDSKEKKLLVRCKMDMNIKKWIPQEIIENNEILLESENESENESENESEYDE
What are the official names of this protein?
Uncharacterized protein L308.
Protein: ADE_PSEPG
Sequence: MYDWLNALPKAELHLHLEGSLEPELLFALAERNKIALPWNDVETLRGAYAFNNLQEFLDLYYQGADVLRTEQDFYDLTWAYLQRCKAQNVVHTEPFFDPQTHTDRGIAFEVVLNGISQALKDGREQLGISSGLILSFLRHLSEDEAHKTLDQALPFRDAFIAVGLDSSEMGHPPRKFQRVFDRARSEGFVAVAHAGEEGPPEYIWEALDLLKIKRIDHGVRAIEDERLMQRIIEEQIPLTVCPLSNTKLCVFDHMSQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALHTHLGMTEDQARRLAQNSLDARLI
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: THIG_RHORT
Sequence: MARTTYKETALDEGDQLEIVHFIGGGDRSDPQPADDPFTVAGRVFSSRLLVGTGKYRDFEETARAIEASGAEIVTVAVRRVNVSDPSQPMLVDYVDPAKYTYLPNTAGCFTADEAVRTLRLAREAGGWSLVKLEVLGDQRTLYPNMAETFLAAEALIRDGFEVMVYCADDPIAAKRLEDMGCVAIMPLGSLIGSGLGIINPYTIRLIKESVSVPVLVDAGVGTASDAAVAMELGCDGVLMNTAIAQAKDPVRMARAMRLAIEAGRLSYQAGRMPRKLYADPSSPLAGLI
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIM33_HUMAN
Sequence: MHQAGHYSWPSPAVNSSSEQEPQRQLPEVLSGTWEQPRVDGLPVVTVIVAVFVLLAVCIIVAVHFGPRLHQGHATLPTEPPTPKPDGGIYLIHWRVLGPQDSPEEAPPGPLVPGSCPAPDGPRPSIDEVTCL
What are the official names of this protein?
Small integral membrane protein 33.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NUOB_BRUA1
Sequence: MGLTGTNTTLVAPQPKGILDPRTGKTVGSDDAFFNDLNGELSDKGFIVTSADALITWARTGSLMWMTFGLACCAVEMMHISMPRYDAERFGIAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRVVPVDIYVPGCPPTAEALLYGILLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HGPRT_STRPN
Sequence: MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKGSIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDIIDTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDYKENYRNLPYIGVLKEEVYSN
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_PROMA
Sequence: MIKLRLKRFGKKREASFRLVACNSTSRRDGRPLQELGFYNPRTKETRLDTEALRLRLSQGAQPTDAVRSLLEKGGLLEKTIRPAELIGKSKQEELRKSEAKTSAKNKKANEEKANEEKVEESETLEASSEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: EX7L_HAEI8
Sequence: MSDNIYSVSQLNSAARQMLEGNFSQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCAMFRMKNLRVAFRPQNGMQVLVRANVSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKLAAEGLFAQNLKKTLPHFSKAVGIITSSTGAALQDILHILARRDPSLKVVIYPTAVQGKEATAEIVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETDVTIADFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLALRLQNQHPQNQLRAQQAKNEQLTHRLQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRYQQGLEQLKVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKVLARGYSIAENPQGKAIVSVKDVNQGDFITTQVADGKIVSKVL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PILA1_THET2
Sequence: MTRRGLTLLELLLVLGILGVLLGLALPLLSPNRLALDQAARSLATQVTRARLEAIRRNAFVGLQVFTEGAGGYLLFVDQNANRRYDPGEEFGATHFGQGNWARVRLDPEKSALGNMPLLFDPRGIPAKPITATLVLTSGGATRKVVISQQGRARLE
What is the function of this protein?
Plays an essential role in natural DNA transformation but is not required for pilus biogenesis.
What are the official names of this protein?
Pilin-like protein PilA1.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Cell outer membrane; Single-pass membrane protein. Periplasm. Note=The single N-terminal transmembrane is initially involved in the correct localization to the inner membrane. Once the leader sequence cleaved, this region plays a role in multimerization and protein-protein interactions in the periplasm and the outer membrane.
Protein: COBQ_PSEPW
Sequence: MTTLMVQGTTSDAGKSTLVTALCRWLLRQGVAVVPFKPQNMALNSAVTADGGEIGRAQAVQAQACRLAPHTDMNPVLLKPNSDTGAQVIIHGRAVTSMNAVAYHDYKAIAMQAVLASHQRLSGEYPVVMVEGAGSPAEINLRAGDIANMGFAEAVDCPVILVADINRGGVFAHLVGTLELLSPTEQARVKGFVINRFRGDIALLQPGLDWLEQRTGKPVLGVLPYVTDLHLEAEDGIDVRQGAKDERVLKVIVPVLPRISNHTDFDPLRLHPQVDLQFIGPGQPIPPADLIILPGSKSVRGDLAQLRERGWDTAIARHLRYGGKLIGICGGLQMLGREVHDPLGLEGPAGSSPGLGLLDYATVLEAQKQLRNVAGALSLEQSPVAGYEIHAGVTQGPALQRPAVQLADGRSDGAISADGQILATYLHGLFEGSQSCAALLRWAGLADVQQIDYEALRERDIERLADLVEKHLDTAHLRKLCGVA
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: Y1281_STAAC
Sequence: MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDRQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDKALDKVKDNKTTVKFERDGKTKSVELTPKKTEKKLTKVSSETKYVLGFQPASEHTLFKPIVFGFKSFLIGSTYIFTAVVGMLASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAETTIIAIGAIFMVVIMILVTWNDIRRYFL
What are the official names of this protein?
Putative zinc metalloprotease SACOL1281.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL7_TRIL1
Sequence: MAEITKADVVAFIEKMTVLELAELVKELEEKFGVSAAAPVAVAAAAPAAAAEAAEEKTEFDVILKSAGANKINVIKVVRTLTSLGLKEAKDLVDGAPSPVKTGISKAEAEEAQKQLVEAGAEVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PYRR_THEAQ
Sequence: MRFKAELMNAPEMRRALYRIAHEIVEANKGTEGLALVGIHTRGIPLAHRIARFIAEFEGKEVPVGVLDITLYRDDLTEIGYRPQVRETRIPFDLTGKAIVLVDDVLYTGRTARAALDALIDLGRPRRIYLAVLVDRGHRELPIRADFVGKNVPTSRNEVVKVKVEEVDGEDRVELWEKEGA
What is the function of this protein?
Also displays a uracil phosphoribosyltransferase activity.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.