PharMolix/UniProtQA huggingface dataset:
Protein: PHNX_LYSSC
Sequence: MKIETVILDWAGTAVDFGCFAPVNVFLTIFEDAGVTVTLEEARKPMGMLKIDHIRTMLEMPRINEEWKRVHRQHFTEEDVHLLYNQFESKLMESLATYTDPIQHVTATVQQLREAGIRFGSTTGYTDFMMEVVTKQAATKGYQPDFLVTPTQVSDKGRPYPYMIFRNMEALGAKSTKQVVKVGDTTSDIKEALNAGVWAVGVIIGSSEMGLSEEEFLALTAEEQQQAIEKTKRIFEMTGAHYTIETMKDLPILINTINEELANETNDRN
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: SYC_STRGG
Sequence: MTIRLHDTNARQIRDFVPLTAGCVSIYLCGATVQAAPHIGHIRSGLNFDIMRRWFAYRGYDVTFIRNVTDIDDKIIAKSAEQGRPWWSIGYENERAFNDGYDALGCLPPTYEPRATGHIPEMIEMMRGLIERGHAYEADGNVYFDVRSLPGYLTLSNQELDDLRQPSGEGETGKRDQRDFAMWKATKPGEPSWETPWGRGRPGWHLECSAMAHKYLGSAFDIHGGGIDLIFPHHENEIAQATAYGDEFAKYWVHNGWVTMSGEKMSKSLGNSVLVSEMVKHWRPIVLRYYLGTPHYRSMIEYSEEALREAESAFARIEGFVQRVTEKTGEVVPPADEVPPAFAEAMDEDLGVPQALAIIHTTVRQGNSALAADDKEAAADRLAEVRAMLGVLGLDPLDPHWAGEGDRGEDLHGVVDTLVRLVLDQRQSARARKDWAAADAIRDQLNQSGLVIEDSPAGPRWTLGPR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAMP_GORGO
Sequence: MKTQRDGHSLGWWSLVLLLLGLVMPLAIIAQVLSYKEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDKDNKRFALLGDFFRKAKEKIGKESKRIVQRIKDFLRNLVPRTES
What is the function of this protein?
Exhibits antimicrobial activity against E. coli and B. megaterium (in vitro).
What are the official names of this protein?
Cathelicidin antimicrobial peptide.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYGB_VIBPA
Sequence: MAKEFLIELGTEELPPTQLRTLAEAFAANFEAELKGAELAHEGVKWFAAPRRLALKVAALAESQSDKVVEKRGPAVSAAFDAEGNPTKAAQGWARGCGITVDQADRMVTDKGEWLLFKQEVKGQPTSEIVVELAAKALANLPIAKPMRWGNKTTQFIRPVKTLTMLMGSDLIEGEILGVASSRTIRGHRFMGEKEFTIDSAEQYPAILEERGKVMADYEARKAIILADAQKAAAAVGGIADLEDDLVEEVTSLVEWPVVLTAKFEEEFLKVPSEALVYTMKGDQKYFPVYDENKKLLPNFIFVSNIESKEPRYVIEGNEKVVRPRLADAEFFFNTDRKRPLIDRLPELEQAIFQQQLGTIKDKTDRITELAGYIAEQIGADVEKSKRAGLLAKCDLMTSMVFEFTDTQGVMGMHYARHDGEAEEVAVALNEQYMPRFAGDELPSNGVSTAVAMADKLDTIVGIFGIGQAPKGSDPFALRRASLGVLRIIVEYGYNLDLVDLVAKAKSLFGDRLTNDNVEQDVIEFMLGRFRAWYQDEGFSVDIIQAVLARRPTKPADFDQRVKAVSHFRELEAAESLAAANKRVGNILAKFDGELAEEIDLALLQEDAEKALAESVEVMTEALEPAFATGNYQEALSKLADLREPVDAFFDNVMVMADDEALKKNRLTLLNNLRNLFLQIADISLLQK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_ECOK1
Sequence: MERYESLFTQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEVLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAECEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKAFVQPMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: HUTI_PORG3
Sequence: MPNTPHTMNLYIKNIAQLVTCQGTEAKHGREAMGQIHTIEGPAAVVIRDGIITFAGRMADVAPSMTEGCRELDATGRCVLPGFVDSHTHLVFGGYREDEFQWRLAGDSYMSIMERGGGIASTMRATRAESEDELKASAHRHLSNMMKMGVTTVEAKSGYGMNLETELKQLRVVRDLQDEQPLDLYSTFMGAHDTAPEYKGRPTEFIEYLCREVLPEVVRQNLAECCDIFTEKGVFDHEQTRRMLTAAKEAGLSVKMHADEIVPFGGAELAAELGCLSADHLLRISDAGIKALAESNTVATLLPCTAFSLRADYAPARKMIDAGCAVALGSDLNPGSCFSASVPLMFALATLYMGMTVEEAITALTINGAAAIGRADTIGSIEPGKKGDLVVLQYPSYKFLSYHFGMNLVEHTVKGGRVVYTNS
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2C62_ORYSJ
Sequence: MAGKEIYHKMKDKVKDAFSSSGPETGKGKTKLSGKRVKHGYHLVKGKSNHPMEDYLVAEYRQEGEHDLGLFAIFDGHLGHTVPDFLRSHLFDNILKQPEFLSNPQAAIRNAYQLTDAKILESAAELGRGGSTAVTAILISSENSVNLVVANVGDSRAVISKSGVAKQLSVDHEPNKERHSIEKKGGFVSNLPGDVPRVDGQLAVARAFGDRSLKKHLSSEPDVVEEPIDENTDFLILASDGLWKVMSNQEAVDEIKDFKDAQAAAKHLTEQAVNRKSKDDISCIVVKFLC
What are the official names of this protein?
Probable protein phosphatase 2C 62, OsPP2C62.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: DNAK_PROMT
Sequence: MGKVVGIDLGTTNSCVAVMEGGKPTVIANAEGFRTTPSVVAYTKNQDQLVGQIAKRQAVMNPENTFYSSKRFVGRRVDEVNDESKEVSYGVEKAGSNVKIKCPILDKQFSPEEVSAQVLRKLSDDAGKYLGETVTQAVITVPAYFNDSQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKKSNERILVFDLGGGTFDVSVLEVGDGVFEVLSTSGDTHLGGDDFDRVIVDHLASTFKGNEGIDLRQDKQALQRLTEAAEKAKIELSNATQSEINLPFITATPEGPKHLDLTLTRGKFEELASNLIDRCRVPVEQALKDAKLSTGEIDEIVMVGGSTRMPAVKELVKRVTTKDPNQTVNPDEVVAVGAAIQGGVLAGEVKDILLLDVTPLSLGVETLGGVMTKMISRNTTVPTKKAETYSTAVDGQTNVEIHVLQGEREMASDNKSLGTFRLDGIPPAPRGVPQIEVTFDIDANGILSVNAKDKGSGKEQSISITGASTLSDNEVDKMVKDAEMNASADKEKREKIDIKNQAETLVYQAEKQIGELGDKVDEAAKAKVEEKRIKLKEATEKDDYESMKTLVEELQQELYSLGASVYQQANDASQAAADSNTDSKVDGDDVIDADFTETK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SARDH_HUMAN
Sequence: MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPSRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTERIEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRRLLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSRPPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHITTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGHLVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLEAIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQAHLKSPFDPNNKRVKGIY
What is the function of this protein?
Catalyzes the last step of the oxidative degradation of choline to glycine.  Converts sarcosine into glycine.
What are the official names of this protein?
Sarcosine dehydrogenase, mitochondrial, SarDH, BPR-2.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL15_ANADF
Sequence: MSLSKLKAPKGANRERTRVGRGQGSGLGKTAGRGGKGQKARSGNMHFEGFEGGQMPLQRRLPKFGFKNVFRREFEEVKVGDLDGLSGVVDPAALKGAGLVRGNRDGVVVLGGGELKSAVTVKVHRVTAGARAAIEKAGGTVELIPAPVTMYEKAKAARKAQAKK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ALLC_PSEU2
Sequence: MKVYAAPFEKFVNLADARLGTRILSVTDDWFADANRLFQPTPAVWKEGVFDDNGKWMDGWESRRKRFEGYDSAVIRLGVAGTIKGVDIDTSFFTGNFPPSASLEACFLASGEPDENTAWTEVLPSVELQGNSHHYHEINNDQAFSHLRFNIYPDGGVARLRVYGVPHRDWSKVSADEQIDLVAALNGGRSIACSDEHYGSMSNILNPGRGVNMGDGWETARRRTPGNDWVIVALGHKGEVEKVIVDTLHFKGNYPDSCSIQGALVKGGTDSQIETQSLFWRELLPSQKLTMHAEHEFAEQIKAIGPITHIRLNVFPDGGVSRLRVLGKVAR
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: UPP_ESCF3
Sequence: MKIVEVKHPLVKHKLGLMRETDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEVDQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: CSPLB_RICCO
Sequence: MSYLGVGVSPGNVPVYHGSNLKVIDKRVRLAELVLRCLICGLGVLAAVLVGTDTQVKEIFSIQKKARFTDMKALVFLVIANGIAAAYSLLQGVRCVVGMVRGSALFSKPLAWAIFSGDQMMAYLTVAAVAAAAQSAVFAKLGQPELQWMKICNMYGKFCNQVGEGIASALLVSVSMVVLSCISAFSLFRLYGANKGKDCTRW
What are the official names of this protein?
CASP-like protein 2B1, RcCASPL2B1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KAS2_KASSE
Sequence: FIQYLAPLIPHAVKAISDLI
What is the function of this protein?
Has no antimicrobial activities against bacteria (E. coli and S. aureus) nor against the fungus C. albicans.
What are the official names of this protein?
Kassinatuerin-2.
What are the subcellular locations of this protein?
Secreted.
Protein: INT10_CHICK
Sequence: MSAQGDCEFLVKRARELVPGDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTASAGRLLYDMFVNFPDQPAVWREISVITAALRNDSQDKQTQFLRGLFETLPGRVQCEMLLKATEQCFNTLERAEMLLLLLRRFPETVVQHGVGLGETLLEAENIEDQESPVNCFRKLFVCDVLPLIINNPDVRLPASLLYKYLNKAAEFYINYVTRSTQTESQYQGSQDSSDLMSPSKRSSQKYIIDGLTEKSSQITDPWERLFKILSVVGMRCEWQMDKGRRSFGDILHRMKDLCRYISNFDSDAHAKYKNQVVYSTMLVFFKNAFQYVSNIQPSLFQGPNAPNQAPLILLEDVTNVYGDTDIDRNKHIHKKRKLAEGREKTMSSDDEDPSGKARSRHIAVNKADLANSIEVLESFKLARESWELLCSLESLDKEFTRICLSWKTETWLWLRIFLTDMIIYQGQYKKAISSLHHLAALQGSHSPQQITGQGSLENQRALIQLATCHFALGEYRQTCEKVLDLMCYILLPIQEGGKVQEEQPKVKSKFRKGSDLKLWPCTSRAIMPYCLHLLLACFKLRAFTDNRDDTALGHVIVLLQHEWPRGENLFLKAINKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLS
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 10, Int10.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CQG3_CONFL
Sequence: MHTLEMLLLLLLLLPLALGEGDGQAVAGDRNPSEARSTHEHFLQRLIRLIHGSDCQPCGQYVCCPPWKYAEYRRFT
What are the official names of this protein?
Conotoxin Fla16d, Conotoxin Fla16.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin Q superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TSIV1_VIBCH
Sequence: MKLLNNLAIKKLISVVVLFIALFFLGYDYYQTSQPNIWGDEPDESYITISGKKPIDAYLEVWTHFWVTGDECEAYSYDLFGQKAHQGGKISQKITHDFAKDGSNFEFRIPYQTYKNSQNCIVELRDFSIQAHNDFDTVGFAQLRFSPAGREYYNREVDLNSLITADNCNSDIFKSIRKEWAGAIGCHFYVDGKKKTKDEEFNAYTIYYDFSKFNNDTVIHYDILAGENYRSEPLSSAQKTAVVSDDN
What is the function of this protein?
Immunity protein that plays a role in preventing early activation of toxin TseL.
What are the official names of this protein?
Immunity protein TsiV1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ISCS_PSEU2
Sequence: MKLPIYLDYSATTPVDPRVAQKMIDCLTVEGNFGNPASRSHVFGWKAEEAVENARRQVADLVNADPREIVWTSGATESNNLAIKGVAHFYASKGKHLITSKVEHKAVLDTTRQLEREGFEVTYIEPGEDGLITPAMIEAALRDDTILVSIMHVNNEIGTINDIAAIGELTRSRGVLFHVDGAQSTGKVEIDLASLKVDLMSFSAHKTYGPKGIGALYVSRKPRVRLEATMHGGGHERGMRSGTLATHQIVGMGEAFRIAKEEMAAENVRIKALSDRFFKQVENLEELYVNGSLTARVPHNLNLSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGRNDELAHSSIRFTFGRFSTEEEIDYAAQKVCEAVTRLRTLSPLWDMFKDGVDISKIEWAAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3502_YERP3
Sequence: MFRWGIIFLIIALIAAALGFGGLAGTAAWAAKVVFVVGIILFLISLFTGRKRL
What are the official names of this protein?
UPF0391 membrane protein YpsIP31758_3502.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROE_CITBB
Sequence: MTITGKTKVAGIIGWPVSHSLSPPMHNAAFEALGLDFTYVPFPVAPERLAAGIAGLAALGVVGFSVTIPHKVAILPLLDRVTPEAELIGAVNTVAVEEGALTGYNTDGIGLLSALRSKLGFHPEGRSVLVLGAGGAARSAVASLGLAGAGRVEVANRSPDAGRCLAEAMRERLAGTDFGFQPLGQISDKGYMSSFDLVVNTTSVGMAGDAFAGLDLAALKPGACVYDMVYAPPVTPLLAQAEAAGVPWANGLGMLAAQGEAAFRIWTGAIPPEGCMEKALAARLTTPGNP
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: HIS4_MYCSS
Sequence: MSEKRPLILLPAVDVVEGRAVRLVQGKAGSETEYGSALDAALGWQRDGAEWIHLVDLDAAFGRGSNRELLADVVGRLDVAVELSGGIRDDESLEAALATGCARVNIGTAALENPQWCAKVVAEFGDKVAVGLDVKIVDDQHRLRGRGWETDGGDLWEVLDRLDSEGCSRYVVTDVTKDGTLQGPNLDLLGRVADRTDAPVIASGGVSSLDDLRAIATLTDRGVEGAIVGKALYAGRFTLPEALAAMGQ
What is the function of this protein?
Involved in both the histidine and tryptophan biosynthetic pathways.
What are the official names of this protein?
Phosphoribosyl isomerase A, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, N-(5'-phosphoribosyl)anthranilate isomerase, PRAI, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF155_IIV3
Sequence: MTQVIVRNSLDKPFGKLANDAEVPLAVKTEDYSSVINYVYSNLLPFGTFREELMATPPSRVLSTFIQMRKHIKKSIIQSSAHTAIMVESERDPVFRQALLETSPQKIVYKSNNKFMGVGEDGTGDNIYGAALEQVRNELQAEKDRDAHQEAVYLAYIAEVNLKKALRKHNLEKYISKDRKRSIKRLVDALVQDYGKTQVFDNSPDIDTIMTLHEKRNIMVYTDPNALIRIVRKNTIRAVLAKNLLELRVAALNAFVDYAISKNVVRSEDKSRLKDQLFDIELGKRNDFSKRILDLFEAKALPDEIKNVIKKFKAQWYFPRDDEIEHFERETVKIPVPQATTTQQATAEPAETYTVSYDSDSVLSPLRRTQALNLNMLLFPTISHFIAFEVNKKYELTSIRGLYDTIKKIPIRTLDAWSKTHEQQTMEQRKLLLLEEAITHKLMDYSVKHLVWAIRDLKFEDKYNPDETTQIYRKYMDKINLRIQKIPSFEEFVEKDPMVHEVVREKVDFYFTILDNLMVHTKYKFNFKVSYDDLVKMSPFHGFILMDSVQISRLPIPDYLQWKNSRYGLSTESLVQIWTIVYNGLKQSEKLVGINDWDIRYKSCFIWAKYLLGQEIRSRRLNVMESRREDEVLLAILSVLFKLKEVNLRFGLSALNFQDLQTALYLCLGRVRQYVPKGNKPDLRPPPTLVADSMFDQPDIQLAPLVEPEEEVDETQVEIYEPEQMDDQEYNEYDYYRDYDEEFEGFNLNARKKFGIFFHEFYAPLENKIQLPELEDAINSFIKSSVPRSVKNQNLNFFITNFRVPDI
What are the official names of this protein?
Uncharacterized protein 113L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 155L family.
Protein: LSPA_RALSO
Sequence: MATRNNGKSKAAGSKSGGGHGVGPWLGLGVIWILLDQLTKIAILKTFAYGESRPITGFFNLVLAYNRGAAFSFLAAAGGWQRWFFTGLGVAAALFIVWLLKRHSGQKLFCFALALILGGALGNVIDRLVYGHVVDFLDFHLRGYHWPAFNVADCGICIGAVLLIIDELRRVRR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NEP_INCY6
Sequence: MSDKTVKSTNLMAFVATKMLERQEDLDTCTEMQVEKMKTSTKARLRTESSFAPRTWEDAIKDEILRRSVDTSSLNKWPELKQELENVSDALKADSLWLPMKSLSLYSKVSNQEPSSIPIGEMKHQILTRLKLICSRLEKLDLNLSKAVLGIQNSEDLILIIYNRDVCKNTILMIKSLCNSLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ATG23_CANGA
Sequence: MLNDILVEVAEKTQLLESLIIPHERALTESDYSDQLENIRAEISATLNSLSNLNDLLISHDGPLRTEISSLMASKSKLKKINMKELTLLNEQETLETLRNDSSNLESSRPGFTTQQQQSITIASSYRHELQKYLDLVDVEKTSLNTNKLADNSKISKEDVENSDFNFNLKRYEKQQSILHSALTVNEIEIKKLETLLKEFRKDNNFIRDELKLINSNLKSHEDLISDELKQIDESRYAIMQSIGYSGRNEQQSSILDSIVKLSIKKPDIRTLIQERIEEYSNLLNFIDMKLNGLDQMLQEYKSRKSEWAEKSILWSQCLALISELEVTVRDQLSSAHTVGSEISPDQIKAQIKKFLTKLNKLLDESDLEDVVYSLVRNEVNSLNVALDEMNQMPQIKNDISDRESIHNPSFKLISKSPPKTGFSSENVSYKLNNTNIKKD
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt) vesicle formation and efficient autophagy.  Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9.  Also plays a role in regulation of filamentous growth (By similarity).
What are the official names of this protein?
Autophagy-related protein 23.
What is the protein family that this protein belongs to?
Belongs to the ATG23 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: MIAB_PORG3
Sequence: MIEQIGADSKSAENKQERKLYIETYGCQMNVADSEVVASVMQMDGYSLTDNVDEADTILVNTCSVRDNAEQKVLNRLAYYHSLRKKRRASSRLVIGVLGCMAERVKEELIREHHVDVVAGPDSYLDLPNLVGAAEQGEKAINVELSMQETYKDVMPLKMGGVHINGFVSIMRGCNNFCSYCIVPYTRGRERSREIESILNEVRDLKAKNFREVTLLGQNVNSYRYEQNGRIIRFPDLLAAVAEAVPDMRIRFTSPHPKDMDDEAIAVMARYRNICNHIHLPAQSGSDKMLRVMKRGYTRRWYLDRVAAIRRAIPDCAISSDLFCGFHSETEEDFEATLSLMEEVGYDSAFMFKYSERPGTYAARHLVDDVLEEVKLARLDRMIALQNRLSEESNKRDISKTFEVLIEGFSKRSREQLFGRTQQNKVVIFDKNGHRVGQYIYVRIKDASSATLFGEVVEAPTSEKG
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_NEIMA
Sequence: MLLGVNIDHIATVRNARGTTYPSPVEAALVAETHGADLITMHLREDRRHIKDADVFAVKNAIRTRLNLEMALTEEMLENALKVMPEDVCIVPEKRQEITTEGGLDVLAQQDKIAEFTKILTDAGIRVSLFIDADDRQIQAARDVGAPVVELHTGAYADARSHAEQIRQFERIQNGAHFASDLGLVVNAGHGLTIHNVTPIAQILAIRELNIGHSLISQALFLGLPEAVRQMKEAMFRARLLP
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CADH1_BOVIN
Sequence: MGPWSRSLSALCCCCRCNPWLCREPEPCIPGFGAESYTFTVPRRNLERGRVLGRVSFEGCAGLPRTVYVSDDTRFKVHTDGVLTVRRPVHLHRPELSFLVHAWDSTHRKLSTKVTLEVSAHHHHHHSHHDSPSGTQTEVLTFPGPHHGLRRQKRDWVIPPISCPENEKGPFPKSLVQIKSNKEKETQVFYSITGQRADTPPVGVFIIERETGWLKVTQPLDREQIAKYILFSHAVSSNGQAIEEPMEIVITVTDQNDNKPQFTQEVFKASALEGALPGTSVMQVTATDIDDEVNTYTAAIGYTIPAQDPMLPHNKMFTINKETGVISVLTTGLDRESFPTYTLMVQAADLNGEGLSTTATAVITVLDTNDNAPRFNPTTYVGSVPENEANVAITTLTVTDADDPNTPAWEAVYTVLNDNEKQFIVVTDPVTNEGTLKTAKGLDFEAKQQYILYVAVTNVAPFEVTLPTSTATVTVDVIDVNEAPIFVPPQKRVEVPEDFGVGLEITSYTAREPDTFMEQKITYRIWRDTANWLEINPETGAISTRAELDREDVDHVKNSTYTALIIATDNGSPPATGTGTLLLFLDDVNDNGPVPEPRTMDFCQRNPEPHIININDPDLPPNTSPFTAELTHGASVNWTIEYNDQERESLILKPKKTLELGDHKINLKLIDNQNKDQVTTLDVHVCDCDGIVSNCRKARPAEAGLQVPAILGILGGILAFLILILLLLLLVRRRRVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPQYRPRPANPDEIGNFIDENLKAADSDPTAPPYDSLLVFDYEGSGSEAATLSSLNSSESDQDQDYDYLNEWGNRFKKLADMYGGGEDD
What is the function of this protein?
E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors.  Has a strong inhibitory effect on APP C99 and C83 production (By similarity).
What are the official names of this protein?
Cadherin-1, Epithelial cadherin, E-cadherin.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cell membrane; Single- pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Note=Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm (By similarity). Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane (By similarity).
Protein: U24_HHV6Z
Sequence: MDRPRTPPPSYSEVLMMDVMYGQVSPHASNDTSFVECLPPPQSSRSAWNLWNKRRKTFAFLVLTGLAIAMILFIAFVIYVFNVNRRKK
What is the function of this protein?
Down-regulates the TCR/CD3E complex and the transferrin receptor TFRC in host T-cells by blocking them from recycling back to the cell surface.
What are the official names of this protein?
U24 protein.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein.
Protein: RS13_LACH4
Sequence: MARIAGVDLPRDKRIVVALTYIYGIGNATAKKICADAGVSEDVRSKDLTPEDQEKLRTEVDKYRVEGDLRREVSMNIKRLVDIGSYRGIRHRRGLPVRGQNTKNNARTRKGTKRNR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.