PharMolix/UniProtQA huggingface dataset:
Protein: SPG2_STRSG
Sequence: MEKEKKVKYFLRKSAFGLASVSAAFLVGSTVFAVDSPIEDTPIIRNGGELTNLLGNSETTLALRNEESATADLTAAAVADTVAAAAAENAGAAAWEAAAAADALAKAKADALKEFNKYGVSDYYKNLINNAKTVEGVKDLQAQVVESAKKARISEATDGLSDFLKSQTPAEDTVKSIELAEAKVLANRELDKYGVSDYHKNLINNAKTVEGVKDLQAQVVESAKKARISEATDGLSDFLKSQTPAEDTVKSIELAEAKVLANRELDKYGVSDYYKNLINNAKTVEGVKALIDEILAALPKTDTYKLILNGKTLKGETTTEAVDAATAEKVFKQYANDNGVDGEWTYDDATKTFTVTEKPEVIDASELTPAVTTYKLVINGKTLKGETTTEAVDAATAEKVFKQYANDNGVDGEWTYDDATKTFTVTEKPEVIDASELTPAVTTYKLVINGKTLKGETTTKAVDAETAEKAFKQYANDNGVDGVWTYDDATKTFTVTEMVTEVPGDAPTEPEKPEASIPLVPLTPATPIAKDDAKKDDTKKEDAKKPEAKKEDAKKAETLPTTGEGSNPFFTAAALAVMAGAGALAVASKRKED
What are the official names of this protein?
Immunoglobulin G-binding protein G, IgG-binding protein G.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: CATB_MEDTR
Sequence: MAQWTLLIVFFCVATAAAGLSFHDSNPIRMVSDMEEQLLQVIGESRHAVSFARFANRYGKRYDTVDEMKRRFKIFSENLQLIKSTNKKRLGYTLGVNHFADWTWEEFRSHRLGAAQNCSATLKGNHRITDVVLPAEKDWRKEGIVSEVKDQGHCGSCWTFSTTGALESAYAQAFGKNISLSEQQLVDCAGAYNNFGCNGGLPSQAFEYIKYNGGLETEEAYPYTGQNGLCKFTSENVAVQVLGSVNITLGAEDELKHAVAFARPVSVAFQVVDDFRLYKKGVYTSTTCGSTPMDVNHAVLAVGYGIEDGVPYWLIKNSWGGEWGDHGYFKMEMGKNMCGVATCSSYPVVA
What is the function of this protein?
May play a role in proteolysis leading to mobilization of nitrogen during senescence and starvation.
What are the official names of this protein?
Pro-cathepsin H, Cysteine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Vacuole. Lysosome.
Protein: CLB4_ANOGA
Sequence: MIGNRVINLLIVATLALAGQTVLALELGQDCVNPVGEAGKCVLFRECQPLVDIYNKPVNTPDDTQFLTESRCGLYERKTLVCCAGVRSKGKTSLPESPNCGVQLTDRVIGGQPTKIDEFPWTALIEYEKPNGRFGFHCGGSVINERYILTAAHCITSIPRGWKVHRVRLGEWDLSSTTDQEDDFYADAPIDLDIEKIIVHPGYNLQDKSHHNDIALIRFNREINYSSTISAICLPLSNSLRNRKHAGLSSYAAGWGKTETASASQKKLKVELTVVDVKDCSPAYQRNGISLDSTQMCAGGIRGKDTCSGDSGGPLMRQMSGSWYLIGVVSFGPQKCGAPGVPGVYTNVAEYVDWIKDNIY
What is the function of this protein?
Probable serine protease which plays a role in the innate immune response against parasite P. bergei infection by activating the melanization cascade (PubMed:16922859).  In the resistant strain L3-5, involved in the melanization of killed parasite P. berghei ookinetes which results in their clearance (PubMed:16922859).  In the susceptible strain G3, appears to be dispensable for ookinete elimination which occurs by lysis (PubMed:16922859).
What are the official names of this protein?
CLIP domain-containing serine protease B4, CLIP domain-containing serine protease 14D, AgSp14D1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS11_CHLPM
Sequence: MATTSRKKKKVKVTPEGAVHIKASFNNIMITITDVQGNTVSWSSAGKNGFRGSKKNTPYASQVTSEAAAKEAYDLGMRHVDVFIKGPGAGRDAAIRALQGVGLEVRTIKDITPLPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DYT2B_BOVIN
Sequence: MSVAASFPKHTSFTMRASFAAADGLPETENNAGEPENTYILRPVFQQRFRPSVVKDCIHAVLKEELANAEYSPEEMPQLTKHLSENIKDKLKEMGFDRYKMVVQVVIGEQRGEGVFMAARCFWDADTDNCTHDVFMNDSLFCVVAAFGCFYY
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system.  Required for proper retrograde ciliary transport.
What are the official names of this protein?
Dynein light chain Tctex-type protein 2B, Tctex1 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain Tctex-type family.
What are the subcellular locations of this protein?
Dynein axonemal particle.
Protein: Y1399_STRP6
Sequence: MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVDWFIFTGNLGFEQWALEVANELKEEYPLQIGTIFLFETHGDRWNEKNQEVLSQFRAVDFVKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLLTFDRLNDMSQS
What are the official names of this protein?
UPF0398 protein M6_Spy1399.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: OGL_PECAS
Sequence: MAKGNKIPLTFHTYQDAATGTEVVRLTPPDVICHRNYFYQKCFFNDGSKLLFGAAFDGPWNYYLLDLKEQNATQLTEGKGDNTFGGFLSPNDDALYYVKNTRNLMRVDLTTLEEKTIYQVPDDWVGYGTWVANSDCTKMVGIEIKKEDWKPLTDWKKFQEFYFTNPCCRLIRVDLVTGEAETILQENQWLGHPIYRPGDDNTVAFCHEGPHDLVDARMWFINEDGTNMRKVKEHAEGESCTHEFWVPDGSAMIYVSYLKDDTNRYIRSIDPVTLEDRQLRVMPPCSHLMSNYDGTLLVGDGSDAPVDVQDDGGYKIENDPFLYVFNLKTGKEHRIAQHNTSWEVLEGDRQVTHPHPSFTPDNKQVLFTSDVDGKPALYLAKVPDSVWN
What is the function of this protein?
Involved in degradation of pectin, which causes soft-rod disease in plants.
What are the official names of this protein?
Oligogalacturonide lyase.
What are the subcellular locations of this protein?
Periplasm.
Protein: DCUP_CAMLR
Sequence: MIFVDACFKKSTPYTPVWMMRQAGRYLPEYMEVRASAGDFLSLCKDYKKASEVTLQPVDILGVDAAIIFSDILVVPLEMGMDLKFEKGEGPVFSNPIKTKEDLERLDVEKSIKNLSYVYDALALTREKLAHDKALIGFCGSPWTIATYMIEGGGSKNYAKCKKLVYQNPEFLHQILSKLTLALKHYIQEQIKAGANAVQIFDSWASALEEEMFFEFSFKYMLEIADFIKEKYPHIPVILFPKGVSGFLDNINGNFDVFGVDWSTPLELAKEKLGAKYTLQGNMEPCRLYDKKAIEVGVDKILNIMQDSAHIFNLGHGILPDIPVENAKYFIKLVQEKSKK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_SHESR
Sequence: MKTFTATPETVTRDWFVVDADGKTLGRIATEIALRLRGKHKPEYTPHVDTGDYIIVINAEKVTVTGNKAQGKTYYSHSGFPGGIKQISFEKLQAHKPEMIIEKAVKGMLPKGPLGRAMFRKLKVYAGAEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL35_PEDPA
Sequence: MPKMKTNRAAAKRFKKTANGGLKSANAYTSHRFHGKTKKQRRQLRGTDMMDSTNVKRYKKLLSNI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: Y1248_BACAH
Sequence: MRIMARIGVENSLTDVQQALKQQGHEVVTLNSEQDAQGCDCCVVTGQDSNMMGIADASIKGSVITAHGLTTDDICQQVESRT
What are the official names of this protein?
UPF0180 protein BALH_1248.
What is the protein family that this protein belongs to?
Belongs to the UPF0180 family.
Protein: MRAY_STRZP
Sequence: MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGFSNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKPAKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTNN_STAA8
Sequence: MIGIIGAMEEEVTILKNKLTQLSEISVAHVKFYTGILKDREVVITQSGIGKVNAAISTTLLINKFKPDVIINTGSAGALDESLNVGDVLISDDVKYHDADATAFGYEYGQIPQMPVAFQSSKPLIEKVSQVVQQQQLTAKVGLIVSGDSFIGSVEQRQKIKKAFPNAMAVEMEATAIAQTCYQFNVPFVVVRAVSDLANGEAEMSFEAFLEKAAVSSSQTVEALVSQL
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: LACD_STAAW
Sequence: MSKSNQKIASIEQLSNNEGIISALAFDQRGALKRMMAKHQTEEPTVAQIEQLKVLVAEELTQYASSILLDPEYGLPASDARNKDCGLLLAYEKTGYDVNAKGRLPDCLVQWSAKRLKEQGANAVKFLLYYDVDDAEEINIQKKAYIERIGSECVAEDIPFFLEVLTYDDNIPDNGSVEFAKVKPRKVNEAMKLFSEPRFNVDVLKVEVPVNMKYVEGFAEGEVVYTKEEAAQHFKNQDAATHLPYIYLSAGVSAELFQETLKFAHEAGAKFNGVLCGRATWSGAVQVYIEQGEDAAREWLRTTGFKNIDDLNKVLKDTATSWKQRK
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase, D-tagatose-1,6-bisphosphate aldolase, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: C79D3_LOTJA
Sequence: MGLMPDFLSLCHEFPWTFLLVVIFSFMIFKVTKTHLVNKSKKYKLPPGPKPWPIVGNLPEMLANRPATIWIHKLMKEMNTEIACIRLANTIVIPVTCPTIACEFLKKHDASFASRPKIMSTDIASDGFITTVLVPYGEQWKKMKRVLVNNLLSPQKHQWLLGKRNEEADNLMFYIYNKCCKDVNDGPGLVNIRIAAQHYGGNVFRKLIFNSRYFGKVMEDGGPGFEEVEHINATFTILKYVYAFSISDFVPFLRRLDLDGHRSKIMKAMRIMRKYHDPIIDDRIKQWNDGLKTVEEDLLDVLIKLKDANNKPLLTLKELKAQIIELAIEMVDNPSNAFEWALAEMINQPELLKRATEELDNVVGKERLVQESDIPKLQFVKACAREALRLHPMEYFNVPHLCMNDTMVGDYLFPKGTQVLLSRVALGRNPKFWTDPLKFNPERHLKEGIDVVLTEPDLRFISFTTGRRSCPGVALGTTMTVMLFARMLHGFSWSPPPDVSSIDLVPSKDDLFLAKPLLLVAKPRLAAELYRTNEI
What is the function of this protein?
Involved in the biosynthesis of the cyanogenic glucosides linamarin and lotaustralin and of the nitirle glucosides rhodiocyanoside A and D.  Can use L-isoleucine > L-valine as substrate, but not L-leucine, L-phenylalanine or L-tyrosine.
What are the official names of this protein?
Isoleucine N-monooxygenase 1, Cytochrome P450 79D3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein.
Protein: TXPR1_THRPR
Sequence: ECRYWLGGCSAGQTCCKHLVCSRRHGWCVWDGTFS
What is the function of this protein?
Ion channel impairing toxin that inhibits voltage-gated calcium channel Cav3. 1/CACNA1G (IC(50)=53 nM), voltage-gated potassium channels Kv2. 1/KCNB1 (IC(50)=411 nM), all sodium channels tested (Nav1. 2/SCN2A (IC(50)=60-104 nM), Nav1. 5/SCN5A (IC(50)=76-358 nM), Nav1. 6/SCN8A (IC(50)=21-133 nM), Nav1. 7/SCN9A (IC(50)=51-95 nM), and Nav1. 8/SCN10A) and the nociceptor cation channel TRPA1 (IC(50)=389 nM) (PubMed:12475222, PubMed:17087985, PubMed:20351484, PubMed:24886690, PubMed:29703751, PubMed:31234412, PubMed:24530065).  Acts as a potent and selective blocker of voltage-gated calcium channel Cav3. 1/CACNA1G, but not of Cav3. 2/CACNA1H, and Cav3. 3/CACNA1I (PubMed:20351484, PubMed:24886690).  On Nav1. 7/SCN9A, primarily interacts with the DII and DIV voltage-sensor domains (PubMed:32511987).  Also acts as an inhibitor of nociceptor cation channel TRPA1 (IC(50)~389 nM) by binding to the S1-S4 gating domain of TRPA1 (PubMed:24530065).  It shows moderate affinity for lipid bilayers (PubMed:29703751).
What are the official names of this protein?
Beta/omega-theraphotoxin-Tp1a, Beta/omega-TRTX-Tp1a, Protoxin-1, ProTx-1, ProTx1, Protoxin-I, ProTx-I.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 54 (ProTx-1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FER_MYCTU
Sequence: MTYVIGSECVDVMDKSCVQECPVDCIYEGARMLYINPDECVDCGACKPACRVEAIYWEGDLPDDQHQHLGDNAAFFHQVLPGRVAPLGSPGGAAAVGPIGVDTPLVAAIPVECP
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
Protein: ATP6_ACTSZ
Sequence: MAGTTAGYIGHHLTFLSSGEGFWAVHLDTLFFSIVSALIFLFVFRNVAKKATSGVPGKLQCMVEIVVEWINGIVKENFHGPRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQLAGLFGIHYLRAVPTADISATLGMSLCVFALILFYTVKSKGFGGLVKEYTLHPFNHWTLVPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANAAIAALGIPLHLAWAIFHILIITLQAFIFMMLTVVYLSIAYNKAEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: K1B2_BUNCI
Sequence: ACKDGFPTATCQHAKLVGNCKNSQKYRANCAKTCGPC
What is the function of this protein?
Inhibits voltage-gated potassium channels (IC(50)=14. 42 nM for rKCNA1/Kv1. 1, IC(50)=80. 4 nM for rKCNA2/Kv1. 2, IC(50)=7. 76 nM for rKCNA6/Kv1. 6, IC(50)=13. 12 nM for hKCNA3/Kv1. 3, and IC(50)=49. 14 nM for insect Shaker IR).  Binds the Shaker IR channels in a voltage-independent manner.
What are the official names of this protein?
Kappa-actitoxin-Bcs3b, Kappa-AITX-Bcs3b, Potassium channel toxin BcsTx2, BcsTx2.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 1 potassium channel toxin family. Type 1b subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: B910_XENLA
Sequence: MKEEIAATVVFLTMLVKKHKQLSKQKIEKFAAKLTTILFAKYKNHWYAENPMKGQAFRCIRINTYQAIDAVFEKACAESNVDFNDLGLPKEMTIWVDPFEVCCRYGEKNDPFTIASFKGKDGYNAPKRISHAVEKATSDYYSGTSSDEELTNKEPKTIPKVSNPNSIYQCADYSQAIPSWSQYPRRKNYQNNGYPPNPPMPYYPQQKAYKAFRQSSAFSGPRVDRYHWVNMKRSAIS
What are the official names of this protein?
Maternal B9.10 protein, p30 B9.10.
What is the protein family that this protein belongs to?
Belongs to the BTG family.
Protein: RPOB_NOSS1
Sequence: MSSKKFNQVDKGRGMISENYIEPAFLLPDLIEIQRSSFRWFLEEGLIEELNSFSPITDYTGKLELHFLGHNYKLKEPKYSVEEAKRRDSTYAVQMYVPTRLLNKETGDIKEQEVFIGDLPLMTDRGTFIINGAERVIVNQIVRSPGVYYKSEIDKNGRRTYSASLIPNRGAWLKFETDRNDLVWVRIDKTRKLSAQVLLKALGLSDNEIFDALRHPEYFQKTIEKEGQFSEEEALMELYRKLRPGEPPTVLGGQQLLDSRFFDPKRYDLGRVGRYKLNKKLRLSVPDTVRVLTSGDILAAVDYLINLEYDIGSIDDIDHLGNRRVRSVGELLQNQVRVGLNRLERIIRERMTVSDAEVLTPASLVNPKPLVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGFAVRDIHPSHYGRICPIETPEGPNAGLIGSLATHARVNQYGFLETPFRPVENGRVRFDQPAAYMTADEEDDLRVAPGDIPVDENGYIIGPQVPVRYRQEFSTTTPEQVDYVAVSPVQIVSVATSMIPFLEHDDANRALMGSNMQRQAVPLLKPERPLVGTGLEAQGARDSGMVIVSRTDGDVVYVDATEIRVRVSGQLPTASGKSTDNGQLTSQKGQEIRYTVSKYQRSNQDTCLNQKPLVRIGERVVAGQVLADGSSTEGGELALGQNIVVAYMPWEGYNYEDAILISERLVQDDIYTSIHIEKYEIEARQTKLGPEEITREIPNVGEDALRQLDEQGIIRIGAWVEAGDILVGKVTPKGESDQPPEEKLLRAIFGEKARDVRDNSLRVPNGEKGRVVDVRLFTREQGDELPPGANMVVRVYVAQKRKIQVGDKMAGRHGNKGIISRILPIEDMPYLPDGSPVDIVLNPLGVPSRMNVGQVFECLLGWAGHTLGVRFKITPFDEMYGEESSRRIVHGKLQEARDETGKDWVYNPDDPGKIMVYDGRTGEAFDRPVTIGVAYMLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRFGEMEVWALEAFGAAYTLQELLTVKSDDMQGRNEALNAIVKGKAIPRPGTPESFKVLMRELQSLGLDIAVHKVETQADGSSLDVEVDLMADQLARRTPPRPTYESLSRESLDDDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: EXOC6_HUMAN
Sequence: MAENSESLGTVPEHERILQEIESTDTACVGPTLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKMCNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENYYRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPMSQSVPHIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPHIGLTELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKLNQKIDEFVQLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQHLSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHM
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.  Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity).
What are the official names of this protein?
Exocyst complex component 6, Exocyst complex component Sec15A, SEC15-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SEC15 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Midbody, Midbody ring. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation. Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214).
Protein: SI1L2_MOUSE
Sequence: MSDPRPSQAEKHKLGRAAAKLKDPSRTMQADDYFARKFKAINGSMGPATLNTSSSSEGGGGGGGPANGTPAVPKMGVRARVSEWPPKKDCSKDLACKTLWESRSQSSYESVTSIIQNGQNDQGDRQPEEQLDLDFVEAKYTIGDIFVHSPQRGLHPIRQRSNSDITISDIDTEDVLDQHAVNPNTGAALHREYGSTSSIDRQGLSGENVFAMLRGYRIESYDPKVTGSFGFPDFFPCDTAISPSLHAAAQISRGEFVRISGLDYMDGGLLMGRDRDKPFKRRLKSESVETSLFRKLRAVKSEHETFKFTSDLEEGRLDRGIRPWSCQRCFAHYDVQSILFNINEAMATRASVGKRKNITTGASAASQTPVPVGPAGGCESPLGSKEDLNSKENPDADEGDGKSNDLVLSCPYFRNETGGEGDRRIALSRANSASFSSGESCSFESSLSSHCTNAGVSVLEVPRESQPIHREKVKRYIIEHVDLGAYYYRKFFYGKEHQNYFGIDENLGPVAVSIRREKVEDPREKEGSQFNYRVAFRTSELTTLRGAILEDAVPSTARHGTARGLPLKEVLEYVIPELSIQCLRQAANSPKVPEQLLKLDEQGLSFQHKIGILYCRAGQSTEEEMYNNETAGPAFEEFLDLLGQRVRLKGFSKYRAQLDNKTDSTGTHSLYTTYKDFELMFHVSTLLPYMPNNRQQLLRKRHIGNDIVTIVFQEPGALPFTPKNIRSHFQHVFVIVKVHNPCTENVCYSVGVSRSKDVPPFGPPIPKGVTFPKSAVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAENFVTTATVDTSAKFSFITLGAKKKERVKPRKDAHLFSIGAIMWHVVARDFGQSADIECLLGISNEFIMLIEKDSKNVVFNCSCRDVIGWTSGLVSIKAFYERGECLLLSSVDNRSEDIREIVQRLLIVTRGCETVEMTLRRNGLGQLGFHVNFEGIVADVEPFGFAWKAGLRQGSRLVEICKVAVATLTHEQMIDLLRTSVTVKVVIIQPHEDGSPRRGCSELCRIPMVEYKLDSEGTPCEYKTPFRRNTTWHRVPTPALQPVSRASPVPGTPDRLQCQPLLQQAQAAIPRSTSFDRKLPDGTRSSPSNQSSSSDPGPGGSGPWRPQVGYDGCPSPLLLEHQGPGSVECDGTGEQEDLLEGGRLPETKWHGPPSKVLSSYKERVLQKDGSCKESPNKLSHIGDKSCSSHSSSNTLSSNTSSNSDDKHFGSGDLMDPELLGLTYIKGASTDSGIDTTPCMPATILGPVHLTGSRSLMHSRAEQWADAADVSVADDDPAKMYALHGYASAISSSAADGSMGDLSEVSSHSSGSQHSGSPSAHCSKSTGSLDSSKVYIVTHGGGQQAPGAVTKPYHRQGAANKYVIGWKKSEGSPPPEEPEVTECPRIYGEMDIMSTATQHPAVVGDSVSETQHVLSKDDFLKLMLPDSPLVEEGRRKFSFYGNVSPRRSLYRTLSDESVCSNRRGSSFASSRSSILEQALPNDILFSTTPPYHSTLPPRTHPAPSMGSLRNEFWFSDGSLSDKSKCADPGLMPLPDTAAGLDWSHLVDAARAFEGLDSDEELGLLCHHASYLDQRVASFCTLTDLQHGQELEGAPELSLCVDPTSGKEFMDTPGERSPSTLTGKVNQLELILRQLQTDLRKEKQDKAVLQAEVQHLRQDNMRLQEESQTATAQLRKFTEWFFSTIDKKA
What are the official names of this protein?
Signal-induced proliferation-associated 1-like protein 2, SIPA1-like protein 2.
Protein: LEU1_AZOVD
Sequence: MPMLKDPSQKYRPFAPIALRDRTWPDRVIDKAPLWLSTDLRDGNQSLIEPMDAAKKMRFFKTLVQVGLKEIEVGFPSASQTDFDFVRELIEGGHIPDDVTIQVLTQARDDLIERTFESLKGAKKAIVHYYNACAPSFRRIVFDQDKEGVKRIAVAAGRTIKRLAAAAPETRWGFEYSPEVFSSTESDFAVEVCNAVVEVFQPTPANRLILNLPATIECATPNHYADQIEWFCRHVDRRDSVIVSLHTHNDRGTGVAASELGLMAGADRVEGCLFGNGERTGNVDLVTLALNLYTQGVDPGLDFSDIDAVRKVVEECNQLPVHPRHPYVGDLVHTAFSGSHQDAIRKGFAQQDPEGVWEVPYLPIDPADIGRSYEAVIRVNSQSGKGGIAYLLEQEYGISLPRRMQIEFSQVVQKETDRLGLEMSAAQIHALLEAEYLRAETPYALKGHRLQEENGTCALDVEVFDKGESRHWRGIGKGPLEALVACLPVRVEIMDYHEHAIGAGSHARAAAYIELRLDGQRSLHGLGIDENLTTASIRALFSALNRALGQQASIRAA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: PCNA_COTJA
Sequence: MFEARLVQGSVLKRVLEALKDLITEACWDLGSGGISLQSMDSSHVSLVQLTLRSEGFDTYRCDRNIAMGVNLNSMSKILKCAGNEDIITLRAEDNADTLALVFETPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSAEFARICRDLSHIGDAVVISCAKDGVKFSANGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHXKYYLAPKIEDQQEGS
What is the function of this protein?
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
What are the official names of this protein?
Proliferating cell nuclear antigen, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TTH_ACIF2
Sequence: MPSIVRNHGPHNKILLSALLLALFGWVPLASAAVAVPMDSTGPYRTVSHPENAPSGVDAGVGPSEWTHAYANPAHNAAFPVPDDAPEWIRNGVSWLFPEARAWPLANPPFGSKTYGAAEASVTQTQFYGNALGPSVVDGVVYAESDDMFAYAVNAKTGKLIWRASPVGNNLMGNPLVIGNTVYLSAGSVAFNFANVLRYAHNPSASARGLNVSFNGIYALNRSNGKLLWYFATPGETMATPAYDNNTLFIADGAGNAFGINATTGKQVWKTHVGGMDNMSSVTAYRHNIYFAMAIKPYLYCLNESNGHIVWKGTIPGASNTGIGDVSPAAADGVVVLDATTKPQANKKAMFSNVIRAFDAKTGAVLWTRNMGSGGKIPAFKGGVPMIHNNIVYVGNPVASTYQAYELKTGKLLWTWHVPTKVAAGAGRSAPTYYKGLLYITTGQYIFVVNPATGKELHQHHIGGQFGIESPVIVGGTVYLTNSWDWIMAIPLKTISHGS
What is the function of this protein?
Catalyzes the hydrolysis of tetrathionate to generate elemental sulfur, thiosulfate and sulfate.
What are the official names of this protein?
Tetrathionate hydrolase, 4THase, TTH.
What is the protein family that this protein belongs to?
Belongs to the tetrathionate hydrolase family.
What are the subcellular locations of this protein?
Cell membrane. Note=Membrane-associated.
Protein: NUOA_NITMU
Sequence: MNASATQATEIWPLVAYFFLVVMLVVGVMALSYIIGERHRSKATDEPFESGIVTVGLARFRLSAKFYLIAVFFVIFDVEAVFLFAWAVAFRELGWPGYIEAIIFISILGAALAYLWRLGALDWGPPRHSAGRFAKDSRSPNHAVVSK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.