PharMolix/UniProtQA huggingface dataset:
Protein: SIGL7_HUMAN
Sequence: MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWMGTSVSPLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK
What is the function of this protein?
Putative adhesion molecule that mediates sialic-acid dependent binding to cells.  Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid.  Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide).  The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.  In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.  Mediates inhibition of natural killer cells cytotoxicity.  May play a role in hemopoiesis.  Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
What are the official names of this protein?
Sialic acid-binding Ig-like lectin 7, Siglec-7, Adhesion inhibitory receptor molecule 1, AIRM-1, CDw328, D-siglec, QA79 membrane protein, p75.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DLT1_YEAS2
Sequence: MSGFAKLKSWLYKASLFVSLILLIGFSVVLPIDSIAQASKSENNAFNTFIVVGALVVFGVFCIFIIIGRMLFHKSCLKDIPRRYIPITPADLPHRSSREAVLQNMERSKELTILLKKPKDPVIHDGLEPPRRCDYPLDEKLFPEYLNYADCIKSLTDRLKYHGLFLNNLDVRMNLEDTFADVVNSQFVNHNANKIQLEKAKEFIDLYETIRFSGKDVTRDQFIKFVKFCLYFGEVSLTRDTSFANLHNFKLNGSSNNIGRTESEYSINPFDENEYAQDDMHYFPEPPTHLVRESSISTVARHVSSGVDLTNSEEHPLDTDSDCNALRLKLSKADSYRSVIRH
What is the function of this protein?
Required for growth under high-pressure and low-temperature conditions.
What are the official names of this protein?
Defect at low temperature protein 1.
What is the protein family that this protein belongs to?
Belongs to the DLT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CVC2_VZVD
Sequence: MTARYGFGSISFPNKCGIFLSTTKNFIAPNFPIHYWTAPAFELRGRMNPDLEKNTLTLKNAAAVAALDNLRGETITLPTEIDRRLKPLEEQLTRMAKVLDSLETAAAEAEEADAQSEECTRTEIIRNESIHPEVQIAKNDAPLQYDTNFQVDFITLVYLGRARGNNSPGIVFGPWYRTLQERLVLDRPVAARGVDCKDGRISRTFMNTTVTCLQSAGRMYVGDRAYSAFECAVLCLYLMYRTSNSVHEPQVSSFGNLIEHLPEYTETFVNYMTTHENKNSYQFCYDRLPRDQFHARGGRYDQGALTSHSVMDALIRLQVLPPAPGQFNPGVNDIIDRNHTAYVDKIQQAAAAYLERAQNVFLMEDQTLLRLTIDTITALLLLRRLLWNGNVYGDKLKNNFQLGLIVSEATGTPTNNVILRGATGFDGKFKSGNNNFQFLCERYIAPLYTLNRTTELTEMFPGLVALCLDAHTQLSRGSLGRTVIDISSGQYQDRLISLIALELEHRRQNVTSLPIAAVVSIHDSVMLQYERGLGMLMHQPRVRAALEESRRLAQFNVNSDYDLLYFVCLGVIPQFASTP
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.  Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.
What are the official names of this protein?
Capsid vertex component 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: YABB_BACSU
Sequence: MVSLHDDERLDYLLAEDMKIIQSPTVFAFSLDAVLLSKFAYVPIQKGKIVDLCTGNGIVPLLLSTRSKADILGVEIQERLHDMAVRSVEYNKLDDQIQIIHDDLKNMPEKLGHNRYDVVTCNPPYFKTPKQTEQNMNEHLRIARHEIHCTLEDVISVSSKLLKQGGKAALVHRPGRLLEIFELMKAYQIEPKRVQFVYPKQGKEANTILVEGIKGGRPDLKILPPLFVYDEQNEYTKEIRTILYGDK
What is the function of this protein?
Methylates cellular RNA.
What are the official names of this protein?
Probable RNA methyltransferase YabB.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: PB2_ISAV8
Sequence: MDFISENTISDKTTLEELKNATLFQVTKVDDRDCLRARRICNAPKGHWAGLMEKAKAMGDPTEEEKDELKKIVESYNTVSVLGVSKSEGATGPRLVSSLKGLKNLLPGVNPKTLQETLLVGAPCPSTEPTTEEYWNVCRAAVGASMGSAKINMSQKVVMGASVIGWGQLNQSGPGVYFLNTKEIVTAEGKVDETRGPLERTSAPLMRDISRLIQETIEEVETGGDPSFSVRSEGGSKIEGRIAFSLHSEVSTLKMRIALEQKLAKYEYMGENLLTLVKNTSIDRMQPDSAMMGKMVLESLRTHTVSSEQLNGRMITVQSQGLETIAISSPFDVEYDDGYVFTRMKGNFVAVGRDYKGAILCFREGQGTFFSGRGNWSGLMEKCLVEMRLCPCFYSCTWQDYPDKKSLYEKATFEAKQIVFAMGENTGVDIRVNTDGEIGDKGISLLTREREDKYMSKVSYECRVVSGKLVMGLDKMSRVAKGNLEVVREKGDDTSQSDSFYEGVLQVGSMIGTTMESLKQQLQGPVGIWRASGVSAMERCMKRGQSKTVVASARYTFQKMMEKMATGREVSKYSLIIVMRCCIGFTSEANKRALTNISGTGYYISVAQPTVVKLAGEWLITPVGRSKTGEVQYVSAKLKKGMTTGKLELIKKADRSDLDNFPEPSADELLREGTIVLMQIGKDKWLCRVRTGDRRVRTDTDIQRAEAKSQVEKEDLMDEYGV
What is the function of this protein?
Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription.  Binds the cap of the target pre-RNA which is subsequently cleaved by PB1.  May play a role in genome replication (By similarity).
What are the official names of this protein?
Polymerase basic protein 2, PB2, Protein 3, P3, RNA-directed RNA polymerase subunit P3.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RL21_ECO55
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: F16PC_STAAS
Sequence: MTQITEKELKKKYLDLLSQNFDTPEKLATEIINLESILELPKGTEHFVSDLHGEYEAFQHVLRNGSGNVRAKINDIFKERLSTKELNDLTALVYYPEDKLKLIKSDFQSCGQLNVWYITTIEHLIELIKYCSSKYTRSKLRKALPKQYVYIIEELLYKSNEYQNKKSYYETLVNQVIELKQADDLIIGLAYSVQRLVVDHLHVVGDIYDRGPQPDKIMDTLINYHSLDIQWGNHDVLWVGAYAGSKVCLANLLRICARYDNLDIIEDAYGINLRPLLTLAEKYYDADNPAFKPKKRPDKHERLTQREESQITKIHQAIAMIQFKLEIPIIKRRPNFEMEERLVLEKVNYDTNEITVYGNTYPLKDTCFQTVNRDNPAELLPEEEEVMNKLLLSFQQSEKLRRHMSFLMRKGSLYLPYNGNLLIHGCIPVDENGEMESFEIDGHTYSGQELLDVFEYHVRKSFDEKENTDDLSTDLVWYLWTGKYSSLFGKRAMTTFERYFIADKASHKEEKNPYYHLREDVNMVRKMLSDFGLNADEGRIINGHTPVKEINGEDPIKADGKMLVIDGGFSKAYQSTTGIAGYTLLYNSFGMQLVAHQQFNAKEKILSEGIDELSIKRVVDKELQRKKIRDTNIGKDLQAQIDILKMLMHDRYLD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: SEPF_EXIS2
Sequence: MGFKTKMQNLFLGNTDDLDELEYENDATINKGRGASQQEYDEYYEDSTPTVTQKEDPVRQSNIVPIHTKKAKSQVILSEPRVFNEAQEIGEHLRQNRAVIVNMQRMSKDQSRQMINFLSGVVFALDGTITTISQNTLLCVPNNVELAGSISNLLGEDDINHKGW
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: CBG_SAISC
Sequence: MPLLLYTCLLWLLSSGLWTVQAMDPNAAYMNTSRHHRVLASVNADFAFSLYKHLVALSPKKNVFISPVSISMALAMLSLGTCGHTRAQLLHGLGFNLTEKSEAEIHQSFQHLHQLLAESDSSLEMTLGNALFLDGSLELLESFSADIKHYYESEVLTLNFQDWATTASRQINGYVKSKTQGKIDDLFSGLNSPAVLILINYIFFKGTWKQPFDLASTREENFYVDETTVVKVPMMFQSGTIRYLHDSELPCQLVQLNYAGNGTVFFILPEKGKMNIVITALSRNTIDRWSAGLTRSQVDLYIPKVTISGAYDFGGVLEDMGIADLFTNHANFSRITQDAQLKLSKVFHKAVLQLSEEGVNTTGSTGVTLNPMSKPIIMRFNQPFLIMVFDHFTWSSLFLGRVVNPA
What is the function of this protein?
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
What are the official names of this protein?
Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LR14B_DANRE
Sequence: MKTLKFLSAEAFVQTGPNARRNLHCLSYNLYPILFKASYLHEEASFLHDLVQTWPLTELNLRKLLGKTTDCPEDLTCSTCRLCLEAFLTGLRDYVLQASTTYAKILQVVDLIGIRDTEHQICQCRRTLGRWARTEMLTRVCYETMVSMQAGQSAPSAFNVEVDVRLDAFVTGRNYEVVSQALLLRRHCPLKLQFVGLRVDSLSLRNLFYLLKLVESHGPQKLEVVHNVHLEAPHIEVMLSQLKFPRLRSLTFPAQALNVHRLGLEDQDLMRVLGELMSKLTELRELYLGFSTLTGHLRKLLSPLNTPLECIELANCSINALDMAYFANSLHSEHLVKLDLSGHEVADLFPNTFRKLLQRCSSTLISLGLEECGLDDEKLDLLTQALTPCHGLQELKILGNPLTSAALHRLFNTLANAYPALRYVELPVPRDCYPESVTYPLDDRTLVNYDSDKFQQARTELVGILEREGKGHVEVCTPLLGVYDADINETSNELGVSMLSSFNNVIGSFIDTVNTVTQRREHRLME
What are the official names of this protein?
Leucine-rich repeat-containing protein 14B.
What is the protein family that this protein belongs to?
Belongs to the PRAME family. LRRC14 subfamily.
Protein: HOA6_RHOJR
Sequence: MTRPELRDDVRIVDTTLRDGSHAQSHQFTESQVRDTVRALDGAGVEVIEVTHGDGLGGSTFNYGFSRISDLELVQVAADTAEQAKIAVLLVPGIGTADDLRKAADRGAEVVRIATHCTEADVSLQHFEIARDLGMQTCGFLMMAHRTTPEELARQARLMVDAGCQVPYVTDSAGALLMHEAKDRFDALITEVGDDAWVGYHGHQNMSLGVANSVIAYEAGVRYIDGSLCALGAGAGNSPTELLAAIFDRMNIATGLDVMATLDAAETVVRPYLNRWPKIDRNAIVQGWVGVYSSFLLHAETAGARYGVPVHEILRRCGELGYVGGQEDMIIDVAIQLAKVSGTVSEPSASLVAG
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 6, HOA 6, 4-hydroxy-2-keto-pentanoic acid aldolase 6, 4-hydroxy-2-oxopentanoate aldolase 6.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: HEM3_HELPS
Sequence: MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFTKELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGAKVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAKYRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLERAFVKGLNGGCQIPIGVHASLMGDRVKIRAVLGLPNGKEVIAKERQGDKTKAFDLVQELLEAFLQSGAKEILEKAQLF
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: THIC_ALKMQ
Sequence: MNYTTQMDAARKGLVTKEMEAVARKEGMDIEILRERVATGKIAIPANKNHHSLDAEGIGEGLRTKINVNLGISKDCPNIEVELDKVRTALEMKAEAIMDLSSFGKTEEFRKSLIEMSPAMIGTVPIYDAVGFYDKELQDITAQEFIDVVEKHAKEGVDFVTIHAGMNQETAAVFKRNPRLTNIVSRGGSLLYAWMELNKKENPFYQYYDQLLEICEKYDVTISLGDACRPGSIHDATDASQIKELMVLGELTLRAWEKNVQVMIEGPGHMAIDEIAANMVLEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAASHGADFLCYVTPAEHLRLPTLEDMKEGIIASKIAAHAGDIAKKVPGARKWDNEMSRARQQLNWEKMFELAIDPEKARRYREESKPEHDDSCTMCGKMCSMRNMNKIMEGKNINILREDD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: YNFA_ECO8A
Sequence: MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLALFVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIVAGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLAL2_HUMAN
Sequence: MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGAHIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFTSGLSSTTLPRFHQAFQ
What is the function of this protein?
Shows weak transcriptional activatory activity.
What are the official names of this protein?
Zinc finger protein PLAGL2, Pleiomorphic adenoma-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSAB_LOBMA
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFETWIQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSALSLIGGWLHLQPKWKPRVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGEYVRWNNFLNVLPHPQGLGPLFTGQWNLYAQNPDSSSHLFGTSQGSGTAILTLLGGFHPQTQSLWLTDMAHHHLAIAILFLIAGHMYRTNFGIGHSIKDLLEAHIPPGGRLGRGHKGLYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTNGPAFNAGRSIWLPGWLSAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWKDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SCMC2_XENLA
Sequence: MARPRSLVSPLLSGVFCQCDTVSGAPHSHETPASPSLAAAALAADPCGGLLCGGPEHERRLQILFQELDVNKDGAICINDLAVGLKRLGVHRTELELRKIVKAGDKDQDGQLDFDEFVHYLRDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVNISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHSAENIPEIILYWKHSTIFDVGENLLVPDEFTVEEKQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMSILGGFTHMIREGGFRSLWRGNGINVIKIAPESAIKFMAYEQIKRIIGSNQETLGIHERFVAGSLAGVIAQSSIYPMEVLKTRMALRKTGQYQGVLDCGKKILLQEGLSAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQRYATSSADPGVFVLLACGTVSSTCGQLASYPLALVRTRMQAEASVEGAPQMTMSKLFKHIVKTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKLTLGVQSR
What is the function of this protein?
Calcium-dependent mitochondrial solute carrier.
What are the official names of this protein?
Calcium-binding mitochondrial carrier protein SCaMC-2, Small calcium-binding mitochondrial carrier protein 2, Solute carrier family 25 member 25.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TCF19_PIG
Sequence: MLPCFQLLRIGGGRGVDLYTFHPPSGAGCTYRLGCRADLCDVALRPQQEPGFISEVHAELHAERRGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGPPGTSPSEFYMFQQVRVKPQDFAAITIPRSRGEEGETRAGFRPMLPSQGAPQRPLSTLSPTPKATLILNSIGSLSKLHLQPLTFSRSGSGPQNPPVSTTPGEVRTTPSAPPPRNRRKSAHRVLAELDDEREAPESLPPVLIEPRKKLLRVEKTPPTPSGNRRGRPRKHPVSIPRAPPAAGGGEPCAAPCCCLPQEETVAWVQCDGCDTWFHVACVGCSIQAAKEADFRCPGCRVGIQS
What is the function of this protein?
Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression.
What are the official names of this protein?
Transcription factor 19, TCF-19, Transcription factor SC1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOZ_BRUMB
Sequence: MARVTVEDCVDKVENRFELVLLAGHRARQISQGAPITVDRDNDKNPVVALREIADETLSPDDLKEDLIHSLQKHVEVDEPEAAPAQIANAAEEIAEGIAEAGEEDVVTFDRMSEEELLAGIEGLVAPEKNDGF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SIX1_GORGO
Sequence: MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNSVLLLQGNMGHARSSNYSLPGLTASQPSHGLQTHQHQLQDSLLGPLTSSLVDLGS
What is the function of this protein?
Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development (By similarity).  Plays an important role in the development of several organs, including kidney, muscle and inner ear (By similarity).  Depending on context, functions as transcriptional repressor or activator (By similarity).  Lacks an activation domain, and requires interaction with EYA family members for transcription activation (By similarity).  Mediates nuclear translocation of EYA1 and EYA2 (By similarity).  Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter and CIDEA enhancer (By similarity).  Regulates the expression of numerous genes, including MYC, CCNA1, CCND1 and EZR (By similarity).  Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2 (By similarity).  Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex (By similarity).  During myogenesis, seems to act together with EYA2 and DACH2 (By similarity).  Regulates the expression of CCNA1 (By similarity).  Promotes brown adipocyte differentiation (By similarity).
What are the official names of this protein?
Homeobox protein SIX1, Sine oculis homeobox homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SIX/Sine oculis homeobox family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: FETP_MARMS
Sequence: MANTVFCKKFQKEMEALDRAPLPGAKGQEILQNVSKQAWQEWQHLQTMLINEKQLNLMQSESRKYVMEQMDKFFNNEATDKLAGYVDPDDIKEL
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: Y7456_BRADU
Sequence: MPEITVSMAEGRTDEQKAGMMRDITQALVKNLGVDADAVVIQINEAPLRHKMKGGKTFVERAAAAKK
What are the official names of this protein?
Probable tautomerase bsl7456.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: YBGF_BACSU
Sequence: MNSAHNKNETTFQRSMKSRHLFMLSLGGVIGTGLFLSSGYTIQQAGPAGTILAYLVGAGIVYLVMLCLGELSVAMPVTGAFHTYAAKYIGPGTGFTVAWLYWLTWTVALGSEFTAAGLLMQRWFPHTSVWMWSAVFALFIFLLNAFSVKFFAESEFWFSSIKVLAIVLFILLGGSAMFGIIPIKGGEAAPMLSNFTAEGGLFPNGFVPILMTMLSVNFAFSGTELIGIAAGESVDPDKTIPKAIKTTVWRLSLFFVGTIFVLSGLIPIQDAGVIKSPFVAVFDRVGVPYAADIMNFVILTAILSAANSGLYASSRMLWSLSKEKTLHPTFAKLTSKGTPFNALVFSMIGGILSLLSSVFAPDTVYVVLVSISGFAVVVVWMGIAASQFMFRKRYIEAGNKVTDLKYRTPLYPFVPIAAFLLCLASVVGIAFDPNQRIALYCGVPFMAICYAIYYVKNRKSQPAADMTHSK
What are the official names of this protein?
Uncharacterized amino acid permease YbgF.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL332_MYCTA
Sequence: MARTDIRPIVKLRSTAGTGYTYTTRKNRRNDPDRLILRKYDPILRRHVDFREER
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ISPE_SHEB9
Sequence: MPAAISRNWPAPAKLNLFLHINGRRADGYHELQTLFQFIDYCDMLDFKVTETPELILHSNMSGVVADSDNLILRAAKSLQQTTGFNGGAEIWLDKRLPMGGGLGGGSSDAATTLVALNTLWHTQLSTEELAKIGLKLGADIPVFIHGFAAFAEGVGERLQAVNPSEPWYLVIAPDAHVSTADVFQDPLLPRDTPKLAIDTLMSQPWANDCQKLVVSKYPQVAKALGWLLEYAPSRMTGTGACVFGEFTQQQQALAALAKLPSEMQGFVAQGMNLSPLITRLSHP
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MURD_STRPQ
Sequence: MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTQATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRGDA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_ECO27
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M1030_ARATH
Sequence: MQQVFRREGINLYYYSNKTKKFSLDSWYLPQLHLLESKGNKKSKAATDQYFIHPSRTRQERDLTDRKHRPEQQQLQRRVTRWKKEVTTRSRPKETSSTHLPYHGSY
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg01030, ORF106e.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GCH1L_STRP3
Sequence: MKAKTLIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLDIRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNIDIVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTVRLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAVDPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.