PharMolix/UniProtQA huggingface dataset:
Protein: ISCS_ACIB5
Sequence: MKRPIYLDYAATTPVDPQVAERMMECLTFDGTFGNAASRSHAYGWQAEEKVEYAREQVANLIKADPREIVWTSGATESDNLALKGVAQFYASKGKHIITSKIEHKAVLDPCRELEEQGFEITYLEPEPQTGLITPEMVKAALRPDTILVSLMMVNNEIGTVTDVAAIGELTRANKTFFHVDAAQAAGKVDIDLSTMKIDLMSFSAHKIYGPKGIGALYVRRSPRVRLKAQIHGGGHERGMRSGTLATHQIVGMGEAFELAGKTMHAEQERIRKLRDKLWNGLQDLEQVFLNGHPTQNVANYLNVSFNFVEGESLMMSLKDAAVSSGSACTSATLEPSYVLRALGLSDELAHSSIRFSFGKYTTEEDIDHVLTITKAAVEKLRELSPLWDMYKEGIDLSTVEWAEH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_YERPG
Sequence: MSPSEYALEVAKRRTFAIISHPDAGKTTITEKVLLFGHAIQTAGTVKGRGSSHHAKSDWMEMEKQRGISITTSVMQFPYGGCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDREIRDPMEVLDEVERELNIACSPITWPIGCGKSFKGVYHLHKDETYLYQSGKGHTIQEVRIVKGLNNPDLDVAVGEDLAKQFRQELELVQGASHEFDHEAFLSGDLTPVFFGTALGNFGVDHMLDGLVEWAPAPMPRKTDTRVVVASEEKFTGFVFKIQANMDPKHRDRVAFMRVVSGRFEKGMKLRQVRTKKDVVISDALTFMAGDRSHVEEAYAGDIIGLHNHGTIQIGDTFTQGEDMKFTGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLSNNDLIVGAVGVLQFEVVSSRLKSEYNVEAVYESVNVSTARWVECHDVKKFEEFKRKNELNLALDGGDNLSYIAPTMVNLNITQERYPDVIFRKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_LYSSC
Sequence: MISVNDFRTGLTIVVDGQLYRVLDFQHVKPGKGAAFVRSKLRNLRNGSVNDKTFRAGEKVEKAQIDNRKMQYLYAQGDEHVFMDLESYEQTELASSAIEYELKFLKENMEVHIQSYQGEMLGVELPNTVQLEVTETEPGIKGDTASGGTKPATLETGLIVQVPFFVNQGDVLIINTEEGSYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAMB_STRSD
Sequence: MRRVVGKRVQEFSDAEFEQLRSQYDDVVLDVGTGDGKHPYKVARQNPSRLVVALDADKSRMEKISAKAAAKPAKGGLPNLLYLWATAERLPPLSGVGELHVLMPWGSLLRGVLGSSPEMLRGMAAVCRPGASFLVALNLHAWRPSVPEVGEHPEPTPDSADEWLAPRYAEAGWKLADCRYLEPEEVAGLETSWTRRLHSSRDRFDVLALTGTISP
What is the function of this protein?
Specifically methylates the N(1) position of adenine 1408 in 16S rRNA.  Confers resistance to various aminoglycosides, including kanamycin, neomycin and apramycin.
What are the official names of this protein?
16S rRNA (adenine(1408)-N(1))-methyltransferase, 16S rRNA m1A1408 methyltransferase, Kanamycin-apramycin resistance methylase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Kanamycin-apramycin resistance family.
Protein: HIS8_THEVB
Sequence: MATFLRPELSNFRAYSTPTSDSLPLELDYLDTNEFPWDLPTALKEVLAQQYVSTLASHRYPDSHHWPLRQAIARYVSEQSPTEISPHQIAVGNGSDELIRSILLATAIGGYGSILVAEPTFSIYGILAQTLGIPVHRATRDPDTFAVEIAAANTLIAQAAPPVRVLFMLQPNSPTGNPLTAAEVDWLRQLPEDILVVIDEAYFEFSGKTLVGDLAAHPNWLILRTFSKAFRLAAHRVGYAIGNAEVIAVLEKVRLPYNLPTFSQVAAQVVLDHRQALLAEIPTVLAQRDRLYKWLQSCPQLHVWPSVANFLFFRLREPQHTPSLWDALRDQGTLVRAIAGGIRVTIGTPAQMERFWQRLQASLNQQKSTDN
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: CALMB_HALRO
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKETDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTCK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin-B, CaM B.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: RMLD_SINFN
Sequence: MRLAVTGKNGQIALALKAQARPDVEILTLGRPNFDLACRSTVASSIRDAAPDIIVSLAAYTAVDKAESEPYEAFAVNRDGVQALAEAAAGLGVPVIHLSTDYVFDGAKPVPYCEEDRTGPISVYGRSKLEGEFAVASANPNHTILRTSWVYSRYGQNFVKKMLRLADTNDELNVVADQLGCPTSADDISVAVMTIARRMLSSSSADLRGIFHLSGSGEASWAAFAKYVFSVYDEITGRQIKVHDISAAEYPTPARRPANSRLHCDKLERTFGIRLPNWEESTRRLVWALLLEGKDA
What is the function of this protein?
Involved in the biosynthesis of the dTDP-L-rhamnose which is an important component of lipopolysaccharide (LPS).  Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.  RmlD uses NADH and NADPH nearly equally well.
What are the official names of this protein?
dTDP-4-dehydrorhamnose reductase, dTDP-4-keto-L-rhamnose reductase, dTDP-6-deoxy-L-lyxo-4-hexulose reductase, dTDP-6-deoxy-L-mannose dehydrogenase, dTDP-L-rhamnose synthase.
What is the protein family that this protein belongs to?
Belongs to the dTDP-4-dehydrorhamnose reductase family.
Protein: HXB5_CHICK
Sequence: DMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLASAGSAFQP
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B5, Homeobox protein Hox-2.1, Ghox-2.1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACO12_RAT
Sequence: MEPTVAPGEVLMSQAIQPAHADSRGELSAGQLLKWMDTTACLAAEKHAGISCVTASMDDILFEDTARIGQIVTIRAKVTRAFSTSMEISIKVRVQDKFTGIQKLLCVAFSTFVVKPLGKEKVHLKPVLLQTEQEQVEHRLASERRKVRLQHENTFSNIMKESNWLRDPVCNEEEGTATTMATSVQSIELVLPPHANHHGNTFGGQIMAWMETVATISASRLCHGHPFLKSVDMFKFRGPSTVGDRLVFNAIVNNTFQNSVEVGVRVEAFDCREWAEGQGRHINSAFLIYNAVDDQEELITFPRIQPISKDDFRRYQGAIARRRIRLGRKYVISHKKEVPLGTQWDISKKGSISNTNVEALKNLASKSGWEITTTLEKIKIYTLEEQDAISVKVEKQVGSPARVAYHLLSDFTKRPLWDPHYISCEVIDQVSEDDQIYYITCSVVNGDKPKDFVVLVSQRKPLKDDNTYIVALMSVVLPSVPPSPQYIRSQVICAGFLIQPVDSSSCTVAYLNQMSDSILPYFAGNIGGWSKSIEEAAASCIKFIENATHDGLKSVL
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels.  Preferentially hydrolyzes acetyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A thioesterase, Acyl-CoA thioester hydrolase 12, Acyl-coenzyme A thioesterase 12, Acyl-CoA thioesterase 12, Cytoplasmic acetyl-CoA hydrolase 1, CACH-1, rACH, rCACH-1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MXIH_SHIFL
Sequence: MSVTVPNDDWTLSSLSETFDDGTQTLQGELTLALDKLAKNPSNPQLLAEYQSKLSEYTLYRNAQSNTVKVIKDVDAAIIQNFR
What is the function of this protein?
Necessary for the secretion of IPA invasins.
What are the official names of this protein?
Protein MxiH.
What is the protein family that this protein belongs to?
Belongs to the MxiH/PrgI/YscF family.
Protein: H18E1_CYRHA
Sequence: MKLSIIIIATSLVIAVVAFPSKDSKAIENDKTEQRMEIVVQETARACSKQIGNKCKRNCECCGKTVVCGTIYVGGKEVNQCMDKTSDNAILNGLGKGMNFIENTFSFCV
What is the function of this protein?
Putative ion channel inhibitor.
What are the official names of this protein?
Hainantoxin-XVIII-5, HNTX-XVIII-5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 25 family. F7 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMN_DESVH
Sequence: MTDILNLTYEELEAFMTAELGEPRFRARQVWQWLWQKCARSFDEMTNVSKATRARLAEKAVITWPEVETVQKSADGTTKFLLRLADGALVETVLIPSASREGTLRITQCLSCQVGCAMGCTFCSTGTMGFERNMTMGEILGQVLVARAHLGDSRPDHPILRNLVFMGMGEPLLNLNEVMRSLRTLNDEFGLSFSPRRITVSTCGIEKGLRELGESGLAFLAVSLHAPNQEIRKRIMPKAAHWHLDDLITALESYPLKTRERVTFEYLLLGGVNDGIEHARELVRLVSRTKGKLNLIVYNPAEGDPYDAPTPERILAFEQYLWSKNITAIIRKSKGQDIKAACGQLKASELQRGTASAGADAPEA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_SALPB
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGNVEWFAAPRRLALKVANLAESQPDREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLKTDKGEWLLYRAHVKGESTEALVPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPQILLERGKVIADYEARKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPTQIISGNEKVVRPRLADAEFFFNTDRKKRLEDHLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAGQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLALDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEEASALAAANKRVSNILAKATEPLNDIVHASVLKEAAEIELARHLVVLRDKLQPYFADGRYQEALIELAALRAPVDEFFENVMVNAEEKDIRINRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_SALHS
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVGQIKTRLGANPVPLQLAIGAEEGFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMQDLANEWHQNLIESAAEASEELMEKYLGGEELTEEEIKQALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKTARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPENPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYREAIRAKVTDIEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKSGPLAGYPVVDLGVRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDDAPNNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_CHLAB
Sequence: MFKKFKPVTPGTRQLVLPAFDELTTQGELSGKKTRKSVRPNKKLSFFKKSSGGRDNLGHISCRHRGGGAKRLYRVIDFKRNKDGIEAKVVSVEYDPNRSAYIALLSYADGEKRYILAPKGIKRGDQVISGEGSPFKLGCCMTLKSMPLGSTVHNIEMRPHSGGKLVRSAGLAAQVIAKTPGYVTLKMPSGEFRMLNEGCRATIGEVSNSDHNLCVDGKAGRKRWKGIRPTVRGTAMNPVDHPHGGGEGRHNGYIPRTPWGKVTKGLKTRDKRKSNKWIVKDRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TBPB_HALSA
Sequence: MSTLADTIHIENVVASSDLGQELALDQLSTDLPGAEYNPEDFPGVVYRLQEPKSATLIFRSGKVVCTGAKSVDDVHEALGIVFGDIRELGIDVTSNPPIEVQNIVSSASLEQSLNLNAIAIGLGLEQIEYEPEQFPGLVYRLDDPDVVVLLFGSGKLVITGGQNPDEAEQALAHVQDRLTELGLLD
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
What are the official names of this protein?
TATA-box-binding protein B, Box A-binding protein B, BAP B, TATA sequence-binding protein B, TBP B, TATA-box factor B.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: CYAA_STRCO
Sequence: MTVDDTGSGADGDGRVDPEPAPDSADPGEDPLALRLEGLILGAERRYTPFQAARSAGVSMELASRFWRAMGFADIGQAKALTEADVLALRRLAGLVEAGLLSEAMAVQVARSTGQTTARLAEWQIDSFLEGLTEPPEPGMTRTEVTYPIVELLLPELQEFLVYVWRRQLAASAGRVIQAGDDEEMVDRRLAVGFADLVGFTRLTRRMEEEELGELVEAFETTSADLVAARGGRLVKTLGDEVLYAADDAGTAAEIALLLVETMAHDETMPELRVGIAFGTVTTRMGDVFGTTVNLASRLTSIAPKDAVLVDTAFAEELIRTRDAPASEAAAAEEAAAAEKEGEEPPVYRFALQPMWQRPVRGLGVVEPWLLTRRDGGGGEA
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
Protein: RS10_ANAMF
Sequence: MVTQKIYIELKAFDHCLLDGSARNIILIARRSGAKVNGPVFFPRRIAKFIVNRSTHVDKKSREQFEIRTHKRLISLPKANSAILQALMSLQLPAGVDVKVKVVGG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RPOB_HAES1
Sequence: MVYSYTEKKRIRKSFGKRPQVLNVPYLLTIQLDSFDKFIQRDPDGQQGLEAAFRSIFPIVSNNGNTELQYVSYQLGEPVFDVRECQIRGTTYAASLRVKLRLVSYDKDAASGTIKDIKEQEVYMGEIPLMTSNGTFVINGTERVVVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLYARIDRRRKLPATIILRALNYTTEEILDLFFDKVSFEIKDNKLLMTLVPERLRGETASFDIEANGKVYIERGRRITARHIKALEKDKITQVEVPTEYIVGKVSAKDYVDLTTGEIICPANMEISLELLEKLSQAGYKNIETLFTNDLDFGPYISETLRVDPSYDRLSALVEIYRMMRPGEPPTKEAAEGLFDNLFFSSERYDLSAVGRMKFNRSLGIEDTTGSGTLSKEDIVNVMRKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLESVTPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHATHYGRVCPIETPEGPNIGLINSLSVYARTNDYGFLETPYRKVVNGQVTEEIEYLSAIEEGKYVIAQANSNLDGELRFTDAFVTCRGEHGESGLYRPEEIHYMDVSTQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPVALDSGVAVVAKRGGTIQYVDASRIVVKVNEDETIAGEAGIDIYNLIKYTRSNQNTCINQIPCVQLGEPIERGEILADGPSTDLGELALGQNMRVAFMPWNGYNFEDSMLVSERVVQEDRFTTIHIQELSCVARDTKLGSEEITADIPNVGEAALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLVEELEILEAGLFARVRNLLLSGGFNDKQLENLDRTQWLEQTLVDEDKQNQLEQLAEQYEELRKDFEHKLEIKRSKIIQGDDLAPGVLKVVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVDIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINAMIKQKQDVEKLRGYIQKAYDLGDGSQKVDLSTFTDEEVLRLAKNLRKGMPLATPVFDGAHEKEIKALLELGGLPTSGQITLFDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVGGTHQMDPGTPESFNVIMKEIRSLGINIDLDEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: GRPE_HELPY
Sequence: MKDEHNQEHDHLSQKEPEFCEKACKEQQYEEKQEAGEKEGEIKEDFELKYKEMHEKYLRVHADFENVKKRLERDKSMALEYAYEKIALDLLPVIDALLGAHKSAAEEDKESALTKGLELTMEKLHEVLARHGIEGIECLEEFDPHFHNAIMQVKSEEKENGKIVQVLQQGYKYKGRVLRPAMVSIAKND
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y106_RICPR
Sequence: MQSNLLKVLGVLAIVATLVCFIFAALGMIGAVRVGNGCYMRYSKDGNGSTDSITSTITLNANANYVNISKMLPDGTTKLIPDPNRYGEWLNTQVLVEKNQSVNLQVVGQVSLCLAYLPKNNLQFTERTRPGKSNLDDSGQMIPIPRVQDANSPPISLIMDAKNNEWRNIAELYANDKVLVSVSPNFANTDATVDDVFKGVKVTKDCTQGKTSYYPICGKYSIYSGKYVTACELKQNYWKGNVHREECYCVFGCIYKEDSDPWVCDMANAASHCCTSLVCDSLPAWINHYSNMPEAYKDDGSFTFSWSDKSKNLLIEYEDLQCSNNVNIPPNGQCPDIVNNRSPKDKNYIGGVSCTSGICKDGDFQKNRKFWYTADGKGGKGPTGLIYQMNDIGSVSQALPSKLEFAKFVPETEQPPEYKDKNGKYLYKVIYNIPFNSNIEKSYLQYRLWSPTSQDASKNTGGYVLNIKQTKCYRENGNSFKDIFDDRGRVQYIIVKSSENPNTSGKTYSPQGINVDSDGKSHFNANESGYIWMKILNDPSNNLKDYKDSEGSYKVHFSTSLKVGSFTIKVMNPLLQLFKTKVQDAATSIFKNMVCYKATDNSSCTNFFTYIKAILILYVMTYGAMFLLGFAKINQKELVIRIAKIGVVSGLINGNTFEFFNNYLFDAITNFSDSIIANMSGYSLFTSTNTISNPFMFLDAIMSKIFFSQTFIAQLLSLLSLGLSGIIYFIITFIAICIVIITTLRAIAVYIMAFMATCILIGIAPLFISFLLFDFTRYLFDNWVRFTIRYMIEPVVMMAGIIVLTQLFTIYLDFVLGYSVCWKCTLPIKIPFIGTILPIALLNVPIFCINWFAPWGMDYMSGMMGVNMQNIVALVIIAYGMYGYVEFSGRMVAKLTSAAGPSATQIGGRMSHDAGQKVLSQIGMDYRTRQGITGRAKSRLEQRNRTLEHAEQNSKKYKKRIGENTNEETLK
What are the official names of this protein?
Uncharacterized protein RP106.
What is the protein family that this protein belongs to?
Belongs to the TrbL/VirB6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1317_METJA
Sequence: MVRKVAEQNLQKNNENDRELSKNVYLLGFTSFLNDMSSEMIMPILPMLITSVGGGSLSIGLVGGLREFISNILMVLIGYCSDKVRKRKIFVVLGYLTSSMFKLLLGLSKSWLGAVIFSSLERMGKGIRTAPRDAIISESMPKTLGKGFGIQRAFDTAGAILGSTLSLLFILYLQYSFNQIILIAAVIGFLTLIPLYFVKEKPSPSNNKITFRVGIKNLPKELKLFILISAIFTLSNFSYMFYILRAQEFLMIVDEKMAIIIPIALYILYNIFYATFSIPFGILSDKIGRKSVLTIGYIVYGIVSLGFAYFISQKSLILLFALYGIAYALFAGNQKAYVSDLSSEDIRATALGLFYTVVGLTSLPASLIAGYLWKISPEMTFLYGSVLAIISGLLLLFI
What are the official names of this protein?
Uncharacterized MFS-type transporter MJ1317.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TPIS_ARCFU
Sequence: MRKMGVVIINFKAYKEGFGKRALELAKIAENVASRCDEYVGIAVSFLDLPVIAREVSIDVYAQHVDAVGFGSHTGRINADMIAEYGAKGSLVNHSERRLKLADIEFNVSRLRELGLTSVVCTNNVPTTAAAAALNPDFVAVEPPELIGSGIPVSKAEPEVVENSVKAAKEVNKSVRVLCGAGITTHEDYVKALELGAEGVLLASGVVKAEDQKRALEELVGLL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_LEGPC
Sequence: MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFRYTRQYKAENGQSGMGGNCTGKKGEDLTIKVPVGTMVYDADTGELLADISQPGVPVLIAQGGFHGLGNTRYKSSVNRSPRQTTPGSSGESRNLRLELRVLADVGLLGLPNAGKSTLIRAVSSSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCVLLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDEKEREEKIQSIIKGLEWKDKVFSISAIETKGTQELCYALMQLIDEMKESEA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA_STRAW
Sequence: MSTPFYVSPQQAMADRAEYARKGIARGRSLVVLQFADGIVFVGENPSRALHKFSEIYDRIGFAAAGKYNEYENLRIGGVRYADLRGYTYDRDDVTARGLANVYAQTLGTIFSSAAEKPYEVELVVAEVGETPEGDQIYRLPHDGSIVDEHGSVAVGGNAEQISTYLDQRHQDGMTLAEALKLAVQSLSRDTNGSEREIPAERLEVAVLDRTRPQQRKFKRIVGRELSRLLEAAGASTAGEAGSAEDEGSDDEK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAM_GUITH
Sequence: MISDTQIFVALILALFSFVLAIRLGTSLY
What are the official names of this protein?
Photosystem I reaction center subunit XII, PSI-M.
What is the protein family that this protein belongs to?
Belongs to the PsaM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TWF1_YEAST
Sequence: MSTQSGIVAEQALLHSLNENLSADGIVIIIAKISPDSTSVHQTQVARSFEELVQLASQEREPLYIFYKPEGLDKYFFVSFIPDGSPVRSRMLYASTKNTLARQVGSNSLSTEQPLITDAQDLVDLKNFDSARPAGQNKPLTHDEEMQIEINKQQALLRKNTSVKLVSQDSASPLSLTFRVNSEKPINEILDSEGKNLIIFQIDPSNETIQIVQSDTCPSVDELYIDLPGPSYTIFRQGDSSFFIYSCPSGSKVKDRMIYASNKNGFINYLKNDQKIAFSKVVEIGDFVELDKSLLMATNKEDSLDHGSNPDLPNKSNLKFNKPKGPLRKRRT
What is the function of this protein?
Actin-binding protein involved in motile and morphological processes.  Inhibits actin polymerization, likely by sequestering G-actin.  Prevents actin filament assembly by forming a 1:1 complex with actin monomers, and inhibits the nucleotide exchange reaction of actin monomers (By similarity).
What are the official names of this protein?
Twinfilin-1, Twinfilin-A.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.