PharMolix/UniProtQA huggingface dataset:
Protein: CCD13_HUMAN
Sequence: MAADESSQNTLRLQFKAMQEMQHKRLQKQMEKKREKELSLKSRADDQEEPLEVSDGLSLLHAGEPNSKNSFEKRVLEDEIEHLRNELRETVDENGRLYKLLKERDFEIKHLKKKIEEDRFAFTGTAGVAGDVVATKIVELSKKNRLLMAESEGAKTRVKQLTNRIQELERELQTALTRLSAKGATDAGAKPPRAQMGDRALLETPEVKALQDRLVATNLKMSDLRNQIQSVKQELRMAQKVLAREVGEDINVQQLLSSPGTWRGRAQQILVLQSKVQELEKQLGQARSQSAGTASDELSVYPDPRKLSAQEKNLLRIRSLEREKQEGLEKLASERDVLQRELEELKKKFEGMRSRNKLLSSEMKTLKSQMGTLVEKGRHDDELIDALMDQLKQLQEILGSLSLQEEKTRVSQHHLDQQLNSEAQRSNSLVAQLQAMVAEREAKVRQLEMEIGQLNVHYLRNKGVGEGSSGREVSPAYTQFLEDPGLTKSPASAGDHVGRLGSSRSVTSLGHTLVESALTRPSLPSPHRTSPRFSDSPEQKGWQAQVSEIKALWQAAEVERDRLTEFVTVLQKRVEESNSKLLESERKLQEERHRTVVLEQHLEKIRLEPGKASASQRAAPRTKTGLPTSNNRHNPTGSEKKDPSFAQLSDVPVESQMEELTTRLAIQVEENEMLKAALGSALRGKEEDFRMYHEILGQVKSVFLQALRQQKTGKQ
What is the function of this protein?
Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia.
What are the official names of this protein?
Coiled-coil domain-containing protein 13.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body.
Protein: LPPA_MYCTO
Sequence: MIAPQPISRTLPRWQRIVALTMIGISTALIGGCTMDHNPDTSRRLTGEQKIQLIDSMRNKGSYEAARERLTATARIIADRVSAAIPGQTWKFDDDPNIQQSDRNGALCDKLTADIARRPIANSVMFGATFSAEDFKIAANIVREEAAKYGATTESSLFNESAKRDYDVQGNGYEFRLLQIKFATLNITGDCFLLQKVLDLPAGQLPPEPPIWPTTSTPH
What are the official names of this protein?
Putative lipoprotein LppA.
What is the protein family that this protein belongs to?
Belongs to the mycobacteriales LppA/LppB family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RMP_MOUSE
Sequence: MEPPSEPEPEPQPLAEASAAAPLRAPEVARLREEQEKVVTNCQEKIQHWEKVDNDYSALQERLRTLPDKLSYDVMVPFGPLAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDFKKVLKNFESRVEFTEDLQKMSDAAGDFVDIREEIKSDFEFKGKQRIAHKPHSKPKTSDIFEADFENGVKPKNTFDADELWARLEELERQEELLGELESKPDTVIANGEDRVSSEEEKEGADTGVNVVSPVTDSSAASSCKRRAGNAGLPNGQVNSLNYSVNGSNSYHSNKDDDEEEEDDDDDDDEDDDNESDHAISADNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKSGAGSHATHELPAIKSPADIYRVFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAADVEDRRGLLRSTSSEEAVATEAGGSSLDELQENHPKKPLPSGVSEAFSGTVIEKEFLSPSLAPYSAIAHHALPTIPERKEVPSEVSEEPTKRVSKFRAARLQQRS
What is the function of this protein?
Plays a central role in maintaining S6K1 signaling and BAD phosphorylation under normal growth conditions thereby protecting cells from potential deleterious effects of sustained S6K1 signaling.  The URI1-PPP1CC complex acts as a central component of a negative feedback mechanism that counteracts excessive S6K1 survival signaling to BAD in response to growth factors.  Mediates inhibition of PPP1CC phosphatase activity in mitochondria.  Coordinates the regulation of nutrient-sensitive gene expression availability in a mTOR-dependent manner.  Seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs and proteins with roles in transcription and ubiquitination (By similarity).
What are the official names of this protein?
Unconventional prefoldin RPB5 interactor, Protein NNX3, Protein phosphatase 1 regulatory subunit 19, RNA polymerase II subunit 5-mediating protein, RPB5-mediating protein.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase II subunit 5-mediating protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion. Cell projection, dendrite. Note=Colocalizes with PFDN2, PFDN4, PPP1CC, RPS6KB1 and STAP1 in mitochondrion.
Protein: DSBB2_PSEE4
Sequence: MSLACLRSFFLPALLASTAVLVASFHLESVVGLVPCALCFSQRLMLGVYALVCLAALVHSPAARGRRAYAGLALASAFGGALLAGRHVWLQGDPQVVDGCHLPVEQVLQRPLGEILQMFLLGSPDCVSISWSFLDLTLPEWSLLAFLLLAAMPLSWLVAYRFRKRAMA
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B 2, Disulfide oxidoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ULAA_ECOLI
Sequence: MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKGTIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIDRMGDAYSWVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTIICTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVEDLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVHWTVYILQTGFSFAVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGTIGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEIFGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRALRAEEDAEKQLAEQSA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIC component, Ascorbate-specific permease IIC component UlaA.
What is the protein family that this protein belongs to?
Belongs to the UlaA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SKT_MOUSE
Sequence: MEESEGQKCEPNLPPSGDSRQMPQQGRSNLHVTSQEDAACRRPRERLSNGNARAQVSKPARNIPRRHTLGGPRSSKEILGMQPSEMDRKREAFLEHLKQKYPHHATAIMGHQERLRDQTKSPKLSHSPQPPNLGDPVEHLSETSGDSLEAMSEGEVPSPFARGSRTRASLPVVRSANQTKERSLGVLYLQYGDETKQLRMPNEVTSTDTIRALFVSAFPQQLTMKMLESPSVAIYIKDDSRNVYYELNDVRNIQDRSLLKVYNKDPSHAFNHMTKAVNGDMRMQREIVYARGDGLVAPRPGSVAHPPHVIPNSPPSTPVPHSLPPSPSRIPYGGSRPMAIPGNATIPRDRLSSLPVSRSISPSPSAILERRDVKPDEDMSSKNLVMFRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHVIAYHRTAIRSASAYCSPSLQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVGDLRMIDLHPHLNTHGPPHTLQPDRASPSRQSFKKEPGTLVYIEKPRNTSGLSSLVDLGPPLVEKQGFAYSTTTIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSSSKEASSEKMVKATANRNQADGAGTAHVSAGKVLGSVEFSLPPSQPLPAGTSPIHTSLLDMRRNVAELRLQLQQMRQLQLQNQEILRAMMKKAELEISNKVKETMKRLEDPVQRQRTLVEQERQKYLHEEERIVKKLCELEDFVEDLKKDSSSTGRVVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAVLRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDASQAAQYVAMEKATAAEVLKHQEETAHAPGQPLHCSTGSPGDVKSEVVPLSTMTVHHVQSSPVVMQPSQHSSALMNPAQNLPGGTRPHTASPPAITQEVTSAQSAPGPQSPQTPVNGSSMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLEHYNGKEFEKLLEEAQANIMKSIPNLEMPPASSPVSKGDAAGDKLELSEDSPNSEQELDKIGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRSMSKVSSEDPGPTPQTRATKCPPEEPASAWAPSPPPVPAPSSKEEEEEEEEGDKIMAELQAFQKCSFMDVNPNSHAEQSRANSHLKDTRAGATAPPKEKKNLEFYHEDVRKSDVECENGPQVESQKVTAGALRPSGPPKWERVMVDSISDTSRTSECRADTFTEENATPNKSLFRDSRNYSQKNVPKVSFSSSGLNSLEGEINKGPNVSGLQCAIPDLENQKLNFGKTKEIGQQGQENADKSHIPLPTRSAEFSIHDVKTQDQDVPVTGYGQVVLRSKVGRHANMNMNEDGESTPSSPSEEHTATDNIAFMITKTAVQVLSSGEVHDIVSQKGQDVQTVNIDGRKETASQHEGTEGEEPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECDEELERMLTEEKIEEEEEDENEDSGVRTSSQMSCEQVDSRSDRMGQKAETQSQPHVLSAELLTPGVQGVRKAEQRKLSSADSPDSGNKCGMVDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEITRSQPEDALKTMARRQEQLSPEGTLPASRTDEIRKSTYRTLDSLEQTIKQLENTISEMSPRALVDTSCSSNRDCGASLPHMAQEVSPRSLLVLDEVPPAPEPPTSISPASRKGSSTTPQTSRMPVPMTSKNRPGSLDKASKQSKLQDPRQYRQANGSAKKAGGDCKPTSPSLPASKIPALSPSSGKSSSLPSASGDSSNLPNAPATKPSIASTPLSPQAGRSAHSASLIPSVSNGSLKFQSPPHAGKGHHHLSFALQTQNGRAAPTTSSSSSPPSPASPTSLNQGARGIRTIHTPSLASYKAQNGSSSKATPSTAKETS
What is the function of this protein?
Required for normal development of intervertebral disks.
What are the official names of this protein?
Sickle tail protein, Enhancer trap locus 4.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RH36_ORYSJ
Sequence: MEVDGEARPFLLFSKPKSSKKKPKQEAEPQVHTQPEEPPNPSPSPAIEPDLRDSDEAPAAAVTEHAGDDAAAAAVPSTFAELGLSQWLVDVCDSLGMRVPTAVQRRCIPRALEGRDVLGIAETGSGKTAAFALPILHRLGEDPYGVAALALAPTRELAAQLAEQFRALGAPLGLRCLAAIGGFDSLGQAKGLARRPHVVVATPGRIATLINDDPDLAKVFARTKFLVLDEADRVLDINFEEDLRVIFGSLPKKRQTFLFSATISDNLRSLLELSGNNSYFFEAYEGFKTVDTLKQLYIHVPPDAKELYLFYLLSKMNEDNIRSVIVFVSTCRTCQYLDFLLEELGHPAVSLHSHKPQSRRLAALHNFKSSKVPVLLATDVASRGLDIQTVDLVINYDVPRYPRDYIHRVGRTARATRGGLSISFITTQRDIRLLHEIEDVVGKQLGAYDGEMRDVNKDATKVFKARRLANMKMADEGHEDKVQARKEQKKRAQERKRKHDE
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 36.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
Protein: KR193_HUMAN
Sequence: MSYYGSYYGGLGYGCGGFGGLGYGYGCGCGSFRRLGSGCGYGGYGYGSGFGGYGYGSGFGGYGYGCYRPSYYGGYGFSGFY
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 19-3, GTHRP, Glycine/tyrosine-rich protein.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 19 family.
Protein: RL10_METJA
Sequence: METKVKAHVAPWKIEEVKTLKGLIKSKPVVAIVDMMDVPAPQLQEIRDKIRDKVKLRMSRNTLIIRALKEAAEELNNPKLAELANYVERGAAILVTDMNPFKLYKLLEENKSPAPVRGGQIAPCDIKVEKGSTGMPPGPFLGELKSVGIPAAIEKGKIAIKEDKVVVKKGEVVSPKLAAVLDRLGIKPIKVGLNILAVYEDGIIYTPDVLKVDEEKLLADIQAAYQNAFNLAFNTAYPAKEVLPFLIQKAFINARALSVETAFVTKETAGDILAKAQAQALALASKLPDEALDEDIKAKLSSVEVSAAPAAEEEKEEEKKEEEKKEEDTGAAGLALLF
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog, MjaL10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: DDL_ALIF1
Sequence: MTHILLLCGGGGTEHEVSLVSSKYISQQLSELDAFEITHLEIKDEGWFHIESGLKYELRSDKTLLSGETVSSPVDYVVPCIHGYPGETGDIQSMLDMLSIPYLGCDAESSTNSFNKITSKLWYDALGIPNTPYLFLTENNEETHQSALAAFKQWGGLFVKAACQGSSVGCYKVTSEAELSKAINDAFGYSQQVLVEKAVKPRELEVAAYEIDGQLFTTAPGEVTAPDGAFYTYDEKYGSGSHSTTSLDAQNLTEEQVKLIDQYSRKVFTQMKLKDLSRIDFFLTDDNEIYLNEVNTFPGMTPISMFPKLLEHNGDCFKTFLQKAVLNAIK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GHRB_YERE8
Sequence: MKPSIVLYKSIPADLHQRLEQHFTVNSFEGLSSDNQPELLSALQQAEGLIGSGGKIDQAFLERAPKLRAASTISVGYDNFDVDALSQRGIALMHTPTVLTETVADTMMALVLSSARRVVELAERVKAGEWQDSIGDDWFGVDVHHKTIGILGMGRIGMALAQRAHFGFSMPVLYTSRRPHEAAEKRFGARRCSLDTLLAEVDFLCITLPMTEQTYHMIGPEQLAKMKSSAILINAGRGPVVDEQALIAALQDGTIHAAGLDVFAQEPLPVESPLLKLPNVVAVPHIGSATHETRYNMAACAVDNLIAALTGTVTENCVNPQVLQQA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_PROM2
Sequence: MNSQIKTKAVYWGTGRRKTSVARVRLIPGNGLITINGRSGDDYLNFNPLHLNSVKAPLQTLGLENSYDILVNVFGGGLTGQADAIKQGAARALCELSPDNRKPLKTEGHLSRDPRAKERRKYGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CLPP_AERS4
Sequence: MYKNYNDVTESPRNALIPMVVEQTAKGERSYDIYSRLLKERVIFLTGQVEDHMANLVVAQLLFLESENPDQDISIYINSPGGAVTAGMSIYDTMQFIKPDVSTVCMGQACSMGAFLLAGGAKGKRFCLPSARVMIHQPLGGFQGQASDIQIHAQEILKIKNTLNERLAFHTGQEMATIERDTDRDNFMSADQAVAYGLVDGILSQRG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_BACAA
Sequence: MQQLIAEITKGQLKTDLPSFRPGDTLRVHVKVVEGTRERIQLFEGVVIKRRGGGISETFTVRKISYGVGVERTFPVHTPRIAKIEVLRRGKVRRAKLYYLRNLRGKKARIKEIR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PHBS_MYCTU
Sequence: MTECFLSDQEIRKLNRDLRILIAANGTLTRVLNIVADDEVIVQIVKQRIHDVSPKLSEFEQLGQVGVGRVLQRYIILKGRNSEHLFVAAESLIAIDRLPAAIITRLTQTNDPLGEVMAASHIETFKEEAKVWVGDLPGWLALHGYQNSRKRAVARRYRVISGGQPIMVVTEHFLRSVFRDAPHEEPDRWQFSNAITLAR
What is the function of this protein?
Removes the pyruvyl group from chorismate to provide 4-hydroxybenzoate (4HB).  Involved in the synthesis of glycosylated p-hydroxybenzoic acid methyl esters (p-HBADs) and phenolic glycolipids (PGL) that play important roles in the pathogenesis of mycobacterial infections.
What are the official names of this protein?
Chorismate pyruvate-lyase, 4-HB synthase, p-hydroxybenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the chorismate pyruvate-lyase type 2 family.
Protein: PDXT_FRATH
Sequence: MTQKVGVLAIQGGYQKHADMFKSLGVEVKLVKFNNDFDSIDRLVIPGGESTTLLNLLNKHQIFDKLYNFCSSKPVFGTCAGSIILSKGEGYLNLLDLEVQRNAYGRQVDSFVADISFNDKNITGVFIRAPKFIVVGNQVDILSKYQNSPVLLRQANILVSSFHPELTQDPTVHEYFLAM
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SECA_DESHY
Sequence: MGFLNKLFDDNAREVKKYQKKIAAINDLEPEIKALSDEQLRAKTDEFKQRLENGESLDSLLPEAFAVVREASWRVNGQRHYDVQLIGGMVLHDGRIAEMRTGEGKTLVATLPSYLNALTGRGVHIVTVNDYLARRDSEMMGRIHQFLGLSVGLIVHGLNYAQRRESYAADITYGTNNEFGFDYLRDNMVTRPDGLVQRELHYAIVDEVDSILIDEARTPLIISGEADKPTELYNRIAMIIPRLKPEEDYNVNEKDRVVTLTEQGVSRVETMLSVENLFDDLHTELAHHVNQGLKAHALFKLDRDYVVKDGQVIIVDEFTGRLMFGRRYSEGLHQAIEAKEKVKIEKESQTLATITFQNYFRMFEKLAGMTGTAMTEEPEFKKIYKLDVVEIPTNMPMIREDLPDVVYRTEEGKFKAVVEEIIERHKKGQPVLVGTVSVEKSERLSSMLERRGIPHQVLNAKFHEKEAEIIAGAGLKGMVTIATNMAGRGTDIILGEEVAPLGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSQFFLSLEDDLMRLFGADNITGMMDKLGMDDSVPITSKMISRSVETAQRRVENRNFEIRKHVLDYDDVMNLQREVIYAQRRQVLMGGNIQESIADMLEKVVRETVDMFGAQSPYPEEWDLNSFLEYVENVFLPNHDITAEQVGSMEKEEIVEMLLERAQAHYKTRETAFGEEIMREIERAVMLQVVDKKWMDHLDAMDMLREGIGLRAYGQKNPLVEYRREAYDMFQGMISSIQEDTIRYIMRVTPQVTEQKPEEPQHVRTNRDEEQPARPVHNEGPQIGRNDPCPCGSGKKYKKCCGADS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: EFP_ESCF3
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_DEIGD
Sequence: MSLTDQKPRIERFGEITEVIPLPNLTEVQVNSFKAFLQADKAPDERDDTGLQSAFREVFPIDETEKGRSTGLVLDFLEYRLGEPPYTPEECREKDLTYQAPLYAKLQLIHKDSGLIKEDQVFLGDLPLMTDDGSFVINGADRVVISQIHRSPGVYFTSSYKGIKKMYTAAIIPMPKRGPWIELEFNGGVLEMKVNKRKFPVSLLLRVLGYDDAQLKALFTEFDPAAELPEDKSAGMNPDEALLRLFTVLRPGDPPKRDKAIQYLYGLLADPKRYDLGEPGRFKMNTKLGTRRQDRTLLTFEDGRFGDAGLVDTIRYLMALQQGLETVTMGADEDGVAIEVPVTEDDIDHLGNRRVRTVGELLADQLRVGMGRMARGVRERMLLGNPDAATPTKLVNNRPIVAAMREFFGRSQLSQFKDQTNPLSDLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPIETPEGANIGLISSLSSYAKVNDLGFIEAPYRRVVDGRVTDDVVYMTADIEDRYVIAQANSPLNPDGTFAEERVLARKKGDPMLYAPTEVDFMDVSPKQIVSINTSLIPFLEHDDANRALMGSNMQSQAVPLVRADSPAVGTGVEERVVTDSGTSVISDVTGRVTYVDARAIQVTLTEDAPQIGLVKGNVRTFELVRFTRSNQGTNLDQHPIVSVGDEVVPGQVIADGPASDQGRLALGQNITIAIMPFDGFNFEDAICISEGLVRKDFYTSVHIEKDEIEARDTKLGPEKITRDIPGLSEAALRDLDEDGIVRVGAEVKPGDILVGKTSFKGESEPTPEERLLRSIFGEKAREVKDTSLRVQSGQGGIVVKTVRFRRGDEGVDLKPGVREMVRVYVAQKRQLQVGDKVANRHGNKGVVSKILPPEDMPYLEDGTPVDLVFNPLGVPSRMNLGQILETHLGEVARLTGQKFVTPVFDSATEEAIKEMLEVAAAERLQRRKDEGFELDKREQEVLDRAGKLGVISPPNGDYAAAQMQLARTGKSVLYDGRTGEPISGPVVVGTMYVMKLYHMVEDKLHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTIKSDDIDGRDAAYQSIVKGEEVSGSTIPESFKVLVKELHSLGLDVEVLDNNDKPVDIFEGMMPKR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PBPA_CLOTE
Sequence: MANVRKRRKKKNEHKALRLTFITLLMVFLFSCVAAAGVGLAMIKAAPPLDVDKVLNPSEPSVIYDDKNKLVDTVISDTYRTIVSYEDVPDNLKNAFISIEDERFFNHRGIDYKRVFGAFFRNISNKLKGKSALQGASTITQQLVRNTLLSQEVRIKRKVQEMYLSIQLEKKVSKEQILEAYMNTIPLGGSAYGIEAASKQYFGKSVKDLNLIESAFIAGLPQSPSTFYNAAMSQKNTERYINRTKLVLGKMREHNYISKEDFDKSMAYIDKNKIPLKTSNINISRLNYEWFSREIIKQVKKDLMNEYKISPTEADKTIMYGGLKIYGTMDKSLQDFSQNTLDNLDGILGINSKDYSGIIQPEASVSIVDYKTGNVKVLIGGRGKQPPLSFNRATEFYRAPGSTIKPLTVYGPAIDTKTSTAASSYNDAPVPEEIGKLYDKEPYNPKNSPNIYEGKMTLREALMKSKNVISVRIEHELGLKTGAEYGKKFGLTIDDSMDGTSMAALSLGQLSAKTGVSGTNTLGMAAAYGVFGNKGALSKPVVYKKVVDRTGKVLLENKYASSKVMSPEAAYILYDLLKGPVSYTPGATGMKANFGPMARGKTGTSNQSSDLWFAGLSPYYSAAVWIGKDDYSPFTNEFGRYIGSSDAALIWKLIMGEAHKNLEYKTIEKPAGVTEAYVCSKSGKIPSSSCPRDSIKLEYFIEGTIPGEICDYHTGIFNNNKDKDDDDDDKDKDKEDEEENKDEKNEDKKEAKDNTKNKDKDKKKDNDRKIDMDKKPDSSKRKRKMIKPQI
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan from the lipid intermediates.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
What are the official names of this protein?
Penicillin-binding protein 1A, PBP1a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: CAIA_ECOL5
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDCLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODF_RICBR
Sequence: MTYCDKSNQTSYPFVLPNLPYEKESFKPHFTAETFEYHHGKHHNAYVQNLNNLLKDKEELQKKNLEEIIDWSSQNQNIAIFNNAAQVWNHTFFWHSIKPNGGGKPSGKILKQINEDFGSFEEFCEQFKAEATGQFGSGWAWLVYHNNRLQIVKTANAGTPIANGMQPLLACDVWEHAYYIDYRNKRPDYVDIFIKHMINWEFVENNLTK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: PSMD1_CAEEL
Sequence: MLTLLNRWRSQPGGASNAAAFIRVLESPKSAVTDKVLVLKAFNDWDVLVNTWFEVADALPAVEQLLDNNTFPEHSSAALLVSKVYFCLEQYERALEFALRGDFNVVPATRTGLGNDAEYVNKIIETAIDTYKTLSKQGSGIPQKLRDLIDRIVARNLDKREIWFVISLGFETTNLAMIDRAISAMPADLTIKNQTTLVETLNRVVNGAFDRSFRFQVIDTVIKTYLKCPSPDMSKICECYVLTDNAEAAADTITSLIAKSLSTRAYQIAFDLYETASQGFLDRVLKRFQQQDARDEKSMEKIHSILKGHETVKAYLDFFVRHNHTDSVLMEEIKENIRTASAHNALLISNGLMQYGTTCDDFLRNNLNWVSKATNWNKFNAVASLGLIHHGQESSAMKVLEPYLPKESVEGFGFKEGGAMLAYGLIHAKHGDATAMSTLAQWLKTAENEPVRHGACLGFGVAGLGSSSVSNYEKVREVLQRDEAVSGESAGIAMGLIMAGHLNQEVFNELKQYTVDTQHDKTQRGIRTGLACAAFGLQGDAEPYIKEAIGAKSNPMLRSTGICMLSMAYAGTGSPDVVRRLLEKVATDPNLDVKRYATIGIGFVLSKDPSTCLSYVAMLTEHFNGHVRYGAAMALGIACAGTGNMEAIALIEPMISDKEGFVRKGALLSLALIMCQQTDYTCPKVNGFRKQLLKKIGEKNEDSLVKFGAIIAQGLLDIGGQNAAVTMQNSDKQPDMGSMVGMMCFLHGWFWHSMHFFIALAAKPSCLVMMNENLKIPVLDYICHANSQKFAYPPRAESKKDKDVKKIETVVLSITGKKNASKKLIAEEKKRREAAASASSAAAAPSSSSTSGTAPAAEDEKMEVDQPGKSKKEKAPEKDTKPLHRLQNPARVIPAQRQLISISDARAYSPMKPLYKGGIIVADRVDKEREEKLVSEVVTQVNTPASSGNTENKPHSTFEININDF
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 1, 26S proteasome regulatory subunit rpn-2.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S1 family.
Protein: Y191_SYNY3
Sequence: MNRGAKVKTNGDNLALSTRAKKLLTKSIDTLETIIDNDQCSPQEKATIALKILEMAGIFTEFKHHSVDKLVAKAEEKIRRLQSQYPQINLSLSEPTLHQQSESIFLPGTYGEIKNFLSPEENQKIITEAIDKKEEYIKSNTTTKANQYRQSYVLFSQKIPALSALIRERIKQKLPELLGQLNFSPFEVAEIELQLTAHNDGCYYRIHNDAGSEKTASRQITYVYYFYQEPKAFSGGELRLYDTELKNNTITTHPKFQTITPINNSIIFFNSRCRHEVMSVVCPSREFAHSRFTVNGWIRKKMN
What are the official names of this protein?
Uncharacterized PKHD-type hydroxylase sll0191, ORF60-3.
Protein: OXA1_KAZSE
Sequence: MGVANTSLRYSAFNFSLGRRFKSTSETLNDLPETISEVQTQLPSIDQMTNATADIVEQASHSVGELSTHIGYLNSIGLAQTWHWPADIIQHALEYVHVYTGLPWWGTICTVTILVRLLMFPIYVKSSDTIAKNSRIKPQMDKVTKELMATTDLAEGQKIAVRRRKLLSENGIKNRWLAAPMLQLPIAIGFFNALRSMANFPVDGFANQGILWFHDLTLSDPYLGLQFITAAVLMSFSRLGGETGAQQFSGPMKRFFIILPLVSIPATMNLSTSVVLYFAINGTFSVLQTLVLRNKWFRKKLNIAEVVQHPPDPTKENSGIFAAIKENMNTARERSEKRKLMKEEEERVHELIKKKRTNERIRIIRRPELKK
What is the function of this protein?
Probably required for the insertion of integral membrane proteins into the mitochondrial inner membrane.  Essential for the activity and assembly of cytochrome c oxidase (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protein OXA1, Cytochrome oxidase biogenesis protein OXA1, Oxidase assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.