PharMolix/UniProtQA huggingface dataset:
Protein: RADA_BRUA2
Sequence: MAKTRVQFICQNCGAVHSRWAGKCDSCGEWNTLIEEGTNSGIGSGPAAMLSKRKGRAVALTSLSGEIEDAPRIVSGISELDRVTGGGFVRGSALLIGGDPGIGKSTLLTQAAAALSNRGHRIVYVSGEEAVAQIRLRAQRLGVAASAVELAAETNVEDIIATISSDNSGSKRPDLVIIDSIQTLWTDMADSAPGTVTQVRSSAQAMIRYAKQTGAAVVLVGHVTKDGQIAGPRVVEHMVDGVLYFEGEGGHHYRILRTVKNRFGPTDEIGVFEMSDGGLREVSNPSELFLGERNEKSPGAAVFAGMEGTRPVLVEIQALVAPSSLGTPRRAVVGWDGGRLAMILAVLESHCGVRFGQHDVYLNVAGGYRISEPAADIAVAAALVSSMAGIALPPDCVYFGEISLSGAVRAVSHAVQRLKEAEKLGFRQAEVPNGSGELWKDRNFRLMETAALADLVARIAASGAGKK
What is the function of this protein?
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks.  Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster.  Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB.  Does not have RecA's homology-searching function.
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: Y238_METTH
Sequence: MFGFLGRRRDEREVIEIEPDGPVDCIADFTYNFYWQHRGEKLDPDERIPGTSHTFREVVEHLKDGGEVIVRGDAGHRLASSMGADLAYFGGGGGVMDAGVVTVEGDVDTRMGISMVSGTIYVKGAVRDPIGNIIEVRSDRRGYKKFMSVTDILMNGLRAEPVNVTLEPGRMVIDDGHVRDTLGARLDADVEIIHHGNVDLSTGILMRRGTVRVMGDAGKNTGALLSGGTVIIQGDCDDFSGIDMRDGYLIVDGDAGKFLGAQRRGGVILARRGKPVPPTSESDLTEDDRRVLMEAGLRPHLFRRFS
What are the official names of this protein?
Uncharacterized protein MTH_238.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0658.
Protein: ORN_VIBCH
Sequence: MSFSDQNLIWIDLEMTGLDPEMHKIIEMATIVTDSELNILAEGPVIAIHQPESELAKMDEWCTTTHTASGLVARVRQSQVSEEEAIDQTLAFLKQWVPEGKSPICGNSIGQDRRFLYKHMPRLEAYFHYRYIDVSTIKELTRRWQPEVLKEFSKTGSHLALDDIRESIAELQFYRKAVFKI
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS51_CAEEL
Sequence: MSSVLDVTKPDFDVEAFVVKLLREKSLDGLVKEEEEMVSAVRRLDSDVHQIVYENYNKFLTATNTVRKIQDEFTQLDSEMKSLSRSMSTISTLIGNLDGVLGEKRDDILQLGSSYKVVNSLKHIFDLPHVLRSEFDERNYGEVLRMFKLAEESLSQYKDVPTVQLVLQKSKKIYDMTENQLMDQLRNPASGAELVSEAVDLLLTIGRDEDEVQKVLLTCSEQSLRVDLKELSANHSDVLDLVDKASESFIPNLTLIATTHDRLFEDKREDLITVLKTEMNSLHALVSKVFLSSSDAKDCSIVVRALDRYFRKISTCRYVIPGLDFLPLTIELINAVSKHEIDLSLTRIKEELKNGLNEVRKALINEEKDLSALASKIEQVFVHQVKTALANLLLFTASDVTFANLPPDEFRQSFSFNAHERLLVQAFHRFSELADEYESGAGEIRFVDPRVHLVFAVALQHLSNKSAVYLLNLCREQFSLSPDDGLTDITVVMSEVKTRAQKLVRCYAEKTGLSMGETLIKGCAMLVQPAATPSAVRASVRRLVEEMNTCDSELTLLLGGDSKPKDSRVSRRPITTALDAARDSLWCERIDFHLQIHFNRASIITVIVKVVLKIFIESIRLQTYSKFGVEQVQVDCYYLQRCLAALVSDEVVVNSMVDQALSSALKRCQDPVLVHPSRLAQLCEQPPANRPSSQASSLGY
What is the function of this protein?
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN) (PubMed:21613545).  The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi (PubMed:21613545).  Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the EARP-interacting protein eipr-1 (PubMed:27191843).  Important for neuronal function (PubMed:27191843).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 51 homolog, Protein fat-free homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS51 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network.
Protein: SCX2_CENHU
Sequence: KEGYIVNSYTGCKYECFKLGDNDYCLRECRQQYGKGAGGYCYAFGCWCTHLYEQAVVWPLKNKTCN
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Beta-toxin Chui2, Chui2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
Protein: NDB2_HETSP
Sequence: MNGKLLLVSLMVTMLVMQPAEAGVWDWLKKTAKNVWNSDIVKQLKGKAINAAKNYVAEKIGATPSVAGQIPFDEFMDILHYRP
What is the function of this protein?
Amphipathic peptide with potent activities against both Gram-positive and Gram-negative bacteria.  Is the most active against the two Gram-positive Bacillus megaterium and Micrococcus luteus (MIC=4. 0 uM for both).  It has relatively low hemolytic activity against human erythrocytes.
What are the official names of this protein?
Heterin-1.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: RS11_GLOC7
Sequence: MARPTKKGGAKKQKKNVPNGIAHIQSTFNNTIVTIADTRGDVISWASAGSSGFKGAKKGTPFAAQTAADNAARRAMEQGMRQIEVMVSGPGAGRETAIRALQGAGLEITLIRDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RS21_GEOSM
Sequence: MPGVKVKEAEPFELALKKFKKQCEKAGILSEVRKREHYEKPSIKKKKKAIAARKRALKKQRKMVD
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PYRH_LACLS
Sequence: MAEIKYKRVLLKLSGEALSGEKGFGFDPETAKAVAEELKEVHDLGAELAIVCGGGNVWRGVTGEKAGMERAQADYMGMLATIQNGLFIQSALENIGVDTRVMTAIEMKAVAEPYIRRRAERHLEKGRVVIFAGGTGSPYFSTDTTSALRAAEINADVILMAKNGVDGVYNADPKLVADAIKFEHLTHMDVITKGLQVMDSTASTMSMDNHIPLVVFNMNEAGNITRVVRGEEIGTTVE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U73B5_ARATH
Sequence: MNREVSERIHILFFPFMAQGHMIPILDMAKLFSRRGAKSTLLTTPINAKIFEKPIEAFKNQNPDLEIGIKIFNFPCVELGLPEGCENADFINSYQKSDSGDLFLKFLFSTKYMKQQLESFIETTKPSALVADMFFPWATESAEKLGVPRLVFHGTSFFSLCCSYNMRIHKPHKKVATSSTPFVIPGLPGDIVITEDQANVAKEETPMGKFMKEVRESETNSFGVLVNSFYELESAYADFYRSFVAKRAWHIGPLSLSNRELGEKARRGKKANIDEQECLKWLDSKTPGSVVYLSFGSGTNFTNDQLLEIAFGLEGSGQSFIWVVRKNENQGDNEEWLPEGFKERTTGKGLIIPGWAPQVLILDHKAIGGFVTHCGWNSAIEGIAAGLPMVTWPMGAEQFYNEKLLTKVLRIGVNVGATELVKKGKLISRAQVEKAVREVIGGEKAEERRLWAKKLGEMAKAAVEEGGSSYNDVNKFMEELNGRK
What is the function of this protein?
Possesses quercetin 3-O-glucosyltransferase activity in vitro.  Involved in stress or defense responses.
What are the official names of this protein?
UDP-glycosyltransferase 73B5, Flavonol 3-O-glucosyltransferase UGT73B5.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: SURE_AERPE
Sequence: MLKAIVTNDDGVHSRSLRALAESLASRGWDVVVAAPLGNWSGYSKSIGRFRGNRVYRFESRGVRFFTGDMPPAALVGTAIDIAGFEPDIVVSGINYGPNLGIYDFFSSGTIGGALEAALRGFKSVSISSACREEETDCLPEALSISLAVVETSVETLSSSAGLMVVNIPRSPRGFKVTRPCRRVPRFSGEIGEEGSLLVEKFDHSRLFSSEHDSCDGRLFSMGYIPVSLYKIDNGWIHPLDPSRDGYLKAVEDILNYKIFPSAGKQF
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNB_ECO27
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALPDGKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSTDGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRIAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETAYKVTDVIDVTIAEVRMETRSIIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YG1C_SCHPO
Sequence: MKRVNFTISGHGYILIKPNYPDHFNYRLPADMKFYKCVLTINYISVSSMSGPFTGPYEKYSSGYFSEFGPQHLFSINRYHGLRFSRQSSQEYDSVGHILYSPITYYVSGAEHVTMDSIDQRREFQDSIYTHDSSDSENIMSDSSQSECDYADLMINLDKLI
What are the official names of this protein?
Uncharacterized protein C83.12.
Protein: FET3_YEAST
Sequence: MTNALLSIAVLLFSMLSLAQAETHTFNWTTGWDYRNVDGLKSRPVITCNGQFPWPDITVNKGDRVQIYLTNGMNNTNTSMHFHGLFQNGTASMDGVPFLTQCPIAPGSTMLYNFTVDYNVGTYWYHSHTDGQYEDGMKGLFIIKDDSFPYDYDEELSLSLSEWYHDLVTDLTKSFMSVYNPTGAEPIPQNLIVNNTMNLTWEVQPDTTYLLRIVNVGGFVSQYFWIEDHEMTVVEIDGITTEKNVTDMLYITVAQRYTVLVHTKNDTDKNFAIMQKFDDTMLDVIPSDLQLNATSYMVYNKTAALPTQNYVDSIDNFLDDFYLQPYEKEAIYGEPDHVITVDVVMDNLKNGVNYAFFNNITYTAPKVPTLMTVLSSGDQANNSEIYGSNTHTFILEKDEIVEIVLNNQDTGTHPFHLHGHAFQTIQRDRTYDDALGEVPHSFDPDNHPAFPEYPMRRDTLYVRPQSNFVIRFKADNPGVWFFHCHIEWHLLQGLGLVLVEDPFGIQDAHSQQLSENHLEVCQSCSVATEGNAAANTLDLTDLTGENVQHAFIPTGFTKKGIIAMTFSCFAGILGIITIAIYGMMDMEDATEKVIRDLHVDPEVLLNEVDENEERQVNEDRHSTEKHQFLTKAKRFF
What is the function of this protein?
Iron transport multicopper ferroxidase required for Fe(2+) ion high affinity uptake.  Required to oxidize Fe(2+) to Fe(3+), which is then transported into the cell via the ferric iron permease FTR1.  Essential component of copper-dependent iron transport.
What are the official names of this protein?
Iron transport multicopper oxidase FET3.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein; Extracellular side.
Protein: DSBB_AERS4
Sequence: MIEFLRRIAAHRLAWGLLAASALFLELSALFFQYVLGLHPCVMCVYERLAILGVLSAGLLGMVAPEKWYLRWSALLLWGYSAFRGLQLALKHVDYQMNPSPFNVCSPFADFPSWAPLDQWLPWLFFPDGDCSEISWQFLSFSMPQWLVAIFAAYLLVFVVVTIGNLVKGRCCS
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYVG_VIOBI
Sequence: GTFPCGESCVFIPCLTSAIGCSCKSKVCYKN
What is the function of this protein?
Probably participates in a plant defense mechanism.  Has cytotoxic activity, active against a human lymphoma cell line with an IC(50) of 0. 96 uM.
What are the official names of this protein?
Cyclotide vibi-G.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: SYH_ACIBS
Sequence: MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQKGRYRQFHQFGVETFGVATPDIDAELIMLTARLWKRMGVDHMVQLELNTLGETDERTEYRNALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKILENAPKLHDFLKEDSLSHFQQLQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKADQSVPAVGFAMGMERLLLLLEQVEQAEIVRHCEAFLVAEPAYQSKALVLAEQLRDQLEAANSNIRIKTGSQSSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAELVPFLIEKFTK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_ECOL5
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PRL1_CRONO
Sequence: LPICPSGSVNCQVSLGELFDRAVKLSHYIHFLSSEMFNEFDERYAQGRGFITKAVNGCHNASLTTPEDKEQAQQIHHEDLLNLVLGVLRSWNDPLLHLVTEVQRIKEAPDTILWKAVEIEEQNKRLLEGMEKIIGRVQPGDTGNEVYSRWSGLPSLQLADEDSRLFAFYNLLHCGRRDSHKIDNYLKLLKCRLIHDSNC
What are the official names of this protein?
Prolactin-1, Prolactin I, PRL-I.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AQP5_RAT
Sequence: MKKEVCSLAFFKAVFAEFLATLIFVFFGLGSALKWPSALPTILQISIAFGLAIGTLAQALGPVSGGHINPAITLALLIGNQISLLRAVFYVAAQLVGAIAGAGILYWLAPLNARGNLAVNALNNNTTPGKAMVVELILTFQLALCIFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPSHWVFWVGPIVGAMLAAILYFYLLFPSSLSLHDRVAVVKGTYEPEEDWEDHREERKKTIELTAH
What is the function of this protein?
Forms a water-specific channel (PubMed:7530250).  Plays an important role in fluid secretion in salivary glands.  Required for TRPV4 activation by hypotonicity.  Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells.  Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity).
What are the official names of this protein?
Aquaporin-5, AQP-5.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Hypotonicity increases location at the cell membrane. Phosphorylation decreases location at the cell membrane.
Protein: NU1M_PHYEO
Sequence: MYLITLLSTIVPILLAVAFLTLVERKILGYMQLRKGPNVVGPYGLLQPIADAVKLFTKEPLRPLTSSVSMFIIAPILALALALTMWTPLPMPHPLINMNLGILFMLAMSSLAVYAILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSILLMSGSYSLTTLITTQEYIWLILPSWPLTMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAGGPFALFFLAEYANIIMMNALTTILFLGAYNNPMAPELYTTNFATKTLLLTMSFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWYVTMPIMLASIPPQT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NUDL_SALPC
Sequence: MDTSRLTLDHFLSRFQLLRPQMTHETLNQRQAAVLIPVVRRPQPGLLLTQRAIHLRKHAGQVAFPGGAVDSTDASLIAAALREAQEEVAIPPQAVEVIGVLPPVDSVTGFQVTPVVGIIPPNLPWRASEDEVSAVFEMPLAQALQLGRYHPLDVYRRGNSHRVWLSWYEHYFVWGMTANILRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: EFTS_EHRRW
Sequence: MKVDINAIKELRDLTGAGVGDCKDALTSCNGDIEKAKTYLREQGIAKAYKKSNKDVSDGLVAICIDGNKGAILEVNSETDFVARNEKFQKLVLNLAFLANQYGIENIEDFLKCEYANNTNINDEIMSNIAVIGENIHLNKIGCLSVSSGVVCGYIHNPIVDNLGKVGAIVALESNCDVEKLKIFARQIAMHIVATKPEALSLDVLDQNVIDKERDIIKKQVEQLNKPASVLEKIIDGRMAKFYQEVVLMNQMFIMDSQFTVSELIKKKEEELGSSINIVDYKLFIINK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y977_ACIF2
Sequence: MPSFDVVSEVDMQEVDNALHTTVKEITTRYDFKGSKASMERKEKEIILVAEDEYKLGQMIDLLSARLVKRGVDLKALEVGKVAAAAGGMERQVLSLKVGLETEVSKRMIKFLKDGKFKAQGSIQGDQLRVSGKSRDELQAAIAALRGHDFGLPVQFTNFRD
What are the official names of this protein?
UPF0234 protein AFE_0977.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RL354_ARATH
Sequence: MARIKVHELRDKSKTDLQNQLKEFKAELALLRVAKVTGGAPNKLSKIKVVRKSIAQVLTVISQKQKSALREAYKNKKLLPLDLRPKKTRAIRRRLTKHQASLKTEREKKKEMYFPVRKYAIKV
What are the official names of this protein?
60S ribosomal protein L35-4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL9_XANOP
Sequence: MDLILLQKVTNLGNLGDKVSVKPGYGRNFLVPQGKAVPATAANVEAFETKRAEYEAKASSILADAQSRATKFEGASVTICAHASTEGKLYGSVGPRDIAEAFTAAGLPLEKSEVILGEGAFRNVGEYDVVLHLHADVETTVKVIVESDA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: QUEA_BACLD
Sequence: MKVELFDFDLPERLIAQVPLKERDASRLMVLDKKTGEITHSTFKHVIDFLNAGDCIVLNDTRVLPARLYGVKEETGAKVEVLLLKQEEGDVWETLVKPAKRVKRGTVLSFGDGRLTAVCTEELEHGGRKIEFRYEGIFYEVLESLGEMPLPPYIKEQLDDRERYQTVYSKKQGSAAAPTAGLHFTEEILDALREKGVHIAFITLHVGLGTFRPVSAENVEEHDMHAEFYEMSEETAALLNRVRQEGGRIISVGTTSTRTLETIASEHDGRFREASGWTSIFIYPGYTFRAIDGMITNFHLPKSSLIMLVSALAGREHVLSAYRTAVEHEYRFFSFGDAMLIK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TODJ_PSEP1
Sequence: MSELDTARTGAVRKAADLLYEATRSGVAVVPVRNLIGETDLEAAYAVQEVNTQRALVAGRRLVGRKIGLTSVAVQKQLGVEQPDYGMLFADMARTEGEEIALDDVLQPKVEAEIAFVLGRDLDGDQLTVADLFRAIEFAVPAIEIVGSRITNWDIRITDTIADNASSGLYVLGSTPKRLCDFDSRQAGMVMERQGIPVSSGVGAACLGAPLNAVLWLARVMARAGRPLRTGDTVLSGALGPMVPVAGGDVFDVRIAGLGSVTAAFAKA
What is the function of this protein?
Converts the product of 2-hydroxy-6-oxo-2,4-heptadienoate hydrolase.
What are the official names of this protein?
TodF product hydratase.
What is the protein family that this protein belongs to?
Belongs to the hydratase/decarboxylase family.
Protein: PCNA_MACFA
Sequence: MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS
What is the function of this protein?
Auxiliary protein of DNA polymerase delta and epsilon, is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.  Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities.  Has to be loaded onto DNA in order to be able to stimulate APEX2.  Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways.  Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion (By similarity).
What are the official names of this protein?
Proliferating cell nuclear antigen, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: PQM1_CAEEL
Sequence: MSFLNNDFGSPPATSSPPTTMPKLPTIQDMLNNIGASTVNLMQPNPYLMQNQIPLPVPNLPLNPFLHLNPAISQEIIQQFIAMSFNTPNVLASIANMGDDEGPSCNPKMRRGDLLKSVSMDSTEDPPSITLDNNGDMIVPNNDKEGWCRNKKYIEQTENGYMCTVCRKVYGRYNSVSYHVTIYHRNPPIKCNVPNCQFTTREARYIHFHKNYRHGIPLPESIDQGSRKCPHCRHVSKSPAMLEKHIRRHQIKDGLSNINEAIRERTSTICDEAMEIEPAETEVDPIETKPRSCTL
What is the function of this protein?
Zinc finger transcription factor which acts as both a transcriptional activator and repressor (PubMed:23911329, PubMed:30956009).  Binds to the promoters of genes that contain the 5'-CTTATCA-3' DNA consensus sequence in their regulatory region (PubMed:23911329, PubMed:31532389).  Functions downstream of the Insulin/IGF-1-like signaling (IIS) mediated pathway (PubMed:23911329, PubMed:27401555).  Involved in normal development, lifespan, stress response, lipid metabolism, innate immunity and exit from the developmentally arrested larval state known as dauer (PubMed:23911329, PubMed:27401555, PubMed:29949773, PubMed:31532389, PubMed:33009389).  Required for stress-induced expression of hsp-90 and resistance to heat stress, perhaps as part of a systemic stress signaling pathway (PubMed:29949773).  Involved in maintenance of proteostasis (PubMed:29949773).  Under hypoxic stress increases lipid levels by positively regulating fatty acid synthesis via fat-7 expression (PubMed:33009389).  Associates with homeobox protein ceh-60 at the promoters of some stress-responsive genes to regulate expression; may require phosphorylation for transcriptional repression activity (PubMed:30956009).  Acts downstream of nhr-14 to activate transcription of intestinal metal transporter smf-3, modulating innate immunity and iron uptake (PubMed:31532389).  May act downstream of the mTORC2 signaling mediated pathway (PubMed:27401555).  May act in a mutually exclusive manner with the FOXO transcription factor daf-16 (PubMed:23911329, PubMed:27401555).
What are the official names of this protein?
Zinc finger transcription factor pqm-1, CePqM132, Paraquat responsive protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Chromosome. Nucleus. Cytoplasm. Note=Nuclear localization under normal conditions, cytoplasmic as a result of heat-stress (PubMed:23911329). Nuclear localization declines over normal lifespan (PubMed:23911329). Exposure to Gram-negative bacterium P.aeruginosa enhances nuclear localization (PubMed:31532389). Hypoxic stress enhances nuclear localization (PubMed:33009389).
Protein: RS11_GLAP5
Sequence: MAKTPVRARKRVKKQIVDGVAHIHASFNNTIVTITDRQGNALAWATAGGSGFRGSRKSTPFAAQVAAERCAEMVKEFGLKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.