PharMolix/UniProtQA huggingface dataset:
Protein: MAP22_LEPMJ
Sequence: MAAQVEDDVANLKLDDSTTKPTNGTSQPDSKLSAEAEDSDDDAEGDGNGTGEAGADGAAKKKKKRKPRKKKKAGTSATAGAKSQTSPPRVLISDLFPNDSYPEGEICEYRDENSYRTTNEEKRHLDRMNNDFLTDYRKGAEIHRQVRQWAANWIKPGMTLTEIAEGIEDSVRALTGHQGLEEGDAQKAGMGFPTGLSINHCAAHYTPNAGNKVVVNYEDVMKVDFGVHINGRIVDSAFTKTFDPVYDPLVEACKAATNAGIKEAGIDVRMSDIGAAIQEVMESYEVEIGGKMLPVKCIRNLNGHSIGHYTIHGGKTVPIVKGSDQTKMEEGETFAIETFGSTGKGYVRDDMETSHYALRPDAPKVALRISSAKSLLASITKNFGTLPFCRRYLDRLGHDKYLLGLNNLVSSGIVEAYPPLCDIKGSWTAQSEHTFVLRPTCKEVLSRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2-2, MAP 2-2, MetAP 2-2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_KOSOT
Sequence: MKIHELPQEVILKIAAGEVVTGCFSVVKELVENALDAEATTVEVEIKAGGKEYIRVSDNGIGMLPEELKMAIKPHTTSKIQCIEDLERILTYGFRGEALSTISSVSRMRISSMPDNADLGLTIEISGGKIVREKSYIGPKGTTVEVYDLLFNTPARRKFLKSQRVEGRMVTEIVQRFILAIPDAGFKYIRDGELIYDLTPAERILERIPVVFPELSTTDLLEVKEETSGISITGYITFPERTRFNRLGEMVFVNGRYVRQPELNYAIEKGYGESLEKGRFPFAILFISVNPEMIDVNIHPQKLEVRFSNPSLVFDAIKRAVRNTLRTSGTSILRIEKRPFPGSSTNYSGIQQDTKKQESDNPEKARGYGTHLRETHWEQRDHFEKRKVPLHYQPDNELLLNIERTASRRFEKTEAKETGEPRLFGVFGERYILAETKDGLLIVDQHAAHERLIYEKLKKAAKIQSQKLLSPIRLTLEDSRKSLLREKKNDVEKLGFQISFEGDRIFLTGIPSILSESVAVNALNEVLDELRLEGLEEPEKIFDHLLSTLACKSAIKTGDRLSESEAKELLEKLLEEEILFCPHGRPVSMLIRFKDLDRHFSR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: NADK_RICCK
Sequence: MNINKIALIYNKDYKSLAIIEEIKKLYNYCEVEEAEVIIVIGGDGALLHNIHCYMHLNIPFYGVNLGSLGFLMNTLDTKNLLQNIHDSTVTILNPLLMQAKDTSGQIYTALAINEVSIFRKTNQAAKFRIDVNGIERMSELVADGALVATPAGSSAYNLSAGGPILPLESNMLCLTPICAFRPRRWHGALLLSSATIKFEIFNTTKRPVNATADFQEFNNIIQVTVSSTKDKPIKLLFNKNHTLEDRIIKEQFGG
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_CHLCH
Sequence: MCNILIPSNMKTGIKKVKLHVKKNDTVTVISGNDKGKMGKVLKVFPVASRVIVEGVNIRKRHMRPLQGQTQGRIIEREFPIHSSNVKKS
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: NAGB_CITK8
Sequence: MRLIPLTSAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPLTAYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYHSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRNYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDGDVNQVPKYALTVGVGTLLDAEEVMILVLGHQKAQALQAAVEGNVNHMWTISCLQLHPKAVVVCDEPSTMELKVKTLKYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: URED2_BRASB
Sequence: MSASAPEPPRLDLSFVRRGGRTVIDRRLFAWPFVLTRSFHTDGARPDLLSVILQTGSGAVHGEDRLTQRFTLREGAAVSVTTQGATSVHRAEPGARAVEQVQLRVAAGASLDYRPEPRILFPDAALCQVLELDCAADAVALVTDAFTMHDPDGQGRLFRELDSTVIVRRPSQEPLLIDRMQLCDPGTALFKGRRAFGSAVLMLPDMHDRAAIRLRVIDTLAHIDDLYAAASLLPQSVGIGIRLAARELRQLRAGFDAVAALVREIDLGARAAQAPSAAATARPTAA
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 2.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_COREF
Sequence: MTSPVDASSSKEKLTLAEKVWRDHVVSKGENGEPDLLYIDLQLLHEVTSPQAFDGLRMAGRKLRRPDLHLATEDHNVPTEGIKTGSLLEINDQISRLQVSTLRDNCKEFGVRLHPMGDVRQGIVHTVGPQLGATQPGMTIVCGDSHTSTHGAFGAMAFGIGTSEVEHVMATQTLPLKPFKTMAIEVTGELQPGVSSKDLILAIIAKIGTGGGQGYVLEYRGEAIRKLSMDARMTICNMSIEAGARAGMIAPDETTFEYVKGREMAPTGADWDEAVAYWKTLPTDEGAEFDKVVEIDGSSLTPFVTWGTNPGQGLPLSESVPDPEDFTNDNDKAAAEKALQYMDLTPGTPLREIKIDTVFLGSCTNARIEDLEIAAEILKGRKIADDIRMMVVPSSTWVKQEAEKLGLDKIFIEAGAEWRTAGCSMCLGMNPDQLKPGERSASTSNRNFEGRQGPGGRTHLVSPAVAAATAVRGKLSSPADL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RL16_CAMJE
Sequence: MLMPKRTKYRKMMKGRNRGYANRGTEFTFGEFALKATEAGRINSRQIEAARIALTRFVKRQGKTWIRVFPDKPLTKKPLETRMGKGKGAVEEWVMNIKPGRIIYEMAGVSEEMAREALTLAMHKLPFKTKFVTRESQNEIY
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PDUX_CITFR
Sequence: MAVAQCPASCGELIQGWILGSEKLVSCPVEWYSTVEVTSGSPLTDERPLSRAMVDRLLQHWQYPAHLSQDIRIDVQSTIPIAKGMASSTADIAATAIAAAHYLGHQLDEPTLAQLCVSLEPTDSTVFRKLTLFDHNNASTQIGCEAQPQLDLLVLESPETLRTADYHRIPRHSGLQAGAAALQRAWEKVQEACISQNPYRLGEAATLSAIASQLLLPKPDFDSLLALVEECDLYGVNVAHSGSVVGLMLDRNRHDVDYIKWMLTQKKLTIHWPEQHLLRMVTGGVELQ
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low (Probable).  This gene probably benefits from its induction via the Pdu promoter, rather than a physical interaction with the BMC (By similarity).
What are the official names of this protein?
L-threonine kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. PduX subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALN1_DICDI
Sequence: MNSENIIKVIKGKKVVINGEIKPASILIKNGIIIDIKDYSSEIKEEHEVLIEEEKLVIMGGLVDSHVHINEPGRTEWEGFLSATSAAASGGVTTIIDMPLNSSPVTTTFENLQTKIESMPGKLRVDVGLLGGIIPGNSSEISRMVLEGGVVGFKSFLVHSGIDEFPHVKEDDIQEAMNVMKKLKDEQGGRDVVMMFHAEIEEPIKEATERLQRENADPKLYDTFLKSRPRVSENIAIDKVIELTKKNMIKTHIVHLSSSDAIEAIHEAVHNDGVPITAETTYHYLYFESEQVPYGNTLYKCCPPVRESENKDLLWKAVTNGTINIIVSDHSPCTLDLKLIEQGDFMKAWGGISSLQLGLPIIWTEASKRGVPLAKLSEYMSDAPSRLVGLNDRKGSIKIGRDADFVIWDPEESFTVDQGLLMVKNKNSPYHGEKLLGVVHHTILRGNKIFSKGDQTISKIIGKRLIQTKIHTNPIYPSPTLPTIELLNSLTEQKTFFDCIHLLFEAAPPLANALFSKRPFSSYQQLIDQAYSIIQSLNESDKIQVINAHPRIGVSASQVKNSSSISYREQSCDKDSSIDQSILENLTQLNQQYESKFGFKFVVFVNGRPKNEIIPILQNRLNNNDKQKELNLGLSEMIEISKSRLLKLL
What are the official names of this protein?
Probable allantoinase 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
Protein: YQ29_SCHPO
Sequence: MNLICSILPKKEPSYLKLWRKQVIYQVLTDRFALDEDNFYAKASGNLYLGGTWKGITRNLDYIKSLGCTAIWISPIVKNISETTDCGQAYHGYWAQDMTQLNENFGTEEDLKELVNAIHEKNMLCMVDIVVNHMGHAGSKPVNFLLYQPFNSGKYYHNWQFVQNYDDPHETITGWLGDSHVNLPDIRTEKNEVRKFFQNWVSDLIKRYQFDGIRLDTAKHVEKSFFPTFIEAANVFTTGEVFHGDPKVVGDYQKYLPSTLNFPLFFQLRETFLDPKHSMFSFYDKAVLDVRHYFKDVTVLCNFLENHDFPRFFHETKDIALALNALTALIFMDGIPIIYYGQEQMFDGGSDPDNREGLWKSKYNTSNPMFRHLSSMIRTRQNLVETYPEFTYVLSFQLYIDDSVYVFTRPGVIIAISNEGSTSSFKVEIDLKEHWKEVPSSFTDILTQKTIPCKDHKLKIKSKSGLPKILISSDPSFL
What are the official names of this protein?
Uncharacterized glycosyl hydrolase C11E10.09c.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: TRPA_STAAM
Sequence: MTKLFIPYIMGNKDLIENATLLSENGADIIEIGVPFSDPVADGPVIMEAGQQAIKQGITIDYIFNQLEKHGDQIKCNYVLMTYYNIICHYGEQAFFEKCRDTGVYGLIIPDLPYELSQRLKQQFSHYGVKIISLVAMTTDDKRIKDIVSHAEGFIYTVTMNATTGQNGAFHPELKRKIESIKAIANVPVVAGFGIRTPQHVADIKEVADGIVIGSEIVKRFKSNTREEIIRYLQSIQQTLNN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TRMB_SHIFL
Sequence: MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPVMGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDLMFERVK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: DISA_CLOAB
Sequence: MNDLRLKKDRKLLEILKTMAPGTDMREGLENILRAKTGGLVVLGDNEEVMKLSDGGFKINSEYSASYIYELAKMDGAIILSSDLKKIVRANVQLVPDSSIPTFETGTRHRTAHRVAKQTGNVVVAISQRRNVITIYKDDIKYILRDSSIILARANQAIQTLEKYVAVLDRVMGNLNLLEFEDLCTLHDVVAAIQRTEMVMRVVTEIDRYICELGNEGRLISMQLNELVKNVEQDGMLIIRDYCQNEMNYSKVCETIQSMSSEEFLNSEAISKVMGYGDVPLIDTLISPRGYRMTSKIPRIPFIVIENLVKNFKELKKILEASHEDLDKVEGIGEARARAIKSGLRKLKEQTIIRKQL
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation.  The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: RSC30_YEAST
Sequence: MMDMQVRKVRKPPACTQCRKRKIGCDRAKPICGNCVKYNKPDCFYPDGPGKMVAVPSASGMSTHGNGQGSNHFSQGNGVNQKNVMIQTQYPIMQTSIEAFNFSFNPSVDTAMQWTKAASYQNNNTNNNTAPRQNSSTVSSNVHGNTIVRSDSPDVPSMDQIREYNTRLQLVNAQSFDYTDNPYSFNVGINQDSAVFDLMTSPFTQEEVLIKEIDFLKNKLLDLQSLQLKSLKEKSNLNADNTTANKINKTGENSKKGKVDGKRAGFDHQTSRTSQSSQKYFTALTITDVQSLVQVKPLKDTPNYLFTKNFIIFRDHYLFKFYNILHDICHINQFKVSPPNNKNHQQYMEVCKVNFPPKAIIIETLNSESLNNLNIEEFLPIFDKTLLLEFVHNSFPNGDTCPSFSTVDLPLSQLTKLGELTVLLLLLNDSMTLFNKQAINNHVSALMNNLRLIRSQITLINLEYYDQETIKFIAITKFYESLYMHDDHKSSLDEDLSCLLSFQIKDFKLFHFLKKMYYSRHSLLGQSSFMVPAAENLSPIPASIDTNDIPLIANDLKLLETQAKLINILQGVPFYLPVNLTKIESLLETLTMGVSNTVDLYFHDNEVRKEWKDTLNFINTIVYTNFFLFVQNESSLSMAVQHSSNNNKTSNSERCAKDLMKIISNMHIFYSITFNFIFPIKSIKSFSSGNNRFHSNGKEFLFANHFIEILQNFIAITFAIFQRCEVILYDEFYKNLSNEEINVQLLLIHDKILEILKKIEIIVSFLRDEMNSNGSFKSIKGFNKVLNLIKYMLRFSKKKQNFARNSDNNNVTDYSQSAKNKNVLLKFPVSELNRIYLKFKEISDFLMEREVVQRSIIIDKDLESDNLGITTANFNDFYDAFYN
What is the function of this protein?
Component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning.  RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA.  The reaction requires ATP and involves an activated RSC-nucleosome intermediate.  Remodeling reaction also involves DNA translocation, DNA twist and conformational change.  As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton.  This subunit is required for transcription of ribosomal protein genes and genes involved in the integrity of the cell wall.  Together with HTL1, LDB7, NPL6, RSC3 components, defines a fungal-specific module within the RSC complex that plays a role in many cellular functions including the maintenance of cell wall integrity.
What are the official names of this protein?
Chromatin structure-remodeling complex protein RSC30, Remodel the structure of chromatin complex subunit 30.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to centromeric and flanking chromatin. Association with these loci is dependent on STH1.
Protein: PDK4_RHIFE
Sequence: MKAARFVMRSARSLSSAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSSAFLRQELPVRLANILKEIDILPDRLVNTSSVQLVKSWYIQSLMELVEFHERSPDDQKVLSDFVDTLITVRNRHHNVVPTMAQGIIEYKDSCTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPNCNVAAVVQDAFECSRMLCDQYYLTSPELKLTQVNGKFPGEPIHIVYVPSHLHHMLFELFKNAMRATVEHQENEPSLTPVEVTVVLGKEDLTIKISDRGGGVPLRITDRLFSYMYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLHLYSLSGYGTDAIIYLKALSSESVEKLPVFNKSAFKHYQMSIEADDWCIPSKEPKNLAKEKVAV
What is the function of this protein?
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2.  This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate.  Inhibition of pyruvate dehydrogenase decreases glucose utilization and increases fat metabolism in response to prolonged fasting and starvation.  Plays an important role in maintaining normal blood glucose levels under starvation, and is involved in the insulin signaling cascade.  Via its regulation of pyruvate dehydrogenase activity, plays an important role in maintaining normal blood pH and in preventing the accumulation of ketone bodies under starvation.  In the fed state, mediates cellular responses to glucose levels and to a high-fat diet.  Regulates both fatty acid oxidation and de novo fatty acid biosynthesis.  Plays a role in the generation of reactive oxygen species.  Protects detached epithelial cells against anoikis.  Plays a role in cell proliferation via its role in regulating carbohydrate and fatty acid metabolism (By similarity).
What are the official names of this protein?
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4.
What is the protein family that this protein belongs to?
Belongs to the PDK/BCKDK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL3_CLOB6
Sequence: MKKAILGKKLGMTQIFNENGKVIPVTVIEAGPCTVIQKKTVEKDGYEAIQVAFGDIREKLRNKPVKGHFAKAGVSVKRHIKEFKLEDSNSLEIGQEIKADVFEAGERVDISGVSKGKGFQGTIRRWNAHRGPMTHGSKFHRAVGSMGASSDPSRTFKNKRMPGHMGNVNTTVLNLEVVRIIPEKNLILIKGGVPGPNKGLVQIRNTVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ARLY_BACHK
Sequence: MSKLWGGRFTEEAEAWVEEFGASISFDQQLVNQDINGSIAHVTMLAKQGIVTKEEAEKIKIGLQYLLEEAKQNKLHFSVEAEDIHLNIEKMLIEKIGEVGGKLHTGRSRNDQVATDMHLYLKEKVEHIMKATKQLQTVLVHQAENNIETIMPGYTHLQRAQPISFAHHILAYFWMLERDVNRYEDSLKRINISPLGAGALAGTTFPIDREYSAELLGFNGIYENSLDAVSDRDFILEFLSNSSMLMMHLSRFCEELILWSSQEFQFIEMSDQYATGSSIMPQKKNPDMAELIRGKTGRVYGNLFSLLTVMKGLPLAYNKDLQEDKEGMFDTVKTVEGCLHIMAGMLETMTVNKEKMGQAVTQDFSNATEIADYLANKGLPFRQAHEIVGKLVLHCTQKGIYLIDVPLATYKEMSALFEGDLYEVLSPYAAVKRRNSAGGTGFEQIEKALEKAKGLVGEIVGIK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_LEGPC
Sequence: MANIKSAIKRARQNVKLRQHNASARSMYRTYIKNVLKAVESGDQEAARAAYTKAQPVIDKAANKGLIHKNKAARIKGRLVARLKAMAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RBFA_LACE2
Sequence: MRKNSVKNTRINGEVLKELSNIIRSEIKDPRINPMTSVVAVEVAPDLKTCKAYISVLGDEKSQKDTITGLKSAEGYIRRQLARTVNLRNTPEIRFILDQSIEYGINMSKLIDEVTEHDNKMHVEVEDETE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_ECO81
Sequence: MNAEKSPVNHNVDHKEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNPITNSFKLGPGVDVNYMLHTQNK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-octaprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone-8 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: TYW4_GIBZE
Sequence: MTKEKPSSTRVAKTQALDDLIMGTNSSSIVSKRSVERLYYPNELHFFRYFVNKFQRRAPLINRGYWLRLRAIDSRVEERWSLISGQEDVDYPDLMRKKRAIVLGTPQLSELLGEDPYVSEKETDHLLLRSDKYCQVGCDLRELETLRKCLESFLPLFECSVLFVAEVSVTYMDTISADALIQWASYIGQAEFCLLEQILPHGPDHPFASTMLKHFNKLNTSLKSVHQYPTVNSQRSRFEKRGWNSVDVWDLWEAWNSEVFLNSSERAALDDVEPFDEWEEFILFARHYIVLHATSYHRGGKGAGQQMLASPPGKHVKANMVATKSLGAPKRRFGSPLVASSPEGGQYLVHTLGMGINARLDSCDIYSIQESSTSLEMAPVGPSARICHTTTDLGQGDLLLVGGRASPSKAFSDCWVLKKSSNSWEKTFDLPVPLFRHSTVNLPGSSLALVLGGKTGPSEISSDYFIFHPVRGWLKCAVSGVSPNSTFGAFAIASTSLGSKNGHFEGLLAGGIDGEGKINNQAYFWTVDVTTHEPIIHFESVQNYDQHSWALSVFGAQTANIESLSFVCGGVGQDPSSQGQSMACLTVKGKSLAVHLVDLGEKAGQLPFMVGSATVSSGSQLVIVGGGATCFSMGTFWDTGVYKIDLEGVVSEMIPGRTIHNKPVVVGYQNSPKLTQPTTDGVYPGPQSNAFITAIPKIKLQSKSDFEKLVQNRKPVIIEGLDLGGCVEKWNSEYVIQSVGETKEVVVHECQTSTGKMDFNSKNFRYVTESFSSFMTKAARGEALYLRALSEEKPTEAPANLAEDFPGLADDFRLPEELGSVKDRMFSSVLRISGRANMWLHYDVMANVYTQIQGSKRMVLFPPTDVSHLAFAPGASSSSLDIFSALDTHQLASTNPHEAFLNPGDLLFIPAMWFHTASPVTDLSVAVNVFFRDLESGYSTGRDVYGNRDLAAYEKGRQDISRITKSFDRLPSEIRQFYLRRLADELLHE
What is the function of this protein?
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.  May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues (By similarity).
What are the official names of this protein?
tRNA wybutosine-synthesizing protein 4, tRNA-yW synthesizing protein 4, Leucine carboxyl methyltransferase 2, tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase, tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LCMT family.
Protein: PHK_NITEU
Sequence: MTQLPQPLTPDELQKIDAYWRAANYLSVGQIYLLDNPLLQTPLTLQHIKPRLLGHWGTTPGLNFIYAHLNRIIRRDDLNMIYIAGPGHGGPALVANTYLEGTYSEHYPDISQDIQGMKHLFRQFSFPGGIGSHATPEIPGSIHEGGELGYALSHAFGAVFDNPDLIAACVVGDGEAETGPLATAWHSNKFLNPVHDGAVLPILHLNGYKIANPTILARISREELDQLFQGYGYQPYIVEGEDPLTMHQLMAGTLDQVLAEIRSIQTRARLDGVTQYPRWPMIILRTPKGWTGPATVDGLKTEGSWRSHQVPLSELAKKPEHIQQLEAWLRSYRPEELFDTQGRLVEPLQTLAPLGNRRMGANPHANGGSLMKQLRMPDFRKYAVEIVQPGQIEAESTRIMGSFLRDIMCLNLKTCNFRVFGPDETASNRLGSLYDVTPKTWLAETLPEDEHLAPDGRVMEILSEHTCQGWLEGYLLTGRHGLFSCYEAFIHIVDSMFNQHAKWLKVSKEIPWRRPIASLNYLLTSHVWRQDHNGFSHQDPGFIDHVINKKADTIRIYLPPDANCLLYITDKCLRSRNFVNVIVAGKQPQLQWLDMDAAIKHCTAGIGIWGWASNDQAGEPDVVIACAGDVPTIEVLAAVSILREHLPDLRIRVINVVDLMTLQHDREHPQGLSDREFDTLFTTDKPIIFAYHGYPWLIHRLTYRRTNHANLHVRGYKEEGTTTTPFDMTVLNDMDRFHLVDDVIDRVPHLGYKAAYLRQIMRDKLVEHREYINRHGEDMPEIRDWKWTAP
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: MSA_STAAM
Sequence: MKYLILSLVANLLVFGVLSAIGLNINILAAMMIVLVIPIMISGILFFKTNIDKTYIFFNIIFIDFYYYIYNVHLMTLPKFNNYIKAEMMELEDIDVLITSKDFGFDEILFYTLYLLLILIVLYYLKKQVKHKI
What is the function of this protein?
Accessory element involved in the expression of sarA and several virulence factors.  Modulates SarA production and/or function in a strain-dependent manner.  Affects the transcription of the accessory gene regulator (agr) and genes encoding virulence factors including alpha toxin (hla) and protein A (spa) (By similarity).
What are the official names of this protein?
Protein msa, Modulator of SarA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TOLB_ECOLC
Sequence: MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQWAGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVGQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQNQDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRPC_AGRFC
Sequence: MSDILKKIETYKLEEIAAAKAKVSLADLKAMAADQSAPRGFYKALRAKQAAGKFGLIAEIKKASPSKGLIRPDFDPPALAAAYEAGGAACLSVLTDTPSFQGAPEFLTAARNACALPALRKDFMFDTYQVHEARAWGADCILLIMASLSDDEAKRLEDEAFALGMDVLIEVHDAEETERALKLTSPLLGINNRNLRTFEVGLETSEKLAGLVPADKLLVGESGIFTFEDCQRLEKSGISTFLVGESLMRKDDVTAATKALLTGHSGILAAE
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.