PharMolix/UniProtQA huggingface dataset:
Protein: MFSD8_HUMAN
Sequence: MAGLRNESEQEPLLGDTPGSREWDILETEEHYKSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKIDPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPRKEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSAFLGILNIILILAILREHRVDDSGRQCKSINFEEASTDEAQVPQGNIDQVAVVAINVLFFVTLFIFALFETIITPLTMDMYAWTQEQAVLYNGIILAALGVEAVVIFLGVKLLSKKIGERAILLGGLIVVWVGFFILLPWGNQFPKIQWEDLHNNSIPNTTFGEIIIGLWKSPMEDDNERPTGCSIEQAWCLYTPVIHLAQFLTSAVLIGLGYPVCNLMSYTLYSKILGPKPQGVYMGWLTASGSGARILGPMFISQVYAHWGPRWAFSLVCGIIVLTITLLGVVYKRLIALSVRYGRIQE
What is the function of this protein?
May be a carrier that transport small solutes by using chemiosmotic ion gradients.
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 8, Ceroid-lipofuscinosis neuronal protein 7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
Protein: ALKMO_HUMAN
Sequence: MKNPEAQQDVSVSQGFRMLFYTMKPSETSFQTLEEVPDYVKKATPFFISLMLLELVVSWILKGKPPGRLDDALTSISAGVLSRLPSLFFRSIELTSYIYIWENYRLFNLPWDSPWTWYSAFLGVDFGYYWFHRMAHEVNIMWAGHQTHHSSEDYNLSTALRQSVLQIYTSWIFYSPLALFIPPSVYAVHLQFNLLYQFWIHTEVINNLGPLELILNTPSHHRVHHGRNRYCIDKNYAGVLIIWDKIFGTFEAENEKVVYGLTHPINTFEPIKVQFHHLFSIWTTFWATPGFFNKFSVIFKGPGWGPGKPRLGLSEEIPEVTGKEVPFSSSSSQLLKIYTVVQFALMLAFYEETFADTAALSQVTLLLRVCFIILTLTSIGFLLDQRPKAAIMETLRCLMFLMLYRFGHLKPLVPSLSSAFEIVFSICIAFWGVRSMKQLTSHPWK
What is the function of this protein?
Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids.  Ether lipids are essential components of brain membranes.
What are the official names of this protein?
Alkylglycerol monooxygenase, Transmembrane protein 195.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family. TMEM195 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MVD1_RAT
Sequence: MASEKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTAAISKDFTEDRIWLNGREEDVGQPRLQACLREIRRLARKRRSTGDGDALPLSLGYKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVEGDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRVLILVVSAEKKPTGSTVGMQTSVATSTLLKFRAESIVPERMKEMTRCIQEQDFQAFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNAHHGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFPPAANGDKFLKGLQVAPVLLSDELKTSLATEPSPGGVQYIIATQVGPGPQVLDDPHHHLLGPDGLPQRDL
What is the function of this protein?
Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP).  Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
What are the official names of this protein?
Diphosphomevalonate decarboxylase, Mevalonate (diphospho)decarboxylase, MDDase, Mevalonate pyrophosphate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the diphosphomevalonate decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTGE_EMENI
Sequence: MRGAILATAAAFAGTAVADMHMRRHAHEGLHHRALHASSAVPEEECGCTTEVITYWGEPTTIPLSVPTSTVTSETTETVHSTSYSTVTVTATSSAAPVETPSETPSPTPEVTLPTAGVTSYSETGTYTIPATTITVTDTTTVCGATTTELPSGTHTYGGVTTIVETATTITCPYATVKPTGSTVTSVIETTTYVCPSAGTYTIAPTTTFVPTSTVVVYPTPETVTPGTYTNPGTTITVTRTEDVYVCPYTNGNVPTSVPALPTTSAASTTTAVPSSSTTTSSATSVPTGASGNKMGMTFTPYNNDGSCMAKNDVLEQVGLIKGKGFSHVRVYGTDCHTLEYVGAACSTHGLKMILGVNVEGSTGFDGARSQFKDITNWGQWDLVSLIVVGNEVVTSNIASAAQLASFVSEGASAFSAAGYTGQVTTAEPIDVWLSNGATLCPVVDILGANLHPFFNPEFTAAEAGTLVSNQIKDLKQVCTGKDVINLETGWPNAGSANGKAIPGQSQQTTAIKSLVEKVGDVSVFFSYADDGWKSKFATSDKYNVEQHWGCIDQF
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase btgE, Beta-D-glucoside glucohydrolase btgE, Cellobiase btgE, Gentiobiase btgE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
Protein: RL15E_SULIY
Sequence: MTLSVYHYIENTWNSEEWKKGVLRQRFIEWRKEPSIVRLAKPTRLNRARSLGYKAKQGFVIVRVRVRRGGLNKPRPNKGRRPKRMGVYGYGPAKGYKWIAEERAARKYPNLEVLGSYYVGEDGLYKYYEIIMVDPSHPVIKNDPNYKWLQDPSNRNRVFRGLTSAGKKARGLRKSKGFKGTVKHKWSRKQKEREEKKRHEASKYYRLQRYDKIPGK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: RRT14_PICST
Sequence: MSFKSTASKHQAQTTVSKLFANILPNHTIGNDEDKQEKLSSTQLLSNQLKQSSVPLKKVKKKTNAKIKKINDSNTKFKKFVKYNIIKSREEHTVEEQKYLKKLVKRNASQIKNLSHIDNMQIEEELSDVRASLIDKIGKKENKRLRKRKLTSAKNSKFDDFDNKVKRGFISVPGLTPGLAPIDYNESDSE
What is the function of this protein?
Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription 14.
What is the protein family that this protein belongs to?
Belongs to the RRT14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ASNA_LIMF3
Sequence: MSLIVPENYDPKLSIRETEEAIRYIRETFQDEIGKELNLQRMSAPMFVEQSTGLNDNLNGVEAPVSFTMKDLPGETIEIVHSLAKWKRFALKKYGFGLHEGLYTNMNAIRKDEDLDNFHSIYVDQWDWEKVIAKEERTEATLKATVRQVFKVIKHMEHEVWYKFPQAVYHLPDEIHFVTTQGLEDRWPELSPMEREDKIAKELGCVFVMKIGDKLQRSGEPHDGRAPDYDDWSLNGDIIFWYEPLQTKLEVSSMGIRVDERAMKEQLEKAHATDRAELPFHRDLLAGKMPYTIGGGIGQSRLCMLLLGKAHVGEVQASIWPEEMKEACAKAKIQLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_BORA1
Sequence: MSQRYLRMDLSIALGALPQWQAHPTRQALQKRYRFDHFNAAFGFMSRVAMFAEKIDHHPEWSNVYNRVDVVLTTHDAGGVTELDVRMAQFMDEAAAQAGATGLSLPVY
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: KTHY_LEGPC
Sequence: MSSLTGKLIVIEGLEGAGKSTAVNLVVELLSQKKISTITTREPGGTRIGEILRSIIKNPEYNNVLDDRSELLLLYAARIQLIEQVIKPALNEGQWVIADRFELSTLAYQGGGRKMDMRVINELSNFCLKGFKPDLTLYLDINPELGMIRAKSRGKFDRIEQESIEFFHRIHDTYHILVKQNPEIMMIDANRPLEDVQSSIQSVIEEFIEHNL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: LEPA_LEGPC
Sequence: MLFARRLEQLKDLNRIRNFSIIAHIDHGKSTLADRFIQICGGLTEREMSSQVLDSMDIERERGITIKAQCVSLNYTAKDGKTYLLNFIDTPGHVDFSYEVSRSLAACEGAILVVDAAQGVEAQTLAVCYTAIDQSLTVLPVLNKIDLPQAEPERVISEIEDIIGLDAQDAIRVSAKSGLGVNDVLEALVANIPPPKGDVHAPLQALIIDSWFDSYLGVVSLVRIVNGAIRKGDKMRVMSTGRAYEVDQVGIFTPKRTKLDALYAGEVGYVVAGIKEIQGAPVGDTLTLDRNPADKVLPGFQRVKPQVYAGLFPVSSDDFEAFREALAKLSLNDASLFYEPESSEALGFGFRCGFLGMLHMEIIQERLEREYNLDLISTAPTVVYQIVTQKGETLLIDNPSHLPPTPQIKEMYEPIVRANILVPQDYLGPIITLCVERRGVQVSMTYSGRHVSVVYDIPMSEVVSDFFDRLKSVSRGYASLDYNFQRFQIADLVKMDILINSERVDALAVIVHRDSAHSRGKLIAEKMQQLIPRQMFDVAIQAAIGSHIIARQTVKALRKNVTAKCYGGDVTRKRKLLEKQKAGKKRMKQVGHVEIPQEAFMAVFQTDKKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RAB15_MOUSE
Sequence: MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIDVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQKRQVGREQGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELDGLRTRASNELALAELEEDEGKPEGPANSSKTCWC
What is the function of this protein?
May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal.  EHBP1L1.
What are the official names of this protein?
Ras-related protein Rab-15.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: PIC1_RHIRD
Sequence: MGLPFQIEYGQTTGRPELIEDALRQFSAALALTADAGGLYVHGYDESRNQRWANPASGKSPAIWARAVGWLAMALVDALVILPDDSATAELRERTRRLLAGIIARQTQAGLWMQVLDNQGLAGNYAETSASAMFAYALLRAARLGLLRGEEAKAALSAGRQALAALLETRLELDEQGVARLTGIVHVAGLGGFDGNYRDGTPDYYLTEPVVSDDAKGVGPLMMAYAESLLLAR
What is the function of this protein?
Seems to regulate the surface properties of the bacterium in the presence of plant cells or plant cell extracts.  Mutations in this protein are responsible for an increased aggregation of the bacteria in the presence of pea root cap cells.
What are the official names of this protein?
24.9 kDa protein in picA locus, ORF1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 88 family.
Protein: ATPG_STAS1
Sequence: MGSLKEIDTRIKSTKKMKQITKAMNMVSSSKLRRAESNAKQFRPYMEKMQDAITAVAGSDKNSRHPMLQQREVKKSAYLVITSDKGLAGAYNANVLKHLIKDIEEKHASKDDYSIVVLGQTGVDFLKNKGYDIHDSLIDVPDQPSFKEVQAIAKKAIGLYSEGEVDEVKIYFSHFVSVLENTPSTKTVLPLSPEDSSLGHGQMSSYEFEPDKEAILSVILPQYVESLIYGTILDAKASEHATRMTAMKNASDNASEIIDDLSIQYNRARQAAITQQITEIVGGSVALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1341_STAAM
Sequence: MSNSDLNIERINELAKKKKEVGLTQEEAKEQTALRKAYLESFRKGFKQQIENTKVIDPEGNDVTPEKIKEIQQKRDNKN
What are the official names of this protein?
UPF0291 protein SAV1341.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_UREP2
Sequence: MAKKNIKQKKDNRIAIDVKKHIKKVDVGVFDGTFVFTSPLSISELAPKLNKSPNEIIMRYFKKGVVYNLNTILDEEQIGELCLEYDLDFKIEKNVNTENLLENIYFDDLEIDLVARAPIVTIMGHVDHGKTTLLDTIRKSSITASEAGGITQHIGAYQIIKDNRAITFIDTPGHEAFTEMRARGANLTDIVILVVAADDGIKMQTEEAIDHAKAANVPIIVFVNKMDKYEANPEKVLNQLSAKEIVAEELGGDVVFVKGSALKNEGISELLDSILLIAELNNYKANPNRLAYGTTIEANLDKGHGPLATLLVQNGTLRKGDYLVVGSTYGKIRNMFDEYDNEIEIALPSKPVKVSGFEEVPTAGDKFLALADEKQARAIANDVKQKKMRLERAMLQSSDIRTKIANGELKNINLIIKADVQGSLEALKGIFSSINIEGVTTTLIRSAIGTISESDVRLAQTSDAIIIGFNVRASRIIKDLADSVGVQIMNYDIIYKFKEDLELWMKGTLDPIIIEEVIGEAKVLKLFKHSQVGTICGCRVINGKIKRNALVRVLRDGIVIYNSKIATLQHNKDSVNEVIADKECGLTIANFNDIKENDIIEVYIKVEKKHDEVK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURP_METMP
Sequence: MIPKEEIMGIFEKYNKDEVTIVTVGSHTSLHILKGAKLEGFSTAVITTKDRAIPYKRFGVADKFIYVDQFSDISKEEIQQQLRDMNAIIVPHGSFIAYCGLDNVEDTFKVPMFGNRAILRWEAERDLEGQLLGGSGLRIPKKYGGPDEIDGPVMVKFPGARGGRGYFPCSSVEEFWRKIDEFKAKGVLTEDDVSKAHIEEYVVGANYCIHYFYSPLKDQVELMGIDRRYESSIDGLVRVPAKDQLELDIDPSYVITGNFPVVIRESLLPQVFDMGDKLVAKAKEEVNPGMLGPFCLQSLCNENLELVVFEMSARVDGGTNTFMNGSPYSCLYTGEPLSMGQRIAKEIKLALELDMIDKVIS
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SODC_BRUAB
Sequence: MKSLFIASTMVLMAFPAFAESTTVKMYEALPTGPGKEVGTVVISEAPGGLHFKVNMEKLTPGYHGFHVHENPSCAPGEKDGKIVPALAAGGHYDPGNTHHHLGPEGDGHMGDLPRLSANADGKVSETVVAPHLKKLAEIKQRSLMVHVGGDNYSDKPEPLGGGGARFACGVIE
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MT_SYNSP
Sequence: TSTTLVKCACEPCLCNVDPSKAIDRNGLYYCCEACADGHTGGSKGCGHTGCNC
What is the function of this protein?
This protein complexes cadmium, zinc and copper.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 14 family.
Protein: HOA2_MYCSS
Sequence: MTETVSRPHATEGAALYIQDVTLRDGMHAMRHRISPEKVAAIAGALDTAGVDAIEVTHGDGLAGHSLTYGPGSNTDWEWIEAAADVVHRAKLTTLLLPGVGTVRELEHAYKLGVTSVRVATHCTEADVSAQHIGTARELGMDVSGFLMMSHLAEPSHLAAQAKLMESYGAHCVYVTDSGGRLTMGSVRDRVRAYRDVLDAGTQIGIHAHQNLSLSVANTVVAVEEGVTRVDASLAGHGAGAGNCPIEPFIAVADLHGWKHNCDLFGLQDAADDIVRPLQDRPVQVDRETLTLGYAGVYSSFLRHAEAAAKQYGLDTRAILLAVGERGLVGGQEDLIPDIALDLQQNLRR
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 2, HOA 2, 4-hydroxy-2-keto-pentanoic acid aldolase 2, 4-hydroxy-2-oxopentanoate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: PITX1_MOUSE
Sequence: MDAFKGGMSLERLPEGLRPPPPPPHDMGPSFHLARAADPREPLENSASESSDADLPDKERGGEAKGPEDGGAGSAGCGGGAEDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQYNS
What is the function of this protein?
Sequence-specific transcription factor that binds gene promoters and activates their transcription.  May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.  Can independently activate and synergize with PIT-1 on pituitary-specific target gene promoters, thus may subserve functions in generating both precursor and specific cell phenotypes in the anterior pituitary gland and in several other organs.  Can activate pituitary transcription of the proopiomelanocortin gene.
What are the official names of this protein?
Pituitary homeobox 1, Hindlimb-expressed homeobox protein backfoot, Homeobox protein P-OTX, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1, Pituitary OTX-related factor.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIPB_BURMA
Sequence: MPVTVRWLGETPYDACFDAMRAFTDARTPDTDDEIWVVEHPPVYTLGQAGNPAHLLVADSGVPLVKVDRGGQITYHGPGQIVAYLLVDLRRRKLMVRTLVTRIEEAVIETLAAYNLASARKAGAPGIYVESGPHRGAKIAALGLKIRNGCSYHGLSVNVKMDLRPFLAINPCGYAGLETIDMASLGATADWHEVAQTLVRRLIAHLDGATAAAALPQQALEQSND
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_PSEAB
Sequence: MLVIHQRLPARSPRWDEELHLTYEARSKSRLRCFAASGEEVGLFLERGQPPLADGDCLEARDGRLVRVVARPERLLHVTCASPLELTRAAYHLGNRHVALQVGDGWLRLLDDYVLKAMLEQLGATVEAIEAPFQPEHGAYGGGHHHSHHGEAEFNYAPRLHQFGVRR
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBHL_ECOLI
Sequence: MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVITNAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDNANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSPGYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVKIHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQSIITRTADFINNVMIPDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNVLPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLGRILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAPRGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEILRTLHSFDPCLACSTHVLGDDGSELISVQVR
What is the function of this protein?
This is one of three E. coli hydrogenases synthesized in response to different physiological conditions.  HYD1 is believed to have a role in hydrogen cycling during fermentative growth.
What are the official names of this protein?
Hydrogenase-1 large chain, HYD1, Membrane-bound hydrogenase 1 large subunit, NiFe hydrogenase.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL28_STRP1
Sequence: MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKPKKVWASARALKSGKVERI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: YFJP_BACSU
Sequence: MWKEKVSVTPPYHFDRVLDRLSLDPLNAVDREAREVRVPIRNQAGDVCIVKVQALGHAGEPEFLVSGETDQGEMMKEIKRIFQWENHLQHVLDHFSKTSLSAIFEEHAGTPLVLDYSVYNCMMKCIIHQQLNLSFAYTLTERFVHAFGEQKDGVWCYPKPETIAELDYQDLRDLQFSMRKAEYTIDTSRMIAEGTLSLSELPHMADEDIMKKLIKIRGIGPWTVQNVLMFGLGRPNLFPLADIGLQNAIKRHFQLDDKPAKDVMLAMSKEWEPYLSYASLYLWRSIE
What is the function of this protein?
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2-methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions.
What are the official names of this protein?
Putative DNA-3-methyladenine glycosylase YfjP.
What is the protein family that this protein belongs to?
Belongs to the alkylbase DNA glycosidase AlkA family.
Protein: GATB_YEAS6
Sequence: MLQLARFYSLARTKAIHSHGAPFRPEYALKCGLEIHTQLNTKNKLFSQSTNSATSLVDAPNHHTSYYDIALPGTQPVLNLEAILFAMKLSLALGSQVNSISQFDRKHYFYGDQPQGYQLTQHYRPFARGGKINLSKELDDIDESAKEIGILQLQIEQDTGKSHYTETDKDVITLVDLNRSNVPLIELVTKPDFSDIKQVRAFIKKYQNLVRHLHISSGDLETGAMRVDVNLSINEYARVELKNLPNTSSIINAIKYEYQRQVELISVGDTSSLMEPETRGWTGSSTVKLRSKETTIDYRYMPDPELPYINLAQDVISGVRGLMPQLPDDIMRMLMKKPYQLSLKDAKILTYNSNQNDMYNHEALRSYYLDTFREFSKLAGERSNAKLPTNWIIHEFLGDLNKLQIPLARAKEILPPPVFAQFLKLLHEEVISATSGKMLLFHILENFKQSNCQDLSIPDFSKLIEKFELHAINQVDPQELMDLCNDVIAQHTDDTFIRNLVTGKKKSSLKFLIGQGMRRSQGRIKANEFEKKFKEILNIQW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CLPB_STAEQ
Sequence: MDINQMTYAVQGALQKAVAYSKEYELQNIEVEALLKAAMNENDSLFKSILERANIDVDQLIKAYDNQLSHYPTVQGDNVQYGQYISAKTNELLDKAEKYMKSYEDEFISMEHILRAAIDTDETTQKWVGNKVEVIKEIITKVRGGNHVTSQNPEVNYEALEKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPESLLDKTIFELDLSALVAGAKYRGEFEERLKAVLKEVKESEGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYREYIEKDSALERRFQKVGVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATIRTEMGSNPTELDQVNRRVMQLEIEESALKNESDNPSKHRLEELQEELSNEKEKQSSLKSRVEQEKEKIAKVQEKRAELDSSRQALEDAQTEGNLEKAAELQYGTIPQLEKELQKFEEAFQDETGEDSERMIREVVSDEEIGDIVSQWTGIPVSKLVETEREKLLSLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLASSLFDSEKHMIRIDMSEYMEKHAVSRLIGAPPGYVGHDEGGQLTEAVRRNPYSVILLDEVEKAHSDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIMTSNIGSQVLLENVKDAGEISDDTEKAVMDSLHAYFKPEILNRMDDIVLFKPLSVNDMSMIVDKILTQLNMRLLDQHISIEVTEEAKKWLGEEAYEPQFGARPLKRFVQRQIETPIARMMIKESLPEGTIIKVDLNDNKELDFKVVKPTS
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IES6_SCHPO
Sequence: MEKNSSVDSLDISLLARPFRNPNYKAQPRRNRNLRQIIQNDPVQNEPSKFSYSSIEAPPSVLPQPKYCDVTGLLAIYTDPKTRLRYHNKEIYGLIRELPSGADQEYLKLRSSDVVLK
What is the function of this protein?
Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.  Also involved in the regulation of telomere length (By similarity).
What are the official names of this protein?
Chromatin-remodeling complex subunit ies6.
What is the protein family that this protein belongs to?
Belongs to the IES6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_DESAL
Sequence: MVKISMKELLEAGVHFGHQTKRWNPKMKPYIFGARNGIYIVDLQKTVRMFRTACEFVSDVVANGGSVLFVGTKKQAREAVYEEANRAEAYYVHNRWLGGMLTNFQTIKKGIDRLNYLNEIKLNETINLFPKKERLKLEKERVKLDANLGGIRTMTKLPSVIFIIDPKNEAIAVREAKRLNIPTVAVVDTNCDPDDIDYVIPGNDDAIRAIRLLTSRIAEAVVQGKQIAAERRAAEQDKAADDKAQEQAAAEAAKPEPAAPAPAAEAAEEAPAEEGPIIEVIKKSGSEEDGEAAN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.