PharMolix/UniProtQA huggingface dataset:
Protein: DPH2_KLULA
Sequence: MNDSVLVAPSLSTAQTEDTFEFQSYGETEHSRSYLGSDVTKDNLVELVSAYYSVPELIQYFEEHPQYKKITLQFPDELVLDSSIVVQLMQQELVKAEDETSQSFNTIDTDEVLHNEKSCGNCSGCDCSSKIDKTETKRKVWILADTSYSSCCVDEVASEHVKGDIVVHFGDACMNAVQKLPVVYSLGRPVLDLDLVVSQFKLKYAAKDQKICLMADAPHSMHMKSIYDILHDKEGYKNVVYSDINQDMLQSDTHIVGYNNAVEHDERLRKCVTCGNRNIYAEVDVSELNEYDLFHVTIPKDPHLLYLTTKFQSVTLYDPSSGMLNEGPFPSMMKRYKFMHMARTAGTIGILVNTLSLRNTKETMNKLTKLLKENGKKHYLFVVGKPNVAKLANFEPIDIWCILGCGQGGIVLDQYNEFYKPIITPYELLMALSDEVTWTGQWITDFKSIINQIENEVNDSDDMEQDILSSGTECRSDEDEAPEFNAVTGKYVSTSRPLRQIARLEIETPVEEVRASDSTELVKQFSQTVAIRNTVSTSAAFLQTRHWTGLGSDYKDDEDGEEDGATVEEGTAGVARSYQFDELNKKT
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1 (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_STRAW
Sequence: MIDLNADLGEGFGRWELTDDERLLSVVTSANVACGFHAGDAATMRRVCELAAERGVRIGAQVSYRDLAGFGRRAMDVPPAELAAEVAYQIGALEVFARAAGTRVSYVKPHGALYNRVVHDEGQAGAVVDGVRLADASLPVLGLPGSRLLEVAEKAGLPVVTEAFADRAYTEEGTLVPRGEDGAVVTDPDAVVERSVNLARLGVVDAHSGRRIPVRARSLCLHGDTPGAVELARRVRSRLEASGVRVAAFA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: RL30_SOLM1
Sequence: MANITVKLVRSRYGNTPKQRATLASLGLKKIRQERSFEKTDTLVGMIAKVQHLVEVTES
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: MAEL_PIG
Sequence: MPNRRGSRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREEEKEKYSEMAREWKAAQGKDAGPWEKQKPVSTPLRRPAMLVPKQNVSPPDMSCLSLKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISHFESGHDQATVLQNLYRFIRPNSGKWPPIYCKSDDRARVNWCLKYMAKSSEITQDLELVTVEDLVVGIYQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCRKIAYCISNSLATLLGIQLTEAHVPLQDYETSNSVTPKMVVLDAGRYQKLRVESSGFSHFSSSNQEQRSNTPTGDYPSGVKISGQSSSVRGRGITRLLESISNSSSNIHKFSTCESSLSPYMSQKDGYKSFSSLS
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process.  Required for the localization of germ-cell factors to the meiotic nuage (By similarity).
What are the official names of this protein?
Protein maelstrom homolog.
What is the protein family that this protein belongs to?
Belongs to the maelstrom family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to piP-bodies, a subset of the nuage which contains secondary piRNAs (By similarity).
Protein: Y1677_STRCO
Sequence: MPTPPCPCGRSESYEKCCGRFHGGTAAAPTAEALMRSRYCAFVQGDASYLLRTWHPRTRPARLDLDPGMRWTGLEILDTADGSAFHTTGTVTFRASYRGGSLHERSRFERVDGAWVYADGEFLD
What are the official names of this protein?
UPF0225 protein SCO1677.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: NOP16_COCIM
Sequence: MGRVLQKKKNRSSAPKIKIKSGKSKSGKKKINVLGNSIIAQNWDKKLTLAQNYRRLGLATRLNAPTGGVEKGVSAGALNNISSLATKGKTAAQIQPSEARVERDPETGKILRIIQPDQAGDDGTIEVAGHKRRRTNPLDDPLNELSDVEDSTLRDTGASTDVVSALERQAAAEEERVKKRKPRHQSKREEEWLQRLVDKYGDDVPAMVRDRKLNPMQQTEGDIRRRLRKWHGNKK
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Nucleolar protein 16.
What is the protein family that this protein belongs to?
Belongs to the NOP16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: KAE1_NANEQ
Sequence: MKVLGIECTAHTFGVGIFDSEKGVLANEKVTYKGYGIHPREAAELHLKEFDKVLLKALEKANISLKDIDLIAVSSGPGLLPTLKLGNYIAVYLGKKLNKPVIGVNHIVAHNEFARYLAKAKDPLFVYVSGANTQFLAIVNNSWFLVGETLDMGVGNLIDKVARDLGLEFPGGPKIEELAKKGKNLIELPYTIKGLNLQLGGIYTYIKRIKDQYSKEDIAYSLQEWVFALILEIAERAMHMLDKKELILTGGVACNNRLNDMAEQMAKENNFKFYRLPCQYLTDNGAMIAYLGYYWYSQGIYYEPKPRPYWRIWI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_BACC7
Sequence: MVINFEELHPNERAELERNIFFSTLEQLKGWARSNSLWPMTFGLACCAIEMMGVGSSHYDLDRFGSFFRTSPRQSDVMIVSGTVTKKMAPIVRRLYDQMPEPKWVIAMGSCATAGGPYVNSYAVVKGVDQIVPVDVYIPGCPPNPAALIYGINKLKEKIRYEAKTGKQVTNK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HN_PI3B
Sequence: MEYWKHTNSTKDTNNELGTTRDRHSSKATNIIMYIFWTTTSTILSVIFIMILINLIQENNHNKLMLQEIRKEFAAIDTKIQKTSDDIGTSIQSGINTRLLTIQSHVQNYIPLSLTQQMSDLRKFINDLTTKREHQEVPIQRMTHDSGIEPLNPDKFWRCTSGNPSLTSSPKIRLIPGPGLLATSTTVNGCIRLPSLAINNLIYAYTSNLITQGCQDIGKSYQVLQIGIITINSDLVPDLNPRVTHTFNIDDNRKSCSLALLNTDVYQLCSTPKVDERSDYASTGIEDIVLDIVTSNGLIITTRFTNNNITFDKPYAALYPSVGPGIYYKDKVIFLGYGGLEHEENGDVICNTTGCPGKTQRDCNQASYSPWFSNRRMVNSIIVVDKGIDTTFSLRVWTIPMRQNYWGSEGRLLLLGDRIYIYTRSTSWHSKLQLGVIDISDFNNIRINWTWHNVLSRPGNDECPWGHSCPDGCITGVYTDAYPLNPSGSIVSSVILDSQKSRENPIITYSTATNRVNELAIYNRTLPAAYTTTNCITHYDKGYCFHIVEINHRSLNTFQPMLFKTEVPKNCS
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: DAD1_SCHPO
Sequence: MSSENMDITENIQNEQNKDFDDIDFERRRRLLTLQISKSMNEVVNLMSALNKNLESINGVGKEFENVASLWKEFQNSVLQKKDREMLDAP
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore.  Mediates interaction between the DASH and sim4 complexes leading to loading of DASH onto the kinetochore.
What are the official names of this protein?
DASH complex subunit dad1, Outer kinetochore protein dad1.
What is the protein family that this protein belongs to?
Belongs to the DASH complex DAD1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore. Unlike the other DASH complex members, dad1 remains associated with the kinetochore throughout the cell cycle.
Protein: RECA_SYNP6
Sequence: MASKSDAIAPEKEKALNLVLSQIERNFGKGAIMRLGDAARLRVETISTGALTLDLALGGGLPKGRIIEVYGPESSGKTTLTLHAIAEVQKQGGIAAFVDAEHALDPVYATSVGVDIDNLLISQPDTGEMALEIVDQLVRSAAVDIVVIDSVAALVPRAEIEGEMGDAQVGLQARLMSQAMRKITGNIGKSGCTVIFLNQLRQKIGVTYGSPETTTGGQALKFYASVRLDIRRIQTLKKGTEEYGTRAKVKVVKNKVAPPFRIAEFDILFGKGISTLGCLVDLAEETGVILRKGAWYSYNGDNIGQGRDNTITHLEEHPDFRATVEQQVREKLALGAQVSANTVGAAPAKTAEDTDS
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_PSEFL
Sequence: MDDNKKKALAAALGQIERQFGKGAVMRMGDHDRQAIPAISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAQAQKMGATCAFVDAEHALDPEYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAIDVIVVDSVAALVPKAEIEGEMGDMHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYGKGIYLNGEMIDLGVLHGFVEKSGAWYAYNGSKIGQGKANSAKFLADNPDIVATLEKQIRDKLLTPAPDVKAAANREPVEEVEEADTDI
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_THISH
Sequence: MYAVIATGGKQYRVAQGDVLRVEKLDAEAGATVEFDNVLLVGSGDDVKVGTPNVEGGKVTATVKAHGRGEKVMIIKFRRRKHHRKQMGHRQDFTEVEITGISG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GDF8_PANTR
Sequence: MQKLQLCVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS
What is the function of this protein?
Acts specifically as a negative regulator of skeletal muscle growth.
What are the official names of this protein?
Growth/differentiation factor 8, GDF-8, Myostatin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RRF_CYTH3
Sequence: MEEINLYLDDAKDSMQKAIKHTELELSKIRAGKASPNMFDGIMVDYYGSSTPLAQVATVSVPEPRSITIKAYEKSMVTTIEKAIRDANMGFNPQNDGDVIRINVPPLTEERRRDLVKQTKAEGESGKVRIRKIRQETNDELKKLLKDGASEDEVKRAEEVVQALTNDTSAKLEALIAAKEKELMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTCD_HUMAN
Sequence: MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSRDSSLLRDDLIQDVEIQIISRQELPPIVQNCCLPAVVERSDNFCRAGLAVVLRHIIQKSYEADPLKKELLELLGFKKTCLKACAEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGGPRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNIWFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFPKSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQVISMEPESCSPKNNMIVGVPI
What are the official names of this protein?
Glutathione S-transferase C-terminal domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the GSTCD family.
Protein: RSMG_STAAR
Sequence: MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNYLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_DEHMB
Sequence: MGRKVHPIGFRLGIIKDWSAKWHASDKNFAECLTEDLKLRKAISKKYVDAAISQVDIERQSNKVTVSVRTARPGIVIGRGGQRVDEMRHFLEDLIGKKVQLNIVEISQAELDAFLVARSVAEQIERRVAYRRAMKQAIFRSMQAGAKGIKICASGRLGGVEIARREVMHEGRVPLHTLRADIDYGCTRAHTALGDVGIKVWVYRGDILPEAKEKSESAVTEMAAVMADAPAAVVTETKVADIAAKPKRVVKKAEAEIPAEEKPKRVVKKAENITKEEE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SP87_DICDI
Sequence: MLFLKNIGVFFMIFLVSKSYATDCNKITNEEECHKSSECIVINYTPCCGEQKWACSKGTFDTCTYENSCYRNSSNNQVVEVSNKCFNLDGFIKITTPTEYSCSDAKIKECALLGKSCSFQKNSCSNPTSCCPGESICEGLSSGSSTSGGGSSGGTSGGSSSGGTSGGSSSGGTSGSSSSGSSSGGVSSCSTTHCPEGYHCSMVNDVATCLASTTGGTGLPGTSSSTAGVSSCLTTLCPIGHICVEDSNGVNCVPNGGGTSGGSSSTGTSGGHPDPCRDVDCPDGFHCECKDGKTAKCVPSPTTGSSSTSGGHPDPCKDVTCPDGFHCECKDGKTAKCVPSPTTGSSSTSGGNTNPCSNVNCPDGFYCECKDGKTAKCVPSGPTQPPKPPVCSLRCPPNHECRFNDQGHQCCVKVHHDRCSLRCPHGHECKVDHNGKECCVRSHRPPPPEVCSLRCPPKHECKFDDHGKKCCVKIHCDEVCDLDCGRGFECKIRHDGSKCCVRSERPHPPQHEKCNKRCPPGHECKVDQHGKECCVVAHRPPPKCSLRCPPRHECRVNHFGEECCVKVHHDKCSLRCPPGHECKVDQHGKECCVVAHRPPPKCSLRCPPKHECRINHFGEECCVKSRNDCLTCEDLNCERKGLHCAMKTVPIDKENCCEKVPVCYSTNPLLDGGHGFI
What is the function of this protein?
May contribute to the structure of the coat at the interface between the middle, cellulosic layer and the outer, electron-dense, proteinaceous layer.
What are the official names of this protein?
Spore coat protein SP87, Protein PL3.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Spore coat. Note=Accumulates specifically in regulated secretory vesicles of prespore cells (prespore vesicles). The protein later accumulates extracellularly in the spore coat.
Protein: HSLV_SALTI
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELGAREIAEKALDIAGDICIYTNHFHTIEELTAKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CECD_HYACE
Sequence: MNFTKILFFVVACVFAMRTVSAAPWNPFKELEKVGQRVRDAVISAGPAVATVAQATALAKGK
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-D.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMN_SALG2
Sequence: MSEQIVTPESSTPVVLNNETKINLLDLNRQQMREFFKNLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLTNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDTIRDEIVPINKKYNIETFLGAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKETPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEVIDIKAI
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCOP5_ARATH
Sequence: MATKTSNFVSLRVSLFILLLFISSQVAIADAKHLQQLRRKLQIVRRSRSQRGRQYNPPTLRVPPPPPPPLPQMPSAATPPPMPQLSPLQPKMHVSSLQPQMLYPPPSLPYASSPTST
What is the function of this protein?
Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation.
What are the official names of this protein?
Serine rich endogenous peptide 5, AtSCOOP5, Phytocytokine SCOOP5, Precursor of serine rich endogenous peptide phytocytokine 5.
Protein: PUR9_SYNS3
Sequence: MAPTALLSVSDKRGVVPLAEALHRLHGYQLLSSGGTAKVLQEAGLPVTRVADHTGAPEILGGRVKTLHPRIHGGILARRGDPAHEADLLEQQIDPIDVVVVNLYPFRETVATPDVSWDAAIENIDIGGPTMVRSAAKNHAHVAVLTSPEQYDRFLKALSGSAGGVNANVRRQLALEAFAHTAAYDVAISRWMQSRPELQPDVEAAAPAEALPWLEALPLRQTLRYGENPHQKAAWFSSPMGWGGAKQLQGKALSTNNLLDLEAALATVREFGYGSSGLHPAQQAAAVVVKHTNPCGVAVGDGVGIALTRALDGDRISAFGGIVALNAVVDGPAAKELTSLFLECVVAPGYSSEALEILAAKGNLRLLELPPEAIDAAPKDHVRSILGGVLVQDLDDQPIDPSAWTVASQRQPTTAETADLRFAWQLVRHVRSNAILVARDGQSLGVGAGQMNRVGSARIALEAAGEQAVGAVLASDGFFPFDDTVRLAASHGIKAVIHPGGSLRDADSIKACDELGLAMVLTGRRHFLH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: YDDJ_BACSU
Sequence: MKNLFIFLSLMMMFVLTACGGSKYDDAIDDVISQYKEHKGNDTEINIKRENAIVRVYEGGKYIQFAFYMPDNSSRELTTFKYYEKFGDKYEKMTDMPGNGENDRLGLSKKTPDYEEVKGEETELEE
What are the official names of this protein?
Uncharacterized protein YddJ.
Protein: ASTE_ECOBW
Sequence: MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQGALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDMNRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPQFGVLPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFGQNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFMPFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: VLDLR_RABIT
Sequence: MGTSARRALWLLLALCWALRESGATATGRKTKCEASQFQCTNGRCITQLWKCDGDEDCVDGSDEKNCVKKTCAESDFVCNNGQCIPNRWQCDGDPDCEDGSDESPEQCHMRTCRINEISCGARSTQCIPVSWRCDGESDCDSGEDEENCGNVTCSSDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHVNECLVNNGGCSHICKDSVIGYECDCAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADVSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASRTISVATLDGAKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTVDIQWPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGSELATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINEHSPKYTCSCPNGYHLEENGRECQSTATTVTYSETKDTNTTEISPTSGLVPGEINVTTAVSEVSVPPKGTSAAWAILPLLLLAMAAVGGYLMWRNWQHKNMKSMNFDNPVYLKTTEEDLSIDIGRHSASVGHTYPAISVVSTDDDLA
What is the function of this protein?
Multifunctional cell surface receptor that binds VLDL and transports it into cells by endocytosis and therefore plays an important role in energy metabolism.  Binds also to a wide range of other molecules including Reelin/RELN or apolipoprotein E/APOE-containing ligands as well as clusterin/CLU.  In the off-state of the pathway, forms homooligomers or heterooligomers with LRP8.  Upon binding to ligands, homooligomers are rearranged to higher order receptor clusters that transmit the extracellular RELN signal to intracellular signaling processes by binding to DAB1 (By similarity).  This interaction results in phosphorylation of DAB1 leading to the ultimate cell responses required for the correct positioning of newly generated neurons.  Later, mediates a stop signal for migrating neurons, preventing them from entering the marginal zone (By similarity).
What are the official names of this protein?
Very low-density lipoprotein receptor, VLDL receptor, VLDL-R.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein.
Protein: BGLS_TRIRP
Sequence: MDFIVAIFALFVISSFTITSTNAVEASTLLDIGNLSRSSFPRGFIFGAGSSAYQFEGAVNEGGRGPSIWDTFTHKYPEKIRDGSNADITVDQYHRYKEDVGIMKDQNMDSYRFSISWPRILPKGKLSGGINHEGIKYYNNLINELLANGIQPFVTLFHWDLPQVLEDEYGGFLNSGVINDFRDYTDLCFKEFGDRVRYWSTLNEPWVFSNSGYALGTNAPGRCSASNVAKPGDSGTGPYIVTHNQILAHAEAVHVYKTKYQAYQKGKIGITLVSNWLMPLDDNSIPDIKAAERSLDFQFGLFMEQLTTGDYSKSMRRIVKNRLPKFSKFESSLVNGSFDFIGINYYSSSYISNAPSHGNAKPSYSTNPMTNISFEKHGIPLGPRAASIWIYVYPYMFIQEDFEIFCYILKINITILQFSITENGMNEFNDATLPVEEALLNTYRIDYYYRHLYYIRSAIRAGSNVKGFYAWSFLDCNEWFAGFTVRFGLNFVD
What are the official names of this protein?
Non-cyanogenic beta-glucosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: Y604_STAES
Sequence: MAEDKFEQAKGNIKETVGNATDNKELEKDGKGDKASGKAKEAVENVKEKANDVIDKFKGNKGD
What are the official names of this protein?
UPF0337 protein SE_0604.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.