PharMolix/UniProtQA huggingface dataset:
Protein: CYT1_ORYSJ
Sequence: MRKYRVAGLVAALLVLHSLATPSAQAEAHRAGGEGEEKMSSDGGPVLGGVEPVGNENDLHLVDLARFAVTEHNKKANSLLEFEKLVSVKQQVVAGTLYYFTIEVKEGDAKKLYEAKVWEKPWMDFKELQEFKPVDASANA
What is the function of this protein?
There are two distinct cystatins in rice seeds (Oryzacystatin-1 and -2) with different specificities against cysteine proteinases.  May be involved in the control of germination by inhibition of endogenous cysteine proteinases.  May play a role in defense by inhibiting exogenous proteases such as those present in digestive tracks of insects and nematodes.
What are the official names of this protein?
Cysteine proteinase inhibitor 1, Oryzacystatin I, OC-I, Oryzacystatin-1, OsCP1, SPOC-I.
What is the protein family that this protein belongs to?
Belongs to the cystatin family. Phytocystatin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3_ALTPJ
Sequence: MGQKTNPNGLRLGIIRSWESKWYANEKDVPALINEDYNIRKYLNKVYKKAGVSQIEIERLKGKAKDRIKVTLYTAKPGIVIGRDGETRNKAVSELEYLTKKEIVFNVVEVKRPEKVAELVAQNMAEQLENRASFRRVQKIAIQRALKSGAKGVKTLVSGRLGGAEMARSEGYSEGRVPLHTLRADVDYATAEAHTTYGVLGIKVWVFHGEVLPGQTILDTRKPFEASAPRPQRRNRKEANNYVNAKKN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PSB1_HUMAN
Sequence: MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD
What is the function of this protein?
Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit beta type-1, Macropain subunit C5, Multicatalytic endopeptidase complex subunit C5, Proteasome component C5, Proteasome gamma chain.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9.
Protein: SYI_AERHH
Sequence: MSDYKHTLNLPETEFPMRGDLAKREPNMLKRWYDQDLYGAIRRAKAGKPSFILHDGPPYANGSIHIGHSVNKILKDIIIKSKGLSGFDSPYVPGWDCHGLPIELKVEGMVGKPGEKVSAAEFRAECRKYAKTQIEAQKTDFIRLGVLGDWEHPYLTMDFGTEANIIRSMAKIVENGHLHKGSKPVHWCTDCGSALAEAEVEYYDKNSPSIDVRFKAVDEAGVAAKFDCAEGHTGKGPISAVIWTTTPWTLPANRGIAMHADLDYALVQVEGEHPERLILAAELVKDVMDRAGIEQFHNLGYAKGAALELLRFNHPFYSFDVPVVLGDHVTLDAGTGAVHTAPGHGQEDFVVGQKYGLEVANPVGSNGVYLPDTELFAGQHVFKANASVVEVLTERGALLHHKVFNHSYPHCWRHKTPIIFRATPQWFISMEQKGLRQRALEEIERIEQDGIKQHGQSGWVPAWGKNRIQAMVENRPDWCISRQRTWGVPISLFVHKETQELHPESVRLMHEVAKRVEQSGIQAWWDLDKAELLGSDADLYDKVPDTLDVWFDSGSTHSSVVDARPEFNGNPADMYLEGSDQHRGWFMSSLMIGVAMKDKAPYNQVLTHGFTVDGQGRKMSKSIGNVVSPQDVMNKLGADILRLWVASTDYTGEMTVSDEILKRSADAYRRIRNTARFLLANLNGFNPATDMVAPADMVVVDRWAVGRAKAVQAEIMAAFDEYNFHGVTQKLMQFCSIEMGSFYLDVIKDRQYTAKADSLARRSCQTALYHIAEAMVRWMAPIMSFTADEIWALLPGERGEFVFTEEWYDGLFGLEAGETLNDDFWAEILTVRGEVNKALEVARGEKRIGGSLQAELTLFAKPALAARLNALADELRFVLLTSKAKVVSVDAAPADAVATERDDLWLSVAQSAAAKCDRCWHHVEDVGTIAGHEEICGRCVTNVEGDGETRQFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMF_SHELP
Sequence: MVQLNQNFINSIAKDMPDHLSMDEFISYCAKPLRPSIRVNTLKITTADFITMMNAKGWQFEPVPWCEDGFWVKVDDSVQLGNTVEHIQGLFYIQEASSMLPPKALFPEPIEDATSLTLLDMASAPGSKTTQLAAMMNNQGLLVANEYSSSRVKVLHANVQRMGASNLALTHFDARVFGKYLFESFDAILLDAPCGGEGTVRKDPDALKHWDESEIEAIASVQRDLIESAFLALKPGGSLVYSTCTLNRRENQDVCLHLKATYGDAVQFESLAGLFPGAEKASTSEGFLHVWPQIFDSEGFFIAKLTKIAAVPRNSEEPRKQKNFPFTPIDKKSRQALCDYFDTSFGIKLDGQGILMQRDDEFWLFPTNVDPLIGKIRFQRIGLKLADALKKGFKPRHEAVMALADRLRGIPLDEAQAIQYLMGRDIALTSKEKPQGERLVSYQGAHLGLVKHLGNKLKNSLPRDLVRDKICSSSAMAVDQQATGED
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRCA_EMENI
Sequence: MSTNPRFDPNFTPYVINSMGPKTPERARVILGSLIRHIHDFAREVELTPAEWMLGVEFINSIGKISTPIRNECHRICDVIGLESLVDEIANRIVTEQGLSPTSNVILGPFWSPNAPFRELGDSIIQDPNPNGKVTFMHGVLRDMETGAPIAGAVLDIWQASANGQYDFQDPNQSENNLRGKFRSNEKGEFYWYCYHPTPYSLPTDGPAGVLLNLMDRSPMRPAHIHLMITHPDYATVINQIYPSDDPHLDIDSVFAVKDDLVVDFKPKTDDPKAELDLEYNVKMALKKHHPNPNSAPPVSSFERYNKAGKEKL
What is the function of this protein?
Intradiol ring-cleavage dioxygenase; part of the benzoic acid degradation pathway also known as the protocatechuic acid pathway (PubMed:25479309).  Benzoic acid debradation begins with the conversion of benzoic acid into 4-hydroxybenzoic acid through hydroxylation by the benzoate-4-monooxygenase bphA, and its partner NADPH-cytochrome P450 reductase cprA which act as a mediator in electron donation from NADPH (By similarity).  4-Hydroxybenzoic acid is then converted into 3,4-dihydroxybenzoic acid (also called protocatechuic acid) by the p-hydroxybenzoate-m-hydroxylase phhA (Probable).  Protocatechuic acid is converted into 3-carboxy-cis,cis-muconic acid by the intradiol ring-cleavage dioxygenase prcA, which is further metabolized through the 3-oxoadipate pathway to finally enter the tricarboxylic acid cycle (TCA) (Probable).
What are the official names of this protein?
Intradiol ring-cleavage dioxygenase prcA, Protocatechuate 3,4-dioxygenase A.
What is the protein family that this protein belongs to?
Belongs to the intradiol ring-cleavage dioxygenase family.
Protein: DUT_NEIMA
Sequence: MNIEVEMKVLDERMADVVPVYATKGSAGLDLRACLDEEVVLQPGETFLVPTGLAIYLADPSYAAVLLPRSGLGHKHGIVLGNLVGLIDSDYQGELKVSLWNRSSEPFTVKPFERIAQMVIVPIVQARFKRVEEFVGSSRGEGGFGSTGLH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: SAHH_RHOPS
Sequence: MTAKFTDYIVKDIGLAEFGRKEISLAETEMPGLMATREEYGPKQPLKGARIAGSLHMTIQTAVLIETLTALGADVRWVSCNIYSTQDHAAAAIAAAGIPVFAIKGESLEDYWDYTARMFDWHGGGTPNMILDDGGDATMYVHLGLRAENGDTAFLDKPGSDEEVIFFALLKKQLKEKPKGYFAEIAKNIRGVSEETTTGVHRLYDMQKAGTLLWPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMMSGKVAMVAGFGDVGKGSAASLRQAGARVMVSEVDPICALQAAMEGYQVVTMEDAAPIADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQIAHLKNLKWDNIKPQVDEITFPDGKRMILLSEGRLVNLGNATGHPSFVMSASFTNQTLAQIELFANNKDGKYKKEVYVLPKSLDEKVARLHLAKIGVKLTELRKDQADYIGVKVEGPFKADHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATI_AERPE
Sequence: MLLPRMLEEVVLAVPARDYDRVVAGLAVEGIFHVDSPPQGVKGEVDRSYRALLTQASERSSRIRQYFDLAGVEPYRVSGVEIEVGGWGESWKRYLEKYSGVEKFYSGLLEEYSEAEARLKELLDIEARIAPVAHLDVDIARLYRSGAFDFAVYYGSYSEGLESRVGEIVSRVGGLAAVEASGGSVVVAVAVPKGALSKISPEILRLNLSIYTPPEGVPGSPREAMEYIRGEKARLGRRLVSIQEMASERLGELAEFYTVVTAFENIFKFLVSTLRRGETRIVRGFVDVRDSGRLRSIVDRMTRGSYVLLSLGVRRGGEAPIPSKVDLPQFLKPFSRVVELYGYPEPNEIVPTVFLAITLPLTFALMFPDAGQGLLVLLFSLFYLRRVSRDWAYVIAVMGGASVVSGLLAGEVFGPLVSKMLGLPELWYRLGLETPPYAMPTYAIDHGEEELVPVLVYRALNVSLFMGAFMLSFGTFLGVVNGVIKRDWVGLVESRLPRFLLFASITGPFLVYMDAGEAGSVLRQALLELGGDSIAAKLVLAGSVLGLAWMLLAGPIIYMLEGHSPLAGLANSFLEAYESLLMLVGNIPSFLRIMALALAHSSLMFVIYYLTVMIMQGGILADVVGALLYVGGNLAVAAMEGLLAFAHASRLHFYEWFSKFYSGTGVPYTPIKVEGVRIKIAGQTF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit I, V-ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LALBA_MOUSE
Sequence: MMHFVPLFLVCILSLPAFQATELTKCKVSHAIKDIDGYQGISLLEWACVLFHTSGYDTQAVVNDNGSTEYGLFQISDRFWCKSSEFPESENICGISCDKLLDDELDDDIACAKKILAIKGIDYWKAYKPMCSEKLEQWRCEKP
What is the function of this protein?
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme.  This enables LS to synthesize lactose, the major carbohydrate component of milk.  In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
What are the official names of this protein?
Alpha-lactalbumin, Lactose synthase B protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYP_LACP7
Sequence: MANDKKLVESITSMDEDFAQWYTDVVKKAELVDYSGVRGCTIFRPAGYAIWENIQKELDARFKATGVENVYMPMFIPESLLNKEKDHVEGFAPEVAWVTHGGGEQLQERLCVRPTSETLFCDFYSHIIESYRDLPKLYNQWCSVVRWEKTTRPFLRTLEFLWQEGHTAHATAEEAEERTIQMLNLYADFCEEVLAIPMVRGRKTDKEKFAGAEATYTIEALMHDGKALQSGTSHNFGDGFAKAFNIQYTDKENKLQYVHQTSWGMTTRLIGALIMVHGDNSGLVLPPRIAPTQVVIVPIMQKKEGVLEKAAELREKLGAFRVKVDDSDKSPGWKFSEHEMRGIPVRVEIGPKDIEANQAVLVRRDTREKTVVSLDEIDTKIGEILEAMQKEMLERARNHRDAHTYEAHSTEEFADVVANKPGFVKAMWCGERACEDEIKEKTGATSRCMPFAQEHIADTCVCCGKQAKSLVYWGKAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JUN_AVIS1
Sequence: MSAKMEPTFYEDALNASFAPPESGGYGYNNADILTSPDVGLLKLASPELERLIIQSSNGLITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHNQNTLPSVTSAAQPVSGGMAPVSSMAGGGSFNTSLHSEPPVYANLSNFNPNALNSAPNYNANRMGYAPQHHINPQMPVQHPRLQALKEEPQTVPEMPGETPPLFPIDMESQERIKAERKRMRNRIAASKSRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
What is the function of this protein?
This oncogene is the viral derivative of the AP-1 transcription factor.
What are the official names of this protein?
Viral jun-transforming protein, v-Jun.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Jun subfamily.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RLP33_ARATH
Sequence: MSLIPITFYFLFLFFSNFRGVFAVPNIHLCHFEQRDALLEFKNEFKIKKPCFGCPSPLKTKSWENGSDCCHWDGITCDAKTGEVIEIDLMCSCLHGWFHSNSNLSMLQNFHFLTTLDLSYNHLSGQISSSIGNLSHLTTLDLSGNNFSGWIPSSLGNLFHLTSLHLYDNNFGGEIPSSLGNLSYLTFLDLSTNNFVGEIPSSFGSLNQLSILRLDNNKLSGNLPLEVINLTKLSEISLSHNQFTGTLPPNITSLSILESFSASGNNFVGTIPSSLFTIPSITLIFLDNNQLSGTLEFGNISSPSNLLVLQLGGNNLRGPIPTSISRLVNLRTLDLSHFNIQGQVDFNIFSHLKLLGNLYLSHSNTTTTIDLNAVLSCFKMLISLDLSGNHVLVTNKSSVSDPPLGLIGSLNLSGCGITEFPDILRTQRQMRTLDISNNKIKGQVPSWLLLQLEYMHISNNNFIGFERSTKLEKTVVPKPSMKHFFGSNNNFSGKIPSFICSLRSLIILDLSNNNFSGAIPPCVGKFKSTLSDLNLRRNRLSGSLPKTIIKSLRSLDVSHNELEGKLPRSLIHFSTLEVLNVESNRINDTFPFWLSSLKKLQVLVLRSNAFHGRIHKTRFPKLRIIDISRNHFNGTLPSDCFVEWTGMHSLEKNEDRFNEKYMGSGYYHDSMVLMNKGLEMELVRILKIYTALDFSGNKFEGEIPRSIGLLKELHILNLSSNGFTGHIPSSMGNLRELESLDVSRNKLSGEIPQELGNLSYLAYMNFSHNQLVGQVPGGTQFRTQSASSFEENLGLCGRPLEECRVVHEPTPSGESETLESEQVLSWIAAAIGFTPGIVLGLTIGHIVLSSKPRWFFKVLYINNSRRRRRTRSEKS
What are the official names of this protein?
Receptor-like protein 33, AtRLP33.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: FMTA_STAAM
Sequence: MKFNKVKLVIHACVLLFIIISIALIFHRLQTKTHSIDPIHKETKLSDNEKYLVDRNKEKVAPSKLKEVYNSKDPKYKKIDKYLQSSLFNGSVAIYENGKLKMSKGYGYQDFEKGIKNTPNTMFLIGSAQKFSTGLLLKQLEEEHKININDPVSKYLPWFKTSKPIPLKDLMLHQSGLYKYKSSKDYKNLDQAVKAIQKRGIDPKKYKKHMYNDGNYLVLAKVIEEVTGKSYAENYYTKIGDPLKLQHTAFYDEQPFKKYLAKGYAYNSTGLSFLRPNILDQYYGAGNLYMTPTDMGKLITQIQQYKLFSPKITNPLLHEFGTKQYPDEYRYGFYAKPTLNRLNGGFFGQVFTVYYNDKYVVVLALNVKGNNEVRIKHIYNDILKQNKPYNTKGVIVQ
What is the function of this protein?
Catalyzes the liberation of D-alanyl moieties present on wall teichoic acid (WTA) and lipoteichoic acid (LTA) (PubMed:26861022).  Affects the methicillin resistance level and autolysis in the presence of Triton X-100 as well as the cell wall structure (PubMed:22564846).
What are the official names of this protein?
Teichoic acid D-alanine hydrolase, Teichoic acid D-alanine esterase.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NU6C_ORYSI
Sequence: MDLPGPIHEILVLFGGFVLLLGGLGVVLLTNPTFSAFSLGLVLVCISLFYILLNSYFVAVAQLLIYVGAINVLIIFAVMFVNGSEWSKDKNFWTIGDGFTSLVCITIPFSLMTTIPDTSWYGILWTTRSNQIVEQGLINNVQQIGIHLATDFYLPFELISIILLVSLIGAITMARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HIS3_PYRCJ
Sequence: MDAVPLATPEEAWRIAKSLNYRHIGGTVVAVVQDVETGEVLMVGHMDPVAVVLTLTTGLAHYYSTSRKRIWLKGETSGHYQIVKEFRTDCDGDAVVLKVVQIGAACHTGARSCFSSPASFKIRLNRDA
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCRI_BOVIN
Sequence: MLSVAARSGPFAPVLSATSRGVAGALRPLVQAAVPATSESPVLDLKRSVLCRESLRGQAAGRPLVASVSLNVPASVRYSHTDIKVPDFSDYRRPEVLDSTKSSKESSEARKGFSYLVTATTTVGVAYAAKNVVSQFVSSMSASADVLAMSKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTKKEIDQEAAVEVSQLRDPQHDLERVKKPEWVILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPSYEFTSDDMVIVG
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).  UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer.  One of the fragments, called subunit 9, corresponds to its mitochondrial targeting sequence (MTS) (PubMed:8386158, PubMed:2996928).  The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function (By similarity).
What are the official names of this protein?
Cytochrome b-c1 complex subunit Rieske, mitochondrial, Complex III subunit 5, Cytochrome b-c1 complex subunit 5, Rieske iron-sulfur protein, RISP, Rieske protein UQCRFS1, Ubiquinol-cytochrome c reductase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PVK1_DERAT
Sequence: GASGLIPVMRN
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, DerAt-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PALA_ASHGO
Sequence: MSQLSAVPLKMTLQVDMQAQLAAIIDSTFYQVSSVFIDDLAAVNDMRNRSLMEADASVSNLEALLEYCKTLFALIAKFPDRQIEFTWFETLGHKAYGKTSNLWKFELFNVIYNIGAVKSLLASSMGNDELKEACRYLQESAGCFQYILSAMERELESVIDEKTIRAVLNLMLAQAQECCWARALRDAMKHSPIARLALQVSNFYEEAHRYARISPVIRTKLVKYINEKSFYFAAVAHYRHALHFEEKQQYGNAVRSLNEAQEKIKGAGWGPEVLPFEKELNDTLNTLQRDNDLIYLQHIPSQCPVINPVSMVKPILIDLLSTGTQKIHLFRNLLPIDVIESSAAFNIRQDKYVEDYVKSPLVALNKLLHNSLPENEALPGMKHLTEEEFDIYAKTLAGLNEFSSQLGERLTVIKSLIDGATTRLPAEANHHADQDNSKDIVEEYNKRIVTLQGYLRQGEEITRETTQIFETVDRDLLTTQLQLAATNNPTMRKVEALTKERYDYIAEVEKKSLQNRILPSLVSNYKETGSLDFEPIFQEHLKMFKKDIEYVQLGKKRNAELIAELNAEEGEESGKIKRLSPRDIQIQDFKHSLHLLEQVKENIEEGQVFYEDLKESIGVLHEDVTDFLNKS
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.  May act as a scaffold protein that recruits the calpain-like protease RIM13 via VPS32 to its substrate RIM101 (By similarity).
What are the official names of this protein?
pH-response regulator protein palA/RIM20.
What is the protein family that this protein belongs to?
Belongs to the palA/RIM20 family.
Protein: MY14_EISFE
Sequence: GFKDGAADRISHGF
What is the function of this protein?
Has a stimulative effect on the contraction of gut muscles.
What are the official names of this protein?
Myoactive tetradecapeptide, ETP.
What is the protein family that this protein belongs to?
To insects allatotropin.
Protein: LPXK_SHEAM
Sequence: MQSFVHKIWYQGHPAAWLLLPLSLLFWLVSSLRRAAFRLGLKRSERLPVPVVVVGNITAGGSGKTPTVLYLIELLRREGWRPGVISRGYGASFDGELDVVAGMSPAQVGDEPAMIAMRTGIPMVVGRNRIKAAHKLLQCHDVNVILCDDGLQHYALERDVEILVIDGERRFGNGWLLPAGPLREGAWRKNSVNFVLCNGASAEADEYAMTLEPTGLVAVAAIHGKSQAKDNSHNAQDNATPRPGDTVNAMAGIGNPQRFFSTLMAQGFVLEKAHEFADHMAFSETDIATIDDGRPLLMTEKDAVKCREFAKQHWWYLAVDANLPPTFSTRLLDALNRAATAKQGNTHGL
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: YNHA_RHOER
Sequence: HAFHIWNVIATDGGAYQMLDGNGYGMNAEGLYDPELMAHFASRRIQHADALSETVKLVALTGHHGITTLGGASYGKARNLVPLARAAYDTALRQFDVLVMPTLPYVASELPAKDVDRATFITKALGMIANTAPFDVTGHPSLSVPAGLVNGVPVGMMITGRHFDDATVLRVGRAFEKLRGAFPTPAERASNSAPQLSPA
What are the official names of this protein?
Uncharacterized protein in nthA 5'region.
Protein: ENV_FENV1
Sequence: MKPPAGMVFLWVLTSLGAGIGAKIVKEGNPHQVYTLTWQIYSQSGEVVWEVQGNHALNTWWPALTPDFCQLAAGLDTWDIPDRSPKNLETSMEGTSQQLTPQGCSKPWKRCALTERDFYVCPRDNRDRATAHRCGGYEEYFCSAWGCETTGDAYWQPTSTWDLITITRNYTKPDSCDDRVERERKTSRHWRDPLSLPLKITFTDSGKRALGWQTGYTWGLRWYLPGKDRGIILKIKLKIDTITQTVGPNLVLADQKTPVQLAIPVQPPRAPTQTPRVNPVNSTLSPSLGYPAPAPGPRPPYPTSPSRPGTGDRLLNLVQGVYLTLNLTAPNQTQDCWLCLTAKPPYYQGVAIIGNFTNHTNAPLRCSTTPRHGLTLTEVTGYGLCIGKIPPSHQNLCSQTVPSVGQGPYYLTAPNGTYWVCNTGLTPCISLQILNDTADYCILIELWPKIFYHDSEYIYGHYEPGGRFRRDPVSLTVALLLGGLTMGSLAAGIGTGTAALIETNQFKQLQIAMHSDIQALEESISALERSLISLSEVVLQNRRGLDLLFLQEGGLCAALKEECCFYADHTGIVRDSMAKLRERFKQRQKLFESQQGWFEGWYNKSPWFTTLVSSLMVPLILLLLILMFGPCILNHLLQFIRERLSVIQALVLTQQYHQLRQFDAERPDAIE
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.