PharMolix/UniProtQA huggingface dataset:
Protein: CYB_PHYXA
Sequence: MTIMRKNHPLLKLVNDSFIDLPTPSNISSWWNFGSLLGVCLVMQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICMFIHVGRGIYYGSYMLSETWNIGIILLLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPSGLNSNSDKIPFHPYYTIKDLLGVLLLLMVLMILVLFFPDVLGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVMALILSILILALFPLINSSKQHGLVYRPITQFIYWIFIANLLILTWVGGQPVEYPFTMIGQVASIMYFSIIIIFMPIASMIENDILKLHY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ISPE_MYCTU
Sequence: MSASDGNTAELWVPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSAPTEV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: NUOH_NEIG1
Sequence: MQEWFQNLFAATLGLGDLGITVGLVVSVIVKIVIILIPLILTVAYLTYFERKVIGFMQLRVGPNVTGPRGLIQPFADVFKLLFKEVTRPKLSNKALFYIGPIMSLAPSFAAWAVIPFNEEWVLTNINIGLLYILMITSLSVYGVIIAGWASNSKYSFLGAMRASAQSISYEIAMSAALVCVVMVSGSMNFSDIVAAQAKGIAGGSVFSWNWLPLFPIFIVYLISAVAETNRAPFDVAEGESEIVAGHHVEYSGFAFALFFLAEYIFMILIAALTSLMFLGGWLSPFPQSWGIVGTPSAFWMFVKMAAVLYWYLWIRATFPRYRYDQIMRLGWKVLIPIGFAYIVVLGVWMISPLNLWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PK1R_DROME
Sequence: MSAGNMSHDLGPPRDPLAIVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGVPQEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIRIIVLVWIMAIVTAIPQAAQFGIEHYSGVEQCGIVRVIVKHSFQLSTFIFFLAPMSIILVLYLLIGVHLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTAGLMGGSGAQLSSVRGRLNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQHEFVYTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAFKAVLFGKKVSKGSLNSRNNIESRRLRRALTNSSQTQRFSIESAEQPKPSIMQNPTNKPPVAAQYAMIGVQVN
What is the function of this protein?
Receptor for the neuropeptide CAP-3/pyrokinin-1 (TGPSASSGLWFGPRL-amide) (PubMed:16054112).  Also activated weakly by other neuropeptides terminating in the sequence PRL-amide including pyrokinin-2, Hug-gamma, and ecdysis-triggering-hormone-1 (PubMed:12177421, PubMed:16054112).  The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system (PubMed:16054112).
What are the official names of this protein?
Pyrokinin-1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNPA_XYLFA
Sequence: MNSCKRFPRSARICLRSEYYVAFEQGRRYSSVLLRLHHLPTSGPVRLGLVVSRRVDIRAVNRNRIKRALREVMRQIAYKLVPGDYVVVVRQTAKDVSNAELSVALLSLLRRIGALPLAPIDNAMLPFFERNCSRK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: SRS12_HUMAN
Sequence: MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNSW
What is the function of this protein?
Splicing factor that seems to antagonize SR proteins in pre-mRNA splicing regulation.
What are the official names of this protein?
Serine/arginine-rich splicing factor 12, 35 kDa SR repressor protein, SRrp35, Splicing factor, arginine/serine-rich 13B, Splicing factor, arginine/serine-rich 19.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYSP_TRYBB
Sequence: MPRTEMVRFVRLPVVLLAMAACLASVALGSLHVEESLEMRFAAFKKKYGKVYKDAKEEAFRFRAFEENMEQAKIQAAANPYATFGVTPFSDMTREEFRARYRNGASYFAAAQKRLRKTVNVTTGRAPAAVDWREKGAVTPVKVQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTIDSGCNGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDLPQDEDAIAAYLAENGPLAIAVDAESFMDYNGGILTSCTSKQLDHGVLLVGYNDNSNPPYWIIKNSWSNMWGEDGYIRIEKGTNQCLMNQAVSSAVVGGPTPPPPPPPPPSATFTQDFCEGKGCTKGCSHATFPTGECVQTTGVGSVIATCGASNLTQIIYPLSRSCSGPSVPITVPLDKCIPILIGSVEYHCSTNPPTKAARLVPHQ
What is the function of this protein?
The cysteine proteinases have a potential role in host-parasite interaction and virulence.
What are the official names of this protein?
Cysteine proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: PSBB_PANGI
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSVTGGAIPNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFSDERTGKPSLDLPKIFGIHLFLAGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQSVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSAGLAENQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPIFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTRRQVV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LEPA_BUCAT
Sequence: MLKCIKHEYGIKNMKSIRNFSIIAHIDHGKSTLSDRLIQLCGGLSEREMSNQVLDSMDLEKERGITIKAQSVMIDYKNKSGNIFNLNFIDTPGHVDFSYEVSRSLAACEGALLVVDSTQGVEAQTLANCYTAIDMNVEIVPVLNKIDLPNSNADKVAKEIEDIIGIPALDAIRCSAKTGEGIEDLIERIINDIPYPKGSINSPLQALIIDSWFDNYLGVVSLIRIKNGILFEKDKIQVMSTGKNYYVDQIGVFTPKKLNKNQLRCGEVGWIICGIKNIIAAPVGDTLTTAKNPAKNMIIGFKKIKPQIYAGLFPLTSDQYEMFRDALGKLSLNDASLFYEPENSVALGFGFRCGFLGVLHMEIIQARLEREYSIDLITTIPTVIYEIELINGKIIYLDTPSNFPNMNDIKIIKEPIVECSILSPPQFLGSIIKLCIKKRGVQINMVYHSHQVLLKYNIPMNEVILNFFDELKSVSSGYASLEYDFKYFQSVKMVRIDILINSEKVDALTILSYHKNAQSRSREIVDKMKKLIPRHQFDISIQAVINNSVIARSTIKQLRKNVLSKCYGGDVSRKKKLLQKQKDGKKRMKKIGNVNVPKTVFLSILNSRES
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HEMA_CVMJH
Sequence: MGSTCIAMAPRTLLLLIGCQLVFGFNEPLNIVSHLNDDWFLFGDSRSDCTYVENNGHPKLDWLDLDPKLCNSGKISAKSGNSLFRSFHFTDFYNYTGEGDQIVFYEGVNFSPNHGFKCLAYGDNKRWMGNKARFYARVYEKMAQYRSLSFVNVPYAYGGKAKPTSICKHKTLTLNNPTFISKESNYVDYYYESEANFTLAGCDEFIVPLCVFNGHSKGSSSDPANKYYMDSQSYYNMDTGVLYGFNSTLDVGNTAKDPGLDLTCRYLALTPGNYKAVSLEYLLSLPSKAICLRKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGGTHDVHHGDFHFRQLLSGLLLNVSCIAQQGAFLYNNVSSSWPAYGYGQCPTAANIGYMAPVCIYDPLPVVLLGVLLGIAVLIIVFLILYFMTDSGVRLHEA
What is the function of this protein?
Structural protein that makes short spikes at the surface of the virus.  Contains receptor binding and receptor-destroying activities.  Mediates de-O-acetylation of N-acetyl-4-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells.  This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell.  May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one.  May become a target for both the humoral and the cellular branches of the immune system.
What are the official names of this protein?
Hemagglutinin-esterase, HE protein, E3 glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the influenza type C/coronaviruses hemagglutinin-esterase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In infected cells becomes incorporated into the envelope of virions during virus assembly at the endoplasmic reticulum and cis Golgi. However, some may escape incorporation into virions and subsequently migrate to the cell surface.
Protein: PNCB_CHRVO
Sequence: MPKNTPIIRSLLDTDLYKFTMLQVVLHQFPAAHGEYEFRCRNHPDTPLTQLKQQLETQLDLLCELRFSQDELDYLRGLRFIKSDYVDYLELFHLQRRFISVSEEGEQLAIRIKGPMVQAMFFEIFVLAIVNELYFRPLDSKAVREEGRRRLEAKLAELERFQREEAPGQRFPLLIADFGTRRRFSRDWQAHVVERLNHALPQVFRGTSNVYLARKLGITPIGTMAHEFFQAFQALGVRLRDFQKAALESWVQEYRGDLGIALTDVVGMDAFLADFDLYFAKLFDGLRHDSGDPYIWGEKAIAHYRKLRIDPATKMLTFSDGLSVDSALQLQRHFSPHIQVSFGIGTHFTNDMGLEPLQIVLKLVSCNGQPVAKLSDSPGKTMCSDETFLAYLRQVFKVPALA
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: RRP42_METKA
Sequence: MDLDLLARIKRHEVLAAIRAGERIDGRDFEEFRPIEVRAGVISKANGSALVRLGNTQLVVGVKLEVGRPYPDSPNEGALAVNAELVPLADPSFEPGPPDENAIELSRVVDRGIRESEMIDLEELCIEEGEHCWVTFVDIHVLDHDGNLFDASMIGSVSALSITEVPKAEVVDDEVEVMEEDTEPLAINDFPISVTIAKVGEYLLVDPCLEEEVIMDTRLTVTVTESGEVCAVQKGELGDFPEHLLEDAIDLATKKAEEVRRTVKAQL
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Contributes to the structuring of the Rrp41 active site.
What are the official names of this protein?
Exosome complex component Rrp42.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp42 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_STEPS
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKMK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MTP2_ORYSJ
Sequence: MGFRLAHLAACVARAAASSSRLRGPRPAASALVAPLLASPWEPSGGGQPHWLVPSRGHVGHSHHHHHGEEVGGEASERIFRLGLAADVVLTVGKAVTGYLSGSTAIAADAAHSLSDIVLSGVALLSYKAAKAPRDKEHPYGHGKFESLGALGISSMLLVTAGGIAWHAFDVLQGVMSSAPDIIGNVSHAHHSHGSSGHHHGIDLEHPILALSVTAFAISVKEGLYWITKRAGEKEGSGLMKANAWHHRSDAISSVVALLGVGGSILGVPYLDPLAGLVVSGMILKAGVHTGYESVLELVDAAVDPSLLQPIKETILQVDGVKGCHRLRGRKAGTSLYLDVHIEVYPFLSVSAAHDIGETVRHQIQKSHNQVAEVFIHIGSLQPLNQNAL
What is the function of this protein?
Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis.
What are the official names of this protein?
Metal tolerance protein 2, OsMTP2.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: 3L25_NAJNA
Sequence: IRCFITPDITSKDCPNGHVCYTKTWCDGFCSRRGERVDLGCAATCPTVKTGVDIQCCSTDDCDPFPTRKRP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 5, Toxin E.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: S130B_ARATH
Sequence: MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII
What is the function of this protein?
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA.  Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.  May also be involved in the assembly of the 'E' complex.  Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (By similarity).  Required for pollen and ovule development, especially during the transition from microspore to the bicellular stage in pollen development.  Involved in the accumulation of QRT1 and QRT3 (PubMed:21680607).
What are the official names of this protein?
Spliceosome-associated protein 130 B, AtSAP130b, SAP 130 B, Pre-mRNA-splicing factor SF3b 130 kDa subunit B, SF3b130 B.
What is the protein family that this protein belongs to?
Belongs to the RSE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YJ151_YEAST
Sequence: MLSLIFYLRFPSYIRG
What are the official names of this protein?
Uncharacterized protein YJR151W-A.
Protein: GATC_ARTS2
Sequence: MAAINRDDVAHLARLAHIEMSAEELDRMAGELAVIVESVKSVSEAAGDDVPATSHPIPLTNVFREDVVGHTFTAEQSLSGAPDAYEGRFKVPAILDED
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: COBQ_XANCB
Sequence: MSARVLMVQGCTSDAGKSTLVAALCRWLHRQGVAVAPFKPQNMALNSAVTVDGGEIGRAQAVQAQACGLPPHTDFNPVLLKPNSDTGAQVIVHGHPVATLDAVGYHAYKRTARTAVLASHARLVERFDVLLVEGAGSPAEINLREHDIANMGYAEAVDCAVILIADINRGGVFAHLVGTLALLSPSERARVAGFVINRFRGDLALLQPGLEWLERETGKPVLGVLPYLHGLQLDAEDALPRGPVHKPQARLRVVVPVLPRISNHTDLDALLAHPQVDVQLIGPGQSVPPCDLIVLPGSKSTRQDLAWLRAQGWEAAIARHLRYGGKLLGICGGLQMLGEQVHDPHGIEGAPGSSAGLGWLALQTALQPHKQLHRVGGRLLPSGAAVSGYEIHCGLSTGAALARPLLQLDDGRSDGAVSEDGQVMGTYLHGIFDHPAALAALLAWAGLADAAPLDLASLREATLERLADTVHAHLDIAALTRLTLGEPACAN
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: OBG_POLNA
Sequence: MKFVDEAYIDIAAGDGGSGCVSFSHEKYKEFGGPNGGDGGRGGHVYAVADINLNTLVDFRFSRRHEARNGGHGMGSDMFGAKGDDIILKMPVGTILTDAETGEVLFELLVPGEQILIAKGGDGGFGNLRFKSSTNRAPRSKTPGWPGDRKSLKLELKVLADVGLLGMPNAGKSTFISAVSNARPRIADYPFTTLHPNLGVVRVGPEQSFVVADLPGLIEGASEGAGLGHLFLRHLQRTRLLLHIVDLAPFDEGVDPVAQAKAIVGELKKYDEALYKKPRWLVLNKLDMIDADERAAVVKDFVKRFKFKGPVFEISALTREGCEQLVKTIYQHVKKVQKSEQPEEEVDPRFIELPPEPAKPASSD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_NOSS1
Sequence: MTEKQTWSQRFESALHPAIALFNASISFDIELIEYDLTGSQAHAQMLAHTGIISPAEGEQLVAGLEQIREEYRQGKFQPGIDAEDVHFAVERRLTEIVGDVGKKLHTARSRNDQVGTDTRLYLRDQILQIKTQLREFQRVLLDIAEKNVETLIPGYTHLQRAQPVSLAHHLLAYFQMAQRDWERLGDVYRRVNISPLGCGALAGTTFPIDRHYTAELLQFERIYENSLDGVSDRDFAIEFLCAASLIMVHLSRLSEEIILWASEEFRFVILKDSCATGSSIMPQKKNPDVPELVRGKTGRVFGHLQAMLVIMKGLPLAYNKDLQEDKEGLFDSVNTVKACLEAMTILLQEGLEFRTQRLAEAVTQDFSNATDVADYLAARGVPFREAYNIVGKVVKTSIAAGKLLKDLTLEEWQQIHPKFADDIYEAISPRQVVAARNSYGGTGFAQVSKAVSAARKEIGE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_LEPBJ
Sequence: MSQDLEQKLWSIASGIPFVSDYFLQASPARKLKKENLFSKVFETYFLELGSGWGEVAIAMALQRRNTGFVLMEKKFDRIRHTIREIEKHSLDNVKILCVNFNWFLADVFEENLFSEILLNFPDPWPKKRHHKKRTINSKFIESLRVLLPEKGKFSFATDYGPYARKTIRLFRDSEIFKPETMEFRLERKEIPVSHFERKKRKEGKRIYYIDQILIRK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: NANOG_HUMAN
Sequence: MSVDPACPQSLPCFEASDCKESSPMPVICGPEENYPSLQMSSAEMPHTETVSPLPSSMDLLIQDSPDSSTSPKGKQPTSAEKSVAKKEDKVPVKKQKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRWQKNNWPKNSNGVTQKASAPTYPSLYSSYHQGCLVNPTGNLPMWSNQTWNNSTWSNQTQNIQSWSNHSWNTQTWCTQSWNNQAWNSPFYNCGEESLQSCMQFQPNSPASDLEAALEAAGEGLNVIQQTTRYFSTPQTMDLFLNYSMNMQPEDV
What is the function of this protein?
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal.  Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages.  Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes.  Acts as a transcriptional activator or repressor.  Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'.  Binds to the POU5F1/OCT4 promoter (PubMed:25825768).  Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression.  When overexpressed, promotes cells to enter into S phase and proliferation.
What are the official names of this protein?
Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog.
What is the protein family that this protein belongs to?
Belongs to the Nanog homeobox family.
Protein: GCS22_FRAAA
Sequence: MTTEGVRTVGVEEEFVLVDPDRHAVRAAASRVLARGDRDGAGGPPGGADPDGDLDGDLDVELTREQVESGSAPHTSLAGLRGSLVGLRRAAARAAEAAGVALAATATCPTPTRPTITPKPRYERMRGEFGLTAREQLTCGCHVHVAVHSRQEAVGALDRLRPWLSVLVAMTANSPFWQGADSGYASYRTQVWQRWPTAGATGAFGSPAEYDRVVDLLIRTGAAMDDGMIYFDVRLSHHYPTLELRVADVCLSVDDSVLLAALARALVATAARQWAAGEPVPTVRPELLRAAGWRASRHGVSGELVDLERGELVPARALVDRFVEWVGPELSATGDGDAVAALVDNLFARGTGADRQRAAYARRGRIDDVVDLVIRETTTMASP
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-2, Gamma-glutamylcysteine synthetase 2-2, GCS 2-2, Gamma-GCS 2-2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.