PharMolix/UniProtQA huggingface dataset:
Protein: RAD21_BOVIN
Sequence: MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDDDMLASTGASNLLLEPEQSTSNLNEKINHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGGIFDDPPALSEAGVMLPEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPILEEPSRLQESMETSRTNLDESAMPPPPPQGVKRKAGQIDPEPMIPPQQAEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRFHII
What is the function of this protein?
May promote apoptosis.
What are the official names of this protein?
Double-strand-break repair protein rad21 homolog.
What is the protein family that this protein belongs to?
Belongs to the rad21 family.
What are the subcellular locations of this protein?
[Double-strand-break repair protein rad21 homolog]: Nucleus. Nucleus matrix. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Note=Associates with chromatin. Before prophase, scattered along chromosome arms. During prophase and prometaphase, most cohesins dissociate from the arms of condensing chromosome, possibly through PLK1-mediated phosphorylation (By similarity). A small amount of cohesin remains in centromeric regions and is removed from chromosomes only at the onset of anaphase. At anaphase, cleavage by separase/ESPL1 leads to the dissociation of cohesin from chromosomes and chromosome separation (By similarity). SUBCELLULAR LOCATION: [64-kDa C-terminal product]: Cytoplasm, cytosol. Nucleus.
Protein: ODPB_STAAS
Sequence: MAQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGIGGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFGGGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLISSIRSNDPVVYLEHMKLYRSFREEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQPIDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAELSERAILSLEAPIGRVAAADTIYPFTQAENVWLPNKNDIIEKAKETLEF
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.
Protein: LPXH_SALHS
Sequence: MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DDL_MYCTA
Sequence: MSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARGVGLH
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_NEIMB
Sequence: MHKIPKGTALAFDFGEARIGVAQGDAELGLSHPLSTVTGGSNDEKFAAIAKLVQEWQPRYFVVGLPVHTDGTKHEMTHLSRKFGRRLNGRFNLPVYWVDERLSSVYAESLLSEAQVFGKKRKSVLDQVAAQAILHGFFEGGPAECFNGREG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THNS1_HUMAN
Sequence: MLHFNRCHHLKKITQKCFSSIHVKTDKHAQRFLSRTFALAELRKSWYSTHSLVGDKNIILMGPPGAGKTTVGRIIGQKLGCCVIDVDDDILEKTWNMSVSEKLQDVGNEQFLEEEGKAVLNFSASGSVISLTGSNPMHDASMWHLKKNGIIVYLDVPLLDLICRLKLMKTDRIVGQNSGTSMKDLLKFRRQYYKKWYDARVFCESGASPEEVADKVLNAIKRYQDVDSETFISTRHVWPEDCEQKVSAKFFSEAVIEGLASDGGLFVPAKEFPKLSCGEWKSLVGATYVERAQILLERCIHPADIPAARLGEMIETAYGENFACSKIAPVRHLSGNQFILELFHGPTGSFKDLSLQLMPHIFAHCIPPSCNYMILVATSGDTGSAVLNGFSRLNKNDKQRIAVVAFFPENGVSDFQKAQIIGSQRENGWAVGVESDFDFCQTAIKRIFNDSDFTGFLTVEYGTILSSANSINWGRLLPQVVYHASAYLDLVSQGFISFGSPVDVCIPTGNFGNILAAVYAKMMGIPIRKFICASNQNHVLTDFIKTGHYDLRERKLAQTFSPSIDILKSSNLERHLHLMANKDGQLMTELFNRLESQHHFQIEKALVEKLQQDFVADWCSEGECLAAINSTYNTSGYILDPHTAVAKVVADRVQDKTCPVIISSTAHYSKFAPAIMQALKIKEINETSSSQLYLLGSYNALPPLHEALLERTKQQEKMEYQVCAADMNVLKSHVEQLVQNQFI
What are the official names of this protein?
Threonine synthase-like 1, TSH1.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: MUTL_HALSA
Sequence: MTDRIRALDDATVARIAAGEVVERPASVVKELVENSLDAGAASVDVSVDAGGTDRIVVADDGRGMTGDDLRMAVRQHTTSKLDDASGLDGVGTLGFRGEALYTIGSVAELTVTTRPRNAGDTGARITVDHGDAGSVAPAGHPAGTTVEVTDLFGETPARRKYLKRAATEFGHVNRAVTRYALANPDVAVSLTHDGREVFATTGTGDVQDAALAVYGREVAQSLRTVDADPAADSVERVHGYVSDPEVTRSTREYLATFVNGRAVTDAVLREAVLDGYGDQLAPDRYPFAVLFVDCEGVDANVHPRKLEVRFEDEAGVKAAVEAGVRDALLDAGLVRAGAPRGASKPGDAEISPEHSPTDRDAGAAGGGDAAGQSDGNGQRTAASGATSESPASAFETGGGDEAADSAASTDGTRERPGSGTESRTGRFDAPAENARLPTGAGGPEADDQDTTSERDSLPDLRVLGQLHDTYVVAEAGDGLVLVDQHAADERVHYERLQARVDGASQALVAPAELELTAGEAAVFEAALGGLRELGFDAELAGRTARVTAVPAVLADALDAELARDVLSSFLADADGTPVADAADAVLADLACSPAIKGNTSLAEGSVVALLDALDACENPYACPHGRPTIVEVDGDELAARFERDYPGHAGRRREDAGN
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: IF2_SHEFN
Sequence: MADTSVEKLAAEVGKSVDRLIEQFSQAGMNKKQLDTVSEKEKQQLLDYLKKQHGADSVPTKMTLQRKTVSTLSVASTGGQSKDVKVEVRKKRTFVKRDDAELAKQAELETQAKAKAEAEAQAKVEAEAKAAAEAKATADAKKKAEAEAKLKSEKVKSEPKVTKVADPETAAAKVEADRLKATQEAVLTQKQKDEAAKAAETARQLAEVNSKRWAEEERQRLDAEKNGDHHITTSKVARAAEDSSDADDEKRGRRARNKNANKKRGGKDARDGREKHMRNRSTAPESMAHGFNKPAAAVSRDVRIGETVTVSELAHLMAIKATVIIKQMMKMGTMVTINQVLDQETAQMVAEELGHKVVLIRENELEHQVLKDRDDNIQLESRAPVVTIMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAKATDIVILVVAADDGVMPQTIEAIQHAKAGNVPLIVAVNKMDKPDADPERVKSELSQHGIMSDDWGGDNMFVHVSAKTGMGVDELLEGILLQSEVLELKAVRDGMAAGVVIESQLDKGRGPVATILVQEGTLRQGDIVLCGLEYGKIRAMKDENGHAITEAGPSIPVEILGLSGVPSAGDEATVVRDERKAREVALYRQGKFRDVKLARQQKSKLENMFANMEEGEVQELNIVLKADVQGSLEAICESLAKLSTDEVKVNIIARGVGALTETDATLAAASNAILVGFNVRADAQARKTIDSESVDLRYYSIIYNLIDEVRAAMTGMLAPEFRQEIIGLAEVRDVFKSPKIGAIAGCMVTEGIVKRSAPIRVLRDNVVIFEGELESLRRFKDDAPEVRNGMECGIGVKNYNDVRVGDQIEVFETVEIARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_ECOUT
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTDDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENDLGVGYYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGA17_ARATH
Sequence: MAMTSWPSTGRQRRHQLASMLLLVLVVVGIYVPVFALLPSLSYTPQSLPSAIPQDEKMISRKFYIKDDNFWKDGNRFQIIGGDLHYFRVLPEYWEDRLLRANALGLNTIQVYVPWNLHEPKPGKMVFEGIGDLVSFLKLCEKLDFLVMLRAGPYICGEWDLGGFPAWLLAVKPRLQLRTSDPVYLKLVERWWDVLLPKVFPLLYSNGGPVIMVQIENEYGSYGNDKAYLRKLVSMARGHLGDDIIVYTTDGGTKETLDKGTVPVADVYSAVDFSTGDDPWPIFKLQKKFNAPGRSPPLSSEFYTGWLTHWGEKITKTDAEFTAASLEKILSRNGSAVLYMVHGGTNFGFYNGANTGSEESDYKPDLTSYDYDAPIKESGDIDNPKFQALQRVIKKYNASPHPISPSNKQRKAYGSIKMQMTTSLFDLVRMTDPADVITSANPISMESVGQMFGFLLYESSYIAKKSGNTLRIPKVHDRAQVFVSCLSQDVDVGVLRYIGTTERWNNQPISLPTIECTTNTSLFILVENMGRVNYGPYIFDDKGILSSVYLDGQILHGWKMIPIPFHNLNQEPNLTFEMQHTKNRSKKFELTNDVGRKEPALFAGEFSINSEEEIKDTYLSFNGWGKGVAFVNEFNIGRYWPSVGPQCNLYVPAPLLKRGKNTLVVFELESPHLELSLEAVDHQDFTCGSNVSKVNQL
What are the official names of this protein?
Beta-galactosidase 17, Lactase 17.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: MNTH_RHILO
Sequence: MSDAEATAPRSSWRFAGRDEDDQPSLREVNSTIAVPSSGVWFRRLFAFMGPGYMVSVGYMDPGNWATDLAGGAQFGYTLLFVIMLSNLMAILLQALAARLGIATGRDLAQACRAYYPRPVNFVLWIACELAIIACDLAEVIGTAIALKLLFGIPLIGGAILTALDAFLVLLLMNKGFRYLEAFVIALLIIIFSCFAIQIFVAAPPAGTILHSMFVPSSEIVTNPAMLYIAIGIIGATVMPHNLYLHSSIVQTRAYERTEKGKRDAIKWATTDSTIALMLALFVNAAILIVSAVAFHNTGHQDVAEIDQAFELLSPLLGLGIASILFAVALLASGLNSTVTATLAGQIIMEGFLRLRIPNWARRLLTRGLAIVPVVVVTALYGEKGTGQLLVFSQVILSMQLPFAVVPLVQFVSDKKKMGNLAIPRGVAALAWVVAAIILVLNFKLLYDTLFGVG
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EX7L_BACAA
Sequence: MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDFTIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQAKEFAFVRAAQKLEALSPLKVMMRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOM3_STRWE
Sequence: MTIGSLGSTEFALHGKPAIRWGDLPQRVGKPETRRYQKVLLLNPSATLFRHDLPRCTYPLGLGYIAAVLEKYGYEVKILDVFAEGYYNAQPVDGDDQFLRYGLSDDDIVKVMKEFGPDVVGISSIFSNQADNVHHLLKLADLVTPEAVTAIGGAHARYFPKACLDDPNLDAVFLGEGEMTFLLWMEHLNGNVSDDEVHGIAWRDRDGKVQIKPELPLISSMRPEGPETGKSSPMLSMAGELDHIPFPAWHHYNMEKYFEIKAYQSPYTVGSRVGQLYTSRGCTAHCTFCTTTHFWGQKLRRRSVQDVVDEVLRLRDEYGIDEFHIQDDNITNDMDHARELFRAFKEVGLPWATPQGTALWRMDEELLDLMAESGAYQVTFAIESGVQRVLKELIKKPLNLERTSHLIKYARSLGMHVHGFFIIGMPPMCGNAGESIEEMQASYDYAEEAGFSSASFFAASPIVGSELLRECIRQGFVDPEESLYRMTYKQGIINVPGLWDGEEIAELAAKFNRDFNARRDRAYTPQKQWNANQY
What is the function of this protein?
Involved in fosfomycin biosynthesis (PubMed:17220970, PubMed:24370735, PubMed:28678474).  Catalyzes the C-methylation of cytidylyl-2-hydroxyethylphosphonate (HEP-CMP) to form cytidylyl-2-hydroxypropylphosphonate (HPP-CMP).  The C-methylation is not stereoselective and the ratio of (S)- to (R)-HPP-CMP is almost equal in vitro (PubMed:28678474).
What are the official names of this protein?
Cytidylyl-2-hydroxyethylphosphonate methyltransferase, MeCbl-dependent radical SAM C-methyltransferase Fom3.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily.
Protein: SNP33_ARATH
Sequence: MFGLRKSPANLPKHNSVDLKSSKPNPFDSDDESDNKHTLNPSKRTTSEPSLADMTNPFGGERVQKGDSSSSKQSLFSNSKYQYKNNFRDSGGIENQSVQELEGYAVYKAEETTKSVQGCLKVAEDIRSDATRTLVMLHDQGEQITRTHHKAVEIDHDLSRGEKLLGSLGGMFSKTWKPKKTRPINGPVVTRDDSPTRRVNHLEKREKLGLNSAPRGQSRTREPLPESADAYQRVEMEKAKQDDGLSDLSDILGELKNMAVDMGSEIEKQNKGLDHLHDDVDELNFRVQQSNQRGRRLLGK
What is the function of this protein?
t-SNARE involved in diverse vesicle trafficking and membrane fusion processes, including cell plate formation.  May function in the secretory pathway.
What are the official names of this protein?
SNAP25 homologous protein SNAP33, AtSNAP33, Snap25a, Synaptosomal-associated protein SNAP25-like 1, SNAP-25-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Membrane. Note=Plasma membrane, some endomembrane compartment and cell plate in dividing cells.
Protein: GREB_HAEDU
Sequence: MAKSNYITRAGWQALDQELKYLWKEERPKVTQSVSEAAALGDRSENAEYIYGKRRLREIDRRIRFLSKRLEALQIIDYHPQQAGKVFFGAWIELENNEGEINQYRIVGCDEFDPTKNWISIDSPVARALIGKCVDDEIEVQTPTGKAVFYINKIWYDTKSLY
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreB releases sequences of up to 9 nucleotides in length.
What are the official names of this protein?
Transcription elongation factor GreB, Transcript cleavage factor GreB.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family. GreB subfamily.
Protein: Y1604_STAAW
Sequence: MKIKEMVTSEMPRERLLSHGAKSLSNTELLAILINTGRKGFSSIDISNELLKSASNLNELKKSSINDLIKVKGIGLQKAITLKAAFELGERMGRRAENNRIKITQPSDVADYMIPTMKDLTQEHFVILLLNSKNVVIKETCVFKGTLNSSIVHPREIFSIAVRENANAIIAVHNHPSGDVTPSQEDIITTMRLKECGLILGIDLLDHIIIGDNRFTSLVEAGYFDEND
What are the official names of this protein?
UPF0758 protein MW1604.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: PNP_BACHK
Sequence: MSQEKQVFSIDLAGRQLTVETGQLAKQANGAVLVRYGDTAVLSTATASKEAKNVDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAILASRLIDRPIRPLFADGFRNEVQVVSIVMSVDQDCSSEMAAMLGSSLALSISDIPFEGPIAGATVGRINGEFVINPTVEQQEQSDIHLVVAGTKDAINMVEAGADQVPEETMLEAIMFGHDEIKRLIAFQEEIVQAVGKEKSEVKLYEVDADLNQAVREMAEKDMHSAIQVHEKHAREDAINEVKKRVIEHYEAQEADADTLGQVNEILYKIVKEEVRRLITVEKIRPDGRKGDEIRPLASEVGILSRTHGSGLFTRGQTQALSICTLGALGDVQILDGLGVEESKRFMHHYNFPSFSVGETRPMRGPGRREIGHGALGERALEPVIPSEKDFPYTVRLVSEVLESNGSTSQASICGSTLAMMDAGVPLKAPVAGIAMGLVKTGEHYTILSDIQGMEDHLGDMDFKVAGTAHGVTALQMDIKIDGLSREILEEALQQAKVGRVHILNHMLSVIAEPRTELSAYAPKIITMTINPDKIRDVIGPSGKQINKIIEETGVKIDIEQDGTVFISSINQEMNDKAKKIIEDIVREVQVGEIYEGKVKRVEKFGAFVELFSGKDGLVHISELALERVGKVEDVVKIGDVITVKVIEIDKQGRVNLSRKVLLKEEQEKEAAKEENKQEQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_MYCTO
Sequence: MSGMILDELSWRGLIAQSTDLDTLAAEAQRGPMTVYAGFDPTAPSLHAGHLVPLLTLRRFQRAGHRPIVLAGGATGMIGDPRDVGERSLNEADTVAEWTERIRGQLERFVDFDDSPMGAIVENNLEWTGSLSAIEFLRDIGKHFSVNVMLARDTIRRRLAGEGISYTEFSYLLLQANDYVELHRRHGCTLQIGGADQWGNIIAGVRLVRQKLGATVHALTVPLVTAADGTKFGKSTGGGSLWLDPQMTSPYAWYQYFVNTADADVIRYLRWFTFLSADELAELEQATAQRPQQRAAQRRLASELTVLVHGEAATAAVEHASRALFGRGELARLDEATLAAALRETTVAELKPGSPDGIVDLLVASGLSASKGAARRTIHEGGVSVNNIRVDNEEWVPQSSDFLHGRWLVLRRGKRSIAGVERIG
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_IBVBC
Sequence: MASGKAAGKTDAPAPVIKLGGPKPPKVGSSGNASWFQAIKAKKLNTPPPKFEGSGVPDNENIKPSQQHGYWRRQARFKPGKGGRKPVPDAWYFYYTGTGPAADLNWGDTQDGIVWVAAKGADTKSRSNQGTRDPDKFDQYPLRFSDGGPDGNFRWDFIPLNRGRSGRSTAASSAAASRAPSREGSRGRRSDSGDDLIARAAKIIQDQQKKGSRITKAKADEMAHRRYCKRTIPPNYRVDQVFGPRTKGKEGNFGDDKMNEEGIKDGRVTAMLNLVPSSHACLFGSRVTPKLQLDGLHLRFEFTTVVPCDDPQFDNYVKICDQCVDGVGTRPKDDEPKPKSRSSSRPATRGNSPAPRQQRPKKEKKLKKQDDEADKALTSDEERNNAQLEFYDEPKVINWGDAALGENEL
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the gammacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: A18_CWPXB
Sequence: MSLLKMEYNLYAELKKMTCGQPISLFNEDGDFVEVEPGSSFKFLIPKGFYASTSVKTSLVFETLTTTDNKITSINPTNAPKLYPLQRKVVSEVVSNMRKMIELKRPLYITLHLACGFGKTITTCYLMATHGRKTVICVPNKMLIHQWKTQVEAVGLEHKISIDGVSSLLKELKTQSPDVLIVVSRHLTNDAFCKYINKHYDLFILDESHTYNLMNNTAVTRFLAYYPLMMCYFLTATPRPANRIYCNSIINIAKLSDLKKTIYAVDSFFEPYSTDNIRHMVKRLDSPSNKYHIYTEKLLSVDEPRNQLILDTLVEEFKSGTINRILVITKLREHMVLFYKRLLDIFGPEVVFIGDAQNRRTPDMVKSIKDLNRFIFVSTLFYSGTGLDIPSLDSLFICSAVINNMQIEQLLGRVCRETELLDRTVYVFPSTSIKEIKYVIGNFVQRIISLSVDKLGFKQESYRKHQESEPASVPTSSREERVLNRIFNSQNR
What is the function of this protein?
DNA helicase which seems to act as a postreplicative transcription termination factor.  Involved in ATP-dependent release of nascent RNA.  Forms a stable complex with single-stranded DNA, and to a lesser extent RNA (By similarity).
What are the official names of this protein?
Transcript termination protein A18.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Poxviruses subfamily.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: CEC4_CAEEL
Sequence: MAKKTVEGEHGTPKTNFTKKETSKNHDDFKKIIGHKVVEEHYVEYEVELTSGKTITATEFDFKGDDSLLSTYKKKVTKQSDDSSGEYAVERVLAHRKVKGSPLYLVQWKGYPHPVWNSEMWEEDLDNCKDLLAAYKKHQEDLKIAQTPKKTPSKTPKKTPKSLKRRALTPSDDEEEAGPIAPEPKKTPKQSTKKLKRTTSPETNLVEKSKKKAIPDLENHTLDQEKNDVIERVEEIQEDEDDDDEQREEVVTTAPVETKSRWGFGSWKWF
What is the function of this protein?
Chromatin anchor protein which binds to methylated lysine residues on histone H3, thereby recruiting heterochromatin to the nuclear periphery, especially in embryonic cells, with a lesser role in differentiated cells (PubMed:26607792, PubMed:31118512).  May be required for the correct positioning of chromatin and nucleoli in embryos (PubMed:26607792).
What are the official names of this protein?
Chromo domain-containing protein cec-4.
What are the subcellular locations of this protein?
Nucleus inner membrane. Membrane; Peripheral membrane protein.
Protein: RUVC_PSEPF
Sequence: MTLILGIDPGSRITGYGIVRDTGRGGCIYVASGCIRTGAGELHERLQIVYRGVREIIQTYGPVTMGIEKVFMAKNADSALKLGQARGAAIVAGAEESLEIAEYTATQVKQAVVGTGAANKEQVQMMVMHMLKLTSKPQIDASDALAIAICHAHTRSSLLPHGLGTARSRGGRLRL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NU2M_PANPA
Sequence: MNPLAQPIIYSTIFAGTFITVLSSHWFFTWVGLEMNMLAFIPVLTKKMSPRSTEAAIKYFLTQATASMILLMAILSNNMLSGQWTMTNTTNQYSSLMIMTAMAMKLGMAPFHFWVPEVTQGTPLMSGLLLLTWQKLAPISIMYQMSSSLNVNLLLTLSILSIMAGSWGGLNQTQLRKILAYSSITHMGWMMAVLPYNPNMTILNLTIYIILTTTTFLLLNLNSSTTTLLLSRTWNKLTWLTPLIPSTLLSLGGLPPLTGFLPKWVIIEEFTKNNSLIIPTTMAIITLLNLYFYLRLIYSTSITLLPMSNNVKMKWQFEHTKPTPFLPTLITLTTLLLPISPFMLMIL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.