PharMolix/UniProtQA huggingface dataset:
Protein: PDXB_PSEAE
Sequence: MRILADENIPVVDAFFADQGSIRRLPGRAIDRAALAEVDVLLVRSVTEVSRAALAGSPVRFVGTCTIGTDHLDLDYFAEAGIAWSSAPGCNARGVVDYVLGCLLAMAEVRGADLAERTYGVVGAGQVGGRLVEVLRGLGWKVLVCDPPRQAREPDGEFVSLERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQALRRLLEGGADLEVALDVWEGEPQADPELAARCLIATPHIAGYSLEGKLRGTAQIYQAYCAWRGIAERVSLQDVLPETWLAGLQLNPGCDPAWALATLCRAVYDPRSDDAAFRRSLTGDSATRRAAFDALRKHYPPRREITGLRVATGGQAELQRVVRALGAQLV
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_BACMK
Sequence: MIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVIFVAFIVFYMKKYAKTDKLLGISLGLILGGAIGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTVLEGKKAKE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FHIT_MOUSE
Sequence: MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFRDLHPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHVLPRKAGDFPRNDNIYDELQKHDREEEDSPAFWRSEKEMAAEAEALRVYFQA
What is the function of this protein?
Possesses dinucleoside triphosphate hydrolase activity (By similarity).  Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP (By similarity).  Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP (By similarity).  Exhibits adenylylsulfatase activity, hydrolyzing adenosine 5'-phosphosulfate to yield AMP and sulfate (By similarity).  Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (By similarity).  Exhibits adenylylsulfate-ammonia adenylyltransferase, catalyzing the ammonolysis of adenosine 5'-phosphosulfate resulting in the formation of adenosine 5'-phosphoramidate (By similarity).  Also catalyzes the ammonolysis of adenosine 5-phosphorofluoridate and diadenosine triphosphate (By similarity).  Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5 (By similarity).  Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways (By similarity).  Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis (By similarity).  Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity (By similarity).  Functions as tumor suppressor (PubMed:10758156, PubMed:11517343).
What are the official names of this protein?
Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Adenosine 5'-monophosphoramidase FHIT, Adenylylsulfatase, Adenylylsulfate-ammonia adenylyltransferase, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Fragile histidine triad protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: Y2632_MYCTU
Sequence: MTDSEHVGKTCQIDVLIEEHDERTRAKARLSWAGRQMVGVGLARLDPADEPVAQIGDELAIARALSDLANQLFALTSSDIEASTHQPVTGLHH
What are the official names of this protein?
Uncharacterized protein Rv2632c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1738.
Protein: PGMD_ASPTN
Sequence: MAQPELDLSKAPAHWGMNFTETTHQQPSRRIDPSNVTFPQGYTVVVIGAGKGIGEHIAKAYVQARAENIVITSRTGSDLDRVKKELETLAQQTGQAVKVSTLVQDATKPESYTKLKDLLEEGFNGRLDTLVFCAGGGPVGTLWTPHIDETDVDEWNESIALNFTGSYYAAKYLVPLMLRPQSHGKTIVNITSAASHFTGGNITPASYSIGKLALNRFTQILGENYADQGLVVVAVHPGSSPTPGALGSMPPSLHNILTDDQGLCGAVCVWISKEKRDWISGRYICATWDMDDLESKKEEIVKEDKLKWRMAV
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of pleosporalin A, ascomycone A, as well as a third cryptic naphthoquinone derived pigment, all responsible for the coloration of conidia (PubMed:28471414, PubMed:35351612).  Essential for the production of pleosporalin A, but not the 2 other final products (PubMed:35351612).  The pathway begins with the biosynthesis of the cyclized heptaketide 3-acetonyl-1,6,8-trihydroxy-2-naphthaldehyde by the NR-PKS pgmA.  The C-6 hydroxyl group is further methylated by the O-methyltransferase pgmB to yield fusarubinaldehyde which is in turn oxidized by the cytochrome P450 monooxygenase pgmC at C-9.  The C-1 hydroxyl group is then methylated spontaneously.  Although pgmE, pgmD and pgmH are essential for the production of pleosporalin A, it is not the case for the 2 other final products and it remains difficult to assign a specific function to each enzyme.  PgmF and pgmG seem not to be involved in pigment biosynthesis although they were regulated by the cluster-specific transcription factor pgmR (PubMed:35351612) (Probable).
What are the official names of this protein?
Short chain dehydrogenase pgmD, Pigmented naphthoquinones biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ARSR_ECOLI
Sequence: MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAKIIDEAWRCEQEKVQAIVRNLARQNCSGDSKNICS
What is the function of this protein?
Transcriptional repressor for the arsEFG operon.  ArsE is a trans-acting regulatory protein which controls its own expression.  The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)) (By similarity).
What are the official names of this protein?
Arsenical resistance operon repressor.
Protein: MTNA_KOMPG
Sequence: MSLQAIKFDRQKTRLDILDQLLIPYQTKYIQVSNIDDGYSVIQKMQVRGAPAIAIVGSFSITCELNSVKDGQKNNHGYDVSDLSVFKAALEKRIDYLIKSRPTAVNLVNACTAIKAIVETACTIDDLYAEVLRYSVVLFEDDLKNNYRIGANGVRYIDNELSNFEGPFAVMTICNTGSLATSGHGTALGIIRSLWAKSKANPRNADDKTIQGQKSWLSHVYACETRPYNQGSRLTSYELNFEKIPFSLITDNMPAYLIDSLFSQRVNCPLPSRAPVKFIIVGADRIVTNGDLANKIGTFQLALIASQYDGVKFIGAAPTTTIDYTRDSGDDIVIEQRPANELTSILGGQVDSSDQFVTDSEGKVNLLRIKTATPNIDVWNPAFDVTPNRLIDSIVTEQDYLVKDSHGKFNL
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATRF_ASPFN
Sequence: MADDHRQPEASSNTAANPYNHPVASEHTLGSLNTTSTSETDASADADARWGERNQGDPVSRRGAMEEFEEMRREVTKLSLHRTRSAKDARRRSRAEGRDEEKALEDEQASSTDEYRGGFDLNEFLMGGHLERRTTAGEPAKKVGVAFKNVTVKGVETGASFVRTLPDAVVGTFGPDLYKIICRFVPALHFGKRPPVRDLLHDFSGAVREGEMMLVLGRPGAGCSTFLKTIANDREAFAGVEGEVSYGGLSAEEQHKHFRGEVNYNQEDDQHFPNLTVWQTLKFSLINKTKKHDKASIPIIIDALLKMFGITHTKNTLVGNEYVRGVSGGERKRVSIAETLATKSSVVCWDNSTRGLDASTALDYAKSLRIMTDVSKRTTLVTLYQAGESIYELMDKVLVIDAGRMLYQGPANEAKQYFVDLGFYCPEQSTTADFLTSLCDPNARQFQPGREASTPKTAEELEAIFKQSEAYKQIWNEVCAYEKLLQDTNQEDTRRFQKTVAQSKSKTVSKKSPYTVSIVRQVAACVQREFWLLWGDKTSLYTKYFIIVSNGLIVSSLFYGESLDTSGAFSRGGALFFSILFLVLQLTELMPAVSGRGIVARHKDYAFYRPSAVAIARVVVDFPAIFCMVVPFTIIVYFMTGLDVEASKFFIYFLFVYTTTFCITSLYRMFAALSPTIDDAVRFAGIALNVLILFVGYVIPKQGLIDGSIWFGWLFYVNPLSYSYEAVLTNEFSNRVMSCAPSQLVPQGPGVDPRYQGCALTGSELGKADVAGSRYLQESFQFTRHHLWRNFGVVIAFTVLYLLVTVIAAEVLSFVGGGGGALVFKKSKRSTKLKAQNGKGNDEEQVQNTGDNAALSRGEAKSSSSGEAMQRLSASDRVFTWSNVEYTVPYGNGTRKLLNGVNGYAKPGLMIALMGASGAGKTTLLNTLAQRQKMGVVTGDMLVDGHPLGTEFQRGTGFCEQMDLHDNTATIREALEFSAILRQDRNTPRQEKLDYVDQIIDLLELEDIQDAIIGSLNVEQKKRVTIGVELAAKPSLLLFLDEPTSGLDSQAAFSIVRFLKKLSQAGQAILCTIHQPSSMLIQQFDMVLALNPGGNTFYFGPIGPEGRDVIKYFADRGVVCPPSKNVAEFILETAAKATKKDGRAIDWNEEWRNSEQNRRILDEIQQIREERSKIPIADKGVEYEFAAPTWTQTVLLTERLFRQYWRDPSYYYGKLFVSVIIGIFNGFTFWMLDNSISSMQNRMFSIFLIILIPPIVLNSIVPKFYINRALWEAREYPSRIYGWFAFCTANVVCEIPMAIVSALIYWLLWYYPVGFPTDSSSAGYVFLMSMLFFLFQASWGQWICAFAPSFTVISNVLPFFFVMVNLFNGIVRPYKDYPVFWKYWMYYVNPVTWWLRGVISSVFPSVDIECASKEATHFDPPPGSTCQQYAGNFVSNIAGVGYLVNPDATEDCQYCPFANGTEYMHTLNVHDGDKWRCFGIFLAFVIINWALVYFFIYTVRVRGWSFGMGYLFGGVGVMIEGVKKVFSKKSEKEQN
What is the function of this protein?
Pleiotropic ABC efflux transporter involved in the basal level of azole susceptibility (PubMed:30126960).  Confers resistance to voriconazole (PubMed:30126960).
What are the official names of this protein?
ABC multidrug transporter atrF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CP1A1_MESAU
Sequence: MSSIYGLLNFMSATELLLAITVFCLGFWVVRALRTQVPKGLKTPPGPWGLPILGHVLTLGKNPHLSLTKLSKQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDFYSFTLITNGKSMTFNPDCGPVWAARRRLAQDALKSFSIALDPASASSCYLEEYVIKEADYLISKFQKLMAEVGHFDPDRYLVVSVTNVICAMCFGQRYDHDDQELLSIVNLSNEFGKVTGSGYPPDFIPILRYLPNSSLDAFKDLNKKFYSFMQKSVKEHYRTFEKGHIRDITDSLIEHCQDKSLDENANVQLSDDRVINIIVDLFGAGFDTVTTAISWSLMYLVTNPGVQRKIQEELDTVIGRSRRPRLCDRSQLPYLEAFILETFRHSSFLPFTIPHSTTRDTSLCGFYIPKGHCVFVNQWQINHNQELWGDPNKFRPERFLTSSGTLDKVLSGKVTLFGLGKRKCIGETIGRLEVFLFLAILLQQIEFTVSPGEKVDMTPIYGLTLKHARCEYFQAQTRSSGPQHPQA
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2, as well as D-ring hydroxylated E1 and E2 at the C15alpha and C16alpha positions.  Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation.  Catalyzes the epoxidation of double bonds of certain PUFA.  Converts arachidonic acid toward epoxyeicosatrienoic acid (EET) regioisomers, 8,9-, 11,12-, and 14,15-EET, that function as lipid mediators in the vascular system.  Displays an absolute stereoselectivity in the epoxidation of eicosapentaenoic acid (EPA) producing the 17(R),18(S) enantiomer.  May play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues.  Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid.  May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent).
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1, Cytochrome P-450MC, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, Hydroperoxy icosatetraenoate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm.
Protein: YBIT_ECO57
Sequence: MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFMKILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRIYALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGWKLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMVCTHMADLDYGELRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANASKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPLFKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHEYEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFGKLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRILEITPERVIDFSGNYEDYLRSKGIE
What are the official names of this protein?
Probable ATP-binding protein YbiT.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. YbiT subfamily.
Protein: TARM1_HUMAN
Sequence: MIPKLLSLLCFRLCVGQGDTRGDGSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTKSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEAWYSRNVSPGESEAFKPE
What is the function of this protein?
May act as receptor (By similarity).  Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface (PubMed:26311901).  Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils (By similarity).
What are the official names of this protein?
T-cell-interacting, activating receptor on myeloid cells protein 1, OSCAR-like transcript-2 protein, OLT-2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: KAD_STRP3
Sequence: MNLLIMGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTEMGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLEELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDKPETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDVFADVEKALLELK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5324_HAHCH
Sequence: MKLIIVSGRSGSGKSTALHVLEDMGYYCIDNLPIGLLSPLTQEVLDQGKTQNQQLAVSIDARNLYRDLSDFPSIYAALQAHNIDVEIIYLDANDATLIKRFHATRRKHPLSSKSTSLKEAIAKEKQLLEPIATLANLYIDTSDLSIYQLRDQVKIRVIGHKTQELALLFQSFGFKHGVPSDSDMVFDVRCLPNPYWDTALRGYKGTDQEIIEFLKQHPEPEQMLQHIISFLETWIPHFQNSNRTYMTISIGCTGGQHRSVYICERLGEHFKKKYDNVQVRHKELAQ
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein HCH_05324.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RLMH_PSEU2
Sequence: MRLRLIAVGSRMPKWVEEGWHEYAKRMPSELALELVEIPLNTRGKNADVARFIRQEGEAMLAKVQPGERIVTLEVQGKPWSTEQLAVELDRWRLDARTVNLMVGGPEGLAPEVCARSEQRWSLSPLTLPHPLVRILIGEQMYRAWTVLSGHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_CERSK
Sequence: MPRYALRIEYDGGPFAGWQRQAAQASVQGAIETALGRLELGPHTIAAAGRTDTGVHATGQVAHCDLAREWDPFRLAGALNAHLKPLPVAIVAAARVSEEFHARFSAVERRYLFRLLARRAPEVHDRGRVWRVPHPLDAEAMRAGAAHLVGRHDFTTFRAAGCQAASPIKTLDALTLETVEGANGTEYRFHLRARSFLHNQVRSIVGTLERVGAGAWTPDQVREALDARDRAACGPVCPPQGLYLTGVGYPADPFA
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MEL_APIDO
Sequence: GIGAILKVLSTGLPALISWIKRKRQE
What is the function of this protein?
Main toxin of bee venom with strong hemolytic activity and antimicrobial activity.  It has enhancing effects on bee venom phospholipase A2 activity.  This amphipathic toxin binds to negatively charged membrane surface and forms pore by inserting into lipid bilayers inducing the leakage of ions and molecules and the enhancement of permeability that ultimately leads to cell lysis.  It acts as a voltage-gated pore with higher selectivity for anions over cations.  The ion conductance has been shown to be voltage-dependent.  Self-association of melittin in membranes is promoted by high ionic strength, but not by the presence of negatively charged lipids.  In vivo, intradermal injection into healthy human volunteers produce sharp pain sensation and an inflammatory response.  It produces pain by activating primary nociceptor cells directly and indirectly due to its ability to activate plasma membrane phospholipase A2 and its pore-forming activity.
What are the official names of this protein?
Melittin, MEL, MLT.
What is the protein family that this protein belongs to?
Belongs to the melittin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Alpha-helical peptides form toroidal pores in the prey.
Protein: LEXA_BRASO
Sequence: MLTRKQYELLRFINERLKEAGVPPSFDEMKDALDLRSKSGIHRLITALEERGFIRRLPNRARAIEVIKLPELSQAAGNRRGFTPSVIEGNLGKVRTSTPALEDGERPVAVPVMGRIAAGTPIEALQTRSHTISVPADMLGNGDHYALEVRGDSMVDAGILDGDMALIQRNETADTGDIVVALIDDEEATLKRFRRRGASIALEPANTAYEVRILPPNRVKIQGKLVGLYRKY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: GATC_STRA5
Sequence: MKISEEEVRHVANLSKLRFSDQETKEFASSLSKIVDMIELLNEVDTEGVPVTTTMADRKTVMREDIAQPGHNRDDLFKNVPQHQDYYIKVPAILEDGGDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CO2_PANTR
Sequence: MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRHCCPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPRVLMSVLNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSRWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQHLGDVLNFLPL
What is the function of this protein?
Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a.  C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
What are the official names of this protein?
Complement C2, C3/C5 convertase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HBP1C_WHEAT
Sequence: ESRRGGGGPAAAAAAAGDPRGPMPGFGAPQHTIPTNVNVMQPSRVADLGALAHSAGFRIEDLANFSTNNLFNLKPNTHAYTSDPLQFGNYGKSISPTDLATTAAAAAAVTAVDPQALLQQKGVQPNLVALRTHNNDNWGESSMADTSPRTDTSTDPDIDIDERNQMFEQGQLAAPTASDSSDKSRDKLDHKSLRRLAQNREAARKSRLRKKAYIQNLESSRLKLTQLEQELQRARQQGIFISSSGDQSQSASGNGAVAFDMEYARWLEEHNKHINELRAAANAHAGDDDLRKIVDSIMSQYDEFFRLKGVAAKADVFHVLSGMWKTPAERCFMWLGGFRSSELLKLLAGQLEPLTEQQLTGICNLQQSSQQAEDALSQGMEALQQSLAETLASGSLGPAGSSGNVASYMGQMAMAMGKLGTLENFLRQADNLRLQTLQQMQRILTTRQSARALLAISDYFSRLRALSSLWLARPRE
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'.  Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter.  Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription.  Binds to the hexamer motif 5'-ACGTCA-3' of histone gene promoters.
What are the official names of this protein?
Transcription factor HBP-1b(c1).
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABZ_SYNJB
Sequence: MSSDVSPPPLLSAEAAAQLATAPPVFTTEQILEILPHRYPFLLVDRVVEYQPGQRAVGLKNVTFNEPFFQGHFPNRPIMPGVLIVEAMAQIGGIVLTKLPDVAGRLALFAGIDGVRFRRPVLPGDQLLLSADLLTIRQRRIGKMFCRAQVGGQLVTEGELMFSLVD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_BARHE
Sequence: MSVTSIMDDLKRRMHGAISAFKHELGGLRTGRASASLLEPLTVEAYGSVVHINQVANISVPEPRMLSVSVWDKTMVGAVERAIRDSGLGLNPITDGMNLRIPLPELNEERRKELVKIAHQYAEQARVATRHVRRDGMDNLKKLEKEGEIGQDEAHGLSEKVQKLTDETIADIDKILAVKESEIMHV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INTLP_ALLMI
Sequence: NNQLALKLAATGGSTNSLPALALQNLLNTWEDTSCCSQTSPGQQSWPRDGAQDGLYTLSTADGEIYQTFCDMSTHGGGWTLVASVHENNAHGKCTVGDRWSSQQGNSPLYPEGDGNWANNNIFGSAMGSTSDDYKNPGYYDLQAGDLSVWHVPDRAPLRKEMIESSVLLFYRTGFLSSEGGNLLRLYEKYPVKYGAGSCKVDNGPAVPIVYDFGSAEKTAAYYSPSGRGEFTAGFVQFRVFNNEKAPMALCSGLKVTGCNTEHHCIGGGGFFPEGNPRQCGDFPAFDWDGYGTHQSWSTSREMIESSVLLFYR
What is the function of this protein?
Binds mannan, mannose and, to a lesser degree, D-lactose, N-acetylgalactosamine, N-acetylglucosamine and beta-D-glucose.
What are the official names of this protein?
Intelectin-like protein, Mannose-specific lectin.
What are the subcellular locations of this protein?
Secreted.