PharMolix/UniProtQA huggingface dataset:
Protein: Y3092_BURM9
Sequence: MAGHSKWANIKHKKAAADAKRGKIWTRLIKEIQVAARLGGGDVNSNPRLRLAVDKAADANMPKDNVKRAIDRGVGGADGANYEEIRYEGYGIGGAAIIVDTLTDNRTRTVAEVRHAFSKFGGNMGTDGSVAFMFDHVGQFLFAPGTSEDALMEAALEAGANDVNTNDDGSIEVLCDWQEFSKVKDALEAAGFKAELAEVTMKPQNEVDFTGEDAVKMQKLLDALENLDDVQEVYTNAVVVEE
What are the official names of this protein?
Probable transcriptional regulatory protein BMA10229_A0792.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMF3_YEAST
Sequence: MRSYMQILQKFAKFIGPGILVSVAYMDPGNYATSVSGGAQYKYTLLFSIFISNIFAVLLQCLCVKLGTITGYDLAENCRHNLPKKLNYTLYLFAEVAIIATDLAEVVGTAIALQILFKIPLTWGVLLTVLDVLVILMFYTPNGQSLKKVRVFEFGVGILVIGTCICFVLELFKVSIPDKAELFKGFLPSNIIFKEQQALYISLGILGATVMPHSLYLGSSIVKPRLHDYDLKKYGKVNARPSLSAIKYTLNYAYAELIISLFLIATFVNSAILIVAGATLSGQPEAEDADLLSIYKLLVHYISPAAGLIFALAMLCSGQSAGIICTLAGQIVSEGFLQWSLPPWATRLCTRLIAIVPCLFVTLTMGEKGISDILNFSQVVLSLILPIVSAPLIYFTANRKLMVVHDENGVVRAPADVNAIADETTPLNSKHSKIVDFTNSRLLTYTSVFVWALIGSLNCYLVISYLLGADIHF
What is the function of this protein?
Has a role in controlling the cellular iron ion levels.  Mobilizes vacuolar stores of iron in conditions of low iron levels.
What are the official names of this protein?
Iron transporter SMF3.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PPR78_ARATH
Sequence: MAIRTVSSLVRALYQTPKSQSFRIFSTLLHDPPSPDLVNEISRVLSDHRNPKDDLEHTLVAYSPRVSSNLVEQVLKRCKNLGFPAHRFFLWARRIPDFAHSLESYHILVEILGSSKQFALLWDFLIEAREYNYFEISSKVFWIVFRAYSRANLPSEACRAFNRMVEFGIKPCVDDLDQLLHSLCDKKHVNHAQEFFGKAKGFGIVPSAKTYSILVRGWARIRDASGARKVFDEMLERNCVVDLLAYNALLDALCKSGDVDGGYKMFQEMGNLGLKPDAYSFAIFIHAYCDAGDVHSAYKVLDRMKRYDLVPNVYTFNHIIKTLCKNEKVDDAYLLLDEMIQKGANPDTWTYNSIMAYHCDHCEVNRATKLLSRMDRTKCLPDRHTYNMVLKLLIRIGRFDRATEIWEGMSERKFYPTVATYTVMIHGLVRKKGKLEEACRYFEMMIDEGIPPYSTTVEMLRNRLVGWGQMDVVDVLAGKMERSSSCSVQDMAVEMRGKRRRLGRRSENSEDDDDDFELERDTI
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g52640, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL29_CUTAK
Sequence: MPKLSAAELRQLSGEELRNKVRELKEELFGLRFQSATGQLENTARLREVRKDIARVYTVLQERNLNIVDDPDSTKEA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL16_RHOE4
Sequence: MLIPRRVKHRKQHHPSRSGAAKGGTQVTFGDYGIQALEPAYITNRQIESARIAMTRHIKRGGKIWINIFPDRPLTKKPAETRMGSGKGSPEWWIANVKPGRVLFEMTYPNEEIAREALRRAMHKLPCKCRIVTREEQF
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DMC1_HUMAN
Sequence: MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE
What is the function of this protein?
Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
What are the official names of this protein?
Meiotic recombination protein DMC1/LIM15 homolog.
What is the protein family that this protein belongs to?
Belongs to the RecA family. DMC1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SPEE2_BACAN
Sequence: MPKHRKQSKIKIYRITNYKKDKRSELDSNKFELEQQAVENKQDKQGKQDNQVQSENVVIVPTDSHNLDIWDEISLKEIQAGEHTNLFAEQSNYQNINLLQVSDIRLYLDKQLQFSSVDEQIYHEALVHPIMSKVIDPKRVLILGGGDGLALREVLKYETVLHVDLVDLDGSMIDMARNVPELVSLNKSAFFDNRVNTHVCDAKEFLSSPSSLYDVIIIDFPDPATELLSTLYTSELFARIATFLTEDGAFVCQSNSPADAPLVYWSIGNTIEHAGLTVKSYHTIVPSFGTDWGFHIAANSVYVLDQIEQLYVVPTPRTLPSLLFPLFQFKEEHLEQRNFALLNSESNLILHQCYKKEMEF
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase 2, Putrescine aminopropyltransferase 2, PAPT 2, Spermidine synthase 2, SPDS 2, SPDSY 2.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAA_PECAS
Sequence: MSTPIEAAWQLAKTRYAGLNIDVEAALKQLDQIPVSMHCWQGDDVAGFENTGGPLTGGIQATGNYPGKASTPDELRADLEQAFALIPGPKRLNLHAIYLESAQPVARNEIAPEHFSNWVAWAKRHQLGLDFNPTCFSHPLSADGFTLSHPDEKVRRFWIEHCQASRRISAYFGRELGTPSVMNIWVPDGMKDLTIDRLAFRQRLLSALDEVIAEPLDQTHHIDAVESKLFGIGAESFTVGSSEFCLGYAASRGTALCLDAGHFHPTEVISDKISSAILYVPRLLLHVSRPVRWDSDHVVLLDDETQAIAHEIIRHQLLNRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTETLRKLEQNGDYTARLALLEEQKSLPWQAVWEHYCQRHDVIPGSEWLQQVRQYEETILTQRQG
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_CORJK
Sequence: MSDIEIKGILGKKLGMTQIFDEENRVVPVTVVEAGPCVVTQVRSKETDGYEAVQIAFGEIDPRKVNKPAAGHFKKAGVTPRRHVAEIRVADASSYEVGQDVTVDIFNDVKFVDVTGTTKGKGYAGGMKRHGFAGQGAAHGNQAAHRRVGSIGQAATPGRVFKGKRMAGRMGNDRVTQQNLKLAKVDAESNLLLIKGAVPGVNGGLVVVKTAVKGGAHA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: KDSA_CHLMU
Sequence: MFPNNKMLLIAGPCVIEDNSVFETARRLKEIVAPYSSSVHWIFKSSYDKANRSSLQNYRGPGLKLGLQTLAKIKETFDVEILTDVHSPDEAREAAKVCDIIQVPAFLCRQTDLLVTAGETQAIVNIKKGQFLSPWEMQGPIDKVLSTGNNKIILTERGCSFGYNNLVSDMRSIEVLRRFGFPVIFDGTHSIQLPGALQSQSGGQTEFIPVLTRSAIAAGVHGLFIETHPNPASALSDAASMLSLKDLERLLPSWVQLFTYIQEMDTVSI
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_PSEA6
Sequence: MNMAKMIKVKQTKSAIGRLPKHKATLTGLGLRRIGHVRELEDTPSVRGMINRVFYMVEVVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: THIG_AQUAE
Sequence: MQDWEKLLQDDYLEIAGRKFKSRLIIGSGKFKDFQQTKEVLEASGAEIITVAVRRVNITDPTKENLLDYIDPKKYLILPNTAGCYTAEEAIKTAMMAREATGINWVKLEVIGDQKTLLPDMEETYKAAKVLVKEGFVVLPYIFDDPVFAKKFEDIGCAAVMPLAAPIGSGLGLQNPYNLIFIKEAVSVPVIVDAGIGSATDIPPVMELGVDGVLTNTALAEAKDPIKMAVAMKYATIAGRLAYLAGRMPKRTYAVPSSPTKGVPFKG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_PSEP1
Sequence: MHQLTLAEIARGLADKSFSSEELTGALLARIKQLDPQINSFISITDDLALAQARAADARRAAGETGVLLGAPIAHKDLFCTNGVRTSCGSKMLDNFKAPYDATVVAKLAEAGMVTLGKTNMDEFAMGSANESSHYGAVKNPWNLEHVPGGSSGGSAAAVAARLLPATTGTDTGGSIRQPAALTNLTGLKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALLLQGMAGFDAKDSTSIEEPVPDYSASLNASLQGLRIGLPKEYFGAGLDPRIADLVQASVKELEKLGAVVKEISLPNMQHAIPAYYVIAPAEASSNLSRFDGVRFGYRCEEPKDLTDLYKRSRGEGFGVEVQRRIMVGTYALSAGYYDAYYVKAQQIRRLIKNDFMAAFNDVDLILGPTTPNPAWKLGAKSSDPVAAYLEDVYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHRYQQVTDWHTRAPNGF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: AROB_SHEPW
Sequence: MTKQVLVELGERSYPIVIGQKLLSNGEPLARYLKNKNILIVTNETIAPLYLEKVQAMLSDFSCVTPVILPDGEQYKTLSQMDSIFTSLLQQNLGRDTVLIALGGGVIGDMTGFAAASYQRGIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKYVLIDTDCLSTLPKREFAAGMAEVIKYGIMWDAEFFSWLEDNVEALKALDTHALEYAIGRCCEIKADVVEKDETEQAVRALLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAITSNKLGLVEESIVCRITALFAAFDLPTSAPETMNFEQFIKHMRRDKKVLKGQLRLVLPEGLGRAGIYSNVTDEQLQEVIDCA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VGH_BPPHK
Sequence: MLGSIIGGIGSSLLGGIASGGISSLLNKMFSKMPEHAASSAGLTNGQGTIGMDTDAGIQSAIQGSNVPPAGQLPASNTSGVMADAGNMIRNAGRALLDGTIQAGSDKVKEALIDKLVGGNDAKDRGKATRDYLAAAFPELNPWERAGAGASTAGLESSAQNQQKEMLKMQLDNQKDIAKMQMNNNLQIAGIQSATSRQNTKDSVYAQNEMLQYNQRESQARVASILANTDLTTKQATHEIMRMALTRAQETGQHLTNSQIMALEKKVYAEIGKIHQDTQNSRYGSSQVTAAAKDVTNMITDASSGLADWASQQWDSFFKDGKSDGIPLNTRK
What is the function of this protein?
Minor spike component of the viral shell.  Involved in the ejection of the phage DNA in the host and is injected with the DNA in the periplasmic space of the host.  Involved in the determination of the phage host-range.
What are the official names of this protein?
Minor spike protein, H protein, Pilot protein.
What are the subcellular locations of this protein?
Virion.
Protein: ISPH_ARATH
Sequence: MAVALQFSRLCVRPDTFVRENHLSGSGSLRRRKALSVRCSSGDENAPSPSVVMDSDFDAKVFRKNLTRSDNYNRKGFGHKEETLKLMNREYTSDILETLKTNGYTYSWGDVTVKLAKAYGFCWGVERAVQIAYEARKQFPEERLWITNEIIHNPTVNKRLEDMDVKIIPVEDSKKQFDVVEKDDVVILPAFGAGVDEMYVLNDKKVQIVDTTCPWVTKVWNTVEKHKKGEYTSVIHGKYNHEETIATASFAGKYIIVKNMKEANYVCDYILGGQYDGSSSTKEEFMEKFKYAISKGFDPDNDLVKVGIANQTTMLKGETEEIGRLLETTMMRKYGVENVSGHFISFNTICDATQERQDAIYELVEEKIDLMLVVGGWNSSNTSHLQEISEARGIPSYWIDSEKRIGPGNKIAYKLHYGELVEKENFLPKGPITIGVTSGASTPDKVVEDALVKVFDIKREELLQLA
What is the function of this protein?
Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Is essential for chloroplast development.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, chloroplastic, Protein CHLOROPLAST BIOGENESIS 6.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PLSX_HAEDU
Sequence: MNRLTLALDVMGGDFGPRVTIPALSLALAQQPMLSFVLFGDQYHAIPLLHSLPAEQQQRIRFVHTSRIVDPHVPVRQALRQSKGSSMRLAIEAVVAGEAQACVSGGNTGVLMGLAKWFVEPLVGIDRPALASLIPALNGQASVMLDLGANVEADSKLLLQFAEMGNIFAQSILSLAQPRLALLNIGTEEVKGRYAIQQAHHVLKNRADLHYIGFIESDKLMNHLADVIVCDGFCGNIALKAVEGVASHFLALFKQPKRSFFVDWLSSWWGRLLYHRVYRALQRVNPERHNGATLLGLSSVVVKSHGSAGVNAYFYAINHAIEQIQNRIPVKISAGLQKLHQNL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RL32_MYCPA
Sequence: MAVPKRRMSRANTRSRRAQWKAEKTELVGVTVAGQRHKVPRRLLKAARLGLIDLDRR
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NSP2_ROTBU
Sequence: MAELACFCYPHLENDSYKFIPFNNLAIKCMLTAKVDRKDQDKFYNSIIYGIAPPPQFKKRYNTNDNSRGMNYETSMFNKVAVLICEALNSIKVTQSDVANVLSRVVSVRHLENLVLRRENHQDVLFHSKELLLKSVLIAIGHSKEIETTATAEGGEIVFQNAAFTMWKLTYLEHKLMPILDQNFIEYKITVNEDKPISESHVKELIAELRWQYNKFAVITHGKGHYRVVKYSSVANHADRVYATFKSNNKNGNVLEFNLLDQRIIWQNWYAFTSSMKQGNTLDICKKLLFQKMKRESNPFKGLSTDRKMDEVSQIGI
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RL9_PSEE4
Sequence: MELILLEKVANLGNLGDKVNVKAGYGRNFLLPFGKATVANAANLAAFEERRAELEKAAADKKASAESRAAQLAELEVTITATAGDEGKLFGSIGTHDIADALTASGVEVAKAEVRLPNGTIRQVGEYDVAVHLHSDVEATVRVVVVAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NU4LM_LYCSM
Sequence: MELMKMTLYTTFMITIIALSLQQKHLMLALMCVETMMLIVFTMLVMFNSNSLTVSQTPMPIILLTISVCGAAVGLSLVVAITRTHGNDFLKNLNLL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: OTP_PARLI
Sequence: MERTLAHVPSMELSTEALLVTGGLDNTNKMISSSAVRNDDGTMISQHSDKVSYGTSGAPDGSTPPYPAGGVGEGNGIVGGGGGGGGGGGGGMVGDGTGHSVGSSGSGNDDDKPAKQKRHRTRFTPAQLNELERNFAKTHYPDIFMREEIAMRVGLTESRVQVWFQNRRAKWKKRKKTTNVFRTPGALLPSHGLAQFPSPMNDSFCNFHGQDTRGWPAMSGMTTHMAPHMTTHMPSHQMPLMGGGPGSALALPPSLPRQGLGQSMQQQSVNCSMGQTTGLNTLSMGTNGSMGSMTSMYQPSLGGMTTGSMSSGLSSPSPPNLPVTDSSTDLSCSVSDAGDMWRGTSIASLRRKLEHAASLNGIFR
What is the function of this protein?
Involved in larval skeletal patterning.
What are the official names of this protein?
Homeobox protein orthopedia, Orthopedia-related, PlOtp.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TDH_DEIRA
Sequence: MRALSKQQPGEGIWMIETEVPTPGPNDLLIRIRKGSICGTDVHIYKWDDWASQTVPVPMVVGHEYVGVVAGMGSEVRGFEIGDRVSGEGHVTCGHCRNCRAGRRHLCRNTQGVGVNRPGSFAEYLVLPAFNAFKLPDDIPDDVAAIFDPFGNAVHTALSFDLVGEDVLITGAGPIGCMAAAVARHVGARNVVITDVNDYRLDLARQMGVTRAVNVAREDLWTVATQELDMHEGFDVGMEMSGSGPAFAQMVSVMNNGGKVALLGIPSGEVQIDWNAVIFKMLTIKGIYGREMFETWYKMAALIQSGLDLTPVITHHYGIGDFQQGFDAMLSGQSGKVILDWETEEQSA
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_HBVC3
Sequence: MDIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: HIS1_SALNS
Sequence: MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPAALDGKRIATSYPHLLKRYLDQKGVSFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMAQSKQQLIDKLLTRIQGVIQARESKYIMMHAPSERLEEVIALLPGAERPTILPLAGEQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC62_ARCFU
Sequence: MQVKRIIHINVSFTLMLSWDETLFKNPEVFDPDYIPDELLFRDGQIRQLVSCIKPAMLNSSPINAFCLGPPSTGKTSTIRYVLREAERETGLLYSYIRIPRFKEPYKVFSKIFQDVLGQQSPPSGISKTVLMDRVWSNLDEPLLVVLDDINFLGKNYANEILYEILKAPDEYGVKVGIVAAATDVKFPLLLDPFVGASFHYMEIHYPSYGYAEIEGILRKRVEHGFYEGVFDDGAFRRVVELAYRASDVRYGIYLLKAAGMNAESRGSRKVEERDVEVAHAGESLSFIAKILTALNSEERAVLRMIYSQNAISTGDLYEQVCSEIKMSYRKYYNILEKLERLKLIEISFGEKGRGKTRYVQGKYDAEVVDRAMQLI
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 2.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: DNAA_SHEFN
Sequence: MAVSLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVLYAPNRFVLDWVRDKYINIINQFFTEQMGSNAPKLRFDIGSRPSARPVAPAPVAAKPVNRQTKAQVGTTSFNTQAEPIINPNHRSNINPTYQFDNFVEGKSNQLGKAAALQVSENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQVAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TA2R7_PANPA
Sequence: MADKVQTTLLFLAVGEFSVGILGNAFIGLVNCMDWVKKRKIASIDLILTSLAISRICLLCVILLDCFILVLYPDVYATGKEMRIIDFFWTLTNHLSIWFATCLSIYYFFRIANFFHPLFLWMKWRIDRVISWILLGCVVLSVFISLPATENLNADFRFCVKAKRKTNLTWSCRVNKTQHASTKLFLNLATLLPFCVCLMSFFLLILSLRRHIRRMQLSATGCRDPSTEAHVRALKAVISFLLLFIAYYLSFLVATSSYFMPETELAVIFGESIALIYPSSHSFILILGNNKLRHASLKVIWKVMSILKGRKFQQHKQIGRETMLF
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 7, T2R7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: OPSB_GEKGE
Sequence: MNGTEGINFYVPLSNKTGLVRSPFEYPQYYLADPWKFKVLSFYMFFLIAAGMPLNGLTLFVTFQHKKLRQPLNYILVNLAAANLVTVCCGFTVTFYASWYAYFVFGPIGCAIEGFFATIGGQVALWSLVVLAIERYIVICKPMGNFRFSATHAIMGIAFTWFMALACAGPPLFGWSRFIPEGMQCSCGPDYYTLNPDFHNESYVIYMFIVHFTVPMVVIFFSYGRLVCKVREAAAQQQESATTQKAEKEVTRMVILMVLGFLLAWTPYAATAIWIFTNRGAAFSVTFMTIPAFFSKSSSIYNPIIYVLLNKQFRNCMVTTICCGKNPFGDEDVSSSVSQSKTEVSSVSSSQVAPA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Blue-sensitive opsin P467, Blue photoreceptor pigment.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.