PharMolix/UniProtQA huggingface dataset:
Protein: ATPF_YERPN
Sequence: MNLNATILGQAIAFVLFVIFCMKYVWPPIMAAIEKRQQEIADGLSSAERAKKDLDLAQANATDQLKKAKAEAQVIIEQASKRKAQILDEAKAEAEQERNKIVAQAQAEIDAERKRAREELRKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL7_FRATF
Sequence: MAITKEDILNAVAEMSVMDVCDLVKMMEDKFGVSAAAAVAVAAGPVAGPVEAAEEKTEFDVVLVDAGSNKIAAIKAVRGATGLGLKEAKDAVEGTPFTVKEAASKEEAEALKKQLEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: MEP5_TRIVH
Sequence: MHGLLLAAAGLLSLPLHVLAHPQPSTNLAGRGVDLDAYRMADRSSYMSSDDMKLKQPAIASLSGGNYVDTATEVVKRMMPGMTFRMVDDHYVGESGISHVYFRQTMHGMDIDNADFNVNIGKDGKVLSVGHSFYTGPAPDKAPVEKRDFSDPMQAFHGACKALNLSINSDKATIQTMNEHEVMFMGTSGAMSDPQGKLCYMAKEDGTLALTWRVETDMGDNWLLSYVDAKETDKVHNVVDYVSHATYQVYKWPIPDPTEGKREIVENPWNLKTSPFTWISDGKTNYTTTRGNNAIAQANFDGGEDYLNNYRPDSKNLKFEYPYAPNMSPPKSYIDASVTQLFYSANMVHDLYYMLGFTEKAGNFQVNNHGQGGKGNDFVILNAQDGSGTNNANFATPPDGKPGRMRVYIWTKAKPSRGSSFEAGTVIHEYTHGLSNRLCGGPANAGCLNGMESGGMGEGWGDFFATAIRLKPNDNRNSNYVHGEWVNNSPKGNRLYPYSTNLQTNPLVYTSCNKYNEVHAIGTVWCSILYEVLWNLIDKHGKNDGPTPVFENGVPNDGKYLALKLVLDGMAIQPCKPTFVQARDAIIDADMNLTKGSNKCELWKAFAKRGLGVGAKYDPKNRTGSKAVPKECQ
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Probable extracellular metalloproteinase 5, Fungalysin MEP5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEPA_CHLL2
Sequence: MALPSQEVSRTRNFCIIAHIDHGKSTLADRLLEVTHTLDRTQMSSAQVLDDMDLEKERGITIKSHAVQMKFKAEDGQEYILNLIDTPGHVDFSYEVSRSLAACEGALLIVDATQGVEAQTIANLYLAIEAGLEIIPVMNKIDLPSSDVEGVASQIIDLIGVERDEILQVSAKAGTGIDKLMDAIIARIPSPKDNKHLPLRALIFDSVFDPYRGAVVYLRIVDGVLNKGDRVRFFANDHIYTADEIGTMSLKRQPKETLASGNVGYLICSIKDVKDAKVGDTVTHADTPASEPLSGYKDVKPMVYSGLYPVNSNEFEDLRESLEKLSLNDASLVYTPETSVALGFGFRCGFLGLLHMEIIQERLEREYGVNIITTVPNVEYRVILTNSDVIEVDNPSKMPDTTKINHVEEPYVSMQIITLSEYIGNIMKLGMERRGEYKNTDYLDSSRVIMHFEFPLGEIVFDFHDKLKSISKGYASMDYEYIGYRESDLVKLDVLLNGEPVDALSIIVHRSKAYEWGRKLCQKLKGIIPKQMYEVAIQAAIGSRVISRETISAMRKNVLAKCYGGDISRKRKLLEKQKEGKKRMKQVGRVEVPQEAFLAILNIDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL18_ESCF3
Sequence: MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CHLN_CHLVU
Sequence: MTNSKLTETLTFECETGNYHTFCPISCVAWLYQKIEDSFFLVIGTKTCGYFLQNALGVMIFAEPRYAMAELEEADISAQLNDYKELKRLCLQIKQDRNPSVIVWIGTCTTEIIKMDLEGMAPRLEAEIQTPIVVARANGLDYAFTQGEDTVLAAMVQRCPSNAPEQNQIEKKSLVLFGSLPTNVATQLNLELERCGIQVAGWLPSQRYADLPVLNQNVYVCGINPFLSRTATTLMRRRKCKLISAPFPIGPDGTRAWLEKICSVFNVAPINLIERERLIWDSLEDYITLLRGKSVFFMGDNLLEISLARFLVRCGMIVYEIGIPYLDKRFQSAELQLLEKTCSEMNVAMPRIVEKPDNYNQIQRIRELQPDLAITGMAHANPLEARGINTKWSVEFTFAQIHGFTNARDILELVTRPLRRNKALENLGWNQLVKM
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LEUD_LACE2
Sequence: MNEKFSGKVWVLGDDIDTDIIIPTEYLALKTVEDMKPYAFSPLRPELAGQIKPGDIIVAGKNFGCGSSREQAPEVIKALGIKCVIAKSYARIFFRNSINNGLLLIENADLHDEVTEGDTIDVEVNAKITHNGKAYPIASLPDNLVDILNAGGLVKAMRKLNGLD
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: Y556_ARCFU
Sequence: MVVVDARGSYCPGPLMEMIKTLKQVEVGEVVEVLSSDESSAKDIPEWVKKAGHELVEVKKEEDYWRIVVKKLK
What are the official names of this protein?
Putative sulfur carrier protein AF_0556.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
Protein: YCBJ_SHIFL
Sequence: MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLMARSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMTHEEHPGPDVLLLERMRGVSVEAPARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYRQHVEVLWTTLNQFNNTGLTMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMVGPGLMLWAPREYELFRLMDNSLAEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVNTGRFSRRNFDLASKSLLPWLA
What are the official names of this protein?
Uncharacterized protein YcbJ.
Protein: LUXS_YERPN
Sequence: MPLLDSFTVDHTIMKAPAVRVAKTMKTPHGDEITVFDLRFCVPNKEVMPEKGIHTLEHLFAGFMRDHLNGDGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVTDQRKIPELNEYQCGTYHMHSLEEAQSIAKDILDRDVRINHNEELALPKEKLTELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: MRAZ_SHESR
Sequence: MFRGASAINLDTKGRIAIPVRYREPLQLEHQGRIVITVDIQSACLLLYPLHEWELIEAKLLKLSDTDKTQRSLKRMLLGYAHEVELDGNGRILLPPPLRQYANLDKRIMLVGQLNKFELWDEQAWLQQIDECQETIRSEELANNERLADFSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GRA3_CLAGR
Sequence: MISEIAKLAALVLTNTVKVDDFLQSSKLPPPTFHEDGPIDLGLSPEVEAARVAAIESSLRLHDLLXGPVELIRPTVNAXSLEAIYKYDVASKVPIHGEIPIIELAXQCKMNEPDLRRILRFAIIHHRVFQEPRKGIITHSAASRRLVEDSAARDGLGLQFDDAWQSFARGFSLAHNTDKSVFEYMEAHPEKAKRFAGAMSSFSSYRGHGPEYLARGFPWASLGTKTVVDVGGSEGKYSIALAKSFPQLKFIVQDLPAVVRAVNAKRPIPLELEDRVTFMEHDMFTEQPVSADVYMFRFVFHDWPDKYVVNILRRLIPALKPGARIIISDSILPEPNTLSELYERKIRALDMVMLSFFNSRERERDDWERVCQEVDPRFKFVDAWVPEGAALGIIEAVWQPEPTMEXPKAIESDESSSTGVXDSAKGIKGMESNGRNGXISVTCVDDVDVN
What is the function of this protein?
Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of orcinol depsidone grayanic acid (GRA), the only major secondary metabolite known in C. grayi (PubMed:21289108).  The first step consists in the ring and depside synthesis by PKS16 leading to 4-O-demethylsphaerophorin, involving different orcinol-like rings, one with acetyl CoA and the other with octanoyl CoA as the starter (Probable).  Further depsidone formation by the GRA cluster-specific cytochrome P450 leads to 4-O-demethylgrayanic acid (Probable).  Finally, the cluster specific O-methyltransferase probably converts the 4-O-demethylgrayanic acid into grayanic acid (Probable).
What are the official names of this protein?
Grayanic acid biosynthesis cluster O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: GRZ2_RAT
Sequence: MFLFLIFLVAVLPVNTEGGEIVWGTESKPHSRPYMASLMFYYGNSYRHYCGGFLVAKDIVMTAAHCNESNIKVILGAHNIKKRENTQVFSVVKAKPHENYDSHSLFNDIMLLKLERKAQLNGVVKTIALPRSQDWVKPGQVCTVAGWGRLANCTLSNTLQEVNLEVQKGQKCQGMSEDYNDSIQLCVGNPSEGKATGKGDSGGPFVCDGVAQGIVSRRLCTGTLPRVFTRISTFIPWIQKTMKLLQQP
What is the function of this protein?
This enzyme is necessary for target cell lysis in cell-mediated immune responses.
What are the official names of this protein?
Granzyme-like protein 2, GLP-2, Granzyme-like protein II, GLP II, Mast cell protease 10, rMCP-10, Mast cell protease X, rMCP-X.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
Protein: TRMA_ALISL
Sequence: MTQPVMNPENYQVQLDEKTEALSAMFSEFDVPELEVFSSPAENYRMRAEFRIWHEGDDMYYVMFDQKTKEKYRVDYFLPATRLINDLMPLLAEAIKGSKTLRYKMFQVDFLSTLSGEILVSMLYHRQLDDAWKEEAAVLKQQLNEKGFNLNLIGRARKMKIVLDQEFVIEKLKVNDDILTYKQVENSFTQPNGVVAQKMLEWAVDCTQDSQGDLLELYCGNGNFSLALAKNFDRVLATELAKPSVESAQYNIAANNIDNVQIVRMSAEDFTDAMEGKREFRRLKDQNVDLKSYNCNTIFVDPPRSGMDEGTCKMVQGYERIMYISCNPDTLKENLAILSKTHNITRFALFDQFPYTHHMEAGIFLERK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: PGLR_BRANA
Sequence: MGSYLGIYTILVLCLLGYSANAEVFTAGGPPNSDITAAVLKAFTSACQAPAPSQVLIPKGDFKLGETVMTGPCKSPIEFTLQGNVKTDGGSTQGKDRWVVFEKINGFKLNGGGTFDGEGNAAWKANNCHKTFECKKLPISVRFDFVDNAEIKDVTSLDAKNFHFNVISGKNMTFDNIKIIAPAESPNTDGIHLGRCEGVKILNTKIATGDDCISVGDGMKNLLIEKVVCGPGHGISVGSLGRYGWEQDVTDITVKNCTLEGTSNGLRIKTWPSAACTTTAAGIHFEDIILNKVSNPILIDQEYCPWNQCNKNKPSTIKLVDITFRNIRGTSENKDAVKLLCSKGHPCENVEIGDINIEYTGPDGPPTFECTNVTPKLVGAQNPKACVGPVVKAPGKE
What is the function of this protein?
May function in depolymerizing pectin during pollen development, germination, and tube growth.
What are the official names of this protein?
Polygalacturonase, PG, Pectinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: CML12_ARATH
Sequence: MADKLTDDQITEYRESFRLFDKNGDGSITKKELGTMMRSIGEKPTKADLQDLMNEADLDGDGTIDFPEFLCVMAKNQGHDQAPRHTKKTMADKLTDDQITEYRESFRLFDKNGDGSITKKELRTVMFSLGKNRTKADLQDMMNEVDLDGDGTIDFPEFLYLMAKNQGHDQAPRHTKKTMVDYQLTDDQILEFREAFRVFDKNGDGYITVNELRTTMRSLGETQTKAELQDMINEADADGDGTISFSEFVCVMTGKMIDTQSKKETYRVVNQGQGQVQRHTRNDRAGGTNWERDIAVGVASNIIASPISDFMKDRFKDLFEALLS
What is the function of this protein?
Potential calcium sensor that binds calcium in vitro.
What are the official names of this protein?
Calmodulin-like protein 12, Touch-induced calmodulin-related protein 3.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: PPDC_ECOLI
Sequence: MSASLKNQQGFSLPEVMLAMVLMVMIVTALSGFQRTLMNSLASRNQYQQLWRHGWQQTQLRAISPPANWQVNRMQTSQAGCVSISVTLVSPGGREGEMTRLHCPNRQ
What is the function of this protein?
Not yet known.
What are the official names of this protein?
Prepilin peptidase-dependent protein C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AROE_LATSS
Sequence: MISGYTALYGLIAHPAQHSLSPFIHNTGFHQIQMDARYAVFDSQATPAAITSAIKTLGIRGVNLSMPYKQSLVPLVDNLTSTAKLVGAINTIKNEAGRLTATNTDGDGFWCALQKAHPQRRYRSVTILGAGGAALAVIEAAVRYGVQQVTVFKRANATYDSVIQRLAQISLASGLQIIVEPYDDQLALATALQNADCLINATNIGMTATPGNPLPINLLQYLPEDSLVADLIYAPRETAFLKTAQKAHYQIQNGLGMLIEQAALSFEFWTNESMATMPIYQHLTGGNDAS
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: GCH1_CITK8
Sequence: MSSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKRLISGHMTEIMQLLNLDLSDDSLMETPHRIAKMYVDEIFSGLDYANFPKITVIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILTALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRQEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RL30_BEUC1
Sequence: MAQLKVTQTRSTIGGKQNQRETLATLGLGRIGKSTVQEDTPGVRGMIRVVAHLVSVEEVDES
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PRMA_LACLS
Sequence: MNNWNSITIKISREAEEAISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSELVDITAYYPENMPIVELKAEIEHKIANLADYFSLTGLSVTTNNLSETNWAEAWKKYFEPARITHDLTIVPSWTKDYLATGSEKLIRLDPGMAFGTGTHPTTKMSLYALEQVLRGGETLLDVGTGSGVLSVAATYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADVIVANILADILVLMTDDAFRLVKEEGYLIMSGIIADKADMVIASAENAGFFLETRLIQGEWNCLIFKKTENREGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSHC_FLAJ1
Sequence: MPTDCISYQTSGYFSKLIQDYLDQKSELKTLYNHFPTLENFEKQIAEKASNFDNHNRIALVNTLKKQYQNIEISDSTKQNIELLALENTFTITTGHQLNLFSGPLYFLYKIISTINLTKELKSKYPSYNFVPVYWMATEDHDFEEINYFNFKGKKFRWNKESNGPVGRLSTEGLAEFLDIYSLELGSSTNANTLKKLFEDTYLKHDNLADATRFLANSLFANYGLVIIDADDADLKRAFIPYAKEELEKQTSYKAVQETIEQLKEYTVQVNPREINLFYIEDNLRERIIFEEDKYFVNNTKISFSKDQILSELENHPEKFSPNVIMRPLYQEIILPNLCYIGGGGEIAYWLELKSFFDAVNITFPMILVRNSVLLATEKQAKKADQLNLSWKDLFTKQENLVNAITHKISAFPIDLTPQKEILKTQFQYLYELAAQTDKSFSGAVKAQEVKQTKGLENLEKRLLKAQKRNLSDQLQRVIDLQCELFPNNSLQERQSNFSEFYLEKGEQLVPLLLQKLKPLEMNFNIITI
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: GRAP2_MOUSE
Sequence: MEATAKFDFMASGEDELSFRTGDILKILSNQEEWLKAELGSQEGYVPKNFIDIEFPEWFHEGLSRHQAENLLMGKDIGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDTKGNYFLWTEKFPSLNKLVDYYRTTSISKQKQVFLRDGTQDQGHRGNSLDRRSQGGPHPSGTVGEEIRPSVNRKLSDHLPLGPQQFHPHQQPSPQFTPGPQPPQQQRYLQHFHQDRRGGSLDINDGHCGLGSEVNATLMHRRHTDPVQLQAAGRVRWARALYDFEALEEDELGFRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMMR
What is the function of this protein?
Interacts with SLP-76 to regulate NF-AT activation.  Binds to tyrosine-phosphorylated shc.
What are the official names of this protein?
GRB2-related adaptor protein 2, Adapter protein GRID, GADS protein, GRB-2-like protein, GRB2L, GRB-2-related monocytic adapter protein, MONA, Monocytic adapter, GRBLG, Growth factor receptor-binding protein, Hematopoietic cell-associated adaptor protein GrpL.
What is the protein family that this protein belongs to?
Belongs to the GRB2/sem-5/DRK family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endosome.
Protein: ATPL_STAS1
Sequence: MNLIAAAIAIGLSALGAGIGNGLIVSRTVEGVARQPEARGQLMGIMFIGIGLVEALPIIGVVIAFMSL
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NXPH4_RAT
Sequence: MRLLPEWLLLLFGPWLLRKVISGQIVESGRPQYLDLRPAMAGGGARGQQLPVPASSEGLNPVRSWSWAWPANHTGALARPGAAGGPPVPRTKRKPSIKAARAKKIFGWGDFYFRVHTLKFSLLVTGKIVDHVNGTFSVYFRHNSSSLGNLSVSIVPPSKRVEFGGVWLPGPAPHPLQSTLALEGVLPGLGPPLGMAGQGLGGNLGGALAGPLGGALGVPGAKESRAFNCHVEYEKTNRARKHRPCLYDPSQVCFTEHTQSQAAWLCAKPFKVICIFVSFLSFDYKLVQKVCPDYNFQSEHPYFG
What is the function of this protein?
May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.
What are the official names of this protein?
Neurexophilin-4.
What is the protein family that this protein belongs to?
Belongs to the neurexophilin family.
What are the subcellular locations of this protein?
Secreted.
Protein: APOE_PHYMC
Sequence: MKVLWVALVITLLAGCQAEEVKPAPEPEVQLGQEWPGWQGSQPWEQALGRFWDYLRWVQTLSDQVQEELLSTQVIQELTVLMDETMKEVKAYREELEEQLGPVAQETQARVSKELQAAQARLASDMQDVRGRLAQYRSEVQAMMGHTTDELRDRLASHLRKLRKRLLRDAEDLQKRLAVYRAGALEGSERSVSAIRERLGPLVEQGRARAATVGTLASQTLRERAEAWHQKLRGRVEEMGTQARDHLEEMREQLDEVRAKVEEQGTQMRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQLAMATSSTSAPSENH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: SPEH_PSEAE
Sequence: MAIQPLRLDPITVLGKQLVIELFDCVDQRFDDIQWIEESMLEAARQANATIITSAFHKFSPIGISGVVVIAESHLAIHTWPEYGYAAVDVFTCGDVLDGAQAVRVLSERLGSRRHLISSMDRGLGGHRLGLLSRSLAGNGPVDEDSPTLRWALGQGTGVA
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: PYR1_YEAST
Sequence: MATIAPTAPITPPMESTGDRLVTLELKDGTVLQGYSFGAEKSVAGELVFQTGMVGYPESVTDPSYEGQILVITYPLVGNYGVPDMHLRDELVEELPRYFESNRIHIAGLVISHYTDEYSHYLAKSSLGKWLQNEGIPAVYGVDTRSLTKHLRDAGSMLGRLSLEKSGSDRTISRSSSWRSAFDVPEWVDPNVQNLVSKVSINEPKLYVPPADNKHIELQTGPDGKVLRILAIDVGMKYNQIRCFIKRGVELKVVPWNYDFTKEDYDGLFISNGPGDPSVLDDLSQRLSNVLEAKKTPVFGICLGHQLIARAAGASTLKLKFGNRGHNIPCTSTISGRCYITSQNHGFAVDVDTLTSGWKPLFVNANDDSNEGIYHSELPYFSVQFHPESTPGPRDTEFLFDVFIQAVKEFKYTQVLKPIAFPGGLLEDNVKAHPRIEAKKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYFVPVTAEFVRKVILHERPDAIYVTFGGQTALSVGIAMKDEFEALGVKVLGTPIDTIITTEDRELFSNAIDEINEKCAKSQAANSVDEALAAVKEIGFPVIVRAAYALGGLGSGFANNEKELVDLCNVAFSSSPQVLVEKSMKGWKEVEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPVSKDYCIIEVNARLSRSSALASKATGYPLAYTAAKLGLNIPLNEVKNSVTKSTCACFEPSLDYCVVKMPRWDLKKFTRVSTELSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYANLGFNETDLDIDIDYELNNPTDMRVFAIANAFAKKGYSVDKVWEMTRIDKWFLNKLHDLVQFAEKISSFGTKEELPSLVLRQAKQLGFDDRQIARFLDSNEVAIRRLRKEYGITPFVKQIDTVAAEFPAYTNYLYMTYNADSHDLSFDDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRANNIKTIMVNYNPETVSTDYDEADRLYFETINLERVLDIYEIENSSGVVVSMGGQTSNNIAMTLHRENVKILGTSPDMIDSAENRYKFSRMLDQIGVDQPAWKELTSMDEAESFAEKVGYPVLVRPSYVLSGAAMNTVYSKNDLESYLNQAVEVSRDYPVVITKYIENAKEIEMDAVARNGELVMHVVSEHVENAGVHSGDATLIVPPQDLAPETVDRIVVATAKIGKALKITGPYNIQFIAKDNEIKVIECNVRASRSFPFISKVVGVNLIELATKAIMGLPLTPYPVEKLPDDYVAVKVPQFSFPRLAGADPVLGVEMASTGEVATFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLSSVQKLYNMGYKLFATSGTADFLSEHGIAVQYLEVLNKDDDDQKSEYSLTQHLANNEIDLYINLPSANRFRRPASYVSKGYKTRRLAVDYSVPLVTNVKCAKLLIEAISRNITLDVSERDAQTSHRTITLPGLINIATYVPNASHVIKGPAELKETTRLFLESGFTYCQLMPRSISGPVITDVASLKAANSVSQDSSYTDFSFTIAGTAHNAHSVTQSASKVTALFLPLRELKNKITAVAELLNQWPTEKQVIAEAKTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKDPRVTCDVNIYSLFIAQDDYPEAVFLPTKEDQEFFWNNLDSIDAFSVGALPVALANVTGNKVDVGMGIKDSLPLLLAAVEEGKLTIDDIVLRLHDNPAKIFNIPTQDSVVEIDLDYSFRRNKRWSPFNKDMNGGIERVVYNGETLVLSGELVSPGAKGKCIVNPSPASITASAELQSTSAKRRFSITEEAIADNLDAAEDAIPEQPLEQKLMSSRPPRELVAPGAIQNLIRSNNPFRGRHILSIKQFKRSDFHVLFAVAQELRAAVAREGVLDLMKGHVITTIFFEPSTRTCSSFIAAMERLGGRIVNVNPLVSSVKKGETLQDTIRTLACYSDAIVMRHSEEMSVHIAAKYSPVPIINGGNGSREHPTQAFLDLFTIREEIGTVNGITVTFMGDLKHGRTVHSLCRLLMHYQVRINLVSPPELRLPEGLREELRKAGLLGVESIELTPHIISKTDVLYCTRVQEERFNSPEEYARLKDTYIVDNKILAHAKENMAIMHPLPRVNEIKEEVDYDHRAAYFRQMKYGLFVRMALLAMVMGVDM
What is the function of this protein?
This protein is a 'fusion' protein encoding three enzymatic activities of the pyrimidine pathway (GATase, CPSase, and ATCase).
What are the official names of this protein?
Protein URA2.
What is the protein family that this protein belongs to?
In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.