PharMolix/UniProtQA huggingface dataset:
Protein: TRPA_FRAT1
Sequence: MTNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDPLADGPTIQEANIRALESGITPKDCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDASESTLKQISELGSGYTYLLSRVGVTGTETAANMPVEDVLTKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVKIIQNNISNKQKMLNELTYFVKEMKAATLN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RL22_FRATN
Sequence: MEVQAKLKFARISAQKCRLVADQIRGLPVEQAINLLTFSNKKAAVLIKGVLNSAVANAEHNDGMDVDSLVVSTIFVDEGPTMKRFEARAKGRGNRILKRTSHITVKVAEKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DEF_LISW6
Sequence: MLTMDDIVREGHPALREVASEVTFPLSDEEKKLGHDMLEFLINSQDEELAEKYGLRGGVGIAAPQLAVTKRILAIHVHDEKDRLYSYVLYNPKIRSHSVQQACLSGGEGCLSVDREVPGYVVRSERVTIDAFDENGIPLKLRFKDYPAIVVQHEIDHLNGIMFYDHINKENPSYLPPDVDVFG
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: TMX1_HUMAN
Sequence: MAPSGSLAVPLAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDKEWKSIEPVSSWFGPGSVLMSSMSALFQLSMWIRTCHNYFIEDLGLPVWGSYTVFALATLFSGLLLGLCMIFVADCLCPSKRRRPQPYPYPSKKLLSESAQPLKKVEEEQEADEEDVSEEEAESKEGTNKDFPQNAIRQRSLGPSLATDKS
What is the function of this protein?
May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin-related transmembrane protein 1, Thioredoxin domain-containing protein 1, Transmembrane Trx-related protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Predominantly found in the endoplasmic reticulum.
Protein: PDRP_ANAMF
Sequence: MRNKAVLDLHLVSDSTCETVIAVARSAVEHFKSLEVNEFVWSLVGSKRQVDKVMLNINPERHNLIMYTVVDDDLRKYLKEKATAQSVRCIPVLAHVIREISCYLQVTKDPNAHPHKLGDEYFNRIDAINYTISHDDGQNLWDIDQADIIIVGVSRTSKSPTSIYLAYRGYRVVNIPLVCSVQLPVDPATIADKLVVGLTIDADRLIQIRRNRLISMKHQENCNYVSYEQVVEEINEMKKICAKNRWPTIDVTQKSVEEIAATIIQFFNRKNNRTGDALY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: LEUC_BACFR
Sequence: MNTLFDKIWDAHVVTTVEDGPTQLYIDRLYCHEVTSPQAFAGLRARGIKVFRPEKVYCMPDHNTPTHDQDKPIEDPVSKTQVDTLTKNAADFGLTHYGMMDKRNGIIHVVGPERGLTLPGMTIVCGDSHTSTHGAMGAVAFGIGTSEVEMVLASQCILQSRPKTMRITVDGKLGKGVTAKDIALYMMSKMTTSGATGYFVEYAGEAIRSLTMEGRLTLCNLSIEMGARGGMIAPDEVTFEYIKGRENAPQGEEWDQAVQYWKTLKSEDDAVFDKEVHFDAADIEPMITYGTNPGMGMGITQHIPTTDGMNETTKASFLKSLDYMGFQPGEALLGKKIDYVFLGACTNGRIEDFRAFASIVKGHQKAEHVIAWLVPGSWMVDAQIREEGLDKILEDAGFAIRQPGCSACLAMNDDKIPAGKYSVSTSNRNFEGRQGPGARTLLASPLVAAAAAITGVIADPRELM
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MURB_THEFY
Sequence: MTTSFARNVPLADYTTLGLGGPAARFCSVASTDELIATVRDVDRSGDPLLVLGGGSNLVVADEGFAGTVIQVDSSDLSYTEVDDTVVRVRVDAGMEWDSFVARCVDEGLSGVEALSGIPGRVGATPIQNVGAYGQDISQTVVEVTVYDRAADRTRVLSAAECGFAYRTSIFKGRDRYVVCDVVFELTRSKLSRPIRYAELARSLGVSQGDQVPLADVRDAVLSLRRSKGMVLDPADPDTRSAGSFFTNPILSADEFARFTQRVAEVLGPEVTPPAYPDGDGRVKTSAAWLIERAGFPKGYGTGPVGISTKHTLALTNRGGATTADLLALAREVRAGVARVFGITLVNEPVMIGVTL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNE_SHIBS
Sequence: MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y392_HAEIN
Sequence: MDIFFVISGFLITGIIITEIQQNSFSLKQFYTRRIKRIYPAFITVMALVSFIASAIFIYNDFNKLRKTIELAIAFLSNFYLGLTQGYFDLSANENPVLHIWSLAVEGQYYLIFPLILILAYKKFREVKVLFIITLILFFILLATSFVSANFYKEVLHQPNIYYLSNLRFPELLVGSLLAIYHNLSNKVQLSKQVNNILAILSTLLLFSCLFLMNNNIAFIPGITLILPCIFTALIIHTTSQNNIR
What are the official names of this protein?
Uncharacterized protein HI_0392.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y876_ALIFM
Sequence: MSENGFLFRFRDGQTYMDTWPERKELAPMFPEQRVIKATKFAVKVMPAVAVISVLTQMVFNNTAGLPQAIIIALFAISMPLQGFWWLGNRANTKLPPALASWYRELYQKIIESGAALEPMKSQPRYKELANILNKAFKQLDKTALERWF
What are the official names of this protein?
UPF0208 membrane protein VFMJ11_0876.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPH_AZOSB
Sequence: MDNNEILLANPRGFCAGVERAIEIVERALQRFGAPIYVRHEVVHNKFVVDDLRAKGAVFVEELDEVPTGNTVIFSAHGVSQAVREEADKRGLRVFDATCPLVTKVHIEVGRMREQGRELVMIGHKGHPEVEGTMGQVKDGIHLVETAADVANLQVADPDKLAYVTQTTLSVDDAAAIVTALRERFPNIMGPKKDDICYATQNRQDAVKFMTPHADVVFVVGSKNSSNSNRLREVAELRGVPAYLVDNAAGIDPAWIVGKRRIGVTAGASAPEVLVAEVIERLKALSGASVRNLDGVPEKVTFPLPKELQEAR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: FLGI_ECOSE
Sequence: MVIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDARAIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: ENO_MYCTU
Sequence: MPIIEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRWGAEVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALALDAAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASIGDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTMISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFACETK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RIMP_PARP8
Sequence: MQLTELIETTVVGLGYELVDLERTGRGMLCIYIDQPAGIAIEDCEKVTRQLQHVLTVENIDYERLEVSSPGLDRPLKKLADFERFAGSEAVITLKKPLDGRKSYRGILHAPEGETIGLEFEGKEGAAMLDFTLADIDKARLVPKVDFRSRKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSJ_ECOHS
Sequence: MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLTAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQTAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDSPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: SYC_BURA4
Sequence: MESLRIYNTLARDKQVFVPRQSGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIGYRVTYVRNITDIDDKIIRRALENGETIKSLTDRFIGAMHEDEAALGIQRPDIEPRATQFIPQMLGMIEKLETNGYAYQAADGDVNYSVRKFANYGKLSGKSLDDLRAGERVAANDAKEDPLDFVLWKRAKADDPQGASWASKYGMGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHHENEIAQSEGATGQTFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVMRFFIVRTHYRSPLNYSDVHLDDARASLTRLYTALKDVQPDALALDWNEPHAQRFAAAMNDDINTPVAVATLFELAGEVNRTCDASLARQLKQLAGLLGLLGREPRAFLQQATGAAQAGGLAADEIEAKIAARVAAKQAKDYAEADRIRAELLDAGIALEDKPGGSTEWRRV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_BORPA
Sequence: MLHIYNTLSRTKEPFKPAHAGQVRMYVCGMTVYDYCHLGHARMLVAFDVVQRWLRASGLAVDYVRNITDIDDKIIRRAVETGRRIGEVTEYYIAAMHADERALGVQPPDREPRATQYVGEMLDIIGRLESKGLAYRAEDGDVNYAVRGFADYGKLSGKSLDDLRAGERVAVGSAKRDPLDFVLWKSAKPQEPDDTKWESPYGLGRPGWHIECSAMSKTLLGLPLDIHGGGPDLKFPHHENEIAQTEGAFGGALANVWMHCGPLMVDADKMSKSLGNFRTIRQTIAQGALSDTQAEYAVNPREAEMLRFFIVRNHYRSPQNYAPDNLVDAQNALDRLYQALQNTAADGQGVDWSEPQAQAFKAAMDDDFNSSGAVAALFELASEANRTGSARAAGQLKALGAVLGLLQQDPPAYFQSPTRYSAAAREQGAPAAALDAAAIEARIAERAAAKAARDFARADAIRAELRAAGVELDDKPGGLTQWRRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_MYCLE
Sequence: MPTYAPKAGDTTCSWYVIDATDVVLGRLAAVAATLLRGKHKPTFAPNVDGGDFVIVINADKVAISGDKVQHKMVYRHSGYPGGLRKRTIGELMQKHPDRVVEKAIVGMLPKNKLSRQIQRKLRVYAGPDHPHSAQQPVPFEIKQVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TPIS_PARD8
Sequence: MRKNIVAGNWKMNTTLAEGLALAKGLDEALKGKTPNCDVIIGTPFTHLASVAAAIDTNKIGVAAENCADKEKGAYTGEVSAAMVASTGAKYVILGHSERRAYYHETPEILKTKVELALANGLTPIFCIGEVLEEREAGKHFEVVDAQIAGSLFDLSAEDFGKIILAYEPVWAIGTGKTASAEQAEEIHAHIRATLAAKYGNEVADNCTILYGGSCNAGNAKELFAKPNVDGGLIGGASLAVDKFMPIIEAF
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLM4_YEAST
Sequence: MVMLHSKNVKGFLENTLKPYDLHSVDFKTSSLQSSMIITATNGGILSYATSNNDVPKNSINEINSVNNLKMMSLLIKDKWSEDENDTEEQHSNSCYPVEIDSFKTKIYTYEMEDLHTCVAQIPNSDLLLLFIAEGSFPYGLLVIKIERAMRELTDLFGYKLG
What is the function of this protein?
Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome (PubMed:16732272).  Component of the EGO complex, a complex involved in the regulation of microautophagy (PubMed:15989961).
What are the official names of this protein?
Protein SLM4, EGO complex subunit 3, GSE complex subunit 1.
Protein: MOAC_ACICJ
Sequence: MSRLTHIDERGAARMVDVSGKAETAREATAACHVTMRAETLALVTEGTAKKGDVLATARIAGIMAAKRTSELIPLCHPLAIAGVTLELEPDAALPGIRIAATVKTTGPTGVEMEALTAASVAALTVYDMLKAAEREMRIEGLRVIRKSGGKSGDFRQE
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: KPRS_METAC
Sequence: MKIIGGPASQLLASRTARALGTEPVLCEFNRFPDGELYLRIADEIENEKVTIIQSTPTDSDFVALLQLIDACEGAAEINVVIPYMGYARQDKKFKPGESISARAIARCINASRIFTINIHERSILDHFPCPAVNLDAASLVGEYIAGSGLENPMLVAPDEGAQGLVKNVAAGHGFDHDHLQKTRLSGDTVVIKTKNLDVTGRHVVLVDDMIATGGTMAESVRMLKAQGAIDVHLACVHPVLTRNAALRLFNAGVKDIIATDTLEKAESLLSVAPLIAEALKRL
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF184_ASFWA
Sequence: MKTFITCTSVKNYFRQHLKTNQRISSELISYVCTILNHICHQYLQNPQAQEEEWFALIKELPIIKDGLSKEERFFSSGVKHFLHEYKITPENQEKFQKMLNAITEQLMSRLCKVFSIMIQRQGFLKTQTLMYSHLFTILSILMVADNLYGEQDPTEFFSLIIEQTKTIKKKKKSSSEEEESHEE
What are the official names of this protein?
Uncharacterized protein E184L, pE184L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus E184L family.
What are the subcellular locations of this protein?
Virion.
Protein: HBB_CHRBR
Sequence: VHLTAEEKSLVSGLWGKVNVDEVGGEALGRLLIVYPWTQRFFDSFGDLSTPDAVMSNAKVKAHGKKVLNSFSDGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: IDI2_STAAR
Sequence: MSDFQREQRKNEHVEIAMAQSDAMHSDFDKMRFVHHSIPSINVNDIDLTSQTPDLTMTYPVYINAMTGGSEWTKNINEKLAVVARETGLAMAVGSTHAALRNPRMAETFTIARKMNPEGMIFSNVGADVPVEKALEAVELLEAQALQIHVNSPQELVMPEGNREFVTWLDNIASIVSRVSVPVIIKEVGFGMSKELMHDLQQIGVKYVDVSGKGGTNFVDIENERRANKDMDYLSSWGQSTVESLLETTAYQSEISVFASGGLRTPLDAIKSLALGAKATGMSRPFLNQVENNGIAHTVAYVESFIEHMKSIMTMLDAKNIDDLTQKQIVFSPEILSWIEQRSLNIHRG
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPYK_STAS1
Sequence: MRKTKIVCTIGPASESEEMLEKLIKAGMNVARLNFSHGDQAEHKARIDTIRKVSKRLGKTVAILLDTKGPEIRTHNMKDGLIELEKGSEVTVSMTEVEGTPEKFSVTYENLINDVEEGSYILLDDGLIELQVKSIDKANGEVLCDVLNTGELKNKKGVNLPGVKVSLPGITDKDADDINFGISEGVDFIAASFVRRPSDVLDIRKLLEAKQNKNISIIPKIENQEGIDNIKEILEVSDGLMVARGDMGVEIPPESVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGQYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGVSVAHTALNLNVKAIVAATESGSTARTISKYRPQSDIIAVTPNAETARQCALVWGIFPVVKEGRKTTDALLNNAVATAVETERVQNGDLIIITAGVPTGEKGTTNMMKLHLVGDELAKGQGIGRSSVVGKTLVVKDASELEGKDLSESIIVTSSVDETLVPYIENAIGLITEENGITSPSAIIGLEKGIPTVVGVENATSEIQSDVLITVDANQGKIFEGYANVL
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PEP-utilizing enzyme family.
Protein: MTAP_KORVE
Sequence: MQAEIGIIGGSGLYSMPGVSDVQEVRVTTPFGEPSDPYVLGTLAGRKVAFLARHGRGHRLLPTELNFRANIHGFKQLGVERIISVSAVGSLKEEHRPLEFVIPDQFYDRTKQRVSTFFGEGIVAHVGFGDPVCGEMAKVVKHATDKAGVVAKAGGTYVCMEGPQFSTKAESNLYRSWGFDVIGMTNLQEAKLAREAELCYVTVAMVTDYDCWHPDHDAVTVDQIVAVLLKNAENACSVVREAVAAMPKDRTCKCGSALATAIITNKDVVPAATKEKLKLIIGKYFGEQKAGA
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: CEFIP_HUMAN
Sequence: MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQSDFMPSLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQYCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS
What is the function of this protein?
Plays an important role in cardiomyocyte hypertrophy via activation of the calcineurin/NFAT signaling pathway.
What are the official names of this protein?
Cardiac-enriched FHL2-interacting protein.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line.
Protein: SYM_BIFLO
Sequence: MSHVLVNVAWPYANGPRHIGHVAGFGVPSDVYARYERMKGNDVLMVSGTDEHGTPILVEAEKEGLTAQELANRYNRVIAKDLCDLGLSYDLFTRTTTGNHEHVVQEMFKQCLENGYIYKGTQQVAISPSTGRTLPDRYIEGECPICHAEGARGDQCDACGNELDPDELINPVSKINGETPRFEQTEHYFLDLPALAEANKAWLETRKGWRTNVINFSLGLFKEVKPRAITRDIDWGIPVPVKGWIDNPNKKLYVWFDAVIGYLSASIEWARRQGDPEKWREWWNDPACPAYYFMGKDNITFHSQIWPSEMLAYNGKGSKGGETGPMGPLNLPEQVVASEFMTMEGKKFSSSRGIVIYVKDILARYPVDAVRYYISVAGPESSDSDFTWAEFVRHNNEELASSWGNLVNRVANLINKNFGEIPPLDEDSMTNEDRGLLEEASAAFDVVGSSIETHHQKHALSEAMRVVGDINKYISATEPWKIKDDQARLGTVLHVAAQAVSDANHLLAPFLPHSAQKVWEALGGTGTFSPLPELKEVEDLDKPGFTYPIITGDYELGVNVHPWKSEAIEVGAMVPKPAPIFAKIPTEAVEEELARFDEALAARRAAEAERLAAEKAKLAAE
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_HALH5
Sequence: MISVNDFKTGLTIEVDNGIWQVMEFQHVKPGKGAAFVRSKLRNLRTGAVQEKTFRAGEKVSKAHIENRRMQYLYASGDVHTFMDNETFEQLELSTAQIEHELKFLKENMEVHVISYQGETLGVEVPNTVELTVTETEPGIKGDTASGGTKPATLETGLTVQVPFFVNEGDVLVIDTRSGDYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.