PharMolix/UniProtQA huggingface dataset:
Protein: SURA_ALKEH
Sequence: MTAITRITLTGALLAAALLLAALQPARAETLDRIVAVVDDQVVLASELERELATIANQLRSRGQRLPPRDVFQRQVLERLITQRVQLSRAQRVGITVDDATLDAAMQRMARQNNMTLGQFRQAVEQEGFEYNYFREGIREEIAISRLRQAQVEEQVTVTPQEVEEVLETLDDENQEYRLGHILVATPEAASTAQLEEARERIEQLREQIIAGETDFEGAATAFSDAASAMEGGDLGWRLHSQLPSLFAEAIDEGLQAGEVSGVLQNSSGFHLVKLMDQRTQGGERVTETRARHILIRTDGDVITDEDARLRLRSLLERIEAGESFAELAEAYSEDPGSAARGGDLGWTQPGQLVPEFQGAMDALEEGQISAPFASPFGWHIVQVTDRRERDVSRERLRDQLAQQIHQRKVEEAFEQWIRRLRDEAYVDVRVEL
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: IF2_BURMA
Sequence: MASNNVAQFAAELKMPAGVLLEQLQAAGVQKASEDDALSETDKARLLDHLRKSHGATDGDKRKITLTRRHTSEIKQADATGKARTIQVEVRKKRTFVKRDDVSETGADQAQAQTDEQAEAELKRREEEARREAELLEKQAQELRERQERLEREEAERRAREEAAEAERRRAEEEAAAKRAAAAQAEAAQQAAAAREQAQRAQSEPAEQSAQDEARAAAERAAQREAAKKAEDAAREAADKARAEQEEIRKRREAAEAEARAIREMMNTPRRAQVKAVEPPKPAEPPAAKAAEAKGTLHKPAKPAGEAAAARPAAKKPASGAPAPAAAPAGDRTKKPGTGKSGWQDDAAKRRGIKTRGDSSGGVDRGWRGGPKGRGKHQDSASSFQAPTEPIVREVHVPETISVADLAHKMSIKASEVIKVMMKMGQMVTINQVLDQETAMIVVEELGHRALAAKLDDPEALLVEGEIGSDAEQLPRPPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETPRGVVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAISHAKAGGVPIVVAINKIDKPEANPDRVKQELVAEGVVPEEYGGDSPFVPVSAKTGAGIDDLLENVLLQAEVLELKAPVESPAKGIVIEAKLDKGKGPVATVLVQSGTLSRGDVVLAGTAYGRVRAMLDENGKPTKEAGPSIPVEIQGLSEVPGAGDEVIVLPDERKAREIALFRQGKFRDVKLAKQQAAKLESMLEQMGEGEVQNLPLIIKADVQGSQEALVQSLLKLSTDEVRVQIVHSAVGGISESDVNLATASKAVIIGFNTRADAQARKLAEANGIDIRYYNIIYDAVDEVKAAMSGMLAPEKREVVTGMVEVRQVFKVPKVGTVAGCMVTDGVVKRSSSVRVLRNNVVIFTGELDSLKRFKDDVKEVKQGFECGMSLKNFNDIVEGDQFEVFEVTEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_FRATM
Sequence: MSQFNQNNKQIDVMGIRKILPHRYPFALLDKIVDWSVEDRTIVAQKNVTINEDFFNGHFPDFPVMPGVLIVEAMAQATAILGELMAETLFAHVVEKAGGGRRTFMLAGIDKVRVKRPVVPGDVLVIESRMVKQKNIICTAESVAKVDGQIVCSAELMAAYKDY
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGP3_ARATH
Sequence: MAQLYSSVKPTPMLKDELDIVIPTIRNLDFLEMWRPFFEQYHLIIVQDGDPSKVINIPVGFDYELYNRNDINRILGPKASCISFKDSACRCFGYMVSKKKYIYTIDDDCFVAKDPTGKEINALEQHIKNLLSPSTPHFFNTLYDPYRDGADFVRGYPFSMREGAITAVSHGLWLNIPDYDAPTQLVKPLEKNSRYVDAVMTIPKGTLFPMCGMNLAFDRELIGPAMYFGLMGDGQPIGRYDDMWAGWCVKVICDHMGWGVKTGLPYIWHSKASNPFVNLKKEYNGIFWQEEAIPFFQSVTLPKECTSVQQCYLELAKLVREKLGKVDPYFITLATGMVTWIEAWEELNSAEGTEAEAPKGKN
What is the function of this protein?
UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides.  Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf).  Preferentially catalyzes the formation of UDP-Arap from UDP-Araf.  At thermodynamic equilibrium in vitro the ratio of the pyranose form over the furanose form is 95:5.  Is not active on other UDP-sugars (UDP-Gal, UDP-Xyl, UDP-Glc, GDP-Man and GDP-Fuc).  Is probably active as heteromer in vivo.
What are the official names of this protein?
UDP-arabinopyranose mutase 3, Reversibly glycosylated polypeptide 3, AtRGP3, UDP-L-arabinose mutase 3.
What is the protein family that this protein belongs to?
Belongs to the RGP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus. Note=Soluble and membrane-associated.
Protein: ATPG_SOLUE
Sequence: MPSLIDIRRRIRSVKNTQQITKAMKMVSAAKLRRAQDRTIAARPYGTLLRKVLGNVAAAVANDESAAENPLLARREERRILLVVITGDKGLAGAFNTNLIKAASRFVAEHSGEQITFELIGRKGRDYFRKREVAVSGEAIGLAAKVKYEDTAAIARRAMELFRNQEIDAVYLVYNEFKSVVSQKLTLSRVLPAELPEQANPVDYIFEEPPADMLNILLPKYVEMEFYRALLESAASEHAARMTAMDSATSNAAEMIDKLTLYMNRVRQASITKEIIEVVSGAAAAE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS4_ALCBS
Sequence: MARYIGPKCKLSRREGTDLFLKSGIRPLESKCKADQAPGQAAGASGRRPARLSDYGVQLREKQKVRRTYGVLEKQFRSYYKKAAASKGATGEVLLQLLEGRLDNVVYRMGFGSTRSEARQLVSHRAILVNGQSVNVASYQVKPGDQINVREKSKNQLRVKNAMELAQQRGFMPWIEVDDKKLEGTYKAKPERIDLPAEINENLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MPA5B_AMBPS
Sequence: MNNEKNVSFEFIGSTNEVDEIKVMACYAAGSICGEKRGYCSSDPGRYCPWQVVCYESRKICAKNAAKMRMNVTKNTI
What are the official names of this protein?
Pollen allergen Amb p 5b, Allergen Amb p Vb.
What are the subcellular locations of this protein?
Secreted.
Protein: LARMN_LACPL
Sequence: MHIPDNYLSPATCGTLVTAMAPVWTVAVLKVKVQIKKHHETLPMLGIAASLAFLIMMFNLPIPGGTTAHAVGGTLLAVLIGPWAACLALTVTLLLQALLFGDGGILAFGANALNMAVIMPFVGYACYRLGQKWHHEKLGLAIGAYLGINMAALVAGIELGLQPILAHTASGAPLYCPYGLNITIPAMLTAHLLVAGWVEVVFTLLVFQFVKRVAPTNLYQTPTRRNQRPWIALLLGLAVLSPLGLLASNTAWGEWSPQELQQRLAQQHISTHAPQGMVHGFHFQALFSDYAIAGLPVSVGYILSAITAVLIFLLLIRGLQHETDTSQH
What is the function of this protein?
Probably part of the energy-coupling factor (ECF) transporter complex LarMNQO involved in nickel import.
What are the official names of this protein?
Probable fused nickel transport protein LarMN, Probable energy-coupling factor transporter substrate-capture protein LarMN, ECF transporter S component LarMN.
What is the protein family that this protein belongs to?
Belongs to the CbiM family. NikM subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HCY6_HOMAM
Sequence: SPAFQAQKQAKVNDVLDKLY
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin subunit 6.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: QUEC_RHORT
Sequence: MPHSPTQRRAIVLVSGGLDSTTTLAIAQAEGFTVNALSFSYGQRHAVELEAARRVTQAFAVERHVIATIDLRQFGGSALTDSIGVPKQRSLETMGAGIPVTYVPARNTVFLSFALAWAEVLEANDVFIGVNALDYSGYPDCRPEYISAFQTMANLATKRGVEGTGVLTIHTPLIALTKGQIIRRGLDLGVDYALTHSCYDPSAEGEACGTCDSCLLRLKGFAENGLEDPVRYVGARSRAAG
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MUTH_PHOPR
Sequence: MQPTPKSESELLLRAQDLAGSTLGELAEQAGIITPPDLKRDKGWIGQLLEWHLGAMAGSKPIPDFPELGIELKTIPIGYSGKPLETTFVCVAPLIGLHGLHWGNSHIRHKLARVLWVPVEGERDIPLADRHVGSPLLWSPSIEEEQQLRQDWEELMDMIVLGRVEHITARHGEVLQLRPKAANSRALTEAYGANGQPIKTLPRGFYLKTHFTAAILARHFIL
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2_IPOPU
Sequence: MTKIYWNINLEEMMEAGVHFGHGTRKWNPKMAPYISAKRKGIHITNLTGTARFLSEACDLVFDAASRGKQFLIVGTKNKAADSVARASIRARCHYVNKKWLGGMLTNWSTTETRLHKFRDLRMEQKMGGLNRLPKRDATILKRQLARLQTYLGGMKYMTGLPDIAIIVDQHKEYTALQECITLGIPTICLIDTNCDPNLSDISIPANDDAISSIRFILNKLVFAICEGRSSYIINP
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EX3L2_HUMAN
Sequence: MAALENGELGPLLSPGTLRGLEDECVTDVKAQTRAALLRVLQEDEEHWGSLEDQPSSLAQDVCELLEEHTERAPRISQEFGERMAHCCLGGLAEFLQSFQQRVERFHENPAVREMLPDTYISKTIALVNCGPPLRALAERLARVGPPESEPAREASASALDHVTRLCHRVVANLLFQELQPHFNKLMRRKWLSSPEALDGIVGTLGAQALALRRMQDEPYQALVAELHRRALVEYVRPLLRGRLRCSSARTRSRVAGRLREDAAQLQRLFRRLESQASWLDAVVPHLAEVMQLEDTPSIQVEVGVLVRDYPDIRQKHVAALLDIRGLRNTAARQEILAVARDLELSEEGALSPPRDRAFFADIPVPRPSFCLSLPLFLGRLPLSRLARPSLACLPRPRPPSLARPRAQR
What are the official names of this protein?
Exocyst complex component 3-like protein 2, HBV X-transactivated gene 7 protein, HBV XAg-transactivated protein 7.
What is the protein family that this protein belongs to?
Belongs to the SEC6 family.
Protein: FGF1_RAT
Sequence: MAEGEITTFAALTERFNLPLGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESAGEVYIKGTETGQYLAMDTEGLLYGSQTPNEECLFLERLEENHYNTYTSKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
What is the function of this protein?
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.  Functions as potent mitogen in vitro.  Acts as a ligand for FGFR1 and integrins.  Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades.  Binds to integrin ITGAV:ITGB3.  Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling.  Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1.  Can induce angiogenesis.
What are the official names of this protein?
Fibroblast growth factor 1, FGF-1, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, HBGF-1.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as LRRC59 (By similarity).
Protein: SHSL1_HUMAN
Sequence: MTSCGQQSLNVLAVLFSLLFSAVLSAHFRVCEPYTDHKGRYHFGFHCPRLSDNKTFILCCHHNNTVFKYCCNETEFQAVMQANLTASSEGYMHNNYTALLGVWIYGFFVLMLLVLDLLYYSAMNYDICKVYLARWGIQGRWMKQDPRRWGNPARAPRPGQRAPQPQPPPGPLPQAPQAVHTLRGDAHSPPLMTFQSSSA
What are the official names of this protein?
Protein shisa-like-1.
What is the protein family that this protein belongs to?
Belongs to the shisa family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GPH_SYNE7
Sequence: MQAIIFDFDGTLVDSLPTVVAIANAHAPDFGYDPIDERDYAQLRQWSSRTIVRRAGLSPWQQARLLQRVQRQLGDCLPALQLFPGVADLLAQLRSRSLCLGILSSNSRQNIEAFLQRQGLRSLFSVVQAGTPILSKRRALSQLVAREGWQPAAVMYVGDETRDVEAARQVGLIAVAVTWGFNDRQSLVAACPDWLLETPSDLLQAVTQLMRQ
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: Y245_XANOR
Sequence: MTETSPTPVLDTAQARVLGCLIEKEATTPDAYPLTVNAAQVAANQKTAREPVLNLQTGVVHHALRQLENLGLVRQQFCSRAERYEHRLGSVLDLTRQQVALIGLLLRGPQTLGELYARSERLARFADTDDVRHHLDRLIQRGLAAQLPRASGQREDRYAHLLSGELDVEALQAATARAAQGARSGSDTSELEARVQSLEATVADMQDALAALQARLNAAGA
What are the official names of this protein?
UPF0502 protein XOO0245.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: TIMP4_RABIT
Sequence: ISSEKVVPASADPADTQRMIRYEIKQIKMFKGFEKIKDVQYIYTPFDSSLCGVKLEANSQKQYLLTGQVLSDGKVFIHLCNYIEPWEDLSLVQRESLNHHYHLNCVCQITTCYTVPCTISAPNECLWTDWLLERKLYGYQAQHYVCMKHADGTCSWYQGRLPLRKEFVDI
What is the function of this protein?
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
What are the official names of this protein?
Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4, TIMP-4.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SLB_ECHML
Sequence: MGRLISVRFSLLVVFLSLSGIGAGLCCPLGWSSFDQHCYKVFEPVKNWTEAEEICMQQHKGSRLASIHGSEEEAFVSKLASKALKFTSMWIGLNNPWKDCKWEWSDNARFDYKAWKRRPYCTVMVVKPDRIFWFTRGCEKSVSFVCKFLTDPAV
What is the function of this protein?
EMS16 is a potent and selective inhibitor of alpha-2/beta-1 (ITGA2/ITGB1) integrin and acts as a potent antagonist of platelet aggregation and cell migration.  Binds specifically to the I domain of the alpha-2 subunit, in a metal ion-independent fashion.
What are the official names of this protein?
Snaclec EMS16 subunit beta, EMS16B.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATG2_PICST
Sequence: MSPQWMPQNIQKRLLLYVLQQLSLFSEIDLPNLEEVSLNNIVLRDISIDPEKVGKLPGCNLRFGQVGTLELNTVTGGTIIGGGGGVNVDARDVEVVISPDFDINEEVRKEVQFSLAQSTADLAKTIIKDSDSAAEDESDDTDEEIVVEPKKSRSSSSSSFSGSTSKPSALSAVMSRAVEMALSRLQIKITNMKIKLVSEMTDLLFEVDEVLINTVNGTRVVKITGVRSMTLKPNVNPGELVEKVVQSPQKDDTSDNEEDDSNYEDDNNDYGDESLMDSMVFTHEEASSIYLSATSQSFPRPTSYNVDEGEVHVGNESVSSDPPAIFHMDYCDVEFDGLSNVSNLKIDIGTIKVATTPLAPTIISILNGITRSLKIKNHQKWTQQALKRQQNSRFPQYAETTDELTDDEASSKDGENTDPFFNKLHIRDIIISTTSALSRDGVFASPDNSINFVLHNSNIKQKNDMLIYGGVETFRIEQVKEGVTTDIFTFESPTAATHAEQSQSQPDSEGVSFAHGSPPPPIRPMSPSSISSMSSSGSKSSTLKADLRFEIFKKLEENVVTIETTALLSKTALLTLDLNSSLILSNFITAMNSIHSNFKVLMATIENLSKQQSPKKQKTHTNAAEAMTTKTQFILQTSPIIMSVKFTQDLLVKAIIFPISYNLQQNQLSISKILINTTIRNERESTTITISNIVLLTKLHEFKSFIKRIANPSNANPIPREVQVTASSNLFISKIMVNIALKELKFVISNIVSFYDSFASLSAKQSNSLENSVLDFVRDRSHKLEISSILQPPGQSRRRIGPGFASPHLSNPTFVNISRNNIASFRCSIKEVELNLVQVLPKFGGLTLRLKDILLYEQKNDINGSILSFDIVRVDDGQLQKFVYEFQELPLESIRLPLIMIHCKNTEKISTVDVVIRNVLVEYYTQWLLLLDDFEANEEKLAELVVEKVKPVNPSSSQNRFDIRFSVFDCIIGLNPGRLPCKSYLVVGRGTSDFTFGVNQFYIKSSFRDVSALLIDDVKNKEKMPLKDNSTSRSRKSLPTSSYTSPLTFFSNLGYIMIGGLNVVHIGITFNTNIEEVMKRNEKLGISDNLSLIDLKINSDEHHLELCADSTHVLLQLINDLKLPLNFKDDEKMKVTVDSSINLMDDLDENQFQLKKRNISVAPGVETSSSSAGSENENLETIAFDEDHFSKARNKIPKGSKVDPFKLNINLSKTKIYLYDGYDWKDTRKAVRGAVKRVEAQAMKERLKKLKKQTDKDDYDEEDEFIEETLFSSIHVGIPRDATDANLTDRINKRVQSSLQETDMTPEEAQKAQINVELGKNYKNLKLRRSRVHKIMADFTNIEVNVSVYSTRDPRKDPTDENLPYELLNDVEVRLGTADVYDNVATSTWNKLLTYMNTSGEGEIGKSMLKLAITNVRPSPKLVSSEAIMKVQVLPVRLHIDQDTLDFLMRFLEFKDSRFSLPLDEIVYIQKFQISPVMLKLDYKPKRVDYVGIRSGNSAEFMNFFILDGSTINLAEATVYGLLGMPSLGKALGEVWGPQIQQTQIAGILAGLAPIRSIVNIGGGVKDLIAIPISEYKKDGRLFRSIQKGTQKFAKTTGYEILNLGVKLASGTQVILEQGEQLLGGEGSGARLPASRGSNSQKCNVNKRSSYKVAAKVDFNKLLANSQVLNQSVRVDRDQYANKKFYSYIDIDEDDDELVTGIDKELLSKSIFLLPRDDNSKKEGEEDEADDSSADEEGEKLISLYSNQPENIQEGMKLAYKSFGNNLKITKRQLINLKNELNESENIQDSLKSILKSSPIIFIRPIIGSTEALSKALMGLGNEIDSKRIVESRDKYRYIKRAKDEDVL
What is the function of this protein?
Lipid transfer protein required for autophagosome completion and peroxisome degradation.  Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion.  ATG2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region.  The latter binding is assisted by an ATG18-PtdIns3P interaction.  ATG2 then extracts phospholipids from the membrane source using its NR and transfers them to ATG9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
What are the official names of this protein?
Autophagy-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATG2 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: CHSB_IPOTR
Sequence: MSTTVTVLTDTWGRRAKRFEIEGYAKILAIGTATPANWVDQTTYPDFYFRITNSQHLLEHKEKFRRICNKSKIRKRHLVLTEELLQKNPSLCTYNETSLNTRQDILVSEVPKLGKEAAMKAIKEWGRPISEITHLVFCTTSGVDMPGADFRLTKLLGLNSSVKRLMMYQQGCNAGAAMLRLAKDLAESNKGGRILVVCSEITINIFRGPSLEQDDNLLAQCLFGDGSAAMIVGTDPRPDLETPLFELVSSAQTIVPNTDSHLKLTLREMGLTFHCSRAVPSVLAENVEDCLVKAFEPYGISDWNSIFWVFHPGGNAIVDRVEERLGLGAQRFRASRDVLSEYGNLTSACVLFILDEVRNKSKKNEQ
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase B, Naringenin-chalcone synthase B, CHS-B.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: DAPDH_CORGL
Sequence: MTNIRVAIVGYGNLGRSVEKLIAKQPDMDLVGIFSRRATLDTKTPVFDVADVDKHADDVDVLFLCMGSATDIPEQAPKFAQFACTVDTYDNHRDIPRHRQVMNEAATAAGNVALVSTGWDPGMFSINRVYAAAVLAEHQQHTFWGPGLSQGHSDALRRIPGVQKAVQYTLPSEDALEKARRGEAGDLTGKQTHKRQCFVVADAADHERIENDIRTMPDYFVGYEVEVNFIDEATFDSEHTGMPHGGHVITTGDTGGFNHTVEYILKLDRNPDFTASSQIAFGRAAHRMKQQGQSGAFTVLEVAPYLLSPENLDDLIARDV
What is the function of this protein?
Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.  Probably plays a role in lysine biosynthesis.  Exhibits a high substrate specificity for meso-2,6-diaminopimelate, since L,L-2,6-diaminopimelate, D,D-2,6-diaminopimelate, L-glutamate, L-alanine, L-leucine, L-valine, L-aspartate, L-threonine, L-homoserine, L-methionine, L-lysine, L-serine, L-phenylalanine, L-tyrosine, L-tryptophan, L-ornithine, L-histidine, L-arginine, D-glutamate, and D-alanine are not substrates for the oxidative deamination reaction.  Can use NAD(+) only poorly since the activity observed in the presence of NAD(+) is about 3% of that with NADP(+).
What are the official names of this protein?
Meso-diaminopimelate D-dehydrogenase, DAPDH, Meso-DAP dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate dehydrogenase family.
Protein: COX6C_BOVIN
Sequence: MSTALAKPQMRGLLARRLRFHIVGAFMVSLGFATFYKFAVAEKRKKAYADFYRNYDSMKDFEEMRKAGIFQSAK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6C, Cytochrome c oxidase polypeptide VIc, Cytochrome c oxidase subunit STA.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6c family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ATPE_CYAPA
Sequence: MSLDVRVIAPNKVIWAKNAEEVILPSQSGMLGILTSHAPLYTALNTGVMKIRNETGWTSIVVMGGFVEVEKNEVLVLVNAGEYVDEIDLSAAKKDVEKALETFNSAEAPKEKEEAAEFLKYAQARLKAVVDK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, cyanelle, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, cyanelle thylakoid membrane; Peripheral membrane protein.