PharMolix/UniProtQA huggingface dataset:
Protein: Y1082_PSEE4
Sequence: MVDSYDDAFDGEKSKTQIKRELHALVELGERLTTLKADTLARLPLTDELRKALDEASRHTAHGARKRHMSFVGKLMRVQDLDAIHAVLEQIDSSSRQYNERFHGLERWRDRLIDGNDEDLERFVNEFPDTDRQHLRSLIRHAQHEKARNKPPAAARKVFKYIRDLDETQRGLR
What are the official names of this protein?
UPF0307 protein PSEEN1082.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: RS7_ACIF5
Sequence: MPRRREVPKRVVLPDPKYKEEVIAKFANVMMRDGKKSTAEKIVYGALEMVAERSKSDALEIFRKAIDNVRPVVEVKSRRVGGATYQVPVEIRSDRRMALAMRWLRDSARKRNEKSMGNRLAAEILEAAENRGNAVRKREETHRMAEANKAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ATPF_GOSHI
Sequence: MKNVTDSFVSLGHWPSAGSFGVNTDILATNPINLSVVLGVLIFFGKGVLSDLLDNRKERILNTIRNSEELRGGAIERLEKARARLRKVEMEADQFRVNGYSEIEREKLNLINSTYKILEQLENYKNETIYFEQQRAINQVRQRVFQQALQGALGTLNSSLNNELHLRTISANIGLFGVMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CITG_ECOLI
Sequence: MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNNSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
What is the function of this protein?
Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA.
What are the official names of this protein?
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: NBP22_DROYA
Sequence: MLEKVKNIIVVLSGKGGVGKSTVSTQLSLALRKNGFKVGLLDIDLCGPSVPYLLGLEGRDIFQCDEGWVPVYTDESQTLAVMSIGFLLKNREDPVIWRGPKKTMMIRQFLTDVRWDELDYLIIDTPPGTSDEHITVMECLKEVGCHGAIIVTTPQEVALDDVRKEITFCKKTSINILGIVENMSGFVCPHCTSCTNIFSSNGGTSLANYAQVPHLGTLPIDPRVGVLAGSTTSVLDELPDSTTAEVLTHIVEKLKTIFVS
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5EAS1_NICAT
Sequence: MASAAVGNYEEEIVRPVADFSPSLWGDHFLSFSIDNQVAEKYAQEIEPLKEQTRSMLLATGRKLADTLNLIDTIERLGISYYFEKEIDEILDHIYNQNSNCNDFCTSALQFRLLRQHGFNISPQIFSKFQDENGKFRESLASDVLGLLNLYEASHVRTHADDILEDALAFSTIHLESAAPHLKSPLREQVTHALEQCLHKGVPRVETRFFISSIYEKEQSKNNVLLRFAKLDFNLLQMLHKQELAEVSRWWKDLDFVTTLPYARDRVVECYFWALGVYFEPQYSQARVMLVKTISMISIVDDTFDAYGTVKELEAYTDAIQRWDINEIDRLPHYMKISYKAILDLYKDYEKELSSAEKSHIVCHAIERMKEVVGHYNVESTWFIEGYMPPVSEYLSNALATTTYYYLATTSYLGMKSATEQDFEWLSKNPKILEASVIICRVIDDTATYEVEKSRGQIATGIECCMRDYGISTKKAMAKFQKMAETAWKDINEGLLRPTPVSTEFLTLILNLARIVEVTYIHNLDGYTHPEKVLKPHIINLLVDSIKI
What is the function of this protein?
Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol.  Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.
What are the official names of this protein?
5-epi-aristolochene synthase 1, NaEAS34.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA1_TORMA
Sequence: VLSEGNKKAIKNLLQKIHSQTEVLGAEALARLFECHPQTKSYFPKFSGFSANDKRVKHHGALVLKALVDTNKHLDDLPHHLNKLAEKHGKGLLVDPHNFKLFSDCIAVTLAAHLQEFSPETHCAVDKFLEEVTYQLSSLYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1, Alpha-1-globin, Hemoglobin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MRAZ_TREPA
Sequence: MEDNAFTGAYSYNLDEKGRLMLPARLRVALSDTRLVLTCAIESCLWVFPRAQWDRFSSQISARASLFHAPSRAVLRRLIAPAQEVELDRAWRLFIPPSLREYAALEKDCLILGLSHCLEIWDRARYRAYLAESEADFRAGTETLQDLCL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CCR1_MAIZE
Sequence: MDPKATSTSKTDNIDQITIIEEKVNKIGTEPTIRKYSKGRMLGKGGFAKCYEVTNLENKKVLAGKIICKASLTKSRAKQKLISEIKIHKSLRHSNIVEFEHVFEDQENVYILLELCPNQSLHDLIKRRKRLTEIEVQCYTLQLICGLKYLHSRRVIHRDLKLGNLLLNDKMELKICDFGLAAKLEFDGEKRKTVCGTPNYIAPEVIEGKGGHSYEVDTWSLGVIIYTLLVGRPPFETSDVKQTYKRIKACEYSFPDHVSVSDTAKNLVQKMLTLDPSKRPSLDEILQHPFLKNANNIPKFLPASTLACPPSTSYLNQFASPENSVKVPSQPAPKSAEATPLAAQKNGRFINTQGSNMFGSEKTLVTSPHSATTQAHTNENVVLTSQLDRHQTQGEKGWNFTKTGSWQSNLNGTQSVKGSSRPQTVQQKGDLKSAQSLKAPALLNNLGSRLRVSGSAVGSNRGQVLSGNEVWVKKWVDYSSKYGMGYNLSNGTTGVFFNDNTKIVFNQKTDQVTYIQRGKNDRQDTVTHYSLTEYPKDLQKKMTLLQHFKKYLEGSEYGGSESINDGTETQIGVYVKKWVKTKNATLFRLSNKTVQVHFTDRTEIILNSENKQVTYVARKETEPISP
What is the function of this protein?
May play a role in the division of some cell types.
What are the official names of this protein?
Probable serine/threonine-protein kinase CCRP1, Cell-cycle related Protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
Protein: IF2G_META3
Sequence: MVKVKQSEINIGMVGHVDHGKTSLTRQLTGTWTDTHSEELKRGISIRLGYADCEIMKCPKCGAPEAYSVSKTCPVCGTKTKMSRKISFVDAPGHETLMATMLSGASLMNGAILVIAATEKCPQPQTKEHLMALDALGIENIIIVQNKIDLVDEERAKESYNEIKEFVKDTVAEKAPIIPISAHHGANIDILLNAIEDLMPTPEMDEGAPARLYVARSFDINKPGCEISKLKGGVIGGSIIQGTLNSGEKIEIKPGLKIVEGNKIRWESIITKITSLGVGGKTVKVAHPGGLVGIGTELDPALTKSDSLSGCVAGAPGTLPETLSEITVQTKLLDRIVGSDEELIISPLKSNEALMLNVGTATTVGIITSARGDMADMKLKLPICADKGDRIAMSRRIGSRWRLIGYGIIQ
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit gamma, aIF2-gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: N7BM_YARLI
Sequence: MSSSLYRVLRNAWEVGPRSYWKQLNSIGDTKSGRLVGTDIYGNKFYETDHQDEIHLRTRYVEYKEKDYDMSQVEPGWHFWLGYGVDTAPCNTPKEKLPIRAYPYKFQPNYTGTPGAFVTYNTLKPKISAWEPVTKQRS
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit N7BM, NADH-ubiquinone oxidoreductase subunit N7BM.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA12 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RLR76_PLAVT
Sequence: MSGAFYVFTALLLVASDQIAAESGKRLEMYKHDVMAASNAVVKSLPNRFLRGSRDEPDNLANEERTVYSVLASMINEGVSKMPCAAEVVEKISHTTEAVENMPRAAKAVKKRPRGAKAGRKMPRAAEAEAVKKVPRAGTAVKKAPPLAEDVKEMPRAKEAMEELRRAADATEDMQRAKANDLLKALIGADEALKKHWTPSGNTAAIGDTSYDVFNKVILSLPEWKINFRGMKSMAVLDQHRENIDLVHKTFEILCDKNVKPTAAEVSFIWSMMEWKGPNPEKYHRRNLVRQAQRYVFLDLRNVKKR
What is the function of this protein?
Secreted effector that partially suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 76.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=Localizes to bulk/chunk- like structures within the nucleus.
Protein: PTH_CLOD6
Sequence: MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKALIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRIRKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINEALEKAADAIDSIIRENIDMSMNKYNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMP1_EBVG
Sequence: MERDLERGPPGPPRPPLGPPLSSSIGLALLLLLLALLFWLYIVLSNWTGGALLVLYSFALMLIIIILIIFIFRRDLLCPLGGLGLLLLMVTLLLIALWNLHGQALYLGIVLFIFGCLLVLGLWIYFLEILWRLGATIWQLLAFILAFFLAIILLIIALYLQQNWWTLLVDLLWLLLFMAILIWMYFHGPRHTDEHHHDDSLPHPQQATDDSSHESDSNSNEGRHHLLVSGAGDGPPLCSQNLGAPGGGPDNGPQDPDNTDDNGPQDPDNTDDNGNTDDNGPQDPDNTDDNGPHDPLPHNPSDSAGNDGGPPNLTEEVENKGGDRGPPSMTDGGGGDPHLPTLLLGTSGSGGDDDDPHGPVQLSYYD
What is the function of this protein?
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation.  Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family.  LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells.  Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins.  For example, induces the sumoylation of host IRF7 thereby limiting its transcriptional activity and modulating the activation of innate immune responses.  Inhibits also host IFN-alpha-stimulated STAT2 nuclear translocation and interferon-stimulated response element transcriptional activity by interacting with and inhibiting host TYK2.  Induces SUMO expression during viral latency thereby dysregulating the host sumoylation processes.
What are the official names of this protein?
Latent membrane protein 1, LMP-1, Protein p63.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae LMP-1 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein.
Protein: RM38_PONAB
Sequence: MAAPWWRAALCGCRRWRGFSTSAVLGRRTPPLGPMPNSDIDLSNLERLEKYRSFDRYRRRAEQEAQAPHWWRTYREHFGEKTDPEEKIDIGLPPPKVSRTQQLLERKQAIRELRANVEEERAARLRTASVPLDAVRAEWERTCGPYHKQRLAEYYGLYRDLFHGATFVPRVPLHVAYAVGEDDLMPVYCGNEVTPTEAAQVPEVTYEAEEGSLWTLLLTSLDGHLLEPDAEYLHWLLTNIPGNRVAEGQVTCPYLPPFPARGSGIHRLAFLLFKQDQPIDFSEDARPSPCYQLAQRTFRTFDFYKKYQEAMTPAGLSFFQCRWDDSVTYIFHQLLDMREPVFEFVRPPPYHPKQKRFPHRQPLRYLDRYRDSHEPTYGIY
What are the official names of this protein?
39S ribosomal protein L38, mitochondrial, L38mt, MRP-L38.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL33_NEIG1
Sequence: MRDKIKLESGAGTGHFYTTTKNKRTMPGKLEIKKFDPVARKHVVYKETKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL7_ECO57
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12, L8.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TINAG_HUMAN
Sequence: MWTGYKILIFSYLTTEIWMEKQYLSQREVDLEAYFTRNHTVLQGTRFKRAIFQGQYCRNFGCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYPEGCFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVCLVRSELIEQVNKGDYGWTAQNYSQFWGMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWYLRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAAWGQLTSSDEP
What is the function of this protein?
Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3.  This is a non catalytic peptidase C1 family protein.
What are the official names of this protein?
Tubulointerstitial nephritis antigen, TIN-Ag.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: DNAA_CHLTE
Sequence: MSDTIQQEAPDNLQVTPTHGRSFAEKVWSACLGLIQENINTLAFKTWFLPIRPLSFSGSELTIEVPSQFFYEWIEENYSVHVKQALRQVIGPEAKLMYSIVIDKSQGQPVTIELPHQIDAAPAERSVRPEAPGQKASAERERLEIARPRFESNLNPKYTFSTLVRGDCNSLAFAASKSIAQNPGQNAFNPLVIYGGVGLGKTHMMQAIGNSVLENRITDAVLYVSSEKFAIDFVNAIQNGNIQEFSAFYRNIDVLIIDDIQFFAGKEKTQEEIFHIFNTLHQSNKQIILSADRPIKEIKGIEDRLISRFNWGLSTDIQAPDYETRKAIIQSKLKQSGVSLDPVVIEFIATNVTSNVRELEGCIVKLLAAHSLDNQEIDLQFAKSTLKDIIRYNTKQLTLETIEKAVCSYFSITSNDLKGKSKKKEIAVGRQIAMYLSKDMTDSSLKTIGLHFGGRDHSTVIHALNTIEKKIAASNEERKKIEELRKRIEIMSM
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNJ2_BACSU
Sequence: MKKKNTENVRIIALGGVGEIGKNLYVIEIDSDIFVVDAGLMHPENEMLGIDVVIPDISYLIERADRVKAIFLTHGHDENIGGVFYLLNKLSVPVYGTKLTLALLREKLKQYGHNRKTDLREIHSKSVITFESTKVSFFRTIHSIPDSVGVSFKTSLGSIVCTGDFKFDQTPALNQTCDIGEIAKIGNSGVLALLSDSANAERPGYTPSEAAVSGEISDALYNSQNRVIIAVFASNINRIQQVIHAAAQNGRKIAVAGKNLQSVLQLARKLGYIEADDELFISVQDVKKYPKREVAIITAGSQGEPLAALTRMANKAHKQLNIEEGDTVVIASTPIPGQELIYSKTVDLLARAGAQVIFAQKRVHVSGHGSQEELKLMINLLKPKYLIPVNGEYRMQKAHSKIAEETGMKRSDIFLIEKGDVVEFRGQNVKIGDKVPYGNILIDGLGVGDIGNIVLRDRRLLSQDGILIVVITLDKQKKHLVSGPEIITRGFVYVRESEGLIVQATELVRSIVTEATETSNVEWSTLKQAMRDALNQFLYEKTKRKPMIIPIIMEV
What is the function of this protein?
Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs.  Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone.  The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides, on shorter substrates is distributive.  Plays a role in mRNA maturation and stability.  Appears to have a limited effect on 16S rRNA maturation, despite its similarity to RNase J1.  This subunit alone has very poor 5'-3' exonuclease activity.
What are the official names of this protein?
Ribonuclease J2, RNase J2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_SYNY3
Sequence: MGSIRLMHAKLHRVCVTEANVNYVGSITIDPVMLERVGLLPLEEVDIINLSNGNRFSTYVLPGQAHSKEICPNGGAALLCQPGDRLIIFAYELCDRREVLQKGHQAKVLVTNESNETVDFYLQELIPKEDGVKFINNICSEAIPH
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_BRUC2
Sequence: MGLTGTNTTLVAPQPKGILDPRTGKPVGSDDAFFNDLNGELSDKGFIVTSADALITWARTGSLMWMTFGLACCAVEMMHISMPRYDAERFGIAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRVVPVDIYVPGCPPTAEALLYGILLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BETB_BRUC2
Sequence: MKAQPKASHFIGGAFVEDKAGKPLPVIYPATDEEIASLYSATPGIIEAAYAAALKAQGEWAALKPVERGRILRRTAEILREKNRKLSKLETLDTGKALQETLVADAASAADALEFFGGIISGFNGEFVELGGSFAYTRREALGICVGIGAWNYPIQIAAWKSAPALAMGNAFIFKPSENTPLSALALAEAYKEAGLPDGLFNVVQGYGDVGAALVNHRLTAKVSLTGSVPTGRRIMAQAGEQLKHVTMELGGKSPLIVFDDADLESAIGGAMLGNFYSTGQVCSNGTRVFVHKNIRERFIERLVERTRKIRIGDPFDEATQMGPLISAAQRDKVLSYIKKGKAEGATLACGGGVPKLQGFDKGFFIEPTVFADVTDTMTIAREEIFGPVMSVLEFSDEDEVIARANDSEFGLAAGVFTADLSRGHHVIGQIKAGTCWINAYNLTPVEVPFGGYKQSGIGRENGIAALAHYSQIKTVYVEMGKVDSPY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: PKHH3_HUMAN
Sequence: MPLPGGLWWLLCCRRGFTLLHRDYGDGELSGDGDEDEDEETFELRTPSPAGGGRGPLEVTLTQPVRSGPVSNRLQSWEETWSLIPEKGLPEDDPDIVVKGWLYREPRGGGARPWLPPRRAWFVLTRDSLDQFSSSGKGARRLGSLVLTSLCSVTGPERRRKETGLWSVTVSGRKHSVRLCSPRQAEAERWGVALREVIASKAPLETPTQLLLRDIQESCGDPEAVALIYLRNPILRHTSGALYAPLLPLPYGVSAPGPGYAPLREEAVRLFLALQALEGARRPGPLMQGVLQTCRDLPALRDELFLQLAKQTSGPAGPPGLPATQDPAALRYWQLLTCMSCTFRPGGAVRGHLLGHLERTEQALPDSELAEYARFIRKALGRTRGRELVPSLAEISALSQRQELLCTVHCPGAGACAVAIDSHTTAGEVARELVGRLGLARSRNAFALYEQRGAQERALAGGTLVADVLTRFENLAAEEAGLEDSPDSGWRLCLRLHGPLHPEGLSPDGHELPFLFEQAHALLLRGRPPPPDDTLRALAALRLQSLQRDFSPRVPLPRLDRLLPPPAPPREDPPRPTPRPPPSAALLAGALWSPGLAKRRAERARRGGAGRTAGSIAREGGGGAGTAAAVLGGWKRLRGMGRAEAMAAYLALAAQCPGFGAARYDVLELSTEPGRGAPQKLCLGLGAKAMSLSRPGETEPIHSVSYGHVAACQLMGPHTLALRVGESQLLLQSPQVEEIMQLVNAYLANPSPERPCSSSSPPCQDLPDTSPPSQRPGLDEPQGQSGCLGQLQD
What are the official names of this protein?
Pleckstrin homology domain-containing family H member 3, PH domain-containing family H member 3.
Protein: SYE_SALA4
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARHHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLNLEWDEGPYFQTKRFDRYNAVIDEMLEAGTAYKCYCSKERLEQLREDQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQDGSVIFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALNAPVPMYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSSGDQEIFTREEMIKLFSLGAVSKSASAFNTDKLLWLNHHYINTLAPEYVATHLQWHIEQENIDTRNGPQLAELVKLLGERCKTLKEMAQSCRYFYEDFSEFDADAAKKHLRPVARQPLEVVRDKLSAITDWSAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALGFIAERESQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETFB_HUMAN
Sequence: MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI
What is the function of this protein?
Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase (PubMed:25416781, PubMed:15159392, PubMed:15975918).  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable).  Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism (PubMed:12815589, PubMed:7912128).  ETFB binds an AMP molecule that probably has a purely structural role (PubMed:8962055, PubMed:15159392, PubMed:15975918).
What are the official names of this protein?
Electron transfer flavoprotein subunit beta, Beta-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SECB_PHEZH
Sequence: MSETDAGAPGAPEAAEGQAPGIRILAQFIRDLSFENPRAPDALRAAQTQPQIDLGVEMNARGREDGLFEVDLKLSARATRDDGALFVVELLYGGVFQIAGVPAEDLEPVLLIECPRYLFPFARRIIADVTAEGGFPPFMLDPIDFAGVYAARKAQEQEQVGHA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCKXH_DROME
Sequence: MWNMGLLFLIYYCVSIYSAKGDTKDGQVLPLDVGALAEDAGDAEANGEDTPERNSESSVLDTTLAFEPQASTQSTPIHGAVPTWRPKRDNCTPPAIEQFPQPLMNKWARQHGGLILHILVAVFTFFGLAIVCDEYFVASLDRLCEELKLSPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISVCALCSGTVCQLNWWPLVRDCFFYCVSILVMLIIIFNDVISCFESVVMLLCYVGYCVALHFNTELERWALGLNLPFKLPSKEEQSALVTYKNVPEGSYTQESVGQTQGQKATDDSETRSAKPQSDYQDYSDPNPTWDPNAAWGDESQPNPVANPPPVDDWGMGHSGQENMGYHADQPESVVTGDGPPAAVKSGGQVVSTQATSAGGNDYYKSTDKQREPRRDPLLRPMEGGLPALVSWYVVYPIHFLCKKTMPDCRQEQYRNWYPFTFLMSMVWISFYSYFMVWMITVIGSTLAIPDTVMGLTFVAAGVSVPDALSSIAVIKEGFGDMAVSNAIGSNVFDILVCLGLPWFIQTAIIKPGSHVNVISKGLAYSTLSLFSTVVFLILSTHLNGWKLDKRLGIILMVWYLFFITLASLYELNVFGYMNPPECPSTY
What is the function of this protein?
May function in the removal and maintenance of calcium homeostasis.  Transports one Ca(2+) and 1 K(+) in exchange for 4 Na(+) (By similarity).
What are the official names of this protein?
Probable sodium/potassium/calcium exchanger CG1090, Na(+)/K(+)/Ca(2+)-exchange protein CG1090.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.