PharMolix/UniProtQA huggingface dataset:
Protein: SAR1B_BOVIN
Sequence: MSFIFDWIYSGFSSVLQFLGLYKKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETVANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGNVSLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID
What is the function of this protein?
GTP-binding protein involved in transport from the endoplasmic reticulum to the Golgi apparatus.  Activated by the guanine nucleotide exchange factor PREB.  Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity).  Synergizes with the cargo receptor SURF4 to mediate the export of lipoproteins from the endoplasmic reticulum, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis (By similarity).
What are the official names of this protein?
GTP-binding protein SAR1b.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.
Protein: Y686_STRZJ
Sequence: MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVPTQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR
What are the official names of this protein?
UPF0298 protein SPJ_0686.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJCG_BACSU
Sequence: MKYGIVLFPSKKLQDLANSYRKRYDPSYSLIPPHLTLRASFECAEEKADQLVSHLRNIAKESHPLVLKMTKYSSFAPVNNVIYIKAEPTEELKTLNEKLYTGVLAGEQEYNFVPHVTVGQNLSDDEHSDVLGQLKMQEVSHEEIVDRFHLLYQLENGSWTVYETFLLGRGE
What are the official names of this protein?
Putative phosphoesterase YjcG.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: YPEA_ECOL6
Sequence: MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSLFLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPKIQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY
What are the official names of this protein?
Acetyltransferase YpeA.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. YpeA subfamily.
Protein: LEPA_NEIG1
Sequence: MKNIRNFSIIAHIDHGKSTLADRFIQYCGGLDLREMSTQVLDSMDIEKERGITIKAQTAALNYKARDGQVYQLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTAIDLGVEVVPVLNKIDLPAADPERVEQEIEDIIGIDAVGAVQCSAKSGIGVEDVLEEIVAKIPAPTGDENAPLQAVIVDSWFDNYVGVVMLIRVKNGTIKLKDKVRFMSTKAETQVEQLGVFTPKSVQKQELKAGEVGFLITGVKELGQAKVGDTVTLVANPATEPLPGFQEVQSQVFAGLYPVESHDYEALRDALEKLQLNDASLKFEPEVSQALGFGFRCGFLGLLHLEIVQERLEREFDMDLITTAPTVVYEVVLKSGEKIEVENPSKLPDIGSIETILEPIITATILVPQEYVGNVMTLCNQKRGVQVNMQYMGRQVMLTYDLPMNEVVMDFFDKLKSTSRGYASLDYHFKEFQPSDLIKLDIMVNGEKVDALSLIVHRQSAVHKGRELASKMRELIPRQMFDIAVQAAIGSRIIARENVKALRKNVLAKCYGGDITRKKKLLEKQKAGKRRMKQVGNVEIPQSAFLAILQVSDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MGRB_ECOLI
Sequence: MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
What is the function of this protein?
Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.  PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol).  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway; the 2 periplasmic Cys residues of MgrB are required for its action on PhoQ, and thus PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: COAD_CARHZ
Sequence: MRIAVYPGSFDPITNGHLDIIERAAELFDRLIVAIAKNPMKKPLFTLEERLDMLRETLKYYPNIEIDSFEGLTVNYLKAKNAQVIIRGLRAISDFENEFMMALTNKKLVPWVETIFLMTKAEYSFISSSAVKEVAMYGGCLKGLVPEYVELKLREKFQKEGC
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_MYCTA
Sequence: MGAIMLDGKATRDEIFGDLKQRVAALDAAGRTPGLGTILVGDDPGSQAYVRGKHADCAKVGITSIRRDLPADISTATLNETIDELNANPDCTGYIVQLPLPKHLDENAALERVDPAKDADGLHPTNLGRLVLGTPAPLPCTPRGIVHLLRRYDISIAGAHVVVIGRGVTVGRPLGLLLTRRSENATVTLCHTGTRDLPALTRQADIVVAAVGVAHLLTADMVRPGAAVIDVGVSRTDDGLVGDVHPDVWELAGHVSPNPGGVGPLTRAFLLTNVVELAERR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: LIPB_PSECP
Sequence: MTLEFSGLGLAPEFVDYQHAWDVQRELHGKVVAGEAPSTVLLLEHAAVYTAGKLTEDHERPFDGTPVVAVDRGGKLTWHGPGQLIAYPILKLKNRAGIRDYVERLEAVMIAVMADYGIRAERIKGRAGVWVKADANGPDRKIAAIGIRVLNGVTMHGVAINCSNDLAPYGQIIACGITDAGVTTMSRETGKDIRPADIAERFVEEFRKHEEALVSSPEGALL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_FRATM
Sequence: MKKILNKYSRRLTEDKSQGASQAMLYGTGMNDADMHKPQIGIGSVWYEGNTCNMHLNQLAQFVKDSVEKENLKGMRFNTIGVSDGISMGTDDMSYSLQSRDLIADSIETVMSAHWYDGLVSIPGCDKNMPGCMMALGRLNRPGFVIYGGTIQAGVMRGKPIDIVTAFQSYGACLSGQITEQERQETIKKACPGAGACGGMYTANTMACAIEALGMSLPFSSSTPATSVEKVQECDKAGETIKNLLELDIKPRDIMTRKAFENAMVLITVMGGSTNAVLHLLAMASSVDVDLSIDDFQEIANKTPVLADFKPSGKYVMANLHAIGGTPAVMKMLLKAGMLHGDCLTVTGKTLAENLENVADLPEDNTIIHKLDNPIKKTGHLQILKGNVAPEGSVAKITGKEGEIFEGVANVFDSEEEMVAAVETGKVKKGDVIVIRYEGPKGGPGMPEMLKPTSLIMGAGLGQDVALITDGRFSGGSHGFIVGHITPEAYEGGMIALLENGDKITIDAINNVINVDLSDQEIAQRKSKWRASKQKASRGTLKKYIKTVSSASKGCVTDLD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RNJ2_STAA3
Sequence: MSLIKKKNKDIRIIPLGGVGEIAKNMYIVEVDDEMFMLDAGLMFPEDEMLGIDIVIPDISYVLENKDKLKGIFLTHGHEHAIGAVSYVLEQLDAPVYGSKLTIALIKENMKARNIDKKVRYYTVNNDSIMRFKNVNISFFNTTHSIPDSLGVCIHTSYGAIVYTGEFKFDQSLHGHYAPDIKRMAEIGEEGVFVLISDSTEAEKPGYNTPENVIEHHMYDAFAKVRGRLIVSCYASNFIRIQQVLNIASKLNRKVSFLGRSLESSFNIARKMGYFDIPKDLLIPITEVDNYPKNEVIIIATGMQGEPVEALSQMAQHKHKIMNIEEGDSVFLAITASANMEVIIANTLNELVRAGAHIIPNNKKIHASSHGCMEELKMMINIMKPEYFIPVQGEFKMQIAHAKLAAEAGVAPEKIFLVEKGDVINYNGKDMILNEKVNSGNILIDGIGIGDVGNIVLRDRHLLAEDGIFIAVVTLDPKNRRIAAGPEIQSRGFVYVRESEDLLREAEEKVREIVEAGLQEKRIEWSEIKQNMRDQISKLLFESTKRRPMIIPVISEI
What is the function of this protein?
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity.  Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J 2, RNase J2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOMY_BACSU
Sequence: MSTIKVKSAHKDGQIKLEDLDVVCNKLCKRNNSVLFKLEKYLNKKLLSDPELTEIRDTILTVSGELSRLRDNLVTDGDSNEGLQ
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YomY.
Protein: TSAD_STACT
Sequence: MSKDTLILAIESSCDETSASVIKNGKEILSNTVLSQIESHKRFGGVVPEVASRHHVEGITTTIEEALNTADTSMEEIDAVAVTEGPGLIGALLIGINAAKALAFAYDKPLVPVHHIAGHIYANNLEEPFEFPLMALIVSGGHTELVYMKDHLSFEVIGETRDDAVGEAYDKVARTIGLSYPGGPQVDKLAAEGEDTYDFPRVWLEQDSFDFSFSGLKSAVINKLHNLKQKNEAIIPENVATSFQNSVVEVLVGKAIKACETYNVHQLIVAGGVASNKGLRQELKKACAEHDIKLSIPSPKLCTDNAAMIGAAGHYMYEAGMRSDMHLNGHSSLDIEDFSVEKE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SET1_CRYNB
Sequence: MAPHEKGVNPSESPSGSLKKAPPSGPKALRGFASPSAFRNAGIGNGLLQHRGEDERISFAFPRKGKESLDRNGERPAPMSLESRLGPPVSRFNRPVGGDSLERGNGKGGWDNRDERTSASSSSIHRINKEKIRPRSDFIESSANLYSEDDRNRDRGRYHERDRSRGTNGDRGGGEGHSHREPGRGKEHQNGQGRDRSLYRDHSRERESSRDERDRYSEEYKHQRSKARFSPSPSPERSRLKSSLGRHRSPVSVSSSSSSSARSPPPVQNREPLRYNGSQSKNGEKELSNGLLENSISRSGVSIAVPRKLETKQLVRPSPPHVNLKSTIQDNPSPPTGKYPPSPPSLDILSKPSCNREPLPDQRPPTPPLPENSSPTSPSLESSRFDQNQHLLPDELPLPPLSISFPQKPVSSSSLSRLSSLSAALSRPNPLDKDGTSMPPSFHFREISNRHQRLSPPNNAENQLPETSIIPPPPSETVPEPPWIRPPYIPPPCTKHRPGIGNFFITNLREKVEDKSGKEEKRVDGMEGGKVVQVTDPRLSMTEEQRGRGRGSSKQRAAFYELTYEWDLYSVTPKPPSPPTAVLITGLGPLTTVDQITKFLRPHGRIKEIDSKVDRKTDMQLGICWVKFEGPPLGRPGTAHDVASMAVKVCDGKKISMGGERIRVVLDGRGKRAEQAVKEEMERRYPPKKPSALPSDMKVTPLSGTAMATTSRPPNAPNASTPLIDKQTFDTSAKAPIIRPGVLKPLGQKMYHRPSAPPLVFNNHRFRDESFLNRPFNAGAGMISQQQMGYKILPGKPVQQLASSFTSAPFVRHPRERREDSWTNERGRRLKGESSTRHWRARSLSRSSYSSYSSYSSYSEESEEERPRHPTKVPYPQRKRLATGPSKEDEYKMEDVREAIRENGHPCVFIDAKSLPAAREYESRQSHLGWYILFADDTTAYRVQRVLDTTAVQGHRLSLVVHTSSGPRAQTDASEPVTGGVGESKKGNWRYLTITKKSRPMPAVKKSGKSATIRRKVYSPSVSGSDDDDEQVPVMAQNRKRAPSYASSTSPLSEDDRPFARSVQREERDIDKEGKFSLIGKKADVVSVKAAKGPKSKTIRVDSDEVEENQGVPLASIGEVTKAEGKQDDSTVVKLETLLSESISELTKGKKRPTKAKGGKATKKVRLDQEADDAATKIQIDEDIVPQPPKKKKVVKTEVDKLLASGVLMDEEDAYWLGRVLAAQEDGLEPIWSDGEEDLVDEGHPLFHKSGAWRAEGWKKVAQVQKSRYLPQRNRAVVNSEDVGGITTGRTARLAGRDQHRQTAAVAANNTVESDLFAFNQLRIRKKQLRFARSAIEGYGLYAMETIHAGEMVCEYVGDLVRATVADVREQRYLKQGIGSSYLFRIDNDIVCDATFKGSVSRLINHSCDPSANAKIIKVNGQSKIVIYAERTLYPGEEILYDYKFPLESDPALRVPCLCGAATCRGWLN
What is the function of this protein?
Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-4 specific, COMPASS component SET1, SET domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SCDA_STAA2
Sequence: MINKNDIVADIVIDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKSGMLEHMQKEDDVDFPKLIKYEQGEVVNDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein ScdA.
What is the protein family that this protein belongs to?
Belongs to the RIC family. ScdA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_PSEAB
Sequence: MTNKIIQQIEAEQMNKEIPAFAPGDTVIVQVKVKEGDRQRLQAFEGVVIAKRNRGLNSAFTVRKISNGVGVERTFQTYSPIVDSLSVKRRGDVRKAKLYYLRALSGKAARIKEKLV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL3_ACTSZ
Sequence: MIGLVGRKVGMTRVFTEDGVSIPVTVIEIEANRVTQVKTLENDGYTAVQVTTGSKKASRVTKPEAGHFVKAGVEAGRGLWEFRTEGEEFTLGQEINVDIFADVKKVDVTGTSKGKGFQGGVKRWNFRTQDATHGNSLSHRVLGSIGQNQTPGRVFKGKKMAGHLGAERVTVQSLEVVRVDAERKLLLVKGAVPGATNSDVIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: TRMD_NEIMF
Sequence: MLIQAVTIFPEMFDSITRYGVTGRANRQGIWQFEAVNPRKFADNRLGYIDDRPFGGGPGMIMMAPPLHAAIEHAKAQSSQAAKVIYLSPQGKPLTHQKAVELAELPHLILLCGRYEGIDERLLQSSVDEEISIGDFVVSGGELPAMMLMDAVLRLVPGVLGDMQSAEQDSFSSGILDCPHYTKPLEFQGMAVPEVLRSGNHGLIAEWRLEQSLRRTLERRPDLLEKRSLIPKESRILNKILQEQREIQS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_SHESR
Sequence: MPLTWKDSGLRWYWVVVLVFLADQLSKQWVLANFDLFESVKLLPFFNFTYVRNYGAAFSFLSEAGGWQRWLFTLVAVGFSTLLTVWLRKQSASLWKLNLAYTLVIGGALGNLIDRLMHGFVVDFIDFYWGKSHYPAFNIADSAIFIGAVLIIWDSFFNSKSEQDKTEEVK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECA_HELP2
Sequence: MAIDEDKQKAISLAIKQIDKVFGKGALVRLGDKQVEKIDAISTGSLGLDLALGIGGVPKGRIIEIYGPESSGKTTLSLHIIAECQKNGGVCAFIDAEHALDVYYAKRLGVDTENLLVSQPSTGEEALEILETITRSGGIDLVVVDSVAALTPKAEIDGDMGDQHVGLQARLMSHALRKITGVLHKMNTTLIFINQIRMKIGMMGYGSPETTTGGNALKFYASVRIDIRRIASLKQNEQHIGNRAKAKVVKNKVAPPFREAEFDIMFGEGISKEGEIIDYGVKLDIVDKSGAWLSYQDKKLGQGRENAKALLKEDKALADEITLKIKESIGSNEEIMPLPDEPLEEME
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_YERPG
Sequence: MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMRAAGCVVNDYADRHIDGFVKRTASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIWLSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAAVSESLPLVCWLLLLANICWTVAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFYWSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLVLFLGILISYW
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS18_ARTS2
Sequence: MAKAELRKPKPKSNPLKAADITVIDYKDVALLRKFISDRGKIRARRVTGVTVQEQRKIAQAIKNAREVALLPYSGAGRG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GLGL2_MAIZE
Sequence: MQFSSVLPLEGKACMSPVRRGSGGYGSERMRINCCSIRRNKALRRMCFSARGAVSSTQCVLTSDAGPDTLVRPNHPFRRNYADPNEVAAVILGGGTGTQLFPLTSTRATPAVPIGGCYRLIDIPMSNCFNSGINKIFVMTQFNSASLNRHIHRTYLGGGINFTDGSVEVLAATQMPGEAAGWFQGTADAVRKFIWVLEDYYKHKAIEHILILSGDQLYRMDYMELVQKHVDDNADITLSCAPVGESRASDYGLVKFDSSGRVIQFSEKPKGAALEEMKVDTSFLNFATCTLPAEYPYIASMGVYVFKRDVLLDLLKSRYAELHDFGSEILPKALHEHNVQAYVFTDYWEDIGTIRSFFDANMALCEQPPKFEFYDPKTPFFTSPRYLPPTKSDKCRIKDAIISHGCFLRECAIEHSIVGVPSRLNSGCELKNTMMMGADLYETEDEISRLLAEGKVPIGVGENTKISNCIIDMNCQGWKERLHNKQRGRSKSPDRPGRRILIRSGIVVVLKNATIKDGTVI
What is the function of this protein?
This protein plays a role in synthesis of starch.  It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic/amyloplastic, ADP-glucose pyrophosphorylase, ADP-glucose synthase, AGPase S, Alpha-D-glucose-1-phosphate adenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Found in the chloroplast in leaf. Found in the plastid in developing endosperm.
Protein: ASCC2_HUMAN
Sequence: MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
What is the function of this protein?
Plays a role in DNA damage repair as component of the ASCC complex.  Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457).  Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347).  Involved in activation of the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation (PubMed:32099016).  As part of the ribosome quality control trigger (RQT) complex, recognizes ZNF598-dependent ubiquitination of stalled ribosomes (By similarity).
What are the official names of this protein?
Activating signal cointegrator 1 complex subunit 2, ASC-1 complex subunit p100, Trip4 complex subunit p100.
What is the protein family that this protein belongs to?
Belongs to the ASCC2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Colocalizes with the spliceosomal components PRPF8 and SNRNP200/BRR2 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage. Colocalizes with RNF113A and 'Lys-63'-linked polyubiquitinated proteins, ALKBH3 and ASCC3 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage.
Protein: SYE_CAUSK
Sequence: MTNSPAPTTSGVVTRFAPSPTGFLHIGGARTALFNWLYARHTGGKFLVRVEDTDRERSTQAAVAAIFEGLDWLGMKSDEEVVFQHKKADRHREAVQQLLDTGRAYRCWMSVEDLALAREAARAGGPALRSPWRDAPPPNDPTAPHVIRFKGPLDGTTLVDDLVKGPVTFDNAELDDLVLLRADGAPTYNLAVVVDDHDMGVTHVIRGDDHLNNAARQTLIYQAMGWTLPAFGHIPLIHGPDGAKLSKRHGAQAVGEFQDMGYLPEGLRNYLARLGWGHGDDEVFSDAQAIEWFDVKDVVKAPARLDWAKLNFINSQHLHVAEDGRLADLTLKALQAQGAPLPDDAPARLLATVPQVKVGAKTILELAEHCAFALKVRPLALEEKTRNQLTDETVDRLKRLRAQLGAVPVWGLSELEVLLKSFAESEGVGFGKFGPSLRGILTGGSQAPDLNKIMTALGREESLGRLDDALASRA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_NANEQ
Sequence: MWRQRRKWEGPSHPWQKQRLIIEKRLMKEYGLKNKRELWIAETIARKWRAYARYLNAKQAAGQDISEEKERFLTKLKKLGVLSENAELDDVLDLTVKDVLERRLQTMLVRKGLAKTMKQARQFIVHGHIMVNGEVVDAPSYLVKKEEEDKIEFVPFSPLANPEHPARKLEQKEETNEESA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TPIS_PSEU2
Sequence: MRRPMVAGNWKMHGTRASVAELIEGLCKQSLPGSVDIAVMPASLFTCQVVDGLKATSIIVGAQDAAIQAEQGALTGEVASSQLADAGCKLVLVGHSERRQLIGEQDDVLNKKFAAIQAKGLTPVLCVGETLEERKAGQTLEVVGRQLDSVIAEFGVNALVNAVIAYEPVWAIGTGLTASPQEAQEVHAAIRAQLAKENAEVAQGVRLLYGGSVKAANAVELFSMPDIDGGLIGGASLNADEFGAICRAAGN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.