PharMolix/UniProtQA huggingface dataset:
Protein: RS2_MAIZE
Sequence: MKERQRWRPEEDAVLRAYVRQYGPREWHLVSQRMNVALDRDAKSCLERWKNYLRPGIKKGSLTEEEQRLVIRLQAKHGNKWKKIAAEVPGRTAKRLGKWWEVFKEKQQRELRDSRRPPPEPSPDERGRYEWLLENFAEKLVGERPQQAAAAPSPLLMAAPVLPPWLSSNAGPAAAAAAAVAHPPPRPPSPSVTLSLASAAVAPGPPAPAPWMPDRAAADAAPYGFPSPSQHGGAAPPGMAVVDGQALAELAECCRELEEGRRAWAAHRREAAWRLKRVEQQLEMEREMRRREVWEEFEAKMRTMRLEQAAAAERVERDHREKVAELRRDAQVKEEKMAEQWAAKHARVAKFVEQMGGCSRSWSSATDMNC
What is the function of this protein?
Transcription factor required for normal cell differentiation.  Interacts directly with asymmetric leaves 2 (AS2) to repress the knox homeobox genes.
What are the official names of this protein?
Protein rough sheath 2, Protein PHANTASTICA, ZmPHAN.
Protein: UREE_RHOPB
Sequence: MIRATSVKGQHRWSEAAADTVVLDFDDRHRRRTAMVGTRGLQFLLDLEHAVALRGGDALVLEDGRLVEVVAAAEPLIEIRGSDPKELVRIAWHLGNRHLPTQIMAKGLRIRRDHVIEEMVQGLGAKTVEIEAPFDPEGGAYAPPAEPSHDHAGHDHAHDSHAHHDHDHGKHAQHDHGKHDHAHHDHAAHDDHHVHDEHCGHDHHGHGHEHK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_VIBCM
Sequence: MNQSSLLAEFGDPITRVENALQALREGRGVLLLDDEDRENEGDIIYAVESLTTAQMALMIRECSGIVCLCLTEAQADRLALPPMVVNNNSANQTAFTVSIEAKHGVTTGVSAQDRVTTIKTAANPQAKPEDLARPGHVFPLRARAGGVLARRGHTEGTVDLMQMAGLQPAGVLCELTNPDGSMAKTPEIIEFGKLHNMPVLTIEDMVQYRIQFDLKLA
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: ATPB_SINFN
Sequence: MAKAATPKETAAVKKPAAPKKAATAKTTAVVATGAVGRVTQVIGAVVDVAFEEGQLPQILNALETDNKGNRLVLEVAQHLGENAVRTIAMDSTEGLVRGQSVTDTGGPISVPVGKETLGRIMNVIGEPVDEAGPVETSSRRAIHQDAPAYVEQSTEAQILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVNKHGGGEGSKAALVYGQMNEPPGARARVALTGLTIAEHFRDEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGQMQERITTTTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRMLDPMIVGEEHYEVSRKVQSTLQRYKALQDIIAILGMDELSEEDKVAVARARKIERFLSQPFFVAEVFTGSPGKLVALEDTIKGFKGLVNGEYDHLPEAAFYMVGSIDEAIEKAKKLAAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYL_BACC7
Sequence: MSFNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEIIDGKSERGGHPVERRPMRQWMLKITAYGDRLLEDLDELDWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKFTVFTTRPDTLFGASYCVLAPEHALVADITTAEQKEAVEAYINSVKMKSDLERTELAKEKTGVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVKGGDITKEAYTGDGEHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTMTAVKEEELPLVLPKTDNIRPSGTGESPLANIDEWVNVVDPETGKKGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDIGVVPTKEPFQQLFNQGMILGENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLDRVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAYKAETLPKEYVEGFVKMIAPVAPHIGEELWSKLGYNETITYASWPTFDESKLVEDEVEIVVQVMGKVRAKLTMSKDASKEEMEQLALEAIKDQIEGKTVRKVIVVPGKLVNVVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_CRYNJ
Sequence: MTAVSLSDGTAVLKTDPWLEPFSGALRERYAAYQKQRTIIEEHEGGLAEFSKGYKSMGFQIDKNGGVRYREWASNATEARLIGEFNNWSHTANPMTKSPFGVWECYVPPVSPGVCAIPHDSMVKISMTLPGGESIDRIPTWITRVTQDLNISPIYDGRFWNPPKEQQYQFKHGHSTRPVEGLKIYEAHVGISSPNMRVTTYKEFEVDVLPKIKQLGYNCIQMMAIMEHAYYASFGYQVTNFFAASSRFGTPEELKSLVDKAHELGLTVLLDVVHSHASKNILDGINMYDGSDHLYFHEGGRGRHDQWDSRLFNYGQHEVLRFLLSNLRFWMDIYMFDGFRFDGVTSMMYKHHGIGSGFSGGYHEYFGDSVDLEAMVYLMLANAMLHETYPHVVTIAEDVSGMPTLCRPVAEGGVGFDYRLSMAIPDMWIKLLKEYTDDQWEMGQIVHNLTNRRHLEKSVAYAESHDQALVGDKTLAFWLMDKEMYDFMSDLSPLTPIIDRGLALHKMIRFIVHTLGGEAYLNFEGNEFGHPEWMDFPREGNGNSFAHARRQFNLVDDKLLRYKYLYEFDVAMNWLEDKYKWLNSPQAYVSLKHEGDKMIVFERAGLLFIFNFHPTQSFTDYRVGVDTAGEYKVILTSDETRFGGHNRIDMGGRYFTTPMEWNGRKNWLQVYSPSRTVLVLGL
What are the official names of this protein?
1,4-alpha-glucan-branching enzyme, Glycogen-branching enzyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: PYRB_XANOM
Sequence: MTTMQLDSDGRLRHLLTLEGVPRTTLLQLLDRAGQIRDAAVGRVGKRSVLAGTAVCTLFFEPSTRTRSSFHLAAQRLGADVLNFDASTSSTRKGETARDTLKNLEAMGVRGFVVRHPDDGAVKALAAAAGEGTALINAGDGRSAHPTQGLLDMLTLRQAKGTDFSKLKVVIVGDVKHSRVARSDLHALRTLGAGEIRVCGPASLLPDDGILEGCVVGQDFDAMLEGADALMMLRLQRERMEEGLVPSLEQYHTEYGLTRERLARAGHDAAVLHPGPINRGVEITDEVADGAQSCVLRQVANGVAVRMAVLETLLG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TATB_NITEU
Sequence: MFDISFAELVVVGIVALIVIGPERLPAVARTAGYFLGRARRYVDQVKHDLHEEMELDSLRKLRDSMHETVNSFENSVRSEINKIQETTETQSAVIPDKQPPFEKAAENIEPVNTSETKTSSAPAEPRQPNS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YE175_YEAST
Sequence: MRLHKTFICFSQNKRGCRNILQENSRMIFENKILIMILRQGIFFNISVSTKISF
What are the official names of this protein?
Uncharacterized protein YER175W-A.
Protein: YIDD_BURP6
Sequence: MQTVLIALLRFYKLAVSPLLGSRCRFYPSCSDYAREAIQYHGAARGTYLAARRLCRCHPFSAGGVDLVPPPNSDARNAPHEAEASSHRL
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RK34_THAPS
Sequence: MTKRTLSNKTRSSILKVSGFRARMATAQGRKIIRTRRQKGRKKLAIPR
What are the official names of this protein?
50S ribosomal protein L34, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PURE_ARCFU
Sequence: MSQFLSLRNCLRLTIRLLRQFRRGEGMKAVIIMGSKSDLDYSKKIASKLADFGIDAVMRIASAHKTPEKVLEIIKEYEKEDVVFVTVAGRSNALSGFVDANTSKPVIASPPYSDKFGGADIFSSIRMPSGVAPMLVLEAENAALAVAKIFALKDEGVREKVVQFQENKRREIYKADEELR
What is the function of this protein?
Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
What are the official names of this protein?
Phosphoribosylaminoimidazole carboxylase, AIR carboxylase, AIRC.
What is the protein family that this protein belongs to?
Belongs to the AIR carboxylase family. Class II subfamily.
Protein: SYS_ACICJ
Sequence: MHDLKAIRDDAAAFGAAMRRRGLAGPEGADEGAAAPIRALDEERRRAQTELQGHETRRNELARAIGQAKRAGEDTTALEAEGTALRQSIETANAWLAESARKLDELLAVLPNVLDADVPDGPDETANVEQKRVGAPPSFDFEARQHFELGEALGLMDFAGAAKLAGARFTVLRGDLARLERALGQFMLDLHVNEHGYTEVSPPLLVNDATMYGTGQLPKFAEDLFRTTDGRWLIPTAEVPLTNLAAGEILDAASLPLRMTALTPSFRSEAGSAGRDTRGMLRQHQFWKVELVSLTTPEASADEHERMTSCAESVLERLGLPYRRMLLCAGDTGFSSAKTYDLEVWLPGQGAYREISSCSNCRAFQARRMNARYRPPQTGPKPAKPDFVHTLNGSGVATGRALIAVMENYQNADGSITVPDALRPYMRGCDRIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SG196_RAT
Sequence: MGQQHGARNGLTHRELPRGMGLLLAMALMNVVLYVCLDHLFISPGRATEDPRRCPPGYFRMGRMRNCSRWLSCEELRTEVRQLKLVGEGAVKRVFLSEWNEHKVALSRLTRLEMKEDFLHGLRMLTSLQSQHVVTLAGFCEEDGTILTEYHPLGSLSNLEETLNLSKYRDVNTWQHRLRLAVEYVSIINYLHHSPLGTRVMCDSNDLPKTLSQYLLTSNFSIVANDLDALPLVDHGSRVLVKCGHRELHGDFVAPEQLWPYGEDTPFQDDLMPPYDEKIDIWKIPDVSSFLLGHVEGSDMVRFHLFDIHKACKNQFPAERPTAQNVLDAYQKVFHSLRDTVMSQTKEML
What is the function of this protein?
Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose).  Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.  Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif (By similarity).
What are the official names of this protein?
Protein O-mannose kinase, POMK, Protein kinase-like protein SgK196, Sugen kinase 196.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: RANB9_MOUSE
Sequence: MSGQPPPPPPQQQPPPPPPPASAAAPATAPPGLAVGPGPAAGVPVPGLAAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDANFGQHPFVFDIEDYMREWRTKIQAQIDRFPIGDREGEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRIQKLVLAGRMGEAIETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPVSPRPFSSPSMSPSHGMSIHSLAPGKSSTAHFSGFESCSNGVISNKAHQSYCHSKHQLSSLTVPELNSLNVSRSQQVNNFTSNDVDMETDHYSNGVGETSSNGFLNGSSKHDHEMEDCDTEMEVDCSQLRRQLCGGSQAAIERMIHFGRELQAMSEQLRRECGKNTANKKMLKDAFSLLAYSDPWNSPVGNQLDPIQREPVCSALNSAILETHNLPKQPPLALAMGQATQCLGLMARSGVGSCAFATVEDYLH
What is the function of this protein?
May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways.  Acts as a mediator of cell spreading and actin cytoskeleton rearrangement.  Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.  May be involved in signaling of ITGB2/LFA-1 and other integrins.  Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway.  Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation.  Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity.  Inhibits the kinase activity of DYRK1A and DYRK1B.  Inhibits FMR1 binding to RNA.
What are the official names of this protein?
Ran-binding protein 9, RanBP9, B-cell antigen receptor Ig beta-associated protein 1, IBAP-1, Ran-binding protein M, RanBPM.
What is the protein family that this protein belongs to?
Belongs to the RANBP9/10 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Note=Predominantly cytoplasmic (PubMed:18710924). A phosphorylated form is associated with the plasma membrane (By similarity). Perinuclear in spermatids (PubMed:14648869).
Protein: CAMP_NAJAT
Sequence: MEGFFWKTLLVVGALTISGTSSFPHKPLTYEEAVDLAVSVYNSKSGEDSLYRLLEAVPALKWDALSESNQELNFSVKETVCQMAEERSLEECDFQEAGAVMGCTGYYFFGESPPVLVLTCKSVGNEEEQKQEEGNEEEKEVEKEEKEEDQKDQPKRVKRFKKFFKKLKNSVKKRAKKFFKKPKVIGVTFPF
What is the function of this protein?
Potent antimicrobial peptide against most of Gram-negative bacteria, some Gram-positive bacteria (Bacillus) and some fungi.  Adopts an amphipathic alpha helical conformation, that may allow to partition into the target membrane.  No hemolytic and cytotoxic activities have been observed on mammalian cells.
What are the official names of this protein?
Cathelicidin-related antimicrobial peptide Na_CRAMP, Cathelicidin-NA antimicrobial peptide, Vipericidin.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: RL22_MYCGI
Sequence: MTTAIQYPSASAKARFVRVSPTKARRVIDLVRGKSVEDALDILRWAPQAASEPVAKVIASAAANAQNNEGLDPSTLVVATVFADEGPTAKRIRPRAQGRAFRIRKRTSHITVIVESRPAKKQGASASAARARRAQASKAASQKEGSE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: OGG1_ARCFU
Sequence: MIEKAISRRIKEFRQLGEKGEVEFDFRPFLDFSVKATIRTELAFCISTANSSATAGLKFQRLLGQGVGVKEALTLAGVRFHNRKAEYIREAFKSFKLVEKALEAESSKAREILLKIKGLGMKEASHFLRNVGREDVAIIDRHILRWLERQGYEVPGTMTAKKYLEVEKILMEISEERGESLAEMDLRIWAEMTGKVLK
What is the function of this protein?
Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA.  Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).  Efficiently cleaves oligomers containing 8-oxoG:C and 8-oxoG:G base pairs, and is less effective on oligomers containing 8-oxoG:T and 8-oxoG:A mispairs.
What are the official names of this protein?
8-oxoguanine DNA glycosylase/AP lyase.
What is the protein family that this protein belongs to?
Belongs to the type-2 OGG1 family.
Protein: YQGF_BARBK
Sequence: MAIITIDRVISHLLSKQTIAGLDLGTKTIGIAISDISLTFSNPRPVIQRKKFTLDALKLIKIFDHENVGVAIIGLPINMDGSNGPRVQATRTFVSNIAMYTKIPFIFWDERLSTIAAQRHLLEIDVSRIKRENRIDSAAAAFILQGALDRIQILRQNHTEG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_METSB
Sequence: MPSKQSDIKKVVLAYSGGLDTSIILKWLETTYGCEVVTFTADLGQGEEIEPARQKAILLGVKPENIFIEDLREEFVRDYVFPMFRANAQYEGLYLLGTSIARPLIAKKQIEIAKKTGADAVAHGATGKGNDQVRFELSYYALDPDIKVIAPWREWDLTSRTALIAFAEQHQIPIAKDKRGDAPFSVDANLLHASSEGKVLEDPAEEVPDYVYSRTVNPEDAPDKPTYIEIDFERGDPVAIDGEALSPANLLTRLNELARVNGVGRLDLVENRFVGMKSRGMYETPGGTILYVAHRGIESITLDRGAAHLKDELAPKYSELIYNGFWFSPEREMLQALIDKSQEFVAGRVRVKLYKGSAVVVGRSSPYSLYDQDLVTFEEGAVAYDHRDAAGFIKLNALRLRTLGKRARKIAAAQKA
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBA_XYLFA
Sequence: MNTPTHTHPHPFGSTATIRCERAAAELRTGRPVLLIDAHTRRHAVMALDSMTAQSFTTFANAVGNTHYLFLTPARSNVLGLEAPQGARIPLATLSYDSLVKLAYLRQPTHPTTWVPGDIMDAAATEITRLALLLPAIVAAPLTHHTEHAFADCQTLDLTDLDTAAAGASTTEYELVTRTPVPLRDLGMSEFIVFRGGIAQRDQVAILIGQPDLSSAVPVRVHSSCLTGDLFGSLKCDCGDQLRHGLATLKALGGGVLLYLDQEGRGNGIAAKIRAYGYQHVGLDTIDADAQLGFGPDERRYTGAVMMLRALGITRIQLLSNNPTKVERLRAAGIIVEQRIPVIGQITEQNEYYLRTKVSRAGHDLDIDALIMTSQRPQDPSETVDGETVKSIPKTGHA
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: OPH_SPHS1
Sequence: MFKPVVKSRSSRSFCYLAGCLAMVAATLSSTAQAKSEWACPEGFTPKAGLNTDFPSDGKKRAFVVVPPKDSAGGAPVWVPMVGTVEATNWNLNVPRSGNNAKLAEHGYMVISPVRQCAEQDPNLGAGACNGVGKDGWTWNPWNDGRAPDASGDKYKTDAGDDVRFLEAMVRCVGTKWKLDRKRLFLGGISAGGTMTNRALLFDSEFWAGGMPISGEWYSTKDDGSTVPFQETRKMVAAAPAKIWQGRVGPYPLPSKLDPMVVITVWGGEKDLWDCGPPLGLCSDYRPTTQASSNYFSSISNVVHVACSATHGHMWPQVNTDAFNLWALNTMASHPKGSSPKDFKLTAPPEGYSCKIGRFTDHYK
What is the function of this protein?
Catalyzes the hydrolysis of 4,6-nonanedione, a beta-diketone compound.  Also mediates hydrolysis of oxidized polyvinyl alcohol (PVA) in the second step in the degradation of polyvinyl alcohol.  Not active toward the monoketone structure.
What are the official names of this protein?
Oxidized polyvinyl alcohol hydrolase, OPH, Oxidized PVA hydrolase, Beta-diketone hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9A family.
What are the subcellular locations of this protein?
Periplasm.
Protein: BXI1_SCHPO
Sequence: MPANYQSVPQDDPSVPNLAQAPPAYSEYNESATENPAVDQFKNTTPVAECAKSIRMAFLRKVYAILTAQLFVTSLFGGIFYLHPAFSFWVQMHPWFLILNFFISLVVLFGLIMKPYSYPRNYIFLFLFTALEGLTLGTAITFFSARIILEAVFITLGVFVALTAFTFQSKWDFSRLGGFLYVSLWSLILTPLIFFFVPSTPFIDMAFAGFGTLVFCGYILFDTYNILHRYSPEEFIMSSLMLYLDFINLFIRILQILGMLQNNDNN
What is the function of this protein?
Links the unfolded protein response and programmed cell death and mediates mitochondrial-dependent apoptosis.  Induces cell death and disruption of the mitochondrial transmembrane potential (By similarity).
What are the official names of this protein?
Bax inhibitor 1, BH3 domain-containing protein bxi1.
What is the protein family that this protein belongs to?
Belongs to the BI1 family. LFG subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: ACCA_CHLPM
Sequence: MATKVVLDFEKPLVELEAKLGEMRHCLRSSSREQAPNEAEALQNEIGTLEKKVEALRQSIYKNLTRWQKVQLARHPERPYTLDYIYMITCDFVELAGDRHFSDDKAIVGGFARIEDRVSGFSQPVMVIGHQKGRDTKSNLYRNFGMAQPEGYRKALRLMKLAEKFRKPIITLIDTPGAFPGIEAEERGQAEAIARNLYEMAKLTVPVICVIIGEGASGGAIGLGVGDRILMAENSWYSVISPESCSSILWRSWNYKEQAAEALQLTAPDLLSQGIIDRIVPEPMGGAHTAPEAMAGTLKGILIEELSALLPLSSEELVNSRIEKFSSMGVWNEEG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_ECTVM
Sequence: MSRGALIVFEGLDKSGKTTQCMNIMESIPSNTIKYLNFPQRSTVTGKMIDDYLTRKKTYNDHIVNLLFCANRWEFASFIQEQLEQGITLIVDRYAFSGVAYAAAKGAPMTLSKSYESGLPKPDLVIFLESGSKEINRNVGEEIYEDVEFQQKVLQEYKKMIEEGDIHWQIISSEFEEDVKKELIKNIVIEAMHTVTGPVGQLWM
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: L2MU_ADEB2
Sequence: MTGVPRVTYRVRVPVRTRVLRPRRHGRLVRRVARRKSMRGGFLPFLVPLIAAAIGAAPGIASVALQASRR
What is the function of this protein?
The role of the precursor might be to condense the viral prochromatin for encapsidation by virtue of the two basic domains.
What are the official names of this protein?
Late L2 mu core protein, Protein X, pX, pMu.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae pX family.
What are the subcellular locations of this protein?
Virion.
Protein: NUOI_PSEPK
Sequence: MFKYIGDIVKGTGTQLRSLAMVFSHGFRKRDTLQYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETEDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMAEFKRQDLVYEKEDLLISGPGKNPDYNFYRVAGMAIAGKPKGSAQNEAEPINVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SDHF2_PICGU
Sequence: MSVRRIAIRCLNYGKPQNPAYNASSSMRIEPIKRTGETRETKKARLVYQSRKRGILESDLLLSRFAKKHLDSLSDSQLDEYDQLLDEPDWDIYYWATKNYDVTPLPDRWKDSEILKMLQKDAQNEDREIMRMPEL
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL7_YERPP
Sequence: MSTITKDQILEGVAALSVMEIVELISAMEEKFGVSAAAVAAGPAAAVEAAEEQTEFDVVLASFGENKVAVIKAVRGATGLGLKEAKDLVESAPAVLKEGVNKDEAETLKKSLEEAGASVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RL332_MYCGE
Sequence: MRKKIIFVCQDCLSRNYVKRWTKQPLQRLIINKYCKQCNQKTKHLDSF
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.