PharMolix/UniProtQA huggingface dataset:
Protein: KCND3_RABIT
Sequence: MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKSKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTASLIESQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHAGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTSQITTAIISIPAPPALTPEGETRPPPASPGPNTNIPSIASNVVKVSVL
What is the function of this protein?
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels.  May contribute to I(To) current in heart and I(Sa) current in neurons.  Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
What are the official names of this protein?
Potassium voltage-gated channel subfamily D member 3, Voltage-gated potassium channel subunit Kv4.3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.3/KCND3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection, dendrite. Note=Interaction with palmitoylated KCNIP2 and KCNIP3 enhances cell surface expression.
Protein: LON_VIBPA
Sequence: MNLERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSISCLETAMETNKQVLLVAQKQADTDEPTVDDLFEVGTVATILQLLKLPDGTVKVLVEGQQRAKINHFKESDFFLAEAEFIVTPELDEREQEVIVRSAINQFEGFIKLNKKIPPEVLTSLNGIDEAARLADTIAAHMPLKLVDKQQVLEIIDVTERLEFLMGQMESEIDLLQVEKRIRGRVKKQMEKSQREYYLNEQMKAIQKELGEMEDAPDEFETLQKKIDESKMPQEAREKTEQELQKLKMMSPMSAEATVVRSYIDWMVSVPWTKRSKVKKNLAKAEEILNEDHYGLERVKERILEYLAVQNRINKLKGPILCLVGPPGVGKTSLGRSIASATGRKYVRMALGGVRDEAEIRGHRRTYIGSLPGKLIQKMSKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNNSFNDHYLEVDYDLSDVMFVATSNSMNIPGPLLDRMEVIRLSGYTEDEKLNIAKRHLVEKQVQRNGLKPNEIVIEDSAIIGIIRYYTREAGVRGLEREISKICRKAVKNILLDKDIKSVTVTMDNLKEYLGVQRFDYGKADESNRIGQVTGLAWTEVGGDLLTIETQSMPGKGKLTQTGSLGDVMQESIQAAMTVVRSRADKLGINSDFYEKKDIHVHVPEGATPKDGPSAGTAMCTALVSALTGNPVKAEVAMTGEITLRGEVLPIGGLKEKLLAAHRGGIKTVLIPKDNERDLEEIPENVIADLQVIPVQWIDEVLKVALERDPTGVEFEAKK
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner (By similarity).  Regulates swarmer cell differentiation of V. parahaemolyticus.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_PSEFS
Sequence: MHSYDYWLIIAFFAVVLVPAPFLGRFYYKVMEGQRTWLTPVLGPVERACYRLSGVDEQQEQSWQKYMLALLAFNLAGFLLLFAILLFQDYLPLNPQKLPGQEWTLAFNTAVSFMTNTNWQSYSGEASLSYLSQMAGLTVQNFVSAATGLAVLVALCRGIGRKSTKTLGNFWVDMTRATLYGLLPLCLVLALFLVWQGVPQTFAHYVDAVTMQGVDQVIPLGPAASQIAIKQLGTNGGGFFGVNSAHPFEDPTAWANLFELAAIILIPVALVFTFGHYVKDLRQSRAILGCMLALFLIGGATSLWAEYQPNPTLNNPAVEQAAPLEGKEARFGTTGTVLWSVTTTAASNGSVNGMQDSLNPLSGMVALVNMMVGEVIFGGVGAGMYGMLLNVLIAVFLAGLMIGRTPEYLGKKLQAKEVQLLVVTLLVMPVGVLVLGAIAASLPGPAGAISNPGPHGFSQLLYAYTSASANNGSAFGGFSANTPFHNLMLGLGMLIGRFGYILPVLALAGSLAMKKTAPIGQNSFPTHGPLFVTLLTVTILLVGGLTFLPTLALGPIAEHLSMGF
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYR_SYNS3
Sequence: MLRIAQALDTQLREAMQRAFPDVDALLDPQLAPANKPEFGDFQANGALPLAKPLKQAPRLIAGAIVEALQADPAFAALCLEPQIAGPGFINLTIRPERLAAEVSARLGDPRLGVPEVQSDAAVVVDFSSPNIAKEMHVGHLRSTIIGDSLARVLEFRGHRVLRLNHVGDWGTQFGMLITHLKQVAPETLNRADAVDLGDLVAFYREAKKRFDEDEAFQATSREEVVKLQGGDPVSLKAWGLLCDQSRREFQKIYDRLDIRLSERGESFYNPYLASVLSGLKEADLLVTDDGAECVFLEGVNGKDGKPLPVIVRKSDGGFNYATTDLAAIRYRFALAPDGDGARRVIYVTDAGQANHFAGVFQVAKRANWIPEHGRLEHVPFGLVQGEDGKKLKTRSGDTVRLRDLLDEAVERAEADLRRRLEEEGRSEDDQFIEHVAGTVGLAAVKYADLSQNRITNYQFSFDRMLALQGNTAPYLLYAVVRIAGIARKGGDLEAEAGMLQFSEPQEWSLVRELLKFDAVIAEVEEELLPNRLCSYLFELSQVFNRFYDQVPVLKAEGQSLPSRLALCRLTADTLKSGLGLLGIATLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_WOLPM
Sequence: MNELRKLSITQMHDGLKKKSFSAVELVEAHISAVENEKLNAFITKTPEIAMKAAKAADEHFSRQKDDLISPLMGVPVGIKDLFCTKGIKTTACSKMLENFVPTYESTVSDLLLKSGAAMLGKLNMDEFAMGSANTNSYFGPVENVWIRKSDGEKVVPGGSSGGSAASVAGFLCAGALGSDTGGSVRQPAAYCGVVGIKPTYGRCSRFGMIAFASSLDQAGVITRSVSDSALMLEAICGYDTKDSISSEKPVPKFSSFINGDVKGKRIGIPKEYRMDGISEEIVHNWEKVASYLKENGAEVVDVTLPHTKYAIPVYYLICSAETSSNLARYDGVRYGFRVDADTLEEMYSLTRAEGFGKEVKRRILIGAYALSSGHYNEYYEKAQCIRALIRNDFIKAFEKIDYILVPSAPTEAFGLNEKPDPLIMCINDVFTVPASLAGLPAISVPVGLSNEGLPLALQVIGNYYDEAGILNVASVIEQNCGRIIRPLA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: 1A17_ARATH
Sequence: MGLPLMMERSSNNNNVELSRVAVSDTHGEDSPYFAGWKAYDENPYDESHNPSGVIQMGLAENQVSFDLLETYLEKKNPEGSMWGSKGAPGFRENALFQDYHGLKTFRQAMASFMEQIRGGKARFDPDRIVLTAGATAANELLTFILADPNDALLVPTPYYPGFDRDLRWRTGVKIVPIHCDSSNHFQITPEALESAYQTARDANIRVRGVLITNPSNPLGATVQKKVLEDLLDFCVRKNIHLVSDEIYSGSVFHASEFTSVAEIVENIDDVSVKERVHIVYSLSKDLGLPGFRVGTIYSYNDNVVRTARRMSSFTLVSSQTQHMLASMLSDEEFTEKYIRINRERLRRRYDTIVEGLKKAGIECLKGNAGLFCWMNLGFLLEKKTKDGELQLWDVILKELNLNISPGSSCHCSEVGWFRVCFANMSENTLEIALKRIHEFMDRRRRF
What is the function of this protein?
1-aminocyclopropane-1-carboxylate synthase (ACS) enzymes catalyze the conversion of S-adenosyl-L-methionine (SAM) into 1-aminocyclopropane-1-carboxylate (ACC), a direct precursor of ethylene.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate synthase 7, ACC synthase 7, S-adenosyl-L-methionine methylthioadenosine-lyase 7.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: PYRG_SPICI
Sequence: MAKYIFVTGGVVSGLGKGITASSIGVLLKASGLNVFMQKFDPYLNVDPGTMSPYQHGEVFVTTDGAETDLDLGHYERFIDENLTKESNITSGRIYKNVIEKERRGEYDGGTVQVVPHVTNEIKKKVYHAASTSKADIIITEIGGTVGDIESLPFIEAIRQVRMEQGRENVIYMHVSLVPYIAASKESKTKPTQHSVRELLSLGIQPDIVVARTEQALDDNVLEKIALFCNIEKSNVLVATDVASILWSHKMYEQNAQIVISKLLNLKSLKTDMSEWKRFVEKINQSQQVIEIKLVGKYIELPDAYLSVSESLRIAGYENKVKIKIDWIKAEDVNKKNDQQLLKNAKGILVPGGFDERGFEGRGFEGKILACQFARENNIPFFGICFGMQAAVIEFARNVCHIQDANSSELTETKNAIIDIIRGKDKTDALGGTLRLGNYKTTFVPNTLAHKLYGKKWGFRTSRHRYEVNNDYREQLAQAGLVFSGLYVEKNLVEVIEIPKYPFYLAAQYHPEFTSRPNKPNPLFNGFVQAVIKNK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: MURG_COLP3
Sequence: MSVNHGQGNKDLAKTLLVMAGGTGGHIFPGIAVADELKAQGWKIHWLGTADRMEAQIVPMHGYDISFINISGLRGKNLLTTLVMPFKLLRSLFQARRVIKTVKPDVVIGMGGYASAPGGLAAWLSKIPLIVHEQNAAAGLSNRLLARIANKVCCAFPNAFVSGIDVEVVGNPLRASIGQQALVSENIDQSHEGSKNILVVGGSLGAQVLNKVMPDSFKDLSESDEKYCIWHQTGDNNQALVTASYKQEYIDTGKVRVTEFITDIAAAYQWADIVICRAGALTVSELAMAATPAIFVPLPHAVDDHQTKNALYLVKRDAAKLLPQAELNNESITSLIIELFDQPQTLADMAKASLSAATSDASQKVAKLCQQLSISNGAKLRNNEEKI
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDK_RHOSU
Sequence: MAIQRTFSIIKPDATKRNLTGAINAKLEAAGLRIVAQKRIHLSKAQAAVFYAVHKERPFYDELCEFMASEPIVVQVLEGEDAIAKNREVMGATNPAEAAEGTIRKEFALSIGENSVHGSDAEDTAKEEIAYFFSGLELVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_SPHAL
Sequence: MTKLSGSDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCNDIIREEIKGGVAARKDGAVPTPLEICQHLDAYVIGQNKAKRVLSVAVHNHYKRLANSGRGEDVELAKSNILLVGPTGSGKTLLAQTLARFLDVPFTMADATTLTEAGYVGEDVENIILKLLQSSDYNVEKAQRGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLMEGTTASVPPQGGRKHPQQEFLQVDTTNILFIAGGAFAGLEKIIGDRLQGKSIGFGAHVAGPDERRAGEVLKQIEPEDLLKFGLIPEFVGRLPVIATLEDLDVDALVKILGEPKNALVKQYKKLFDLEEVALTFTDDALVAVAKKAIERKTGARGLRSIVEAILLDTMFDLPDLTDVVEIVVDKDVVEGRKDPVRVYADKAKEAAGDAA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ATPB_SINMW
Sequence: MAKAATPKETAAAKKPAAPKKAASAKTASATTVVAATGAVGRVTQVIGAVVDVAFEEGQLPKILNALETDNNGNRLVLEVAQHLGENSVRTIAMDSTEGLVRGQKVTDTGAPIAVPVGKETLGRIMNVIGEPVDEAGPLKTSARRAIHQDAPAYVDQSTEAQILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVNKHGGGEGSKAALVYGQMNEPPGARARVALTGLTVAEQFRDEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGQMQERITTTTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRMLDPMVVGEEHYEVARKVQGTLQRYKALQDIIAILGMDELSEEDKIAVARARKIERFLSQPFFVAEVFTGSPGKLVALEDTIKGFKGLVNGEYDHLPEAAFYMVGSIEEAVEKAKKLAAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SCA4_RICAK
Sequence: GGFMSQDHTGYENDEGYESDIDEKTQEQAAPAQPTLDTADDGFSFTPASSTQSTPAISTLSGTISTDDQISDPITKAVREIIIQQQKDEIAEQILKDLAALVDRDLAEQKRKEIEEEKEKDKKLSVFFGNPANREFIDNALEKPELKKKLESIEITGYKNILLTYSAANGYHGGFKPVQWENQISASDLRATVVKNDAGDELCTLNETTVKTKPFTVAKKDGTQVQINSYRAIDFPIKLDKADGSMHLSMVALKADGTKPSKDRAVYFTAHYEEGPNGKPQLKEISSPQPLKFAGDGPDAVAYIEHGGEIYTLAVTRGKYKEMMKEVELHQGQSVDLSQIIAEDLTKVQGRSQETLQPIITPNQELKSSIETPTTTQVPPITPASQPVHTETSQMPQSQQVNPNLFNAATALSCSMQDLLNYVNAGLTKEKDGNTQIDLINEAATAILNNEKEKQANFITLTKNMVNNNALTPDTKVARVNAVLETIKNNQDTPDIEKSKMLEATVAITLNSENLTPKQKQQMLEKAVDVDLSFKDDTSRAVAIDGITGAVIKSNLSTKDKGTMLIAVGDKVNASELSNAEKQQLLGSVLKKGVETKILSPEQQQLMQQNLDKITAEQTKNDNITEVQGILANPAFNTIAKTAAIQKVTTKVLDSPITAEIKGETLESITKIVAESPLNVQDKTDIVKGMGEAIASHRTMAPTKKIAAIESVETGVAKSITDLEDKKLMTKGLVDGIYEDKANPEITSEMMKAVSKGVDNSTAIPEDKQALKDAASEAALDRATQNFTEGLKGQNLDEPKPRDDIYNKAQDIAYALKNVVTTVLDANPEKREVSEEEVMNKTSSILNDISKIAIEKVNNLRAMLSPDSNLKTLEEKKAEATKKVDELVKEFGTKSSTEEQQSFIQANLIDDKTLSKEVRLQTIDKLLQEQAQKRAEAIKNPNVKTEDLRVVSGQSALKPISNDEPDIEKTKMVVGRDRVNIKDNIKIMGALMNARDSI
What are the official names of this protein?
Antigenic heat-stable 120 kDa protein, 120 kDa antigen, Protein PS 120, PS120.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_BACFN
Sequence: MTTKIERRIKIKYRVRNKVSGTAARPRMSVFRSNKQIYVQIIDDLSGKTLAAASSLGMTEKLPKKEVAAKVGEIIAKKAQEAGITTVVFDRNGYLYHGRVKEVADAARNGGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ASTD_SALPA
Sequence: MTLWINGDWITGQGERRRKTNPVSAEILWQGNDANAAQVAEACQAARAAFPRWARQPFTARQAIVQKFAALLEAHKADLTEVIARETGKPRWEAATEVTAMINKIAISIKAYHARTGEQKSELVDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVSALLAGNTLIFKPSELTPWTGETVIKLWERAGLPAGVLNLVQGGRETGQALSSLDDLDGLLFTGSASTGYQLHRQLSGQPEKILALEMGGNNPLIIEDVANIDAAVHLTLQSAFITAGQRCTCARRLLVKQGAQGDAFLARLVDVAGRLQPGRWDDDPQSFIGGLISAQAAQHVMEAWRQREALGGRTLLASRKVKEGTSLLTPGIIELTGVADVPDEEVFGPLLNVWRYAHFDEAIRLANNTRFGLSCGLVSTDRAQFEQLLLEARAGIVNWNKPLTGAASTAPFGGVGASGNHRPSAWYAADYCAWPMASLESPELTLPATLSPGLDFSRREAV
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: GSA_SYNJA
Sequence: MTSTLPTRSFNTSRSRQIFARAQQLMPGGVSSPVRAFKSVGGDPVVFDRVAGAYAWDVDGNQYIDYIGSWGPAIVGHAHPEVIEALRRALEKGTSFGAPCVLENELAERVIEAVPSVEMVRFVNSGTEACMAALRLMRAYTGREKVIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPKAATSATLTAPYNDLEAVKALFEQYPDSIAGVILEPVVGNAGFIPPQPGFLEGLRELTQKYGALLVFDEVMTGFRISYGGVQAKFGVIPDLTTLGKVIGGGLPVGAYGGRREIMEMVAPAGPMYQAGTLSGNPLAMTAGIHTLDILRRPGTYEYLERITEQLATGLLQIAQETGHEMCGGYLPGMFGFFFTAGPVRNYEEAKRSDLQKFARFHRGMLERGVYLAPSQFEAGFTSLAHTEADVERTLEAAREVLRTL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFRA2_BACSU
Sequence: MNEVIKSLTDHRSIRSYTDEPVAQEQLDQIIEAVQSAPSSINGQQVTVITVQDKERKKKISELAGGQPWIDQAPVFLLFCADFNRAKIALEDLHDFKMEITNGLESVLVGAVDAGIALGTATAAAESLGLGTVPIGAVRGNPQELIELLELPKYVFPLSGLVIGHPADRSAKKPRLPQEAVNHQETYLNQDELTSHIQAYDEQMSEYMNKRTNGKETRNWSQSIASYYERLYYPHIREMLEKQGFKVEK
What is the function of this protein?
Reduces FMNH(2) to FMN, with NADH or NADPH as reductant.  It also reduces nitroaromatic compounds, quinones, chromates and azo dyes.  It could supply the reduced form of FMN to luciferase-like protein and contribute to the degradation of aromatic compounds.
What are the official names of this protein?
FMN reductase [NAD(P)H], NAD(P)H-dependent FMN reductase, NAD(P)H-dependent nitro/flavin reductase, NAD(P)H-dependent nitroreductase, NAD(P)H-dependent oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the flavin oxidoreductase frp family.
Protein: PTMM_PENSI
Sequence: MNKDKFHVIIVGGSIAGLTLAHCLHRAGISHVVLEKASEPAPQIGASVGILPNGARVLDQLQLYETIEKYIEPLETATIGYPDGFSFSSSYPKLVNERFGFPIAFLDRQKLLEILYQHYPDKSKIRLAARVISIESSAIDSEVTTEDGTIYKGHLIVGADGVHSRVRSEMWKAAQRIKPGLVTKREQRSMTVEYSCIFGISAPIKGLIVGEQVNAFFDHLTIVTIHGKNGRVYWFLIQKLDRKYIYPECPRFTAKEIGPIASDLKEVKFFKDITFGQLWDSRETASMTVLEENVFDTWYHGRMVLMGDSVHKMTPNIGQGANMAIEDAAVLSSLLSDLLQKQTQPPTNAQIERLLAQYREVRYPRVNSIYKTSRFLVRFQARDGIFNTLFGRYYAPHAGDLPADMASKTIAGGELISWMAYM
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes penitrems (PubMed:25831977).  The geranylgeranyl diphosphate (GGPP) synthase ptmG catalyzes the first step in penitrem biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:25831977).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase ptmC then forms 3-geranylgeranylindole (3-GGI) (PubMed:25831977).  Epoxidation by the FAD-dependent monooxygenase ptmM leads to a epoxidized-GGI that is substrate of the terpene cyclase ptmB for cyclization to yield paspaline (PubMed:25831977).  Paspaline is subsequently converted to 13-desoxypaxilline by the cytochrome P450 monooxygenase ptmP, the latter being then converted to paxilline by the cytochrome P450 monooxygenase ptmQ (PubMed:25831977).  Paxilline is converted to beta-paxitriol via C-10 ketoreduction by the short-chain dehydrogenase ptmH which can be monoprenylated at the C-20 by the indole diterpene prenyltransferase ptmD (PubMed:25831977).  A two-step elimination (acetylation and elimination) process performed by the O-acetyltransferase ptmV and ptmI leads to the production of the prenylated form of penijanthine (PubMed:25831977).  The FAD-linked oxidoreductase ptmO then converts the prenylated form of penijanthine into PC-M5 which is in turn transformed into PC-M4 by the aromatic dimethylallyltransferase ptmE (PubMed:25831977).  Five sequential oxidative transformations performed by the cytochrome P450 monooxygenases ptmK, ptmU, ptmL, ptmN and ptmJ yield the various penitrem compounds.  PtmK, ptmU and ptmM are involved in the formation of the key bicyclic ring of penitrem C via the formation of the intermediates secopenitrem D and penitrem D.  PtmL catalyzes the epoxidation of penitrem D and C to yield penitrem B and F, respectively.  PtmJ catalyzes the last benzylic hydroxylation to convert penitrem B to prenitrem E and penitrem F to penitrem A (PubMed:25831977).
What are the official names of this protein?
FAD-dependent monooxygenase ptmM, Penitrem biosynthesis cluster 1 protein M.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PEPD_BIFLO
Sequence: MACTTILVGKDASYDGSTIIARNEDSANGEFNPKRFIVVKPEEQPREYKSVISHLTITLPDDPLQYTAVPNADLKEGIWGEAGVNEANVAMSATETLTTNERVLGADPFVEYTPAKGDEPEVPGGIGEEDFLTIVLPYVKTAREGVQRLGALLEEFGTYEMNGVAFSDSNEIWWLETVGGHHWIAKRVPDEAYVTMPNQLGIDEFDLEDALGDQEAHMCSEDLAEFIETNHLDLAVENTTPFNPRDAFGSHSDSDHVYNTPRAWYMQRFLNPYDEVWDGPDADHKPTSDDIPWARQPERKVTIEDIKYVLSSHYQGTPFDPYGQLGDERTRHMYRTIGINRQSQLAVMQIRPYRPQASRAIQWMAYGSNPFNTLVPFFPNVDTTPAYLEDTTTRVTSENFYWANRIIAALCDGAFRSTSNAVERYQEKTGAMGHRLVAATDEQIARLGLTAAEEAAQSAAEEEFEADNVDGDVQPMTPDETIAALRNPEVREILAAANQTMADQLKEETEKLLDSVLYTRSMEMKNGFHMSDF
What is the function of this protein?
Hydrolyzes a wide range of dipeptides.  Highest activity against Ala-Gln.
What are the official names of this protein?
Dipeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C69 family.
Protein: CH10_FRATO
Sequence: MNIRPLQDRVLVRRAEEEKKSAGGIILTGNAQEKPSQGEVVAVGNGKKLDNGTTLPMDVKVGDKVLFGKYSGSEVKVGDETLLMMREEDIMGIIA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMM1_VANPO
Sequence: MNNLDNLAGNMSNLTIQGKGNETLISLDEYVNNILPSHLKKIFSDNLRENYQIPREFFESAELSGINNKIDQEIQKYSHLLKGLSNNGQTSFGSYLSNSNSFSGWSFIEGFIIGQFSVIIVLIFFIKFFVFSDGSSSNSSNPKPSLNSRSDRTSFSYKSNSMLSSNFFSSIMKRGGKTHYETDIDSGNTNRLNTILEKVYYDVDTHPSESLDWFNVLIAQTIQQFREEAWQRDNIVHSLNDFLHSKSSEMPSYLDDIKITELDIGDDFPIFSNCKIQYSPNSNKKKLEAKIYIDLNDRLAFGIETKLLVNYPKPRTAVLPVNLTVAIVRFQACLTVSLTNAEDFVPTTKETASSQDDDGYFLMFSFGPEYKMDFDIESLIGARSKLQNIPKISSVIEYHIKKWFVERCVEPRFQCIRLPSMWPRSKNTREEKVDTDDVPLSKAE
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: GDPP1_DANRE
Sequence: MGDCSIFTYTDNDFIGKVCCSGQQNRGRSRFDIALRSGWTEKRNTGLFRYRLDELETRILPGSRGYIAQLNIMRGTERRKPQEILSVRQNFDPKQFNFNKINPKELLFELKRESERKCSVIINVSPLEFGHCLLVPEPEKCFPQVLTHLAVQTGIETVLLSADPGFRVGFNSLGGFASVNHLHLHGYYLNHRLKIESSPAKLVLPNLNLYELVDFPSGFLFYTQGPNLDLVVKAICSLTDVLVDHNIAHNLFLTRGCPPQMEPDTSSSRNGVRVIVWPRLSCFGAKEESAFNVALCELAGHLPFKNRQDYESATEETVQDIIQKYLLPQEETAQLKEHLMKCL
What is the function of this protein?
Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
What are the official names of this protein?
GDP-D-glucose phosphorylase 1.
What is the protein family that this protein belongs to?
Belongs to the GDPGP1 family.
What are the subcellular locations of this protein?
Cytoplasm.