PharMolix/UniProtQA huggingface dataset:
Protein: S38A3_HUMAN
Sequence: MEAPLQTEMVELVPNGKHSEGLLPVITPMAGNQRVEDPARSCMEGKSFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSLSFIIIDWASGTSRHGGNH
What is the function of this protein?
Symporter that cotransports specific neutral amino acids and sodium ions, coupled to an H(+) antiporter activity (PubMed:10823827).  Mainly participates in the glutamate-GABA-glutamine cycle in brain where it transports L-glutamine from astrocytes in the intercellular space for the replenishment of both neurotransmitters glutamate and gamma-aminobutyric acid (GABA) in neurons and also functions as the major influx transporter in ganglion cells mediating the uptake of glutamine (By similarity).  The transport activity is specific for L-glutamine, L-histidine and L-asparagine (PubMed:10823827).  The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+) (By similarity).  The transport is pH dependent, saturable, Li(+) tolerant and functions in both direction depending on the concentration gradients of its substrates and cotransported ions (PubMed:10823827).  Also mediates an amino acid-gated H(+) conductance that is not stoichiometrically coupled to the amino acid transport but which influences the ionic gradients that drive the amino acid transport (By similarity).  In addition, may play a role in nitrogen metabolism, amino acid homeostasis, glucose metabolism and renal ammoniagenesis (By similarity).
What are the official names of this protein?
Sodium-coupled neutral amino acid transporter 3, N-system amino acid transporter 1, Na(+)-coupled neutral amino acid transporter 3, Solute carrier family 38 member 3, System N amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
Protein: LIPB_NOVAD
Sequence: MAASETIEIRRETAQVPYREALDAMASRNAAIAEGTAPELIWLLEHPPVYTAGTSASPDELLDPRFEVVEAGRGGRYTYHGPGQRVGYVLLDLRKRARDVRGFVHALEGWVIETLADFGVESWRAEGRVGIWTRGADGREAKIGAIGVRIRRWVTMHGFSVNLSPDLAHFGGIVPCGIEEFGVTSLAALGREVTPDQWDEALLSHLDGFLARLDTPCPPEAA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_LACP7
Sequence: MKRIVLTGGGTAGHVTPNIALIAGLKEQGYEIHYIGSYEGIERELIEKLGIPYHGISSGKLRRYLDIKNFSDPFKVLKGYREAKKLLKNLDPNVVFSKGGFVAVPVVLAAKKRKIPAIIHESDMTPGLANRLCIPSAAKVCANFPETLNYLPKEKAVLTGTPIRKELFSGNKIKGLDFCGFTANIPVLLIVGGSTGALKVNEAVRNLLPTLLKRFQVIHLCGKGKVDPSFNKHKGYVQYEYIGAELNHLFAAADIVISRAGANAICELLALRKPNILIPLSAAASRGDQILNAESFEHQGYSYVIKEEVLSNETLLQAVNHVFDNQKSYIEAMKNSNQNDAVDKIIGLIEEVRLK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPB_NEOSM
Sequence: MPVSIGKIVRVVGPTVDVKFEDGTLPKIENALTCDNNGKILYLEVAQQLGDGIVRAVAMDSTDGLTRDKVVKDTGKPICVPVGRQTLGRIFNVVGEIIDGGGPVPEPNKVSSIYAEPPRFDMQSTSSEILETGIKVIDLLAPYSKGGKVGLFGGAGVGKTVLIMELINNIAKAYGGFSVFAGVGERTREGNDLYSEMVESGVIDKEHPEKSKVVLVYGQMNEPPGARAKVAMSALTMAEYFRDKEGQDVLFFVDNIFRFTQAGAELSTLLGRIPSAVGYQPTLATDMGRLQERITSTKNGSITSVQAIYVPADDITDPAPATSFAHLDSTTVLSRQVAEAGIYPAVDALASSAQILSPEVLGQEHYEVAQKVKGILQSYKSLQDIIAILGMEELSEEDKLTVYRARKIEKFLSQPFHVAEVFTGQPGKFVSLKDTIAGFKELVEGKCDDMPEAAFYMVGNMNEAREKAISLREK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEXA_LACCB
Sequence: MPTQASQKRWKQILQSIYDAIEDHGYPPTVREIGKSVGLSSSSTVAAYLEKLLAAGLIAKDPAKPRTLEVTSAGRDFIGVQDHGIPIVGTVAAGVPITAIENIDDYFPVPDDLPYAADELFMLRVQGNSMIKIGILDGDQIIVKKQNDAENGQIVVAMTEEDEATVKRFYKEKNGIRLHPENDSMDDMFFPDVTILGIVVSLYRPALV
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ZDHC5_MOUSE
Sequence: MPAESGKRFKPSKYVPVSAAAIFLVGATTLFFAFTCPGLSLNVSPAVPIYNAIMFLFVLANFSMATFMDPGIFPRAEEDEDKEDDFRAPLYKTVEIKGIQVRMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLYVLYHIEELSGVRTAVTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTNGCCNNVSRVLCSSPAPRYLGRPKKEKTIVIRPPFLRPEVSDGQITVKIMDNGIQGELRRTKSKGSLEITESQSADAEPPPPPKPDLSRYTGLRTHLSLATNEDSSLLGKDSPPTPTMYKYRPGYSSSSTSAAMPHSSSAKLSRGDSLKEPTSIADSSRHPSYRSEPSLEPESFRSPTFGKSFHFDPLSSGSRSSSLKSAQGTGFELGQLQSIRSEGTTSTSYKSLANQTRNGSLSYDSLLTPSDSPDFESVQAGPEPDPPLGYTSPFLSARLAQQREAERHPRLLPTGPPHREPSPVRYDNLSRHIVASLQEREKLLRQSPPLAGREEEPGLGDSGIQSTPGSGHAPRTSSSSDDSKRSPLSKTPLGRPAVPRFGKPDGLRSRGLGSPEPGTTAPYLGRSISYSSQKAPSGVSETEEVALQPLLTPKDEVQLKTTYSKSNGQPKSIGSASPGPGQPPLSSPTRGGVKKVSGVGGTTYEISV
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates such as CTNND2, CD36, STAT3 and S1PR1 thus plays a role in various biological processes including cell adhesion, fatty acid uptake, bacterial sensing or cardiac functions (PubMed:21820437, PubMed:22081607).  Plays an important role in the regulation of synapse efficacy by mediating palmitoylation of delta-catenin/CTNND2, thereby increasing synaptic delivery and surface stabilization of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) (PubMed:24562000).  Under basal conditions, remains at the synaptic membrane through FYN-mediated phosphorylation that prevents association with endocytic proteins.  Neuronal activity enhances the internalization and trafficking of DHHC5 from spines to dendritic shafts where it palmitoylates delta-catenin/CTNND2.  Regulates cell adhesion at the plasma membrane by palmitoylating GOLGA7B and DSG2.  Plays a role in innate immune response by mediating the palmitoylation of NOD1 and NOD2 and their proper recruitment to the bacterial entry site and phagosomes.  Participates also in fatty acid uptake by palmitoylating CD36 and thereby targeting it to the plasma membrane (PubMed:30605677).  Upon binding of fatty acids to CD36, gets phosphorylated by LYN leading to inactivation and subsequent CD36 caveolar endocytosis.  Controls oligodendrocyte development by catalyzing STAT3 palmitoylation (PubMed:34724258).
What are the official names of this protein?
Palmitoyltransferase ZDHHC5, Zinc finger DHHC domain-containing protein 5, DHHC-5.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOA_DEIRA
Sequence: MEQKRPQLKARVDGDYGEFVLEPLARGYGVTIGNPIRRILMSSIPGTAVTSVYIEDVLHEFSTIPGVREDVIRLILNLKELVVKFHAPGPKTLTLRAQGEGEVRASAFEVPTDAEIVNPDLVIANLAEDGKLVMEVRVEEGEGYVSADKHATKDRINSIPVDAMFSPVRRVAYHVENTRVGQQTDLDRLILRVWTDGSAGPQEALDKAVEILRDELSVFGNVEPMPALESSYAAATPAAVYDPATATLPASVYDSPRQPDLGSLSINPQPFPTDQDTPRVTLEGLGLTTRVLHSLKEEGIDSVDALCALSDRDLKKVPGIGERSLDEIKQQLAQFGLALRD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: TRPB_STAAC
Sequence: MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEDGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGGGSNAIGTFYPFIKDDVALYGVEAAGQGDDTDKHALAIGKGSPGVLHGTKMYLIQDEDGQVQLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMVERGLAND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: LEXA_MYCLB
Sequence: MSDSTDISGITVDGRLHSMDSGLTERQRTILNVIRASVTSRGYPPSIREIADAVGLTSTSSVAHQLRTLERKGYLRRDPNRPRAVNVRGVEETQAAGPAVLTEVAGSDVLPEPTFVPILGRIAAGSPIFAEGTVEDIFPLPRELVGEGTLFLLKVTGDSMVEAAICDGDWVVVRQQKVADNGDIVAAMIDGEATVKTFKRAGGQVWLIPHNPAFDPIPGNDATVLGKVVTVIRKI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CNDB1_RHIWD
Sequence: MPTIIVTTRDGEELSLEADTGLSLMEVIRDGGADELLALCGGCCSCATCHVKVDPAFLAALPPMSEDESDLLDSSDHRDATSRLSCQITVDDGLAGLRVAIAPED
What is the function of this protein?
Component of the chloroacetanilide N-alkylformylase multicomponent enzyme system involved in the degradation of chloroacetanilide herbicides (N-alkoxyalkyl-N-chloroacetyl-substituted aniline derivatives).  In vitro, functions as an intermediate electron transfer protein.
What are the official names of this protein?
Chloroacetanilide N-alkylformylase 1, ferredoxin component, Ferredoxin CndB1.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
Protein: BETA_BURO1
Sequence: MTTREYDYIICGAGSAGNVLATRLTEDPDVTVLLLEAGGPDYRFDFRTQMPAALAYPLQGRRYNWAYETDPEPHMDNRRMECGRGKGLGGSSLINGMCYIRGNALDYDNWSTHKGLENWTYLDCLPYFKKAETRDVGPNDYHGGSGPVSVTTSKPGVNPLFEAMVDAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPKGRRASTARGYLDQAKVRPNLEIVTHALADRILFDGKRASGVTYLRGSERATAHARREVLVCSGAIASPQLLQRSGVGPGAWLKELDIPVVLDLPGVGQNLQDHLEMYIQYECKEPVSLYPALKWWNQPKIGLEWMLNGTGLGASNHFEAGGFIRTRDDDPWPNIQYHFLPVAINYNGSNAIEMHGFQAHVGSMRSPSRGRVKLRSRDPNDHPSILFNYMAEALDWREFRDAIRATREIMRQPALDRYRGRELNPGADCKSDKELDAFVRARAETAFHPSCSCKMGYDDMAVVDEEGRVHGLDGLRVVDASIMPIITTGNLNAPTIMIAEKIADKIRGRTPLARVDVPYFVANGAPARNVAKAVRQPETV
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: GLPK_COREF
Sequence: MRASKANAYVAAIDQGTTSTRCIIIDDTGAVVSVAAKEHEQILPQQGWVEHDPVEIWDNVRAVVSQAMVAIDITPYEISSVGVTNQRETTVIWDPATGEPVYNAIVWQDTRTNEICRELAGEEGQQKWLDRTGLLINSYPAGPKIKWILDNVEGVRERAEKGELYFGTMDTWLLWNLTGGIRGDDGEEALHVTDVTNASRTLLMDIHTQQWDPELCEALDIPMSLLPEIKPSIGDYRSVRHRGILADVPITGVLGDQQAALFGQGGFKEGDTKNTYGTGLFLVMNTGPELKISEHGLLSTIAYQIEGQDPVYALEGSVSMGGSLVQWLRDSLQMIPTAPAIEEFARQVPDNGGVHIVPAFSGLFAPRWHPEARGVITGLTRFANRNHICRAVLEATAFQTREVVDAMARDAGKELESLRVDGAMVQNELLMQMQADILGIDVIRPGDIETTALGTAFAAGLGSGFFKDFDQIIELISIRQTWTPEMTEAERERAYDAWNEAVTHAYPR
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: TAM_ECO24
Sequence: MSDWNPSLYLHFAAERSRPAVELLARVPLENIKYVADLGCGPGNSTALLHQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPEQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARRME
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTU2_YEAST
Sequence: MTGMESGENLENMEDILARHRKENKDLQNKITGMKKQATKSKRKEVNSKCLDLQDKLKTKQENEIRDWKIANNEVFDAEQEDEVTPEKLLEQLSISRDEKEQQNVPVQQQQQGQTKKRRNRQKERLAKRDAAIAKMKEEAALEASKQPDLKKMEQESIDQLCELKKLKQFDIQPDGHCLFASILDQLKLRHDPKKLDQDMDVMKLRWLSCNYVQEHRDDFIPYLFDEETMKMKDIDEYTKEMEHTAQWGGEIEILALSHVFDCPISILMSGRPIQVYNECGKNPELKLVYYKHSYALGEHYNSLHDS
What are the official names of this protein?
OTU domain-containing protein 2.
Protein: MUTS_GRAFK
Sequence: MAAKKSQKVTPLMQQYNSIKLKYPDAMLLFRVGDFYETFGEDAVKAARILNIVLTNRNNGGERTELAGFPHHSLNTYLPKLVKAGQRVAICDQLEDPKMTKTIVKRGVTELVTPGVAMNDDILNSKSNNFLCAVHFGKKNLGVSFLDVSTGEFLCAQGNTEYIDKLLQNFGPSEILVQKKFKKEFNESFGKDKHCFYLDDWIFKIDYSEETLNAHFQTKSLKGFGIDHLEEGIIASGAVLYYLAETRHHRLQHINSINRIAEEQYVWMDRFTIRNLELYHSTAANAVTLLDVIDKTISPMGGRLLKRWLALPLKDAEMIEKRLQVVDFLIKNPEILANIQDQIREISDLERLISKVATQKISPREVNQLKNSLNAIIPVKELALKCNNEALKIIGDNLHSCDLLREKISESISEDAPVLIQRGGVIASGFSSELDELRGLAFSGKDYLDKMIQRETEKTGISSLKIGSNNVYGYYIEVRNTHKDKVPEEWTRKQTLVNAERYITEELKEYESKILGAEEKILHLEQELFGKLIAWMAEYIDPVQQNARLIARLDCLCSFAQQAQAENYSKPEITDSYGMDIEEGRHPVIEKQLPPGEVYVTNNLHLDREEQQIIMITGPNMSGKSAILRQTALIVLMAQMGSFVPARSAEIGLVDKIFTRVGASDNISMGESTFMVEMNETASILNNISDRSLVLLDEIGRGTSTYDGISIAWAISEYLHEHPAKPKTLFATHYHELNEMCETFERIKNFNVSVKELKDNVLFLRKLVPGGSEHSFGIHVAKMAGMPQMVLHRANKILAKLEASHSMEDSGAVLKKSAEDEMQLSFFNLDDPLLEDLKQELLGIDIDTLTPVEALMKLNEIKRMLGNNKQQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RIMM_FRAAA
Sequence: MTEPIVVGRIGRPHGVRGDVTIEVRTDLPQRRFALGAVLGREGGGAPLTVAEARWHSGRLLLRFQGVEDRGAAEALRDVLLTIDSAEAGPPVDDDEDAEGEGGDIWWDRDLVGLEAVTTAGATLGRVTDVIHAPAGDLLAVGRPGGGEHLVPFVREIVPTVDPAAGRIVVDPPPGLLDLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_YERPA
Sequence: MYTKILGTGSYLPVQVRSNADLEKMVDTSDEWIVTRTGIRERRIAGLDETVATMGFQAAEKALEMAGIDKDDIGLIIVATTSSSHAFPSSACQVQRMLGIKDAASFDLAAACAGFTYALSVADQYVKSGAVKHAIVIGSDVLSRALDPEDRGTIILFGDGAGAVVLGASEQPGIMSTHLHADGRYGELLALPYPDRQQDQPAYVTMAGNEVFKVAVTELAHIVDETLQANNLDRTALDWLVPHQANLRIISATAKKLGMGMDKVVITLDRHGNTSAASVPSAFDEAVRDGRIQRGQLVLLEAFGGGFTWGSALVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_SYNPW
Sequence: MHLSDLAHPNELHGLSVAELQDVAKQIRERHLEVVSNSGGHLGPGLGVVELTLALYQTLDLDKDRVVWDVGHQAYPHKLITGRYADFDSLRQQGGVAGYLKRCESEFDHFGAGHASTSISAALGMAMARDRQGLDYKCVAVIGDGALTGGMALEAINHAGHMPNTPLLVVLNDNDMSISPPVGALSSHLNRMRLSPPMQFLSGSVEESMRHLPFMGGDLPPELNRLKESMRRLAVPKVGAVFEELGFTYMGPIDGHDMGEMIRTFQAAHRIGGPALVHVITKKGKGYPYAEADQVGYHAQSAFDLGTGKARPSKTPKPPSYSKVFGQTLVKICEQNSKVVGITAAMATGTGLDLLQKALPDQYVDVGIAEQHAVTLAAGMACDGLRPVVAIYSTFLQRAFDQMIHDVGIQNLPVTFVLDRAGIVGADGPTHQGQYDISYLRAIPNFTVMAPKDEAELQRMLVSSLQHSGPCAIRIPRGPGEGVPLMEEGWEPLPIGRGEVLRDGDDLLIVAYGAMNSKALATADLLASCGVQSTVVNARFLRPLDDELLHPLARRIGKVVTIEEGTLAGGFGSALTESLLDADIKPSILRLGIPDVLVDHATPQQSFEKLGLTPAQMAESIQGFLQRSKLTTATSVVQQPSVSVLES
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PESC_AJECN
Sequence: MAGRLREERKYRQKNRGLVQERIRLSLVVWESRKQGTSGQAKNFITRTQAVRKLQISLPDFRRLCIFKGIYPREPRNKKKASKAATPSTTFYYTRDIQYLLHEPLLKKFREQKALSKKIARALGRGEVGNAARLEKNNAPKLSLDHIIKERYPTFIDALRDLDDALSLLFLFANLPSTTSVPAKTITLCQRLCHEFQHYLIATNSLRKSFLSIKGIYYQATILGQDIMWLVPYRFVQRVTGDVDYRIMGTFVEFYTTLLGFVNYKLYTSIGLVYPPKFDKSSDERGAELAAFTLEGRYFGEAHKAIETSRQPNGSAEKAATTSKELQAKVDNILEKTQLDTDPTDQSTEDQEENIEAIDKFEPIAPEADSLPQPQISGDEAGSLFATFTFYISREAPRAPLEFLLRSFGCKRIGWDSVLGDGAFTHDELDARITHQIVDRPQLPQASLPPLPKNPEDGTEAAPRPGTRVPGRTYIQPQWVWDCINEGKLLRPDLYAPGATLPPHLSPWVKPSERGYDPRASLADQEEEGEAERAAEAEEYENDEQEESGEESTKSKQSKELLANLARDSGDENTSGDESVNGGMDIAMAEDTDESSDDGDGADKFEGFDQDEDMSSESEDEEEKARSQHQKELEAEAAGLPFSASSQAESGTIRGKKQQAPLAKKRAAQKKKEEEELERQKMMMSRKKRKLLDKMIYSNKKQDAEAEKLRQKRRKIEQGLNKK
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Pescadillo homolog, Nucleolar protein 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: GATY_SHIBS
Sequence: MHVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATEPRDYLQSAKSAMRDVVSKVIADCGCEGRA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: PRF2_ARATH
Sequence: MSWQSYVDDHLMCEVEGNHLTHAAIFGQDGSVWAQSSAFPQLKPAEIAGINKDFEEAGHLAPTGLFLGGEKYMVVQGEAGAVIRGKKGPGGVTIKKTTQALVFGIYDEPMTGGQCNLVVERLGDYLIESGL
What is the function of this protein?
Binds to actin monomers and regulates the organization of the actin cytoskeleton (PubMed:21090759).  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (PubMed:26996265, PubMed:16313636, PubMed:29861135).  At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate (PubMed:29861135).  Binds G-actin and poly-L-proline with low affinity in vitro (PubMed:19200149).  Binds ACT1, ACT7 and ACT11 and inhibits actin polymerization (PubMed:26578694).  May be involved in the cross-talk between vesicular trafficking and the actin cytoskeleton (PubMed:21090759).  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).  Inhibits cell growth of various pathogenic fungal strains (PubMed:30056100).  May play a role as antifungal proteins in the defense system against fungal pathogen attacks (PubMed:30056100).
What are the official names of this protein?
Profilin-2, AtPROF2, AthPRF2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Endoplasmic reticulum. Cytoplasm, cytosol. Nucleus.