PharMolix/UniProtQA huggingface dataset:
Protein: CAIB_SALPK
Sequence: MNHLPMPTFGPLAGVRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWEHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGMTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEICPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQINECFKDIGLAHILGTPEVPEGTQLIHRVECPYGPLVEEKLDAWLATHTIAEVQARFAELNIACAKVLTIPELEGNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGKIWRGMPSHGMDTAAILKNIGYSEADIKELVGKGLAKVED
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_BLOFL
Sequence: MAKYVGPKLKLSRRENTDLFLKSGIRSIDSKCQFDHAPGQHSIRKSRLSDYGVQLREKQKVKRMYGILENQFANYYRKSASMKGNTGEILLQLLESRLDNVVYRMGFGSTRAESRQLVSHKSIIVNDCIVNIASYQVVPNTVIQVYKKSHNQSRIYAALEIAEQQRESVPWIEVDSAKLKGIFKRRPERSELSANINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TRMD_CLAM3
Sequence: MRIDIVSIFPEFFGVLDISLLGRARQSGLIDLRVHDLRAFTHDRHRTVDDTPYGGGAGMVMRPEPWGEAMDEVLADDTDPVVIFPSPAGEVFTQAMAQELSAEPHLAFGCGRYEGIDQRVVDHTATRARVRLVSLGDYVLNGGEVAVMAMIEAIGRLVPGVVGNPASLVEESHSEGLLEHPSYTKPPEWRGLAVPDVLRSGNHAAIAAWRREQQLERTRRVRPDLLPE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STT3A_ORYSJ
Sequence: MAEPESSTAAAGGSRLRNACGGVLCAFTLLLIGVLAFSIRLFSVIKYESVIHEFDPYFNFRVTQFLSKNGIYEFWNWFDDRTWYPLGRVIGGTVYPGLTLTAGTIWWLLNSLNIPLSVETVCVFTAPIFSANASWATYLLTKEAKGTGAGLMAAAILAMVPSYISRSVAGSYDNEAVAIFALIFTFYLYVKTLNTGSLFYATLNALSYFYMVCSWGGYTFIINLIPIHVLLCIVTGRYSSRLYIAYAPLVILGTLLAALVPVVGFNAVMTSEHFASFLVFIILHVVALVYYIKGLLTPRLFKVAMTLVITVGLAVCFAVIAILIALVASSPTKGWSGRSLSLLDPTYASKYIPIIASVSEHQPPTWPSYFMDINVLAFLIPAGIISCFLPLSDASSFVVLYLVTAVYFSGVMVRLMLVLAPAACILSGIALSEAFDVLTRSVKYQLSKLFDDSPAASGDSSAESSSASTVSTNSAKNETRPEKTETAPKEKPSKKNRKKEKEVAESVPVKPKKEKKLLVLPMEASVLGILLLIVLGGFYVVHCVWAAAEAYSAPSIVLTSRSRDGLHVFDDFREAYAWLSHNTDVDDKVASWWDYGYQTTAMANRTVIVDNNTWNNTHIATVGTAMSSPEKAAWEIFNSLDVKYVLVVFGGLVGYPSDDINKFLWMVRIGGGVFPHIKEPDYLRDGNYRVDAQGTPTMLNCLMYKLCYYRFVETDGKGFDRVRGYEIGKKHFKLTHFEEVFTTHHWMVRIYKLKPQKNRVRGKLKKLKSGSKASSTNAAGRKKNPWQ
What is the function of this protein?
Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.  This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A, Oligosaccharyl transferase subunit STT3A, STT3-A, Protein STAUROSPORIN AND TEMPERATURE SENSITIVE 3-LIKE A.
What is the protein family that this protein belongs to?
Belongs to the STT3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: THYN1_CHICK
Sequence: MPWPSRKRDKGAVADKKEPDAKIAKTEEETEDKEEEEKSTKPPAGSSKSGLKNWKKAKESDSGGEESKITYCHWLLKSEPESRLEKGVDVKFSIEDLKAQPNQTTFWEGVRNYQARNFLRAMKLGQQAFFYHSNCKEPGIVGIVKIVKEAYPDHTQFDQKDPHYDSSSRKENPKWSMVDVQFVRMTKRFIPLSEIKTHHLAHKADGGPLKNMMLFSRQRLSIQPLTQEEFDFVLSLEEEKPH
What is the function of this protein?
Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
What are the official names of this protein?
Thymocyte nuclear protein 1, Thymocyte protein Thy28, cThy28.
What are the subcellular locations of this protein?
Nucleus.
Protein: P2C19_ORYSJ
Sequence: MDAGGEEEKQERHRVDGASPSMVALRSDVLHAVLGGKSHNQDTSELVTLSEWSKNKFPLYAYAAAFMFLVMQEYDKRSHGIDFLNRDFVVRDLGMPSLNKHFPVKEFYCSYRRKSGHSTYTYGFFMLQKLILIQNAHIRREEEEEGACSMVTTSHRTGHSRSVGLAARDDPTAEMRLVQGEGSVGTTSHRMGALLERWISREGRTDGGDTSVQGERSVGTTSHRMGALLDVGSAVDDPAKQRSAMGNSLPVESKFTDEKENDRIKYVVSSMQGWGEKMEDAHAAILNLDDTMTSFFGVYDGHGGAEVASYCAKRFHIELCNHEDYDSNLSNAMRSAFYSMDEDLQLSDAWRELVIPRNNGWMYFLKAAACTSICKATYTEPAYEGSTACVVVIRGNQLIVGHAGDSRCVLSRNGQASALSVDHKPDRDFACKKNERLPPEDQMLTCNPDILTMDITDDMEFLVIATEGLWCNMTNQNVVDHTHDRLLEGAEARVICEELVQFGLPSGDNTTVILVLFKPGAYPAVPPVDTDTDTDSHTGDDVDNNDPANEVDPTANAGSDDSNTSDEVKVDATATAVGSSSTTAVAADEATVVSLSTATITIVDNYFFINTSEEVDPTANAGSDDSNTGDEVKVDATASSGLSDWELIYSEF
What are the official names of this protein?
Probable protein phosphatase 2C 19, OsPP2C19.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: SYE_CLOBL
Sequence: MTNKVRTRFAPSPTGYMHVGNLRTALYAYLIAKHDNGDFILRIEDTDQERLVEGALDVIYNTLKITGLSHDEGPDIGGPVGPYVQSERRNIYIEYAEKLIEKGEAYYCFCSKERLDMLRANSEALKRPFRYDKHCIDLSKEEIDKKIAEGVPYVIRQKNPTTGSTSFHDEIYGDISVDNSELDDMILIKSDGLPTYNFANVVDDHLMGITHVVRGSEYLSSSPKYNRLYEAFGWDVPIYVHCPPIMKDEHHKLSKRNGDASFEDLMAKGYLKEAILNYIALLGWNPGGEKEVFSMEELIEAFNYRNINKAPAVFDTKKLKWMNGEYIRALSLDKFHEMALPYYEEALTRDLDTKKISELLHTRVEVLNEIPEQLDFFNNLLEYSPEMYIHKKMKTTYENSLKSLEEVLPKLEALENWTFENIKEVCMNLVKELEVKNGVVLWPIRTAVSGKQFTPGGAFEIADILGKEETLERIKIGIDKLKALQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCSB_STAA3
Sequence: MTHNIHDNISQWMKSNEETPIVMSSRIRLARNLENHVHPLMYATENDGFRVINEVQDALPNFELMRLDQMDQQSKMKMVAKHLISPELIKQPAAAVLVNDDESLSVMINEEDHIRIQAMGTDTTLQALYNQASSIDDELDRSLDISYDEQLGYLTTCPTNIGTGMRASVMLHLPGLSIMKRMTRIAQTINRFGYTIRGIYGEGSQVYGHTYQVSNQLTLGKSELEIIETLTEVVNQIIHEEKQIRQKLDTYNQLETQDRVFRSLGILQNCRMITMEEASYRLSEVKLGIDLNYIELQNFKFNELMVAIQSPFLLDEEDDKSVKEKRADILREHIK
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in proteins.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: PYRI_SALTI
Sequence: MTHDNKLQVEAIKCGTVIDHIPAQVGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLTDEQVNQLALYAPQATVNRIDNYDVVGKSRPSLPERINNVLVCPNSNCISHAEPVSSSFAVKKRANDIALKCKYCEKEFSHNVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: Y2666_PECAS
Sequence: MQLSTTPNLEGFTITEYCGVVTGEAILGANIFRDFFASIRDVVGGRSGAYEKELRKARQIAFKELQEQAEDLGANAIVGIDLDYETVGKDGSMLMVTVSGTAVKVRR
What are the official names of this protein?
UPF0145 protein ECA2666.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: TRI15_MACMU
Sequence: MPSTPSLKVVHELPACTLCVGPLEDAVTAPCGHTFCRLCLPTLSQMGAQSSGKILLCPLCQEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSMERDEIEDVKCREDQKLQVLLTQIENKKHQVEAAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVSRLGAQVKELEEKCQQPASELLQDIRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKNLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRYVGVALDYEAGQVTLFNAQTQEPIFTFAASFSGKVFPFFAVWKKGSCLTLKG
What is the function of this protein?
E3 ubiquitin ligase that plays a role in several processes including innate antiviral immnity, cell migration and chemotaxis.  Acts as a 'Lys-63'-specific ubiquitin ligase for MAPK1/ERK2 and MAPK3/ERK1, promoting their activation by facilitating their interaction with MAP2K1 and MAP2K2.  Plays also a role in cell migration and chemotaxis by acting as a stable focal adhesion component upon recruitment by multi-adapter protein paxillin/PXN.  Functions in the RIGI-mediated interferon induction pathway upstream or at the level of MAVS.  Inhibits NF-kappa-B activation by turnover of 'Lys-63'-linked ubiquitination of MAP3K7/TAK1.  Mechanistically, prevents TRIM8 cytoplasmic translocation and thus inhibits TRIM8-mediated 'Lys-63'-linked polyubiquitination of MAP3K7/TAK1 in the cytoplasm.  Plays also an important regulatory effect on the activation of hepatic stellate cells (HSCs).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM15.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: PGKB_CRIFA
Sequence: MSLAPKKTIDDAVVKGKKVLIRVDFNVPVKNGEITNDFRIRSALPTIQKVLKEGGSCILMSHLGRPKGAKMSDPKPAKSVRGYEEAATLRPVAARLSELLGQKVEFAPDCLDAASYAAKLKGGDVLLLENVRFYAEEGSKKEEERDAMAKVLAAYGDVYVSDAFGTAHRDSADMTGIPKVLGAGYAGYLMEKEINYFAQVLNNPPRPLVAIVGGAKVSDKIQLLDNMLGRINYLVIGGAMAYTFQKAQGHAIGISMCEEDKLDLAKSLLKKAQERNVEVLLPVDHVCNKEFQGVDAPLVTKDVEIPEGYMALDIGPKTIKIYEDVIAKCKSTIWNGPMGVFEMPCYSKGTFAVAKAMGNGTQKNGLMSIIGGGDTASAAELSGEAKNMSHVSTGGGASLELLEGKSLPGVTVLTNKE
What are the official names of this protein?
Phosphoglycerate kinase, cytosolic, Phosphoglycerate kinase B.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_PSYIN
Sequence: MDKRFQLVSQFSPAGDQPQAIEQLINGLKSGLAFQTLLGVTGSGKTFTLANAIAKLNRPTLILAPNKTLAAQLYGEMKEFFPNNAVEYFVSYYDYYQPEAYVPSSDSFIEKDAAINAHIEQMRLSATKALLERKDVVLVASVSAIYGLGDPTAYLQMMLHLTVGEIISSREILQRLVDLQYNRNETELSRGTFRVRGEVIDIFPADSEKEALRIELFDDEVEQISVFDPLTGQGIDKLARVTVYPKTHYVTPREQILKAVDAIKVELNERKKEFLEQNKLLEEQRISQRTLYDIEMMNELGYCSGIENYSRYLSGRSEGQAPPTLFDYLPKDALLIIDESHVTVPQIGAMYKGDRSRKENLVNYGFRLPSALDNRPLKFAEFEKIAPQTIYVSATPSDYEINKSQGEIIRQVIRPTGLLDPVIEVRPVTTQVDDLLSEINIRLPLKERVLVTTLTKRMAEDLTDYLHEHGIKARYLHSDVNTVERVEIIRDLRLGIFDVLIGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTMGRAARNLNGKAILYAARITGSMQKAIKVTEDRRELQNKFNIENGIIPQGLSKQVNDVMQLGQKNLKKGNLKQGKVAEYKANYQIHSEQDILKQIALSEKQMFACAKNLEFEKAALFRDEVTKLHEQLVSIG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQ13_SCHPO
Sequence: MHINEETDWIDLVKPALAKKPKKIVDNSDKFPTPRGFQQKSLVSKNIHSGNSASSTSIFAKREEELQKDLLLKKAWELAYSPLKQIPMNAILAYMSGNSLQIFSIMTTLMLLVNPLKAITSTGSAFTPFKGTHPGTLWPAMGAYILFQLLLMGIGVYKLQRMGLLPTTTSDWLAWEVSKVFMDRSYGPSKTVL
What are the official names of this protein?
ER membrane protein complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the EMC4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PPR3D_HUMAN
Sequence: MSRGPSSAVLPSALGSRKLGPRSLSCLSDLDGGVALEPRACRPPGSPGRAPPPTPAPSGCDPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQKLRVRFADALGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPPPVEAADFGERLQRQLVCLERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRSTHEAVARWRGPAGPEGTEDVFTFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSLTCRNHALHMPRGECEESWIHFI
What is the function of this protein?
Seems to act as a glycogen-targeting subunit for PP1.  PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 3D, Protein phosphatase 1 regulatory subunit 6, PP1 subunit R6, Protein phosphatase 1-binding subunit R6.
Protein: PAAH_ECOLI
Sequence: MMINVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQDVNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVYDWRAEREAVVGLEAVSDSFSPMKVEKKSDGVTEIDDVLLIETQGETAQALAIRLARPVVVIDKMAGKVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQHHYGEERYRPCSLLRQRALLESGYES
What is the function of this protein?
Catalyzes the oxidation of 3-hydroxyadipyl-CoA to yield 3-oxoadipyl-CoA.
What are the official names of this protein?
3-hydroxyadipyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: CHLL_NEOYE
Sequence: MKLAVYGKGGIGKSTTSCNISVALSKRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLQSKDYHYEDVWPEDVIYKGYGGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFDEYDIILFDVLGDVVCGGFAAPLNYADYCLIITDNGFDALFAANRIAASVREKARTHSLRLAGLVGNRTDKRDLIDKYIDCVPMPVLEVLPLIEDIRVSRVKGKTLFEMAEIDKDLAYVCDYYLNIADQLITRPEGVVPKESPDRELFSLLSDFYLNPKSKVGQEKVDQEELDLMIV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BSPH1_MOUSE
Sequence: MAQPLDFLLVSICLFHSLFSFQVEDYYAPTIESLIRNPETEDGACVFPFLYRSEIFYDCVNFNLKHKWCSLNKTYQGYWKYCALSDYAPCAFPFWYRHMIYWDCTEDGEVFGKKWCSLTPNYNKDQVWKYCIE
What is the function of this protein?
Binds sperm in vitro and promotes sperm capacitation (PubMed:22539676, PubMed:24307707).  Specifically promotes capacitation induced by high density lipoproteins (HDLs) (PubMed:25602034).  Also binds heparin, phospholipid liposomes, and weakly to gelatin (PubMed:22539676).  Does not bind chondroitin sulfate B (PubMed:22539676).
What are the official names of this protein?
Binder of sperm protein homolog 1, Bovine seminal plasma protein homolog 1, Bovine seminal plasma protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the seminal plasma protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLME_STRM5
Sequence: MATRSKSSQRWLKEHFSDPFVKKAQAEGMRSRAAYKLEELLERDRLLKPHMVVVDLGAAPGGWSQQVRRQIGDTGRVLALDILDMPPLAGVEFLHGDFREETVLSQFEAMLGDQPVDLVLSDMAPNKSGVGAVDQPRMMHLAELALDFADNHLKTGGAFLIKLFQGEGFDDYVRDMRRRYDKVSIRKPEASRKRSPEVYALGQGKRAHMK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2441_BACCZ
Sequence: MNDLRYPIGQFTYKRPITEEMIDTWIQEIEDLPNELTKAIKDLDQKQLDTPYRVGGWTVRQVVHHVVDSHMNSYIRFKLALTEKNPTIKPYKEEKWAELPDSKLPVDVSLVMLDSLHKRWVNLLYSLELEDLEKTFNHPDTGETKLAAAIGLYAWHGRHHTAHITSLRKRLNW
What is the function of this protein?
Possible metal-dependent hydrolase.
What are the official names of this protein?
Putative metal-dependent hydrolase BCE33L2441.
What is the protein family that this protein belongs to?
Belongs to the metal hydrolase YfiT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURO_HALLT
Sequence: MYVGRFVVVAPGIGAYRVSSRSFPNRRVTDRDGRLTVGPTPDAPETDNPYVSYNCARAVRTPTDEPLAVVGNGSHVDPIAEKLELGYPARDALATPLLALDFEKDDYDTPRIAGVVGAETATIGVVRRDGLVVEAVDEPTIVATYETDSPEPYALAAADAETPDAAAAATEVLGADFEHPVCAAGATVDADGATLAFDNDAE
What is the function of this protein?
Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.
What are the official names of this protein?
IMP cyclohydrolase, IMP synthase, Inosinicase.
What is the protein family that this protein belongs to?
Belongs to the archaeal IMP cyclohydrolase family.
Protein: SYE_DICT6
Sequence: MDNVRVRIAPSPTGYLHVGTAHTALFNWLFARHNKGTFILRIEDTDLARSTKEYEENIIEGLKWLGLYWDEGPYYQTQRLDLYRKYADELLKKGLAYYCYCTPEELEERRKEALAQKKPPRYDRKCLYLSDEERARYEREGRKPAIRLLVPEGKTVFNDIIRGEIEFNNEDIGDFVIMKSDGIPTYNFAVVIDDYTMGITHVIRGEDHISNTPKQLFIYNAFGWTPPEFAHLPLLLGPDRSKLSKRHGVTSVTEYKKMGYLPQALVNYLALLGWTPEENREIYTVEELIELFDLRRVTKNPGIFDVTKLEWINTQHIRRLSLEELADLTYPFLKEAEWFKEENFNKEYYLKVLSLLQERLKTLAQIKEYADYFFVDDLDYDVETVKKVCKHPDTPLYLEKIKDVWSQLSEFTAENLEASLKKLAEENQIPTKNLVHPIRVALTNKTVGPGLYEIAEVLGKEKTLKRLEKFIQFLKTL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_SHIFL
Sequence: MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLGGNQLEVRFPEHPHPLFVIAESGFGTGLNFLTLWKAFDQFREAHPQAQLQRLHFISFEKFPLTRADLALAHQHWPELAPWAEQLQAQWPMPLPGCHRLLLDESRVTLDLWFGDINELTSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRRGLQEAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSTPWFNRTGSSKREVAIIGGGIASALLSLALLRRGWQVALYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFARRFYDQLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVATNCSGITYPQGGWLCPAELTRNVLELAQQQGLQIYYQYQLQNLSRKDDCWLLNFAGDQQATHSVVVLANGHQISRFSQTSTLPVYSVAGQVSHIPTTPELAELKQVLCYDGYLTPQNPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDVSDKEARCGVRCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALGSRGLCSAPLCAEILAAQMSDEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D1CYA_RANDY
Sequence: MFTLKKSLLLLFFLGTINFSLCEEERNAEEERRDYPEERDVEVEKRIIPLPLGYFAKKT
What is the function of this protein?
Antimicrobial peptide.  Has activity against the Gram-positive bacterium S. aureus (MIC=6 uM) and the Gram-negative bacterium E. coli (MIC=3 uM).  Lacks hemolytic activity against human erythrocytes.
What are the official names of this protein?
Dybowskin-1CDYa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: CH60_EHRRG
Sequence: MANMVVTGEQLDKSIREVVRILEDAVGCTAGPKGLTVAISKPYGAPEVTKDGYKVMKSIKPEDPLALAIANIIAQSASQCNDKVGDGTTTCSILTAKVIEEVSKVKAAGADIICVREGVLKAKEAVLEALKCMKREVLSEEEIAQVATISANGDKNIGTKIAQCVKEVGKDGVITVEESKGFKELDVEKTDGMQFDRGYLSPYFVTNSEKMLVEFENPYILLTEKKLNIIQPLLPILENIARSGRPLLIIAEDVEGEALSTLVLNKLRGGLHVAAVKAPGFGDRRKDMLGDIAILTGAKHVINDELAIKMEDLTLCDLGTAKNIRITKDTTTIIGSVDNSCAHVQSRICQIRMQIDNSTSDYDKEKLQERLAKLSGGVAVLKVGGSSEVEVKERKDRVEDALHATRAAVEEGVVPGGGAALLYTLSALDNLKSKNDDEQLGINIVKRALQAPIKRIIKNAGSENAPCVIAHLLKQNDKELIFNVDVMNFANAFTSGVIDPLKVVRIAFDFAVSLAAVFMTLNAIVVDIPSKDDNSAAGGAGMGGMGGMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y638_METJA
Sequence: MKEVKDFYDKWEPEDFPNYIKLLMNFADELIFEEISLLLKKFENKKDFLVLDCGCGFGAFYNLTKDFNTIYLDISLNLLKRFKLKERKICANILHLPFKDNTFDLVLCINVLEHVNYLKALNEIRRILKNKGKLIVVVVNKDSLIKEEIFNDFKIFHKPLSIKDFEIDGFKIVYSNSVYFLPSIFKISPPIILSKIIEYWKPVDKKLSKIFKNKGQFLIIEMVKE
What are the official names of this protein?
Uncharacterized protein MJ0638.
Protein: ATPB_BRUC2
Sequence: MAKAATPKTTAAAEAKPAAKAPAKKAAPKTTAAAKPAATKSGAPKAAAAGAIGHITQVIGAVVDVKFPEGQLPLILNALEVDNQGHRLVLEVAQHLGEDTVRTIAMDATEGLVRGQEARDTGEPIMVPVGVETLGRIMNVIGEPVDEAGPIKTKATRAIHQNAPEYIEQSTEAEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVNKLGGGEGSKAALVYGQMNEPPGARARVALSGLTVAENFRDQGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAMQERITTTTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRMLDPKVVGEEHYAVARQVQSILQRYKALQDIIAILGMDELSEEDKLTVARARKIERFLSQPFFVAEVFTGSPGKLVDLADTIKGFKGLCAGDYDHLPEAAFYMVGSIEEALEKAKKLAAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.