PharMolix/UniProtQA huggingface dataset:
Protein: LRC8E_XENTR
Sequence: MIPVAEFKQFTEQQPAFKVLKPWWDVLAEYITYAMLMIGVFGCTLQVTQDKIICLPNHTSADVVSQITCQEYDQQSPPSNDSDLETTIPPPTATSSPPREMSGLRNNLDLQQYSFINQMCYETALHWYAKYFPYLVVIHTLIFIICGNFWFKFPGTSSKIEHFISILGKCFDSPWTTRALSEVSGESSQEKPSQERSIDRELSKPNFEEGSPATADLPIAEKLVAETSSASVLDKKEGEQAKALFEKVKKFRHHVEEGDLLYSMYMRQTVLKVCKFVLITIYNAVLVGKIHFIVPCSVHTEDMTGYNSFCCNHTKAHLFSKLAITYLCFLGVYGLTCLYTLYWLFRRPLKEYSFRSVREETGIGDIPDVKNDFAFVLHLVDQYDSLYSKRFAVFLSEVSESRLRQLNLNHEWPADKLRQKLQHTPEGRLELHLFKLPGLPDTVFEVAEMESLKLEMVNEALIPPLVSKLVRLEELSLINCTAKVQHASLAYLRDHLRILQVKFDDIKEIPLWIFSLRALEELHLFGWLSQDLSKNPALESLRELKSLKVLTIKSNLSKIPATVADVAGHLQKFSIHNDGTKLLTLNALKRLALVKELELVRCELERIPHAVFSLTNLQVLDLKENTLHTIEEIISLQHCRKLSVLRLWHNQIAYIPEHIRKLKGLEELSLNRNKILVIPSQLFLCNKLRHLDLSNNEIRELPPEIGVLQLLQYLGLSGNFLEDLPNELFFCQKLKTLKLGQNRLGNLSPKVGSLVCLVKLELKGNRMDTLPPELGNCVSLKRSGLTVEPSLFETLPVEVRDKLKED
What is the function of this protein?
Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes.  The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine.  Mediates efflux of amino acids, such as aspartate, in response to osmotic stress.  The VRAC channel also mediates transport of immunoreactive cyclic dinucleotide GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response to DNA virus in the cytosol.  Channel activity requires lrrc8a plus at least one other family member (lrrc8b, lrrc8c, lrrc8d or lrrc8e); channel characteristics depend on the precise subunit composition.  Also plays a role in lysosome homeostasis by forming functional lysosomal VRAC channels in response to low cytoplasmic ionic strength condition: lysosomal VRAC channels are necessary for the formation of large lysosome-derived vacuoles, which store and then expel excess water to maintain cytosolic water homeostasis.
What are the official names of this protein?
Volume-regulated anion channel subunit LRRC8E, Leucine-rich repeat-containing protein 8E.
What is the protein family that this protein belongs to?
Belongs to the LRRC8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. Lysosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=In the absence of lrrc8a, resides primarily in the endoplasmic reticulum. Requires lrrc8a for localization at the cell membrane or lysosome membrane.
Protein: Y1144_MYCTO
Sequence: MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVVVDLRGDDVVGGLGDRARFAQADVTDEAAVSNALELADSLGPVRVVVNCAGTGNAIRVLSRDGVFPLAAFRKIVDINLVGTFNVLRLGAERIAKTEPIGEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIARDLASKLIRVVTIAPGLFDTPLLASLPAEAKASLGQQVPHPSRLGNPDEYGALVLHIIENPMLNGEVIRLDGAIRMAPR
What are the official names of this protein?
Uncharacterized oxidoreductase MT1177.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RLME_CELJU
Sequence: MARSKSSNRWLEEHFSDQYVKKSHADGYRTRASYKLLELNDKDRLIRPGMLVVDLGAAPGGWSQVAGQQVGTHGRVVASDILPMDTLEGVEFIQGDFTDDSVFNQILLAIGDTPVDLVISDMAPNMSGINAVDQPQAMYLVELALDMAKRVLKPQGNFVAKVFHGEGYDQYLKDLKGCFEKVVIRKPDASRSRSREVYVVGKGFLGCQTVS
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MKAR_SCLS1
Sequence: MILDTILSHVPKVVLTGLAGIGAFIVAGKVISYIRLLLSLFVLSGKNLRTYGKKGTWAVVTGASDGLGKEYAIQLAQKGFNIVLISRTESKLQTLASEIQTKYAGSNIQTKILAMDFAANRDEDYAKLKALVDGLDVGILVNNVGQSHSIPVPFIQTPKEEMRDIITINCIGTLRVTQIVAPGMVQRKRGLILTMGSFGGWLPTPLLATYSGSKAFLQQWSTSLGGELEGTGVDVELVLSYLVTTAMSKIRRTSLFIPNPRTFVKTTLAKVGRSGGAQKIAYTSTPFWGHALMQWWLENTLGVGGSFVVNQNKVMHQSIRARALKKAERDAKKA
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: UREA2_CANEN
Sequence: MKLSPREVEKISLHNAGFLAQKRLARGVRLNYSESVALIASQILEHARDGEKTVAQLMSIGKHLLGRRQVLPAVPHLLNIIQVEATLPNGTKLVTVHDPIANENGDLEEALYGSFLPVPSLDKFAESKEEHKIPGEIICADGRLTLNPGRKAVFLKVVNHGDRPIQVGSHYHFIEVNPYLTFDRRKAYGMRLNIAAGDSVRFEPGDHKTVNLVSIGGNKIIRGGNAIADGPVNEANCKAAMEIVCRREFGHKEEEDASEGVTTGDPDCPFTKAIPREEYANKYGPTIGDKIRLGDTDLIAEIEKDFALYGDESVFGGGKVIRDGMGQSSGHPPAMSLDTVITSAVIIDYTGIIKADIGIKDGLIASIGKAGNPDIMNGVFPNMIIGVNTEVICGEGLIVTAGGIDCHVHYICPQSLDEAISSGITTVVGGGTGPTDGSRATTCTPAPTQMKLMLQSTDDIPLNFGFTGKGSGSHPDELHEIIKAGAMGLKLHEDWGCTPAAIDNCLAVAEQHDIQVNIHTDTVNESGFVEHTIAAFNGRTIHTYHSEGAGGGHAPDIIKVCSMKNVLPSSTNTTRPLTSNTVDEHLDMLMVCHKLNREIPEDLAFASSRVREQTIAAEDILHDIGGISIISSDAQAVGRIGEVISCTWQTADKMKAERGPLQPDGSDNDNFRIKRYIAKYTINPAIVNGISQYVGSVEVGKLADLVIWKPSFFGAKPDIVIKGGSIAWADMGDPNGSIPTPEPVLMRPMYGTLGKAGSALSIAFVSKAALDLGVKVLYGLNKRVEAVSNVRKLTKLDLKLNNSLPEITVCPETFTVTVDGQALSSEAVTTLPLSQNYFIF
What is the function of this protein?
Urea hydrolase involved in recycling metabolically derived urea generated internally or externally (By similarity).  Is able to impair growth of the phytopathogenic fungus Penicillium herguei, and shows entomotoxic activity by inhibiting diuresis in Malpighian tubules isolated from Rhodnius prolixus (PubMed:21893219).
What are the official names of this protein?
Urease 2, Jaburetox, Jack bean urease II, Urea amidohydrolase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
Protein: SYGB_NITEU
Sequence: MMIENLLIELLTEELPPKSLDKLGNAFAAVIADSLKSQNLTTPDTILTAFASPRRLAVHLTAIPAQAPDQVVALKLMPITVGLDAQGQPTPALHKKLAALGMENVDASALKRVQESKAEMLFLEQNVTGILLAAGLQKAMEDAIRQLPVSKVMTYQLDDGWENVHFVRPVHGLIALHGQKIIPVSAFGLTAGNTTRGHRFEVKQTELIIDHADRYASLLETEGAVIPGFDRRRSWIREGLEAAASAVQLRCISDEVLLDEVTALVEYPNILMGAFPTDFLEVPQECLISTMKINQKYFPLLDTDGKLTNQFLIVANITPADPGQIISGNERVIRSRLADAKFFFDHDRKRTLASRLPDLDKVIYHHQLGSQGERTRYVQTLARIIGRLLGDDNLAGQADQAAMLAKADLLTDMVGEFPELQGIMGRYYARFEGMDETIAFAIEDHYKPRFAGDVLPRSMAGICVALADKLETLISLFSIGQLPTGDKDPYALRRHALGVIRILIEKNLPIGLDVLISRAADVLQDEMIGKQDSGPGHARPVTPQLVGQLQDFFYDRLAASLRDQGYTAQEVEAVLNLRPSLLCEIPRRLAAVRAFAALPEAASLAAANKRVGNILKKSECDATVAIDEACLQASAEITLYRALSEIESDARQAFQNGDYVTALQILAALKAPVDAFFDQVMVNDENEALRRNRLALLMALQATMNRVADISRLAA
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_HALWD
Sequence: MANGKYAARKLKQDRQQRRWSDSEYARRERGLGAKSDPLEGAPQGRGIVLEKVGIEAKQPNSAIRKCVRVQLIKNGKQVTAFCPGDGAISFIDEHDEVTIAGIGGAKGRAMGDLSGVNYKVEKVNGVSLIELVRGNAEKPVR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RLMN_PSYIN
Sequence: MNIKKVNLLDLNREGLRAFFVELGEKPFRAEQVMKWIYHYGCEDFDLMSNVNKKLRQKLKECAEIVAPEIKVEQRSNDGTIKWAMTVGDQEVETVYIPEKDRATLCISSQVGCVLACNFCSTAQQGFNRNLSVSEIIGQVWRAAKIVGVTGESGKRPITNVVMMGMGEPLLNLNNLIPAMELMLDDFGYALSKRRVTVSTSGVVPALDILGDRIDVSLAISLHAANDTLRSQMMPINDKYNIADFLAGVKRYIAKSKANRGKVYIEYLLLDHFNDSTDQAHELAILLKDTPCKINLIPFNPFPGNDYQKPSNSRVDRFNKVLMEYGYTVTVRKTRGDDIDAACGQLVGDVIDRTKRTMKKRLQGENIAISAG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DB114_HUMAN
Sequence: MRIFYYLHFLCYVTFILPATCTLVNADRCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKLYEEDDMF
What is the function of this protein?
Has a salt-sensitive antimicrobial activity against Gram-negative bacteria, including E. coli, Gram-positive, including S. aureus, and fungi, including C. albicans.  Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS.  Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.
What are the official names of this protein?
Beta-defensin 114, Beta-defensin 14, DEFB-14, Defensin, beta 114.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_MYCPN
Sequence: MAKLSKKMKIAVGLVDKTKLYPLQEAVDLVKKTSITKFNGSVDIAVSLNLDTTKAEQQLRGAIAFPHSVGKPIRILAITDDEKAALEAGADFVGGIDKINDIKNGWLDFDLIITSPKFMAALGKLGKLLGTKGLMPNPKTETVTDDVPAAVRAYKKGKKEYRADSFGNIHMSLGRVDSASNHLVENALALLDLIKSRKPATVKGIYIKNIALTTTMGPSLKVKLPD
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PP364_ARATH
Sequence: MLSPSLPRMNILGFTVNFLIRCKVLPRRSNTSSLSRNISVLASYDQEEVSPGRYSNEFSNRNLVHEILQLCARNGAVMEAKACHGKIIRIDLEGDVTLLNVLINAYSKCGFVELARQVFDGMLERSLVSWNTMIGLYTRNRMESEALDIFLEMRNEGFKFSEFTISSVLSACGVNCDALECKKLHCLSVKTCIDLNLYVGTALLDLYAKCGMIKDAVQVFESMQDKSSVTWSSMVAGYVQNKNYEEALLLYRRAQRMSLEQNQFTLSSVICACSNLAALIEGKQMHAVICKSGFGSNVFVASSAVDMYAKCGSLRESYIIFSEVQEKNLELWNTIISGFAKHARPKEVMILFEKMQQDGMHPNEVTFSSLLSVCGHTGLVEEGRRFFKLMRTTYGLSPNVVHYSCMVDILGRAGLLSEAYELIKSIPFDPTASIWGSLLASCRVYKNLELAEVAAEKLFELEPENAGNHVLLSNIYAANKQWEEIAKSRKLLRDCDVKKVRGKSWIDIKDKVHTFSVGESGHPRIREICSTLDNLVIKFRKFGYKPSVEHELHDVEIGKKEELLMQHSEKLALVFGLMCLPESSPVRIMKNLRICVDCHEFMKAASMATRRFIIVRDVNRFHHFSDGHCSCGDFW
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g04780, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UL96_HHV6Z
Sequence: MSLKDYLRQSISKDLEVRHRDSLKIRLGERHPLSVHQHMIAARQIIKSDNAEHQHVISSLSGFLDKQKSFLKVQQRALKQLEKLDVDEIIDTAAEVKAVSNNIKETLMASTELE
What are the official names of this protein?
Protein U68.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL96 family.
Protein: NANT_ECOSE
Sequence: MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLACGFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHGGKAPVRTMVDILYRGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPTGVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYDPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CX6A_CONIM
Sequence: MKTGMIICLLLIAFMDADGSPGDTLYSQKTADTDSGMKRFQKTFQKRRCVFCPKEPCCDGDQCMTAPGTGPFCG
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Im6.10, Conopeptide im029.
What are the subcellular locations of this protein?
Secreted.
Protein: VIS_VIBS1
Sequence: MNTRFLLLLCCLSFTTFSQPFDAIKQPNRSEEEVTQLAEDFKDWSKASNGWRYSFITANEKEAVEDFSISGYQTANDYLRATDTSTWGVAGADARQYIRTVKSALNKLPKYKGTAYRGTWVKLSLLNKLEEGDVLVEPAFTSTSTLPEVAKRFSVVHPNSPQRLKRVLFEVKINQGGHTIAGLSEYSKEAEVLFAPNAHFRITQIERTSNHTYIGVETVKASAVKNTQKYNLYSGEEVEASFWHSLVCT
What is the function of this protein?
A probable mono(ADP-ribosyl)transferase, it may ADP-ribosylate Arg in target protein(s).  Upon expression in yeast cells causes cell death.
What are the official names of this protein?
Putative NAD(+)--arginine ADP-ribosyltransferase Vis, Putative mono(ADP-ribosyl)transferase, mADPRT, mART, Toxin Vis.
What is the protein family that this protein belongs to?
Belongs to the Arg-specific ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Secreted.
Protein: IBPB_ECO5E
Sequence: MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAENMEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTU6B_DANRE
Sequence: MEEVETAEEQLAKQHRKEKKDLQAKIQSMKNAVPKNDKKRRKQLTEDIAKLEAELSQKHENELKLQNTSSVEEVSDALDSMSVANHEEQSDPSKQSRTSKAQKRRDKKAALEKEREMRIAEAEVENLSGSRHQEGLKLREKLVERHLQIKEISSDGHCMYRAVEHQLTERGLALGLKELRDQTAQYMRSHADDFMPFLTNPNTGDMYTAEEFEKYCSDVADTAAWGGQLELKALSQVLQLPIEVIQADSPCITIGEEYDKPKITLIYMRHAYGLGEHYNSVEPLKDLANEEEG
What is the function of this protein?
Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of different cellular processes.
What are the official names of this protein?
Deubiquitinase OTUD6B.
Protein: PBN1_YEAST
Sequence: MVTRHRVTVLYNAPEDIGNHMRQNDTHLTVRGGSGVVLQQRWLLERTGSLDKSFTRITWRPRADLARSLSVIENELSAGFSVYSNSSDVPERFITNPVYNSFHSEKFDIEQYLPPEVDLNLSWNPEDFTYDISVEPTQIQIVEYRLLKQGEEFTIARVKDEKLEVGVFFVDASDESDVDIGGIRCNWRMDDGKMERCQKTSLLYKQGHIAYNHSTTTTSLYLNEPIGLHPKIMIDLTDFEERPKCMYLMHLQLPLELFIDKFQSSPLLLFGEDDLELPEYSLRDKAWGSESIFELKAGTMNEVTLHTRYIEPSNNKGDKLEVSFDPEVILACDTGDNKVSRNPFYKKGLGYESLFTDDTTFRHLNSTTLLVPIPRPDTKDYSKIKNGTLLCLLISIIYIFSKVFGNNKKKRSVKRE
What is the function of this protein?
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum.  Aids the autocatalytic processing of PRB1.  Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.  Probably acts by stabilizing the mannosyltransferase GPI14.
What are the official names of this protein?
Protein PBN1, Protease B non-derepressible protein 1.
What is the protein family that this protein belongs to?
Belongs to the PIGX family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: RL36_CALS8
Sequence: MKVRPSVKPICEKCKVIRRKGKIRIICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: MNMG_ANAMF
Sequence: MFYIIWLVVVLSYEVVVVGGGHAGCEAAAAAARVGAKTLLITHKIGSIGEMSCNPAIGGVAKGVVVREVDALDGLMGQAIDKASIHSTILNQSKGPAVWGPRAQADRDAYRTAMQDIVLGYKNLEVLEASVIDFSTDNEAGSPCVASVTLSCGKVLHTRRLVLATGTFLGGMIHVGRDKGIPAGRMGDKPSTRLAKALCAHGFMLGRLKTGTPPRIDRSSIDWSATAEQKGDLVPTPFSFLSDAIVLPQVSCYITHTNTKTHEIVRNNLHLAASCASLVDVAAPRYCPSIEEKVRRFPEHKSHQVFLEPEGLDSNSVYPNGVSTSCPIDVQLEMLRSIRGLENVRMLRHGYTVEYNFVDPRELHHTLETKKIKGLYFAGQINGTTGYEEAAGQGIVAGANAALSLSQNHAPFVLKRSEAYIGVMIDDLVTLGTSEPYRLFTSRAEYRLRLRSDNADMRLTEMGYNAGLVSERRFGVLYNKKQEMDRLVEELHRTSITPHTLSKCGIFISQNGEKKTAFELLGHPSITMDILIQLWPSLNSFSRAALAAVGIEGKYAPYLQRQAADIQSFLEEENASIPADIRYSEVHGLSKEAQEKLQRAQPFSIGAARRIPGITPAAIANIIIHLRCRGRASHQNS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y741_STAAC
Sequence: MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD
What are the official names of this protein?
UPF0178 protein SACOL0741.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: AAT6_CAEEL
Sequence: MLNVFGVSASMPDDSRSQKMGLLGAISYIVGNIVGSGIFITPTSIIENVNSVGLSLAIWILAAFISMLGSFCYVELGTSIRLSGGDFAYLCFMKWYPVAFAFMCIGCTINYPATLAVQAQTFAEYVFRGAGVELDETSEFWAKKLLGFSLIILLMFMNFFSLKTFVQRFSILASLAKIAATLLIIITGFYYLIFKHWKQNLEEPFKGSNWNPGPFVNALFAGLFSYDGWDILNFGAEEIENPKRTMPLSIIIGMTCIGVIYVAVNVAYSIVLSPTEMIASNAVAIDFANKTLGAAAFVVPVMVAILLIGSLNSTMFSASRYLQAVSRQGHIPSAISGIAPNCDSPRVALLVHILIAIAVSFLGDPDKLINYVAFAQWSQRAFTMSALLYLRIRGRPRHPDRIQLPIIMPILFFLVCTSMVVISIIDDFKSSAVGLGILLGGLIIFIIFVWDRALPSSHTFRNATHVINEESTKFMQIIFNVVPERVGDEEMKNAIGGAESESEKVPAYKISPTGNGQFKCTRM
What is the function of this protein?
Amino acid transporter that mediates the uptake of the L-enantiomers of various amino acids, including L-glutamate (Probable).  May play a role in promoting fertility (PubMed:30560135).
What are the official names of this protein?
Amino acid transporter protein 6.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Co-localizes with nrfl-1 at the apical cell membrane of intestinal cells.
Protein: RL2_TRIV2
Sequence: MGTRSYRPYTPSTRQVTISDFAEITKTEPEKSLTVYKHRAKGRNNQGRITSRRRGGGHKRLYRIIDFKRDKRSIPATVIAIEYDPNRNARIALVSYEDGEKRYILHPNNLKVGTVIIAGPESPIEDGNALPLANIPLGTSVHNVELKAGKGGQIVRSAGATAQVVAKEGNYVTLKLPSGEVRLIRRECYATIGQVGNTDARNLSAGKAGRNRWKGRRPKVRGSVMNPVDHPHGGGEGRAPIGRSGPVTPWGKPTLGAKTRKPKKASSKLIIRRRRKSSKRGRGGRES
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SYCN_YERPS
Sequence: MSWIEPIISHFCQDLGVPTSSPLSPLIQLEMAQSGTLQLEQHGATLTLWLARSLAWHRCEDAMVKALTLTAAQKSGALPLRAGWLGESQLVLFVSLDERSLTLPLLHQAFEQLLRLQQEVLAP
What is the function of this protein?
Functions as a specific chaperone for YopN.  It could facilitate the secretion and the subsequent translocation of YopN (By similarity).
What are the official names of this protein?
Chaperone protein SycN.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein. Note=Not exported across the inner membrane.
Protein: CYSH_VIBPA
Sequence: MLDSVASKPELAELLTLTKTEQILRLAQINVELEPLSAQERVKWALENLDGEFAVSSSFGIQAAVMLHLVTQEKPDIPIILTDTGYLFAETYRFIDELTEKLNLNLKVYRAEQSAQWQEARYGKLWEQGVEGIEKYNKINKVEPMRRALKELNVGTWFSGLRREQSKSRAGLPILSIQNGVFKFLPVIDWTNKDVHYYLEQHGLTYHPLWEEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEDDGNEQDGSGI
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_SALTI
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: CODY_BACC3
Sequence: MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLFNITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAEEIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNDKFLHELAKLKTN
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR3_LUCCU
Sequence: SANTKNDFMRF
What are the official names of this protein?
FMRFamide-3, LucFMRFamide-3.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.