PharMolix/UniProtQA huggingface dataset:
Protein: MUTS2_CLONN
Sequence: MNEKSLRVLEFNKIKDELKKYTQTSAAKDLIERLHPYESAYEVREHLMETEEAFKISIKKGDAPFSGLYDIREAISKAQRRFTLFPSELLRVANLLRASRRFKGYVKSDDLSEKYEVLESITEGLVPLNGLEEEISKCIIGEEEISDRASTTLFNIRRSLKDKTSSIKARVNSLIRTYSSHLQENIYTVRGERYVLPVKVEHKGAVPGLVHDQSASGATLFIEPMSLVDLNNEIKELRLKEKAEIDRILAFLSGKVYENVDVIKVDADILWELDFIFAKAKYAQKLGAIMPIISEDGHFNIINAKHPLIDPKKVVENNIYLRDGITSVVITGPNTGGKTVTLKTVGLLHIMAMSGLMITASQGSTISFFKEVFADIGDEQSIEQSLSTFSSHMTNIVNIIDSADENSLVLFDELGAGTDPTEGAALAVSILENLRKRKTKVIATTHYSELKAYALKVDNVENASVEFDVETLRPTYRLLIGVPGKSNAFEISKRLGLPDYIIEDAREGISEETLKFEDLIQSLQHKNIKAQEHARKAESAKEEAVKLKEKYESKLDKFQDIREKAILNAQKEAKEIIKEAKEEADKILKDIRELERMGYSSDVRKLLEENRKKLKDKLEKTESKLNQPKEVGEAVTNVSEGDELYLPKFETKVMVLTNPDNKGDVQVQAGIMKIKVNIKDLRKTKETKIEKRQRKKKQMSLNLKSVATSVDLRGMDSEEATYTADKYLDDACMSGLSEVTIIHGKGTGVLRTAINDMLKRHPHVKSYRLGNYGEGGNGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: KCY_PECCP
Sequence: MTVMAPVVTVDGPSGAGKGTLCKALAEALQWNLLDSGAIYRVLALAALHHHVDISSEDALVPLASHLDVRFVAEGGQLKVILEGEDVSHEIRTEAVGNTASQAAAFPRVREALLRRQRAFREAPGLIADGRDMGTVVFPDAPVKIFLDASAEERAQRRMLQLQGKGFNVNFERLLSEIKERDERDRNRPVAPLVPAADALVLDSTEMTIDEVIARALAYAREILA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANGL4_PIG
Sequence: MRSAPTARAALVLCAATAGLLSAQGSPEPPEAPRFASWDEVNVLAHGLLQLGRGLREHVERTRGQLGALERRLSACGAACKDPEGSAVPPLTAGNLVPSQSDAAPETLHSLQTQLKAQNSKIQQLFQKVAQQQRHLEKQHLRIQNLQGQLDHLAPMHLGHGVAKAARRKRLPKMTQPAGPAHNISRLHRLPRDCQELFEEGERQSGLFQIQPQGSPPFLVNCKMTSDGGWTVIQRRQDGSVDFNQPWEAYKDGFGDPKGEFWLGLEKVHRIMGDRGSRLAVQLQDWEGNAESLQFPVHLGGEDTAYSLQLTAPVASKLGATIDTPSGLSLPFSTWDQDHDLRGDKNCAKILSGGWWFGTCSHSNLNGQYFHSIPRQREQRKKGIFWKTWRGRYYPLQATTMLIQPTVAEAAS
What is the function of this protein?
Mediates inactivation of the lipoprotein lipase LPL, and thereby plays an important role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism.  Has higher activity in LPL inactivation than the uncleaved protein.
What are the official names of this protein?
Angiopoietin-related protein 4, Angiopoietin-like protein 4.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Note=The unprocessed form interacts with the extracellular matrix. This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4.
Protein: ISPG_RENSM
Sequence: MTSVSLGMPAAPPPVLAPRRKTRQIKVGSVGVGSDSPISLQSMTTTPTTDINATLQQIAELTASGCDIVRVACPSADDAEALPIIAKKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGNIRKFDDQIKEIAQAAKDHGTSIRIGVNAGSLDPRLMEKYGKATPEALVESAVWEASLFEEHDFHDFKISVKHNDPVVMVRAYELLAERGAWPLHLGVTEAGPAFQGTIKSATAFGALLSKGIGDTIRVSLSAPPVEEIKVGNQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAEEVTAGLEGMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESQIVETLIEEAMRIAEEYEEMGGEDGQGGIKGSPVVSVS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: OR4F6_HUMAN
Sequence: MDEANHSVVSEFVFLGLSDSRKIQLLLFLFFSVFYVSSLMGNLLIVLTVTSDPRLQSPMYFLLANLSIINLVFCSSTAPKMIYDLFRKHKTISFGGCVVQIFFIHAVGGTEMVLLIAMAFDRYVAICKPLHYLTIMNPQRCILFLVISWIIGIIHSVIQLAFVVDLLFCGPNELDSFFCDLPRFIKLACIETYTLGFMVTANSGFISLASFLILIISYIFILVTVQKKSSGGIFKAFSMLSAHVIVVVLVFGPLIFFYIFPFPTSHLDKFLAIFDAVITPVLNPVIYTFRNKEMMVAMRRRCSQFVNYSKIF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4F6, Olfactory receptor 4F12, Olfactory receptor OR15-15.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPDF_RHOCB
Sequence: MTVAVIIVAAGRGTRAGEGLPKQWRDLAGRPVLAQTVAAFAGLGRILVVLHPDDMGLGMDLLGGSVVLVAGGSTRSESVKNALEALEGSDVTRVLIHDGARPLVPASVTAAVLAALETTPGAAPALAVTDALWRGEAGLVAGTQDREGLYRAQTPQGFRFPEILAAHRAHPGGAADDVEVARHAGLSVAIVPGHEDNLKITYAPDFARAEAILRERKGLTMDVRLGNGYDVHAFCEGDHVVLCGVKVPHVKALLGHSDADVGMHALTDAIYGALAEGDIGRHFPPSDPQWKGAASWIFLDHAAKLAKSRGFRIGNADVTLICERPKVGPHAVAMAAELARIMEIEPSRVSVKATTSERLGFTGREEGIASIATVTLIGA
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: NU4LM_PLABC
Sequence: MSLTYMNMFMAFTISLLGLLLYRSHMMSSLLCLEGMMLSLFVMMTMIILNTHLTLASMIPIILLVFAACEAALGLSLLVMVSTTYGMDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LPXC_HAEIE
Sequence: MIKQRTLKQSIKVTGVGLHSGEKVTLTLRPAMPNTGVVYYRTDLNPTVAFPADPNSVRDTMLCTALINEQGVRISTVEHLNAALAGLGIDNIIIEVDAPEIPIMDGSASPFIYLLLDAGIEEQNAAKKFIRIKEYVRVEDGDKWAEFKPYNGFRLDFTIDFDHPAIGKDVRNYEMNFSAQAFVHQISRARTFGFMKDIEYLQSQGLVLGGSLDNAIVLDDYRILNEDGLRFKDELVRHKMLDAIGDLYMAGYNIIGDFKAYKSGHGLNNKLLRAVLANQEAWEFVTFEDKEQVPQGYVAPAQVLI
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: PKHH2_MOUSE
Sequence: MEEPSEPEGLIDWKERCVALEAQLMKFRVQASKIRELLADKMQQLERQVIDAERQAEKAFQEVQVMEEKLKAANIQTSESETRLYKKCQDLESVMQEKDDIIQNLALRLEEQKQVRIQEAKIIEEKAAKIKEWVTVKLNELEVENQNLRFINQTQTEEIRAIQSKLQELQEKKISCVSSPKTSEGQRNLTFGCFLSRAKSPPCVVRCEEVSKMASNEPEITEGRCVEEMEIAEKPADNQVQENSRSQRKLHETSCSSEQNQKTRASFAMDGGTSQNSGVPVSDWSSDEDDGSKGRSKSRCTSTLSSHTSEEGGQCGRLGSEAYLTASDDSSSIFEEETFDGNRPEQKKLCSWQQKAPWKAQGNLAKGRSQSGVKEQDSSSDELNKKFHSQRLDYTSSSSEANTPSPILTPALTPRYPNSLPGKGGAPLVPPPFQPPPKLRVPNVFSISVALTKRHLSQPQLCSDRMFGTNRNAISMIRPLRPQETDLDVVDGDGAEAVNRMDTGCDDGLFSYDSQDPPPCADDQENSEAPKKAPCNKPPTPPLHRFPSWESRIYAVAKSGIRVSEAFNMEHANKNSADILSYSAASLYTSLIYKNMTTPVYTTLKGKATQISSSPFLDDSSGSDEEDSSRSSSRLSESDARSRSGPSSPRAMKRGVSDSSAASESDYAIPPDAYPIDAECSQPEQKLLKTCLASCDNGKNEPLEKSGYLLKMSVRVKTWKRRWFVLKGGELLYYKSPSDVIRKPQGHIELSASCSILRGDNKQTVQLATEKHTYYLTADSPNILEEWIKVLQSVLRVQAANPLCLQPEGKPAVKGLLTKVKHGYSKRVWCMLVGKVLYYFRNQEDKFPLGQLKLWEAKVEEVDRSCDSDEDYETRGCYLLSTHYTIIVHPKDQGPTYLLIGSKHEKEAWLYHLTVAAGSNNINVGSEFEQLVCKLLNIEGEPSSQIWRHPMLCHSKEGILSPLTTLPSEALQTEAIKLFKTCQLFINAAVDSPAIDYHISLAQSALQVCLTHPELQNEICCQLIKQTRRRQLQNQPGPLQGWQLLALCVGLFLPHHPFLWLLQLHLQRNADSRTEFGKYAIYCQRCVERTQQNGDREARPSRMEILSTLLRNPYHHSRPFSIPVHFMNGLYQVVGFDASTTVEEFLNTLNQDTGMRKPAQSGFALFTDDPSGRDLEHCLQGNIKICDIISKWEQASKEQQPGKCEGSRTVRLTYKNRLYFSVQARGETDREKTLLLYQTNDQIINGLFPLNKDLALEMAALLAQVDIGDFERPFSTPAGPVTNQCKANQTLKQVIERFYPKRYREGCSEEQLRQLYQRLSTKWMALRGHSAADCIRIYLTVARKWPFFGAKLFFAKPIAPSSLGNNCVWLAVHENGLSILEYTSMRLVTSYMYKGLMTFGGYQEDFMVVVSTQSKDRPTEKLLFAMAKHKILEITLLIASYINSFHQQKTTFHHLSAPALLSPRTQAPQARVMGSQPPLSNSRPTKGPTLL
What is the function of this protein?
In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane.  May be involved in stabilization of F-actin by attenuating its depolymerization.  Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia.
What are the official names of this protein?
Pleckstrin homology domain-containing family H member 2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Note=Localizes to the slit diaphragm and foot process of podocytes. Localization to peripheral regions of lamellipodia seems to be dependent on PI3K (By similarity).
Protein: DB125_MACFA
Sequence: MNLLILTFIICGLLTQVTKGSFEPQKCWKNNIGYCRRRCLDTERYILLCRNKLSCCISIIISYEYTRRPPFRVIHLEDITFDYSDMGSFTGSPVSKLSDLVTFDIRRETMTPKTNTPETTMPPSETTTSKTTMPSSKTTTSKTTMPPPSQMALTHN
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 125, Defensin, beta 125.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL17_CHLPD
Sequence: MRKVKPARKLGRTAAHRKATLSNLSTQLILHKRIETTEAKAKETRRVVEKIITKARKGTVHAQRIIFKDIRDKEAIKVLFEEIVAKIGTRNGGYTRVIKLAPRYGDAAKMAVIELVDYHEMPAEGQKPVKQDRSKRVKGSKKSEVAS
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: CYB_MYODO
Sequence: MTNIRKSHPLMKIINNSFIDLPTPSNISSWWNFGSLLGICLALQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWILRYLHANGASMFFICLYLHVGRGLYYGSYMYTETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFLLPFIIAAMVMVHLLFLHETGSNNPTGIPASADMIPFHPYYTIKDILGLLLMITALLTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILIIIPLLHTSKQRSMTFRPLSQCLFWLLTADLFTLTWIGGQPVEHPYVIIGQLASILYFSIIIILMPLISLMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DHAA_BRADU
Sequence: MSKPIEIEIRRAPVLGSSMAYRETGAQDAPVVLFLHGNPTSSHIWRNILPLVSPVAHCIAPDLIGFGQSGKPDIAYRFFDHVRYLDAFIEQRGVTSAYLVAQDWGTALAFHLAARRPDFVRGLAFMEFIRPMPTWQDFHHTEVAEEQDHAEAARAVFRKFRTPGEGEAMILEANAFVERVLPGGIVRKLGDEEMAPYRTPFPTPESRRPVLAFPRELPIAGEPADVYEALQSAHAALAASSYPKLLFTGEPGALVSPEFAERFAASLTRCALIRLGAGLHYLQEDHADAIGRSVAGWIAGIEAVRPQLAA
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
Protein: GCSPA_GEOUR
Sequence: MSYCPNTPEDIREMLAAIGVASVDALFAPIPAGLRARSFALPDGTSEQELLRQMKQLAGTDRPVTGFIGGGYYDHYIPAVVDHLSGRAEFYTAYTPYQPECSQGTLQALFEYQTAICRLTGMEVSNASLYDGGTALAEAAMMALRVTGRNRLVIDGSVNPFSREIVRTYLTNLGVEIVEIPARDGLADRPALTAALTDLTAAVILQNPNFFGSVEDLSDIALTAHANGALLIASVYPISLGLVKSPGAMGADIVVGDGQSLGNPLSFGGPSFGFIATTKKYIRNLPGRIIGETVDKSGRRGFVLTLQAREQHIKRHKATSNICSNQSLCALRGMIFLASVGKEGLVDLARLNRDKAEYAKGLLGSIKGVKLLNTAPTFNEFTIVLPKDAAEVAERLLGKGVAAGVPLGAYYHGMDNCLVVTVTEKRTRDEIDALAKELEGAL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: GATA_CORGB
Sequence: MTNKYLVEGSENELTTKTAAELAGLIHSREVTSREVTQAHLDRIAAVDGDIHAFLHVGQEEALNAADDVDKRLDAGEAPASALAGVPLALKDVFTTTDAPTTAASKMLEGYMSPYDATVTRKIREAGIPILGKTNMDEFAMGSSTENSAYGPTHNPWDLERTAGGSGGGSSAALAAGQAPLAIGTDTGGSIRQPAALTNTVGVKPTYGTVSRYGLIACASSLDQGGPTARTVLDTALLHEVIAGHDGFDATSVNRPVAPVVQAAREGANGDLKGMKVGVVKQFDRDGYQPGVLEAFHASVEQMRSQGAEIVEVDCPHFDDALGAYYLILPCEVSSNLARFDGMRYGLRAGDDGTRSADEVMAYTRAQGFGPEVKRRIILGTYALSVGYYDAYYLQAQRVRTLIAQDFAKAYEQVDILVSPTTPTTAFKLGEKVTDPLEMYNFDLCTLPLNLAGLAGMSLPSGLASDTGLPVGLQLMAPAFQDDRLYRVGAAFEAGRK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PTMA_PENSI
Sequence: MSRVIRSILIILGSVALYTKYYLSFQNGFIDLLSTMGSQGSLAGLQSGLRSHYTGLDPLDRFLKACNVFFWPIFHGTSPALSLYAIAFAGSMIPMWLILLMHTCVNSSIVEIVMINALAGLLVQGIGPGVIMCVLLAMRNTSMKEFAVTGIPAVSILGPNDLPLSLVVCYILPLALSSLPAPASISVPSKQLFIAIWQGWPLYIALAVGIAHSLRNHYRRNRPQQLFRHAYAFALACSIISHVGLLSISFLSVSPQSPFLSLHSADLHPRSLLIPRLPWQEVKITSLESGVLRFLHWDYSISSTGTLLWCYDVYWKDRMRGRGWIAFFSLSSRLATMSLAFGPCSVALALYWAALSNNLMKSENARKR
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of the indole diterpenes penitrems (PubMed:25831977).  The geranylgeranyl diphosphate (GGPP) synthase ptmG catalyzes the first step in penitrem biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:25831977).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase ptmC then forms 3-geranylgeranylindole (3-GGI) (PubMed:25831977).  Epoxidation by the FAD-dependent monooxygenase ptmM leads to a epoxidized-GGI that is substrate of the terpene cyclase ptmB for cyclization to yield paspaline (PubMed:25831977).  Paspaline is subsequently converted to 13-desoxypaxilline by the cytochrome P450 monooxygenase ptmP, the latter being then converted to paxilline by the cytochrome P450 monooxygenase ptmQ (PubMed:25831977).  Paxilline is converted to beta-paxitriol via C-10 ketoreduction by the short-chain dehydrogenase ptmH which can be monoprenylated at the C-20 by the indole diterpene prenyltransferase ptmD (PubMed:25831977).  A two-step elimination (acetylation and elimination) process performed by the O-acetyltransferase ptmV and ptmI leads to the production of the prenylated form of penijanthine (PubMed:25831977).  The FAD-linked oxidoreductase ptmO then converts the prenylated form of penijanthine into PC-M5 which is in turn transformed into PC-M4 by the aromatic dimethylallyltransferase ptmE (PubMed:25831977).  Five sequential oxidative transformations performed by the cytochrome P450 monooxygenases ptmK, ptmU, ptmL, ptmN and ptmJ yield the various penitrem compounds.  PtmK, ptmU and ptmM are involved in the formation of the key bicyclic ring of penitrem C via the formation of the intermediates secopenitrem D and penitrem D.  PtmL catalyzes the epoxidation of penitrem D and C to yield penitrem B and F, respectively.  PtmJ catalyzes the last benzylic hydroxylation to convert penitrem B to prenitrem E and penitrem F to penitrem A (PubMed:25831977).
What are the official names of this protein?
Terpene cyclase ptmA, Penitrem biosynthesis cluster 1 protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound ascI terpene cyclase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AB12B_HUMAN
Sequence: MDAQDCQAAASPEPPGPPARSCVAAWWDMVDRNLRYFPHSCSMLGRKIAALYDSFTSKSLKEHVFLPLIDMLIYFNFFKAPFLVDLKKPELKIPHTVNFYLRVEPGVMLGIWHTVPSCRGEDAKGKDCCWYEAALRDGNPIIVYLHGSAEHRAASHRLKLVKVLSDGGFHVLSVDYRGFGDSTGKPTEEGLTTDAICVYEWTKARSGITPVCLWGHSLGTGVATNAAKVLEEKGCPVDAIVLEAPFTNMWVASINYPLLKIYRNIPGFLRTLMDALRKDKIIFPNDENVKFLSSPLLILHGEDDRTVPLEYGKKLYEIARNAYRNKERVKMVIFPPGFQHNLLCKSPTLLITVRDFLSKQWS
What are the official names of this protein?
Protein ABHD12B, Abhydrolase domain-containing protein 12B, Alpha/beta hydrolase domain-containing protein 12B.
What is the protein family that this protein belongs to?
Belongs to the serine esterase family.
Protein: UVRA_ECO27
Sequence: MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLYARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKGEHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML
What is the function of this protein?
Plays a role in recovery after DNA ADP-ribosylation.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC1_OENBI
Sequence: MIDRYKHQQLRIGSVSPQQISTWANKILPNGEIVGEVTKPYTFHYKTNKPERDGLFCERIFGPIKSGICACGTYRVIGDKKEDPNFCEQCGVEFVDSRIRRYQMGYIKLACPATHVWYLKRLPSYIANLLDKPLKELEGLVYCDFSFARPVAKKPTFLRLRGLFEYEIQSWKYSIPLFFTTQGFDTFRNREISTGAGAIREQLAGLDLRVIIDYSLVEWKELGEERSTGNEWEDRKIGRRKQFLVRRVELAKHFIRTNIEPEWMVLCLLPVLPPELRPIIQMDGGKLMSSDINELYRRVIYRNNILADLLTTSRSTPGDLVMGQEKLVQEAVDTLLDNGIRSRPVRDGQNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPTLPLHRCGLPREIAIELFQTFLIRGLIRQHLASDIVGAKSQIREKEPIVWEILQQVMQGHPVLLNRAPTLHRLGIQAFQPILVEGRAICLHPLVCKGFNADFDGDQMAVHVPLSLEAQTEARLLMFSHMNLLSPAMGDPISVPTQDMLIGLYILTSGNPRGICTNRYNPWNRSNYQNERISDNNWKKKEPFFCNSYDAIGAYRQKRIHLDSPLWLRWRLDQRVIASREVPIEVQYESLGTYHEIYGHYIIVRSVKTEILWMYIRTTVGHISLFREMEEAIQGFCRARWYLS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NHAA_NOCFA
Sequence: MITRVRSELTRYLRTETVGGAILLVAAAIALLWVNSPWGDSYLRMTETVLAIEPLHLELTLADWTKDGLLAVFFFVAGLELKRELVVGELADPKRAALPIIAAVGGVVTPALIAAVIGHGAPGMDKGWAIPVATDIAFALGVLALTGSRIPATARVFLLSLAVVDDLLAIILIAVLFTVGVSLLWLLAAAACMAGWWLAQRRRLRTPLVYVPLALVTWYALHEAGVHPTLAGVALGLLTRVRPDPDEEWAPAARLEHLIQPVSAGICVPLFALFAAGVPLNATVFGELFTDRLALAVMLGLLLGKTIGIFGISWVAIRFGLATRPSGLGYRDMFALSVLGAIGFTVSLLVAELALPDGDTVELAKAAVLITSLAASLAGSALLLRRGRVHQARQDALELQPDEGDASDPSEGGSLR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RASEF_CAEBR
Sequence: MANPDVENLFSLCDSESKGFLTMEDLKKVCPQLDDNDLRFIFNELDRDGSGKIEKMEFLQGFQETVQHGESRGLNGMQRRASVAFDDGGPVFRRDELVFESESDSSSRPAIRVYDEEHYHSESDTNINIDFSVPCQEEVLVLYEQLQSSGVPALLRKFERVVGSFHKELSEKKHENERLQRIYASEREMYNRRMEEMESEVDQQLELIEMKARQEERERLTKEKEEMRERMSEEMSEMRTNIERLQRMEKVLERENERLNHQKDLSDKLKVVNEENNDLRQNLAENHLELAMIKSELAQVRADFDQKQDELSARRDQASHATEESESVRKQLQLLFDANRKLHETNESLRDALDSRASVLRQFNLRTPSPGLINSNRNSVENFQTSTNMFKSVPLHAISDEEPDPETSLILDDAHSLQGMDIAEGLVGLNDANGPAERTFRIVMCGDAAVGKSSFVMRVIRRQFTNQLPSTLGVDFHVKTVNVDGRNVALQLWDTAGQERFRSLCKSYFRRADGAILVYDVCAEHSFLRVRDWIETIKESTERSIPIILVGNKVDMRLQTPGAVAKTDGASMAAAMGVLFMETSALDGSNIDNAMLALTRELMAVEDVEIRSTGVVLNPAATKKGGCFSKCRGS
What is the function of this protein?
Binds GTP and GDP.  Plays a role in uterine seam cell development.
What are the official names of this protein?
Ras and EF-hand domain-containing protein homolog.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: DNLJ_LEIXX
Sequence: MAADARAEAQGLTTRILELRDAYYELDTVLVSDEEYDRMLRRLEELERLHPELQSQDSPTQTVGGRAQTTLFAPVEHAERMLSLDNVFSFEAFEAWAAKIERDAGRRVDYLCELKIDGLAINLRYENGVLVTAATRGDGVVGEDVTENIRHIPAITQRLSGAGPFPPVVEVRGEVFFPVAKFEELNANQQAAGERVFANARNAASGSLRQKAEGKNPAQRRLMRDRLGRLRMLVHGIGAWPNPPVATQSGVYELLRSWGLPTSAHGRVFGTVQEAADFIGRSAERRDTVEHEIDGVVIKVDELVLHDELGATSRAPRWAIAYKYPPEQVNTKLLDIVVSVGRTGRATPFAVMEKVKVAGSEVRQATLHNQDVVKAKGVLIGDTVVLRKAGDVIPEVLGPVVELRDGTEREFAMPTDCPECGTPLAPAKEGDIDLRCPNAEFCPAQVRGRVEHIGSRGGLDIEALGEVAAAALTQPRFPERAPLPTEAGLFGLRLEDLFPIEVVVRDSETGLPKLTETGVEKVDAPFRRRRQKKDGAFDPEAEAFDGDEIAVPSKSAIELLANLRAARTKPLWRILVSLNIRHVGPVAARALADHFGSLDAIRAASRDELAAVDGVGGIVADAVLSWFEIGWHCEIVENWARDGVQFAIPGHPGPGRADTGGGVLSGLTVVATGSLEGYTREAAQEAIVAAGGKAASSVSKKTDFVAAGPGAGSKLAKAEELGVRVLDAAQFTILVEQGPGALPEVAE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: AROE_ALKMQ
Sequence: MEFKISGYTRLVGLLGYPVRHSLSPLMHNMAFQHLGLDYVYLVFEVKEDNLKEAVDAMKTLDVAGFNVTMPNKQKIIPLLDEISEEARLIGSVNTVVNKNGHLKGYNTDGKGYVMGLADEGISPEGKTIVIAGAGGASKSVAIQLALEGAKEITILNRTVEAAEEICNIINKNIPTCKTSATGYEDNELKQQLKEADLFINCTNLGMGSHEEKSIISSTDILHPDLIVSDVVYAPPKTKLLHMAEEVGCKTINGLGMIIGQGALAFKLWTGEDMPIEYIKRIILSK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.