PharMolix/UniProtQA huggingface dataset:
Protein: SYM_SALAI
Sequence: MSHVLAAVAWPYANGPRHIGHVSGFGVPSDVFARYMRMTGHDVLMVSGTDEHGTPIQVQADAEGVTPRELADRYNRVIVADLHGLGLSYDLFTRTTTRNHYAVVQELFEGMYRNGYIVPKTTMGAISPSTGRTLPDRYIEGTCPICGYESARGDQCDSCGNQLDPIDLRNPKSKINGETPEFIETEHFFLDLPALAGVLRQWLDTREGWRPNVLRFSKNLLDDLQPRAITRDLEWGVPIPLEGWRDRGDKRIYVWFDAVIGYLSASIEWARRSGDPEAWRRWWSADGQGKDAPGYYFMGKDNIVFHSVIWPALLAGYSGEGSRDGQPGELGRMNLPTEVVSSEFLTMEGRKFSSSRRVVIYVRDFLERYDADALRYFIAVAGPESNDTDFTWAEFLRRNNDELVAGWGNLVNRSISMAAKNFGAIPPVDPAGLTEADEALLAVARAGFGAVGELIGRHRQKQAIGEAMKVVAEANRYLSEQAPWKLKSEADRPRMGTILHVALQVVSDANTLLTPFLPHSAQKIHELLGGTGVHAPMPVVEEVEDLDGGPAYPVLTGDYSVGARWESVPLEVGRPLDPPKPVFRKLDPSIVDEELARLAG
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIB_HAEIE
Sequence: MLKSNLKIDNRFSVMGVVSQLPKRLKSPSGIEHCKFLLEHRSDQIESGFTRQAWLKMPVQISGNQLIEKTQSITVGSKILVVGFITSHKTQSGLCQLVLHAEQIEFID
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: MOFA1_HUMAN
Sequence: MRPLDIVELAEPEEVEVLEPEEDFEQFLLPVINEMREDIASLTREHGRAYLRNRSKLWEMDNMLIQIKTQVEASEESALNHLQNPGDAAEGRAAKRCEKAEEKAKEIAKMAEMLVELVRRIEKSESS
What are the official names of this protein?
MORF4 family-associated protein 1, Protein PGR1, Protein associated with MRG of 14 kDa.
What is the protein family that this protein belongs to?
Belongs to the MORF4 family-associated protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Colocalizes with MORF4L1 to cell nuclei.
Protein: E2F6_HUMAN
Sequence: MSQQRPARKLPSLLLDPTEETVRRRCRDPINVEGLLPSKIRINLEDNVQYVSMRKALKVKRPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKKSKNHIRWIGSDLSNFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENERLAYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLCEVEQGQTSNKRSEGVGTSSSESTHPEGPEEEENPQQSEELLEVSN
What is the function of this protein?
Inhibitor of E2F-dependent transcription (PubMed:9689056, PubMed:9704927, PubMed:9501179).  Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' (PubMed:9501179).  Has a preference for the 5'-TTTCCCGC-3' E2F recognition site (PubMed:9501179).  E2F6 lacks the transcriptional activation and pocket protein binding domains (PubMed:9704927, PubMed:9501179).  Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression (PubMed:9689056, PubMed:9501179).  Represses expression of some meiosis-specific genes, including SLC25A31/ANT4 (By similarity).  May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity.  Overexpression delays the exit of cells from the S-phase (PubMed:9501179).
What are the official names of this protein?
Transcription factor E2F6, E2F-6.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCH1_SYNE7
Sequence: MTSPSLNGSNSLVDAIRPETEAVSQAEMEAAVRTLLLGVGEDPEREGLLKTPKRVAEAYRFLTSGYSQSLDDLVNGAIFDEGHNEMVLVRDITAFSLCEHHMLPFMGKVHVAYIPNQKVVGLSKLARIVEMYSRRLQVQERLTRQIAESVQEILDPQGVAVVMEATHMCMVMRGVQKPGSWTVTSAMVGVFQEDQRTREEFLSLIRHQPAAFA
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: DPOD_SCHPO
Sequence: MTDRSSNEGVVLNKENYPFPRRNGSIHGEITDVKRRRLSERNGYGDKKGSSSKEKTSSFEDELAEYASQLDQDEIKSSKDQQWQRPALPAINPEKDDIYFQQIDSEEFTEGSVPSIRLFGVTDNGNSILVHVVGFLPYFYVKAPVGFRPEMLERFTQDLDATCNGGVIDHCIIEMKENLYGFQGNEKSPFIKIFTTNPRILSRARNVFERGEFNFEELFPVGVGVTTFESNTQYLLRFMIDCDVVGMNWIHLPASKYQFRYQNRVSNCQIEAWINYKDLISLPAEGQWSKMAPLRIMSFDIECAGRKGVFPDPSIDPVIQIASIVTQYGDSTPFVRNVFCVDTCSQIVGTQVYEFQNQAEMLSSWSKFVRDVDPDVLIGYNICNFDIPYLLDRAKSLRIHNFPLLGRIHNFFSVAKETTFSSKAYGTRESKTTSIPGRLQLDMLQVMQRDFKLRSYSLNAVCSQFLGEQKEDVHYSIITDLQNGTADSRRRLAIYCLKDAYLPQRLMDKLMCFVNYTEMARVTGVPFNFLLARGQQIKVISQLFRKALQHDLVVPNIRVNGTDEQYEGATVIEPIKGYYDTPIATLDFSSLYPSIMQAHNLCYTTLLDSNTAELLKLKQDVDYSVTPNGDYFVKPHVRKGLLPIILADLLNARKKAKADLKKETDPFKKAVLDGRQLALKVSANSVYGFTGATNGRLPCLAISSSVTSYGRQMIEKTKDVVEKRYRIENGYSHDAVVIYGDTDSVMVKFGVKTLPEAMKLGEEAANYVSDQFPNPIKLEFEKVYFPYLLISKKRYAGLFWTRTDTYDKMDSKGIETVRRDNCPLVSYVIDTALRKMLIDQDVEGAQLFTKKVISDLLQNKIDMSQLVITKALSKTDYAAKMAHVELAERMRKRDAGSAPAIGDRVAYVIIKGAQGDQFYMRSEDPIYVLENNIPIDAKYYLENQLSKPLLRIFEPILGEKASSLLHGDHTRTISMAAPSVGGIMKFAVKVETCLGCKAPIKKGKTALCENCLNRSAELYQRQVAQVNDLEVRFARLWTQCQRCQGSMHQDVICTSRDCPIFYMRIAEHKKLQQSVDLLKRFDEMSW
What is the function of this protein?
Catalytic component of DNA polymerase delta (DNA polymerase III) which participates in chromosomal DNA replication (PubMed:31488849).  Required during synthesis of the lagging DNA strands at the replication fork, binds at/or near replication origins and moves along DNA with the replication fork (PubMed:31488849).  Participates in leading strand synthesis during replication initiation and termination (PubMed:31488849).  Has 3'-5' proofreading exonuclease activity that corrects errors arising during DNA replication (By similarity).
What are the official names of this protein?
DNA polymerase delta catalytic subunit, 3'-5' exodeoxyribonuclease, DNA polymerase III.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADT2_MOUSE
Sequence: MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIFISWMIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGSKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (PubMed:31341297).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).  In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (PubMed:31489369, PubMed:31341297).  Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis (PubMed:31341297).  Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A5/ANT2 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity) (PubMed:31341297).  Proton transporter activity requires free fatty acids as cofactor, but does not transport it (PubMed:31341297).  Probably mediates mitochondrial uncoupling in tissues that do not express UCP1 (PubMed:31341297).  Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1. 5 kDa, and which contributes to cell death (PubMed:31489369).  It is however unclear if SLC25A5/ANT2 constitutes a pore-forming component of mPTP or regulates it (PubMed:31489369).  Acts as a regulator of mitophagy independently of ADP:ATP antiporter activity: promotes mitophagy via interaction with TIMM44, leading to inhibit the presequence translocase TIMM23, thereby promoting stabilization of PINK1 (PubMed:31618756).  As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (By similarity).
What are the official names of this protein?
ADP/ATP translocase 2, ADP,ATP carrier protein 2, Adenine nucleotide translocator 2, ANT 2, Solute carrier family 25 member 5.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=May localize to non-mitochondrial membranes.
Protein: CTXI4_MESEU
Sequence: MCMPCFTTDHNMAKKCRDCCGGNGKCFGPQCLCNR
What is the function of this protein?
Toxin with unknown function in healthy organisms.  On glioma cells, interacts with chloride channels (probably ClC-3/CLCN3) and MMP2 at the surface of glioma cells.  This complex is then internalized via caveolae, thus inhibiting the chloride channels necessary for cell shrinkage and tumor propagation (By similarity).
What are the official names of this protein?
Insectotoxin-I4, BeI4.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Chloride channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: FA50B_MOUSE
Sequence: MAQYKGTMREAGRAMHLIKKREKQKEQMEVLKQRIAEETIMKSKVDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALLREREMQLAKREQLEQRRIQLEMLREKERRRERKRKISNLSFTLDEEEGDQEDSRQAESAEAHSAGAKKNLGKNPDVDTSFLPDREREEEENRLREELRQEWEAKREKVKGEEVEITFSYWDGSGHRRTVRMSKGSTVQQFLKRALQGLRRDFRELRAAGVEQLMYVKEDLILPHYHTFYDFIVAKARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDRYTIR
What are the official names of this protein?
Protein FAM50B, Protein XAP-5-like.
What is the protein family that this protein belongs to?
Belongs to the FAM50 family.
Protein: NDHH_FESAR
Sequence: MSLPLTRKDLMIVNMGPQHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNAPEFLENIQIPQRASYIRVIMLELSRIASHLLWLGPFMADLGAQTPFFYIFRERELIYDLFEAATGMRMMHNYFRIGGVAADLPYGWIDKCLDFCDYFLRGISEYQQLIKQNPIFLERVEGVGFISGEEAVNWGLSGPMLRASGIQWDLRKVDLYESYNQFDWKVQWQKEGDSLARYLVRISEMRESIKIIQQAIEKIPGGPYENLEVRRFKKAKNSEWNDFEYKFLGKKPSPNFELSKQELYVRVEAPKGELGIYLVGDDSLFPWRWKIRPPGFINLQILPQLVKKMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: Y1496_HAEIN
Sequence: MMNLILAFSGVIALYGGYLYLRLRQSQKQAATLQKEKEQLQTQKTVAETKVKNYQVKQKNEENLISRSRTSLLERMHNDGDLRD
What are the official names of this protein?
Uncharacterized protein HI_1496.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MNME_SYNS9
Sequence: MPPLDTIAAVATAVAPGQGGIAVIRLSGPVAEQVAQAVVQCPGHQEWGSHRILYGHVMAVDGQRRLDEVLLLLMRAPRSFTGEDVVEIHCHGGVMAVQQVLERVLEHPGVRRALPGEFSQRAVLNGRLDLTQAEAVSELVSARSRRAADLAMAGLDGGIQARITVLRERLLDQLTELEARVDFEDDLPPLDGTALLNELQAVRVELLALVADGERGDALRHGLRVALVGRPNVGKSSLLNRLSRRERAIVTELPGTTRDLLESEIVLDGVPITLMDTAGIRATNDAVEQLGIARSEEALISADVVVLIVDGHAGWTETDAQLLARIPNDVPRVVVANKSDLDGPPLPGLVDVQFSALNGAGEDAFVQVLLERCGAGDAAGIVLSLNTRQRDLASVAAAALERSHEVAQQQLPWDFWTIDLREAIRGLGEITGEELTEAVLERVFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIRUD_POEVI
Sequence: VVYTDCTESGQNLCLCEGSNVCGQGNKCILGSDGEKNQCVTGEGTPGPQSHNDGDFEEPEEYL
What is the function of this protein?
Hirudin is a potent thrombin-specific protease inhibitor.  It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.
What are the official names of this protein?
Hirudin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I14 (hirudin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CATA_PONAB
Sequence: MADSRDPASDQMKHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPLLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATEKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALEHSTQCSGEVQRFNTASDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSRIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
What is the function of this protein?
Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.  Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MTNW_BACSU
Sequence: MSELLATYLLTEPGADTEKKAEQIATGLTVGSWTDLPLVKQEQMQKHKGRVIKVEEREGTAASEKQAVITIAYPEINFSQDIPALLTTVFGKLSLDGKIKLIDLHFSEAFKRALPGPKFGVYGIRKLLGEFERPLLMSIFKGVIGRDLSDIKEQLRQQALGGVDLIKDDEIFFETGLAPFETRIAEGKQILKETYEQTGHKTLYAVNLTGRTADLKDKARRAAELGADALLFNVFAYGLDVMQGLAEDPEIPVPIMAHPAVSGAFTSSPFYGFSHALLLGKLNRYCGADFSLFPSPYGSVALPRADALAIHEECVREDAFNQTFAVPSAGIHPGMVPLLMRDFGIDHIINAGGGVHGHPNGAQGGGRAFRAIIDAVLEAQPIDEKAEQCKDLKLALDKWGKAEAV
What is the function of this protein?
Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
What are the official names of this protein?
2,3-diketo-5-methylthiopentyl-1-phosphate enolase, DK-MTP-1-P enolase, RuBisCO-like protein, RLP.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type IV subfamily.
Protein: ATPD_ACIET
Sequence: MAELATIARPYAEALYKACTDQAGVDLNGATAWVDELAAIAANPQLRQLADNPKVTGEQVFDVIVGVARSALPDLAKNFLRTVIDNGRVQALPEIAAQFRTLVNRSHGTSDAVVYSAFPLDAGALTDVGATLEKRFGRKLNLSVQLDETLIGGVRVVVGDEVLDTSVKARLEQMKAALTA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MRAZ_MYCGA
Sequence: MFIGNYQHNIDPKGRLSIPSKLRSLIQDSVVLSRGLDGCLELRTNQEFENYANKFLSQSNNKQQNRNYKRLLFANSLTVEIDSANRILIPANFKKMANLSKEVVIIGMGDHIELWDINAYEQFNEANFDKFNELAESMDDDH
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MURC_STRSY
Sequence: MTKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGIQILPFDEKNITADVELIAGNAFRPDNNVEIAYADAQGYTYKRYHEFLGEFMKGFTSLGVAGAHGKTSTTGLLAHVMRNITDTSFLIGDGTGRGSANAQYFVFESDEYERHFAPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQVKNALFVFGEDEQLRRITANAPIYYYGLEDNNDFVAYDLKPSTSGSQFKVRHGEEELGEFQIPTFGKHNVMNATAVIANLYIAGFDLQLVAEHLKTFGGVKRRFTEKIVNDTVIIDDFAHHPTEIIATIDAARQKYPSKELVAIFQPHTFTRTIALLDEFADALNGADAVYLAQIYGSARETDNGQVKVEDLAAKINKKGGLVTVENTSPLLDHDNAVYVFMGAGDIQSYEYSFERLLSNLTNNVQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODO1_BRUA4
Sequence: MARQEQANDVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGASWTRKNWPIAANGELISALDGNWAEVEKHVTDKLKGKAAKGEAKGATGAALTSEEITQAARDSVRAIMMIRAYRMRGHLHANLDPLGLSEKPNDYNELEPENYGFTPADYNRKIFIDNVLGLEYATVPEMLDILKRTYCGTIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKLIEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGAMGVKEIIFGMAHRGRLNVLSQVMGKPHRAIFHEFKGGSYAPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLEIVNPVVMGKARAKQDLLAGRTRDDMVPLATRAKVLPLLLHGDAAFAGQGVVAECLGLSGLKGHRVAGTLHFIINNQIGFTTNPAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAKVATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYSDKLIAEGLIKQEEIDQMKAQWRENLETEFDAGQSYKPNKADWLDGAWAGLRTADNADEQRRGKTAVPMKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGEGIDWATAESLAFGSLVAEGSPIRLSGQDVERGTFSQRHTVLYDQETQNRYIPLNNIQKGQAIYEAINSMLSEEAVLGYEYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGYEGQGPEHSSARLERWLQMCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRAVSTLNELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGIDDVYLLRVEQLYPFPAKALINELSRFRHAEMVWCQEEPKNMGAWSFIDPYLEWVLAHIDAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDALGN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: RL17_AGRVS
Sequence: MRHQKAGRKLNRTASHRKAMFANMAASLITHEQIVTTLPKAKEIRPIVERLVTLGKRGDLHARRQAISQIRDQDAVRKLFDAIATRYASRNGGYLRIMKAGFRQGDNAPLAVIEFVERDVDAKGAADKARVAAEAETAEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GATC_CAMJ8
Sequence: MQIDEKLLSKLEKLSALQITKNRNETIVQLSEIVNFVEKLNELDLDSQEITVSTIKGGAPLRIDEIRNSNVIDEVLDCAPKKQEHFFVVPKIIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: UREG_PROMT
Sequence: MESKLRVGIAGPVGSGKTAIIQRLCENLKDRLEIAVVTNDIYTQEDAKFLTNSKALAPERIKGVETGGCPHTAIREDCSINRIAVEELEHKFTTLDLVFVESGGDNLAASFSPELVDVCIYIIDVAAGDKIPRKGGPGITRSDLLVINKIDLAEMVGASLKIMERDTLLMRKNLPWCFTNTKTGEGIKIIEGFLCNQIPSVHKMV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_HAEIG
Sequence: MPVIKVRENESFDVALRRFKRSCEKAGILAEVRAREFYEKPTTIRKRENATLAKRHAKRNARENARNTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RL21_STAAM
Sequence: MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SMC3_PONAB
Sequence: MYIKQVIIQGFRSYRDQTIVDPFSSKHNVIVGRNGSGKSNFFYAIQFVLSDEFSHLRPEQRLALLHEGTGPRVISAFVEIIFDNSDNRLPIDKEEVSLRRVIGAKKDQYFLDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATAPDSQRLKLLREVAGTRVYDERKEESISLMKETEGKREKINELLKYIEERLHTLEEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDELQSERNYLWREENAEQQALAAKREDLEKKQQLLRAATGKAILNGIDSINKVLDHFRRKGINQHVQNGYHGIVMNNFECEPAFYTCVEVTAGNRLFYHIVDSDEVSTKILMEFNKMNLPGEVTFLPLNKLDVRDTAYPETNDAIPMISKLRYNPRFDKAFKHVFGKTLICRSMEVSTQLARAFTMDCITLEGDQVSHRGALTGGYYDTRKSRLELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDALNDEIRQLQQENRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQELNELRETEGGTVLTATTSELEAINKRVKDTMARSEDLDNSIDKTEAGIKELQKSMERWKNMEKEHMDAINHDTKELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQTLSLKQLFRKLEQCNTELKKYSHVNKKALDQFVNFSEQKEKLIKRQEELDRGYKSIMELMNVLELRKYEAIQLTFKQVSKNFSEVFQKLVPGGKATLVMKKGDVEGSQSQDEGEGSGESERGSGSQSSVPSVDQFTGVGIRVSFTGKQGEMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALDAQHRKAVSDMIMELAVHAQFITTTFRPELLESADKFYGVKFRNKVSHIDVITAEMAKDFVEDDTTHG
What is the function of this protein?
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle.  The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped.  At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.  Cohesion is coupled to DNA replication and is involved in DNA repair.  The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement (By similarity).
What are the official names of this protein?
Structural maintenance of chromosomes protein 3, SMC protein 3, SMC-3, Chondroitin sulfate proteoglycan 6.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation (By similarity). The phosphorylated form at Ser-1083 is preferentially associated with unsynapsed chromosomal regions (By similarity).