PharMolix/UniProtQA huggingface dataset:
Protein: UXUA_YERPS
Sequence: MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWSVVESVPIHEDIKTHSGNYQQYIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELPDGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEAYFNAMTEADIAKLTGNIIAGLPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRPILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLRSTCREGNPKTFHEGGHLQGDVDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDLHKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPDLKQ
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: LPXH_CHRSD
Sequence: MTTLLISDLHLHTGQPDITRGFLDYLERDARHADTLYLLGDIFEAWIGDDYLGDLERQVIEALRRLSDAGTQLYFMHGNRDFLVGEDFAAAAGATLLDDPCLATLGRQTVLLMHGDSLCTGDEEYMKFRAMARDPEWQAQILALPIEQRLELAKSLRMQSSDANTQKADAIMDVTPAEVEAIMREHGVSTLIHGHTHRPAVHEFTLDGQPAQRIVLGDWRPGRGWEVRVEDDAPPRLREFAFQARA
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IF4EA_SOLTU
Sequence: MAAAEMERTTSFDAAEKLKAADAGGGEVDDELEEGEIVEESNDTASYLGKEITVKHPLEHSWTFWFDSPIAKSRQTAWGSSLRNVYTFSTVEDFWGAYNNIHHPSKLVMGADFHCFKHKIEPKWEDPVCANGGTWKMSFLKGKSDTSWLYTLLAMIGHQFDHGDEICGAVVSVRSKGEKIALWTKNAANETAQVSIGKQWKQFLDHSDSVGFIFHDDAKRLDRSAKNRYTV
What is the function of this protein?
(Microbial infection) Susceptibility host factor required for viral infection (e. g.  Potato virus Y (PVY)) by recruiting viral RNAs to the host ribosomal complex via an interaction with viral genome-linked protein (VPg).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E allele A, eIF4E-A, eIF-4F 25 kDa subunit, eIF-4F p26 subunit, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RIPR1_HUMAN
Sequence: MMSLSVRPQRRLLSARVNRSQSFAGVLGSHERGPSLSFRSFPVFSPPGPPRKPPALSRVSRMFSVAHPAAKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYTTGSPGSREARDSLAEATRGHREYTESMCLLESELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIEGSGKQVWDSEETIFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASSVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSPAPRPLVQQPEPLPIQVAFRRPETPSSGPLDEEGAVAPVLANGHAPYSRTLSHISEASVDAALAEASVEAVGPESLAWGPSPPTHPAPTHGEHPSPVPPALDPGHSATSSTLGTTGSVPTSTDPAPSAHLDSVHKSTDSGPSELPGPTHTTTGSTYSAITTTHSAPSPLTHTTTGSTHKPIISTLTTTGPTLNIIGPVQTTTSPTHTMPSPTHTTASPTHTSTSPTHTPTSPTHKTSMSPPTTTSPTPSGMGLVQTATSPTHPTTSPTHPTTSPILINVSPSTSLELATLSSPSKHSDPTLPGTDSLPCSPPVSNSYTQADPMAPRTPHPSPAHSSRKPLTSPAPDPSESTVQSLSPTPSPPTPAPQHSDLCLAMAVQTPVPTAAGGSGDRSLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDEDNDVPGDRPPSSPEAGAEDSIDSPSARPLSTGCPALDAALVRHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEAVCEFSRRWEIPASSAQEVVQFSASRPGFLTFWDQCTERLSCFLCPVERVLLTFCNQYGARLSLRQPGLAEAVCVKFLEDALGQKLPRRPQPGPGEQLTVFQFWSFVETLDSPTMEAYVTETAEEVLLVRNLNSDDQAVVLKALRLAPEGRLRRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPTFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPRIFGPGSMASTAF
What is the function of this protein?
Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006).  Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006).  Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006).
What are the official names of this protein?
Rho family-interacting cell polarization regulator 1.
What is the protein family that this protein belongs to?
Belongs to the RIPOR family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Note=Localizes to the podocyte major processes and cell body (By similarity). Colocalized with STK26 in the Golgi of serum-starved cells and relocated to cytoplasmic punctae, probably vesicular compartments, along with STK26 upon serum stimulation in a Rho- and PDCD10-dependent manner (PubMed:27807006).
Protein: MNMA_BLOPB
Sequence: MSFNHIKKVIVGMSGGVDSSVSAWLLQQQGYKVEGLFMKNWEDDDSTEQCASASDLSDTHSVCDNLGIYLHTINFSKEYWENVFQVFLQEYSVGRTPNPDILCNKEIKFKYFLEFALQDLDADLIATGHYVRRVDMNKKTYLIRGVDRNKDQSYFLYTLSYKQLKQCLFPVGTLNKFQVRNIAKKLNLITANKKDSTGICFIGKRKFKDFISKYIPIRPGVIIDINGNTIGAHQGVSFYTLGQRKGLKIGGVKQGNGQPWYVIDKDTSNNTLIAAQGRNHPRLMSIAFITEQTQWVKRDALTSPLHCTVKTRYRHPDIQCQIYPLLNNNLKVILKIPVLAITPGQSAVFYLKERCLGGGIITKIYHC
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCL15_ARATH
Sequence: MKIPASSPQDTTNNNNNTNSTDSNHLSMDEHVMRSMDWDSIMKELELDDDSAPNSLKTGFTTTTTDSTILPLYAVDSNLPGFPDQIQPSDFESSSDVYPGQNQTTGYGFNSLDSVDNGGFDFIEDLIRVVDCVESDELQLAQVVLSRLNQRLRSPAGRPLQRAAFYFKEALGSFLTGSNRNPIRLSSWSEIVQRIRAIKEYSGISPIPLFSHFTANQAILDSLSSQSSSPFVHVVDFEIGFGGQYASLMREITEKSVSGGFLRVTAVVAEECAVETRLVKENLTQFAAEMKIRFQIEFVLMKTFEMLSFKAIRFVEGERTVVLISPAIFRRLSGITDFVNNLRRVSPKVVVFVDSEGWTEIAGSGSFRREFVSALEFYTMVLESLDAAAPPGDLVKKIVEAFVLRPKISAAVETAADRRHTGEMTWREAFCAAGMRPIQLSQFADFQAECLLEKAQVRGFHVAKRQGELVLCWHGRALVATSAWRF
What is the function of this protein?
Probable transcription factor involved in plant development.
What are the official names of this protein?
Scarecrow-like protein 15, AtSCL15, GRAS family protein 25, AtGRAS-25.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECA_VIBC1
Sequence: MITKLLTKVIGSRNDRTLRRLRKIVKEINNYEPTFEALSDEELKAKTVEFRERLEQGETLDKLLPEAFATVREASKRVYGMRHFDVQLIGGMVLNGGQIAEMRTGEGKTLTATLPAYLNALPGKGVHVVTVNDYLATRDAETNRPLFEFLGMTVGVNVPNMPPQAKKEAYQADILYGTNNEFGFDYLRDNMAFRNEDRVQRERFFAVVDEVDSILIDEARTPLIISGPAEDSSDLYTRINLLIPQLQKQDKEDSEEYRGDGHYTVDEKSKQVHLTETGQEFVEELMVKNGLMEEGDTLYSPTNISLLHHVNAALRAHVLFERNVDYIVNEDGEVVIVDEHTGRTMPGRRWSEGLHQAVEAKEGVKIQNENQTLASITFQNYFRLYEKLSGMTGTADTEAFEFQSIYGLETVVIPTNKPMIRNDMPDVVYRTEAEKFAAIIEDIKERVEKGQPSLVGTVSIEKSELLSNALKKAKIKHNVLNAKFHEREAEIVAEAGTPGAVTIATNMAGRGTDIVLGGSWQAKVEALQDPTKEQIDAIKAEWKQVHDQVLESGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDSLLRIFTSDRMASLIQSGMEEGEAIESKMLSRSIEKAQRKVEGRNFDIRKQLLEYDDVANDQRKVVYELRDELMSVDDISDMIEQNREDVITAIIDEYIPPQSLEDMWDVEGLQERLKADFDLDAPIKQWLEEDDKLYEEALREKITNLAVEVYKAKEEVVGAQVLRNFEKSVMLQTLDTLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFEGLLEALKTDVITVLSRVRVQQQEEVERMEEQRRAQAEEAARRAQAQHAAAQNPLSEGEESEEGAHQPMVREERKVGRNEPCPCGSGKKYKQCHGKID
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: GLPE_ECO5E
Sequence: MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAVQAFHLTNDTLGAFMRNNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPAEVAYGA
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_THESQ
Sequence: MEKMTIRDVDLKGKRVIMRVDFNVPVKDGVVQDDTRIRAALPTIKYALEQGAKVIFLSHLGRPKGEPSPEFSLAPVAKRLSELLGKEVKFVPAVVGDEVKKAVEELKEGEVLLLENTRFHPGETKNDPELAKFWASLADIHVNDAFGTAHRAHASNVGIAQFIPSVAGFLMEKEIKFLSKVTYNPEKPYVVVLGGAKVSDKIGVITNLMEKADRILIGGAMMFTFLKALGKEVGSSRVEEDKIDLAKELLEKAKEKGVEIVLPVDAVIAQKIEPGVEKKVVRIDDGIPEGWMGLDIGPETVELFKQKLSDAKTVVWNGPMGVFEIDDFAEGTKQVALAIAALTEKGAITVVGGGDSAAAVNKFGLEDKFSHVSTGGGASLEFLEGKELPGIASIADKKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNAG_BACSU
Sequence: MNVKKAAAVFSITIPIISAILIINFFTGFMSIPWQGMPVFFPLLLSPIGIILAFVSIKTNKRCAVYGIVLNAIMFPFPFFWFIGGALLFGV
What are the official names of this protein?
Uncharacterized protein YnaG.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR5_ECO81
Sequence: MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVNTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPLADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQWPEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIKASDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IN80B_MOUSE
Sequence: MSACVPTVSSPLPLQDPMSKLWRRGSTSGAMEAPEPGETLELSLAGAHGHGVHKKKHKKHKKKHKKKHHQEEEAGPTLQTPAKPQLKLKIKLGGQVLGTKSVPTFTVIPEGPRSPSPLMVVDNEEEPMEGVPLEQYRAWLDEDSNLSPSPLRDLPGDLEGQEEEEEQRWLDALEKGELDDNGDLKKEINERLLTARQRALLQKARSQPSPTLPLPVGGGCPAPALTEEMLLKREERARKRRLQAARRAEEHKNQTIERLTKTAAPSGRGGRGAARGERRGGRAAAPAPAPMVRYCSGAQGSTLSFPPGVPTPTAVAQRPAPSGPAPRCSVPGCPHPRRYACSRTGQALCSLQCYRINLQLRLGGPEGPGSPLLAT
What is the function of this protein?
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
What are the official names of this protein?
INO80 complex subunit B, High mobility group AT-hook 1-like 4, PAP-1-associated protein 1, PAPA-1, Zinc finger HIT domain-containing protein 4.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: GAPT_MOUSE
Sequence: MLECFESSPVAVAVGVSLLVLLLLCGIGCAWHWNRRESTPFTLPKFMQRRSSRQKDVTKTVSSSAYVISPSMKASVESKGHKSTAKRNKMHGNYENVEVCPPCTEGTTEKALYENTQPSNLEEHVYGNQTDPLYYNFQKPSPPPPQDDDIYILPDCD
What is the function of this protein?
Negatively regulates B-cell proliferation following stimulation through the B-cell receptor.  May play an important role in maintenance of marginal zone (MZ) B-cells.
What are the official names of this protein?
Protein GAPT, Growth factor receptor-bound protein 2-binding adapter protein, transmembrane.
What is the protein family that this protein belongs to?
Belongs to the GAPT family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: WNTG_DROME
Sequence: MDISYIFVICLMALCSGGSSLSQVEGKQKSGRGRGSMWWGIAKVGEPNNITPIMYMDPAIHSTLRRKQRRLVRDNPGVLGALVKGANLAISECQHQFRNRRWNCSTRNFSRGKNLFGKIVDRGCRETSFIYAITSAAVTHSIARACSEGTIESCTCDYSHQSRSPQANHQAGSVAGVRDWEWGGCSDNIGFGFKFSREFVDTGERGRNLREKMNLHNNEAGRAHVQAEMRQECKCHGMSGSCTVKTCWMRLANFRVIGDNLKARFDGATRVQVTNSLRATNALAPVSPNAAGSNSVGSNGLIIPQSGLVYGEEEERMLNDHMPDILLENSHPISKIHHPNMPSPNSLPQAGQRGGRNGRRQGRKHNRYHFQLNPHNPEHKPPGSKDLVYLEPSPSFCEKNLRQGILGTHGRQCNETSLGVDGCGLMCCGRGYRRDEVVVVERCACTFHWCCEVKCKLCRTKKVIYTCL
What is the function of this protein?
Binds as a ligand to a family of frizzled seven-transmembrane receptors and acts through a cascade of genes on the nucleus.  Segment polarity protein.  May be a growth factor.  Acts on neighboring cells to regulate at least one gene, the homeobox segmentation gene engrailed.  Wg signal represses arm phosphorylation.  Wg signaling operates by inactivating the sgg repression of engrailed autoactivation.  Wg and Wnt2 have a role in the developing trachea and together are responsible for all dorsal trunk formation.  Wg also acts in the developing epidermis.  Acts as a morphogen, and diffuses long distances despite its lipidation.  Lipophorin is required for diffusion, probably by acting as vehicle for its movement, explaining how it can spread over long distances despite its lipidation.  In non-neuronal cells, wls directs wg secretion via clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps26 and Vps35) to sustain a wls traffic loop encompassing the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi.  In neuronal cells (the larval motorneuron NMJ), wg signal moves across the synapse through the release of wls-containing exosome-like vesicles.
What are the official names of this protein?
Protein wingless, Protein Wnt-1, Protein int-1, dInt-1, dWnt-1.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted. Synapse. Membrane; Lipid-anchor. Secreted, extracellular space, extracellular matrix. Note=Palmitoleoylation converts wg into a membrane-anchored protein that is partitioned into specialized lipid raft microdomains before secretion (PubMed:15166250). In the wing imaginal disK epithelium, the protein is produced in the apical region of the cell and undergoes transcytosis to the basolateral surface to be released in the extracellular space (PubMed:26974662). Possibly associated with the extracellular matrix (PubMed:15166250).
Protein: TEX9_HUMAN
Sequence: MAGRSLCLTRSSVPGTPFPPPVQQPSTPGPDLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEEFMKALEWGNS
What are the official names of this protein?
Testis-expressed protein 9.
Protein: Y2130_STAAN
Sequence: MLYPIFIFILAGLCEIGGGYLIWLWLREGQSSLVGLIGGAILMLYGVIATFQSFPSFGRVYAAYGGVFIIMSLIFAMVVDKQMPDKYDVIGAIICIVGVLVMLLPSRA
What are the official names of this protein?
UPF0060 membrane protein SA2130.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPOG1_HUMAN
Sequence: MSRLLWRKVAGATVGPGPVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVLSSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGPAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDTQPSYHHGNGPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLEKRSQPGP
What is the function of this protein?
Involved in the replication of mitochondrial DNA.  Associates with mitochondrial DNA.
What are the official names of this protein?
DNA polymerase subunit gamma-1, Mitochondrial DNA polymerase catalytic subunit, PolG-alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: MURD_STRAW
Sequence: MTNWQGKNVTVAGLGVSGIPAARVLHGLGAVVTVVNDGDDERSRAQAADLEALGITVRLGDGATLPEGTELIVTTPGWQPDKPLFAAAAEAGVPVWGDVELAWRLRGPGSAPWLAVTGTNGKTTTVQMLASILTAAGLRTAAVGNIGVSLLDAVLGEETYDVLAVELSSYQLHWAPSLRAHSATVLNIAPDHLDWHGSMEAYTADKGRIYEGNRVACVYNVADKATEDLVRAADVEEGCRAVGFTLGTPGPSQLGVVEGILVDRAFVEDRQKNAQELAEVADVHPPAPHNIANALAAAALARAFGVPASAVRDGLRAFRPDAHRIAHVADVDGVTYIDDSKATNTHAAEASLAAYGSIVWIAGGLAKGASFDELVAKSAQRLRGVVLIGADRALIREALARHAPEVPVVDLDRTDTGAMPAAVQEARRLAVAGDTVLLAPACASMDMFANYNKRGDAFAEAVRGLGA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOA1_BOTFB
Sequence: MVRVAVAGGTGGVGYAIVDALKAQTEHEFIVLSRTESPEYAAKNNVKVVSIDYSDVSQISKILDEHHIHTVISALCIVSKEHSDSQLNLVRGAAGSQSVKRFVPSEYGSAYEEKHALARPSTGLKAVAVKELAKTHLEYTSFVNGLFLDYLCMPTVPSHLAAGIRFFDIPSRTSVGIGSGTVPLVMTHTRDVGRFVVASLSLPKWENRSFIVGDRQSWHDVINIAGKITGEKWPSLRPSKSSGSHEPAHRAAYSASLKEHGDWFESGTFSSTLSSGSVYLNELFPEIIPSYGRRWPQDFD
What is the function of this protein?
Oxidoreductase; part of the gene cluster A that mediates the biosynthesis of botcinic acid and its botcinin derivatives, acetate-derived polyketides that contribute to virulence when combined with the sesquiterpene botrydial (PubMed:18208491, PubMed:21722295).  Botcinic acid and its derivatives have been shown to induce chlorosis and necrosis during host plant infection, but also have antifungal activities (PubMed:18208491, PubMed:21722295).  Two polyketide synthases, BOA6 and BOA9, are involved in the biosynthesis of botcinins.  BOA6 mediates the formation of the per-methylated tetraketide core by condensation of four units of malonyl-CoA with one unit of acetyl-CoA, which would be methylated in activated methylene groups to yield a bicyclic acid intermediate that could then either be converted to botrylactone derivatives or lose the starter acetate unit through a retro-Claisen type C-C bond cleavage to yield botcinin derivatives (PubMed:23203902).  The second polyketide synthase, BOA9, is probably required for the biosynthesis of the tetraketide side chain of botcinins (Probable).  The methyltransferase (MT) domain within BOA6 is probably responsible for the incorporation of four methyl groups (Probable).  The trans-enoyl reductase BOA5 might take over the enoyl reductase function of BOA6 that misses an ER domain (Probable).  The monooxygenases BOA2, BOA3 and BOA4 might be involved in further hydroxylations at C4, C5 and C8, whereas BOA7, close to BOA9, could potentially be involved in the hydroxylation at C4 in the side chain of botcinins (Probable).
What are the official names of this protein?
Oxidoreductase BOA1, Botcinic acid biosynthesis cluster A protein 1.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: PUR7_YERPG
Sequence: MQKLAELYRGKAKTVYTTENPDLLVLEFRNDTSALDGQRIEQFDRKGMVNNKFNHFIMTKLEEAGIPTQMERLLSDTEVLVKKLEMIPVECVIRNRAAGSLVKRLGIEEGLSLNPPLFDLFLKNDAMHDPMVNESYCKTFGWATEAQLARMKELSYLANDVLSKLFDDAGLILVDFKLEFGLFNGEVVLGDEFSPDGSRLWDKKTLNKMDKDRYRQSLGGLIEAYEEVAHRIGVKLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SYE2_ANAMM
Sequence: MRVITRFAPSPTGSLHLGGARTALFNWLFARRHGGQFLLRMEDTDQERSSETVAQSIIEDMAWLGLHHDQDVVIQSARRERHTQVAEELLARGKAYYCYCSEDDIAAEKLRHENEGKHYRHHCPSRDANHAQSGTAGVLRLKSPENREIKFTDGVYGEISVSSEQIDDMVILRSNGHPTYLLAVVVDDHDMCITHIIRGSDHITNTIKQMLLAEAMGWDNPQFCHIPLIHDEGGAKLSKRNRAPGVHEYRELGFLPEAVCNYLLRMGWSHKDEEIITMQSATQLFSIEKIGTSHSCLDSKKLLFLNHHYMNQKTELEILGLLLPFLEQELGHTVAETKLARLSLGVKKLMERAKTLADLARDSVFYVQNIPISVDDDAKQVILKSSELLAKLVGAMSQIEPKTWTKDFLSSYIKEWTKSNDVVISDVYHLLRAAIAGRLSTPSISEVMEILGQEECISRLRFFLNS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_GRABC
Sequence: MNELMKILGQGGQSLSFDQIKIQMASPEQIRSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKFRGIVCEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRIGLMVDLTLKELEKILYFENYVVLEPGLTDLKLHQLLTEEQLLNKQDEFGDDAFRAGIGAEAIKSVLEGIDIDEDKVRLRAELKETTSETKRKKLVKRLKLIEAFAESGAKPEWMILDVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQESVDALFDNGRRGRAITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPEMKLHQCGLPKKMALELFKPFIYSKLEKYGHATTIKAAKRMVEKERPEVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVTTAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILSPANGKPIIVPSQDIVLGLYYLSLETPEFRNTPDDKAQAFGTLGEIEAALHARTVTLHTKIRARLHTVDDQGSPIRVRVVTTPGRMLIAQILPRHPNVPFALINKQLTKKNVSDVIDAVYRHCGQKECVIFADRLMGLGFGQAAKAGISFGKDDLIIPAEKQEMIEKTAGEVKEFEQQYQDGLITAGERYNKVVDAWSRCTDEVAGAMMKEISKQELGRPINSVWMMSHSGARGSPAQMRQLAGMRGLMAKPSGEIIEQPIIANFKEGLSVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIIVENDCGTERGLTVRAVMDGGEVVSSLSERILGRTLSEDVLDPTTNKILYPRNTLIEEEHAEKIEKAGIEVVKIRSVLTCESTVGVCGHCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQRGAEQSSVEASHDGIVTVKNRNVVLNSQNVAIVMSRNCEIVLADEKGRERARYRVPYGARLLTDEGAQVTRAQKLAEWDPYTLPIITERAGKVEYLDLLDGVTLVERMDEVTGLTSKVVVDYKQNARGVDLRPRLQLKDESGDVVRLSNNTDARYFLSPDSILSVENGAEVNAGDVLARIPREGSKTRDITGGLPRVAELFEARRPKDHAVIAETDGRVEFGKDYKAKRRIIVKNDETGEETEYLIPKGKHVSVQEGDFVRLGDPLVDGPRVPHDILKVLGVEALSDYLVNEIQDVYRLQGVKINDKHIEVIVRQMLQKVEILDPGDTMYLIGEQVDRLEFEAENRKREREGERPAVAMPVLQGITKASLQTQSFISAASFQETTRVLTEAATAGKVDTLNGLKENVIVGRLIPAGTGSVMNRLRRIASGQDEAKGVGQETPRLSGQEAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.