PharMolix/UniProtQA huggingface dataset:
Protein: TX11A_ETHRU
Sequence: MEIHSNIILLLLIALFAIFVKMEDEEKPPNLTRMPEGVNFACSGKKPGFYADEGFDCQVYHMCSPEGQLTTYLCGPGTIFNQKKLVCDLPTNYNCADAAKDAEEANANVFKTQSSTSEP
What are the official names of this protein?
U-scoloptoxin(01)-Er1a, U-SLPTX(01)-Er1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-01 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURA_THEFY
Sequence: MGQEVRYRVRGGHALHGTAFIQGAKNAVLPMIGAALLASKGRTVLRNVPVIEDVRRALELAEYVGAKVEFHEAERTIVIDATGLNDPNRAVLPASIASRFRGSVLFIPALMHRMGRARIEGVGGCNLGSRNLDFHYRGFARLGAEVTEDPERKHINVKADNLKGGRLYLDTPSHTGTENLIMAAALTPGTTVIEHAALEPEVLDVIEFLGSMGAKISGGGTGFIKVEGVSELTAVEHTVMPDRIDTGVFAMMTAATGGDVSLVGANLDHLGVARWKLEQMGVQFTQQGAVLRVRRDPNVPLRPINAVTSPFPGFATDLQPPLMALATLAEGESYIREAIFDGRFALADELNKMGAKIEVEGNRAIVHGPSELHGTKVTAHDLRCGAGAIMAGLVAKGETIVSPAYQVDRGHSHFATRLSALGADVVREEVS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_ACIBS
Sequence: MTVQTFIPNGAKAASENTVTQPTHTTDVSIKKLYIETQGCQMNEYDSHRMADLLGDSHGYVLTNNPNEADILLMNTCSIREKAQEKVFSELGRWRKLKEQNPDLVIGVGGCVASQEGDNIQKRAPYVDMIFGPQTLHRLPQMLDQHHAQVEKPKKEKIKLVDISFPDIEKFDFLPEPRVEGFKAFVSIMEGCSKYCSFCVVPYTRGEEVSRPLDDVLAEIAGLAEKGVREISLLGQNVNGYRGETFEGGICTFPELLRLVAEIPGIGRLRYTTSHPLEFSDELIQCYEDLPQMVSHLHLPVQSGSNDVLKAMKRNHTIDVYIDKIAKLRKIRPDMHLSSDFIIGFPGETDENFAETLQFIKDLGFDHSYSFVYSKRPGTPASDLPDTTPEHVKKERLAQVQQVIKQSSIEKTDAMLGKIERVLIEKVSDQDPNILVGTADNTRLVTFVGDASRVGRFAEIEITEIKTLNLVYGELLNLEPDVA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_LEPBL
Sequence: MELPRLENVDLSGKRVFLRVDFNVPIENGKVTDKTRIEKTLPTIELLIKKGARIIIASHLGRPKGQTNPEFSLAPVVEVFKGLVKSNVYFSKTVIGDEPIKLSKELRDGEILVIENVRFHKEEEENEPGFSKKLAALADVYVNDAFGAAHRAHASTEGIAHLLPAYAGLLMHKEIVELSALLAKPARPFVAIIGGSKVSSKIKVLNNLFDKVNHLLIGGGMAYTFLKSRAVPVGNSLVEKDFEVQAFQLIEKAGVAGVDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTVSNYEKIIKNAGTIFWNGPMGVFEMDKFTGGTMAIAKAISKSKAKTVVGGGDSIAAINKAKVADKITHISTGGGASLEFMEGRKLPGVEALKKKVSE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_HISS2
Sequence: MSMQDTFSSPEHFTVLLREAVGGLALKENGIYIDGTFGRGGHSRFILSQLSKKGQLIAIDRDPQAIQVAQNIQDPRFRIVHDSFSAIPDICEKLGLTGKIDGILLDLGVSSPQLDNAERGFSFMKDGPLDMRMDTTQGLSATEWLRQVSEQDLAWVLKTFGEERFAKRIAQAIVGYNKSAVQSGAEPLNRTLQLAELIAQSVPFKDKYKHPATRSFQAIRIFINSELDELEKVLNGALNVLAPQGRLSIISFHSLEDRMVKHFIRKQSKGDDLPKGLPLREEQIQHNQKLKPVGKAIMPTEQEMAANVRSRSAVLRIAERI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETG_SOLTU
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MNMG_RHILO
Sequence: MTDHYDVVVVGGGHAGCEAASAAARAGAKTALVTLRFDTIGVMSCNPAIGGLGKGHLVREIDAMDGLMGRVADAAGIQFRLLNRRKGPAVRGPRTQADRKLYRLAMQEAIRQQNDLDVVEGEVLDFEINEGRITAVLLAGGRRLACGAVVLTTGTFLRGLIHIGEKKIVAGRMNEQASLGLSATMDRAGFKLGRLKTGTPPRLDGKTIDWASLESQAADEDPVPFSLMSDRITTPQIECGITRTTSATHELIRANLGRSAMYSGSIEGVGPRYCPSIEDKIVKFGDRDGHQIFLEPEGLDDDTVYPNGISTSLPQDVQLEILKTIPGLERATMLQPGYAIEYDHVDPRELHQTLETKRIAGLFLAGQINGTTGYEEAAGQGLLAGLNAARRAAGGEQIVLSRTEAYIGVMVDDLTSRGISEPYRMFTSRAEFRLSLRADNADERLTPLAAKLGIASVQRMQRYGDVMQRLDAARELARSVAMTPNEAARQGLEINRDGVRRSGYELLAYPDVDVAWLARVEPKFAAIDAKTAERLETEAKYSVYLDRQKSDVAQIRHEESRLIPETVDFAGVPGLSNELKQKMQARRPRSIADAQRMEGMTPAALAIIVAHVRHYENAQRDVA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACL7B_BOVIN
Sequence: MATRNSSSPKPMGTAQGDPGEAGTLPGPDAGIRDTSSATQLKMKPKKVRKIKALITDLGSQYCKCGYAGEPRPTYFISSTVGKRYSEAADSGDTRKETYVGHELLNMEAPLKLINPLKYGIVVDWDCIQSIWEYIFHTAMKILPEEHAVLVSDPPLSPTSNREKYAELLFETFGIPAMHVTSQSLLSIYSYGKTSGLVVESGHGVSHVVPISEGDVLPGLTSRADYAGGDLTNYLLQLLNEAGHKFTDDHLHIIEHIKKKCCYSALKPEEELSLCLEDLRVDYELPDGKLISIGQERFQCAEMLFKPTLVGSNQPGLPELTAACLNRCQEAGFKEEMAANVLLCGGCTMLDGFPERFQRELSLLCPGDSPAVAAAPERKTSVWTGGSILASLQAFQQLWVSKEEFEERGSAAIYSKC
What are the official names of this protein?
Actin-like protein 7B.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AK_CORFL
Sequence: MALVVQKYGGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLELAAAVNPVPPAREMDMLLTAGERISNALVAMAIESLGAEAQSFTGSQAGVLTTERHGNARIVDVTPGRVREALDEGKICIVAGFQGVNKETRDVTTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLSFEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPVEEAVLTGVATDKSEAKVTVLGISDKPGEAAKVFRALADAEINIDMVLQNVSSVEDGTTDITFTCPRADGRRAMEILKKLQVQGNWTNVLYDDQVDKVSLVGAGMKSHPGVTAEFMEALRDVNVNIELISTSEIRISVLIREDDLDAAARALHEQFQLGGEDEAVVYAGTGR
What is the function of this protein?
Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.
What are the official names of this protein?
Aspartokinase, Aspartate kinase.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: YCGL_ECO57
Sequence: MPKPGILKSKSMFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMILPLDGRKKLVNADIEKVKQALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK
What are the official names of this protein?
Protein YcgL.
Protein: DUT_BURO1
Sequence: MKLDLKILDARMRDYLPAYATTGSAGLDLRACLDAPVTLQPGETTLVPTGLAIHLADPGYAALILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSTWNRGQTAFVLNPFERLAQLVIVPVVQAQFNIVDEFTESDRGEGGFGSTGRH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: EFTU_STAA8
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVAQSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATA_STAEQ
Sequence: MSKQDGKLTGLFGAPVSDRENSMTAGQRGPLLMQDVYYLEQISHFDREVIPERRMHAKGSGAFGTFTVTNDITQYTNAKIFSEVGKQTEMFARFSTVSGERGAADLERDIRGFALKFYTEDGNWDLVGNNTPVFFFRDPKLFISLNRAVKRDPRTNMRSAQNNWDFWTGLPEALHQVTILMSDRGMPKGFRNMHGFGSHTYSMYNDKGERVWVKYHFRTQQGIENYTDEEAAKIVGMDRDSSQRDLYNAIENGDYPKWKMYIQVMTEEQAKNHPDNPFDLTKVWYKKDYPLIEVGEFELNRNPENYFLDVEQAAFTPTNIVPGLDYSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQPKGVGVENLCPFSRDGQMRFLDNNQGGGPHYYPNNQGIYESQPEHKKPPFPTDGDGYEYNYRQDDDNYFEQPGKLFRLQSEDAKERIFTNTANAMDGVSKDVKVRHIRHCYKADPEYGKGVAKALGIDINQIDLETNQDETYENFK
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: CLPX_BURPS
Sequence: MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEASLSKSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQVDTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLREVEPEDLIKFGLIPELIGRLPVVATLGKLDEAALMKILVEPKNALVKQYQKLFAMERVELEIRPDALQAVARKAIRRKTGARGLRSIIEQALLDVMYELPTLKGVSKVIIDDNVIEGDGKPLLIYEDTPKVAGSN
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: HEM3_SHESW
Sequence: MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKGLFVKELEVAILEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNIYKTISELPLGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLSGRIASFISAEQSLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEGGCQVPIGAFAEINGDEMTLRGLVGNPDGSEIIEGIITGPKTEATQLGVALAEELLSKGAKSILDAVYAKA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: F13A_BOVIN
Sequence: MSESSGTAFGGRRAIPPNTSNAAENDPPTVELQGLVPRGFNPQDYLNVTNVHLFKERWDSNKVDHHTDKYSNDKLIVRRGQSFYIQIDFNRPYDPTRDLFRVEYVIGLYPQENKGTYIPVPLVSELQSGKWGAKVVMREDRSVRLSVQSSADCIVGKFRMYVAVWTPYGVIRTSRNPETDTYILFNPWCEEDAVYLEN
What is the function of this protein?
Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot.  Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
What are the official names of this protein?
Coagulation factor XIII A chain, Coagulation factor XIIIa, Protein-glutamine gamma-glutamyltransferase A chain, Transglutaminase A chain.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
Protein: IF2G_AERPE
Sequence: MSGGDKRQPEVNIGVVGHVDHGKTTLVQALTGVWTMRHSEEIRRGMTIKLGYADGEVWECEGCGFPERFSPEPVCECDPQASASLRRRVSYVDAPGHEILMATMLSGAALMDGALLVVAANEPCPQPQTKEHLVALEIIGIKNIVIVQNKVDVVSRERAKESYQEILNFIKGTIAEGSPIIPVSALKRANIDAVLAAIEKFIPTPPRDLDKPPVMYISRSFDVNRPGTPPERLVGGVVGGSIIQGVFRVGDEIEISPGVAVRKPGGRVEYVRLHTTITSLRFGSIEVEEARPGGLVAIGTQLDPSVTKADNLVGNVVGKPGELPEPLTTLRIEHHLLEKVVGMKEEARVEPIRRGEMLMLSVGTAITLGVVTRAGKDEIEVQLRRPVVTWPKARVALSRRIMGRWRLIGWGLIK
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit gamma, aIF2-gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: C2D4D_HUMAN
Sequence: MWLLEKAGYKVGAAEPAARWAPSGLFSKRRAPGPPTSACPNVLTPDRIPQFFIPPRLPDPGGAVPAARRHVAGRGLPATCSLPHLAGREGWAFLPESPHTRRRESLFHGPPPAPAGGLPAAQSRLHVSAPDLRLCRAPDSDTASSPDSSPFGSPRPGLGRRRVSRPHSLSPEKASSADTSPHSPRRAGPPTPPLFHLDFLCCQLRPTRESVLRLGPRGGQLRLSTEYQAGPGRLRLRLVSAEGLPRPRSRPGSGGGGCCVVLRLRPRVRPREQQSRVVKCSANPIFNEDFFFDGLGPPDLAARSLRAKVLDRGAGLRRDVLLGECETPLIALLPPLGGGLGPGSSLAPTHLSL
What are the official names of this protein?
C2 calcium-dependent domain-containing protein 4D.
Protein: EGR2_CRIGR
Sequence: AEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGR
What is the function of this protein?
E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 transcriptional activity.
What are the official names of this protein?
E3 SUMO-protein ligase EGR2, E3 SUMO-protein transferase ERG2, Early growth response protein 2, EGR-2, Zinc finger protein Krox-20.
What is the protein family that this protein belongs to?
Belongs to the EGR C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS21_RAT
Sequence: MQNDAGEFVDLYVPRKCSASNRIIAAKDHASIQMNVAEVDRSTGRFNGQFKTYGICGAIRRMGESDDSILRLAKADGIVSKNF
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: NP214_ARATH
Sequence: MSRVEIEEDTEGDRISTNDYYFERIGEPISIKEDDAQYDLENPPSQPLAISERHAVLFVAHSSGFFVGRTNDVISASKNSNGNGDKVFIQDLSLVDVPVGDVRILSLSADDSILAVTVAADIHFFSVDSLLKKDAKPSFSYSPDESGFVKDFRWRRNDKHSYLVLSNTGKLFHGIDNAPPRHVMDAVDAVEWSSKGSYIAVAQDNSLRIFSSKFNEKRCIALSFDSWIGDSDEDCFVKVDSIRWVRNNCILLGCFQLIEGREENYLVQVIRSPDGKISDGSTNLVALSFSDLFPCSMDDLVPVGVGPHLLFSYIDQCKLAVTANRKSIDEHIVLLDWSSGDDKSAVSVVDIDRETFLPRIGLQENNDDNTVMGLCIDRVSIEGTVNVRSGDDELKELQPYFVLVCLTLEGKLVMFNVASVAGRPASSDTDLASSSDIEDAYTPLIEDDLSKQSSEKHQQLNIAVQNDQKHLNTEKFSTEQRLPNENIFSKEFESVKSSVSGDNNKKQEPYAEKPLQVEDAQQSMIPRLSGTSFGQLPMSLGYDTNKFAGFGPALPVSEKLQKDIFAQSNSMHLQANVESKSTAAFFGSPGLQNAILQSPQNTSSQPWSSGKSVSPPDFVSGPFPSMRDTQHKQSVQSGTGYVNPPMSIKDKSVQVIETGRVSALSNLSPLLGQNQDTNEGVEKIEPIPSIRASQLSQQVKSSFEKSASHQQHKTPLSTGPLRLEHNMSNQPSNINEMAREMDTLLQSIEGPGGFKDSCAFILKSNVEELEQGLESLAGKCQTWKSTIHEQQAEIQHLLDKTIQVLAKKTYMEGMYKQTADNQYWQLWNRQKLNPELEAKRQHIMKLNKDLTHQLIELERYFNRLELDRYNEDGGHPVARRGVPNRSAPSRRVQSLHSLHNTMSSQLAAAEQLSECLSKQMTYLKIDSPVKKNVKQELFETIGIPYDASFSSPDAVKAKNASSAKNLLLSSIPASINQQSRQRQSSAMKNSDPETARRRRESLDRVIFNWAAFEPPKTTVKRMLLQEQQKTGMNQQTVLSERLRSANNTQDRSLLHVKDHASPVVSSNKGIMESFQQDTSEAQSTPFKTRPPMPQSNSPFTISPISASKPSFNWSGNKSSNTTSYAEESAPSQIKDTRTVSQPGGSSFLPKRPVASTVLEQTEKKAGEFKFSEAKANAFVETAAGSVQRLSTTSSGSDFESSKGFGAQFSTMSSGAPASSFSSKSLFGFNSSSSIPGDKFTFPAVTAPLSGTPLDSTSTLFTASSAPVSSSSQDPVPASIPISSAPVPQTFSVTSTSTVSATGFNVPFGKPLTSVKVDLNQAAPSTPSPSPGPTAGFTFNLPALSPSSPEMVSSSTGQSSLFPPSAPTSQVSSDQASATSSLTDSSRLFSSTSLSSTPPITPPDAFQSPQVSTPSSAVPITEPVSEPKKPEAQSSSILSTQSTVDSVANATKTQNEPLPVKSEISNPGTTVTPVSSSGFLSGFSSGTQSSLASMAAPSFSWPGSSQPQQLSSTPAPFPASSPTSASPFGEKKDIVDTQEDEMDEEAPEASQTTELSMGSFGGFGLGSTPNPGAPKTNPFGGPFGNATTTTSNPFNMTVPSGELFKPASFNFQNPQPSQPAGFGSFSVTPSQTPAQSGFGQPSQIGGGQQALGSVLGSFGQSRQIGAGLPGATFGSPTGFGGSNPGSGLPNAPASGGFAAAGSSATGGFAAMASAGRGFAGASSTPTGGFAALASGSGGFAGAAPGGGGGGFGGLGSGTGGFGGFAPQGSSGGFAGAAGGGGFGGFGGQAQGQAGGGGFSAFGGNSGATGKPSELFTQMRK
What is the function of this protein?
Required for normal embryogenesis and seed viability.  Involved in the first asymmetrical cell division of the zygote.  Regulates the number and planes of cell divisions required for generating the normal embryo proper and suspensor, apical-basal axis, cotyledons and meristem.
What are the official names of this protein?
Nuclear pore complex protein NUP214, Nucleoporin 214, Protein EMBRYO DEFECTIVE 1011, Protein LNO1, Protein LONO1.
What are the subcellular locations of this protein?
Nucleus envelope. Nucleus, nuclear pore complex.
Protein: ECFA2_STRR6
Sequence: MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGSGKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEETVLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGILAMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVMEKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKESLNG
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: END3_PODAN
Sequence: MAPRIEPQEIETYWNIFSTRTNGGQFLTGEMAAPVLKNSGLRDDQLERVWDLADVDNDGNLDFEEFCVAMRVIFDLLNGEYADVPKVLPDWLVPESKSHLVSANKAIRGQEPKMERVEDEEEEEGLKDGFDWYMSPEDKSRYEAVYREGRDMRGEINFEALSDLYNSLDVPDTDVRSAWNLINPNASQTINKDACLAFLHILNYRHEGYRIPRTVPASLRASFERNQIDYQVDNQAAKSRWATKADDETSTGRKAKFGDQYLTRLGRSGFTSKGTDFTTTKNSDAEWEEVRLKKQLQELEDKLARIEQGVEARKGGKRDSKPALVKRELEQLLDYKRKELRDLEEGKGKSRTGSNLKSVSEDLQTVREQVEGLESHLRSRQEVLEQLRREIEEEKISR
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein END3, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: C144A_HUMAN
Sequence: MASWGGEKRGGAEGSPKPAVYATRKTPSVGSQGDQWYLGYPGDQWSSGFPYSWWKNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHILAPGDTGVDKRDRKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVDDKCPSVSPSMPENQSATKELGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDSELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQRFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPFNLTNNIPGCEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSKFHLHENKLDCDNDNKPGIGHIFSTDKNFHNDASTKKARNPEVVMVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGLNQQIPRKENGEHDRPADKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKELYLEEVKVRESLSNELSRTNEMIAEVSTQLTVEKEQTRSRSLFTAYATRPVLESPCVGNLNDSEGLNRKHIPRKKRSALKDMESYLLKMQQKLQNDLTAEVAGSSQTGLHRIPQCSSFSSSSLHLLLCSICQPFFLILQLLLNMNLDPI
What is the function of this protein?
May play a role in preventing the formation of kidney stones through inhibition of calcium oxalate monohydrate (COM) crystallization, attenuating COM-induced apoptotic injury to renal epithelial cells (PubMed:32991878).  May exhibit antilithiatic (preventing the formation of kidney stones) activity through crystal binding, hindering the crystal attachment to renal epithelial cells, a pre-requisite to initiate inflammatory response (PubMed:32991878).
What are the official names of this protein?
Coiled-coil domain-containing protein 144A.
What is the protein family that this protein belongs to?
Belongs to the CCDC144 family.
Protein: BFSP1_HUMAN
Sequence: MYRRSYVFQTRKEQYEHADEASRAAEPERPADEGWAGATSLAALQGLGERVAAHVQRARALEQRHAGLRRQLDAFQRLGELAGPEDALARQVESNRQRVRDLEAERARLERQGTEAQRALDEFRSKYENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIETPIPLFTQSHGVSLSTGSGGKDLTRALQDITAAKPRQKALPKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESKEVSPLTQEGAPEDVPDGGQISKGFGKLYRKVKEKVRSPKEPETPTELYTKERHVLVTGDANYVDPRFYVSSITAKGGVAVSVAEDSVLYDGQVEPSPESPKPPLENGQVGLQEKEDGQPIDQQPIDKEIEPDGAELEGPEEKREGEERDEESRRPCAMVTPGAEEPSIPEPPKPAADQDGAEVLGTRSRSLPEKGPPKALAYKTVEVVESIEKISTESIQTYEETAVIVETMIGKTKSDKKKSGEKSS
What is the function of this protein?
Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA (PubMed:28935373).  Involved in altering the calcium regulation of MIP water permeability (PubMed:30790544).
What are the official names of this protein?
Filensin, Beaded filament structural protein 1, Lens fiber cell beaded-filament structural protein CP 115, CP115, Lens intermediate filament-like heavy, LIFL-H.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.