PharMolix/UniProtQA huggingface dataset:
Protein: POTD_SALTY
Sequence: MKKWSRHLLAAGALALGMSAAHASDNDTLYFYNWTEYVPPGLLEQFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKSKLTNFHNLDPEMLNKPFDPNNDYSVPYIWGATAIGVNSDAIDPKTITSWADLWKPEYKNSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYEELKKLMPNVAAFNSDNPANPYMEGEVNLGMVWNGSAFVARQAGTPLEVVWPKEGGIFWMDSLAIPANAKNKEGALKLINFLLRPDVAKEVAETIGYPTPNLAARKLLSPEVANDKSLYPDAQTISKGEWQNDVGDASAIYEEYYQKLKAGR
What is the function of this protein?
Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.  Polyamine binding protein.
What are the official names of this protein?
Spermidine/putrescine-binding periplasmic protein, SPBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein PotD/PotF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: COX8A_HYLAG
Sequence: MSVLTPLLLRGLTGSARRLPVPRAKIHSLPPEEKLGIMELAVGLTSCFVTFLLPAGWILSHLETYRRPE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8A, mitochondrial, Cytochrome c oxidase polypeptide VIII-liver/heart, Cytochrome c oxidase subunit 8-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: TRPA_GEOUR
Sequence: MSRIATTFANLAKQNEKALVTFITAGDPDLETTEKLILELEKSGADLIELGVPFSDPMADGPTIQLSSERALCAGTTLPKILTLVKSVRQQTEIPLILMGYYNPVFLYGIERFVADAVSAGVDGVLLVDLPPEEAEEFKAAADREGLDVIFLLTPTSDEARIRKVANLGSGFIYYVSVTGVTGARTSVADTVFPDVKKIREHVTLPLVVGFGISDPVQAGRVAAVADGVVVGSALVKLFEEFRGDELRERLGGFVAALKAGVKAVGG
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: P2OX_TRIMT
Sequence: MPIRLSKEKINDLLQRSQGDLTSSQDEIVHYTDVFIAGSGPIACTYARHIIDNTSTTKVYMAEIGSQDNPVIGAHHRNSIKFQKDTDKFVNIINGALQPISISPSDTYQPTLAVAAWAPPIDPAEGQLVIMGHNPNQEAGLNLPGSAVTRTVGGMATHWTCACPTPHDEERVNNPVDKQEFDALLERAKTLLNVHSDQYDDSIRQIVVKETLQQTLDASRGVTTLPLGVERRTDNPIYVTWTGADTVLGDVPKSPRFVLVTETRVTKFIVSETNPTQVVAALLRNLNTSNDELVVAQSFVIACGAVCTPQILWNSNIRPHALGRYLSEQSMTFCQIVLKRSIVDSIATDPRFAAKVEAHKKKHPDDVLPIPFHEPEPQVMIPYTSDFPWHVQVHRYAFGDVGPKADPRVVVDLRFFGKSDIVEENRVTFGPNPKLRDWEAGVTDTYGMPQPTFHVKRTNADGDRDQRMMNDMTNVANILGGYLPGSYPQFMAPGLAQHITGTTRIGTDDQTSVADPTSKVHNFDNLWVGGNGCIPDATACNPTRTSVAYALKGAEAVVSYLGVS
What is the function of this protein?
Catalyzes the oxidation of various aldopyranoses and disaccharides on carbon-2 to the corresponding 2-keto sugars concomitant with the reduction of O(2) to H(2)O(2).  The preferred substrate is D-glucose which is converted to 2-dehydro-D-glucose.  Acts also on D-xylose, L-sorbose, D-galactose and 1,5-anhydroglucitol, a diagnostic marker of diabetes mellitus.
What are the official names of this protein?
Pyranose 2-oxidase, P2Ox, POD, POx, PROD, Pyranose oxidase, FAD-oxidoreductase, Glucose 2-oxidase, Pyranose:oxygen 2-oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: RL7_BURPS
Sequence: MAIAKEDILAAVEGMTVLELNELVKAFEEKFGVSAAAVAVAGPAAGGAAAAAEEKTEFTVVLAEAGSNKVAVIKAVREITGLGLKEAKDLVDGAPKPVKEGVDKASADEAKKKLEDAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: KAE1_ASHGO
Sequence: MVNLNKVQPRSGGDHYLALGIEGSANKLGVGILKHPMLSQHKQGSLSHDCQAEILSNIRDTYITPPGEGFLPRDTARHHRNWVVRLVRRALVEAGIEDPRLLDVICFTKGPGMGAPLHSVVVAARTMSMLWDVPLVAVNHCIGHIEMGREITKAENPVVLYVSGGNTQVIAYSENRYRIFGETLDIAIGNCLDRFARTLKIPNDPSPGYNIEQLAKQCKNKDRLVELPYTVKGMDLSMSGILAHIDSLAKDLFRRNTKNYKLFDRETGKQLVTVEDLCYSLQEHLFAMLVEITERAMAHVNSNQVLIVGGVGCNVRLQQMMASMCQSRADGQVHATDERFCIDNGVMIAQAGLLQYRMGDIVKDFSETVVTQRFRTDEVYVSWRD
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1, tRNA threonylcarbamoyladenosine biosynthesis protein KAE1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RNPA_BIFA0
Sequence: MERLKNHREFVAVLKRRRRVSDADIVLHYVVRTPSTPTGAAPARRLGLAVSKSVGNAVVRNTVKRRFRVLAHRYEHELPADCDIVLRAKPGAAHASFQSLEAQIQALFRAVMRKSEQS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: VSR6_ARATH
Sequence: MSLIHKGATLALFLALTMVVNGVFGRFIVEKSSVTILNPLAMRSKHDAAIANFGVPNYGGYMIGSVVYAGQGAYGCDSFDKTFKPKFPRPTILIIDRGECYFALKVWNGQQSGVAAVLVADNVDEPLITMDSPEESKEADDFIEKLNIPSALIDFSFANTLKQALKKGEEVVLKIDWSESLPHPDERVEYELWTNTNDECGARCDEQMNFVKNFKGHAQILEKGGYSLFTPHYITWFCPKDYVSSNQCKSQCINQGRYCAPDPEQDFGDGYDGKDIVFENLRQLCVHKVAKENNRSWVWWDYVTDFHIRCSMKEKKYSKECAERVVESLGLPLDKIKKCIGDPDANVENEVLKAEQALQVGQGDRGDVTILPTLIVNNAQYRGKLERNAVLKAICSGFKERTEPGICLSGDIETNECLEANGGCWEDKKSNVTACKDTFRGRVCECPVVNGVQYKGDGYTSCEPYGPARCSINQGGCWSETKKGLTFSACSNLETSGCRCPPGFKGDGLKCEDIDECKEQSACQCDGCNCKNKWGGFECKCSGNRLYMKEQDTCIERSGSRIGWFPTFVILAAVASICVGGYVFYKYRLRSYMDSEIMAIMSQYMPLESQNTTDPMTGESQHQQLRLTSAA
What is the function of this protein?
Vacuolar-sorting receptor (VSR) involved in clathrin-coated vesicles sorting from Golgi apparatus to vacuoles.
What are the official names of this protein?
Vacuolar-sorting receptor 6, AtVSR6, BP80-like protein d, AtBP80d, Epidermal growth factor receptor-like protein 6, AtELP6.
What is the protein family that this protein belongs to?
Belongs to the VSR (BP-80) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein.
Protein: END4_KLEP3
Sequence: MKYVGAHVSASGGLANAAIRAAEIEATAFALFTKNQRQWRAAPLSDETIAEFKAACEKYHFGPGQILPHDSYLINLGHPVEEALEKSRDAFIDEMTRCQQLGLTLLNFHPGSHLQQIPEEACLARIAESINIALAKTEGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRSAEACEKTFADFERIVGFQYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDCFRWIMQDSRFNGIPLILETINPDIWAEEIAWLRAQQIAEVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: SN12L_HUMAN
Sequence: MDLARKEFLRGNGLAAGKMNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEALAADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVGLNEDKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEELPSPASTSSPVSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKDLEKALSNILPKENQIFLFVCLFRFCLFVCWFVCFFLR
What are the official names of this protein?
Schlafen family member 12-like.
What is the protein family that this protein belongs to?
Belongs to the Schlafen family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RNC_DESVM
Sequence: MFEKLQSDIHYAFNDAGLLATAMTHSSWANEQQEHVEHNERLEFLGDAVLELCVSEELFARFPGAREGDLTRMRARLVSKPALAELARDLQLELYLRLGRGEESQGGRERSSLLSDALEAMLGAVFLDGGYERARAVVRHVLAARWPCDADGKRSKDYKSRLQELTQSLFRERPVYALMGSSGPEHEKRFEVRLTLPDGTVFTAIGPSVKRAEQMAAGLALKNLESRSDG
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_CAUVC
Sequence: MNHFKTYMLLAGLTALFMGAGFLIGGATGMMIALVFALAMNAFSYWNADKIVLRTYGAVEVDESHPEPLIRNYVIDTVEMARSAGLPRPRITVIDSAQPNAFATGRDPDHAAVAASTGLLQLLTREEIRGVMAHELAHVKNRDTLVMTVTATIAGAISALANFAFFFGGSRDEEGNGGGLGGMIGAILIAILAPIAAMLVQMAISRAREYEADRIGAQIAGDSESLARALQKIEAYARGGYENVQAERNPATAHMFIINPLAGKGADNLFSTHPATHNRVEALMRLGVERGARRPVMAATTSSSVPLSGERGGPWS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TBA1_PNECA
Sequence: MREVISIHVGQAGTQIGNACWELYCLEHGIEPDGRLSPEKTTKPLDDGFSTFFSETGSGKYVPRSIYVDLEPNVIDQVRTGTYRHLFHPEQLITGKEDAANNYARGHYTVGKELIDHVLDRIRRVADNCTGLQGFLVFHSFGGGTGSGFGALLLERLSVDYGKKSKLEFSVYPAPQVSTSVVEPYNSILTTHTTLEHSDCSFMVDNEAIYDICRRNLDIERPGYENLNRLIAQVVSSITASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVTYAPLISAAKAHHEANSVAEITNACFEPNNQMVKCDPRNGKYMATCLLYRGDIVTKDVNCAVSSIRTKRTIQFVDWCPTGFKLGVCYQPPQYVPNGDLAKVNRAVCMLSNTTSIAEAWSRLDHKFDLMYSKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGQDSIEGEIMEEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FTSH_RICFE
Sequence: MNNQGRSILTWAALFVFVILLFNVFQSDGLLGGRNNITFSDFLTRVDEKTVNSVKIQGRVIEGTSNDGSTFNTYAPDYPDLVNRLTSNDVNIEVVPLETRMNTFLGFLISWFPMLLLIGVWVFFMRQMHGGGKAMGFGKSKARLLSDKGPKITFKDVAGIDEAKEELTEIVDFLRDPSKFQKLGGKIPKGCLLIGPPGTGKTLLAKAIAGEANVPFFSISGSDFVEMFVGVGASRVRDMFEQGKRNAPCIIFIDEIDAVGRHRGIGMGGGNDEREQTLNQMLVEMDGFEANEGVVIIAATNRPDVLDRALLRPGRFDRQIAVANPDINGREQILKVHLKKIKYNSTVLARIIARGTPGFSGAELANLVNEAALIAARLGKKEVDMHDMEEAKDKVLMGVARRSIAMSEKEKRLTAYHEGGHALVGLYCPAASPLHKATIIPRGNALGMVQRLPETDEYSQNREQMESSIAVYMAGRVAEEIIFGRNKVTSGASSDIKGATNIARAMVTKAGLSDLIGPIFHGSSSDDMYGRQPSNETSEATAELIDAEVKKIITQGYEFAKDILTKHIDQLHTLANALIEYETLSGQQIKNLLSGRALDSEEENKFPFNDSPTIKIDKEKSPEKAKKAKKESTNI
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: MNHE2_STAA8
Sequence: MNQIVLNIIIAFLWVLFQDEDHFKFSTFFSGYLIGLIVIYILHRFFSDDFYVRKIWVAIKFLGVYLYQLITSSISTINYILFKTKDMNPGLLSYETRLTSDWSITFLTILIIITPGSTVIRISQDSKKFFIHSIDVSEKEKDSLLRSIKHYEDLILEVSR
What are the official names of this protein?
Putative antiporter subunit mnhE2, Mrp complex subunit E2, Putative NADH-ubiquinone oxidoreductase subunit mnhE2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTRK3_HUMAN
Sequence: MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLFVMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG
What is the function of this protein?
Receptor tyrosine kinase involved in nervous system and probably heart development.  Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
What are the official names of this protein?
NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LSPA_OCEIH
Sequence: MIMYYLIAIALVIIDQLTKWLVVSRMELGESISVIDNFFYITSHRNTGAAWGILEGQMLLFYIITTIVIIGIIYFLHTHAKGDKLLSVALVVILGGAIGNFIDRIFRQEVVDFANFYIFDYNFPIFNVADSSLTIGVILFLIATILEEKRQKGKSKS
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS8_STRR6
Sequence: MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREGFVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLGIAILSTSEGLLTDKEARQKNVGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: KTHY_TRIV2
Sequence: MGGRFIVFEGVEGCGKTSQMQLCAEWLQNLGISVILTREPGGTELGVDLRRLLLQKAEDKPIAEVTELLLYAADRAQHVAQELKPKLAQGKYILCDRYVDSTIAYQGYGRNLDMNLIHQLNDIATGGLTSDITIWLDVDVEVGLARKRGENVGLDRIEQETIAFHRRVQQGYANLAASSPSRIIRVDGQLSKETVHKTIQEILSPHLKEWL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SURE_CITBB
Sequence: MKILLTNDDGVHSPGLAALIKKVSEVAEVVVVAPDREQSAVSHALTLHHPLRAARIGANVFSVEGTPTDCVNLGIHSLLSYRPDLVISGVNRGANIADDVTYSGTVAAALEATLMGIPAIAVSLVTRSAGEHFEAAAACAAKLAVTVHQKGLPRDTYLNVNVPDLPAESLLPPLITCQGKRSYEGTIVDKVDPRGRNYYWIGTTDLSFEDIPGTDYHAVSRGHVSISPLHIDLTNHASIEMLKSWELP
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_XANOM
Sequence: MLQPKRTKYRKMHKGRNDGLAWSGNAVSFGEYGLKATAHGQLTARQIEAARRTISRHVKKGGKMWIRVFPDKPITKKPIEVRMGSGKGNVEYWVAQIQPGRMIYEIEGIPEETAREAFRLAAAKLSVTTTFVTRTVR
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PFD6_MOUSE
Sequence: MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQAAKAPGKA
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
What are the official names of this protein?
Prefoldin subunit 6, Protein Ke2.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: QMCA_SHIFL
Sequence: MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIRDVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSANKRTQP
What are the official names of this protein?
Protein QmcA.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PCP_BACAH
Sequence: MKTVLLTGFDPFGGESINPAWEVAKSLHEKTIGEYKIISKQVPTVFHKSISVLKEYIEELAPEFIICIGQAGGRTDITIERVAINIDDARIADNEGNQPVDVPVVEEGPAAYWSTLPMKAIVKKLQEEGIPASVSQTAGTFVCNHLFYGLMHELEKHDTKMKGGFIHIPFLPEQASNYPGQPSMSLSTIRKGIELAVEVTTTVEVDIVEIGGTTH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C99L2_BOVIN
Sequence: MVAWRWACLICLAFSLTTLVQRGSGDTGGFRLEDAVEGTSSVKQRWDHVTTTTRRPGATRAPAKPAGPPAEDDFNLADALDDQNDRDHDRKKPSIGGGGFSDKDLEDIVGGGDYKPDKGKGGGQYGGGDNSDDSGMSAETGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEPQVKYSALQTQSTEPPPPEPPRI
What is the function of this protein?
Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane.  Acts at the same site as, but independently of, PECAM1 (By similarity).  Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity).
What are the official names of this protein?
CD99 antigen-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the CD99 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein; Extracellular side. Cell junction.
Protein: NADK_FRATT
Sequence: MTFKYHKVAIVGKHYKKEVSQMVETLYAYLQQQGLEIIIENDTAADTSLVNVAIASLKEIALRCDVAIVVGGDGNFLKASRLLALYSNIPVIGINKGKLGFLTTLAADDNALKNDLYAILKGDSSVTKMSMLKYRVDNNLRAPLEASIALNEIAITASRGLMFGLKVFIDGRYAFDQRGDGLIVSTPTGSTAHAMSAGGPILNPNQNSVVLVPICSHSLNSRPLVISDESVIDIYITDYNDPESVLSIDGRHDTILKAHQKVTIQKARKKVTVLHTKDYNYYDTLREKLGWSKVLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_LISMO
Sequence: MNDRQAALDQALKQIEKQFGKGSIMKLGEHSDQNISTISSGSLALDIALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQAQGGTAAFIDAEHALDPAYAKNLGVNIDELLLSQPDTGEQALEIAEALVRSGAVDMLVIDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLSGVINKSKTIAIFINQIREKVGVMFGNPEITPGGRALKFYSTVRLEVRRAEQLKQGTDVMGNKTKIKVVKNKVAPPFRIAEVDIMYGEGISREGELVDMAAEVDVINKSGSWYSYKEERIGQGRENAKQYLKEHTDIRDEISKRVREEYEIDGSSKEPLDEKEETLSLLDDE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.