PharMolix/UniProtQA huggingface dataset:
Protein: DCD_HELPG
Sequence: MGLKADSWIKKMSLEHGMISPFCEKQVGKNVISYGLSSYGYDIRVGSEFMLFDNKNALIDPKNFDPNNATKIDASKEGFFILPANAFALAHTIEYFKMPKDTLAICLGKSTYARCGIIVNVTPFEPEFEGYITIEISNTTNLPAKVYANEGIAQVVFLQGDEMCEQSYKDRGGKYQGQVGITLPKILK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: TRMB_LACP3
Sequence: MRLRNKQWAKPLILAHPEMILVRPEKMQGHWQSRFDQARPLYLEVGSGKGQFIVEMAKTHPDRNFIALELQEAAVAMILKKQVALKLPNLQLVLGDGADLTDYFSEGEIDGLFLNFSDPWPKTRHEKRRLTYRDFLRQYQAIMKPDALLQFKTDNQGLFEYSLVSMNHFGMTFDLVSLNLHHDKRVTDNVPTEYEEKFSADGGRIYELVAHFKH
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RSMF_SHEB2
Sequence: MVQLNQNFIDTITQELPAHLSMDEFIAACDRPLRRSIRVNTLKISSDDFKTLMQPKGWTFDPIPWCEDGFWISYDEEEQLGNALEHIQGLFYIQEASSMLPPTALFTPSAFTTSAKWQCVLDLASAPGSKTTQMAALMQNQGLLVANEYSASRVKVLHANVLRMGASHCALTHFDGRVFGEYLYESFDAVLIDAPCGGEGTVRKDVDALKHWSLDDVLAISETQKALIESAFLALKPGGSLVYSTCTLNRLENQGVCEYLKQVYGDAVQFESLSDLFDGAERATTAEGFLHVWPQIYDSEGFFVAKLTKTASVPRLQPEPKLQKNFPFTPASAKQAQGIKDYFQQDLGISLPDELIMVRDDEFWLFPHEFNAFIGRMRFQRIGIKLADSSKHGFKVRHEAIIALAGKQLSPTAKTVDVSDVEAKEYLMGRDIPLATADKAQGEVIVCYGGAPLGMAKHLGNKLKNNLPRDLVKDKVLLLPEQTKSL
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_CHRVO
Sequence: MINEIKKSAEQKMQKTLEAFKNDLAKVRTGRAHTGILDHVMVDYYGSDVPVNQVANVTLIDARTIGVQPWEKPMLAKIEKAIRDSDLGLNPASMGEIIRVPMPMLTEERRKDLIKVVRGEAEGARVAVRNIRRDSNTEFKNLLKDKAITEDDERRGQDEIQKLTDKYTAEIDKMLATKEADLLAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIA_ECO27
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_EHRRW
Sequence: MNSDFICLGIITSPHGIKGHVKIKTFTENPQNFTSYGKLTDGITTYEINIIQVVSKNTIIAKINNITSRTNAELLRNKKLFIEKTKLPNLIENEFYHSDLVGLQVILEDNNIFGTIKKIYNFGSCDIIEILLYNSKKSTMLPFSKDIFTHINTKERYVILKLPEIIGSNSGI
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_CUPMC
Sequence: MARMVHCIKLNKEAEGLDFPPLPGDLGKKIWQNVSKEAWAGWLKHQTMLINENRLNMADPRARQYLIKQTEKYFFGDGADQAAGYVPPPAA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: CYSD_RHIME
Sequence: MPHTLPETELHNPQSTKPPLDPHLKALENEAIHIFREVAAEFERPVMLYSIGKDSSVLLHLARKAFYPGRIPFPLLHVDTGWKFREMIAFRDEMVAKYDLDLVAHTNPRGAAENVTPFTHGSALYTDIMKTEALRQALDAGQYDAAFGGARRDEEASRAKERIYSFRTPDHRWDPRNQRPELWNVYNGMIRKGESVRAFPLSNWTEVDIWRYIQAEDIPIVPLYFAKKRPVVERDGMLILAEDPRLELLPGEVKREEVIRFRTLGCFPLTGAIRSEADTLDDIIAELETATVSERQGRAIDRDQAGSMEKKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: TM100_RAT
Sequence: MTEEPTKENLGGPKSPTPVTMEKSPKSEVVVTTVPLVSEVQLTAATGGAELSCYRCIIPFAVVVFITGIVVTAVAYSFNSHGSVISILGLVLLSSGLFLLASSALCWKVRQRNKKVKRRESQTALVVNQRSLFA
What is the function of this protein?
Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10.  Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons.  Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.
What are the official names of this protein?
Transmembrane protein 100.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Perikaryon. Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Colocalized with HSPA5 in the endoplasmic reticulum (ER). Enriched in ER microsome. Colocalized with BMP4 in neural cell bodies and neural fibers of the enteric nervous system (By similarity).
Protein: HIS7_NEIMF
Sequence: MNLTKTQRQLHNFLTLAQEAGSLSKLAKLCGYRTPVALYKLKQRLEKQAEDPDARGIRPSLMAKLEKHTGKPKGWLDRKHRERTVPETAAESTGTAETQIAETASAAGCRSVTVNRNTCETQITVSINLDGSGKSRLDTGVPFLEHMIDQIARHGMIDIDISCKGDLHIDDHHTAEDIGITLGQAIRQALGDKKGIRRYGHSYVPLDEALSRVVIDLSGRPGLVYNIEFTRALIGRFDVDLFEEFFHGIVNHSMMTLHIDNLSGKNAHHQAETVFKAFGRALRMAVEHDPRMAGQTPSTKGTLTA
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSAPC_XENLA
Sequence: MEAPTLSELEGLRYSELQKLAKTVGLKANLKADKLLKDLKVHFYPESKDESPDYDGGSSLTDTDELNSSQEKDEPVSVSFVTHRRGRGRKPLKNHDTPKDEFLSVSVGAGTESLASETDNTQHQNCLESKKKEVSPPTIDNKHRKRSRSEDTSKQNNLETTEKRQKKASDITSAPSAGKIPRYVGRLSKPESKPSTPNFKKLHEAHFKKMESIDKYMERKQKRLDTVSSSIQEMKMLTKKSNLLKLVEKTPVSDIKKPVKSRLSLLSSLPPTTGASPSRTPTNQRRSGRFSAANKSILFDRSGFKPSVLSSSKMNVRFSEATKDNEHKRSLIKTPARKSSSFLAITPESEPRQMLPNVKKTPARKSLSVLAVTPESEPKQMLPSVKKNEPMTTPEKAKKTDLNTTIQPSTVILESTCPQNKEIAITPFKFTAQTTETPNTNKKGKFNLQASLSRPLGYQPHKGKLKPWGGSEENKCGSNNNVSVLKNNFKQPHLQTREDRRKQHEQDRKGKRDQTLGTRRGVPVQ
What is the function of this protein?
Microtubule-associated protein with the capacity to bundle and stabilize microtubules.  May associate with chromosomes and promote the organization of meiotic or mitotic spindle microtubules around them (By similarity).
What are the official names of this protein?
Nucleolar and spindle-associated protein 1-C, NuSAP C.
What is the protein family that this protein belongs to?
Belongs to the NUSAP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Associates with meiotic or mitotic spindle microtubules, particularly in the vicinity of chromosomes.
Protein: NIFH_CERS4
Sequence: MGKLRQIAFYGKGGIGKSTTSQNTLAALVEMGQKILIVGCDPKADSTRLILNTKLQDTVLHLAAEAGSVEDLELEDVVKIGYKGIKCTEAGGPEPGVGCAGRGVITAINFLEENGAYDDVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMALYAANNIAKGILKYANSGGVRLGGLICNERKTDRELELAEALAARLGCKMIHFVPRDNIVQHAELRRETVIQYAPESKQAQEYRELARKIHENSGKGVIPTPITMEELEEMLMDFGIMQSEEDRLAAIAAAEA
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: ARND_ENT38
Sequence: MRKVGLRIDVDTWRGTQQGVPHLLEILSLHGIQATFFVSVGPDNMGRHLWRLVKPQFLWKILRSKAASLYGWDILLAGTAWPGRQIGAGNADIISAAADHHEVGLHAWDHFAWQTWAGVWDNAHLEKHIRLGLDSLSQIIEQPVTCSAVAGWRADQRVVKAKESFGFRYNSDCRGTTPFRPVLADGSTGTVQIPVTLPTWDEVIGEGVSRENYNRFILDRIKQDTGTPVYTIHAEVEGIVMRKHFSELLEMAAQEGITFCPLSELLPDDLSTLPLGKVVRGAIPGREGWLGCQQLIDH
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: RSMA_LACDB
Sequence: MTNRIPIASPVRTAAIVNRYFVHAKKNLGQNFLVDLDAVQGIVRAAGIEPGDQVVEVGPGIGSLTEQLLLAGGKVAAYEVDQSLPEILANELPEKVDGQDLDQRFKLIMKDVLKADFATDLAGFFDLSKPVKVVANLPYYITTPIIFNLLESSLDFTSLTLMMQKEVAERLAAQPGSKAYGPLSIAVQTQMSVDLALEVGHASFMPQPKVDSAVVVLTPLEKPADVGDRKQFNRVVKLCFAQRRKTLANNLKTLLPDKEDREKLLADLDLDPRQRPEQLAISDFIRISQAIAEMNK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_ANAD2
Sequence: MKVRVVAVGRDRSGLYAPAVDEYAKRLGRYLRFELVEVPEARKLAGTAGAKGEEGATLLAKVGPRERVVVLDERGDELTSVAFAERVRRWMERGQDVALLIGGSDGLAPEVLARADERLAVSRFTLAHRLARLVLVEQLYRAMTILRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRE_NEIM0
Sequence: MEHYLSLFIKSVFIENMALSFFLGMCTFLAVSKKVSTAFGLGVAVIFVLGLSVPVNQLVYSLLKDGAIVEGVDLTFLKFITFIGVIAALVQILEMFLDKFVPALYNALGIYLPLITVNCAIFGAVSFMAQREYNFGESVVYGFGAGLGWMLAIVALAGITEKMKYSDAPKGLKGLGITFIAAGLMAMAFMSFSGIQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAK2_THEVB
Sequence: MAKVVGIDLGTTNSCVAVMEGGKPTVIANAEGFRTTPSVVAYTKNGDRLVGQIAKRQAVMNPENTFYSVKRFIGRRFDEVTHEATEVSYKVLNVNGNVKLDCPALGKQFAPEEISAQVLRKLKEDASKYLGEEVTQAVITVPAYFNDSQRQATKDAGKIAGLEVLRIINEPTAASLAYGLDKKANETILVFDLGGGTFDVSILEVGDGVFEVLATSGDTHLGGDDFDKKIVDYLAESFRAQEGIDLRKDRQALQRLTEAAEKAKIELSSVMQTEINLPFITATQDGPKHLDMTLTRAKFEELCSDLIDRCRVPVEQALKDAKLSKDQIDEVVLVGGSTRIPAIQELVKRLLGKDPNQSVNPDEVVAVGAAIQAGVLAGEVKDILLLDVTPLSLGVETLGGVMTKIIPRNTTIPTKKSEVFSTAVDGQTNVEIHVLQGEREMAADNKSLGTFRLDGIPPAPRGVPQIEVTFDIDANGILNVTARDKGTGKQQSISITGASTLPKEEVERMVREAEMNAAADKAKREKIETKNQAEQLCYQAEKQLNELGDKVSTSDKDRLTSLIANLRSEIGTEAEKKPIDAIDFGRVKSLMQDLQQALYSVGSSVYQSAQSSDGTGSSSSGGSGSGGDDEVIDAEFSETK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK2, HSP70-2, Heat shock 70 kDa protein 2, Heat shock protein 70-2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ENGB_PROA2
Sequence: MKIDSATFYKSCSELKGLPVSSLPEIVFVGRSNVGKSTLLNTLTGRKALAKTSSTPGKTQLINYFTINDRLYFVDLPGYGYAKVAKGQRYEWGRLLGGYISEREEISLVVLLIDSRHPDMESDQQMIEFLEYYQRPYGIVLTKYDKLKQKEKSRVRKALKSFSLKTKFIVNYSALSGEGKESLLEQLENYTG
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SYS_METC4
Sequence: MHDIRAIRENPEAFDRDLERRGLAPLSAELIALDDVRKGAVSAAQAAQERRNALSKEIGAAKKAKDEARATELMAEVARLKEEAPGLEAAQGEAAKALDERLAAIPNRPKDDVPPGADEHGNVEYRRFDSSRERLTQGRQHFELGEATGLMDFEAAAKLSGSRFVVLKGQLARLERALGQFMLDLHTGEHGYTEVVPPVLVREEAMFGTAQLPKFRDDQFAAGENFWLIPTAEVPLTNLVRESILAEDELPLRFTALTPCFRAEAGAAGRDTRGMLRQHQFNKVELVSITAPEKSAEEHERMLACAEAVLQKLDLTYRVMTLCTGDMGFASQKTYDIEVWVPGQQTYREISSCSVCGEFQARRMNARYRAKEGRGVGFVHTLNGSGVAVGRALIAVMENYQNPDGSVTIPSALQPYMGGLTRIEGPKN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_RICM5
Sequence: MSSNKINKKSIARIAAVQAIYQNILQNNDDMDDIMQNVLSFYQNNNSITDLPENLKISLSISHFKMLVKSVFENINKLDEIIDNHLTNDKDPAHMPILLRALLRVSICELLFCPTTPAKVVINEYTDIANDMLNEHEIGFVNSVLDKIAKEHTRLI
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NU4LM_MESMC
Sequence: MSITYMNMFMAFTISLLGLLMYRSHMMSSLLCLEGMMLSLFVMMTMAILNTHLTLASMIPIILLVFAACEAALGLSLLVMVSTTYGMDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RIMP_XANAC
Sequence: MSEKATEIANLLSPTVESLGLELLGVEYLPAPGGATLRLYIDVPLAEQPERVINVDDCERVSREVSAQLDVEDPISGNYTLEVSSPGVDRPLFTLEQFARHTGESAKIVLKLAQDGRRRFQGQILRIDAEAAAVVFAVDGKDVQIGYDNIDKARIVPDWVALGLAPQKPNKPGPKKPGHEKKKPSNESAAGKPRAE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_WOLSU
Sequence: MFEATTILAYKGENHSVIGGDGQVTFGNCVLKGNATKIRMLYNGKILSGFAGSTADAFTLFEMFERILENRKGDLVKSVIDFSKEWRKDKYLRRLEAMMIVMDRERLFILSGTGDVVEPEDGKIAAIGSGGNYALSAARALDKFADLPESELVRESLLIAGELCIYTNTNIKLLEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_LISMH
Sequence: MYYYLITLAVIALDQLTKWIVVQNMEIGQKIEVIPGFLYWTSYRNDGAAWSILEGHMWFFYLITVIVIGIIIYIMQKYAKGKRLFSISLAFILGGAIGNFIDRILHQEVVDFVQTVWGNYYFPIFNVADAALSVGVVLMLVYVFVDDRKTKGIK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CEMA_AGRST
Sequence: MKKKKALPSLLYLVFIVLLPWGVSFSFNKCLELWIKNWWNTRQSETLLTDIQEKRILERFIELEELSLLDEMIKEKLKTHVQKPPIGIHKQIIQLVKIDNEDHLHIILHFSTNIICLAILSGSFFLSKKELVIFNSWVQEFFYNLNDSIKAFFILLVTDFFVGFHSTRGWELVIRWVYNDLGWAPNELIFTIFVCSFPVILDTCLKFWVFFCLNRLSPSLVVIYHSISEA
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: TSAD_MYCBT
Sequence: MTTVLGIETSCDETGVGIARLDPDGTVTLLADEVASSVDEHVRFGGVVPEIASRAHLEALGPAMRRALAAAGLKQPDIVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYEHGPLPECVALLVSGGHTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPGGKALDDLARTGDRDAIVFPRGMSGPADDRYAFSFSGLKTAVARYVESHAADPGFRTADIAAGFQEAVADVLTMKAVRAATALGVSTLLIAGGVAANSRLRELATQRCGEAGRTLRIPSPRLCTDNGAMIAAFAAQLVAAGAPPSPLDVPSDPGLPVMQGQVR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_CITK8
Sequence: MMMENFKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSRLGEEGRLLAIDRDPQAIAEAQAINDPRFSIIHGPFSALADYVSERELIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTFGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLSVLAPGGRLSIISFHSLEDRIVKRFMREQSRGPQVPAGLPMTEEQLKKLGGRELRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRC_RAT
Sequence: MGSNKSKPKDASQRRRSLEPAENVHGAGGAFPASQTPSKPASADGHRGPNAAFVPPAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
What is the function of this protein?
Non-receptor protein tyrosine kinase which shows higher basal kinase activity than isoform 1, possibly due to weakened intramolecular interactions which enhance autophosphorylation of Tyr-419 and subsequent activation (PubMed:26026271).  The SH3 domain shows reduced affinity with the linker sequence between the SH2 and kinase domains which may account for the increased basal activity (PubMed:26026271).  Displays altered substrate specificity compared to isoform 1, showing weak affinity for synaptophysin and for peptide substrates containing class I or class II SH3 domain-binding motifs (PubMed:26026271).  Plays a role in neurite elongation (PubMed:28220894).
What are the official names of this protein?
Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Mitochondrion inner membrane. Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell junction, focal adhesion. Note=Localizes to focal adhesion sites following integrin engagement. Localization to focal adhesion sites requires myristoylation and the SH3 domain (By similarity). Colocalizes with PDLIM4 at the perinuclear region, but not at focal adhesions.