PharMolix/UniProtQA huggingface dataset:
Protein: KAD_METBU
Sequence: MNVVLFGPPGAGKGTQAKELDKHYQIPHISTGDILRANVRDGTKLGKEAKGYMDKGELVPDEVLIGVIKNRLAESDCKPGYLLDGYPRTTPQADALSSILVEIGMPLEVVLNIDVADEELVTRLCGRYVCTCGESYHMKFNPPKKENVCDACGADLYQRDDDKEDVIRQRLDSYKEKTQPLISYYGEKGLLVDIDGTGAIDRIFSDICKTLDQYK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLUC_ATRSP
Sequence: HSQGTFTNDYSKYLDTRRAQDFVQWLMSTKRSGGITXXXXXXXXHADGTYTSDVSSYLQDQAAKKFVTWLKQGQDRRE
What is the function of this protein?
Plays a key role in glucose metabolism and homeostasis.  Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.
What are the official names of this protein?
Pro-glucagon.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: PGA22_CANAL
Sequence: MKYSTLAWLVIASYTVFAQDGTSVTGYTTTIVIPGSPPAGAGTAHGDTENTGTVHTTEHLTGTEETHTTGATPETTTIVAPTTTHENTTTHETSVENTATVHHNTTTLHHNTTTIHPNATGTETHTETGTGTLTGTGTEGPALTTTTVAEAFSLAAGASLGYLVALLFL
What is the function of this protein?
Putative adhesin which may be involved in cell adhesion and virulence.
What are the official names of this protein?
Probable GPI-anchored adhesin-like protein PGA22, Predicted GPI-anchored protein 22.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: LDH_STRZP
Sequence: MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLHEKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELFEGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIGQPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYQ_HAMD5
Sequence: MNEASERPNHFIRHIIEEDLAQGKHSFIRTRFPPEPNGYLHIGHAKSICLNFGLAQDYQGECHLRFDDTNPEKEEQEYIESIKRDVQWLGFAWSGAVRYSSDYFESLYGYAIELIQKELAYVDELNAEQMREYRGTLTAPGKNSPFRDRTVEDNIELFKKMRAGGFAEGAACLRAKIDMASPFMIMRDPVLYRIKFAEHHQLGDQWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLENISIDCHPRQYEFSRLNLEHTLMSKRKLHLLVKEKKVTGWDDPRMPTLSGLKRRGYTPASIREFCHRIGVTKQDNQVEMSALEACIREDLNQNAPRALAVLDPVQLIIDNRSDEKEWLTVPNHPNNPGMGHRQMPFNRVLYIDRADFREEANKKYKRLVLGKEVRLRHAYVVKAKYVEKNAQGMITAIHCEYDPETLNKDPSDGRKIRGVIHWVSADDAVPAEIRLYHHLLTASHADTCLFLEAFNPESLFIRQGFVEPSLANTQEGKTYQFEREGYFCTDKDSSEKHLVFNRTVSLRGESALYDL
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLYA_SALPK
Sequence: MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEDKGLISRQTCASDRRAKRIKLTEKAEPLIAEMEEVIHKTRGEILAGISSEEIELLIKLVAKLEHNIMELHSHD
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.
What are the official names of this protein?
Transcriptional regulator SlyA.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: Y3883_PSEA8
Sequence: MAAKVEPFWKRKTLAQLDQDEWESLCDGCGLCCLQKLEDEDDGSVYYTRIACKLLDLQSCRCTNYAERIRFVPDCIQLTPAQADEFQWLPPTCGYRLVAEGKDLPLWHHLVCGDPERVHKERISQSGRMLSETQVAEDDWEDYLIFRAG
What are the official names of this protein?
UPF0260 protein PLES_38831.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: CRTQ_STAAC
Sequence: MKWLSRILTVIVTMSMACGALIFNRRHQLKAKTLNFNHKALTIIIPARNEEKRIGHLLHSIIQQQVPVDVIVMNDGSTDETARVARSYGATVVDVVDDTDGKWYGKSHACYQGVTHACTNRIAFVDADVTFLRKDAVETLINQYQLQGEKGLLSVQPYHITKRFYEGFSAIFNLMTVVGMNVFSTLDDGRTNQHAFGPVTLTNKEDYYATGGHKSANRHIIEGFALGSAYTSQSLPVTVYEGFPFVAFRMYQEGFQSLQEGWTKHLSTGAGGTKPKIMTAIVLWLFGSIASILGLCLSLKYRQMSVRKMVALYLSYTTQFIYLHRRVGQFSNLLMVCHPLLFMFFTKIFIQSWKQTHRYGVVEWKGRQYSISKEQ
What is the function of this protein?
Catalyzes the glycosylation of 4,4'-diaponeurosporenoate, i. e.  the esterification of glucose at the C1'' position with the carboxyl group of 4,4'-diaponeurosporenic acid, to form glycosyl-4,4'-diaponeurosporenoate.  This is a step in the biosynthesis of staphyloxanthin, an orange pigment present in most staphylococci strains (By similarity).
What are the official names of this protein?
4,4'-diaponeurosporenoate glycosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. CrtQ subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSMG3_BOVIN
Sequence: MEGKPLLTSKQKTAVVCGVPTQVVCTAFSSHILVVVTQLGKMGTLVSLEPSSVTSDVGKPVLTTKVLLGKDEPLVHVFAKNLVAFVSQEAGNRAVLLALATKDKSMEAVKALQEVIQACQVW
What is the function of this protein?
Chaperone protein which promotes assembly of the 20S proteasome.  May cooperate with PSMG1-PSMG2 heterodimers to orchestrate the correct assembly of proteasomes.
What are the official names of this protein?
Proteasome assembly chaperone 3.
What is the protein family that this protein belongs to?
Belongs to the PSMG3 family.
Protein: ALR2_CALS4
Sequence: MFDEIRPTRVEVNLDSIVHNFREIKRVVGDRVKVMGVVKANAYGHGAYHVAKALVENGVDYLAVATVEEALELRSYGITAPVLILGYTPLSQAGEAVEKDVTFTAFDLKYVKELGEIASRKGKKAKIHVKIDTGMGRIGYTDFDLAEREIEEMSKLEGIELEGIFSHFATSDEKDKDYAREQFERFADMLKRLEKRGVNITLKHIANSGAITDLNYAYLDMVRPGITLYGSYPSNDVNKILDLRPAMNFKTKIVYIKEVPENTSISYGRTFITKRPSKIATLPIGYADGLNRLLSNNHEVLVRGKYVPIVGRVCMDQTMIDVTEVEGVEVGDEVVIFGEQEGKRITADDIAKKLRTIPHEVYCGISRRVPRIYIYRGEVFDVKNYLKI
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase 2.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: ASSY_MYCS2
Sequence: MSERVILAYSGGLDTSVAISWIGKETGKEVVAVAIDLGQGGEDMEVVRQRALDCGAVEAVVVDARDEFAEEYCLPTIQSNALYMDRYPLVSAISRPLIVKHLVKAAREHGGGVVAHGCTGKGNDQVRFEVGFASLAPDLQVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDVYDYTEDPTVHWNTPDEVVIGFDKGVPVSIDGRPVSVLQAIEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRHTDQKWGELVYDGLWYSPLKRALESFVAHTQEHVSGEIRLVLHGGHISVNGRRSAESLYDFNLATYDEGDSFDQSAAKGFVHLHGLSSRISAKRDLGI
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1309_SHESW
Sequence: MKKQLLSALIGVSLLVPMAASAADYVIDTEGAHASITFKVNHLGYSYVVGRFNDFSGDFSYDAAKPTAMTVNVTVNTLSVDSNHAERDKHIRGEDFLNTGKFAKATFASTSVEDKGNGDLVINGNLTLNGVTKPLAIKAHAVGEGQDPWGGYRAGFTGTTTFAMKDFGIKMDLGPASSHVELDLVVEGVRK
What are the official names of this protein?
UPF0312 protein Sputw3181_1309.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: EIF1A_CHICK
Sequence: MSRATKRKHVTREVLEEHVVPAPQQRIVRVLGSPGNNLHEVETADGSRFLASMPPRFRHHVWIKRGDFLLVDPIEEGAKVKAEMALVLLRPHVRFLQRQGLWPTAFAASPDRTPQESDGDSELFVNTNRATIETDTEEEEEDGGDTESSEEEEEDREEPLEDRPEDRPEDCADVGSAAQRRSTIETGT
What is the function of this protein?
May play a role into cellular response to oxidative stress.  May decrease cell proliferation (By similarity).
What are the official names of this protein?
Probable RNA-binding protein EIF1AD, Eukaryotic translation initiation factor 1A domain-containing protein, Protein Obelix.
What is the protein family that this protein belongs to?
Belongs to the EIF1AD family.
Protein: SYFB_LEPIC
Sequence: MKLSLDWMNDFTPLKEVGLDAILKKIAISVCEIDDATEFRPELDFVKIVRIESLEKHPSADKLQIAQVFDGSSKSQIVTGVTNVKIGDLVPLAIPGAKLGDKEILESELRGVKSSGMLCSEKELFLSEEGNGVWILNGLDQAEVGKTIRSFLYYNDIIFEVDNKSITHRPDLWSHFGFARELASQLRLPIVFNPFESLWNFDLSVKLPKVLENQNAHSYYASSISGVSVFPSKRKFQSRLQKCGVRVINNVVDVSNYVMLEMGQPTHFFDKKFLENQGGISLEVSFAKKGESFALLDETSPALEEEVLLIRNQGKPVAIAGVMGGKESAVQNTTTEIVMESAVFMRERIRKSIRSTGIRSDSSVRYEKGLEATTTLPVIRRALNLLKENGCSELKASEPVGFLHIPHKEVRIHTDIHFINAKLGVTLSQGDITDILERLHFIVSWKGEHLEVLVPKFRHNYDVTIPEDLVEEIGRTKGYDTIQVSPLLAEVKTPIRNLNRELERKCKTFFAIALKYHEVFNYSFQSYKENEFSGDPKLSVKIKNEMPEEQSVLRNSLLPSLLKNTRTNQDRFSEIKIFEFGRVYFNLPEPENEKKIFAFAVSLDKKSSEPDLKLLEEDFLKIKKEVESFLESIQIYEYTWKIQQETIFHPGANLCLVARSGKDGLETIVGNLGYVHPAILDSFELKKRVIYGSFEFERIVELWNQNRKVSRFVTPSQFPEAEIDLSILVGEKENTNVFTDLVKLERIPELKEGWVYSQFMGGNVPEGKKSVSYRFRLVNYERTFTQERIKEISDQLVILAGKNGFVLR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REHY_HORVU
Sequence: MPGLTIGDTVPNLELDSTHGKIRIHDYVGNGYVILFSHPGDFTPVCTTELAAMANYAKEFEKRGVKLLGISCDDVQSHKEWTKDIEAYKPGSKVTYPIMADPDRSAIKQLNMVDPDEKDAQGQLPSRTLHIVGPDKVVKLSFLYPSCTGRNMDEVVRAVDSLLTAAKHKVATPANWKPGECVVIAPGVSDEEAKKMFPQGFETADLPSKKGYLRFTKV
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (By similarity).  Seems to contribute to the inhibition of germination during stress (By similarity).
What are the official names of this protein?
1-Cys peroxiredoxin PER1, B15C, Rehydrin homolog, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GBPR_AZOBR
Sequence: MTPHRFPANWFLKARLKLRHLQLFVALDEHRNLHRAAASLTMSQPAASKLLGDLEESLGVTLFERHGRGVEPNWYGGLMIRHARTILSGLQEAGEELNDLLAGHSGSVSIGTVMAPAVELVVPVITTLTRDHPDLKIAVAVETSDVLAERVRQGVMDFAIGRLPDHVDASCFDYQEISSEELCFVCRDGHPLLRLGRPLTAADLVDATWILQPLGSLLRSRVEALFRAEGVPPPRKVIESASPVISLAMVAENDSVTVFARALAQVFSPTGSCTIVPFHKRFSVEPYGIFWLKDRPLSPGARTALAALRAASDTKMRRALEMPQPSSSSDIEMCMDSANNRI
What is the function of this protein?
Does not seem to be required for sbpA expression.
What are the official names of this protein?
HTH-type transcriptional regulator GbpR, Galactose-binding protein regulator, GBP regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PROB1_RHIME
Sequence: MTKARKALENYRRVVIKIGSALLVDRRTGLKKSWLDALCADIAALRAKGVEVLVVSSGAIALGRTVLDLPAGALKLEESQAAAAVGQIVLARAWSESLSTHAIVAGQILLTLGDTEERRRYLNARATIGQLLKLGSVPIINENDTVATTEIRYGDNDRLAARVATMVGADLLVLLSDIDGLYTAPPHLDPNARFLETVAEITPEIEAMAGGAASELSRGGMRTKIDAGKIATTAGCAMIIASGKPDHPLAAIEAGARSSWFAPSGSPVTARKTWIAGQLLPAGSLSIDAGAETALRSGKSLLPAGVRQVTGSFSRGDTIAIIGASGREIARGLAGYDADEARQIAGKKSAEIAAILGYAGRTAMVHRDDLVMTAPSGARLVEESDEGKGKLHA
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase 1, Gamma-glutamyl kinase 1, GK 1.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCA1_CANGA
Sequence: MDSPTLEDRENSIEDCDDDDDNIYINEETEEGHEKVLVTHAPQERIVPPLNFCPVERYLYRSGQPSPVNFPFLLNLNLKTIVWLANEEPQDSLLEFCDTHKINLQFAAINPDAGEDDNPWDGLTEHSIINVLQTIVTKENYPLLVCCGMGRHRTGTVIGCLRRIMGWNLASVSEEYRRFTGSRGGRILVELLIEAFDTALVEIDKKNAPDWLLTSLE
What is the function of this protein?
Putative tyrosine-protein phosphatase required for protection against superoxide stress.
What are the official names of this protein?
Putative tyrosine-protein phosphatase OCA1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX38_CENMA
Sequence: ARDGYIVDEKGCKFACFIN
What is the function of this protein?
May block sodium channels (Nav) found (By similarity).  Reversibly modifies the firing of DRG neurons by causing membrane depolarization and increasing the number of action potentials (PubMed:25633390).  Shows antimicrobial activity against the Gram-negative bacteria K. pneumoniae (MIC=64 uM), and only a very weak activity against S. aureus (PubMed:25633390).  Does not show hemolytic activity (PubMed:25633390).
What are the official names of this protein?
Toxin Cm38.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUSB_PSET1
Sequence: MKPAARRKARILALQAIYSWQLSGNAIADIEQQMLIENDVTKIDVEYFKDLASGVAVNYKQLDEAVSPHLTRPFDELDMVERAILRLSSYELKFREDVPYKVAINESIELAKMFGAEDSHKFVNGVLDKAVKHLRK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: Y5025_MYCGI
Sequence: MARTPDDSWDLASSVGATATMVAAGRAVASADPDPLINDPYAEPLVRAVGLDFFTRMLDGELDLSVFPDSSPERAQAMIDGMAVRTRFFDDCCLAAASAGVRQVVILAAGLDARTYRLPWPDGTVVYELDQPDVIAFKTQTLRNLGAEPAATQRPVPVDLREDWPAALRAAGFDATRPTAWLAEGLLIYLPPEAQDALFDTVTALSAPGSTLATEYVPGIVDFDGAKARALSEPLREHGLDIDMPSLVYTGARTPVMDHLRGAGWQVSGTARAELFARFGRPLPQDADGTDPLGEIVYVSATLAADA
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mflv_5025.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: PPK1_ACIBY
Sequence: MNTAITATTPTEYSYNDRYINRELSILDFHLRVLEQAVDPLHPLLERMNFLLIFSRNLDEFFEIRVAGVMEQFALGNESRSPDGLTPRQVLQKISETAHTAIERQYRILNEEILPKLREEDICFLRRGELTPAQSAWVKKYFQEQVAPVLTPISLDPAHPFPRLVNKSLNFIVTLEGKDAFGRQIDLAVVPAPRSLPRVVRLPDELTGGKEHHVMLSAIIHEHVSDLFPGMTATGCYQFRVTRNADLALNEDVEDLAKALKGELSSRRFGRAVRLEVTQNCPQHIYEYLLEEFDLNEEQLYKVDGPVNLARLVSNFKRPHLRYDSHTPVVPKVFKKTESIFSAMQKQDILLHHPFESFAPVIQLLREAARDPQVLAIKQTLYRSGADSEIVQVLAEAARNGKEVTAVIELRARFDEESNIEVANVLQEAGAVVVYGIVGYKTHAKMIMVVRRENNKLVRYVHLGTGNYHAMNARIYTDYGLMTTDKDLCEDVHRIFQELTGMGKMAKLKKLLHAPFTLHAQLINFIDEEIANAKAGRKAQIIVKVNALTEVQLINKLYEASQAGVQVDLIIRSICCLRPGLPNLSENIRVRSIVGRFLEHTRVYYFSNNGDARIYCSSADWMDRNLFNRVEACFPIEDPALKKRIYQQGLLNYLQDNQQAWLLQGDGTWIRAKPAEGEKLHNAQRELLETFK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: CALX_MOUSE
Sequence: MEGKWLLCLLLVLGTAAVEAHDGHDDDAIDIEDDLDDVIEEVEDSKSKSDASTPPSPKVTYKAPVPTGEVYFADSFDRGSLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTAELSLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIADPDAVKPDDWDEDAPSKIPDEEATKPEGWLDDEPEYIPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIISGDRRVVDDWANDGWGLKKAADGAAEPGVVLQMLEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQSNAMEYKKTDAPQPDVKDEEGKEEEKNKRDEEEEEEKLEEKQKSDAEEDGVTGSQDEEDSKPKAEEDEILNRSPRNRKPRRE
What is the function of this protein?
Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum.  It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits.  It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.  Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation.  Additionally it may play a role in receptor-mediated endocytosis at the synapse.
What are the official names of this protein?
Calnexin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Melanosome. Note=The palmitoylated form preferentially localizes to the perinuclear rough ER (By similarity). When bound to CD3 epsilon chains, calnexin's ER retention signal can be masked, permitting it to escape ER retention.
Protein: PEBA_SYNSC
Sequence: MFDPFLEELLSGIKARGAVPVEVPHGLEHNQSSKRSSTIKSWLWDVPGFRRWRVTRLDAGDSLQVLNSVAYPDYTYDHPLMGVDLLWFGAKQKLVAVLDFQPLVQDKDYLERYFDGLKSLNAQFPDLNGEETMRSFDPNQYFSSWLLFCRGGAEQATSSLPTAFSAFLKTYWDLHDKAVKIPSSINPIEVAQLQKNYDIYSAERDPAHGLFTSHFGSEWSDRFLHEFLFPASQPK
What is the function of this protein?
Catalyzes the two-electron reduction of biliverdin IX-alpha at the C15 methine bridge.
What are the official names of this protein?
15,16-dihydrobiliverdin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: GLSK_MOUSE
Sequence: MMRLRGSAMLRELLLRPPAAVGAVLRRAQPLGTLCRRPRGGSRPTAGLVAAARLHPWWGGGGRAKGPGAGGLSSSPSEILQELGKGGTPPQQQQQQQQQPGASPPAAPGPKDSPGETDAFGNSEGKEMVAAGDNKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDDGKGNQTVHKNLDGLL
What is the function of this protein?
Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine.  Plays a role in maintaining acid-base homeostasis.  Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain.
What are the official names of this protein?
Glutaminase kidney isoform, mitochondrial, GLS.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. Cytoplasm, cytosol. Note=The 74-kDa cytosolic precursor is translocated into the mitochondria and processed via a 72-kDa intermediate to yield the mature 68- and 65-kDa subunits. SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion. SUBCELLULAR LOCATION: [Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix. Note=Produced by the proteolytic processing of the 74-kDa cytosolic precursor. SUBCELLULAR LOCATION: [Glutaminase kidney isoform, mitochondrial 65 kDa chain]: Mitochondrion matrix. Note=Produced by the proteolytic processing of the 74-kDa cytosolic precursor.
Protein: RL15_HALLT
Sequence: MTNKKRRQRGSRTHGGGTHKNRRGAGHRGGRGAAGRAKHEFHNYGPLGKYGFKRPESAQTEVLEVTVQKLDEDAALYAADDLAEEDGDAYVIDARDVVEDGYEADVVKVLGGGQVRRELRVTADAFTAGAVELIEEAGGEATLSERAEEAADESENTSDDEDDEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: FICD_DROWI
Sequence: MPWEFLKKCDRQKAEVRGEKEEQEPVPGNPHFQVQFHVTSCRFAFLAFLAGSFLAFSLHALISSNLFWRLRQLHHLPTAHYLQTRDEFAVYSVDELNAFKEFYDKSTADSVGATYTEAEETNIKEALSSLRLAQDMYMAGKDDKAARLFEHALALAPRHPEVLLRYGEFLEHNQRNIVLADQYYFQALTINPSHSEALANRQRTADVVQTLDERRLASLDAKRAALSAIHEANSALRRAKKEAYFQHIYHSVGIEGNTMTLAQTRSILETRMAVDGKSIDEHNEILGMDLAMKYINASLVQKLEITIKDILELHRRVLGHVDPIEGGEFRRNQVYVGGHVPPGPGDLAVLMQRFEDWLNSEYSSSLHPVNYAALAHYKLVHIHPFIDGNGRTSRLLMNTLLMRAGYPPVIIPKQQRSKYYHFLKLANEGDIRPFVRFIADCTEKTLDLYLWATSDLPQQIPMLIQTETEAGEQLVKLQSPQMASIPESFYESGSGALP
What is the function of this protein?
Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context (By similarity).  The side chain of Glu-255 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place (By similarity).  Acts as a key regulator of the unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of Hsc70-3/BiP.  In unstressed cells, acts as an adenylyltransferase by mediating AMPylation of Hsc70-3/BiP at 'Thr-518', thereby inactivating it.  In response to endoplasmic reticulum stress, acts as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from Hsc70-3/BiP at 'Thr-518', leading to restore HSPA5/BiP activity (By similarity).
What are the official names of this protein?
Protein adenylyltransferase Fic, De-AMPylase Fic.
What is the protein family that this protein belongs to?
Belongs to the fic family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein.
Protein: LOLB_AGGAC
Sequence: MKKLKSYVLLVLAVLFLTACVTDQERPTNVKYIEKTDRTWQQHFTQLKQIQGYPALGQLGYISSKERFSTRFDWQYNNPRDYTLQLYSTISSETLQIQMHAQGMTISDNKGRQRSAADAKMLLREIIGMDFPLEQFAFWLKGQPEDNADYQVGENHLLATFSRTIDGKPWTADYLSYHVNRRPPMPENILLKTEGQTLKIRVDEWLF
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: GAL1_CANMA
Sequence: MSISTVDDLSFYSNVEPNQQRFTEVVKTFQTNFPGDDITFFARSPGRVNLIGDHIDYNFFPVLPMAIANDVIAAVNVNSTNEIIITNTDSKDFLKEVIALRNSQIDQEHHSWANYFKCALIVAKQYLEERGVTSLKGMKLTFNGNVPTGGGLSSSAAFCVASTLAIIRANGITDLTKQDLTRITVVSEHYVGVNTGGMDQCASVCGEPDKLLLI
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
Protein: CARA_STRR6
Sequence: MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITDQSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLKAKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVSTKTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLSNGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVREIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDAAPGPHDASYLFDEFIEMMEVFKQSN
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.