PharMolix/UniProtQA huggingface dataset:
Protein: DHG_PRIMG
Sequence: MYKDLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNIGPGAINTPINAEKFADPEQRADVESMIPMGYIGEPEEIAAVAAWLASSEASYVTGITLFADGGMTQYPSFQAGRG
What are the official names of this protein?
Glucose 1-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: DCD_CHLPN
Sequence: MSIKEDKWIREMALNADMIHPFVNGQVNVNEETGEKLISYGLSSYGYDLRLSREFKVFTNVYNSVVDPKCFTEDIFISITDDVCIVPPNSFALARSVEYFRIPRNVLTMCIGKSTYARCGIIVNVTPFEPEWEGHVTIEISNTTPLPAKIYANEGIAQVLFFESSTTCEVSYADRKGKYQKQQGITVPCV
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: UBR3_DANRE
Sequence: MMAASLLRRDKKSTAAHLKADLKRTDNSSGLRQLQELLDSVLNPERGSDPEALDWCKWLLAGGDGFDEFCRTVRSYDNATLCGLVWTANFVAYRCRTCGISPCMSLCAECFNNGDHTGHDFNMFRSQAGGACDCGDGNVMRESGFCNRHRLKTGENVPSVPRDLLLMSEMVLPRFIITIIQYLRDGYTEPESAADRDLQKVLQQLDPHISFLEELTKMGGAMRTVLTKILTDQQTFKELSMGQEDNVYAKKNYEKYLSALKSSGLVSVEEKGAAGGAGDGTSDAAAGAGALSLLGATATASLDDSSKEEDQDGLQGVGQRKRVKLSSSTKDPSIMDTLKHKCFLEELLFWTIKYEFPQKMVTFLLNMLPDQDYKITFTKTFVQHYAFIMKTLMKSHESDTMSNRIVHISVQLFSNEELARHVTEECQLLDIMVTVLLYMMESCLIKSELQDEENNRHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKRFLEDHSLLLLWMSFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLTHCKVKETQDYTKTVVRYCLETLQMWFDAIGFVDEPSLNQLTFHLPLHRYYAMFLSKGVKCQGLDLDSLLPDQEMLMKIMVHPLQIQASLSEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHQNAVLDSEQERPMLEGALTFLVILCSLRIHLGMSDDEILRAEMVSQLCMNDRTHSSLLDLIPENPNPKSGVVPGSCSFEEMLSGVADFKAPVFEPGGSMQQGMYTPKAEVWEKEFDPIMVILRTVYRRDVQSAMDRYSAFLKQSGVHTGNPWPPYKERTPLHPCYKGLVRLLHCKTLHIVIFTLLYKIWMDHQNMSEHVLCMVLYLIELGLDNQVQDDKVEEEPCIEEHCHDSWFPGTSLLSNLHHVINFVRVRVPETAPEVERKRERERERETPPSTSSESATFGQNLREAQVFSLVAERRRKFQEIINRSNHEASQAVRPKSSASRWLPPGTPPQLVTEILEIRESMLSLLVKLHQKLSAKQNSLSLSWLAEVDPAHHAHGDGLTAIERILAKASARSRHSKRCLQEICGKVCPPIPPKKISPGDKKSMDKEERRQRARERQQKLLAEFASRQKSFMETAMDVESPEADAVMDVSSEESLDSEVLYDCVICGQSGPSTEDRPTGLVVLLQASSVLGHRCRSDMPKRLPTTDEEHIYPEDTCGATHDVRLSLMQRYFKDSSCLQSVSIGWDGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGISVDKGEFTCPLCRQFANSVLPCRPGRGMETGAWHAPSTKSMSTLVKEVEDLQEQLGIFPVRASIKQRDPILIESNLSKEMESVIKDIKNTTQKKYMDYGKNPGSPDNDFLFMYSVARTNLELELVHRGGNLCSGGASAAAKRSCLNQLFHVLAMHMRLYSIDSAYNPWTRLTLSTQSRENEYCDEERPEVPMLFRDVPSLLIIFILTMPQPLRKEHFTCVVKVLYSLQFTQALAALSIRFSREERLAWSNTGAAKKNLPNSDKSWESLLGHMISELTKAKDVYDTNSEETSALSSSVWSPQSIEFRLQQFCLPFLRLSCLLQHHLYGDSLPGCLVEEEFSLLTRCLGLAASVQCSGSMSSAACLEWNISAFDLISQWCSEVVALSDTPSQQSASLLGQDPQWAAPRLLQLPDNYNTIFQYYHRKSCSSCGKTPKDPALCLVCGAFVCLKGHCCKQQGVCECVLHSQHCGAATGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYLCEERYRVLEQQWVAHTFDHINKRWGPHYNGL
What is the function of this protein?
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway (By similarity).  Recognizes and binds to proteins bearing specific N-terminal residues, leading to their ubiquitination and subsequent degradation (By similarity).  Positively regulates hedgehog/shh-signaling pathways that function in eye development, neuronal specification and somite development (PubMed:27195754).  Activation of shh up-regulates transcription of ubr3, which in turn promotes hedgehog/shh signaling possibly by controlling negative regulators such as Kif7 (PubMed:27195754).
What are the official names of this protein?
E3 ubiquitin-protein ligase ubr3, E3 ubiquitin-protein transferase ubr3.
What is the protein family that this protein belongs to?
Belongs to the UBR1 family.
Protein: PK2L1_MOUSE
Sequence: MNSMESPKNQELQTLGNRAWDNPAYSDPPSPNRTLRICTVSSVALPETQPKKPEVRCQEKTQRTLVSSCCLHICRSIRGLWGTTLTENTAENRELYVKTTLRELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDSGVSFQTISSMSDFWDFAQGPLLDSLYWTKWYNNQSLGRGSHSFIYYENLLLGAPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGPQNGTAWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTVKLIRYVNNWDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLRYLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQLQLSDFLKQSYNKTLLRLRLRKERVSDVQKVLKGGEPEIQFEDFTSTLRELGHEEHEITAAFTRFDQDGDHILDEEEQEQMRQGLEEERVTLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEGVVSQIDAVGSKLKMLERKGELAPSPGMGEPAVWENLYNPS
What is the function of this protein?
Pore-forming subunit of a heteromeric, non-selective cation channel that is permeable to Ca(2+) (PubMed:16891422, PubMed:15548533, PubMed:19464260, PubMed:20538909, PubMed:21185261, PubMed:22420714, PubMed:25820328, PubMed:28904867, PubMed:29567962).  Pore-forming subunit of a calcium-permeant ion channel formed by PKD1L2 and PKD1L1 in primary cilia, where it controls cilium calcium concentration, but does not affect cytoplasmic calcium concentration (PubMed:24336288, PubMed:24336289).  The channel formed by PKD1L2 and PKD1L1 in primary cilia regulates sonic hedgehog/SHH signaling and GLI2 transcription (PubMed:24336288).  Pore-forming subunit of a channel formed by PKD1L2 and PKD1L3 that contributes to sour taste perception in gustatory cells (PubMed:16891422, PubMed:16929298, PubMed:20406802, PubMed:21098668, PubMed:21625513).  The heteromeric channel formed by PKD1L2 and PKD1L3 is activated by low pH, but opens only when the extracellular pH rises again (PubMed:18535624, PubMed:19464260, PubMed:20538909, PubMed:20406802, PubMed:22420714, PubMed:28904867, PubMed:29567962).  May play a role in the perception of carbonation taste (PubMed:19833970).  May play a role in the sensory perception of water, via a mechanism that activates the channel in response to dilution of salivary bicarbonate and changes in salivary pH (PubMed:28553944).
What are the official names of this protein?
Polycystic kidney disease 2-like 1 protein, Polycystin-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the polycystin family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle. Note=Interaction with PKD1 or PKD1L3 is required for localization to the cell membrane.
Protein: MIC25_MOUSE
Sequence: MGSAESAEARRVSFEMDEEERVRVLQGIRLSESVVNRMKDCSQPSAGEQLVPGFGPSSSAPVPTVPLPAISVPTVPAPTTPVPTAPSSSVRGLPGGTCKGPLTDVKVPSAESGGGLQSSAVKEDLKKFQQEQLAVQDEMVRVAKKEKEAAEKHLKASLPKKKASLTHEQQQSARLARELEDREAELSRRDTFYKEQQGRIQEKNAELYKLSSQQFHEAASKAESTIKPRRVEPVCSGLQAQILRCYRDHLHEVLLCSDLVKAYQHCVSTARKG
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit Mic25, Coiled-coil-helix-coiled-coil-helix domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Lipid-anchor. Mitochondrion.
Protein: LBD40_ARATH
Sequence: MRMSCNGCRVLRKGCSENCSIRPCLQWIKSAESQANATVFLAKFYGRAGLMNLLNTGPDHLRPAIFRSLLYEACGRIVNPIYGSVGLLWSGNWHLCQAAVEAVMRGSPVTPIACDAAVTGQAPPFNNKLCDIRHVSSRDENVKRRSRGACKEERNVRSLSHESSLSHESPVSSEETTTEEPKTWIGLELTLGLEPLARGNHVVVPMKKRKLERCGTSEDEDTCKIELGLVCSE
What are the official names of this protein?
LOB domain-containing protein 40, ASYMMETRIC LEAVES 2-like protein 37, AS2-like protein 37.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
Protein: PTHP_BACSU
Sequence: MAQKTFKVTADSGIHARPATVLVQTASKYDADVNLEYNGKTVNLKSIMGVMSLGIAKGAEITISASGADENDALNALEETMKSEGLGE
What is the function of this protein?
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes.  Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources.  P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMI_KLEP7
Sequence: MTDSLFPRLVLAKGREKSLLRRHPWIFSGGVARMEGKARSGETIDIVDHQGKWLARGAYSPSSQIRARVWTFDRNEAIDSAFFERRLQQAQTWRAWLAERDGLDSYRLIAGESDGLPGVTIDRFGNFFVLQLLSAGAEYQRAAIISALQNLFPDCAIYDRSDVAVRKKEGLELAQGPVVGELPPALLPITEHGMKLLVDIQGGHKTGYYLDQRDSRLATRRYVADKRVLNCFSYTGGFAVSALMGGCRQVTSVDTSQEALDVARQNVEINGLDLSKAEFVRDDVFKLLRKYRDQGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNPGGVLLTFSCSGLMTTDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA2_ECO57
Sequence: MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIAICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARSEFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAIAVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY
What are the official names of this protein?
Glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: LTOR3_PONAB
Sequence: MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSKLGLSKNKSTICYYNTYQVVQFNRLPLVVSFIASSSANTGLIVSLEKELAPLFEELRRVVEVS
What is the function of this protein?
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids.  Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag.  Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.  Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2 (By similarity).
What are the official names of this protein?
Ragulator complex protein LAMTOR3, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR3 family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ALR_HELPH
Sequence: MLKRASFVEVNSASLRHNFSAVKSIVPKDAHIMAVVKANAYGAGAIKASEIFLQEGANYLGVAALDEALELRSHFPKTPILILGYSPNANASMLIDNDLSAMVFSLEQAEVFSQMALKSQKRLKVHLKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIEGIFTHLSNADAKIKTHAKNQMKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMKESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMDQCFVKLNDIQAKEGDEVILFGDKSARANDASEIAALLNTIAYETISTLSKRLERVYI
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: ALDOB_PONAB
Sequence: MAHRFPALTQEQKKELSEIAQSIVANGKGILAADESVGTMGNRLQRIKVENTEENRRQFREILFSVDSSINQSIGGVILFHETLYQKDSQGKLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANALARYASICQQNGLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAAYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFLSGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAANKEATQEAFMKRAVANHQAAKGQYVHTGSSGAASTQSLFTACYTY
What are the official names of this protein?
Fructose-bisphosphate aldolase B, Liver-type aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Protein: PCKG_MYCSJ
Sequence: MTSATIPGLDTAPTEHEGLLAWVREVAELTQPDRVVFTDGSEEECARLTEQLCEAGTFQKLNEEKKPNSYLALSDPSDVARVESRTYICSEREIDAGPTNNWMDPAEMRGIMTDLYRGSMRGRTMYVVPFCMGPLEAEDPKLGVEITDSEYVVVSMRTMTRMGQAALDKMGTDGFFVKALHSLGAPLEPGEKDVPWPCNDTKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYFIAAAFPSACGKTNLAMLQPTIPGWRAETVGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNWSSNPNAMKTIEAGNTVFTNVAKTDDGDVWWEGLEGEPDHLIDWKGNDYILRETETKAAHPNSRYCTPISQCPTLAPEWDDPQGVPISAILFGGRRKTTVPLITQARDWQHGVFIGATLGSEQTAAAEGKVGTVRRDPMAMLPFLGYNVGDYFQHWIDIGKNADESKMPAVFFVNWFRRGDDGRFLWPGFGENSRVLKWAIERIEHKADGRSTPIGIVPTAQDLDLEGLDVDPEDVDAALAVKPEEWRQELPLIEEWFEFVGEKLPTGIRDEFDALKHRLAEEA
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIA2_RHISP
Sequence: MLGAGGRHLAVGRAGRAGVGRRHPAARAARHHRQRQRHGVHLERGPGLGDDTGVGWHYIAPGKPQQNGFNESFNGRLRDELLNETLFRSLPPLAPCGGVATRLQRAASALEARVADAAGLCRSAHRTQRPACCVVDGCADRPLANPADHSSDQPRTLVMAG
What are the official names of this protein?
Insertion element ISR1 uncharacterized 17 kDa protein A2.
Protein: RNPA_MYCPU
Sequence: MKKIYHIRKNWEFQAIINSKRQVISKNLIFYYQRNNTFKIGVSIPKKFAGAVKRNFYKRQIMAILRDIQDLTNLEYKIVMIVRKNFMALDFLEKKKEIQKMLERFKNEKRK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CH601_GLOVI
Sequence: MAKQVVFDETARRALERGIDALANAVRVTLGPKGRNVVLEKKFGAPQIINDGVTIAKEIELENKLENTGAQLIKEVASKTNDVAGDGTTTACVLAQSLVKEGLKNVAAGSNPMNLKRGMEKTVRHLVAELEKVAKPVEGSQAIAQVAAVSAGNDDEIGEMIARAMETVGKEGVITVEESKSLTTELEVTEGMQFDRGYVSPYLVTDQERMEAVFDEPFLLITDKKISIITDLVPILEKVARAGRPLVIIAEDIEKEALATLVVNKLRGVLNVAAVKAPGFGDRRKAMLQDIAVLTDGEVISEDTGIKLENVTTDQLGKARKMTITKDNTTIVAEGNEAAVKARCAQIKQQIEETDSEYDREKLQERLAKLSGGVAVIKVGAATETELKDRKLRIEDAVNATKAAIAEGIVPGGGTALLHLAAGMGGFIDSLSGEEKIGARIIQKALEGPLRQIAENAGLEGSVIAEKVRNLEFNFGFNAMTNEYEDLVAAGIIDPVKVTRSALQNAASIAAMVLTTECIVVDKPEDDKTPAGAGGGGMPDFD
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_SHEB2
Sequence: MTTVSMRDMLQAGVHFGHQTRYWNPKMKPFIFGARNGVHIINLEHTVPMFNEALAFISNVASKKGKVLFVGTKRAAGEAIKESALSCDQFYVDHRWLGGMLTNWKTVRQSIKRLKELESQSVDGTFDKLTKKEALMRTRELEKLEKSLGGIKNMGGLPDVLFVIGADHEHIAIKEANNLGIPVVAVVDTNSAPDGVNYIVPGNDDAMRAIRLYTSSVAAAAKAGRGQDLAVQAEQDGFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RPOC_FRATW
Sequence: MNNGILHQNYNSKKFDIIKISLASPEVIRSWSHGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVVCERCGVEVEQAKVRRERMGHIDLVCPVVHIWYLKSLPSRIGLFLDMPLKNVEKVLYFESYIVTDPGMTPLEKKQLLTDEEYAEALENYGYEFEASMGAEAIRDLLADTDIESEIELLQAECEESKSTAKKEKAIKRLRLLETFQASGNKPEWMVMTVLPVLPPDLRPLVPIEGGRFATSDLNDLYRRVINRNNRLKKLLDLNAPDIIVRNEKRMLQEAVDALLDNGRRGRAVTGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPSLRLHECGLPKKMALELFKPFVYSKLRLGGHATTIKQAKRMVELEEAVVWDILETVINEHPVLLNRAPTLHRLGIQAFEPRLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTVESQLEARVLMMSTNNILSPASGQPIITPTQDIVLGLYYITREKEGARGEGKLFSSYEDVSRAYNSGTIDIHAKIKLRIDRQVFDTKGNTYNEKGVVNTTVGRALLLNILPEGLSFSLLNKVLVKKEISKIINQAFRVLGGKATVVLADKLMYAGFKYSTLSGVSVGVDDMTIPDNKEAKIEEAEKEIKQITEQYQSSLITENERYNNIINIWSKTSDEVGASMMDAISKDTVSINGEKKEIESFNSVYMMAKSGARGSYNQMRQLAGMRGLMAKPDGTMIETAITANFREGLSVLQYFTSTHGARKGLADTALKTANAGYLTRRLVDVAQDLVVIEEDCGTDDGLMFSAIVEDGEVKVPLVERALGRTLAADVVTEKGVVLLEAGTLLDENLVELLDDNGIDMIKVRSPITCKTRRGLCAKCYGRDLARERQVNVGESVGVIAAQSIGEPGTQLTMRTFHTGGAASLGITVSDIKVKTAGKIKFKNIRTVTNKEGQEIVISRAGEIIVSDTMGRVREQHKIPMGAVVPLASGKAVEIGDVIATWDPHAQPLITDVAGKVVLEDVIDGITSKHTYDDLTGQQTIEITSISQRTTSKNLKPVVKIVDEKGAELKSIPLAVGAVLNVADDSILEVGDIVAKIPLEGSKNKDITGGLPRVAELFEARRPKDAAILSPCDGMVRLGNRDTKEKQRIEIIDKNGHIVEEILLPKSRHLVVFDGEQVSRGDVLADGPTDPHDLLKYKGLEEFADYILIEAQSVYRMQGVVINDKHIETIVRQMLRKAVILDEGDSKFVKDESIELVRILEENDKLRKQGKKEVEYELVLMGITRSSLSTESFLSAASFQETTRVLTEASINSQIDNLRGLKENVLIGRLIPTGTGLAVRKESAKIEKMREELGVEDNMVFTDLSSFNPEEISFDSIQSQKEDKDINEDIEESLRNALESLDF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: DAPA_ALKEH
Sequence: MFHGSMVAMVTPMHPDGAVDEVSLARLVDYHVEHGTDAIVAVGTTGESATLDYDEHCHVMRKVVEAARGRIPVIGGTGANSTWEAIKLTRCAMEGGCDATLLVVPYYNKPTQDGLYRHFAAIADAVAIPQILYNVPGRTACDLLPDTVDRLADISNIVGIKEASTIERVHDLVERCSDRLDVFSGEDGLSREAVLAGAKGVISVTANVAPQQMHDMVAAALRGDEEEASRIDARLAALHSALFLESNPIPVKWAVSQMGLCGPSIRLPLTELSEQHHETVRQAMKLAGSL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36A_ARATH
Sequence: MVNIPKTKNTYCKNKECKKHTLHKVTQYKKGKDSLAAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKIVLRLQCQSCKHFSQRPIKRCKHFEIGGDKKGKGTSLF
What are the official names of this protein?
60S ribosomal protein L36a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.
Protein: CYT_SOLTU
Sequence: QTQNAHLEFVEVLNVKEQVVAGMMYYITLVATDDGYKKIYKTKIWVKEWENFKEVQEFKQIVYATK
What are the official names of this protein?
Cysteine proteinase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the cystatin family. Phytocystatin subfamily.
Protein: ENPP3_HUMAN
Sequence: MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI
What is the function of this protein?
Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (PubMed:29717535).  Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines.  Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic cells (By similarity).  Has also alkaline phosphodiesterase activity (PubMed:11342463).
What are the official names of this protein?
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3, E-NPP 3, NPP3, Phosphodiesterase I beta, PD-Ibeta, Phosphodiesterase I/nucleotide pyrophosphatase 3.
What is the protein family that this protein belongs to?
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein. Secreted. Note=Detected at the cell surface of basophils (PubMed:11342463). Detected at the apical plasma membrane of bile duct cells (PubMed:15072822). Located to the apical surface in intestinal and kidney epithelial cells. Secreted in serum, and in lumen of epithelial cells.
Protein: HBA_ANAPP
Sequence: MVLSAADKTNVKGVFSKIGGHAEEYGAETLERMFIAYPQTKTYFPHFDLSHGSAQIKAHGKKVAAALVEAVNHIDDIAGALSKLSDLHAQKLRVDPVNFKFLGHCFLVVVAIHHPAALTPEVHASLDKFMCAVGAVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PEPB_ECOL6
Sequence: MTEAMKITLSPQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGIRKVEWPDLDDAQRQELDNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGLHTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPELIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLASAAQENEPFWRLPLAEFHRNQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGWLHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_BACAA
Sequence: MSGFFITATDTEVGKTVVAGALAGVFRELGYNIGVYKALQSGHVASNPEGDAARLKVLSGVPIKEDEICPYSIEEPLAPRLAMKRAGRAVTLKDIIHHYNERLKEFNSLFVEGAGGLAVPYTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAKAHGLTVAGVILSGCKECEMERVQENKVMIEELSGVPVLGLLPFFEGEFTKEEVLESAKEYIMISKLEEFIRNESTVAHTSSN
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.