PharMolix/UniProtQA huggingface dataset:
Protein: RR8_STIHE
Sequence: MINDTISDMLTRIRNASIVRKKSVLIPYTKMNLKIAEILEKEGYILSFEINTNKAISITKKTSETNLRMLKIYLKYYKKYKTNFYKLNVIKNKKALSDFKNLIKLLKGKQGNKKTPCITNLKRISKPGLRIYVNHKELPRVLAGTGIYILSTSKGILTDREARFRGIGGEVLCSVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YIPF4_MOUSE
Sequence: MQPPGPPPAYAPANGDFTFVSSADAEDLSGSIAAPDVKLNLGVSGDFIKESTATTFLRQRGYGWLLEVEDEDPEDNKPLLEELDIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLAVVLFFSMISLYGQFRVVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPLIVIAPILLVVGSFEMVSTLIKLFGVFWAAYSAASLLVGEEFKTKKPLLIYPIFLLYIYFLSLYTGV
What is the function of this protein?
Involved in the maintenance of the Golgi structure.
What are the official names of this protein?
Protein YIPF4, YIP1 family member 4.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Protein: UREE_PSEMY
Sequence: MLVIHTRIAPQAAADAELELTFEARRKSRLRCFTTAGEEVGLFLERGQPALADGEFLQAKDGRIVRVRAKAEPLLHVTCASPFELMRAAYHLGNRHVALQLGDGWLRLPDDYVLKAMLEQLGATVEAVQAPYQPEQGAYGGGHHHSHHGDEEFNYGPRLHQFGVRK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRG_YERPY
Sequence: MHVTLVEINVKEDKVDQFIEVFRANHLGSIREAGNLRFDVLRDEHIPTRFYIYEAYTDEAAVAIHKTTPHYLQCVEQLAPLMTGPRKKTVFIGLMP
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
What are the official names of this protein?
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase, Autoinducer 2-degrading protein LsrG, AI-2-degrading protein LsrG, Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase, Phospho-AI-2 isomerase.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IR05_HCMVA
Sequence: MHTYTRACCMGGWYGRETRKRNSHKKVTKRAVEKRKQDSTRQKRRTGAWRPFHDCCCHLGSSVFSRPRAAKSPPFSPSVRAPTDQPADSPAGASGERRGSSDLGKLLNPCVFIW
What are the official names of this protein?
Uncharacterized protein IRL5, TRL5.
Protein: Y3503_DICDI
Sequence: MLFKSLQSITSVNSIQKNQISSVSVGSSQSNNNAALLDAAALVVIPGLLTVAAVAHI
What are the official names of this protein?
Uncharacterized protein DDB_G0283503.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PG104_VACCW
Sequence: MTDEQIYAFCDANKDDIRCKCIYPDKSIVRIGIDTRLPYYCWYEPCKRSDALLPASLKKNITKCNVSDCTISLGNVSITDSKLDVNNVCDSKRVATENIAVRYLNQEIRYPIIDIKWLPIGLLALAILILAFF
What is the function of this protein?
Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry.  Also plays a role in cell-cell fusion (syncytium formation).
What are the official names of this protein?
Protein OPG104, Protein F11, Protein J5.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG104 family.
Protein: SUCC_KLEP7
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVKSKEEIRAFAEHWLGKRLVTYQTDANGQPVNQILVEAATDIDKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKIAIDPLAGPMPYQGRELAFKLGLEGKQVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: ENOB_GADMO
Sequence: SITKIKAREIL
What is the function of this protein?
Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate.
What are the official names of this protein?
Beta-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 3, Muscle-specific enolase, MSE, Skeletal muscle enolase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P5F13_XENLA
Sequence: MDQPILYSQTSFPNFTYSPGVVQDGGNYQYLGNYNAPSYPQPFFHVPVIKSEFGAHEEETPGSCHAASFDWNLYPHFQISNQAASNSSGDPSPEGRTEEDGSVSEGRSSSSPSPNSPLVPSFAQYWHYPSWQQGNLTNQAHTLFDGGDEKPQQSRHSPTASLGSGASNTEDEEVPSAISSRAERGLCSPSPNNASCGPGTEEDGMTLEEMEEFAKELKQKRVALGYTQGDIGHALGILYGKMFSQTTICRFESLQLTFKNMCKLKPLLEQWLGEAENNDNLQEMIHKAQIEEQNRKRKMRTCFDTVLKGQLEGHFMCNQKPGARELTEIAKELSLEKDVVRVWFCNRRQKEKSKFRMSKGHEFVGGASPGSIQSEHISFTPIPANSQDYGLASLHPNRAPFYPPPFPRNELFPHMAPGISMGVLTG
What is the function of this protein?
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3').  Antagonizes the activity of nodal/activin signaling during gastrulation to suppress mesendoderm formation.  Acts maternally to inhibit vegt and beta-catenin-activated gene transcription, probably by forming a transcriptional repression complex on the promoters of target genes.  Binds to an octamer motif in interspersed RNA.
What are the official names of this protein?
POU domain, class 5, transcription factor 1.3, POU class V protein oct-60, XOct-60, XlPOU-60.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBC_AETCO
Sequence: MKTLYSLRRFYHVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGIGPGGEVIDTFPYFVSGVLHVISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGVGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICIFGGIWHILTKPFAWARRALVWSGEAYLSYSLAALSVCGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLAFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CX64_CONAA
Sequence: STGKRNAGKLTVTDDVEADRDTDPDDKDPSVHNSWRTVDCGGVPCEFGCCRIIDGKEKCREIDCD
What is the function of this protein?
Probable toxin that inhibits ion channels.
What are the official names of this protein?
Conotoxin Am6.4.
Protein: MURB_MYCSJ
Sequence: MTGQELAGAEVEADVALAPLTTLRVGPVARRLITATSTEQLVAALRAPVGRDALILAGGSNVVLADDMADLTVIRVANSEITVHDGIVRAEAGANWDDVVVTALAHGLGGLECLSGIPGSAGATPVQNVGAYGSEVADTIRRVRLFDRRTGRDDWVTPQDMAFGYRTSVLKHSDHAVVLEVEFALDVGGRSAPLRYGELARALDVEPGGRADPVAVRDAVLALRRGKGMVLDEPDRDTWSVGSFFTNPVVTTADHERLAAEVDGPVPSYPAPDGVKLAAGWLVEHAGFGKGYPGDDAPARLSTKHALAVTNRGHATTADVIALARTVRDGVRTTFGIELTPEPTLVGCTL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BL1S4_CAEEL
Sequence: MTGVDDISSNVHKLVGVTAGMNTAASTGPMNLVLDKCSVVLEELRTIQILTETHSEGLSEQLKMTEKNILEMENLFDQIDQLCLFVQKAKSDLDKLEKLYNVVDRQ
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in gut granule biogenesis.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 4, BLOC-1 subunit 4, Protein cappuccino homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S4 family.
Protein: ESR1_SHEEP
Sequence: PSGYAVREAGPPAYYRPNSDNRRQGGRERLASTSDKGSMAVESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCY
What is the function of this protein?
Nuclear hormone receptor.  The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling.  Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components.  Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner.  Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace RELA/p65 and associated coregulators from the promoter.  Recruited to the NF-kappa-B response element of the CCL2 and IL8 promoters and can displace CREBBP.  Present with NF-kappa-B components RELA/p65 and NFKB1/p50 on ERE sequences.  Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response elements; the function involves CREBBP.  Can activate the transcriptional activity of TFF1.  Also mediates membrane-initiated estrogen signaling involving various kinase cascades.  Essential for MTA1-mediated transcriptional regulation of BRCA1 and BCAS3 (By similarity).
What are the official names of this protein?
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Golgi apparatus. Cell membrane. Note=Colocalizes with ZDHHC7 and ZDHHC21 in the Golgi apparatus where most probably palmitoylation occurs. Associated with the plasma membrane when palmitoylated.
Protein: DNAK_HALHL
Sequence: MGKIIGIDLGTTNSCVAVMEGNKTRVIENAEGDRTTPSVVAFAEDGEVLTGAPAKRQSVTNPENTIHAVKRLIGRRFDEDVVQRDIKEMPYKIVKADNGDAWVEAQGKKMAPPEVSARTLQKMKSTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGKIAGLEVKRIINEPTAAALAYGLDKEGGDKKVAVYDLGGGTFDVSIIEIAEVDGEKQFEVLSTSGDTFLGGEDFDKRIIDYLIQEFKKDQGIDLAQDHLALQRLREAAEKAKVELSSSQQTEINLPYITADQSGPKHMAIKLTRAKLESLVEDLVERTIEPCKTALKDAGLAAGDIQDVILVGGQTRMPKVQEKVKEYFGQDPRKDVNPDEAVAVGAAIQAGVLGGDVKDVLLLDVTPLSLGIETLGGVMTKIIEKNTTIPTKGTQTFSTAEDNQTAVTVHVLQGEREMAKDNKSLGRFDLTDIPPSPRGVPQIEVAFDIDANGILNVSAKDKATGKETGIEIKASSGLTEDEIERMVKEAEENAEEDRRQRELVEARNQAENMIHSTRKSLSDLGEQVGDAEKQEIESAISELEQVKDGEDKDAIEQKTQELATKAGELAQKAYQQAGGGDEASADAGAGETASGEQKEDVVDADFEEVKDEDGNSRK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL17_EHRRW
Sequence: MRHRVAHRKFSRTSAHRISMLLNLSISLIKHERITTTLPKAKELRPYVEKLITIGKVYREKNLVYGKRLLISKLKNIDATDKLIDVLSVRYKSRNGGYTRIMKNGFRKGDCAPIAIIELVDRQIVSQS
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PAND_HELPJ
Sequence: MTFEMLYSKIHRATITDANLNYIGSITIDEDLAKLAKLREGMKVEIVDVNNGERFSTYVILGKKRGKICVNGAAARKVAIGDVVIILAYASMNEDEINTHKPSIVLVDEKNEILEKG
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OX2R_HUMAN
Sequence: MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKLSEQVVLTSISTLPAANGAGPLQNW
What is the function of this protein?
Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369).  Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).
What are the official names of this protein?
Orexin receptor type 2, Ox-2-R, Ox2-R, Ox2R, Hypocretin receptor type 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CELF4_HUMAN
Sequence: MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY
What is the function of this protein?
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing.  Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing.  Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition.  Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs.  Activates the splicing of MAPT/Tau exon 10.  Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
What are the official names of this protein?
CUGBP Elav-like family member 4, CELF-4, Bruno-like protein 4, CUG-BP- and ETR-3-like factor 4, RNA-binding protein BRUNOL-4.
What is the protein family that this protein belongs to?
Belongs to the CELF/BRUNOL family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RPOZ_STAA9
Sequence: MLNPPLNQLTSQIKSKYLIATTAAKRAREIDEQPETELLSEYHSFKPVGRALEEIADGKIRPVISSDYYGKE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: TDCC_ECOK1
Sequence: MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLO2_SALCH
Sequence: MNLNSIPAFQDNYIWVLTNDEGRCVIVDPGEAAPVLKAIAEHKWMPEAIFLTHHHHDHVGGVKELLQHFPQMTVYGPAETQDKGATHLVGDGDTIRVLGEKFTLFATPGHTLGHVCYFSHPYLFCGDTLFSGGCGRLFEGTPSQMYQSLMKINSLPDDTLICCAHEYTLANIKFALSILPHDSFINEYYRKVKELRVKKQMTLPVILKNERKINLFLRTEDIDLINEINKETILQQPEARFAWLRSKKDTF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: PYRF_LISMF
Sequence: MNKPIIALDFQTYEEVETFLAKFSGETLSVKVGMELFYSNGPIIVEKIKQQHHEIFLDLKLHDIPNTVKSAMIGLAKLGVDMVNVHAAGGKKMMEAAREGLEIGSSSGKRPKIIAVTQLTSTSETDMQTEQLIKTSLLESVMHYSNLSKQAGLDGVVCSALEAEDIKQQNGADFLRVTPGIRLASDAADDQIRVVTPEKARLIGSSNIVVGRSITRANDPVEAYNQVLKEWNA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: NDHH_TRIEI
Sequence: MSQIQTRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVIDCEPVIGYLHRGMEKIAENRTNTMFVPYVSRWDYAAGMFNEAVTVNAPEQLADIAVPKRASYIRVIMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGYRMVNNNYFRIGGVAADLPYGWVDKCEDFCDYFLPKVDEYERLITNNPIFRRRIMGLGVISREEAINWGLSGPMLRASGVKWDLRKVDHYECYDDFDWEVHWEKDGDCLARYLVRIREMRESVNIIRQAIKGLPGGPYENLEAKRMAEGPKSEWNDFDYQFLGKKIPPTFKIPKGEHYVRIESGKGEIGIYIIGDNNIFPWRFKIRAADFVNLQIFPHILQGAKVADLVAILGSIDIIMGSVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase subunit H, NDH-1 subunit H, NDH-H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRPF_STAA8
Sequence: MKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRDNE
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: LPXB_FRATO
Sequence: MRIGIVAGELSGDQLGGTLVEALKQKYPNAIIEGIGGPKMAAAGFKSLYPMDALSLIGFLEIISKGLRILSIRRKIINYFKQNKPDIFIGIDAPDFNLTVEKELRSAGIKTIHYVSPKIWVWREYRIKKIRKATDKILAILPFETEYYKNRHKFEAIYVGHPLAKNIPIHIDRAKYRDKLGLKGSSLPILSVLPGSRTTEVSRLLPLFLLALQKLVDAGYKFKAIMPLAKPSLKPLFAKYKEQIDSLGIEVFETNSHDVLKASDLSLLASGTATLEAMLCKLPMVVGYKLSWLSALIGRMLIGNHSYWAFPNILHKNEIIKELIQEDCTVDNLFSELKRLFDDKRRNDYIVEEFEKIHKEMVIDTESKIIQVLDTMIEKS
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RIMP_SALTO
Sequence: MSQRGRATRPTGPTGRPRRTGGQRSAGRVSRGGDLASRRARLHEVVEPVVGEAGYDLEELSISRAGRRHVVQVIVDADGGIDLDAVADVSRAVSAALDAAEEARGDIVAGEYQLEVSSPGVSRPLTLPRHWRRNAGRLVRVTVRGGPDAGDRQLTGRVVEADDEQVVLETDAGRAGWSYAELGPGRVQVEFTRPGETDGADGADEAGDFDDDDDVEGEER
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_SALAR
Sequence: MVSRRVQALLEQLRAQGIRDEQVLDALAAVPREKFIDEAFEHKAWENIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVHHVCSVERIKGLQWQARRRLKQLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMAQLDEGGILVLPVGDEQQFLKRVRRRGGEFIIDTVEAVRFVPLVRGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_ERWT9
Sequence: MTKKKSHKPGSATIAMNKRARHEYFIEEEFETGLSLQGWEVKSLRAGKANISDSYILLRDGEAFLFGSTFQPLSVASSHIVCDPTRSRKLLLKKRELDTLIGKANRDGYTIVALSMYWKNAWAKLKIGLAKGKKEHDKRDDIKDREWKLDKARIMKHANR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.