PharMolix/UniProtQA huggingface dataset:
Protein: NLGN2_MOUSE
Sequence: MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDSGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSTEAVECLRRKSSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRTPGPGTSGTRRPPPPATLPPESDIDLGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPTAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV
What is the function of this protein?
Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members.  Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells.  Mediates cell-cell interactions between Langerhans beta cells and modulates insulin secretion (By similarity).  Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors).  Functions by recruiting and clustering synaptic proteins.  Promotes clustering of postsynaptic GABRG2 and GPHN.  Promotes clustering of postsynaptic LHFPL4 (PubMed:29742426).  Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of signaling by excitatory and inhibitory synapses and information processing.  Required for normal signal amplitude from inhibitory synapses, but is not essential for normal signal frequency.  May promote the initial formation of synapses, but is not essential for this.  In vitro, triggers the de novo formation of presynaptic structures.
What are the official names of this protein?
Neuroligin-2.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane. Presynaptic cell membrane. Note=Detected at postsynaptic membranes in brain. Detected at dendritic spines in cultured neurons. Colocalizes with GPHN and ARHGEF9 at neuronal cell membranes (By similarity). Localized at presynaptic membranes in retina. Colocalizes with GABRG2 at inhibitory synapses in the retina.
Protein: ACCD_HERA2
Sequence: MKDFFRRAPLPFTSSRREQQIPDNVWAKCANCGELTYQKQFNDALKVCPKCSYHSRISSREWIEVLADADSFVEYDADLQGIDILGFVSPKDNYEAKLAATSERTGTNDVVMSGSASIEGLPFEIAACNFEFMGGSMGSVFGEKVARAVERAADRGVPVLTINASGGARMHEGIFALMQMAKVSVALTRLARVRQPHISLLVDPCYGGVSASYASVADIILAEPGANIGFAGRRVIEQTIRQKLPPNFQTAEFFLEHGMIDAVVPRSDMRATIGRLLRLYQRPTSSADHREHVVAGHQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_CERS5
Sequence: MNYLEFEKPLSEIEGKAEELRALARGNKEMDVEKEAAALDRKAEALLKDLYKDLTPWRKCQVARHPDRPHCKDYIEGLFTEYMPLAGDRNFADDHAIMGGLARFNDNPVVVIGQEKGHDTKTRIERNFGMARPEGYRKAIRLMDLAHRFRLPVVTLVDTPGAYPGKGAEERGQAEAIARATQKCLELGVPLVTVVIGEGGSGGAVALATANRIAMLEHSVYSVISPEGCASILWKDAEKMREAAEALRLTAQDLHKLGVIDRIIKEPLGGAQRGRRETVEAVGKAIEMMLKELVGRKPDWLIKDRRNKFLDMGSKGLAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_PYRIL
Sequence: MVRRFKPAVKYRRGSRTHGWGRVGQHRKSGSSGGKGMVGFHKHKWSLVMKYGESGTGWPFYGKHGFKQPPTIAIEWRPINVGSLSDIIKELKKEGKIAEEGGKYVIRLLELGYNKLLGGGHIDVPVIVYTPAASRTAVEKIEKAGGEVRIIPLIHK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: EFP_SYNS3
Sequence: MISSNDFRTGTTIELDGAVWRVVEFLHVKPGKGSAFVRTKLKAVQSGSVVEKTFRAGEMLQQALLEKSTLQHTYMEGEDFVFMDMSTYEETRLTAKQIGDSRKYLKEGMEVNVVTWNEKPLEVELPNSVVLEIAQTDPGVKGDTATGGTKPAILETGAQVMVPLFLSIGEKIKVDTRNDTYLGRENG
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB2_XYLFA
Sequence: MARGINKVILVGNLGNDPDIKYTQGGMTITTISLATTSVRKDKEGNTQERTEWHRVKFFGKLGEIAGEYLRKGSQCYIEGSIRYDKFTGQDGQERYVTEIVADEMQMLGGRSDGGGMGGGGERPQRQTSQRQDYAPRRQARQPSQSPQSSPPPMDDFADDDIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein 2, SSB 2.
Protein: ZSA5D_HUMAN
Sequence: MGQCRNWKWGLESFDFSINRRSSAPGQLESASQMRESWRHKAGRRMFSCPEESDPIQALRKLTELCHLWLRPDLHTKEQILDMLVMEQFMISMPQELQVLVKVNGVQSCKDLEDLLRNNRRPKKWSVVNFLGKEYLMQESDVEMAEIPASVRDDPRGVSSQRASSVNEMRPGEGQASQELQTLPRVPALSRRQEEDFLLPETTVMKSAPKALRPKPTLEKDLNVDREENTGLTSPEPQLPNGPSVVGAKEGKEPKKRASVENVDADTPSACVVEREASTHSGSRGDALNLRCPKRSKPDATSISQEGPQGGATPVGNSESPGKPEINSVYSPGPAGAVSHPNGQEAKELLPFACGVCNKRFTCNSKLAIHMRSHTGERPFQCNFCERCFTQLSDLRVHQRIHTGEKPYTCDICHKRFNRMFSLKCHKRSHTGEKPYKCKDCNQVFTYRKNLNEHKLIHSGEKPYKCPKCLRAFRRPETLKYHQKTHQETTAPRECEG
What are the official names of this protein?
Putative zinc finger and SCAN domain-containing protein 5D, Zinc finger and SCAN domain-containing protein 5D pseudogene.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPE_DEIRA
Sequence: MTHQPSPVIHHHFAPAKINLGLSVLGVRENGYHDLHSLMVPLTVGDELEIRPAGALTLRVEGADLPTDERNLVYRAARAYLDAAGAAGGADLVLHKRLPLASGLGGGSSDAASTLLALAELYPAPDHRPVDLPALALTLGADVPFFLLGGAALAEGVGERLTPVDDLPPVHLVLANAGAEVSAGDAYRWLDETGDFSGKLRLEAMRLALARGVEVPYFNSLQAGVLARVPSVLTTLEALADAGLHSVLMSGSGATCFGLAHDAAQAQAAAAALAQRCPGWWVTAAQVRLPLSDNSGGRT
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: TRHO_BURP0
Sequence: MTTVNLAAYRFVSLDSIEQWRPLVAARCNTLGLRGTILLAPEGINLFIAGPREATDAFVDYIRHDPLFEGKFADLPFKESLSDSQPFRRMLVRLKREIITMKKPAIKPELGRAPAVDARTLKAWLDQGHDDAGRPVVMLDTRNAFEVDVGTFDRALDYRIDKFSEFPAVIEANRADLEGKTIVSFCTGGIRCEKAAIHMKDVGIENVYQLEGGILKYFEEVGGAHYHGDCFVFDYRTALNPQLAPTADVTCFACRAVVPADAQQSPLYVPGKCCPACHPGDSGTPGRRAEPGAEPARAV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ATPD_STAHJ
Sequence: MANVANKYAKALFDVAIDKDRLDLMYDELSEVSEATKNYGEDLRAIDSNPNQPASERRKFVGIVFGDANYYLKNMLMILANNRHLVLINSIFKEFKSLYNEYHNEDSAIVESVYQLSDEELDRIKDLILKQTNLSQVHITTKINPELIGGFRVKVGTTVLDGSVKKDLEQIERKFRRVN
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AOFA_DICDI
Sequence: MSTLYDVVIVGGGLTGLNAAYQFKKAGLNVMVLKPKDRFGGRTESIKVEDYWFDLGGQWMGGTHKYLKELCDELGVKSFPQYDEGKHVLEINGKKVYYQGNISNLNKSYNLEGLFESISKIDELSAELNPDKPYAHSKSKEYDQLTVAQWVEKNVKGNDARSIIDWFCRVCVAAEPTEVSFLFFLHFIRTAGNYGLLADIHGGAQQDRLIGGSQQISEGLAKKIGEKHYTLNAPVRSIIQDANQCTIKTDNGSTYRSKYIVVAIPPTLAGRIHYSPSMPPRRDELTQRMPMGSVIKTITIYDEPFWRKEGYSAEAISDKGPIFICYDDSSHDDKKTAIVGFIAASAAKDWAEKSPEERKRAVLDCYARWWGPKALSPRIFLEKSWKEEEYSRGCYLGYTSPGTLYQCGEHLRAPVGRIHWAGTETASVWIGYMEGALESGFRVSKEIKDKLLNSKL
What are the official names of this protein?
Probable flavin-containing monoamine oxidase A.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: Y1370_PSET1
Sequence: MGRAYQNKKDSMAKTAGAKTKVYSKYGKEIYICAKNGGTDPDGNLSLRRLIERAKKDQVPAHVIDRAIDKAKGGGGEDYVATRYEGYGPGNCMIIVDCLTDNNKRTFADVRVCFTKANAKIGAQNSVSHLFDHLAIFVFDGDDDETVLEALMMADVDVTDVEVENGKVTVFAPHTEYNNTRTALEEMGVTEFDEDLISFVPQIAAPIEGEDVEVMERFLAMLEDCDDVQNVYHNAEF
What are the official names of this protein?
Probable transcriptional regulatory protein PSHAa1370.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_METM7
Sequence: MDVVFALGGSVLMPKEGASTENIQNYAQAFKKLKEMGHRVSVVVGGGNTARQYISVAREFTNESFCDEIGILATRMNSMLLISALGKDAVKQVPENFKDAELILNMDKILVMGGTHPAHTTDAVSATLAEFIDADLLVIATNVDGVYTKDPRCNEDAVKLDKINTKELLEITGSNSMSAGSSGVVDPLASKIIDRAKLKTIVIKGIPEEILASISGNHNGTTITP
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACES_CULPI
Sequence: MEIRGLITRLLGPCHLRHLILCSLGLYSILVQSVHCRHHDIGSSVAHQLGSKYSQSSSLSSSSQSSSSLAEEATLNKDSDAFFTPYIGHGDSVRIVDAELGTLEREHIHSTTTRRRGLTRRESSSDATDSDPLVITTDKGKIRGTTLEAPSGKKVDAWMGIPYAQPPLGPLRFRHPRPAERWTGVLNATKPPNSCVQIVDTVFGDFPGATMWNPNTPLSEDCLYINVVVPRPRPKNAAVMLWIFGGGFYSGTATLDVYDHRTLASEENVIVVSLQYRVASLGFLFLGTPEAPGNAGLFDQNLALRWVRDNIHRFGGDPSRVTLFGESAGAVSVSLHLLSALSRDLFQRAILQSGSPTAPWALVSREEATLRALRLAEAVNCPHDATKLSDAVECLRTKDPNELVDNEWGTLGICEFPFVPVVDGAFLDETPQRSLASGRFKKTDILTGSNTEEGYYFIIYYLTELLRKEEGVTVTREEFLQAVRELNPYVNGAARQAIVFEYTDWIEPDNPNSNRDALDKMVGDYHFTCNVNEFAQRYAEEGNNVFMYLYTHRSKGNPWPRWTGVMHGDEINYVFGEPLNSALGYQDDEKDFSRKIMRYWSNFAKTGNPNPSTPSVDLPEWPKHTAHGRHYLELGLNTTFVGRGPRLRQCAFWKKYLPQLVAATSNLQVTPAPSVPCESSSTSYRSTLLLIVTLLLVTRFKI
What is the function of this protein?
Rapidly hydrolyzes choline released into the synapse.
What are the official names of this protein?
Acetylcholinesterase, AChE.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Synapse. Secreted. Cell membrane; Peripheral membrane protein.
Protein: RL27_SALA4
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGEAVLAGSIIVRQRGTKFHAGTNVGCGRDHTLFAKADGKVKFEVKGPKNRKYISIVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: TOP3_BACAN
Sequence: MAKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHLVTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVATDAGREGELVARWIIDKVRINKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVARSEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIANREDEIKNFKAQTYYGIEAQTTNQLKLTWQDANGNSRSFNKEKIDGIVKGLDKHNATVLEIDKKQKKSFSPGLYDLTELQRDANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRPLAHKVLQKPIKANKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVLFPAFEYEQLTLRTKVGNETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPRIEKGDTLTVKLIMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVATRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGKLKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQDRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGNKADKRDVQKYMKQQKKEEEPLNNPFAEALKKLKFD
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: NCAP_CVHOC
Sequence: MSFTPGKQSSSRASSGNRSGNGILKWADQSDQVRNVQTRGRRAQPKQTATSQQPSGGNVVPYYSWFSGITQFQKGKEFEFVEGQGPPIAPGVPATEAKGYWYRHNRGSFKTADGNQRQLLPRWYFYYLGTGPHAKDQYGTDIDGVYWVASNQADVNTPADIVDRDPSSDEAIPTRFPPGTVLPQGYYIEGSGRSAPNSRSTSRTSSRASSAGSRSRANSGNRTPTSGVTPDMADQIASLVLAKLGKDATKPQQVTKHTAKEVRQKILNKPRQKRSPNKQCTVQQCFGKRGPNQNFGGGEMLKLGTSDPQFPILAELAPTAGAFFFGSRLELAKVQNLSGNPDEPQKDVYELRYNGAIRFDSTLSGFETIMKVLNENLNAYQQQDGMMNMSPKPQRQRGHKNGQGENDNISVAVPKSRVQQNKSRELTAEDISLLKKMDEPYTEDTSEI
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the betacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: PMP1_YEAST
Sequence: MTLPGGVILVFILVGLACIAIIATIIYRKWQARQRGLQRF
What are the official names of this protein?
Plasma membrane ATPase proteolipid 1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: ROP1L_DANRE
Sequence: MPLSETMYCAQQINIPPALPNMLKQFTKAAIRTQPRDVLQWAADYFSALSKGQDLPVKKRLELPVATQKTDTGLTPGLLKILHQQLTSKETVTKDELLPKWKALHLPVEQLDTILALGNFSENINWMQFFALACSALGGSITSALKHACEILTEDPEGGPAQIPFHMFRSLYTYLAHLDGEIPEEQIDSFLHSLEGQAQSQGGMVQPSNFTSLHTAEK
What is the function of this protein?
Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia.  Important for male fertility.  Involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.
What are the official names of this protein?
Ropporin-1-like protein.
What is the protein family that this protein belongs to?
Belongs to the ropporin family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cell projection, cilium.
Protein: HNS_SALTI
Sequence: MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEESAAAAEVEERTRKLQQYREMLIADGIDPNELLNSMAAAKSGTKAKRAARPAKYSYVDENGETKTWTGQGRTPAVIKKAMEEQGKQLEDFLIKE
What is the function of this protein?
A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction.  Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensing the chromosome.  As many horizontally transferred genes are AT-rich, it plays a central role in silencing foreign genes.  A subset of genes are repressed by H-NS in association with other proteins (By similarity).
What are the official names of this protein?
DNA-binding protein H-NS, Histone-like protein HLP-II, Protein B1, Protein H1.
What is the protein family that this protein belongs to?
Belongs to the histone-like protein H-NS family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HSCB_ALIF1
Sequence: MNHFELFGLPNQFELDGGLLSLQFRELQKRFHPDNFATSSERDRLLSIQKAAQINDAYQTLKNPVSRAEYILSEQGHDIRGEQTTMQDPMFLMQQMELREELESLPSSSDPESALFDFAENVTAMRKSQLVQLQELLKNEAWIEAAQSVRKLKFIEKLNQEVEQLEEKLLG
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: UBIA_YERPE
Sequence: MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMRAAGCVVNDYADRHIDGFVKRTASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIWLSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAAVSESLPLVCWLLLLANICWTVAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFYWSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLVLFLGILISYW
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOCC_ECOL6
Sequence: MRIWAVLASFLVFFYIPQSYAGVALGATRVIYPEGQKQVQLAVTNNDDKSSYLIQSWIENAEGKKDARFVITPPLFSMQGKKENTLRIIDATNGQMPEDRESLFWVNVKAIPAMDKAKTGENYLQFAIVSRIKLLYRPQGLVIPPEQAPGKLEFTRENGGLTLFNPTPYYLTVTDLKAGNKSLENTMVPPQGKVTVNIPGGYTGGDITYKTINDYGALTEQVKGVVK
What is the function of this protein?
Involved in the biogenesis of the F1C fimbriae.
What are the official names of this protein?
Chaperone protein FocC.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MICU1_BOVIN
Sequence: MFRLNSLSALAELAVGSRWYHGGSQPTQIRRRLMMVAFLGASAVTASTGLLWKRALAESPPSANNIKSELGDKGKSKEEGEDCNAEKKAAGVCLEPYPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEHGESEVFMTPQDFVRSITPNEKQPEHLGLDQYTIKRFDGKKIAQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRSTTGNTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQKQLKKHFKEGKGLTFQEVENFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLMRGLEKPKDMGFTRLMQAMWKCAQETAWDFALPKQ
What is the function of this protein?
Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains.  MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium.  MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake.  Acts as a gatekeeper of MCU at low concentration of calcium, preventing channel opening.  Enhances MCU opening at high calcium concentration, allowing a rapid response of mitochondria to calcium signals generated in the cytoplasm.  Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake.  Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.
What are the official names of this protein?
Calcium uptake protein 1, mitochondrial, Calcium-binding atopy-related autoantigen 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MICU1 family. MICU1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space. Note=The topology is subject to debate.
Protein: RUVA_SHESA
Sequence: MIGRLRGVLIEKQAPEVLIDVNGVGYELQMPLTSFYELPEVNQPTTVYTHFVVREDAQLLYGFITKQERSLFRLLIKANGVGPKLALTILSGMTASEFVGCVERDDIVTLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFVLQSNYSPAPTVNSAEEDAISALISLGYKPPQASKAVSAAYKEGMDSETLIKAALKSML
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RS21_AZOVD
Sequence: MPAVKVKENEPFDVALRRFKRSCEKAGVLAEVRSREFYEKPTAERKRKAAAAVKRHAKKVQREQRRRERLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: OAZ2_DANRE
Sequence: MVKSNLQRILNSHCFAREKEGKKQCESSIMEALSSSITDRMASPTVCCSSTTGPGPLWCSDAPHPPLKIPGGRGNGARDHPSTTQTLYSDRKLTVTEEPAGPGRPQILHFQSRPAAARLIQWEAVLRGDGLFVEIPCEPFPDGSKESFISLLEFAEEHLKVVSVFVCFYKNREDRVKLVRTFSFLGFEMVKPGHALVPARPDVLFMAYNFDRDSSDED
What is the function of this protein?
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels.  Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers.  Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity.
What are the official names of this protein?
Ornithine decarboxylase antizyme 2, ODC antizyme, long form, ODC-Az-L.
What is the protein family that this protein belongs to?
Belongs to the ODC antizyme family.
Protein: AMIF_HELPG
Sequence: MGSIGSMGKPIEGFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEEFLLDVPGKETELYAKACKEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQGKIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCICHDGMIPELAREAAYKGCNVYIRISGYSTQVNDQWILTNRSNAWHNLMYTVSVNLAGYDNVFYYFGEGQICNFDGTTLVQGHRNPWEIVTGEIYPKMADNARLSWGLENNIYNLGHRGYVAKPGGEHDAGLTYIKDLAAGKYKLPWEDHMKIKDGSIYGYPTTGGRFGK
What is the function of this protein?
Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.
What are the official names of this protein?
Formamidase, Formamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.