PharMolix/UniProtQA huggingface dataset:
Protein: NLTP3_LENCU
Sequence: MARSMNLACVALVMCMVVIAPMAEAAVSCGTVTGDLAPCIPYLTGGAGPTDSCCAGVKKLLAAAPTTADRQAACNCLKTAAGNINNLNPGNAAALPGKCNVNIPYKISTTTNCNTIKF
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 3, LTP3.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: NTPPA_SHIDS
Sequence: MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLACEKAQAGVAQTAQDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MERP_PSEFL
Sequence: MKKLLSALALAAVVAPVWAATQTVTLSVPGMTCSACPITVKKAISKVDGVSKVDVTFETREAVVTFDDAKTSVQKLTKATEDAGYPSSVKN
What is the function of this protein?
Involved in mercury resistance.  Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
What are the official names of this protein?
Mercuric transport protein periplasmic component, Mercury scavenger protein, Periplasmic mercury ion-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MerP family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TXDT1_ATRRO
Sequence: CAKKRNWCGKNEDCCCPMKCIYAWYNQQGSCQTTITGLFKKC
What is the function of this protein?
Inhibits tetrodotoxin-sensitive voltage-gated sodium channels (Nav) by binding to site 3.  It slows the inactivation, causes a prolongation of action potential duration resulting in repetitive firing in autonomic and motor nerve fibers.  Does not depolarize the resting potential.  Does not affect tetrodotoxin-resistant sodium channels.  This lethal neurotoxin is active on both insect and mammalian voltage-gated sodium channels.
What are the official names of this protein?
Delta-hexatoxin-Ar1a, Delta-HXTX-Ar1a, Delta-atracotoxin-Ar1, Delta-atracotoxin-Ar1a, Delta-ACTX-Ar1a, Robustoxin, RBX.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 06 (delta-actx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPA_MYCLB
Sequence: MTVAPEDCRLLRLEVRNAQTPIERKPPWIKTRARMGPEYTALKNLVRRVALHTVCEEAGCPNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAALDRDEPRRVAESVQTMGLRYTTVTGVARDDLPDGGAWLYATTVRAIKELNPSTGVELLIPDFNGQPARLAEVFDSRPQVLAHNVETVPRIFKRIRPAFTYQRSLDVLTAAREAGLVTKSNLILGLGETADEVRTALADLRKTGCDIVTITQYLRPSMRHHPVERWVRPEEFVEYTQYAEGLGFSGVLGGPLVRSSYRAGRLYEQAAGTRTVGTSVSR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETKMT_DANRE
Sequence: MYRRIIMCFRSRATLNSFQRGMCCSTRRYVSSTGSEDDIKNFIIDNTEIVNSQSLTPEISLRLFTPTCRFWTENPEFWPFPDPYWAIYWPGGQALARYLLNNPEVSAGRKVLDLGCGCGASAIAARLSGASCVVANDIDPIAAIATKMNCELNNLAPLPCVTDNMIGSETDGWDLILLGDMFYDEALADGLHQWLQTCTNTHGTQVLIGDPGRAQFEDHNIRRSLHRLAHFQLPDSVKEENYGLTSSAVWRYNCKPDH
What is the function of this protein?
Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria.  Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain.
What are the official names of this protein?
Electron transfer flavoprotein beta subunit lysine methyltransferase, ETFB lysine methyltransferase, ETFB-KMT, Protein N-lysine methyltransferase METTL20.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. ETFBKMT family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion matrix.
Protein: MURB_MYCS2
Sequence: MASSHVAGVEIAEAVPLAPLTTLRIGPVARRMLTCTSTEQLIGVLRALTADDEPLLILAGGSNVVLADDLTDLTVVRIANTEITVDGDRVRAEAGALWDDVVVTSLAHGLGGLECLSGIPGSAGATPVQNVGAYGAEVADTITRVRLLDRRTGEDRWATTEELRFGYRTSVLKHSDAVIVLEVEFGLDAAGRSAPVRYRELATALGVEPGERTDPLRVRDAVLRLRTGKGMVVDPDPDHPDHDTWSVGSFFTNPVVTHADFERVERIARDAGAGPVPNYPAPDGVKLAAGWLVERAGFGKGYPGEGARARLSTKHALALTNRGQATTADVMALAGTVRAGVLDVFGIELTPEPILLGCVLSVP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLE_GLAP5
Sequence: MKAENIQLGIAPIGWTNDDLPELGAENTFEQCVSEMALAGYTGCEVGNKYPRDVAVLKHKLDVRGIQICNAWFSTFFVDGKREETIQEFIKHRDFLHAMGAKVIGCSEQSRSIQGTTKAVFKEKPIFNDEDWQRLAEGYNELAKLAAEKGMKVSLHHHMGTGIQTPEEVDRYMSVVNDDVYLLFDSGHLYYSEGCQKAMLAVLEKYIHRIVHVHLKDVRDEVVAEVKAKDLSFLEGVKKGTFTVPGDGVIDFKPIFDILEKYDYKGWMVVEAEQDPALANPFEYALKGRKYIREVAGV
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: CBPA1_HUMAN
Sequence: MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY
What is the function of this protein?
Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro (PubMed:8806703).  Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond (By similarity).
What are the official names of this protein?
Carboxypeptidase A1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SFSA_SALCH
Sequence: MLFSPPLQRATLIQRYKRFLADVITPDGTTLTLHCPNTGAMTGCATPGDTVWYSTSENTKRKYPHTWELTETQFGAFICVNTLRANQLTKEAIQENRLPALAGYNILKSEVKYGAERSRIDFMLQADFRPDCYIEVKSVTLAEKENGYFPDAITERGQKHLRELMGVAAAGHRAVVVFAVLHSAITRFSPARHIDIKYAQLLSEAQNKGVEVLAYKAELSAQKMELNEPVPITL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RSXA_ECO27
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL20_AZOVI
Sequence: MARVKRGVIARRRHKKILKLAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRQRKRQFRALWIARINAGDRQNGLSYSRLIAGLKKATIEIDRKVLSDLAVNEKAAFAAIVEKAKAVLA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RL10_RUBXD
Sequence: MKREQKAQIIEELAGKLRENSVVLVDYQGMDVAQSTELRRRSREAGVDFVVAKNTLTLRAAEEAGLPSLTEFLVGPTALAFSRDPVAAAKLMAEYADEIETFRLKGGLLEGSRVLNEQEVEALSKLPGRDQLIAQVVGGMAAPISGLVSVLNNTIQGLVVALGQIAEQKQAQQA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: NADE_EXIS2
Sequence: MQQEIIQVTGVKPVIDAEEEIKQRVQFLKEYLVHTGAKGLVLGISGGQDSSLAGRLCQIAVEELRSETNRDYQFYAVRLPYGQQQDESDAQLALSFIRPDHALRVDIKPAVAASMASFEQATGDVLSDFSKGNTKARERMKVQYDIAAHYGCLVVGTDHAAEFVTGFYTKHGDGACDLTPLTGLNKRQGKQLLRQLQAPEGLIEKVPTADLEDNQPGLPDEQALGMTYNEIDDYLEGKTISAESQAKLEAQYKRVGHKHHMPVSPLDTWWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: RL3_ERWT9
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEIEANRVTQVKGLENDGYTAIQVTTGAKKASRVTKPAAGHFAKAGVEAGRGLWEFRTAEGAEFTVGQSINVDIFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQLGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RET5_BOVIN
Sequence: MPPNLTGYYRFVSQKNLEDYLQALNVNMALRKIALLLKPDKEIDQRGNHMTVKTLSTFRNYVLEFEVGVEFEEDLRTVDGRKCQTIVTWEEEQLVCVQKGEVPNRGWRLWLEEEMLYQEVTARDAVCQCVFRKVK
What is the function of this protein?
Intracellular transport of retinol.
What are the official names of this protein?
Retinol-binding protein 5, Cellular retinol-binding protein III, CRBP-III.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DX39B_DROME
Sequence: MADNDDLLDYEDEEQTETTAVENQEAPKKDVKGTYVSIHSSGFRDFLLKPEILRAIVDCGFEHPSEVQHECIPQAVLGMDILCQAKSGMGKTAVFVLATLQQLEPSDNNTCHVLVMCHTRELAFQISKEYERFSKYMPTVKVAVFFGGMAIQKDEETLKSGTPHIVVGTPGRILALIRNKKLNLKLLKHFVLDECDKMLEQLDMRRDVQEIFRSTPHGKQVMMFSATLSKDIRPVCKKFMQDPMEVYVDDEAKLTLHGLQQHYVNLKENEKNKKLFELLDVLEFNQVVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQEERLNRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNEVQDRFDVNISELPEEIDLSTYIEGR
What is the function of this protein?
Required for mRNA export out of the nucleus.  Probable RNA helicase that may regulate entry into mitosis by down-regulating the expression of other genes whose activity may be rate-limiting for entry into mitosis during embryogenesis.  Binds to salivary gland chromosomes and modifies position effect variegation.  Promotes an open chromatin structure that favors transcription during development by regulating the spread of heterochromatin.
What are the official names of this protein?
ATP-dependent RNA helicase WM6, DEAD box protein UAP56, Dmrnahel, HEL/UAP56.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Locates to nuclei of embryos and ovaries, but disappears in mitotic domains of embryos as chromosomes condense.
Protein: PTH_STAS1
Sequence: MKCIVGLGNIGKRFEQTRHNIGFEVIDFMLEQNRFSLDKQKFKGAYTIERLAGEKVMFIEPMTMMNLSGEAVAPLMKYYDIDIEDLIVLYDDLDLPQGEIRLRQKGSAGGHNGMKSIIQMLGTDQFKRIRIGVDRPSNGMAIVDYVLQKFSNQEMETMNKVIEHSARAIEAYIESNRFDRVMNEYNGEIK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_PSE14
Sequence: MKSVEEQLALIKRGADELLVEAELVEKLKRGQPLRIKAGFDPTAPDLHLGHTVLINKLRQFQDLGHQIIFLIGDFTGMIGDPSGKSATRPPLTREQVLDYAETYKSQVFKILDPAKTEVAFNSTWMDKLSPADFIRLSSQYTVARMLERDDFDKRYKSNQSIAIHEFLYPLVQGYDSVALKADVELGGTDQKFNLLMGRELQRAYGQEPQCILTMPLLEGLDGVKKMSKSLGNYVGIQEAPGIMYSKLVSIPDSLMWRYFELLSFRSMEEINGLKADCEAGANPRDIKIKLAEELVARFHGEEAAANAHRSAGNRMKEGELPDDLPEISVAAIEDMPISAVLNKAGLVKNAAVARDLLASGGVRIDGEVVDRGFVFKLGATHVCQAGKKAFGRVTLVSEESSK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_ARTS7
Sequence: MSVQPTPADHFTFGLWTVGWTGADPFGVATRKNLDPVEAVHKLAELGAYGITFHDNDLIPFDATEAEREKILGDFNQALKDTGLKVPMVTTNLFSHPVFKDGGFTSNDRSIRRFALAKVLHNIDLAAEMGAETFVMWGGREGSEYDGSKDLAAALDRMREGVDTAAGYIKDKGYNLRIALEPKPNEPRGDIFLPTVGHGLAFIEQLEHGDIVGLNPETGHEQMAGLNFTHGIAQALWAEKLFHIDLNGQRGIKYDQDLVFGHGDLTSAFFTVDLLENGFPNGGPKYTGPRHFDYKPSRTDGYDGVWDSAKANMSMYLLLKERALAFRADPEVQEAMKTSGVFELGETTLNAGESAADLMNDSASFAGFDAEAAAERNFAFIRLNQLAIEHLLGSR
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNDL_BACSU
Sequence: MKPAKVSLLRRLLHSLKHVDCNIAKRFPSTIKIVKLLMIFMVFTPISSIYAEDVYQNFEELKNNEDPSDYGVVTKETGSPVLVLAIHGGGIEGGTSEVARELSKEYSMYLFEGLKSAGNSVLHITSTHFDEPRALKMTGNHEYVISLHGYAEEDQQIEVGGTDRVRAADLVEKLQHAGFPAVLLNMDHPHAGVSPNNIANKSKTGLSIQIEMSTGFRKSLFGIFSLKSRAVTQNERFYEFTEVMFRFLKNSY
What are the official names of this protein?
UPF0714 protein YndL.
What is the protein family that this protein belongs to?
Belongs to the UPF0714 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL10A_NEUCR
Sequence: MSKISVAAVRQHVTDLLEYSNETKKRNFLETVELQIGLKNYDPQRDKRFSGTIRLPSIPRPNMSICILGDQHDIDRAKHGGVDAMSVDDLKKLNKNKKLIKKLARKYDAFVASEALIKQIPRLLGPGLSKAGKFPTPVSHSDDLTGKLNEVKSTIKFQLKKVLCMGVAVGNVGMTQEQLVGNIMLAINYLVSLLKKGWQNVGSLTIKATMSPPKRLY
What are the official names of this protein?
60S ribosomal protein L10a, Cytoplasmic ribosomal protein 74.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ATPA_OENGL
Sequence: MATIRADEISNIIRERIEQYNREVKIVNTGTVLQVGDGIARIYGLDEVMAGELVEFEEGTIGIALNLESKNVGVVLMGDGLLIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEISSSESRLIESPAPGIISRRSVYEPLQTGLIAIDAMIPIGRGQRELIIGDRQTGKTAVATDTILNQQGNNVICVYVAIGQKASSVAQVVNALQERGAMEYTIVVAEAADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDPSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSRLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFSSDLDKATQNQLARGQRLRELLKQSQAKPLTVAEQILTIYTGTNGYLDSFEIAQVRKFLDELRDYVKTRKPQFEEIISSTKIFTEEAQALLKDAIQEQKELFLVQEKV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: KLH15_HUMAN
Sequence: MAGDVEGFCSSIHDTSVSAGFRALYEEGLLLDVTLVIEDHQFQAHKALLATQSDYFRIMFTADMRERDQDKIHLKGLTATGFSHVLQFMYYGTIELSMNTVHEILQAAMYVQLIEVVKFCCSFLLAKICLENCAEIMRLLDDFGVNIEGVREKLDTFLLDNFVPLMSRPDFLSYLSFEKLMSYLDNDHLSRFPEIELYEAVQSWLRHDRRRWRHTDTIIQNIRFCLMTPTSVFEKVKTSEFYRYSRQLRYEVDQALNYFQNVHQQPLLDMKSSRIRSAKPQTTVFRGMIGHSMVNSKILLLKKPRVWWELEGPQVPLRPDCLAIVNNFVFLLGGEELGPDGEFHASSKVFRYDPRQNSWLQMADMSVPRSEFAVGVIGKFIYAVAGRTRDETFYSTERYDITNDKWEFVDPYPVNKYGHEGTVLNNKLFITGGITSSSTSKQVCVFDPSKEGTIEQRTRRTQVVTNCWENKSKMNYARCFHKMISYNGKLYVFGGVCVILRASFESQGCPSTEVYNPETDQWTILASMPIGRSGHGVTVLDKQIMVLGGLCYNGHYSDSILTFDPDENKWKEDEYPRMPCKLDGLQVCNLHFPDYVLDEVRRCN
What is the function of this protein?
Substrate-specific adapter for CUL3 E3 ubiquitin-protein ligase complex (PubMed:27561354, PubMed:14528312, PubMed:35219381).  Acts as an adapter for CUL3 to target the serine/threonine-protein phosphatase 2A (PP2A) subunit PPP2R5B for ubiquitination and subsequent proteasomal degradation, thus promoting exchange with other regulatory subunits (PubMed:23135275).  Acts as an adapter for CUL3 to target the DNA-end resection factor RBBP8/CtIP for ubiquitination and subsequent proteasomal degradation (PubMed:27561354, PubMed:35219381).  Through the regulation of RBBP8/CtIP protein turnover, plays a key role in DNA damage response, favoring DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR) (PubMed:27561354, PubMed:35219381).
What are the official names of this protein?
Kelch-like protein 15.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROQ_NITOC
Sequence: MANLLVIHGPNLNLLGTREPKYYGSITLEAINSNLTHQAAQAGHHLTCFQANAEHILIEQIHSAAHQDIAFIIINPAAFTHTSIALRDALAAVAIPFIEVHLSNVHRREAFRRHSYFSDIAEGVISGLGPTGYELALQAVFARLLPP
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RL24_ALISL
Sequence: MAAKIRRNDEVIVLVGKDKGKKGKVTKVLETGKVIVEGINLVKKHQKPVPALGQQGGIVEKEAAIDASNIAIFNDATGKADRIGFRFEEGKKVRFFKSNGETISN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: NU2C2_GOSBA
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAIAEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGNSNGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLAPCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PUR7_NITEU
Sequence: MATAALFETSITSLPLLHRGKVRDIYAVDENHLLIIQTDRVSAFDVILPTPIPEKGKILTKISRFWFDKLAHIIPNHLTDITPESVVSSREQDQVSDRAFIVRKLKPLPVEAIVRGYISGSGWKDYQRSGTICGIALPAGLREADKIPDGAIFTPSTKAEAGSHDENISYSVCEQLLGVSLAAAVSRHSIALYTAAADYALTRSIIIADTKFEFGLDEANQLYLIDEALTPDSSRFWPAESYRPGKTPPSYDKQFIRDWLEQINWNKTPPAPPIPEEVLVQTIEKYQAACRVLTQ
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: S13A2_MOUSE
Sequence: MATCWQALWAYRSYLIVLCLPIFLLPLPLIVQTKEAYCAYSIILMALLWCTEALPLAVTALFPIILFPLMGIMEASKVCLEYFKDTNILFVGGLMVAIAVEHWNLHKRIALGVLLIIGVRPALLLLGFMLVTAFLSMWISNTATTAMMLPIGYAVLEQLQGSQKDVEEGNSNPSFELQEASPQKEETKLDNGQAVSVSSEPRAQKTKEHHRFSQGLSLCICYSASIGGIATLTGTTPNLVLQGQVNSIFPENSNVVNFASWFGFAFPTMVILLLLAWLWLQVLFLGVNFRKNFGFGEGEEERKQAAFQVIKTQHRLLGPMSFAEKAVTFLFVLLVVLWFTREPGFFPGWGDTAFANKKGQSMVSDGTVAIFISLIMFIIPSKIPGLTEDPKKPGKLKAPPAILTWKTVNDKMPWNILILLGGGFALAKGSEESGLSKWLGDKLTPLQHVPPSATVLILSLLVAIFTECTSNVATTTLFLPILASMAQAICLHPLYVMLPCTLAASLAFMLPVATPPNAIVFSFGGLKVSDMARAGFLLNIIGVLTITLSINSWSIPIFKLDTFPTWAYSNTSQCLLNPPNSTVPGH
What is the function of this protein?
Low-affinity sodium-dicarboxylate cotransporter, that mediates the entry of citric acid cycle intermediates, such as succinate, citrate, fumarate and alpha-ketoglutarate (2-oxoglutarate) into the small intestine and renal proximal tubule (PubMed:10966927) (By similarity).  Can transport citrate in a Na(+)-dependent manner, recognizing the divalent form of citrate rather than the trivalent form which is normally found in blood (PubMed:10966927).  Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic (By similarity).  Has a critical role in renal dicarboxylate transport (PubMed:17410095).
What are the official names of this protein?
Solute carrier family 13 member 2, Na(+)/dicarboxylate cotransporter 1, NaDC-1, Renal sodium/dicarboxylate cotransporter.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.