PharMolix/UniProtQA huggingface dataset:
Protein: SYT_STAAN
Sequence: MEQINIQFPDGNKKAFDKGTTTEDIAQSISPGLRKKAVAGKFNGQLVDLTKPLETDGSIGIVTPGSEEALEVLRHSTAHLMAHAIKRLYGNVKFGVGPVIEGGFYYDFDIDQNISSDDFEQIEKTMKQIVNENMKIERKVVSRDEAKELFSNDEYKLELIDAIPEDENVTLYSQGDFTDLCRGVHVPSTAKIKEFKLLSTAGAYWRGDSNNKMLQRIYGTAFFDKKELKAHLQMLEERKERDHRKIGKELELFTNSQLVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPMQLDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSYRDPEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDLHYDYARQLQDELKSQGVRVSIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKKHR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_SYNPW
Sequence: MALRLDGKALAKELEQRLAQQVRSGCAKAGRPPGLAVLRVGDDPASAVYVANKEKACARVGVESFGAHLPASSQPETLLKTIQALNADERVDGILLQLPLPAGLDETPLLAAIDPDKDADGLHTLNLGRLLKGEPGPRSCTPAGVMAMLRSQGIDPSGKRAVVVGRSILVGQPMALMLQAANATVMVAHSRTRDLAALTRQADILVVAAGRPEMIGAEHVAPGAVVVDVGIHRRPEGGLCGDVNAAELEPLAAALSPVPGGVGPMTVTMLLVNTVLAWSRRHQLDHDLADLVP
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: COAD_SYNE7
Sequence: MNAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLPNAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTEYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFHPVVERDRLT
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIFK_PYRAR
Sequence: MECRERRLAADLIALSSVEGLPVSEAAKRLCMTRQGLYKLLKQLRAEGYVAEGSVVKLTPKGRDFLSGILRDLLRYFNIASIRLVGRVVSGLGEGAFYISLEGYKRAIEERLGFTPFPGTLNIKLDPQYMPYRRYLDGLPGVVIPGFSNGLRTYGAVKAFRARVNGVEGAVVMPERTHHPTDVIEVVAPVKLRDALGLRDGDVVEVEVLL
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.
Protein: CEA_COLES
Sequence: MAKLLLFLLPAILGLLVPRSAVALGTNYLLSGQTLDREGHLKNGDFDLVMQDDCNLVLYNGNWQSNTANKGRDCKLTLTDYGELVIKNGDGSTVWRSRAQSVKGNYAAVVHPDGRLVVFGPSVFKIDPWVPGLNSLRFRNIPFTNNLLFSGQVLYGDGRLTAKSHQLVMQGDCNLVLYGGKYGWQSNTHGNGEHCFLRLNHKGELIIKDDDFKTIWSSSSSSKHGDYVLILRDDGFAVIYGPAIWETSPQAKEKMIGMVTAGKL
What is the function of this protein?
Mannose-specific lectin (Ref. 1).  Shows agglutinating activity towards erythrocytes from rabbit (Ref. 1).  Has insecticidal activity against cotton aphids and other hemipteran insects (Ref. 1).
What are the official names of this protein?
Mannose-specific lectin CEA, Agglutinin CEA.
What are the subcellular locations of this protein?
Secreted.
Protein: AROA_ENDTX
Sequence: MEIKLKKTNYVSGVIEVPSDKSITHRAVMLSSLAEGNSIVRDYLPSDDCNRTIEAFRQMGVEIKIDNGSLYVKGAGLKLAKPQNGKYNIYAGNSGTTTRLLSGILAGQDFETVITGDDSLSKRPMRRVILPLSQMGANIKSNDGLLPLIIKGRNPLKELNYESDKSTAQVKSAILFAGLFADGATTYKEPVKSRDHSERMLKAFGVNIKVNGNFVTVYPAEKLIAQDITVPGDISSAAFFIAAALIVPDSNLTIRNVGVNPTRDGLIEVLKQMGADITLANMREISQEPVCDIVVKYSKLKAADIDASLVPRMVDEIPVFVLIATQADGITRISGAKELRVKESDRIESVTSQFKKLGAQIESLEDGFIINGNSKFNLAGTIVDSFDDHRIAMTLAIASLIAEGETIIRDSHCVDISFPGFYKVLNNICR
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB33_ARATH
Sequence: MNRAENLDSIPTDLILEIFSRMSTKSIGRCRCVSKLWKSMLGHPYFTELFLTRSSDHPRLLFGVKRERQWLFFSSPQPQDLYEKSSLVDFHMNFSDFHMNFSGDIRRNECTYVSGFIYFPRKRIKNYLCDFRVICNPITGQYAILQLITFHEKRSFLGFDPIDKQFKVLRMKYNDRGIVVHHILTLEPGKMRWRKIRCPLAHEPFWEEICANGVLYYLAEPTDGGSYVICCFDVRSEKFKFIDAKCFGDFSIQLINYKGKLGGISWKYDTVDGKRTVELYMWVLEDVEKQKWSKYVYPLPGNSYHYSVAGVTAKGDIVFVKTYTSKPFYVFYVNPEKKTFQRVEIHGNHEVFDTNNLVYAFVDHVEDLQFDVMKKTYAAKPISPPKQKPKPPSTETSSREDHQGWISISSRKYHQVRTIAHRQQGRRKFESINKFNALYLDDGDEDTVAHQQRDHHTFKSISKFKAQRLLDDDEFTGVKTSKCDTSHLQNRVTAVHELHIWSITVGKVSLASQVSIKPEADTDAILDKVIEYIKRHHVTIQVEKEQNP
What are the official names of this protein?
Putative F-box protein At1g33020.
Protein: SYDND_WOLTR
Sequence: MNYYKTHTCNELRKNDVEKEVTLSGWMYRKRDHGNLIFVDLRDFYGITQLVFNNDKDFFCKISDLKPESVITVTGIVKARTEDTINISISTGEIEVTVNNLQIESEVEFHHNEETAKEERSILASIADDQEYPENMRFKYRFLDLRREKVRNNIVLRSQIIAELRKFMIEQGFLEIQTPILTASSPEGARDYLVPSRLNPGKFYALPQAPQIFKQLLMISGFDKYFQIAPCFRDEDARADRSPGEFYQLDLEMSFVTQEDVFQVIESTLYKVFAKFSRKSVDKGFSRITYKEAMLKYGSDKPDLRNPLLISDVTEIFRDSEFNIFKSNIERGMVVRAIPAPKTAEEPRSFFDKKIEHTQKEFGAKGLGYITFNKDGTAKGPIAKFLDDNRLNHIREATNIKPGDSVFFASDKENEAATIAGKVRTLLGSELGLIDNNIFKFCWVVDFPYFVYDDKSKKIDFFHNPFSMPHGGLKDLEEKNPLDILAYQYDLVCNGIELSSGAIRNNKLDIMYKAFATAGYNKEEVNKKFGALVRAFRFGVPPHGGIAPGIDRIVMLLADAPNIREITCFPMNQQGEDVLMDAPSKVDNKHLRELSLKVVE
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_NEIM0
Sequence: MLLIPAIDLKEGRCVRLRQGLMEEATVFSDSPAETALHWFKQGARRLHLVDLNGAFAGVPQNLPAIKDILAAVAKDIPVQLGGGIRDLKTIGQYLDLGLNDVIIGTAAVKNPDFVREACKAFPGRIIVGLDAKDGMAAIDGWATVTGHHVIDLAKRFEDDGVNSIIYTDIGRDGMMSGVNIDATVKLAQAVRIPVIASGGLTGLDDIRALCAAEKHGVAGAITGRAIYEGSIDFAQAQQLADSLD
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E4RF2_ADE02
Sequence: MFERKMVSFSVVVPELTCLYLHEHDYDVLAFLREALPDFLSSTLHFISPPMQQAYIGATLVSIAPSMRVIISVGSFVMVPGGEVAALVRADLHDYVQLALRRDLRDRGIFVNVPLLNLIQVCEEPEFLQS
What are the official names of this protein?
Early 4 ORF2 protein, E4-ORF2.
Protein: CM3D_CORMM
Sequence: MECTTVKLSVALGEEVVQLSTLDQQAQRAYANLLLVFKLSQNADADHVFSSLKRGLGAALTEVPDFASLVVPVPGSKKNELQLRLGPDSGVPFKLVRQDALASHLEKHSSGGTYAELARDNFPLASVPTELLFNQLPASELACARGLPGLLAQASVVDGGLIMGLSWHHTVSDARGINTLLSSWARHTKMWAGQGTIGSPSAAPEPTRDRWRLTCGPRDVHVSHFSDYQINAAARTPLSPAAAHLLDRPDTTNATAGLSTWYFSKKALSSLRGELGRAAADGSDAVQFTSGEAVSALVWKHLSLARLLHQQLAHETSLFASRIDFRGRAKPAFADGYIGNINEPNARTRMRLAEVCAPSSPASLVALAAAVREAIGAMDEKTMREFIGLVEGSSSVTDVYWDYNTFPGPDLVVTDMSGMDTLRQEWGGDLGQPVCIRSGSREKGVAYFLPQDAQGGFEVQLQCTAEDLGRLKDDSLFTKYAEFRS
What is the function of this protein?
Acyltransferase; part of the gene cluster that mediates the biosynthesis of beauveriolides I and III, cyclodepsipeptides acting as inhibitors of the acyl-CoA:cholesterol acyltransferase (PubMed:31926180).  The HR-PKS cm3B initiates the biosynthesis of beauveriolides by iteratively catalyzing the formation of the linear polyketide chain (Probable).  The ATP-dependent acetyl-CoA ligase cm3D converts the polyketide carboxylic acid to a CoA thioester which id shuttled to the first T domain in the NRPS cm3A by the acetyltransferase cm3C (Probable).  Cm3A contains 13 domains and assembles the polyketide chain, L-phenylalanine, L-alanine, and D-leucine (or D-allo-isoleucine) to form beauveriolide I (or beauveriolide III).  The production of both beauveriolides I and III suggests the substrate adaptability of cm3B, using different amino acids as substrates (Probable).
What are the official names of this protein?
Acyltransferase cm3D, Beauveriolides biosynthesis cluster protein D, Cyclodepsipeptides cm3 biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: PKS3_DICDI
Sequence: MNVSAYLPTCLPTYLPTCLPTYLPTYLPTYLPICLSEENNGIGIIGIGFRLPGGGSGKSLGNPSELWKELVNGYDGIIETNERWSDNFNKLGEINNRYGGLLPMDEVKSFDPLFFGISPPEATAIDPQQRLLLKCTWEAIEDAMIDPINLRGSNTSVFIGNTTHEYRDLNRTIDSIQTNIFSSSSHSSSNRVSNIFDFHGPSITIDTACSSSSNAVVLGCKSIIEGNSKMSIVGGTSLIFDANTPKSFSYMNMLSKDGRCKSFDANADGYVKSECIGVLLLKDLNQAIIDGDRVYCVIKGTSSNVDGNGYSDKSNFYSPSAQSQAENIKMALSSGNINAKDVDYVEAHGTGTPVGDPIEVEGISSIFKDNHSKENPLLIGSFKSMIGHCEASSGIASLVKCCLMFKNRYFIPNLHFKTPNPLIKFNEWNLKVVVEPTPFPKKEITMAVNNFGVTGSNVCIILKDFNYNHNSSSDNNNTINLKQQQHQNNIEYLIPFSANSTKSLEQYQSLISNFNQETMEFNDFVKEQIMSKSNSLYQRSVILGSNWNDFKDNLISTNNNIKTIKTTSSNISIKSKNPIIIMVFCGQGSQYNTMALELYKNEPIFRKTMDMLDNKLSKYYGFSILEKLRSIPVDDMKSIHNPALAQPAICMVQISLFELYKHWGIKPTFIVGHSLGEVTAAYCSGMIDLETECYLIYHRSIAQSTTTGCGRMLSINISPEKFIEQFSSRYPDVEISCYNSPTSIVIGGKEDQLNKISEELKSKGEFTSMLGSLSSFHTSSQKAIKEYILSLDYKSKESEIPIFSTVTTNLFDYKTTPYSPKYTYENILKSVNFTQTIENLYKHIENNQLGTDIVFIELAPHPTLQFYLKQMIPKDSSYFGKGDSISIYSPLHKKKNDVKEIRQTISQLYCQNGYNINFKCQFENINRSIVPTHKLPLYQWDEKQFWKINSLYENYYLTGPPIDILGNSITDSPFVKSYQTFINIKRKPFQYLKGHVVKGKFYFPGCGYIDNLLKIYPSQDITISTLEFSTPFIFTDDSVNHCLQTNIYPTGKTEYKVLFHFKDQKKNEWIQSSFGNFQLFKHNGEKSLKIFNQKYNIKDLIEKRCNLTKLTKEDLYDHIKLKTGLTYSGMFQAVSMCYLGDNCSLSVVSLELPKHLPDQKSFFNSSILDCCLHGMIGLVDEHCQLVFDRIEGFNLYSSNIPSARDQHTNVYVYSSLNAKMGDSYFASIVVMLEDGTVLIEIDNAACTSLTPIQDSLKIEAPTNELYSTYLQSKDSLILPPQTFESLYQQEKGQNDILVGTIIKQSLVPFVNEKMVFRILDFSSGFADYNGTTFHSSNNVLEKFNQLLKEFPLCEIDIEYTFGSVPQSLTSSIKDKLSHINERVSILYRDYSINDPLLLEDNQLKPSQYDIVLINDLEKETNDIKATLYMIYNLMVPNGQLILINNDGNNLIEIKELLDQCNFKDTIISNDKKSIIQTRKPQLLSELSPNPNIDSYDQIIIYSNDDSEICNKFLKSLESTDDKILSIISTISKFNEFVEKQSITDKSVIYFIKTMEQLTLDNFKSITFEYIEINRKLLKLNSMCKHVLITSDSRKDNYLASSVIGAARYFDEFQQLQLFTLDFDKESIIEYTHNNNEKNLVSLIELLTDKKISIQKEYLIRNGKVYFERIKKEQNLRKKFKSESYQDLVENDLVAVLSPNLEYELKPMTKDLEPFEVQVEIKSFALNYKDYLTYIGSVPPEMVNHKTGDINDPEFGSDFSGVITRVSKNNCSEFKVGDQVYGTAYNTASSKSIIDSGSIYFKPNNLSHEQASTIPVVYSTSLHSIYNIGNLKNYESILIHSASGGVGLSSLNILKWKGHCSYIFLTVGSPEKEKYLRDTYGSLITGIYSTRDKSYVQKIKDKLKELGSDKTGVDLILNTLSSDYMDSNFNCLSKSGRIVDLSITHLNSNEYIDNKKFKFNYGYHNVELLFIAAPILKKLLKSISKAIENNELINNLPITQYSNVNIKNAFEYINQRKHIGKIVVNHDTDLVGNLIKEKINSTSNLDFTLLKSNYQININNLGKNIIVTGQSGIVFEIIKWIVKFAPLVENIIILSKSSMKWQLELLVNRNKHIKFHFKSVDVGDINSMGKAIDEVSNDIDNIDSIFHYAFHQITKNVEAINMDTLDISFGAKTIGAIILHDQSIKRGWKLKNFIIASSVTSSLGSESQCSYVCANNVLESFSQYRKSLGLPSICTSYGLIKSTGFVSRNENVSVMFENLGFNPLSINTILGSLDLQIQNQELSTNLIVSSFNFSNITKYNPQKNNFSKIDYQVSLEEKNKVNQLGHDGNQDNKNSVNQMFLEKVSEVLSIEISKINIDIKLSAYGADSLSIVQLKNWVDKELSGNIITIQQLQTNTISSSIKIITNSLDKKKEGKNKSSTVVNNTNEITTTTKTFEYWKNEAKLDETIIASSIKSDLIIDNKMDKVILLSGSTGFLGGYLLLNLVKMKNCSKIYCLTRSGHLSDQIDLMNKIIDNLKHHKLFEMFEQSELEKIFPVRGDLRKSKLGLSDKMYLEISNQVNLILSCGADINLNANYDEIKPTNVDSTKEFIKLSVSKGTNKPMIPIVNLSSFSIFFGQKLNDEIEFDEYQVGIPSLSNLNNLPGGYIQSKLICEHLLLEASSRGIPAMTIRLPSIFSNPHTGIGHSGDLLQLIIKSISVTKYFPIEPTSLFISPVTWVAQNIINLIFNEGCWSKTKINTLNIISLNGELQTTNEIFLMIKKNFNYKETTLINWKKMISESNDKTCIRLRTFHPLDFTPTKYHMSKEFKISKNTKSLLISFGSYDGWNITEQMVLNLLKQ
What is the function of this protein?
Probable polyketide synthase.
What are the official names of this protein?
Probable polyketide synthase 3, dipks3.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EZHIP_MOUSE
Sequence: MASSSSPERGLEALRDTDESEGEAPGPSGPRGRGGPSGAGSALRLRSLEAEMAAACVTSTAGEDLGTFSEPGSQHGDPEGGGGPDLELGHARPMMRSQRELGLTPKGGGKADQGGKGRKGGSGSPPHTKSSRKREQPNPNRSLMAQGAAGPPLPGARGSPAMPQPESSLSPRPDQSHHFDFPVGNLEAPGPTLRSSTSQGSGSTPVPEALRCAESSRAESDQSSPAGRELRQQASPRAPDDDDDGDGGPDPRGSGTPEGWVLRSGVVPFGRRSSASEVSPEEVRPEAQCTGWNLRPRPRSSASAVSPEARPKAQSAGRNLRPRPRSSASVVSPEARPKAQSAGRNLRPRPRSSASVVSPEARPEAQSAGRNLRPRATPRVPVAPSSTTRSSSDRGSSRAPRSRSRSRSCSTPRLGSDHQRSRKIKMRLDLQVDREPESEAEQEEQELESEPGPSSRPQASRSSSRFAVPGRSSLAAEDSPPRRPVRMRASSPSPPGRLYPLPKHYFEGVHSPSSSSSESSSVSSSHSPLNKAPDPGSSPPLSSLSGPNPFWLALIADLDNLDSSSPRVPGEEIEAAPHTREEEDKKCRG
What is the function of this protein?
Inhibits PRC2/EED-EZH1 and PRC2/EED-EZH2 complex function by inhibiting EZH1/EZH2 methyltransferase activity, thereby causing down-regulation of histone H3 trimethylation at 'Lys-27' (H3K27me3) (PubMed:31086175).  Probably inhibits methyltransferase activity by limiting the stimulatory effect of cofactors such as AEBP2 and JARID2 (By similarity).  Inhibits H3K27me3 deposition during spermatogenesis and oogenesis (PubMed:31451685).
What are the official names of this protein?
EZH inhibitory protein, K27M-like inhibitor of PRC2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HETR_TRIEI
Sequence: MMKTDTDLINSLSPSAMDQIMLYLAFSAMRTSGHRHGAFLDAAATAAKCAIYMTYIEQGQNLRMTGHLHHIEPKRVKVIVQEVEEALTKGKLLKMLGSQEPRYLIQFPYVWLEQYPWTPSRSRLPGNNLTTEEKRYIEGKLPSNMPDARLINSFQFMELIEFLHRRSQEDFPPERRMPLSEALAEHIKRRLIYSGTVTKIDSPWGMPFYALTRSSYSPEGQEERTYIMVEDTARYFRLMKDWAENNNTNKVMRILEEFDISPDRFEQAKEDLDEIIRHWADRYHESGGKQMVVQMVFGLKDD
What is the function of this protein?
Might be involved in temporal and/or spatial regulation of nitrogen fixation.  Dimerization is required for DNA-binding.  Has both a protease and a DNA-binding activity.
What are the official names of this protein?
DNA-binding transcriptional activator HetR.
What is the protein family that this protein belongs to?
Belongs to the peptidase S48 family.
Protein: GLK_HELPH
Sequence: MPKTETYPRLLADIGGTNARFGLEVAPRQIECIEVLRCEDFESLSDAVRFYLSKCKESLKLHPIYGSFAVATPIMGDFVQMTNNHWTFSIETTRQCLTLKKLLVINDFVAQAYAISAMQENDLAQIGGIKCEINAPKAILGPGTGLGVSTLIQNSDGSLKVLPGEGGHVSFAPFDDLEILVWQYARSKFNHVSAERFLSGSGLVLIYEALSKRKGLEKVAKLSKAELTPQIISERALNGDYPICRLTLDTFCSMLGTLAADVALTLGARGGVYLCGGIIPRFIDYFKTSPFRARFETKGRMGAFLASIPVHVVMKKTPGLDGAGIALENYLLHDKI
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_HAEDU
Sequence: MKQIPMTVRGAELLREELEFLKNVRRPQIIDAIAEAREHGDLKENAEYHAAREQQGFCEGRIQEIEGKLGNAQVIDVAKMTNNGKVIFGATVGLVNIDTDEEVTYRIVGDDEANIKEGLISVNSPIARGLVGKSVDDSVSIITPGGKVEFDIISVEYQ
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides (By similarity).
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ATPA_MESHJ
Sequence: MNKDINIAAIIKNEIENFEGKIQNHDIGKVIIVGDGVALVSGIEKVKFGELVEFENNVLGIALNLEQDLIGVVIMASENSVFQGSIVRRTKSVISITVGDQLLGRVVNALGIPIDGKAELDNSLKSAIFTNAPSIMDRKSVDRGLKTGILAIDSLVPIGKGQRELIIGDRQTGKTTIAIDAILNQKGKDVYCVYVAIGQKNSSVAQIVSLLEKKGALEYTTVILAGASELSPLQYLAPYSGAAIAEYWMNKKKDVLIIYDDLSKHAIAYRTLSLLLRRPPGREAFPGDIFYQHSYLLERSAQLSNDKGGGSITALPIIETQAGDISAYIPTNVISITDGQIFLRDSLFNSGQKPAIDIGLSVSRVGSAAQTNLMKWASSSLKLNLAQYNELKAFAQFGSDLGPSSQLILDRGNKIYEILKQENQYPLTERQQIMLLILIRENLIDSLEQKSIPLFKSAFLKYCDSEPKFRDKIEKMDYNRVLEPNNLAGILKDITDFIEKFNLGNVF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CCZ1B_HUMAN
Sequence: MAAAAAGAGSGPWAAQEKQFPPALLSFFIYNPRFGPREGQEENKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPSKPAKSLHTQKNRQFFNEPEENFWMVMVVRNPIIEKQSKDGKPVIEYQEEELLDKVYSSVLRQCYSMYKLFNGTFLKAMEDGGVKLLKERLEKFFHRYLQTLHLQSCDLLDIFGGISFFPLDKMTYLKIQSFINRMEESLNIVKYTAFLYNDQLIWSGLEQDDMRILYKYLTTSLFPRHIEPELAGRDSPIRAEMPGNLQHYGRFLTGPLNLNDPDAKCRFPKIFVNTDDTYEELHLIVYKAMSAAVCFMIDASVHPTLDFCRRLDSIVGPQLTVLASDICEQFNINKRMSGSEKEPQFKFIYFNHMNLAEKSTVHMRKTPSVSLTSVHPDLMKILGDINSDFTRVDEDEEIIVKAMSDYWVVGKKSDRRELYVILNQKNANLIEVNEEVKKLCATQFNNIFFLD
What are the official names of this protein?
Vacuolar fusion protein CCZ1 homolog B, Vacuolar fusion protein CCZ1 homolog-like.
What is the protein family that this protein belongs to?
Belongs to the CCZ1 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: RNPH_CLOPE
Sequence: MRSSGRKKEQIRPVKITRNFTKYAEGSVLIEVGDTKVLCTASIEEKVPPFLKGSGEGWITAEYNMLPRSTQSRKQRDINKLKIDGRTMEIQRLIGRALRSAVDMKALGEKTIWIDCDVLQADGGTRTTSITGSFVALVDAVNKLHQKKPFNVYPIRHFVSAVSVGIVGEEKILDLCYEEDHVAKVDMNVVMTEEGEFIEIQGTGEAGPFSRKELDELLNLAEKGAKQMIQAQKDALKTDSLWIGTGRE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RPIA_PLAF7
Sequence: MDSLKKIVAYKAVDEYVQSNMTIGLGTGSTVFYVLERIDNLLKSGKLKDVVCIPTSIDTELKARKLGIPLTTLEKHSNIDITIDGTDEIDLNLNLIKGRGGALVREKLVASSSSLFIIIGDESKLCTNGLGMTGAVPIEILTFGYEKIIENLLKIYTLKGCTYKIRKRNGEIFITDNKNYIVDFFFTEPIQDLLETCTRIKMTTGVVDHGIFVNMTNVALISKHDGTVLTLNKKYE
What is the function of this protein?
Involved in the first step of the non-oxidative branch of the pentose phosphate pathway.  It catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: ODPA_STAAC
Sequence: MAPKLQAQFDAVKVLNDTQSKFEMVQILDENGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDYILPGYRDVPQIIWHGLPLTEAFLFSRGHFKGNQFPEGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQYEIYKEKESK
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha.
Protein: RL22_WOLSU
Sequence: MSKALLRYIRLSPTKARLVAREVQGMNAELAIASLEFMPNKAAKVISKVIASAVANGGMGAENAVVKSCRVDAGPVLRRFTPRARGRATPIRKPTSHVFVEVVEQSKDK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: OTC_PYRCJ
Sequence: MKHLLTLMEFKPHEVEDLLRISRDFKARYMAGEVYTPLFPGRIVMLYFEKPSTRTRLSLTAAAAQLGMQAVYTAPGELQIGRGETIADTMRVVSRYAAAVAARVYKHETLEEMARYSSIPVINALSDRHHPLQALADALTLWERSGRLHGLKVAFVGDVSNNVATSLAVVGAKLGWEVRLVGPKPLWNQKLVEELAEDLAKTGGQIYFTDSMNEVAGVDGVYTDVWVSMGFEKEAEERRRLLKPYQVNQRVMDIAGKRAVFLHCLPAHRGEEVTDEVIDGPQSAVWDQAENRMHTAKAVFAYLLNKRA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17E_METS3
Sequence: MGNIRTSFVKRLAKELIETHKGVFTTDFDQNKKLVMEYSTVSTKHLRNKIAGYVTRLVRLEQTQE
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: YIHI_MANHA
Sequence: MSRTKKTRRITDIMPARKTDKPKQPMPKLGGGKNRKLTRYELDAQAREEKRKRKHKGLPTGSRNADPAEQKKAVVKEVKDPRIGSRKKVPLMVEFVNQPEKGRTIKAVPVEPIKPTLSPEQELEQLENNECLNQLLDDLEAGKTLSAEDQKFMNECLDRIDELMTELGIEYEDEEGDNGDALLRQFETMDINKFR
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: RRF_BURCM
Sequence: MSVADVKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKNMVAKVEKAIREADLGLNPATAGDLIRVPMPALTEERRRELTKVVKSEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDDVQKLTDKHVAEVDKLVQSKEAEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_CERS4
Sequence: MSYIPFPDISPELFSIELFGVTFALRWYALAYIAGLLIGWRLVLRMIRAERLWSFGPPMTEDQLERLLTWVILGVILGGRLGFVLFYQPAHYLAHPLDILKVWEGGMSFHGGFLGVMTALVAFCLKERISILPVADLLAAATPPGLFLGRIANFINAELWGRPTTLPWGVAFPGEAAQSCPGIEGICARHPSQIYEAGLEGILLFTVLSLLVWRRGWLHWPGSVSGMFLAGYGATRFLVEFVRQPDAQFVSAGNPLGLAWQISGYGLTMGQILSLPMILLGLYLILRSRRTA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.