PharMolix/UniProtQA huggingface dataset:
Protein: Y954_BACC0
Sequence: MNIWLSMLTTTGLGAIIGGFTNHLAIKMLFRPHRPMYIGKFQVPFTPGLIPKRRDELAVQLGKMVVEHLLTPEGIGKKLTNEEFQKGLIHWAQVEVDKVITNEQSLRHMLGKWDVAHVEKEATEKIEQVITEKIQAFLEEYYTYTWEQALPHSVHEKIENAIPNVSAFILKRAIHFFESEEGKSRLSRMIDDFFASRGALLNLVGMFLGNVSVVDRVQPEVIKFLGQDGTKQLLTDVLQKEWEKLKGRDVKELETFVEKEMIVSSILSAVKVEETVSKFLNQSVQQVCEPVRETIIEKVVPNAVTKGLKWGGENVESILNNLHLAEIVQQEVSTFSTERLEDLVLSITKNELKMITYLGALLGGMIGIVQGLLLLFLK
What are the official names of this protein?
UPF0754 membrane protein BCAH820_0954.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COP_ELETR
Sequence: MATYLQASSGPCSTIVPEITRRSANYHPNIWGDQFLKYNSFDLSKTDANTKEHFRQLKEEVKKMLVDAGPNQQLNLIDDIQRLGVAYQFEAEIDAALQRMNVIFQGNDDDLHTISLRFRLLRQHGYNVSSDVFRKFMDNNGKFKECLISDLRGVLSLYEATHFRVHGEDILEDALEFTTSHLERLKSHLKNPLAAQVIRALKCPIHKGLNRLEAKHYISIYQQEDDSHNKVLLNFAKLDFNLLQKMHQGELSHITRWWKELNFAKKLPFARDRVVECYFWILGVYFEPQYLIARRFLTKIIAMASVADDIYDVYGTLEELVILTDAIERWDMGALDQIPECMRVYHRALLDVYTEMEEEMAKTGRPSYRVHYAKEAYKELVRQYLAEAKWFQEDYDPTLEEYLPVALISGGYKMLATHSFVGMGDLATKEAFDWVSNNPLIVKASSVICRLSDDMVGHEVEHERGDVASAVECYMKQYGVTKQEVYIEFQKQISNAWKDMNQECLHPTTVTMPLLTVIFNMTRVINLLYDEEDGYTNSNTRTKDFITSVLIDPVQI
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds (Ref. 1).  Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into alpha-copaene (Ref. 1).  Not active with geranyl diphosphate (GPP) as substrate (Ref. 1).
What are the official names of this protein?
Sesquiterpene synthase Cop, Alpha-copaene synthase, EtCop.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: RL3_ACIET
Sequence: MSLSNSLGLLGRKVGMMRLFTDDGDAVPVTVVDVSNNRVTQVKTQENDGYVSLQVTFGSRKASRVTKPEAGHLAKAGVEAGEIIREFRVTPEVAGKYAAGAAVPVADVFAVGQKVDVQGTSIGKGFAGTIKRHNFGSQRASHGNSRSHNVPGSIGMAQDPGRVFPGKKMTGHLGDVTVTTQNLDVVRIDEARQLLLIKGAVPGSKGGFVTVRPAVKAQASKGAN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PGK_LEPCP
Sequence: MKILRLQDLIAAGQVAGQRVFIRADLNVPQDDAGHITEDTRIRASIPCIEMALKAGAAVMVTSHLGRPTEGEFKPEDSLAPVAARMGELMGREIPVIANWTDGVEVAPGQLVMLENCRLNKGEKKNNEALAQKMAALCDIFVHDAFGTAHRAEASTYGIAQFAKIACAGPLLAAEIDAISLALANPKRPLVAIVAGSKVSTKLTILKALSANVDGLIVGGGIANTFLLAAGLSIGKSLAEPDLVGEARAVIDAMKARGAAVPIPVDVVCAKTFSPTAEATVKAATDVADDDLILDIGPQTAAILAAQLKAAGTIVWNGPVGVFEFDAFAHGTETLARAIAESDAFSIAGGGDTLAAIAKYGIEKDVGYISTGGGAFLEVLEGKTLPAFEILTKRAAG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1258_PASMU
Sequence: MEQPIQPSQHNTKQKRHKSRQRQAAPNVISQIIFASRWLQLPIYLGLIVVQGLYAYKFMKSLWELMTNLQSMDANMIMLAVLNLIDVVMIANLLVMVIVGGYEIFVSKLRTKDHPDEPEWLSHVNASVLKVKLSMSIISISSIHLLQTFVNAANMDEKTMMWQLFLHLGFLVSAVAMAYTDKILYSTSHKGH
What are the official names of this protein?
UPF0114 protein PM1258.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WDR27_MOUSE
Sequence: METPPEMPSTDGHTRAIVTERYVVESKKSAAHVPLACSTQHCAFPLDGSRLCVWSSKDPSHQLLTLQGHHQLITAVVFGNQIDPLLLCSASEDYIIMWNVAECREKTLKGLTPRGTILGSLLQTVLCLRFSLDDRAIAVCAGNKISVMDVEKQSVLVELKGHQGSVTAVEFCPWQAHTLISVSEDRSFKVWDFCVGSLIYSSSILTAYPLLNLLINEENQQLVTGSADGQLWIFSLMEGHHYHCVAHVDVRKKRETFTTRRMMAEQCSLPEDHQCRCRHEADKRGEAEATFPILSLAPCDLCLPDSQRGAFASECTKCLWIGSSTALFILNLASFELEAALHFKEFQSLSVQVAGSCAMVSEPMSAKAFCMLSSMFGSKIAVLEIDLAALLSTQQYPRAGKVLSVLASSCVLPTSPLYFGIIKEKFPKLANTKQHAVKSVVEDRPLVFHTKVRSSGYTLAPHMAMFSPKTNIKHHNKRSSKYKNNYKCKECSLENFLPRNLSRQVAVAQKPVAVSCLQFSGDGQKLACGLGNHLSLVFNASLSGPPAAFSGHDGAVSTICWSHDKRWLLSTGRDRTLRVWSVHRTELMLLLAPDAFPKPVTSAQFYYMDTFILLSSGPEFCLLKYHIDLCRDDIRRYKPKSRYKPIFRLPMTSGADITSLSAVNDFYSHIVLTAGRDRAVEVFDLNAGCSAAVLAEVHSRPVHRICQNKGSSFVAQHSLAYNLFLTAAVGDGIRLWDLRNLRLMCMKWAPAAFCTVLQDTQIRLLKWPSTQQLLSLSQPP
What are the official names of this protein?
WD repeat-containing protein 27.
Protein: Y580_METJA
Sequence: MTKILKVKLMKIALPIDNNRLSPHFGRCEKFMIVEIENGEIKNKEIIENTARNGMHGVGTTSASLIANMGVNAIIVQNIGPKAYSVFKQLGIDVYKANTTSIDECIKLFLEGKLEKFE
What are the official names of this protein?
Uncharacterized protein MJ0580.
Protein: MGDP1_SCHPO
Sequence: MVKNIEFPKCVVFDLDYTLWPLWIDTHVTAPFKPSKNDPGVLIDKYGTEICFYSDITGILQELRNQKVTLCVASRTCAPKYAKQALNLMKVPIDGSLKPAIEFFTYVKAWPGSKMDHFKEIHNESGIDYREMVFFDDESRNREVERLGVTFLEKIKKNSLNILSFLKNHMHG
What is the function of this protein?
Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.
What are the official names of this protein?
Putative magnesium-dependent phosphatase P8B7.31.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YAEH_ECOL6
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: PG176_VACCW
Sequence: MAFDISVNASKTINALVYFSTQQNKLVIRNEVNDTHYTVEFDRDKVVDTFISYNRHNDTIEIRGVLPEETNIGCAVNTPVSMTYLYNKYSFKLILAEYIRHRNTISGNIYSALMTLDDLAIKQYGDIDLLFNEKLKVDSDSGLFDFVNFVKDMICCDSRIVVALSSLVSKHWELTNKKYRCMALAEHISDSIPISELSRLRYNLCKYLRGHTESIEDKFDYFEDDDSSTCSAVTDRETDV
What is the function of this protein?
BCL2-like protein which disrupts the host immune response by inhibiting the TLR4 signaling pathway leading to NF-kappa-B activation.  Acts close to the plasma membrane and targets several host TIR-domain containing adapter proteins including MYD88, TIRAP, TRIF and TICAM2.  In turn, blocks the host NF-kappa-B and TRIF-mediated IRF3 activation.
What are the official names of this protein?
Protein OPG176.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG176 family.
Protein: PSBN_PINTH
Sequence: METATLVTISISCLLVSFTGYALYTAFGQPSKQLRDPFEDHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y935_SYNJA
Sequence: MASTYSFDIVSDFDRQELVNAVDQARREIKQRYDLKDTQTEIELEEGSLIITTASEMALNSIRDLLLTKAAKRGLSLKIFDFQPPESAGGNRVRQVVRLKKGIDAALAKQIAKQIRDNFKKVQPSIQGDLVRVSGKDKDELQAVIQMLKQQDYPVALQFVNYR
What are the official names of this protein?
UPF0234 protein CYA_0935.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: TYRO3_CHICK
Sequence: MELRRSMALPRLLLLGLWAAALRDGAVAAGMKFTGSPIKLKVSQGQPVKLNCSLEGMEDPEMLWIKDGAVVQSVDQVYIPVDEDHWIGFLSLKSVERTDSGKYWCQVENGGKKEESQQVWLIVEGVPYFTVEPEDVSVSPNAPFHMACAAVGPPEPVTIVWWMGDSRVGLPDISPSILNVSGINQSTMFSCEAHNVKGLSSSRTATVQIKAMPLPPLNVTVSQVTSSNASVVWVPGFDGRAPLHSCTLQVAESPDGQEVSTEVAPVPPFAYGVQGLKHSTNYSVRVQCSNEMGSSPFTERVYFQTLELAPSSTPQNIHVIQRDPGLVLEWEGVAPDVLKENVLGYRLEWIQDNVTQGEMIVQDTKANLTTWNPLKDLIIRVCVLNSAGCGPWSDLFLLEAQEVMGGQRQPPYGTSWVPVALGILTALVTAVALALILLRKRRKETRFGHAFGSVVGRGDPAVHFRAARSFNREGPELIEATLESVGISDELKTKLKDVLIQEQQFTLGRMLGKGEFGSVREALLKLDDGSFQKVAVKMLKADIFTSTDIEEFLREAACMKEFDHPHVTKLIGVSLRSRPKGRLPIPMVILPFMKHGDLHAFLLMSRIGENPFNLPLQTLLKFMIDIASGMEYLSSKNFIHRDLAARNCMLDENMNVSVADFGLSKKIYSGDYYRQGCASKLPVKWLALESLADNLYTTHSDVWAFGVTMWEIVTRGQTPYAGIENAEIYNYLISGNRLKQPPECLEDVYDLMCRCWHPEPKLRPSFGVLRSQLEMIRGRMSTLSLSQDPLYVNIGKDKESSVSDPAVHTSFGNTDGDETIAGAAAAAITSDYRYIMSPLCLGDDVEGERHPEGQEGENKSLLYELETEGEKSC
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands.  Regulates many physiological processes including cell survival, migration and differentiation.  Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, enhances PI3-kinase activity and activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase receptor TYRO3, Retina-expressed kinase, Rek.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: BUK_CLOB8
Sequence: MSYKLLIINPGSTSTKIGVYEGEKELFEETLRHTNEEIKRYDTIYDQFEFRKEVILNVLKEKNFDIKTLSAIVGRGGMLRPVEGGTYAVNDAMVEDLKVGVQGPHASNLGGIIAKSIGDELNIPSFIVDPVVTDELADVARLSGVPELPRKSKFHALNQKAVAKRYGKESGQGYENLNLVVVHMGGGVSVGAHNHGKVVDVNNALDGDGPFSPERAGSVPIGDLVKMCFSGKYSEAEVYGKAVGKGGFVGYLNTNDVKGVIDKMEEGDKECESIYKAFVYQISKAIGEMSVVLEGKVDQIIFTGGIAYSPTLVPDLKAKVEWIAPVTVYPGEDELLALAQGAIRVLDGEEQAKVY
What is the function of this protein?
Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate.
What are the official names of this protein?
Butyrate kinase, BK.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSM3_CAEEL
Sequence: MAESVRVAVRCRPFNQREKDLNTTLCVGMTPNVGQVNLNAPDGAAKDFTFDGAYFMDSTGEQIYNDIVFPLVENVIEGYNGTVFAYGQTGSGKTFSMQGIETIPAQRGVIPRAFDHIFTATATTENVKFLVHCSYLEIYNEEVRDLLGADNKQKLEIKEQPDRGVYVAGLSMHVCHDVPACKELMTRGFNNRHVGATLMNKDSSRSHSIFTVYVEGMTETGSIRMGKLNLVDLAGSERQSKTGATGDRLKEATKINLSLSALGNVISALVDGKSKHIPYRDSKLTRLLQDSLGGNTKTIMIACVSPSSDNYDETLSTLRYANRAKNIKNKPTINEDPKDALLREYQEEIARLKSMVQPGAVGVGAPAQDAFSIEEERKKLREEFEEAMNDLRGEYEREQTSKAELQKDLESLRADYERANANLDNLNPEEAAKKIQQLQDQFIGGEEAGNTQLKQKRMKQLKEAETKTQKLAAALNVHKDDPLLQVYSTTQEKLDAVTSQLEKEVKKSKGYEREIEDLHGEFELDRLDYLDTIRKQDQQLKLLMQIMDKIQPIIKKDTNYSNVDRIKKEAVWNEDESRWILPEMSMSRTILPLANNGYMQEPARQENTLLRSNFDDKLRERLAKSDSENLANSYFKPVKQINVINKYKSDQKLSTSKSLFPSKTPTFDGLVNGVVYTDALYERAQSAKRPPRLASLNPK
What is the function of this protein?
Kinesin motor protein which is required for the anterograde intraflagellar transport (IFT) along the middle segment of the sensory neuron cilia together with the kinesin II motor complex (composed of klp-11, klp-20 and kap-1) and on its own, is required for IFT along the distal segment (PubMed:17000880, PubMed:17420466).  In addition, regulates the length of cilia (PubMed:17420466).  May have a role during neurogenesis and axonal transport (PubMed:7714894, PubMed:7690265).
What are the official names of this protein?
Osmotic avoidance abnormal protein 3, Kinesin-like protein osm-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes along the full cilium length.
Protein: TRHO_STAAT
Sequence: MNYQVLLYYKYMTIDDPEQFAQDHLAFCKAHHLKGRILVSTEGINGTLSGTKEETEQYMAHMHADERFKDMVFKIDEAEGHAFKKMHVRPRKEIVALDLEDDVDPRHTTGQYLSPVEFRKALEDDDTVIIDARNDYEFDLGHFRGAIRPNITRFRDLPDWIKENKALFADKKVVTYCTGGIRCEKFSGWLLKEGFEDVAQLHGGIATYGKDPETKGEYWDGKMYVFDDRISVDINQVEKTIIGKDWFDGKPCERYINCANPECNKQILVSEENETKYLGACSYECAKHERNRYVQANNISDNEWQQRLTNFDDLHQHA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RS3_BREBN
Sequence: MGQKVSPVGLRIGVIRDWESKWYADKDFATLLHEDLKIRKYVKGRLKDAAVSTIEIERAANRVNVTIHTAKPGMVIGKGGSEVETLRKTLTDLTGKRVHININEIKRPDLDATLVAENIARQLENRISFRRAQKQSITRTLRSGAKGIKTLVSGRLGGADIARSEGYSEGTVPLHTLRADIDYGTAEAHTTYGRIGVKVWIYRGEVLPARKNVATEEGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SYY_THEVB
Sequence: MSSDLEATIARLQRGVVETFPHVPDSVKPEENLWAYLRQTQRPLRIKFGIDPTGSEIHLGHSIVLRKLRQFQDAGHCAVLIIGDFTAQIGDPTGKSEVRKQLTPEEVAANVQTYLEQVRPILDFETPGRLEIRYNSEWLAKLDLRKVLELLGTMTVGQMLAKEGFAERYAKETPIFLHEFLYPLMQGYDSVAVAADVELGGTDQKFNIAVGRDLQRHFRLPTVQFGLLMPILVGTDGVQKMSKSLGNYVALTESAASMYSKLEKIPDALVNQYIELLTDLPLDSLPTHPRDRQKALALAVVSQYHGQELALQTQAELAAIVTQGQTAQAGSIPEYSLGEFQFPVKLTYVLSHTKLCPSSSEARRQIQGGGVRLNGEKITDVDFTLTAPEPYVNQVLQVGKKKFLRFVP
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_AQUAE
Sequence: MLNYELELWEKGLLVAGVDEAGRGPLAGPVVAAAVILPPFTEPFIKGDSKKLTKKEREEAYEEIKNKALAVGTAVVDSAVIDRVNILRATKLAMKRALKDLKYHYDIVITDYVKLEGENCMPLVKGDEKSLNCACASIIAKVIRDKIMEIYHKIYPDFNFASNKGYPSKTHLEKVEKGEYTEIHRKSFSPLKKKLF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JCAD_HUMAN
Sequence: MYSVEDLLISHGYKLSRDPPASREDNPKGRQAARTGTRAGQGLQNGHEDGPAALAHRKTSAGKGHVSDSESRRSTPRGHGEPQSTSASRTSEAGFCNQPPSAWSSHPPTGNDQAYRRRGRQEARSQKPREHENLEARGMAQAHSLPVHVREGPWEVGGRSEHVMKKPVWEEELRMSGPAKWQNVSLESWNQPRKLGRQMSDGDGERLFQDLYPFIQGEHVLNSQNKGKSRSLPRVLSPESLSCTEIPIPLNERHSPKMPPYPPTCAPNLDSTRNSEKSGCSAPFPRPKFGRPLKPPSYSSHQQSRGGADSSDSQDSQQMDAYVPRHELCLSDPGLEPPVYVPPPSYRSPPQNIPNPYLEDTVPINVCGGHSQQQSPTEKAGASGQPPSGPPGTGNEYGVSPRLPQGLPAHPRPVTAYDGFVQYIPFDDPRLRHFKLAQPQGFCEDIKLDDKSYNSSPVTAQEPAHGGMQPDGAIWNPQSLIPPSGDERGLVLADSSPRWLWGQPPGDGENSGLPNQRDRCVARGQWPDVRGSQHGHTGRQVSSPYSQGESTCETQTKLKKFQTGTRTKKSSKKKMNETIFCLVSIPVKSESHLPDRDMDNNDLKPSADQKNGSDKSPALQEQSLLSMSSTDLELQALTGSMGGRTEFQKQDLGEPEEDRQTNDLSFIHLTKHRELKHSGSWPGHRYRDQQTQTSFSEEPQSSQLLPGAKLGGPSRAALSPKCSDPAASEAQTHTAFPTGDHKQRPSARNLKGHRSLSPSSNSAFSRTSLSVDQAPTPKAGRSQPCVDVHGLGAHPGPKREVVKGEPTGPCNSKQLFGQFLLKPVSRRPWDLISQLESFNKELQEEEESSSSSSSSSSSSEESEAEPQQENRAHCRQEDVGFRGNSPEMRVEPQPRMWVPESPVCRSGRGESKSESWSEELQPGHPRAWPPSPGRFRVEEGGGAPFCSADGSTSAEKRHLEVSNGMDELAGSPFPVTRMSSRSSDAKPLPASYPAEPREPQESPKITSAFSSVKPSEAVPRKFDSGGERGAGLPLSLSNKNRGLSAPDLRSVGLTPGQEQGASELEGSLGEASTIEIPPGESLQARAARILGIEVAVESLLPGIRRAGQNQPAEPDASACTPESPQEELLSRPAPADVPRVSTDAFYGRRKCGWTKSPLFVGDRDSARRAPQAFEHSDVDGVVTSTDPVPEPEPSPLESKFFEQKDVETKPPFRSTLFHFVERTPSVAGSEKRLRSPSKVIESLQEKLASPPRRADPDRLMRMKEVSSVSRMRVLSFRNADSQEDAEELKATTRGQAGLPGGLVSPGSGDRAQRLGHSLSVSKDSISREEKEHPAAQKEKSMDQDFWCPDSYDPSRVERV
What are the official names of this protein?
Junctional cadherin 5-associated protein, Junctional protein associated with coronary artery disease, JCAD.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Note=Colocalizes with CDH5/VE-Cadherin in endothelial cells but not in epithelial cells.
Protein: NDK_YEAST
Sequence: MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVKADDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAPGTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (PubMed:5793714).  Required for repair of UV radiation- and etoposide-induced DNA damage (PubMed:18983998).
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space. Note=Localizes predominantly to the cytoplasm. A small fraction is present in the mitochondrial intermembrane space.
Protein: OR1A2_HUMAN
Sequence: MKKENQSFNLDFILLGVTSQQEQNNVFFVIFLCIYPITLTGNLLIILAICADIRLHNPMYFLLANLSLVDIIFSSVTIPKVLANHLLGSKFISFGGCLMQMYFMIALAKADSYTLAAMAYDRAVAISCPLHYTTIMSPRSCILLIAGSWVIGNTSALPHTLLTASLSFCGNQEVANFYCDIMPLLKLSCSDVHFNVKMMYLGVGVFSLPLLCIIVSYVQVFSTVFQVPSTKSLFKAFCTCGSHLTVVFLYYGTTMGMYFRPLTSYSPKDAVITVMYVAVTPALNPFIYSLRNWDMKAALQKLFSKRISS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 1A2, Olfactory receptor 17-6, OR17-6, Olfactory receptor OR17-10.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNP_PSYA2
Sequence: MTMFNTIKREFQYGNQQVVIETGRIARQANSILVHMGGVTVLVAAVVKSDAKEGQNFFPLTVNYQEKMYAAGKIPGAYGKREGRASESETLTSRLIDRPIRPLFPEGYVNEIQITATVVSSDKTQSADIAALIGASAALAISDAPFNGPVAAARVGFINGEYVLNPTLEELKESDLDLVVAGTKSAVLMVESEAAELSEDQMLGAVLYGHQQQQIVIDNIASMAAEIGTAKQQYTAPVRDQALETGMKEQFGAQVSDAYTITDKQARYSKLNEIKDAAIVALAGDAESESYSDTVSELKEIYNDLKYRTVRDNILSGKPRIDGRDLETVRALDVQVGVLPFTHGSALFTRGETQALVTTTLGNTRDVNMIDSLAGTIRDHFMLHYNFPHFSVGETGREGIPKRREIGHGRLARRGVQAMLPDSDRFPYVIRVVSEITESNGSSSMASVCGASLALMDAGVPIKAPVAGIAMGLVKEGERFAVLSDILGDEDHLGDMDFKVAGSKDGITALQMDIKIEGITPDIMEQALKQAHAGRIHILDAMNKVLPESRTEINAHAPNYAVIEINPDKIRDVIGKGGATIRQLTEETGAVIDIDDAGTIRIFGENKAATKAAIAKIEAITAEVEVGKTYEGTVARIVDFGAFVNVLPNTDGLVHISQIADERVENVSDYLKEGQIVKVLVQDVDNRGRIKLTMKGIEQS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_SYNC1
Sequence: MNIIDRLEMEQMKKDIPAFKAGDTLRVHVKIVEGDKRRIQVFQGVCIKRHNKGLGSTFTVRKISDGMGVERVFPLHSPNIDKIEVMMVGRVRRAKLYYLRKLQGKAARIREKRSL
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PUR9_YERPY
Sequence: MQQRRPIRRALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPPYHGDTEQPSGHFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVATAQQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDSILAAYERAYQTDPTSAFGGIIAFNRELDAATANAIISRQFVEVIIAPTVSSDALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGLLVQERDLGMVTAADLRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHGIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RL34_PSEF5
Sequence: MKRTFQPSTIKRARTHGFRARMATKNGRAVLSRRRAKGRARLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LONP2_CAEBR
Sequence: MKFEESMELPVIVVDSGVLLPGASLKIPIRSKLNTRTIEQHLTRGGSNYVVIAYKLSTDKIYNVATIAYIEKLFGWTFNSTTNYSLDVIGLHRANIDKLSFPKCRVSKLEDSSERAEFNHSTIENVISGAKILAQNSESLKFSQEIHNSIDDHDYGKLADLCVSQIKNLEFSQFLDFLGTKNVEKRLEMCEKWMQMQRETKALQLKMAVPGNSEIPKKINKQRIPNSKNQVEQLEEKLSAIEFSEEVSDRVFSELHRLKNMNPQQSEYTVLMNWLELVSNLPWNTSTVDDIEINKARKILEDSHESMDDVKQRVLEHLAVCKINNSVKGMILCFTGPPGIGKTSIAKAIAESMGRKFQRVSLGGIRDESDIRGHRRTYVAAMPGRIIEALKHCKSNNPVFLLDEVDKLYSGNQGSPSAALLELLDPEQNSTFHDHYLNIPFDVSKIMFIATANDVERLEPALKDRLEIIEMSGYSMKEKVKICENHLVNRQLSKHCISPDYVNLDRHAIMAMIEEFTMEAGVRQLERNVGAVCRHVALRLAEALNSDPSADVLPDMDLPIQIGEPDIHKILKAKHMKRVKIVEKMRPLPPGVCFGLSVTTNGGRVMPIEASKCKGTGKIVTTGHLGKVLEESILVAKGWLGANAEKLGLKTLEENDIHVHLPAGAVNKDGPSAGTGLACALVSLAMGVPLRSDAAVTGEISLTGHVLAIGGVKEKVLAAQREGLRRVVLPKSNEEEYLKIDEDIRNEMDVVLADTVEDVIEAMMEKEPVLAKL
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix.  Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
What are the official names of this protein?
Lon protease homolog 2, peroxisomal.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: CSRA_WOLSU
Sequence: MLILSRKEEESIVIGDEIVIKVVSIDKGSVKLGFEAPPHMLILREELKKAVADENLKASAQSDEIALTSLSQKLKK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPOB_SHISS
Sequence: MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPAEPQQPVPTVPSVPTIPQQPGPIEHEDQTAPPAPHIRHYDWNGAMQPMVSKMLGADGVTAGSVLLVDSVNNRTNGSLNAAEATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGTRSKAIGIARNVGAHYVLYSSASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).
What are the official names of this protein?
Penicillin-binding protein activator LpoB, PBP activator LpoB.
What is the protein family that this protein belongs to?
Belongs to the LpoB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: PANB2_BRADU
Sequence: MSHSSEQPLERVTIPALQQWKDKGRRVVMTTAYDAVAARIADPIVDIILVGDSVGNVCLGFDNTLPVSVAMMNHHLEAVARTRPHALLVADMPFLSFHVGSEDTIRNAGGFLQRGADAVKLEGGAKRIEMVRALVDCDIPVMGHLGLTPQSVNVMGGFKVQGRTTDTALRLLDDAHRLQEAGCFALVLEGIPAELAARATESLTIPTIGIGAGADCSGQVLVFHDVLGLTEGHRPKFVRAYTNGFQLFQEALSRWAADIRKGAFPGSEECYRLPDQLRHAVANWVPSSSTSR
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 2, Ketopantoate hydroxymethyltransferase 2, KPHMT 2.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.