PharMolix/UniProtQA huggingface dataset:
Protein: CARP_ARTBC
Sequence: MKGSLLLAGATLLGCTSAKLHSLKLKKVSLKEQLEHADIDVQIKSLGQKYMGIRPEQHEQQMFKEQTPIEVESGHNVLIDNFLNAQYFSEISIGTPPQTFKVVLDTGSSNLWVPGKDCSSIACFLHSTYDSSASSTYSKNGTKFAIRYGSGSLEGFVSRDSVKIGDMTIKKQLFAEATSEPGLAFAFGRFDGIMGMGFSSISVNGITPPFYNMIDQGLIDEPVFSFYLGDTNKDGDQSVVTFGGSDTNHFTGDMTTIPLRRKAYWEVDFDAISLGKDTAALENTGIILDTGTSLIALPTTLAEMINTQIGATKSWNGQYTLDCAKRDSLPDVTFTLSGHNFTIGPHDYTLEVSGTCISSFMGMDFPEPVGPLAILGDSFLRRYYSVYDLGKGTVGLAKAK
What is the function of this protein?
Vacuolar aspartic endopeptidase which is probably also secreted and contributes to virulence.
What are the official names of this protein?
Probable vacuolar protease A, Aspartic endopeptidase PEP2, Aspartic protease PEP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Vacuole lumen. Secreted.
Protein: ATG9B_MOUSE
Sequence: MVRRTGWGGSRRQRGRWGDLGPSSVPLLPMALPLPASPCRGTGGRRISVFSLSPAPRTRSCSSSVFPPASGSPCLVIQEAGASQTPHNVLPTPTTPSTQAHPTMIHTSASPSWGSHSTPPLASATPPPSCPRPQDHPGLRMGPLIPEQDYERLEDCDPEGSQDSPIHGEDHQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFNNQPKNHTRRGPLHSKVTLSDAILPSAQCAEKIHDSPLLVFLLVLAAGFWLFQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLELQRSGGLCVQPRPLTELDVHHRILRYTNYQVALANKGLLPARCPLPWGSSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPEAYKRSDLRGVLANRWRRTVLLLAAVNLALSPLVLAWQVLHAFYSHVELLRREPGAFGARRWSRLARLQLRHFNELPHELRARLGRAYRPAAAFLRAAEPPAPLRALLARQLVFFSGALFAALLVLTIYDEDVLAVEHVLTTMTALGVTATVARSFIPEEQCQGRSSQLLLQAALAHMHYLPEEPGATGARASSYWQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSEGQTEASLSQRAEDGKTELSLMRFSLAHPQWQPPGHSSKFLGHLRGRVQQDAAAWGAPSTRSPPTPGVLSDCTSPLPEAFLANLLVNPRPPQRDLSPTAPCPAAATASLLASISRMVQDPSCVSPGGTGGQKLTQLPELVSAEMSLHAIYLHQLHQQQQQELWGEASASSPSRPWSSPSQPGSPDEEKPSWSSDGSSPASSPRQQWGTQRAQNLFPKGFQENTDTQKEPLTGPLH
What is the function of this protein?
Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion (PubMed:15755735).  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion (By similarity).  In addition to autophagy, also plays a role in necrotic cell death (By similarity).
What are the official names of this protein?
Autophagy-related protein 9B, APG9-like 2, Nitric oxide synthase 3-overlapping antisense gene protein.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistribution depends on ULK1 and ATG13.
Protein: FOLB_MYCBO
Sequence: MADRIELRGLTVHGRHGVYDHERVAGQRFVIDVTVWIDLAEAANSDDLADTYDYVRLASRAAEIVAGPPRKLIETVGAEIADHVMDDQRVHAVEVAVHKPQAPIPQTFDDVAVVIRRSRRGGRGWVVPAGGAV
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin, 7,8-dihydromonapterin and 7,8-dihydroxanthopterin, respectively, in equal quantities.  After longer incubation times the only product is 6-hydroxymethyl-7,8-dihydropterin.
What are the official names of this protein?
Dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin 2'-epimerase, 7,8-dihydroneopterin aldolase, 7,8-dihydroneopterin epimerase, 7,8-dihydroneopterin hydroxylase, Dihydroneopterin epimerase, Dihydroneopterin hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: PUS4_ORYSJ
Sequence: MAALLYLRRRAAAAALAGVAPKPQWLATAARRGALVSGDDGGETGERGKSPWLQLPPFAPLDAAAAARAISRGGGEGGDGEQGATAIKWVRRCCPDLPTSLVQKLFRLRKVKKNVVTAEISSADASAEQHRLRRVSAKDQLMPGDILFLPVNLKESSVAEKTKKFDNRNEINFLRGLEIYKDEAIIVVNKPPGMPVQGGVGIKNSIDVLASMFEENSSEAPRLVHRLDRDCSGILVLGRNQLSTSMLHAIFREKTADALADGTQHVLQRKYVALVIGTPRHPKGLLSAPLAKILLQDGKSERLTIRASSNAASVQDALTEYRVIESCPQGYTWLELFPRTGRKHQRFLEPQLLGITSMDGKRIRSGCLFPCHGQLMRNCSGKGSFPLGLLWVAEASLRSNLSFIYTASKWFFLMSQWLFIGCSLQTLILISQILRSSTLLLHCRCICG
What are the official names of this protein?
RNA pseudouridine synthase 4, mitochondrial, RNA pseudouridylate synthase 4, RNA-uridine isomerase 4.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL14_RHOE4
Sequence: MIQQESRVRVADNTGAKEILCIRVLGGSSRRYAGIGDVIVATVKDAIPGGNIKKGEVVKAVIVRTTKERRRPDGSYIKFDENAAVLIKADSDPRGTRIFGPVGRELREKKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL9_FINM2
Sequence: MKVILTSDVDKLGKAGEMVNAKTGFARNFLLPNKLAVQATKENIKIWEEKQAELRAIERENIKKANELKEKIENTKVKIIAKTGEGDRLFGSITSMDIEKALKEQHGLDVDKKKIEMKDNIKSLGTFNVVVKVYPDINANLEVIVDKE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: KLF14_MOUSE
Sequence: MSAAVACLDYFAAECLVSMSTRAVLHRRATDPEGASAAAVSEVGAVSRESAGKGTGSRGVLWIPPVLQVPTPSPGEGDGAPHLLAASALADLSCGAREDFREDSEEAPCASTSCFEPTWCSSPTGGSEPTQAFFEDELSDAESSCSDSAILDAPEASEEPDDSGEVPEGPPGARPAPSTGPTYRRRQITPASKRHQCSFHGCNKAYYKSSHLKSHQRTHTGERPFSCDWLDCDKKFTRSDELARHYRTHTGEKRFSCPLCPKQFSRSDHLTKHARRHPTYHPDMIEYRGRRRTPRPEPPPPAMVESSGSDSSSSSGQETSFTACL
What are the official names of this protein?
Krueppel-like factor 14.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACKA_CLOD6
Sequence: MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHEKAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFATSVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSSYLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAAVDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVYGMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVGENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARDTLRLVK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_SHEFN
Sequence: MAKKRPLALLILDGWGYSEDTQDNAVFHANTPVLDKLNAQYPHSLISGSGIDVGLPDGQMGNSEVGHINIGSGRIVYQELTRISKAIADHEFEQNAALCDAVDKAIAANGAVHIMGLLSAGGVHSHEEHIEAMCRMAVERGATKVYLHAFLDGRDTPPRSAKNSLVHFDELFASLGHGRTASIIGRYFAMDRDNRWDRVSQAYELITEAKGKFTYASAPEALEAAYARDENDEFVAASAIVDAQGEAAVLSDNDSLIFMNFRADRARQITRTFVNPDFDGFKRNKTPKINFVMLTDYAADINAPVAYPSSDLVNTLGETLQNLDKTQLRISETEKYAHVTFFFNGGKEEPFEGEDRILIQSPKVATYDLQPEMSSTELTDKLVAAIESTKYDVIICNYPNGDMVGHSGNFDAAVKACEAVDACIGRVVEALAKVDGECLITADHGNAEKMKDPSNGQAFTAHTSNLVPFVYVGRDAVIKDGGRLSDIAPTMLTLMGQSIPKEMSGRCIIDLKE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: LDB18_YEAST
Sequence: MPGLKLVEALEYRCDRLERLIGAGYSANSDVSVQLDELYNQLHRLYFQGLKYSQDLLQLFNTFMAEDIENVGAPDDICIFASCFDDIYTLYSAFDELNSQYMEFCQISKSSLDQISFKDANIETKQLKKLPELVDNCNIMILRSIAILNRFIDWNIEVNGFFQFQKKRLLNLQKVIYST
What is the function of this protein?
May be involved in protein-linked oligosaccharide phosphorylation since the deletion reduces the negative charge of the cell surface.
What are the official names of this protein?
Protein LDB18, Low dye-binding protein 18.
Protein: ACLS_ASPOR
Sequence: MTTVIRYGTRLEHLHEAVKLSPHGQTALSVWINDDIRPLPPSRRTWSTMTFIGWWSVWQLSLTNWQLGGSLVASSLSVWQTMVAVVLGRTIAAIVAILIGYIGAEWHIGFPVYSRAIWGVFPYSCHRTVPRQSNVGVILKGAFFPTLLRIGLTVVGFAFQSYTGGLCVTAILSGIFPTFFRMSNTLPASAHVTTQQIIGWAIFNIISIPVLYRRPERSEKLMIGMNIMSFAALLGIMIWSLSHAHGAGDLIHQPSQLQTSDSLGFGIMQGITTVVGTLSIALSRSPFVYPYLKYVSDLDSASQMDFSRFARKPSDQVFGQWFTFIIIGSIMPLFGCLTSSATQAIYGEALWNPPTILAISTSRAAAVFAGIGLVSSQLALNVVDNGKSSPSQSVKGFSNYPVGYSVGMDLSGLLPKYINIRRGCYVGLILGMALCPWELLASATTFVSVISSFSIFMAPFCGIHISDYWFIRQRRLKLSDLYHARPEGIYFYTMGFNWRGVLPWLVGWVPLLPGFMHSINPAIKVSVGADHLYALGFPYGLLSSMAIHTLVNKCFPPPGIGEIDRDDTYGTFTVEEAAKLGVNKDSTEEDSDRSLRRESREVVETKV
What is the function of this protein?
Transporter; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).
What are the official names of this protein?
Transporter aclS, Aspirochlorine biosynthesis protein S.
What is the protein family that this protein belongs to?
Belongs to the purine-cytosine permease (2.A.39) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SARR_STAAM
Sequence: MSKINDINDLVNATFQVKKFFRDTKKKFNLNYEEIYILNHILRSESNEISSKEIAKCSEFKPYYLTKALQKLKDLKLLSKKRSLQDERTVIVYVTDTQKANIQKLISELEEYIKN
What is the function of this protein?
Negative regulator of sarA transcription at late exponential and stationary growth phases.  It contributes to the modulation of target genes downstream of the sarA regulatory cascade.  Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarR, Staphylococcal accessory regulator R.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHCG_RABIT
Sequence: MAWNTNLRWRLPLLCLVLEVAMVVLFGLFVRYSPDADSSWSNEKRKGNITSDLENEFYYRYPSFQDVHVMVFLGFGFLMTFLQRYGYCALGFNFLLAALGVQWALLMQGWFQYTKDRLILLGIKNLIDADSCVASVCVAFGAVLGKVSPVQMLLMTFFQVALFSANEFLLLHVLEVKDAGGSITIHIFGAYFGLTVTWILYRHNLDHSRERQSSVYHSNLFAMIGTLFLWIYWPSFNSAMSNYGDAQHRAAINTYCSLAASVLTSVAMSSVLHKKGKLDMVHIQNATLAGGVGVGTAAEMMLMPYGALIVGFICGAVSTLGFVYLTPFLESRLRIQDTCGIHNLHGIPGLIGAIVGAVTAAYASPDGDRGFVYPFGFHNEKDEKVQGRFQAFGLLLTLAIAMVGGTIMGLILKLPFWGQAMDEDCFDDSIYWEMHEEKSSSPEDHTHKPSVPTEPVEQPTSSATLAP
What is the function of this protein?
Ammonium transporter involved in the maintenance of acid-base homeostasis.  Transports ammonium and its related derivative methylammonium across the plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism.  Postulated to primarily mediate an electroneutral bidirectional transport of NH3 ammonia species according to a mechanism that implies interaction of an NH4(+) ion with acidic residues of the pore entry followed by dissociation of NH4(+) into NH3 and H(+).  As a result NH3 transits through the central pore and is protonated on the extracellular side reforming NH4(+) (By similarity).  May act as a CO2 channel providing for renal acid secretion (By similarity).
What are the official names of this protein?
Ammonium transporter Rh type C, Rhesus blood group family type C glycoprotein, Rh family type C glycoprotein, Rh type C glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Also detected at the basolateral membrane and in subapical vesicles.
Protein: MURB_MYCGI
Sequence: MGTSLLGGVPVAENVPLAPLTTLRVGPVARRLVTCVTTDQIVDAVMAAGPEALILAGGSNVVLAGDAADLTVVRLANTRISVDGDVVRAEAGAGWDDVVAASLAHGLGGLECLSGIPGSAGATPVQNVGAYGAEVADTIRRVRLLERGTGSVRWVSPEFLRFGYRTSVLKHSSQWVVLEVEFGLDAAGHSAPVRYRELATELAVEQGERTDPQRVRAAVLELRARKGMVLDAADHDTWSVGSFFTNPVVSRAEFERIAATVGSAVPNYPAEDGVKLAAGWLVEQAGFGKGYPGADAPARLSTKHALALTNRGTATTADVLALARTVRDGVKAAFGIELTPEPVLVGCSL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIL2A_HUMAN
Sequence: MAASAALSAAAAAAALSGLAVRLSRSAAARGSYGAFCKGLTRTLLTFFDLAWRLRMNFPYFYIVASVMLNVRLQVRIE
What are the official names of this protein?
Small integral membrane protein 10-like protein 2A.
Protein: TIG_RICFE
Sequence: MGITVLKNEGLDFHARISTPLSEIDDDIQKELLDLTKKVKIAGFRAGKVPVSIVKKKYGTSVRNDIIERRINHSVNHVIKEHNLNIIGRPKIEELQNEPDKALEFTVKIELLPKITIPDLKKISLDRPKLEVNSKDVEEQLEKLAALTKSYTKESKAKIKDGVQVTIDAIGYIKDEAFEGGKLNDFKVVIGSNALIPGFEKQLIGSKTGSEVDVNVTFPENYHAKDLAGKDARFAVQIKSVHTAEPTVIDEEFAKKFQSNSLEELRTHFAKQIENESEEAINTIMKMNLFDKLEKLLDFDVPESLLEQEKNILKSETDKNDQDESLLKDKSPKEITEYYNKLALRRVRIGLLLAEYAKSKNLQLEPDDLRKVIMQQARNFPGQENMIFDFYKNNPRAIEGLKGPALEDKAVQYIFNNEIKLKEKKYTKEELEKYLEAEEQRITLI
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: TGAL1_ORYSJ
Sequence: MEGGRLGGAAASASAAAAADARGGMSGFAAPQHAIHTNLNNVQPTQVTDFGALAQSAGFRIEDLANLSTNGLFNLKSNAHTIINDPLQFENYVKSISPSNITTTATVTVVDPQTLVPQKGAQLNLVTIRTGNVENWGESTIADTSPRTDTSTDPDTDERNQMFEQGQLAAPTASDSSDRSKDKLDHKTLRRLAQNREAARKSRLRKKAYIQNLESSRLKLTQIEQELQRARQQGIFISTSSDQSHSASGNGALAFDMEYARWLEEHNKHINELRAAVNAHAGDNDLKSTVDSIMAHYNEIFKLKGVAAKADVFHVLSGMWKTPAERCFMWLGGFRSSELLKLLAGQLEPLTEQQLAGIANLQQSSQQAEDALSQGMEALQQSLAETLASGSLGPAGSSGNVANYMGQMAMAMGKLGTLENFLRQADNLRLQTLQQMQRILTTRQSARALLAISDYFSRLRALSSLWLARPRE
What is the function of this protein?
Transcriptional regulator involved in defense response.
What are the official names of this protein?
Transcription factor TGAL1, OsNIF4, bZIP transcription factor 8, OsbZIP08.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSPLT_ORYSI
Sequence: MRASRPVVHPVEAPPPAALAVAAAAVAVEAGVGAGGGAAAHGGENAQPRGVRMKDPPGAPGTPGGLGLRLVQAFFAAAALAVMASTDDFPSVSAFCYLVAAAILQCLWSLSLAVVDIYALLVKRSLRNPQAVCIFTIGDGITGTLTLGAACASAGITVLIGNDLNICANNHCASFETATAMAFISWFALAPSCVLNFWSMASR
What are the official names of this protein?
CASP-like protein 5A2, OsCASPL5A2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EIF3A_EMENI
Sequence: MPPPPHIKPENVLKRAQELIAVGQAPAALTVLHEHATSKRTRSSPIASLEPVMLLFVELCVDLRKGKAAKDGLYQYKNIAQNSNVGTIEIVLKKFIELAEKKVTEAQAKADEIQSSLESAAPSSNVEDLEAIETPETILLATVSGEQSRDRTDRAVVTPWLKFLWETYRTVLEILKNNARLEIMYQTTALQAFQFCLKYTRKTEFRRLCELLRNHVQNAAKYSAQMHAINLSDPDTLQRHLDTRFQQLNVAVELELWQEAFRSIEDIHTLLSLSKRPAKNVMMANYYEKLARIFLVSENYLFHAAAWSRYYNLLRQSAVTLSTNQGSKKDHPSVTEADMTKAASFVLLSALAIPVISTSRSRGALIDVDEVRKNKNTRLTNLLGMLQSPTRAVLFRDALNKGLLKRVRPEIRELYNILEVDFHPLSICKKVTPILKKIGDDPEMEKYVVPLQQVILTRLFQQLSQVYESVELKFVYELAQFPDPFQITPSMIEKFIMNGCKKGDLAIRVDHISGVLTFDTDVFSSAKALHSGSAAGSAESELGSVQRLQNTPAEIARLQLTRLAKTLHVTCMYVDPSYNDSRLQAKQAALTRAAAGAAKEHEDTLERRVIIEKKKEAATDALQRKQKEEETRKRIRTQQLQEAEKQRLAEEQRERELKRIKDEQDRIRQQELKKQLEELKSGVKGIDLNEIDLEDLDANRLRAIKLAQLEKEKNELTERVRATGKRIDHLERAFRREELKHIAEDYEAQKKVDMEIYERQKAQTLAEAEAKHKEAVALKHRLSRLIPVFSSFRKEVSEKRHEEFEKRRKAAEREFEAKKKQRVKEVQERRRREKIERENAERAKREEEERIKREEEERAARDAERRRILAEEKAKREEERAKMDEIAAKQRQREEEAEARLRAKRAGLSEPPRTESEVRTAPRLNIAPRTSGGPSWRERQAAKEAAGGAAPEAPKAEPEPPRRTGGYVPPHARGGSDAAPPAGNRYVPPSQRSSQPPSRTQTPPTSSPKPEEPKPLASGTGGKWVPRWKQQQQNQ
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit homolog, eIF3 p110, Translation initiation factor eIF3, p110 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYRIB_MOUSE
Sequence: MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPADEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAALRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIRSMLQ
What is the function of this protein?
Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling (PubMed:31285585).  Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions.  Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE-induced actin polymerization (By similarity).  Protects against Salmonella bacterial infection.  Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE-mediated bacterial entry (PubMed:31285585).  Restricts also infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes (PubMed:31285585).  Involved in the regulation of mitochondrial dynamics and oxidative stress (PubMed:29059164).
What are the official names of this protein?
CYFIP-related Rac1 interactor B, Protein FAM49B.
What is the protein family that this protein belongs to?
Belongs to the CYRI family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Mitochondrion.
Protein: RS21_LACP7
Sequence: MSNVIVKENESLDSALRRFKRNCAKAGIQQEIRKREHYEKPSVKRKKKSEAARKRKFK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PARP4_HUMAN
Sequence: MVMGIFANCIFCLKVKYLPQQQKKKLQTDIKENGGKFSFSLNPQCTHIILDNADVLSQYQLNSIQKNHVHIANPDFIWKSIREKRLLDVKNYDPYKPLDITPPPDQKASSSEVKTEGLCPDSATEEEDTVELTEFGMQNVEIPHLPQDFEVAKYNTLEKVGMEGGQEAVVVELQCSRDSRDCPFLISSHFLLDDGMETRRQFAIKKTSEDASEYFENYIEELKKQGFLLREHFTPEATQLASEQLQALLLEEVMNSSTLSQEVSDLVEMIWAEALGHLEHMLLKPVNRISLNDVSKAEGILLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEVNLGLLAKKADLCQLIRDMVNVCETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQIFRVGRVNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKVVEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVTTDFEDDEFVVYKTNQVKMKYIIKFSMPGDQIKDFHPSDHTELEEYRPEFSNFSKVEDYQLPDAKTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQDAPDVFTVSVGNLPPKAKVLIKITYITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTMSIEMPYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEKHPEKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIALHALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTMAAEFIMSATPTMGNTDFWKTLRYLSLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFLNDRLLVYGFIPHCTQATLCALIQEKEFRTMVSTTELQKTTGTMIHKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDENESPFPDIPKVSELIAKEDVDFLPYMSWQGEPQEAVRNQSLLASSEWPELRLSKRKHRKIPFSKRKMELSQPEVSEDFEEDGLGVLPAFTSNLERGGVEKLLDLSWTESCKPTATEPLFKKVSPWETSTSSFFPILAPAVGSYLPPTARAHSPASLSFASYRQVASFGSAAPPRQFDASQFSQGPVPGTCADWIPQSASCPTGPPQNPPSSPYCGIVFSGSSLSSAQSAPLQHPGGFTTRPSAGTFPELDSPQLHFSLPTDPDPIRGFGSYHPSASSPFHFQPSAASLTANLRLPMASALPEALCSQSRTTPVDLCLLEESVGSLEGSRCPVFAFQSSDTESDELSEVLQDSCFLQIKCDTKDDSILCFLEVKEEDEIVCIQHWQDAVPWTELLSLQTEDGFWKLTPELGLILNLNTNGLHSFLKQKGIQSLGVKGRECLLDLIATMLVLQFIRTRLEKEGIVFKSLMKMDDASISRNIPWAFEAIKQASEWVRRTEGQYPSICPRLELGNDWDSATKQLLGLQPISTVSPLHRVLHYSQG
What is the function of this protein?
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
What are the official names of this protein?
Protein mono-ADP-ribosyltransferase PARP4, 193 kDa vault protein, ADP-ribosyltransferase diphtheria toxin-like 4, ARTD4, PARP-related/IalphaI-related H5/proline-rich, PH5P, Poly [ADP-ribose] polymerase 4, PARP-4, Vault poly(ADP-ribose) polymerase, VPARP.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
Protein: RL23_PSYWF
Sequence: MNNARLYQVLKGPVFSEKSQLLGDSLGVQVFKVDNNATKREIKKAVELMFEGVEVTKVNTLNVKGKTKRFGRTVGRRNDYKKAYVTLKAGQDVQMADAGEEIADNAASTSETANNE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CYSG_PSYWF
Sequence: MNTFPLFFKLTNQPVLIVGGGEVAQRKADLLSRAGACITILAPQISQEIHQLLSDERHTLITAHYDKKYIDGKRIVIAGTDDEALNHQVHADCKALNIPVNVVDTPPLCDFIFPAIVDRNPIVIGISSNGKAPVLARLTRARLETLIPQGYGKLAKLAGDMRDEVKSKIPTLTGRRQFWEKAFEGKVSELMFAGRSVEAEQALKQQLEQTHQQLSSNSDVKQADPKSVGEVYIVGAGPGDPELLTFKALRLMQQADIVYYDALVSREVLDLCRRDADKVFVGKKRSNHAVAQQGINQLMIDAASSGKRVVRLKGGDPFVFGRGGEEIQALRAAGIAYQVVPGITAAGAASCYTGIPLTHRDYAQSVRFVTGFLKSGEPNTGFAALTNPNETVIFYMGLHSLERLTKGLMDAGRSPQTPIAIISQASMPTQQVMTGTLADIVAKHEANPLPTPALLIVGEVAKLHDELAWYGEHIVNTDQQAHALNML
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: TSAM2_COMTE
Sequence: MLVKNTWYVAGMATDCSRKPLARTFLNEKVVLFRTHDGHAVALEDRCCHRLAPLSLGDVEDAGIRCRYHGMVFNASGACVEIPGQEQIPPGMCVRRFPLVERHGLLWIWMGDPARANPDDIVDELWNGAPEWRTDSGYIHYQANYQLIVDNLLDFTHLAWVHPTTLGTDSAASLKPVIERDTTGTGKLTITRWYLNDDMSNLHKGVAKFEGKADRWQIYQWSPPALLRMDTGSAPTGTGAPEGRRVPEAVQFRHTSIQTPETETTSHYWFCQARNFDLDDEALTEKIYQGVVVAFEEDRTMIEAQQKILSQVPDRPMVPIAADAGLNQGRWLLDRLLKAENGGTAP
What is the function of this protein?
Involved in the toluene-4-sulfonate degradation pathway.  Does not discriminate between the sulfonate and the carboxyl substituents and can also be involved in the p-toluenecarboxylate degradation pathway (By similarity).
What are the official names of this protein?
Putative toluene-4-sulfonate monooxygenase system iron-sulfur subunit TsaM2, Toluenesulfonate methyl-monooxygenase oxygenase component TsaM2.