PharMolix/UniProtQA huggingface dataset:
Protein: TAT_HV1W2
Sequence: PTSQPRGDPTGPKE
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Tat seems to inhibit the HAT activity of KAT5/Tip60 and TAF1, and consequently modify the expression of specific cellular genes.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines (such as IL10) or cytokine receptors.  May be involved in the derepression of host interleukin IL2 expression.  Mediates the activation of cyclin-dependent kinases and dysregulation of microtubule network.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Host extracellular matrix metalloproteinase MMP1 cleaves Tat and decreases Tat's mediated neurotoxicity.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.  Binds to KDR/VEGFR-2.  All these Tat-mediated effects enhance angiogenesis in Kaposi's sarcoma lesions (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type (By similarity).
Protein: DAPB_CLOBB
Sequence: MIKIVLNGCCGKMGKVITECASKFNDLQIVAGIDKFPYETSYPIFETPEDLNLDYDVLLDFSRAGALKGLLNLTEKTKKPLVICSTGFSDEDLALIEEKSKTLPLFRSANMSLGINLINSLLRKVTPLLYGNYDIEIIEKHHNQKVDSPSGTAVLLADTIKESINDETKFVYGRSGASKREENEIGIHAIRGGSIVGDHDVIFAGVGEVIELSHKAISREVFAIGALKACEYMGNISIPGLYTMDDVIGITK
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_SALCH
Sequence: MSDNDQLQQIAHLRREYTKGGLRRRDLPAEPLTLFERWLGQACDARLADPTAMVVATVDDKGQPYQRIVLLKHYDEKGLVFYTNLGSRKAHQIEHNPRISLLFPWHMLERQVMVTGKAERLSTLEVVRYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSIEQMEFWQGGEHRLHDRFLYQRDDGAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: HUTH_ANASK
Sequence: METLLLDGETLTLEQVRAVATGAARAALAPAARERVRRSRALVDARLEDGEAHYGINTGFGTLAEVRIPRADLERLQRNLVLSHAAGVGAPLPLPEARALVLLRANVLAKGVSGIRERTLDLLLAMLERGVVPVVPERGSVGASGDLAPLAHLALVLIGDGEAFLAPPGAAGRPERLPGGEALRRAGLEPVVLQPKEGLALVNGTQAMAAVGTLALLRAERLAALADLAGAMTLEGLLGSHRPFAPEIQAARGQPGQIAAAAHLRALLAGSELNASHQGPGCHKVQDPYSLRCMPQVHGAARDGIGFCRGVLAREVNAATDNPLVFPDTGEIVSGGNFHGQPVALALDVLAVAASHLAAISERRVEQLVNPSLSGLPPFLAPQHGLNSGFMIAQVTSAALVSENKVLCHPASVDSIPSSAGREDHVSMGMTAALKARQVVENVRTCLAIELLVAAQALDLRAPLRPAQRVAEAHARLRERVPHLSEDRALHRDIEAVSSLVDEGGLEL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_PSEPK
Sequence: MGNLRVDVITLFPEMFSAITEYGITSRAVKQGLLQVTCWNPRDYTTDRHHTVDDRPFGGGPGMVMKIKPLEDALVSARQATGAAAKVIYLSPQGRKLTQQAVKGLAEQESLILIAGRYEGIDERFIEAHVDEEWSIGDYVLSGGELPAMVLIDAVTRLLPGALGHVDSAEEDSFTDGLLDCPHYTRPEVYADQRVPDVLLSGNHAHIRRWRMKQSLGRTFERRADLLESRSLSGEEKKLLEEYLRERDDS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_BRUSU
Sequence: MALDIKICGLKTPEAVAAALDGGATHIGFIFFPKSPRHITPDAAARLRAAATGRAVAVAVTVDADDEALDEIVKTVRPDMLQLHGGETPERVRFLKERYNLPVMKAFSIREAGDLEAIAPYRGIADRFLFDAKPPKGSELPGGNGISFDWNLLAALDADIDYMLSGGLNADNIAEALLKTGAPGIDISSGVECAPGEKDVRLIENFFQAVADANAQPFARRA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: HTF_BLACR
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, BlaCr-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATB_NATPD
Sequence: MTAQTAEEHSLTAVIGLEVHVQLETDTKIFCGCSTDADDNEEPNTRTCPVCLGLPGALPVLNEGAVEAAVKVGKALSSDIPEETRFHRKNYYYPDLPKNFQITQYDAPICDGGELEFAVDDERRTVAIERAHLEEDPGSLSHAGGSIDTAEHTLVDYNRAGTPLLEIVTAPDFRSAAEVRAFLAKLTEVLEYLGVFDVTRDGSLRVDANLSIVDSDAVGENGSIDEATLEAANRTEVKNISSHKGAEKALAYEETRQKNAVQRGREVEQETRHWDESRGITVSMRSKEEEKDYRYFREADIPPLRVSDWKEKIDIPELPDARRERFREEYGLDAETASKLTSTKQVADFYERVADTFAPELAATWVADNLLGELNYRDMEITDIEGRLDEFAHLIELVDEDEITVKNAEEVVLRRMLDDGQPPGDIVEAEDLGKTDDDAVAAAVTAAIEENPDAVEDYHAGEDGALNFLVGQVMQETGGSADPGTVNELLRAELDG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RL14_BACAA
Sequence: MIQQESRLKVADNSGARELLTIKVLGGSGRKYANIGDIIVATVKQATPGGVVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIKDDKSPRGTRIFGPVARELRDSNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL6_PSEF5
Sequence: MSRVAKNPVKLPAGVEVKFAGQQLSVKGAKGTLELNVHSSVEIVQEAGELRFAARNGDQQTRAMAGTTRALVNNMVQGVSQGFERKLQLVGVGYKAQAKGTVLNLALGFSHPVDYELPEGITAETPSQTDILIKGIDKQLVGQVAAEIRDFRPPEPYKGKGVRYADEVVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: NIRC_SALTY
Sequence: MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIILIFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTLGVKAGTISHGQMWAILPQTWLGNLVGSVFVALLYSWGGGSLLPVDTSIVHSVALAKTTAPATVLFFKGALCNWLVCLAIWMAIRTEGTAKFLAIWWCLLAFIASGYEHSVANMTLFALSWFGHHSDAYTLAGIGHNLLWVTLGNTLSGVVFMGLGYWYATPKSERPAPAKINQPEAAANN
What is the function of this protein?
Catalyzes nitrite uptake and nitrite export across the cytoplasmic membrane.
What are the official names of this protein?
Nitrite transporter NirC.
What is the protein family that this protein belongs to?
Belongs to the FNT transporter (TC 2.A.44) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_MYXXD
Sequence: MYAVIRTGGKQYRVAEGDVVRIEKIAGDVGAEVTFTEILLVGGSESPKVGQPTVAGAKVVGKVLAQDKHRRVLHFRKEKEGWTRRRGHRQPYTEVKVTSIAG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: LIX1_MOUSE
Sequence: MDRTLESLRHIIAQALPHRDPALVFKDLNVVSMLQEFWESKQQQKATFSSEGLVVYESMPSSGPPFVSYVTLPGGSCFGNFQCCLSRAEARRDAAKVALINSLFNELPSRRITKEFIMESVQEAVASTRGTLDDADDPSTSVGAYHYMLESNMGKTMLEFQELMTIFQLLHWNGSLKALRETKCSRQEVISYYSQYSLDEKMRSHMALDWIMKERESPGILSQELRAALGQLEEARKAGQELRFYKEKKEILSLALTQIYSDPDPSSPSDDQLSLTALCGYH
What are the official names of this protein?
Protein limb expression 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the LIX1 family.
Protein: DKSA_HAEIN
Sequence: MSRASLSLLDLAGVKPYQMKKDEEYMNEEQILHFRKILNAWHEQIVEEASRTVAHMQDEVTNFPDPADRATQEEEFSLELRNRDRERKLMKKIEATLKKLDTDDFGYCDCCGEEIGIRRLEARPTADLCIDCKTLAEIREKQVAG
What is the function of this protein?
Transcription factor that acts by binding directly to the RNA polymerase (RNAP).  Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.  Also required for regulation of fis expression.
What are the official names of this protein?
RNA polymerase-binding transcription factor DksA.
What is the protein family that this protein belongs to?
Belongs to the DksA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_SALTY
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMRELGMNAYLAVGHGSQNESLMSVIEYKGNPSEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMSNHNPLAHELIGASEQAGDRAWRLPLGDEFQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLSQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_ESCF3
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGATGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: EF2_CANAL
Sequence: MVAFTIEQIRGLMDKVTNVRNMSVIAHVDHGKSTLSDSLVQKAGIISAAKAGDARFMDTRKDEQERGITIKSTAISLYASMTDEDVKDIKQKTDGNSFLVNLIDSPGHVDFSSEVTAALRVTDGALVVVDTVEGVCVQTETVLRQALGERIKPVVVINKVDRALLELQTTKEDLYQTFARTVESVNVIISTYCDPVLGDVQVYPQKGTVAFASGLHGWAFTVRQFANKYSKKFGVDKEKMMERLWGDSYFNPKTKKWTNKDKDADGKPLERAFNMFILDPIFRLFAAIMNFKKDEIPVLLEKLEIQLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQAYRAETLYEGPSDDPFCTAIRNCDPNADLMLYVSKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYQVGKKEDLFLKSIQRTVLMMGRSVEQIDDCPAGNIIGLVGIDQFLLKSGTITTNEAAHNMKVMKFSVSPVVQVAVEVKNANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLENDHAGVPLRISPPVVSYRETVEGESSMVALSKSPNKHNRIYVKAQPIDEEVSLDIENGVINPRDDFKARARILADKHGWDVVDARKIWCFGPDGNGPNLVVDQTKAVQYLNEIKDSVVAAFQWATKEGPIFGENCRSVRVNILDVTLHADAIHRGGGQIIPTMRRVTYASMLLAEPAIQEPVFLVEIQCPENAIGGIYSVLNKKRGQVISEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQLIFDHWQVMSGDVTDENSKPGAIVKEKRVRAGLKPEVPEYTEYYDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBCD7_MOUSE
Sequence: MTDDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDIEKLCTFSQRFPLPSMYRALVWKALLGILPPHHDTHSQVMAYRKDQYHDILHALTVVRFISDATPQAEVYLRMYQLESGKLPRSPSFPLEPEDEVFLAIAKAMEEMVEDSVDCYWISRCFVKQLNNKYRDALPQLPKAFEQYLNLEDSRLLSHLKTCSAVSKLPYDLWFQRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSA
What is the function of this protein?
Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions.  The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB.  Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1.  It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
What are the official names of this protein?
TBC1 domain family member 7.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Note=Localizes in the cytoplasmic vesicles of the endomembrane in association with TSC1-TSC2 complex.
Protein: GATC1_CLOAB
Sequence: MSVSKKDVEYVAELARLSFSEEQKEGFMEDLNSILGYVDKLSELDTDNVDIIVNPYYIENKFREDEVEESMDLKDVIKNAPKNLEEYIVVPKIID
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C 1, Glu-ADT subunit C 1.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: COFH_METKA
Sequence: MRDSPDEVSVDELVNMAVAGGIDEGTALDALQGKLDPYKVMRAAHEARLKIVGEHVTFVVNRNINFTNVCINRCRFCAFRRDPDDPDAYRMTPEEVGERAAEARDAGATEVCLQGGLHPEATFEYYLEMLDEIKSQAPDIHVHGYSPMEVKYCAKLAGEDIEDVLRELKRAGLDSMPGTAAEIFSPEVRKRLCPDKLEADEWEHIIRIAHELGIPTTCTMMYGHIDSPRDWIDHMKRLRGIQEDTGGFTEFVPLSFVHSNAPIYRRGGARPGVSGMTDVLVHAVARLYFGPLIPNIQASWVKLGVKLAQMTLHAGANDLGGTLMEENISREAGATEGEQLEPEEIVEIIREAGFTPVQRTTLYEPVKVY
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: HEM6_POLNA
Sequence: MSSIDLSTVRTFLLGLQERITHAIAEVDGQPFMTDHWQKEPGETLQGNGITKILEQGRVFERAGCGFSHVRGPRLPPSATQHRPELAGAAFEAMGVSLVFHPRNPYVPTVHMNVRMLAATPVGENCEPVCWFGGGMDLTPFYGFDEDAVHFHQVCKDSLKPFGDDKYPRFKQWCDEYFYLKHRQEQRGIGGVFFDDFQELGLAQSFAMMQSVGDSFLQAYLPIVERRKDSLFGERERDFQLYRRGRYVEFNLVWDRGTHFGLQSGGRTESILMSMPPLASWSYQRPNEAGSPEERLYKEFLVRRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3086_DESHY
Sequence: MKLAIIGGYNFERHSKSMGKLKNIELRFHDGVPKKNNKKVLENLIKDTDCVIIVQMVCSHSSMWDAKDVARKYNKKIYYSQAKGLASVLTMIEKEHGIRTA
What are the official names of this protein?
UPF0751 protein DSY3086.
What is the protein family that this protein belongs to?
Belongs to the UPF0751 family.
Protein: MTAD_HALOH
Sequence: MKILIKNVDVIYTADSNRSIIKNGYIIIQDNKIKEINDMDNLVYQSNDFDDVISGKGKMALPGLVNAHTHSAMTLLRGFADDMPLHKWLQEKIWPFEKTLIPEDIYWGAKLAILEMIKTGTTTFADMYFEMGQVAKVVEEGGLRAVLSQGLIEANDGEEGLNRALKFCLEWNNRADGRILTMLAPHAPYTCSPDFFRRVVDLSQEYNLGIHTHIAETKEEFQQIREKYDCTPLQYLEKTGALKRPVLAAHCIYITEEDMDLMAQKPIGVAYNPQSNMKLGSGIAPVTRMLSKGIKVGIGTDGTSSNNNLDLIEEARSGSFLQKVNDLDSTALPVDTVLKMLTVNGAKILGFDKLGVLKEGYLADIILIGLNESTFYYPHYNNLSNLFYAGSGNDVTTVIVNGRVIMKDREVLTINEEEVYYKIEEIARRKL
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: FOLD_NITMU
Sequence: MSAKIIDGKRLSQEVRAECRARAARLAEKGTQPGLAVVIVGDNPASRVYVRNKAKACGETGIYSEVHEFPENANQDEVIGRIQELNGNPGIHGILVQLPLPRHFDSSRVTESVAVEKDVDGFHLYNVGALVTGSSIFPPCTPNGVMKMLEKYDIPIEGQHAVIVGRSNIVGKPMALMLLQKGATVTICTSRTRNLAEHTSRADILIVAAGKPRLITAMMVKPGATVIDVGINRLSDGKLAGDVDFESVKEKAGYITPVPGGVGPMTIAMLLCNTVVAAEQAHARLQGN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL11_BACC1
Sequence: MAKKVIKMVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTADQAGLIIPVEITVFEDRSFTFITKTPPAAVLLKKVAGIESGSGEPNRNKVATVKRDKVREIAETKMPDLNAASVEAAMRMVEGTARSMGIVIED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: YCK3_SCHPO
Sequence: MAATTGNIIKFEENADSKDLLEQCLNCSDVGVVSNTVRNMDGTIAADLARTLIPAMLINMQPSLAIWLHWIIVTHGGYLTTVMDLQDSLVQLHEKLVQSAHLMTKIFSLSGKLNMVLSQEEMRQRRLDFSSEDGEEEEENDYIDEDVDEAGYDIEVVDEAENDDMDNDLEANADAFDESNLEASLSPNAELSPRKSHIDHDFVIPEDEMLSEEEEQEVEKQILPKFVVPESPRKTSRKSR
What are the official names of this protein?
Uncharacterized protein C1450.03.
What is the protein family that this protein belongs to?
Belongs to the UTP5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CCME_WOLPP
Sequence: MKKKHKRLLITSGIFCFLSCAVFFILTTLKENISFFYTVSEAIVLPNNQKPIRVGGMIVENSVIRSESEVIFQMTDFNKSVMVKYQGILPPMFSEKSGVVVQGKMFDNGTFLADTVFAKHDENYKPKVLK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: CTA1_NIACI
Sequence: MVRFMYALRKRRLSLLLAMSLLVMCVASVVSPPPQALASGSGGIERVFTDKARYNPGDAVSIRVQAKNGTGSSWSGAARLEIFHLENSVYTSSQSLSLTNGQSTTLTFTWTAPSTDFRGYFVRIDAGTLGQGATAIDVSSDFTKYPRYGYISEFESGETALESKAKVDQLAQDYHINAWQFYDWMWRHDKMIKRTGGSIDSTWLDLFNREISWSTLQNQIDAVHDVNGKAMAYAMIYASRENYSPLGISPTWGIYEDSSHTNQFDVDFGDGSTYLYMSDPQNPNWQNYIHAEYIDSINTAGFDGIHVDQMGQRSNVYDYNGNSIDLSTRFSPFLDQAKSVLSANNPARDNLTYNIVDGTVNGWAVNDVSKNADLDFLYSEIWYLSDSYNQLKNYIEQLRANGGNKAVVLAAYMNYADNAGTRYEAESASMTNVSTNTNHAGYTGSGFVDQFASTGDKVSFAINAPEAGDYSLVFRYGNNTGANSTLNLYVDGNFVQKLYFFNQSSWGTWKHDAWYQVPLTQGAHTVELRYESGNVGAVNLDSLTLGTFDEHSVRLADAMMSASGATHIELGDDNQMLPHEYYPNRSKTMRSSLKNAMKDHYNFITAYENLLFDSDVVPNDTGSQFVNLTGVSASGDGSANTVWYINKRTSDYNIVHLINLLGNDNQWRNTASQPSFQTNLPAKIYIGADETISDVYLASPDLSGGETQELAFTSGTDAGGKYVSFTVPELKYWNMIYMKRTFSVPANDIYEAETAIKSNVSTNTNHAGYTGSGFVDGFSSTNDGVSFVVKSTASDDYALRFRYANGGSDATRDVYVDGKLAGTVSFKSTGSWSTWSYGEITARLEPGHHTIVLWQTSGNTGAINLDHLDLDKTYIWQFDRQIVSVPAGYRITFRTGLPGWVHWGVNGWTGVTDTPLRSNGSLDGNLDHETSIGPFATGTAVDVTFLWDDNNNGILEPSTDRWEGTDFGINVS
What is the function of this protein?
Produces cycloisomaltooligosaccharide from dextran containing 7, 8 or 9 glucose units.  The enzyme is specific for (1->6)-alpha-D-glucans (dextrans) and, without activity toward (1->4)-alpha-D-glucans, such as amylose.  It also has no activity on oligosaccharides, such as amylopectin and pullulan, containing (1->6)-alpha-D-glucosidic linkages at branch points.
What are the official names of this protein?
Cycloisomaltooligosaccharide glucanotransferase, CITase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 66 family.