PharMolix/UniProtQA huggingface dataset:
Protein: BIB11_SICTE
Sequence: GDSRRPIWNIAHMVNDLDLVDEYLDDGANSLELDVEFSKSGTALRTYHGVPCDCFRSCTRSEKFSKYLDYIRQLTTPGNSKFRSRLILLVLDLKLNPLSSSAAYNAGADVARNLLDNYWQRGDSKARAYIVLSLETIAGAEFITGFKDTMKKEGFDEKYYDKIGWDFSGNEDLGKIRDVLESHGIREHIWQGDGITNCLPRDDNRLKQAISRRYSPTYVYADKVYTWSIDKESSIENALRLGVDGVMTNYPARVISVLGEREFSGKLRLATYDDNPWEK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (PubMed:25752604).  This toxin acts on lysophosphatidylethanolamine (LPE) and ceramide phosphoethanolamine (CPE) with high activity (PubMed:25752604).  This toxin acts on sphingomyelin (SM) with very low activity and is not active on lysophosphatidylserine (LPS), lysophosphatidylcholine (LPC) and lysophosphatidylglycerol (LPG) (PubMed:25752604).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate as second products (PubMed:25752604).  It is not surprising that spider toxins have affinity for ethanolamine-containing sphingolipids since they are common in insect prey (PubMed:25752604).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin StSicTox-betaIB1i, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily. Class IIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YJDH_BACSU
Sequence: MYHYFYGPALIPYFSHTHNPQRSPDFSERQRRREITLTVDGFVPPSSTEDLGDGFYSYAWTNQQVINPGEYLVCHLEGRDINVINGGFTPRDTAPLYAVASFPRRRNQWVIIIHNPVQTQRAISLYLIAKR
What are the official names of this protein?
Uncharacterized protein YjdH.
Protein: CH10_CAMFF
Sequence: MKFEPLGKRVLVEREEEVKTTASGIIIPDNASKEKPSKGKVVAASKEAEGVSVGDIVVFAKYAGSEISLEDKKYLVLNLEDILGVIK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYCBP_PONAB
Sequence: MAHYKAADSKREQFRRYLEKSGVLDTLTKVLVALYEEPEKPNSALDFLKHHLGAATPENPEIELLRLELAEIKEKYEAIVEENKKLKAKLAQYEPPQEEKRAE
What is the function of this protein?
May control the transcriptional activity of MYC.  Stimulates the activation of E box-dependent transcription by MYC (By similarity).
What are the official names of this protein?
c-Myc-binding protein, Associate of Myc 1, AMY-1.
What is the protein family that this protein belongs to?
Belongs to the AMY1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates into the nucleus in the S phase of the cell cycle.
Protein: 3L255_OPHHA
Sequence: MKTLLLTLVVVTIVCLDLGYTTKCYVTPDVKSETCPAGQDICYTETWCDAWCTSRGKRVNLGCAATCPIVKPGVEIKCCSTDNCNPFPTRKRP
What is the function of this protein?
Binds to muscular and neuronal nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission (PubMed:35341214).  Pseudo-irreversibly inhibits twitches in chick biventer cervicis nerve-muscle preparations in a concentration-dependent manner (PubMed:35341214).
What are the official names of this protein?
Alpha-elapitoxin-Oh3a, CM-11, Long neurotoxin OH-55.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ZMAT5_DANRE
Sequence: MGKRYYCDYCDRSFQDNLHNRKKHLNGVQHHRAKKAWFDNFRDAATLLNDERSKEVCRKFVQTGQCVFGTSCRFSHMSEKQMKMLEQKIDDEKRQKEDPDQDGSSERSVDEWLSRREKKLAALTSGRVLRMEEEECTENIEIPPYLLSIPDLPPSLHPPPAGGWRVTVHNEWG
What are the official names of this protein?
Zinc finger matrin-type protein 5, U11/U12 small nuclear ribonucleoprotein 20 kDa protein, U11/U12 snRNP 20 kDa protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: G6PI_LEPIN
Sequence: MIRLETRFASSFIQSSKLEPFLEKSESARLTLHSSQGQGKEYLGWLYLPKELKNSEIERMTQVAERLRNSSEVIVVIGIGGSYLGSRAVLEATLPFFKKPSIGNPEIIFAGHHLESRYFSELIEYLEDKNFSINVISKSGTTTEPAIAFRLLWELLRKKYGSSASSRVVATTDSSKGVLKKFADSEKLDTFTIPDNVGGRYSVLTPVGLFPLAVAGISISKFILGFQNILNDIHSITDPTRNPATYYSALRNYFLSEGRYIEVLANFNPSLRYVSEWWKQLFGESEGKENKGIFPASMDFTTDLHSLGQYIQEGKRILFETVLSPSEVCSNLTLKPTQDNLDSLNFLSGNTLGYVNEQARLGTLLAHADGGVPCLELVFPDISPQSLGELMYFFEYSCAISGYSLGVNPFDQPGVEAYKKNMFALLNKPGFEQEGETLRKRISRN
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_CLOBH
Sequence: MKKAILGKKLGMTQIFNENGKVIPVTVIEAGPCTVIQKKTVEKDGYEAIQVAFGDIREKLRNKPIKGHFAKAGVSVKRHIKEFKLEDSNSLEIGQEIKADVFEAGERVDISGVSKGKGFQGTIRRWNAHRGPMSHGSKFHRAVGSMGASSDPSRTFKNKRMPGHMGNVNTTVLNLEVVRIIPEKNLILIKGGVPGPNKGLVQIRNTVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ZN507_PONAB
Sequence: MEESSSVAMLLPDIGEQEAILTAESIISPSLEIDEQRKTKPDPLIHVIQKLSKIVENEKSQKCPLIGKKRPHSSAATHSLETQELCEIPAKVTQSPAAVTRRAEMSQTNFTPDTLAQNEGKAMSYQCSLCKFLSSSFSVLKDHIKQHGQQNEVILMCSECHITSRSQEELEAHVVNDHDNDANIHTQSKAQQCVSPSSSLCRKTTERNETVPDIPVSVDNLQTHTVQTASVAEMGRRKWYAYEQYGMYRCLFCSYTCGQQRMLKTHAWKHAGEVDCSYPIFENENEPLGLLDSSAAAAPGGVDAVVIAIGDSELSIHNGPSVQVQICSSEQLSSSSPLEQSAERGVHLSQSVTLDPNEEEMLEVISDAEENLIPDSLLTSAQKIISSSPNKKGHVNVIVERLPSAEETLSQKRFLMNTEMEEGKDLSPTEAQIGREGTDDVYRADKCTVDIGGLIIGWSSSEKKDELMNKGLATDENAPPGRRRTNSESLRLHSLAAEALVTMPIRAAELTRANLGHYGDINLLGPDTSQRQVDSTLAAYSKMMSPLKNSSDGLTSLNQSNSTLVALPEGRQELSDGQVKTGISMSLLTVIEKLRERTDQNASDDDILKELQDNAQCQPNSDTSLSGNNVVEYIPNAERPYRCRLCHYTSGNKGYIKQHLRVHRQRQPYQCPICEHIADNSKDLESHMIHHCKTRIYQCKQCEESFHYKSQLRNHEREQHSLPDTLSIATSNEPRISSDTADGKCVQEGNKSSVQKQYRCDVCDYTSTTYVGVRNHRRIHNSDKPYRCSLCGYVCSHPPSLKSHMWKHASDQNYNYEQVNKAINDAISQSGRVLGKTPGKTQLKSSEDSADPITGSSENAVSSSELMSQTPSEVLGTNENEKLSPTSNTSYSLEKISSLAPPSMEYCVLLFCCCICGFESTSKENLLDHMKEHEGEIVNIILNKDHNTALNTN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 507.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGD_RHOCB
Sequence: MIASVLPTYTRAPLAFVRGEGSWLWTADGSRYLDLGAGIAVNALGHAAPDLVATLTEQAGKLWHVSNLYRIPEQERLADMLVAKTFADTVFFTNSGTEACELAVKMVRKHFYDKGQPERTEILTFSGAFHGRSSAAIAAAGTEKMVKGFGPLLPGFVHLPWGDLDAVKAAVTETTAAILIEPIQGEGGIRPAPEGFLRALREICDETGTLLVFDEVQCGVARTGKLFAHEWAGVTPDVMMVAKGIGGGFPLGAVLATEDAASGMIAGTHGSTYGGNPLGCAIGAKMIEIVTAPGFLDEVSRKAGFLRQWLEGLVAAHPDIFEEVRGQGLMLGLRLKLPPGDVVKAAYAQNLLTVPAADNVLRLLPALTISEDDMAEAVRRLDAAAASLETQPA
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR3_TOBAC
Sequence: MGQKINPLGFRLGTTQGHHSLWFSQPKNYSEGLQEDQKIRDCIKNYVQKNMRTSSGVEGIARIEIQKRIDLIQVIIFMGFPKLLIESRPRGIEELQTTLQKEFHCVNRKLNIAVTRIAKPYGNPNILAEFIAGQLKNRVSFRKAMKKAIELTEQADTKGIQIQIAGRIDGKEIARVEWIREGRVPLQTIRAKIDYCSYTVRTIYGVLGIKIWIFLDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DUT_ALBFT
Sequence: MIKIDVKIIDPRMADQLPAYATPGSAGLDLRACLDAPLTLLPNAWQLVPTGIAIYLKDPKFAAMILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSAWNRSDVAFTIEPMERIAQLVIVPVLQAQFNVVSEFPASARGEGGYGSTGKG
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: YIDE_ECO57
Sequence: MSDIALTVSILALVAVVGLFIGNVKFRGIGLGIGGVLFGGIIVGHFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVIIGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMEMVDQMGMSYAMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESSRTNGGALIKTINIRVENPNLHDLAIKDVPILNGDKIICSRLKREETLKVPSPDTIIQLGDLLHLVGQPADLHNAQLVIGQEVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASGDISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVPGFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKSGGDFVNTLVNGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPPALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG
What are the official names of this protein?
Putative transport protein YidE.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y874_METJA
Sequence: MMLLLAILHKNDADYFIAEAMGVKIIEEEAYKKISKETFEEALKELKNSDVVVYTDFPIGEMNELNLKLIEEAKNLKKRMIFYEDDISVLKEI
What are the official names of this protein?
Uncharacterized protein MJ0874.
What is the protein family that this protein belongs to?
To B.subtilis YdcN C-terminal region.
Protein: RNPH_YERPA
Sequence: MRPADRAAQQVRPLTLTRNYTKHAEGSVLVEFGDTKVLCTATVEEGVPRFLKGQGQGWITAEYGMLPRSTHSRNAREAAKGKQGGRTLEIQRLIARSLRAAVDLKKLGEFTITLDCDVLQADGGTRTASISGACVALADALNKLVASGKLKANPMKGLVAAVSVGIVKGEALCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHEELLALLDLARGGIETIFQAQKAALES
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: TTCA_ECOSM
Sequence: MSQNQEISKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLETLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGDLAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM9_VANPO
Sequence: MLMSKAPKLGNLLSKNSIKIVSGSKLRCNLKYINVRYISDTPDKVFTKLSDENDPQRDAFFKYSWGSWMKNDAIEKEKRVTKFSIEGLNDVLNDIYEQTKVEAKVTKEGAIKPPSFNKNLTVSLPHNLTVKNIGVINPNEKVQITSMASIHEGKHHRIYKIDTNLGKSFVLRVPYALENEDTIAQRLKSEVASMDFADLKLGIKVPKTYCFGINGLNPIRQPFILQEYIDGKLLMRDWSPLENDTSDGKPPVALQDVINKLSEFQSKLISMKFNGFGSIYFAKDAEELENVPELYDNETNEELKGRWKLGYSVERCLWKKKSFLPTDKLKTFLGPWSINKPTDIIRATGLLEAENAKVRLGLKEADSSSEAVESGVLKSQVATFENLVKLAPSLINSETKSIPNISDLLLPRLKHPDLDPMNVLVTENNEVYLLDFEGSSIKPLILQNAPQFVAYDGPKVYNIEKEVPDYEKLSDSEKAQYEFMYKRTRNQFLWEMAFNKTNPEFISIVAPPVKLLRSPYIAAIERKTDEEYILVDEAMIQLKEIWDIFTKNGLVKNSPYPIEYTTEQLEQHGKDLLKFHEKLISQPFAATQGWIPQDMFENLVAGGVLVKNKSGDYEVSSEAQSEVQSEVQSSTENKD
What are the official names of this protein?
Altered inheritance of mitochondria protein 9, mitochondrial, Found in mitochondrial proteome protein 29.
What is the protein family that this protein belongs to?
Belongs to the AIM9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FAD6C_BRANA
Sequence: MASRIADSLFAFTGPQQCLPRAPKLASARLSPGVYAVRPIDLLLKGTRRTFLVPAKKRIGCIKAVFVPVAPPSADNAEDREQLAESYGFKQIGQDLPDNVTLKDIMDTLPKEVFEIDDVKAWKSVLISVTSYALGLFMIAKAPWYLLPLAWAWTGTAVTGFFVIGHDCAHKSFSKNKLVEDIVGTLAFLPLVYPYEPWRFKHDRHHAKTNMLVHDTAWQPVPPEEFDSSPVLRKAIIFGYGPIRPWLSIAHWVNWHFNLRKFRPSEVNRVKISLACVFAFMAVGWPLIIYKVGVLGWVKFWLMPWLGYHFWMSTFTMVHHTAPHIPFKPADEWNAAQAQLNGTVHCDYPSWIEILCHDINVHIPHHISPRIPSYNLRAAHQSIQENWGKYTNLATWNWRLMKTIMTVCHVYDKEENYIPFDRLAPEESQPITFLKKAMPDYAA
What is the function of this protein?
Chloroplast omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes.  It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol.
What are the official names of this protein?
Omega-6 fatty acid desaturase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Peripheral membrane protein.
Protein: PSD_CLOBA
Sequence: MIKVYNRITKEYEEENVAGKKFIKWTYETPVGKSITELIAKRKIFSKFYGKFCDTKRSAKKIPDFVENFNIDMNIAEKNISDFNSFNDFFVRNLIPTSRPIDTNENILISPGDGRITVYDNIDLDNIVQIKGLTYSLRELIKNDQITENYKDGICIILRLCPTDYHRFHFVDSGIPCETHKIKGHYYSVNPIALNSIPKLFCENKREWNIFKSENFGDILTVEVGATCVGSIIQTYEPNKRVLKGAEKGYFKFGGSTTILFLEKDKVKIDNDILEQSKQGYECKVLFGETIGTKIL
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PDXH_YERPE
Sequence: MTENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATVDTNGQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLESKFLELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: XYLA_STRVO
Sequence: MSFQPTPEDKFTFGLWTVGWQGRDPFGDATRPALDPVETVQRLAELGAYGVTFHDDDLIPFGSSDTERESHIKRFRQALDATGMTVPMATTNLFTHPVFKDGGFTANDRDVRRYALRKTIRNIDLAAELGAKTYVAWGGREGAESGGAKDVRDALDRMKEAFDLLGEYVTAQGYDLRFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQSGIKYDQDLRFGAGDLRAAFWLVDLLESAGYEGPRHFDFKPPRTEDFDGVWASAEGCMRNYLILKERAAAFRADPEVQEALRAARLDQLAQPTAADGLEALLADRTAFEDFDVEAAAARAAWPFERLDQLAMDHLLGARG
What is the function of this protein?
Involved in D-xylose catabolism.
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_COXB1
Sequence: MSGGVKLIAGLGNPGDQYARTRHNVGAWFLETLAQQRNQSLAKENKFHGFVAKCNDYWLLKPTTFMNESGQAVAALARFYKIKPSEILIAHDELDFPAGDIRLKEGGGHGGHNGLRNIIQHLGSSDFYRLRIGINHPGYKDRVTPYVLSPPSENDRIAILAAIEKGLRLIPELVQGDFQKVMRELHS
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y020_PROMP
Sequence: MAGFGLPNFGQLTEAFKKAKEIQQNAQKLQDELESMEIEGKSDDEMIKVWISGNQLPLRVEVNENISTANKEEIEKNILEAIKKAHESSTTTMKERMNDLTGGLNLNLPGLDNNDS
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein PMM0020.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PSD_FUSNN
Sequence: MNFEKIQYIERKTGEIKTEKVMGEGALKFLYYNPFGKLALHAVVKRKFLSDWYGRKMSKPESKEKIKSFVEEMEIDMSEYKRPIEDYASFNDFFYRELKDGARKIDYNENVIVSPADGKILAYQNIKEVDKFFVKGSKFTLEEFFNDKELAKKYEDGTFVIVRLAPADYHRFHFPVDGEISEIKKILGYYYSVSTHAIKTNFRIFCENKREYAILKTEKFGDIAMFDIGATMVGGIVQTYKTNSSVKKGEEKGYFLFGGSTCILVFEKNKVVIDKDIIENTQNKIETRIYMGEKFGNEKN
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DEOC_GEOTN
Sequence: MTVNIAKMIDHTLLKPEATEEQIIQLCDEAKQHGFASVCVNPAWVKTAARELSDTDVRVCTVIGFPLGATTPETKAFETNNAIENGAREVDMVINIGALKSGNDELVERDIRAVVEAASGKALVKVIIETALLTDEEKVRACQLAVKAGADYVKTSTGFSGGGATVEDVALMRRTVGDKAGVKASGGVRDRKTAEAMIEAGATRIGTSSGVAIVSGQTGGADY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_CALS8
Sequence: MKAVYIIGTDTDVGKTLICAGLCWALKEKGYNIGYFKPVLSGAKRRGKMLIPQDTEFVVNFAKIKGDIYRLTPFIFEKPASPHIAASDENVDINVNQIKQTFEDLSQNYEFVIIEGCGGLAVPLKEERNQFYMQYQLIKEICNNVILVTTTKLGTINHTLLTVEFAKAYGLCLKGIIVNMYKNEPDEDKVINTITKFTNIPILAKVDFINDFPSDVDENKFKNVFKKCFDDRAIRKIMGVFEC
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_ECO81
Sequence: MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICKREDPRDAFVSNTYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ARGB_SHEB8
Sequence: MSTNNSVLVLKVGGALLQCEMGMARLMDTAAAMLANGQQVLMVHGGGCLVDEQLAANGMETVKLEGLRVTPPEQMPIIAGALAGTSNKILQGAATKAGIVSVGMSLADGNTVSAKIKDERLGLVGEVTPKDGAYLKFILAQGWMPICSSIAMMDDGQMLNVNADQAATALAKLVGGKLVLLSDVSGVLDGKGQLIHSLNGKQIADLVKQGVIEKGMKVKVEAALEVAQWMGQAVQVASWRDASQLIALAKGEAVGTQIQP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL416_YEAST
Sequence: MKHVKPFFLFVDPKKSASGKQGEASSHGKGFLICRYASFPLHTESKVVRFANVTDQKFGHALSFFFSYIHCTRHVGSAPLTVSQPHIDVHCEQPISFHVSQCPAYENCHSLPLDPQSPLHSPPLSTSPDSRR
What are the official names of this protein?
Putative uncharacterized protein YLR416C.
Protein: BLAC_BACUN
Sequence: MKAYFIAILTLFTCIATVVRAQQMSELENRIDSLLNGKKATVGIAVWTDKGDMLRYNDHVHFPLLSVFKFHVALAVLDKMDKQSISLDSIVSIKASQMPPNTYSPLRKKFPDQDFTITLRELMQYSISQSDNNACDILIEYAGGIKHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKELKDFLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADGMKTADNDAGLVILPDGRKYYIAAFVMDSYETDEDNANIIARISRMVYDAMR
What are the official names of this protein?
Beta-lactamase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: AROQ_BORA1
Sequence: MARSILVLHGPNLNLLGTREPEVYGSRTLAQINEDLSSLANELGVSLSAWQSNHEGALVDRIQAASKDGTDFIIINAAAYTHTSVALRDALAGVAIPFIEVHLSNLYKRESFRHHSYLSDIAVGLISGLGADGYEAALRYAVRH
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RAP2A_PIG
Sequence: MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSACVIL
What is the function of this protein?
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.  In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK.  Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development.  More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading (By similarity).
What are the official names of this protein?
Ras-related protein Rap-2a.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Midbody. Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Note=Localizes to midbody at telophase. May also localize to the Golgi and the gelatinase-containing granules of neutrophils.