PharMolix/UniProtQA huggingface dataset:
Protein: RLMH_ERYLH
Sequence: MLLHIIARGKIARSPEEELVTRYEKRLTWPVKLTELPETGGRIPDPQTPFKTVLLDERGKDLSSHRLARQLERWRDDGMRETRFVLGAADGHAQEERAEADLLLAFGSATWPHLLARAMLMEQLYRATSILAGHPYHRAG
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRO_ADE04
Sequence: MAAGSGEQELRAIIRDLGCGPYFLGTFDKRFPGFMAPHKVACAIVNTAGRETGGEHWLAFAWNPRSNTCYLFDPFGFSDQRLKQIYQFEYEGLLRRSALATKDRCVTWKSHQTCRVRVGRCGFSAACSTACAWPTPMDKNPTMNLLTGVPNGMLQSPQVEPTLRRNQEALYRFLNSHSAYFRSHRARIEKATAFDRMNQDM
What is the function of this protein?
Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions.  Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors.  Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating.  Without maturation, the particle lacks infectivity and is unable to uncoat.  Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.  Cleaves host cell cytoskeletal keratins K7 and K18.
What are the official names of this protein?
Protease, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C5 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Present in about 10 copies per virion.
Protein: HIS8_HALMA
Sequence: MEPRDLSAHTVYRAGRGIEEVARELGLDPDDMVKLASNENMFGPSPDAVEAIRGSAERMHSYPKASHADLVDELADMWDVTPEQVWLSNGGDGALDCLARAMLDPGQDVLVPSPGFAYYAMSARYHHGEVNEYTLSKADDFAQTADTVLKDYDGERIVYLTSPHNPTGAEFTTDAVRTIAEETDEQTLVVVDEAYGEFTEKPSKRPLLSDRDDVALLRTFSKAYGLAGIRLGYAVVPEDWADAYARINTPFSASELACRAGLAALDDDEHVERSVDTAAWAREYLSAELDAPTWDSAGNFILAEVGDASAIADAAQERGVIIRDCSSFGLPECIRITCGTREDTERAVSVLNEVIEEVKA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RUVA_MARMM
Sequence: MIGMLTGRVAALGADELVLDVSGVGYLVGAGARTLSRLEPDQDIVLHIETHVREDAFKLYGFLDDIDRAWFVHLQNIQGVGAKAAFAILDTVPVSEIANAAALGDKSTFARAKGVGPKLATRIATELKDKAPPTGRSFSIGLPVHSDDGTTGGAPVAPAGGDSLAREDAVSALVNLGYNESQARQAVAKILRDADSEAPLGDVIRLSLKELAA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: APT_BACP2
Sequence: MDLKQYVTVVPDYPKEGVQFKDITTLMDKGEVYRYATDQIVEYAKERDIDLIVGPEARGFIIGCPVAYALGVGFAPVRKEGKLPREVVKVEYGLEYGKDVLTIHKDAIRPGQRVLITDDLLATGGTIEASIKLVEELGGVVAGIAFLIELTYLDGRKKLDGYDILTLMQY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_MESFL
Sequence: MAYKEVTRDELSAAGVQYGHQTKRWNPKMAPFIYGSKSKNHVIDLEKTLIQLRQAEKLVQSIGAKGEKVLFVGTRRSAKLAVKEAALRSGNYYVNQRWLGGTLTNFKTIVKRIKALWEIEESEKNGQLALRTKKEQILILKEKANLEKSLGGIKQMRKLPAALIVVDPKSDEIAVKEAIKLNIPVIGLCDTNVDPDIVTLPIPANDDLQESVNIMINALVDAFADGANLKLAPSVLKTVVVKRERTEGENNYSNNRSWNKPERTNN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NUOI_ECO57
Sequence: MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKDKGEAENEAKPIDVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I, NUO9.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLMN_AERHH
Sequence: MSETKTNLLDLDRDAMRAFFVELGEKPFRADQVMKWIYHFGCDDFDQMNNVNKVLRERLKAIAEIRAPEVSREQRSSDGTIKWALQVGGQEVETVYIPEEDRATLCVSSQVGCALECKFCSTAQQGFNRNLKVSEIIGQVWRAAKIVGGKRPITNVVMMGMGEPLLNLANVVPAMRLMMDDFGYGISKRRVTISTSGVVPALDMLGDQIDVALAISLHAPNDKLRSEIMPINDKYNIEEFLAGVRRYLGKSNANGGRVTVEYVLLDHINDDMQHAHELAKVLKDTPSKINLIPFNPFPGNPYGKPSNSRIDRFSKVLMEYGFTVIVRKTRGDDIDAACGQLVGEVIDRTKRTMKNRMQQDGISVKMV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOS6_HUMAN
Sequence: MPGDHRRIRGPEESQPPQLYAADEEEAPGTRDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGGGPAGAGGEAPAALRGRLLCDFRRAPFAGRRRRAPPGGCEERELALALQEALEPAVRLGRYPRAQLEVSALLLEDGGSALAAALTAAALALADAGVEMYDLVVGCGLSLAPGPAPTWLLDPTRLEEERAAAGLTVALMPVLNQVAGLLGSGEGGLTESWAEAVRLGLEGCQRLYPVLQQSLVRAARRRGAAAQP
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
What are the official names of this protein?
Exosome complex component MTR3, Exosome component 6, mRNA transport regulator 3 homolog, hMtr3, p11.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: GSDMC_HUMAN
Sequence: MPSMLERISKNLVKEIGSKDLTPVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVEFSLNDILEPSSSVLETVVTGPFHFSDIMIQKHKADMGVNVGIEVSVSGEASVDHGCSLEFQIVTIPSPNLEDFQKRKLLDPEPSFLKECRRRGDNLYVVTEAVELINNTVLYDSSSVNILGKIALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRKQLVIKEKAILISDDDEQRTFQDEYEISEMVGYCAARSEGLLPSFHTISPTLFNASSNDMKLKPELFLTQQFLSGHLPKYEQVHILPVGRIEEPFWQNFKHLQEEVFQKIKTLAQLSKDVQDVMFYSILAMLRDRGALQDLMNMLELDSSGHLDGPGGAILKKLQQDSNHAWFNPKDPILYLLEAIMVLSDFQHDLLACSMEKRILLQQQELVRSILEPNFRYPWSIPFTLKPELLAPLQSEGLAITYGLLEECGLRMELDNPRSTWDVEAKMPLSALYGTLSLLQQLAEA
What is the function of this protein?
Pore-forming protein that causes membrane permeabilization and pyroptosis (PubMed:27281216).  Released upon cleavage and binds to membrane inner leaflet lipids.  Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis (By similarity).  The functional mechanisms and physiological proteases that cleave and activate this pore-forming protein are unknown (Probable).
What are the official names of this protein?
Gasdermin-C, Melanoma-derived leucine zipper-containing extranuclear factor.
What is the protein family that this protein belongs to?
Belongs to the gasdermin family.
Protein: NADK_STAS1
Sequence: MRYTILSKGDSKSNALKHKMINHMKDFQMVEDPDNPEIVISVGGDGTLLQAFHQYSYMLSRCAFVGIHTGHLGFYADWLPHEVEKLIIEINNSEFQVIEYPLLEIIVRYNDNGYETRHLALNEATMKTENGSTLVVDVNIRGNQFERFRGDGLCISTPSGSTAYNKALGGALIHPSLEAMQIAEIASINNRVFRTVGSPLVLPKHHTCLITPVNQDTILTTIDHVSIKHKNVNAIQYRVANEKIRFARFRPFPFWKRVHDSFISSGDDE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIB2_ARATH
Sequence: MDQSSSTLLINQRKSSSSPTRIPPKQKRKSTTTHKPIKVRYISNPMRVETCPSKFRELVQELTGQDAADLPPSPTTFTAVDLHRPCESEMNLEPLDGEVRGEYYSPLDEEVFNAPQMSAGLSGFFSSGFYNVNALGSIGSL
What is the function of this protein?
Functions as activator of WRKY33 in plant defense against necrotrophic pathogens by stimulating the DNA-binding activity of WRKY33.
What are the official names of this protein?
Sigma factor binding protein 2, chloroplastic, Sigma factor binding protein II, VQ motif-containing protein 16, AtVQ16.
What are the subcellular locations of this protein?
Plastid, chloroplast. Nucleus. Note=Can localize to both chloroplast and nucleus.
Protein: RPIA_CRYNB
Sequence: MPSPAVDLLKQKTASLPNAPISVVAANTFVPPTQPVTAGNQLPTSVPLPVLPAVEAAKRLAAYAAVDRHIAHEHKVIGIGSGSTVPYVVDRILAQGFEANKDRVFLPTGFQSKELIVKAGLTLGDVDQYARIDVTIDGADEVDNELNSIKGGGACQLREKVLAEAADTWIIVADYRKNSEVLGTSWTKGIPIEVVPFAYAKVLTNLAHMGSPHVLPNGQPGLSLRMGKMKAGPVVSDNGNFIIDAPFAEELMRQPEELLHKIKMLTGVVEVGLFCGMAKAAYFGNEDGSVTIRSDDGTISQL
What are the official names of this protein?
Ribose-5-phosphate isomerase, D-ribose-5-phosphate ketol-isomerase, Phosphoriboisomerase.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COATR_MYCTU
Sequence: MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQPSDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAENDLTLEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEHNAVFLARP
What is the function of this protein?
Probably involved in fatty acid metabolism.  Binds to fatty acyl-CoAs of varying carbon chain lengths, with the highest binding affinity for palmitoyl-CoA (C16:0).  In vitro, alters the cell wall lipid profile and protects mycobacteria from acidic, oxidative and antibiotic stress.  May play a significant role in host-pathogen interaction.
What are the official names of this protein?
Probable fatty acyl-CoA transferase Rv3272.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family.
Protein: YCEJ_BACSU
Sequence: MNRIWLFFSVMFVIGTDTFLLSPLLPLLQDQFHVSTDLSGWMVSAYALGYALFAFIAGPISDRLNRKTVMLWGLAGFIVSTFLCGIAPSFAAMCLFRFAAGVSAAFVTPQIWASIPVIVQPSQIIKGMGIATAGLAASQMLGLPIGGFLASFTWHTPFFVLSACSLILLLILAAVMPGIRPSEPLARPSIVNPYRELFSLPKTSVILLAYFLFQTGNFASFSFLGTWLSADYHLTVSQIGAAMLVLGLGNMLGSLIGSRVSEKLGMFKTLISGMLLMGALYFALPFFPNLFLVEAGFFLTFFTAGIIFPLMMGVFQSIAPNARGTIASLSNAAMYAGTTVGTSIAGFLYQSTQHFGAVTGFTAILFILSMTLYQTISKTGKRQSTARAQL
What are the official names of this protein?
Uncharacterized MFS-type transporter YceJ.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RT19_PETHY
Sequence: MPRRSIWKGSFVDAFLLRMKKKRDLLFNRKIWSRRSSILPEFVDCFVRIYNGKTFVRCKITEGKVGHKFGEFAFTRKRRPSRTNIGPGRKRGKK
What are the official names of this protein?
Ribosomal protein S19, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RECO_RHOPS
Sequence: MEWSDEGIILGVRRHGEAGAIVELLTRSHGRHLGLVRGGASSRMRPLLQPGNSVLAVWRARLDEHLGYYQLEGTRMRAATMLASSHAVYGVTHLASLARLLPERDPHEDIYEMLERTLDDFDDVGDAATHLIRFELAMLAELGFGLDLSACAATGATVELIYVSPKSGSAVSRAAGEPWRDKLLRLPAFLRDDNDGRNGWSDQDLRDGFDLTGRFLLRNVLEPRGQGHSDARDGFINAVTRHLARTAIP
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: UCHL_DROME
Sequence: MLTWTPLESNPEVLTKYIHKLGVSPAWSVTDVIGLEDDTLEWIPRPVKAFILLFPCSETYEKHRAEEHDRIKEVEEQHPEDLFYMRQFTHNACGTVALIHSVANNKEVDIDRGVLKDFLEKTASLSPEERGRALEKDEKFTADHEALAQEGQTNAANHEKVIHHFIALVNKEGTLYELDGRKSFPIKHGPTSEETFVKDAAKVCKEFMARDPNEVRFTVLALTAAQQ
What is the function of this protein?
Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins.  This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase, Ubiquitin thioesterase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family.
Protein: XKR8_HUMAN
Sequence: MPWSSRGALLRDLVLGVLGTAAFLLDLGTDLWAAVQYALGGRYLWAALVLALLGLASVALQLFSWLWLRADPAGLHGSQPPRRCLALLHLLQLGYLYRCVQELRQGLLVWQQEEPSEFDLAYADFLALDISMLRLFETFLETAPQLTLVLAIMLQSGRAEYYQWVGICTSFLGISWALLDYHRALRTCLPSKPLLGLGSSVIYFLWNLLLLWPRVLAVALFSALFPSYVALHFLGLWLVLLLWVWLQGTDFMPDPSSEWLYRVTVATILYFSWFNVAEGRTRGRAIIHFAFLLSDSILLVATWVTHSSWLPSGIPLQLWLPVGCGCFFLGLALRLVYYHWLHPSCCWKPDPDQVDGARSLLSPEGYQLPQNRRMTHLAQKFFPKAKDEAASPVKG
What is the function of this protein?
(Microbial infection) Incorporated into Ebola virus-like particles, where its phospholipid scramblase activity is required to promote phosphatidylserine exposure on the surface of viral particles (PubMed:29338048).  Externalization of phosphatidylserine on the surface of viral particles is required for uptake by host cells (PubMed:29338048).
What are the official names of this protein?
XK-related protein 8, hXkr8.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region.
Protein: DBP6_YEAS7
Sequence: MFASRFDPSQLTAPAASAPEGIVGTTPPAIVPLKRQATESDNEEYGSHQDSDESSNSSSEEDEDRMQVDYGASEEDSSEVEEEESKPSTHSTVLSRFKQTVSLQERLGASDIAESKEDESIEDEAASTHQLKQIPQPEFVKNPMNLNTNSLQFKSTGWLNTEKIYYDNSLIKPFSDYANELEAKLLQNICKNFSTNTFPIQSIILDSILPVLNFTLNVSKRNFTRRIGDILVNAATGSGKTLAYSIPIVQTLFKRQINRLRCIIIVPTKLLINQVYTTLTKLTQGTSLIVSIAKLENSLKDEHKKLSNLEPDILITTPGRLVDHLNMKSINLKNLKFLIIDEADRLLNQSFQGWCPKLMSHLKTDKLDTLPGNVIKMIFSATLTTNTEKLNGLNLYKPKLFLKQTDKLYQLPNKLNEFNINIPTAKSIYKPLILLYSICQFMAHSPIAAKILIFVKSNESSIRLSKLLQLICESRSQSSVLKNLQNLAVSINSVNSNNSKAENKKIVANFSHPSESAGITILITTDIMSRGIDINDITQVINYDPPMSSQQYVHRVGRTARANELGSAYNLLVGRGERTFFDDLNKDLDRDGKSVQPLELDFTLLESDSELYTSSLESLKNYHNNTAQA
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP6, DEAD box protein 6.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YQGF_STRT2
Sequence: MRVMGLDVGSKTVGVAISDPLGFTAQGVEIIKINEEAKEFGFDRLGELVKEYQVDKFVVGLPKNMNNTEGPRVEASKAYGDKIKEIFNLPVDYQDERLTTVQAERMLVEQADVSRGKRKKVIDKLAAQLILQNYLDRMF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_LEGPH
Sequence: MIIHNLGIKDYTEIWEQMKEFTAIRDSNSYDELWLLEHYPVYTQGQAGKPEHVLNPNSIKIVQSDRGGQVTYHGPGQLVAYVLMDIRRRNLGIRTLVAKLEEILISVLEHYRIPANIRSGAPGVYVGEKKIASIGLRVKNGCTYHGIALNVNMDLSPFLGINPCGFAKMEMTQMSHFHPNIQLEEVSQHLVQYFLTQFK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIND_MESVI
Sequence: MIEQINKDGEKKNSTDTRTIVITSGKGGVGKTTTTANLGMSIARLGYKVALIDADVGLRNLDLLLGLENRVIYTAMEVFEGECCLDQALIRDKRWSNLALLAISKTRQRYHLTRRNMEMLVDSIRLRNYNFILIDCPAGIDVGFVNAVAPAEEAVVVTTPEITSIRDADRVAGLLEASGIYEVKLLVNRVRPDMIQKNDMLSVRDVQEMLGIPLLGAIPEDTNVIVSTNRGQPLVLNKKLTLSGISFENAARRLVGRKEYLVNLETGNKGLLKRVQQFLTGSEENV
What is the function of this protein?
ATPase required for the correct placement of the division site.
What are the official names of this protein?
Putative septum site-determining protein MinD.
What is the protein family that this protein belongs to?
Belongs to the ParA family. MinD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRC_DROME
Sequence: MMSSRTQDADGASIRFSDHTLDKATKAKVTLENYYSNLVTQYGERKQRLAKLEAQLKDESLSEAQRQEKRLQHAQKETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVEVRSIDDTSNFDEFPDVSLEIPSAPIPQGGEIAKDWVFINYTYKRFEVRNLE
What is the function of this protein?
Serine/threonine-protein kinase involved in controlling cell structure and proliferation of a variety of polarized outgrowths including epidermal hairs, bristles, arista laterals, and dendrites (PubMed:11102376, PubMed:15479641, PubMed:32022690).  Together with fry, maintains the integrity of epidermal hairs and is an essential component of the signaling pathway regulating dendritic branching of sensory neurons (PubMed:15479641).  Reduces neurite outgrowth by phosphorylating pav, thereby inhibiting its function in microtubule-microtubule sliding (PubMed:32022690).
What are the official names of this protein?
Serine/threonine-protein kinase tricornered, NDR protein kinase, Serine/threonine-protein kinase 38-like, Serine/threonine-protein kinase tricorner.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Trc colocalizes with Mob1 to the cell periphery in wing cells and wing hairs.
Protein: ISPD_LYSSC
Sequence: MQYEVVLPAAGSGKRMGAGQNKLFLKLLKKPILIHTLEVFQQDPFCTGIWLAVKPEERIYIQELLDEYRITKVKGLPNGGAERQHSVHSCMKEMEQVDIVLVHDAARPFITHAIIANLVQSAHDFGAAIAGVRAKDTMKKVRNGVIEETVDRDSLWMIQTPQAFRFDLIVEAEDVAEKVGFLGTDEAMLVERLGHTVHIVESSYENVKMTTQEDLLFGEAILRKRALQLNE
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: CSRA_VIBCH
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYMRIQAEKGNGGVASGNY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_COXBR
Sequence: MARINQLVRKPRRARAKKSDVPALEGCPQRRGVCTRVYTITPKKPNSALRKVARVRITNGAEVTAYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGSLDTAGVSGRRRGRSKYGEKKPKE
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.