PharMolix/UniProtQA huggingface dataset:
Protein: Y666_HAEIN
Sequence: MRDLVRSGKVFLYGEFIGLLREDHRGFHFSYNPDYQGIPLSLSFPIEQSPFHSDTLFPYFASLVPEGWLKHKYALHQRIDESDMFRFLLNNGENMLGAVQIQEEKQ
What are the official names of this protein?
Uncharacterized protein HI_0666.
Protein: HIS1_SULTO
Sequence: MKMAIPNKGRLKDPVVQFLASVGVKGNFSDDRALIIPTNWEGVQLVMVRTEDIPSIVESGAAELGITGHDYVIESNSDVDELIRLDFGKSKIVLAVPVSWNIDRVEEIKDEIRIATKYYNIAKQYLEKKNIKAKIVKISGAAEVMPSLGAADAIIDVMSTGTTLKLHGLKPLDTILESSAVVIANRNWVKSEEADKINLLLTMMKGALMARNKKMIFMNVPDDKLDKVIASLPAMLSPTLSKLAKSDAWEVITVVDEDLIPEVIAKVKANGARDIVVVNIEKVVK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_HELPY
Sequence: MKIGVYGASGRIGKLLLEELKGGYKGLALSSVFVRQKCETDFSSFSHAPLVTNDLKAFVRACECVIDFSLPKGVDNLLEALLECPKILVSGTTGLEKETLEKMQQLALKAPLLHAHNMSIGIMMLNQLAFLTSLKLKDADIEIIETHHNLKKDIPSGTALSLYETCAKARGYDEKNALITHREGLRSKESIGIAALRGGDVAGKHTIGFYLEGEYIELSHTATNRSIFAKGALEVALWLKDKAAKKYEINEMFG
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPHB_SYNY3
Sequence: MPLSSQPAILIIGGAEDKVHGREILQTFWSRSGGNDAIIGIIPSASREPLLIGERYQTIFSDMGVKELKVLDIRDRAQGDDSGYRLFVEQCTGIFMTGGDQLRLCGLLADTPLMDRIRQRVHNGEISLAGTSAGAAVMGHHMIAGGSSGEWPNRALVDMAVGLGIVPEIVVDQHFHNRNRMARLLSAISTHPELLGLGIDEDTCAMFERDGSVKVIGQGTVSFVDARDMSYTNAALVGANAPLSLHNLRLNILVHGEVYHQVKQRAFPRVT
What is the function of this protein?
Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.
What are the official names of this protein?
Cyanophycinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
Protein: GLN1B_MYCBO
Sequence: MTEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV
What is the function of this protein?
Involved in nitrogen metabolism via ammonium assimilation (PubMed:24112767).  Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia (PubMed:24112767).  Also plays a key role in controlling the ammonia levels within infected host cells and so contributes to the pathogens capacity to inhibit phagosome acidification and phagosome-lysosome fusion (By similarity).  Involved in cell wall biosynthesis via the production of the major component poly-L-glutamine (PLG) (PubMed:24112767).  PLG synthesis in the cell wall occurs only in nitrogen limiting conditions and on the contrary high nitrogen conditions inhibit PLG synthesis (PubMed:24112767).
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I beta, GSI beta.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOOT1_MEDTR
Sequence: MSLEDSLRSLSLDYLNLLINGQAFSDVVFSVEGRLVHAHRCILAARSLFFRKFFCGPDPPSGLDPSGNRVNPSGSARSGVIPVNSVGYEVFLLMLQFLYSGQVSIVPQKHEPRPNCGDRGCWHTHCTSAVDLALDTLAAARYFGVEQLALLTQKQLASMVEKASIEDVMKVLLASRKQDMHQLWTTCSHLVAKSGLPPEVLAKHLPIDIIAKIEELRIKTSLSRRSLMPHHHHPHHHDHLTAAADLEDQKIRRMRRALDSSDVELVKLMVMGEGLNLDEALALPYAVENCSREVVKALLELGAADVNFPAGPTGKTPLHIAAEMVSPDMVAVLLDHHADPNVRTVDGVTPLDILRTLTSDFLFKGAVPGLTHIEPNKLRLCLELVQSAALVMSREEGNNNNSNNNNNATASSATNMYPHHNMNEDHHHSHNNNNMDSRLVYLNLGANTQMSTSRMDSGDDDNTHREAINNSMYHHHSHGHDY
What is the function of this protein?
Involved in the promotion of leaf and floral meristem fate and determinacy (PubMed:23136374).  Promotes normal stipule growth and development (PubMed:23136374).  Involved in the coordination of the symbiotic nodule developmental program (PubMed:23136374).  Necessary for the robust maintenance of nodule identity throughout the nodule developmental program (PubMed:23136374).  Involved in the regulation of indeterminate nodule identity in association with NOOT2 (PubMed:30026291).
What are the official names of this protein?
BTB/POZ domain and ankyrin repeat-containing protein NOOT1, Protein NODULE ROOT 1, MtNOOT1.
Protein: ESR1_OREAU
Sequence: MYPEESRGSGGVATVDFLEGLMTMTAPTPAPTPLYSHSTTGCYSAPLDAHGPLSDGSLQSLGSGPTSPLVFVPSSPRLSPFMHPPSHHYLETTSTPVYRSSHQPVPREDQCGTRDEAYSVGELGAGAGGFEITKNTRFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGMRKDRGRVLRREKHGPAQRQTSQNLPTHKASPQDGRKRAMSSSSTSGPGGRSSLNNMPPDQVLLLLQGAEPPILCSRQKMSRPYTEVTIMTLLTSMADKELVHMITWAKKLPGFLQLSLHDQVLLLESSWLEVLMIGLIWRSIQCPGKLIFEEDLILDRNEGTCVEGMAEIFDMLLATVRFRVLKLKPEEFVCLKAIILLNSGAFSFCTGTMEPLHDSVAVQHMLDTITDALIFHISHFGCSAQQQSRRQAQLLLLLSHIRHMSNKGMEHLYSMKCKNKVPLYDLLLEMLDAHRIHRPVKPSQSWSQGDRDSPTASSTSSRGGGGGDDEGASSAGSSSGPQGSHESPRRENLSRAPKGPGVLQYRGSHSDCTRIP
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
What are the official names of this protein?
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUV3_SACPA
Sequence: MTLVKYSTIAFPLRSFRLFIFVKKALYHNEPHSIDPFHDKNWIVKRPKFLNLPKNEHSKLDVFQFNFNKSKSNNVYLRDPLFRDNLDKAMQIIYNEKLSSLDAKQVPIKNLAWLKLRDSIYQQLEDPKQQTKNYVPSISEIIYPSSPGNLISLLINCNKIGNSVWKSILKNGQSNNISTLDKFIHVLQQTFDHMYEQEILPMMTNTDDTDGAHNVDITNPAEWFSEARKIRRHIIMHIGPTNSGKTYRALQKLKSVDRGYYAGPLRLLAREVYDRFQSEKVRCNLLTGEEVIRDLDDKGNPAGLTSGTVEMVPINQKFDVVVLDEIQMMSDADRGWAWTNALLGVVSKEVHLVGEKSVLPLVKSIVKMTGDKLTINEYERLGKLSVEDKPVKDGIKGLRKGDCVVAFSKKKVLDLKLKIEKDTNLKVAVIYGSLPPETRVQQAALFNNGEYDIMVASDAIGMGLNLSIDRVVFTTNMKYNGEELMEMTSSQIKQIGGRAGRFKSKSTSGGVPQGFITSFESKVLKSVRKAIESPIEYLKTAVTWPTDEICAQLMTQFPPGTPTSDLLQTISDELERSSDNLFTLSDLKSKLKVIGLFEHMEDIPFFDKLKLSNAPVKDMPMVTKAFTKFCETIAKRHTRGLLSYRLPFNLLDYNCIPNESYSLEVYESLYNIITLYFWLSNRYPNYFIDMESAKDLKYFCEMIIFEKLDRLKKNPYAHKPFGSTRGQFPSSRGRLRT
What is the function of this protein?
Probable ATP-dependent RNA helicase involved in a variety of mitochondrial post-transcriptional processes and in translation.  It is a key control element in nuclear-mitochondrial interactions.
What are the official names of this protein?
ATP-dependent RNA helicase SUV3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LSRK_YERPP
Sequence: MSQLDTTTPSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLTTNWQLTCQCIRQALHLAKLPASAIRAVAACSMREGIVLYDRSGTPIWACANVDARASREVSELKELHNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPDIYRQAGTLTMISDWLANMLSGELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAKAAQECGLLAGTPVVMGGGDVQLGCLGLGVVHAGQTAVLGGTFWQQVVNLPQPIIDPNMNTRINPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMPIFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEENAAIVSACNLAQIAEFSGVKASSVVFAGGGAKGKLWSQILADVTGVPVKVPVVKEATALGCAIAAGVGVGLYEALDKTGERLVRWEREYIPNTEHKALYQAAKTNWQAVYTDQLGLVDCGLTTSLWKAPGL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HERC6_MOUSE
Sequence: MYFSWAAGSRKPRRLKAGTSGIELLQAASGEHHSLLLFSNHRVYSCGDNSWGQLGQRRDQSTERPEPIQALNDLHVDLVSCGKEHSVAVCHKGKVFAWGAGSEGQLGIGEFKEISFMPTKIKALAGIKIIQVSCGHYHSLALSEDGHVFSWGRNSEGQLGLGKNSRSQAIPQKVKSLEGIPLAQVAAGGTHSFALSLTGTSFGWGSNRSGQLALSGNKVKEQIYKPHSIGALKNLSVIYISCGYEHTAVLTEEGQVFTFGGNSSGQLQPSPRSGQRGPQLIEGIGGRVSQIECASYHTIAYVYTTGQVVSLGRGPSHTSNPTHQEAPAENSDITCLLAAEDLVDIEVKDIFAGAHANFVTTRRVSHTRSTGVSMKILPEIIRINQSLVKKWRAANKRKDREGAKREISLIFSSSACLTASFLKKRDAGENNLIDVDLKLARDVFKKLTTEKWISSLITTCLEEYLLRDLPYSSPHQEALLVFLLLPECSIMQDPKNWKTLAFEFAKAIHKMGPQSLAFLRTCWASLEVSSLNILVQMLKKAIISQIQYGVATEQYITNIKVLLEVIKEVHKANCQLPESAFIINELSGIFNFDAEAGRMFIRHNDLDCTESSDMVVFSDFLFVFDLPSKIKLMKCDSFVKLMSEVMAFPEKMSSPPYLILKVRRSHLVEDTLRQLRQVEDFDLRKQLSVGFINEIRPEAGGVSSEFFHCIFEEMTDPKYEMFIYPEKGSSMWFPVNPKFEKSSYFLFGILCGLSLHNLKVINLPFPLALYKKLLNQKPSLEDLKELSLPLGRNLQEVLNCEAGDIEELHMYFSIYWDQKDVDLIPDGISVPVNETNKRDYVSKYVDYIFNISIKTIYEEFHRGFYKVCNWDIIRQFQPEELMTAIIGNATCDWKQFENNSKYKDGYDKSHPTILLFWKAFHDLTLDEKKKFLLFLTGCDRLHVKGLQNEGIVFRCSETFSEEDNPRSLTCHRMLDLPKYSSMRRMKEALQVAINNSTGFVSQE
What is the function of this protein?
Major E3 ligase for ISG15 conjugation.  Acts as a positive regulator of innate antiviral response in cells induced by interferon.
What are the official names of this protein?
E3 ISG15--protein ligase Herc6.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Exclusively cytoplasmic.
Protein: SYA_DELAS
Sequence: MSTPTFTVADIRKSFLDFFASKGHTIVESSPLVPGNDPTLMFTNSGMVQFKDVFLGTDKRPYKRATSVQTCLRAGGKHNDLENVGYTARHHTFFEMLGNWSFGDYFKRESLKWAWELLTEVYKLPKERLLATVYAEDDEAYDIWTKEIGLPPERVIRIGDNKGGRYKSDNFWMMADTGPCGPCSEIFYDHGAHVAGGPPGSPDEDGDRFIEIWNNVFMQFDMDEQGNVKPLPAPCVDTGMGLERLAAILQHVHSNYEIDLFQALIKAAARETHIADIETPSLKVIADHIRATAFLVADGVIPSNEGRGYVQRRIVRRAIRHGYKLGQKTPFFHKLVKDLVAVMGDAYPKIREQEARITEVLRVEEERFFETLANGMEILDAALAGGAKVLPGDVAFKLHDTYGFPLDLTNDVCRERGLSVDEAGFQTAMEEQKNKARAAGKFKMDRALEYTGDANAFTGYQKLAEAAKVVALYAEGSAVQELKAGQSGVVVLDTTPFYAESGGQVGDQGVISTAGARFAVEDTLKIKADVFGHHGVLESGSLKVGDAVQAEVDTQLRAATMRNHSVTHIMHKALREVLGDHVQQKGSLVNAERTRFDFAHNQPVTAEEIREIERRVNAEILANTPTDARVMDIESAKATGAMMLFGEKYGDSVRVLDIGSSRELCGGTHVQRTGDIGLFKVVGEGGVAAGVRRIEAVTGENALAYLQSLESTVDQAAAALKAPTAELNTRIGGALEQIRALEKEVAALKGKLASSQGDELAGQAVDVKGIKVLAARLEGADAKTLRDTMDKLKDKLGAAAIVLAAVDGDKVQLAAGVTKAETSRIKAGDLVNFVASQVGGKGGGKPDMAMAGGTDASGLPAALAGVHAWVAERV
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP_PHV
Sequence: MSKFCLCLSLLGVLLLQVCDTRSLLELKIECPHTVGLGQGLVIGTVDLNPVPVESVSTLKLESSCNFDVHTSSATQQAVTKWTWEKKADTAETAKAASTTFQSKSTELNLRGLCVIPTLVLETANKLRKTVTCYDLSCNQTACIPTVYLIAPIHTCVTTKSCLLGLGTQRIQVTYEKTYCVSGQLVEGTCFNPIHTMALSQPSHTYDIVTIPVRCFFIAKKTNDDTLKIEKQFETILEKSGCTAANIKGYYVCFLGATSEPIFVPTMDDFRASQILSDMAISPHGEDHDSALSSVSTFRIAGKLSGKAPSTESSDTVQGVAFSGHPLYTSLSVLASKEDPVYIWSPGIIPERNHTVCDKKTLPLTWTGYLPLPGGIEKTTQCTIFCTLAGPGADCEAYSDTGIFNISSPTCLINRVQRFRGAEQQIKFVCQRVDLDIVVYCNGMKKVILTKTLVIGQCIYTFTSVFSLMPGIAHSLAVELCVPGIHGWSTIALLATFCFGWLLIPIISLVSIKIMLLFAYMCSKYSNDSKFRLLIEKVKQEYQKTMGSMVCEVCQQECEMAKELESHKKSCPNGMCPYCMNPTESTESALQAHFKVCKLTTRFQENLRKSLNPYEPKRGCYRTLSVFRYRSRCFVGLVWCILLVLELVIWAASADTVEIKTGWTDTAHGAGVIPLKSDLELDFSLPSSATYIYRRDLQNPANEQERIPFHFQLQRQVIHAEIQNLGHWMDGTFNLKTSFHCYGACEKYAYPWQTAKCFLEKDYEFETGWGCNPGDCPGVGTGCTACGVYLDKLRSVGKVFKVISLKFTRRVCIQLGSEQSCKTIDSNDCLMTTSVKVCMIGTVSKFQPGDTLLFLGPLEEGGIIFKQWCTTTCHFGDPGDIMSTPQGMQCPEHTGAFRKKCAFATMPTCEYDGNTLSGYQRMLATRDSFQSFNITEPHITSNSLEWVDPDSSLKDHINLVVNRDVSFQDLSENPCQVGVAVSSIDGAWGSGVGFNLVCSVSLTECASFLTSIKACDAAMCYGATTANLVRGQNTVHILGKGGHSGSKFMCCHSTECSSTGLTAAAPHLDRVTGYNVIDNDKVFDDGSPECGVHCWFKKSGEWLMGILSGNWMVVAVLVVLLILSIFLFSLCCPRRVVHKKSS
What is the function of this protein?
Forms homotetramers with glycoprotein N at the surface of the virion.  Attaches the virion to host cell receptors including integrin ITGAV/ITGB3.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis.  Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion.
What are the official names of this protein?
Envelopment polyprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the hantavirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein N]: Virion membrane; Multi-pass membrane protein. Host cell surface. Host Golgi apparatus membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host mitochondrion. Note=Interaction between glycoprotein N and glycoprotein C is essential for proper targeting of glycoprotein N to the host Golgi complex, where virion budding occurs. SUBCELLULAR LOCATION: [Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host cell surface. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Budding probably takes place at the host Golgi (Probable). Glycoprotein C cytoplasmic tail is important for efficient Golgi localization (By similarity).
Protein: CYC6_LIMMA
Sequence: GDVAAGASVFSANCAACHMGGRNVIVANKTLSKSDLAKYLKGFDDDAVAAVAYQVTNGKNAMPGFNGRLSPKQIEDVAAYVVDQAEKGW
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.
Protein: PDXH_RHIL3
Sequence: MSANELTSGDFTESGEPFKLFAEWLKEAEVSEPNDPNAVALATVDEDGLPNVRMVLLKGFDDDGFVFYTNFESQKGREILGQKKAAMCFHWKSLRRQVRLRGPVEIVTDAEADAYFKTRARGSRIGAWASRQSRPLESRFALEKAVAEYTARYAIGEIPRPAHWSGFRIRPTSIEFWKDQKFRLHDRVEFRRPSPEGEWDKVRMYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RL24_COXB1
Sequence: MAIKKIKKDDTVIVITGRDKGRQGKVLKVLPNSRLLVEGINLVKKHVKPNPNKNEQGGILERELSIHVSNVAIYNPAAKKADRVGIKTLEDGSKVRIFKSNGEVIDV
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: VHED_XANCP
Sequence: MKVQIMSSAVAVRSFPAREGKPATHFREQTAAVLREGDFPLPFTIGLDEDQPPYGEGFYIIDPKSLQNNKFGGLEFGRRIRLIPDLTAKLQQQPAKVG
What is the function of this protein?
Single-strand DNA-binding protein required for DNA replication.
What are the official names of this protein?
Phi-Lf prophage-derived helix-destabilizing protein, Single-stranded DNA-binding protein, SBP.
Protein: SIPL3_ORYSJ
Sequence: MAFPAPSSSSPRRRGRGLAYLLVSVLLLASRVPGAAGADSEFEDGVSPKFPGCDNPFQKVKVTYWVDGDERSSLTGITARFGEVLPATGSDGDKRKAVVPAPKTGCAKSSAPLASSIAVAERGECTFLEKAKTAESGGAAALLLINDEDDLQKMVCTQNDTVPNIGIPVVMVSQSAGRKILSGMDGGAKVDILMYAPEKPSFDGAIPFLWLMAVGSVACASVWSFVVVGDEDKNAPTLGGEEAADSEIVELQTKTALVFIVTASLVLLFLFFFKSTWSAWLLVVLFCLSGLQGLHYVASTLIVRTCDRCREAKVALPVLGNVTVVTLVILPLALIFVVVWAVHQNSPFAWVGQDLMGICMMILVLQVVHLPNIKVATALLVSAFMYDIFWVFISPFIFKKSVMITVARGSDEGPSLPMVLKMPKEFDTWNGYDMIGFGDILFPGLLVAFSFRYDRANGKDLTDGYFLCLMIGYAFGLSCTYVGLYLMKSGQPALLYLVPSTLGTIVTLGAKRGELSQLWNAKV
What is the function of this protein?
Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.
What are the official names of this protein?
Signal peptide peptidase-like 3, OsSPPL3.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22B family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: RL13_BRUA1
Sequence: MATFSQKPAEVVKKWVLIDAEGLVVGRLASLVANRLRGKHKATFTPHVDDGDNVIIINADKVVLTGKKYTDKKYYWHTGHPGGIKERTARQILEGRFPERVLEKAIERMIPRGPLGRRQMKNLRVNAGPNHQHEAQQPEVLDVAALNRKNKGNA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: METAA_OCEIH
Sequence: MPIKIPIHLPAKDILEKENIFVMDDQRAITQDIRPLNILILNLMPEKQKTETQLLRFLGNTPLQVHISFLRMSSHESKHTSKYHLDTFYKKFEEVKSKKFDGMIITGSPVEHLPFEEVDYWKELQDIMNWSKENVTSTLHICWGAQAALYHHYGIDKHHLPQKCFGVYEHKLLHPHERLVRGFDDYFFAPHSRYTDVSISEIEAHPDLQLLAKSDDAGVFLLASKDGKHIMATGHLEYSAETLAEEYLRDHQRGVDTAIPENYFPDNDPKKQPKYRWKSHCSLLFSNWLNYYVYQETPYQWGE
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_ACIB3
Sequence: MSQLSTIIEQAFEDRANFTAADCPSEIRQAVEEAIAGLDNGTLRVAEKINGEWVVHQWLKKAVLLSFKLNDNKPIESCDLRFYDKVETKFSGWTEEQFKAAGVRVVPPAVARRGSFQAKNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVPGNLPSADGKYSLYAAIIVKKVDAQTRAKTSLNDLLRAD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_BACVZ
Sequence: MNTETRRVTDKRERPLRDLRISVTDRCNFRCTYCMPAELFGPDYPFLQKTELLSFEELERLAKLFVGRFGVEKIRLTGGEPLMRKDMPELIKKLARIPGLKDIAMTTNGSLLPVYAEKLKQAGLHRVTVSLDSLEDERFKAINGRGVSVNKVLEGIEAAKAAGLGVKINMVVQKGVNEKDILPMARYFKEKGHILRFIEFMDVGNTNQWNKKDVITKAEIIDLINQHMPTEPIEANYKGEVASRFRYLDGSGEIGVISSVSDAFCASCNRARLSARGELFTCLFASSGYDVRKLVRGGLTDDELTESIASVWRNRTDQYSIDRALSKTDGKKKVEMSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: SYT_LISIN
Sequence: MKITFPDGAVKEFEPGVSTADIAASISPGLKKKALAGKLNGELLDLVTPIHEDGAIEIVTPDHEDALGILRHSTAHLMAQALKRLYPDVKFGVGPAIESGFYYDIDTEAVISDESLVEIEKEMQKIVRENVPIEREVVSREEAIKRFEAIGDQYKLELIEAIPEDETVTIYTQGEFFDLCRGVHVPSTGKIQVFKLLSVAGAYWRGDSNNKMLQRIYGTAFFDKNGLKEFIQMQKEAKERDHRKLGKELDLFANSIEVGQGLPLWLPKGATIRRVIERYIVDKEERLGYNHVYTPIMANVELYKTSGHWDHYHEDMFPTMKMDNEELVLRPMNCPHHMMIYKNDIHSYRELPIRIAELGMMHRYEMSGALSGLQRVRGMTLNDAHVFVRPDQIKDEFKRVVELILEVYKDFDIKDYSFRLSYRDPKNTEKYFDDDAMWEKAQAMLKSAMDEMNMDYFEAEGEAAFYGPKLDVQVKTAIGKEETLSTVQLDFLLPERFDLTYIGEDGEKHRPVVIHRGVVSTMERFVAYLIEEYKGAFPTWLAPVQMELIPVNADAHLDYAKGVQDKLQRAGLRAEVDDRNEKLGYKIREAQTKKIPYALVLGDQEVEAGSVNVRRYGSKDSETMDLDAFIAQVVAEVSKY
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_MESM1
Sequence: MIILDGKKLSQKDTIFLKEKVNQFKIKPVFTIVQVGNLFSSNKYIKTKMDKALEIGVVSRLIKIPESISEKDLISIIEEESKISHGLIVQLPLPLQFDQSKILNSVPITKDIDGLSEKNSKNLYSGKSCIQPATARGIIDLIKEYNFTIKDKKVYVIGESNLVGKPIKELFKQAGAIVKSFNINTGIKGSEEADILIVAAGHPNLVKPENVKNNSIVIDVGINSIGENDKMIVTGDVDFSNVKTKVKAISPVPGGVGPMTVISLFKNLIEIFEKYLLDDN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: LL1_LASLA
Sequence: VNWKKVLGKIIKVAK
What is the function of this protein?
Antimicrobial peptide which assumes an amphiphilic alpha-helix conformation upon contact with membranes (PubMed:19591185).  Insertion into membranes involves Trp-3 (By similarity).  Penetrates into cells once membrane has been permeated (By similarity).  Active against Gram-negative bacteria (E. coli (MIC=1. 7 uM) and P. aeruginosa (MIC=15. 8 uM)) and Gram-positive bacteria (S. aureus (MIC=14. 3 uM) and B. subtilis (MIC=0. 8 uM)) (PubMed:19591185).  Has cytotoxic but no hemolytic activity (PubMed:19591185).  Binds DNA in vitro (By similarity).  In the context of inflammation and cancer tests, a 3-residues C-terminally truncated lasioglossin-1 is weakly cytotoxic to normal cells, induces calcium signaling but does not impact cAMP production (PubMed:36548715).  In addition, this truncated peptide prevents LPS-induced nitric oxid (NO) synthesis but does not affect the IP3 signaling and pro-inflammatory activation of endothelial cells (PubMed:36548715).  This truncated peptide does not show significant antiproliferative activity on the breast cancer cell line MDA-MB-231 (PubMed:36548715).
What are the official names of this protein?
Lasioglossin-1, LL-I.
What is the protein family that this protein belongs to?
Belongs to the lasioglossin-like family.
What are the subcellular locations of this protein?
Secreted.