PharMolix/UniProtQA huggingface dataset:
Protein: POXB_PENO1
Sequence: MSEAEPSVVVAEQCRRSACDRCRGQKLRCERPVSNSSTTPCRRCLKAHVRCVTTAQPHRTKPLSSLQYLHHTESNYDPHSATVAGQLPVAAVAGLGDLDPSLLHMTGVQNPRRLSHSSSMANPVDSRPPGRTRRLSNPDHFLPHPPLHPNGVLDTDGTPLLDSIDHLPDMTASRGFGFSAALTPHSPSGSSDFFDYFRPMAEDNNRSPWMDAFTNLPPDHREGTPAGSNYRGSLTGENQFRSSLQSSRGLNGFETPQRESRHREMDIVSIKNECIARMGKLNRGLLQDVGLVNSGKVAGTLLFSQASRSTYLEVEKGRKGGQNYVIGKMLHSSKELLDILKQLERCKSTLFPPGHTERTTSTADEVTTAMTETTTLNQTGSHAPSSPLGGNPLPPLSGPLSASASHSSSCASSSSASASTSGASLLSSSTSAPSTSPAISLQLDTTLTLLFLTGYTSVIQLYEGVFSFIRDSVAANPSGSNFLPTLPKLQVDGFEVGSSTRDLQICILLQVSTHILNQIEERLHAIRDRAEGHVPAALLDTILDRSDPSQRGAKGRELCRIVRDIKEHLKHYAE
What is the function of this protein?
Transcription factor that positively regulates the expression of the gene cluster that mediates the biosynthesis of oxaleimides, cytotoxic compounds containing an unusual disubstituted succinimide moiety.
What are the official names of this protein?
C6 finger transcription factor poxB, Oxaleimides biosynthesis cluster protein B.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECO_CLOAB
Sequence: MALFKSRGVVLKSQDINENDKIIWIFTEKMGKISVIARGAKKNRSKYLPITINFCFGNFVFFKGKSMFSLNEGEIIDSFQEFLSDFDTLTYCSYLCELIDISMAEGESNRDLFKEFVSTFYLIKNKVGDIETLSRAFELKLLRYTGYNLNLDYCSKCKKRINSASYISYKYYGGICGDCSKEGGMSVTPAAYSSLNYLSKLPIEKVYRVNLNDNIKNEMFEILRGFISQNYAKIPKSLDLLNIIKEE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SYI_NOCFA
Sequence: MADDSNSAYPRVDYGAGTGAAFPDLERRVLEAWAADDTFRASIENRSGAAEFVFYDGPPFANGLPHYGHLLTGYVKDVIPRFQTMRGKRVDRRFGWDCHGLPAEIEAEKQLGITDKSQIDAMGLAEFNAACKSSVLRYTGEWRDYVTRQARWVDFDNDYKTLDLDFMESVMWAFKSLYDKGLIYQGFRVLPYSWYEQTPLSNQETRLDDAYKMRQDPAVTVDMVLSVPGEHPLRELDGANALIWTTTPWTLPSNLAIAVHPDVRYVHLRAADGTRYVLAAERVSHYSREFGEDATVLAEFEGAALVGLSYRPPFDFFLGHPNAHRVLAADYVTTDSGTGVVHMAPAFGEEDMEVCSANDIELVQPLDPGGRFTSMVPPYEGLMVFDANPVIIKDLKAAGKLLRHETIEHSYPHSWRSGQPLIYMAVPSWFVAVTKFRDRMVELNKQITWVPEHIRDGQFGKWLEGARDWNISRNRYWGSPIPVWVSDDPAYPRVDVYGSLEELERDFGVRPTDLHRPAIDQLTRPNPDDPTGRSMMRRVPEVLDCWFESGSMPYAQVHYPFENKEWFDSHFPGDFIVEYNGQTRGWFYTLHVLATALFDSPAFKTVAAHGIVLGDDGLKMSKSKGNYPDVNEVFDRDGSDAMRWFLMSSPILRGGNLIVTERGIREGVSHALRPLWNAWTFLQLYASKPGEWRTDSTHVLDRYILAKLAQTRDGMTEALEVYDIAGACEELRTFADALTNWYVRRSRSRFWSEDRDAVDTLHTVLEVATRLAAPLLPLISEVIWRGLTGGRSVHLADWPAAADLPADPELVSTMDEVRTVCSTVLSLRKAKNLRVRLPLAEVTIAAPDAERLAPYADIVADEVNVKKVDLTTDVAVHGRFELAVNARAAGPRLGKDVQRVIKAVKAGDWTESADGVVSAAGITLLPEEYTQRLVAAEPESTAALPGNAGLVVLDSVVTEELEAEGWARDLVRELQETRKSLGLDVSDRIHVVLEVPEARRSWAQTHRDLIAGEILATSLEFGTAGEPAAELAGGVRASVRKA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNMT_BOVIN
Sequence: MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRCLAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGAFDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVREALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
What is the function of this protein?
Catalyzes the transmethylation of nonepinephrine (noradrenaline) to form epinephrine (adrenaline), using S-adenosyl-L-methionine as the methyl donor (PubMed:5412063).  Other substrates include phenylethanolamine and octopamine (By similarity).  Also methylates normetanephrine (PubMed:13863458, PubMed:5412063).
What are the official names of this protein?
Phenylethanolamine N-methyltransferase, PNMTase, Noradrenaline N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.
Protein: RS3A_PYRIL
Sequence: MSEKQKAVAAQERVTISKRDPWALKKWFSVYAPSYLGGVFLAEVPASEPQKLLLRTLEVSLFDITKDLSHLPIKLRFQIHKVDGLKAITRFKGLELTRDYIRSLVRKGTSKVSAIVEVKTKDGWVMRIAVLAITTHRIGSAQKSAMRKRMFDVLTRKASEMDIGQFLKEVLEGLLTADLFVAGKKIAPLRKVEIAKIKVLKYPPEEEQTTVKELTTETVAAS
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: LPLA_SALDC
Sequence: MTTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTHIVLAALNSLGVMADASGRNDLVVKTPDGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVANLTELLPGITHEQVCQAVTEAFFAHYGERVDAEVISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGVITRAQVFTDSLNPAPLEALGERLQGCQYRVDVLEQACESLIAEFPAQKGELRELAAWMAQAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA24_ARATH
Sequence: MGKENAVSGNSIPIHGRPVTRALASALRASSKLITSSEVAATTQNQGRVLRAKSKRTALDEKKANAPKKRAVLKDITNVTCENSYTSCFSVAVENIKQIKKGRQSSSSSKVASSSATSQVTDAKVEVVSNSAGASLSVFTDTSLGTNETSYSIIAKPSSRSPPRPFGTVERSCGGASSPKFVDIDSDDKDPLLCSLYAPDIYYNLRVAELKRRPFPDFMEKTQRDVTETMRGILVDWLVEVSEEYTLVPDTLYLTVYLIDWFLHGNYVERQRLQLLGITCMLIASKYEEIHAPRIEEFCFITDNTYTRDQVLEMESQVLKHFSFQIYTPTSKTFLRRFLRAAQVSFPNQSLEMEFLANYLTELTLMDYPFLKFLPSIIAASAVFLAKWTLNQSSHPWNPTLEHYTTYKASDLKASVHALQDLQLNTKGCSLNSIRMKYRQDKFKSVAVFSSGELPDKLFIS
What are the official names of this protein?
Cyclin-A2-4, G2/mitotic-specific cyclin-A2-4, CycA2;4.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: PYRDB_BACCR
Sequence: MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLSVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLDKVMNSELPWLEQFDLPIIANVAGSQAEDYVAVAKEISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEVPVYVKLSPNVANIVEIAKAIENAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQAVNIPIIGMGGIETAEDVIEFFYAGASAVAVGTANFIDPFVCPTIIEELPALLDELGFDHISECQGRSWKQTCHSR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAT6A_XENLA
Sequence: MYQTLTITSAQGPLSYDPSPGTFMHSAASSPVYVPTSRVGSMLTSISYLQGTGASQGAHSVNSHWSQATSESSSFNNSSPHTSSRYHYPPSPPMHNGSTRDTGYSSSLTVSSRDQYTPLARSLNGSYGSHYTPYMAPQLTSAWPAGPFDNTMLHSLQSRGAPISVRGAPGDVLDELPESRECVNCGSVQTPLWRRDGTGHFLCNACGLYSKMNGLSRPLIKPQKRVPSSRRIGLACANCHTSTTTLWRRNTEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKTLNKSKSSSSNGNSSHQISMTPTSTTSSTNSDDCIKNGSPSQNTTPVVASSLMSTQQTESTSPNSNTLKYTGQDGLYSAVSLSSASEVAASVRQDSWCALALA
What is the function of this protein?
Transcriptional activator that binds 5'-GATA-3'-containing motifs within gene promoters (By similarity).  Regulates cardiac-specific transcription during embryogenesis and thereby cardiogenesis.
What are the official names of this protein?
GATA-binding factor 6-A, Transcription factor xGATA-6a.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOD_PELPB
Sequence: MQELDIAGVGSVRVTRKNDNVVVIEKDLATEQMILAMGPQHPSTHGVLKLECLTDGEVITEAEPYLGYLHRCFEKSCEHVDYPAIVPYTDRLDYLASMNSEQAYAMAVEKLLDIEIPRRVEFIRVIVAELNRIASHLVAIGTYGIDLGAFTPFLFCFRDREIILGLLEWASGARMLYNYIWIGGLAYDVPSDFFKRVGEFVTYFRPKAVELCNLLTENEIFVKRTRGIGIMPADVAINYGWSGPMLRGSGVKWDLRRNDPYSVYPELDFSVPVPDGKVSVVGDCLSRHLVRAYEMDESLKIIEQCIDKMPTAEGFNPRSAIPKRIRPKAGEVYARAENPRGELGFYIMSDGKSTKPLRCKARSSCFVNLSAMKDLSKGQLIPDLVAIIGSIDIVLGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UCC1_YEAST
Sequence: MNQSDSSLMDLPLEIHLSLLEYVPNELRAVNKYFYVLHNHSYKEKSLAWIAEDNYIWAVVKHSLCLYVKSLDPLRQHAREIIQETKEPGFNVPLCMTKYIADSWYIVYNALQYPGKIINMGWDKYTKSQDSNGSDSTSNFNSRPKERTLMQSLTALPVNFWSRRKDEPTPVNVWFYVKNAHVARYIPKIITEIGICNYGPKQIVASAGYINELITSEGIYCVNLGHLPRLYDEQIFEGTGTTHLPLELKAIDRTDSDVCINGDLVLLGYDFIPYQISKPWLLFRIEPVNSIEAIFNYSECSFSYQFAWSLACLQSEEKISFPRDTIIGHGLPYKPSKLIRIFVYKHPEQKQDLGQEIALPNWNTPYLRR
What is the function of this protein?
Substrate recognition component of the SKP1-CUL1-F-box protein E3 ubiquitin-protein ligase complex SCF(UCC1) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:10582239, PubMed:25982115).  The SCF(UCC1) complex acts as a metabolic switch for the glyoxylate cycle and regulates the level of CIT2 protein to maintain citrate homeostasis (PubMed:25982115).
What are the official names of this protein?
F-box protein UCC1, Ubiquitination of citrate synthase in the glyoxylate cycle protein 1.
Protein: MIAA1_MYCUA
Sequence: MRPLAIIGPTGSGKSQLALDVAERLAGEVPAEIVNADAMQLYRGMDIGTAKLSVAARRGIPHHQLDVLNVAETATVARYQQAAAADIEAIIARGHVPIVVGGSMLHVQSLLDNWSFPATDPAVRARWEECLAELGVGELHAELARRDPAAAATILPTDGRRIVRALEVIELTGQPFAASAPRIGAAQWGTAIIGLDCDTPILDDRLAVRTDSMFERGLVEEVRVLLRAGLRDGVTAARALGYAQVLAALDAGGGAELLDDAREQTYFGTRRYVRRQRSWFRRDHRVHWCDAGATGPSDRVAMVDEALRVWRHVT
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 1, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 1, DMAPP:tRNA dimethylallyltransferase 1, DMATase 1, Isopentenyl-diphosphate:tRNA isopentenyltransferase 1, IPP transferase 1, IPPT 1, IPTase 1.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL13_BRUME
Sequence: MATFSQKPAEVVKKWVLIDAEGLVVGRLASLVANRLRGKHKATFTPHVDDGDNVIIINADKVVLTGKKYTDKKYYWHTGHPGGIKERTARQILEGRFPERVLEKAIERMIPRGPLGRRQMKNLRVNAGPNHQHEAQQPEVLDVAALNRKNKGNA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ASSY_DROME
Sequence: MPKETVILAYSGGLDTSCVLKWLLDKQYEVICVLADVGQKEDFTAAEKKALKIGAKKVIVADVKQSFVEDYIWPAVQMGLVYEERYLLGTSLARPCISVALMEVAREYGAKYLAHGATGKGNDQVRFELCAYALKPDLKIIAPWRDVEFCCQFQGRQDLIAYAQQHGIEVSAKPATPWSTDANILHISYESGILEDPNTVAPENLYEMTVDPLTRAPRDPVHLVIQFDRGLPSSVEDLPGGRVYTKPLEMLDFLNKLGGSYGIGRIDIVENRFVGLKSRGVYETPGGTILFAAHQDLEVFALDREVLRTKQVLRDRMADYVYNGFWFSPEAIYARKCIELAEQRVSGKVTVELAPGYCRAIARKAAKDVGALYNEQLVSMDVHGGYVPQDAGGFIAINAVRIREHVRAFGAYDVPTKKN
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
Protein: VH23_RFVKA
Sequence: MGITHEFHIFLVDENVSLKSVSLLKGDSYGCNIHLKNSECKYITFILVLEPDWSEIAEAKPIRIRLNGKKMRTQLLTKTLMSIIYKAVIYVEENALVQFYSDTDRLYTDMYPTFLIDMDKQHYHILDNGYTYTYIDSFISECDKQRYLTSDIGENGYEDSTEEEDNEEDTDGVCLYCLEEEEEEDEDEDEDEDEDEEE
What is the function of this protein?
Plays a role for multiplication of the virus in different cell types.
What are the official names of this protein?
Probable host range protein 2-3.
What is the protein family that this protein belongs to?
Belongs to the poxviridae C7 protein family.
Protein: SH3L1_HUMAN
Sequence: MVIRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPATGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEVQAKQQA
What is the function of this protein?
Appears to function as an adapter protein that bridges proteins together or proteins with mRNAs (PubMed:34331014).  May function as a ubiquitin ligase-substrate adapter (PubMed:34331014, PubMed:34870550).  Additionally, associates with translating cytoplasmic ribosomes and may promote the expression of specific mRNAs (PubMed:34331014, PubMed:34870550).
What are the official names of this protein?
Adapter SH3BGRL, SH3 domain-binding glutamic acid-rich-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SH3BGR family.
Protein: GUAC_LACLM
Sequence: MNNLNSVFDYEDIQLIPNKCVINSRSEADTSVKLGNYTFKLPVVPANMQTIIDDKIAEMLAKEGYFYIMHRFEAENRAAFIKKMHKDGLIASISVGVKADEHAFIREISAEALIPEFITIDIAHGHADSVIKTIQLIKRLMPQTFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVKWCAKAASKPVIADGGIRTHGDVAKSIRMGATMVMVGSLFAAHEESPGQTVERDGQLFKEYFGSASEYQKGEHKNVEGKKILLPHKGSLKDTLKEMEEDLQSSISYAGGRDLSALTKVDYVVVKNSIWNGDAI
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: ACPS_GEOMG
Sequence: MIFGTGIDIVDITRFERFLEERNTRLFERLFTIHEQEYCAGKAHSAQHYALRFAAKEAFLKACGLGLREGLTWHDVEVVNDSLGKPDLRLYGKAQQLFADMNLSKTFVSLSHDGNFAVAMVVLERV
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIC27_PONAB
Sequence: MAAIRMGKLTTMPAGLIYASVSVHAAKEEESKKQLVKPEQLPIYTAPPLQSKYVEEQPGHLQMGFASIRTATGCYIGWCKGVYVFVKNGIMDTVQFGKDAYVYMKNPPRDFLPKMGVITVSGLAGLVSARKGSKFKKITYPLGLATLGATVCYPVQSVIIAKVTAKKIYATSQQIFGAVKSLWTKSSKEESLPKPKEKTKLGSSSEIEVPAKTTHVLKHSVPLPTELSSEAKTKSESTSDVQISEVGGKIIGTWGPNVTNSGVLRI
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol.  Plays a crucial role in crista junction formation and mitochondrial function.
What are the official names of this protein?
MICOS complex subunit MIC27, Apolipoprotein O-like, Protein FAM121A.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Mitochondrion.
Protein: UXAB_KLEP3
Sequence: MKTLNRRDFPGAQYPDRIIQFGEGNFLRAFVDWQIDLLNEHTDLNAGIVVVRPIATDFPPSLSTQDGLYTTIIRGLNEQGEAVSDARLIRSVNREISAYADFDAFLRLAHNPEMRFVFSNTTEAGISYHAGDRFDDAPPVSYPAKLTRLLFERYQHFAGAADKGWVIIPCELIDYNGEALQALVLRYAAEWQLPQAFIRWLTSANTFCSTLVDRIVTGYPRDEVAALEAQTGYKDAFLDTAEHFYLFVIQGPASLAAELRLDKLPLNVRIVDDIKPYKERKVAILNGAHTALVPVAFLAGIDTVGEAMNDAEICAFVEKAIYDEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKYRTRILPQLLAGQQKSGQLPPRLTFALAALIAFYRGEREGERYPVQDDAEWLARYQTLWARHRDRQMSTRELVTAVLSVEAHWEQDLSQIPGLVEQVTADLDAILSRGMRDAVQPLC
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: COFG_METBF
Sequence: MTYSKNVFVPVTNICRNRCGYCGFRREPGQPGARLMKPEEILPVLENGAKAGCTEALFTFGEYAEEVSEYRKWLKKLGYSSTLEYLLFLCEASIDIGILPHTNAGIMTRTELKALKPLNASMGLMLESTATLDAHKDCPGKLPELRLNTIREAGKLQIPYTTGLLIGIGEIREDRIESLEAIAGLHREYGHIQEVIIQNFAPKPGTPMENFPAPSIEEIIDTICLARQILPSDIAVQVAPNLIDPKALIAKGVTDLGGISPLTIDWINPEAEWPDIKELQRKLSPILLKERLPIYPQYVRKKWYSDRIGGLIEQLSDTDGYRKKP
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: Y4WC_SINFN
Sequence: MLSTNSEQTRRKPNAVDAHVGQRIRQRREWQNMSQTTLGEAIGVTFQQVQKYEKGVNRVGAGRLQQISKALKVEPSYFFEDTLNKIRSEERSASNQINIPPEVVEFVVSKEGIELIRAFSRVGDYRVRRRIVMLVKSLGAHER
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator y4wC.
Protein: RR2_AMBTC
Sequence: MARRYWDINLEEMMGAGVHFGHGTRKWNPRMAPYISGKRKGIHITNLTRTARPLSEACDLVFDAASRGKHFLIVGTKDKAADSVASAAIRARCHYVNKKWLGGMSTNWSTTETRLHKFRDLRAEQKMGRFKRLPKRDAAMLKRQLSHLQTYLGGIKYMTGLPDIVIIVDHQEEYTAIRECLTLGIPTICLIDTNCDPDLADIPIPANDDAIASIQLILNKLVLAIREGHYSYLGSH
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ENGB_LEGPC
Sequence: MPINLYSKAVFLKSAARVNQLPEDSGYEVAFAGRSNAGKSSALNCLTNNKNLARTSKTPGRTQLINLFSLDEQRRLVDLPGYGYAKVAMEVKLEWQKNLAHYLEARQCLRGLILLMDVRHPLKDLDQILVNWALHRELPVHILLTKADKLSRSEVKNAVLKVRQYYELAEHLVSVQAFSSVKKDGVEELISLLDRWYEWN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ANXA1_PIG
Sequence: MAMVSEFLKQAWFIDNEEQEYIKTVKGSKGGPGSAVSPYPTFNPSSDVEASHKAITVKGVDEATIIEIHTKRTNAQRQQIKAAYLQEKGKPLDEALKKALTGHLEEVALALLKTPAQFDADELRAAMKGLGTDEDTLNEILASRTNREIREINRVYKEELKRDLAKDITSDTSGDYQKALLSLAKGDRSEDLAINDDLADTDARALYEAGERRKGTDLNVFITILTTRSYLHLRRVFQKYSKYSKHDMNKVLDLELKGDIENCLTVVVKCATSKPMFFAEKLHQAMKGNGTRHKTLIRIMVSRSEIDMNDIKACYQKLYGISLCQAILDETKGDYEKILVALCGGD
What is the function of this protein?
Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades.  Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors.  Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration.  Promotes resolution of inflammation and wound healing.  Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2.
What are the official names of this protein?
Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein, p35.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, cilium. Basolateral cell membrane. Lateral cell membrane. Early endosome. Cell membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Apical cell membrane. Membrane; Peripheral membrane protein. Endosome. Secreted. Secreted, extracellular space. Cell membrane; Peripheral membrane protein; Extracellular side. Secreted, extracellular exosome. Cytoplasmic vesicle, secretory vesicle lumen. Cell projection, phagocytic cup. Note=Colocalizes with actin fibers at phagocytic cups. Secreted, at least in part via exosomes and other secretory vesicles. Detected in exosomes and other extracellular vesicles. Secretion is increased in response to wounding and inflammation (By similarity). Alternatively, the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in the protein translocation from the cytoplasm into ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (By similarity). Detected in gelatinase granules in resting neutrophils. Neutrophil adhesion to endothelial cells stimulates secretion via gelatinase granules, but foreign particle phagocytosis has no effect. Displays calcium-dependent binding to phospholipid membranes (PubMed:3020049).
Protein: GLNE_SALHS
Sequence: MTPLSSPLSQYWQTVVERLPEGFTETSLSAQAKSVLTFSDFALDSVIAHPEWLAELESASPQADEWRHYAGWLQEALAGVCDDASLMRELRFFRRRIMVRIAWAQTLSLVDDETILQQLSHLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALHLLPENDVAQLRVAYLFLRRLENLLQSINDEQTQTLPADDLNRARLAWGMKAENWPQLVGELTDHMANVRRVFNELIGDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQVLTLIADFRKELDKRPIGPRGRQVLDQLMPHLLADVCSREDAVVTLSRITPLLAGIVTRTTYLELLSEFPGALKHLIMLCAASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELRQYLLRVPEEDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWTQMVARYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEAWTWEHQALVRARVVYGDPQLTSQFDAVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDNVRILELLAQNGIMDDHEAQALTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: KTHY_YERE8
Sequence: MNSKFIVIEGLEGAGKTTARDTVVATLRAQGINDIVFTREPGGTPLAEKLRDLIKQGIDGEVLTDKAEVLMLYAARVQLVENVIKPALARGSWVVGDRHDLSSQAYQGGGRGIDINLMTSLRDTVLGEFRPDLTLYLDLPPVIGLARARARGELDRIEQESLAFFERTRERYLELAATDSSIKTIDASQPLEQVSESISQVLKQWLTSRETA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.