PharMolix/UniProtQA huggingface dataset:
Protein: NUOI_EHRCJ
Sequence: MICKKKFLSPIINLFHSIIINCKGMYITLRYMFKPKVTLNYPLEKGPLSTRFRGEHALRKYKNGEERCIACKLCEAICPAQAITIEAQERDDGSRRTVRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEYATETREELMYNKSKLLHNGQVWEEAIDFRIKKNSQFY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUSB_LACP7
Sequence: MTRREIREHLFRMLFRKEFHEPTELEEQVLFYFDSLESITPEQQEYLNVRFDKINEKLGEIDTILANASSGWKLNRMGKVDLNIMRLATFEIRFDDEVPVKVAINEAIELAKKYGGDSSASFVNGILAKVID
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: LEXA_NOCSJ
Sequence: MATPQTGKKTPSRRVSELPDGPPDATGLTPRQQRVLAHIKDSIEKRGYPPSMREIGEAVGLTSSSSVAHQLKTLEEKGFLKRDPHRPRALEVFLPEVMAARRSMSAAEESSFDETGVGDALPAAQYVPVVGRIAAGGPILAEERVEDVFPLPRQLVGDGQLFLLEVRGDSMIEAAICDGDYVAIRQQPTAENGEIVAAMIDGEATVKTFQRKDGNVWLLPHNPAYDPIDGTHATILGKVTAVLRRV
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MNMG_STRGC
Sequence: MSHNFTESYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEMLAFMPCNPSIGGSAKGIVVREVDALGGEMAKNIDKSYIQMKMLNTGKGPAVRALRAQADKEVYSKEMRKTVENQENLTLRQTMINEILVEDGKVIGVKTATHQEYAAKAVIVTTGTALRGEIIIGDLKYSSGPNHSLAAIPLADNLRDLGFEIGRFKTGTPPRVKASSINYDVTEIQPGDEKANHFSYTSRDEDYVKDQVPCWLTYTNAESHEIIQNNLHRAPMFSGIVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLVHSIKGLENAEMMRTGYAIEYDMIMPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGINAALKIQGRPELILKRSDGYIGVMIDDLVTKGTVEPYRLLTSRAEYRLILRHDNADMRLTEMGREIGLVDDERWARFEIKKNQFDNEMKRLESIKLKPVKETNAKVEELGFKPLTDAVTAKEFMRRPEVSYQDVVQFIGPAAEELDEKIIELIETEIKYEGYISKALDQVEKMKRMEEKRIPANIDWDDIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEGKARSISKNKEKQNHV
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAD51_RABIT
Sequence: MAMQMQLEANADTSVEEESFGPQPVSRLEQCGINANDVKKLEEAGFHTEEAVAYAPKKELINIKGISEAKADKILTEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARGFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVTVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
What is the function of this protein?
Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR).  Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange.  Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template.  Recruited to resolve stalled replication forks during replication stress.  Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR.  Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.  Also involved in interstrand cross-link repair.
What are the official names of this protein?
DNA repair protein RAD51 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RAD51 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion matrix. Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with RAD51AP1 and RPA2 to multiple nuclear foci upon induction of DNA damage. DNA damage induces an increase in nuclear levels. Together with FIGNL1, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) or camptothecin (CPT) treatment. Accumulated at sites of DNA damage in a SPIDR-dependent manner. Recruited at sites of DNA damage in a MCM9-MCM8-dependent manner. Colocalizes with ERCC5/XPG to nuclear foci in S phase (By similarity).
Protein: DCEB_SHIFL
Sequence: MDKKQVTDLRSELLDSRFGAKSISTIAESKRFPLHEMRDDVAFQIINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVNMVADLWHAPAPKNGQAVGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCGPVQICWHKFARYWDVELREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADTGIDIDMHIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDEEALPQELVFNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRLGREGYTKVQNASYQVAAYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLRLRGWQVPAFTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQQNSFKHT
What is the function of this protein?
Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction.  The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions.  The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria (By similarity).
What are the official names of this protein?
Glutamate decarboxylase beta, GAD-beta.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: SYQ_CLOPS
Sequence: MSNAEHSSNFIRNIIIDDLDSKKHDTIITRFPPEPNGYLHIGHAKSIVLNFELGKEFNGRTNLRFDDTNPIKEDTEYVESIKEDVHWLGYNWSELHFASNYFDEMYKRALLLIKKGKAYVCDLTPEEIKEYRGTLTEPGKESPYRNRSVEENLDLFERMRKGEFEDGSKVLRAKIDMSSPNINFRDPIIYRIAHASHHNTGDKWCIYPMYDFAHPLEDAIEGITHSICTLEFADHRPLYDWFVKECEMENIPRQIEFARLNITNTVMSKRKLKQLVDEGIVDGWDDPRMPTVAGLRRRGYTPKSIRNFCKAIGVAKADSTVDYQMLEHFIREDLQETAPRAMAVINPLKLVITNYPEGKSEILEIENNPKDESAGKRAVTFSREIYIEREDFMENPPKKYFRLFPGNEVRLKGAYFVKCNEVIKDENGEVTEIHCTYDPETKSGTGFTGRKVKGTIHWVDANNCIPAEFRLYEPLILDDCEENEGKHFLEQINPNSLTICKGFIEPSAKDAKPQDKYQLFRHGYFNVDPNFTSDDNLVFNRIVSLKSSFKLK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYLT2_MOUSE
Sequence: MERRGRMAKTPTGQTHQSPVSKRERKPSMFEKESYAQILRERLRESFHDVQYVEPPFDDSIADVGKEWKSALAKLKFANSYRMEPLKKFQAHLVETKIQQILKDSLKDVKYDDKAPHLSLELADGILAAVKEFAYHRYKFIIQVLFIQKTGQAINIASRWIWDVAWDNWVEAKHETESYVVLALVFALYCE
What is the function of this protein?
May be an accessory component of axonemal dynein and cytoplasmic dynein 1.  Candidate for involvement in male sterility.
What are the official names of this protein?
Dynein light chain Tctex-type protein 2, LC2, T-complex testis-specific protein 2, T-complex testis-specific protein 3, T-complex-associated testis-expressed protein 3, Tcte-3, T-complex-associated testis-expressed protein 4, TCTEX-4, TCTEX-2, Tctex1 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain Tctex-type family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasmic granule. Membrane; Peripheral membrane protein. Note=Found on the surface of sperm tail. Stored in cytoplasmic granules during spermatogenesis.
Protein: NU4LM_MIRLE
Sequence: MTMVYANIFLAFIMSLMGLLMYRSHLMSSLLCLEGMMLSLFVMMTVTILNNHFTLASMTPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL27_ECOLI
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27, Large ribosomal subunit protein bL27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SRY_PUSCA
Sequence: MFGVLNSNDHRAAVQQRNIPAFGRTSFEPWTDNPTSNYRCETGGNGRDSGQNRVRRPMNAFMVWSRDQRRKVALENPQMQNSEISKQLGYQWRMLTEAEKWPFFEEAQRLQAMHREKYPDYKYRPRRKALPQKSDKLLPAASSSMLCRQVLVDEKWYPFTYRDSCSRAAHSPMEDQLSSSRPVNIANSLLQQEHHYRSTSLGDSPETLAAHLSADPPFYPKEQLGLSDAYFP
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: DYR_STAES
Sequence: MTLSIIVAHDKQRVIGYQNQLPWHLPNDLKHVKQLTTGNTLVMGRKTFNSIGKPLPNRRNVVLTNQASFHHEGVDVINSLDEIKELSGHVFIFGGQTLFEAMIDQVDDMYITVIDGKFQGDTFFPPYTFENWEVESSVEGQLDEKNTIPHTFLHLVRRKGK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: HYBE_ECOLI
Sequence: MTEEIAGFQTSPKAQVQAAFEEIARRSMHDLSFLHPSMPVYVSDFTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVSEKIGLQLPYGTMTFTVGELDGVSQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVTNPDVPHAGRRALLFGRRSGENA
What are the official names of this protein?
Hydrogenase-2 operon protein HybE.
What is the protein family that this protein belongs to?
Belongs to the HupJ family.
Protein: K2C2_XENLA
Sequence: KGSTKRANLDPLFEKYISDLKRYLDNLINEKGRLQQELRTLQDLVEDFKKKYEDEINKRTKAENDFVVLKKDVDAAYMIKTELEAKVDTLTSEINFFRTLFAAELSQVHDQVTDTSVVLTMDNNRDLNLDSIIKEVKCQYEQIAQRSKLEAEALYDQRYKQLQQTVEGHGDSIKNSKTEISDLNLKIQRLKAEIENVKKQIAFLNQSIAGAEERGNLALKDAERKLKDLEDAERKLKADMARQLKEYQELMSAKLALNLEISTYRYMLEGEEGRMSGQISNNVSISVISGGSSVYTALGGAAGGMGGGGGMGGGMGGGMGMGGGMGMGGGMGMGGGMGMGGGMGGGMGMGGGMGMGGGMGMGDGMGSGHGGGYGNEACFGGGMGYEGGSMHGGGSSYGHSGGKTSVAIASTTSTTKRSY
What are the official names of this protein?
Keratin, type II cytoskeletal I, Clone PUF164.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RSSA_BRANA
Sequence: MAANGSTQLSQKEADIKMMCAAEVHLGTKNCNYQMERYVFKRRNDGIYIFNLGKTWEKLMMAARVIVAIENPQDIIVQSARPYGQRAVLKFAQYTGANAIAGRHTPGTFTNQMQTSFSEPRLLILTDPRTDHQPIKEGALGNIPIIAFCDTDSPMRFVDIGIPANNKGKHSIGCLFWLLARMVLQMRGTIRPAQKWDVMVDLFFYREPEETKPEDEDEVAPQAEFGLPAPEYGGGDQWTTAAIPDAAWPGEAQAPISAAPAAGSWNDSAAPAAAEGGWDAAVPPTTAVTNWE
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA, Laminin receptor-like protein, p40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBHL_RHILV
Sequence: MTIQTPNGFTLDNSGKRIVVDPVTRIEGHMRVEVNVDENNIIRNAVSTGTMWRGIEVILKNRDPRDAWAFTERICGVCTGTHALTSVRAVENALGITIPDNANSIRNLMQLALQVHDHVVHFYHLHALDWVDVVSALSADPKATSALAQSISDWPLSSPGYFKDIQTRLKKFVESGQLGPFKNGYWGNASYKLPPEANLMAVAHYLEALDFQKEIVKIHTIFGGKNPHPNWLVGGVPCPINVDGTGAVGAINMERLNMVTSIIDQLIEFNDKVYVPDIMAIGSFYKDWLYGGGLSGKNVLAYGDVPEHANDYSEASLKLPRGAIINGNLAEVFPVDHADPEQIQEFVTHSWYKYPDESKGLHPWDGITEPHYELGPNAKGTKTNIEQLDEGAKYSWIKAPRWRGNAMEVGPLARWVIGYAQNKAEFKDPVDKVLKDLGLPVTALFSTLGRTAARALESQWAGYQMRYFQNKLIANIKAGDSNTAFVDKWKPETWPKEVKGVGFTEAPRGRLAHWIRIKDGKIDNYQCVVPTTWNGSPRDPTGNIGAFEASLMDTPMSNPTQPLEILRTIHSFDPCLACSTHVMSPDGQEMARVQVR
What is the function of this protein?
This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions.
What are the official names of this protein?
Uptake hydrogenase large subunit, Hydrogenlyase, Membrane-bound hydrogenase large subunit.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: OBG_HAEIG
Sequence: MKFIDESLIRIEAGDGGNGCVSFRREKFIPKGGPDGGDGGDGGDVYLQADENLNTLIDYRFNKRFAAERGENGRSSDCTGRRGKDIILPVPVGTRAIDNDTKETLGDLTQHGQKMLVAKGGYHGLGNTRFKSSVNRAPRQKTMGTPGEKRDLLLELMLLADVGMLGFPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVKVDDSHSFVVADIPGLIEGAADGAGLGIRFLKHLERCRVLIHLVDIAPIDGSNPADNVAIIESELFQYSEKLSEKPRWLVFNKIDTMSDEEAEERVREITEQLGWEEDYYLISAATGKNVPPLCRDIMDFIIANPREAETQQVAPEEIKFKWEDYHQEQLAEYQFDDDEDWDDDWTEEDDDEDWDDDWSEEDDEGIEFIYKP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPYK_LACLA
Sequence: MNKRVKIVSTLGPAVEIRGGKKFGESGYWGESLDVEASAKNIAALIEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAGHKVGFLLDTKGPEMRTELFADGADAISVVTGDKFRVATKQGLKSTPELIALNVAGGLDIFDDVEIGQTILIDDGKLGLSLTGKDAATREFEVEAQNDGVIGKQKGVNIPNTKIPFPALAERDDADIRFGLSQPGGINFIAISFVRTANDVKEVRRICEETGNPHVQLLAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIVVTATNMLESMTYNPRATRSEISDVFNAVIDGTDATMLSGESANGKYPRESVRTMATVNKNAQTMLKEYGRLHPERYDKSTVTEVVAASVKNAAEAMDIKLIVALTESGNTARLISKHRPNADILAITFDEKVERGLMINWGVIPTMTEKPSSTDDMFEVAEKVALASGLVESGDNIIIVAGVPVGTGRTNTMRIRTVK
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: ANKS3_HUMAN
Sequence: MSELSDEASEPELLNRSLSMWHGLGTQVSGEELDVPLDLHTAASIGQYEVVKECVQRRELDLNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPEGQTPLMLASSCGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEAAAAGHEIIVQYFLNHGVKVDARDHSGATARMLAKQYGHMKIVALMDTYSPSLPKSLYRSPEKYEDLSSSDESCPAPQRQRPCRKKGVSIHEGPRALARITGIGLGGRAPRPRYEQAPPRGYVTFNSSGENPLEEEGLCCRDVTSPINERDVESSSSSSSREEHAFCANLGPVQSSSSSEGLARAQGLSSEASVESNEDSDHACKSSARKQAKSYMKTKNPDSQWPPRAATDREGFLAESSPQTQRAPYSGPQDLAALLEQIGCLKYLQVFEEQDVDLRIFLTLTESDLKEIGITLFGPKRKMTSAIARWHSSARPPGDALELAYADRLEAEMQELAIQLHKRCEEVEATRGQVCQEQELRAVVESCLLEQDRAREDLQARLRETWALARDAALVLDQLRACQAELSSRVRQDQPPGAATLGLAVPPADSKGWQASLQAMSLPELSGALEDRVREMGQALCLVTQSLEKLQVLNGKKWRET
What is the function of this protein?
May be involved in vasopressin signaling in the kidney.
What are the official names of this protein?
Ankyrin repeat and SAM domain-containing protein 3.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm.
Protein: ATPG_WIGBR
Sequence: MYNIKDIRQKIIGIKKTQSITSAMEKISAIKMKKSQNLLNSTKPYYEKISLLLNKLLFQNIKYKHPYLKKRQIKCIGYIVVSTDRGLAGSLNINLFKKLLYEINKSKEKKINTKLVLIGSKAISFFRFFEDEIISTISGIGDTPKISELIKPVQIMLKEYDSNIIDKIYIISNKFINTMTYVPDIKKVLPISIKKSSIKFKNLNYLYEPDFSSLFESILPRYIESLIYQSIVENISSEQSARMVAMKSAMDNSKNLIEELSLIYNKARQSNITKELTEIIAGSNNIY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BTUF_PECAS
Sequence: MTFRFLCWLTGLLLCTAAYAIPQRVISLAPHATEMAYAAGMGEQLIAVSAWSDYPPEAKKLEQVASWQGINLERILALKPDLILAWREGNPQRPLEQLANFSIPIVYLDAKTLDDIPASLRQLATYSRHPEQAERAATDFQQQIGELQHADEKHKAAHTAPLRVFIQFGTQPLFTSSKATLQSQIVSLCGAENIFSDSTVPWPQVSREQVLRRQPQAIIIGGASDKIANTQAFWQPQLTVPVITVNEDWFSRSGPRLLLAAQQICSQLAELKLAPSSAK
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GLYA_NOSS1
Sequence: MTRTNSDFLTNSDPAIAGLINQELQRQRDHLELIASENFTSAAVLAAQGSVLTNKYAEGLPGKRYYGGCEFIDKIEQIAIDRAKQLFGADHANVQPHSGAQANFAVFLTLLKPGDKIMGMDLSHGGHLTHGSPVNVSGKWFQVCHYGVSQQTEQLDYDQIRELALRERPKLLICGYSAYPRIIDFEKFRSIADEVGAYLLADIAHIAGLVATGLHPNPLPYCDVVTTTTHKTLRGPRGGLILTRDAELGKKLDKSVFPGTQGGPLEHVIAGKAVAFGEALKPEFQGYSAQVIDNARTLANQLQTRGLKLVSDGTDNHLMLVDLRSVNMTGKRADQLVSEVNITANKNTVPFDPQSPFVTSGLRLGSPAMTTRGMGEAEFTEIGNIIADRLLNPDSDTVAQDCKRRVAALCDRFPLYPHLEIPVPVLA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_HAEIG
Sequence: MKFIVKLFPEIMIKSETVRKRFAKILTSNIRNILQKYDEETAVVRHWDYIEVRSKNEENREELIALLQRIPGIHHFLEVEEKPFTDLHHIFELTLADVAQQLQGKTFCVRVKRKGKHKFSSIEAERYIGGGLNQHIESTKVRLKNPDVTVRIDIEDDKMMLVKARHAGIGGYPIGTQEDVLSLISGGFDSGVSSYMLIRRGSRVHYCFFNLGGAAHEIGVKQMAYHIWQRYSASHKVRFIAINFEGVVGEILEKVDNGQMGVVLKRMMVRAASKVAQRFNIEAIVTGEALGQVSSQTLTNLRLIDEAADALVLRPLITHDKEQIIAMAKEIGTDDIAKSMPEFCGVISKNPTIKAVREKILAEEGNFNFEILESAVQNAKYLDIRQIAEETEKEVVEVEAISVLGENEVILDIRSPEETDEKPFESGAHDVIQMPFYKLSSQFGSLDQSKNYVLYCERGVMSKLQALYLKENGFSNVRVFAKNIH
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAP30_MOUSE
Sequence: MNGFTPEEMSRGGDAAAAVAAVVAAAAAAASAGNGNAAGGGAEVPGAGAVSASGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFKSIPVNEKDTLTCFIYSVRNDKNKSDLKADSGVH
What is the function of this protein?
Involved in the functional recruitment of the Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes.  Capable of transcription repression by N-CoR.  Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones.
What are the official names of this protein?
Histone deacetylase complex subunit SAP30, 30 kDa Sin3-associated polypeptide, Sin3 corepressor complex subunit SAP30, Sin3-associated polypeptide p30.
What is the protein family that this protein belongs to?
Belongs to the SAP30 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSTB_HYPNA
Sequence: MDTDHRPQAEGAVLTPSAEAPPVAAPRIDCRDIRVFYGADQAIHNVSLSFPDRAVTALIGPSGCGKSTFLRCLNRMNDTIENCRVEGQILMDGQDINDHSIDPVLLRSRVGMVFQKPNPFPKSIYDNIAYGPRIHGLASSREDLDAIVEKSLRRAGLWEEVKDRLQAPGTSLSGGQQQRLCIARAIAVRPEVILMDEPCSALDPVATARIEELIDELRKRYCIVIVTHSMQQAARVSQRTAFFHLGNLIEMGETEQIFTNPREKRTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBA5_DROPE
Sequence: MTNAIDELQAIIAELKTEVEEQRAVIRQSRDRIEHMSAEVRMNIVKNYERIRDKTVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLFFTPDQAGLSKVEAAARTLTFINPDVRIETHNYNITTIDNFDNFLNTITGDGTVAGEPVDLVLSCVDNFEARMAINAACNEKCLNWFESGVSENAVSGHIQFLRPGDTACFACAPPLVVAENIDEKTLKREGVCAASLPTTMGITAGFLVQNALKYLLNFGEVSDYLGYNALNDFFPKMTLKPNPQCDDRNCLLRQKEFQARPKPVVVQEEAPTDEPLHASNDWGIELVAEDAPSNAPTDLSQSTDVGQGLRLAYEAPEKSSAEATQAATAPVDDTSLEDLMAQMKSM
What is the function of this protein?
E1-like enzyme which activates UFM1.
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.