PharMolix/UniProtQA huggingface dataset:
Protein: OFUT6_ARATH
Sequence: MAFQRRRNNYYNRLRRLLPFICAVSGALLILFALLSILSPPPDDSDRRISKHINYGANDEKKNTPVVFTVPRGGGRSDRDIWRSWNAEFFYGCCNASSKFPNAKAITRNDRYLAIATSGGLNQQRTGIVDAVVAARILNATLVIPKLDQKSYWKDASDFSNIFDVDWFMSFLSKDVKIIEKLPQKGGQTWSPRRMRVPRKCNEKCYINRVLPVLQKRHAVQLNKFDYRLSNKLRDDLQKLRCRVNYHALKFTDPILEMGNELVRRMRKRSKHFIALHLRFEPDMLAFSGCYYGGGEKEKKELGTIRRRWKTLHVNNPEKQRRQGRCPLTPEEVGLMLRALGYGSDVHIYVASGEVYGGEKSLAPLKALFPHFYSKDTIATKMELKPFSSYSSRMAALDFLVCDESDVFVTNNNGNMARILAGRRRYFGHKPTIRPNAKKLYKLFMSKENTTWEEFASRVRTFQKGFMGEPKEVRAGKGEFHENPAACICEDTDAKVKAGKMDSRKFGKKEQKEDEDAELSSSETDYEEDQTDLQDRGLYNGTRLDYDDALSVSEEPELEEMLSD
What are the official names of this protein?
O-fucosyltransferase 6, O-FucT-6, O-fucosyltransferase family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: HYAL3_HUMAN
Sequence: MTTQLGPALVLGVALCLGCGQPLPQVPERPFSVLWNVPSAHCEARFGVHLPLNALGIIANRGQHFHGQNMTIFYKNQLGLYPYFGPRGTAHNGGIPQALPLDRHLALAAYQIHHSLRPGFAGPAVLDWEEWCPLWAGNWGRRRAYQAASWAWAQQVFPDLDPQEQLYKAYTGFEQAARALMEDTLRVAQALRPHGLWGFYHYPACGNGWHSMASNYTGRCHAATLARNTQLHWLWAASSALFPSIYLPPRLPPAHHQAFVRHRLEEAFRVALVGHRHPLPVLAYVRLTHRRSGRFLSQDDLVQSIGVSAALGAAGVVLWGDLSLSSSEEECWHLHDYLVDTLGPYVINVTRAAMACSHQRCHGHGRCARRDPGQMEAFLHLWPDGSLGDWKSFSCHCYWGWAGPTCQEPRPGPKEAV
What is the function of this protein?
Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid.  Involved in induction of the acrosome reaction in the sperm.  Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate.  Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage.  Has no hyaluronidase activity in embryonic fibroblasts in vitro.  Has no hyaluronidase activity in granulosa cells in vitro.
What are the official names of this protein?
Hyaluronidase-3, Hyal-3, Hyaluronoglucosaminidase-3, Lung carcinoma protein 3, LuCa-3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Cytoplasmic vesicle, secretory vesicle, acrosome. Endoplasmic reticulum. Early endosome. Note=Mostly present in low-density vesicles. Low levels in higher density vesicles of late endosomes and lysosomes. Localized in punctate cytoplasmic vesicles and in perinuclear structures, but does not colocalize with LAMP1. Localized on the plasma membrane over the acrosome and on the surface of the midpiece of the sperm tail.
Protein: TAL_TRIEI
Sequence: MVTNHLLEIENLGQSIWMDNLSRNIIESGELKSMIGKKGIRGITSNPAIFEKAIAGNAIYDADIEAGIKASKSVIEIYESLVFKDIRDACDIFMPVYEETKGLDGYISIEVPPTIAKDTESTISEAIRYYTAIGRENLMIKIPGTPEGLPAVTRVISEGINVNVTLLFSVESYINTAWAYIEGLEARAAKGEDIDKIASVASFFLSRIDSNIDGLIDEKLKKVTDETVKAKLEAVKGKVAIANAKIAYQEYKKIIQSDRWKALSAKGAKEQRLLWASTSTKNPAYSDVMYVDELIGPNTVNTLPPPTIDACADHCDVDNRVETNIEVTKEVMENLKDPDININIDQVMEQLLVEGIDKFIKPFTSLINSLEEKVKKLTPV
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_CHLAB
Sequence: MSILADTEKKMAAALEFFTKEVRSFRTGKANPALVETVTVDVYGTTMRLSDLASISVADTRQLVISPYDANNVSAISKGIIAANLNLQPDVEGSIVRIKIPEPTAEYRNEVIKQLRRKSEEAKVAIRNIRRESNDKLKKDSDLTEDAVKGMEKKIQELTDKFCKQIDKMSKQKEVDLSSI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBI_STAA1
Sequence: MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAISKLNEKDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYYNTYYKYKGAIDQTVLTVLGSGSKSYIQPLKVDDKNGYLAKSYAQVRNYVTESINTGKVLYTFYQNPTLVKTAIKAQETASSIKNTLSNLLSFWK
What is the function of this protein?
Plays a role in the inhibition of both the innate and adaptive immune responses.  Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH.  By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis.
What are the official names of this protein?
Immunoglobulin-binding protein Sbi.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin-binding protein Sbi family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Occurs both extracellularly and associated with the cytoplasmic membrane where only the domains I and II are exposed to the extracellular media. Membrane association occurs via binding to lipoteichoic acid.
Protein: SRD1_CAEEL
Sequence: MATPTEIAYNRAALIESLQFTFVMDEVGKHLSEVICGFGIVLNLLLIYVIFKRTPKHMRSYAVLLFNFAIFDLLTCVASLLACQKTIFSGLSLTYIFHGPCKYVSSSLCFFCHCFVCHAMAHSQWILLISFIYRYRVLVDGAPDTKKMIVIVSLFYAMSAVIFLFYFWDIGDTNDLKQIMYDLHPQYHYDDREIWGDIVVSGNTTVLTIPSLIAIFYMTMPCVPIYFIIHYFRDKTLSTLASNALSMSPATKASHQKLIMALSIQAAIPIFWLVASGIFTLAEFGIIDGPIPENITFRLMDCIPSSSPLVAFIFIAPYREGLLRIISKTGIYRKQENRVSSVVEKFNQPPKQPTNPAQQSANNDAAKTEKV
What are the official names of this protein?
Serpentine receptor class delta-1, Protein srd-1.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srd family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PYRC_LISMF
Sequence: MYVLKNGQVLNASGELENKDVLIQNGKVNLIADSIEVTSGEEFDATGKLIAPGFIDVHVHLREPGGEHKETILTGTQAAARGGYTTICSMPNTKPVPDSKEVMESLQAKIKETAKVRVLPYASITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNSLIYGGVVHDGIFAEKEGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIRVTAEVSPHHLILDEEAIPGNDGNWKMNPPLRSKEDRAALLEGLLDGTIDFIATDHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVKTNEWTLKQLIDWMTVKPAECFKLPYGKLEEGSVADIVVLDLEKEANIDPATFYSKGKNTPFVGETCIGWPVATFSEGTLVYNEGEIK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: PNS1_YARLI
Sequence: MNDEEKHLAAPANAYQPNMHYQQQQEKQTGYNAEYDTHQGGYNQNQNQDYYNHSQGGYQMDNMGQHGGYQGNPNDNYNNQQPPPYTPDFPPDYNYKPNPNAATFDEAFAVPKPKWNDKIGLVILALIFSGYLALSIIVIRAYAQTHSFQGWGIYSGENDYSLNTHTLILYAFVLATAMVLSLLYFIAARVWTKQFIWITYILHLLFSWGTAIYYLVVGYYSAGIVFIVFAALTTWWFWCSRKRIPFATIVLQTLIDVTRANPSVLVISAVGTVVGACFGTWFSFTIVSIYVKYDPDNRNPGCMTTGGSCSNGKLIGLILFAIFCGYYLTEVIKNVIHVTISGVYGSWYYCSKSDQGMPKHAAMSSFRRAVTYSLGSISLGSLIVSIINFIRQILSVLQQDARQSGDTLATVLLCFVQCCFGVLDWLVTYFNHYAYSYIALYGKAYVPSAKATWKLMQTRGIDAMVNDSLIGSVLSFGASFVAYAAALVAYCFLKYTDPSYNSGGGFYAPVVGLAFVIALQVSNITNVSLKSGCSTFFLALARDPEVLRVSYPQIYEEICRTYPPARDKLDI
What is the function of this protein?
Probably involved in transport through the plasma membrane.
What are the official names of this protein?
Protein PNS1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPD_HELPJ
Sequence: MKDILNALYHQKDLNDEEVKKLFTLIIDEKVSPAQLGAVLCALKIKGESFKEISVAATTLLEHAPKPFNSGLDLIDNCGTGGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSADLLENLGVNIEMNPMQLENCFKQSHFGFLFAPLYHQSFKKSAPLRKELFTKTIFNCLGPLINPLRPKIQLLGVYDKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDITHACELKNNEILEYDLSAKDFDLPPYDLKELQIENAKESVQACLDILENKGKDSHTMVVAANVASLLYLSHRAKDLKEGVSMTLEHLKTKAPYAHLQKIIRLSHA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ATG8_CRYNB
Sequence: MVRSKFKDEHPFDKRKAEAERIRQKYQDRIPVICEKAEKSDIPTIDKKKYLVPADLTVGQFVYVIRKRIKLAPEKAIFIFVDDILPPTAALMSSIYDEHKDEDGFLYVLYASENTFGDLEQYAISE
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Participates also in membrane fusion events that take place in the early secretory pathway.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
Protein: URE1_CUPPJ
Sequence: MVKISRQAYAEMFGPTTGDRVRLADTGLVIEVEKDFTIYGEEVKFGGGKVIRDGMGQSQRMAKDCVDTVITNALIVDHWGIVKADIGLKGGRIAAIGKAGNPDIQPGVTIVVGPGTEVIAGEGMIVTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGPATGTFATTVTPGPWYMERMLQAIEAYPMNIGLLGKGNASQQAPILEQVEAGAIGLKLHEDWGTTPAAIDTCLSVADATDTQVAIHTDTLNEAGFVEATIAAFKGRTIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTRPYTVNTLDEHLDMLMVCHHLDPAIAEDIAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVIIRTWQTAHKMAAQRGKLPGDPNDARGGHDNFRVKRYIAKYTINPALTHGIAHEVGSIEVGKWADLVLWRPACFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRPMFASAGGALHKSSLTFVSQAALAANVGERYGLAKTLSAVRGTRTVSKRDMVHNDWQPHVTVDPETYQVVADGQLLMCDPATELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_SHIDS
Sequence: MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAGLQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKQGIRITEGRHPVVERVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGIANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELENISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FAC2A_CALOF
Sequence: MGKGASNKKVLERVPITKPPFEYNDLKKAVPPHCFSRPLFRSFYFLLHDIIVTCILFYVASNYIPMLPGFLSYIVWPVYWISQGVFLGRLWMIGHECGHHSFSNYRWVDDSVGFLIHTATLTPYFSFKYSHRNHHAHTNSMEYDEVHIPKRKSEALDLYFEFLGNNPMGLMITMLCKLTFGYAAYIMFNYTGKKHKSGGLASHFYPQSPLFNDSERNHVLFSDVGICIVLYACYRIVMVTGAMSAFYVYGIPWVIMSAILFAATYLQHTHPSIPHYDTTEWNWLRGALSTIDRDLGFFNMNKTHYHVIHHLFPVIPEYHAQEATEAIKPILGQYYKYDGTPFLKALWREMKDCIYVESDQGQKKQGIYWFKNKI
What is the function of this protein?
Fatty acid conjugase converting 18:2(9Z, 12Z) to calendic acid 18:3(8E, 10E, 12Z) (PubMed:11067856, PubMed:11161042, PubMed:12383261).  Converts alpha-linolenic acid (18:3(9Z, 12Z, 15Z)) into 18:4(8E, 10E, 12Z, 15Z) (PubMed:11067856).  Also has weak activity on the mono-unsaturates 16:1(9Z) and 18:1(9Z) producing two conjugated double bonds at delta(8) and delta(10) position (PubMed:11161042).
What are the official names of this protein?
Fatty acid conjugase FAC2 A, CoFac2, CoFadX-1.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Microsome membrane; Multi-pass membrane protein.
Protein: KCNV1_MACFA
Sequence: MPSSGRALLDSPLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation.  Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily V member 1, Voltage-gated potassium channel subunit Kv8.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2 (By similarity).
Protein: OCAD1_MOUSE
Sequence: MNGRADFREPNAQVSRPIPDIGGGYIPTEEEWRLFAECHEECFWFRSVPLAATSMLITQGLISKGILSSHPKYGSIPKLLFACIVGYFAGKLSYVKTCQEKFKKLENSPLGEALRSGELRRSSPPGHYTQKPKFDSNVSGQSSFGTSPAADNIEKEALPRYEPIPFSASMNESTPTGITDHIAQGPEPNLEESPKRKGVTYEELRSKNRESYGVTLPHKTDPSVRPMQERVPKKEVKVNKYGDTWDE
What is the function of this protein?
Maintains stem cell potency (PubMed:23972987).  Increases STAT3 phosphorylation and controls ERK phosphorylation (PubMed:23972987).  May act as a scaffold, increasing STAT3 recruitment onto endosomes (PubMed:23972987).
What are the official names of this protein?
OCIA domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the OCIAD1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: CWC24_CRYNJ
Sequence: MSEAPAPVVTFKKGPSRRPAQSRQRRRSPSPLDPVAEASASASGSNVVRPERKSLANPLVQGTKRRRTNANNEEEEDGVGGGLDEFDYAAEGGLTRKGDELATRANDWDLEDVDGQGQRDKKVRLDEDGEIVTDDGLYRGASAYLPTINKTRETLDKKMKSGPIKATSHVRTITLMDYQPDVCKDYKETGFCGYGDSCKFLHDRGDYLAGWQLDKLPEEGVREVEEEDEEEEVPFACLICRQPFTQPVVTKCGHYFCMGCAAKRFQKSPKCYACGAPTQGIFNIADKVIAKIEARNKARREAREERAEQTGGGGIEIGGGSDEEGSDEE
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC24.
What is the protein family that this protein belongs to?
Belongs to the CWC24 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYC_THESQ
Sequence: MRITNTLTGKKEEFVPIQPGVVRMYVCGPTVYDLIHVGNARPAVVFDVFRRYLEYRGYRVIMVQNFTDIDDKIINKANQLGVDYKTVADTFIAEYWRDAHALGIRPANFHPRTTDFVDDIVEIIERLVEKGVAYQTETGVYFDVRKFEKYGELSKKKIEDLIAGARVEVDETKKFPLDFSLWKKAKPGEPCWKSPWGEGRPGWHIECTVMSVKILGESFDIHAGGEDLVFPHHENEKAQAEALTGKVFARYWMHNGMVRFLGDKMSKSTGNIFTVREAVKRYGRDGLRYMILSKHYRSPMDFSEELLQDYSRAVKRVWEILGRYEKSGDIGIPKRNAVYEEYVNRFVEALDDDFNTPVAVSLIFELARNLSKAMDDNDREDALLYYHLIRREFGPVLGLFDLNEEKKEVSSEELLKLLIEVRDVLRKEKRYDLSDRIRDHLREIGIILKDTPSGTEYTVE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_HAEDU
Sequence: MEQIVSSLWSDCLNHLQTKVSPIDYSTWLRPLQASFANEELTLYAQNPFVENWVKDKFLTEIIDLARFLSKNEQLKITIRVGNKPTEQNLSASSTNKEELTQDTVHKFKTGLNGRLTFDNFVQGKSNQLAKAVAQQVADNPGESHCNPFSLYGGTGLGKTHLLHAVGNEILKRNPQARVVYIHSERFVQDMVKALKNNTIENFKKFYRSLDVLMIDDIQFFAKKEASQEEFFHTFNSLFERNKQIILASDHFPKNIENIEERIKSRLNWGVSTAIEPPELETRVAILMKKAEERNVELPEEVAFYLGQKLRTNVRELEGAINRVSAWCNFTKRQITIDAVRETLKDLIASYDHLVTIENIQKIVAEYYNIKMADLKSKSRTRSIARPRQMAMALAKELTSHSLPEIGREFGGRDHTTVMHACKTINELRDTDNSIQEDYTNLTRKLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YE06_SCHPO
Sequence: MVSNQDNVQRNDVQKYPITRFVKRKSNVVLKKNKGAMKSNSNSRSRGNKKLKESQFSSRDNFRTTQTQASSSSEPSDNTNRLVPVVIIDNNTPKKEESNAEKLKLDKDSSSVNYENQISKPLITFSDIHETVNVPFLCLDKHDSKNEVAINSHEDSPVCLEDITGSLSSTYGNDSLGESNLEELPTSDKIKGENMGSRKKRKGFVIDSEDSDTGIPREENVTITRKTKLSSNILYSDSDTERQSDSGSKNVARQFSRIKRKRKVLSSSSEDDESSSPEDLLKPIIRSTEEMENLNELEQEVQDLDPIDEGFEEKVPRFRNPSKKAFYEKLHSLRNRSYSKLESLTSEKSDTLITKSELANESEEDDFIVDDEDTEVMMNARSLLPAEFSMTSHQGLKAHFRNFMMFIVQQAIDPIDASDISDHYLFSRRTIRKQLYSSVDSNIISSIWQSEFIKLIKTVPNMKSAKIDATYGCDACNIHTRMSTQIVYFKGMPYNEHNYKELDSFEPITKEAWMLGNSCFNRARIAHSIYHWEYKVSRHIQVELKFREASNTSEQGKNIVESIYEDLKDSNFFETTWVELCNLLKLASSSFESNFHSRSSM
What are the official names of this protein?
Uncharacterized protein C17H9.06c.
What are the subcellular locations of this protein?
Nucleus.
Protein: TYSY_METAC
Sequence: MEDKFEIGRIIRAKNISDAWYRGLNIIWNHGQVITDERGSQIREFMDLMVVIENPYTDRIPEDTAWNEERLEEYAKQLISGENAQDFEYTYGQRLRNWNEEVDQIEYVIEKLQESPTSRRATAVTWIPPVDTKVNEVPCMILDDFKIRDGKVHLTTLFRSHDFGGAYPANLYGLSKLLEYVAGRVGVEPGMITTVSISAHVYDHDWDMVENIVKGIN
What is the function of this protein?
May catalyze the biosynthesis of dTMP using an unknown cosubstrate.
What are the official names of this protein?
Putative thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_CUSRE
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIVSGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAIEAPATNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: ISP_PAEPO
Sequence: MERKVHIIPYQVIKQEQQVNEIPRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPEDVPELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKMEGNGLLYLTAVEELSRIFDTQRVAGILSTASLKVK
What is the function of this protein?
Involved in the generation of beta- and alpha-amylases from the large amylase precursor.
What are the official names of this protein?
Intracellular serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: SEPF_BACAH
Sequence: MSWSKVKYFFFDTPEEKEAAQYSYEKEQTDMKKQQDPPEQQDVTFPKAQPKQNVVSIETAKQSSKVVLLEPRTYSEAQGIADHLKGRRAVVINLQRMSTDQAVRIVDFLSGTVYAIGGDIQKIGPKTFMCTPENVDIVGAISELFGEEEDTNIKRW
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: QUEC_SHEPC
Sequence: MQKTFESKTATSKAVVVFSGGQDSTTCLIQALTQYDEVHGITFDYGQRHREEIEVAKSLAKRLKITSHKVMDVTLLNELAISALTRDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGAEAIITGVCETDFSGYPDCRNDFVKAMESALVQGMDKQLKIITPLMWLNKAQTWALADKYQQLDLVRHHTLTCYNGVIGDGCGDCPACHLRKRGLDDYLQNKAAVMAELDASEPKA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: YFHL_BACSU
Sequence: MTGLVGGGLMIIAGILIKLFPPKSINSVYGYRTRRSMSDQRLWNEANRYSASLMILSGLVIAGMGLLLGSNLFILQLILLIAACVITFMLTEKRLKIMTHSQGGDRSGRS
What are the official names of this protein?
Uncharacterized protein YfhL.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HRCA_PARXL
Sequence: MLDPRAQTLLKTLIERYIAEGQPVGSRTLSRYSGLELSPATIRNVMSDLEDLGLVISPHTSAGRIPTPRGYRLFVDTMLTVESAADEEAVMRTVKTTLQAGEPQKIVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQNRIMATQRDFSPSQLVEASNYINAHFAGLSFDDVRRRLREEIDELRGDMTTLMHAAVTASTDEADTGETVLISGERNLLEVADLSSDMARLRKLFDVFDQKTSLLQLLDVSSHAAGVQIFIGGESNLVPIEEMSVVTAPYEVNGKIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.