PharMolix/UniProtQA huggingface dataset:
Protein: RH10_ORYSJ
Sequence: MAKKKDVEVEELDEEVVAAAAAPAADGGEEQEAEPPARRPSTFAELGVVPELVAACDAMGWKEPTRIQAEAIPHALEGRDLIGLGQTGSGKTGAFALPIIQALLKQDKPQALFACVLSPTRELAFQIGQQFEALGSAIGLSCTVLVGGVDRVQQAVSLAKRPHIVVGTPGRLLDHLTDTKGFSLNKLKYLVLDEADKLLNVEFQKALDDILNVIPKERRTFLFSATMTNKVSKLQRACLRNPVKVEVASKYSTVDTLRQEFYFVPADYKDCFLVHVLNELPGSMIMIFVRTCESTRLLALTLRNLRFKAISISGQMSQDKRLGALNRFKTKDCNILICTDVASRGLDIQGVDVVINYDIPMNSKDYVHRVGRTARAGNTGYAVSLVNQYEAMWFKMIEKLLGYEIPDRKVDNAEIMILRERISDSKRIALTTMKEGGGHKKKRRKNEDDEEEEERNAPVSRKSKSFNKSRRR
What is the function of this protein?
Has ATP-dependent RNA helicase activity in vitro.  Acts as a thermosensitive RNA chaperone required for normal processing of pre-rRNA intermediates.  Required for normal cell division at high temperatures.  Required for a primary metabolism adaptation to high temperatures to support thermotolerant growth by regulating gene expression.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 10, DEAD-box RNA helicase TOGR1, Protein THERMOTOLERANT GROWTH REQUIRED1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Localization is not affected by temperature.
Protein: MAZE2_MYCTU
Sequence: MLSFRADDHDVDLADAWARRLHIGRSELLRDALRRHLAALAADQDVQAYTERPLTDDENALAEIADWGPAEDWADWADAAR
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.
What are the official names of this protein?
Probable antitoxin MazE2.
Protein: GLMU_SHEDO
Sequence: MSLNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTANSLGSQAIQLVYGYGADKLQASLGEQQVNWVLQAEQLGTGHAVAQANANINDDDTVLILYGDVPLIQQSTLNALLDARTHDGMAILTVDLPNPSGYGRIVRIDGKVVGIIEQKDANEEQLQITEVNTGIMAVPGKQLKVWLSRLSNSNAQAEYYLTDIVAMAHEDGVAIDTAQPQSAIEVEGANNRVQLALLERAYQTRAAEKLMLEGANLRDPARIDIRGEVTVGMDVMIDINVIFQGKVVLGNNVTIGAGAILIDCEIADNAEIKPYTIVEGAKLGQAASAGPFARLRPGAELKEDAHIGNFVEIKKSVLGVGSKAGHLAYIGDAQIGAGVNIGAGTITCNYDGANKHLTVIEDGVFVGSDTQLVAPVTIGKNATLGAGSTICKDVAENELVITRVKQRHIQGWQRPIKQKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_ENT38
Sequence: MLNKLSRLLEQAGISLTDHQKNQLVAYVDMLNKWNKAYNLTSVRDPNEMLIRHILDSIVVAPHLRGERFIDVGTGPGLPGIPLSIVRPECHFTLLDSLGKRVRFLRQVQHELKLENIEPVQSRVEAFPSEPPFDGVISRAFASLNDMVSWCKHLPAQDGRFYALKGLVPDDEIAQLPEGYSVESIAKLQVPQLEGERHLVVIKPNHF
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADET1_ACIBA
Sequence: MFDPIGKSGDAFALAKDYALEAKNWGADLSLKAYVDERVAAEDLKVGKCDGAIISGLRGRQFNKYTGSLDAVGALTNMKTAINAYKLLSSPMAAKNMVVGPYEIAGLGTIGPAYLFVNDRSINTLAKAAGKKIGVFKYDEAQPKLVQHVGGQAVSVDVTNAGAKFNNHEIDIVPAPIVAFKPFELYKGLGEKGAIVRFPLTQISADFIIRKDQFPAGFGQKSRTWVASQLNRTFGIIAKYESDIPSKYWMDIPKNEQLNYMKMMREARIQLTKAGIYDPKMMNFLKKVRCKENPSNFECALNDE
What is the function of this protein?
Mediates antimicrobial resistance via active efflux.  Contributes to resistance to antibiotics such as chloramphenicol, erythromycin and novobiocin (PubMed:21212056).  May be part of a tripartite ATP-independent periplasmic (TRAP) transport system (Probable).
What are the official names of this protein?
Probable solute-binding protein AdeT1.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 7 family.
Protein: HCDH2_CAEEL
Sequence: MLSSTCTAAVRGLSTTAQLSKINNVTIIGAGLMGSGIAQVSANAKLNVTVVDSNQSALEKAQQGIANSLKRVAKKKHADDAAAQTALVSSVLDRIKMSTNVSDSVKDADLVIEAIVENIDIKRKLFAEVEVAAKPTTLITTNTSSLRLADIGLNLKDKSRFGGLHFFNPVPMMKLLEVVRHTETSDATFNQLVDYGKTVGKTTVACKDTPGFIVNRLLVPYMFEALRLYERGDASMEDIDVAMKLGAGYPMGPFELSDYVGLDTCKFIMDGWHAQYPEEVAFTPSPLLNSLVDSGKNGRKSGEGFYKYK
What are the official names of this protein?
Probable 3-hydroxyacyl-CoA dehydrogenase B0272.3.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ERD1_KLULA
Sequence: MDAESVEPFLVYLPIPQRVVVLVLLGLWLWTWFLKVSVSYYDVSKVIVSNESTGLPYFNTSTKIHQSSLKLFKSISRVIIPWQLVCIILFQYSFTNNVSNKLLWFFLNVSPLLELFYIFAMILRSSAMVARCFKRILWVADIEPKPYRNNYIIISDTLTSYSKPLVDLAIYATFLFHDPTNVKCQVERYENAISLNIDVLVGVLPSLVRMIQSLREFTRGRSQKKDGSQLFNAFKYAGNIPIMLVTVYTRYYNLGPLGMMYWFMFWNSAYSFWWDVTMDWKLELFDFVNGDTSVNNNNSSNKADGLLRSILLYRKNAWYYSAMALDFILRFVWFWEYISGHSVFYGELNIFWLQILEIIRRWIWLFFKVEVEYIATTEGGKMDE
What is the function of this protein?
Required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus.
What are the official names of this protein?
Protein ERD1.
What is the protein family that this protein belongs to?
Belongs to the ERD1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SUCC_BRUA1
Sequence: MNIHEYQAKRLLHTYGAPIANGVAVYSVEQAEEWAKTLPGPLYVVKSQIHAGGRGKGKFKELPADAKGGVRLAKSVEEVVANAKEMLGNTLVTKQTGEAGKQVNRLYIEDGADIERELYLSILIDRSVGRPAFVVSTEGGMDIEAVAEETPEKIVTVAIDPAKGVTDEDANKLADALKLEGGAREDGLKLFPILYKAFTEKDMSLLEINPLIVMTNGRVRVLDAKVSFDNNALFRHPDIVELRDLTEEDPKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPAVEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLEGTNVELGKKIINESGLNVISADDLDDAAQKIVAAVKGN
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: COMB_DEIGD
Sequence: MRLRVDLLPHGNYPDVVLVVDVLRATTTAVTYLERGADALLLTATPEVALGLRGAAGEGGVLLGGERGGLPIPGFDFGNSPVEAAAQNFTGRVVVMNTTNGTGAAHIAAQTGKHVLLAALTNAHAAARRARALASEEIAIVCAGTDARVGLEDVYAAGVLAEYLLALGEFRIDDGARIALTIRRNAGDPLEALSSSGHGQHLVGLGLGDDVRYAAQVSTSTVVPVLDATQTTPEVLRFVGG
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: KPRS2_STRPN
Sequence: MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQVNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDRIACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCDKGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKAILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDSVATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Putative ribose-phosphate pyrophosphokinase 2, RPPK 2, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 2, Phosphoribosyl diphosphate synthase 2, Phosphoribosyl pyrophosphate synthase 2, P-Rib-PP synthase 2, PRPP synthase 2, PRPPase 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_CMVFT
Sequence: MDKSESTSAGRNRRRRLRRGSRSAPSSADANFRVLSQQLSRLNKTLSAGRPTINHPTFVGSERCKPGYTFTSITLKPPKIDRGSYYGKRLLLPDSVTEYDKKLVSRIQIRVNPLPKFDSTVWVTVRKVPASSDLSVAAISAMFADGASPVLVYQYAASGVQANNKLLYDLSAMRADIGDMRKYAVLVYSKDDTLETDELVLHVDVEHQRIPTSGVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: THIC_DESPS
Sequence: MTRNLEKKMSIREDAQQGKVTPLFEQCAAVESMSVERLMAGVSDGTIAITKNKNHAFSKVIAIGAGTSTKVNANLGSSKDINSLEEELKKLAVAIKAGADTIMDLSMGGDLQKIRQEILKNCSVPLGTVPIYQVAAEVVAAGKEIVDMTVERMFEVIEQQAKDGVDFMTIHCGINRHLQERLKNQPRTMGVVSRGGSFTLDWMNHHKRENPMYEYFDDLLAILKEHEVTLSLGDGIRPGCLADATDRNQIQELITLGELTERAWAAGVQVIVEGPGHMPLNQIKANVLLQKQMCKGAPFYVLGPLVTDIAPGYDHITGAIGGAIAASAGADYLCYVTPAEHLKLPNCSDVHEGVIASKIAAHAADIVKGLPGAIEKDNAMAKCRKELDWKGQIELSIDPAKSAQYRHEGGGDATDACSMCGEFCALKVFERSQK
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: NUOI_ACIC1
Sequence: MPNILPGPLRGFGVTFGTMFRRVTTEQYPDEKKPTMPRYHGRHVLNRHPDGLEKCIGCELCAWACPADAIYVEGADNTEEERYSPGERYGRVYQINYLRCIFCGYCIEACPTRALTMSNEYELADDNRADLIYTKEQLLAPLAPGMEPPPHPMRLGDTKDYYRGTPAAHMLSGEDDAASETTLDRSDDHSATYEEAERP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NU2C1_HELAN
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFILTATIGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTENIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYLLVLIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MAST_VESXA
Sequence: INWKGIAAMAKKLL
What is the function of this protein?
Mast cell degranulating peptide.  Activates G proteins that couple to phospholipase C.
What are the official names of this protein?
Mastoparan-X, MP-X.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Mastoparan subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COBQ_VIBCH
Sequence: MKKWLMVQGTTSDAGKSVLVAGLCRVLARRGIQVCPFKPQNMALNSAVTPDGGEIGRAQAVQAQACGIAPSVHMNPVLLKPNSDTGAQVILQGRALSNMEANAYHDYKKVAMDTVMDSFQRLQQEYEAIMIEGAGSPAEINLRENDIANMGFAEKADVPVIIVADIDRGGVFAHLYGTLALLSESEQARVKGFVINRFRGDIGLLQSGLDWLEQKTGKPVIGVLPYLHGFDLEAEDAIAAQQNLSADRQLRVAVPVFTRISNHTDFDPLRLNPNIDFRYVGQGESLSGADLIILPGSKSTRADLAYLRSQGWDKEILRHLRLGGKVMGICGGFQMLGEWVHDPLGIEGEAGSSEGLGLFAMQTELTAEKRLTNVKGHLTLDGQTVAAQGYEIHAGHSSWAADQKSPIILSDGSLDGLVSDCNQGFGTYLHGIFDRPETALRICQWAGAKEIEAYDHRAAQERAIDRIADAIEQHLDLTLLWPDL
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RNH2_PELUB
Sequence: MKILAGVDEVGRGSLIGPVYAAAVILNNSIDKKLLKDSKTLTKDKREELEKYIKKNSIWAIGQASTKEIEKINILHASLLAMKRAILKLKIKPSLVLIDGNKLPDLKNYKLEYVIKGDQKIPSISAASIIAKVSRDKFITKLSKEFNNYGWDTNSGYGTKEHLKAIKQFGITKYHRKTFSPISDLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAA_LEVBA
Sequence: MLSVPDYEFWFVTGSQHLYGEEQLKSVAKDAQDIADKLNASGKLPYKVVFKDVMTTAESITNFMKEVNYNDNVAGVITWMHTFSPAKNWIRGTELLQKPLLHLATQYLNNIPYADIDFDYMNLNQSAHGDREYAYINARLNVNNKIVYGYWGDEDVQDQIARWEDVAVAYNESFKVKVARFGDTMRNVAVTEGDKVEAQIKMGWTVDYYGIGDLVEEINKVSDADVDKEYADLESKYTMVQGDNDAETYKHSVRVQLQQYLGIKRFLEKGGYTAFTTNFEDLWGMEQLPGLAAQLLIRDGYGFGAEGDWKTAALGRVMKIMSHNDRTAFMEDYTLDLRKGHEAILGSHMLEVDPTIASDKPRVEVHPLDIGGKADPARLVFTGSEGDAIDVTVADFRDGFKMIGYAVDANKPEGETPNLPVAKQLWTPKVGLKTGALEWMKAGGGHHTMLSFSLTEEQMEDFATMVGMTKAFIK
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: RL331_MYCBO
Sequence: MARTDIRPIVKLRSTAGTGYTYTTRKNRRNDPDRLILRKYDPILRRHVDFREER
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: GCH4_SYNFM
Sequence: MIDVQSRFDSRNIRVDKVGVKDIRYPITVMDKTNGIQHTVASVNMYVNLPREFKGTHMSRFIEILNEFHGNLDIREFPSILQSVQEHLSAESAHLELSFSYFIKKLSPVTGCAGLMEYGCRVAGSLDSNRGHDLVLEVNVPISTVCPCSKEISSYGAHNQRGMVRLAVRFKKFVWIEDLVRLVECAASSEVYSVLKRPDEKFVTESAFDNPKFVEDVVRDIAKELKADQNISWFLVDVENFESIHNHSAYACIERSK
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: RS16_BARHE
Sequence: MALKIRLSRGGSKKRPYYHIIVADARSPRDGRFLERVGAWDPMLPKDGPRVKLNEERIQYWLGQGAQPTDRVLRFLDAAGLKKRPTRNNPHKGEPGKKAQERIAAAKQAAEEAAAAKTESAPISEEV
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: CAPSD_HBOC3
Sequence: MPPIKRQPGGWVLPGYKYLGPFNPLDNGEPVNKADRAAQSHDKSYSELIKSGKNPYLYFNKADEKFIDDLKNDWSLGGIIGSSFFKLKRAVAPALGNKERAQKRHFYFANSNKGAKKSKNNEPKPSTSKMSENEIQDQQPSEPNDGQRGGGGGATGSVGGGKGSGVGISTGGWVGGSYFTDSYVITKNTRQFLVKIQNNHQYKTESIIPSNGGGKSQRCVSTPWSYFNFNQYSSHFSPQDWQRLTNEYKRFRPKGMHVKIYNLQIKQILSNGADVTYNNDLTAGVHIFCDGEHAYPNATHPWDEDVMPELPYQTWYLFQYGYIPTIHELAEMEDSNAVEKAIALQIPFFMLENSDHEVLRTGESAEFNFNFDCEWINNERAFIPPGLMFNPLVPTRRAQYIRRNGNTQASTSRVQPYAKPTSWMTGPGLLSAQRVGPAASDTAAWMVGVDPEGANINSGRAGVSSGFDPPAGSLRPTDLEYKVQWYQTPAGTNNDGNIISNPPLSMLRDQTLYRGNQTTYNLCSDVWMFPNQIWDRYPVTRENPIWCKQPRSDKHTTIDPFDGSIAMDHPPGTIFIKMAKIPVPSNNNADSYLNIYCTGQVSCEIVWEVERYATKNWRPERRHTALGLGIGGADEINPTYHVDKNGAYIQPTTWDMCFPVKTNINKVL
What is the function of this protein?
Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1.  The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid.  The capsid encapsulates the genomic ssDNA (By similarity).  Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region.  The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (By similarity).
What are the official names of this protein?
Minor capsid protein VP1.
What is the protein family that this protein belongs to?
Belongs to the parvoviridae capsid protein family.
What are the subcellular locations of this protein?
[Isoform Minor capsid protein VP1]: Virion. Host nucleus. Host cytoplasm. Note=Slightly detected in the cytoplasm, mainly seen in the nucleus. SUBCELLULAR LOCATION: [Isoform Minor capsid protein VP2]: Virion. SUBCELLULAR LOCATION: [Isoform Major capsid protein VP3]: Virion. Host nucleus. Host cytoplasm. Note=Slightly detected in the cytoplasm, mainly seen in the nucleus.
Protein: PRM1_ASPNC
Sequence: MLFSKSGRTIFPLLPPYGVQDPNGVQGRVIPVHPDGSTPYLGLRARLSQVWLNRWTVLLLLVLARVLMAASSIKTDMNRAKSEALSACTSVESMGDAMVSMPHYLAEGVNELTADGVNAAIDGLKMLLMLTLTGVEELVIFFVKVMYQTYLCLFTLVVHGVVDVGLSLIEDVTDVLNSTVKTVAKDIAKVTETFEDDYNTLISKINGVASLFGGSVPTLNISSEIDKLENVQLSSSIDKDLQKINDSIPNFNEVMNFTENVIRFPFDEVKKLVNESLGNYTFNASALPVPAKKTLTFCDKNDGINSFFAGATDIILTARKIFIAILVVAAIIACVPMAWQEIRRWHTMKERSQLVRKEAHDPMDVVYIVSRPHTAAIGIKAASRFSNSRRQILVRWVIAYATSPAALFVLLLALAGLLSCLCQFILLSAVKRTVPELSNEVGDFAEEVVDVLQNTSAQWANDANKVIQNVDDELNDHVFGWVNTSTGALNDTLNTFVNKTIGVLNDTFGGTLLYEPLLDVFDCLVGLKVESVQKGLTWVSDHAHIDFPLLPNDTFSRGAEGSLNSSDASESFLADAGDETSNKITEVVYKVISALEKALLIEVIIASCILLVWVINAMFGIIRALTLFWGRDKNRGEGGPAPPNSRPNPGSGPDSHGFIDVPLTSLPSHRDADETAARSQPAPRYEVATSQGSSAAVVSSELEYPDEKVGFAGQRNALRVDGVSDLRGSSYVEYGIEKY
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein prm1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 3MGH_CLOBM
Sequence: MRLTRDFYAKDARVLAKELLGKVLVREVDGIKLKGKIVETEAYIGAIDKASHAYGGRRTKRTEPLYGKPGIAYVYFIYGKYFCFNIISKTEGEAEGVLIRALEPLENINLISKLRFNKEFEELNNYQRKNITSGPSKLCMAFNINRDNNWEDLCESSSLYVEDVLYNDFEIIETVRVGIDYAEEARDFLWRYYIKDNAFVSVK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: RF1_HAEIN
Sequence: MKDSIIAKLESLKERYEELEALLGDVSVISDQDKFRAYSKEYSQLEEVVKCFNRWTQLNQNIEEAEILLDDPEMKEMAQMEIEESKAEIEEVEQQLQILLLPKDPNDEYNCYLEIRAGTGGDEAGIFAGDLFRMYSRYAESKRWRVEMLSANESEQGGYKEVIVKVTGEGVYGQLKFESGGHRVQRVPKTESQGRIHTSACTVAVMPELPESEMPEINPADLRIDTYRSSGAGGQHVNTTDSAVRITHIPTGIVVECQDERSQHKNKAKAMSVLASRIVQAEQERQAAEQTDMRRNLLGSGDRSDKIRTYNYPQGRVTDHRINLTIYRLDEVMNGKIDELIQPIITEYQADQLAALSEQN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARE_STAA8
Sequence: MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMPTGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGKTKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLHDVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREGLTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGKKNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTIGAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKTKRVEYAWTDEELNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQEDQSILDNSEVQVLENDQFDEEEI
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit B, Topoisomerase IV subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family. ParE type 2 subfamily.
Protein: DBHB_SERMA
Sequence: MNKSQLIDKIAAGADISKAAAGRALDAVIASVTDSLKAGDDVALVGFGSFTVRERSARTGRNPQTGKEIKIAARKVPAFRAGKALKDAVN
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU-beta, HU-1, NS1.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PANB_TRIV2
Sequence: MPVTTQQLIQWKQQGRSIVALTAWDYTIAQILDAAGVDLILVGDSMAVMLGYKTTLPITLEEMLHHAKAVCRGVQRALVVVDLPFLTYQESIPQAINSAGRILKETGAQAVKLEGGYPAMVETITRLVQAGIPVMGHVGLTPQSVHQLGLRQQGKTQETAQRILNEAIALEQAGVFSIVLEHIPADLAMQITQKLSIPTIGIGAGSHCDGQVLVTSDVLGLSERQPPFAKVYTNLRATITKAVQDYAAEVRDRQFPE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_PELPD
Sequence: MAKLGLNVDHVATVRQARGGMEPDPVTAAALGELAGAEGITIHLREDRRHIQDRDLEILRRTVKTKLNLEMAATQEMVRIALRTKPEQVTLVPEKRQELTTEGGLDVILNLKAITDAVKRLRDGGIVVSLFVDPDQEQIKAANKSGADYIEIHTGAYADAPDWPSQKRQLEEIDAAIKLASKVGMGVNAGHGINYVNIKPLAALGGIEEYNIGHSIMARAILVGMDRAVKDMVELIKYA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.