PharMolix/UniProtQA huggingface dataset:
Protein: DPOE_KLULA
Sequence: MSAFKGSTTAKFVGRGNEYPTQANSFAQVAQQLLNSKKVDEIDEMMGFPRFIPSPALSDSKVGWLSNMHPTIISQEMLEEEGNLHSATVSGISGVDFYFIDEEGGSFKTTVTYDPYFFVSCTDETRIHDIEEYLKKTLEQCIKKVELVLKDDLAMNNHLVGLKKHLIKLSFSNSNQLFEARRILRPILKINEDENGKKDIYNTGSDYSTRDVKTLIEDIREYDVPYHVRVSIDKNIRVGKWYAVSAQGLVELEEKVTFADPVVLAFDIETTKAPLKFPDSAIDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKDEYKGQFAIFNEPDEMALLQRFFEHIRDVRPTVISTFNGDFFDWPFVENRAKFHGLNMFDEIGFAPDSEGEYKSSYCTHMDCFRWVKRDSYLPQGSQGLKAVTQAKLGYNPLELDPELMTPYAYEKPQILSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDEVLRKGTGTLCEMLLMVQAYQNSVLLPNKHTDPIERFYDGHLLESETYVGGHVESLEAGVFRSDLKNDFKIDPTVIDILLEDLPYALKFCIEVENNGNMEDVTNFEEIKQQITAQLTDLKINNKRNELPLIYHVDVASMYPNIMTTNRLQPDSMKDEKDCASCDFNRPGKSCDRRLKWAWRGEFFPAKMDEYGMVKRALQNELFPNKNPKSKKQFLTFEELSYSDQVSHIKKRLTDYSRKVYHRVKVTETVEREAIVCQRENPFYVNTVRSFRDRRYEFKGLAKLWKGKLSKIKPDDVHSKDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGANIIQMARSVVERIGRPLELDTDGIWCILPKSFPENFEIKLRNGKKLFLSYPCSMLNYKVHQKYTNHQYQDLVDPMKFKYQTKSDNSIFFEVDGPYKAMILPTSKEEGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFKLFLEGTTLESCYAAVATVANRWLDVLDSKGAMLETEDLIELICENKSMSKTLKEYQGQKSTSITTARRLGEFLGEAMVKDAGLQCKFIISSKPHNAPVTERAIPVAIFSSDLHVKRTFLRRWLLDSSLNDFDPRAIIDWDYYRERLASVVQKIITIPAALQNIKNPVPRVEHPDWLRKKIAVSEDKFKQTSLNRFFKSTKAPPEVKDIEDSFDEHSANKSRIAKVTYKRKSKRRNGDTALEEESLLLPSEMPPMLDDYVGWLQYQKTKWKIQHIDRKKREKLFGKTSRASDRSALGNLIRKHVESYADKSWEILQCKPSIDLGVVEIYALIDRKIQLLKVNIPKTVLMNFKTENFPSGGIENCIVEKSNAELPNVKGINNESSSQLFKLTMSEDTYFNEVNKASSVLNNENVLGIYESSISSNERVIMRLGTCIQFSSEKMGALGKGLQNGFHMKNLHPVEADRYLQRFDLDIAYLLHFVTDIGYEFYFLYKAWEDVVEIFVLKPSTHAQEVSNKAIESLYNEIYEKKFEKLDKYYDLIKINKNVSFNVNDYTELKRLLKDLSKMLQNIKEEKGSHTMVILQSPYTHRVAKLLQPLNAFPVVEIATAETHLPALNWQGQLMRKAVNHILSLGSWISNLITLSKYSNIPICNLKVDNLGYIIDLMYARQLKKNNIVLWWNDKSPLPDHGGVERDFDPRKAELMTDLVFPIMNNPDIYDDVIFEISVYNSVVNTVLSSTMLNEAEGTDLAQNSTSKEESFGFVEDSFSSSALSVLRALLKELWDDALGDNITADSLVHAFIGWVYNPDAKLFDYALRYHIHTLTQKAVLQLINEFKLAGSSLIFADRNKLLIKTQKRSVENSYAYGQYLMKAIRSKPMFAYLDLKIDRYWDVLIWMDKYNYGGRACLQIEDKEVQSFQAYSHWHIKDFLPAIYQQEFDDWLVVILDSMVKTKEAYHERNASTQRLTQLPKNTLADSDVDSQTDSLGGFTHNFSKALIKRAEKLYKNQQEYILDPNFGKDYLSPTIPGSHLVVKNPLLELVKYLSHILSLSSNHLLEGRALRKELLKTFEIREFDRLAEFKDPSTSFVIPSFICEHCSYISDIDICRESMERVFICQSCNRSLNKNLIEEHVIERLQAQVASFITQDVKCNKCHKIKEDAMSPYCPCSGKWELAVSKESFMAQLQIFKNLAESFDFRTLKETLNDFL
What is the function of this protein?
DNA polymerase II participates in chromosomal DNA replication.
What are the official names of this protein?
DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: METAS_SHEB9
Sequence: MPVRIPDHLPAAEVLESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHTSIDHMNTFYRDFEAVRHKNYDGLIITGAPLGQIDFEDVVYWDHIREIIDWSQEHVTSVLFLCWAAHAGLYHLYGLNRKILQQKRSGVFVHRRTSQHFPLLRGFDDEFFAPHSRFAEMDVEEIRQHPQLQLLAESDEAGAYLVLSRNNRNLFVMGHPEYQKSTLNEEYQRDLSQGLDPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMTAMTPWESR
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOBI_ECOLI
Sequence: MYIFITHFFTEYVILKYLLPI
What are the official names of this protein?
Uncharacterized protein YobI.
Protein: TIG_HALHL
Sequence: MQVSVETTEGLGRRMTVQVPAERVENEVERRLKDLSGRVKMDGFRPGKVPVKVVRKQYGAQVRSEVLSEVVQQTYSEALEQESLRPAGNPHIEPKRTGEGEDLEYEASFDVLPEIEVAGLDQIQVERPQVEITDADLDNVLERLRKQHADYQEVDRAAQDEDRVVIDFHGTIDGEAFTGNSAEDAPLILGAGQLPEAFEQGLQGAKAGQELTVEHKFPDELAEPSIAGKTAVFQVTVKRVEEPQLPELDDDFAARLGIQEGGVEALREAVRGNLERERHQAVRQRLKRQVLDQLADQNELELPKSLIDGEIQALRQQSGASAEGELPESERSAYEDVASRRVKLGLLVNELVRSQGIQLDRERMMTQLREMAANSGQDPSEALQQIAQDRQMMQSLEASVIEEQVVDWLLEQVQTEDKTLSFDELMNSEDGDQASA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: EDN3_CANLF
Sequence: MEPGLWLLFGLTVTSAAGLVPCPQPGDAGKSGVPGTPPTARSEGDIQEPVAMTAVQGPSPRSPEQEQELGRFGEQASKGGPVHGRARRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGRRSTGLFPQSPQPSKWTQRCACVQSQDSACLHFCTRTLAVSRNSRTATNPDKEEEPASRGNGGLRPTR
What is the function of this protein?
Endothelins are endothelium-derived vasoconstrictor peptides.
What are the official names of this protein?
Endothelin-3, ET-3, Preproendothelin-3, PPET3.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSY1_BACHK
Sequence: MINSMQFLYLVASYLFGNILTAYIVTKWRHNVDIRDEGSGNPGARNMGRVYGKGYFVATFLGDAIKGAIVVSIAKYLFEDSTFLMLTLLAVIMGHIYPILFKGKGGKGISTFIGGLIAFDYLIALTLVTVFIIFYLIFKGFTKPGLITIACLPLCMILYSYSIVTTILSVLIIVLILYVNRE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 1, Acyl-PO4 G3P acyltransferase 1, Acyl-phosphate--glycerol-3-phosphate acyltransferase 1, G3P acyltransferase 1, GPAT 1, Lysophosphatidic acid synthase 1, LPA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL35_CHESB
Sequence: MPKMKTKSAVKKRFKVTATGRVKVQAAGKRHGMIKRSKKFIRNARGTMVLSDPDTKIVKQFMPYSF
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: LPXK_MANSM
Sequence: MKFWYTKSWIAYLLLPFSFLFWLVSQCRRWLFQAGIIKSYRAPVPIVIVGNLSVGGNGKTPVVIWLVKALQQNGLRVGVISRGYGSQSAVYPLLVTEKTDPLEGGDEPVLIAQRTQVPVCISANRQQAIELLLQTQPCDVIVSDDGLQHYKLQRDFEIVVVDAQRGFGNGFVMPAGPLRELPSRLDSVDLVIANGKANRYSQTVMTLAADYAVNLVTKEKRLLTEFESGSAFAGIGNPQRFFTMLQGFGIQLKQTYEFQDHQKFSAELFAKFSKNEPHFMTEKDAVKCFPFARENWWYVPVEAKITGQSAVNFIENIVERVKNGQ
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: AHPD_MYCTA
Sequence: MSIEKLKAALPEYAKDIKLNLSSITRSSVLDQEQLWGTLLASAAATRNPQVLADIGAEATDHLSAAARHAALGAAAIMGMNNVFYRGRGFLEGRYDDLRPGLRMNIIANPGIPKANFELWSFAVSAINGCSHCLVAHEHTLRTVGVDREAIFEALKAAAIVSGVAQALATIEALSPS
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: CAP3_ADEG1
Sequence: MTSSDTFLALAPYGRQEVADALSSLPDGKDARSLRHAPYANRLIKLQSAMVPPKVDGTSERVAEIVKGLAEQGAIYPDQMGAIHSDLLNRAYTWNSMGVQESIQALVNDVIHGQNRTLQDELARTKEIANASLLTQFFDSLYKTVDRGQRNFEGFKKLLRLFVNNVPNAEVYGSSGSFSVQINLGGSSQNINLTNAFENLKPIWGARWDAVNNPRIGALLTPNTRALLFFVSSFYDYGAMEPGSYLDNIMRLYKEAIRADVDAEGDAIMELGEAGANLNLRFNDYKDTLNYLLQNREVVPDTAPLELSAEQEMLLKYLMRQLRQALKDGVPADISISTMTQYLDPRLYQTNKVFVEKLQNYLLAAQARNPVYYRLLVLDPNWRPPAGLYTGNYVIPDRYDFEDVQSELEYAGPSRDEYFDDSLFAPGPQRRLNSAEEAQLERDIESLTGHIDEELGVQSQAGWLADHRLPVAFDGALSLTERNAYNTPLPPDSHMRSRSSSVASDLGLLNLSGTGGPGFFASLRPSIGSRQPTGTAVGLRPTTPYSGSGCMRGTGLARKVLNPAASRRGRKLRFY
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid exterior which mediates the interactions between the hexons, including the peripentonal hexons, and reaches all the way to the penton vertices.  Two hexon linking proteins IIIa, one from each facet, stabilize the unique edge interface between a pair of facets.  As the virus enters the host cell, hexon linking proteins IIIa are shed concomitant with virion acidification in the endosome.  During virus assembly, seems to play a role in the serotype specificity of the packaging of viral DNA via its interaction with packaging protein 3.
What are the official names of this protein?
Pre-hexon-linking protein IIIa, Capsid vertex-specific component IIIa, CVSC, Protein IIIa, pIIIa.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-linking protein IIIa family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Surrounds the border of each facet on the capsid exterior. Present in around 60 copies per virion.
Protein: TRIC_TRIVU
Sequence: MKLLLLSMGLALVCGLQPECSRSEEDLSDEKERKWEQLSRHWHTVVLASSDRSLIEEEGPFRNFIQNITVESGNLNGFFLTRKNGQCIPLYLTAFKTEEARQFKLNYYGTNDVYYGSSKPNEYAKFIFYNYHDGKVNVVANLFGRTPNLSNEIKKRFEEDFMNRGFRRENILDISEVDHC
What are the official names of this protein?
Trichosurin.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NS7_CVPFS
Sequence: MLVLLHAVFITVLTLLLLGRLQLLERLLLNHSFNLKTVADFNILYRSLAETRLLKVVLRLIFLVLLGFCCYRLLVILM
What is the function of this protein?
May function in the formation of membrane-bound replication complexes or in the assembly of the virus.
What are the official names of this protein?
Non-structural protein 7, ns7, 9 kDa hydrophobic protein, HP, Accessory protein 7, X3 protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns7/ns7a protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: KBX32_UROYA
Sequence: MQTQCTVLQLLVLVALCSCGGILKEKYFQKGVDYLTSHIPIPVVKDVVKSAAKQLVHKISKNQQLCLIVDTVQWCNKSCLAAENKEGYCHGTKCKCGIKVSY
What is the function of this protein?
Has antimicrobial activity against yeasts and bacteria.
What are the official names of this protein?
Antimicrobial peptide scorpine-like-2, SCl2.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 3 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: WECC_YERPE
Sequence: MSFETISVIGLGYIGLPTAAAFASRKKKVIGVDVNAHAVETINRGAIHIVEPDLDKVVKIAVEGGYLQAVTKPQAADAFLIAVPTPFKGDHEPDMIFVESAAKSIAPVLKKGDLVILESTSPVGATEQMAQWLAEARPDLSFPQQAGEAADINIAYCPERVLPGQVMVELIQNDRVIGGMTPKCSARASALYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICDEQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVSQNPQLARLIHTARLVNDGKPLWVVDRVKAAVADCLAASDKRASEVKIACFGLAFKPDIDDLRESPAVGVARLIAEWHVGETLVVEPNVEQLPKSLMGLVTLKDTATALQQADVLVMLVDHKQFKAIKPEDIKQQWIVDTKGVWR
What is the function of this protein?
Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
What are the official names of this protein?
UDP-N-acetyl-D-mannosamine dehydrogenase, UDP-ManNAc 6-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
Protein: AROQ_ERWT9
Sequence: MSDKLHVLLLNGPNLNLLGTREPEKYGHTSLDEIVSELTLQASALGVTLSHLQSNAEHALIDRIHQAKGNVDYIVINPAAFTHTSVALRDALLAVSIPFIEVHLSNVHAREPFRHHSYLSDISTGVICGLGVDGYSWALQTAVKRLSLSH
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: YAJQ_ECO55
Sequence: MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDASKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: FABB_BUCAI
Sequence: MRRVVITGIGIVSSIGNNKKEVLASLYKGVSGIVSSEEMKKLGMRSAVWGNIKLESINIITQKLSRFMNNASRYSFVAMMEAIKDAKIDREYYQKNPRVGLISGSGCSFSKNTLTSDIHLMKNKHISKGISPYLAVKTMPSGISACLSTLFKIYGVTYSISSACATSAHCIGNAFELIQFGRQDLIFAGGGEEISLELAMQFDAMRALSTCFNNDPKKASRVYDVYRDGFVISGGAGMLVIEELNSALSRSAYIYAEIIGYAATSDGSNIVVPSGDGAIRCMNLARKGKNIPIDYLNVHGTGTKIGDLIELEAIRKVFLNEKKPMISATKSMTGHGLGASGVHEMIYTLLMLKYNFIAPTINIENLEPCAENMNIIQKTTNIEINTAMSNSFGFGGTNVSLIVKKY
What is the function of this protein?
Involved in the type II fatty acid elongation cycle.  Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor.  Can also use unsaturated fatty acids.  Catalyzes a key reaction in unsaturated fatty acid (UFA) synthesis, the elongation of the cis-3-decenoyl-ACP produced by FabA.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] synthase 1, 3-oxoacyl-[acyl-carrier-protein] synthase I, Beta-ketoacyl-ACP synthase I, KAS I.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_STAAE
Sequence: MIGIIGAMEEEVTILKNKLTQLSEISVAHVKFYTGILKDREVVITQSGIGKVNAAISTTLLINKFKPDVIINTGSAGALDESLNVGDVLISDDVKYHDADATAFGYEYGQIPQMPVAFQSSKPLIEKVSQVVQQQQLTAKVGLIVSGDSFIGSVEQRQKIKKAFPNAMAVEMEATAIAQTCYQFNVPFVVVRAVSDLANGEAEMSFEAFLEKAAVSSSQTVEALVSQL
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: SYG_BORHD
Sequence: MIRIEDIISLAKRKGFVFQSSEVYGGLSGVWDYGPLGIELKQNIQKEWWKNMVYSHENVVGLDSSILMRSEVWTASGHVESFAELLVDCKNCKNRFKIDSIDFSKGCPNCNSMGTFTDPRSFDLMFKTNIGAVEDSSNEIYLRPETAQGIFVNFRNVLDSTRLKVPFGIAQVGKAFRNEIVAKNFIFRTCEFEQMEMQFFVHPNQMDDWYYYWQQKRLNFFIEILGIKSDNLRFKEHKGDELAHYAKAAIDIEYKFPFGFQEIEGIHNRGNYDLSQHAKFCGKPKLFEYHDLISGDRYIPYVIETSLGLTRSVLMTLCDAYAHEELEGGDKRIVLRLHPKIAPYKVAILPLVKKDGLPELARKVFMQFSDDFYMFYDDNGTIGKRYRRQDEIGTPYCVTVDYDSIENKTVTLRHRDTMTQVRIPINDLYSYVRTEILNYKGVSDR
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CVPA_ECOLI
Sequence: MVWIDYAIIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHYYTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGVCFGALRGVLIVAAILFFLDSFTGVSKSEDWSKSQLIPQFSFIIRCFFDYLQSSSSFLPRA
What is the function of this protein?
Required for colicin V production from plasmid IncFI ColV3-K30.
What are the official names of this protein?
Colicin V production protein, Protein DedE, Pur regulon 18 kDa protein.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEF_POLNS
Sequence: MALLTVLCYPDSRLHKVAKPVAQVDARIKKIVADMADTMYEAPGVGLAATQVDIHERIVVIDVSDEQNELMVFINPEIVWTSSETKSWREGCLSVPEFYDEVERPAEIRVKALDIDGKEFEIEADGSLAVCLQHELDHLQGKVFVEYLSIFKRTRISQKMKKRAKELIGQR
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: FTSB_SHIDS
Sequence: MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: OTOP1_MOUSE
Sequence: MPGGPGAPSSPAASSGSSRAAPSGIAACPLSPPPLARGSPQASGPRRGASVPQKLAETLSSQYGLNVFVAGLLFLLAWAVHATGVGKSDLLCVLTALMLLQLLWMLWYVGRSYMQRRLIRPKDTHAGARWLRGSITLFAFITVVLGCLKVAYFIGFSECLSATEGVFPVTHAVHTLLQVYFLWGHAKDIIMSFKTLERFGVIHSVFTNLLLWANSVLNESKHQLNEHKERLITLGFGNITIVLDDHTPQCNCTPPALCSALSHGIYYLYPFNIEYQILASTMLYVLWKNIGRRVDSSQHQKMQCRFDGVLVGSVLGLTVLAATIAVVVVYMIHIGRSKSKSESALIMFYLYAITVLLLMGAAGLVGSWIYRVDEKSLDESKNPARKLDVDLLVATGSGSWLLSWGSILAIACAETRPPYTWYNLPYSVLVIVEKYVQNIFIIESVHLEPEGVPEDVRTLRVVTVCSSEAAALAASTLGSQGMAQDGSPAVNGNLCLQQRCGKEDQESGWEGATGTTRCLDFLQGGMKRRLLRNITAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAAALFEVYCKI
What is the function of this protein?
Proton-selective channel that specifically transports protons into cells (PubMed:29371428).  Proton channel activity is only weakly-sensitive to voltage (PubMed:29371428).  Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes (PubMed:29371428).  In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration (PubMed:12651873).  Probably acts by maintaining the pH appropriate for formation of otoconia (PubMed:29371428).  Regulates purinergic control of intracellular calcium in vestibular supporting cells (PubMed:17606897, PubMed:20554841).  May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol (PubMed:29371428).  Also involved in energy metabolism, by reducing adipose tissue inflammation and protecting from obesity-induced metabolic dysfunction (PubMed:24379350).
What are the official names of this protein?
Proton channel OTOP1, Otopetrin-1.
What is the protein family that this protein belongs to?
Belongs to the otopetrin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Detected in the gelatinous membrane overlying the inner ear macular epithelium.
Protein: DESPB_DANRE
Sequence: MDMQVPSVCLLVPPPNPLAISLASKNSQYYEAILSVWNQLYINVKSMISWQYCLLDIGRINSLTMSMLSKMGPDESNNILRSLEMHFQEFKRHSQGSELFGAEDQKLIENQFAGAQQHFDKLVVDLPTYAARGEGSEYSAAVSVKMLNELNALRLKLDGAESSLISFLYIALGDDGLEECGQHISSTQAFQKNIQGLRGEFVSLRDGIQAELKDAGNSDKGRYLSGQLDIMNQRLLNLDNYFTTHLQRLDSVKSLLKDMMKAEDVVKVYEARLTEKETASSDPEEVQRYQKVLLSMRSDLEQKQDLLNSLVVDLNQMQKVNDQRDQGRYQCIINLTQYADHVHQLSDRWKRIHVQINNRLVDLDSYLPQLKRYMQSSSQLSGWIDETQKQIDSQHSVKMEDSAAYTQLLNQQKALNSDIKAKRELMETVHKDGETCISAIKNYELELATYSAGLETLLNIPIKRTVLQSPSSSIAEEVSSLNAHYLELLTRSSDYYKLLLASQKNMEELKIRNTRIELLEEELEQLRDAIKDQTANNASLQDALLQYQQELNNSQSHLLSLEEVKRTETMKCMATQESLDSSKDRLEELTEEVRRLKLQLEDMERKKKIVEERYTFLQEEHDETMRKKLKELEQASWAKMELEKTVSERNRELERLRKELEDEARRIKEAQTELAKVRQEHSTEIREVKQTYESQILVAQSSMQKLSQEKESDSAAMSLEFERLEGESSELKEQLKRLRISLSQEEAQRRILEEEVKRLTALNTEESRKRHELESQIQVMMSQKREGDNKMREVQESSSRTLQDKINEINRLTRNFEEERRLKRSLETDKRRLEGDLAVLKSKNETTNEELVQLRSSHRELSLIRVELEAHALEKGRSEQTIARLQARIQELQEELKRLEGELEKQRQVAEEEAGKRRRTESQLEKSSQAMREYTTTITTLRTSQEETNIGAKHADEKCKQLQEALDRASKENKVTSQNLAALKAEINTLKLQLTQEQGRVQDSNQRYEALHRSMEEKSCALNVSSGETERLQRLTETLTKDRQRVEEELRAVRLEHEELLKNKKRGDREMTEQITALQKQLDSSQRAGAEHDRLMRQLSREREKLQVEIENVQKQARETSSVIQTSQSQCSSLSQERDDLLKKITTMEQEIVRLKRLEDELARIKLSLESELRFKSQLQEENNKIKKDFTQWKTKCASHEEQLRQHASERSGLESQFSSVRTELERLRTQLREAEERYRLLLQNFEQERTEMQALRDSKQELLRLQQKPDGATKYTQTDQTDPSSLVFEGVRKNITAQQLQDCGVIDKVIFEQLMTGKRTVQDVSVDIRLNLKGTGAIAGLAAGPKGKMTFTEAKKQNLISDKSGNMLLEAQAATGYIIDPQANTKMTVEEACLNGVVDEADKKQLLIAEAACVGFRDPKTAKLLPVSQAMKKGIIDRETTLRLLQAQEAAGGILDPILSVYLPKDTAMDRDLVDEDLYQALNAKPDCYIDPDTDLRASYVTLKKQCKADLNTGLLLLPAPEKPITVQGLRSEVNVSDLVDAKLLEPSDMNHLREGKITSQEIEHRLRAYLRGSTCIAGIYDEAGECTLPIYQAMKNGLLRPGTTLELLEAQAASGFVIDPINNEYYTVEEACQKGLVGVEFKDKLLSAEKAVTGYKEPGTNKLISLFEAIERGLIEKGHGIRLLEAQIASGGIIDPKHSHRIDVDVAYQRGYFDQGMNQILKDEGDDTKGFFDPNTEDNLTYLELKSRCTIDKKTGLVLLPIHDKKKAQQKNSTRKRRVLIVDPDSNKEMTVREAYEKKLIDYETFLELSQQECEWEETTITAPDGSTSTAIMDMQTGIQYNLKELLAQGVIDQDVFNKYRSGGISVTELAGMITKKTKMLTNPVSSSSSSSLSSSSSSFTSQTTTKSQIVKTETIKSIESTSEYLQQDQSSANSSKHISSMSVKLSPLVESIEEQNPVGAIFDTEKLEKITVCDALKRGMIDSITAQRLLEAQACTGGIVSPDNGRRMSIQEATRVGVLDDEMANRIKPAQKAYIGFEDVKTKRKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLFDPELGCRRSLEEALQMGWLDMRAAQRLQDTRHHPKTLTCPKTKLRISYKEAMEACMNEENTGVRMLPAATVSSRGISSPYNLSNPGSASGSRSGSRRGSVDYSLSPSSSSRYSSFSYSRTSFSSRSLS
What is the function of this protein?
Involved in the organization of desmosome cell-cell junctions (PubMed:29522173).  Of particular importance in cell adhesion in the skin and during cardiac development (PubMed:29522173).  May also play a role in the regulation of Wnt, TGF-beta and Hippo signaling pathways (PubMed:29522173).
What are the official names of this protein?
Desmoplakin-B, Desmoplakin isoform X1.
What is the protein family that this protein belongs to?
Belongs to the plakin or cytolinker family.
Protein: LUXD_ALIF1
Sequence: MKDESSFFTIDHIIELENGQSIRVWETPPKSDTHKKNSTIVIAAGFARRMDHFAGLAEYLSSNGFRVIRYDSLHHVGLSSGQIDEFSMSIGKHSLLIVVGWLRAKGIQNLGIIAASLSARIAYEVINDIDASFLITAVGVVNLQDTLEKALKYDYLRLPIDELPDDLDFEGHNLGSKVFVTDCLKNEWDTLGSTFKAVQGLNIPFIAFTANGDSWVNQSDVEKMIDNIDTTQCKLYSLIGSSHDLGENLVVLRNFYESVTRAAVALDKGSLDLDIEIVEPGFEDLTSTTVKERRLRNKIENELLELA
What is the function of this protein?
Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction.
What are the official names of this protein?
Acyl transferase, ACT, C14ACP-TE, Myristoyl-ACP-specific thioesterase.
What is the protein family that this protein belongs to?
Belongs to the LuxD family.
Protein: MATK_GOSHI
Sequence: MEEFQVYLELNRSRRHDFLYPLIFREYIYALAHEHGLNKSMIFFENQGYGNKFSSLIVKRLILRMDQQNRLISSANDSNQNPVFGHNNNLYSQMIAVGFAVIVEIPFSLRLISYSQGAEVAKSHNLQSIHSIFPFLEDKFSHLNYVLEALIPHPIHLEILVQALRYWVKDASSLHLLRFSLYEYCNLKSFITPKKSISIFNPRLFLFLYNSHTCEYESIFLFLRNQSSHLRSTSSGVFLERIFFYGKIKYLGEVFYNDFQNNLWLFKDPFIHFIRYQGKSILASKDTSLLINKWKYYFVDLWQYYFYLWSQSGRVRINQLSKYSLDFLGYLSSVRLNPSVVRSQMLENSFLIDNAVKTLDTRIPIISLIGSLSKAKFCNTLGHPISKPTWADSPDSDIIDRFVRISRNLSHYHSGSSKKKSLYRIKYILRFSCVKTLARKHKSTVRAFLKKLGSEFLEEFFTETEEEHVFSLIFPRGFFAMRKVYRGRIWYLDIICINALVNHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.