PharMolix/UniProtQA huggingface dataset:
Protein: NU6C_CHAGL
Sequence: MLEQSAQITLFVLDFFIFVGALGVVFFNNIIYSALFLGLTFLSVALLYLLLGSEFLSVAQVIIYVGAINVLIVFAIMLVNKPEFDKKDMIWVPIDLKSFCVNFILFSTIVTMIVTTPWKLLVNNIDVKLNSLNFLSPIAKIGYQFLSTLVLPFELLSLLLLIALIGAVIIARRELIEDT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: COXX_BART1
Sequence: MSVSGELSVANGKSTPPKSSISDYIALLKPRVMSLVVFTALVGLMVSPVPINPWYGFLAIICIAVGGGGAGALNMWYDADIDAVMERTKKRPIPMGKISPPKAFIFGMVLSLLSVLVMGSFINWFAAFFLAFTIFFYVVIYTIWLKRITPQNIVIGGASGAFPPMIGWAVTTGAVSLDSFLLFLIIFMWTPPHFWALSLFSSLDYEAAGIPMMPNVRGEYSTKKQILFYTVLMVLCATAPCFTGLGGVFYGIFSTILGIIFIYFAYRLWKANTHDETILMAKKTFFFSLLYLAAVFGALLIESLVRYFIDL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APE2_AERPE
Sequence: MDQCLLEGYVAGIIDAEASLSVSIKIQEDLRCRVRVDPVFSITQDSKDVLNVVKNYFGCGRLMPKPGQEHLTLYVVDRLEALADCLIPKLDRLPLIVKKRGFEMFREIVLTLTRMKYRRVECCVIRDLVLKSYSLSSLNKKSKRKRSLEEILKIIPCDKAVEPPGER
What is the function of this protein?
Endonuclease involved in rRNA intron I-gamma homing.
What are the official names of this protein?
Homing endonuclease I-ApeII, rRNA intron-encoded homing endonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the LAGLIDADG endonuclease family.
Protein: VAPB3_MYCTU
Sequence: MLSRRTKTIVVCTLVCMARLNVYVPDELAERARARGLNVSALTQAAISAELENSATDAWLEGLEPRSTGARHDDVLGAIDAARDEFEA
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Upon expression in M. smegmatis neutralizes the effect of cognate toxin VapC3.
What are the official names of this protein?
Antitoxin VapB3.
Protein: RAVR2_HUMAN
Sequence: MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQRMQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAIQMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGSKVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQLCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQSSVMGNTSNLFLQNLSHIPLAQQQLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTTITAGMGMLPFFPNQHIAGQAGPGHSNTQEKQPATVGMAEGNFSGSQPYLQSFPNLAAGSLLVGHHKQQQSQPKGTEISSGAASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPASKTTLHKTGIASSILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISAPEGGSVECVDQHSQGTGAYYMETYLKKKRVY
What is the function of this protein?
May bind single-stranded nucleic acids.
What are the official names of this protein?
Ribonucleoprotein PTB-binding 2, Protein raver-2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=May shuttle between the nucleus and the cytoplasm.
Protein: SRP19_METB6
Sequence: MEKGECILYPCYFNAALSRAEGRRVPRNIAAKGPNANDVERALRRLGIACQAEEHHHPAHWARHEGRIIATYTGKKEALIKKVARAIEVRK
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_SHEB5
Sequence: MSGNKVEVDKRRTFAIISHPDAGKTTITEKVLLFGNALQKAGTVKGKKSGQHAKSDWMEMEKDRGISITTSVMQFPYGGALVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEERTIKLMEVTRLRDTPIVTFMNKLDRDIRDPIDLMDEVESVLNIACAPITWPIGSGKEFKGIYHILRDEVVLYQGGMGHTIQERRVIKGINNPDLEKAIGSYAADLRDEMELVRGASHEFDHAAFLKGELTPVFFGTALGNFGVDHILDGIVEWAPKPLPRESDTRVIMPDEEKFTGFVFKIQANMDPKHRDRVAFMRVCSGRYEQGMKMHHVRIGKDVNVSDALTFMAGDRERAEEAYPGDIIGLHNHGTIRIGDTFTQGEKFRFTGVPNFAPEMFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPIDTNDLIVGAVGVLQFEVVVGRLKSEYNVEAIYEGISVSTARWVYCKDERKLEEFRRKCSQNLALDGGDNLTYIAPTMVNLNLSMERYPDIEFAKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_BURMS
Sequence: MNAPHTPHLNEAEAAAAVEANAAELGRRALTRREQKEAYENNKLFKRLVRQVGQAIGDYNMIEHGDKVMVCLSGGKDSYALLDILLRLRERAPIDFDIVAVNLDQKQPGFPEHVLPEYLTKIGVPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVAGELGATKIALGHHRDDIVQTLLLNMFYGGKLKGMPPKLQSDDGKNIVIRPLAYAKETDLEKYAELREFPIIPCNLCGSQPNLKRAEMKALIRDWDKRFPGRVDNMFNALANVVPSHLMDARLFPFAGLRATGEADPNGDIAFDEDPCGTDASAPGGAKSVSIVQFDDL
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PI4KA_MOUSE
Sequence: MAAAGARGGGGGGGGGGGGGSGSSSGSSTSRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDCVVPYLLRLLRGLPKVYWVEESTARKGRGNLPVAESFSFCLVTLLSDVACRDPSLRDEILEAILQVLHVLLGMCQALEIQEKEYLCKYAIPCLIGISRSFGRYSNSEESLLSKLFPKVSPHSLRIPEELEGVRRRSFNDFRSILPSNLLTVCQEGTLKRKTSSVSSISQVSPERGIPPPSSPGGSAFHYFEASCLPDGTALEPEYYFSTISSSFSISPLFNGITYKEFCIPLEMLRELLNLVKKIVEEPVLKSLDAIVAGVMEANPSADLYYTTFSDPLYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNMSQGELQKILHDADRIHSEMSPLKLRCQANAACVDLMVWAVKDEQGAENLCIKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVIPSPVLVKLYKYHSQYHTVAGSDIKISVTNEHSESTLNVLPGKKNQPSMYEQLRDIAIDNICRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQEEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEAKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRSVLQYNSAMKNDTVTPAELSELRSTIINLLDPPPEVSALINKLDFAMSTYLLSVYRLEYMRVLRSTDPDRFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMAEKAKTKENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLSADIHKDQPYYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLTERPACVKKDYSNFMASLNLRNRYAGEVHGMIRFSGATGQMSDLNKMMVQDLITALDHSHPQHYTQAMFKLTAMLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKNGVEVPFMREMAGAWHMTVEQKFGLFSVETKEADPLAASEASQPRPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGGARGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNLDITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAAAKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLEQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLQCRSDAEDECFSQEADGKKICWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQNCFLSNRSRTYDMIQYYQNDIPY
What is the function of this protein?
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate.
What are the official names of this protein?
Phosphatidylinositol 4-kinase alpha, PI4-kinase alpha, PI4K-alpha, PtdIns-4-kinase alpha.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Localization to the plasma membrane is mediated by the PI4K complex and association with EFR3 (EFR3A or EFR3B), TTC7 (TTC7A or TTC7B) and FAM126 (FAM126A or FAM126B). Localization to the plasma membrane is regulated by TMEM150A.
Protein: UVRC_COXB1
Sequence: MTIDNPSAFLKTLPTGSGVYQMQDAQGKVIYVGKARNLQKRVSSYFRRQLDSKTQAMMAQVQSIQTTITRNENEALLLEASFIKQFRPRYNVLLRDDKSYPYLYLATHQKFPRLDFYRGAKKAPGRYFGPYPNAGSVRENLALIQKLFKLRQCSESFFKNRTRPCLQYQIKRCTAPCVGYVNEQEYRRQVEDAILFFEGKNDQVIIKLTERMEVASENLVFEEAAHYRDQIRQLRRLQKQQIITGGKGNIDIIGIAESNGAIGFAILFIRSGRMIGHKPFFPNTPLGTTLQTALVEFIPQYYLSPLRNGDIPERIVTSEPLEDRLWIQRALSSGLNRKLAITDQKRAPYKQWQAMAALNAAQALSQHLAQKNTFALKLEAIQKSLALPNPIARIECFDISHTLGEATVASCVVFGEEGPIKKDYRRFNISGVTPGDDYGALRQVLTRRYVRLKEGEGILPDVLLIDGGMGQLRQAAEVLEELQVSGVILTAIAKGPGRKAGLEKLFVWGRREEIHLPADNIAFHLIQQIRDEAHRFAITAHCNRRAKRRVESTLQEIEGIGPKRRQKLLKYFGGLQELQRASIEEIARVPGVSETLAKAIYDACHQHKG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_STRPC
Sequence: MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDMLAFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQADKSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTALRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTEIQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGLEKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGINAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMRLTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTDAMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMKRMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEGNGKAHRKY
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARC_ARTS2
Sequence: MMETPNNDSSRTPDEAAGAPDPESARYVANELSVADRQVNILRDKLRHIDRQLAAATQNNSKLVGMLETAKAEILRLKNALDQEGQPPYSFGTILQLNPKRQPTAGNSGQAATEESVDIFNAGRKMRVGVSPLVNMNQLAVGQEVLLNEALLVVAGLGYERAGELVTLKEMLGTDRALVVGRADEERVIRLSGALMSEKLRVGDALSIDSRTGYALEKVPRSEVENLVLEEVPDITYEDIGGLGPQIEQIRDAVELPFLHPDLYREHGLKAPKGILLYGPPGCGKTLIAKAVANSLAARAAERTGNVDLKSYFLNIKGPELLDKYVGETERHIRLIFSRAREKASDGSPVVVFFDEMDSLFRTRGTGISSDVETTIVPQLLSEIDGVERLDNVIVIGASNREDMIDPAILRPGRLDVKVKIQRPDAEAAADIFYKYITTDLPFHESDLAEHSGDVQATVDAMIQRTVEAMYSTEKSNEYLEVTYANGDTEMLYFKDFNSGAVVQNVVDRAKKYAIKDLLTTQQKGLRIDHLLRAVVDEFREHEDMPNTTNPDDWARISGKKGERITYIRTIVQGKAGQEPGKSIETMPSTGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: DAPA_PSEPW
Sequence: MIAGSMVALVTPMDAQGRLDWGSLGKLVDFHLENGTHAIVAVGTTGESATLSVEEHIEVIEFVVKRVAGRIPVIAGTGANSTSEAVHLTQNAKDAGADACLLVVPYYNKPTQEGLYLHFKHIAEAVDIPQILYNVPGRTSCDMQAETVIRLSTVPNIIGIKEATGDLARAKAILDGVSKDFIVMSGDDPTAVELILLGGKGNISVTANVAPREMADLCEAALEGNAEKARAINEKLMPLHKDLFCEANPIPVKYALVEMGLMQKGIRLPLTWLSEGCHEKVRTALRQSGVLV
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_STRR6
Sequence: MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKTRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVLPETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RS6_SHESR
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGVITEANGKIHRLEDWGRRQLAYPIQDLHKAHYVLMNVEAPAETIEELETAFRFNDAVLRNMVMRTKVAVTEASPMAKAKDERDSRRGPAGDRSYDEANAEEIAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y616_CHLTR
Sequence: MQYVMGRTNSMTRGFLNKRRVLEKCRTAKQKIHYCISRYFHYLPPVLAILLPIGSWPFLSEQQWWYGSFLFPVVSSLGWLFAIGRRERQLRAAAGQLLEAKIRKLTEQDEGLKNIRETIEKRQKETDRLKLHNDKLVEQLGQAREVFIQAKGRYDHMEELSRRLKEENQQLQIQLEAAVRERNEKILENQELLQELKETLAYQQELHDEYQATFVEQHSMLDKRQAYIGNLEAKVQDLMCELRNLLQLEMGAKTNLPGKPVASRDVVAQLVLEFRKIVFRVETTEAADSLTALRYTRTDPSAHNYSLACRQLFDGLREENLGMLFIYAPFAQRVLFANALFNDWTGYGLEDFLNRESDVVLEGFAQWERDLLTESRVERSGKIVIKTKAFGATPFYYCVVTLDKGPFAQHILGVLYPAKASFFTNLSYI
What are the official names of this protein?
UPF0242 protein CT_616.
What is the protein family that this protein belongs to?
Belongs to the UPF0242 family.
Protein: CD44_CANLF
Sequence: LAWGLCLLRLSLAQIDLNITCRYAGVFHVEKNGRYSISRTAAADLCKAFNSTLPTMAQMERALSVGFETCRYGFIEGHVVIPRIQPNAICAANHTGVYILISNTSQYDTYCFNASAPPEEDCTSVTHLPNAFDGPITITIVNRDGTRYSQKGEYRTNPEDINPSNPTDDDVSSGSSSERSTSAGYNIFHTHLPTAYPTEDQDSSRVSSNSDHTPITKDHDSSVHPSERSHTTHGSESAGHSSGSQEGGANTTSGPMRKPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINNGNGAVGDRKPSGINGEASKSQEMVHLVNKEPSETPDQYTTADETRNLQNVD
What is the function of this protein?
Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment.  Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection.  Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases.  Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion.
What are the official names of this protein?
CD44 antigen, Extracellular matrix receptor-III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, microvillus. Note=Colocalizes with actin in membrane protrusions at wounding edges. Co-localizes with RDX, EZR and MSN in microvilli.
Protein: FCG3B_HUMAN
Sequence: MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKDRKYFHHNSDFHIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFSPPGYQVSFCLVMVLLFAVDTGLYFSVKTNI
What is the function of this protein?
Receptor for the Fc region of immunoglobulins gamma.  Low affinity receptor.  Binds complexed or aggregated IgG and also monomeric IgG.  Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis.  May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
What are the official names of this protein?
Low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, CD16-I, Fc-gamma RIII, Fc-gamma RIIIb, FcRIII, FcRIIIb, FcR-10, IgG Fc receptor III-1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Secreted after cleavage.
Protein: KDSB_YERPB
Sequence: MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGTERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATIPWERERFAQSKETIGDCFLRHIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDLDRVRAIMLNQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDPA_DELAC
Sequence: MHAALSPLSQRFERIAVQPLTGVLGAEITGVDLREPLDDSTWNEILDAFHTYQVIYFPGQAITNEQHIAFSRRFGPVDPVPLLKSIEGYPEVQMIRREANESGRVIGDDWHTDSTFLDAPPAAVVMRAIDVPEHGGDTGFLSMYTAWETLSPTMQATIEGLNVVHSATRVFGSLYQAQNRRFSNTSVKVMDVDAGDRETVHPLVVTHPGSGRKGLYVNQVYCQRIEGMTDAESKPLLQFLYEHATRFDFTCRVRWKKDQVLVWDNLCTMHRAVPDYAGKFRYLTRTTVGGVRPAR
What is the function of this protein?
Involved in the degradation of the phenoxypropionate herbicides.  Catalyzes the enantiospecific cleavage of the ether bond in the herbicid R-dichlorprop ((R)-2-(2,4-dichlorophenoxy)propionate)(R-2,4-DP) and R-mecoprop ((R)-2-(4-chloro-2-methylphenoxy)propionate)(R-2,4-MCPP).  It can also accept (RS)-2-(2,4,5-trichlorophenoxy)propionate, (RS)-2-(4-chlorophenoxy)propionate, (RS)-2-(m-chlorophenoxy)propionate, however it can only accept 2-oxoglutarate as oxygen acceptor.
What are the official names of this protein?
(R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, RdpA, (R)-dichlorprop/(R)-mecoprop dioxygenase, Alpha-ketoglutarate-dependent dioxygenase, Dichlorprop/alpha-ketoglutarate-dioxygenase, Mecoprop/alpha-ketoglutarate-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the TfdA dioxygenase family.
Protein: GCSH_SYNJA
Sequence: MALEYPPHLRYVDTHEYIRVEDDIAVIGITAYAVDQLGDIVFVGLPEEGTEIEKGESFGSVESVKAVEDLYAPVSGKVVAVNKAVVDSPESIADDPYGDGWLIKVRMTNPEDLDDTMSAEAYASLVEGS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: GSTF1_ARATH
Sequence: MVTVKLYGMAYSTCTKRVYTTAKEIGVDVKIVPVDLMKGEHKEPAYLDNYHPFGVIPVLEDEDGTKIYESRAISRYLVAKYGKGSSLLPSPSDPKAYGLFEQAASVEYSSFDPPASSLAYERVFAGMRGLKTNEELAKKYVDTLNAKMDGYERILSKQKYLAGNDFTLADLFHLPYGAMVAQLEPTVLDSKPHVKAWWAASLRVIPGRLLRNSSKEFM
What is the function of this protein?
Specifically catalyzes the conjugation of synthetic 1-chloro-2,4-ditrobenzene to GSH.  Also functions as a glutathione peroxidase, converting linoleate oxidation products into their corresponding hydroxyacids.  This enzyme may thus serve to protect the cell from oxygen toxicity as well as from exogenous toxins such as herbicides.
What are the official names of this protein?
Glutathione S-transferase PM239X14, GST class-phi.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Phi family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RPT3_ARATH
Sequence: MMWESESDGGVGVGGGGGREYGDGVLSSNKHGGVKTDGFELRGQSWFVATDIPSDLLVKIGDMNFHLHKYPLLSRSGKMNRLIYESRDPDPTILILDDLPGGPEAFELASKFCYGVPVDLTATNISGLRCAAEYLEMTEDLEEGNLIFKTEAFLSYVVLSSWRDSILVLKSCEKLSPWAENLQIVRRCSESIAWKACSNPKGIRWAYTGKAPSPSTTNFAGSSPRWNESKDSSFYCSPSRNTNSQPVPPDWWFEDVSILRIDHFVRVITAIKVKGMRFELLGAVIMHYAGKWLPGLIKEGGVAIAPAMSSAIGGGLGLGGDEMSISCGSNSSGGSSGPDWKGGLHMVLSAGKTNGHQDSVACLAGLGISPKDQRMIVESLISIIPPQKDSVTCSFLLRLLRAANMLKVAPALITELEKRVGMQFEQATLQDLLIPGYNNKGETMYDVDLVQRLLEHFLVQEQTEGSSPSRMSPSPSQSMYADIPRGNNNNGGGGGGNNQNAKMRVARLVDSYLTEVARDRNLPLTKFQVLAEALPESARTCDDGLYRAIDSYLKAHPTLSEHERKRLCRVMDCQKLSMDACMHAAQNERLPLRVVVQVLFSEQVKISNALANTSLKESTTLGEAMGTYQPMIPNRKTLIEATPQSFQEGWAAAKKDINTLKFELETVKTKYVELQNEMEVMQRQFEKTGKVKNTPSSSAWTSGWKKLSKLTKMSGQESHDISSGGEQAGVDHPPPRKPRRWRNSIS
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Signal transducer of the phototropic response and photo-induced movements.  Involved in the phot1 pathway under low blue light (LBL) fluence rate and in the phot2 pathway under higher fluence rate of blue light (HBL).  Necessary for root and hypocotyl phototropisms, but not for the regulation of stomata opening.  Not involved in chloroplast accumulation and translocation.
What are the official names of this protein?
Root phototropism protein 3, BTB/POZ domain-containing protein RPT3, Non-phototropic hypocotyl protein 3.
What is the protein family that this protein belongs to?
Belongs to the NPH3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.