Protein: VERL_HALRU
Sequence: MSGMQWSFGFSCLFFLKTVWICQAFDADTPDPRVLSLDLTLVCSDDKSKQATLISYPVTFKGHVIKDMQIFCKNGWMQMTRGRGINMIRIHYPQTYTSVVPGACVFRGPYSVPTNDSIEMYNVSVALLWSDGTPTYESLECNVTKSQASNAPEPKASPTSSTPQPEAASHNQSKLIDWDVFCSQNENIPAKFISRLVAPKCLAVEKMDVDCSNGLVPITHEHGFNMMLIQYTRNKLLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTDLSIQCYMPKSPDAPKPESCLSSPPEPEASPSSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQDESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIQCYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPSSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHKFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAHKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLPIECYMPKSPVAPKPETGPSSNAPEPETYPTSSAPEKVYSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPQTYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPQTYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPQTYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPEASPTSNAPEPQTYPTSSAPGTSPEGSATAAPGTSPEGNTTAARNAYPRKSNQTTSTEDVLDDTSNYIIKVIPHCRTRGDVALIEIITDVDLSAVAVCSNGSRHHFNSTDFVHFYLPVSYNFTPSVCAFTRSKANLFKLHIGVSWKDRLHDVTTQKKDFLITCTFDPHKSHRGPTSASSEPLIAAKEIQSHQGPQSDAEEVFLKLVDIRNETLAAAVPLSKKVRLVGEVHGSSLESGLKPVACDAVGVQQGQRYTILRDGCGDGIVFAKDIGFITEGNKAFSPVFEVFKLHGNLHLTFMCNFTLCSHSCDGSSCSNQRRTRRSMAWQDIPHVADFDSSATPSTDMATVQVALLVAVALLITQLAGLAIYVNIN
What is the function of this protein?
Structural component of the egg vitelline envelope; forms long filaments.  Functions as species-specific receptor for the sperm protein lysin; prevents fertilization by sperm from other species.  Each VERL chain can bind multiple copies of the sperm protein lysin; this creates a 3 um hole in the egg vitelline envelope through which the sperm passes.
What are the official names of this protein?
Vitelline envelope sperm lysin receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Secreted, extracellular space, extracellular matrix.