PharMolix/UniProtQA huggingface dataset:
Protein: DUT_ANAMM
Sequence: MLKVKILRLASGYGLPLPSYATPKSAGLDLYAAVDSKLVVHPGGRCAVKTGVALELPDGYEAQIRSRSGLAANFGICVLNAPGTIDSDYRGEITVVLSNFGSEDYVISRGDRVAQMVIAPVERVEWEEVNSITATSRGEGGFGSTGT
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RS10_SACS2
Sequence: MPTKARIRLWSTNVENLNYVITQIRGIVEKTGIEMRGPIPLPTSKLEVPIMRLPHGEGRKKWEKWEMRVHKRLIDIAADERVMRQLMRVRVPEDVYIEIQLI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SURE_SHESH
Sequence: MIKILVSNDDGVTAPGIKALSDALSTSYQVMTVGPDRNCSGASNSLTLTNPLRINTLSNGYVSVSGTPTDCVHLAIRELYTDEPDMVVSGINAGANLGDDTLYSGTVAAAMEGRFLGLPAIAISLVGSTLTHYETAAHFACKVIAGLLKKPIAQDQILNINVPDLPIEQVKGIRVTRLGARHKAEGMIRTQDPAGRDIFWLGPPGDEQDASDGTDFHAVTNGYVSVTPLTVDLTAFEQISTMQQWIDKI
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTX56_ARATH
Sequence: MSETSKSESLDPEVSEGLCSKTLMQSIVHELKLQMRIGLPLVVMNLLWFGKMTTTSVFLGRQGELNLAGGSLGFSFANVTGFSVLYGISAAMEPICGQAFGAKNFKLLHKTLFMAVLLLLLISVPISFLWLNVHKILTGFGQREDISFIAKKYLLYLLPELPILSFLCPLKAYLSSQGVTLPIMFTTAAATSLHIPINIVLSKARGIEGVAMAVWITDFIVVILLTGYVIVVERMKENKWKQGGWLNQSAQDWLTLIKLSGPCCLTVCLEWWCYEILVLLTGRLPNPVQAVSILIIVFNFDYLLYAVMLSLGTCVATRVSNELGANNPKGAYRAAYTTLIVGIISGCIGALVMIAFRGFWGSLYTHHDQLILNGVKKMMLIMAVIEVVNFPLMVCGEIVRGTAKPSLGMYANLSGFYLLALPLGATLAFKAKQGLQGFLIGLFVGISLCLSILLIFIARIDWEKEAGKAQILTCNTEDEQTSQGSGQDSHS
What is the function of this protein?
Could function as a HCO(3)(-) -sensing component in the CO(2) signaling pathway in guard cells.  Acts as an upstream repressor of HT1.  Plays a role in stomatal response to CO(2).
What are the official names of this protein?
Protein DETOXIFICATION 56, AtDTX56, Multidrug and toxic compound extrusion protein 56, MATE protein 56, Protein RESISTANT TO HIGH CARBON DIOXIDE 1.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSB_MYCUA
Sequence: MTWPLPDRLSINSAISGSAVDLSSFAEFLRRQAPELLPASIKHGGGAVGDQLPHATTIVALKYPGGVLIAGDRRSTQGNMIAGRDVRKVYITDDYTATGIAGTAAIAVEFARLYAVELEHYEKLEGVPLTFAGKVNRLAIMVRGNLAAAMQGLVALPLLASYDIHASDPRSAGRIVSFDAAGGWNIEEEGYQAVGSGSIFAKSSIKKLYAQVTDADSALRVAVEALYDAADDDSATGGPDLVRGIYPTAVTINADGAVDVPEVRIAELAREVIGSRSRADTFGPDGGEK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_HELPG
Sequence: MEQSHQNLQSQFFIEHILQILPHRYPMLLIDRVVELEANRKIVAYKNITFNEDVFNGHFPNKPIFPGVLIVEGMAQTGGFLAFTSLWGFDPEIAKTKIVYFMTIDKVKFRIPVTPGDRLEYHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN2_BRAOL
Sequence: KSAVTRNYSEKKNERLWFKKNYDHAGNQRRIQKWNTQLK
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 2, Signalosome subunit 2, FUSCA protein 12, FUSCA12.
What is the protein family that this protein belongs to?
Belongs to the CSN2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL332_BACSU
Sequence: MRKKITLACKTCGNRNYTTMKSSASAAERLEVKKYCSTCNSHTAHLETK
What is the function of this protein?
Plays a role in sporulation at high temperatures.
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MNTH_ECOLC
Sequence: MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALNIWLLVGTALGL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CDPAS_METMA
Sequence: MIPAYLSNPFAAVFGGGKPIDGGRTYKDGRRILGDGKTYRGLFSGIFCGFLAGCVEVWLSFRGFEILGIEMPGFGPDYTSSLIVVLALASGALFGDMFKSFFKRRMGLKRGASLPLVDQLDFVVGAWVFTYLAAPEWFVSNFTPGIMLTVIIITPLLHLTTNIIGYFIGVKKEPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS5_BRUA4
Sequence: MAQRERNREDRGREERDSEFVDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATEAAKRDMIFVPLRSGRTLHHDVEGRHGAGKVLLRAAPAGKGIIAGGPMRAVFETLGVQDVVAKSLGSSNPYNMVRATFDALKHQMHPKDIAAQRGIKYSTLQARRHDVVGSEE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CDC37_SCHPO
Sequence: MAIDYSKWDKLELSDDSDIEVHPNVDKKSFIRWRQRDIHEKRAVRKQKMEDIKGAMAMNRRLLSRISEMETVLEKESPSDPYVLLGSFLEAKKSEDMDSAIPGGMSYHHMLMSLLKVIKDAEDTTEEKSMDDSDKCLRRLKSHKERLLKLLEDAQKEYDTLEAESKNYITSEDLHLGFDSTYVQKKEPEKPKKTKTKKETIQVIESLNNPTPPTDFPGAKEQASTGNAPKNPVNENESEDEEGLSLSEDGKKFANIDFGDYSSSEEFLKEHLNILADEEESDAILLEAFNAELEGKPSLAKQYVHQALLISYCRQLGPNGLSIFFQKIKDPNHQSQRLFLEDVHNTYVRIHERSAAISKEQAESGEGVEQIQLCAVDPNTKLSITIPEAGSTDPETQKARAAFESFPPNLQKALMTNDLDKINVVLGKMAVENAEEVVEKLSSTGMLSIEEGIIDTTKGETIPQLS
What is the function of this protein?
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
What are the official names of this protein?
Hsp90 co-chaperone Cdc37, Cell division control protein 37, Hsp90 chaperone protein kinase-targeting subunit.
What is the protein family that this protein belongs to?
Belongs to the CDC37 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=When in the nucleus associated with chromatin.
Protein: VIAA_YERPE
Sequence: MLSLATLDMLLSISEGELIEEMVVGLLAAPQLAIFFEKFPRIKRALMKDIPGWKQNLQQRIREASVPPGLANEFSLYQQSLLEDSPQFYAHLPDIVAQLQDLHSPFATQAKTLVQTADLAKNPPGGDSLQTLFLQRWRVSLILQTITIHHQLLEQEREQLLAELQRRLALSGALEPILTTNDNAAGRLWDMSQGHLQRGDYQLLLQYGDFLQQQPELIRLAEQLGRSRSAKAQPAPDARYEPYTVMVRQPDSVPEEVSGIHQSNDILRLLPTELVMLGMSELEFEFYRRLLERRLLTYRLQGDNWQEKTQQRPVSLKQNDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALLRIALADNRRCYIMLFATEIIHYELSADNGIEQAIRFLNQHFRGGTDLAACLANTLNKMEDREWYDADAVIISDFIAQRLPEELVRKIKIQQQAHQHRFHAVAMSAYGKPGIMRIFDHIWRFDTSLKSRLIRRWKR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: PK3CA_MOUSE
Sequence: MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFREARKYPLHQLLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
What is the function of this protein?
Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides.  Uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3).  PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology.  Participates in cellular signaling in response to various growth factors.  Involved in the activation of AKT1 upon stimulation by receptor tyrosine kinases ligands such as EGF, insulin, IGF1, VEGFA and PDGF.  Involved in signaling via insulin-receptor substrate (IRS) proteins.  Essential in endothelial cell migration during vascular development through VEGFA signaling, possibly by regulating RhoA activity.  Required for lymphatic vasculature development, possibly by binding to RAS and by activation by EGF and FGF2, but not by PDGF.  Regulates invadopodia formation through the PDPK1-AKT1 pathway.  Participates in cardiomyogenesis in embryonic stem cells through a AKT1 pathway.  Participates in vasculogenesis in embryonic stem cells through PDK1 and protein kinase C pathway.  Also has serine-protein kinase activity: phosphorylates PIK3R1 (p85alpha regulatory subunit), EIF4EBP1 and HRAS.  Plays a role in the positive regulation of phagocytosis and pinocytosis (PubMed:19604150).
What are the official names of this protein?
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, PI3-kinase subunit alpha, PI3K-alpha, PI3Kalpha, PtdIns-3-kinase subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, PtdIns-3-kinase subunit p110-alpha, p110alpha, Phosphoinositide-3-kinase catalytic alpha polypeptide, Serine/threonine protein kinase PIK3CA.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
Protein: DER_RICAE
Sequence: MTKQIITLVGRPNVGKSTLFNRLSIRKKAIVHDLPGVTRDRKYTDGKIGSFEFLLIDTPGLDEHPNSMGERLIEQTTKAILEADLICFMVDGRSGILPDDKLLSSFVRKYNKPAILVVNKCEKAFDFDKEYYKLGFDSMIAISAEHGTGLIDLYDEIIAKLPEEESIKTNIADPIKGDCLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKNNHIKLIDTAGLRKKSTITKSLEKLSASDTINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRSIVIVVNKWDLVKESEKEAFQEEFYYQINTHLPQVKGIPVLFISAINKQNIEQVLDACLKIYKIWNKKITTSKLNEWLNFTTEAHLLPLQKGGRRVRVKYMTQTKTRPPTFKLFSNNPEKITDSYTRYLVNNMREAFDMPGVPIRFIYVKTKNPYV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ADAP2_HUMAN
Sequence: MGDRERNKKRLLELLRAPDTGNAHCADCGAADPDWASYKLGIFICLNCCGVHRNFPDISRVKSVRLDFWDDSIVEFMIHNGNLRVKAKFEARVPAFYYIPQANDCLVLKEQWIRAKYERREFMADGETISLPGNREGFLWKRGRDNSQFLRRKFVLLAREGLLKYFTKEQGKSPKAVISIKDLNATFQTEKIGHPHGLQITYRRDGHTRNLFVYHESGKEIVDWFNALRAARLQYLKMAFPELPESELVPFLTRNYLKQGFMEKTGPKQKEPFKKRWFALDCHERRLLYYKNPLDAFEQGQVFLGNKEQGYEAYEDLPKGIRGNRWKAGLTIVTPERRFVLTCPSEKEQQEWLESLRGVLSSPLTPLNRLTASTESGRSSR
What is the function of this protein?
GTPase-activating protein for the ADP ribosylation factor family (Potential).  Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).  Possesses a stoichiometry of two binding sites for InsP4 with identical affinity.
What are the official names of this protein?
Arf-GAP with dual PH domain-containing protein 2, Centaurin-alpha-2, Cnt-a2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Constitutively associated with the plasma membrane. Excluded from the nucleus.
Protein: EPMA_ECOLU
Sequence: MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: SPC25_CANAL
Sequence: MDTAERAYEKFQNQMIAFDNLKIEMNELAVDLDQQLSDKQSLILQQEQDHKQKVNDLTNQEYKLKLQAKSLKEKENATRDKLNLAMRSLEQQKSKVEDLVKKKQSLVDTKQDLESQIKQLETAIDQGTRELNKSNDNMSLQMNKNLVELNKYEIYTGLKIEVQSNELMCFKFFNLDPNDYDREFAITLNIGGSTYSIENTSPKLSDETVEQIQGKLNQGRQLSKFLKEVRTLFKDFVQY
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein SPC25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: SYV_BACLD
Sequence: MDNQELTMPTKYDPSAVEKDRYDYWVNGKFFEAKNDPEKEPYTVVIPPPNVTGKLHLGHAWDSTLQDIVTRMKRMQGYDVLWLPGMDHAGIATQAKVEAKLREEGKTRYDLGREKFLEETWNWKEEYADFIRSQWAKLGLGLDYSRERFTLDEGLSKAVREVFVKLYEKGLIYRGEYIINWDPATKTALSDIEVIYKDVQGAFYHMRYPLKDGSGSIEIATTRPETMLGDTAVAVHPEDERYKHLIGKTVILPITGREIPIVGDDYVDMEFGSGAVKITPAHDPNDFEIGNRHNLERILVMNEDGTMNDNALQYKGMDRFECRKQIVKDLQEEGVLFKIEEHTHSVGHSERSGAVVEPYLSTQWFVQMQPLADAAIELQKSEGKVNFVPDRFEKTYLHWMENIRDWCISRQLWWGHRIPAWYHKETGEIYVGVEAPEDAENWEQDKDVLDTWFSSALWPFSTMGWPDIDEEDFKRYYPTNVLVTGYDIIFFWVSRMIFQGIEFTGERPFKDVLIHGLIRDDQGRKMSKSLGNGVDPMDVIDKYGADSLRYFLATGSSPGQDLRFSFEKVESTWNFANKIWNASRFALMNMDGMTYEELDLSGEKSVADKWILTRLNETIETVTQLADKYEFGEVGRHLYNFIWDDFCDWYIEMAKLPLYGEDEAAKKTTRSILAYVLDQTMRLLHPFMPFLTEEIWQHLPHEGESITVAKWPEAVKEYTDTEAAADMKLLVEVIRAVRNIRSEVNTPLSKQIELYIKTSTPEIAERLEENRSYVERFTNPSLLQIGTDIQAVDKAMTAVVSGAELILPLEGLINIDEEISRLQKELDKLTKEVERVQKKLSNEGFMKKAPAHVIEEERAKEADYTAKREAVEKRIAELKN
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENG_STAAM
Sequence: MADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKDMGVRKGTKALDVCCGTGDWTIALSKAVGPTGEVTGIDFSENMLEVGKEKTASMENVKLVHGDAMELPFEDNSFDYVTIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLPVFKQMYALYFKFVMPIFGKLFAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRVRSFTGGVAAMHLGYKEKDNTKGD
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SURE_HAEIG
Sequence: MRILVSNDDGFHAEGIQVLATELRKIAEVIVVAPDRNRSAASSSLTLVEPLRPRHLDNGDYCVNGTPADCVYLALNGFLSGQVDLVVSGINAGCNMGDDTIYSGTLAAALEGRHLGLPAIAVSLDGRQHYETAARVVCDLIPKLHHQLLNPREIININVPDLPFEELKGYKVCRLGYRASSAEVIKQKDPRDETIYWIGPSALPEDESEGTDFYAVKNGYVSITPIQADLTAYHSLLSLQNWLEQEFTK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3B_MYCPN
Sequence: MKVLINKNELNKILKKLNNVIVSNNKMKPYHSYLLIEATEKEINFYANNEYFSAKCTLAENIDVLEEGEVIVKGKIFSELINGIKEDIITIQEKDQTLLVKTKKTNINLNTIDKKEFPRIRFNQNVDLKEFDELKIQHSLLTKGLKKIAHAVSTFRESTRKFNGVNFNGSNGKQIFLEASDSYKLSVYEIKQKTDPFNFIVETNLLSFINSFNPEGGDLISIFFRKEHKDDLSTELLIKLDNFLINYTSINESFPRVMQLFDFEPETKVTIQKNELKDALQRILTLAQNERFFLCDMQVTNSHLKINSNVQNIGASLEEVTCLKFEGHKLNIAVNALSLLEHIDSFDTDEIELYFQGSNKYFLISSNNEPELKEILVPSK
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAA50_DANRE
Sequence: MKGRIELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVLEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYQKFGFEIIETKKNYYKRIEPADAHVLQKSLRSPCAPPAGELQKAD
What is the function of this protein?
N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine (By similarity).  Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position (By similarity).  Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins (By similarity).  The relevance of N-epsilon-acetyltransferase activity is however unclear (By similarity).  Required for sister chromatid cohesion during mitosis by promoting binding of CDCA5/sororin to cohesin (By similarity).  Essential in embryonic cell proliferation and survival (PubMed:16484612).
What are the official names of this protein?
N-alpha-acetyltransferase 50, N-acetyltransferase NAT13, N-epsilon-acetyltransferase 50, NatE catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the cytoplasm in interphase cells.
Protein: FAM91_DICDI
Sequence: MDQSSEKELEKYINNRVQWDSLPSHAKSILDQSHVKYKQYCLKYSIKHQLRWDTNLISSFVTDERLYYQEIVRLSVANLVLYPYHIQDKLVPMLNVTPFKYYLIMMIETMTNSKSYDEIPNFTAVDCIRVLGIGRNQFIDLMNKFRSKGFLFKKKKDVIRGLLPTRSLEKNIEYWWILRYGYPNQDEERQGSLPASELEVLDDLKRSNGINGKQAGIYCRESVISLISKGLVYIDVPIQNQDTISVPPLEGFVMNRVLGDYFENLLYKIFVSIDERTTIQKLSEVLQINVELVKQACSLYCRLGFAKKKNLEPLLPQTPSPSSEGDTHSKWHHSWITYYQENETIIPQPILNNNNNNSNTIDNSNNNNNNNTNITSSSSSNTAINNSSQSSTLENNDNIVEGVVDESFNNGNEEQKRIGFVFDSSITAFLMMGNLGYGLKNHAVTMFERGKLSNEALADFLQELDKIDVEEFVDSEAKLYATNAISLRDTIRHLKNKYRIDDSNSSNSNSSSGGGSGNLQGLDLISCERMNQLDETTRIRVLKKNYSVLISMAPLSIDYCPVISSVPPNFGPAVYEVHSFWFRIYLYSMVGKGPNSILLPKGTRLKRIPTIFKDCEKILVCPIDHDPTTVNLSQLLPSVNETLLSSPVLLSAYTFIKYDTQPKLSKLMSHSRSNSIVSSSKDNQLLYHIPFPLDDLSADNGSPKKYTNIITNNTTTTTTTTTTTNTTNLNNNTIISEDQYNSDNIHTHPILYKIQSTFNLKNSFGYITLLKKETHILLNNNNNNNNKNNINNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNSITHQKVFEYLPLNVYYGIPIFDDKLNREVCAKIDKFNLLSKENLNRHSMDSRNLSLNLFNFISSTCPPIHPDLDSIDATKINSNLPSVQNIPFPTQIITFVNGNLDL
What are the official names of this protein?
Protein FAM91 homolog.
What is the protein family that this protein belongs to?
Belongs to the FAM91 family.
Protein: HDEA_SHIFL
Sequence: MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLAVDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKQANFKDKVKGEWDKIKKDM
What is the function of this protein?
Required for optimal acid stress protection.  Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins.
What are the official names of this protein?
Acid stress chaperone HdeA.
What is the protein family that this protein belongs to?
Belongs to the HdeA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YOG6_CAEEL
Sequence: MSLLKKCIGLDPNIRKPLDIGLIWEGNYWDDKDVHDCCDVDWETCEILVRKIAKALVLPTSPIDNGGIENKKILIFLPKVMQLPLTILAAYRVGLIGIVMDPLVSKNKVLEKIIMCEKPRIVVTVDAVWQAQELIEIKSKVEVRSIYEY
What are the official names of this protein?
Uncharacterized protein ZK112.6.