PharMolix/UniProtQA huggingface dataset:
Protein: QACF_KLEAE
Sequence: MKNWIFLAVSIFGEVIATSALKSSHGFTRLVPSVVVVAGYGLAFYFLSLALKSIPVGIAYAVWAGLGIVLVAAIAWIFHGQKLDFWAFIGMGLIVSGVAVLNLLSKVSAH
What is the function of this protein?
Multidrug exporter.  Is implicated for the resistance to bacteriocidal quaternary ammonium compounds.
What are the official names of this protein?
Quaternary ammonium compound-resistance protein QacF, Quaternary ammonium determinant F.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MDTH_SALPK
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCFLSGLGGTLFDPPRSALVVKLIRPEQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAILFILCALFNAWLLPAWKLSTVRTPVREGMRRVMSDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDIAGSPAAVKWMYAIEACLSLTLLYPIARWSEKRFRLEHRLMAGLLVMSLSMLPIGMVGNLQQLFTLICAFYIGSVIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDMGKALAQPELPWMMLGIIGFITFLALGWQFSHKRTPRRMLEPGA
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NODI_SINFN
Sequence: MQLLTRANVSSSPSRRPESNALKQKCHGHSNADNSLSRSKSDVAIELTNVSKSYGDKVVVDQLSFTITSGECFGLLGPNGAGKSTVSRLVLGLAPPDEGTITVLGEPVPARARLARSRIGVVPQFDTLDREFTARENLLVFGRYFGLHTRELEEAIPPLLDFARLESKADVPVAQLSGGMQRRLTLACALINDPQLLILDEPTTGLDPHARHLIWERLRSLLALGKTILLTTHFMEEADRLCDRLCVIEHGRKIVEGRPHALIDEQIGCDVIEIYGGNPRELTSVVGPYAQRVEVSGETLFCYSSDPEQVRLQLRGRTGLRLLQRPPNLEDVFLRLTGREMKD
What is the function of this protein?
Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction.  Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide.  This subunit is responsible for energy coupling to the transport system.
What are the official names of this protein?
Nod factor export ATP-binding protein I, Nodulation ATP-binding protein I.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipooligosaccharide exporter (TC 3.A.1.102) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IFT56_RAT
Sequence: MMLSRAKPAVGGESPHTDKRKKKGRKIPKLEDLLSQRDFTGAITLLEFKRHVGEQEEDTNLWIGYCAFHLGDYKRALEEYENAAKEENCNPEVWVNLACTYFFLGMYKQAEAAGFKAPKSRLQNRLLFHLAHKFNDEKKLMNFHQNLQDIKEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGKAAEAELKSLMDNASSPFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEVFLLIQSEKLKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMILAGREPKETLREVLHLLRSTGNTQVEYIIRIMKKWAKENRVPI
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium.  Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly.  Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU.  Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components.  Not required for IFT complex A ciliary localization or function.  Essential for maintaining proper microtubule organization within the ciliary axoneme.
What are the official names of this protein?
Intraflagellar transport protein 56, Tetratricopeptide repeat protein 26, TPR repeat protein 26.
What is the protein family that this protein belongs to?
Belongs to the IFT56 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Localizes at the transition zone in photoreceptor cells.
Protein: COAX_DESVV
Sequence: MARHLLLFDIGNTNVKVGIATEGTVLTSYALPTDGTQTGDGFGLALLDIMRHAGLGADDIDACVGSSVVPSLDPLLRHACERFLWRPLQLAHVDLPVPLENRYERPTEVGADRLVAAFAARRLYPDARALVSVDFGTATTFDCVDGDAYLGGLICPGVLSSAGALSSRTAKLPRVSLEVSEDMPVVGRSTTTSLNHGFIFGFAALAEGVTARLRKVLPEPLEVVATGGFARAVARVSDCFDHVRPDLLLEGLRLLYLESEQR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_TREDE
Sequence: MKIMMVTSELVPFAKVGGLADAVTALSIALAEKRHDVRVVMPRYYKIDRKNLKQIPGAMAVHLGPYEHWVGVYESNLPSSKVKVYFIDHEQAFGRDGVYGSAFEPDFSDNTKRFSLLAHAAFQVCRKQAWIPDVVHAHDWAAGLVPVLLRFTEKNTEFKNTASVFTIHNMGYQGVYSKHTFPDTGLDWNDFYTTGFEDWDRINFLKAALVSSDMLTTVSPSYAEEIKRPEFGFRMDGILRYREKELTGILNGVDTSIWNPSKDEYIPYRYNSKTLEEKEKNKSVLQERFGLEIDISVPVFGMISRLVDQKGISELFGPMYGSAFKICSDIKLQMVVLGSGESWCEKELNFLSQRLPNFRCYIGYNEELSHLIEAGSDFFLMPSRYEPCGLNQMYSLLYGTLPIVRKTGGLADTVENYNEETGEGTGFVLDYLSPQSIYDTVGWAAYAWYNKKDHIKKMRTKAMSKKFGWNIAAEKYLKVYADAIEKKASML
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: SERC_XYLFT
Sequence: MTMRIFNFSPGPATLPEPVLRQAQAEMLEWNAVGASVMEISHRSAEFIALAKGIESDLRCLLGVPDDYAVLFLSGGATTQQALLPLNFAAPGQTADYVVTGHWSKTALKQASPYVNINVVADGERDGFQDIPNRAGWRLSKDAAYVHMTANETIHGVEFRQTPDVGDVPLFADFSSSIAADLIDVSKYDLIYAGAQKNLGPVGICVVIVRRTLLERTGQPRADIFTYASHAERDSMLNTPPTFNWYLLGLTVKWMLAEGGVQEFARRNQAKAQLVYQTIDQSGGFYRNGVAAAVRSRMNIPFFLPNVEQDARFAAEAKAAGLLSLKGHKAVGGIRASLYNAMPLAGVQALVAFMHDFQQRYG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPB_SALPK
Sequence: MRNYDLSPLLRQWIGFDKLANALQNSGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLDIQLEGTRLTVKGTPEQPENEPKWLHQGLVMQPFSLSFTLAENMEVSGATFTNGLLHIDLTRNEPETIAPQRIAINERSALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRR_STAAS
Sequence: MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLIALVVYIVHSYNSGVEYAKKHAKDVKVHQFNGPVKNDGKISILVLGADKAQGGQSRTDSIMVVQYDFINKKMKMMSVMRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINPEYYAVVDFTGFEKMIDELMPEGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFRHDPEGDFGRVRRQQQVMQTLKKEMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGLSFGIRGEKDVKSLTVPIKNSYEDVNTNTDGSALQINKNTNKQAIKDFLDED
What is the function of this protein?
Involved in SarA attenuation.  Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors (By similarity).
What are the official names of this protein?
Regulatory protein MsrR.
What is the protein family that this protein belongs to?
Belongs to the LytR/CpsA/Psr (LCP) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: GUAA_STAAN
Sequence: MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: DRE2_DROME
Sequence: MENFKGLQKSLYIWTDSADLDKRVEQLKAATGGDVALENVHRLSFSSYANSSFDLIVIECAQLTDSYVKLLHMLKPSGKLHLVSYIGPAASLLQEIKLSGFINCREDSPDALTAEKPGYETGSSARLSFAKKNASAVNVWKISGDDEELIDEEELLDEEDKQKPDPAGLRVCSTTGKRKACKNCSCGLAEELETEKQSQKATENAKSSCGNCYLGDAFRCSTCPYLGMPAFKPGEKVQLADNLLKSDI
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: FTSK_STRP1
Sequence: MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNIGSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDETSLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKIGVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQTEADYDDAFDPGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQTN
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the difSL recombination site, which is located within the replication terminus region.  Required for activation of the XerS recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: NODD1_BRAJP
Sequence: MRFKGLDLNLLVALDALMTERKLTAAARSINLSQPAMSAAITRLRTYFRDELFTMNGRELVPTPRAEALAPAVREALLHIHLSIISWDPFNPAQSDRSFRIILSDFMTLMFFERVVVRVAREAPAVSFELLPFSDEPDELLRRGDVDFLILPEMFMSHTHPRAKLFDERFVCVSCPTNQKLPPQLSIDNYVSMGHVAAQFGKQRPSVEEWLLREHGLRRRVEVAVPGFTMIPPFLSGTDRIATLPLRLAMHFAKAIPLRITELPQPIFPAFTEAVQWPAPHSSDPASLWMREIFLQEASRVEFQSETSAHALSSSQLPTCL
What is the function of this protein?
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins.  NodD is also a negative regulator of its own expression.  Binds flavonoids as inducers.
What are the official names of this protein?
Nodulation protein D 1.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: ATPG_ECOBW
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRPD_PSEE4
Sequence: MDIKSALSRIVGHLDLSTEEMRDVMRQIMTGQCSEAQIGAFLMGMRMKSESIDEIVGAVSVMRELADKVELKSLDGVVDIVGTGGDGANIFNVSTASAFVIAAAGCTVAKHGNRAVSGKSGSADLLEAAGIYLNLTPVQVARCIDSLGIGFMFAQTHHSAMKHAAGPRRDLGLRTLFNMLGPLTNPAGVKHQVVGVFTQALCRPLAEVLQRLGSKHVLVVHSKDGLDEFSLAAPTFVAELKNDQITEYWVEPEDLGMKSQSLHGLAVEGPQASLELIRDALGRRKTENGQKAAEMIVLNAGAALYAADHAMTLAQGVELAHDVLHTGLAWEKLQELGAFTAVFKVENEA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: NUSB_BIFLO
Sequence: MARSTARKRALNTLYEADEKSQDILSLLDERIAHPGAQTPLPDYAIEIVKGVAEHRRQIDMTLDEHSTGWKVRRMGVVDRNILRIAAWEILFTDDVPDKVAIDEALALAKTLCDDDSPAFIHGLLSAVCTAKNAAPAPESVAEEADEESSDSAAAASEPTDEGDVSDSPDSSGASDEPAAPSAEIQPTVD
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: SUCC_TRIL1
Sequence: MNIHEYQAKEILSTYGIPVPRNRVALTADQVERAAKMMGGHCVVKAQIYAGGRGKAGGVKLVHHPEQASDVAKELFGKRLVTKQTGPEGLKVRRILVEETVEIAREFYLSITLDRETSRYCLIASAEGGMDIEEVAQKSPDKIHVLTIDPFTGLRTYQARKIALALGLSGAVCEDCVELILNTYKCCLEKDCSLIEINPLVVTRAGWLLAMDAKISFDDNAVYRHREYPDMVDYSQLDPLEITAGKYDLAYIKLTGNIGCMVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEAFKIILQDSDVKAVFVNIFGGIMRCDVIAQGIIEAANEVHCPLPIVVRMDGSNVEDGKKLLLESGLNVQIGDNLGDGAQKIVAMLAKA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: Y3126_MYCTU
Sequence: MVIRFDQIGSLVLSMKSLASLSFQRCLRENSSLVAALDRLDAAVDELSALSFDALTTPERDRARRDRDHHPWSRSRSQLSPRMAHGAVHQCQWPKAVWAVIDNP
What are the official names of this protein?
Uncharacterized protein Rv3126c.
Protein: CNO11_DANRE
Sequence: MTLAPKDLSNLLGIMSEDACSSSFEQLSSAFHHCFGKAEHFGVGSVLVMLLQQPDLLPSAPQRLTALYLLWEMYRTEPLAANPFAAVFAHLLNPSSAAEEQEKTLSGFLPPITLPEKFFLSQLMLAPPRELFKKTPRQVSCMDITSTPQTIDISGLQLALAERQSELPTQSKASFPSLLSDPDPDSSNSGFDSSVANQITESLVTGPRPPLESHFRPEFIRPTPPLLVCEDELCWLNPCEPEHRVQWDRSMCVRNGTGVEIKRIMAKAFKSPLSAAQQTQLLGELEKDLKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMSSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDNGETPAEGKTSK
What is the function of this protein?
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Is required for the association of cnot10 with the CCR4-NOT complex.  Seems not to be required for complex deadenylase function (By similarity).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 11.
What is the protein family that this protein belongs to?
Belongs to the CNOT11 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YBET_ECOLI
Sequence: MNKKLMYIFAIFIVAAITCISQPKKTTLRDKAMVNYAFDYLSSPGSLPFTTAATELSAIHGHSTSQYRLGEFYLHGSDGKPLDYTQARYWYEQSAEQENPRAQSKLGWIYLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQKWLKLTAKQHYKNAERLLAGLPAH
What are the official names of this protein?
Sel1-repeat-containing protein YbeT.
What is the protein family that this protein belongs to?
To E.coli YbeQ.
Protein: BNR1_YEAST
Sequence: MDSSPNKKTYRYPRRSLSLHARDRVSEARKLEELNLNDGLVAAGLQLVGVALEKQGTGSHIYMKQKNFSANDVSSSPMVSEEVNGSEMDFNPKCMPQDASLVERMFDELLKDGTFFWGAAYKNLQNISLRRKWLLICKIRSSNHWGKKKVTSSTTYSTHLATNELAENAHFLDGLVRNLSTGGMKLSKALYKLEKFLRKQSFLQLFLKDEIYLTTLIEKTLPLISKELQFVYLRCFKILMNNPLARIRALHSEPLIRWFTELLTDQNSNLKCQLLSMELLLLLTYVEGSTGCELIWDQLSILFTDWLEWFDKILADDIAIHSSLYLNWNQLKIDYSTTFLLLINSILQGFNNKTALEILNFLKKNNIHNTITFLELAYKDDPNSVVIMEQIKQFKSKESAIFDSMIKTTNDTNSLHPTKDIARIESEPLCLENCLLLKAKDSPVEAPINEIIQSLWKILDSQKPYSESIKLLKLINSLLFYLIDSFQVSTNPSFDETLESAENVDYVFQDSVNKLLDSLQSDEIARRAVTEIDDLNAKISHLNEKLNLVENHDKDHLIAKLDESESLISLKTKEIENLKLQLKATKKRLDQITTHQRLYDQPPSLASSNLSIAGSIIKNNSHGNIIFQNLAKKQQQQQKISLPKRSTSLLKSKRVTSLSSYLTDANNENESQNESEDKSKDSLFQRSTSTINFNIPSMKNITNMQNVSLNSILSELEFSNSLGTQPNYQSSPVLSSVSSSPKLFPRLSSDSLDNGIQLVPEVVKLPQLPPPPPPPPPPPLPQSLLTEAEAKPDGVSCIAAPAPPPLPDLFKTKTCGAVPPPPPPPPLPESLSMNKGPSNHDLVTPPAPPLPNGLLSSSSVSINPTTTDLKPPPTEKRLKQIHWDKVEDIKDTLWEDTFQRQETIKELQTDGIFSQIEDIFKMKSPTKIANKRNAESSIALSSNNGKSSNELKKISFLSRDLAQQFGINLHMFSQLSDMEFVMKVLNCDNDIVQNVNILKFFCKEELVNIPKSMLNKYEPYSQGKDGKAVSDLQRADRIFLELCINLRFYWNARSKSLLTLSTYERDYYDLIFKLQKIDDAISHLNRSPKFKSLMFIITEIGNHMNKRIVKGIKLKSLTKLAFVRSSIDQNVSFLHFIEKVIRIKYPDIYGFVDDLKNIEDLGKISLEHVESECHEFHKKIEDLVTQFQVGKLSKEENLDPRDQIIKKVKFKINRAKTKSELLIGQCKLTLIDLNKLMKYYGEDPKDKESKNEFFQPFIEFLAMFKKCAKENIEKEEMERVYEQRKSLLDMRTSSNKKSNGSDENDGEKVNRDAVDLLISKLREVKKDPEPLRRRKSTKLNEIAINVHEGDVKTRKDEDHVLLERTHAMLNDIQNI
What is the function of this protein?
May organize microtubules by mediating spindle positioning and movement in the budding process.  Potential target of the RHO family members (By similarity).
What are the official names of this protein?
BNI1-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the formin homology family. BNI1 subfamily.
Protein: PGK_DESAH
Sequence: MKTVREIEFNSKTVLVRVDYNLPMDENGNIADDNRIRATLPLVNYLVDKGAKIVLASHMGRPKGKPAASLSLAPAAKRLSELLGFEVVFVDDCIGPKVKERVDQLEPGQIILLENLRFYKGEEENDPEFARSLAELCQVYVNDAFAVSHRTAASIVAITRFVREACAGFLLEKEVKCFHDSIENPVHPLVAIIGGAKVSSKLGALENMLNHVDALVIGGAMANTFLKSQGNDVGASMVEEDLVETAAHIVQEARDRKINLILPVDLVVADRFDADAQTRVVDVKAVPQGWMALDIGPETGAIFARAIQRAATIVWNGPMGVFEMKPFCNGTKMVAAAVAAADAFSVVGGGDTGLAVNLCGVADKMSYVSTGGGAFLHLMEGKKLPGVTALD
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPID_ECOLI
Sequence: MTALLRVISLVVISVVVIIIPPCGAALGRGKA
What are the official names of this protein?
ilv operon leader peptide, ilvGMEDA operon attenuator peptide.
Protein: HEMA_I56A2
Sequence: MEKTLLFAAIFLCVKADEICIGYLSNNSTDKVDTIIENNVTVTSSVELVETEHTGSFCSINGKQPISLGDCSFAGWILGNPMCDELIGKTSWSYIVEKPNPTNGICYPGTLESEEELRLKFSGVLEFNKFEVFTSNGWGAVNSGVGVTAACKFGGSNSFFRNMVWLIHQSGTYPVIKRTFNNTKGRDVLIVWGIHHPATLTEHQDLYKKDSSYVAVGSETYNRRFTPEINTRPRVNGQAGRMTFYWKIVKPGESITFESNGAFLAPRYAFEIVSVGNGKLFRSELNIESCSTKCQTEIGGINTNKSFHNVHRNTIGDCPKYVNVKSLKLATGPRNVPAIASRGLFGAIAGFIEGGWPGLINGWYGFQHRNEEGTGIAADKESTQKAIDQITSKVNNIVDRMNTNFESVQHEFSEIEERINQLSKHVDDSVVDIWSYNAQLLVLLENEKTLDLHDSNVRNLHEKVRRMLKDNAKDEGNGCFTFYHKCDNKCIERVRNGTYDHKEFEEESKINRQEIEGVKLDSSGNVYKILSIYSCIASSLVLAALIMGFMFWACSNGSCRCTICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: CYSH_VIBC1
Sequence: MLDSVASKPELAELLTLTKTEQILRLAQINVELEQLSAQERVKWALENLEGEFAVSSSFGIQAAVMLHLVTQQKPDIPIILTDTGYLFAETYQFIDQLKAQLNLNLKVYRAKESANWQEARYGKLWEQGIEGIEKYNKINKVEPMRRALREQNVGTWFSGLRREQSQSRAGLPILSIQNGVFKFLPVIDWTNKDVHYYLEEHGLSYHPLWEQGYLSVGDTHTSRKWEPGMSEEETRFFGLKRECGLHEDDGSEQDGSGI
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBLP_DICDI
Sequence: MEQQKAPQVTYLEVGSLVGHNGFVTSIAVSPENPDTIISSSRDKTVMVWQLTPTDATSPGKAHRSLKGHSHFVQDVVISHDGQFALSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGSRDATIKVWNTLGECKFTLEGPEAHQDWVSCIRFSPNTPTIVSGSWDNKVKIWDIKSFKCNHTLTDHTGYVNTVTISPDGSLCASGGKDTFACLWELSSGKPLYKLEARNTINALAFSPNKYWLSAATDDKIIIWDLLTKQVLAEIVPEVKEQAFDSKKKKESKPKAPACLSLAWSADGSVLYAGYNDGLIRVYKSSSQ
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-like protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.