PharMolix/UniProtQA huggingface dataset:
Protein: HNT2_YEAS1
Sequence: MNKPIYFSKFLVTEQVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQYKADSINVAIQDGPEAGQSVPHLHTHIIPRYKINNVGDLIYDKLDHWDGNGTLTDWQGRRDEYLGVGGRQARKNNSTSATVDGDELSQGPNVLKPDSQRKVRALTEMKKEAEDLQARLEEFVSSDPGLTQWL
What is the function of this protein?
Cleaves A-5'-PPP-5'A to yield AMP and ADP.  Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine.  Is most effective on dinucleoside triphosphates.  Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock (By similarity).
What are the official names of this protein?
Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Hit family protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: CLSA_PROMH
Sequence: MTTFYTVLSWLTFFFYWLLIAGVTFRVLMHRRPVTSTMTWLLIIYILPLVGVIAYFAFGELHLGKRRVEHARQMWPSVVAWLEELKKCKHIFAKHYSDVAEPIFQLTAKRQGINGVKGNKIQLLTTCEDSLNAITRDINNARDNIEMVFYIWQSGGLVEEVTEALIQAAKRGVKCRIMVDSAGSRSFFRTNGPARMRAAGIEFVESLQVNLFRFFLRRMDLRQHRKIVLIDNYISYTGSMNMVDPRYFKQDAGVGQWIDIMVRMEGPVSTTLGIIYAFDWEMETGERHLPPPPDNNIMPFEQANGHTTQVIASGPGFPEELIQQSLITAIYSARKELVMTTPYFVPSDDLAHAISTAAMRGVDVSIIVPRSNDSFLVRWASRAFFTEILEAGVKVFQFEDGLLHTKSVMVDGQLSMVGSVNLDMRSLWLNFEITVVIDDECFASDLSIVQYDYIARSTQLTLDEWEKRPFMNRVLERLCYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BOL3_BOMPE
Sequence: IKIMDILAKLGKVLAHV
What is the function of this protein?
Mast cell degranulating peptide.
What are the official names of this protein?
Bombolitin-3, Bombolitin III.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Bombolitin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CBPYA_TALMQ
Sequence: MRGLATTLLIGAAAAATYPAQQVLKAPEEVLEKTHKTSSSSLAETLARPLHELNEELKSLTAEAEEVWEQVSNMFPGALDNIPFFSSPKKHTRRPDSHWDHIVRGADVQNIWVENENGEKEREVGGRLETFDLRVKAVDPSSLGIDPDVKQYSGYLDDNENDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFFELGPSSIGKNIKPIYNPYSWNSNASVIFLDQPVNVGFSYSGNSVSETSAAAKDVYALLTLFFKQFPEYATQDFHIAGESYAGHYIPSFASEILSHKKRNINLKSVLIGNGLTDGFTQYEYYRPMACGDGGYPAVLDESACRSMDNALGRCQSMIQSCYDSESAWTCVPASIYCNNALLGPYQRTGQNVYDIRKPCEGSSLCYADLEYISTYLNQAEVLKAVGAEVDSFDSCNFDINRNFLFKGDWMKPFHKLVPGILEEIPVLIYAGDADFICNWLGNKAWSDALEWSGHEEYAATELEDLEIVDNEHKGKKIGQVKSSGNLTFMRLFGGGHMVPYDQPEASLEFFNRWIGGEWTK
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: THIE_AZOVD
Sequence: MKLRGLYAITDSRLLADGRLLPYVEAALRGGARLLQYRDKSDEDARRLREAEALRDLCLRYGAQLIVNDDLELAARLGVGLHLGQQDGSLSAARALLGPKAIIGATCHGQLELAEQAAADGASYLAFGRFFDSSTKPGAPPASLELLERARARFPQPLVAIGGVTLDNAPELIRRGAAMIAVINALFAAANAAEVEQRARAFGQLFADT
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: MTDC_CHICK
Sequence: MATALCPLRALGQTAFRPRTRRLHLSAPRADAVVISGRKLARQIRQEARHEVEQWVAAGNKRPHLSVVLVGENPASHSYVLNKTKAAADVGISSETILKPASITEEELLDLISKLNNDANVDGLLVQLPLPEHIDERKICNAVTPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGRHERPGGDATVTISHRYTPKEQLKQHTIRADIVVAAAGIPNLITADMIKEGAAVIDVGITRVQDPITAKSRLVGDVDFEGVKKKASYITPVPGGVGPMTVAMLMKNTIIAAKKLLKPKALEALTA
What is the function of this protein?
Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency.
What are the official names of this protein?
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPA_RANMC
Sequence: MATLRADEISNIIRERIEQYNREVKIVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEKTVGIALNLESNNVGVVLMGDGLMIQEGSSVKATGRIAQIPVSEDYLGRVINALAKPIDGRGEISASESRLIESPAPGIISRRSVYEPMQTGLIAIDAMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQNVICVYVAIGQKASSVAQVVTTFQEQGVMEYTIVVAETADAPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSRLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNSGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQAAPLTVEEQVVTIYTGTNGYLDSLEIGQVKKFLVQLRTYLKSSKPQFQEIISSTKTFTEEAEVLLKEAIQEQMERFLLQEQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: REXO1_HUMAN
Sequence: MLRSTGFFRAIDCPYWSGAPGGPCRRPYCHFRHRGARGSGAPGDGGEAPPAAGLGYDPYNPELPKPPAQRENGTLGLGEEPRPDVLELELVNQAIEAVRSEVELEQRRYRELLETTREHRSAEAPALAPRGPNASPTVGPDEDAFPLAFDYSPGSHGLLSPDAGYQPTPLAAPAEPGSKYSLASLDRGQGRGGGGGGALEYVPKAVSQPRRHSRPVPSGKYVVDNSRPPTDLEYDPLSNYSARHLSRASSRDERAAKRPRGSRGSEPYTPAPKKLCDPFGSCDARFSDSEDEAATVPGNEPTTASTPKARADPEIKATGQPPSKEGLEAEGGGLRETKETAVQCDVGDLQPPPAKPASPAQVQSSQDGGCPKEGKPKKKKTGAPPAPSCKDGAQGKDKTKDKGRGRPVEKPRADKKGPQASSPRRKAERPEGTKKKPSSATPVATSGKGRPDRPARRPSPTSGDSRPAAGRGPPRPLQLPDRKSTKAPSGKLVERKARSLDEGASQDAPKLKKRALSHADLFGDESEDEAAGPGVPSVWPSALPSLSSDSDSDSDSSLGFPEAQGPPKRLKASPPPSPAPSSSSSSSSSTSSAGADVDYSALEKEVDFDSDPMEECLRIFNESTSVKTEDRGRLARQPPKEEKSEEKGLSGLTTLFPGQKRRISHLSKQGQEVEPPRRGPAVPPARPPTAQEVCYLRAQQAQRASASLLQAPARLAEKSPSVHISAPGEKRRIAHIPNPRLAAAPTGAKRTLAASGSQSSNGPEPGGQQLKTRTLSGMASKTTTTIIPKRIAHSPSLQSLKKPIIPKEFGGKVPTVIRQRYLNLFIEECLKFCTSNQEAIEKALNEEKVAYDRSPSKNIYLNVAVNTLKKLRGLAPSAVPGLSKTSGRRVVSHEVVLGGRLAAKTSFSLSRPSSPRVEDLKGAALYSRLREYLLTQDQLKENGYPFPHPERPGGAIIFTAEEKRPKDSSCRTCCRCGTEYLVSSSGRCIRDEECYYHWGRLRRNRVAGGWETQYMCCSAAAGSVGCQVAKQHVQDGRKERLEGFVKTFEKELSGDTHPGIYALDCEMSYTTYGLELTRVTVVDTDVHVVYDTFVKPDNEIVDYNTRFSGVTEADLADTSVTLRDVQAVLLSMFSADTILIGHSLESDLLALKVIHSTVVDTSVLFPHRLGLPYKRSLRNLMADYLRQIIQDNVDGHSSSEDAGACMHLVIWKVREDAKTKR
What is the function of this protein?
Seems to have no detectable effect on transcription elongation in vitro.
What are the official names of this protein?
RNA exonuclease 1 homolog, Elongin-A-binding protein 1, EloA-BP1, Transcription elongation factor B polypeptide 3-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the REXO1/REXO3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NTPPA_RUEST
Sequence: MAFILGSGSPRRLELLAQLGVTPDDIRPPDIDETPQKGELPRDYCARVTRQKAEAVTSNPEDLVLCADTTVVLGRRIMGKPRDAGEAAEFLLALSGRRHRVITSVALRKQDRLWQKDVVSQVKMKRLSDEELNAYLATGDWEGKAGGYAIQGPAGALIPWISGSFTAIVGLPLAETATLLQTAGYPLYKDTAS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_LACE2
Sequence: MREGIHPDYYQAKVVCNCGNEFVTGSTKEEIHVEICSKCHPFYTGQQKASSTRGRIDKFNKKYGVSNN
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RUVA_UREPA
Sequence: MNYLIFKVIYANANIVVGEHNFIGYQIRIPKDYELEINKFCKLYLYEYISIMPNKNLIIKDLYGFRTYNERLLFIDLISINSIGPKTAINILKYDIDTIIDAIATKNIDYLITIKGINQRNANLICDQLNYKYINKVNDKNNWAKELSIGLENLGYTKKDIEYAITKVKINSQQDIDISEIISSAIKEISLRHEN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RPE5C_ARATH
Sequence: MEETMAEEGCCENVESTFDDGTNCISKTEDTGGIESKRFYLARTTAFEMLRDRGYEVNEAELSLTLSEFRSVFGEKPELERLRICVPLRSDPKKKILVVFMGTEPITVKSVRALHIQISNNVGLHAMILVLQSKMNHFAQKALTTFPFTVETFPIEDLLVNITKHIQQPKIEILNKEEKEQLLRKHALEDKQLPYLQEKDSFVRYYGLKKKQVVKITYSKEPVGDFVTYRCII
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase V involved in RNA-directed DNA methylation-dependent (RdDM) silencing of endogenous repeated sequences, including transposable elements.
What are the official names of this protein?
DNA-directed RNA polymerase V subunit 5C.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y250_CORGL
Sequence: MQSNLLAVLFALASALTIAWGTVVRHRIALRTPKDGSLRSSPLLNALMTPMWWAGMSTAMLAYFLQTVALGFGTLLVVQPVLVLSLMFTLPLSARFNGYRLRRTEIFWATLLTVAVGIMIVLGRPLPGNPHPPLDRWIPVLLVGVAVMGGMWLLAEYVLKKDKALILGLVTGALFGYVAVMSKAAVDLFVHQGITGLILNWEGYGLILTALLGTIVQQYSFNAGELQKSLPAMTIAEPIVAFSLGYLVLGEKFQVVDWEWIAMGIALLVMIVSTIALSRTSTMPAGSKR
What are the official names of this protein?
Uncharacterized protein Cgl0250/cg0304, ORFX.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: P2C31_ARATH
Sequence: MVMEIVKPNTCIRGCCTSESIPLHLPSSSFTLLSPIAKGSESVVYEAILDGRRVAAKKPILSTSDDLDKFHRNLQLSCNLNHPGVAKLLAAHAKPPNYMFFFDFYESGTLAEKLHVEEWSPSIDQVLLITLHLAKALQYLHNNGIVHRDVKPANVLLDEKFFPYLADFGLAEYKKNLREVNLQNWRSSGKPTGGFHKKNMVGTLIYMAPEILRKDMYTEKADIYSFGILINELLTGVVPYTDRRAEAQAHTVLEMNYTEQQLTVAIVSSGLRPALAEIGLHLPKSLLSLIQNCWESDPSKRPSSDNVVLELESIWEQVRGKQQGHLLEKTSNSQSDTDGADIIKNSGDYRDTVNWFSQGECLSKKSSVSTVFDVKLWSSSTDEPSRYVPVISCGSFATCGRRESMEDTHFIIPHMCNEESIHLFAIFDGHRGAAAAEFSAQVLPGLVQSLCSTSAGEALSQAFVRTDLAFRQELDSHRQSKRVSQKDWHPGCTAIASLLVENKLFVANVGDSRAILCRAGHPFALSKAHLATCIDERNRVIGEGGRIEWLVDTWRVAPAGLQVTRSIGDDDLKPAVTAEPEISETILSADDEFLVMASDGLWDVMNDEEVIGIIRDTVKEPSMCSKRLATEAAARGSGDNITVIVVFLRPVSTAERIY
What are the official names of this protein?
Protein kinase and PP2C-like domain-containing protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PP2C family.
Protein: PHEA2_CHRSP
Sequence: KNGDLRTPVITIFDARGCKDHANKEYTGPKAGGADDEMCVKVAMQKIAVAEDAAALVLKECLSELKARKK
What is the function of this protein?
Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex.
What are the official names of this protein?
Phycocyanin-645 alpha-2 chain, PC-645.
What is the protein family that this protein belongs to?
Belongs to the phycoerythrin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: S35B4_DANRE
Sequence: MNTLFAVTLVFVGCCSNVVFLELLVRDFPGCGNIVTFAQFAFIALEGFIFETNFGRKKPQIPLSNYVIMVTMFFTVSVINNYALDFNIAMPLHMIFRSGSLIANMILGIIILKNRYSMSKYLSIVLVSVGIFICTIMSAKQVNVEKGGTEEDGVYAFMHWLLGIAMLTFALLMSARMGIFQETLYKKYGKHSKEALFYNHCLPLPGFLLLSTNIYNHAVLFSQSPPMEVPVIGLSMPVMWFYLLMNVITQYVCIRGVFILTTECASLTVTLVVTLRKFLSLIISILYFQNPFTAWHWVGTAVVFLGTLLYTEVLSSIPAAFKGYKVDKKAE
What is the function of this protein?
Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi.
What are the official names of this protein?
UDP-xylose and UDP-N-acetylglucosamine transporter, Solute carrier family 35 member B4.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: ATPG_SHESW
Sequence: MAGAKEIKTKIASVKNTQKITSAMEMVAASKMRRAQERMAASRPYAESMRKVIGHVAQGSLEYKHPYLEVREAKRVGYIVVATDRGLCGGLNVNLFKKVLLDLKNWKEQGAEVEFCPIGARSVQFFKSFGGTMPAHASGLGDAPSIADLIGTVRVMLKAYNEGKLDRLFIVFNKFVNTMTQAPVIEQLLPLPKSEEVANKHPWDYIYEPDPKVLLDTLLVRYIESQVYQGVVENIASEQAARMVAMKAATDNAGELINDLQLVYNKARQAAITQELSEIVSGASAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LMBL2_PONAB
Sequence: MEKPPSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDREAGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMVCVDGGPSTDGSDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPVRGDIIAVRVKEEHLDVPSPNKASSPELPVSVENIKQETDD
What is the function of this protein?
Putative Polycomb group (PcG) protein.  PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility.  Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.  Binds to monomethylated and dimethylated 'Lys-20' on histone H4.  Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' (By similarity).
What are the official names of this protein?
Lethal(3)malignant brain tumor-like protein 2, L(3)mbt-like protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: SC241_CANGA
Sequence: MSHHKRRVYPQAQFGLAQAGQTGYQDVQQPGVLPSQANYQEPVPLVTPIQEVLNNQIDQTADSLHNMQLHNVPDFNQPLQGQLNGPQSPALYQNYNENGMNNYNAAFGNGGTSVKQVNQLYPIDLLSDLPPPIKDLGLPPPPINLSPDIMSVPSDKSNASPDYIRSTLNAVPKTNSLLKKTKLPFALVIKPYQHLNDDVNAPPLNEECLIVRCRRCRSYINPFAKFIEQGRRWRCNFCRLANDLPMQFDQSSIDTNIVNRLDRTEIKNAVMEYVAPKEYTVRPPPPSIYTFIIDVSQNAIKNGLFVSTIETLKQQLEYLPNRDNRTKISIILVDHALHILSIPADDVSNKFRILDVADIDEPYIPLPNSLVVSLSRCKQNVQLALEKIKQLFEINVSTKFALGPALRTAQKLIGGVGGKLIVISASLPNAGIGSLQRRNESGVSGTTKESSQLLSCQDSFYKTFTVECSKTQITIDLFLASDDYVDVATLSNLPRYTAGQTHFYPGYNASNISDFNKFTTEFSKHITMDISFETVMRARGSTGLKTSAFYGHFFNRSSDLCAFSTMPRDQSYVFDISIEDTITTDYCYFQVAVLLSLNNGQRRIRVITLALPTTQSISEVFACVDQQAVAAQITQRAVQKANSSSIDDARDLIQKTTLDILSTYKKELVVTNTGGVVPLKLSTNLRILPLLMHALMKHMAFRAGVVPSDHRAYSLNVLESVPIKSLITSIYPSIYSMHDMGDDCGYTDETGNVILPECINDTAILMEKYGLYLIDNGSELFLWVGGEAVPELLSDVFGVPEMSQVPVGKHDLFRVEGSQFNERVCNIIDQLRTSDDTTVYKTLYIVSGPTINDSFSQGTRELASLRMWAATAFVEDNIMKTLSYREFLEKMKKEVSK
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC24-1.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CH60_THEM4
Sequence: MAKMLRFSEEARRALERGVDAVADAVKITLGPKGRNVVIEKSWGSPTITNDGVSIAKEIELEDKFENLGAQLVKEVASKTNDVAGDGTTTATVLAQAMIKEGIKNVTAGANPILVKRGIDKAVAAAVEKIKDISKKLSNSDDIAHVASISANSEEIGKLIAEAMEKVGEDGVITVEDSKSIDTFVEFTEGMQFDRGYISPYFVTDPEKMEVVYNEPFILITDRKLSNIKPLIPILEKVAQTGKPLVIIAEDVEGEALTTLVLNKLKGTLNTVAVKAPGFGDRRKAMLQDIAILTGGIVASEEVGINLEDLTLNDLGRADVVRVKKDETIIVGGHGDQEEIKKRIAQIKAQIEQTTSEYEKETLQERMAKLAGGVAVIKVGAATETELKEKKHRIEDALSATRAAVEEGIVPGGGITLLRARKPVEKIVEELDGDEKIGAKIVYEALSAPINQIAKNAGYDGAIIIHKVLEQDDPAYGFDALKGEYCDMFERGIIDPAKVTRSALQNAASIAGMLLTTEVLVVEKPEPKNNNPMPEMPEY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAHL2_ORYSJ
Sequence: MKFAKKYEKYMKGMDEELPGVGLKRLKKLLKKCRSDLQSHENDGSSAGRCPGHCSVCDGSFFPSLLNEMSAVIGCFNEKAKKLLELHLASGFKKYTMWFTSKGHKSHGALIQQGKDLVTYAIINAVAMRKILKKYDKIHYSKQGQEFKAQAQSLHIEILQSPWLCELMAFYMNLRRSKKNNGAMELFGDCSLVFDDDKPTISCNLFDSMRVDISLTCSICLDTVFDPVALSCGHIYCYLCSCSAASVTIVDGLKSAERKSKCPLCRQAGVFPNAVHLDELNMLLSYSCPEYWEKRIQMERVERVRLAKEHWESQCRAFLGM
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase BAH1-like 2, RING-type E3 ubiquitin transferase BAH1-like 2.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family.
Protein: ALG6_ARATH
Sequence: MPKKKPAKHSGEDDITIPVSPQTGSSIDTWWWLTHKGTTTSFLCISLFALLIRSAVTMYPYSGAGIPPKFGDFEAQRHWMEITTNLPVIDWYRNGTYNDLTYWGLDYPPLTAYQSYIHGIFLRFFNPESVALLSSRGHESYLGKLLMRWTVLSSDAFIFFPAALFFVLVYHRNRTRGGKSEVAWHIAMILLNPCLILIDHGHFQYNCISLGLTVGAIAAVLCESEVLTCVLFSLALSHKQMSAYFAPAFFSHLLGKCLRRKSPILSVIKLGIAVIVTFVIFWWPYVHSLDDFLMVLSRLAPFERGIYEDYVANFWCTTSILIKWKNLFTTQSLKSISLAATILASLPSMVQQILSPSNEGFLYGLLNSSMAFYLFSFQVHEKSILMPFLSATLLALKLPDHFSHLTYYALFSMFPLLCRDKLLIPYLTLSFLFTVIYHSPGNHHAIQKTDVSFFSFKNFPGYVFLLRTHFFISVVLHVLYLTIKPPQKYPFLFEALIMILCFSYFIMFAFYTNYTQWTLSSHFGSSDKEKKQI
What is the function of this protein?
Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity).
What are the official names of this protein?
Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 6 homolog, Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG6/ALG8 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HSCA_RICTY
Sequence: MQIIEITEPKQTDCQQKLQIAVGIDFGTTNSLIAIATNRKVNIIKSKGDKELIPTTIDFINEDLIIGNNKGLRSIKRLFGKTLKEILNTKTLFALVKDYLDINSSELKLNFANKKMRIAEIAAEVFIYLKNQAEKQLKNNITKAVITIPAHFNDTARGEIMLAAKIAGFEVLRLIAEPTAAAYAYGLNRNQTGRYLVYDLGGGTFDVSILNIQEGIFQVIATNGDNMLGGDDIDVVITQYICNKFDLPNSSETLQLAKKAKETLTYKESFNNDIISINKQTLEQLIFPLVKHTINITQECLEQSGNPNIDGVILVGGTTRIPLIKDELYKAFKINILSDIDPDKAVVCGAALQAENLIAPHTNSLLIDVVPLSLGIELYGGIVEKIIMRNTPIPIAVIKEFTTYADNQTGIQFHILQGEREMAADCRSLARFELKGLPPMKAGNIRAEVTFAIDADGILSISAYEKISNISHTIEVKPNHGIDKTEIEIMLENAYKNASIDYTTRLLQEEIIETEALISNIERSIIELTTLLSESEISIINALFDNIKYAVQTRDQTLIKHSIKEFKSKIKNIWIQNIININDLRK
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MFN2_HUMAN
Sequence: MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDTYRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIKQITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSDRCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQEDIEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKKIEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
What is the function of this protein?
Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:11181170, PubMed:11950885, PubMed:26214738, PubMed:28114303).  Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:28114303).  Overexpression induces the formation of mitochondrial networks (PubMed:28114303).  Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable).  Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (By similarity).  Plays an important role in the regulation of vascular smooth muscle cell proliferation (By similarity).  Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) (PubMed:23620051).  Is required for PRKN recruitment to dysfunctional mitochondria (PubMed:23620051).  Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress (By similarity).  Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions (By similarity).
What are the official names of this protein?
Mitofusin-2, Transmembrane GTPase MFN2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=Colocalizes with BAX during apoptosis.