PharMolix/UniProtQA huggingface dataset:
Protein: NRAM3_ARATH
Sequence: MPQLENNEPLLINEEEEEETAYDETEKVHIVRNEEEDDLEHGVGCGGAPPFSWKKLWLFTGPGFLMSIAFLDPGNLEGDLQAGAVAGYSLLWLLMWATAMGLLVQLLSARLGVATGRHLAELCRDEYPTWARMVLWVMAELALIGSDIQEVIGSAIAIKILSNGILPLWAGVVITALDCFVFLFLENYGIRKLEAVFAVLIATMGVSFAWMFGQAKPSGSELLIGILVPKLSSRTIQKAVGVVGCIIMPHNVFLHSALVQSREVDKRQKYRVQEALNYYTIESTIALFISFLINLFVTTVFAKGFYNTDLANSIGLVNAGQYLQEKYGGGVFPILYIWAIGLLAAGQSSTITGTYAGQFIMGGFLNFKMKKWLRALITRSCAIIPTIIVALVFDSSEATLDVLNEWLNVLQSIQIPFALIPLLCLVSKEQIMGSFKIGPLYKTIAWLVAALVIMINGYLLLEFFSNEVSGIVYTGFVTLFTASYGAFILYLIARGITFTPWPFKAESSH
What is the function of this protein?
Vacuolar metal transporter involved in intracellular metal homeostasis.  Can transport iron (Fe), manganese (Mn) and cadmium (Cd).  Regulates metal accumulation under Fe starvation.  Acts redundantly with NRAMP4 to mobilize vacuolar Fe and provide sufficient Fe during seed germination.  In association with NRAMP4, required for optimal growth and photosynthesis under Mn deficiency.  Exports Mn from vacuoles in leaf mesophyll cells, making Mn available for functional photosystem II in chloroplasts.  Involved in basal resistance to the bacterial pathogen E. chrysanthemi.
What are the official names of this protein?
Metal transporter Nramp3, AtNramp3.
What is the protein family that this protein belongs to?
Belongs to the NRAMP (TC 2.A.55) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: NUOK_MYCA9
Sequence: MNPDNYLYLAALIFTIGAAGVMLRRNAIVVFMSVELMLNAANLAFVTFARMHGNLDGQVIAFFTMVVAATEVVVGLGIIMTIFRTRRSASVDDADVLKF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y303_ENCCU
Sequence: MCFPVGGLLPYLALRSVAYICVFGDSSRAPDLIREAFESPHFKRFDGAGTYKEAKGRCGMRFADVVNGAFGQISDMADKVGKGEPEVWCIWKKRGEVEMLLKVKEYRKGYGSGKRRRR
What are the official names of this protein?
UPF0329 protein ECU03_0030/ECU05_0040/ECU06_0010/ECU06_1710/ECU11_0010.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: CYC_ORYSJ
Sequence: MASFSEAPPGNPKAGEKIFKTKCAQCHTVDKGAGHKQGPNLNGLFGRQSGTTPGYSYSTANKNMAVIWEENTLYDYLLNPKKYIPGTKMVFPGLKKPQERADLISYLKEATS
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: YAA4_YEAST
Sequence: MGVTSGGLNFKDTVFNGQQRDIESTTTQVENQDVFFLTLLVQTVSNGSGGRFVNNTQDIQTSNGTSILGSLSLRIVEVSWDSDDSVIDLGSQVRFGSFLHLTQDHGGDLFWGKVLGFTLKFNLNLRLTVNIDQLEWEVLHVSLHFWVVEVSTDQTLSVENGIRRIHSSLILSSITNQSFSVSESDKRWSGSVTLIVGNNVHTIISKVSNTRVCCT
What are the official names of this protein?
Putative uncharacterized protein YAL004W.
Protein: TARA_STAAS
Sequence: MTVEERSNTAKVDILGVDFDNTTMLQMVENIKTFFANQSTNNLFIVTANPEIVNYATTHQAYLELINQASYIVADGTGVVKASHRLKQPLAHRIPGIELMDECLKIAHVNHQKVFLLGATNEVVEAAQYALQQRYPNISFAHHHGYIDLEDETVVKRIKLFKPDYIFVGMGFPKQEEWIMTHENQFESTVMMGVGGSLEVFAGAKKRAPYIFRKLNIEWIYRALIDWKRIGRLKSIPIFMYKIAKAKRKIKKAK
What is the function of this protein?
Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.
What are the official names of this protein?
N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase, N-acetylmannosaminyltransferase, UDP-N-acetylmannosamine transferase, UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
Protein: GATY_SALSV
Sequence: MFIISGRTMLKKAQQEGYAVPAFNIHNLETLQVVVETAAELRSPLIVAGTPGTFSYAGVGNIVAIAAELAKSWNHPLAVHLDHHEKLADIKMKVAAGVRSVMIDGSHFPFADNIALVKSVVDYCHRYDVSVEAELGRLGGQEDDLIVDGKDALYTHPEQAREFVEKTGIDSLAIAIGTAHGLYTAEPKLDFERLTEIRQRVDVPLVLHGASGLPTRDITRAISLGICKVNVATELKIAFSDALKNYLTQHAEASDPRHYMIPAKAAMKEVVRKVIADCGCEGKL
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: VATB_HALVD
Sequence: MKEYQTITEISGPLVFAEVDEPIGYDEIVEIETPQGETKRGQVLESSEGLVAIQVFEGTSGIDRNASVRFLGETLKMPVTEDLLGRVLDGSGQPIDGGPEIVPDERRDIVGAAINPYSREYPEEFIQTGVSAIDGMNTLVRGQKLPIFSASGLPHNDLALQIARQATVPEDEESGEESEFAVVFGAMGITQEEANEFMEDFERTGALERSVVFTNLADDPAVERTVTPRLALTTAEYLAFDKDYHVLVILTDMTNYCEALREIGAAREEVPGRRGYPGYMYTDLAQLYERAGRIQGRDGSVTQIPILTMPGDDDTHPIPDLTGYITEGQIYIDRDLNSQGIRPPINPLPSLSRLMDDGIGEGLTREDHADVSDQMYAAYAEGEDLRDLVNIVGREALSERDNKYLDFAERFEAEFVNQGFDTDRSIEDTLDIGWDLLSTLPKSELNRIDEELIEDYYEDDAESVEAEA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: CSLD4_ORYSJ
Sequence: MSRRLSLPAGAPVTVAVSPVRSPGGDAVVRRGSGLTSPVPRHSLGSSTATLQVSPVRRSGGSRYLGASRDGGADESAEFVHYTVHIPPTPDRATASVASEAEAAAEAEEVHRPQRSYISGTIFTGGLNCATRGHVLNFSGEGGATAASRAAASGNMSCKMRGCDMPAFLNGGRPPCDCGFMICKECYAECAAGNCPGCKEAFSAGSDTDESDSVTDDDDDEAVSSSEERDQLPLTSMARKFSVVHSMKVPGAAANGNGKPAEFDHARWLFETKGTYGYGNALWPKDGHAHSGAGFVAADEPPNFGARCRRPLTRKTSVSQAILSPYRLLIAIRLVALGFFLAWRIRHPNPEAVWLWAMSVACEVWFAFSWLLDSLPKLCPVHRAADLAVLAERFESPTARNPKGRSDLPGIDVFVTSADPEKEPPLVTANTILSILAADYPVEKLACYLSDDGGALLSFEALAETASFARTWVPFCRKHGVEPRCPEAYFGQKRDFLKNKVRVDFVRERRKVKREYDEFKVRVNSLPEAIRRRSDAYNAGEELRARRRQQEEAAAAAAAGNGELGAAAVETAAVKATWMSDGSHWPGTWTCPAADHARGDHAGIIQAMLAPPTSEPVMGGEAAECGGLIDTTGVDVRLPMLVYVSREKRPGYDHNKKAGAMNALVRTSAIMSNGPFILNLDCDHYVHNSSALREGMCFMLDRGGDRVCFVQFPQRFEGVDPSDRYANHNLVFFDVSMRAMDGLQGPMYVGTGCVFRRTALYGFSPPRATEHHGWLGRRKIKLFLTKKKSMGKKTDRAEDDTEMMLPPIEDDDGGADIEASAMLPKRFGGSATFVASIPVAEYQGRLLQDTPGCHHGRPAGALAVPREPLDAATVAEAIGVISCFYEEKTEWGRRIGWIYGSVTEDVVTGYRMHNRGWRSVYCVTPRRDAFRGTAPINLTDRLHQVLRWATGSVEIFFSRNNALFASPRMKLLQRVAYFNAGMYPFTSVFLLAYCLLPAVSLFSGKFIVQRLSATFLAFLLVITLTLCLLALLEIKWSGITLHEWWRNEQFWVIGGTSAHPAAVLQGLLKVIAGVDISFTLTSKPGNGGGDGGVGGEGNDDEAFAELYEVRWSYLMVPPVTIMMVNAVAIAVAAARTLYSEFPQWSKLLGGAFFSFWVLCHLYPFAKGLLGRRGRVPTIVFVWSGLISMIISLLWVYINPPAGARERIGGGGFSFP
What is the function of this protein?
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
What are the official names of this protein?
Cellulose synthase-like protein D4, OsCslD4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: NOG1_SCHPO
Sequence: MATAVFKNITPIPDVNTFLDVVLSRTQRKTPTVIRSGFKISRIRGFYGRKVKFTQDTITEKLDSILQEFPKLNDIHPFHADLLNILYDRDHLKIALSQLSTAKHLVENVARDYIRLLKYGDSLYRCKQLKRAALGRMATIIKRQKSSLEFLEQVRQHLSRLPAIDPNTRTLLVCGYPNVGKSSFMNKVTRAQVDVQPYAFTTKSLFVGHFDYKYLRWQVIDTPGILDHPLEQMNTIEMQSITAMAHLRSAVLYFMDLSEMCGYSVAAQVKLYHSIKPLFANKVTILVLNKIDAMRPEDLDQKNQELLQTIIDDGNVKVVQTSCVQDIGVMDVRTTACEALLAARVEQKLKGSRVNNVLNRIHLAEPAARDEVARPACIPDSVKTRRAYDANDPNRRILARDIEAANGGAGVYNVELRDKYILQDPSWKYDRMPELLDGKNVADFVDPEIEAKLLALDEEEERLEREGYYDSDQEIEDADEEEVLEKASRIREKNKLTMLAARQKKIKNRPVLPRTAGIRTLDELQSSLQSAGLPSDSIEERARSRARTAAANEMADGSGVDLLMNEGEEIRSKSIAPRSQSNRRESGVHAEGARSYADRLARVKQIHRNRMARASESDRHVIAAKPKHLLSGKRGNGKTQRR
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Probable nucleolar GTP-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CEIP2_HUMAN
Sequence: MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATFAFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQASKAH
What is the function of this protein?
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (PubMed:28246172).  Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity).  Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate (PubMed:28246172).
What are the official names of this protein?
Cell surface hyaluronidase, Cell migration-inducing hyaluronidase 2, Transmembrane protein 2.
What is the protein family that this protein belongs to?
Belongs to the CEMIP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: EIS1_YEAST
Sequence: MSLISAVEDRDIHNIGKTSGGGSRTSSITSSKKSLKHGSKSLRKPKVYQTTGEPLSREALYKAKLKYGVYQSPAQSYSIGVSDAHAASDKAANLAHDNQTTVEAYKRMFIDPNATKAASKMGPKVVRNNSITSATSKTSKESQTKRKSKESPGAAASKAYSMTMETTSLSSQTNSRSYSITSASSVLSGASGSFNSTVNPKPKTLNLEKVLVGAEKKAESRIKERWEPEKTNFQYGVKTDEHGNLNQFSFSNEMMNNIMAKVDAPKAQDLQKVKKVSAEKEAKSMKFALGAANAVKDMHPGEDIDKSIALKAQKRETYLSQLTSQQVLTLARANVDRQLDIIEKSDMHRKLFTNMEYNKAAVAVAQSNHQKKTEFHNKINMGGGLFLSPEDITKIASGLISPVLGEVSERAEAQRAMDEEIAERTEAYNKSSNEWETMERSIISNDAKVLTTTANRHQTEKKTSQEKIKASFDALVARMDTKVAERETLLEDTKSKEIEFKKQMQQELKDEKARLDQDLEEWGKKCEQDITEARKEQEELLKPYHDDLANAEAEHKTLVEERDEINAEISRLQDAIVDHKRKISGYGNDLDAQKNRNIREDDKLLELGQTKESLESHLNDDVIILANKAKEQAELSTKEARLKQLEVDSLINERKSELNATEIELKKEKLNLLEAMKDVASARGDDKIDEEKVKKLIGMTSEEYLTQNKSVEKNVEDLPTQLEKIEEGDELKKEEIVGAETKNSGGDGVPVSTAAKEATETSSAVQTKEPEEKISIGNKSSGKEDANDCKSAEHSKEISVSQKAGNNKSLGVSPDSLEHTFSGFSQGSSIEDDQDAISNQEKK
What is the function of this protein?
Required for normal formation of eisosomes, large cytoplasmic protein assemblies that localize to specialized domains on plasma membrane and mark the site of endocytosis.
What are the official names of this protein?
Eisosome protein 1.
What is the protein family that this protein belongs to?
Belongs to the EIS1 family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes at the eisosomes.
Protein: PYRB_GEODF
Sequence: MAFKHKDIIGLQDLTREEIELLLSTAENLKEINSREIKKVPTLRGKTVVNLFYEASTRTRTSFEIAAKRLSADTINITASTSSVTKGETLSDTARNVLAMNPDIIVMRHAVSGAHHYLAKRVSCSVINAGDGAHEHPSQGLLDMLTMRQQFGKLEGLKVAIVGDITHSRVARSDIYGLTRMGANVFLAGPPTMMPPGIERLGNVTVCKDMREAVADADVVMMLRIQLERQGKTLLPTMKEYSRYFGLNQSVLKLAKKDAMVMHPGPINRGVELSSDVADGSQSHILKQVENGVAVRMSMLYHVSGGELPTE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: F16PA_ALKEH
Sequence: MDQSRMTLGRFLAQQCPQDEKGKALALLLRQVGDSCRRIADAVAGGALREMTGAADNVNVQGEEQKKLDVFANDVLIEGCNWGGTVAGMASEEEDDIYTLPEGEPRGPWLLLFDPLDGSSNIDVNVSVGTIFSVLPAPDTGRDPVNEDLLQPGHRQVAAGYAVYGPSTVLVLTLGDGVYAFTLDRGQGEWFLTSSKMKVPEQTAEFAINCSYQRIWPAPIKRYIEECLDGEEGPRGKRFNMRWIASMVADLHRIFTRGGVFLYPADEKRPNGRLRVLYEINPMSMLMEQAGGEAFTGKERALDLQPEALHQRSGLMLGSREEVEVLRRYYAEQ
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_PYRAE
Sequence: MSQEIRAIVRIGDTDLDGNKQVAYALAKIRGIGIASAYAICWKLGIDPHAILGALPEDQINKLDWAVRNLHELAPAWFLNRRKDPETGRDLHLIGSELVLAAKRDVDLMKKLKSWKGVRHSLGLKVRGQRTVTTGRFGATAGVTKKKAAAGK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL4_METAC
Sequence: MATAKTIDLTGKAVGEVELPAVFDADYRPDLIKKAVLAAQANRLQPYGPRLYSGMETSARGWGSGRGVSHVPRLVNSSRAARVPHAKGGRRAHPPKPEADRSEKVNTKERRYAIRSAIAATTDPTLVSLRGHIFEAELPIVAVNDLESLERTKQVIEFLEAAGLYEDVLRAKYGRHIRAGRGKLRGRKYKHKKSVLIVAGENTPILKAARNLSGVDVVTVDSLNAELLAPGTHAGRLTVWTESAIGKLEGAFQ
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ISPG_ALIFM
Sequence: MHIESPIKRRQSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVDATVAQIKSLEKVGADIVRVSVPTMDAAEAFKVIKQQVSVPLVADIHFDYRIALQVAEYGVDCLRINPGNIGNEQRIRSVVDCARDKNIPIRIGVNGGSLEKDIQAKYKEPTAEALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVDSYRLLAKQIAQPLHLGITEAGGARAGSVKSAVGLGMLLSEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIATVNELEQRLEDLITPMDVSLIGCVVNGPGEAEVSHMGIAGSNRKSAFYEDGVRQKERFDNDNIVDQLEAKIRAKAAMLSKENQIDINQID
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: VIF_SIVSP
Sequence: MEEEKNWIVVPTWRIPGRLEKWHSLIKHLKYNTKDLQKACYVPHHKVGWAWWTCSRVIFPLKDEAHLEVQGYWNLTPEKGWLSTYAVRITWYSRNFWTDVTPDYADTLLHGTYFPCFSEGEVRRAIRGEKLLSCCKFPKAHKNQVPSLQYLALTVVSHVRSQGENPTWKQWRRNNRRGLRLARQNSRRNKQGSSESFAEGTNFPGLAKVLGILA
What is the function of this protein?
Counteracts the innate antiviral activity of APOBEC3G.  Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions.  Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery.  Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1.  Binds viral RNA and affects the stability of viral nucleoprotein core.  May play a role in viral morphology (By similarity).
What are the official names of this protein?
Virion infectivity factor, Vif, Q protein, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=Seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor (By similarity).
Protein: GLK_KLEP3
Sequence: MTKFALVGDVGGTNARLALCDLASGEISRAKTYSGLDYPSLEAVVRVYLEEHQVTVNEGCIAIACPITGDWVAMTNHTWAFSIAEMKRNLGFAHLEIINDFTAVSMAIPMLKAEHLIQFGGSAPVAGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEGIILEELRAELGHVSAERVLSGPGLVNLYRAIVKSDGRLPENLQPREVTERALADSCTDCRRALSLFCVIMGRFGGNLALTLGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFKAYVQDIPVYLIVHENPGLLGSGAHLRQTLGQVL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_CUPMC
Sequence: MAFVKRDNKNKKRFQQQNPLFKRKRFCRFTVAGVEQIDYKDLDTLKDFIGDNGKITPARLTGTKAHYQRQLDTAIKRARFLALMPYTDLHKN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: AMT12_ALTAL
Sequence: MSLLITSLAWGALLDPEVSSASKVALLDAVLEASTLLLRQNGSVRKFLALVAVLCLAEKTGSDNLPALILGSISTAASLSLHLETALRKSCVSNDQAVQTKRAMWILYCIDKSYALRWQTFSLVGDGSLPTTNPPDTALPSEVATTLSLEWLRIRSQYSKICSNILQLGVGAEGEPSENRSNRAVVLSAALEEWYGSVEISQMMLSLEHSDAVHMKLQTSYHYYEARFQLLSISLPDPRSSSPTGSQECREVLRRSIREVITGSNTITSEYLLQDCNHLFIQTLALSMLALDILLESDQGCGKENRALLSIVAGFFARVDIILPQSSIFEEVSNLIEILTYR
What is the function of this protein?
Part of the gene clusters that mediate the biosynthesis of AM-toxins, host-selective toxins (HSTs) causing Alternaria blotch on apple, a worldwide distributed disease (Probable).  AM-toxins are cyclic depsipeptides containing the 3 residues 2-hydroxy-isovaleric acid (2-HIV), dehydroalanine, L-alanine which are common for all 3 AM-toxins I to III.  The fourth precursor is L-alpha-amino-methoxyphenyl-valeric acid (L-Amv) for AM-toxin I, L-alpha-amino-phenyl-valeric acid (L-Apv) for AM-toxin II, and L-alpha-amino-hydroxyphenyl-valeric acid (L-Ahv) for AM-toxin III (Probable).  AM-toxins have two target sites for affecting susceptible apple cells; they cause invagination of the plasma membrane and electrolyte loss and chloroplast disorganization (PubMed:22846083).  The non-ribosomal peptide synthetase AMT1 contains 4 catalytic modules and is responsible for activation of each residue in AM-toxin (PubMed:10875335).  The aldo-keto reductase AMT2 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV), one of the precursor residues incorporated by AMT1 during AM-toxin biosynthesis, by reduction of its ketone to an alcohol (PubMed:15066029).  The cytochrome P450 monooxygenase AMT3 and the thioesterase AMT4 are also important for AM-toxin production, but their exact function within the AM-toxin biosynthesis are not known yet (PubMed:17990954).  Up to 21 proteins (including AMT1 to AMT4) are predicted to be involved in AM-toxin biosynthesis since their expression ishighly up-regulated in AM-toxin-producing cultures (PubMed:17990954).
What are the official names of this protein?
AM-toxin biosynthesis protein 12.
Protein: DRC7_DROME
Sequence: MPKVLFQKYKKVVSNIDPSRYSAKFKEIDEQRRSQGSESDFADEMEGEFEAEMEEMGSSEFSLSEGEPSLNIGKIDLSFPETVEEFENSPQCYPPSYYTLSPKERLLLLYAENFRKQLVLSYPKRRAMVLALPNECKVQKFVCTTIRPTAFIYTQLISSVEEIAKFVADFIQYEPLQDPINLPNRLISPETLLRKRKGNSYEMATLLVSMLIGAGHPALVVSGVAREETILNDQLAVPYPYPIVEVEVEEVKPKVEKPGQKYKLRGLPDLKSHLEEDMAEVHRQKEAEEKRIQDEIIRKQMEDLELLAVDRYHYRRSHAWVVIINNAPWSVKPKTTYTDVNGDVVEAPPTAIFIEPSTGFICETGCKQYILVDSIWNEYNYYVCKQKHQRVSELRWDLRDTKDWEHMLPGEPPEMRIYKMASDENVADEERDISEEKHLDCIGSWVERLHIGLADFEQRFPSSEKKIQYKGAIHERFSPYSQRDGKVMQLTIFNNDECTIPKVRYEYYENRSDLMRHVKYTYATDQFEEIFNKGRNDSLKSIEYFSDPSQQRKVHFFSASRIDSLELMVVEPGSLILHYKDRSDKCWYKEFEFTPAGNVLKKVTEKFLKASANDVCSNDIATRTFLFQQNKIVLKFHYTFGALTATVVEFTKPPRPDYGKELIYDEKLTKIYKANPLDPTRTNLELYRLLCEQLQYEDHLRKNFEKIFEDINNVFDLRKSEKAEPKLKFSIFDPLRNGAARAIRMRQFEEEEELKKEIASKPADFLAPYLVPYKHQEELTPEQSQNAYNACLNDLKSRFVSLLNNLQRHYEDLTSESKSLNRFLNKFENQFNNYDYKRLVQQSKDLELNKRMVQQRLTLTHEESQKKYEVVKNSLLKDPRLNFKKDDLARRASETSK
What is the function of this protein?
Key component of the nexin-dynein regulatory complex (N-DRC), essential for N-DRC integrity.  Involved in the regulation of flagellar motility (By similarity).  Involved in sperm motility.  Required for the sperm to enter in the coiled storage seminal receptacle (SR) tubule (PubMed:21289096).
What are the official names of this protein?
Coiled-coil domain-containing protein lobo, Lost boys protein.
What is the protein family that this protein belongs to?
Belongs to the DRC7 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme. Note=Detected as regular puncta along the flagellum.