PharMolix/UniProtQA huggingface dataset:
Protein: PKIB_EMENI
Sequence: MAISSTADLAPSRKARGSESNDRALKLFIELLSVETQQQLFRGEPCIQRFVEIGPRTILSTMAKRSASIQKDQRSSASCYSPEFLSYHDNQPEILYQYQNDQAIYPLSQPTQPQFEPTSPSHLTKRSPSPSKALPMSAIPSAELTLQAGHVILAMTAQKLRRRFDQVPVEKTIRDLSGGKSTLQNELTGDLVAEFGRVPEGVEDQPLSSLAESFQPEFSGIPGKAMSTLISRFISGKMPAGFNQSAIQEYLNSRWGLTKSHATIPLCFAPTMEPARRLANADEARAYLDDLVEKHAAFQGISLVPSNQVADGHESLAPVVMNVADVDEMNKRTKLYRAQFDSLASYLGVDYFASEKAMSESESRIAELEETIRLLNTELDEQFIKGIKPSFNIKQVRKYDSWWNWSREELIRLLNEICQDSSSACPPDMENRLQNLLNKWDANCSEIVRAHLIGLQSRSSAPMNKLQLILEEIFTLGNQTLSIDPLFVHNLPPMGPQTIITDAGCLEYHELPRQISHYPEAMAYGPPWPQGHTSAPFIHIKTREDGQDWMYDSKATSIYHAMLDVGVTTGLTFTHKAVLVTGAGPSSIAASVIQGLLSGGARIIVTTSRSISQSADFYQQMYRQYGAKGSSLSLFPFNQASKQDCEQLVQHIYGPDSPTDGDLDYILPFAAIPQVGEPDAFGGRQELALRAMLVNILRLIGFVRQEKERLRIENRPTMIVLPMSCNEGTFGGDGLYSEAKIGLKALFNRFYSENWSKYLTICGAVIGWTRGTAIMQTSNAVAEEVEKLGVITFTQAEMAFNILALMTPALTALAEDTPIYADLTGGLGSMWNIKQEISAARKRISERQILQIAIAEEDAREQAMICSASTDVESGLPTTRHARLGLQFPPLPDVNEGYPNIEGMIDLTRIPVIVGYSELGPWGNARTRWEIEHRGDFSLEGYIEMAWIMGLIKHVDGHAKGRPYVGWVDADTETPIQDYEVPHKYHKHIMAHAGLRLIKPTKLDSYDPSRKELLHEVAVEEDLAPFETSKSTAEAFKLRHGDCVTLLPIADSDNCRVYIKKGAVLMIPKAVPFDQVVAGRIPEGWDPARYGIPEEIVQQVDVTTLYALCCVSEAFLSAGIKDPYEIYQYIHVSELANCLGSGGGPMKVIQNMYRDRFLDRQIRGDIILEHFVNTMGAWVNMLLLSATGPLKTPVGACATAIESLDIGCEAIQNGRCKVAVVGGCDDYGEELAFEFANIKATANSTEELSKGRTPADISRPTASSRSGFAESAGCGVQILMSAALAIEMGLPIYGVVAYTHMASDQIGRSIPAPGKGILTAARENGQAKESPLLDLNFRRAVFDAEVALINKSHPKQATTLKPDHSETSNAASLRIRDAQNRWANNIRLSDPSISPIRASLATWGLTVDDIKVVSMHGTSTKANEVNEGNVINTQMRHLGRQMGNPLLAVCQKSLTGHPKAGAGAWQLNGCLQMMQENIVPGNRNADNIDKQLREFEHIVYPMESLRVPEIKATLLTSFGFGQKGAINIMVSPRYLFASLSNSDYEDYRSRTTKRQRSATPTFVSRIMKNNLVQVKTRPPWNDPEAMQNFFLDPNSRVVDGQITRAPRTAYKHQDISVPQSAAVSVNEALHAMLATTDHSSPAASASVGVDVEEISSINVDNPIFISRNFTLLERDYCLSAPDPRASFAGRWVAKEAAFKSLQTTSTGAGTAMDQIEILEVGGIPKVVRLTSQLHGHAHEVAFAQGITNIQITISHCNNTAIAVALALRKND
What is the function of this protein?
Fatty acid synthase alpha subunit; part of the pki gene cluster that mediates the biosynthesis of 2,4-dihydroxy-3-methyl-6-(2-oxoundecyl)benzaldehyde (PubMed:22510154).  The first step in the pathway is the generation of the decanoyl starter unit by the FAS composed of subunits pkiB and pkiC, which is then transferred directly from the FAS to the SAT domain of the non-reducing polyketide synthase pkiA (PubMed:22510154).  PkiA condenses the decanoyyl starter unit with 4 malonyl-CoA units and performs one methylation step to yield 2,4-dihydroxy-3-methyl-6-(2-oxoundecyl)benzaldehyde (PubMed:22510154).
What are the official names of this protein?
Fatty acid synthase alpha subunit pkiB.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.
Protein: SYE_RHIE6
Sequence: MTTSGVRVRIAPSPTGEPHVGTAYIALFNYLFAKKHGGEFILRIEDTDATRSTPEFETKVLDALKWCGLEWKEGPDIGGPYGPYRQSDRKPIYQPYAQELLDKGHAFRCFCTPARLEQMREAQRAAGKPPKYDGLCLSLTAEEVTSRTAAGEASVIRMKIPPEGSCDFTDGVYGDVSIPWDSVDMQVLIKADGMPTYHMANVIDDHLMKITHVARGEEWLASVPKHILLYRYFGWDQPVFMHLSLMRNADKSKLSKRKNPTSISYYSALGYIPEALMNFLGLFFIQIAEGEELLTMDELSEKFDPDNLSKAGAIFDIQKLDWLNGRWIREKLSEEEFQARVLAWAMENDRLKAGLRLSQTRISKLGELPDLAGFLLKSDLGLQPSDFAKIKSPPEEILEILNTVQPDLEKILEWNVETIEAELRAISDRMGKKLKVVVSPLFVAVSGSPRSLPLFDSMAILGRSVVRQRLKLAAQAVAALVGAK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_SHESW
Sequence: MIFQRTVQKMVKATGVGLHSGNKVTLSIMPAPVNTGIVLVRTDLSPAVAIPAKAEQVRETTMCTALVNDEGIRISTIEHLFAALAGLGIDNAVIEVDAPEIPIMDGSASPFVFLLQSAGIKEQAAPKKYLKIKRPVRVEDGDKWAELKPFKGFRVNFKIDFAHPEIARSQQHVVMDFSTSAFVKEISRARTFGFMRDIEYLRANNLALGGSMENAVVLDEYRVLNPDGLRYEDEFVKHKILDAFGDLYVAGHAILGEFTAYKTGHALNNQLVRALLAQQDAWELVSFEKEADVPVSFSVPSGAVFA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: H2BS1_ECHES
Sequence: MPSQKSPTKRSPTKRSPQKGGKGAKR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.1, sperm.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HDA10_HUMAN
Sequence: MGTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQDVTAVPMSPSSHSPEGRPPPLLPGGPVCKAAASAPSSLLDQPCLCPAPSVRTAVALTTPDITLVLPPDVIQQEASALREETEAWARPHESLAREEALTALGKLLYLLDGMLDGQVNSGIAATPASAAAATLDVAVRRGLSHGAQRLLCVALGQLDRPPDLAHDGRSLWLNIRGKEAAALSMFHVSTPLPVMTGGFLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAAMLRGLAGGRVLALLEENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKMLQCHPHLVA
What is the function of this protein?
Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine (PubMed:28516954).  Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine (PubMed:28516954).  Histone deacetylase activity has been observed in vitro (PubMed:11861901, PubMed:11726666, PubMed:11677242, PubMed:11739383).  Has also been shown to be involved in MSH2 deacetylation (PubMed:26221039).  The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak (PubMed:28516954).  May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells (PubMed:23801752, PubMed:29968769).  May play a role in homologous recombination (PubMed:21247901).  May promote DNA mismatch repair (PubMed:26221039).
What are the official names of this protein?
Polyamine deacetylase HDAC10, Histone deacetylase 10, HD10.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Excluded from nucleoli.
Protein: ENV_SFV3L
Sequence: MAPPMNLQQWLLWKKMNETHLALENISSLTEEQKQQVIIEIQQEEVIPTRMDRVKYLAYACCATSTRVMCWLFLICVLLIIVFVSCFVTVARIQWNRDINVFGPVIDWNVTHQATYQQLKAARLTRSLKVEHPHISYISINMSSIPQGVMYTPHPEPIILKERVLGISQVLMINSENIANVANLSQETKVLLTDMINEELQDLSNQMIDFELPLGDPRDQDQYIHHKCYQEFAHCYLVKYKKPSPWISEGIIVDQCPLPRIHDPNYYKYQPIWDYYLKIQNIRPQGWTSKSYYGTARMGSFYIPTFLRNNTVSHVLFCSDQLYGKWYNIENNIQENEQLLKTKLYNLTTYSKLKARALPKEWNNQGNARLFRSFNPLDVCNRPEAVLLLNTTYFTYSLWEGDCNYTTALIQNLTECRQPDRLKLKHPYACRFWRYKEGQEEVKCLGNEKKKCLYYSEYSSPEAQFDFGFLSYLNAFPGLKYIENQTVREPEYEVYSLYMECMNSAEKYGIDSVLFALKTFLNFTGTPVNEMSTARAFVGLTDPKFPPTYPNITKEQKRCNNLKRRKRSTNIEKLRSMGYSLTGAVQTLSQISDINDERLQQGVSLLRDHVVTLMEAALHDITIMEGMLAIQHVHTHLNHLKTILLMRKIDWTFIKSNWIKEQLQKTEDEMKIIRRTAKSLVYYVTQTSSSTTATSWEIGIYYEITIPKHIYLNNWQVINIGHLVESAGHLTLIRVKHPYEVINKECTYEQYLHLEDCISQDYVICDTVQIVSPCGNSTTTSDCPVTAEKVKEPYVQVSALKNGSYLVLTSRTDCSIPAYVPSIVTVNETVKCFGVEFHKPLYSESKVSFEPQVPHLKLRLPHLVGIIANLQNLEIEVTSTQESIKDQIERAKSQLLRLDIHEGDFPAWIQQLASATRDVWPAAARALQGIGNVLSNTAQGIFGTTVSILSYAKPILIGIGVILLIAFLFKIVSWLPGKKKRN
What is the function of this protein?
The leader peptide is a component of released, infectious virions and is required for particle budding.
What are the official names of this protein?
Envelope glycoprotein gp130, Env polyprotein.
What are the subcellular locations of this protein?
[Envelope glycoprotein gp130]: Host endoplasmic reticulum membrane. Note=The polyprotein has a highly unusual biosynthesis for a retroviral glycoprotein. It is translated as a full- length precursor protein into the rough endoplasmic reticulum and initially has a type III protein configuration with both its N and C- termini located intracytoplasmically (By similarity). SUBCELLULAR LOCATION: [Leader peptide]: Virion membrane; Single-pass type II membrane protein. Host endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Its N-terminus is located inside the viral particle. SUBCELLULAR LOCATION: [Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM.
Protein: HEMO_HUMAN
Sequence: MARVLGAPVALGLWSLCWSLAIATPLPPTSAHGNVAEGETKPDPDVTERCSDGWSFDATTLDDNGTMLFFKGEFVWKSHKWDRELISERWKNFPSPVDAAFRQGHNSVFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGECQAEGVLFFQGDREWFWDLATGTMKERSWPAVGNCSSALRWLGRYYCFQGNQFLRFDPVRGEVPPRYPRDVRDYFMPCPGRGHGHRNGTGHGNSTHHGPEYMRCSPHLVLSALTSDNHGATYAFSGTHYWRLDTSRDGWHSWPIAHQWPQGPSAVDAAFSWEEKLYLVQGTQVYVFLTKGGYTLVSGYPKRLEKEVGTPHGIILDSVDAAFICPGSSRLHIMAGRRLWWLDLKSGAQATWTELPWPHEKVDGALCMEKSLGPNSCSANGPGLYLIHGPNLYCYSDVEKLNAAKALPQPQNVTSLLGCTH
What is the function of this protein?
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
What are the official names of this protein?
Hemopexin, Beta-1B-glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the hemopexin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RRF_COXBR
Sequence: MINDIINDSKSRMEKSLGSLKTELAKLRTCRAHPSLLEHIKVDYYNVETPLSQVASIAIENPRTLSITPWEKNMVGPIEKAIQKADLGLNPATVGMVIRVPLPPLTEERRKELARVVREEAEHARVAIRNIRREANNDLKELMKEKEISEDEERRAQTAIQKLTDAQIAEVDKMASQKEADLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS13_RICCO
Sequence: MALSSISIFIHCLVDPLPRKQTSKTLPSNHIDFKSAFNVANWSINQTLVSPLSAQCIHLTDEDVRIKERRTRAFKHILRKEGEGSHEVLAMIDAIQRLGIDHHFQDEIDEILQRQYTIPSYYNDNDLHGLALRFRLLRQGGYNVSAGVFDKFKDKEGNFDQKLSDDIRGLMELYEASQLSIGAEDHILDEAGDYSHQLLSSWMTRLDDSQARIIKNTLDHPHHKNLARFRATNFNRYFHMANIEGWMNELQELAKIDFQMVQSQNQQEIFQVAGWWKDLGISKELKFVRNQPLKWYIWSMATLSDPSLSQQRIDLTKPISFIYIIDDIFDVQGSLDELTLFTEIVKRWDVEAVEQLPGYMRACFKALDSVTNEIGYKVYKQHGWNPVHSLRETWASLCKAFLVEARWFASGHLPAAEEYLQNGIVSSGVHVVLVHIFYLLGHGVTREGVDFIGNRPAIITSTATILRLWDDLGISKDENQDGHDGSYVECYVKEHKGSLVEIATKKVTVMISDAWKQLNQECLHPNPFSPNFTKSCLNLARMVPLMYSYDDNHRLPVLEYYTKSLLFESVSI
What is the function of this protein?
Probable sesquiterpene synthase.
What are the official names of this protein?
Probable terpene synthase 13, RcSeTPS13.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: TATA_BURL3
Sequence: MGGLSIWHWLIVLLIVALVFGTKKLRNIGNDLGSAVKGFKDGMKEGEAPADAQQLPRSGSVDVNAKETTRSDSNKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DLTC_STAXY
Sequence: MEFREQVLDLLTEVAENNVIKENPDVELFEEGIFDSFQTVGLLLEIQNKLDIEVSIMDFDRDEWATPNKIVEVLEELR
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_HAES1
Sequence: MHTFENHTPMMKQYLKIKAENPDVLLFYRMGDFYELFYDDAKKAAELLDISLTKRGQSAGQPVPMAGVPYHAIEGYLAKLVHLGESVAICEQVGEPVIAKGPVERQVVRIVTPGTVSDEALLPEKQDNLIATIYQEKTQFGLAVLDMTSGCFQISELQDAASLQAELQRIQPVELLYSEALEDKHLIEQFKGLRRRPLWEFELSTAIQLLNRQFGTKDLRGFGVEKAVLGLCAAGCLLQYAKETQRTALPHIQSISLLQNSDTVQIDASTRRNLELTQNLAGGTENTLAAILDKCVTPMGSRLLKRWIHQPIRNIEKLQCRQQHIQMLLQQNLVEELQPLLRQVGDMERILARVALRSARPRDLTRLRTALEQIPFIQHQLTKIPHFVAFSQQIADFSVQLALLQRAIIDNPPLLIRDGGVIAEGYNEELDEWRSLSEGATRYLKDLEQRERANTGIDTLKIGFNAVHGYYIQISQGQAHKAPLHYVRRQTLKNAERYIIPELKTYEEKVLKAKGASLALEKQLYDEIFDQLLPHLGDLQLASLTLAELDVLTNLAERAETLNYVQPQFSTQIGLQIMQGRHPVVEQVLKDPFIANPVELNQKRHLLIITGPNMGGKSTYMRQTALITLMAYIGSFVPAESAVIGPIDRIFTRIGASDDLASGRSTFMVEMTEMANILHQATEQSLVLIDEIGRGTSTYDGLSLAWACAEQLAQKIRSLTLFATHYFELTVLPEKIDGIHNVHLDAIEHNDNIAFMHSIQEGAASKSYGLAVAALAGVPQNVIKSAKQKLKQLETLSQQNSCQSQSVLTQVQGELTLMEEEENTSAVIETLKTLDPNELSPKQALECLYQLKKMLN
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FACOS_BOVIN
Sequence: MAGYQLWSPWTPLDESFQWLRHTTPTPSSKHPFRASPCFPHTPSDLEVQLCFQEVTLVLDSPFLEPGVSPKLPYHTSELRTMNNKKGLVRKPQPVRLSGVDSVFGRVITAQPPKWTGTFRVSEKSAFCKIISREHQWPTGLKEPQIQMTVTMCKQMLRSILLLYATYKKCTFALQHSK
What are the official names of this protein?
FANCD2 opposite strand protein, Fanconi anemia group D2 protein opposite strand transcript protein.
Protein: VKT1_AUSSU
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPEFCKLPADTGRCKGKFPAFYYHPVHRTCLEFIYGGCKGNPNNFKTIDECERTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor superbin-1, Superbinin-1.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: DGAT1_RAT
Sequence: MGDRGGAGSSRRRRTGSRVSVQGGSGPKVEEDEVREAAVSPDLGAGGDAPAPAPAPAHTRDKDRQTSVGDGHWELRCHRLQDSLFSSDSGFSNYRGILNWCVVMLILSNARLSLENLIKYGILVDPIQVVSLFLKDPYSWPAPCLIIASNIFIVATFQIEKRLSVGALTEQMGLLLHVVNLATIICFPAAVALLVESITPVGSLFALASYSIIFLKLSSYRDVNLWCRQRRVKAKAVSAGKKVSGAAAQNTVSYPDNLTYRDLYYFIFAPTLCYELNFPRSPRIRKRFLLRRVLEMLFFTQLQVGLIQQWMVPTIQNSMKPFKDMDYSRIIERLLKLAVPNHLIWLIFFYWLFHSCLNAVAELLQFGDREFYRDWWNAESVTYFWQNWNIPVHKWCIRHFYKPMLRLGSNKWMARTGVFWASAFFHEYLVSIPLRMFRLWAFTAMMAQVPLAWIVNRFFQGNYGNAAVWVTLIIGQPVAVLMYVHDYYVLNYDAPVGA
What is the function of this protein?
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.  Highly expressed in epithelial cells of the small intestine and its activity is essential for the absorption of dietary fats.  In liver, plays a role in esterifying exogenous fatty acids to glycerol, and is required to synthesize fat for storage (By similarity).  Also present in female mammary glands, where it produces fat in the milk (By similarity).  May be involved in VLDL (very low density lipoprotein) assembly (By similarity).  In contrast to DGAT2 it is not essential for survival (By similarity).  Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders (By similarity).  Exhibits additional acyltransferase activities, includin acyl CoA:monoacylglycerol acyltransferase (MGAT), wax monoester and wax diester synthases (By similarity).  Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG) (By similarity).
What are the official names of this protein?
Diacylglycerol O-acyltransferase 1, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase, Diglyceride acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FAD21_MYCTU
Sequence: MSDSSVLSLLRERAGLQPDDAAFTYIDYEQDWAGITETLTWSEVFRRTRIVAHEVRRHCTTGDRAVILAPQGLAYIAAFLGSMQAGAIAVPLSVPQIGSHDERVSAVLADASPSVILTTSAVAEAVAEHIHRPNTNNVGPIIEIDSLDLTGNSPSFRVKDLPSAAYLQYTSGSTRAPAGVMISHRNLQANFQQLMSNYFGDRNGVAPPDTTIVSWLPFYHDMGLVLGIIAPILGGYRSELTSPLAFLQRPARWLHSLANGSPSWSAAPNFAFELAVRKTTDADIEGLDLGNVLGITSGAERVHPNTLSRFCNRFAPYNFREDMIRPSYGLAEATLYVASRNSGDKPEVVYFEPDKLSTGSANRCEPKTGTPLLSYGMPTSPTVRIVDPDTCIECPAGTIGEIWVKGDNVAEGYWNKPDETRHTFGAMLVHPSAGTPDGSWLRTGDLGFLSEDEMFIVGRMKDMLIVYGRNHYPEDIESTVQEITGGRVAAISVPVDHTEKLVTVIELKLLGDSAGEAMDELDVIKNNVTAAISRSHGLNVADLVLVPPGSIPTTTSGKIRRAACVEQYRLQQFTRLDG
What are the official names of this protein?
Putative fatty-acid--CoA ligase FadD21, Acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RIMM_SALAR
Sequence: MMGKQLTAQVPAEPVVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQKADQWQQVQLESWKHHNQDLIIKLKGVDDRDAANLLTNCEIVVDSSQLPALEEGDYYWKDLMGCQVVTAEGYDLGKVIDMMETGSNDVLVIKANLKDAFGIKERLVPFLDGQVIKKVDLATRTIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EGLX_ASPFU
Sequence: MAPSSLLLSVGSLITSSLVSATALEARQSQTYQLAESWQGESFINDWNFFDGADPTNGYVTYVNQSFAKQSGLVKVTESGSFYMGVDYESTLNPNGAGRESVRIESKNYYTEGLYVIDIEHMPGSICGTWPAFWSVGKNWPNDGEIDIIEGVNLQKANKIVLHTSGSCDVSGSNDMTGTLSSSECGEASGTVGCVVKGTNGSSGDPFNESGGGVYAMEWTDTFIKIWFFPRSQIPASLASGNPDTSSFGTPMAHLQGSCDFAERFKAQKLIIDTTFCGDWAGNVFAESTCPMSDPSSPMQSCVNYVAQNPAAFKEAYWEINSIKIYQYGVSAASSAAVSQATASKVEGTRVSAQAANTATPTVPAPVETTTVPQPAQTNTVATSAADHATPSSAETTTVPAATGAPSVSATEGGDSELESTSTVYVTSTTTICPVAESSSAAAAGGKEDAPSNGTSGAEVAATSVAAAAPAAATSGHPGADAIANSAAATSTDAQSESATSRLTAGALSEIPTAPPEPVSQAVSTGSFDDSDTAQGDSEEQGSIASASVAPSTIPVPASSSAAALGGSSIASSFASSRLIPRPTGSSTAASATAIATWSPTAGESASGTAKESATLTTPSEVFFTPGLSNGANRMSVGLSGLIGVMFIAALA
What is the function of this protein?
Mixed-linked glucanase involved in the degradation of complex natural cellulosic substrates.
What are the official names of this protein?
Probable endo-1,3(4)-beta-glucanase AFUA_2G14360, Mixed-linked glucanase AFUA_2G14360.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: ARGC_HELMI
Sequence: MIRAAIVGATGYTGAELVRLLARHREVELVGLTSRQYADQPYANVYPHLSGQVDLACQSQDIDHITDMADVVFLALPHGLSVPWVAECVRKGKKVVDLGADFRLRRAAVYEQWYHVTHEAPELLAEAVYGLPELKREQIQKARIIANPGCYPTASLLSIAPLCGQGLIREDRLIIDAKSGVSGAGRNANLAIIYGEVNENVKAYNVAKHRHNPEIEQEVAERAGLDPDAMAITFTPHLMPMTRGILTTVYADLKEGVQPTSEEVRNLYRQFYAGEPFIHVMDEGVWPQTKWSYGSNHAYIGLTVEARTGRVIITTAIDNLVKGASGQAIQNMNILFGLPETTGIEAAGIYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_XYLFT
Sequence: MYSLFRPLLFTCDAERAHDISLRTLDIAYHSGALPLLTRHTRPLPTTAFGLNFPNPVGLAAGLDKNGTHIDALFALGFGFIEIGTTTPRPQAGNPKPRLFRLTQQQAVINRMGFNNLGVDALVRNVAGARRRNGPLGINIGKNKDTPNEQASNDYRYCLERVYALADYVTINLSSPNTAGLRALQEEQTLRRLIGELRETQETLAAKHGRHVPMLIKMAPDLSDSDIDAAARVLNEMSVDGVIATNTTVTRPLLRQHPLASEAGGLSGAPLLGQSTLVLRRLRTHLPETIDLIGVGGICCGADAGAKMAAGASLVQCYTGLIFKGPQLVGECVEAIRRRLEASSSGRENTQ
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YS12_CAEEL
Sequence: MKKITLLSGILFLIGYSDAEVFESQNVRVKRNDFTNNYGYGPFGIGPTNGGFDSYGFYRDKFYNSGLPPLYSFASYRNYYHEISFHKNKYGQPAPTDFETLQQERYGPYYDGVWGYADHSKNWFGKR
What are the official names of this protein?
Uncharacterized protein ZK1307.2.
Protein: YD050_YEAST
Sequence: MIMRYENQKKHKNHSLCSSSSSAMAEESSFDSSLPFFFLFLGNLGKFFFLWPLKDLDLPLKFLDFEASLCKSNCFFVKTLSFLPSYDKISLDSSSLEYDFKKASHSGIVLNSTKTVPLNFLFL
What are the official names of this protein?
Putative uncharacterized protein YDL050C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y7065_DROME
Sequence: MSFLPGEPVPPGFEEDVSRTAVIQKQIESYTAGPLIGTEYTIELHEPAQLRPNYFCVLCQTCSDGRNVFVHWTSQAHRTKYLQTHFQKAYKELQKLKRTPNSSGDLVTATGNLVKCIEKHFGRSRNLITATGDDFRRYRSKMCSQVRDSFHFDECAGSDFSEEAQRVIRELKPDESIKSSMKKNVDGTGDSNKQHDDGNIIALDAISSDDESFGGSTASVVPVPKGRQKNNLSEDAGGRSKNQSPPPAGGVNKTQHLPTPKELAIQASKISQERYKWEKFRCMLEIQLKQLRSDTEMYESNPEKHPDYPDEWKQFWNRRYKQLQEEKKCDPNQYDYKPEWISYWKDRRIVLFDIAVNKIKKDLKEKFKLGDEDEEKTLELMERYKIRVASPRRAPATTNSDNCRKTKPNFRNNRPIVATSKLPDAVIDISDDDVDSPPSRSRHSHKRRSISRSLSPKRGGRRAVRRSRSRSPRRSYNRGSTRSRSRSMRHRSRSPAHYRGRGRGREPASKERGSSSRDFGGRHSLQRERERSSEYYHRNEGYARSSRGYESVETFRVLDSRVYPEYKVTKTSSISPTASSNKEKEKEASEPIEEGPLTVVSVLRMLSAVEEHLGSLGPKALNLLSKALAMELVKPNAAEDLLRNEDNCVFLETTKEKLKGILIAEVLDDPQKVRVIKKLITNIAEIIYQATFKGTNDAVDVKVKANANPAPIQLPFDRNLVAPKLANALVLNGYNNVSTGDMNNLLHMLTLLMKTDKQRRQLDNNNGLKFEEIKVKLGLQNNPSPDDMGIDLDELMKEVEHQLHKESVDIVNKPTGAPAKVQAADTVGGSTGLESLTDSDLQTLLQNFKFLSNEEQVHLIGHLRKLEVQDPSRVDRLRKYVNLVELRGDGESCSDFLARVVKIGGASKAKPATKFKASVMGGRTSSAMAASSASATAPKVGHSMLSAQRPNLDRDMSSMPINKQRRGRNTPSIMLDDDDEEDDDYNFDDLVMKACDSNGSASAGGGGGVVGAGVHNKPGVPPIIGVESSPNALTFKPAAATKISLKDTENIIANLMGTLSKNGTSGGSPVGGNRNYMMNQQHGAPNAQNAPNLGQNPGQNLGQKQPGAGYSNAGYPGQQQQQQQQQQHGRNFGQEAQPLMSGLSGGPNANHYPNQQGYGGYHPFAGNGVQQNYGGMVPPGPGGYVGPPPNPWASNVPPQPPFNQMPQNFMGAQQQQQQQQPHFNNMFGGRH
What are the official names of this protein?
Uncharacterized protein CG7065.