PharMolix/UniProtQA huggingface dataset:
Protein: EFNMT_MOUSE
Sequence: MNLLPKSSKEFGSADYWEKFFQQRGKTAFEWYGTYLELCEVLHKYIKPKEKVLVIGCGNSELSEQLYDVGYQDIVNIDISEVVIKQMKERNGSRRPHMSFLKMDMTQLEFPDATFQVVLDKGTLDAVLTDEEEVTLRQVDRMLAEVGRVLQVGGRYLCISLAQAHILKKAVGHFSREGWMVRAHQVASSQDRVSEAEPRFSLPVFAFVMTKFRPVPGSALQIFELCTQEQGKPVRLESADQLAEAVRERQYYAWLCSQLRRKAGLGSVSLDLCSGDTGEPRYTLHVVDNPAVKPSRDNHFAIFIIPQGRETEWLFGMEEGRKQLAASAGFRRLVTVALHRGQRYAGMESIQAELSARVMELAPAGLPPQQQVPFLSVGGDIGVRTVQHQDHSALSGDYVIEDVQGEDRWYFRRLIFLSNRNVVQSEARLLKDTSHRAQKKRKKDRKKQRPADTSEDFPPAPGQSIDKSYLCCEHHKAMVAGLALLRNPELLLETPLTLLVVGLGGGSLPLFVHDHFPKSRIDAVEIDPTMLEVATQWFGFSQSDRMKVHIADGLDYITSLAGEAPPHYDVIMFDVDSKDPTLGMSCPPPAFVDQVFLQKVKSILCHDGVFILNLVCRDVRLKDSVLAGLKAAFPLLYVRRIEGEVNEILFCQLHPEQKLATPELLEMAQVLERTLRKPGQGWDDTYVLSDMLKTVKIV
What is the function of this protein?
Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation (By similarity).  Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2' (By similarity).  Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55' (By similarity).  Has no activity towards core histones H2A, H2B, H3 and H4 (By similarity).  Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6 (By similarity).
What are the official names of this protein?
eEF1A lysine and N-terminal methyltransferase, eEF1A-KNMT, Methyltransferase-like protein 13.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: GYS1_HUMAN
Sequence: MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGDNYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVGASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKPHVVAHFHEWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYHRYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQTVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVGSLPDMNKMLDKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPEFLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKYLGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSRHSSPHQSEDEEDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASCTSSTSGSKRNSVDTATSSSLSTPSEPLSPTSSLGEERN
What is the function of this protein?
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
What are the official names of this protein?
Glycogen [starch] synthase, muscle.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 3 family.
Protein: MUKF_SALPC
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAAEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRIMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDDPWALTYANADRLLDMRDEEMALRDDEVTGELPPDLEYEEFNEIREQLAAIIEEQLAIYKTRQTPLDLGLVVREYLAQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: RL23_CERS1
Sequence: MTAKPEHYDVIRKPVITEKATMTSEANGVVFAVAMEATKPQIKEAVEAIFNVKVKAVNTVVTKGKTKKFKGRPGVRSDRKKAYVTLEEGNTIDVSTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y2058_ARCFU
Sequence: MPKKLVLVIDRDDDLGQKAGISSPVIGRDNIVSAAVRLGTADPEDSDVNAMFAAIKIYDELKGRGEDVEVVVVCGDRSVGVVSDSKIAEQLDRVVLNLRPSSAIVVTDGSEDEFVLPIISSRVKIDSVHRVVVRQSRTIESTYFLIRRMLNDPKIARITLAPLGMIFLVYSIFLVMQHPEWGLGGIIFFLGVYFMVKAYGWEQNIANLLETVRVSLVEGRLSFIFYVTSAILLIISIVNGFNAAVNIADAAQAISSFIFYSTWWFVLSGIFALLARAADAYAEKRRVSKYFTIIFLLIAFGLIVWASAAYVLNPEAPNALQNLAGAIVGAILIAAIGVFTLKRL
What are the official names of this protein?
Uncharacterized protein AF_2058.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1032.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRPE2_MOUSE
Sequence: MAARSLWAVQRLQRLLASGAMSESRGWLHPFSTATQRTAGEDCSSEDPPDGLGPSLAEQALRLKAVKLEKEVQDLTLRYQRAVADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADILEKTAKCCSEGAEPEDHRRTLEKVFQGLSLLEARLKSVFTKHGLEKMTPIGDKYDPHEHELICHMPAGVGVQPGTVALVRQDGYKLHGRTIRLAQVEVAVESQRRL
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.  Stimulates ATPase activity of mt-HSP70.  May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
What are the official names of this protein?
GrpE protein homolog 2, mitochondrial, Mt-GrpE#2.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y277_SULAC
Sequence: MEFTPLAFESLGVRSQATLVETKDVRILIDPAVSLAPRRFGLPPHQIEVDRLTELAKKIYEEAKIADIIIITHYHYDHHDPGYVIPLDIYQNKTVYIKDPQNFINPSQKFRRAPRFIKTITGKPKTMESADGKVVKYGSTTIQFSKAVPHGADERLGYVIQVAINDKDSTILFTSDIEGAPKNSHIDFIKSVRPNFLIIDGPLSYLLGRALSQDELDTEIKNMEEVVRNGLQYAIIDHHVLRDPNYESVLKPVKEVANSVGCKVISASEYLREPPQLLEAKRRELFQRDNRPAKIPRGLAKLLSAGEGG
What are the official names of this protein?
UPF0282 protein Saci_0277.
What is the protein family that this protein belongs to?
Belongs to the UPF0282 family.
Protein: SFGH2_ECOUT
Sequence: MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPPVLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEQVANDDGYDLGQGAGFYLNATQPPWATHYRMYDYLRDELPALIQSQFNVSDRCAISGHSMGGHGALIMALKNPGKYTSVSAFAPIVNPCSVPWGIKAFSTYLGEDKNAWLEWDSCALMYASNAQDAIPTLIDQGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYLLK
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase YeiG, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: RK2_NUPAD
Sequence: MAIHLYKTSTPSTRKGAVDSQVKSNPRTNLIYGQHRCGKGRNARGIITARHRGGGHKRLYRKIDFRRNEKDISGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPISMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLISKNCSATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPTTPWGYPALGRRSRKRNKYSDIFILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y793_STRP7
Sequence: MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVPTQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR
What are the official names of this protein?
UPF0298 protein SP70585_0793.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTP23_STYPL
Sequence: WMMIVEQKCRVIVMLAKCFEAGKKKCQKYWPDSEETKTFGRVKVFNAEEVKYCGFLRRRFHIESFDEMMSVEVFQYQYINWPDHSVPNTTSNLVRMHKYVIQCLEEIGGDAPMVV
What are the official names of this protein?
Tyrosine-protein phosphatase 23.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: NU4LM_MACMU
Sequence: MTLTYMNIMLAFAISLLGMLTYRSHLVASLLCLEGMMMSLFIMATLIASNTHFPLINIMPIILLVFAACETAVGLALLISISNTYGLDYVHNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PTH_SHEB2
Sequence: MSEIKLIVGLANPGAEYAHTRHNAGAWYVLELARICGVTLVADSKYFGLTARAVLHGKDVRLLIPTTYMNLSGKAVGALANFFRITPEEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIIAKLANDKNFYRLRLGIGHPGDKNQVSGYVLGKAPAKEQELIDAAIDEAVRSTEILFKQDMVKAMNRLHSFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_STACT
Sequence: MKPGEIIVKKTEIEINKGTDDSETVITVKNIGDRPIQVGSHYHFFEANTGLKFDREKAYGKHLDIPAGAAVRFEPGDEKKVQLVEYNGRRRIYGFRGLVDGAIDEERVFRVENGHPNAGVKNDEGKQNANKESGDNR
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_CAMLR
Sequence: MANHKSAEKRARQTIKRTERNRFYRTRLKNITKAVREAAANNDKEAAANALKIANKSIHAMVSRGFLKKQTASRRVSRLALLVNKIA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: TPX_CLOAB
Sequence: MKVKFKGKEVTLEGTEIKVGDTFPDFVAVNSSLEPVMLKNTNRVRVFLAVPSVDTPVCDLEVKTFNARASEIDGVSIYTISMDLPFAQSRWCGAEGIKNVTTLSDYRDRAFGKNTGTYIKELGLLARAVFVVDSSNKVTYANYLEEVSGYPNYDEVLQAAQAAK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: NIFU_TRIAZ
Sequence: MWDYTDKVLELFYDPKNQGVIEDNGEPGVKVATGEVGSIACGDALRLHIKVEVESDKIVDSRFQTFGCTSAIASSSALTEMIKGLTLDEALKVSNKDIADYLGGLPEAKMHCSVMGQEALEAAIYNYRGIPLATHDDEDEGALVCTCFGVSENKVRRIVIENDLTSAEQVTNYIKAGGGCGSCLAKIDDIIKDVKENKAATNLNNKGGSKPTNIPNSGQKRPLTNVQKIALIQKVLDEEVRPVLIADGGDVELYDVDGDIVKVVLQGACGSCSSSTATLKIAIESRLRDRINPSLVVEAV
What is the function of this protein?
May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
What are the official names of this protein?
Nitrogen fixation protein NifU.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
Protein: YIDD_LISIN
Sequence: MKKMLIGGIRLYQKYISRFTPATCRFYPTCSAYGIEAIETHGALKGSYLAIRRISKCHPFHKGGLDFVPPKKDKNDDSGHTCKAHHHH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ISPH_RHIL3
Sequence: MNIAAKPPLTIRLCGPRGFCAGVDRAIQIVVLALKSYGAPVYVRHEIVHNRYVVEGLEAKGAVFVEELDEIPAEHRAQPVVFSAHGVPKSVPEDAASRNLFYLDATCPLVSKVHKQAMRHNRLGRHVVLIGHAGHPEVIGTMGQLPEGSVSLIETIEDADAYVPVDPDNLGYVTQTTLSVDDTAGVITRLHERFPNLTAPAADSICYATTNRQEVVKQAAPGCDLFIIVGAPNSSNSKRLVEVALRAGAKKSILVQRAAELDWDEIGAISTLGLSAGASAPEVIVNEIIEAFRARFDARVELAETVQETENFLVNRELRNIELTAADMAFVNG
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: GLYR1_CHICK
Sequence: MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHLHKEEMIKINKGKRFQQAVDAVEEFLRKTKGKDQASSHNSSEEKNRRNSSEERGKQSAREEKRKASLSEGKLKKGTGEGKKRVSSVSSERGSKSPLKRAQDQSPRKRGRPPKDEKDLTIPESSTVKRVMTGTVAGFKWPPSVSEPVKDSDPHFHHFLLSQTEKPAVCYQAITKKLKVCEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDSVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH
What is the function of this protein?
Cytokine-like nuclear factor with chromatin gene reader activity involved in chromatin modification and regulation of gene expression.  Acts as a nucleosome-destabilizing factor that is recruited to genes during transcriptional activation.  Recognizes and binds histone H3 without a preference for specific epigenetic markers and also binds DNA.  Interacts with KDM1B and promotes its histone demethylase activity by facilitating the capture of H3 tails, they form a multifunctional enzyme complex that modifies transcribed chromatin and facilitates Pol II transcription through nucleosomes.
What are the official names of this protein?
Cytokine-like nuclear factor N-PAC, NPAC, Glyoxylate reductase 1 homolog, Nuclear protein NP60, Putative oxidoreductase GLYR1.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. NP60 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Found in actively RNAPolII-transcribed gene bodies.
Protein: RL25_DEIDV
Sequence: MELNAKPRKSQEKLAEGLIPAVAYNKDNNISFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKTVQMDKRRRTPIHVDFYMVTYGEPIEVSVPVHTTGKSQGEIMGGLVDIVLHNLSIVAPGPRRIPQELTVDVSRLNIGDHITAGDVKLPEGCTLAVAADSVVISVLPPRMTADEAAAETQAAQVAGLVAAGELSEEAAAAVLEGDASIEEIKAEAHAAEGTQAEGSTEEGQQQ
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RECF_PSEPU
Sequence: MSLRRIMVTAVRNLHPVTLLPSPRINILYGANGSGKTSVLEAVHLLGLARSFRSTRLNPVIQYEQAACTVFGEVQLTEGGTSNLGVSRERQGEFTIRIDGQNARQAQLAELLPLQLINPDSFRLLEGAPKIRRQFLDWGVFHVEPRFLPAWQRLQKALRQRNSWLRHGTLDPASQAAWDRELCLRSAEIDEYRRNYIKALKPVFERTLSELVELDGLTLSYYRGWDKDRELQEVLASSLLRDQQMGHTQAGPQRADLRLRLAGNNAADILSRGQQKLVGMRIIAQGHLVSQARRGHCIYLVDDLPSELDDQHRRALCRLLEELRCQVFITCVDHELLREGWQTETPVALFHVEQGRITQTHDHRE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_METBF
Sequence: MLPEEDLKIIKKELGREPTLVEQGCFLNLWSEHCSYRSSAPLLKTFTSKGENVIIGPGDDAAIIKFDDGYVLAIGMESHNHPSYVDPYNGAATGIGGIVRDIISMGARPIALMDPLYFGPLDTPKNMFLFEQIIKGIAGYGNCIGVPVVNGETFFDRRYSGNPLVNVVAVGLCREEEVITARSQKAGNKLVLAGSSTGKDGLGGASFASRDLSESAEAEDRPSVQVGDPYTEKLVIEMTLEAMEKGYIKSCKDLGAAGLGGASAELAAKGGLGAHITADAVTQREPNMNAYEILLAESQERMVFEVAPEDVDAVLALVAKYDLNGAVVGYLTEKPNYTVEFKGEVVVDIPIDFLTGGAPTCEKSSVAPIPQVEEGKAPKTPEDLKAAFLKVISSYNIASKEWIYRQYDHEVQLRTVIKPGEDAGVLKITDKKGLVLSCGCQPRATLLDPYNGGKNVVIENAMNLAVKGADGLAIVNCLNFGNPDRPEIYWQLKNSVLGLGDGARELSIPVVGGNVSLYNESDEFKTAILPTPSIGIIGKVNFETPLPSSFFAKSGDAIILVGETTADMGGSEYYACFEALNAGKVPSVPKNAPEIIKAVIEAARSGKLSSAHDLSLGGIAAGLARMCRNSGAKVDLSEVSELKAEELLFSEAPARALLATSEPEAVLEILKDVPHMVIGKVEGNSLEVKGKDFEISLSLKEISDAYSSLTRFMMR
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLH3_FORAG
Sequence: MTTKNNKQLKSVLFMFLLLIGAYVKAQEKNVSGTVTSSEDGMMLPGVNIIVKGTASGTTSDFDGNYNIEVPDSNAILQFNYLGFVTQEIKVGAQTNISVVLQVDQNELEEIVVIGYGTVKKSDVSGSVSSVKSAELTAYPTVSAEQALQGRAAGVQVQSNNGGEPGAPIKVRIRGGTSINASSDALIVVDGFVGASMPAPQDIASMEVLKDASATAIYGSRGANGVIMVTTKKGTSSKPTLELNTSYSLQHVNNTIDLLDADEFATYRQAYSENYVQGPANTDWQDEIYTTGSISNTQLAFSGGSDNSKYYISGNYFAQDGVVINSNLERFTILSNVDVDITKRFKVGLNVFGGRSTKDGVSTQAQTGGTGGGDVISSAYRFAPDLGIYNADGTYTINSLGDDIDNPYALATESVDERKADTYRANFYAAYEFIDGLEFKTTFGFSSENTQIGKFKPTTILAGAGVGGEATFEYRNTTNTLSENYLTYNKSFGAHNLSLLGGYSYQKVQNEGAFAGARSFVTNEVSYRNLEGGAVTMQPSSYLNETELVSVFGRVNYEYASKYIFTFTARRDGSSNFSKNNKYAFFPSGAIAWNMAKENFLKDSNTITTWKWRASYGATGNPSISPYETLAKFSSVYAVVGDQQVNGVVLTDFANDNLKWETSKQLDLGLDVALFDNRLELSFDYYTIKTEDLLFPRPLPEYSGVSSQIQNIGELENKGYEFSINSRNITNQDFTWSTAFNFSRNKNKMVKLPDGDDLFIDSAPGHFLQRQTQILREGEAIGSFYGYEYKGVYQGGNFPEGTATLSGDSDPGGELFADLDGNGEISTADRKIIGDPTPDFTMGFNNDLRYKNFDMNLFFQASVGGEILNYTLLELGSGAANSTADMVNAWSPTNTNTDVPRPAVREKRITSRYVYDGSYVRLKNLSFGYNLPESFLGKTGLQTVRLYVSGQNLLTFTDYPGADPEANYRNDNNQRSNTNIGLDYGSYPNVRTFTMGLNMKF
What is the function of this protein?
TonB-dependent receptor probably involved in ulvan degradation (Probable).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).  The TonB-dependent receptor may mediate transport of ulvan oligosaccharides from the surface of the outer membrane to the periplasm for subsequent degradation (By similarity).
What are the official names of this protein?
TonB-dependent receptor P3, P3_TBDR, Polysaccharide utilization locus H protein P3, PUL H protein P3.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: FLIQ_BUCAI
Sequence: MTSEYVMELFYNAMKVALIIASPLLLAALISGLIISILQAATQVNEQTLSFIPKIISVLGVISILGPWMLGVMLDYMHNLFNNIILIIK
What is the function of this protein?
Role in flagellar biosynthesis.
What are the official names of this protein?
Flagellar biosynthetic protein FliQ.
What is the protein family that this protein belongs to?
Belongs to the FliQ/MopD/SpaQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: COBT_SHIF8
Sequence: MQIIADLLNTIPAINSAAMSRAQRHVDGLFKPVGSLGKLEALAIQLAGMPGVNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYTRELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNRDMRIGEGIVQALAMSIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: CSGC_SALEN
Sequence: MHTLLLLAALSNQITFTTTQQGDIYTVIPQVTLNEPCVCQVQILSVRDGVGGQSHTQQKQTLSLPANQPIELSRLSVNISSEDSVKIIVTVSDGQSLHLSQQWPPSAQ
What is the function of this protein?
Plays a role in the extracellular assembly of CsgA (also known as AgfA, AC P0A1E7) into thin aggregative fimbriae (Tafi) fibers.  Assembly may also require CsgE (AgfE).  Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway.
What are the official names of this protein?
Curli assembly protein CsgC.
What is the protein family that this protein belongs to?
Belongs to the CsgC/AgfC family.
What are the subcellular locations of this protein?
Periplasm. Note=Upon overexpression; a small amount is also seen in the cytoplasm.
Protein: COAX_BACMK
Sequence: MIFVLDVGNTNAVLGVFEEGELRQHWRMETDRHKTEDEYGMLVKQLLEHEGLSFEDVKGIIVSSVVPPIMFALERMCEKYFKIKPLVVGPGIKTGLNIKYENPREVGADRIVNAVAGIHLYGSPLIIVDFGTATTYCYINEEKHYMGGVITPGIMISAEALYSRAAKLPRIEITKPGSVIGKNTVSAMQSGILYGYVGQVEGIVKRMKEEAKQEPKVIATGGLAKLISEESNVIDIVDPFLTLKGLYMLYERNANLQHEKGE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARHG9_BOVIN
Sequence: MELDQVGWRRSRKLCTDNLDQGSKTLETCKNIGGYFKPQGPGTEHINELITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVSKQKGVNSARSVPPSYPPPQDPLNQGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK
What is the function of this protein?
Acts as guanine nucleotide exchange factor (GEF) for CDC42.  Promotes formation of GPHN clusters (By similarity).
What are the official names of this protein?
Rho guanine nucleotide exchange factor 9, Collybistin, Rac/Cdc42 guanine nucleotide exchange factor 9.
What are the subcellular locations of this protein?
Cytoplasm. Postsynaptic density.