PharMolix/UniProtQA huggingface dataset:
Protein: NRDR_BACCN
Sequence: MRCPSCFHNGTRVLDSRPVDEGRSIRRRRECESCLNRFTTFERVEEPPLIVVKKEGTREEFNKEKILRGLIKACEKRPVSLKQLEEVTQNVERELRNLGISEVKSDMIGEIVMEALRDIDDVAYVRFASVYRQFKDLNVFIEELKDILQKERE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SLX4_PHANO
Sequence: MPASPLPALSPPASPRRNTSGASALGSRKADIPPDAIRGFATVGSLVRSEHFAQHFDDDIAGKDQEQSRKKSPEDVGNIAATKKKPGKRAATTSTADGEAKPKPKPRARKPKAADEEAVIIDPELRLPAAKVSPFFAAEGAPAAIEPSDEPVVDVPKLTKAGKPRKPRAKKENVGGEEAVPKPKRTRVTKPKAAKAKAGGKSQEEACVESAHFRKSEDTGDETVAGVLATRKSATTENVGSGEASIWDVPQSPKPKKKRAPKKPPPDPVINNLELDEAVSRRRDWTPPRDTAIPSPFTDSVGKENKQIEPDADNGGFTHMISNFAYAQALPAQVASTVADSATGTMAATKRRRIELLDVPGNQTTSRNSSPEKGKAPKKKPRTITDIATEQYQHRAAQLDQSDVASDFFQSHTAVTKVPLNDASLPNGDAPTKKPPRKRSTSKPASEKEKVGSKARSKKASTKAAAKPKHIAEKLLSPGSALMRMNKQDILFGTSSQLALEEPPTLVRQLQHALKESEVEADLSSNGMIAPPPRWPKLDKVVGKRSLWDASSRDVEGGMLEHMEDVYIPEFDRTQDFPLLMDGTNDQPDGAPPSFADIDDFEPAPPVIISSDGPTPPPTTSRTSQRKANDEPDHVMEGPVFEDIDDFDFQPPPSNQNVEFQDSFADDDEILHTSVQSSTHPPPRLRPPATSDPMNGSSKKPRGCPAKSQSAIATSGSPAVAKEPKRTKGKEVKSAPAPPTTPAKGSGRFIDIDEILDSDDEALQALSPTPPRIHNFENSQPLPLYSVSPTRAKKPKADSSVDSKIVPVHIIPTAHLEWLNLKNSIFPSITSHIRSLPSTRDPSKPSWHEKILMYDPIVLEDFTAYLNAKTSLRTWRRATKIQSKAWNKAQKSIGAQEIGVVEGGGNVLAVEKELEAWQVQSWCESMSVCCIWGEGRGKGGVRKGFY
What is the function of this protein?
Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHLC_STAAU
Sequence: MVKKTKSNSLKKVATLALANLLLVGALTDNSAKAESKKDDTDLKLVSHNVYMLSTVLYPNWGQYKRADLIGQSSYIKNNDVVIFNEAFDNGASDKLLSNVKKEYPYQTPVLGRSQSGWDKTEGSYSSTVAEDGGVAIVSKYPIKEKIQHVFKSGCGFDNDSNKGFVYTKIEKNGKNVHVIGTHTQSEDSRCGAGHDRKIRAEQMKEISDFVKKKNIPKDETVYIGGDLNVNKGTPEFKDMLKNLNVNDVLYAGHNSTWDPQSNSIAKYNYPNGKPEHLDYIFTDKDHKQPKQLVNEVVTEKPKPWDVYAFPYYYVYNDFSDHYPIKAYSK
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture.  Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins.  Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity).
What are the official names of this protein?
Phospholipase C, Beta-hemolysin, Beta-toxin, Sphingomyelinase, SMase.
What is the protein family that this protein belongs to?
Belongs to the neutral sphingomyelinase family.
Protein: ENO_ROSDO
Sequence: MSTIIDIHAREILDSRGNPTVEVDVILEDGTMGRAAVPSGASTGAYEAVERRDGDKTRYMGKGVLEACAAVNGEIADALVGLDATEQVDIDASMIELDGTANKSRLGANAILGVSLAAAKAAADYCTQPLYRYVGGTSARVLPVPMMNIINGGEHADNPIDIQEFMIMPVAADNIRDAVRMGSEVFHTLKKELSAAGLSTGIGDEGGFAPNINSTRDALDFILKSIEKAGYKPGEEIYLALDCAATEYFKNGKYELSGEGKSLTSEENVAYLAALVADYPIISIEDAMSEDDWDGWKALTDALGHKVQLVGDDLFVTNPERLATGIERGSANSMLVKVNQIGTLTETLKAVDMAHRAGFTNVMSHRSGETEDATIADLAVATNCGQIKTGSLARSDRLAKYNQLIRIEEALGETAEYAGRSILR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: HUTI_BACSU
Sequence: MPKQIDTILINIGQLLTMESSGPRAGKSMQDLHVIEDAVVGIHEQKIVFAGQKGAEAGYEADEIIDCSGRLVTPGLVDPHTHLVFGGSREKEMNLKLQGISYLDILAQGGGILSTVKDTRAASEEELLQKAHFHLQRMLSYGTTTAEVKSGYGLEKETELKQLRVAKKLHESQPVDLVSTFMGAHAIPPEYQNDPDDFLDQMLSLLPEIKEQELASFADIFTETGVFTVSQSRRYLQKAAEAGFGLKIHADEIDPLGGAELAGKLKAVSADHLVGTSDEGIKKLAEAGTIAVLLPGTTFYLGKSTYARARAMIDEGVCVSLATDFNPGSSPTENIQLIMSIAALHLKMTAEEIWHAVTVNAAYAIGKGEEAGQLKAGRSADLVIWQAPNYMYIPYHYGVNHVHQVMKNGTIVVNREGAILG
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5454_DICDI
Sequence: METIICKGCNRIYNEPLSLSCGDILCRNCLCEKCKICSQTITWAIPNKTVKSYIDSLIVKNCSNHKNQENDTNSKKSTSYCLQCESFNNLDQITSIHTYH
What are the official names of this protein?
Uncharacterized protein DDB_G0291640.
Protein: TGT_SHIF8
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSIYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RS16_STRPC
Sequence: MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLVAENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: DIAA_SALSV
Sequence: MLERIKVCFTESIQTQIAAAEALPDAISRAAMTLVHSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHHSARIQEMHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: RTC5_YEAST
Sequence: MGQSSSISSSNEEGSSHSKKFTNSKDILAYFNNKAQQQVTIPELVSFKGNLQIEDLNTPISHKALCNSLYFPQNHAMIVGIVTNMLRVLSNFPLMKSSYEPITGYGLLKCILLLNRARCAKFLKTKSYDQLKLLFISLSLQKTDKEELSEESENDGNKELTIKQIITGFDDVDTEMLCIPADFMLQFLTWLLILTVDCPTTNSKLDNTETHDQWGNFKVSALNLLRTMNPDVVGDIESHSITFQQFSTAIRTVMPNLLKPLENLMEHFFYLQHDLVDHDTNLSSIQDSKVMTPALLAQLSTGLPKELFIHKLQSLYIGRKSGFSMRSLQAKVFKWMAPSILVVSGMRITNSEEYAAEKNPRYRHFLEEFPKLKESDQMMDASHLNKRKTTFAVYIDDPWKVTNKDYFGDLNTRIIEISPRQDIYKVNQKGTIYFNTIGGGIGIGDKQPLIKPASKRYIPGNVSLTFDSTLEFAVFRNTGYGGSLDPGLLSMERKEENSPYELHFLIQDVEVWGCGGEKELEEQIKQLEWEEAESKRRQQINLRSLGEDRALLEMAGLVGQHQGGGSM
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_BORGP
Sequence: MDRYFFLQDATTVARLLLGNLLIRKINKKEIVARIVETEAYMGIADSACHSYGGKRTNRTNAMYSIGGYSYVYMIYGMHYMFNVVTADKNNPQAVLIRSIEPISPLLGKKSALTNGPGKLTKFLNIDLTFNKVDLIGNNELFLQRDLNLDFNIVCSKRININYAQEDDINKLWRFYIKDNKFVSRR
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: CAIA_SALPB
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLEAGFVTVAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRKNGKVYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKAGIKVNKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLLEAAWKADNGTITSGDAAMCKYFCANAAFEVVDTAMQVLGGVGIAGNHRITRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_DESAH
Sequence: MPRSLKKGPYIAQELLNKVLVAQETRSKKVIKTWSRRSTIFPDMVGLTLAVHNGKKFVPVFVTENMVGHKLGEFSPTRTFYGHAGDKKAKMR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NIKR_BRUSI
Sequence: MQRITITIDDDLMAALDRMIEIKGYQNRSEALRDLARTGLQQASLEEGQMEACVGVLSYTYDHSARDLSKKLTNTHHDHHNISVASMHVHLDHDRCLEVSILKGKTDDVRHFADHVKAERHVTHGTLAVLPL
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: FENR_STAHJ
Sequence: MQDVTIIGGGPAGLFASFYAGLRGMSVRIIDVQDKLGGKMQIYPEKIIWDIGGVAPKPCNEIIKDMINQGLHFNPKVNLNERVTDIRKIAERHFEVETDSGQIYESKAVIFAVGGGIINPKPLQIKDAERYRLTNLHYVVQSFSKFKGKDILISGGGNTALDWARDLANIANSITLVYRKSDIKGYEAMISVLKALNVNLLPKTQIKELIGDNKCECIKEVKLENIETGEVTTQAFDDVIVSHGFDHENPLLKDCTSKLDLYDEYRVKGFGNTTTNIPGIFACGDIVHHDAKVHLIASAFSDAGNAANLAKTYINPDAYKEGYVSSHNDVFKESNKKVINQYI
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: RBL1B_HYDCU
Sequence: MASKTFDAGVQDYQLTYWTPDYTPLDTDLLACFKVVPQDGVPREEAAAAVAAESSTGTWTTVWTDLLTDMEFYKGRCYRIEDVPGDKNAFYAFIAYPLDLFEEGSVVNVLTSLVGNVFGFKAVRSLRLEDLRFPIAFIKTCGGPPAGIQVERDKLNKYGRPMLGCTIKPKLGLSAKNYGRAVYECLRGGLDLTKDDENINSQPFQRWQNRFEFVADAVDKATAETGERKGHYLNVTAGTVEEMMKRAEFAKELGQPIIMHDFLTAGFTANTTLANWCRDNGMLLHIHRAMHAVIDRNPNHGIHFRVLAKCLRLSGGDHLHTGTVVGKLEGDRASTLGFVDQLREAFVPEDRSRGVFFDQDWGSMPGVMAVASGGIHVWHMPALVNIFGDDSVLQFGGGTQGHPGGNAAGAAANRVALEACVKARNEGRDLEREGGDILRDAARNSKELAVALDTWKEIKFEFDTVDKLDVG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site (By similarity).  Replacing the endogenous type I ccbLS genes in H. neapolitanus with this carboxysomally targeted enzyme reconstitutes RuBisCO with about 25% of normal activity; the active enzyme is targeted to carboxysomes (PubMed:18974784).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain 2, RuBisCO large subunit 2, Carboxysomal form I RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.
Protein: NOP10_SULIA
Sequence: MKWKMKKCPKDNTYTFKDICPVCGSKTMIPHPSRFSPEDKYVKYRIELKKGVKLNC
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: TR1L1_XENLA
Sequence: MGIRKKSSKTPPVLSHEFIIQNHADIVSCLAMVFLLGLMFEITAKAAVMFVTLQYNVTIPVEGVLGEQASLYHYGIKDMATVFFYMLVAIILHAVIQEYILDKINRRMHFSKTKHSKFNESGQLSAFYLFSCIWGASIIVSENYFSDPISLWKGYPHTYFPFQMKFFYISQLAYWFHAFPELYFQKTKKEDIPRQLVYIGLYLFHILGAYVLNLNRLGLVLLVLHYFVEFLFHMSRLFYFSNEKYQKGFTVWALLFVLGRLLTLILCVLTVGFGLARAENQELDLSNGNFNILAIRISVLASICITQAFMMWKFINFQLRRWREHSSPQPSSQRKKTTSAKGKASRKEKENGVNGTVTSNGADSPRSRKEKHS
What is the function of this protein?
Stimulatory or required for the translocation of secretory proteins across the ER membrane.
What are the official names of this protein?
Translocating chain-associated membrane protein 1-like 1.
What is the protein family that this protein belongs to?
Belongs to the TRAM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y1710_STAAM
Sequence: MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQLREKYQN
What are the official names of this protein?
Putative universal stress protein SAV1710.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_STAA2
Sequence: MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKLKDDDTIVLVGFGGGLTWGAMTIKWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_CHLP8
Sequence: MAVQQKIRIKLKSYDHSLVDKWALKIIDVVKQTDAIIFGPIPLPTKTHVYTVNRSPHVDKKSREQFAFSSHKRLIEIINPTARTIDMLMKLELPSGVDVEIKS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GATB_METST
Sequence: MMCGLEIHVQLNTNSKLFCSCPTNYQSAPNNTNICPVCLNQPGAKPYPPNQAALDNAIKVALMLGCEISNEVIYFMRKHYDYPDLSSGYQRTSVPVGIKGELNGVRIHEIHVEEDPGQYKPDRGTVDFNRSGIPLIEIVTEPDMKSPEEARNFLNELIRVLNYSGSARGEGTMRADVNISIEGGKRAEVKNVNSIRGAYKVLKFELIRQKNILRRGGEVQQETRAYLESQMITVPMRLKEDADDYRYIPDPDLPPLKIDPAHVEEIRQNMPEPAHLKTERFVEEYGIDKKDAKVLTSELELADAFEEVCKEVDANVAARLMRDELKRVLHYNKIQYAESKITPSDIVELINLIESKQVTPEAAHKLIEQMPGNDKTPTEIGNEMDIIGVVEDDAIVNAINQAIEENPNAVEDYKNGKDNAVNFLVGQVMRLTRGKANAGETNKMIKEKLDQL
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PRF02_KALTU
Sequence: MSWQAYVDEHLMCNIEDTGNHLTSSAIVGVDGSIWAQSSNFPQVKPQEIEAINKEFDGPNTLAPTGLFLGGEKYMVIQGEPGAVIRGKKGPGGVCIKKTTQALIFGIYDEPVAPGQCNMVVERLGDYLIEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
What are the official names of this protein?
Profilin Sal k 4.0201, Allergen Sal k 4.02.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NADD_STAA8
Sequence: MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHHDFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: CDPK4_ORYSJ
Sequence: MGACFSSHTATAAADGGSGKRQQRKGDHKGKLPDGGGGEKEKEAARVEFGYERDFEGRYQVGRLLGHGQFGYTFAATDRASGDRVAVKRIDKAKMVRPVAVEDVKREVKILKELKGHENIVHFYNAFEDDSYVYIVMELCEGGELLDRILAKKNSRYSEKDAAVVVRQMLKVAAECHLHGLVHRDMKPENFLFKSTKEDSPLKATDFGLSDFIKPGKKFHDIVGSAYYVAPEVLKRRSGPESDVWSIGVITYILLCGRRPFWNKTEDGIFREVLRNKPDFRKKPWPGISSGAKDFVKKLLVKNPRARLTAAQALSHPWVREGGEASEIPVDISVLSNMRQFVKYSRFKQFALRALASTLKEEELADLKDQFDAIDVDKSGSISIEEMRHALAKDLPWRLKGPRVLEIIQAIDSNTDGLVDFEEFVAATLHIHQMAELDSERWGLRCQAAFSKFDLDGDGYITPDELRMVQHTGLKGSIEPLLEEADIDKDGRISLSEFRKLLRTASMSNLPSPRGPPNPQPL
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger.
What are the official names of this protein?
Calcium-dependent protein kinase 4, OsCDPK4, OsCPK4, Calcium-dependent protein kinase OsCDPK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: GNB5_HUMAN
Sequence: MCDQTFLVNVFGSCDKCFKQRALRPVFKKSQQLSYCSTCAEIMATEGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA
What is the function of this protein?
Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable).  Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (PubMed:27677260).  May play an important role in neuronal signaling, including in the parasympathetic, but not sympathetic, control of heart rate (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-5, Gbeta5, Transducin beta chain 5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
What are the subcellular locations of this protein?
Membrane.
Protein: CTRA_GADMO
Sequence: MGHEVDSVLPGLFRRTYGCGRPAISPVITGYSRIVNGEEAVPHSWSWQVSLQDQTGFHFCGGSLINENWVVTAAHCNVKNYHRVVLGEHDRSSNSEGVQVMTVGQVFKHPRYNGFTINNDILLVKLATPATLNMRVSPVCLAETDDVFEGGMKCVTSGWGLTRYNAADTPALLQQAALPLLTNEQCKKFWGNKISDLMICAGAAGASSCMGDSGGPLVCQKAGSWTLVGIVSWGSGTCTPTMPGVYARVTELRAWVDQTIAAN
What are the official names of this protein?
Chymotrypsin A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: COQ7_BURMS
Sequence: MVFDELITEFDRGLRSIAGVSRMSRPVPKPAAAAPAELSAAERKHAAGLMRVNHVGEVCAQALYQAQKLTTSSAGLKEMFEHAAREEEDHLAWTAHRLKDLDSRPSLLNPLWYAGALAIGVVAGRLGDKVSLGFMAETERQVESHLDGHLSELPAADAESRAIVEQMRADEVKHGKSATDAGGIELPMPARMLMRAASKVMTSTAYYL
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYRR_COREF
Sequence: MSERRNTVVELLGENDVSRTVARIAHQIIEKTALDSEGADRVMLLGIPSGGVPLAERLAAKIEEFSGVRVDTGAIDITLYRDDLRNKPHRALQPTSIPSGGIDKTTVVLVDDVLFSGRTVRAALDALRDLGRPNYIQLAVLVDRGHRQLPIRADYVGKNLPTARAEDVTVMLREIDGRDAVTLTREEGEGDN
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: YO364_YEAST
Sequence: MVLQPFKFQNQKKFCRKANPTGRISHDFIYSHIQIFTVRILFTKVNLIDLRLLNTVAFKNGFLHFVQFRDRFVNRIIIHFTLQKGSSLIINRFVSCIRVFVVYCHRKAYQYENEEIQRKRCI
What are the official names of this protein?
Putative uncharacterized protein YOR364W.
Protein: NUOB_BORA1
Sequence: MAIDGILKQGFITTSADKFINWAKTGSMWPMTFGLACCAVEMMHAGAARYDLDQFGIIFRPSPRQSDLMIVAGTLCNKMGPALRKVYDQMPEPRWVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGLLQMQNKIRLTNTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.