PharMolix/UniProtQA huggingface dataset:
Protein: Y1282_METJA
Sequence: MRKIILIFFIFLILQNIYAYEKIYDVNHVCYYTLTSVELQKFVKTAEIITPLNADNKTTITKDTILVGNPEENPLTKKYIGFFKIKINKTFPGKNKGIIEKQIINGHTVILLAGSDIQGTYASIITFANLNDIPENPIICETSNKVNIYSTSLNSEYFRDFIEKNILTPKEIEKVKSLSYKLKGKDKKATIENIAKWVANNIKYDYDKCKKIESGKFSWDEYNTPSETVKTKKGVCLDYATLTSALLLNDNIIPYMLDVALYNTSSLKISSYHASVAVKIDNTYFVIDQQPYLIPINEYTAQTFEDNLRIASIVMFRVVKERDGIKLIKEKEVPGIAIYGDLINLLEMRFNN
What are the official names of this protein?
UPF0252 protein MJ1282.
What is the protein family that this protein belongs to?
Belongs to the UPF0252 family.
Protein: IFNAB_MOUSE
Sequence: MARLCAFLMILIVMSYWSTCSLGCDLPHTYNLRNKRALKVLAQMRRLTPLSCLKDRKDFGFPLEKVDAQQIQKAQSIPVLRDLTQQILNLFASKDSSAAWNATLLDSFCNDLHQQLNDLQGCLMQQVGVQESPLTQEDSLLAVRIYFHRITVFLREKKHSPCAWEVVRAEVWRALSSSANVLGRLREEKA
What is the function of this protein?
Has antiviral and antiproliferative activities (PubMed:15254193).  Produced by macrophages and stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase (By similarity).  During viral infection, mediates antiviral effect, either directly by inducing interferon-stimulated genes, either indirectly through stimulation of natural killer cells enabling them to control viral replication (PubMed:22912583).
What are the official names of this protein?
Interferon alpha-11, IFN-alpha-11, Limitin.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: CBS_MACFA
Sequence: MPSETPQAEVGPTGCPHLSGPHSAQGSLEKGLPGDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTVPEKSPKILPDILKKIGDTPMIRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGTLKPGDTIIEPTSGNTGIGLALTAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILRQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTMAVAVKAAQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLMEKKPWWWHLRVQELSLSAPLTVLPTVSCEHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYTQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFVAAQERDQK
What is the function of this protein?
Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine.  This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity).  Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).
What are the official names of this protein?
Cystathionine beta-synthase, Beta-thionase, Serine sulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS3_IDILO
Sequence: MGQKVHPNGIRLGISRPWNATWYANTNEFADNLHSDFQVRKFLNKELRNASVSRIVIDRPAKSVRVTIHTARPGVVIGKKGEDVEKLRKQVSKLTGAPAQINISEVRKPELDSQLVADNIAGQLERRVMFRRAMKRAVQNAIRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYSTSEANTTYGIIGVKVWIFRGEVLGGLPTEEKPAPKRGKNRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GCSP_CERS1
Sequence: MSFTPTDYNAYDFANRRHIGPSPSEMEEMLRVVGVSSLDQLIEETVPASIRQETPLDWAPLAEHELLARMREVAGKNRVMTSLIGQGYYGTVTPPAIQRNILENPAWYTAYTPYQPEIAQGRLEALLNYQTMVADLTGLPVANASLLDEATAAAEAMTMAERASKSKARAFFVDADCHPQTISVIRTRAEPLGIEVIVGHPAQLVPEDVFGALFQYPGTYGLVRDFTRDIAALHEAKALAVVATDLLALCLLKEPGAMGADIAIGSSQRFGVPMGYGGPHAAFMSCKDDLKRSMPGRLVGVSVDARGNKAYRLALQTREQHIRREKATSNVCTAQALLAVMASFYAVFHGPRGLRAIAERVHLNTVRLATALKEAGARVSPEAFFDTITVEVGVGQAGILAAARHRGINLRKVGRDRVGISLDETTDAGVIARVLDAFGIHEPAPAKVGLGFPEPLLRETGYLSHPVFQMNRAESEMMRYMRRLSDRDLALDRAMIPLGSCTMKLNAAAEMMPITWPEFGTLHPFAPADQAAGYHEAIGDLAQRLCRITGYDAMSMQPNSGAQGEYAGLLTILAYHRARGEAERTICLIPVSAHGTNPASAQMAGMKVVVVKSAPNGDVDLEDFRDKAAAAGDRLAACMITYPSTHGVFEETVREVCRITHEHGGQVYIDGANMNAMVGLVQPGAIGGDVSHLNLHKTFAIPHGGGGPGMGPIGVKAHLAPYLPGHPEVTGPLTGGHDEAADEGPVSAAPYGSASILLISWAYCLMMGGEGLTQATRVAILNANYIAARLRGAYKVLFMGNRGRVAHECILDTRPFAEAGVTVDDIAKRLIDNGFHAPTMSWPVPGTLMVEPTESETKAEIDRFVAALLAIREEIRAVEEGEIAAGDSPLRHAPHTVEDLVADWDRKYPREQGCFPPGSFRVDKYWPPVGRVDNAWGDRNLVCTCPPVESYSIAAQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: RLMN_DESHY
Sequence: MNTMKRMDCRDLNQSELTQHCAELGLPKFRGRQVFQWVQQKAVQNWEELKNIGAGDRQKLQDGLFLQPLRKVREQISQDGTRKFLFRCADGETLECVLMDYDRRKNRDRHTVCVSTQIGCAVGCAFCATGLGGWRRNLSPGEILGQVLDITYLMRQEDPDFQVTNIVFMGMGEPLLNYEAVLKAIELLNDPEGQGIGMRRMTISTSGVAPKIRQLAKDNPQVGLAVSLHSAHNTTRDQLIPMNRKYPLEELMEACRDYTTLTNRRITFEIALISGQATLEAAQAVGHLLKRQLAHVNLIPVNPVAGTGMARPTAKEVQQFAQCLESMGIPVSVREEKGTDIDAACGQLRRQLECEQK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_FINM2
Sequence: MNKYELVLIFKPELSEEDRNTVFSRIQQVIDENGKLEEVHDWGKRKLAYEINYIKEGYYYIVNFDLDPQFVKEIERRCRLFDQIIRYMVVRVDEQ
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: CTU1_DEBHA
Sequence: MPEEKVATKKIKLSALCELCNGRKAVMKRPKNLQKLCKECFYNVFETEIHNTIADANLFQPGDKVAIGASGGKDSTVLASVLKTLNERYDYRLELVLLSIDEGIKGYRDDSLATVKRNQAQYNMALEIISYKDLYNWSMDEIVSCAGIRSSCTYCGVLRRQALDRGAAKLGINHVVTGHNADDMAETVLMNLLRGDTARLEKSCTILTQSTGSPIKRSKPFKYSYQKEIVLYAHYKKLDYFSTECSYAPEAFRGTARELLKSLEAIRPSCIMDIIYSGEHLALAPKKKRTQQYKNKKKTQVDNEHEINADGSITIGTREFKDGNRCENCGYLTSNKICKACVLLAGLEMNRAKVSVDNNTAVDGAAKLTKTLEQLSF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKQP_SCHPO
Sequence: MSCLNLHVPKNPVGKYIPLVVLLQMYIIYVEPYYGLHYFESVRQFLGPKILYGTVYFLVICHSIESAIAFLLCLKKGLPFCSSMKWIVSTFIFGGPTLAMLNKQKKHIA
What are the official names of this protein?
Uncharacterized membrane protein C688.16.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LEU3_DEHM1
Sequence: MDFKLTVLPGDGIGPEVMAEGLKVLNAVAKKYKHSFEYQYGLIGGCCIDKEGVALSPETLAMCKKSDAVLLAAVGDPRFDDPKLPVHPEDGLLALRRGLGLFANIRPVKVAPSLVNSAPIKAEIVKGTDFIFIRELTGGVYFAKPKKRWTTPSGIRKATDSMTYSEKEIERIVRVGFELARSRKKKLVSVDKANVLLSSRLWRQIVIEIAKDYPDITVEHILVDACAMKLILAPTYFDVIVTENMFGDILTDEASMLAGSMGMLPSASLAGIPAKGTKTFGLYEPIHGSAPTIAKQNIANPIATILSIAMMLRYSCGLETEAAEIEAAVDKVLAAGYATIDIFKEGNTKLGTAEMGSQIAKIIGG
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCB23_ARATH
Sequence: MVRSDENSLGLIGSMSLQGGGVVGKIKTTATTGPTRRALSTINKNITEAPSYPYAVNKRSVSERDGICNKPPVHRPVTRKFAAQLADHKPHIRDEETKKPDSVSSEEPETIIIDVDESDKEGGDSNEPMFVQHTEAMLEEIEQMEKEIEMEDADKEEEPVIDIDACDKNNPLAAVEYIHDMHTFYKNFEKLSCVPPNYMDNQQDLNERMRGILIDWLIEVHYKFELMEETLYLTINVIDRFLAVHQIVRKKLQLVGVTALLLACKYEEVSVPVVDDLILISDKAYSRREVLDMEKLMANTLQFNFSLPTPYVFMKRFLKAAQSDKKLEILSFFMIELCLVEYEMLEYLPSKLAASAIYTAQCTLKGFEEWSKTCEFHTGYNEKQLLACARKMVAFHHKAGTGKLTGVHRKYNTSKFCHAARTEPAGFLI
What are the official names of this protein?
Cyclin-B2-3, G2/mitotic-specific cyclin-B2-3, CycB2;3.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: CWC2_LEPMC
Sequence: MTEVQPPPAQSTVATADTPSLAPDTTLETSTSTELAPITTEQTIITTNAEGKKVKKIIRRKRRPARPQVDPATFKTDTPAPTGTSFNIWYNKWSGGDREDKYLSQTAAQGRCNVARDSGYTKADKTPGSYFCLFFARGICPKGVDCEYLHRLPTVTDIFPSNIDCFGRDKHSDYRDDMGGVGSFQRQNRTLYIGRIHVTDDIEEIVARHFQEWGQIERTRVLTARGVAFVTYMNEANSQFAKEAMAHQSLDHNEILNVRWATVDPNPQAAKREAHRIEEQAAEAIRKALPAAYVAELEGRDPEAKKRRKIEGSFGLQGYEAPDDVWYAKEKAEWEAAKEIEAAGGAAXPRQMIESGEDAHAHEADCAAMQVAPSGQHSQGNGIFSTSTLAALRGYTAAPAKPKVAPVAGPLVGYGSDDDSD
What is the function of this protein?
Involved in the first step of pre-mRNA splicing.  Required for cell growth and cell cycle control.  Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex.  May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA.  Associates predominantly with U6 snRNAs in assembled active spliceosomes.  Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor CWC2.
What is the protein family that this protein belongs to?
Belongs to the RRM CWC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPOLM_MOUSE
Sequence: MLPKRRRVRAGSPHSAVASSTPPSVVRFPDVAIYLAEPRMGRSRRAFLTRLARSKGFRVLDAYSSKVTHVVMEGTSAKEAICWQKNMDALPTGCPQPALLDISWFTESMAAGQPVPEEGRHHLEVAEPRKEPPVSASMPAYACQRPSPLTHHNTLLSEALETLAEAAGFEANEGRLLSFSRAASVLKSLPCPVASLSQLHGLPYFGEHSTRVIQELLEHGTCEEVKQVRCSERYQTMKLFTQVFGVGVKTANRWYQEGLRTLDELREQPQRLTQQQKAGLQYYQDLSTPVRRADAEALQQLIEAAVRQTLPGATVTLTGGFRRGKLQGHDVDFLITHPEEGQEVGLLPKVMSCLQSQGLVLYHQYHRSHLADSAHNLRQRSSTMDAFERSFCILGLPQPQQAALAGALPPCPTWKAVRVDLVVTPSSQFPFALLGWTGSQFFERELRRFSRQEKGLWLNSHGLFDPEQKRVFHATSEEDVFRLLGLKYLPPEQRNA
What is the function of this protein?
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).  Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
What are the official names of this protein?
DNA-directed DNA/RNA polymerase mu, Pol Mu, Terminal transferase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OMPA_SHIFL
Sequence: MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIPNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDANTIGTRPDNGLLSLGVSYRFGQGEAAPVVAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
What is the function of this protein?
(Microbial infection) Serves as a secondary receptor during phage Sf6 infection; infection requires both lipopolysaccharide (LPS) and the OmpA beta-barrel.
What are the official names of this protein?
Outer membrane protein A, Outer membrane porin A.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
What are the subcellular locations of this protein?
Extracellular vesicle. Note=(Microbial infection) Upon infection with phage Sf6 is found in extracellular vesicles that associate with the tails of mature phage particles. SUBCELLULAR LOCATION: Cell outer membrane; Multi- pass membrane protein.
Protein: END8_ECOLC
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKTYQSQLIGQHVTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTILLYSASDIEMLRPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLEIPRFSYATRGQVDENKHHGALFRFKVFHRDGEPCERCGSIIEKTTLSSRPFYWCPGCQH
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: ECDB_ASPRU
Sequence: MVKMRKRLAVACDACRSRRVKCDGQRPSCMGCLSRGLDCSYQRLPEPPATRLETELANVNMRLDYLAMLLSRQSQPQAPPPVLLASARPSSNPLSSHEDSPFRLLATDSIMSVLGLEDHFARRLVQLERASLLASTTTLSRMFFISHQQVTDALIAFSERVHTFYPILPLDFSERYFATLSGPLAPSCQTCLALLVAAIGCIARDPTMGDEYFEAALASLPTVLAECTLASIQCLVFLSIYYCCRLKPCQAHDYCLIASFKIQNLFKSELSVQLDVATSDTWKLDEYIPLPNCRYTWQFSCPPLPGNLAGVSPESASSSSSSISIDSTNSSTSTASDQAQSFFLAEIAMRRMLHRCNSAVAQSSDGRFCYAPSIALELERQLEEWYDYLPASIRFVREPAGGSFNGDQSALSPLSTFLNVQYCCCKLSIYWPAVYQVIQDDKATPQLLEHCQRFIDSYVQLLPRIALAIDKCLIYKWTLSVTFFVTTMAALKVANTAALRAAQHERLHESLALAGTVGWKNTEDSPSLELLRLNLSQHLREAKQK
What are the official names of this protein?
Putative transcription factor ecdB.
What are the subcellular locations of this protein?
Nucleus.
Protein: RF1_FRATN
Sequence: MKDSIKAKLQSLIERHEEVSALLSEAGIISDQNKFRDLSKEYSHLEPIVKAFKEYTQALEDKQAAYEMLNEKDAELVEMAKEELKLANEAIEKLESELQILLLPRDPNDDANVFLEIRAGTGGDEASIFSGDLFKMYSKYAEQRGWKIEVISASEGEHGGYKEIISRIYGDGVYSQLKFESGAHRVQRVPATESQGRIHTSACTVAVMPEADEVEGIDINPADIKVDTFRASGAGGQHVNKTDSAIRITHIPTGVVVECQDQRSQHKNRAAAMLMLKSKLLQAEIDKQQKEQSDTRKSLVGSGDRSERIRTYNYPQGRVTDHRINLTLYKLDEVMEGSLDSIIQPLVLEHQADLLATMSDE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_SHEPW
Sequence: MNQLRLEPIEKVNGTINIPGSKSISNRALLLATLAEGTTTLTNLLDSDDIRYMLASLKQLGVNYRLTNNNTVCEVDGIAGVLNADTAQTLFLGNAGTAMRPLCAALTLGQGEFTLTGEPRMEERPIGDLVDSLRQLGADVSYLKNDGFPPLTINATGLSGGDVEIAGDLSSQFLTALLMVAPLAKGDVNIKIKGELVSKPYIDITLALMAQFGVNVTNNNYVSFEIKTGQRYISPGKLLVEGDASSASYFLAAGAIKGGEVKVTGVGKLSIQGDVKFADVLAQMGADIEWGDDYIIARGSKLNAVDLDMNHIPDAAMTIATAALFATGTTHIRNIYNWRIKETDRLAAMATELRKVGAIVDEGHDYISVTPPVKPHTANIDTYNDHRMAMCFSMLAFADCGITINEPECTSKTFPDYFTQFNALAN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_LIMRD
Sequence: MRIDILSLFPNMFQATMGESIIGKAQDNGFIDINVTDFRQYTTDKHNHVDDAPFGGGAGMLLQAQPIFDAMDAIHEQTKDQYSKGRVILMDPAGRKFDQAYAKELAQEDHLTFICGHYEGYDERIRNLVTDEASLGDYVLTGGELAAMVMIDATVRFVPGVLGNMSSPMGDSFSNGLLEYPQYTRPADFRGMKVPEVLTSGNHQKIKEWRMRESLRRTLHRRPDLLKTAKLSREQQLMLEDIKLDEDPTVPD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MADD_MOUSE
Sequence: MVQKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHPEFPLPPDVVFFCQPEGCLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRMPKEKVEGGAGPRGKEGAHTSGASEEAATGSSESGSTLQPPSADSTPDINQSPWGKRRAKAGSRSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSALLQDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQQALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPESLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAEKLARTQAVEYFGEWILNPSNYAFQRIHNNTFDPALIGDKPKWYAHQLQPIHYRVYDGNSQLAEALSVPPERDSDSDPTEDSGSDSQDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPLTHAALGDASEVEIDELQPQKEGEEPGPDSENSQENPPLRSSSSTTASSSPSTVVHSAHSEAADSTEMGDKATAGISKPLPPVPPSICKSTVDRRQTETGEGSVCQRTYDNPYFEPQYGFPPEEDEEEQGESYTPRFSQHVSGSRAQKLLRPNSLKLASDSDAESDSRASSPNSTVSNNSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKTTPFPSLKVFGLNTLMEIVTEAGPGSGEGNRRALVDQKSSVIKHSPTVKREPSSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVLSKLNRAVQSEDDARQDVIQDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTENVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFVASVELWNKHQEVKKQKALEKQRPEGIKPVFDLGETEEKKSQMSADSGVSLTSASQRTDQDSVIGVSPAVMIRSSSQDSEVSTVSNSSGETLGADSDLSSNAGDGPGGEGSAHLASSRATLSDSEIETNSATSAIFGKAHSLKPKEKPAGSPIRSSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSLSKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQVNEVLDQLNSLNGRDLSIRSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDMKTGEGGLLQVTLEGINLKFMHNQFLKLKKW
What is the function of this protein?
Guanyl-nucleotide exchange factor that regulates small GTPases of the Rab family (PubMed:18559336, PubMed:11359932).  Converts GDP-bound inactive form of RAB27A and RAB27B to the GTP-bound active forms (PubMed:18559336).  Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms, GTPases involved in synaptic vesicle exocytosis and vesicle secretion (By similarity).  Plays a role in synaptic vesicle formation and in vesicle trafficking at the neuromuscular junction (PubMed:11359932, PubMed:12388783, PubMed:18849981).  Involved in up-regulating a post-docking step of synaptic exocytosis in central synapses (PubMed:12388783).  Probably by binding to the motor proteins KIF1B and KIF1A, mediates motor-dependent transport of GTP-RAB3A-positive vesicles to the presynaptic nerve terminals (PubMed:18849981).  Plays a role in TNFA-mediated activation of the MAPK pathway, including ERK1/2 (By similarity).  May link TNFRSF1A with MAP kinase activation (By similarity).  May be involved in the regulation of TNFA-induced apoptosis (By similarity).
What are the official names of this protein?
MAP kinase-activating death domain protein, Rab3 GDP/GTP exchange factor, RabGEF, Rab3 GDP/GTP exchange protein, Rab3GEP.
What is the protein family that this protein belongs to?
Belongs to the MADD family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Cell projection, axon.
Protein: NDK_GRABC
Sequence: MAIERTFSIIKPDATRRNLTGRINAVFEENGLRIVAQKRVQLSQAQAEAFYGVHRERPFFNDLVSFMISGPVVVQVLEGENAVARNRELMGATDPKKADAGTIRAQFAESIEANSVHGSDSAENAAIEIAYFFAGSEIVA
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAMP2_HUMAN
Sequence: MSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane (By similarity).  Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters.  Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles (By similarity) (PubMed:30929742).  Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.
What are the official names of this protein?
Vesicle-associated membrane protein 2, VAMP-2, Synaptobrevin-2.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
Protein: RL25_MYCPA
Sequence: MAKQALNQLTAAVRTETGKGASRRARRAGKIPAVLYGHGTDPQHLELPGHDFAAVLRHAGTNAVLTLDIDGKEQLALTKALDIHPIRRTIQHADLLVVRRGEKVVVEVTVVIEGDAAPGSLVTQEASTIEIEAEALSIPEQFTVSVEDAEPGTQFTAGQIALPKGVNLISDPELLVVNVVNAPTAEELAEEGAGEVTEEPAAAEAEEAGEEEAAEAESE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.