PharMolix/UniProtQA huggingface dataset:
Protein: MINP1_MOUSE
Sequence: MLRGARSHLPASVAPAAVLAAALLSSFARCSLPGRGDPVASVLSPYFGTKTRYEDANPWLLVDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRKLKQLQGLLQTRESRDGGSQVAAALAEWPLWYGDWMDGQLVEKGRQDMRQLALRLAALFPDLFSRENYDRLRLITSSKHRCVDSSAAFLQGLWQHYHPGLPPPDVSDMECGPPRINDKLMRFFDHCEKFLTDVERNETALYHVEAFKTGPEMQKVLKKVAATLQVPMNSLNADLIQVAFFTCSFDLAIKGVHSPWCDVFDVDDARVLEYLNDLKQYWKRSYGYTINSRSSCNLFQDIFLHLDKAVEQKQRSQPVSSPVILQFGHAETLLPLLSLMGYFKDKEPLTAYNFEEQVNRKFRSGHIVPYASNLIFVLYHCDNAQSPEEQFQIQLLLNEKVLPLAHSQRPVGLYEELKTHYRDILQSCQTSKECSPPKANITSDEL
What is the function of this protein?
Acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate (By similarity).  Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6).  May play a role in bone development (endochondral ossification).  May play a role in the transition of chondrocytes from proliferation to hypertrophy (By similarity).  Through the regulation of intracellular inositol polyphosphates, may control intracellular cation homeostasis, including that of calcium and iron, hence affecting free cation availability required for neural cell signaling (PubMed:33257696).
What are the official names of this protein?
Multiple inositol polyphosphate phosphatase 1, 2,3-bisphosphoglycerate 3-phosphatase, 2,3-BPG phosphatase, Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase, Ins(1,3,4,5)P(4) 3-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family. MINPP1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Cell membrane. Note=Also attached to the plasma membrane in erythrocytes.
Protein: KAD_CLOB6
Sequence: MRVILLGPPGAGKGTQAKLISEKFSIPHISTGDIFRANIKEKTPLGIEAKRYIDNGQLVPDEVTIGIVKDRLTKDDCDNGFLLDGFPRTVAQAEALDEFLKGINKELDVALLIKVPEEFILERMTGRRVCTSCGASYHIRFNPPKIEGKCDICDNELIQRKDDTEATVKERLEVYSKQTYPLINYYKDNGIISEVNGTESIDEVFGNISNILGRDK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS8_CAMSI
Sequence: MASSQVGDMVNGNAEPTRHLAKFPPSLWGDRFTSFTLDKQLWDKYGNEIEVLKEQVRSMVVAGGRKAAEQINLINVLERLGVSYHFEKEIEEQLEQLFAKFEDNEDYDLFTIALHFRIFRQHGYKMSCDVFNKFRDSNGEFKETVSNDVQGMLSLYEATYLKIRGEGFLDEAHAFTIAQLESLVGGPHLSSDLSEQVMHALKQSIHRGFPRLEAKHFISFYEKDASRNETLLRLAKLDFNQLQLSHREELCHIFRWWKELDLISKVPYARDRAVECFFWSTCAYYEPQHSVGRAVLTKIMLLLSVTDDTYDAYGTYDELKLYTNAVQRWDVSAMDELPDYMKALYRALLNVYDEVERDLAKQGRDYGVHHSKEAFKEIVRSYEIEAEWFKEGYVASFEEYMKNALVTSTGRLHTTSCFMGLEADVATTEAFEWILTKPKMVAASGAIGRLVDDVMSHDEEQERGHVATGLDCYMKQHGVSKQEAIVELYKMIENAWRDINEEMLKPTAISMKLLIRVLNLSRISDVVYKYVDGYTHPEIIKDHVISLFEDPIPM
What is the function of this protein?
Terpene synthase that catalyzes the biosynthesis of the terpene valerianol.
What are the official names of this protein?
Valerianol synthase TPS8, Terpene synthase 8, CsiTPS8.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: MPTN_METMA
Sequence: MKKIGIAITDPEDWTARALIKAAKEKGFSPLVFDLSDAEVRIGSGISEPASIFKAGEVLLSDLDALIVRDVGAGAFEGVSFRFDILRELEAEGVSVINSPEAIQNAANKYHASYLLAKAGLPVPETVAVQSLEAALKVISEFGDAVIKPVFGYKGKDIARVKNREIRFSDRKIEPAPVEEILEKLLEEKGMLYIQEFIENPGRDIRAFVVGGTAIGAIYRKAAAGSWVNNLSQGGSSDRCVLTDEQEKIAEKASLALGTTFAGIDIIEGTEESEENKKTEGMSSENRKSPRILEVNGTPSGKGIFDAWGINPADHILEYLKNIL
What is the function of this protein?
Catalyzes the ATP or GTP-dependent addition of one L-glutamate molecule to tetrahydromethanopterin, producing tetrahydrosarcinapterin.
What are the official names of this protein?
Tetrahydromethanopterin:alpha-L-glutamate ligase, H(4)MPT:alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family. MptN subfamily.
Protein: DDN1_BOVIN
Sequence: MVLLLLLVALLSPTGEAGKIIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPGMMCSVAGWGRLGVNMPSTDNLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKNSFSGDSGGPLVCNGVAQGIVSYGRNDGTTPDVYTRISSFLSWIHSTMRRYKRQGSV
What is the function of this protein?
Protease which has both trypsin-like and chymotrypsin-like activities.  Shows a preferential cleavage after Lys, Arg, Tyr, Phe, and Leu residues.
What are the official names of this protein?
Duodenase-1, Duodenase I, Duodenum serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: ZAPB_SALPA
Sequence: MSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLTQEVQSAQHQREELERENNSLKEQQSGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: MUG51_SCHPO
Sequence: MPALLKINKKKNGQTKIDRLFSKRRKTSLAIEKNHSKASMCTGQSPLNIISYNVPPLIVLRNKTIRNSIEVLVEEMFRDIQMRQQTNVLVAQCPRMIVETQLIGLFQSNYTSVAEELEQSIRTGDIRRLYLNRSDKFCGESCLILRPEFDKLFTYYLCKFKDQEHIYTLIFKLHKLLIENPLPSYTSEELKFNWEERRLLISMGFLILAGTDSYGISLPNLGIFTHILRNSRNDLSNYLKKRPYREVIESSLYNRNVSVACKKKNEAFFGWKFRLCDAIGAGLVDSFMTTCGRAFRLTKKGLEMKF
What is the function of this protein?
Serine/threonine-protein kinase (By similarity).  Has a role in meiosis (PubMed:16303567).
What are the official names of this protein?
Serine/threonine-protein kinase mug51, Meiotically up-regulated gene 51 protein.
What is the protein family that this protein belongs to?
Belongs to the STK19 family.
Protein: ATPD_JANSC
Sequence: MSEPASISTGIAARYATAMFELAEEAKALPALEKDVDALDAALSESADLRDLIHSPIYGRDEASAAIGGVADAMKLQDMTGNTLRLMASKRRLFVLPALLSELRERIADHKGEVTAEVTSAKALTKTQLDKLTKSLKAQVGKTVTVKETVDENIIGGLIVKIGSKMIDTSVRSKLNALQNTMKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NRDR_ACIB3
Sequence: MHCPFCNAADSKVIDSRLAAEGCQIRRRRECVSCGERFTTFESYEVVMPRVIKSNGKNEPFDEAKLRRSLMHALQKRPVTQEQIETVLSDIQLQIRRLGERDVKSRTIGEIVMQSLFALDHVAYVRFASVYQDFQDVEAFRRQIEQMQQREH
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MNMG_LEGPC
Sequence: MNLEQLYDVIVVGGGHAGTEAALAAARLGVKTLLLTHNIDLLGQMSCNPAIGGIGKGHLVKEIDALDGAMAKAADQAGIQFRILNASKGPAVRATRAQADRVLYRKAIRTQLQSQANLTIFQQAVDDLKIEGGLVTGVVTQMGLTLKARAVVLTVGTFLGGKIHVGMNQYAGGRAGDPPSIALSKSLRDLDLPVGRLKTGTPPRIDRRTIDFSQMVEQPGDTPVPVFSYLGTASDHPQQVPCHITHTTEATHDIIRNNLDKSPMYAGVIEGVGPRYCPSIEDKIVRFADKTSHQIFVEPEGLTTEEIYPNGISTSLPFEVQVQFVRTIKGFENAHITRPGYAIEYDYFDPRGLTSFLQTKAIPNLFFAGQINGTTGYEEAAAQGIIAGMNAALQIKDQELWCPRRDEAYIGVLIDDLITCGTQEPYRMFTSRAEYRLLLREDNADLRLTEKGRQLGLVGDERWDSFSKKREAIESTQALLHNSWVRVHHNDLFKEALLNPMQHDCRAAEFLKRPEINYQHLLMMDDLNLPELPQEITEQIEIQNKYAGYIDRQQQEIEKLRKHENTMLPETLDYNDVVGLSSEVIQKLNRIKPTSLAQAGRISGVTPAALSLLLVHLKKSRLPV
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_STRGC
Sequence: MAQMTVQIVTPDGLVYDHHAAFVSVKTIDGELGILPRHINTIAVLEVDQVKVRRVDDDKHIDWVAVNGGIIEIADNVITIVADSAERERDIDISRAERAKLRAEQEIEEAHDKHLIDQERRAKIALQRAINRINVGSK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YEJL_ECOSM
Sequence: MPQISRYSDEQVEQLLAELLNILEKHKAPTDLSLMVLGNMVTNLINTSIAPAQRQAIANSFARALQSSINEDKAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: ALLC_PSE14
Sequence: MKVYAAPFEKFVNLADARLGTKILSVTDDWFADANRLFQPTPAVWKEGVFDDNGKWMDGWESRRKRFEGYDSAVIRLGVAGTIKGVDIDTSFFTGNFPPSASLEACFLASGEPDENTAWTEVLPSVELQGNSHHYHEITNDQAFSHLRFNIYPDGGVARLRVYGVPHRDWSKVSEDEQIDLVAALNGGRSIACSDEHYGSMSNILNPGRGVNMGDGWETARRRTPGNDWVIVALGHKGEVEKVIVDTLHFKGNYPDSCSIQGAFVKGGTDSQIETQSLFWRELLPSQKLTMHAEHEFAEQINAIGPITHIRLNVFPDGGVSRLRVLGKVSR
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: SYC_BACAN
Sequence: MTIHIYNTLTRQKEEFTPLEENKVKMYVCGPTVYNYIHIGNARPPMVFDTVRRYLEYKGYDVQYVSNFTDVDDKLIKAANELGEDVPTIADRFVEAYFEDVTALGCKHATVHPRVTENMDIIIEFIQELVNKGYAYESEGDVYFRTKEFEGYGKLSHQPIADLRHGARIEVGEKKQDPLDFALWKAAKEGEIFWESPWGQGRPGWHIECSAMARKYLGDTIDIHAGGQDLAFPHHENEIAQSEALTGKTFARYWMHNGYININNEKMSKSLGNFILVHDIIKQYDPQLIRFFMLSVHYRHPINFSEELLQSTNNGLERIKTAYGNLKHRMESSTDLTDHNEKWLADLEKFQTAFEEAMNDDFNTANAITELYNVANHANQYLLEEHTSTVVIEAYVKQLETLFDILGLELAQEELLDEEIEALIQKRIEARKNRDFALSDQIRDDLKDRNIILEDTAQGTRWKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_LEGPL
Sequence: MLVLGIESSCDETGVAVYDSESGLLSHALHSQIATHRVHGGVVPELASRDHVNYLVPLVDEVLTKAKIRKNQLDGIAYTAGPGLIGALLVGSCFAKSLAYALNIPALAIHHLEAHLLAAKMETPSLDFPFIALLVSGGHCQLIEVNNIGEYRLLGDTLDDAVGEAFDKTAKLMGIPYPGGAVLANLADQCLSTPYQFPRPMTDRPGLDFSFSGLKTHALNTWNQSAKKQGDRSEIAKAFQQAVVETLIIKCKRAIKESQSKRLVVAGGVGANKALRSALQKWINDIKGEVYFPALEYCTDNGAMVAYAGCLRMMRGESDGGLGVMVKPRWPLA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JAL46_ARATH
Sequence: MTERSEALGKDGNRRWDDKSDHDDVTKIYVNYSLMGIESIRFDYVKSGKPIEGPFRGETYNTYTHTFEINHLKNEHLESVEGSYTQRGIQTLQFKTNLRISEPIGYPGKDGIKFILAVEGKKIIGFHGSTYFRLYSLGAYFTRVTPTRIEAIGGKVGTKWDDGVDQAGFTKIHVRSGQEGIQFIKFEYVDKNGRLRDGSIHGSIYRRGSPHVFEIRHVDKEYLVSVEGYYDGDGDCAVIQALRFRTNVKTSQLMGPKTGKKFRLAASGMKIVGFHGYAEKNLTSLGGYFTPIIPTKSECQGVTERSTLWDSGAFEGIRKVSVTWRSYCIRCFRINYENDGKVVKRAHGMNDDSRITDEFVVDYPYEVITSIVGTMNDSYVTSFVFKTSKGRTSRTFGERTSDSVEFVIESKGCAVVGFHGWYAPLGAGYITALGAHFYPMPLPPAAEKLEAQGGAGGVPWDDGSNFERVRKIYIGTCEVGIVSVRFLYENDIEEIVVGDHHGNKNLLRHEEFDLDNACEYLTSVEGSYDVIPGSEDVEVILMLKFTTNKRTSPCYGLDDDPTFVLHKAGHRIIGFHGKSSNMLHKLGIHVLPITDP
What are the official names of this protein?
Jacalin-related lectin 46.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: Y253_METJA
Sequence: MKKKDILIVGCGNLLFGDDGFGCEVVSKLEKMNLPDNVEVIDAGASGAYYLMTLVDEDIKKIIVVDAIDFDLEPGTIKKIDVDELPNIKKYSFDAHNVPLAPFLKDLHNKGIEVVVIGCQGKEFTMPDIKPGLSEEVAKAVDKAIEIILGEIKK
What are the official names of this protein?
Putative hydrogenase maturation protease MJ0253.
What is the protein family that this protein belongs to?
Belongs to the peptidase A31 family.
Protein: RRM4_USTMA
Sequence: MSDSIYAPHNKHKLEAARAADAAADDAATVSALVEPTDSTAQASHAAEQTIDAHQQAGDVEPERCHPHLTRPLLYLSGVDATMTDKELAGLVFDQVLPVRLKIDRTVGEGQTASGTVEFQTLDKAEKAYATVRPPIQLRINQDASIREPHPSAKPRLVKQLPPTSDDAFVYDLFRPFGPLRRAQCLLTNPAGIHTGFKGMAVLEFYSEQDAQRAESEMHCSEVGGKSISVAIDTATRKVSAAAAEFRPSAAAFVPAGSMSPSAPSFDPYPAGSRSVSTGSAASIYATSGAAPTHDTRNGAQKGARVPLQYSSQASTYVDPCNLFIKNLDPNMESNDLFDTFKRFGHIVSARVMRDDNGKSREFGFVSFTTPDEAQQALQAMDNAKLGTKKIIVRLHEPKTMRQEKLAARYNAANADNSDMSSNSPPTEARKADKRQSRSYFKAGVPSDASGLVDEEQLRSLSTVVRNELLSGEFTRRIPKVSSVTEAQLDDVVGELLSLKLADAVEALNNPISLIQRISDAREQLAQKSASTLTAPSPAPLSAEHPAMLGIQAQRSVSSASSTGEGGASVKERERLLKAVISVTESGAPVEDITDMIASLPKKDRALALFNPEFLKQKVDEAKDILDITDESGEDLSPPRASSGSAPVPLSVQTPASAIFKDASNGQSSISPGAAEAYTLSTLAALPAAEIVRLANSQSSSGLPLPKADPATVKATDDFIDSLQGKAAHDQKQKLGDQLFKKIRTFGVKGAPKLTIHLLDSEDLRALAHLMNSYEDVLKEKVQHKVAAGLNK
What is the function of this protein?
Key RNA-binding protein involved in the formation of polar-growing hyphae which is essential for infection by the plant pathogen (PubMed:15643068, PubMed:17105762, PubMed:19494833).  During filamentation, assembles into particles that shuttle bidirectionally along microtubules to both poles (PubMed:17105762, PubMed:19494833, PubMed:30738139).  The RRM4 transport particles are part of the endosomal mRNP transport that regulates polarity of the infectious hyphae by transporting distinct mRNAs encoding, for example, the ubiquitin fusion protein UBI1, the small G protein RHO3, or the septin CDC3, from the nucleus to cell poles (PubMed:17105762, PubMed:19494833, PubMed:22357951, PubMed:24355572, PubMed:25985087, PubMed:30738139).  Recognizes a broad spectrum of cargo mRNAs and precisely binds at stop codons, which constitute landmark sites of translation, suggesting an intimate connection of mRNA transport and translation (PubMed:30552148).  Binds also to the specific binding motif UAUG of cargo mRNAs via its third RRM (PubMed:30552148).  Plus-end-directed KIN3, a kinesin-3 type motor, mediates anterograde transport of RRM4-containing mRNPs whereas split dynein DYM1-DYN2 functions in retrograde movement of mRNPs (PubMed:22357951).
What are the official names of this protein?
RNA-binding protein RRM4.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Endosome. Note=Assembles into particles that shuttle along microtubules to both poles (PubMed:17105762, PubMed:19494833). Shuttles with RAB5A-positive endosomes along microtubules (PubMed:22357951, PubMed:25985087).
Protein: RS14Z_HELPH
Sequence: MAKKSMIAKAQRKPKFQVRAYTRCRICGRPHSVYRDFGLCRVCLRKMGSEGLIPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: PSBZ_EUCGG
Sequence: MTIAFQLAVFALIATSLILLISVPVVFASPDGWSSNKNVVFSGTSLWIGLVFLVGILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: 3SA5_NAJHA
Sequence: LKCHKLVPPFWKTCPEGKNLCYKMYMVATPMIPVKRGCIDVCPKNSALVKYMCCNTNKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 5, Toxin CM-6.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: JANM_PENJA
Sequence: MSKSEFQVIIVGGSIGGLTLAHCLRRAGIDHIILEKSSSPAPQIGASIGILPNGARILDQLQLWSEVEDYIEPLSTATIGLPDGFSFSSSYPQIINERFGFPIAFLDRQLLLEILYQRYPDRSKIRLEEKVTAVETSDSGATVTTSNGSVYRGGLVVGADGVHSIVRREIWRASKKLSSGLTAEFRCIFGISSAIKGLNVGEQVNALFDGLTIVTIHGKNGRVYWFVIQKLDKKYIYPNCPRYTKHDTTVAAEQLRNIQFYRDITFGQVWENRETASMTVLEENTFKTWHYGRLVLLGDSVHKMTPNIGQGANMAIEDAAALTNLLHNLQKISGTLSSTAAQIETILRQYRRIRYERVESIYRDSRFLVRFQARDGLLNILLSRYYAPYAGDLPADMASKTIADGVMCDFLPPPKRSGDGWKRYRRDGQLRGWRFHAMLCILMLAILYTWVGRTNLDSIVFSACGSLFQKLSVPT
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes janthitremanes such as shearinine K or shearinine A (PubMed:26213965).  The geranylgeranyl diphosphate (GGPP) synthase janG catalyzes the first step in janthitremane biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:26213965).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase janC then forms 3-geranylgeranylindole (3-GGI) (PubMed:26213965).  Epoxidation by the FAD-dependent monooxygenase janM leads to a epoxidized-GGI that is substrate of the terpene cyclase janB for cyclization to yield paspaline (PubMed:26213965).  Paspaline is subsequently converted to 13-desoxypaspaline by the cytochrome P450 monooxygenase janP, via beta-PC-M6 in a series of alpha-face oxidations (Probable).  The cytochrome P450 monooxygenase janQ is proposed to carry out sequential beta-face oxidation steps at C-7 and C-13 of 13-desoxypaspaline to form paspalicine and paspalinine respectively (Probable).  The indole diterpene prenyltransferase janD may then convert paspalinine into shearinine K which is substrate of janO and/or additional enzymes for oxidation and cyclization to generate shearinine A (Probable).
What are the official names of this protein?
FAD-dependent monooxygenase janM, Janthitremanes biosynthesis cluster protein M.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACXC_XANP2
Sequence: MAYTRSKIVDLVDGKIDPDTLHQMLSTPKDPERFVTYVEILQERMPWDDKIILPLGPKLFIVQQKVSKKWTVRCECGHDFCDWKDNWKLSARVHVRDTPQKMEEIYPRLMAPTPSWQVIREYFCPECGTLHDVEAPTPWYPVIHDFSPDIEGFYQEWLGLPVPERADA
What is the function of this protein?
Catalyzes the carboxylation of acetone to form acetoacetate.  Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.
What are the official names of this protein?
Acetone carboxylase gamma subunit.
Protein: SYH_BACLD
Sequence: MGFNIPRGTQDILPGESERWQYVEKIARETCHAYQYKEIRTPIFEHTELFSRGVGESTDIVQKEMYTFADKKGRSLTLRPEGTASAVRSFVENKLFANPVQPTKLYYIGPMFRYERPQTGRYRQFYQFGIEAIGSNDPAIDAEVIALAMSVYRKAGLSNLKLVINSLGDKESRTAHREALIRHFEPRIDEFCSDCQKRLRQNPLRILDCKKDRDHELLKTAPSILDYLNEESKAYFAKVQQYLTDIGIAFEVDPNLVRGLDYYNHTAFEIMSNAEGFGAITTLAGGGRYDGLTEEFGGPKAPGIGFAMSIERLLAALDAENVKVGADEGIDCYIVTLGDKAKDYSVSLLYKLREAGISAEIDYEQKKMKGQFKSADRLNAKYIAVLGEDELNQNQINVKDGKTGDQQAIGLDDFIRFLKTNTES
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y440_CHLPN
Sequence: MATSVAPSPVPESSPLSHATEVLNLPNAYITQPHPIPAAPWETFRSKLSTKHTLCFALTLLLTLGGTISAGYAGYTGNWIICGIGLGIIVLTLILALLLAIPLKNKQTGTKLIDEISQDISSIGSGFVQRYGLMFSTIKSVHLPELTTQNQEKTRILNEIEAKKESIQNLELKITECQNKLAQKQPKRKSSQKSFMRSIKHLSKNPVILFDC
What are the official names of this protein?
Uncharacterized protein CPn_0440/CP_0313/CPj0440/CpB0456.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL14_THET2
Sequence: MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEVKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: EF1A_DANRE
Sequence: MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAGGVGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSTEPPYSQARFEEITKEVSAYIKKIGYNPASVAFVPISGWHGDNMLEASSNMGWFKGWKIERKEGNASGTTLLDALDAILPPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPANVTTEVKSVEMHHESLTEATPGDNVGFNVKNVSVKDIRRGNVAGDSKNDPPMEAANFNAQVIILNHPGQISQGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDNPKALKSGDAAIVEMVPGKPMCVESFSTYPPLGRFAVRDMRQTVAVGVIKSVEKKIGGAGKVTKSAQKAAKTK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LNT_HELHP
Sequence: MLPFYAQWVLESYDKAISPLLVSLLGLFSIASVLFVPKNRRFGVGFFIGMLWFYWISLGLRYFDMSFLIPLVVIACGIFMGFVFYIGLWCECLIVRFAFLLLLSYLTPFGFDWIVPESVFAYSYIGVDKLSFALSILALWILFKYKTWWKLGGVICLVFALDFGLKDSKIQNLPPLKIKLAQSAVSQDFDYRMREAKSIFSEHISDIQKAINEEYDVIILPESAFYVPLDSQYFPYFDSLLEMSHKIVIIVGALREEIHTDGRASYFNSTYKFDKGKVSFYDKVHLVPFGETLPSFLLPLVNTFFQGIGGFSAGKDFGYFDIAEIKFKNAICYEGSNRGFYADYPQYVIVTSNNAWFVPSIEPILQKNLMKYYARLYGSVIFHATNLSPAAIITPFVSSR
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.