PharMolix/UniProtQA huggingface dataset:
Protein: NCAP_I76AK
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRRDGKWVRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRVIPRGQLSTRGVQIASNENMETMDSSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: TPS2_MELLI
Sequence: MSIYDDIFKQFPTIDEWSESNEKIMLEPYTHLGINTAKELPSMVTKAFNHWYQVPQPALDIILQIVGPIHAACLLIDDIQDDSDLRGGNPVAHKVYGVAQTINTATYVCFDAYHKISKLTPFSKSPETTDLWSIINDEIAALHRGQWIDLYWRDSLICPTEEEYLRMIHNKTGAIFRLPIKLLQALSPVDSPPDCFPLVNVVGILVQIRNDLLSLSPDFTKDKGFCEDFSEGKFSFPIIHSVKADSSNSLLIDILRLRPKDEPTKRKALRYMKDQTKSLDHTFDVLCKLEKTAKEELEKLGGNSELSSILELIQVSPIPEIADR
What is the function of this protein?
Terpene synthase that shows monoterpene synthase activity and produces (E)-beta-ocimene as a major product, using geranyl diphosphate (GPP) as substrate (PubMed:32913319).  Shows also sesquiterpene synthase activity as it is able to convert farnesyl diphosphate (FPP) into (E,E)-alpha-farnesene (PubMed:32913319).  Finally, TPS2 can convert geranylgeranyl diphosphate into (E,E,E)-alpha-springene (PubMed:32913319).
What are the official names of this protein?
IDS-like terpene synthase 2, ILTPS2.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: Y698_ARCFU
Sequence: MLCHARLEVESKDPEAVVKALKPDDPEWCSCWADNRIVIEVRVEKIGTLLSALDDYLMNIKMCEGVLEVLG
What are the official names of this protein?
Uncharacterized protein AF_0698.
Protein: PYRF_BACFN
Sequence: MNKQSLFENIKRKKSFLCVGLDTDIKKIPDHLLDDPDPIFAFNKAIVDATADYCIAYKPNLAFYESMGVKGWIAFEKTVNYIKENYPDQFIIADAKRGDIGNTSAMYARTFFEELDIDSVTVAPYMGEDSVTPFLSYEGKWVILLALTSNKGSHDFQLTEDANGERLFEKVLKKSQEWANDEQMMYVVGATQGRAFEDIRKIVPNHFLLVPGIGAQGGSLEEVCKYGMNSTCGLIVNSSRGIIYVDKTENFAAAARAAAKEVQEQMAEQLKAIL
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: PYC_ASPTE
Sequence: MAAPYRQPEEAVDDSEFIDDHHDHLRDTVHHRLRANSAIMQFQKILVANRGEIPIRIFRTAHELSLQTVAIFSHEDRLSMHRQKADEAYMIGHRGQYTPVGAYLAADEIVKIALEHGVHLIHPGYGFLSENADFARKVEKAGMVFVGPTPDTIDSLGDKVSARQLAIRCNVPVVPGTEGPVERYEEVKAFTDTYGFPIIIKAAFGGGGRGMRVVRNQADLRDSFERATSEARSAFGNGTVFVERFLDKPKHIEVQLLGDNHGNVVHLFERDCSVQRRHQKVVEVAPAKDLPTDVRDRILSDAVKLAKSVNYRNAGTAEFLVDQQNRHYFIEINPRIQVEHTITEEITGIDIVAAQIQIAAGATLEQLGLTQDRISTRGFAIQCRITTEDPSKGFSPDTGKIEVYRSAGGNGVRLDGGNGFAGAIITPHYDSMLVKCTCRGSTYEIARRKVVRALVEFRIRGVKTNIPFLTSLLSHPTFVDGNCWTTFIDDTPELFALVGSQNRAQKLLAYLGDVAVNGSSIKGQMGEPKFKGEIIKPKLLDAQGKPLDVSQPCTKGWKQIIDQEGPVAFAKAVRANKGCLIMDTTWRDAHQSLLATRVRTIDLLNIAHETSHALSNAYSLECWGGATFDVAMRFLYEDPWDRLRKMRKAVPNIPFQMLLRGANGVAYSSLPDNAIYHFCKNAKKCGVDIFRVFDALNDIDQLEVGIKAVHAAEGVVEATVCYSGDMLNPKKKYNLEYYLALVDKIVALKPHVLGIKDMAGVLKPQAARLLVGSIRERYPDLPIHVHTHDSAGTGVASMIACAQAGADAVDAATDSMSGMTSQPSIGAILASLEGTEHDPGLNSAHVRALDSYWAQLRLLYSPFEANLTGPDPEVYEHEIPGGQLTNLIFQASQLGLGQQWAETKKAYEVANDLLGDIVKVTPTSKVVGDLAQFIVSNKLSAQDVVDRAAELDFPGSVLEFLEGLMGQPFGGFPEPLRSRALRNRRKLDKRPGLYLEPLDLAAIKNQIREQFGSATEYDVASYAMYPKVFEDYKKFVQKYGDLSVLPTRYFLAKPEIGEEFHVELEKGKVLILKLLAIGPLSEQTGQREVFYEVNGEVRQVSIDDKKASIDNTARPKADVGDSSQVGAPMSGVVVEIRVHDGLEVKKGDPLAVLSAMKMEMVISAPHSGKVSGLLVKEGDSVDGQDLVCKITKA
What is the function of this protein?
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
What are the official names of this protein?
Pyruvate carboxylase, Pyruvic carboxylase, PCB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEMA_SOYBN
Sequence: MTKKKTFIPLLYLTSIVFLPWCISFTFKKSLESWFIDWWNTRQSEIFLNDIKEKSILKKFIEFEELFFLDDMLKECPETHLQNLRTGIYKETIQLIKTHNEDRMNTILHFSTNIICFFILSGYSILGNQELVLINSLVREFIYNLSDTIKAFSILLLTDLCIGFHSTHGWELVIGFVYKDFGFAQNDQIISGLVSTFPVILDTILKYWIFRYLNRVSPSLVVIYHSMND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: RL32_BORBU
Sequence: MAVPKFKPSKSRSRTRRSINMRKKIPQFQECSNCGNLGVRHRICLKCGYYRNNQYLEIGL
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: GLN1B_NEIGO
Sequence: MSIKNAVKLIEKSKARFVDLRFTDTKGKQHHFTVPARIVLEGPEEWFENGQAFDGSSIGGWKGIQASDMQLRPDASTAFVDPFYDDVTVVITCDVIDPADGQGYDRDPRSIARRAEAYLKSSGIGDTAYFGPEPEFFVFDGVEFETDMHKTRYEITSESGAWASGLHMDGQNTGHRPAVKGGYAPVAPIDCGQDLRSAMVNILEGLGIEVEVHHSEVGTGSQMEIGTRFATLVKRADQTQDMKYVIQNVAHNFGKTATFMPKPIMGDNGSGMHVHQSIWKDGQNLFAGDGYAGLSDTALYYIGGIIKHAKALNAITNPSTNSYKRLVPHFEAPTKLAYSAKNRSASIRIPSVNSSKARRIEARFPDPTANPYLAFAALLMAGLDGIQNKIHPGDPADKNLYDLPPEEDALVPTVCASLEEALAALKADHEFLLRGGVFSKDWIDSYIAFKEEDVRRIRMAPHPLEFEMYYSL
What is the function of this protein?
Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I beta, GSI beta.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_CLOK5
Sequence: MKKTLVKSLYRETEKFIDKDIEISGWIRTIRDSKSFAFIELNDGSFFKNVQVVLDDKIENFKEIIKLPISSSLSVEGTLILTPNAKQSFEIKAKKISLEGNSSSEYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAVHKFFQEKDFVYVNTPIITGSDCEGAGEMFRITTMDLNNVPKEEDNSVDFSKDFFGKETNLTVSGQLSAETMALAFRNVYTFGPTFRAEDSNTSRHAAEFWMIEPEMAFAELKDYMDTAEELVKYIINYVLEKAPEEMAFFNSFIDKSLFDRLNNVVNSEFGRITYTEAVDILQKSGASFQYPVEWGIDLQTEHERYLTEKVFEKPIFVTDYPKAIKAFYMRENEDGKTVAAADLLVPGVGEIVGGSQREERLSVLEKRISEFGLNKEDYWWYLELRKYGETKHSGFGLGFERILMYITGMSNIRDVIPFPRTPGSAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_MARN8
Sequence: MDMKQALNRIASNLDLSRDEMKDVMRIVMNGEATDAQIGAFLMGLRLKSETIDEITGATEVMRELATGVTVNAEPLVDIVGTGGDGANLFNVSSAASFVVAAAGGYVAKHGNRGVSSKSGSADLIEKAGINLNMKPEEVARCVEQIGVGFMFAPAHHGAMKHAIGPRRELGCRTIFNILGPMTNPAGVTRQLIGVFTRELCRPMAEVLQRLGAEHIMVVCSKDGLDEISLATVTHVAELKDGEITEYDLTPEDLGIKSQSLVGLSVDGADESLALIKAAFGRSHDETTEKARDMIALNAGAAIYVAGLARTAKEGVDMALDAMGSGLAAGKMSELADFSQCF
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RL18_BOMMO
Sequence: MGIDINHKHDRKVRRTEVKSQDIYLRLLVKLYRYLARRTNAKFNQIVLRRLFMSRINRPPISVSRLARHMKKPTREGLIAVVVGTVTNDVRLYKIPKMTVAALHVTEKARARILAAGGEILTFDQLALRAPTGKKTVLVQGQRNAREAVRHFGPAPGAPRSHTKPYVRTKGHEKARPSRRANV
What are the official names of this protein?
60S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MANC_ECOLI
Sequence: MAQSKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAAKRHSPESDPLMLVLAADHVIADEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGYIRRGEVSAGEQDMVAFEVAQFVEKPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELKKYRPDILDACEKAMSAVDPDLNFIRVDEEAFLACPEESVDYAVMERTADAVVVPMDAGWSDVGSWSSLWEISAHTAEGNVCHGDVINHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQVKRITVKPGEGLSVQMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFADRYGRV
What is the function of this protein?
Involved in the biosynthesis of the capsular polysaccharide colanic acid.
What are the official names of this protein?
Mannose-1-phosphate guanylyltransferase, GDP-mannose pyrophosphorylase, GMP, GMPP.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 2 family.
Protein: TYSY_EHV2
Sequence: MVTHCEHQYLNTVREILANGVRRGDRTGVGTLSVFGDQAKYSLRGQFPLLTTKRVFWRGVLEELLWFIRGSTDSNELSARGVKIWDANGSRDFLARAGLGHREPGDLGPVYGFQWRHFGAAYVDSKTDYRGQGVDQLRDLIGEIKRNPESRRLVLTAWNPADLPAMALPPCHLLCQFYVAGGELSCQLYQRSGDMGLGVPFNIASYSLLTYMVAHLTGLEPGDFIHVLGDAHVYLNHVEPLKLQLTRSPRPFPRLRILRRVEDIDDFRAEDFALEGYHPHAAIPMEMAV
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: TDH_ANASK
Sequence: MKALVKAKREEGIWMQHDVPVPEVGVHDVMIKVTKSAICGTDVHIYNWDEWSQKTVPVPMVVGHEYVGRVEKVGAEVEAFRPGERVSGEGHVTCGFCRNCRAGRRHLCRHTVGVGVNRPGSFAEYVVIPADNVYRIPDDIPDDIAAIFDPFGNATHTALSFDLVGEDVLVTGAGPIGVMAAAIARHVGARHVVVTDVNDYRLDLARRMGASRAVNVAKEDLRAVMSELGMREGFDVGLEMSGNGRAFRQLLEVMNHGGKVALLGIMAGPEPVDWSQVVFKGLQLKGVYGREMYETWYKMVAMLQSGLDLSAVVTHRFSIDDFQQGFDVMRSGRSGKVVLDWGAAR
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_YERPP
Sequence: MLQFTPPLQPATLILRYKRFLADIVTPAGEALTIHCANTGAMTGCATPGDTIWYSTSDNPKRKYPQSWELTQTQTGDWICVNTMRANELVNLAIEKNQIAELSGYNFVRKEVKYGEENSRIDLLLQAEDRRDCYIEVKSVTLLQQQCGYFPDAVTLRGQKHLRELQNRVVNGHRAVLFFAVLHTGIKQVAPARHIDRRYAELLVQAQQAGVEVICYGFQLSPDGIELNTRLPLLLDEMLSSENAE
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: YCF2_PINKO
Sequence: MKKKKGERGGSKEMKKRRSWIIKLEEIQSYQFLCNPWTKSNLMRFLIQILSHRERLIKLFDPRILSTLLLRDLRRSNPYFLVKGIVVLTLSILIYHFNHKSSMIEKKNFYSMKLFPIHNFMELGNETPEEYLKPFTKNWLIFPHLFLSFQLKRSYNRFIEHFDPISFNSGYGRNTNKKDEMISENQGPPSKTHLENNEKDLNLKIDSTLNSTENEYWEPEKDLCEDSFIEREQTKIEIESDLSSKCLSEYYPISWAKELFTEDQRYTEENSFPLERKRFIENFTKSIRYSFFYIWPMDEPCMGGPSATKKPIEDFNLSKRLLKRQQNVFSQYLRDSKSYSLMNRIVDLWKIKTYFEIENSSSNYAIPSDPGWNILNILHNNFRSKTKKIVLEMTDQFTLSITKPSQVHDQIYCNIYYYMNPLYELNKNGSLRSDRIFNHREKLKNQSLWVLLNIIDKADDYLDQIIDKQLSQIDSKNRLEIGTPFNNYRTEALSWYESIRYKIARYSENLFNRFYFINRFSHNLKNQIRTNWIENENLNNVTKDTIDRHSSSWKKIQREWLNRSIIRTDKNINRNLNVYKWSHQTEYFMKYLKHKKNYFQRVFDLIESCTNTNRNKIGWKDYFQFFQHTVKILNSNFDIISNLNSKFDIVISILDSHLNKLKSIDPQLLKKNNLDINDLLDLMGTLIVHLKKLKPFLFLLDDHNLSQRSKLLIDEGTIAPFVPNDIPINPSIIDFFYNEKNRMESFDNTDFSTISNDRENWLNPVKLSDQSSLRASFHGANTLQFFDYLHHPRPNYRKRLPSDMKRIYIKRKNLTYGQLFNLLLIHNNISSLLIGEIGPVHSEKETISLIKSQVSNIFLPKYLQRKRSGEQPFVLIYDLYRSFNLLTQLNPFVRDKRYISSIEEISTTPLTKEQIVNLEKTFCQPFFNRSDSEENNLDKCLKRGFSSNVGLIQTRSYQDDLLSEIFSNKNQEMFHRIQDWFVTKSFKNIIGNEGIDGRSTLSNSSKEEQKIKPSPHFNEPAKKQEMYRISQIDSILSKWDLFKTYMPWFFTSAWCKYLENMLLYTLPEILLHGSNPFVSILQDIKHNIMLKWNILWELSHPLWEPIKWKLRTNLTNLLNFRFRTTLMNKFFSSCEDCFIEETSDREWTHLRLLNARRYEYGILIPFFVLTYSILRYFKVIYSAFINLKIDFELIQYLEDPSYVIELQKLINPPVYNYLLYYIDIESLPSTKRKRKNRKLNLLITIIRELNGLCSSMDISEKEMEILVQFLMTEKNLSQFESNMTVSHIFLKKEFGDQITGQPGLIHLRYLAHTYQKGLMNYELNPFCLAENRIFLAFYQKITSSQILCQPNPKMPFSFHSGSLFSKGILLIGPMGTGRSYLIKSLAADSYVPLIRISLKKLLYGKFLYYPDPGRIPTEFNTFWRDTIDHFHITFELAKRMSPCIIWIPNIHELNVNDTITHLFGLGFTDSFLGLLLNYISRGGEKDSIRNILFIASTHIPQRVDPALIAPNRLDSSINIRMLVIPQRQREFPILLCSKGLYSEKEVSCPDEFGSITIDSDARDLAALANEALITSITRKKSVIDTNTIRYAIYSQICHLQSMDNQVGSSQNDERLIYKVGKAFIQNTLRRNSPMNPLSTKKELWKKRFCYLSEWYLEPSIAETTMKELTILPHILGCLAGSAARDSWSISERNRENWIPLDKFAEHDLDLASSLLESILVEFPFSRLGICRGKSDKDQSKFDKDQITFVPQPKMRNNHMIRFLKEYELKFTIATKKMYRDMDMDEELIKSVVWTPRTWRLSFLRSNRFDHTKTPNSLGSSYRFGSKKKAQIERSKFARQYPRQYKSSEKPTFCRGKRFLWDPFLFQEQRPVFSRREFFADEELLKRLYITYGSRRLLAKPNFFPKQSFQSAFHRYDSKYGINPGLIMNSWKPLSLRHRHIEHFKHIQEIGIHLERIQPYSSPYLYKCWLIENSRERVDRFQSLIHRQKRWLGTNSLLSNESFLYNTLFESYQYLSNLFLSNRVLLDQITKTLLEKECLFPNEIEHSIYTTGLRFDISWENLE
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: CINA_STRS2
Sequence: MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNEGRLLSTLEVASKRSNMVVLCGGLGPTEDDLTKQTLATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAMFSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADVIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEDILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVVGQLGIESGWLSEEADCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: S2547_HUMAN
Sequence: MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYTGIWHCVRDTYHRERVWGFYRGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVLRLARGLLT
What is the function of this protein?
Uncoupling protein which may catalyze the physiological 'proton leak' in liver.  Overexpression induces the dissipation of mitochondrial membrane potential.
What are the official names of this protein?
Solute carrier family 25 member 47, Hepatocellular carcinoma down-regulated mitochondrial carrier protein.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SFSA_PSEPK
Sequence: MRFSPSLEQGRLLRRYKRFLADIELASGEQMTIHCPNTGSMLNCMREGGQVWFSRSNDPKRKLPGTWEISETPQGRLACVNTGRANALVEEALRAGTITELAGFTALKREVAYGEEGSRIDFRLEFEGAPAYVEVKSVTLGYPDTAVAAFPDAVTQRGAKHLRELAKLARQGVRAVQLYCVNLTGIDAVRPAEEIDTAYAQALRAAVADGVEVLAYGTRLDAEGIVIDRRLPVLLTP
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: AKT2_ALTAL
Sequence: MQQPIIGVGHSMGGCQIATLSVTSRRMFSTMILLDPAIGPPDMGLATLDLGQLTLRRRTQWPTREDAEKALRTSFSTWDSQVLNLLIKHSIHSDKQSIEMEDGPVSLVTGRYQELVNYIKPSFIRSGKVNGQELIHQTGPVDMYHMLGLVTCSALYLCGGESTLSVPRVRDLWLNRTAKLSYSKEPGETRKVDERIVPDTGHFLPMEEPKKCADIIADWIEKDKCIAWNCCVGKRGKTWCELSNASKEMSAEAWMKYLQSKL
What is the function of this protein?
Abhydrolase domain-containing protein; part of the gene clusters that mediate the biosynthesis of the host-selective toxins (HSTs) AK-toxins responsible for Japanese pear black spot disease by the Japanese pear pathotype (PubMed:10432635, PubMed:20348386).  AK-toxins are esters of 9,10-epoxy 8-hydroxy 9-methyldecatrienoic acid (EDA) (PubMed:22846083).  On cellular level, AK-toxins affect plasma membrane of susceptible cells and cause a sudden increase in loss of K(+) after a few minutes of toxin treatment (PubMed:22846083).  The acyl-CoA ligase AKT1, the hydrolase AKT2 and enoyl-CoA hydratase AKT3 are all involved in the biosynthesis of the AK-, AF- and ACT-toxin common 9,10-epoxy-8-hydroxy-9-methyl-decatrienoic acid (EDA) structural moiety (PubMed:10432635, PubMed:10975654, PubMed:22846083).  Part of the EDA biosynthesis occurs in the peroxisome since these 3 enzymes are localized in peroxisomes (PubMed:20348386).  The exact roles of the 3 enzymes, as well as of additional AK-toxin clusters enzymes, including AKT4, AKT6 and AKTS1, have still to be elucidated (PubMed:10432635, PubMed:10975654, PubMed:22846083).  The Cytochrome P450 monooxygenase AKT7 on the other side functions to limit production of EDA and AK-toxin, probably via the catalysis of a side reaction of EDA or its precursor (PubMed:24611558).
What are the official names of this protein?
Abhydrolase domain-containing protein AKT2, AF-toxin biosynthesis protein 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.
What are the subcellular locations of this protein?
Peroxisome. Note=The peroxisomal location requires the C-terminal tripeptide peroxisomal targeting signal.
Protein: ZN420_HUMAN
Sequence: MARKLVMFRDVAIDFSQEEWECLDSAQRDLYRDVMLENYSNLVSLDLPSRCASKDLSPEKNTYETELSQWEMSDRLENCDLEESNSRDYLEAKGKMEKQQENQKEYFRQGMIIYDKMSIFNQHTYLSQHSRCHSTEKPYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLTRHQKVHTGEKPYECKECGKAFTQNSQLTLHQRLHTGEKLYECKECRKVFTQLSQLILHKRIHTGEKPYECKECGKAFICGSQLSQHQKIHNGEKPYECKECGRAFIRGSLLMQHQRIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSHGSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGEKPYQCKECGKAFTRGSQLTQHQRIHISEKSFEYKECGIDFSHGSQVYM
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 420.
What are the subcellular locations of this protein?
Nucleus.
Protein: RRF_RICRS
Sequence: MDKEHLKKNLQEKMEKALKVLDHELKGLRTSRASVNLLDSVTVEAYGSKMPLSQVASLSTPDARTINVQVWDKSMVSSVEKGITIANLGLTPATDGQLIRLPIPALTEERRTELVKLAHKYGEDTKISLRNIRRDGNEVLKKLEKDNVIAKDEHHSLSEQVQKLTDDYSSKVDSVIKQKEQEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_CHESB
Sequence: MTLKARVIPCLDVKDGRVVKGVQFVDLIDAGDPVEAATAYDAAGADELCFLDITASHENRETIFDVIARTAEQCFMPLTVGGGVRQIPDIRRLLLAGADKVSINTAAVKEPEFVARAADKFGDQCIVVAIDAKKVSPPGQADRWEIFTHGGRNPTGIDAVEFARRVVDLGAGEILLTSMDRDGTKAGYDIALTQAVADAVRAPVIASGGVGTLDHLVEGIRDGHATAVLAASIFHFGTYTVAEAKRYMADAGIPMRLDAANAEGNAHE
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFS2_SCHPO
Sequence: MERAENARIIQKPMTRRTVDYGSGLSKYIVNRHLRSNRYHIHVPRPNPNQIINLYPPYEYKYNNTSSLCTKYIHTSANKARHVINVVRWTPDGRRLLTGSSTGEFTLWNGLTFNFELINQSHDYAVRCAEWSTDGRWLISGDGGGMVKYFEPNLNNVKIVQAHEMEVRDVAFSPNDSKFVTASDDGSLKVWNFHMSTEELKLTGHGWDVKTVDWHPSKGLLASGSKDNLVKFWDPRTGTCIATLHGHKNTIMQASFQKNFGSNYLATVSRDSTCRVFDLRAMKDVRVLRGHEKDVNCVTWHPLYPNLLTTGGSDGSVNHYSLDEPPLLSQQKYHEKHPNVTLSASSYLLYPTAEIPFAHDLGIWSMQYHPLGHLLCTGSNDKTTRFWSRSRPDDKESTMDRHHLGEEQSEAMLSQRKAAIEEDDNYEPDENPLTETLANAHNPQFSGVLNLPGLGTMPSFPSPYQHGQPQIPGMLHASLSNSYAEPSTQNSFIPGLTSKSQDGYPQNYR
What is the function of this protein?
Required for 3'-end cleavage and polyadenylation of pre-mRNAs.  Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.
What are the official names of this protein?
Polyadenylation factor subunit 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RU1C_BRAFL
Sequence: MPKYFCDYCDTYLTHDSPSVRKTHCNGRKHKENVRVYYQKWMEEQAQQLIDQTTAAFQAGKIPNNPFPNAAGQVGNEPGAKVLPPAILQAAAFQAGKIASNPFPTSQAGPGPQGGGTMIPPPPSLQGPGGPGSAPAPPRMPGPLLMTPPPGAAAPGMAPPGAPTLPQPARGPILSVGAVMGPRLCKHSYHINKALFLIKIHTLQKATQSQLVVYKTVEKSK
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NODP_AZOBR
Sequence: MPTLPNDLRLLEAESIAILRETAASFTKPVLLYSIGKDSGVLLHLARKAFHPSPVPFPLLHVDTGWKFREMIAFRDATVRRLGLTLIVHRNEEGHARGIDPIRSGSALHTRVMKTEALRQALDRHGFDAAIGGARRDEEKSRAKERVFSIRNAAHAWDPRDQRPELWRLWNPRIQPGESVRVFPLSNWTELDVWRYVAAQSIPVVPLYFAAERPVVHRSGALIMVDDGRLPLNPGETPEMRRVRFRTLGCYPLSGAIDSDAATVEDIIVEMRASRTSERQGRLIDGDEPASMERKKREGYF
What is the function of this protein?
Proposed to provide activated sulfate for transfer to nod factor.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Nodulation protein P, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: LIPR3_HUMAN
Sequence: MLGIWIVAFLFFGTSRGKEVCYERLGCFKDGLPWTRTFSTELVGLPWSPEKINTRFLLYTIHNPNAYQEISAVNSSTIQASYFGTDKITRINIAGWKTDGKWQRDMCNVLLQLEDINCINLDWINGSREYIHAVNNLRVVGAEVAYFIDVLMKKFEYSPSKVHLIGHSLGAHLAGEAGSRIPGLGRITGLDPAGPFFHNTPKEVRLDPSDANFVDVIHTNAARILFELGVGTIDACGHLDFYPNGGKHMPGCEDLITPLLKFNFNAYKKEMASFFDCNHARSYQFYAESILNPDAFIAYPCRSYTSFKAGNCFFCSKEGCPTMGHFADRFHFKNMKTNGSHYFLNTGSLSPFARWRHKLSVKLSGSEVTQGTVFLRVGGAVRKTGEFAIVSGKLEPGMTYTKLIDADVNVGNITSVQFIWKKHLFEDSQNKLGAEMVINTSGKYGYKSTFCSQDIMGPNILQNLKPC
What are the official names of this protein?
Pancreatic lipase-related protein 3, PL-RP3.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.