PharMolix/UniProtQA huggingface dataset:
Protein: MUTA_MACFA
Sequence: MLRVKNQLFLLSPHYLKQVKESSGSRLIRQRFLHQQQPLHPEWAALAKRQLKGKNPEDLIWHTPEGISIKPLYSKRDTTDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTSKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKSSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLQKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQSV
What is the function of this protein?
Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.
What are the official names of this protein?
Methylmalonyl-CoA mutase, mitochondrial, MCM, Methylmalonyl-CoA isomerase.
What is the protein family that this protein belongs to?
Belongs to the methylmalonyl-CoA mutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion. Cytoplasm.
Protein: RS16_ALKMQ
Sequence: MAVKIRLKRMGAKKRPFYRIVVADARAPRDGRFIEEIGYYNPVSEPKEIKIDGEKAEKWLGNGAQPTDTVKYLFKKNGIIK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: YIHY_ECO45
Sequence: MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISAYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAEKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS6_METEP
Sequence: MLKTRIIPCLDVKDGRVVKGVQFLELRDAGDPVESAKAYDAAGADELCFLDITASHEARGTLLDVVSRTAEACFMPLTVGGGVRTVADVRTLLLAGADKVGINTAAVKNPDFVAEAAEKFGDQCIVVAIDAKRVSGPDEAARWEIFTHGGRNPTGIDAVEFARTVSERGAGELLVTSMDKDGTRSGYDIALTRAIADAVRVPVIASGGVGGLDDLVAGVRDGGASAVLAASIFHFGHHTVGEAKAHMAAAGLAMRLDP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD54_HUMAN
Sequence: MYTLHTKRVKAAARQMWTSNLSKVRQSLKNVYHKCKIRHQDSTGYPTVTSDDCNQDDDSYDGKMNLPVVLQDVKTAQVELFSQMTDIVHMIPKVQEKTDLYQKQMEVLETRMNVNEDKQCTTTKDILSMKEDIKALKKKVTELEIQNSCSTIHCLEILEGERGKEITELLYKLIQPATLKNTLASTDMEISSAEPEKVPSYPKSTDHLEKKTISPQMKTLKKRNHQNASRSFEKAKPNIYIYPDFSTWIKLTFVHGGKWTFFLSATKLEEFIQWLLSRPTILPEEPQVITQRYCPFTGPILSLTTICLSIFNNIYGFICSLKEEVTRL
What are the official names of this protein?
Coiled-coil domain-containing protein 54, Testis development protein NYD-SP17.
Protein: RL7_CLOK5
Sequence: MSKEEIIQAIKGMSVLELNELVKACEEEFGVSAAAPVAVAGGAAAGGGDAAEEKTEFDVVLKASGSEKIKVIKAVREVTGLGLKEAKALVDGAPKPLKEAVSKEDAEAIKAKFEEIGAEIELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TRUD_XANCB
Sequence: MSDSPVLPRAHGAAVLTAAMRSVAEDFQVDELPAFDASGEGEHLLLSVRKRGQNTAYVAKRLAQWAGIAEMGIGYAGLKDRHAVTTQRFSVHLPKRIAPDLSALDDDDMQVVEHTWHNRKLQRGALHGNRFVLTLREVVGDQTAIDARLHAIAARGIPNWFGEQRFGRDGGNVAAALAMFGYTRQLDGTLAPAPKRRLRNDQRSLLLSAARSALFNQVLTARVEQGDWDAPLDGEAWMLDGSRSVFGPEPWSEVLAERLARFDIHPSGPLWGAGELRCSADAAAIEQAALSDPQSLALRTGLEAAGLKQERRALRLRPQALAHAWLDAQTLQLTFALPPGCYATAVLWELGDVVDAARVAPQSRSEG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: PSBN_PLETE
Sequence: METPAFFFTTFLGCLLLSITGYSIYVGFGPPSKQLRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: WNT2_DIDVI
Sequence: MNSSSLFGIWLSVPLILSWVTPQVSSSWWYMRAVGSSRVMCDNVPGLVSRQRQLCHRHPEVMRSIGLGVAEWTAECQHQFRQHRWNCHTLDRDHNLFGKVLLRSSREAAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGTSKDSKGTFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWKKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSRVTRMTKCECKFHWCCAVRCQDCLEVVDVHTCKAPKSPDWVAPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MURA_RICM5
Sequence: MHKLIIHGGKPLKGSINISGAKNAVLPIMAASILTDKLHITNVPKLTDVGTMKDLLRSHGADIEIIEHQDEFELIINTENINNFTADYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCAIGARQVDLHIAVLKAMGATIEIEDGYINASSKGRLKGTHFVFDKVSVGATINAILAAVLTEGETVLFNCGREPEIVDLCNCLITMGADIAGIGTSEITIKGKDSLNKASYKVLSDRIEAGTYMFAAAITKGDVKICGIDYHIVENIALKLIETGIKVVPINNGVQVTYEGKLNSVDLETNPYPGFATDLQAQFMSLMTLSSGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGVEMLKGAEVMASDLRASVSLILAGLSTNSKTVLHRIYHLDRGFQDLEKKLSNCGADIKRV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_PSEPK
Sequence: MYLQLLKSLNRLHPRAWDFVQLSRMDRPIGIYLLLWPTLSAVWIAGNGSPTLANVLIFGLGVVLMRAAGCCINDFADRKVDGHVKRTADRPLASGRVRPREALTLFAILVGVSFLLVLCTNSRTVWLSFGAVALAFCYPFMKRYTYYPQVVLGAAYSWGIPMAFTAAGGELPAGAWLLYIANLLWTVGYDTYYAMVDRDDDLKIGVKSTAILFGDADRSIILTLQLLSLGCLLLAGSRFDLGGWFHLGLLGAAACFAWEYWSTRKLDRESCFKAFLHNHWAGMLVFIGVVLDYALR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELO_BACAC
Sequence: MTKNNEAGWNLDHSYTTLPQSFYTEIPPTPVSSPELVKLNHSLAISLGFNPEELKKEAEIAIFAGNALPEGAHPLAQAYAGHQFGHFNMLGDGRALLIGEQMTPSGKRFDIQLKGSGPTPYSRRGDGRAALGPMLREYIISEAMYALDIPTTRSLAVVTTGEPTYRETKLPGAILTRVASSHIRVGTFQYAAARGSIEDLQSLADYTIKRHYPEIEAHENRYTALLQEVIKKQASLIAKWQLVGFIHGVMNTDNITISGETIDYGPCAFMDNYDQGTVFSSIDTQGRYAYGNQPYMAAWDLARLAESLIPILHEDEEEVLKIAQDEISKFSVQYEKQWFLGMKKKLGLFSNEEQDQSLIEQLLKMMEKFKADYTNTFRSLTLNTIENTALFESPEFKEWYKLWQSRLERQEESKENAYEMMKNNNPSIIPRNHRVEEALEAAVTNGDYSVMEKLLEALSNPYAYATEQEEYCVPPVPTNRPYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RS3_NATPD
Sequence: MADEHQFIHDGLQRTQIDEFFSEELSRAGYGGMEVAKTPMGTQIVLKAEKPGMVIGKGGKNIRKITTTLEEEFGLEDPQVDVQEVDEPDLNAQIVADRLANALERGWYFRKAGHTTIDRIMESGALGAEIILSGKVTGARSRVEKFNRGYIKHNGEPAESIVDSGVGTAVMKLGTIGVQVKIIPPEAELPDDFEVYEDIEVEDFVEEPEGDVEELLEAPEDAEAESVGADPEEVIEEETEAEAVEEVAEEEIIDEEGVEAETGDAPTSPPDAAEEPDEALDEDVEAEAEELLDEMEDETTDEEET
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RK20_NYMAL
Sequence: MTRVRRGYIARRRRRKIRLFASSFRGAHSRLTRTATQQKIRALVSSHRGRGRQKRDFRRLWITRINAVTRENGVPYSRLIHDLRKKQLLLNRKILAQIAISNRNCLYMISNDIIK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL23_BORA1
Sequence: MNAERLMQVLLAPVVTEKATFVAEKHQQIAFRVVADATKPEIKAAVELLFKVQVEAVQVLNRKGKVKRFGRFVGRRRNERKAYVSLKEGQEIDFAEVK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: E313_ADECT
Sequence: MAMTEESMDQVEVNCLCAQHAQTCTRPRCFAKEGLCANWFYNPALAFEGFDIPDSYQEGHGVDIEVKCSHHSSKLCHNGHDMICSYSRLGSHINIRCICNKPRPHMSLIEAACSMYNLN
What are the official names of this protein?
Early E3 13.3 kDa protein.
Protein: ITB1A_XENLA
Sequence: MAHYPVFTVGLLTCLVLCINAQQGGTECLKANAKSCGECIQAGPNCGWCTKVDFLQEGEPTSARCDDLAALKSKGCPEDDIQNPRGRKQKLKDIPITSKGKGERMDPANITQLRPQQMVFELRSGEPQTFNLTFRRAEDYPIDLYYLMDLSFSMKDDLENVKSLGTALMTEMEKITSDFRIGFGSFVEKTVMPYISTTPAKLINPCTSDQNCTSPFSYKNVLNLTKDGKLFNDLVGKQQISGNLDSPEGGFDAIMQVAVCGEQIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGKCHLHENMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEDFQPVYQELKNLIPKSAVGTLSSNSSNVIQLIIDSYNSLSSELILENSKLPEGVTISYKSFCKNGVKGTGEDGRKCSNISIGDQVEFEISVTAHKCPKKGQAESIKIKPLGFNEEVEIILQFLCECDCQDKGTPNSPECHFGNGTFECGACRCNDGRIGKECECSTDEVNSEDMDAYCRRENSSEICSNNGDCICGQCVCKKRDNPNEVYSGKYCECDNFNCDRSNGLICGGKGICKCRVCECFPNYSGSACDCSEDTSTCMAKNGQICNGRGICDCGRCKCTDPKFQGPTCELCQTCVGVCAEHKECVQCRAFQKGEKQDVCMEQCMHFNISLVDSREELPQPGQAEALTHCKEKDAEDCWFYFTYSVDSKNEVMVHVVKEPECPSGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK
What is the function of this protein?
Beta integrins associate with alpha subunits to form receptor complexes that recognize the sequence R-G-D in a wide array of ligands.  May be involved in osteoblast compaction (By similarity).  May play role in myoblast differentiation and fusion during skeletal myogenesis (By similarity).
What are the official names of this protein?
Integrin beta-1-A.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, invadopodium membrane; Single-pass type I membrane protein. Cell projection, ruffle membrane; Single-pass type I membrane protein. Melanosome. Cleavage furrow. Cell projection, lamellipodium. Cell projection, ruffle.
Protein: PNP_DESRM
Sequence: MSENQVLIREISLGGRTLTLETGRMAKQASGAVLVTYGETVVLVTATVAKNTRDIDFFPLTVDYEERLYAVGKIPGGFIKREGRPSEKAILSGRLIDRPIRPLFPKHMRNEVQVVATVMSVDQDNAPEIAAMIGASAALHISKIPLKKPIGGVIVGRVDGQFVINPMVRQAENSDMHLVVAGTDDAVMMVEAGAKEVPESEMLEGIMYGHEKVKEIVKFIEDFRTEALGMGLAFEKMEIPEPQFDSNMSEAILTIAEEAIREAVLHCSREKLTKKQREVYMDEVMSGLQEKFLEQFPENPKEVTMLIEKAEKKVVRRIITHDKLRIDGRAIDEIRPISVEVGVLPRTHGTGLFTRGQTQILSVATLGSISEEQILDGLGVEESKRYMHHYNFPPFSTGETKPMRSPGRREIGHGALAERALEPMIPPEEVFPYTIRVVSEAIESNGSTSMGSVCGSTLSLMDAGVPLKAPVAGVAMGLIMEEDQFTVLTDIQGLEDHLGDMDFKVAGSANGVTALQMDIKIPGITREVFEQALEQAHRGRMFILGKMLEVLSTPRAEISVHAPAIIRTSIHPDKIRDIIGPGGKIIKKLVEETGADIDIEDDGRVFIAAVDREKGKRALEIIQSITAEVQVGKLYNGKVTRVTDFGCFVEVIPGVMGLPGKEGLVHISQLAFQRVEKTEDIVKEGEVIAVKAIGYDQQGRLKLSKKEAMRDMGLAPAESTSEQPEKRERRPFSRPKATKE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNP4_PYRFU
Sequence: MAKYNEKKEKKRIAKERIDILFSLAERVFPYSPELAKRYVELALLVQQKAKVKIPRKWKRRYCKKCHAFLVPGINARVRLRQKRMPHIVVKCLECGHIMRYPYIKEIKKRRKEKMEY
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.  The RNA is catalytic, but its KM for pre-tRNA is 170-fold decreased in the presence of the 4 known protein subunits (Rnp1-4).  The protein subunits also decrease the amount of Mg(2+) needed for activity.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y032_RICTY
Sequence: MALFPRGILIALVLSFVLNLGLVTKIHAKDTLDSIIDILSGLTCETQGVGDLMRTEFSHTCIVAPFFTFAVMNLVSPVLYMNTFLKLKINDSDLFNDSNFGNFPGGQCTRENRIDPKNPELHFALCSNAKLIVSRAKSVTESALAIAKAVLTWSDPWDDIKQAWENKKKEYHIPYRGKPGDDGFAFDVGFPVIYWKVIQDRDRICVSTKGFTGDVPVGCKYMKEPFPKSIYNSFIDVEDKNFIKDSTNDTPSDPLALVSCSAAGDGCYQKAYNASKTAIVMTSPLIECIRQMIARLLISKDVCSFDNVDQVVNLASRQDSALFQFQVGMHKIVTAFLTLYVMFFGFKLLLAGKVPPKSEYINFILKIIFVTYFSIGININPSNGSQYDRLDGMIQWVFPFLLNGISGLANWVMNAAPSGLCKFNNISYDKSVSYIALWDALDCRVAHYLGLDILSTLLVENSYRSHDFLNFDFFSFSAPPYIYLIIPAIISGNMMLVSLALSYPLLVISVAAFMVNATIMCMISIVILGILAPLFVPMFLFAYTRNYFDSWVKLMISFLLQPMVVVTFMITMFAVYDYGFYGKCQYKSKLIHNSIEDKMQGGIKSKRDVLIFYINNDWDDTSQYPDKDSVESCKNSLGYMLNNPINTAFNFAKDNISEIVNSKPGETTTDEFLSKFQFLSGVVLGPGMFFMSPKVLFEKIKNIFLALITACFTLYLMYNFSSQLAEFAADMTEGVALNNVAIKPQAIFKAAMAALANAGTATKGIDQIASRGGGGGARDLIGAKGLVSDNIASSGGAVGDNIASSGGAVGDNIAVSGAASTPTVTTTTASSSIANSMTKTIGDDVRSDIVTPHASTTAVPQHSSINTTIPTSVSPNIKSTSLKEIIRDNQENEKEIDNTTRAQEKIKSSSKVSGLIDYSFNLKEHDNPTGIKQIRENAEIRDKRVEVEKAWNELVASGGGRIRDQQSEETSEQRTNAEKKWNEFVDSGVVTEIREIDNSVNNKLADKLDKSEKSKIEENKNIENNIKVYNTNTLPQEKVNNTDKSSGLIDYSFNLKEHDNPTGVKQIRENAEIRDKRVKVEKAWNELVASGGGRVKEQAGGKITERRANAEKVWDDLVKSGVVKEKKDNSSNENS
What are the official names of this protein?
Uncharacterized protein RT0032.
What is the protein family that this protein belongs to?
Belongs to the TrbL/VirB6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BMT1_KOMPC
Sequence: MVDLFQWLKFYSMRRLGQVAITLVLLNLFVFLGYKFTPSTVIGSPSWEPAVVPTVFNESYLDSLQFTDINVDSFLSDTNGRISVTCDSLAYKGLVKTSKKKELDCDMAYIRRKIFSSEEYGVLADLEAQDITEEQRIKKHWFTFYGSSVYLPEHEVHYLVRRVLFSKVGRADTPVISLLVAQLYDKDWNELTPHTLEIVNPATGNVTPQTFPQLIHVPIEWSVDDKWKGTEDPRVFLKPSKTGVSEPIVLFNLQSSLCDGKRGMFVTSPFRSDKVNLLDIEDKERPNSEKNWSPFFLDDVEVSKYSTGYVHFVYSFNPLKVIKCSLDTGACRMIYESPEEGRFGSELRGATPMVKLPVHLSLPKGKEVWVAFPRTRLRDCGCSRTTYRPVLTLFVKEGNKFYTELISSSIDFHIDVLSYDAKGESCSGSISVLIPNGIDSWDVSKKQGGKSDILTLTLSEADRNTVVVHVKGLLDYLLVLNGEGPIHDSHSFKNVLSTNHFKSDTTLLNSVKAAECAIFSSRDYCKKYGETRGEPARYAKQMENERKEKEKKEKEAKEKLEAEKAEMEEAVRKAQEAIAQKEREKEEAEQEKKAQQEAKEKEAEEKAAKEKEAKENEAKKKIIVEKLAKEQEEAEKLEAKKKLYQLQEEERS
What is the function of this protein?
Beta-mannosyltransferase involved in cell wall biosynthesis.  Involved in the beta-mannosylation of outer chains of N-glycans (By similarity).
What are the official names of this protein?
Beta-mannosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the BMT family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: DAPA_METCA
Sequence: MIQGSIVALATPMEPDGRLDVPGLRRLVEFHIEQGTDAIVAVGTTGESATLDEEEHTEVIRLVVEQAAGRIPVIAGTGANATTEAIRLTARAKAVGADACLLVTPYYNKPTQEGLYRHYLAVAEAVDIPQILYNVPGRTGCDMLPATVGRLAQVPGIVGIKEATGKLERLAEIRALCPEGFALYSGDDATACEFCLSGGNGVISVTANVAPRLMQEMCRAAIAGDRATAEAINRRLEALHHDLFIESNPIPVKWALHEMGLIQEGIRLPLTWLAASCREAVRQAMRQAGVL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBLC_ASPCL
Sequence: MHLSFGSLFACLLASSTAVASAPPSNFDVANFKSADIIKRDVAVIGGGSAGTYSAISLKDKGKSVILIEKKGRLGGHAETYIDPATGTPVDMGVLVFHNITVVKDYFKRFDIPLNRADDFMKSEFYFDFRTGRAVTPTFTPQAEEVSAAFAAYLAQYSKYPGLRNGTILPSPVPEELYMPFGKFVEKYGIQAAIPSMYYFNPGVGDILSNPVIEQFRYWSSDMVRSVATGFLGPVRRNVSELYTRAEAELFQSSSLLLSSEVVHALRADGESGVMLIVRTPAGRKLILAKKLLIAFPPKLDFLAPFDLSATEKSLFGKYIDAGYYVGLVKNSGLPNNTSISNAAQGHTDFTFPYLPAAYSFAPSAVPGLQLVTYATGQTTKSLPLSDEAVKADIINTIKRIQKQNPDKFTSTEPEFVTFASHAPYNLQVRAEDIRDGFYDKLYTLQGQRNTHWTGAAWKGEDSSLLWTYSEEIVVPQVIEGL
What is the function of this protein?
FAD-dependent oxidoreductase; part of the gene cluster that mediates the biosynthesis of the sesterterpenes ophiobolins, fungal phytotoxins with potential anti-cancer activities (PubMed:23324037, PubMed:27116000).  The first step of the pathway is performed by the sesterterpene synthase oblA that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylfarnesyl diphosphate (GFPP) and further converting GFPP into ophiobolin F, respectively (PubMed:23324037).  Other sesterterpenoids (C(25) terpenoids) are found as minor products of oblA (PubMed:23324037).  It is expected that ophiobolin F is then oxidized to ophiobolin A via ophiobolin C and ophiobolin B intermediates by the combined action of the cytochrome P450 monooxygenase oblB and the FAD-dependent oxidoreductase oblC (Probable).  Although oblB catalyzes multistep oxygenations at C5 and C21/C7 in a relatively efficient manner, it is unable to convert ophiobolin F to ophiobolin C and produces instead several unexpected derivatives (PubMed:27116000).
What are the official names of this protein?
FAD-dependent oxidoreductase oblC, Ophiobolin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the beta-cyclopiazonate dehydrogenase family.
Protein: IOLC_HALH5
Sequence: MTYELSTDREFDLIAIGRACIDLNAVEYNRPMEETMTFSKYVGGSPANIVIGSSKLGLKAGFIGKIADDQHGRFIESYMRGVGVDTSNLVVDQEGHKTGLAFTEIKSPEECSILMYRQDVADLYLSPEEVNEAYIRRSKLLLVSGTALSKSPSREAVLKAIRLAKRNDVKVVFELDYRPYSWETPEETAVYYSLVAEQSDIVIGTREEFDVLENRTEKGDNDETIRYLFKHSPELIVIKHGVEGSFAYTKAGEAYRGYAYKTKVLKTFGAGDSYASAFLYALISGKGIETALKYGSASASIVVSKHSSSDAMPSVEEIEALIEKDETITIA
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase, 2-deoxy-5-keto-D-gluconate kinase, DKG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: JAL31_ARATH
Sequence: MAQKVEAKGGKGGNQWDDGSDHDAVTKIQVAVGGMGIQYIQFDYVKNGQTEQTPLRGIKGSTIPTDPFVINHPEEHLVSIEIWYKPDGLIQGLRFISNKKTSRFIGYDRGTRSFLQVQDKKIIGFHGSAGDNLNSLGAYFAPLTIPLTPAKPLPALGSDDGTAWDDGAYVGVKKVYVGQAQDGISAVKFVYDKSPEEVTGEEHGKSTLLGFEEFVLDYPSEYIIAVEGTYDKIFGSDGSVITMLRFKTNKQTSPPFGLEAGTAFELKEEGHKIVGFHGRADALLHKIGVHVRPVSN
What is the function of this protein?
Polymerizer-type lectin that may facilitate the correct polymerization of BGLU23/PYK10 upon tissue damage.  Activates BGLU21, BGLU22 and BGLU23.
What are the official names of this protein?
PYK10-binding protein 2, Jacalin-related lectin 31, Jasmonate inducible protein isolog.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: RS27_BOVIN
Sequence: MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for proper rRNA processing and maturation of 18S rRNAs.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: IF2_ALKCK
Sequence: MSKVRIYEYAKANNVQSKQLIESLKSMGVEVSNHMSAIDEETLNKAKQAGKPAAAKGQGSTSNQKQNSQNQRSNQGQKQRPQNNQQNQGQKQRPQNNQQSQSQGQTKRPSQASNNQSGAAKSQAGKPNQNRGGNRPGGQGRPGSNNRRPGNNQNRRNHGNRGGKRRPQSKVNHQQMPLPEKITISGSHTVSELAAKLHREASELIKKLIGLGVMATINQELDKDTIELLAADYGVEVEEEVIVDELDIELYDREDKEEELKERPPVVTIMGHVDHGKTTLLDSIRNTKVTAGEAGGITQHIGAYQIEHSGKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTKEAISHAKAAEVPIIVAVNKIDKETASPDRVMQELTEFELVPEAWGGDTIFVNVSALTGEGIDELIEMILLVAEVEEFKANPDKLATGTVVEAQLDKGRGPVATLLVQSGTLNVGDAVVVGSTFGRVRALVNDVGRRVKTAGPSAPVEITGLNEVPQAGDRFQAFEDEKKARQLGEGLMARYREQNLTASSKVSLDDLFNQIQQGDVKDINVIIKADVQGSVEAMKGSLEKIDVAGVKVNIIHTGAGAITESDIILASASNAIVIGFNVRPDVNAKRVAEAENVDIRLHRVIYNAIDEIEQAMKGALDPEFEEKVIGQVEVRTTFKVSKVGTIAGSYVTEGKITRNSSVRLIRDGIVIYEGELNALKRYKDDAKEVQAGYECGITLDKFNDIKEGDMIEAYVMEEVKRA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.