PharMolix/UniProtQA huggingface dataset:
Protein: GBRB2_MACMU
Sequence: MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKIFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
What is the function of this protein?
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity).  Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity).  The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity).  The alpha1/beta2/gamma2 receptor and the alpha2/beta2/gamma2 receptor exhibit synaptogenic activity (By similarity).  Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit beta-2, GABA(A) receptor subunit beta-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
Protein: Y663R_PBCVN
Sequence: MNEVTRTNQVDKDFSKLTFKLSKHKTKKDKKYEDVSKFSTLHEAVNGNLQNFEMKKSKLQNGANTKKSDEKLKQLEEEEINYLLDTIPFIKEYDNKETVKETTDEQNTIFQIKSKNTNTNTFRKYLFHVEKINNNTTLDAVTERETIDQIFTCTCGGQMEVWITSTQSDLVCNECGLTQPYIETYTGKESNEGMAYKRINHLAECLNALQGKEGTNVPHEVVDAVKAEFKKNRISTTSEIKPSKVKQYLKKLGYSMYYENIFTIANMISGIPTLKLSRELEKRFKDMFYEIQEPFFRHKPPKRKNFLSYNYVLYKFAELLGEDDLLQYFPLLKCSKNLHNQDVIWKKICADLQWQYIETV
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Putative transcription factor B663R.
What is the protein family that this protein belongs to?
Belongs to the nucleo-cytoplasmic large DNA viruses (NCLDVs) VLTF-3 family.
Protein: PG44_MYCTU
Sequence: MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAGGSAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGGAGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGDGGAGGTAGGRLFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGTGATLIGLGAGGGGGIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGGGLFSIGVGGDGGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSGGILFGANGANGPS
What are the official names of this protein?
Uncharacterized PE-PGRS family protein PE_PGRS44.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
Protein: SELO_TRIV2
Sequence: MTLAETFNTENHPNPLITLNYEPALESLGNDYYDEVTAAEFPQLTLRWRNDAILPRLGLDPQTVTDEDFITAFGLFQGRKPLLALRYHGYQFGEYNPNLGDGRGFLYGQVRGTDGELYDFGTKGSGRTPYSRGGDGMLTLKGGVREVLAAEALHQLGVRTSRCLTMIETGLGLWRGDEPSPTRSSVMVRMNKSHIRFGTFERLHYFQRSDLIKKLLDHVIEHYYQHLTHESDKYALFYAELVKRVAELVAQWMAAGFCHAVLNTDNMSITGESFDYGPYAFIPTYNPYFTAAYFDYYGRYCYIQQPSICQWNLEMLQVPLRAVIDKADMEAGLAKFNEYCHAEYHSLMLKKLGFEQLTTPEAEELLSLTLKFLQESQVGYHQFFYEMARTFSVKWRDEPGLVLSGSDIVPPSGTDANFDNWCVLYHKILNNFDYEQVKIIAQNLTYYNPKTSLLRPTIEEAWEPIVQEDNWQPFYDLVKSIQSRG
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: GLYA_NITOC
Sequence: MYSKEMRIASYDEELETALTNEARRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGGCEYVDVAERLAIERAKILFEADYANVQPHSGSQANAAACLALLAPGDTLMGLSLAHGGHLTHGAKVNFSGQIFNAVQFGVNADTGLIDYDEVEQLAKAHRPKLIIAGFTAYSRIVDWQRFRAIADGVGAYLLADIAHLAGMIAAGIYPNPVQIADVTTSTTHKTLRGPRSGLILAKANPEIEKKLNSKVFPGIQGGPLMHVVAAKAVAFKEAMEPAFKDYQRQVIRNAQAMAEAIQSRGYKIVSGGTDSHLFLVDLVAKGLTGKAADAALGRANITVNKNTVPNDPQSPFVTSGIRIGSPAMTTRGFKEAEICELAGWVCDVLDDIENETVIADTKEKVLALCARFPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGPRT_STAAM
Sequence: MHNDLKEVLLTEEDIQNICKELGAQLTKDYQGKPLVCVGILKGSAMFMSDLIKRIDTHLSIDFMDVSSYHGGTESTGEVQIIKDLGSSIENKDVLIIEDILETGTTLKSITELLQSRKVNSLEIVTLLDKPNRRKADIEAKYVGKKIPDEFVVGYGLDYRELYRNLPYIGTLKPEVYSN
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RICR_MYCTU
Sequence: MTAAHGYTQQKDNYAKRLRRVEGQVRGIARMIEEDKYCIDVLTQISAVTSALRSVALNLLDEHLSHCVTRAVAEGGPGADGKLAEASAAIARLVRS
What is the function of this protein?
Under low copper conditions, represses the expression of lpqS, Rv2963, mymT, socA, socB, mmcO and its own expression.  In the presence of copper, RicR dissociates from DNA, leading to the expression of the target genes.  Members of the RicR regulon are important for copper resistance during infections and full virulence in a mouse model of infection.
What are the official names of this protein?
Copper-sensing transcriptional repressor RicR, Regulated in copper repressor.
What is the protein family that this protein belongs to?
Belongs to the CsoR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_THEP3
Sequence: MVKVKICGLRRKEDIEYANELKPDYVGFVFAKSKRQIEVEQALDLISLLDKEIKTVGVFVNEPVENALKIAQTLNLDVLQFHGDETQDYIDNFKNFTVWKAIRIKDKEDLEKTKQFKVNSFVFDTLTKNEYGGTGKTFNWKVLKGMELNVPIILAGGLNENNVEEAIKIVDPYAVDVSSGVETEGYKDFKKLKSFIEKVRGIR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: GUEN_SYLGU
Sequence: VIDDLKKVAKKVRRELLCKKHHKKLN
What is the function of this protein?
Antimicrobial peptide.  Active against the Gram-positive bacteria S. aureus FDA209P (MIC=35. 5 ug/ml) and B. subtilis ATCC 6633 (MIC>64 ug/ml), but not active against the Gram-negative bacterium E. coli or the fungus C. albicans.
What are the official names of this protein?
Guentherin, AMP-3.
What are the subcellular locations of this protein?
Secreted.
Protein: RL33_PSYIN
Sequence: MRDKIRLNSSAGTGHFYTTDKNKKTMPEKFEIKKFDPVVRKHVMYKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RNS7_PYRPY
Sequence: MGITGMIYIVTMVFSLIVLILSSSTVGYDYFQFTQQYQPAVCNSKPTPCKDPPDKLFTVHGLWPSNLNGPHPENCTNATVNPHRIKNIQAQLKIIWPNVLDRTNHVGFWNKQWIKHGSCGYPAIMNDTHYFQTVINMYITQKQNVSEILSKAKIEPLGIQRPLVHIENAIRNSTNNKKPKFKCQKNSGVTELVEVGLCSDGSLTQFRNCPHPPPGSPYLCPADVKY
What is the function of this protein?
Self-incompatibility (SI) is the inherited ability of a flowering plant to prevent self-fertilization by discriminating between self and non-self pollen during pollination.  In many species, self-incompatibility is controlled by the single, multiallelic locus S.
What are the official names of this protein?
Ribonuclease S-7, S7-RNase.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: HIS3_METPP
Sequence: MTWLDDIRWDRDGLLPVIAQEAATGDVLMFAWMNREALARTAELGEAVYWSRSRGRLWHKGEESGHIQKVRDMRLDCDNDVLLLKVEQLGHEPSIACHTGRHSCFYQRYESGAWHAVELVLKDPEHIYR
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_SALCH
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFRPYNGFTLDFTIDFNHPAIDSSSQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDDAELPLAFKAPSTVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RL7_BIFAA
Sequence: MAKYTNDELLEAFGEMTLVELSEFVKAFEEKFDVEAAAPVAAVAAAPAAGAAAEEEKDEFDVILSAVGDKKIQVIKAVRAITNLGLAEAKALVDGAPKAVLEKAKKEDAEKAKSQLEEAGATVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: EPHA5_HUMAN
Sequence: MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5.  Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways.  Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis.  In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).
What are the official names of this protein?
Ephrin type-A receptor 5, Brain-specific kinase, EPH homology kinase 1, EHK-1, EPH-like kinase 7, EK7, hEK7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite.
Protein: ARNA_ECOL6
Sequence: MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPRGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKSASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACAARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFMNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHYFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNARRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: LEP4_LEGPN
Sequence: MINALIINYPWFMYLVVGLFSLAVGSLLNVIIYRLPIILQEEWKEQCCELFHFEQRKEKIKLNLFLPRSFCPHCKAMVKAWQNIPLLAILVLRGRCYQCDSPFSIRYPFVETLTTVLSLYASWHFGFTIQLLFALLAIWILISLVFIDLDHQLLPDSLTLGLLWIGLIANTQNVFVSLDVAVLSCAGAYLALWLFINLFYLMTCKVCMGHGDFKLFAAFGAWLGWMYLPIILLISSITGAIIGLIYLKINGKSRDTAIPFGPFLCISGLIAMFWGDSIINWYIGYWM
What is the function of this protein?
Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.
What are the official names of this protein?
Prepilin leader peptidase/N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SWT7A_ORYSJ
Sequence: MVSPDMIRNVVGIVGNVISFGLFLSPVPTFWQIIKNKNKNKKKMEVVLAAEALFMVSPDMIRNVVGIVGNVISFGLFLSPVPTFWQIIKNKNKNKKKMEVVLAAEALFMAAVALGVLLGVHTHQRRSLIVGILCVIFDTIMYSSPLTVMSQVVKTKSVEYMPLLLSVVSFLNGLYWTSYTLIRFDIFITIPNGLGVLFAAVQLILYVIYYRTTPKKQNKNLELPTVTPVAKDTSVGPISKDNDLNGSTASHVTIDITIQP
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET7a, OsSWEET7a.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEXT_BACLI
Sequence: AYTVTLYLQG
What are the official names of this protein?
Dextranase, Alpha-1,6-glucan-6-glucanohydrolase.
Protein: LEUC_SYNJA
Sequence: MSERTLFDKVWDAHTVRVLPSGQTQLFIGLHLIHEVTSPQAFAMLRERNLPVLFPERTVATVDHIIPTDNRTRPFADPLAEEMIQELERNCRQYRIRFYNSGSGQQGIVHVIAPEQGLTQPGMTIACGDSHTSTHGAFGAIAFGIGTSQVRDVLATQTLALSKLKVRRIEVHGRLGPGVYAKDVILHIIRKLGVKGGVGYAYEYGGSTIEAMSMEERMTLCNMSIEGGARCGYVNPDAVTFEYLKGREFAPQGSDWEEAVAWWQSLASGPDAVYDDVVVFQAAEIAPTVTWGITPGQSIGVDERIPAPEELPESERELAKEAYAYMGLRPGDPIVGTPVDVCFIGSCTNGRLSDLREAAKIAKGQRVAPGVKAFVVPGSERVKQEAEREGLREIFEAAGFEWRDPGCSMCLAMNPDRLVGRQISASSSNRNFKGRQGSPSGRTLLMSPAMVAAAAVSGKVVDVRELL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: HUTG_STAEQ
Sequence: MYQLAQSNLWTGRLDSETDPTQFRHFQTVKFGDLSQLDFSDEHKGVGLLGYAIDKGVELNKGRVGAKEGPNAIKRAFAGLPDLNQCEEIIDYGNVEHNHELLIDTQREFADLAAKSIKRHKQTFLLGGGHDIAYAQYLATRKVYPESSIGVINIDAHFDTRDEGYSTSGTSFRQILEEDDNADYLVLGISQGGNTQALFNYAKEKDIQFVYADELLHQVSPPIKDMIERFIHNHDTVMFTICMDVVDSAFAPGVSAPAVLGIYPHTVFELAKRVIPSEKVKSISIAEMNPTYDSDQRTAKLVANLVHHCLI
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: GLYAL_MOUSE
Sequence: MLHLRSSQMLQMLESSLRKYLPESLKVYGTVFHMNQGNPFKLKALVDKWPDFNTVVVRPREQEMGDDLDQHTNTYQIYSKDPKHCLEFLGTPDVINWKQHLQIQSSQSNLNEAIMDLAAGKMVKVKRTQCILYMMPETAKKLVPSLLEDKEYLDHQSGRPRAIDQEMFKLSTLDVTHAPLVDKFWQFGGNERSQRFIGRCIQIFPSSCLLGPEGTPVSWALMDQTGEIRMAGTVPDYRAQGLISHIIYAQTLAMDKRGYPVYNHTEQTNKVIQKMSHTLHHVPMPCDWNQWYCAPL
What is the function of this protein?
Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine.  Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity).
What are the official names of this protein?
Glycine N-acyltransferase-like protein, Acyl-CoA:glycine N-acyltransferase-like, AAc-like.
What is the protein family that this protein belongs to?
Belongs to the glycine N-acyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LRGB_STAAW
Sequence: MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COBT_VIBC1
Sequence: MDRSFASEIQARIDNKTKPLGALGLLEKVALELALIQSQDKLQSVETIEIRKPTMLVFAGDHGIAKEGVSIAPSAVTQQMVANFLAGGAAINCFCDLNQIDFKVVDCGMLSPIDTLVPDFKHHPNLIERRLGNGTANFAKQTAMSLEQVALGLEYGAKVAQQAILNGSNLLMFGEMGIGNTSSASALLTALSLLEVDHCVGYGTGITQEQLNRKIKLVAQGVNRCHDLDTKGALAQVGGFEIVQMVGAFLEAKRHKTPVLVDGFIVSVAAYVATLLDEETRDYMLFAHNSEENGHKFVLECLQAEPLLDLGLRLGEGTGAALALPLVKAAAQFYNNMASFESAGVTV
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: KDPC_KINRD
Sequence: MSLALTNLLRQARTGLLLLLVATAGLGLVYPLAVFAVGRLVPARADGQVVAVDGQPVGSRLIGQEFPGEQWFQPRPSAAGDGYDPTASGASNLGPESTDLLKAVEERRAAVAAADGTAPVDVAPDALTASGSGLDPHVSPENARRQVARVAAARGLSEQRVAALVAEHTRGRALGFLGEPTVNVLELNLALRSAAP
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CFM3B_ARATH
Sequence: MAINSSHHFCPMTTTTTTSAKFVDSLGSSFCKFHGTSSSISLRSYRFGFSFMKNVKRLSCEGSSSSSSSRNENWNRTQKQNQFRPSKVVLNRRKDERFSDLGVISGENSSRSGDVGGGSGSSSTMEKIVEKLKKYGFVDEDQFQDKEVEQERRIEKSSVEERFYVEERRGGFSEESPFGVYGGNDEVKFPWEKVSSMEKKELVNGEWTAKKESRYSLAEMTLSEFELNRLRNVMFRTKSKMRVTGAGVTQAVVDAIQEKWKGSEIVRLKIEGSSALNMRRMHEILERKTGGLVIWRSGTSIALYNYKGGSNRDGSGNMNKQVYRRAERLPSSLPTSTVDQSVQLVNLPQLEKEPTVVGNKDRTSPQEVEYEDEINELLEGLGPRYTDWQGGYPLPVDADLLPGIVPGYEPPFRALPYGVRSTLGTKEATSLRRIATVLPPHFALGRSRQLQGLATAMVKLWQKSLIAKVALKRGVQLTTSERMAEDIKRLTGGMLLSRNKDFLVFYRGKSFLSLEVGEALMEKEMLVRTLQDEEEQARLRASSALVVPSIKANQQLARTLQDKEEQARPSALVLPSTKANQNLVSAGTLGETLDATGKWGKNLDNDDHVEEMKQEVEKVRSAKLVRKLERKLAFAEKKLLKAERALAKVEESLKPAEQRTDLEGITEEERFMFQKLGLKMKAFLLLGRRGVFDGTVENMHLHWKYRELIKILVKAKTLEGAQKVAMALEAESGGILVSVDKISKGYAVIVYRGKDYKRPTTLRPKNLLTKRKALARSLELQKREALIKHIEAIQTRSEQLRAEIEQVELVKDKGDETLYDKLDMAYSSDEETEETDGEEDDVYLDTYEDEGEDDEEGGIQANGSLSETDVEFGSDESDTDFGDNSASSTTPETTFVELQNEELDVQP
What is the function of this protein?
Binds specific group II introns in chloroplasts and facilitates their splicing (PubMed:18799595, PubMed:32143506).  Exhibits non-specific action during plastid rRNA biogenesis; RFC3 prevents unaccurate splicing to improve the accuracy of plastid rRNA processing (PubMed:32143506).  Acts on subgroup IIB introns (PubMed:18799595).  The substrates of the subgroup IIB also require the CRM domain proteins CAF1 or CAF2, with a simultaneous binding of CFM3B and CAF1 or CAF2 (PubMed:18799595).  Required for seed development (PubMed:18799595).
What are the official names of this protein?
CRM-domain containing factor CFM3B, chloroplastic, Protein CRM FAMILY MEMBER 3B, AtCFM3b, Protein SUPPRESSOR OF RFC THREE 2.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid. Note=Localized to root plastids.
Protein: PSBI_NASOF
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.