PharMolix/UniProtQA huggingface dataset:
Protein: KREM2_MOUSE
Sequence: MGTPHLQGFLLLFPLLLRLHGASAGSLHSPGLSECFQVNGADYRGHQNYTGPRGAGRPCLFWDQTQQHSYSSASDPQGRWGLGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPTCHMPGYLGCFVDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRPAPATDCDQICFGHPGQLCGGDGRLGIYEVSVGSCQGNWSAPQGVIYSPDFPDEYGPDRNCSWVLGQLGAVLELTFRLFELADSRDRLELRDVSSGNLLRAFDGAHPPPPGPLRLRTAALLLTFRSDARGHAQGFALTYRGLQDTVEGRASPEDSTESLAGDPDGANASCSPKPGAAQASIGARVFSTVTAFSVLLLLLLSLLRLLRRRSCLLAPGKGSLAMGPSRGPGRSWAVWYRRPRGVALPCPPGDSQAEGPAAGYRPLSASSQSSLRSLVSAL
What is the function of this protein?
Receptor for Dickkopf proteins.  Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6 (PubMed:12050670).  Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation (PubMed:18505822).
What are the official names of this protein?
Kremen protein 2, Dickkopf receptor 2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SYR_BURPS
Sequence: MLPAQKHTLETLLENSVKQVVQASKGDADAAFVLPAIALERPKVAAHGDVACNVALQLAKPLGANPRQLAEQIVAALTAQPEAAGLVDAAEIAGPGFINLRLTPASKQAVIGAVLAQGRAFGASERDHGKRVLLEFVSANPTGPLHVGHGRQAALGDALANVLASQGYAVHREFYYNDAGVQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDYLNGETVAASDGEPVTGKRDVEDLEAIRKFAVTYLRREQDMDLKAFGVKFDQYYLESSLYTEGRVEKTVDALIAAGMTYEQEGALWLRTTDEGDDKDRVMRKTDGTYTYFVPDVAYHVTKWERGFTKVINIQGSDHHGTIARVRAGLQGLHIGIPKGYPDYVLHKMVTVMRDGQEVKISKRAGSYVTVRDLIEWSGGATPGSEGSPELLDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARICSVINEWKSRYGATDALLPGADLSPLDSKQAMALMQKLAEYPDVLAHAAGELAPHAVAFYLRELASEFHSFYNAERVLVDEQAPRTARVALLAATRQVLENGLAMLGVSAPSKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN103_RAT
Sequence: MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWNNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLRLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRSNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVDSDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGAQSEEEMSESSQDTENDSDSDNTDTFSSSKDVFEDKQNVHSSPGRTSRCDTEACSCANKCVSSPCERKRRSYGSHNTKEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQQQPLSNDAPS
What is the function of this protein?
Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF103, Protein ADRG34, RING finger protein 103, RING-type E3 ubiquitin transferase RNF103, Zinc finger protein 103, Zfp-103.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HISX_THET8
Sequence: MIYAAEEVRARFARRGLSFDPTVEEIVRGILEAVREEGDEALDRFSRDLDGYPVEEVPKRAWREAYEDLDEDLRDALETARERIEAFYREEARGGFLRAEGGGVLAQLVRPLERVGVYVPGGSAPLLSTLLMTVVPAKVAGVREVIVASPPKVHPGVLAAAWVAGADRLFAMGGAQAIAALAYGTGRVPRVDKIVGPGNRYVVAAKRLVYGTVGIDGLAGPTETMIIADGSASPRLLAADLLAQAEHGPDSEPWLLSPDRALLERVEAELSWQLQDLPRAEVARQALEKGGLVLTKDLEEAFALANLYAPEHLSLALSDPLPWLEKVQNAGGVFLGEGSPEALGDYIAGPSHVMPTSGTARFQGGLAVRDFLKVIPVVGLSEGAARELAKKGALLARAEGLEGHARSLDLRR
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: PE2R4_RAT
Sequence: MSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMLRQFMRRTSLGTEQHHAAAAAAVASVACRGHAAASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQLYQPSVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRDGSAQHCSESRRTSSAMSGHSRSFLSRELREISSTSHTLLYLPDLTESSLGGKNLLPGTHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSQREEPASKGNSLQVTFPSETLKLSEKCI
What is the function of this protein?
Receptor for prostaglandin E2 (PGE2).  The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase.  Has a relaxing effect on smooth muscle.  May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
What are the official names of this protein?
Prostaglandin E2 receptor EP4 subtype, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostanoid EP4 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MOCOS_BOTFB
Sequence: MEEYNKAVEEFRKHEYPMLKDAVYLDHAGTTLYSKSLMERYMGDMMSNLYGNPHSASTSSQLSTSRIENTRLNVLQFFNADPEDFDVVFVANATAGIKLVMDAFRCQEDGFLYGYHQDSHTSLVGVREDAVSSRCLDDDAVECWLSGSEALVRNEHNSEIGLFAYPAQSNLDGRRLPLSWPERVRNLSYEAQANTYTLLDASALVSTSPLDLSDVSKAPDFTVLSFYKIFGFPDLGALIVRKDSGAILQTRKYFGGGTVEVVVCLKEQWHAPKGQSLHENLEDGTLPFHNIMALEAAIDVHKSLYGSMECIANHTTFLARKLYEGLKSLQHANSEPACIIYSPGFSETSSNVQGPTIAFNVKNSFGAWVTNVEFERLASIKNYHIRTGGLCNPGGVASALELQPWETRRNFSAGLRCGGETDIYAGKITGVIRVSLGAMSTMSDVDSFLSFVNEFFVDHTVVSADEDGESQKSVDMYVESLTIYPIKSCGGFEIPKETAWEVRPEGLAWDREWCLIHQGTGQALSQKRYPRMALIKPTIDFDLGLLKLRYQGSTFPTLVDEISVSLSSDPSSYKNPNNIHSLSSRVCGDAIAAQTYFDHEINDFFSKILEAPCVLARFPAGGSGPSLRHAKAHMQKHQGPKRSAAIEKSSAHSFHDPPTPPDSDSENRKRPILLSNESPILAINRSSINMLNEEIAKSGGKLASASVFRGNIVLASTELTDSHHPYSEDHWSTLQIGSETYQMLGSCRRCHMICVDQDTAEKNEEPFVTLAKTRRFESKVFFGSHMCHVPSFSRHKKHQFPVIKVGDKVSIGL
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase, MCS, MOS, MoCo sulfurase, Molybdenum cofactor sulfurtransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Protein: Y193_ATV
Sequence: MSARQPQNNNQQNNNSILQALQQVQQQNRPIVANIARIDPYMANMAYKMYNEIDVSINESVSTIDITNKMLRIAKGMIRSIEQGHAKMSATPFTLKESFKSLVMELLDVAYTDINTFMTQKYLELQENLTNNDLKKIHELNKTVMEYGLIYINAIHFVLLDTQGFLNEKLPTQLISPVDSARLLGHFHLKHKT
What are the official names of this protein?
Uncharacterized protein ORF193.
Protein: PYRE_YERPE
Sequence: MKAYQREFIEFALNKQVLKFGEFTLKSGRISPYFFNAGLFNTGLDLAKLGRFYAAALMDCGVEFDLLFGPAYKGIPIATTTAVALAEHHERDVPYCFNRKEAKTHGEGGNLVGSPLQGRVMLVDDVITAGTAIRESMEIINAQGATLAGVMISLDRQERGRGEISAIQEVERDYHCKVIAIVTLNDVIRYLEDKPEMAEHLVAVRQYREQYGVTL
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: IOVO_BALPA
Sequence: TAMVDCSDYPKPACTLEYMPFCGSDSKTYSNKCNFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: LDL3_ARATH
Sequence: MDGKEKKSGSKRGSKVFQFDDDADDDEPIGSLLEIMKHKSSKKDKVETESTGKQRQKQVVEKKLSALGKDSEDMDDTLASFRKRLKGNKKGVESGTSRVRNHEGVDTVTNSNLKPIEEANKNEVQSVLLRENGASNSIQKCASETGTLLHKFSGKDKAASPSHEKVETVSSEKEADVFHQITKEESEIPMSEKAVELSRVSVPMPDVHGEVNCTIAPDKHIHLGEPTSESGYYREKNLVMCDCGTQFNFEDRSFESNTQVTLCQKCKYSSHHNASNGGGIQVNTLEDGTAQASPVSIIPCEDENFRGDAISLPNSGKPSTLQRPERIAKKRKLGNMVYEGDVKWENEQGFLDCQSDKSFKGSDKCGFVPSISKEIEIGRAAAVTAGLKAQSVSPIEKIILKEVLKRKGSNQEYLVCRNSILGLWSKNVSRILPVTECGVTGGPSESELPSASLIREVYKFLDQRGYINAGISSVNGKAASSTNQDYDLLQGRQLEESSMASVADSEEGVAFILGQVKAVESTSEGKKCALQNDERDLVGCATSEMLESISKKCEASIIDDNKRSVSMNALQDSTASNVEKHPETFSVAKPALSSTLSSAHSNQMRGRDCVPCEVIDEKKVIVIGAGPAGLTAARHLQRQGFSVTVLEARSRVGGRVFTDRSSLSVPVDLGASIITGIEADVPSERMPDPSVLVCNQLGLELSVLHGFCPLYDTVTGKKVPAELDDALQAEFNSLIDDVDLLVEEIGKERANKMSLEDGLEYGLQRLRMPHDKVNIDKFGLLNSSSKTGIRGPFMQDESWKDDFLNPLERRVMNWHFAHTEYGCAAVLKEVSLPHWNQDEFYGGFGGPHAMIKGGYSRVVESLAEGLDIHLNKIVSDVSYVSDVSAMDNSKHKVRVSTSNGCEYLGDAVLVTVPLGCLKAETIKFSPPLPDWKYASIKQLGFGVLNKVVLEFPTVFWDDSVDYFGATAEETDLRGECFMFWNVKKTVGAPVLIALVVGKAAFEYTNKSKSEHVNHAMMVLRKLFGGDLVPDPVASVVTDWGTDPYSYGAYSYVAIGASGEDYDVLGRPVQNCLFFAGEATCKEHPDTVGGAMMTGVREAVRIIDILRSGNDYTAEIETLEKAQRKSVPVRDEVRDLIKRLEVVELSNVLARQSLLRNMFFSAKTTVGRLHLAKELLNLPGETLKSFAGTKEGLAVLNSWILDSMGKNGTQLLRHCVHILVRVTSDLFALRLSGIGKTVKEKVCAHTSRDIRAIASQLVNVWLDLYRKEKANSGKKSLRQANTTNTSRIRRKLNSPDTDSKGKLSNGNDVKTDEEFEDNQLPMSEEEKAVFAEAEAARAAAEAAAKAFSEAYHNTSLQLPKIPSFHKFARREQYAKMDESDFRKKFPGNVLGRQDCMSEIDSRNCKVRDWYDFPASCLDLDSARIPVDNYSQPSHSNELVSHSKFRECSGESVAADTSFLTGAWVDTGGSSDGFKDSQAIDRWQSQAAAADPEFFNRTLHIKDEEDSIACSTGPPSWKHDQRANECSVSQVTVNKEPHKNHIRSADRLKQGVVDFVASLLMAPYRAKKIDRDVYKSIMKKTATKVMQHTTDVEKAMAVTQFLDSKRKNKIRDFVDKQVDKYMVIPQVPKP
What is the function of this protein?
Probable histone demethylase that reduces the levels of histone H3 'Lys-4' methylation in chromatin.
What are the official names of this protein?
Lysine-specific histone demethylase 1 homolog 3, Flavin-containing amine oxidase domain-containing protein 3, Protein LSD1-like 3.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: AN_HHV6U
Sequence: MDLDQISETLSSVAEEEPLTMFLLDKLYAIREKIKQVPFSIVRLCHVYCMLIKYNASNNNCILGRKLIEEMQQFLCGTRVDGSEDISMDLSELCKLYDYCPLLCSALCRAPCVSVNKLFKIVERETRGQSENPLWHALRKYTVTATKLYDIYTTRCFLEYKGQQFFGEAVIYGAKHERVIRHLVATFYVKREVKETLGLLLDPSSGVFGASLDACFGISFNEDGFLMVKEKALIFEIKFKYKYLRDKEDHFVSELLKNPTEKSFSDFILSHPVPVIEFRERGKIPSSREYLMTYDFQYRPQRKLRTCPTPAILAPHIKQLLCLNETQKSTVIVFDCKSDLCEQKLSVFQKAVFTVNVFVNPKHRYFFQSLLQQYVMTQFYINDHNNPEYIESTEVPSVHIVTAFFRRRTEEERSLHLVIDETEYIEEEIPLALIVTPVAPNPEFTCCVITDICNLWENNICKQTSLQVWAQSAVNQYLAACVRKPKTP
What is the function of this protein?
Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules.  Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate.  Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides.  Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity.
What are the official names of this protein?
Alkaline nuclease.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae alkaline nuclease family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: YOQS_BACSU
Sequence: MYRKIFDMVNGSEEQSKITDWLYKLMIEDENSLYKIDIKVSKRRISEQGDIYREEGEYIENADLQTLPIGTKSFVQNGCWKGEIVSNEKKHLYMPQIGEMREIKVGSTGLNIEIE
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YoqS.
Protein: DAPA_BARQU
Sequence: MLKGAVTALITPFDDNGAIDEKAFCNFVEWQITQGINGVSPVGTTGESPTLSHEERKQVVELCVEQVAKRVPVVAGAGSNSTSEAVELAQHAEKAGADAILVVTPYYNKPNQKGLYTHFSSIAKAISIPVIIYNIPGRSVIDMAVETMRDLCQDFKNIIGVKDATSKIGRVSEQREKCGKDFIQLSGDDCIALGFNAHGGVGCISVSSNVAPKLCAELHAACFRGDYETALKLNDLLMPLNRAVFIEPSPAGIKYAAAKLGLCGSLVRSPIVPLAETTKKIIDAALHHAGLLKE
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PARL1
Sequence: MATGAEQTGGGFPVDPLHQFVVQPLIPLNIGGLDASFTNASLWMVVTVVAIGLFMTLGMRSGAMVPGRMQSVVESFYTFIANMVRDNAGHDAMRFFPFIFSLFMFIFFANMIGMFPYAFTVTSHIVVTFALAIVVFLGVTLTGFVLHGPRFLKVFVPSGVPMALLPLVVAIEIISYFSRPISHSVRLFANMLAGHIMLKVFAGFVLTFMTMGVVGWAGMILPLFMIVALTALEFLVAALQAYVFTILTCMYLHDALHPGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HFLX_NITMS
Sequence: MKSAILITYDKEDVINEAKGLCDAAGFQVVHTIKQKFLKRPKYGISGGILERLEEISEKIRPDVIVFDEVLKPSQNYNLAAALHREILDREALILEIFESRASSAESKLQVKLAQLRYEMARAKEKVRLSSMGEQPGFMGIGKFEVDVYYNDIKHRMNTVRSKLEKAGKQRELHRQGRKRMGFKTISLAGYTSAGKTTLFNMMTGETRDQSSELFTTLSTTTRRVSINQEPFLISDTVGFISKLPAYMIDAFKSTLEELGHTDIIIVVIDIGDSIFELKKKFSSCMRTLSELGVEKDRMVYALNKSDLLEHSEIEEKIETLNLVDNKKWIPVSAKTGKNVKQLKELIGDILESHNSHKFGKKIGVEETFGN
What is the function of this protein?
GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
What are the official names of this protein?
GTPase HflX, GTP-binding protein HflX.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=May associate with membranes.
Protein: PSAC_SYNSC
Sequence: MSHAVKIYDTCIGCTQCVRACPLDVLEMVPWDGCKAGQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGDETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GHRA_ECO57
Sequence: MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALAWHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLKPSVPLFRLEDTGMGEQMQEYAVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRFPLRCWSRTRKSWPGVQSFAGWEELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITRPAEAVEYISRTIAQLEKGERVCGQVDRARGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEP7_ARTOC
Sequence: MRFSIVLSSIAALSSVAAAERVCGAIPHRTFAKESKAAIEAATAAGLTTKANITVETYFHVITAGSKGEINNYGPAGIGFKLMDVSRTDNAKWASGGDETGMKKSLRKGGYSALNVYFAPNLEGGLLGFCYFPKANPSANDKLVDGCVILSGSVPGGEAAPYNEGKTTTHEVGHYMGLYHVFNEEQGNCQKDGDMVADTPVQGTKTSGCPQGKDSCPGQGVDSIHNYMDYSDEYVLLSPVYDSWHQTNHRHFSPCMNQFTPGQISRMQMMWQQFRAGK
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Plays a pivotal role as a pathogenicity determinant during infections and contributes to the ability of the pathogen to persist within the mammalian host (By similarity).
What are the official names of this protein?
Extracellular metalloprotease MCYG_03238.
What is the protein family that this protein belongs to?
Belongs to the peptidase M43B family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPA2_CAEBR
Sequence: MLILFLLRTHSCNFQNFESFLGAGECGKSTVLKQMRLLTSKTYTADELEAQAKLVFTNIVIEMDHIVKAMPSAHFNFTDPMREHDVHMLTLYIKDMQHKSFHADAAEHVAKLWKDPVIKRLYAERRERNIRDIGDNTEYFFENLDRIAKPDYSPNSMDTLLLRTKTTGIVEVQFEIKKVKFRVFDVGGQRSERKKWIHCFEDVNAIIFIAALSEYNEVLFEDETTNRMIESMRLFESICNSRWFHNTNIILFLNKKDLFEDKIKKENITKAFPEYRGAQNYEETVAFIKQKFEALSNNPKKTFYVHETCATDTNQVQKILDSVISMIIQSNLHKSGLY
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  Involved in behavioral responses to P. aeruginosa by controlling the expression of daf-7, a member of the TGF-beta family, in ASJ sensory neurons.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-2 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
Protein: TRMFO_LACJO
Sequence: MVKNVTVIGGGLAGSEAAWQLAKRGIEVDLYEMRPKKNTPAHETANFAELVCTNSMRSNQLSNAVGLLKEEMRQLDSLIMKAADETAVPAGGALAVDRDKFSAVVTKTLKDLPNVHVHEEEITEIPKDGITIIATGPLTSDTLAEQIKEFCGTDSLHFFDAAAPIVAASSINRDIVYKKSRYDKGEAAYLNCPMTKEEFYNFYKNLVGAETATLHGFEDKNVFEGCMPIEVMAKRGEKTMLFGPLKPVGLEDPKTGKTPYAVVQLRQDNAASTMYNIVGFQTHLKYGEQKRVFSMIPGLENAKFVRYGKMHRNTYIASPEVLNANYEARKQTGLFFAGQMTGVEGYVESAGSGLVAGINAAREALGEETLFFPKSTALGSMANYITTTSAKHFQPMNASYALLPKLDYKVRNKQERHLEISKRALKDLEAFKEEKKLD
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_BURM1
Sequence: MKKSARRQSRELATQGLYQWLLSNASSGEIDAQLRGALGYDKADKALLDAILHGVIREHATLVDALTPSLDRPIDQLSPVERAVLLIATFELTHHIETPYRVVINEAVELAKTFGGSDGYKYVNGVLDKLAAKLRPAETQARRNG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: GLN12_ARATH
Sequence: MSLLADLVNLDISDNSEKIIAEYIWVGGSGMDMRSKARTLPGPVTDPSKLPKWNYDGSSTGQAPGQDSEVILYPQAIFKDPFRRGNNILVMCDAYTPAGEPIPTNKRHAAAEIFANPDVIAEVPWYGIEQEYTLLQKDVNWPLGWPIGGFPGPQGPYYCSIGADKSFGRDIVDAHYKASLYAGINISGINGEVMPGQWEFQVGPSVGISAADEIWIARYILERITEIAGVVVSFDPKPIPGDWNGAGAHTNYSTKSMREEGGYEIIKKAIEKLGLRHKEHISAYGEGNERRLTGHHETADINTFLWGVANRGASIRVGRDTEKEGKGYFEDRRPASNMDPYVVTSMIAETTLLWNP
What is the function of this protein?
Low-affinity glutamine synthetase.  May contribute to the homeostatic control of glutamine synthesis in roots.
What are the official names of this protein?
Glutamine synthetase cytosolic isozyme 1-2, Glutamate--ammonia ligase GLN1;2, GLN1;2.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_THET8
Sequence: MFHGKHPGGLSERGRALLLEGGKALGLDLKPHLEAFSRLYALLQEASGKVNLTALRGEEEVVVKHFLDSLTLLRLPLWQGPLRVLDLGTGAGFPGLPLKIVRPELELVLVDATRKKVAFVERAIEVLGLKGARALWGRAEVLAREAGHREAYARAVARAVAPLCVLSELLLPFLEVGGAAVAMKGPRVEEELAPLPPALERLGGRLGEVLALQLPLSGEARHLVVLEKTAPTPPAYPRRPGVPERHPLC
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.  Shows a marked preference for deproteinized 16S rRNA as substrate and is completely inactive with native 30S subunits as substrate.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase, Glucose-inhibited division protein B.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKT5_ARATH
Sequence: MGIEKRKKMVWFWPEKHEGGVIKEAEDVAAEHISREGTMSHYSFSKGLLPPLGVGATARSSRHIKLRCFIVSPFDPRYRAWDWFLVILVLYTAWASPFEFGFLQTPRAPLSILDNVVNGFFAVDIVLTFFVAFLDKATYLLVDDPKRIAWRYTSTWLIFDVVSTVPYELFGSLLHNTIQGYGIFSMLRLWRLHRVSKCFARLEKDRKYNYFWIRCTKLLLVSLFVVHCGACFCYSIAAHYPDPSMTFMALAEANWKQKSLLIRYVTAMYWSITTFSTTGYGDIHGNNAEERAFILFYMIFNLGLLAYIIGNMTNLVVHVTSRTRNFRDTIQAASAFAQRNNLPLGLQEQMVAHLSLRYRTDSEGLQQQEIIDSLPKAIRSSISHYLFYEVVDKTYLFHGISNDLLFQLVSEMKAEYFPPKEDVILRNEAPSDFYIMVTGAVDIIARVNGVDQVVGEAQTGHVFGEVGVLCYRPQLFTVRTKRLSQLLRLNRTAFLNLVQANVGDGAIIMNNLLQHLKDSTDPVMKGILAETELMLAQGKMDLPLSLCFAAARGDDLLLHQLLKRGSNPNETDKNGRTALHIAASKGSQYCVVLLLEHGADPNIRDSEGSVPLWEAIIGRHEENAKLLSENGATLSFDTVGYFSCLAVGQNNLNALKDIVKYGGDISLSDVNGTTALHRAVSEGNLEIVQFLLEKGADMDKPDVYGWTARALAEHQGHEDIKALFYNQRPVERKTILVSGTPEIKPLMKHSSEPVMTHHHSREAMPPLARAVSQRRKLSNFKNSLFGIMSAAKTGDEGGASTRTGISEGVGGVYPARVTISGEASSSGKVVKLPDSLEELIEIGEKKLGFVATKILSREGAEIDDIRIIRDGDFLLLLKVS
What is the function of this protein?
Probable potassium channel.  May interact with the cytoskeleton or with regulatory proteins (By similarity).
What are the official names of this protein?
Probable potassium channel AKT5.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NS1_I51A0
Sequence: MDPNTVSSFQVDCFLWHVRKQVADQELGDAPFLDRLRRDQKSLRGRGSTLGLNIETATRVGKQIVERILKEESDEALKMTMASAPASRYLTDMTIEEMSRDWFMLMPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTNEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWRSSNENGRPPLTPKQKRKMARTIRSEVRRNKMAD
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: MURI_CERS5
Sequence: MAVGVFDSGLGGLTVLDAVQRRLPEVPFVYFGDNAHAPYGVRDADDIFALTCAATERLWAEGCDLVILACNTASAAALKRMQESWIPRDKRVLGVFVPLIEALTERQWGDNSPPREVAVKHVALFATPATVASRAFQRELAFRAIGVDVEAQPCGGVVDAIEQGDEILAEALVRSHVEALKRRMPHPQAAILGCTHYPLMEATFQEALGPEVTVYSQANLVAESLADYLARRPEFVGQGTESKFLTTGDPRSVSNKATQFLRRRITFEAA
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.