PharMolix/UniProtQA huggingface dataset:
Protein: CAD13_BOVIN
Sequence: MQPATPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHIDQPAEFIEDQAILNLTFSDCKGNDKLHYEVSSPYFRVNTDGSLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPEGSKFRLTGKGVDQEPKGIFRINENTGSVSVTRNLDRETIATYQLFVETVDVNGRTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAMGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGSSSTATVHITVLDANESPVFYPDPMMVTKQENISVGSVLLTVNATDPDSLQRQTIRYSVYKDPAGWLNINPINGTVDTTALLDRESPFVHNSVYTALFLATDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGATDKDLHPNTDPFKFEIHKQTVPDKVWKISKINNTHALVSLLQNLNKANYHLPIMVTDSGKPPMTNITDLRVQVCSCKNSKVDCNAAGAPHFSAATALLLSLFSLARL
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  May act as a negative regulator of neural cell growth (By similarity).
What are the official names of this protein?
Cadherin-13.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: MRS2_MACFA
Sequence: MECLRSLPCLLPRAMRLPRRTLCALALDLTSVARPVAACGRAANLVGRSRAAQLCGPGRLRVAGEVHRLRTSDVSQATLASVAPVFTVTKFDKQGNVTSFEKKKTELYQELGLQARDLRFQHVMSITVRNNRIIMRMEYLKAVITPECLLILDYRNLNLEQWLFRELPSQLSGEGQLVTYPLPFEFRAIEALLQYWINTLQGKLSILQPLILETLDALVDPKHSSVDRSKLHILLQNGKSLSELETDIKIFKESILEILDEEELLEELCLSKWSDPQVFEKSSAGIDHAEEMELLLENYYRLADDLSNAARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFGMNLESSLEEDHRIFWLIIGIMFMGSGLIWRRLLSFLGRQLEAPLPPMV
What is the function of this protein?
Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix.  Required for normal expression of the mitochondrial respiratory complex I subunits.
What are the official names of this protein?
Magnesium transporter MRS2 homolog, mitochondrial, MRS2-like protein.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PYRR_CORGB
Sequence: MSERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADRVMLLGIPSGGVPLARRLAEKIEEFSGVSVDTGAVDITLYRDDLRNKPHRALQPTSIPAGGIDNTTVILVDDVLFSGRTIRAALDALRDVGRPNYIQLAVLVDRGHRQLPIRADYVGKNLPTARAEDVSVMLAEIDGRDAVTLTREDSEGDS
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: AQP7_LACBS
Sequence: MSGQHQITEQSSRNPLSRVSTLLPEKPLSPTSTYAGTQKHPEAPRQSSFLIQLQNIRNAIRKPMAEFFGVALLIIFGAGSACQVVLSTNPDVASSARGSFLSINFGWAIGIAMGVWVSGGISGGHINPAITIAMATYRGFPWRKVPSYILAQVLGGVVGAGLVYANYIHAIDIFEGGHHIRTQATASLFATYALPYMTQASCFFSEFLATAVLSMMVFALTDKRNHSPTNGLLPFALFILFVGLGASLGMETAYALNPARDFGPRLFLAMAGYGKALFNYRSQYWLWAPIIAPVLGAQAGGLLYDTFLNDGDNSPIKWRCASSQEHQLAEVV
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes (PubMed:21352231).  Acts as thre most efficient Laccaria water channel (PubMed:21352231).  In addition to water, shows also strong ammonium transport activity (PubMed:21352231).  May be involved in fungal nitrogen (ammonium) support of the plant host in symbiosis (PubMed:21352231).
What are the official names of this protein?
Aquaporin Lacbi1:317173.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein: Y5797_PSEAB
Sequence: MRLIIVSGRSGSGKSTALNVLEDNGFYCIDNLPASLLPDLAQRALLHTELLQPQVAVSIDARNLPSQLQRFPELLQEVRDNHINCDVLYLDADDETLLKRFSETRRRHPLTTDTRSLAEAIGDESQLLGPIADLADLKLDTTSLNLYQLRDTIKLRLLNKPEPGTAFLVESFGFKRGMPVDADLVFDVRCLPNPYWKPELRDHSGLEPEVREYLAAQPDVEEMYQDIVGYLNKWLPRFAASNRSYVTVAIGCTGGHHRSVYLAERIGAALRDSLKNVQIRHRDLSS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein PA14_57970.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RL16_DESVM
Sequence: MLSPRKVKFRKWQKGRLRGMATRGATVSFGDIGLKAVEHGKLSSQQIEAARIAMMRHIKRGGKVWIRIFPDHPVTAKPLETRQGSGKGAPVGWCAPVKPGRVLYEIKGVSLELAKEALTRAAHKLPIKTTIVVREGL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: Y1212_PARMW
Sequence: MQVEWSWFQQFQLEGVLLERWLLQLASAVVALLPIGLAIRWSRSLDPSPETASTVRLEGWRYSLTLLLAIALQLVSLAVINGLILQAIDDSMNLASGWQVSIHQSQLPVLTLISLVAVMQPRLRRLLPWFVSTAVVLIAARAWGVWALAWSIPLSGLQEPFLKADVSFALGRFAALQLLIALLSSGALFCLGNGLQTLLTRPPALSDWSCAVPGPRNRRLLMLMAALVLVLLAGQCWLSRHALLWHQHGIVAGAGWLQQAVTEPFRMLLTVELLLLALAVMLPSSLLLRRRLLGVLAVTLALGFSLTPLSRWLILRPQELSLQTPYLEEAIRSTRHAFQLDRITRGSYKPEPSLTKADIVQGASTLSNLRLWDSAPLLETNRQLQQLRVYYRFPQASVDRYPLSPQGDTPQQVILSARELDQSALPRRSKTWLNRHFVFTHGYGFTVSPVNTRGDDGLPEYFISDLGTDTRIQGNRELGIEREDVERAIPVEDAALYFGMLRSPYAVAPTRVDEFDYPEGDLNVYTHYRGSAGVPIGHWLQRVAAATYLGEPRLLTAGSIDHSSKLLIRREVRDRVQAIAPFLDLRGDPYLISIPQSGQPTSASNQHQYWVVEGFTHSSTYPYSSAVSNSDSDRYLRNSVKAVVDAYNGSVQLFISEPDDPLIRGWARVFPQLFQPLDAMPSSIRDHLRVPKELFDVQVKQLQRYHVEDPRVFYSGDDVWQVPLEVYDGEQISVRPYHITAQVQDRSNSEFLLLQPLTPLARPNLTAWLAARNDGKHYGDLVQIDFPKDTPILGPEQVQALINQDPEISKVFGLWDRGGSQVVQGNLLVVPVGQCLLYVEPVYLRASKGGLPSLTRIVVSDGRTIAMADTLPGAIDRLMQKTLPPVATGS
What are the official names of this protein?
UPF0182 protein SYNW1212.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CNTB_ECOLI
Sequence: MSDYQMFEVQVSQVEPLTEQVKRFTLVATDGKPLPAFTGGSHVIVQMSDGDNQYSNAYSLLSSPHDTSCYQIAVRLEENSRGGSRFLHQQVKVGDRLTISTPNNLFALIPSARKHLFIAGGIGITPFLSHMAELQHSDVDWQLHYCSRNPESCAFRDELVQHPQAEKVHLHHSSTGTRLELARLLADIEPGTHVYTCGPEALIEAVRSEAARLDIAADTLHFEQFAIEDKTGDAFTLVLARSGKEFVVPEEMTILQVIENNKAAKVECLCREGVCGTCETAILEGEADHRDQYFSDEERASQQSMLICCSRAKGKRLVLDL
What is the function of this protein?
Converts carnitine to trimethylamine and malic semialdehyde.  Can also use gamma-butyrobetaine, choline and betaine as substrates.
What are the official names of this protein?
Carnitine monooxygenase reductase subunit, Carnitine monooxygenase beta subunit.
What is the protein family that this protein belongs to?
Belongs to the PDR/VanB family. CntB subfamily.
Protein: LEU1_PROM4
Sequence: MAKDPGRVLIFDTTLRDGEQSPGASLNLEEKLAIAQQLARLGVDIIEAGFPYASQGDFTAVQRIAEQVGGEEGPIICGLARASKADIKACGEAIAPAPKKRIHTFIATSDIHLEHKLRKTREEVIQIVPEMVHYAKSFSEDVEFSCEDAARSDPDFLYELIELAISAGAGTINIPDTVGYITPSEFGELIQGIDANVPNIDEAILSVHGHNDLGLAVANFLEAIKRGARQLECTINGIGERAGNAALEELVMALHVRRSFYNPFFGRDPESPTPLTAIRTEEITKTSRLVSNLTGMVVQPNKAIVGANAFAHESGIHQDGVLKNRLTYEIVDAKTVGLTDNRISLGKLSGRSAVRARLEELGYDLTRDDLNEAFAKFKDLADRKREITDRDLEAIVSEQVMQPDARFQLQLVQVSCGTTLKPTATVTLADQDGTEQTAVALGTGPVDAVCKALDSLAGESNELIEFSVKSVTEGIDALGEVTIRLRREGKIFSGHSADTDVVVAAAQAYVNALNRLIYFEKKNPIHPQHDLIKANL
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: BUR1_ASPFU
Sequence: MAIASLERDDHGNPRFRGCTSIRDFEFLGKLGEGTFGEVYKARSKKDGSIVALKKILMHNEKDGFPITALREIKLLKMLSHRNILQLKEMAVERSKGDGRKKPSMYMVTPYMEHDLSGLLENPAVNFTEPQIKCYMLQLLEGLKYLHGNRILHRDMKAANLLISNNGVLQIADFGLARPYDEPPPEPGKGGGEAKRDYTTLVVTRWYRPPELLLQLRRYTTAIDMWGVGCVFGEMFKGKPILAGSSDLNQTQLIFNLVGTPTEENMPGWSSLPGCEGVKSFGYKPGSLREVFKDQNPMAISLLEELLKLDWRKRINAIDAINHPYFSSPPFPARPGELPSFEDSHEFDRRRFRGQRGAIPPAPAGGSVDQQQTTEIAVFPVLHALAGSLHTGFKTILQSALLKTGMLYHMDLQTRGSRFQASLVQKIAACLLNLLCLLIHHGAWVIQIGRHVREVNAIISEDGPMGNWIHTSRLTVTLVDILEKGKAIVRVPLLIGVIWNSNTLMKGINRVILGTDVLQEREAGVLTFERLEQRIEHCTDDDKLVLVSTDAERLRQMNPVTLLVLNDSKFITHLLLSMTY
What is the function of this protein?
Serine/threonine-protein kinase involved in transcription regulation.  Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes.  Also required for histone H3 methylation.  Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase bur1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL21_METFK
Sequence: MYAVIKTGGKQYRVAAGDKLKVEKLAGEVGSEITLDKVLLVSDGDNTTIGSPLVQGASVQAKVVAHGRGDKVLIFKMRRRKHYRKTQGHRQSFTEIQIEKIAAK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: LPR2_ORYSJ
Sequence: MEKRRFLGVCLLVAVLVLRAAVLGRGDDGGGGGRLLDPGKLEMFVDELPDMPRMRGYGVAEGGKLVAGNLTIGMYETMWKFHRDLPATRVFAYGTSKETATVPGPTIEAMQGVPTYVTWTNHLPPRHFLPWDPTLTAAAPGSGVPAVVHLHGGVQHSGSDGHSLAWFTAGFAATGPRFSSPAAYEYPNQQPPGNLWYHDHAMGLTRVNILAGLLGAYRVASPAEEAALNLPSGEAFDRNLVLFDRDFLADGSLFMNRTGNNPSVHPQWQPEYFGAVVVANGKAWPYLRVRRRRYRLRILNASNARFFRLSLSGGLRFVHVASDSVYLARPVPTRAFLLAPSEIADVVVDFVESGNATAIVLRSDAPAPYPGDPGDKAETVPVMKFVIDDDDDALSTEPDTSSVPARLTSPSQYAKPDAREAVLMRRIAMYEYTKEGTDEPTHLYLNARSYMDPVTETPREGTSELWDVINLTDDNHPLHVHLALFVALEQRSLRDVDDLKECMMARGSGGGGADACGLERHLAGGRKHVVPKQERGWKNVFKVRPGTVTRLLVRFRPLSPPDSRRFPFDVAAGPGYVYHCHILDHEDNEMMRPMKIVR
What is the function of this protein?
Multicopper oxidase that may play a role in the maintenance of inorganic phosphate homeostasis.
What are the official names of this protein?
Multicopper oxidase LPR1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: CASC3_HUMAN
Sequence: MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPAYIPRKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRGSS
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:29301961).  Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD).  Stimulates the ATPase and RNA-helicase activities of EIF4A3.  Plays a role in the stress response by participating in cytoplasmic stress granules assembly and by favoring cell recovery following stress.  Component of the dendritic ribonucleoprotein particles (RNPs) in hippocampal neurons.  May play a role in mRNA transport.  Binds spliced mRNA in sequence-independent manner, 20-24 nucleotides upstream of mRNA exon-exon junctions.  Binds poly(G) and poly(U) RNA homomer.
What are the official names of this protein?
Protein CASC3, Cancer susceptibility candidate gene 3 protein, Metastatic lymph node gene 51 protein, MLN 51, Protein barentsz, Btz.
What is the protein family that this protein belongs to?
Belongs to the CASC3 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Nucleus speckle. Cytoplasm, Stress granule. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cell projection, dendrite. Note=Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner. Transported to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA (PubMed:15166247). In nuclear speckles, colocalizes with MAGOH. Under stress conditions, colocalizes with FMR1 and TIA1, but not MAGOH and RBM8A EJC core factors, in cytoplasmic stress granules (PubMed:17652158). In the dendrites of hippocampal neurons, localizes to dendritic ribonucleoprotein granules (By similarity).
Protein: RTL8A_HUMAN
Sequence: MDGRVQLMKALLAGPLRPAARRWRNPIPFPETFDGDTDRLPEFIVQTSSYMFVDENTFSNDALKVTFLITRLTGPALQWVIPYIRKESPLLNDYRGFLAEMKRVFGWEEDEDF
What are the official names of this protein?
Retrotransposon Gag-like protein 8A, Mammalian retrotransposon derived protein 8A.
What is the protein family that this protein belongs to?
Belongs to the FAM127 family.
Protein: SLYX_BRADU
Sequence: MTNEIKTLSERIDTLETRLAYQDDTIETLNQTITAQWKQIDALTRQIAQLSERLQEAETNAPGPANERPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: PANC_EDWI9
Sequence: MLILETVPLLRREVRRWRQEGKRIALVPTMGNLHDGHMALVNEAHARADVVIVSVFVNPMQFDRPDDLARYPRTLQEDCEQLNRHGVDLVFAPAAEEIYPQGVSQQTYVDVPALSSILEGASRPGHFRGVATIVSKLFNLVQPDLACFGEKDYQQLQLIRKLVADMGYGTEIVGVPIVRGEDGLALSSRNGYLDSDERRLAPRLYNIMMQLASQLENGERDLEALLEQTASRLRQAGFCPDELFIRDADTLGDVNVDTRTAIVLMAAWLGQARLIDNVRIAFNADA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_TREPS
Sequence: MALRVYNTLTRQQEHFQPWEHGHVRLYGCGPTVYNYPHLGNLRAYVFQDTVRRTLHFLGYRVTYVMNITDVGHLESDADSGEDKLVRSAQAHGHSVLQVAAHYRAAFFRDTALLGIEEPSIVCNASDCIQDMIAFIEQLLARGHAYCAGGNVYFDVRSFPSYESFGSAAVEDVQEGEDAARARVAHDTHKRDARDFVLWFTRSKFVRHALTWDSPWGRGYPGWHIGCSAMSMKFLGPRCDIHIGGVDHIRVHHRNERAQCEAITGAPWVRYWLHHEFLLMQLQKRAVHADMGSSVVSSFSKMSKSCGQFLTLSSLQERGFQPADFRFFLLSGQYRTQLAFSWDALKTARAARRSFVRRVARVVDAARATTGSVRGTSAECAAERVCESRASESELLLTDFRAALEDDFSTPRALSALQKLVRDTSVPPSLCVSALQVADTVLGLGIIQEATASLSAQVPAGDTLPQRPLPSEEWIGQLVRARAHARQTRDFPRADEIRRQLKAEGIELEDTHLGTIWKRV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXS1_XENTR
Sequence: MVRTRIQRLLTGINRRMMKLLIALALIAYVASVWGNFVNMSKSIQENGEQKMEKKIEEVIAPLREKIQNLERSFTQKYPPVKFLSEKDRKRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQSEEYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEQLTVYGSGEQTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPQEHSIVQFARLIKQLVGSGGEISFLSEAQDDPQRRKPDIRKAKLLLGWEPVVPLEEGLNKTIHYFRKELEHQANNQYIPKPKPARVKKGRTRHN
What is the function of this protein?
Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose.  Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
What are the official names of this protein?
UDP-glucuronic acid decarboxylase 1, UDP-glucuronate decarboxylase 1, UXS-1.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: PVG4_SCHPO
Sequence: MGRKKISIAPITDDRSRSVTFVKRKQGLYKKAYELAVLADCEVAVTVIDRKGRLHVFCSSDYQRTLQQLNTLSIYELKNRSHFSSSPVEESSTVSPETTTGSFTPLNNKHLKSQDQPLSDSQLDTGDSPATSETTVQDYNPQVQSYCRPEPLSSNHVRSCPPFPPTQHHHPHTRPPHHPPHPHFHNNNYPPPYCFQSPVSPGATVPLQHHSPYPSDNGFPGHRRQTHFAPYYYPQRATSPSLKQVPTYLGTHVLQQDQSTYDQKVLMPPASYLSSPNQYTLKNVSPGNPACPPFLYEHPNPQLTPEMFDVKQGSPIPPTAYSGSSCETSQHTIANTPFLAYDRSPSLTNQEAESSFQDVASISPHSLSDVKY
What is the function of this protein?
Acts in transcription regulation.  May bind to a MEF2-like typee II promoter sequence.
What are the official names of this protein?
MADS-box transcription factor pvg4, MADS-box transcription factor 2, Pyruvylated Gal-beta-1,3-epitope synthesis protein 4, PvGal synthesis protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL33_TREPA
Sequence: MAKRTAVELIALQCTGCKRRNYTTSRNRRNVQEKLELRKYCPFERRRVLHREAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RSGA_PASMU
Sequence: MSKRKLTQNQKRRIQSNNEKTLHRHQRREKKEIDWQDDMLGESQDGIVVTRYSVHADVEDAAGEIFRCNLRRTLSSLVVGDRVIWRKGNAQLQGVSGVIEAIKPRQNEIARPDYYDGLKVIAANIDRIIIVSSVLPTLSLNIIDRYLVICENAQIPAVIVVNKVDLLSDQERAEVEAQLRIYQQIGYQTLMISALSGENMEKLTALFDEGTSIFVGQSGVGKSSLINHILPEVNAQVGDISENSGLGQHTTTSSRLYHLRQGGQLIDSPGIREFGLWHLDQEQITRGYREFQYFLGTCKFRDCKHLNDPGCALREAMEQGKIHSVRFANYHRLIASLEETKSQRHFSSEN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_STRPM
Sequence: MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWEKRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: GLSL_MOUSE
Sequence: MRSMRALQNALSRAGSHGRRGGWGHPSRGPLLGRGVRYYLGEAAAQGRGTPHSHQPQHSDHDASHSGMLPRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLQDCMSKMQRMVQESSSGGLLDRELFQKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDAKEPTGGKVAAYIPHLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISVSTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEFMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSQRGINFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYHDSYLLSETQAEAAAETLSKENLESMV
What is the function of this protein?
Plays an important role in the regulation of glutamine catabolism.  Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate.  Increases cellular anti-oxidant function via NADH and glutathione production.  May play a role in preventing tumor proliferation.
What are the official names of this protein?
Glutaminase liver isoform, mitochondrial, GLS, L-glutaminase, L-glutamine amidohydrolase, LGA.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PYRE_TERTT
Sequence: MHAYQQQFIEMAIASQALKFGEFTLKSGRVSPYFFNAGMLHMGSNIAHLGRAYAQALVDSGHPVDMIFGPAYKGIPLAAATAIALADHHNRDLPYAYNRKEAKDHGEGGTLVGAPLTGKVAIVDDVITAGTAIREVLALLEQAKAEPAAIVIGLNRKERGQGSLSAIDELQQSTGVPVVSIIDLDHIMMYLEKAGDQQTSEKIALYREQYGSD
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: ATPE_RHORU
Sequence: MAETTEFELVSPERLLFSEPVEMVVVPGTDGDFGAMPRHAPLLSTVRPGVISTYNGGKVQRRIFVAGGFAEVTEDRCTVLADEAFDLASLSEEAVRARLQAADDRLKEATSEAEKAEAAQAKAIAEALLAARKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL24_DANRE
Sequence: MKVELCSFSGYKIYPGHGRRYARVDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEVSKKRTRRAVKFQRAITGASLAEILAKRNQKPEVRKAQREQAIRAAKEAKKAKQATKKQTTQSSKAPAKSAQKQKIAKPMKVSAPRVGGKR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (By similarity).  Plays an essential role in early embryonic development (PubMed:12006978).
What are the official names of this protein?
60S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1A_CMVY
Sequence: MATSSFNINELVASHGDKGLLATALVDKTTHEQLEEQLQHQRRGRKVYIRNVLGVKDSEVIRNRYGGKYDLHLTQQEFASQGLAGALRLCGTLDCLDSFPSSGLRQDLVLDFGGSWVTHYLRGHNVHCCSPCLGIRDKMRHSERLMNMRKIILNDPQQFDGRQPDFCTQPAADCKVQAHFAISIHGGYDMGFRGLCEAMNAHGTTILKGTMMFDGAMMFDDQGVIPELNCQWRKIRSAFSETEDVTPLVGKLNSTVFSRVRKFKTMVAFDFINESTMSYVHDWENIKSFLTDQTYSYRGMTYGIERCVIHAGIMTYKIIGVPGMCPPELIRHCIWFPSIKDYVGLKIPASQDLVEWKTVRILTSTLRETEEIAMRCYNDKKAWMEQFKVILGVLSAKSSTIVINGMSMQSGERIDINDYHYIGFAILLHTKMKYEQLGKMYDMWNASSISKWFAALTRPLRVFFSSVVHALFPTLRPREEKEFLIKLSTFVTFNEECSFDGGEEWDVISSAAYVATQAVTDGKILAAQKAEKLAEKLAQPVSEVSDSPETSSQTPDDTADVCGKEREVSELDSLSAQTRSPITRVAERATAMLEYAAYEKHLHDTTVSNLKRIWNMAGGDDKRSFLEGNLKFVFDSYFTVDPMVNIHFSTGRWVRPVPEGIVYPVGYNERGLGPKSDGELYIVNSECVICNSESLSTVYGRSLQTPTGTISQVDGVAGCGKTMPIKSIFEPSTDMIVTANKKSAQDVRMALFKSSDSKEACTFVRTADSVLLNECPTVSRVLEDEVVLLHFGQLCAVMSKLKAVRAICFGDAEQIAFSSRDASFDMRFSKIIPDETSDADTTFRSPQDVVPLVRLMATKALPKGTHSKYTKWVSQSKVRRSVTSRAIASVTLVDLDSSRFYITMTQADKASLISRAKEMNLPKTFWNERIKTVHESQGISEDHVTLVRLKSTKCDLFKQFSYCLVALTRHKVTFRYEYCGVLNGDLIASVARA
What is the function of this protein?
Involved in the virus replication.  Contains a helicase domain and a methyltransferase domain.  The methyltransferase domain is probably involved in viral RNA capping.  Involved in the formation of ER membrane spherular invaginations in which RNA replication complexes form (By similarity).
What are the official names of this protein?
Replication protein 1a.
What is the protein family that this protein belongs to?
Belongs to the bromoviridae replication protein 1a family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Peripheral membrane protein.