PharMolix/UniProtQA huggingface dataset:
Protein: MHR1_DEBHA
Sequence: MRKHLLDHLKTRKILGARIAKGEKTEQDLINLNMAPQVFMFKNLFSGQVLYSQVPAFHQDQIDEQFTRPNWENRKPSRRNDLWRIMCVANFENYEYAIAAYKGLVQLRQVRDVVQKKEAKALRKKNDEGNVWFSGQYRPTYSQEAVADLSHVIDEFELEGTSVMWESLWRKGEDTHWRSDLVEHDTLPPFNPRDQTILLDELRAKAVEEFANLRQQAQQSEQQSQSELESQTA
What is the function of this protein?
Transcription factor involved in regulation of RNA polymerase II-dependent transcription.  Also involved in regulation of mitochondrial DNA recombination, maintenance and repair, and generation of homoplasmic cells (By similarity).
What are the official names of this protein?
Mitochondrial homologous recombination protein 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL67 family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: DUSB_SALTI
Sequence: MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSSNPQVWESDKSRLRMVHVDEPGIRTVQIAGSDPVEMADAARINVESGAQIIDINMGCPAKKVNRKLAGSALLQYPDLVKSILIGVVNAVDVPVTLKIRTGWAPEHRNCVEIAQLAEDCGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPIIANGDITNPHKARAVLDYTGADALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCTHVRELHDFYGQAKGYRIARKHVSWYLQEHAPDDQFRRTFNAIEDASEQLEALEAYFENFA
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
tRNA-dihydrouridine synthase B.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusB subfamily.
Protein: YIDD1_BACLD
Sequence: MKRAAIIFIRFYQKAISPLFPPTCRFYPTCSNYGLEAIQRFGFIKGSYLLIKRLLKCHPLHPGGFDPVPNQTDQKKEGDSD
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor 1.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DPO4_HALS3
Sequence: MPAGERLPGAPAREERIVVHVDMDCFYASCERRREPALRGAPVVVGMGYEPDQTVGAVATASYEAREYGVESAQAISAALERLPRKADAPDASAAGYYRPVDMAYYESVSESVSEILHGLGDPVREVSIDEAYLDVTDRTAWDVAAGFGRHIKQRIARSVGVPASVGIAPDMSTAKLASDHEKPDGLVVVPPESVQSFLAPLDVADLHGVGPVHARALRERGIETVGELADADPYVLEAAFGERGREFHRRARGADSRPVEPRGKPKSLSRESSFDGATESFDRVREQAAALSGAVADRASRTNASYRTIGVKVVTPPYDVQTRAESLPGPVDDPALLEAVSQSLLDEFEGAAVRKVGVRVSNLVFSEREQATLAGFSGDETGDGGGHEGGACGGAGRGSCGGQTTLDEFT
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TROPD_TALSN
Sequence: MAYGSQLTLLSGGQSIIILLIVSFLAWRFRVWFRLRHIPGPLGASLTNFVRMSWVFTKKAHLIHQELHQKYGDVVRFGPNMVSISDPASIHIIYPMRKGLVKNDFYVPLRPYTRNRGAIPNVFTALDEDLHMKLKYPVASLFSLSNVSKFEVLVDEVLSVIDEQLDRRFASHGEIFDLTEWLQFFAFDVMGTMTFSKRYGFLEEGKDVGGMLNAIGQFMKQAAPVMQNPWLDRVLYKNRIADSLKRTPGSDIMKFVVAAINERQKSASEDEDFTKARKGKNDFLDEYIITQKKDSNIPPWFVTAWTISNVLAGSDSVGTVMKTTMYNLLTNPRTLEKLHAELVAANVSRPRPRWSEVHNLPYLDAVVQEALRVHPPFALPFERIVPEGGLHISGQYIPANTVIGASPYVVNRHKPTYGDDAELWRPERWLEGGPEVRKKRDDGLLTFGAGRRICLGKHIGIFEVKKLIPFLVLNYDISIVKPETFLAENEWFFRQSNLLAQIRRRPLESVEPNV
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the tropolone class of fungal maleic anhydrides (PubMed:22508998, PubMed:24863423).  The pathway begins with the synthesis of 3-methylorcinaldehyde by the non-reducing polyketide synthase (PKS) tropA (PubMed:22508998).  3-methylorcinaldehyde is the substrate for the FAD-dependent monooxygenase tropB to yield a dearomatized hydroxycyclohexadione (PubMed:22508998, PubMed:24863423).  The 2-oxoglutarate-dependent dioxygenase tropC then performs the oxidative ring expansion to provide the first tropolone metabolite stipitaldehyde (PubMed:22508998, PubMed:24863423).  Trop D converts stipitaldehyde into stipitacetal which is in turn converted to stipitalide by the short-chain dehydrogenase/reductase tropE (PubMed:24863423).  The next steps involve tropF, tropG, tropH, tropI and tropJ to form successive tropolone maleic anhydrides including stipitaldehydic, stipitatonic and stipitatic acids (PubMed:24863423).
What are the official names of this protein?
Cytochrome P450 monooxygenase tropD, Tropolone synthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PTIP2_MOUSE
Sequence: MCWLRAWSHILLPVFLSVALIQLIFNLSDHKTKTHHHWKRKIEAKYVEKECAQKETCPVCTRDKRCIWCREEKVCKKYCFPYSDCKFNSIFWANCNVDLFGIVMLILIVILALAFLWYCLAYYFYMQQHMALYARHGQVPVYNWDAPGDW
What are the official names of this protein?
PTTG1IP family member 2.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DEFI_TRYDI
Sequence: VTCDLLSFEAKGFAANHSLCAAHCLAIGRRGGSCERGVCICRR
What is the function of this protein?
Antibacterial peptide.  Affects Gram-negative bacteria including methicillin-resistant Staphylococcus aureus.
What are the official names of this protein?
Defensin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPIA_XANOR
Sequence: MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGHIGHRIKGAVSSSEQSTARLRQHGIEVLDLNHTGNLSLYVDGADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGKFPLPVEVIPMARSLVARQILALTGGQPVWRDVVLTDNGNVVLDVHNLQITDPVALERSLNQIPGVVCVGLFARRPADVVIVGGEPPRVL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PTPA1_DICDI
Sequence: MATTQQPEATEHQHFGVVEIKDLENHKFIKPVKVVTNEDDIKKFLRSGACRDLLEYIQTLSDKIKSKPNSTKTQNSNEIKNIVSMLNEISVYIDNIPPLAQPMRYGNKAYRTFYQKLLDNVEELHKHLLPQSMHSSIIELSSYLMDAMGNQTRLDYGTGHELHFVVWTYCLRRIGFLKSTDEEDIVLNVFTTYLDLVRKLQRVYGLEPAGTHGVWSLDDYQFIPFIWGASQLIGNPFDIKPASVTIEKVVDQYYKEYLYIACIKYINTVKKGPFHEHSRDLFNISGAASWQKINTGMMKKFYDDVLSKVPIIQHFLFGSLISFSV
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase (By similarity).
What are the official names of this protein?
Probable serine/threonine-protein phosphatase 2A activator 1, Peptidyl-prolyl cis-trans isomerase PTPA-1, PPIase PTPA-1, Rotamase PTPA-1, Phosphotyrosyl phosphatase activator 1.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNA_THEKO
Sequence: MNEIKGIERAVQVEVPRPRFLLLAFTDINGSLKGMEIPMERYEEAVEDGVSFDGSSIPGFEGIEDSDLIFKADPSTYAEIPWEGIGRVYGYIYKGDEPYQADPRGILKRVLERLEKEGLKAHIGPEPEFYIFKKNGTWELHIPDSGGYFDLVGLDKAREIRREIALYMPYLGLKPEVLHHEVGKAQHEIDFRYDEALRTADNIVSFKHVVKAVAELHGYYATFMPKPIYGFPGNGMHLHISLWKDGENVFIGEDGLSDTALHFIGGILKHAKALAALTNPTVNSYKRLVPGYEAPVYISWGYRNRSALIRVPAFKGSGARIEYRCPDPSANPYLALAGILMVGLDGIKKKVEPDSYVETNVYEMDDAERERLGIDTLPGSLGEALEELKKDKTVREALGGAYKNFIDYKEREWEEYIEYLSSRDIPIDTKKVTEWELERYFYV
What is the function of this protein?
Carries out the ATP-dependent synthesis of glutamine from ammonium nitrogen and glutamate.  Exhibits both L-gamma-glutamylhydroxamate synthetase and gamma-glutamyltransferase activities when using hydroxylamine as substrate; in fact, the enzyme possesses low biosynthetic activity, suggesting that the reaction is biased towards the degradation of glutamine under ammonia-rich conditions.  Might play some role in ammonia assimilation under ammonia-starvation conditions.  Can also use GTP instead of ATP in the synthetase reaction, but not CTP or UTP.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASIP_MACNE
Sequence: MDVTRLLLATLLVFLCFFTAYSHPPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKNSKQISRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRDSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_DEHMB
Sequence: MPTTNIKELLEAGAHFGHQTSRWHPRMKKYIFTKRNGIHIIDLEKTVVMLDKACNYINQVVSDGGKVLFVGTKKQAQEILAEEAKRCGMYFINQRWTGGILTNFHSIQSRIDYLVRLEDQQARGDFSRLPKKEAQKLGEEIARLNRTMGGFKEMTRLPDVIFVVDPIKEKIAMAEAKRMGVPLVAMVDTNCNPDEVDYPVPSNDDAMRAIKLICSKMADAVIEAQNAMKVTEVETTGEAQAETAG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: BRRF1_EBVG
Sequence: MASSNRGNARPLKSFLHELYLKHYPEVGDVVHLLNTIGVDCDLPPSHPLLTAQRGLFLARVLQAVQQHKLLEDTIVPKILKKLAYFLELLSYYSPKDEQRDIAEVLDHLKTNRDLGLDDRLWALIRKLRQDRHHASVNVLMPGSDYTAVSLQYYDGISIGMRKVIADVCRSGYASMPSMTATHNLSHQLLMASGPSEEPCAWRGFFNQVLLWTVALCKFRRCIYYNYIQGSIATISQLLHLEIKALCSWIISQDGMRLFQHSRPLLTLWESVAANQEVTDAITLPDCAEYIDLLKHTKHVLENCSAMQYK
What is the function of this protein?
Enhances the ability of BRLF1 to induce lytic infection by cooperating with it to transcriptionally activate the BZLF1 promoter.
What are the official names of this protein?
Transcriptional activator BRRF1.
What is the protein family that this protein belongs to?
Belongs to the lymphocryptovirus BBRF1 family.
Protein: MOAC_BRUME
Sequence: MSGKLTHIDQTGAANMVDVGSKDETERQAVAEGAVRMKPETLALILEGNAAKGDVIGTARLAGIMAAKRTSDLIPLCHPLMLTKVAVEIEPDENLPGLRVRALARLKGRTGVEMEALTAASVTCLTIYDMAKAVDRHMEIGSIRVIEKSGGKSGDWAVSDPASMR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: CMR1A_PYRFU
Sequence: MFIEEFEIESITSTHLLEVLTREYPEVRSPSIKGAMRWWFRALAGSYFGDDAQKLKEIENQVFGSTKERSRVKISVTPLSSPKRLNLKEFKDKNVGYIWFSINLLGKRGTITHYYPPGSRFRVVLESPSERVIKLATLSLWALVSLGSVGFRSRRGTGSMKIVRASSEVLEDLGLTTEFNSIDEFKDSLKRVLDVTGEILGVKNSETNKSLPSYATLKFSDVEVFGPGKNTWEVLAQFNNSYKEYLRRRIKKYQRIIFGLPRFKLRGVRKDLRRASPLWFGVVEIGGKPYGRIIKFFQSTFHPEVRSKHIVDWNVLSNFDWFISSRLPVTKVWGGWSG
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), formerly called psiRNA (prokaryotic silencing) in this organism.  Part of the Cmr ribonucleoprotein complex which has divalent cation-dependent endoribonuclease activity specific for ssRNA complementary to the crRNA (target RNA), generating 5' hydroxy- and 3' phosphate or 2'-3' cyclic phosphate termini.  Cmr4 is probably the subunit that cleaves target RNA (PubMed:25280103).  Cmr complex does not cleave ssDNA complementary to the crRNA.  Cleavage of invading RNA is guided by the crRNA; substrate cleavage occurs a fixed distance (14 nt) from the 3' end of the crRNA.  In vitro reconstitution shows Cmr1-2 and Cmr5 are not absolutely necessary for target cleavage (PubMed:19945378).
What are the official names of this protein?
CRISPR system Cmr subunit Cmr1-1, CRISPR type III-B/RAMP module RAMP protein Cmr1-1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR system Cmr1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_ECOHS
Sequence: MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: QUEA_STRR6
Sequence: MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFHSIIDMLEPGDALVMNDTRVLPARLYGQKVETGSHVELLLLKNTSGDEWEVLAKPAKRLKVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQRIFLEVLESLGEMPLPPYIHEKLDDRERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDNLDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSGWTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFSFGDAMFIY
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_STRA1
Sequence: MTSVFKDSRRDLRERAFQTLFSLETGGEFIDAAHFAYGYDKTVSEDKVLEVPIFLLNLVNGVVDHKDELDTLISSHLKSGWSLERLTLVDKSLLRLGLYEIKYFDETPDRVALNEIIEIAKKYSDETSAKFVNGLLSQFITNEN
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PAGBP_PSEAE
Sequence: MKKVCALALSILTTIGATAADSAWAAQTSVHLYNWYDFIAPETPKAFQKETGTRVVLDTFDSAETAQGKLMVGRSGYDVVVITSNILPGLIKAGVLQELDRDRLPHWKNLDADILGKLQANDPGNRYAVPYLWGTTGIAYDVDKVRKLLGPDAPVDSWDLVFKEENISRLSQCGVATLDSSTELVSIALNYLGLPHNSQNPEDYQKAQELLLKVRPYIRYFDSSRVDTDLSNGNVCVVVGWQGTAYMAQVNNEQAGNGRHIAYSIPREGSLVWAENMVLLKDAPHPQQGYALIDYLLRPEVIARTSNYVGYPNGNQAALPLVERKLRENPAVYLSKETMATLFPLETLPLKVERIRTRVWSRVKTGS
What is the function of this protein?
Binds putrescine and agmatine.
What are the official names of this protein?
Putrescine/agmatine-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PGM_NEIGO
Sequence: MASITRDIFKAYDIRGIVGKTLTDDAAYFIGRAIAAKAAEKGIARIALGRDGRLSGPELMEHIQRGLTDSGISVLNVGMVTTPMLYFAAVNECGGSGVMITGSHNPPDYNGFKMMLGGDTLAGEAIQELLAIVEKDGFVAADKQGSVTEKDISGAYHDHIVGHVKLKRPINIAIDAGNGVGGAFAGKLYKGLGNEVTELFCEVDGNFPNHHPDPSKPENLQDLIAALKNGDAEIGLAFDGDADRLGVVTKDGNIIYPDRQLMLFAQDVLNRNPGAKVIFDVKSTRLLAPWIKEHGGEAIMEKTGHSFIKSAMKKTGALVAGEMSGHVFFKERWFGFDDGLYAGARLLEILSASDNPSEVLDNLPQSISTPELNISLPEGSNGHQVIEELAAKAEFEGATEIITIDGLRVEFPDGFGLMRASNTTPILVLRFEADTQAAIERIQNRFKAVIESNPHLIWPL
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase, PGM, Glucose phosphomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M1_INBLE
Sequence: MSLFGDTIAYLLSLIEDGEGKAELAEKLHCWFGGKEFDLDSALEWIKNKRCLTDIQKALIGASICFLKPKDQERKRRFITEPLSGMGTTATKKKGLILAERKMRRCVSFHEAFEIAEGHESSALLYCLMVMYLNPENYSMQVKLGTLCALCEKQASHSHRAHSRAARSSVPGVRREMQMVSAMNTAKTMNGMGKGEDVQKLAEELQNNIGVLRSLGASQKNGEGIAKDVMEVLKQSSMGNSALVRKYL
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: NDUBA_MOUSE
Sequence: MPDSWDKDVYPEPPSRTPAPSPQTSLPNPITYLTKAYDLVVDWPVTLVREFIERQHAKNRTYYYHRQYRRVPDITECKEGDVLCIYEAEMQWRRDFKVDQEIMNIIQERLKACQQREGENYQQNCAKELEQFTKVTKAYQDRYLDLGAYYSARKCLAKQKQRMLEERKAARQEAAA
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10, Complex I-PDSW, CI-PDSW, NADH-ubiquinone oxidoreductase PDSW subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB10 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: DBH_DEIRA
Sequence: MTKKSTKAPAKKAAPAAKAAPAAKRGAAADSGKVAKTQLVEMVADQTGLTKKQSEEAISSMLECVVSALQSGKSVGLPGLGTLSVKETAARTGVRPGTSEKIQIPAGKKVAFKVASTLKGNL
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RIR2_SPISO
Sequence: MLSINTTRKENELSGNLGKMKITEENKPKKVLGEITNFQRSTQKTPLKQEIKPVVKKSQQVEPLLADNPRRFVVLPIQYHDIWKMYKKAEASFWTAEEVDLSKDMAHWESLKKEEKHFISHVLAFFAASDGIVNENLVERFSKEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPQERDFLFNAIETMPCVKEKADWAMRWINDDSSSYAERVVAFAAVEGIFFSGSFASIFWLKKRGIMPGLTFSNELISRDEGLHCDFACLMFSHLVNKPSQERIHQIIDEAVKIEQVFLTEALPCRLIGMNCDLMRQYIEFVADRLLLELKCDKLYNKENPFDFMEHISLEGKTNFFEKRVGEYQKMGVMSGGNTGDSHAFTLDADF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit, p41.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: DPO3_CLOPE
Sequence: MSNEFVKQINRSIKSDDNLNDLEFEITKFQLLKKSNTLRTIIKSKDQLSEEQKKIIKQYIKKAIGFEINIEIMYYIDISDITLKQVVDQHWNHVCEKIIEKHPVLKEVLLNSPIVIEGEKIIIKNGSEFLCTFVNKKHIDREIKGYIKSFFGINSLVEVKYDESLANKNYNDEKLNENKEIAKKVIETMKAQAAQEKPVKKESSDNKHKSNGGNKGGYEKKSYKDEPKNENTILGRNIQGDTIDISSIDMGSGIVTISGDVFKTDIFETKTGRIILTFFITDYTSSIAVKCFLRDKDKEHVLENVKKGLYCKVRGEATMDPYAKEVVIMARDINKLTKIERMDTAEEKRVELHMHTTMSSMDAVTAASKIVERAAKFGHKAVAITDHGVVQAFPDAQIAAKKNNIKVIYGVEGYLADNGTPIVINGHEESFDDEYVVFDIETTGFSSKNDKIIEIGAVKLKDGEIVDSFSTFVDPKVNIPYKITELTSITQNMVNGQPTIDEVLPKFMEFVGNSVLVAHNAAFDVGFIKKNLMDMGKTLKNPVMDTVPLARYLYPDLKKVKLNLVAKHLGISLENHHRAVDDAKATAEILKFSFKKMKEEMDIHDVKTLNEKYLSNIDVKKLPLHHIIILAKNQTGIKNLYKLVSMAHLDYFARRPRLPKSIITEYREGLIIGSACEAGQLYKAVLEGKTDGELKEIASFYDYLEIQPIQNNEFLIRKGNVKDEEELRELNRKIYDLGKEMDKPVVATCDCHFLDPNDEVFRRIIMAGQGYGDADNQPPLYFRTTNEMMKEFEYLGEEACREVVIENTQKIADMVEAVKPIPDETFPPKIEGAEEEIRNMTMNKVHSIYGENLPEVVQKRLDKELNSIINNGYAVLYLIAQKLVAKSLEDGYLVGSRGSVGSSFVATMSDITEVNGLPPHYVCPNCKKSEFFLDGSISSGADLPDKNCPDCGAKYIKDGHDIPFETFLGFEGDKEPDIDLNFSGEYQAVVHKYTEVLFGKGYVFKAGTIGTVAEKTAYGFVKKYLQERGLVVSQAEIERLTIGCTGIKRTSGQHPGGIMVVPNDNEIYNFCPIQHPADDVNTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTGLDPKTIPLNDPKVISLFTSPDALGVTKEELGCEVGSYGLPEFGTKFVRQMLVDTQPKSFADLVRISGLSHGTDVWLNNAQYFIKEGYTTLKDCIATRDDIMVYLMYKDLPPKTAFTIMEKVRKGKGLSEEDEALMREKNVPDWYIESCKRIKYMFPKGHAVAYVMMAVRIAYYKVYYPEAYYTTYFTVRADDFDADLICKGEEAIKAKMEELNSLGNNISVKEKGLLTILEISYEMYKRGLNFLKVDLYKSEATKFKIEEDGIRPPLNALQGVGDNAAKSIVECRVNGEFISKEDLRLRSKVSKTVIETLDNHGCLEGMQESNQLSLFG
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_MICAN
Sequence: MTAFQLQAPFQPTGDQPAAIDQLVDSLQNQHRFQTLLGATGTGKTFTIAAVIEKIGRPTLVLAHNKTLAAQLCNELRQFFPNNAVEYFISYYDYYQPEAYIPVSDTYIEKSSSINDEIDMLRHSATRSLFERRDVIVVASISCIYGLGMPAEYLKAAISLTVGQEFDQRQLLRALVSVQYNRNDLELTRGRFRLKGDILEIVPAYEDRVIKIDFFGDEIESIRYLDPLTGEVLQKLERISIYPARHFVTPEERLEVACRDIKTELDNRLLELEKAGKLLEAQRLDQRTRYDLEMLQEVGYCNGVENYSRHLAGRLAGEPPECLVDYFPEDWLLVVDESHVSVPQIRGMYNGDQSRKKVLIDHGFRLPSAADNRPLKSEEFWQKVNQCIFVSATPGDWELEQSENRIVEQIIRPTGVLDPEIFVRPTEGQVDDLLGEIKERVQLNERVLITTLTKRMAEDLTEYLQERGIKVRYLHSEIQSIQRIEIIQDLREGVFDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRATRSLIQTIGRAARHIRGQAILYGDNLTDSMINAIEETKRRRAIQQEYNQKHGIIPQPIVKRSSNSILAFLDISRRLNSQQLEQVCENIEELSLEQIPELIQQLEAQMKEAAKNLEFESAAKYRDRIKQLRDKLLNHVR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.