PharMolix/UniProtQA huggingface dataset:
Protein: TRER_SALTY
Sequence: MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSERTRERVEAVMNQHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQFSPTLVMEHLGMLRRRNIDGVVLFGFTGITEELIAPWKASLVLLARDAQGFASVCYDDEGAIHILMQRLYEQGHRNISFLGVPHSDITTGKRRHDAYLAFCKKHKLHPVAALPGLAMKQGYEHTASVIMPDTTALVCATDTLALGASKYLQEQRIETLQLASVGNTPLIKFLHPEIVTVDPGYAEAGRQAASQLIEQINGRCDPRRIVIPSTLA
What is the function of this protein?
Repressor of the treBC operon.  It is able to bind trehalose-6-phosphate.
What are the official names of this protein?
HTH-type transcriptional regulator TreR, Trehalose operon repressor.
Protein: RPOB_STAA3
Sequence: MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEESKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDATIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERLRPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMDVLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELTHKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQIDYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSGTCYNQRPIVAVGDVVEYNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPLGVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENISRPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PNP_SHISS
Sequence: MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRVYTGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRIRLSIKEATEQSQPAAAPEAPAAEQGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIR3_ARATH
Sequence: MSKLILILTAQILLLTATALAGKNGEDFARTINRKHLGLGKKEKLTHLRVYWHDIVTGRNPSSIRIQGPVAKYSSSSYFGSITMIDNALTLDVPINSTVVGQAQGMYVGAAQKEIGLLMAMNLAFKTGKYNGSTITILGRNTVMSKVREMPVVGGSGMFRFARGYVEARTKLFDMKTGDATVESNCYILHY
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
What are the official names of this protein?
Dirigent protein 3, AtDIR3.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: SSPA_STAAC
Sequence: MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQSSKQQTPKIQKGGNLKPLEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQNIEDIHFANDDQPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNPDNPDNGDTNNSDNPDAA
What is the function of this protein?
Preferentially cleaves peptide bonds on the carboxyl-terminal side of aspartate and glutamate.  Along with other extracellular proteases it is involved in colonization and infection of human tissues.  Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB.  It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells.  May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM.  May be involved in the stability of secreted lipases (By similarity).
What are the official names of this protein?
Glutamyl endopeptidase, Endoproteinase Glu-C, Staphylococcal serine proteinase, V8 protease, V8 proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYI_THET8
Sequence: MFKEVGEPNFPKLEEEVLAFWKREKIFQKSVENRKGGPRYTVYEGPPTANGLPHVGHAQARSYKDLFPRYKTMRGYYAPRRAGWDTHGLPVELEVEKKLGLKSKREIEAYGIERFNQACRESVFTYEKEWEAFTERIAYWVDLENAYATLEPTYIESIWWSLKNLFDRGLLYRDHKVVPYCPRCGTPLSSHEVALGYKEIQDPSVYVRFPLKEPKKLGLEKASLLIWTTTPWTLPGNVAAAVHPEYTYAAFQVGDEALILEEGLGRKLLGEGTPVLKTFPGKALEGLPYTPPYPQALEKGYFVVLADYVSQEDGTGIVHQAPAFGAEDLETARVYGLPLLKTVDEEGKLLVEPFKGLYFREANRAILRDLRGRGLLFKEESYLHSYPHCWRCSTPLMYYATESWFIKNTLFKDELIRKNQEIHWVPPHIKEGRYGEWLKNLVDWALSRNRYWGTPLPIWVCQACGKEEAIGSFQELKARATKPLPEPFDPHRPYVDQVELACACGGTMRRVPYVIDVWYDSGAMPFASLHYPFEHEEVFRESFPADFIAEGIDQTRGWFNSLHQLGVMLFGSIAFKNVICHGLILDEKGQKMSKSKGNVVDPWDIIREFGADALRWYIYVSAPPEADRRFGPNLVRETVRDYFLTLWNVYSFFVTYANLDRPDLKNPPPPEKRPEMDRWLLARMQDLIQRVTEALEAYDPTTSARALRDFVVEDLSQWYVRRNRRRFWKNEDALDREAAYATLYEALVLVATLAAPFTPFLAEVLWQNLVRSVRPEAKESVHLADWPEADPALADEALVAQMRAVLKVVDLARAARAKSGVKTRTPLPLLLVTAPTALEREGLKRFAHEIAEELNVKEVRVLEPGEEILSYRVLPNLKLLGRKYGKLVPKIREALQRERERAAALALKGEAIPLEVEGEALTLLPEEVLLEAEAPKGYQALEKDGYVAALKVEVTEALRMEGLARDLIRLLQQARKDMGLKVSDRIRVGYEAEGPYLEALKRHGPWIAEEVLATAFGEGLFGGFEARVEDEEGKAVFHLARAE
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_BACC0
Sequence: MKRRTARERAMQALYQMDITGELEPKVAVENTLDEGEETNEFLESLVVGFVENKEVIDEAIRQNLKKWKLERISIVDRSILRVAVYEMKYMEEIPHNVTINEAIEIAKTFGDEESRRFINGVLSNIKDTL
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: TRPD_XANOP
Sequence: MPITPQEALQRTIEHREIFHDEMVGLMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGAATVMREFSRRVDVSDHQHMVDIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSSKSGSADALEALGAVIELQPEQVADALAQTGIGFMYAPLHHPSMKVVAPVRREMGVRTIFNILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVGELRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLRVLDNVPGPALDIVALNAGAALYVAGLAGSIADGVLRARAVLADGSARARLDAYVAYTHQLAGQP
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ISPH_PSET1
Sequence: MEILLANPRGFCAGVDRAISIVERALDIFEKPIYVRHEVVHNRYVVDGLKSRGAVFVEELDQIPDDSIVIFSAHGVSQAVRTEAKRRDLKIFDATCPLVTKVHMEVTRASRKGIECILIGHQGHPEVEGTMGQYGNDGGGIYLVETVEDVAKLNVKNADNLFYCSQTTLSVDDTADVIDALRAKFPAIDGPRKDDICYATQNRQDAVRDLADKVDVLLVVGAKNSSNSNRLRELADKMGTKAYLIDDATNVQESWFTGINAVGVTAGASAPEVLVQQVITRLKELGGNQVTENPGEEENIVFAVPIELR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RS10_HALS3
Sequence: MQQARVRLAGVDPDDLDNICGEVQEIADKTGVKVSGPVPLPTKTLEVPSRKSPDGEGTATWEHWEMRVHKRLIDIDADERALRQLMRIQVPNDVNIEIVLED
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DNAJ_SYNP2
Sequence: MAGDFYEILGVSRDCGKDELKRAYRRLARQYHPDVNKDPGAEEKFKEINRAYEVLSEPETRARYDRFGEAGVSGAGAAGADYGDMGGFADIFETIFSGFGGMGTGATGGGRRRSGPMRGDDLRLDLKLDFKEAIFGGEKEIRIPHLETCKTCSGSGAKAGTSANTCGTCNGTGQVRRATRTPFGSFAQVSVCPTCNGEGQVIAEKCESCGGAGRKQETKKLKITIPAGVDSGTRLRVSREGDAGVKGGPPGDLYVYLAVNADKEFRRDGTNILSEIEISYLQAILGDTVKVKTVDGTEDLTIPAGLQPNKVLILEGKGVPKLGNPVSRGDHLITVKVMIPTKVSREEKELLHQLAKLKGTEHSKGGFEGLLGNLFHNK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_BUCBP
Sequence: MKKINPNNTESWKMLQNHFYEIKSFHIKELFKKDKNRFKKFSLKFDNRILVDYSKNRITSFTIKLLLKLANEMDLNNSIKSMFSGKIINETENRAVLHTALRNRSNSSIIHNGCNIMFDINKVLEKMKHFSNLVINRKWLGYTGKYITDIVNIGIGGSDLGPKMVIKALNSYRNHLNIHFVSNVDGANIFNVLKKLNPESTLFIIVSKTFTTQETIVNANTAKKWMLNAVNKNEFLDQHFIAVTTNAQEAMNFGIRYKNIFLFWDWVGGRFSLWSSVGLSIVLAVGFKNFEQLLDGAYMMDQHYLHTKFDNNIPVLLALIGVWYNNFFKSETEAIFFYDWNMNYFSSFLQQMNMESNGKNICRSGEFVNWQTGPIIWGEPGTNGQHAFYQLLHQGTKLIPSDFIISIIPKHPFKDHHKYLLSHFFAQTQALAFGKFNQKCNVHINDKKTFDERLSSISFHKVCKGNQPSNSIVLDQLNPYNLGILIALYEHKVFTQGVIFNIFSFDQWGVELGKLLAKEIFLNMNTTGSKNYEYDSSTNGLINFYKIHSNNT
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V1R41_MOUSE
Sequence: MNKANLLYTDTNMKTFLFSEVSVGISANSMLFIVHICILLGENRPKPINLYIAFLSLTQLMLLITMGLIVADMFMSQGIWDSITCQSLIYLHRLLRGLTLCATCLLNVLWTITLSPRSSCLTKFKHKSPHHISGAFLFFCALYMSFSSHLFLSIIATPNLTSEDFMYVTQSCSLLSMSYSRTSMFSTAIAIREAFLISLFALCSGYMVALLWRHKKQAWDLHSTNVSSKSSPEQRATRTIMLLMSFFVVLYVLENAVFHSRMKFKDGSMLYCVQIIVSHSYATVSPFVLICTEKRMIKFWGSMFGRIVNI
What is the function of this protein?
Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
What are the official names of this protein?
Vomeronasal type-1 receptor 41, Vomeronasal type-1 receptor A12, Vomeronasal type-1 receptor B9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NSS_INSVN
Sequence: MSSAMYETIIKSKSSIWGTTSSGKAVVDSYWIHDQSSGKKLVEAQLYSDSRSKTSFCYTGKVGFLPTEEKEIIVRCFVPIFDDIDLNFSFSGNVVEILVRSNTTNTNGVKHQGHLKVLSSQLLRMLEEQIAVPEITSRFGLKESDIFPPNNFIEAANKGSLSCVKEVLFDVKYSNNQSMGKVSVLSPTRSVHEWLYTLKPVFNQSQTNNRTVNTLAVKSLAMSATSDLMSDTHSFVRLNNNKPFKISLWMRIPKIMKSNTYSRFFTLSDESSPKEYYISIQCLPNHNNVETVIEYNFDQSNLFLNQLLLAVIHKIEMNFSDLKEPYNVIHDMSYPQRIVHSLLEIHTELAQTVCDSVQQDMIVFTINEPDLKPKKFELGKKTLNYSEDGYGRKYFLSQTLKSLPRNSQTMSYLDSIQMPDWKFDYAAGEIKISPRSEDVLKAISKLDLN
What is the function of this protein?
Forms filamentous inclusion bodies.
What are the official names of this protein?
Non-structural protein NS-S.
What is the protein family that this protein belongs to?
Belongs to the tospovirus NS-S protein family.
Protein: PUR9_BACAC
Sequence: MKKRALVSVSDKTGVVEFVKGLLEQGIEVISTGGTKKLLEENGLQVIGISEVTGFPEIMDGRVKTLHPNIHGGLLAVRDNETHVAQMNELGMEPIDFVVVNLYPFKETIAKPDVTFADAIENIDIGGPTMIRSAAKNHKFVSVIVDPVDYDVVLAELKENGEVAEETKRKLAAKVFRHTAAYDALISNYLTEQMGEESPETLTVTFEKKQDLRYGENPHQKATFYKAPFAATSSVAYAEQLHGKELSYNNINDADAALSIVKEFTEPAVVAVKHMNPCGVGVGTDIHEAYTRAYEADPVSIFGGIIAANREIDKATAEKLHEIFLEIIIAPSFSKEALEVLQSKKNLRLLTVNIEKATSASKKLTSVQGGLLVQEEDTLSLDESTISIPTKREPSEQEWKDLKLAWKVVKHVKSNAIVLAKDDMTIGVGAGQMNRVGSAKIAITQAGEKAQGSALASDAFFPMPDTVEEAAKAGITAIIQPGGSIRDEDSIKVADTYGIAMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: GCH42_DECAR
Sequence: MSTPTSNIPDVQNSADTRHIAINKVGIKSIRHPIKVQDKSAGIQHTIAMFNMYVGLPHNFKGTHMSRFVEILNSHEREISVENFPTMLRDMVVKLEAETGHIEMNFPYFINKTAPVSGVQSLMDYDVTFIGDICHGEIATSVKVVVPVTSLCPCSKKISEYGAHNQRSHVTVTAKTNDFMWIEEIVQLVEQEASCELFGLLKRPDEKYVTERAYDNPKFVEDMVRDVAARLNAEARVDAYVVESENFESIHNHSAYALIENDKKNPLAHA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2 2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: DCD_XANOR
Sequence: MSIKSDRWIKRMAEQHAMIAPFEPGQIKHDAAGQRIVSFGTSSYGYDVRCSREFKIFTNINSTIVDPKRFDPGSFVDVESDVCIIPPNSFALARTVEYFRIPRDTLVVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPARIYANEGVAQMLFFQSDEVCETSYKDRGGKYQGQTGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CA4A_CONSE
Sequence: MGMRMMFTVFLLVVLATTVVSIPSDRASDGRNAAVNERQTWLVPSTITTCCGYDPGTMCPTCMCDNTCKPKPKKSGRRND
What is the function of this protein?
Kappa-conotoxins bind and inhibit voltage-gated potassium channels.
What are the official names of this protein?
Kappa-conotoxin-like SmIVA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AAEX_SERP5
Sequence: MSLLPVMVIFGLSFPPIFFELLLSLALFFLLRRLLQPTGIYDFVWHPALFNTALYCCLFYLITCLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACEK_RHOPA
Sequence: MTATASHTRARPLGASEIEHATRIAEPDFDLLDALYRTDDPDDQARLLARVVLSAFDNYYAVSRRIPALAQAAFEARDWPVTVRLSKIRIGLYTACIDQLVPLLKAGLPELTTDEQLWPTAEAELLAAIEGRYEADFAFAFWQSLRRKLVSDEWRPVSYDAGSTARRTTSPAAVLKTTATTLPITAEVIAGILDEAGFRVPWRDRDGDAALAAQAIETALEPLSPRPGEPVKIEIADSGFLRNRGACLVGRIKLRDRGDMPMRNLPLLIALLNEKDGLVVDAVLTDSDELQYAFSSTLANYHATNPRYHELARLLYELMPKRPLGTQYSCIGFHHLGKVAVMSEILAEHRKTKEKLATAPGFKGTVAIAFTMPSSAYVLKIIRDHPTDDYKFDYFDGLDEVLRKYNLVHEIDRAGSMLDNIIYSNVKLDRAMFAPELLDELLEAGIGTVTLDRGALVFRHLIVQIKLTPLPLYLANASAAESRAAVINLGDCIKNNAAADIFNKDLDGRNYGVSRIRKVYLFDYDAVEPLTSVTVSRDGAAPGEFDNGMVFRPQEMLEGLRIDDPGLRRAFRDAHPELMQADYWEGMQQALRDGKVPKVMNYPASRRLRR
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMD_UNCRE
Sequence: MLLSSLISLALLSSQVVADPAWAPPDKGLKPEVARLLPPFLRYRRPIYAIAHRVVTVGGIKDAISHGANAFEVDMCADSIGEGWWANHDCTNGRKAGDSARKIFETFAAERKRGKTVTFVWLDFKNPDACVKNQGCSIEAIQQLCRDILEKQGIRVLYGFYKAEDSRAFKTIRNNLNDREAISLNGATTKVLKLFEGTAPKVSKHQRVMDYGDTYLDKGFGDCTEKDWYTCTELRQGADLRRKGKLGKVFAWTSTVNQGRLVDQLLGKAHVDGIIYGFKLTDYYDHADSRAAANDIISWVKRRRALYYMATNDNNPWIDIHKLFLYLLSWFSCILLLMMNEWTCPQDGA
What is the function of this protein?
Catalyzes the hydrolysis of sphingomyelin.  Sphingomyelinases D are produced by some spider in their venoms, but also by arthropods such as ticks, or pathogenic bacteria and fungi.  They might play a role in pathogenicity through different mechanisms, such as membrane destabilization and host cell penetration, but also pulmonary inflammation and cutaneous lesions.
What are the official names of this protein?
Sphingomyelinase D, SMase D.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelinase D/phospholipase D family.
What are the subcellular locations of this protein?
Secreted.
Protein: TM2D1_MOUSE
Sequence: MAAAWPAGRASPAAGPPGLLRTLWLVTVAAGHCGAAASGAVGGEETPKCEDLRVGQYICKEPKINDATQEPVNCTNYTAHVQCFPAPKITCKDLSGNETHFTGSEVGFLKPISCRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSSYIIDYYGTRLTRLSITNETFRKTQLYP
What is the function of this protein?
May participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42.
What are the official names of this protein?
TM2 domain-containing protein 1, Amyloid-beta-binding protein, mBBP.
What is the protein family that this protein belongs to?
Belongs to the TM2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TTCA_PSEA6
Sequence: MNHVSSTKPDTAPSKHLTSSHIDATDQNNKRLKKLTTKLRRKTGQAIADFNMIEEGDKVMVCLSGGKDSYTMLDMLLHMQKAAPISFSIIAVNLDQKQPGFPEHVLPNYLEGLGVDFAIIEEDTYSIVVDKVPEGKTTCSLCSRLRRGILYSNAIKMGVTKIALGHHRDDMLETLFLNMFHNGRLKSMPPKLTSDDGRNVVIRPLAYCAEQDIADYSILSGFPIIPCNLCGSQENLQRKQVKLMLAQWNTQFPGRIETMFKALQNVVPSHLADPGAFNFNDLDHSNSTSIEGDTAFDPLELTPVTKVDTLAVPITRID
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_FRAT1
Sequence: MTVMKFDLIKKEGKARRGKITFPRGDIQTPAFMPVGTYGAVKSLSPVELKEMGAEIILGNTFHLWLRPGTEIIKKHGSLHGFNGWDKPILTDSGGFQVFSLGKMRKLTEEGVTFKSPINSSKVFLSPEISMQVQRDLGSDIVMCFDECTPYPATEKEAKESMELSMRWAKRSKEAHGDNPSALFGIIQGGMYEHLRDESLAKLKEIDFDGFAIGGLSVGEPKEDMIRILDHTAHQMPEDKPRYLMGVGTPKDLVEAVYRGVDMFDCVMPSRNARNGHIFTSEGVIKIRNSKYKDDTSPLDPNCDCYTCKNFTKSYLHHLDKTKEILGSRLNTIHNLTFYQNLMKSIRKALDEGRFSEFRKEFLASYK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: DAPAT_CHLCV
Sequence: MQRNNNFSKLETSYLFSSIRQKIRAFREAHPDVSIIDLSIGDTTQPLHTAVMDTFTKSVQKLGNPETYRGYGPELGLSTLREKLSEVFYQGKVSPEEIFISDGAKMDIFRLLSLFGPGKTIAVQDPSYPVYIDTALLAGAKKVIKLPCRKETDFFPVIPQGEEIDIFCLCSPNNPTGTVLTKEQLEELITYANSHGSIILFDAAYSAFISDPSLPKSIFEIPEARSCAIEINSFSKSLGFSGVRLGWNVVPKDLRYSNGLPIIDDWKRFLHTTFNGASLPVQEAAITGASLFPNLEAIAHYRHNSSLLREALQKAEFSVYGGEHAPYLWVEVPKILPDEDFFDFFLTQYHIAITPGKGFGACGKGYVRFSSLGKIEDIMAACQRLTLTSVYDRMV
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: FAR6_CALVO
Sequence: ASGQDFMRF
What are the official names of this protein?
CalliFMRFamide-6.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEPF_STRZP
Sequence: MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALPMNQPSQSVGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAGNESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRLPDEDQQGEFGFDMKRNRVR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.