PharMolix/UniProtQA huggingface dataset:
Protein: 3BHS1_RAT
Sequence: MPGWSCLVTGAGGFVGQRIIRMLVQEKELQEVRALDKVFRPETKEEFSKLQTKAKVTMLEGDILDAQYLRRACQGISVVIHTAAVIDVSHVLPRQTILDVNLKGTQNILEACVEASVPAFIYCSTVDVAGPNSYKKIILNGHEEEHHESTWSDAYPYSKRMAEKAVLAANGSILKNGGTLHTCALRPMYIYGERSPFLSVMILAALKNKGILNVTGKFSIANPVYVGNVAWAHILAARGLRDPKKSQNVQGQFYYISDDTPHQSYDDLNCTLSKEWGLRLDSSWSLPLPLLYWLAFLLETVSFLLRPFYNYRPPFNCHLVTLSNSKFTFSYKKAQRDLGYVPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ
What is the function of this protein?
A bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo-Delta(4)-steroids, an essential step in steroid hormone biosynthesis.  Specifically catalyzes the conversion of pregnenolone to progesterone, dehydroepiandrosterone (DHEA) to 4-androstenedione, and androstenediol to testosterone (PubMed:1537836, PubMed:1985917).  Additionally, catalyzes the interconversion between 3beta-hydroxy and 3-oxo-5alpha-androstane steroids controlling the bioavalability of the active forms.  Specifically converts dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR.  Also converts androstanedione, a precursor of testosterone and estrone, to epiandrosterone (PubMed:1537836).  Expected to use NAD(+) as preferred electron donor for the 3beta-hydroxy-steroid dehydrogenase activity and NADPH for the 3-ketosteroid reductase activity (Probable).
What are the official names of this protein?
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I, 3-beta-HSD I, 3-beta-hydroxy-5-ene steroid dehydrogenase, 3-beta-hydroxy-Delta(5)-steroid dehydrogenase, 3-beta-hydroxysteroid 3-dehydrogenase, Delta-5-3-ketosteroid isomerase, Dihydrotestosterone oxidoreductase, Steroid Delta-isomerase.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Protein: MAGL2_MOUSE
Sequence: MSQLSTNLGDSSPPESPVPAVHSRPTVLMRAPPASSRAPPVPWDPPPVDLQAPMAAWQAPQPAWEAPEGQLPAPVAQLAQPPGLGAPMVQAPPLGGGMAKPPTPGVLMVHQPPPGAPMAQSSTPGVLMLHPSVTGAPLAHPPPPGTPMTHPPGTSMAHPPPPPPPPPPPPPPGTPMTHPPPPGTPMGHHPPPGNPMTHPPPGNPMVHPLTHGAPMVHGGPHGTPMPHVPITGTPIAQQPTPGVLMAQQLTPGVLMVQPPAPGAPMVQPPPQAALMTQPAPSITPMAKPPGPGVVMIHPPGARGPIIQTPVSGAPMAQTVLPPGQPLATWAPQGQPLILQIQSQVIRAPPQVPSVPQAPQVQLATPPGWQATTPNWQVTPQGWPATPLTWQATQVTWQAPTIAWQATQPGRQGHSTIRTGHTPIRPGPAPLLRQIPPMIRQIQPVMRQAPPLIRQVPIRPAPHGIASQPQLWQVLPPPPPLRQAPQARLLLPRVPGTGQVSTVPPVAQIHLVPQSGPQVPQTVLPAQLSIPIPVPQAAAQSAPRTVHCPPIIWQAPKGQAPVPQELPVPQELPVPQELPVPQEVPVPQEIPVPQEIPVPQELPVPQELPVPQELPVPQELPVPQELPVPQELPVPQELPVPQELPVPLEFQEVQQAQAVGWRAPKVPPHFWQPVSAQEAQEQATQIAHVEQQQPFQGAPASSKALQTQLPTHQAQASGLQAELPSVQLQPSWQGPLPMLQAQPGASATLANFPRGSTRSRMAPSGEPGPSSLEPRGPPRERRAPARDKKGPPKERMFIGATFCAPRGASASRAYVPTAWKNLPATSETFPATSRVFPSTSHFQPASSNAFRGPSAASESPKSLPFALQDPYACVEALPAVPWVPYPDGNASSACKSVPAILMVAAAAPQASATAAEASKSSEPPRRPGKATRKKKHLEPKEDNCGHRLSSRDWRGPRTWGNPSHSDWEIQRAMQLLGDRESLYTPQGLNDWGCPNTSRMPRSLEGPSTSRDQEFCGDSGGSQTWMASEVPSVSRGSSAAQEDPDRESQPLSPLDERANALVQFLLVKDQAKVPVQLSEMVNVVIREYKDDSLDIINRANTKLECTFGCQLKEVDTKTHTYIIVNKMAYPQCNLLASYLERPKFSLLMVVLSLIFMKGYCIRENLLFSFLFQLGLDVQETSGLFRITKKLITSVFVRHRYLEYRQIPFTEPAEYELLWGPRAFLETNRVHILRFLAALYENQPQIWSCQYLDSLAELEYKDANAAAEESHDSDDDAHDPTSSPHPH
What is the function of this protein?
Probably enhances ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases, possibly through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.  Acts as a regulator of retrograde transport via its interaction with VPS35.  Recruited to retromer-containing endosomes and promotes the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASHC1 together with TRIM27, leading to promote endosomal F-actin assembly (By similarity).  Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer.  Significantly promotes the cytoplasmic accumulation of CLOCK (PubMed:22208286).
What are the official names of this protein?
MAGE-like protein 2, Protein nS7.
What are the subcellular locations of this protein?
Early endosome. Cytoplasm. Nucleus. Note=Recruited to retromer-containing endosomes via interaction with VPS35. Colocalizes with CLOCK and ARNTL/BMLA1 in the cytoplasm, and with PER2 in the cytoplasm and nucleus.
Protein: PSTS3_MYCBP
Sequence: MKLNRFGAAVGVLAAGALVLSACGNDDNVTGGGATTGQASAKVDCGGKKTLKASGSTAQANAMTRFVNVFEQACPGQTLNYTANGSGAGISEFNGNQTDFGGSDVPLSKDEAAAAQRRCGSPAWNLPVVFGPIAVTYNLNSVSSLNLDGPTLAKIFNGSITQWNNPAIQALNRDFTLPGERIHVVFRSDESGTTDNFQRYLQAASNGAWGKGAGKSFQGGVGEGARGNDGTSAAAKNTPGSITYNEWSFAQAQHLTMANIVTSAGGDPVAITIDSVGQTIAGATISGVGNDLVLDTDSFYRPKRPGSYPIVLATYEIVCSKYPDSQVGTAVKAFLQSTIGAGQSGLGDNGYIPIPDEFKSRLSTAVNAIA
What is the function of this protein?
Functions in inorganic phosphate uptake, is probably the main carrier for phosphate uptake (By similarity).  Part of the ABC transporter complex PstSACB involved in phosphate import (Probable).
What are the official names of this protein?
Phosphate-binding protein PstS3, PstS-3, 38-kDa lipoprotein, P38.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Secreted. Note=Present on the cell surface.
Protein: SYMPK_XENLA
Sequence: MAVSMASQFFSQEEGTSEVVSTSERVVELLNMAALATNDTKITMLKQVQELIINKDPTLLDNFLDEIIAFQADKSVEVRKIVVNFIEEACKLDNELLIKLIANLHMLLKDENVNVVKKSILTMTQLYKVALQWVARSRPPSEQQESCWDLVTEMAADILLLLESDNDGMRTHAVKFVESLIVTLSPRTADSEVPKRQDGDISLEQIPPDHQFLKYNTLRDLGKQAVKELLKFMAHPAISSINLTAALGSLASIARQRPMFMAEVIQAYETLHANLPPTLAKSQVSSVRKNLKLQLLSVLRHPSSYEYQGPISTLLLDLGTSQGEITRHLPPPRDSNRKRAREDGEGGQKKSRTDIPLPDDDDDKDTMQLPTIPAPAPSTQSATDITADFVRPLLSPENVANLVLISMVYLPDSMPASFQSTYTPVESAGTDSQIRHLARLMATQMSAAGIGPGVEQSKDIPVDVVEEENIKPEGLVIKRRISALTKGQAISVLGCQSEKTKEEEEEEDDAPLAKKRPEPILPATQIRPSGVGGRKKVFRLKEVTEPLTDVQIKSLKLGAVRRILQAERSVGSSGASQMRVKVLARLVTQLDISVKAEVLSHFLNDPRMRLDLALAWLYQEYCEYQSGAGEEGYQECLIGILTGLQERPDQRDGVFTKVVLEAPLLTDSALDVLRKYCEDEGRSYLGMSTLRDLILTRPARQFQYLHLLLDLSSHEKDKIRQQSLHFIKRMYEKESLRPYIEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEDTVKQCLYLYLALLPQNHKLIHELASVYTEATADIKRTVLRVIETPIRGMGMNSPELLLLVENCPKGAETLVTRCLHILTDKVPPSPELVKRVRELYHKRLPDVRFLIPVLNGLDKKEVIQALPKLIKLNPIVVKEVFNRLLGTQHGEVSSSLSPLTPGDLLVALHNIDSSKCDMKSVIKATNLCFSARSVYTSEVLAVVLQQLMDTTPLPMLLMRTVIQALGMYPRLGGFIMNILTRLIYKQVWKYPKVWEGFIKCCQRTKPQSFSVLLQLPPPQLLSVLQTSPDLRDPLLAHVRAFTPHQLAHVPHSIMAILEAESRTDAGAEEAAQVEEEQETPAQDIIARRLAQEKSLKKQIEEQKGRNNQEMEEVAEVDPPAIFIAEEEEEESLKSQGKEEPQEDSSSNATTAEKSPVADEPMEEEPVEKKD
What is the function of this protein?
Involved in histone mRNA 3'-end processing (By similarity).  Involved in the cytoplasmic polyadenylation element (CPE)-mediated polyadenylation of maternal mRNAs in maturing oocytes.  Serves as a scaffold upon which cytoplasmic polyadenylation regulatory factors are assembled.
What are the official names of this protein?
Symplekin.
What is the protein family that this protein belongs to?
Belongs to the Symplekin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Cajal bodies (CBs).
Protein: MDHM_BRANA
Sequence: MFRSALVRSSASAKQSLLRRSFSSGSVPERKVAILGAAGGIGQPLALLMKLNPLVSSLSLYDIANTPGVAADVGHINTRSQVVGYMGDDNLAKALEGADLVIIPAGVPRKPGMTRDDLFNINAGIVKNLWSAIAKYCPHALVNMISNPVNSTVPIAAEIFKKAGMYDEKKLFGVTTLDVVRVKTSYAGKANVPVAEVNVPAIVGHAGVTILPLFSQATPQAILSGDALTVTTKRTQDGGTEVEEAKAGKGSATLSMAYAGALFADACLKGLNGVPDVVECSYVQSTITELPFFASKVRLGKNGVEEVLDLGPLSDFEKEGLEALRPGIKSTIEKGVKFANQ
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CRCB2_STRR6
Sequence: MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNYLGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLVLYLLLSIGGGLLLAYFLGRKKW
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: G3PC_CHOCR
Sequence: MTAPKVGINGFGRIGRLVLRAAIEKGTCQVVAINDPFIDLDYMAYMLKYDSTHGRYAGDVSIKDGKLQVDGNSITVFAHRDPAEIPWATAAADYIVEATGVFTLKDKAAAHFKGGAKKVVISAPSKDAPMFVCGVNEAKYTPDLDIISNASCTTNCLAPLVKVIHEKYGIEEGLMTTVHATTATQKTVDGPSNKDWRGGRGRGRNIIPSSTGAAKAVGKVMPELNGKLTGMAFRVPTPDVSVVDLTVRLASETTYEDIKATMKAAADDSMKGIMKYTEDAVVSTDFIHDDASCIFDASAGIMLNSKFCKLVAWYDNEWGYSNRVVDLIAHISKVQ
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIB_CONGE
Sequence: MGMRMMFTVFLLVVLATTVVSFPSERASDGRDDTAKDEGSDMEKLVEKKECCNPACGRHYSCKGGR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  Both the globular (with C1-C3; C2-C4 disulfide pattern) and ribbon (C1-C4; C2-C3) isomers reversibly inhibit human muscle-type alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE nAChRs (IC(50)=116 nM and IC(50)=643 nM, respectively) (PubMed:34062129).  Both isomers also inhibit alpha-7/CHRNA7 and alpha-9-alpha-10/CHRNA9-CHRNA10 (IC(50)=1113 nM by globular isomer) nAChRs (PubMed:34062129).
What are the official names of this protein?
Alpha-conotoxin GIB.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MENG_HALH5
Sequence: MTETKEERVHQVFEKIYKRYDVMNSVISFQRHKAWRKDTMKRMNVQEGQSALDVCCGTADWAIALGKAVGPTGHVEGLDFSENMLSIGKKKIADERLDHVFLRHGNAMELPYADDTFDFVTIGFGLRNVPDYMQVLREMARVTKPGGKVVCLETSQPTIPVFKQLYFFYFRHVMPLFGKMFAKSYDEYSWLQESTLSFPGRDRLAQMFKEVGLTDVQVKPYSGGAAAMHLGVKESYDEESRNVTC
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PSBH_STIHE
Sequence: MATAKSNSSTPDIEFQPGISTPLGRLLKPLNSEAGKVLPGWGTTVLMGVFMALFAVFLVILLEIYNSSVILDGVTMSWESLGK
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ATP6_LISMF
Sequence: MEEEFPTISLLGIDFNLSNILMITVTCVIVLLIAIICTRNLQRRPTGKQNFIEWVMDFVRGIINSNMDWKTGGRFHVLGITLLMFIFVANMLGLPFQIAINDEVWWRSPTADPIVTLTLAIMVLGLTHYYGIKMRGFKHYFVGTYFSPMKFLFPLKLVEEFANTLTLGLRLYGNIFAGEVLLTIIATQLAHMNIFVGVLAIIPALLWQGFSIFIGAIQAYIFTMLTMVYMSHKVSDEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSP3_GLORO
Sequence: MAQLPPEDIATMPAQKVVFNAPFDNKATYYVRIINPGTKRIGFAFKTTKPKRINMNPPNGVLGPKESVNVAISCDAFDPSSEDSKGDRVTVEWCNTPDPAAAAFKLEWFQGDGMVRRKNLPIEYNV
What is the function of this protein?
Central component in molecular interactions underlying sperm crawling.  Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod (By similarity).
What are the official names of this protein?
Major sperm protein 3.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasm, cytoskeleton.
Protein: MURC_FRATW
Sequence: MNKKILFLGVGGIGVSALAIAAKRLGAHVAGYDSVANKLTAKLEALGIVIFTSPNGVDVANFDIVVYSSAILSSHPLLSQARSLGIQCLQRAMFLAVLMKDFSYSIAITGTHGKTTTSSVLATLLCQLDKYSSFIVGGVVKYADSNIQVNGTDKLVIEADESDASFLFLSPQVVIITNIDLDHMATYNNSYQTLLENFTDFVSKESVKSIYLCVDDQGCRDLLAKYNQSDKNVTSYGFSINADVQIYDYHIIDEITHFKIRYKGDDLSFKLQLPGRYNVQNATACIIACLDLGFKYEDIRNALIKVTGVARRFDLYTKVISGHQVTVIDDYGHHPVEVANSISAVRDRYPNKKIIHVFQPHRYTRNRDLIKDWPKALSLADQLILLPTYSADEQIIKGAESQDIVKGLSGYLLADGFDHAIYFLEKLANENTVILIQGAGDVTNLVEILSE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTRC_HUMAN
Sequence: MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
What is the function of this protein?
Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors.  Has chymotrypsin-type protease activity and hypocalcemic activity.
What are the official names of this protein?
Chymotrypsin-C, Caldecrin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Elastase subfamily.
Protein: UREE_TRIV2
Sequence: MLTLTQLVTPNPNLAVTLTLPLTAEERCRSRHRFEIEDGQVVFLRLPRGTVLQDGDILQDETNGNLIRIVAKPEPVLTAVAQTQLLLMRAAYHLGNRHVPVEITPTYLRLSPDTVLRTMLEHMGLEITAEILPFQPELGAYGHNHPH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENCAP_BACTR
Sequence: MNKSQLYPDSPLTDQDFNQLDQTVIEAARRQLVGRRFIELYGPLGRGMQSVFNDIFMESHEAKMDFQGSFDTEVESSRRVNYTIPMLYKDFVLYWRDLEQSKALDIPIDFSVAANAARDVAFLEDQMIFHGSKEFDIPGLMNVKGRLTHLIGNWYESGNAFQDIVEARNKLLEMNHNGPYALVLSPELYSLLHRVHKDTNVLEIEHVRELITAGVFQSPVLKGKSGVIVNTGRNNLDLAISEDFETAYLGEEGMNHPFRVYETVVLRIKRPAAICTLIDPEE
What is the function of this protein?
Shell component of a type 1 encapsulin nanocompartment.  Assembles into proteinaceous icosahedral shells 42-43 nm in diameter with an iron- and phosphorus-rich core (1Fe:1. 1P) which can store over 23,000-35,000 iron atoms (with a calculated maximum of 83,000 Fe).  There are 2 types of negatively charged open pores in the cryo-electron structure; a 3-fold pore where 3 hexamers meet with a minimal size of 7. 2 Angstroms and a 5-fold pore where pentamers meet with a minimal size of 2. 3 Angstroms.  The 2-fold pore seen in other encapsulin nanocompartments is closed.  Empty compartments can be generated in E. coli (PubMed:28263314, PubMed:31282860, PubMed:31194509).  Both types of pore have extra density in their centers in the structure (PubMed:31282860).  2 different cargo proteins have been identified (IMEF and Fer); when both are expressed in E. coli with the shell protein only IMEF is detected within the nanocompartment.  E. coli expressing all 3 genes stores the largest amount of iron and is protected from Fe/H2O2-induced oxidative stress (PubMed:28263314).  Part of the iron-mineralizing encapsulin-associated Firmicute (IMEF) system (Probable).
What are the official names of this protein?
Type 1 encapsulin shell protein, IMEF encapsulin.
What is the protein family that this protein belongs to?
Belongs to the encapsulin family. Family 1 subfamily.
Protein: HIS7_PSEFS
Sequence: MAERKASVERDTLETQIKASINLDGTGKARFDIGVPFLEHMLDQIARHGLIDLDIVSKGDLHIDDHHTVEDVGITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLQMHVPYTRATVGGFDVDLFQEFFQGFVNHALVSLHIDNLRGTNTHHQIETVFKAFGRALRMAVELDDRMAGQMPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NET5_RAT
Sequence: MADYRTLFSPSGTGSAVTVLVALSLLLLLSQATSDPCYDPGGRPRFCLPPVTQLVGKAAAPCSQTCALPADSPDPVCNGTLTLDLDGSFLLTSVTLRFCTAGPPALVLSAAWAIGGPWRPLWRRPAWPGVLGGPKKVTFHSPPGPKTRIVASYLRVELGGKAGLVTTGVRGRCQCHGHAARCAARAQPPRCRCRHHTTGPGCESCRPSHRDWPWRPATPQHPHPCLPCQCHPIGATGGMCNQTSGQCSCKLGVTGLTCNHCGPGYQQSRSPRMPCQRIPEATTALATTPVASRSDPQCQGYCNVSVSSVHMNLQKYCQQDYVLHARVAESAQVSASSSLSSLSEAVGPEWWRLAVHVLAVFKQRAWPVRRGSQEAWVPRADLSCGCLRLRPGADYLLLGRAAENHTDPAHLILNRHSLALPWRPRWAGPLRRLQQKERGGACRGLLPPTRSPGPRN
What is the function of this protein?
Plays a role in neurogenesis.  Prevents motor neuron cell body migration out of the neural tube.
What are the official names of this protein?
Netrin-5, Netrin-1-like protein.
What are the subcellular locations of this protein?
Secreted.
Protein: GH39_ORYSJ
Sequence: MFVKSETKTRGGLTAWFALTSVYKSEQFKSMAIAYTSPTAAILCEDAFQSMYAQMVCGLCQRHDVVRFGAVFAAALVRAIRFLQLNWGQLAADIEAGELGPHVADPSVREAVSGILRSDAELAEFVRIECSKGDWAGIITRIWPNTKYVDAIVTGAMAQYIRTLQYYSGGLPIVSTSYASSECFFGINLRPVCDPSEVSYTIMPNTAYFEFLPVGEVVDATNLVDLARVEVGREYEVVITTYAGLSRYRVGDVLRVTGFHNAAPQFRFVRRQSVLLSVELDKTDEAELHRAVERASSALLRPRGVSVAEYTSRACTERIPGHYVVYWELLTESPVGAGDGDTVDGETLGRCCLEMEEALSAVYRQGRVADGSIGPLEIRIVRPGTFEEVMDLAVSRGTSIGQYKVPQCVTVPSVVELLDSRVVSSQFSPALPHWIPTPRSD
What is the function of this protein?
May catalyze the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin.
What are the official names of this protein?
Probable indole-3-acetic acid-amido synthetase GH3.9, Auxin-responsive GH3-like protein 9, OsGH3-9.
What is the protein family that this protein belongs to?
Belongs to the IAA-amido conjugating enzyme family.
Protein: ACCD_LISIN
Sequence: MLGDLFTKPKKRKYATIPSDGTKADVPEGIMTKCPECKKIMYTKELQKNLMVCNYCGFHHPIGATARIDMLVDEGSFEELDANLTTANPLGFENYMDRIEKDKQKSGLNEAIVTGHATIDGNPLVIAVMDSRFRMASMGSVVGEKILRGVEEADKTNKPFVIFTASGGARMQEGMLSLMQMAKTSAAFKRFSNHGGLVITVMTHPTTGGVSASFASLGDYNFAEPGALIGFAGRRVIEQTVREELPEDFQTAEFLLKHGQLDDCISRLDLKNKLSFILKIHVKTPEAGGESDGE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_TROW8
Sequence: MGESITAPEVRLINSDGGPLGVVSRSVALRLAGEVGLDLVEVSPFSKPPVVKIMDYGKFRYEASQKAKEARRRQSGVSVKEVRFRLKICDNDYDVKLRKAISFLQAGDKVKVMILFRGREQSRPELGVKLLKKFADDISEFGSADSLSRTDGRGMAIMVSPIKSKTIVREKSSHAQKGDKQP
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_ECOSM
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFN14_HUMAN
Sequence: MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFEFPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLEACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-14, IFN-alpha-14, Interferon alpha-H, LeIF H, Interferon lambda-2-H.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: YHYD_ANACY
Sequence: MEQLPLPAPIHYELILQLLEKQTMNAVSQNSDLQHQVSQLIVTLRKAASQQKRLEENCQASAVTVDHRWSLNHHGGKVITPD
What are the official names of this protein?
Uncharacterized 9.3 kDa protein in soluble hydrogenase 5'region.
Protein: MAT1_COCEL
Sequence: MDSARAPTEDEIAKFLATRTSSQMLQLMRCIKQPAAQFAFTAKLLTITPVKNTPPTVPEKAKKALNAFVGFRCYYIAIPAFKPWPMKKLSNLISLLWEGDPNKSLWSLMAKAWSNIRDQVGKDQAPLDEFFGIICPHLELPDPAYYLDLHGWSLGVNQEGDPTLLRIIDSKPASIGIGHINLALSVEDIITFVQKAGFAPTYTPDANDTSPTFLGQSLSSTFEVNHPANSIPAASQVDQARVAARNRRRAKRQSARELEFQEKLENDLEFKEKINREMDLVLERTPPAGPDPLPDFDFTPFYEGVNNLICEHMAMEQSNAGYPEGAHLFNDFGIDSSKAYLGMDNFATDMPDLIDYDAFRLGANEDVALPVFDDIAHA
What is the function of this protein?
Required for mating.
What are the official names of this protein?
Mating-type protein MAT-1.
What is the protein family that this protein belongs to?
Belongs to the MATALPHA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3477_ARATH
Sequence: MADILRQLLDCGKLSDETCHSILCGLGQHVDALHLSKTEEEVDGWTSEEDEELDQEYCRQVTESLGFDIDGKVCIPACGISPVFLGANKNPRSEVALYGRLGVHCFNIDKERKFQYMRIPKYNVQYPEAMSFHITVEVNDLADNSAHTLQNLVTRSFSRNGEDLRVSTGICRIKPKTPEREICLVDEEAIDKFYRGVMPNFVSKLGADDDKLRFYEVQEQDVCANDWLRLYTEFALFSYWRYNEDGFESCLPVEIKKIIVETCDTHREPRMKLKSSNAIFHINFNAKSCDYKSVSRRTTDGKPGHIVLEINTWKLSST
What are the official names of this protein?
UPF0725 protein At3g44770.
What is the protein family that this protein belongs to?
Belongs to the UPF0725 (EMB2204) family.
Protein: PYRD_PROMH
Sequence: MYYSLVRKALFRLDPERAHDFTFRQLKRLSHSPFQFLIQQSLPAKPVSCMGLSFKNPLGLAAGLDKNGDCIDALGAMGFGFIEVGTVTPRAQVGNDKPRLFRLVEAEGLINRMGFNNLGVDNLIENVKQSQYGGVLGINIGKNKDTPVEQGKDDYLICMEKVYPYAGYIAINISSPNTPGLRTLQYGEALDDLLSAIKNKQLELQGKYQKYVPVAVKIAPDLTHEELIQVADSLVRHHIDGVIATNTTLDKSLVSGLDHCNEAGGLSGRPVQSKSTQIIRQLNEELKGALPIIGVGGIDSLTAAREKMDAGASLIQVYSGFIYHGPALIKSIINHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.