PharMolix/UniProtQA huggingface dataset:
Protein: ISPD_RHOOB
Sequence: MAEGRGPVVALVPAAGQGVRLGENKPKAFVDLGGTTMLTRAVDGLLQSGAVDRVVVIVPEELVESTRSLLPGHVTVVAGGSERTGSVRAGLAVADDAEYVLVHDAARALTPPSLIARVVAELRCGRRAVIPVLPVADTIKTVDVLGAVTGTPERSELRAVQTPQGFTAELLRRAYAAADGIATDDAGLVERLGERVRSIVGEPTAFKITTPLDLVLARALVEEGAH
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: MCR1_ASHGO
Sequence: MLSRITRSSKALNFALGTTAVAAAGYLYAQSRGNLSTSLNKGDVTGQAAAQTFTGDGQWHALKIAKIEQVSHDTRRFTFALPSQDHVTGLTTASALLAKYVTPKGSNVIRPYTPVSDNMARGMFQLVIKHYDGGKFTTHLFGLKENDTVEFKGPIQKWRWDPNMFDSIVLMGAGTGITPLFQMMHHIAENPTDNTKVHLLYGNKTPQDILLRKELEELASKYPDQVKVTYFVDKPEGDYKGEKGFITKDFLKQNLPTPGSNSHIFVCGPPPFMDAFSGNKVSPSDQGQVTGVLSELGYTKDHVYKF
What is the function of this protein?
May mediate the reduction of outer membrane cytochrome b5.
What are the official names of this protein?
NADH-cytochrome b5 reductase 2, Mitochondrial cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: TAL_CHLFF
Sequence: MSSQFEQLKLLSVLVCDTGDPELVKSSGSQDATTNPSLILKVAQEPKYQEMLTEAIAWGIRQNGDDVQTLTFVLDKIQVNFGLEILKCIPGRVSLEIDARLSFNTEAMVQRAIFLSELFVASGGDKKRLLVKIPGTWEGIQAVEILEKQGISCNVTLIFNLIQAIAAAKAKATLISPFVGRIYDWWIAAYGDEGYSIDTDPGVASVSNIYTYYKKFDIPTQIMAASFRSKEQVLALAGCDLLTVSPKLLDELKKDQSSVTKKLDVAEAKKLDVQPVELTESVFRFLMNEDAMATEKLAEGIRIFSGDTQILEAAVTEFIKQIAAQDA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_CENSY
Sequence: MSVRFQSDDEYMRNLITTSGISIGTQVKTKFMKQFISDTDPTGTYTLDLEATQGRIKAAAQFIEHTGASELIVCSGKDSARVPIRKFAELVGCKDIHKRFMPGTLTNPDLPKYMEPKLLLVCDPQVDAQAVTEATNAGIPVIGIANSDNVTSRLDVIIPANNRGRGALAAIFWLLAREVLVIRGEVDETKPMKYEIDDFETKDVREDE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SURE_PSYCK
Sequence: MKILMSNDDGVYAPGLLALYEALSTMAEVMVVAPNSEQSGCASALSITTPLYTHQLPSGFIAVNGTPADCIYLALNEIYSDTDFDCVITGINSGANLGQDVLFSGTFGAALTAQLFGIPAIATSLVGGGAKSSEQECERHYQMAASEIVKLLTDTPILDICKNLPYHVLNVNIPDVSNADEINGRKMTVLGHRKIARPVHHVVDPRGRDAYWLSLRKRQDIWADNTDHVSSGTTMTDDQAVAAGYISLSPVRLHHTPAATLDMLSALML
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_I75A0
Sequence: MDSNTVSSFQDILLRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHLLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: FMT_NEIMA
Sequence: MKVIFAGTPDFAAAALKAVAAAGFEIPLVLTQPDRPKGRGMQLTAPPVKQAALELGLRVEQPEKLRNNAEALQMLKEVEADVMVVAAYGLILPQEVLDTPKHGCLNIHASLLPRWRGAAPIQRAIEAGDAETGVCIMQMDIGLDTGDVVSEHRYAIQPTDTANEVHDALMEIGAAAVVADLQQLQSKGRLNAVKQPEEGVTYAQKLSKEEARIDWSKSAAVIERKIRAFNPVPAAWVEYQGKPMKIRRAEVVAQQGAAGEVLSCSADGLVVACGENALKITELQPAGGRRMNIAAFAAGRHIEAGTKL
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SECA_PSEA6
Sequence: MFSSILTKVFGSRNDRTLKKLNKITEQVNQLEAQYEALSDEQLKAKTGEFQKRLQDGEDTDNLLPEAFAVVREASKRVFSMRHFDVQMLGGQVLHTGQIAEMRTGEGKTLTSTLPAYLNALSGKGVHVITVNDYLASRDAEGSRPLFEFLGLSVGCNIPGMNHAQKKEAYAADITYGTNNEFGFDYLRDNMAFSPGDRVQRELHYAIIDEVDSILIDEARTPLIISGQAEDSSELYRKINAIIPQLEQQEKEDEEGKNGDGDYTIDEKGKQVHLTEKGQIHVEEILKTSGILGEDESLFAAANISLLHHVNAALRAHKLFSRDVDYIVKGDDVVIVDEHTGRTMEGRRWSEGLHQAVEAKEGVNIQNENQTLASITFQNYFRLYDKLAGMTGTADTEAFEFQSIYGLDTVVIPTNKPMVRKDKADLIYLTAQEKYEAIVEDIKDCVKRGQPTLVGTVSIENSELISNILKKAKIPHKVLNAKFHEQEADIVAQAGKPGAVTIATNMAGRGTDIVLGGNWQVAVDGINDPKPGTVEKIKEQWQKDHDAVIEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSLDDALMRIFASEKMGNMMKRLGMERGEAIEHPWVTRAIENAQRKVEGRNFDMRKQLLEFDDVANDQRKVIYEQRNELLDEGDIYSTIEAIRIDVVDSIISQYIPPQSLSEMWNVSGLEEHFKSEFLLDIPLQKWIDEDDKLYEEKIRERILEEVNNAYKAKEDIVGPDVLRQFEKAVMLQNLDSHWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFTEMLEALKVEVVTVLSKVQVKAESDVEAVEEQRRQADEQPKQYEHETASATQAPEQAPEAAPAARPGNALRDGPKVGRNDPCPCGSGLKYKQCHGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: SYA_MYCPN
Sequence: MKWTTDKVRQTWLDYFTAKGHLALPSKSLIPVNDPSLLWINSGVATLKDYFSAKKTPPSKRLANAQICLRVNDIENVGFTSRHQTLFEMLGNFSIGDYFKEEAIGFANDLLVNHYHLDPKRFYITVYQDDELTFNTWLKHGIPASRIIKCDRDRNFWDLGLGPCGPCTEIYYDRGERFDPHKVGEKLFFEDIENDRYVEVWNIVFSQFNNDGNGNYSELAQKNIDTGAGIERLVAILQDAPTNFDTDIFLKLIGIIEQHCKHKYDTNLYFKFDQKLNEAQSAFRIISDHFKAITFTIAEGVLPGPNERSYIVRRLLRRALLACKKLDLDLKFIDPMVDAIISVYGSYYQQLQGKNQVVQQAIWKEVTAFDKTINLGLMLFEKSIAHNALQPQVAFQLYETYGFPIEMIKELVDKRQLQVDWKAVEQLMEQHRLISKQNSNTLSFEKQNEHLVNFKTASEFLYEANEITAKVIGLFDEQYQPVQKLHNQSGYVVFDQTVLYATSGGQRYDEGYCINHSQNDQRVSFQGVFKGPNKQHFHFFLTGSFQLGDKVILVHDGKWRQLVKNNHSLEHLLHAALQNEIDPLIKQDGAFKSAQKATIDFNFSRALTWAELERVEHRIRQIIQQDIQREEIFTDLEGSQKLNAIAYFEEEYSNHELLRVIRFGDFSVELCGGTHVEHTGLIENCFITDYYARGTGRWRIEIISSNETIAAYLNEQNGKLSETINSLHNTLNNIANPALNKQKTALTKQLNHFHLPQVITDLRKCQALLNELKITVNELKTEDFKWKQKQLAEKIKQELLELAKQDKAYVLASFAAVDPKLLSQVAQAVLNQHKNKLFVLLNQFNNSPSFMLLGQDVSKCIQLLKAHFELKGGGSNNFFRGSFNESVDVSKLQAILDTLQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_NITEU
Sequence: MKLKFTKMHGLGNDFIVIDAINQSVSLDPATIRRWADRHFGIGFDQLLVVEKPGESGDFRYRIFNADGGEVEQCGNGARCFARFVRDHDLTRKNTIRVETACGIIMPTVEENGEVSVDMGIPRFDPARIPFITQERALTYPLNVNDREIEISAVSMGNPHAVQIVPDIDLAPVTSEGPAIESHPFFPEKVNAGYMQIVDRTHIRLRVFERGTGETLACGTGACAAVVSGISRGLLDSEVQVTMRGGNLRIRWEGEDQPVWMTGPAVSVFEGTIDL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL023_HUMAN
Sequence: MSFSPYSTMITVCVCFNSRVQLTVPSFTAWLRSRYSKALFMVLRRAAQEKDKGVCQGWHCVKKWACKGRIPGQPLQPQPLGPYLRSLSQHPATQTPRPQARASSRYLELHRSQNRGGSEFKFWFCYCLIACCRDSISSSGKWE
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00173.
Protein: ACCA_CROS8
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFNMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSVIPEPLGGAHRNPEAMAQSLKTQLLADLADLDVLSKDDLLNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCA11_CAEBR
Sequence: MYAKKFTGSDPQTVRTAAEIVALQRMKNRNDSDTDFSDDDEETSGGCPKMTPQEEQRMFEREQQIAFSGRCTIGDPESCHQLRTDINHRCGPRPSTSSNATWNILNRDVQRRNGPVMTSASRAHLLNTHLPNKKRRVDQLRTKNFCAQYIQNGRKMVVSSQGERENSFLSTKSGKIEISLPILSMQRTPCGPLQLVDLDTAVNQQGDLISYCTWKDAVYIGRMEQEDNQNITWFPIDWHGEHAVQNQCAVFCVRFSDDSEQIVCGTSEYSIHVFDVEQRRRIRTIVNAHEDDVNSVCFADYGSNLIYSAGDDGLVKVWDKRAWSDGDVIPVGVFAGHRDGVTYVDSRQDERYLLSNSKDQTIKVWDLRKFSCQGGVEATRACVQSQHWDYRWQPAPPGLCQPVQGDTSVMTLRGHSVLHTLVRAKFSPENTGRRFIYTGCARGEIVVYDIVTGTVSRRLKGHQAVVRECDWHPQENEIVSTSWDGVTTVWTWDERAEGVIAPYDHPNIHQFGDEDSCDELYQPIKKPQRKLRKPISARNAKCPTTSSEPDDFQI
What is the function of this protein?
Involved in regulation of lifespan.  Required for dopaminergic CEP neuron degeneration in response to Mn(2+).
What are the official names of this protein?
DDB1- and CUL4-associated factor 11 homolog, WD repeat-containing protein 23.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LEC14B family.
Protein: QOX2_STAA3
Sequence: MSKFKSLLLLFGTLILLSGCSNIEIFNAKGPVASSQKFLILYSIVFMLVICFVVLGMFAIFIYKYSYNKNAESGKMHHNAIIETIWFVIPIIIVAALAIPTVKTLYDYEKPPKSEKDPMVVYAVSAGYKWFFAYPDEHIETVNTLTIPKDRPVVFKLQAMDTMTSFWIPQLGGQKYAMTGMTMNWTLEASQTGTFRGRNSNFNGEGFSRQTFKVNAVSQKDYDKWVKEVKGKKTLDQDTFDKQLLPSTPNKALEFNGTHMAFVDPAADPEYIFYAYKRFNFELKDPNFTSEENMFKDVSDKPLIPARKAQITNANYKRHGMKLMILGNDEPYNNEFKKDESKNAKEMKKISKDAQDQDNDDHGGGH
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.  Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I (By similarity).
What are the official names of this protein?
Probable quinol oxidase subunit 2, Quinol oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3288_ARATH
Sequence: MKYKRKLSLSVVFLFVFYLAAVTSDLESDRRALLAVRNSVRGRPLLWNMSASSPCNWHGVHCDAGRVTALRLPGSGLFGSLPIGGIGNLTQLKTLSLRFNSLSGPIPSDFSNLVLLRYLYLQGNAFSGEIPSLLFTLPSIIRINLGENKFSGRIPDNVNSATRLVTLYLERNQLSGPIPEITLPLQQFNVSSNQLNGSIPSSLSSWPRTAFEGNTLCGKPLDTCEAESPNGGDAGGPNTPPEKKDSDKLSAGAIVGIVIGCVVGLLLLLLILFCLCRKRKKEENVPSRNVEAPVAAATSSAAIPKETVVVVPPAKATGSESGAVNKDLTFFVKSFGEFDLDGLLKASAEVLGKGTVGSSYKASFEHGLVVAVKRLRDVVVPEKEFRERLHVLGSMSHANLVTLIAYYFSRDEKLLVFEYMSKGSLSAILHGNKGNGRTPLNWETRAGIALGAARAISYLHSRDGTTSHGNIKSSNILLSDSYEAKVSDYGLAPIISSTSAPNRIDGYRAPEITDARKISQKADVYSFGVLILELLTGKSPTHQQLNEEGVDLPRWVQSVTEQQTPSDVLDPELTRYQPEGNENIIRLLKIGMSCTAQFPDSRPSMAEVTRLIEEVSHSSGSPNPVSD
What are the official names of this protein?
Probable inactive receptor kinase At3g02880.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: URK_BORGP
Sequence: MAKIIGISGGSGSGKTTVVSKISEFIPEFVLISQDNYYKSVGDYEYEFSKVNFDHPDAFDNNLFYEHLKNLKKNSPIDMPLYDFINHKRQLKTVMVVPTPVIIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLKRDISKRGRTLESVIDQYLNTTRWGYYRFIEPTKEYADLIIPEGGHNDKALYVLSTFLKSLSKEGLDFV
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_CAMJE
Sequence: MMQNIHFIGIGGIGISALARFLREKGFKISGSDLKESKITKELEKEGVKVSIPHHKDNILNKDLVIYSAAIKEENPEFKYAKELGIKCLSRKEALPLILEDKRVFAVAGAHGKSTTSSILASLLDDASVIIGAILKEFGSNMIYKESQNLVFEADESDSSFLNSNPYLAIVTNAEAEHLDHYGNEVSKLHHAYTQFLDVAKIRVINAEDEFLKNYKNESIKLYPSKDIKNCTMCIENFKPFTSFELKDLGEFKVFGMGYHLALDASLAILAALNFLDIETIRTRLKNYQGIKKRFDILHADENLVLIDDYGHHPTEIKATLSAAQEYVKLGGYKKITAIFEPHRYTRLATNLKEFAKAFEGVDELVILPVYAAGEEPIELDLKAVFPKALFVEDIKREGKFLVASKGQVFEEGLIIGFGAGDISNKLRQKNE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCCA_ECOLI
Sequence: MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTVLMLPSPGLILTLVGMYGLMFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYLSAGMGDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPALHLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASRD
What is the function of this protein?
Negatively modulates the activity of the FtsH protease for membrane substrates.  Overexpression or stabilizing YccA counteracts the FtsH-mediated degradation of SecY when the SecYEG preprotein translocator is jammed.
What are the official names of this protein?
Modulator of FtsH protease YccA.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=There are conflicting results regarding the localization of the C- terminus of this protein: According to a report, the C-terminus localizes in the periplasm (PubMed:10357810). Another report gives the C-terminus in the cytoplasm (PubMed:15919996). We show the periplasmic location.
Protein: TBP_BOMMO
Sequence: MDHMLPSPYNIPGIGTPLHQPEEDQQILPNAMQQQQLQQQQSQAQPSLAALGSSPIVGFGAIMGTPQRSMHTYAPTASYATPQQMMQPQTPQNMMSPMIAAGNLSSQQMLSQASPAPMTPLTPLSADPGILPQLQNIVSTVNLDCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEDSRLAARKYARIIQKLGFTAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHGQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVREEIYEAFDNIYPILKSFKKQ
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAH_PSEP5
Sequence: MKTRVTRLTVAAPNDVSALAQAIESGEVDPTRVIAVLGKTEGNGCVNDFTRAFATSTLKRFFAERLALNETEVDERIAFVMSGGTEGGLSPHWLVFEVDDSAPSRDTTTPGLAAGVAFTRDLRPEEIGRTSQVELTRDAVLRAMAAAGIQRVEDVHFVQIKCPLLTAARINEAAARGQSVACHDTYESMGYSRGASALGVAAALGDLPGDVRDEQICREWSLYSSRASSSAGIELLRNEVLVLGNAPGWDPEYRIGHAVMEDALDAQAIERALASVPGGDKIKLTPERLAGLLVKAEPSASGSIRGNRHVMSDDSDINGSRHARALVGGVLAGQLGDTRLFVSGGAEHQGPNGGGPLALIVRS
What is the function of this protein?
Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine.  Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.
What are the official names of this protein?
Cyanuric acid amidohydrolase, CAH.
What is the protein family that this protein belongs to?
Belongs to the cyclic amide hydrolase (CyAH) family.
Protein: DAPA_ECO5E
Sequence: MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1767_STAAS
Sequence: MNALFIIIFMIVVGAIIGGITNVIAIRMLFHPFKPYYIFKFRVPFTPGLIPKRREEIATKIGQVIEEHLLTETLINEKLKSEQSQQAIESMIQQQLQKLTKDQLSIKQITSQIDIDLEQVLQTNGNQYIESQLNNYYTKHQNQTIASLLPNQLVTFLDQHVDNATDLLCDRARNYLSSAKGTQDINDMLDTFFNEKGKLFGMLQMFMTKESIADRIQQELIRLTSHPKARTIVTSLITNEYQTFKDKPLNELLDASQFNEIAENLSVYVTTYASKQANKPVVTLMPQFVDYLEGQLSSKLANLIIEKLSIHLSTIMKKVDLRGLIEEQINTFDLDYIEKLIIEIANKELKLIMSLGFILGGIIGFFQGLVAIFV
What are the official names of this protein?
UPF0754 membrane protein SAS1767.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SWM2_YEAS2
Sequence: MIDLYNYSNLEGLLDGLTDLNRIPKEYSAVLEPYFQNIARNAHLKSRALKICRSNFHKWNEEGAKTVNPEIIRRCLNLWYVLKGKEYKKLKDPPPADNIIKDEIDVSYVKNLNVVRLEFDEFGKLISNPLENLILEEVEVNDFIQE
What are the official names of this protein?
Nucleolar protein SWM2, Synthetic With MUD2-delta protein 2.
What is the protein family that this protein belongs to?
Belongs to the SWM2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PSRP_PSEPG
Sequence: MKRTAFFISDGTGITAETLGQSLLAQFESIPFNKFTRPYIDSPDKARTMVQQINAAAERDGVRPIIFDTIVNQDIREILATSNGFMIDIFSSFLSPLEQELTAHSSYSVGKSHSIGGNSNYMERIEAVNFALDNDDGARTHYYDKADLILVGVSRCGKTPTCLYMAMQFGIRAANYPLTEDDMERLQLPAVLKKHHNKLFGLTIDPDRLTAIRHERKPNSRYSSFAQCEFEVREVESLFRRENIPNINSTHFSVEEISAKILVEKGVERRFK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: PRND_BOVIN
Sequence: MRKHLGGCWLAIVCILLFSQLCSVKARGIKHRIKWNRKVLPSTSQVTEARTAEIRPGAFIKQGRKLDIDFGVEGNRYYEANYWQFPDGIHYNGCSKANVTKEKFITSCINATQAANQEELSREKQDNKLYQRVLWQLIRELCSTKHCDFWLERGAGLRVTLDQPMMLCLLVFIWFIVK
What is the function of this protein?
Required for normal acrosome reaction and for normal male fertility (By similarity).  Can bind Cu(2+) (By similarity).
What are the official names of this protein?
Prion-like protein doppel, PrPLP.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: INVS_CHICK
Sequence: MNISANCLFSGSSLASEVHAAAVNGDKSTLLKLIAGNSELKDKEDQFGRTPLMYCVLADRVDCAEALLKAGADVNRADRSRRTALHLAAQKGNYRFMKLLLARRGNWMQKDLEGMTPLHLTTRHKSPKCLALLLKHMAPGEVDTQDRNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDIEGKIPLHWAANNKDPSAIHTVKCILEAAPTESLLNWQDYEGRTPLHFAVADGNVAVVDVLTSYEGCNVTSYDNLFRTPLHWAALLGHAQIVHLLLERNKFGTIPSDSQGATPLHYAAQSNFAETVEVFLKHPSVKDDSDLEGRTSFMWAAGKGSDNVIRTMLDLKLDIDINMTDKYAGTALHAAALSGHVSTVKLLLERNAQVDALDVMKHTPLFRACEMGHKEVIQTLIKGGARVDLVDQDGHSPLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMVVLLENNADPNIQDKEGRTALHWLCNNGYLDAIKLLLGFDAFPNHMENSEERYTPLDYALLGEHHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFQERKNLLMKHEQLRKDAAAKKREEESKRKEASLQKGMQNMEQNKFQVQLSTAVREKTASTLQLSNKQTDLQNKRPLSVSASQIQLGRNSRGSPKACRSKGSPKESCLSSELQSEGHNIRQELLRKHIKSKPSCVHFHCGKVKEVTKVEAKHQVAAATELNGEKHKEHAVEANGTSAHGNRRHASACGTAGAGEKTRDQSLSSSGNRGHCEGTSVVVCNVSCAGGIARNSKRCEAVPKSKRHQQKSRHKEVNYERCSPAGSSRPGSAKVVFVNTRNATVCAIEHANNVGNHELAKKTSPLLSTETESTGTGPRNPAACSALDDSLNLEKTGEVGSRSAGDQLCSVAWQSTNIELIPLEIRMQIIEKERTRKELFRKKNYAATVIQRTWRSYRLRQELSQLLSAKRQRKEDEDKWRQETAAFLIQVAWKKQLNHSPQKSVPSCKSLKSVNKTSSAIKTSKQSILKQIYGRSQEGRVYQPARPPSKLKLSDVQLVSANNLQYVNLLENVGKSKQFSYNMRPSTAAKSKSTRLEH
What is the function of this protein?
Required for normal renal development and establishment of left-right axis.  Probably acts as a molecular switch between different Wnt signaling pathways.  Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled for degradation by the ubiquitin-proteasome.  This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling (By similarity).
What are the official names of this protein?
Inversin.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Associates with the cytoskeleton.
Protein: Y1061_RHIE6
Sequence: MSLSTLKNRRERGFFDGQFLIAMPGMEDRNFARTVIYICAHSDAGAMGFVINRPQSLTFTDVLLHLDMIKQEEPIVLPQRARDFPIQTGGPVESGRGFVLHSDDYASDSSIPVSDDICLTATLDIVRAISKGAGPKRATMLLGYSSWGAGQLENEVANNGWLTCPANEELIFDRSLEDKYERALAGMGVTAAMLSAEAGHA
What are the official names of this protein?
UPF0301 protein RHECIAT_CH0001061.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.