PharMolix/UniProtQA huggingface dataset:
Protein: RECO_HALH5
Sequence: MFHKAEGIVIRTVDYGESNKIVTVFTREYGKIALMARGAKRPKSRLTAVTQLFTYGMMMFQKNAGLGTLTQGEIIQSFREVRNDLFRASYVSYVTDLTNKLTEDEKRNPYLFELLYQTIHYMNEGMDPDVLTRIFEVKMFTVAGIKPELDQCVSCRSTDVPVGFSIKEAGFLCKRCIEKDPHAYKITAQVAKLLRLFYHFDLQRLGTISLKPETKATLKTIIHQYYDEYSGLHLKSRRFLDQLESMGFHDQSTD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: A1OC_LOXRU
Sequence: WIMGHMVNSIAQIDEFVNLGANSIETDVSFDKQANPEYTYHGTPCDCGRDCLHWENFNDFLKGLRKATTPGDSKYHEKLILVVFDLKTGSLYDNQAYDAGTKLAKNLLEHYWNNGNNGGRAYIVLSIPNLNHYKLIAGFKDTLKSEGHEDLLEKVGHDFSGNDDIPDVENAYKKAGVTGHVWQSDGITNCLPRTLKRVRLAIANRDSGSGIINKVYYWTVDKRSTTRDSLDAGVDGIMTNYPDVIADVLSESAYKNKYRIATYEDNPWDTFKA
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LruSicTox-alphaIC1c, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_ERYJA
Sequence: MPHQQMLILFGLLPVATNISTWWNFGSMLLACSSMQVLTGFFLAVHYTANINLAFSSIVHITRDVPYGWMMQNLHAIGASMFFICIYIHIARGLYYGSYLNKKTWLSGTTLLIMLMATAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXILPFGIISLSSLHIMLLHEDGSSNPLGTNSDIDKIPFHPYHTYKDLLMLSLMVLTLLMTVSFLPDIFNDPDNFSKANPLVTPQHIKPEWYFLFAYGILRSVPNKLGGALALAMSIMILLTTPFTHTSTIRSMTFRPIMQLMFWTLVATFVVITWAATKPVEPPFTMISQVASTMYFLFFITNPITGLVENKIMKYN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PPAX_BACSU
Sequence: MSDKQVTTILFDLDGTLINTNELIIASFLHTLEHYYPSKYKREDVLAFIGPSLFDTFSSMDPDKCEDMIAMYRAYNHDMHDSLVTEYETVYETLDALKKAGFTLGIVTTKLRDTVNMGLKLTGIGEFFETVVTLDDVTNAKPDPEPVLLALKQLGSEPAEAIMVGDNYHDVLAGKNAGTKTAGVAWTIKGPEMLAKHEPDFMLEKMSDLLQIVGVK
What is the function of this protein?
Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P.  Might play a role in controlling the intracellular pyrophosphate pool.
What are the official names of this protein?
Pyrophosphatase PpaX.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PpaX family.
Protein: ATG20_YEAS7
Sequence: MSDLNDVQENAKLNSETRNTGKAEPPHGTTEYVAEAEISKNGVGSPKKSPKKGKVGKGDNNKVETELVHTALLEKDNPFMEEGPTGFTKSALLEIPGMRSHKLKNPNEDYEDDSEGLLPLNQESNAETCRTSLSGSINSMNGETSASEEPSVSNRKKSARIHILEAKRVSEGQGRAYIAYVIQFENSTVQRRYSDFESLRSILIRLFPMTLIPPIPEKQSIKNYGKSITGSSSKYLLPSEGSGSVDLSLSVIHASVNNSDEKLIRHRIRMLTEFLNKLLTNEEITKTSIITDFLDPNNHNWHEFVNSSSTFSSLPKSILQCNPLDPTNTTRIHAMLPIPGSSSQLLLNKESSDKKMDKERSKSFTNIEQDYKQYENLLDNGIYKYNRRTTKTYHDLKSDYNEIGEVFAQFAHEQAQVGELAEQLSYLSNAFSGSSISLEKLVGRLYYNINEPLNESVHMATSARELIKYRKLKYLQNEMIKKSLNSKRAQLEKLEAQNNEYKDVDKIIDNEMSKSHTINLERPNNNTGSGGKSYGGKLFNGFNKLASMVKDSVKYQETDPHTASINLKKEIEQLSESLEVTENDLEVISKVIKNDQLPKFSKEREVDLSEILKHYSRYMRNYARQNLEIWKEVKRHQDFA
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Functions in protein retrieval from the endocytic pathway.  Required for proper sorting of the v-SNARE protein SNC1 (By similarity).
What are the official names of this protein?
Autophagy-related protein 20, Cytoplasm to vacuole targeting protein 20, Sorting nexin-42.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: C7113_PRUMU
Sequence: MYSVLVQETPMALLQLLKEHSSLFAFSLLILLLKFIYKDKSRKRRVKLPPSPPKLPVIGNLHQLGNKPHLSLRCLAEKYGPIIYLQLGEIPTVVVSSARLAKEVLKTHDLALSSRPQIFSAKHLFYNCTDVVFSPYGAYWRHIRKICILELLSAKRVQSFSHVREEEVARLVRRVAEFYPGTTNLTKMLGLYANDVLCRVAFGRGFSEGGDYDRHGFQKMLEEYQELLGGFSIGDFFPSMEFIHSLTGMKSRLQETFRRFDELFDQMVTDHLSPKREKEEHKDLVDVLLDIQKKESTEMPLTMDNVKAIILDMFAAGTDTTFITLDWGMTELLMNRKVLERAQAEVRGVVGERRVVLESDLPQLDYMKAVIKEIFRLHPPAPVLVPRESMEDVTIDGYDILAKTRIFVNAWAIGRDPESWEDPEAFEPERFIGSTIDFKGQDFELIPFGAGRRGCPAVTFGTATIELALAQLLHTFDWELPLDTAAKDLDMTEVFGITMHRIANLIVVARPRFP
What are the official names of this protein?
Cytochrome P450 71AP13.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HFQ_GRABC
Sequence: MASEKSQNVQDVFLNHVRKSKTPVTVFLVNGVKLQGIITWFDNFSVLLRRDGHTQLVYKHAISTVMPGAPIQLFDATKPEGDLGRDTAAYSDE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: MSC2_YEAST
Sequence: MNLQELLAKVPLLLSYPTIILSSNLIVPSHNDLISRAASTSAAEYADEKLIFFSTDHAIRLIFLPTFVASSFNLFAHYFNFINYSSRRKYYVLFTAIYFLSILTAIFHPIQSTCITLLIIKLLTTADESSPKIALNFKTILKTFVPFITLTLVILRWDPSFDASSGDVNKISTSLAAYALLILTLRYASPLILSTLSSSIGVVSKDTSVAQHSISRNKRFPLILVLPIFSFVLLYLMTIVNKTYNIQLLMVFVFFGCLSIFFLSLKDLFTEDGNQKKGGQEDEYCRMFDIKYMISYLWLTRFTILLTGIMAIVVHFLSFNEITSSIKTDLLSLLFVVVAEYVSSFSNKQPDSHSHNHAHHHSHLTDSLPLENESMFKQMALNKDTRSIFSFLLLNTAFMFVQLLYSFRSKSLGLLSDSLHMALDCTSLLLGLIAGVLTKKPASDKFPFGLNYLGTLAGFTNGVLLLGIVCGIFVEAIERIFNPIHLHATNELLVVATLGLLVNLVGLFAFDHGAHDHGGTDNENMKGIFLHILADTLGSVGVVISTLLIKLTHWPIFDPIASLLIGSLILLSALPLLKSTSANILLRLDDKKHNLVKSALNQISTTPGITGYTTPRFWPTESGSSGHSHAHTHSHAENHSHEHHHDQKNGSQEHPSLVGYIHVQYVDGENSTIIKKRVEKIFENVSIKAWVQVEPQNSTCWCRATSMNTISANPNSLPLQPIAN
What is the function of this protein?
Probably act as a zinc ion transporter moving zinc from the nucleus/endoplasmic reticulum to the cytoplasm.  Involved in zinc ion homeostasis and cellular distribution.
What are the official names of this protein?
Probable zinc transporter MSC2, Meiotic sister chromatid recombination protein 2.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Protein: PKS1_METAQ
Sequence: MEHVTIKQSGTRADPFRVFIFGDQSSCNLSNLQLLLLKKSNIYLASFVDQVNFTLRHEIARLTTAERQSFPAFSSIQNLVTRALKKDKSVALESTLATIYHLCCFLNYFGDGQEAYPTGPNTHISGLCIGALAAAAVSSSKSLAELVQAGIDAVRVSLKVGLLVARTAALFSHQEPNGTSSSPWSYAVPDSQLPLAFAEEAIESYQVKTKIPPLSLPYISAKGQNSWTVSGPPEIVQHFLESSKFEKTLRLTPLAVHAPYHAPHIFSARDVEHIIHAVGPVSNISSKLSFISSSSSCNLPNGVKFQDLLYRAVEDILILSLDLREAAENIRLVLEATDDVQQCVLFPISTTVCPSLKQSFSPVLASRVSIVDCIMESVAANAGPKSTSGPKPSDSKIAIIGMSGRFPESADVEAFWDLLYQGLDVHRPVPPDRFNGESYYDVTGKRKNTCKVMHGCWINEPGLFDAKFFNISPKEAEQSDPGQRLALATAYEALESAGVVADRTPSTQRDRVGVFYGMTSDDYREVSCGQNVDTYFIPGGNRAFTPGKINYFFKYCGPSVSVDTACSSSLAAIHLACNSIWLNECDTAIAGGTNVMTNPDSFVGLDRGYFLSRTGNCHTFDDEADGYCRADAVGTVILKRLEDAIADHDPILGIISGAYTNHSADSVSITRPHSGAQEEIFSKLLTESGVHPHQVSYIEMHGTGTQAGDATEMTSVLNCFAPSTHPRRLPHESLHLGSTKANVGHAESASGVSALIKVLLMMEKNIIPPHCGIKGKINQKFPTDLDERNVHIAKTATQWNRRDEFNNIRRAFVNNFSAAGGNTALLVEDYPLPTVDSSQEDSRTAHVVAVSAKCVKSLKGNLENLKKFVQKQSSIEGFLPKLSYTTTARRMHHPFRVAIPAASSDQLLSALDQELKHESYRCTSESPVAFVFSGQGSQYSAIGRHLLHFTIFRDEVNSYDILAQRHGFPSIMPLIDGSVDIEDLEPLVVQLGTVCVQMALASLWIAFGMRPAYVVGHSLGHYAALKVAGVLTASDTIYLVAMRARLLQNKCSRGSHTMLAIRSSADEMQAYLDEDIYDIACINGPQDTVVSGCIDDIDRLSQKLMDNRIKVTRVNVPFAFHSAQVDPILDELEAIASQVEFHTPRVAIGCPLLGKTFVAGETSSLGADHIKRHCRETVNFRDILRSAKGDGLISEKTAWIEIGPHTVCSTLLRANINQDIVAVPSLMRNKDGWQVLASSVATLYRHGLPVDWDEYHHDFEACKQVLRLPAYSWDNKVYWIHYVYDWLLTRGDPPVQAAASLPAPPSSFSTASVHRIVHESVDKGKLTLTAECEFTSEQLREVVYGHVVNGNRVCSSSLYTDFGVTLGLYILETYRPDLKDHSVDVQDMVVNKALVHKEGSTMLLRINVILDMTDGKAASMSIYSVNSKGDKTADHAQSSLHFEQPKVWLRNWDSTQYYVERSIEWLKEKADQGLNSRMSSGVIYKLFSSLVDYSTAYKGMQEAIVNTEDFEATALVRFQVDEGNFRCNPMWVDSCGQLAGFLMNGHAKTPKDQVFINHGWQSFRTVRKLSKDKTYRTYVRMRCIEGTTYAGDVYIFDNEGIVGVCGGITFQGIPRKVLNTAMPPPKSQNEAQVHSSPAKSRPKPPGSASSVHSGRLARHTNIEPLKLDAALKSATAARDPMQALFKIVSEEIGIPSASVQNDLVFADYGVDSLLSLSISGRLREELDLDVESSVFETCATLADLATHLGFDTFSSDQSSGQSSSCGGLSPRSDSTGEITSNATTPPSLSPRGSVSGSQCKDVCAILAEEIGVSMSEITNDTDLGELGMDSLMSLAVLSRLREELELDLEGDFFVSHPKFSSFKHMFQQGHEDEIEPEPSAELKQYRATSTLLQGNPKSALYTLFLLPDGSGSSFSYAPINAVRKDVCVYGLNCPWLKSAEKLVQFGLKGLATLYVEEIRRRAPHGPYNLGGWSAGGICAYEAAIQFTREGETVERLILLDSPNPIGLEKLPARLFDFVNGLGLFGDGKAPDWLLAHFLAFIDALDEWKPVPWDKALGSNTPPPMTYILWAEDGICKGTDARPEYRDDDPREMKWLLENRTNFGGNNWDVLLGEPALSIERIQDANHFTMLRKGKNTERVAAFIRSTFG
What is the function of this protein?
Polyketide synthase; part of the Pks1 gene cluster that mediates the biosynthesis of an anthraquinone derivative pigment that contributes to conidial pigmentation that provides protection from UV radiation, heat and cold stress (PubMed:29958281).  The polyketide synthase Pks1 produces 1-acetyl-2,4,6,8-tetrahydroxy-9,10-anthraquinone though condensation of acetyl-CoA with malonyl-CoA (By similarity).  The dehydratase EthD and the laccase Mlac1 further convert the anthraquinone derivative into the final conidial pigment (By similarity).
What are the official names of this protein?
Polyketide synthase 1, Conidial pigment biosynthesis polyketide synthase.
Protein: AROQ_FRATF
Sequence: MDVLVINGPNLNLLGTRQPQFYGHKTLADINNDLLKIAKENNINIDFYQSNHEGQIIDKIQQTAAKIIIINPAAFTHTSVAIRDAFLAINKPFIEIHLSNIYNREEFRTKSFLSDIAYGCIFGFGPNGYTLALIEAINYINMKGE
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: COX5_NEUCR
Sequence: MLRTPTVSALVRNVAVRAAKPTMAVRAASTMPISNPTLANIEKRWEQMPMQEQAELWMALRDRMKGNWADLTLQEKKAAYYIAFGPHGPRALPPPGEQKKVLAYTVAGVFLSFVIFATMRAFAKPPPATMTKEWQEATNEFLKAQKSDPLTGLTSEGYNGKGHVQSPSASA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of Cox2 and heme A of Cox1 to the active site in Cox1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 5, mitochondrial, Cytochrome a-4 protein, Cytochrome c oxidase polypeptide V, Cytochrome c oxidase subunit Cox5a.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase IV family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: YJHV_ECOLI
Sequence: MVGYHQTNQKTDTGKTLTRRPVLVDHNRLPEGSRGRLAVAVAGDHPAAVQVTMTLVNDTGFDPVFSGSIAESWRQQPCTPSYCCDWEAATMLRAFPLAKKGEGRARLPSLYASFGKLGETPTHEDIIDNNRSINWPV
What are the official names of this protein?
Putative protein YjhV.
Protein: UBC14_SCHPO
Sequence: MASASPSSSRRLTKEYSDLREHPIPDIRVNLVDDNLFHWACTALGPSDSVYAGGKFHFSLKFPLDYPFQPPTIEFTTRIYHPNFDSEGNVCLAILKQQVFKPSIKLRSVLEQILQLLREPNPDDPLVASIAEQYRNDRPSFDKIARDYVEQFAKS
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Mediates the selective degradation of short-lived and abnormal proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 14, E2 ubiquitin-conjugating enzyme 14, Ubiquitin carrier protein 14, Ubiquitin-protein ligase 14.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: XPT_LATSS
Sequence: MRLLEERIKKDGQVLGEDVLKVDNFLNHQVDPELMAAMGEEFKRLFEGAPITKILTVESSGIAPAVFSGLAFHVPVVFARKHKSLTLQDNMYSATVYSYTKKVNNHISISKKFLNENDRVLVIDDFLANGQAVEGLLEIIDQAGAQLEGVGIVIEKTFQKGRELLDQRGIHVESLARIAAFEQGEVVFLDENNEN
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_MARMM
Sequence: MSEYQSIGVIGAGAWGTALAQTAAKAGRDVTLWSFENDVAEAVNTKHENTIYLPDVALSTAIVATTSISDLDACDAILAVAPAQHLRRVLEGFLPYARPGLPIVLCAKGIEQSSLSMMTQVLKETIPAALPAVLSGPSFAIDTAQGLPTAVTLACADETVGNALIEALGTSRFRPYLATDLIGAEIGGAVKNVLAIGCGISEGKGLGKSAHAALISRGFAEMTRLALALGAQRETLAGLCGLGDLVLTCSSPQSRNMSCGLALGRGVSLDDIMSGRRAVTEGVASAPAVVELARRHGVEMPICEAVNEILAGRASVDDAIETLLARPFTLETA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_ESCF3
Sequence: MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_BURO0
Sequence: MFGDRQRPMVLVLGLGESGLAIARWCARHGCRLRIADTREAPPNLAALQAEGIDAEFVGGAFTPALLDGGIEIVGLSPGLSPLEPALAALVAAANERGVAVWGELEFFAQALRALGTSGYQPKVLAITGTNGKTTTTSLTGLLCQRSGKKVAVAGNISPAMLDRLASAIDETALPDVWVLELSSFQLETARTFAPDAAAILNITQDHLDWHGSFDAYAQAKGLIFGATTTRVLNRDDAAVMKFAPAAGAADAPRTVTFGLNEPTQDGDYGLSRDNGIAWLVEAVDRDAPDEATTTRRRKRDAAHTPDIAQKRLMPADALRIRGLHNAANALAAFALARAIDLPAAPLLHALREYRGEAHRVEVIATIDDVDYVDDSKGTNVGATVAALDGLAQKIVLIAGGDGKGQDFGPLVAPVARWCRAVMLIGRDAPVIRDTLAETGVPLAGHATLEAAVHAAAELAEPGDAVLLSPACASLDMFRNYAHRAEVFRAAVDAIAIDKGATP
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
Protein: RFC3_BOVIN
Sequence: MSLWVDKYRPCSLGQLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETSSQKDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVCKKEGLNLPPQLAHRLAEKSCRNLRKALLMCEACRVQQYPFTADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMIF
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.
What are the official names of this protein?
Replication factor C subunit 3, Activator 1 38 kDa subunit, A1 38 kDa subunit, Activator 1 subunit 3, Replication factor C 38 kDa subunit, RF-C 38 kDa subunit, RFC38.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AMT2_DICDI
Sequence: MEYLELNGTKEGLSAAVDDMWVLNATYLVFYMQAGFCMLEAGVVRAKNAKSIIMKSIIDTAIGSLLFWALGFGLAFGNADKASNPVIGTSHFFLINYQNLSFFAFQWAFCATSITIVSGSLAERVHVTSCLVYTIVMSAFIYPLSAHWVWSYNGWLRMIGFNGIIDFSGSIVVHIVGGCIGLVGTYLVGPRIGRFDSESGKPKPLPGHSITIYTLGAFIIWYGFYGFNTGSTLGISGGGIAIASRSAVTMTIIACASCATTLLAIKIKSGKYDVVKSVNSLLGGLVSSAAVCSLIDPWAAFIIGCVTSFVYLGCSHLLIKLRIDDPLDSSAIHLGCGIWGALSVGLFSTQENLSLVLKKSTNVYGLFFGGGFEQLGIQLLGIIIVMAWCFFCASILFTILKKFHLLRIEPTKELMGIDIDSAGGPAYQWDN
What is the function of this protein?
Ammonium transporter that mediates the excretion of ammonium from the prestalk cells from the slug.  Controls ammonium homeostasis during growth and development.  Ammonium has been shown to function as a morphogen at multiple steps during the development.
What are the official names of this protein?
Ammonium transporter 2.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Contractile vacuole membrane; Multi-pass membrane protein. Cytoplasmic vesicle, phagosome membrane; Multi-pass membrane protein.
Protein: MBI3_DEBHA
Sequence: MTIRKSNPYLSLVNSYLMDSPQPSSMNYWWNVGSLLGLCLVMQMASGMFLAMHYSSSMELAFNSVEHMMRDVNAGWLMRYIHANGASFFFMCLYLHMGKALYYGSYKSPRVLVWSMGVMMFMLTMATAFMGYCLVYGQMSHWGATVITNLLSAMPFMGGDLVPLSIILSLYLLYISLKTFMKMIFNQSYMCPAKGWVKKVLDNTFCIKKYMHMYLSSRTSPXLYINTMSNMQHMKIMSTKSHTKDRDTSFLEKDIKNMDRNLLALMVGFMDGDGYIRMNKKSKDNMNYIYMSLIMNLNKNDLKLLQYFHQQLNMGKVYNMTPKKGNKLARWEMNKLDLFNKMEPLLEYHNMKFLTETRQKQYLLLKYIKHNKLVYYEDIINNNNYINEFIENNTLMDNFIKLDYFNNWLVGFTMAEGSFLIKKNKDICFQLKQKYNLELFNNMTLFFNTTRKLNINKNKYMQFNVSSKNDIQNMINFFSFSNNQPLLGNKLISYNKWLFTIKNSMRYKELKTPYMSWHQKEQ
What is the function of this protein?
Mitochondrial mRNA maturase required for splicing of intron 3 of the cytochrome b (COB) gene, containing its own coding sequence.
What are the official names of this protein?
Cytochrome b mRNA maturase bI3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LAGLIDADG endonuclease family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DMAW_ARTBC
Sequence: MGSIEIPNCSGSIVYKTISDFIDFPNHEQKLWWHSTAPMFAEMLRVAGYDLHSQYKILGIFLNHVIPFLGVYPTRINNRWLSILTRYGTPFELSLNCSQSLVRYTYEPINSATGTVKDPFNTHSIWDALDRLMPLQKGIDLEFFKHLKQDLTVDDQDSAYLLENNLVGGQIRTQNKLALDLKGGNFVLKTYIYPALKALATGKSIKTLMFDSVYRLCRQNPSLEAPLRALEEYVDSKGPNSTASPRLLSCDLIDPSKSRVKIYILELNVTLEAMEDLWTMGGRLNDASTLAGLEMLRELWDLIKLPPGMREYPEPFLQLGTIPDEQLPLMANYTLHHDQAMPEPQVYFTTFGLNDGRIADGLVTFFERRGWNHMAQTYKDSLRAY
What is the function of this protein?
Tryptophan dimethylallyltransferase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid (PubMed:22403186).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:22403186).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (PubMed:22403186).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:22403186).  Chanoclavine-I aldehyde is the precursor of ergoamides and ergopeptines in Clavicipitaceae, and clavine-type alcaloids such as fumiclavine in Trichocomaceae (PubMed:22403186).  However, the metabolites downstream of chanoclavine-I aldehyde in Arthrodermataceae have not been identified yet (PubMed:22403186).
What are the official names of this protein?
Tryptophan dimethylallyltransferase, 4-dimethylallyltryptophan synthase, DMATS, All-trans-hexaprenyl-diphosphate synthase, L-tryptophan dimethylallyl transferase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: IF2G_HALSA
Sequence: MADEHRQPEVNIGLVGHVDHGKTTLVRALSGEWTDQHSEEMKRGISIRLGYADATLRRCPDCDEPECYTVAETCPEHDTATEIERTVSFVDAPGHETLMATMLSGAALMDGAVLVVGANEPVPQPQTEEHLMALDIIGIENIVIAQNKVDLVDAEEARQNYEEIQAFVEGTVAEDAPVVPVSAEQEINVDLVIDALQTEIATPDRDPSADPLLYAARSFDINRPGTEWGGLLGGVIGGSLVDGELEAGDELELRPGREVEEGGKTEWRPVTTDVRSLQAGGEDVDSASPGGLLGVGTGLDPSLTKGDALAGQVAGPPGSLPPTWESFEMDVDLLERLVGAADGEQIDDISTGEPLMLTVGTATTVGSVTSARDGECEVALKRPVCAPAGAKIAINRRVGARWRLIGVGTLTESE
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit gamma, aIF2-gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: CRCB_SHESM
Sequence: MNNLLLVALGGSIGAVFRYLISIFMIQVFGSSFPFGTLLVNVLGSFLMGVIYALGQMSHISPELKALIGVGLLGALTTFSTFSNETLLLMQEGDWLKAALNVVLNLSLCLFMVYLGQQLVFSRI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.