PharMolix/UniProtQA huggingface dataset:
Protein: PAK5_HUMAN
Sequence: MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCITPIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHAEENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEAYYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTAGTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFGASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQSQSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSSDQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH
What is the function of this protein?
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival.  Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues.  Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity.  Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD.  Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology.  Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.
What are the official names of this protein?
Serine/threonine-protein kinase PAK 5, p21-activated kinase 5, PAK-5, p21-activated kinase 7, PAK-7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the mitochondria, and mitochondrial localization is essential for the role in cell survival.
Protein: RS7_SHESR
Sequence: MPRRRVVGQRKILPDPKFHSELLAKFINVIMQDGKKSTAEKIIYKALDVIAEKKGANHLDILEAALDNVRPSVEVKSRRVGGSTYQVPCEVRPVRRNALAMRWLVEAARKRGEKSMALRLAGEMLDASENKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: P9_RDVA
Sequence: MGKLQDGIAIKRINDAITTFKNYKLGELEQGGSMAINTLSNVRAHVGLAWPAILRNCLIHTSSHLGFMKFMIDIATTWKVGAFTLLGSVGDEDPFTDVDLIYTKTCLHLGLKDNDFLQFPEEFAYEANSFLEAQSMNARVDMLTGVHNIEDKYVFRMQSISKFLKAYYTASEDVAYLTGFIKPDDSKDSILSAELLKAQVTSEVLRVRNLITTKIQKYINLYEDSQLPHFRQAALSYTQDWDVDGGVPAALPQPDTTDDENPVANPGPSAPTVSKGADQPEDEEMIRKKVETSKDGPPKAVPSGNVSARGFPAFLEDDMSEMDAPDGFHDYLTREHENNFDLTQLGLAPSV
What is the function of this protein?
Minor outer capsid protein.
What are the official names of this protein?
Minor outer capsid protein P9.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus minor outer capsid protein P9 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Found in the peripheral regions of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: LIPB1_MOUSE
Sequence: MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAEVLIEWLQNQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELMAEISNLKLKLTAVEKDRLDYEDRFRDTEGLIQEINDLRLKVNEMDGERLQYEKKLKSTKDELASLKEQLEEKECEVKRLQERLVCKAKGEGIEVLDRDIEVQKMKKAVESLMAANEEKERKIEDLRQCLSRYRKMQDPAVLAQGQDSECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDLLHTSAPEEFHTSVLQASIPSLLPPSVDVDTCEKPKLPTKPETSFEEGDGRAILGAAAEVSLSDGVSTSSLQKSSSLGNLKKEASDGTDKAPTDSRTFGTLPPKVPGHEASVDDNPFGTRKARSSFGRGFFKIKSGKRTASAPNLAETEKETAEHLNLAGTSRSKGSQGTSPFPMSPPSPDSRKKSRGIMRLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIISGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENSITPSEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMELGQASGSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
What is the function of this protein?
May regulate the disassembly of focal adhesions.  Did not bind receptor-like tyrosine phosphatases type 2A (By similarity).
What are the official names of this protein?
Liprin-beta-1, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1, PTPRF-interacting protein-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the liprin family. Liprin-beta subfamily.
Protein: INS_GORGO
Sequence: MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SECA_LACLM
Sequence: MPNIIRKLVENDKKELKKLNKMALQVESFADEMEHLTDEQLKAKTPELKERIAKGESLDDLLYEAFAVCREAARRVLGLYPFHVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLATRDMTEMGELYSWLGLTVGLNLNSKSPEEKREAYNCDITYSTSAELGFDYLRDNMVTRAEDMVQKPLNYALVDEVDSILVDEARTPLIISGQAESSSALYYRADQFTKTLKGQNLNVATSDYEEGDDYKIDLQSKTISLTEEGIDKAEKFFQIENLYDMENVALTHFVDNALRANFIMLHDIDYMVDENQEVLIIDQFTGRTMPGRRYSDGLHQAIEAKEAVPIQDESKTMASITIQNYFRMYKKLSGMTGTAKTEEEEFREIYNIQITPIPTNRPVQRLDHPDLLYPTLEAKFKAVIDDIKRRHAEGQPILIGTVAVETSELISKKLVEAKIPHEVLNAKNHFREAQIIMNAGQQGAVTIATNMAGRGTDIKLGPGVIDHADPEFRGLAVIGTERHESRRIDNQLRGRSGRQGDPGVSQFYLSLEDELMKRFGSERVSAFLDRMRISGEDAVIKSGLITRQIESSQKRVEGNNYDSRKQVLQYDDVIREQREVIYAQRQEVILTKEDMTPVLMGMFKRTIDRQVDGHELAGNLKDEETVKDLLQTVQNTMLPEEAIELSELTGLSGQAMKDLIFDKVKSRYASQMEKLADPERQLEFQRAVILRVVDNNWSEHIDALDQMRQSVGLRGYAQNNPIVEYQEESYKMYNNMIGAIEFEVTRLMMKAQIQPQTAIRQEAPRMTTTASQENITNVGPDTSVSEEISFENVGRNDPCPCGSGKKFKNCHGRTHIA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: PANB_CORDI
Sequence: MTRPVRLQDLRDYKKNNRPWAMLTTYDYSTTRAFVDAGIEVFLVGDSAANTMLGYSGTNQVSFEEMVMLTAAVVRGAGPAMVVADLPFGTYEASDEQAVRSATEMVRRTGAHVVKLEGGVRMASRIRAITDAGVPVCAHLGFTPQSMNQLSGFKVQRGAEKLTADVDAVVEAGAEMVVFEMVPADLAAELTARCPIPVIGIGAGNATDAQVLVWHDIANLPKGDHRARFVKTYAEVGSQLTCAARFYRKDVEARRFPAEEHTF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCE2_MYCTT
Sequence: MVHLTSALLVAGAAFAAAAPMNHIFERQDTCSVSDNYPTVNSAKLPDPFTTASGEKVTTKDQFECRRAEINKILQQYELGEYPGPPDSVEASLSGNSITVRVTVGSKSISFSASIRKPSGAGPFPAIIGIGGASIPIPSNVATITFNNDEFGAQMGSGSRGQGKFYDLFGRDHSAGSLTAWAWGVDRLIDGLEQVGAQASGIDTKRLGVTGCSRNGKGAFITGALVDRIALTIPQESGAGGAACWRISDQQKAAGANIQTAAQIITENPWFSRNFDPHVNSITSVPQDHHLLAALIVPRGLAVFENNIDWLGPVSTTGCMAAGRLIYKAYGVPNNMGFSLVGGHNHCQFPSSQNQDLNSYINYFLLGQGSPSGVEHSDVNVNVAEWAPWGAGAPTLA
What is the function of this protein?
Glucuronoyl esterase which may play a significant role in biomass degradation, as it is considered to disconnect hemicellulose from lignin through the hydrolysis of the ester bond between 4-O-methyl-D-glucuronic acid residues of glucuronoxylans and aromatic alcohols of lignin.
What are the official names of this protein?
4-O-methyl-glucuronoyl methylesterase, Glucuronoyl esterase 2, GE2.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 15 (CE15) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_SULAC
Sequence: MNPIRSVKEEFCEIVANGLGISKDVIFKTLEYPPREELGDISLPLPSLKLNVRTEVTFSHGKLIKEVRKTGIYVNAFVDEKELFKLLFTEMQDDYGVEKTENPKRIVVEHTSANPIHPLHIGHLRNSILGDTISRMLKIRGHDVNRRFYVNDAGRQVAILTLGYILLGEPEPSPKVDHWFGLIYSITNVIIEIRELKEELKKDLDPDTYKDKINRLDELVATAQSLRERNPEFFDKLADAINSIPDVESEIQKIIKSYEKGDDPKIKQIVRKIVNLNLDGFRESLDKLEISFDVYDYESELLWSGMVDEILSKAFQIAKDYKGTKALELEDINEKIKEILNIPKGLKLPPLVLTRSDGTSLYTTRDIAYTVKKFSDFKADTVINVIAEQQSIPQMQLRASLYLLGYERLAQNLVHYSYGMVNLQGMRMSGRLGRFISLDDVIEKVSEVAKKKIEEKSGDITNLRDIVNSAIRYAILSVASNKPVTFNINNIVDFEQNSGPYLQYTYARAYNILAKNQDEIKLTDADLSDLIGDKRRLLLLIARFPETFNKAIDELRPEDLIDFLRRTADVFNRWYNFERVLQEPDYRKRITRLFIVKGIERVLYNGLNALGIKPLSKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNE_RHOPS
Sequence: MNSSAIDADIPPSALAARFAAGPQLHAPEEAEKRLADWLGDVPADLAGAIRSVADRHPHVGVALRSIAEASPYLFDLIRADPARLLGLLRSDPEAGFVALLDRASAAVAAASDEAEVMAVLRKMKAEAALSIALCDIGGLWPVMQVTQALTDLAVNSVQMTLRFLLRQEAARGRIIPPNSDAPEQGSGLVVLAMGKMGAGELNYSSDIDLIVFYDLDAPTLAPDIEPQPFFVRVTQGLSRILQQRRHDGYVFRVDLRLRPDPASTPVALSTVSALNYYEREGRTWERAAMIKARACAGDLVAGEALLGDIAPFVWRKHLDFAALSDVHDMKRQMQTFRGQTEVAVEGHNVKVGRGGIREIEFFAQTQQLIAGGRHPELRVRPTLAALDILAARDWITYQARDELSVAYQFLRRVEHRIQMIADEQTHTLPDSVEAVERFSRFFGYESREAFARDLLAYFDCVQGHYGKLFEGDPTGTVKLPIDYAGGPDDTGLLDHLHGLGYKKPLMVATTLQQWMTGGYRILKVETTQRAFHEFVPMLIEELARAEEPDNAVNAFDRLLQALHRGGRLISLLSQNRDLLTLVALVLGAAPRLGDMLARQPQILDGLIDPRFFGAMPDRAELSARLAATLADAGPYEEFLDRLRLFGQESLFLIGTRILSGTVSTQQASVAFADVAEGIVGTVHDLVSEQFISQYGRIKDQQTAILAMGKLGSREMTASSDLDLILIYDFDHEQPDSDGERSLQGAQYFARFTQRLISAFTTRTNYGVLYDVDMRLRPSGRAGPLASRLDSFAEYQEVEAWTWEHLALTRARVISASPEFRERIEQVIRAVLTRPRDAAIIANDVAEMRHAIAQEKGEDDVWDMKYAAGGMVDIDFIAQYLQLVHAAATPEILGVSTLGAIDNAARLGVLAQSDAEVLRPAARLYHDLTQILRLCVSDKFKPETAGEDLLRVLVRAGDAPDFSSLEARVKETQAEVRAIFNRLIGGDSA
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: NU6M_AETPY
Sequence: MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVAGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPEAWGDWGVVGYGVGFVVVLVVGLVVGGFVGSLDFGVVTVDSVGMFSVRLDFSGVAMFYSCGVGMFLVAGWGLLLTLFVVLELVRGLSRGAIRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RL19_NITEU
Sequence: MNLIEQLEREEIERLGKTIPDFSPGDTLVVNVNVVEGDRKRVQAFEGVVIAKRNRGLNSSFIVRKISSGEAVERTFQTYSPLIASMEVKRRGAVRRAKLYYLRDRSGKAARIREKLPARSVQQENVAEALQP
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ISPH_THEP3
Sequence: MKILIAEYAGFCFGVKRAIETAYQEIEKGDGKKIYTLGEIIHNPQVISDLSKKGVNVIEEEELDKLTEGDKLIIRSHGVSKKLYDFLAKKGVEVIDVTCPFVKKVQNIVYEYYHKGYSIIIVGDRNHPEVIGVNGWCDDTAYVVNSIEEAYELPQLEKACAVAQTTLIEKHWKDILEVIKLKVKDLIFFNTICDATQKRQDAADELSKKVDVMFVIGGKHSSNTQKLKKICEKNCKNTFHIEDAEELTLEMVKDHEIIGVTAGASTPDYVIEDVIKKIRFLKGEDGDE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: SYL_BURPS
Sequence: MHERYVPADVEAAAQSDWRAADAYRSKEDANRKKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAQWTYENIAYMKKQMQSMGLAIDWSREVTTCKPDYYKWNQWLFLKMLEKGVAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPMYYMRITQYADELLNDLDGLGWPERVKVMQHNWIGKSFGVNFGFPYELDGEKKLLRVFTTRADTIMGVTFCAIAAEHPLAARLARDKPALQAFIDECKRGGVAEADIATMEKKGVATGFSVSHPLTGEPVEVWIGNYVLMSYGEGAVMGVPAHDERDFAFAKKYGLPIRQVIAVEGETYSTDAWQEWYGDKTRAVCVNSGKYDGLAHDAAVDAIAAELKAGGLGDKQITYRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDLVPDGTGNPLAKSDAFLNCTCPKCGAAAKRETDTMDTFVDSAWYFSRYAAPDAQTMVDARTDYWMPMDQYIGGIEHAILHLLYSRFWAKVMRDLGLVAFGEPAKNLLTQGMVLNETFYREDAAGKKTWYNPADVTVSFDDKGRPVGAVLKSDGQPVELGGIEKMSKSKNNGVDPQMLIDHYGADTARLFTMFAAPPEQQLEWSGAGVDGASRFLRRVWAFGFANREALAVRAPFDAAQLAEADKTLRREIHGVLKQADFDYQRLQYNTVVSAAMKMLNAIEGAKGATPAVLRETYGVLLRVLYPVVPHVTFELWKALGYADEFGPLLDAPWPKVDEAALEQAEIELVLQVNGKVRGALKVAKDASREAIEAAAVADGMFAKFAEGRPAKKIIVVPGRLVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCM5_ORYSI
Sequence: MSGWDEGAVFYSDQAQFPRGGPGGDPSADLTRHSALRKFKEFLRGFTGPTGDFPYRESLVHNRDHVTVAIEDLDAFDAELSDKIRKSPADYLPLFETAASEVLASLRSKVAGETGEMEEPASGDVQIFLSSKENCLSMRSIGADYMSKLVKIAGITIAASRVKAKATHVTLLCKNCRSVKTVPCRPGLGGAIVPRSCDHVPQPGEEPCPLDPWIAVPDKSKYVDLQTLKLQENPEDVPTGELPRNMLLSVDRHLVQTIVPGTRLTVIGIYSVYQASANQKGAVGVKQPYIRVVGLEQSRDANSNGPSNFTLDEEMEFKEFAQRPDAYVKICSMIGPSIYGHSDVKKAIACLLFGGSKKRLPDGVRLRGDIHVLLLGDPSTAKSQFLKFVEKTAPIAVYTSGKGSSAAGLTASVIRDGSSREFYLEGGAMVLADGGVVCIDEFDKMRPEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIAGRYDDLKTAQDNIDLQTTILSRFDLIFIVKDVRMYDQDKRIASHIIKVHASGAAASSKNTDASEGENWLKRYIEYCRVTCKPRLSEKAAEMLQNKYVEIRQKMRQQAHETGRAAAIPITVRQLEAIIRLSESLAKMRLTSVATPEHVEEAFRLFNVSTVDAARSGINEHLNLSPDIANEIKQAEAQIKRRMGIGSHISERRLIDELNRMGMNESIVRRALLIMHQRDEVEYKRERHVIVRKA
What is the function of this protein?
Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.
What are the official names of this protein?
DNA replication licensing factor MCM5, Minichromosome maintenance protein 5.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACP_NITOC
Sequence: MSDIETRVKEIVVEQLGVNSEEVANESSFVDDLGADSLDTVELVMALEEAFECEIPDEEAEKISTVQEAINYIKERQG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIOC_SCHPO
Sequence: MGSQQSKLDFRNAVLRLHEERNIPKFDLIWERLWTLPETTEDVFHLMSIDDLTKVKDNAPENLQTIIAVLWDKLEDLQKETLFDDPAAPTTKCALNCMRLLTRLMPIIFEDKSMLEWFDYFAWTVPKDPNINTPRGASFLNTVVDYLFLINFTIPAHNDLTHGVHYCIWETGVVYHPTMLKERSYELHRVEVLRLLLSLFSEEIYRTDGNGSSCCAYVASIANRRLVLCLLSSLINTAMRFNTMFWKPEFLPLDNSVAHMSLIEYCFSVLLILMSEENNNGTPCYNNYRSSKNTLPKNYFSILLSKLQPYSDFQIILDGMSRLLYPPMQSTIPKRSSLIMFDYYPLVLIFCKLFIHYNERFFHYLIDTDRAIDLFIFLLYLSFEYLGDPSTYNHLKLCVILLKRLTAEKYFCKRLNKPFQQQTALPISMPVPFEGGTYADFTIIAISLLVQYTKDYHSEIAQMLCCSLCYLCLYAQNLNSHSSQSLFELFQSASYPGFLISNDVNHKILKYVIGAINNAIQYAQKYNAPLLYFFSMHKDYIEAVSALSFDAIMSVRNSSAEGDSAYWTRNGKTFSSKAFDSILLSRLRYVRSKSPTPYYPIESSEFGFTNLKDVTSKDEITDGFDKALRSNSLRTHRDSRPVQPLLKQRPQLHRALTESATLHGNDRSLEDTDEAKVEPIAHSVDYTFKPTVEWWNKWWPSLNFRTMLDIFTDLSLKISDMKKAGHPASEIMAMIKTQKYPATNQPYIPKYRTKEWRQQLANFARLFAWQVSCDLDSHKREGPGIFEGTDVKIFDSF
What are the official names of this protein?
Hid-1 family protein P27G11.12, Down-regulated in multiple cancers 1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the hid-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPIA_HERAR
Sequence: MTQDEMKQAVARAAIEYVVPGEIIGVGTGSTANFFIDELGKIKDRIKGAVASSEATAQRLKSHGIAVFDLNEIDAMSVYIDGADEITAQGAMIKGGGAALTREKIVASVAKQFVCIADGSKLVDLLGNFPLPVEVIPMAQAVVARKLAALGGEPRLRLKDGKPLVTDNGCFIIDVLGLKIQDPAELEAQINNIVGVVTVGLFARRGADIALLGTAEGVKRLTF
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: MIAA_DEIRA
Sequence: MAAPLIPVLTAPTAAGKTALALRLAREYGLEIVAADAFTVYRGLDLGTAKPTPQERASVPHHLLDVVDVTQSYDVAQYAAQAEAAIVDILARGRLPLVVGGTGFYLSALSRGLPLTPPSDPKMRAALEAELQERGLDALLAEIEQANPAEAARMERNPRRVVRALEVYRAAGRFPGEFGYSPPAFQYQVFAFSPPAAEMEQRVQERTAAMLRAGWPQEAQWLAGQVPPEQEPRPTVWQALGYAEALAVAQGRLSLAGAEQAIALATRQYGKRQLTWMRRQLGAEVQSPDAAEAHLRAFLERSGAPS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: Y425_YERP3
Sequence: MNKQPEDWLDDVPENKNDDDDEIIWVSKSEIKRDAEALKDLGTELVDLGKNALERIPLDEDLLAAIELAQKIKKEGRRRQIQLIGKMLRARDVEPIQTALDKLKNRHNQQVSLFHKLETLRDRLIAEGDDAIPTVLELYPDADRQQLRSLVRNAQKEQAANKPPKSFRQIFSYLRELAEKQQ
What are the official names of this protein?
UPF0307 protein YpsIP31758_0425.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: SYT_CENSY
Sequence: MRILQLHCDRIEYSPVKKEIAAAEEPATGGKLEDAVLAFVAVEKGDGPGEAARAAAELRQALGRIGCKKLLIYPYAHLSSTLAAPSIALGLISEMEAALHDLEVSRAPFGWTKSYTISVKGHPLAEGFKVITGDARGTGAPKALESESSMKSTWHVLTPDGNMTDASEFDFAGCPKLKALARYEASKKRGTDEPPPHVALMKRMGIADYEPASDAGNMKFFPNGRLIKSLIERYVTERVVEYGGYEVETPIMYDSNHPSMVSYFNRFPARQYSIDSEGKSLFLRFAACFGQFLMAGDYQLSYKNLPFRLYELTRYSFRREQSGELVGLRRLRAFTMPDCHAFCTDMAQAVREAGVRFELSRDVIGQLGLDAADYEMAIRLTEEFYAENGGAVREMVRRHGRPVLVEMWKERFFYFVLKWEFNYIDGAGKASALSTDQIDVENGKRYGIEFVDENNGRQHPVILHNSPSGAIERVIYTLLEKAAADSARGTKPELPLWLSPVQARIIPVGEELVRNATELAKEMAGHGIRADVDDRNESMGKRIREAEKEWVRYILVVGEKEAASGRLSVRDRRTGKSTEMGLDDLVEAVREQTAGKPSAGLNSPFYLSKRPQVML
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_ECOL5
Sequence: MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALSDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_BACC3
Sequence: MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNEAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_STRGG
Sequence: MANAPFPKLSASLDQGRPHRVRFCPSPTGNPHVGLVRTALFNWAFARHHQGTLVFRIEDTDAARDSEESYQQLLDSMRWLGLDWDEGPEIGGPHAPYRQSQRMDLYKDVAEKLLAAGYAYPCYCTTEELDTRRDAARAAGKPSGYDGHCRDLTAEQKAAYEAEGRTSIVRFRMPDEAITFTDLVRGEITVQPENVPDYGIVRANGAPLYTLVNPVDDALMEITHVLRGEDLLSSTPRQIALYRALIELGIAKDTPAFGHLPYVMGEGNKKLSKRDPQASLNLYRERGFLPEGLLNYLSLLGWSIAEDRDIFSMDELVAAFDIKDVNANPARFDLKKCEHINAEHIRMLDVKTFTEACGPWLKAPFAPWAPEAFDAEKWTRIAPYAQTRVTVLSDITDNVDFLFLDEPVEDEASWTKAMKGDPVALLTTARANLEAADWSDPESLKNAVLTAGEAHGLKLGKAQAPVRVAVTGRTVGLPLFESLEILGRDRSLARVDAALAKLTA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDN11_RANSP
Sequence: GLLDGLLGTLGL
What is the function of this protein?
Caeridins show neither neuropeptide activity nor antibiotic activity.
What are the official names of this protein?
Caeridin-1.1/1.2/1.3.
What are the subcellular locations of this protein?
Secreted.