PharMolix/UniProtQA huggingface dataset:
Protein: ARP5_HUMAN
Sequence: MAANVFPFRDARAAPDPVLEAGPVAHGPLPVPLVLDNGSFQVRAGWACPGQDPGPEPRLQFRAVCARGRGGARGASGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYGIPKVAYGIDSLFSFYHNKPKNSMCSGLIISSGYQCTHVLPILEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILHEHSYIAEDYVEELHKWRCPDYYENNVHKMQLPFSSKLLGSTLTSEEKQERRQQQLRRLQELNARRREEKLQLDQERLDRLLYVQELLEDGQMDQFHKALIELNMDSPEELQSYIQKLSIAVEQAKQKILQAEVNLEVDVVDSKPETPDLEQLEPSLEDVESMNDFDPLFSEETPGVEKPVTTVQPVFNLAAYHQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLQYILDRYPKDIQEMLVQNVFLTGGNTMYPGMKARMEKELLEMRPFRSSFQVQLASNPVLDAWYGARDWALNHLDDNEVWITRKEYEEKGGEYLKEHCASNIYVPIRLPKQASRSSDAQASSKGSAAGGGGAGEQA
What is the function of this protein?
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.  Involved in DNA double-strand break repair and UV-damage excision repair.
What are the official names of this protein?
Actin-related protein 5, hARP5, Sarcoma antigen NY-SAR-16.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP5 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear but undergoes nucleo-cytoplasmic shuttling (PubMed:19014934). Localized to interphase nuclei, but not nucleoli; excluded from chromosomes as mitosis progresses (PubMed:18163988).
Protein: HFQ_HYDCU
Sequence: MENKKVAKALPIQDPYLNALRKEKINVAIYLVNGVKLQGRVDSFDQFVVLLRSNVTQMVYKHAISTIVPARDPKAYEFEAQETEAKDSE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: UDB33_MACMU
Sequence: MSVKWTSIILLIQLSFYFSSGSCGKVLVWAAEYSHWMNMKTILEELVQRGHEVTVLASSASILFDPNNSSALKIEVFPTSLTKTEFENIIRQQIKRWSELPKDTFWLYFSQIQEIMWRFGDISIKFCKDVVSNKKLMKKLQESRFDVVLADPIFPCSELLAELFNIPLVYSLRFTPGYVFEKHCGGFLFPPSYVPVVMSELSDQMTFMERVKNMIYVLYFDFCFQLYDMKKWDQFYSEVLGRHTTLSEIMGKADIWLIRNSWNFQFPHPLLPNVDFIGGLLCKPAKPLPKEMEEFVQSSGENGVVVFTLGSMITNMKEERANVIASALAQIPQKVLWRFDGNKPDTLGVNTRLYKWIPQNDLLGHPKTKAFITHGGANGIYEAIYHGVPMVGIPLFADQPDNIAHMKTRGAAVQLDFDTMSSTDLANALKTVINDPLYKENVMKLSRIQRDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWFQYHSLDVIGFLLACVATVIFIIMKCCLFCFWKFTRKGKKGKSD
What is the function of this protein?
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.  This isozyme has glucuronidating capacity on estriol and does not catalyze the glucuronidation of beta-estradiol.  Capable of conjugating 4-hydroxyestrone, androsterone, diclofenac, and hyodeoxycholic acid.
What are the official names of this protein?
UDP-glucuronosyltransferase 2B33, UDPGT 2B33.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RS4_THEPD
Sequence: MGDPKKPRKKWQGPSHPWRKETLLEEMQLVGEYGLRNKRELWIAKSLLREIRAKARKLLALPAEERIKLEKPLVSRLYKMGLLPSEDASLDDVLSLTVRDVLERRLQTIVYRKGLATTIRHARQLITHGHIAVNSRRVRSPGYLVSRDEENFISYYEGSPLAKMAQGGAQNV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: LIS1_DROPS
Sequence: MKMVLSQRQREELNQAIADYLGSNGYGDSLETFRKEADVSTESEKKFGGLLEKKWTSVIRLQKKVMELEAKLTEAEKEVIEGAPTKNKRTPGEWIPRPPEKYSLTGHRASITRVIFHPIFGLMVSASEDATIKIWDFETGEYERSLKGHTDSVQDVAFDSQGKLLASCSADLSIKLWDFQQSYECVKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDHTIRVWLMNSKDCKVELRDHEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLCLLTLNGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes.
What are the official names of this protein?
Lissencephaly-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the plus end of microtubules and to the centrosome.
Protein: HIS3_FRAAA
Sequence: MTVRPSALDPAIASRLRRNDAGLFPAIAQQHDTGEVLMLGWMDDEALHRTLTTGRATYWSRSRGEYWVKGDTSGHQQWVRSVALDCDGDAVLVRVDQIGPACHTGTRNCFVADPLPTRVGDPGVTADAGPAR
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPA_ARCFU
Sequence: MHEMSFAEAIIRNVLRFAEEKQAKTVTSVRVRVGELLLINPEQLQFCFSVASKGTIAEGAKLEISVERADIRCLLCGRELSKDEMLCECGGFAQVKGGKDFILESVVVEV
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: SYEM_XENTR
Sequence: MRPAFIRGKWLSRTLELATGLGRRTCSSRESGREVRVRFAPSPTGFLHLGGLRTALYNYLFAKKHGGAFILRLEDTDRSRLVPGAAESIEDMLEWAGIPPDESPRHGGPCGPYEQSKRLDLYHVAAQALLDSGAAYRCFCTPQRLELLKREAMRNRQTPRYDNRCRHLTPKQVEEKLSRNSPFVIRFFLQEGAQPFQDLVYGWTQHDVASVEGDPVILKGDGFPTYHLANVVDDHHMCVSHVLRGAEWLISTAKHLLLYQALGWQPPQFAHLPLLLNKDGSKLSKRQGDIFIQHYVHSGYLSDALLDLITNCGSGFTENQMGRTVDTLIQQYELGKTSTHSALLDLDKLPEFNRIHLTRWIEGTETRVQLVGQLQVLLKDTYKDLELDEKHIERILLLRKGHLCRLTDLLSPEYSYLWVRPSVTREQLQCLTSEASKVKNLVVRLLQENDSGFTLETLNGELRKQLKQVKDTKYSSAMKLLRVALSGQEHGPSVAEMLLSLGRQESIVRLQNALPD
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Probable glutamate--tRNA ligase, mitochondrial, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DAPB_HALMA
Sequence: MTRVAVNGVTGQMGGAVIEAATDSEVVVGFATSDTDAVDDVPVVHPAEAAAALREYDVDVVVDFAVPKGALTVAEACVEAGVPMVVGTTGFDEDGLARLQDASEEIPLLKATNFSQGIQVLQRLISEAVGTLDDYDLELMETHHNRKVDAPSGTASSILDVIQEERDVEPVYGREGHAPREDDEIGVFARRAGDVRGEHELVLAGNDEVLSLSHRAEDRGVFAAGALDAATWLVGRDSGWYEFGDVVDA
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_ARABL
Sequence: MEKFQGYLEFDGARQQSFLYPLFFREYIYVLAYDHGLNRLNKNRSIFLENADYDKKYSSLIVKRIILRMYEQNRLIIPTTDLHKNLGHTNLFYYQMISVLFAVIVEIPFSLRLGSSFEGKQLKKSYNLQSIHSIFPFLEDKLSHFNYVLDVLIPYPIHLEVLVQTLRYRVKDASSLHFFRFCLYEYCNWKNFDIQKKCILNPRFLLFLYNSHICEYESIFFFLRKRSSHLRSTAYEVFFERILFYGKIQNFLKVFVNNFPAMLGLFKDPFLHYVRYHGKSILATKDTPLLMNKWKFYFVNLWQCYFSVWFQSQKVNINQLSKDNLEFLGYLSSLRLNPLVVRSQMLENSFLIDNIRIKLDSKIPISSIIGSLAKDKFCNVLGHPISKATWTDSSDSDILNRFVRICRNISHYYSGSSKKKNLYRINYILRLCCVKTLARKHKSTVRAFLKRLGSGLLEEFLTGEDQVLSLIFPRSYYASKRLYRVRIWYLDILYLNDLVNNE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: QUEA_SHESM
Sequence: MRVTDFSFDLPDELIARYPMAQRNASRLLTLDGNTGTLADKQFTDLLGMINPGDLMVFNNTRVIPARLFGQKASGGKLEILVERMLDDKRILAHVRSSKSPKVDSIIHLDGGYEMKMAARHDALFELELLSDLTILEVLEAVGHMPLPPYIDRPDEDADKERYQTVYNQNPGAVAAPTAGLHFDDAMLDALKAKGVNIAFVTLHVGAGTFQPVRVDNVLEHKMHSEWANVPQDVVDLIAQTKAAGKRVVAVGTTSVRSLESAARASEGELKAFSGDTDIFIYPGYQFQIVDAMITNFHLPESTLIMLVSAFAGFDHVMAAYQHAITQKYRFFSYGDAMFVTKKAH
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_MYXXD
Sequence: MMKVLIAGGGTGGHLFPGIALAEEVVTRHHRNEVVFVGTERGIESRVVPKEGYPLELVKVQGLKGKGFLSLLKALFALPLAFIESFRILARQKPDVVVGVGGYASGPVVMAAWLMGIPTAIQEQNALPGFTNKVLGRIVRVVFIAFEEARAFFPEKKVQLIGNPIRRKLMDNYLRSHVAHERFSVLVFGGSLGARGINQRMTEALDSLGDLKDSLHFVHQTGKNDLESVRKGYADKGFQAEVVEFIDDMSSAYARADLVVCRAGATTLAELTVCKKASILIPFPHATDDHQAVNARALVDAGAALMFRESELTGEKLAQTVRELKSHPERLKSMEKKAGLLGRPEAAKELADVCVDLMVQTWGPNGRERTPIEAEKKAPRSNS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EDNRA_CANLF
Sequence: METFCLKVTFWVALVGYVIGDHPESYSTNLSTPVDFTTFHGTELSFLVTTHRPTNLALPSNGSMHSYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLRLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHEQNNHNTERSSHKDSIN
What is the function of this protein?
Receptor for endothelin-1.  Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity).
What are the official names of this protein?
Endothelin-1 receptor, Endothelin receptor type A, ET-A, ET-AR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNLI4_CRIGR
Sequence: MATSQTSQTVAAHVPFADLCSTLERIQKSKERAEKIRHFKEFLDSWRKFHDALHKNKKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPREGKDALKLLNYRTPSGARTDAGDFAVIAYFVLKPRCLQKGSLTIQQVNELLDLVASNNSGKRKDLVKKSLLQLITQSSALEQKWLIRMIIKDLKLGVSQQTILNIFHNDAVELHNVTTDLEKVCRQLHDPAVGLSDISITLFSAFKPMLAAVADVERVEKDMKQQSFYIETKLDGERMQMHKDGSVYQYFSRNGYNYTDQFGASPQEGTLTPFIHDAFRTDVQVCILDGEMMAYNPTTQTFMQKGVKFDIKRMVEDSDLQTCYCVFDVLMVNNKKLGRETLRKRYDILNSTFTPIQGRIEIVQKKLAQTKNEVVDALNEAIDKREEGIMIKHPLSIYKPDKRGEGWLKIKPEYVSGLMDELDLLIVGGYWGKGSRGGMMSHFLCAVAEKPPHGEKPSVFHTLCRVGSGYTMKELYDLGLKLAKYWKPFHKKSPPSSILCGTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGTTLRFPRIEKIRDDKEWHECMTLGDLEELRGKASGKLATKHLHVGDDDEPREKRRKPVSKMKKTIGIIEHLKAPNLSNISKVSNVFEDVEFCVMSGLDGYPKSDLENRIAEFGGYIVQNPGPDTYCVIAGCENIRVKNIISSDQHDVVKPEWLLECFKTKTCVPWQPRFMIHMCPSTKQHFAREYDCYGDSYFVDTDLDQLKEVFLGIKKAGEHQTPEEMAPVIADLEYRYSWDHSPLCMFRHCTVYLDLYAVINDSSSKIKATRLDVTALELRFHGAKVVSHLSEGVSHVIIGENQSRVSDFKVFRRTLKKKFKILQERWVTDSVDKGELQEENQYLL
What is the function of this protein?
DNA ligase involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair and V(D)J recombination.  Catalyzes the NHEJ ligation step of the broken DNA during DSB repair by resealing the DNA breaks after the gap filling is completed.  Joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction.  LIG4 is mechanistically flexible: it can ligate nicks as well as compatible DNA overhangs alone, while in the presence of XRCC4, it can ligate ends with 2-nucleotides (nt) microhomology and 1-nt gaps.  Forms a subcomplex with XRCC4; the LIG4-XRCC4 subcomplex is responsible for the NHEJ ligation step and XRCC4 enhances the joining activity of LIG4.  Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.  LIG4 regulates nuclear localization of XRCC4.
What are the official names of this protein?
DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMH_LACDB
Sequence: MNIKIVCVGKLKEKYFKDGIAEYQKRLSRFAKVEIVQVPDEKAPESLSPAQMEEVKKREGERILSKIKDKEYVYVLAIKGKERASEEFAKELKNLGTYGHSDITFVIGGSLGTSDAVNKRANDLFSFGKLTMPHQLMRLVLIEQIYRAFMINSGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_SYNSC
Sequence: MPKISKRLASLAGKIEDRAYAPLEAIALVKDNANAKFDETMEAHVRLGIDPKYTDQQLRTTVALPNGTGQSVRIAVVTRGEKVAEAKAAGAELAGEEDLVESISKGEMDFDLLIATPDMMPKVAKLGRVLGPRGLMPNPKAGTVTTDLEAAIKEFKAGKLEFRADRTGIVHVRFGKASFSADALLQNLKTLQETIDRNKPSGAKGRYWKSLYVTSTMGPSVEVDFSALQDIEQGS
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RAC2_ARATH
Sequence: MSTARFIKCVTVGDGAVGKTCMLISYTSNTFPTDYVPTVFDNFSANVVVDGSTVNLGLWDTAGQEDYNRLRPLSYRGADVFLLAFSLISKASYENIHKKWLPELKHYAPGIPIVLVGTKLDLRDDKQFLKDHPGAASITTAQGEELRKMIGAVRYLECSSKTQQNVKAVFDTAIRVALRPPKAKKKIKPLKTKRSRICFFL
What is the function of this protein?
Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation.
What are the official names of this protein?
Rac-like GTP-binding protein ARAC2, GTPase protein ROP7.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Associated with the membrane when activated.
Protein: RL2_FRATH
Sequence: MIEIKKAKPTSPGRRHVVSVKNTELHTGKPFKGLVEVKKSKAGRNNTGRITVRHQGGGHKQHYRIVDFKRNKDDITAKVERIEYDPNRSANIALVLYADGERRYIVAPKGLKKDMSVISGEKVDIAVGNCMPLRNIPLGTVIHNIEMKPKKGAQMIRSAGTFAQLVGKDNAYAIIRLRSGEMRRVLLDCRAVIGVVSNSEHNLKSLGKAGAKRWRGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGIPTKGYKTRRNKRSNKLIVQKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS10_PSEF5
Sequence: MQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLVSPHVNKDARDQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MURC_ENDTX
Sequence: MFLKNQNIHFVGIGGSGMSGIAEVLINLGHRVSGSDLKKTDVTEYLKAVGAKIYIGHSCKNIKSAEVVVTSTAISRNNPEVVAALKKRIPIIARIEMLVELARLKYAVTITGTHGKTTTTSLTSLVLHNGGLDPTIVIGGRLKNLKTNAKLGRGDYIVVEADESDGSFLRLSPIITVVTNIDNDHLDYYDSMENLKEAFVKHINCIPFYGTAIICSDNEVVRKIIPQITRRYITYGLMGNPDIKASNIKVLKNHTSFDVFYMRKKVGSVCMKILGKHNVSNSLAAIGVGLRLGISFSSIADTINKFDGVSRRLEIKGEKNGMMVIDDYGHHPTEVAATLRAIKLFWPERRLVVLFQPHRYTRTKQLFNEFGRSFSDADFVKVLDIYSAGEQPIDEVTSDLILESLVSNKCKAEKFSDLEEFSKGLSVGDVVLTLGAGDVWKKGEELLALI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDPH2_EMENI
Sequence: MASLTTLKNTAIVTGSFLSGAMITLSTITVPVLLETSTHPPQLLHQWVRTYHYGHISLPTISIATAILYFYIAAYQGAREQPWRKAALVGFLTIVMVPFTWIVMSSTNGMLFGLEAGNRDHSQFFEQGANRSGLKGANSSQSHGLGNVSVGIGVEMATLEGVRELLVRWKWMHLVRSLFPLMAAVLGVGICV
What is the function of this protein?
Anthrone oxygenase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative (PubMed:20139316, PubMed:21351751, PubMed:22730213).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG (PubMed:20139316).  The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG (PubMed:20139316).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone by mdpH-1 and mdpH-2 (PubMed:20139316).  Emodin is further modified to yield monodictyphenone via several steps involving mdpB, mdpC mdpJ, mdpK and mdpL (PubMed:20139316, PubMed:21351751).  These enzymes with xptA, xptB and xptC are also proposed to be involved in the synthesis of shamixanthone from emodin (PubMed:22730213).  Especially, direct reduction of emodin by the short chain dehydrogenase mdpC followed by dehydration catalyzed by the scytalone dehydratase-like protein mdpB gives loss of oxygen and formation of chrysophanol intermediate in two simple steps (PubMed:22730213).
What are the official names of this protein?
Anthrone oxygenase, Monodictyphenone synthesis protein H-2.
What is the protein family that this protein belongs to?
Belongs to the anthrone oxygenase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ENO_BACCR
Sequence: MSTIIDVYAREVLDSRGNPTVEVEVYTESGAFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVVNAVNNVNEIIAPEIAGFDVTDQAGIDRAMIELDGTPNKGKLGANAILGVSMAVAHAAADFVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNVDFQEFMILPVGAPTFKESIRMGAEVFHALKAVLHDKGLNTAVGDEGGFAPNLGSNREALEVIIEAIEKAGYKAGENVFLGMDVASSEFYNKETGKYDLAGEGRTGLTSAEMVDFYEELCKDFPIISIEDGLDENDWDGHKLLTERIGDKVQLVGDDLFVTNTQKLAEGIEKGISNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDRIAKYNQLLRIEDELGEVAVYDGVKSFYNIKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PUR1_MYCBO
Sequence: MAVDSDYVTDRAAGSRQTVTGQQPEQDLNSPREECGVFGVWAPGEDVAKLTYYGLYALQHRGQEAAGIAVADGSQVLVFKDLGLVSQVFDEQTLAAMQGHVAIGHCRYSTTGDTTWENAQPVFRNTAAGTGVALGHNGNLVNAAALAARARDAGLIATRCPAPATTDSDILGALLAHGAADSTLEQAALDLLPTVRGAFCLTFMDENTLYACRDPYGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLAIDADGVRSTRFANPTPKGCVFEYVYLARPDSTIAGRSVHAARVEIGRRLARECPVEADLVIGVPESGTPAAVGYAQESGVPYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRGNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVENEDEMLEAVRHAIGADTLGYISLRGMVAASEQPTSRLCTACFDGKYPIELPRETALGKNVIEHMLANAARGAALGELAADDEVPVGR
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPATase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: IF1_FRATF
Sequence: MAKEDCIEMEGVVLEALPNTMFRVELENGRIVTAHISGKMRKNYIRILTGDKVVVEITPYDLTKGRIKFRSK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIP2_ORYSJ
Sequence: MYHPQCELLMPLESLEMDVGQSHLAAAVAAAMPGELNFHLLHSLDAAAAAASSTAASASSQPTVDYFFGGADQQPPPPAAMQYDQLAAPHHHQTVAMLRDYYGGHYPPAAAAAAATEAYFRGGPRTAGSSSLVFGPADDESAFMVGPFESSPTPRSGGGRKRSRATAGFHGGGPANGVEKKEKQRRLRLTEKYNALMLLIPNRTKEDRATVISDAIEYIQELGRTVEELTLLVEKKRRRREMQGDVVDAATSSVVAGMDQAAESSEGEVMAAAAMGAVAPPPRQAPIRSTYIQRRSKETFVDVRIVEDDVNIKLTKRRRDGCLAAASRALDDLRLDLVHLSGGKIGDCHIYMFNTKIHSGSPVFASAVASRLIEVVDEY
What is the function of this protein?
Transcription factor that binds to the E-box-containing promoter regions of the transcription factors TDR and EAT1, activating their expression.  May have a role in specifying the cell pattern of the inner anther walls and functioning in meiosis progression.  Required for male reproduction (PubMed:24755456).  Acts downstream of UDT1 and GAMYB, but upstream of TDR1 and EAT1 in pollen development (PubMed:24894043).
What are the official names of this protein?
Transcription factor TIP2, Basic helix-loop-helix protein 142, OsbHLH142, Basic helix-loop-helix protein TIP2, TDR INTERACTING PROTEIN2.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.