PharMolix/UniProtQA huggingface dataset:
Protein: METK_METS3
Sequence: MRNIIVKELNQTYIEDIDIEIVERKGIGHPDSISDGIGETVSEALCKMYMDELGGVLHHNTDEVQITAGESNPVFGGGKILKPIDILLTGRGVSEYDGIKFPLDRVAIEAAKNFLDDTIINLDVELDTVVECKIGHGSGDLVDVFKREGAPSSNDTSFGVGYAPFSETETLVKATEELLNSKPFKAKHPAVGEDIKVMGLREGEKITLTIGCAMVSKFVANREEYIAVREELKDIVSDLATKYTNREVEVFVNTADNDDATDESGYYLTVTGTSAEMGDDGSVGRGNRANGLITPCRPMSMEASSGKNPINHVGKIYNILSNEIAKDVVENVEGIKQMNVMILSQIGKPIDQPKAASTQVILEDGVKLEDVDKKVEQIVDRWLEDISIITENVVQGKTRTF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: TVC2_MOUSE
Sequence: MLLLRWPTFCCLWVFGLGQLEQTELSVTRETDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVWI
What are the official names of this protein?
T-cell receptor gamma chain V region V108B.
Protein: A1751_ARTBC
Sequence: MLVQGTIICALVANAIASSIPSSFLLPEPSGPFKVQREILELTDWSRKDINSTLPRRLMVSRFNPIPEKHCIRTEDVPTFPPASAKLEDAILQAASGGHWVDGLLAASRIRVCADVKKGYQTDSHGDNHGIPILLFSPGGNTTRLVYSSIAQTISSAGYTVITMDHPHDTDIVEFLNGDIITGGEVTFSNPSVLPFWNDVRVQDTVFVLNQALKTSPHARIGMLGHSFGGSAVLSSMVKDGRISAGINFDGGLWGDAVNTGLGGRKKPQPYLQWGAYTHNRHNDTSWETLWKAMERLHPHAWKKELGIPAGRHNTFSDFPAIIDAGGVREVIGKASIDVLVGDIPAARSLEFIKVYVHDFFQFSLFGKDEGLLRGPSSKYPEVVFLD
What are the official names of this protein?
Probable 1-alkyl-2-acetylglycerophosphocholine esterase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTU_KOSOT
Sequence: MAKEKFERTKPHLNIGTIGHIDHGKTTLTAAITKALAYKGFADFTPFDAIDKAPEEKARGITINVTHVEYETEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAATDGVMPQTREHVLLARQVNVPAMVVFINKVDMVDDEELVELVEEEVRDLLSKYEFPGDEVPVIKGSALMALEADNPDDPWVQKIYELMDAVDNYVPEPQRETDKPFLMPIEDIFSITGRGTVVTGRIERGVIHVGDEVEIVGLSYEVRKTVVTGVEMFRKLLDEGVAGDNVGCLLRGVGKDEVKRGQVLAKPGSITPHKKFKANIYVLKKEEGGRHTPFTKGYRPQFYIRTADVTGELVDLPEGVEMVMPGDNVVMTVELIYPVAIEKGMRFAVREGGRTVGAGVVSEIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_THEP1
Sequence: MGWWLFPILGYFIGSIPFSYLIPKWLKGIDVRKVGSGNVGATNAIRTTGPVVGGICLLLDALKGFFPVFIATTFSGDPKLVSLTAIATVLGHDFPIFMKFKGGKGVASTLGIIFCLSWPTGIVFTLTWLVIVMLTKYASLGSLVALYISALLGYLFKGYDTGMLILILAVLSTLRHSENIQRLLNGTERKVNLFKR
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TBSYN_GARMA
Sequence: MAPAMDSAQNGHQSRGSANVLAIGTANPPNVILQEDYPDFYFKVTNSEHLTDLKEKFKRICVKSKTRKRHFYLTEQILKENPGIATYGAGSLDSRQKILETEIPKLGKEAAMVAIQEWGQPVSKITHVVFATTSGFMMPGADYSITRLLGLNPNVRRVMIYNQGCFAGGTALRVAKDLAENNKGARVLVVCAENTAMTFHGPNENHLDVLVGQAMFSDGAAALIIGANPNLPEERPVYEMVAAHQTIVPESDGAIVAHFYEMGMSYFLKENVIPLFGNNIEACMEAAFKEYGISDWNSLFYSVHPGGRAIVDGIAEKLGLDEENLKATRHVLSEYGNMGSACVIFILDELRKKSKEEKKLTTGDGKEWGCLIGLGPGLTVETVVLRSVPIA
What is the function of this protein?
Type III polyketide synthase involved in the biosynthesis of benzophenones and xanthones.  Produces mainly 2,4,6-trihydroxybenzophenone together with minor amounts of tetraketide lactone, triketide lactone and diketide lactone.  The preferred substrate is benzoyl-CoA, but can also use acetyl-CoA, phenylacetyl-CoA, hexanoyl-CoA, cinnamoyl-CoA, p-coumaroyl-CoA and salicoyl-CoA.
What are the official names of this protein?
2,4,6-trihydroxybenzophenone synthase, GmBPS.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: GACHH_DICDI
Sequence: MSWSSIKLSRLPDATISVWGHTATISGEKDIVIFGGFDFCIEKPTNTTYILHTSQTNGLTKPSVSGSLPPPIYGHSSTQVGRKMFVFGGSLQDNVQVNDMYQFNTSNYSWSKPRPMGEPPIPRYGHSASLIYDNYILIFGGNNTKSSKPLNDIHIFNTERNSWTKPSSNSSTGEIIFNPHDISPRSSTTTPTHQSVNGSNSNSSSSSRVRSATISSHNNSPIVMPLNNNNNNNNNSNNSNNSNNNGGGSPMTTPPTLQQLHLSQLMANGIGMGGSISNGNSDSPPLTPSMMALESSMLNGFKSPLSLSQRLLRSGFRSSPPSARYFHSCSVINGKAFIFGGYNGTTLLNDLYILNIESMEWICPHTKGDLPTPRAGHTSIAIGSRLFIFGGTIEGDPSSSNAHCDNDLYMFEPELNYWTLLKTSGTLPSPRTGHVCLPISSKILIIGGSDAILNNKLKLSNTYHSLETLKLDFSHYSRGGSGGGSNNNIIIHPITSSNSTSSNSIITNYLPHLKPRSSSNSGGGGGSITNTPTTSSLHIKDNSASPSPLTPRSIARNSPKSSIFHDNINNNSNNNLLNTLQEASKFELSPGTPKSIRGIDSLSSVSLTQSIDRNGGSGGGSGGGNGVVSNDRGEFLRHYTTQSILINKNNNNNNNNNSGGSNLSISSNSGSNNSINSNDGLVLQCSTPLCIKKYNSLKDSYLELKQKYQEEREKRLELEKELERYRLSSPITSASSLVDTLSSPNNLNINSNNSTTTTTTTTTTTTTPIPLSTSNNNNNNNNNSTLTVQDQVTTSKQILEIYEDIYNLWGYYEKRVKWKENTEKEANQQLEVIKSKIDLFTSMVGLENHFSFNDDTKSCCSENINGDHNQQQQQQQQQNPQFQIDDNISETNSQISEPALIHETLTPRKSRENSVHHSRSVSNPIPLLSQIVKQSKSGDSTLTVPQQLHSSHNNLIQLASISTPQKPPQQPQQQQQQQPPQENGKEPSKSTQKIFKLLISKKNRASGHFKLSSSNESSNSEETTPTFSNNPNLINDEDDDSQQHQQQTNIGSNSISNINTSNSTTSLSSSVSSTSLQTQEEFEASERSKQKKRLGKALKQMINKDRQLKETAAAALAVSNSNGNLGGGGGGGSINGTTNVSGNGANNLGGLVLTSDKEKEKLEKEREKSERIEREKQEKEREKLEKEREKSERIEREKLEKAEKERLEKEKIEKEKLEKKHKKIKGLFGAKSSNKESLPFRRDVIEKVINHLRENSLDTEGIFRLSGNMESVRGIVKSFAHGEPNLSFEVHNISNALKHYLRSLDPPLIPYEFFLMLLDARKNEDAETIRNIFWKIPSDNRVVLTLLVDLMVKISENSNVNKMNSKNLSIVFGPTILKPRTPTLDRMALMTETQLQCGIIQTFIEDFHYIFSEFPTSGPKSFLGDDDYDSSSFGSNNTPSSHSPHSSSPTLNPAVTTTTTTTTTTNTTTTTNTTTTPTSATISPNIIQTNNCDSALCTPTTLSSTAAIIQSNNNNRTDSNRNN
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacHH, GTPase activating factor for raC protein HH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_COPPD
Sequence: MRVDDLRQYIRDIPNFPTEGVIFRDITPLLKNPDAFATTVDLMAEAVSSLNVTAVAAVEARGFIWGGTLAYRLGVGFIPIRKPGKLPFEVVEKEFELEYGKDVLQIHKDAAGPGDSILIVDDVLATGGTAQAAADLVNTLGADVAGFCFLLRLGTMDGYERLSKLGKKVFYLLTV
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGP1_SOLTU
Sequence: MAAATPLLKDELDIVIPTIRNLDFLEMWRPFFQPYHLIIVQDGDPSKIIKVPEGFDYELYNRNDINRILGPKASCISFKDSACRCFGYMVSKKKYIYTIDDDCFVAKDPSGKDINALEQHIKNLLCPSTPHFFNTLYDPYRDGADFVRGYPFSMREGAPTAVSHGLWLNIPDYDAPTQLVKPHERNTRYVDAVMTIPKGTLFPMCGMNLAFDRDLIGPAMYFGLMGDGQPIGRYDDMWAGWCTKVICDHLGLGIKTGLPYIWHSKASNPFVNLKKEYNGIFWQEEIIPFFQAATLPKECTTVQQCYLELSKQVKKKLSSIDPYFTKLGEAMVTWIEAWDELNLLGTTWLSCLSPMVQQRLKSRCY
What is the function of this protein?
Probable UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides (By similarity).  Was initially shown to possess an autoglycosylating activity which is dependent on the presence of UDP-glucose and manganese (Probable) (PubMed:10580281).
What are the official names of this protein?
Probable UDP-arabinopyranose mutase 1, Reversibly glycosylated polypeptide 1, RGP1, UDP-L-arabinose mutase 1, UDP-glucose:protein transglucosylase 1, UPTG 1.
What is the protein family that this protein belongs to?
Belongs to the RGP family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell junction, plasmodesma. Golgi apparatus. Note=Cell wall-associated, with highest concentrations on plasmodesmata. Also located in the Golgi apparatus (By similarity).
Protein: GRPE_ZYMMO
Sequence: MTEEQKKYEDAENLESKSENPEEASAEKSENGVEDLQAENEKLKKDLLYSKAEAQNTRRRLEKEKSEAIAYSVTGFARDMLSVADNMERALAAIPDDIKQDEKIKNLVTGIEMTGKELLNILQRHGIKRVESVGQKLDPNLHQAMIEIESEKPEGTVVQEMQAGYTIHDRLLRPAMVGVAKAQSGETKSA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1067_YERPP
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDPGANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDEDNNMETIIYEGYGPGGTAVMVECLSDNRNRTVSEVRHAFTKTGGNLGTDGSVSYLFTKKGVISYAPGLEEDTVMDAALEAGADDIVVYDDGAIDVFTAWESLGAVKDALDATGLVAEGAEVSLIPSTKAELDAETAPKLLRLIDMLEDSDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein YPDSF_1067.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOX1_PLEWA
Sequence: MVWSRGQRRKMAQENPKMHNSEISKALGADWKLLSDAQKRPFIDEAKRLRAVHMKD
What is the function of this protein?
Transcriptional activator.
What are the official names of this protein?
Transcription factor SOX-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ESXG_MYCS2
Sequence: MSLLDAHIPQLIASEANFGAKAALMRSTIAQAEQAAMSSQAFHMGEASAAFQAAHARFVEVSAKVNALLDIAQLNIGDAASSYVAQDAAAASTYTGI
What are the official names of this protein?
ESAT-6-like protein EsxG.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-3 / type VII secretion system (T7SS).
Protein: DS_PERHD
Sequence: MSTAVNVPSAVRPADKRPIASFHPSPWGDYFLKYVPCDQVTQAKMEDEVKKVEEDVKKELRKLAKAVGKPLELLNFIDVVERLGVGYRLEQEIEDLVQAIFDNDKFGVDEFDLYHTSLWFRLLRQHGFHVSCDVFGKFKGRNGRFKDSLASDVKGILGLYEASHVRTHGDDTLDEALVFTTTHLKAVVTNQPNHPLVPQVTHALMQPYHKGMPRLESRHFIAFYEKDPYHDKTLLKFGKLDFNLVQALHKKELKDLSRWWKDLDMHAKMPFPSRDRVPEGYFWTLGPFYEPQFALCRKFFLQVFKVTSIVDDIYDAYGTIDELTAFTKAAERWDRSCLDELPEYMKVSYASLIDTFEEFERDLAPQGRSWSVKYAREEMIQMCRVYYQEAKWCHEKYSPTCDEYLEKASIVSFGYNLGTVVCFLGMGDVATKEAFEWARGNPKVVRAAGIIGRLMDDIGSHHFEQGRDHVPSAVECYIRQHGVDEVTAQRELGKRVESSWKDINEMMLKPYMMPKPLLTRILNECRIVDVIYKGEDSYTFSNTTMKKNISHILTDPIPI
What is the function of this protein?
Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into drimenol, a precursor of the sesquiterpenoid polygodial (PubMed:28258968).  Polygodial has been shown to be an antifeedant for a number of herbivorous insects (Probable).
What are the official names of this protein?
(-)-drimenol synthase, PhDS, Drimenol cyclase, Sesquiterpene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: MURB_LEGPA
Sequence: MDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLPFDEPLLWLGLGSNSLIRDGGFSGTVILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSARNNLSEGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQTINRRGEIRTRKPEEFEVAYRHVAGLGDEWFISAKLQLTPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAARLIESCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIREVHIIGDANVQTR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL2_HPV09
Sequence: MVRAKRTKRASVTDIYRGCKAAGTCPPDVINKVEHTTIADKILQYGSAGVFFGGLGISTGRGTGGATGYVPLGEGPGVRVGGTPTIVRPGVIPEIIGPTDLIPLDTVRPIDPTAPSIVTGTDSTVDLLPGEIESIAEIHPVPVDNAVVDTPVVTEGRRGSSAILEVADPSPPMRTRVARTQYHNPAFQIISESTPMSGESSLADHIIVFEGSGGQLVGGPRESYTASSENIELQEFPSRYSFEIDEGTPPRTSTPVQRAVQSLSSLRRALYNRRLTEQVAVTDPLFLSRPSRLVQFQFDNPAFEDEVTQIFERDLSTVEEPPDRQFLDVQRLSRPLYTETPQGYVRVSRLGRRATIRTRSGAQVGAQVHFYRDLSTINTEEPIEMQLLGEHSGDSTIVQGPVESSIVDVNIDEPDGLEVGRQETPSVEDVDFNSEDLLLDEGVEDFSGSQLVVGTRRSTNTLTVPRFETPRDTSFYIQDIQGYTVSYPESRQTTDIIFPHPDTPTVVIHINDTSGDYYLHPSLQRKKRKRKYL
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: NSL1_YEAST
Sequence: MSQGQSKKLDVTVEQLRSIYHQFHDILEEKTDLHLPKKEYDDDAVRREVQIQLQEFLLSAMTMASKSLEVVNADTVGKTVKQLIMESQEKYMEPFDLDLNEQVRKMYQEWEDETVKVAQLRQTGPAKINEVYNNSKDEYLAQLDGRIGVLQARMMQQQSADHDDSTDDADDHINWEHIKQDYVASLNELYQTQQDLPKVRYNVEKVKRLMDFLEED
What is the function of this protein?
Acts as essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity.  MIND plays a role in establishing a bipolar spindle-kinetochore interaction by joining kinetochore subunits contacting DNA to those contacting microtubules.  NSL1 facilitates the attachment of two of the DASH complex components, DAD2 and SPC19, to the kinetochore in a microtubule-dependent manner.
What are the official names of this protein?
Kinetochore-associated protein NSL1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore (PubMed:12455957, PubMed:14657030).
Protein: RSMG_ORITI
Sequence: MLQQIYDFLNINYNVSRETFNKFKEYYSLLSKWNSTINLVSATTLQNFWQRHIFDSIQLLNYIHNKDIIVADLGSGAGFPGVVLSISGIKNVILIESDSRKAAFLLQVAQLSDQKIEIINDRIQNLKVKCDIVTVRALANLSTILSHTKQFTVKDKYLILKGKNYQHEITQALLHNKFNYRLYKSCTDDSSWILEIKI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1392_LEPBP
Sequence: MAQDPSFDIVSKLERPELQNAVSQAMTEIQTRFDFKGSNSEIKITDDQLVLTSENEIKLKQVIDVLTTKMAKRGIGLKAFDFDSKVESATGQTVRMKVKIQNGLDKEQTKQITTLIKDQKLKVQATIQGDSVRVVGKKKDDLQEVMAAIRNANFNFDANFTNFKG
What are the official names of this protein?
UPF0234 protein LEPBI_I1392.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: TOTX_DROSE
Sequence: MRLYIGSLLICVLLGIVPFATANTNRSGYEEHRNYLLNIFHNPLVNDSIKEKNIPELIAFYQRYPTDIPLSDADRQQFERFIHDYREYREVLVDGVPPQGGSFGNIFGHFLGRVGTRYISSLFNKKREEGQSNHANSPTTSPSRIQKMTK
What is the function of this protein?
A humoral factor that may play a role in stress tolerance.
What are the official names of this protein?
Protein Turandot X1/X2.
What is the protein family that this protein belongs to?
Belongs to the Turandot family.
What are the subcellular locations of this protein?
Secreted.
Protein: SUCC_FRATO
Sequence: MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVIKAQVHAGGRGKAGGVKVVKSSQEAREVAESLIGKNLVTFQTDAEGQPVNSVGIFEDVYPVTRELYLGAVVDRSSRKVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQAREVAFKLGLEGKQINDFVKTMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQENAKELKASEHELNYVALEGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVIEAFKLILDDENVKAVLINIFGGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAKILADSGLKLIPADGLADAADKVVKSLG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: HEMH_BURP0
Sequence: MSFDSVPRHALSMRFDLEPPSHASAAHRVAVLLVNLGTPDAPTPRAVRRYLAQFLSDPRVVEIPQLVWQVILRTLILPLRGRASAKKYAAVWLPEGSPLRVYTERQVESVKPLFAANGYRVIVDYAMRYGTPSIADVLAQLKRAGAERVLLLPMYPQYSSSTTATAFDAAFAALGRMRNQPEVRTVRHYADHPAYIHALAEQVRQYWAAHGRPAFDAGDKLVLSFHGVPKRTLDLGDPYHDQCQQTAALLMSALGLTTFECRVTFQSRFGKAEWLQPYTAPTLKELGAAGVRRADVFCPGFTADCLETIEEIGIEVRDEFVHGGGKEFHRIPCLNASPAWIAALGEIAAENLQGWPVRVAMAPEAVS
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP2_EHDV1
Sequence: MEDINLTIFSDDALPHAVVVDDYVIAIKRNPNGTFLEPHQMYDRYTQEFLQGKARDVLRQNGRDGYKLIIPEALSTGIIRYENKTKGAQSEVELENQLRSSIRHQRVKPRMDEAHRKLQIELRGGQILLHPRIAESIEFSIISKENATCSHTPVNCAYEVLLSGGINVGTGTCYDLSSRLKLRVIGDVDRHRRSMQNVLGRVIHTGDPKIINRVNQIGSQQFIDRAIGPDKFELKREIFDRLKALDVDVRKVIREEEASAELDEMGRRWMRDQNVNIVNDIIQSLVKKGSRSEKLAHRNEQGMQARFRRTIATNLRDQRQGKEVLNIRGTRGQPEEKKFAAVLLMTGCDIVERAIWSNEETAILRGLYAYAHDKLGCVYRAMKKDFVWSIRPTYTDRCAGVCDRKRTIMVREDYFDLQREENDSVYKWIITEWDKNDVIISAKNGYLYSKYSGEDEDDILVHEIDDRLYTAMIDRILINGWIEKEGLSQIIKEEVRLESFDFTKDAYVDEAGFLVLPEYYDRVIASNIYDCKFKISRVSITSSSNDDPWDKKTADSIIDEQCLWKIPLPNIIDVRPCFRGDLLTSNSQEYSKRFSGIIDELKKDKEIYDDFIPVQEGVRPCVQGHVCRYAFYRQKLTIFTILKRYYPIERILELTDEEDYEYNLYLDKECYKKESLILNLRSIFSLICFLIDFGYEGREITRGEDEYLKIFNEINYGGHARKEAINKYFPQFYQRLMRVRTSENIEDLLPLAFYQALLLSDPCTDNSEKSSHPLILFCQDKVRVVPIRTATQERGLPLLCCIHIFKFHPGLQMRKKELEDDIKKTLPAIFDYWIELEMKRLDTGDRLRTRAQMVELYYSTNCGGSYETLNFVFPIVHPNKGFIACVISSKGGMGALNEDDVRRRFRRIQSSIQGIFSISIDEEMEIQLHHSGNIQARILEKVFFEHKWHIVQVKLNGKIFENHELITKLMN
What is the function of this protein?
The VP2 protein is one of the two proteins (with VP5) which constitute the virus particle outer capsid.  It is the major target of the host immunogenic response.
What are the official names of this protein?
Outer capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP2 family.
What are the subcellular locations of this protein?
Virion.
Protein: PKHO1_BOVIN
Sequence: MMKKNNSTKRGPQDGNHQCAPPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISEKEVKDEKNIQEVFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSKQPGNTAPNLIFLAVSPEEKESWINALNSAITRAKNRVLDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPTSCAESFRVDLDKSVAQLAGSRRRADSDRIQPSSDRASGLPRLWEKPDKGATYTPQAPKKLTATEKSRCASLEEILSQRDAVPAHTLQRRAEDPPTPIPHAPGQLSRIQDLVARKLEKTQELLAEVQGLGDGKRKAKEPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDLYRQMDLQTPDSHLRQTTQHSQYRKSLM
What is the function of this protein?
Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP).  May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2).  Appears to target ATM to the plasma membrane.  Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF.  When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation (By similarity).
What are the official names of this protein?
Pleckstrin homology domain-containing family O member 1, PH domain-containing family O member 1.
What are the subcellular locations of this protein?
Membrane. Nucleus. Cytoplasm.
Protein: MUG_ECOL6
Sequence: MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQAGFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELDQALVVRGR
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1341_AZOVD
Sequence: MPSFDVVSELDKHEVTNAVDNAIKELDRRYDLRGKGSFEFKDKTLTLTAEADFMLEQMIEILKLALIKRKVDIQCLEYKDSYASGKVVKQEVILREGIDKDLAKKIVALIKDSKLKVQAAIQGEQVRITGKKRDDLQEAIALLRGQELGMPLQFNNFRD
What are the official names of this protein?
UPF0234 protein Avin_13410.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RS13_NEIM0
Sequence: MARIAGVNIPNNAHIVIGLQAIYGIGATRAKLICEAANIAPDTKAKDLDETQLDALRDQVAKYEVEGDLRREVTMSIKRLMDMGCYRGFRHRRGLPCRGQRTRTNARTRKGPRKAIAGKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.