PharMolix/UniProtQA huggingface dataset:
Protein: PROA_RHIME
Sequence: MLETVEKDKDVNAMMLEIGRRAKAAARPLATASAERKHAALVAMAGVIVTRTAEILAANALDLENARESGVASAFIDRLTLTESRIRDMADGIRAIAELIDPVGEVISEWDRPNGLHIERVRTPLGVIGVIYESRPNVTADAGALCLKAGNAVILRGGSDSFHSSRAIHACLTEGLKVAGLPEDAIQMVPVADRAAVGAMLTGLNGAIDVIVPRGGKSLVARVQNEARVPVFAHLEGLCHIYVDASADRDMAKKIVVNAKMRRTGICGAAETLLIDRNAAEKFAKPLLEALVDAGCEVRASDDLASVMPGLKAATDEDWATEYLDAIISARLVDGISGAIEHINTWSSAHTEAVIAEDPAVVERFFSEIDSAILLHNASTQFADGGEFGMGGEIGIATGKMHARGPVGVEQLTSFKYRVRGTGQVRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CF144_HUMAN
Sequence: MAGHPKEKVIPDEVHQNQILRELYLKELRTQKLYTQYHVNPLRKIHTVTRKPMSWHDNLEEPADARFLNLIHHAAQGPRKKYPETQTENQEVGWDLEPLINPERHDRRLNHFRVCSDITLYKAKTWGLGDDHHK
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
Cilia- and flagella-associated protein 144, Protein FAM183A.
What is the protein family that this protein belongs to?
Belongs to the CFAP144 family.
Protein: MDTH_BLOPB
Sequence: MYTISKARRLGKCFLIIDNMFVVIGFYVVFPLISIYFVEQLGWGAFLVGFALGLRQFIQQGLGIFSGAFADKLGAKPMIVSGLFIRTLGFIIMSVANTPLLLCLSCMLSALGGTLFDPPRTALVIKLVRPWELGRFYSVLMLEDSMCAIIGIVLGTWLLQYNFKLVCFTGAILFFIAGVFNAWRLPAYKISSSHASLLEGIKKVLNNQRFVIYVFTLTGYYILSAQVMLMLPIRIHEVSGQLSYIKWMYIIEAILSLLLIMPITWWSEKYFKLETRLMVGLITMIISLFPIGLVKNLHTLLILISLFYIGSIIAEPARETLGALLTDYKARSSYIGFSKLSLALGGTVGYSGSGWLYDIGKEQNFTQLPWIILSIIGLITLLGLYCQFKYYSFQSLLNNSHNKKRKL
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KTI2_ARATH
Sequence: MKNPSVISFLIILLFAATICTHGNEPVKDTAGNPLNTREQYFIQPVKTESKNGGGLVPAAITVLPFCPLGITQTLLPYQPGLPVSFVLALGVGSTVMTSSAVNIEFKSNIWPFCKEFSKFWEVDDSSSAPKEPSILIGGKMGDRNSSFKIEKAGEGARANVYKLTTFYGTVGAIPGVWLSAPQLIITKDTAKTLLVKFKKVDDATTATSNLYFPG
What is the function of this protein?
Water-soluble and chlorophyll-binding protein that probably does not function as a chloroplast chlorophyll carrier and is not involved in photosynthesis (PubMed:11577184, PubMed:26160583).  Involved in the control of cell death in the transmitting tract and septum epidermis during flower development.  Binds and inhibits the activity of the cysteine protease RD21A as a pro-death protein (PubMed:26160583).  May play a role in herbivore resistance activation during seedling greening (PubMed:26016527).
What are the official names of this protein?
Kunitz trypsin inhibitor 2, AtKTI2, Cysteine protease inhibitor WSCP, Kunitz-type cysteine protease inhibitor WSCP, Water-soluble chlorophyll protein, AtWSCP.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast. Endoplasmic reticulum. Note=Targeted to ER bodies.
Protein: ATPE_HYDCU
Sequence: MAVSMQVDIVSAEGSLFSGKADMVFAQAADGEVGILPKHTQLLTQLKPGQVRVVSGDEEDSFFINSGVLEVQPSVVTILADTAIRAEDLDQAAAEEAKRRAEDAMEQAKSDTDIARAQIELAEAVAQIQTITKLRDRLHKTGLS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RECU_STRE4
Sequence: MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAYYLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAKETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQIDRGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_SHELP
Sequence: MHCPFCSATDTKVIDSRLVADGHQVRRRRECLLCHERFTTFEGAELVMPRVVKQDGSRQPFDEDKLRGGMLRAVEKRPVSMDEIEQALSKIKSTLRATGEREVTSKMIGNLMMDHLVNLDKVAYIRFASVYRAFEDVSEFGEAIAKLQNDKSKSGKS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SYT_COLP3
Sequence: MPVITLPDGSQRSFEQAVSVMDVALDIGPGLAKATIAGRIDGNLVDACELITQDASLQLITSKDSEGLEIIRHSCAHLLGHAIKQLYPNVKMAIGPTIENGFYYDIDLDESISEDDLVKLEKRMTELARTGYEVVKKTGSWQDAYDAFTERGETYKLAILDENIEKTDTPALYHHQEYIDMCRGPHVPSMRHCHHFKLMKVAGAYWRGDSDNKMLQRIYGTAWADKKQLKAYIVRLAEAEKRDHRKIGKTLDLFHWQEEAPGMVFWHNDGWTIYTELEKFIREKLHEYDYDEVKAPMMMDRSLWEKSGHWDKYADGMFTTTSEKREYAIKPMNCPGHVQIFNQGLKSYRDLPLRIAEFGCCHRNEPSGSLHGLMRVRGFTQDDAHIFCMESQVQAEVKKCIEMVYDVYGSFGFEDVVVKLSTRPDNRIGSDEIWDKAEAGLAQALTDSNIAFEYLPGEGAFYGPKIEFTLMDCLGRAWQCGTVQLDFALPERLGATYVGEDNERYTPVMIHRAILGSLERFIGILIEEFTGKFPTWLSPIQTTIMNITDKQAPYCEKVVKKLKENGFRAKIDLRNEKIGFKIREHTLKRVPYLLVVGDKEMESGEISVRTRSGEDLGKMSVDDFIAKLSDEVKSRQ
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT5C_CONVC
Sequence: VILLLLIASIPSDAVQLKTKDDMPLASFHGNARRTLQMLSNKRICCYPNEWCCD
What are the official names of this protein?
Conotoxin vc5c, Vc5.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VE1_HPV24
Sequence: MADNKGSETDGLHEWCLLEADCSDIENDLDTLLEQNSDSDVSDLISNDGDLEQGNSRELFQQQELEESNALLQSLKRKYISPKAVLQLSPQLESISLSSDHKTKRKLFAEQDSGVELTLTNETEDVTTLVQQEEEVPALETSSTSNLRKEDNAHYKELMRCSNLKATLLSKFKNAFGVSFVELTRQFRSNKTCCNDWVVAIYGVNYDLFESSKQLLQQHCDYIWVTEMSAMFLYLLCFKAGKNRQTVIRLLVSMLYVAEEQILSEPPKLRSTVSALFWYKGSSNAATFTHGSYPKWIIEQTLIGHQTGEAATFDMSTMVQWAFDNDLTEEADIAFQYAKLAPDDVNATAWLAHNNQARFVRECANMVRYYKKGQMREMSMSAWIHFKLEQVEGEGQWSTIVKFIRYQGINFISFLSALKDFLHGKPKKNCLLIYGPPNTGKSAFTMSLIKVLHGRVISFVNSKSHFWLQPMSEAKIALLDDATDPCWIYMDTYLRNGLDGHLVSLDCKHKAPIQIRFPPLLITSNINAMAEPNYRYLHSRLVAFEFPNPFPMKDDDTPEFELTDQSWKSFFKRLWRQLDLSDQEDEGEDGEPEKAFRCVARSTNEHL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: DLTA_STRZP
Sequence: MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDSLAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEVAEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTTGKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGTLFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDGEELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADSPTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGTMTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLLAYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKGLINEVNKR
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALC_CHICK
Sequence: MVMLKISSFLAVYALVVCQMDSFQAAPVRPGLESITDRVTLSDYEARRLLNALVKDFIQMTAEELEQASEGNSLDRPISKRCASLSTCVLGKLSQELHKLQTYPRTDVGAGTPGKKRNVLNDLDHERYANYGETLGNN
What is the function of this protein?
Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
What are the official names of this protein?
Calcitonin.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FGF21_MOUSE
Sequence: MEWMRSRVGTLGLWVRLLLAVFLLGVYQAYPIPDSSPLLQFGGQVRQRYLYTDDDQDTEAHLEIREDGTVVGAAHRSPESLLELKALKPGVIQILGVKASRFLCQQPDGALYGSPHFDPEACSFRELLLEDGYNVYQSEAHGLPLRLPQKDSPNQDATSWGPVRFLPMPGLLHEPQDQAGFLPPEPPDVGSSDPLSMVEPLQGRSPSYAS
What is the function of this protein?
Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression).  Activity probably requires the presence of KLB.  Regulates systemic glucose homeostasis and insulin sensitivity.
What are the official names of this protein?
Fibroblast growth factor 21, FGF-21.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: XKR6_MOUSE
Sequence: MAAKSDGGGVGVGFAQLHNLDEAVGSGEEDGEPGGGGCGGGDGSEPGESSSLHICHCCNTSSCYWGCRSACLRSLLGKKPRRSAAAADGGDQPLQPPGAAGRHPPTPSAGRPQPASPQVERPWLDCLWIVLALLVFFGDVGTDLWLALDYYRKGDYGCFGLTLFFVLVPSLLVQSLSFRWFVQDYTGGGLGAVEGLSSRGPPMMGAGYGHGAARGGPGAGGSATPGAQRLCRLSVWIWQSVIHLLQMGQVWRYIRTMYLGIQSQRQKEHQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLCIMIQKNSAETLPCVSSVTSLMSLAWVLASYHKLLRDSRDDKKSMSYRGALIHLFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFCWFNVKEGRTRYRMFAYYTIVLTENAALTFLWYFYRNPESTDSYAVPALCCVFVSFVAGITLMLLYYGVLHPMGPRAKVFASSCCAELLWGIPLPPDVEPMAPQTPGYRGTQVTPTRAVTEQQEDLTADTCLPVFQVRPMGPSTPSGRPYHPEGPLIKIDMPRKRYPAWDAHFVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL
What are the official names of this protein?
XK-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PABC_VIBCH
Sequence: MYWVNGQRRNEVPIHDRSFQYGDGCFTTILTKEGQVQQWSSHKARLQACLDILHIPEPNWDRVWQGLQSMILPQEKAGLKIHISRGLGGRGYSPTQVSESIVTISAFAFPAHYQAWRDKGLAVGICQQRMGLNPLLAGHKHNNRLEQILLKREMDNAGWDDGVCLDINGKVIETTAANIFWCRDGTMFTPCLRHAGVAGVARRQILELAQQQEIPIVIDEFTLEDLLSAEEVFITNALLEVAPVTQIGQQRLTIGSMTRRFQESSNS
What is the function of this protein?
Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate.  Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate (By similarity).
What are the official names of this protein?
Aminodeoxychorismate lyase, 4-amino-4-deoxychorismate lyase, ADC lyase, ADCL.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: ARND_ECO24
Sequence: MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQARSSNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQKVIEAKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVVRGNIAGREGWLGCQQIAGSR
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: A1KA6_LOXDE
Sequence: WIMGHMVNAIAQIDEFVNLGANSIETDVSFDDSANPEYTYHGVPCDCGRTCTKWEYFNEFLKGLRKATTPGDSKYHEKLVLVVFDLKTSSLYDNQASDAGKKLAKSLLQNYWNNGNNGGRAYIVLSIPNLAHYKLIAGFKETLTSEGHPELMDKVGYDFSGNDEIGDVAKTYKKAGVTGHVWQSDGITNCLLRGLDRVRKAVANRDSSNGYINKVYYWTVDKRATTRDALDAGVDGIMTNYPDVIAGVLNESAYKAKFRIASYDDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LdSicTox-alphaIB1avi, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MPRF_STAAS
Sequence: MNQEVKNKIFSILKITFATALFIFVVITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKMDISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILDKITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALSGLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTSFLMSYQKDIIAKIPSLSLAILVFFTSMIFFVNNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGQFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK
What is the function of this protein?
Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge.  LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Phosphatidylglycerol lysyltransferase, Lysylphosphatidylglycerol synthase, LPG synthase, Multiple peptide resistance factor.
What is the protein family that this protein belongs to?
Belongs to the LPG synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHBR_ECOLI
Sequence: MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDYYEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFEQHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRHYREEQVIDDVPQWLKSTVEKMHDKEQFSESALENMVALSAKSQEYLTRATQRYYGKTPMQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLTEFNQ
What is the function of this protein?
Dual-function repressor/activator of the chbBCARFG operon.  In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose.  In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon.
What are the official names of this protein?
HTH-type transcriptional regulator ChbR, Chb operon repressor.
Protein: KDNA_SHEON
Sequence: MPGFELFGPEEKQEVADVMEHGFTFRYNFDHMRNDRWKTRDMEQLLCEKMNVKHAHLLSSGTAALQTAMMAAGIGAGDEVIVPPFTFVASVEAIFMAGAVPIFAEIDETLCLSPEGIEAVITPRTKAINLVHMCGSMAKMDEIKAICKKHNLVLLEDACQAIGGSYKGQALGTIGDVGCYSFDSVKTITCGEGGAVITNNTEIYDNAHMFSDHGHDHIGKDRGAESHPIMGLNFRISEMNAALGLAQLRKLDTIIDIQRKNKKAIKDAMASIPEVSFREIPDPEGDSAGFLSFMLPTEARTQEISKKLAANGVDGCFYWYVNNWHYLKNWKHIQELKAPAALPITLIADRPDYTQISVPKSDAIMSRTISMLIKLSWTDAQIAERIENIKKAFAQ
What is the function of this protein?
Catalyzes the second (last) step of the biosynthesis of Kdo8N (8-amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno-octulosonate).
What are the official names of this protein?
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family.
Protein: SYR_SALA4
Sequence: MNIQALLSEKVSQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLSGIASKVEIAGPGFINIFLEPAFLAEQVQQALASERLGVSQPTRQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHHVIRANHVGDWGTQFGMLIAWLEKQQQENAGDMALADLEGFYRDAKKHYDEDEAFAERARNYVVKLQSGDAYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPDSVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKADIDEQALASAPVIISEDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDVAGLFSGFYEHCPILSAENDAVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_SALTO
Sequence: MVSATPPAPADGRRVALLTLGCARNEVDSEELAARLHSDGWQVTTDGEGADVVVVNTCGFVEKAKQDSIQTLLAAAETGAKVVAAGCMAERYGRELAESLPEAQAVLSFDDYPDISDRLGAVLAGTAIDAHTPRDRRELLPLTPVRRGEAAVSLPGHGTPAAVAQPGARSAPIEVDEHTPAHLRPVLRRRLDTGPVASLKLASGCDRRCAFCAIPAFRGAFVSRPPEALLAEAEWLARTGVRELVLVSENSSSYGKDLGDPRALEKLLPQLAAVDGIVRVRASYLQPAETRPGLVEAIATTPGVAPYFDLSFQHSSEAVLRRMRRFGSTDRFLELLGSIRALSPEAGARSNFIVGFPGETRADVAELVRFLEEARLDAIGVFDYSDEDGTEAAGLSGKVTTATVKRRYDRLSALADELCAQRAEQRLGSTVQVLVDSVDGGVVEGRAAHQAPEVDGSTTLVAPVGGGVDLTALRPGDLVECTVTATEGVDLVAVPDAMISAAPGVAR
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDOX_ALKCK
Sequence: MVIVANKTLIRKGEGHKLVKRFDKIGKIEMQKGFLGLEVLVNAKEKEVDEVTISTRWETKADFHAWTKSEAFREAHSGRNARPDYILGNEIEFYDVEVVRMPIAQAQ
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme-degrading monooxygenase, Heme oxygenase, Iron-regulated surface determinant, Iron-responsive surface determinant.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_SERP5
Sequence: MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGSGIGKDDLALALARHATSKISTLDDLEAIVSLGFRGEALASISSVSRLTLTSRTAEQNEAWQAYAEGRDQAVTVKPAAHPIGSTLEVLDLFYNTPARRKFMRTEKTEFGHIDEVVRRIALARFDVAINLSHNGKLMRQYRAAKDESQYERRLGSICGPAFLQHALNISWQHGDLTIRGWVADPAGARQLGEMQYCYVNSRMMRDRLINHAIRQAYQDQLKDDQQPAYVLYLEVDPHQVDVNVHPAKHEVRFHQARLVHDFIYQAVTTVLQQVGNAPLPLTDETEQQPTPVWQPENRVAAGGNHFSQPAPRRETASTEPAVARERAPQPAYHSGSGYQKREGELYGKLLQATPVAEPRQEAPKQPLFPPVKTEQETPLAGSQHSFGRVLMIYPPCYALIENGQQLMLLNLPVAERWLRQAQLNPSQEGLRPQPLLIPIKLTLNKQEAAACIHHQPLLVTMGLDLQVDHGRVTLRAVPLPLRQQNLQKLIPELLGYLAEHQEMSPAVLATWFARHLGSEHEQWNTSQAIQLLTDVERLCPQLVKSPPSGLLQPVDLQAALTALRHD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: YIDC2_LISMO
Sequence: MKKKKRFKQKLLIASLVIGLMAVLSGCGYSTDPITSESTGFWSHYIVFPLSWTITWFSDLFGGSYAVGIIVVTILIRLLIMPLMIKQLKSQKAMTNLQPKIKELQEKYSSKDNETKQKLQQETMRLYQENSVNPMMGCLPLLIQMPILLGFYQAISRTAEIKTDSFLWMQLGNPDPYYILPVVAALTTFLSSKISMMGQTQQNKSMAMIVYIMPVMILFMGITLPSALALYWIIGNIFTVFQTLLINNPFKNKREQEALAAAQVAEDRLKKKAANMKASKKGGKKRK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 2, Foldase YidC 2, Membrane integrase YidC 2, Membrane protein YidC 2.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.