PharMolix/UniProtQA huggingface dataset:
Protein: ERF1X_ARATH
Sequence: MGDKNDDDKNIEIWKIKKLIKSLEAARGNGTSMISLIMPPRDQVSRVTKMLGDEYGTASNIKSRVNRQSVLGAITSAQQRLKLYNRVPPNGLVLYTGTIVNEDGKEKKVTIDFEPFRPINASLYLCDNKFHTEALNELLESDDKFGFIVMDGNGTLFGTLSGNTREVLHKFSVDLPKKHGRGGQSALRFARLRMEKRHNYVRKTAELATQYYINPATSQPNVSGLILAGSADFKTELSQSDMFDPRLAAKILNVVDVSYGGENGFNQAIELSAEILANVKFIQEKRLIGKYFEEISQDTGKYVFGVEDTLNALESGAIETLIVWENLDINRYVMKNSATGETVIKHLNKEQEANTENFKVADSDLALDVEEKLSLLEWLANEYRRFGCALEFVTNKSQEGSQFCRGFGGIGGILRYQLDMTAFDSEDGEALDDDSE
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (PubMed:15474304).  Modulates plant growth and development (PubMed:16113224).
What are the official names of this protein?
Eukaryotic peptide chain release factor subunit 1-1, Eukaryotic release factor 1-1, eRF1-1, Omnipotent suppressor protein 1 homolog 1, SUP1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_STRMK
Sequence: MTRNDPSRTIAAPTGTTLNAKSWLTEAPLRMLMNNLHPDVAERPQELVVYGGIGRAARDWESFDAIVETLKRLDDDQTLLVQSGKPVGVFRTHADAPRVLIANSNLVPRWANWDHFNELDRKGLAMYGQMTAGSWIYIGAQGIVQGTYETFVEMGRQHFGGDLTGKWLFTGGLGGMGGAQPLAAVMAGASCLAVECRKSSIDMRLRTGYLDTWTDNLDEALRLIDESCKAGTPKSVGLLGNVADVLAELLKRGVKPDLLTDQTSAHDPVNGYLPQGWTVEQWDEKRVSAPKDVEKAARASMANHIRAMLGFHALGVPTVDYGNNLRQMALEEGVANAFDFPGFVPAYIRPLFCRGIGPFRWAALSGDPEDIAKTDAKVKELIPDNPHLHRWLDMAAEKIKFQGLPARICWVGLGDRDRLGLAFNEMVANGELKAPVVIGRDHLDSGSVASPNRETEAMADGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCDGTEAAAKRIGRVLWNDPATGVMRHADAGYDIAIDCAKEKGLDLPGILG
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_TAXTA
Sequence: MSMVYINIFLAFTLSFMGLLIYRSHLMSSLLCLEGMMLSLFVLMTVTILSNHFTLASMAPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PURA_RHILO
Sequence: MANVVVVGSQWGDEGKGKIVDWLSERADVVVRFQGGHNAGHTLVVDGKVYKLSLLPSGVVRQGKLSIIGNGVVFDPHAFVAEVAKLKAQGVEVTPDRLKIAENTALILSLHRELDGFREDAASNSGTKIGTTRRGIGPAYEDKVGRRAVRVMDLADLETLPLKVDRLLTHHNALRRGLGHGEVTHDAIMAELTSVADEILPYMDRVWKILDDKRRAGERILFEGAQGTLLDIDHGTYPFVTSSNTVAGQAAAGSGVGPGAIGYVLGITKAYTTRVGEGPFPTEQKNEIGEFLGTRGHEFGVVTGRKRRCGWFDAVLVRQAVAVNGIKGIALTKLDVLDGLDEIKVCTGYRLDGEMIDYLPASQGAQARVEPVYETLEGWKGTTAGARSWNDLPAQAVKYVRYIEELIGAPVALLSTSPERDDTILVTDPFQD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP3_USTMA
Sequence: MPKASASSAKMTASTSNVSSSNSKLKKSKASSPSASPEVSTPSTSNSNDDQDGHVSEDMSDAEEGESQEHSASGSGISDHDDDDDPSADKDSPAADEEQDEKKVATIADDGKKVEFSDLGVIPQIVEACTNMGFKHPTPIQVKAIPEALQARDVIGLAQTGSGKTAAFTIPILQALWDNPKPFFACVLAPTRELAYQISQQVEALGSTIGVRSATIVGGMDMMSQSIALSKRPHVIVATPGRLQDHLENTKGFSLRGLQYLVMDEADRLLDMDFGPIIDKLLQSIPRERRTMLFSATMTTKVAKLQRASLKNPVRVEVDTKYTTVSTLKQHYMFMPFAHKDTYLVHLANEQAGHSIIVFTRTVHDSQRLSILLRLLGFPAIPLHGQLSQQARLGALNKFKTGGRSILVATDVASRGLDIPAVDLVVNYDIPTNSKDYIHRVGRTARAGRSGRSVTLVTQYDVELLQRIEAVIGLKMTEFPGGNDKEAVMLLSERVAEAHRAAVRELKDKGVGSAGGSGKRKRKMDGKYGDDMDRDDDQVQAGLPVSGNGRHQNQNRKKGRR
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase RRP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_STRU0
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLTNWGTIQKRITRLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDVMYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITSKLADAIIEGRQGEDASVEFEADTKADSIEEIVEVVEGDNN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RPPH_BURO0
Sequence: MLDREGFRPNVGIILLNARNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLHPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRAEKPRGPRMSRYPRVIGAQAQTLTIVDTSVVCSEIEVEASTLDEMPPHVIVGK
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RK2A_SOYBN
Sequence: MAIHLYKTSTPSTRNGAVDSQVKSNPRNHLIYGQHRCGKGRNARGIITAGHRGGGHKRLYRKIDFRRNEKNIYGRIVTIEYDPNRNAYICLIHYGDGEKKYILHPRGAIIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNVGVNQKNLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPATPWGFPALGRRSRKRKKYSDNLILRRRTK
What are the official names of this protein?
50S ribosomal protein L2-A, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UBFL6_HUMAN
Sequence: MPAKDIKVALPRSQGHWSNADILRLLECMENNLPYDDNGTFSSTQSHMDWGKVAFKNFSGEMCRLKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEVTKILSKKYKELPEQMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQKGKKSDICKRVQTKVQKKVQKNIEEVRSLPKTDQFFKKVKFHGEPQKPPMNGYQKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHYKSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSSAKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEDNRKKDGEEEESSNSLDCSSGEDMEVDV
What are the official names of this protein?
Putative upstream-binding factor 1-like protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYE2_CAMJE
Sequence: MHEKLTTRFAPSPTGYLHIGGLRTALYNYLYARKNGGNFLLRIEDTDLKRNSKEATKAIIEAFKWCGLEHDGEVTYQSERFDLYKEYVKKLLDEGKAYYCYMSKEELEELRAKQEAAKERPRYDGRYREFTGTPPQGIEPVVRIKAPQSGEIVFEDGVKGEVRFKAEDIMDDFIIARSDGTPTYNFTVVIDDALMGVSDVIRGDDHLSNTPKQIVLYEALGFKIPKFFHVAMIHGEDGKKLSKRHGATDVMEYKEMGILPQALLNFLVRLGWSHGDDEVFSLEDLKKLFDPYHINKSASCYNAKKLEWLNAHYIKTLPFEEINRQLKDLGFDLSVYEKAGFLLDLLRERAKTLHDIINGAKSIVNAPQNYDENAVQKFVNKNNLELLQAFANTLKDQKTGKDFEDFTNDFLEKKEAKLKDLAQPIRIALTGSAVSPSIFEVLEFLGVDECKKRIDNFLKVRGK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_SHEPC
Sequence: MIGTPYTEGARRAMLLGCGELGKEVAIELQRLGVEVIGVDRYANAPAMQVAHRSHVINMLDAKALRAIIELEKPHLVIPEIEAIATQTLVEMEAEGVNIIPTARATKLTMDREGIRRLAAETLGLPTSPYFFCDTETEFNQAIREIGVPCVVKPVMSSSGKGQSVIRDIALSHKAWQYAQEGGRAGGGRVIVEGFVPFDYEITLLTVSAVNGIHFCAPIGHRQEDGDYRESWQPQAMSDEVLAKSQAIASKVVEALGGYGLFGVELFVKGHEVYFSEVSPRPHDTGLVTLISQDLSEFALHVRAILGLPIPNIHQHGPSASAVILAEGTSSNIRYQGIGAALEAVNTQLRLFAKPDIDGRRRLGVALARDIDIDSAISKALDSASKVKVIF
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: QUEG_LEAB4
Sequence: MRDYSKEIKSWAAELGFDFCGISAADFLEEEAPRLERWLNRNYHGKMAYMANHFDKRLDPRKLVDGAKSVVSLLLNYYPEEPLDASPYKISKYAYGKDYHYVIKDKLKLLFERIQKEIGEVGGRIFVDSAPVMDKIWAKKAGLGWVGKNSNLINRKMGSFFFIAELILDLPLQADGPIRDYCGTCTACIDACPTDAITPYEVDGSKCISYLTIELKDQIPNEFKGKMENWIFGCDICQDVCPWNSFARPHSTEEFYPNENLKTFQDWDEITSEIFSHLFKKSAVERTKLEGLKRNIAFVKEV
What is the function of this protein?
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
What are the official names of this protein?
Epoxyqueuosine reductase, Queuosine biosynthesis protein QueG.
What is the protein family that this protein belongs to?
Belongs to the QueG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAP4_YEAST
Sequence: MSLWPFGETLSHSGIDSILEEYYLIFRSLEGNETSSTDDKKNEPSMESESEFGTESRDRSDLNQSFIDRILLETALLDELNGAANDRLVDFICLGYFYDDRSQQVRHMDYLVDMLMAYLKDIDRTGYRTPFLLENSFHQTGEYEDQDDEDPMLYVNIISSIFCSKSAPIVEALVQNTPFLSSLFEVFQFENIEAENCPILAVFLKINETLLFEQTSSYLEFFKSQPNIVDKFLYHIEVSPLVEFLIKIMLTDQVESPTNIIDFLYHQDLIPKCLNLLENSKYSPGIQNSSGELLKALISISTNFKLDTLWIGPNRLTRQLASPQYVDQLINIILFQRGHAMGVAVSIIIELIRKNNSDYDEVDLLSTTIVDNPPSQRDPVYLGHLLYELTMHMEDFYALLIKLENDDDDDHDTASKALPSVKHHLLENQLHESFRPLGFERVKITELISEMLHCSNMGLMNSKRGEKIARTRDKCRDTLDQNSLEKAMKNLNINDNTITSNTLEDKCNNNDSNDSNDNQKQKKNIKKKFHDNELYSTFDTSDDNIDDDDDMSFEIPYVSETQNLKIRKNPTIGDLFKIKLHDLGFFPKFLQLFLRYPWNNFWHNIVFDIIQQIFNGRMDFSYNSFLVYSLFDFKKSTRFIPKPLYGSNQKLPVKDFHIISDFILQGHKDSFEFYEKEKTNLGYMGQLVLIAEEIAKYSKIYKTDLIAPDIYAFLQDEVWMSYSSDILNETRTMCSIILGGGQFCAESDENTNQDFLEKADMSKPAHPSTMDENEIVHEEDVKLHDKVAELIDELGQLTELDIHDKIKDVIVDHHSDLN
What is the function of this protein?
Associates with the SIT4 phosphatase in a cell cycle dependent manner.  May be directly or indirectly involved in SIT4-dependent functions in budding and in normal G1 cyclin expression (By similarity).
What are the official names of this protein?
SIT4-associating protein SAP4.
What is the protein family that this protein belongs to?
Belongs to the SAPS family.
Protein: SLYX_SODGM
Sequence: MELSQLEQRLEVLEGRVAFQEVTIEELNQTVVAHQRDISRLQEQLRLLSDKLREQNTSIIASQSEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: ENO_LATSS
Sequence: MSIITDILGREVLDSRGNPTVEVEVYTEDGGFGRAIVPSGASTGEHEAVELRDGDKSRFGGKGVLKAVENVNGPLAKEIVGFDTTDQRGIDAAMIKLDGTENKGKLGANAILGVSLAAARAAADELGLPLYEYLGGPNAHVLPTPMMNVINGGAHSDNKVDFQEFMIMPVGAKSVREAIRMGSETFQALKSLLSADGKVTSVGDEGGFAPDFANNEEPLQYLIKAIEKAGYKAGEDISIAIDVASSELWNNEDKTYKLRWSTGEEFTTPEFVKYLEGLVAKYPIISIEDPIDENNWEDWASITKELGEKVQLVGDDFFVTNTDYLRKGIKMGAANSILVKVNQIGTLTESLEAIEMAKEAGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRLAKYNQLMRIEEQLGDTASYKGINSFYNIKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: EAF1_CRYNB
Sequence: MRHVRAMERIEAKKAENRWSLRQPKKARGPGVPKSHWDYMLEEMEWMRTDFAEERRWKVVEAREFAYQVVEWHLASPEEKKALMVGGRGWGECRNVPIPGHAGKRKEVTVEVEAEDEDVEMLVGQEGELDGEGEANKVLESIDEMRVNEKERENRPEDPRETVNINQDIGEEVDAEGEADADGEPENGEADAEGEADADGGPVGDDVVGLSEIDAAQDDTRETSERPSYRRDTVLPNGLVIHKRFANAYEIAIARGPVLDTPLANATVDLDTLTKSSSAATPATVPAEPSVSPDEPASFDQLFPDLAMYSGPAPPENDKKYRRDEGGTYSHRMAHTSRIMDIRPILVSTLQPAKNLIDGEWDLHDGPYYEEVKGAADIPPNVVAAFNTPFGGKASRPLEHMRVPEVPKPAAHHLRAQLLWSPEEDKCLLKLVAMYPFNWDLIADSFNTEMILIPVEKRNPYECWERWYYTFGEGKNKPRQDAPPSAPPPAPASATQPGTATATPVPQSAVTTPGVPPSANLPSASGRPQQTGGNSVSSLPTPTGEALPDGAPPPPGMSKRDRMAAKPKYEGTKRSVRHQAIYDAVKRMNRRREAARAKSHKDNAQRKVINVHESHSMSFPHVAASTPWELVEAKYQRDVQIAQQRQQRAMQEQQRQLAIRQQQAMMSAQQQAQMRPPNMPNVPNMPNAQPIRMGPNGQPMPTMAPSQQQLLNAVAAATAANRQNANGAVQGNPNVRPMPVVQGQSPQVQQQMLLQAQQMAAQQARVLQAQAQAQAQQGRAPSMGGNLQPPQLGVSSPFAQSRTPDLPAEGAGPSGINPTPSPAMQAAAIGAQSSPQIATMGRAPSNNVPPHLRVPNAGTSSPQISSPMALPQGIPNGAGMPVQGAQTQGIQIPAAMMNNATVQQLLATLAASGQQMTPEQLRGLMLRSAHMQAQAQSQVGNPGTPQMGVQNIQGVQHFARSPSLQNAQSQPRSSPKPGPANGQGT
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF1, ESA1-associated factor 1, Vacuolar import and degradation protein 21.
What is the protein family that this protein belongs to?
Belongs to the EAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KEX1_CRYGW
Sequence: MSGNDARARVRSLPSTSSPLETRDSDEQESSSSQSQRGSRKRGPQRRATELPSAADLYVPSLPGLPDMATHPTHPLNIYAGMLPSYPGEGKVGGEGETGKDAKLYFLMAKARRNAGKERVIFWFNGGPGCSSFDGSLMEVGPFRTVPASETTTGMVEAKLVEGGWEEFATVVFVDQPPGTGYSYAATNGYLHDFDELSAHFIEFLQNFYTVFPELKGVDTYLAGESFAGQYIPFFADALINSAELPNFPLKGIAIGNGWIDPKEQYPGYVEFAYEKGLIDSGTPVSAAFVDLHKERADQMLTDQEAEEMEAALKRCQEEMDKYTDPFTTPVNIDHCGEVMDSVTRPFTQELNGKKVCMNVYDVRLVDDFPACGMNWPPDLPDVYTFLRQDEVISALHASSKETAWVECNNKVSYELNLKHSHMSAALLPSILEAGVPILMFAGAEDLICNYKGIERIVNGLEWGGEKGFANATSQEWYLNGTQVGTWQTSRGLSYAKIFDSSHMVGFDVPHVTNDMIMRFMDVDVSLLPGMISQWSSRIGDDERTMIHVGDAGEAGGVPLIKGGNTDWEAWYNAVFAFLVLGILVSIVGLYFYFRRKPVSYRSRIALKQRGRHRQSHDRDEGDTAERMPLGSERLELDDIERAEGYEFDDRDDEGYSGKGKGKGKELADDREEVMFALGDDDEDDRH
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: BTUF_YERP3
Sequence: MMPLGLFPLPRAAVVLLISLLTLPAQAAERVISLSPSTTELAYAAGLGDKLVAVSAYSDYPESAKKLEHVASWQGINVERILALKPDLILAWRGGNPQRPLDQLAALGIPIFYSDPTHIDQIASDLDKLAQYSPHPEQAHQAAEQFRQHVNTLRDRYARSQPKRTFLQFGTQPLFTSSGHTLQSEVVSLCGGENIFADSRVPWPQVSREQVMTRKPQVIVVSGTQSQVDNVSAFWLPQLVVPVIALNEDWFNRASPRILLAAQQLCQQMASIPTPVAESH
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ACDH2_RHOE4
Sequence: MSKVKVAIIGSGNIGTDLMIKVLRNSDYLEMGAMVGIDPASDGLARAARLNVPITAEGVEGLIGLPNFDEIEIVFDATSAKAHVANNARLAPLGKRMIDLTPAAIGPYVVPAVNADEHLDAPNVNMVTCGGQATIPMVAAVSRVVPVAYAEIVASIASKSAGPGTRANIDEFTETTSEAIVAVGGARRGKAIIILNPAEPPLIMRDTVFCLVDAPDPAVHEEIRQSIEKMVGDVSAYVPGYRLKQEVQITEIPADQPVETLLVDGNRPTHQVSVFLEVEGAAHYLPAYAGNLDIMTSAGMQIAERIAQQKEATK
What are the official names of this protein?
Acetaldehyde dehydrogenase 2, Acetaldehyde dehydrogenase [acetylating] 2.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: CSN1_CAEEL
Sequence: MQNELLDDPMDTGAPAAEAAAADEPLPPAHGIDREVTPKPAGNPDLMQQSLDNPAIPMHLIEKRDDRRESCDDGYSLTVNESAIDIESLACSYDSNAFFLRARFIARHCPILRADAYISLINYLKEHTTDITHYVAFFNELESELARKEFKNRQLNFQIPLRDQKWIEENGATWQSTTDQLQAEYKRHKDEGVKESTRRAMEDLFQHYMMAGKIDEAIRLYSRGIRDYCTQLKHSINMWINWMEVAICANDWGKLDTVTNTAYRSLKDADDAEKNSQQSQQAPPQRGENAPYMVERDPNAPIQTLTNRQLIETALAKCLAAQVLLKLRNKRYSQVVETILQIKTECLQSKWFVTSSDLGIYGMLSAMATMSRADLKLQVSGNGTFRKLLESEPQLIELLGSYTSSRFGRCFEIMRSVKPRLLLDPFISRNVDELFEKIRQKCVLQYLQPYSTIKMATMAEAVGMSSAELQLSLLELIEQKHVSLKIDQNEGIVRILDERDENAILKRVNVTCDRATQKAKSLLWKTTLAGANIHSISDKETRPKRKNQKESAKFDRNFGGIDVDEDPRGIAGPSGLSDDFNIAYDQQPQQQVQYLEDLGDI
What is the function of this protein?
Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo.  Mediates mei-3/katanin targeting for degradation at the meiosis to mitosis transition via deneddylation of cul-3.
What are the official names of this protein?
COP9 signalosome complex subunit 1, Signalosome subunit 1.
What is the protein family that this protein belongs to?
Belongs to the CSN1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYY_LEPIN
Sequence: MDIQKQIEIIRRGTVDLISEEELKSKLQKKKTLKIKAGFDPTAPDLHLGHFVQLKKLKHFQDLGHEVSFLLGDFTAMIGDPTGKSETRKRLSREEVLENSKTYQNQVFKVLDPVKTKIVYNSNWCSKMNFEDVLVLSSKYNVARMLERDDFSKRYKAGQPISMIEFLYPLVQGYDSVAMECDVELGGTDQKFNLLVGRDLQREYGKEAQCVLTLPLLVGLDGSKKMSKSLGNYVGITETPIDMFGKLMSISDDLMWNYFELLTDLPLPEIENRKNGMAKKELHPKEIKTELAKLIMDQFSSPSENEEAIQEWKKIHNPKSRAVPDDVKEIKLGEEFFAETPEPLLVWVLSKLSFIPSVSEGRRLIKAGGLYLSEDKITDEKFPIQKGKEYLVRQGKKGKFLKIIS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XRN2_KLULA
Sequence: MGVPSFFRWLSRKYPKIISPVLEEYPVIEDGVQLPLDYSSANPNGELDNLYLDMNGIVHPCSHPENKPPPETEDEMLLAVFEYTNRVLNMARPRKVLMIAVDGVAPRAKMNQQRARRFRSARDAKLQNEAREQVLREREDYGETIDENVKSKKTWDSNAITPGTPFMDKLATALRYWTSFKLATDPGWKNLQIIISDATVPGEGEHKIMNFIRSQRADTQYNPNTTHCIYGLDADLIFLGLATHEPHFKILREDVFANNNYKKPKPQDMINLSEEEKQQLIQQDSEKPFLWLHISVLREYLSAELAIPHLSFQFDFERAIDDWVFMCFFCGNDFLPHLPCLDVRENSIDILVDIWKTVLPKTKTYLTCDGTLNLEPVEALLEQLGDRETDLFKKKYIQEVRKQEAHDRRKKLKSNPNVSQGKVDRNFMIPLENMPVYDVDGNAAEGSLNLSNKDFANMRKEINLANEGDGEAAKALKLKSEKNSGVVEFSSEELKNSVQLSKTANYDAATSLQEKLIAKKMAMRDEENAEELSLKRKSEDVDSAEKETSNEPEDDEADYDEDEGSTVPPAVIHTGIVKSGFIDTDESVRLYEPGYHDRYYQHKFHVPAKDIPALQKDVIRCYVEGISWVLLYYYQGCASWTWYYPYHYAPFAQDFKNIKNLDIHFDLGEPFLPYEQLMSVLPAASGHALPEIFRPLMSDPNSEIIDFYPEEFPVDMNGKKMAWQGIALLPFIDETRLLKTVREQYSKLSDSEKARNVRKKDALLISNKNVNYDLFMKNLYGENPVNVIEFRHFKSGLSGFVTQAEEGFELNSKLICPINGGGLPDLSTNLFLKLSYTQPVVAGRCKSLVLNGYIPPQPMLTPQDRDCIIYKYSNRWNPSMMKYNIVPVGPSGITQYQPRVGGYRSFFFHKEQTAYAQQPQQNREYMHSQQRQPQGSRYQQSRYNNGNYNNSNNGYSDNNNGNTGKYNRHYNNSRGNSNRYSNSNDRRREFRR
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity.  Required for the processing of nuclear mRNA and rRNA precursors.  May promote termination of transcription by RNA polymerase II (By similarity).
What are the official names of this protein?
5'-3' exoribonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HGPRT_RHOCB
Sequence: MSQSGYVIDQMISAKAIAARVEALGAEITEAFKDTDRLVVVGLLRGSFVFIADLIREIGVPCEVDFLEASSYGNETTSTREVRVLKDLRGIIGGRDVLVVEDIIDTGHTISKVMEMLRARAPRRIECCAMLDKPSRREVDVKARWTGFEIPDEFVVGYGLDYAQNHRNLPFIGTVRFTDPQK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENDO2_BPT5
Sequence: MGKKITKQDRESQISNICNDKNLSFVGWIGEYTNIKSTLTLKCNKCYYTWSPRLDNFLRITAQKCPACAGKARWTKEEREEQIKSKCAEKGYNFLSWSSTYINKDSKIILKCLKDGCIWDVSIHHFINHDTGCPDCASGGFNPNIPATFYIQKLTYQGTHFLKFGITGKDVLERMRQQSNKSLCEHSVIFSHTFSYGSMARGLEKVVKDSVNTGVLDKRILPDGYTETCHYSELETILSLTNSFIQENIR
What is the function of this protein?
Putative endonuclease.
What are the official names of this protein?
Putative endonuclease.
Protein: MNMC_VIBCM
Sequence: MFIMSSISHAQLGWNDAGTPVSDQFDDVYFSNVNGLAETRYVFLEQNHLPQRWHNDDQRRFVIAETGFGTGLNFLAVWQAFVAFREANPDAKLKELHFISFEKYPLSKSDLIQAHQAWPELAQFAQKLHKHYPLAIPECQRIVLNDGLVTLDLWFGDIKDCLPKVATQEQGLVDAWFLDGFAPSKNPEMWNQNLFAGMAKLAKHGCTCATFTSAGFVRRGLIDAGFAMKKVKGFGTKREMIAGSLSEKVPYTNIAPEFRFEATHGLQEVAIIGGGIASATLATTLARRGVAVTLYCADEKPAQGASGNRQGAVYPLLSGDHNAVSRVFAPAFLFARQWIEQAAEQINFDHDWCGVTQLMWDEKATDKLKSMLEGNFPTQLVHGLSAEQTNQQVGVPVDKASVHYPLGGWLSPAELTQGLIHLLEQQGKLTAHYQTPIDALTWQPETQLWQLRSGDTLMSHQCVVIASGHQFDSLSQTAELPLGKVKGQVSHIPTTETLSKINSVLCYDGYMTPVSQQNGYHCIGASYDRQHLDATFDPQAQHENAQKLIHCLPEQTWPLEVDVSGNQSRQGVRCVSRDHLPFVGNVGEFSKITEQYRDLAQQHQAEPIALYPQLYALVGLGSRGLSSAPLMAELLASQMCGDPMPLGVDLLEQLHPSRMWVRKLRKGKALTQKV
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.