PharMolix/UniProtQA huggingface dataset:
Protein: SURE_MANSM
Sequence: MNILLSNDDGYHAEGIQILARELRKFADVTIVAPDRNRSAASGSLTLVEPLRPRHLDDGDYCVNGTPADCVHLALNGFLSGRMDLVVSGINAGVNLGDDVIYSGTVAAALEGRHLGLPSIAVSLDGRRYYETAARVVCDLIPKLHTRLLNPREIININVPDIPYDQIKGIKVCRLGHRAASAEVIKQQDPRGESIYWIGPAALPEDDEEGTDFHAVNNGYVAITPIQVDMTSYNSMSALQDWLESE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ONCO_RAT
Sequence: MSITDILSAEDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADEFQEMVHS
What is the function of this protein?
Has some calmodulin-like activity with respect to enzyme activation and growth regulation.  Binds two calcium ions.
What are the official names of this protein?
Oncomodulin, OM, Parvalbumin beta.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: RS5_CHLMU
Sequence: MTLSRNSHKEDQLEEKVLVVNRCCKVVKGGRKFSFSALILVGDRKGRLGFGFAKANELTDAIRKGGDAARKNLVSINSLEGGSIPHEVLVNHDGAELLLKPAKPGTGIVAGSRIRLILEMAGVKDIVAKSLGSNNPMNQVKAAFKALLTLSCKDDIMKRRAVIND
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: THIL_RAT
Sequence: MAALAVLHGVVRRPLLRGLLQEVRCLGRSYASKPTLNDVVIVSATRTPIGSFLGSLASQPATKLGTIAIQGAIEKAGIPKEEVKEVYMGNVIQGGEGQAPTRQATLGAGLPIATPCTTVNKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMSRGATPYGGVKLEDLIVKDGLTDVYNKIHMGNCAENTAKKLSISREEQDKYAIGSYTRSKEAWDAGKFANEITPITISVKGKPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAAVVLMTAEAAQRLKVKPLARIAAFADAAVDPIDFPLAPAYAVPKVLKYAGLKKEDIAMWEVNEAFSVVVLANIKMLEIDPQKVNVHGGAVSLGHPIGMSGARIVVHLAHALKQGEFGLASICNGGGGASAVLIEKL
What is the function of this protein?
This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA.  Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms.  The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA.  Thereby, it plays a major role in ketone body metabolism.
What are the official names of this protein?
Acetyl-CoA acetyltransferase, mitochondrial, Acetoacetyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HCHA_STAA2
Sequence: MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVADLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSA2_HUMAN
Sequence: MPQNEYIELHRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKNDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May play a part in the quality control of pre-60S particles (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein NSA2 homolog, Hairy cell leukemia protein 1, TGF-beta-inducible nuclear protein 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DRD4_HUMAN
Sequence: MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
What is the function of this protein?
Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior.  Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs (PubMed:9003072, PubMed:16423344, PubMed:27659709, PubMed:29051383).  Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase (PubMed:7512953, PubMed:7643093, PubMed:16423344, PubMed:27659709, PubMed:29051383).  Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).
What are the official names of this protein?
D(4) dopamine receptor, D(2C) dopamine receptor, Dopamine D4 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENO_YERE8
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVAAVNGPIAQAVIGKDAKDQANIDKIMIDLDGTENKSQFGANAILAVSLAAAKAAAASKGMPLYEHIAELNGTPGKFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEAVRIGSEVFHTLAKVLKAKGMSTAVGDEGGYAPNLGSNAEALAVIAEAVKQAGYELGKDVTLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEDLTKQYPIVSIEDGLDESDWAGFKYQTEVLGDKIQLVGDDLFVTNTKILKEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGDRAPFNGLKEVKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: NIT2_PONAB
Sequence: MASFRLALIQLQISSINSDNVTRACSFIREAATQGAKIVSLPECFNSPYGTKYFPEYAEKIPGESTQKLSEVAKECSIYLIGGSIPEEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSPGDSFCTFDTYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQRGRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKKP
What is the function of this protein?
Has omega-amidase activity.  The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively.
What are the official names of this protein?
Omega-amidase NIT2, Nitrilase homolog 2.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP_SHIBS
Sequence: MIMFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVSAYDDRIWTRSIVGWPGVRHLDGDDFSAVITQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATIVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSHB_SYNY3
Sequence: MKLAFIIDPLEKLDPGHDSTVAIMEAAQKLGHEVFVTSVGDLAVINGQAWAKLAAVRLQPVILVDGHWQVSQPWSELSKSQWMALTECQAVFMRKDPPVTVQYLYATFILELLAPTKTMVINSPQGLREANEKMYTLQFAAVMPPTVVSLDKGLIRQFLEEHGAAVLKPLGGKAGEGILFLDPGDRNFNSLVEISTQHGKEPVMVQRFLPEAKEGDKRIILLDGDPIGAVNRIPSGAEFRGNMAVGGQVAPTTITSREIEICALLKPKLQADGLYFVGIDVIGGYLTEVNVTSPTGIREIDRLEGVRLGEKVICWLEKQF
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: VE1_PCPV1
Sequence: MADNTGTDNKGTGCSGWFLVEAIVDRKTGEEISDDEDETVEDSGLDMVDFIDDRCITHNSLEAQALLNEQEADAHYAAVQDLKRKYLGSPYVSPLGHIEQSVECDISPRLNAIQLSRKPKKVKRRLFQSREITDSGYGHTEVEVEAATQVERHGEPENGCGGGGHGRDKEGEGQVHTEVHTESEIEHHTGTTRVLELLKCKDIRATLHGKFKQCYGLSFTDLIRQFKSNKTTCEDWVVAAFGVHHSVSEAFEKLIQPLTIYRHIQWLTNEWGMLLLVLLRFKVNKNRCTVARTLATLLNIPEDHMLIEPPKIQSSVAALYWFRTSLSNASIVTGETPEWIARQTIVEHGLADSQFKLTEMVQWAYDNDYCDECDIAFEYAKRADFDSNAKAFLNSNCQAKYVKDCATMCKHYKNAEMKKMTMNQWIKHRSKKIDETGNWKPIVQFLRHQNIEFISFLSKLKLWLQGTPKKNCIAIVGPPDTGKSMFCMSLIKFLGGTVISYVNSSSHFWLQPLCNTKVALLDDATHSCWGYMDTYMRNLLDGNPMSIDRKHKSLALIKCPPLLVTSNIDITTEEKYKYLYSRVTVFKFPNPFPFDRNGNAVYELCDANWKCFFARLSASLDIQDSEDEDDGDTSQAFRCVPGTVVRTV
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: ASSY_CLOBB
Sequence: MNKLNKVILAYSGGLDTSIIIPWLKENYNCEVIAVCGNVGQKDELDGLEEKAIKTGASKLYIEDLTKEFVEDYIFPTIQAGAIYEGKYLLGTSFARPLIGKRLVEIAKAEGADAICHGCTGKGNDQVRFELAVKAFDPDMKIIAPWRIWDIKSREDEIAYAEARNVPIKINHETNYSKDKNIWHLSHEGLDLEDPKNEPKYDEILELSNSLEKAPNEPTYITLTFEKGNAVALNGEKMDAVTLLDELNKIGGKNAIGITDMVENRLVGMKSRGVYETPGGTILYKAHKDLEELCLDKETSHYKEQISLKFADLVYNGLWFTPLREALSEFIKKTQETVTGEIKLKLYKGNIVNAGMTSPYSLYSEEYATFGEDAVYNQNDSAGFITLYGLPTVVKAKMYQSLKKGTK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPT_SALPC
Sequence: MDKLLERFLHYVSLDTQSKSGVRQVPSTEGQWKLLRLLKQQLEEMGLVNITLSEKGTLMATLPANVEGDIPAIGFISHVDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGVAEIMTALAVLKGNPIPHGEINVAFTPDEEVGKGAKHFDVEAFGAQWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADEAPETTEGYEGFYHLASMKGTVDRAEMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCHITPEMKPIRGGTDGVQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRIAELTAKRGQ
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEB_SERP5
Sequence: MSTLGHKSDNSLVSNAFGFLRFPLNFMPYDSDAEWVITGIPFDMATSGRAGGRHGPAAIRQVSTNLAWEGNRWPWNFDLRDRVNVVDCGDIVFNFGDAQSMSDNLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGSQYDHGTMFFHAPNEGLIDPTHSVQIGIRTEYDHDNGFTVLDAAQVNDRSADDLLAQIKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRALKLVRGMQSLNIVGMDVVEVAPAYDQSEITALAAATLGLEMLYLQAAKKTK
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: TRMN6_YERPB
Sequence: MVTNVGEQLKKQPVLRGGGFTFKQFFVAHDRCAMKVGTDGVLLGAWVPVLHARRVLDIGCGSGLIALMIAQRSLPQVQIDGVELEPAAAQQASSNVELSPWAERIHIHQQDIHQFAENHPHQYDLIVSNPPYFAPAIACRDEARDTARYTGSLTHDALLNCAEKLITEDGMFCVVLPHELGIEFARLAGQQGWFVRCQVDIRDRPGKPLHRMLLTLSRQAGETVYQHLALRQSEGVYSPEFCQLISDFYLNY
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTR1_METJA
Sequence: MLDRIDLKILRILNGNARKSFREIGRELGISEGTVRNRVKRLTEKGIITGFHASINPKNLGFEVVAILGLYIKPSKVEETLNKLKELDEIVELYQTTGEYDAVCIAILKDIESLGKFLAEKIYPLVNVNGCKVTLVLRTFKDGSKMPI
What is the function of this protein?
Participates in positive as well as negative regulation of transcription.  Binds to its own promoter.
What are the official names of this protein?
HTH-type transcriptional regulator Ptr1.
Protein: RPOC_STAAU
Sequence: MIDVNNFHYMKIGLASPEKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFGPTKDWECSCGKYKRVRYKGMVCDRCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRALEEVIYFASYVVVDPGPTGLEKKTLLSEAEFRDYYDKYPGQFVAKMGAEGIKDLLEEIDLDEELKLLRDELESATGQRLTRAIKRLEVVESFRNSGNKPSWMILDVLPIIPPEIRPMAQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIAVGPSLKMYQCGLPKEMALELFKPFVMKELVQREIATNIKNAKSKIERMDDEVWDVLEEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVTTAYNADFDGDQMAVHVPLSKEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLERKDAVNTGAIFNNTNEVLKAYANGFVHLHTRIGVHASSFNNPTFTEEQNKKILATSVGKIIFNEIIPDSFAYINEPTQENLERKTPNRNFIDPTTLGEGGLKEYFENEELIEPFNKKFLGNIIAEVFNRFSITDTSMMLDRMKDLGFKFSSKAGITVGVADIVVLPDKQQILDEHEKLVDRITKQFNRGLITEEERYNAVVEIWTDAKDQIQGELMQSLDKTNPIFMMSDSGARGNASNFTQLAGMRGLMAAPSGKIIELPITSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIVREEDCGTDRGLLVSDIKEGTEMIEPFIERIEGRYSKETIRHPETDEIIIRPDELITPEIAKKITDAGIEQMYIRSAFTCNARHGVCEKCYGKNLATGEKVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEARNPKGQAVITEIEGVVEDIKLAKDRQQEIVVKGANETRSYLASGTSRIIVEIGQPVQRGEVLTEGSIEPKNYLSVAGLNATESYLLKEVQK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RGS5_RAT
Sequence: MCKGLAALPHSCLERAKEIKIKLGILLQKPDSAVDLVIPYNEKPEKPAKAHKPSLEEVLQWRQSLDKLLQSNYGFASFKSFLKSEFSEENLEFWVACENYKKIKSPIKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSPHSFDLAQKRIYALMEKDSLPRFVRSEFYKELIN
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 5, RGS5.
What are the subcellular locations of this protein?
Cytoplasm. Membrane.
Protein: T214B_MARPO
Sequence: MILISQAYVFNKIWEIKTKNKSYLKCLLKYWTSHLWIKKNFQSFLSNQGIVGSLELQNFKEENWKEWLKGFNRYNFSSKEWYKITPQQWRNKVSEHWKNQENKKLNPNQQISKNNFFINTSILEQTKKRNKIFKQNLLTYSCFDFTKNLAIRNFLNLNRKKIYNNIIINKIQKSYFIYNKKAKYLDFFSQKQNIFFEYNLLLWLIPEFIEEKNQYQNKRILILKNSIIKENNKKIIQNQKLFRKRELNQSIRQWRWKSKSLEKKFKKLGNMASLMTFMQNQENIISLSSKMREDLKLFHLFFRRNTTINQLTINSEHRLARLLDDQILMYKMVSTFLNIKYRFKRLSNLDNFDDFLGIQFFENKEKNNFFFFNSFNLEDILLPKRRRKFRILNSLTSKNKKNTQLNQKFVQKKFSKTKIKKIKRFIWASYRFEDLACMNRFWFNTINGSRFSMLRFRMYPSLLT
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Putative protein TIC 214 C-terminal part, ORF 464, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PNP_ALCBS
Sequence: MFNKITKQIQFGRDTVTLETGQIARQATAAVMVRIGDTQVLVTVVGRKEANPGQNFFPLTVNYQEKTYATGRIPGGFLKREGRPSEKETLTCRLIDRPIRPLFPKGFMNEVQVVATVMSSDKNRDPDIAALIGTSAALSISGIPFSGPIGAARVGYKDGMYILNPSYSELAESALDLVVAGTEPAVLMVESEAQELSEDQMLGAVLFGHMEMQPLIQGIKEFAAEVGTETWDWKPAEQNETLKAAIKDKFAAALGEAYTITEKMARYAKVGELRDACVAEFATGEDGAPEADEVKDLFGKIEKSVVREAVVSGKPRIDGRALDAVRAIDCQVGTLAKTHGSALFTRGETQAIVTATLGGMRDAQFIDALEGSHQDHFMLQYNFPPYCVGETGFIGSPKRREIGHGRLARRGVEAVVPSVQDFPYTIRVVSEITESNGSSSMASVCGTSMALMDAGVPLTAPVAGIAMGLVKEEDGRYAVLSDILGDEDHLGDMDFKVAGTARGVTALQMDIKIEGITEEIMEKALNQANAGRLHILGEMNKAIAESRSEVSDNAPTLLTLKINPDKIRDVIGKGGATIRALTEETGCTIDIEDDGSVKIYGETREKADEAVRRVEEITAEAEVGAIYEGKVTRVVDFGAFVAIMPGTEGLLHISQIAEERVEKVTDYVNEGEIIKVKVLDVDQRGRIKLSMKEAKED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_VIBVU
Sequence: MTELKNDRYLRALLKEPVDCTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELASEVTLQPLRRFPLDAAILFSDILTIPDAMGLGLRFSTGEGPIFDNPITCKADVEKIGVPDPEGELQYVMNAVRQIRKDLNGDVPLIGFSGSPWTLATYMVEGGSSKAFTKIKKMMYAEPQTLHLLLDKLADSVIEYLNAQIKAGAQSVMVFDTWGGVLTPRDYNLFSLQYMHKIVDGLIRENDGRRVPVTLFTKNGGMWLEQIAATGCDAVGLDWTINIADAKARVGDKVALQGNMDPSMLYASHDRIREEVASILEGFGHGGTGHVFNLGHGIHLDVPPENAGVFVEAVHELSKPYHQ
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_THEP3
Sequence: MKNIVLTGFMATGKTTVGKKVATNMSFGFIDTDKMIEKMANMTVSDIFEKYGEDYFRRLEKAAVIKAARLKNFVIATGGGVVLNPSNIVQLRKNGVVICFVARPEIILRNIGKNKDRPLLMVDNPEEKIRQLLKEREPFYRFADYTIDVSDMTIDEVAEEVIKAYIRLKKG
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB9B_MOUSE
Sequence: MSGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPDHFPFVVLGNKVDKEDRQVTTEEAQAWCMENGNYPYLETSAKDDTNVTVAFEEAVRQVLAVEEQLEHCMLGHTIDLNSGSKASSSCC
What is the function of this protein?
Involved in the transport of proteins between the endosomes and the trans Golgi network.
What are the official names of this protein?
Ras-related protein Rab-9B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or Mycobacterium.
Protein: OMPX_CHLTR
Sequence: MKKTKKRKQSITLVEMMVVITLIGIIGGALAFNMRGSLQKGKIFQTEQNCARVYDVLMMEYASGNLSLKEVIANKEAILEDSAWCKEGKKLLKDAWGEDLLVKMNDKGDDIVVFSKKVRNEQRG
What are the official names of this protein?
Putative outer membrane protein CT_569.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: MAD2_CANAL
Sequence: MPSSLEPSSKLALKGSSKIVCDYFEFALNSILYQRGIYPQEDFVTVKKYDLPMVINDDYDVQKYINNIMKQIKKWIYGSLMSKFIIVIVSKTNLENIERWEFNIETKDQEETTENGDGDGDGVGKSRQEIQKEIRTIIRQITSSVSYLPVLKDDDEYTFNVLVYTDPNTSVPIEWCDTQGDGKVLDGDNVDNVKFTSFSTDIHQVGTSVSYKYE
What is the function of this protein?
Central component of the spindle assembly checkpoint which is a feedback control that prevents cells with incompletely assembled spindles from leaving mitosis.  Plays a key role in virulence, probably through cell cycle checkpoint functions, especially those monitoring the integrity of DNA and chromosome segregation, which might be required for the pathogen to repair damage caused by host defense.
What are the official names of this protein?
Spindle assembly checkpoint component MAD2.
What is the protein family that this protein belongs to?
Belongs to the MAD2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYAY_ECOLU
Sequence: MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGETVSFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.