PharMolix/UniProtQA huggingface dataset:
Protein: MNMA_MYCGE
Sequence: MSIIAKTVFIGLSGGVDSAVSALLLKKQYQEVIGVFMECWDETLNNDFYGHKKINNNKSGCSSFQDFQQAKKIANSLGIKLIKKNLIEAYWNKVFLPMIQSFKKGLTPNPDIWCNRFIKFGLLHDFCKQINPNSLFATGHYAKINMIENQPLLSIPKDTNKDQTYFLANVKKEQFQNVIFPLADLKKITVRNIARENNWEVADKKDSTGICFIGERHFSDFLKNYLPVKKGLIKDWKTKQTISEHDGVWFYTIGQRSGLNLGGLKQRHFVVAKDIETNELFVSCDKEELLKTTILLDQFNWLYTPKQLPSQVLVRIRHAQKPEIAKLKLLSDNKLEITFKNPVISVASGQFGVLYTLDQICLGAGLI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRY_BUBBU
Sequence: MFRVLNDDVYSPAVVQQQNILAFRKDSSSCTDSHSANDQCERGENVRESSQDHIKRPMNAFILWSRERRRKLALENPKMKNSEISKQLGYEWKRLTDAEKRPFFEEAQRLLSIHRDKYPGYKYRPRRKAKRLQKSLPADSSILCNPMHVETLHPFTYRDGCAKTTYSQMESQLSRSQSVIITNSLLQKEHHSSWTSLGHNRVTLATRISEDFPFNKSLEPGLSCAYFQY
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: PUR7_METTH
Sequence: MDVKIDGPLYSGKAKDVLLTDDPEIVAVRFRDDITAGDGEKKDTLEMKGYYNSVISAKIFEVLEEAGVPTQYLELREPGCILARKLEMIPIEVITRNIAAGSIVRRFPFTEGQEFVPPLIQMDYKSDEHGDPMLNDDIILALGIATRDELEEIRRITLHINSVLRDFLKSRGLILPDFKLEFGRDSSGRIRLGDEVSPDTCRLWDMETGEPLDKDIFRRGEEGVVGAYRRVARMILDDEDIERWNVEL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RS13_AERS4
Sequence: MARIAGINIPDHKHAVIALTAIYGVGRTRSKAICAAAGIAENVKIKDLDEAQIESLREQVGKFTVEGDLRRQISMNIKRLMDLGCYRGLRHRRSLPVRGQRTKTNARTRKGPRKAIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PURT_CUPNH
Sequence: MTTLGTPLSPSATKVMLLGSGELGKEVLIALQRLGVETIAVDRYDNAPGQQVAHHARTIAMSDPDQLKALIEAEKPHLVVPEIEAIATPMLETLEAAGTVRVIPTARAARLTMDREGIRRLAAESLGLPTSPYKFCDSLDELQAAIDGGIGYPCVVKPVMSSSGKGQSKIDGPEGVKAAWDYAMAGGRVSHGRVIVEGFIDFDYEITLLTVRAMGASGQVETQFCAPIGHVQVSGDYVESWQPQPMHPAALETAQRIAQAVTADLGGMGLFGVELFVKGEQVWFSEVSPRPHDTGMVTMATQWQNEFELHARAILGLPVDTTLRSPGASAVIYGGVDAQGVVFDGVDQALSVPQTEVRLFGKPESFVKRRMGVALAYADDVDTARTRAKEAASRVRPRAVG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: NQRA_NEIG1
Sequence: MIKIKKGLNLPIAGRPEQVIYDGPAITEVALLGEEYVGMRPSMKIKEGEAVKKGQVLFEDKKNPGVVFTAPASGKIAAIHRGEKRVLQSVVIAVEGNDEIEFERYVPEALAKLSSEKVRRNLIQSGLWTALRTRPFSKIPAVDAEPFAIFVNAMDTNPLAADPTVIIKEAAEDFKRGLLVLSRLTERKIHVCKAAGADVPSENAANIETHEFGGPHPAGLSGTHIHFIEPVGANKTVWTINYQDVIAIGRLFVTGRLNTERVVALGGLQVNKPRLLRTVLGAKVSQLTAGELVDADNRVISGSVLNGAIAQGAHDYLGRYHNQISVIEEGRSKELFGWVAPQPDKYSITRTTLGHFLKNKLFKFTTAVNGGDRAMVPIGTYERVMPLDILPTLLLRDLIVGDTDSAQALGCLELDEEDLALCSFVCPGKYEYGPLLRKVLETIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: CRGA_STRAW
Sequence: MPKSRIRKKADYTPPPSKQATNIKLGSRGWVAPVMLAMFLIGLAWIVVFYVTDGSLPIDALDNWNIVVGFGFIAAGFGVSTQWK
What is the function of this protein?
Involved in cell division.  Coordinates growth and cell division.  Required for the formation of the sporulation septa.
What are the official names of this protein?
Cell division protein CrgA.
What is the protein family that this protein belongs to?
Belongs to the CrgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ILVC_MOOTA
Sequence: MAVVYYDQDADLNVLKGKKIAVMGYGSQGHSQAQNLKDSGLDVVVGLRPESKSRAAAQAAGLEVKTVAEAAAEADIIQILLPDETQARVYREEIAPYLTGGKVLMFSHGFNIHFNQIVPPADVDVIMVAPKGPGHLVRRTYVEGQGVPALIAIYQDASGKAKEIGLAYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGTTALVKAGFETLVEAGYQPEIAYFECLHELKLIVDLMYEGGIKYMRYSISDTAEYGDVTRGPRLIDDHVKSTMKSILKEIQDGVFAREWILENQAGRPSFNAFRKKEREHLIEQVGDQLREMMSWLKK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YJFN_ECO57
Sequence: MKQLLASPSLQLVTYPASATAQSAEFASADCVTGLNEIGQISVSNISGDPQDVERIVALKADEQGASWYRIITMYEDQQPDNWRVQAILYA
What are the official names of this protein?
Uncharacterized protein YjfN.
What is the protein family that this protein belongs to?
Belongs to the BhsA/McbA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RFNG_RAT
Sequence: MSRVRRVLCRACLALAAVLAVLLLLPLPLPLPLPLPRAPAPDPGRVPTGSLTLEVSRLQPDDVFIAVKTTRKNHGPRLRLLLRTWISRAPRQTFIFTDGDDPELQLLAGSQMINTNCSAVRTRQALCCKMSVEYDKFIESGRKWFCHVDDDNYVNPKSLLHLLSTFSSNQDIYLGRPSLDHPIEATERVQGGGTSNTVKFWFATGGAGFCLSRGLALKMSPWASLGSFMSTAERVRLPDDCTVGYIVEGLLGARLLHSPLFHSHLENLQKLPSGAVLQQVTLSYGGPENPHNVVNVAGSFSIRQDPTRFQSVHCLLYPDTHWCPMKNRGKEAFQ
What is the function of this protein?
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules.  Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in enhancement of NOTCH1 activation by DLL1 and JAG1 (By similarity).  Inhibits Notch signaling in postmitotic neurons of the brain.  It may play a role in adult brain and in neurogenesis (PubMed:11165380).  It may play a role in limb development (By similarity).
What are the official names of this protein?
Beta-1,3-N-acetylglucosaminyltransferase radical fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: COXX_BURM7
Sequence: MDTTLSHTPGSRLSQYLALTKPRVTQLAVFCAVIGMFLATPGMVPWKVLLGGTIGIGLLAGSAFAINCLVEQKIDAMMRRTAWRPSARGEITTLQILAFSTVLGGLGAWTLYTFTNPLTIWLTIATFVGYAVIYTLLLKPMTPQNIVIGGASGAMPPALGWAAVTGAVPGDAWILVLIIFVWTPPHFWVLALYRRKDYENAGLPMLPVTHGEQFTRLHILLYTVILFAVTMMPFISGMSGAVYLTSAVLLGALFLAYAWKIYRDYSDALARRAFRYSIVYLSLLFAALLVDHYARPVIGM
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAA_FRATN
Sequence: MTDIHNHKILILDFGSQYTQLIARRVREVGVFCEIFPHDVAADFIKNYQAKGIILSGGPESVYDSDVKAPEIVFKLGIPVLGICYGMQTMVMQHGGEVKGADQSEFGKAIINILNSTNNIFSNMEHEQLVWMSHSDKVTQTGEHFEIIASSTNAPVAAVAHKSKPFFGVQFHPETTHTENGKQIIENFVVNICGCDTLWNIENIIENDIKEIKQKVGTDKVILGLSGGVDSSVVAAILHQAIGDQLTCIFVDTGLLRLNEGNQVMQVFAEHMDINVIRINAKNRFLDALRGICDPEQKRKIIGKLFVDIFDEEAAKIENAKWLAQGTIYSDVIESAGNNQSKAHVIKSHHNVGGLPKEMKLKLLEPLRELFKDEVRKLGLGLGLPYNMLYRHPFPGPGLGVRILGEIKKEYVETLQKADAIFTEELYKHNLYHDVSQAFGVFLPVKSVGVVGDQRRYEYVIALRAVVSIDFMTATWANLPYDFLSLVSNRIVNEVKQVSRVVYDVTGKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: TANC2_MOUSE
Sequence: MFRNSLKMLLTGGKSSRKNRSSDGGSEEPPDRRQSSVDSRQSRSGQGGISTESDCAFEPDYAVPPLPVSEGDVEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPSDQYSMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCSTLPPVSTNAAAKDCSYGAVTSPTSTLESRDSGIIATLTNYSENMERTKYVGEGSKELGSGGNLKPWQSQKSSMDSCLYRVDENMAASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSLSGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNQGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQAPSAHSSITSGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLTAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGNFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGSIEGTLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLKEAIKLCPNNREIQRLLMRVEEECRQMQQQQQQQPPPPPQQPPQELPEEETEPEPQHEDIYSVQDIFEEEYLEQDVENVSIGLQTEARPSQGLPVIQSPPSSPAHRDSAYISSSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPALSPTHQNSHYRPSPPHTSPAHQGASYRFSPPPVGGQSKEYPSPPPSPLRRGPQYRASPPAESMSVYRSQSGSPVRYQQETNVSQLPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYGQVAHSMASKYQSSQGDMGVSQSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLTKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPTFRPSSSIQQMEIPLKPAYDRSCDELSPVSPTQGGYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDDYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV
What is the function of this protein?
Scaffolding protein in the dendritic spines which acts as immobile postsynaptic posts able to recruit KIF1A-driven dense core vesicles to dendritic spines.
What are the official names of this protein?
Protein TANC2, Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the TANC family.
What are the subcellular locations of this protein?
Cell projection, dendritic spine.
Protein: CYB_SINMA
Sequence: MSNQHTLLISNLLPVGSNISTWWNFGSMLLICLTLQIMTGFFLAIHYTANINLAFSSVVHITRDVPYGWIMQNLHTIGASMFFICIYTHIARGLYYGLYLNKSVWLSGTTLLITLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTITTWLWGGFSINDPTLTRFFALHFIIPFAIISLSSIHIILLHNKGSNNPLGTNSDIDKIPFHPYHSYKDTLTSTFMLITLFIILSFTPDLFNDPENFSKANPLITPQHIKPEWYFLFAYGILRSIPNKLGGTLALLMSVIILTTMPFTHTSYVRSMTFRPLAQTMFWMLIATFITITWTASKPVEPPFIIISQTTSIFYFSFFIMNPLLGWTENKIMMNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NDK_ECO8A
Sequence: MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S39A9_RAT
Sequence: MDDFLSISLLSLAMLVGCYVAGIIPLAVNFSEERLKLVTVLGAGLLCGTALAVIVPEGVHALYEEVLEGKHHQASEAKQNVIASDKAAEISVVHEHEHSHDHTQLHAYIGVSLVLGFVFMLLVDQIGSSHVHSTDDPESARPSSSKITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPAMSMLTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEDTSTNQSGSSLSPRPLPSGKN
What is the function of this protein?
Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis.  Participates in the zinc ions efflux out of the secretory compartments.  Regulates intracellular zinc level, resulting in the enhancement of AKT1 and MAPK3/MAPK1 (Erk1/2) phosphorylation in response to the BCR activation (By similarity).  Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1 (PubMed:27164415, PubMed:35625396).  This pathway contributes to CLDN1 and CLDN5 expression and tight junction formation between adjacent Sertoli cells (PubMed:27164415, PubMed:35625396).  Mediates androgen-induced vascular endothelial cell proliferation through activation of an inhibitory G protein leading to the AKT1 and MAPK3/MAPK1 (Erk1/2) activation which in turn modulate inhibition (phosphorylation) of GSK3B and CCND1 transcription.  Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process (By similarity).
What are the official names of this protein?
Zinc transporter ZIP9, Solute carrier family 39 member 9, Zrt- and Irt-like protein 9, ZIP-9.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CYB_CHISV
Sequence: MPHQQILMLFGLLPVATNISTWWNFGSMLLACSTLQVLTGFFLAVHYTANINMAFSSIIHITRDVPYGWLMQNLHAIGASMFFICIYIHIARGLYYGSYLNKETWLSGTTLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGSTMTTWLWGGFAINDPTLTRFFALHFILPFGIISLSSLHILLLHEEGSSNPLGTNSDIDKIPFHPYQTYKDLLMLAMLTTLLLMIVSFFPDIFNDPDNFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALTMSIMILLTVPFTHTSKLRSMMFRPLMQLMFWTFAATFLVISWSSTKPVEPPFTTISQAAALMYFLFFISKPLMGLMENKIMKT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RUVA_SINFN
Sequence: MIGKLKGTIDEIGEDFVVLDVHGVGYVAYCSARTLAKLGSAGEAAVLFIETYVREDQLRLFGFLSALEREWFRLLQTVQGVGSKVALALLTTLTPGELANAIALQDKTSVARAPGVGPKVAVRIVTELKNKAPAFAGEMSASIGLKQELGEGVAAAPVSDAVSALTNLGYSRDQAANAVAAALKNGGEGGDSAKLIRLGLKELAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RSSA1_SCHJY
Sequence: MAQAGRPSILNATDDDIKQLLAASCHIGSKNLDVRMENYVWKRRSDGVHIINIGKTWEKIVLAARVIATIENPADVCVVSSRPYGHRAVLKFAAHTGATAIAGRFTPGNFTNYITRTYREPRLIIATDPRADAQAIKEASYVNIPVISLCDTDSPLAHVDVAIPTNNKGYKSIGLVWWLLAREVLRLRGTISRTSPWDVMVDMYFYRDPEEIEREEEAKAAAEAEAEAAATAEAAAEFEVTDSAAGTVDPSVLAAATAGQVGESSWEEAGDWNTTGAAQTSDWAATAEAQ
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0-A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPC_DICDI
Sequence: MLTNNEIYQEVQKFAKGYDLNQDGVLTSQEIYYSLLKKMNGNSYEASKATGVLCSTIDINKDGKFSYHEIAKYCADNAKKLIEQNADIAALADVEAFLLRFDKDKDRKLNKTEFVEYFKGGTDTPYSDRDYVLKIIDLDKDGCVSANELQEWFKKKRIDYASRPHC
What is the function of this protein?
Plays a role during cell aggregation and slug migration.
What are the official names of this protein?
Calcium-binding protein C, Calcium-binding protein 3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS16_DECAR
Sequence: MVVIRLARGGAKKRPFYNMVVTDSRNRRDGRFVERIGFYNPVASGNAEALRVSVDRLAYWQSNGAQLSPTVARLVKQHAAQQAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: YCIB_BRUA4
Sequence: MEHPVFERDPSQKSEAERREVPPLLKLALELGPLLVFFFANARGEMLIERFPVLASIGAPIFLATALFMGATVIALAISWTMTRTLPIMPLVSGIVVLVFGALTLWLHNDTFIKMKPTIVNTLFGAILLGGLFFGKSLLGYVFDSAFRLDAEGWRKLTLRWGLFFIFLAVVNEVVWRNFSTDAWVSFKVWGIMPITIVFTLLQMPLIQKHSLTEDNKTAS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPF_PEDPA
Sequence: MFSHIIVGAAHGSTLYVGDMLFYAILFIVLMALIAKFAWGPVNAMLKERADRISNDIDSAEQSRIEAEKLAKQRKEALDNSHAEATSIINNAKDSGAKERELIIGNAQNEAKSLKDKAKQDIEQERADALKSAQDDIASLSIEIASKVIKKELDENSQKDLIDSYIEGLGDSK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RECR_ALKCK
Sequence: MQYPRPIAKLIEGFTRLPGIGPKTASRLAFHVLDMKEDDVLEFAKALVHAKRDLTYCSQCHNITDTDPCQICEDKHRDRTTICVVQESRDLIAMEKMREYTGLYHVLHGAISPMDGIGPEDIKIAELIKRLQDDESVKEVIVATNPTIEGEATAMYISRLIKPTGIKVTRLAHGLPVGGDLEYADEVTLSKAIEGRREL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RPIA_BURM9
Sequence: MTQDELKRLVGEAAARYVTENVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVATTERLKSHGIKVFDLNEIESLQVYVDGADEIDGSGAMIKGGGGALTREKIVASVAETFVCIADASKRVAVLGQFPLPVEVVPMARTAIGRRLAALGGVPVLRVKQDGAPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTERGVETLRYAAH
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: ARAB_SHIB3
Sequence: MAIAIGLDFGSDSVRALAVDCASGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAEKPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKAQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.