PharMolix/UniProtQA huggingface dataset:
Protein: GPA1_YEAST
Sequence: MGCTVSTQTIGDESDPFLQNKRANDVIEQSLQLEKQRDKNEIKLLLLGAGESGKSTVLKQLKLLHQGGFSHQERLQYAQVIWADAIQSMKILIIQARKLGIQLDCDDPINNKDLFACKRILLKAKALDYINASVAGGSDFLNDYVLKYSERYETRRRVQSTGRAKAAFDEDGNISNVKSDTDRDAETVTQNEDADRNNSSRINLQDICKDLNQEGDDQMFVRKTSREIQGQNRRNLIHEDIAKAIKQLWNNDKGIKQCFARSNEFQLEGSAAYYFDNIEKFASPNYVCTDEDILKGRIKTTGITETEFNIGSSKFKVLDAGGQRSERKKWIHCFEGITAVLFVLAMSEYDQMLFEDERVNRMHESIMLFDTLLNSKWFKDTPFILFLNKIDLFEEKVKSMPIRKYFPDYQGRVGDAEAGLKYFEKIFLSLNKTNKPIYVKRTCATDTQTMKFVLSAVTDLIIQQNLKKIGII
What is the function of this protein?
Alpha subunit of the heterotrimeric guanine nucleotide-binding protein (G protein) that mediates mating pheromone signal transduction.  Binding of alpha-factor or a-factor to its cognate transmembrane receptor STE2 and STE3, respectively, allows the receptor to serve as a guanine nucleotide exchange factor (GEF) on GPA1.  The exchange of GDP for GTP on the G protein alpha subunit alters its interaction with the G protein beta subunit STE4, leading to dissociation of the G protein beta-gamma dimer STE4-STE18.  The dissociated subunits activate downstream effectors to activate the mating response pathway and induce changes necessary to produce mating-competent cells.  STE4-STE18 activate the downstream pheromone signaling MAP kinase cascade leading to expression of mating-specific genes, inducing cell cycle arrest in G1, promoting polarized cell growth to form mating projections (shmoos), and establishing the changes in plasma membrane, cell wall and nuclear envelope to permit cell-cell fusion (plasmogamy) and fusion of the two haploid nuclei (karyogamy).  GPA1 transmits a signal that requires direct binding to the effector enzyme PI3K located at the endosome, promoting increased PI3 production.  The intrinsic GTPase activity of GPA1 determines the duration of signaling, and is dramatically accelerated by the RGS protein SST2.  In unstimulated cells, GDP-bound GPA1 sequesters the G protein beta-gamma subunit STE4-STE18, preventing it from activating the downstream effectors.  Also down-regulates the signal by inhibiting the pheromone-induced accumulation of FUS3 in the nucleus.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-1 subunit, GP1-alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Endosome membrane; Lipid-anchor; Cytoplasmic side. Note=Localizes predominantly to the plasma membrane in its inactive, GDP-bound form, and is directed to endosomes once in its active, GTP-bound form. Concentrates at the tip of the mating projections.
Protein: RBL_CYAM1
Sequence: MAQSVQERTRLKNKRYESGVIPYAKMGYWNPNYVVKDSDMLALFRVTPQPGVDPIEAAAAVAGESSTATWTVVWTDLLTACDVYRAKAYRVDPVPTAPDQYFVYIAYDIDLFEEGSIANLTASIIGNVFGFKAVKALRLEDMRIPFSYLKTFQGPATGVIVERERLNKFGRPLLGCTVKPKLGLSGKNYGRVVYEGLKGGLDFLKDDENINSQPFMRWRDRYLYVMEGVNRAAAASGEVKGSYLNVTAATMEECYKRAEFAKEVGSVIIMIDLVIGYTAIQTMAIWARENNMILHLHRAGNSTYSRQKNHGINFRVISKWMRMAGVDHIHAGTVVGKLEGDPIIIKGFYNTLLLPKLEVNLPQGLFFEMDWASLRKTLPVASGGIHAGQMHQLLHYLGEDVVLQFGGGTIGHPDGIQAGATANRVALEAMVLARNEGRDYFNEGPQILRDAAKNCGPLQTALDLWKDIAFNYTSTDTSDFVETPTANV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TKN1_UPEIN
Sequence: QADPNAFYGLM
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Uperin-1.1.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQGF_ECOSE
Sequence: MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNIIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVDVKLHDERLSTVEARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAC_KLEAE
Sequence: MNLRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGEMDQQLLIRTKRGVTPTEAGKILYTHARTILRQCEQAQLAVNNVGQTLRGQVSIGLAPGTAASAITMPLLQTVRNELPEVMVYLQESSGTALNDKLLAGQLDMAVLYERSPVAGIVSQPLLKEDLYLVGTRDCPGQSVDLTAVAEMNLFLPRDYSAVRARVTEAFTLRRLSAKIIGEIESITTLTAAIASGMGATVLPESAARSLCGAANGWMARISTPSMSLSLSLNMSARGSLSPQAQAVKEILLSLVSRPSLENRELQLVS
What is the function of this protein?
Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation.  Negative regulator of its own expression.
What are the official names of this protein?
Nitrogen assimilation regulatory protein nac, Nitrogen assimilation control protein.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: HIS4_METCA
Sequence: MLLIPAIDLKDGKCVRLRQGRMEDDTVFSDDPVAVAGRWVAAGARRLHLVDLDGAFAGKPRNAETIHAIREACPDVEIQVGGGIRDEETIQGYLNAGVDFVIIGTKAVSAPHFVSDVTAEFPNHIIIGLDARDGKVAIDGWSKLSHHDVIDLAQKFEADGVEAIIYTDISRDGMMGGVNIEATSRLARAIHIPVIASGGITTIDDIKALGEIVGDGVIGAITGRAIYEGTLDFAEGLKLAETF
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_CHRVO
Sequence: MDRYDFPDAQGHFGPYGGVYVAETLMVALDQLKEEYARVKADPTFWQEFHHELKHYVGRPSPVYHAKRWSEQLGGAQIWFKREDLNHTGAHKINNAIGQALLARRMGKKRVIAETGAGQHGVATATVAARYGMECVVYMGAEDVKRQSPNVFRMKLLGATVVPVESGSKTLKDALNEAMRDWVTNVDSTFYILGTAAGPHPYPMLVRDFVSVIGAESKIQMPEAIGRQPDVVVACVGGGSNAIGMFHPYIEVPGVRMVGVEAGGHGVASGKHAAPISSGAPVGVLHGSKSYLMQDADGQIVETHSVSAGLDYPGVGPEHCHLKDIGRAEYVSIDDDEALRAFHDCCHLEGIIPALESSHALAWAAKVAPSMGKDQVILVNLSGRGDKDINTVAGLAGITL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SIA7C_RAT
Sequence: MACILKRKPALAVSFIALCILLLAMRLANDVTFPLLLNCFGQPKTKWIPLSYTLRQPLQTHYGYINVRTQEPLQLNCNHCAVVSNSGQMVGQKVGEEIDRASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPLLLKNPDYFFKEASTTIYVIWGPFRNMRKDGNGIVYNMLKKTVDAYPDAQIYVTTEQRMTYCDGVFKDETGKDRVQSGSYLSTGWFTFILAMDACYSIHVYGMINETYCTTEGYRKVPYHYYEQGKDECNEYLLHEHAPYGGHRFITEKKVFAKWAKKHRIVFTHPNWTVS
What is the function of this protein?
Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the GalNAc residue on the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc sequence of glycoproteins and glycolipids forming an alpha-2,6-linkage.  Produces branched type disialyl structures by transfer of a sialyl group onto a GalNAc residue inside the backbone core chains.  ST6GalNAcIII prefers glycolipids to glycoproteins, predominantly catalyzing the biosynthesis of ganglioside GD1alpha from GM1b (PubMed:8631773).  GD1alpha is a critical molecule in the communication and interaction between neuronal cells and their supportive cells, particularly in brain tissues, and functions as an adhesion molecule in the process of metastasis (By similarity).  Sialylation of glycoproteins or glycosphingolipids is very important in tumor development, neuronal development, nerve repair, immunological processes and regulation of hormone sensitivity (By similarity).
What are the official names of this protein?
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3, GalNAc alpha-2,6-sialyltransferase III, ST6GalNAc III, ST6GalNAcIII, STY, Sialyltransferase 7C, SIAT7-C.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: POLSF_CHIKS
Sequence: MEFIPTQTFYNRRYQPRPWTPRPTIQVIRPRPRPQRQAGQLAQLISAVNKLTMRAVPQQKPRKNRKNKKQKQKQQAPQNNTNQKKQPPKKKPAQKKKKPGRRERMCMKIENDCIFEVKHEGKVTGYACLVGDKVMKPAHVKGTIDNADLAKLAFKRSSKYDLECAQIPVHMKSDASKFTHEKPEGYYNWHHGAVQYSGGRFTIPTGAGKPGDSGRPIFDNKGRVVAIVLGGANEGARTALSVVTWNKDIVTKITPEGAEEWSLAIPVMCLLANTTFPCSQPPCIPCCYEKEPEETLRMLEDNVMRPGYYQLLQASLTCSPHRQRRSTKDNFNVYKATRPYLAHCPDCGEGHSCHSPVALERIRNEATDGTLKIQVSLQIGIGTDDSHDWTKLRYMDNHIPADAGRAGLFVRTSAPCTITGTMGHFILARCPKGETLTVGFTDSRKISHSCTHPFHHDPPVIGREKFHSRPQHGKELPCSTYVQSNAATAEEIEVHMPPDTPDRTLLSQQSGNVKITVNSQTVRYKCNCGGSNEGLITTDKVINNCKVDQCHAAVTNHKKWQYNSPLVPRNAELGDRKGKIHIPFPLANVTCMVPKARNPTVTYGKNQVIMLLYPDHPTLLSYRSMGEEPNYQEEWVTHKKEVVLTVPTEGLEVTWGNNEPYKYWPQLSANGTAHGHPHEIILYYYELYPTMTVVVVSVASFILLSMVGMAVGMCMCARRRCITPYELTPGATVPFLLSLICCIRTAKAATYQEAAVYLWNEQQPLFWLQALIPLAALIVLCNCLRLLPCCCKTLAFLSRNEHRCPHCERVRTRNSDPEHGGSTV
What is the function of this protein?
Plays a role in viral assembly and release.
What are the official names of this protein?
Frameshifted structural polyprotein, p130.
What is the protein family that this protein belongs to?
Belongs to the alphavirus frameshifted structural polyprotein family.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm. Host cell membrane. Host nucleus. Note=Shuttles between the cytoplasm and the nucleus. SUBCELLULAR LOCATION: [Spike glycoprotein E2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: ATPE_GEOSE
Sequence: MKTIHVSVVTPDGPVYEDDVEMVSVKAKSGELGILPGHIPLVAPLEISAARLKKGGKTQYIAFSGGFLEVRPDNVTILAQAAERAEDIDVLRAKARKSGRTPLQSQQDDIDFKRAELALKRAMNRLSVAEMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSTB1_MYCTU
Sequence: MAKRLDLTDVNIYYGSFHAVADVSLAILPRSVTAFIGPSGCGKTTVLRTLNRMHEVIPGARVEGAVLLDDQDIYAPGIDPVGVRRAIGMVFQRPNPFPAMSIRNNVVAGLKLQGVRNRKVLDDTAESSLRGANLWDEVKDRLDKPGGGLSGGQQQRLCIARAIAVQPDVLLMDEPCSSLDPISTMAIEDLISELKQQYTIVIVTHNMQQAARVSDQTAFFNLEAVGKPGRLVEIASTEKIFSNPNQKATEDYISGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import (Probable).  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YODE_ECOLI
Sequence: MGNDAFKLSSADRGDITINNESGHLIVNTAILSGDIVTLRGGEIRLVL
What are the official names of this protein?
Protein YodE.
Protein: SYC_SALTI
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHQDFDALNILRPDSEPRATHHIQEIIELTRTLIEKGHAYVADNGDVMFDVPTDPTYGQLSRQDLEQLQAGARVDVVDVKRNPMDFVLWKMSKEGEPSWPSPWGEGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGEYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLYTALRGTDKSAAPAGGEAFEARFVEAMNDDFNTPEAYSVLFDMAREVNRLKGEDMTAANAMASHLRKISGVLGLLEQEPDVFLQSGAQADDGEVAEIEALIQQRLDARKAKDWAAADAARDRLTEMGIILEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_JANSC
Sequence: MFQGSMPALVTPMTNGAVDFEVLKRLVDWHVEEGSNGLVPVGTTGESPTLTHEEHEQVIETVVKAAGGRVPVIAGAGSNNTAEAMRHVQHAKDVGADATLVVTPYYNKPTQRGLIAHYEALAEVGIPIFIYNIPGRSVVDMTPETMGELAKHPMIIGVKDATADMARVSRQRETCGTDFVQMSAEDASALGFNAHGGVGCISVTANVAPKLCAEFQAAMGAGDYTEALAYQDRLMPLHNAIFTEPGLCGVKYAMSVLGLCSDEVRLPLVGVDESTKAAIEAALRHAGLLS
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_CORK4
Sequence: MKHLLSMADLSADEITGLLDEAQNFKEALEGRELKKLPTLRGRTIFTVFYENSTRTRSSFETAGKWMSADVINISASSSSVKKGESLQDTGLTLTAIGADALIIRHPSSGAAQQLAHWVAPNGDGPSVINAGDGAHQHPTQALLDALTLRQRLGGINGRKIVIVGDILHSRVARSNAELLTKLGAEVVYVAPPTLLPYGVETWPVRISYDMDSELADADAIMMLRVQAERMAGGFFPSHREYATLYGMSTAREAKMKDKAIIMHPGPMLRGMEINYSVADAPRTAVLQQVNNGVHVRMAVLFSLIIGTHGQSHTTKES
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL15_LAWIP
Sequence: MNLTTLYPFLEERKLRKRVGRGSASGLGCTSGKGNKGQNARSGGGVRPGFEGGQMPLQRRLPKHGFKNAFFKVEYAIFNLDWLTTFFKGKNEILLEDIYSHKLCSVGTPVKILGSGSISNIVTIEAHKFSRSALKKLHEVGGQAKIIEK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ACT_THELA
Sequence: MEEEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIGMGQKDSYVGDEAQSKRGVLSLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPINPKSNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGFALTHAISRIDIAGRDLTDYLMKILAERGYSFTTTAEREIVRDIKEKLCYVAFDFEQELQTAAQSSTLEKSYELPDGQVITIGNERFRAPEALFNPAVLGHESGGIHETTFNSIIKCDVDVRKDLYGNIVMSGGTTMYPGIADRMQKELTALAPSSMKIKIIAPPERKYSVWIGGSILASLSTFQQMWVSKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL28_YERPY
Sequence: MSRVCQVTGKRPMSGNNRSHAMNATKRRFLPNLHSHRFWVEGEKRFVTLRVSAKGMRVIDKKGIETVLAEIRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: SPIST_SANSP
Sequence: MENQKMPISSVSNLKDLNMISRPVANFPPSIWGDRFINYACEDENEQAQKERQVEELKEQVRRELATAIDKPLQQLNIIDATQRLGIAYHFENEIEESLKHIYLHTYVENTCFEGSDDLYSVALWFRLLRQDDYRVSCDVFKKFRDSEGNFKNSLMEDAKGLLELYEATHLSVNGEEMLDDALEFTKTHLELVVSHLNYPLAEQVRHALYQPQHKGLPRLEAVYFFRIYEAYDSHNEALLKLAKLDFNLLQSLHMKELSHMAKWWKSLDFATKFPFARDRLVEGYFWILGVYFEPQYSLARKIIIKVFTMISTIDDIYDAYGTLDELKLFTKAIQRWDIGSLDQLPEYMKPCYKSVLDVYNEIEEEMDNQGSLFRMHYAKEEMKKIVEGYMDEAKWCHEKYVPTFQEYMSVALVTAGYTFLTTISYLGMGEIASKEAFDWLFSRPPIIEASESVCRLMDDMRSHEFEQERGHVASGIECYMKQYGVTEEEAHDKFHKRLVKAWKDINEGCLRPYPMPKPLLMRILSLTRVIDVIYKNEDWYTHVKKPMKDKIASLLIDPMIV
What is the function of this protein?
Sesquiterpene synthase.
What are the official names of this protein?
Probable sesquiterpene synthase, SspiSTPS.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: SYS_ENCCU
Sequence: MIDINLIRDPKTREKVVESEKKRFRDGLAVGKAYELDRKRIEMNFRLDQINTRINQLNREIKSGYRQGKNKEDGDLSEKVAEIKGLSDEAKGLRDDVKAVEDELNKVMKGIGNIISPSVVVSNDEKDNPIVRSYRSSRNMQKNPRPFCVLMKDFTHSVAGAKVMGHRGYYLSGKMARLAQALTRYAIDFLENKGYTYIQTPVMLRRDVMRKTSQLSDFDDQLYKVEDDLYLIATSEQSLAALYMDERMVPQEVPKKFCGQSLCFRKEAGAHGKDNAGLFRVHQFEKIEQFVICGPEESQKYHEEMIKACEEFYQSLDISYNVVGIVSGELNDAAAIKYDLEAYFPSAEKYRELVSCSNCTDYQSRELEIRYGVVKENNRKIYVHLLNGTMCAVQRALCCIVENYQTGDGIAIPDVLQGYFGGDLIELGP
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
Protein: RS12_HAMD5
Sequence: MPTITQLIRKQRVKKSVKSKAPALAASPQKRGVCKRVYTTTPRKPNSAMRKVCTVVFTNGYECICYIGGEGHNVQEHGVLLVKGGGVKDLPGVKYHIVRGALDCSGVKDRKQARSKYGAARPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: CTAA_BRUAB
Sequence: MAATSAQHIGLQGHGTSRNDRDRRLVRYWLYAVFAVLIAIVMVGGATRMTGSGLSITEWKPIHGVIPPLNHAEWVEEFEKYQQIPQYQQINKGMSLAEFQYIFWWEWAHRLLARFVGFLVAVPLGFFWLTGRLKGGLKYRMLGLLALGGLQGAIGWWMVASGLSELTSVSQYRLAIHLTTACVIITAVFYIARGLVTYSERPAERSIQRFAGWIVFAVLVQIYLGGLVAGLHAGLTYNTWPLMDGAIIPSDLFTQAPWWRNLFENPKTVQFVHRMFAYTVLLLAILHAVQVWKNAPGTTHARRTIVLVGLVFIQAMIGIATLLMSAPLHLGLTHQFFALVVLAFAVAHWRATKGAYAA
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AB36G_ORYSI
Sequence: MDAAGEIQKVASMRLGGSMRGDSGSMWRRGDDVFSRSSREEDDEEALRWAALEKLPTYDRVRRAILPLGGDDGAGDGGGKGVVDVHGLGPRERRALLERLVRVADEDNEKFLLKLKDRVDRVGIDMPTIEVRFEHLEAEAEVRVGNSGLPTVLNSITNTLEEAGNALGILPNRKQTMPVLHDVSGIIKPRRMTLLLGPPGSGKTTLLLALAGRLGKDLKASGKVTYNGHGMEEFVPERTAAYISQHDLHIGEMTVRETLAFSARCQGVGSRFDMLTELSRREKAANIKPDADIDAFMKAAAMGGQEANVNTDYILKILGLEICADTMVGDEMLRGISGGQRKRVTTGEMLVGPARALFMDEISTGLDSSTTFQIVNSLRQTVHILGGTAVISLLQPAPETYNLFDDIILLSDGQIVYQGPREDVLEFFESTGFKCPDRKGVADFLQEVTSKKDQRQYWARHDKPYRFVTVKEFVSAFQSFHTGRAIANELAVPFDKSKSHPAALATTRYGAPGKELLKANIDREILLMKRNSFVYMFRTFQLMVVSLIAMTLFFRTKMKRDSVTSGGIYMGALFFGVLMIMFNGFSELALTVFKLPVFFKQRDLLFYPAWSYTIPSWILKIPITFIEVGGYVFLTYYVIGFDSNVGSFFKQYLLMLAINQMAGSLFRFIGGAARNMIVANVFASFMLLIFMVLGGFILAREQVKKWWIWGYWISPMMYAQNAISVNELMGHSWNKIVNSSASNETLGVQVLKSRGVFPEARWYWIGFGAMIGFTILFNALFTLALTYLRPYGNSRQSVSEEELKEKRANLNGEIVGDVHLSSGSTRRPMGNGTENDSTIVDDDTEVTQRGMVLPFTPLSLSFDNVRYSVDMPQEMKAQGVADDRLELLKGVSGSFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIEGSINISGYPKKQETFARVSGYCEQNDIHSPQVTVYESLLFSAWLRLPEDVDSNTRKMFIEEVMELVELKSLRDALVGLPGVNGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVNTGRTVVCTIHQPSIDIFEAFDELFLMKRGGEEIYAGPLGHHSSELIKYFESIPGVSKIKDGYNPATWMLEVTTIGQEQALGVDFSDIYKKSELYQRNKALIKDLSQPAPDSSDLYFPTQYSQSSLTQCMACLWKQNLSYWRNPPYNAVRFFFTTVIALLFGTIFWDLGGKVTKSQDLFNAMGSMYAAVLFIGVMNCTSVQPVVAVERTVFYRERAAGMYSAFPYAFGQVVIEIPYTLVQATVYGIIVYAMIGFEWTAAKFFWYLFFMVFTLLYFTFYGMMAVGLTPNYHIASIVSSAFYAIWNLFSGFVIPRPRVPIWWRWYCWACPVAWTLYGLVVSQFGDIETPMEDGTPVKVFVENYFGFKHSWLGWVATVVAAFAFLFASLFGFAIMKFNFQKR
What is the function of this protein?
May be a general defense protein.
What are the official names of this protein?
ABC transporter G family member 36, OsABCG36, Pleiotropic drug resistance protein 9, OsPDR9.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYC_EXISA
Sequence: MIQLYNSLTNKKEPFVPIVPGKVSMYVCGPTVYNYIHVGNARPAIAFDTVRRYLTYRGYEVKYVLNFTDVDDKIIRTANELGEDTETLTNRYIEAYLADTGALNVQPADVHPRVTDTMEEIIEFIRQLETEGFAYESEGDVYFRTKKFETYGKLSQQSIEDLRAGSRVDVGEKKEDPLDFVLWKAAKPDEPSWDSPWGKGRPGWHIECSAMAKKHLGTTIDIHAGGHDLKFPHHENEIAQSEACNHAKFANYWLHNGFINIENEKMSKSLGNFLLVHEALKEVDPMVLRFFMLSVHYRHPINYSRELIEQAANGWSRIKEAYQNIEYRLSVTAGLGEASESMERKLESIKASFIESMDDDINTANAVTVLFDLAREANIYAKADHVAKATLEQVLSLFDELTGVLGLTLAEEKELLDAEIDQLIQERNDARAARNFARADEIRDLLKEQNIQLEDTAQGVRWKRL
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_DESVV
Sequence: MLTDPIADMLTRIRNAHLALHKEVSVPRSKMKESLAAILKQEGYIEDVATEEGSIKLTLKYFKGKPVISGLKRVSKPGRRVYVGMHEIPKVQNGLGICILSTSRGVMDGNSAHESKVGGELLCEIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PAND_COREF
Sequence: MLRTILGSKIHRATVTQADLDYVGSITIDADLVNAAGLIEGEKVAVVDITNGARIETYVITGDAGTGSICINGAAAHLINPGDLVIIMSYLQATDAEARAYQPNIVHVDADNRIVALGNDAGEPIPGSSLLSSRSL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTRE_METM5
Sequence: MDPTLISLGALALAGAAATVSGCAEDLESDVGSQSNPNSQVQLGPQMGNIHRYFNKAISGEPVSYGLYVAVAGTIAWALINAGLNAVLAIIVGSGVAAVVHGAYSVSAFLGRTVGQSKKFGQPVYMDVLTSHIGPIVGHGFIAVFTMTLAAYLATTALGNPFPLPLVALIFGITVGAIGSSTGDVHYGAEREYQKYPFGGGIPVANQGDIDIYAEYGVRNGLDSSYFCSRFGGPLTGLCFGLIIFLDGWRSILGNIIGGDLVTKTSIALLVGLLVVAVAAGINRKLEVYARNKYGPYRN
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit E, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E.
What is the protein family that this protein belongs to?
Belongs to the MtrE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.