PharMolix/UniProtQA huggingface dataset:
Protein: CPXR_ECO57
Sequence: MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDSIDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPFNDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALVLNPGRQEASFDGQTLELTGTEFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWFKTLRGRGYLMVSAS
What is the function of this protein?
Member of the two-component regulatory system CpxA/CpxR.  This system combats a variety of extracytoplasmic protein-mediated toxicities.  It performs this function by increasing the synthesis of the periplasmic protease, DegP as well as that of CpxP protein (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein CpxR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_METSB
Sequence: MQVLVRDNNVDQALKALKKKMQREGIFREMKLRGHYEKPSEKRAREKAEAIRRARKLARKKMQREGLLPMKPKPVVGVR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: DNAA_CUPTR
Sequence: MQDFWQAAAAQLERELTPQQFKTWIKPLAPVAFDEETHALRIAAPNRFKLDWVKSQFSGRITALACEYWEAQVSVQFVLDPAASGRAAAYMQPAQPGMGAGGMDRMDHHAAPGTGMGGYPGAQPAQTMGGQAPFAMPGQPAQPGYGEYPTAAAYGLGQPQYGHPTGNPAGMPSAAPVPAGARGQGMGQHPGQHHPQHNAELGEIDVVQMDPAEASARSYRAPQQGQHPHAAMGNGAAQMPGHQPSDTVHERSRLNPILTFDNFVTGKANQLARAAAIQVANNPGKSYNPLYLYGGVGLGKTHLIHSIGNHMLMENPRARIRYIHAEQYVSDVVKAYQRKAFDEFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEALIANRAQVIITSDTYPKEITGIDDRLISRFDSGLTVAIEPPELEMRVAILMKKAAAENVNVPEEVAFFVAKHLRSNVRELEGALRKILAFSNFHGKDITIEVTREALKDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_STRCO
Sequence: MSKRTFQPNNRRRAKTHGFRLRMRTRAGRAILATRRSKGRARLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: GLMM_STRP3
Sequence: MGKYFGTDGVRGEANVELTPELAFQLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: UBP21_ARATH
Sequence: MAEFSDPPPSNLSSSHKLTKPNQTLDESSPTAPIRDLVTNSLSLSSPIRQIQALSPAKPDGSSSSPPDKTLNFNPEENRDVNPDESSSSPSDKTLIAPPAQISPVSNNNHLRITNTSDSYLYRPPRRYIEYESDDDELNKMEPTKPLQLSWWYPRIEPTGVGAGLYNSGNTCFIASVLQCFTHTVPLIDSLRSFMYGNPCNCGNEKFCVMQALRDHIELALRSSGYGINIDRFRDNLTYFSSDFMINHQEDAHEFLQSFLDKLERCCLDPKNQLGSVSSQDLNIVDNVFGGGLMSTLCCCNCNSVSNTFEPSLGWSLEIEDVNTLWKALESFTCVEKLEDQLTCDNCKEKVTKEKQLRFDKLPPVATFHLKRFTNDGVTMEKIFDHIEFPLELDLSPFMSSNHDPEVSTRYHLYAFVEHIGIRATFGHYSSYVRSAPETWHNFDDSKVTRISEERVLSRPAYILFYAREGTPWFSSTFEQLKTVFEATPLHFSPVSVLDNSYESVDNSSKACNDSVGVSIPDVKWPDSCCQEPKEEVFHSAESSNNEDSSAMIDALGSPQSEKPFAETSQQTEPESCPTENKAYIDKSEKPFAETSQPKEPKPFADRASIDAPLLKVQNQDISPKRKAGERATLGGPKLKYQKPNSHQKRQGTFQIQRAHLQTKKQEESRKTKRPLFRSNVAASAPDPKYKNHALSYLNRAQTPRARKLANALSDSPTKKKKSSNMRRSIKL
What is the function of this protein?
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 21, Deubiquitinating enzyme 21, AtUBP21, Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: TON1A_ARATH
Sequence: MDDYTREMMDLKTLVTRTLEKKGVLAKIRAELRASVFEAIEEEDRVIENNEGPPPALLGSCNDRARKLHASPSGRLLSALICEYLDWAQLNHTLIVYQPESNLPKDSWKSELRDFNSNNGFELNRNGDSGPLLLDVLEGFLKFESMTQGMGSSSRRDSETESSSSLESRNPPRRSSASDSLPPQRRPVSASQASDRRAGLSTSGYRKDEFNWRQGNQDTHEEVTRASAALENLQLDRKTRNLTSSWRNVRDGTNEEEGRD
What is the function of this protein?
Involved in the control of the dynamic organization of the cortical cytoskeleton.  May play a role in the organization of microtubule arrays at the centrosome through interaction with centrin 1 (CEN1).
What are the official names of this protein?
Protein TONNEAU 1a, Protein TONNEAU 1.
Protein: S2513_MACFA
Sequence: MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFTSPNDFVTRYLNIFGESQPNPKTVELLSGVADQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNASTGRVTAIDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELTRKIYSTLAGNRKDVEVTKEEFVLAAQKFGQVTPMEVDILFRLADLYEPRGRMTLADIERIAPLEEGTLPFNLAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHARASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFKKILREEGPKALWKGAARVFRSSPQFGVTLLTYELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLPLFKPSVPTSEAIGGGP
What is the function of this protein?
Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (By similarity).  Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton.  Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation (By similarity).
What are the official names of this protein?
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial, Solute carrier family 25 member 13.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DPO3B_STRR6
Sequence: MIHFSINKNLFLQALNITKRAISSKNAIPILSTVKIDVTNEGVTLIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIB_PSEE4
Sequence: MKLLAVRRLLRIQRVVIRYRLDDLLFEQPLLPWWLASLRLLMPWRWLPRKPLALSRGARLRLALQDLGPIFIKFGQLLSTRRDLLPTDIADELMLLQDRVPPFDPQHAVALIEEQLGAKVGEVFSRFDVEPLASASVAQVHAARLKSGEEVVVKVVRPGLKPVIAQDLAWLFLIAKAAERASADARRLHPVEIVGDYEKTIYDELDLLREAANASQLRRNFEGSELMYVPQVYWDLCRPKVLVMERIYGVPVTDMATLADQRTDMKMLAERGVEVFFTQVFRDSFFHADMHPGNIFVSTVKPWSPQYIAIDCGIVGSLTAEDQDYLARNLIAFFKRDYRRVAQLHIDSGWVPAQTKVNEFEAAIRTVCEPIFEKPLKDISFGQVLMRLFQTARRFNMEVQPQLVLLQKTLLNIEGLGRQLYPDLDLWSTAKPFLERWMRERMSPKAVIGNLYNQAEQLPHLADMTRDLLERLSQPHLNDAQLPERRRQGDNWALRLLGAGLLGGGATLAAGAVSLSAPAAWPAWLMLAAGLYLIVRR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: T7358_ILLWI
Sequence: MLKFVVVICLVIMAITFAEKCGDQECGEGTCCLDYSQQHCSRLGKLYDMCSDPNDKTDSGSHIFFCQCETGLRCDKTSWSCQKG
What are the official names of this protein?
U1-hexatoxin-Iw1a, U1-HXTX-Iw1a, Atracotoxin-Hs20f7358, AcTx-Hs20f7358.
What is the protein family that this protein belongs to?
Belongs to the MIT-like AcTx family.
What are the subcellular locations of this protein?
Secreted.
Protein: LACY_KLEOX
Sequence: MKLSELAPRERHNFIYFMLFFFFYYFIMSAYFPFFPVWLAEVNHLTKTETGIVFSCISLFAIIFQPVFGLISDKLGLRKHLLWTITILLILFAPFFIFVFSPLLQMNIMAGALVGGVYLGIVFSSRSGAVEAYIERVSRANRFEYGKVRVSGCVGWALCASITGILFSIDPNITFWIASGFALILGVLLWVSKPESSNSAEVIDALGANRQAFSMRTAAELFRMPRFWGFIIYVVGVASVYDVFDQQFANFFKGFFSSPQRGTEVFGFVTTGGELLNALIMFCAPAIINRIGAKNALLIAGLIMSVRILGSSFATSAVEVIILKMLHMFEIPFLLVGTFKYISSAFKGKLSATLFLIGFNLSKQLSSVVLSAWVGRMYDTVGFHQAYLILGCITLSFTVISLFTLKGSKTLLPATA
What is the function of this protein?
Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Lactose permease, Lactose-proton symport.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Oligosaccharide:H(+) symporter (OHS) (TC 2.A.1.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEXNO_RALSU
Sequence: MTLDVSRQDPRYNTLKHGFNLRWPSTDAQAAGRIALCEKADDVAPALQHIIDTGMRPTVRSGGHCYEDFVSNNPDGAIVDLSLLNAPEVRADGTVRIPAGTQNWNGYLELYKRHNLTLPGGSCYSVGAGGHICGGGYGLLSRLQGLTVDWLSAVDIVTVDRQGRAAPRTVDATRDPELFRACRGAGGGNFGIITAYTFARLPEAPREVALATVAFDWAAMTPERFAELLRLYGEYWETRGKDPDTWGMFSLLKLTHRSAGQIVMLTQFCNPDGTCRDLSVLNDFLARFRACAPVPLKGRPPGYGPAHRQGVGQLLCSKPHTVVRYDWLTATQTVNGSGPNQRGKYKSAYMKRGFTAREAQRIYTHLTRTVPGIDLSQSLLQVDSYGGAVNKTERIADTAVPQRASVMKLQYQTYWTSAADDAGHLRWIGDFYRDVYGTPDVSAPHAGTPYPGDRYEGCYINYPDVDMLAYPFWPQLYYGDGDLYAFLQRVKRRYDPNNIFHHAMSVRP
What is the function of this protein?
Catalyzes the oxidation of a range of monosaccharides in vitro, displaying the highest activity with N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc), with a reduction of O2 to H2O2.  Acts upon the C1 carbon of the GlcNAc or GalNAc molecule, producing the corresponding lactone, which can spontaneously hydrolyze.  Its biological function is unclear, but its main function might be connected to extracellular production of hydrogen peroxide to compete with other organisms through oxidative stress, or support the action of peroxidases and peroxygenases.
What are the official names of this protein?
N-acetyl-D-hexosamine oxidase, HexNAcO.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: Y384_STRPD
Sequence: MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELISRYLEDQASFSFNLGQFDEIWEDYLAH
What are the official names of this protein?
UPF0346 protein MGAS10270_Spy0384.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: FLI1_XENLA
Sequence: MDGTIKEALSVVSDDQSLFDSAYGASSHLSKADMTASANPDYGQPHKINPIPPQQDWINQPMRVNIKREYEHMNGSRESPVDCSINKCSKLIGGSEGNAMTYTYMDEKNGPPPPNMTTNERRVIVPADPALWSQDHVRQWLEWAIKEYGLVEIDCSLFQNIDGKELCKMSKEDFLRSTSIYNTEVLLSHLNYLRDSSSSLGYNTQAHTDQSSRLTAKEDPSYEAVRRSGWGNSMSSPVTKSPPMGGTQNVNKSGDQQRSQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKSIMTKVHGKRYAYKFDFHGIAQALQPHPTDTSMYKYPSEFSYMPSYHSHQQKVNFVPSHPSSMPVTSSGFFGATSPYWNSPSANIYPNPNVPRHPNTHVQSHLGGFY
What are the official names of this protein?
Retroviral integration site protein Fli-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FMP52_ASHGO
Sequence: MNALVVGATGLCGAAILKHAAEATSFNKVYALVRRQIPNSAARVETIVNEQSDSWPESVPAGVDVFFSGLGTTRANAGGLENQYKVDHDLNIAVAKAAKERGCRVCVIVSAIGASVNARLPYNKLKGDIERDLLALEFERTVILRPGVLLGERETHHKGFGNSVAVFLGKLVYRGRFQALLGYPVYGDEVGQVAVALALSDDKSKVRIVESAEILSLVKQENTQ
What are the official names of this protein?
Protein FMP52, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP52 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.
Protein: RL9_BACC1
Sequence: MKVIFLKDVKGKGKKGEVKNVPDGYANNFLLKQGLAAEATNSSMKTLEAQKRKEEKDAAAELENAKQLKETLEKLTVELKAKSGEGGRLFGSITSKQIVDAMQKSHNIKLDKRKFEMDDAIRALGYTNVTVKLHPQVTATVKVHVSEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RS15A_MOUSE
Sequence: MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  Required for proper erythropoiesis (By similarity).
What are the official names of this protein?
40S ribosomal protein S15a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RIMP_LISMH
Sequence: MSKVLEQVEAIVAPITDELQLELVDIVFEKEGPNWFLRIFIDKDGGVDIDECAAVSEKVSEKMDENDPITQNYFLEVSSPGAERPLKKEQDFENAVSKYVHVTSYEPIDGRKMWEGTLVSYDGTTLVITITDKTRKITCEIPKDKVAKARLAIQF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXB7A_XENLA
Sequence: MSSLYYANALFSKYPTATSVFSSGVFPEQTSCAFASNPQRSGYGSSPGGTFPAGSAAHGLYSNGSSLHPQSPAMYPSSYGLDAASFNMHCSPFEQNLSSLMCAGDPTKQNSAKAEQRESELHNEANLRIYPWMRSAGADRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHVLCLTERQIKIWFQNRRMKWKKENKASSPSSNSQEKQETEEEEEE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B7-A, MM3, XlHbox-2 A.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RTNLJ_ARATH
Sequence: MEESVHQSIRFGSVADLIMWKNRRGGFLLLGSTTLLWFLFEKCGYSFFPFVVNTQLLSVVILFLWAKSAILFNRPMPQLPNLEITEEFVFMVADAIRVWINTVLAVAREIYVGRNAKQLFRVSVVLWTVSFVGNFLNFLTILYLGVVLSLLIPFLYERYQDLIDEKLSLTHRVIQTQYRKIDERLLQKIIAKPTNKIKKMQ
What are the official names of this protein?
Reticulon-like protein B10, AtRTNLB10.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SECA2_RHOBA
Sequence: MRRSSDPSANKKKWTKASNWRPRMVRWQRQLARVNALESTLQAEDDQTIRKRSLALRYRAMAGEKLSELLPEAYALCREAGRRSLSMRHYDVQILGGIALFEGHITEMQTGEGKTLTATLPLYLHSLVGKGAHLATVNDYLAKRDAEWMMPLFEMLGVSVGIIQTEDDQGGRRKSYGAAITYGTAKEFGFDFLRDRLLLRAQNRMQTEMLGSGDGGFSNSGDQVVMRGMHFCLVDEADSILIDEARTPLIIGSIEDTVRDQIIETYKWAAENAPLFELDEHFEIDDETKRYELTARGRSKVRALPKSDLVRTMGLVDMYEYIERSIKTHREFLLDRQYVIRPSEKDPNVDEIVIVDEFTGRLAEGRKWRDGIHQSIEAKEGVEISVPTGQAARITVQDLFLRYPHLAGMTGTAATSAGELRKIYRTPVVRVPTNRPPQRIQLPSRVFGTLTSKFEAIAKEVEEIHATGRPVLVGTRSIDKSVLLSKLLDDLGIEHEVLNANNVEREAEIVAEAGGRGKVTVATNMAGRGTDIKLSNDVEQIGGMHVICTELHDAARIDRQLIGRCGRQGDRGSYRQYLSLDDDILKGGYGAIKYEKLKKRGEATSGSVDRLAAMFHKAQRKVERRHFRDRMVLMHHEKERKKMQREIGQDPYLDTPD
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RK12_OLTVI
Sequence: MSTTSEIIEKLKTLTLLEAAELVSQIEETFGVDASAPVGGGMVMAVGDAGGAAEEVAEKTTFDVVVEDIPSDKRVAVLKVIRKLTSLGLAEVKAFTNSLPGTLQEGISKEEAETAKTELEAAGAVVKIA
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LEU3_PICAN
Sequence: MSKNIVLLPGDHVGPEVVAEAVKVLEAVSSAIGVKFNFSKHLIGGASIDAYGVPLSDEALEAAKKADAVLLGAVGGPKWGTGSVRPEQGLLKIRKELNLYANLRPCSFASDALLKLSPLKSEIVKGTDFVVVRELVGGIYFGDRKEDAGDGVASDTESYSVPEVQRITRMAAFLALQSDPPLPLWSLDKANVLASSRLWRKTVEETIKNEFPQLTVQHQLIDSAAMILVKSPTKLNGVIVTNNMFGDIISDEASVIPGSLGLLPSASLASLPDTNKAFGLYEPCHGSAPDLGPGKVNPLATILSAAMMLKLSLDLVDAGRAIEQAVKNVLDAGIMTADLGGSSSTQEVGDAVAQEVAKLLKN
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_VIBC3
Sequence: MKIVEVKHPLVKHKLGLMREGDISTKRFRELATEVASLLTYEATSDFETEKVTIEGWNGPVQVDQIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFNKLATNIEERIAMVVDPMLATGGSMIATIDLLKEKGCNQIKVLVLVAAPEGIAALEKAHPDVELYTAAIDEKLNDKGYIVPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RS3_STAA1
Sequence: MGQKINPIGLRVGIIRDWEAKWYAEKDFASLLHEDLKIRKFIDNELKEASVSHVEIERAANRINIAIHTGKPGMVIGKGGSEIEKLRNKLNALTDKKVHINVIEIKKVDLDARLVAENIARQLENRASFRRVQKQAITRAMKLGAKGIKTQVSGRLGGADIARAEQYSEGTVPLHTLRADIDYAHAEADTTYGKLGVKVWIYRGEVLPTKNTSGGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DPFGH_GIBZE
Sequence: MSPLWVRRLCIRVVDSLYGSFLYLPLAILFLKRSVTGFGTGEWDESQIPKLDGKVAVVTGGNAGIGYYTVKHLASRGAKVYLGARSESRAKAAIKRLLEENPLIPQENVVWLRLDLANQSQVVDAAVELQSKEQRLDILVNNAGIDPYDYIRTADGFEMTMAVKYTNPAAAAQEESDVRVITVSSSGEAYSSPTNQFTSPKDLDDPCASPGWENSCLGQAMRYGTTKLANVLFASELQRRMDEEDANIISLSLNPGTVRTDGAANVMPFMVRPLVRFLFTAPERGADTSLFAATAEEIKENSERWKGRYLDGPGRIKVPSLRARDAVAGRNLWNITEAAVRGTGALDRL
What is the function of this protein?
Short chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of diterpenoid pyrones (PubMed:32286350).  The first step of the pathway is the synthesis of the alpha-pyrone moiety by the polyketide synthase dpfgA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Probable).  The alpha-pyrone is then combined with geranylgeranyl pyrophosphate (GGPP) formed by the GGPP synthase dpfgD through the action of the prenyltransferase dpfgC to yield a linear alpha-pyrone diterpenoid (Probable).  Subsequent steps in the diterpenoid pyrone biosynthetic pathway involve the decalin core formation, which is initiated by the epoxidation of the C10-C11 olefin by the FAD-dependent oxidoreductase dpfgE, and is followed by a cyclization cascade catalyzed by the terpene cyclase dpfgB (Probable).  The short chain dehydrogenase/reductase dpfgG then oxidizes the 8S hydroxy group to a ketone and the short chain dehydrogenase/reductase dpfgH reduces the ketone to the 8R hydroxy group to yield higginsianin B (PubMed:32286350).  Higginsianin B is further methylated by the methyltransferase dpfgI to produce the intermediate named FDDP B (PubMed:32286350).  The cytochrome P450 monooxygenase dfgpJ then catalyzes a three-step oxidation at C-27 to generate a carboxylic acid as well as C-26 hydroxylation (PubMed:32286350).  Finally, methyltransferase dpfgK methylates the carboxylic acid generated by dpfgJ, yielding the final diterpenoid pyrones from the pathway which were named FDDP D and FDDP E (PubMed:32286350).
What are the official names of this protein?
Short chain dehydrogenase/reductase dpfgH, Diterpenoid pyrone biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.