PharMolix/UniProtQA huggingface dataset:
Protein: SYP_PARP8
Sequence: MKASRFFIGTLKEAPADAEIVSHKLMVRAGMIRRVAGGIYNYLPIGLRSIRKVEAIVREEMNRAGAIELLMPAVQPAELWQESGRWEKYGPELLRFKDRKQSDFVIGPTHEEVVTDIARGQIKSYRQLPVNFYQVQTKFRDEIRPRFGVMRGREFIMKDAYSFDKDMDGLRESYRKMYDAYVRIFTRLGLDFRAVAADNGSIGGSGSHEFHVIADTGEDDIAYCPTSDFASNVEAAEALPLIAERAAPKEELRKTSTPGKAKCEAVAEHLNIPLEKTIKSIILATENEGAEPTIWLLMLRGDHDLNEIKVNKLPGLGEFRFATEEEIVEWFGTPPGYLGPLNTKKPIKVIADRTVANMSDFVVGTNEVDFHTTGVNWGRDLPEPVVADIRNVKKDDPSPDGKGVIDICRGIEVGHVFQLGTKYSEAMNATFLDESGKPQPMQMGCYGIGITRILGAAIEQNFDDKGIIWPESIAPFEVVLCPMGYDRSDAVREQADKLHDELTAAGIDVILDDRGERPGVMFADWELIGVPHRLVIGERGLKDGKIEYQGRRDAEATLLPVEAAAQAVIDKIHAALAR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_DICNV
Sequence: MTNIWHTAPVSALSGEITICGDKSMSHRALLLAALAEGQTEIRGFLPCADCLATAQALRALWVDIQREKEIVTIRGVGFLGLQPPKAPLNMQNSGTSMRLLAGILAAQRFESVLCGDESLEKRPMQRIITPLVQMGAKIVSHSNFTAPLHISGRPLTGIDYALPLPSAQLKSCLILAGLLADGTTRLHTCGISRDHTERMLPLFGGALETQKEQIIVTGGQKLHGCVLEIVGDLSAAAFFMVAALIAPRAEVVIRNVGINPTRSAIITLLQKMGGRIELHHQRFWGAEPVADIVVYHSKLRGITVAPEWIANAIDELPIFFIAAACAEGTTFVGNLSELRVKESDRLAAMAQNLQTLGVACDVGADFIHIYGRSDRQFLPARVNSFGDHRIAMSLAVAGVRAAGELLIDDGAVAAVSMPQFRDFAAAIGMNVGEKDAKNCHD
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2C49_ARATH
Sequence: MVAEAEVVFQQSLPAVLEIELFDGVSSAVKSPVSSPKLGFTQSTASVSGSLTTSPVQADIFPEGDCDPSVLDYIPTIRSGSFADIGPKRNMEDEHIRIDDLSSQVGSLFELPKPSAFYAVFDGHGGPEAAAYVRENAIRFFFEDEQFPQTSEVSSVYVEEVETSLRNAFLQADLALAEDCSISDSCGTTALTALICGRLLMVANAGDCRAVLCRKGRAIDMSEDHKPINLLERRRVEESGGFITNDGYLNEVLAVTRALGDWDLKLPHGSQSPLISEPEIKQITLTEDDEFLVIGCDGIWDVLTSQEAVSIVRRGLNRHNDPTRCARELVMEALGRNSFDNLTAVVVCFMTMDRGDKPVVPLEKRRCFSLSPEAFCSLRNLLDG
What are the official names of this protein?
Probable protein phosphatase 2C 49, AtPP2C49.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: MODC_MYCTO
Sequence: MSKLQLRAVVADRRLDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDRVLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGSGRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVLLLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVLVLESGTIAEIGPVADVLTAPRSRFGARIAGVNLVNGTIGPDGSLRTQSGAHWYGTPVQDLPTGHEAIAVFPPTAVAVYPEPPHGSPRNIVGLTVAEVDTRGPTVLVRGHDQPGGAPGLAACITVDAATELRVAPGSRVWFSVKAQEVALHPAPHQHASS
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RSMH_KORVE
Sequence: MDSEDNSAPRGERGIEQFSHVSVLSQEAIDFLAIRRGGTYLDATLGLGGHSYEIAKRLGAQGHLIALDKDTNALEMARRRLEQVPDDLKEDWPQITLLHASFAEMKQHIASKSLDGVLADLGISSMQLQDAGRGFSFQAEGPLDMRMNPHGDLTAEQVVNHTSERELADVIYEFGEERRSRRIARAICRARPIRTTAHLAQVISVAARPMNQAERRIHPATKTFQALRIFVNHELDDLKELLASVPSRLVPRGRLVVISFHSLEDRIVKDSLRDGASAGKYELLTKKPVTATEEEIDRNPRSRSAKLRAAARK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_ECO27
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNATTGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PP377_ARATH
Sequence: MIVFMRIIHVAQTRRLMIRCNRIRQCGFSVKTAALDLESSDSIIPGLDSHAYGAMLRRCIQKNDPISAKAIHCDILKKGSCLDLFATNILLNAYVKAGFDKDALNLFDEMPERNNVSFVTLAQGYACQDPIGLYSRLHREGHELNPHVFTSFLKLFVSLDKAEICPWLHSPIVKLGYDSNAFVGAALINAYSVCGSVDSARTVFEGILCKDIVVWAGIVSCYVENGYFEDSLKLLSCMRMAGFMPNNYTFDTALKASIGLGAFDFAKGVHGQILKTCYVLDPRVGVGLLQLYTQLGDMSDAFKVFNEMPKNDVVPWSFMIARFCQNGFCNEAVDLFIRMREAFVVPNEFTLSSILNGCAIGKCSGLGEQLHGLVVKVGFDLDIYVSNALIDVYAKCEKMDTAVKLFAELSSKNEVSWNTVIVGYENLGEGGKAFSMFREALRNQVSVTEVTFSSALGACASLASMDLGVQVHGLAIKTNNAKKVAVSNSLIDMYAKCGDIKFAQSVFNEMETIDVASWNALISGYSTHGLGRQALRILDIMKDRDCKPNGLTFLGVLSGCSNAGLIDQGQECFESMIRDHGIEPCLEHYTCMVRLLGRSGQLDKAMKLIEGIPYEPSVMIWRAMLSASMNQNNEEFARRSAEEILKINPKDEATYVLVSNMYAGAKQWANVASIRKSMKEMGVKKEPGLSWIEHQGDVHYFSVGLSDHPDMKLINGMLEWLNMKATRAGYVPDRNAVLLDMDDEEKDKRLWVHSERLALAYGLVRMPSSRNRILIMKNLRICSDCHSAMKVISSIVQRDLVIRDMNRFHHFHAGVCSCGDHW
What are the official names of this protein?
Putative pentatricopeptide repeat-containing protein At5g13230, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VE1_HPV2A
Sequence: MEDSEGTDGTEEDGCRAGGWFHVEAIITHGQRQVSSDEDEDETETGEDLDFIDNRVPGDGQEIPLQLYAQQTAQDDEATVQALKRKFVASPLSACSCIENDLSPRLDAISLNRKSEKAKRRLFETEPPDSGYGNTQMVVGTPEEVTGDEESQGGRPVEDQEEERQGGDGEADLTVHTPQSGTDAAGSVLTLLRSSNLKATLLSKFKDLFGVGFYELVRQFKSSKTACADWVVCAYGVYYAVAEGLKKLIQPHTQYAHIQVQTSSWGMVVFMLLRYNCAKNRDSVSKNMSMLLNIPEKHMLIEPPKLRSTPAALYWYKTAMGNGSEVYGETPEWIVRQTLVGHSMEDEQFRLSVMVQYAYDHDIVEESVLAFEYAQLADVDANAAAFLNSNCQAKYVKDAVTMCRHYKRAEREQMSMSQWITFRGNKVSEEGDWKPIVRFLRHQGVEFVSFLAAFKLFLKGVPKKNCIVFYGPADTGKSYFCMSLLQFLGGAVISYANSSSHFWLQPLSDSKIGLLDDATPQCWSYIDIYLRNLLDGHPVSIDRKHKTLLQLKCPPLMITTNTNPLEEDRWKYLRSRLTVFTFKNPFPFASPGEPLYPINNANWKCFFQRSWSRLDLNSPEEQDDNGNTGEPFRCVPGDVARTV
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RL1_PERMH
Sequence: MAKRGKKYLKALELVDKDKLYSIEEAVETLKKMEEVLQRKFDETVELIFRLGVDPKYADQMVRGSVVLPHGLGKELKVLVITQGEKVKEAEEAGADYVGGEDMINKILNENWLDFDVVIATPDMMPKVAKLGRVLGPRGLMPNPKVGTVTQDVKKAVTEAKKGRVEFKVDKTGNLHVPIGKISFDNNKLVENALEVIETVQKLRPSGLKGQYIKNMVMKTTMSPSVKLDVLSILRSLEAKAA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: KARG_ERISI
Sequence: MADAATIAKLDEGFKKLEAATDCKSLLKKYLTKDVFEQLKAKKTKLGATLLDVIQSGVENLDSGVGVYAPDAEAYTLFSPLFDPIIEDYHKGFKQTDKHPNKDFGDVTQFVNVDPDGKFVISTRVRCGRSMEGYPFNPCLTEAQYKEMESKVSSTLSNLEGELKGTYFPLTGMTKEVQQKLIDDHFLFKEGDRFLQAANACRYWPAGRGIYHNDNKTFLVWCNEEDHLRIISMQMGGDLGQVYRRLVSAVNEIEKRVPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGRYSLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMQ
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: PYRF_STRMK
Sequence: MSRAPLPLRDDERLIFALDVPDRAQALEWVDRLGDSVAFYKIGMELLASGEYFQVLDELARRDKRVFVDLKFFDIPATAAAVIKRLSQWPVSYATIHGWHPAMMEACAAANSSDMRLLAVTVLTSMGRPDLAQMGIDREPVDVVVERALAAQAAGIDGVIASGQEAGPIRAATGAGFSIVCPGIRPGGPVGDDQKRTVGVAQAFADGADAIVVGRPIRLATDPQAAARAIQQEIASALAAR
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RNF34_BOVIN
Sequence: MKAGATSMWASCCGLLNEVMGTGAVRGQQSGFAGGTGPFRFTPNSDFSAYPPASAEGPNIVCKACGLSFSVFRKKHVCCDCKKDFCSVCSVLQENLRRCSTCHLLQETAFQRPQLMRLKVKDLRQYLILRNIPIDTCREKEDLVDLVLCHHRLGSEDDLDTSSLNSSRSQTSSFFTHSFFSNYTAPSATASSFQGELMGGDRTLGSGALAQEPSEIASANTEDDEDDDDDDDDDDDDDEENLEDRTPGLTKKRVRASLSDLSSLEDVEGMSVRQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVFKS
What is the function of this protein?
E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins.  Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis.  May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway.  Negatively regulates p53/TP53 through its direct ubiquitination and targeting to proteasomal degradation.  Indirectly, may also negatively regulate p53/TP53 through ubiquitination and degradation of SFN.  Mediates PPARGC1A proteasomal degradation probably through ubiquitination thereby indirectly regulating the metabolism of brown fat cells.  Possibly involved in innate immunity, through 'Lys-48'-linked polyubiquitination of NOD1 and its subsequent proteasomal degradation.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF34, RING finger protein 34, RING-type E3 ubiquitin transferase RNF34.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Endomembrane system; Peripheral membrane protein. Nucleus. Nucleus speckle. Cytoplasm, cytosol.
Protein: LFTR_VIBC1
Sequence: MAIYLTELGDSHSFPSPYDALNDPNGLLAFGGDLNPDRILNGYHQGIFPWYGPGEPILWWSPSPRAVFDPLAFKPSKSLKKFQRKQQYKVTLNNATERVIQLCSSTRSAEETWLNEEMQTSYIELARRGHCHSVEVWHDEKLIGGLYGISVGQLFCGESMFSLKDNASKIALWYLCEHLASNQGQLIDCQVMNPHLASLGAFELERDDFVQKLLSLRDRNINLGTFEPQVLQGAVS
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H90B2_HUMAN
Sequence: MPEEVHLGEKEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNTQEHTLTLVDTGIGMTKADLINNLGTIAKFQDQTEYLEEMQVKEVVEKHSQFLGYPITLYLEKEREKEISDGKAEEEKGEKEEENKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNTEDITQEEYGEFYKSLTNDWKDHLAVRYFSVEEYVSRMKEIQKSIYYITGESKEQVANSAFVEQVWKRDSRVVYMTEPIDGYQLKEFDGKSLVSVTKEGLELPEDGEEKKRMEERKAKFENLCKFMKETLDKKVEMVTVSNRLVSSSCCIVTSTYSWTANMEQIMKA
What is the function of this protein?
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.
What are the official names of this protein?
Putative heat shock protein HSP 90-beta 2, Heat shock protein 90-beta b, Heat shock protein 90Bb.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTU1_CHICK
Sequence: MLRLRCKARSGTQPLPGLTAHSRLRDMQAALAALTGVPAPAQRLLLGFPPRSLDLSDGERRLGELGIHSGDTLIVEEDTSKPSAGSPVVAKRTMAVREAVPVLARRVVPADNSCLFTSVYYVVEGGVYDPGCAPEMRSLIAQIVASDPEAYCEAVLGKTNREYCEWIRREETWGGAIEVSILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLERKIPDSDVPPQTIFSTTDDVVLAQALELADEARRKRQFTDVNRFTLRCMVCQKGLTGQVEAREHAKETGHTNFGEV
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins.  May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore.  Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel.  Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains.  Also able to hydrolyze 'Lys-11'-linked ubiquitin chains.  Cleaves both polyubiquitin and di-ubiquitin.
What are the official names of this protein?
Ubiquitin thioesterase OTU1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_SYNPW
Sequence: MTSTLPSQPSASDLAVSSRPAAAGRFGRYGGQYVPETLMPALAELEQAAAQAWKDPAFTAELNRLLKSYVGRATPLYEAERLTEHYRRADGGPRIWLKREDLNHTGAHKINNALGQALLALRMGKKRVIAETGAGQHGVATATVCARFGLECVVYMGAEDMRRQALNVFRMRLLGATVHPVTAGTATLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMLVRDFHAVIGQETRQQCREAFGRLPDVLMACVGGGSNAMGLFHPFVECTDVRLIGVEAAGDGVATGRHAATITEGRVGVLHGAMSLLLQDQDGQVQEAHSISAGLDYPGVGPEHSYLREIGRAEYGAVTDAEALEALQLVSRLEGIIPALETAHAFAWLETLCPTLSAGTEVVLNCSGRGDKDVNTVAERLGDAL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PP4R4_MOUSE
Sequence: MHPPPPDAGVAMDFGQNSLFGYMEDLQELTIIERPVRRSLKTPEEIERLTVDEDLSDIDRAVYLLSAGQDVQGASVIANLPFLMRQNPTETLRRVLPKVREVLHVASVEMQLTAAVSFLTILQEESMSVHTCAHSFLQVILLHLEHRDTGVSNAWLETLLSAVELLPKETLRHEILNPLVSKAQLSQTVQSRLVSCKILGKITNKFDAHSIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGAELTKNVVLPELIELSRDESGSVRLAAFETLVNMLDMFDTDDRSQTILPLVKSFCEKSFKADESILISLSFHLGKLCHGLYGIFTPDQHLRFLEFYKKLCTLGLQQENGHNESQIPSQIVEQEKKYTSVRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRHTIAICFYEVSKLLNSGVHLIHKELITLLQDESLEVLDALINHLPEILELMSTGGENSVQENKFSSVPDLIPALTAAEQRAAASLKWRTHEKLLQKYTCLPHIISSDQIYYRFLQRMFTIMMTNNVLPVQRAAARTLCIFLRYNRKQEQRHEVIQKLIEQLGQGKSYWNRLRFLDTCEFIIEIFSRSFFCKYFFLPVIELTHDPVANVRMKLCYLLPKVKSALKIPADMHLLQQLEMCVRKLLCQEKDKDVLAIVKKTVLELDRMEMSMDMFQKKNYEKDLLDQEKEREELLFLEMEQLEKEKHQSDGRLASDKSFEKKRRDSRTSTQSLSKNLPISVPGPSSSTASTSKEIKKSKLTRSQSFNNQAFHAKYGTLDKCASKSSTLAHTSSVSGLVRTAMLSLTDDSFRTRNASSVPASFSPNPVMPSTSRGPGNTADPKSSGSKDAQPRKATLKSRKSNP
What is the function of this protein?
Putative regulatory subunit of serine/threonine-protein phosphatase 4.
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 4.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS5D_MANSM
Sequence: MANRIRLHIWGDYACFTRPEMKVERVSYDVITPSAARGILSAIHWKPAINWVIDKIYVLKPIRFESVRRNELGAKISESKVSGAMKRKSVADLYTVIEDDRQQRAATVLKDVAYVIEAHAVMTSKAGVDENTTKHIEMFKRRALKGQCFQQPCMGVREFPAHFALIDDNDPLPLSQLSESEFNRDLGWMLHDIDFEHGNTPHFFRAELKNGVIDVPPFYAEEVKR
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  This protein is a sequence-specific endonuclease that cleaves pre-crRNA at G21 into mature crRNA.  Does not cleave pre-crRNA associated with the T. thermophilus strain HB27 Cas5 protein (AC Q746C2) CRISPR locus (PubMed:23006625).  The reaction mechanism may proceed by an intramolecular attack of the 2'-hydroxyl group of G21 on the scissile phosphodiester, cutting the precursor 3' to G21 residue yielding 5'-hydroxyl and 2' and/or 3' ends lacking a hydroxyl group (perhaps a 2'/3' cyclic phosphodiester) (Ref. 2).
What are the official names of this protein?
CRISPR pre-crRNA endoribonuclease Cas5d, Pre-crRNA processing endonuclease Cas5d.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
Protein: KCY_PELTS
Sequence: MNSFPNIAIDGPAGAGKSTVARLLSKELGFLYIDTGAMYRAVALKAIRKGVDLADQPGLSRLAAVTSVNLKTDAEGNLRVFLDGEDVTEEIRSPAVSKAVSLVARVPAVRERLVELQRAMASGGGVVMEGRDIGTVVLPDAEIKIFLTASPEERARRRREELAARGYIVDQHQMVNEITERDRIDTTRAAGPLVPAADAEIIDCSSMPVEKVVKMIVARVSAGRRE
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURS_BACSU
Sequence: MYKVKVYVSLKESVLDPQGSAVQHALHSMTYNEVQDVRIGKYMELTIEKSDRDLDVLVKEMCEKLLANTVIEDYRYEVEEVVAQ
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurS, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit III, FGAR amidotransferase III, FGAR-AT III, Phosphoribosylformylglycinamidine synthase subunit III.
What is the protein family that this protein belongs to?
Belongs to the PurS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_HAEIN
Sequence: MNNMKTFKFFTALFATAILTACTLDMERPTNVQYIDKTDAIWQQHLQKIQKIQSYQAKGQIGYISPTERFSSRFEWQYQNPKSYTLKLYSLISKSTLWIQMHQSGMTISDNNGNQQSAANSKLLLQEIIGMDVPLEHLAYWLKGQPAMNADYQVGTNHLLGAFTYHVDGSQWTADYLTYHSNNSMPENILLKNDSTKQTLKIRVDEWIY
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: Y3161_HALH5
Sequence: MISQATIFMLVLLVIALLAKNQSLLIAVLVLLVIKFIGVGDKVFPFFQQKGISLGVTIITIAVLTPIATGEIGFKQMGEAIRSSYAWVALLSGVVVALIAASGIDLLKNDPHITTALVLGTILAVAVFNGVAVGPLIGAGIAYLTMKVVQWLGSFWG
What are the official names of this protein?
UPF0756 membrane protein BH3161.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
Protein: OPTN_CHICK
Sequence: MSSKPQIRPAENGEHCRSKMENGMDSMAPPTLSTYTPEEMVQQMKELITENNELKEAMKLHNQAMKDRYEELSIWREKQKEEREFYETKFKEAKQCLLAKCVENEQLQQQLQSLKEREEGAEMEGCATPEKEARQLKSKVQRLQAEKADLLAIISELQVKLNIASAEDSFVEIGMNEEVNRTARENQDNSSEMASNIAVYIRSKSADESKNLESEELTVSQLLCCLRNETQRREKLEKELQDHKERLSKMENETSNCLESGTQTNQEEESSEAIGSEVESLKKQICALFKELQEAHEKLKEAELIQKKLQEKCQTLEKVNSAAATELEEKQQLIYTIKKLELQVESVQAEVKLEQAKTQDEKTRYSSLQDAYNKLLAELTEAMKTISEMKVKEHDRVDKVVVEELNAKVLLAEQALAAKQLQMDEMKQLIAKQEEDLETMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLAVQLAYLLKEQQNLEDLGRSSLAEMQNRHGARAPDREHSPRLVQRGTGSQEWPEQRNISIYSCPKCEEILPDLDTLQIHVMDCIN
What is the function of this protein?
Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death.  May act by regulating membrane trafficking and cellular morphogenesis.  May act as autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family.
What are the official names of this protein?
Optineurin, Ag9-C5, FIP-2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle. Recycling endosome. Cytoplasmic vesicle, autophagosome.
Protein: RAD1_MEDTR
Sequence: MSPALYASTFKCEVDENPSLMGSYYASLYPNLPILENSATSTWILNPFSDHETETIRDHKKLKRSTVTIPIWFANFSSHSNSFFNNINSNNNSVNSIPRLHFRDHIRTYKQRYFASEAVEEAAEDNFNYNNCEAEEDGSCADGMRLVQLLIACAEAVACRDKSHASVLLSELKSNALVFGSSFQRVASCFVQGLTERLTLIQPIGNNSAGSDTKSMMNIMDAASEEMEEAFKLVYENCPHIQFGHFVANSIILEAFEGESFLHVVDLGMSLGLPHGHQWRGLIQSLADRSSHRVRRLRITAIGLCIARIQVIGEELSIYAKNLGIHLEFSIVEKNLENLKPKDIKVNEKEVLVVNSILQLHCVVKESRGALNAVLQMIHGLSPKVLVMAEQDSGHNGPFFLGRFMESLHYYSAIFDSLDAMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHEKVDQWRRRMSRAGFQGSPIKMVVQAKQWLVKNNVCDGYTVVEEKGCLVLGWKSKPIVAVSCWKC
What is the function of this protein?
Transcription factor acting as a regulator of arbuscular mycorrhiza (AM)-related genes (e. g.  STR) (PubMed:26511916).  Required for the morphogenesis of arbuscules upon symbiosis with AM fungi (e. g.  Glomus versiforme) (PubMed:26511916).  Also involved in restricting mycorrhizal colonization of the root meristem (By similarity).
What are the official names of this protein?
GRAS family protein RAD1, Protein REQUIRED FOR ARBUSCULE DEVELOPMENT 1, MtRAD1.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus.