PharMolix/UniProtQA huggingface dataset:
Protein: ERPA_ECO8A
Sequence: MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: HMGH_STRPU
Sequence: MGKKDRDSSKPRGRMSAYAYFVQDSRAEHGKNHPNSPVRFAEFSKDCSARWKALEEKGKGVFHEKSMRDKVRYDREMQSYKPPKGEKNKRRRRRKDPDAPKRNLSAFFIFSGENRAAIKSVHPNWSVGDIAKELAVRWRAMTAGEKIPFDKGAAKDKERYIKAMAEYKAKAKPMKRQVKESSSSSSSDSSSDDSSSDDSD
What is the function of this protein?
Binds preferentially single-stranded DNA and unwinds double-stranded DNA.
What are the official names of this protein?
High mobility group protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HMGB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RPOC_LIGS1
Sequence: MIDVNKFDSMQIGLASSDKIRSWSYGEVKKPETINYRTLKPEKDGLFDERIFGPTKDWECACGKYKRIRYKGVVCDRCGVEVTRSKVRRERMGHIELAAPVTHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVTDAGDTALEKKQLLTEGEYREKREEYGDGFKAAMGAEAIRTLLRDVDLEKECAELKEELREATGQKRTRAVRRLDILEAFLNSGNRPDWMVMDAIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIDVGPKLKLNQMGIPHEMALELFKPFMMRELVKREMASNIKNAKRKIERRDEDIWDVLDDVIKEHPVLLNRAPTLHRLGIQAFEPVLVNGKAMRLHPLACEAYNADFDGDQMAIHVPLSDEAQAEARLLMLAAHHILAPKDGKPIISPSQDMTIGNYYITLEEAGREGEGMVFKDVNEVRTAYQNGYVHLHTRIGLQASSLAKLGTPFTDWQKERILITTAGKAIFNEILPADFPFLNEPTQENLTGMTPDKYFVEPGTDIKEFIKNQPLVGPFKSGFLSDIIAQVYKEYKVTATAELLDRMKDLGYYESTKSGLTVGIADVTVLKEKPEIIEQAHKNVATVAKQFRRGLITDEERYNRVISIWNKAKDDIQAKLVENMDPSNPIQMMSDSGARGNISNFTQLSGMRGLMAAPNGKTMELPVISNFREGLSVLEMFLSSHGARKGMTDTALKTANSGYLTRRLVDVAQDVIIREEDCHTDRGLDVTAITEGNEMIEPLYDRILGRYTMKEVKDPNTGEIIVPANVLVEESEARKIVDAGVQKVTIRSAFTCNTRHGVCERCYGRNLATGDEVEVGEAVGTVAAQSIGEPGTQLTMRNFHQGGVAGGDDITQGLPRVQELFEARNPKGRAVITEVTGVVDTVEENPAERTKEVTVKGETDTRTYSLPFTSVLKVKEGDQVHRGDALTVGSIDPKELIKVRDVLSTENYILREVQKVYRMQGVDISDKHIEIMTRQMLRKVRIMDPGDTDMLPGTLLDISQFKDRNTSAIIEGRIPATARPVLLGITKAALETNSFLSAASFQETTRVLTDAAIRGKNDPLVGLKENVIIGKTIPAGTGMKKYHDIEPEVVNSNVTDGVYSISELEEKINEQQNNVESSN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RS14Z_CLOBA
Sequence: MARKAIIEKWSKTPKYKTRAYTRCRICGRPHAVLRKYGVCRICFRELAYKGEIPGCRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: NQRD_SHEFN
Sequence: MADAKELKQVLTGPIINNNPIALQILGVCSALAVTSKLETALVMTIALTAVTAFSNLFISLIRNHIPSSVRIIVQMTIIASLVIVVDQVLQAYAYAISKQLSVFVGLIITNCIVMGRAEAYAMKTPPMMSFMDGIGNGLGYGAILLSVGVVRELFGNGSLFGVEILSKISDGGWYQPNGLLLLPPSAFFLIGGLIWLIRTYKPEQVEAKG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_RHIBL
Sequence: MTNIRKSHPLFKIINDSFIDLPAPSSISSWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATAFYSVTHICRDVNYGWVLRYLHANGASMFFICLFLHVGRGIYYGSYTFSETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTTLVEWVWGGFSVDKATLTRFFALHFLLPFIISAMVMVHLLFLHETGSNNPTGIPSDADMIPFHPYYTIKDILGLVLMLMALLSLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVVALVLSILVLAVIPLLHTSKQRSMTFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFLIILVLMPLASIAENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS16_THESQ
Sequence: MVRIRLTRMGKRHQPFYRIVVVDSRKRRDGAYIESLGYYNPLKEGEIKIDVERAVEWILKGAQPSDTVRDIFRKFGVMKRVHEIKYGKKEEATAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: H3N01_CYRHA
Sequence: MKASMYLALAGLVLLFVVGYASESEEKEFPRELLSKIFAVDDFKGEERGCKGFGDSCTPGKNERCPNYACSSKHKWCKVYLGK
What is the function of this protein?
Lethal neurotoxin.  Selectively blocks tetrodotoxin-sensitive voltage-gated sodium channels (Nav).  Does not affect tetrodotoxin-resistant voltage-gated sodium channels or calcium channels (By similarity).
What are the official names of this protein?
Mu-theraphotoxin-Hhn2g, Mu-TRTX-Hhn2g, Hainantoxin-III-14, HNTX-III-14.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 15 (Hntx-3) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPB_PROMP
Sequence: MVSTISRQDQNNNDDLNQPSKEGRFGKYGGQYVPETLMPALFELEEAASDAWKDKQFVNELNHLLKTYVGRETPLYEAKRLTEHYQTKTSTSRIWLKREDLNHTGAHKINNALGQALLAIRMGKQRIIAETGAGQHGVATATVCARFGLQCIIYMGAEDIKRQSLNVFRMKLLGAEVKVVTSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPMIVRDFHAVIGEEAKKQCLESFGSLPDILLACVGGGSNAMGLFHPFVKEKSVRLIGVEAAGSGVNTEKHAATITKGSVGILHGSMSLLLQDKDGQVQEAHSISAGLDYPGVGPEHSYLKDIGRAEYGSVTDAEALDALKLVSELEGIIPALETAHAFAWLEKLCPTLDKDTEIVINCSGRGDKDVNTVASSLNID
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: Y1717_FRATH
Sequence: MIIVISPAKSQNFEPIKTAYQFTQPIFKQQIIKLINTLKHYEVEEIEKLMKISPKLAEEVFAKHNSFNPNKYDNSNAKAAIFTFSGDVYKGLEADTLDNKTIEYAQNHLLMLSGLYGLVRPLDLIQAYRLEMGTNIKIDGKILHKYWQDKITTQLNEYFSQQQNKILINLASNEYSQAIDKKSLAVKWLDIDFKENKAGAYKTIGIHAKKARGLMTRYILENRIENVSDIKKFNVAGYQFNPDFSDENLLCFTR
What are the official names of this protein?
UPF0246 protein FTL_1717.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: TILS_HAEIG
Sequence: MDLLSDIEKQLQKATAQAFLIALSGGLDSTVLLSLFAKLCQKQPHLQILSLRAIHIHHGLSPNADSWAKHCQDLCDQFQIPLIIERVQVDKTNGIEAGAREARYQAIKKHLQTQEMLVTAHHLNDQTETFFLALKRGSGLQGLGAMQQQSVLFGMQILRPLLGFTRPQLEDYAQKEKLNWITDESNKDNRFDRNFLRNEILPELRARWAYFDLAVQRSAQHCFEQQQLINDLLSEAFAEHCQIKNQFKLCQFRKYSLAKQTALLRMWLAENQLEMPSKRQLTQLINDVVFAKEEANPQFQLVNKIIRRYQDRLYLTKPFSDLTKYCLKLEQNTLSLPDDLGNLSVQENEHNLIFHWQDFSVTLEKTDLPISIRFGYSGKVKHHPKRPREDIKKIWQELGVPPWERNRIPLIFYGNELKSAVGFFRVFDEY
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_PARP8
Sequence: MAKMQAKVQADERDDGLREKMISVNRVTKVVKGGRILGFAALTVVGDGDGRVGMGKGKAKEVPVAVQKAMEQARRNMFKVPLKNGTLQHEVHGKHGASTVLLAPAKDGTGVIAGGPMRAVFDVMGVQNVVAKSHGSTNPYNLVRATLDGLRKQSTPADIAAKRGKSVEDILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: HE12_DANRE
Sequence: MDIRASLSILLLLFGLSQASPLREFEAIFVSEPETVDITTQILETNKGSSEVLFEGDVVLPKNRNALICEDKSCFWKKNANNIVEVPYVVSGEFSINDKSVIANAISIFHAQTCIRFVPRSIQADYLSIENKDGCYSAIGRTGGKQVVSLNRKGCVYSGIAQHELNHALGFYHEQSRSDRDQYVRINWNNISPGMAYNFLKQKTNNQNTPYDYGSLMHYGKTAFAIQPGLETITPIPDENVQIGQRQGLSKIDILRINKLYGC
What is the function of this protein?
Metalloendopeptidase which participates in the breakdown of the egg envelope at the time of hatching.  Cleaves the N-terminal regions of the zona pellucia glycoproteins ZP2 and ZP3, where it specifically recognizes the peptide sequences TVQQS-|-DYLIK (major site) and KLMLK-|-APEPF (minor site).
What are the official names of this protein?
Hatching enzyme 1.2, Choriolysin H homolog 1, High choriolytic enzyme 1 homolog, zHCE-1.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_ECOSE
Sequence: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RGI1_LACTC
Sequence: MTKKDKKPKISTIVTKEGDTVKVFEDLDTFETFIKNETEDEEFDHVNCHLKYYPPFVLHESHEDPEKIKETVNSHNRKFVRHLHQHVEKHLLKDIRERLQLPQLKFNDKSKEETPDHIVWRYNQRANFHERDFDIHVTVECHHDSALVDVDYLTVPVPAVAAA
What is the function of this protein?
Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.
What are the official names of this protein?
Respiratory growth induced protein 1.
What is the protein family that this protein belongs to?
Belongs to the RGI1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RSMH_RICRO
Sequence: MIQSHVSVMLNEMLEALSPKAGESYLDCTFGAGGYSKAILESCNCYVTALDRDPNVIKRAEEIQQNYGERFDFVETNFADSFAKLKEKKFDGIVLDLGVSSMQLDIADRGFSFLHDGPLDMRMSGQGLSAEEFVNAAEEKELADVIYKYGDESFSRRIAKRIVEYRKTARIDSTGKLAEIVRSSIGFRKGKIDPATKTFQAIRIYVNDELGELEQFLVNVKNILKKDGRLVVVSFHSLEDRIVKNFFKENSEKPVVRSKYAKDDMTIDPNKWLKIITNKALAPSDKEVGLNIRARSAKLRAAKAIYE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_PROM0
Sequence: MIQQETYLTVADNSGAKRLQCIRVLGSNRRYAHVGDVIVATVKDALPNMGVKKSEVVKAVIVRTKATLRRNTGNSIRFDDNAAVLINEDKNPKGTRVFGPVARELRDKNYTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: EF1A_METMA
Sequence: MAADKPHMNLAVIGHIDHGKSTFVGRLMYDAGAVPAHIIEKYKEEAKQKGKESFAFAWVMDSLKEERERGITIDIAHKRFDTDKFYFTVVDCPGHRDFVKNMITGASQADAAVLVVAAPDGVMAQTKEHIFLSRTLGINQLIVAINKMDAVDYSEARYKEVVEQVSGILKMIGFKPSEIPFIPTSAFHGDNIMKLSDKTPWYKGPAIMEALNSLKEPEKPSTLPLRIPVEDAYTISGIGTVPVGRVETGVMKKGDKVVFMPGGAGGEVKSIEMHHEEIPQATPGDNIGWNVRGIGKNDVRRGDVCGHADNPPKVADEFVGQIVVLQHPSAITAGYTPVFHAHTSQIACQLIALNKKLDPKTGQVKEENPTFLKAGDAAIVTIKPTKPMVIEPVKEIPQLGRFAIRDMGMTIAAGMCMSVKQK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_NITHX
Sequence: MQVLVRDNNVDQALKALKKKMQREGIFREMKLRGHYEKPSEKKAREKAEAVRRARKLARKKMQREGLLPMKPKPVFGAGPGAGRGGPGAGARPPR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: EFTS_WOLSU
Sequence: MAEITAQLVKQLREMTDAGMMDCKKALVETDGDIEKAVEYLREKGLSKAAKKADRVASEGVVSVEVASDFSKASLLEINSETDFVAKNEQFKELVAKTSKLVHDHALSSTETLHTVSVDGMEFSEYLQQNIAKIGENIVVRRIVTLETKRGAIVNGYVHSNGRVGVLIGIKFGKEGSKSACVELARNLCMHAAAMKPQVLSYEELDPEFITKEKVALIAELEKENEELKRLGKPLHRIPEYISRSELTPSVLKNQEQKLREELKAQGKPEAIWDKIVPGQLERFIADSTLIDQRLTLLGQFYVMDDKKTIAQVLEAKGKELDDSIEIVDYVRFELGEGIEKKACNFAEEVAAQLG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5C1_PAUCH
Sequence: MLRRAVELVWLIPILPFIGAFLVGFGLISFNKKVNQLRKPAALLLISSVGISAVLSFMVLADQIGGAPCSEVLFSWASAGTFNLEMGYRVDPIGATMLALVSTVAILVMVYSDGYMSHDKSYVRFFTYLGLFTSSMLALILSPNLLEIYVFWELVGMCSYLLIGFWYEREDAANAAQKAFVVNRVGDFGFLLGILGLFWATNSFDFQIVATKMAASISDGSIPHWAAIALCLLLFMGPMAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARLEPLYSQVPDVQIIVAVIGTITCFLGASIALIQMDLKKGLAYSTISQLGYMMLAMGCGAPVAGMFHLITHAFFKAMLFLGSGSVIHAMEEVVGHDPTLAQDMRLMGGLRKTMPITGITFFIGCVAISGIPPLAGFWSKDEILSKAFDSYPLLWGVGLFTAGLTAFYMFRLYFLTFEGEFRGNNIALREKLLIAAGKSFDPIETKEIQSTHESGWQMTLPLVILSVPSVLIGFLGSPWNNRFGMLLYPEEALEAAKTFSWGEFLPLAIASVMISTCGIVIATIAYAYHWIDLGQSVASRLKIINNFLVNKWYLDKINEYIFVNGSRGLAKKILNLDETVLDKAVVETGLTTLDAGKWLSYFETGRPQFYALIIFGGVISLIVIFNRL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, organellar chromatophore 1, NAD(P)H dehydrogenase subunit 5 1, NADH-plastoquinone oxidoreductase subunit 5 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore thylakoid membrane; Multi-pass membrane protein.
Protein: GLYA_ACISJ
Sequence: MYQRNILVEQTDPEVWAAIQAEDRRQEEHIELIASENYASPAVMAAQGSQLTNKYAEGYPGKRYYGGCENVDVIEQLAIDRIKQLFGAEAANVQPNSGSQANQAVLMAFLKPGDTILGMSLAEGGHLTHGMPLNMSGKWFNVVSYGLNDKEEIDYDALEAKAREHKPKLIIAGASAYALRIDFERFAKIAKEVGAIFWVDIAHYAGLVVAGEYPNPVPFADVVTSTTHKSLRGPRGGIILMKAEHEKAINSAIFPGLQGGPLEHVIAAKAVAFKEALSPEFKQYQQQVTKNAKVFAETLIQRGLRIVSGRTESHVMLVDLRAKGITGKEAEAALGKAHITINKNAIPNDPEKPMVTSGIRVGTPAITTRGFKEEETRLTANLVADVLDNPHDEANLEAVRAKVHALTSRFPVYR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_CAMJR
Sequence: MNIIEGKLNLDSNTKIAIINARFNHIITDRLVEGAKDAFLRHGGKEENLSLILVPGAFELPYALKKAIESKKFDAICCVGAVIRGSTPHFDYVSAETTKGIANVSLNHNIPVSFGVLTTDTIEQAIERAGSKAGNKGFEAMTTVIEMLNLSKEL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: AUSY_EMENI
Sequence: MQSSLLGRMTGVTGSRSKRHTKFRLRRLQQPPTESTTRLASPDDAQPIEETKSQEHLEQSATQGLSEASGDNNAGGAHPTPAPNEGDAPTVAELQHGSNDRVDDGTSGSGTVSGWKLAAVLIGLSLAVFCMSLDSTVLSTAIPKITAEFNSLHDMAWYVSAYNLTISSFSLVYGKIYSLYRVKWVYLTTLFLFEAGSLVCGAAPSSLALIIGRAIAGVGGAGVFLGSMLIVHEIMPLHQVPLFIALISGLYGIASVVGPLLGGVFTDYVSWRWCFYINLPIGGLTAFIIVLFVRPRVREKATVKKTPWAQLLDLDPLGIILILPAVMCMLLVLQWGGAKYAWSNWRIIVLLVMAGSLALTFTAVQLWQGERATIPPRIVRNRSVWGAIAFSVCIYGSFTVFTYYLPIWFQAIKSVSATRSGVMNLPMILGVVVCSMLSGWGVSRVGYYVPFMYMAPVVGSIGAGLLTTLHVFSGPAAWITYQLLLGVGIGSGMALPLVAVQTALPTDDVSTGSAIITFTQSLSGALFNFVAQSVFQSRLVHNLNAALPGVDTARVADVSPREIRNAIEPEYLPQTLEAYSLAITQVFYAGTALCTLALFGVLPIKCLSVKGSRIPPMAHA
What is the function of this protein?
MFS-type transporter; part of the gene cluster B that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids.
What are the official names of this protein?
MFS-type transporter ausY, Austinoid biosynthesis clusters protein Y.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TATB_NITHX
Sequence: MFDIGWSELVVIAVVALIAIGPKELPGVLRMVGQWMGKARRMAAEFQGQFNEAMREADMAELKKSFDEVRDATSGLTSGNLMTKLTDSLGEPPKLEDLDKPAANRPAADMSAASANDVPASGSIAPEAAIPKTGTEADAKALASEPLAITPEFQHATPEPAPATHETPHEAVKDAKAS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PROAY_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGTMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-3, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y5399_BRASB
Sequence: MTILKWALLFFVISVVAGILGFTGISAASADIARILFYIFLVIFLVLLILGLTIFRV
What are the official names of this protein?
UPF0391 membrane protein BBta_5399.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TEY_DROME
Sequence: MESNAFGSSHLPSQALVVLSEAASGLHEALRGQRPFPSRVIPFDFPLLQLPDAKDLHNMSLVGNYFNPHLLLNHGMLVANGAAAAAAAAGAGPASYFASDRSPLGKPSVLSNFSLPSAFSPPKYIGISLDQNLFNGSESFRTDSASPTCTSHESMEGSQDYDAVEKGESPRSNNSQDPRDLRHLHNAGKSHQALATSSSASSSSSSSCSTSNPAISTATSSVAVSMASHLAASSPHHHPHTHAHSHPHPLAHPHAHSHHHVGHHVGAPPVSTAVTTHHHMAHPHPLSHHHAAHHAALASLSMAGLRAVPGGLSLVSGLQAAAAGGAIPEMCPVCGLKLSAEEWHTHFLTELDRLYKLSAGFERASLQATYMFAPPCPAQENAIRTSHNRWETFQRIRNNRQNRLRLKVRKRKYGEMYMMESLYCSSCPICKRKYALETGKIPPEDDAKSQEEIETVDVESCNDEVPDSGSELATPSSGSSGTVMPPSSMHNSNSQPGKLDGILYRTGCVLSQKDPHPDEHDVSTNVTTASSSSWPGEAPTQAHISVKTVSELSSTTHHYYNADSCGVGVNDTNSSSSTHNNGGGSNKDLMMDTASCQNDSDEDVIVDDDDTVKLTSKINYGKIQRRQDEQNVGSSRSLENISPVEERPRSEPQVSSTEPGPMDISHNNNNNNNNNNNNSNSNNNNNPSTKYAESMENSLSQLSSMGVPGLTQLDTKA
What is the function of this protein?
Required for the correct synaptic targeting of motoneurons RP5 and V to muscle 12 (M12) (PubMed:20504957).  May be involved in the negative regulation of Tl in M12 (PubMed:20504957).  Involved in the correct patterning of veins in the proximal (costal) region of the wing blade (PubMed:17028348).
What are the official names of this protein?
Protein Teyrha-meyrha.
Protein: Y1276_MYCS2
Sequence: MAQLVRDRIPELIRASGRTPVIRTLSDDEYWAALDAKLDEEVAELRAADTRDAALEGGRHRHRGESASGNGIQHGVPPNVALIPSGSTLLTPARSGHV
What are the official names of this protein?
Uncharacterized protein MSMEG_1276/MSMEI_1238.1.
Protein: PDXJ_RALPJ
Sequence: MIFHASPGIIDLGINIDHVATLRNARGTTYPDPIAAALLAEEAGADLITLHLREDRRHIKDADVRALRPQLRTRMNLECAVTQEMLDIACDIGPQDVCLVPERRQEVTTEGGLDVVGGFAKVQAACKQLADAGIRVSLFIDPDAAQIEAAAAAGAPVIELHTGRYAEATDDAELRAELVRIETAVEEGIRWGVRVNAGHGLHYTNVQPIAAIAGIHELNIGHAVVAHAVFAGWQNAVREMKAIMVAARLSSTTPAAAHPGVPV
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.