PharMolix/UniProtQA huggingface dataset:
Protein: HEXB_STRR6
Sequence: MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKYMKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSAKKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPDALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLTLFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENHTSLRELGKY
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  The hex system is nick-directed.
What are the official names of this protein?
DNA mismatch repair protein HexB.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: PA2H7_TRIGA
Sequence: MRTLWLMAVLLVGVEGGVIELTKMIVQEMGKNALTSYSLYGCNCGPGGRRKPMDATDSCCYVHKCCYKKLTDCDPIKDRYSYSWVNKAIVCGEKNPHLKELCECDKAVAICFRENMDTYDKKKKINLKLFCKKTSEKC
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks enzymatic activity (By similarity).  Is myotoxic and displays edema-inducing activities (By similarity).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog 7, svPLA2 homolog, Phospholipase A2 isozyme VII, PLA2-VII.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GPMA_STRP2
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: NDK_PYRFU
Sequence: MNEVERTLVIIKPDAVVRGLIGEIISRFEKKGLKIVGMKMIWIDRELAEKHYEEHKGKPFFEALIDYITKAPVVVMVVEGRYAVEVVRKMAGATDPKDAAPGTIRGDYGLDIGDAIYNVIHASDSKESAEREISLYFKPEEIYEYCKAADWFYREKKQAKC
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_PECAS
Sequence: MEFTTRTIPAQKHIALVAHDHCKQSLLDWVGTNKQQLTEHTLYATGTTGNLIQSNTGLPVKSMLSGPMGGDQQVGALISEGKIDLMIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNRATADFLINSALFKEPVQIAIPDYQRYLQDRLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: Y669_STAAM
Sequence: MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKLIDALEDLEDVQNVFHNVDLK
What are the official names of this protein?
Probable transcriptional regulatory protein SAV0669.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOC1_CHLRE
Sequence: MRVLGFLSSHAGTGTAAAHTRWRWLAPLGIQAIRPASASAGGNAVSSATPQAPPCPIHANVGVGRASALGPGPSGFMAPSAGIVTAIRDGPNSNSRCSTVRTHATRSKSTGPSRATSSGPATAAPPRRRRRTSNDTQDGGLTSEQTPTNTAVAAVAATAAAAAGASASAAAPALPVALNPTWRTPPTAEAARRITQAASASAAYSGSSAAAAAAAVAAGPSSAASVARGGSAAAARSAAASALAANANTSSGAASAAAIAATASTAPGKLLLGGDLSRALAAAGSTTAPPLPLPSRAGLSAPKHTASAAAAAAAAASVLPASTPAAASQTPPTTVTSCGTGSGAPATPRAARSPTAAVSVSSADAAAAAAAAAAPASAAATAAAAVLPTRHIVAAVDPDLNGALALIYWDEDPNDPTTATASGPAAATTDAAAAAAAAAAAATGPAARLATLAAAAPPGSGAAAAADEAAAAALLWLPTPPRPPADASRWRVCVWDMPVSAAERQKRTASGQVARRRLLHVAGARAVLSAALAAALPPPGEARPVALYGYVEVPPILPGDGNIAAYTSLWSTGSWLGLLTGMGFTVGSTPVRRWKTDLGLYGAKGKDASLALARALFPGQQPILRHKKNHGRADALLIAAWALGACLPRGLGASLRRNGITLDQLLQQQPGTTVGLVWGPPRPPAPTDAYGNLLTPEQDMWDEIEAAETKVERKAQARSSTARRRKTAGTQEEPEAQAEEEQAEAGTGVVAAAAGAAAPKRRRAKKAAVESGSEAAVAEVAAGPQEEGSEGEVAGQGGRACRSKSRSKSSGKSSSKAEAGGAGSGRRRAASVGSSSVGSSSVGSSSGGGGGGGGGVKAPGASRRRGGAKAGSDGGVSGSESE
What is the function of this protein?
A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination.  Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products (By similarity).  Mediates chloroplast nucleoid segregation during chloroplast division (PubMed:28495749).
What are the official names of this protein?
Holliday junction resolvase MOC1, chloroplastic, Protein MONOKARYOTIC CHLOROPLAST 1, CreMOC1.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NCAP_MABVR
Sequence: MDLHSLLELGTKPTAPHVRNKKVILFDTNHQVSICNQIIDAINSGIDLGDLLEGGLLTLCVEHYYNSDKDKFNTSPIAKYLRDAGYEFDVIKNPDATRFLEVIPNEPHYSPLILALKTLESTESQRGRIGLFLSFCSLFLPKLVVGDRASIEKALRQVTVHQEQGIVTYPNHWLTTGHMKVIFGILRSSFILKFVLIHQGVNLVTGHDAYDSIISNSVGQTRFSGLLIVKTVLEFILQKTDSGVALHPLVRTSKVKNEVASFKQALSNLARHGEYAPFARVLNLSGINNLEHGLYPQLSAIALGVATAHGSTLAGVNVGEQYQQLREAAHDAEVKLQRRHEHQEIQAIAEDDEERKILEQFHLQKTEITHSQTLAVLSQKREKLARLAAEIENNIAEDQGFKQSQNQVSQSFLNDPTPVEVTVQARSINRPTALPPPVDNKIEHETEEDSSSSSSFVDLNDPFALLNEDEDTLENSVMAPSTTLREPKEVSEPLRQTQDLDISQKKQGNESTDPARKQFLRYQELPPVQEDDESEYTTDSQESDDQPGSDNEQGVDLPPPPLYAQEKRQDPIQHPAVSSQDPFGSIGDVDGDILEPIRSPSSPSAPQEDTRMGEAYELSPDFTSYEDNQQNWPQRVVTKKGRTFLYPNDLLQTSPPESLITALVEEYQNPVSAKELQADWPDMSFDERRHVAMNL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication.  During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein.
What is the protein family that this protein belongs to?
Belongs to the filoviruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RGLB_ASPNC
Sequence: MRLLHPLIPASLLLTLTSATLHTSQTNTTITLTNNRLTANFSKSQGRITDLYLDNQDLLGPQSGDTGVGPYLDCYCIPSGFYTPGSTSPTLQLFTGTDKSGTSYAGVLMDETYPPTGQHFQQYWFLRDGETGLHTFSRLAYYNETTPYLRNLQEFRTLFRPNTELWTHLSSSEVQTAPLPSKKAVEEEVVVQDATWTFNNTPTDEYYVQFADYFTKYTFSNAWRDNSVHGMYADGSTSNGSTFGAWLVMNTKDTYYGGPLHSDLTVDGIVYNYLVSNHHGEGTPNITYGFDRTFGPQYYHFNGGKGSTASLQELKSDAETLADPSWNVDFYDSIAKHVVGYTPSSQRGSVQGKIKLPKGATRPIAVLTVDGQYFQDNSVNSSSYQYWAEIDDSGHFSVDHVKEGPYRLTVYADGIFGDFVRDGVQVKAGKKTTIQETWEAESAGTEIWRLGTPDKSSGEFRHGVARDPTHPLHPPEYLIYWGAYDWQSDFPDGINYTIGTSDPATDLNTVHWSVFGPTPNDPRVEYDTTHDWTINFPLSEDDLAERSKATLTIQLAGAKAASGNTDVYNASEPYTNLALESYINDQAEPLTLLIGFNQSSSCIVRSAVSCYQVRSRMEFPADWLKVGNNVLTLHLPYNATDTETAILPATVTGRLILPPQPIYGQTPVILSVIGSEKLEPLPAASILIFEIIRHQSEPLWSVPRSA
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity).
What are the official names of this protein?
Probable rhamnogalacturonate lyase B.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECR_LATSS
Sequence: MQYPEPIAKLIESYMKLPGIGNKTATRLAFYTIDMNEDDVTNFAKNLISARRDLHYCSVCGNITDEDPCEICRDTARSQEMILVVEQPKDVMSMERMNDYHGLYHVLHGVLSPIEGKGPDDINIANLIKRLQKTPAKEVIIATNATPEGEATAMYISRLIKPAGIKVTRLAHGLAVGSDIEYADEMTLLKAVEGRQEI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: SYMM_DROME
Sequence: MLIRRIKCLRYLGTRYNSSHYVTTPIFYVNAAPHIGHLYSAVIADAHCRYQRLRYPEQDVRLCTGTDEHGTKIQQAASLHGVPVAKYCDDISQRYREVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIYSAAYSGWYCVSDETFLTDSQLRLDEATGTRYSLESGHPVEWTEETNYMFRLSQFQDDVRHWVKTEARVRPAKFEKILLDTLSEPLPDVSVSRPSNRVHWAIPVPDDDSQTVYVWLDALVNYLSSVGYPDEKFSAHWPPAQQVIGKDILKFHGIYWTAFLLAAGLEPPGQLYVHSHWTVDGQKMSKSKHNVVDPLQAAQQYTMEGLRYFLLREGVAHSDGNYSHVKAQRILNSELADTLGNLLSRASAKSLNPGQIYPSPSAEHLADLLRSLDVAKRLQDSLLQLSERCESHYECNHFHLVADTTMAALHAANNFFESSKPWTLKAGAPDGNQARLETIIAMTMDALRLSGIVLQPIIPQLANRLLDKLSVPTAQRGWNYLAESFATSPNSSNSPAGLGESRQLDGQTSALLFQRILEETSAKEVKEQKPQPAKRSKSKKKERRETMS
What are the official names of this protein?
Methionine--tRNA ligase, mitochondrial, Mitochondrial methionyl-tRNA synthetase, MtMetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MOAC_BACC7
Sequence: MSSFTHFNDQGRAKMVDISDKKATVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQIAGIMAAKRTSDIIPMCHPLLLKGVDVSFDWKQSDEQYRLLIEVKVKTEGSTGVEMEALTAASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYARKS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: DAPH_LACCB
Sequence: MAQLDTQKIISTIANSKKTTPVKVYLKGKLSELHFPKSVHAFIGKHTGTVIGDWAEIKPILKKAKLDDYYVETAGRNTGVPLLDIKAANARIEPGAIIRDQVLIGDNAVIMMGAIINIGAEIGAGTMIDMGAVLGGRAIVGKHCHIGAGTVLAGVVEPPSAKPVTIGDHVMIGANAVVLEGTTVGEGAVIAAGAVVINDVPAHTVVAGVPAKVIKQVNDQTEAKTVLLDELRKL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: GLNA_SCHPO
Sequence: MSQYDVEPLLSKAAILNKYADLPQNGKVMAEYIWIDGFNHLRSKTMTLDAKPSSIDQLRVWNFDGSSTGQAPGNNSDTLLKPVAMYNDPFRRGDNILVLAACYTADGSPNGFNHRDACAKLLEKHADKETWFGIEQEYTMLDYYDRPFGWPKGGFPGPQGPFYCGVGTGRVFARDIVEAHYKACLYAGINISGINAEVMPSQWEYQVGPCAGIEMGDQLWMSRFLLHRIAEDFGVKISFHPKPILGDWNGAGCHTNVSTKDTRAEGGIKAIESYLEKFAKRHKEHIAVYGDDNDLRLTGRHETGSIDKFTYGVADRGASVRIPRSVAMNGCGYFEDRRPASSIDPYLVTGIITETMFEH
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_STRMK
Sequence: MSDAEDIPTGRKRRPREQTPVQRALGLLVRREHSRKELTRKLTARGIEDEAAQAAVAKLTEAGWQDDTRFAENLVRMRANTGYGPIHVRAELGTHGLDSAAIAAAMDSYEGDWQENARDLVRRRFGEAGPQDLTQRRKAADLLARRGFDGDSIRRATRYDPDD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRI1_SCHPO
Sequence: MSKLPSPTMPLPESVGDLVVLHFETNLDDHGISIGRAPCEIHEICWVILDGKTLEKQHCESCSIREDSSRHGICGSASSLTEAIFTLDNSIQERLNFQGKPFTFVVMNGRELRVLLPKEARDQGITLPSYMRHPRLFDLSSEYAKWQIRMGAVPPYTITLSHIFGKLDVDSLPPITESKAIELSPSDAPYITKGLTQCWRLANATTLLLRKAEKDSRGHSLPSVLTQPINCQADARSFYAERSKIVHVAGLTNDVTQLELESWFTNHGVHPVALWTLKTPEPYKSTGTGFVLFASHEDAADALAFNGYCLGDRMLEIIPSSTKVLDKASDILIPFPSSKNRPRPGDWNCPMCGFSNFQRRTSCFRCSFPGPTHVSAATGSNTFSPDFPYGNSYGNGSSHFIANYGGSVHHSNENTMQSDLQHQNGNNAVNHHHSSRSFGGNVPFRAGDWKCGSEGCGYHNFAKNVCCLRCGASRATAAVVADHASGPVNGSYSHNSYSHIPPVMSTSPPNHSVYPYSQLSINSVTANHGQNFGGQNGGNVSRFDDHGRFKEVSRPSVTTDQGDWLCECGFTNFRRRSNCLRCNAPHYSNMQIPASLPSDFNAYV
What is the function of this protein?
Mediates heterochromatin assembly by promoting RNAi-mediated heterochromatin silencing and histone deacetylation (PubMed:33693625).  Binds pericetromeric transcripts and recruits the RNA-induced transcriptional silencing (RITS) complex to heterochromatin (PubMed:33693625).  Recruits sir2 to chromatin to promote deacetylation of 'Lys-9' of histone H3 (PubMed:33693625).
What are the official names of this protein?
RNA-binding protein involved in heterochromatin assembly dri1, Dpb4-interacting, RRM, and IDR-containing factor.
What are the subcellular locations of this protein?
Chromosome. Nucleus.
Protein: CHBG_SALSV
Sequence: MERVLIVNADDFGLSKGQNYGIVEAYRNGVVTSTTALVNGEAIGHAAQLSRELPALGVGMHFVLTLGKPVSEMPGLTRDGLLGKWIWQMAEEDTLPLDEIAHELACQYQRFIDVFGREPTHLDSHHHVHMFPQIFPIVARFAAQRGIALRIDRQTVLNADDLPSDLRSTQGFSSEFYGEEITEACFLRILDASAHRGEASLEVMCHPAFVDNIIRQSAYCYPRLTELEVLTSASLKAAIAERGYRPGSFLDI
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_CHLFF
Sequence: MKEKTTQLYEGAYVFSVTLSEEARRKALEKVTSGIINYGGEILKIHDQGRKKLAYTIRGAREGYYYLIYFSVVPGVIAELWKEYHLNEDLLRFLTLKTDAVKEVLEFASLPE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: FABH_MYCTO
Sequence: MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDEWIYTRTGIKTRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPAAPMVAASLGAKGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLSPTIDMYDRGNCFIFADGAAAVVVGETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFVRLEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINELLVKNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGYGAGLSYAAQVVRMPKG
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Mycobacterial beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRHAO_KUEST
Sequence: MLNKSAALVPVVLAFLFLFLCFQCLYADIRCLTGKDGAVHLEMEAKPLTIEPRPGVFFDAWGYCLKGDVPTVPGPVIKVREGTKVKILFRNKLTVPASIHPHGVKYTTANVGVNIAGNPASIVAPGDSRIFEWDTAGTPGTWFYHSYVFERGGEEGLSRGLWGALIVEPVGGDPNPPDKEFVVFMHAFNVNGQEYYAFNNKSGDIELMRGDSSAFPGETWKAKMGDKVRFHLINITEEAHTFHTHGHRWLDKSCDKLIDTIGLNPFDSYVLDFVAGEGVGKGNWAFHCQSQEHMMNGMFGIFMVEEGKRVNAVIASCDEGRKTLSAPGQDRQPPTLEGFSGAYMYPEITEKNMYESFAGLEKGDGIWGDYYSPIPLYTYFNPSRHYVPPESDAYTNLLVKYRPDQCVECHEETTPGIVAEWKMSNHANPKKNPHVSAETQEIEALIGKELNNWRPGTKDGVYCSYCHGSDHEKLFMPTVDNSCGACHPKQAAEFIKGRDHGRPNHPQSWEGNVSTPWYAEYYRRGEGYSMVGCDQCHQNMSSCDDCHSRHRFSAAEARRPEACSICHMGPDHPDWESYSRSKWGVIYETTKERWNWDKNLAEVIPGEDYLAPTCQYCHMYVGNNKWEMNVETKGIWRMGVIPPKEVEFKSGLKDFPYGIKIPPMDKKLEIYSAESQEKRRKWVELCSKCHSSRFAGMWLDSLDQYMFESWRRIDEAQLIIEKLFSENAIEPPPEKRPPFPLSDLIIKVLGAEKLGAEMYRLFKQTNGHLPVIGPILGAYSIFTQNEGNPGGIEREYAEMWFWSHLQGYKGAAHAQPDISWWWGTAQGVGNLTRIRDEAEKLRRLKSGSSSGF
What is the function of this protein?
A nitrite reductase-hydroxylamine oxidoreductase protein that probably functions in the type 1 encapsulin nanocompartment.  Probably involved in reductive catalysis.  Targeted to the encapsulin nanocompartment by association with the diheme domain of the encapsulin shell protein (AC Q1Q6L7) (Probable).  Catalyzes the reduction of nitrite to nitric oxide (NO) (By similarity).  Catalyzes the oxidation of hydroxylamine to nitrite (By similarity).
What are the official names of this protein?
Probable nitrite reductase-hydroxylamine oxidoreductase fusion protein, NIR-HAO.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Encapsulin nanocompartment.
Protein: NHR10_CAEEL
Sequence: MTGGGPSSNNSSQPEEVCLVCSDISTGYHYGVPSCNGCKTFFRRTIMKNQTFSCQFQGKCPVDKSIRCACRHCRFEKCLQVGMDRNAIQQNRDPIGYTKRTRRYPPIKKVEASDECSPAMVSENDRSEDNFLTLLSSTEQKCCALRLAEYMPSRTLIEAVVSDCLLTDEVFMAEHAILSPRHRVTSLRFANQSDYHYWHERDWFVMIEWAKTLPVFQSLPFTDKLALLRHSAITYPSLVHVFNSPDHGLDTIVFPDGAYFDRTPEPTRPLGFNKKKYQMLDQLLKPMRSMEIDMTEFAAFKAIFFLNPDADDVDSNAKKTLSDGRSAITNALYRYMVKKKGAEDAGDRFGRLLLLGTVLATMAVEMKEAVLVADFFDQIQFSTFAKQLLFGIKTE
What is the function of this protein?
Probable transcription factor that acts in a feed-forward loop with nhr-68 to activate genes involved in the vitamin B12-independent breakdown of the short-chain fatty acid propionate (PubMed:30625328).  This pathway is triggered in response to a diet low in vitamin B12, when canonical vitamin B12-dependent propionate breakdown cannot function; the resulting accumulation of propionate is probably sensed by nhr-10 and/or nhr-68 (PubMed:30625328).
What are the official names of this protein?
Nuclear hormone receptor family member nhr-10.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARLY_SHESA
Sequence: MALWGGRFQGETSALFKLFNDSLPVDYRLFEQDVVGSIAWADAIASVGIITATECSDLKKALNELLVEVKGDPAIILASGAEDIHSFVESALIAKVGDLGKKLHTGRSRNDQVATDLKLWCQSEGAALVARLQTLRSELIALAEREFDAVMPGYTHLQRAQPVTFGHWCLAYVEMIERDLSRLTDALKRANTCPLGSGALAGTAYQMDRHALAAALNFASPTLNSLDSVSDRDHVVELCSTASISMIHLSRMAEDLIFFNSGEAGFISLSDEVTSGSSLMPQKKNPDALELIRGKTGRVYGSLVGILTTMKALPLAYNKDMQEDKEGLFDVVDSWAICLDMAALVLSGLVVNRPNALLAAQQGYANATELADYLVSKGMPFREAHHVVGVAVVAAIAKKIPLEGFTLAEFKTFADIIEDDVYPNLTIEACLAKRDVLGGTALTQVKQAISAKKIV
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMAS2_MYCTO
Sequence: MTSQGDTTSGTQLKPPVEAVRSHYDKSNEFFKLWLDPSMTYSCAYFERPDMTLEEAQYAKRKLALDKLNLEPGMTLLDIGCGWGSTMRHAVAEYDVNVIGLTLSENQYAHDKAMFDEVDSPRRKEVRIQGWEEFDEPVDRIVSLGAFEHFADGAGDAGFERYDTFFKKFYNLTPDDGRMLLHTITIPDKEEAQELGLTSPMSLLRFIKFILTEIFPGGRLPRISQVDYYSSNAGWKVERYHRIGANYVPTLNAWADALQAHKDEAIALKGQETYDIYMHYLRGCSDLFRDKYTDVCQFTLVK
What is the function of this protein?
Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.
What are the official names of this protein?
Cyclopropane mycolic acid synthase 2, CMAS, Cyclopropane-fatty-acyl-phospholipid synthase, CFA synthase, Cyclopropane fatty acid synthase, Mycolic acid methyltransferase, MA-MT, S-adenosylmethionine-dependent methyltransferase, AdoMet-MT, SAM-MT.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALE_HAEIN
Sequence: MAILVTGGAGYIGSHTVVELLNVGKEVVVLDNLCNSSPKSLERVKQITGKEAKFYEGDILDRALLQKIFAENEINSVIHFAGLKAVGESVQKPTEYYMNNVAGTLVLIQEMKKAGVWNFVFSSSATVYGDPKIIPITEDCEVGGTTNPYGTSKYMVEQILRDTAKAEPKFSMTILRYFNPVGAHESGLIGEDPNGIPNNLLPYISQVAIGKLAQLSVFGSDYDTHDGTGVRDYIHVVDLAVGHLKALQRHENDAGLHIYNLGTGHGYSVLDMVKAFEKANNITIAYKLVERRSGDIATCYSDPSLAAKELGWVAERGLEKMMQDTWNWQKNNPKGYRD
What is the function of this protein?
Involved in the metabolism of galactose.  Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD.  By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H. influenzae.
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: TRUL_CAEEL
Sequence: MTSQPTSSLQGSCSICFEDLKQNDKISAIVCGHIYHHGCISQWIATKRQCPSCRRTVPKNGFVEKLFFDVQRMGGEAEKPPEIDYREEHYKLSTSLKVEQEKLGTLNTENKNLKDTVKSLEKKIIREKDKYRQEIPKLQATINHLTISSEETAYLKRELQESKNRLKTCEFYKILTVHSSEADKQLGEYLKKNGNLDTEKFFQLMKSTNKDLTDKRREAAKEIEQLKMEVQSLKRAAQEDAAIKKTLKKTVLDLRERANVDTPINNKRLRDVLETETPPPAKRKSMGFDESSQMIDPDGELSFFKQNENRTPVTSVPSTSKAVLPFNFDDDEDDEYFKTPKIAEKKKKLPEAMAPVSEDSFDFDIAVPQSIINRIPAKTTAQPAKKYPKIPNLSAKTSSKPTEAPKTENVLKIKSKSQEIAQKPQKSTRISSFFSRTTSSTSNLTEYVILD
What is the function of this protein?
E3 ubiquitin ligase that acts as a key regulator of DNA repair in response to replication stress (PubMed:31545170, PubMed:30849395).  Acts by mediating ubiquitination of the CMG helicase complex, promoting the unloading of the CMG helicase complex by the p97 ATPase (cdc-48. 1 or cdc-48. 2) (PubMed:31545170, PubMed:30849395).
What are the official names of this protein?
E3 ubiquitin-protein ligase trul-1, Traip ubiquitin ligase 1.
What is the protein family that this protein belongs to?
Belongs to the TRAIP family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.