PharMolix/UniProtQA huggingface dataset:
Protein: MEND_SALSV
Sequence: MSVSAFNRRWAAVILEALTRHGVRHVCIAPGSRSTPLTLAAAENPAFIHHTHFDERGLGHLALGLAKVSQQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQAGMFSSHPSQTLSLPRPTQDIPARWLVSTIDNALAMLHAGALHINCPFAEPLYGDMNDTGLVWQQRLGDWWQDEKPWLREARRLASDKQRDWFFWRQKRGVVVAGRMSAEEGKKVAQWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKAVTELQQAQIVVQLGSSLTGKRLLQWQATCEPEEYWVIDNIEGRLDPAHHRGRRLIAKIADWLEMHPAEKRKPWCVEIPRLAELAWQRVVAQRDTFGEAQLAHRIRDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASAKSTLAIVGDLSALYDLNALALLRQVSAPFVLIVVNNNGGQIFSLLPTPQSKRERFYLMPQNVHFDHAAAMFNLRYHRPENWEELESALAGAWRTPATTVIELVVNDTDGAQTLQQLLAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: Y5021_RHOPT
Sequence: MSNPEPDDSNNRIVAVTLDEESIGRSGPDIEHERAIAIYDLVEKNLFAPEGAGEGPFTLHIGITGNRLMFDIRREDGAPVITHLLSLTPFRRIVKDYFMICDSYYQAIRTATPDKIEAIDMGRRGIHDEGSRTLQERLAGKVRIDFETARRLFTLISVLHWKG
What are the official names of this protein?
UPF0262 protein Rpal_5021.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: DAPF_BLOPB
Sequence: MRFTKMNGLGNDFVIIDAVTQNIHLTSENIRYLSDRFYGVGFDQLLIVEPPYDPAIDFHCRIYNSDGTEVNQCGNGMRCVAQFVCLKKLTNKRNIHISTRANHIILSIMNDNRVSVNMGAPIFDPKLIPFYISQYQKTYILFLPTQIILCGVVSMGNPHCIILVEKIENIQVTSLGSALEDHHCFPERVNVSFMQIINCNNIRLRVYERGVGETQACGTAACAAVAVGIQQGLLYESVNVNLPGGTISVNWKGASNALYMTGSTSYVYDGYINL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_CERS1
Sequence: MIRPALRTDWTVEEARAIHALPFPELMHRAQTLHRAHFDPTAIETASLLSIKTGGCPEDCGYCSQSAHHDTGVKATKLMAEEEVLAAARRAKAAGAQRFCMGAAWRSPKDRDMDQLCDMVRGVADLGLETCMTLGMLSPGQVARLKAAGLDFYNHNIDTSPAYYAQIASTRTMEDRLETVEQVRRGGIKVCCGGILGMGEAEEDRIALLVTLATLPAHPDSVPVNLWNEIEGVPVQGRARAVDPFALVRIVALARILMPASVVRLSAGRTEMSDELQALCFLAGANSIFVGDQLLTTGNPAAWKDRDLLSRLGLHIAPARARPPVAAD
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CYB_TASSH
Sequence: MINIRKTHPLMKIINNTFIDLPTPANISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTATAFSSVTHICRDVNYGWIIRYLHANGASMFFICLYAHIGRGLYYGSYAFQETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTXVEWVWGGFSVDKATLTRFFAFHFILPFIIXALAXVHLLFLHETGSNNPTGIPSBVDKIPFHPYCTIKDILGALLLILTLLTLTLFXPDLLGDPXNYTPANPLXTPXHXXPEXYFLFAYAILRSIPNKLGGVLALLLSILILXFIPMLHTSKQRSMXFXPXSQXXFWXLVADLLTLTWIGGQPVEHPYXXMGQLASILYFLLILVLMPMASXIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ILVA_STAA3
Sequence: MTVKTTVSTKDIDEAFLRLKDIVKETPLQLDHYLSQKYDCKVYLKREDLQWVRSFKLRGAYNAISVLSDEAKSKGITCASAGNHAQGVAYTAKKLNLNAVIFMPVTTPLQKVNQVKFFGNSNVEVVLTGDTFDHCLAEALTYTSEHQMNFIDPFNNVHTISGQGTLAKEMLEQAKSDNVNFDYLFAAIGGGGLISGISTYFKTYSPTTKIIGVEPSGASSMYESVVVNNQVVTLPNIDKFVDGASVARVGDITFEIAKENVDDYVQVDEGAVCSTILDMYSKQAIVAEPAGALSVSALENYKDHIKGKTVVCVISGGNNDINRMKEIEERSLLYEEMKHYFILNFPQRPGALREFVNDVLGPQDDITKFEYLKKSSQNTGTVIIGIQLKDHDDLIQLKQRVNHFDPSNIYINENKMLYSLLI
What is the function of this protein?
Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction.  The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate).  Both intermediates are unstable and short-lived.  The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia.  In the low water environment of the cell, the second step is accelerated by RidA (By similarity).
What are the official names of this protein?
L-threonine dehydratase biosynthetic IlvA, Threonine deaminase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: RDRP_ROTHL
Sequence: MGKYNLILSEYLSFIYNSQSAVQIPIYYSSNSELESRCIEFHSKCLENSKNGLSLKKLFIEYNDVIENATLLSILSYSYDKYNAVERKLAKYARGKPLEADLTVNELDYENNKITSELFPTAEEYTDSLMDPAILTSLSSNLNAVMFWLEKHENDTAEKLKIYKRRLDLFTIVASTVNKYGVPRHNAKYRYEYDVMKDKPYYLVTWANSSIEMLMSVFSHEDYLIARELIVLSYSNRSTLAKLVSSPMSILVALVDINGTFITNEELELEFSNKYVRAIVPDQTFNELNQMLDNMRKAGLVDIPKMIQDWLTDCSIEKFPLMAKIYSWSFHVGFRKQKMLDAALDQLKTEYTEDVDEEMYREYTMLIRDEVVKMLEEPVKHDDHLLQDSELAGLLSMSSASNGESRQLKFGRKTIFSTKKNMHVMDDMANGRYTPGIIPPVNVDKPIPLGRRDVPGRRTRIIFILPYEYFIAQHAVVEKMLIYAKHTREYAEFYSQSNQLLSYGDVTRFLSNNAMVLYTDVSQWDSSQHNTQPFRKGIIMGLDILANMTNDTRVIQTLNLYKQTQINLMNSYVQIPDGNIIKKIQYGAVASGEKQTKAANSIANLALIKTVLSRISNKYSFVTKIIRVDGDDNYAVLQFNTEVTKQMVQDVSNDVRETYARMNAKVKALVSTVGIEIAKRYIAGGKIFFRAGINLLNNEKRGQNTQWDQAAVLYSNYIVNRLRGFETDREFILTKIMQMTSVAITGSLRLFPSERVLTTNSTFKIFDSEDFIIEYGTTDDEVYIQRAFMSLSSQRSGIADEIAASTTFKNYISKLSEQLLFSKNNIVSKGIALTEKAKLNSYAPISLEKRRAQISALLTMLQKPVTFKSSKITINDILRDIKPFFTLREAHLPIQYQKFMPTLPENVQYIIQCIGSRTYQIEDDGSKSAISRLISKYSVYKPSIEELYKVISLHENEIQLYLISLGIPKIDADTYVGSKIYSQDKYRILESYVYNLLSINYGCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHLYAKLEIINYAIKNGSWISLFCNYPKSEMIKLWKKMWNITSLRSPYTNANFFQD
What is the function of this protein?
RNA-directed RNA polymerase that is involved in both transcription and genome replication.  Together with VP3 capping enzyme, forms an enzyme complex positioned near the channels situated at each of the five-fold vertices of the core.  Following infection, the outermost layer of the virus is lost, leaving a double-layered particle (DLP) made up of the core and VP6 shell.  VP1 then catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded through the DLP's channels into the cytoplasm where they function as mRNAs for translation of viral proteins.  One copy of each of the viral (+)RNAs is also recruited during core assembly, together with newly synthesized polymerase complexes and VP2.  The polymerase of these novo-formed particles catalyzes the synthesis of complementary minus-strands leading to dsRNA formation.  To do so, the polymerase specifically recognizes and binds 4 bases 5'-UGUG-3' in the conserved 3'-sequence of plus-strand RNA templates.  VP2 presumably activates the autoinhibited VP1-RNA complex to coordinate packaging and genome replication.  Once dsRNA synthesis is complete, the polymerase switches to the transcriptional mode, thus providing secondary transcription (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, Protein VP1.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging (By similarity).
Protein: RLME_SHEB2
Sequence: MSGIKRTASSNRWMLEHFDDHYVKLAQKMGLRSRAAFKLEEIQQKDQLIRPGMTVVDLGAAPGGWSQVAVKLAGDRGKVIACDILPMDPIVGVDFLQGDFREDKVLQALLTRVGDAKVDVVLSDMAPNMSGSDSVDQPRAMYLVELALDMCHQVLAPNGCFAVKVFQGEGFDEYMKAVKAVFKVVKTRKPDSSRARSREVYLVATGYKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_BORA1
Sequence: MSLMREMLEAGVHFGHQTRYWNPKMAPYIFGHRNKIHIINLEQTVAKYQEATKFVKQLAARGGNILFVGTKRAARELVATEAERCGMPFVDARWLGGMLTNFKTVKSSIKRLKEMEVMVADGSVERLTKKEGLLFQRELDKLNKAIGGIKDMNGLPDALFVIDVGYHKIAVAEARTLGIPVVAVVDTNHSPDGVDYIIPGNDDSARAIALYAKGIADAVLEGREQNLNGLVEEIVEGEEEFVEVQDGQA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: BIOB_SALCH
Sequence: MARHPRWTLSQVTELFGKPLLELLFEAQQIHRQHFDPQQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLDSARKAKNAGSTRFCMGAAWRNPHERDMPYLEKIVQGVKAMGLETCMTLGMLNESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVREAGIKVCSGGIVGLGETVTDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPAEDKDLQLFRKLGLNPQQTRVLAGDNEQQQRLEQTLMTPDTDDYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: TSAC_ALIF1
Sequence: MKNLNQVVDALKQGNVIAYPTEGVFGVGCDPDNEQALLNLLDVKKRPKEKGLILIAASIEQLLPYIDLEQLTEEQVNTIKASWPGPVTWIVPVKTSTLPLVTGQFDSIAVRVTAHPQVKAICNAFGKPITSTSANLSGLEPCRSVTEVEAQLGDTGVVIFQGEVGNRTQPTEIRDAKTGNTLRQG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTLA4_MOUSE
Sequence: MACLGLRRYKAQLQLPSRTWPFVALLTLLFIPVFSEAIQVTQPSVVLASSHGVASFPCEYSPSHNTDEVRVTVLRQTNDQMTEVCATTFTEKNTVGFLDYPFCSGTFNESRVNLTIQGLRAVDTGLYLCKVELMYPPPYFVGMGNGTQIYVIDPEPCPDSDFLLWILVAVSLGLFFYSFLVSAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
What is the function of this protein?
Inhibitory receptor acting as a major negative regulator of T-cell responses.  The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
What are the official names of this protein?
Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalization.
Protein: AZOR_HAEI8
Sequence: MSNVLVLKSSISGNNSQTNQLADYVIEKLQGNNIVVRDLSQQPLPYFDTAAAIAVRGEPKTTEEKQLLALSDKLIEELKNAQTLIIGAPMYNLNVPTQLKSYFDFIARPRVTFQYTANGSEGLLKGKKAIVLCAFGGLYDEENLVTQYMKSILGFIGITDVQFVYAQGIGFGPEAIEKAQASAKNKINEIVAAL
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: PRMA_PROMM
Sequence: MNFAAALRWWRLSLPIADELEESLIWKLTDLGLCRLAVQHAPENSERTLLAWLPSSEWSESDRDQLMANLRPLAEPFGLKLANPTWCEVADEDWSLNWKQDWQPDPVGQRLLILPAWLDLPQEYADRFVVRLDPGSAFGTGSHPSTRLCLEALERNPPLGLRVADLGCGSGVLGFAALAFGARQVLAADTDCQAVCASRANTELNQLDLDRLRVVHGSVEALSAQLEGQTVDLLLCNILAPVIEVLAPSFDQLLSANGRGLLSGLLVKQAPRLQMVLEALGWRVNCLTEQGCWGLLDVSKR
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLS_MALDO
Sequence: MGVESVERERESNEGTIPAEFIRSENEQPGITTVHGKVLEVPIIDFSDPDEEKLIVQITEASSNWGMYQIVNHDIPSEVISKLQAVGKEFFELPQEEKEAYAKPPDSASIEGYGTKLFKEISEGDTTKKGWVDNLFNKIWPPSVVNYQFWPKNPPSYREANEEYAKHLHNVVEKLFRLLSLGLGLEGQELKKAAGGDNLEYLLKINYYPPCPRPDLALGVVAHTDMSTVTILVPNDVQGLQACKDGRWYDVKYIPNALVIHIGDQMEIMSNGKYTSVLHRTTVNKDKTRISWPVFLEPPADHVVGPHPQLVNAVNQPKYKTKKYGDYVYCKINKLPQ
What is the function of this protein?
Catalyzes the formation of flavonols from dihydroflavonols.  It can act on dihydrokaempferol to produce kaempferol, on dihydroquercetin to produce quercitin and on dihydromyricetin to produce myricetin (By similarity).
What are the official names of this protein?
Flavonol synthase/flavanone 3-hydroxylase, FLS.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCJF_SALTY
Sequence: MSEPLKPRIDFAEPLKEEPTSAFKAQQTFSEAESRTFAPAAIDERPEDEGAAEAAVDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVALGGCAAGALIVGAGVGSVVTEWRRLWRLRQRAHERDEARELLHSHSVGKGRAFCEKLAQQAGIDQSHPALQRWYAAIHETQNDREIVGLYANLVQPVLDAQARREISRFAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFRLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDNDKPRLGDFRRQLIGQLKETLQKSKSSPEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AUX28_SOYBN
Sequence: MGFEETELRLGLPGNGGTEEVLIRKRGFSETETGHEDESATTVDLMLNLSSKEAATTAAAAADPTDKHKTLPKEKTLLPADPAKPPAKTQVVGWPPVRSFRKNMLAVQKSVGEESEKNSSPNASFVKVSMDGAPYLRKVDLKMYKSYRELSDSLGKMFSSFTFGNCESQGMKDFMNESKLNDLLNSSDYVPTYEDKDGDWMLVGDVPWEMFVESCKRLRIMKGKEAIGLGLAPRAMAKCKNRS
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression (By similarity).
What are the official names of this protein?
Auxin-induced protein AUX28.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: WUHO_DROPE
Sequence: MATIFFAEPELVIGHGRKVLFLNPGDLQIFKEIELPPDLTTCGLKTVEPVPAPGHPASSSKQQPAALKEATGSVKVEVSIQNVTYSPDRQLLALTTAGQKAVLLYKSRPENAQLLSIRPLARASSAPKVLQRWQLPFWSLTKREIAINTSVLRWMPRHVCFLGHLSIVYDVLWSEDQQYIITCDRDDKIRVTNYPATFDIHSYCLGHKEFVSGLAMLTEQHIISASGDKTLRVWNYTCGKELLLHELPAPAVRMLVRQLEPEKTYEVAVLFYDYVDAIGVYRLEQTTTESWSITSTQLVRAEAGTWNICNFALTDDRIYVTGAENERLTLRVYDSRNGERASGLPEGWLKMVLDNLDVAAFMPEDLSVWFKKRFDNVSDYLERKKRRIEEQKQQKCG
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.  Required during gametogenesis.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localized to the nuclei of nurse cells, follicle cells and oocytes at early stages, from germarium to stage 4 egg chambers. Also present in the nuclei of spermatocytes and in the apical cells of the testes.
Protein: MIP_CAVPO
Sequence: MWELRSASFWRAIFAEFFATLFYVFFGLGASLRWAPGPLHVLQVALAFGLALAXLVQTVGHISGAHVNPAVTFXFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAVRGNLALNTLHAGVSVXQATTVEIFLTLQFVLCIFATYDERRNGRLGSVALAVGFSLTLGHLFGMYYTGAGMNPARSFAPAILTRNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSVSERLSILKGTRPSDNNGQPEGTGEPVELKTQAL
What is the function of this protein?
Water channel.  Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased.  May be responsible for regulating the osmolarity of the lens.  Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.  Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity).
What are the official names of this protein?
Lens fiber major intrinsic protein, Aquaporin-0.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: HTPG_CLOPE
Sequence: MEKREFKAESKRLLDIVINSIYTNREIFLRELISNASDAIDKVYYKTLGDSSLTFNKDDYYIKIKPNKEERTLTISDKGIGMTEKELDENLGVIAKSGSLQFKKENEIKDGFDIIGQFGVGFYSGFLVADKITVITKAFGADKAYKWESDGVDGYTISEAEKDSFGTDIILHLKANDEDENYDEFLEEYKLKSLIKKYSDFIRYPIKLDVTKSRVKEGTENEHEEYVEEETVNSMVPLWRRNKNELTDDDYNNFYVEKRFGFDKPLRHMHISVDGMISYNSILYIPENIPYDYYTKEYEKGLELYSNGVLIMEKCSELLPDYFGFVKGIVDSQDLSLNISREMLQHDRQLSRIAKNIKTKIKNELESMMKNDRESYEKFYKSFGRQLKYGVYDDFGMNKDELKDLLMFYSSKEKKMVSLAEYVERMAEDQKYIYYAVGESNERIEKMPQTEMVLDKGYEILYFTEDVDEFAIKMLMNYKEKEFKSVSSGDLGIESEEENKKENEENKGIFEAMKEALGEKISAVKASSRLKNYPVCLSSEGEVSIEMEKILSAMPNNQGVKAQKVLEVNTNHEVFNSLKDALENDKDKFNLYTKLLYNQALLVEGLSIENPVDFTNDICKLMK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS41_RUEST
Sequence: MMIYPTMELLDGRCVTLDKGNLDAPMIWHVDPVETAKGFAEAGAEWMHLTDFNALQGDSSNQDLVEELIRTAGLPIQLGGGIRSREQAEFWIEKGVGRVVIGTMAAYDPAAVAELAKYYPDQVVLAVDVWQGQVMTEGWRKSGAWTPEAFVKAFGNAPFAGILVTDIDSDMSDLDAQLGLISGLAEQAHSPVIASGVVRSKDDISRLKYLPNISGALVGRALFNKTITLEEAMETAQPNPEPVAEFL
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4C_CHAGL
Sequence: MISDFPLLTFITLFPISAGLLIPFLDKKGNQLVRWYTLIICLIDFVITSYIFIYKYDLNIDTLQLIDDYAWVGPIEFHWKLGVDGLSMPLILLTSFITTLATLSAWPITRNSRLFYFLMLAMYSGQLGVFLSQDILLFFLMWELELIPIYLLLSLWGGKRRLYAATKFILYTAVGSIFILMAGLTMAFYNSNVPLLDFQSLANKQYPLALEIVLYLGFLIAFAVKLPAFPLHTWLPDTHGEAHYSTCMLLAGILIKMGGYGLIRINMELLPNAHVIFSPWIALIGGIQIIYGALTSLGQRNLKRRIAYSSISHMGFVMIGISSFTDLGLSGAMMQMVSHGLIGAGLFFLAGTSYDRIRTLFLDQMGGISTTMPKIFAMFTTCALASLALPGMSGFVAELMVFLGFLKSNAYSFDFIALITFLEAVGIILTPIYLLSMLRQMFYGYRKLKLTNTLLLDASPREIFIMSCLFLPIIGIGIYPNLTIPLWNTKVEAIEQLNVFKSVGFK
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: BOPA_BURP1
Sequence: MINVDAFVASARSGARVVVGGDARGPVVSAARLGMKERLFAFLAHVPLLKHCDAVRRYAEQVRMENRRSLEVFVLALSKRYGPEGAKAAFDYGARRDGAPLDQRRVRNMVSIAEHFHGTGDAKPLARQMVFRSWECRGLDHPGHASLTIKNQADADAGRHVYEHVSWWPNQRLGSKEHFDRIEPKTLDGYRIDKRSEISSATEQRLREGDAARRKILADGFKYANQDERHDARFFPRAGQKLDKDAEWGLSARKVYFPAIGFNHDRRDTDRPRAFVLFGLNEAAMLRDARTVKEGAKSGELMYQMISKKENCASMALRVLRAGGAEHFVPYTAAWISEDPNHAHAYALAVQARIDALNQRRADVERRCERLRDSASVRQAWRAFSEAGGASASPLAEDAGRGRASAHMRQARLDEHAREVERIGAYFAELSAGRSGKHRDRADAALADAMKRCAPSARDDVAALTRKASVLVETLGRHLDAPPPSDSSALRRLAAHAMIGRIEAFMAAAIAA
What is the function of this protein?
Plays a role in mediating bacterial evasion from the host autophagic pathway.
What are the official names of this protein?
Effector protein BopA.
What is the protein family that this protein belongs to?
Belongs to the BopA/IcsB family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the bsa type III secretion system.
Protein: NDHH_MORIN
Sequence: MNIPAPRKDLMIVNMGPHHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITINGPELLGNIQVPKRASYIRAIMLELSRIASHLLWLGPFLADIGAQTPFFYIFRERELVYDLFEAATGMRMMHNFFRIGGVAADLPHGWIDKCLDFCDYFLIGVTEYQKLITRNPIFLERVEGVGVIGREEVINWGLSGPMLRASGIQWDLRKVDHYECYDEFDWEVQWQKEGDSLARYLVRIGEMTESIKIIQQALEGIPGGPYENLEIRYFDRERNPEWNDFDYRFISKKPSPTFELPKQELYVRVEAPKGELGIFLIGDQSGFPWRWKIRPPGFINLQILPQLVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.