PharMolix/UniProtQA huggingface dataset:
Protein: PDSA_ARTGP
Sequence: MPVADIEMVTGSAGHVDSKAASEYGTDLRRWRLKVHEGRHMWEYVDEDVAQTQQQTFAENYWLGQEYELPKMSTPIFAQDALDNGWAFFKRLQTQDGHWGCHDDGPLFVTSGIVISSYICGITLPDAMKNEMIRYLLNFVNEDGGWGLWINSPSTVFGTTMNYTMLRILGVPSTHPALLDARDTLLKMGSARALPTWGKFWMCALGAYEWDGMIPLAPEPLLAPGFLPLNPGNWWVHTRNVFVSMSYLFGHRFSAPMTPLIQELREELYDMPYHKIDWFAQQTNISDYDRLHPPTMLQKGLANALCYYEYVKVPYLRRKALDEALFQVEMEVHNTSYLCIAPVSFASNMLVMFHAHGANSHWVKGMADRIIDPMWMCREGMAASGTNGTSVWDTALTVQAALDGGLAQRPENHNTMLEALKFIEVSQITENPLGVSQGYRQPTKGAWPFSTRDQAYAVSDTTAVTVRAVIQLQALKSMPKLVSDERLAEAVDLIIGMENKCDGYSAFEPLRGPKALELLNITELYDNVMTESLYPECTSSVLLCLDTFTKAYPHHRPVEIQSIMARCARYLIKAQFPCGGWLASWGVCFTYATMFALQGLETVGLRESNSETCRNACSFLLQYQNDDGGWGEDLISIREKRYIQDPAGSQVTCTAYALMGLISAHCSNRDALRRGIRWLMRAQQATGEWLPGSLEGIFACPGGMRYPNYKFHFTLSAIGRYIERYGDEALYLKEQ
What is the function of this protein?
Protostadienol synthase which cyclizes (3S)-oxidosqualene to (17Z)-protosta-17(20),24-dien-3-beta-ol (protostadienol), the biosynthetic precursor of helvolic acid, a secondary metabolite which promotes virulence.
What are the official names of this protein?
Protostadienol synthase A.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: MTLD_ECOSM
Sequence: MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGLVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHFRSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RS2_PSEA6
Sequence: MANVSMRDMLQAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPLFNNALNYIGSVASKKGKILFVGTKRAASDSVRDAAVKCDQFYVNKRWLGGMLTNWKTVRQSIKRLKDLEQQSQDGTFDKITKKEVLMLQREMAKLENSLGGIKNMGGLPDCLFVVDADHEHIAITEARNLGIPVVSIVDTNSNPDGVDYIIPGNDDAIRAVQLYLNSAADAVIEGREKNIEVQAEEGEFVEAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: METK_VIBVU
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEITTSAWVDIEELTRETVREIGYVHSDMGFDANSCAVLNTIGKQSPDINQGVDKADPKEQGAGDQGIMFGYACNETEVLMPAPITYAHRLMERQAKVRKDGTLPWLRPDAKSQVTFQYEQGKIVGIDAVVLSTQHCDSISTPDLREAVMEEIIKPVLPSEWLNKETKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGMADRCEIQLSYAIGVADPTSIMVETFGTEKVSHDIIIEAVRQFFDLRPYGLQEMLNLLQPIYKKTAAYGHFGREEFPWEATDKAALLREFAGIK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCHB_ECOL6
Sequence: MREITESQLRYISGAGGAPATSANAAGAAAIVGALAGIPGGPLGVVVGAVSAGLTTAIGSTVGSGSASSSAGGGS
What is the function of this protein?
Bactericidal antibiotic.  Active on bacteria phylogenetically related to the producing strain (By similarity).
What are the official names of this protein?
Microcin H47, MccH47.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Single-pass membrane protein. Note=Probably through the MchEF ABC transporter system.
Protein: MKRN2_MOUSE
Sequence: MSTKQVTCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGYCAYGARCRYDHTKPPAAAGGAVGPAPNPSPSSGLHSPHPSPDIATSVMRTHSNEPGKREKKTLVLRDRNLTGLAEDKTPPSKVNNPGGCSDPQTSPEMKPHSYLDAIRTGLDDLEASSSYSNEPQLCPYAAAGECRFGDACVYLHGDMCEICRLQVLHPFDPEQRKAHEKMCMSTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCSHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSEGTVRFFNSVRLWDFIENRETRQVPSTDDVDVTELGDLFMHLSGVESSEP
What is the function of this protein?
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (PubMed:28378844).  Promotes the polyubiquitination and proteasome-dependent degradation of RELA/p65, thereby suppressing RELA-mediated NF-kappa-B transactivation and negatively regulating inflammatory responses (PubMed:28378844).  Plays a role in the regulation of spermiation and in male fertility (PubMed:28008940).
What are the official names of this protein?
E3 ubiquitin-protein ligase makorin-2, RING-type E3 ubiquitin transferase makorin-2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CSPL6_POPTR
Sequence: MAKIKKIFTNFLRLLALAATVVAIVFMVTSHDSAQVLNLTFTVKYSNTPVFKYFVIAEAIAGGYIVISILLSFKSLFWRLLVILDMVTAVLLTSSISAALAIAQVGKKGNTHAGWLPVCEQVPDFCDQVTIALIAGFAAAIIYFVLLLCSLYVVLSPIFVVTP
What are the official names of this protein?
CASP-like protein 1C3, PtCASPL1C3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DUS18_BOVIN
Sequence: MTASPCAFPVQFRQPSVSGLSQITSSLYISSGVAANNRLMLSSNRISTVINVSVEVVNALYEDIHYVQVPVADTPTSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNNGFWEQLIHYEFQLFGRNTVHMVSSPVGMIPDIYEKEVRQMIPL
What is the function of this protein?
Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine.  In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP).
What are the official names of this protein?
Dual specificity protein phosphatase 18.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Translocates to cytoplasm in response to apoptotic stimuli such as staurosporine treatment.
Protein: LUXC_ALIFS
Sequence: MNKCIPMIINGMIQDFDNYAYKEVKLNNDNRVKLSVITESSVSKTLNIKDRINLNLNQIVNFLYTVGQRWKSEEYNRRRTYIRELKTYLGYSDEMARLEANWIAMLLCSKSALYDIVNYDLGSIHVLDEWLPRGDCYVKAQPKGVSVHLLAGNVPLSGVTSILRAILTKNECIIKTSSSDPFTANALVSSFIDVNADHPITKSMSVMYWPHDEDMTLSQRIMNHADVVIAWGGDEAIKWAVKYSPPHVDILKFGPKKSLSIIEAPKDIEAAAMGVAHDICFYDQQACFSTQDVYYIGDNLPLFLNELEKQLDRYAKILPKGSNSFDEKAAFTLTEKESLFAGYEVRKGDKQAWLIVVSPTNSFGNQPLSRSVYVHQVSDIKEIIPFVNKNRTQTVSIYPWEASLKYRDKLARSGVERIVESGMNNIFRVGGAHDSLSPLQYLVRFVSHERPFNYTTKDVAVEIEQTRYLEEDKFLVFVP
What is the function of this protein?
LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.
What are the official names of this protein?
Long-chain acyl-protein thioester reductase, Acyl-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the LuxC family.
Protein: RS20_BIFLD
Sequence: MANIKSQKKRVLTNEKAHLRNVAVKSGLKTAIRATREAIAAGDKAAAEAAYKVAAQKLDKAAGAGVIHKNQAANRKSGLAVAINAL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RLUD_PASMU
Sequence: MAQITLSAEIQLSQLGQRLDQALAELFPDYSRSRLKTWIEQNLVHVNGDVVNVPRAKVYGGEQIEIVVEIDDDTRFEPENLPLNIVYEDDDILVINKPKDFVVHPGAGNASGTVLNALLYHYPAIAEVPRAGIVHRLDKDTTGLMVIAKTIPAQTKLVRDLQKRKITREYEAIACGIMTKGGMVDQPMARHPTKRTHMAVHPMGKPAVTHYRIMERFRNYTRLRLRLETGRTHQIRVHMAHIAHPLLGDQTYGGRPRPPKNASEELMQTLRDFKRQALHAIMLRLAHPITGELMEWHAPLPTDFVELVEALKADYQLHQDDLDY
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase D, 23S rRNA pseudouridine(1911/1915/1917) synthase, rRNA pseudouridylate synthase D, rRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: TRPB_BUCMH
Sequence: MTLLNSYFGDFGGMYVPQILMPALYQLEEEFIFSLKSSKFKIELSNLLENYAGRPTPLTLCRNLTKGTKTKIYLKREDLLHGGAHKTNQVLGQALLAKKMKKKEIIAETGAGQHGVAAAFSCALLNLKCRIYMGLKDINRQQQNVFRMKLMGAEVIPVKTGSGTLKDACNEALRDWSENYINAHYMLGTAAGPHPYPTIVKEFQSIIGKETKRQIVREENCLPNAVIACVGGGSNAIGIFSSFISDNSVSLIGVEPGGKGIHTNKHGAPLTHGETGIFFGMKTKIMQTEEGQIKESWSISAGLDFPAVGPEHAWLYSTKRAQYVSITDHEAVNAFRCLSKSEGIIPALESSHALAYALKLMNNHPQKNQILIVNISGRGDKDIETVKNFLKM
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: L1137_LEGPH
Sequence: MIQRGFTMQERREKQGNNSPYLLTPYEMANLVFKTGAISFTVSAGTQPFQYLLNKLQFSQSGTPSGLSGGLFRGMYRGFLPYAIAGQKRGAVAVTHKQTNKVTEEEEFEAPFRQRWWGTIFFSQADLLVSNGLSGKARLQNVGVINAENFKWSLSNFWKLTSVNWGSRSFAGGVNFALIGFAGDYVSSFYKFDKDLYNKILGGATSGVIATLFTTAPNAYADSKLLQTKVAENNRLITVSPYTMFGQMKSHVKAVGLKEAFMTFFKVSYLQQVAVRAPQAAITFALIFGMDEYMGPQPLKKVWPGRVEELESENPSPSPTKK
What is the function of this protein?
Serine protease effector that inhibits host cell autophagy by targeting SNX17 (PubMed:28504273).  Localizes to the host endoplasmic reticulum-mitochondria contact site and catalyzes degradation of host SNX17, thereby impairing endoplasmic reticulum-mitochondria communication, leading to inhibit autophagy as well as staurosporine-induced apoptosis (PubMed:28504273).
What are the official names of this protein?
Serine protease Lpg1137.
What are the subcellular locations of this protein?
Secreted. Host mitochondrion membrane. Note=Localizes to the host mitochondria-associated endoplasmic reticulum membrane (MAM).
Protein: GPDA_SULSY
Sequence: MNLGVIGAGSWGTALAQILSVNFENVFIWDIDKEVLDSVKNSNINVKYHPDIKLNTNIKPIYDLQELINISDILIVVIPTQYIRQTLSKVKIENKPVISASKGIEIESLKLVSDIMEESLGIDRKYIFALSGPSFAKEVIKGLPTAVVLAGNTEIGNKLLSYLNTKTFRVYLSDDLVGAEVGGAIKNVIAIAAGISDGLGFGSNARASLITRGLYEISKIVKIYGGNPQTVYGLSGLGDLVLTATGELSRNRTFGMLIGQGYSVEEALKKVGQVVEGYTTVKAVYDIKNKYNIELPISYQVYRVLYENLNPKDAAMELMNRGYKFEFMEENK
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2CS_RHIDP
Sequence: GLLEFNKMIKFETRKNAIPFYAFYGCYCGWGGRRRPKDA
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 CS24a, PLA2, RsPLA2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYS_LIMRD
Sequence: MLDIKKIRQEPDFYKEKLATRGVKPEEIDEVIALDKKRRELLQQTETMKAQRNEASKKIGEAKRNGESADAAIKETRELGDKIKELDTEVEANDAELHDKMAHLPNVPHDGVPVSLTEDGAVELRKVGKVRDFDFEPKHHWDIGENLGILDFDRAGKVSGARFVYYLGLGAQLERAVYNFMLDEHMKEGYTEVLPPYIVNADSMYGTGQFPKFKEGVYQVNGEDMTLIPTAEVPLTNYYRGEVIPTEELPVYVTALTPSFRSEAGAAGRDTRGLIRMHQFNKVEMVKYTKPENSWDELEKMTANAENILKKLNLPYHVITLTTGDMSFTASETHDLELWMPAQNKYREVSSCSNCLDFQARRMHTQYRDENGKLQYVHTLNGSGLAVGRTVAAILENYQNADGSVTIPEVLVPYMHGVTKITKENAVPFRNKVNK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHSD_RICTY
Sequence: MIYDFKAEIIKSKSSSSSKSGAHHWLLQRVTGVVLALCSFWLIYFMFTNKNNDINIIMWEFKKPFNIVILLITVTISLYHSVLGMRVVIEDYINCHKLRNTLIIIVKLFCILTIVAFIVAIFYSE
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase hydrophobic membrane anchor subunit.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FPG_EXIS2
Sequence: MPELPEVETVRRSLERTVSGKTISSVKVFHPKMIRGMEVAPFVDALKQERIERVERRGKFLLFTFDRFYLVSHLRMEGKYFPYPQAIEKDKHTHVIFRFTDGSELHYNDVRKFGTMELREKETAMSVPPLAQLEREPFDPTFTAEVLAENLIRKKRSPIKTSLLDQSIFLGLGNIYVDETLFAARVHPLTKAGALTLDDISRIHAAGVDVLAKAVESGGSTIRSYVSPTGKGEFQLQLAVYGQTGAPCPRCGTAIEKIKVGGRGTHFCPTCQQVAL
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: NIFJ_NOSS1
Sequence: MSQTFATIDGNEAVARVAYKLNEVIAIYPITPSSAMGEWADAWMAEGRPNLWGTVPSVVQMQSEGGAAGAVHGALQTGSLSTTFTASQGLLLMIPNLYKIGGELTSMVVHVAARSLATHALSIFGDHSDVMAARGTGFAMLCSASVQESHDFALIAHAATLDTRVSFLHFFDGFRTSHEVQKVELLADDDVRSLINEDKIFAHRARALTPDSPLLRGTAQNPDVFFQAREGANPYYNACPAIVQGIMDKFGERTGRYYQIYEYHGASDADRLIIIMGSGCETVHETVDYLNARGEKVGVLKVRLFRPWDVERFVQALPHSVQAIAVLDRTKEPGSAGEPLYQDVVTAIHEGWVNKNNSPVPSPQSPVPKIIGGRYGLSSKEFTPAMVKAVFDNLAQATPKNHFTIGINDDVTHTSLEYDPSFSTEPDNVVRAMFYGLGSDGTVGANKNSIKIIGEGTDNYAQGYFVYDSKKSGSMTVSHLRFGSQPIRSTYLIDQANFIGCHHWGFLERIEVLNAAAHGATILLNSPYNAATVWENLPLKVRLQILDKQLKLYVINANQVARDSGMGGRINTIMQVCFFALAGVLPEVQAIAKIKQAIEKTYGKKGVEVVRMNLQAVDQTLENLHEVKIPIEEKGKWIDEEALLSNQSPFSTSAPKFVRDVLGKIMVWQGDDLPVSTLPPDGTFPTGTAKWEKRNVAQEIPVWDTDICVQCSKCVMVCPHAAIRAKVYQPSELENAPPTFKSVDAKDRDFANQKFTIQVAPEDCTGCAICVNVCPAKNKSEPSLKAINMANQLPLREQERDNWDFFLNLPNPDRRNLKLNQIRQQQLQEPLFEFSGACAGCGETPYVKLLTQLFGDRSVIANATGCSSIYGGNLPTTPWTKNNDGRGPAWSNSLFEDNAEFGFGYRLSLDKQAEFAAELLQQFSTEVGDNLVDSILKAPQKTEADIWEQRQRIELLKQQLDKIPTFDPNLKSKIQNLKSLADYLVKKSVWIIGGDGWAYDIDFGGIDHVIASGRNVNILVMDTEVYSNTGGQSSKATPKAAVAKFAASGKPAQKKDMGLMAMNYGNVYVASVALGAKDDQTLKAFLEAEAFDGPSIIIAYSHCIAHGINMTTGMNQQKALVESGRWLLYRYNPLLQEQGKNPLQLDMRSPTQSVEQSMYQENRFKMLTKSKPEVAKQLLEQAQAEVDARWQMYQYLASR
What is the function of this protein?
Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase.
What are the official names of this protein?
Pyruvate-flavodoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
Protein: SC242_SACU7
Sequence: MSHHKKRVYPQAQAQYGQSATPLQQPAQLVPPQDPAAAGMSYAQMGMPPQGAAAPMGQPQFLTPAQEQLHQQIDQAATSMNDMHLHNVPLVDPNAYMQQQVPAQAGMPFQQQQQPLPAQVYGQPSAAMGQNMRPMNQLYPIDLLTELPPPITDLTLPPPPLVIPPEKMLVPSEVSNASPDYIRSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCRRCRSYMNPFITFIEQGRRWRCNFCRLANDVPMQMDQTDPNDPKSRYDRNEIKCAVMEYMAPKEYTLRQPPPATYCFLVDVSQASIKSGLLATTINTLLQNLDSIPNHDERTRISILCVDNAIHYFKIPLDSDNNEGSTDQINMMDIADLEEPFLPRPNSMVVSLKACRQNIESLLTKIPQIFQSNLITSFALGPALKSAYHLIGGVGGKIIVVSGTLPNLGIGKLQRRNESGVVNTSKETAQLLSCQDSFYKNFTIDCSKVQITVDLFLASEDYMDVASLSNLSRFTAGQTHFYPGFSGKNPNDIVKFSTEFAKHISMDLCMETVMRARGSTGLRMSRFYGHFFNRSSDLCAFSTMPRDQSYLFEVNVDESIMTEYCYIQVAVLLSLNNSQRRIRIITLAMPTTESLAEVYASADQLAIASFYNSKAVEKALNSSLDEARVLINKSVQDILATYKKEIVVSNTAGGAPLRLCANLRMFPLLMHSLTKHMAFRSGIVPSDHRASALNILESLPLKYLIKNIYPDVYSLHDMADEAGLPLQTEDGETTATVVLPQPLNATSSLFERYGLYLIDNGNELFLWMGGDAVPALVFDVFGTQDIFDIPIGKQEIPVVENSEFNQRVRNIINQLRNHDDIITYQSLYIVRGASLSEPVNHASAREVATLRLWASSTLVEDKILNNESYREFLQIMKARISK
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC24-2.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YGI4_BACC1
Sequence: MIVTTTSTIQGKEIIEYIDIVNGEAIMGANIVRDLFASVRDVVGGRAGAYESKLKEARDIAMEEMKTFARQKNANAIVGIDVDYEVVREGMLMVAVSGTAVRI
What are the official names of this protein?
UPF0145 protein BCE_5284.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: TRPA_THEVB
Sequence: MIVPKISERFEHCRARQRCALIPFLTAGDPDLETTVAALKILDDHGADLIELGMPYSDPLADGPVIQAAATRALQRGTRLEAVLEMTTDLHQQLTAPLILFSYYNPIYHRGVSSFLKAVAQAGIKGLVIPDLPLEEAEPVLAETANLGLELTLLIAPTTSPERMRAIATASQGFIYLVSTTGVTGMRQEMASRVQELLHTLRQITPKPIGVGFGIASPEHARQVRDWGADAAIVGSAFVKRLAEPDQGLAAVAEFCQSLRTALDTP
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: LMP1_EBVA8
Sequence: MEHDLERGPPGPRRPPRGPPLSSSLGLALLLLLLALLFWLYIVMSDWTGGALLVLYSFALILIIIILIIFIFRRDLLCPLGALCLLLLMITLLLIALWNLHGQALYLGIVLFIFGCLLVLGLWIYLLEILWRLGATIWQLLAFFLAFFLDLILLIIALYLQQNWWTLLVDLLWLLLFLAILIWMYYHGQRHSDEHHHDDSLPHPQQATDDSGHESDSNSNEGRHHLLVTGAGDGPPLCSQNLGAPGGGPDNGPQDPDNTDDNGPQDPDNTDDNGPQDPDNTDDNGPQDPDNTADNGPHDPLPHNPSDSAGNDGGPPNLTEEVENKGGDRGPPSMTDGGGGDPHLPTLLLGTSGSGGDDDDPHGPVQLSYYD
What is the function of this protein?
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation.  Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family.  LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells.  Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins.  For example, induces the sumoylation of host IRF7 thereby limiting its transcriptional activity and modulating the activation of innate immune responses.  Inhibits also host IFN-alpha-stimulated STAT2 nuclear translocation and interferon-stimulated response element transcriptional activity by interacting with and inhibiting host TYK2.  Induces SUMO expression during viral latency thereby dysregulating the host sumoylation processes.
What are the official names of this protein?
Latent membrane protein 1, LMP-1, Protein p63.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae LMP-1 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein.
Protein: PPIG_MOUSE
Sequence: MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSDSDSSSDSQSSSESSDSESASEEKSRKRKKKHRKNSRKHKKEKKKRKKSKKSPSSESEAENVDAQPQSTVRPEEIPPIPENRFLMRKSPPKADDKERKNRERERERECNPPNSQPASYQRRFLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKEKKITDHRHMSESPNRKVEKEKKAKDHKSESKERDIRRNSEKDDKYNKNKVKKRGKSKSRSKSKERSKSKERDSKHSRHEDKRVRSRSKERDHETTKEKEKPLDPKGKDQERSRSKENSKQVESKSNEHDHSKSKEKDRRAQSRSRERDLTKSKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRDRRTPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRSQESKSSHRKENSEGEKRTYSKSRDHNSSSNNREKKADREQSPVSKTKQSSQDNEVKSSTLKNQEDEKTRSPVEKENQKSKGQENDHVHDKNKKCDHESSPGTDEDKSG
What is the function of this protein?
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.  May be implicated in the folding, transport, and assembly of proteins.  May play an important role in the regulation of pre-mRNA splicing.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase G, PPIase G, Peptidyl-prolyl isomerase G, Cyclophilin G, Rotamase G.
What are the subcellular locations of this protein?
Nucleus matrix. Nucleus speckle. Note=Colocalizes with splicing factors at nuclear speckles.
Protein: HCS1_SCHPO
Sequence: MSSSNEQICLDEDWIQKFGDREIEFVDEAQKSEVDETEKSIKRFPLSVLQRKGLALINLRIGVVKTGFGGKTIIDFEKDPAFSNGEELPANSFSPGDVVSIRQDFQSSKKKRPNETDISVEGVVTRVHERHISVALKSEEDIPSSVTRLSVVKLVNRVTYERMRHTMLEFKRSIPEYRNSLFYTLIGRKKADVSIDQKLIGDIKYFNKELNASQKKAVKFSIAVKELSLIHGPPGTGKTHTLVEIIQQLVLRNKRILVCGASNLAVDNIVDRLSSSGIPMVRLGHPARLLPSILDHSLDVLSRTGDNGDVIRGISEDIDVCLSKITKTKNGRERREIYKNIRELRKDYRKYEAKTVANIVSASKVVFCTLHGAGSRQLKGQRFDAVIIDEASQALEPQCWIPLLGMNKVILAGDHMQLSPNVQSKRPYISMFERLVKSQGDLVKCFLNIQYRMHELISKFPSDTFYDSKLVPAEEVKKRLLMDLENVEETELTDSPIYFYDTLGNYQEDDRSEDMQNFYQDSKSNHWEAQIVSYHISGLLEAGLEAKDIAVVTPYNAQVALIRQLLKEKGIEVEMGSVDKVQGREKEAIIFSLVRSNDVREVGFLAEKRRLNVAITRPKRHLCVIGDSNTVKWASEFFHQWVDFLEENAIVMDIDATMFE
What is the function of this protein?
DNA polymerase alpha-associated DNA helicase which may be involved in DNA replication.
What are the official names of this protein?
DNA polymerase alpha-associated DNA helicase A.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y6503_SACS2
Sequence: MSMPYDNEAKIKQAVILLQKIVNDTSVPRNIRRAATDAIRNLQDLGLSPAVRAANAIGILEDISQDPNMPTHARISIWNVVSILETVKD
What are the official names of this protein?
UPF0147 protein SSO6503.
What is the protein family that this protein belongs to?
Belongs to the UPF0147 family.
Protein: KAX32_LEIHE
Sequence: GVPINVSCTGSPQCIKPCKDAGMRFGKCMNRKCHCTPK
What is the function of this protein?
Potent inhibitor of the Shaker potassium channels and its mammalian homologs (Kv1. 1/KCNA1, Kv1. 3/KCNA3, Kv1. 6/KCNA6) (Ki<1 nM for all channels) (PubMed:8204618, PubMed:20007782).  Also blocks Kv1. 2/KCNA2 (IC(50)=26. 8 nM) (PubMed:8204618, PubMed:20007782).  It also shows a weak interaction with nicotinic acetylcholine receptors (nAChR), suggesting it may weakly inhibit it (PubMed:31276191).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 3.2, Agitoxin-2, AgTx-2, AgTx2.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS17_EHRRG
Sequence: MKERMRSRMSKQVLTGVVVGAKCDKTIKVMVSRMVSHKMYKKIVKKRKNYVVHDEYNRYKCGDVVQIREHIPISATKRWVVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: YSO3_ACIAM
Sequence: MVDYLALLSSQNPYDRLDGWFKIDWLIQNNIVTKEKLIEMKDKFLDLLSYNDDTVKLHAWRMVPQLINKGIITVKDVKKYDFLSLLYDSEAWLLVKDLVNSGVIDIESVKKEKEKYIALLKGNELDRIASWSLILDIVNLGIIDKNDVENNKKYLLELFNFPAYDIRFNLLFLVAELISKGVLSPKELEPYEKKIEEIVKDKDFNQFVKIYEKDPRELESIGIHVFNS
What are the official names of this protein?
Uncharacterized protein in sor 5'region, ORF3.