PharMolix/UniProtQA huggingface dataset:
Protein: NDHI_STAPU
Sequence: MINGLKNYSQDALRAARYIGQGFFVTLDHMNRTPITIQYPYEKLIPSERFRGRIHFEFDKCIACEVCVRVCPINLPVVDWEFQKSMKKKQLKSYSIDFGVCIFCGNCVEFCPTNCLSMTEEYELSSYDRHELNYDQVALGRLPNPASKDPLVHPILGLGYLQKKLLTQSTESKTITNFDKS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MTNN_SHEPW
Sequence: MKIGIIGAMEPEVAHLVESMENSTSTTIAGIEFVAGQLAGQEVIVTRSGIGKVTASIATTLLIEKYAPDAIINTGSAGGFADDLAIGDIVISSEVRHHDVDVTAFGYEIGQMAQQPAAFLPDAKLVAAAQKAVASLGEVKAIEGLICTGDSFICDPVRTKTMLENFPTMAACEMEAAAIAQVCHQFAVPFVVIRSLSDNANDDSAVDFDEYIIKAGLHSALMVIALIKQL
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: RL9_CUTAK
Sequence: MKLILTAPVAKLGVPGDIVEVKDGYGRNYLLPQNYAIKWTRGAEAQIKDITRARKAKEIKSKEEAEQIRSQLEHLVVQVTVQVGENGRLFGAVTPGDIALAVRKAGGPALEKRSIEITKPIKTIGKHTVGVKLHDAIKGHVTVETVPAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: AP4M_DICDI
Sequence: MFSQFFILNNKGETIIFKDYRFDISKDSNEIFFKHVQSMKSEITPAFNIDGINYLYIKKREMYFVFTTRLLVSPSLGFELLNRASKIIQDYTASLTEEAIRLNFILIYELLDELMDYGVPQSTGTETLKAFVFTPPKQIKSKQLESDSIIDNFLKATNKISVPPKQGVKPIHSGSKNSSSGGSSLSTNTVSKVVNNIVDSISGAATNLHNSTSGGGSGSGVTDADGDNEIYIDLCERLTVLYSSNGTILRNEITGKIQMKSYLRGNPALSLGLSPEFTFKTIANRDESNENEIDNNNIGGVSNLSAPSSNTTSFIVDDCSFHECAGSGFQPNNTINFKPPQGDFTLLKYRISNNNYTPFLVKTNLESTIRNRFDLVVTIRSNFSNKVVPNFIFVSIPVPKSTKSLTHSLDYGSQNQKVEYKQSTQAGNLVFWSIKKLRGGMETILRIQIHVDGATSSSSNNNQQQQQPQIDVGSTLRKEIGPIGLEFSIPQFSCSTLQIKFLKMLGSNISPIRWIRYITDSKSFVSRINN
What is the function of this protein?
Probable component of an adaptor protein complex.  Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection.  They control the vesicular transport of proteins in different trafficking pathways.
What are the official names of this protein?
AP-4 complex subunit mu, AP-4 adaptor complex mu4 subunit, Adaptor-related protein complex 4 subunit mu, Clathrin-adaptor medium chain Apm4, Mu4-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Early endosome.
Protein: NHAP2_SALPB
Sequence: MDAATIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGIGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFHLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIEMIQKHETGLDWMFAVHIIQQFGLGIVFGLGGGYLLQQMINRISLPSGLYPMLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVTPSDLWPIAVPALILSIWMIFFARPLSVFTGLLPFRGFNLRERIFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKRAKVVVPPVGWPVSRVGLDIHPDNPWEQFIYQLSADKWCVGAALRDLHMPNETRIAALFRNNELFHPTGSTRLQEGDVLCVIGRERDLPALGKLFSQSPPVSLDQRFFGDFILEANAKFADVALIYGLEEGTEYRDKQQTLGEIIQQLLGAAPVVGDQVEFGGMIWTVAEKEDNVVRKIGVRVAEDEAE
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLGC_DEIRA
Sequence: MKPRVLGMILAGGQGSRLAPLTQKRSKPAVPFGSKYRIIDFAINNFINSGMFSVYVLTQYKAQSLTEHIQRGWRFGTFLSDYFITLVPAQMYRFEELGDAWYRGTADAVYQNMHLIDNFEADYVAIFSGDHIYKMNVEHMLEKHIETRADVTIAAYPMPQSQAHQFGVMQVDERWRVTEFHEKVPDPPTIPGQADLSLTSMGNYIFSRRALEELLEASISGQETGYDFGHNVIPRALSDGYHVQAYDFHKNPIPGQERPNTYWRDVGTLDAYFEANMDLVSVNPEFDIYNPEWPLRTSSEFSPPAKFVHESEGRKGQAFNSIMAGGAIISGGTVRDSVLGRNVRTHSYSLVESCVLFDDVQVGRHSHLRRVIVDKDVVIPPGTTIGLNREHDEQRGFTVTEHGVVVVPKGYVF
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: LIN28_CAEBR
Sequence: MSTVVSEGRNGGNERYSPQDDVSKELPDINGLSLEETMGIPSFDRLPSPTPRYFGSCKWFNVSKGYGFVIDDNTGEDLFVHQSNLNMQGFRSLDEGERVSYYIQERSNGKGKEAYAVSGEVEGQGLKGSRIHPLGRKKAVSLRCFRCGKFATHKAKGCPNVKTDAKVCYTCGSEEHVSSVCPERRRKHRPEQVAAEEAEAARLAQEEADRSSPEENERKDGKLVEQKETETADKAGK
What is the function of this protein?
Heterochronic protein which controls the choice of stage specific cell fates (By similarity).  Regulates the timing of the second larval stage events (L2 events) in the hypodermis (By similarity).  May negatively regulate the larval to adult transition via the suppression of the microRNA (miRNA) let-7 during L3 (By similarity).  Through this regulatory role, controls the timing of the sexual maturation of the nervous system (By similarity).  Plays a role in governing the developmental timing of male tail tip morphogenesis (By similarity).  Plays a role in the control of seam cell number and vulval development (By similarity).
What are the official names of this protein?
Protein lin-28, Abnormal cell lineage protein 28.
What is the protein family that this protein belongs to?
Belongs to the lin-28 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_RHIWR
Sequence: MGSMSIWHWLVVGVLVLLLFGKGRFSDMMGDVAKGIKSFKKGMSEEDEPTQPAEPRPTPRLQQQPPIEPNADPKLQPMQDDRPQH
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RBFA_DICT6
Sequence: MRQRQERLSALIREEISEILLRRVKDPRISSFLVITEVKMSKDLRYAHIYVSVYGSEEEKKQTMQGLESAKGFIRSELGKDLRIRFVPEIFFELDDSLEKGDRILRKLKELGLEDEQDSE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_GRAFK
Sequence: MAKITAAEVNKLRKATGAGMMDCKKALVEAEGDFDGAIELLRKKGQKVAAKRADRDSSEGAAIAQVNGDNTKGVIISLNCETDFVAKNDDFIKMANNFAEIALNYSSKEEFLKADYKGISVEDKLTEQTGVIGEKIEIGAFRTLEAPFVGSYIHAGNKIAVLTGLSKSVDGAEEAAKNVSMQAAAMNPVALNEEGVDQGTIDKEIEIAKDTLREEGKPENMLDKIAQGKLQRFFKDNTLVHQAYIKDNKQSVADYVKTVDGALEVVAFERVALG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOP16_SCLS1
Sequence: MGRELQKKKNRSGNAKIKLKPKSKRVNPLGNAIIAANWRQEETLTQNYRRLGLTSRLNTVTGGIEKKKAGPESKTSTANKLAISNTIPKSLAPTEARVERDPETGKIIRVIHDEKKTNPLNDPLDSEAEDGEGEGFEGFGDEEGSASKNEIVKMLEEQASRAGEKRERQQSEREKEWIERLVKRWGENYGAMVRDRRLNPMQQTESDIKRRVQKWKDAGGSVTTEA
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Nucleolar protein 16.
What is the protein family that this protein belongs to?
Belongs to the NOP16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MIG10_CAEEL
Sequence: MDSCEEECDLEVDSDEEDQLFGEKCISLLSSLLPLSSSTLLSNAINLELDEVERPPPLLNVLEEQQFPKVCANIEEENELEADTEEDIAETADDEESKDPVEKTENFEPSVTMDTYDFPDPYPVQIRARPQVPPKPPIDTVRYSMNNIKESADWQLDELLEELEALETQLNSSNGGDQLLLGVSGIPASSSRENVKSISTLPPPPPALSYHQTPQQPQLLHHHNNHLGYQNGIHQITSINSAASSCSSPDGDSAFGDSSSTESSNNRCRNSAFSSNDSCRDSLNTPSPTQVSPRNGELNAEEAKAQKIRQALEKMKEAKVTKIFVKFFVEDGEALQLLIDERWTVADTLKQLAEKNHIALMEDHCIVEEYPELYIKRVYEDHEKVVENIQMWVQDSPNKLYFMRRPDKYAFISRPELYLLTPKTSDHMEIPSGDQWTIDVKQKFVSEYFHREPVVPPEMEGFLYLKSDGRKSWKKHYFVLRPSGLYYAPKSKKPTTKDLTCLMNLHSNQVYTGIGWEKKYKSPTPWCISIKLTALQMKRSQFIKYICAEDEMTFKKWLVALRIAKNGAELLENYERACQIRRETLGPASSMSAASSSTAISEVPHSLSHHQRTPSVASSIQLSSHMMNNPTHPLSVNVRNQSPASFSVNSCQQSHPSRTSAKLEIQYDEQPTGTIKRAPLDVLRRVSRASTSSPTIPQEESDSDEEFPAPPPVASVMRMPPPVTPPKPCTPLTSKKAPPPPPKRSDTTKLQSASPMAPAKNDLEAALARRREKMATMEC
What is the function of this protein?
Required cell non-autonomously for proper development of the excretory canals and for the long-range anterior-posterior migrations of embryonic neurons CAN, ALM and HSN (PubMed:9142991, PubMed:2361334).  Plays a role, probably downstream of ced-10/rac1, in orientating axonal growth of HSN and AVM neurons in response to guidance cues such as slt-1 (PubMed:18499456).  May regulate growth cone polarization by promoting asymmetric F-actin assembly (PubMed:18499456).  May be involved in signal transduction during cell migration (PubMed:9142991).
What are the official names of this protein?
Abnormal cell migration protein 10.
What is the protein family that this protein belongs to?
Belongs to the MRL family.
What are the subcellular locations of this protein?
Perikaryon. Note=Enriched at the ventral edge of HSN cell bodies. This asymmetric distribution is regulated by ced-10/rac1.
Protein: HRH3_HUMAN
Sequence: MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWK
What is the function of this protein?
The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system.  Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist).  Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.
What are the official names of this protein?
Histamine H3 receptor, H3R, HH3R, G-protein coupled receptor 97.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y07A_ARCFU
Sequence: MSYARGEKIDGVIFLVEETDDGYTARALGHSIFTQAGSLEELKEMVKDAVECHFEEGERPKLSDFT
What are the official names of this protein?
UPF0150 protein AF_0072.1.
What is the protein family that this protein belongs to?
Belongs to the UPF0150 family.
Protein: UVRB_CAMJR
Sequence: MLELTSEFKPSPDQQEAIKGIVKSIKKGNKYQTLLGVTGSGKTFTMANVIKELNIPTLIMSHNKSLCAQLYSEFKGFFSKNHVEYFISYYDYYQPEAYIPRTDVFIEKDSSTNEDLERLRLSATASLLSYEDVVCIASVSANYGLGNPNEYIGMVLIFELGMQISQKELLKKLVDMGYKRNDNFFDRADFRVQGDIIDIYPAYYEDEVVRLEFFGDELDAMYHYNVLENKKGKDLKRFILYPTSQFSVGETRLKQAIKDIKAELNERLAYFEHENKLVEYQRLKQRVEFDLEMLTSTGMCKGVENYARHLTGLKEGDTPYTLFDYFAIKNRKFLVIVDESHVSLPQFRGMFAGDRSRKQTLVDYGFRLPSALDNRPLMFDEFIHKNCQFLFVSATPAPLELELSKENIFHQIMRPTGLLDPLIELKDSDNQVEILFDEAKKVIQRNERVLVTVLTKKLAEELTRYYLELGIKVKYMHSDIDAIERNEIIRGLRSGAFDMLIGINLLREGLDLPEVSLIAIMDADKEGFLRSTTSLIQTMGRAARNVNGKVLLFCKKITKSMQEAMDTTNERRKLQMAYNKKYNITPTSVKRHIEESLKNEEDLGEIYRKGKKLEKMPASERAKLAKELRKQMLEAAKALEFEKAAAIRDEINKLRDL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_ACTP2
Sequence: MELQVVGANALTVSETTFGREFNEALIHQVVVAYAAGARQGSRAQKTRAEVSGSGKKPWRQKGTGRARSGDIKSPIWRSGGITFAAKPQDHSQKVNKKMYRGAIKSILSELVRQERLVVVEKFEIEAPKTKVLVQKLKDLALNDALIITANLDENLFLAARNLYKVDVRDVQGIDPVSLIAFDKVVITADAVKQIEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SHAWN_DROME
Sequence: MATREACGQFAAASAAMAAASSQNPSKATMTDPRFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDTPNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQRMTHAEMFGTIRQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLKSSFGVVEPTFSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFEYGKSFFYHYNIDQHNRSNQATKGPGS
What is the function of this protein?
Mitochondrial transporter required for glutathione import into mitochondria.
What are the official names of this protein?
Solute carrier family 25 protein Shawn, Solute carrier family 25 member 39 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: G3P_SALTY
Sequence: MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDAEYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGIFLTDETARKHITAGAKKVVLTGPSKDNTPMFVKGANFDKYEGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIPC_DANRE
Sequence: MSNRPNSNPGGSLRRSQRNTAAAQPIDHTLAGRNSLSLSVGSLSIPDPDLEAAGTSGQQGRREGSSTRALKRSSVSEPNITFSPSPAKRPKVVSSHFSDSSASGPSAPAISPEVTEPRKAPASVSTKSKKRRLAAEPAPARALSKKSSSYPGPSGASSTPSQKRKKADATLLSSSSSSSLPSSSSAAGPLPPRSEASRAAKPTKLASKSAASAKAGCSTVTDSSSSSASSSSSSSSSSSAATGTNSCAPQGARLKQGKDQSKARRSRSASSPSPRRSSRDKEQSKAAGSSKFDWASRFNSKVNLPKPKLSLPGSAKAETSSKPGPSGLQAKLASLRKSTKKRSESPPAELPSCRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADSDNNQDGANSSAARTEETPQGASASSSVAGAVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPFGPRMSQLFHRTIGSGASSKAQQLLQGLQATGDESQQLQAAIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHASRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQFIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASRDLLTNIQQLLVLTPPVLSSGMFIMVVRMFSLMCSNCPCLAVQLMKQNIAETLRFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPREGIFAVDAMLKKGSAQTTEGAIWQWRDDRGLWHPYNRIDSRIIEQINEDTGTARAIQRKPNPLANPNTGGHLEVRREDARAQLMKEDPELAKCFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLRNHAVSSHIASMLSSQDLKIVVGSLQMAEILMQKLPDVFSVYFRREGVMHQVKNLAESEVFLTSPPKACTSGTASLCTTTITTATTTAASNVTPDLGSPSFQHSMDDSLDLSPQGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKSPTTTQSPKSSFLASLNPKTWGKLGTQANSANSEPSRTAGVSGLARVPPKDSVSNNRDKIKAWIKEQASKFVERYFNSESVDGSNPALNVLQRLCTATEQLNLQMDSGVECLEEISSIVSESDVSSFEIQHSGLVKQLLLYLTSNSERDTISRDERIKRFLHVFFGCPIPGQEPPGRLDPTENGPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGNGSRGSQALKFFNTHQLKCQLQRHPDCTNVKQWKGGPVKIDPLALVQAIERYLVVRGYGRIREEDEDSDDDGSDDEIDESLAAQFLNSGSVRHRLQFYIGEHLLPYNMTVYQAVRQFSLQAEEERESTDDEANPLGRAGIWTKTHTVWYKPVREDEEGCKDAVGGKRGRAQTAPTKTSPRNAKKQDELWHEGVCPSVANPLETYLICDPPEGITFDDPSMEVILLLRVLHSISRYWFYLYDNAACKEIIPTGEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTINRDELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTQEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYMFSSRGLFAVPFGRTTKPAHIAKIKMKFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHESSISSHDLVNIDPGVAKSIQHLEDIIRQKKRIEQDRSHTRETLQQALESLNMNGCSVEDLGLDFTLPGFPNIELKKGGKDVPVTIHNLEDYLRLVVYWTLNEGVLRQFESFREGFESVFPLHHLQYFYPEELDQLLCGSKSESWDVKTLMECCRPDHGYTHDSRAVRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGQQSFHLS
What is the function of this protein?
E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair.  Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.  Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spreading of ubiquitinated chromatin at damaged chromosomes.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIP12, HECT-type E3 ubiquitin transferase TRIP12, Thyroid receptor-interacting protein 12, TR-interacting protein 12, TRIP-12.
What is the protein family that this protein belongs to?
Belongs to the UPL family. K-HECT subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: KYNU_MONBE
Sequence: MHLARELGVNLADQRLAQALDEADPLAHLRQEFSIPQMKDIKQADLKLVEAESDCIYLCGNSLGLMPKRTRTIVNEELDTWATGGVTGHFPDGPGKRPWVSIDETVTDKCARVVGALPEEVAIMNTLTVNLHLLMVSLAHTMARQVPFYRPTSDRFKILVEAKAFPSDHFAVLSQLRMHGHDESALIEVKPREGEHNIREEDLLAILEEQGDSIATVLVGGVHYYTGQFFDLQRLCAAAHNKGCTFGVDLAHAVGNVPLQLHDWDIDFACWCTYKYLNSGPGGIAGAFIHKKHEGTSRPYLQGWWGVQLNERFRMDHDASFMPGVRGLQLSNPGVLQTVALLGSLEIYEQTDMASLRAKSLKLTAYLEQLMQALVNEEGHAPRFEIITPTDPERRGCQLSILFKVDIDAAFEALEKRGVVCDVRRPDVMRIAPVPLYNTFTDVYRFVTTLRDALNASASS
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_ARTS2
Sequence: MIQQESRLKVADNTGAKEILTIRVLGGSGRRYAGIGDVIVATVKDAIPGGNVKKGDVVKAVIVRTKKERRRADGSYIKFDENAAVILKNDGDPRGTRIFGPVGRELRDKKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CH10_JANSC
Sequence: MALKPLQDRVLVRRVESEEKTAGGLIIPESAKEKPSEGEVVSCGDGARKDSGELIEMTVKTGDRILFGKWSGTEVTLDGEELLMMKESDILGIIT
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_BURA4
Sequence: MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPGFFAGVCTVVTKLMSCVQPRVAVFGKKDYQQLMIVRRMCQQLALPVDIIAAETVRDEDGLALSSRNRYLTTDERKEAPELAKTLQRVRDGVLGGERDLGKLEQTARTHLAERGWAPDYISIRRRANLIAPSAAELEAGEPLVVLAAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_BORBR
Sequence: MNDILAKILAVKAEEVATARQMRSEAELLREAQARQDVRGFAQAIEDKISQGKAGVIAEIKKASPSKGVLRENFDPAEIAASYAMHGAACLSVLTDVQFFQGSHDNLRRARAACSLPVLRKDFIIDPYQIISARAMGADCVLLIVAALAPAQLRDLETLAIDLGMDVLVEVHDAKELDAALALRTPLIGINNRNLRTFETTLQTTLDLLPMIPAGKRVVTESGILKPEDVRLMREHDVQAFLVGEAFMRANDPGVELARLVA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.