PharMolix/UniProtQA huggingface dataset:
Protein: RSMG_STRPM
Sequence: MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAITEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDSLNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELTIPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKKKETPNKYPRKAGLPNKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCHM_BPT2
Sequence: MISDSMTVEEIRLHLGLALKEKDFVVDKTGVKTIEIIGASFVADEPFIFGALNDEYIQRELEWYKSKSLFVKDIPGETPKIWQQVASSKGEINSNYGWAIWSEDNYAQYDMCLAELGQNPDSRRGIMIYTRPSMQFDYNKDGMSDFMCTNTVQYLIRDKKINAVVNMRSNDVVFGFRNDYAWQKYVLDKLVSDLNAGDSTRQYKAGSIIWNVGSLHVYSRHFYLVDHWWNTGETHIVKKDYNGEWK
What are the official names of this protein?
Deoxycytidylate 5-hydroxymethyltransferase, Deoxycytidylate hydroxymethylase, dCMP hydroxymethylase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: ATPA_CLOBK
Sequence: MNIKPEEITSIIRQQIENFNTNIETIDSGTIIQIGDGIARVYGLEDCMEGELIEFPNDVYGMALNLEQDNVGCVLLGAEEGIKEGNVVKRTKKVVEVPVGEALVGRVVNSLGMPIDGKGPVLTTETRDVEVPAPGVIDRQSVKEPLQTGIKAIDSMIPIGKGQRELIIGDRQTGKTAIAMDTILNQKGKDVICIYVAIGQKQSTVAHIVNDLTKMGAMDYTIVVSSTASDSAPLQYLAPYAGCSMGEYFMHKGKDVLIVYDDLSKHAVAYRTMSLLLRRPPGREAYPGDVFYLHSRLLERSARLSEKLGGGSLTALPIVETLAGDVTAYIPTNVISITDGQIFLESELFNAGQRPAVNAGISVSRVGGNAQIKAMKQVAGTLRLELAQYRELAAFSQFGSDLDKESVKRLEKGKRLVEILKQPQYGPMPVEKEIIILYAAVNNHLIDIPVNKIKEFEKELFNYIDTHYRDIGKDILEHKQLTDELKSKLDKAINDFKNVFLSEI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS3_STAAW
Sequence: MGQKINPIGLRVGIIRDWEAKWYAEKDFASLLHEDLKIRKFIDNELKEASVSHVEIERAANRINIAIHTGKPGMVIGKGGSEIEKLRNKLNALTDKKVHINVIEIKKVDLDARLVAENIARQLENRASFRRVQKQAITRAMKLGAKGIKTQVSGRLGGADIARAEQYSEGTVPLHTLRADIDYAHAEADTTYGKLGVKVWIYRGEVLPTKNTSGGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: CHLI2_ARATH
Sequence: MASLLGRSPSSILTCPRISSPSSTSSMSHLCFGPEKLSGRIQFNPKKNRSRYHVSVMNVATEINSVEQAKKIDSKESARPVYPFAAIVGQDEMKLCLLLNVIDPKIGGVMIMGDRGTGKSTTVRSLVDLLPEITVVSGDPYNSDPRDPECMGKEVREKVQKGEELSVIETKINMVDLPLGATEDRVCGTIDIEKALTEGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISISHPARFILIGSGNPEEGELRPQLLDRFGMHAQVGTVRDAELRVKIVEERARFDSNPKEFRETYQEEQLKLQEQITTARSNLSAVQIDQDLKVKISKVCAELDVDGLRGDMVINRAARALAALQGRDQVTAEDVGIVIPNCLRHRLRKDPLESMDSGILVTEKFYEVFT
What is the function of this protein?
Involved in chlorophyll biosynthesis.  Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.  The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step.  Possesses low affinity for ATP and may play a limited role in chlorophyll biosynthesis, and contributes to the assembly of the Mg-chelatase complex.
What are the official names of this protein?
Magnesium-chelatase subunit ChlI-2, chloroplastic, Mg-chelatase subunit I-2, Mg-protoporphyrin IX chelatase subunit ChlI-2.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFTU_BORBU
Sequence: MAKEVFQRTKPHMNVGTIGHVDHGKTTLTAAISIYCSKLNKDAKALKYEDIDNAPEEKARGITINARHIEYETANRHYAHVDCPGHADYIKNMITGAAQMDAAILLVAADSGAEPQTKEHLLLAQRMGIKKIIVFLNKLDLADPELVELVEVEVLELVEKYGFSADTPIIKGSAFGAMSNPEDPESTKCVKELLESMDNYFDLPERDIDKPFLLAVEDVFSISGRGTVATGRIERGIIKVGQEVEIVGIKETRKTTVTGVEMFQKILEQGQAGDNVGLLLRGVDKKDIERGQVLSAPGTITPHKKFKASIYCLTKEEGGRHKPFFPGYRPQFFFRTTDVTGVVALEGKEMVMPGDNVDIIVELISSIAMDKNVEFAVREGGRTVASGRILEILE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_NITEC
Sequence: MQTKARLPVDINAPSLQSPALGIDTHLLRGELRQHEPMKQHVSWRAGGHAAYFYQPADLEDLAVFLHFWPKDEPVMMIGLGSNFLVRDGGLPGVMIALHAKLNDLLLVEQEEDGGLIYAGAGVPCAKLARFASLHNLAGAEFLAGIPGTVGGALAMNAGCYGSETWERVERVKTIDRDGTLHERTPEDYRIGYRQVELHEVVPPDTSCSWFVGGWFRLRPGQQESSRQAVKALLGTRIKTQPLGFPSAGSVFRNPPGDYAARLVEQCGLKGFRIGDAMISTLHANFIINCGHATATEIETVINTVQDIVYKKTEIRLVTEVRIIGQHKGNEL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_HASV
Sequence: MGDAGVASQRPHNRRGTRNVRVSANTVTVNGRRNQRRRTGRQVSPPDNFTAAAQDLAQSLDANTVTFPANISSMPEFRNWAKGKIDLDSDSIGWYFKYLDPAGATESARAVGEYSKIPDGLVKFSVDAEIREIYNEECPVVTDVSVPLDGRQWSLSIFSFPMFRTAYVAVANVENKEMSLDVVNDLIEWLNNLADWRYVVDSEQWINFTNDTTYYVRIRVLRPTYDVPDPTEGLVRTVSDYRLTYKAITCEANMPTLVDQGFWIGGQYALTPTSLPQYDVSEAYALHTLTFARPSSAAALAFVWAGLPQGGTAPAGTPAWEQASSGGYLTWRHNGTTFPAGSVSYVLPEGFALERYDPNDGSWTDFASAGDTVTFRQVAVDEVVVTNNPAGGGSAPTFTVRVPPSNAYTNTVFRNTLLETRPSSRRLELPMPPADFGQTVANNPKIEQSLLKETLGCYLVHSKMRNPVFQLTPASSFGAVSFNNPGYERTRDLPDYTGIRDSFDQNMSTAVAHFRSLSHSCSIVTKTYQGWEGVTNVNTPFGQFAHAGLLKNEEILCLADDLATRLTGVYPATDNFAAAVSAFAANMLSSVLKSEATSSIIKSVGETAVGAAQSGLAKLPGLLMSVPGKIAARVRARRARRRAARAN
What is the function of this protein?
Self-assembles to form an icosahedral capsid with a T=4 symmetry, about 35 nm in diameter, and consisting of 240 copies of the two structural proteins.
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the tetravirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: SPT19_HUMAN
Sequence: MIITTWIVYILARKGVGLPFLPITSSDIDVVESEAVSVLHHWLKKTEEEASRGIKEKLSINHPSQGVREKMSTDSPPTHGQDIHVTRDVVKHHLSKSDLLANQSQEVLEERTRIQFIRWSHTRIFQVPSEMTEDIMRDRIEQVRRSISRLTDVSAQDFSMRPSSSDC
What is the function of this protein?
Essential for sperm motility and male fertility (By similarity).  Plays an important role in sperm motility by regulating the organization and function of the mitochondria and is also required for correct sperm midpiece assembly (By similarity).
What are the official names of this protein?
Spermatogenesis-associated protein 19, mitochondrial, Spermatogenic cell-specific gene 1 protein, Spergen-1.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Mitochondrion. Cell projection, cilium, flagellum. Note=Localizes to the midpiece of the sperm flagellum.
Protein: CH60_RAOOR
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIIAEGLKAVAAGMNPMDLKRGIDKAVVAAVEELKTLSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLEDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKVSNIREMLPVLEAVAKAGKPLVIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEGAIQGRVAQIRKQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVDDALHATRAAVEEGVVAGGGVALVRVAAKLAGLTAQNEDQNVGIKVALRAMEAPLRQIVSNAGEEPSVVANNVKAGEGNYGYNAATEEYGNMIDFGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKSDAADLGAAGGMGG
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_PSEA7
Sequence: MSQTTPAVRTFQDLILALQNYWAEQGCVVLQPYDMEVGAGTFHTATFLRAIGPETWNAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVLKPNPENFQELYLGSLKAIGIDPLVHDIRFVEDNWESPTLGAWGLGWEIWLNGMEVTQFTYFQQVGGIECYPVTGEITYGLERLAMYLQGVDSVYDLIWTDGPFGKVTYGDVFHQNEVEQSTFNFEHANVPKLFELFDFYESEANRLIELELPLPTYEMVLKASHTFNLLDARRAISVTERQRYILRVRTLARAVAQSYLQARARLGFPMATPELRDEVLAKLKEAE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_NOSS1
Sequence: MGRSLKKGPFIADHLLSKIEKLNDRNEKQVIKTWSRASTILPLMVGHTIAVHNGRQHVPVFISEQMVGHKLGEFAPTRTYRGHGKSDKKAGR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SYC_POLNS
Sequence: MLQIYNTLSRSKQVFKPIVPGKVKMYVCGMTVYDFCHIGHARVMIVFDMVVRWLRASGYEVLYVRNITDIDDKIINRAIENGEPISALTNRFVDAMHADSDELGLMHPDQEPRATDYIAQMQGMIGKLIENELAYQANDGDVNFAVRLLPRYGQLSGKTLDELNAGERVAVGDGKRDPLDFVLWKSAKPEEPADTRWKSPWGEGRPGWHIECSAMSCDLLGEHFDIHGGGADLQFPHHENEIAQSEGALYGKDRKVDDAPFVNYWMHNGHIRVNEEKMSKSLGNFFLIRDVLKSFDPEVIRFFMLKTHYRSPINYSDAQLEEARSGLVRLYTALAQGSKAQTISLGSSNPWAKRFADAMNDDFNTPEAIAVLFDIVSEVNRAQGEEKQVLANILKALGASLNFLQRDPTVFLQSSAKDQAGLSPEQIEEQIAARVAAKQAKDFAKADAIRKALLEQGIVLEDKPGGLTGWRRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_DICTD
Sequence: MSRIGRKPVPIPQNVQVEIKDGNCVSVKGPLGQIEKTFSPLLTIKKVDNQIVVERPNDEKFVKALHGLTRALINNMVLGVTQGFEKRLELQGTGYRARVQGNKLVLEVGFSHPVELEIPTGLTVSVQDNTKISVKGIDKELVGQFAAIVRSVRPAEPYKGKGIRYEGEKIRQKAGKAGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL2_ORITI
Sequence: MALKVYNSVTQSLRQVVQVDKSELWKGRPLKKLAKGITKTGGRNNLGRITIWHRGKGHKQLYRMIDFKRRVFDIYATVERIEYDPNRTAFIALIKYDDGKFSYILSPRNLNVGDKIISSDKAEINVGNCLPLEVIPVGTIIHNIEIKPGKGGQVARSAGTYAVLLNKDSGYAQIKFRSGEVRRISLASRATVGSVSNIDHKNISYGKAGRVRWLGRRPVVRGVAMNPVDHPHGGGEGKTSGGRHPVTPWGKKTKGKKTRKNKFTSRFIVKRRN
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: FNTB_ARATH
Sequence: MPVVTRLIRLKCVGLRLDRSGLNRRICHGGHGESTRRRVMEELSSLTVSQREQFLVENDVFGIYNYFDASDVSTQKYMMEIQRDKQLDYLMKGLRQLGPQFSSLDANRPWLCYWILHSIALLGETVDDELESNAIDFLGRCQGSEGGYGGGPGQLPHLATTYAAVNALVTLGGDKALSSINREKMSCFLRRMKDTSGGFRMHDMGEMDVRACYTAISVASILNIMDDELTQGLGDYILSCQTYEGGIGGEPGSEAHGGYTYCGLAAMILINEVDRLNLDSLMNWAVHRQGVEMGFQGRTNKLVDGCYTFWQAAPCVLLQRLYSTNDHDVHGSSHISEGTNEEHHAHDEDDLEDSDDDDDSDEDNDEDSVNGHRIHHTSTYINRRMQLVFDSLGLQRYVLLCSKIPDGGFRDKPRKPRDFYHTCYCLSGLSVAQHAWLKDEDTPPLTRDIMGGYSNLLEPVQLLHNIVMDQYNEAIEFFFKAA
What is the function of this protein?
Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X (CaaX) (PubMed:20565889).  The beta subunit is responsible for peptide-binding (PubMed:20565889).  Acts as an abscisic acid (ABA) negative regulator by mediating ASG2 farnesylation and consequently monitoring its subcellular localization (PubMed:26147561).  Involved in responses to salt (NaCl) and osmotic (e. g.  in response to mannitol and PEG) stresses (PubMed:26147561).
What are the official names of this protein?
Protein farnesyltransferase subunit beta, FTase-beta, CAAX farnesyltransferase subunit beta, Enhanced response to abscisic acid 1, Ras proteins prenyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit beta family.
Protein: LEC_LATSP
Sequence: TETETTSFSIPKTDQPSSPKFVSGQPNLIFQGNAYSTDGKLILTEAKQNTVGRALYSAPIHIWDRKTGKVADFTASFTFYIRPNSDSQVVADGFTFFIAPVDTQPRGDGGLLGVFNREEYDPTIHTVAVEFDTFHNQPWDPDYIHIGVDINSIKSRITRPWNPHYDTYSIAYIAYKAATNELDVTVTYPNSRDYATLREVVDLKQIVPEWVRVGLSASTATYYSAHEVYSWSFHSELGGTSSSN
What are the official names of this protein?
Lectin.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: COAE_ECOL6
Sequence: MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQRATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNGAPDAIASDVARLHAYYLQLASQFVSQEKP
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T6G_TERSU
Sequence: MATSGRLLCVCLVMGLVFESLGYLTGREKRPAENLEASVQRRWYLNRRYEVDCGGVLCQFGCCEDDRCRELGCEFMDVLSRIRSAE
What are the official names of this protein?
Teretoxin Tsu6.16.
What is the protein family that this protein belongs to?
Belongs to the teretoxin M (TM) superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1543_MYCTU
Sequence: MNLGDLTNFVEKPLAAVSNIVNTPNSAGRYRPFYLRNLLDAVQGRNLNDAVKGKVVLITGGSSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAIAVMADQVLGDLGGVDILINNAGRSIRRSLELSYDRIHDYQRTMQLNYLGAVQLILKFIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAETVHDNVRFTTVHMALVRTPMISPTTIYDKFPTLTPDQAAGVITDAIVHRPRRASSPFGQFAAVADAVNPAVMDRVRNRAFNMFGDSSAAKGSESQTDTSELDKRSETFVRATRGIHW
What are the official names of this protein?
Uncharacterized oxidoreductase Rv1543.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: UVRB_LEVBA
Sequence: MIDRQTDRAFDLVSKYQPTGDQPEAINQLTHGIEAGEKAQILLGATGTGKTFTISNVIKNVNKPTLVLSHNKTLAGQLYGEFKQFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSINDEIDKLRHSATSSLLERNDVIVVASVSSIFGLGDPTEYKNHVVSLRVGQEIERDALLRKLVNIQFERNDYDFQRGRFRVHGDVVEIFPASRDERALRVEFFGDEIDRIREVDALTGEIVGDREHVAIFPATHFMTNDDIMAQATAGIEGELKERLAELENDGKLLEAQRLKQRTTYDLEMMREMGYTSGIENYSRWMDGRQAGEPPYTLLDFFPKDFLLVVDESHVTMPQVRGMYNGDRARKQQLVDYGFRLPSALDNRPLKLNEVEQHINQVIYMSATPGPYEAEQTDHVVQQIIRPTGLLDPTIDVRPIMGQMDDLVGEINQRIEKNERTFVTTLTKKMAEDLTDYLKDLGIKVAYLHSDIKTLERTEIMRDLRLGKYDVLVGINLLREGIDIPEVSLVAILDADKEGFLRNERSLIQTIGRAARNSHGSVIMYADSVTDSMQAAMDETARRRQIQIAYNKEHGITPTTIIKPIRDLIAVSKKNDNAGEKDDFVASDFEDMTKEDQEKLIARLEDEMRAAAKKLDFEQAASLRDTIMDMKTEIGD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFU_NOSS1
Sequence: MWDYTDKVLELFYDPKNQGVIEENGEPGVKVATGEVGSIACGDALRLHIKVEVESDKIVDSRFQTFGCTSAIASSSALTEMIKGLTLDEALKVSNKDIADYLGGLPEAKMHCSVMGQEALEAAIYNYRGIPLAAHDEDDEGALVCTCFGVSENKVRRIVIENDLTDAEQVTNYIKAGGGCGSCLAKIDDIIKDVKENKAATNLNNKGGSKPTNIPNSGQKRPLTNVQKIALIQKVLDEEVRPVLIADGGDVELYDVDGDIVKVVLQGACGSCSSSTATLKIAIESRLRDRINPSLVVEAV
What is the function of this protein?
May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
What are the official names of this protein?
Nitrogen fixation protein NifU.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
Protein: TDH_FRAP2
Sequence: MKALAKLKKEPGIWMIDDAPMPEYGYNDVLIKIKKTAICGTDLHIYNWDKWSQATIPVPMITGHEFAGEVVAKGNGVTSVDVGDRVSGEGHLVCGQCRNCRAGKRHLCRKTIGIGVNVQGAFAEYLVMPAVNVFKIPDSISDDIASTFDPMGNAIHTALSFNLTGEDVLITGAGPIGLMAVKIARFCGARRIVITDINKYRLQMARDFGATVAVNVSEFQNQQQLTAQMRKVMSEIGMTEGFDVGLEMSGINSAISMMLDVMNHGGKLSLLGISAGDISVDWGAILFKGLTLKGIYGREMFETWYLMTSMLQAGMDMEPIITHRLHIDDYQKGFEIMKSGQCGKVILDWSR
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F172A_CHICK
Sequence: MHFYFNVLNLLTVWVMMAQLQQGVPDEKEKTTALKDLLSRIDLDELMKKDEPPLEFPDTLEGFEYSFNEKGQLRHAKTGEPFVFNYREDLHRWNQKRYEALGEIITKHVYGLLEKECHLKKVTLPVDATENEPKSFIFMSEDALTNPDKLLVLIHGNGVVRAGQWARRLIINEDLDSGTQIPYIKKATEEGYGVIVLNPNENYIEVEKTKAQVQLSSDSSDEPAEKRERKDKIQKETKKRRDFYEKYRNPQKEKETMQMYIRDNGSPEEHAIYVWDHFISQSAAENVFFVAHSYGGLAFVELMIQRETEVKNKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTERHELTSWKSFPSIFKFFSEAMEAKNSSVKPAPTRRSNRIKYEEL
What is the function of this protein?
May play role in the regulation of alternative splicing.  May have hydrolase activity.
What are the official names of this protein?
Cotranscriptional regulator FAM172A homolog, Protein FAM172A.
What is the protein family that this protein belongs to?
Belongs to the FAM172 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TRPF_METVS
Sequence: MFIKICGIKTPNELKIIEKYGDFTGVILECVSKRKIGVESAKNLIEISNIPVFAVSTTTEVLAWKNIIELTGTNYLQMHSNIDSKSVEAIKKEYGCFIMKSFKIPEKSEFPEIDAENIILDIERYEVDRILLDTGKGCGMVHDHRISQIIAKKFDIVLAGGLNTDNVSEIIKKVKPFGVDVSSGVENKNSKDEGLIKKFYENVKSVKL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: SYL_MYCGE
Sequence: MYNHNLIEEKWLKKWKNKDVNRFESDSNKKKYYVLDMFPYPSAAGLHLGHVRAYTITDVISRYYKAKGFNVIHPIGFDAFGLPAEQYAINSNQNPGSWTDQNINNFINQLTSFGFDYDYHLSLKTTDPRYYKYTQWIFSELFKANLAELVDIDVNWCEQLGTVLANEEVLIDSNGNAVSERGSFSVEKRKMKQWVLKITTFADALLEGLDTLDWPEPIKEMQRNWIGKSKGVTINFQLKDHKEAIAIFTTKPQTIFGVSFLAVSTNHWLAKKIAETNKKVASFLKKQLQKTTTLKQKATLYDGIDLLTNAIHPLTNELIPVYVANYVIEGYGTDAIMGVGAHNENDNFFARKQKLKIINVIDKKERLQNSFAYNGLTTKEAQVAITNELISQNKAKLTTVYKLRDWIFSRQRYWGEPFPIIFDENNTPHLVEQLPVELPLLENYKPDGSGNSPLMRNQAWVNIVKDNIHYQRETNTMPQWAGSCWYYLGYLMLIKNPNFWPIDSKEAKKLFDQYLPVDLYVGGAEHAVLHLLYARFWHKFLFDKKLVSTKEPFQKLINQGMVLGPDGKKMSKSKGNTINPTPLVDSHGADALRLYLMFMGPISASLTWNDEGLNGMRRWLDRVYNFFFNHAVVTDQVSQETIFAYNLFLKNSYCHLDKHELNLVISEMMIFLNFLYKTKKISLNYAKGFLTVLSFFAPFLAEELNEKCGLEPFVVKQAISLVDYQLFETAKTKVILSINGKFKAAKEFTKGSLEIDVLESFKQDKEINDILNQPIERVVYVQDRIINVLLKK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFT20_MOUSE
Sequence: MAKDILGEAGLHFDELNKLRVLDPEVTQQTVELKEECKDFVDKIGQFQKIVGGLIELVDQLAKEAENEKMKAIGARNLLKSIAKQREAQQQQLQALIAEKKTQLERYRVEYEALCKVEAEQNEFIDQFIFQK
What is the function of this protein?
Part of intraflagellar transport (IFT) particles involved in ciliary process assembly.  May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium (PubMed:16775004).  Regulates the ciliary platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway.  Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling (PubMed:29237719).  Essential for male fertility.  Plays an important role in spermatogenesis, particularly spermiogenesis, when germ cells form flagella.  May play a role in the transport of flagellar proteins ODF2 and SPAG16 to build sperm flagella and in the removal of redundant sperm cytoplasm (PubMed:27682589).  Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment (PubMed:24089209).
What are the official names of this protein?
Intraflagellar transport protein 20 homolog, mIFT20.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cytoplasm, cytoskeleton. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle, acrosome. Cytoplasm. Note=Present at the centrosomes during the cell cycle and associated with the proximal portion of the mother centriole and the lateral aspect of the daughter centriole (PubMed:15337773). Associated with basal body at the base of primary cilia (PubMed:15337773). Detected in the Golgi apparatus of round spermatids and late spermatocytes (PubMed:19889948, PubMed:28619825). Also detected in the manchette of step 10-12 spermatids (PubMed:19889948, PubMed:28619825). In step 14 spermatids, found in the basal body of the sperm tail (PubMed:19889948). Localization in the manchette of elongating spermatids is dependent on SPAG17 (PubMed:29690537).
Protein: Y5536_DICDI
Sequence: MINNSSKVRENGESYDVDLVVNLTVKIRFFREWINFIFVIYVGDYG
What are the official names of this protein?
Putative uncharacterized protein DDB_G0283463.