PharMolix/UniProtQA huggingface dataset:
Protein: NDB27_VAEME
Sequence: MNAKTLFVVFLIGMLVTEQVEAGIWSSIKNLASKAWNSDIGQSLRNKAAGAINKFVADKIGVTPSQAASMTLDEIVDAMYYD
What is the function of this protein?
Displays significant potent antimicrobial activity against clinical isolates of Gram-negative multidrug resistant strains of E. coli, P. aeruginosa and A. baumanii with MIC values as low as 4. 4 uM.  Additionally, it displays low cytolytic and hemolytic activity against human erythrocytes reaching 50% hemolysis at 100 uM.
What are the official names of this protein?
Vejovine, Non-disulfide-bridged peptide 2.7, NDBP-2.7.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: NAA40_MOUSE
Sequence: MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSIPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRTKFGDSQHSHTGGHCGGCCH
What is the function of this protein?
N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (By similarity).  In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' (By similarity).  Acts as a negative regulator of apoptosis (By similarity).  May play a role in hepatic lipid metabolism (PubMed:22231784).
What are the official names of this protein?
N-alpha-acetyltransferase 40, N-acetyltransferase 11, N-alpha-acetyltransferase D, NatD, Protein acetyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. NAA40 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NCPP_METKA
Sequence: MKVRVGTTNPVKVRATERAFLRTFPDREITVEAVSVDPGVPPQPVGMEEVHQGAKNRAREAWNRGSYSVGLEAGLIRVGDVYVDLHVAVVRDPKGRETVGTSPGFQLPPDVTEEALSGEEVGEVFSELVGVREIGKRSGAIGVLSNGKVLREDLCELAILMALIGLETSR
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Probable inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: SYGA_DESAP
Sequence: MDFQELIMTLDRFWGDRGCIIQQPYDVEKGAGTMNPATFLRVLGPEPWNVAYVEPSRRPTDGRYGENPNRLQHYYQYQVILKPSPDDVIEVYLDSLRAIGINPLEHDIRLVEDNWESPTLGAWGLGWEVWLDGMEITQFTYFQQCGGFDLKPVSAEITYGLERLALYLQGRDSVFDITWTGDITYRDVHFQGEVEHSRYNFEIADVELLHDLFEGYEREAQAVLEQQLVLPAYDYVLKCSHVFNLLDARGAISVTERTGYIARVRALARDCAKAYVAQRERLGFPLLKGGAPDGR
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_PICTO
Sequence: MDIINCSDNDLDLIGKSLALSHDEMLLIKKYFTEIKRNPSDVELQAIAQSWSEHSCYKSSKFYLKKYLSNLRNERTILAMEDDAGVVKFNDDYVYVVKMESHNHPSAVEPYGGAATGVGGIIRDVLCMGAQPVALVDSLYFGDPDNKSGFLSERFIINGVVSGIRDYGNRLGIPNVAGSIYFHEGYNTSPIVNAGCIGISRKDKIVRSRVQKARDILILCGGRTGRDGIHGVNFASRVLDLKNGENRNAVQLGNPIVEEPLIHAILELNDLGLITGMKDLGGGGLSSAVTEMLYAGNLGGTINLDSVLLKDDNMLPWEIWISESQERMLISSDERNLPQIKDVLDKWNIEFSVIGRAEEKKNLEIYYKNEKVFDLPLEFISKTPVYQRPYKKPRNRCKSEPFRDDDINKSIISLISSINVCSRAPVIRQYDHTVRGATIVRPLTGLPNNETHSDAAVIKPVDDSFAGIAVTSGSKPMLCTIDPYGGALESLIEAYKNIIVTGAEPDAIVDSLNFGNPENEETMYSFVETLKAIRDFTLKFKLQLVSGNVSFYNKNVSDIMPTPNIMMTGIIDDVRKAITTEFKNKNSLIYLIGSINGSLAGTVYSKLKDIKCYDYHNSNINDLCNVYNIIKENKEKILAAHDVSDGGIIAALIEMSFGKNIGFNVNLKDIKMNLENKLFSEHGTAIVIEVPLESEIVFNNLGIKLGYTCDDITVMDGENMVFNARISELKNLWDSGLGKYL
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA_STRPF
Sequence: MKRIAVFPSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE_STUS1
Sequence: MATLLSERGAQASWRDYLELTKPKVVLLMLITSLVGMFLATRAGVPWTVLLFGNLGIALCAGGAAAVNHVVDRQIDSVMARTHKRPLAEGRVSPAAALTFAFVLGVSGLALLLTFTNALAAWLTLASLIGYAVIYTGFLKRATPQNIVIGGLAGAAPPLLGWVAVTGQVTAEPLLLVLIIFAWTPPHFWALAIHRKDEYAKVNVPMLPVTHGVHYTKVHILLYTAMLLAVSFMPFAIHMSGPLYLAAAVLLGARFLYWTIALYRDSRPHAAIKTFKFSIWYLFALFIALLVDHYLLLDF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
Protein: Y1969_DESHY
Sequence: MAKDSSFDIVSKVEMQEVINAVHQAQKEIEQRFDFKNSKSSLELQDEKIILVSDDDFKLRNVIDILESKLVKRQVSLKALEYGKVQPAAGDTVRQEVKLVQGISQDKGKEINKLIKDSKIKVSSSIQGDQVRVTGKNKDDLQEVIALLRKQDLGIDLQFINYR
What are the official names of this protein?
UPF0234 protein DSY1969.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: BLCAA_XENLA
Sequence: MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCTICALVFLGALFLICYSCWGNCFLYHCSASELPEAAHDPAVVGT
What are the official names of this protein?
Bladder cancer-associated protein A.
What is the protein family that this protein belongs to?
Belongs to the BLCAP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: METK_HALS3
Sequence: MTDRNIQVQSLDRSAVEDDAVEIVERKGLGHPDSICDGIAEHVCETLAREYRDRVGHVLHFNTDETQLVAGDAAPAFGGGNVIDPIYILVVGRATSHYVEADGTEHHIPVESIALEAAREYLRETLPHLDLETDVIVDVKLGEGSGDLQDVFTDDDDGPAVPMANDTSFGVGHAPLTETERIVLEAERSLNGPYAEHTPAVGEDVKVMGKREDDHIDLTIAAALVDAHVPDMDAYIAQVEAIREHVFDLATEHTDREVTVHVNTADDYESGSIYLTTTGTSAEQGDDGSVGRGNRANGLITPNRAMSMEATSGKNPVNHIGKIYNLLSTQIAEAVVAEVDGIRDLRVRLLSQIGRPIDEPHVADVEVVTEDGTAVADVDAEIERIVDAQLASVTDLTRRVIDGERTTF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: YEGS_ECOL5
Sequence: MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRITWEKGDAARFVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATSVGIPEALDKALKLAIAGNAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALGGVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALINDGLLQLRIFTGDEIIPTLVSTLKSDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQNFHIEILPAALRCRLPPDCPLLR
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_ECODH
Sequence: MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQWAGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVGQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQNQDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PYRC_YERPB
Sequence: MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDVKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: HEMA_I73A5
Sequence: MKTIIALSYIFCLVLGQDFPGNDNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGKICNNPHRILDGINCTLIDALLGDPHCDGFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFINEGFTWTGVTQNGGSNACKRGPDSGFFSRLNWLYKSGSAYPVLNVTMPNNDNFDKLYIWGVHHPSTDQEQTNLYVQASGRVTVSTKRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDILVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIGTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: SRPRB_HUMAN
Sequence: MASADSRRVADGGGAGGTFQPYLDTLRQELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSRRSSQRAVLLVGLCDSGKTLLFVRLLTGLYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSARAIVFVVDSAAFQREVKDVAEFLYQVLIDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQLEKELNTLRVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSADIQDLEKWLAKIA
What is the function of this protein?
Component of the signal recognition particle (SRP) complex receptor (SR) (By similarity).  Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity).  May mediate the membrane association of SR (By similarity).
What are the official names of this protein?
Signal recognition particle receptor subunit beta, SR-beta, Protein APMCF1.
What is the protein family that this protein belongs to?
Belongs to the SRP receptor beta subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PSBK_GLOC7
Sequence: MDFALLLAKLPEAYQIFDPLVDVLPLIPLFFLLLAFVWQAAVGFK
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: BURP9_ORYSJ
Sequence: MKATGGPLPLILFLLIIIVLITAQHTAIAKPFFSLNAFAQGQPNDKDDQNMGKFYVYNKAQTNNYADQRMRKFYLYNKDQANDWDDQKMEKFYLYHEGKTNDRDDQKRKNIYLYNEGHANGDDQTMEKFYLFNKDQAKDGDDQKMGKFYLYNKDQANDWDDQKMERFYLYNKGHANEGDDQTMEKFYLYNKGHANEEDDQTMEKFYLYNKGQAKDGDDQKMEKNYLYNKDQANDWDDQKIEKFYLYHEGKANYRDDQNMEKFYLYKKGEEHKYIHSHGHGHVHFPEGAKDLYFFEDNLAPGSVLITRILSARQSSIFLHRNNSKHIPFSMKNITDILTMFSPVSATMADGIAATLQACEHTGMVHGEKAKCATSIESLLDVVVSSLGTKLVRALTPGAPMEGVPSLRYIVASATPVPNSQSMLACHDMLYPYKVFFCHTPKQTRLYQVSLVSGESGRPLIDGLLAVCHQNTSDWDTGHPFFHFMDVKPGETTACHFFGRGSIIWVPVPSVKEATQ
What are the official names of this protein?
BURP domain-containing protein 9, OsBURP09.
Protein: CYB_ASPME
Sequence: MPHHYILTLFGLLPVATNISTWWNFGSMLLTCLGLQVLTGFFLAVHYTANINLAFSSIVHISRDVPYGWMMQNLHAIGASMFFICIYIHIARGLYYGSYLNKETWMSGITLLITLMATAFFGYVLTWGQMSLWAATVITNLLTAVPYLGTSLTTWLWGGFAINDPTLTRFFALHFILPFAIISLSSLHIILLHEEGSSNPLGTNPDIDKIPFHPYHSHKDLLLLTLMIMSLFIISSFFPDIFNDPDNFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALVMSIMILFIIPFTHTARLRPMTFRPLSQLMFWTLVSTFITITWAATKPVEPPFIVISQVTSSLYFTFFLSTPILGWAENKMMNIS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MTC1_RHOHA
Sequence: MVVTSSAGCASRPRGRGRWPRLSRRSGCLEVPGRPRRPFLRPTVPGPTSARPRRGRAPHGRSTRCTGWRVQLSFSCPPFIKNRQFQFYLIRSPFSRVGYGLSDVNSSSLLGLWGIKFFACWENSNMIYIFKMLGYNQDKLPITSERLVPMASSISPEKLGAKIVEWYSCIVSREVEQAEEYKQEIGQLVNQLERSDEKVLSYYSLVLFRHQLLTEDVQQKRVEPTSLQAVNVEDTIYDGLLAFLYYFMSGQYEFYEGRYQSALRLYKIAEQKIDHVHDQSEKAEFYFRLGESYFAHHQYTFAVSYLEQAIDLFENNNFIWTILNCRLLLAAIKTELNLFDEAEKEYQSALADATPYPTTHALLLRALGLNRVRQRKLYEAEMYFAEALTIGDHSKSVEGLKTKANLANVRLRQNANNAEAIRLLQEAKAGATAIHLEECMVRCAITEALYINEGRDERLTSELQRLLEREFYTEYSELAEEIAEYYKQQSLLEKAFYYMKEALHYRTNMKMIGVEQQ
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-GATATC-3', methylates A-? on both strands, and protects the DNA from cleavage by the CeqI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.CeqI, M.CeqI, Adenine-specific methyltransferase CeqI, Modification methylase CeqI.
Protein: UREE_POLSJ
Sequence: MIQVSKVIPQGAGLAPVLVKRASTVELDWDVRQKSRFDATDSLGRTLGVFLPRGTLVRGGDVLVAEDGSMIKVIASPQPVLRITACSAHGSPFDLTRAAYHLGNRHVPIELKPDHLKIEPDHVLADMLRAMHLIVHEVEEAFEPEGGAYSAGGHGHGHDHGSHEHSAHDHGKHDHAPAKPATAATPAAHVHGPDCNHGHDHAHEAKPATIQIHKRRPDNL
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTB_ECO5T
Sequence: MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTSIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFVQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: IER2_RAT
Sequence: MEVQKEAQRIMTLSVWKMYHSRMQRGGLRLHRSLQLSLVMRSARELYLSAKVETHQPEFPPSRRALDPRLHPPREPEAAMEAATPDVEQPPEPMDTQEEVLRVQETPALCDPPPARVSRKRRSSSDLSDGSDAGLVPSKKARLEEVEGEATSEVSNRLQLPPAQTEGAFPNLARVLQRRFSSLLNCGPAVPPPTPPTCEAKPACRPADNMLNVLVRTVVAF
What is the function of this protein?
DNA-binding protein that seems to act as a transcription factor (By similarity).  Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (PubMed:17156131).  May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo (By similarity).  Promotes cell motility, seems to stimulate tumor metastasis (By similarity).
What are the official names of this protein?
Immediate early response gene 2 protein.
What is the protein family that this protein belongs to?
Belongs to the IER family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic during quiescence, translocates to the nucleus upon stimulation.
Protein: COOH_RHORU
Sequence: MSTYTIPVGPLHVALEEPMYFRIEVDGEKVVSVDITAGHVHRGIEYLATKRNIYQNIVLTERVCSLCSNSHPQTYCMALESITGMVVPPRAQYLRVIADETKRVASHMFNVAILAHIVGFDSLFMHVMEAREIMQDTKEAVFGNRMDIAAMAIGGVKYDLDKDGRDYFIGQLDKLEPTLRDEIIPLYQTNPSIVDRTRGIGVLSAADCVDYGLMGPVARGSGHAYDVRKQAPYAVYDRLDFEMALGEHGDVWSRAMVRWQEALTSIGLIRQCLRDMPDGPTKAGPVPPIPAGEAVAKTEAPRGELIYYLKTNGTDRPERLKWRVPTYMNWDALNVMMAGARISDIPLIVNSIDPCISCTER
What is the function of this protein?
The carbon monoxide dehydrogenase (CODH) oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (probably CooH).
What are the official names of this protein?
Carbon monoxide-induced hydrogenase.
What is the protein family that this protein belongs to?
To E.coli formate hydrogenlyase hydrogenase isozyme 3 and to bovine mitochondrial NADH-ubiquinone oxidoreductase.
Protein: KPYK_PYRAE
Sequence: MSAPRGDHAILRARNLTKRVATLGPSTDVLRPDELIKFLDLVDGVRINLAHASPNEVKFRIEAVRSYEKAKNRPLAVIVDLKGPSIRVGSTSPINVQEGEVVKFKLSDKSDGTYIPVPNKAFFSAVEQNDVILMLDGRLRLKVTNTGSDWIEAVAESSGVITGGKAIVVEGKDYDISTPAEEDVEALKAISPIRDNIDYVAISLAKSCKDVDSVRSLLTELGFQSQVAVKIETKGAVNNLEELVQCSDYVVVARGDLGLHYGLDALPIVQRRIVHTSLKYGKPIAVATQLLDSMQSSPIPTRAEINDVFTTASMGVDSLWLTNETASGKYPLAAVSWLSRILMNVEYQIPQSPLLQNSRDRFAKGLVELAQDLGANILVFSMSGTLARRIAKFRPRGVVYVGTPNVRVARSLSIVWALEPLYIPAENYEEGLEKLISLKGTTPFVATYGIRGGVHSVKVKL
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: RLMH_PELTS
Sequence: MFHITVLAVGRLKEKYLTEGAAEYLKRLSAYAKISVVEVEDGSLPENPAAAGGEKVKEKEGERLLGRLRPGTFLIALDVRGKMHSSEEMAEILNRLALSGRSDITFAIGGALGLSEKVLERAAMRLSFSRMTFPHQLVRLILLEQLYRWFKIARGEPYHY
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH_STRPQ
Sequence: MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEKTQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRINKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFISVRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQPAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_DICD3
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYDAIPRRAKEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGMTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRQEMSEFMTTSGFDYKMSAEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVRIPAEEVTVRFERGHPVALNGQTFSDDVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLVTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDPQALMLRDALQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGESVFSPDDRIGQLTMRNLDITDTREKLFNYVESGLIFSGNAGLPQVANPSLQDKSAK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.