PharMolix/UniProtQA huggingface dataset:
Protein: LEUC_SYMTH
Sequence: MGQGVIGMSGRTLLDKIWERHVVRREPGKPDLLYIDLHLVHEVTSPQAFEGLRMAGRRVRRPDLTIATMDHNVPTTDRSLPLTDEIAARQMAALERNCSEFGVRLFDLYSPFQGIVHVIGPELGLTQPGLTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQCLWQHKPKVMEIRVNGKLPPGTTAKDLILGIIGQIGTDGATGYVIEYTGEAIRSLSMEGRMTVCNMSIEAGARAGMIAPDETTFAYLKGRPHAPQGELWEAAVADWRTLASDPDAVYDRVVEFDAGQLAPVVSWGTNPGQVVPVTGRIPDPRDFADPAQRKAAEAALAYMDLEPGTPIQDIRIDRVFIGSCTNGRIEDLRAAAAVVKGRKVAPGVRAMVVPGSGQVKAQAEAEGLDQIFREAGFEWREAGCSMCLGMNPDILAPGERCASTSNRNFEGRQGKGGRTHLVSPAMAAAAAIAGHFVDVRELLAEGGAAR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: LOLD_PSYCK
Sequence: MSAILKATNINKIYDEGAVSTQVLTGLDLTVTAGERIAIVGTSGSGKSTLLHLLGGLDTPTSGEVWLHGQLLNSMNETERGAMRNKHLGFIYQFHHLLAEFTAIENVAMPLLMRPEVSTAEARQQAIDILNSVGLEHRLAHRPGELSGGERQRVAIARALVTKPSLILADEPTGNLDYDNAQSVFGLLSELQSTMQTALLMVTHDRNLAALADRQLLLRNGHWENY
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS13_FRAT1
Sequence: MARIAGVNIPVHKHTVIGLTSIYGIGKTRAQQICQTCNVDPTVKIKDLSEEQVESLRTEVAKFTVEGDLRREVSMDIKRLMDLGCFRGRRHRRSLPVRGQRTKTNARTRKGPRKPIKA
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: DDAD_ENTAG
Sequence: MHSVETFNLPALNSLLETTARRFGNRLAVQDDNGSLTFADFVEKVGILSAKLRLVIKRGEHVAVQLPRGINYIVAAYAIWEAGGVYLPLDNQWPSSRIEGILHRSHVRVLIHTSQADQGLELTELPAETRAESPVAGTPAYIIHTSGTTGEPKGVVVSHESLIHLVESHQRDIYQAYDVTEGPVAINASFCFDSALERMALVALGYSLHVVSDQVRKSPYELVKYLRDNSIVNVDLVPSHLKVLLSAGLNEKCDALRLVIVGGEAIDAELWREIVQNQAIYINVYGPTENTINTSFCEIRGETPHIGRPFKNVTCLLLNENGERCAAGEEGELLVAGRHLAQGYYNAPDLTDRVFVHIDGIRYYRTGDRVRQNEQGNLLYLGRIDDQVKINGFRIELADVQHNLTQLPGVKYAAVTPIKLPTGQGLLASIVWNSDAPEQTFSNLEALLGEKLPSYMVPTRWQKLDALPLTDNLKLDHKSLLSHWKNSQEQIGEKFAAESISATEHQIKNLWQKILRQPSLSPDAHFFASGGDSMAAMTLLVELKKVTPQDVSLGDIFKYPTIRKMAAWLDASSVQAES
What is the function of this protein?
Involved in dapdiamide antibiotics biosynthesis.  Activates and sequesters N-beta-fumaramoyl-DAP as a covalently tethered thioester for subsequent oxidative modification of the fumaramoyl group.
What are the official names of this protein?
Dapdiamide synthesis protein DdaD.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: EX7L_PSEFS
Sequence: MIKDPFARLGLDREILTVSQLNGRARVLLEDVFTNIWVEGEISNLARPASGHVYFTLKDSGAQVRCALFRNNAARVRQALKDGLAVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFDALKEKLSAEGLFSAERKVPLPAHPRRIGIISSPTGAVIRDIISVFRRRAPNIELTLIPTAVQGREAIPQIVRALKLADARGFDALILARGGGSLEDLWCFNEEAVARAVDACITPIVSAVGHETDVSISDFVADVRAPTPSAAAELLAPDASHLVRQVENLHRRLVMLMRNRLSHDRLRLEGMARRLRHPGERLRQQAQRLDDLDMRLRRAFERSLNTRRERLIRLETRLAGQHPGRQLALLRQRLESLAERLPRAMREGLKARRLQLQSQVQTLHVVSPLATLGRGYSILLDERGQAIRTAAQTHTGQRLTARLGEGQLQVRVEDNHLTPVTLSLLD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCGI_ECOLI
Sequence: MNTIHLRCLFRMNPLVWCLRADVAAELRSLRRYYHLSNGMESKSVDTRSIYRELGATLSYNMRLGNGMEXEPWLKAAVRKEFVDDNRVKVNNDGNFVNDLSGRRGIYQAAIKASFSSTFSGHLGVGYSHGAGVESPWNAVAGVNWSF
What are the official names of this protein?
Putative uncharacterized protein YcgI.
Protein: SMRD1_BOVIN
Sequence: MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPRPGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSLKRPAPQQIKQVQQQAVQNRNHNAKKKKMADKILPQRIRELVPESQDYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEPIIINHVISVDPNDQKKTACYDIDEEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKVMTDVVGNSEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT
What is the function of this protein?
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).  Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (By similarity).  Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex).  During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.  The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.  As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF).  The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.  The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).  Has a strong influence on vitamin D-mediated transcriptional activity from an enhancer vitamin D receptor element (VDRE).  May be a link between mammalian SWI-SNF-like chromatin remodeling complexes and the vitamin D receptor (VDR) heterodimer.  Mediates critical interactions between nuclear receptors and the BRG1/SMARCA4 chromatin-remodeling complex for transactivation (By similarity).  Interacts with AKIRIN2 (By similarity).
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, 60 kDa BRG-1/Brm-associated factor subunit A, BRG1-associated factor 60A, BAF60A, SWI/SNF complex 60 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SMARCD family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MABA_MYCAV
Sequence: MTDTATENTTESAADYGRPAFVSRSVLVTGGNRGIGLAIAQRLAAEAHKVAVTHRGSGAPDGLFGVECDVTDNDAVDRAFTEVEEHQGPVEVLVSNAGISKDAFLIRMTEERFTEVINANLTGAFRVTQRAARSMQKKRFGRIIYIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELSKAGVTANVVAPGYIDTEMTRALDERIQAGALEFIPAKRVGTAAEVPGAVSFLASEDASYIAGAVIPVDGGMGMGH
What is the function of this protein?
Part of the mycobacterial fatty acid elongation system FAS-II, which is involved in mycolic acid biosynthesis.  Catalyzes the NADPH-dependent reduction of beta-ketoacyl derivatives, the second step of the FAS-II elongation cycle.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase MabA, 3-ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase, Beta-ketoacyl-acyl carrier protein reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: TIG_AGRRK
Sequence: MQVIETLAEGLKREIKVVISAKDMEGRMNERLAEVKDKVRINGFRPGKVPVSHLKKVYGKSIMADLVNEIVRDQPPAILTERGEKSATQPEVAMTEDKDEAEKILAAEADFEFTLSYEVIPAIELKSVKGVKVTREVAEIGEDEVTEQILKIAESARSYEAKKGKAADGDRVTIDYLGKVDGVAFDGGKDEDSQLVIGSNRFIPGFEEQLVGVKAGDEKTITVTFPAEYPAKNLAGKEATFDITVKEVAAPGEVEINDELASKLGLESADRLKEIVRGQIESQYGSVTRQKVKRQILDQLDEMYQFDTPQKLVDAEFASIWRQIQTDLAESGKTFEDEDTTEEKAREEYRKLAERRVRLGLVLSEIGEKAGVEVSEDELQRALYAQLQQFPGQEKEILDFFRNTPGASANLRAPIFEEKVIDHLLTEVDVTDKTVSKEALLADDESEDKPAAKKAAPKKKAAKAEATEAAAEGEEAAVPKKKAAPKKKAAEDSAE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RB40A_HUMAN
Sequence: MSAPGSPDQAYDFLLKFLLVGDRDVGKSEILESLQDGAAESPYSHLGGIDYKTTTILLDGQRVKLKLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDRWIKKIEEHAPGVPKILVGNRLHLAFKRQVPREQAQAYAERLGVTFFEVSPLCNFNIIESFTELARIVLLRHRMNWLGRPSKVLSLQDLCCRTIVSCTPVHLVDKLPLPSTLRSHLKSFSMAKGLNARMMRGLSYSLTTSSTHKSSLCKVEIVCPPQSPPKNCTRNSCKIS
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ras-related protein Rab-40A, SOCS box-containing protein RAR2A, Protein Rar-2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: CDR_STAAT
Sequence: MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRRYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVSVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEINAINGNEITFKSGKVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK
What is the function of this protein?
Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide.
What are the official names of this protein?
Coenzyme A disulfide reductase, CoA-disulfide reductase, CoADR.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.
Protein: ARLY_STAAS
Sequence: MSNKAWGGRFEVQPEEWVDDFNASITFDQTLINQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TREF_SALHS
Sequence: MLNQKLNPTPSEDLTIDVDLLYETDPCELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSTKLFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRRFVENHFWLPETLSSEYVSNPENSLKEHIDQLWPILTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLALNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDAGRLASIRTTQFIPIDLNAFLYKLESAIANISALKGERDTEALFRQKASDRRAAVNHYLWDDENGCYRDYDWRREEMALFSAASIVPLYVGMANHEQADRLANVVRSRLLTPGGIMATEYETGEQWDKPNGWAPLQWMAIQGFKRYGDDMLGDEIAHNWLKTVNHFYQEHHKLIEKYHISGGTPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_LACLS
Sequence: MSTLLLEAAPNTVLGNIIVVSGAFIILLVLLRLFAWNAITSVFASRAKKISDDIDAAEANNKQAADLVKQRQAELAGSKEEAANIIQVANDTASQNRAKVLATANEEATSLKKRAQEDIEQERKEALNTVKGDVADISVQIAEKLIGQSLDASAQQELIDSYLAKLGE
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YFCD_SALTI
Sequence: MVEQRRLASTEWVDIVNEDNEVIAQSSREQMRAQRLRHRATYIVVHDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFAEHGLFYFEDQHCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLKALALWMTRNAKNEAALQEKPEETE
What are the official names of this protein?
Uncharacterized Nudix hydrolase YfcD.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: TMM25_MOUSE
Sequence: MELPLSQATLRHTLLLLPALLSSGQGELAPQIDGQTWAERALRENEHHAFTCRVAGGSATPRLAWYLDGQLQEATTSRLLSVGGDAFSGGTSTFTVTAQRSQHELNCSLQDPGSGRPANASVILNVQFKPEIAQVGAKYQEAQGPGLLVVLFALVRANPPANVTWIDQDGPVTVNASDFLVLDAQNYPWLTNHTVQLQLRSLAHNLSVVATNDVGVTSASLPAPGLLATRIEVPLLGIVVAGGLALGTLVGFSTLVACLVCRKEKKTKGPSRRPSLISSDSNNLKLNNVRLPRENMSLPSNLQLNDLTPDLRGKATERPMAQHSSRPELLEAEPGGLLTSRGFIRLPMLGYIYRVSSVSSDEIWL
What is the function of this protein?
In neurons, modulates the degradation of NMDA receptor GRIN2B subunit.  Plays a role in the regulation of neuronal excitability.
What are the official names of this protein?
Transmembrane protein 25.
What are the subcellular locations of this protein?
Late endosome. Lysosome. SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: PME3_SOLLC
Sequence: MATPLQPFLTKTHKQNPIIGFNILTFVVTLFVALFLVVFLVAPYQFEIKHSNLCKTAQDSQLCLSYVSEIVTTESDGVTVLKKFLVKYVHQMNNAIPVVRKIKNQINDIRQQGALTDCLELLDQSVDLVSDSIAAIDKRSRSEHANAQSWLSGVLTNHVTCLDELTSFSLSTKNGTVLDELITRAKVALAMLASVTTPNDEVLRQGLGKMPYWVSSRDRKLMESSGKDIIANRVVAQDGTGDYQTLAEAVAAAPDKNKTRYVIYVKMGIYKENVVVTKKKMNLMIVGDGMNATIITGSLNVVDGSTFPSNTLAAVGQGFILQDICIQNTAGPEKDQAVALRVGADMSVINRCRIDAYQDTLYAHSQRQFYRDSYVTGTVDFIFGNAAVVFQKCQIVARKPNKRQKNMVTAQGRTDPNQATGTSIQFCDIIASPDLEPVMNEYKTYLGRPWKKHSRTVVMQSYLDGHIDPSGWFEWRGDFALKTLYYGEFMNNGPGAGTSKRVKWPGYHVITDPNEAMPFTVAELIQGGSWLNSTSVAYVEGLVE
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Pectinesterase 3, PE 3, Pectin methylesterase 3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RL14E_THEPD
Sequence: MKVYDVGRICVKTSGREAGLKCVIVDIIDDNFVLVTGPKSVSGVKRRRANIRHLEPLEYKISISKGASDEEVKAALEKAGLIEFMKEKVKPTVSTTFV
What are the official names of this protein?
50S ribosomal protein L14e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
Protein: RS18_VESOH
Sequence: MAKQIKRKRRPQIKINTFCRFTAAGVTKIDYKDIDILLKNIDESGKITPSRMTGTSAKFQRKLTTAIKRARFLALIPYTDKHKK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ALR_HELAH
Sequence: MLRRASFVEVDTSSLRHNFHAAKNAIPKDAHIMAVVKANAYGVGALKASEVFLQEGAHYLGVATLDEALELRSCFPKTPILILGYSPNSNAQMLIDNNLTAMIFSLEQAGVFSQAALKSQKHLKVHLKIDTGMHRLGLEPNFKSIEMIKKIRALNGLEVEGIFTHLSNANANIKTHAKNQMKIFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNNNENRFLNLYRPGIMLYGFYPSNEMKQSCQTILNNVVSLKAKIVQIKRVKKGEFVGYGKHFYTNEETLIGTLALGYADGLVRDLGNRIQVAINNQLAPLIGKVCMDQCFVKLDGIEAKEGDEVILFGDKSTKANDANEIAMLLNTIPYETISTLSKRLERVYV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: IOVO_OPIHO
Sequence: TATVDCSDYPKPACLLEYMPLCGSDNKTYDNKCSFCNAVVDSNGTLSLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: COX2_DRONO
Sequence: AICSLVLYLLTLMLMEKLSSNTVDAQEVELIWTILPAIVLILLALPSLQILYMMDEIDEPDLTLKAIGHQWYWTYEYTDFKDLSFDSYMVPTSELPSGHFRLLEVDHRVVVPMESPIRVIITAGDVLHSWAVPTLGVKTDAIPGRLNQTSFITTRPGIFYGQCSEICGANHSYMPIVVESTPLTHFENWSSLLSASSSL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FDHC_METTF
Sequence: MGSSFKSPADTAKACSAIAELKEKAPLGKVIVLSFLAGAYIAFGGLLAEVVTGGMAKAGYPAGLVKLVFGAVFPVGLMLVVIAGSELFTGNCMYMPLGILDKRASIMGLIRNWVTSWVFNLVGAVFVAYFLAVATGILTADPWQAGALTVAKTKALGGASFIAAGKVTKSLTWAQAFWRAVGCNWLVCLAVYLAIASDDIIGKIWGIWFPIFAFVAIGFEHSVANMFFIPVGIFLGGVTWSQFFMNNLIPVTLGNIVGGAIFVACLYWYTYLKE
What is the function of this protein?
May act as a formate transporter.
What are the official names of this protein?
Probable formate transporter.
What is the protein family that this protein belongs to?
Belongs to the FNT transporter (TC 2.A.44) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DHRS4_PIG
Sequence: MRAAGQLLRACSQTWKSVRMASTGVERRKPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGETVVVGGGTASRL
What is the function of this protein?
NADPH-dependent oxidoreductase which catalyzes the reduction of a variety of compounds bearing carbonyl groups including ketosteroids, alpha-dicarbonyl compounds, aldehydes, aromatic ketones and quinones (PubMed:12604222, PubMed:19056333).  Reduces all-trans-retinal and 9-cis retinal (Probable).  Reduces 3-ketosteroids and benzil into 3alpha-hydroxysteroids and S-benzoin, respectively, in contrast to the stereoselectivity of primates DHRS4s which produce 3beta-hydroxysteroids and R-benzoin (PubMed:19056333).  In the reverse reaction, catalyzes the NADP-dependent oxidation of 3alpha-hydroxysteroids and alcohol, but with much lower efficiency (PubMed:19056333).  Involved in the metabolism of 3alpha-hydroxysteroids, retinoid, isatin and xenobiotic carbonyl compounds (PubMed:12604222, PubMed:19056333).
What are the official names of this protein?
Dehydrogenase/reductase SDR family member 4, NADPH-dependent carbonyl reductase, CR, PHCR, NADPH-dependent retinol dehydrogenase/reductase, NDRD, Peroxisomal carbonyl reductase, PerCR, Peroxisomal short-chain alcohol dehydrogenase, PSCD, Short chain dehydrogenase/reductase family 25C member 2, Protein SDR25C2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: NCAP_CVCAI
Sequence: MASQGQRVSWGDESTKRRGRSNSRGRKNNDIPLSFFNPITLEQGSKFWDLCPRDFVPKGIGNKDQQIGYWNRQTRYRMVKGRRKNLPEKWFFYYLGTGPHADAKFKQKLDGVVWVARGDSMTKPTTLGTRGTNNESKALKFDVKVPSEFHLEVNQLRDNSRSRSQSRSQSRNRSQSRGRQLSNNKKDDNVEQAVLAALKKLGVDTEKQQRSRSKSKERSSSKTRDTTPKNENKHTWKRTAGKGDVTKFYGARSSSANFGDSDLVANGNGAKHYPQLAECVPSVSSILFGSHWTAKEDGDQIEVTFTHKYHLPKDDPKTGQFLQQINAYARPSEVAKEQRQRKARSKSVERVEQEVVPDALTENYTDVFDDTQVEIIDEVTN
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the alphacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: YNAG_LYSSH
Sequence: MMNTYFQQVNRYLTMVAQQESEQINRVAQLIVKRLVQGGIIQLFGSGHSMLLAQECYFRAGGLVPVKPIHIESLMLHQGARQSSQNEKKQAFLAPYKDELQFDDKDVCIIISTSANNPVPIDMAIYAKEAGAHTISLQSLAYQQQPSRHPSGQRLEDIADDVLNTHVPLGDGVLTVDEFQYGPVSTVLGAALLNALCAQIIEILHEQGASLPVFASSNLGNTNNDELIDQYGQRDSFLRP
What are the official names of this protein?
UPF0309 protein in nagA 3'region, Orf2.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.