PharMolix/UniProtQA huggingface dataset:
Protein: NODZ_SINFN
Sequence: MYNRYVLSRRRTGFGDCLWSLAAAWRYAQRTARTLAVDWRGSCYLDQPFTNAFPVFFEPIKDIAGVPFICDNRVNEFSFPGPFFPNWWNKPAIECVYRPDAQVFRERDELDELFQAQDDVEANTVVCDACLMWRCDEEAERQIFCSVKPRAEIQARIDAIYQEHFYGYSAIGVHVRHGNGEDVMDHAPYWADPDLAVHQVCTAINAAKALPHPKPVRVILCTDSARVLDQVSSRFPDLLTIPKSFRADQSGPLHSADLGVEGGISALVEMYLLGLCDTVIRFPPTSAFTRYARLSVPRVIEFDLNDPSRLVVIERSSTNTAS
What is the function of this protein?
Fucosyltransferase which adds the fucose moiety of the nod factor on its terminal reducing N-acetylglucosamine end.  Uses GDP-fucose as the donor group.
What are the official names of this protein?
Nodulation protein Z.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 23 family.
Protein: UREG_PARDP
Sequence: MSNGPLRVGIGGPVGAGKTTLTEQIARALAPRLSMAVITNDIYTREDAEALMRAQVLPSERIRGVETGGCPHTAIREDASINLAAIAELNAAFPDLDLVLIESGGDNLAATFSPELADLTIYVIDTAAGQDIPRKRGPGLARSDLLVVNKTDLAPHVGVDAALLEADARASRAGRPVVMAALRHGKGVAEVVDFLIEQGGLQPCPAHSHGQ
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_NEIG1
Sequence: MKPSILEKLQQLGDRLEEVTHLLGQPEATSDMDNYRKLTREHAELTPVVEVFQNYRLAQSDLADAEEMLSDPEMKDFAAEEIEAAKAKIDELDTELQKLLLPKDADDDKNIFIEIRAGTGGDEAALFAGDLLRMYSRYAERNRWQVEIVSANESELGGYKEVIARIVGLGAYSRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPEADELEDIELNPADLRTDTFRASGAGGQHINKTDSAVRITHLPTGMVVECQDGRSQHANKAQAMKVLAARLNDAQKREVQAKEAAERKSLIGSGDRSERIRTYNYPQGRVTDHRINLTLHKLDFVMDGDLAEITDALIAEHQAELLAAMGD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR14_BIGNA
Sequence: MAKKGMLEREKKRQNLVYKYNSRRQALKNSIKYSSSFSETSLLKKELEKLPLNSMKIRLRNRCFVTGKPRGFYRNFGLSRNMLRYMGHECLIPGLMKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HRCA_CHLCV
Sequence: MSRSWISKRESKILYILLTTTELYLKTGHPVGSKTLKEYEGSNLSTATIRNYFSELEAEGFLKKNHISGGRIPTDLAFRYYVDHCADCSQDELPESTINLLNQLPEESQNIVKDLQKASELLGEALQLPTCFSSPRFDNDSVTNIQLSLVDEQRAVVILSTEFGQIFTDTLWLSEASNPASLKRIEIFLQSYVRKQSPMEILSQKEEDIGMTLYNEVVVRYLTRYCNFSEEDLYQTGLSKLLRYESFKDPDMLALGLSFFENRRHMCKLLDIGMHRDRPTAFIGNELSDIFRTPNPQCAVITIPYYMNRTPLGAFGVLGPVNLPYKEIFKTLTIFADKIKASLTQSFYKFKLSFRRPCPSDPTLSKEPTLLARYSSIKLLPPKETS
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: POPB_GALM3
Sequence: MSSVTWAPGNYPSTRRSDHVDTYQSASKGEVPVPDPYQWLEESTDEVDKWTTAQADLAQSYLDQNADIQKLAEKFRASRNYAKFSAPTLLDDGHWYWFYNRGLQSQSVLYRSKEPALPDFSKGDDNVGDVFFDPNVLAADGSAGMVLCKFSPDGKFFAYAVSHLGGDYSTIYVRSTSSPLSQASVAQGVDGRLSDEVKWFKFSTIIWTKDSKGFLYQRYPARERHEGTRSDRNAMMCYHKVGTTQEEDIIVYQDNEHPEWIYGADTSEDGKYLYLYQFKDTSKKNLLWVAELDEDGVKSGIHWRKVVNEYAADYNIITNHGSLVYIKTNLNAPQYKVITIDLSKDEPEIRDFIPEEKDAKLAQVNCANEEYFVAIYKRNVKDEIYLYSKAGVQLTRLAPDFVGAASIANRQKQTHFFLTLSGFNTPGTIARYDFTAPETQRFSILRTTKVNELDPDDFESTQVWYESKDGTKIPMFIVRHKSTKFDGTAAAIQYGYGGFATSADPFFSPIILTFLQTYGAIFAVPSIRGGGEFGEEWHKGGRRETKVNTFDDFIAAAQFLVKNKYAAPGKVAINGASNGGLLVMGSIVRAPEGTFGAAVPEGGVADLLKFHKFTGGQAWISEYGNPSIPEEFDYIYPLSPVHNVRTDKVMPATLITVNIGDGRVVPMHSFKFIATLQHNVPQNPHPLLIKIDKSWLGHGMGKPTDKNVKDAADKWGFIARALGLELKTVE
What is the function of this protein?
Dual function macrocyclase-peptidase involved in the biosynthesis of the highly toxic amanitin toxin family of macrocycles (PubMed:22202811, PubMed:28866879, PubMed:29051530).  Cleaves peptide bonds on the C-terminal side of prolyl residues (PubMed:29051530).  The enzyme first removes 10 residues from the N-terminus of a 35-residue substrate (PubMed:29051530).  Conformational trapping of the 25 amino-acid peptide forces the enzyme to release this intermediate rather than proceed to macrocyclization (PubMed:29051530).  The enzyme rebinds the 25 amino-acid peptide in a different conformation and catalyzes macrocyclization of the N-terminal eight residues (PubMed:28866879, PubMed:29051530).
What are the official names of this protein?
Dual function macrocyclase-peptidase POPB, Prolyl oligopeptidase B, POP B, Toxin-processing prolyl oligopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9A family.
Protein: Y5168_ARATH
Sequence: MMACCLRNKRRMKGKLSWKSKKRDLSHSGNWAPEDDNDEGKIVFFGGSNYTFDLDDLLAASAEILGKGAHVTTYKVAVEDTATVVVKRLEEVVVGRREFEQQMEIVGRIRHDNVAELKAYYYSKIDKLAVYSYYSQGNLFEMLHGKLSFCIPLSMLLWYAVSKTNNSTFAGESQVPLDWESRLRIAIGAARGLAIIHEADDGKFVHGNIKSSNIFTNSKCYGCICDLGLTHITKSLPQTTLRSSGYHAPEITDTRKSTQFSDVYSFGVVLLELLTGKSPASPLSLDENMDLASWIRSVVSKEWTGEVFDNELMMQMGIEEELVEMLQIGLACVALKPQDRPHITHIVKLIQDIPTNFNL
What are the official names of this protein?
Probably inactive receptor-like protein kinase At5g41680.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: ISPT_BORPA
Sequence: MALSSTQAIPETGDIPRHVAIIMDGNGRWATRRHLPRTAGHAKGVHAVRRVVEACGRRGVRYLTLFAFSSENWRRPADEVSLLMRLFVQALEREVDKLQDQGVRLHVVGDLSAFEPKLQELIAQAQERTEHNDRLHLTVAANYGGRWDILQATRAMLRADPGLAQDPDRIDEARLAEHLSMAWAPEPDLFIRTGGEQRISNFLVWQLAYAEFYFTEQFWPDFGADELDAAFEWYRTRERRFGRTSAQLRGGAKR
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: FA78B_MOUSE
Sequence: MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK
What are the official names of this protein?
Protein FAM78B.
What is the protein family that this protein belongs to?
Belongs to the FAM78 family.
Protein: MATK_PINEG
Sequence: MDEFHRCGKEDSFWQQCFLYPLFFQEDLYAISHDHYLDVSSSSRPMEHLSSNDQLSFLTVKRLIGQIRQQNHSIVLFVNCDPNPLADRKKSFYSESVLEALTLVLEVPFSIWSKYSVEGMNESKSFRSIHSIFPFLEDKFPHSNSILDARIPYSIHPEILVRTFRRWIRDAPSLHPLRSVLYEYRNSPDNLQRSIIVVPRVNTRFFLFLWNYYVCECESILFSRLKRSSHSRSLSHGSFPQRTHFHRKIKHIIIFSRRNSLKSIWSLKDPKIHYVRYGERPIIAIKGAHLLVKKCRYYLLIFRQFYFHLWSEPYRVCSHQLSKNCSSSPGYFLRVRMNPILVRTKMLDELFIADLITDEIDPIVPIVPIIGLLATEKFCDISGRPISKLSWTSLTDDDILDRFDQIWRNLFHYYSGSFDRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFKKSFSKEREFYSLRFSSKAAARSQRERIWHSDIPQINPLANSWQKIQDLKIENLFDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFTS_SYNR3
Sequence: MAEISAKLVKELRDQTGAGMMDCKKALNETSGDLTKATEWLRQKGIASAEKKAGRTAAEGAVGSYIHTGARVGVLVEVNCETDFVARGDAFQELVRNVAMQIAACPNVEFVTTDDIPADVKERETNIEMGRDDLGNKPEAMKAKIVEGRVNKRLKELALLEQPFIKDSSLSVAEMVKQLAGKIGENIQVRRFTRYTLGEGIEVKQEDFAAEVAAMTA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_BURM7
Sequence: MENTQENPTDQTTEETGREAQAAEPAAQAAENAAPAAEAALAEAQAKIAELQESFLRAKAETENVRRRAQDDVAKAHKFAIEGFAENLLPVLDSLEAAVGDTSGDLAKVREGVELTLRQLTSALEKGRVAALNPVGEKFDPHLHQAISMVPADQEPNTVVAVLQKGYTIADRVLRPALVTVAQPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNB_SALTY
Sequence: MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTELYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRIRTGEEDDAAI
What is the function of this protein?
P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of GlnA.  When P-II is uridylylated to P-II-UMP, these events are reversed.  When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity).
What are the official names of this protein?
Nitrogen regulatory protein P-II 1.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: FFSR_ASPFV
Sequence: MDTLTAPTTQSEQPPPPLTASLSRRYACDRCRSHKLRCNRDLMTSTNSPCQRCRKARVKCTIGASIRVGLSPEELKNGENVHRASPGRSAGSHRTASTPSNHAPRSHGRTFTPESAHQAPPYPSNRSMSGSMRLSPVPWLDMISFDGAQELNFDGSTSGLPMGSHTNGSGPLHAPMGGSTSSNTSSTFLDVRPPLHTPASSKPQQEAWRTGDDSTDLRLLSQIPRTRGGGVTDPAAGLTQQHPAGVTSSAPLVSHDHAFAPPQTSIISEPIPGDDLPAGGRPPTWFPARSRAGSTPSPTELKDACIQKLSDLSASLMKDLDLIITCKTASSFLFTPSDKTAAGYLFKTLDGSMTEDNAVARMLYGSERFLDIIKLFNQLPSLPSSSLSMPAAAAAAAAAASYGSTRPVDSDDAYYYSDLEDTGDIRSRNPTPEDRGNEQWSILQAYLGRAGQGPPMGPSQGSSSRSTTTNCSSSFVEVQKPDVPSILVILSCYTCLLKIYETVFFVIQHVLECSPANPSGTTDIPHTVRDLNINGFFLQNHRTLQIKILIQVSTYMLDSIQKSLGTILSDSMFQALLKTLMKEEGCTITSQGEETGMQGVRDLIRRVEEMLA
What is the function of this protein?
Transcription factor that specifically regulates the expression of the gene cluster that mediates the biosynthesis of the cytotoxic leucine-containing cytochalasans, including aspochalasin C, aspochalasin E, TMC-169, flavichalasine F, aspergillin PZ, aspochalasin M and flavichalasine G.
What are the official names of this protein?
Transcription factor ffsR, Cytochalasans biosynthesis cluster protein ffsR.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPX2_SYNY3
Sequence: MPLPTSLTTLDGTPLAPEVIADKVVLFVNVASKCGLTPQYSGLVALDKAYGEKGLVIIGVPCNQFGAQEPGSPEEIKDFTKTKYDVDFTLLEKQDVNGPNRSPLYQFLVGDGEDISWNFGKFLIGRDGQVVARFDPQTKPDDTNLKAAIEKALG
What is the function of this protein?
Hydroperoxy fatty acid reductase essential for the removal of lipid hydroperoxides under normal and stress conditions, leading to the protection of membrane integrity.
What are the official names of this protein?
Hydroperoxy fatty acid reductase Gpx2.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: GLNE_ECOBW
Sequence: MKPLSSPLQQYWQTVVERLPEPLAEESLSAQAKSVLTFSDFVQDSVIAHPEWLTELESQPPQADEWQHYAAWLQEALCNVSDEAGLMRELRLFRRRIMVRIAWAQTLALVTEESILQQLSYLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGFVYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLSAIAELHLLSENDAEQLRVAYLFLRRLENLLQSINDEQTQTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSEQWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLMPHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIASQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQLTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHLALQELPGHVSEDCFTAERELVRASWQKWLVEE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: GLPE_HAEI8
Sequence: MSFKEITPQQAWEMMQQGAILVDIRDNMRFAYSHPKGAFHLTNQSFLQFEELADFDSPIIVSCYHGVSSRNVATFLVEQGYKNVFSMIGGFDGWCRAELPIDTTY
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_GLOC7
Sequence: MSAATDEILEKLKSLSLLEAAELVKQIEETFGVSAAAPVGGMMMAAPGAVPGAAAEPEEEKTEFDVILEEVPADKKIAILKVVRTITGLGLKEAKDLVESTPKPIKEGTNKDDAEETKKKLEEAGAKVTVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: MNS1B_NEOFI
Sequence: MHLPSLSVALALVSSSLALPQTVLPESDVSSHAAAVKEAFSHAWDGYMKYAFPHDELLPISNSYGDSRNGWGASAVDALSTAIVMRNATIVNQILDHIAKIDYSKTSDTVSLFETTIRYLGGMLSGYDLLKGPAADLVKDSTKVDMLLQQSKNLGDVLKFAFDTPSGVPYNNINITSHGNDGATTNGLAVTGTLVLEWTRLSDLTGDQEYAKLSQRAESYLLAPQPSSGEPFPGLVGSEISIQTGQFTNGFVSWNGGSDSFYEYLMKMYVYDPKRFATYKDRWVAAAESSIDHLASSPASRPDLTFLATYNKGSLGLSSQHLACFDGGSYLLGGTVLDRADLIDFGLKLVDGCAETYHQTLTGIGPESFGWDEKSVPADQKEFYERAGFYVQSGAYILRPEVIESFYYAYRVTGKKQYRDWVWNAFVNINKYCRTGSGFAGLTDVNAVNGGNRYDNQESFLFAEVMKYAYLTHAPGMSPISIADEDKANESRG
What is the function of this protein?
Involved in the maturation of Asn-linked oligosaccharides.  Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2) (By similarity).
What are the official names of this protein?
Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B, Class I alpha-mannosidase 1B, Man(9)-alpha-mannosidase 1B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle lumen.
Protein: RSC9_YEAST
Sequence: MNSLASNTPLNGTPVSEAPATSSEPVNMFETMVANPIKVSRLQSNGVLTGPAANTKSIHYSLANFNVFQSLPKETARGVDDLTRMEMALLSGIPEEIKWSLKKYLTYSNKAPYMISLRTLPDLLPLFKTFILPLERIVEGLNKSSICDSKAMDSLQMGLNALLILRNLAQDTDSVQILVKDREIKSFILFILKKFQCVATGDNKWQLYEGNATFFNELTHYTLDLMEAISSYIAPAMKDDHYFQTLVSILNYTKDRYMVISILRSLSRLLVRSKANEESAADNLDHKTLSLIVSFLLLECDSELIIASLDFLYQYILPGSQRITELFKSKECSLILEATLPNLLSYNIATPDYHLLQKHKIRLIKRLKPPAPKEPPNLSEDLFQQLFKLNEPLRSTAWLRCCFEPVQEAEFTQISLWRSYESKFGQPVRESGRKLLPAVEFIKNVSNAFNNAAAIVITDPVTGKKRFVIKGIQPRFKALGIADGERESQVPISALKSKFLNDSKEITPARQNSIPEVKFPQELSDVSKVACTFLCLLSNDTDDGAGSAFCQRIRPLVLHKLADIPPLTLALSEYMENTSGL
What is the function of this protein?
Component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning.  RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA.  The reaction requires ATP and involves an activated RSC-nucleosome intermediate.  Remodeling reaction also involves DNA translocation, DNA twist and conformational change.  As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton.  This subunit plays a role in transcriptional response to stress.  It is involved in both repression and activation of mRNAs regulated by the target of rapamycin (TOR) kinases, and in the synthesis of rRNA.
What are the official names of this protein?
Chromatin structure-remodeling complex subunit RSC9, RSC complex subunit RSC9, Remodel the structure of chromatin complex subunit 9.
What is the protein family that this protein belongs to?
Belongs to the RSC9 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to centromeric and flanking chromatin. Association with these loci is dependent on STH1.
Protein: BSHC_KORVE
Sequence: MIPDCIPLAEVPHTTRLFADYLAHSAKLQAFYPALKYNQNLAAYTSSIQYQPGTRDRVATALQILNERLGASPEALANIERLRRGAYAVVSGQQVGLFGGPLLAVLKAAHAVRLARDLTAQGTDTIPVFWMASEDHDLAEVDHVFLPKNDFSLQRFTADATGTTGAPMSDLRFEPTIENLVQQTSELLGDSSLVDILRESYRPGETVAGAFGKLFARLFAKHGLVLLDPADTELHRIAAPLFRRAVAEAAEIARALVDRGKELEHAGYHEQVKVSASSVLLFGIQDGARVAIQRQNDHFSVGKEKLTQEELLARIDAEPEKFNANVLLRPVMQDTLLPTLAYIGGPAEVAYFAQGSVVYERLLGRATPILPRFSATLIEPKVEKLLEKYDLKFEDINHGADALAEKLAQKTLPPELDEQFRVALATVTQTMAQAKDALAKVDASLVEAAERATSKMRYQVGRLHRRAARAALRRTHVLSQHADLIVNALYPEKELQERTVGAAYFLAKYGLDLVDTLVDAAGTCPEHRVIRV
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: BIOB_FRASN
Sequence: MTAPVTAPTTMPAQTPPTVETDVVTEAPRPLDDDILARARRQVLDEGRGLDEQDVLAVLQLPDEALGDLLALAHEVRLRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGRFDSPVRSAWLDVPSLVEAAKATAATGATEFCIVAAVRGPDQRLMAQIREGVAAIREAVDINVACSLGMLTQEQVDELAGLGVHRYNHNLETARSHFPKVVTTHSWEERWETCELVRAAGMELCCGAIIGVGESLEQRAELAAQLAALEPDEVPLNFLNPRPGTPFGDLPAVDSREALRTIAAFRLALPRTILRYAGGREITLGDLDVQGMLGGINAVIVGNYLTTLGKNPESDLAMLTELRMPIKSLQATL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: TUSD_ECOSM
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHELSCVFFYREGVYNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGIVDETEAGRLGLASSNLQSGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_SALPC
Sequence: MSEPTSRRPAYARLLDRAVRILAVRDHSEQELRRKLSAPVMGKNGPEEIDATADDYERVIAWCHEHHYLDDERFVMRFIASRSRKGYGPARIYQELNQKGISRESTEKAMRECEIDWSEMAHEQAVRKYGEPLPSNFSEKVKVQRFLLYRGYLMDDIQQIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHC_NOCSJ
Sequence: MALHDTPSARKVTTTPDGPARLYVCGITPYDATHLGHASTYVAFDLLNRAWRNAGHDVTYVQNVTDVDDPLLERAAKVHVDWVELAERETELFRQDMAALRVIPPDHYVGAVESIPLVIELIGRLETAGAIYRVEDDLYFSVTADPAFGAESGWDRERMLEIYPERGGDPDRPGKKDPLDCVVWRGRREGEPSWESPWGPGRPGWHVECTAIAQRHLGGAFDVQGGGSDLVFPHHEMCAGHAQVAVPGTPFAQVYSHGGMVGYDGEKMSKSRGNLVFVSALRNSDVDPMAIRLALLRHHFRSDWEWTDDQLWVAVDDIARWRKALSLGAGAPAAPVIDEVLAALADDLDAPRATAAIDRWVAATLGTAGLADTTDPDAAARLLAALDAALGLALWLS
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: ENO_GLUOX
Sequence: MSAIVDITSREILDSRGNPTVEVEVELSSGARGRAAVPSGASTGAHEAVELRDGDKSRYGGKGVLKACSHVENDILEVLQGAESEDQIAIDNAMIDLDGTPNKSRLGANAILGVSLAVAKATAEELELPLYRYVGGAYAHLLPVPMMNIVNGGEHADNPIDIQEFMIQPVGAPTVADAIRMGSEIFARLKKGLSEAGYNTNVGDEGGFAPNLKSADEALGFIAKSVEAAGYKLGEDVTFALDCAATEFYADGRYNLKGEGKEFDASGMISYLEDLANRYPIVSIEDGLAEDDWEGWAELTTRLGKKLQLVGDDLFVTNPERLRRGIKAGTGNALLVKVNQIGTLTETLEAVETAHKAGYACVMSHRSGETEDSVIADLAVATNCGQIKTGSLSRSDRTAKYNQLIRIEQQLGSAARYAGRSILKNS
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: UREE_UREU1
Sequence: MTVFKEILGNITDIENVESYQIENIHLTSDDVLKRVIIISSDQNVEYGIRLEEDKKLRDGDILYKDDYKLVVIRLELSDVLIITARTIGEMAQIAHNLGNRHMPAQFTETQMIVPYDYLVEQYLQDNKALYEREKIKLKEAFRHCSDAK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.