PharMolix/UniProtQA huggingface dataset:
Protein: STX72_ANEVI
Sequence: MNRLLVFLMLGAAFMLVVSANDAYGDEPAFKDLNQGDESLGKRKSCCPCWLRGNCFWGQNCYPEGCSGPKV
What is the function of this protein?
Voltage-gated sodium channel (Nav) inhibitor.  1 uM completely inhibits insect voltage-gated sodium channel inactivation (DmNav1 from D. melanogaster).
What are the official names of this protein?
Delta-actitoxin-Avd2b 2, Delta-AITX-Avd2b 2, Av7, Neurotoxin 7.
What is the protein family that this protein belongs to?
Belongs to the sea anemone short toxin (type III) family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: TAXB1_PONAB
Sequence: MTSFQEVPLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSPVEELLTMEDEGNSDMLVVTTKAGLLELKIEKTMKEKEELLKLIAVLEKETAQLREQVGRMERELNHEKERCDQLQAEQKGLTEVTQSLKMENEEFKKRFSDATSKAHQLEEDIVSVTHKAIEKETELDSLKDKLKKAQHEREQLECQLKTEKDEKELYKVHLKNTEIENTKLMSEVQTLKNLDGNKESVITHFKEEIGRLQLCLAEKENLQRTFLLTTSSKEDTFFLKEQLRKAEEQVQATRQEVVFLAKELSDAVNVRDRTMADLHTARLENEKVKKQLADAVAELKLNAMKKDQDKTDTLEHELRREVEDLKLRLQMAADHYKEKFKECQRLQKQINKLSDQSANNNNVFTKKMGNQQKVNDASVNTDPATSASTVDVKPSPSAAEADFDIVTKGQVCEMTKEIADKTEKYNKCKQLLQDEKAKCNKYADELAKMELKWKEQVKIAENVKLELAEVQDNYKLQLAEKDKEISGLTSHLENLSREKELKRSLENQAERKMEGQNSQSPQCLKTCSEQNGYVLTLSNAQPVLQYGNPYASQETRDGADGAFYPDEIQRPPVRVPSWGLEDNVVCSQPARNLSRPDGLEDSEDSKEDENAPTAPDPPSQHLRGHGTGFCFDSSFDVHKKCPLCELMFPPNYDQSKFEEHVESHWKVCPMCSEQFPPDYDQQVFERHVQTHFDQNVLNFD
What is the function of this protein?
Ubiquitin-binding adapter that participates in inflammatory, antiviral and innate immune processes as well as selective autophagy regulation.  Plays a key role in the negative regulation of NF-kappa-B and IRF3 signalings by acting as an adapter for the ubiquitin-editing enzyme A20/TNFAIP3 to bind and inactivate its substrates.  Disrupts the interactions between the E3 ubiquitin ligase TRAF3 and TBK1/IKBKE to attenuate 'Lys63'-linked polyubiquitination of TBK1 and thereby IFN-beta production.  Recruits also A20/TNFAIP3 to ubiquitinated signaling proteins TRAF6 and RIPK1, leading to their deubiquitination and disruption of IL-1 and TNF-induced NF-kappa-B signaling pathways.  Inhibits virus-induced apoptosis by inducing the 'Lys-48'-linked polyubiquitination and degradation of MAVS via recruitment of the E3 ligase ITCH, thereby attenuating MAVS-mediated apoptosis signaling.  As a macroautophagy/autophagy receptor, facilitates the xenophagic clearance of pathogenic bacteria such as Salmonella typhimurium and Mycobacterium tuberculosis.  Upon NBR1 recruitment to the SQSTM1-ubiquitin condensates, acts as the major recruiter of RB1CC1 to these ubiquitin condensates to promote their autophagic degradation.
What are the official names of this protein?
Tax1-binding protein 1 homolog.
Protein: RL32_ANAPZ
Sequence: MAVPKRKKSKSRRNMHRSHLGLVAPNVVIDPTTGEYKLSHHVCLGGYYNGKQVAKSKV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RF1_SYNFM
Sequence: MFDRLESVAQKFRKLEEDLSNPELLANQKEYQKIAREHAEIAPIVEAYGLYKGLHRQLLDNQQLLEQETDPEMRELFRQEIAELKRQIEDTENGLKLMLAPRDPNDDKNVILEIRAGTGGEEAALFVSDLFRMYTRYAELRRWKVEILDSHQTGIGGLKEVIAAVNGQGAYSRLKFERGVHRVQRVPVTESQGRIHTSAVTVAVLPEAEEVDVYIDPNDLRVDVFRSSGPGGQSVNTTDSAVRVTHIPSGLVVICQDEKSQHKNKAKALKVLRARLLDQMQSEQEARIARDRKSQVGTGDRSERIRTYNFPQNRVSDHRINLTLYKLDIILGGALDEIIDPLSTHFQAEALRREE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA76B_MOUSE
Sequence: MAASALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGAPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHSKHHHHHHHHHHRHSSGHHKVSSLSPEQEQGLWKQSHKSSAAIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSVLTSP
What are the official names of this protein?
Protein FAM76B.
What is the protein family that this protein belongs to?
Belongs to the FAM76 family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: YAE1_MAGO7
Sequence: MHMNPTPLPHSEDDGVMFASIGQTTLALTEPPSALHATDTLDDVFGSEDVQGSTSFTTEPSDMRRLQSEHTTAGYREGVTVAKAASVQAGFDEGFGLGATLGLSAGEIVGVLEGLAAAVPGDERLAALLGEARGDFSARSIFGATYWDPNGTWTYPVPGQDGGDVIFRDVVEAHPLIAKWRVVLNEQIQNWGVRCDFFAEDQVVDEEVVSQKKLGNPATALKAATSTAPATQSRMSDALQW
What is the function of this protein?
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery.  May be required for biogenesis of the large ribosomal subunit and initiation of translation.
What are the official names of this protein?
Protein YAE1.
What is the protein family that this protein belongs to?
Belongs to the YAE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y2940_SHELP
Sequence: MLDTKFHELLDFPAAFPFKVVGDARDTLADDVVAVVQRHVPGDYMPTSRASSKGSYHSITVKVTVHSKEQIELLYIELAAIEGVKRVL
What are the official names of this protein?
UPF0250 protein Shew_2940.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: RS12_NATPD
Sequence: MANGKYAARKLKQDRQKHRWSDSDYARRARGLGKKSDPLEGAPQGRGIVLEKVGIEAKQPNSAIRKCVRVQLIKNGKQVTAFCPGDGAISFIDEHDEVTIAGIGGAKGRAMGDLSGVNYKVEKVNGVSLIELVRGNAEKPVR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NEDD8_BOVIN
Sequence: MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGGLRQ
What is the function of this protein?
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53.  Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.  Attachment of NEDD8 to p53/TP53 inhibits p53/TP53 transcriptional activity.  Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M.
What are the official names of this protein?
NEDD8, Neddylin, Ubiquitin-like protein Nedd8.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Nucleus. Note=Mainly nuclear.
Protein: SYP_BACP2
Sequence: MRQSLTFIPTLREVPADAEAKSHQLLVRAGFIRQNTSGIYHYLPLAHKVIQHIQSIVRKEMEKAGAAELLMPVLQQAEMWQESGRWYTYGPELMRMKDRHGREFALGPTHEEVITSLVRSEVKSYKKLPLTLYQIQSKFRDEQRPRFGLLRGREFIMKDAYSFHSSPESLDDTYNKMFTAYSNVFSKVGLNFRPVIADSGAMGGKDTHEFMALSEVGEDTIAYSDTSSYAANIEMAEAVYQGEEANPADFKELEKVHTPQVKTIQDIAGFLDVDPSLCIKSVLFKADDAYVLILTRGDHEVNDVKVKNLVGAQLVELATREEVLEVIGTEPGFVGPVKLEAEVDIYADLTVKGMTNAVAGANEADYHYVNVNPARDVSVKEFTDLRFIQEGDVSPDGEGTIQFAKGIEVGQVFKLGTRYSESMDATYLDENGRAQPMIMGCYGIGISRTLSAIVEQHHDEKGIIWPEAVAPYDLHLLALNMKNDAQKELAETLYERLENEGFDVLFDDRQERAGVKFADSDLIGLPIRISCGKRSEEGIVEVKFRKSGESHEVSVDELISFIRQA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_PSEFS
Sequence: MSVESFTPTALQFTHGAAHKVKSLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVADDDTIVEREGVSLVVDPMSFQYLAGAEVDYQEGLEGSRFVIKNPNATTTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: VA5_VESMG
Sequence: MKISGFVYLILITTIINLSFSEANNYCKIKCRSGIHTLCKFGISTKPNCGKNVVKGSGLTKAEKLEILKQHNEFRQKVARGLETRGKPGPQPPAKSMNTLVWNDELAQIAQVWASQCKYGHDDCRNTAKHSVGQNIAQQSTTAASFGSVSNMVQMWADEVKNYQYGSTKNKLIEVGHYTQMVWAKTKEIGCGSIKYIENGWHRHYLVCNYGPAGNIGNEPIYEKK
What are the official names of this protein?
Venom allergen 5, Antigen 5, Ag5, Cysteine-rich venom protein, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family. Venom allergen 5-like subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SAT_SYNJA
Sequence: MTVSGDAIPPHGGTLVNRIASPEQAQELRSKAEHCPILHLDERAQSDLEMIAIGGFSPLTGFMGREDYQSVLETMHLANGLAWSLPVTLPVSAEIAADLKEGQTIALANAEGRLLGLLELTEKFTYDKTREAQQVYRTTDEQHPGVKVLYQQGSVYLAGPVTLLQRDPHPLFPAYQIDPAQSRQLFRERGWKTIVGFQTRNPIHRAHEYIQKCALEIVDGLFLHPLVGATKSDDIPAEVRMRCYEVLIEKYYPKERVILAINPAAMRYAGPREAIFHALVRKNYGCTHFIVGRDHAGVGNYYGPYDAQHIFDEFRPEELGIIPLKFEHAFYCTVTGTMATAKTSPSQPHQRIHLSGTKVREMLRRGEIPPPEFSRPEVAQLLAEAMRERGQPE
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: UVRB_LEPBP
Sequence: MANFKMVSPFKAAGDQVKAIENIAKSFGEGKNKITLVGVTGSGKTFTMAEVITRVKKPTLILSHNKTLAAQLFREFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDMSMNEEIDKLRLRATSSLLERDDVIIVSSVSCIYGLGSPEDYMNSVVMLQVGDKIDRDQIIRKFLHIQYARNDIDFSRGNFRVRGDTIEIMPSYQEEGIRIELFGDEIDGLSKIDPLTGKVKIKLDRVVVYPAKHFITSGPKIKDAMEKIKEEMAAQKEYFLKQGKHLEAERIESRTNYDMEMLLELGYCSGIENYSRHLTGRAEGERPACLLDYFPGKDFLLIIDESHVTLPQIGGMYAGDRSRKQTLVEFGFRLPSALDNRPLNFTEFEAMTPRTLYVSATPDQNELNKSEAVFEQIIRPTGLLDPVVEVRPTTNQIEDLLNEIRLRINQKERVLITTLTKKMSEDLTDYYKEVGLKIAYLHSEIDTIERTEIIRDLRKGVYDCIVGINLLREGLDIPEVSLVAILDADKEGFLRNYKSLVQTIGRAARNVNGKAILYADRMTDSIKKAMSETERRRLIQEAHNEKMGITPQTIQKEIHDILPREMAEEDSKEEALKDLEKEFTLKKYKTKDKLREALKREMLRYANDMDFEKAAMFRDKMLALGPDKIET
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBDP_ACET2
Sequence: MSIKKLILAASILTTLALTGCGGKGAVQPSGVSTGDVNAKIVFDNDKVNADNVDGLSVSEREVKITKPGMYTFSGTWNDGQILVDIGKEFEAVLVLDGVNITNTKSAPIYIKSAEKVKIELADGKDNVLTDAEFYEFEDPQDNKPNACIYSRDDITIKGNGNLTVNANFNNGIGTSNDLKITGGNITVKAFNNGLKGNDSVTISGGNIDITAEADGIKVENTEEPHKGYVNITGGTIKIRAKDDAIDSVRSVSINNADVKVSVGGKDVKCEGVLNIAEGCLGKLEE
What is the function of this protein?
Binds cellulosic and pectic substrates.  Displays no enzyme activity (in vitro).
What are the official names of this protein?
Carbohydrate-binding domain-containing protein Cthe_2159, Polysaccharide lyase-like protein Cthe_2159, PL-like protein Cthe_2159.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: KT395_PICKL
Sequence: GYQVDCVSYNYDNVNENLAQQFVDTQG
What are the official names of this protein?
Killer toxin KT395.
What are the subcellular locations of this protein?
Secreted.
Protein: YMU7_YEAST
Sequence: MACLHTYIYIYIYIYNRTTCTRPWHTPSKDRLFECILHFLSQLARIRAPANGCTFEDGPCLLGLPKSASPSSRRRVFIGDSAYCRDHPRRNGLIRTRKVKLISVGRRVSFFSRRRPFIGPETV
What are the official names of this protein?
Putative uncharacterized protein YMR057C.
Protein: CSRA_THESQ
Sequence: MLVLTRRVGEKIVIGEDIVITVLKIEGNSVKIGIEAPRHVKILREELYEELKSENIKASEVSKDDLKGVLKNDKGYKGPGTSS
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_PSEU2
Sequence: MAKEKFDRSLPHVNVGTIGHVDHGKTTLTAALTRVCSEVFGSAAVEFDKIDSAPEEKARGITINTAHVEYKSLIRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPYIVVFLNKADLVDDAELLELVEMEVRDLLSTYDFPGDDTPIIIGSARMALEGKDDNEMGTTAVRKLVETLDSYIPEPVRVTDKPFLMPIEDVFSISGRGTVVTGRIERGIVKVQDPLEIVGLRDTTVTTCTGVEMFRKLLDEGRAGENCGVLLRGTKRDDVERGQVLVKPGSVKPHTQFEAEIYVLSKEEGGRHTPFFKGYRPQFYFRTTDVTGSCELPEGVEMVMPGDNVKVSVTLIKPIAMEDGLRFAIREGGRTVGAGVVAKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A33_PLEWA
Sequence: MANSTVAEPEKMEQSGTCEEDEEEENMEGDEDECDDDEEENMEPAETVTIGSTYKCRRSDNTLHAAEIIKTRKTKENAEEFYVHYVGLNRRQNEWVDKSRVLQAKQIKTEELNNTEDETNGVSDQSEGKAARSNKRKIEDGDGDQKKRKVDDEEDDFTEDLTCPLCRSLFKEPVILECGHNFCKHCIDKSWESASAFSCPECKEVLTERKYTTNRVLANLVKKAAVGVKDKDVKPKEKCDEHDERLKLFCKDDGTLACVICRDSLKHSNHNFLPIQDAVGVYRDQLIALVSPLETTMKENQKLKCDQSQKISLHRENIVDCKKHIECEFEKLHQFLREKEAKMVEDLNAEREGLLKDMEANLVKMTDNCEFIEEAISTTQSRLNESDPIAFLTDIKSFIEKCCEEHRKGVPAESVLVNKELSQGRFKGPLQYIIWKELKSVVQPGLAPLTLDPNTAHPNLVLSEGLTSVKYTDTKQQLPDNPKRFSQCILVLGAEGFDSGKHYWEVEVGNKTAWDVGMASESSNRKGKIKLNPKNGYWAIWLRNGNAFKALESPSKTLNLTSKPSKIGVYLDYEGGQVSFYNADDMSPIYTFNGSFTEKLYPYLSPFLQDSGKNAEPLKLVHTKL
What is the function of this protein?
May be a nuclear regulatory protein that is stored in the germinal vesicle for use during early embryogenesis and may play a role in the synthesis or processing of pre-mRNA during oogenesis.  Binds 3 Zn(2+) ions.
What are the official names of this protein?
Zinc-binding protein A33.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Lampbrush chromosome loops and in some nucleoplasmic particles of the germinal vesicle.
Protein: TBP_ASFP4
Sequence: MEDETELCFRSNKVTRLEMFVCTYGGKISSLACSHMELIKILQIAEPVKALNCNFGHQCLPGYESLIKTPKKTKNMLRRPRKTEGDGTCFNSAIEASILFKDKMYKLKCFPSTGEIQVPGVIFPDFEDGKNIIQQWVDFLQHQPIEKKIQIIEFKTIMINFKFQINPVSPRVIIHLKKFAALLEHIPTPYPIREIKPPLEDSKVSAKFMVSPGKKVRINVFLKGKINILGCNTKESAETIYTFLKDLISVHWQEILCVLPMPD
What is the function of this protein?
Putative TATA-binding protein.
What are the official names of this protein?
Putative TATA-binding protein pB263R, TBP.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B263R family.
Protein: RL30_BACC1
Sequence: MAKKLEITLTRSVIGRPQDQRATVEALGLKKLNSTVVKEETPAILGMINKVSHLVTVKEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: DEF4_MACMU
Sequence: MRTIAILAAILLFALLAQAKSLQETADDAATQEQPGEDDQDLAVSFEENGLSTLRASGSQARRTCRCRFGRCFRRESYSGSCNINGRIFSLCCR
What is the function of this protein?
Exhibits bacteriostatic activity against Gram-positive bacteria S. aureus and L. monocytogenes and Gram-negative bacterium E. coli, antifungal activity against C. neoformans and microbicidial activity against Gram-positive bacteria S. aureus and L. monocytogenes.
What are the official names of this protein?
Defensin alpha 4, Neutrophil defensin 4, RMAD-4.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPEE_YERPS
Sequence: MSQKELWYETLHANFGQYFSVENVLYREKTEHQDLVIFENPELGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGQAKKVLIIGGGDGAMLREVSRHKNIEQITMVEIDAGVVEFCRQYLPNHSAGAYDDPRFKLVIDDGVNFVNQTTEKFDVIISDCTDPIGPGESLFTSVFYEGCARSLNEGGIFVAQNGVCFLQQDEAVNSHNKLSHYFSDVSFYQAAIPTYYGGIMTFAWATQNPALRQLDLATLQNRFAQAGLACRYYNPAIHVGSFALPQYLLDALTTIPKVIGVDSSE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_VIBCM
Sequence: MPRRRVIGQRKILPDPKFKSELLAKFVNILMVDGKKSTAEKIVYTALDTMAEKSGKDHLAVFEEALENVRPAVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWLVEAARKRGEKSMAARLAAEMLDAAENKGSAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: NUON_ECOBW
Sequence: MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIPB_XENLA
Sequence: MEAERRHRALYKGTTPPWKETYRKRCVERLKSNRSKLLDKFRQVGERIHGGVGGSFLVQEVMEEEWKVMQFENGGFPSMWKKDAFSQDPDELATLEEIKQELLLEEKAMVEEFENILQFEEQCFDSVVELSTGDQIVCPVCNRNYLTVTSCFIVCQCGVYINTQSQGMSIEKLHSLLESNLTAHAYHCNKLPVFSVATELGGAASLFMSCQECDAMVVIL
What is the function of this protein?
Mediates the import of RPA complex into the nucleus, via its interaction with importin beta.
What are the official names of this protein?
RPA-interacting protein B.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFG_STRPM
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAVAETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIAYLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIAGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AG1_XENTR
Sequence: MQTGLSLVCLVLLCSALGEAALRKTKKQAVVTDTGNSAKSDPEPVPIKTKGLKTLDRGWGEEIEWVQTYEEGLAKARENNKPLMVIHHLEDCPYSIALKKAFVADRLAQKLAREDFIMLNLVHPVADENQAPDGHYVPRVIFVDPSLTVRSDLKGRYGNKMYAYDADDIPELVTNMKKAKSYLKTEL
What is the function of this protein?
Probably involved in cement gland formation.
What are the official names of this protein?
Anterior gradient protein 1.
What is the protein family that this protein belongs to?
Belongs to the AGR family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPG_LIMRD
Sequence: MPASLAAVKHKIDSTKSTRQITSAMQMVSTAKLNQIQHHTQTYEVYAEKVKQMLSDLVKSHSATSAASQDDVYAALFKKRAVKKTGVLVITSDRGLVGSYNSNIIKQTLDMMAKHNLDKDNTVFLTVGKTGTEFFKKRGMNVVYEYSGVSDVPTYREVHSIVKTAVQMYSDQVFDEMYMVYSHYVNRITSNVIVHDVLPITEKSLLDDENEAQENTELNNSDVSTAHVSAEYEFEPSDTEIISALVAQYAESLIYGAILDAKTSEHSSSANAMRSATDNADDIISTLELQYNRARQAAITTEITEITGGMTAQE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HBA_TAPTE
Sequence: VLSPTDKTNVKAAWSKVGSHAGEYGAEALERMFLGFPTTKTYFPHFDLSHGSAQVQAHGKKVGDALTQAVGHLDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLALHHPDDFTPAIHASLDKFLSNVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1/2, Alpha-1/2-globin, Hemoglobin alpha-1/2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.