PharMolix/UniProtQA huggingface dataset:
Protein: HPPA_BRUME
Sequence: MQMGMAVLVLVIACGVLSVLFAIWAIRSVLAADQGTQRMQEIAEAIREGASAYLTRQYSTIAIVGIVVFLLAWYLLSLNAAMGFLIGAVLSGVTGFIGMHVSVRANVRTAQAASLSLAGGLELAFKSGAITGLLVAGLALLGVSVYYFVLTVWLGYAPADRTVIDSLVSLGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVVATMVLGAIFFHGSDALTNVMLYPLMICGACVITSIAGTFFVKLGVNGSIMGALYKGLIATGLLSIVGLGVANTLTVGWGEIGTVAGKSITGTNLFVCGLIGLIVTGLIVVITEYYTGTNKRPVNSIAQASVTGHGTNVIQGLAVSLESTALPAIVIVGGIISTYQLAGLFGTAIAVTAMLGIAGMIVALDAFGPVTDNAGGIAEMAGLDPEVRKATDALDAVGNTTKAVTKGYAIGSAGLGALVLFAAYSNDLAYFAANGQIYPYFADMGPVSFDLSNPYVVAGLIFGGLIPYLFGGMAMTAVGRAGGAVVQEVRRQFREKPGIMTGKERPDYARAVDLLTKAAIREMIIPSLLPVLAPIVVYFGVLLISGSKAAAFAALGASLLGVIINGLFVAISMTSGGGAWDNAKKSFEDGFTDADGVKHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIVALLLLAVLAHMA
What is the function of this protein?
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane.  Generates a proton motive force.
What are the official names of this protein?
K(+)-insensitive pyrophosphate-energized proton pump, Membrane-bound proton-translocating pyrophosphatase, Pyrophosphate-energized inorganic pyrophosphatase, H(+)-PPase.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1214_PSEPK
Sequence: MAGHSKWANIKHRKERQDAKRGKVFTKWIRELTVAAKQGGPDPASNPRLRLALDKALGANMSRDIIDRAVARGAGTNESDNVEELSYEGYGPGGVAIMVEAMTDNRNRTAAAVRHAFTKCGGNLGTDGSVAYLFERKGQISFAPGVEEDALMEAAMEADADDVVANDDGSFDVFTSFNSFYAVRNALEEAGFKAADAEIVMQPTTSAELDQDGAEKVLKLIDMLEDLDDVQNVYSNAQISDEIMENLG
What are the official names of this protein?
Probable transcriptional regulatory protein PP_1214.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGL13_ORYSJ
Sequence: MAAAGEVVMLGGILLPLLLVVAVSGEPPPISRRSFPEGFIFGTASSSYQYEGGAREGGRGPSIWDTFTHQHPDKIADKSNGDVAADSYHLYKEDVRIMKDMGVDAYRFSISWTRILPNGSLSGGINREGISYYNNLINELLLKGVQPFVTLFHWDSPQALEDKYNGFLSPNIINDYKEYAETCFKEFGDRVKHWITFNEPLSFCVAGYASGGMFAPGRCSPWEGNCSAGDSGREPYTACHHQLLAHAETVRLYKEKYQVLQKGKIGITLVSNWFVPFSRSKSNIDAARRALDFMLGWFMDPLIRGEYPLSMRELVRNRLPQFTKEQSELIKGSFDFIGLNYYTSNYAGSLPPSNGLNNSYSTDARANLTAVRNGIPIGPQAASPWLYIYPQGFRELVLYVKENYGNPTIYITENGVDEFNNKTLPLQEALKDDTRIDYYHKHLLSLLSAIRDGANVKGYFAWSLLDNFEWSNGYTVRFGINFVDYNDGAKRYPKMSAHWFKEFLQK
What are the official names of this protein?
Beta-glucosidase 13, Os4bglu13.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: MUTS_PSEAE
Sequence: MTDLSQHTPMMQQYFKLKHQHPDQLMFYRMGDFYELFYEDAKKAAKLLDITLTARGQSGGKAIPMAGIPFHSAEGYLAKLVKLGESVAICEQIGDPATSKGPVERQVVRIITPGTVSDEALLDERRDNLLAAILGDERLFGLAVLDITSGRFSVQEIKGWETLLAELERLNPAELLIPDDWPQGLPAEKRRGVRRRAPWDFDRDSAHKSLCQQFGTQDLKGFGCQNLTLAIGAAGCLLAYAKETQRTALPHLRSLRHDRLDDTVILDGASRRNLELDINLSGGRENTLQSVVDRCQTAMASRLMSRWLNRPLRDRAVLEARQESIACLLERYRFENLQPQLKEIGDLERILARIGLRNARPRDLARLRDALAALPDLQNAMTELEAPHLQALATTIGTYPELAELLAKAIIDNPPAVIRDGGVIKTGYDAELDELQALSENAGQFLMDLEAREKARTGLPNLKVGYNRIHGYFIELPRVQAEQAPADYIRRQTLKGAERFITPELKAFEDKALSAQSRALAREKALYEELLERLIGHLAPLQDSASALAELDVLANLAERALNLDLNRPRFVEHTCLHIEQGRHPVVEQVLETPFVANDLALDADTRMLVITGPNMGGKSTYMRQTALIVLLAHIGSFVPAARCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNATDKSLVLMDEVGRGTSTFDGLSLAWAAAEDLARTRAFTLFATHYFELTVLPESQPAVANVHLNATEHNERIVFLHHVLPGPASQSYGLAVAQLAGVPAPVIQRAREHLKRLETTSLPHEMPSQQSGKPASPMQSDLFASLPHPVIDELSRINPDDISPRQALDLLYAWKMRV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL16_LEGPL
Sequence: MLQPKRTKYRKQMKGRNRGLALRGSKISFGEFGLKAVERGRLTARQIEAARRAMTRHIKRGGKIWIRVFPDKPITQKPLEVRQGKGKGSVEYWVAQIQPGKVLFEMEGVSKELAMEAFDLAKAKLPFKVMFEERTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PUR5_ANADE
Sequence: MSLTYRDAGVDIDEGDRLVDLIKPHARPTLRPEVLGGIGGFGGLFALDVKKYREPVLVSGTDGVGTKLKVAFAADRHDTVGIDLVAMCVNDIAVVGAEPLFFLDYYATGKLSAEQGAEVVKGIAEGCRQAGCALIGGETAELPGFYARGEYDLAGFAVGCVDRPRIVDGTRVARGDVVIGIASSGLHSNGFSLARKALLDRYPLDHRFEGLGGRTLADALLEPTRIYAKDVLALLDQVPVRAFAHITGGGLPGNVPRTLPDGTRAVLEEKRWPRPAIFDVVEREGQVPRDEMYRTFNMGLGLVAVVAPGDEAAAHAALRARGLEAWTVGAIEAGGPGEATCEVVR
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA_I47A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGRSIIVELGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKEDRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEEKFEITGTMRNVADQSLPPNFSCLENFRAYVDGFKPNGYIEGKLSQMSKEVNARIEPFFKTTPRPIRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYVVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFDDCKDVSDLKQYYSDEPELRSISSWIQNEFNKACELTDSVWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIAPVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAVEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: RL17_MARN8
Sequence: MRHRKSGRKFNRTSAHRKAMFRNMTASLVEHELIKTTLPKAKELRRVAEPLITLAKNDSVANRRLAFSRLRSDAAVAKLFDELGPRYSERPGGYLRILKCGFRAGDNAPMAFVELVGRPLDIEAEEMDDDEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SOCS3_HUMAN
Sequence: MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPSAQPLPGSPPRRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
What is the function of this protein?
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction.  SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway.  Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including IL6ST/gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors.  Binding to JAK2 inhibits its kinase activity and regulates IL6 signaling.  Suppresses fetal liver erythropoiesis.  Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells (By similarity).  Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:15601820).
What are the official names of this protein?
Suppressor of cytokine signaling 3, SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SSI-3.
Protein: DUT_CHLFF
Sequence: MTIFCELESGVDLPEYATEGASGADLRANIEEPIAVLPGQRVLVPTGIKMQIPQGYEVQVRPRSGLALKHGIMVVNSPGTIDADYRGEVCIILANFGESTFIIEPKMRVAQAVVAPVVQAKFIVVDQEEGLTTTSRGSRGFGHTGEK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: YIDC_AERS4
Sequence: MESQRNLILIGLLFVSFLLWQQWESDKAPKPAPTTVAQTEHFVPEAGQTGDIPQVSEQANANAARKLITVSSDVLKLTLDTQGGDIVSAELLAHKLEEGKDQSFVLLTSQPDRLYVAQSGLVGRDGPDSQAQGRPTYEAAQTSYQLADGQDQVVVPMTWTDSKGVVFTKEFVLKRGDYAIGVDYKIDNKSAEPVQVQFYGQLKQTVTTPKDQEGHAMVASAYRGGAFSSEESRYKKYTFDEMKDADLNKTTKGGWVAMLQHYFVSAWAPNADDTNSFYSRVIPGKDQAIIGYKAPLVDVAAGQQAEVTSKLWVGPKLQDQMAKVANHLDLTVDYGWLWFIAQPLHWLLTVFQGFVHNWGVAIIMLTLLVRGIMFPLTKAQYTSMAKMRMLQPKLAALKERFSDDRQKMSQGMMELYKKEKVNPLGGCLPILVQMPIFIALYWALMESVELRHAPFALWITDLSVKDPFFVLPILMGASMWYLQKMSPTTITDPMQQKVMQFMPIIFTFMFLWFPAGLTLYWLVSNVISITQQTIIYRQLEKKGLHTRT
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACRG_ASPA1
Sequence: MSPAKVSANDVPMHGNGFYSSNSALQHSAMLNALPLLAAAAAASKAKQQEEQENSRPFAILEFGSAHGNNSHTPITTVLKSRAPAPSREIHLQFNDRPTNDFSTLATNLTTMTWPVSNAIFTSLLPASFYSRVSPKGSVDVAFSLAALHHLDRVTPVPPEGPIPTHEVRQAEFRAQAHADLLSFLSHRAEEIVPGGGLVLSFVGQELGPNGEEITNYAGPVDACRSAMIDMLQAGVLSPAVANVFEVPAYNRTIADVRRTLAEGEVVAAWEVEEVFERKVVHPALQELEARREAAPGKEEEHAEWYARTVVDWLMAVVAGYFVKAVREGMGVTDQTVLDGLLAEWVERTRGRFLEGHRNEPVECWFVYVRLGRK
What is the function of this protein?
O-methyltransferase; part of the cluster that mediates the biosynthesis of acurin A, a highly reduced polyketide coupled to a serine via a peptide bond (PubMed:32234543).  The activities of the highly reducing polyketide synthase acrA and the nonribosomal peptide synthetase acrB are collectively responsible for the synthesis of the acurin A core structure with a heptaketide backbone produced by acrA covalently fused to a L-serine by acrB (PubMed:32234543).  After the formation of the PK-NRP hybrid product, it is detached from acrB by reductive release to set up the formation of the lactam ring by aldol condensation (Probable).  The hydrolyase acrC then catalyzes water loss to generate a double bond in the ring (Probable).  This double bond is probably reduced, which is followed by three oxidations at C-22 to generate the carboxylic acid moiety, involving probably the FAD-binding monooxygenase acrE and the cytochrome P450 monooxygenases acrD and acrF (Probable).  Finally, a last methylation step performed by the O-methyltransferase acrG leads to the production of acurin A (Probable).
What are the official names of this protein?
O-methyltransferase acrG, Acurin A biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: CHIA1_ASPFM
Sequence: MVSSKLSFVATAVAALAPLASAFDASSRSNLAIYWGQGPNQLRLSHFCQETSLDIINIGFINYFPDMSPGHWPGSNFGNQCDGSVYVTNDGVVTKLLSGCHQIMEDIPICQAAGKKVLLSIGGAYPPDQSILSEDSAVAFATFLWGAFGPVAEGWEGPRPFGDVVVDGFDFDIEHNGGFGYATMVNTFRQYFNQVPERKFYLSAAPQCIIPDAQLSDAIFNAAFDFIWIQYYNTAACSAKSFIDTSLGTFNFDAWVTVLKASASKDAKLYVGLPASETAANQGYYLTPDEVESLVSTYMDRYPDTFGGIMLWEATASENNQIDGAPYADHMKDILLHCDPSPPVTSSSAVPSSTPVTTPSPSSSAVPSSTPAVSETPSPSSSAVPSSTPVASSTPVVPGTSASSSPVSSSSAIAPSTPVVPGTSTPSSTPVASSTPVVPGTSASSSPVSSSSAVASSTPVVPGTSVPSSTPAIPGGSSSSSEAVASSTPLVTLTLTVSPTPAPSSSESSSTDLSSSTQTDVGTAPSQPAGPSTTATATTSSSSSSTDESSTTVGSGNGNGSGSTTTTAATDSITAAPTATSSATATGATSEPVTITTIIVTSYIDICPTGFTTVTTTYTTTYCPGTNTATATATVTNPPSGPGGAGSQTTAPTVPEGWTTTVTVCTQCAAKPTTVTLTLPVTETGSTSTDAVPAPPAATGEGSNPTQPSGASPTGGNGSFSEEPVPPPAVTQVSTSTEIVTLVRPTSSRPLILGTGTVHPSSTLAVKPSAKPSGQNSGSSSHVPIPPSYTQEAVSPLSTGAASRVTGLGHGLVLTVLTLSAFFVL
What is the function of this protein?
GPI-anchored chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods).  Required to reshape the cell wall at the sites where cell wall remodeling and/or cell wall maturation actively take place such as sites of conidia formation.
What are the official names of this protein?
Endochitinase A1, Chitinase A1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted, cell wall.
Protein: ATPA_BRUC2
Sequence: MDIRAAEISAILKEQIKNFGKEAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIRGMALNLESDNVGVVIFGADRDIKEGDVVKRTGAIVDVPVGPELLGRVVDALGNPIDGKGPIKAKERRRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPVGRGQRELVIGDRQTGKTAIILDTFLNQKPIHDNGPDKDKLYCVYVAVGQKRSTVAQFVKVLEERGALEYSIVVAATASDPAPMQYLAPFAGCAMGEYFRDNGQHALIGYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDENGAGSLTALPVIETQGNDVSAFIPTNVISITDGQIFLETNLFYQGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKGELAQYREMAAFAQFGSDLDAATQRLLNRGARLTELLKQPQFSPLKTEEQVAVIYAGVNGYLDKLAVNQVGKFEEGLLASLRTEHKDVLEGIRNEKALTDDLKAKLKAAIDAFAKSFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YKZM_BACSU
Sequence: MSKDKQQKKAVHTKSREALFDTADLIKHAKELFGVKPDILQGALFGVDQPRMTKSEANQLIQTFLTKEVMSS
What are the official names of this protein?
Uncharacterized protein YkzM.
Protein: CTBP_ARATH
Sequence: MSKIRSSATMPHRDQPSPASPHVVTLNCIEDCALEQDSLAGVAGVEYVPLSRIADGKIESATAVLLHSLAYLPRAAQRRLRPHQLILCLGSADRAVDSTLAADLGLRLVHVDTSRAEEIADTVMALILGLLRRTHLLSRHALSASGWLGSLQPLCRGMRRCRGMVLGIVGRSVSARYLASRSLAFKMSVLYFDVPEGDEERIRPSRFPRAARRMDTLNDLLAASDVISLHCALTNDTVQILNAECLQHIKPGAFLVNTGSCQLLDDCAVKQLLIDGTIAGCALDGAEGPQWMEAWVKEMPNVLILPRSADYSEEVWMEIREKAISILHSFFLDGVIPSNTVSDEEVEESEASEEEEQSPSKHEKLAIVESTSRQQGESTLTSTEIVRREASELKESLSPGQQHVSQNTAVKPEGRRSRSGKKAKKRHSQQKYMQKTDGSSGLNEESTSRRDDIAMSDTEEVLSSSSRCASPEDSRSRKTPLEVMQESSPNQLVMSSKKFIGKSSELLKDGYVVALYAKDLSGLHVSRQRTKNGGWFLDTLSNVSKRDPAAQFIIAYRNKDTVGLRSFAAGGKLLQINRRMEFVFASHSFDVWESWSLEGSLDECRLVNCRNSSAVLDVRVEILAMVGDDGITRWID
What is the function of this protein?
Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity).  Required for cortical microtubules (MTs) arrangement that confers cell shape.  Regulates the width of leaves by controlling the polar elongation of leaf cells.  Involved in the regulation of trichome branching.  Seems to not be able to regulate gene transcription.  Regulates epidermal cell divisions and elongation in a non-cell-autonomous manner (regulated by subepidermal cells), but regulates epidermal cell polarity, shape, trichome branching and elongation in a cell-autonomous manner.  Negatively regulates growth in the petiole elongation.  Prevents lipid peroxidation as a result of abiotic stress response.  Is involved in the SUB-dependent signaling mechanism and may act in a membrane trafficking event around the trans-Golgi network.
What are the official names of this protein?
C-terminal binding protein AN, CtBP, Protein ANGUSTIFOLIA, Protein DETORQUEO.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. Plant AN subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network. Note=Was thought initially to be located in nucleus (PubMed:11889033 and PubMed:11889034) but the large dot-like structures are now believed to represent non-physiological aggregates (PubMed:11889033, PubMed:11889034). In root cells, cytoplasmic polarized localization near cell edges, at the vicinity of SOKs proteins (PubMed:32004461). Associates with membranes in puncta in embryos (PubMed:32004461).
Protein: HNT1_SCHPO
Sequence: MSCIFCKIVKGDIPCVKLAETALSLAFLDIAPTSKGHALVIPKEHAAKMHELSDESCADILPLVKKVTKAIGPENYNVLQNNGRIAHQFVDHVHFHIIPKPNEEYGLGVGWPSYPISPEEIKALGEEISSKIK
What is the function of this protein?
Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2.
What are the official names of this protein?
Adenosine 5'-monophosphoramidase hnt1, Histidine triad nucleotide-binding protein HNT1, HINT, Hit family protein 1.
What is the protein family that this protein belongs to?
Belongs to the HINT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOC_THEM4
Sequence: MMGSTFKRKISKVTVKVASPEVIRSWSSGEVKKPETINYRTFKPEKDGLFCEKIFGPTKDYECACGKYKGKKYEGTVCERCGVRVESKEARRKRMGHIDLFAPVVHVWYLKSSPSILSSLLGIQAKELENVIYYGGKRIIEKILIVTNPKDTDFIKGSLLYQTEYEIYNQKLDFEVMPGVIIKSPVAPVISSISGEVKIRHEKTHTDREITWVDVRKISRAEHRVYNGMVLNVKNGDYVNQGDEIVSEMQIDPIYAPFDGTVEIDEISNTITIKPLTTSKDMPVTFSLPYGVKPVVPNNSKVKKGDQLTNGTVLPAVIASVSGNISFGKELNVRPLEDGKYEVLTSGSVYVENVVEEKHYPLFEGAFVYVKDGDEISEGQTIADRFLFEDEYLTLDEYKIFEQHYPAMFTAESEVENDRPIVVITEIDDEVSVETGLKIGDIITDHQYSAYRTLYNDKIEADSGASAIKKLLQKLDLEKLKAEIESELKKVSKSSGRAKKLLRRLKIVKDLLKSETKPEWMILEAIPVVPPDIRPMIQVEGGRFATTDLNDLYRRVINRNNRLKKLYEMNSPEIIIKNEKRMLQEAVDSLIYNGRMGKAVTDRNGRALKSLTDLLKGKKGRFRRNLLGKRVDYSGRAVIVVGPHLKIHECGLPKKMAMELFKPFVLAELLNKDDETSKTARKMKKAIIEKEMPQAYEVLEEIIKGHPVLLNRAPTLHRMSLQAFEPKLIEGNAIQLHPLVCPPFNADFDGDQMAVHVPLSAAAQAEAKFLMLSRYNIISPAHGKPISMPGKDIVAGVYYLTMVGKDYDKVQKENIKWKFSSIDEAELAYEFGHIRLHDPILVKVDDRVIKTTYGRLVFANIVPREFRDYNKTYGKGAIKDLVYKTFKKYGVDRTADLLDDIKDLGFHYATISGLTVSITDFYISPERRRIIDEAKKKISEVEELFALGFLSDEERYRETIKIWADATEKVQDATFEYIGKDPFNPVYIMVDSGARGNKDQLKQLAGMRGLMADPSGRTIEIPIISNFREGLSVLEFFISTHGARKGSADTALRTSSAGYLTRRLVDVAQSVVITTTDCGTENGVRATVLKSSDGLTVEKLEDFLFGRVLAKDVYDPKTNSVLVNPENGKEYTRDTMIDDDDAKFLGNYSVRIPVSRELEINLTNPELPENYCELITDFIYDGVHYDEGTEVNWDIIRKAKNSGLEKLTVKEYPIVGKVSVETVVSQKDIKQLVVDEELIMPTTAKILEGHNVESVQVRPEIIVRSVLTCEAEHGVCSKCYGMDLSNHKIIGVGEAVGVVAAQSIGEPGTQLTMRTFHTGGIATTADITQGLPRAEELFEARKKLKEPEGIFSRVKGYVKDIVEDETGKKKVYIEDEAGDIHEYDIPTKVKVSVNKGQKILPGQSLSTGAIRPRKILETLDVDTTALYLLKEIKKVYVEQGVDIHDKHFEIIIKQMLDKVEVIDPGDTDYLPGDLLRLQMVKRINKQILEENVHVETNRKRVIGKILHQHLIAEDENGEIVEIAPEGVEVTEEILEKAIKSGIKEIIVKNGDGEIVTYQILPKEPIKYRRRLLRITKASLERVGWLSAASFQQTPQVLTEAAIEGSVDHLLGLKENVIVGQLIPAGTGLDMFANIQIEETPRLAQKEKMA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ENGB_LEUMM
Sequence: MDVHNVEMVMSAVSASQYPTDGKPEIALVGRSNVGKSSLTNTLIQRKNFARTSSQPGKTQTLNFYDVEDKLYFVDVPGYGYAKVSKAQREAFGVMIEEYITSRKQLRGVISLVDARHEPSEDDISMYEWLHYYNIPILVVATKSDKISRGKFNKAESVIKKALGFDNEDSDFQFFSSETKYGKDEVWHWIEQHI
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PP4C1_CAEBR
Sequence: MALAVADTQNETFARSESPTSGPSDQLSTHDLDRHIEKLMRCELIAEQDVKTLCAKAREILAEEGNVQVIDSPVTICGDIHGQFYDLMELFRVGGPVPNTNYLFLGDFVDRGFYSVETFLLLLALKARYPDRMMLIRGNHESRQITQVYGFYDECMRKYGNASVWKHCTEVFDYLALAAVIDGKVFCVHGGLSPSISTMDQIRVIDRKQEVPHDGPMCDLLWSDPEEGNVGWGLSPRGAGYLFGADASKTFCEANSVDLICRAHQLVMEGYKWHFNEKVLTVWSAPNYCYRCGNVAAILELDENLNREFTIFEAAPQENRGAPAKKPHADYFL
What is the function of this protein?
Protein phosphatase which plays an essential role in meiosis and in early embryonic mitosis.  During spermatocyte meiosis and the first embryonic mitosis, regulates centrosome maturation, and thus spindle formation, by recruiting some of the components of the pericentriolar material (PCM).  During oocyte meiosis I, regulates meiotic chromosome dynamics including synapsis-independent chromosome pairing, restriction of synapsis to homologous chromosomes, programmed DNA double-strand break initiation and crossover formation resulting in chiasma formation.  During oocyte meiosis II and probably together with regulatory subunit ppfr-1, may regulate microtubule severing by dephosphorylating and activating mei-1, a component of the katanin microtubule severing complex.
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 catalytic subunit 1, PP4C-1.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes at centrosomes from prophase to telophase but not during interphase. Also localizes to the cytoplasm throughout the cell cycle.
Protein: TATB_YERPS
Sequence: MFDIGFSELLLVLVIGLVVLGPERLPVAVRTVSGWIRTLRSLAATVQNELAQELKLQELQDSLKKVEQAGLQNLTPELKASMDELKEAAEALKRSYHVDAGSEAPHTIHNPLVTEPEAIHDGVTPAEPATQVSALAQAPNILEAGTASVADSVVEAAPVTTVKSVVQGEVLVKSTPVQEVGLADVMDKPVTKQQIDTIDSHGTDLSSAGPSRIHQPGGDQ
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PYRI_CLOBH
Sequence: MLTINSIKNGIVIDHIQAGHGIKIFKYLGLEEADYRVALIMNAESSKLGKKDIIKIENIMEIDYKVLGFIDPTITIDVIENETIKEKIKLELPKTIENVIKCKNPRCITSIENYIPNEFYLVDEENGEYRCKYCDEIYSGGDINKL
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.