PharMolix/UniProtQA huggingface dataset:
Protein: ETHA_MYCBO
Sequence: MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKPILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGPIIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRWKNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERFTATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSEFVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRFAKRPAPVGV
What is the function of this protein?
Is responsible for the activation of several thiocarbamide-containing pro-drugs, such as ethionamide (ETH), isoxyl (ISO) and thiacetazone (TAC), into reactive species.
What are the official names of this protein?
FAD-containing monooxygenase EthA, Baeyer-Villiger monooxygenase, BVMO, Prodrug activator EtaA.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
What are the subcellular locations of this protein?
Cell membrane. Note=Is most likely membrane-associated.
Protein: NADA_ECOHS
Sequence: MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAKALEQEGSNHEVHVEERLRERALVPLNRMLDFAATLRG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKIB1_MOUSE
Sequence: MGNTTTKFRKALINGDENLACQIYENNPQLKESLDPNISYGEPYQHNTPLHYAARHGMNRILGTFLFGRDGNPNKRNVHNETSMHLLCMGPQIMISEGTLHPRLARPVEDDFRRADCLQMILQWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENRDTPCDCAEKQQHKDLALSLESQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQMPTPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCWEAFLNLKIQEGEAHNIFCPAYECFQLVPVDVIESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTAGCERAVRLTKQGSNPSGSDTLSFPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTVEAEKKHKRFQELDRFMHYYTRYKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDTTFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYLRTPRHKIIRAACLVQQKRQEFLASVARGVAPADSPDAPRRSFAGGTWDWEYLGFASPEYRRRHRQQRRRGDVHSLLSNPTDLDEPSESTFDLPEGSSGRRPGASVVSSASMSVLHSSSLRDYSPASRSANQDSLQALSSLDEDDPNILLAIQLSLQESGLDMDEETRDFLSNETSLGAIGSSLPSRLDSVPRSTESPRAALSSSELLELGDSLMRLGADSDPFSTDTLSSRPLSETRSDFCPSSSDLDSAGQDPSANDNLLGNIMAWFHDMNPQSIALIPPAATTEISAEPQLPCIRDGSEGVRDMELVPPEDSVSKDTGVHEGERAQMEENPLEENILAREELSQAGDSSNEAVGRGDRPDAASQTPQTSSDWLEQVHSV
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
What are the official names of this protein?
Ankyrin repeat and IBR domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RBR family.
Protein: 14332_ECHGR
Sequence: MAAITSWITDSGCKDHASLVSIAKLAEQAERYEDMAVAMKTIAEMGNELNNEERNLLSVAYKNVVGARRSSWRIMSSIAKKQAGTPLADQTDIYLKKVEEELTKICNDVLALLSKNLITEKIGAEAKIFYYKMMGDYYRYLAEVQEGEQNDKSTEAAEEAYQKATSLAEAELSVTHPIRLGLALNFSVFYYEIKNMPEKACSLAKAAFDAAITEVDSIKDETYKDSTLIMQLLRDNLTLWSSECETDS
What are the official names of this protein?
14-3-3 protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: DISA_MYCTO
Sequence: MHAVTRPTLREAVARLAPGTGLRDGLERILRGRTGALIVLGHDENVEAICDGGFSLDVRYAATRLRELCKMDGAVVLSTDGSRIVRANVQLVPDPSIPTDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVRGERHVLTDSATILSRANQAIATLERYKTRLDEVSRQLSRAEIEDFVTLRDVMTVVQRLELVRRIGLVIDYDVVELGTDGRQLRLQLDELLGGNDTARELIVRDYHANPEPPSTGQINATLDELDALSDGDLLDFTALAKVFGYPTTTEAQDSTLSPRGYRAMAGIPRLQFAHADLLVRAFGTLQGLLAASAGDLQSVDGIGAMWARHVREGLSQLAESTISDQ
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic-di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: RBFA_BURP0
Sequence: MSKKRSSPNRNVQIADQIQRDLSELIMREVKDPRIGIVTIQSVELTPDYAHAKVYFTALTGTPADTQEALNHAAGHLHNLLFKRLHIHTVPTLHFHYDQTIEKAVAMSRLIDEANATRAKDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_STACT
Sequence: MSNKAWGGRFQSEPEAWVDAFNASINFDHLLIDEDIQGSIAHATMLAQQGILTEDESNTIIKGLQEIQQDYHDGKIEFTEALEDIHLNIEHELIERIGAVGGKLHTGRSRNDQVATDLHLYTKKAVKEIIHLIHTLQETIVKLADDHVDTIMPGYTHLQRAQPISFAHHVMTYFWMLERDKNRFEDALKRIDINPLGAAALSGTTHPIDRAKTQELLDFAALYENSLDAVSDRDFVVETLNDISLVMIHLSRFSEEIIFWSSDEAKFITLSDSFSTGSSIMPQKKNPDMAELIRGKTGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTVTGSLRIFEGMLASLTVNTDRLNETVHQDFSNATELADYLVEKDVPFREAHAIVGQIVYWCIQHDCYLLDVPLEKYQEFSSSIDDTIYSYLKPENCLKRRKSYGSTGQESVRHQIKVAKDLL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KISH_SCHPO
Sequence: MTAIFNFESLLFVILLTICTCTYLHRQFPALLEKRKEGVTMVFWKCARIGERASPYISLFCVFMALRFIFGSS
What is the function of this protein?
Involved in the early part of the secretory pathway.
What are the official names of this protein?
Protein kish.
What is the protein family that this protein belongs to?
Belongs to the KISH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: INCF_CHLTR
Sequence: MGDVMIQSVKTESGLVEGHRGICDSLGRVVGALAKVAKLVVALAALVLNGALCVLSLVALCVGATPVGPLAVLVATTLASFLCAACVLFIAAKDRGWIASTNKC
What is the function of this protein?
Inclusion membrane protein probably involved in early modification events of the chlamydial inclusion.
What are the official names of this protein?
Inclusion membrane protein F.
What are the subcellular locations of this protein?
Secreted. Host vacuole, host pathogen-containing vacuole, host pathogen-containing vacuole membrane; Multi-pass membrane protein. Note=Secreted, probably by a type III secretion system (By similarity). Localized in the inclusion membrane (By similarity).
Protein: FLPA_THEAC
Sequence: MQEKIRRKSSQPVYLYGMKNMLRIGNKLYTRTSKNKKVYGEDIIRFEHANYREWRPDRSKLAAAILKGLHNMPIGESSSILYLGASTGTTVSHVSDIAPSGRIYAVEVAYEPFSKLLDLAEQRDNIYPILEDANLPERYRFFVDHVDVIYQDISQRNQIAIFKRNMDEFQPRSAFLVLKTRSIASTEDAKTILRKTIEQLSSYNIREVIDLSPYDTDHYLILVDAKGVRR
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: YIDD_CUPNH
Sequence: MKPILLALLRIYKIALSPYLGSRCRFLPTCSDYARDAVIHHGAARGSWMAACRLCRCHPFAQGGYDPVPGTEADDTARPDTHAGRSVHAAAGHAPVAIRLPRP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RK20_PELHO
Sequence: MTRIKRGSIARRRRAKTRLFASGARGAHSRLTRLIAQQTIRALASAHRDRDKKKRDFRRLWITRINGVIRQNVLSYSYSQLITNLKKEQLLLNRKMLAQIAISNRNCLSIIYSAIIILETKEEGQK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y655_FRATT
Sequence: MAGHSKWANIKHKKAKEDAKRGKIFTKLIREITVAARLGGGDKDANPRLRAAIATALANNMSKDTIERAVVKGAGGDESANVEEVRYEGYGPGGVAIIVDCMTDNRNRTVGEVRHAFTKSGGNLGTDGSVAYMFTKRGIISFAPGVDEDALMEVALEAGAEDIITHEDGSIDVYTDPHDFSDIQEVLIEKGFNSENAEVTFDAETKAELDTETAEKVMALIDKLEDLDDVQNVYSNANFTQELIEQIG
What are the official names of this protein?
Probable transcriptional regulatory protein FTT_0655.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDX1_NEUCR
Sequence: MTSTSTTTNGDSFTVKAGLAQMLKGGVIMDVTTPAEARIAEEAGACAVMALERIPSDIRAAGGVARMSNPSMIKEIQAAVTIPVMAKARIGHVTECRILEQLGVDYIDESEVLTPADDTYHVQKDQFKAPFVCGCRNLGEALRRIKEGAAMIRTKGEAGTGDVVEAVKHIRTVNAEIAQAKAALASGGELAVAKMAREIGADVELLKKTAELGRLPVVNFAAGGVATPADAALMMEFGCDGVFVGSGIFKDAKTPEHALQRARAVVKAVANWNDYGALVEACIEHGEAMKGISNAGMKPEERMAGRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by pdx-2.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.  Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers.
What are the official names of this protein?
Probable pyridoxal 5'-phosphate synthase subunit pdx-1, PLP synthase subunit pdx-1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: RL11_MARMS
Sequence: MAKKVQAYIKLQVKAGQANPSPPVGPALGQHGVNIMEFCKAFNAKTQSLEPGLPTPVIITVYSDRSFTFETKSTPAAVLLKKAAGLKSGSPRPNTQKVGTVTRAQLEEIVVAKQADLTASNMDAAVRTIAGSARAMGLEVEGVN
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RS19_RICCK
Sequence: MARSIWKGPFVDGYLIKKVQKLMESGKSEMIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNEEMVGRKLGEFAPTRTFYGHGADKKVKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RECO_BACVZ
Sequence: MLTKCEGIVLRTNDYGETNKIVTLLTREHGKIGVMARGARKSASRLSAVSQPFLYGSFLMQRTSGLGTLQQGEMILSMRTIREDLFLTAYAAFIAELTDKGTEEKKPNPYLFELILESFKRLNDGTDPDVITFIVQMKMLGVMGLYPELNHCVHCKSGEGTFHFSIRDNGFICHRCFEKDPYRVPMSPQTARLLRLFYYFDIGRLGSVSLKQETKNEIKRVIDLYYEEYSGLYLKSKRFLDQMESMKNLLDENKS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: YIDD_ECO7I
Sequence: MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SXL_DROME
Sequence: MYGNNNPGSNNNNGGYPPYGYNNKSSGGRGFGMSHSLPSGMSRYAFSPQDTEFSFPSSSSRRGYNDFPGCGGSGGNGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKAAHFMSQMGVVPANVPPPPPQPPAHMAAAFNMMHRGRSIKSQQRFQNSHPYFDAKKFI
What is the function of this protein?
Sex determination switch protein which controls sexual development by sex-specific splicing.  Regulates dosage compensation in females by suppressing hyperactivation of X-linked genes.  Expression of the embryo-specific isoform is under the control of primary sex-determining signal, which depends on the ratio of X chromosomes relative to autosomes (X:A ratio).  Expression occurs in 2X:2A cells, but not in X:2A cells.  The X:A ratio seems to be signaled by the relative concentration of the X-linked transcription factors SIS-A and SIS-B.  As a result, the embryo-specific product is expressed early only in female embryos and specifies female-adult specific splicing; in the male where it is not expressed, the default splicing gives rise to a truncated non-functional protein.  The female-specific isoform specifies the splicing of its own transcript, thereby initiating a positive autoregulatory feedback loop leading to female development pathway.  The female-specific isoform controls the sex-specific splicing of transformer (TRA); acts as a translational repressor for male-specific lethal-2 (MSL-2) and prevents male-less (MLE), MSL-1 and MSL-3 proteins from associating with the female X chromosome.
What are the official names of this protein?
Protein sex-lethal.
Protein: DEOB_SALPA
Sequence: MKRAFIMVLDSFGIGATEDADRFGDVGSDTLGHIAEACAKGEADNGRKGPLNLPNLTRLGLVKAYEGSTGKIAAGMDGNADVIGAYAWAHELSSGKDTPSGHWEIAGVPVLFDWGYFSDHENSFPQELLDKLVKRANLPGYLGNCHSSGTVILDQFGEEHMKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTEGGYNIGRVIARPFIGDKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKQGHVVSVGKIADIYANCGITKKVKATGLDALFDATLKEMKEAGDKTIVFTNFVDFDSSWGHRRDIAGYAAGLELFDRRLPELMELVGEDDILILTADHGCDPSWTGTDHTREHIPVLIYGPKVKPGSLGHRETFADIGQTLATYFGTSPMDYGKNML
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP39_YEAST
Sequence: MPDETNFTIEDIEPRPDALRGLDTQFLQDNTALVQAYRGLDWSDISSLTQMVDVIEQTVVKYGNPNDSIKLALETILWQILRKYPLLFGFWKRFATIEYQLFGLKKSIAVLATSVKWFPTSLELWCDYLNVLCVNNPNETDFIRNNFEIAKDLIGKQFLSHPFWDKFIEFEVGQKNWHNVQRIYEYIIEVPLHQYARFFTSYKKFLNEKNLKTTRNIDIVLRKTQTTVNEIWQFESKIKQPFFNLGQVLNDDLENWSRYLKFVTDPSKSLDKEFVMSVFDRCLIPCLYHENTWMMYIKWLTKKNISDEVVVDIYQKANTFLPLDFKTLRYDFLRFLKRKYRSNNTLFNNIFNETVSRYLKIWPNDILLMTEYLCMLKRHSFKNSLDQSPKEILEKQTSFTKILETSITNYINNQIDAKVHLQTLINDKNLSIVVVELIKTTWLVLKNNMQTRKYFNLYQKNILIKNSVPFWLTYYKFEKSNVNFTKLNKFIRELGVEIYLPTTVMNDILTDYKTFYLTHSNIVTYESSIIDSNTFDPILYPELKMSNPKYDPVLNTTANVDWHKKTEWKEAGHIGITTERPQISNSIIECNSGTLIQKPISLPNFRNLEKINQVKINDLYTEEFLKEGK
What is the function of this protein?
Function prior to stable branch point recognition by the U1 snRNP particle to facilitate or stabilize the U1 snRNP/5'-splice site interaction.  Has a direct role in the assembly or function of a catalytically active spliceosome.
What are the official names of this protein?
Pre-mRNA-processing factor 39.
What is the protein family that this protein belongs to?
Belongs to the PRP39 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GBG2_BOVIN
Sequence: MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, G gamma-I.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RL25_METC4
Sequence: MSATKTLEAVARDRVGKGAARAVRRQGQIPAVIYGGNQAPQAIAIDLIRARTLIYAGGFKTTVFEIDAGGKKTRAIPRDYQLDPVSGVPLHVDFLRVVAGQTVTVDVPVHFVNEDQAPGIKQKGGTLNVALHTVSLEVAPDQIPDAIEVDLAGREIGDVIHASDLRLPAGTYTGEPTDTVANLLPPTVLGADVEAEEAAVAEAQSAESAEGKAEAEAEATNEKNKSEA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ATPA_ACIBC
Sequence: MQQLNPSEISALIKQRIGDLDTSATAKNEGTIVMVSDGIVRIHGLADAMYGEMIEFDGGLFGMALNLEQDSVGAVVLGNYLSLQEGQKARCTGRVLEVPVGPELLGRVVDALGNPIDGKGPIDAKLTDAVEKVAPGVIWRQSVDQPVQTGYKSVDTMIPVGRGQRELIIGDRQTGKTAMAIDAIIAQKNSGIKCVYVAIGQKQSTIANVVRKLEETGAMAYTTVVAAAAADPAAMQYLAPYSGCTMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVSAEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETSLFNAGIRPAVNAGISVSRVGGSAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDEATRKQLEHGQRVTELMKQKQYAPYSIADQAVSVYASNEGYMADVEVKKIVDFDAALIAYFRSEYAPLMKQIDETGDYNKDIEAAIKAGIESFKATQTY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CTU2_DROER
Sequence: MCSIGEDDFGDEGAAHAMVVEALPLGIVLSPGNCSKCDVNSGELYKLNFRAAECRECFLTYARHKFRAALGAAKILPRNAEVLLVLDGSAKSLVLLDMLHFAQTQNQFKRLHCNARVVYVEEQQVQDRDPVDLEALLSLSVQYAPFDFYVIELGQGCSLQRIKDYSPSLKANNELIHKLQKLQSLTARQDYLQQQRKNLICSVAQSLQCTHVFEPNISVDLATQLLTAIALGRGASAALDVALLDDRLSGDVKLLRPLKDLSEQEIQFYIHAQRLKPLFQSGSHYGMERGPTASLQNLTSAFVANLQHNYASTVSTVFRTGDKIAVNSDPEQATCVHCQSALDSELSDTLLAIEYSRSVSEAGVSLYKNGQDLESLAKKRLEMQDGLCHACRAIQAELESGNLL
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QRFP_BRAFL
Sequence: MGVRVMRSRICVIGLLVLMLTQSEAYSFREKSWRTSPYYRQYGGYFRRRDGGDQAPSFTSTGNGEDVSNGLDDDAGIYLSDQAGDDGISPADKRSAMLQQLAQQLKNRPREKGGFTFRFGKRESRRSFGSD
What is the function of this protein?
Ligand for the G-protein coupled receptor QRFPR.
What are the official names of this protein?
QRFP-like peptide.
What is the protein family that this protein belongs to?
Belongs to the RFamide neuropeptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS4_VARPS
Sequence: MLLIPAIDLKDGHCVRLKQGDMDQSTIFSEDPAAMARKWVEAGARRLHLVDLNGAFAGKPQNHAAIKAILREVGDDIPVQLGGGIRDLDTIERYIDDGLRYVIIGTAAVKNPGFLKDACVAFGGHIIVGLDAKDGKVATDGWSKLTGHEVADLGKKFEDYGVESIIYTDIGRDGMLSGINIDATVKLAQALTIPVIASGGLSNMADIDQLCAVESEGVEGVICGRAIYSGDLDFAAAQARADELAGA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASR_ECO27
Sequence: MKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNAKAEQKAPEQKAQAAKKHARKHSHQQPAKPAAQPAA
What is the function of this protein?
Required for growth and/or survival at acidic conditions.
What are the official names of this protein?
Acid shock protein.
What is the protein family that this protein belongs to?
Belongs to the Asr family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HUTH_DICDI
Sequence: MSTTDKIVYLNGNTLKIEDLINIGYRGYNVSITQEVEELIQKGRNVIDDILKSEKTVYGINTGFGLFSDVIIPPDQVKMLQVNLIRSHSSGVGTPLTPERTRMLLALRINVLTKGYSGITLETVKRAIKILNGNCLPLVPEKGTVGASGDLAPLSHLALGMMGEGKMYDFGDSGNTFTSNLDVDVLEYRNFKFSPANEILKRQNLTPIELNAKEGLALINGTQLITSLGAEAVYRCKVLAETANIITAMTFEALKGLTAAYHPLIHAARPHSGQGRVAAFLRSVLHSDQYPSEITLANKDTKKVQDSYTLRCVPQVHGIVFDTIDFVQGIINTEMNSATDNPMVFDTDELCGTISGGNFHGEYPAKALDYLTIGIHELSNISERRLERLVNSQLSDGLPSFLVNGGGLNSGFMIAHCTSAALVSENKVLVHPSSADTISTSSAKEDHVSMGGWSARKCLNVVENVENVLAIELLAACQGLDFRRPLKTTEPLEAVYQLVRSKVTFMDKDRFIQPDIEEVYKLIRSGQVLNVVNSILNKK
What are the official names of this protein?
Probable histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_ECO45
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.