PharMolix/UniProtQA huggingface dataset:
Protein: BOREA_DROME
Sequence: MPRTKIPKNSKRNREVANREEKVRLYELKMDSRLISIDSLETKFLSAVDHQVKTLLGQVQKELANLKMPEVLRLFEELDRFSDFKASDQTQLLASMSMSGSAIEGHAPSATGSRNDEEDSSIGASGGSILAAHTGSLLRSTKAMRTPGPLHSARARRARRSRSACGDLNILHSAKPPSISSSSSSSRNSRSKLRTPMASRAKAFSADRTPLKQKQMRSGSPTTPPMAFLRYPKPGEVALSKYGSPMVAQVMPDKFANVNIPIRNGVLSLRPKKLDADEVESNLLENLDEDTLNQIKTLHENLQMIVNKASQAVFK
What is the function of this protein?
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of embryonic mitosis.  The CPC complex has essential functions at the centromere for ensuring sister chromatid cohesion, recruitment of the CPC to kinetochores, and chromosome alignment and segregation.  There is no function in meiotic histone phosphorylation or spindle formation.
What are the official names of this protein?
Borealin, Aurora borealis protein, Borealin-related.
What is the protein family that this protein belongs to?
Belongs to the borealin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with and is required for the correct localization of the CPC components Aurora B kinase and Incenp in mitotic cells. Is absent from spermatocytes undergoing meiosis.
Protein: CBIN_SALDC
Sequence: MKKTLMLLAMVVALVILPFFINHGGEYGGSDGEAESQIQAIAPQYKPWFQPLYEPASGEIESLLFTLQGSLGAAVIFYILGYCKGKQRRDDRA
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiN, Energy-coupling factor transporter probable substrate-capture protein CbiN, ECF transporter S component CbiN.
What is the protein family that this protein belongs to?
Belongs to the CbiN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y447_TREPA
Sequence: MNNLIKAYAAGVMSAAFLFGSEGRVRSESDRVRGEDPWHLLQWAQVVYEREEFGDTLRYAQRARALRREQVEHQCRVLLRARTRAESAGIPETLSDLYALLKSRGETDACEVLDAIFLTHAPHVFQNSVSKLLQWLKDSAAFPEAELLLGKVFEGEGEYAQALQHYRNAWDTRAQLVVPDARFDIIYAMANVSRLLSQQDEREKYLLLVLSEDPLYSAREVWGKTLHAMLRTIRSSNTVEKFFKLYRHRNVLALRAYQELTEMYVRTDNIERALPVSVLAADIAISALDSFLQKIELTYQYKDLADLFLRTGSHPTILKWANEHGVWQTLLHFADLLYKKGLHAQARDMYYNLAEKCPAFEYARRAAYKLSLTL
What are the official names of this protein?
Uncharacterized protein TP_0447.
Protein: TILS_LEGPH
Sequence: MLVTRPLLSPEWVARLKQFKKLIVGFSGGLDSTVLLHVLASTPPLSNQLLAVHINHGISGNSLNWQRHCEQLCLDLGIAFIAKAIEFDRSANVEEAARNARYDFFSSLLEDNDCLVLGHHLDDQAETVLLQLFRGAGVDGLAAMQECSNLGAGQLARPFLTCPRVELEHYARIHELKWIEDESNQDTKYSRNYLRHRVMPLLLEKWPGVAGNISRAATHCQQAKANLEVLAIKDCPDLLNATDHLLIEPIKGLEFERITNVLKFWLKKNRIQLPSSKTFHRIIHEIIFAKLDAMPTVSWNQIQVRRFQQHLYLLKADQINLPKAIKWQQFPASLTYPDADIKLSAVKAQKGLMIPKDAQIEIRFRKGGEEIYWHGQTKHLKKLFQEWQIPPWVRDRVPLVYINDQLACVVGYAVSDLFFTTNPLEAWSIVNNS
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_DESAL
Sequence: MKKDIHPKYETTVIRCACGATVEAGSTVDDLTVEICSQCHPFFTGKQKLVDTAGRIERFRRKYAKFNQAQEAKQDQ
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: HIS7_SULIY
Sequence: MARNANITRETKETKIEVFLDIDRKGEIKISTPVPFFNHMLITLLTYMNSTATVSATDKLPYDDHHIIEDVAITLGLAIKEALGDKRGIKRFSHQIIPMDEALVLVSLDISNRGMAFVSLNLRRSEIGGLATENIPHFFQSFAYNSGVTLHISQLSGYNTHHIIEASFKALGLALYEATRIVDNEIRSTKGVI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_COCIM
Sequence: MASKSQVPYEDRARDHPNPLARRLFQIATEKQSNVAVSADVTTTKELLDLADRLGPYMVVLKTHIDILADFSAETITGLQSLSQKHNFLIFEDRKFVDIGNTVQKQYHGGALHISEWAHIVNATVLPGPGIIDALAQVASAPDFPHASDRGLLILATMTSKGSLATGQYTELSVELARKYKGFVLGFVASRSLEGVETAGKADDEDFVLFTTGVNLASKGDALGQQYQTPESAIGGGADFIISGRGIYAAPDPVDAARRYQKAGWDAYLKRVGR
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: MAFA1_TOXGM
Sequence: MWRIWRCRLSFLFATGCLLGALTAGLGSQMSDSVGRNVQAPAGVADASQEAGDVVEERTERTEQQVFALGPPRRHSSESLFPRNASVTARRRRNRRIALIATAVGVAVILAALYVLRRRRAQPPQEPEPPTRLRTPRPRAPSGQQQPSESEPPAGVPMTPGFLTLPFTCLRDTKVTFFGPSGRQHGFTALYDPSPNKRVATVDAGTNRLFIGGGGMNGEFANTIIEEARRNRIPLTATELSAESQEIQERLLRDAERRPGTLVEIDSGRFSRVFARSFAYVAIVPNTVWDESETGKNVGATFLHILKPEVTPHGNQMNDVMLYTVAPLGNASDSAYNLAYKATMLGIVGAVSEYNKTPWGEVKPVEAIRLPLLGAGHFRGRRGLHSIGRANAVAVEAAITRFDPRVELQFMYEPSDAALRGLMESERTYTFPQGD
What is the function of this protein?
During host cell infection by tachyzoites, does not play a role in tethering the parasitophorous vacuole to the host mitochondria, probably because it does not bind host mitochondrial import protein TOMM70.
What are the official names of this protein?
Mitochondrial association factor 1 form a1, MAF1ME49a1 allele.
What are the subcellular locations of this protein?
Parasitophorous vacuole membrane; Single-pass type I membrane protein.
Protein: SNQ2_YEAST
Sequence: MSNIKSTQDSSHNAVARSSSASFAASEESFTGITHDKDEQSDTPADKLTKMLTGPARDTASQISATVSEMAPDVVSKVESFADALSRHTTRSGAFNMDSDSDDGFDAHAIFESFVRDADEQGIHIRKAGVTIEDVSAKGVDASALEGATFGNILCLPLTIFKGIKAKRHQKMRQIISNVNALAEAGEMILVLGRPGAGCSSFLKVTAGEIDQFAGGVSGEVAYDGIPQEEMMKRYKADVIYNGELDVHFPYLTVKQTLDFAIACKTPALRVNNVSKKEYIASRRDLYATIFGLRHTYNTKVGNDFVRGVSGGERKRVSIAEALAAKGSIYCWDNATRGLDASTALEYAKAIRIMTNLLKSTAFVTIYQASENIYETFDKVTVLYSGKQIYFGLIHEAKPYFAKMGYLCPPRQATAEFLTALTDPNGFHLIKPGYENKVPRTAEEFETYWLNSPEFAQMKKDIAAYKEKVNTEKTKEVYDESMAQEKSKYTRKKSYYTVSYWEQVKLCTQRGFQRIYGNKSYTVINVCSAIIQSFITGSLFYNTPSSTSGAFSRGGVLYFALLYYSLMGLANISFEHRPILQKHKGYSLYHPSAEAIGSTLASFPFRMIGLTCFFIILFFLSGLHRTAGSFFTIYLFLTMCSEAINGLFEMVSSVCDTLSQANSISGILMMSISMYSTYMIQLPSMHPWFKWISYVLPIRYAFESMLNAEFHGRHMDCANTLVPSGGDYDNLSDDYKVCAFVGSKPGQSYVLGDDYLKNQFQYVYKHTWRNFGILWCFLLGYVVLKVIFTEYKRPVKGGGDALIFKKGSKRFIAHADEESPDNVNDIDAKEQFSSESSGANDEVFDDLEAKGVFIWKDVCFTIPYEGGKRMLLDNVSGYCIPGTMTALMGESGAGKTTLLNTLAQRNVGIITGDMLVNGRPIDASFERRTGYVQQQDIHIAELTVRESLQFSARMRRPQHLPDSEKMDYVEKIIRVLGMEEYAEALVGEVGCGLNVEQRKKLSIGVELVAKPDLLLFLDEPTSGLDSQSSWAIIQLLRKLSKAGQSILCTIHQPSATLFEEFDRLLLLRKGGQTVYFGDIGKNSATILNYFERNGARKCDSSENPAEYILEAIGAGATASVKEDWHEKWLNSVEFEQTKEKVQDLINDLSKQETKSEVGDKPSKYATSYAYQFRYVLIRTSTSFWRSLNYIMSKMMLMLVGGLYIGFTFFNVGKSYVGLQNAMFAAFISIILSAPAMNQIQGRAIASRELFEVRESQSNMFHWSLVLITQYLSELPYHLFFSTIFFVSSYFPLRIFFEASRSAVYFLNYCIMFQLYYVGLGLMILYMSPNLPSANVILGLCLSFMLSFCGVTQPVSLMPGFWTFMWKASPYTYFVQNLVGIMLHKKPVVCKKKELNYFNPPNGSTCGEYMKPFLEKATGYIENPDATSDCAYCIYEVGDNYLTHISSKYSYLWRNFGIFWIYIFFNIIAMVCVYYLFHVRQSSFLSPVSILNKIKNIRKKKQ
What is the function of this protein?
Could be an ATP-dependent permease.  Confers hyper-resistance to the mutagens 4-nitroquinoline-N-oxide (4-NQO) and triaziquone, as well as to the chemicals sulphomethuron methyl phenanthroline when present in multiple copies.  Exhibits nucleoside triphosphatase activity.
What are the official names of this protein?
Protein SNQ2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y4462_PSEAB
Sequence: MMKGGMAGLMKQAQQMQEKMQKMQEELANAEVTGQSGAGLVSVVMTGRHDVKRVSLDDSLMQEDKEILEDLIAAAVNDAVRKIEQNNQEKMSGFTSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein PA14_44620.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LYSC_CRAFA
Sequence: KIYTRCELAAAMKRYGLDNYQGYSLGNWVCAARYESNYNTQATNRNSDGSTDYGILQINSRWWCNDGKTPGTRNLCHISCSALMGADIAPSVRCAKKIVSDGNGMNAWVAWRKHCKGTDVSKWIKDCKL
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYV_SHIBS
Sequence: MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DB119_CANLF
Sequence: MKFFLFFVILLAMEPVISGKHHILRCMGNTGICRPSCRKTEQPYLYCLNYQSCCLQSYMRISISGREEKDDWSQQNRWPKIS
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 119, Defensin, beta 119.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3536_METJA
Sequence: MAYWLCITNEDNWKVIKEKKIWGVAERYKNTINKVKVGDKLIIYEIQRSGKDYKPPYIRGVYEVVSEVYKDSSKIFKPTPRNPNEKFPYRVKLKEIKVFEPPINFKELIPKLKFITNKKRWSGHLMGKAMREIPEEDYKLIVGN
What are the official names of this protein?
UPF0310 protein MJECL36.
What is the protein family that this protein belongs to?
Belongs to the UPF0310 family.
Protein: HS71L_BOVIN
Sequence: MAAAKGTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRKFNDPVVQSDMKLWPFQVINEGGKPKVMVSYKGEKKAFYPEEISSMVLTKMKETAEAFLGYTVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKAGQGERHVLIFDLGGGTFDVSVLTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKANKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSAVSDEGLQGKISESDKKKILSKCNEVLLWLEANQLAEKDEFDHKRKELEQVCNPIITKLYQGGCTGPSCGTGYTPGRAATGPTIEEVD
What is the function of this protein?
Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes.  Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation.  This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones.  The affinity for polypeptides is regulated by its nucleotide bound state.  In the ATP-bound form, it has a low affinity for substrate proteins.  However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins.  It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release.  Positive regulator of PRKN translocation to damaged mitochondria.
What are the official names of this protein?
Heat shock 70 kDa protein 1-like, Heat shock 70 kDa protein 1L.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: LPXH_STRMK
Sequence: MTTLFISDLHLDPSRPEITDLFLRFLREQAPGADALYILGDLFEAWIGDDTPSPAADAVADALKVLSDSGVPVYFIRGNRDFLLGEDYARRAGLRILPDPCMIDLYGRPVLLQHGDLLCTDDIPYQQFRAQTRDPAFQAQFLSQPLAARIAFAQKAREASQARQSEMKQGDRAQFETVTDVAPSEVDATFARHGVDTMIHGHTHRPAIHSLQAGGRACTRIVLGDWYEQGSVLRVDAGGWSLDTLARE
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IST1_BOVIN
Sequence: MLGSGIKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGGGGFTAPVGGPDGTVPMPMPMPMPSPNTPFSYPLPKGPSDFNGLPVGTYQAFPNIHPPQIPATPPSYESVDDINADKNVSSTQIVGPGPKPEPPAKPASRLTETYDNFVLPELPSVPDTLPTASPGANTSASEDIDFDDLSRRFEELKKKT
What is the function of this protein?
ESCRT-III-like protein involved in cytokinesis, nuclear envelope reassembly and endosomal tubulation (By similarity).  Is required for efficient abscission during cytokinesis (By similarity).  Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (By similarity).  During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing (By similarity).  Recruited to the reforming nuclear envelope (NE) during anaphase by LEMD2 (By similarity).  Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST (By similarity).
What are the official names of this protein?
IST1 homolog, Charged multivesicular body protein 8, CHMP8.
What is the protein family that this protein belongs to?
Belongs to the IST1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Nucleus envelope. Note=Localizes to centrosome and midbody of dividing cells. Colocalized with SPART to the ends of Flemming bodies during cytokinesis. Localizes to the reforming nuclear envelope on chromatin disks during late anaphase.
Protein: PUR9_BARQU
Sequence: MGVVAKKFPIPDLHRVRRVLLSVSDKTGVVAFAQALHAYSVELISTGGTAKVLMDAGLPVKDVAEVTGFPEIMDGRVKTLHPLIHGALLGVRQDPSHAVAMEKHGIHGIDLLVVNLYPFEKTSQSGADGQTILENIDIGGPAMIRAAAKNHAYTGVVTAVSDYDFVLAELKQHDGCLSFSMRRQLAMRAYAHTAAYDAAIATWFAQDLKIETPSWQSFSGYLENVMRYGENPHQQAAFYRNNEKRFGVATAKLLQGKALSYNNMNDTDAAFELVAEFDPQKTTAVALIKHANPCGVAEGKSLKEAYLKALMCDNVSAFGGIVALNQPLDEECAEEIVKIFTEVIIAPDATIAAREIIARKKNLRLLTTGGLPDPRCGGLVAKTLAGGILVQSRDNMVVDDLNLQVVTKRAPSQDEMRDLQFAFRVVKHVKSNAIVYAKNSATVGIGAGQMSRIDSAKIAARKAEESAQRAGLTESPTRGSVVASDAFFPFADGLLAAVEAGATALIQPGGSMRDEEVIAAADAHGLAMVFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: MCA1_KLULA
Sequence: MYPGRAKPTYNNQQAQQAQSQVGYQTGYSNAQPQQQYYTAPQQQNVSGSSMSFQHQFYPPPNQSPPQYNTGQYARPAAPPPGQQNYRNDIQQNHASGTVNGPSGYQQPQAMYKPPSQVQHTGPNNQVAYQYSQCTGRRKALLIGINYFGSANELRGCINDSHNMFNFLTQRYGYKAEDIVMLNDDTTDPVRVPTKANMLRAMQWLVKDARPNDALFFHYSGHGGQTEDLDGDEEDGMDDVIYPVDFQMAGHIVDDDMHAIMVSPLQPGVRLTALFDSCHSGTVLDLPYTYSTKGVIKEPNMWKDVGSSGLQAAMAYATGNTTSLVSSLGNVFTTITKSNNNVDRERVKQIKFSPADVIMFSGSKDNQTSADATENGQNTGAMSWAFLTVLSKQPQQSYLSLLQNMRAELSSKYTQKPQLSCSHEIDTNLQFLL
What is the function of this protein?
Involved in cell death (apoptosis).
What are the official names of this protein?
Metacaspase-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: DDL_COXBU
Sequence: MAEKLHISVLCGGQSTEHEISIQSAKNIVNTLDAAKYLISVIFIDHVGRWYLIDQPEMFLAHSPDHLVKEGSARPITIAFGDAAKPWQSLNGDGRRYSADCVFPMVHGTQGEDGALQGLLELLNLPYVGANVQSSAVCMEKDLTKTVLRAGGIPVVDWHTLSPRDATEGVYQRLLDRWGTSELFVKAVSLGSSVATLPVKTETEFTKAVKEVFRYDDRLMVEPRIRGREIECAVLGNGAPKASLPGEIIPHHDYYSYDAKYLDPNGATTTTSVDLSESVTKQIQQIAIDAFKMVHCSGMARVDFFVTPNNKVLVNEINTIPGFTNISMYPKMWEASGLPCPNLLDQLIELAIDRHQEQQKLIRCYEVKARSL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS2_STRPB
Sequence: MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDARQLVALKNKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKAHLEKIIIGYNFQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACDKRGVDVVISDVWANGGAGGRELAEKVVALAEQDNQFRFVYNEDDSIETKLTKIVTKVYGGKGIKLTPTAKRELAELERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFIVTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 2, Formyltetrahydrofolate synthetase 2, FHS 2, FTHFS 2.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: TRP7_RHYMA
Sequence: VPASGFFGMR
What is the function of this protein?
Myoactive peptide.  Increases the amplitude and frequency of spontaneous contractions and tonus of hindgut muscle.
What are the official names of this protein?
Tachykinin-related peptide 7, LemTRP 7.
What are the subcellular locations of this protein?
Secreted.
Protein: LUTA1_BACCZ
Sequence: MKVTLFVTCLVDMFETNVGKATVEVLERLGCEIEFPEAQVCCGQPAYNSGHVEAAKEAMKHMIETFEDAEYIVTPSGSCATMFHEYPHVFKDDPKWAKRAQKVADKTYEFTQFIVDVLKVTDVGASLPGIATIHKSCHMTRMLGVTEAPGILLSNVKGLTVRELPNVQNCCGFGGTFSVKMTPISEQMVDEKVDSAMETGADYLIGADCGCLLNIGGRIERLGKEIKVMHIAEVLNSRS
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A 1.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: TRMD_HAES1
Sequence: MWIGIISLFPEMFKAITEYGVTGRAVRQNLLEIQYWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHCAKSVAGDGVKVIYLSPQGRKLDQNGVQELARNQKMIFVCGRYEGIDERLIETEIDEEWSIGDYVLTGGELPAMTLIDAVARFVPCVLGKQASAQEDSFAEGLLDCPHYTRPEQLNGLTVPPVLMSGNHEEIRKWRLKQSLQRTWLRRPELLESLALTDEQSKLLSQIKQENS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_BRUMB
Sequence: MSIFRFFTRQQASAPQARERLQVLLAHERASYGGQSDLVAVLREEILAVIAKHIKVDREKVSVKMDRGDQVSTLEVDIELPLTAKKGRAA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: DC122_HUMAN
Sequence: MAQQQTGSRKRKAPAVEAGAGSSSSQGLAAADGEGPLLPKKQKRPATRRRLVHYLKGREVGARGPAGLQGFEGELRGYAVQRLPELLTERQLDLGTLNKVFASQWLNARQVVCGTKCNTLFVVDVQSGHITRIPLMRDKEAGLAQAHQGCGIHAIELNPSKTLLATGGENPNSLAIYQLPTLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDMFNGSIAWHSEVGLPVYAHIRPRDVEAIPRASTNPSNRKVRALAFSGKNQELGAVSLDGYFHLWKARSTLSRLLSIRLPYCRENVCLTYCDELSLYAVGSQSHVSFLDPRQRQQNIRPLCSREGGTGVRSLSFYQHIITVGTGHGSLLFYDIRAQKFLEERASSSLDSMPGPAGRKLKLACGRGWLNQDDVWVNYFGGMGEFPNALYTHCYNWPEMKLFVAGGPLPSGLHGNYAGLWS
What are the official names of this protein?
DDB1- and CUL4-associated factor 12-like protein 2, WD repeat-containing protein 40C.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF12 family.
Protein: METI_BACSU
Sequence: MSQHVETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAIQTIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDNTFYTPVLQRPLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGEEMFQHQNAIGAVLPPFDSWLLMRGMKTLSLRMRQHQANAQELAAFLEEQEEISDVLYPGKGGMLSFRLQKEEWVNPFLKALKTICFAESLGGVESFITYPATQTHMDIPEEIRIANGVCNRLLRFSVGIEHAEDLKEDLKQALCQVKEGAVSFE
What is the function of this protein?
Catalyzes the formation of L-cystathionine from O-acetyl-L-homoserine and L-cysteine.  Cannot use O-succinyl-L-homoserine as substrate.  Also exhibits O-acetylhomoserine thiolyase activity, catalyzing the synthesis of L-homocysteine from O-acetyl-L-homoserine and sulfide.
What are the official names of this protein?
Cystathionine gamma-synthase/O-acetylhomoserine (thiol)-lyase, CGS/OAH thiolyase, O-acetylhomoserine sulfhydrylase, OAH sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC105_RAT
Sequence: MPVLLPSTDRDQDSRVGAPEWHQAAKATSRKAHLLTDRCGKEAVTMWQPKDSVLDPNVAHHLGRAAYMEPWRFRVEMLKGGGTVEKPPPGEGVTLWKGKMKPPAWYARLPLPMHRDARAQQTAEVVHAHARGARLTAARLGRAQHQINGQLRLLLRQREATDRRLSEVRKGLLINEQSVKLRGYRPKCEKIPDKADSMLVWEREELKSMKRKMEKDMERSEALLKALASCRDTLDFYCQERLQAVGLMNQPLDKVLEQAGRHSWVDITRPPTPRTQGLKTPPPDPVGAYTPACAKALFEAKRLLMESKDILAELAKNEVDIQNQQQEISDRVCNSLAQKMRETLELKERMTMTLGLMRGTIHRCMKFNQEMYVTRGLIKGPLLKRDLEAREKLNRPLVRMYQRHVGTQLPEATRLAQGTDLLTRHNLQMEKNLKELRTTHDNLAWSLNCKKIGHDVDYDVVRLRLRQLHPHVCYEQAKRLINDWDPRTPPPCSRTNTSSK
What are the official names of this protein?
Coiled-coil domain-containing protein 105.