PharMolix/UniProtQA huggingface dataset:
Protein: COG6_YEAST
Sequence: MDFVVDYQTYAMADTATPELPEPEPRLNLTSDAQSQPTGKLDLQFKLPDLQRYSNNNATLPVDNDGAGSKDLHKKMTHYAMSSIDKIQLSNPSKQLGQNSQDEKLSQQESQNFTNYEPKNLDLSKLVSPSSGSNKNTTNLVLSNKLSKILNNYTLINYQATVQLRKSLKVLEENKERLSLDEQKLMNPEYVGTLARRALRTDLESQLLKEHITVLEEFKPIIRRIKRLSSSVEKIQRTSEKLLSNETNEVPTNNVVLQEIDQYRLKAEQLKLKKKILLSIRDRFTLNQVEDDVITNGTIDNIFFEVVKKVINIKDESSFLLTLPNLNAGNALIMGVNEILEKTNKKIFNYLIDFLYSFESSSNLLNDHGTTEQESLNIFRKSLVFLSSDLELFNELLKRVTTLRSKSILDEFLSQFDMNSTTSKPIILSAHDPIRYIGDVLASVHSIIANEADFVKSLFDFQDEDLKDTPISILQQNKTFLKGIDNKLLNDIIQSLSNSCRIRIEQIVRFEENPIINFEIVRLLKLYRVMFERKGIQDDSSIINNLKSLEDISKNRIIGYYEDYMKQTVMAETKNSSDDLLPPEWLSEYMNKLVELFEIYEKTHAAEDEESEDNKLLSSKNLQTIVEQPIKDVLLKQLQTSFPLAKKNEKEKASLLTIEINCFDLIKSRLQPFEGLFAQDDDSRKITIWVCDKLKEYTKQMLTLQIKFLFENTGLDLYSNLVNMIFPVDSVKDELDYDMYLALRDNSLMELDMVRKNVHDKLNYYLPQALTDVQGNLLFKLTSPMIADEICDECFKKLSLFYNIFRKLLIHLYPNKKDQVFEILNFSTDEFDMLIGIDH
What is the function of this protein?
Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking.  COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 6, COG complex subunit 6, Complexed with DOR1 protein 2, Component of oligomeric Golgi complex 6, Protein SEC37.
What is the protein family that this protein belongs to?
Belongs to the COG6 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: MURQ_GLOC7
Sequence: MNNLEERGHLLTEQINPNSQNLDQLSSLELVELFNAEDAQTLKAIAGAKLELAKAIEVISEALRQGGRLFYVGAGTSGRLGVLDAAECPPTFCTPPEMVQGIIAGGAQALIRSSEDLEDKLEDGASIIAQREITPLDVVVGITAGGTTPFVHGALMAAKTRRATTIAISCVPVEQVSIEADIDIRLLTGPEILAGSTRLKAGTVTKMALNILSTGAMVQLGKVYGNRMIDVAVTNRKLHDRALRIIQDLTDLNRTEAGSLLERSGRQVKLALLMHSLGVDAETGAHLLATHHGNLRAALNSALLKD
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: SPRR1_PIG
Sequence: MSSQQQKQPCTPPPQPQQQQVKQPCQPPPQEPCVPKTKEPCHPKVPEPCQPKVPEPCQPKVPEPCHPKVPEPCQPKVPEPCPSPVIPAPAQQKTKQK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.  It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase.  All that results in the formation of an insoluble envelope beneath the plasma membrane.
What are the official names of this protein?
Cornifin, SPRP, Small proline-rich protein I, SPR-I, Small proline-rich squamous cell marker.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_ASPOR
Sequence: MAETPELEPHNAFDTILTLDFGSQYTHLITRRLRELNVYSEMLPCTQKLADLKFKPAGVILSGGPYSVYEEGAPHVDPAYFDLGVPILGICYGLQEIAYRLDSTNVIAGTSREYGLAQLKAKKVGGHVDHLFDGLEDEFNVWMSHGDKLGKLPEGFHTIATTPNSEYAGIAHETKPIYGLQLHPEVTHTQNGTKLLKNFAVNICGCKQNWTMARFVDQEIARIRKLVGPTGQVLGAVSGGVDSTVAAKLMKEAIGDRFHAVLVDTGFMRLNECEQVKQTLAEHLGINLIVADASQVFMEGLKGISDPEQKRKFIGNKFIDVFEEEAKKIEDAAAHSETAGKIGFFLQGTLYPDVIESISFKGPSATIKTHHNVGGLPKRMTEGQGLKLIEPLRELFKDEVRDLGRQLGIAHEMVMRHPFPGPGIAIRILGEITPERVEMARKADHIFISMIREAGLYDKIGQAFAALDPSRAVGVMGDKRVYENIVLLRAVETTDFMTAIAYPFEHEFLTRVSTRIVNEVSGVCRVAYDYTSKPPGTIELE
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_ECO5E
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: XPT_CLOD6
Sequence: MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKERFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTKAREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQAGGALLKANDVRLESLAVVESIDNGTVKFR
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLD2_DANRE
Sequence: MLPRPYIFSHNDGPSSHLFQHVLPHNVSQQQRIEAHLNSTNNFIGPPMNAPRFIPTYQWTPVELSDVACSPNGPMGNNRKRRIQDNSDINLKRQRFSCPSPHNQSARNSNFTSQPVTRPVTGREVTCPTCSSATFIPGGCVPSLGETCHQNAFSPSSVKDKLSQQILNLFFACEQQSDDLEKKESCRAALQTDIQKIFPCAKVFLGGSSLNGFGSRSSDADLCLVIEEGPVNHRKDAVYVLSLVRKLLYKLSYIEKPQLIRAKVPIVKFRDRISGVEFDLNFNNTVGIRNTFLLRTYAFVEKRVRPLVLVIKKWANHHCINDASRGTLSSYTLVLMVLHYLQTLPEPVIPCLQRDYPTCFDPKMDIHLVPSGPSDIPAFVSRNQSSLGDLFLGFLRYYATVFKWDKQVISVRMARTLPKSNCKEWKDKFICVEEPFNRTNTARAVHERMKFEAIKAAFIESHRLLQLRKDLNFILPKSKQMARPQTAPR
What is the function of this protein?
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail.  In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs.  May not play a role in replication-dependent histone mRNA degradation (By similarity).
What are the official names of this protein?
Poly(A) RNA polymerase GLD2, PAP-associated domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family. GLD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLJA_SALAE
Sequence: MECIAVNDISYGREAEIWPRDYSMLARRVQFLRFNDILVRLVSNNARIITGYIAKFNPRENLILASDKPKGNKRIEVKLESLAILEELSGNDAFNLSLVPADEFNLQQYTPSRRDYFSICNKCYKQGVGIKIYMKYGQVLTGKTTGVNACQVGVRTSNGNHMQVMFDWVSRITSSDYAE
What is the function of this protein?
Transcriptional repressor of the FliC phase-1 flagellin.
What are the official names of this protein?
Repressor of phase 1 flagellin gene.
Protein: METXA_LEPBL
Sequence: MNESGSIGIIETKYAEFKELPLKNGSVLSPVVIAYETYGTLSPSKNNAILICHALSGDAHAAGYHSESDKKPGWWDDYIGPGKSFDTNQYFIICSNVIGGCKGSSGPLSIHPKTGTPYGSRFPFVSIQDMVKAQKLLVEFLGIDKLFCVAGGSMGGMQALEWSIAYPDSLLNCIVMASTAEHSAMQIAFNEVGRQAILSDPNWNNGLYNENSPRKGLALARMVGHITYLSDDKMREKFGRNPPRGNILTTDFAVGSYLIYQGESFVDRFDANSYIYVTKALDHYSLGKGKELTAALSTATCRFLIVSYSSDWLYPPAQSREIVKSLEAADKRVFYLELQSGEGHDSFLLKNPKQIEILKGFLENQSSP
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPM2_DROME
Sequence: MDAIKKKMQAMKLEKDNAIDKADTCENQAKDANSRADKLNEEVRDLEKKFVQVEIDLVTAKEQLEKANTELEEKEKLLTATESEVATQNRKVQQIEEDLEKSEERSTTAQQKLLEATQSADENNRMCKVLENRSQQDEERMDQLTNQLKEARMLAEDADTKSDEVSRKLAFVEDELEVAEDRVRSGESKIMELEEELKVVGNSLKSLEVSEEKANQRVEEFKREMKTLSIKLKEAEQRAEHAEKQVKRLQKEVDRLEDRLFNEKEKYKAICDDLDQTFAELTGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.  May also regulate motor systems required to maintain nuclear integrity and apico-basal polarity during embryogenesis.
What are the official names of this protein?
Tropomyosin-2, Tropomyosin I.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: TXBS1_BRASM
Sequence: MNTIQVIIFAVVLVLTVTVGQADEDSAETSLLRKLEEAEAAMFGQYLEESKNSREKRCIGESVPCDKDDPRCCREYECLKPTGYGWWYASYYCYRKKSG
What is the function of this protein?
Has minor, but significant effects on the Para/tipE insect sodium channel.
What are the official names of this protein?
Omega-theraphotoxin-Bs2a, Omega-TRTX-Bs2a, Brachypelma smithi toxin 1, Bs1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 08 (Ltx-4) subfamily.
Protein: EFTS_ONYPE
Sequence: MKITAEMIKDLRQKTHAGMKECHKALQQTEGNIEKAIVFLREKGIIKAAQKQGRATSEGITNIVFDGNNAFLYEINSETDFVSKNEHFQQLVKVLGEIILKNQLSNAKDLLAFNYQNKTVQELLLEKTSVLGENITLKRVLKVTKKPQESFGTYKHQGGRISVLVVLKNDCPSVSEDIAMHIAASKPQFLTPDKVDPTFLAEEKKILHKQTAKELSDKPAQMIEKIVENRLGKMLKDMCLSEQPFVKNADQKVKDYLKANNTDVVSYVRWEMGN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_ECOL6
Sequence: MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MINE_NAUPA
Sequence: MSFFDIFKKKKSKDVAKDRLMMMLAYERANTKIENLDEMKKDLINVVKKYLNVKDVHIKSNSNQDIETLEVEIILNK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: HBA_ALCAA
Sequence: MVLSATDKSNVKAAWGKVGGNAPAYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKAHGEKVANALTKAVGHLDDLPGTLSDLSDLHAHKLRVDPVNFKLLSHTLLVTLAAHLPSDFTPAVHASLDKFLANVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DOST_MYCTO
Sequence: MTHPDRANVNPGSPPLRETLSQLRLRELLLEVQDRIEQIVEGRDRLDGLIDAILAITSGLKLDATLRAIVHTAAELVDARYGALGVRGYDHRLVEFVYEGIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDISRHPASVGFPLHHPPMRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAAGIAVDNARLFEESRTREAWIEATRDIGTQMLAGADPAMVFRLIAEEALTLMAGAATLVAVPLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVSGTSIGGVFHDRTPRRFDRLDLAVDGPVEPGPALVLPLRAADTVAGVLVALRSADEQPFSDKQLDMMAAFADQAALAWRLATAQRQMREVEILTDRDRIARDLHDHVIQRLFAVGLTLQGAAPRARVPAVRESIYSSIDDLQEIIQEIRSAIFDLHAGPSRATGLRHRLDKVIDQLAIPALHTTVQYTGPLSVVDTVLANHAEAVLREAVSNAVRHANATSLAINVSVEDDVRVEVVDDGVGISGDITESGLRNLRQRADDAGGEFTVENMPTGGTLLRWSAPLR
What is the function of this protein?
Interacts with the two-component regulatory system DevR/DevS (DosR/DosS) involved in onset of the dormancy response.  Required for full induction of the DevR (DosR) regulon; required during early adaptation to anaerobiosis, to start induction of the DevR regulon (By similarity).  May act as a direct hypoxia/oxygen sensor (By similarity).  May be the secondary sensor for CO (By similarity).  Donates a phosphate group to DevR (DosR) (By similarity).
What are the official names of this protein?
Oxygen sensor histidine kinase response regulator DosT.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_ALKCK
Sequence: MKIIELKEGEAVSLKRSGLHGSEAEIATVNTIIETVKKEGDQALVDYTQQFDGVELTDLCVTKAELDNAYRHIDQPVLAAIRQAIANVRAFHEQQKAKSWFQTAPDGTILGQRVTPLDAVGVYVPGGKAAYPSSIIMNVVPAQVAGVKDISMVSPSGKNGTLPPAVLATAAELGVHTIYKLGGAQAVAALAYGTETVRPVDKITGPGNKYVALAKRAVFGDVAIDMIAGPSEICVLADEKANPAYVAADLLSQAEHDEDATAVLVTPSRKLAEAVQQETARQLATLPRKEIAGRALEQFGALYVTASLAQAIEVVNQLAPEHLEIATEEPLALLGRVKHAGAIFLGSYSAEPVGDYFAGPNHVLPTNGTARFASPLSVDDFVKKSSIISYSKTALAENGKAITELARLEGLEAHARAIDIRLEDM
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: Y2881_DICDI
Sequence: MSQKGLFGILGEVVKNTGLILHRTGCKMQGDYAYVEKLNRHTRLTAFGDNAPIVGQKSFIAPNASIIGDVVIGKESSIWYNAVLRGDVNSIHIGDKTVVSDRTVVHCSSNGPLGPKPTQIGDKVYIGPGSIVHAATILGESFIGTGSTLCDGSVVEKNGFLEAGSLLTAGKTIKSGEYWGGSPAKFIRQVTKDDESQLEKIIEQNINLSEQHEKQTSKSAKELNNDLLQKYVKNRTRSDHILNNPL
What are the official names of this protein?
Uncharacterized protein DDB_G0288155.
Protein: QCR9_SOLTU
Sequence: MESAARRSGGGVLEGFYRLVMRRTPVYVTFVIAGALLGERAVDYGVKTLWEKNNVGKRYEDISVLGQRPVDE
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 9, Complex III subunit 9, Complex III subunit X, Ubiquinol-cytochrome c reductase complex 8.0 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCR10/QCR9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ATPG_SHIF8
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HTF_LOCMI
Sequence: QVTFSRDWSP
What is the function of this protein?
The in vivo function of this peptide is unknown.  Has no adipokinetic or hypertrehalosaemic activity in locusts.  Has hypertrehalosaemic activity in the cockcroach P. americana.
What are the official names of this protein?
Hypertrehalosaemic hormone, Lom-HrTH, Hypertrehalosaemic neuropeptide, Peptide hormone.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1299_PSEAE
Sequence: MAAKVEPFWKRKTLAQLDQDEWESLCDGCGLCCLQKLEDEDDGSVYYTRIACKLLDLQSCRCTNYAERIRFVPDCIQLTPAQADEFQWLPPTCGYRLVAEGKDLPLWHHLVCGDPERVHKERISQSGRMLSETQVAEDDWEDYLIFRAG
What are the official names of this protein?
UPF0260 protein PA1299.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: YEY8_SCHPO
Sequence: MNRLQAKKAVNVSRHEQKRIRYKLTPEEVKAERKERKRRAAIQRAEKKLIRAKGEALVAFQAVSNPSCNFLVIDFEAYEFNQKIITEAGITMRINGEWDYHHYRIKNFLHLRNGRFVPDEADNFQFGDSKIVTKIAFISILKKILKTPNLHLVGHGVENEIKYANVLGIPIPKDVTVLDTQNVFSFFQSLFLKEISNSNNISLAKMLTHLNIRAFCLHNAGNDARYTSEALREMTNKFTLSNF
What are the official names of this protein?
Uncharacterized nucleolar protein C2C4.08.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GRPE_VIBCH
Sequence: MSNEEIKNKDEQLQQDAVETEAEVVGTDADIDWNQAADEIDEKEAKIAQLEAALLVSEERVKEQQDSVLRARAEVENMRRRSEQEVDKARKFALSRFAEELLPVIDNLERAIQAADGEVEAIKPLLEGVELTHKTFVDTIAKFGLKEINPHGEVFNPEFHQAMSIQESAEHEPNTVMFVMQKGYELNGRVLRPAMVMVSK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDH_SINHE
Sequence: MGSTSTPASSTNRLQDKVAIITGGAGGIGETTAKLFVRYGAKVVIADISDDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGQHGIRVNCVSPYVVASPLLTDVFGVDSSRVEELAHQAANLKGILLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYTRTNPAFPTALKHGLA
What is the function of this protein?
Oxidoreductase involved in lignan biosynthesis (PubMed:26359402).  Also involved in the biosynthesis of etoposide, a chemotherapeutic compound of the topoisomerase inhibitor family (PubMed:26359402).  Catalyzes the stereospecific conversion of (-)-secoisolariciresinol to (-)-matairesinol via a lactol intermediate (PubMed:26359402).
What are the official names of this protein?
Secoisolariciresinol dehydrogenase, PhSDH.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PEX3_MOUSE
Sequence: MLRSMWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKIREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQQLNSESLTALLKSRPSNKLEIWEDLKIISFTRSIVAVYSTCMLVVLLRVQLNIIGGYIYLDNATVGKNGTTVLAPPDVQQQYLSSIQHLLGDGLTELVTVIKQAVQRILGSVSLKHSLSLLDLEQKLKEIRILVEQHQSSWNDKDVSRSSLCQYMMPDEETPLAAQAYGLSHRDITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHGNSINSLSSVSLPLAKIIPIVNGQIHSVCSETPSHFVQDLLMMEQVKDFAANVYEAFSTPQQLEK
What is the function of this protein?
Involved in peroxisome biosynthesis and integrity.  Assembles membrane vesicles before the matrix proteins are translocated.  As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
What are the official names of this protein?
Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal assembly protein PEX3.
What is the protein family that this protein belongs to?
Belongs to the peroxin-3 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: KA134_TITST
Sequence: GCRQCGGGCNKHGKCINGKCKCY
What is the function of this protein?
Blocks the potassium channel Shaker B.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 13.4, Toxin Tst-17.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 13 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21B_AGRFC
Sequence: MQVLVRDNNVEQALRVLKKRMQREGIFREMRARESYEKPSEKRVREQAEAVRRHRKLEKKKMQREGLLPAPKKAVRTR
What are the official names of this protein?
30S ribosomal protein S21 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: GPR_BACAN
Sequence: MKEPLDLSKYSVRTDLAVEAHQMLQERQEEQQQGIQGVIVKEREEEGIIITKVTIDEVASESMGKKPGNYLTLEVQGIRQQDTELQQKVERIFAKEFSYFLEEVGVTKEASCLIVGLGNWNVTPDALGPIVVENVLVTRHLFQLQPESVEEGFRPVSAIRPGVMGITGIETSDVIYGIIEKTKPDFVIAIDALAARSIERVNSTIQISDTGIHPGSGVGNKRKELSKETLGIPVIAIGVPTVVDAVSITSDTIDFILKHFGREMKEGNKPSRSLLPAGFTFGEKKKLTEEDMPDEKSRNMFLGAVGTLEDEEKRKLIYEVLSPLGHNLMVTPKEVDAFIEDMANVIASGLNAALHHQIDQDNTGAYTH
What is the function of this protein?
Initiates the rapid degradation of small, acid-soluble proteins during spore germination.
What are the official names of this protein?
Germination protease, GPR endopeptidase, Germination proteinase, Spore protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase A25 family.
Protein: PANB_SHIB3
Sequence: MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFADEGLNVMLVGDSLGMTVQGHDSTLPVTVADIAYHTASVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_STRPC
Sequence: MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKKYKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RS13_PSEP1
Sequence: MARIAGVNIPDNKHTVISLTYIYGVGRTTAQKICADAGVNPAAKIKDLSDEQIETLRGEVAKFTTEGDLRRDINMKIKRLMDLGCYRGLRHRKGLPVRGQRTKTNARTRKGPRKPIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.