PharMolix/UniProtQA huggingface dataset:
Protein: IRS1_HUMAN
Sequence: MASPPESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGHHDGAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSSSSSEDVKRHSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQCPQECTPEPQPPPPPPPHQPLGSGESSSTRRSSEDLSAYASISFQKQPEDRQ
What is the function of this protein?
May mediate the control of various cellular processes by insulin.  When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.  Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
What are the official names of this protein?
Insulin receptor substrate 1, IRS-1.
Protein: MSHC_KINRD
Sequence: MRSWSVPEVPALPGRGPRVHLHDTATGGLVPVGPEAGTATLYVCGITPYDATHLGHANTYVAFDLLGRAWRDAGLDVRYVQNVTDVDDPLLERAEATGVDWRDLAESQVELFRGDMEALSVVPPQRYLGVVEAVDLVAEAVRDLLAAGAAYRVPGTDGGPDGDVYFPVDADAAFGTVGGYDLETMLALSAERGGDPQRPGKRNPLDPLLWRVERPGEPAWEAGELGRGRPGWHIECTAIALEHLGMPIDVQAGGSDLVFPHHEMGAAHAHLLRPRARPFARAYAHSGMVALDGEKMSKSKGNLVLVSRLVAAGVPAAVVRLAIVDHHWRTDWEWTDEVLAQARARHERWSAAVAAPAGPPAEALLATVRERLADDLDAPGAVAAVDAWVEQARTTAGTDAQAPDLVRRTVSALLGVVLP
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: FQR61_MYCTO
Sequence: MDISRWLERHVGVQLLRLHDAIYRGTNGRIGHRIPGAPPSLLLHTTGAKTSQPRTTSLTYARDGDAYLIVASKGGDPRSPGWYHNLKANPDVEINVGPKRFGVTAKPVQPHDPDYARLWQIVNENNANRYTNYQSRTSRPIPVVVLTRR
What is the function of this protein?
Involved in a F420-dependent anti-oxidant mechanism that protects M. tuberculosis against oxidative stress and bactericidal agents.  Catalyzes the F420H(2)-dependent two-electron reduction of quinones to dihydroquinones, thereby preventing the formation of cytotoxic semiquinones obtained by the one-electron reduction pathway.  In vitro, catalyzes the reduction of menadione to menadiol; since menaquinone is the sole quinone electron carrier in the respiratory chain in M. tuberculosis, the physiological electron acceptor for Fqr-mediated F420H(2) oxidation is therefore likely to be the endogenous menaquinone found in the membrane fraction of M. tuberculosis.
What are the official names of this protein?
F420H(2)-dependent quinone reductase MT1299, Fqr.
What is the protein family that this protein belongs to?
Belongs to the F420H(2)-dependent quinone reductase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DRS71_PHYTB
Sequence: ALWKDVLKKIGTVALHAGKAALGAVADTISQ
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Dermaseptin-7.1TR.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NEU1_TACAC
Sequence: CYIQNCPLG
What is the function of this protein?
Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.  Acts by binding to oxytocin receptor (OXTR) (By similarity).
What are the official names of this protein?
Oxytocin, Ocytocin.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_SHEPC
Sequence: MATVNQLVRKPRAPKVDKTNVPALNACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCAGVSSRRQGRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: Y009_DICNV
Sequence: MSSVAITICILSLVASLGLWLGNIKIRGVGLSIGGVLFGGIIISHIMNLPTVASFMQQKNIVLDSQTLYFVQEFGLILFVYTIGIQVGPGFFASLRSSGLKLNAFAALIVLLGGLCSVILYYLFSIPLPAILGILSGAVTNTPSLGAGKQIIAELGGEQMTELMGMGYAIAYPFGIIGVLLAMWLIRLIFKIRPERELQFFDKEQQRQKGLAGINIRITNPNINNILLREIPDYDLNTVIYSRLKRNDELIIPHPNTTLYLNDILHLVGNKKSLNKMQIILGEEAGHEPLNSGDSPIKNERAVVTNEQVCGKKLAQLQIQSQYDVVISRINRAGVELIPSDEMALQFGDVLHLVGRQKNIATVLSLIGNAQQKLQQVQMLPVFIGIGLGVLLGSIPIYLPGFPVALKLGLAGGPLVVALVLARIGSIGKLYWFMPPSANLALREIGIVLFLSVIGIHAGEHFFSTLLSKDGFSWICYGAIITLLPLLIAGIIARYYSKMNYLTICGLLAGAMTDTPALAFANAIQENNGASVLAYATVYPLTTFLRIMLPQLIAVLLWAAH
What are the official names of this protein?
Putative transport protein DNO_0009.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL22_SYNP2
Sequence: MTIDTQTEVKAIARYIRMSPIKVRRVLDQIRGRSYREALIILEFMPYRACEPVLKVLRSAVANAEHNEGLDPADLVVSAAFADAGPVLKRFRPRAQGRAYQIRKPTCHITVAVAPGSAE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: 1108L_ASFK5
Sequence: MKVLILVLLGVVILQAAPIRKLEDLLPTRNPPQNELVYWCTYANQCDFCWECIHGICRNRIQADWPVIHQNDWIINCTVSRWNGICRYYEGPRGHIDHEMDCANPTYHTYPHIEYMKIYVRDDL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-8L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
Protein: TRUB_STRGG
Sequence: MTEQTTTPDGLVIVDKPSGFTSHDVVAKMRGIARTRRVGHAGTLDPMATGVLVLGVQRATKLLGHLALTEKEYLGTIRLGQDTVTDDAEGEITSSTDASGVTRASIDAGVAALTGRIMQVPSKVSAIKIDGKRSYARVRGGEEFEIPARPVTISSFRVYDVREAVAEDGTPVLDLVVSVVCSSGTYIRAIARDLGAGLGVGGHLTALRRTRVGPYGLDAARTLDQHQEELTVMPVAEAAASAFPRWDVDEKRAKLLLNGVRLDMPAHPPGPVAVFGPDGAFLVLVEEEKGKAKSLAVFA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: CNTA_ECO57
Sequence: MSNLSPDFVLPENFCANPQEAWTIPARFYTDQNAFEHEKENVFAKSWICVAHSSELANANDYVTREIIGESIVLVRGRDKVLRAFYNVCPHRGHQLLSGEGKAKNVITCPYHAWAFKLDGNLAHARNCENVANFDSDKAQLVPVRLEEYAGFVFINMDPNATSVEDQLPGLGAKVLEACPEVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPGFSDSVQVDRYWHTMHGNWTLQYGFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPIKGMMTVIYEFPVDSETTLQNYDIYFTNEELTDEQKSLIEWYRDVFRPEDLRLVESVQKGLKSRGYRGQGRIMADSSGSGISEHGIAHFHNLLAQVFKD
What is the function of this protein?
Converts carnitine to trimethylamine and malic semialdehyde.
What are the official names of this protein?
Carnitine monooxygenase oxygenase subunit, Carnitine monooxygenase alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. CntA subfamily.
Protein: CP4F3_RAT
Sequence: MPLLSLSWLGLGHTAASPWLLLLLVGASCLLAYILPQVYAVFENSRRLRRFPQPPPRNWLFGHLGLIQSSEEGLLYIQSLSRTFRDVCCWWVGPWHPVIRIFHPAFIKPVILAPASVAPKDRVFYRFLRPWLGDGLLLSTGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQRLASQGSARLDMFEHISLMTLDSLQKCVFSFDSNCQEKPSEYITAILELSALVARRHQSLLLHVDLFYHLTRDGMRFRKACRLVHDFTDAVIRERRCTLPDQGGDDALKAKAKAKTLDFIDVLLLSKDEHGEALSDEDIRAEADTFMFGGHDTTASGLSWILYNLAKHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPATAISRCCTQDIMLPDGRVIPKGVICRISIFGTHHNPAVWPDPEVYNPFRFDADNGKGRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRVLPDDKEPRRKPELILRAEGGLWLRVEPLSAGAH
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of the pro-inflammatory lipid mediator leukotriene B4 (LTB4).  Hydroxylates at the omega-1 and omega-2 positions LTB4.  This oxidation step leads to LTB4 inactivation, which is postulated to be a crucial part of the resolution of inflammation.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Cytochrome P450 4F3, CYPIVF3, Leukotriene-B(4) omega-1/omega-2 hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: GATB_STRPB
Sequence: MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSFPGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYNGWIKIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNSFSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPDLPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKVLSDYFETAVSLGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVFVHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFTGFLMKATKGQANPQVAQQLLAQELQKLRD
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: DCUP_MYCS2
Sequence: MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMTHFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWPVVEKAVRRVVEDGRAAVAAGAAGHIFNLGHGVLPATDPGIITDAVELVHSL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_RICCN
Sequence: MTNTKYYPEVSSNADFAGLEREILKFWQDNNIFQKSIDDRNGESEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTIKGKKVERRFGWDCHGLPAEMQSEKELGISGRLAIANFGIEKFNAHCRASVMKYANDWEEYVTRQARWVDFKNSYKTMDKNFMESVLWAFKELYNKGLLYESMRVMPYSWACETPLSNFETRLDNSYRERADKAVTVSFVLSHPVTTTTGSFKEYRILAWTTTPWTLPSNLALAVGSDIDYALVPKNDVCYIIAAYSVSKYAKELGLSGEENFEIIKGSALQGLNYKSLFDYFENHPNSFKIFAGDFVVEGDGTGVVHMAPGFGEDDQILCESKGIELVCPVDNSGKFTKEIPDLEGLQVFDANDKIIIKLKEQGNWLKTEQYIHNYPHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPFHVKDNLFGKWLENARDWSISRNRFWGTPLPVWKSDDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDELTRPNPDDPTGKSTMRRIEDVFDCWFESGSMPYGQAHYPFENKEWFEDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGVILDSTGQKLSKRLNNYADPLELFDKYGSDALRVTMLSSNVVKGQELLIDKDGKMVFDTLRLFIKPIWNAYHFFTMYANADSLKGKLNFSSKNVLDVYILSKLKIAVQKIEESLDNFDTQTAYHAVSAFFEVLNNWYIRRSRARFWKSAKDTDKQNAYNTLYSCLDTMAIAMSALVPMISEAIYKGLRHCEERNDTALSGKSNIIARKDTSLDKAISGVSHKIATALSVPRNDAISVHLCNYPTLSDFEINHELVATMDNVLDICSNSLFIRSTENIRVRQPLASIAIISKHNNNLKDFEDLIKDEINVKAVIYRDDLENYASKKLSINFPMLGKRLPHKMKEIIAASKKGEWEAITGGLAICGETLNSDEYKLVLEPYSHIKGAASFENNSSLLILDLELTPELIEEGYARDIVRFIQQARKDADFSITDRILIEIISEFNLSKIIDNYGDFIKEQTLGEFAKNFTPDYVSKVALENHQIQLKVKKS
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KARG_CALSI
Sequence: MADAATIAKLEEGFKKLEAATDCKSLLKKYLTKSVFDQLKDKKTSLGATLLDVIQSGVENLDSGVGVYAPDAEAYTLFAPLFDPIIEDYHKGFKQTDKHPNKDFGDVNQFVNVDPDGKFVISTRVRCGRSMEGYPFNPCLTEAQYKEMESKVSSTLSNLEGELKGTYFPLTGMTKEVQQKLIDDHFLFKEGDRFLQAANACRYWPTGRGIYHNDNKTFLVWCNEEDHLRIISMQMGGDLGQVYRRLVSAVNEIEKRVPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGKYSLQVRGTRGEHTEAEGGVYDISNKRRMGLTEYQAVKEMQDGILELIKIEKEMQ
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: LEUD_SHESH
Sequence: MNPFTSHTGLAVMIDSANVDTDQIIPKQFLSKVTRDGFGVHLFHDWRYLDEAGDEPNPGFSLNLPRYKGASILISKENFGCGSSREHAPWALADFGLRAIIAPSFADIFYGNSINNGLLPVRLTDVEVQQLMDEVEASEGAEITVDLEELTVTSPSGAVFNFEIAGSARHNLLNGLDAIGLSLACADQIARYEAQLPTWKA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: UBIE_YERPY
Sequence: MVDQEKETTHFGFRTVAKEQKEGMVAEVFHSVAAKYDLMNDLMSFGVHRIWKRFTVDCSGVRRGQRVLDLAGGTGDLTAKFSRLVGEQGEVILADINESMLRMGREKLRDKGIVGNVSYVQANAEALPFPDNYFDCITISFGLRNVTEKEKALRSMFRVLKPGGRLLVLEFSKPLLEPLSKAYDAYSFHILPKIGELVAQDAESYRYLAESIRMHPDQETLKGMMADAGFENVTYSNLTGGIVALHRGFKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: CH10_PARL1
Sequence: MKFRPLHDRVVVRRVEEESKTAGGIIIPDSAQEKPSQGEVVAVGPGARGDDGKLVALDVKVGDRVIFGKWSGTEVKIDGEELLIMKESDIMGVLEGAASKKKAAA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_MACCJ
Sequence: MLIVYYSLTGNVKRFIQKTKYTNTLTLDQAEGINEPYIIVTGTIGFGEIPDPVRQFLDRHSANLLAVAASGNRNWGQNYARAGDLISSTYHVPLLMKFELHGNDNDVKEFNIKVEEISEYHTRETVQSY
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: SECA_ECOL6
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: KCY_PYRCJ
Sequence: MVVVAISGQPGSGKTTVAREVARVLKLPMVSSGSIFRELAAKYGMDLLEFHKYAEQNTEIDKIVDSIALEKAKAGNVVLEGHLTAWIVRPYADVCIYLKASKEVRARRVAMRDGVSFDAALREIEERERLNKKRYLAIYEIDIDNLSIFDLVLDTSYLSINDTVRISLDFICTSLNSKYMKNFC
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EI3E2_DROWI
Sequence: MAQFDLTRINCQYLDRHLTFPLLEFLCGKEIYNQQELLEYILETVNKTNMIDYTMDTRKRLNLSQEMPEELVQRKAEVLATLKQLQNEVAPIMKATDILKNGESMKDSKTFVNALQKDYNFKMEHLYSAYKLAKYLYECGNYQESTSYLYFCLIVMAPNDKNYLNVLWGKLAAEILTLNWNTALEDLTRLRDYIDSANFSTIQALQQRTWLIHWSVLVFFNHPKGRDLIIEMFLYKPLYLNAIQTMCPHIMRYLATAVVINRTRRNALKDLIKVIQQESYTYRDPITEFLECLYVNFDFEGARLKLHECQTVILNDFFIVACLNEFVEDARLMIFETFCRIHQCITISMLADKLNMKPNEAECWIVNLIRNARLNAKIDSKLGHVVMGTQPLSPYQQLVEKIDSLSMRSEHLAGLIERKSKQKNQESIDSWKYY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E-2, eIF3e-2, Eukaryotic translation initiation factor 3 subunit 6-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NARF_ANOGA
Sequence: MSRFSSALQLTDLDDFITPSQECIKPVKIETSKSKTGAKITIQEDGSYVQESSSGIQKLEKVEITLADCLACSGCITSAEGVLISQQSQEELLRVMNANNLAKLNNQRDEIKFVVFTVSQQPILSLARKYNLTPEDTFEHIAGYFKKLGADMVVDTKIADDLALIECRNEFIERYNTNRKLLPMLASSCPGWVCYAEKTHGNFILPYIATTRSPQQIMGVLVKQYLAKQLQTTGDRIYHVTVMPCYDKKLEASREDFFSEVENSRDVDCVITSIEIEQMLNSLDLPSLQLVERCAIDWPWPTVRPSAFVWGHESSGSGGYAEYIFKYAARKLFNVQLDTVAFKPLRNNDMREAVLEQNGQVLMRFAIANGFRNIQNMVQKLKRGKSTYDYVEIMACPSGCLNGGAQIRPEEGRAARELTAELECMYRSLPQSTPENDCVQTMYATFFDSEGDLNKRQSLLHTSYHQIEKINSALNIKW
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins (By similarity).
What are the official names of this protein?
Probable cytosolic Fe-S cluster assembly factor AGAP009023.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: G6PI_LACLA
Sequence: MAHIKFDYSKLTPFVAENELDEIQWQIDGAAKLLHEGKGAGSDYIGWLDLPEDYDKEEFARIQKAAKKIQSDSEVLIVIGIGGSYLGARAAIDFLSNSFVNLQTAEERKAPRILYAGNSISSSYLADLVDYVADKDFSVNVISKSGTTTEPAIAFRVFEEMLVKKYGREEANKRIYATTDKEKGAVKVNADANNWETFVVPDSVGGRFSVLTAVGLLPIAASGADITALMEGANAARKEYTSTNVHENDAYAYAALRNILYRKGKFSEILINYEPSLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQWIQEGTRTVFETAIRIEKPRKNINIPELDADLDGLGYLQGKDVDFVNKKAADGVLLAHTDGNVPNMIVTLPEQDEFTLGYAIYFFELAIGVSGYLNGINPFNQPGVEAYKKNMFALLGKPGFEELSKELNDRL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNC_MESFL
Sequence: MIEFKKVEKVWPNGKHVLKDINLKINAGEFVAVIGLSGAGKTTLLKTINKINNISSGEIFIDINENEKYEINKTKGKSLRNLRKHIGLMSQEYNNIEKQTVLKNVLNSRVAQMNFFRAMAGFFTKEEKQNALAALEKLNLLEFSYIRADNLSGGQQQRVALARTINQNPKIIIADEPVSALDPILANRVMEDFKKINSELNITVIINIHHVDLALKYCDRIIGLKDGEIVFDGDPKKLNESKLEEIYGK
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.