PharMolix/UniProtQA huggingface dataset:
Protein: MUTL_RHIL3
Sequence: MAIRQLSETLINQIAAGEVIERPASAAKELIENALDAGATRIEIATSGGGKALLRVSDNGSGMDAADLELAVRRHCTSKISETLEDIRTLGFRGEALPSIGSVARLSIASRRRDSAGGHEIAVAGGKIAHLRPAAANPGTIVEVRDLFFATPARLKFLKTEKAEAGAITEIVKRMAIAFPAVRFVLSGSDRTTLEFPATGDDHLGRMAQVLGKEFRDNAIALDAVREEIALTGFAGVPTFNRGNSAHQYAFVNGRPVQDKLILSAIRGAYAETIPSGRYPVAVLSITLDPALVDVNVHPAKSDVRFRDPGLVRGLIVGAIREALARDGSRAATTGASDMLRSFRPGFPPNSQRPQTAWSAETSSSRPYQPATGFGERPQASFDGLSMPTARAEPQFSPQPAAAEPNARYPLGAARAQIHANYIVAQTEDGLVIVDQHAAHERLVFEAMRKALHSKRLASQVLLIPEIVDIPEEDCDRLMQHAAELSELGLAIERFGPGAIAVRETPAMLGEVDAHGLIRQLADEIAEWDTASGLSAKLEYVAATMACHGSVRSGRRLRPEEMNALLREMEVTPGSGQCNHGRPTYIELKLSDIERLFGRS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MDH_STAS1
Sequence: MTKKKISIIGAGNTGATLAFIVAQHELADVVLIDRPDNEGQVKGKALDIFESSPVYGFDAKVTGSVNYADTADSDIVVITAGSPRKPGMSRDDLVQINEKVMFDVTKEIVKYSPDCKIIVLTNPVDAMTYSVLKASGFPKERVIGQSGVLDTARYQSFIAEALNVSIKDIRGLVLGGHGDTMVPLVNSTNVNGVPLHQLLNQTQIEQIVERTRKGGAEIVALLGNGSAYYAPASAVFEMIEAILKDQHRLLPSIALLEGEYGFSDICLGVPTVLSEKGIENIVELALSDNEQAQLRISADSVEEVKQALKNQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: GUC1A_MOUSE
Sequence: MGNIMEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTGIVRRLQNGEHEEAGTGDLAAEAAG
What is the function of this protein?
Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated (By similarity).  This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure (By similarity).  May be involved in cone photoreceptor light response and recovery of response in bright light (PubMed:25673692).
What are the official names of this protein?
Guanylyl cyclase-activating protein 1, GCAP 1, Guanylate cyclase activator 1A.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Note=Subcellular location is not affected by light or dark conditions.
Protein: RBS_LACSA
Sequence: MASISSSAIATVNRTTSTQASLAAPFTGLKSNVAFPVTKKANNDFSSLPSNGGRVQCMKVWPPIGLKKYETLSYLPPLSDEALSKEIDYLIRNKWIPCLEFELEHGFVYREHHHSPGYYDGRYWTMWKLPMFGCTDSAQVMKEVGECKKEYPNAFIRVIGFDNIRQVQCISFIVAKPPGVL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PALI_DEBHA
Sequence: MHKGLLILDLFVSICLTIQLLPIISVPITGKGIGYNLHLSKYGNYTFGVLGLCTSNNICSKPKVGYPPETDAFYSFMDDENGEYPDFAAAELPSRARYVISKLLVVHIVGFCFTTLLFLLSLALTVILWLEESETKVPFKDAVRKKVKIRQNSRNNSSTELTESTSATKMNSLSDEGTVDNERKSKDITPYLNFMLMLSLLSFLSTLLAFLSDILLFIPHLSYLGWLQLCPIILLSTVTSMLCFIKRSISSRKYLNDEYRYENDDMRKSVNVGVLNWKDTDSDDGFYVYTNGFYSNYNNDDTPQEGHSHAPELFPANISTHSGWIRHSGHNETGDDVSISSSRDDSYNEHENIQMRLLNDHEHIT
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palI/RIM9.
What is the protein family that this protein belongs to?
Belongs to the palI/RIM9 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRTG_RAT
Sequence: MAPPVRPGMLPLLLLLLLPPLGSVPGVWSFSELFFMKEPQDATVTRKDPVFLDCQAHGEGPIKVTWLKNGAKLSENKRIQVLSNGSLYISEAEGRRGEQSDEGFYQCLAVNKYGAILSQKAHLTLSTISAFEVHPVSTEVPEGGVARFSCKISSTPPAVITWEFNRTALPMTMDSRVTALPSGVLQIYDAGPEDAGKYRCVAATHAHKRKSMEASLTIVPANETRSFYMPTIIASPQNVTASLHQTVVLECMATGYPKPIISWSRLDHKSIDVFNTRVLGNGNLIISDVKLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRRIHSNGRIKMYNSKLVINQIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAPYNVHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNEEYQVVLGNDTTHYIIDDLEPDSNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTENSIQVVELPGTVHEYLLEGLEPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAPKSPELHLEPLNCTTISVRWLQDTEDPAAIRGYKLFYKEEGQQEHGPIFLDTGDLLYTLSGLDPRRKYHVRLLAYNNLEDGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTTAQVINYTIRCNPVGLQNASLVLYLQTSETHMLVQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHTTLPEAPTGPPVGVKVTLIEDDTALVSWKPPDGPETVVTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPFPNSVELAVLPKDASESNQRPKRLDSSDAKVYSGYYHLDQKSMTGIAVGVGIALTCILICVLILIYRSKARKSSASKTTQSGTQPLSRASASVAAGSDMGKNLERATENEESSVPMMPSCFIDAKGGTDLIINSYGPIIKNNPKKKWRFFQDTKKIKVEQTQRRITQTVCFYQPGTTVLISDEDSPSSPGQTTSFPRPFGPTTLDTEHSANSEGSHETGDSGRFSHESNDEIHLSSVISSTPPTSNSLTCGDSDGDAAPKKHGDPAQPLPAEQTSAPQPTPAGLRHAAESVPV
What is the function of this protein?
May play a role in anteroposterior axis elongation.
What are the official names of this protein?
Protogenin, Protein Shen-Dan.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. DCC family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: T23O_SORC5
Sequence: MRPVPGPSVFWGAGSRLPAPLVARAHRLLRTRRANPARGASRITKDMNYWDYIHVEELLALQGGFDDDEQKVGNDEALFIVVHQIYELWFKLILRELTSARELFRQNPVPDQKLASAARSFRRVVTIFEQAIEHFRVMETLTTRDYLDFRDRLIPASGFQSAQLREIELLLGLDDALRIPLGREGSYKEALKTADGAPSAATRRVEARLASGPSLKHFLDEWLSRTPIDGSSEPEGVVGFLRSYTRSMRQENERRVQMAIDKALTPPDVERLRARYEAESAAAEAFLLAEDDPAADAATREKRRAVRAAIVFIESYRELPRLAWPREVLDRILEMEQAMLIWRQRHARMVERVIGRRTGTGGSAGVDYLDQTALRYRVFGDLWTVRSLLLRKPSVPEIEHASDYGFRVEDSP
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: JANC_PENJA
Sequence: MAFPGAGPILGAIAVSSCLYFLFDYVPIPRWWDKNAYLIGQMHPDEITGLECPYAYLRQIYGKYHWAPFVHKISPTLQKDDYPKYVMVLEIMDAIHLCLMLVDDISDGSDYRKGKPAAHKIYGPTETANRAYYRVTQILAQTTKEFPNLAPWLMGDLRDILEGQDMSLVWRRDGIGGFPTAAKDRAAAYRKMASLKTGALFRLLGHLVLENDSMDEVFTVIAWYSQLQNDCKNVYSSEYAKLKGLVAEDLHNREMTYPIVLALDAPEGHWVTRALESPSPRNIRNALKVIRSKYVRDKCTAELAESGASVKEWLQLWGRTEKLDLKA
What is the function of this protein?
Prenyl transferase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes janthitremanes such as shearinine K or shearinine A (PubMed:26213965).  The geranylgeranyl diphosphate (GGPP) synthase janG catalyzes the first step in janthitremane biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:26213965).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase janC then forms 3-geranylgeranylindole (3-GGI) (PubMed:26213965).  Epoxidation by the FAD-dependent monooxygenase janM leads to a epoxidized-GGI that is substrate of the terpene cyclase janB for cyclization to yield paspaline (PubMed:26213965).  Paspaline is subsequently converted to 13-desoxypaspaline by the cytochrome P450 monooxygenase janP, via beta-PC-M6 in a series of alpha-face oxidations (Probable).  The cytochrome P450 monooxygenase janQ is proposed to carry out sequential beta-face oxidation steps at C-7 and C-13 of 13-desoxypaspaline to form paspalicine and paspalinine respectively (Probable).  The indole diterpene prenyltransferase janD may then convert paspalinine into shearinine K which is substrate of janO and/or additional enzymes for oxidation and cyclization to generate shearinine A (Probable).
What are the official names of this protein?
Prenyl transferase janC, Janthitremanes biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RH39_ARATH
Sequence: MVGASRTILSLSLSSSLFTFSKIPHVFPFLRLHKPRFHHAFRPLYSAAATTSSPTTETNVTDPDQLKHTILLERLRLRHLKESAKPPQQRPSSVVGVEEESSIRKKSKKLVENFQELGLSEEVMGALQELNIEVPTEIQCIGIPAVMERKSVVLGSHTGSGKTLAYLLPIVQLMREDEANLGKKTKPRRPRTVVLCPTRELSEQVYRVAKSISHHARFRSILVSGGSRIRPQEDSLNNAIDMVVGTPGRILQHIEEGNMVYGDIAYLVLDEADTMFDRGFGPEIRKFLAPLNQRALKTNDQGFQTVLVTATMTMAVQKLVDEEFQGIEHLRTSTLHKKIANARHDFIKLSGGEDKLEALLQVLEPSLAKGSKVMVFCNTLNSSRAVDHYLSENQISTVNYHGEVPAEQRVENLKKFKDEEGDCPTLVCTDLAARGLDLDVDHVVMFDFPKNSIDYLHRTGRTARMGAKGKVTSLVSRKDQMLAARIEEAMRNNESLESLTTDNVRRDAARTHITQEKGRSVKQIREVSKQRNSRDKPSSSSPPARSTGGKTPVRKSSSSSFSKPRKASSPPEKSSKPKRKILKTVGSRSIAARGKTGSDRRPGKKLSVVGFRGKSSSARAS
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 39.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: CCSA_LOBMA
Sequence: MIFSILEHILTHISFSVVSIVLTIYFLTFLVNLDEIIGFFDSSDKGIIITFFGITGLLFTRWIYSGHFPLSNLYESLIFLAWAFSIIHMVSYFNKKKKKNLNAITAPSAIFIQGFAASGLLNMPQSAILVPALQSQWLMMHVSMMILGYGALLCGSLLSIALLVITFRKVGPTFLKKNLKKKFLLNELFSFDVLYYINEKNSILLQQNINFSFSRNYYRYQLIEQLDFLSFRIISLGFIFLTIGILSGAVWANETWGSYWNWDPKETWAFITWTIFAIYLHIKTNRNVKGINSAIVAAIGFLLIWICYFGVNLLGIGLHSYGSFTSS
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MURC_METEP
Sequence: MKLPEKLGPIHFIGIGGIGMSGIAEVMANLGYTVQGSDANDNANVRRLAENGIRTFVGHRAENVENAALVVVSTAIRRDNPELIEARERRLPVVRRAEMLAELMRFKSCVAVAGTHGKTTTTSLVATLLDAGNLDPTVINGGIINAYGTNARMGAGDWMVVEADESDGTFLKLPADVAIVTNIDPEHLDHFGSFEAIKDAFRRFIDNIPFYGFAVMCIDHPIVQDLVGHIEDRRIITYGENPQADVRLIDIDLKGGQSRFRVMIRDRRPGFRMEIEDLVLPMPGRHNALNATAALAVAHELGVPSDAIRKALAGFGGVKRRFTRTGEWNGATIFDDYGHHPVEIQAVLRAARASTDGRVIAIVQPHRYTRLQSLFEDFCTCFNDADTVIVAPVYAAGEAPIEGIDRDSLIAGLKARGHRDAVALERPEDLARLVAGRAGSNDYVVCLGAGTITQWAYALPGELAALQG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_ANADF
Sequence: MVGKIAPVAVDAMGGDHAPGAIVQGAINAARKGLPILLVGPEARLRDELARHRAGHALPIEVHHAGEVVEMDDHPGQAMRRKRDNSIRVCFELVKSGRASAMVSAGNSGAVMAGAIFVLGRPEGVERPAIISVLPALKGSSILLDMGAVVDCKPIHLVQFALMGEVYARRVVGVARPKVAILANGEEESKGTDLTRAAAAALRHAPLQFVGYCEGRDLLTGEVDVIVTDGFTGNVALKTMEGTAKVVGEYLKRALRSTAVSAIGGMLSKAALDGMKKRLDWREVGGAPLVGVNGVGFISHGRSDAIAIENAIHRARDAARAHFVDEIARAVAPSEALLEGAAGRAARPPPPRRASSHDA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MATRX_RABVB
Sequence: MNFLRKIVKTCRDEDTQKPPLVSAPPDDDDLWLPPPEYIPLKEITGKKNMRNFCVNGEVKVCGPNGYSFRTLRHILRSFDEIYSGNQRMIGLVKVVVGLALSGAPVPEGMNWVYKLRRTLIFQWADSRGPLEGEELEYSQEITWDDDTEFVGLEIRVSARQCHIQGRIWCINMNSRACQFWSDMSLQTQRSEEDKDSSVLLE
What is the function of this protein?
Plays a major role in assembly, budding and uncoating of virion after membrane fusion.  Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form.  Inhibits viral transcription and stimulates replication.  Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons.
What are the official names of this protein?
Matrix protein, Phosphoprotein M2.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus matrix protein family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host endomembrane system; Peripheral membrane protein. Host cytoplasm.
Protein: LRK57_ARATH
Sequence: MSHKVLQIVLVLLLTLFSSTHNSNGNFLMEEAAAAGLNGYCLLTNTTKHSYGQAFNNTPVPIKNSSFSFNIIFGIVPEHKQQGSHGMAFVFSPTRGLPGASPDQYLGIFNETNNGKASNNVIAIELDIRKDEEFGDIDDNHVGININGLTSVASASAGYYDDEDGNFKKLSLISTKVMRLSIVYSHTDKQLNVTLLPAEISVPPQKSLLSLNRDLSPYFLEETYLGFTASTGSIGALYYVMQFSYEEGVIYPAWDLGVIPTLPPYPKKSYDRTRRILAVCLTLAVFTALVASGIGFVFYVRHKKVKEVLEEWEIQNGPHRFSYKELFNATKGFKEKQLLGKGGFGQVYKGMLPGSDAEIAVKRTSHDSRQGMSEFLAEISTIGRLRHPNLVRLLGYCKHKENLYLVYDFMPNGSLDRCLTRSNTNENQERLTWEQRFKIIKDVATALLHLHQEWVQVIVHRDIKPANVLLDHGMNARLGDFGLAKLYDQGFDPQTSRVAGTLGYIAPELLRTGRATTSTDVYAFGLVMLEVVCGRRLIERRAAENEAVLVDWILELWESGKLFDAAEESIRQEQNRGEIELVLKLGLLCAHHTELIRPNMSAVLQILNGVSHLPNNLLDVVRAERLRGIPETSMEVLLGLDLNSFGTMTLTNSFVSHGR
What is the function of this protein?
Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici and to the pathogenic bacteria Pseudomonas syringae.
What are the official names of this protein?
L-type lectin-domain containing receptor kinase V.7, Arabidopsis thaliana lectin-receptor kinase a3, AthlecRK-a3, LecRK-V.7.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: OTC_STRPS
Sequence: MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHYLAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITEDADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPAFHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLYIPKV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDB_DESHY
Sequence: MSMRFIVGRAGTGKSTLCRQEIHKESQEHPEGLPLILLVPEQATHQMEMSLAHDPQSGGILRAQVLSFRRLGWRVFSEVGGGGKAVIGEVGKRMLLRRLLLNHRSDLRVFARSATRPGMADLLAQAIAEFKIYRITPDQLRGIEDADELLLQKTHELAFLYEELNKSLGTAARDPDDELNLVAGKISQAPFLQGAKIWVDGFKGFTPQELYVIQAMLGTAAEITVSLPLDPELLKAGTPRFKPGEELFYEPRQTYQGLVDLAREAKASISHVFLTETHRFEKAGLKHLERFYNAYPTQTFPGGDDSTAPDPLGIALFPAANKRAEVEGVARELRRLAREEGRTWRDCSVVTRDLPGYQGIIEQVFNAHEIPYFLDHKRPVIHHPLLELLLSAIETVQKDWAYEPLFRCLKTDFFPCSKDRIDRLENYCLAYGIHGSAWKGNRSWSYYPDPNHKEETAGLNETRQIIYDLFSPFDQAIRPHPEAGGPSVTVAQITEAIYELLIRLKVPEHLQEWAEAAHSRGDLAEAQLQNQIWDAVIQVLDELVAGLGEEVMDLSDFAMILTSGLENLQLGLIPPGYDQVLVGSLDRSRNPETAVLFLLGANDGILPGKPSDEGVFDELERLRLESKGIMLAPKGKVQVYEEQYFIYTALTRAREQLYISYPLTDEEGRGLTVSPVIHRLKMIFPGLPEKYLSLDEEEPGALPHPYALLPAYALHLQKLRQGSSLSPLWQAIRLWFLSQTAAFPQVQLLEKGLRDQNEEGKLPQPLARQLYGKRLVTSVSRLELFARCPFAHFAQYGLKLKERSNYRLSPPDMGQFFHAVLHDYAIALRERGLDWGELSKEQSWQLVNETAEPIALQLQNKILLSNARYRYLTHKLKRTVHHAVRVLGEHARQGVFLPMELEVKFGPQEALPPLEVPLSGGNSLLLRGQIDRIDGAVLGHEIYLRIFDYKSREAHVSLNQIYHGLDLQLLAYLDAALQGAQILVSSSGLAEGSKGSEGSEGSEDSEDSTIHPAGFLYFPVLEPQLKSKTLLYPEQLEKDRIKAVKVKGYLLADRQVLLAMDRDLENSSLLGIKLTKSGEFKKGSPILTEEQFALLRKHLQHFLRCSGEALLEGDISITPYRQGKHTACQFCSYKPLCHFDPYLPENNYRNLPVIQDEEFWQRVQSQDSEQYPEQHPPTSVPGETSRRALQKDGGNSPRGQELIWLGEDEAGAGKEDDGHE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: CC182_HUMAN
Sequence: MEPLYQAGSILMTVNTLQGKKMIESGLQSGDFSLSQSWPSCLPPPADLEILQQKVAGVQRELEDFKKEALKSIHYLEDAFCEMNGALVQQEEQAARVRQRLREEEDRGIVRNKVLTFLLPREKQLREHCKRLEDLLLDRGRDALRATKKSQAD
What are the official names of this protein?
Coiled-coil domain-containing protein 182.
Protein: SYH_GRAFK
Sequence: MAQKPSIPKGTRDFSPEEVAKRNYIFNTIQTEFKGFGFQPIETPSFENSSTLMGKYGDEGDRLIFKILNSGDFLKKADKDALANSDSLKLTSSISEKALRYDLTVPFARYVVQHQNEIEFPFKRYQIQPVWRADRPQKGRFREFFQCDADVVGSNSLWQEVEFVQLYDAVFNKLGLEGVTIKINNRKVLSGFAEVIGEQDKLIDFTVALDKLDKIGEEGVKKEMREKGISEEALNKIQPIFNLNGNFAEKIEGLKTILEGSETGQKGIEELQFIQNAIEEMPLSVAKLDLDVTLARGLNYYTGAIFEVAAPENVKMGSIGGGGRYDDLTGIFGLKDMSGIGISFGLDRIYLVLEELGLFPATVTENTKVLFINFGEKEALYAMKAVKRLREENIIAELYPDSAKMGKQMKYADKRSIPYVVLAGEEEINDKKFTLKHMKSGEQSNLDFNGLSGALK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_BACC7
Sequence: MRLRHKPYAMDRINEYSHIVIGNPEERAGNWKEVFGNEQPIHIEVGTGRGRFMYDMAKANPHINYIGIEKFTSVVVDALDKLIEEELPNLKLINKDAEDLTVFFAKGEIDRVYLNFSDPWPKKRHTKRRLTYKTFLRNYEEVLVEGGEIHFKTDNQGLFEYSLMSMAEYGMLLTYLSLDLHNSDFEGNIMTEYEEKFSSKGHRIYRVEAKYRTEPMQ
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: SPIT2_HUMAN
Sequence: MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVKNTYVL
What is the function of this protein?
Inhibitor of HGF activator.  Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.
What are the official names of this protein?
Kunitz-type protease inhibitor 2, Hepatocyte growth factor activator inhibitor type 2, HAI-2, Placental bikunin.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PURL_BACC0
Sequence: MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAKRPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSKEAAYFAEFQQMKMETPKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIAVAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEGGLAVAISESAIGANGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLTANVDEMRKAWKGAIPCLLK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.