PharMolix/UniProtQA huggingface dataset:
Protein: PETN_NYMAL
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL1_PYRHO
Sequence: MSRMAFDRQKIVEAVKEAKARAKPRNFTQSVEVAVNLKDIDLKRPENRFKLEVVLPHGRGKDVKIAVIADGAVAEAARRLGLDVISSAELEEIAKSPRQARKLAKKYDFFIAEAPLMPKIGRYLGRYLGPRNKMPVVVPPTMTNIEPIVEKLKKTVRIQLKDNPVVHAPVGTEKMSDEQLAENIEAVLNAIIGKLERGENQIRSVYVKTTMGPAVRVEG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: Y712_STAEQ
Sequence: MNIIPRTSLIIYLKHMKHERQIRKYGHIVHSNRQRKYVVMYINEADADNIVHKLMQLKYVHDIQGSPYKYLKKTYEKEKHEIQ
What are the official names of this protein?
UPF0298 protein SERP0712.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTD_PSEAE
Sequence: MSPFAPFDAQTQVLLIDDDPHLRQALRQTLDLAGLKVATLDDARQLDTAQCKDWPGVVVSDIRMPGIDGMELLRQLHEQDADLPVILITGHGDVPLAVQAMRGGAYDFLEKPFPSDALLDSVRRALEVRRLVLENRTLRLALAERHELHGRLIGRSAGMQRLREQVGSLAAIQADVLVLGETGAGKEVVARALHDLSSRRDGPFVAINAGALAESVVESELFGHEAGAFTGAQKRRIGKFEYANGGTLFLDEIESMSLDVQVKLLRLLQERVVERLGSNQLIPLDIRIIAATKEDLRQAADQGRFRADLYYRLNVASLRIPPLRERGEDIPLLFRHFAEAGAMRHGLTPRELDAGQSARLLAYDWPGNVRELQNAAERFALGLGLSLDDGVLPDAADEPHNLSAKVEAFERSLIAAELERPHNSLRSVAEALGIPRKTLHDKLRKHGLPFNTPGENPPDDGE
What is the function of this protein?
Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.
What are the official names of this protein?
C4-dicarboxylate transport transcriptional regulatory protein DctD.
Protein: TRUA_CALS8
Sequence: MRNILLTIEYDGTNYFGWQKQPNKKTVQGVIEDAIKKITGEDVNLVGSGRTDRGVHALGQKANFKTESKIPTEKFPLALNSVLPNDISIKDAAEVSLDFSARYSAKQKTYKYLIYNHKFRPAILCNYVYHFPYELDLVSMQKSCEYFIGEYDFSSFCSSGSETNSKVRRIFDCYLTFENDCIAIYITANGFLYNMARIIAGTILDVGVGRFKPTDIPLIIESKDRTKAGKTLPPWGLYLVDVVY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ACUK_PARBA
Sequence: MTSSVRNGSPSPSPALPSTTTPAEQESRNAMTMANNPGDWDSSESRPQSLSNGKGIGNGMVANGHQKPSTSSTAASANNASAKDPLRPRRKKAKRACFACQRAHLTCGDERPCQRCIKRGLQDTCHDGVRKKAKYLHDAPNEALIPGIRGNLYNQAQAARNKVNSNSQQRNGTNSNSDNNSTNTNSNNKPSHQDVSTNFFSTPSANNYHNVYTQAKSRQSQHMPSRVMQDATMNPSAFQAQPPASPTFDLSSNPQNHTLSPSIAQNSGTTPSSSASQNPDPYGSTFFDPSHPALFNFDIASMNFGNRYGALEFGMLGHLATGAGDTPPSDTATRRGSIGRSSGTFTVQNFGEGSSNQSPFLFGGDPVLNDWNPAGQGPTNPRNIYNQNSVSGQMTDHPHAFAIESAPMNFASPTSTESPQMTTVTQFDDPSVNFSSRTTLMPPTNTQHQQQPQPPRISTPSLKNMQVGVKRRYRSPSSIYESVKEPYSYTSGFHSLTAFIQRRFSPQKTLQIAKALASIRPSFIATTKTLNQDDLIFMEKCFQRTLWEYEDFIDACGTPTIVCRRTGEIAAVGKEFSILTGWKKEVLLGKEPNLNVNTGGSSSSGVSSRGSSTYNSRNSATTTVMDNQSLPAGRTQPVFLAELLDDDSVIEFYEDFAKLAFGDSRGSVMTTCKLLKYKTKEDGVGLFRNSNGEVSAGGGDTDANDSAGAGVGDGTTTAVNGVSNGSSNNATNVNANGNVNVIPNDLSGASSMKSSPKQAWGKSRIAGEAGMNQLGFRDGKVECSYCWTVKRDVFDIPMLIVMNFLPCI
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis PAAG_01030.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAD50_PLAF7
Sequence: MTTLEKIGIQGIRSYNDEDVEILEFATPITIIYGNNGSGKSTIIECLKVSCTGDFPPNAEKGKSFLHDPLISNKMNIRGKIDVLLNNYNNKRIGISRSYNLFYSKDKNKKVKHTFRALDNNIIIKKEKGDDLIITNKCVDINNHIPKLMGVSKALLENVIFCHHDENLWPFSESIKIKKKFDELFGDDHFSKILEELLKCKKYLNDLLKRKEFDLIHIKENFEKKKNIYIEIEKNEKEIQSAQICIQLDVEEIEENTIILNNLIKKKNLLYKLIGNIDSYFLLYTKFKVDAEAYKDLKEVYEENYTELLYFQEVFNNDINKCEICIQKVKQDIQNLQHEKDTCMFNYNESNKYDDNYELSKKQLNEYIIKRDDIRNKLKDIFFYNDQIFFSNYKGNSSSDMIKHSSINEGHQKEKLKKKFKKHDSVYIKDHLLKEYENLLHMYDIHKEDIALYNHDVMLSYKNEEHIPSNARLMEELFLICQNKVQYKTSNKSDDNKRNNNNNHFDDDNKRNNNNNHFDDDNKRNNNNNHFDDDNKRNNNNNHFDDDNKRNNNNNHFDDDNKRNNNNNHFDDDNKNKCDDKKFIEIPNVSNILSNVPYLKKKHEKKINSIRYILKRHISHIKRNKYKKRNVIYKIKNYKKRLLKIEKNITLLDIYKNKLNKLKSNEIIYEQNLKKIEKLNQLKCLYDNLTTLDNEMDTYNIQKENNYYEEQIEKNMKQINDIQKLKIWIHTFCNIIRNYNIFYEFIQRCKKIHEHCVIFFDILFSLLDVIKTDFYKIVDMLKERDMDLYYYIERGMQKKINVERNVCVERNVCVERNVCVENNICVEKNICVEKNICGEKNICGEKKKITKLKSNIEIEESVEKIKDNKINECDVNVDTLNKTNSIHHVNNIKINSKSLVCMNEHLQRKRENEKLNDYTCKLKKQKTHLDISILKNRKYLDILLNIINIFIDKYENKINNIKTLIIPLNQKVLEISKKLNNMNNNINEYKNYLSNFIHMLKEKKYKDVKDFVNYVEAIDNQIKIKKKNLWMLNGKEDLMNEFKNHLKSDEQNNSDNNKKVGVEKKKKKNCLFCKNTISQNNKDIVQIEMYIEEQKRDMLKKIEESEKDINILKNKKEENIILLNYYYYHIKHIHTYTNDSNEMIVKLKEELLSAQDSIEKYNIKIKNIHRKFQLVQKFKETCVYLINIQKDILDVEKYIKDESIKIKGNFQEMKNKIKDNVENNKMSNNTNKCNDTKTCNNTKTCNNTYTCDHLFIEKLYHMIENLDISIEVKESNLLKNIKEFVKKFAKYNNKDIINIFYNKICTSNVNDSYSYIPYNDIINVDLYQQYNYQNNYKNRFKYNLYKINNANYICKLLSPHQKVSLKDCYSSDQTPQKIYVDEEKEKEKEKKKKKKKKTDNDGYYDEIFHCDNMEYDEQFYEDDDHHSYNKSKSLIENYITPCKNKEESVKEPNMCSIKHIYDNGSSNDDILNNDKTVLLNKINSSYLSFVLNIGTSYYSNEEIKENNKNDTNKMCDDTNKMCDDTNKMYDDTNKMYDDTNKMYDDTNKMYDDTNKMCDDTNKRYDDTNKMCHDTNKMCDDTNQMYDDTNKRYDDTNKRYDDTNKMCDDTNQMYDDTNKRYDNINQNTYGTFLKCSDFLHNLPSIILNNKHFEKMYRNFLSYLNVEEYTRKEQNKMIEKMKVVIKDRRAYVIKKSKVLEKTINIDKRIRDLIKKMDIYILYYKEKKKKIIDEKINVKNLLIEQRDTQLKYIKRCIRNNKKSIFLEKRNYYLKMNMIYILIKKLKHTEEEIVNKEKYLKDVKEKLNNNEIIKNQVICIDKKINEKKEHILCLEKEKINIEKMLHNIIMNTNMKKMYEQFLEHHQTFILSLNQLKASFFLYERKNIKNSNMCKLEYKDEINGDKKKENDNTVSSNNDSIINNDNRNKKNRYNDEENGINYINDIVKKLEENYNNNTNIYNFINKTFDITDCLKNRLKDIIKIEEDDLNEQIEKYTKSITALKIKEAEMNGKICLRKEYLEKLKEDIKSETLINIDKEYKKKIIEIFVYKNLIKDLQNFHFSFDQAIIKFHSLKMQEINLSIKNLWRRVYNSADIDYIYIKSDIQTEPTDKSSQRRSYNYRVVMVKDNCELDMKGRCSSGQKVLSSIIIRLALAESFSIKCGILALDEPTTNLDKANSRNLASLLANIVELRKSSSSFQLILITHDNYFVDILSQYGLTNCFYKIKKNNLGYSKIERVNT
What is the function of this protein?
Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis.  In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity (By similarity).
What are the official names of this protein?
Probable DNA repair protein RAD50.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: LGT_LISIN
Sequence: MGNGVQPLDPVAIQIGSISVKWYGVIIASAVVIALLLALSEANKRKMDKEIIVDLLIWAIPISIISARIYYVIFEWDFYKNNLGEIVKIWHGGIAIYGALIGAVLTAVIFSRIKKISFWKLADVVAPSLIIAQAIGRWGNFMNQEAHGAETTRAFLEGLHLPEFIINQMYIDGAYYQPTFLYESLWNVLGFIVLLIIRRTKIRSGELFLSYVIWYSFGRFFIEGMRTDSLMWGDFRVSQVLSLLLIVLSIGLIIYRRVKMNPPYYMEDKLGKVAKKK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4550_NOSS1
Sequence: MSNLLWKSLVVSPAVLGATLLVSSAAIAATNATTELSVTETVVPTELAQQPEIVAQAAPITEDTKVIDQVNRYSNEGKGNAQSQVTSVSQFSDVQPTDWAFQALQSLVERYGCIAGYPNGTYRGNRALTRYEFAAGLNACLDRVNELIATATADLVTKQDLATLQRLQEEFSAELATLRGRVDALEARTAELEANQFSTTTKLVGEAIFAVTDAFGENTGDANNTVFQNRVRLGLQTSFTGRDVLTTRLAAGNATGFDFRDNNNNSIGASGQGLQTFQVGSTGNNNVEIDRLTYEAPFGPAQVYLAASGGRHSHYAAVNNPYFFDKTDGGNGALSTFSSENPIYRIGGGAGIAFNVPFGQGGSILRPSSFTVGYLASDANNPGPNQGLFNGDYAALGQLNFSVGDRLALAATYVHGYHGASGSALFDSGANGAIVGTSLANNNSFLNASSSNSYGLSAAFRPSDKLSVSGFVSYSDVTGFGANDDREVWSYGIGVALPDFGKRGNVLGIFAGAQPYARGVQAGANEVPYQVEGFYKYRVSDNISITPGVIWVTNPGQNSNADDAIIGTLRTTFTF
What are the official names of this protein?
Uncharacterized protein alr4550.
What is the protein family that this protein belongs to?
Belongs to the OprB family.
Protein: RNH2_BORRA
Sequence: MICGIDEVGRGCIFGPVLSAAVIFKTKPNFLNELDDSKKLTKTKREYLSSLILENAYYAFADISNEIIDKINIHNASLLAMQIAYQKLNIECNLVLVDGKFIPKIQAKQIRAIIKGDSMIDEIKAASIIAKVQRDKLMVEYDKIYPLYGLKKNKGYPTKEHKDAIKKHGILSLHRKSFRLI
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CONA_CANRO
Sequence: ADTIVAVELDTYPNTDVGDPSYPHXXXXXXSVRXXTAKWNMQNGKVGTAHISYNSVGKRLSAVVSYPNGDSATVSYDVDLDNVLPEWVRVGLSASTGLYKETNTILSWSFTSKLKSNSTHETNALHFMFNQFTKDQKDLILQSDATTGTDGNLXXTRVSSNGPSQGSTVGRALFYAPVHIWESSATVAGFDATFXXLIKSPDSHPADGIAFFISNIDSSIPSGSTGRLLGLFPDAN
What is the function of this protein?
Glucose/D-mannose specific lectin.
What are the official names of this protein?
Concanavalin-Ma, Con Ma.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: Y2224_GLOC7
Sequence: MAQGKGFGFGLGKIKELQEAFQKAQQVQEGAKQLQDELEQMSIEGHSSDGSVTVVMSGNQEPRSVTIQPTALEKGAEELSTLVTEAMKDAYSKSTDTMRQKMEELTSGLNLPGL
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein PCC7424_2224.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SYGB_PECCP
Sequence: MTDKTFLVEIGTEELPPKALRNLAESFAANFTAELDAANLAHGEVSWFAAPRRLALKVARLSASQPDREVEKRGPAIAQAFDAEGKTTKAAEGWARGCGITVEQAERLTTDKGEWLLYRAHAKGEQAQALLAGMISTALSKLPIPKLMRWSDKETQFVRPVHTVTMLLGDELIPGQVLGIHSARTLRGHRFMGEAEFTIDSADQYPQILLERGKVVADYDARKAKIKADAEEAARKIGGNADLSDSLLEEVTSLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYDNSGNLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFNTDRKKRLEDHLPRLETVLFQQQLGTLRDKTDRIQALAGWVAGQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDELPSSAVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKRLPLDLQTLTEEAVRLYGAKLTNANVVDDVIEFMLGRFRAWYQEEGHSVDTIQAVLARRPTRPADFDARVKAVSHFRSLDAAAALAAANKRVSNILAKSTDTLNESVNAAVLKDAAEITLATHLVVLRDKLTPLFAEGRYQEALVELASLREPVDAFFDQVMVMAEDEQVRVNRLTLLSQLRELFLQVADISVLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPL3_POPTR
Sequence: MADIETKSSQNQPLKTQNIFIGAQIFLRIVVIAASFASTWLMLTNKQTIDIGGFVLDANYSYSPEFKFLSYANIVVGAFSFVSLLFLVLVGRRSSNPTYYFILFLHDLALMSLVLGGCAAATVIGSLGKYGNSHTGWMQICDHFGKFCKRATTSVAFSYFSLVCLLILTITSASKSRQIQV
What are the official names of this protein?
CASP-like protein 1F2, PtCASPL1F2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FGL2_HUMAN
Sequence: MKLANWYWLSSAVLATYGFLVVANNETEEIKDERAKDVCPVRLESRGKCEEAGECPYQVSLPPLTIQLPKQFSRIEEVFKEVQNLKEIVNSLKKSCQDCKLQADDNGDPGRNGLLLPSTGAPGEVGDNRVRELESEVNKLSSELKNAKEEINVLHGRLEKLNLVNMNNIENYVDSKVANLTFVVNSLDGKCSKCPSQEQIQSRPVQHLIYKDCSDYYAIGKRSSETYRVTPDPKNSSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLRREFWLGNDKIHLLTKSKEMILRIDLEDFNGVELYALYDQFYVANEFLKYRLHVGNYNGTAGDALRFNKHYNHDLKFFTTPDKDNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQKYRGVRNGIFWGTWPGVSEAHPGGYKSSFKEAKMMIRPKHFKP
What is the function of this protein?
May play a role in physiologic lymphocyte functions at mucosal sites.
What are the official names of this protein?
Fibroleukin, Fibrinogen-like protein 2, pT49.
What are the subcellular locations of this protein?
Secreted.
Protein: TIG_STAAE
Sequence: MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVVENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVNEIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNTTIDIPEAMINTELDRMVSEFAQRIQQQGLDLQTYFQISGQDETQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNTLGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: NFYC2_ARATH
Sequence: MEQSEEGQQQQQQGVMDYVPPHAYQSGPVNAASHMAFQQAHHFHHHHQQQQQQQLQMFWANQMQEIEHTTDFKNHTLPLARIKKIMKADEDVRMISAEAPVIFAKACEMFILELTLRAWIHTEENKRRTLQKNDIAAAISRTDVFDFLVDIIPRDELKEEGLGVTKGTIPSVVGSPPYYYLQQQGMMQHWPQEQHPDES
What is the function of this protein?
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
What are the official names of this protein?
Nuclear transcription factor Y subunit C-2, AtNF-YC-2, Transcriptional activator HAP5B.
What is the protein family that this protein belongs to?
Belongs to the NFYC/HAP5 subunit family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CRBN_MOUSE
Sequence: MAGEGDQQDAAHNMGNHLPLLPADSEDEDDEIEMEVEDQDSKEARKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPEVLMILIPGQTLPLQLSHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQEFGIEVVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQVFPSKPISWEDQYSCKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPENPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKASNLNLIGRPSTVHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPETEDEISPDKVILCL
What is the function of this protein?
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2 or ILF2.  Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the fibroblast growth factor FGF8 (By similarity).  Maintains presynaptic glutamate release and consequently, cognitive functions such as memory and learning, by negatively regulating large-conductance calcium-activated potassium (BK) channels in excitatory neurons (PubMed:29530986).  Likely to function by regulating the assembly and neuronal surface expression of BK channels via its interaction with KCNT1 (By similarity).  May also be involved in regulating anxiety-like behaviors via a BK channel-independent mechanism (PubMed:29530986).
What are the official names of this protein?
Protein cereblon, Protein PiL.
What is the protein family that this protein belongs to?
Belongs to the CRBN family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane; Peripheral membrane protein.
Protein: TCNA_TRYCR
Sequence: MVAIADARYETSSENSLIDTVAKYSVDDGETWETQIAIKNSRVSSVSRVVDPTVIVKGNKLYVLVGSYYSSRSYWSSHGDARDWDILLAVGEVTKSTAGGKITASIKWGSPVSLKKFFPAEMEGMHTNQFLGGAGVAIVASNGNLVYPVQVTNKRKQVFSKIFYSEDDGKTWKFGKGRSDFGCSEPVALEWEGKLIINTRVDWKRRLVYESSDMEKPWVEAVGTVSRVWGPSPKSNQPGSQTSFTAVTIEGMRVMLFTHPLNFKGRCVRDRLNLWLTDNQRIYNVGQVSIGDENSAYSSVLYKDDKLYCLHEINTDEVYSLVFARLVGELRIIKSVLRSWKNWTATCPAFAPLLIQPLRRQRVVVVPLSPRLVLLAFCRQRLPKRMGGSYRCVNASTANAERVRNGLKFAGVGGGALWPVSQQGQNQRYRFANHAFTLVASVTIHEAPRAASPLLGASLDSSGGKKLLGLSYDEKHQWQPIYGSTPVTPTGSWETGKRYHLVLTMANKIGSVYIDGELLEGSGQTVVPDGRTPDISHFYVGGYKRSDMPTISHVTVNNVLLYNRRQLNTEEIRTLFLSQDLIGTEAHMDSSSDSSAHSTPSTPADSSAHSTPSTPVDSSAHSTPSTPADSSAHGTPSTPVDSSAHGTPSTPADSSAHGTPSTPVDSSAHSTPSTPVDSSAHSTPSTPVDSSAHGAPSTPADSSAHGTPSTPVDSSAHGTPSTPADSSAHSTPSTPADSSAHSTPSTPADSSAHSTPSTPVDSSAHGTPSTPADSSAHSTPSTPADSSAHGTPSTPVDSSAHSTPSTPVDSSAHGTPSTPVDSSAHSTPSTPVDSSAHGTPSTPVDSSAHSTPSTPADSSAHSTPSTPADSSAHGTPSTPVDSSAHSTPSTPADSSAHSTPSTPVDSSAHSTPSTPADSSAHGTPSTPVDSSAHGTPSTPADSSAHSTPSTPADSSAHSTPSTPADSSAHSTPSTPVDSSAHSTPSTPADSSAHSTPSTPADSSAHSTPSTPADSSAHSTPSTPVDSSAHSTPSTPADSSAHGTPSTPADSSAHSTPSTPVDSSAHSTPSTPADSSAHGTPSTPADSSAHSTPSTPADSSAHGTPSTPADSSAHSTPSTPAGSSANGTVLILPDGAALSTFSGGGLLLCACALLLHVFFMAVF
What is the function of this protein?
Developmentally regulated neuraminidase implicated in parasite invasion of cells.
What are the official names of this protein?
Sialidase, Major surface antigen, Neuraminidase, NA.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: Y3529_BORPE
Sequence: MLIQIADLFTPAEAAQIRARLEAADWVDGKVTAGYQSAQVKHNRQLSEQHPLAQELGGLILQRLAANNLFMSAALPRKIFPPLFNRYEGGEAFGYHVDNALRPVPGTAERVRTDLSATLFFSEPDSYDGGELVVDDTYGPRTVKLPAGHMVLYPGTSLHKVTPVTRGARISAFFWLQSLVREDSQRSLLLEMDVAIQRLNQDTPGHASIVQLTGVYHNLLRRWTDV
What are the official names of this protein?
PKHD-type hydroxylase BP3529.
Protein: CALM_MEDSA
Sequence: MADQLTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMMAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: NDHI_FLARA
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ATPF_SERP5
Sequence: MNLNATILGQAIAFVLFVWFCMKYVWPPIMAAIEKRQGEIADGLASAERAKKDLDLAQANATDQLKTAKAEAQVIIEQANKRKAQIMDEAKAEAEQERNKIVAQAQAEIEAERKRAREELRKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SYS_MYCVP
Sequence: MIDLKVLRENPDAVRASQLARGEDPGLVDALADADTARRAAISAADNLRAEQKSASRLVGKASPEERPALLAAAKELADKVRAAESAQAEAEKAYSAAHMAISNVIIDGVPAGGEDDFVVLDTVGEPTALTDPKDHLELGESLGLIDMERGAKVSGSRFYFLTGFGALLQLGLFQLAVRTATENGFTLVIPPVLVRPEIMSGTGFLGAHADEVYRVEADDLYLVGTSEVPLAGYHSGEILDLSEGPKRYAGWSSCFRREAGSYGKDTRGIIRVHQFDKVEGFVYCRPEEAEAEHDRLLGWQRQMLGLIEVPYRVIDIAAGDLGSSAARKFDCEAWVPTQQTYRELTSTSNCTTFQARRLGVRYRDENGKPQTAATLNGTLATTRWLVAILENHQQPDGSVRIPEALVPYVGTEVLTPKN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_MYCTU
Sequence: MTVAAGAAKAAGAELLDYDEVVARFQPVLGLEVHVELSTATKMFCGCTTTFGGEPNTQVCPVCLGLPGSLPVLNRAAVESAIRIGLALNCEIVPWCRFARKNYFYPDMPKNYQISQYDEPIAINGYLDAPLEDGTTWRVEIERAHMEEDTGKLTHIGSETGRIHGATGSLIDYNRAGVPLIEIVTKPIVGAGARAPQIARSYVTALRDLLRALDVSDVRMDQGSMRCDANVSLKPAGTTEFGTRTETKNVNSLKSVEVAVRYEMQRQGAILASGGRITQETRHFHEAGYTSAGRTKETAEDYRYFPEPDLEPVAPSRELVERLRQTIPELPWLSRRRIQQEWGVSDEVMRDLVNAGAVELVAATVEHGASSEAARAWWGNFLAQKANEAGIGLDELAITPAQVAAVVALVDEGKLSNSLARQVVEGVLAGEGEPEQVMTARGLALVRDDSLTQAAVDEALAANPDVADKIRGGKVAAAGAIVGAVMKATRGQADAARVRELVLEACGQG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: GCSP_BURM9
Sequence: MKLEHPDRLMNRTPLSLAALETHDAFAERHIGPDAASQQAMLDTLGFATRAALIDAVIPASIRRAETLPLGPFAQPKSEAEALAALRALADKNQVFRSYIGQGYYDTHTPAVILRNVLENPAWYTAYTPYQPEISQGRLEALLNFQQMVADLTGLEISNASLLDEATAAAEAMTLLQRVGKPQSNVFYVADDVLPQTLEVIKTRAKPIGIEVKSGPAADAAAANAFGVLLQYPGANGDVRDYRALADAIHAAGGHVVVAADILALTVLMPPGEWGADVAVGNTQRFGVPMGFGGPHAAYMAVRDEFKRQMPGRLVGVTVDAQGKPALRLALQTREQHIRREKATSNVCTAQALLAIMASMYAVYHGPRGLKTIALRVNRIAALLAAGIRHLGYATVNDTFFDTLTIDTGARTAQLHAFAQAKRINLRRAGDTRVGVSVDETTTRADLADLLTIFAQAAGATAPDIDALDAGLLPAPALPPSLERTSAYLTHHVFNRHHSETEMLRYLRSLSDKDLALDRSMIPLGSCTMKLNATSEMLPVTWPEFGRIHPFAPAEQTVGYREMIDQLEQMLVAATGYAAVSLQPNAGSQGEYAGLLIIHAYHESRGESHRDVCLIPASAHGTNPASAHMAGMKVVVVACDAQGNVDIADLKAKADAHSHDLAAIMITYPSTHGVFEQNVREICEIVHAHGGQVYVDGANMNAMVGLTAPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVGPHLAKFLPNQRSTGYARGEDGIGAVSAAPYGSASILPISWMYIAMMGAKNLTAATETAILNANYIAKRLAPHYPVLYSGPGGLVAHECILDLRPIKDSSGITVDDVAKRLMDYGFHAPTMSFPVPGTLMVEPTESESQEELDRFIAAMIAIRDEIRAVEEGRADREDNPLRHAPHTAAVVTANEWPHAYSREQAAFPVASLVANKYWPPVGRADNAYGDRNLFCSCVPVSDYA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.