PharMolix/UniProtQA huggingface dataset:
Protein: Y3618_JANMA
Sequence: MMLHIPEVLTAAQVVEIRKTIDTAEWVDGKATVGAQGAKVKRNRQLPELSATGLKVGQEILKALAGHPLFVSAALPMRYMPPLFNRYEGGEHYGFHVDGSVRSIPGSNLSLRTDLSCTLFLSEPEEYEGGELVVADTYGEHAVKLPAGDMILYPASSVHKVEPVTHGARISSFFWVQSMVADDGKRGLLFELDQNIQKLRARLGDCEEIIGLTGHYHNLLRQWAMV
What are the official names of this protein?
PKHD-type hydroxylase mma_3618.
Protein: DIR21_ARATH
Sequence: MASLYLLLLLPLFLALILAATITESKSFSTTVKAPYPGHKPDKLTHLHFYFHDIVSGDKPTSVQVANGPTTNSSATGFGLVAVVDDKLTVGPEITSEEVGRAQGMYASADQNKLGLLMAFNLVFTKGKFSDSTVAMYGRNPVLSKVREMPIIGGTGAFRFGRGYALAKTLVFNITSGDAVVEYNVYIWH
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
What are the official names of this protein?
Dirigent protein 21, AtDIR21.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: COXX_CERSK
Sequence: MTDIRITGIPKEAGFGDYVALLKPRVMSLVVFTALVGLLVAPVTVHPMIALTGILFIALGAGASGALNMWWDEDIDRVMKRTRNRPVPSGIVAPGEALGIGLALSGIAVVMLGLATNLFAAGLLAFTIFFYAVVYSMWLKRTTPQNIVIGGAAGAFPPMIGWAVATGGVSVESLFMFALIFMWTPPHFWSLALFMKSDYSDAGVPMLTVTHGRRVTRAHVLVYSLLLAPLAVAGAFTGIGGPLYLATALALNGWLLVGAVRIWRRDEAQAEADRYRVEKGFFRFSLYYLFLHFGAILAEAALKPYGLGGW
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCMB1_BOVIN
Sequence: MGKKLVMAQRRGETRALCLGVAMVVGAVITYYILGTTVLPLYQKSVWTQESTCHLIETNIRDQEELEGKRVPQYPCLWVNVSSVGRWAVLYHTEDTRDQNHQCSYIPSSLDNYQVARADVEKVRARFHENQDFFCFSTTRENETSVLYRRLYGPQSLLFSLFWPTFLLTGGLLIIVMVKINQSLSILAAQR
What is the function of this protein?
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel.  Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.  Increases the apparent Ca(2+)/voltage sensitivity of the KCNMA1 channel.  It also modifies KCNMA1 channel kinetics and alters its pharmacological properties.  It slows down the activation and the deactivation kinetics of the channel.  Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1.  Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2).  Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate (By similarity).
What are the official names of this protein?
Calcium-activated potassium channel subunit beta-1, BK channel subunit beta-1, BKbeta, BKbeta1, Calcium-activated potassium channel, subfamily M subunit beta-1, Calcium-activated potassium channel subunit beta, Charybdotoxin receptor subunit beta-1, K(VCA)beta-1, Maxi K channel subunit beta-1, Slo-beta-1, Slo-beta.
What is the protein family that this protein belongs to?
Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB1 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL14_CAUVN
Sequence: MIQMQTNLEVADNSGARRVMCIKVLGGAGRRYASVGDVIVVSVKEAIPRGRVKKGDVLRAVVVRVNQNLKRKDGSVIRFDKNAAVIVNKQSEPVGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL34_CORGB
Sequence: MAKGKRTFQPNNRRRARVHGFRLRMRTRAGRAIVAARRRKGRAKLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RLMH_ACIET
Sequence: MKLLIVAVGQRVPDWAQTAYDDYAKRFPPELKVELKAVKTEPRGSKTLETLYAAERERIEAAIPRGTRVVVLDERGTSLTTKALAQRLKDWQLGGDDVALVIGGPDGLEPAFRQAAHERIRLSDLTLPHAMVRVLLIEQLYRAWSVNAGHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_STACT
Sequence: MLYPPLNQLTSKVSSKYLIATVAAKRARELYDKPETALLEHYHSVKTVGKALEEIAAGKITPIEPELNESEFETKD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: TXVE_BOTIN
Sequence: MAAYLLAVAILFCIQGWPLGTVQGQVMPFMEVYRHSVCQTRETLVSILEEHPDEVSHIFRPSCVTALRCGGCCTDESLKCTATGKRSVGREIMRVDPHKGTSKTEVMQFTEHTDCECRPRSASGVNSRKHKRNPEEGEPRAKFPFV
What is the function of this protein?
Snake venom VEGFs may contribute to venom dispersion and prey subjugation by inducing vascular permeability and hypotension.  This protein induces vascular permeability probably through VEGF (VEGFR) signaling (PubMed:11517227).  This protein also induces a drastic hypotensive effect after intravenous injection (By similarity).  The hypotension is mediated by nitric oxide (NO), which is produced by VEGF-activated endothelium NO synthase (By similarity).  Also induces angiogenesis in vitro (By similarity).  Like other crotalid VEGFs, this protein interacts with VEGF receptor-1 (FLT1) with a high affinity, whereas it binds to VEGF receptor-2 (KDR) with a low affinity (By similarity).
What are the official names of this protein?
Snake venom vascular endothelial growth factor toxin, svVEGF, VEGF-F.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family. Snake venom VEGF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FXL12_MOUSE
Sequence: MATLFDLPDLVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLLRRYMASRLYSLRMGGYLFSGSQAPQLSPALMRALGQKCPNLKRLCLHVADLSMVPITSLPSTLRTLELHSCEISMIWLQKEQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRSLVLGGTYRVTETGLDASLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKIRLTVGGLSAQGLVFLEGMPVLESLCFQGPLITPDMPTPTQIVSSCLTMPKLRVLEVQGLGWEGQEAEKILCKGLPHCIVIVRACPKESMDWWM
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia (By similarity).
What are the official names of this protein?
F-box/LRR-repeat protein 12, F-box and leucine-rich repeat protein 12, F-box protein FBL12.
Protein: EME2_HUMAN
Sequence: MARVGPGRAGVSCQGRGRGRGGSGQRRPPTWEISDSDAEDSAGSEAAARARDPAGERRAAAEALRLLRPEQVLKRLAVCVDTAILEDAGADVLMEALEALGCECRIEPQRPARSLRWTRASPDPCPRSLPPEVWAAGEQELLLLLEPEEFLQGVATLTQISGPTHWVPWISPETTARPHLAVIGLDAYLWSRQHVSRGTQQPESPKVAGAEVAVSWPEVEEALVLLQLWANLDVLLVASWQELSRHVCAVTKALAQYPLKQYRESQAFSFCTAGRWAAGEPVARDGAGLQAAWRRQIRQFSRVSPAVADAVVTAFPSPRLLQQALEACSTERERMGLLADLPVPPSEGGRPRRVGPDLSRRICLFLTTANPDLLLDLGS
What is the function of this protein?
Interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures.
What are the official names of this protein?
Probable crossover junction endonuclease EME2.
What is the protein family that this protein belongs to?
Belongs to the EME1/MMS4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACYP_AERPE
Sequence: MEGVPSVRDSLVRARILVRGVVQGVFFRASMREEALRLGLSGWVRNLPDGESVEAVVEGRGDAVERIICWCLRGPPAARVRELRVELEPYKGEFRGFEIRY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: AATM_DANRE
Sequence: MALFKSSKILSSVGSQTPVLAVLQLRASSWWTEVQMGPPDPILGVTEAFKRDTNPKKMNLGVGAYRDDQGKPFVLSSVRKAEAQIAAKKLDKEYLPIGGLADFSKACVQLALGPDNEVLKSGRSITVQTISGTGSLRIGANFVSRFHNASRDVYLPKPSWGNHTPVFRDAGMQLKAYTYYEPKTCGFNLKGALDDISKIPEKSVILLHACAHNPTGVDPRPEQWKEMAALIKKRNLLVFFDMAYQGFASGDIDRDAWAVRYFIEQGHNILLSQSFAKNMGLYGERVGGFTVVCKDAEEAKRVESQLKILIRPIYSNPPMNGARIAATILNTPELYKEWLQEVKGMADRIIRMREMLVSNLKKEGSTHNWQHVTDQIGMFCFTGLKPEQVERLINEFSIYMTKDGRISVAGVTSANVEYLAHAIHAVTK
What is the function of this protein?
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA).  As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance.  Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism.
What are the official names of this protein?
Aspartate aminotransferase, mitochondrial, mAspAT, Glutamate oxaloacetate transaminase 2a, Glutamic-oxaloacetic transaminase 2a, mitochondrial, Kynurenine aminotransferase 4, Kynurenine aminotransferase IV, Kynurenine--oxoglutarate transaminase 4, Kynurenine--oxoglutarate transaminase IV, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Cell membrane.
Protein: MSMO1_PONAB
Sequence: MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE
What is the function of this protein?
Catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, which can be subsequently metabolized to cholesterol.
What are the official names of this protein?
Methylsterol monooxygenase 1, C-4 methylsterol oxidase, Sterol-C4-methyl oxidase.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ABHD4_HUMAN
Sequence: MADDLEQQSQGWLSSWLPTWRPTSMSQLKNVEARILQCLQNKFLARYVSLPNQNKIWTVTVSPEQNDRTPLVMVHGFGGGVGLWILNMDSLSARRTLHTFDLLGFGRSSRPAFPRDPEGAEDEFVTSIETWRETMGIPSMILLGHSLGGFLATSYSIKYPDRVKHLILVDPWGFPLRPTNPSEIRAPPAWVKAVASVLGRSNPLAVLRVAGPWGPGLVQRFRPDFKRKFADFFEDDTISEYIYHCNAQNPSGETAFKAMMESFGWARRPMLERIHLIRKDVPITMIYGSDTWIDTSTGKKVKMQRPDSYVRDMEIKGASHHVYADQPHIFNAVVEEICDSVD
What is the function of this protein?
Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE).  Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis.  Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains.  Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.
What are the official names of this protein?
(Lyso)-N-acylphosphatidylethanolamine lipase, Alpha/beta hydrolase domain-containing protein 4, Abhydrolase domain-containing protein 4, Alpha/beta-hydrolase 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.
Protein: RS22_ASHGO
Sequence: MTRTSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFEYIDDHRSGKIVVQLTGRLNKCGVISPRFNVKINDVEKWTANLLPARQFGYVILTTSAGIMDHEEAHRKHVAGKILGFVY
What are the official names of this protein?
40S ribosomal protein S22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RR8_GRATL
Sequence: MINDTIADMLTRIRNANLAKHQIVQVCSTKMTRNIIKVLQEEGFIYKFEEIGEDNNKYLLISLKYKGKRKKPVITSLKRISKPGLRVYANYKELPKVLGGIGIAIISTSKGVMSDYHARHYGLGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SELW_DANRE
Sequence: MTVKVHVVYCGGUGYRPKFIKLKTLLEDEFPNELEITGEGTPSTTGWLEVEVNGKLVHSKKNGDGFVDSDSKMQKIMTAIEQAMGK
What is the function of this protein?
Plays a role as a glutathione (GSH)-dependent antioxidant.  May be involved in a redox-related process.  May play a role in the myopathies of selenium deficiency (By similarity).
What are the official names of this protein?
Selenoprotein W, SelW.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family. Selenoprotein W subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3500_KLEP3
Sequence: MYPVDLHMHTVASTHAYSTLHDYIAEAKRKGIKLFAITDHGPDMADAPHYWHFVNMRIWPRLVDGVGILRGIESNIKNIEGEIDCSGPMLTSLDLIIAGFHEPVFPPQDRDTHTQAMIAAMASGKVHMISHPGNPKFPVDIPAIAEAAARYQVALEINNSSFISSRVGSEDNCRAIAAAVRDAGGWVALGSDSHTAFTLGEFTECRKILDAVDFPEERILNVSPRRLLNFLESRGMPAIPEFADL
What are the official names of this protein?
Probable phosphatase KPK_3500.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: RL5_ECOLI
Sequence: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5, Large ribosomal subunit protein uL5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MLTA_ECO57
Sequence: MKGRWVKYLLMGTVVAMLAACSSKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIGPEAGHRAGWYNHYGRVWVLKTAPGAGNVFSG
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Degrades murein glycan strands and insoluble, high-molecular weight murein sacculi (By similarity).
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase A, Mlt38, Murein hydrolase A.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: DUR3_ORYSJ
Sequence: MASGVCPPAELGFGAEYYSVVNGVCSRAGSYFGGRPVLTQAVGYAVVLGFGAFFALFTSFLVWLEKRYVGSQHTSEWFNTAGRSVKTGLIASVIVSQWTWAATILQSSNVAWQYGVSGPFWYASGATIQVLLFGVMAIEIKRKAPNAHTVCEIVRARWGTPAHLVFLTFCLLTNVIVTAMLLLGGSAVVNALTGVNVYAASFLIPLGVVVYTLAGGLKATFLASYIHSVVVHAVLVVFVFLVYTSSSKLGSPRVVYDRLMAVASAARDCSADLSRNGQACGPVAGNFKGSYLTMLSSGGLVFGIINIVGNFGTVFVDNGYWMSAIAARPSSTHKGYLLGGLVWFAVPFSLATSLGLGALALDLPLTAAEAAKGLVPPATATALMGKSGSVLLLTMLFMAVTSAGSAELVAVSSLCTYDIYRTYLNPGASGKQILRVSRAVVLGFGCFMGVLAVVLNVAGVSLGWMYLAMGVIVGSAVIPIALLLLWSKANAVGAMGGAVSGCALGVAVWLTVAKVQYGRVNLDTTGRNAPMLAGNLVSILVGGAVHAACSLLRPQHYDWGTSREMITTVESVHAALDDELKEERLVHAKRWIVRWGLVFTAVIVVAWPALSLPARRYSLGYFTLWAAVAIAWGTVGSVVIILLPVAESWTTITKVCAGMFTNDAVYDRLDDVNLRLRAIMGAMPEAEKRYRQLHETEMHPAGTHPANDDDDDNNNNQMMHS
What is the function of this protein?
High-affinity urea-proton symporter involved in the active transport of urea across the plasma membrane into root cells.  May play an important role in urea uptake by plant cells at low external urea concentrations.
What are the official names of this protein?
Urea-proton symporter DUR3, OsDUR3, High-affinity urea active transporter DUR3.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURC_MYCBP
Sequence: MSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRANRSAPGRPGVLG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y079_DEIRA
Sequence: MGGVSDERLDLVNERDEVVGQILRTDPALRWERVRVVNAFLRNSQGQLWIPRRSPSKSLFPNALDVSVGGAVQSGETYEEAFRREAREELNVEIDALSWRPLASFSPFQTTLSSFMCVYELRSDATPIFNPNDISGGEWLTPEHLLARIAAGEAAKGDLAELVRRCYREEE
What is the function of this protein?
Hydrolase that converts various nucleotide triphosphates (NTPs) to the corresponding nucleotide monophosphates and diphosphate, and nucleotide diphosphates to nucleotide monophosphates and inorganic phosphate.  Has a marked preference for cytosine ribonucleoside 5'-diphosphate (CDP) and cytosine ribonucleoside 5'-triphosphate (CTP).  Has lower activity towards the deoxyribose nucleotides dCDP and dCTP, and towards dGDP, TDP and UDP.
What are the official names of this protein?
Nudix hydrolase DR_0079.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: RS11_RHOPS
Sequence: MGKETTRIRRRERKNIASGIAHVNSSFNNTTITITDAQGNAIAWSSAGTMGFKGSRKSTPYAAQVAAEDVAKKAQEHGMRTLEVEVAGPGSGRESALRALQAAGFTVTSIRDVTTIPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CP1A2_RABIT
Sequence: MAMSPAAPLSVTELLLVSAVFCLVFWAVRASRPKVPKGLKRLPGPWGWPLLGHLLTLGKNPHVALARLSRRYGDVFQIRLGSTPVVVLSGLDTIKQALVRQGDDFKGRPDLYSSSFITEGQSMTFSPDSGPVWAARRRLAQDSLKSFSIASNPASSSSCYLEEHVSQEAENLIGRFQELMAAVGRFDPYSQLVVSAARVIGAMCFGRRFPQGSEEMLDVVRNSSKFVETASSGSPVDFFPILRYLPNRPLQRFKDFNQRFLRFLQKTVREHYEDFDRNSIQDITGALFKHSEKNSKANSGLIPQEKIVNLVNDIFGAGFDTITTALSWSLMYLVTNPRRQRKIQEELDAVVGRARQPRLSDRPQLPYLEAFILELFRHTSFVPFTIPHSTTRDTTLNGFHIPKECCIFINQWQINHDPQLWGDPEEFRPERFLTADGAAINKPLSEKVTLFGLGKRRCIGETLARWEVFLFLAILLQRLEFSVPPGVPVDLTPIYGLTMKHPRCEHVQARPRFSDQ
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2.  Metabolizes cholesterol toward 25-hydroxycholesterol, a physiological regulator of cellular cholesterol homeostasis.  May act as a major enzyme for all-trans retinoic acid biosynthesis in the liver.  Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid.  Primarily catalyzes stereoselective epoxidation of the last double bond of polyunsaturated fatty acids (PUFA), displaying a strong preference for the (R,S) stereoisomer.  Catalyzes bisallylic hydroxylation and omega-1 hydroxylation of PUFA.  May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent).  Plays a role in the oxidative metabolism of xenobiotics.  Catalyzes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.  Metabolizes caffeine via N3-demethylation.
What are the official names of this protein?
Cytochrome P450 1A2, CYPIA2, Cholesterol 25-hydroxylase, Cytochrome P450 isozyme 4, Cytochrome P450 LM4, Cytochrome P450-PM4, Hydroperoxy icosatetraenoate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: TRPC_MYCSS
Sequence: MSSATVLDSIIEGVRADVAAREAVVSLTEIKERAQRAKPPLDVMAALREPGIGVIAEVKRASPSRGALAQIGDPADLARAYQDGGARVISVLTEQRRFNGSLDDLDAVRAAVSIPVLRKDFIVRPYQIHEARAHGADMLLLIVAALEQPVLESLLERTESLGMTALVEVHTEAEADRALQAGARVIGVNARNLKTLEVDRDCFARIAPGLPSNVIRIAESGVRGPADLLAYAGAGADAVLVGEGLVTSRDPRSAVADLVTAGTHPSCPKPSR
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RS8_CLOP1
Sequence: MVMTDPIADLLTRVRNANSVRHEVVEVPSSSVKKAIVNILLQEGYLKGVEEYNDGVVPMMRLTLKYGANNERVITGLKRISKPGLRVYCKKDEVPRVLNGLGIALISTSKGLVVDREARKLGLGGEVICYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MU164_SCHPO
Sequence: MPGSPSQEPLAEAESNMLQRLEQLQMQTSNILKELHSTSIFTDSTTSQLHNGGENSVMDTEESSAIDKLSASLQQVNISSPSVPTSQSRVTQGQSLGNTQISNPTSKTNNVRAKARNIRNPSQRLRPSTSLARLSNNAPRIPKEASLHENSISSKESPSVTTSKHVATITKPSTSSIARMSSNARIAAIPRAKSSMAVRSPSRLGNGPNVRSPKVGFNAKSDDSPVVKSPGSNDKPSASPRISVRSLGNSSVVRPPTRTSTTRPLSRVNVTNASGSISKNSTSPSKVKVNASTKIVRPVSAAQTVRPGSRIFRENSASNTQRPNVSATSNSTVRVASSLAVRPVSRNAQARTPSRLEQREVNVKNSSAKIVRPGTSLGVRSPSRIQSTLSSRTTTGNVRTKAANIVRPSSSINRRPPSSINQRPPSNLRILAPSRSRATIHERPSSSILHRHAHSLTSSSFSTKTLATTKEIQNSPTLVESSTVVHHDPSYLQNQTSEINDTNHSSHSSPLDLNRMI
What is the function of this protein?
Involved in the cell polarity process and in regulation of microtubule growth.  Has a role in meiosis.
What are the official names of this protein?
Microtubule-associated protein mug164, Meiotically up-regulated gene 164 protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Microtubule-associated.