PharMolix/UniProtQA huggingface dataset:
Protein: ISPE_LISW6
Sequence: MKISITAPAKINLSLDALYKREDGYHEVEMVMTTIDLADRLSLERLDEDKIVLDVKAHFIPEDRRNLIYQAALLLKKRFNVKMGVRIIIDKHIPVSAGLAGGSSDAAAALKGLNIIWELGLSIEELAEISSEIGSDIAFCVYGGTALATGRGEKITALPNIPGCWIVLAKPSISVSTPTIYKELQVENVEHPNTKKMIESIKIGDLDGIFASTGNVLESVTLEKNPQVKRIKDRMMAFGAEAALMSGSGPTVFALIKQYSRAKRVYNGLRGFCEEVYMVRPWSESENETIN
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: TRX2_HHV6U
Sequence: METVYCTFDHKLSLSDISTLCKLMNIVIPIPAHHHLIGSGNLGLYPIVSSNKDYVHVRNVLRTMVVTILQKVEGNQLVLRKPVTGHQYAIKNTGPFPWEKGDTLTLIPPLSTHSEEKLLKLGDWELTVPLVVPTAIAAEINIRLLCIGLIAVHREYNEMQTIIDELCSIQYRDVLIKLPDIVNDKQSMYSMKTACISLSMITAMAPDIVRTYIDRLTLEDHSMLLIKCQELLSKRTTLNTQRCGQLHATEIKDELKKVKSVLTMIDQINSLTNEKTYFVVCDVSADNRMATCIYKN
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: HAOX1_ARATH
Sequence: MDQIVNVDEFQELAKQALPKMYYDFYNGGAEDQHTLNENVQAFRRIMFRPRVLVDVSNIDMSTSMLGYPISAPIMIAPTAMHKLAHPKGEIATAKAAAACNTIMIVSFMSTCTIEEVASSCNAVRFLQIYVYKRRDVTAQIVKRAEKAGFKAIVLTVDVPRLGRREADIKNKMISPQLKNFEGLVSTEVRPNEGSGVEAFASSAFDASLSWKDIEWLRSITKLPILVKGLLTREDALKAVEAGVDGIVVSNHGARQLDYSPATITVLEEVVHAVKGRIPVLLDGGVRRGTDVFKALALGAQAVLIGRPIVYGLAAKGEDGVKKVIDMLKNEFEITMALSGCPTIDDVTRNHVRTENERIKSML
What is the function of this protein?
Oxidase that catalyzes the oxidation of a broad range of 2-hydroxyacids to the corresponding 2-oxoacids, with a reduction of O2 to H2O2.  Displays the highest activity with the long-chain fatty acid 2-hydroxydodecanoate and has intermediate activity with 2-hydroxyhexanoate, 2-hydroxyoctanote, and the short-chain hydroxyacid (S)-lactate (L-lactate).  With much lower activity, it can also use glycolate, leucic acid, valic acid, and isoleucic acid as substrates in vitro.  Cannot use 2-hydroxyhexadecanoate or D-lactate as substrates.  May be involved in a general medium- and long-chain fatty acid catabolic pathway such as alpha-oxidation.
What are the official names of this protein?
Peroxisomal (S)-2-hydroxyacid oxidase GLO4, Glycolate oxidase 4, AtGLO4, GOX 4, lHAOX1.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: FGF7_HUMAN
Sequence: MHKWILTWILPTLLYRSCFHIICLVGTISLACNDMTPEQMATNVNCSSPERHTRSYDYMEGGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLAMNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQKGIPVRGKKTKKEQKTAHFLPMAIT
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation.  Required for normal branching morphogenesis.  Growth factor active on keratinocytes.  Possible major paracrine effector of normal epithelial cell proliferation.
What are the official names of this protein?
Fibroblast growth factor 7, FGF-7, Heparin-binding growth factor 7, HBGF-7, Keratinocyte growth factor.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNLJ_CAUVN
Sequence: MSQIPVADLTEAQAVEDLERLADLLATHDIAYHQEDNPTVSDAEYDALKRRNLDIETRFPHLVRDNSPSMRVGATRAEQFAPVEHGVPMLSLDNAFSNDEAIEFDARVRRFLRISPSETVAYTAEPKIDGLSASLRYEKGVLVQGATRGDGRVGEDVTANLRTIADIPHRLKGSGWPDVIEVRGEVYVELAAFAAFNKAAEEAGQRTYANPRNFAAGSLRQIDPKISAQRPLRFFGYAWGLVSEGFADSQWGALERLAEWGFVTTAPPAQRVLNAQGLLDIYAQFEVLRPTLGFDIDGVVYKVDDLELQRRLGFVSRSPRWAIARKFPAQRARTVLEAIDLQVGRTGAITPVARLKPVTVGGVSVTNATLHNGDEIARLDVRVGDTVVIQRAGDVIPQIVEVALDARPDPAPPPYEFPHVCPCPLQTPLAREVTASGQESVVRRCTGEFACPFQRVEHLRHFVSRRAFDIEGLGEKQLQAFFEEGWITEPADIFKLARDAEKLAVLREREGYGETSVANLVKGIEARRTIGMDRMIYGLGARDIGETTSTVLARNFDRFEDLQAAAEAAARALPGETYLELSTAPGVGPKALDMLVEAGKGGVVADPWPQTDDLELKIGHAVPKLTKPARAALAQRYGTWDAFADGLVAAASGAPGDDYLHLAAIDGVGPVAAQSLARFFAEDHNRQKVANLVAELDIQPVAKPKTDTAVAGKTIVFTGSLEKMTRDEAKAQAEGLGAKVASSVSKKTDLVVAGPGAGSKLKTATDLGIQVMTEDEWLELVAG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SYDND_RUBXD
Sequence: MHGTATNPYRTHTAGELRASNVGQRVRLAGWVHRRRDHGGLIFVDLRDRWGITQVTFDPERGEVFSAAERLRPEWSVSVEGEVVRRPEGNENPELPTGEIEVEASSLRVLNASETPPFEIDRERPVDELTRLRYRYLDLRRERMRENILFRDRVVRYIRRYLAERDFVEVETPLLTKSTPEGARDYLVPSRLYPGQFYALPQSPQQFKQLLMVAGLERYFQIARALRDEDQRGDRQPEHTQLDLEMSYTTQDEVLQLIEGLYTEIVERLTEKRVLFKPFPRLTYAEAMERFGSDKPDLRFGLELRDVSDLARSSEFKVFRNAVEAGGSVRGLAAGGLGDLSRRELDGLTEVAREGGARGLAHLRAEGKALKGPVAKFFSAEEQAALREALGARPGDWMFFVADRDPVVFESLNRLRLHLRDRLGLADRDALAFCWITDFPLFEYNEEEGRIEPMHHMFTMPREEDIPLLDTDPLAVTGQLYDLVANGVELASGSIRIHRPDLQQKVFSIIGIDEEEAERRFGTLLRAFRYGAPPHGGIAPGIDRLVMLLRDEPNIREVMAFPKTQAARDEMMDAPSPVSEEQLRELHISLCLPPEERRNP
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIM4_XENLA
Sequence: MATTKSSYRRIFGGNPRSSSSGSRYVTSSSRYSLGSSMRPGTSSSRMVYSTSASPAVFKSSSVRLRSSLPPARMADSVDFTLADAVNLEFKANRTNEKAEMIELNDRFANFIDKVRFLEQQNKILVAELEQLKGKGTSRIGDLYEEEMREIRRQLDQAINEKARVEVDRDNLGDDLQRLREKLQDEMIQREEAEGNLQSFRQDVDNASLARIDLERKVESLQEEIVFLKKLHDEEIRELQLQIQESHIQVDMDVSKPDLTAALRDVRQQYENVASKNLADAEDWYKSKFADLSEAANRNNEALRQAKQDTNDYRRQIQTLTCEIDAMKGSNESYERQMREMEENFALEAANYQDTIQRLQEEIQNMKEEMSRHLREYQDLLNVKMALDIEIATYRKLLEGEESRITIPVHSFSTMSLRETNLDSHPVDTHSKRTLLIKTVETRDGQVINESSQHHDDLDLDLE
What is the function of this protein?
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.  Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
What are the official names of this protein?
Vimentin-4.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: TRM44_XENLA
Sequence: MPELASVLVRDERSVLPGGFWAAVAVWLEKPQVLNKRLCGSTVGKKWDHVGEESESEGIDVETALAALLEDMSGPGRDEEMLKLISGYGKREEDSGSLTLRTLIPKSNPHFPSCQPRCEIVIRDLPNSVVTFLPLDEANQFKTNNIYQIRLAHVQDDEWSISLYTLCSEAWESDGVVYPKITWMKNELLSKLAKWSTEDKKSEFKSTLSLVPVDKYSRLYQNLKEKYRDMVKVWPEVTDPEKFVYEDVAIATYLLIIWEEERSQNQLKVKQSFVDLGCGNGLLVHILSNEGHPGRGIDVRRRKIWDMYGPQTILEESAILPNDDYLFPDTDWLIGNHSDELTPWLPVIASRSSYSCRYFVLPCCFFNFYGKYNRKSSKKTQYREYLDFVKEVGQQCGFNVEEDCLRIPSTKRVCLIGMSRTYPLTQEKRIDEQRTRYIKSQHTDSLHISTKSSLDKDDPPPLNCHAKNGQVDNVDSSLVQSEKLPGSWMPGFQPREKEEPIRNCALLPRDFIDETVLQVAKLLLYSNTKEKETPITDQSETVWNTGRSLTLREVAEHLHADTLQKLKNECGGLQTLLRNNHQVFKVINSNVSIRDWQKDTPTNTKKRKPEAKRTVPSDVLKTRLCWFYVHHPNGCPRVAKSCPYAHGAEELRPSFISRRKNPRNKLCT
What is the function of this protein?
Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
What are the official names of this protein?
Probable tRNA (uracil-O(2)-)-methyltransferase, Methyltransferase-like protein 19.
What is the protein family that this protein belongs to?
Belongs to the TRM44 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTCD_BOVIN
Sequence: MKGIKKSLTEEYLYLDFSHQKEGCIFPLHTSVTLFLLSYCDCTVFKVFLVLPGESTGISLLKNVPSEGVEIQTISRQELPPIVQSCCLPAVVERPDNFCRAGLAVVLRHIIQKSYEADPSKKEILELLGFKKTCLKACAEVSQWTRLCELTVPLAVENFLKESFDQPPTIPAAILELEKKLSEPVRVHNDDKLRRQKLKQQKAAGVGPSLAKEKTKSKGHRQETSEEGDSSSASLELKVAFSKLTIHKEPASANREPSYVRKAKASDLPPLDHVFAEGLYFTLADIVLLPCIHHFLVIICRKLSGKLVEFPLVAAWYQRIQEVPRVQTAASQCGIQFISLPELQTTSSQQPPNLDEAPSAEEQNDPSFIGGPRPTMTKLMEKGIEVMFSPHPCPTWTLDWDTLPAAVSPKEGKMSSDRALRKQQQLNNLVYMVTNQAKPGDRIVDFCSGGGHVGIVLAHVLPSCQVILIENKELSLIRAKKRSDELGLSNIWFIQANMEYFTGMFNIGVALHACGVATDMVIEHCLKTRASFVTCPCCYGFIQNTSKVNFPKSELFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEEHGFSVQVISMEPESCSPKNNMIVGVPI
What are the official names of this protein?
Glutathione S-transferase C-terminal domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the GSTCD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_PASMU
Sequence: MQALLPIEQYDSLLAEKQKKLTALLAPFHAPALAVFPSPVQHYRMRAEFRIWHDKGDFYHIMFDQRTRQRYRVDCFPMASQLINQMMDTLLPLLKTNRVLHHKLFQIDYLSTLSNKIIVSLLYHKTLDEEWEQAAKQLKASLLQQGFDLQLIGRASKQKICLEQEFVDEVLTVHGKSYVYRQVENSFTQPNAIVNQKMLEWAVDCTQNSEGDLLELYCGNGNFSIALAQNFRKVLATEIAKPSVAAAQFNIAENSIKNLQIIRMSAEEFTQAMNGVREFHRLKGIDLNAYECNTIFVDPPRAGLDEETVKLVQNYDRILYISCNPHTLCDNLQHLCQTHRIEKAALFDQFPYTEHMEAGVWLIRK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: PPT1_MOUSE
Sequence: MASSCSRRLLAAALLPWCCAAWALGHLDPPSPPPLVIWHGMGDSCCNPMSMGVIKKMVEKEIPGIYVLSLEIGKNMMEDVENSFFLNVNVQVNMVCQILEKDPKLQQGYNAIGFSQGGQFLRAVAQRCPTPPMMTLISVGGQHQGVFGLPRCPGESSHICDFIRKSLNAGAYSKLVQERLVQAQYWHDPIKESVYRNYSIFLADINQERCVNESYKKNLMALKKFVMVKFFNDSIVDPVDSEWFGFYRSGQAKETIPLQESTLYTEDRLGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFLK
What is the function of this protein?
Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation.  Prefers acyl chain lengths of 14 to 18 carbons.
What are the official names of this protein?
Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the palmitoyl-protein thioesterase family.
What are the subcellular locations of this protein?
Lysosome. Secreted.
Protein: S1PR5_RAT
Sequence: MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAAVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYATNILLSGPLTLRLSPALWFAREGGVFVALAASVLSLLAIALERHLTMARRGPAPAASRARTLAMAVAAWGLSLLLGLLPALGWNCLGRLEACSTVLPLYAKAYVLFCVLAFLGILAAICALYARIYCQVRANARRLRAGPGSRRATSSSRSRHTPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARACPVLLQADPFLGLAMANSLLNPIIYTFTNRDLRHALLRLLCCGRGPCNQDSSNSLQRSPSAVGPSGGGLRRCLPPTLDRSSSPSEHSCPQRDGMDTSCSTGSPGAATANRTLVPDATD
What is the function of this protein?
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P).  S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.  Is coupled to both the G(i/O)alpha and G(12) subclass of heteromeric G-proteins.  Displays antiproliferative effects in transfected CHO-K1 and HEK293 cells.
What are the official names of this protein?
Sphingosine 1-phosphate receptor 5, S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Nerve growth factor-regulated G-protein-coupled receptor 1, NRG-1, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDK_RUEST
Sequence: MALERTFSIIKPDATRRNLTGAINAKFEEAGLRIVAQKRIHMTKAQAGKFYAVHAERPFYDELCEFMSSAPVVVQVLEGEGAIAKNREIMGATNPADAAPGTIRAEFAESVGENSVHGSDAPETAAEEIAYFFSGLELVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_CLOAB
Sequence: MYAVIATGGKQYKVQEGDAIYVEKIAAEVDSTIELNEVLAVSKEDGLVLGKPVVEGAKVVAKVEAQGKSKKIIVFKYKRKKDYRRKRGHRQAYTKLVIEKIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PLMN_MOUSE
Sequence: MDHKEVILLFLLLLKPGQGDSLDGYISTQGASLFSLTKKQLAAGGVSDCLAKCEGETDFVCRSFQYHSKEQQCVIMAENSKTSSIIRMRDVILFEKRVYLSECKTGIGNGYRGTMSRTKSGVACQKWGATFPHVPNYSPSTHPNEGLEENYCRNPDNDEQGPWCYTTDPDKRYDYCNIPECEEECMYCSGEKYEGKISKTMSGLDCQAWDSQSPHAHGYIPAKFPSKNLKMNYCRNPDGEPRPWCFTTDPTKRWEYCDIPRCTTPPPPPSPTYQCLKGRGENYRGTVSVTVSGKTCQRWSEQTPHRHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSQLRWEYCEIPSCESSASPDQSDSSVPPEEQTPVVQECYQSDGQSYRGTSSTTITGKKCQSWAAMFPHRHSKTPENFPDAGLEMNYCRNPDGDKGPWCYTTDPSVRWEYCNLKRCSETGGSVVELPTVSQEPSGPSDSETDCMYGNGKDYRGKTAVTAAGTPCQGWAAQEPHRHSIFTPQTNPRAGLEKNYCRNPDGDVNGPWCYTTNPRKLYDYCDIPLCASASSFECGKPQVEPKKCPGRVVGGCVANPHSWPWQISLRTRFTGQHFCGGTLIAPEWVLTAAHCLEKSSRPEFYKVILGAHEEYIRGLDVQEISVAKLILEPNNRDIALLKLSRPATITDKVIPACLPSPNYMVADRTICYITGWGETQGTFGAGRLKEAQLPVIENKVCNRVEYLNNRVKSTELCAGQLAGGVDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVDWIEREMRNN
What is the function of this protein?
Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.
What are the official names of this protein?
Plasminogen.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasminogen subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface (By similarity).
Protein: RPOB_PSINU
Sequence: MILEENKGMFALPGFDLIQYEGFKRFINQGLMEELLKFPKIQDADQEVEFLLVGDQYKLREPSIKEKDAVYKCVTYSSELYVPARLTQKRNRRIREQILFMGSIPLMTSQGTFIINGVTRVLVNQIVRSPGIFYSREPDHKRIPLYTGTIISNWGGRFKLEIDGRMRIWARISKERKFSIITLLLALGLTRKDILNGVCYPNILLDLWKRQDKDIKSSEDAIIELYKNLYCVSGDVTFSESIRKELQRKLFKQRFELGQIGRRNPNNKLNLNVPENESFLLPQDLLAAIDYLIGIKYGIGTLDDIDHLKNRRVRSVANFLQGQLRLALTHLENSIRQTMHKAIKRKRSLTPKGLVISTPLLTTFKEFFGSHPLSQFLDQTNPLAEMIHKRRLSTLGPGGLTRRTASFQVRDIHPSYYGRICPIETSEGINAGLITSLALHARVNDYGYLHSSFYNISDDEEHIVYLSPAEDEYYRIATGNQLASNWGTQEKQVTLARYRQEFLTIAWEQVHFRSLFPLQYFSIGASLIPFLEHNDANRALMGSHMQRQAVPLLKPEKCIVGTGLEGQVALDSGSVTRSTQEGQIVYVDGAKITLSLNDNETIDTELITYKRSNNKTCIKERPIISTGTYLKEGQLLADGTATVGGELAPGRNILVAYMPWEGYNFEDAILISERLISEDIFTSLHIERYEIEVRITNQGIEEITKDIPHLDSYVLRHLDSNGLVVLGSWVETGDVLVGKLTPQEDSLRAPEGKLLQAIFGIQVADTKESCLKVPIGGQGRVIDARWVYKENILINNAKTIHIYILQKRKIRVGDKVAGRHGNKGIVSKILPRQDMPHLQDGTPVDMILSPLGVPSRMNVGQIFECLLGLAGDFMQRHYRITPFDERFEREASRKLVFSELCEASEKTRNPWLFEPDYPGKSRLIDGRTGDTFEQPVTVGKAYMMKLIHQVDDKIHARSSGPYALITQQPLRGRSRRGGQRVGEMEVWALESFGAAYILQEMLTLKSDHIQARYKVLGAIVTGKPIPKPNSVPESFRLLVRELRSLALNLNYFLISEKDLEREMKNV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RBL1C_NITHX
Sequence: MAVKTYQAGVTQYRQSYWQPDYVPLDTDILACFKITPQPGVDREEAAAAVAAESSCGTWTTVWTDLLTDLDYYKGRAYRLEDVPGDDTCYYAFIAYPIDLFEEGSVVNVFTSLVGNVFGFKAVRALRLEDLRFPIAYVKTCGGPPHGIQVERDRLNKYGRPMLGCTIKPKLGLSAKNYGRACYEALRGGLDFTKDDENINSQPFMRWRDRFDFVMEAVQKAEQETGERKGHYLNVTAPTPEEMYKRAEHAKEIGAPIIMHDYLAGGLCANAGLANWCRDNGILLHIHRAMHAVIDRNPHHGIHFRVLTKILRLSGGDHLHTGTVVGKLEGDRASTLGWIDLLRESFVPEDRSRGIFFDQDWGSMPGCFAVASGGIHVWHMPALVTIFGDDSVLQFGGGTLGHPWGNAAGAHANRVALEACVQARAEGRQLEKEGKDILTAAAAHSPELKIAMETWKEIKFEFEAVDQLAIANK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain 3, RuBisCO large subunit 3.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: CYSK_POPEU
Sequence: TPNSYILQQFENPANPKLIVAIFPSFGER
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4C_PARMW
Sequence: MIEFAVAGANDPIAATVPWLSLSILVPIVGALLVPFIPDSGDGKQIRWYALGVTLITFLITVSAYLNGYDPSLSGLQLSERVSWLPDLGLTWAVGADGLSMPLILLTSFITSLACLAAWPVSFKPRLFYFLLLAMDGGQIAVFAVQDMLLFFLAWELELIPVYLLLAIWGGKKRQYAATKFILYTAGSSLFILLAALAMGFFGGGTPSFEYTALAAKDFGSGFQLLCYAGLLIAFGVKLPIVPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALLRFNCELLPAAHAQFAPLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGVGSFSALGTSGAMLQMISHGLIGASLFFLVGATYDRTHTLQLDEMGGVGQKMRTMFALWTVCALASLALPGMSGFVSELMVFAGFATDEAYTLPFRVVICCLAAVGVILTPIYLLSMLREIFFGKEKQELVSHTNLVDAEPREVYIIGCLLVPIIGIGLYPRLMTDSYSRSIEALVGRDLGAMERITQPTAPLIRGQAPAVPAVLSAPSVPAS
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, NAD(P)H dehydrogenase I, chain 4, NDH-1, chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RS20_STRPZ
Sequence: MANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANPSEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: ATPG3_IPOBA
Sequence: MAMAALRREGRRLAAAPFTSPTPLNALRSSLVSPSEEIGLSGVRSISTQVVRNRMKSVKNIQKITKAMKMVAASKLRAIQTRAENSRGLWQPFTALLGDTPSVDVKKNVIITISSDKGLCGGINSTSVKTSRNIHKLNSGPEKENKYVILGEKAKAQLVRDSKKDIELIITELQKNPLNYTQVSVVADDILKNVEFDALRIVFNKFQSVVSFVPTMSTVLSPEVVERESESGGKLGDLDSYEIEGAESKSEVLQNLTEFQFSSVLFNAVLENACSEQGARMSAMDSSSRNAGEMLDRLTLTYNRTRQASITTELIEIISGASALEG
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and the central stalk which is part of the complex rotary element.  The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit gamma, mitochondrial, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein.
Protein: TVB53_HUMAN
Sequence: MGPGLLCWELLYLLGAGPVEAGVTQSPTHLIKTRGQQVTLRCSPISGHSSVSWYQQAPGQGPQFIFEYANELRRSEGNFPNRFSGRQFHDYCSEMNVSALELGDSALYLCARSL
What is the function of this protein?
Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) beta chain (PubMed:24600447).  Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
Probable non-functional T cell receptor beta variable 5-3.
What are the subcellular locations of this protein?
Cell membrane.