PharMolix/UniProtQA huggingface dataset:
Protein: CAP9_ADE40
Sequence: MSGFTEGNAVSFEGGVFSPYLTTRLPSWAGVRQNVVGSNVDGRPVAPANSTTLTYATIGSSVDTAAAAAASAAASTARGMAADFGLYNQLAASRLREEDALSVVLTRLEELSQQLQDMSAKMALLNPPANTS
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid exterior and forms triskelion structures consisting of three molecules that stabilize three hexon trimers at the center of each icosahedral facet and fixes the peripentonal hexons.  Dispensable for assembly.  During virus entry, recruits the anterograde motor kinesin-1 to the capsid docked at the nuclear pore complex thereby subjecting the docked capsid to a pulling force.  The resulting tension leads to capsid disruption, dispersion of capsid fragments toward cell periphery and eventually viral DNA entry into the host nucleus.
What are the official names of this protein?
Hexon-interlacing protein, Protein IX.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-interlacing protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Located in the canyons between the hexons on the outer surface of the capsid. Forms a sort of hairnet on the outer side of the virion. Present in 240 copies per virion.
Protein: ATP7_PICAN
Sequence: MSSVAKSTANKLDWTKIVSKLGLSGQTAAALTSFKKRNDEAKRILFELKQQPSNVDFAFYKSTLKNTAIVDKIQSDVSKFTPSKANLSKQLNLIESFEAKALENAKETESVVLAELTDLEKTLENIESARPFDQLTVDDVVKARPDVEEKVQDMVSKGRFEVPGYKEKFGDLVIM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169).  F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27791192).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).  Part of the complex F(0) domain and the peripheral stalk, which acts as a stator to hold the catalytic alpha/ATP1(3)beta/ATP2(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (PubMed:27791192).
What are the official names of this protein?
ATP synthase subunit d, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase d subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=The F-type ATP synthase complex is anchored in the mitochondrial inner membrane via the F(0) domain with the F(1) domain and the peripheral stalk extending into the mitochondrial matrix.
Protein: RL1_METMA
Sequence: MVERTILEAVKKVIEESPKRNFSESVDLAINLKNLDMNQPKNRVDEEVILPHGLGKELKIGVFAKGDVGLRAKAAGAAYVISDVELEELAADKNKARVLANECDLFIAETQFMPIIGKNLGIVLGPRGKMPIPLMPNKDIGELIQSKQNAVKLRSKDRLTFHVAVGRRNMNPDDLSENIETIMSRLERVLDKGKHNLRSVYVTTTMGKSERVV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ISY1_DICDI
Sequence: MARNEEKAKSMLNRYLQLKGTESKQEERRPYLSNECDSLVDAEKWRRQILKEITRGITEIQNSALDEYKIRDLNDHINKLVREKGHWERRILQLGGPNHRALAPKLFDADGKEPLGTGTYRYYGEAKNLPGVAELFEKPEQTLHGTEKKTRQDLYKYIDSDYYGYRDDEDGKLEEIEREYEKYAIEQNVENWKKQQRDKFQINTNRFNNNNIKNSIAINKNTENKDEINIDDDEENDDNNNNNNNNNTENTENIENIQEEEEKEDIKFKSYVSLPSTSQIETILLEKRKEELRKRYTQN
What is the function of this protein?
May play a role in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor ISY1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ISY1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MGSA_TRESO
Sequence: MRRKLRIALVAHDNRKADIVDWALNNAEMLSQHRLFGTGTTGTLVRESFMKRGIASDITCMHSGPMGGDAEIAALVVRKEIDFAVFFIDDLNPQPHEADIQMLLRQCRIHNIPIACNRYSADLMITSSLWDDAGYVPKDPIYAPFDRKAFEESLKVKE
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: CAP9_ADE03
Sequence: MSGSASFEGGVFSPYLTGRLPPWAGVRQNVMGSTVDGRPVQPANSSTLTYATLSSSPLDAAAAAAATAAANTILGMGYYGSIVANSSSSNNPSTLAEDKLLVLLAQLEALTQRLGELSKQVAQLREQTESAVATAKSK
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid exterior and forms triskelion structures consisting of three molecules that stabilize three hexon trimers at the center of each icosahedral facet and fixes the peripentonal hexons.  Dispensable for assembly.  During virus entry, recruits the anterograde motor kinesin-1 to the capsid docked at the nuclear pore complex thereby subjecting the docked capsid to a pulling force.  The resulting tension leads to capsid disruption, dispersion of capsid fragments toward cell periphery and eventually viral DNA entry into the host nucleus.
What are the official names of this protein?
Hexon-interlacing protein, Protein IX.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-interlacing protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Located in the canyons between the hexons on the outer surface of the capsid. Forms a sort of hairnet on the outer side of the virion. Present in 240 copies per virion.
Protein: ATPL_LACH4
Sequence: MSFMSEAFKYLAASIAAGLAALAAALGNGKVISKTLEGMARQPESADNLRATMFIGVGLIEAVPILAIVVAFLILFL
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LFTR_PROMH
Sequence: MPLFQLDEHDVTFPAPHLALKEPSGLLAIGGDISPARLKEAYQTGIFPWYTPHETPLWWSPDPRAVLPAGTLHIGRTLRKFLRQAPYTITLNQAFSDVIEACSVRDEGTWIGPDIKTGYRALHQQGEAHSVEVWEGDELIGGLYGVNVGAVFCGESMFSRRNNASKCAFVAFYNHFLRYGGQLFDCQVLNSHTAALGAIEIARDRYLEALSRWKKVIIDKKCWYQQSLEL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOE3_MOUSE
Sequence: MSAPLLKLGAVLSTMAMISNWMSQTLPSLVGLNTTRLSAPDTLTQISPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSSVLTGIQEEIGAYDYEELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKTSGTRFGAWMTDPLASEKNNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDLGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVMKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHIIKTEDDT
What are the official names of this protein?
Noelin-3, Olfactomedin-3, Optimedin.
What are the subcellular locations of this protein?
Secreted. Synapse. Note=Isoform 2 is secreted more efficiently than isoform 1.
Protein: SLBP_DROME
Sequence: MLCEDQHMSVENTPQKGSGSLNSSASSISIDVKPTMQSWAQEVRAEFGHSDEASSSLNSSAASCGSLAKKETADGNLESKDGEGREMAFEFLDGVNEVKFERLVKEEKLKTPYKRRHSFTPPSNENSRSNSPNSSNSSANGDAAAPKGGNNPHSRNSKKSGNFRAHKEEKRVRHNSYTSSTSSSSSYTEADPAILSRRQKQIDYGKNTAAYERYVEMVPKDERTRDHPRTPNKYGKYSRRAFDGLVKIWRKSLHIYDPPTQARDTAKDSNSDSDSD
What is the function of this protein?
Involved in histone pre-mRNA 3' processing and couples histone mRNA production with the cell cycle.  Both maternal and zygotic proteins play an essential and vital function for development.
What are the official names of this protein?
Histone RNA hairpin-binding protein, Histone stem-loop-binding protein.
What is the protein family that this protein belongs to?
Belongs to the SLBP family.
Protein: ILVD_POLSJ
Sequence: METKTIQLNPRSKNITEGKSRAPNRSMYYAMGYEEADFKKPMIGVANGHSTITPCNSGLQKLADAAIAGIEEAGGNAQVFGTPTISDGMAMGTEGMKYSLVSREVISDCIETCVQGQWMDGVLVIGGCDKNMPGGLMGMLRANVPAIYVYGGTILPGSYKGKDLNIVSVFEAVGENAAGRMSDEDLLQIERRAIPGTGSCGGMYTANTMSSAFEALGISLPYSSTMANPHDEKMNSARESAKVLVEAIKKDIKPRDLVTKKAIENAVAVIMATGGSTNAVLHFLAIAHAAGVDWTIDDFERVRQRTPVLCDLKPSGKYLAVDLHRAGGIPQVMKMLLAAGLLHGDCLTITGQTIAEVLKDVPEAPRADQDVIRPISNPMYAQGHLAILKGNLSPEGCVAKITGLKNPVMTGPARVFDDEQSALAAILAGKIKAGDVMVLRYLGPKGGPGMPEMLAPTGALIGAGLGESVGLITDGRFSGGTWGMVVGHVAPEAAAGGNIAFINEGDSITIDSKQLLLQLNISDAELEKRKVGWKAPAPRYNRGVQAKFAFNASSASKGAVLDDY
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RL36_THEP3
Sequence: MKVRPSVKPICEKCKVIKRKGRVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CRC1_HOMGA
Sequence: DKIPDFVVPGKCASVDRNKLWAEQTPNRNSYAGVWYQFALTNNPYQLIEKCVRNEYSFDGKQFVIKSTGIAYDGNLLKRNGKLYPNPFGEPHLSIDYENSFAAPLVILETDYSNYACLYSCIDYNFGYHSDFSFIFSRSANLADQYVKKCEAAFKNINVDTTRFVKTVQGSSCPYDTQKTL
What is the function of this protein?
Binds the carotenoid astaxanthin (AXT) which provides the blue coloration to the carapace of the lobster.
What are the official names of this protein?
Crustacyanin-C1 subunit.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RL23_CELJU
Sequence: MNQERIYKVLLGPVVSEKSAAVGEASNQVVFKVLADASKVEIKAAVQALFNTKVESVRVLNVKGKTKRTRYGVGKRSDWKKAYVRLEQGQEIDFAVAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HEXB_MICLU
Sequence: MIALSYKAFLNPYIIEVEKRLYECIQSDSETINKAAHHILSSGGKRVRPMFVLLSGFLNDTQKDDLIRTAVSLELVHMASLVHDDYIDNSDMRRGNTSVHIAFDKDTAIRTGHFLLARALQNIATINNSKFHQIFSKTILEVCFGEFDQMADRFNYPVSFTAYLRRINRKTAILIEASCHLGALSSQLDEQSTYHIKQFGHCIGMSYQIIDDILDYTSDEATLGKPVGSDIRNGHITYPLMAAIANLKEQDDDKLEAVVKHLTSTSDDEVYQYIVSQVKQYGIEPAELLSRKYGDKAKYHLSQLQDSNIKDYLEEIHEKMLKRVY
What is the function of this protein?
Catalyzes the condensation of three molecules of isopentenyl diphosphate with farnesyl diphosphate (FPP) to yield (all-E)-hexaprenyl diphosphate (HexPP; C30), the precursor of the prenyl side chain of menaquinone-6.  Large subunit Hexs-B catalyzes the condensation reaction and the final product chain length is cooperatively regulated by both the Hexs-A and Hexs-B subunits using the whole size of the hydrophobic cleft as a ruler.
What are the official names of this protein?
Hexaprenyl-diphosphate synthase large subunit ((2E,6E)-farnesyl-diphosphate specific), HexPS, Hexaprenyl diphosphate synthase, Hexaprenyl pyrophosphate synthetase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: GLGS_SALEP
Sequence: MNNNNVYSLNNFDFLARSFARMQAEGRPVDIQAVTGNMDEEHRDWFCKRYALYCQQATQAKRLELEH
What is the function of this protein?
Major determinant of cell surface composition.  Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
What are the official names of this protein?
Surface composition regulator.
What is the protein family that this protein belongs to?
Belongs to the GlgS family.
Protein: PKHM3_XENLA
Sequence: MEALEVDDISPALEVTEDFFNSFDKLENGVHQSHVFGIHQVPEFLGNEISNKMKEQADGQNANTSQRSIIWERCKSSLFDAKTMNGIHAKEQNESTKRTYSDDPLLSEKEKGTSTFNLLRRLDRPHSVNDSLDHLEDAPKFKPGHNRSRSDVSHIDWKNIRKPAPLQRSSSQGMHCTSPFSEPRNKNMEANNEVRSSFTNILKKGFLETRITPESFWKGCYAEISQYELHIYGSDYSGNHNATDTYHLSHIESITITGSHETKLVNVIMTDDRYLQLKADSAWEAIDWGQKLWEAICALNLVPNYRSIHQDILKKQNNFSDGIRGCMENNVNKLTPSAMNISNGNQKNIIKTGTLYRLTIQSNWKAFTFVLSNSHFAAYQPSCLDEDPLLSYNIDACIAVQMDMLDGYDSCFQVIFPQDVLRLRTETRQRAQEWMDAIISAANSARKSDQSLLVPLRKKSKENQSVKDLQRSKRQSVTTSFLSLLTSLALERGLTAQSFKCAGCQRPIGLSNEKAKVCSYSGWYYCSTCHVDDGFIIPARLIHNWDTSKHKVSKQAKEFLEYVYEEPLIDVHQENPLLYRHVDALAHVVRLRQQLKSLRAYLFSCRAVVAEDLRRRIFPREYLFQQIHLYSLSDLQQVVEGKLAPFLLKIIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEENSTSRCENCGAVFHSDCKVRTVPCPKCVRKELQKKQKSFWQQLDMDGSLDEACSMFELSYQST
What is the function of this protein?
May play a role during muscle differentiation.
What are the official names of this protein?
Pleckstrin homology domain-containing family M member 3, PH domain-containing family M member 3.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Cell membrane.
Protein: DJC12_RAT
Sequence: MDAILNYRPEGSEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENSKAVETFQKLQKAKEILSNAESRARYDHWRRSQMSMSFEQWEALADSVKTSMHWAVRSKKDLMLEGSEQTYTNTAQNKERSEQRETKQGDPDSTPEKMMQKESESPEKGISPQNPDSPGLSDWNCGHLHFRWSGDTPSELLRKFRNYEI
What are the official names of this protein?
DnaJ homolog subfamily C member 12, J domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_HELPY
Sequence: MEEYKDTLNLNTTTFSMKGNLSVNEPKTYAKWQEQQAFKRMQARKDNHGDFTLHDGPPYANGHLHLGHALNKILKDIVVKREYFKGKKIYYTPGWDCHGLPIEQQILERLEKEKTSLENPTLFREKCRDHAKKFLEIQKNEFLQLGVLGDFEDPYKTMDFKFEASIYRALVEVAKKGLLKERHKPIYWSYACESALAEAEVEYKMKKSPSIFVAFGLKKESLEKLKVKKASLVIWTTTPWTLYANVAIALKKDAVYALTQKGYLVAKALHEKLAALGVVDNEITHEFNSNDLEYLVATNPLNQRDSLVALGEHVGLEDGTGAVHTAPGHGEEDYYLGLRYNLEVLMSVDEKGCYDEGIIHNQLLDESYLGEHVFKAQKRIIEQLGDSLLLEQEIEHSYPHCWRTHKPVIYRATTQWFILMDEPFIQNDGSQKTLREVALDAIEKVEFVPSSGKNRLKTMIENRPDWCLSRQRKWGVPLAFFIDKRTNKPCFESEVLEHVANLFEKKGCDVWWEYSVKDLLPPSYQEDAKHYEKIMHILDVWFDSGSTFKAVLEDYHGEKGQSPSDVILEGSDQHRGWFQSSLLIGCVLNNQAPFKKVITHGFIVDEKGEKMSKSKGNVVSLDKLLKTHGSDVVRLWVAFNDYQNDLRVSQTFFTQTEQHYKKFRNTLKFLLANFSDMDLKNLERPHNFSPLDHFMLETLETISAGVNSAFEEHDFVKGLNILMAFVTNELSGIYLDACKDSLYCDSKNNEKRQAIQMVLLATASKLCYFLAPILTHTIEEVLEHSQALRIFLQAKDVFDLKDISVSEKLHLKEFKKPENFEAVLALRSAFNEELDRLKKEGVIKNSLECAIEVKEKALDENLVEELLMVSFVGIAKEKLSETPAFTLFKAPFYKCPRCWRFKSELENTPCKRCEQVLKER
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPSU5_ECOLX
Sequence: MSKAVIVIPARYGSSRLPGKPLLDIVGKPMIQHVYERALQVAGVAEVWVATDDPRVEQAVQAFGGKAIMTRNDHESGTDRLVEVMHKVEADIYINLQGDEPMIRPRDVETLLQGMRDDPALPVATLCHAISAAEAAEPSTVKVVVNTRQDALYFSRSPIPYPRNAEKARYLKHVGIYAYRRDVLQNYSQLPESMPEQAESLEQLRLMNAGINIRTFEVAATGPGVDTPACLEKVRALMAQELAENA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1B_PYRHO
Sequence: MSDFNLVGVIRVMPTDPDVNLDELEEKLKKVIPEKYGLAKVEREPIAFGLVALKFYVLGRDEEGYSFDEVAEKFEEVENVESAEVETVSRI
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: RPOA_COXBR
Sequence: MQNVLKSFLTPKNIQVQTISPCHFRILLEPLERGFGHTLGNALRRILLSSMPGAAIVQAEIDGVLHEYSSIEGVREDVVDVLLNLKGVAIKLEGREDAKLTLHKKGAGTVTAGDIQTESGVKIVNPDHVIAHITKDGEINMTLKAAMGRGYEPSSARSTGDQSRSVGLLLLDASYSPIRRVTYSVENARVEKRTDLDKLIIDLETDGTLDPEEAIRFAAAVLQHQLAAFVDLKQESDRDGGGKEGKVNPLLLRPVEDLELTVRAANCLKAESINYIGDLVQCTENDLLKTPNLGKKSLLEIKSVLAQKGLSLGMDLKGWPPADLTDQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: AHD2_TETPY
Sequence: LAKTVPLNDGTNFPIFGG
What is the function of this protein?
Specific for the oxidation of the 20-alpha hydroxy group of 17-alpha-hydroxyprogesterone and 17-alpha-hydroxypregnenolone.
What are the official names of this protein?
20-alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD.
Protein: LIPB_WOLPP
Sequence: MTEWLISNQFTDYNHSVKFMEAKIQQIYNNLSDELVWLLQHPPLYTAGIGATDDDIIEKLFPIYKTGRGGKYTYHGPGQRIIYLMLNLKKRNKCDIKLYIRDLSNWIINVLKHFNILGEFKEDRIGIWVNNKGVEEKIAAFGIRLRKWVTYHGIALNVSPNLSHYEGIIPCGLKDYGVTSMEKLGVKVSLCELDDILKQEFHKIF
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNHY_PSEFL
Sequence: MTQLISVNSRSYRLSSAPTIVICVDGCEQEYINQAIQAGQAPFLAELTGFGTVLTGDCVVPSFTNPNNLSIVTGAPPSVHGICGNFFFDQETQEEVLMNDAKYLRAPTILAEMAKAGQLVAVVTAKDKLRNLLGHQLKGICFSAEKADQVNLEEHGVENILARVGMPVPSVYSADLSEFVFAAGLSLLTNERPDFMYLSTTDYVQHKHAPGTPEANAFYAMMDSYFKRYHEQGAIVAITADHGMNAKTDAIGRPNILFLQDLLDAQYGAQRTRVLLPITDPYVVHHGALGSYATVYLRDAVPQRDAIDFLAGIAGVEAVLTRSQACQRFELPEDRIGDLVVLGERLTVLGSAADKHDLSGLTVPLRSHGGVSEQKVPLIFNRKLVGLDSPGRLRNFDIIDLALNHLA
What is the function of this protein?
Specifically hydrolyzes phosphonoacetate.  Does not have activity on other organophosphonates or acetates.
What are the official names of this protein?
Phosphonoacetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the alkaline phosphatase family. PhnA subfamily.
Protein: Y1704_AQUAE
Sequence: MKKDLFLISLVSFVFFIFGNWILSLTSLDEGRNFYATLHMLRTGDFIVPYYNCNYRFEKPPMLYWLGSLSFLIFGISEFSARLISGLSAFGTTLLIYFITLKHVSREKALLSALTFPLFIHTWIESRAYVPEFTLVFFSTLGVYLFSIDRFTLGWTALALAFLTKGPVGVILPIGIYLLWRRDLKFLNFKGVLLFILIGFSWYFLMIYKFGFNFFFKFFIFENIYRFTGTYQIHNMPIYFYPLVILVSSILFLPVFLKILKDFDKRLLPFAGWFLLVLVFYSLSKNKLHHYILFSYPALSVIIGFYLTKRYIKYAYIVGSFLLLILMFGVYIYEQKRFTPKAVDFLKNSEPQKLYFYKHENSAIVAYLYRCITKENKFKKGDYVITKKKYLRDFKNYKLLIEGLEFEGKEVLIKVE
What are the official names of this protein?
Uncharacterized protein aq_1704.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PET8_ASHGO
Sequence: MDSTFLASLVSGAAAGTSTDVVFFPIDTLKTRLQAKGGFFHNGGYRGIYRGLGSAVVASAPGASLFFVTYDSMKQQLRPVMGRWTASEQLAEVLTHMLSSSLGEMSACLVRVPAEVIKQRTQTHHTNSSLQTLRLILRDPTGEGVVRGLYRGWWTTIMREIPFTCIQFPLYEYLKKKWAAYAEIERVSAWQGAVCGSLAGGIAAAATTPLDVLKTRMMLHERRVPMLHLARTLFREEGARVFFRGIGPRTMWISAGGAIFLGVYEAVHSLF
What are the official names of this protein?
Putative mitochondrial carrier protein PET8.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PUR5_STAA2
Sequence: MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDASRALKILAEQNVEAYQIGHIVKNESTAIELLGV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTAA_STAAN
Sequence: MFGKKNLKWLGVVATLMMTFVQLGGALVTKTGSADGCGSSWPLCHGALIPEFFPIDTIIELSHRAVSALSLLMVLWLVITAWKHIGYIKEIKPLSIISVGFLLLQALIGAAAVIWQQNDYVLALHFGISLISFSSVFLITLIIFSIDQKYEADELYIKKPLRRLTWLMAIIIYCGVYTGALVRHADASLAYGGWPLPFHDLVPHSEQDWVQLTHRIMAFIVFTIIMITYIHAVKNYPNNRTVHYGYTAAFILVILQVITGALSIMTNVNLIIALFHALFITYLFGMTTYFIMLMLRSVRSDKQ
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TIG_PSESM
Sequence: MQVSVENTSALERRMTIGVPAERIETEVNKRLQQTARKAKIPGFRPGKVPMSVIRQRYEDGARQEALGDLIQATFYEAVVEQKLNPAGAPAVEPKSFEKGKDLEYVATFEVFPEFTVAGFDTIAVERLSADVADSDLDNMLEVLRKQNVRFEVADRAAQNEDQLNIDFEGKVDGEVFAGGSATATQLVLGSGRMIPGFEDGLVGAKAGEERVLNVTFPEDYQNLDLAGKAAEFTVTVNTVSEPKLPELNEEFFKQFGIKETGIEGFRTEVRKNMERELRQAIKSKVKNQVMDGLLAANPIEVPKALLENEVNRLRVQAVQQFGGNIKPDQLPAELFEEQAKRRVELGLIVAEVVKQFDLKPDDARVREMIQEMASAYQEPEQVVAWYYKNEQQMNEVRSVVLEEQVVDTVLQKASVTDKSVSYEEAVKPVEAAKAD
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.