PharMolix/UniProtQA huggingface dataset:
Protein: EFGM_KLULA
Sequence: MFKRVGLIAGIAGPVAGSSRFSAVSFSKRAFSASSKRCTYEEERAVLDEIQPLLSEKDIDASKKLRNIGISAHIDSGKTTFTERVLYYTGRIKAIHEVRGRDNVGAKMDSMDLEREKGITIQSAATYCSWDKDNESYHFNLIDTPGHIDFTIEVERALRILDGAVLVVCAVSGVQSQTVTVDRQMRRYNVPRVTFINKMDRMGANPFRSIEQINNKLRIPAAAIQVPIGAESELKGVVNIIDRVAIYNEGSNGEKLVTGPVPEDLKDLVEEKRALLIETLADVDDEIAEIFLEEKEPSVDEIKAAIRRATIARKFSPVLMGSALANTGIQNVLDAIVEYLPNPSEVLNTGLDIAKDETKVNLIPSSTQPFVGLAFKLEEGKYGQLTYIRVYQGKMRKGGYITNVKTGKKVKISRLVRMHSNDMEDVDEVGAGEICATFGIDCSSGDTFTDGTLKYSMSSMFVPDAVISLSITPKSKDSTNFSKALNRFQKEDPTFRVRFDPESKETVISGMGELHLEIYVERMRREYNVECVTGKPQVSYRESIQSSAEFDYTHKKQSGGAGQYGRVMGNLSHIENSNTNNFETAIVGGRIPDKYLAACAKGFEEACEKGPLIGHRVLGVNMLINDGAIHAVDSNELAFKTATMAAFRQAFLESQPVILEPIMNVSVTSPNEFQGNVIGLMNKLQAVIQDTENGQDEFTITAECPLNTMFGFATSLRASTQGKGEFSLEFKHYAPASPQLQKQLIADYQKKQQQK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EFTU1_PSYWF
Sequence: MAKAKFERNKPHVNVGTIGHVDHGKTTLTAAIATVAAKTFGGEAKDYAAIDSAPEEKARGITINTSHIEYDTADRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSATDGPMPQTREHILLSRQVGVPYIMVFMNKCDMVDDEELLELVEMEVRELLSDYDFPGDDTPIIKGSALEALNGKDGKYGEPAVIELLQTLDTYIPEPERDIDKPFLMPIEDVFSISGRGTVVTGRVESGIVKVGDEIEIVGIRDTQKTTCTGVEMFRKLLDEGRAGENCGVLLRGTKREDVQRGQVLAKPGSITPHTKFDAEVYVLSKEEGGRHTPFLNGYRPQFYFRTTDVTGAISLQEGTEMVMPGDNVEMSVELIHPIAMDKGLRFAIREGGRTVGAGVVANVKD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_FRUSA
Sequence: MSRIGYKTIVIPEGVTVTRDEDVITVKGPKGELSETFSPDVAMNVNGNEINFEPTGKYDNKMCALHGTQRANLANMIEGVEKGFNKTLKLVGVGYRTQLKGSDLILNVGYSNPVDVKVPEDIDVKVPDNTTIEIAGINKQHVGDFAAKVREIRSPEPYKGKGIRYENEHITLREGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PEX19_YEAST
Sequence: MNENEYDNFDDLDDLLDEDPTKLDEAEPDDVQAKGSVYNDSENKEKNAESKDSDGVQVANESEEDPELKEMMVDLQNEFANLMKNNGNENNVKTEDFNKLISALEEAAKVPHQQMEQGCSSLKSNSTDKGTVNGSNPGFKNIVSNTLDRLKENGNKVDTSLAEETKESQRSGQNNNIDDILSQLLDQMVASGGKESAENQFDLKDGEMDDAITKILDQMTSKEVLYEPMKEMRSEFGVWFQENGENEEHKEKIGTYKRQFNIVDEIVNIYELKDYDELKHKDRVTELLDELEQLGDSPIRSANSPLKHGNEEEELMKMLEIDGNDPNLGNLDKELTDGCKQQ
What is the function of this protein?
Required for proper post-translational import and stabilization of peroxisomal membrane proteins (PMPs).  Acts as a cytosolic import receptor for PMPs and delivers them to the docking factor PEX3 at the peroxisomal membrane for subsequent insertion into the membrane.  Acts as a chaperone in stabilizing or maintaining PMPs in the lipid bilayer.  Directs PEX17, a peripheral component of the peroxisomal matrix protein translocation machinery, to peroxisomes.  Stabilizes VPS1, a protein required for peroxisomal fission, at the peroxisomal membrane.  Also acts in conjunction with PEX3 in the formation of peroxisomes from preperoxisomal compartments at the endoplasmic reticulum during de novo peroxisome synthesis, probably via the import of additional PMPs.
What are the official names of this protein?
Peroxisomal membrane protein import receptor PEX19, Peroxin-19.
What is the protein family that this protein belongs to?
Belongs to the peroxin-19 family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum membrane. Note=Predominantly cytoplasmic (PubMed:9418908). Concentrates in a PEX3-dependent manner to defined foci on the endoplasmic reticulum membrane, which then bud off to form newly sythesized peroxisomes (PubMed:16009135).
Protein: TRMD_BACHK
Sequence: MKIDILTLFPDMFTGVFGSSILKKAQEKEAVELRVVNFRDYTTSKHNSVDDYPYGGGAGMVLTPQPIFDAVEDLTKETERKPRVVLMCPQGERFTQKKAEELAEEEHLIFVCGHYEGYDERIREHLVTDEISIGDYVLTGGELASMVITDSVVRLLPGVLGNHASQVEDSFSTGLLEHPHYTRPADFRGMKVPDVLMSGNHKNIDEWRHKESLRRTYTRRPDLLEERELSKQEKKWLEQIKEGK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPTC8_MOUSE
Sequence: MADRFSRFNEDRDFQGNHFDQYEEGHLEIEQASLDKPIESDNIGHRLLQKHGWKLGQGLGKSLQGRTDPIPIVVKYDVMGMGRMEMELDYAEDATERRRVLEVEKEDTEELRQKYKDYVDKEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSSRSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFRPTTVAVDEDGGEEDKDESSTNSGASAVSSCGFGADFSTDKGGSFTSVQITNTTGLSQAPGLASQGISFGIKNNLGPPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGSSEDGTKADEKSSDQGVQKVGDTDGTGNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGTGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQMEGDHSAHSKSAPENRKSSSPKPQGCSKTAASPGAERTVSEASELQKEAAVAGPSEPGGKTETKKGSGGGEDEQSVESRETSESPMCESNPKDISQATPATKAGQGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDAKAKGTEKPKDVAGSSKDHLQSLDPREPNKSQEEEQDVVLSSEGRVDEPASGAACSSLNKQEPGGSHMSETEDTGRSHPSKKEPSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAAADSERGPKSEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGNSGKKDDGGGGSSCQDHSGRKHKGEPPTSSCQRRANTKHSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEEEEEEEEDEDSGSEHSRSRSRSGHRHSSHRSSRRSYSSSSDASSDQSCYSRQHSYSDDSYSDYSDRSRRHSKRSHDSDDSDYTSSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKGSWGHESPEERRSGRRDFIRSKIYRSQSPHYFQSGRGEGPGKKEDGRGDDSKGAGLPSQNSNTGTGRGSESDCSPEDKNSVTARLLLEKIQSRKVERKPNVCEEVLATPNKAGLKYKNPPQGYFGPKLPPSLGNKPVLPMIGKLPATRKSNKKCEESGLERGEEQEHSEPEEGSPRSSDAPFGHQFSEEAAGPLSDPPPEEPKSEEATADHSVAPLGTPAHTDCYPGDPAISHNYLPDPSDGDTLESLDSGSQPGPVESSLLPIAPDLEHFPNYAPPSGEPSIESTDGTEDASLAPLESQPITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASTALAPATPALQPIHIQQPATASATSITTVQHAILQHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLASHPIHIIPASAIHPGPFTFHPVPHAALYPTLLAPRPAAAAATALHLHPLLHPIFSGQDLQHPPSHGT
What are the official names of this protein?
G patch domain-containing protein 8.
Protein: PTH_ECO5E
Sequence: MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAKFFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_CAUSK
Sequence: MHSLDTYAADKIERLEAASLLRRLKPTQRSAGVVVERDGRKLLSFSCNDYLGLAHHPKVKAAAQAAIETYGAGSGASRLVTGDHPLLSELEARLARLKGAEACVVFGSGYLANTGLIPTFAGKGDIVLLDELAHACIWAGAQLSGARIIPFAHNDTDHLAALLAEHRSSARHAIVATDGVFSMDGDIAPLDWLSAVCEANDAWLLSDDAHGVGVLAQGKGSAALFPEAQIPFQMGTLSKALGSYGGYVCASQAVVDLLKTRARTLVYSTGLPPAAAAAALAALDIVEAEPALTALPLAKARAFTQAVGLPPAASPIVPVIIGEAQDALDASRALEAEGFLVVAIRPPTVPAGAARLRIAFSAEHPDAEIARLAELVRPYVKAR
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: ATPF_YERPA
Sequence: MNLNATILGQAIAFVLFVIFCMKYVWPPIMAAIEKRQQEIADGLSSAERAKKDLDLAQANATDQLKKAKAEAQVIIEQASKRKAQILDEAKAEAEQERNKIVAQAQAEIDAERKRAREELRKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PLEK_RAT
Sequence: MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNNPKGMIPLKGSTLTSPCQDFGKRMFVLKITTTKQQDHFFQAAYLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDPEKGIKELNLEKDKKVFNHCFTGSGVIDWLVSNKLVRNRQEGLMISASLLSEGYLQPASDLSKNAADGIAENPFLDNPDAFYYFPDSGFFCEENSSDDDIILKEEFRGIIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAIHLRGCVVTSVESNPDGKKSDEENLFEIITADEVHYYMQAATAKERTEWIKAIQVASRTGK
What is the function of this protein?
Major protein kinase C substrate of platelets.
What are the official names of this protein?
Pleckstrin.
Protein: GLB1_CHITH
Sequence: MKFLILALCVAAAMAGPSGDQIAAAKASWNTVKNNQVDILYAVFKANPDIQTAFSQFAGKDLDSIKGTPDFSKHAGRVVGLFSEVMDLLGNDANTPTILAKAKDFGKSHKSRASPAQLDNFRKSLVVYLKGATKWDSAVESSWAPVLDFVFSTLKNEL
What are the official names of this protein?
Globin CTT-I/CTT-IA, Erythrocruorin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DFA16_MOUSE
Sequence: MKTLILLSALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSVSFGDPEGTSLQEESLRDLVCYCRSRGCKGRERMNGTCRKGHLMYTLCCR
What is the function of this protein?
Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
What are the official names of this protein?
Alpha-defensin 16, Defensin-related cryptdin-16.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURA_IDILO
Sequence: MDKFKIRGGQPLSGSVTISGAKNAALPILMASLLPSEKITLSNVPDLHDVDTTLELLDCLGISHSNLNNNSVCIDPTTLNHFKAPYDLVKTMRASILVLGPLLAKTGKAEVSLPGGCAIGARPVNLHIEGLRKMGAHIDVENGYIKASVEGRLQGAEILLDTVSVTGTENLMMAAVLAEGETVIENAAREPEVIDLANFLNSLGANVRDAGSDTIHITGVNKLHGGEYSVMPDRIETGTFLVAALATGGSVRCEKTDPASLDAVLKKLEEAGATIDKGDNWIAIQSHGRPKAVNIITAPHPAFPTDMQAQFCALNAIAEGTAGIRETIFENRFMHIPELRRMGANVESEGNTALCHGVDELTGAEVMCTDLRASASLVIAGLVATGETVVERIYHIDRGYEGIEKKLQGLGADIERVTA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB_CLOAB
Sequence: MEKIKVIVVDDSVLMRRLICDMLESNDNIEVIGTAINGQDLLNKLKVMKPDVITLDIEMPVMNGIETLKAVKSLKIDIPIIVFSSISQKGMKYTMECLYLGAFDFIPKPEKPFELSKMKDDLIKRIRVAYSQNTNKNPAPINPVIRRETNRISSDSIEAVVIGASTGGPKALYKVITKFPKDMNVPVFVVQHMPVGFTKAFADRLNDNSAIEVKEATDGETYRKGVVYVAPGGYHMEVDSNSRIKLTKEPPIWGVRPAVDKLFISASKIFKSHIVSAVLTGMGKDGSNGTGIIKDNGGVTISESETTCVIYGMPKAAFETGKVDLVVPIDNVADEIIKIVRGLRR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_PROMI
Sequence: KRAVQSEKRRQHNASRRSMMRTYIKKVYAAVASGDKEAAQKAFNDMQPIVDRQATKGLIHKNKAARHKANLQ
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: 4CL2_NARPS
Sequence: MITIAESHPQIHHSPPDTTAPSTPPTATIFRSRLPDIVLSNHLPLHEYLFENTLTSPSPCIISASTGRSYSFAETHLLSRKTASFLSSRCGVRRGGVVMLLLHNCPEFVFSFLGSSMLGAVTTAANPFCTPQEIKKQLLASGATVIITQSAYASKISRDDDVEDLIVVTVSDNELERHAAPPEGCVSFSEVESADEDAVPDAVGVGPEDAVAMPFSSGTTGLPKGVVLTHKSMTSSVGQIVDGENPNLHLRKGEDVLLCVLPLFHIFSLNSVLLCGLRTGAAVVIMARFEMEGMLETIQRWGVSVAAVVPPLVLALAKNPLVEKYDMGTVRMVLSGAAPLGKELEAVLKGRLPQAVLGQGYGMTEAGPVISMSPGFAKQPTPVKSGSCGTVVRNAELKVMDPETGFSLGRNQPGEICVRGPQIMKGYLNDPEATSATIDVEGWLHTGDVGYVDDDDEVFIVDRVKELIKFKGFQVPPAELEALLLGHPSIADAAVIPQNDEVAGEVPVAFVVPSKSSDLTEEIVKEFISKQVVFYKRIHRVYFIHAIPKSPSGKILRKDLRAKVASFSS
What is the function of this protein?
Produces CoA thioesters of a variety of hydroxy- and methoxy-substituted cinnamic acids, which are used to synthesize several phenylpropanoid-derived compounds, including anthocyanins, flavonoids, isoflavonoids, coumarins, lignin, suberin and wall-bound phenolics.
What are the official names of this protein?
4-coumarate-CoA ligase 2.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: MNTH_CROS8
Sequence: MNHTRVEQNRGRTARKLRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQVLSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQKRGQKPLEKVIGGLLLFVAAAYIVELFFSQPKLAELGKGMLIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQNLHDGSRKERYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTKVAELDQAYLTLEPLLSHAAATIFGLSLVAAGLSSTVVGTLAGQVVMQGFVRFSIPLWVRRAVTMAPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLFFTSNKALMAELVNTPWVKRTGWAIVVLVVALNIWLLVGTALGL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ALKH_BACSU
Sequence: MESKVVENRLKEAKLIAVIRSKDKQEACQQIESLLDKGIRAVEVTYTTPGASDIIESFRNREDILIGAGTVISAQQAGEAAKAGAQFIVSPGFSADLAEHLSFVKTHYIPGVLTPSEIMEALTFGFTTLKLFPSGVFGIPFMKNLAGPFPQVTFIPTGGIHPSEVPDWLRAGAGAVGVGSQLGSCSKEDLQAVFQV
What are the official names of this protein?
KHG/KDPG aldolase.
What is the protein family that this protein belongs to?
Belongs to the KHG/KDPG aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLHL8_HUMAN
Sequence: MASDSMSSKQARNHITKGKRQQQHQQIKNRSSISDGDGEDSFIFEANEAWKDFHGSLLRFYENGELCDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAKQTLIEIRDFDGDAIEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRIDLMDMADQYACDHFTEVVECEDFVSVSPQHLHKLLSSSDLNIENEKQVYNAAIKWLLANPQHHSKWLDETLAQVRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSRAVPDFEYSIRTTPRKHTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSMEMFDPLTNKWMMKASMNTKRRGIALASLGGPIYAIGGLDDNTCFNDVERYDIESDQWSTVAPMNTPRGGVGSVALVNHVYAVGGNDGMASLSSVERYDPHLDKWIEVKEMGQRRAGNGVSKLHGCLYVVGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFDPVLNRWELVGSVSHCRAGAGVAVCSCLTSQIRDVGHGSNNVVDCM
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN.
What are the official names of this protein?
Kelch-like protein 8.
Protein: SYA_ERYLH
Sequence: MQSTNDIRRSFLDYFTGAGHAEIASAPLVPYNDPTLMFVNAGMVPFKNVFTGLETPPAPTATSSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEQAIEHAWTLLTREWGIDAARLTATVYHTDDEAYDFWRKIAGLPEERIIRIATKDNFWAMGDDGPCGPCSEIFFDHGDHIFGGPPGSPEEDGDRFVEVWNLVFMQHEQTGGEITGDLPNKNIDTGMGLERIAAVMQGVHDNYDTDTFKELIGASEGLTGVKAEGDQAASHRVIADHLRSTSFLIADGVLPSSEGRGYVLRRIMRRAMRHAHLLGASEPLMHRLVPALVTEMGQAYPELTRGQALIEETLEREEARFRQTLEKGLRLLDDATGDMSEGDTLDGETAFKLYDTYGFPYDLTEDALRPRGIAVDETGFASAMQRQKDAARAAWKGSGQAADSEVWFDIAEREGATEFTGYTSTSGEGRVVALVKNGKEVDSASAGDEVVILTNQTPFYGESGGQTGDAGTMSTPDGVKVEVTDTGKPLGRLHTHQAKIQSGTVLKGDTLHLDVDVDRRDRVRANHSATHLVHAALRNRLGEHVTQKGSLVAEDRLRFDFSHPKPLSEDDIAAIEAEVNEEIRANETVTTRLMSPDDAVDAGALALFGEKYGEEVRVLSMGRRSKEGRNYSVELCGGTHVRATGDIQLFRIISESAVSSGVRRIEALTGDAARQWLVRREEALKSAASALRTNPEEVAERVAALLDERKALEKELADARKQLALGGGGSQVAQSQDETIGDVTFSGQVINGLNPKDLRGLLDEAKQRMGSGIAAICAVNEGKAAFAAAVTDDLTDRYNAVDLVRAGVEVLGGKGGGGRPDMAQGGGPDGLKAEAALNAVRERLASAAA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMC_RHORT
Sequence: MSDGDGGGEQGGGGPAEAEESALVLGRLLDRGAWRLKVAGVEKPRRDARLLAGHVLGLSPGAVLLADDRVVTPEEAQALEAVIARRETREPVSRILGHRGFWRFDLALGADTLDPRPDTETLVEAGLAVLEGCGGRILDLGTGSGCILLALLADRPGAIGLGIDIAPGAVRVALRNARALGLERRALFAVGDWAAAVAGPFDLIVSNPPYIPSADIAALEPEVARFDPSRALDGGADGLDPYRILAAQVPALLAPAGVLAVEFGQGQARDVAGLLEVGGLCPYEIKKDLSGEERCLLARRRAAGPLPPIHIDAKPSAPGNGPTKA
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: PPAC_ARCFU
Sequence: MEHVVYVVGHKNPDTDSVCSAIAFAYLWNKWKEGGNVAKMMKIEAEAKPVIQGDVNPETKYVLEKFGFEVPEIMTNGEGKKVALVDHSEKAQTVDGIDKAEVVAIVDHHKIGDVTTPQPILFVNLPVGCTATVIKLLFDKTGVEIPKDIAGILLSSILSDTVIFKSATTTELDKEVAEELAKIAGIDDLTKFGVEIKAKLSAVDDLTAMDIIKRDYKDFDMSGKKVGVGQIELVDLSLIESRIDEIYEAMKKMKEEGGYAGIFLMLTDIMKEGTELLVVTDYPEVVEKAFGKKLEGKSVWLDGVMSRKKQVVPPLEKAFAEL
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_HYDCU
Sequence: MTKPTSTADKSLLGQTTPYCQAYDPTILFPIPRQEKRDELGFDLKTLPFTGEDVWTGYEISWLNLKGKPQVGWAEFVFSAEAPNLIESKSFKLYLNSFNGTRFESEDAVIACWQNDLSQACGKPVGVRFYRLDESIVLQGNLPGHCLDALDIEVEDYQVNPDLLHTDSDQIVSETLNSHLLKSNCLVTGQPDWGSIVVRYEGAQINHEALLKYLISFREHNEFHEQCVERVFTDIMRFCQPKKLTVYARYLRRGGLDINPYRSNYEQVFDRARLVRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPA_PSEE4
Sequence: MDFKDYYKILGVEASADEKAIKAAYRKLARKYHPDVSKERDAEDKFKEANEAYEVLGDKDKRAEYDEIRKYGGQHGRPFQAPPGWQSRGGNGGGGGFEGGDFSDFFSSIFGARGGNPFGGGGGRQQRSAGRRGQDVELELAVFLEETLNKESKQISFQVPQTNGAGQRTGFTTKTLNVKIPAGVTDGERIRLKGQGAPGVGGGANGDLFLTIRMAPHPLFDVEGHDLIITVPLAPWEAALGAKVAVPTLTGKINLTIRPDSQSGQRLRVKGMGLLNKQGERGDLYAQLKVVMPAQSDAAARELWTQLSEKAAFNPRTQWSK
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LAMP1_CRIGR
Sequence: MAAPGAPRSLLLLLLAGLAHGASALFVVKDSNGTACIMANFSASFFTIYETGHGSKNSTFELPSSAEVLNSNSSCGRENVSEPILTIAFGSGYLLTLNFTRNATRYSVQDMYFAYNLSDTQHFLNASNKGIHSVDSSTDIKADINKTYRCLSAIQVHMGNVTVTLSDATIQAYLLNSNFSKEETRCTQDGPSPTTVPPSPSPPLVPTNPTVIKYNVTGENGTCLLASMALQMNITYMKKDNMTVTRALNISPNDTASGSCSPHVVTLTVESKNSILDLKFGMNGSSSLFFLQEVRLNMTLPDANVSSLMASNQSLRALQATVGNSYKCNTEEHIFVTKEFSLNVFSVQVQAFKVESDRFGSVEECMQDGNNMLIPIAVGGALAGLVLIVLIAYLIGRKRSHAGYQTI
What is the function of this protein?
Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, autophagy, and cholesterol homeostasis (By similarity).  Also plays an important role in NK-cells cytotoxicity.  Mechanistically, participates in cytotoxic granule movement to the cell surface and perforin trafficking to the lytic granule.  In addition, protects NK-cells from degranulation-associated damage induced by their own cytotoxic granule content.  Presents carbohydrate ligands to selectins.  Also implicated in tumor cell metastasis (By similarity).
What are the official names of this protein?
Lysosome-associated membrane glycoprotein 1, LAMP-1, Lysosome-associated membrane protein 1, CD107 antigen-like family member A, Lysosomal membrane glycoprotein A, LGP-A.
What is the protein family that this protein belongs to?
Belongs to the LAMP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Cytolytic granule membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane (By similarity). Colocalizes with OSBPL1A at the late endosome (By similarity).
Protein: CK087_RAT
Sequence: MSARAPKELRLALPPCLLNRTFASHNASGGSNAGIRSSGAGGGTCITQVGQQLFQSFSSTLVLIVLVTLIFCLIVLSLSTFHIHKRRMKKRKMQRAQEEYERDHCSGSHGGGGLPRAGVQAPTHGKETRLERQPRDSAFCTPSNATSSSSSSPGLLCQGPCAPPPPPPVPSPHGAHAASSCLDTPGEGLLQTVVLS
What are the official names of this protein?
Uncharacterized protein C11orf87 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.