PharMolix/UniProtQA huggingface dataset:
Protein: E3B14_ADE07
Sequence: MQAMLPVILILLLPCIALASTATRATPEQLRKCKFQQPWSFLDCYHEKSDFPTYWIVIVGIINILSCTFFSITIYPTFNFGWNSPNALGYPQEPDEHIPLQHIQQPLALVEYENEPQPSLPPAISYFNLTGGDD
What is the function of this protein?
Down-regulates the EGF receptor and prevents cytolysis by TNF.
What are the official names of this protein?
Early E3B 14.9 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3_14 family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: SPN3_SCHPO
Sequence: MWYTYNEDFGVVQLLFLHSNDTLTARTHITKGQIDIELTMRTTKKSSKKGIPLNLMVVGDVGLGRTAFINTLCEKPLIRHNNNFDPAEASSVSPVEIVPYQTDIILEDGTKINLTVLDTPHFGEAIDNENNFDIILQYIESQYDNVLEEESRIKRNARFCDDRVHALIYFISPTGHGLRELDIELMRRLAPRVNIIPAIAKADSLTAQELQTTKEMINADIEYYKIPVYDFPYDIEEDEEAIINLSQQLRATIPFAIVSSDRLIEMNGQTVRGRAYPWGVVEVDNPRHSDFLALRSALFATHIEDLHNITSNQLYETYRTEKLSTSQLLLDSTVGLDGKNLSQHDQVLREDRLRAIELSVQKEIEEKRRQLLAREEALRALEEKLAASTAAMANASVSTLPSSVSSTNHSQS
What is the function of this protein?
Plays a role in the cell cycle.  Involved in a late stage of septum formation leading to the separation of the daughter cells.
What are the official names of this protein?
Septin homolog spn3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Localizes to the medial ring at the cell cortex of dividing cells.
Protein: NNRD_PHANO
Sequence: MASATRKDLLKKVYNMVPPMLESFHKGQLGRVAVIGGSEDYTGAPYFSAMASAKLGCDMSHVICEPGAGAVIKTYSPNLMVHPYMRQSKNVGQNENIESIKSEVVAMLSRLHVVVIGPGLGRDKLMQDTCAEVIQEARKQGIPFVLDADGLYLAQTRPELVDGCTECILTPNVVEFGRLAKAKGVNVDEGDPSELCSKLAKAFGGVTIIQKGAKDYISNGSQTLISEGEGGLKRSGGQGDTLTGSLATLLAYRKAYHDKIWDHGTNMEPSETLALAAYGGSCITRECSKLAYKEKGRSLQAADLTEHVHTAFLNVIGEKEETPKL
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSIE_EDWI9
Sequence: MPGTERANRVATVLQWILNIGLMALAAILVIFLAKETFTLAGVLFDANQNASTYMLVEGIVIYFLYFEFIALIVKYFQSGYHFPLRYFIYIGITAIIRLIIVDHESPNDTLIYSFAILVLVIALYLANTDRLKRE
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y859_YERP3
Sequence: MSIENTLPTYPSLALALSQQAVALTPAEMHGLISGMLCGGSKDNGWQTLVHDLTNEGVAFPQALSLPLQQLHEATQEALENEGFMFQLLIPEGEDVTVFDRADALSGWVNHFLLGLGMLQPKLAQVKDEVGEAIDDLRNIAQLGYDEDEDQEELAQSLEEVVEYVRVAAILCHIEFTQQKPTAPEMHKPTLH
What are the official names of this protein?
UPF0149 protein YpsIP31758_0859.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: VM2I_SISMB
Sequence: EAGEECDCGSPENPCCDAATCKLRPGAQCADGLCCDQCRFMKKGTVCRVAKGDWNDDTCTGQSADCPRNGLYG
What is the function of this protein?
Inhibitor of ligand binding to the integrins alpha-IIb/beta-3 (ITGA2B/ITGB3).  Competition with fibrinogen for the RGD recognition sites on the alpha-IIb/beta-3 integrin results in the inhibition of platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen.
What are the official names of this protein?
Disintegrin barbourin, Platelet aggregation activation inhibitor.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ENOD2_MEDTR
Sequence: MKCQRIEDDFTLKFYVFLLINTCSSIPFLFITTRGMASMHSLAILLLGVVMLTTPVLAEYYKPPTYEPPIEKPPIYEPPPTEEPPPVYKPPIIHPPPNYKPPAHTPPIYHPPHEKPPPVYEPPYEKPPHEEPPREYQPPRENPSPEYEPPHHGKPPYENPPPEYKPPYEKPPPEYQPPHHEKPPPEYQPPHEKPPPEYTPPYEKPPPEYQPPHEKPPHESSPPEYQPPHEKPPHEHPPPEYQPPHEKPPHEHPPPEYQPPHEKPPHVHPPPEYQPPHEHPPPEYQPPHEKPPHVHPPPEYQPPYLKPPHEKSPYEPPPQEYQPPHEKPPQMKPPSEYQPPHEKPPHEHPPPEYQPPHVHPPPEHQPPHENPPHENPPPEYQPPHEKPPHYEHPPPENQPPHVHPPPEYKPPHEKPPHEHPPPEYQPPQENPPPEYKPPHEKPPHENTPPTHHPPHEKPPQEISLPEYQPPPPSTKYQPPHEKSPHENPPPEFAPPHKKLPPNYNPPRHEKPMPKYQPPHEKLPPVYKSPYVKTPPPQAYHPPPPIYHHPPFHPPPHVKPPVYETPLAKVPQMKKPTRYNTRPFGHYPPYKKNQ
What is the function of this protein?
Involved in early stages of root nodule development.
What are the official names of this protein?
Early nodule-specific protein 2, Early nodulin-75-like.
What is the protein family that this protein belongs to?
Belongs to the nodulin 75 family.
Protein: RL27_STAS1
Sequence: MLKLNLQFFSSKKGLGSTKNGRDSESKRLGAKRADGQYVTGGSILFRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RLMF_PHOPR
Sequence: MTQKKNKPTQKKKGLHPRNPHSQRYDFNALILSCPDLTPFVAENQFGDLSVDFSDPAAVKMLNKALLHHFYNVENWDIPPGYLCPPIPGRADYIHHIADLLAKSNEGVIPQGKHINGLDIGMGANCVYPIIGHRAYGWRFVGSDVDALSIKSAKFIVESNRSLAGGIKCRLQKKSDNIFTGIINANDIFDFTMCNPPFHASLEEATAGSERKVRNLSANAHKKGSNKKAELFAKSNTNKPVLNFGGQKAELWCPGGEDAFIQRMITESSDKPENCFWYSTLVSKKENLPALYKALKQVNAVDVRTIDMAQGQKVTRIVAWTFLSKGQQTQWREERWSA
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_STAAC
Sequence: MSRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFKQEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGKDLILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGKGIRYQGEYVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PHZE_PSEFL
Sequence: MSQAAARLMERILQPVPEPFALLYRPESSGPGLLNVLIGEMSQPQVLADIDLPAPSIGAPRLDVLTLIPYCQIAERGFAAVDDQSPLLAMNITEQQTISIEQMLALLPNVPIQLNNERFDLSDASYAEIVSQVIANEIGSGEGANFVIKRTFLAEISEYQPASALSFFRHLLEREKGVYWTFIIHTGSRTFVGASPERHISVKDGLAVMNPISGTYRYPPAGPSLTEVMDFLADRKEADELYMVVDEELKMMARICEDGGHVLGPYLKEMTHLAHTEYFIEGRTRRDVREILHETLFAPTVTGSPLESACRVIERYEPQGRAYYSGMAALIGSDGKGGRSLDSAILIRTADIDNCGQVRISVGSTIVRHSEPLTEAAESRAKAAGLIAALKNQAASRFGDHLQVRAALASRNAYVSDFWLMNSQQRQQTQSDFSGRQVLIVDAEDTFTSMIAKQLRALGLVVTVRSFSDEYSFDGYDLVIMGPGPGNPSDVQLPKIDHLHVAIRSLLNQQRPFLAVCLSHQVLSLCLGLELQRKAIPNQGVQKQIDLFGNAERVGFYNTFAARSSSDRLDIDGIGTVEISRDSETGEVHALRGPAFASMQFHAESLLTQEGPRIIADLLRHALIHTPVDSSVSAAGR
What is the function of this protein?
Involved in the biosynthesis of the antibiotic, phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control.
What are the official names of this protein?
Anthranilate synthase, phenazine specific.
Protein: ATPE_NOVAD
Sequence: MSLHFELVTPARLVRSEEVHMVVVPGTDGEFGVLEGHAPFMSTVKDGAIKVYRSAGAAPEEIQVQGGFAEVSAKGLTVLAEHVEG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RISB_SYNAS
Sequence: MPTVTEGRLIAKGMKFGIAVSRFNDFICSRLLDGALDALTRSGAEGKDIQVYRVPGAFELPLVAKKLAVSQRFEAVICLGAVIRGATPHFEYVSAEVSKGIANASLDTGVPIAFGVLTTDTIEQAIERAGTKAGNKGWDAAMTAIEMVDLLRQI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ASSY_BRUA1
Sequence: MSKWKDVKKVVLAYSGGLDTSIILKWLQTELGAEVVTFTADLGQGEELEPARKKAEMLGIKEIFIEDVREEFVRDFVFPMFRANAVYEGVYLLGTSIARPLISKHLIDIAKKTGADAIAHGATGKGNDQVRFELSAYALNPDIKIIAPWRDWSFKSRTQLLEFAEQHQIPVAKDKKGEAPFSVDANLLHSSSEGKVLEDPSQEAPEYVHMRTISPETAPDKATIIKIGFEKGDAVSINGERLSPATLLAKLNDYGRDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRAIESITLDRGAAHLKDELMPRYAELIYYGFWFSPEREMLQAAIDHSQRHVEGEVTLKLYKGNVMVIGRESAKSLYSDKLVTFEDDQGAYDQKDAAGFIKLNALRLRTLAARDRK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_ECOL5
Sequence: MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADVACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVNDVKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP4_CRYNJ
Sequence: MALGDKNQGSSKSQAKQKGTKGKNAQPRLKSNQLKRLKINEELKELQSRVDNFVPPSEITLFSELPMSSKTQKGLKSSHFLNPTPIQSLAIPPALQARDILGSAKTGSGKTLAFLIPLLERLYLEKWGPMDGLGAVVISPTRELAVQTFMQLRDIGKYHNFSAGLVIGGKPLKEEQERLGRMNILIATPGRLLQHLDSTVGFDSSAVKVLVLDEADRLLDLGFLPALKAIVSHFSPVQTAPGSRPSRQTLLFSATQSKDLAALAKLSLYEPLYISCNKPGEEGVMPANLEQYYAVVPLERKLDALWGFVKSHLKMKGIVFVTSGKQARRVRFIFETFRRLHPGLPLMHLHGKQKQPTRLDIFQRFSSSKSALLICTDVAARGLDFPAVDWVIQLDCPDDVDTYIHRVGRTARYQSAGTALTILCPSEEEGMKTRWGEKAIEVKRIKIKEGKMGNLKQSMQNFAFKEPEIKYLGQRAFISYMKSVHIQKDKSIFKIDALPAEAFAESMGLPGAPQIKLGNQKAAKVRGPSKEELARKAEKEEEEEEERAVVGSDEESEEDESEGLGSEDEEEEIDDEAEEIDDEEESGEESGSDEETEEEKDASKPKAPAVRTKYDRMFERKNQSILTPHYTALIAHDADNAAGAGEADDDDDVFTLARRDHNLSDDEEADTDAILGAEALAAELKKPLITSEDLSKRKLKAAASKKGLLKSRPGPEKVLFDEETGEAREFYKSGVDVEKEMSAADKRREYLEKEREIMKIQDKIDKEVAREKKKELKRKRKERERELRQMEMGDEPVAYLGGDDDYASADEGRSLSPSPAPSLEPERHAKKQRRGGVQESGAGDLEDEEALALRLLQGS
What is the function of this protein?
ATP-dependent RNA helicase required for ribosome biogenesis.  Involved in the release of U14 snoRNA in pre-ribosomal complexes.  Required for pre-rRNA cleavage at site A2 (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CYO13_VIOOD
Sequence: MDAKKMFVALVLIATFALPSLATFEKDFITPETIQAILKKSAPLSNIMLEEDVINALLKSKTVISNPIIEEAFLKNSNGLNGIPCGESCVWIPCISAAIGCSCKSKVCYRNSLDN
What is the function of this protein?
Probably participates in a plant defense mechanism.  Has hemolytic activity.
What are the official names of this protein?
Cycloviolacin-O13, Cyclotide c3.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: FSBP_HUMAN
Sequence: MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNRCWDIIAVNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETQSDFKSNISEPTKKVMEMIPQISSFCLVRDRNHIQSANLDEEAQAGTSSLQVMLDHHPVAITVEVKQEEDIKPPPPLVLNSQQSDTLEQREEHELVHVMERSLSPSLSSVDMRMTSSPSSIPRRDDFFRHESGEHFRSLLGYDPQILQMLKEEHQIILENQKNFGLYVQEKRDGLKRRQQLEEELLRAKIEVEKLKAIRLRHDLPEYNSL
What is the function of this protein?
Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain.  Represses transcription of GSK3B gene promoter via its interaction with APBA1.
What are the official names of this protein?
Fibrinogen silencer-binding protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS6_HAEI8
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAQRYAQEGADELVFYDITASSDGRTVDKSWVERIAQVIDIPFCVAGGIKTIEDAEKLFAFGADKISINSPALADPTLISRLADRFGVQAIVVGIDSWFEQETGKYWVNQYTGDETRTRQTHWQLLDWVKEVQQCGAGEIVLNMMNQDGLRNGYDLAQLKLVRGVCRVPLIASGGAGKMVHFRDAFIEAKVDGALAASVFHKQIIEIGELKSYLVQSAIEIRSE
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP183_RAT
Sequence: MANNFTTPLAASHGNNCDLYAHHSTARILMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSMNLVISDILFTTALPTRIVYYALGFDWRIGDALCRITALLFYINTYAGVNFMTCLSIDRFFAVVHPLRYNKIKRIEYAKGICVFVWILVFAQTLPLLLKPMSKQEADKTTCMEYPNFEGTASLPWILLGACLLGYVLPLAIILLCYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIGVFVLCFTPYHVAIMQHMVKTLYAPGALGCGVRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMKMLKRQVSVSISSAVRSAPEENSREMTESQMMIHSKASNGR
What is the function of this protein?
G-protein coupled receptor expressed in lymphocytes that acts as a chemotactic receptor for B-cells, T-cells, splenic dendritic cells, monocytes/macrophages and astrocytes (By similarity).  Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols (By similarity).  Mediates cell positioning and movement of a number of cells by binding the 7-alpha,25-OHC ligand that forms a chemotactic gradient (By similarity).  Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses (By similarity).  Guides B-cell movement along the B-cell zone-T-cell zone boundary and later to interfollicular and outer follicular regions (By similarity).  Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity).  Collaborates with CXCR5 to mediate B-cell migration; probably by forming a heterodimer with CXCR5 that affects the interaction between of CXCL13 and CXCR5 (By similarity).  Also acts as a chemotactic receptor for some T-cells upon binding to 7-alpha,25-OHC ligand (By similarity).  Promotes follicular helper T (Tfh) cells differentiation by positioning activated T-cells at the follicle-T-zone interface, promoting contact of newly activated CD4 T-cells with activated dendritic cells and exposing them to Tfh-cell-promoting inducible costimulator (ICOS) ligand (By similarity).  Expression in splenic dendritic cells is required for their homeostasis, localization and ability to induce B- and T-cell responses: GPR183 acts as a chemotactic receptor in dendritic cells that mediates the accumulation of CD4(+) dendritic cells in bridging channels (By similarity).  Regulates migration of astrocytes and is involved in communication between astrocytes and macrophages (By similarity).  Promotes osteoclast precursor migration to bone surfaces (By similarity).  Signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha (By similarity).  Signals constitutively also via MAPK1/3 (ERK1/2) (By similarity).
What are the official names of this protein?
G-protein coupled receptor 183, Epstein-Barr virus-induced G-protein coupled receptor 2, EBI2, EBV-induced G-protein coupled receptor 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL14_ECOL5
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKPVVVRTNKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HPT_CAPIB
Sequence: MSALQAVVTLLLCGQLLAVETGSEAAAGSCPKAPEIANGHVEYSVRYQCDKYYKLRAGNGVYTFNNKQWINKDIGLQLPECEEDVSCPEPPKIKNGYVEYSVRYQCKTYYKLRTCGDGVYTFNSKKQWINKNVGQQLPECEAVCGKPKHPVDQTQRIIGGSLDAKGSLPWQAKMVSHHNLISGATLINERWLLTTAKNLYLGHTSDKKAKDITPTLRLYVGKNQLVEVEKVVLHPDHSKVDIGLIKLREKVPVNDKVMPICLPSKDYVAVDRVGYVSGWGRNENFNFTGHLKYVMLPVADQDKCVKHYEGNNAPKNKTATSPVGVQPILNENTFCVGLSKYQEDTCYGDAGSAFVVHDQEDDTWYAAGILSFDKSCAVAEYGVYVKVTSILDWVRKTIANN
What is the function of this protein?
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine.  Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage.  Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response.  Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity).
What are the official names of this protein?
Haptoglobin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ZDHC4_ARATH
Sequence: MGRKKSCHVHNAPSDDDIMFSQDHKPKRIYQLWPGNNRFYCGGRLVFGPDASSLLLTTAMIGGPALTFCIRMVFLIGKRYPLFHSLILLGALLLTVLDFTFLFLTSSRDPGIIPRNKEAPEAEGLDMITQSSEWVNNKLGNTKIPRTKDILVNGYTVKVKFCDTCLLYRPPRASHCSICNNCVQRFDHHCPWVGQCIALRNYPYFICFISTSTLLCLYVFVFSWVSMLEVHGKMLLMVITNDLVFVVLILYCFVVVWFVGGLTVFHLYLICTNQTTYENFRYRYDKKENPYGKGLFKNLYELFFARIPPPMINFRDWAPEEPDEEVGSIASELDRTFGPRGDKYDMEMEIGGCKNSKVGLQLHTLEYDNNNSSEETVKKKGVSEETAAFYIPGIQEPANITRNSSIDVRSR
What is the function of this protein?
Palmitoyl acyltransferase.
What are the official names of this protein?
Probable protein S-acyltransferase 2, Probable palmitoyltransferase At2g40990, Zinc finger DHHC domain-containing protein At2g40990.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: YQGF_BRASB
Sequence: MPAPILPLIEAASRWPERGALVGLDLGTKTIGVAVSDPDRRLATGVETIQRKAFKADAARLLAISSERKVVGFVLGLPINMDGSEGPRAQSTRAFARNLANLTDLPIGLWDERLSTAAVERELIGMDVSRARRAEVIDTHAAIFILQGALDRLATLRRSGQ
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA2_CLOPE
Sequence: MRNIKLTIEYDGTSYFGWQKQPIGNTIQQKVEEAIKKVTKEEVEILGSSRTDSGVHAKAYVANFKTNSNIPGKNFKAALNSKLPKDIVIINSEEVAEDFHARYMTTGKTYCYTILNREEPPALERNYVYHVKKQLDVESMKEACKYFLGKHDFKAFQRPGGTVKTSVRTITDIHIETEGNKIKIYVSADGFLYNMVRLIVGTLLKVGRGKEKPEYIKEVIDSGDRKKAGICVPPTGLCLEKVFY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A 2, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I 2, tRNA-uridine isomerase I 2.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MDTD_ECOSE
Sequence: MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSKGTGLSPLTIDGLVAVGVVALVLYLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSIDSGTTQTVFMYTWLSMALIIALPAFIFARVPNDTHQNVAISRRKRSAQ
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CELF3_BOVIN
Sequence: MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQVATQLGMFSPIALQFGAYSAYTQALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAINANGLIATPITPSSGTSTPPAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYPAQSPAAPVDPLQQAYAGMQHYTAYPAAYSLVAPAFPQPPALVAQQPPPPPQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY
What is the function of this protein?
RNA-binding protein involved in the regulation of pre-mRNA alternative splicing.  Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing.  Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition.  Activates the splicing of MAPT/Tau exon 10.  Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA (By similarity).
What are the official names of this protein?
CUGBP Elav-like family member 3, CELF-3, Bruno-like protein 1, CUG-BP- and ETR-3-like factor 3, ELAV-type RNA-binding protein 1, ETR-1, RNA-binding protein BRUNOL-1, Trinucleotide repeat-containing gene 4 protein.
What is the protein family that this protein belongs to?
Belongs to the CELF/BRUNOL family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CALB2_BOVIN
Sequence: MAGPQQQPPYLHLAELTATQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMVSKSDNLGEKMKEFMQKYDKNSDGKIEMAELAQILPTEENFLLCFRQHVGSSTEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENELDALLKDLYEKNKKEMNIQQLTSYRKSVMSLAEAEKLYRKDLEIVLCSEPPL
What is the function of this protein?
Calretinin is a calcium-binding protein which is abundant in auditory neurons.
What are the official names of this protein?
Calretinin, CR.
What is the protein family that this protein belongs to?
Belongs to the calbindin family.