PharMolix/UniProtQA huggingface dataset:
Protein: 6PGL_YERPB
Sequence: MKQAVYVASPDSQQIHVWQLDSAGELTLLQTVDVPGQVQPMAISPNQRHLYVGVRPDFGIVSYHIADDGTLTAAGMAPLPGSPTHIDTDRQGRFLFSASYSFNCVSISPIDTHGVVQAPIQQLDDLPAPHSANIDPTNQILLVPCLKEDKVRLFDLSAEGQLTPHAQADITVAAGAGPRHMAFHPNHQVAYCVNELNSSVDVYQISNNGQEYHLVQSLDAMPADFTGTRWAADIHITPNGRYLYISDRTANLLGIFTVSKDGRVISLVGHHLTEAQPRGFNIDHSGNFLIASGQKSDHIEVYRIDQNTGELTTLKRYPVGKGPMWVSIRGAQNS
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: TRPD_CHESB
Sequence: MADLKAHIAKVASGAALSFAEAREAFGIIMSGEATPSQIGGFLMALRVRGETVDEISGAVDTMRSKMLPVTAPAEAVDIVGTGGDASGTYNVSTCAAFIVAGCGVPVAKHGNRALSSKSGAADSLVALGVNIELGPDQIAACIAEAGVGFMFAPSHHAAMRHVGPTRVELGTRTIFNLLGPLSNPAGVKRQLVGVFSAQWVEPLAHVLRQLGTEKAWVVHGDGLDEMTTAGVTRVASLEYGEVRTFEITPEEVGLQRSAAAALKGGDGEYNGKALRRVLEGERNAYRDIAVLNAGGALIVAGKAETLKDAVALASESIESGRALAALEKLVEVSNRKP
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: NU5C_PLAOC
Sequence: MEHTYQYAWIIPFLPLPVPMLIGVGLLLVPRATKNLRRMWAFPSVLLLSIVMIFSADLSIQQLNGSSIYQYVWSWTINNDFSLEFGYLIDPLTSIMSILITTVGIMVLVYSDNYMSHDQGYLRFFAYMSFSNTSMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPIAANACQKAFVTNRVGDFGLLLGILGLYWITGSFEFRDLFEIFNNLIYNNRVNSLFVTLCASLLFVGAVAKSAQFPLHIWLPDAMEGPTPISALIHAATMVAAGIFLVARLFPLFTVIPYIMNLISLIGIITVLLGATLALAQKDIKRSLAYSTMSQLGYTMLALGMGSYRAALFHLITHAYSKALLFLGSGSIIHSMETVVGYSPEKSQNMALMGGLTKYAPITKTAFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIACSTAGLTAFYMFRMYLLTFEGHLNVHFQNYSGKKNSSFYSISIWGKKETKTINIRKYFCLSTLSTMNDNEKDSYFLKKGYPIHGNVRSMARPLITISHFGNKETFPYPHESDNTMLLPLLVLVLFTLFVGFIGIPFDQEGMDLDILSKWLAPSINLLHPNLSNSVDWYEFITNAIFSVSIAYFGIFIASLLYRPVYSSFQNLELINFFVKMGPNRILWDQLLNIIYNWSYNRGYIDFFYAKTFIRGIRGLAELTHFFDRRVIDGITNGVGVTSFFVGEGIKYVGGGRISSYLFLYLSYVLIFLLISYFLFLNL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YIGZ_ECOLI
Sequence: MESWLIPAAPVTVVEEIKKSRFITMLAHTDGVEAAKAFVESVRAEHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRYYGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYHQLTGIEALLGQCDGKIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE
What are the official names of this protein?
IMPACT family member YigZ.
What is the protein family that this protein belongs to?
Belongs to the IMPACT family.
Protein: LEU3_HELHP
Sequence: MQKRIAVIYGDGIGKEVITQALKILKAVAKKYEHTFIFEEVLAGGAAIDECGECLPMKSLQICKQSDSVLLGAVGGPKWDNEPSHNRPEKALLTLRKELGLFANIRPATLLPQLSKASPLKDEILNRGIDFIIVRELIGGVYFGEHKLEEINGEKVASDAMTYSASQIESIAKVAFNIARNRKKEIVCVDKANVLSSSRLWREVVDKVAQNYKDVHLSYMYVDNAAMQICRAPSQFDVILTENMFGDILSDEASIITGTIGVIPSASLSNGTLGMYEPIHGSAPDIAGQDKANPIGTILSAAMMLELSFGLTKESEVIQKAVQNALDKGYRTGDMMSEGMQLVGCEQMGDVILESVI
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMC_XYLFT
Sequence: MPSPIALLAAATERIERVDAEALLLHALDCDRAWLFTHGDIPLAAAATESFQALVEQRARGIPVAYLIGRRGFWTLDVIVSSATLIPRAETETLVEQALQRLDHASERRVADLGTGSGAIALAIACERPQAQVLATDNSAAALDIAARNASAHGLNHVVFREGNWYEALLGERFDLIVSNPPYIAVTDPHLTQGDLRFEPPSALISGGDGLDALRILAAGAPAHLRPGGWLVLEHGWDQGAAVRTLLHTAGLVAVATMQDLEARDRVTVGRCPGF
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, M.XfaHemK2P, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: HIS1_STRAW
Sequence: MLRIAVPNKGSLSGPAAEMLHEAGYQQRRESKELRIVDPENEVEFFYLRPRDIAIYVSSGRLDIGLTGRDLLIDSGANAEEILPLGFARSTFRFAGKPGTAKGIEDLAGLTVATSYEGIVAKHLADSGIDASVVHLDGAVETAIELGVAEVIADVVETGTSLRNAGLEVFGEPIMKSEAVVIRRVGAGTDEAAESKVQQFLRRLQGVLVARTYVMMDYDCRAEHLEKAVALTPGLESPTISPLHNEGWVAVRAMVPAKEAQRIMDDLYALGARAILTTAIHACRL
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_PROMH
Sequence: MKKVLLTVCAIALFGSQAAWADARQDLQQRLNKVNSFQANFSQTVTSNEGALIQKGEGHLKVQRPDLFNWQMTAPDESTLISDGKTLWFYNPFVEQVTATWLESATTNTPFMLIARNDSKEWQNYDVKQNGDRFELTPKTENNLKHFSITVSPNGQIQQFAATEQDGQVSQYQLTAQKVAPIDASAFRFTPPAGVTVDDQR
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSIE_SALA4
Sequence: MMPLSRSRLEFIATILQNVLNLGLLTLGLILVVFLGKETVHLADALFVPEQASKYELVEGLVIYFLYFEFIALIVKYFKSGLHFPLRYFVYIGITAIVRLIIVDHKTPMDVLLYSAAILLLVITLWLCNSNRLRRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHSC_IPOPU
Sequence: MSTAVTILTDTWTRREKRFDGHAKILAIGTAIPANWVDQTTYPDFYFRITNSEHLLEYKEKFRRICNKSKIRKRHLVITEELLKKNPNLCTYNDASLNTRQDILVSEVPKLGKEAAMKAIKEWGRPISEITHLVFCTSSGVDMPGADFQLAKLLGLSSSVNRLMMYQQGCNAGAVMLRLAKDLAENNKGGRVLVVCSEVMLSVFRGPSLQQEDNLLAQCLFGDGSAAVIVGTEPRPGLETPLFELVSAAQTTIPDTDSYLKLQLREMGLTFHCSKAVPSLITQNIEDCLVKAFEPFGISDWNSIFWILHPGGNAILDGVEEKLGLEPEKLRASRDVLSQYGNLTSACVLFKP
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase C, Naringenin-chalcone synthase C, CHS-C.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: CAER_PHYSA
Sequence: QEYTGWMDF
What is the function of this protein?
Hypotensive neuropeptide.
What are the official names of this protein?
Phyllocaerulein.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FB56_ARATH
Sequence: MEKLKQQFSKDRLITPSSNLVRNYIDSIPVDLLIDILSRFPPKSIARFYCVSKLWESILRGPDFTELYLTKSVALRRLFFALKVNTELLVFSSPQPQIPDENSSLVVEATPYKCFPKKIPTEICTALGGLVFLGTFLSRQPLVIVNPLTGEFITLPKLKTIGTKRFSFGYDPISKKFKVLCVTWSPCGTLPNIHQVLTLETGERLWRTIHDPVIPRYSINYDAICINGVLYSEAYYQGSSKIVCFDFKIEKVSFVNIDGMCNLRLFNCKGKLGVHQYDVQSRNEKLVFHVLEDAEKHKWSKSICILPSVVSGKRIVEITCTGEIVFSPSGGSLHPFYIFFYNIERKTYTRVQIKGFKKYADCVHTFLDFVEDTKLI
What are the official names of this protein?
Putative F-box protein At1g53370.
Protein: DTD_NEIMB
Sequence: MRAVIQKTVGAKVDVVSEAGTETCGKIDGGFVVLLGVTHSDTEKDARYIADKIAHLRVFEDEAGKLNLSLKDVGGAVLLVSQFTLYADAASGRRPSFSQAAPAEQAQQLYLRTAELLRGHGIHVETGRFRTHMQVSLCNDGPVTILLDSFMTRISPKMKVVPD
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYGO1_HUMAN
Sequence: MPAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA
What is the function of this protein?
Involved in signal transduction through the Wnt pathway.
What are the official names of this protein?
Pygopus homolog 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPA_ERWT9
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYADLAEGMTVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGAIDNDGFSPIEVIAPGVIDRQSVDQPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTAMAIDAIINQRDSGIKCVYVAIGQKASTIANVVRKLEEHNALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAFPGDVFYLHSRLLERASRVSADYVERFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNSGIRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFSQFASDLDEATRKQLSHGQKVTELLKQKQYAPMSVAQQGLVLFAAERGFLNDVELAKIGSFEAALLAYADRDHAELMADINQSGNYNGEIEEKLKGLLETFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KEFC_SALCH
Sequence: MDSHTLLQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFVIGLELDPQRLWKLRASVFGGGALQMVVCGGLIGLFCMFLGLRWQVAELIGMTLALSSTAIAMQAMNERNLTVSQVGRSAFAVLLFQDIAAIPLVAMIPLLAASGASTTLGAFALSALKVAGALALVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLVENPLRILLLLAGFLAIKIVMLWLVARPLGVPAKQRRWFAVLLGQGSKFAFVVFGAAQMADVLEPEWAKALTLAVALSMAATPIFLVLLTRMEKTATGEAREADEIDEEQPRVIVAGFGRFGQIAGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLSELVKSHFPHLQIIARARDVDHYIRLRQAGVAMPERETFEGALKSGRQALEALGLGRYEARERADLFRHFNTRMVEEMAKGENDPLSRAAAYKRTSAMLSEIITEDREHLSLIQRHGWQGTAEGKHSGEAADEPEVKPSI
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLSA_ECO24
Sequence: MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAPLFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIYSCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQDDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU2M_FORLA
Sequence: MNPYVLMILISSLGLGTTLTFASSHWLLAWMGLEINTLAILRLMAQQHHPRAVEATTKYFLTQATAAAMILFAATTNAWATGEWDINNLTHPLASSLTMMALALKVGLAPMHFWMPEVLQGLDLTMGLILSTWQKLAPFALITQMAPNTNPMLLTTLGLLSTLIGGWGGLNQTQLRKILAYSSIAHMGWMIIILQYTPQLTLIALGLYIFMTSAAFLSLKMASATKMNTLTAAWSKSPVLVSTTALTLLSLGGLPPLTGFMPKWLILQELTKQDLPATATIMALAALLSLYFYLRLSYAMALTIYPNTTNALTPWRTNTTQSTLALALMMIGALGLLPLTPTIMALFF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NDHI_ILLOL
Sequence: MFPMLNGFMNYGQQTVRAARYIGQSFMITLSHTNRLPVTIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWRLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQISLGRLPMSVIGDYTIQTIMNSTQMKIAMDKSLDSRTITNY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ATG7_PICAN
Sequence: MEPKYINTQSFVDSSFFVKLSQLKLDVLKLDQSSRPIHGYYNYKRLAPGQAPAINLNDISFASGQELESQLPARSAFIVSGEITNVNTLEEFKSQSKLEFLTRAGGKIIDSIKNKAALQDPSLLAHFAVFSFADLKKYKFYYWFAFPTLHSEWHITSEGPLGGDAPDSQFSLIRDGKPVPLAQLNAVPTHSPLHVAFVDTSAVPDAYSYVLRNFLTMLAIYGYRDVVVDVHRDNQSSSRQIALKLQSAVDSPKISGWERTSQGKLGPKLADLGALIDPSQLADQAIDLNLKLMKWRIVPTLDLDRIKATKCLLLGSGTLGSYVGRALLAWGVRKITFVDNGKVSFSNPVRQPLFNFIDCLDGGSPKAETAAENMKRIFPLVDAQGFTLEVPMAGHPITDETKQKLDFDRLGELVQNHDVIFLLMDSRETRWLPTVMGNVNNKLVINAALGFESYLVMRHGCINPEKLPEEQQESRLGCYFCNDVYAPSDSTTDRTLDQMCTVTRPGVALMAASLAVELMVSVLQHPDRQYAPHSAQDSCTVLGSLPHQLRGFLHNFEMLKLSAKNFRYCSACSVSVVQEFKSRGWEFVKQALENPKYLEQLTGLTQVHQQAEEAELNFDISDSEGEFD
What is the function of this protein?
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy.  Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine.  Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Plays a role in the regulation of filamentous growth and chronological longevity (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, Autophagy-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the ATG7 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: TATA_CHRSD
Sequence: MLGGISIWQLLIVLGIVILIFGTKKLRNLGSDLGGAVKGFKSAVGEEEQKKQDGEETAQHRVAHDTNEEPLDTSSKATQSSGADEKSERK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HIS6_YERPE
Sequence: MLAKRIIPCLDVKDGQVVKGVQFRNHEIIGDIVPLAQRYAQEGADELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIKSVEDASQILTFGADKISINSPALADPTLITRLADRYGVQCIVVGIDTWYDTESDSYQVYQFTGDEKRTKATTWQTEDWVKEVQLRGAGEIVLNMMNQDGVRNGYDLRQLQQMRAICHVPLIASGGAGTPDHFLEAFRDADVDGALAASVFHKQIINIGELKKYLSEQGVEIRVC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC2_BACCZ
Sequence: MRYITAGESHGPQLTVILEGVPAGLTLTAEHINKELLRRQKGHGRGRRMQIETDTVEIVSGVRHGMTLGSPITLIVKNDDFKHWTKVMGAEPISEKESKEMKRTITKPRPGHADLNGAIKYGHRDIRNVLERSSARETTVRVAAGAVAKQILKELGVEIAGHVLEIGGVEAKHISNLSIEEIQTITENSPVRCLDKTVEQEMMDAIDNAKSSGDSIGGIVEVIAEGMPIGVGSYVHYDRKLDAKLAGAIMSINAFKGAEIGVGFEAARQPGSKVHDEILWDEEQGYTRKTNNAGGLEGGMTTGMPIVVRGVMKPIPTLYKPLASVDIDTKEAFQASIERSDSCAVPAAGVVAESVVAWELAHALVEQFGKDRMELIQQNITQHNKYAKEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase 2, CS 2, 5-enolpyruvylshikimate-3-phosphate phospholyase 2.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RPOB_SALTI
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVVSKDYVDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIEEGNYVIAQANSNLDDEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSFLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ACCA_SHIDS
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_ANAD2
Sequence: MTDLPFVTADLPGSGGALRRAPEDFRVDEVPAYLPSGAGPHLYLRVEKRGRTSRDAVRELARALGVPERDAGCAGLKDKDAVTTQWLSFPVARDPDPAALAAPGLRVLEASRHQNKLRTGHVRANRFTLAVRGGDLGRARECAGALAARGLPNFFGPQRFGAAGRNAAVGRALVTGERTPEAGRAARDRFLRRLSLSAYQSLLFNRWLAERMADGLFAAALAGDAMKKLDTGGLFTCEDPAADGPRVERFEISPAGPMFGHALRLAAGEAGAREARLLEAEGIALADFARGGGEAEGTRRAARLRVEVALEPLEDGYRAAFELPRGAYATVVMRELTKGEAELPEDAD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.