PharMolix/UniProtQA huggingface dataset:
Protein: COX8A_PANTR
Sequence: MSVLTPLLLRGLTGSARRLPVPRAKIHSLPPEEKLGIMELAVGLTSCFVTFLLPAGWILSHLETYRRPE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8A, mitochondrial, Cytochrome c oxidase polypeptide VIII-liver/heart, Cytochrome c oxidase subunit 8-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: EXOC1_DROME
Sequence: MLSIGAMANIKHTLQKELFLASGERLLSVVTVVKKKDKKPCYLCVVTTAPPVPVVTLCLIKQSEQREGEYKRKRSWQLDEIKWVDGRNEQFETHEFDLQLEKLYKWYALNPHERQNFLAVLNRQIQKSVRGQRAEFRNVPAAWLSEKSPEKVALGRAVQKTQHMDDEEDEEEEAQEFTALTDKEANELGKLFSECDFAIKDAEQFIEQLSRELHDLDGANMQSVLASEQKVLKMMEHIDNAISEADKFENRLDSYEDILGHVKETMEKIGGKNAMIEIANNNNIKLMKELNKVISQLDLPHSQQQALDEPDLKTANGRKAAIAAAQCLQQAMNSDIDPALLRLEAVQDQRKRFEKWKQKFSATVSRFMNNLFIHLGNEIGDMQVTSTELTLPNHSNVHRELTPYTELMHWTKAMDRKTYDGLMRVYTASLSKIYDRDVRNFFNLAKIQVTEKLRNSREDLDMSTSSRKSAVSTIPYGTLGINRDQWGPGVETADRMRFDALLEKVLAELEPIALQEQLFCINFFQMDVISPTTKNTQTTLEMEKAVDMTQSIISGAVSPSGDGVPQKRIDRQINEDVRKLMMGLFGCLEPELVSFIQSFERVDSFYSLYVFVRLTQHVMSAQDTHSFLSMTFASALVQVKRSFDRFMQNQLLSIREAKLHKRSKAILPYVENFENFAQTAEGIFRKSDRRTDMEKWYLQLVNAIFEGIQLHSQEHPKTPVQVVRMENYHHMYALLAQLKVPGLDALKKEAKKCYNDALKAYVTQYFGRPLEKLNQFFEGVQLKVAQGVKETEISYQMAFSKQELRKVIAQYPAREVKKGLENLYKKVEKHLSEEENLLQVVWHAMQEEFIAQYNYLEERIQKCYAGAMINLEFNIQDILAFFSDIARSH
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component 1, Exocyst complex component Sec3.
What is the protein family that this protein belongs to?
Belongs to the SEC3 family.
Protein: SYGB_PSYIN
Sequence: MAQENLLIELGTEELPPKSLRQLAESFASNVEAELNKAELSFDSVRWLASPRRLALVIANLSDSQADKIVEKRGPAVNVAFDAEGQATKAAQGWARSNGITVEQAERLITDKGEWLLFKSEVKGLSVAELIPEIAANALAKLPISKPMRWGSSSTQFIRPVHTVTMLFGSRLIQGELLGVASDRIIRGHRFLGEAELIIDHADQYETLLDDSGKVIVDYERRKAIIRDQVEALAAHENGVADIDESLLEEVTSLVEWPVTLVGSFEDKFLDVPSEALIYTMKDNQKYFPVLDKDGKLLPRFIFVSNIVSRDPAQVISGNEKVIRPRLADAEFFFETDKKKTLASRLESLSSVLFQQKLGTLKEKSERIANVAEDIALQIKADTKHAQRAGLLSKTDLMTDMVMEFPDVQGIMGMHYALHDGEEQEVAIALNEQYLPRFAGDKLPTSLVACAVSLADKLDTLVGIFGIGQAPKGAADPFALRRAAIGLLRIITNKNLDLDLVELVEIAKLQYGHKLTNDNVVQDVVDFLFARFRATYQANGYSVELIQSVLVRRPTKPVDFEKRLQAVAKFQTLPEAAPIAAANKRISNILAKVKGEINAQVDPSLLQEPAEIKLSEILGSLESTLRPLFDNLDYESALFELASLNEPVDEFFDNVMVMAEDPAIKANRLAILNRLRNLFLQIADVSVL
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_HISS2
Sequence: MAKLHDYYRDTVVNELKAKFNYSSVMQVPRIEKITLNMGVGEALTDKKLLDNAVADLAAISGQKPLVTKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLNTKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGQALLAAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: COQ4_ASPFN
Sequence: MSVLRRRGALSLRELSLSTPVTVVSCRARSFSVNNRPPPKYPGHVPLNFVERGALAVGSAVGALLNPRRADLIAACGEATATPYFIYRLRDAMLSDPTGRQILRERPRITSETLPLPYLRSLPENSVGRTYAAWLDREGVSPDTRDNVQYIDDEECAYVMQRYRECHDFYHAVTGLPTFVEGEIALKAFEFLNTLIPMTGLSMFAAVRLKPAERERFFALWLPWAVRSGLASKELINVYWEKILEKDVDELRGELGIEKPPDMREIRRMIREQKKREKERLQQSA
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein coq4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y2258_MYCTU
Sequence: MSGALETTEEFGNRFVAAIDSAGLAILVSVGHQTGLLDTMAGLPPATSMEIAEAAGLEERYVREWLGGMTTGQIVEYDAGSSTYSLPAHRAGMLTRAAGPDNLAVIAQFVSLLGEVEQKVIRCFREGGGVPYSEYPRFHKLMAEMSGMVFDAALIDVVLPLVDGLPDRLRSGADVADFGCGSGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFERHDLAELDKVGAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKASSQLEDNVGVPLSTYLYTTSLMHCMTVSLALDGAGLGTVWGRQLATSMLADAGFTDVTVAEIESDVLNNYYIARK
What is the function of this protein?
Probable methyltransferase that may target bulky nonpolar molecules with aromatic rings.
What are the official names of this protein?
S-adenosylmethionine-dependent methyltransferase Rv2258c.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily.
Protein: PCL10_YEAST
Sequence: MDMTKNHTTDTEEFDDGDIRPVSLGIVDDYNASFELPLKPKFLQSENFSDLTSEWDQSRSNTPGLAEGKTEKAQPCGTTDSSKNRIHVEQLLESANEMNNYLAQNIENINNFQVGLLNGGKGLYSSMGDDSSACINGTNFSSTSNFELSDDELEDTTGCTSSIFDKDLFHQQNGLSIPRRRSPLFKSPTASFEIGDATDVEEQDIDDSIFSECSSITSFDMGGLHISLPHDEEEDQEKTKSESENPLLHGIPVDVEVPHISVDEALANFKETIELLLKLSGNRKCTGFNTRVEKKEYSNFYMKSKPTLSSADFLKRIQDKCEYQPTVYLVATFLIDTLFLTRDGNNILQLKLNLQEKEVHRMIIAAVRLSTKLLEDFVHSHEYFSKVCGISKRLLTKLEVSLLICVCNTKLMVSNRKLAASKLLLNELRSFCV
What is the function of this protein?
Cyclin partner of the cyclin-dependent kinase (CDK) PHO85.  Together with cyclin PCL8, negatively controls glycogen accumulation under favorable growth conditions.  The PCL10-PHO85 cyclin-CDK holoenzyme has glycogen synthase kinase activity and phosphorylates and negatively regulates glycogen synthase GSY2.  Also has minor GLC8 kinase activity.
What are the official names of this protein?
PHO85 cyclin-10.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. PHO80 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1A1_DAUCA
Sequence: MGKEKVHINIVVIGHVDSGKSTTTGHLIYKLGGIDKRVIERFEKEAAEMNKRSFKYAWVLDKLKAERERGITIDIALWKFETNKYYCTVIDAPGHRDFIKNMITGTSQADCAVLIIDPTTGGFEAGISKDGQTREHALLAFTLGVKQMICCCNKMDATTPKYSKARYDEIVKEVSSYLKKVGYNPEKIAFVPISGFEGDNMIERSTNLDWYKGPTLLDALDQINEPKRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGTIKPGMVVTFGPSGLTTEVKSVEMHHESLLEALPGDNVGFNVKNVSVKDLKRGYVASNSKDDPAKGAASFTSQVIIMNHPGQIGNGYAPVLDCHTSHIAVKFAELLTKIDRRSGKELEKEPKFLKNGDAGMVKMLPTKPMVVETFAEYPPLGRFAVRVMRQTVAVGVIKAVEKKDPTGAKVTKAAAKKGAK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COLL_DROME
Sequence: MEWGRKLYPSAVSGPRSAGGLMFGLPPTAAVDMNQPRGPMTSLKEEPLGSRWAMQPVVDQSNLGIGRAHFEKQPPSNLRKSNFFHFVIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQEQDIFVRLIDSVTKQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGTGNTSLSISGHPLAPDSTYDGLYPPLPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGTMLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRLQKLIPRHPGDPEKLQKEIILKRAADLVEALYSMPRSPGGSTGFNSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPHSSGGSYGATAASAAVAATANGYAPAPNMGTLSSSPGSVFNSTSMSAVSSTWHQAFVQHHHAATAHPHHHYPHPHQPWHNPAVSAATAAAV
What is the function of this protein?
May act as a 'second-level regulator' of head patterning.  Required for establishment of the PS(-1)/PS0 parasegmental border and formation of the intercalary segment.  Required for expression of the segment polarity genes hedgehog, engrailed and wingless, and the segment-identity genes CAP and collar in the intercalary segment.  Required at the onset of the gastrulation for the correct formation of the mandibular segment.
What are the official names of this protein?
Transcription factor collier, Transcription factor knot.
What is the protein family that this protein belongs to?
Belongs to the COE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SDHD_DESHY
Sequence: MTGKSPEVIPHTPVVQDLRAAREIFWINPHYRATKEFKEAQFGISLSDIHDAEERLRRFAPYLAKAFPETQPAQGLIESPIVPIKRMQSYLESRYGVQIPGDIWLKCDHQLPISGSIKARGGIYEVLKHAEETLIKQGLLTREDDYARLKDSSFRDVLSHYKIAVGSTGNLGLSIGVMGAELGFKVTVHMSADAKGWKKALLRSKGVEVIEYTSDYSKAVEEGRRQAEGDSRCHFIDDENSRDLFLGYAVAGLRLKEQLEKLNRKVDADHPLFVYLPCGVGGGPGGVTFGLKQVFQEHVHCFFAEPTHSPCMVLGLATGLHDGIAVQDIGLDNKTEADGLAVGRASRFVGKIMAGLLSGAFTVEDAELFRLLQALDHAEGIQCEPSALAGMAGPARLLLCKEGLQYIREHRLEEGLKRGTHLIWATGGSLVPVEVMKDYLSRGK
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: EX7S_ESCF3
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_CHLSY
Sequence: MRCPFCHFVETDVIDTRKLYEGEVIRRRRRCRACGRRFTTYERIESVSLMVVKKDGTREPYDREKIARGVRTACYRRPVSAAAIEQLVNDVETAIMNTDEHEISSQAIGDAVMQRLRDLDEVAYIRFASVYRAFTDIGKLREAVDELLDREGVRNGHLSPKPAEDS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: GALM_STRTR
Sequence: MKISCEIIGKVDSGDVSKISMENNNGVVISTLTTGATLQEFLVPMETGALKNIVLGFSDFEDYYKNNLCACQSIGRVAGRIGKASYTHNMVLYSLPKNEGDNCLHGGPKGMQVQNWNYVTNLNDDYVETKFIRRLYSSVDGFPGDVTVSISYRLNNNNRLTILFEAFDVTESTVFNPTNHVYFNLSDKQDLSSHELQIYSDYRLELDSELIPTGQKINVDETNYDFRKTTDLLPRIEANNGFDDAFVVGGGTCDHVKEVAILHDKESGDGIEIFSNRNGLVIFTMDDIEDNIYFARDKGKMAKRREAIAMEAQTLPDAVNHKGFGDIILDKGHSVNYEIGFQYFNSSR
What is the function of this protein?
Mutarotase converts alpha-aldose to the beta-anomer.  It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity).
What are the official names of this protein?
Aldose 1-epimerase, Galactose mutarotase, Type-1 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the aldose epimerase family.
Protein: HISZ_SYNY3
Sequence: MIHHPPAGARDLLPLEVAQKARINDQLQQTFHRWGYQRIVTSTLEWLDTLVAGGAISANNVIQLQDSGEGRLGLRPELTASIARAVVTRMTDNQPQRLCYRANVFRNPPEGYHGKQMEFFQAGIELLFAGGVRADAEILLLLTDCLTQLGLSDWQLILGDAGLTRSLLAKLPPTLQATVRDCITRLDYVELSQLPYPDNEAKNLALQLFDLRGTVEEVLARLGKLDLQGECLGLVDRLQALLCLVAASGDGPANLVLDLSWLQPFDYYTGMVFQAVSRQADNCYVLGQGGRYDQLLSQYHPQQQSFPGTGFSLNIEELHQCLLELGTLPTSTAPIDYLVCPVDDTAEGATFRHAQQLRRQHPDRRVELDLGGRSPEELNTYAQAMAVGQIVWVGADGPVDL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPSC_RALSO
Sequence: MKKVLVVFGTRPEAIKMAPLVKALQADTSMQCGVCVTAQHREMLDQVLRLFDIRPDYDLNVMKPGQDLYELTSNILTGVKSVLESFAPDLVLVHGDTSTTLATTLAAYYKQVPVGHIEAGLRTGNLYSPWPEEANRKVTGSLAALHFAPTERSRRNLLNEGVPADAVVVTGNTVIDALLSVRQRLQTDTALCRHTASLIPYRIGERRIVLVTGHRRESFGDGFERICAALASIARAHPDVDIVYPVHLNPNVREPVGRLLKGIDNIHLIEPLDYLPFVYLMDKAHIILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVEAGTVRLVGTSVDALVDSATTLLNDDSAYEAMSRAHNPYGDGAASARITRAIQAYFA
What is the function of this protein?
May be involved in synthesis of N-acetyltrideoxygalactose, a component of exopolysaccharide EPS I which functions as a virulence factor.
What are the official names of this protein?
Probable UDP-N-acetylglucosamine 2-epimerase, UDP-GlcNAc-2-epimerase.
What is the protein family that this protein belongs to?
Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU214_HUMAN
Sequence: MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNSSVQGFGGWRS
What is the function of this protein?
(Microbial infection) Required for capsid disassembly of the human adenovirus 5 (HadV-5) leading to release of the viral genome to the nucleus (in vitro).
What are the official names of this protein?
Nuclear pore complex protein Nup214, 214 kDa nucleoporin, Nucleoporin Nup214, Protein CAN.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Note=Cytoplasmic side of the nuclear pore complex.
Protein: GGGPS_METKA
Sequence: MGVFGYLRERTPCHLTLLDPVDVGPEEVPEVLESLVKAGTDAVMVGGSTAHASQVEAVVEAIREVADVPVILFPNGPEGLAPNADAVLFMSLLNSRNTYYLIEAQVKGAPLVERFGLESIPTGYLIVGEWGTTVSVVGDARVIPFDRVEVIVAYALAAKHLGMKAVYLEAGSGAPEPVPPEVVRRVSGIGVFTIVGGGIRSPETARELAEAGADAIVTGTAVERDPDLAAEIVEAIKDL
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_YERPN
Sequence: MVASGFLLIASFMLVLFVLSRPLGGFLARLIEGEPFSALQKVEAGLWRCSGVKNAEMNGWQYALAILCFNLLGIVLLFVLLMTQGSLPLNPEHLPGMSWHLALNTAVSFVTNTNWQAYSGENTLSYLSQMAGLTVQNFLSAATGIAVAFALIRAFARHSATTLGNAWVDLVRITLYVLLPIALIIALIFVSQGVLQNLDDYLHITTLEGVQQTLPMGPVASQEAIKVLGTNGGGFFGANSAHPFENPTAFSNFVQMLAIFLIPCALCFAFGQVVGDNRQGHALIWAMSLIFIVAVVVVMYAELAGNPHLSPLGADSNSNMEGKESRFGILATSLYAVVTTAASCGAVNAMHDSFTALGGMIPLWLMQIGEVVFGGVGSGLYGMLLFVLLTVFIAGLMIGRTPEYLGKKIDVFDMKMTALAILVTPTIVLLGTALALCTEAGRAGILNPGAHGFSEVLYALSSAANNNGSAFAGLSVNTPFYNLLLAAAMFIGRFGVILPVLAIASSLVAKKRQPAGNGTLPTGGLLFIGLLIGTVLLVGALTFIPALALGPVAEHLQVWLAH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOC_STAS1
Sequence: MIDVNNFHYMKIGLASPEKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFGPTKDWECSCGKYKRVRYKGMVCDRCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRALEEVIYFASYVVVNPGPTGLEKKTLLSEAEFREYYDKFPGKFTAKMGAEGIKELLEEIDLDAELKHLRDELESATGQRLTRAIKRLEVVESFRHSGNNPAWMILDVLPIIPPEIRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIAVGPSLKMYQCGLPKEMALELFKPFIMKELVQREIATNIKNAKSKIERMDDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLATTAYNADFDGDQMAVHVPLSKEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLERKEAVNTGTIYNDTNEVLKAYANGYVHLHTRIGVHAASFNNPTFTEEQNKKILLTSVGKVIFNEIIPDSFAYINEPTQTNLENKTPEKYFIAPTEIGEEGLKAYFDEQPLIKPFNKNFLGNVIAEVFNRFSITDTSMMLDRMKDLGFKFSSKAGITVGVSDIVVLPDKQDILDEHEKLVEKVTKQFNRGLITDFERYNAVIEIWTDAKDQIQNELMGSLEKTNPIFMMSDSGARGNASNFTQLAGMRGLMAAPSGEIIELPITSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIVREEDCGTDRGLLVSDIKEGTEMIEPFIERIEGRYSKETIRHPETNEVIVNPDELVTAEIAKKITDAGIEEMYIRSAFTCNTRHGVCEKCYGKNLATGEKVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEARNPKGQAVITEIEGVVDDIKLAKDRQQEIVIKGANETKSYLASGTSRLKVEVGQSVERGEVLTEGSIEPKNYLSVSGLNATESYLLKEVQKVYRMQGVEIDDKHVEVMVRQMLRKVRIIEAGDTKLLPGSLVDIHNFTDANREAFKERKRPATAKPVLLGITKASLETESFLSAASFQETTRVLTDAAIKGKRDNLLGLKENVIIGKLIPAGTGMRRYRDVEYDKAAPETEIVEEVQTTEI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: Y1243_METJA
Sequence: MSRRGRPKIPRFISEEPKFRIFKPHGVSLTEVDKVILSVDELEAIRLVDYLDYTQEEASKLMGISRRVLWSLLTEGRKKIADALINGKAIVIEGGEYKIRECGFCMRHRFGIKKHCRTWREEL
What are the official names of this protein?
UPF0251 protein MJ1243.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: YCF3_CYAM1
Sequence: MSRSQKNDNFIDKTFTILADVLVKLLPTSQNAKKAFSYYREGMAAQAEGEYAQALESYYHALEFEEDVIDRSYIIYNIGLIYASNGEDEQALEYYHQALELNPRLVQALNNIAVIYHKQGMTYQDEQLLQKAAAYWRKAIQLAPGQYLEAQNWLKNMV
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GSA1_CENSY
Sequence: MGSRGLFERARKVIPSGVNSPVRYYAPYPFFAASASGGSIRDADGRKYTDLCNGYGALLLGHGRGEVVRAVSAQLRRGTLFCVPTEQEVELARLISGNYPSMESTRLVNTGGEATMTAIRLARGFTKRDRIIKFDGCYHGAHGSVLVKAGSGSAHLGISTSEGVPRGLARQTTVIPYNDEAAFEGAAADDVAAVIVEPVMGNMGVIPPKKGFLRLLRKLSSRLGMQLIFDETITGFRLSAGGAQEAFGVRPDITTLAKALGGGLPIAAVGGKKNIMERLAPGGSVYEASTFAGNPVSVSAALASIRTINRIKGRLYPRLERAAAALASSIADDAADLGLDRQINRVASIFQVFFTAEPVTDAASAKRADAARFDKMFRALLKNGVFVAPSQFEMASLSAAHTVEDLRNVSAAYRTALGAAR
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRM8_RAT
Sequence: MVCEGKRLASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKERCPGYIGLCPRMVTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQINNKSTEYKIIGHWTNQLHLKVEDMQWANREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNINRTGCQRIPIIKLEWHSPWAVVPVFIAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRIFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHTIIDYGEQRTLDPENARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTYISYSNHSI
What is the function of this protein?
G-protein coupled receptor for glutamate.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.  Signaling inhibits adenylate cyclase activity.
What are the official names of this protein?
Metabotropic glutamate receptor 8, mGluR8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.