PharMolix/UniProtQA huggingface dataset:
Protein: NU155_ARATH
Sequence: MSQDDEIVMRDVTSAGICIGDRIGREAASQLDLEEALEASRYASHPYSTHPREWPPLIEVGETWELPSVLIERYNTAGGEGTALCGIFPEIRRAWASVDNSLFLWRFDKRDGQCPEYSGEEQAICAVGLAKCRPGVFVEAIQYLLVLATPVELVLVGVCCTEGPDGRDPYAEISVQPLPDYTISSDGVTMTCVTCTNKGRIFMAGRDGHIYELLYTTGSGWNKRCRKVCLTAGVGSMISRWVVPNVFKFGAVDPVVEMVVDNERQILYARTEEMKLQAYVSGPNGEGPLKKVAEERNLLNQKDLSQGNRQSAVAGRSNKPSIVSISPLSMLESKWLHLVAALSDGRRMYLSTSSSGSGSTISFSGFNNHRQTPNCLKVVSTRPSPPLGVGVGLGFGAASVAGRTQNDDLSMKIETAYYSVGTLVLSDSSPPAMSSLLVVSRDSSVHSQAGSSSGPSSRSSRALREVVSSLPIEGRMLFVADVLPSPDTAATIQSLYSELEYCGVEVSGESYEKACGKLWARSDLSTQHILPRRKIVVFTTMGMMELVFNRPVDILRRLLESNSPRSLLEDFFTRFGVGEAAAMCLMLAARIINFEDLISNIVADKAAEAFEDPRIVGMPQFDGSSGLSNTRTATGGFSMGQVVQEAEPIFSGAHEGLCLCTSRLLFPLWELPVMSKKTSSDTMSEDGVVICRLSTSAMHVLESKIRSLEKFLRSRRNQRRGLYGCVAGLGDVTGSILYGTGSELGATERNMVRNLFGAYSNGGESANKRQRLPYSPAELAATEVRAMECIRQLLLRSAEALFLLQLLSQHHVARLVQELDANLKQALVQLTFHQLVCSEEGDQIATRLISAVMEYYTGSDGRGTVDDISPRLREGCPSYFKESDYKFYLAVERLERAALTSDAEEKENVAREAFSFLSKVPGSADLQTVCKRFEDLRFYEAVVCLPLQKAQALDPAGDAFNDQLDASIREHALAQRKQCYEIIANALRSLASPLASPTLDEASRSQYICQIVHLGVQSTDRAFREYLYKAMIELHLENELLEYGGPDLVPFLQNAGSHSESQVGAVSTGSSPLGHSGTQISSDQAKYFDLLAKYYVSKRQHVLAAHVFLRLAERRAISLGDSPTLERRRDDLSQAVLQAKNASNSDGLVGSAQGVSDSGLLDLLEGKLAVLQFQIKIRDKLEAIASNFESSVAMQDSDQNGQVLDGDSSDDTNLANAANEMAMEVSSELKSVTQLYNEYAVPFELWEICLEMLYFANYSGDADSSIIRETWARLIDQALSQGGIREACAVLKRVGSHIYPGDGVVLPLDVLCLHLERAALERSERIENVRDEDIAKALLAACKGAAEPVLNAYDRLLSNAAVVPSPNLRIRLLRSVLVVLREWAMSVLSDRMGSSPTRSSLILGGSFALENKAALNQGARDKIANAANRYMTEVRRLALPPNKTDGVYAGFKELDESLLSPFSF
What is the function of this protein?
Major component of the nuclear pore complex (NPC).
What are the official names of this protein?
Nuclear pore complex protein NUP155, Nucleoporin 155.
What is the protein family that this protein belongs to?
Belongs to the non-repetitive/WGA-negative nucleoporin family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex.
Protein: EF2_THEKO
Sequence: MGRREEMIAKIKELMTQPERIRNMGIAAHIDHGKTTLSDNLLAGAGMISEELAGKQLVLDFDEQEQARGITINAANVSMVHNYEGNDYLINLIDTPGHVDFGGDVTRAMRAIDGAIIVVDAVEGVMPQTETVLRQALREYVKPVLFINKVDRLIKELKLTPQQMQERFVKVITDVNRLIRRYAPPEFKDKWLVKVEDGSVAFGSAYYNWALSVPYMKKTGVSFKDIIDLTNAGDLKTLRKKAPLHVVVLDMVVKHLPNPLEAQKYRIPHLWRGDINSDVGQAMMNCDPKGPMTMVVTKIILDKHAGEVATGRVWSGTVKTGQEVYLINSKRKARIQQVGIYMGPERINMEAVPAGNIVAVTGLRDAMAGETVSVQQIEPFEALHYTSEPVVTVAIEAKNVKDLPKLVEALRQLAKEDPTLHVKIDEETGQHLLSGMGELHLEVKLHRLKTEWKLDVEVSPPIVVYRESVTKQSPIVEGKSPNKHNRFYITVEPMPDEIYQAIREGEIPEGRPKDPKAVAKKLAELGMDYEIAKGIVDIYNGNMFLDNTKGIQYLNEVMDLLVDGFHQAMDEGPLAKEPVMKVIVRLHDAKIHEDNVHRGPAQIYPAIRSAIHCAMMKAGPVLYEPYQKVIINVPYEYMGAVSRELNQRRGQLIDMRQEGEVMIIIGEAPVAEMFGFAGAIRGATSGKALWTTEHAGFKRVPNELAQQIIRQIRQRKGLDPNPPKEQDVCPQQ
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADY3_YEAST
Sequence: MNHWLAFLNKPESLKEQNSDCDQQGEMRHVTDGTLTKSPESKPFRERRSQTWIDSEVPTSTEKSNVQESISSDIISKLSNRRSRRNRSESWAGSEASSPSGNISTLENATEKNTLKSPNKFLQRGGLPTVGIGSQALSPAGKPSTLGNVSPGKFTTYKVHNSIEVNRFSSTPTKLLTNPHKVAAISNDEHYVVSNESLEENIEVAHLENVFRSSKTPDEEQSEYMKLGEIRLSSSSYGGSISKENSLPKVLDELQSQNEEIKALRQKLEEKDDRIQELEELNSMNDAKLQRIEDLQKEFHNERKAASKRLNIVQDRFRKEIKKIREEKITDFQNKNASKKEKNEVTSAKTKCKAFSQRNILVSELYRKQKQILNLQQENDKFLKDINESNNSIVKLRSEVEILKSNLQLSQDENKKLHDNGSFYEKRLNDVYSYMQNLSLFEKDLGKFILEEMKCGHSPSMFQNGFAKLYPDFQDIKNLENMEQYKQLKGKIELLEKNDRIRLEKIISVFKLINERLHFMQQQHSHKIKYLQKEALTKEQQFRLEKRRWHDILNLKEENFQKLKSELKEKLILSEKIQKNAEDKLNDYMNEHQEIVEKLQNQALIASRWSTQIQESENTHKKITDELAGKQSEILKLEETILSLKEDVFQEKLNLKKLYGDPSTELNFETVGKSFPHITKEKYDSLGLDILTDLTYVQSQNLIKNLLIVLDIPLKTFLKIVPTIVIQLRCELTLLTKFANDLNLKVFGKQLDFKSRRKVAMNEFLNNHDIAEVKHPLEYDLQALFKYFFS
What is the function of this protein?
Involved in the pathway that organizes the prospore membrane (PSM) during sporulation.  Mediates the assembly of the DON1 ring structure at the leading edge of PSM during meiosis II.  May constitute a physical link between SSP1-containing PSM precursors and the spindle pole body (SPB) and may facilitate the recruitment of other factors that are required to promote spore wall formation.
What are the official names of this protein?
Accumulates dyads protein 3.
What are the subcellular locations of this protein?
Prospore membrane. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Localizes to the leading edge, which cover the ring-shape opening of the PSMs during meiosis II. Colocalizes with DON1 to dots in the cytoplasm and at the SPB. Its localization to the PSMs but not to the SPBs depends on SSP1.
Protein: YHIT_AQUAE
Sequence: MQEKDCIFCKIVRGEVPAKKVYEDDKVLAFHDINPVAPVHILIIPKKHIMGIQTLEPEDECLVGHMFYVARKIAEDLGIAPDENLNKGYRLVFNVGKDAGQSVFHLHLHLIGGREMSWPPG
What are the official names of this protein?
Uncharacterized HIT-like protein aq_141.
Protein: Y953_METJA
Sequence: MRLLGVIGYLAVLIKAICESWVDVVKRSINGEIHPQVIEIESIINNPTGLVLLSWSITATPGTLVIDLIPEERKLKVAVISPRSREDIVPFEPYIKKIFD
What are the official names of this protein?
Uncharacterized protein MJ0953.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISY1_HUMAN
Sequence: MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQIQNAGLGEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGYKYFGAAKDLPGVRELFEKEPLPPPRKTRAELMKAIDFEYYGYLDEDDGVIVPLEQEYEKKLRAELVEKWKAEREARLARGEKEEEEEEEEEINIYAVTEEESDEEGSQEKGGDDSQQKFIAHVPVPSQQEIEEALVRRKKMELLQKYASETLQAQSEEARRLLGY
What is the function of this protein?
Component of the spliceosome C complex required for the selective processing of microRNAs during embryonic stem cell differentiation (By similarity).  Required for the biogenesis of all miRNAs from the pri-miR-17-92 primary transcript except miR-92a (By similarity).  Only required for the biogenesis of miR-290 and miR-96 from the pri-miR-290-295 and pri-miR-96-183 primary transcripts, respectively (By similarity).  Required during the transition of embryonic stem cells (ESCs) from the naive to primed state (By similarity).  By enhancing miRNA biogenesis, promotes exit of ESCs from the naive state to an intermediate state of poised pluripotency, which precedes transition to the primed state (By similarity).  Involved in pre-mRNA splicing as component of the spliceosome.
What are the official names of this protein?
Pre-mRNA-splicing factor ISY1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ISY1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YMF20_MARPO
Sequence: MLIVVNDSPFYKGDTAILRQLVGGDRISCKLKHANVRHEFSYSGWVLIVGNEYLGMSETSGALARRMIVFPARNAVHLKKFLIKEEHGLFMGPLAEEISEIAKWALSMPDQDATEIMRDPEIHCPSLSEENKLCRENLNHISACLMKTPCSSSKPSQGICHAHDPIS
What are the official names of this protein?
Uncharacterized mitochondrial protein ymf20, ORF167.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YONC_BACSU
Sequence: MATRLQKALTEVGNHTTGNLNSLKIKTVAHGAKVTGSDIDNFMLVELGFDAEGNRTASKLSDKTKKAYLIASPEARYLGESMRDFYNGVGEHARIVILEPAYTRFDVSAFSFNTGVTEVKQGQVAHFDIATQKYILSDPTSPHEDYADSSAKFLVVNNEDDLVYTMGQKLVRLEVIEA
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YonC.
Protein: DNAA_LEPBL
Sequence: MNLAWNKILEEVSKKISPQYYERFIDTLKLETLNSEKCTIIAPSATIKTHVERKYQSIIENAILEACGDKIPVEILIETKATSPLQSFLEKSFDQKDFQFNPDYTFETFIVGDCNRLAYTAAKECVRKPAEINPLYLFGSVGVGKTHLLHAIGSELIKKDPWKTVCYIDISSFMNEFRFALQSRELIESFKIKYQSYNCLLVDDIQLLSTNAEKTQDEFFALFNFLFERKRQIVIASDRPSSELTIHERLKSRFVTGVQADIQYPNKEIRKGIVTSHSKIMDLGLSEDVLEFLADQIEEDTRLLLGALNDIYLYKKSYSLLFLNLDKVKEIVKNRLYRKKNVEFSHDRIIESVAKEFNLDAAEIMGKSRKKELIIPRHICFYLLHNVFNVNKSQVGRLFQTQHTTVIHGLRKTEELLSDNKEIRFLVERISSKYKLQ
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMS1_ICTPU
Sequence: MPSTRIQCALALLAVALSVCSVSGAPSDAKLRQFLQRSILAPSVKQELTRYTLAELLAELAEAENEVLDSDEVSRAAESEGARLEMERAAGPMLAPRERKAGCKNFFWKTFTSC
What is the function of this protein?
Somatostatin inhibits the release of somatotropin.
What are the official names of this protein?
Somatostatin-1, Somatostatin I.
What is the protein family that this protein belongs to?
Belongs to the somatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPB_MYCGI
Sequence: MTSTEEKTTSGRVVRITGPVVDVEFPRGSVPELFNALHADITYKELSKTLTLEVAQHLGDNLVRTISMQPTDGLVRGVEVTDTGNSISVPVGDGVKGHVFNALGDCLDEPGYGKDFEHWSIHRKPPPFSELEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELEDANVLKDTALVFGQMDEPPGTRMRVALSALTMAEFFRDEQQQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRTVFSKGIFPAVDPLASSSTILDPAVVGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELAEEDKQLVQRARRLERFLSQNMMAAEQFTGQPGSTVPLKETIEAFDKLTKGEFDHLPEQAFFLIGGLDDLAKKAESLGAKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TB15A_HUMAN
Sequence: MSDKPDLSEVEKFDRSKLKKTNTEEKNTLPSKETIQQEKECVQTS
What is the function of this protein?
Plays an important role in the organization of the cytoskeleton.  Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
What are the official names of this protein?
Thymosin beta-15A, NB thymosin beta, Thymosin-like protein 8.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YSAB_SALTY
Sequence: MIMKYFCSVMIAIALVGCTATPPPTQKAQQSKVSPTRTLDMEALCKAQAAQRYNTGAQKIAVTGFEQFQGSYEMRGNTFRKESFVCSFDADGQFLHLSMR
What are the official names of this protein?
Uncharacterized lipoprotein YsaB.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: HIS6_FRAP2
Sequence: MLTKRIIPCLDVKDDVVVKGVKFRNHRIIGDIIELAQKYSDAGADELVFYDIGASPDNKLLSIKWIQEIAKKINIPFCVAGGIKSVENARAILNEGADKISVNSAALARPDLIDELVYEFGSQCVVVGIDSKFIDGEFKVCQYTGSADKTVQTLLDPVSWAKEVESRGAGEIVLNCMNQDGVKGGYDLEHLREVQSNVSIPVIASGGAGEIQHFIDVFKYTEIDGALAASVFHDDIIAIPELKQELFKNNIPTRIVK
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_GEOSW
Sequence: MNLVLMGLPGAGKGTQAEKIVETYGIPHISTGDMFRAAIKEGTPLGLQAKEYMDRGDLVPDEVTIGIVRERLSKDDCQKGFLLDGFPRTVAQAEALENILAELNRSIDYVIHIQVDKDILMERLTGRRICKNCGATYHLVFNPPAKSGVCDKCGGELYQRADDNEETVANRLEVNIKQTQPLLEFYEKKGYLRHINGQQDIEKVFADIRELLGGLQ
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1312_VIBC3
Sequence: MVFVNSRHQGNHYEQMAADYLRRQGLTLVTQNVNYRFGELDLIMRDGNTLVFVEVRYRNNTQHGHAAETVTRTKRARLIKAANCWMLANKMNSHSADFRFDVIAIHQQGQHIDWLKNAITEG
What are the official names of this protein?
UPF0102 protein VC0395_A0112/VC395_0597.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: VE7_HPV32
Sequence: MRGNAPTLKDIILYDLPTCDPTTCDTPPVDLYCYEQFDTSDEDDEDDDQPIKQDIQRYRIVCGCTQCGRSVKLVVSSTGADIQQLHQMLLDTLGIVCPLCACVE
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: ALLB_RUBXD
Sequence: MSAFDLIVRGGTVVRGGCEVADVGVADGVISAVGPDLEGGAREEIDARGLLVLPGAIDAHVHFNEPGRTRWEGFASGTRALAAGGTTLCVEMPLNAHPPTTDGESFDLKLAAAKASAHVDFALWGGIVPGRVGRMEELAGRGVAGFKAFMSATGTPDFEAADDLTLYEGMQEAARLGLPVLVHAENRQITDALARRATSALRTTMRDYLASRPAVAELEAIGRAILLASEAGCSLHIVHVSTGRGVALVAAARERGVDVTCETCPHYLLFTDEDAVRIGAAAKCAPPLRPREEVESLWEQVLAGNVAFVTSDHSPCPPDMKAGEDMFRAWGGISGCQSLLPALLDEGYHGRGLPPERLAELLSANVARRFGFAGKGGIEEGNDADLALVDPSGEHVLREEDLHYRHPISPYVGRSFRGRVVRTILRGRTVFEGGRVVSGPAGRFVRPQREKGER
What is the function of this protein?
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
What are the official names of this protein?
Allantoinase, Allantoin-utilizing enzyme.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
Protein: AMYA_VIGMU
Sequence: MDSFSRLSIFCLFISLLPLFSSPALLFQGFNWESSKKGGWYNSLKNSIPDLANAGITHVWLPPPSQSVSPEGYLPGRLYDLDASKYGSKNELKSLIAAFHEKGIKCLADIVINHRTAERKDGRGIYCIFEGGTPDSRQDWGPSFICRDDTAYSDGTGNNDSGEGYDAAPDIDHLNPQVQRELSEWMNWLKTEIGFDGWRFDFVKGYAPSISKIYMEQTKPDFAVGEKWDSISYGQDGKPNYNQDSHRGALVNWVESAGGAITAFDFTTKGILQAAVQGELWRLIDPNGKPPGMIGVKPENAVTFIDNHDTGSTQRLWPFPSDKVMQGYAYILTHPGTPSIFYDHFFDWGLKEQIAKLSSIRLRNGINEKSTVKIMASEGDLYVAKIDNKIMVKIGPKMDLGNLIPSNLHVATSGQDYAVWE
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: SMTN_HUMAN
Sequence: MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELEREEEALASKRFRAERQDNKENWLHSQQREAEQRAALARLAGQLESMNDVEELTALLRSAGEYEERKLIRAAIRRVRAQEIEAATLAGRLYSGRPNSGSREDSKGLAAHRLEQCEVPEREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPGSPEPPPSPPKTTSPEPQESPTLPSTEGQVVNKLLSGPKETPAAQSPTRGPSDTKRADVAGPRPCQRSLSVLSPRQPAQNRESTPLASGPSSFQRAGSVRDRVHKFTSDSPMAARLQDGTPQAALSPLTPARLLGPSLTSTTPASSSSGSSSRGPSDTSSRFSKEQRGVAQPLAQLRSCPQEEGPRGRGLAARPLENRAGGPVARSEEPGAPLPVAVGTAEPGGSMKTTFTIEIKDGRGQASTGRVLLPTGNQRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARLGSVTHVTSFSHAPPSSRGGCSIKMEAEPAEPLAAAVEAANGAEQTRVNKAPEGRSPLSAEELMTIEDEGVLDKMLDQSTDFEERKLIRAALRELRQRKRDQRDKERERRLQEARGRPGEGRGNTATETTTRHSQRAADGSAVSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGSTMMQTKTFSSSSSSKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEKEGAAGSPGGPRAAVQRSTSFGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAEMLVDCVPLVEVDDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV
What is the function of this protein?
Structural protein of the cytoskeleton.
What are the official names of this protein?
Smoothelin.
What is the protein family that this protein belongs to?
Belongs to the smoothelin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Exhibits a filamentous organization.
Protein: Y1001_BACAN
Sequence: MIVTTTSGIQGKEIIEYIDIVNGEAIMGANIVRDLFASVRDVVGGRAGSYESKLKEARDIAMDEMKELAKQKGANAIVGVDVDYEVVRDGMLMVAVSGTAVRI
What are the official names of this protein?
UPF0145 protein BA_1001/GBAA_1001/BAS0936.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RRF_OLEA2
Sequence: MDTILLETEERMEKAVAALDREFGRLRTGRASTSLVDSIKVDYYGTPTPINQLASVAVPDSRTITIQPWDRGAFALVEKAIMQSDLGLTPINDGKIIRISMPPLTEERRKELVKVAKKYTEDAKVAVRNIRRDANEQIKKMEKDKAITEDDMKRGQDEVQKLTDAFVAKSEKVLAKKEKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3454_BACAA
Sequence: MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAAVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSAGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINEIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDHHVS
What are the official names of this protein?
UPF0316 protein BAA_3454.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPO4_SHEPA
Sequence: MQKIIHVDMDCFYAAVEMRDFPELRGKPIAVGGRSDRRGVISTCNYEARQFGVRSAMASGYALKLCPDLILVPGRMQVYKEVSSQIRAVFERYTYLIEPLSLDEAYLDVTDSPHCKGSATLIAEAIRADILAETGLTASAGIAPVKFLAKIASDLNKPNGQYVIRPDMINEFVKTLPLIKIPGVGKVTAKKLADLGLHTCSDVQAYPPAQLIERFGKFGTVLIERSKGVDKRGISPNRERKSVGVETTLAKDIHTLEQCRAVMPQLIQELGARVSRSAKDRTIHKQVVKIKFEDFKQTTIEHRSDDISVNLFYQLLEQAMERQHERGIRLLGVSVGLASNSSTTDDSDVDSSQLDLGF
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_DESDA
Sequence: MGQKVHPFGFRLGYNKNWQSRWFSKKEYPAFVYEDSKIRAFVKKLLYHAGLSKIEIERAGGKVRLILSTARPGIVIGRKGVEIEKLRNDLRQKFGREFSLEVNEIRRPEVDAQLVAENIAQQLERRVAFRRAMKRTVSMARKFGGEGIKVTCSGRLAGAEIARTEWYRDGRVPLQTLRADIDYGFAEARTTYGIIGVKVWIYKGEILDKEVDQ
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: FSD1L_HUMAN
Sequence: MDSQKYCFKENENVTVDKACFLISNITIGPESINLQQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSENGMTGSASSLNNVVTQ
What are the official names of this protein?
FSD1-like protein, Coiled-coil domain-containing protein 10, FSD1 N-terminal-like protein.
Protein: PROF_ODILC
Sequence: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations inhibits spontaneous rabbit actin nucleation.  This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.
What are the official names of this protein?
Odin profilin.
What is the protein family that this protein belongs to?
Belongs to the Asgard profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DGCR6_MOUSE
Sequence: MDRYAAAGDEAADRARQQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQRLRLQNEHRVLRQTLRQKHLEAQQSCRPHNLPVLQAAQQRELEAMEHRIREEQQAMDRKIVLELDRKVADQQSTLEKAGVAGFYVTTNPQELTLQMNLLELIRKLQQRSCQVGKAAL
What is the function of this protein?
May have a role in early embryogenesis.
What are the official names of this protein?
Protein DGCR6, DiGeorge syndrome critical region 6 homolog.
What is the protein family that this protein belongs to?
Belongs to the gonadal family.
Protein: RL25_VIBPA
Sequence: MKFEAVVRTELGKGASRRLRHAGKFPAVVYGGEEAAVAIVLNHDDIVNQMDKPEFYEGIVLVIDGKEVKVKPQDVQRHAFKPKVEHMDFIRI
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: DDL_CAMC1
Sequence: MNLGVIFGAKSFEHEISIVSAIVLKNVLKQGLKFIFCDANRDFYLIEQKDMRANFFSSGKYKNSKKLSLAKGGFYTHSLFGANKVECDVIINLIHGMDGEDGKIAALFEFYGVKYIGPRLEASALSYNKELTKFLAQKAGVKALDYEMLTRQSEPKFHYPIILKPARLGSSIGVSVVHDDSELAYAKDVAFEFDKDVLVEPFIKGVKEYNLAGCRIDGKIKFSIVEEPKKKEFLDYEQKYLSFSNENKVKEAEISEELKQKLKFNFSKIYDCGFDGAIIRCDFFVIDDEVYLNEINPNPGSLANYLFEDFESTLNALANSLPKEREIKIDYKFINSITSVKGSGKL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.