PharMolix/UniProtQA huggingface dataset:
Protein: IABN_GEOSE
Sequence: MVHFHPFGNVNFYEMDWSLKGDLWAHDPVIAKEGSRWYVFHTGSGIQIKTSEDGVHWENMGWVFPSLPDWYKQYVPEKDEDHLWAPDICFYNGIYYLYYSVSTFGKNTSVIGLATNQTLDPRDPDYEWKDMGPVIHSTASDNYNAIDPNVVFDQEGQPWLSFGSFWSGIQLIQLDTETMKPAAQAELLTIASRGEEPNAIEAPFIVCRNGYYYLFVSFDFCCRGIESTYKIAVGRSKDITGPYVDKNGVSMMQGGGTILDEGNDRWIGPGHCAVYFSGVSAILVNHAYDALKNGEPTLQIRPLYWDDEGWPYLSV
What is the function of this protein?
Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall.  Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of debranched arabinan, linear arabinan and short arabino-oligosaccharides (degree of polymerization from 2 to 8).  It exhibits marginal activity toward sugar beet arabinan.
What are the official names of this protein?
Intracellular endo-alpha-(1->5)-L-arabinanase, ABN, Endo-1,5-alpha-L-arabinanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPKOW_XENLA
Sequence: MAAAGSSQAPISFGFNRSSKKKLLVSDGEKEEEHEKEYLVGAEGKELLSANPAPESKPLVIPLIHKNRWAKPNKDKEEDAAPQTEDEAVLSQAVKELIEESRRAQEDNSETNQTLSIPLLMQNRMPDGYEDREKVDVSLRPDSAEAADYDVVPVQQYGMAMLRGMGWKEGEGIGRTFKQDVKPLEQKLRPKGLGLGADRSALKHLEPQKPRKPLKPGEEPEEESKGLGTGSAVQIQSGAYKDMYGKVEGIDPDNSRAMITLAIGGKVVTVSLFSLRLVNSAEYTKYAKDLSRLSKVHQESKVEPHRDRTPEKEQGRKGGEKRSESSRNADVKLSKSSGNGDSNNREKRHRQRSPEQEKEKKKIRPEPHGWLRRDIRVRFIDKNYKGGKYYNSKMLVEDVLSPTRCVCRTENGCILEDIRQDMLETIIPKEEGEHVMVVLGKYRGMVGKILHRDKQKSRALVQLQGEHDSAETLSYDAICHYTGAQDD
What is the function of this protein?
RNA-binding protein involved in pre-mRNA splicing.
What are the official names of this protein?
G-patch domain and KOW motifs-containing protein.
What is the protein family that this protein belongs to?
Belongs to the MOS2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDPA_RHOPA
Sequence: MTFIGWCQIALFGAVVVALVKPLGWYMTRVFAGEWTPLTPVLRPVETMLYRAAGVDPKQEQHWLTFTLAMLLFHIGGFAIIYAVLRLQALLPFNPAEQGAVAPDLAFNTAISFLTNTNWQNYGGESTLSYLSQMLALTHQNFLSAATGIVLAMALIRGFSRASVRTIGNFWVDITRCTLYVLLPICIPYALFLVWQGMPQTLGSYVDATTLEGAKQTIAVGPVASQVAIKMLGTNGGGFFNANAAHPFENPTALSNFVQMLSIFVLGAALTNVFGRMIGNQRQGWAILGVMGVLFVVGIAVAYWAEASGTATLDALGITGGNMEGKEVRFGIVASALFAVVTTAASCGAVNAMHDSFTALGGMIPLINMQLGEIIVGGVGAGLYGMLLFVVLAIFVAGLMVGRTPEYVGKKIEAREVKMAMLAILVLPLMYLGWTAIAVVLPSAVASMGNAGPHGFSEVLYAFTSATANNGSAFGGLTGNTFFYNLTLATAMFVGRFMMIVPTMAIAGSLAGKKLVPPSAGTLPTTGGLFVGLVVGVILIIGGLTFFPALALGPIVEQVSMSAKTLF
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATE_SULIM
Sequence: MSELNYEELGLKVGLEIHQQLNTSHKLFCNCSTNLKEDYKLTLERYLRPALSELGEVDVAALFEWKKGKKYVYRIPITTSCLVEADEEPPHAINEEALKIALAIAIALNSNIVDEIYVMRKIVIDGSNTTGFQRTAIVALGGMLKDEGVTIQTIAVEEDAARKIDERTDQVTYSLDRLGIPLIEISTGPDIRSPEQAERVALKIGQLLRMTGKVKRGIGTIRQDLNISIKGGTKIEIKGVQKLELIPDIVRYEAMRQFNLLKIKEELNKRGVSKNLILSNFVVKDLTELFKNTNSKIIKSGIEKGGLVYGIRAYKLKGILGWELIPKKRRFGTEIADYVRALAELGGLFHSDELPNYGITEEEINKVREALNATTEDGFILIVGERERLDKAVEVIRDRILLAFDGIPKETRGALDDGTTKFLRPQPSSARMYPETDIPPRRIDEKLLEDAKKFVPESPESKMKRYITLGLSEELAKEIIRDPRLDLFEELVNKYSPKVSPVVIASTITNTLKYVKSKGGDISKINEEDIEELIKSVYENKISKDSISEILLEYTTNKNVELKDVIRKYEALPTEELEKIIDDVISSNLDEIRKRKDKAVNLIMSKVMSKVKGRAEGKVILELIKSRLKNVME
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: PLCD_PONAB
Sequence: MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRFTEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTLLGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTEIDKGSAYGNSGSKQKLND
What is the function of this protein?
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity).  Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity).
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase delta, 1-acylglycerol-3-phosphate O-acyltransferase 4, 1-AGP acyltransferase 4, 1-AGPAT 4, Lysophosphatidic acid acyltransferase delta, LPAAT-delta.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y1086_STAAR
Sequence: MAKQTTMKNAALKQLTKDADEILHLIKVQLDNLTLPSCPLYEEVLDTQMFGLQKEVDFAVKLGLVDREDGKQIMLRLEKELSKLHEAFTLV
What are the official names of this protein?
UPF0358 protein SAR1086.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: TRBID_DROME
Sequence: MCDTKDDAQKWKCETCTYENYPSSLKCTMCQASKPLLNEDIFRLSPAQESCTVAEEAAAVEVAVMSPTPSSTCYSLQPQSQARQSNVADSEKWPCKVCTYLNWPRSLRCVQCCTKRGGEAIERGKKDMDNEADGDRAGEALQALRISGSEENLANKPVQLIGATASHRLSLSRGIDDATHLNNLANASHNQSQSQHRQPVLQQQMQLQLQPQQQRESSSSAAVPPQQQKQCYVSKWACNSCTYENWPRSIKCSMCGKTREREISGSQNDLHASSSLNSQEENQQQLQQPNVDTVSVNNSFNKKHIYQLGSSETINNCDTLQERQERRQRQIRRQVDWQWLNACLGVVENNYSAVEAYLSCGGNPARSLTSTEIAALNRNSAFDVGHTLIHLAIRFHREEMLPMLLDQISGSGPGIKRVPSYVAPDLAADIRRHFANTLRLRKSGLPCHYVQKHATFALPAEIEELPIPIQEQLYDELLDRDAQKQLETPPPALNWSLEITARLSSRMFVLWNRSAGDCLLDSAMQATWGVFDRDNILRRALADTLHQCGHVFFTRWKEYEMLQASMLHFTLEDSQFEEDWSTLLSLAGQPGSSLEQLHIFALAHILRRPIIVYGVKYVKSFRGEDIGYARFEGVYLPLFWDQNFCTKSPIALGYTRGHFSALVPMEPFTRIDGRRDDVEDVTYLPLMDCELKLLPIHFLTQSEVGNEESMMRQWLDVCVTDGGLLVAQQKLSKRPLLVAQMLEEWLNHYRRIAQVITAPFIRRPQITHYSSDGDSDEE
What is the function of this protein?
Positive regulator of the Wnt signaling pathway.  Specifically cleaves 'Lys-63'-linked ubiquitin chains.  May act by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription (By similarity).  Required for an efficient wg response, but not for other signaling responses, in the eye.
What are the official names of this protein?
Ubiquitin thioesterase trabid, dTrbd.
What is the protein family that this protein belongs to?
Belongs to the peptidase C64 family.
Protein: Y194_CITBB
Sequence: MRMNLSELEIRILGCLMEKELATPEIYPLTLNALASACNQKSNRDPVMSVTEADLLRGLEALGARGLARLTTTGGRVAKYCHSATDNLRLAAAERAVLAELMLRGAQTAAELRSRGERMTEMGDIESVEETLRKLQQHGPPLVVRLPRQPGRKEQRYLQVFAGLPEFPDELDISEEMEPAAGPRAAAGRPAVGNERLERLEEGIGSLRQEIAALRREVQEMMDAFA
What are the official names of this protein?
UPF0502 protein Gbem_0194.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: RL18_BRUA2
Sequence: MASPKETLQRRAARVRRQVKAVANGRPRLSVHRSSKNIYAQIIDDVRGVTLAAASTLDGDLKGKLKTGADSAAAAAVGKLVAERAVKAGVKDVVFDRGAFIYHGRVKALAEAAREGGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RECX_KLEP7
Sequence: MTEPSSRRSGYARLLDRAIRILAMRDHSEQELRRKLVAPVMSKNGPEALDVTPDELEQVVAWCIENRYLDDNRFVGQFIASRSRKGYGPARIRQELSQKGIARQVVDQAMRECDIDWVSLAREQAQRKYGEPLPSAFTEKVKVQRFLLYRGYLMEDIQEIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AC4CH_VIBC1
Sequence: MSSHPTKITFFEFLTPLITAGKKTITIRDESESHYVPNTEVEVFTLETDRKVCDIKILSVAPLKFDDINEFHAEQEAIELPKLKELIREIYPNINELYVIEYELIK
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: ASQE_EMENI
Sequence: MTQAPWSLARKTAIVTGGSRGIGRAIAIHLTCKGLSKLAITYISNLAAAESTLDECRKNGLGMGIAIKADLLDPNIGHGLVQQALAGLETPTIDILVNNAAYLDPSEAASVEELTLPVFQKVMQANAFAPISIISATMPHLPVSGGRVINISSAAAKLANPGPVMTYGASKAALDSFTRSLAAEFATDKAATFNTVCVGPTVTDGFHVVGKLYPEGFMEELAKAFTAAQRVGMPQDIAFIVGFLAGEEARWVNGACMSANGGFREVLPALS
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of the aspoquinolone mycotoxins (PubMed:25251934).  The role of asqE within the aspoquinolone pathway has still to be determined (Probable).  The first step of the pathway is catalyzed by the nonribosomal pepdide synthetase asqK that condenses anthranilic acid and O-methyl-L-tyrosine to produce 4'-methoxycyclopeptin.  4'-methoxycyclopeptin is then converted to 4'-methoxydehydrocyclopeptin by the ketoglutarate-dependent dioxygenase asqJ.  AsqJ also converts its first product 4'-methoxydehydrocyclopeptin to 4'-methoxycyclopenin.  The following conversion of 4'-methoxycyclopenin into 4'-methoxyviridicatin is catalyzed by the cyclopenase asqI.  4'-methoxyviridicatin is the precursor of quinolone natural products, and is further converted to quinolinone B.  The prenyltransferase asqH1 then catalyzes the canonical Friedel-Crafts alkylation of quinolinone B with dimethylallyl cation to yield dimethylallyl quinolone, which is subjected to FAD-dependent dehydrogenation by the FAD-linked oxidoreductase asqF to yield conjugated aryl diene.  The delta(3') double bond then serves as the site of the second alkylation with DMAPP catalyzed by the prenyltransferase asqH2 to yield a carbenium ion intermediate, which can be attacked by H(2)O to yield a styrenyl quinolone containing a C3'-hydroxyprenyl chain.  The FAD-dependent monooxygenase asqG performs epoxidation of the terminal C7'-C8' olefin.  Finally, after dehydratation of the epoxide at C3 by asqC, the quinolone epoxide rearrangement protein asqO catalyzes an enzymatic 3-exo-tet cyclization to yield the cyclopropyl-THF ring system in aspoquinolone (Probable).
What are the official names of this protein?
Short chain dehydrogenase asqE, 4'-methoxyviridicatin/aspoquinolone biosynthesis cluster protein asqE, Aspoquinolone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RNFA_PSEA7
Sequence: MTELALILVSAILVNNFVLVQFLGLCPFMGVSRKIETAIGLSLATTFVLTLAAICSYILQRYVLRPLDLEFLRTIGFILVIAVVVQFTEMLVKKTSPLLYRVLGIFLPLITTNCIVLGVALLNANRAEYGFLEATTQGFGAGLGFSLVLVLFAALRERIAIADVPAPFRGAAIGMITAGLMSLAFMGFSGLIRP
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATP6_SODGM
Sequence: MSASGEISTPQEYIGHHLNNLQLDMRTFELVNHHTASSFWVLNIDSMFFSLLLGAIFLLIFGRVAKGATSGVPGKMQTFVELVVGFVDGSVRDMFHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYLGEHVLGLPALRVVPSADVNITLSMALGVFILILYYSVMMKGIGGFVKELTLQPFNHPIFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLAMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VE1_HPV41
Sequence: MASRVSDTGNGNENKENEGTVASDHSEARCSYILFEAECSDGGDDEESMEDSLVEDLVDDASVHQGNSLSLFHAQTVEEYEGEIQSLKRKFILSPLHRDVAELSPRLAGVSLEENRGKKARKSLFHDDSGIDSSAVEVSQLSSTPSAPGPDIRLPKPSDIDLEPLFQSRQRCTHMYSKFKAVYGVSFTDITRPFKSDKTTSQHWVVAAYYLAFDSEISAMEVLLRQQCQFLYIDNNDGIILFFLEYNVQKSRTTVYNWFTANFHYNENRMLANPPRTRNMPAALFFYHRFMGTGGIKHGAMPEIIVNQCVVSNQQTDTFELSRMVQWALDNDLQDEHMLALEYALLAESDGNARAFLKQNNQPMIVKNCSIMVRHYKTALVAKMSISQYVNKRCLDHGEADENSWRGIVHFLRYQGQEFLPFMCKMHNFLHHRPKKSTLVLCGPSDTGKSYFANGLNKFLDGHVLSFVSNGSHFWLSPLRGARCCLIDDATLTFWRYADQNMRALLDGYEISIDAKHRNPMQTRAPPLIITTNEDIMRLDEFKYLQTRTMYVYFNKPFPLKGNGQPLYYIDGYTWNSFFRKFWRHLNLKDPEDESDGETPGTIRLYTRADTDTI
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: ACTP_ECOL5
Sequence: MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRNDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEP9_UNCRE
Sequence: MHGLLLAAGLLTLPLRALAHPGHQSTSILSRRGAVDLDAYRVSAKAEYSNVNDVAENPPAVSLMSSGSYVDIATELVKTTLPGVTFRVVNDHYVGTNGVAHVHFRQTIHGVDVDNADFNVNVKDGKVFSFGNGFYKGEIPKENPMVKRDFSDPVHALKGACNALKIPIKTNKVSVKSGKGQESVVFKGTSGALSEPKGDLVYFVKPDGKLSLTWRVETDVGDNWLSSYVDAKDSSKIHGVTDYVADATFQVYPWGLNDPTEGSRQTLTDPWERNASEFTWHSDGNTRYPTTRGNNGIAQDNPSGGTGYLNNYRPQSSALRFEYPYSTSMSPPTSYKDASITQLFYTANTFHDLTYLLGFTERAGNFEVNNNNQGGRGNDFVILNAQDGSGVNNANFATPPDGQPGRMRMYTWNRSQPNRDGCFEAGIVIHEYAHGLSNRLCGGPANSRCLSALESGGMGEGWGDFLATAIRLKANDTRRTSYTMGEWASNQRGGIRQYPYSTSTTTNPLVYTTVNRYNRVHDIGTVWATMLYEVLWNLIDKHGKNDGPRPEFRNGVPTDGKYLTMKLVIDGMALMPCNPNFVQARDAIIDADEALTGGQNKCEIWAGFAKRQLGTGARYGRTNRVGSTEVPSECR
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Extracellular metalloproteinase 9, Elastinolytic metalloproteinase MEP9, Fungalysin MEP9.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DFB40_MOUSE
Sequence: MKISCFLLMIFFLSCFQINPVAVLDTIKCLQGNNNCHIQKCPWFLLQVSTCYKGKGRCCQKRRWFARSHVYHV
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 40, BD-40, mBD-40, Defensin, beta 40.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1753_BURVG
Sequence: MLKGNLAGLMKQAQQMQENMKKMQEQLAQIEVEGQSGAGLVKVTMTCRNEVRRVAIDPSLLADDKDMLEDLVAAAFNDAVRKAEATSQEKMSGMTSGLPLPPGFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Bcep1808_1753.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MRAZ_LISMF
Sequence: MFMGEYQHNIDIKGRLIVPAKFRELLGDNFVITRGLDKCLFAYPQEEWKKLEEKLQTLPLTKKDARSFTRFFFSGASECELDKQGRINIPSNLLQYADLEKETVIIGVSSRIEIWSKSEWDDVFNEAEESFADLAENMIGFDI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CLE1_CONLT
Sequence: MKLSVMFIVFLMLTMPMTCAGISRSATNGGEADVRAHDKAANLMALLQERMCPPLCKPSCTNCG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (PubMed:16797781, PubMed:25617597).  This synthetic peptide displays analgesic activity in a hot plate assay (PubMed:16797781, PubMed:25617597, PubMed:21126549).  Analgesia is also observed against second phase pain in formalin-induced inflammatory pain model, and in a rat model of mechanically-induced pain (PubMed:25617597).  Effects downstream of nAChR are inhibition of calcium influx, inhibition of ERK1/2 phosphorylation and inhibition of c-fos/NOS expression (PubMed:25617597).  Genes associated with drug dependence are not up-regulated by this toxin (PubMed:25617597).  Treatment with this toxin reversed morphine withdrawal symptoms in mice (PubMed:25617597).
What are the official names of this protein?
Alpha-conotoxin Lt14.1, Alpha-L-conotoxin Lt14a, Alpha-conotoxin LtXIVA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin L superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: K2C1_RAT
Sequence: MSFQCSSRSLCRSGGGGGGRNFSSGSAGLVSFQRRSTSSSMRRSGGGGGGRFSGGGFCGSSGGGFGSKSLVNLGGGRSISISVAGGGSSYGGGFGGGSYGGGSFGGGSFGGGVGGGFGGGGFGGGGFGSGGGFGGGRFGGGFGPVCPPGGIQEVTINQSLLQPLNVEVDPQIQKVKSQEREQIKSLNDKFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTQNLDPFFESYISNLRRQVDSLKNDQSRMDSELKNMQDLVEEYRTKYEDEINKRTNAENEFVTIKKDVDSAYMNKAELQARVDNLQQDIDFFSTLYQMELSQMQTQISETNVVLSMDNNRTLDLDGIIAEVKAQYDSICQRSKAEAETFYQSKYEELQITAGKHGDSVKNTKMEISELNRVIQRLRSEIDSVKKQISQMQQNISDAEQRGEKALKDAQNKLNEIEDALTQAKEELTRLLRDYQELMNTKLALDMEIATYRKLLEGEEIRMSGECTPNVSVSVSTSHTSMSGTSSRGGGRYGSGGGGGGGTYGGGSRGGSYGGGSGGGSYGGCSSGGGSGGGSYGGGSSGGHRGGSGGGGGSSGGSYGGSSGGGRGGSSSGGGVKSSGSSSVKFVSTTYSRGTN
What is the function of this protein?
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1).  In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity).
What are the official names of this protein?
Keratin, type II cytoskeletal 1, Cytokeratin-1, CK-1, Keratin-1, K1, Type-II keratin Kb1.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm.
Protein: MDTA_ECODH
Sequence: MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSRSAAPGATKQAQQSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLIALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNEGHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVEAQSATTPEEKATSREYAKKGARS
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSTB_ALKEH
Sequence: MVSTMMNEQQQGGMTHGYNVEALKNKPKSKPGKATDTCLEVSDLQLWYGQDKVLKGVDMEIPRGRITAFIGPSGCGKSTLLRCFNRMNDLIDNCRIEGHIRIDGEDIYDRRVDIPELRRRVGMVFQKPNPFPKSIYENVAYGLRLQGVRNRRVLDEVVERSLKRAALWDEVKDRLHENALGLSGGQQQRLVIARAVAVEPEVLLLDEPASALDPLATLKIEELMFELKEEYTIAIVTHNMQQAARVSDYTAFMYLGELVEFNDTDTLFTTPAKKQTEDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IAPP_OCTDE
Sequence: MCLLQLPVVLLLLSAALNTLKATPIASDTDHRVDKRKCNTATCATQRLTNFLVRSSHNLGAALPPTKVGSNTYGRRNAEVVDVELLHYLPL
What is the function of this protein?
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
What are the official names of this protein?
Islet amyloid polypeptide, Amylin.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: U1SBP_RAT
Sequence: MSDWMPIAKEYDPLKAGSIDGTDEDPHDRAVWRAMLARYVPNKGVTGDPLLTLFVARLNSQTKEEKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEERALLKAYRDADGLVIDQHEIFVDYELERTLRGWIPRRLGGGLGGKKESGQLRFGGRDRPFRKPINLPVVKNEPHREGKRERRERSRSRDRHWDPRPRERDHDRGREKHWQDRARVWPENDWEREREFRDERAKTRDKRDRSK
What are the official names of this protein?
U11/U12 small nuclear ribonucleoprotein 35 kDa protein, U11/U12 snRNP 35 kDa protein, U1 snRNP-binding protein homolog.
What are the subcellular locations of this protein?
Nucleus.