PharMolix/UniProtQA huggingface dataset:
Protein: AROD_STAA8
Sequence: MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: GRC14_ORYSJ
Sequence: MDRVMKLASERAVVIFTLSSCCMCHTVTRLFCDLGVNALVHELDQDPRGKEMERALLKLLGRGPPVPVVFIGGKLVGGTNKIMSLHLGGELIPMLKNAGALWL
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins (By similarity).
What are the official names of this protein?
Putative glutaredoxin-C14.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KLRD1_BOVIN
Sequence: MAAFRTTAWRLISGVLGVICLVLMAALGVLLKNSLTKRSVQPGPSADLQEEYNLHEEEESCLGCLGSGCYSCQEKWIGYQCNCYFISNELKTWKDGRDFCVSHNSSLLQIQTRNEPAFMKFSTSFYWIGLSYDEEHHAWLWEDNSTLSQDLLPFFKSVNPKNCIMYNPRGRILDAYCEKKFRYICKQQLI
What is the function of this protein?
KLRD1-KLRC2 acts as an immune activating receptor.  On cytotoxic lymphocyte subsets recognizes MHC-E loaded with signal sequence-derived peptides from non-classical MHC class Ib MHC-G molecules, likely playing a role in the generation and effector functions of adaptive NK cells and in maternal-fetal tolerance during pregnancy.  Regulates the effector functions of terminally differentiated cytotoxic lymphocyte subsets, and in particular may play a role in adaptive NK cell response to viral infection.  Upon MHC-E-peptide binding, transmits intracellular signals via the adapter protein TYROBP/DAP12, triggering the phosphorylation of proximal signaling molecules and cell activation.
What are the official names of this protein?
Natural killer cells antigen CD94, Killer cell lectin-like receptor subfamily D member 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: CLP_TRYBB
Sequence: MAHSDRQCTNAAQTALSDAVESARKHNNGFVDPAHLALVLFKNEDGLASRVLRKLNAGTVLEPLAARVGALPEQRPRPRSITFSSDGGCAQHRRAEANRVGDSLIAVDHLLIGLFECKEVEAIMKAAHASKKAVEGALLELRKGKKVTSEFQEENYQALEKYATDLCKLAEEGKLDPVIGRTDEVLRTIRVLSRRTKNNPILIGEPGVGKTAIAEGIAQRIVRGDVPDTLLNTRLFSLDLGALIAGSSLRGEFEERLKSVLNEVKESSNGVILFIDEIHLVLGAGKSGGSMDAANLLKPMLARGELRTIGATTLEEYRTYVEKDAAFERRFMPVYVTEPSVEECISILRGLKDRYEAHHGVQITDNAVVVAAQLANRYITNRFMPDKAIDLIDEACANVRVQLSSRPEAIDILERKKRQLEIEAKALERDKEAASRERLKLVKADIQRVEEELQPLVSKYNDERQRIDELQEMQSRLDEKKKLERAVRDGKMDLAADLQYNVIPLIQDRIRSLKEDIERQKATLVQEKVTEGDVAAVVARWTGIPVVKLSQTDRERLLNLSMHLHRRVKGQDEAVERVADAIIRARAGLSRPNSPTASFLFLGPTGVGKTELVKAVAAELFDDEKHMVRIDMSEYMEQHSVSRLIGAPPGYIGHDEGGQLTEPVRRRPHAVVLFDEVEKAHPNVYNVLLQVLDDGRLTDSRGRTVDFSNTIIVMTSNLGSEHLLNPEETNESYEVLRENVLAAVRSYFRPELINRLDDIVVFRRLRTEDLRGVVDNLIAGVNERLKSSGFSVLLDDGVKDFILEHGHDANMGARPLRRWIEKNIVTEIGRMLIAKELPPNSTLRVSLPEGGNKLTFGVKRGLTSDEWE
What are the official names of this protein?
Heat shock protein 100, Protein CLP.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
Protein: CARD_MYCTU
Sequence: MIFKVGDTVVYPHHGAALVEAIETRTIKGEQKEYLVLKVAQGDLTVRVPAENAEYVGVRDVVGQEGLDKVFQVLRAPHTEEPTNWSRRYKANLEKLASGDVNKVAEVVRDLWRRDQERGLSAGEKRMLAKARQILVGELALAESTDDAKAETILDEVLAAAS
What is the function of this protein?
Controls rRNA transcription by binding to the RNA polymerase (RNAP).  Required for replication and persistence during infection of mice.
What are the official names of this protein?
RNA polymerase-binding transcription factor CarD.
What is the protein family that this protein belongs to?
Belongs to the CarD family.
Protein: C3H15_ORYSJ
Sequence: MADGGGGGEAGSGGSAPVCSFVRKPPKNIRKRPTAPAGSDDDDEDGSGAIAAARAKKAPSSTSKLFFSSADGSSEPRRFQYESSRTIQASTDSRATATLETETEFDRDARAIRERQLKQAEESLKKNPSAPASSSGSGSGEVYKGIHGYTDYKAGFRREHTVSSEKAGGSHGPLRASAHIRLSARFDYQPDICKDYKETGYCGYGDSCKFMHDRGDYKSGWQIEKEWEEAEKARKRRIAMGGDGSDYEAGEEDDDDDEEALPFACYICREPFVDPVVTKCKHYFCEHCALKHHSKNKKCFVCNKPTLGIFNAAQEIRKKMAQDKKQ
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 15, OsC3H15.
Protein: NGF_GORGO
Sequence: MSMLFYTLITAFLIGIQAELHSESNVPAGHTIPQAHWTKLQHSLDTALRRARSAPAAAIAARVAGQTRNITVDPRLFKKRRLRSPRVLFSTQPPPEAADTQDLDFEVGGAAPFNRTHRSKRSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKAVRRA
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity).  The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse.  In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro) (By similarity).  Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI (By similarity).  Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer.  The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Beta-nerve growth factor, Beta-NGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted. Endosome lumen. Note=ProNGF is endocytosed after binding to the cell surface receptor formed by SORT1 and NGFR.
Protein: TEX11_HUMAN
Sequence: MISAHCNLRLLCSSDSSASASQVAGTTEVVENLVTNDNSPNIPEAIDRLFSDIANINRESMAEITDIQIEEMAVNLWNWALTIGGGWLVNEEQKIRLHYVACKLLSMCEASFASEQSIQRLIMMNMRIGKEWLDAGNFLIADECFQAAVASLEQLYVKLIQRSSPEADLTMEKITVESDHFRVLSYQAESAVAQGDFQRASMCVLQCKDMLMRLPQMTSSLHHLCYNFGVETQKNNKYEESSFWLSQSYDIGKMDKKSTGPEMLAKVLRLLATNYLDWDDTKYYDKALNAVNLANKEHLSSPGLFLKMKILLKGETSNEELLEAVMEILHLDMPLDFCLNIAKLLMDHERESVGFHFLTIIHERFKSSENIGKVLILHTDMLLQRKEELLAKEKIEEIFLAHQTGRQLTAESMNWLHNILWRQAASSFEVQNYTDALQWYYYSLRFYSTDEMDLDFTKLQRNMACCYLNLQQLDKAKEAVAEAERHDPRNVFTQFYIFKIAVIEGNSERALQAIITLENILTDEESEDNDLVAERGSPTMLLSLAAQFALENGQQIVAEKALEYLAQHSEDQEQVLTAVKCLLRFLLPKIAEMPESEDKKKEMDRLLTCLNRAFVKLSQPFGEEALSLESRANEAQWFRKTAWNLAVQCDKDPVMMREFFILSYKMSQFCPSDQVILIARKTCLLMAVAVDLEQGRKASTAFEQTMFLSRALEEIQTCNDIHNFLKQTGTFSNDSCEKLLLLYEFEVRAKLNDPLLESFLESVWELPHLETKTFETIAIIAMEKPAHYPLIALKALKKALLLYKKEEPIDISQYSKCMHNLVNLSVPDGASNVELCPLEEVWGYFEDALSHISRTKDYPEMEILWLMVKSWNTGVLMFSRSKYASAEKWCGLALRFLNHLTSFKESYETQMNMLYSQLVEALSNNKGPVFHEHGYWSKSD
What is the function of this protein?
Regulator of crossing-over during meiosis.  Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers.
What are the official names of this protein?
Testis-expressed protein 11, Protein ZIP4 homolog, ZIP4H.
What is the protein family that this protein belongs to?
Belongs to the SPO22 family.
What are the subcellular locations of this protein?
Chromosome. Note=Forms arrays of discrete foci along synaptonemal complexes in spermatocytes and fetal oocytes.
Protein: KTU_HUMAN
Sequence: MAKAAASSSLEDLDLSGEEVQRLTSAFQDPEFRRMFSQYAEELTDPENRRRYEAEITALERERGVEVRFVHPEPGHVLRTSLDGARRCFVNVCSNALVGAPSSRPGSGGDRGAAPGSHWSLPYSLAPGREYAGRSSSRYMVYDVVFHPDALALARRHEGFRQMLDATALEAVEKQFGVKLDRRNAKTLKAKYKGTPEAAVLRTPLPGVIPARPDGEPKGPLPDFPYPYQYPAAPGPRAPSPPEAALQPAPTEPRYSVVQRHHVDLQDYRCSRDSAPSPVPHELVITIELPLLRSAEQAALEVTRKLLCLDSRKPDYRLRLSLPYPVDDGRGKAQFNKARRQLVVTLPVVLPAARREPAVAVAAAAPEESADRSGTDGQACASAREGEAGPARSRAEDGGHDTCVAGAAGSGVTTLGDPEVAPPPAAAGEERVPKPGEQDLSRHAGSPPGSVEEPSPGGENSPGGGGSPCLSSRSLAWGSSAGRESARGDSSVETREESEGTGGQRSACAMGGPGTKSGEPLCPPLLCNQDKETLTLLIQVPRIQPQSLQGDLNPLWYKLRFSAQDLVYSFFLQFAPENKLSTTEPVISISSNNAVIELAKSPESHGHWREWYYGVNNDSLEERLFVNEENVNEFLEEVLSSPFKQSMSLTPPLIEVLQVTDNKIQINAKLQECSNSDQLQGKEERVNEESHLTEKEYIEHCNTPTTDSDSSIAVKALQIDSFGLVTCFQQESLDVSQMILGKSQQPESKMQSEFIKEKSATCSNEEKDNLNESVITEEKETDGDHLSSLLNKTTVHNIPGFDSIKETNMQDGSVQVIKDHVTNCAFSFQNSLLYDLD
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle. Note=Localizes in the apical cytoplasm around the gamma-tubulin-positive pericentriolar region, not in the cilia.
Protein: TRUA_ACIAD
Sequence: MMQRYAVGIEFCGIRYRGWQTQQAGVPSIQETIEKVLSKIADEPIILHGAGRTDAGVHATNMVAHFDTNAIRPQRGWLMGANSQLPKDISIQWIKEMNTDFHARFKATARRYRYVVYNTLNRPALLHKQVTHVYQTLDVDKMMLAARKFEGTHNFETFRAASCQSSQPVRHLSHCRLTRHGRYLVLDIQADGFLHHMVRNIMGCLLEIGQGCYEIEHIDTMFAAQDRKAAGVTAPADGLYFIQAYYPEHFELPQHPLGPHWLNLPDEIPNI
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: HEM3_SALPC
Sequence: MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: AROD_STAA2
Sequence: MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIIKHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: PPIC_SALTY
Sequence: MAKMAAALHILVKEEKLALDLLEQIKNGGDFEKLAKKHSICPSGKKGGHLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRK
What is the function of this protein?
PPIases accelerate the folding of proteins.  It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase C, PPIase C, Parvulin, Rotamase C.
What is the protein family that this protein belongs to?
Belongs to the PpiC/parvulin rotamase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_PARMW
Sequence: MPKLKTRKAAAKRFKATGTGKFTRRRAFRNHLLDHKTPKQKRHLATKAVVHETDELRVVRMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GCH3_SULIN
Sequence: MKVLAIKLVDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYSTFPLQLRFDNFLMIVDGITNTQLIYMINDMQENLPVGIKTCLGYGKTPLEAQWNASVCLNNKEDKFKEYVDEKIAALHFDINFNTEALKYTSVYDSFLEITNIYVDLSRFLYKIGGILQYLGGDNYLGFVSTNSVNKVIEKFSDDNKIKVGIGIGQNARTAIKLATTSLEKIRNNREKTWHIEEEYH
What is the function of this protein?
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP.  Also has an independent pyrophosphate phosphohydrolase activity.
What are the official names of this protein?
GTP cyclohydrolase III.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GTP cyclohydrolase family.
Protein: ATG27_KLULA
Sequence: MKVLLATALVSLLPFSSAVECSKNEILNKYRVNEFSIGGVSVQDTPPSETKESWWLNICDEHDSKSSIPDQCNVKDIFCGVTSVALPGKESIVTKVMDFTSSVALEVKETAEALSIRLSGAAWGSHILNADIYLQCQEKGSGSLTESSWTDDQNVKLVFSGPFGCLKKGNDNKDGNGDDDNNDKDGDDSDKKPHDGDKNGSKPKGGAGLGSWLVWLFMYATIFALIYLVVTSYMNTRNGSFNDFREEFVDRSTTFATNLPQFAKEVAGKIVNSGSSSQRGGYSAV
What is the function of this protein?
Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling.  Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation.  Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity).
What are the official names of this protein?
Autophagy-related protein 27.
What is the protein family that this protein belongs to?
Belongs to the ATG27 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Mitochondrion membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass type I membrane protein. Note=Cycles among the pre-autophagosomal structure (PAS), mitochondria and Golgi.
Protein: MCAT_LACPN
Sequence: MFKHTRKLQYNAKPDRSDPIMARRLQESLGGQWGETTGMMSYLSQGWASTGAEKYKDLLLDTGTEEMAHVEMISTMIGYLLEDAPFGPEDLKRDPSLATTMAGMDPEHSLVHGLNASLNNPNGAAWNAGYVTSSGNLVADMRFNVVRESEARLQVSRLYSMTEDEGVRDMLKFLLARETQHQLQFMKAQEELEEKYGIIVPGDMKEIEHSEFSHVLMNFSDGDGSKAFEGQVAKDGEKFTYQENPEAMGGIPHIKPGDPRLHNHQG
What is the function of this protein?
Catalyzes the decomposition of hydrogen peroxide into water and oxygen.
What are the official names of this protein?
Manganese catalase, Pseudocatalase.
What is the protein family that this protein belongs to?
Belongs to the manganese catalase family.
Protein: COBQ_THEPX
Sequence: MALKLMIQGTASSVGKSLLVAAFCRIFKQDGYRVAPFKSQNMALNSYITDEGLEIGRAQAMQAEAAGVKPSYHMNPILLKPSSDKKSQVVLRGKVYKNMSAAEYHQFKPQLLKFIKEDFDFLASQNDIVVIEGAGSPAEINLRDRDVVNMGMAEMVNAPVLLVGDIDKGGVFASIAGTLLLLKENERNRIEGVLINKFRGDIEILKPGLEMLENIVHKKVLGVVPYMDVHIDEEDGATERFYRRSTEGDIEIAVINLPHISNFTDFEPLAKVPGVKLRYVNKGERIGDCDVVIIPGTKNTIGDLQALKGYRLDKEIFEMRKKGKFIVGICGGYQILGKVIKDPGRIESTTSEIEGLGLLDVETVIENEKTTTQIKAVIRNNLPSILSPLRNIAVEGYEIHMGKSRILGDCQPFSVITHRNGEKIEVYDGCISDDGKVFGTYIHGIFENREFVREFINIVRKSKGLSPIEEIIDYKEFKEREYDKLADIVRKSIDMKKVYEIMERYKD
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: Y4ON_SINFN
Sequence: MLSTRKQNWGEDRVMFYDAQGRLRSLPASWTDVNEADLFSQVAAGRSFSRPDDLSALASLIDRIKRRQEE
What are the official names of this protein?
Uncharacterized protein y4oN.
Protein: SUCA_HUMAN
Sequence: MTATLAAAADIATMVSGSSGLAAARLLSRSFLLPQNGIRHCSYTASRQHLYVDKNTKIICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGQTHLGLPVFNTVKEAKEQTGATASVIYVPPPFAAAAINEAIEAEIPLVVCITEGIPQQDMVRVKHKLLRQEKTRLIGPNCPGVINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFIDCLEIFLNDSATEGIILIGEIGGNAEENAAEFLKQHNSGPNSKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRKML
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
What are the official names of this protein?
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: C3HPD_HYPJQ
Sequence: MLPRNSHYKGTAYVHGKASGPLIASNLELSFWGGVDPQTSQVIDHHHPLSGEFLQDAILAIPSGRGSCSGSGVLLELLLSGKGPKALIFSRREDILTLGVVVAEEIFGRSIPVVVLAVTDFEELLAARYVAVNGGTVSTVQLGDAMHSPEDDSTEPLDTTLGLSIELSNKDYAFLSGAHGQAAQAAMRIILRMAAMEGARKLIDITQVHIDGCVYTGPASLKFAETLRDWGGKVVTPTTLNSIFVDQRRWRAQGVPSVFGEAAEKLATAYTDMGALPTYTCAPYLLPSAPKRGEQVAWAESNAVVYANSVLGAKTMKYPDFLDICIALTGRAPYGGLHIESNRSASLCVELPVLQKADIDDSFYPLLGYHVGRIAGSRIPVVVGVDVLRPSRDDLKAFGAAFATMASAPMFHIVGVTPEAATLQDAIGRREGVECIRLDVTELQTVWRTLNSAEDNSPVDLISLGNPHFSIAELRRLASLCRGRAKHDKVAVMVTCARATYGLADQAGLIEELHRFGVEVITDTCWCMIGEPVIPTTSRTIMTNSAKYAHYGPGLTGRRFYFGSLARCVDAACDGYFDTKMPGFISSCIPKGAGVR
What is the function of this protein?
Catalyzes the dehydration of cis-3-hydroxy-L-proline (c3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C).  No activity with L-proline, trans-4-hydroxy-L-proline (t4LHyp), cis-4-hydroxy-L-proline (c4LHyp), trans-3-hydroxy-L-proline (t3LHyp), D-proline, cis-4-hydroxy-D-proline (c4DHyp), trans-4-hydroxy-D-proline (t4DHyp) or L-serine as substrates.  Because of the low catalytic efficiency, C3LHyp is likely not a main physiological substrate of this enzyme in H. jecorina.
What are the official names of this protein?
Cis-3-hydroxy-L-proline dehydratase, c3LHyp dehydratase, c3LHypD, Aconitase X, AcnX, TrLhpI.
What is the protein family that this protein belongs to?
Belongs to the aconitase X family.
Protein: S35A4_BOVIN
Sequence: MSVEDGGVPGLGRPRKARWTLMLLLSTAMYGAHAPLLALCHVDGRVPFRPSSAVLLTELTKLLLCALSLLVGWQAWPQGTPPWRQAAPFALSALLYGANNNLVIYLQRYMDPSTYQVLSNLKIGSTALFYCLCLRHRLSARQGLALLLLMAAGACYAAGGLQDPGTTLPGPPSAAATSPMPLHITPLGLLLLILYCLISGLSSVYTELLMKRQRLPLALQNLFLYSFGVLLNLGLHAGGGPGPGLLEGFSGWMALVVLSQALNGLLMSAVMKHGSSITRLFVVSCSLVVNAVLSAALLRLQLTAAFFLATLLIGLAVRLYYGSR
What is the function of this protein?
Mediates the transport of CDP-ribitol (By similarity).  Does not exhibit CMP-sialic acid, UDP-galactose and UDP-N-acetylglucosamine transport activity (By similarity).
What are the official names of this protein?
Probable UDP-sugar transporter protein SLC35A4, Solute carrier family 35 member A4.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: COAX_XANC5
Sequence: MSEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGRIAYVASVAAPALTQPMIACLQERFTQVRIVRTTAECAGVRIAYADPSRFGVDRFLALLGARGDAPVLVAGVGTALTIDVLGADGLHHGGRIAASPTTMREALHARAVQLPASGGDYVELAIDTDDALTSGCDGAAVALIERSLQHAQRSLGVPVRLLVHGGGAPPLLPLLPDASFRAALVLDGLATWATAAASP
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_SPASP
Sequence: RFKKIRRLGALPGLTSKRPRSGSDLKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQILLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKNKQRSKALIQNFIASSPHQEELPNHLTIDPLQYKGLVNQIIDSKWIGLKIN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SURE_CLOK1
Sequence: MRLLLTNDDGIMAEGIQVLAKHFEKDNEVIIAAPDVQRSGSGHCITTVPGELIIQEVKLEGINSKAYSITGTPADCARLGVRKLGNNQIDMVISGINNGFNLGIDSLYSGTVSAAIEAAICETPSIAVSLDTKGGNYDYNIAAEYALEVFSIYKDKYKNKDENVVLSLNVPCLPREKIKGLKVCRVGFKYHLQEIYDKGEKTEELSYNYTDIYYVKRGYAALSPLHYDLTNYKILGDINNLFTEK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_XANOP
Sequence: MQPPAFYVTGTDTGIGKTMGSTALLHALRARGHTAVGMKPVASGCERTPQGWRNEDALALQAASNPQPAYATLNPYALPAPLAPELAAADVGVTLSLEPITQAFAQLRAQAEVVVVEGVGGWAAPLSATLDQADLVRALQLPVVLVVGVRLGCINHARLTAAAIAADGLQCIGWIANEVDPQMERVEENIGMLRQRLAMPCWGRIPWRPDAEAAAQAQGLQLPR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NARF_NEMVE
Sequence: MAAHFSGALQLTNLDDFITPSQECIKPVKIEKKPGAKGLAKIKIESDGSYVQLSEDGGKSKLQKAEITLNDCLACSGCITTAESVLITQQSQDELFKILDSNRKLVKEGKGDVQKLVVISISPQSRASIAAKFNLTINDAAKKLSAFFKQLGVHYVFDTTFARDFSLAESQREFVRRFRAYQQGDEGCTPMLASACPGWMCYAEKTHGDYILPYISSTKSPQQIMGSLVKDHLASVVGKSPDSVYHVCVMPCFDKKLEASRDDFYNDMYSTRDVDCVISTVEVETMIQDHCPDFNSIDPVELDKLYCSSDSGDFFGHSGGGSGGFLEHIFKYASRELFDEKVDVLTYKTLRNKDFREVTLQVDGKDVLKFAAAYGFRNIQNLVQKLKRGKSPYHFVEVMACPSGLKFLAQDLFGPTFYPTLEPRSLEKNVQQKNGVSCIFI
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins (By similarity).
What are the official names of this protein?
Probable cytosolic Fe-S cluster assembly factor v1g210509.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: GFRA4_MOUSE
Sequence: MAHCMESALLLLLLLGSASFTDGNRCVDAAEACTADERCQQLRSEYVARCLGRAAPGGRPGPGGCVRSRCRRALRRFFARGPPALTHALLFCGCEGSACAERRRQTFAPACAFSGPGLVPPSCLEPLERCERSRLCRPRLLAFQASCAPAPGSRDRCPEEGGPRCLRVYAGLIGTVVTPNYLDNVSARVAPWCGCAASGNRREECEAFRKLFTRNPCLDGAIQAFDSLQPSVLQDQTAGCCFPRVSWLYALTALALQALL
What is the function of this protein?
Receptor for persephin.  Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.  May be important in C-cell development and, in the postnatal development of the adrenal medulla.
What are the official names of this protein?
GDNF family receptor alpha-4, GDNF receptor alpha-4, GDNFR-alpha-4, GFR-alpha-4, Persephin receptor.
What is the protein family that this protein belongs to?
Belongs to the GDNFR family.
What are the subcellular locations of this protein?
[Isoform a1]: Cell membrane; Lipid-anchor, GPI- anchor. SUBCELLULAR LOCATION: [Isoform b1]: Cell membrane; Lipid-anchor, GPI- anchor. SUBCELLULAR LOCATION: [Isoform a3]: Secreted. SUBCELLULAR LOCATION: [Isoform b3]: Secreted.