PharMolix/UniProtQA huggingface dataset:
Protein: ENV_HV1B1
Sequence: MRVKEKYQHLWRWGWRWGTMLLGMLMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNDMVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTDLKNDTNTNSSSGRMIMEKGEIKNCSFNISTSIRGKVQKEYAFFYKLDIIPIDNDTTSYTLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSANFTDNAKTIIVQLNQSVEINCTRPNNNTRKSIRIQRGPGRAFVTIGKIGNMRQAHCNISRAKWNNTLKQIDSKLREQFGNNKTIIFKQSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWFNSTWSTKGSNNTEGSDTITLPCRIKQIINMWQEVGKAMYAPPISGQIRCSSNITGLLLTRDGGNSNNESEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGIGALFLGFLGAAGSTMGAASMTLTVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGIWGCSGKLICTTAVPWNASWSNKSLEQIWNNMTWMEWDREINNYTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWFNITNWLWYIKLFIMIVGGLVGLRIVFAVLSVVNRVRQGYSPLSFQTHLPIPRGPDRPEGIEEEGGERDRDRSIRLVNGSLALIWDDLRSLCLFSYHRLRDLLLIVTRIVELLGRRGWEALKYWWNLLQYWSQELKNSAVSLLNATAIAVAEGTDRVIEVVQGAYRAIRHIPRRIRQGLERILL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: ACPS_DESRM
Sequence: MKGIGTDIIEIERIELAVSRSGQQFLDRVFTAAEQEHCQGKVHSLAGRFAAKEAVLKALGTGLREMRWTNIEILPNHLGKPEVTLSGPALERAEKEGIHRILVSIAHDRGRAVAFAVAVGKEKEG
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_SHIDS
Sequence: MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF4A_ASPOR
Sequence: MSNDKGLEEIPEDQSTTPHKPTSNVGSRLTRLFQSTGQIETNYDEITDSFDAMELKPELLRGVYAYGFERPSAIQQRAIKPIIKGSDVIAQAQSGTGKTATFSISALQKLDPNVKGCQALILAPTRELAQQIQKVVVAIGDFMNITCHACIGGTAVREDMKALGEGPEVVVGTPGRVHDMIQRRVLKTDHLKQFILDEADEMLSRGFTEQIYDIFQLLPQSTQVVLLSATMPQDVLEVTTKFMRDPVRILVKKQELTLEGIKQFYIAVEKEEWKLDTLSDLYETVTITQAVIFCNTRRKVDWLTDKLTARDFTVSAMHGDMEQSQRDVIMKEFRSGSSRVLIATDLLARGIDVQQVSLVINYDLPANRENYIHRIGRGGRFGRKGVAINFVTADDVRMMREIEQFYSTQIEEMPMNVADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase eIF4A, Eukaryotic initiation factor 4A, eIF-4A, Translation initiation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_VESOH
Sequence: MKPIHTIHRRESKQIFVGNVAIGGDAPISVQSMTNTKTTDVKATLKQISEIEEAGADLVRVSIPTMEAARAFKVIKEQVTIPLIADIHFDYKIALEVAKYGADCLRINPGNIGRVDYISEVVASAKDHDIPIRIGVNAGSLEKYLQKKYTRPTPEAMVESALRHIDILDKLNFDNFKISLKASEIFMTVFAYQQLSSQIDNPLHLGITEAGSLSFGTVKSSIGLGLLLSKGIGDTIRVSLASDPVDEVRVAFNILKSLNLRQKGVNLIACPSCSRQKFDVIKVVSELESRFKDIITPIDVSVIGCVVNGPGEAKSVSVGLTGGDPNLLYLDGKTHSKIINENLVNELEAQVRNSLKNL
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: Y1253_CLOBB
Sequence: MKKFNKDIGTYCEKLSCDYLIEHNFKILECNFKNFLGEIDIICIKNSILIIIEVKGRYNYEFGLPKESVSISKQKNIIKVTKSYINYKKLYNFNVRFDVIEIYLNKLNSSYKINHIKDAFRT
What are the official names of this protein?
UPF0102 protein CLL_A1253.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: HIS4_BIFLD
Sequence: MSLTLLPAVDVRDGKAVRLRQGESGSETDYGSPFEAARTWVEAGAEWIHLVDLDAAFGTGNNRDQLREIVHELGDRVNIELSGGVRDDASLDAALEAGAARVNIGTAALENPDWTASVIKKYGDRVAVGLDVRGHTLAARGWTREGGDLFETMKFLDSVGCLRYVVTDVAKDGMMSGPNIQLLSEVAERTDAKVTASGGISKLDDLRAIKELAEIGVDSAILGKSLYARAFTLQEALEVAK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YF016_HUMAN
Sequence: MRLCLIPWNTTPHRVLPPVVWSAPSRKKPVLSARNSMMFGHLSPVRNPRLRGKFNLQLPSLDEQVIPTRLPKMEVRAEEPKEATEVKDQVETQGQEDNKTGPCSNGKAASTSRPLETQGNLTSSWYNPRPLEGNVHLKSLTEKNQTDKAQVHAVSFYSKGHGVTSSHSPAGGILPFGKPDPLPAVLPAPVPDCSLWPEKAALKVLGKDHLPSSPGLLMVGEDMQPKDPAALRSSRSSPPRAAGHRPRKRKLSGPPLQLQQTPPLQLRWDRDEGPPPAKLPCLSPEALLVGKASQREGRLQQGNMRKNVRVLSRTSKFRRLRQLLRRRKKRWQGRRGGSRL
What are the official names of this protein?
Putative UPF0607 protein ENSP00000332738.
What is the protein family that this protein belongs to?
Belongs to the UPF0607 family.
Protein: MPI2_ARATH
Sequence: MGADAIQTNGHDQAKLTGGEEIQRLRCFVKNYEWGKLGPESLVARLQEANTGQRVDSEIPYAEFWMGTHESGPSHVEFGSGHGVSDKCMVTLKSWVLDNPNLLGSKVVDKWGCDLPFLFKVLSVTKALSIQAHPNKALAEKLHREDPLLYRDNNHKPEIALAVTPFQALCGFVTLKELKEVITNVPEITELVGSKAADQIFNVHEHDEDERIKSVVRLIFTQLMSASNNETKQVVSRMKNRLLLETKHRELSEKEKLVLELEKQYTGDIGVISAFFFNYVKLNPGEALYLDANEPHAYISGDCVECMAASDNVVRAGLTPKHRDVQTLCSMLTYKLGYPEILKGFPLTPYVTRYLPPFDEFEVDHCDLPRGKSTVFPAVPGPSVYLVIEGKGQLRTGSSKVLVNRGDVLFVPADIEIHVTGESDVMKLYRAGVSSRFFQTL
What is the function of this protein?
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
What are the official names of this protein?
Mannose-6-phosphate isomerase 2, Phosphohexomutase 2, Phosphomannose isomerase 2, PMI2, Protein DARK INDUCIBLE 9.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 1 family.
Protein: STS1_ASHGO
Sequence: MSQSVGFEWGFKAGGEGRPRAQGDGAGCAGATAAANSQQGCGHLVHMSYKVGKPKMKRRLTNEEHGGARRAKRQPAQFNVIQGQPLPVHRKIEMMDKAALQLTLLQLVAMHPEVQDSLSVLQPTSPDPAKYTELLEQKMQAVYDHIPYSKSSDMLNDYAFVRMKAAILEFLNCLIDCLLDAIPPRTTNLLQSFKFLAYGTRLLAQMPHFETESNNYYKNICYEQVSEIWNTLIRHASSDINFLSTKPSLLHYLHELKQFNEQTKGKFDIPLRLFYTIMDDYHTQTVPAAAAVASTSATVAEELNGNSKSMETLGIWNNVA
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KAD_LACDB
Sequence: MINLILLGLPGAGKGTASEQIVDKYHLAHISTGDMFREAMANKTPVGLEAKSYIDKGDLVPDEVTAKLVEERLGQDDVKNGFILDGFPRTTNQAELLDEITTHLNKQLTNVIAIDVKEETLIDRLSARFMCKNCGATYNKFSKKPKVEGTCDRCGGHEFYQREDDKPEVVKNRLEVNEKMNAPLKEYYDKKGLLATVNGEQAPEKVFADIDAILSKD
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOJ_SHIFL
Sequence: MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFFSLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAIMLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGREERAGEVLSNRKDDSAKRKTEEHA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit J, NADH dehydrogenase I subunit J, NDH-1 subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FRDD_PECCP
Sequence: MINPTPKRSDEPPFWGLFGAGGMWSAFFAPVIILLVGIMLPLGLFPDALTYERIAAFSQSFIGRVFLLLMIVLPIWCGLHRIHHAMHDLKIHVPAGKWVFYGLAAILTVVTVIGVVTL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCD12_MOUSE
Sequence: MAAAPAGVGRLEEEALRRKERLKALREKTGRKDREDGEPQTKQLREEGEEVGKHRGLRLRNYVPEDEDLKRRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLEKRTQRAIAELIRERLKGQEDSLASAVDATTGQEACDSD
What are the official names of this protein?
Coiled-coil domain-containing protein 12.
Protein: MMPLB_MYCTO
Sequence: MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEVAGSQSLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDNAVALLRQIASELPGVTEAPNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVKGDQSGQTANGKVRLYVIGQGALSAAAAANTKHDIANAERWNLPIILMVLVAVFGSLAAAAIPLALAVCTVVITMGLVFVLSMHTTMSVFVTSTVSMFGIALAVDYSLFILMRYREELRCGRRPPDAVDAAMATSGLAVVLSGMTVIASLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFARAAAKRSALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPATLMVLGNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAGGASAPEHSQTIAAIRHRIAQAPNVVSVAPPRFADDNGSALLSAVLSVDPEDLGARDTITWMRTQLPRVAGAAQVDVGGPTALIKDFDDRVSATQPLVLVFVAVIAFLMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWARGLGFPALHSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGQTRDAVAYGVRTSARTITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATVVRLVLVPALMAMFDRWNWWLPRWLAHILPSVDFDRPLPKVDLGDVVVIPDDFAAAIPPSADVRMVLKSAAKLKRLAPDAICVTDPLAFTGCGCDGKALDQVQLAYRNGIARAISWGQRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRAGPGYRRRSPVETTNVALPTGDRLQIPTGAETLRFKGYLIMSRNSSHDYADFADLVDTMAPETAAAVLAGMDRYYSCQAPGRQWMATQLVGRLADPQPSDLGDQSPGADAQAKWEEVRRRCLSVAVAMLEEAR
What is the function of this protein?
Could also transport the mycolic acid-containing lipids monomeromycolyl diacylglycerol (MMDAG) and mycolate ester wax (WE) to the bacterial surface.
What are the official names of this protein?
Heme uptake protein MmpL11.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYA_STAAT
Sequence: MMKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAISGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQLKVKSDDQVVDKLTQLQDEEKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1103_LARHH
Sequence: MDAKLLEILVCPICKGPLVYKKEAGELVCKGDRLAFPVRDDIPVMLESDARELAADEDA
What are the official names of this protein?
UPF0434 protein LHK_01103.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: AROC_NEIMF
Sequence: MAGNTFGQLFTVTTFGESHGAGLGCIIDGCPPGLELSEADIQFDLDRRKPGTSRHVTQRRETDQVEILSGVFKGKTTGTPIALLIRNTDQRSKDYGNIAQSFRPGHADYTYWHKYGTRDYRGGGRSSARETAARVAAGAVAKKWLKEKFGTEITAYVTQVGEKEIRFEGCEHISQNPFFAANHSQIAELENYMDSVRKSLDSVGAKLHIEAANVPVGLGEPVFDRLDAEIAYAMMGINAVKGVEIGAGFDSVTQRGSEHGDELTPQGFLSNHSGGILGGISTGQDICVNIAIKPTSSIATPRRSIDINGNPIELATHGRHDPCVGLRAAPIAEAMLALVLIDHALRHRAQNADVAVDTPDIARSDK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SYI_ALIFM
Sequence: MSDYKDTLNLPETGFPMRGNLANREPEMLKRWYDEDLYGEIRKAKKGKKSFVLHDGPPYANGDIHIGHALNKILKDIIIKSKTLSGFDAPYVPGWDCHGLPIELMVEKKKGKPGQKISAAEFREECRKYAAGQVEGQKESFKRLGVMGEWDKPYRTMDFGTEANIIRSLGKIADQGHLLKGFKPVHWCTDCGSALAEAEVEYQDKVSPSIDVRFVAADEAATLAKFSTPEGHQGEGELSVVIWTTTPWTLPANRAVALHADLEYVLVQVEAHGEQKAQRLILASELAKSVLDRANIEHYHNLGFAKGSDLELLQFNHPFYNFTVPAILGEHVTTDSGTGIVHTAPGHGQEDFVVGKKYDLEIANPVGSNGVYLPDTELFAGQHVFKANDSVLEVLKEKGALLHHHAYEHSYPHCWRHKTPIIFRATPQWFISMDQAGLRAKALEEVKSVEWMPEWGQNRIEGMIEGRPEWCISRQRTWGVPIALFVHKETAELHPDSLELIEKVAKLVEEKGIQAWWDVDAAELMGEEDAANYEKVLDTLDVWFDSGVTHFSVVDSREEYNFPEEERTHSADLYLEGSDQHRGWFQSSLISSVAMKGKAPYRQVLTHGFVVDGNGRKMSKSIGNVVAPKDVTNKLGADILRLWVASTDYTNEVAVSDEILKRSADAYRRIRNTARFFLANLSGFNPATDIVPAEEMVALDRWAVGRAFAAQQEIIKSYDEYNLHEVTQRLMHFCSIEMGSFYLDVIKDRQYTAKKGGHAQRSCQTALYYIVEALVRWMAPIMSFTADEIWNEMPGEREKFVFTGEWYQGLFDLAEGEEFNNEFWTDIQAVRASVNKLLEAARGEKVIGGALQAEVTLYADDALIAKINKLEDELRFVLLTSAATVKPLSEKTESAKATELDGLFVDVVASEAAKCERCWHHVADVGTIEGHEEVCGRCVSNIDGEGEERKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAS4_YEAST
Sequence: MGIFQSIEEANNTSERLLRSEIKNSHGEFEKFDFDTEEYEINPKRKLRLVSRINPNAGHLRKSKSCFTVDEHVDETRCQKPVMKSPFMSNVDDEIKKKRETITKMTLEIEHHELSQNIRKPTDDLLPDSTYQPYHKKMLKQENRMIQSDIVNGENEADRLSLISDRLGMLNWEVTLQKVTKINDPTDENEMETKRYQTKELIDSMLHKFESMKKKSRNLARRPASSDSLLKLVSGKDWPKIYTRIDRTFIPDYASSSDEEEEKITVEEIRERRLKKREQQCGGSIIVLLSDHQSQKGMTRFAIVAEPLRKPYLIKTSTKERNSWKNKVPTNPKKFKKAPRISTQIAVKRRREVIPLTMEVEPEVIRDIRQDTQKSMKLNVKAEEISVTETVKSKEMNALRNNAASISPTLSEKAPLGSISSCTASQISQRSSENVGAIINNINPNLAIVPSCNEKTFVKTHNGMKTNSGINILPVRKKKKV
What is the function of this protein?
Component of the SAS complex, a multiprotein complex that acetylates 'Lys-16' of histone H4 and 'Lys-14' of histone H3.  The SAS complex is however unable to acetylate nucleosomal histones.  The complex is involved in transcriptional silencing at telomeres and at HML locus.  Also involved in rDNA silencing.  In the complex, SAS4 is essential for histone acetyltransferase (HAT) activity of the complex.
What are the official names of this protein?
Something about silencing protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUCC_SALPK
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVKSKEEIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIGKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: REPA_MSVS
Sequence: MASSSSNRQFSHRNANTFLTYPKCPENPEIACQMIWELVVRWIPKYILCAREAHKDGSLHLHALLQTEKPVRISDSRFFDINGFHPNIQSAKSVNRVRDYILKEPLAVFERGTFIPRKSPFLGKSDSEVKEKKPSKDEIMRDIISHATSKAEYLSMIQKELPFDWSTKLQYFEYSANKLFPEIQEEFTNPHPPSSPDLLCNESINDWLQPNIFQVSPEAYMLLQPTCYTLEDAISDLQWMDSVSSHQMKDQESRASTSSAQQEPENLLGPEA
What is the function of this protein?
Implicated in enhancement of V-sense gene expression.  Acts a an inhibitor of C-sense gene transcription (By similarity).
What are the official names of this protein?
Replication-associated protein A, RepA.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: GP4D_CHLTH
Sequence: MQNKSKVRDDFIKIVKDVKKDFPELDLKIRVNKEKVTFLNSPLELYHKSVSLILGLLQQIENSLGLFPDSPVLEKLEDNSLKLKKALIMLILSRKDMFSKAE
What are the official names of this protein?
Virulence plasmid protein pGP4-D, Protein P-8.
Protein: U71C5_ARATH
Sequence: MKTAELIFVPLPETGHLLSTIEFGKRLLNLDRRISMITILSMNLPYAPHADASLASLTASEPGIRIISLPEIHDPPPIKLLDTSSETYILDFIHKNIPCLRKTIQDLVSSSSSSGGGSSHVAGLILDFFCVGLIDIGREVNLPSYIFMTSNFGFLGVLQYLPERQRLTPSEFDESSGEEELHIPAFVNRVPAKVLPPGVFDKLSYGSLVKIGERLHEAKGILVNSFTQVEPYAAEHFSQGRDYPHVYPVGPVLNLTGRTNPGLASAQYKEMMKWLDEQPDSSVLFLCFGSMGVFPAPQITEIAHALELIGCRFIWAIRTNMAGDGDPQEPLPEGFVDRTMGRGIVCSWAPQVDILAHKATGGFVSHCGWNSVQESLWYGVPIATWPMYAEQQLNAFEMVKELGLAVEIRLDYVADGDRVTLEIVSADEIATAVRSLMDSDNPVRKKVIEKSSVARKAVGDGGSSTVATCNFIKDILGDHF
What is the function of this protein?
Possesses low quercetin 3-O-glucosyltransferase activity in vitro.
What are the official names of this protein?
UDP-glycosyltransferase 71C5.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: RL29_RHIWR
Sequence: MAKIADLTAKTDDQLAQDLGELKREQFNLRFQAATSQLEKPSRVKEVRRTIAQIKTLQTQRAAAAAK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: HMP_SALPA
Sequence: MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFNMSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGTHLLATLDEMFNPGQEVLDAWGKAYGVLANVFIHREAEIYHENASKDGGWEGTRPFRIVAKTPRSALITSFEFEPVDGGTVAEYRPGQYLGVWLKPEGFAHQEIRQYSLTRKPDGKGYRIAVKREDGGQVSNWLHHHASVGDVVHLAAPAGDFFMNVAADTPVSLISAGVGQTPMLAMLDTLAKEQHTAQVNWFHAAENGDVHAFADEVSELGRTLPRFTAHTWYREPTEADRAQRVFDSEGLMDLSQLEAAISDPAMQFYLCGPVGFMQFAAKQLVSLGVNNENIHYECFGPHKVL
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.