PharMolix/UniProtQA huggingface dataset:
Protein: OSGL1_MOUSE
Sequence: MLMLRRTAGAIPKPPKSKVYGFLRRFSVHPRTLSCHKLVLGIETSCDDTGAAVVDETGNVLGEALHSQTQVHLKTGGIVPPVAQQLHRENIQRIVEETLSACRITPSDLSAIATTIKPGLALSLGVGLSFSLQLVNQFKKPFIPIHHMEAHALTIRLTNKVEFPFLVLLISGGHCLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEQLAKDGNRFHFTINPPMQNAKNCDFSFTGLQHITDKLITHKEKEEGIEKGQILSSAADIAAAVQHATACHLAKRTHRAILFCKQKNLLSPANAVLVVSGGVASNLYIRKALEIVANATQCTLLCPPPRLCTDNGIMIAWNGIERLRAGLGVLHDVEDIRYEPKCPLGVDISREVAEAAIKVPRLKMAL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine.  Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  Involved in mitochondrial genome maintenance.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, O-sialoglycoprotein endopeptidase-like protein 1, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgepl1, tRNA threonylcarbamoyladenosine biosynthesis protein Osgepl1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ERA_CAMLR
Sequence: MKSGFVSIVGRTNAGKSSILNSLLEEKIAMVSHKQNATRRKINAIIMHEKNQVIFIDTPGLHASSKAINQLMIDLAIKSIADCDVILFVASIYDDIIDYENFLKLNPKVPHIVLINKVDLADKKTLLSKLAQYNQFSSYFSAIIPYSIKQKFHKKILLDELVKYLPEHPYYFDPEFITTTNEKDIYRDFILEAIYENLSDEIPYTTEVRIDKIKELKTIYYINATIISSTNSHKGMILGKDGATIKRIGKEARVKIEKLAQKKVMLKLFVQLEKNWHKNEQNLKKILYDE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: PYRG_BRUA4
Sequence: MARYVFITGGVVSSLGKGIAAAALAALLQARGYRVRIRKLDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRPANQQDNITTGRIYRNIIEKERRGDYLGATVQVIPHVTDEIKNFVLEGNEDYDFVLCEIGGTVGDIEAMPFLEAIRQLGNELPRGTAVYIHLTLMPYIPAAGELKTKPTQHSVKELRSIGIAPDILLVRADREIPESERRKLSLFCNVRESAVIQALDVATIYDVPIAYHKEGLDSEVLSAFGIDPAPKPRMDRWEEVSNRLHNPEGEVTIAIVGKYTGLKDAYKSLIEALYHGGLANKVKVNLDWIEAEVFESEDPAPYLEKVHGILVPGGFGERGAEGKILAAKFARERKVPYFGICFGMQMACIEAARNLVGIENASSTEFGPTKEPVVGLMTEWLKGNMLEKRASAGDLGGTMRLGAYEAALKSGSKIAEIYGSTDISERHRHRYEVNIDYKERLESAGLNFAGMSPDGVLPETVEYPDHPWFIGVQYHPELKSRPFEPHPLFASFIEAAIEQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DTD_PELPD
Sequence: MKAVIQRVCSASVVVEGEVVGEIGQGILVLLGVEKGDDEAKASWLAEKIISLRIFGDDSDKMNLSLRDVGGSLLAVSQFTLAGNCAKGRRPSFDSAAPPEEGRRLYDHFVQAVRAKGVATATGIFQADMRVSLVNDGPVTFILER
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC42_RAT
Sequence: MAYYLNSEAHLDPGPIYVRENGQLHMVSLALDGVKNSLQKPRPFRLFPKGFSVELCMNREDDTAQKEKTDHFIFTYTREGNLRYSAKSLFSLVLGFISDNVDHIDSLIGFPEQIAEKLFSAAEARQKFTEPGAGLRALQKFTEAYGSLVLCSLCLRNRYLVVAEKLEEIKSFRELTRLDLSCCWLGDEHELLEHLTNEALSSVTQLHLKDNCLSDAGIRKMTAPVRVLKRGLENLTLLDLSCNPEITDAGIGYLFSFRKLNCLDISGTGLKDIKAVKDKLRTHIGLVHSKVPLKEFDHSNCKTEGWADQIVLQWERVSVEAVRQRKDPEPRKAAQYFYQKRALTEASRKCPLAETHMNSSGKLQFYREKAPDCHEPLLSQESKKSKKRAFEESEQEQSSPQSAKQKCVCLAVEDWDLLNSY
What are the official names of this protein?
Leucine-rich repeat-containing protein 42.
What is the protein family that this protein belongs to?
Belongs to the LRRC42 family.
Protein: CLPP_STAAC
Sequence: MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRZCD_MYXXA
Sequence: MSLDTPNEKPAGKARARKAPASKAGATNAASTSSSTKAITDTLLTVLSGNLQARVPKELVGESGVELAHLLNQVLDQFAASEHRKHVAAQEIDQALDALIGLVREGDLSRWNTTTEDPQLGPLLEGFGKVIETLRTFVREINEAALRLSSSANQVLAASTQHETSSTEQAAAIHETTATMEELKHASAQIAENAGSVARVAEETLGAARAGRGAIGEFIQAMQQIRSDGVAVADSIAKLSKRVERIGTVVEVIDEIADRSDLLALNAALEGSRAGEAGKGFSIVAAEMRRLAENVLDSTKEIKNLITEIREATAAAAGAAEASKSATESGEKLGAVAAQAVEGILAGVQETSDAARVINLATQQQRTATEQVVASMAEIEDVTRQTTQASKQATGAAAELTQLAGRLAELIKRFKAD
What is the function of this protein?
Methyl-accepting taxis protein necessary for the proper aggregation of cells to form fruiting bodies.  Frz genes define a system of signal transduction analogous to the enterobacterial chemotaxis systems.
What are the official names of this protein?
Frizzy aggregation protein FrzCD.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSLCA_ORYSJ
Sequence: MAPWSGFWAASRPALAAAAAGGTPVVVKMDNPNWSISEIDADGGEFLAGGRRRGRGKNAKQITWVLLLKAHRAAGCLAWLASAAVALGAAARRRVAAGRTDDADAETPAPRSRLYAFIRASLLLSVFLLAVELAAHANGRGRVLAASVDSFHSSWVRFRAAYVAPPLQLLADACVVLFLVQSADRLVQCLGCLYIHLNRIKPKPISSPAAAAAALPDLEDPDAGDYYPMVLVQIPMCNEKEVYQQSIAAVCNLDWPRSNILVQVLDDSDDPITQSLIKEEVEKWRQNGARIVYRHRVLREGYKAGNLKSAMSCSYVKDYEYVAIFDADFQPYPDFLKRTVPHFKDNEELGLVQARWSFVNKDENLLTRLQNINLCFHFEVEQQVNGIFINFFGFNGTAGVWRIKALEDSGGWMERTTVEDMDIAVRAHLNGWKFVFLNDVECQCELPESYEAYRKQQHRWHSGPMQLFRLCLPDIIRCKIAFWKKANLIFLFFLLRKLILPFYSFTLFCIILPMTMFIPEAELPDWVVCYIPALMSFLNILPAPKSFPFIIPYLLFENTMSVTKFNAMISGLFQLGSAYEWVVTKKSGRSSEGDLIALAPKELKQQKILDLTAIKEQSMLKQSSPRNEAKKKYNRIYKKELALSLLLLTAAARSLLSKQGIHFYFLMFQGLSFLLVGLDLIGEDVK
What is the function of this protein?
Probable beta-1,4-glucan synthase rather involved in the synthesis of the xyloglucan backbone than cellulose.  Seems to work simultaneously with xyloglucan 6-xylosyltransferase.  Xyloglucan is a noncellulosic polysaccharides of plant cell wall and consists of a glucan backbone substituted by xylose, galactose and fucose (By similarity).
What are the official names of this protein?
Putative xyloglucan glycosyltransferase 10, Cellulose synthase-like protein C10, OsCslC10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like C subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: IMA8_HUMAN
Sequence: MPTLDAPEERRRKFKYRGKDVSLRRQQRMAVSLELRKAKKDEQTLKRRNITSFCPDTPSEKTAKGVAVSLTLGEIIKGVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEAGLIPRMVEFLKSSLYPCLQFEAAWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCEQAVWALGNIAGDGPEFRDNVITSNAIPHLLALISPTLPITFLRNITWTLSNLCRNKNPYPCDTAVKQILPALLHLLQHQDSEVLSDACWALSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLTPSLRTVGNIVTGTDEQTQMAIDAGMLNVLPQLLQHNKPSIQKEAAWALSNVAAGPCHHIQQLLAYDVLPPLVALLKNGEFKVQKEAVWMVANFATGATMDQLIQLVHSGVLEPLVNLLTAPDVKIVLIILDVISCILQAAEKRSEKENLCLLIEELGGIDRIEALQLHENRQIGQSALNIIEKHFGEEEDESQTLLSQVIDQDYEFIDYECLAKK
What is the function of this protein?
Functions in nuclear protein import.
What are the official names of this protein?
Importin subunit alpha-8, Karyopherin subunit alpha-7.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPD_RHIE6
Sequence: MSATDLASLEKTIEAAFDNRDNVNMSTKGEVRDAVEAALNLLDEGKARVAERGADGVWTVNQWLKKAVLLSFRLNDMEVVKGGSGNSTWWDKVPSKFENWGENQFRAAGFRAVPNCVVRRSAYIAANAILMPSFVNLGAYVGEGTMVDTWATVGSCAQIGKHVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIIREGSVLGMGVYIGKSTKIVDRATGEVMYGEVPPYSVVVAGSMASANATMANGLPAPHLYCAVIVKRVDEQTRSKTGINELLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_DESOH
Sequence: MSSFKEFYTTEVVPKLQETFGYKNVMQIPKLEKIVLNMGLGEAISNIKIIDSAVEELKLISGQQPVIRRARKSIAAFKLRQGMPVGCMVTLRHERMYDFFNKLVNIALPRVRDFRGISGQAFDGQGNYTLGVREQIIFPEIEYDKIDKIKGLNITIVTSVQKDDEARELLRLMGMPFKN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NQRA_ACTP2
Sequence: MITIKKGLDLPIAGTPAQVIHNGNTVNEVAMLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVVFTAPASGTVVTINRGEKRVLQSVVIKVEGDEQITFTRYEAAQLASLSAEQVKQNLIESGLWTAFRTRPFSKVPALDAIPSSIFVNAMDTNPLAADPEVVLKEYETDFKDGLTVLTRLFNGQKPVYLCKDADSNIPLSPAIEGITIKSFSGVHPAGLVGTHIHFVDPVGATKQVWHLNYQDVIAIGKLFTTGELFTDRIISLAGPQVKNPRLVRTRLGANLSQLTANELNAGENRVISGSVLSGATAAGPVDYLGRYALQVSVLAEGREKELFGWIMPGSDKFSITRTVLGHFGKKLFNFTTAVHGGERAMVPIGAYERVMPLDIIPTLLLRDLAAGDTDSAQNLGCLELDEEDLALCTYVCPGKNNYGPMLRAALEKIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: MURB_PSESM
Sequence: MTLHVQSAVSLRPFNTFGVDVQARLFAQARNDDEVREALAYSAEHDVPLLVIGGGSNLLLSGDVQALVLRMASRGIRIVREDCLEAIVEAEAGEPWHPFVQSCLELGLAGLENLSLIPGTVGAAPMQNIGAYGVEIKDVFHGLTALDRETGELREFALQDCAFGYRDSVFKHQPGRWLILRVRFKLSREANLHLEYGPVRQRLDQLGIDKPTPFDVSRAICAIRSEKLPDPAVLGNAGSFFKNPLVAAELYATIKSQHPGVVGYPQADGQVKLAAGWLIEQAGWKGYRDGDAGVHKLQSLVLVNYGHASGLQLLNLARRIQADIVERFGVELEMEPNLY
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WECF_ECO7I
Sequence: MTVLIHVLGSDIPHHNRTVLRFFNHALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPSQFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLELFSEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KERA_HUMAN
Sequence: MAGTICFIMWVLFITDTVWSRSVRQVYEVHDSDDWTIHDFECPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRLLQAVII
What is the function of this protein?
May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.
What are the official names of this protein?
Keratocan, KTN, Keratan sulfate proteoglycan keratocan.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CSPLB_SORBI
Sequence: MFGSDDSGCHVMDDDVAPPANGSKAVTLLLRLITLALALTSAVLMATASECTIYGLDGATATTVTFKDYQPFIYLVGSNIAATILEVAAIYVQVGKGDDVEDAPMIPRVVLVVVDVAVQMLLYSATGAVFAAVMAYGPQISACTGAAGHFCEQVQRSKIISLAASLSAVLAAVAKDVALPCSVWPHPSS
What are the official names of this protein?
CASP-like protein 1U2, SbCASPL1U2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAUB_RHILO
Sequence: MPHLVLDKISIHYDGQPAPAVERVSIDVAGDDFVVLVGRSGCGKTSLLNVAAGLVTPARGSATINGRPITAPGSDRAVVFQNDALFPWLTARENVAFALRLRGVRPAERARRADELLALVKLGDAGDKRIWELSGGMRQRVGLARALAAEPQFLLLDEPLGALDALTRERMQTTLLDLWTASHAGVLMVTHGIEEALVLATRIVVLAPGPGRVVRTFEPGFSRRYAAGEPIRAIKADPAFATARGELTDAIFEGETA
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PFDA_HALWD
Sequence: MMGGGQQQQLQQLSEELQAIDEEIDELREEVDDLQSEQTSIDEAMDAIQTLESGATVQVPLGGDAYVRAEIQDADEIIVGLGADFAAEQSADNAVESLSTKQDALDNRIESLRDDIDELETESSQLEQQAQQMQQQMQQQQMQQMQDQQPEDNE
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AK_RICCN
Sequence: MALIIQKFGGTSVANIDRIKKIVPIIKTEIAKNNQVIVVVSAMAGVTNQLVTLCNELSSLNNISQFAEYDVALSSGEIVTASLLALALQEEDIKARSFLAWQLPMLTDNNHSKALVESITTDLLEKYLQLNTIPIIAGFQGINKSNRLTTLGRGGSDTTAALIAAAMKADRCDIYTDVEGIFTADPRIIPNAKKIKEIDFLEMLELASSGAQVLHPRAGELVMRYKIDMRVLSTFSPDTEGTLITSKDKNMENGIINSITSNKNLLKISVKSMSLSFLQVANMITQNNNHIEFMQEIKNNEEYSFITNLTDKNNLQALLTNLKDDKQIQYFTFDTEIATISLIGYGIKNDCKLLETILSKLTNDNINVHMIQLSEVKITLFINDQDTEKTIFNLYNLFKIS
What are the official names of this protein?
Aspartokinase, Aspartate kinase.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: RSMI_XYLFA
Sequence: MSTPGTLHIVATPIGNLGDLSPRAQHILRTVTMICAEDTRHTRQLLAHFGIERPLLALHAHNEDTLAERIITRLISGASLALVSDAGTPLISDPGFLLVRAARAAGIRVTPVPGPSALIAALSVSGLPSNRFTFEGFLPAKPTARRDRLTHLAHEPRTLIFYEASHRIAECLTDLATIFGSMRAAVVARELTKIFETVLDGTLATLQTQVANDDNQRKGEFVIIVQGAADQDAAKITEGRRVYALLKEHLPPSSAAKLAAEITGAPRKALYGG
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPB_CLOBK
Sequence: MNKDHEEQLEINEVSQKNKYKSIIESLLFMSGEPINIKDLATILNCKQDKVSSLLNEMNNSYVGKDRGIKILIHNRAVQLVTKPENSIYVEKLLKTNVRQSLSQAALETLSIIAYKQPITRVAIDEIRGVKSDRAIYTLLEKNIIKECGRLDVPGKPILYGTTEEFLKFFGLDSIEAIPNLEDLLKEFSKEEN
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: GCSH_YERPY
Sequence: MSNVPTELKYALSHEWVRADGDGVYSVGITEHAQELLGDMVFVDLPEVGSDVSAGSDCAVAESVKAASDIYAPISGEIVAVNTELENSPELVNSAPYTDGWLFSIKAADESELDNLLDADAYLAAIEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: Y887_ALKCK
Sequence: MSYVEQYYESISRLLRQTVDEGEEVLGKAADIMVHAIKEGKSLYLFGASHAGIIAEDAFYRAGGLALFNPIFSPALMLNVEPITLTSKLERLEGYGTILLESKPVKQGDVLFIHSVSGRNPVAIDMAIAAKQKGMTVISLTNVSYSKSVESRHSSGKRLFEVSDLVMDNHGEPGDAAVSVKSLSQKVAPTSTIVGSFIIHSIVLKMIEQLEEAGREVPVFRSANLDGGDAYNEAMMERHKHQIHYM
What are the official names of this protein?
UPF0309 protein ABC0887.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.
Protein: SF3B6_HUMAN
Sequence: MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGINTDPPK
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643).  SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (PubMed:12234937).  Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing (PubMed:16432215).  Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively (PubMed:16432215).
What are the official names of this protein?
Splicing factor 3B subunit 6, Pre-mRNA branch site protein p14, SF3b 14 kDa subunit, SF3B14a, Spliceosome-associated protein, 14-kDa, Splicing factor 3b, subunit 6, 14kDa.
What is the protein family that this protein belongs to?
Belongs to the SF3B6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TNR6B_HUMAN
Sequence: MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI
What is the function of this protein?
Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs) (PubMed:16289642, PubMed:19167051, PubMed:19304925, PubMed:32354837).  Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins (PubMed:16289642, PubMed:19167051, PubMed:19304925, PubMed:32354837).  As scaffolding protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes (PubMed:21981923).
What are the official names of this protein?
Trinucleotide repeat-containing gene 6B protein.
What is the protein family that this protein belongs to?
Belongs to the GW182 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Mammalian P-bodies are also known as GW bodies (GWBs).
Protein: YNFB_ECOSM
Sequence: MKITLSKRIGLLAFLLPCALALSTTVHAETNKLVIESGDSAQSRQHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVITP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: TL1X_SPIOL
Sequence: AESKKGFLPVIDKKDGYTFLYPFGGQEVSI
What are the official names of this protein?
Thylakoid lumenal 17 kDa protein, P17.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.