PharMolix/UniProtQA huggingface dataset:
Protein: CAMP_PAPPA
Sequence: MKTQRDSPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQKSPEDCDFKEDGLVKRCVGTVILNQARDSFDISCDKDNRRFARLGNFFRKVKEKIGGGLKKVGQKIKDFLGNLVPRTAS
What is the function of this protein?
Exhibits antimicrobial activity against E. coli and B. megaterium (in vitro).
What are the official names of this protein?
Cathelicidin antimicrobial peptide.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR14_NICSY
Sequence: MARKSLIQREKKRQKLEQKYHSIRRSSKKEISKVPSLSDKWEIYGKLQSPPRNSAPTRLHRRCFLTGRPRANYRDFGLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BEL1_SFV3L
Sequence: MASWEKEKELAHLHQPEDDPLPDLSLLLDMDQFEPTEGPDSNPGAEKIYLQLQVAPGDPSEKTYKFGYEDKEAQNPDLKMRNWVPDPEKMSKWACARLILCGLYNAKKAKELLKMDYDIHWEQSKEDSQYFEIEYHCKMCMTVIHEPMPVSYDKKTGLWIKMGPLRGDIGSVVHTCRRHYERCMSALPSSGEPLKPRVRANPVRRYREKSLIVADRPKRSRWGVAPREQPNTSSGDAMALMPGPCGPFNMDPPGCLLERVPGSEPGTSEMALAMSGGPFWEQVYRDSISGPPTGPSEN
What is the function of this protein?
Transcriptional transactivator that activates the viral internal promoter (IP), thereby enhancing its own expression.  This transactivation is repressed by nuclear factor I.  Also transactivates the long terminal repeat (LTR) promoter, thereby inducing structural gene expression, initiating the late phase of infection.  It is therefore a key regulator of viral gene expression.  It directly binds to and activates DNA target sites of viral promoters and those of distinct cellular genes.  Required for viral replication (By similarity).
What are the official names of this protein?
Protein Bel-1, Transactivator of spumavirus, Tas, Transcriptional transactivator.
What are the subcellular locations of this protein?
Host nucleus.
Protein: SYY_MYCLE
Sequence: MSSSILNELGWRGLVAQSTDLDALADELRRGPMTVYAGFDPTAPSLHVGHLVPLLVLRRFQRAGHRPIVLAGGATGMIGDPRDIGERTLNEAYTVAEWAERIRGQLERFVEFDDVAKSRNGAIVVNNLEWTSPMSAIEFLRDVGKHFSINLMLDRDTIRRRLNGQGISYTEFSYMLLQANDYAELHQRHGCALQIGGSDQWGNIIAGVRLVRQKLGATVHALTVPLVTAADGAKLGKSTGGGSLWLDPEMTSPYAWYQYFINTSDADVIRYLRWFTFLLPEELVELEQTTVSRPQERAAQRRLATELTVLVHGAAATQAVEHASRALFGQGELARLDEATLATALRETVVAELKPGNPDGIVDLLVASGLSPSRGAARRTIDEGGVLVNNIRIQSEEWTPRTSDFLHGRWLVLRRGKRNIAGIERV
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJJY_ECO57
Sequence: MTKVRNCVLDALSINVNNIISLVVGTFPQDPTVSKTAVILTILTAT
What are the official names of this protein?
Uncharacterized protein YjjY.
Protein: ODD33_ORYSJ
Sequence: MGSDFKAIPLIDISPLVGKIDDPSMVNDEDLLQVVQMLDDACREAGFFYVKGHGIADSLMKQVRDVTQKFFQLPYEEKLKIKMTPQSGYRGYQRVGENITKGKPDMHEAIDCYTPIEPGKYGDLAKPMVGSNLWPKYPSNFDVLLENYISLLRDLSRKIMRGIALALGAPVDAFEGTTAGDPFWVCRLIGYPVSTDIPEEQRTDTGCGAHTDYGLLTLVNQDDDICALEVRNQSGEWIYAKPIPGTFVCNIGDMLKVWSNGIYQPTLHRVVNNSPRYRVSVAFFYESNFDAAVEPVEFCRERTGGVAKYEKVVYGEHLVQKVLTNFVM
What is the function of this protein?
Involved in melatonin degradation (PubMed:25728912).  Catalyzes the hydroxylation of melatonin to produce 2-hydroxymelatonin (PubMed:25728912).
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase 33, Melatonin 2-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGR2_EGGLE
Sequence: MEYGKCRGIERGMGRRDFLKAATLLGATAAGAGMLAGCAPKSASEAQAQTAPAATGGLDPADVDWKYETDVVIVGSGSGGTCAAIEAAEAGADVVVFEKDKAMYGGNSALCGGYMLAAGWSTQEEITGYAGDTGEAFANQMLRWSQGLGNQDMIREACLRSGEAVDWMMDTGRTYEGASPLPPVWSCGDTEADVVPRSVYNHNAYGATEGHMATLKKRAESLSNIEIEMGCEVAHILKNAEGSVIGVQLADGSFAKARKGVVMACASVDNNLEMSKDLGLMQNVWGLTLEGAGLLAPGNPDMDSNTGDGVRMLREIGAELCMQQAVCMNDSIYVGGISDWGMSEILGKDVNIHDSSNIDAILVDKTGRRFCQDDAEWGYVMHECAQAAWKQGFTPDDPTTGYIFYVYDATGAPFFEMKGHTPDTCDTTFSADSVDGLAEFIGCDPTALASEVERWNSFCEAGLDADFGRRANMAPIATPPFYCDVVRPGPMGTFAGAKSNVEAEIIGLDGNPIPRLYGAGCIIGGNVSGAFYFGCGWSITNTVVWGREAGRNVAALEPWE
What is the function of this protein?
Involved in the inactivation of the cardiac medication and plant natural product digoxin, thus decreasing drug efficacy and toxicity.  Catalyzes the reduction of the alpha,beta-unsaturated butyrolactone ring of digoxin to the inactive metabolite dihydrodigoxin.  Likely uses the cytochrome Cgr1 as the physiological electron donor, encoded by the adjacent gene in the locus.  Only reduces digoxin and other cardenolide toxins, such as digitoxin, digoxigenin, ouabain and ouabagenin.  Therefore is a specialized enzyme present in some gut bacteria E. lenta that protects their human host against ingested plant toxins.
What are the official names of this protein?
Digoxin reductase, Cardenolide reductase, Cardiac glycoside reductase operon protein 2.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side.
Protein: KV315_HUMAN
Sequence: MEAPAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSNLAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 3-15, Ig kappa chain V-III region CLL, Ig kappa chain V-III region POM.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: CEP1_VZVD
Sequence: MQRIRPYWIKFEQTGGAGMADGMSGINIPSILGCSVTIDNLLTRAEEGLDVSDVIEDLRIQAIPRFVCEAREVTGLKPRFLANSVVSLRVKPEHQETVLVVLNGDSSEVSCDRYYMECVTQPAFRGFIFSVLTAVEDRVYTVGVPPRLLIYRMTLFRPDNVLDFTLCVILMYLEGIGPSGASPSLFVQLSVYLRRVECQIGPLEKMRRFLYEGVLWLLNTLMYVVDNNPFTKTRVLPHYMFVKLLNPQPGTAPNIIKAIYSCGVGQRFDLPHGTPPCPDGVVQVPPGLLNGPLRDSEYQKSVYFWWLNRTMVTPKNVQLFETYKNSPRVVK
What is the function of this protein?
Plays a critical role in cytoplasmic virus egress.  Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.
What are the official names of this protein?
Cytoplasmic envelopment protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 1 family.
What are the subcellular locations of this protein?
Virion. Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein: VATB2_HORVU
Sequence: MAPEMEEGTLEIGMEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGTTRRGQVLEVDGEKAVVQVFEGTSGIDNKYTTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGISTIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEQSKHAAEGGEEDNFAIVFAAMGVNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRKGSITQIPILTMPNDDITHPTPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRRDHSDVSNQLYANYAIGKDVQAMKAVVGEEALSSEDLLYLEFLDKFERKFVAQGAYDTRNIFQSLDLAWTLLRIFPRELLHRIPAKTLDQFYSRDATH
What is the function of this protein?
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase subunit B 2, V-ATPase subunit B 2, Vacuolar proton pump subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: PCP_MOUSE
Sequence: MGCRALLLLSFLLLGAATTIPPRLKTLGSPHLSASPTPDPAVARKYSVLYFEQKVDHFGFADMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCGEFMKIVTNDFRKSGPYCSESIRKSWNVIDKLSGSGSGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSDTVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWILDFYSNIQ
What is the function of this protein?
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin.  This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH (By similarity).
What are the official names of this protein?
Lysosomal Pro-X carboxypeptidase, Proline carboxypeptidase, Prolylcarboxypeptidase, PRCP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S28 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: COXX_HALH5
Sequence: MNKPDTAIEAADVIEAEANASSTVVQQKSWKDYLTLAKTGIVTSNLITTFAGLFLAATYIGVSLSDYFLTIVWTMVGAALVMAGGCTLNNYIDRDIDHLMERTKDRPSVTGRFSGQHILWTGFVQSAAGIFFLLLTTPVAAVIGFIGLFVYVVLYSMWTKRTTTLNTIVGSISGAVPPLIGWSAIDGSLHSYAWLMFFIMFFWQPPHFLALAMKRVEEYRRAGIPMLPVVAGFEMTKRQMVIYVVALTIVSLMLYPFGIIYTTVAAILGVGWLALGIAGFKMKDDVKWARLMFVYSLNYLTILFVLMVVVHL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
Protein: PHNC_CAUVC
Sequence: MTSDPVLSIRAASKTFGSRRALDAVSLDVNRGEMIALIGPSGSGKSTLLRSIDGLQTIDEGEGAITAFGGPVQARGKVSDQVRKARVRIGFIAQQFNLVGRLSLFSNVALGSLGRIPVVQGLLGWWPKETRDATMAALHRVGVSEYAAQRANTLSGGQQQRGAIARALVQKAKIILADEPVASLDPVSARKVMEILRDLNQSDGLTVVVTLHQVDYALRYCDRVVALKAGQKVYDGPASELKREKLIDIYGPEFEDVFWEGAPQ
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AN36A_HUMAN
Sequence: MEDGKRERWPTLMERLCSDGFAFPQYPIKPYHLKRIHRAVLHGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYERKRYEDLPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES
What are the official names of this protein?
Ankyrin repeat domain-containing protein 36A.
What is the protein family that this protein belongs to?
Belongs to the ANKRD36 family.
Protein: ANR49_HUMAN
Sequence: MEKEKGNDDGIPDQENSLDFSEHFNQLELLETHGHLIPTGTQSLWVGNSDEDEEQDDKNEEWYRLQEKKMEKDPSRLLLWAAEKNRLTTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGHLDIVQELIAQGADVHAVTVDGWTPLHSACKWNNTRVASFLLQHDADINAQTKGLLTPLHLAAGNRDSKDTLELLLMNRYVKPGLKNNLEETAFDIARRTSIYHYLFEIVEGCTNSSPQS
What is the function of this protein?
Induces HBG1 expression (PubMed:16131492, PubMed:11162141).  May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway (By similarity).
What are the official names of this protein?
Ankyrin repeat domain-containing protein 49, Fetal globin-inducing factor.
What are the subcellular locations of this protein?
Nucleus.
Protein: VA003_VACCW
Sequence: MDSLRPVVVVNWIQINFHIDIVKGITGYGFAFICGRDGVRICSETTRRTDDVSGYSVSYSTFCLGNTCLASG
What are the official names of this protein?
Uncharacterized protein VACWR003.
Protein: Y2005_STAAN
Sequence: MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITAVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILRHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDSRILEALVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
What are the official names of this protein?
Uncharacterized hydrolase SA2005.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: YBBH_BACSU
Sequence: MATGGLAIIQSMKHKLPPSERKLADYILAHPHKAIESTVNEISALANSSDAAVIRLCKSLGLKGFQDLKMRVAGDLAKPTFQGYRDIVPHEPLPSISEKTAGNAIQAIQDTSDLMDYKELERAVSLLLKAHTVHFIGLGASGIVAKDAQQKWLRIHKQATAFTDTHLVASLIANADKDDIVFAISFSGETQEIVELFAMAKEKGITTISLTQFSQTSVSALADVPLYTAHSNEALIRSAATSSRLAQLFIIDVLFLGMAAEQYETTTGYIDKTRAAIQSMRIK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YbbH.
Protein: UPPP_CHRSD
Sequence: MDWLHVVALAVIQGLTEFLPISSSAHLILPSQLLGWPDQGLAFDVAVHVGSLAAVVLAFHREVAHILRDWVAQCRGGPATPESRLGWAVIVGTLPAVVIGFLLENVIESYLRASLVIAITTLLFGLLLWWADVRGSRRHALTAMTLRNALIIGFAQALALIPGTSRSGITITAALLLGFTRQAAARFSFLLSIPLILAAGSLKGVELIESGEGVAWGTLVAGTLMSFVAAWLCIKLFLAALDRIGMLPFVIYRLILGIVLLVWVA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VFD29_ASFP4
Sequence: MDINPLLYLQAFNNDATTFNTQGHILEQQSDSPYFDTFANAMQAYLDTKQGGNDEEGTIILMDDEDFNDSESLEDFLQMLNEEELNDGFSSDDEPEEHVILTEDNQGEPSETPQATFDITEFIKTEDED
What are the official names of this protein?
Uncharacterized protein D129L, pD129L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus D129L family.
Protein: ATP6_DEBHA
Sequence: MIYSPTEQFEIKPLLTVNNMLTLSVNNYVMYVALVVTLMYSSVFLLNRTYLGFNRWGVALLAVYDTILNMVKSQMGARGGMYFPFMFTLFTFMLVANLVSMMPYSFAMSAQLVAIVSFSLSLWFGCVLMGLSKHGWGFFALFVPGGTPLALVPVLVLIETLSYSSRAISLGLRLSANVLSGHLLMLILGTLMFNLMGSSMLGFMGGFMPVMGVIAIVVTEFAIGMMQAYVFTILLSSYIKDSVYLH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane (By similarity).
What are the official names of this protein?
ATP synthase subunit a, ATP synthase subunit 6, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DEFA9_MOUSE
Sequence: MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSVSFGDPEGSSLQEESLRDLVCYCRKRGCKRREHMNGTCRKGHLLYMLCCR
What is the function of this protein?
Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
What are the official names of this protein?
Alpha-defensin 9, Defensin-related cryptdin-9.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURE_GLOVI
Sequence: MPAMRLHELLARTGLDTRNLPDIDIAGLSTDSRQVQPGDLFIGLPGTRVDGSEFWPQAIAGGAAGLVISENARGVEAAVPVIRVPDVVGTCARLASAYYDFPARKLTLAGVTGTNGKTTTTHLIENLLQAQAPTGLVGTLYSRWPGQSQEARHTTPFALEIQKLLAQMVEAGCQYGVMEVSSHALAQQRVAGCRFEAAVFTNLTQDHLDFHPDMESYFQAKATLFSPEYRSGRAVINADDPWGVRLAAAYDQVWTYSFQPGADIYPEDAVFTPEGIRGTLVTPVGRAAFTSPLVGQFNLANLLAAVGATLALGIDLEAIAAGLSGFGGVPGRMERVSGSDDDIAVIVDYAHTPDGLRKLLEATRPFVRGRLICVFGCGGDRDRTKRPQMGRIAAELSDLPVVTSDNPRTENPEAILDDILAGIPVGVSPTVEVDRRRAILQALLEAKAGDCVVIAGKGHEDYQILGTTKIHFDDREQAREALSKRRSRG
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IZH2_YEAST
Sequence: MSTLLERTKSVQELKKRAAGKTSANPAEVAKAKKVLRRLYSWDEIPEWQRDNDFILHGYVKETSSFIETFKSLFYLHNESVNIYSHLIPALGFFTVLLLDKSTIKVFATTTWLDHMVIDLFYSGAFACLILSSSFHCLKSHSLRIATLGNKLDYLGICILIVTSMVSILYYGYFEKFSLFCLFALITVSFGIACSIVSLKDKFRKREWRPYRAGLFVCFGLSSIIPIFSGLYCYSFSEIWTQIQLFWVLLGGVLYIIGAVLYGMRFPEKICPGKFDIWGHSHQLFHFLVVIAALCHLRGLLNSYELVHIKMENGIVS
What is the function of this protein?
Probable receptor, which is involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation.
What are the official names of this protein?
ADIPOR-like receptor IZH2, Phosphate metabolism protein 36.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: THIC_CLOPE
Sequence: MNYTTQMDAAKKGIITKEMQVVSEKEGINIETLMNLMAEGKIVIPANKNHKSISAEGVGQGLRTKINVNLGISKDCANIELELEKVKKAIDMNAESIMDLSNYGKTYDFRKRLVEVSTAMIGTVPMYDVVGFYDKELKDITVDEFFEVVEKHAKDGVDFVTIHAGLNRETIETFRRNKRLTNIVSRGGSLLFAWMELNNRENPFYEYFDRLLDICEKYDLTLSLGDACRPGSIADATDAVQIKELITLGELTKRAWERNVQVIIEGPGHMAMNEIEANVLLEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAMAASYGADFLCYVTPAEHLRLPNLEDVREGIVATKIAAHAADIAKGISGARDIDNKMSDARKRLDWDEMFSLAIDSEKAIRYRKESTPEHKDSCTMCGKMCSIRNMNKILEGKDINLLRED
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: HEMA_I64A6
Sequence: MNTQILILATSAFLCVRADKICLGHHAASNGTKVDTLTEKGIEVVNATETVEQKNIPKICSKGKQTIDLGQCGLLGTIIGPPQCDQFLEFSANLIIERREGNDICYPGKFDDEETLRQILRKSGGIKKENMGFTYTGVRTNGETSACRRSRSSFYAEMKWLLSNTDNGVFPQMTKSYKNTKREPALIIWGIHHSGSTAEQTRLYGSGNKLITVWSSKYQQSFAPNPGPRPQINGQSGRIDFYWLMLDPNDTVNFSFNGAFIAPDRASFLRGKSLGIQSDAQLDNNCEGECYHIGGTIISNLPFQNINSRAIGKCPRYVKQKSLMLATGMKNVPENSTHKQLTHHMRKKRGLFGAIAGFIENGWEGLIDGWYGYRHQNAQGEGTAADYKSTQSAINQITGKLNRLIEKTNQQFELIDNEFNEIEKQIGNVINWTRDSIIEIWSYNAEFLVAVENQHTIDLTDSEMNKLYEKVRRQLRENAEEDGNGCFEIFHQCDNDCMASIRNNTYDHKKYRKEAIQNRIQIDAVKLSSGYKDVILWFSFGASCFLFLAITMGLAFICIKNGNMRCTICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: DF274_ARATH
Sequence: MASSRFQLVALLVVFSLVISITANSVEKDVMDGPCRLRGTCNNDGDCDKHCHRSTDAAAMDGHCLFDKPTGPVCCCLFD
What are the official names of this protein?
Putative defensin-like protein 274.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.