PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_NOCFA
Sequence: MARAVGIDLGTTNSVVAVLEGGEPVVVANSEGSRTTPSIVAFAKNGEVLVGQPAKNQAVTNVDRTIRSVKRHIGTDWTVEIDGKKYTPQEISARTLMKLKRDAEAYLGEEITDAVITVPAYFEDAQRQATKEAGQIAGLNVLRIVNEPTAAALAYGLDKGDKEQTILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDQRIVNWLVDKFKASSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLSRAEFQKITSDLLDRTRAPFQQVIKDAGISVSDIDHVVLVGGSTRMPAVSDLVRELTGGKEPNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGVMTKLIERNTTIPTKRSETFTTADDNQPSVQIQVFQGEREIAAHNKLLGSFELTGIPPAPRGVPQIEVTFDIDANGIVHVTAKDKGTGKENTIKIQDGSGLSKEEIDRMIKDAEQHAAEDKARREEAETRNQAETLVHQTEKFIKDNEDKVPADVKSKVEAAIAEANEALAGTDIAAVKAAVEKLATESQALGQAIYEAQGADAAASSNGAASSANDDQVVDAEVVDEPVDTEKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MUTS_XANC8
Sequence: MQTADTKDKTKLSTGAAEHTPLMKQFFAAKSDYPDLLLFFRMGDFYELFYDDARKAARLLDITLTQRGSSGGAPIPMAGVPVHAYEGYLARLVALGESVAICEQIGDPALAKGLVERKVVRIVTPGTVTDEALLDERRDTLLMAISRSKQGYGLAWADLAGGRFLVNEVDSVDALEAEIARLEPAELLVPDEDNWPEFLRGRVGVRRRPPWLFDADSGRRQLLAFFKLHDLSGFGIDDKPCATAAAGALLGYVEETQKQRLPHLTSIAMEVASEAISMNAATRRHLELDTRVDGDTRNTLLGVLDSTVTPMGGRLLRRWLHRPLRLREVLVQRHHAVGSLIDTGADTDVREAFRALGDLERILTRVALRSARPRDFSTLRDGLALLPKVRTILAPLDSPRLQTLYAELGEHDATAHLLISAVAEQPPLKFSDGGVIATGYDADLDELRRLSTNADQFLIDLEQRERASSGIATLKVGYNRVHGYYIEISKGQAEKAPLHYSRRQTLTNAERYITEELKSFEDKVLSARERSLSREKLLYEGLLDALGGELEGLKRCASALSELDVLAGFAERAQALDWSQPELESAPCLHIERGRHPVVEAVRDQPFEPNDLDLHPDRRMLVITGPNMGGKSTYMRQNALIVLLAHIGSYVPASRAVIGPIDRILTRIGAGDDLARGQSTFMVEMAETSYILHHATPQSLVLMDEIGRGTSTYDGLALADAVARHLAHTNRCYTLFATHYFELTALADASHAGGGSGIANVHLDAVEHGERLVFMHAVKDGPANRSFGLQVAALAGLPKAAVQQARRRLAELEQRGGDSHAAEMAPAALDAPQQFGLFTAPSSAAQEALQALDPDELTPKQALEALYRLKALL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: YAAO_BACSU
Sequence: MNTPLYKALIQHARRNSHSFHVPGHHNGDVFFDDAKSIFDPLLTIDVTELAGLDDLHHPSGVIKEAQELASQLYGSAESFFLVNGTTVGNLAMILSVCEPGDTILVQRNCHKSVFHAVDLSGAEPVYLAPDVDSAMHVPTHVPLGTIKEALEAYPDAKGLVLTNPTYYGHSADLTEIITEAHHYGIPVLVDEAHGAHFILGEPFPVSALKMGADIVVQSAHKTLPAMTMGSYLHLNSSCRINRDRVAEYLNRLQSSSPSYPIMASLDIARAYVQHIIEEQKLSDILQRIETLKQTFDSLTNAEAVNPANPLIITDPLKLTIRSKRGHSGYTLQSILERANIFTELADENQVLLVLPLGGKRRINAEIIRSIDEEIEKTPPDQTFVSAEWGVQPVTVLPYPKKVLHSFKKEYVSFEEAAGRLNAEDIIPYPPGIPMIMAGERITKESVQKLSRLISMKTHVQGNMKIKEKQLLVYIEEEKS
What are the official names of this protein?
Uncharacterized protein YaaO.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-I family.
Protein: RNPA_ERWT9
Sequence: MVKLAFPRELRLLTPTHFTFVFQQPQRAGTPQITILGRLNALGHPRIGLTVAKKHVKRAHERNRIKRLTRESFRLRQHELPAMDFVIVAKKGIGELDNHALTEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: KEFB_ENT38
Sequence: MEGTDLLLAGVLFLFAAVVAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPAKLWQLRRSIFGVGAAQVLFSAVILGGLLMLTQFKWQAAVIGGIGLAMSSTAMALQLMRDKGMNRNESGQLGFSVLLFQDLAVIPALALVPLLAGSGDDHFDWMKVGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGILLAESEYRHELEIAIDPFKGLLLGLFFISVGMALNLGVLYTHLLWVVVSVAVLVAVKTGVLYTLARIYGLRSSERMQFAGVLSQGGEFAFVLFSTAASQRLFQDDQMALLLVTVTLSMMTTPLLMKLIDKLLSRRFNQPDDEDEAPWVEDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQLELLRSAGAEAAESIIITCNEPEDTMKLVELCQQHFPHLHILARARGRVEAHELLQAGVTNFSRETFSSALELGRKALVSLGMHPHQAQRAQMHFRRLDMRMLRELMPVHSDTAQISRVREARRELEEIFQREMQQERRQFDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BC1_ORYSJ
Sequence: MAGFSHLPQQMEHGLITNNGFLFCHGSHGGAATTTAPAIPEDASMETSSVVLDTSPQDKKRKPREEDTASLNSAHSKEAKENGRKRGGKKHSRDQMEEEAPQGFIHVRARRGQATDSHSLAERVRRERISERMRMLQALVPGCDKVTGKALILDEIINYVQSLQNQVEFLSMRIASLSPVLYGFGIDSDAFSDHSQKMEGMFHEAVAIPASVLNRGSSPAQSHAIMDTSNTSPTPYTLQVQGGSNNNSLSQDNGSYIMQTVGEPRQELFNQVVLNNYMCSFQ
What is the function of this protein?
Transcription activator that contributes, together with LO9-177 and ILI5/BUL1, to the promotion of leaf inclination and grain size by modulating cell elongation (PubMed:27879391).  Involved in the RLI1-dependent modulation of leaf inclination by promoting lamina joint cell elongation, especially in response to phosphate (Pi) availability (PubMed:29610209).
What are the official names of this protein?
Transcription factor BC1, Basic helix-loop-helix protein 81, OsbHLH081, Protein BU1-LIKE 1 COMPLEX 1, OsBC1.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
Protein: UD16_HUMAN
Sequence: MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTAPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
What is the function of this protein?
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.  This isoform has specificity for phenols.  Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity).
What are the official names of this protein?
UDP-glucuronosyltransferase 1-6, UDPGT 1-6, UGT1*6, UGT1-06, UGT1.6, Phenol-metabolizing UDP-glucuronosyltransferase, UDP-glucuronosyltransferase 1-F, UGT-1F, UGT1F, UDP-glucuronosyltransferase 1A6.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: DR102_ARATH
Sequence: MAGAVSAVDQPLKIITGADDFGASLKDAMVTHLRSLGIDVEDTGVSSYYSAGSEVGRRVSASSSSEVRGLVCCGTGVGVAMFANKFPGVYAATCLSVEDAVNARSISNCNVLAFSGIKTSPETALEIFDAWIKTPFKSPCPASGSEPWSSVISSFLDNSLSEMSQIGKSTAGDSTTKKIDETTASCVICCLAKNREFTPVDIMPGGSMKIVRETPTSAIVRFKAGSVEPAHHHTFGHDLVVIKGKKSVWNLSKKERADLVDGDYLFTPAGDVHRVKYHEDTEFFITWDGHWDIFLDEDLETAKKAIEEEA
What are the official names of this protein?
DNA damage-repair/toleration protein DRT102.
Protein: VME1_IBVG
Sequence: MAENCTLDSEQAVLLFKEYNLFITAFLLFLTILLQYGYATRSRTIYILKMIVLWCFWPLNIAVGVISCIYPPNTGGLVAAIILTVFACLSFVGYWIQSCRLFKRCRSWWSFNPESNAVGSILLTNGQQCNFAIESVPMVLAPIIKNGVLYCEGQWLAKCEPDHLPKDIFVCTPDRRNIYRMVQKYTGDQSGNKKRFATFVYAKQSVDTGELESVATGGSSLYT
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the gammacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: PGAP2_BOVIN
Sequence: MYQVPLPLDRDGTLVRLRFTLVALVTVCCPLVAFLFCVLWSLLFHFKETTATHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLVAFAYWNHYLSCTSPCAGYRPLCRLNFGLNVVENVALLVLTYVSSSEDFTIHENAFIVFIASSLSHMLLTCILWRLTKKHTVSQEDRKSYNWKQRLFIINFVSFFTALAVYFRHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITSQPEEKRF
What is the function of this protein?
Involved in the lipid remodeling steps of GPI-anchor maturation.  Required for stable expression of GPI-anchored proteins at the cell surface (By similarity).
What are the official names of this protein?
Post-GPI attachment to proteins factor 2.
What is the protein family that this protein belongs to?
Belongs to the PGAP2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SK1_SYMPA
Sequence: EQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, SymPa-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRE_NOSS1
Sequence: MTYSTESLAQSDIWPATADVSTLRRKLLDLLCQLAYKEGDFVLSSGQPSSYYINGKQVTLHPQGALAIGRILLSLLPSDTQAVAGLTLGADPIVTAVSVVSAYENRPIPALIIRKEAKGHGTKAYIEGPNLPEGAKVVVLEDVVTTGQSAMKAVDRLRAAGYVVDEVISLVDRQQGGAEFYQSVGLKFEAVFTIMDLQQRYQELGN
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: HIS1_NITOC
Sequence: MVEPLKLALSKGRIFQEILPLLAIAGIYPRDDPKTSRKLVLDTNQADLKLVIIRAADVPTYVEYGAADFGVAGKDVLLEHPGNGLYEPLDLRIACCRMMVAGEPEVTPRSGRLRIATKYVHSTRRFYAERGEQVEVIKLYGSMELAPLVGLADRIVDLVDTGNTLRANGLAPLEHITDISSRLVVNKASMKMRHQRIKKFICLMAEAVEKQHG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_NOCFA
Sequence: MATDRQYEDLLRLVLDTGTAKGDRTGTGTRSIFGHQLRYDLSAGFPLITTKKVHLKSIVYELLWFLRGDSNVGWLREHGVTIWDEWADPQGELGPVYGVQWRSWPTPDGTHIDQISQVLQTLRTDPDSRRMIVSAWNVAELDRMALAPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASYALLTHMVAQQTELEPGEFIWTGGDCHIYDNHVEQVTEQLGREPYPFPRLELRPAPSLFDYRFEDVTVTDYRHHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDR_ORYSJ
Sequence: MGGGDGGAGKAKARPVFSSFMTVFMHADAADVALMVLGLLGAMGDGISTPVMLLITSRIFNDLGSGADIVKEFSSKVNVNARNLVFLAAASWVMAFLEGYCWARTAERQASRMRARYLRAVLRQDVEYFDLKKGSTAEVITSVSNDSLVVQDVLSEKVPNFVMNAAMFAGSYAVGFALLWRLTLVALPSVVLLIIPGFMYGRILVGLARRIREQYTRPGAIAEQAVSSARTVYSFVAERTTMAQFSAALEESARLGLKQGLAKGIAVGSNGITFAIWAFNVWYGSRLVMYHGYQGGTVFAVSAAIVVGGLALGSGLSNVKYFSEASSAAERILEVIRRVPKIDSESDTGEELANVTGEVEFRNVEFCYPSRPESPIFVSFNLRVPAGRTVALVGGSGSGKSTVIALLERFYDPSAGEVMVDGVDIRRLRLKWLRAQMGLVSQEPALFATSIRENILFGKEEATAEEVVAAAKAANAHNFISQLPQGYDTQVGERGVQMSGGQKQRIAIARAILKSPKILLLDEATSALDTESERVVQEALDLASMGRTTIVIAHRLSTIRNADIIAVMQSGEVKELGPHDELIANDNGLYSSLVRLQQTRDSNEIDEIGVTGSTSAVGQSSSHSMSRRFSAASRSSSARSLGDARDDDNTEKPKLPVPSFRRLLMLNAPEWKQALMGSFSAVVFGGIQPAYAYAMGSMISVYFLTDHAEIKDKTRTYALIFVGLAVLSFLINIGQHYNFGAMGEYLTKRIREQMLAKILTFEIGWFDRDENSSGAICSQLAKDANVVRSLVGDRMALVIQTISAVLIACTMGLVIAWRLALVMIAVQPLIIVCFYARRVLLKSMSKKSIHAQAESSKLAAEAVSNLRTITAFSSQERILRLFEQSQDGPRKESIRQSWFAGLGLGTSMSLMTCTWALDFWYGGRLMAEHHISAKELFQTFMILVSTGRVIADAGSMTTDLAKGADAVASVFAVLDRETEIDPDNPQGYKPEKLKGEVDIRGVDFAYPSRPDVIIFKGFTLSIQPGKSTALVGQSGSGKSTIIGLIERFYDPIRGSVKIDGRDIKAYNLRALRRHIGLVSQEPTLFAGTIRENIVYGTETASEAEIEDAARSANAHDFISNLKDGYDTWCGERGVQLSGGQKQRIAIARAILKNPAILLLDEATSALDSQSEKVVQEALDRVMIGRTSVVVAHRLSTIQNCDLITVLEKGTVVEKGTHASLMAKGLSGTYFSLVNLQQGGNQQVQH
What are the official names of this protein?
Putative multidrug resistance protein, P-glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: OADC_RHOP5
Sequence: MAWRNRRGALRAILSGSHCTRPASVYDPISMRIADDLGFEVGMFGGSVASLAILGDPDIALITLTELAEQVRRMSRAAALPVLVDADHGYGNALNVRRTVQELEAAGAAGLTIEDTLLPQAFGETQPQLISLAEGQGKINAALDARGDPSLVIIGRTGALAITSLDDAIERAQAYQAAGVDALFFTGVKTRPQLDAIAAATTLPIVLGGPSEAITDWDYLAERRVRIAVQGHAPIAAATRAVFETLQAVRNGAAPKQLSGLAAAELMQRVTRGDVVDERCDHFLGLKRS
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate into pyruvate.  Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
What are the official names of this protein?
Oxaloacetate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
Protein: HOA_THET8
Sequence: MSWDLSTAKPPVVVDTTLRDGSHAHRHQYTVEEARAIAQALDEAGVYAIEVSHGDGLGGSSLQYGFSRTDEMELIRAVRETVRRAKVAALLLPGIGTRKELKEAVEAGIQMVRIATQCTEADISEQHFGMAKEMGLEAVGFLMMSHMRPPEFLAEQARLMEGYGADVVYIVDSAGAMLPEDAYARVKALKEALSRAKVGFHAHNNLGLAIGNTLAALAAGADWVDATLRGYGAGAGNAPLEVLAAVLDKAGLNPGLDVFKLLDAAEYVMGPILHFQPYPDRDSVAIGYAGVYSTFLLHAKRIGKELGVDPLAILLELGRRQAVAGQEDWILRVALELKEKEAGALAD
What is the function of this protein?
Catalyzes the retro-aldol cleavage of both 4-hydroxy-2-oxopentanoate (HOPA) and 4-hydroxy-2-oxohexanoate (HOHA) to pyruvate and acetaldehyde or propanaldehyde, respectively.  The aldehydes produced by this reaction are directly channeled to the dehydrogenase TTHB247, ensuring that these toxic aldehydes are sequestered from cellular components.  Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.  Appears to be stereospecific since it can cleave (4S)-4-hydroxy-2-oxopentanoate but not the (4R) isomer.  Is not able to catalyze the aldol addition of 2-oxobutyrate with acetaldehyde; this indicates that the enzyme is specific for pyruvate as the carbonyl donor.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxohexanoate aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: ACP_JANMA
Sequence: MSDIEQRVKKIVAEQLGVAEADIKIESSFVDDLGADSLDTVELVMALEDEFEMEIPDEQAEKITTVQQAIDYAKAHVKA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR8_BACSU
Sequence: MIERYSRPEMSAIWTDENRFQAWLEVEILACEAWAELGVIPKEDVKVMRENASFDINRILEIEKDTRHDVVAFTRAVSESLGEERKWVHYGLTSTDVVDTALSYLLKQANDILLKDLERFVDIIKEKAKEHKYTVMMGRTHGVHAEPTTFGLKLALWHEEMKRNLERFKQAKAGIEVGKISGAVGTYANIDPFVEQYVCEKLGLKAAPISTQTLQRDRHADYMATLALIATSIEKFAVEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSENMTGMARVIRGYMMTAYENVPLWHERDISHSSAERIILPDATIALNYMLNRFSNIVKNLTVFPENMKRNMDRTLGLIYSQRVLLALIDTGLTREEAYDTVQPKAMEAWEKQVPFRELVEAEEKITSRLSPEKIADCFDYNYHLKNVDLIFERLGLA
What is the function of this protein?
Catalyzes two reactions in de novo purine nucleotide biosynthesis.  Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate (PubMed:15182182).  Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability.
What are the official names of this protein?
Adenylosuccinate lyase, ASL, Adenylosuccinase, ASase, Glutamyl--tRNA ligase regulatory factor.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
Protein: RL9_TREPA
Sequence: MKIILNQDVKILGEEGDVKEVAAGYFRNYLYPRNLAVPHNRFTVARFKQRQQDIEMRKSLKRQDAANLKARLEAQPVVIAMPAGTNGKLYGAVTSHTVAEQLACMGFEVERKRVEVPGLTLKCVGNYHVTIRLYEEICAVVPVTIKNQSEADSVSE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: VPP1_MOUSE
Sequence: MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPNEMGRGAPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTHGFQNIVDAYGIGTYREINPAPYTVITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKHENEMFSMVFSGRYIILLMGLFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFTQGNWTEETLLGSSVLQLNPAIPGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMSSLFGYLVILIFYKWTAYDAHSSRNAPSLLIHFINMFLFSYPESGNAMLYSGQKGIQCFLIVVAMLCVPWMLLFKPLILRHQYLRKKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLHVRSLAGGLGLFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIREGKFDE
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for the acidification of various organelles, such as lysosomes, endosomes, the trans-Golgi network, and secretory granules, including synaptic vesicles.  In certain cell types, can be exported to the plasma membrane, where it is involved in the acidification of the extracellular environment (By similarity).  Required for assembly and activity of the vacuolar ATPase (By similarity).  Through its action on compartment acidification, plays an essential role in neuronal development in terms of integrity and connectivity of neurons (PubMed:33833240).
What are the official names of this protein?
V-type proton ATPase 116 kDa subunit a 1, V-ATPase 116 kDa subunit a 1, Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit, Vacuolar adenosine triphosphatase subunit Ac116, Vacuolar proton pump subunit 1, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Melanosome.
Protein: NHAA_LEGPC
Sequence: MNKSDSFYNLETIGGILLFIAAVLAIITANSPYRVGYEYFLSINGSVSVGNMSITKPLLLWINDGLMAIYFLLIGLEIKREVNRGILSDKTNLLVPALTALAGLLFPALIFIFFNAHHPVYLKGWAIPTATDIAFTLGIVSLLGSRVPFSLKILLTAIAIFDDIAAIVIIALFYTEQLSLLSLSLALVFTLILIGLNYFKCRRISVFMLFGVALWIAVLKSGVHATLAGIVIAMTIPDEGKESMLTRLEDGLHHWVVFLILPLFAFANAGVSFVGLDASMLTHPVVLGIGLGLFLGKQLGIFLSLGYFVQFKKFLKADKVNLAQVYGIALICGVGFTMSLFIGSLAYQNYDLSLMPMVKIGVVFGSFIAGLTGFLVLKMTSLKR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMM_PSEU2
Sequence: MNATPASADDLIVIGKIYSVHGVRGEVKVYSFTDPIGNLLDYKTWTLRREGSVDKQVELVSGRLQSKFLVTKLKGLDDREEARLLSGYEICVPRNLFPDLDDGEYYWYQLEGLKVIDQLGQLLGKIDHLLETGSNDVMVVKPCAGSLDDRERLLPYTEQCVLAIDMAAGEMKVDWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODO2_STAAR
Sequence: MPEVKVPELAESITEGTIAEWLKNLGDSVEKGEAILELETDKVNVEVVSEEAGVLSEQLASEGDTVEVGQAIAVIGEGSGNASKENSNDNTPQQNDETTNNKKEETTNKSADKAEVNQTNDDNQQRVNATPSARRYARENGVNLAEVSPKTNDVVRKEDIDKKQQAPASTQTTQQAPAKEEKKYNQYPTKPVIREKMSRRKKTAAKKLLEVSNNTAMLTTFNEVDMTNVMELRKRKKEQFMKDHDGTKLGFMSFFTKASVAALKKYPEVNAEIDGDDMITKQYYDIGVAVSTDDGLLVPFVRDCDKKNFAEIEAEIANLAVKAREKKLGLDDMVNGSFTITNGGIFGSMMSTPIINGNQAAILGMHSIITRPIAIDQDTIENRPMMYIALSYDHRIIDGKEAVGFLKTIKELIENPEDLLLES
What is the function of this protein?
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, 2-oxoglutarate dehydrogenase complex component E2, OGDC-E2, Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: HSPQ_SALPA
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPEYSLDEPSPDELAVNDELRAAPWYHVVMEDDNGQPVHTYLAEAQLRSEMRDEHPEQPSMDELARTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.