PharMolix/UniProtQA huggingface dataset:
Protein: H2BL2_PSAMI
Sequence: MPAKQTSGKGAKKAGKAKGRPSGASKTRRRKRKESYGIYIYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLSQYNKKSTISSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTTSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Late histone H2B.2.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YFIL_ECOLI
Sequence: MMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISGSAIKDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQLHEVWQKGADENASTIRLN
What are the official names of this protein?
Uncharacterized protein YfiL, URF2.
Protein: RAGP1_ARATH
Sequence: MDHSAKTTQNRVLSVKMWPPSKSTRLMLVERMTKNITTPSIFSRKYGLLSVEEAEQDAKRIEDLAFATANKHFQNEPDGDGTSAVHVYAKESSKLMLDVIKRGPQEESEVEVSKDGDVFFDISGGSRAFIEEEEARDLLRPLADPRNSYTKIRFSNRSFGSEAAKFAASVLSSIKDQLTEVDLSDFVAGRPEAEALEVMNMFSSALEGSKLRYLNLSDNALGEKGIRAFASLINSQHDLEELYLMNDGISEDAARAVRELLPSTDKIRVLQFHNNMTGDEGATAIAEIVRECPSLEDFRCSSTRIGSEGGVALAEALEHCSHLKKLDLRDNMFGVEGGIALAKTLSVLTHLTEIYMSYLNLEDEGTEALSEALLKSAPSLEVLELAGNDITVKSTGNLAACIASKQSLAKLNLSENELKDEGTILIAKAVEGHDQLVEVDLSTNMIRRAGARALAQTVVKKNTFKLLNINGNFISEEGIDEVNDMFKDCLDKLVPLDDNDPEGEDFEDEDEEEEGEDGNELESKLGSLKIKQGEE
What is the function of this protein?
GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state.  Plays a role in spatial signaling during cell division.
What are the official names of this protein?
RAN GTPase-activating protein 1, AtRanGAP1, RanGAP1.
What is the protein family that this protein belongs to?
Belongs to the RNA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus envelope. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Note=Localized in patchy areas at the nuclear envelope (NE) of interphase cells. Concentrates at the preprophase band (PPB) and remains associated with the cortical division site (CDS) during mitosis and cytokinesis. During mitosis, associates with mitotic spindles at the anaphase. Associated to the microtubular phragmoplast and the surface of the daughter nuclei at the telophase.
Protein: ATPB_PROMM
Sequence: MAAAATATAGTKGVIRQVIGPVLDVEFPAGKLPKILNALRIEGKNPSGQDVAITAEVQQLLGDHRVRAVSMSSTDGLVRGMEALDTGAAISVPVGEATLGRIFNVLGEPVDEQGPVTTDATAPIHRPSPKLTELETKPTVFETGIKVIDLLAPYRQGGKVGLFGGAGVGKTVLIQELINNIAKEHGGVSVFGGVGERTREGNDLYEEFKESGVINSDDLSKSKVALCFGQMNEPPGARMRVGLSALTMAEHFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGALQERITSTLEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLARALAAKGIYPAVDPLDSTSTMLQPSVVGDEHYRTARSVQATLQRYKELQDIIAILGLDELSEDDRRTVDRARKIEKFLSQPFFVAEIFTGMSGKYVKLEETIAGFNMIMSGELDHLPEQAFYLVGNIDEVKAKAEKMASEAKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RMF_VIBCJ
Sequence: MKRQKRDRLERAQSQGYKAGLNGRSHDECPYQQTEVRSYWLGGWRDARNDKLSGLCK
What is the function of this protein?
During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).
What are the official names of this protein?
Ribosome modulation factor, RMF.
What is the protein family that this protein belongs to?
Belongs to the ribosome modulation factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_STAA2
Sequence: MTKITVFGMGSFGTALANVLAENGHDVLMWGKNQDAVDELNTCHTNKKYLKYAKLDVNIIATSDMTKAIQFADIYLMALPTKAMREVATQINDKLTSKKTFIHVAKGIENGTFKRVSEMIEDSISPEYNAGIGVLSGPSHAEEVVVKQPTTVAASSKDKSVSKLTQDLFMNDYLRVYTNDDLIGVELGGALKNIIAVASGIVAGIGYGDNAKAALMTRGLAEISRLGEKLGADPMTFLGLGGIGDLIVTCISTHSRNFTLGYKLGQGESMDQALSEMNMVVEGIYTTKSVYHLAKEKNVDMPITNALYRVLFENISVKECVKDLMERDKKSE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRYAA_BOVIN
Sequence: MDIAIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKIPSGVDAGHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens (By similarity).  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions (PubMed:20440841).  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA (By similarity).
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: ORDA_ASPFL
Sequence: MIYSIIICAGALLGLWILEKLLAPKDTRPPLPPGPWRKPIIGNLTDFPPKGTPEWLFWAKHQERYGPMSSLEVMGQTIIMINDAQLGIEIMHKKSALSQMIPDAPFAHMAGWGMSLATERNRQAWKTIRANMKQEIGTRRAISTFHPKMEIGIRRFLLRTLDNPDDLRFHIRKEANAFMMDVAYGYTIAPHGKDELYDLTQQSVRQFSHIFSPGEWSVNFFPILRYVPSWFPGASFQIKAAEYKRTIERMTMVPYLWIKDQVARGCSRPSILLRLLQKGHYESGSHQEQVLVWTNAEFVMGGSDTTVSAVSSFFVAMALYPEVQRKAREELDRVVGPTTLATFEHRSQLPFIDALVKEVFRWHPASPLGAPHITQEDQIWDGYLLPKGALLLPNIWTFTHDPSVYHDPMVFKPERFLEGKDSPPETDPMKFVFGFGRRICPGRFVTDEKLFLIACHAVSCFFISPKDPGAPEPDWLPGVISQPGAFDLNVVPRSPAHEELIRSIETDHPWKNADATDISRFMARNQMI
What is the function of this protein?
Converts O-methylsterigmatocystin (OMST) to aflatoxin B1 and converts dihydro-O-methylsterigmatocystin (DHOMST) to aflatoxin B2 in the aflatoxin biosynthesis pathway.
What are the official names of this protein?
O-methylsterigmatocystin oxidoreductase, OMST oxidoreductase, Aflatoxin B synthase, Aflatoxin biosynthesis protein Q, Cytochrome P450 64.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: UVRA_SYNY3
Sequence: MPEQNSIRIRGARQHNLKNVNLDLPRDRLIVFTGVSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQLDKPDVDSIEGLSPAISIDQKSTSHNPRSTVGTVTEIYDYLRLLFGRAGSPHCPHCQRNIAPQTIDQMCDRVMELPDRTKFQILAPVVKGKKGTHVQLLSSLVSQGFVRVRINGEVRELSDNIELKKNQAHTIEIVIDRLIKKEGLQERLVDSLSTCLKQAEGTAIIDILDKPTLAVLDGGKKDDKEALKAAENGQAYHAELPKEIIFSENFACPEHGAVMDELSPRLFSFNSPYGACPDCHGIGFVRSFCPDLVIPDPEKPVYVAIAPWSEKDNSYYLSLLYSLGQHFDFQLQTPWKKLTKEQKEIILYGTEEEIWFEGESRYRNKQGYYRRFAGALNILQKNYDETNSDAIKQKLEKYIINQPCHTCGGKRLKPEALAVKLGQYNINNLTSVPIRQTLERIENLELTSRQAMIGELALKEIKARLQFLLDVGLDYLTLDRAAMTLSGGEAQRIRLATQIGSGLTGVLYVLDEPSIGLHQRDNNRLLATLTKLRDLGNTLIVVEHDEDTIRHADYIVDIGPKAGIHGGEIVCQGDFQTLLKNQRSLTGAYLSGREAIATPEERRNGNGAKLTLQGCCHNNLRNIDVTIPLGKLVCVTGVSGSGKSTLVNELLHPALQHYLSRQVAFPKNLGEITGLQAIDKVIVIDQSPIGRTPRSNPATYTGIFDSIREIFTQTIEAKARGYKPGQFSFNVKGGRCEACAGQGVNVIEMNFLPDVYVQCDVCKGARYNRETLQVKYKGHSIADVLAMTTEEALTVFENIPRAVNRLQTLVDVGLGYIKLGQPAPTLSGGEAQRVKLASELSRRATGKTLYLIDEPTTGLSFYDVHHLLNVLQRLVDKGNSVLVIEHNLDVIRCSDWIIDLGPEGGDRGGKIMVAGTPETVAQHPSSYTGKYLAKVLQS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU70_DROME
Sequence: MSTWNPENDVDLLSGSEDEEDVSMKRDYHGREAILFVVDANLQTAGVERLLEALNIIRTAFISGLLVNDKDLIGLIFANTKHSPPPLEASALDNIVMPDNCAVFLPLRQLTKPIVEHYLEFMGGVETQFADVYGLAEPDGRGRFDLMIRLCIEMLEKCGKKLNNAKIAYVTDVREPHPSNSNHFQAALQKASDLEGKEFEFHVIPMVDDFDYEPFYKEFITLSRAIELDAFQVPDAQMLREILSDRKLKQDFLRRCLGHFSFYLGPNLSMSVQYYNYFQRRAYPRKVQILRRDNSVVRTKRVITVQKQKDDGSQDIEHEYQIKVTGGWYTCNVGERDLRISMDQLNRVRNLHKPQMMLLGFKHRSSLPEVSYIKPANFMYPDDQSIIGSKRLFRALWERCLVRDKIAICLFMCKRKSIPRYVALVPVEAPDNGEDKNYRSLLCGDGFKIVYLPEAKHIRHLDLQDWNNTENTADEQKVEFFQKIIKKLRVDYQPNLINDPSLDALQANLLALSLDFSTDTKGLDNLLDTSQQDKRIEKLLPDYEMFAPEAEPHKKRAAKSTTAGASGPKMAKIDDDQLKEFEFVKSLNKDEALTSCTAAQLHFILQHHFDVTMPKSSKKAKLVAKIEELHK
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair (By similarity).  Sequence-specific DNA-binding protein that has a high affinity for a 31 bp sequence in the Yp1 gene.  Site-specific DNA binding to 31 bp P element inverted repeats.
What are the official names of this protein?
ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II subunit dp70, ATP-dependent helicase Irbp, Inverted repeat-binding protein, Yolk protein factor 1 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ku70 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YBK8_YEAST
Sequence: MEMLLFLNESYIFHRFRMWSIVLWHSCVFVCAECGNAYYRGAGGCLEKPFCAPVKFPFSVKKNIRILDLDPRSEAYCLSHHLVCPKRFPCKATSLLLIPEG
What are the official names of this protein?
Putative UPF0377 protein YBL108W.
What is the protein family that this protein belongs to?
Belongs to the UPF0377 family.
Protein: LLDD_ECOSE
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPTALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: WFDC9_HUMAN
Sequence: MKPWILLLVMFISGVVMLLPVLGSFWNKDPFLDMIRETEQCWVQPPYKYCEKRCTKIMTCVRPNHTCCWTYCGNICLDNEEPLKSMLNP
What are the official names of this protein?
Protein WFDC9.
What are the subcellular locations of this protein?
Secreted.
Protein: PNP_ACIB5
Sequence: MSMFNIVRKEFQFGQHQVVLETGRVARQANTVLITMGGVTVLVAVVAAPTAKAGQDFFPLTVNYQEKQYAAGRIPGGYGKREGRASEAETLISRLIDRPIRPLFPEGYYNEIQVTATVVSSDKTMEADIAAMLGTSAALAIAGTPFRGPIGAARVGLINGEYVLNPNFEQMAQSDLDLVVAGTESAVLMVESEAKELSEDQMLGAVLFGHDEMQIAIQAINEFAAAAGAKPSDWVAPAHNEELRAKLKEAFEAKISEAYTIAVKQDRYAALDALHAEAVAQFVPEEDVDGIADEVDYLFEDLKYRTVRDNILSGKPRIDGRDTKTVRALDVQVGVLERAHGSALFTRGETQALVTTTLGNTRDALMVDTLAGTKTDNFMLHYNFPAYSVGETGRESGPKRREIGHGRLARRGVQAVLPAADRFPYVIRIVSDITESNGSSSMASVCGASLSLMDAGVPLKAPVAGIAMGLVKEGERFAVLSDILGDEDHLGDMDFKVAGSANGITALQMDIKIEGITEEIMEVALNQAFAGRMHILNEMNKVISRARPEISMHAPTFEVITINPDKIRDVIGKGGATIRQITEETKAAIDIEDNGTVRVFGETKAAAKAAIAKIQAITAEVEPGKIYDGKVIRIVEFGAFVNIMPGTDGLLHISQISNERIANVTDVLKEGQEVKVQVQDVDNRGRIKLTMKDIEQA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_STRPM
Sequence: MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIVRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVERLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVIQKEKDKQADYQAKYDATQERIAEMKKIKS
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_POLSJ
Sequence: MSLFELILLAPVDEIETLSEALDALDALSVSVEDADAQTPAEQALFGEPGMPPPKAGWERSRVVSLFASEALARDAASVLTAQDFFAGCQLVAIQAVPEQDWVRLTQSQFTPVEITPEFWIVPTWHEPPEQAKQLIRLDPGLAFGTGTHPTTRMCLRWIAGQGAANKPLARVLDYGCGSGILAIGAAKFGAVDIDAVDIDEAAVESTRANAEANHVTLNAGLPDKAVGAYQTVLANILATPLKVLAPLLCSHVQKGGSLVLAGILERQADELKAAYQPYCQLQVLDQEEGWILMGARF
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_BURL3
Sequence: MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQNGERVVLLTQQIVREDANLLYGFLTPQERTTFRELLKITGIGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKTAERLLLELKGKLGADLGELAGAASPSDHATDILNALLALGYSEKEGLAAIKNVPAGTGVSEGIKLALKALSKV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SYI_CALS8
Sequence: MDWSQTLNLPKTDFPMRANLAQREPQFLRFWEENDIFKKMLKKNRNNKKFILHDGPPYANGDIHLGHALNKVLKDIVNKYKSLQGYYTPYIPGWDTHGLPIEQQVIKKLGVNRHEVDPVEFRKKCKEFALSYIDIQRQQFKRLGVFGEWEDPYMTLDPKFEARQIRVFGEMAKKGYIYKGLKPVYWCPSCETALAEAEIEYQEDKTYSIYVKFEVIDDKGLFANLNLSGKKVYIVIWTTTTWTLPGNLAIALNTDFDYSLVDVGNEILIVASELVERVMKTNKIDQYHEIARFKGKDLEYVKCKHPFLDRTSLVILGEHVTLEAGTGCVHTAPGHGEEDFEVCERYNIPVIVPVDNKGYLTQEAGKFAGLFYEDSNKEIAKELEASDHLLGVEKITHQYPHCWRCKNPVIFRATEQWFASVKGFREEALKAVDDVKWVPEWGRDRIYNMIADRQDWCISRQRIWGVPIPIFYCKNCRKELITDETIDHIAKIFEKEGSDAWFSKDVKELLPEGTKCPVCGCMEFEKETDIMDVWFDSGSSHAYVLESREDLEWPCDMYLEGNDQYRGWFQSSLLTAVATKGRAPYRIVLTHGFVVDGEGKKMSKSEGNVISPFDIINEFGADILRLWCVSADYTTDMRISKDIIKQLTEIYRKIRNTARFLLGNLYDFNPKTDKVGCENLKEIDKWALQRLYKLIEKVTKAYEEYDYNQVYHLVHNFCVIDMSNLYLDINKDRLYASKSESLDRRSAQTVMYEILVALTKLIAPILSFTAEEIWQNIIFKEEDAESVFLTSWPKVNENILKDETLEEKWNKIIEIKDIVAKQLEIARNEKLIGSSLDSKVKIFAKGNIKRFIEENKDIIQEVLIVSQLEVEEGDSDQIKVEVYKADGLKCERCWKFDTMVGKNEENLNVCPRCYEVVKVK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_STUS1
Sequence: MAKPAARPRKKVKKTVVDGIAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQIAAERAGQAALEYGLKNLDVNVKGPGPGRESAVRALNACGYKIASITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RPOC_CAMJR
Sequence: MSKFKVIEIKEDARPRDFEAFQLRLASPEKIKSWSYGEVKKPETINYRTLKPERDGLFCAKIFGPIRDYECLCGKYKKMRFKGVKCEKCGVEVANSKVRRSRMGHIELVTPVAHIWYVNSLPSRIGTLLGVKMKDLERVLYYEAYIVENPGDAFYDNESTKKVEYCDVLNEEQYQNLMQRYENSGFKARMGGEVVRDLLANLDLVALLNQLKEEMGATNSEAKKKTIIKRLKVVENFLNSNLNANTDSDEAVPNRPEWMMITNLPVLPPDLRPLVALDGGKFAVSDVNDLYRRVINRNTRLKKLMELDAPEIIIRNEKRMLQEAVDALFDNGRRANAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPKLRMDQCGLPKKMALELFKPHLLAKLEEKGYATTVKQAKKMIENKTNEVWECLEEVVKGHPVMLNRAPTLHKLSIQAFHPVLVEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKSVTVPSQDMVLGIYYLSLEKAGAKGSHKICTGIDEVMMALESKCLDIHASIQTMVDGRKITTTAGRLIIKSILPDFVPENSWNKVLKKKDIAALVDYVYKQGGLEITASFLDRLKNLGFEYATKAGISISIADIIVPNDKQKAIDEAKKQVREIQNSYNLGLITSGERYNKIIDIWKSTNNVLSKEMMKLVEKDKEGFNSIYMMADSGARGSAAQISQLAAMRGLMTKPDGSIIETPIISNFREGLNVLEYFISTHGARKGLADTALKTANAGYLTRKLIDVAQNVKITIEDCGTHEGVEINEITADSSIIETLEERILGRVLAEDVIDPITNSVLFAEGTLMDEEKAKILGESGIKSVNIRTPITCKAKKGICAKCYGINLGEGKLVKPGEAVGIISAQSIGEPGTQLTLRTFHSGGTASTDLQDRQVSAQKEGFIRFYNLKTYKNKEGKNIVANRRNAAVLLVEPKIKTPFKGVINIENIHEDVIVSIKDKKQEVKYILRKYDLAKPNELAGVSGSIDGKLYLPYQSGMQVEENESIVEVIKEGWNVPNRIPFASEILVEDGEPVVQNIKAGEKGTLKFYILKGDGLDRVKNVKKGDIVKEKGFFVVIADENDREAKRHYIPRESKIEFNDSEKIDDANTIIASAPKKERKVIAEWDAYNNTIIAEIDGVVSFEDIEAGYSADEQIDEATGKRSLVINEYLPSGVRPTLVIAGKGDKAVRYHLEPKTVIFVHDGDKIAQADILAKTPKAAAKSKDITGGLPRVSELFEARKPKNAAVIAEIDGVVRFDKPLRSKERIIIQAEDGTSAEYLIDKSKHIQVRDGEFIHAGEKLTDGVVSSHDVLKILGEKALHYYLISEIQQVYRGQGVVISDKHIEVIVSQMLRQVKVVDSGHTKFIEGDLVSRRKFREENERIIRMGGEPAIAEPVLLGVTRAAIGSDSVISAASFQETTKVLTEASIAGKFDYLEDLKENVILGRMIPVGTGLYGEQNLKLKEQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: YHAI_BACSU
Sequence: MDSMDHRIERLEYYIQLLVKTVDMDRYPFYALLIDKGLSKEEGEAVMRICDELSEELATQKAQGFVTFDKLLALFAGQLNEKLDVHETIFALYEQGLYQELMEVFIDIMKHFD
What are the official names of this protein?
Uncharacterized protein YhaI.
Protein: TRP2_NEZVI
Sequence: APAAGFFGMR
What are the official names of this protein?
Tachykinin-related peptide 2, TKRP-2.
What are the subcellular locations of this protein?
Secreted.
Protein: BGLS_BUTFI
Sequence: MEKWARIKYTPNLPLGENGERVTASQKHIELSCEAACEGMVLLKNDRNVLPIRKGTRVALFGKGVFDYVKGGGGSGDVTVPYIRNLYEGLSQYTSDISIYDKSVRFYQEYVADQYRLGIAPGMIKEPALPEDILADAAAYADTAIIAISRFSGEGWDRKVAGVDREIKCEAKDLVEQGNKIFDHGDFYLTNAEKKMVKMVKENFSSVIVVMNVGGVVDTTWFKKDDQISSVLMAWQGGIEGGLAAARILLGKVNPSGKLSDTFAARLEDYPSTEGFHEDDDYVDYTEDIYVGYRYFETIPGAKEKVNYPFGYGLSYTTFLLEDYKAEPFVASAADEVGKSDSDLADAIVASVTVTNIGKIPGKEVVQLYYSAPQGKLGKPAKVLGGYAKTRLLQPGESQRVTIALYMEDMASYDDLGKVKKAAWLLEKGEYHFFLGTSVRDTRLLDYTYELSKNIIVEQVSNKLVPTSLPKRMLADGTYEELPQTEPVDTYATIFPRPKNWKETIEHDVLKTPVVRPQDRFQLFLPPKEGDPKKFIEVAECKVTLEDFIAQLSNEQLASLLGGQPNVGMANTFGYGNLPEVGVPNAQTCDGPAGVRIAPEVGVVTTAFPCSTLLACTWNEDICYEVGVAGGEEAKECNFGAWLTPAVNIHRSPLCGRNFEYYSEDPFLAGKQAAAMVRGIQSNNIIATPKHFALNNKESNRKGSDSRASERAIREIYLKAFEIIVKEQSPGASCLQYNIVNGQRSSESHDLLTGILRDEWGFEGVVVSDWWGFGEHYKEVLAGNDIKMGCGYTEQLLEAIDKKALKRKDLEKRQSESSRCFSNSTKLKAA
What is the function of this protein?
B. fibrisolvens beta-glucosidase hydrolyzes cellobiose to a limited extent, cellotriose to cellobiose and glucose, and cellotetraose and cellopentaose to predominantly glucose.
What are the official names of this protein?
Beta-glucosidase A, Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
Protein: MTUS1_HUMAN
Sequence: MTDDNSDDKIEDELQTFFTSDKDGNTHAYNPKSPPTQNSSASSVNWNSANPDDMVVDYETDPAVVTGENISLSLQGVEVFGHEKSSSDFISKQVLDMHKDSICQCPALVGTEKPKYLQHSCHSLEAVEGQSVEPSLPFVWKPNDNLNCAGYCDALELNQTFDMTVDKVNCTFISHHAIGKSQSFHTAGSLPPTGRRSGSTSSLSYSTWTSSHSDKTHARETTYDRESFENPQVTPSEAQDMTYTAFSDVVMQSEVFVSDIGNQCACSSGKVTSEYTDGSQQRLVGEKETQALTPVSDGMEVPNDSALQEFFCLSHDESNSEPHSQSSYRHKEMGQNLRETVSYCLIDDECPLMVPAFDKSEAQVLNPEHKVTETEDTQMVSKGKDLGTQNHTSELILSSPPGQKVGSSFGLTWDANDMVISTDKTMCMSTPVLEPTKVTFSVSPIEATEKCKKVEKGNRGLKNIPDSKEAPVNLCKPSLGKSTIKTNTPIGCKVRKTEIISYPRPNFKNVKAKVMSRAVLQPKDAALSKVTPRPQQTSASSPSSVNSRQQTVLSRTPRSDLNADKKAEILINKTHKQQFNKLITSQAVHVTTHSKNASHRVPRTTSAVKSNQEDVDKASSSNSACETGSVSALFQKIKGILPVKMESAECLEMTYVPNIDRISPEKKGEKENGTSMEKQELKQEIMNETFEYGSLFLGSASKTTTTSGRNISKPDSCGLRQIAAPKAKVGPPVSCLRRNSDNRNPSADRAVSPQRIRRVSSSGKPTSLKTAQSSWVNLPRPLPKSKASLKSPALRRTGSTPSIASTHSELSTYSNNSGNAAVIKYEEKPPKPAFQNGSSGSFYLKPLVSRAHVHLMKTPPKGPSRKNLFTALNAVEKSRQKNPRSLCIQPQTAPDALPPEKTLELTQYKTKCENQSGFILQLKQLLACGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTEQAVLQESLEKESKVNKRLSMENEELLWKLHNGDLCSPKRSPTSSAIPLQSPRNSGSFPSPSISPR
What is the function of this protein?
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation.  May be required for AGTR2 cell surface expression.  Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation.  Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
What are the official names of this protein?
Microtubule-associated tumor suppressor 1, AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, Mitochondrial tumor suppressor 1.
What is the protein family that this protein belongs to?
Belongs to the MTUS1 family.
What are the subcellular locations of this protein?
Mitochondrion. Golgi apparatus. Cell membrane. Nucleus. Note=In neurons, translocates into the nucleus after treatment with angiotensin-II. SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes with the mitotic spindle during mitosis and with the intercellular bridge during cytokinesis.