PharMolix/UniProtQA huggingface dataset:
Protein: SYT_PSEP1
Sequence: MPVITLPDGSQRSFDHAVSIAEVAASIGAGLAKATVAGKVDGKLVDACDLISNDATLQIITPKDEEGLEIIRHSCAHLVGHAVKQLYPTAKMVIGPVIDEGFYYDIAYERPFTPEDMAAIEKRMMELIEKDYDVVKKMTPRAEVIDVFTARGEDYKLRLVEDMPDEQAMGLYYHEEYVDMCRGPHVPNTRFLKAFKLTKLSGAYWRGDAKNEQLQRVYGTAWADKKQLAAYIQRIEEAEKRDHRKIGKQLDLFHLQEEAPGMVFWHANGWTVYQVLEQYMRGVQRENGYQEIKTPQVVDRILWERSGHWSNYAENMFTTSSESRDYAVKPMNCPCHVQVFNQGLKSYRDLPLRLAEFGACHRNEPSGALHGIMRVRGFVQDDAHIFCTEEQVKKEAADFIKLTLDVYKDFGFSDIAMKLSTRPAKRVGSEELWDRAETALADALNESGLEWEYQPGEGAFYGPKIEFTLRDCLGRNWQCGTLQYDPNLPERLDASYIAEDNSRVRPVMLHRAILGSFERFIGMLIEHYAGVFPAWLAPTQAVIMNITDKQTDFALEVEKSLNGSGFRAKSDLRNEKIGFKIREHTLLKVPYLLVIGDREVETQTVAVRTREGADLGSMPVAQFVELLTQAVSRRGRQESE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM_HAEDU
Sequence: MTYQLPELGYAYDALEPYFDKETMEIHHSKHHQAYVNNSNALLEKHPELLEKCPGALLKDLTQVPAEKRTAVRNNLGGHVNHTLFWKGLKTGTTLQGALKDAIIRDFGSVEAFQAEFEQAAATRFGSGWAWLVLEEGKLAVVSTANQDSPIMGKDVAGVSGYPIFTLDVWEHAYYLHYQNRRPDYIKAFWNVVNWDEASRRFEEKQAGCGCTK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: ENGB_CHLPB
Sequence: MKIRNATFYKSVSAIDHLPKEQLPEIVFVGRSNVGKSTLLNSLTARKGLAKTSSTPGKTQLINYFVINESCYFVDLPGYGYAKVDKGKKYEWGKLLSHYVSTRDSITLVVLLIDSRHPDMESDHLMAEFLEHCGRPYGVVLTKYDKLKQQAKAAARLAVKSYSLKSKFIVNYSAISGQGKEELLEQLAIYTG
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PSBF_SARHE
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ALF2_STAAM
Sequence: MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTIVKMVEGLMHDLNITIPVAIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRAK
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: URE1_ALCBS
Sequence: MATMSRQAYADMFGPTTGDRVRLADTDLWIQVEKDFTVYGDEVKFGGGKVIRDGMGQSQLPSAKVMDLVITNALILDYWGIVKADIGIKNGRIAAIGKAGNPDVQPNVDIIVGPGTDVIAGEGSIITAGGIDSHIHFICPQQIDEALASGVTTMIGGGTGPTTGTNATTVTPGPWNMARMLEAADCFPMNLGFLGKGNASLPESLSEQISAGAIGLKLHEDWGTTPASIDNCLSVAEETDTQVAIHTDTLNESGFVEDTIAAFKDRTIHTYHTEGAGGGHAPDIIRAAGLANVLPSSTNPTRPYTVNTADEHLDMLMVCHHLDPSIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVVMRTWQTAHKMKVQRGSLKGDPSEHDNFRAKRYVAKYTINPALAHGMAHEIGSVEVGKLADLVLWSPAFFGVKPNLIIKGGMIAMAKMGDPNASIPTPQPVHYRPMFGAYGKARQATTMTFISQAAMDAGIPEQLTLANRIGVVKGCRTVKKKDMLLNDWLPHLEVDPQTYEVRADGQLLTCEPAEVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_ECO8A
Sequence: MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDLERVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_CHESB
Sequence: MSVPIFRTVKELRAAVADWRRDGLRVGVVPTMGALHEGHLSLVRAALANTDRVIVTLFVNPKQFNNAGDLAAYPRTEKEDAAKLAPLGAHMLYAPDGAEMYPNGFSTTVSVSGVSEGLCGAFRPGHFDGVATVVTKLLLQTGADLAFFGEKDFQQLHVVRRLTRDLDIPTQIIACPTVREADGLALSSRNVRLSADDRRNAPKLAEALFAAAGRLAEGTPVAEVLPNARDAILAAGYQEVEYLELRGEDDLAPLSGLDRPARLLVAAWIGGVRLIDNLPVAQPA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FH16_ORYSJ
Sequence: MAPAPSPTPLPLFLLLLLLVGVAPLAAAQGQNIQTRFPSTRTPAFATPPPITSPSPSPGTPTATPSSSPPSSSGKRSDIAVAVVSTALSSFAVSGLAFFLFLRHGKKRELTEAGGAGQHYGGAQGGALTGKRPEREPKRPARGNMVDENGLDAIYWREFEKEGDGGRGRKPPASRRPPQPPPPRPYRAERRQDAHESSAPSPPRSRKNRIDQEPLIPRGSLDSASAEFDESLYAPSAGSTSSFSVAAAEAYARPPSTPAITAVSSVPRSSPSPAPAPAARPASPSPSLPLPPGRESPSRPQSIAAAAVASPAPPPPPPPKPAAAAPPPPPPPKAAPPPPPPKGPPPPPPAKGPPPPPPPKGPSPPPPPPPGGKKGGPPPPPPKGGASRPPAAPGVPTGSADQQAKLKPLHWDKVNVAATDHSMVWDNITGGSFNLDEGIIEALFGTAAVNRKTKPADSKDASGGSTSAGLGRSNSPEQIFLLEPRKSHNISIILRSLTVGREEIIDALLNGHTELSTEVLEKLSRLNISKEEENTLLKFSGNPDRLAPAEFFLLRLLLDVPSPFARVNALLFKANYAAEVAQLKQSLRTLEMASQELRTKGLFFKLLEAVLKAGNRMNAGTARGNAQAFNLTALRKLSDVKSTDGSTTLLHFVIEEVVRSEGKRLAINRNYSLRRSGSLAKSTDGGNPAASSTSQGPSREERQNEYLNLGLPIVGGLSTEFANVKKAALVDYDTVVNECAILGNRLAGTKKLLETYGDDGFARGLRGFVKAAEQELNELKGNQEKVLELVQRTTEYYHTGATKDKNAHPLQLFIIVRDFLGMVDQACVDIKRKLQQQKKPTPPPSSSQPAAPAATTKGAADDAPAPAQKPPEEVDSKRKRVMPRFPNLPAHFMKDNADSDSSSDEE
What are the official names of this protein?
Formin-like protein 16, OsFH16.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-I subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SULA_ECO57
Sequence: MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: YBFQ_ECOLI
Sequence: MELKKLMEHISITPDYRQAWKVVHKLSDILLLTICAVISGAEGWEDIEDFGETHLDFLKQYGDFENGIPVHDTIARVVSQGKIT
What are the official names of this protein?
Inactive transposase YbfQ.
Protein: ASCA4_ASCTR
Sequence: GFKDWIKGAAKKLIKTVAANIANQ
What is the function of this protein?
Antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria.  Has a very week hemolytic activity (By similarity).
What are the official names of this protein?
Ascaphin-4.
What is the protein family that this protein belongs to?
Belongs to the ascaphin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTH_ACIBS
Sequence: MSNISLIVGLGNPGSEYAQTRHNAGFWFVEQLADKYGITLKNDPKFHGISGRGNIEGHDVRLLLPMTYMNRSGQSVVPFSKFYQIAPEAILIAHDELDMNPGVIRLKTGGGHGGHNGLRDIVPHIGPNFHRLRIGIGHPGSKERVSGHVLGKAPSSEQSLMDGAIDHALSKVKLLVQGQVPQAMNQINAYKPA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_CITBB
Sequence: MAKLDVFDIKKAKVGEIELDDAVFNDDVREYLIHEAVKIQLANRRQGTVAVKNRALVAGSGKKPFKQKGTGQARQGCRRAPQYPGGGVAFGPQPKDYNLSMNKKARKAALRSALSMLYKKDAITVVNSLELPSIKTKAFVEVLTAFNLDKTLVITDTATPTLELSARNVKHVKVLGPEGLNIFDIMKYQSVVFTEAAVRRVEGALQS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SSRP_LACLA
Sequence: MVKNTEDKPLAQNKKARHDYEIYETFEAGIVLTGTEIKSVRQAKIQLKDGFARVRNGEVWLSNVHIAPFEQGNIFNVEELRTRKLLLNKKEIAKIDKELSGTGITFIPLKVYLKNGFAKVLMGLARGKKDYDKRETLKRKEQNRDIARQIKAYNR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL18_STAHJ
Sequence: MISKIDKNKVRLKRHARVRTKLSGTAEKPRLNVYRSNKHIYAQIIDDVKGETLVQASSKDKDIASDSTSKVDLSTKVGEAIAKKASDKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GCH1_ECO55
Sequence: MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: YIDZ_SALPA
Sequence: MKKSLTSLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLAKLRAWFDDPLFVNTPLGLVPTPLMVSMEQSLADWMQMGNQLLDKPHHQTPRGLKFELAAESPLMMIMFNSLSQQIYQRYPQATIKVRNWDYDSLEAITRGEVDIGFTGRESHPRSRELLSLLPLAIDFEVLFSDLPWVWLREDHPALREAWDLDTFLRYPHISICWEQSDTWALDDVLQEMGRKRHIALSLPGFEQSLFMAAQPGHTLIATAPRYCQHYNQLHQLPLVARPLPFDAQQREKLMVPFTLLWHKRNSHNPKIVWLRQAINTLCRRLI
What is the function of this protein?
Involved in anaerobic NO protection.
What are the official names of this protein?
HTH-type transcriptional regulator YidZ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: CTIP_MOUSE
Sequence: MSISGSGCGSPNSADASNDFKELWTKLKEYHDKEVQGLQVKVTKLKKERILDAQRLEEFFTKNQQLRDQQKVLQETIKILEDRLRAGLCDRCAVTEEHMHKKQQEFENIRQQNLKLITELMNEKNTLQEENKKLSEQLQQKMENGQQDQVAELACEENIIPDSPVTSFSFSGINRLRKKENLHVRYVEQTHTKLERSLCTNELRKISKDSAPAPVNSEEHEILVADTCDQNHSPLSKICETSSYPTDKTSFNLDTVVAETLGLNGQEESEPQGPMSPLGSELYHCLKEDHKKHPFMESARSKEDSLRFSDSASKTPPQEFTTRASSPVFGATSTVKAHLGLNTSFSPSLLDIGKKNLLKTAPFSNIAVSRSEKVRSKSEDNALFTQHSLGSEVKVISQSFSSKQILTNKTVSDSVDEQCSADHMNTTVADKYLVPLKSLGGKASKRKRTEEESEHAVKCPQACFDKENALPFPMENQFSMNGDHVMDKPLDLSDRFAATQRQEKNHGNETSKNKLKQATIYEALKPIPKGSSSGRKALSGDCMPAKDSWETYCLQPRSLQSSSKFSPDQKTPLQIKEENPVFKTPPCSQESLETENLFGDVKGTGSLVPTKVKSRAVHGGCELASVLQLNPCRVAKTKALPSNQDTSFENIQWSVDPGADLSQYKMDVTVIDTKDSSHSRLGGETVDMDCTLVSETVLLKMKKQEQKERSPNGDIKMNDSLEDMFDRTTHEEYESCLADSFSQVPDEEELPDTTKKTNIPADKQDGVKQKAFVGPYFKDKERETSIQNFPHIEVVRKKEERRKLLGHTCKECEIYYADLPAEEREKKLASCSRHRFRYIPPNTPENFWEVGFPSTQTCLERGYIKEDLDLSPRPKRRQPYNAVFSPKGKEQRT
What is the function of this protein?
Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway (By similarity).  HR is restricted to S and G2 phases of the cell cycle and preferentially repairs DSBs resulting from replication fork collapse (By similarity).  Key determinant of DSB repair pathway choice, as it commits cells to HR by preventing classical non-homologous end-joining (NHEJ) (By similarity).  Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA (By similarity).  Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage (By similarity).  During immunoglobulin heavy chain class-switch recombination, promotes microhomology-mediated alternative end joining (A-NHEJ) and plays an essential role in chromosomal translocations (PubMed:21131978, PubMed:21131982).
What are the official names of this protein?
DNA endonuclease RBBP8, CtBP-interacting protein, CtIP, Retinoblastoma-binding protein 8, RBBP-8, Retinoblastoma-interacting protein and myosin-like, RIM, Sporulation in the absence of SPO11 protein 2 homolog, SAE2.
What is the protein family that this protein belongs to?
Belongs to the COM1/SAE2/CtIP family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with sites of DNA damage in S/G2 phase. Ubiquitinated RBBP8 binds to chromatin following DNA damage.
Protein: PURA_STAAN
Sequence: MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELDGLNERGIPTSNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLKSNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVSGITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERISELCNVQISIFSVGPDREQTNLLKELW
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT2_ARATH
Sequence: MGIISTILGVIGFGFGTTIGIVIGYYLFIYFQSTDVEDPEIKPLVELDSETIATMFPEIPMWVKNPDFDRIDWLNKLIGHMWPYMDKAICKMAKSIAKPIIAEQIPNYKIDSVEFEMLTLGSLPPSFQGMKVYATDDKEIIMELSVKWAGNPNIIVVAKAFGLKATVQVIDLQVYATPRITLKPLVPSFPCFANIFVSLMDKPQVDFGLKLLGADVMAIPGLYRFVQEIIKDQVANMYLWPKTLNVQIMDPSKAMKKPVGLLSVKVIKAIKLKKKDLLGGSDPYVKLTLSGDKVPGKKTVVKHSNLNPEWNEEFDLVVKEPESQELQLIVYDWEQVGKHDKIGMNVIQLKDLTPEEPKLMTLELLKSMEPKEPVSEKSRGQLVVEVEYKPFKDDDIPENIDDPNAVEKAPEGTPSTGGLLVVIVHEAEDLEGKYHTNPSVRLLFRGEERKTKRVKKNREPRWDEDFQFPLDEPPINDKLHVEVISSSSRLIHPKETLGYVVINLGDVVSNRRINDKYHLIDSKNGRIQIELQWRNSS
What is the function of this protein?
May play an important role in regulating an unconventional protein trafficking from the cytosol to the extracellular matrix.
What are the official names of this protein?
Synaptotagmin-2, NTMC2T1.2, Synaptotagmin B.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass membrane protein.
Protein: AROC_PSEA7
Sequence: MSGNTYGKLFTVTSAGESHGPALVAIVDGCPPGLELSAQDLQRDLDRRKPGTSRHTTQRQEADEVEILSGVFEGRTTGTPIGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLAGLGIRVRGYMSQLGPIEIPFKTWDSVERNAFFSPDPDKVPELEAYMDQLRRDQDSIGAKITVVAEGVPPGLGEPIFDRLDAELAHALMSINAVKGVEIGAGFASIAQRGTEHRDELTPQGFLSNNAGGILGGISSGQPIVAHLALKPTSSITTPGRSIDTAGEPVDMITKGRHDPCVGIRATPIAEAMMAIVLLDQLLRQRGQNADVRVDTPILPQL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ANFC_SQUAC
Sequence: MSGHTSFYCGLLLLLLIQVQARPRADDSLQVLSRLLEDEYGHFNSEELNNEAQEISPAASLPDLNTDQSDLELPWDRESREIGGRSFRQEALLARLLQDLSNNPLRFKGRSKKGPSRSCFGLKLDRIGAMSGLGC
What is the function of this protein?
Hormone which may be vasoactive and natriuretic.  Has a cGMP-stimulating activity (By similarity).
What are the official names of this protein?
C-type natriuretic peptide.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARLY_LEUMM
Sequence: MSDKLWGGRFTAKAAEWVDEFGASIHFDQKMAAEDIEGSIAHAKMLGKQGIISPEESEKIVSGLKIINEELIAGKIEFDVKNEDIHMNIESLLTEKIGPVAGKLHTARSRNDQVATDFHLWVKHRLPHVLESLTELQEELLTLATTHAGTIMSGYTHLQHAQPITYGHYLLAYFEMFQRDYERFEFNQKHTDILPLGAAALAGTTFPIDREFVASELGFDSIYHNSLDAVSDRDFALEFLSNAAILMMHLSRMAEELILWSTYEFNYIELSDDFSTGSSIMPQKKNADFAELVRGKTGRSYGALMGLLTTMKSLPLAYNKDMQEDKEQVFDIMDTVLASVKVFTGMLSGLTVHKERMLATTQDDFSNATELADYLATKGVPFREAHAIVGQLVLTGIQSKTPLQKMSLSDLQAVAPQIEEDIYDKLQSETAVNRRTSLGGTAVENVKKEIVRNKKVLEAR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECCA1_MYCTO
Sequence: MTDRLASLFESAVSMLPMSEARSLDLFTEITNYDESACDAWIGRIRCGDTDRVTLFRAWYSRRNFGQLSGSVQISMSTLNARIAIGGLYGDITYPVTSPLAITMGFAACEAAQGNYADAMEALEAAPVAGSEHLVAWMKAVVYGAAERWTDVIDQVKSAGKWPDKFLAGAAGVAHGVAAANLALFTEAERRLTEANDSPAGEACARAIAWYLAMARRSQGNESAAVALLEWLQTTHPEPKVAAALKDPSYRLKTTTAEQIASRADPWDPGSVVTDNSGRERLLAEAQAELDRQIGLTRVKNQIERYRAATLMARVRAAKGMKVAQPSKHMIFTGPPGTGKTTIARVVANILAGLGVIAEPKLVETSRKDFVAEYEGQSAVKTAKTIDQALGGVLFIDEAYALVQERDGRTDPFGQEALDTLLARMENDRDRLVVIIAGYSSDIDRLLETNEGLRSRFATRIEFDTYSPEELLEIANVIAAADDSALTAEAAENFLQAAKQLEQRMLRGRRALDVAGNGRYARQLVEASEQCRDMRLAQVLDIDTLDEDRLREINGSDMAEAIAAVHAHLNMRE
What is the function of this protein?
Part of the ESX-1 specialized secretion system, which delivers several virulence factors to host cells during infection, including the key virulence factors EsxA (ESAT-6) and EsxB (CFP-10).  EccA1 exhibits ATPase activity and may provide energy for the export of ESX-1 substrates.
What are the official names of this protein?
ESX-1 secretion system protein EccA1, ESX conserved component A1, Type VII secretion system protein EccA1, T7SS protein EccA1.
What is the protein family that this protein belongs to?
Belongs to the CbxX/CfxQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1764_SHEPA
Sequence: MAIQSKYSNAQVESIIAELLAVLEKHQSPTDLSLMALGNCVTHLLQKKVPAEAREVVAEQFAKALSRSVKS
What are the official names of this protein?
UPF0352 protein Spea_1764.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: AROB_MYCPA
Sequence: MRTTREPVTVQVAVDPPYPVIIGTGLLGELDELLGARHKVAVVHQPVLAETAEVIRKRLADKGVDAHRIEIPDAEDGKDLPVVGFLWEVLGRIGIGRKDALVSLGGGAATDVAGFAAATWLRGVDIVHVPTTLLGMVDAAVGGKTGINTDAGKNLVGAFHQPLAVLVDLATLHTLPPNELVAGMAEVVKAGFIADPAILDLIEADPRAAVDPSGEVLAELVQRAIAVKADVVAADEKESELREILNYGHTLGHAIERRERYRWRHGAAVSVGLVFAAELARLAGRLDDATARRHRTILSALGLPVSYDADALPQLLEYMAGDKKSRAGVLRFVVLDGLAKPGRLAGPDPSLLAAAYAALADEDAS
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB3_BRUME
Sequence: MRNWRQAENIRLYIAVGCGAAIGALLRFLSGWVIVAILGANPLWGTSFVNIVGSFIIMFFATLTGPEGRWLVSPALRQFVMGGLCGGLTTFSSMSLDTFLLVLHGNAAFALAYLCGLVFLSLSAAMLGLIAAQRINR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 3.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEXA_YERPP
Sequence: MKALTTRQQEVYDLVRDHLAQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLMEEEEGLPLIGRVAAGEPLLAQQHIEGHYKVDPSLFKPGADFLLRVNGMSMRDIGILDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNIVHLLPENSEFQPIVVDLREQSFTIEGLAVGVIRNGDWI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.