PharMolix/UniProtQA huggingface dataset:
Protein: AP3B2_MOUSE
Sequence: MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAATAALPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPKIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPILESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSEPESESESESKSSSGSGSGESSSESDNEEEDEEKGGGSESEQSEEEDEKKKKTKKKKASEGHREGSSSEEGSDSSSSSESEVTSESEEEQVEPASWRKKTPPGSKSAPVAKEISLLDLEDFTPPSVQPVSPPMVVSTSLAADLEGLTLTDSSLVPSLLSPVSSIGRQELLHRVAGEGLSVDYAFSRQPFSGDPHMVSLHIYFSNNSETPIKGLHVGTPKLPAGISIQEFPEIESLAPGESTTTVMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLTGMNEITEKLTLPDTCRSDHMVVQKVTATANLGRVPCGTSDEYRFAGRTLTSGSLVLLTLDARAAGAAQLTVNSEKMVIGTMLVKDVIQALTQ
What is the function of this protein?
Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes.  The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.  AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles.  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
What are the official names of this protein?
AP-3 complex subunit beta-2, Adaptor protein complex AP-3 subunit beta-2, Adaptor-related protein complex 3 subunit beta-2, Beta-3B-adaptin, Clathrin assembly protein complex 3 beta-2 large chain.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: NDHK_SOLBU
Sequence: MNSIQFPLLDRTAPNSVISTTLNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQSDLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKISRELYEDRIRSQRANRCFTTNHKFHVRRSIHTGNYDQRVLYQPPSTSEIPTEIFFKYKNSVSSAELVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: TX15_GRAPO
Sequence: DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF
What is the function of this protein?
Potent voltage-gated sodium channel blocker (PubMed:25658507).  Potently inhibits the voltage-gated sodium channels Nav1. 7/SCN9A (IC(50)=0. 58-10 nM) (PubMed:25658507, PubMed:26999206).  Also shows a moderate activity on Nav1. 1/SCN1A (IC(50)=6 nM), Nav1. 2/SCN2A (IC(50)=5-128 nM), Nav1. 3/SCN3A (IC(50)=20. 3-170 nM), and Nav1. 6/SCN8A (IC(50)=17-20. 1 nM) (PubMed:25658507, PubMed:26999206).  Shows an unclear inhibition of Nav1. 4/SCN4A (IC(50)=200 nM to >10 uM), Nav1. 5/SCN5A (IC(50)=140 nM to >10 uM) and Nav1. 8/SCN10A (IC(50)=68-12200 nM) (PubMed:25658507, PubMed:26999206).  Weakly blocks the low voltage-gated calcium channels Cav3. 1/CACNA1G (30% inhibition of the peak current at 9. 8 nM) (By similarity).  shows moderate affinity for lipid bilayers (By similarity).  In vivo, when tested on the OD1-induced mouse model of Nav1. 7/SCN9A-mediated pain, the toxin is effective when co-administered with OD1, but lacks efficacy when delivered systemically (PubMed:26999206).
What are the official names of this protein?
Toxin GTx1-15, Beta/omega-theraphotoxin-Gr2a, Beta/omega-TRTX-Gr2a, Toxin GpTx-1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 08 (Gtx1-15) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CEL3B_MOUSE
Sequence: MLRLLSSLLLVALASGCGQPSHNPSSRVVNGEEAVPHSWPWQVSLQYEKDGSFHHTCGGSLITPDWVLTAGHCISTSRTYQVVLGEHERGVEEGQEQVIPINAGDLFVHPKWNSMCVSCGNDIALVKLSRSAQLGDAVQLACLPPAGEILPNGAPCYISGWGRLSTNGPLPDKLQQALLPVVDYEHCSRWNWWGLSVKTTMVCAGGDIQSGCNGDSGGPLNCPADNGTWQVHGVTSFVSSLGCNTLRKPTVFTRVSAFIDWIEETIANN
What is the function of this protein?
Efficient protease with alanine specificity but only little elastolytic activity.
What are the official names of this protein?
Chymotrypsin-like elastase family member 3B, Elastase IIIB, Elastase-3B, Protease E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Elastase subfamily.
Protein: NIFD_RHICP
Sequence: MSLASTQSIAEIRARNKELIQEVLKVYPEKTAKRRAKHLNVHQAGKSDCGVKSNIKSIPGVMTIRGCAYAGSKGVVWGPIKDMVHISHGPVGCGQYSWGSRRNYYVGTTGIDSFVTLQFTFDFREKDIVFGGDKKLVKILDEIQELFPLNNGITIQSECPIGLIGDDIEAVSRAKSKEYGGKTIVPVRCEGFRGVSQSLGHHIANDAVRDWIFDQVEADGKPKVEPTPYDVAIIGDYNIGGDAWSSRILLEEMGLRVIAQWSGDGSLAELEANVEGKLNILHCYRSMNYISRHMEEKFGIPWCEYNFFGPSKIAESLRRIAGYFDDKIKEGAERVIEKYQPLVNAVIAKYRPRLEGKTVMLYVGGLRSRHVIGAYEDLGMEVIGTGYEFGHNDDYQRTAQHYVKDGTLIHDDVNGYEFERFVEKLQPDLVGSGIKEKYVFQKMGGPFRQMHSWDYSGPYHGYDGFAIFARDMDMAINSPVWKKTKAPWKEASRAKLLAAE
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein alpha chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: MURC_SHEWM
Sequence: MGNDKEKYSKLRNIIPEMRRVKHIYFVGIGGAGMGGIAEVLVNEGYRLSGSDIAENAVTQRLASLGAKIHLGHKEEQVHGADVVVVSTAIHADNPELLEAQALRIPVVRRAEMLAELMRYRHGVAVAGTHGKTTTTSLIASVYGQAERDPTFVIGGLLNSAGTNARLGNSRYLIAEADESDASFLHLQPMVSVITNIEADHMDTYEGDFERLKSTFIDFLHNLPFYGIAVMCIDDPVVRELLPSVGRKIVTYGFSEDADVQALNFVQDGYRSRFTLRRTGVEDVEVMVNLPGEHNVLNALAAIAVASEDEIEDEAIIQALADFEGIGRRFEQLGCFDTDRGEVVLVDDYGHHPSEVAATIKAAKLGWPEKRLVMIYQPHRYSRTRDLYEDFVEVLSQVDCLLLLDVYSAGEAAIPGADSRALCRSIRLRGQLDPIFVADQEQLLTLLPDVLQEGDLLLTQGAGNIGALARQLAQNRLGFESTNNDSNRG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSE1_NICBE
Sequence: MSKRPAPDPVSVLRGHRASVADICFHPSNSILFSGSTDGELRIWNTVQYRTVSSAWVHSAAHGIICVAASPVLGDNKVISQGRDGTVKCWDFGGGGLSRTPLLTIKTNSYHFCKLSIAKSPSEAMKIDDLEVNEIVDGMQREEQGDQPTDSIKFKGKELIEGPKYVAIAGEQASVVEIWDVNTAERIAQLPHSSGSPSNQTPNQRGMCMAVQAFLPSESQGLLSIMAGYEDGSIAWWDLRNLGVPLTSVKFHSEPVLSLCIDGSCKGGLSGAADEKILMFALDHSMGSCLIRKEIVLERPGIAGTSIRPDGKIAATAGWDHRVRIYNYRKGKPLAILKYHNATCNTVSFSADSKLLASASEDTTVALWELYLPRT
What is the function of this protein?
Involved in the formation of X-, Y-shaped and twinned plasmodesmata (PD), thus modelating PD size exclusion limit and regulating cell-to-cell transport (PubMed:22411811).  Cell cycle checkpoint regulator that monitors and responds to DNA damage such as DNA cross-links, and triggers the halt of the cell cycle progression in the presence of DNA cross-linking agents.  Mediates the active process of aluminum- (Al) dependent root growth inhibition and thus is required for response to Al toxicity.  Essential for signal transduction and development of both male and female organs (By similarity).
What are the official names of this protein?
Protein DECREASED SIZE EXCLUSION LIMIT 1, NbDSE1.
What is the protein family that this protein belongs to?
Belongs to the plant DSE1 protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LAP1_TRIEQ
Sequence: MKLLSVLALSATATSVLGASIPVDTRAQKFLIELAPGETRWVTEEEKWELKQKGQDFFDITDEEVGFTAAVAQPAIAYPTSIRHADAVNAMIATLSKENMQRDLTKLSSFHNRYYKSDYGKQSATWLQQQVQAVINSSGASRYGAKVVSVRHNFVQHSIVATIPGRSPEIVVVGAHQDSINQRSPMTGRAPGADDNGSGSVTILEALRGVLQDQTIVQGKAANTIEFHWYAGEEAGLLGSQAIFANYKQTGKKVKGMLNQDMTGYIKGMVDRGLKVSFGIITDNVSTSLTSFIRMVITKYCSIPTIDTRCGYACSDHASANRNGYPSAMVAESPINLLDPHLHTDSDLISYLDFDHMIEHAKLVVGFVTELAK
What is the function of this protein?
Extracellular aminopeptidase which contributes to pathogenicity.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MDM34_SCLS1
Sequence: MAFNFNWSPLTADAEFYQRAQEMLTAALNKSPKPPIIKDDILVNELNLGSVPPDLEILEIGDLAEDRFRGIFKMCYSGDAFLTLKTRVQANPLNNHLFSKPSFTSPQPLAADAGLTIPLQITLSEIKLSAFIIVVFSKQKGLTLVFRNDPLESLKVSSTFDSIPFIKDYLQKEIEQQLRTLMMDELPAIIHRLSLRLWCPEYRGKEDQEMAEAVKKTKDEVAIDPFASPPQDAVDARGNVLDASEISNLSLDGGSEIHSLFSQKNLLRLAALTNSHRTLSLFTPSIRDAVFRAWAPSERGDSAGTTTPATTSLHRPQSSLGGQSTTYTFSNRSSDDGHGSMPSRPSLVNMNSATTGLSLGANRGSRSHTTRKKKNRVVNLRKSKTTDNVSESGESETASITAASEPIVQSRIPEEPEDIPVTPPPGKVRFNSIDLGDSPKKLQPSRSITPEQGNMNQIPTLTVEPSTPIHSENQKRPAYNQSSFTSYTSEKSATTPPHTQFSYPHGLHFSATESPSGILEQAWIMKMASELARRRHDKTAREGFWSTSSNGDDAPPAYEPKAL
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: PSD_ALKEH
Sequence: MSVYRDESPATGLDHLKAALLYPLPHHAISRMVHWAVRVETPWFKNLLIKAFIRVFKVDMSEALEEDPTAYPTFNAFFTRALKPEARPLPDDPDAILSPADGTISQMGPIERDTIFQAKGHSFTTAELLGGDEALAEEFRDGWFATIYLSPRDYHRVHMPMTGTLRQMIHIPGRLFSVAPFTVRTVPKLFARNERVACIFDTDRGPMAVVLVGAINVGSIETVWAGEITPPAGIRAQYSNYEADNAPTIARGHEMGRFNMGSTVITLQNSRPAPGKIMSAHIKQGMTI
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PRAF3_MOUSE
Sequence: MDVNLAPLRAWDDFFPGSDRFARPDFRDISKWNNRVVSNLLYYQTNYLVVAAMMISVVGFLSPFNMILGGVIVVLVFMGFVWAAHNKDILRRMKKQYPTAFVMVVMLASYFLISMFGGVMVFVFGITLPLLLMFIHASLRLRNLKNKLENKMEGIGLKKTPMGIILDALEQQEDNINKFADYISKARE
What is the function of this protein?
Regulates intracellular concentrations of taurine and glutamate (By similarity).  Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner (PubMed:12119102, PubMed:18684713).  Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum (By similarity).
What are the official names of this protein?
PRA1 family protein 3, ADP-ribosylation factor-like protein 6-interacting protein 5, ARL-6-interacting protein 5, Aip-5, Addicsin, GTRAP3-18, Glutamate transporter EAAC1-interacting protein, Prenylated Rab acceptor protein 2, Protein JWa.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton. Note=Also exists as a soluble form in the cytoplasm. Associated with microtubules.
Protein: CRVP_DABRR
Sequence: SVDFDSESPR
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein, CRVP, Cysteine-rich secretory protein, CRISP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACYP_FERNB
Sequence: MLEVWKKWNVRGVVQGVGFRHFVKNVARAIGVRGYVKNEDDGSVTIVAGGNDEQIKELFRRIMEGNGWSYISDYDEIDLPKQEYKDFHVEF
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: MURC_DESAH
Sequence: MYQKNYHIYFVGIGGIGMSAIAELLLSLGYRVSGSDLKLSAITQRLASCGATIFNGHRADQVKDVDVLVTSTAISKNNPEVIEAAERSIRTIPRAEMLAELMRIKYAIAVSGAHGKTSTTAMIATILNQAGLDPTVVVGGLLKSIGTNAHHGKGDYIVAEADESDGSFLKYAPAIAAVTNIDLEHLDFYKDIEDIKDNFVKFINSVPFYGLAVLCLDNEHIQAILPRITARYTTFGLSAQADLAARGIRFEGRRGYFTVVHGKEVLGDITLNLSGKHNISNALAAIAVALELKVDFSVIKEALEQIEGVKRRLEIKGERNSITVVDDYGHHPTEVKTTLAAVREGWPDKRVVVVFQPHRYSRTKALFDEFTRAFYQSDLLFVLPIYAASEQPIDGIDSLKLCNGIQEHGHKNVICVKDFESCLSILSDTLEPGDLVLTLGAGDVYNLGETLLEILA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_I77AG
Sequence: MLSVVILFLLVAENSSQSYTGNPVICMGHHSVANGTMVKTLTDDQVEVVTARELVESQTLPELCPSPLRLVDGQTCDIINGALGSPGCDHLNGAEWDVFIERPNAVDTCYPFDVPDYQSLRSILANNGKFEFIAEEFQWNTVIQNGKSSACKRANVNDFFNRLNWLVKSTGNAYPLQNLTKVNNGDYARLYIWGVHHPSTDTEQTNLYKNNPGRVTVSTKTSQTSVVPNIGSRPLVRGQSGRISFYWTIVEPGDLIVFNTIGNLIAPRGHYKLNNQKKSTILNTPIPIGSCVSKCHTDKGSVSTTNPFQNISRIAIGECPKYVKQGSLKLATGMRNVPEKASRGLFGAIAGFIENGWQGLIDGWYGFRHQNAEGTGTAADLKSTQAAIDKINGKLNRLIEKTNEKYHQIEKEFNKIEGRVQDLEKYVEDTKIDLWSYNAELLVALENQHTIDVTDSEMNKLFERVRRQLRENAEDQGNGCFEIFHKCDNNCIESIRNGTYDHDIYRDEAINNRFQIQGVKLIQGYKDIILWISFSISCFLLVALLLAFILWACQNGNIRCQICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RL41_ICTPU
Sequence: MRAKWRKKRMRGLKRKRRKMRQRSK
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL41 family.
Protein: PGK_MALP2
Sequence: MEYNKKIVTDLTDLKGKKVILRCDFNVPINKTSGEITDYTRIDAALQTINYLLDKGVKLIVLSHLSRVKTLEDISSGKKSLKVVHKALKNRLLGKTVLFEENNRNKDLPKIIDGMEEGSLLLLENTRYADVNEKGEVVKLESKNDPSLGKFWASLADIFVNDAFGTSHRAHASNVGIAKNIKESAIGFLVNKELAKLSKAVVNPRKPVVAIFGGAKVSDKVPSIKNIGKFADKILIGGGMAFIFLKAKGFEIGKSLYEDDQLELTKELLSEFGNKIVLPVDAVVADSIKAAKGKRYDMEQFPADLAGFDVGKKTIKLFKKELKLAETVIWNGPLGVFENDAFNKGTLKVCKYIAKITAKKGCYSVIGGGDSAAAAAKCGVTHSFSHISTGGGASLEFFSGVELPGVACIKNKGEEGKVEAVKEKTTTTTESASKEKSSTAKTASKPATSKTTAAKKPAEKKPAAKKPAAKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_ECO81
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ENO_PARDP
Sequence: MTAIIDIFAREILDSRGNPTVEVDVTLEDGTMGRAAVPSGASTGAHEAVEKRDGDKARYLGKGVLEAVAAVNGEIAENLIGEDATEQVAIDRMMIELDGTPNKGRLGANAILGVSLAVAKAAAEACSQPLYRYVGGAGARVLPVPMMNIINGGEHADNPIDIQEFMIMPVAAENIREAVRMGSEVFHTLKKELSSAGLATGVGDEGGFAPNLSSTRDALDFILKAIEKAGYQPGDDIMLALDCASTEYFKGGKYEMAGEGKSLSPAENVAYLEALCNDYPILSIEDGCAEDDWDGWKLLTDTLGGRVQLVGDDLFVTNPARLAEGIAKGCGNSLLVKVNQIGTLTETLDAVRMADRARYTSVMSHRSGETEDATIADLAVATNCGQIKTGSLARSDRLAKYNQLIRIEEMLGATAEYAGKSILRG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SWEET_VIBSN
Sequence: MALIERIGKALEPLMLVMGLISPLATMPQLYKLYVSHSEHALGLSLTTWLLYSFIALLWTIYGIYHKNPTIWVGNCLGFLMYVAMVVGIIAHTGGTY
What is the function of this protein?
The homodimer mediates transmembrane sugar transport down a concentration gradient.  Transport is probably effected by rocking-type movements, where a cargo-binding cavity opens first on one and then on the other side of the membrane.
What are the official names of this protein?
Sugar transporter SemiSWEET.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECJ_ECOLI
Sequence: MKQQIQLRRREVDETADLPAELPPLLRRLYASRGVRSAQELERSVKGMLPWQQLSGVEKAVEILYNAFREGTRIIVVGDFDADGATSTALSVLAMRSLGCSNIDYLVPNRFEDGYGLSPEVVDQAHARGAQLIVTVDNGISSHAGVEHARSLGIPVIVTDHHLPGDTLPAAEAIINPNLRDCNFPSKSLAGVGVAFYLMLALRTFLRDQGWFDERNIAIPNLAELLDLVALGTVADVVPLDANNRILTWQGMSRIRAGKCRPGIKALLEVANRDAQKLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNIGEARVLANELDALNQTRKEIEQGMQIEALTLCEKLERSRDTLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAGDGTLKGSGRSIQGLHMRDALERLDTLYPGMMLKFGGHAMAAGLSLEEDKFKLFQQRFGELVTEWLDPSLLQGEVVSDGPLSPAEMTMEVAQLLRDAGPWGQMFPEPLFDGHFRLLQQRLVGERHLKVMVEPVGGGPLLDGIAFNVDTALWPDNGVREVQLAYKLDINEFRGNRSLQIIIDNIWPI
What is the function of this protein?
Single-stranded-DNA-specific exonuclease.  Required for many types of recombinational events, although the stringency of the requirement for RecJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available.
What are the official names of this protein?
Single-stranded-DNA-specific exonuclease RecJ.
What is the protein family that this protein belongs to?
Belongs to the RecJ family.
Protein: ATPA_BACP3
Sequence: MSIRAEEISALIKQQIENYESQIQVSDVGTVIQVGDGIARAHGLDNVMSGEAVEFANAVMGMALNLEENNVGIVILGPYTGIKEGDEVRRTGRIMEVPVGETLIGRVVNPLGQPVDGLGPVETTETRPIESRAPGVMDRRSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTSVAIDTIINQKDQNMICIYVAIGQKESTVATVVETLAKHGAPDYTIVVTASASQPAPLLFLAPYAGVAMGEYFMIMGKHVLVVIDDLSKQAAAYRQLSLLLRRPPGREAYPGDIFYLHSRLLERAAKLSDAKGGGSLTALPFVETQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGAAQIKAMKKVAGTLRLDLAAYRELEAFAQFGSDLDKATQANVARGARTVEVLKQDLHQPIPVEKQVLIIYALTRGFLDDIPVEDVRRFEKEFYLWLDQNGQHLLEHIRTTKDLPNEDDLNQAIEAFKKTFVVSQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GRPE_LEPCP
Sequence: MPDTPKADIPSDNAALEAQGIASELIDDSAARIAELEAKNADLADAYLRAKAEADNIRRRADDDIAKSRKFAVESFAESLLPVKDSLEAAIVSHAAGKGSPEQVIEGVHATLRQLGQALERNKVLEVNPPAGTKFDPHQHQAISVVPAEQEANTVVAVLQKGYLIADRVLRPALVTVAAAK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_DELAS
Sequence: MSAALPITAVPACASGWQAMLDLRFGHRAGQGSVLSHARHSGPLRVQKPLHPEGPGICHAVLLHPPGGVAGGDQLQIDVTVEPGAHALLTTPGATRWYKSQGRPAAQRVRLRVEEGAILEWLPQENMLFAGADATMALDLDLAPGARAIGWDAVVLGRYGAGEHWNHTGAAPTAAARLQLHNRLACGGRPLWLEQGELHAGHALLSSPVAWAGLPIQASLWAVAPEPLAAMEPLSEQLAASLPWSDEVRAGASLLAGQGGAPSVLLLRVLARRMEAARAVLHEGWRLLRPALLNQQARPPRLWAT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.