PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_ECOLU
Sequence: MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GLK_NEIG2
Sequence: MSSTPNKHADYPRLVADIGGTNARFALETAPCVIEKVAVLPCKEYDTVTDAVRAYLNQSGATGVRHAAFAIANPILGDWVQMTNHHWAFSIETTRQALGLDTLILLNDFTAQALAVTQTSSKDLMQVGGQKPVEFAPKAVIGPGTGLGVSGLVHSPAGWVALAGEGGHTSFPPFDDMEVLIWQYAKNKYRHVSAERFLSGAGLSLIYETLAAKQKAEPAKLMPSEITEKALNCESPLCRQALDIFCAMLGTVASNLALTLGARGGVYLCGGIIPRMLDYFKTSPFRSRFENKGRFEAYLAAIPVYVVLSEFPGIAGAAAALGNHLKNV
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_BUXMI
Sequence: MIRDGNEEMSTIPGFSQIQFEGFCRFIDQGLMEELYKFPKIEDTDQEIEFQLFVETYQLAEPLIKERDAVYESLTYSSELYVPAGLIWKTSRNMQEQTIFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELDHNGTSVYTGTIISDWGGRSELEIDRKARIWARVSRKQKISILVLSSAMGSNLREILDNVCYPEIFLSFPNDKEKKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNRRLNLDIPQNNTFLLPRDILAAADRLIGIKFGMGTLDDMNHLKNKRIRSVADLLQDQFGLALVRLENAVRGTICGAIRHKLIPTPQNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKSSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGHWGSLESPFYEISERSKKVRMLYLSPSKDEYYMVAAGNSLSLNKGIQEEQVVPARYRQEFLTIAWEQVHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGVSAIAEHEGKIIYTDIDKIILSGNGDTLRIPLVMYQRSNKNTCMHQKPQVQRGKCIKKGQILADGAATVGGELALGKNVLVAYMPWEGYNSEDAVLISECLVYRDIYTSFHIRKYEIQTHVTSQGPERITNEIPHLEAHLLRNLDKNGIVMLGSWVETGDILVGKLTPQTSKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRVIDVRWIQKKGGSNYNPETIRVYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQNGTPVDMVFNPLGVPSRMNVGQIFECSLGLAGGLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGKSYIMKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPNPEDTPESFRLLVRELRSLALELNHFLVSEKNFQINRKAA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS15_YEREN
Sequence: MSLSVEAKAKIVADFGRDANDTGSSEVQVALLTAQINHLQGHFSEHKKDHHSRRGLLRMVSTRRKLLDYLKRKDVASYVSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RL29_METPP
Sequence: MKASELRAKDVAALEQEVKDLLKAHFGLRMQKGTQQLGNTASLRLTRRDIARAKTILAEKKKGAAQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ASTD_SALA4
Sequence: MTLWINGDWITGQGERRRKTNPVSAEILWQGNDANAAQVAEACQAAREAFPRWARQPFAARQAIVEKFAALLEAHKADLTEVIARETGKPRWEAATEVTAMINKIAISIKAYHARTGEQKSELVDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTLIFKPSELTPWTGETVIKLWERAGLPAGVLNLVQGGREIGQALSSLDDLDGLLFTGSASTGYQLHRQLSGQPEKILALEMGGNNPLIIEDATNMDAAVHLTLQSAFITAGQRCTCARRLLVKQGAQGDAFLARLVDVAGRLQPGRWDDDPQPFIGGLISAQAAQHVMEAWRQREALGGRTLLAPRKVKEGTSLLTPGIIELTGVADVPDEEVFGPLLNVWRYAHFDEAIRLANNTRFGLSCGLVSTDRAQFEQLLLEARAGIVNWNKPLTGAASTAPFGGVGASGNHRPSAWYAADYCAWPMASLESPELTLPATLSPGLDFSRREAV
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: AROC_HYPNA
Sequence: MSHNTFGHLFRVTTWGESHGPALGCVIDGCPPGLSLDAPFIQQFLDKRRPGTSRFVTQRQEADEVKILSGVFEDDRTDGPVTTGTPISLMIENTDQRSKDYREIRDRYRPGHADYAYDQKYGVRDYRGGGRSSARETAARVAAGAVARRVLGEDILLRGAVVQIGPHMIDPKNWDWAETQNNPFWCPDAKMAAQWETYLDSVRKSGSSTGAIVEVHASGVPAGWGAPVYGKLDAELAGAMMSINAAKGVEIGAGFAAASMSGEENADEMRAGNDAPRFLANNNGGVAGGISTGQDIVVRIAIKPTSSILNEVKSITRDGEEVDVRTIGRHDPCVGIRAVPVAEAMLACVLADAKLRHRGQTGH
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ASB16_HUMAN
Sequence: MARETFPFTSSMLRSLRLQQEWLEWEDRRRAAAQQCRSRRCPSSPRARLTRPHRSCRDPAVHQALFSGNLQQVQALFQDEEAANMIVETVSNQLAWSAEQGFWVLTPKTKQTAPLAIATARGYTDCARHLIRQGAELDARVGGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNTACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNACANGCGGLAELLLRYGARAEVPNGAGHTPMDCALQAVQDSPNWEPEVLFAALLDYGAQPVRPEMLKHCANFPRALEVLLNAYPCVPSCETWVEAVLPELWKEHEAFYSSALCMVNQPRQLQHLARLAVRARLGSRCRQGATRLPLPPLLRDYLLLRVEGCIQ
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 16, ASB-16.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: Y791_METB6
Sequence: MQFNPGPPAGFHAPPAKQKACTVTFFLFTPDILNYIVLPVLIFLAQIANVCMETLRIVFLSKGMKYLAPVIAFFEIIIWLLAIVGVLNNLSNIAYFLAYAFGFALGTYVGLVIEEKLSIGMVIMRIITTDGSGDGITEYLQQENYGTTCLDAKGARGGVKMIISLVNRDDVPRITRHIEETNPGAFFSIEDVRYVNQGVFRPKKQNPFTGFIHTLARPRKRV
What are the official names of this protein?
UPF0316 protein Mboo_0791.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CML47_ARATH
Sequence: MEDSSLLSPISLLTIVIFLFILNLMMIIQDFSSSFPFRFHLFFSNAYILFTSIRNNKQNTELPIIKKVVVPNRADIKTSVEEVKAIIDDSEALYECLIEEGEEYLLEKNEMMGKEIVKEAFRLFDENQDGFIDENELKHVLSLLGYDECTKMECRKMVKVYDENRDGKIDFYEFVKLIEKSFS
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML47, Calmodulin-like protein 47.
Protein: SIA8B_MOUSE
Sequence: MQLQFRSWMLAALTLLVVFLIFADISEIEEEIGNSGGRGTIRSAVNSLHSKSNRAEVVINGSSPPAVADRSNESLKHNIQPASSKWRHNQTLSLRIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDSTMNVSQNLYELLPRTSPLKNKHFQTCAIVGNSGVLLNSGCGQEIDTHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRAFEDLVNATWREKLLQRLHGLNGSILWIPAFMARGGKERVEWVNALILKHHVNVRTAYPSLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCNQIYLYGFWPFPLDQNQNPVKYHYYDSLKYGYTSQASPHTMPLEFKALKSLHEQGALKLTVGQCDGAT
What is the function of this protein?
May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.
What are the official names of this protein?
Alpha-2,8-sialyltransferase 8B, Polysialic acid synthase, Sialyltransferase 8B, SIAT8-B, Sialyltransferase St8Sia II, ST8SiaII, Sialyltransferase X, STX.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: UL32_GAHVM
Sequence: MANRPTELAAFIRSSGEADGWIEESFKEPYVAFNPDVLMYNDTLFNELLLSAHALKINSIQDVQSDDTVEDAGDIGNEVIHSELVTFIETAADVYALDRQCLVCRVLDMYRRNFGLSALWMADYAFLCSKCLGSPPCATATFIAAFEFVYIMDKHFLSDHGCTLVRSFGKKLLTLEDIQRHFFLHGCFRTDGGVPGRRHDEVITSRSKQGRLVGRRGKFSTAGDAKVLYSNYSYLAQSATRALLMTLSDLGSAPLEVIEGRQKSISGDVRNELRDGIESRKRVAHVIHSVGPVHSCPTTLSVALAGWKDCAKNVECNFFQLESCTLRASSEDNDYEHEWELRASEEKLNVVENVQDMQQIDASQCEHHEHARNEDCTMGYGNLVLLLLAGTGSAPEAASELAFMAAKVRRETVDIFWKNHRREFANDVTAAYSACYGEDSEPDLELGPLMITQLKHAITKGGTSAECLLCNLLLIRTYWLAMRKFKRDIITYSANNIGLFHSIEPVLDAWRSQGHRTDLGDEGCFVTLMKSAGTEAIYKHLFCDPMCAARIAQTNPRSLFDHPDATNHDELALYKARLASQNHFEGRVCAGLWALAYTFKTYQVFPPRPTALSAFVKDAGALLQRHSISLISLEHTLGVYV
What is the function of this protein?
Plays a role in efficient localization of neo-synthesized capsids to nuclear replication compartments, thereby controlling cleavage and packaging of virus genomic DNA.
What are the official names of this protein?
Packaging protein UL32 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL32 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RIBB_SHEPC
Sequence: MNQSLLAPFGTAIERVEAGLNALRQGQGVLVVDDEDRENEGDLIFAAQTLTNTQMAMLIRECSGIVCLCLPDEKVKALELPPMVENNSSQYGTAFTVSIEAKVGVTTGVSAADRVTTIKAAIADGAKPSDLARPGHVYPLRAQPGGVLTRRGHTEGTIDLMQLAGLKPAGVLCEVTNPDGTMARLPEIIAFGAQHNIPVLTIEDIVLYRKSLLANVG
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: TRPA_METVO
Sequence: MKNLENLEKDLKNDLKKDLKKEKPILVSFLVSGDPNIEATLKFMNALDEYCGVIELGIPFSDPIADGSTIQEANVRSLSNGYKIHQSFDVLREFRKFSDTPVVLMTYYNPIYKRGIENFVIQAKEAGANGLIIVDLPLDEAEQYRAICKKHDMGTVFLVAPNTPDERLMYSDEASTLFLYVISTFGITGARGSFEKMTFEFIARAKNLCDKNKLYVGFGISNGEHAEKIIENGADGVIVGSAFVDIIKEYGDSNETIYKLKELARELSEGIHKGYVKYNEKNKY
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ARP10_MOUSE
Sequence: MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKRAGMSKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPILNCWGALPLGGKALHKELETQLLEQCTVDTGAAKGQSLPSVMGSVPEGVLEDIKVRTCFVSDLKRGLQIQAAKFNIDGNNERPTPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLLQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKNFRIHTPPAKANCVAWLGGAVFGALQDILGSRSISKEYYNQTGRIPDWCSLNNPPLEMMFDVGKAQPPLMKRAFSTEK
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
What are the official names of this protein?
Actin-related protein 10, Actin-related protein 11.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: VGR_SOLIN
Sequence: MRFIVLLFICSFIYPCYVSSIGFRRISKVSLKKTKCEDGYFQCNSGECIPVDKKCDYIDHCIDGSDEDFECDHLDEKSFITCAKDQFKCKNQECIPAAKYCDMVNDCLDESDEHDGCVKHLNCTNKFLCTDGHCINKEWVCDGRNDCPDGNDEWNCKANKTSSASSCKTENYQYMCANHRCISLKVVCDKKDDCGDGSDEGPGCTQFNCSSAGCQSNCHQTPKGSVCTCKPGYKLQKDNRTCNDIDECQAYGICDQDCMNVPGSYACTCQREYYLENDKRTCKARAGEATLVFSTRTSILGMHVDSEKFFSLATNLNHAVGVAMYGDYVYWSNLEENGYNTIVKKRTYHPQAPNEVIVTTGLALITGIDVDWITKNIYFADEDNHCIGVCTNDGTYCTVLIKDTDKPTGVALLPTQGKMYWSDWGTFPHIAVAGMDGKNVRIFVNVKLEWPKSVTIDYPNERLYWVDAKSKMIESVRLDGTDRRIVLHDIIQEPFSMTVFQNKLYWSDWESNGIQTCNKFTGKDWKILIRNHNKPYSVHMDHSAIKPNIDNPCYSNPCSQLCMLNQNKGYTCGCTLDKKLNADKHTCQDVKKNQHLLIIQGRKFINYYHEFLGKPKVMTLSLQHMSQQSYNNLVNIISDPLSGQIIICHLQLSTPFLTSTTDILRYDPVHHSSEKIVTINKIFFELAFDYIGNNLYTTNTVNQSIEVINLNTKAMTAFYFKDEVPKYIALAPEESKMFVAFQKSMHSISGLTLYEMQMNGLGKRKLIREGLIGPQLPMYYDRDSKTLFVSDLLPGYIYSHSAQDTRILRSGLKSPHSLTVAGDNLFWIESQNKLYSTNFRTASVKQKTVEFDLSKLNDNMTSLPGHLTPYSRDAQYVVTLRKDDIPKHDCQKNNGNCSHVCLPSLITSFICACPPGMELSNDNRTCISHHECSKNEYKCSEHNICIQRNQLCDGIENCPNGEDETSECRIKGRCKENQFMCKNGDCIRLKDRCNSRYDCTDQSDEQNCEKPKCKSDEFQCKFTETCIPKTKMCDSNPDCDDLSDEEDCRKVECTSNEFKCNNGKCIPNTFVCDNDNDCEDGEDEAAEKCYSKIACKMPKMFKCPNGDCISDSLLCNGINDCNDGSDEVHCLSNVTTHLVNCSLNEYRCLGTDICLPKNVRCDGKNDCPQSDDEQNCTYCFENEFACDNKRCIPELWVCDKANDCGDNSDEKNCDGSKRNFIESNECDEFKCSVGTCLPYSKVCDGNRDCPDGSDETGKCQTACTVNNFCKGMCYKTPAGAVCGCQSGYRLAVDMISCEDINECELDICSQMCRNTIGSYECFCKDEFIIRNDKTSCKAVGPAMEFITVTDNDIRKMTHNLHSTTQLLFPLMGVRVSGLDVNAVSDSVYWSNDEFGTIKKLNIRTNEIVTVKIVEHPQALAVDWITGNVYVNDNSHLNTIKVCNLEKGKCATLVKIQDKMKVASVIVDSINRWLFWAEISLEADHPTSKICRTDMTGADMKIIASDLGFVRGMTIDHVKSKLYWSDDFYKTVESSNFDGSQRKVVLTLNMNHALSISIFEQSLYFLSSDNLLSSCKMYGKRSCEHVNIGANNVFRLFSILHISRQVPFANPCDAEYCDYMCVLKKENATCICSDGESIESNSTCNIKNDLKFVESINFSRNTRNISGIYSITIIVLLVSVLLLCVYYYYQKNKLKSKPASNLSCSSIHFQNPSYDRSDEIEVMLDSMASSELSPGQHEYINPINNKGMKAAENNAKKSNQCSEGKNIEEEKQDALIYFVHNSK
What is the function of this protein?
Involved in uptake of vitellogenin by endocytosis.  Expression is regulated by the juvenile hormone analog, methoprene (in vitro).
What are the official names of this protein?
Vitellogenin receptor, SiVgR.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PEX7_YEAST
Sequence: MLRYHMQGFSGYGVQYSPFFDNRLAVAAGSNFGLVGNGKLFILEIDRSGRIVEVNSFLTQDCLFDLAWNESHENQVLVAQGDGTLRLFDTTFKEFPIAIFKEHEREVFSCNWNLVNRQNFLSSSWDGSIKIWSPLRKQSLMTLTPRPLEITKMVDPLNAIILKKKSFTGISKNRNCVYQAQFSPHDQNLVLSCSGNSYASLFDIRLPSGKNQNNFLVHSGLEALTCDFNKYRPYVVATGGVDNAIRIWDIRMLNKNESATIKRTVPGQLHNSSCINEIPNAHGLAIRKVTWSPHHSNILMSASYDMTCRIWRDLSNDGAKETYKTNSTDATKGSIFNFTQHSEFVFGADWSLWGKPGYVASTAWDGNLFVWNGLG
What is the function of this protein?
Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal, such as 3-oxoacyl-CoA thiolase (PubMed:7957058, PubMed:7535304, PubMed:23812376).  Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol (PubMed:23812376).  Cargo protein-binding triggers interaction with PEX21 and formation of a ternary complex composed of PEX21 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex (PubMed:9094717, PubMed:23812376).
What are the official names of this protein?
Peroxisomal targeting signal 2 receptor, PTS2 receptor, Peroxin-7.
What is the protein family that this protein belongs to?
Belongs to the WD repeat peroxin-7 family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome.
Protein: Y618_ENDTX
Sequence: MIIKVRVIPNSKRNEVVSRVGSILRVKITAPAIEGRANEELCDFLSDFFDVKRSMIFLRKGERGREKTIEVLGRLEEELNEVLDTIP
What are the official names of this protein?
UPF0235 protein TGRD_618.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RNP4_AERPE
Sequence: MKSRRSRCRRSFTTLVRREEERLARWALELARRGLTGEARRVAEQLFQLAASTRVRPPRRVKRLFCKNCRTPLIPGLTARVRLRSQGGMSYTVVTCLSCGWIHRYPYRKGPRGGAPISPPAAEYGSGGRDSGEREDKGPQGPPRQGGRDNRQGGGHQGGPKGD
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_DANRE
Sequence: MMTSFFDQFASPYLLGIPLILVAMLLPWLLFPAPTSRWINNRLITVQTWLTGRFTNQLMTPLNFSGHKWALLFASLMVFLITINLLGLLPYTFTPTTQLSLNMGFAVPLWLATVIIGMKNQPTIALGHLLPEGTPIPLIPALIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAVFVLLPMMPAVAILTASVLFLLTLLEVAVAMIQAYVFILLLSLYLQENI
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GG_EHV1K
Sequence: MLTVLAALSLLSLLTSATGRLAPDELCYAEPRRTGSPPNTQPERPPVIFEPPTIAIKAESKGCELILLDPPIDVSYRREDKVNASIAWFFDFGACRMPIAYREYYGCIGNAVPSPETCDAYSFTLIRTEGIVEFTIVNMSLLFQPGIYDSGNFIYSVLLDYHIFTGRVTLEVEKDTNYPCGMIHGLTAYGNINVDETMDNASPHPRAVGCFPEPIDNEAWGNVTFTELGIPDPNSFLDDEGDYPNISDCHSWESYTYPNTLRQATGPQTLLVGAVGLRILAQAWKFVGDETYDTIRAEAKNLETHVPSSAAESSLENQSTQEESNSPEVAHLRSVNSDDSTHTGGASNGIQDCDSQLKTVYACLALIGLGTCAMIGLIVYICVLRSKLSSLEFWRAQNVKHRNYQRLEYVA
What is the function of this protein?
Chemokine-binding protein that inhibits neutrophils' chemotaxis.
What are the official names of this protein?
Envelope glycoprotein G, gG.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein G family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: F153B_HUMAN
Sequence: MGCAYSCCLEVCCGEDEIVYPRMPGESTVCHREREKPITYHWYHWHPGHIYPRVASMEDYDEDLVQEASSEDVLGVHMVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEILSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHADTGIQTNGDLEDLEEHGPGQTVSEEATEVHMMEGDPDTLAELLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATPAKSDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRKPSKKSRWNVLKCWDIFNIF
What are the official names of this protein?
Protein FAM153B.
What is the protein family that this protein belongs to?
Belongs to the FAM153 family.
Protein: YNB8_YEAST
Sequence: MSTSFQEFKAFCNKVGLDFQWLNLQSSKSVPENGSSEGFSAVSDTVQENIRPATEPLNVNQSKDPVSNFFYDVKNAPLWNVYKRNHSGHSSAEACSGVSSRQAPKNIPEAMVKETVLSNHDNVTIINELLPTSSAMHQEESTAMTTSYLLSHSVNDTCNVMFSSSSHNRAMLPSSLVQRNNATTSPTTDSASENNESVPSLTSSVSTSSSVYSSWNPPHSPHISSFPDGNFASLNAEVTCFDFRRTKDSRTKETNESIIPTEIYCPTNSTDHHKHYPSRKSKQDACAPAPCNQNISCSVVSTAEFSQSNHTLTTVVPSYMQQYLDRPQNWFESKMGKYCPLFLRSTKNIDYDSLEFKFERKMIAVQYLLLDEQSEPRRYYNPSNKSIPFWKRPFNFDTMPSYDQLMEEAECRFYSYQYKYEGFQRIEPYSISCPWKNTQREIDLVLDHIHFSLDVGEKKSLNRKGNITLDTLDSKVDPNIQIKPYQIFPSNNLVYEGLPHPAEQSLILSPDTSLIERAFQALIDICKESIPSSNDCSTRNNNSAPQLTVPEPSKPCRLLLVRESRTATELKTNKKLWLHSQRRNIEVTVPMHPSERGTKSWLRKWLSTFVHQ
What are the official names of this protein?
Uncharacterized protein YNL018C.
What is the protein family that this protein belongs to?
To yeast YNL034w.
Protein: GPX6_ARATH
Sequence: MLRSSIRLLYIRRTSPLLRSLSSSSSSSSSKRFDSAKPLFNSHRIISLPISTTGAKLSRSEHSMAASSEPKSLYDFTVKDAKGNDVDLSIYKGKVLLIVNVASQCGLTNSNYTELAQLYEKYKGHGFEILAFPCNQFGNQEPGTNEEIVQFACTRFKAEYPIFDKVDVNGDKAAPVYKFLKSSKGGLFGDGIKWNFAKFLVDKDGNVVDRFAPTTSPLSIEKDVKKLLGVTA
What is the function of this protein?
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
What are the official names of this protein?
Probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial, AtGPX1, PHGPx.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RELX_HORSE
Sequence: MRRLFLSHVLGAWLLLSQLPRELSGQKPDDVIKACGRELARLRIEICGSLSWKKTVLRLEEPGLEAGQPVEIVSSSISKDAEALNTKLGLNSNLPKEQKATLSERQPSWRELLQQPALKDSNLNLEEFEETILKTQSEVEDDSLSELKNLGLDKHSRKKRMIQLSHKCCYWGCTRKELARQC
What is the function of this protein?
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.
What are the official names of this protein?
Prorelaxin, RXN.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRR30_ARATH
Sequence: MYSSCSLLQRLVWFPFLALVATQLLFIRNVSSLNLTNEYLHHKCLVSEGKYKPGSKYEYILNDYIRFLAAGNFRSGSMHMTSGLKPNAVTILYQCSGDSYNSKCRSCYAAGISGLRRRCPRNKGGIIWFDQCFVEITSISVIDFNISKINYENNFPLHNPNRVSGNIKSFNNETMALLKELALKANNKDNMDNGKMALYASGEKRVGTKKVYAMVQCMRDLVKPKMCKECLESIIKEFPECCDGKQGGRILGTSCDFRYELYPFLRTSDSKTV
What are the official names of this protein?
Cysteine-rich repeat secretory protein 30.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFG_YERPN
Sequence: MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWSGMAKQFEPHHVNIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLRVVGQLKSRLGANPVPLQLAIGAEEKFTGIIDLVKMKAINWNEADQGVTFEYEEIPADMAELAAEWHQNLVESAAEASDELMDKYLGGEELTEEEIKKALRQRVLKSEIILVTCGSAFKNKGVQAMLDAVIEYLPAPTDVESINGILDDGKDTPAVRHSDDKEPFSALAFKIATDPFVGNLTFFRVYSGIVNSGDTVLNSVKSQRERLGRIVQMHANKREEIKEVHAGDIAAAIGLKDVTTGDTLCDPNNPIILERMEFPEPVISVAVEPKTKADQEKMGMALGRLAKEDPSFRVWTDEESGQTIIAGMGELHLDILVDRMRREFNVEANVGKPQVAYRETIRETVKDVEGKHAKQSGGRGQYGHVVIDMSPLPPGGVGYEFVNEIVGGSIPKEFIPAVDKGIQEQLKSGPLAGYPVVDVKVRLHYGSYHDVDSSELAFKLAGSIAFKEGFKRAKPVLLEPIMKVEVETPEDYMGDVMGDLNRRRGIIEGMEDTATGKTVRVKVPLSEMFGYATDLRSQTQGRASYSMEFLEYAEAPSNVAKAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.