PharMolix/UniProtQA huggingface dataset:
Protein: ST_POVKI
Sequence: MDKTLSREEAKQLMQLLCLDMSCWGNLPLMRRQYLVKCKEYHPDKGGNEESMKLLNSLYLKLQDSVSSVHDLNEEEDNIWQSSQVYCKDLCCNKFRLVGAIYGEYYEAYIMKQWDVCIHGYNHECQCIHCILSKYHKEKYKIYRKPPVWIECYCYKCYREWFFFPISMQTFFFWKVIIFNTEIRAVQPLLR
What is the function of this protein?
Promotes efficient viral genome replication by accelerating both G1 and S phase progression of the cell cycle.  Inhibits host PP2A by binding to the A subunit, thereby displacing lower affinity regulatory B subunit.  Inactivation of PP2A in turn results in the transactivation of cyclin A and cyclin D1 promoters.  Late during the infection cycle, ST may induce dephosphorylation of host MTOR, leading to the inhibition of cap-dependent translation.  May establish and maintain high levels of viral genomes during persistent infection in cell culture.
What are the official names of this protein?
Small t antigen, ST, ST-AG.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: HEPA_ASPOR
Sequence: MWWPRATADRLQTCTFWFLWLFTWDDEIDQSTSDLFIHIHKANDFRKESLEYVKFCLGVGDDETAKWDFQNNPPNRPLIRSLDVIGAHLQKVYNHDQIMTFVNEIDYYMGCQQREQKRKLTGRLPIVAEYLETRMGTSAVTSMLALNEYGGALILGLKRR
What is the function of this protein?
Sesquiterpene cyclase; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing.
What are the official names of this protein?
Sesquiterpene cyclase hepA, Heptelidic acid biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: NDK_SHIBS
Sequence: MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DFM1_YEAST
Sequence: MAGPRNVRTLHGNGGRNNDVMGPKEFWLNIPPITRTLFTLAIVMTIVGRLNLINPWYFIYVWNLTFKKVQIWRLLTSCVMLSSRAMPALMELYSIYDRSSQLERGHFGPGLSNRRGPMVTVDYAYYLCFCILAITTATTIIYGSYYPVVLTSGFISCITYTWSIDNANVQIMFYGLIPVWGKYFPLIQLFISFVFNEGDFVISLIGFTTGYLYTCLDTHTLGPIWGMISRKADPTYGISPNGKFSTPWWFTSLYARITGAHNETATFNNNFANVPSSQRETRTFSGRGQRLGTAPATLSQTSGTDSGRASGSQLRSGPSNLNQFQGRGQRVGQTNSPSDSQ
What is the function of this protein?
May be involved in the degradation process of some misfolded endoplasmic reticulum (ER) luminal proteins.  Its precise role is however unclear and its inability to complement der1 mutations, suggests either that it is not involved in degradation process of misfolded proteins, or that it participates in the destruction of specific misfolded ER luminal proteins.
What are the official names of this protein?
DER1-like family member protein 1.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS28_KLULA
Sequence: MDTKTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTTRTIVRNVKGPVREGDILVLMESEREARRLR
What are the official names of this protein?
40S ribosomal protein S28, S33.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: GLGA_ALIF1
Sequence: MVTKTLSIVFVASEVDGLIKSGGLADVAKALPKSLKELGHSVQIVMPAYKTIAGRDDAEIILTTQLEHWPHTAYQVRSLNVDGIPVFAIESGDYFERAEMYAENNQAYADNGERFAFFSAATLDLLPKLLNKKPDIIHVNDWHTGLIPYLLKKRYVENEFYHQTRSVLSIHNAVFKGIFHYDEIACLSEFKSHFVPEASISHTHVSMLKAGVQCADKINAVSPNYAKELLTELGSHGMASDFQDRESDLIGILNGCDYSEWNPEKDSYIPKQFKVNRISMVRGKKACKAALQQELSLPQKDVAMYGMVCRLTNQKGIQYLLPILEQFLKNDLQLVIVGTGDPVLATRLTEIAQEHSDKFAFVEAYDNKLAHWVEAGSDFFIMPSEFEPCGLNQIYSMAYGTLPIVREVGGLKDSVNNYDDDIENATGFSFKNPEPMELLLVLMRSLLLYSQNLNEVKRVQLHAMKQDFCWNKAALKYIEMYRTAINS
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: HMP_ECO57
Sequence: MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFNMSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGEHLLATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAKTPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYRIAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLAMLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQSLPRFTAHTWYRQPSEADRAKGQFDSEGLMDLSKLEGAFSDPTMQFYLCGPVGFMQFAAKQLVDLGVKQENIHYECFGPHKVL
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: SYE1_RHILO
Sequence: MSDKVVTRFAPSPTGYLHIGGARTALFNWLYAKHTGGTMLLRIEDTDRERSTAAATAAILDGLSWLGLGWDGDAVSQFERAPRHREVAEELVRMGKAYYSYETPAELEAMREAARAKGLPPRYNGQWRDRTPSEAPAGVKGAIRIKAPTEGETIVHDRVQGEVRFPNKDLDDFIILRSDGNPTYMHAVVVDDHDMGVTHIIRGDDHLTNAARQTVIYNAMGWDVPSMSHIPLIHGADGAKLSKRHGALGVEAYRAMGYLPEALLNYLARLGWSHGDDEIMSIKDMISWFDIGDVNKGAARFDFAKLEAINGAHMRRMADAQLLDIFIATLPYLEGGPAMAARLNEHNKAQLLAALPGLKERAKTLVELVDGAAFLFATRPLPVDEKAALLLNDGARKILRGAHEALNALSGDWTAAAAEAAVRDYALAGGHKLGAVAQPLRAALTGKSTSPGVFDVLAVLGREESLARIADQID
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YK14_CAEEL
Sequence: MCSVKPKYISLPEQNSLCSLPNSGCCQVEVKIGRSKWEQQKAILVKVDGEPAGKIFIYSQPLIGQMYPLHELKSMGVICEKAGDFLVNLVTERGLKLTFKPIGSTANCFVTALVSGNFTSLTHETHIKTPLQNQEATTSPTIESDLTDKPDTNVYTGSREGYVAPSEKGSNEKKKEVVPNGGDKSVENKKGSDRNVKKTPSKTVTKPLLSESRKRKEAKTLATTQSQDLPAPTKDEPERTNSEPDNGEQEKIKKEKKKGTETSLKDGKNKLNEKIVKPAPTTTPDAGNGGLTPGKEDNKKTVTTSSVEIEVPEKKKAVENAGIIKIS
What are the official names of this protein?
Uncharacterized protein C15H7.4.
Protein: RS4_HERA2
Sequence: MARYTGPVCKLSRREGVDLMLKSGNSGRKVLERRGSQPPGQHGASVRRRQLSDYGVQLREKQKVRRIYGVLERQFRRYYGIATRTTGQTGAVLLQILERRLDNVVFRLGYAVTRAQARQLVNHGHITVNGRKTDIPSALVEVGDVIGVRAESRKRDYFKDLEETKQLNRVSPPSWLSLDAGKMEGVVQTFPSREELDMSINEQLIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CML29_ORYSJ
Sequence: MATPAGGRPSQPQPQAQQLSVDFEALSYISSLVEAFQAFDSDNDGLVTAPELRGLLASLGLDKPEHEVRDMLARADADRDGKLSVEELLDVMNAGQLGLGALGALLQSAVPALESAAGPDGVLGADELARLLSVMGTASVEDCMEIIACMDGDGDGAISVEEFRLMAQLL
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML29, Calmodulin-like protein 29.
Protein: CALM_ACHKL
Sequence: MADQLTEEQIAEFKEAGSLFDKDGDGTITTKELGTVMRSVGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEILEAFQGFDKDGNGFISAAELRHMMTNLGEKLTDEEVDEMIREADIDGDGQINYEEFVKMMMSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: Y2487_GEOSW
Sequence: MEHGDRHITVVDENGNEQLCEILFTFESEDFGKSYVFYYPVGAEFEDEEETEIHVSAFIPGEGEQEGELLPIESEEEWEMIEEVWNTFCAEQDEE
What are the official names of this protein?
UPF0473 protein GWCH70_2487.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: RAPZ_SHISS
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: MIAB_GEOTN
Sequence: MNEKQRLEQTGQIQTASHPADRKSDLERLKAKTTKDYEKYFTSVFLPPNLKEAKKRGKEEVQYVKDFTIPDEFRGMGRGRKFYIRTYGCQMNEHDTEVMAGIFMALGYEPTDRPEDANVILLNTCAIRENAENKVFGELGYLKPLKTTNPDLLLGVCGCMSQEEAVVNKILKQYQYVDLIFGTHNIHRLPYILHEAYMSKEMVVEVWSKEGDVVENLPKVRKGNIKAWVNIMYGCDKFCTYCIVPYTRGKERSRRPEDIIQEVRQLAAQGYKEITLLGQNVNAYGKDFNDIQYGLGDLMDELRKIDIARIRFTTSHPRDFDDRLIEVLAKRGNLVEHIHLPVQSGSTEILKMMGRKYTREEYLELVRKIKAAIPDVALTTDIIVGFPNETDEQFEETLSLYREVEFDSAYTFIYSPREGTPAAKMNDNVPMEVKKERLQRLNALVQEIAAKKMKQYEGQVVEVLVEGESKTNPDVLAGYTRKNKLVHFVGPKSLIGQLVNVRITQAKTWTLTGELANEAIEVN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANTP_DROSU
Sequence: MTMSTNNCESMTSYFTNSYMGADMHHGHYPGNGVTDLDAQQMHHYSQNPNHQGNMPYPRFPPYDRMPYYNGQGMDQQQQQHQGYSRPDSPSSQVGGVMPQAQTNGLPTGGQLVAQQQQQQPQQQSQTPQQQQAQQPQQQQQQLQQLPQVTQQVTHPQQQQQQQQQQQQPVVYASCKLQAAVGVGLGMVPEGGSPPLVDQMTGHHMNAQMSLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYGQQQTGVPPVGAPPQAMMHQGQGPPQMHQGHLPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEGDEITPPNSPQ
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that regulates segmental identity in the mesothorax.  Provides cells with specific positional identities on the anterior-posterior axis (By similarity).
What are the official names of this protein?
Homeotic protein antennapedia.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPDA_NITMU
Sequence: MRIAVMGAGAWGTALALSLCASTASSHQVTLWTRSRQHLADLVSQRINRRYFSAFPLPASLRLTAGLEEAVEDAELALIVVPVSGLRETLREIAASGKKIPVIWGCKGFESQSAKLPHQVAEEEYAGAAPYGVLSGPSFALEIAQGLPAALTLASRDGEFAREVAAQLHAPRLRVYSCTDVVGVETGGAVKNVISIAAGICDGMGFGSNARAALITRGLAEITRLGLKLGGRMETFLGLTGVGDLILTCTGDLSRNRRVGLALAAGRSLPDILQELGHIAEGVHTAREVLRLSHLLGIEMPITKGVCSILDDGVPAGQAVEALLNREPKSEIY
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_ECOSE
Sequence: MVKVYAPASSANMSVGFDVLGAAVIPVDGALLGDVVTVEAAETFGLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYF_ORYSJ
Sequence: MENRNTFSWVKEQMTRSISVSIMIYVITRTSISNAYPIFAQQGYENPREATGRIVCANCHLANKPVDIEVPQAVLPDTVFEAVLRIPYDMQLKQVLANGKKGGLNVGAVLILPEGFELAPPDRISPELKEKIGNLSFQSYRPNKKNILVIGPVPGKKYSEIVFPILSPDPAMKKDVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNATSTGVVRKILRKEKGGYEISIVDASDGRQVIDLIPPGPELLVSEGESIKLDQPLTSNPNVGGFGQGDAEIVLQDPLRVQGLLFFFASVILAQVFLVLKKKQFEKVQLYEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MNMA3_BACFN
Sequence: MKESKKRVLVGMSGGIDSTATCLMLQEQGYEIVGVTMRVWGDEPQDARELAARMGIEHYVADERVPFKDTIVKNFIDEYRQGRTPNPCVMCNPLFKFRMLIEWADKLGCDWIATGHYSRLEERNGHIYIVAGDDDKKDQSYFLWRLGQDVLRRCIFPLGNYTKQTVRDYLREKGYEAKSKEGESMEVCFIKGDYRDFLREQCPELDAEVGPGWFVSSEGVKLGQHKGFPYYTIGQRKGLEIALGKPAYVLKINPQKNTVMLGDAGQLRAEYMVAEQDNIVDEDELFACPDLAVRIRYRSRPIPCRVKRLEDGRLLVRFLAEASAIAPGQSAVFYEGRRVLGGAFIASQRGIGLVIEQNKDWK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 3.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBOH_AMAMK
Sequence: MPPTIRNNFPLFHDFVTASHFITQTILMRLSDAMYLEGSTRFENSHREDKPSTTTLVLLHYPKNFDNAHSGHNKHTDIGSLTLLFTPQWGLQLLSPIQKSKSWLWVQPRPGHAVINVGDSLRFLSGKRLKSCLHRVYPTGEVYQEEDRYSIAYFLRPESAANFEDVDGKVVSAKRWHDEKYVTYTEPHEKQDLSNILTGGMDQILA
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of the psychoactive metabolites ibotenic acid and muscimol (PubMed:32233056).  The first committed step is glutamate hydroxylation by the 2-oxoglutarate-dependent dioxygenase iboH, and the last step is decarboxylation of ibotenic acid to muscimol by the decarboxylase iboD (PubMed:32233056).  The order of the intermediate reactions is somewhat ambiguous (Probable).  IboA likely activates the carboxylic acid at position 5 to introduce an amide bond, and the flavin monooxygenase iboF generates the N-O bond (Probable).  There are several options for the latter step (Probable).  One option is that iboF directly hydroxylates the amide nitrogen formed by iboA to produce a hydroxamic acid species (Probable).  Another option is that iboF hydroxylates an external N-containing compound, whose resulting N-O bond is subsequently introduced into the hydroxyglutamate scaffold (Probable).  The paralogous PLP-dependent cystathionine gamma-synthase-like enzymes iboG1 and iboG2 are likely involved in substitution of the OH group at position 3 by the O-N moiety (Probable).  The first cyclic intermediate is most probably tricholomic acid which is likely desaturated to ibotenic acid by the cytochrome P450 monooxygenase iboC (Probable).
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase iboH, Ibotenic acid biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RL34_ORITB
Sequence: MKRTYQPSKLVRKRRHGFMERMSSVGGRRVLMRRRMKGRRVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ARGB_CLONN
Sequence: MFQLESLKNKIIVIKYGGSIFHTLKNNKSFIEDLKTLKKCGANIIIIHGGGNEISKWLKKLQINNKFINGLRVTDSTTIEIVEMVLSGKINKQLVSTLSKEGINSIGLSGVDNNLLLCKKKYTFVNEIKKDLGYVGEIYKVNTDLLINIMNLGIIPIISPIGTDINGNRYNINADYAASSISSALNANRLIILTDVDGIYKNINDSSSLIENINLTSIKKYIKNGIVNNGMIPKLQCCSHSIEHGTKSVQLINGNRSHCIYNALFNKCGTKIVKGDDLKCQKAI
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAYP2_MACFA
Sequence: MSRNGRDACRELIGFFFTHDQSLTIYEYRQFGKNRTIVLPFIQKSIYSHQCGRRKGKQYRLGDFYVGATLTFLSSDHASLPESIKENTFLKLRITHIDQIALDSLKTASMDQEDDIVIQETNDRLVFKAIQDVLKEKLHKRGVRILTGLGKYFQQLDKEGNGLLDKADFKQALKVFHLEVSEKDFESAWLILDDNGNGKVDYGEFKRGIIGEMNEYRKSYVRKAFMKLDFNKTGSVPITNIRKCYCAKKHSQVISGHSTEEEIKSSFLETLKVACSKSDEVSYGEFEDYYEGLSIEIIDDEDFVTILRTPWGI
What are the official names of this protein?
Calcyphosin-2, Calcyphosine-2.
Protein: ILVD_IGNH4
Sequence: MKRSDVFLRPEYAPHRALWRASGLIDEELRRPLIGVANSWNEIVPGHVHLDKVAEAVKAGIRMAGGTPLEFGTIAVCDGIAMGHEGMRYSLPSREVIADTVEIMVEAHRLDAVVMVTNCDKITPGFLLAAARLEVPVILINGGPMMPGVYGKERIDFKDLMERMNVLIKEGRTEELRKLEESALPGPGSCAGLFTANTMNMLSEAMGLMLPGASTVPAVEARRLWYAKLTGMRIVKMVEEGLTPDKILTRKALENAIAVDMALGGSTNSVLHLEALAYELGIDLPLEVFDEISRKVPHIASISPSGRHFVVDLDRAGGIPAVLKELGEAGLIHKDALTVTGKTVWENVKDAAVLDREVIRPLDNPYSPFGGLAILKGSLAPNGAVVKASAVKRELWKFKGVARVFDREEDAVKAIRGGEIEPGTVIVIRYEGPRGGPGMREMLTATAAVMALGLGDKVALVTDGRFSGATRGPAIGHVSPEAAAGGPIALVQDGDEIVIDIEKRRLDLLVDEKELEERRARWKPKVKPLRRGILRRYAKMALSADKGGALEY
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: TGPA_PSEAE
Sequence: MNAIPRVALVWLLVAQVLVILPHLAYMPLWIAAMWLGCAAWRVQVFRMRAGYPRAWVKLALALLAGAGVWLSRGSLVGLDAGAVLLIAAFILKLVEMKTRRDALVLVFLGFFAVVVGYLFDDGFLAALYSLLPVTALLAALIGLQQSAFASRPWPTLRLAGGLLLQALPLMLLLFLFFPRLGPLWSLPMPGNKGVTGLSESMAPGDIAELGRSAELAFRVRFEGALPPREQLYWRALTMERFDGRRWAQAPQWSGEDALHWQKRGPELRYDVIMQPSSQPWLFALDVAQTDQTDTRLMSDFHLQRRQPVEQRLFYRVSSWPQALRESSIDPRTRWRNLQLPMHGNPRARALADELRQAHAQPQALVAALLQRFNHEPFAYTLKPPATGADGVDDFLFDTRSGFCAHYAGAMAFVLRAAGIPARVVAGYQGGELNPAGNYLLVHQFDAHAWVEYWQPEQGWLSVDPTYQVAPERIEQGLEQALAGDSEYLADAPLSPLRYRGLPWLNDMRLAWDSLNYGWQRWVLAYQGEQQGAFLQRWFGGLDPTRLGLLLGAAAILSVGLLALFLLKPWQGRGDLRSRQLRRFERLLEMHGLRRSPGEGLRSYGERAARVLPAQAPAIAAFVGAFEAQRYGHGGADDPGLRLRALRRALPWRLVRTPTRDGRGEEQA
What is the function of this protein?
Displays transglutaminase activity (TGase) in vitro.  Plays a critical role in the viability of P. aeruginosa.  Might contribute to an essential function linked to the cell wall.
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase, Transglutaminase protein A, TGase A.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase-like superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GTR3_CANLF
Sequence: MGTQKVTVSLIFALSIATIGSFQFGYNTGVINAPETIIKDFLNYTLEEKSENLPTEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMVNLLAVAGGCLMGFCKIAQSVEMLILGRLIIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLKVIMGTEELWPLLLGFTIIPAVLQSAALPFCPESPRFLLINRKEEENAKEILQRLWGTQDVSQDIQEMKDESARMAQEKQVTVLELFRSRSYRQPIIISIMLQLSQQLSGINAVFYYSTGIFKDAGVEEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSILMTISLLLKDNYNWMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAFYLGAYVFIIFTGFLIVFLVFTFFKVPETRGRTFEEITRAFEGQGQDANRAEKGPIVEMNSMQPVKETATV
What is the function of this protein?
Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane.  Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate.  Does not mediate fructose transport.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 3, Glucose transporter type 3, brain, GLUT-3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Localized to densely spaced patches along neuronal processes.
Protein: CH10_SALG2
Sequence: MSIRPLHDRVIVKRKEVESKSAGGIVLTGSAAGKSTRGEIIAVGKGRILDNGTVQPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_SHIB3
Sequence: MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_PSEPK
Sequence: MSRVCQVTGKGPVTGNNISHANNKTRRRFLPNLQHHRFWVESEKRFVRLRVSAKGMRIIDKRGIDAVLVDIRKAGAKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.