PharMolix/UniProtQA huggingface dataset:
Protein: Y2246_YERPA
Sequence: MQWLADYWWIILILLVGMILNGIKELRRLDHKRFLDNKPELPPHRDNNAQWDDEDDWPDQNKKK
What are the official names of this protein?
UPF0370 protein YPA_2246.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: UPP_CLAM3
Sequence: MRVHVADHPLITHKLTALRDRTTPSPVFRSLADELVTLLAYEATRDVRVETITVQTPVAPAEGLTLSDPKPLVVPILRAGLGMLDGLMRLMPSAEVGFLGMVRNEETLQPDIYAERLPTDLSNRQCFVVDPMLATGGSLIAAIEYLFDRGAVDVTCICLIAAPEGLKAVEEATAGREVTIVLGALDERLDEVGYIIPGLGDAGDRLYGTAAH
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: GAL1_LIMRJ
Sequence: MDKQQFLAEYQDVFKEPGKDVFFSPGRINVIGEHTDYNGGHVFPCAISIGTYGVYGPREDTTVAIYSANSAKEEDSKIITFDINDTEPQNAKDEKWVNYFKGMLVYLKQRGFKIDHGFNLYIHGFLPYGSGLSSSASIEMLMGNILKDEFNLDIDEIELVKLGQKTENDFVGLNSGIMDQFAVGMGKENNAIYLDCNTLEYKYLPLELGDYEIIIMSTNKNHSLAGSKYNERVQECEEAVKRLNKKLDINKLGELDSDTFDQYTYLIDDDTLIRRARHAVSENERTKKAIDAMEKGDLEELGRLINASHVSLKYDYEVTGKELDTLAENAWNQPGCLGARMVGGGFAGSAIAIVKKSEAENFKKNVGKIYRDKIGYDASFYDAEVVDGPHKL
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_OCEIH
Sequence: MSEQKRTPIFTEYASHGAKTIDFGGWDLPVQFSSIKHEHEVTRTKAGLFDVSHMGEISVKGPKSESFLQYVLTNDISKLEPGKAQYTIMCYEDGGTVDDLIVYKLDDEDYLLVVNAANTEKDANWIKQKNTYSNDEIVIEDVSNQYVQLAIQGPKAVEILQKCTDENVQEIKFFRFKNNVALKGIEAKALISRTGYTGEDGFEIYIDASSGVALWKLLLEKGEANGLEPIGLGARDTLRFEANLALYGQELSKDISPIEAGLGFAVKVNKGPDFIGKEVLKNQVENGTDRKLVGIEMIDKGIPRHEYEVLKDNKEIGFITSGTQSPTLNKNVGLALINISYTEIGTEVDVKVRKRILKAKIVPTPFYKRGR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: TRPC_BRUSU
Sequence: MSTDILRKIEAYKREEIAAAKARLALDELKARTRDQSAPRGFLKALEAKRAAGQFALIAEIKKASPSKGLIRPDFDPPALAKAYEEGGAACLSVLTDTPSFQGAPEFLTAARQACSLPALRKDFLFDPYQVYEARSWGADCILIIMASVDDDLAKELEDTAFALGMDALIEVHDEAEMERALKLSSRLLGVNNRNLRSFEVNLAVSERLAKMAPSDRLLVGESGIFTHEDCLRLEKSGIGTFLIGESLMRQHDVAAATRALLTGAEKL
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RL18_SHEPA
Sequence: MDKKTSRLRRALRARKKIQELGVNRLVVHRTPRHTYAQVISPENVVLAAASTAEKAVTEQLKYTGNVDAAKVVGKTVAERAIEKGVAVVAFDRSGFKYHGRVAALADAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: STIMA_HUMAN
Sequence: MQGPAGNASRGLPGGPPSTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTPLKPVKKKKHRFGLPV
What is the function of this protein?
Acts as a regulator of store-operated Ca(2+) entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679, PubMed:26644574).  SOCE is a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:26322679).  Acts by interacting with STIM1, promoting STIM1 conformational switch (PubMed:26322679).  Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574).  Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574).
What are the official names of this protein?
Store-operated calcium entry regulator STIMATE, STIM-activating enhancer encoded by TMEM110, Transmembrane protein 110.
What is the protein family that this protein belongs to?
Belongs to the STIMATE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with STIM1 at ER-plasma membrane (ER-PM) junctions, also called cortical endoplasmic reticulum (ER), in store-depleted calcium cells (PubMed:26644574). May translocate to ER-PM junctions in a STIM1-dependent manner in store- depleted cells (Probable).
Protein: BIOD_BACCR
Sequence: MSGFFITATDTEVGKTVVAGAIAGVFRELGYNVGVYKPLQSGHVASNPEGDAARLKSLSGVPTQENEICPYSIEEPLAPRLAMKRAGRVVKLKEITDYYNGLLKEFNSLFVEGAGGLAVPYTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAKAHGLTVAGVILSGCKECEMERVQENKEMIEELSGVPVLGLLPFFAGEFTKEEVLESAKEHIMISKLEEFIQNESNVAGAPSM
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATA2_SOLTU
Sequence: MDPSKYRPSSAYDTPFLTTNAGGPVYNNVSSLTVGPRGPVLLEDYYLIEKLATFDREKIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGAQTPVICRFSTVVHERGSPESIRDIRGFAVKFYTREGNFDLVGNNVPVFFNRDAKSFPDTIRALKPNPKSHIQENWRILDFFSFLPESLHTFAFFYDDVCLPTDYRHMEGFGVHAYQLINKEGKAHYVKFHWKPTCGVKSMSEEEAIRVGGTNHSHATKDLYDSIAAGNYPEWKLFIQTMDPEDVDKFDFDPLDVTKTWPEDLLPLIPVGRLVLNRNIDNFFAENEQLAFNPGHIVPGIYYSEDKLLQTRIFAYADTQRHRIGPNYMQLPVNAPKCGHHNNHRDGAMNMTHRDEEVDYLPSRFDPCRPAEQYPIPACVLNGRRTNCVIPKENNFKQAGERYRSWESDRQDRYITKWVESLSDPRVTHEIRSIWISYLSQADKSCGQKVASRLTVKPTM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 2.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: TALAA_DROME
Sequence: MLDPTGTYRRPRDTQDSRQKRRQDCLDPTGQY
What is the function of this protein?
One of four peptides (tal-1A, tal-2A, tal-3A and tal-AA) produced from a polycistronic gene that function redundantly in several developmental processes (PubMed:17439302, PubMed:17486114, PubMed:25344753, PubMed:21527259).  Required in early stages of leg development for the intercalation of the tarsal segments during the mid-third instar stage and later for tarsal joint formation (PubMed:17439302, PubMed:18801356, PubMed:21527259).  Promotes the post-translational modification of ovo isoform B (svb) into its active form which in turn initiates trichome development and promotes tarsal joint development (PubMed:21527259, PubMed:20647469, PubMed:26383956).  This is likely due to recruitment of the E3 ubiquitin-protein ligase Ubr3 to svb for ubiquitination of its N-terminus, converting svb into a transcriptional activator (PubMed:26383956).  Also enhances interaction of Ubr3 with Diap1 (PubMed:26383956).  Required for correct wing and leg formation through its regulation of several genes including those in the Notch signaling pathway (PubMed:18801356, PubMed:21527259, PubMed:21682860).  Essential for denticle formation and may have a role in the developmental timing of trichome differentiation (PubMed:17486114, PubMed:25344753).  Essential for the development of taenidial folds in the trachea (PubMed:17486114).
What are the official names of this protein?
Peptide tarsal-less AA, Peptide polished rice 4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TIM50_BOVIN
Sequence: MAASAAVFLRLRSGLRQGARGLCARLATPPPRAPDQAAEIGSRAGTKAQTQGPQQQRSSEGPSYAKKVALWLARLLGAGGTVSVIYIFGNNAVDENGAKIPDEFDNDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLREPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEEDPLEAFKQRQSRLEQEEQQRLAELSKSSKQNLFFSSLTSRLWPRSKQP
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Has some phosphatase activity in vitro; however such activity may not be relevant in vivo.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM50.
What is the protein family that this protein belongs to?
Belongs to the TIM50 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DTNB_MOUSE
Sequence: MIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHLVPPRPLTNMNDTVVSHMSSGVPTPTKRLQYSQDMPNLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSGAEAEEQAGTEKTREGLPPRGTFLSVFLLHTWTKLAGCQTHSTSRERSQAYGKWGGTA
What is the function of this protein?
Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids (PubMed:11585924).  May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation (PubMed:20530487).  May be required for proper maturation and function of a subset of inhibitory synapses (PubMed:16540561).
What are the official names of this protein?
Dystrobrevin beta, DTN-B, mDTN-BDTN-B, Beta-dystrobrevin.
What is the protein family that this protein belongs to?
Belongs to the dystrophin family. Dystrobrevin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Postsynaptic density. Cell projection, dendrite. Basal cell membrane. Postsynapse. Nucleus. Note=Localized at inhibitory synapses on the dendrites of cerebellar Purkinje cells.
Protein: Y1107_HAEIN
Sequence: MKTTHRTRMPTTLEAFSPIIVMLLLLGLGYALFDLPAEPLMIISTVFAGFLVFKLGHCYLDILDAISEKIAKTMPALLILITVGLLIGTWISGGTIPMMIYYGLKAISPEYLYVTALFLTAIVSICTGTSWGSAGTVGVAFMGVAIGLDANLAATAGAVVAGAYFGDKLSPLSDTTNIASAAAGVDLYEHIAHLLYTTLPSFILSATVYVVYGLNYDFSNVATPEKVNTMIHELEQVYHFNFLLLIPVAIVLWGSITKKPTIPVMLLSAFIAIINAILIQKFSLSDVINSAVNGFDTSMIHHTSVSSDLSRLLNRGGMNSMMGTLLICFCALSFAGVLQLSGALTVIIQKLLTFVHSTLSLIITTILCGLTMIGVTCNGQISILIPGEMLKNAYVEKGLHPKNLSRTAEDSATIIEPILPWTAAGAYMAGTLGVATLSYLPWAILCWSGIIFAIIYGASGIGIAKLKK
What are the official names of this protein?
Uncharacterized Na(+)/H(+) antiporter HI_1107.
What is the protein family that this protein belongs to?
Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAA_MYCPA
Sequence: MPRLSEPSPYVEFDRKQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFVIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELDRRNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHLKYDIIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFGIYVDARIEDIEQWYISRFLAMRSTAFADPESHFHHYAALNDTKAVAAAREIWRSINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_COXBU
Sequence: MKPNDKVIIGRLARPYGLRGWIKVVSFTHPIDNLLNHPTWQIQHNNEWQPLKLQAGKLHEPFLVVKLENIDDPETAKHYTNDLIAIERGALGALKEGDYYWTDLIGLAVVNTHGIELGTVDSLIETGSNDVLVVRSKERERLIPYTSYTIQSIDLEKKIIVVEWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_STAHJ
Sequence: MQVEVGQIVNTHGIKGEVKVKSNSDFTDTRFQPGEVLTVNHQNHEEQLTVLSYRVHKGFHMLKFEGINNINDVEQYKGDYLYQERDHEDIELAENEYYYSDIIGSTVFDNDNQPIGRVINIFETGANDVWVVKGEKEYLIPYIADVVKEIDIENKTIRITPMEGLLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_CAMC1
Sequence: MRHKHGYRKLGRTSSHRSALLKNLAIAIIKSEKIETTLPKAKELRSYVEKLITRARKGDSNAHRAVFASLQDKETTNKLVTEVAPKFKERNGGYTRIIKTRVRRGDAAEMAYIELVAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: AATF_CHICK
Sequence: MAAPLAQQLEELLNPRPDLRDPEDDAEEATVAKVIDRFEDETADDVLPVGNIRKKASVSLLEADQRYSGKATSRKALQEELWGDALSEEGSAEEALDEWYSGSEDSEDNGSSGSKTEEQPSSAGSDQEDNLEDDEERDSSAKAPKFSFQNITDFEKFAEGMDDVGSSDGEDEDDASMEEGSDDEKYEGENHDHVKDTNDNEDDGGVMTFSKGQTSDEVEKGKAVKNQLALWDQILEGRIKMQKALVIVNRLPQPDTFPLFRKEGGQEFDSAVESCCKAVDTLLRVLVDIQDELLYQCPGTRHLVDGKQSKPESDDEIPSSSDEERAGEAQEKRKRPPKRKLKAEDIPEFIAKRYSDYRTYRNHILQKWHEKTKLASGKMAKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKEEQDSHPVPEHLPENSEVLPQADSNRHLKDIDEEIFDDDDFYHQLLRELIERKTTSLDPNDQVAMGRQWLAIQKLRSKIKKKVDRKASKGRKIRYHVHSKLVSFMAPIDHCTMNDDARTELYRSLFGRMMQSEGPERGWHPGPPAPAGSAPYTL
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  May function as a general inhibitor of the histone deacetylase HDAC1 (By similarity).
What are the official names of this protein?
Protein AATF, Apoptosis-antagonizing transcription factor.
What is the protein family that this protein belongs to?
Belongs to the AATF family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CLPX_STRP7
Sequence: MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVDGTDKPILETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: FLGH_ECOHS
Sequence: MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: TRM13_MOUSE
Sequence: MEAPAATSPSIGFPIDGRCNYFVEKKKRFCRMVAAAGKRFCGEHAGSAEEENTRKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFFIQDINAGLKDETEIPEQLVPFSSLSEEQLENLIKKLRKASEGLNSTHEDHIMSHPALHDALNDPRNGDCAVKHLKQQASILGNIEKLKLLGPRRCFVEFGAGKGKLSHWVDIALKDAENVHFILVERVTTRFKVDGKHRKKDSVFERLQIDIQHLCLNRVPVLREGRLPVVGIGKHLCGVATDVALRCLVETYAASFEEKDEEPLAKRIKNDKTEKESNTLAKEGSEKDVPETWTPVAGIVIALCCHHRCDWRHYVGKEYFKALGLGAVEFYYFQRMSSWATCGMRTSLEGSDVTPERKDAQRDENEEHDDGGDRLTDGNTDSLPGILTVEEKKKIGHLCKLLIDQGRLQYLQQKGFSPALQYYTDPLVSLENVLLTAVPAHPSSQEKHHQ
What is the function of this protein?
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
What are the official names of this protein?
tRNA:m(4)X modification enzyme TRM13 homolog, Coiled-coil domain-containing protein 76.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase TRM13 family.
Protein: DER_CLOB8
Sequence: MGKPIVAIVGRPNVGKSTLFNKLAGKRISIVQDTPGVTRDRVYAEAEWLRYNFTMIDTGGIEPENNDIIIKQMRRQANIAIETADVIIFIVDGKEGLTAADNEVATMLRKSKKPVVLVVNKVDNLKDENNAYEFYNLGIGDPMAISAGQGLGLGDMLDEVVKHFDKSIYDEEDDEYIRIAMIGKPNVGKSSLINKLLGEERVIVSDIPGTTRDSIDSHLETEEGKFILVDTAGLRRKSKVKEEIERYSVIRTYAAIERADVCILMIDATEGITEQDEKIIGYAHELRKAIMVIVNKWDLVEKDDKTLDKFKKDLQSNLKFLSYAEYLFISALTGQRTNKVLKLARYCYDNYNKRISTGILNDVISKAVLMKEPPIVGIKRMKIYYATQVATKPPKFVFFINDESARHFSYERYLENQLRDSFDFKGTGIQIEYRQRKE
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PROA_CHRVO
Sequence: MNVKEYMQQLGQAARKASRLLARADTNQKNAALHAIADAIVREQEALLAANRQDLDAARQAGLDDAMLDRLTLSAKGVLAMADGLRQIAALPDPVGEIDDMCYRPSGIQLGKMRVPLGVVGIIYEARPNVTADAAGLCLKSGNATILRGGSEAFHSNQAIAACVHEGLAAAGLPAEAVQVLATTDRAAVGELIAMPEYVDVIVPRGGKGLIARISAEARVPVIKHLDGNCHVYIDDTANPDKAFNIALNAKTHRYGTCNTMETLLVHTAFAEFMLPRLAEAYWEKGVELRGCERVRAILGEPVKAATDEDWATEYLAPVLAVKVVKDIDEAIEHINRWGSHHTDAIVTEDYGRSRRFLREVDSASVMVNASTRFADGFEYGLGAEIGISTDKIHARGPVGLNGLTSQKWIVLGDGQVRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRPE_BACC0
Sequence: MKYDIIGDIHGCLQEFQNLTEKLGYNWSSGLPVHPDQRKLAFVGDITDRGPHSLRMIEIVWELVIHKKVAYYAPGNHCNKLYRFFLGRNVTVAHGLETTVAEYEALPSHKQNMIKEKFITLYEQSPLYHVLDEKRLLVCHAGIRQDYIGRQDKKVQTFVLYGDITGEKHADGSPVRRDWAKEYKGTTWIVYGHTPVKEPRFVNHTVNIDTGAVFGGRLTALRYPEMETVSVPSSLPFVPEKFRPIS
What is the function of this protein?
Asymmetrically hydrolyzes Ap4p to yield AMP and ATP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical], Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the PrpE family.
Protein: ISPDF_BARHE
Sequence: MSIAAVILAAGRGKRAGSLPKKPKQYRLLGQEPVICHTVRCFCQNPAITTIILVIHPEDRQICEQAIADFKEQLIIVEGGNTRQKSTLRGLQALRKFKPKYVHIHDGARPFVENKLLEQIHTTVTPQEGVLPVLAVCDTLKRINSTHHVLETIPRTHLYSAQTPQCFPFERILAAHEKAIKTCKKEFTDDSAIAEWFGISMRTIPGSPHNIKITWHEDLNTAHLYLQKKMQMFPDIRTGNGYDVHSFEEGNSLILCGIKIPFHKKLNGHSDADVALHALTDALLATRGAGDIGTHFPPSDPQWQNVSSEIFLRHALDIVKQAGGRIANVDITLIAEEPKIGPYRHAMVGNLMNMLTILPDRISIKATTNEKLGFIGRGEGIAAFATANVLYPGEIPK
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: GCST_GEOKA
Sequence: MLKRTPLFSVYARCGAKTIEFGGWEMPVQFSSIKEEHEAVRTRAGLFDVSHMGEIVVRGRGSLAFLQKLMTNDVAKLRPGRAQYTLMCYEDGGTVDDLLIYQKGENDYLLVVNAANTEKDFAWLSGHVEGDVELQDVSSETAQLALQGPAAERVLQRLTDFDLAALRPFSFADGVEVSGVKALVSRTGYTGEDGFELYCKAEDAAALWEAILAAGARDSVLPCGLGARDTLRFEACLPLYGQELSDSISPVEAGLGFAVKTEKETPFIGQAVLKRQKEEGPPRRLVGIEMIDRGIPRHGYLVFADGEEVGFVTTGTQSPTLKKNIGLALVKADVAAIGREVEVDIRGKRLKANIVPIPFYRRAK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: MHPB_MYCVP
Sequence: MAKSQMALCCMSHSPLLNLPGPAQELLDDIEGAIAAAREFVAAFDPDLVVTFSPDHYNGFFYRAMPPFCVGTAAAGVGDYGTYQGPLDVPADLAIDCARAVLDSDVDVAVSAAMDVDHGTVQPLQKLFGDATAKPVIPVFVNSVATPLGPMRRVRALGAAVGTHLAGLGKRVLVIGSGGLSHDPPVPTLATAPPAALDRIVRGVPMTTEQRQARQAAVIEAAREFASGQGALAPLNPDWDRAFLDLLDNGRLAEVDSWDNRWIAEQAGNSAHEVRTWVAAFAALAAQGKYETGNRYYRAAPELIAGFAIRTAVCTS
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase, 3-carboxyethylcatechol 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: LEUC_EDWI9
Sequence: MGKTLYQKLYDAHIVHQTPGETPLLYIDRHLVHEVTSPQAFDGLRAQRRRVRRPEHTFATMDHNVSTQSRDIHACGEMARVQMETLMANCREFGVQLYDLHHPHQGIVHVIGPEQGMTLPGSTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQDRARTMQVVIQGRCAEGISAKDIVLAVIGHLGHAGGTGYVVEFCGPAVEALSMEGRMTLCNMAIELGAKAGLIAPDETTFAYLQGRPFAPQGAQWQQAVDHWRTLRSDADARYDRTVTLQADDIAPQVTWGTNPGQVIAIDTPIPSPASLSDPIARASAHKALAYMDLQPGTRMSDVAIDRVFIGSCTNSRIEDLRAAAAVARGRRVAPGVQAMVVPGSGPVKAQAEAEGLDKIFTEAGFEWRLPGCSMCLAMNNDRLGSGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVCGHFADIRQFQEPAHD
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.