PharMolix/UniProtQA huggingface dataset:
Protein: RAPA_SALTI
Sequence: MPFTLGQRWISDTESELGLGTVVAMDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHEGWQLHIDEVKEENGLLVYVGTRLDTEETNVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPYSGLRGQRTNLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYTEAQHDAYNPFETEQLVICSLDFARRNKQRLEHLCDAEWDLLVVDEAHHLVWSTDAPSREYMAIEQLAERVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQKNYRPVADAVAMLLAGNKLSNDELNRLGDLIGEQDIEPLLQAANSDRDDAQAARDELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTVKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKATTALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRAIYDSAYASLINYLAAPEETDGFDDLIKSCREQHEALKAQLEQGRDRLLEINSNGGEKAQQLAQSIEEQDDDTNLIAFAMNLFDIVGINQDDRGDNLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELVYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLSAVNRHTGSKLVNAVQQDVHAILQLGETQIEQSARALIDNARREADEKLSGELSRLEALRAVNPNIRDDELAAIDSNRQQVLESLNQAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: HIS4_BACC7
Sequence: MEIFPAIDLKEGRCVRLYQGEFSKETVMNEDPVAQAIIFETFGAKRLHIVDLDGAVAGESLNLSVIERICKAVRIPVQVGGGIRSLVSVEKLFSVGVDKVILGTAALYDKPFLEETVRLYKEKIIVGIDAKNGFVATRGWLDVSEISYIDLAKQMEKIGVQTIVFTDISKDGTLAGPNVEQLELLQKNVATRLIASGGIASIQDVKKLNDMNIYGVIIGKALYEKTIDLEEVLEVTKLC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHIT_RICPR
Sequence: MYNKENVFAKIITKNLPAEIIYEDKQILAFKDIAPIAPVHIIVIPKNEYIDYTDFISKASIDEIKHFFSKIADIANEAGLDKVGYRLITNKGEKSGQTIFHFHFHIIGGKKLIGLINNND
What are the official names of this protein?
Uncharacterized HIT-like protein RP317.
Protein: PDZD9_MOUSE
Sequence: MEKGSLKSKNEKEQLSKAKASVSSLNKVIQTKLTVGNLGLGLVVIQNGPYLQISHLINKGAAASDGILQPGDVLISVGHANVLGYTLREFLKLLQNITIGTVLQIKAYRGFLEIPQEWQDVYDLIPETKFPIPHTPKKTEPARESLVKDDHEEAVLDKKLKYYRYPRSVWNHPVRTPISISTEWHGYEKKERTISVGRDINSDVVIHKDDKKELRAPSPYWAMVEQDRAISSSSSSTANSSSSDAFWLEDYAQVEEGNGKQVSKFG
What are the official names of this protein?
PDZ domain-containing protein 9.
Protein: TRPA1_MOUSE
Sequence: MKRGLRRILLPEERKEVQGVVYRGVGEDMDCSKESFKVDIEGDMCRLEDFIKNRRKLSKYEDENLCPLHHAAAEGQVELMELIINGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFLLSQGANPNLRNRNMMSPLHIAVHGMYNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKKCMELILAYGEKNGYSRETHINFVNHKKASPLHLAVQSGDLDMIKMCLDNGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVDGNQETLLHRASLFDHHDLAEYLISVGADINSTDSEGRSPLILATASASWNIVNLLLCKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFMQMQHIKELVMDEDNDGCTPLHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTIRNKRWDECLQVFTHNSPSNRCPIMEMVEYLPECMKVLLDFCMIPSTEDKSCQDYHIEYNFKYLQCPLSMTKKVAPTQDVVYEPLTILNVMVQHNRIELLNHPVCREYLLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTGIINGTSSTHEERIDTLNSFPIKICMILVFLSSIFGYCKEVIQIFQQKRNYFLDYNNALEWVIYTTSIIFVLPLFLNIPAYMQWQCGAIAIFFYWMNFLLYLQRFENCGIFIVMLEVIFKTLLRSTGVFIFLLLAFGLSFYVLLNFQDAFSTPLLSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQRSTIVYPNRPRHGRMLRFFHYFLNMQETRQEVPNIDTCLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISETEDEDNHCSFQDRFKKERLEQMHSKWNFVLNAVKTKTHCSISHPDF
What is the function of this protein?
Receptor-activated non-selective cation channel involved in pain detection and possibly also in cold perception, oxygen concentration perception, cough, itch, and inner ear function (PubMed:24140646).  Shows 8-fold preference for divalent over monovalent cations.  Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of irritants, such as allylthiocyanate (AITC) found in mustard oil or wasabi, cinnamaldehyde, diallyl disulfide (DADS) from garlic, and acrolein, an irritant from tears gas and vehicle exhaust fumes (PubMed:16564016).  Acts also as an ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana.  Is activated by a large variety of structurally unrelated electrophilic and non-electrophilic chemical compounds.  Electrophilic ligands activate TRPA1 by interacting with critical N-terminal Cys residues in a covalent manner, whereas mechanisms of non-electrophilic ligands are not well determined.  May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds.  Probably operated by a phosphatidylinositol second messenger system.
What are the official names of this protein?
Transient receptor potential cation channel subfamily A member 1, Ankyrin-like with transmembrane domains protein 1, Wasabi receptor.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPB_LISIN
Sequence: MTYQAPDENGFYGKFGGRFVPETLMKAVKELDEAYRASKTDAAFQKELNYYLKEYVGRETPLYFAEQLTAYAGGAKIYLKREDLNHTGAHKINNTIGQALLARQMGKQKVVAETGAGQHGVATATVAALFNMECTIFMGEEDVKRQSLNVFRMELLGAKVVSVKAGSRTLKDAVNEALRFWVANVEDTHYIMGSVLGPHPFPEIVRDYQSVIGTEARKQHLEKEGKLPEAIVACVGGGSNAMGLFYPFVDDSSVQMHGVEAAGHGLETEFHAATISKGEIGILHGAMMDVLQDENGQILEAFSISAGLDYPGIGPEHSFFRDLGRAEYHSVTDDEAVEAFQLLCRTEGIIPALESSHAISYAVKLASQMRPDESMVVCLSGRGDKDVNQLKERLEGQTND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: Y602_METJA
Sequence: MLLEKSKIEIIEQFIHILEILEMYAKEGSDEKAIIRLMLDYLEKGYVLDDDILPIASKISEIAKKVGSFDMKREISLLLFGERKRLTKSQKNKIKKIIEILEYLKSYIEKKPYKSYEDKLILNLIGLKILRLDNGIVLDYNSEVRSLTNMALRVGSYELKNEIELLLTGRRRRKLTEEFIQKRLSIIKILEMVKDFIDKKEFKSSFDYEALFLINLKIYRIEEGILKNFDEEIESILNIARKVGNHKLREQIVLLKESIKN
What are the official names of this protein?
Uncharacterized protein MJ0602.
Protein: STX6_SCOAN
Sequence: EITVEPVRHPKKDPSEAE
What are the official names of this protein?
Scolopendra 5971.33 Da toxin.
What is the protein family that this protein belongs to?
Belongs to the scolopendra toxin 6 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GAT1_YEAST
Sequence: MHVFFPLLFRPSPVLFIACAYIYIDIYIHCTRCTVVNITMSTNRVPNLDPDLNLNKEIWDLYSSAQKILPDSNRILNLSWRLHNRTSFHRINRIMQHSNSIMDFSASPFASGVNAAGPGNNDLDDTDTDNQQFFLSDMNLNGSSVFENVFDDDDDDDDVETHSIVHSDLLNDMDSASQRASHNASGFPNFLDTSCSSSFDDHFIFTNNLPFLNNNSINNNHSHNSSHNNNSPSIANNTNANTNTNTSASTNTNSPLLRRNPSPSIVKPGSRRNSSVRKKKPALKKIKSSTSVQSSATPPSNTSSNPDIKCSNCTTSTTPLWRKDPKGLPLCNACGLFLKLHGVTRPLSLKTDIIKKRQRSSTKINNNITPPPSSSLNPGAAGKKKNYTASVAASKRKNSLNIVAPLKSQDIPIPKIASPSIPQYLRSNTRHHLSSSVPIEAETFSSFRPDMNMTMNMNLHNASTSSFNNEAFWKPLDSAIDHHSGDTNPNSNMNTTPNGNLSLDWLNLNL
What is the function of this protein?
Positive regulator of multiple nitrogen catabolic genes.
What are the official names of this protein?
Transcriptional regulatory protein GAT1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYH_ACAM1
Sequence: MGFIQVSRGTRDILPDEVIYWQYVEATARQLLHQAAYRELRTPIFEQTNLFERGIGEATDVVGKEMYTFQDRGDRSITLRPEGTAGAVRSFIENKLHAQGGVQRLWYIGPMFRYERPGAGRQRQFHQIGVEALGSQDPRADAEVIAIASQLLKSLGVPDWTLSLNSLGTAEDRQKYREALVTYLSQYKDDLDPDSQDRLQRNPLRILDSKDPKTKEIAQSAPNILDYLGTDSKQHFDRVQQLLTDLDIAYKLNPCLVRGLDYYTHTAFEFELEGLGNQATVCGGGRYDRLVSELGGPETPAVGWAIGMERLILLLQNAEITLNQSLDFYCVARGPEAEAQALLICQNLRENGFSVEMDLSGSAFGKQLKRANRSGALACLILGDTEACDRTVQLKWLASGEQESIAQADLRNLTSQLQSKLTAAKGNSST
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD177_HUMAN
Sequence: MSAVLLLALLGFILPLPGVQALLCQFGTVQHVWKVSDLPRQWTPKNTSCDSGLGCQDTLMLIESGPQVSLVLSKGCTEAKDQEPRVTEHRMGPGLSLISYTFVCRQEDFCNNLVNSLPLWAPQPPADPGSLRCPVCLSMEGCLEGTTEEICPKGTTHCYDGLLRLRGGGIFSNLRVQGCMPQPGCNLLNGTQEIGPVGMTENCNRKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMCEVGQVCQETLLLLDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDLCNSASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHLSGGGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSAREKRDVQPPASQHEGGGAEGLESLTWGVGLALAPALWWGVVCPSC
What is the function of this protein?
In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (PubMed:21193407).  In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (PubMed:28807980).  Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (PubMed:17580308).  However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo (PubMed:23461681).  Acts as a receptor for the mature form of protease PRTN3 allowing its display at the cell surface of neutrophils (PubMed:17244676, PubMed:18462208).  By displaying PRTN3 at the neutrophil cell surface, may play a role in enhancing endothelial cell junctional integrity and thus vascular integrity during neutrophil diapedesis (PubMed:23202369).
What are the official names of this protein?
CD177 antigen, Human neutrophil alloantigen 2a, HNA-2a, NB1 glycoprotein, NB1 GP, Polycythemia rubra vera protein 1, PRV-1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft; Lipid-anchor, GPI-like-anchor. Secreted. Cytoplasmic granule membrane. Cell projection, lamellipodium. Note=Cell surface expression on neutrophils is increased upon TNF-alpha, fMLP or CXCL8/IL8-mediated stimulation (PubMed:17244676, PubMed:17580308). In neutrophils, stored predominantly in secondary and tertiary granules (PubMed:18462208). Can also be shedded from the cell membrane (PubMed:12239154, PubMed:18462208). Localizes to lamellar protrusions in spreading neutrophils (PubMed:28807980).
Protein: FTSP_HAEIN
Sequence: MPRLSRRQLLKTAAISTALSTVPAPLLAASREKLVVPPLIEVRRGRPIVLTMQETNYPLDGSHNVTVWGFNGNYLGPTIKIKSGSFAKLNYHNNLPQSVALSIQGLQASGELFGGAARVLKKGESWAPIVPIEQPAASCWYRSATLANSAYQTYRGLAGMWLIEDEQSLKANLPNKYGVDDIPLILQDMEFNNDGLQLFKQNQPHFVGNRLLVNGIEAPYLDVARGWIRLRLLNASLARAYDLRLDNDQEMLLIAQDLGFLPKAKSVKSLVLSPGERAEILVNMMKLTTYLSLAEVNVACTKNKKYVVLRR
What is the function of this protein?
Cell division protein that is required for growth during stress conditions.  May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity).
What are the official names of this protein?
Putative cell division protein FtsP.
What is the protein family that this protein belongs to?
Belongs to the FtsP family.
What are the subcellular locations of this protein?
Periplasm. Note=Localizes to the division septum.
Protein: PIMT_PSEPW
Sequence: MTSQRTRERLIQRLCEEGVSNPKVLDAIRRTPRHLFVDEALAHRAYEDTALPIGHNQTISQPFMVAHMSELLLEAGPLDKVLEIGTGSGYQTAILAQLVERVFSVERIKVLQDRAKERLVELNLRNVVFRWGDGCDGWQALAPYNGIIVTAVAPEVPQALLDQLAPGGRMVIPVGPAGEVQQLMLIVREEQGFSRRVLGAVRFVPLLNGPVA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y758_STRPI
Sequence: MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIGKESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPTLHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHAHVTALASRPKLIGGARAHYPQDAIRKS
What are the official names of this protein?
UPF0340 protein SPH_0758.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: METK1_VITVI
Sequence: MDTFLFTSESVNEGHPDKLCDQVSDAILDACLEQDPESKVACETCTKTNMVMVFGEITTKAKVNYEKIVRDTCRGIGFVSADVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKKPEEIGAGDQGHMFGYATDETPELMPLTHVLATKLGAKLTEVRKNGTCPWLRPDGKTQVTVEYRNEGGAMVPIRVHTVLVSTQHDETVTNEQIAKDLKEHVIKPVIPPQYLDDQTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVASGLARRCIVQVSYAIGVPEPLSVFVDTYKTGKIPDKDILALIKKNFDFRPGMISINLDLKRGGNFRFQKTAAYGHFGRDDPDFSWETVKQLKPEKA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP_METTH
Sequence: MFCYQCSQTVRGRACTIRGVCGKEPTVARLQDNLLFAIKGISAYLYHARELGYTDEEVDAFLERGFYSTLTNVNFDAGEFIDLALEAGEMNIRTMKLLKKAHIDTYGEPEPTEVRVGALEGPAIIATGHSLRALEELLKQTEGTGINVYTHSELLPAHGYPGLRKYPHLAGQLGGPWFDQKDTFSRYTAAILGTSNCVLLPRDDYRDRMFTCGVAALPGVEHLEGYDFSPLIDKALELPPLSEEDATTLTTGFGLSTILSLADKIRELVEDGKIRRFFLVGGCDSPLPRAKYYTEFVRKLPEDTVVLTLACGKYRFNSMDLGDIEGVPRLIDLGQCNDAIVAVELVEALSNLFQMDINELPLSIILSWMEQKAAAILWSLLSLDLKGMYIGPILPGWANEDIVKFLVDNYDLTPIGDPEEDIRKILG
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR15_ARATH
Sequence: MIKNIVISFEEQKEESRGSVEFQVFSFTNKIRRLTSHLELHRKDYLSQRGLRKILGKRQRLLAYLSKKNRVRYKELINQLNIRELKTR
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IF1_BRUC2
Sequence: MAKEEVLEFPGVVTELLPNAMFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPYDLTKGRITYRLK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_ANOFW
Sequence: MEKFLLTAPDGPPSDVERIKQESNYLRGTLKETMEDRITAGIPEDDNRLMKFHGSYLQDDRDLRAERQKQKLEPAYQFMIRVRTPGGVATPEQWLAMDELARKYANGTLKLTTRQAFQFHGVLKWNMKKTLQAINDALLTTLAACGDVNRNVMCNPNPYQSEVHAEVYEWAKRLSDHLLPQTRAYYEIWLDEEKVADTPDVEQEPIYGALYLPRKFKIGIAVPPSNDVDVFSQDLGFIAIVEHGKLAGFNVAIGGGMGMTHGDRTTYPQLAKVIGFCKPEQVIDVAEKVVTIQRDYGNRSVRKHARFKYTIDRLGLDAIKAELERRLGWELEEARPYRFEHNGDRYGWVEGVNGTWHFTLFIEGGRVKDTDDYPLMTGLREIAKVHTGDFRLTANQNLVIANVPSEKKEEMDALIQQYKLTDGKHYSALRRNSLACVALPTCGLAMAEAERYLPTLIDKIEEIVEENGLRDEEITIRMTGCPNGCARHVLGEIAFIGKSVGKYNMYLGAAFDGSRLGKLYRENIGEKEILSELRMLLSRYAKERFDGERFGDFVIRAGIVKEVTDGTNFHD
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: PSB3_DICDI
Sequence: MSIMAYNGGACIVMVGKNCVAIASDLRFGIQQQTISNDFPKVYRINDKCFVGISGLVTDAQTLYQKLVFRHNLYKLREERDMSPRVVSNLLTNMLYEKRFGPYFTEPLICGLEGPDNTPFISGMDLIGASVATDDFLVVGTMTPAMYGVCETLYKKDMNEDDLFETISQCMLASLDRDALSGWGAIVHVITPTQVITKKLLGRQD
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FBPC_ACTPL
Sequence: MNNDFLVLKNITKSFGKATVIDNLDLVIKRGTMVTLLGPSGCGKTTVLRLVAGLENPTSGQIFIDGEDVTKSSIQNRDICIVFQSYALFPHMSIGDNVGYGLRMQGVSNEERKQRVKEALELVDLAGFADRFVDQISGGQQQRVALARALVLKPKVLILDEPLSNLDANLRRSMREKIRELQQRLGITSLYVTHDQTEAFAVSDEVIVMNKGTIMQKARQKIFIYDRILYSLRNFMGESTICDGNLNQGTVSIGDYRFPLHNAADFSVADGACLVGVRPEAIRLTATGETSQRCQIKSAVYMGNHWEIVANWNGKDVLINANPDQFDPDATKAFIHFTEQGIFLLNKE
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL14_ENDTX
Sequence: MIQERTILNVADNSGARKIRCFRVTKGLKRRYASIGDVIHASVQDALPHANVKKGDVVKAVVVRTVKEIRRADGTYIKFDDNATVIINDEGEPKGTRIFGPVAKELRENNYLKIISLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL14_ERYLH
Sequence: MIQMQSNLDVADNSGAKRVQCIKVLGGSKRRTASVGDVIVVSVKEAQPRAKVKKGDVHRAVIVRTKKDVRRPDGSVIRFDSNAAVLVSKNEEPIGTRIFGPVVRELRGRGFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: DADA_BORPD
Sequence: MHVIVLGSGVIGTTTAYYLARQGAKVTVLDRQPEAACETSYANAGQVSPGYSTPWAAPGIPFKALKWLFQKDAPLAIRPDGTLYQWRWMAAMLANCTAGRYTVNKERMLRLAEYSRDCLRELRADTGIQYEARTLGTLQLFRSASQYQAAQRDIQVLDACGVPYELLDSARLQTVEPALARTAHKLAGGLRLPNDETGDCRLFTRRLAQLAAGLGVEFRYGQDVEALVAGGAEIRGVRVGGETLAADRYVAAFGSYTRGFLAPLGLELPVYPVKGYSLTIPLASAEAAPVSTVLDETYKVAITRFDNRIRVGGMAELAGFDLGLNPAHRRTLEHVVTDLYPGCGEVAQAEFWTGLRPMTPDSTPIVGATRYANLFLNTGHGTLGWTMACGSGKVVADLVTGQRPAIRADDLALARYQAAQTRHAGPALGERSAA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: GPMI_HALOH
Sequence: MNRPKPLALIIMDGFGLSEKSDGNAIKQAHTPNLDKFFEEYPDTVLDASGEAVGLPEGQMGNSEVGHLNLGAGRIVYQDYTRINKAIEEGTLPENDALKNAIQHVKDNNSALHLMGLLSDGGVHSHINHLFGLLEMARVKNIEKVYVHPILDGRDTPPRSAEKYLNQLEEKLAELGIGEIATVSGRYYTMDRDNRWDRTKKSYDALVLGEGLEASDAISALKQSYAADKSDEFVIPTVIKKNGQPVGTIKDNDAVIFYNFRADRARQITKALALEEFDEFERPAEHPENLYYVCMAEYDEEFNLPVAFPPLEIKNGFGEILSKEGFKQLRIAETEKYAHVTFFFNGGVEKKYPGEDRVLVPSPKVATYDEKPEMSAYEVTDKLLEKLDEDKYDVIILNFANPDMVGHTGFMDAAVKAVEAVDECLGKIIPRIVDMGGQVLLTADHGNSEKMKDSEGKPHTAHTTNQVPLIYIGGPEGVGVKPGKLADIAPTMLEILGLDTPEEMTGQSLLTR
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: STEL7_DROME
Sequence: MSSSQNNNSSWIDWFLGIKGNQFLCRVPTDYVQDTFNQMGLEYFSEILDVILKPVIDSSSGLLYGDEKKWYGMIHARYIRAERGLIAMHRKYMRGDFGSCPNISCDRQNTLPVGLSAVWGKSTVKIHCPRCKSNFHPKSDTQLDGAMFGPSFPDIFFSLLPNLTSPLDDPRT
What is the function of this protein?
Unknown.  In males lacking the Y chromosome, its strong overexpression leads to the appearance of proteinaceous star-shaped crystals in the primary spermatocytes causing meiotic drive, possibly by interfering with normal casein kinase 2 activity.
What are the official names of this protein?
Stellate protein CG33247.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: H2F2_TRYB2
Sequence: MFRWSWCRLIISKVSAESYVDYLQNSDRELPALSEIFPRHGTGTGELVKFHSLLCEAMKDHNFNYVGIKVVPPTSPPLQCLRATEPVCVPIFSNSFQGSVFSAKQHRIQFVEPLFVIRLGRDPPTQLTANTVPAVCDAFFPGVEFVGSRYPFYPPHTTGFAADLGGCVAVHLGEAVSLGSASLESLGDTNFVVTRREEPIQVGAGKNCLGGPGAAVALAVSYAASMGWPLREKHYIFCSGVGSRSPALAGEYKVNYGAYGSVSASLT
What is the function of this protein?
May play a role in mitochondrial mRNA editing by facilitating the association of the gRNA-binding (GRBC) complex with the RNA editing core (RECC) complex (PubMed:26769962).  However, appears to be dispensable for mRNA editing per se (PubMed:26769962).
What are the official names of this protein?
REH2-associated factor 2.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: APT_BRASO
Sequence: MTFDLDIKNTVRTIPDYPKPGILFRDITTLLADARAFRRAVDELVHPWAGSKIDKVAGIEARGFILGGAVAHQLSAGFVPIRKKGKLPHKTVSMSYALEYGTDEMEMHVDAVQPGERVILVDDLIATGGTAEGAVKLLRQIGATVVAACFIIDLPDLGGAAKLRALDVPVRSLIAFDGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL26_HCMVM
Sequence: MYAVFGLTRSEVTPHEAAAARYKHRGVIDRRGAAMTSRRAPDGGLNLDDFMRRQRGRHLDLPYPRGYTLFVCDVEETILTPRDVEYWKLLVVTQGQLRVIGTIGLANLFSWDRSVAGVAADGSVLCYEISRENFVVRAADSLPQLLERGLLHSYFEDVERAAQGRLRHGNRSGLRRDADGQVIRESACYVSRALLRHRVTPGKQEITDAMFEAGNVPSALLP
What is the function of this protein?
Plays a role in the inhibition of host NF-kappa-B.  This inhibition affects both the canonical and the non-canonical pathways.  Blocks the induction of host IKK phosphorylation.  May also influence the normal phosphorylation state of several tegument proteins including pp28 in virions.
What are the official names of this protein?
Tegument protein UL26.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Note=Also found in dense bodies.