PharMolix/UniProtQA huggingface dataset:
Protein: RNFD_CLOLD
Sequence: MAEAQIKKNIFTISSSPHVRCDESVSKIMWSVCLALTPAAVFGVFNFGIHALEVIITGIIAAVVTEYFVEKVRNKPITITDGSAFLTGLLLSMCLPPDIPPYMVAIGSFIAIAIAKHSMGGLGQNIFNPAHIGRAALMVSWPVAMTTWSKLSASGVDAVTTATPLGILKLQGYSKLLETFGGQGALYKAMFLGTRNGSIGETSTILLVLGGLYLIYKKYINWQIPVVMIGTVGILTWAFGGTTGIFTGDPVFHMMAGGLVIGAFFMATDMVTIPMTIKGQIIFALGAGALTSLIRLKGGYPEGVCYSILLMNAVTPLIDKFTQPVKFGTRR
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Couples electron transfer from reduced ferredoxin to NAD(+) with translocation of H(+) out of the cell.  Essential for energy conservation during autotrophic growth.  Contributes to ATP synthesis during heterotrophic growth.
What are the official names of this protein?
Proton-translocating ferredoxin:NAD(+) oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YXBC_BACSU
Sequence: MSAVTESVLESIISPVTMSEFLEEYWPVKPLVARGEVERFTSIPGFEKVRTLENVLAIYNNPVMVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDFTDLFIPQVRRWIEKLKAELRLPAGTSSKAIVYAAKNGGGFKAHFDAYTNLIFQIQGEKTWKLAKNENVSNPMQHYDLSEAPYYPDDLQSYWKGDPPKEDLPDAEIVNLTPGTMLYLPRGLWHSTKSDQATLALNITFGQPAWLDLMLAALRKKLISDNRFRELAVNHQSLHESSKSELNGYLESLIQTLSENAETLTPEQIFQSQDSDFDPYQSTQLVFRQLLTSYKF
What are the official names of this protein?
Uncharacterized protein YxbC.
What is the protein family that this protein belongs to?
Belongs to the ROX family.
Protein: SPG7_MOUSE
Sequence: MAAALLLLRGLRPGPEPRPRRLWGLLSGRGPGLSSGAGARRPYAARGTPVGPAAAGGHAPQSLLLRILTPSFEGISGLLLKQHIVPNAVRLWPLSGSTLYFNTSRMKQKNKDNDKPKGKTPEDDEEEKRRKEREDQMYRERLRTLFIIALVMSLLNSLSTSGGSISWADFVNEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIESKDRIPVSYKRTGFFGNALYALGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKTGKGVSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIFEQHLKGLKLTQPSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTFNFEYAVERVIAGTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIAYSMVKQFGMAPSIGPVSFPEAQEGLMGIGRRPFSQGLQQMMDHEAKLLVAKAYRHTEKVLLDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQKWIDAEKERQASGEEEAPAP
What is the function of this protein?
ATP-dependent zinc metalloprotease.  Plays a role in the formation and regulation of the mitochondrial permeability transition pore (mPTP) and its proteolytic activity is dispensable for this function (By similarity).
What are the official names of this protein?
Paraplegin, Spastic paraplegia 7 protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL9_BACLD
Sequence: MKVIFLQDVKGKGKKGEVKNVADGYAHNFLIKKGLAVEATSANISALEGQKKKEKKEAAEELKSAKELKKQLEEITVELSAKSGEGGRLFGSVTSKQIADALQKGHQLKVDKRKIELNDAIRSLGYTNVPVKLHPEVQATLKVHVKEQS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GCH4_STAAN
Sequence: MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDEKGINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDKVTRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQNIVDDYKNKILDAMEANASSILYPILKRPDEKRVTERAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: CDPK5_PLABA
Sequence: MCEHKANNKNDGEFVNLKEKNENNHCGNTKSTIADCDDDYSIITLCTKCLSTKTEVNKNKIILDSKALKDSRTKRRSSVNINIDILNNNLNLSPYFDRSQIVQETILMNNDDLEKLYELDKYKLGKGSYGNVVKAINKKTGQAKAIKIIDKKRINNIERLKREILIMKQMDHPNIIKLYEVYEDNEKLYLVLELCTGGELFDKIVKHGSFSEYETYKIMKQIFSALAYCHSKNIIHRDLKPENILYVDSSDDSPIQIIDWGFASKCMNNHNLKSVVGTPYYIAPEILKGKYDKKCDIWSSGVIMYILLCGYPPFNGKNNDDILKKVKKGEFVFDSNYWSKISLDAKELICECLNYNYKERIDVHKIVNHKWFIKFKNYNHITINKHLSKELIEKFKKFHKLCKIKKLAITCIAYQLNKKKFGKMKKTFEAFDHNGDGVLTISEIFQCLKVGDNEIDRDLYYLLKQLDTDGNGLIDYTEFLAACLDHSILEQDAVCRNAFKIFDANGDGIITKDELLNVLSFSNDQMPFSKEIIENVIKEVDANNDGYIDYDEFYKMMSGRQS
What is the function of this protein?
Calcium-dependent protein kinase which acts as a sensor and effector of intracellular Ca(2+) levels probably in part downstream of cGMP-activated PKG kinase (By similarity).  Plays a central role in host erythrocytes and hepatocytes infection cycles (PubMed:32866196).  During the liver stage, involved in sporozoite motility and thus in sporozoite invasion of host hepatocytes, probably together with CDPK1 and CDPK4 (PubMed:32866196).  Involved in merosome egress from host hepatocytes, probably together with CDPK4 (PubMed:32866196).  Required for the release of hepatic merozoites from merosomes in the host blood stream (PubMed:32866196).  During the asexual blood stage, required for merozoite egress from host erythrocytes by triggering microneme secretion (By similarity).  Phosphorylates transporter NPT1 at late schizont stage (By similarity).
What are the official names of this protein?
Calcium-dependent protein kinase 5, PbCDPK5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, secretory vesicle, microneme membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=During the late stages of schizogony, localizes to the cytoplasm in immature daughter merozoites, co-localizes with AMA1 to a subset of micronemes and to the apical region in maturing daughter merozoites, and near the plasma membrane in mature daughter and free merozoites.
Protein: G6PDC_SPIOL
Sequence: MEELVSCHHLPLLCLQSSVPPNGCLTFFQDSACQRCSHSEFSNGHPLNDVSLQNDVAVNPIVAKSIDPSADLQLLPLLESVKEEPTLSIIVVGASGDLAKKKIFPALFALFYENCLPENFTVFGFSRTEMNDEELRTMISKTLTCRIDQRENCGEKMDHFLQRCFYHSGQYNSEDDFSGLDCKLKEKEAGRLQNRLFYLSIPPNIFVDVVRCVSHRASSASGWTRVIVEKPFGRDSDSSRELTRSFKQYLSEDQIFRIDHYLGKELVENLSVLRFSNLVFEPLWSRNYIRNVQLIFSEDFGTEGRGGYFDNYGIIRDIMQNHLLQILALFAMETPVSLDAEDIRNEKVKVLRSMKPLKLQDVVVGQYKGHSKGNKSYSGYTDDPTVPNNSVTPTFAAAALFIDNARWDGVPFLMKAGKALHTKRAEIRVQFRHVPGNLYKKTFGTDLDKATNELVLRVQPDEAIYLKINNKVPGLGMRLDRTDLNLCYSTRYRGEIPDAYERLLLDAIEGERRLFIRSDKLDAAWSLFTPLLKELEEKKVAPELYPYGSRGPVGAHYLAAKHNVRWGDLSGEDS
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, chloroplastic, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARGC_BRUMB
Sequence: MKPKIFIDGEHGTTGLQIRTRLAERDDLEVISIPEAERRNKDLRADYLRAADIAILCLPDDASKEAVSLLEGHNSTRIIDTSTAHRVHPDWAYGFAELAKGQRERIAEARLVANPGCYPTGAIALVRPLRDAGLLPADYPVSVNAVSGYTGGGKQLIAQMEDRNHPDYLAANNFLYGLPLKHKHVPELQLHGRLDRRPIFSPSVGRFPQGMIVQVPLFLSELEGSPSLAKVHAVLTEHYAGQDIVEVVPLEESAKLPRVDAEELAGKDGMKLFVFGTEDHGQVNLVALLDNLGKGASGAAVQNMNLMLGK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_ROSDO
Sequence: MTRIDDKFAQLAKDGKKAFVAYVMAGDPNYETSLEVVKGLPAAGVDVIELGLPFTDPMADGPTIQLAGQRALEAGMTLQKTLDLARAFRKDDQTTPIVMMGYYNPIYSRGVDRFLAEAKDAGIDGLIVVDLPPEEDSELCLPAQAAGLNFIRLATPTTDDKRLPRVLQNTSGFVYYVSITGITGAAEAQAVDVGPEVARIKSAAALPVIVGFGVNTPEKSKAIAEVADGVVVGSAIVGKIGAGQSVSDVLAFVKTLADGAHSV
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RR14_PHAAO
Sequence: MARKSLIQREKKRQKLEQKYYWIRQSLKKEISKVPSLREQWKIHGKLQSSPRNSAPIRLHRRCFLTGRPRANYRDFGLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: THIG_ECOHS
Sequence: MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDARWLLPDPIETLKAAEMLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAKAFRLAVEAGLLARQSGPGSRSHFAHATSPLTGFLEASA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_I71A1
Sequence: MDSNTVSSFQDILLRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGLKFEEIRWLIEEVRHRLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LUTA1_BACAC
Sequence: MKVSLFITCLSDVFFPQVGKSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAKQMIKAFEHSEYIVTPSGSCASMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFVVNILGKNDWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGLDIKELPYCQDCCGFGGTFAVKMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRENKNIQVLHVAEVLAKGLNK
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A 1.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: PTH_DECAR
Sequence: MNAPRLIVGLGNPGPEYEATRHNVGFWFVDQLADKLKVSLAPQAKFFGRAARTGETWLLQPTTFMNRSGQAVAALANFYKIPADEILVIHDELDLPPGGIRLKQGGGNGGHNGLKDIQAKLGTPDFWRLRLGIGHPRTLNLSQQVVDFVLHQPRKEELPDIEHALARCLLAWPKLAAGDFAGAQQQLHGKAV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_MYCTA
Sequence: MTDRARLRLHDTAAGVVRDFVPLRPGHVSIYLCGATVQGLPHIGHVRSGVAFDILRRWLLARGYDVAFIRNVTDIEDKILAKAAAAGRPWWEWAATHERAFTAAYDALDVLPPSAEPRATGHITQMIEMIERLIQAGHAYTGGGDVYFDVLSYPEYGQLSGHKIDDVHQGEGVAAGKRDQRDFTLWKGEKPGEPSWPTPWGRGRPGWHLECSAMARSYLGPEFDIHCGGMDLVFPHHENEIAQSRAAGDGFARYWLHNGWVTMGGEKMSKSLGNVLSMPAMLQRVRPAELRYYLGSAHYRSMLEFSETAMQDAVKAYVGLEDFLHRVRTRVGAVCPGDPTPRFAEALDDDLSVPIALAEIHHVRAEGNRALDAGDHDGALRSASAIRAMMGILGCDPLDQRWESRDETSAALAAVDVLVQAELQNREKAREQRNWALADEIRGRLKRAGIEVTDTADGPQWSLLGGDTK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_RICPR
Sequence: MKQILNPLKNSNKIPIWFMRQAGRYLPEYKKVRETTKNFLDFCYDVNKATEVTLQPIRRYGLDAAIIFSDILVLPNALGWEVDFKENIGPVLKQFKSQKDFQYLQRDSNNKLEKVYKIIKKVKEKLPSNTSLIGFAGSPWTVMSYMLEGKGKRDFRTSKKFIYENKILAKDLLNFITEKTSDYLINQVKSGVDLLKIFDSWSGVLAEDDFTEFVIEPTKKIILKVKEVFVKTPIITFPKGAGLLYEKFIEEVPIDILAVDQMVPLEKMKEWSNKVIIQGNLDPVILLTNKEIIKEKTYKILQAMKGKNFIFNLGHGILPETHPENVEFLTQYVRLYEQKNSNSTF
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTR8_HALS3
Sequence: MGESARGGGSAETTGGLAAAVKTYLEYTPTGESIPAAAWRRRHRNVRVFVLAHIPLLLALGLYEGTESAVTGATIPPTPGILIAAELGIVGALVGLASIPSVSRRGRTALASTAVLASSVVLVQFSGGFIEAHFHFFVGMAVIAVYEDWLPFALGLVYVVFTHGVFGMINAERVYNHTAAINNPWVWGGIHGAFVLLLAGALMANWYSTERSREASQKRLEEARQKAQQVEDLEARQAEIEAEKAEAKRLKADAEEAREAAEAQQREVAALNERLEATANTYGAAMARAADGDLSVRLDPDVENDAMAAIAASFNEMLDETETTIREIQAVASDVAAASEDADAGVVEIEDASGQVSETVQEIAAGADEQREKLETVSGEMTDLSAAIEEVAASADSVAERSHETAAVAGDGEQTAEQAIADSRTVQSAVESTVQNVEALDDQLAEISEIVDLISDVAEQTNMLALNANIEAARADKSGDGFAVVADEVKDLAEETRASAGDIEALVADIDAQMQATVTEARTADESVQDAISAVDAVVDAFGTVAENAEETDTGVQEISTTTDDQAASTEEAVSMIAEVSDISTATAADAQQASTAAEQQTTAAATISENTAALREQADRLQGLVSTFDVHDESASTAARSE
What is the function of this protein?
Potentially involved in chemo- or phototactic signal transduction.
What are the official names of this protein?
Transducer protein Htr8.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MZT1_TAEGU
Sequence: MASNAASLNAVRETMDVLFEISRILNTGLDMETLSICVRLCEQGINPEALSSVIKELRKATEALKAAENMTG
What is the function of this protein?
Required for gamma-tubulin complex recruitment to the centrosome.
What are the official names of this protein?
Mitotic-spindle organizing protein 1, Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1.
What is the protein family that this protein belongs to?
Belongs to the MOZART1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle.
Protein: DPIA_ECOLI
Sequence: MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARMMIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVFDYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGIDPLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGRPQRIYHSG
What is the function of this protein?
Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance.  Could be involved in response to both the presence of citrate and external redox conditions.  Regulates the transcription of citCDEFXGT, dpiAB, mdh and exuT.  Binds specifically to the dpiB-citC intergenic region.
What are the official names of this protein?
Transcriptional regulatory protein DpiA, Destabilizer of plasmid inheritance.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGAT2_HUMAN
Sequence: MRFRIYKRKVLILTLVVAACGFVLWSSNGRQRKNEALAPPLLDAEPARGAGGRGGDHPSVAVGIRRVSNVSAASLVPAVPQPEADNLTLRYRSLVYQLNFDQTLRNVDKAGTWAPRELVLVVQVHNRPEYLRLLLDSLRKAQGIDNVLVIFSHDFWSTEINQLIAGVNFCPVLQVFFPFSIQLYPNEFPGSDPRDCPRDLPKNAALKLGCINAEYPDSFGHYREAKFSQTKHHWWWKLHFVWERVKILRDYAGLILFLEEDHYLAPDFYHVFKKMWKLKQQECPECDVLSLGTYSASRSFYGMADKVDVKTWKSTEHNMGLALTRNAYQKLIECTDTFCTYDDYNWDWTLQYLTVSCLPKFWKVLVPQIPRIFHAGDCGMHHKKTCRPSTQSAQIESLLNNNKQYMFPETLTISEKFTVVAISPPRKNGGWGDIRDHELCKSYRRLQ
What is the function of this protein?
Plays an essential role in protein N-glycosylation.  Catalyzes the transfer of N-acetylglucosamine (GlcNAc) onto the free terminal mannose moiety in the core structure of the nascent N-linked glycan chain, giving rise to the second branch in complex glycans.
What are the official names of this protein?
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, Beta-1,2-N-acetylglucosaminyltransferase II, GlcNAc-T II, GNT-II, Mannoside acetylglucosaminyltransferase 2, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 16 (GT16) protein family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: PEPE_SHEB2
Sequence: MTINALLLSSSRVGDTPYLAHAIPFIKPLTTNAQKWIFIPYAGVSMSYDTYLASVVTGLSELELDISGIHQHPDPQQAIKDADGILIGGGNTFHLLHQLYRYDLVTLIGEQVALGKPYIGWSAGSNVSGLSIRTTNDMPIIEPPSFKALNLVPFQLNPHYSNYQAPGHNGETRAQRLLEFTKVDPLTPVVGIVEGSALWRQGDKLSLLGDQPAYLFCGEQQEIPIPVGSDLSHLLKA
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_GRABC
Sequence: MVIRHDWSREEVRSLLDLPFPELLFRAAAIHRACFDPREVQISTLLSIKTGGCPEDCAYCPQAAQYDTGVEASRLMRVDAVLEEARAAKAAGASRFCMGAAWRSPKERDMDTVCEMIEGVKALGMESCVTLGMLTDQQALRLKQAGLDYYNHNLDTSPEYYGAVISTRTYEDRLETLAHVRDAGINVCCGGILGLGEGLDDRAGLIVALANLPRHPESVPINALVQVEGTPLKGQEPVDTIDFVRMIAVARITMPHARVRLSAGREAMTDEAQALCFLAGANSIFYGEKLLTTGNPAAERDRALLSRLGMRLV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: NKAI4_MOUSE
Sequence: MGFCSGRCTLLALCALQLVTALERQVFDFLGYQWAPILANFTHIIVVILGLFGTIQYRPRYIVVYVVWAAVWVTWNVFIICFYLEVGGLSKDSELLTFNLSGHRSWWEEHGPGCLHEEEATAGLGALHGQSLVVGAGCAMVHSYVEALHSGLQILLALLGFVYGCYVVSVLTEEEDSFDFIGGFDPFPLYHVNEKPSSLLSKQAYLPA
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4, Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 4, Protein FAM77A.
What is the protein family that this protein belongs to?
Belongs to the NKAIN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASIP_COLPO
Sequence: MDVTRLLLATLLVFLCFFTVYSHLPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKKSKHISRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRDSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: ORF4_SPV1R
Sequence: MSNFVKKNHNVENYFISKEFIPFTTEKASFINLPNHNRHIGFWLSNKFIYPSEKHSKQVAIGLIYDNSYPIVKYDENLKRHIWKYLTGTELINLYNQYKQNYFTKMKKALFSSEPKKVKANNNNNNLTNWSVEKEQELINDLKDLN
What are the official names of this protein?
Uncharacterized protein ORF4, Gene 4 protein.
What is the protein family that this protein belongs to?
Belongs to the plectrovirus ORF4 family.
Protein: HSLU_PHOPR
Sequence: MSEMTPREIVHELDRHIIGQDKAKRAVAIALRNRWRRMQLPEELRVEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVETIIRDLTDVAVKMTHQQAMSKVQFRAEELAEDRILDILLPPARDQWGQNEENDTDSSTRQSFRKKLREGKLDDKEIEMDIAAPQMGVEIMAPPGMEDMTNQLQGMFQNLAGNTSKKRKMKIKDAIKAATEEEAAKLVNQEELKEQAIFSVENNGIVFLDEIDKICKRGDSSGPDVSREGVQRDLLPLVEGSTVSTKHGMVKTDHILFVASGAFQMSKPSDLIPELQGRLPIRVELEALTSHDFKRILTEPKASLTEQYKALMATESVNIDFSEDGINKIADAAWQVNERTENIGARRLHTVMERLMEELSFDATDRSDELLIIDEAYVNERLDELVENEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB4_ARATH
Sequence: MADLVTVVKKTEEEWRAVLSPEQFRILRQKGTETPGTEEYDKFFEEGIFSCIGCKTPLYKSTTKFDAGCGWPAFFEGLPGAINRAPDPDGRRTEITCAVCDGHLGHVHKGEGYSTPTDERLCVNSVSINFNPAKPSSIT
What is the function of this protein?
Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins.  Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation.  MSRB family specifically reduces the MetSO R-enantiomer (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase B4, AtMSRB4, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.