PharMolix/UniProtQA huggingface dataset:
Protein: GXLT2_MOUSE
Sequence: MKLRSKAAALLLLALAVLLLALLSLRARRDPEPPGFPARPEAAPQRRHAPVPTLPPEPRAFPGAAGRRSPRRQPPRLRPRAGRPRAASREKLARRPGETRSLHSVPPELWIHLAVVACGNRLEETLVMLKSAVLFSHRKMRFHIFTEDALKPEFDKQLRQWPDSYTKKFEHRLYPITFSVGNPQEWKKLFKPCAAQRLFLPAILKDVDSLLYVDTDVLFLRPVDDIWKLLRQFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNLTRIRNTQFKNSLIPAGLAWEEMLLPLYQKYKSAITWGDQDLLNIIFYYNPECLYVFPCQWNYRPDHCMYGSNCKEAEREGVSVLHGNRGVYHDDKQPTFRALYEAIRDFPFQDNLFQSMYYPLQLKFLETVHTLCGRIPQVFLKQIEKTMRRAYEKHVIIHMGPNPMS
What is the function of this protein?
Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.
What are the official names of this protein?
Glucoside xylosyltransferase 2, Glycosyltransferase 8 domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: FGF1_DANRE
Sequence: MTEADIAVKSSPRDYKKLTRLYCMNGGFHLQILADGTVAGAADENTYSILRIKATSPGVVVIEGSETGLYLSMNEHGKLYASSLVTDESYFLEKMEENHYNTYQSQKYGENWYVGIKKNGKMKRGPRTHIGQKAIFFLPRQVEQEED
What is the function of this protein?
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.  Functions as potent mitogen in vitro.  Acts as a ligand for FGFR1 and integrins.  Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades.  Binds to integrins.  Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
What are the official names of this protein?
Putative fibroblast growth factor 1, FGF-1, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, HBGF-1.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery (By similarity).
Protein: 5NTD_BOVIN
Sequence: MNPGAARTPALRILALGALLWPAARPWELTILHTNDVHSRLEQTSEDSSKCVNASRCVGGVARLATKVHQIRRAEPHVLLLDAGDQYQGTIWFTVYKGTEVAHFMNALGYDAMALGNHEFDNGVEGLIDPLLKEVNFPILSANIKAKGPLASKISGLYSPYKILTVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEVDKLIAQKVKGVDVVVGGHSNTFLYTGNPPSKEVPAGQYPFIVTSDDGRKVPVVQAYAFGKYLGYLKVEFDEKGNVVTSHGNPILLNSSIPEDPNIKADINKWRVKLDNYSTQELGKTIVYLDGTAQSCRFRECNMGNLICDAMINNNLRHPDEMSWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQATGEFLQVGGIHVVYDISRNPGDRVVKLEVLCTQCRVPSYEPLRMDKVYKVILPSFLVSGGDGFQMIKDEKIKHDSGDQDINVVSGYISKMKVLYPAVEGRIQFSAGSHCCGSFSLIFLSVLAVIIILYQ
What is the function of this protein?
Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate (PubMed:8340354, PubMed:10825541).  Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms (By similarity).  Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN (By similarity).
What are the official names of this protein?
5'-nucleotidase, 5'-NT, 5'-deoxynucleotidase, Ecto-5'-nucleotidase, IMP-specific 5'-nucleotidase, Thymidylate 5'-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the 5'-nucleotidase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: DNLI_ANASK
Sequence: MLLAELAEVSRAVAATPARLEKVALLSEALRRLAPDERAVGASWLAGDLAGGRVGIGAATLRAALEAAPPGAAGPGLTVGEVDAALRRIAAAAGPGSGAARRRELDALLARAGDPERRFLAALVLGELRQGALEGVLSDAVARVAGLPGAEVRRAAMLAGALPPVAEAALAEGAAGLARFRLRVGEPVSPMLAQTAAGVDEALRALGGEAALEWKLDGARIQAHRDGDEVRVFSRSLREVTAAVPEVVALLRAAPEPLLVLDGEAIALRADGTPEPFQVTMRRFGRKLDVERLAPDLPLTAFFFDALVAGGGELLGAPERERWAALERAIPAERRVPRLVTGDAAEARAFLEEALARGQEGVVAKALDAPYEAGRRGAAWLKVKRAHTLDLVVLAAEWGSGRRRGWLSNLHLGARDPATGEFVMLGKTFKGMTDAMLAWQTERLKALATGPLDAWQVPVRPELVVEVAFDGIQASPRYPGGLALRFARVKRYREDKRPEDADTIETVRGLYGG
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
Probable DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: RSMG_DESHY
Sequence: MLPEHQELLGRLTRQRLNIELSGDQIEKFSIYADRLVEWNEKVNLTSITEPEEIILKHFVDSLALLSLVQGKRLADIGTGAGFPGIPLKILLPEVEVYLVDSLAKRLDFLETVIKELKLTKVQTVHARAEDFARDPHYRETFDCVTSRAVARLPVLLEYAVPLLKKGGYFLAAKGSQAQEEVMESKKALTVLGAEIKDIKLFNLGAEAEHRAIILVEKTSSTPPAYPRKAGTPGKKPLV
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFEU_SHIFL
Sequence: MTSRSRQAAYSGIFINETTGEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLEQAVDSALQRGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLATAVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFDMSAVLSTHSLFGTLMEGIFGYQEAPSVSEVAVWFIYLIPALVAFALPPRAGATASRSA
What is the function of this protein?
Uptake of Fe(2+) ions across the membrane.
What are the official names of this protein?
Ferrous iron permease EfeU, Fe(2+) ion permease EfeU, Ferrous iron uptake protein.
What is the protein family that this protein belongs to?
Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ERA_SALSV
Sequence: MSTDKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGPYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: RNFH_HAHCH
Sequence: MDKLKIQVEVAYALPEQQKIIPLAVVEGTTAYEAVQMSGITHFFPQIELDSAKMGIFGKSIPEPKSHALREGDRVEIYRPLKIDPKQARLNRAKKG
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: PSTB_THEMA
Sequence: MEPIIEIENFSAYYGEKIAVKNVTMKIFKNQITAIIGPSGCGKTTLLRSINRMNDHLPGFRVEGKIYFKGQDIYDPQLDVTEYRKRVGMVFQKPTPFPMSIYDNVAFGPRIHGVKSKHILDRIVEESLKKAALWDEVKSELNKSGTRLSGGQQQRLCIARALAVEPEVILLDEPTSALDPIATQRIEKLLEELSENYTIVIVTHNIGQAIRIADYIAFMYRGELIEYGPTREIVERPKNRLTEEYLTGKIG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUSB_SULDN
Sequence: MATRHQARMAVVSLLYAFDLGNGNIAEHTDEILEEKKIRNKQKDFALTLYEGVMANITPVDEAIVKHLKDWDFERLGAIERATLRLATYEILFGELDSAVVINEAVEITKAFGTEQSPKFINGVLDAISKDK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: VARD_VIOAR
Sequence: GLPICGETCVGGSCNTPGCSCSWPVCTRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Varv peptide D.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: IVBI4_PSEPO
Sequence: MSSGGLLLLLGLLTLREGLTPVSSKDRPDFCELPDDRGPCRGIFHAFYYNPDQRQCLEFIYGGCYGNANNFKTIDECKRTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Blackelin-4.
What are the subcellular locations of this protein?
Secreted.
Protein: CDSA_RICPR
Sequence: MITQKEKEHLAKDKQNIYLRIISGIALVSLFVIAILCLKTLFYILMILVGLGMLSEWYNMTYPSINYLLIGLIIIPIPISLLIFLSMEESNRLVIMLYFCILWSVDTFAMIGGKTFKGIKLAPKISPKKTWTGLITGTVSAGLVSVLVSLIPNYHIEHYYFSNKIYLFIISCILALIAQSSDLFISYFKRKFNIKDSGHIIPGHGGVLDRFDSIILTAPVFFCINIYL
What are the official names of this protein?
Phosphatidate cytidylyltransferase, CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CTP:phosphatidate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SRP54_HUMAN
Sequence: MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:34020957).  As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane (PubMed:34020957).  Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes (PubMed:34020957).  Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA (PubMed:28972538, PubMed:34020957).  Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA (PubMed:34020957).  SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER (PubMed:34020957).  Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA (By similarity).  Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development (PubMed:28972538, PubMed:29914977).
What are the official names of this protein?
Signal recognition particle subunit SRP54, Signal recognition particle 54 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Endoplasmic reticulum.
Protein: Y1401_STAHJ
Sequence: MDLNFDLYMNGVVEQARNEIENAGYEQLTTADEVDKVLQQNGTSLVMVNSVCGCAGGIARPAASHALHYDKLPDRLVTVFAGQDKEATQQARDYFEGYAPSSPSFALIKDGKITEMIERHQIEGHDVMDVINQLQGLFDKYCDER
What are the official names of this protein?
UPF0403 protein SH1401.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: P53_CHICK
Sequence: MAEEMEPLLEPTEVFMDLWSMLPYSMQQLPLPEDHSNWQELSPLEPSDPPPPPPPPPLPLAAAAPPPLNPPTPPRAAPSPVVPSTEDYGGDFDFRVGFVEAGTAKSVTCTYSPVLNKVYCRLAKPCPVQVRVGVAPPPGSSLRAVAVYKKSEHVAEVVRRCPHHERCGGGTDGLAPAQHLIRVEGNPQARYHDDETTKRHSVVVPYEPPEVGSDCTTVLYNFMCNSSCMGGMNRRPILTILTLEGPGGQLLGRRCFEVRVCACPGRDRKIEEENFRKRGGAGGVAKRAMSPPTEAPEPPKKRVLNPDNEIFYLQVRGRRRYEMLKEINEALQLAEGGSAPRPSKGRRVKVEGPQPSCGKKLLQKGSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity).
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CENPK_HUMAN
Sequence: MNQEDLDPDSTTDVGDVTNTEEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPETIPLTEDVLITLGKEEFQKLRQDLEMVLSTKESKNEKLKEDLEREQRWLDEQQQIMESLNVLHSELKNKVETFSESRIFNELKTKMLNIKEYKEKLLSTLGEFLEDHFPLPDRSVKKKKKNIQESSVNLITLHEMLEILINRLFDVPHDPYVKISDSFWPPYVELLLRNGIALRHPEDPTRIRLEAFHQ
What is the function of this protein?
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.  Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore.
What are the official names of this protein?
Centromere protein K, CENP-K, Interphase centromere complex protein 37, Protein AF-5alpha, p33.
What is the protein family that this protein belongs to?
Belongs to the CENP-K/MCM22 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Protein: RIMK_STRM5
Sequence: MKLAILSRNSTLYSTRRLVEAARARGHTVRILDPLRCYMRIAADGFSMHYKGRPMTGVDMVIPRIGASITRYGTAVLRQFELMGARTPNPSDAILRSRDKLRAHQLLAAKGIDMPVTVFGDNPDDTVDLLSMLGPPPHVVKLNEGTQGRGVILTEKASASRGIVEALRGLYANFLMQEFIGEAKGADLRCFVVGDQVVASMQRQAPEGDFRSNLHAGGTAVAAKASRAEQQVAVRSAKALGLSVCGVDLIRSARGPLVLEINSTPGLEGIEAACGVDVATRIIEHVEKLRKP
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: ENGB_LEGPH
Sequence: MPINLYSKAVFLKSAARVNQLPEDSGYEVAFAGRSNAGKSSALNCLTNNKNLARTSKTPGRTQLINLFSLDEQRRLVDLPGYGYAKVAMEVKLEWQKNLAHYLEARQCLRGLILLMDVRHPLKDLDQILVNWALHRELPVHILLTKADKLSRSEVKNAVLKVRQYYELAEHLVSVQAFSSVKKDGVEELISLLDRWYEWN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: OXAA_AQUAE
Sequence: MMDNDNQFWKRFLIFTILMFLFITAYELFYIYYVKPSQPQKTEKKEVVKKEEFKNVNLPQLMLGTFREKQEYKNTKTVKLGIYSLELSEKGGKILRFIDQKYGFDLISKAERELKIFPLEIFTGNPDLDQKLNFGEYEIKEGKNSVELIHKELKVKKILSYKNGAIHLSVEGLKPPFWVFVGSPPDDEAFYTHVGPVLKINGEVVRLDVDDLKGINEFEGNIEFGGEESRYFFKGAKDYQKHIVYKVKLGDKFVSLSTFLYDGEKTIYLGAKDYARLRELGLVDTLDWGTLKIIVKPLFLFLYWIYEHTGSWVLSILVLTFIVRIFLFPLGYKSVVSMQKLQELAPKMEKIKQKYKDDPVKMQEEMMKLYAETGFNPMAGCLPILLQIPIFFALYKVLIITVDLKVSSFLWIPSLADKDPYYILPVIMGLTMILQQKMTPSPDPKQALVGYITSVAFTLLFINFPAGLVLYWTLNNVFNIIQNYLIKEVLLKDKSKGGSKKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TBP_ASFB7
Sequence: MEDETELCFRSNKVTRLEMFVCTYGGKITSLACSHMELIKMLQIAEPVKALNCNFGHQCLPGYESLIKTPKKTKNMLRRPRKTEGDGTCFNSAIEASILFKDKMYKLKCFPSTGEIQVPGVIFPDFEDGKNIIQQWVDFLQHQPIEKKIQIIEFKTIMINFKFQINPVSPRVIIHLKKFAALLEHIPTPYPIREIKPPLEDSKVSAKFMVSPGKKVRINVFLKGKINILGCNTKESAEIIYTFLKDLISVHWQEILCVLPVPD
What is the function of this protein?
Putative TATA-binding protein.
What are the official names of this protein?
Putative TATA-binding protein pB263R, TBP.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B263R family.
Protein: TSDB_STUS1
Sequence: MKSIHWPLAGVAALLLSMQAQAADGQKIYTQGGANPAAMACATCHGADAMGMAAAGFPRLAGIDAGYSRKQLDDFRSGARSNPIMQPIAAALSDEEMDAVAATLEAMPAPDFAAIGRSEAAEGVGARLALRGAWERNIPECVACHGPAGMGVGASFPPLAGQSAQYLGAQLNAWRQGTRKNDPNDLMGHIARAMSDDEVQAVAEYFANVGQKETGQ
What is the function of this protein?
Acts as an electron acceptor for the thiosulfate dehydrogenase TsdA.
What are the official names of this protein?
Thiosulfate dehydrogenase electron acceptor.
Protein: ERA_CAMJE
Sequence: MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVMHEKNQIIFIDTPGLHESGATLNQLLVQSAIKSMGDCDVILFVASVFDSTKDYENFLSLNPQVPHIITLNKVDLTDNATLLKKLSEYAKFSQHFKAIIPYSSKKKSYKKGLLDEIVKYLDEHEYFYDPEFLSASSEKEIYRDFILESIYENLSDELPYSSEVLIHRTKDTPNLLILEANIITDTNSHKGMLIGKEGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: PEPT_YERPB
Sequence: MDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMATLPANVSWPVPTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNVPHGDIRIAFTPDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGVMVNALSLATRYHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKRVGKGLHRDCYIEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRISELTAKRAKES
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_SYNFM
Sequence: MLTDILKKIFGSQNERILKRIAPLVDEINSYEPVMRKLSDAALKAKTPEFKQRIANGEPLDDLLPEAFAVAREGAVRTLGMRPFDVQMIGGIVLHEGMIAEMKTGEGKTLVAVMPIYLNALTGRGVHLVTVNDYLARRDSEWMGQVYKFLGLSVGCIVHGLDDPERKEAYGADVTYGTNNEYGFDYLRDNMKFRIEDMVQRELNYAIVDEVDSILIDEARTPLIISGPAEKSTALYYNINRIIPQLKPETHYTKEEKSRTVALTEDGVTRTEKLLGVDNLYDPRQIDILHHVQQALRAHVLFKRDVDYIVKDGKVIIVDEFTGRLMPGRRYSEGLHQALEAKENVHIENENQTLASITFQNYFRMFDKLAGMTGTAETEAAEFAKIYKLEVVVIPTHRKMIREDYADCIYRTEAEKFRAVAEEIKEAYAVKRPVLVGTVNIAKSEKLSGILKRQGVPHQVLNAKHHEKEAEIVALAGQPGAVTISTNMAGRGTDIVLGPGVVDVGGLHIIGTERHEARRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRIFAADRLSGLMQRIGMKEDEPIEHRLITKAIENAQSKVEAQNFSIRKQLLEYDDVMNQQREVIYRQRREALQGENLKPVVLDMIEDLLEGILAETADEKHYAEDWDLEKINSEVLRLFGLQMNLTVESLGDIEYEEFRDSLLERLTKRYEAREQEFGESMMRELESYLLLQTVDTYWKDHLLNMDHLKEGIGLRGYGQQDPLIAYKREGHALFDEMIERIKEETIRLLFHIQIQREEQLDELRKEQEDQPMFFGPAEGAGQKPQTRKDRKVGRNDPCPCGSGKKYKKCCGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: GLSA_SHEB5
Sequence: MPELALLEEVVEKVRPLLGQGKVADYIPALASVDAGKIGIAVTTVDGETLGAGDYLEPFSIQSISKVFSLTLALTLYEEAEIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRQLSQNDKVCFDKQVADSEYQHSARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSKAMLYLANRGKSITGTELISQVQTRQLNALLATSGLYDGAGEFAYRVGMPGKSGVGGGIIAVIPGELSICVWSPELDGNGNSLAGTAMLEHLSQRLGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: ACSL1_RAT
Sequence: MEVHELFRYFRMPELIDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEVTGTTEGVRRSAVLEDDKLLLYYYDDVRTMYDGFQRGIQVSNDGPCLGSRKPNQPYEWISYKQVAEMAECIGSALIQKGFKPCSEQFIGIFSQNRPEWVTIEQGCFTYSMVVVPLYDTLGTDAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYDNDLVERGQKCGVEIIGLKALEDLGRVNRTKPKPPEPEDLAIICFTSGTTGNPKGAMVTHQNIMNDCSGFIKATESAFIASPEDVLISFLPLAHMFETVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSVKRWLLDFASKRKEAELRSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPCNYIKLVDVEDMNYQAAKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAIVVPDVEILPSWAQKRGFQGSFEELCRNKDINKAILEDMVKLGKNAGLKPFEQVKGIAVHPELFSIDNGLLTPTLKAKRPELRNYFRSQIDELYSTIKI
What is the function of this protein?
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:8978480, PubMed:10198260, PubMed:10749848, PubMed:28209804).  Preferentially uses palmitoleate, oleate and linoleate (By similarity).  Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs) (PubMed:28209804).
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase 1, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 1, LACS 1, Long-chain-fatty-acid--CoA ligase, liver isozyme, Phytanate--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.