PharMolix/UniProtQA huggingface dataset:
Protein: SYV_CHRVO
Sequence: MEQLAKSYEPGDLERRWYQHWEQAGYFKPSMDTSKPSFAIQLPPPNVTGTLHMGHAFNQTIMDGLTRFYRMKGHNTLWVPGTDHAGIATQIVVERQLADQGLNRHDMGREAFTSKIWEWKEKSGGTITSQMRRVGCSVDWDREYFTMDDVRAEVVTEVFVRLYEQGLIYRGKRLSNWDAKLGTAISDLEVVSEEEDGHMWHIKYPVVGSDEFVTVATTRPETLLGDVAVAIAPDDERYLHLVGKQLELPLTGRTIPVIADSYVDKEFGTGFVKITPAHDFNDYEVGKRHGTQLINVMSLEAKILAKAQIFGFDGSAQGAIELPAAYAGLTAQEARKAMLADLQAQGLLLETKPHKLMVPRGDRTGTVIEPLLTDQWFVAMNKVAEGDATGQSIAAKAIEAVESGEVRFVPENWVNTYNQWMKNIQDWCISRQLWWGHQIPAWYDEDGNIYVGRTEAEAQAKAGGKTLRREQDVLDTWFSSALVPFSTLGWPEETPDLKAFLTSNVLVTGYEIIFFWVARMIMMTKHFTGKVPFKDVYIHGMVRDHEGKKMSKSEGNVIDPVDLIDGIALEPLVEKRTTGLRRPEKAPQIAKATEKLFPEGIPAYGTDALRFTMASYATLGRSVNFDFKRAEGYRNFCNKLWNATRFVMMNVDGKDCGQDESLPLEYSFVDQWIIGRLQQAEIDVTNALETYRFDIAAQVIYEFIWNEYCDWYVELAKVQIQGGNEAQQRATRRTLVRVLEVALRLNHPLMPFITEELWQTVAPLANAKKTESLMLAPWPVADESKISAAANARMEAFKDMVNAVRNLRGEMGIGPAVKAPLFIETADASIADFVPYLKLLARLTEGTLVAKLPEDDAPVAMSGEARLMLKVEVDKAAETARLRKEQGKVEAELAKLTAKLEKPGYVDKAPAHLVERDKAQLAELNDKLEKIRVQLVKLA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARU_STAAN
Sequence: MDYQTFEKVNKFINVEAYIFFLTQELKQQYKLSLKELLILAYFYYKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRKKIACVINELDKIIKGFNKERDYIKYQWAPKYSKEFFILFMNIMYSKDFLKYRFNLTFLDLSILYVISSRKNEILNLKDLFESIRFMYPQIVRSVNRLNNKGMLIKERSLADERIVLIKINKIQYNTIKSIFTDTSKILKPRKFFF
What is the function of this protein?
Positive regulator of RNAII and RNAIII in a cell density-dependent manner.  It can contribute to the expression of virulence genes controlled by agr.  May also regulate target genes via an agr-independent pathway (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarU, Staphylococcal accessory regulator U.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_TRYBR
Sequence: MVSGVTYLKRGAVFGSGAFGTALACVLAKKCESVSVWHMNANEARVVNQKHENVYFLPGAPLPANLTFTADAEECAKGAEIVLFVIPTQFLRGFLQKNSHILRNHVVSRNVPVVMCSKGIERSSLLFPAQILEEFLPNYPIGVIAGPSFAIEVAKGMLTNVCTAAADIDMARKIQRIMTTSDGSFRCWATTDVIGCEIASAMKNVLAIASGALKGLGTENNARAALISRGLLEIRDLTLALGGTGEAVFGLPGLGDLLLTCSSELSRNFTVGMKLGKGISLEEIKRTSKAVAEGVATAEPLERLAKKHNVHLPICHEVYNVLYANGCAKRSFKKLNSCKLADEGLPALPRTSKM
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Glycosome.
Protein: LEUD_MYCBO
Sequence: MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDPAFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDIFRGNAGKAGLLAAEVAQDDVELLWKLIEQSPGLEITANLQDRIITAATVVLPFKIDDHSAWRLLEGLDDIALTLRKLDEIEAFEGACAYWKPRTLPAP
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PTG3L_MOUSE
Sequence: MERQPARTLWYDRPKYVFMEFCVEDSTDVSVLIEDHRVVFSCRNGDGVELYNEIEFYAKVNSKDSQDKRSGRSITCFVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDDEVELAQVEHYAEDDSDS
What are the official names of this protein?
Putative protein PTGES3L, Prostaglandin E synthase 3-like.
What is the protein family that this protein belongs to?
Belongs to the p23/wos2 family.
Protein: RIPA_CORDI
Sequence: MSLPSIKTTNSYCVVLWCDQGSATINAPDRVVQVMAGDVVLAPHGAFVTGHGVVLPMAFPDFDGGEHTRRLHMGTAWSKRMIFEFSRSLLGETRPSECIAALFDDRARPPRVPEPQAARKVAQKLIAYPADQTPLLEFAQLHNISSRTLQRQFVASTGFTFSEWRAALRVSVAADLLAHDFRIGQVSQMVGFSATSSLTRAFKRHTGDTPSSFTSPRMHAVCEQQPPMIPATTTFARASDDIALWIYSGTATVTTPGYCRFMGAGETVTIPSGTSTRLDVSAGSVALPVPLAAAHDDLTLSDVLAASVNPLAAVELQRLSAQERADVEQVLVPSV
What is the function of this protein?
Under iron limitation, represses the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and katA (catalase) genes.
What are the official names of this protein?
HTH-type transcriptional regulator RipA, Repressor of iron proteins A, RIPA.
Protein: RD41_PHYIT
Sequence: MRSIFYFALAFAALTCSNASAALPNPDETRLLSDTFTKRSLRVAGQEAARGEEIVRVTAQSTNKIFKRPAEKDMSKLIAAAKKALLEKKMAKLSKVIKKPAK
What is the function of this protein?
Effector that enhances P. infestans colonization of host plant leaves (PubMed:25936676).  During the early stages of P. infestans infection, interacts with and stabilizes host potato K-homology (KH) RNA-binding protein KRBP1, leading to its accumulation (PubMed:25936676).
What are the official names of this protein?
RxLR effector protein PexRD41.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus, host nucleolus. Host nucleus. Note=Forms a ring around the nucleolus. Nuclear localization is necessary to promote P.infestans colonization.
Protein: OTCC_BORAF
Sequence: MYNLRNRSFLNLLDFTSKDIKYLLDLSIDLKKSKYAGIEVQKLKGKNIVIIFEKDSTRTRCAFEIAAYDQGANITYLGPKGNQIGVKESMKDTARVLGRMYDAIGFRGFSQETVECLANYSNVPVYNGLTDISHPTQILADLMTIKEHKGSLKGIKIVFCGDGRGNIANSLLKGCAIMGLDFRIFAPKELFPDSNLTLKAKSLALKSGGKITITDSKEEAVKCADVVYTDVWVSMGEESNWEDRINLLKLYQVNKELMCMAKDDAIFMHCLPAFHDLSTVVGRDIFDKYGLDGIEVTEEIFESKNSVVFDVAENRVHAIKAVMVSTLG
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT1B1_RABIT
Sequence: MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQVPQIQKTEIAFRPSDPKSYEEYVVNIVRFLEKYKDSAQKDDMVFEDCGDVPSEPKERGEFNNERGQRKVCRFKLNWLGNCSGIDDETYGYKDGKPCIIIKLNRVLGFKPKPPKNDSLEFSPGTKYNPNVLPVQCTGKRDEDKEKVGSMEYFGMGDYAGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKIEVKS
What is the function of this protein?
Involved in cell adhesion and establishing epithelial cell polarity.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein. Cell membrane, sarcolemma. Note=Colocalizes with OBSCN at the intercalated disk and sarcolemma in cardiomyocytes. Localizes in long striations at the level of Z and M lines.
Protein: RPC3_BPP22
Sequence: MIIAIAGSARMGVSQLHESLLDRITRKLRAGWKRLADILNQPGVPSHDYCAC
What is the function of this protein?
Presence of the CIII protein in the cell results in the stabilization of the CII transcriptional activator (a very unstable protein), CII activates CI, the gene for repressor, and thus promotes the establishment of lysogeny.
What are the official names of this protein?
Regulatory protein C3, CIII.
What is the protein family that this protein belongs to?
Belongs to the lambda phage CIII protein family.
Protein: TPIS_FRAP2
Sequence: MQKLIMGNWKMNGSSASIKELCKGISEVNYNSEKVAVAVFPSSVYVKEVLAQLPKEIGVGLQNITFYDNGAYTGELSAEMLHDVGCNYLLIGHSERRSLFGETDQDVFKKLNKIIDTSVVPVVCIGESLEDRQGGRLEKVLTTQLSLILENLSIEQLARVIIAYEPVWAIGTGVVASLEQVQETHQFIRSLVAKVDENLAKNMKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKASEFNEIINQANKICTE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AN34C_HUMAN
Sequence: MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHSPPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLKRARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTNSIDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGPSGPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSRESLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSSSKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT
What are the official names of this protein?
Ankyrin repeat domain-containing protein 34C.
What is the protein family that this protein belongs to?
Belongs to the ANKRD34 family.
Protein: BPC4_ARATH
Sequence: MENGGQYDNARFKPDYFKGAQSMWNMIPQHQIKEQHNALVMNKKIMSILAERDAAVHERNQAVSAKKEAVAARDEALQQRDKALSERDKALIERDNAYAALQHHENSLNFALSGGKCVDGDDCFGIGEPHKLEVFPLSTIPPEVTNTKVVNKRKKENKQGLSKVKKVGEDLNRRVPAPGKKSRTDWDSQDVGLNLVTFDETTMPVPMCSCTGSTRQCYKWGNGGWQSSCCTTTLSQYPLPQMPNKRHSRMGGRKMSGNVFSRLLSRLSAEGYDLSCPVDLKDYWARHGTNRYITIK
What is the function of this protein?
Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
What are the official names of this protein?
Protein BASIC PENTACYSTEINE4, AtBPC4.
What is the protein family that this protein belongs to?
Belongs to the BBR/BPC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AB6A_ARATH
Sequence: MAKPVAASFLTQANALFKKNLTYQKRNIWSNVRLIVIPLYLCVVLVCIQAVFDSLVNNSVDNQCGCRCADDDKNGDGKCEIKSCGLQYSSQNQAVFCAFPNPPPLLPLLHIPPSVNRDSCQRTGSCPVTILVTGNNQSLGTTLSENLLSTSFTVNSSSDLFLRNLAYNVLSTTSETDYTNYRDPGIYSDLPIFNIQPQCTPATILSLSFRQPPLEFHKEVRCVQGLNLWRNNSLEVNDEIFKGFRKENHEEIINEVAAAYDLLNTDRNKFNVTIWYYTTYKGDLQDWRVKYVRVPRSVNMVSNAYLQFLRGPGTKILFDFVKEMPKQETRLRMDMASLIGPIFFTWVILLLFPVILTSLVYEKQQRLRIIMKMHGLGDAPYWMISYAYFLAISTLYIVCLMIFGSAIGLKFFRFNDYTIQFMFYFLYINLQISIAFLVSSAFSKAVTASVVAYIYVFGSGLLGAFLFQFLIESLSFPRRWIFVMELYPGFSLYRGLYEFSQYAFQRNLNGRDGMKWKDFRGSAMDEVFTIIIVEWVVALVATYYIDRVSSSSKDTFAFLKNPFKLSPTPQMLSFQKERSDVSVEMEKLDVIQEKETVKQLIFERSKNHGIVCDNLKKVYQGRDGNPPKLAVCGLSLAVPSGECFGMLGPNGAGKTSFINMMTGLVKPSSGSAFVQGLDICKDMDKVYISMGVCPQHDLLWETLTGKEHLLFYGRLKNLKGHDLNQAVEESLKSVNLFHGGVADIPAGKYSGGMKRRLSVAISLIGSPKVVYMDEPSTGLDPASRINLWTVIKRAKKHAAIILTTHSMEEAEFLCDRLGIFVDGRLQCIGNPKELKGRYGGSYVLTITTSPEHEKDVETLVQEVSSNARKIYHIAGTQKFEFPKEEVRISEVFQAVENAKRNFTVFAWGFADTTLEDVFIKVAKTGL
What are the official names of this protein?
ABC transporter A family member 6, ABC transporter ABCA.6, AtABCA6, Putative ABC2 homolog 5.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family. CPR flippase (TC 3.A.1.211) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SVS4_MOUSE
Sequence: MNSTSLFLFSLLLLLVTGAIGKKTKEKFLQSEETVRESFSMGSRGHMSRSSEPEVFVRPQDSIGDEASEEMSSSSSSRRRSKIISSSSDGSNMEGESSYSKRKKSRFSQDALE
What are the official names of this protein?
Seminal vesicle secretory protein 4, Seminal vesicle protein 2, Seminal vesicle secretory protein IV, SVS IV.
What is the protein family that this protein belongs to?
Belongs to the SVP2/SVP5/SVP6 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: GP45_BPSP1
Sequence: MMMDKQVEEVKKHYPIVEDWSVIVARKEDDCMTVTDAVPFILAGYKNVSYEMDDIVVLCSEPIGLTWEDVRFLKNHEGSVSFEEIGYEDKAMVYHVDLG
What are the official names of this protein?
Putative gene 45 protein.
Protein: MIAB_CLOPE
Sequence: MTLENNMDKKLFCISTYGCQMNEEDSEKLSGMLKSQGYERTENKEEASIIIFNTCCVRENAENKVFGNLGQLKQLKKKNPNLVIAICGCMMQQVGMADKVLKTFPYVDIIFGTHNAHKFPEYLHRVLQEGVQVKEILNKEEGIVEGLPIDRKSDVKAFVTIMYGCNNFCTYCIVPYVRGRERSRKSEDIIKEIEELVSQGYKEITLLGQNVNSYGKGLEEDIDFAGLLRKVNEVKGLERVRFMTSHPKDLSDDVIMAIKECDKLCEQVHLPVQSGSSRILKEMNRHYDREYYLDLVKKIKSEIPDVTLTTDIIIGFPGETEEDFLDTLSLCEEVGYDSAFTFIYSRRNHTPADKMENQIPDDIKHDRFNRLVEAINKKVVIKNKEYEGKVVEVLVEGPSKNDETKLTGRTRNGKLVNFAGDEKLVGELVNLKIVRAQPFSLIGEIVE
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_VIBVY
Sequence: MMSINPIVLLFALLCTLLSPFSIGQSTIIHEQKSLYQDIVVFEHQDFRCLSFTAKKGERVQTCEYQDPQDKRIYFPYVRMTLAGLLFNPKPERILIIGLGGGSVPSALAELYPESHMDIVEIDPVVSQIAERYFYFQPSHNTRVHTGDARVYIKRAGLKGQKYDFILLDAFNGEYIPEHLMTREFLMETKQLLSSSGVLVANTFSTSKLYDHESATYRSVFGEFYNFKIPQESGNRVILSMLIPLPNQQALQQQAEALTSALQPFAIEIENYPSLMTLEADWDEQARLLTDQFSPANLLK
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_HELPG
Sequence: MSAYIIETLIKILILVAVFSALGGFATYIERKVLAYFQRRLGPCYVGPFGLLQVAADGIKLFTKEDIIPQGANKFIFTLAPIIAMVSAFVSMAPIPFFPNFTLFGYEIKPLISDINIGFLFFLAVGAAGIYAPILAGLASNNKYSLIGSARATIQLLSFEVVSTLTILAPLMVVGSLSLVEINHYQSGGFLDWLVFKQPLAFVLFLIASYAELNRTPFDLLEHEAEIVAGYCTEYSGLKWGMFFLAEYAHLFAFSFVISIVFFGGFNAWGFIPGGLAILIKAGFFVFLSMWVRATYPHVRPDQLMDMCWKIMLPLALLNIVLTGIIILI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYG_LEPIC
Sequence: MEKKESLDSSLKEIVSVCKRRGFVYPGSEIYGGLSNTFDYGPYGVELLQNLKQLWWKYFVHLREDIVGLDSSILLNPKVWEASGHVSNFNDPLIDCKNCKTRIRADKFLEDQKGEGFATGLTLEKMNQVIKESNFACPNCGQRGTFTEARDFNLMFKTSHGASAEDSLDIYLRPETAQGIFLNFKNVVSTTRRKIPFGIAQIGKSFRNEIMARQFVFRTREFEQMEMEFFCEPGTQKEWFSHWVNYCMNWLTEQVGIKKENLRVREHEKEELSFYSEGTSDIEFKYNFGWGELWGIASRTDYDLNQHQKFSGEDLKYQDQVQNKKYVPFVVEPALGVNRLFLAVVTDAYEEEKLPDGETRTVLRFSPKIAPVKAAVFPLMKKDGLPEKSREIFADLSKLGNIEYDDGGAIGKRYRRQDEIGTPFCITVDYDTLKDNTVTVRERDSMSQERIAVNQLKNWLFERL
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRB11_LITCT
Sequence: MAQINPLPVPLGPWKITVYDQENFQGKRMEFTSSCTNIMECGFDNIRSLKVECGAWIGYEHTSFCGQQFVLERGEYPPWDAWSATNAYHIERLMSFRPICSANHKESKLVIFEKENFIGRQWELRDDYPSLQAMGWGNNEVGSMKVQCGAWVCYQYPGYRGYQYILESDHHGGEYKHWREWGSHAQTFQIQSIRRIQQ
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin A1-1.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: THOC1_MOUSE
Sequence: MSPTPALFSLPEARTRFTKSTREALNNKNIKPLLTAFSQLPGSENEKKCTLDQAFRGVLEEEIINHSACENVLAIISLAIGGVTESVCTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDDEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERASDTKPTRVVRKRAAPEDFLGKGPNKKILIGNEELTRLWNLCPDNMEACKSETREYMPTLEEFFEEAIEQADPENMVESEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPITGEQIESFANKLGEQWKILAPYLEIKDSDIRQIECDSEDMKMRAKQLLVAWQDQEGVHATTDNLISALNKSGLSDLAESLTNDTETNS
What is the function of this protein?
Participates in an apoptotic pathway which is characterized by activation of caspase-6, increases in the expression of BAK1 and BCL2L1 and activation of NF-kappa-B.  This pathway does not require p53/TP53, nor does the presence of p53/TP53 affect the efficiency of cell killing.  Activates a G2/M cell cycle checkpoint prior to the onset of apoptosis.  Apoptosis is inhibited by association with RB1 (By similarity).  Essential for early embryonic development.  Required for normal gene expression during postnatal testis development.
What are the official names of this protein?
THO complex subunit 1, Tho1, Nuclear matrix protein p84.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm. Nucleus matrix. Cytoplasm. Note=Can shuttle between the nucleus and cytoplasm. Nuclear localization is required for induction of apoptotic cell death. Translocates to the cytoplasm during the early phase of apoptosis execution (By similarity).
Protein: LADH_METM5
Sequence: MFIDGKWILREDIDVFDPYTLENIEKITALDREETKSAIEVAEKNKEIMKNLSPSKRYSILMKIAEQISLKKDLFAKTISIDVGKPIKQSKIEVDRTLTALKLSAFYAKELRGETINSENGLIFTKKEPLGVVGAITPFNFPLNLITHKIGPAIATGNSVVLHPSSKAPIVAIYLTKIIEHVLKQMDVPRGIFNLATGNGDIVGDEISKNDNINMVSFTGSVEVGESISKNAKMKKVALELGGNNPMIVLKDSDIKLAAKSAVKSKFLNAGQVCISVGQVLVEEEVLETFTKHVIEETKKLILGNPLDTKTDIGPLISPESALRIENLIKKSVNEGGEVLIGGNRQNSLISPAVINIDENNILSKIETFGPVLPILKVKDSEEAVSIANNSKYGLQAGVFTNDINKAMKIADSLEYGGIMINSSPTFRKDNMPFGGVKKSGLGREGIKYTVEEMCETKTIVIHNI
What is the function of this protein?
Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate.
What are the official names of this protein?
Lactaldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: NUOK_METS4
Sequence: MIGLSHYLTVAAILFTLGVLGIFINRKNVIVILMCVELILLAVNINLVAFSTHLGDIVGQVFALFVLTVAAAEAAIGLAILVVFFRNRGSIAVEDVNMMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OREX_RAT
Sequence: MNLPSTKVPWAAVTLLLLLLLPPALLSLGVDAQPLPDCCRQKTCSCRLYELLHGAGNHAAGILTLGKRRPGPPGLQGRLQRLLQANGNHAAGILTMGRRAGAELEPYPCPGRRCPTATATALAPRGGSRV
What is the function of this protein?
Binds to orexin receptor HCRTR2/OX2R only (PubMed:9491897).  Stimulates food intake (PubMed:9491897).  Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner (PubMed:9879756).
What are the official names of this protein?
Hypocretin neuropeptide precursor, Hypocretin, Hcrt, Orexin precursor, Prepro-orexin, Preprohypocretin.
What is the protein family that this protein belongs to?
Belongs to the orexin family.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum. Note=Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
Protein: MNMA_CAUSK
Sequence: MAAMDADIAPFDTARTDHGLMDRAVEQARAAVGLPVGTRIVAAMSGGVDSTVTAALLAKAGYDVVGVTLQLYDHGAAITKKGACCAGQDILDARMAAERIGIPHYVLDYESRFKEQVIEEFADAYLRGETPIPCVRCNQTVKFRDLLDVARDLGAEAMATGHYVQRSFAAGANRPQLRRAADPAKDQSYFLFATTAEQLDFLRFPLGGMDKPTVRLVAAELGLAIADKPDSQDICFVPEGKYTTVIDRIRPHGALPGDLVHMDGRVLGRHEGVTRYTIGQRRGLNIAVGDPLFVVKIDADKRQVIVGPREALLTQALSLKEGNWLGVEDSLEAAAAAGAPVLARVRSTREPVPGRLTLVPGPNGGEPRLVFDGLEEGVAPGQACVLYDPADPERVLGGGFIVATERAGL
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_CRYNB
Sequence: MPPSIPVPSIVTRAIPSLARAASTTTKSTPSKEHHVHSYSPEVLPLGYAVASTHASIKKKTGALDLGILVSTTDKPASAAACLTRNVFKAAPVTVTTQLLQSGGGRARGFIVNSGCANAVTGKKGLEDAWEMSNTVTSQLPPGQRGIGTLVMSTGVIGQPLPISSIISKIPELVRSLDDSPKSWLDLSKSFMTTDTFPKLRAKSFRLGERLVRIAGIDKGAGMIAPSMGPPQPPHATLLGVIATDAAISPPALQSALNYAVDRSFNNITVDGDMSTNDSIICLANGAAGKLETQGRETAEGMEEITEDGHPEEYKVFREELRSFAEELAQLVVRDGEGATKFVTIRVKNAPSYETAQAVAKSIANSSLFKTAMYGEDANWGRILCAVGYTPTAQAIIPNHVSVSFIPSANVSDPTPLRLLTNGEPEANIDEDRASVILAEEDLEVEVDLGDGHEEAKVWTCDFSHEYVTINGSYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RS8_ECO8A
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PYRC_SHESH
Sequence: MTQITLLTPDDWHLHFRDGDMLKETVPATARLFQRAIVMPNLLPPVTDAKMVIEYRERILAARPEGSDFEPLMTLFLTNDTTEQDIIDAKAAGVVAAKLYPAGATTNSDAAVKALDALFPIFEKMAEVGMLLLVHGEVTESHIDIFDREALFIERNLRRIVDAFPTLKVVFEHITTKEAADFVMSASDNVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRNIHQEALRAAIATGSSKFFLGTDSAPHEKHRKESACGCAGCYSAWSALELYAQVFDDLGIIDKLEGFASIHGPDFYGLPRNTSTVTLVKEKWTVPSEIILPNGNPIVPFFAGEEVSWKVKS
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.