PharMolix/UniProtQA huggingface dataset:
Protein: AEP2_YEAS8
Sequence: MWINRLVKHPSYSVLRFYTKRLCTVSVKSLREFGVLPNSTICHSVYPRRTYVMGRAVINDILIKKSYSTHTVCAIDRSKDENNGSAYDKFEAKGIPIDVHTLKRIISSSGMDESEFSKSISYLFAKTVDPEPKDVLSLEDLSFLLNKLYTQRFQIRRICRDINAKYSEFWFKLFSLYAEKVDAKRNQVNLRNTKLDACEIFDANLMIKNFIELGQLGKAQKILSFILDRNPDILLSPKNADISTIVHFLQLRCGALAPYWKIPDNSEQKQGFLRKMVRLGAKNTSIRLSSTYKAMDHQTLLKIADLALQEKKLLNSEDLLSTLIQSFGHLGQTQILERCIEHIWQISPQEFPSHVVIKHRGCYPSSKILVSILVSFYFNDHDLHRGLSILDSFIKHYPDVKLDALFWRRLFQLSHFAWTPANDKKATSVVRCWHLMKQWYASKRLRPSVDYETLRQLYDIMKKTGNFPLGIDVLRSFKPGIERTRAENAGKVNNIIIKYQKCIIKELVNRGRFSAVREFIDNYGFDRKMTKDLNIFCANRMFLRSKKMKNKIENKKEREKVRLDSFDDDEDDGMIIGSLW
What is the function of this protein?
Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.
What are the official names of this protein?
ATPase expression protein 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AEP2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DUT_NITEC
Sequence: MKQVDIKLFDPRLKDCFPGYATPGSAGLDLRACIDERTEIHPGETLLIPSGIAIHLANPGFAAVVLPRSGLGHKHGIVLGNLVGLIDSDYQGQILVSCWNRGQTTFALEPLERIAQLVIVPVIQASFNVVNDFQHSQRGERGFGSTGKC
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PURA_DEIDV
Sequence: MPGIAIVGAQWGDEGKGKITDFLAPEAEFVVRYQGGANAGHTVTAKGQTFKLNLLPSGVLHEGTVSVLGDGMVIDADKFMEERRNLIAGGLNPELRISDRAHLVLPHHKYVDGRKDFVGTTGRGIGPAYADRARRVGVRFGDLSDDTVLRERLERLLEAKPNSTRDAGWTSVDVAMESLAPIREALLPFVQDTGSQLRAAITEGRNVLFEGAQATLLDLNYGTYPFVTSSHPTVGGILVGAGVNHKAIHKVYGVAKAFNTRVGHGPFVTEVLGDAEILRLRGDGSKPWDEFGTTTGRARRVGWLDLHLLKYAVEVNGLDGLVINKMDILSGMDSIPVCVSYDAAGEPVYKHMKGWATTDGADSRASLPREAQAYLDLIEETVGCPVVIFSAGPAREQTYGSVSWT
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_TROWT
Sequence: MCLIDSVHARQILDSRGTPTVEVEVTLEDGSMGRSAVPSGASTGAFEAHELRDQDNNEYLGKGVTRAVRSVNSEIAPVLIGFDAFDQVGLDHRMIELDGTNNKSRLGANAILGVSLASASAAARAADLSLFRYLGGPSSRILPVPMMNIINGGAHADTGVDIQEFMILPVGARSFSESLRWGCEVYHSLKVQLRESGLSSGLGDEGGFAPALRSNRTALDLILSAIEKAGFSPGIDIVLALDIAASEFCKAPGHYRFEGKDITSDELISYYEGLLSSYPLVSIEDPLDQDDWEGYRTLTTHIGDRVQIVGDDLFVTNTSRLSRGIQSGVANSILVKVNQIGTLTETFDAVDMAAKGGYTAVLSHRSGETEDTTIADMAVATNCGQIKTGAPARGERIAKYNQLLRIEEKLGRSARYAGWLSYPRWQGK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: FOLD_CALS4
Sequence: MKRMIIDGKEISNRIKEEVKREIQEFGYKPRLAILMAGDDESSKVYANSKVKACESVGIEAKVYYFSEKEEDKFFDTLEKLNEDKDTHGIMIEMPLPKGFDVDKVYDTINPYKDVDCISNYNMGRLFAGKPLFVPCTPKAIIHILENTGVDLEGKHAVVIGRSNILGKPVAKLLLDKNCTVTVCHSKTKDLAYHTKQADVLVVAAGKMNLVRGDMVKEGVVLIDAGINVHEGKIYGDADFESIKDKASYVTPVPGGVGPVTTAMILKNTLEAFKYAVKSL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ATG9_DEBHA
Sequence: MSEYNQNSNNDTFLSRVFGLHSVYNQLQDEYQYYDPDVDYQQSFMNGGVLSSHVREEGNENTNNDNTNLLDSESDSDSSSSLSSPPSPIVSFTGKEHNQNEDSTKVHWDTTRPHYGQDNDITTSIPKDPPKKNMVNTAKNFINKLHPATDSLPMYNQPQQFRKPPPEGPSVQTVYQKKQHKSKRKYVIPPKERALYLWANITNMDEFLTDVYYYYRGNGMLNIVLTRLVDLLILAFILSFTVFLKWGINYDFFMSSSSDRASVTLKDLVIPNFISEMVPVSVKLLLLGFSGYIVLRLVQLYFDYNYKLKEIKNFYHYLIGIPNDDELMTISWIVIVERLMALKDYNSLTSTNTNLPAQFLSDLNSKVRLNAHDIANRIMRKENYIIALINKEVLDLSLSIPFLSNVNSFLSNKSVLTKTLDWNIKLCINNFIFNQHGQINSHVLKDFNRNQLSKELSARFKMAAIINLLLCPFIVIYFVLLYFFRYFNEYKSNPSSILGLRQYTPWAEWKLREFNELPHFFIKRLHLSIGPANIYINQFPRGFWVINLMNFVNFVSGAITAILVLMGLWFDNEEHNFWSFEITENKSSLFYISLFGTVWAITSSSLTSTNSNTSENLNSQTSSFFYDPEASLRYVSQFTHYLPSSWNGRLHTVQVKNEFCELFSMKIIIIINEILSLILTPFILWFKVSNSSGAIIDFFREYSIHVDGLGYVCYFAMFNFEQKDKNMMMSLNKSKKRKPRKSRANAKKKASSKSKSRSDEIELDNVNSNKADKSKLSDSETSSNSDDNDDTDINNDYYQDDKMIKSYMYFLETCGNDKAKQASKLTSNEQLSTKPSRIAKPDNSQSVVGDPTPSFLYQPLTSNSIDDSSYNINYNIDEQEEESSKGKRSGVLGMINQFYKHDRNR
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MURC_SHEAM
Sequence: MTQTEKYRQLRTMIPEMRRVRRIHFVGIGGAGMGGIAEVLVNEGYQVSGSDIADNAVTERLGSLGARIFIGHGADNVSGVDVVVVSTAIKHDNPEIAAAKEKRIPIVRRAEMLAELMRYRHGVAVAGTHGKTTTTSLIASIYGQAERDPTFVIGGLLNSAGTNARLGSSRYLIAEADESDASFLHLQPMVTVVTNIEADHMDTYGGDFEKLKSTFVDFMHNLPFYGVAVVCVDDPVVRELIPRIGRQVVTYGFSDDADVQALNFVQEGHSCRFTVRRKGKDDLSLKVNLPGQHNVLNSLAAIAVATEDDIEDEAIVKALAEFQGIGRRFQHLGKFATPNGEVMLVDDYGHHPSEVLATIKAARAGWPDKRLVMAYQPHRYTRTRDLYEDFVEVLSQVDKLVLLEVYAAGETPIPGADGRALCRSIRQRGQLEPIFVASPEQLTSVLPDVLADGDLLLCQGAGNIGALSRELAATELGFAKVENN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWP08_PHAVU
Sequence: KPDPEAVLIV
What are the official names of this protein?
46 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PURA_CORJK
Sequence: MAAIIVVGAQWGDEGKGKATDILGGKVDYVVKPNGGNNAGHTVVVGGEKYELKLLPAGVLSENATPIIGNGCVVNLEALFEEIDGLEARGANASRLRVSANAQLVAPYHVAIDRVAERFLGKRAIGTTGRGIGPTYADKVSRVGIRAQDLLDESILRQKIESALDQKNQILVKIYNRRAVDVDEVVEYFLSYADRLKPMLIDATTELNKALDAGKSVLMEGGQATMLDVDHGTYPFVTSSNPTTGGACVGTGIGPTRITASLGIIKAYTTRVGAGPFPTELFDKWGEFLQTTGGEVGVNTGRKRRCGWYDSVIARYASRVNGFTDYFLTKLDVLTGIGEIPICVAYDVDGVRHDEMPMTQTEFHHATPIYETMPAWDEDITDCKTFEELPEKAQDYVKRLEELSGCRISYIGVGPGRDQTIVINDVAEG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_LIMRD
Sequence: MANILKKWIESDRRELRRINKIANKVESYAKQMSELTDEQLQAKTDEFRERYKKGESLDHMLPEAFAVSREGAKRVLGLYPFHVQIMGGIVLHEGNIAEMRTGEGKTLTATMPVYLNAISGKGVHVITVNEYLSKRDATEMGQLYNWLGCSVGINNSEMSPDQKREAYKADIMYSTNSEIGFDYLRDNMAVYKEDQVQRGLNYALVDEVDSILIDEARTPLIISGPGTGTSKLYKQTDRFVKQLKKDVDYKIDLESKTVSLTDEGIKKAEKYFNLKNLYDPENTALTHHLDQALRANYIMLLDKDYVVQDGEVLIVDSFTGRVMEGRRFSDGLHQAIEAKEGVEIQEENKTMANITYQNLFRMYNKLAGMTGTAKTEQEEFREIYNMETITIPTNRPVQRKDEPDLLYPTLQSKFAAVVDRIKKLHAKGQPILVGTVAVETSEYLSQLLDKENIPHVVLNAKNHAKEAEIVKNAGQKGAVTIATNMAGRGTDIKLGPGVREIGGLAVIGTERHESRRIDNQLRGRSGRQGDPGLSQFYLSLEDDLMKRFGGDRIKAFLERMKVNDEDAVIKSRFLTHQVESAQKRVEGNNYDSRKNVLQYDDVMREQREIIYKERQQIITEDKSLKWVLMPMFRRTIQREVDQHTLGDKKDWDLQGIVDFAEEVLIKPDTITVKDLEGKSPQEMVDYLMTFAQGVYKEKQKQLYDPAQMLEFEKVVILRVVDSHWTDHIDIMDQFRQSVGLRGYGQLNPLVEYQTAGYHMFEQMIADIEYETTRLFMKSEIRQNVTR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: RL1_PSEAE
Sequence: MAKLTKRQKAIAEKVVAGKQYSFEEAAKLLAELSTIKFKESVDVAVNLGVDPRKSDQVVRGATVLPNGTGKSVRVAVFTQGPAAEAALAAGADKVGMDELAAEMKGGDLNYDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVRFRTDKNGIIHSSVGKVDFEPAKLQQNVEALLADLKRLKPSSSKGVYVKRVTLSTTMGPGLQIDLASLEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: DTD_NEIG2
Sequence: MRAVIQKTVGAKVDVVSEAGTETCGKIDGGFVVLLGVTHSDTEKDARYIADKIAHLRVFEDEAGKLNLSLKDVGGAVLLVSQFTLYADAASGRRPSFSQAAPAEQAQRLYLRTAELLRGHGIHVETGRFRTHMQVSLCNDGPVTILLDSFMTRISPKMKVVPD
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APC11_DICDI
Sequence: MKVTIKSIWNTVSAWHWDVNEECCGICRMAFDGCCVDCKIPGDDCPPVWGVCNHAFHMHCILKWLNANELQQCPMCRSEWRFKSDEK
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
What are the official names of this protein?
Anaphase-promoting complex subunit 11, APC11.
What is the protein family that this protein belongs to?
Belongs to the RING-box family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HCP_KLEP3
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIASLQGLSAWALKAREYGIIDHEVDSFAPRAFFSTLTNVNFDSPRIVGYARQAIALREALKAQCQNLDASAAVDNPVADLHLVSDDLGDLQRQAADYAPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNAIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFQVMSILDAGETTKYGHPTPTQVNVKATEGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLIGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVNHLEGEDFAPVITQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLVGGCDGARGERNYFTDFATSVPDDCLILTLACGKYRFNKLDFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFFTPDLLAVLNEKFGLRSVTTVEQDMQQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTSB_STRPA
Sequence: MITEFIDGLQQFHFLQNALITAIAIGIVAGAVGCFIILRGMSLMGDAISHAVLPGVALSFILGINFFIGAIVFGLLASILITYIKSNSIIKSDTAIGITFSSFLALGVILIGVAKSSTDLFHILFGNILAVQDQDMWMTIGVGVTVLLVICLLFRPLLLTSFDPVLAQSMGVRVKIYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANSLWSMMLLSSSLGALASILGLFIGYSLNIAVGSCIVLTSAVFFLISFFIAPKQRKNKHALSSH
What is the function of this protein?
Part of an ABC transporter complex involved in manganese import.
What are the official names of this protein?
Manganese import system permease protein ScaB, ORF1.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU4LC_NUPAD
Sequence: MMLEHVLVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNMNLVTFSDLFDSRQLKGDVFSIFVIAIAAAEAAIGPAIVSSIYRNRKSTRINQSNLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CARB_GIBFU
Sequence: MSDIKKSVIVIGAGVGGVSTAARLAKAGFKVTILEKNDFTGGRCSLIHNDGHRFDQGPSLLLLPRFFHEIFQDLGTSLTAEGVELLKCEPNYNIWFGDGSSFEMSTDLTKMKKAIEAVEGIDGFERYLGFLQESHRHYEVSVESVLRRNFPSILSLARPEVLFNLFNIHPLESIWTRASKYFWTERLRRVFTFGSMYMGMSPFDAPGTYSLLQYTELAEGILYPRGGFHKVVEALVNVGQRLGVEYRLSTGVKSISIDQATGKANGVVLSDGTHLPSDIVISNADLVYTYNNLLPKTSYADSLSKRETSCSSISFYWSASKIVPELNAHNIFLADEYQESFDSIFKEHLIPSEPSFYVNVPSRIDPSAAPEGKDSIVVLVPVGHLLSDSEGTHRGLSKSGNSGGLETSQDWDKMISLARDTVIATMRARIGVDLAPLIENEIINTPFTWQEKFNLDKGAILGLSHSIMNVLAFRPGTQHSKYKNLYFAGASTHPGTGVPVCIAGSKIVAEQILKDSGFKNNQIPWAQDTTKSPKGGLDKMSDSSLTLFQGFLGALVAILLAYYYLVIAAN
What is the function of this protein?
Phytoene desaturase; part of the car gene cluster that mediates the biosynthesis of neurosporaxanthin, a carboxylic apocarotenoid acting as an essential protective pigments and leading to orange pigmentation (PubMed:12172798, PubMed:10905351, PubMed:19645721).  Converts phytoene into lycopene via the intermediates phytofluene, zeta-carotene and neurosporene; and further desaturates gamma-carotene into torulene (PubMed:12172798, PubMed:10905351, PubMed:19645721).  Neurosporaxanthin is synthesized from geranyl-geranyl pyrophosphate (GGPP) through several enzymatic activities.  Phytoene synthase activity performed by the bifunctional enzyme carAR first produces phytoene from geranyl-geranyl pyrophosphate (GGPP).  The phytoene dehydrogenase carB then introduces 4 desaturations to lead to lycopene which is substrate of the carotene cyclase activity of carAR that leads to the production of gamma-carotene.  CarB then performs a 5th desaturation reaction to yield torulene.  Torulene is the substrate of the dioxidase carT that breaks the molecule, removing five carbon atoms to yield beta-apo-4'-carotenal, whereas the aldehyde dehydrogenase carD mediates the last step by converting beta-apo-4'-carotenal into neurosporaxanthin (Probable).
What are the official names of this protein?
Phytoene desaturase, Carotenoid biosynthesis cluster protein B, Phytoene desaturase (3,4-didehydrolycopene-forming).
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family.
Protein: RS18_BRABE
Sequence: MSLVIPEKFQHILRVMNTNIDGRRKIMFALTSIKGVGRRYSNIVCKKADIDLSKRAGELSDEEVERLITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVMANSLDNKLREDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVGVSKKK
What is the function of this protein?
Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
What are the official names of this protein?
40S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_MYCTA
Sequence: MTDGNQKPDGNSGEQVTVTDKRRIDPETGEVRHVPPGDMPGGTAAADAAHTEDKVAELTADLQRVQADFANYRKRALRDQQAAADRAKASVVSQLLGVLDDLERARKHGDLESGPLKSVADKLDSALTGLGLVAFGAEGEDFDPVLHEAVQHEGDGGQGSKPVIGTVMRQGYQLGEQVLRHALVGVVDTVVVDAAELESVDDGTAVADTAENDQADQGNSADTSGEQAESEPSGS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_GLOVI
Sequence: MRRKVLAGNWKMYKTRGEARAFLEAFVPLISPGAENREVILCGPFTCLDLLSAQAGPYAVGAQNVHWADHGAYTGEIAPQMLVELGVHYVIVGHSERREYFNETDSTVNRRLNNAQDHDLVPILCVGETESVRKDGITEAHIRSQLDRDLELVDMRRLIIAYEPIWAIGTGKTCEANEANRVCAMIRKHVNFEGVPILYGGSVKPENIDELMAQSDIDGVLVGGASLEAKSFARIVNFEV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFM2_MOUSE
Sequence: MSHNSQAFLSTNAGLPPSYETIKEEYGVTELGEPSNSAVVRTTVINMPREVSVPDHVVWSLFNTLFFNACCLGFVAYAYSVKSRDRKMVGDVVGAQAYASTAKCLNISSLIFSILMVIICIIIFSTTSVVVFQSFAQRTPHSGF
What is the function of this protein?
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol.  Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV) and West Nile virus (WNV).  Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry.  Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
What are the official names of this protein?
Interferon-induced transmembrane protein 2, Dispanin subfamily A member 2c, DSPA2c, Fragilis protein 3.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. Late endosome membrane; Single-pass type II membrane protein.
Protein: RPIA_BURP0
Sequence: MTQDELKRLVGEAAARYVTENVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVATTERLKSHGIKVFDLNEIESLQVYVDGADEIDGSGAMIKGGGGALTREKIVASVAETFVCIADASKRVAVLGQFPLPVEVVPMARTAIGRRLAALGGVPVLRVKQDGAPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTERGVETLRYAAH
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RS14_SYNP2
Sequence: MAKKSMIERDKKRARMVAKYAAKRAALKEAFNNAADPLEKLEIHRKIQNLPRNSSPTRMRNRCQITGRPRSYYRDFGLCRNVLRDWAHQGLLPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RL7_SHEPA
Sequence: MSITKDQILEALAAMSVMEVVELIEAMEEKFGVSAAAAVVSGGSDAAAAEEKTEFDVVLTSHGDNKVAVIKALRAATGLGLKEAKGMAESAPVAVKEAISKEEAEALKADLEAAGAAVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: NEMP2_HUMAN
Sequence: MGPRQGRWWLLLWLPPLATLPVRGEAAAAALSVRRCKALKEKDLIRTSESDCYCYNQNSQVEWKYIWSTMQVKITSPGLFRIVYIAERHNCQYPENILSFIKCVIHNFWIPKESNEITIIINPYRETVCFSVEPVKKIFNYMIHVNRNIMDFKLFLVFVAGVFLFFYARTLSQSPTFYYSSGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQLMEDLKWLWYENRIYVLGYVLIVGFFSFVVCYKHGPLADDRSRSLLMWMLRLLSLVLVYAGVAVPQFAYAAIILLMSSWSLHYPLRACSYMRWKMEQWFTSKELVVKYLTEDEYREQADAETNSALEELRRACRKPDFPSWLVVSRLHTPSKFADFVLGGSHLSPEEISLHEEQYGLGGAFLEEQLFNPSTA
What are the official names of this protein?
Nuclear envelope integral membrane protein 2.
What is the protein family that this protein belongs to?
Belongs to the NEMP family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein; Nucleoplasmic side.