PharMolix/UniProtQA huggingface dataset:
Protein: TLCD4_XENTR
Sequence: MDDSVFISYCVVTGSFLGFQLLFSIISPRTFTKYSSTYRQLSFGKQCEWDSRCVSTTHALVVGSGCLYILAYDEAVNADPIWGDPFWVKMNVAITCGYLVHDLLLLARFWKVMRDPYMVCHHLAVFYSYGYVLNRGVLPYFANFRLISELSTPFVNQRWFFDVIGKPRSSWPVLLNGLAMALVFFIVRIAVIPSYYSQVFATFGTEGYIRLGIGPQVAWIVSCVVLDILNVFWMYKIARGFYKVVKAKPDGKPRRNHAD
What are the official names of this protein?
TLC domain-containing protein 4, Transmembrane protein 56.
What is the protein family that this protein belongs to?
Belongs to the TLCD4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS21_HYDS0
Sequence: MATVIVGDSESFEKAMKRFKKVVEREGILSELKRREFYEKPSQKKKRKERAARKRLLKAMKKKRVAL
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: DNAE2_RHOBA
Sequence: MCSWRCAAARSHASANRCTPKERLGRQENRSAHCPGTIRSIRMEWSRWERQEFRCKRSFQRLGSSCEQFSPPMQNRRWEIERLPWRFSPVGKPFHFRDNVRAMRYVELHCRSNFSFLDGASHPDELVQRAAELGYEGLAITDRESIAGVVRGFSPAQELGLQYIVGTEVHPTDAPPMVLWPTDRAAYGRMCRMLSTGRMRCEKGRCELSFEDIAEHAQGILAGVIATDESRSIEDQHAHVNDSRQFLRGPFRDVFDDRGYLLASFHRGVDDAAKATWLRNLSLATDVPLLACGDVRYHSAERMALHDCVVAISQGKSVEQIQSDRLVNSQHHLRSLEEIAELYRDVPDAVARTIEVAQRCTFTLDQLKYEYPVELAPEGMTPIEHLKRLTWEGARGRWPNGVPEKVIETLRHEVTLIEDLQYEAYFLTVWDLVRFARSQEILCQGRGSAANSVVCYCLGITSVDPTHTDLLFERFISRERGEAPDIDVDFEHQRREEVLQYLYEKYGRDRAGMTAVVTCYRAKSAIREVGKALAISPDIIDAVAKLAGSYSRNPELPERCRDAGLDPDTPLGRRFLYLTETLIGFPRHLSQHVGGMVMTAGSLCELCVTENAAMPGRSVIQWNKDDLDDIGILKVDILALGMLSAIRRCFELVKDHHNRELSLSTIPPDDTPTYDMICAADTMGVFQIESRAQMSMLPRLKPRCYYDLVIEVAIVRPGPIQGNMVHPFLAARENPAAAKYPNDAIRKVLEKTLGVPIFQEQAMKLAVVAAGFTPGEADQLRRAMAAWRRPGVIDRFRTKLLEGMKANGLNGEFAENVFRQIRGFGEYGFPESHAASFALLVYASCYLKRHYPTAFCAALLDSQPMGFYAPAQLIRDAQQHGVQVLPVDINDSNIRSKLIPDLNRPHPKLRLGLQMVRGLPSAVAQKIIVARDANGPFANLHDLTTRAKLSRSNIATLADADALASIAQDRRAAVWQSLAQDDSGDSMPLLADLEPDCSVPEELVPMSPAEEVKNDYATTGLSLKAHPVSFWRDDLNALRCKRASDLPKLRDGVHVRVAGLVLMRQRPGTAKGITFVTMEDETGSMNLVLFAQVWKRFFKIARGSDAWIVDGKLENKKGVIHVIVGRVEDLSEKASGLKVPRRDFR
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANTF_SARPE
Sequence: MVKLFVIVILALIAVAFGQHGHGGQDQHGYGHGQQAVYGKGHEGHGVNNLGQDGHGQHGYAHGHSDQHGHGGQHGQHDGYKNRGY
What is the function of this protein?
This protein inhibits the growth of a variety of fungal species.  The antifungal activity of this protein is enhanced by the presence of sarcotoxin IA.
What are the official names of this protein?
Antifungal protein, AFP.
Protein: LPIN3_HUMAN
Sequence: MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVLRSREKVVDIELNGEPVDLHMKLGDSGEAFFVQELESDDEHVPPGLCTSPIPWGGLSGFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDSSPEELEAGAESELSLPEKLRPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPERVSRGKGSPKRSQHLGPSDIYLDDLPSLDSENAALYFPQSDSGLGARRWSEPSSQKSLRDPNPEHEPEPTLDTVDTIALSLCGGLADSRDISLEKFNQHSVSYQDLTKNPGLLDDPNLVVKINGKHYNWAVAAPMILSLQAFQKNLPKSTMDKLEREKMPRKGGRWWFSWRRRDFLAEERSAQKEKTAAKEQQGEKTEVLSSDDDAPDSPVILEIPSLPPSTPPSTPTYKKSLRLSSDQIRRLNLQEGANDVVFSVTTQYQGTCRCKATIYLWKWDDKVVISDIDGTITKSDALGHILPQLGKDWTHQGITSLYHKIQLNGYKFLYCSARAIGMADLTKGYLQWVSEGGCSLPKGPILLSPSSLFSALHREVIEKKPEVFKVACLSDIQQLFLPHGQPFYAAFGNRPNDVFAYRQVGLPESRIFTVNPRGELIQELIKNHKSTYERLGEVVELLFPPVARGPSTDLANPEYSNFCYWREPLPAVDLDTLD
What is the function of this protein?
Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis therefore regulates fatty acid metabolism.
What are the official names of this protein?
Phosphatidate phosphatase LPIN3, Lipin-3, Lipin-3-like.
What is the protein family that this protein belongs to?
Belongs to the lipin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAB1B_BOVIN
Sequence: MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGGERPNLKIDSTPVKQAGGGCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity).  Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum (By similarity).  Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.  Required to modulate the compacted morphology of the Golgi.  Promotes the recruitment of lipid phosphatase MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment (By similarity).
What are the official names of this protein?
Ras-related protein Rab-1B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor; Cytoplasmic side. Preautophagosomal structure membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, perinuclear region. Note=Targeted by REP1 to membranes of specific subcellular compartments including endoplasmic reticulum, Golgi apparatus, and intermediate vesicles between these two compartments. In the GDP-form, colocalizes with GDI in the cytoplasm (By similarity). Co-localizes with MTMR6 to the endoplasmic reticulum- Golgi intermediate compartment and to the peri-Golgi region (By similarity).
Protein: DNLI_THEON
Sequence: MGDMKYTELSDLYRRLEKTTLKTLKTKFVADFLKKTPDELLEVVPYLILGKVFPDWDERELGVGEKLLIKAVSMATGVQEREIENSVKDTGDLGESVALALKKKKQKSFFSQPLTIKRVYQTFIKIAEASGEGSQDRKLKYLANIFMDAQPEEGKYIARTVLGMMRTGVAEGILRDAIAEAFKVKAELVERAYMLTSDFGYVAKVAKLEGNDGLGKVHIQIGKPIRPMLAQNAASVKEALLEMGAEAAFEIKYDGARVQVHKDGDRVVIYSRRLENVTRSIPEVVDAIKASIKSEKAIVEGELVAVGEGGRPRPFQYVLRRFRRKYNIEEMIEKIPLELNLFDVLYVDGEPLIDTPFRERRAKLEEIVEEGEKLKLAQQLVTKKVEEAEEFYKKALELGHEGLMAKRLDSVYEPGNRGKKWLKIKPTMEDLDLVIIGAEWGEGRRAHLLGSFLVAAYDPHSGEFVPVGKVGSGFTDEDLVEFTKMLKPLIIGGEGKFVEIEPKVVIQVTYQEIQKSPKYRSGFALRFPRYVALREDKSPEEADTIERIAQLYEFQERFKAKK
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.  Can use both ATP and NAD(+), but NAD(+) may be a preferred nucleotide cofactor.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP/NAD(+)], TNA1_lig.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: CT173_HUMAN
Sequence: MLSGPHPSPTFRPNPCPWPCLHSLWMEISPTQLCFLSPGPSPQSPSCCFQGMNSGSELGKLWRKLFKGIPRLSVSHFDFYCGTCVLLGRPQIPQGSSLGNDIDQYPVVFRNASDQGSWMQLEMLLRKLSDLVWTSDALSDKILEDGLVP
What are the official names of this protein?
Uncharacterized protein C20orf173.
Protein: YGFB_ECO45
Sequence: MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDSSWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRADALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEEIIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH
What are the official names of this protein?
UPF0149 protein YgfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: PRD16_MOUSE
Sequence: MRSKARARKLAKSDGDVVNNMYEPDPDLLAGQSAEEETEDGILSPIPMGPPSPFPTSEDFTPKEGSPYEAPVYIPEDIPIPPDFELRESSIPGAGLGIWAKRKMEIGERFGPYVVTPRAALKEADFGWEMLTDTEVSSQESCIKKQISEDLGSEKFCVDANQAGSGSWLKYIRVACSCDDQNLAMCQINEQIYYKVIKDIEPGEELLVHVKEGAYSLGVMAPSLDEDPTFRCDECDELFQCRLDLRRHKKYACSSAGAQLYEGLGEELKPEGLGVGSDGQAHECKDCERMFPNKYSLEQHMIVHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGSIFTPGLPLTPSPMMDKTKPSPTLNHGGLGFSEYFPSRPHPGSLPFSAAPPAFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPLNHAQDAKLPSPLGNPALPLVSAVSNSSQGATAATGSEEKFDGRLEDAYAEKVKNRSPDMSDGSDFEDINTTTGTDLDTTTGTGSDLDSDLDSDRDKGKDKGKPVESKPEFGGASVPPGAMNSVAEVPAFYSQHSFFPPPEEQLLTASGAAGDSIKAIASIAEKYFGPGFMSMQEKKLGSLPYHSVFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPKEAKPALLAPKVPLIPSSGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKPGVSEGLPKVCPAQLPQQPSLHYAKPSPFFMDPIYRVEKRKVADPVGVLKEKYLRPSPLLFHPQMSAIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQTNLDRHLKKHEHEGAPVSQHSGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFIANSEMNQASTRMDKRPEIQDLDSNPPCPGSASAKPEDVEEEEEEELEEEDDDSLAGKSQEDTVSPTPEPQGVYEDEEDEEPPSLTMGFDHTRRCVEERGGGLLALEPTPTFGKGLDLRRAAEEAFEVKDVLNSTLDSEVLKQTLYRQAKNQAYAMMLSLSEDTPLHAPSQSSLDAWLNITGPSSESGAFNPINHL
What is the function of this protein?
Binds DNA and functions as a transcriptional regulator (PubMed:18483224).  Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro (PubMed:22939622).  Probably catalyzes the monomethylation of free histone H3 in the cytoplasm which is then transported to the nucleus and incorporated into nucleosomes where SUV39H methyltransferases use it as a substrate to catalyze histone H3 'Lys-9' trimethylation (PubMed:22939622).  Likely to be one of the primary histone methyltransferases along with MECOM/PRDM3 that direct cytoplasmic H3K9me1 methylation (PubMed:22939622).  Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism (PubMed:17618855, PubMed:18483224).  Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells (PubMed:18719582, PubMed:19641492).  Functions as a repressor of TGF-beta signaling.
What are the official names of this protein?
Histone-lysine N-methyltransferase PRDM16, PR domain zinc finger protein 16, PR domain-containing protein 16, Transcription factor MEL1, MDS1/EVI1-like gene 1.
What is the protein family that this protein belongs to?
Belongs to the PRDM16 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: C1TC_SCHPO
Sequence: MALLLEGTSLARKVREELREQISSIKSVDPYFNVSLKIIQVGGREDSNVYVRMKTRAANEAGISCEHVNFPEDITEYDLLLAIKGFNEDPTVHGIIVQLPLPAHINEQIITEAVAPEKDVDGFCETNLGKLTKREGQPLFTACTPKGIMCILKHYGINVQGKHAVVIGRSNIVGRPMSILLEKANATVTLCHSKTESIADIVRTADIVVAAIGIPHFVKADWLKKGVVAIDVGINSIPDATKKSGYRLTGDIDFENAKEVASAITPVPGSVGPMTVAMLLQNVVESAVRFRKMSRKRKPTLLPLKLQTPVPSDIEIARSQTPKNIGDLASEIGIAKSELEFYGSHKAKVNLEILQRLAHRRDGHYVVVTGITPTPFGEGKSTLTAGLVQALSNLDKLAIACVRQPSQGPTFGIKGGAAGGGYSQFIPMEEFNLHLTGDIHAITAATNLLAAAIDTRMFHENTQSDAALYKRLTLVKGNKREFAPVMFRRLKKLGIDKTNPEELTEEEQRKFARLDIEPSTISWNRTLDVNDRFLRKITIGENPTEKGFTRQTGFDLSVASECMSVLALATDLKDMRERLGRMVVASNKSGEPVTADDLGVGGALTVLLKDAIKPTLMQTLEGTPALVHAGPFANISIGASSILADRIALKLAGTEVDEDAKKEAGYVVTEAGFASDIGMEKFFNIKCRTSGLKPDAIVIVATVQALKLHGGGPPVGPGKPIPEVYKREDVDLVRKGCANLAKHISNARKYGLPVVVAINKFSSDSPNEISAIREEALAAGATDAVDSNHWAEGGKGALGVARALINACENVDSEFRLLYDVHEPIEKKIEIIAKEMYGADGIELSPLAKERLETFTKQGYNNLPICIAKTQYSLSHDPDLKGAPTNFTVPIRDMRLSAGAGFIYPLAAAISTIPGLPTKPAYYNIDIAENGDIVGLS
What are the official names of this protein?
C-1-tetrahydrofolate synthase, cytoplasmic, C1-THF synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_RHILO
Sequence: MAKIAKRVSKTREGIDPNKAYALGEALKLLKDRSSVKFDETVEVAMNLGVDPRHADQMVRGVVNLPNGTGRSVRVAVFARGDKAEEAKAAGADIVGAEDLVDIVQKGTIDFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTTDVAAAVKASKGGAVEFRVEKAGIVHAGVGKVSFDVKALEENIRAFADAVTKAKPAGAKGNYVKKVSVTSTMGPGLKLDVSTLAAS
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: HEMH_RHOPA
Sequence: MSVIVPIHGPAIAPAPAPERVGVLLVNLGTPDSCDTKGVRIYLREFLSDPRVIENQGLFWKLALNGIILNTRPARKAKDYQKIWNHEKNESPLKTITRAQAEKLSASLGDRGHLIVDWAMRYGNPSLRDRIEALVAKGCTRLLVVPLYPQYSAATSATVCDQAFRVLRELRAQPTLRVTPPYYRDSAYIDALATSIKSHLASLTFEPELIVASFHGMPQAYIDKGDPYQAQCVATVEALRERMGVADDKLLLTFQSRFGFDQWLQPYTDKTIEALARKGVRKLAVVMPGFSADCLETLEEIAQENAEIFMEHGGEEFTAIPCLNDSDAGVQVIRQLVLRELQGWL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_ACTP7
Sequence: MAKKPKVASNTIALNKRARHEYFIEEEIEAGLELQGWEVKSLRAGKANIGDSYVTFRNGEAFLFGATITPLNMASTHIVCDPTRTRKLLLNKRELDSLFGKVNRDGMTVVALSLYWKNAWAKVKVGVAKGKKLHDKREDIKDREWQVAKQRIMKNANRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: IHFB_SALTI
Sequence: MTKSELIERLATQQSHIPAKAVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: TNFA_DELLE
Sequence: MSTESMIRDVELAEEALSKTAGGSQGSGRCLCLSLFSFFLVAGGTTLFCLLHFGVIGPQREEFPTGYSIISPLAQTLRSSSKTSSNKPVAHVVANLSAQGQLRWLNTYANTLLANSVKLEDNQLVVPTDGLYLIYSQVLFRGQGCPSTHLFLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYQGGVFQLEKGDRLSAEINLPDYLDFAESGQVYFGIIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Protein: LAP1_AJEDR
Sequence: MKFPSFLSLGIAASTTALAALPDQKPIGDTIADVHLGKFLIELAPGDTRWVTEEEKWGLKRDGRKFFDITAEVEQNLFPRAFAKTAVTFPTGLHRTVEVMPLAAQLSKDNMFSHLTTFTSFHTRYYKSETGIQSATWLMKQIQKTISSSPASNARVEKFEHPWGQFSVIATVPGQSNKTVVIGAHQDSINMFLPSILAAPGADDDGSGTVTILEAFRVLLQSEAIAQGNATNTVEFHWYSAEEGGLLGSQAVFSKYKQDNKDIRAMLQQDMTGYSKGTLDAGELESVGVITDFVDEGLTEFIKKVVNGYCDIPFVLTECGYACSDHASASRFGYPSAFVIESKFEHSSQHIHTGQDTIETLDFNHMLQHAKMTLGLAYELAFADI
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SMC3_DICDI
Sequence: MFIKFIFIKGFRSYKDQGFTSITLHPGFNVVTGRNGAGKSNLFAAIRFLLGDLNVGNNSEDRLKLLHSYGGNTMQTGYVEIVFDNSDHRFPIDKTEFSLRRTFGTSKDEFSIGNNKLSKADVRNMFEAAGFSSSNPYYIVQQGKINTLALMKDSDRLDMLKEVAGATVYEERKRESVAIMIESESKSIKIEEFLKYIDERIKVLDKERKELQLYQTQIEMKKQFEAYIIHLEANESNDRILDLEKEKEKYLIHSSKESKKLERFTDELKKDESKFNKLLSEIKKIDNEKIMVEKLNEVFDKQKAQLVIQQKHFKKLLSKEQAKLEKLQKEQDLLSGSKEKLEKEIEIIKPKLEELIGQEDDIDNKLSSTERNLQELYVKQGMFQFKSKTERDKYLGDESSKLEDIVNQYEQQAQSLEEDVEDMKQIQQSKGKQFDNSMASKDKEAEIVKTAELRVHELKLEKDQIEQRVSSTFQSINEMKSNLTEHRNEWKKAERNLQTIMNRPLSEGLTRLNQIRQEGKIKGIHGPLVELFDIVEPEATLALEVVGGNGLFHVVVDTDDTASKILEILNTENIGRLSFIPLNRVRTKPPKFPILENDLVCPLIKVISFDPIYTEAMKLVFGKTLICKDEATAEQVRKSSHVDCITFEGDVFHSKGAVTGGYYSKKKLKLSSYQQIKHWRQQYQQLQTQLTEKESELEKLQASLLSIQKTIRTKEDEKNKILSNNDNSRVELDKIISERTMYIEILEKKQTILKKLKIDIQNCKDTIDGYQKQINTAFNTKLTEEESNLLLTLSESSIQLKEQKISISSDVMKLQSRKNQMTNQLNQNYGKRLMEIEGEIKSLNPENSKLQIELKQKEIDEINIEIDGVREKLESLVQSLNEKDAEIKPIKVSIDALKQQTSTIADQLVADGKKMESLLAQIQSFNKVRDAKQLRVLSKGDRFNFEELKKYNKDQSVEELNKINKSLASLRHVNQKANDQFNSFTNQYNSLEARRDELYESNASIQLLIKTLDNKKDEAIARTFSGVAKNFTQVFKELIPGGSAKLVMKRQMDEDEGEGEDPKEWADGETPKGLLTFTGIGIQVSFGEGHEPCSMRQLSGGQKTLVALALIFALQRTDPAPFYLLDEIDAALDHNYRVAVSKMIRKHSREIQFIATTFGPEFVMDANQNWIVVFNKGGSKLVPGSTEDALNVIKQLDNGSAFDYSYQGITEEEFNQDRPVLGVAENKHLVAFEFKRAKKRALKALAKAEEACAIMVQDEANQDSNADSSEKLKHDKKIFEKLHKEYLLRAAEFNQVKERFIRFGGIIKQQGDDELSQSSQPQDKEMENIEKEKDNNQQTSDTEMKDTDQSTTKQKSPPKRKSPSQDTSDIETSDDESKKKQTESNQEESDIDEETPSQRFEEALNYASQKLKQHGLQESEQSEQEEDDDDISSDSSD
What is the function of this protein?
Central component of cohesin, a complex which is required for the cohesion of sister chromatids after DNA replication.  The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped.  Involved in chromosome cohesion during the cell cycle and in DNA repair it also regulates DNA replication.  At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.  The cohesin complex may also play a role in spindle pole assembly during mitosis and in chromosomes movement (By similarity).
What are the official names of this protein?
Structural maintenance of chromosomes protein 3, SMC protein 3, SMC-3.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCNB1_BOVIN
Sequence: MALRITRNTKISAENKAKISMAGAKRVPVAAVATSKPGLRPRTALGDIGNKVSEQPQAKLPLKKEAKTLASGKVTAKKVPKPLEKAPVPVPEPQPEPEPEPEHVKEDKLSPEPILVDTPSPSPMETSGCAPAEEYLCQAFSDVILAVSDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVKPKYLMGREVTGNMRAILIDWLVQVQIKFRLLQETMYMTVSIIDRFMQDTYVPKKMLQLVGVTAMFVASKYEEMYPPEIGDFAFVTDNTYTKFQIRQMEMKILRALNFSLGRPLPLHFLRRASKIGEVDVELHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKVLDNGEWTPTLQHYLSYTEESLLVVMQHLAKNVVMVNRGLTKHMTIKNKYATSKHAKISTLAQLNSALVQDLAKAVAKV
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-B1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: RL17_SHIFL
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: NU3C_LEPVR
Sequence: MFLLYEYDIFWAFLIISSAIPVLAFLISGVLSPIRKGPEKLSSYESGIEPIGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSAFIEALIFVLILILGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DCUP_THET2
Sequence: MDLVNDLILRAARGEPTPRPPVWFMRQAGRYQKAYRKLRERYTLPEIVQNPEVCAEVTLLPVKALGVDAAILFADITTPLYGMGVDLSLVENKGPVIHNPVRDEKGVEALRPLVPEEAVPFVLETIRILKRELPVPLIGFAGAPFTLASYLVEGGPSRRFLRVKALMYGEEALWHRLMEKLTEAMARYLRAQAEAGADLLQVFDSWVGALSPADYRRYVKPHMERLFQSLRPAGVPVIHFGVGTMGLLEDMKEAGGDVLGLDHHTPLPWARALLGATPVQGNLDPAVLLAPKGVIRREVQRILKENGGKSGHIFNLGHGIVPETPEENVRYVVELIQEVAA
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METJ_PASMU
Sequence: MANWDGKYISPYAEHGKKSEQVKKITVSIPIKVLEILTNERTRRQIRNLRHATNSELLCEAFLHAFTGQPLPTDEDLLKERHDEIPEQAKQVMRELGIDPEKWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATE_SALTI
Sequence: MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGTAIKGFKKAMNDEDAGVKKDVDGSVQAEKLSHKE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatE shares overlapping functions with TatA.
What are the official names of this protein?
Probable Sec-independent protein translocase protein TatE.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family. TatE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.