PharMolix/UniProtQA huggingface dataset:
Protein: RUVC_METC4
Sequence: MTTDVRILGIDPGLRRTGWGLITARGSKLSYLACGVVTSDGDLPLALRLRELHEGLTRIVTTYTPDEVSVEETFVNKDAQATLKLGHARAVALLVPALAGLPVAEYAANLVKKTVAGNGHAEKVQIQAMVKFLLPKAEFKLADAADALAIAITHASHRGAIALDRRHAVAAGGGPGAARIAAALARLDR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: VM1AT_CROAT
Sequence: EDQQNLSQRYIELVVVADHRVFMKYNSDLNIIRKRVHELVNTINGFYRSLNIDVSLTDLEIWSDQDFITVDSSAKNTLNSFGEWREADLLRRKSHDHAQLLTAINFEGKIIGRAYTSSMCNPRKSVGIXKDHSPINLLVGVTMAHELGHNLGMNHDGEKCLRGASLCIMRPGLTPGRSYEFSDDSMGYYQSFLKQYNPQIXNK
What is the function of this protein?
Snake venom zinc metalloprotease that has Aalpha, Bbeta fibrin(ogen)olytic activities.  It cleaves the Aalpha chain of fibrinogen first followed by the Bbeta chain and shows no effect on the gamma chain.  Does not induce or inhibit platelet aggregation, and is unable to activate plasminogen.  Exhibits low lethality when tested on mice.  Intravenous administration results in thrombolysis within one hour followed by recanalization.  Fibrinogenolytic activity results in a 60% decrease in the rat's plasma fibrinogen level.  Histological examination of kidney, liver, heart and lung tissue shows no necrosis nor hemorrhage.
What are the official names of this protein?
Snake venom metalloproteinase atroxase, SVMP, Nonhemorrhagic metalloprotease atroxase.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CP24A_RAT
Sequence: MSCPIDKRRTLIAFLRRLRDLGQPPRSVTSKASASRAPKEVPLCPLMTDGETRNVTSLPGPTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLLEALYRTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKINEVLADFLERMDELCDERGRIPDLYSELNKWSFESICLVLYEKRFGLLQKETEEEALTFITAIKTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDNRLQRYSQQPGADFLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQAQRRLLQEVQSVLPDNQTPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYALPKGTVLTLNTQVLGSSEDNFEDSHKFRPERWLQKEKKINPFAHLPFGIGKRMCIGRRLAELQLHLALCWIIQKYDIVATDNEPVEMLHLGILVPSRELPIAFRPR
What is the function of this protein?
A cytochrome P450 monooxygenase with a key role in vitamin D catabolism and calcium homeostasis.  Via C24-oxidation pathway, catalyzes the inactivation of both the vitamin D precursor calcidiol (25-hydroxyvitamin D(3)) and the active hormone calcitriol (1-alpha,25-dihydroxyvitamin D(3)) (PubMed:2026586, PubMed:16617161, PubMed:10231362).  With initial hydroxylation at C-24 (via C24-oxidation pathway), performs a sequential 6-step oxidation of calcitriol leading to the formation of the biliary metabolite calcitroic acid (PubMed:10231362, PubMed:16617161).  Hydroxylates at C-24 or C-25 other vitamin D active metabolites, such as CYP11A1-derived secosteroids 20S-hydroxycholecalciferol and 20S,23-dihydroxycholecalciferol (PubMed:25727742).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via FDXR/adrenodoxin reductase and FDX1/adrenodoxin (PubMed:2026586).
What are the official names of this protein?
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TRM13_VANPO
Sequence: MQPESKKQRLQCEFYMEKKKRRCGMSRNLSSKYCSEHQILNENTKRIPCPLDPNHTVWESDLDSHLKKCNKLKLIHQHDNKPYFLKDCNAITTEDSNTTVITKDSLQNWIMKTIPVLKNFFKDDEKNYLSNVPLDIRKNHTMEDKRFPQLNENDNIGKKYHAIQQSSLIQNMIDRNILQFKENSLANFIEFGCGRAELSRYVNQVVIKNSEEKIYNPHFILIDRSTNRMKFDTKMKKDALEFNQNLNPPTITRIRIDIKDLKIDPLLQKDSKYIAISKHLCGVATDLTLRSLTYNPDDNDFLQGVCIAMCCRHVCNSNNYVNPDFVKSIIGNTNTEEQLPYDQFFHALTKIAAWATSGDRPTSSDENNTHFTNLPYTERQELGLMARRVIDQGRCDWLQQKLGESFKVELIRYVEPSISLENVALLAYRK
What is the function of this protein?
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
What are the official names of this protein?
tRNA:m(4)X modification enzyme TRM13, tRNA methylase 13.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase TRM13 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: STM_DANRE
Sequence: MLSRTVFVPLILAFVGVSISAPVSNNNGTDNDESAADQRHIFTVQFNVGTPAPADGDSVTTDGKDSAEKNEAPGDSSDTTEKPGTTDGKDSAEQHGVTTDGKDEAEQHGVTTDGQDSAEKRGEADGAPDKPDTQNGTDDTDSDQETDASHHKTGDSDENKDKPSAEDHTDGNHAGKDSTDSKESPDTTDKPEGPDSDSAPDGDSASAEKTDSDHSPDEDANKSSTEADKDDTSDKDSSQTDEKHDSDASDKDEKHEDKDEKSDEKDSSKDSEDKSQEKSDKSDDGSNSEADEQKESVESKDHDSDSQDSDSAEKKEKHDDKDQDSSDSADSKDSDEDKDKDHSEQKDSEDHEHKEKHTKDKEEHKDSDEGKDDEDKSKSDEHDKDESESKEASKSDESEQEEKKDDKSDSDNSSRDSHSDSDSDSHSDSDSDSHSDSHSDSDSDSHSDSDSDSDSDSDSDSDSDSDSNSRDKDEKKDKSSESRDEDSSDSDSKSNSESSETAEEDTNDDKDSSVEKDKTDSSDSASVEANDSDDEHDDDSKDATPSSEDHTAEKTDEDSHDVSDDDDDIDAHDDEAGVEHGTDEASKPHQEPDHHDDTTHGSDDGRKTSMPIS
What is the function of this protein?
Essential for the formation of otoliths in the inner ear of developing larvae and for the perception of gravity and acceleration.  May be one of the organic components of the ortholiths.
What are the official names of this protein?
Protein starmaker.
What are the subcellular locations of this protein?
Secreted. Note=Detected on otoliths and the apical surface of epithelial cells in the otic placode in larvae 24 hours after fertilization.
Protein: RS7_HUMAN
Sequence: MFSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:23636399).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399).  Required for rRNA maturation (PubMed:19061985).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
40S ribosomal protein S7, Small ribosomal subunit protein eS7.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS7 family.
Protein: SSUD_ENT38
Sequence: MSLNLFWFLPTHGDGHYLGTEEGARPVDYGYLQQIAQAADRIGFTGVLIPTGRSCEDAWLVAAAMIPVTQRLKFLVALRPSVVSPTVAARQAATLDRLSNGRALFNLVTGSDPTELAGDGVFLDHTERYEASAEFTRVWRRLLEGDTVTYEGKHIRVRDAKLYFPPVQQPRPPLYFGGSSDVAQDLAAEQVDLYLTWGEPPEQVKEKIEQVRAKAAAHGRKVRFGIRLHVIVRETNQEAWQAADRLISHLDDDTIAKAQAALAKTDSVGQHRMASLHNGKRENLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYADLGIDSFILSGYPHLEEAYNVGELLFPHLDVAIPEIPQPRPLQVQGEAVANEFIPRKTAQS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: Y034_HIS1I
Sequence: MNRSHQLLSVLAIIFYGVMVVGSMMQFLAYYELTSLPSVRQVSLMLVGICAVVCFYASIVYFVEISSRG
What are the official names of this protein?
Putative transmembrane protein ORF34.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: SECA_ALKOO
Sequence: MRKLFEKVFGTYSEREIKKLDKTVDQIEALEAAYSKLTDAELKDKTRQFKERLAKGETLDDILPEAFATIREGAWRTLGMKHYRVQLYGGMVLHQGRIAEMRTGEGKTLMATLPVYLNALSGKGVHVVTVNDYLAKRDQEWMSKVYNFLGLTVGVIVHGITNEDRRKAYHCDITYGTNNEFGFDYLRDNMVIHLHEMVQRPLNYAIVDEVDSILIDEARTPLIISGQGDKSTKMYFIVDQFVKTLKKEVDFEVDEKANSVTLTEEGVERAEKYFAVDNLSDMENTELAHHINQALKANNLMKLDKDYVVKDGEIIIVDDFTGRLMFGRRYSEGLHQAIEAKEGLEVQRESKTLATITFQNYFRMYDKLSGMTGTAKTEEDEFISIYNMDVVEIPTNKPVVRIDEPDSVYKSEKGKVLSIIKDIEEKHKKGQPVLVGTISIEKSEELAAALKKKGIPHEVLNAKQHEREAEIIAQAGRKGIVTIATNMAGRGTDILLGGNPEFLAKREMKRMGYGDEIISMVTSHAETDNEELISARGKYEELYKRFKAETDREHEEVKAVGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYISLEDDLMRLFGGERMLGIVDKMGLAEDEAIEHRLLTNSIENAQKKVEGRNFGIRKHVLQYDDVMNKQREVIYGERKKVLEGENMRDHIFSLMANIVDESIPMYTSEATSTPEIDTEGLRNHLSKIFLKADFGFINGQNKDVESLKSQIVAAAEKAYAVKEEEIGSERMREIERVILLQVIDTKWMDHIDAMDQLRQGIGLRAIGQVDPVRAYQLEGYDMFQEMINSIQEDTVRFLFSIEKEAVVERKQVAKPIEASHGDGDAKKAPVVKKEESGRNDLCPCGSGKKYKKCCGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: DAB1_RAT
Sequence: MSTETELQVAVKTSAKKDSRKKGQDRSEATLIKRFKGEGVRYKAKLIGIDEVSAARGDKLCQDSMMKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKTGALQHHHAVHEISYIAKDITDHRAFGYVCGKEGNHRFVAIKTAQAAEPVILDLRDLFQLIYELKQREELEKKAQKDKQCEQAVYQTILEEDVEDPVYQYIVFEAGHEPIRDPETEENIYQVPTSQKKEGVYDVPKSQPVSAVTQLELFGDMSTPPDITSPPTPATPGDAFLPAPSQTLPGSADVFGSMSFGTAAVPSGYVAMGAVLPSFWGQQPLVQQQIAMGAQPPVAQVIPGAQPIAWGQPGLFPATQQPWPTVAGQFPPAAFMPTQTVMPLPAAMFQGPLTPLATVPGTNDSARSSPQSDKPRQKMGKEMFKDFQMAQPPPVPSRKPDQPSLTCTSEAFSSYFNKVGVAQDTDDCDDFDISQLNLTPVTSTTPSTNSPPTPAPRQSSPSKSSASHVSDPTADDIFEEGFESPSKSEEQEAPDGSQASSTSDPFGEPSGEPSGDNISPQDGS
What is the function of this protein?
Adapter molecule functioning in neural development.  May regulate SIAH1 activity.
What are the official names of this protein?
Disabled homolog 1.
Protein: Y037_ABVP
Sequence: MTVEGLTILRSPTFLTIIVLLMIVFGIAIVALLTQYV
What are the official names of this protein?
Uncharacterized protein ORF37.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: MSRB5_ARATH
Sequence: MAASPLVVQKTEEEWRAVLSPEQFRILRQKGTEKPGTGEYDKFFEEGIFDCVGCKTPLYKSTTKFDSGCGWPAFFEGLPGAINRTPDPDGRRTEITCAACDGHLGHVFKGEGYGNPTDERHCVNSVSISFNPAKSSSII
What is the function of this protein?
Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins.  Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation.  MSRB family specifically reduces the MetSO R-enantiomer (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase B5, AtMSRB5, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CSN12_CRYNB
Sequence: MKYQQFVNSFTHPLQHEDHTPLLRLLSVHGKAAKGIADTVGAIDEKRLKNPGHTLPDLWDEIAVRHCACVYALYKTKDYTEAFNQQDKLLSLFYRWFVDQSSWVLPVLYMMLSDLRDLAEQADQTIHAETGKMPSLEICTRTVSKAFSLCATDRQFKGEESRRRGVYHTACLTIKCYFKVGKPNLCKNIIRAVVSDPKTPSVDTAPLPDQVTWHFYIGMLAFLNGEDKKADEELSWALKHCPADAKRNQELILTYLIPLRLLHGRFPSASLLSQHPRLELVFTPFINAIKNGDVEEYDRRLEWAQVRLVGMSVWLVVERAREGCLRSLFKKAWMASDKSTRVPIETFRLALKLHGVDVESDEVECMVANMIYRGYLKGYISHEKKMVVLGKTNPFPKMSTIAR
What are the official names of this protein?
Protein CSN12 homolog.
What is the protein family that this protein belongs to?
Belongs to the CSN12 family.
Protein: MURG_LEGPC
Sequence: MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPMDIPFHGVSSGKLRRYFSLKNLLDPFKIVLGIIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVTGTQISSQLLTGNPMKGLEVCRFISSKTCLLVMGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQFEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQAVQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CLPC_GUITH
Sequence: MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGIAAKVLKSMGVNLKDARVEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLALDLTKVRTQVIRLLGDTAEVSATNGQTKGKTPTLEEFGSNLTQKAAEGKLDPVIGRQKEIERVIQILGRRTKNNPILIGEPGVGKTAIAEGLAQRINNRDVPDILEDKRVVTLDIGLLVAGTKYRGEFEERLKKIIDEIRVANNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGEMQCIGATTLEEYRKHIEKDSALERRFQPVMVGEPSVEETIEILYGLRDRYEKHHKLVISDEALSAAAKFADQYIADRFLPDKAIDLIDEAGSRVRLMNSQLPPAARELDKELREILKQKDEAVRSQDFETAGQLRDREMEIKAQIAAIAHSKKGDEENTKEVSVVTEEDIAQIVAAWTGIPVNKMTRSESEKLLQMEETLHGRIIGQDEAVVAVSKAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKALASYFFGSEEAMVRLDMSEYMERHTVSKLIGSPPGYVGYNEGGQLTESVRRRPYTVVLFDEIEKGHPDVFNLLLQILEDGRLTDSKGRTVDFKNTLLILTSNVGSKVIEKGGGGLGFDLSEDQTESQYGRIKALVNEELKQYFRPEFLNRLDEIIVFRQLTKDEVGEIAEIMLKEVFTRISEKGIQLEVTARFKTHLINEGYNPIYGARPLRRAVMRLLEDTLSEEFLAEKIKEGDTAVVDVDDDGKVKVLLGEKLELVAN
What is the function of this protein?
May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpA homolog.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ANKZ1_RAT
Sequence: MLPAPRAAPVPASVSLLTLNGEAPLVRGLSLVSQAPGEALAWAPRTSCPGENTSSGRKVSPCSLDISDKLFCSACDQVFQNHQEQREHYKLDWHRFNLKQRLKNKPLLSASDFERQSSRGDLSSISGSEDSDSASEEDLLTLDEERAESEKPNRPPGFYPHRVLFRNAQGQFLYAYRCVLGPHQIPPEKAELLLQNLQNGGPRHYVVLMAAAGHFAGAIFQGREVVAHKTFHRYTVRAKRGTAQGLQDAQGRASRSAGANLRRYNEAMLYKDVRDLLAGPTWSKALGEAETILLHAPRSGRSLFFGGQGAPLQRSDFRLWDIPLTTRRPTFGELQRVLHKLTTLQVYDEDPREMVRFHSPETHCKPVREERKRDTEKEKTKVPSDANKALGQDEEPLKQGSESQEEDGSEVELELVELTLGTLDLREFEVLPKRRKKRKKKERSQKQQCGAHGPLLQQPQDEPFSQPTQVVATPLDTLVDEAKAPGQPELWDMLLAACRAGEVEVLKLQLATGPVDPGVMSLLSAPLGSGGFTLLHAAAAAGRGLVVRLLLEAGADPTVHDSRARPPYTVAADRSTRNEFRRFMEKNLDAYDYSKARVPGPLTQEMEARQATRKKEQKAARRQREQQQRKQREQEEQEQEERRRFAALSDREKRALAAERRLAAQLGAPSPPVPDSAVVNAGRCWSCGVSLQGLIPFHYLDFSFCSTRCLRDHRSQAGRPSS
What is the function of this protein?
Plays a role in the cellular response to hydrogen peroxide and in the maintenance of mitochondrial integrity under conditions of cellular stress (By similarity).  Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway (By similarity).
What are the official names of this protein?
Ankyrin repeat and zinc finger domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the ANKZF1/VMS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Translocates to the mitochondria upon exposure to hydrogen peroxide.
Protein: SARV_STAAS
Sequence: MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
What is the function of this protein?
Part of the pathway by which MgrA and SarA control autolysis.
What are the official names of this protein?
HTH-type transcriptional regulator SarV, Staphylococcal accessory regulator V.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_ECOL6
Sequence: MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLLGAISGLVFMVLQAWCGVPLAALFSVLVLALMTGGFHLDGLADTCDGVFSARSRDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQLLKRTLGGQTGDTLGAAIEFGELVFLLALL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPA_CHESB
Sequence: MFRGSITALVTPFRQDGSLDKKAFGALVEWQIAEGSSGLVPVGTTGESPTLTHDEHQEVIRLCVEAANKRVPVIAGAGSNSTREAISFAEHAEKVGADALLVVTPYYNKPNQRGLYEHFAAIARSTSLPIFIYNIPPRSVVDMLPETMARLAADFKNIVGVKDATAKLDRVSEQREACGPDFIQLSGEDATALGFNAHGGVGCISVTANVAPRLCAEFQAASLRGDGARAIELQDRLFPLHKALFLEPNPAGAKYALSRLGRLENVLRSPLVTVEASTAEKIDAAMKHAGLLN
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGB_PANTR
Sequence: MERPEPELIRQSWRAVSRSPLEHGTVLFARLFALEPDLLPLFQYNCRQFSSPEDCLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLASLGRKHRAVGVKLSSFSTVGESLLYMLEKCLGPAFTPATRAAWSQLYGAVVQAMSRGWDGE
What is the function of this protein?
Involved in oxygen transport in the brain.  Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom.  Not capable of penetrating cell membranes (By similarity).
What are the official names of this protein?
Neuroglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YQFD_SCHPO
Sequence: MDIRESRSQSPELSQSEDAVGPCPFLISVYHQFQTKNHVLDIFEDVIPSIQVYGWLTMTLYELGVLIADQLLLNNEETRHSEWSLQIRTIFYDKYKDRPIARDLGTVCLHNPKLFQGNKLLKRTGIKCGDKIDVTIKEDKIRIKK
What are the official names of this protein?
Uncharacterized protein C126.13c.
What is the protein family that this protein belongs to?
Belongs to the SAP18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SSRP_CHLPM
Sequence: MAKKQQTKTYTQAIQNRKARFEFEILDTVVAGIELLGSEVKSVRLGKASLNESFAIIHHGEVWLENMQITPYEFNHLDSLEPKRSRKLLLHKAEIAKLQSQISEKGLALIPLKAFFNPKGVLKLELAVAKGKKLFDKRETIKNRDNERQLQQIKKQY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RR7_CUSRE
Sequence: MSRRGTAEKKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAVKKIQQKTETNPLSVLRQAIRGVTPDITVKARRVGGSTHQVPVEIGSTQGKALAVRWLLAASRKRPGRDMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid.
Protein: DAPA_SHESM
Sequence: MINGSIVALITPMNSDGSVDFASLERLVEFHIDQGTDAIVAVGTTGESATLPMNEHVTVVAQTVKFAAGRIPVIGGNGANATSEAIELTKSLSKVGVAAMLGVTPYYNKPTPKGLVAHYKAVAASTDIPQILYNVPGRTAVDMKPETVAELVGVSNIIGVKEATGDVSRVKRLRELCGNDFMLYSGDDATAREFLLLGGNGVISVANNIVPKAFKAMCDAALAGNAELAASIDEPLRGLYTTLFCEANPIPVKWAAHRMGLIECGHIRLPLTELSEQCHGLLLDAMTRAQIEVK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.