PharMolix/UniProtQA huggingface dataset:
Protein: PK2L1_HUMAN
Sequence: MNAVGSPEGQELQKLGSGAWDNPAYSGPPSPHGTLRVCTISSTGPLQPQPKKPEDEPQETAYRTQVSSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAVGSKLKMLERKGWLAPSPGVKEQAIWKHPQPAPAVTPDPWGVQGGQESEVPYKREEEALEERRLSRGEIPTLQRS
What is the function of this protein?
Pore-forming subunit of a heterotetrameric, non-selective cation channel that is permeable to Ca(2+) (PubMed:10517637, PubMed:11959145, PubMed:25820328, PubMed:27754867, PubMed:29425510, PubMed:23212381, PubMed:30004384).  Pore-forming subunit of a calcium-permeant ion channel formed by PKD1L2 and PKD1L1 in primary cilia, where it controls cilium calcium concentration, but does not affect cytoplasmic calcium concentration (PubMed:24336289).  The channel formed by PKD1L2 and PKD1L1 in primary cilia regulates sonic hedgehog/SHH signaling and GLI2 transcription (PubMed:24336289).  Pore-forming subunit of a channel formed by PKD1L2 and PKD1L3 that contributes to sour taste perception in gustatory cells (PubMed:19812697).  The heteromeric channel formed by PKD1L2 and PKD1L3 is activated by low pH, but opens only when the extracellular pH rises again (PubMed:23212381).  May play a role in the perception of carbonation taste (By similarity).  May play a role in the sensory perception of water, via a mechanism that activates the channel in response to dilution of salivary bicarbonate and changes in salivary pH (By similarity).
What are the official names of this protein?
Polycystic kidney disease 2-like 1 protein, Polycystin-2 homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1.
What is the protein family that this protein belongs to?
Belongs to the polycystin family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle. Note=Interaction with PKD1 or PKD1L3 is required for localization to the cell membrane.
Protein: HPTS_STAA8
Sequence: MTAYKPYRHQLRRSLFASTIFPVFLVIIIGLVSFYAIYIWIEHRTIHQHVDESQSSLHHTEKQIQTFITQHNNSFQELDLTNHHDVTATKRELLKLIHQQPATLYYELSGPNQFITNNYEHLNTKNMYLFSTHQLKFKNSTYMLKIYMANTPRLSEIKKDNRQFALIVDQYDNILYANDDRFTIGEKYRPQQFGFMNESVKLNHADHRLIIYKDIHENIEDGITLLIVMAVVLVLLVIFGFISADNMAKRQTKDIETIIQKIYYAKNRHLGTYTPLKNNSELEEINNYIYDLFESNEQLIHSIEHTERRLRDIQLKEIERQFQPHFLFNTMQTIQYLITLSPKLAQTVVQQLSQMLRYSLRTNSHTVELNEELNYIEQYVAIQNIRFDDMIKLHIESSEEARHQTIGKMMLQPLIENAIKHGRDTESLDITIRLTLARQNLHVLVCDNGIGMSSSRLQYVRQSLNNDVFDTKHLGLNHLHNKAMIQYGSHARLHIFSKRNQGTLICYKIPLSRGNVDV
What is the function of this protein?
Member of the two-component regulatory system HptS/HptR that regulates genes involved in hexose phosphate transport system in response to changes in extracellular phosphate sources (PubMed:25644013).  May act as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to the conserved aspartic acid residue in the regulatory domain of HptS.  In turn, HptS antagonizes CcpA-dependent transcription of a subset of CcpA-regulated genes involved in antibiotic susceptibility (PubMed:30540769).
What are the official names of this protein?
Sensor protein kinase HptS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RID1_SCHPO
Sequence: MNSLRSVKRLLGARSLSSDGLSESVNSSDREDSLSFQTPSTPSEDEMPQCFEDLIKPQVLSSEASKSLLSLNEGIKMEIVSSLQQKDQKKRNKLIAWMRKKPCYEQPDDFISYIVNTKIDSIDESIIHKLALLLRNEQVIWVEKFIHNGGFGVVFCTIDKISRLEWREELHDSILEQLLLCVKAMCTVQRGLECLSQSTYNVERLISLLLSKKQPCDFVVREVLVQIVHSFYKAHLDKEEGAMQVFSLFSIKDDKDEEVEFLKNVRVDRPFRRWIIELEDVSRNVFWVWNHDSNVIDLEKQYNQVYEAPLGFIGGIETEATSYVAAHIHLINELLEGLPLEKRQRKRLELQLSGLERIMGLRFRKSSQKFHKKLHEALREWIVAAKIDDWPYKLVQTGST
What are the official names of this protein?
GTPase-binding protein rid1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at the cell tip and the barrier septum.
Protein: TUNAR_HUMAN
Sequence: MVITSENDEDRGGQEKESKEESVLAMLGIIGTILNLIVIIFVYIYTTL
What is the function of this protein?
In neurons, plays a role in the regulation of intracellular Ca(2+), possibly by acting as an activator of ATP2A2/SERCA2, thus increasing the efficiency with which Ca(2+) is removed from the cytoplasm (By similarity).  Inhibits differentiation of embryonic stem cells into neurons and inhibits neurite outgrowth, likely as a result of its role in intracellular Ca(2+) regulation (By similarity).  In pancreatic beta cells, lowers Ca(2+) levels in the endoplasmic reticulum and enhances glucose-stimulated insulin secretion (PubMed:34513312).
What are the official names of this protein?
Protein TUNAR, pTUNAR, Beta cell and neural cell-regulin, BNLN, TCL1 upstream neural differentiation-associated RNA.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Extracellular vesicle membrane; Single-pass membrane protein.
Protein: ACYP_SALTI
Sequence: MSNVCIIAWVYGRVQGVGFRYTTQHEAQRLGLTGYAKNMDDGSVEVVACGDAAQVEKLIKWLKEGGPRSARVDKILTEPHSPRETLTGFSIRY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: TRMD_CITBB
Sequence: MKFDILTLFPAMFEGPLTESILKRASDKGLIEVALHNIRDWAFDKHATADDAPYGGGAGMVMKVEPIAGAIEAVKAKNPNSKVILTTPCGRPFNHQFAEELSREEGVVIICGRYEGVDERVRTLFVDDEISLGDFVLTGGEIAAMVIVDAVSRLVPGVLGSDESAQYDSFADGLLEYPQYTRPPEFRGEKVPDILLSGNHAEIAKWRRKEQMRRTLASRPELLDGIEWSKSDKKLFVEVEKANQEKVAR
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCU21_RANGE
Sequence: GFVDFLKKVAGTIANVVT
What is the function of this protein?
Shows antibacterial activity against B. cereus, L. innocua, M. luteus, S. aureus, S. epidermidis and S. uberis.
What are the official names of this protein?
Maculatin-2.1.
What are the subcellular locations of this protein?
Secreted.
Protein: ANMK_SHISS
Sequence: MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: SLB3_MACLB
Sequence: MGRFIFVSFGLLVVFLSLSGTGAALNCASGWSGYDQHCYKVFDKPKSWADAEKFCKKQTSGGHLVSFHSSEETDFVVKLVSQTLESQILWMGLSKVWNQCDWGWSNGAKLKYKAWAEESYCVYFSSTKKGWRSRACRLLGHFVCKSPA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec B3/B5, C-type lectin B3/B5.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXJ_SYNS9
Sequence: MASLGVNIDHIANIREARRTVEPDPVPMAMLAELGGADGITVHLREDRRHIQDRDVELLRQTVRSRLNLEMAATAEMVAIALRVKPDMVTLVPEHRQEVTTEGGLDVVAQLSELTGMVSQLQTSGIPVSLFVDPVASQLRGCTDSGARWVELHTGRYAEGSWNDQPHELARLTEGTATARAMGLRVNAGHGLTYQNVEPVAAIPGMEELNIGHTIVARAVVVGLQQAVREMKALIQNPRRDPLFGQALG
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_RHIEC
Sequence: MSITAERKAALIKEYATAEGDTGSPEVQVAILTERINNLTEHFKDHKKDNHSRRGLLTMVSSRRSLLDYLKKKDEGRYSKLINSLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: UVRC_HISS2
Sequence: MFDAKNFLANVTHQPGVYRMFDEKGQVIYVGKAKDLKKRLSSYFRTNLNSKKTSALVSHIHSIETTITASETEALLLEHNYIKAFQPRYNVLLRDDKSYPYILLTKERHPRITSHRGSKKVQGEYFGPYPHAGAVRETLSLLQKLFPIRQCENSVYNNRSRPCLQYQIGRCSGPCIDGLVSDEEYQQQVDFARLFLQGKDQQVLEHLIKKMEQASMQLNFEQAAYFRDQIQAIRAVIEKQFVSNERLDDMDILAIAYQLGIACVQVLFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRIIPSTIIVDHVLNEKHELEVLLTEQAGRKVNIQDNVKGNKSKFLHLAQMNAQAALVTQLKQANLIQERYQALQELLSLTTIKRMECFDISHTMGEQTIASCVVFDTEGPLKSDYRRFNISGITAGDDYAAMEQALLKRYDRPLENEKIPDIIFIDGGKGQLNRALQVFAQLNVSWDKNKPLLIGVAKGVDRKAGLETLIISKQNKEVNLLPDSLALHLIQHIRDESHYHAIGGHRKKRQQAFTQSGLEAIKGVGAKRRQALLKYLGGMQGVKNATLAEISSVPGISAALAERIYETLRSE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTH_SERP5
Sequence: MSLVSQARSLGKYFLLLDNLLVVLGFFVVFPLISIRFVDQLGWAAVVVGAALGLRQLIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMAMADQPWLLWFSCALSALGGTLFDPPRTALVIKLTRPHERGRFYSLLMMQDSAGAVIGALIGSWLLQYDFHFVCWVGAGIFVLAAGWNAWLLPAYRISTVRTPMKEGMMRVLRDRRFLTYVLTLTGYYMLSVQVMLMLPIVVNEIAGSPTAVKWMYAIEAALSLSLLYPLARWSEKRFRLEQRLMAGLLLMTLSLMPVGLATSLQGVFTLICCFYLGSIIAEPARETLSASLADPRARGSYMGFSRLGLALGGALGYTGGGWMYDTGHSMNMPELPWILLGIVGFITLFALYWQFNPRSSAPAVAPGG
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ALR2_RHILO
Sequence: MNDAVNPTAAKTVTGWPVSEAAAGAILTIDLGAIRENYRRLKALLGGVHCAGVVKANGYGLGAAKVAAALTREGCDIFFVALLAEGIALRKAVGTGPDIYVLNGLPPGSEPEAVAAGLCAVINSGAQLKAWRAAVHDAGRRLPAAIQVDSGMSRLGMAPAEVEALAGDSSAFDGIDIKYVMSHLACADEPRHPANEQQRLAFERLRAMLPRAPASLANSSGIFLGPSYHHDLARPGAALYGINPTPGEPNPMLPVVWLQAKVAQTRRIEKGAGIGYGHSYHADGPLSLATISFGYADGWLRRSASAAWFEGVRLPFLGRVSMDSIILDISALPPGRLREGDLVELLGPSQSVDDAAGHAGTIGYEILASLGPRFHRHYVGG
What is the function of this protein?
Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA.
What are the official names of this protein?
Alanine racemase, catabolic.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: EXGB_ASPOR
Sequence: MKVTRLAVLNTLATLTVAWLPTTDKTITSSNGTDLFKASHGKIRGVNLGSQFVFEPWIATKAWSELGCEGQESEFDCVMKLGQDAANKAFAKHWDSWITKEDIKEIRSYGLNTIRIPVGYWMNEDLIYHDSEYFPHGGFAYLEKLCGWASDAGLYIIIDLHGAPGAQVAKNAFTGQFADTPGFYVDFQYQRALEFLEWMTIKVHTLHNFRNVGMLEVVNEPVQNPQVTTTLRSNYYPNAFHSIRKVEGALSIDRKDYLHIQMMDGAWGAGDPHEHLTDDYYAAYDNHRYLKWDPRVEVSKDSYIKTSCNDNVATNWPAIIGEWSLGVPDNVQETADWKPYSNLDFYQKWFAAQVQNYEQHQGWIFWTWKTQLDEYRWSYRDGVKAGVIPTDLNAVFREDVCKGRSS
What is the function of this protein?
Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall.  Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides (By similarity).
What are the official names of this protein?
Probable glucan endo-1,6-beta-glucosidase B, Beta-1,6-glucanase B, Endo-1,6-beta-D-glucanase B, Endo-1,6-beta-glucanase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2020_THEFY
Sequence: MATSRGDDLLPEIVVVTGMSGAGRSTAARALEDLDWFVVDNLPPALLPTMIDLAARTRGAVPQIAAVVDVRSMAFTEDLLSTVEDLRSRGIGARVVFLEASDETLVRRFESVRRPHPLQGDGRLTDGISRERELLRSIRGEADLVVDTSQLNVHQLKAKMVGFFGKARETRLRANVVSFGYKHGLPVDADLVLDCRFLPNPHWVPELRPLTGQDEPVRDYVLAQRGAKEMLDSYTEVLRLLVSGYQREGKHYMTLAVGCTGGKHRSVAMSEQLAARLRDEGVEVNIIHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Tfu_2020.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CR23_RANSP
Sequence: GLVSSIGKALGGLLADVVKSKGQPA
What is the function of this protein?
Acts as a male sex pheromone that attracts females (PubMed:10519546, PubMed:10601876).  Has no antimicrobial activity (PubMed:10519546, PubMed:10601876).  Strongly inhibits the formation of NO by neuronal nitric oxide synthase (nNOS) at micromolar concentrations (PubMed:11784303).  Acts by a non-competitive mechanism, probably by binding to calcium/calmodulin and as a consequence blocking calmodulin attachment to nNOS (By similarity).
What are the official names of this protein?
Splendipherin.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Caerin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LACC_CLOPE
Sequence: MILTITMNPSIDISYPLDVLNLDSVNRVTKVTKTAGGKGLNVTRVLKQLDADVLASGLLGGFFGDFIKNDLNINGIKHSFSDISGETRNCIAILHEGNQTEILESGPNISEKEANNFLRHFELLVDKANIISISGSLPLGISKDFYVKMLSICNKKDKRVVLDCSGEELRQVLKNDSKPFAIKPNIDELSDLLGVKVKDSIEDLKLILNTPMFNGIEWIVISMGAKGSFAKHNDKFYRVIIPKIQVVNPVGSGDSTIAGLTKGLNDGETDENVLKIANTLGMLNAQEHITGYVNMDNYKNLFEKIKVVEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: COTS_BACSU
Sequence: MYQKEHEEQIVSEILSYYPFHIDHVALKSNKSGRKIWEVETDHGPKLLKEAQMKPERMLFITQAHAHLQEKGLPIAPIHQTKNGGSCLGTDQVSYSLYDKVTGKEMIYYDAEQMKKVMSFAGHFHHASKGYVCTDESKKRSRLGKWHKLYRWKLQELEGNMQIAASYPDDVFSQTFLKHADKMLARGKEALRALDDSEYETWTKETLEHGGFCFQDFTLARLTEIEGEPFLKELHSITYDLPSRDLRILLNKVMVKLSVWDTDFMVALLAAYDAVYPLTEKQYEVLWIDLAFPHLFCAIGHKYYLKQKKTWSDEKYNWALQNMISVEESKDSFLDKLPELYKKIKAYREAN
What is the function of this protein?
Seems to be required for the assembly of the CotSA protein in spores.
What are the official names of this protein?
Spore coat protein S, Coat protein 40 kDa component 2, COT40-2.
What is the protein family that this protein belongs to?
Belongs to the CotS family.
What are the subcellular locations of this protein?
Spore coat.
Protein: DAPB_PROMA
Sequence: MEKIPVLVAGALGKMGSEVIKAIYKSNDCELVAAIDNANEMEGVDIGTALGMDQMDVAVTADLEGSLCVASQSVRNSSGNAVLIDFTHPNVVYEHSRASIAYGVHPVIGTTGLSIVQLEELREFANKASIGAAIIPNFSVGMVLLQQAAAAAASFYDYAELTESHHNQKADAPSGTCIKTAEIIEEIGKSFNKTTIKEQESIKGSRGGLRESGLRLHSVRLPGIVAQQQVLFGSPGETYLLSHNTIDRSAYMPGVLHTIRKVRHLKSLVYGLEKIL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_STAEQ
Sequence: MAKVAKKYAKALFDVALDTNQLDVVYEDLETISHSSFDFIKQLKAIDSNPSLTANQREEFVERVYNEANPYVVNTLKVLADNRHISIVENVFKSFQNLYNKYYKQDFAIIESTYELSEDEISRIVELIKKQTELSNVIVNTKINQDLIGGFRVKVGTTVMDGSVRNDLVQLQRKFERAN
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FDHE_SALPC
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKHWQKLLHSLIAELKPEMSGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_RHOP5
Sequence: MALREIIIVPDKQLRLTSKPVETVSPEVRKLADDMFETMYDAPGIGLAAIQIAEPVRLITMDLVRKEGNGKTEPRAFINPEIIGASTETRVYEEGCLSIPEYYAEVERPAQVRIRYTDLDGHVHEEDADGLFATCIQHEIDHLNGTLFIDHISRLKRALVMRKFEKAAKRGYKFVPAKTA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PLSY_LEPBL
Sequence: MNFAIFAFLSFISGSIPFGYWIALRFGKMDIRKFGSKNIGATNVGRSIGWKFGFPVLVLDVAKGIFPVYLSGIYIPEGGVPFQLACGVLAVLGHMFSPFLGFKGGKGVATTLGVFLVLTPIACFGAIFVFLVTIKYFKFVSIGSIFASLTLPLVYAFSSILLLHEEVSYWILGTMVFISIGIILTHRENIFRILNRSELFAVKNEDEERNGDSERNRR
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIM_LEUCK
Sequence: MKLSTLNETTPLVFNYANYVTPQFVANAVNVIGGSPIMAREVAEFSDLVAVSDAVVVNTGTWRRAELLETVKLIQIANQTQTVVVLDPVAVGIPSRSVPVQELLTNSKVDIIRGNAAEIAWFAGIDFASHGIDAVGSGNIEQIAQLAANKTGAIIAMSGPSDVISDGKTTRVLPVNVPLLASNVGTGDALSAIIGAFNGDEISLDNTVRAMAMMKLAGLTASHQVTTPGYFANQVLDELYLLSESKLETFIAKEVKKYE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: GUAC_SALG2
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQTWSGVPIIAANMDTVGTFEMAQALAGFDILTAVHKHYTVEEWATFINTASADVLKHVMVSTGTSDADFEKTVQILALNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTMPGDVAKAFGGGADFVMLGGMLAGHEESGGSVVEENGEKFMLFYGMSSESAMNRHVGGVAKYRAAEGKTVKLPLRGPVGNTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNSL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: RS8_SYNJB
Sequence: MAHTNDTIADMLTRIRNATMARHESVAVPATRMTRSIARVLHEEGFVSEWKEEGEGIQARVVLRLKYKGKGRNCRPIINGLKRVSRPGLRVYRNHKELPRVLGGIGIAIISTSNGIMTDREARKQGIGGEVLCLVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GDF8_COLLI
Sequence: MQKLAVYVYIYLCMLISVHPLALDDGSQPTENSEKDGLCNACTWRQNTKSSRIEAIKIQILSKLRLEQAPNISRDLIKQPLPKAPPLQELIDLYDVQRDDSSNGSLEDDDYHATTETIITMPTESDFLVQMEGKPKCCFFKFSSKIQYNKVVKAQLWIYLRQVQKPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKAFDENGRDLAVTFPGPGEDGLNPFLEVRVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS
What is the function of this protein?
Acts specifically as a negative regulator of skeletal muscle growth.
What are the official names of this protein?
Growth/differentiation factor 8, GDF-8, Myostatin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDUS8_HUMAN
Sequence: MRCLTTPMLLRALAQAARAGPPGGRSLHSSAVAATYKYVNMQDPEMDMKSVTDRAARTLLWTELFRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:22499348).  Essential for the catalytic activity and assembly of complex I (PubMed:22499348).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial, Complex I-23kD, CI-23kD, NADH-ubiquinone oxidoreductase 23 kDa subunit, TYKY subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.