PharMolix/UniProtQA huggingface dataset:
Protein: BETA_STAEQ
Sequence: MRRKRDSYDYVIIGGGSAGSVLGARLSEDKDKNVLVLEAGRSDYFWDLFIQMPAALMFPSGNRFYDWEYQTDEEPHMGRRVDHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMDTWDFAHCLPYFKKLETTYGAAPYDKVRGHDGPIKLKRGPATNPLFKSFFNAGVEAGYHKTADVNGYRQEGFGPFDSQVHHGRRMSASRAYLRPALRRRNLDVETRAFVTKLIFDENNSKKVTGVTFKKNGKEHTVHANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRMHLPGVGENFEDHLEVYIQHKCKQPVSLQPSLDVKRMPFIGLQWIFARKGAAASNHFEGGGFVRSNDDVDYPNLMFHFLPIAVRYDGQKAPVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIVFNYLSTKEDEREWIEAIRVARNILKQKAMDPFNGGEISPGPQVQTDEEILDWVRKDGETALHPSCSAKMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYVDYYKHGIDDEKAGAMEDDPFYQY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: THIG_BACAA
Sequence: MLNIGPFSFHSRLLLGTGKFPDFDVQQKAIDVSEAEVLTFAVRRMDIFDAKQPNLLEKLDVKKYKLLPNTAGAKNAEEAVRIAKLAKASGLCDMIKVEVIGDDRTLLPDPVETLRASEMLLEEGFIVLPYTSDDVVLARKLQELGVHAIMPGASPIGSGLGIVNPLNLSFIIEQATVPVIVDAGIGSPADAAFAMELGADGVLLNTAVSGAKDPIKMAQAMKLSIEAGRLGFEAGRIARKRCATASSPLEGMSVVE
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXD01_LYCSI
Sequence: MKILFVLISILYAVYCFSSEEDVDSAYLANELEPVEDINSEQYAALEPKEEQERSCADMGQDCKDDCDCCLNIATCNCWFGRYFCSCTFGDYQTCLRKKGKCKRNRPQSCPRSNLNRKKG
What are the official names of this protein?
U13-lycotoxin-Ls1a, Toxin-like structure LSTX-L1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 05 (agouti) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATC_GEOTN
Sequence: MSRISIEQVKHVADLARLAMTDEEAELFTKQLDAIITFAEQLNELDTENVPPTSHVLDMRNVMREDEPEPGLPREEVLKNAPDQQDGQFRVPAILE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: HBB_CARCR
Sequence: THWTAEERHYITSMWDKINVAEIGGESLARMLIVYPWTQKFFSDFGNLTSSSAIMHNVKIQEHGKKVLNSFGSAVKNMDHIKETFADLSKLHCETLHVDPENFKLLGSILIIVLAMHFGKEPTPTWQAAWQKLVSAVAHALTLQYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SYT_ACISJ
Sequence: MIHITLPDGSQREFAGPVTVAEVAASIGSGLAKAALAGKIGDKVVDTSYQITQDSPLSIVTAKDADGLEVIRHSTAHLLAYAVKELFPDAQVTIGPVIENGFYYDFSYKRPFTPEDLAAIEKRMAELAAKDEPVVRRVLPRDEAVAYFKGLGEHYKAEIIASIPTNEDVSLYREGGFEDLCRGPHVPSTGKLKFFKLMKVAGAYWRGDHRNEMLQRIYGTAWATKEELQEYLHMLEEAEKRDHRKLGRELDLFHIDEHSPGTVFWHPKGWTLWQEVEQYMRRVYRDNGYQEVKGPQILDKTLWEKTGHWDKYRDNMFTTESEKRDYALKPMNCPGHILIFKQGIKSYRDLPLRYGEFGQCHRNEPTGGLHGIMRVRGFTQDDGHIFCTEDHILAECTAYTALLQKVYKDFGFHNIIYKVATRPEARIGSDESWDKAEHALMESLRASGCEFEIAPGDGAFYGPKIEYTLKDAIGRQWQCGTMQVDFSMPERLDAEYVGEDGGRHRPVMLHRAIVGSLERFIGILIEEHAGALPVWLAPVQVAVLNITDAQQDYCREIAAKLQKALPNQGLRVVTDLRNEKITYKIREHSLQKLPYILVAGDKEKAAGAVAVRARGNKDLGVMSLDAFVDLIAQDIASKV
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_PROM3
Sequence: MSSKLRLGVAGPVGSGKTALVEAICRRLRDQLQLAVVTNDIYTQEDAEFLTRVGALEPERIRGVETGGCPHTAIREDCSINRAAVEDLERNFPDLDVVLVESGGDNLAASFSPELVDLCIYVIDVAAGDKIPRKGGPGITRSDLLVINKIDLADHVGADLEVMKRDATRMRGERPWCFTNLHSGDGLESVLQFLLQQLPNRPE
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMPS5_MYCTO
Sequence: MIGTLKRAWIPLLILVVVAIAGFTVQRIRTFFGSEGILVTPKVFADDPEPFDPKVVEYEVSGSGSYVNINYLDLDAKPQRIDGAALPWSLTLKTTAPSAAPNILAQGDGTSITCRITVDGEVKDERTATGVDALTYCFVKSA
What is the function of this protein?
Part of an export system, which is required for biosynthesis and secretion of siderophores.
What are the official names of this protein?
Siderophore export accessory protein MmpS5.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RNPA_STAA8
Sequence: MLLEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: YBEY_HAEDU
Sequence: MNPIIDLQIASENSQGLPSAQQFSDWVKHALTYEAQTSNIPLTELTIRIVDEAESHHLNLTYRGKDKPTNVLSFPFEVPEGIELPLLGDLIICRQIVEKEALEQKISLDAHWAHLTIHGTLHLLGYDHIDEHEAEQMEGLESDIMQQLGFQDPYLAEK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP_YERPN
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLVAVLQGLSAWALQARELGIIDSQIDSFAPRAFFSTLTNVNFDSDRIVEYAKDAILLRHSLAVRCRLLDSTITVDHPLAELQLVADDIPSLLQQSQQFALNNDKADVGDDIHGLRMLCLYGLKGAAAYMEHAHVLGQSDEQIYAEYHAYMAWLGTQPRDVDTLLNNAMGIGKMNFNVMAILDQGETQAYGDPQPTSVNVRPVAGKAILISGHDLKDLHMLLEQTQGTGINIYTHGEMLPAHGYPELKRYPHLVGNYGSGWQNQQTEFAKFPGPILMTSNCIIDPNVGNYGDRIWTRSIVGWPGVNHLDGDNFAPVIEQALGMAGFPYSELEHLITVGFGRQTLLNAADTVIDLVASKKLRHVFLVGGCDGSRTERSYFTDFARSVPQDCIIMTLACGKYRFNKLDFGTLEGLPRLLDVGQCNDAYAAIMLAVKLSEKLGCTVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIYTGPTAPGFLTDNLMAILYEKFGMQPITTVEQDMQAILGH
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_CLONN
Sequence: MLNSYDLIRRPVITEKSMAAMADRQYTFIVDIRADKTQIKKAVEKVFGVKVEEVRTARFDGKVKRVGVHVGKRSDYKKAMVKLTEDSKTIEFFEGM
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y3961_DICDI
Sequence: MKIFQIQCSSFKESRWQKSKCDNCLKFHIDINNNSKTSNTDTDFDANTNINSNINSNINSNININNSGNNNKNSNNIEITENIDNKAKIINKHIKTITNSKPIPIPIPTPTPISIKEKEKEKEKEKEKEKEKEKEKEKEMKSTINLRSEDTTSNKSTIVFTECLEYKGHQWRPNICVTCFSPKNKHKNVLPETSTPLISQSSQTSTITPSSSSTSTSTSSISTHKTANNKTVITYISSTTTTTTTSSSSSSPPSSSIAGITNPTSRSSSPILKSVPPSAYSNVVIPINNINNSNSNSSSGGGNNNNKSISTPSSPIISRPITNKINNNNNNNQPQLHYNQPQSSSVSTTSSPIIRPVLRRQFQSFPSNPKISKAILEQCNIINNNSNSNNSNNKDPVILCKYTIESQPKSNISVLKPTLVEFINQPDSKDDESSVKSPPLPVESQPIFNSKQSATMDGITTHKSVSITISTSTSPSSTTTTTSTTTSIIAEEPSSPILPTASPSSSSSSIITTATASTIPMSPSLPSIPFHEFETMESSTTTTLLSENNGGGGGSSCNDNSRRNSLNILPLRLKSFSFSAPQSDSMIEQPEDDPFFDFEDLSDDDDSNDNDDEELKEINGEKIIQQNDLTPTTTITSTTTILQSPTLEKTLSTTTTTTIPSPSTNSRSICNTLMDSTDSINNTNTNTNTNTNTNTNTNTNTNTNTNTNANINNKVSTTTTTTTTKRRSLKMDQFKEKEDEWDQGVDLTSFLKRKPTLQRDFSYCNNKVMEISSVKEEAKRLHGGTGYIHQFAFEAFKDILEAKQTQINRAFCSQKIDAPDCEMLINEINTAKKLLEDLLELNSNSSGSGNNSNDNSGSSSPSSSKTNTLNQQSICIKSEI
What are the official names of this protein?
Uncharacterized protein DDB_G0281025.
Protein: RS20_MYCUA
Sequence: MANIKSQQKRNRTNERARLRNKSVKSSLRTAVRSFRDAAHSGDKEKAAELLVSTNRKLDKAASKGVIHKNQAANKKSALARALNKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MIG15_CAEEL
Sequence: MSSSGLDEIDLNSLRDPAGIFELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKEQPHEQTIRHSIKEHIDRNRRVKKDDADYEYSGSEDDEPSPNNRGPSMGIRDDSESSSMIPMDNTLRKGFQKLQESSRGFAEPGAQQLRRLPQQPAPAPFQYQQSRYVEPRRESSEVKLRAVSSRGAADGPRHSPASRPRPVSHHQRSPQQSHPAAPHLADLANYEKRRRSEREERRERERQAHHAMPIARVSASVPAPQQSRKMSEPLLITHVKPEDLDVLASELSKMGGHHNGRSREESMSPPPPAPPPREASISSITDTIDVGELDNGADAEWDDLKDIMMNGEGTLRGPNKPLPPTPTDGENTLVSDVRRNGNGNSGHGAYKGKKIPEIRPGIISLDDDDSDSDNEEGNEPLMFKPINASSSRGALPDLLPKSPQLRRQINDQTRQMSDDRADESASLFGSFYQPNGFQNSDSRSSIQHSFSNRDREKSFVGYFGGGAGAGGGTVNRPGRPQDINQVQVNVTPNSNGTPAENDAPEIRKYKKKFSGEILCAALWGVNLLIGTDSGLMLLDRSGQGKVYPLISRRRFDQMTVLEGQNILATISGRKRRIRVYYLSWLRQKILRTEGAGSANTTEKRNGWVNVGDLQGAIHFKIVRYERIKFLVVGLESSIEIYAWAPKPYHKFMSFKSFGSLSHVPLIVDLTVEDNARLKVLYGSTGGFHAIDLDSAAVYDIYTPAQSGQTTTPHCIVVLPNSNGMQLLLCYDNEGVYVNTYGRMTKNVVLQWGEMPSSVAYISTGQIMGWGNKAIEIRSVDTGHLDGVFMHKKAQKLKFLCERNDKVFFSSAKGGGSCQIYFMTLNKPGLTNW
What is the function of this protein?
Involved in cell migration and signal transduction (PubMed:11967148, PubMed:22732572).  Important in several developmental processes including epidermal development, Q neuroblast migrations and muscle arm targeting.  Required with ina-1/pat-3 to stabilize the commissural axons growth cone along a precise direction and are required for the cell to respond appropriately when signaling in the growth cone must change (PubMed:11967148).  During gonad morphogenesis, involved in distal tip cell (DTC) migration from the dorsal side of the hermaphrodite body to the midbody to allow for formation of gonad arms (PubMed:22732572).
What are the official names of this protein?
Serine/threonine-protein kinase mig-15, Abnormal cell migration protein 15.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: MECA_ENTFA
Sequence: MEMEHINENTIRVLIGNEDLADRGITFLDLLGNHKDVENFFYSILEEVDVEDEFQGSEAVTFQVLPKNDGLELFISKNVAMDDLSSLEGLSEVNADVSELIRKQIEADKAAADELDEMEATDETNRNVIFELDNFEAMIQLSKEVFMQSVLTNLYTYNDRYYLQVLFLTDELEKTNVDNEIAQILEFAHKTTVTQDTLVEYGTCIMERSALELTRYYFND
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: RS21_STRZT
Sequence: MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVKRKRKSEVARKRKKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: DNLJ_CUPPJ
Sequence: MNATHRGAQADASAPAGGLPPATAAERVQWLRDELDRHNYQYYVLDAPTIPDAEYDALFTELQALEAEHPELLTPDSPTQRVGGAPLSAFDTVRHRVPMLSLNNGFSDEDVTGFDRRCAQGLGRSAAAGGEQDLFSAAEGVEYACELKFDGLAMSLRYEDGRLVQAATRGDGETGEDVTVNVRTIKAIPLKLRGAAPAVLEVRGEVFMYRRDFDKLNARQAEAGDKTFVNPRNAAAGSLRQLDPRITAKRPLSFFAYGLGELQGIERPATHSAMLDGFATMGLPVCNERAVVKGAQGLLDFYRKVGEKRDQLPYDIDGVVYKVNALAEQEQLGFVSRAPRFALAHKFPAQEMTTIVEDIEVQVGRTGAITPVARLQPVFVGGVTVTNATLHNEDEVRRKDVHIGDTVIVRRAGDVIPEVVAVVLERRPDDARAFVMPTACPVCGSHIERLEDEAIARCTGGLICAAQRKQALLHFAQRRAMDIEGLGDKVVEQLVDQGIVRTPADLYKLGVAKLAALDRMADKSAGNLVAAIEASRSTTFNRFIFSLGIRHVGEATAKDLARHFGKLDGLMVADEAALLEVNDVGPVVAQSIVNFFGEPHNVEVIEQLRAAGVHWPESEPVARAPAPLAGKTFVLTGTLPSLSREAAKEMLEAAGAKVAGSVSKKTDYVVAGAEAGSKLDKAEALGVPVLDEAGMLALLESVGAGQPGEQS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MSCL_LACJO
Sequence: MVKEFKEFISRGNMMDLAVGVIIGAAFTAIVNSLVKDLINPLIGLFIGKIDLSNLKFTIGEATFKYGSFLNAVINFLIIALVVFFLIKLVNKITPKKEVEEDPAPTNEEIYLRQIRDLLQEKNK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL29_PORG3
Sequence: MKIAEIKELATKELQERLDAEVAAYDQMRINHAVSPLDSPAKLKHQRRMIAQMKTVLRQRELNK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CYMEN_MELDN
Sequence: GTIPCGESCVYIPCLTSALGCSCKNKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide mden-N.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: RUVC_XANOP
Sequence: MTRILGIDPGSQRTGIGIIDIDEGGRSRHVHHAPLILLGEGDFSQRLKRLLHGLGELIETYRPDEVAIEKVFMGKSAASALKLGHARGAAICAVVMRDLPVHEYAATEVKLALVGKGGADKVQVQHMVGIMLNLKGKLQPDAADALAVAITHAHVRATAQCLGVNTQQAWSRKK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: DAPE_AGRFC
Sequence: MTTTDPVANLAALIRCPSVTPAEGGALSLLDTLLSPLGFAVERVMATEDGTPDVENLYARLGTEGPHLMFAGHTDVVPVGDEAAWSHPPFSADIAGGEMYGRGAVDMKGGIACFVAAIARHIGKHGKPQGSVSFLITGDEEGPSINGTSKLLEWAAAKGETWDACVVGEPTNPDQLGDMIKIGRRGSLSGRITVQGVQGHAAYPHLADNPIRGLLQLTHALMHPAFDHGTDDFQPSNLEVTTVDTGNAATNVIPARATAAFNIRFNDSWTAESLRAEIIRRLDAAANEGELRPDRAPVKYEIVWADRPSHVFLTRNNALISSLSGAIETVTGKEPKLSTTGGTSDARFIKDYCPVVEFGLVGQTMHMVDERVAVADLETLTRIYETFIERWFAHADGK
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RS12_CANAL
Sequence: MSDVEQEQIVEEVVVEEQSGAITIEDALKVVLRTSLVHDGLARGLREASKALSKREAQLCVLCDSVTEESIIKLVEALCNEPEEKIPLIKVSDAKLLGEWAGLCQLDRDGNARKVVGASCVVVKNWGADSDERNILLEHFSQQ
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS12 family.
Protein: THS_DESSY
Sequence: MAQLAGQPVVILPEGTQRYVGRDAQRLNILAARIVAETIRTTLGPKGMDKMLVDSLGDIVITNDGATILDEMDIQHPAAKMMVEVAKTQDKEAGDGTTTAVVIAGELLKKAEELLDQNIHPSIIIKGYALAAEKAQEILEGIAKEVSPDDVETLKKAAVTSITGKAAEEEREYLAEIAVEAVRQVAEKVGDKYKVDLDNIKFEKKEGASVHETQLIRGVVIDKEVVHPGMPKRVENAKIALINDALEVKETETDAEIRITSPEQLQAFLEQEERMLREMVDKIKEVGANVVFVQKGIDDLAQHYLAKYGIMAVRRVKKSDMEKLAKATGAKIVTNVRDLTPEDLGEAELVEQRKVAGENMIFVEGCKNPKAVTILIRGGTEHVVDEVERALEDAVKVVKDIVEDGKILPAGGAPEIELAIKLDEYAKEVGGKEQLAIEAFAEALKVIPRTLAENAGLDPVETLVKVIAAHKEKGPTIGVDVFEGEPADMMEKGVIAPLRVPKQAIKSASEAAIMILRIDDVIAASKLEKDKEDKGGSNDFGSDLD
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit, Hyperthermophilic heat shock protein, HHSP.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: ENO_MESFL
Sequence: MSRIEKIIAREVLDSRGTPTVEVELWTEFGGYGIAKAPSGASTGENEALELRDGDKARYNGKGVLKAVANVNDKIAPALIGHDVQDQLGLDRVMIKLDGTEFKKKLGANGMLAVSLAAAHAAASELEVPLYRYIGGVQAKRLPVPMLNVINGGEHADSAIDFQEFMIMPVGAPTFKEALRWSSETFQALKSLLHDKGDITAVGDEGGFAPHFSWAYAKQDLASFKAKTPAEIALDLLVEAITKAGYKVGKDGIMIAMDCASSELYFEDKKYHFKKIEKVTGQEWAFTTEEMIAYLEKLVNNYPIISIEDGLSEKDWDGFVQLTEKIGDRVQIVGDDLFTTNPRFIKEGISKDAANSTLIKLNQIGTLSETVEAITMTQKAGWTAVVSHRSGETEDATIADLAVAFNAGQIKTGSMSRSDRIAKYNRLLQIEDQLGEDAIYDGYATFYNLKINK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PSBM_SPIOL
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: IOD2_PIG
Sequence: MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGMRCIWKSFLLDAYKQVKLGEDAPNSSVVHVSNPEGSNNHGHGTQEKTVDGAECHLLDFANPERPLVVNFGSATUPPFTSQLPAFSKLVEEFSSVADFLLVYIDEAHPSDGWAVPGDSSLSFEVKKHQNQEDRCAAAHQLLERFSLPPQCRVVADRMDNNANVAYGVAFERVCIVQRQKIAYLGGKGPFYYNLQEVRRWLEKNFSKRUKKT
What is the function of this protein?
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine).  Essential for providing the brain with appropriate levels of T3 during the critical period of development.
What are the official names of this protein?
Type II iodothyronine deiodinase, 5DII, DIOII, Type 2 DI, Type-II 5'-deiodinase.
What is the protein family that this protein belongs to?
Belongs to the iodothyronine deiodinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RUVA_RUBXD
Sequence: MIDRLRGQLVEKDPEGVVVDCGGVGYRAAAPLSTLRALPAVGEECVVHTRMVVREDAMLLFGFATREEREAFDALTSVSKVGPRLALAVLSAMTPGQMMEAAARGDVHRFAAVPGLGRKTAERLVLELRGRELAAAGGGGGVAAGEGDGPFMEAREALTGLGYSLEEAERALRDVPPQETVEQYIKAALRKIGGRR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.