PharMolix/UniProtQA huggingface dataset:
Protein: CCA_SALEP
Sequence: MKIYLVGGAVRDALLGLPVKDKDWVVVGATPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEADLQRRDLTINALARDDDGQIIDPYHGRRDLEARLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLALMREMTAAGELEHLTPERVWKETENALTTRNPQVYFQVLRDCGALRVLFPEIDALFGVPAPAKWHPEIDTGVHTLMTLSMAAMLSPQLDVRFATLCHDLGKGLTPKNLWPRHHGHGPAGVKLVEQLCQRLRVPNDLRDLAKLVAEYHDLIHTFPILQPKTIVKLFDAIDAWRKPQRVEQIALTSEADVRGRTGFEASDYPQGRWLREAWQVAQAVPTKEVVEAGFKGIEIREELTKRRIAAVANWKEKRCPNPAS
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RLMN_MYCGI
Sequence: MPDPLPLVFDAPRRALPPRHFADLADTERAAAVADLGLPAFRGKQLANQYFGRLISDPSQMTDLPAGVRDQVGAALFPELLEAAREIECDRGETRKVLWRAVDKTTFESVLMRYPDRNTVCISSQAGCGMACPFCATGQGGLKRNLSTAEILEQVRFASAELRDREGGRLSNIVFMGMGEPLANYNRVVAAVRRITASSPHGFGISARSVTVSTVGLAPAIRKLADEKLNVTLAVSLHTPDDELRDTLVPVNNRWKVDEVLDAARYYADLTGRRVSIEYALIRDVNDQPWRADLLGRKLHATLGPLVHVNLIPLNPTPGSEWDASPKPVEREFVRRVRAKGVSCTVRDTRGREIAAACGQLAAQG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4137_PSEA6
Sequence: MLGWALTFLIIAILAGVMGFGGIAGTAAGIAKIIFFVFLVLLVLSLVANAIRGKGPKV
What are the official names of this protein?
UPF0391 membrane protein Patl_4137.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECA_NOCSJ
Sequence: MAGGDREKALDAALANIEKQFGKGSVMRLGDEVRAPLEIIPSGSIALDVALGLGGFPRGRVVEIYGPESSGKTTVALHAVANAQRAGGIVAFIDAEHALDPDYAKNLGVDTDALLVSQPDSGEQALEIADMLIRSGALDLIVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKMTGALNNSKTTMIFINQLREKIGVMFGSPETTTGGKALKFYASVRLDVRRIETLKDGTDMVGNRTRVKVVKNKVAPPFKQAEFDIMYGKGISREGGLIDVGVEAGLVRKAGAWYTYEGDQLGQGKENARAFLRDNPDLANELEKKILEKLGVGPTVDQDVAELPAEPIGVGDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YXZG_BACSU
Sequence: MWCFTLDGQQKEIHIDRKLEEMDAPAVDDCYGLAEKNGLIYMLYYGDAVIAAFDETVVRRVWILSDKEPDSEAFDQLAISEEGFLVGTFNCYSADLKSSLYLISADVSQEMEEITCCDSNGEGLDVQQLKLTSYAVYAVASSGVYKQDIQ
What are the official names of this protein?
Uncharacterized protein YxzG.
Protein: ARGA_ECO57
Sequence: MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSSIVNDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPLYHKNIRVTDAKTLELVKQAAGTLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDAIHRQLDSGAIVLMGPVAVSVTGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDDGDIVSELFPNEAQARVEAQEEKGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGALLQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIQRDNTTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERIAAQAKQSGLSKLFVLTTRSIHWFQERGFTPVDIDLLPESKKQLYNYQRKSKVLMADLG
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY_SPIOL
Sequence: MLVTFTEAAATASTSSLISFSLSSPPKFHHKSRIYGCKATFGLRTKPTSWIAAASLSSSTTTTSSCGSSVFDPLGIEQDNSWGVASAWDGVLKFVSQTFESSSGTRKDRSSSARGVAAAIEDSSIDFGDFFKGPLPGKFLTLLGLLALSRLGIYVPLGGVNREAFVGNLDQNSFISTLDSFSGGGIGRLGICSLGIVPFINAQIVFQLLSQVYPKLQDLQKKEGEAGRKKIKQYTQYASVGFALVQAIGQVLFLRPYVNDYSTEWVLSSVILLTLGSVFTTYLGERISDLKLGNGTSLLIFTNIISYLPASFGRTVAEAYQEGNYTGLAIIVVSFVSLVFGIVYVQEAERKIPMNYASRYSGKSGGLQKSAYLPFKVNSAGVMPIIFSTSSLSLPATLARFTGLDILKKAAVALTPGGSFYLPTNILLIAFFNYYYTFLQLDPDDVSEQLKRQGASIPLVRPGKSTAAYIKTVLSRISVLGSGFLAILAAGPAVVEQATHLTAFRGFAGTSVLILVGCATDTARKVQAELISQKYKNIEFYDLEK
What is the function of this protein?
The central subunit of the protein translocation channel SecYE.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug (By similarity).
What are the official names of this protein?
Preprotein translocase subunit SECY, chloroplastic, CpSecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GLUQ_PSEAB
Sequence: MTSSYVGRFAPTPSGYLHFGSLVAAVASYLDARAVGGRWLVRMEDLDPPREVPGAQQAILETLERYGFEWDGAVERQSERFPAYAAVVEQLLRSGLAYACTCSRKQLEGFAGIYPGFCRDAGHAREDAAIRLRVPELEYRFVDRVQGEVRQHLGREVGDFVIQRRDGFYAYQLAVVLDDAWQGITDIVRGADLLDSTPRQLYLQELLGLSQPRYLHVPLIVQPDGHKLGKSYRSPPLPAEQAAAPLTRALRALGQRPPAELAQASASEALAWGVAHWDATRIPRCATLPEERL
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: SDN4_ARATH
Sequence: MDYLQAMRLREANRLMIAKFKKESPANDSPEQRLVRLTNENPQYNVDFLFHSYSKDWFVSDVGMKMSNVMIPNQMLALDCEMVLCEDGTEGVVRVGAVDRNLKVILDEFVKPHKPVVDYRTAITGVTAEDVQKATLSLVDIQEKLRPFLSAGAILIDHPIVIDTSLVFKYPNSRKLRRPSLNTLCMSVLGYEVQKAGVSHHCVHDAAAAMKLALAVIKKRVDTTITLTKEAEKSRLFLHRIPHHLSSEELKKDLALKFFPKNFTIDVKPAKTQGGYYCAVVIFGSSVEANQAFENVNGYKETDSSGLPQKLISCSISTFYVR
What is the function of this protein?
Putative 3'-5' exonuclease degrading single-stranded small RNAs.
What are the official names of this protein?
Putative small RNA degrading nuclease 4.
What is the protein family that this protein belongs to?
Belongs to the REXO1/REXO3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YACG_AERHH
Sequence: MVTKVKCPTCQTELEWGPQSPFRPFCSKRCQLIDLGEWADEEKRIPGEIDPELLPYPEEGEQWQ
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: Y1394_STRPM
Sequence: MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVDWFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDRWNEKNQEVLSQFRAVDFVKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLLTFDRLNDMSQS
What are the official names of this protein?
UPF0398 protein M28_Spy1394.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: ANGE1_RAT
Sequence: MIASCLYYLLLPAARLFRFLSDAFFTCRKNALLAKSSSPQVEGNFAMAPRGPDQEECEGLLQQWREEGWNQTLSTASEGPLADKGLAESSLALLMDNSGEQDTASEDKWSSRQLSDLRAADNLDQPFPEVLGEEPLAEDEGPLWAAVPVQTGPQYADCAVLPMGAMAAEQWEEDPAMVAWSIAPEPMPQEETSMWPFEGLEQLQPPPMEIPYHEILWREWEDFSTQPDAQGLEAGDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFANLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMGFTCFYKRRTGCKTDGCAVCYKPTRFRLLCASPVEYFRPGLELLNRDNVGLVLLLQPLVPEGLGQVSVAPLCVANTHVLYNPRRGDVKLAQMAILLAEVDKVARLSDGSHCPIILCGDLNSVPDSPLYNFIRDGELQYNGMPAWKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSERLKYGRDFLLRFRFCDLACQRPVGLVLMEGVTDTKPDRPAGWAECIFEEEISELEPVFPRTIGTIQHCLHLTSVYTHFLPQHGRPEVTTMPLGLGMTVDYIFFSAESCENENRSDHRLDRDGTLKLLGRLSLLSEEILWAANGLPNPFYSSDHLCLLASFGMEVTAP
What are the official names of this protein?
Protein angel homolog 1.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
Protein: RL11_STRPB
Sequence: MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTRAQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: ATG4A_ARATH
Sequence: MKALCDRFVPQQCSSSSKSDTHDKSPLVSDSGPSDNKSKFTLWSNVFTSSSSVSQPYRESSTSGHKQVCTTRNGWTAFVKRVSMASGAIRRFQERVLGPNRTGLPSTTSDVWLLGVCYKISADENSGETDTGTVLAALQLDFSSKILMTYRKGFEPFRDTTYTSDVNWGCMIRSSQMLFAQALLFHRLGRAWTKKSELPEQEYLETLEPFGDSEPSAFSIHNLIIAGASYGLAAGSWVGPYAICRAWESLACKKRKQTDSKNQTLPMAVHIVSGSEDGERGGAPILCIEDATKSCLEFSKGQSEWTPIILLVPLVLGLDSVNPRYIPSLVATFTFPQSVGILGGKPGASTYIVGVQEDKGFYLDPHEVQQVVTVNKETPDVDTSSYHCNVLRYVPLESLDPSLALGFYCRDKDDFDDFCLRALKLAEESNGAPLFTVTQTHTAINQSNYGFADDDSEDEREDDWQML
What is the function of this protein?
Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.  The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine (By similarity).  Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.  In addition to the protease activity, also mediates delipidation of PE-conjugated ATG8 proteins (By similarity).
What are the official names of this protein?
Cysteine protease ATG4a, Autophagy-related protein 4 homolog a, AtAPG4a, Protein autophagy 4a.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_LISMO
Sequence: MEWSEVEVHTTNEAVEPVANVLTEFGAAGVSIEDVADFLREREDKFGEIYALRREDYPEDGVIIKAYFLKTTEFVEQIPEIEQTLKNLSTFDIPLGKFQFVVNDVDDEEWATAWKKYYHPVQITDRITIVPSWESYTPSANEIIIELDPGMAFGTGTHPTTQLCIRALSNYLQPGDEVIDVGTGSGVLSIASAKLGAKSILATDLDEIATRAAEENITLNKTEHIITVKQNNLLQDINKTNVDIVVANILAEVILLFPEDVYKALKPGGVFIASGIIEDKAKVVEEALKNAGLIIEKMEQQGDWVAIISKRGVE
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSOSA_HYDCU
Sequence: MSDYGIALGMIETRGLVPAIEAADAMTKAAEVRLVSREFVGGGYVTVLVRGETGAVNAAVRAGADACERVGDGLVAAHIIARPHKEVEPVLTMEQK
What is the function of this protein?
One of shell proteins of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, ccbL-ccbS) is sequestered.  Assembles into hexamers which make sheets that form the facets of the polyhedral carboxysome.  The shell probably limits the diffusion of CO(2) into and out of the carboxysome.
What are the official names of this protein?
Carboxysome shell protein CsoS1A.
What is the protein family that this protein belongs to?
Belongs to the bacterial microcompartments protein family. CsoS1 subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.
Protein: PROA_ACET2
Sequence: MSISEMAFQVKEASIRLAAAGTELKNKALENIARLLMERKDEIIKANNEDLQRSREEKLAEPLLKRLKFDEAKIVDVIDGINSLIKLEDPVGKTLLSTELDEGLELYRVTCPIGVVGIIFESRPDALVQISTLCLKSGNGVLLKGGSEARETNKILAQIITEATEEVGIPPNWIKLLETRADVNEMLKMDKYIDLIIPRGSNEFVRYIMDNSRIPVMGHADGICHCYIDEDADIDMAIRIVVDSKTQYVAVCNATETLLVHKNIAPKVLPELKRALDSKNVELVGCSETQKIIPVAPATEEDWRTEYLDYKLSVKVVGDLEEAIEHINTYGSGHTDSIITNSKEKAAAFMSLVDSGNVFWNCSTRFSDGFRYGFGAEVGISTSKIHARGPVGLDGLLIYKYKLIGNGHIVEDYAKRTKSFKHNKMNKQFPL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURF4_DROME
Sequence: MSIPNEYIAKTEDVAEQVIKRGKNVLPTVARLCLIATFFEDGLRMYIQWNEQREYMDMSWGCGKFLATVFVLVNLLGQLGGCGMVMARFKVDIAVGLLFFIVVLQTVAYSILWDFQFLLRNFALIGALLLVLAEARIEGRSLFAGVPSMGENKPKNFMQLAGRILLAFMFITLIRFELSVWQVIQDIIGSILMVLVVLGYKTKLSALILVALLTILNLYHNAWWTIPSYKPLRDFLKYDFFQTLSVIGGLLMIVSLGPGGVSMDEHKKKW
What is the function of this protein?
Endoplasmic reticulum cargo receptor that mediates the export of lipoproteins by recruiting cargos into COPII vesicles to facilitate their secretion.
What are the official names of this protein?
Surfeit locus protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the SURF4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FPG_PSEF5
Sequence: MPELPEVETTRRGIAPHLEGQKVSRVIVRDRRLRWPIPEDLDVRLSGQRIVLVERRAKYLLINAEVGTLISHLGMSGNLRLVEVGLPAAKHEHVDIELESGLALRYTDPRRFGAMLWSHDPLNHELLVRLGPEPLTDLFDGERLYQLSRGRSMAVKPFIMDNAVVVGVGNIYATEALFAAGIDPRREAKGISRARYLKLAIEIKRILAAAIERGGTTLRDFIGGDGQPGYFQQELFVYGRGGENCKVCGTGLREIKLGQRASVYCPRCQS
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RRG1_CANGA
Sequence: MITHFCELAAHRNYVLALYRHSLRNVSRINSGFVKHKMKKVITNEARKHKNDKSSWSIYRRLKELKLLSDKLEDDQVNDAYNLLDSFMKSVKKPKNELKGHLMKIRTEIETNKNIQDKTRLTRLNLLHRYIAKKQQNQLLTKHIPDEYKEKLLLPLALHEKGILRLAAIRNQFKKGGYHAKLSFTMAGKTRIWFIRSMLNKRKKQSLRLRNLITSEKRRYLEVCKIVESLNENANWALHEAIWERYLDDGYLHATSSKGYLKMVEIEDNSVKLQNQNDSKVVKCQRLQQWLSPIQSSILSLENYLNQRQMKYAKLKTKILEPKGVYDYYQKKSKRVFQNHMKTYKRMVKNELPFVNPFIERLSIGSILKRNGINVKY
What is the function of this protein?
Essential for respiratory growth and required for mitochondrial protein synthesis.  Required for vacuolar acidification (By similarity).
What are the official names of this protein?
Required for respiratory growth protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPC1_BPD3
Sequence: MELKDRIKAARKHAKLTQAQLAQRVGLDQTSISNLEQGKSQGTSYIAQLASACGVSALWLAAGHGEMNSNKEALPGAPSEKDYALIPQYTARGECGDGYFNDHVETTEGLVFKRDWLKRVNSKPENLFVIYADGDSMEPYIFEGDVVLFDTSKTDPQDKQVYVIRRPDGGVSIKRLNQQLTGAWLIRSDNPDKSAYPDEMASESSVHELPIIGRVIWRGGGIG
What are the official names of this protein?
Repressor protein CI.
Protein: ARGC_ACET2
Sequence: MASVGIIGATGYVGTEIVRLLQNHPDINITSVVSHNFAGQKISDIYPNLKNVFEMECDELDIDKIADKAEVFVTALPHGISKEVIPKLVEKGKRIVDHSGDFRYKSVEVYEKWYNATHGMPHLLKLSAYGLPELHREEIKNAQIIGNPGCYPTCSILALAPLVKNRLVDTKNIIIDAASGVSGAGRKTDLPYQFCECDENFKAYSVSNHRHTSEIEQELSLLAEEEITVSFTPHLVPMKRGMLATIYANLNCEKSTSELIELYKEYYKNEYFVRILDEGKLPETKFVAGSNFIDIGLVVDKRLNRVVILSAIDNLGKGAAGQAVQVLNILFGLPEHRGLTNPGFYL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y9533_DICDI
Sequence: MTIIESILSIATVQNNSNNNNNQKTPFANVYQLYNSTILFNNNQLTRKRIR
What are the official names of this protein?
Putative uncharacterized protein DDB_G0276161.
Protein: SYL_LYSSC
Sequence: MSFNHQQIEKKWQQYWADNKTFKTENETEKPKFFALDMFPYPSGAGLHVGHPEGYTATDILSRFKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTAKNIATFKRQIQELGFSYDWDREINTTDPAYYKWTQWIFIQLYKKGLAYVDEVAVNWCPALGTVLANEEVIDGKSERGGHPVERRPMKQWMLKITAYADRLIDDLEEVDWPESIKDMQRNWIGRSEGAEVTFGIDGTDENFTVFTTRPDTLFGATYCVLAPEHKLVEQITTVEQRQAVEDYLEKVKMKSDLERTDLAKEKTGVFTGAYAVNPINGKKVPIWIADYVLVSYGTGAIMAVPAHDERDYEFASAFSLDIVPVLEGGDISKEAFTGDGQHINSDFLNGLNKVEGIAKAIEWLEEKGVGEKKISYRLRDWLFSRQRYWGEPIPMIHWEDGTITPVPEEELPLMLPKTDNIRPSGTGESPLANIAEWVNVVDPATGKKGRRETNTMPQWAGSSWYFLRYIDPTNTEAIADPELLKRWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVHTKEPFQKLFNQGMILGEGNEKMSKSKGNVVNPDEIIESHGSDTLRLYEMFMGPLEASVAWSTNGLDGARRFLDRIWRLLVNEEDGTISAKIQVSDDKTLEKSYHQTVKKVTEDYEGIRFNTAISQMMVFINDCYKAEVIPTAYAEGFVKMLAPIAPHIAEELWNLLGHEGTLSYEQWPTYDESKLVDDEVEVAVQVAGKVRAKIVVAKDASKEDIEKVALADEKVQEYMAGKDLVKVIVIPGKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2265_METBU
Sequence: MRTLVFEPFSGASGDMILAGLIDLGADKGEIVEVIQASVDVSVTIEDITKCGIRATDVNIHTKDSARIRSFGELIDIIKDANLPEEVEKNAIAVFRIIGDAEAKVHGMSLEQLHFHEVGQDDALADVIGSCYAIHRMKVENILCTPVNVGGGSVRTAHGTLPVPVPATTEILSGSGLEVHSNGDRELLTPTGAALLTYFANPSDQLPTGKILTTGYGAGDAETDMPNVLRTMLMETTGNLSRDHMEVLETNVDDVTGEVLGNLFETLMKEGAKDVTITPATMKKGRTGHIIHVIAHPENSERIARELIRQTGTLGVRILPTKHRFIAERKMEKVNIIIGKQTFQVTVKIAHDRSDEVLHISAEFEDCRRISQECGLPLKEVIRRAEEKAWNNILKK
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: C_SENDO
Sequence: MASATLPAWIKMPSFLKKILKLRGRRQEDESRSRMLSDSSTQSYQVNQLTSEGTEAGSTIPSTPSKGQALPTESKVRAREKSRHRRPKIIDQVRRVESLGEQASQRQKHMLETLINKIYTGPLGEELVQTLYLRIWAMEETPESLKILQMREDIRDQVLKMKTERWLRTLIRGEKTKLKDFQKRYEEVHPYLMKEKVEQIIMEEAWSLAAHIVQE
What is the function of this protein?
The different products prevent the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways.  They inhibit IFN-alpha/beta induced tyrosine phosphorylation of STAT1 and STAT2.  Blocking the IFN-alpha/beta pathway requires binding to STAT1 in the cytoplasm.  They inhibit IFN-gamma induced serine phosphorylation of STAT1.  Block the IFN-gamma pathway by binding to and stabilizing the parallel form of the STAT1 dimer, further inducing high-molecular-weight complex formation and inhibition of transcription by IFN-gamma.  May also have a role in preventing the cell to enter apoptosis.  Modulate regulation of viral transcription and replication.  Overexpression inhibits the viral RNA polymerase.  The absence of all C', C and Y1 proteins leads to viral delayed growth.  Plays an important role in virion particles release.  Modulates virion shape.
What are the official names of this protein?
Protein C'.
What is the protein family that this protein belongs to?
Belongs to the respirovirus protein C family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Protein C' seems to localize around the Golgi.
Protein: RIP16_CRIRI
Sequence: MKIIVFLAVLMLVSAQVCLVSAAEMEHSSDNELSSRDLVKRFPLPSCVYTRTCGKRDIESSEGANGGE
What are the official names of this protein?
Riparin-1.6.
What are the subcellular locations of this protein?
Secreted.
Protein: ESR2_MACMU
Sequence: QLHCAGKAKRSGSHAPLVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSNMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLSMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAE
What is the function of this protein?
Nuclear hormone receptor.  Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
What are the official names of this protein?
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYI_CLOAB
Sequence: MYKKVDSSKSFVDIERDVLKLWHEKEIVKKSFNSNQDGEYFSFYDGPPTANGRPHVGHIITRVMKDLIPRYKVMKGYKVPRKAGWDTHGLPVELEIEKKLGISGKPQIEEYGIEKFVKECKESVFSYVSLWKDMSEKLGYWVDMENPYVTYHNDYIESVWWALKQMWDKDLLYKGHKIVPYCPRCGTALSSHEVAQGYKDVKEATAFVKFKVKGEENKYILAWTTTPWTLPSNVALAINKAYDYVEVINNGEHLILAKALLTVLEGEYEVVSEFKGEKLLGMEYEQLFKFANPDKKAFYVVHGDFVTLSDGTGIVHIAPAYGEDDNMLGKKYDLPLINLVNGEGKFVDEVEPWKGLFVKKADPKILEYMKENGTLYKSEKFTHSYPHCWRCDTPLLYYPRDSWFVRMTSLRDKLVENNNKIHWYPDNIRTGRFGKFVENVIDWGISRDRYWGTPLPIWQCECGHRDCVGSIEELKEKGINVPENIELHKPYIDEVKLTCPKCGKPMTRTEEVIDCWFDSGSMPFAQLHYPFENKEVFENTFPAQFISEAVDQTRGWFYTLLAISTSIFDKSSFENCIVLGHVLDKHGLKMSKHKGNVVDPFDVLDNQGADACRWHFYTSSAPWLPTRFSQEDVAETQRKFLSTLWNVYSFYVLYAEIDKFNPNDYKDFVSGNVMDKWIVSRLNTLTKDVGNYLDSYGITQAALEIQDFVDDLSNWYVRRNRSRYWTQELTDDKVGAYVTLYRVLVTLSKVAAPFIPFMTEQIYQSLVTSINEGAEESVHLCKWPEYDESLIDSSLEEEMKLAISIVKLGRSARNGANIKNRQPLYEMRVSTKALPDYYGDIIRDELNVKKVEFGADLSKYVNFEIKPNLPVLGKSYGKLIPKIRKEISSMDQMKLAERVRSGEAVKIDVDGTEIELNSENLLVTMQGLEGFAFAGIGEIGIVLETTITDELREEGYLREVLSKVQNMRKESGFEVADKIEIYVSGNEKLENVIRKFEDTIKKETLATDIIYSENKEAAIYNINGEELNVFVKKNC
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.