PharMolix/UniProtQA huggingface dataset:
Protein: RS6_BRUA4
Sequence: MALYEHVLLARQDISQQQVDALVEQYKGVLEANGGKVGKVESWGLRPLTYRIKKNRKAYYTLVNIDAPAAAVAEMERQMRINEDVLRFLTVRVEEHEEGQSAMLTRRDDRRERDGDDRPRRREGGFDRGDRGDRGDRGPRRPRDNEAGEGA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: CD123_KLULA
Sequence: MAAESYTPLVDIKVRSDDIRACSFSSWYDKFKKYTPKAKIIQPLPEEFLRYLAQDGIRLSLEENDSTYNDHCLKRDDDNEYSDWEADDDGDNDSDSDDDKNGKEEEMVPMVNFPDLHREIAEVIGEYGAVTPKLNWSAPRDATWILPNNTSKCMNVNDIYLLLNASNYIAYDLDHAFDECEDRDNSDNQSIQFELVLRKWFDINPALEFRVFVRDSEIWGISQRDLNYYNYLEPLQDTFTNLIEEFVYDIVLPNFDLKSFVLDVYLPRPFESCWLIDINPWSRTTDPLLFSWNELASKDLDSDASPEIRLITEHNMGRFVTKEHSENQVPKDVVQASLDPESMRELTYKWKEILKMQEAESDSDSN
What is the function of this protein?
Regulates the cell cycle in a nutrient dependent manner.
What are the official names of this protein?
Cell division cycle protein 123.
What is the protein family that this protein belongs to?
Belongs to the CDC123 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAT_SHIB3
Sequence: MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPKRDVNTVSEPDSQIPPGFRG
What is the function of this protein?
This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response.  It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.
What are the official names of this protein?
Primosomal protein 1, Primosomal protein I.
What is the protein family that this protein belongs to?
Belongs to the DnaT family.
Protein: HISX_BRADU
Sequence: MPVRLDRSSADFDQRFAAFLAAKREVSADVEAAARAIVDDVARRGDAALLEATAKFDRLTLDASGLRVSAAEIEAAVKACDAATLDALSLARDRIETYHRRQLPKDERFTDPLGVELGWRYTAIESAGLYVPGGTAAYPSSVLMNAVPAKVAGVSRLVMVVPSPDGKLNPLVLAAARLGGVTEIYRVGGAQAVAALAHGTATIAPVAKIVGPGNAYVAAAKRLVFGKVGIDMIAGPSEVLVIADDTGNADWIAADLLAQAEHDTSAQSILITDSARLAADVEKAVEAQLKTLPRTAIASASWADFGAIIMVKNLNDAIPLADAIAAEHLEIMTTDPDALAARIRNAGAVFLGAHTPEAIGDYVGGSNHVLPTARSARFSSGLSVHDFMKRTSILKCGPDQLRALGPAAMTLGKAEGLDAHSRSIGLRLNLS
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: CD158_MOUSE
Sequence: MESKACESKNEDLLPSGITSKGGSSSPFFVTSTHGTIIENTSSTGTLTQMPFFPKYEVELDSPRKSTPYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEESRNQLQNTVRELEAAKCLKEDMLKDSSTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKICEHDSMSTMHFRSLGSAISKILRELDTEISFLKGRIFPVEDQLETLKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSVQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELRESKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMNLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRKLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIRHERDQLLNEVKTSRTELNHLSEDYEVLKRNFRNKSEEMESTTNRLKMQLKSAQSELEQTRNTLKTMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKVQFLEEAVTSANKERHFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKFAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSVKPRLLQPASVTRSHSNIPSSQSTTSFLSHHSIKTNTPKEDPTRDLKQLLQELRTVINEEPAMALSKTEEDGRTPSLGALEDRVRDCITESSLRAELCHRSNNSLRESTEGSKSSETLSREPVPLHPGDLEDPSSCFTFTSTASPSGKMSASRSFSSSPKKSPVHSLLTSSAEESVNSTPQYRSTKPIHSPTSAKDSQSPSLETTGKTCQKLQNRLESLQTLVEDLQLKNQAMSSMIRNQEKRIQKVKDQEKMLLK
What are the official names of this protein?
Coiled-coil domain-containing protein 158.
Protein: RTCA_GLOC7
Sequence: MLDIDGSWGEGGGQILRTTLSLSAITGQPIRLYQIRAGRQKPGLSAQHLTCVRAAATICNAEVRGDKLRSTLLEFIPTRPPQAGHYTFDVMDAQEGGSAGAVTLILQTILLPLAIASEESTVILKGGTHVAWSPPISYIEQVYLPLLSKLGLQTELHLQAWGWYPQGGGEVHLHIKGNCQLQGVELLERGALKQVKGLAVVTELPSHIPQRMAMRCEKLLQQAHVKGYVQPLRAKGVAPGAGVFLTSEYEHICAGFAALGRRGLPAESVAQNAVEQLLSFHQQDAPVEEFLGDQLLLPMILAQSPSQYRVAHISEHLKTNVQTISQFGLAQIDLNLEDRLVFVKPGHNLT
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESXB_STAAM
Sequence: MGGYKGIKADGGKVNQAKQLAAKIAKDIEACQKQTQQLAEYIEGSDWEGQFANKVKDVLLIMAKFQEELVQPMADHQKAIDNLSQNLAKYDTLSIKQGLDRVNP
What is the function of this protein?
Virulence factor that is important for the establishment of infection in the host.  EsxB is required for EsxA synthesis as well as secretion (By similarity).  Mediates together with EsxA the release of S. aureus from the host cell.  Inhibits also host cytokine production and thus modulates dendritic cell-mediated immunity (By similarity).
What are the official names of this protein?
Type VII secretion system extracellular protein B, Ess extracellular protein B.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESAT-6 secretion system (Ess) / type VII secretion system (T7SS).
Protein: TRMA_ECOLU
Sequence: MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQCETIFVDPPRSGLDGETEKMVQAYPRILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: Y1004_STAAW
Sequence: MNLIPRTSIVVYLKHMKHERQIRKYGHIVHSNRDRKFVIMYVNEQDVDQIVHKLMQLKYVRHIDGSPYKYLKKTYEKEKHEIYN
What are the official names of this protein?
UPF0298 protein MW1004.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_PECAS
Sequence: MSEQVIIFDTTLRDGEQALQASLSVKEKLQIAFALERMGVDVMEVGFPVSSPGDFESVQTIARNIKNSRVCGLTRCVEKDIDVAAEALRVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMIKRARNYTDDVEFSCEDAGRTPIPDLCRVVEAAINAGARTINIPDTVGYTMPHEFGNIIASLYQHVPNIDKAIISVHTHDDLGLAVGNAMAAVHAGARQVEGTLNGIGERAGNCSLEEVIMAIKTRHDILNVHTNINHQEIYRTSQLVSQICNMPIPANKAVVGANAFAHSSGIHQDGVLKNRENYEIMTPESIGLKEVQLNLTSRSGRAAVKHRMEEMGYQDNDYNLDDLYSAFLKLADKKGQVFDYDLEALAFISRQQEEPEFYHLDYFSVQSGSSVMATASVKLICGEETQSEAATGNGPVDAVYQAINRITGYQVSLVKYQLTAKGQGRDALGQVDIVADYQGRRFHGVGLATDIVESSAQAMVNVLNNIKRAQQVEKEIQRLQQHNNQQQNDSKQQNSQETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: CMC4_YEAS2
Sequence: MSNPCQKEACAIQGYCLLSHQYDDAKCAKVIDQLYICCSKFYKDNGKDSRSPCCPLPSLLELKMKQRKLTPGDS
What are the official names of this protein?
Cx9C motif-containing protein 4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the CMC4 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Imported into the mitochondria via the mitochondrial disulfide relay system.
Protein: NHAB_VIBA3
Sequence: MPMSLGNAFIKNFLGKAPDWYKLAIISFLIINPFVFFLVDPFVAGWLLVVEFIFTLAMALKCYPLQPGGLLAIQAVAIGMTKPEMVYHELQANLPVLLLLVFMVAGIYFMKELLLFIFTKILLGIQSKILLSVAFCVAAAFLSAFLDALTVIAVVISVAVGFYSIYHKVASGKGTTSAHDHTHDEEISELTRDDLENYRAFLRSLLMHAGVGTALGGVMTMVGEPQNLVIAKQAGWEFGEFIIRMLPVTLPVFFCGILTCALVEKFKVFGYGAELPNNVRQILVEFDNKERANRTKQDVAKLWVQSAIAVWLIVGLALHVAEVGLIGLSVIILATAFTGVIEEHSMGKAFEEALPFTALLAVFFAVVAVIIDQALFKPVIDAVLHVEDKGAQLALFYVANGILSMVSDNVFVGTVYINEVKTALVEGVITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVIMALPYTIVLALVGLAGIVFFVEPMTAWFYDAGWIIHRTGEVVAPVISGGH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMB_PHOPR
Sequence: MSNDMIFGIHAVKAVLATDPVRLIEVFVLKDRQDDRLMPLLTELKDLGITIQHAGRKALDDKAKGASHQGIIARVKPAKQLNEHDLDTILEGSENPLLLILDGVTDPHNLGACLRNADAAGAVAVIIPKDRAAQLTATASKVACGAAEVMPLVRVTNLARTMRALQDKGVWIVGTAGEATHDIYHSKLTGPLAIVMGAEGEGMRRLTRETCDDLIKIPMAGSVSSLNVSVATGICLFEAVRQRQI
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LON_CAMC1
Sequence: MQINENKGFPTEIPIIVEDELFLYPFMITPLFLSDEENLKALELAIQGETPILVVPTKPQQDGARDFDGIYDAGVIGTIMRRVPLPDGRVKVLFQGIDKGKILKQSGINPLRGIVDMLHVKRPSQVKTDALIVVLREKVRELSQFNHFFPPDLLKTIEESAEAVRVCDLVSSALRLKKQIAYSFFVEENLEQRLLKLIDYVIEEIEANKLQKEIKNKVHSKIDKTNKEYFLKEQLKQIQAELGADTSREEELEEYRKKLDAKKKFMAEDAYKEIKKQIDKLSRMHPDSADANTLQSYLDWVLEIPFENVAKKKSSIAEVSKHLNADHYSLEKPKERIEEYFALRELLELRGVGEKVNNGAILCFAGPPGVGKTSLANSIAKALKRELVRIALGGLEDVNELRGHRRTYIGAMPGRIVQGLIEAKQMNPVVVLDEIDKVGRSYRGDPTAVLLEILDPEQNNKFRDYYLNFNIDLSKIIFIATANDVSMIPAALRDRMEFIELSSYTPQEKFEIAKKYLLPQELKKHGLKPSDVSISKEALELIISDYTRESGVRNLRRRIADILRKVAKNILTKKNEGKISVTAKNLKEFLEKKVYEIEPADKKDQIGLVNGLAWTSVGGDVLRIEAIRIQGKGSMQITGQLGDVMKESAQIAFSVVKVLIDNKKLKVPMPIVPKFDDDKHKLEASDVYRRYDLHLHVPEGAVPKDGPSAGITMATAIASILTDTKVKHDIAMTGEITLTGRVLPIGGLKEKLIAAHKAGIKTALIPRKNYDRDLVDIPAEVKADMKIIAVDTIDDVLKNALVAKK
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPFGB_GIBZE
Sequence: MEVADPSRAPPEYKDVAWIADTCKLLMGIGWTTNYVGMIYKSLKDETYAMALMALCCNFAWELTYALIYPFGSDLEMYVHFSGLMLNCGVMYTAVKNAHREWGHSPLVLRNLPLIFIICVSGFMSGHVALAAQVGPSLAQAWSAYGCQLLLSVGGLCQLLCRGHSRGASYFLWFSRFFGSLVLVPQDILRYKYWRVDHEYMGSPLYIWFVCIFLLLDGSYGICLWYVRRFERQTAVAHKKKK
What is the function of this protein?
Terpene cyclase; part of the gene cluster that mediates the biosynthesis of diterpenoid pyrones (PubMed:32286350).  The first step of the pathway is the synthesis of the alpha-pyrone moiety by the polyketide synthase dpfgA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Probable).  The alpha-pyrone is then combined with geranylgeranyl pyrophosphate (GGPP) formed by the GGPP synthase dpfgD through the action of the prenyltransferase dpfgC to yield a linear alpha-pyrone diterpenoid (Probable).  Subsequent steps in the diterpenoid pyrone biosynthetic pathway involve the decalin core formation, which is initiated by the epoxidation of the C10-C11 olefin by the FAD-dependent oxidoreductase dpfgE, and is followed by a cyclization cascade catalyzed by the terpene cyclase dpfgB (Probable).  The short chain dehydrogenase/reductase dpfgG then oxidizes the 8S hydroxy group to a ketone and the short chain dehydrogenase/reductase dpfgH reduces the ketone to the 8R hydroxy group to yield higginsianin B (PubMed:32286350).  Higginsianin B is further methylated by the methyltransferase dpfgI to produce the intermediate named FDDP B (PubMed:32286350).  The cytochrome P450 monooxygenase dfgpJ then catalyzes a three-step oxidation at C-27 to generate a carboxylic acid as well as C-26 hydroxylation (PubMed:32286350).  Finally, methyltransferase dpfgK methylates the carboxylic acid generated by dpfgJ, yielding the final diterpenoid pyrones from the pathway which were named FDDP D and FDDP E (PubMed:32286350).
What are the official names of this protein?
Terpene cyclase dpfgB, Diterpenoid pyrone biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the paxB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ARLY_CAMC5
Sequence: MQESLKKMWSGRFSGESSELLEEFNASIGFDKNLYREDIAGSKAHAKMLGACGILKPEEAAAIVAGLDAVLAQIEEGKFEFKTADEDIHMAVEKRLSELIGSELGGRLHTARSRNDQVALDFRLYVLRQNEQIARQIREFIATLTSLASAHLDTLMPGYTHLQHAQPVSLAYHLLAYAFMFKRDFERFISSHERNNLCPLGSAALAGTPHPIRRELVAQELNFAGITQNAMDSVSDRDFALEILFNISVLMTHASRLCEELILWSSQEFGFVTISDAYSTGSSIMPQKKNPDVAELIRGKTGRANGNLIALLTTMKGLPLAYNKDMQEDKEGVFDSVRTATSSLAILNAMMKEAKFNEQNMLAATKKGHLSATDLADYLVREKNVPFRTAHFITGKAVAHAENLGVDLSELDAAQLKSVDENLDENAVKFLNLHASKEARTSAGGTANASVRKQIEELESWLSKSGD
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITR1_YEAST
Sequence: MGIHIPYLTSKTSQSNVGDAVGNADSVEFNSEHDSPSKRGKITLESHEIQRAPASDDEDRIQIKPVNDEDDTSVMITFNQSLSPFIITLTFVASISGFMFGYDTGYISSALISIGTDLDHKVLTYGEKEIVTAATSLGALITSIFAGTAADIFGRKRCLMGSNLMFVIGAILQVSAHTFWQMAVGRLIMGFGVGIGSLIAPLFISEIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNGWRILVGLSLIPTAVQFTCLCFLPDTPRYYVMKGDLARATEVLKRSYTDTSEEIIERKVEELVTLNQSIPGKNVPEKVWNTIKELHTVPSNLRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSGTNFIFTLVAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFHFLGIKFDGAVAVVVSSGFSSWGIVIIVFIIVFAAFYALGIGTVPWQQSELFPQNVRGIGTSYATATNWAGSLVIASTFLTMLQNITPAGTFAFFAGLSCLSTIFCYFCYPELSGLELEEVQTILKDGFNIKASKALAKKRKQQVARVHELKYEPTQEIIEDI
What is the function of this protein?
Major transporter for myo-inositol.
What are the official names of this protein?
Myo-inositol transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ANMK_COXBU
Sequence: MPKERYIGLISGTSMDALDTALVQFDPLKIIATHGEPIPTELKKNLVALSTGTDNSIPSMGETDVALGRLFGEAVLTLLEKAKVSSDSIQAIGSHGQTIRHMPNGKHPFTLQIGDPNTIAALTGITTVADFRRRDMALGGQGAPLAPAFHEFLLRDQSENRLILNIGGIANLTFLPRDPEKSTIGFDTGPGNTLLDAWCLMNLNKDYDDQGQWAASGRVQEKLVAQLLAEPYFQTPPPKSTGREYFNLNWLKKNLNGEKFDPVDIQATLVELTARSVANCCRNFSMDSGSLWLCGGGARNHHLVNRLKVLCKPLRVTTTEEIGIHPDWLEAVCFAWLAKQTLEKKPGNLPSVTGAKKSAILGAIYWGEKFNY
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: SPOP_DANRE
Sequence: MSRVPSPPPPAEMTSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPDCRLADELGGLWEHSRFTDCSLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEAEVFKEMMFFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCTSLSVENAAEILILADLHSADQLKTQAVDFINYHASDVMETSGWKSMVASHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
What is the function of this protein?
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.
What are the official names of this protein?
Speckle-type POZ protein, HIB homolog 1, SPOP1.
What is the protein family that this protein belongs to?
Belongs to the Tdpoz family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: E13A_SOLLC
Sequence: MAFLSSLLASLLLVGLLIQITGAQPIGVCYGKIANNLPSDQDVIKLYNSNNIKKMRIYFPETNVFNALKGSNIEIILDVPNQDLEALANPSKRQGWVQDNIRNHFPDVKFKYIAVGNEVDPGRDSGKYARFVGPAMENIYNALSSAGLQNQIKVSTATYLGLLTNTYPPRDSIFRDEYKSFINPIIGFLSRHNLPLLANIYPYFGHADDNVPLPYALFKQQGLNDAGYQNLFDALVDSMYFATEKLGGQNIEIIVSESGWPSEGHPSATLENAMTYYTNLINHVKGGAGTPKKPGRTIETYLFAMFDENRKDGKPSEQHFGLFKPDQRPKYQLKFD
What is the function of this protein?
Implicated in the defense of plants against pathogens.
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase A, (1->3)-beta-glucan endohydrolase A, (1->3)-beta-glucanase A, Acidic beta-1,3-glucanase, Beta-1,3-endoglucanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: GLMU_MYCSS
Sequence: MTSSTTSSTDTAVLVLAAGAGTRMRSDIPKVLHTLGGRSMLAHALHTVAKVAPQHLVVVLGHDRERIAPAVEALATDLGRPIDVAIQDQQLGTGHAAECGLAALPEDFTGVVVVTAGDVPLLDADTMADLLATHGSAAATVLTTTVDDPTGYGRILRTQDNEVTSIVEQADASPSQRAIREVNAGVYAFDITALRSALRRLRSDNAQHELYLTDVIAIFRQDGLSVRARHVDDSALVAGVNDRVQLAALGAELNRRIVTAHQRAGVTVIDPGSTWIDVDVTIGRDTVIRPGTQLLGRTRVGGRCDVGPDTTLSDVTVGDGASVVRTHGSESLIGAGATVGPFTYLRPGTALGAEGKLGAFVETKNATIGAGTKVPHLTYVGDADIGEHSNIGASSVFVNYDGETKNRTTIGSHVRTGSDTMFVAPVTVGDGAYTGAGTVIRRNVPPGALAVSAGSQRNIEGWVVRKRPGSAAARAAERASGEAAEQALGHHDDSQGS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDJE_BACSU
Sequence: MRSHSVVCIGELLIDFFCTDVDVDLMEGRQFLKSAGGAPANVSAAIAKLGGDAAFSGKVGKDPFGYFLKRTLDAVHVDTSMLVMDEKAPTTLAFVSLKQNGERDFVFNRGADALFTLEDIDQEKLNEAKILHFGSATALLSDPFCSAYLRLMSIAKDNGQFISFDPNYREDLWRGRVSEFVSVAKKAIAVSDFVKVSDEELEIISGVKDHEKGVAILHEIGANIVAVTLGKSGTLLSNGKDREIIPSIPVTSIDSTGAGDAFVGAALYQLANTDQIQSVDADFVKLREIVAFANKVGALVCTKIGAIDALPSLDEIGVSL
What are the official names of this protein?
Uncharacterized sugar kinase YdjE.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: RLME_AZOC5
Sequence: MSSSPRSPDARPLKVRVKSARTRSSSSQKWLQRQLNDPYVARAKREGWRSRAAFKLIEMDEKLHVLKRGMRIVDLGAAPGGWSQVAAKKIGAAEGQGKIVAIDLLEMDAVTGVMFAQMDFLDPTAPERLFAMLDGKADLVMSDMAANTTGHKKTDHLKIIALVELAADFARQVLAPGGAFIAKVFQGGTEGTLLADLKRDYAQVRHLKPAASRADSAELYLVATGFRGSADRTEDETDEA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADI_ECOUT
Sequence: MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARTEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLFSRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWSEGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLTDGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTMGDLTLIDMHEAFAAQTLANIQLLGSERFARDVLGRAHATGEVDESKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_PONAB
Sequence: MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGQLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REP_BIFLO
Sequence: MSNEIVKFSNQFNNVALKKFDAVHLDVLMAIASRVRERGTATVEFSFEELRGLMRLKQNLTNKQLADKIVQTNARLLALNYMFEDSGKIIQFALFTVFETDPANQTLEVSVNERFAFLLNDLTSQFTRFELAEFADLKSKYAKEFYRRAKQYRSSGIWKVSRDEFCRLLNVSKSTSDSVSNLNRVVLKPIVEECGPLLGLKIERQYAKRRLSGFVFTFARETPPVIDARPVKAKEEQDSGHWTSVAGYGEVFTTTELFDVTAARDHFDGTVDAGECRYCRYDARNRERHARNAGTLF
What are the official names of this protein?
Probable replication protein rep.
What is the protein family that this protein belongs to?
Belongs to the initiator RepB protein family.