PharMolix/UniProtQA huggingface dataset:
Protein: VPL_BPHC1
Sequence: MFNGRTQDYDDTVITNNGFWSDIYVEEFQKQRAIPLQIPVEMVKAALVAAIQGVDLDLADVAESYRKSAVNSVTEISSPLINDENYAETLYKKAVFARAKAELLPEFNTLSGREIHQNRDYVTEQKSLLAEATHAIRTLKGKKRGSVWLL
What are the official names of this protein?
Probable head completion/stabilization protein, ORF20.
What is the protein family that this protein belongs to?
To phage P2 protein L.
Protein: PYRF_METMP
Sequence: MYGESLVKLMLALDVMDEKKAILIAKETSEYVDSIKIGYPLVLATGLNIIDKIKESTNKEVICDFKVADIPSTNEKIAELTLNHADGIICQGFVGSDSVSAILNVARAKNKKVIVVTEMSHPGATEYLQNVAEDMAKMADRLKVDGIVAPSTRPERLKEIKSIAKDAFVISPGVGAQGGNLSDVLNVLNENDYVIIGRAIYENENPKNAAKKYKIQM
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RS14_AYWBP
Sequence: MAKKSKIVKDQKQRELVLKYSKLRLELKKKADYAGLSQIPAKASPVRLKNRDSIDGRPRGYIRKFGISRINFRQLAHQGKLPGVRKTSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: FMT_MYCMS
Sequence: MQNKIKVVFCGTPKIGADVLKALIEMNQVEIVLVISQPDKPIGRKKQIVHTPVKKLALENNLKVVQPNKIGEIYDDLAKLEFDFLITCAFGQFIPTKILKLAKIDSINFHGSLLPKLRGGAPIQYAIKNGDKKTGITIMQMVKQMDAGDYYVQESIDILDSDDSGSLFEKMGHLAYSMCKKYLVDIYNHKFELIKQNEDEVTFCKNISSEEEKINWNNTSLDIFNLIRSLSPSPISYTTINNQRYKIKSSKVIDLDNQNKNAIPGTILGINKQGIVVKTLDKALLILEIQKEGKKMILASNYYLNKLSDLKINDKFD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SNIP1_MOUSE
Sequence: MKAGKSERERSGRRRHRSGDALTTVVVKQERLSPEPVAHRRPDAPAASLSPPAAEPGHSGHRGSRARSPAKKKSKSSGRRSKSPRTKRSQSPHYPMVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSERDRHRGHSRQGRSSDERPVSGQDRDRDSQNLQAQEEERDFHNARRREHRQQNESAGSEAQEVIPRPAGNRSKEVPVKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSELDRKEDEDDEEEEMVSDS
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).  Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding.  Involved in the microRNA (miRNA) biogenesis.  May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
What are the official names of this protein?
Smad nuclear-interacting protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCP_ENT38
Sequence: MRHILVTGFEPFGGETLNPSWEVVKQLEGMTIDDCRVVTRQLPCVFGESLTLLNSAIDELNPTVVIAVGQAGGRVDITVERVGINVDDARIPDNRGQQPIDVAIVPDGPAAWFSSLPIKAMVAAMREKGIPASVSQTAGTFVCNHVMYGLLHKIRERTNVKGGFIHIPYLPEQAAAHAGAPSMATQTVKAALEIALTVALRQSSDINAVGGATH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_SHESR
Sequence: MTTRYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMNRRNNFTTGRIYEEVLRKERRGDYLGATIQVIPHITNAIKEKVIAGGEGHDVAIVEIGGTVGDIESLPFLESIRQLGVELGRDRTLFMHLTLVPFLGAAGEVKTKPTQHSVKELRSIGIAPDVLICRGDRAIPANERAKISLFCNVEERAVISLKDVDSIYKIPALLRSQGLDDLVVKRFGLECREADLSEWENVIYQEANPNGEVVIGMVGKYIELPDAYKSVNEALKHAGLKNRVSVTIKYIDSQTVEAKGDEVLQGLDGILVPGGFGERGVEGKIQAAKFARENNLPYFGICLGMQVALIEFARNVAGMADAHSTEFNKETPFPVVGLITEWVDEEGNVEQRHEASDLGGTMRLGAQLCHLLEGSKAAQAYKGNSCVERHRHRYEVNNKYRERLEQAGLVFSGLSSDRKLVEMIELKDHPWFVAGQFHPEFTSTPRDGHPLFEGFVAAASAHQKRDLKK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: IAP_ASFB7
Sequence: MFPKINTIDPYISLRLFEVKPKYVGYSSIDARNQSFAIHGIKNYEKFSNAGFFYTSPTEITCYCCGMKFCNWLYEKHPLQVHGFWSRNCGFMRATLGIIGLKKMIDSYNDYYNNEVFVKHKNRVYTHKRLEDMGFSKPFMRFILANAFIPPYRKYIHKIILNERYFTFKFAAHLLSFHKVNLDNQTTYCMTCGIEPIKKDENFCNACKTLNYKHYKTLNFSVKL
What is the function of this protein?
Prevent apoptosis of host cell by inhibiting caspase-3/CASP3 activation to promote the viral replication.  Induces also the activation of host NF-kappaB.
What are the official names of this protein?
Inhibitor of apoptosis protein, IAP.
What is the protein family that this protein belongs to?
Belongs to the asfivirus IAP family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Probably accumulates in the perinuclear cytoplasmic viral factories. Found in association with viral nucleoid (PubMed:30185597).
Protein: PP14C_MOUSE
Sequence: MSVVTGGGEAAGGGGGGGARVFFQSPRGGTGGSPGSSSSSGSSREDSAPVTTVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDANSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV
What is the function of this protein?
Inhibitor of the PP1 regulatory subunit PPP1CA.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 14C, Kinase-enhanced PP1 inhibitor, PKC-potentiated PP1 inhibitory protein.
What is the protein family that this protein belongs to?
Belongs to the PP1 inhibitor family.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein.
Protein: SPT16_GIBZE
Sequence: MAEIKIDSKIFQERISHFATAWKNDLRSKDGLFNGAQSLVVMMGKVEEVPEFHKNNAIHFWLLGYEFPTTLMLFTLDTLYILTTAKKAKHLEQLKGGRFPIEVLVRGKDAAENEKLFVKLTDKIKEAGNKVGTIAKDTSRGPFVDEWKKVLAEHCKEVSQVDISAALSTYAFAVKDESELRAMRTASKACVALMTPYFLDEMSNILDAEKKVKHSTLADKVDKKLDDTSFWKTVQLPSKGKLPSDLDPAQLDWILGPAIQSGGKYDLRFAGESNDDNLHAGIIIAAMGLRYKSYCSTIARTYLVDPNKAQESSYKLLTLIHNTIIKEIRDGMTAKEVYGRAVGIIKSKKPEMEKHFLKNVGWGVGLENKDPTLVLNAKNQRVLKDGMTLIINTGFQDIENPHPQDKNSKVYALVLTDTIRVTSSEPVVFTAEAPTSADANSFFFKDDEETEPAPKKEKKDSRVGAVATKNITTTRLRSERTTQVANDDIEKKRREHQKELAAKKQREGLARFSESTNDQNGGEVKKFKRFESYKRDNQFPVKIKNLEVVVDSKNSTVVLPIMGRPVPFHINTIKNASKSDEGEWSFLRINFLSPGQGVGRKDDQPFEDASAHFVRSLTFRSSDGERYNEIATQISNMKRDVVKKEQEKKDMEDVVEQDKLVEIRNRRPAVLDNVYIRPAMEGKRVPGKVEIHQNGIRYISPLNAQHRVDVLFSNVKHLFFQPCQHELIVIIHIHLKDPIIVGNKKKTKDVQFYREATDIQFDETGNRKRKYRYGDEDEFEAEQEERRRRAELDRLFQGFAQKIAEAGRNEGIEVDMPIRELGFHGVPFRSNVFVQPTTDCLIQVVEPPFMVITIEEVEIAHLERVQFGLKNFDMVFVFKDFTRAPYHVNTIPVEFLDQVKDYLDSSDIAYTEGPLNLNWPTIMKTVTADTHQFFADGGWSFLQADSDDDGGDPSDEESAFEMDEDEFDEESESSDEGSDFGSNASDDEGSDAELDSEDEGEDWDELERKAKKRDRESAMEEEDRGANKKKQRKR
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
What are the official names of this protein?
FACT complex subunit SPT16, Facilitates chromatin transcription complex subunit SPT16.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family. SPT16 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CF136_BOVIN
Sequence: MYQPSRGAARRLGPCLRAYQARPQDQSSPWALPFPPLWPHSTTTTSPSLPLFWSPPPPSPPTRLLPPAPPLPLPQVQALTSPWVVLPPGKGEEGPGPELLSGCLDGLRSLFEGPPCPCPGALIPFQAPGTAHPSPATPSGDPSMEEHLAVMYERLRQELPNLFLHSHDYTLYSSDVEFINEILNMRTKGRTWYILSLTLCRFLAWNYFAQLRLEILQLTRHPENWTLQARWRLVGLPIHLLFLRFYKRDKEELYRTYDAYSTFYLNSNGLICRHRLDKLMPSHSPPEPVKKLLVGALVALGLSEPEPNLHLCSKD
What are the official names of this protein?
Uncharacterized protein C6orf136 homolog.
Protein: FES_FSVGA
Sequence: AARADGTMGFSSELCSPQGHGAEQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMSLQDGGGRGTGPYSPISQSWAEITSQTEGLSRLLRQHAEDLNSGPLSKLGLLIRERQQLRKTYSEQWQQLQQELTKTHNQDIEKLKSQYRALARDSAQARRKYQEASKDKDRDKAKLEQLGPGEPPPVLLLQDDRHSTSSSEQEREGGRTPTLEILKSHISGIFRPKFSLPPPLQLVPEVQKPLHEQLWYHGALPRAEVAELLTHSGDFLVRESQGKQEYVLSVLWDGQPRHFIIQSADNLYRPEGDGFASIPLLVDHLLRSQQPLTKKSGIVLNRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREAADGIYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSIRKRHR
What are the official names of this protein?
Tyrosine-protein kinase transforming protein Fes.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
Protein: M5162_ARATH
Sequence: MVKETVTVAKTCSHCGHNGHNARTCLNGVNKASVKLFGVNISSDPIRPPEVTALRKSLSLGNLDALLANDESNGSGDPIAAVDDTGYHSDGQIHSKKGKTAHEKKKGKPWTEEEHRNFLIGLNKLGKGDWRGIAKSFVSTRTPTQVASHAQKYFIRLNVNDKRKRRASLFDISLEDQKEKERNSQDASTKTPPKQPITGIQQPVVQGHTQTEISNRFQNLSMEYMPIYQPIPPYYNFPPIMYHPNYPMYYANPQVPVRFVHPSGIPVPRHIPIGLPLSQPSEASNMTNKDGLDLHIGLPPQATGASDLTGHGVIHVK
What is the function of this protein?
Probable transcription factor involved in somatic embryogenesis.  Acts as positive regulator of BHLH109.
What are the official names of this protein?
Probable transcription factor At5g61620, Myb-related protein At5g61620.
What are the subcellular locations of this protein?
Nucleus.
Protein: TUSD_ESCF3
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHELSSVFFYREGVYNANQLTSPASDEFDLVRGWQQLNTQHGVALNICVAAALRRGVVDETEAGRLGLASSNLQTGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1497_CLOPE
Sequence: MLKNNEILETISMIKEQNLDVRTITLGLSLMDCACEDVKVLSEKIYDKITKTAENLVKTGENIEKRFGIPIINKRISVTPISIVAASCNCNSYLSIAKAMDKAAKEVGVDFIGGFSALVHKGFTESDLKLIKSLPESLANTDIVCSSVNIGSTRYGINMDAVKLMGETIKETSLITPDGFGCAKLVVFCNAVEDNPFMAGAFHGVGEAEKVINVGVSGPGVVKKALEEVRGKSFEEVAETIKKTSFKVTRMGQLVAKEASKLMDIPFGIVDLSLAPTPAVGDSVGRVLEEMGLSNCGTHGTTAALALLNDAVKKGGLMASSYVGGLSGAFIPVSEDECMIEQSKNGFLTIEKLEAMTCVCSVGLDMIAIPGKTSASTISGIIADEAAIGMINNKTTAVRIIPVPNKDIGDIVEFGGLLGSAPIMRVSPGNCDDFISRGGRIPAPVHSLKN
What are the official names of this protein?
UPF0210 protein CPE1497.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: DEOC_ECO27
Sequence: MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CF217_HUMAN
Sequence: MLNSPGTRRPVKEAQKYGEDSQKSHSPGTPGPRSSVTTLSASALSDSSSPDTPPRRGPGRPSTPARAPATSAPMMYSRRGVRRTARPAGADTRSSANQLPQPSGACANADSAPPADVSACLRRRSHGDRCVPRSRRRPRPRPRASTAFFQEEGPCGACPGALRPQAGASFRELRGLPPPRPREREQSPPLGAAPSSALSHQGWKNTRCATRGLVNTLVNTGHFLYLQPPAPLIMPYLDDAEVPGNRRSHPSLSFSWLSKALYHVTFLLRIL
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00271, AHI1 divergent transcript.
Protein: MUTS_STAA8
Sequence: MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRVLEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNNGYKVAICEQMEDPKQTKGMVRREVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATLLNEITTINPNEVVINDNISDNLKRQINMVTETITVRETLSSEIYSVNQTEHKLMYQATQLLLDYIHHTQKRDLSHIEDVVQYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIERDTLRTYLNQVYDIERLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQNTLVQVNQLEPLDDLLDILEQSLVEEPPISVKDGGLFKVGFNTQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKISFNKVFGYFIEITRANLQNFEPSEFGYMRKQTLSNAERFITDELKEKEDIILGAEDKAIELEYQLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFSENKTLELVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQMGAYVPCKEAVLPIFDQIFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDEIGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHELTTLDQALPSLKNVHVAANEYKGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLKMVENEPEINQENLNLSVEETTDTLSQKDFEQASFDLFENDQKSEIELQIKNLNLSNMTPIEALVKLSELQNQLK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PURT_MARSD
Sequence: MVTLGTAGTASARKMMLLGGGELGKEVVIEAQRLGVEVIVVDRYENTPAMQVAHRSYVISMLDTAELRRVVETEKPDYIVPEIEAIATETLLELEKEGFNVVPTARATRLTMDREGIRRLAAEEVGLKTSPYKFADTKEEYLEAIKEIGIPCVIKPVMSSSGKGQSTVKSEADVDRAWDYSQSGGRTGEGRIIVESFVDFDYEITLLTVRHAGGTSYCAPIGHRQDDGDYRESWQPQPMSDAALANAQDYALRITDALGGRGLFGVELFIKGEEVIFSEVSPRPHDTGLVTVISQDLSEFALHVRAILGLPIPAIRQYGPAASSVILSNGKSEAPAFANVDKALEAADTKVLIFGKGECNGVRRLGVALALGEDVTDAKARAIRASSAVEIEY
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: MNMG_SYMTH
Sequence: MGLTKEYDVIVVGAGHAGIEAALAAARKGMRTACFTTTLENIGAMNCNPSIGGPAKGHLVREIDALGGQMALTADATFLQMRLLNSGKGPAVQALRAQIDKRAYAWAMRLVLERTPNLDLKQAMVQEIVVEDGRVRGIVTATGIFYGAKAVVLSTGTYLHGRTIIGEVQRSSGPGGLAPAVGLTESLKRLGFEVGRFKTGTPPRVDGRTVDFSRMVRQDGDPEPHRFSFMSPLDHREQLPCWLTHTTPASHELIRRNLHRAPMFTGVIEGRGPRYCPSVEDKVVRFADKESHQVFLEPESRESHEMYVLGLSTSLPEEVQIELVRTVPGMEEAELMRPGYAIEYDYIVSTQLKPSLETKLVRGLFCGGQINGTSGYEEAAAQGLIAGINAACYVEGREPLVISRSEGYIGVLIDDLVTKGSPEPYRMLTSRAEFRMMLRQDNAHLRLTEKGREYGLVDDARWEVFVALRDGIEAERERLARTVVGPAPEVQRVLERLGSAPLKAGVTLEQLLRRPEVRYEHLVEMGLGRPDLDEAIWREVETQVKYAGYIAKEQQQVDRMRRMEARRIPPTLDYQALTGLSMEAREKLSRIRPETLGQASRISGVSPADVAVLMVHLDRLARARDRAEEA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG20_KLULA
Sequence: MQINFEPMPNSVTHLENNSPSRLKNNKTVEEHKEHEPDLQTQSEMRRESNGSPKDTAVTNQNGDQPHENVIHTQIIKKDNPFFNYMQDNVDGSDENGKNDDDDENAKNAGSDDNEDQLLQPNRRKNSKERRRSSVATSKDSSPDVPYNTLNHNASGMTKEGKKRAQILEASKVSEGQGRTYIAYAIKYGDSIVKRRYSDFESLRKVLVKLFPISLIPPIPEKQSLKSYGKAMTYSKSSYLLPTESGDSVDLSLSVINGPVTTNDEKLIRHRIRMLTSFLNRLLKNQEITKTSIVYDFLDPNNKNWNDLITSSLTISSLPKSVLQCNPIDPTNTTKAHSYLPVPSSSTQLLASKDNHSASDADEFTKIEAEFKNYEQLIHSGLYKYSRATTKEVNYLREDLKGISSEFAQLSTDETKNESGLAELLSHSSDAYGTLQEILETLVGNLHYNINEPLSECAHMATAVRDLIHYRRLKLIQKDILERTILYKRGQLIKFQQQENDHKQIDNMVKEELGTNGAVNLENPAGPQSYSGKFINKFTQLAIIIKDSVSYQEQDPAAAARSLEKELIQLDETLKVATSDLVVISETLKNTELPNFIKERDEELTQIFKNYAKYMKENATRNLEIWKELHNRIQEA
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Functions in protein retrieval from the endocytic pathway (By similarity).
What are the official names of this protein?
Autophagy-related protein 20.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: RECX_AGRFC
Sequence: MEFDGEAQAVEPTSRMLSWARNSALYRLQQRMMTEKQLRDAIMRKAREKFEDIGPAQVKALGEFAVTFAYGIKALDDTAYAEITVRSGQRSGKSKRGLAQKLQIKGVARETATAALQETNDLVAAVIFARKRAFGPYRRVEPDEKRKAKEFSAFARNGFSFEIGAKVMAMTTEEAEDILSDAPL
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_CERS1
Sequence: MANVVVVGAQWGDEGKGKIVDWLSERADVIARFQGGHNAGHTLVIDGKVYKLSLLPSGIVRPGKLSVIGNGVVLDPWHLVQEIAKLRADGVEISPESLMIAENAVLILPLHGELDRARESQNSVAKIGTTGRGIGPAYEDKVGRRAIRVADLADEATLALRVDRLMVHHDALRRGLGIEPVDREALLTQLREIAPQVLPYAKPVWKVMNEMRKAGKRILFEGAQGALLDIDFGTYPYVTSSNVIAGQAATGTGIGPGAIGFVLGIVKAYTTRVGEGPFPAELQDADGERLGERGREFGTVTGRKRRCGWFDAVLVRQTCATSGVSGIALTKLDVLDGFETLKICVGYELDGERLDHLPIAADQQARCTPIFEELEGWSESTAGARSWADLPGAAVKYVRRIEELIQCPVALLSTSPERDDTILVTDPFED
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCAT_DROME
Sequence: MTTSTIKPTGGDEVPPAGVVGNVADVGVAASLTKRDSEEDTWASKGYNYINPFVHRIEIDSHIEVAKIYVLTVLLLPIRVVGCVLSLISAWMFACIGLYGMTLDDLKAKPLTGWRKQMQYMTACGMRMVYTFGSFHYVTMKGRAATAKEAPILVVAPHSSYVDSILVVASGPPSIVAKRETADIPLLGKIINYAQPIYVQREDPNSRQNTIRDIVDRARSTDDWPQVVIFAEGTCTNRTALIKFKPGAFYPGVPVQPVLLKYPNKYDTFTWTWDGPGVLRLLWLTMTQFYNRCEIEYLPVYTPSEDEVADANLYANNVREVMAKALGVPTSDYSFEDVIVMSRARDMKIPFPGDIVEIERTIEKLGLNESQRDAELCKGFLRLSNTDRLDIITFGELLQVDLKNTDLHKLFALLDHRRSGTVSLKSFLLCSLFCKLKNSDLLTFLRALIHLYSESSQQIDRESFVRLMRHAGGKLNEQKAQALFYALDTDNLGYVSFDSFVELTEKQKSSYKFLYHKSEHIRRPKAVVTTAEN
What is the function of this protein?
Acetyltransferase which mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (By similarity).  Has a calcium-independent activity (By similarity).  Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (By similarity).  Involved in the regulation of lipid droplet number and size (PubMed:25491198).
What are the official names of this protein?
Lysophosphatidylcholine acyltransferase, 1-acylglycerophosphocholine O-acyltransferase, Acyltransferase-like 2.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Lipid droplet.
Protein: CYAY_RICPU
Sequence: MNNSEFSKIAETTIAYIAEKIEEQDKEASIDVDLQGDILNLDTDKGVYVINKQSAAKEIWLSSPVSGPYHFCYEQGKWTNRAGLELMAILTEELNIKFDTRPT
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: RSMI_RICPR
Sequence: MILKSGLYIVSTPIGNFEDITLRAISTLKNSDIILCEDTRISQKLLAKHYIHTKLQIYNDHSDYKDREYIISLIKAGNVVSLISDAGTPLISDPGYKLVRDLRNLNYYIEVVPGVSSPITALTLSSLPTDRFLFSGFLPKTIESKKKIFAELVNLKATLIFFDTASRLINTLLLAKEIFGNREICVARELTKIYQETKTGDIDEIIEFYKNNILKGEIVLLISGNVQVQNKQINLEKFIEFCLSKNLSSKTIIELAYDKFKDVYSKKEIYSVVHKKKFTA
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET_CANLF
Sequence: MKAPAVLAPGILVLLFTLVQKSYGECKEALVKSEMNVNMKYQLPNFTAETPIQNVVLHKHHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCSPCQDCSHKANLSGGVWEDNINMALLVDTYYDDQLISCGSVHRGTCQRHILPPSNIADIQSEVHCMYSSQADEEPSQCPDCVVSALGTKVLISEKDRFINFFVGNTINSSDHPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECILTEKRRKRSTREEVFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARNDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGLSTPHVNFRLDSHPVSPEAIVEHPLNQNGYTLVVTGKKITRIPLNGLGCEHFQSCSQCLSAPPFVQCGWCHDRCVHLEECPTGAWTQEVCLPAIYEVFPTSAPLEGGTVLTVCGWDFGFRRNNKFDLKKTKVFLGNESCTLTLSESTTNMLKCTVGPAVNEHFNISIIISNGRGTAQYSTFSYVDPIITSISPSYGPKNGGTLLTLTGKYLNSGNSRHISMGGKTCTLKSVSDSILECYTPAQATATEFPIKLKIDLANREMNSFSYQEDPIVYAIHPTKSFISGGSTITAVGKNLNSVSVLRMVIDVHETRRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNPVFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCETIYSDSKAVLCKVPNDLLKLNNELNIEWKQAVSSTVLGKVIVQPDQNFTGLIAGVISISTIVLLLLGLFLWLKRKKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDLSPMLTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNIDGEGDT
What is the function of this protein?
(Microbial infection) Acts as a receptor for Listeria monocytogenes internalin InlB, mediating entry of the pathogen into cells.
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.