PharMolix/UniProtQA huggingface dataset:
Protein: STCE_ECO57
Sequence: MNTKMNERWRTPMKLKYLSCTILAPLAIGVFSATAADNNSAIYFNTSQPINDLQGSLAAEVKFAQSQILPAHPKEGDSQPHLTSLRKSLLLVRPVKADDKTPVQVEARDDNNKILGTLTLYPPSSLPDTIYHLDGVPEGGIDFTPHNGTKKIINTVAEVNKLSDASGSSIHSHLTNNALVEIHTANGRWVRDIYLPQGPDLEGKMVRFVSSAGYSSTVFYGDRKVTLSVGNTLLFKYVNGQWFRSGELENNRITYAQHIWSAELPAHWIVPGLNLVIKQGNLSGRLNDIKIGAPGELLLHTIDIGMLTTPRDRFDFAKDKEAHREYFQTIPVSRMIVNNYAPLHLKEVMLPTGELLTDMDPGNGGWHSGTMRQRIGKELVSHGIDNANYGLNSTAGLGENSHPYVVAQLAAHNSRGNYANGIQVHGGSGGGGIVTLDSTLGNEFSHEVGHNYGLGHYVDGFKGSVHRSAENNNSTWGWDGDKKRFIPNFYPSQTNEKSCLNNQCQEPFDGHKFGFDAMAGGSPFSAANRFTMYTPNSSAIIQRFFENKAVFDSRSSTGFSKWNADTQEMEPYEHTIDRAEQITASVNELSESKMAELMAEYAVVKVHMWNGNWTRNIYIPTASADNRGSILTINHEAGYNSYLFINGDEKVVSQGYKKSFVSDGQFWKERDVVDTREARKPEQFGVPVTTLVGYYDPEGTLSSYIYPAMYGAYGFTYSDDSQNLSDNDCQLQVDTKEGQLRFRLANHRANNTVMNKFHINVPTESQPTQATLVCNNKILDTKSLTPAPEGLTYTVNGQALPAKENEGCIVSVNSGKRYCLPVGQRSGYSLPDWIVGQEVYVDSGAKAKVLLSDWDNLSYNRIGEFVGNVNPADMKKVKAWNGQYLDFSKPRSMRVVYK
What is the function of this protein?
Virulence factor that contributes to intimate adherence of enterohemorrhagic E. coli (EHEC) O157:H7 to host cells.  Is able to cleave the secreted human mucin 7 (MUC7) and the glycoprotein 340 (DMBT1/GP340).  Also cleaves human C1 inhibitor (SERPING1), a regulator of multiple inflammatory pathways, and binds and localizes it to bacterial and host cell surfaces, protecting them from complement-mediated lysis.  Therefore, the current model proposes two roles for StcE during infection: it acts first as a mucinase, allowing passage of EHEC through the oral cavity by cleaving the salivary glycoproteins that are responsible for bacterial aggregation.  Similarly, in the colon, StcE cleaves the glycoproteins that protect the intestinal epithelial surface, allowing EHEC to come into close contact with host cell membranes.  Secondly, it acts as an anti-inflammatory agent by localizing SERPING1 to cell membranes.
What are the official names of this protein?
Metalloprotease StcE, Mucinase, Neutral zinc metalloprotease StcE, Secreted protease of C1 esterase inhibitor from EHEC.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the etp type II secretion pathway.
Protein: METK_FRATH
Sequence: MSKNYLFTSESVSEGHPDKLADQISDAILDEILKQDKNARVACETLVKTGMALVAGEITTSAWVDIEELVRNVITETGYDNASKGIDGRTCSVINAIGKQSRDIAQGVDRGSLEDLGAGDQGLMFGFATNETPTLMPSAIYYSHLLMRKQAELRKSGKLAWLRPDAKAQVTLAYENDKPKFIDTIVLSTQHNESISQKELHDAVIEEIVKKVIPNELITKDTKYHINPTGVFLIGGPQGDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSGAYMGRYIAKNIVAAGLADKCEVQVAYAIGVAKPVSLMVNTFGTGKITDNQIEKLVAEVFDLRVGKIIENLDLLRPIYRKTSNYGHFGRELPEFTWEKIDKADILKSAARI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBL1_SCHPO
Sequence: MLIKVKTLTGKEIELDIDPNDKVSRIKERVEEKEGIPPSQQRLIYAGKQMADDKNAESYHLEGGSVLHLVLALRGGSC
What are the official names of this protein?
Ubiquitin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
Protein: RS18_CAPHI
Sequence: MSLVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVGVSKKK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_PSEE4
Sequence: MSRVAKNPVKLPAGVEVKFAGQQLSVKGAKGTLELNVHSSVEVTEEAGELRFSARNGDQQARAMAGTTRALVNNMVQGVSQGFERKLQLVGVGYKAQAKGTVLNLALGFSHPVDYELPAGITAETPSQTDILIKGIDKQLVGQVAAEVRGFRPPEPYKGKGVRYADEVVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RS19_ACTPJ
Sequence: MPRSLKKGPFLDLHLLKKVEKAVESGDKKPIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSDEMIGHKLGEFAPTRTYRGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: YS41_CAEEL
Sequence: MALQQGGDYYGTSNVVAQKFYRGQDNQRPAGCVLPSIDCLLHDKTTYSGNRDYNNENSKGFAEANGHEIFDPQGFKETVSICDRRALEAPPHQNYPVQNLNGMGGAFYNSDSNGQQFVQSYDNLPFGKIKISHASDQKSRPKPTKPRASRKRAAIAQSKKKRSGGDLTLDGLVQLLGEIVDPVKLQAEIDEQKSRQSTSQPDKEIVQSSQYSHNGFIQHASPQIYNYNYQGYTMVQAEAYQPQYQEHVQYTQYSQGPINQTNIQEVQSEDSEGIYEYFVDQPNYSNQGTNQGTCQGFIQINGNFQENVQIVSQDNVQGSSQGYIQEYYQYE
What are the official names of this protein?
Uncharacterized protein ZK177.1.
Protein: GUAA_AGRFC
Sequence: MTQIAHPDSILIIDFGSQVTQLIARRIREAGVYCEIHPFQNAAEAFEKLQPKGVIFSGGPASVTAEGSPRAPQAVFDSKVPILGICYGQQTLCTQLGGVVEGGHAAEFGRADIDIKKASPLFEGFWEQGKSYPVWMSHGDRVTKLPEGFEVIATSENAPFAIAADEKRHYYTTMFHPEVVHTPDGGKLLSNFVHKIVGLKSDWTMAAYRAEMIRKIREQVGTGRVLCALSGGVDSSVAAILIHEAIGDQLTCVYVDHGLMRLGESEQVVGMFRDHYNIPLVHVDAADLFLGELSGVSDPEVKRKTIGRLFIEVFEAEAAKIAADGKGAPKFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRALGRELGLPESFIGRHPFPGPGLAIRCPGAITREKLDILRKADAIYLDEIRKAGLYDTIWQAFAVLLPVQTVGVMGDYRTYDFVCALRAVTSVDGMTADFYPYDMNFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL34_MYCA9
Sequence: MAKGKRTFQPNNRRRARTHGFRLRMRTRAGRAIIAGRRRKGRRELTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CAPSP_ASFP4
Sequence: MAANIIATRATPKMASKKEHQYCLLDSQEKRDGHYPFSFELKPYGQTGANIIGVQGSLTHVIKMTVFPFMIPFPLQKIHIDDFIGGRVYLFFKELDVQAISDVNGMQYHFEFKVVPVSSNQVELLPVNNKYKFTYAIPEVQYLTPIFYDLSGPLNFPLDTLSVHVDSLTKHIQLPIQNHNLTTGDRVFISGYKHLQTIELCKNNKIFIKCIPPLSSEKIKLYIPKNRIRIPLYFKSLKNV
What is the function of this protein?
Forms the penton at the fivefold vertices of the icosahedral capsid (By similarity).  Together with the minor capsid proteins (p17, p49, and M1249L), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid (By similarity).
What are the official names of this protein?
Penton protein H240R, pH240R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H240R family.
What are the subcellular locations of this protein?
Virion.
Protein: KDM4C_HUMAN
Sequence: MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAVKLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSISSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLEPGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEVLSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSSNEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDWPYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVMAVTSQTFYEVMFDDGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGSNIAHMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGERKRQRVLSSRFKNEYVADPVYRTFLKSSFQKKCQKRQ
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code.  Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'.  Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues.  Demethylation of Lys residue generates formaldehyde and succinate.
What are the official names of this protein?
Lysine-specific demethylase 4C, Gene amplified in squamous cell carcinoma 1 protein, GASC-1 protein, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, [histone H3]-trimethyl-L-lysine(9) demethylase 4C.
What is the protein family that this protein belongs to?
Belongs to the JHDM3 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUD22_ARATH
Sequence: MKSGASAASPTAKSFNFGSSRLLALAQQLRVYKPPLSSSFDEREELLAYKESTRKSITHVGFQESMAPVRFRPKKAAVLICLFEGDDGDLRVILTKRSSTLSTHSGEVSLPGGKAEEHDKDDGITATREAEEEIGLDPSLVDVVAFLEPFLSQHLLRVIPVVGILWDRKAFNPTPNPAEVEAVLDAPFEMFLKDENRRSEEFDWMGEKHLVHFFDYKTGDSDYVIWGLTARILIRAATVVYQRPPAFIEQKPNLKYSKMNQATRLYGWLKPLANLHESCENGRLLGHVPAYCLRYLVGISSR
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Nudix hydrolase 22, chloroplastic, AtNUDT22.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOB_TRIEI
Sequence: MTYQKLNVNTYSNLQIFNMPDLIEIQRASFRWFLEYGLIEELDSYSPITDYTGKLELHFIAKNYKLKQPKYSVEESKRRDSSYAVQMYVPTRLINKETGEIKEQEVFIGDLPLMTDRGTFIINGAERVIVNQIVRSPGVYYKSETDKSGRRTYNASLIPNRGAWLKFETDKNDLVWVRIDKTRKLSAQVLLKALGLGDSEIFDSLRHPDYFQKTIEKEGQYGEEEALLELYRKLRPGEPPTIAGGEQLLHSRFFDQKRYDLGQVGRYKLNNKLRLNLPNTVRVLTKEDILASIDYLINLEYDIGQTDDIDHLGNRRVRSVGELLQNQIRVGLNRLERIIRERMTVSESETLTPTSLVNPKPLVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRISALGPGGLTRERAGFAVRDIHPSHYGRICPIETPEGPNAGLIGSLANHAKVNSYGFIETPYYPVENGRVLRDRTPIYMTADAEDDLRVAPGDIMTDAEGKILGDVVPVRYRQDFTTTNPQQVDYVAVSPVQVVSVATSLIPFLEHDDANRALMGSNMQRQAVPLLNPDRPLVGTGLEPQAARDSGMVVVTRTDGEVSYVDSTKISVIDKEGNQADYPLCKYQRSNQDTCLNQRPLVFEGDQVVAGQVLADGSSTEGAELALGQNVLVAYMPWEGYNYEDAILISERLVYDDVYTSIHIEKFEIEARQTKLGPEEITREIPNVGEDGLRNLDEQGIIRVGAWVQSGDILVGKVTPKGESDQPPEEKLLRAIFGEKARDVRDNSLRVPNGEKGRIVDVRVFTREKGDELPPGANMVVRVYVAQKRKIQVGDKVAGRHGNKGIISRILPIEDMPYLPDGTPIDVVLNPLGVPSRMNVGQIFECLLGWAGEILSVRFKCVPFDEMHGPEKSRETVHLMLKLARDNSGKDWVFDEKHPGKIWVFDGRTGERFDRPVTVGIAYMLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRFGEMEVWALEAFGAAYTLQELLTVKSDDMQGRNEALNAIVKGKAIPRPGTPESFKVLMRELQSLCLDIAAHKVETVDDGTTQDVEVDLMADLPGKRTPSRPIYESLSTEGNQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: OLF9_MOUSE
Sequence: MGDDNDTDITEFILLGFSGYGFLQGHLFWGVLCIYVVTLLGNSLIVLLTLADSALHSPMYFFLRHFSVVEILYTTTIVPRMLADLRSSCPTIPLASCFTQLYFFALFGIAECCLLTAMAYDRYAAICCPLHYTTLMSQGTYTGLVGASYLAGVISGTTHSIFIFTLPFRGAKTIHHFLCDILPVLRLATASTFWGEVGNLFVTITFIFVPFLLIVASYACILVTILGVATSQGRQKLFSTCSSHLFVVILFFGTATVAYMRPQADSFGNTDQILTLVYTVVTPMCNPFVYSLRNKEVTGAMRRLMKRYLWGP
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 9, Odorant receptor M25, Olfactory receptor 269-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCRD_METFE
Sequence: MDVEIFPHRLLSAETTEKLLNKLGEIEGIKRMIIQGQRLPAGEHPDRRVINVKGQDIELKVKTGRIFVEIEDKKTMEKIKEVCDEVFPFKYELIPGTFFRRQKTVTDAIKFGKDVDKLPTELVGMTDTVLD
What are the official names of this protein?
Methyl-coenzyme M reductase operon protein D.
Protein: RECO_MESFL
Sequence: MSEVKIRGIVLDSLNYEENDKIITVYSDEFGKLSFIALGANKASSKNNYSLNVFSESDFEIFKSRKTQSISKLKTGILVRNNFKIAKSYNNYLFASIISSVILQEELFYNKDFKLFDMLREAIRNINDEVNPFSNMVWFLFYSLKNFGGYWELNKCYRCNKASKIYRKFDLQHYGLVCPNCINENEEEHDYEFIKYLQRMDNNTFFTIQKFPINVSFEIIISKLLFSYYLNEIGIYSYPMNEILKKEVYKDDTFWEYTHKVLTKNSI
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TSAD_CAMJ8
Sequence: MKNLILAIESSCDDSSIAIIDKNTLECKFHKKISQELDHSIYGGVVPELAARLHSEALPKILKQCKEHFKNLCAIAVTNEPGLSVSLLSGISMAKTLASALNLPLIPINHLKGHIYSLFLEEKISLDMGILLVSGGHTMVLYLKDDANLELLASTNDDSFGESFDKVAKMMNLGYPGGVIIENLAKNAKLKNISFNIPLKHSKELAYSFSGLKNAVRLEILKHENLSDEIKAEIAYAFENTACDHIMDKLEKIFNLYKFKNFGVVGGASANLHLRSRLQNLCQKYNANLKLAPLKFCSDNALMIARAAVDAYKKKEFVSIEEDILSPKNKNFSRI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K2C71_BOVIN
Sequence: MSRQFTCKSGAAAKGGFSGCSAVLSGGSTSSYRAGGKGLSGGFGSRSLYNLGGVRSISFNVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPMCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVRDVVEDYKKRYEEEINRRTAAENEFVLLKKDVDAAYANKVELQAKVDSMDQEIKFFKCLYEAEIAQIQSHISDMSVILSMDNNRDLNLDSIIDEVRAQYEDIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEAALHQSKEELARMMREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGSGGYGFRPSSVSGGYVANSGSCISGVCSVRGGESRSRSSTTDYKDALGKGSSLSAPSKKASR
What is the function of this protein?
Plays a central role in hair formation.  Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle.
What are the official names of this protein?
Keratin, type II cytoskeletal 71, Cytokeratin-71, CK-71, Keratin-71, K71, Type II inner root sheath-specific keratin-K6irs1, Type-II keratin Kb34.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYE2_RUEST
Sequence: MTTTRFAPSPTGYIHVGNLRTALMNYLIARKAGGTFILRIDDTDPERSKEEYVDAIKQDLEWLGITWDKVERQSERLDRYAEAADKLREIGRFYEAFETPTELDLKRKKQLNMGKPPVYDRAALALSDAEKESLRAERGNGVWRFKLDQERIEWTDGILGDISIDAASVSDPVLIRGDGQVLYTIASVVDDTDMGVTHVVRGSDHVTNTATQIQIMAALGHGHPEFAHHSLLTGPQGEALSKRLGTLALRDLREAGVKPMALLSLMARLGSSDPVELRTDMAELVDGFDINRFGSAPTKFDAEDLYPLTARYLQTLPVATVKSELDAIGVPADTQEAFWAVAKENITTLKDLEGWWILCRDGAEPLIADEDKEFIAEAMTLLPEGPYDSESWGKWTAAVKEKTGRKGKGLFMPLRKAVTGMERGPDMSALLALMQTVRARG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGUA_ASPTU
Sequence: MRGSNLFQLTLALLLSLVAAEDGYNGWLRYAPVSCDLHCRQALPSHIVLLNSTKGSPIETAGRELKAGFQSILSTNLTFHPFQCDSSASILVATLDEYRQKCRDINLPELDPDGFWLQSEGDTVRILGNNARGALYGAYEYLAMVAQRNFSRVAYTTNPHAPIRWVNQWDNMDGSIERGYGGASIFFKDGTVVEDMAPVEQYARLLASIRINAIVVNNVNANATLLLPENMKGLGRIADACRPYGVQIGISLNFASPESLGGLETYDPLDPGVIAWWQNITDSLYTYVPDMAGYLVKADSEGQPGPDTYNRTLSQGANLFARALQPHGGVLMYRAFVYNDNLNESDWKADRAKAAVEYFKDLDGQFYENVVVQIKYGPIDFQVREPTSPLFANLYQTNTAIELEVSQEYLGQQCHLVYLPPLWKTVLDFDLRVDHKPSMVRDILSGQRFNRTLGGWAAVVNVGTNRTWLGSHLAMSNLYAYGRLAWSPTDDSEQILKDWTRLTFGQNRQVIDTIADMPMTSWPAYENYTGNLGIQTLTDILYTHYGPNPATQDNNGWGQWTRADHNSVGMDRTISNGTGYTGQYPEEVARLYESLETTPDDLVLWFHHVPWTHRLHSGLTVIQHFYNAHYAGSEAAHGFIRQWESLKGLIDRERYEAMRSRLVYQAGHSIVWRDAINNFYYNMTGIPDVAGRVGHHPWRIEAESMRLDGYQTYTVSPFEAASNTTAIITTSNSTTGTARTTIKAPSGVYDIGVNYYDLYGGQSKWTLSVGDKVVGQWLGDMEHQSLGHTPSIYLDGHSATRITFHGVVVRQGDQLKIVGEANGVEPAPVDYVVLLPPGVVD
What is the function of this protein?
Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Releases 4-O-methylglucuronic acid from xylan.
What are the official names of this protein?
Alpha-glucuronidase A, Alpha-glucosiduronase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 67 family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIE_ECOLI
Sequence: MYQPDFPPVPFRSGLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYPTVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RS11_LACDB
Sequence: MPAKKTAHKRRVKKHVESGVAHIHSTFNNTLVMITDVQGNAVAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAIDQGMKHIEVSVKGPGSGRESAIRALQAAGLEITSIRDVTPVPHNGSRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: GLYA_JANMA
Sequence: MFSKDQTLAKTDAELWSAIQKENTRQQEHIELIASENYTSPAVMEAQGTQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRLKQLYGADAANVQPNSGSQANQGVFLAVLKPGDTIMGMSLAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYDAMERLAREHKPKLIIAGASAYALRIDFERFAKIAKEIGAYFMVDMAHYAGLIAAGEYPNPVPFADFVTSTTHKSLRGPRGGFILMKAEHEKIINSAIFPGLQGGPLMHVIAGKAVAFKEALAPEFKTYQQQVVKNADALAKALIARGLRIVSNRTESHVMLVDLRAKKITGKDAENLLGSAHITCNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFKEAEATKVGNLIADVLENPNDAATIERVKAEVKKLTDAFPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S2538_SCLS1
Sequence: MSNGGNAGKKSSSYFHFTAGLGSGILSAVLLQPADLLKTRLQQSNHASLLTTIRELSQSPNTIRSFWRGTVPSALRTGFGSAIYFTSLNALRQNVARSNLLRTIGVVDAKNGPVHSSSLPKLSNLANLTTGAVARAGAGFVLMPMTIIKVRYESNLYAYKSIMGAGRDIFLTEGFRGFFSGFGATAIRDAPYAGLYVLFYEQLKKRLSHIVHSVPQAEELVENLGVRKNMKGSTSASINFGSGVLAAGLATAITNPFDAIKTRIQLQPKKYTNLVMAGRKMVGEEGVKSLFDGLGLRMGRKAVSSALAWTIYEELIRRAELAWKGEEVIV
What is the function of this protein?
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix.  Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial glycine transporter, Solute carrier family 25 member 38 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURT_STAAN
Sequence: MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDVLRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
What is the function of this protein?
The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide (PubMed:22291598, PubMed:30154570).  The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue (PubMed:22291598).
What are the official names of this protein?
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurT subfamily.
Protein: MURB_SYNWW
Sequence: MYSEIFDFLPPERIKINEPMKEHSSFKIGGPVDLMVLPESIEEIQRITHYCRKKDIPCFVFGLGSNILVRDKGIRGVAIKVGNNLKNISICNDTIFAEAGVRLAELSQAAADYSLSGLEFAEGIPGSLGGAVVMNAGAYGGEMKDVLKEVRAITPDGNLSSFKPEEMKLRYRGSIFQEEELIVVSALMQLHKERAEDIRARMQDFAKRRREKQPLEYPSAGSTFRRPAGFFVGPMIEEMGLKGFKVGGAEVSRKHAGFIINSGNATANEVLELIAIVKAKAKEHYGIELETEVKVVGEE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYW_VIBCH
Sequence: MSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPQALHEATLDALAICLAVGVDPKKSTLFVQSHVPEHAQLGWVLNCYTQMGELSRMTQFKDKSARYANDVNAGLFGYPVLMAADILLYGAHQVPVGSDQKQHLELARDIATRFNNIYSPEQPIFTIPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLLEDPKSIIKKINKAQTDAETPPRIAYDVENKAGIANLMGLYSAATGKTFAEIEAQYAGVEMYGPFKKDVGEAVVAMLEPVQAEYQRIRNDREYLNSVMRDGAEKASAKALQTLKKVYAAVGFVARP
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.