PharMolix/UniProtQA huggingface dataset:
Protein: KNX11_MAIZE
Sequence: ADRELKEMLLKKYSGCLSRLRSEFLKKRKKGKLPKDARSALMDWWNTHYRWPYPTEEDKVRLAAATGLDPKQINNWFINQRKRHWKPS
What is the function of this protein?
Probably binds to the DNA sequence 5'-TGAC-3'.
What are the official names of this protein?
Homeobox protein knotted-1-like 11.
What is the protein family that this protein belongs to?
Belongs to the TALE/KNOX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DBP5_BOTFB
Sequence: MAESKSTSWADEVASPTIEKNEGNPLEEAQLDGATEPLGGGTLQDGQYEVEVKLSDIQGDETSPLYSVETFEQLGIDASILKGLYAMNFKKPSKIQEKALPLLLRNPPTNMIAQSQSGTGKTAAFVITILSRLDFSKPTTPQALCLAPSRELARQIEGVIRSIGQFVDGLTVQAAIPGAVERNAKVNAMVVVGTPGTVMDLIKRRSIDASQMKILCLDEADNMLDQQGLGDQCMRVKSMIRVEQILLFSATFPDEVYGFAQDFSPRANEIKLKRDELTVSGIKQMFMDCPNEVGKYEILVKLYGLMTIGSSIIFVKRRDTASNIAERLTKEGHKVAAVHGAFEGSERDQVLEDFRQGKAKVLITTNVLARGIDVQSVSMVINYDVPMKGRSDSDPPPETYLHRIGRTGRFGRVGVSISFVFDRKSYDALNQIANHYNIDLIKLNQDDWDETEEIVKKVIKSSRAGTNLQS
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: HIS1_BUCA5
Sequence: MFENNRVRIAMQKTGRLSKDSIRLLTSCGVKINLKQQKLIAFAENMPIDVMLVRDDDIPGLVMDGVVDLGIVGENVLEEELLKRKSQKSECSYITLRRLDFGVCRLSLALPVNTIYTNITCLKNIRIATSYPHLLKKYLDEKNISFKSCMLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVQVVYHSHACLICKTGNINSIKKEFINKLMTRIKGVIKARESKYIMLHAPIKQLEAVISLLHGAERPTILKLAGDDNRVAMHMVSSETLFWETMEKLKLLGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_ECOL5
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RHO2_EHRCR
Sequence: MLDLSELKKKTIEDLLKIAEDLGVVSNGRMLKQEIIFHLMKKVVSDGGAAIGGGVVEILSDGFGFLRSPEANYAASGDDVYISAGQIKKFNLRTGDIVSGEIRAPSEKERYFTLVKAHSINFTDMAKLQRYVHFDDLIPLYPEERILLECNDPISVSKKDISMRVIDIVAPLGKGQRALIVAPPRAGKTIILQQIAHSISVNHPDIELIVLLIGERPEEVTDMCRSVKGEVVSSTFDEPGYRHVQLAEIVIEKAKRMVEHKKNVVILLDSITRLARAYNSVIPSSGKVLTGGVDSNALQRPKRFFGAARNIENGGSLTIIATALIETGSKMDEVIFEEFKGTGNCEIILDRKISDKRVYPAIDISKSGTRKEDMLIDSVCLKKVWLLRRLLSSMGSVEAMEFLRDKLLITKDNNEFFDMMNS
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho 2, ATP-dependent helicase Rho 2.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: MAGA2_HUMAN
Sequence: MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE
What is the function of this protein?
Reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites.  Also represses p73/TP73 activity.  Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases.  In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination by TRIM28 potentially in presence of Ubl-conjugating enzyme UBE2H.  Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.  May play a role in embryonal development and tumor transformation or aspects of tumor progression.  In vitro promotes cell viability in melanoma cell lines.  Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.  Negatively regulates acetylation and sumoylation of PML and represses PML-induced p53/TP53 acetylation and activation.
What are the official names of this protein?
Melanoma-associated antigen 2, Cancer/testis antigen 1.2, CT1.2, MAGE-2 antigen.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.
Protein: RL33_SYNJA
Sequence: MAKAKGARIIITLECTECRTNVNKRSPGVNRYTTTKNRRNTTARLELKKFCPKCNRHTVHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: VATF_PYRHO
Sequence: MKVVIMGDSDTVVGFRLAGIHEAYEFDLSELSIERARNKLKELVERDDVGIILITERLAQKIGELPQVNLPIILQIPDKFGSIYGEELLREIVRRAVGIEVKR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: LEUC_PARMW
Sequence: MSSGTLYDKVWDLHRVAELPGGSTQLFVGLHLIHEVTSPQAFAALRDKGLSVRCPERTVATVDHIVPTTSQSRPFADSLAEEMLSTLERNCADHGITLNGIGSGRQGIVHVIAPELGLTQPGMTVACGDSHTSTHGAFGAIAFGIGTSQVRDVLASQSLAMSKLKVRRIQVNGRLSDGVSAKDLILHVIRTLGVKGGVGFAYEFAGPAVEALSMEERMTLCNMAIEGGARCGYVNPDQVTFDYLSGRAGAPSGAAWDRAVSWWRGLASDPDAVVDDEVVFDAASIAPTVTWGITPGQGLGIDECIPQLEQLEPGERPIAEEAYRYMDLQPGTAIAGVPVDVCFIGSCTNGRLSDLRAAAAVARGRHVADGIKAFVVPGSEQVAKAAEAEGLDRVFQDAGFEWREPGCSMCLAMNPDRLEGRQISASSSNRNFKGRQGSASGRTLLMSPAMVAAAAVHGQVTDVRTLSLQSAV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: USPB_ECOL6
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHIT_AVESA
Sequence: VSSVISSSLFEKMLLHRGFYTYDAFIAAAKSFPAFATTGSTDVRKREVAAFLAQTSHETTGGWPTAPDGPYELGSTSDYFGRGPIQISYNYNYGAAGKAIGVDLLRNPDLVTSDNTVEFKTALWFWMTPQSPKPSSHDVITGRWSPSSTDKAAGRVPGYGVLTNIIDGGVECGKGQESHVADRIGYYKDNLDCYNQKPFA
What is the function of this protein?
This protein functions as a defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Endochitinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: Y167_BUCAP
Sequence: MKSFSNIDFSKLSLIDSIIATSQIIREDFPTKFVISDLYNKVKEAKFYISSEIEPNLKLKKLLKLFYKTWNFGAASGIYKLSDVLWIDNVLKTRQGTAVSLGILFLHIAQELKLPLNPVVFPTQLILRADWINKKKWLINPFNGEMLDQHTLEVWLKGNISPTAELYEHDLYKAESITVIRKMLDILKSALMEEKKMELALNVSNLLLQINPNDPYEIRDRGLIYANLECNHVALTDLIYFVEHCPEDPISEIIKVQIHAIEQKKMILH
What are the official names of this protein?
UPF0162 protein BUsg_167.
What is the protein family that this protein belongs to?
Belongs to the UPF0162 family.
Protein: 6HN3M_PSEPK
Sequence: MRGRQKIAIVGAGLGGAAAATLLQQAGFDVEVFEQAPAFTRLGAGIHIGPNVMKIFRRMGLEQKLELMGSHPDFWFSRDGNTGDYLSRIPLGEFARREYGAAYITIHRGDLHALQIEAIQPGTVHFGKRLEKIVDEGDQVRLDFADGTHTVADIVIGADGIHSKIREELLGAEAPIYSGWVAHRALIRGVNLAQHADVFEPCVKWWSEDRHMMVYYTTGKRDEYYFVTGVPHEAWDFQGAFVDSSQEEMRAAFEGYHPTVQKLIDATESITKWPLRNRNPLPLWSRGRLVLLGDACHPMKPHMAQGACMAIEDAAMLTRCLQETGLSDHRTAFALYEANRKERASQVQSVSNANTWLYSQEDPAWVYGYDLYGQQLESGEAA
What is the function of this protein?
Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway.
What are the official names of this protein?
6-hydroxynicotinate 3-monooxygenase, 6-HNA monooxygenase, Nicotinate degradation protein C.
What is the protein family that this protein belongs to?
Belongs to the 6-hydroxynicotinate 3-monooxygenase family.
Protein: RBFA_TREDE
Sequence: MSEFRLARLGEQIREEISALICSGKIKDPRVSSLLSINRVIVSGDLAYAKVYVSSFLDEHKTKQGVRGLENASGFIRTSLAKKLHVRQCPELTFIFDKSIKEGIDMVNKLESLEYFTDPDEDEGTAGSSEAD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_THET8
Sequence: MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: Y1612_HALH5
Sequence: MRGARCHNRRCYVYGHLYDSGLGYPALIADEKGGKVVGELYEINEQHLVSLDELEDYAPDRNHNLYERVLHTLEDGSHCYLYVVTPDSPLVRTLIPSGDWLDWTENKKSTE
What is the function of this protein?
Putative gamma-glutamylcyclotransferase.
What are the official names of this protein?
Putative gamma-glutamylcyclotransferase BH1612.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: ROCA_GEOKA
Sequence: MVQPYRHEPLTDFTVEANREAFLAALKKVESELGRDYPLVIGGERVMTEDKIISINPANKTEVVGRVAKANKELAERAMKTADEAFRTWSRTSPEARADILFRAAAIVRRRKHEFSAWLVKEAGKPWREADADTAEAIDFMEYYGRQMLKLKDGIPVESRPGETNRFFYIPLGVGVVISPWNFPFAIMAGTTVASLVTGNTVLLKPASATPVVAYKFVEVLEEAGLPAGVLNYIPGSGAEVGDYLVDHPRTRFISFTGSRDVGIRIYERAAKVHPGQIWLKRVIAEMGGKDAIVVDKEADLELAAQSIVASAFGFSGQKCSACSRAIIVEDVYDQVLSRVVELTKQLNVGDPAEQATFMGPVIDQNAYNKIMEYIEIGKQEGRLMTGGEGDDAKGFFIQPTVFADVDPNARIMQEEIFGPVVAFAKARDFDHALEIANNTEYGLTGAVISRNRANLEKARHEFHVGNLYFNRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLILHMQAKTVSEMF
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: FABZ_STRP2
Sequence: MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFFNGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQLVMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBJQ_ECOLC
Sequence: MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RNC_ECO8A
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRDB_PELPD
Sequence: MKPDMTVNLAGLELRNPVMTASGTFGYGREFADYVDLEKIGAFVTKGLSLKPRPGNPTPRIVETPGGMLNAIGLQNVGIEAFIAEKVPFLARVNTPAIVNFFGSTPEEYAELAGRLDEIPQVAGLEVNISCPNVKQGGIVFGTDPACAGQVVAACRRATKKPLIVKLSPNVTDVVVMAQACADAGADALSLINTLTGMAIDLKSRKPVLANITGGLSGPAIKPVALRMVWQVSRAVQVPLIGIGGITSATDALEFILAGASAVQVGTASFITPSASQEIAQGMERWLEEHGVARVSDLVGALEC
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_TRIEI
Sequence: MSVIAGEIVEPYAAALMSLAQSKDLTDKFAEDVRSLINILDESPEFKQFVGNPVIKQEDKKAVVKRMLGEQVDPLMRNFLMLLIDKGRITFLEQIGKQYLALLRELNQTVLAEVTSTVELNENQKNTIRERVKSMTSAREVEIETKVDPSILGGVIIKIGSQIIDSSLQGQLRRIGISLKTL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RS3_STRE4
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINKELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINIIEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGADIARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NR_NARPS
Sequence: MSLEKRWSLEGTTALVTGGTKGIGHAIVEELVGFGARVYTCSRNEAELRKCLQEWENLKYDVTGSVCDVSSRTEREKLAEEVSSVFNGKLNILINNAGGYVNKPIDGFTAEDFSFLVAVNLESAFHLCQLAHPMLKASGTGSIVHISSCCAQIAIPGHSIYSSTKGAINQLTRNLACEWAKDNIRTNSIAPGAIRTPGTESFVIDKDALDREVSRVPFGRIGEPEEVASLAAFLCMPSASYITGQVICVDGGRTING
What is the function of this protein?
In the Amaryllidaceae alkaloids biosynthesic pathway, catalyzes the conversion of noroxomaritidine to oxomaritidine, a precursor of haemanthamine- and crinamine-type alkaloids, promising anticancer agents (PubMed:27252378).  Can also, to some extent, catalyze the condensation of 3,4-dihydroxybenzaldehyde (3,4-DHBA) and tyramine to produce norbelladine, and of isovanillin and tyramine to produce 4'-O-methylnorbelladine (PubMed:27252378).
What are the official names of this protein?
Noroxomaritidine/norcraugsodine reductase, NorRed.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. SDR65C subfamily.
Protein: LYS4_ASPOR
Sequence: MQSRLMPSGGPGRRWAFLRVPSTPQRRAFASTRFYFQDIFQSQLEDPSSAAVYSSLQASRAVPQTLTEKIVQKYSVGLAKDKFVKSGDYVTISPHRCMTHDNSWPVALKFMSIGATKLHDPKQIVMTLDHDVQNKSEKNLQKYRQIEDFAKHQGVEFYPAGRGIGHQVMVEEGYAWPGTLVVASDSHSNMYGGVGCLGTPIVRTDGASIWATGKTWWQIPPVAKVTLTGVLPPGVTGKDVIVALCGLFDKDDVLNHAIEFTGPEETMRSLSVDARLTIANMTTEWGALSGLFPIDNVLKGWLKGKATTAAMGLAEGPFKTLAPQHFTHPLLEQLFANPLTADKGAKYAKELFLDLSTLSPYVSGPNSVKVATPLKDLEAQNIKVNKAYLVSCTNSRASDIAAAARVFKEAAEKNGGKVPKIADGVEFYVAAASIPEQLAAEEAGDWQALLDAGATPLLPGCAQCIGLGTGLLEAGEVGISASNRNFKGRMGSTDAKAYLGSPEVVAASALTGKLSGPGWYQAPEGLTEVVRGEGDGIREEDRMLTAEQALEKLIGQIDNLVADGEKQFAPEESEESSGDSLTEVYPGFPERVSGEIVFCDADNINTDGIYPGKYTYQDDVSQETMAQVCMSNYDAQFSSIAKEGDILVTGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLINRLRESFSGEGSDKSLTRRTGWTLTWDVRRSRIEVQEGENGPKWTHQVGELPPNVQEIIAKGGLEKWVKNEIGA
What is the function of this protein?
Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
What are the official names of this protein?
Homoaconitase, mitochondrial, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ICOS_HUMAN
Sequence: MKSGLWYFFLFCLRIKVLTGEINGSANYEMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFKVTLTGGYLHIYESQLCCQLKFWLPIGCAAFVVVCILGCILICWLTKKKYSSSVHDPNGEYMFMRAVNTAKKSRLTDVTL
What is the function of this protein?
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.  Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens.  Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10.  Prevents the apoptosis of pre-activated T-cells.  Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
What are the official names of this protein?
Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: RL28_PORGI
Sequence: MSKICQITGKKAMVGNNVSHSKRRTKRVFDVNLFRKKFYWVEQDCWVVLRISAAGLRLINKIGLDAAIKRAAEKGFLNA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: GCNT3_RAT
Sequence: MVSWRRFCWHYHGWTLGCYMLLAIIALKLSLRLKCDFDVMDLDSKEFQSQYCRDLLYKTLELPAKSSINCSGVIRGEQKAVTQALLNNLELKRKRQSFTEADYLSMTADCEHFKTQRKFIQVPLSKEEANFPIAYSMVIHEKIENFERLLRAVYTPQNIYCVHVDQKSSETFQQAVRAIVSCFPNVFIANKLVSVVYASWSRVQADLNCMEDLLQSPVPWEYLLNTCGTDFPIKTNAEMVKALKLLNGQNSMESEVPPPHKTFRWKYHYEVADTLYRTSKEKTPPPNNITMFTGNAYMVASRDFIEHVLSNSKARQLIEWVKDTYSPDEHLWATLQRASWMPGSDPLHPKFDLSDMRSIARLTKWQDHEGDIENGAPYTSCSGIHQRAICVYGSGDLHWILQNHHLLANKFDPKVDDNVLQCLEEYLRHKAIYGTEL
What is the function of this protein?
Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides.  Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis.  Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
What are the official names of this protein?
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3, C2GnT-mucin type, C2GnT-M, dI/C2/C4GnT, dIGnT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: MLTF_PSEF5
Sequence: MFSPMALRPRCAKWLIVTGLFLMLGACVEKPSTLERVKEDGVLRVVTRNSPATYFQDRNGETGFEYELVKRFADDLGVELKIETADNLDDLFDQLGQPKGPVLAAAGLVSSEQRKQQVRFSHPYLEVTPQVIYRNGRSRPTTAQDLVGKHIMVLKGSTHAEQLAELKLKYPGIEYEESDAVEVVDLLRMVDEGQIDLTLVDSNELAMNQVYFPNVRVAFDLGDARSQSWAVAAGDDNSLLNEINSFLDKVEKNGTLQRLKDRYYGHVDVLGYVGAYTFAQHLQQRLPKYEKHFKASAKQEKLDWRLLAAVGYQESMWQAEVTSKTGVRGLMMLTQNTAQAMGVSNRLDPKQSISGGAKYLAYIKEQLDDKIEEPDRTWFALAAYNVGTGHLDDARKLAEKEGLNPNKWLDVKKMLPRLSQKQWYSKTRYGYARGGEPVHFVANIRRYYDILTWVTQPQLEGDQVAEGNLHVPGVNKTKPPEENPPL
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: TATB_ACISJ
Sequence: MIDIGLSKMALIGAVALIVIGPEKLPRVARTVGTLLGKAQRYVADVKAEVNRSMELDELRKMKDTVENAARDVEQTIHTSASDFQKDMEHSLGDASATGSTYGVDQGLSTVVPAYKHPAKNWRLKRGAMPQWYKARAGVRTRVQSGAARVARFRPQKFH
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: EFP_SALTI
Sequence: MATYYSNDFRSGLKIMLDGEPYAVESSEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.