PharMolix/UniProtQA huggingface dataset:
Protein: SRTX_ATREN
Sequence: MALLPRLAAGGLLLLLALAALEGKPAPSALSQLLEKRSEDQAAAGRIIDGGDTKQAARDPSPQRNVEPLCSCKDMSDKECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCTCNDMTDEECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCSCKDMTDKECLYFCHQDVIWRDTKQAARDPSPQRNVEPLCTCNDMTDEECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCTCNDMTDEECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCTCKDMTDKECLYFCHQGIIWRDTKQAARDPSPQRNVEPLCSCKDMSDKECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCTCNDMTDEECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCTCNDMTDEECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCSCKDMTDKECLYFCHQDVIWRDTKQAARDPSPQRNVEPLCSCKDMSDKECLNFCHQDVIWRDTKQAARDPSPQRNVEPLCSCKDMTDKECLNFCHQDVIWKNADTSANPEFLG
What is the function of this protein?
Vasoconstrictor activity.  Causes cardiac arrest probably as a result of coronary vasospasm (By similarity).  Displays high agonistic activities towards endothelin-2 receptor (EDNRB) (displays affinity in the picomolar range) and endothelin-1 receptor (EDNRA) (lower affinities) (PubMed:21889567).
What are the official names of this protein?
Sarafotoxin.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MGRB_SHIB3
Sequence: MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MRAZ_KORVE
Sequence: MFRGNHPTRIDDKGRLKVPADFKREIEDKFQNQTFYVTSFNGKEARLYPMEEWERFEAKLAALPSLNPTRQKLLNVSNYYGQVVEMDGQGRVTIPGLLREAAEIKGEVAVMGFLQYLVVRNAEHLKNEIESAPFTAEDEKTLSDLGI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS19_YERP3
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPIRTWSRRSTVFPNMIGLTIAVHNGRQHVPVFVSDEMVGHKLGEFAPTRTYRGHAADKKAKKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: HSCB_SHISS
Sequence: MDYFTFFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQLAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREELDEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNEAWDAAADTVRKLRFLDKLRSSAEQLEEKLLDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: RL10_GLAP5
Sequence: MALNLQDKQAIVAEVNEAAKGALSAVVADSRGVTVEKMTELRKAAREAGVSMRVVRNTLLRRAVEGTEFECLKDTFTGPTLIAFSNEHPGAAARLFKDFAKANKEFEVKGAAFEGKIQDVEFLATLPTYEEAIARLMGTMKEAAAGKLVRTLAALRDKLQEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RGSL_HUMAN
Sequence: MSSAEIIGSTNLIILLEDEVFADFFNTFLSLPVFGQTPFYTVENSQWSLWPEIPCNLIAKYKGLLTWLEKCRLPFFCKTNLCFHYILCQEFISFIKSPEGGEELVDFWILAENILSIDEMDLEVRDYYLSLLLMLRATHLQEGSRVVTLCNMNIKSLLNLSIWHPNQSTTRREILSHMQKVALFKLQSYWLPNFYTHTKMTMAKEEACHGLMQEYETRLYSVCYTHIGGLPLNMSIKKCHHFQKRYSSRKAKRKMWQLVDPDSWSLEMDLKPDAIGMPLQETCPQEKVVIQMPSLKMASSKETRISSLEKDMHYAKISSMENKAKSHLHMEAPFETKVSTHLRTVIPIVNHSSKMTIQKAIKQSFSLGYIHLALCADACAGNPFRDHLKKLNLKVEIQLLDLWQDLQHFLSVLLNNKKNGNAIFRHLLGDRICELYLNEQIGPCLPLKSQTIQGLKELLPSGDVIPWIPKAQKEICKMLSPWYDEFLDEEDYWFLLFTTQNRFISSRQHKREFIGKEENILLYKRIQQSLELSQALADMKEMDYRQWRKIATEDLKQGGSLQVELTSPVFLTDITKMSFEELCYKNPKMAIQKISDDYKIYCEKAPKIDFKMEIIKETKTVSRSNRKMSLLKRTLVRKPSMRPRNLTEVLLNTQHLEFFREFLKERKAKIPLQFLTAVQKISIETNEKICKSLIENVIKTFFQGQLSPEEMLQCDAPIIKEIASMRHVTTSTLLTLQGHVMKSIEEKWFKDYQDLFPPHHQEVEVQSEVQISSRKPSKIVSTYLQESQKKGWMRMISFIRSFCKYRRFMLNPSKRQEFEDYLHQEMQNSKENFTTAHNTSGRSAPPSTNVRSADQENGEITLVKRRIFGHRIITVNFAINDLYFFSEMEKFNDLVSSAHMLQVNRAYNENDVILMRSKMNIIQKLFLNSDIPPKLRVNVPEFQKDAILAAITEGYLDRSVFHGAIMSVFPVVMYFWKRFCFWKATRSYLQYRGKKFKDRKSPPKSTDKYPFSSGGDNAILRFTLLRGIEWLQPQREAISSVQNSSSSKLTQPRLVVSAMQLHPVQGQKLSYIKKEK
What are the official names of this protein?
Regulator of G-protein signaling protein-like.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ARP9_YEAST
Sequence: MAPFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNKAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLIIEPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWKKSGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF
What is the function of this protein?
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning.  RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA.  The reaction requires ATP and involves an activated RSC-nucleosome intermediate.  Remodeling reaction also involves DNA translocation, DNA twist and conformational change.  As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton.  This subunit is involved in transcriptional regulation.  Heterodimer of ARP9 and ARP7 functions with HMG box proteins to facilitate proper chromatin architecture.  Heterodimer formation is necessary for assembly into RSC complex.  Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, is required for the positive and negative regulation of gene expression of a large number of genes.  It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
What are the official names of this protein?
Actin-like protein ARP9, Chromatin structure-remodeling complex protein ARP9, SWI/SNF complex component ARP9.
What is the protein family that this protein belongs to?
Belongs to the actin family.
Protein: AROA_SYNSC
Sequence: MSGTGQSDDPRELKAGGSLQGRVKVPGDKSISHRSLLFGAIAEGTTTIDGLLPAEDPLSTAACLRAMGVSISPITDGGIVTVEGVGVDGLQEPAEVLDCGNSGTTMRLMLGLLAGRDGRHFVLDGDASLRRRPMRRVGQPLASMGAEVRGRDGGNLAPLAVQGRQLKGTVIGTPVASAQVKSALLLAALTAESPTTVIEPAQSRDHSERMLKAFGADLTVGGEIGRHISVRPGATLQGKNVVVPGDISSAAFWLVAGALIPGADLTIENVGLNPTRTGILEVLEQMGALIEVLNPRDVAGEPVGDLRVTHGPLKPFNFGEEIMPSLVDEVPILSVAACFCEGESRISGASELRVKETDRLAVMARQLKAMGADIDEHEDGMTIRGGRPLKGAALDSETDHRVAMSLGVAAMLADGNSSLARSEAAAVSYPSFWDELERLRC
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK_BACCZ
Sequence: MPKVRTKDLIEQFQLELISGEEGIHRPIDTSDLSRPGIEMAGFFTYYPADRVQLLGKTELTFFDTLTSDQKQERMKALCTEETPCIIVTRNQDVPDELLQASRESGMPLLRSSQTTTRLSSRLTNYLEGKLAPTTAVHGVLVDIYGVGVLITGQSGVGKSETALELVKRGHRLVADDSVEIRQEDEDMLVGSSPDLIEHLLEIRGLGIINVMTLFGAGAVRNYKRITLVINLEIWDQKKNYDRLGLDEEKMKIIDTELTKITLPVRPGRNLAVIIEVAAMNFRLKRMGVNAAQQFSERLMSAIELGNQE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue.  Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: GID4_HUMAN
Sequence: MCARGQVGRGTQLRTGRPCSQVPGSRWRPERLLRRQRAGGRPSRPHPARARPGLSLPATLLGSRAAAAVPLPLPPALAPGDPAMPVRTECPPPAGASAASAASLIPPPPINTQQPGVATSLLYSGSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTFFEGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYAKSFNSDDFDYEELKNGDYVFMRWKEQFLVPDHTIKDISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHVPEHSAPIYEFR
What is the function of this protein?
Substrate-recognition subunit of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (Probable) (PubMed:29911972).  Binds proteins and peptides with a Pro/N-degron consisting of an unmodified N-terminal Pro followed by a small residue, and has the highest affinity for the peptide Pro-Gly-Leu-Trp (PubMed:29632410).  Binds peptides with an N-terminal sequence of the type Pro-[Ala,Gly]-[Leu,Met,Gln,Ser,Tyr]-[Glu,Gly,His,Ser,Val,Trp,Tyr].  Does not bind peptides with an acetylated N-terminal Pro residue (PubMed:29632410).
What are the official names of this protein?
Glucose-induced degradation protein 4 homolog, Vacuolar import and degradation protein 24 homolog.
What is the protein family that this protein belongs to?
Belongs to the GID4/VID24 family.
Protein: G6PI_BRUC2
Sequence: MARDATKLEATVAKLKKHWAESAPRDMRAAFSADPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHDGPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAAVSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLVAHLHARRKA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OGG1_HUMAN
Sequence: MPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLRQSRHAQEPPAKRRKGSKGPEG
What is the function of this protein?
DNA repair enzyme that incises DNA at 8-oxoG residues.  Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA.  Has a beta-lyase activity that nicks DNA 3' to the lesion.
What are the official names of this protein?
N-glycosylase/DNA lyase.
What is the protein family that this protein belongs to?
Belongs to the type-1 OGG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus speckle. Nucleus matrix. Note=Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. SUBCELLULAR LOCATION: [Isoform 1A]: Nucleus. SUBCELLULAR LOCATION: [Isoform 2A]: Mitochondrion.
Protein: GLRX_RICCO
Sequence: MAMTKTKELVSSNAVVVFSKTYCPYCTSVKKLLDQLGAKYKVVELDTESDGSEIQTALAEWTGQRTVPNVFIGGKHIGGCDSTTAKHSQGQLVPLLTEAGAV
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins.
What are the official names of this protein?
Glutaredoxin.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CPYC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_PSEP1
Sequence: MTELELLGPRASGEPLGTAVLKAVAEDFQVDEVLDIPLSGQGEHLWLWVEKRDLNTEEAARRLARAAGVPVRSISYAGLKDRQALTRQWFSLHLPGKADPDLSRAEDASLRVLKQVRHQRKLQRGAHSANGFTLRLTALAADHQAVDARLEQLRQQGVPNYFGTQRFGHGGGNVHDALDWAARKALPEQRNVRSRLLSAGRSYLFNQLLAARVADGSWARAQVGDLLAFTDSRSFFPAGEAECADPRLAILDLHPTGPMWGEGASPAGAAPAQLENAIGARQPALCQWLAQAGMDHERRILRLPIGGLTWHYPEPDILQLEFVLPAGCFATVVVREVVDLVSAGQTDSPCVF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: F200A_HUMAN
Sequence: MTPESRDTTDLSPGGTQEMEGIVIVKVEEEDEEDHFQKERNKVESSPQVLSRSTTMNERALLSSYLVAYRVAKEKMAHTAAEKIILPACMDMVRTIFDDKSADKLRTIPLSDNTISRRICTIAKHLEAMLITRLQSGIDFAIQLDESTDIASCPTLLVYVRYVWQDDFVEDLLCCLNLNSHITGLDLFTELENCLLGQYKLNWKHCKGISSDGTANMTGKHSRLTEKLLEATHNNAVWNHCFIHREALVSKEISPSLMDVLKNAVKTVNFIKGSSLNSRLLEIFCSEIGVNHTHLLFHTEVRWLSQGKVLSRVYELRNEIYIFLVEKQSHLANIFEDDIWVTKLAYLSDIFGILNELSLKMQGKNNDIFQYLEHILGFQKTLLLWQARLKSNRPSYYMFPTLLQHIEENIINEDCLKEIKLEILLHLTSLSQTFNYYFPEEKFESLKENIWMKDPFAFQNPESIIELNLEPEEENELLQLSSSFTLKNYYKILSLSAFWIKIKDDFPLLSRKSILLLLPFTTTYLCELGFSILTRLKTKKRNRLNSAPDMRVALSSCVPDWKELMNRQAHPSH
What are the official names of this protein?
Protein FAM200A.
What is the protein family that this protein belongs to?
Belongs to the FAM200 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HSLO_CLOAB
Sequence: MADKLVKATAKNGDVRIIAAITTDMVNEGVKTHKCAPTAAAALGRMLTAGVLMGAQLKAESDSITLKINGGGIAKSVTVTSYSDAHVKGYIANPNADLPVNSQGKLDVGGIIGKNGNLLVIRDMGLKEPYVGQVPIYTGEIGDDIAYYYVNSEQTPSAVGLGVLVDKDLSIKASGGFIIQMMPGADDLVADLITYRLQEIPSITDLIAKGMSVEDILEFIFEDMDLKILDEGIVPEYRCDCSRDRVEKALISIGMKDLKEIYDDGKQEEVVCNFCNKKYVFTNDEVGSLIKRLENNK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_ECO45
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAISANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTPSQMYQSIKKLSALPDDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: LETM2_MOUSE
Sequence: MAFYSYNSFLAIFWTRLPGHSVYPSCSHFPSLAFLHLPDSHLRTAYIKNCGSRKYSYPSLTGNNKVHPLRTRLPQKLHTTCWLQHVPGKPQLEQTGKPKAASPQPTKEAKTETTEEKRSLRQKIVNELKYYYKGFSLLWIDTKVAARIVWRLLHGNALTRRERRRLLRTCADVFRLVPFMVFIIVPFMEFLIPVFLKLFPDMLPSTFESESKKEEKQKKTMAAKLEIAKFLQETMTEMARRNRAKLGDASSQLSSYVKQVQTGHKPSTKEIVRFSKLFKDQLALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMTLKSIKADDEIIAKEGVKALSVSELQSACRARGMRSLGLTEEQLCQQLTGWLDLHLKENVPPSLLLLSRTFYLIDVKPKPIELPPNIETPKPNLGIPTPPPPESKENLTDSAPQLKGTKDEEFIQLPPVPSSLIAPAATISKEAILQAKSQETSQNSKADSKGA
What are the official names of this protein?
LETM1 domain-containing protein LETM2, mitochondrial, LETM1 and EF-hand domain-containing protein 2, Leucine zipper-EF-hand-containing transmembrane protein 1-like.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: THIG_ECOLU
Sequence: MLRIADKTFDSHLFTGTGKFASSQLMVESIRASGSQLVTLAMKRVDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDARWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAIADDPVNMAKAFRLAVEAGLLARQSGPGSRSHFAHATSPLTGFLEASA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_LACPL
Sequence: MLMNLQFFSHHKGGGSTANGRDSAGRRLGAKRADGQTVKNGNILYRQRGTHIYPGVNVGRGGDDTLFAMADGVVRFERKGRDKRQVSVYPAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PRSS8_HUMAN
Sequence: MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH
What is the function of this protein?
Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates.  Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
What are the official names of this protein?
Prostasin, Channel-activating protease 1, CAP1, Serine protease 8.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
[Prostasin]: Cell membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Prostasin light chain]: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus. SUBCELLULAR LOCATION: [Prostasin heavy chain]: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus.
Protein: CRG1_RANTE
Sequence: WMLYEHPNYTGHQYFLRRGEYPDFQQWMGLNDSIRSCRVIPQHRGSFRLRIYEREEFRGQMMEFTEDCPQVHEEFNYHDIHSCNVLEGHWILYEQPNYRGRQYYLRPGEYRRYTEWGAVTPRVGAFRRVQEMF
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin 1, Gamma-crystallin I.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: MCP4_THEMA
Sequence: MRSIASKVLVIGVVVVLAFFVTQYVLLNTTVFNSIMERKKEEAKHLVESVYGILERAYEMEQKGELTREQAQELAKSLIGKIRYDDNNYFWINDTHPRMVFHPIKPEMNGQDLSNYKDPNGVYLFNEMVKVAKEKGEGFVSYSWPKAGSDKPEPKISYVKLFEPWGWIVGTGIYVDDVKVTVGNLIFRNVLTVSVIGIAVIIMIFFYGRVLSRKTKAVLSALEKISSGDLSVSVDIKSKDEFGLIAQKLNETVGNLRKMVQEIDKSQDEVERVSEELFALSQQLRSALEEIARASDTISKEVQNASASIEEVTSGSEEVSANSQNISKLIQEISENADNIADFARNGQRVLEEAVKKVEDVSENSRETADVVSNVTESARNIEEIVRTIQSIAEQTNLLALNAAIEAARAGEAGRGFAVVADEIRKLAEESQKATEEISQILENIREGVERTNEMSKKNVEITKDARRLVEESYESFNQIVTRIEDLAARIEGIAASAQELSAASEEMSSALDAVAKTTTTVADEVEEVSENITEQEKAAKRIADIGTELKKLSDELKEDVERFKI
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
What are the official names of this protein?
Methyl-accepting chemotaxis protein 4.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAB45_BOVIN
Sequence: MASRQAPLCGLAPCCLWLLGVVLLMNASARPANHSSARERAGNREENEILPPDHLNGVKLEMDGHLNKDFHQEVFLGKDMDDFEEDAEPRKSRRKLMVIFSKVDLNTDRRISAKEMQKWIMQKTAEHFQEAVAESRAHFRAVDPDGDGHVSWDEYKVKFLATKGHNEREVAEKIKNKWDLNIDEETQEVLENLKDRWYQADNPPPDLLLTESEFLSFLHPEHSRGMLQFMVKEIIRDLDQDGDKKLSLSEFISLPVGTVENQQGQDVDDSWVRDRKREFEELIDANHDGIVTMAELEDYMDPMNEFSALNEAKQMIAIADENQNHYLEPEEVLKYSEFFTGSKLVDYARSVHEEF
What is the function of this protein?
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
What are the official names of this protein?
45 kDa calcium-binding protein, Cab45, Stromal cell-derived factor 4, SDF-4.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Golgi apparatus lumen.
Protein: Y1054_HAEIN
Sequence: MKGKTAAVQIKNRAKAAATVSEKQLIGRGVRYFPFAFEDKQPNKRKFDNDMQHELRILEELFYYTHDEQSRYISELKAELRKDGFIPENDKDKVLTTFKLKSEFADNENFKNLLIWANKKIPNPNAKANNADSLKANPPPQPLPFPVHGKLLQETQFTADENDEKARQIGTQNNFTETIEMSEIERHIFNKALHIKGKNSQSLFHFDRLQSKLNIQNRNELQNNLLKDWQIEFLGLGQDKQISPDDKLAGCLKILEMVEKHLNESDIPFIGTKEFTPKKLWEIFGTPKQKWVKKDDVKTAIATQNDWYVMDNFAGTSLEEALIQFISERLGDLKSKYDVHLIRNEEVFKLNNFADGEGFMPDFILLLKDKQKSSSNGVNDFLHYQIFIEPKGEHLVETDMWKKEFLEAITAEYGKDKILQKDTPHYRLIGLPFFTDNEKNPKEYEQFTKSFPLGEASLEK
What are the official names of this protein?
Uncharacterized protein HI_1054.
Protein: CH10_MYCLB
Sequence: MAKVKIKPLEDKILVQAGEAETMTPSGLVIPENAKEKPQEGTVVAVGPGRWDEDGAKRIPVDVSEGDIVIYSKYGGTEIKYNGEEYLILSARDVLAVVSK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.