PharMolix/UniProtQA huggingface dataset:
Protein: SEH1_PONAB
Sequence: MFVARSIAADHKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSESGDWHCTASWKTHSGSVWRVTWAHPEFGQVLASCSFDRTAAVWEEIVGESNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHMGLMLATCSADGIVRIYEAPDVMNLSQWSLQHEISCKLSCSCISWNPSSSRAHSPMIAVGSDDSSPNAMAKVQIFEYNENTRKYAKAETLMTVTDPVHDIAFAPNLGRSFHILAIATKDVRIFTLKPVRKELTSSGGPTKFEIHIVAHFDNHNSQVWRVSWNITGTVLASSGDDGCVRLWKANYMDNWKCTGILKGNGSPVNGSSQQGTSNPSLGSNIPSLQNSLNGSSAGRKHS
What is the function of this protein?
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway.  Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex.  It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
What are the official names of this protein?
Nucleoporin SEH1, GATOR complex protein SEH1, Nup107-160 subcomplex subunit SEH1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex. Lysosome membrane.
Protein: RS7_THEP1
Sequence: MRRRRAEIRQVPPDPVYGDVLVAKLINKVMWDGKKTTAQKIVYGAFDIIREKTKKDPLEVFRQAVENVKPVLEVRPRRVGGATYQVPIEVQEPRRTSLALRWIVEAARARKGRPMKEKLAEEIIAAYNNTGTAIKKKEDTHRMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: YSHB_ECOLI
Sequence: MLESIINLVSSGAVDSHTPQTAVAAVLCAAMIGLFS
What are the official names of this protein?
Uncharacterized protein YshB.
Protein: MIC27_ASHGO
Sequence: MSRNFYNYDPTVDILQPPLIPDVILKSNLKELTLPTGNQVLESLPLTAWFHRTRSNIISHLTRYEAEWETQKSAARNELHSVKSYLKGNIFNDARELYALPETNILTICAYFAGRIITNRKNWGVSAATLQSVKSSVHRPSLMARVCTSIPSKMVLPWAMAGAVFKELAPTAFDNTITSLESDILDPGFVAQYKTLWRDYYTNGAKKASIEAAELLEGKLQGYIGFARNFIIYSTR
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit MIC27.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSRQ_PECCP
Sequence: MRLTLQHITRLKVLLHLAGFLPLLWLILSVDQGWFSADPAKDIQHFTGRMALKLLLATLLVTPLARYGKQPLLIRCRRLLGLWCFFWATLHLVSYALLELGLDHLALLGKELISRPYLTLGVISWLILLALAVTSPQIMMRKLGSQWQKLHNFVYLVAILAPIHYLWSVKTLSPQPILYALAALILLLFRYKKFRQWWR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y604_STRP4
Sequence: MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIGKESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPTLHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHAHVTALASRPKLIGGARAHYPQDAIRKS
What are the official names of this protein?
UPF0340 protein SPG_0604.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: HIS1_THESQ
Sequence: MLKLAIPKGRLEEKVMTYLKKTGVIFERESSILREGKDIVCFMVRPFDVPTYLVHGVADIGFCGTDVLLEKETSLIQPFFIPTNISRMVLAGPKGRGIPEGEKRIATKFPNVTQRYCESKGWHCRIIPLKGSVELAPIAGLSDLIVDITETGRTLKENNLEILDEIFVIRTHVVVNPVSYRTKREEVVSFLEKLQEVIEHDSNEQSRG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_DEIDV
Sequence: MANVESFDLDHTKVRAPYVRLAGVKTTPRGDSISKYDLRLLQPNQGAIDPAAIHTLEHLLAGYLRDHLQDVVDVSPMGCRTGMYMAVIGTPDEEGVLKAFEAALQDTAAHDRPIPGVSELECGNFRDHDLHAARQHAREALAQGLKVQQTVLLQR
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: UVRC_CHESB
Sequence: MNAADLGNTIISAEDSTLEWDRAGTETAATGVEVIQAVVKRLPNAPGVYRMVNTEGDVLYVGKARSLKKRVTNYAQGRGHSNRIERMIRETATMEFVVTRTETEALLLEANLIKRLRPRFNVLMRDDKSFPYILLTGNHPAPGIFKHRGARSRRGDYFGPFASAGAVGRTINSLQRAFLLRTCTDSVFESRTRPCLLYQIKRCSGPCTREISVEDYATLVKEAKDFLSGRSSTVKAEIATAMQEASQALDFERAAIYRDRLAALSHVQSHQGINPQGLEEADVFAIHQEGGQTCIQVFFFRTGQNWGNRAYFPKADPALGHGEVLGSFLAQFYDDKPCPRLILLSHPVEDQDLLAEALSARAGRKVQVSVPARGEKKDLTDHALQNAREALGRRLAETSSQARLLEGLAETFGLEAAPRRIEVYDNSHIMGTNAVGAMIVAGPEGFVKNQYRKFNIRSAEITPGDDFGMMREVMQRRFARLIKEQGLPGNGSEAEDSDASFPAWPDLILIDGGQGQMSAVRQILDDLGIADLVTAIGVAKGVDRDAGRERFFMEGRPPFTLPPRDPVLYFVQRLRDEAHRFAIGSHRARRKKEMVKNPLDEIAGIGPGRKRALLHHFGTAKAVSRAAVEDLMEVGGISESIARLIYNHFHESG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_COLP3
Sequence: MASTLKFIVIVPAAGVGKRMQANCPKQYLRINNETILSHTVMRLLSHPLISQVIVALGTEDQYFAESELAHHKDIIRVNGGTERVNSVLNGLKAVDSDKYPWVLVHDAARPCVSHQDIDKLITRCLRKDYGGILATPVRDTMKRGVLIKDSAKGDNTIIESTVEREQLWHALTPQMYKTDELTLAIEQALENSLKITDEASAIEQANLPSLLVSASSENIKITHPNDLALAEFYLNKQANNTN
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: WDCP_MOUSE
Sequence: MELGNGKLPRTGLNSLNQAVHPTWGLAWTDGNRVVLTDLQLHSGEAKFGDSRVIGRFESVCGVCWAPVRTVRSPALLAIQHRKLVSVWQLCPSTAGASKWQASQTSEVRESLPILPRGCVWHPKDAVLTVLTAQGVSIFPNVHQDGSRVKVDVNTKGRVYCACWTLDGQRLVVAIDSNLHSYIWDSSQKSLHSCSFCPVFPVNCSIRSIEATGNSQVAIATELPLHKLCSLNASEALDGPPNGDDGSVHTRPVDEQVATMDMNSGVTVSPFSVPLDLTHIHFNPSQAEQSSLICLRKKDYLTGTGQDSSHLILVTFKKAITITKKVAIPGILVPDLIAFNLTAELVAVASNTCNVILIYSAAPSSMPNIQQIQLESNERPKGICFLTDRLLLIAVGKQKPSEAAFLPSSEYGQYTVRLIVREMAQGSESSGTSAESQGAYSDFTALLSKADREKFTDSLSPGSSPLSQGLLLTPNSSTQSGRSGRALIQEIKSPLSPLSSDSVVHETLHRPPWLCPALPRPSRTPEHTSTPELNSPQRENLQKEKETCPLSRELEILSRHLVAMQQYLSELTGFLHKEKRVAPAYPPSQDAPYVHLIYQNPCSVGPTERRAVLLCDGKLRLSTVQQMFGLHLVEMLHEVLSSIPSNHMVTHNLHGPGGLFWSV
What are the official names of this protein?
WD repeat and coiled-coil-containing protein.
Protein: NU1M_SQUAC
Sequence: MLQHILLYLINPLAYIVPILLATAFLTLVERKILGYMQFRKGPNIVGPYGLLQPIADGVKLFIKEPVRPSTSSPFLFLATPTLALTLALLMWMPLPLPHAIINLNLGLLFILAVSSLTVYTILGSGWASNSKYALMGALRAVAQTISYEVSLGLILLSMIIFTGGFTLHTFNLTQETVWLLVPGWPLAMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAGGSFALFFLAEYTNILMMNTLSVILFMGSSYDPTMPQISTFYLMMKATLLTLIFLWIRASYPRFRYDQLMHLVWKNFLPLTLALILWHAALPIATASLPPLT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: STB1A_DANRE
Sequence: MSREKDDENLLRMTKDDLQRWIQAEVERNPHLMQRREQLAQVEEWVKQKERDSTCTRLLYSNACESVLECESVMKGLYALLGLDYRDEDSEEEGGGGQPHDVIQIADDEAERRGNVICNGEDDDNDDLVVIDLGATKETLEPMLEKVTVAIQKSSKLVQDLVQMVSKTSMGATSPLSTSSSDINRPSSSSTPEIVRPESVTPKLEITNSITIVKTESLSSVPKISSLFNSSEQCKSIADHDSYFKPTIKTEPEWTPLTPWEDSESSPFEKLIKTESQSTDVTPSVMTPNKQPELLSFQSTTKIKPEPQSTQANTELSSPPSNSKLLENHNSLSIAAIKNESQLKASVSEVDLLESDSEQSDNAATKTRFKPSEVTASSKLKSSGDHNSASASLNRTDPKVRPVTPSGTPPPSKSPPAVDNTASVETNQTDSELPTETPVEESTLPSNPKEAVIMSDAESTDKTEKPQTRKKSSKPSVTTTSPESRLTSSKSPPVTKTSSTQKETARAQSPSDSIDESADMEDSPDEPSNSPTESPTKTPDKTTRNDAPAKPSKAKKSSKHSSSESSKTLKEIKLKVGAAVLGKKRHNHWSRGTVQEVETEDDGNTYKVEFKKGKTIVLSANHVAAYKPPSLKDLYIGCRVVASAKSENGKSLYNAGVMVELPERKNRMRFLVFFDDGLATYLALPDLYFVCKQTKKVWREIKDESSRKQVKDYLQVYPNPIAVVLRLGQETKAVRNGQFEDCTVLQLDGSLVQICYKNDKQKEWIYKGSDKLEHILTIKNRHKQHSHKKHHSPEGKTQSSQPKTLHSSKSASTSTSSANVSPVSSDSVSPARVTRQSDKTKTSISPQKIMSPAFQPKVVLQKISLPSSISPAARVSNSNTNSSLISAKRPAPDEEEDEYFSEDEVEVLEQEQNKSVYLHQRCCPACLEEVRPHQVDIHHGKNPLLIPLLFKFRRMTARRRIDGKLFFHIFYRSPCGRSLCDMQEVQDYLFETRCDFLFLEMFCMDPFVLVNRARPPSTTTGQPHLYLPDISEGKEVMPVPCVNEVDNTLAPNVTYTKDRVPARGVFINTSSDFMVGCDCTDGCRDRSKCACHKLTIEATSLCTGGPVDVSAGYTHKRLPTSLPTGVYECNPLCRCDPRMCSNRLVQHGMQLRLELFMTQHKGWGIRCKDDVPKGTFVCVFTGKIVNEDKMNEDDTMSGNEYLANLDFIEGVEKLKEGYESEAYCSDTEVESSKKTITMKTGPLLKNSLYKEDSSSGEEPMEVDTAKDKVKVHDKPLGERKLPNKPHETPKDTQKKISELRKNDGQESSGPKRCFAIKSFQRRVKPLESTEAQKEKTKTPKNTRGLFNDEDACYIIDARQEGNLGRYINHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIKAGTELTWDYNYEVGSVEGKVLLCCCGSLRCTGRLL
What is the function of this protein?
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3.  H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones.  Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.  H3 'Lys-9' trimethylation is coordinated with DNA methylation.  Plays a role in promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) or other tumor-related genes.  Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs).  Associates at promoter regions of tumor suppressor genes (TSGs) leading to their gene silencing (By similarity).
What are the official names of this protein?
Histone-lysine N-methyltransferase SETDB1-A, SET domain bifurcated 1A.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with non-pericentromeric regions of chromatin. Excluded from nucleoli and islands of condensed chromatin (By similarity).
Protein: PR8A4_RAT
Sequence: MMKLALSQPPFSGTLLMLVVSILLLWEKAASIPACMVEEGDCWDPLQETFNSAIQRAETLCNLADQLYVEFYQNQFSSRQFADLNSKLIKRDETVLKAGIYCHSTLAKPQTRGGNFEIEEHLKMLINFVGSWISPLFHLVIELSAMEGVPETILCKVKDLEENNRQLLDDLRWILTKVSPTAEIREEFPSWEHLSFLKSSNKNNKFLAMFNLSNCLDNDTKFTLHHLRIFKCLITGKDC
What are the official names of this protein?
Prolactin-8A4, Growth hormone-related placental protein 3, Placental prolactin-like protein H, PLP-H, PRL-like protein H.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SIF2_DROME
Sequence: MEQKCIRRKGSVRLTEPTGHAHVRIEQRPQLPPRRQKSAEEVATMPKSALRQPPEQLEWFDRRAQQRHSARSAEGGQVREETMEWLKLQKTASPIQPVRTSSGPSEITVLKDELPDWLLDHLPRKKERERDRLPSDADKAVGSAYAKALADLLKKPLSRQGSGPCEFSLLKTDIVEWLTKMQSSSGTDRGKSRRSHHRRNGSGGDAQPRSNSQEDAQDQSKTSHRKRHSLGHSGAVSEEEQQQLTADWIAYPLHKLQSLGKQPPPAQPPERMSIPSGYAVPSALSHTPLCQRREERSRERRLRHSASEVVGSGGAGAASTSNTAHLERLYAKPHKERYQYVPKTKESSGRKERSRRHQTQRSATVSDMSAQRSGGHKRKSSSAERAPRSPSPGPCTDPDCPLLPICTDPHCRYQECQARQCITSSVSSVNLARHQQLAQVQLHAVPAHLVGAMGSDVPTTPSTTATPPPPTGGGTMGVGATGAGAGATSERRLVICHDCRSCAPLLSCRNRKCLNAAKCNSLPRCAADFNRLRTQLSQPPTTLDDIEPAPLDDLEMQPLPSPPHPHPHHHYRSNSQPNTLQRGDSASSAGMGAGVGGAGHGGLGGPGSGLAWLEPTTTLVQPLPAYVHHSNGKLMKSASAASLNSRRRRHKTVHFGENLLREVCQNRKLIKTEAQVPSGSAPMKANIQMLYNFVEGVLSAWVDDDEDQVRSGAESEPEHGVVPMQPIHRCNRLRYQCIRRVVEEAADLQGTLKLGNSRYRHRHWRSTAKQCNEMFLRKISDDDRMSLTTAVSDEDDGESVMASPYKAKATGTAASSFNCTGAVRKAGFLSVKKWLLRKKHQIELARKRGWKGYWVCLKGTTLLFYPCDSREGRSVEAAPKHLIIVDGAIMQPIPEHPKRDYIFCLSTAFGDAYLFQAPCQVELENWVNSIHSACAAAFARHRGKTGTLHLLQEEIFRLEKAIESDHKLKHMAELQQSVVTDQETRHQIQTQILQWEENLERLHCEQFRLRCYMASLQSGELPNPKSLLTHVSRPTKNTLNKLGVFTVSSFHAFICARSPSLLNNLLAGRGATKRRPPMLSRSNSGSSRRSMQMNSRDEPEKTFKVAMPDNAYSTVYLRDAMSVEEFLASACARRNLNPMEHFVRVKKRRDMEDHNYFVPHRNDLIENYLHNHEFVEVCMKILYQVELQRTTLEQMWGFSVEAELIENAERQDELCCYVSRVEDKSVAMHNGIIKGDEIMVINGAIVSDLDMMYLESVLQEEQSLSMMMRSSRTEPPDLVGIMRVTDDMIDSLVCPPPPTDPPVMSEEMITGLIVPAPGWNGTSKDLYSPEAESSPATSFVDPAAMAAQLAVGGVGGVVVGGLGVAKPTSRTSSFEIENLLKTAEQVTGFCRSPQETRKSSPTGSVTSSVSTTALTPSRQLTDAEKLRKVVMELVDTERTYVKHLNNLLEHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFLQNLEESLDLEPDFNKFEHCGQFRNVLFAIGSAFLYYVNHFKLYSSFCASHSKAQKVLHPNEGNHALQEFLAARNPKQQHSSTLESYLIKPIQRILKYPLLLQQMRNLTDTRADEHVHLCEALKGMEKVAEHINEMQRIHEEYGAIFDHLFRQHQKSCKQPIDLSPGDLLYYGGVEWLNISDFLGKIKKGLELHAMCFVFKSAVVFLCKERLRQKKKLMGVSSKNATNEVEIIRYQVLIPVTEVQVRASSAKDMDSHFLWELIHLRSQLQRRSEKVYVLSNSTADFRNAFLKTIRQIIRESVRNMSIPMKNFGGSSGSVSGHSSQGMGSMGYPGNSQTLERPKQQITIVHGSHTLGKPKKKSGSQRHSAGNIDYDNLSGSQEADDLPPSVGVVHYASGHTHGQQMQPAGFRGRSKTVGDVTEITCSSPEPHQQQQQQQQQQQQLMQQGHAHAHPHPHPHPREPPPPPIRQPHLHHHSSDIERIDPGTKSEGEEDSQQGTIRPKATLGRTPNHLTLSTTSTLSVGSTGSQARLIQSSHPPASYQPVLMKDLGSPVWKPRDMINLGTDPQSTTRKDDVKN
What is the function of this protein?
Regulates synaptic differentiation through the organization of actin cytoskeleton possibly by activating Rho-like GTPases.  Is likely a factor in the cascade of Rac1 or Cdc42 in the neurons (PubMed:8999801).  May play a role in maintaining proper septate junction functions.  Required for eye development and most likely affects corneal lens-formation (PubMed:30290152).
What are the official names of this protein?
Protein still life, isoforms C/SIF type 2.
What are the subcellular locations of this protein?
Synapse. Note=Localizes to the submembranous region of synaptic terminals.
Protein: COBQ_STRAW
Sequence: MSGGLLIAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTREGAEIGRAQAMQAQAARVEPTALMNPVLLKPGSDRSSQVVLMGRPVGEMSARGYHGGRQEALLGTVLDCLAELRGTYDAVICEGAGSPAEINLRRTDIVNMGIARNARLPVLVVGDIDRGGVFASFFGTVALLSREDQELVAGFLVNKFRGDVSLLEPGLDMLRNLTGRPSYGVLPFQHGLGIDEEDGLRVSLRGSVRESAVSSPVGEDILRVAVCAIPLMSNFTDVDALAAEPGVVVRFVDRPEELADADLVVIPGTRGTVKALEWLRERGLAEALRRRAAAGRPVLGICGGFQVLGEHIEDDVESRRGHVEGLGLLPVRVRFAREKTLTRPVGEALGEHVEGYEIHHGVADVTGGDPFLDGCRVGAVWGTHWHGSLESDGFRRAFLREVAAAAGRRFVPAAGTSFAGLREEQLDRLGDLIEEHADTDALWRLIESGAPSGLPFIPPGAPA
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: KHDC4_CHICK
Sequence: MSAGGGGQRDAGTAGGRRSKWDQPGPAPAFLLSGAAPLPGRPFPGGGDGGTAVGVSESSAAPSGALDAAAAVAAKINAMLMAKGKLKPAPNTADKLQALGKGPATNKSKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRLSGAAVSTRGRFMTAEEKAKVGPGDRPLYLHVQGQTRELVDRAVNRIKEIITNGVVKAATGSSPTFNGATVTVYHQPAPITQMSPAVGQKPPFQSGMHYVQDKLFVGLEHAVPTFNVKEKVEGPGCSYLQHIQIETGAKVFLRGKGSGCIEPASGREAFEPMYIYISHPKPEGLAAAKKLCENLLQTVHAEYSRFVNQITTAVPLAGFAQPAAINSVPSQPSYYPSNGYQSGYPVVPPPQQPVQPPYGVPGIVPPAVPMAPGVLTTLPTGVPPVPTQYPISQVQPPASTGQSPLSAPFLPAAAPVKTTLPAGTQPQVQPHPQGQKRRFTEELPDERESGLLGYQHGPIHMTNLGTGFSSQSEIDGAGSKPASSSGKERERDRQLMPPPAFPVTGMKSESEERNGVGSLPGSHDHQAKKMKTSEKGFGLVAYAGDSSDEEEEHGGHKNASTFSQGWSLGYQYPSSQQRAKQQMPFWMAP
What is the function of this protein?
RNA-binding protein involved in pre-mRNA splicing.  Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome.  Involved in regulating splice site selection.  Binds preferentially RNA with A/C rich sequences and poly-C stretches.
What are the official names of this protein?
KH homology domain-containing protein 4, Brings lots of money 7, Pre-mRNA splicing factor protein KHDC4.
What is the protein family that this protein belongs to?
Belongs to the KHDC4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LLDD_PSEA7
Sequence: MIISASTDYRAAAQRKLPPFLFHYIDGGAYAEYTLRRNVEDLSAIALRQRVLKNMSELSLETRLFDETLAMPVALAPVGLTGMYARRGEVQAARAAAAKGVPFTLSTVSVCPIEEVAPAIDRPMWFQLYVLKDRGFMRNALERAKAAGVTTLVFTVDMPVPGARYRDAHSGMSGPYAAPRRILQAMTHPAWAWDVGLLGKPHDLGNISTYRGNPTGLEDYIGWLGANFDPSISWKDLEWIREFWNGPMVIKGILDPEDAKDAVKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELAILADSGIRTGLDVVRMIALGADSVLLGRAFVYALAAAGEAGVRNLLELIEKEMRVAMVLTGAKSIGEISADSLVRELGA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FDHE_CROS8
Sequence: MSIRIIPQDQLEKSDKRTAEVIPPLLFPRLKNLYNRRAARLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKAAAEQGKPPLDIHVLPRDGHWQKLLQSLIAELKPEMSGPALAVIENLEKASAQELETMASALFSADFSAVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQFCPVCGSIPVSSMVHIGSSQGLRYLHCNLCETEWHVVRVKCSNCEQTRDLHYWSLESEQAAIKAESCGDCGTYLKILYQEKDPNVEPVADDLASLVLDARMEQEGFARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOC_BARBK
Sequence: MATETLVELAAYLKEKLGDKLEESALAFGELTIVSRLDAIIDVLMFIRDDSRCQFINIIDISGVDYPARDKRFDVSYQLLSPFQNLRLRVKVRTDEDVPVPSVCSVYPGAEWYERETYDMYGILFSGHPDLRRILTDYGFEGHPLRKDFPVTGFVECRYDNEAKRVIYEPVVLRQEMRNFDFLSPWEGADYVLPCDKKAKGNGDK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BGAL_PHODC
Sequence: EIQNAGLYAILR
What are the official names of this protein?
Beta-galactosidase, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: COAA_SHEPC
Sequence: MTSKNPIQKALYLTFERAQWSELRDSVPLTLSERDLENLRGINEKVSLSEVTDIYLPLSRLLNLIVKSKQQRGLVLDEFLGQKPFHSPYIISIAGSVAVGKSTTARVLQALLQHWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFISAVKSGQPHTKAPIYSHVTYDRVRNQHQIVSQPDILILEGLNVLQTGLDSPVDTRRPFVSDFVDFSIYVDAEESLLKQWYQERFLQFRKGAFSDAKSYFHHYANLTDDEANAIAANIWDTINGPNLQLNIQPTRERAHLILQKGQDHLMSHVLMRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_ALECH
Sequence: MAPNIRKSHPLLKMVNNSLIDLPTPSNISAWWNFGSLLAVCLVTQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIFLHIGRGLYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIAGITIIHLTFLHESGSNNPLGISSNSDKIPFHPYYSIKDILGLTLMFIPFLTLALFSPNFLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILLLIPFLHKSKQRTMTFRPLSQTLFWLLVANLLILTWIGSQPVEHPFIIIGQMASLSYFSILLILFPMIGTLENKILNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PAT_MYCTU
Sequence: MDGIAELTGARVEDLAGMDVFQGCPAEGLVSLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEVSHVGDDGVAIIARALPGMIVGEIALLRDSPRSATVTTIEPLTGWTGGRGAFATMVHIPGVGERLLRTARQRLAAFVSPIPVRLADGTQLMLRPVLPGDRERTVHGHIQFSGETLYRRFMSARVPSPALMHYLSEVDYVDHFVWVVTDGSDPVADARFVRDETDPTVAEIAFTVADAYQGRGIGSFLIGALSVAARVDGVERFAARMLSDNVPMRTIMDRYGAVWQREDVGVITTMIDVPGPGELSLGREMVDQINRVARQVIEAVG
What is the function of this protein?
Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS).  This acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes.
What are the official names of this protein?
Acetyltransferase Pat, GCN5-like enzyme, GCN5-related N-acetyltransferase, GNAT, Protein acetyltransferase, Pat.