PharMolix/UniProtQA huggingface dataset:
Protein: CY124_POSPM
Sequence: MHSLLVLFVSLLALGALKKHLDFRAAVDKIHNYPGLRFIFGVQSFIFGKRIPYFAAGGLSLWDTKHQDFVDHDADIISSVNIFPTCATYMIADAQAIKEITTNRARFPKPLQQYKILTFFGSNIVVTEADEWKRHRKISAPSFSERNNRLVWDETINIVKELSDDVWRGKNEVTMDNIVDLTVPIALFVIGVAGFGRRMSWVEDFTVPAGHSMPFKDALHLVSNHLWMKVLLPAWFLRSAPIPRVRKFHTAYEDLEKYMIEMIQARKTAEKKEERYDLFSSLLDANEEETDGNTKLSDSELMGNIFIYLIAGHETTAHTLAFTFILLALYQDEQEKLYQHIKSVVPDDRLPAYEEMGKLTYCYAMLLETLRMFPPVNLIPKQAAEDTTLHTSNMAGEPVAVPCLAGTALAIHTPGLHYNPRYWEDPFAFKPARFLGDWPRDAFLPFSAGPRSCLGRRFSETEAVAVLTYIVARWRIDVKEEPQFAGETFEQRKARLLDSKSAITLYPVRAPLVFKRR
What is the function of this protein?
Cytochrome P450 monooxygenase that is able to use trans-stilbene as a substrate for oxidation.
What are the official names of this protein?
Cytochrome P450 monooxygenase 124.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL31_CLOB8
Sequence: MREGIHPEYHHNTVVKCACGNTFTTGSVKEELKVEICSKCHPFFTGKQKIVDVGGRVDKFNKRFNIGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: SYQ_ECO81
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDB2S_TITCO
Sequence: MVSKSLIVLLLVSVLVSTFFTTGAYPTSYDDDFDALDDLDDLDLDDLLDLEPADLVLLDMWANMLDSQDFEDFE
What is the function of this protein?
May be an antimicrobial peptide.
What are the official names of this protein?
Anionic peptide clone 7.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_TERTT
Sequence: MAKLTKRQKAINEKVDFNKAYGIDEAVALLKELSTVKFPETVDAAINLGIDPRKSDQAVRGATSLPHGTGKDVRVAVFTQGAAADAAKEAGAEFVGMEDLADQIKGGMMDFDVVIADPAAMRVVGALGQILGPRGLMPNPKTGTVTPDVAGAVKNAKAGQVRFRADKGGVIHGGIGKVSFELNAIKENLEALVSDLKKAKPAAAKGVYLKKISLSTTMGPGLTIDQSSLEI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YCIB_PARXL
Sequence: MKFLFDLFPIILFFVAFKIWGIFTATAVAIVATLVQIAWVAFRHRKVDPMLWVSLGVVTVFGGATLVLHNDTFIKWKPTVLYWAFSVALIVSQLAFNKNLIEAMMGKQITLPHAIWGKLNVVWGVFFVLLGLVNLFVAYNYTTDQWVNFKLFGATGCLVVFIVGQSLWLSKYMKEE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTLD_ENTFA
Sequence: MNAVHFGAGNIGRGFIGEILAKNGFHITFVDVNETIIQALKERKSYTIELADASHQQINVENVTGLNNMTEPEKVVEAIAEADLVTTAIGPNILPRIAELIAQGIDARAEANCQKPLDIIACENMIGGSTFLAEEVAKYLKNPAYAEQWIGFPDAAVDRIVPLQKHEDPLFVQVEPFCEWVIDDTNRKAKEIQLEGVHYVADLEPYIERKLFSVNTGHATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGKLLVAKWNFDEQEHAAYIEKIIQRFQNKYISDAITRVARTPIRKLGAQERFIRPIRELQERNLVSPHLLAMIGIVFNYHDPEDEQSRQLQEMLDQESVDTVIAEVTGIEDPETVKNIKQNVERYARPQVA
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: SEC1_MOUSE
Sequence: MPSDSCLLSLTVLQRLRAICPPLSTFYLFFVIFVVSTIFHCHRRLGLVPAPWASPSLVVFPPRHMPREGMFTIRVKGRLGNQMGEYATLFALARMNGRLAFIPASMHSTLAPIFRISLPVLHSDTAKRIPWQNYHLNDWMEERYRHIPGHYVRFTGYPCSWTFYHHLRPEILKEFTLHDHVREEAQAFLRGLQVNGSQPSTFVGVHVRRGDYVRVMPKVWKGVVADRGYLEKALDRFRARYSSPVFVVTSDDMAWCRKSITASRGDVAFAGNGLQGSPAKDIALLMQCNHTVITLGTFGIWAAYLTGGDTVYLANFTQPNSPFHTVFKPEAAYLPEWVGIAADLGQPNTVGSGHASARAPKRHWGALL
What is the function of this protein?
Catalyzes the transfer of alpha 1,2-linked fucose to ganglioside GM1 and galacto-N-biose (By similarity).
What are the official names of this protein?
Galactoside 2-alpha-L-fucosyltransferase Sec1, Alpha(1,2)FT 3, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 3, Secretory blood group protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: PURA_BACHK
Sequence: MSSVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEELKYLHDRGVSTDNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLEQNLAQKNRLFEKMYDTEGFSVDEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSNPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGLTDLSLNSIDVLTGIPTLKICVAYKCDGKVIDEVPANLNILAKCEPVYEELPGWTEDITGVRSLDELPENARKYVERVSELTGIQLSMFSVGPDRNQTNIVRNVYEA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_CLOPD
Sequence: MERALILAASAIGAGLAMIAGIGPGIGQGFAAGKGAEAVGKQPEAQGDILRTMLLGAAVAESTGIYALVVALILLFANPLLNLL
What is the function of this protein?
In this organism this enzyme may function as an ATP-driven Na(+) ion pump to generate a Na(+) ion electrochemical gradient rather than as an ATP synthase.
What are the official names of this protein?
ATP synthase subunit c, sodium ion specific, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MOC2A_ORYSI
Sequence: MALDPKANHAAAAAASADNPTAAAAKAKVKVKVLFFARARDLTGVTEAPVEVPAGSTAGDCLARVLAAFPRLEEIRRSMVLALNEEYAPEDAAVGDGDELAIIPPISGG
What is the function of this protein?
Acts as a sulfur carrier required for molybdopterin biosynthesis.  Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group.  In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, Molybdenum cofactor synthesis protein 2 small subunit, Molybdenum cofactor synthesis protein 2A, MOCS2A, Sulfur carrier protein MOCS2A.
What is the protein family that this protein belongs to?
Belongs to the MoaD family. MOCS2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_CLAM3
Sequence: MTRHFLRDDDLSPAEQAEVLDLAVQLKRERWSERPLAGPQTVAVIFDKSSTRTRVSFAVGIADLGGVPLIISTANSQLGGKETASDTARVLERQVAAIVWRTYGQAGLEEMAAGTTVPVVNALSDDFHPCQLLADLLTIREHRGDPAGQTLTFLGDGACNMAQSYLLAGATAGMHVRIAAPAGYVPSEAVVADAERIAASTGGSVRVLTDPVEAVSGADVVVTDTWVSMGREEEKAQRLAELGAYQVTTELMEHAVDDAIFLHCLPADREYEVASEVIDGPRSVVWDEAENRLHAQKALLVWLLRQS
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPPA_PONAB
Sequence: MAAVVLAATRLLRGSGSWGCSRLRFGPPAYRRFSSGGAYPNIPLSSPLPGVPKPVFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVGLLADVVLQPRLTDEEVEMTRMTVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENIAKINREVLHSYLRNYYTPDRMVLAGVGVEHEHLVDCARKYLLGIQPAWGSAEAVDIDRSVAQYTGGIAKRERDMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMSGTVDAVELERAKTQLTSMLMMNLESRPVIFEDVGRQVLATRSRKLPHELCTLIRNVKPEDVKRVASKMLRGKPAVAALGDLTDLPTYEHIQTALSSKDGRLPRTYRLFR
What is the function of this protein?
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
What are the official names of this protein?
Mitochondrial-processing peptidase subunit alpha, Alpha-MPP, Inactive zinc metalloprotease alpha.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion inner membrane.
Protein: COQ7_NITMU
Sequence: MPNLDKLIIGFDHALRTLLTPAQTLRPVPGTQLPEAELNDLEKSESAALMRVNHVGEICAQALYQGQALTARNAEVQQTLAQAAREETEHLAWTERRINELSGRKSLLNPLWYGGSFAIGAFAGLLGDKWNLGFLAETERQVSAHLGGHLSRLPHADEKSRAIVTQMQIDEAGHATTAVAYGGAELPMPVKLVMRMASSVMTRTAYWV
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CLPS_PECCP
Sequence: MGNNSTWSQSENLTADKQKEKLQPPSMYNVVLNNDDYTPMEFVIDVLQKFFSYDIERATQLMLTVHYQGKAICGVFSAEVAETKVVQVNRYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: SYL_SALHS
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3407_BRUSU
Sequence: MRSSIHASRLRKMGQSIPASTGPMARSANRFLQNRAAIFGLVLLTPLLFAVLTYPLWLPYKPNDIDLMAMNSAPSWKHWFGTDGVGRDVFARTMEGGRISLLVAVSSVVLSTAIGFLIGAISALGGRWADAIAMRSVDLAMTLPPVIFLLVLASIIGSGIWSTVVVIALLSWPVLSRMIRARLLELREREFVMASRGMGAGLGHLLFRHGLPNSIDILVVYATLQVANAILLEAGLSFLGLGVPPPAASWGNMLNAARSTAVLEQFPWQWLFPGGALVLAVLAINFIGDGLRDAFDPRAELN
What is the function of this protein?
Probably part of an ABC transporter complex that could be involved in peptide import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Putative peptide permease protein BRA0407/BS1330_II0404.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLNA_PYRAB
Sequence: MNVSEVKSGATRSPKFVQLIFVDINGMPKGMEIPASRLQEAIEDGISFDGSSVPGFQGIEDSDLIFKADPDTYVEVPWDNVARVYGYIYKDGKPYGADPRGVLKRVIEKLAEMGIKAYIGPEPEFYLFKKNGSWELEIPDVGGYFDILTLDKAKDIKREIAEYMPSFGLVPEVLHHEVGKAQHEIDFRYDEALKTADNIISFKYIVKAVAEVHGLYATFMPKPIYGMPGNGMHLHISLWKEGENIFKGEEGLSETALHFIGGLLKHAKALTAITNPTVNSYKRLVPGYEAPVYISWGYKNRSALIRVPAFWGNGARIEYRCPDPSANPYFAFAAILMAGLDGIKHKVEPFAYVEENVYEMDEGKRKELGIDTLPGSLGEALDELEKDKVVREALGEAYKNFIEYKRKEWESYLEYLEAKHLPKDTKRVTEWELERYFFI
What is the function of this protein?
Probably involved in nitrogen metabolism via ammonium assimilation.  Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_PARXL
Sequence: MTAATQFDQVSIIKRANVYFDGKCVSHTVVFPDGSRKTLGVILPGALNFGTDAAELMEVQAGQCRIRLEGSEDWKTYGAGESFSVPGNSRFDIDVVETLDYVCSYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: GPR_BACC3
Sequence: MKEPLDLSKYSVRTDLAVEAHQMLQERQEEQQQGIQGVIVKEREEEGIIITKVTIDEVASESMGKKPGNYLTLEVQGIRQQDTELQQKVERIFAKEFSYFLEEVGVTKEASCLIVGLGNWNVTPDALGPIVVENVLVTRHLFQLQPESVEEGFRPVSAIRPGVMGITGIETSDVIYGIIEKTKPDFVIAIDALAARSIERVNSTIQISDTGIHPGSGVGNKRKELSKETLGIPVIAIGVPTVVDAVSITSDTIDFILKHFGREMKEGNKPSRSLLPAGFTFGEKKKLTEEDMPDEKSRNMFLGAVGTLEDEEKRKLIYEVLSPLGHNLMVTPKEVDAFIEDMANVIASGLNAALHHQIDQDNTGAYTH
What is the function of this protein?
Initiates the rapid degradation of small, acid-soluble proteins during spore germination.
What are the official names of this protein?
Germination protease, GPR endopeptidase, Germination proteinase, Spore protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase A25 family.
Protein: SPART_BOVIN
Sequence: MEQGPQDGEPIEIKIIKEAYKKAFVFVNKGLNTDELGQKEEAKNYYKQGIGHLLRGISISSTDPEYTGPEWESARQMQQKMKETLQNVRTRLEILEKGLATSLRNDLQEVPKLYPEFPPKDMSEKSPEPQSLSSLPQHSEVNGSTSTASAESSSTPTTLSLPCQSHPSEAPPAYTPQAAEGHYTVSYGTESGEFSSVGENFYRNHSQPPPLETLGLDADELILIPNGVQIFFVNPAGEVSAPSYPGYLRIVRFLDNSLDTFLNRPPGFLQVCDWLYPLVPDRSPVLKCTVGAYMFPDTMLQASGCFVGVVLSSELPEDDRELFEDLLRQMSDLRLQTNWDRAEGENEFQIPGISGSASDQLKEASGTDVRQLDPSSKDVRQKGKRGKKTKGTSSEEVNLSHIVPCEPVSEEKAKELPEWSEKVAHNILSGASWVSWGLVKGAEFTGKAIQKGASKLRERIQPEEKPVEVSPAVTKGLYMAKQATGGAAKVSQFLVDGVCTVANCVGKELAPHVKKHGSKLVPESLKKDRNGKSTLDGAMVVAASSVQGFSTVWQGLECAAKCIVNNVSAETVQTVRYKYGHTAGEATHNAVDSAINVGVTAYNIDNIGIKAMVKKTAKQTGHTLLEDYKIIDNSKGENPGGGASANLKGEKDEQKEGPEKNGAKKKDK
What is the function of this protein?
May be implicated in endosomal trafficking, or microtubule dynamics, or both.  Participates in cytokinesis.
What are the official names of this protein?
Spartin.
What are the subcellular locations of this protein?
Cytoplasm. Midbody. Note=Transiently associated with endosomes. Colocalized with IST1 to the ends of Flemming bodies during cytokinesis.
Protein: CLAP3_CAEBR
Sequence: MTSRIQPKSGGYLLSKSDFTKVFEDVPKIAITSSVDLRNKFDNVKTILSNTSEDWNKRQTQLKTIRSLIINGEKLVDRPTMIAHILQLLGCFELAVKDLRSQILREAAITCSFIVSKYGIETHSIGEDILIPAMGQVAVSTKIMATSASTLTEFIVEYIQTRQVFTILSSFSTSKDKNQRRQLAVLLEIIIGKWSDRLKKQIIRQICELVKSAINDADSETRAAGRRAFAKLEEFHSEEADALFLELENSKQKMLRGGDAASSWASINSDKGSIPIRSKLSAGAKGYSNISAKFLAQRSASAIDPKALKVTGPSRLARPLSTKAMVRQDTSPAGSKIPYPNRPGSRTRTSSITSNDSRDTSPTRRHSPLPPDTQKARVKYGNGSFFAKLGMSDNTDDDEFLLPIRVRSPQKPNLGDSPADNVSRVLKECCSSSVTEKKDGIKKLLPIVSDTTLSSTEIKNIGNCLNRLLSDASNTKLILQMVLEVYAVFIRTHSSRLSEWLRLALAKLFARKATETLPNTKKQINHTLNVILECFNAHHQLVTVCELMCDPIHLMVPKARVALLEYMTSLLDEYTEPGASINHKELKAALRKMFTWIGDQRQSILLTPYIEKAICSMFCVNVADFSALISEFDSDQKAWLHQTLQLNGLENGISSGSGGSGNNHPKATPLRETPHKNDSVVLPEFGSAQKRTAINLGSFNTSTNAALSKLEEQSTSRLMEKMNLNSTVTLPPDTLEKIQNVQDLLHKMRVSKDPDEQENAISQVYMKICDGGFGIWEQCYAKLLLNLFEILSTSRSENNKKMCLRILGKMCTAQAAKLFDSTEMAVCKVLDAAVNTNDATTALAVDDCLRTLATHLPLANIINIAKVILIQEPIDDERASLVLKMVTRLFEELPADELKNVVDDITPCVIKAYQSTSSSVRKTVVYCLVAMVNRVGEQRMAPHFTKLPKAMTNLIQVYVNRAISTSLPRL
What is the function of this protein?
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules.
What are the official names of this protein?
Protein CLASP-3.
What is the protein family that this protein belongs to?
Belongs to the CLASP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GLYA_STAA3
Sequence: MSYITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFVDVTESIAIDRAKALFGAEHVNVQPHSGSQANMAVYLVALGMGDTVLGMNLSHGGHLTHGAPVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMILCKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKIISLALKNSKDEEKLQQAKERVAKLTAEYPLYQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KIT_TAKRU
Sequence: MEYHWILLCVSLCFTFHPGDTKPTITPAGTYVVVSLNAPLELQCQGEKAMQWQREERPKVRGETKVDGKSTLYIPKAHPAHMGRYICLEETSQERASIYIYVKDPDNPFRKSMVSNILSREGDSASIPCLATDPSLENLQLKTCSSKALASGLHFSPSLEQGIIIHNTQKSYEGCYVCTGRLKETNVRSHDYHLTVRPVPVAPPVIMMQAPKRVILIRDESLYLTCNTTNVNGNIKLKWVAPLGSQPAKVDGSSRILTENFTQARSATLHIAAVRIQDTGRYQCEAENEKGVSTQSVWLDVFEKGFMYSNPVNNGTIQVRAGESLLLSVSIEAYPMPRSASWSFMGRGLHNTSDHVITTRSHEYTYSSELKLVRLKMSEGGVYTFQASNGDASVNHTFTIFVISKPEIVSHEGPVDGQVRCVAEGFPAPQITWYYCEQPYARCSQQVNATQEEQNVITVTLFSPLFGKTEVESRVNISRGRFSTLECVATVEGEQAFTLFSISERTISHDLFSPLLIGSVSAACILCLILIVLFYKYMQKPKYQIQWKVIEGIHGNNYVYIDPTQLPYDHQWEFPRKNLRFGKTLGSGAFGKVVEATAYGLANEDSMMTVAVKMLKSSAHSTEKEALMSELKVLIYLGNHINIVNLLGACTVGGPTLVITEYCCFGDLLNFLRRKRESFICFKLEEDCHYRNIMLQREMAGDSLNGYMTMRPSAAGKPSSSSSSEKRRSLREGSPYVEEDSESEMFDEDSLSLDTEDLLSFSYQVAKGMEFLTSKNCIHRDLAARNILLTQGRVAKICDFGLARDINTDSNYVVKGNARLPVKWMSPESIFECVYTFESDVWSYGILLWEIFSLGNSPYPGMPVDAKFYKLIKEGYRMDAPEFAPSEMYQIMRSCWDADPLNRPPFRKVVERIEQQLSDTTKHIYLNFSSRVPVMPRGREESSTHSMASQPFNSAGNNSPPSRPLLLHHEVFLEGTEPFRVQRV
What is the function of this protein?
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine kitlg/scf and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.
What are the official names of this protein?
Mast/stem cell growth factor receptor Kit, SCFR, Tyrosine-protein kinase kit.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MIEN1_MOUSE
Sequence: MSGEPAPVSVVPPPGEVEAGSGVHIVVEYCKPCGFEATYLELASAVKEEYPGIEIESRLGGTGAFEIEINGQLVFSKLENGGFPYEKDLMEAIRRASNGEPVEKITNSRPPCVIL
What is the function of this protein?
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells.  Plays a role in regulation of apoptosis, possibly through control of CASP3.  May be involved in a redox-related process (By similarity).
What are the official names of this protein?
Migration and invasion enhancer 1.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions (By similarity).
Protein: LYSX_GORB4
Sequence: MALDTPSSDLPVSTDDTAEHQPTPAHRPPSAADRRSVDLLEKIRRPRGFGAGAPKIAGTVVGVLAGIALLSSIFPLFRRLIHYPRDFIDNYIVSLPNTSLAWAFVLALVAIALSSRKRIAWWIATIYLVLFMVSNALLLVDPVATDFGVDTDERIQIWIGLGIDAAALIFLIVTYRQFYTRVRRGALFRALGVLIVGLTAATLVGWGLVWAWPGSLERTERLPYAFNRVVTFGSIDSRTFDGHHTHIVIDSALGLLGALALIAAATVLFRSQRLESLMTSDDEKLIRALITRFNDDDSLAYFSTRRDKAVVFSPDGRAAITYRVEIGVGLAGGDPIGDPESWPDAIAEFLTLCDRYGWHPAAMGSSARGAAAYDAAGFGSLSIGDEAILHTREYTISGPAMKAVRQAVTRTRRAGVTVRIRRHGEVPDDEMPQVIARADAWRDTDEERGFAMALSRLGDRADDDCLLVEAVEHAGTPEEKVIGMLSFVPWGRRGVSLDVMRRDRGSVNGVVETMVTELCRNSEQFGITEISLNFATFRAFFEQGPQIGAGPIMRLGYSVLMFGSRFFQMESLYKSNAKYLPDWQPRFLCFEDNRILPRVGLAAIVTEGFVQLPRFGRKQHYIAGQSSIPAGVDADALIAQLESEEDRTAVEVHRPEQVRVRVAKLDRLIEEGFDPYPPADAPTHTIAEAIAEPEGTQVTIAGRVTKMRDFGKVTFADVHDWSGQIQMLVEASRVIPGTPDFGSDVDLGDLVEARGVIGRSRSGELSVLIDAWRFNGKCLRPLPDKWSGLTDPEARVRQRYVDLAINPRSRELLATRSVVVKALRDFLADRGFMEVETPILQQIHGGANATPFQTHINAYNLDLYLRIAPELYLKRLCVGGVEKVFEIGRNFRNEGVDFSHNPEFTSLEAYAAHSDYLKMLDLTREMIQHAATAAHGEPVIIRVDDEGNEQRVDISGDWPVRTVHEVVSEGAGVEITSDTEVSELRGICDRLEIAYRPDWDAGQIVLELYEHLGEDRTTVPTFYTDFPTSTSPLTRAHRSKPGVAERWDLVAWGVELGTAYTELTDPVEQRKRLTAQSILAADGDPEAMELDEDFLTALEYAMPPTGGLGVGVDRVVMLITGQSIRESLAFPMVKPTDA
What is the function of this protein?
Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge.  LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M. tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.