PharMolix/UniProtQA huggingface dataset:
Protein: MMM1_CANGA
Sequence: MVSALEVKSIKDSNETLISLDDYIRNTLPSQLHEILLEEFQNQDFSRGQDVSNSTHDQMIDHTLELTSDLLRNALDKQLMEVQSRTLPVRQSNQLISWSFAQGLIIGQLSVVIFLIFFVKFFIFTDASSKMDNPLPSKVSKSYLKNRRESSSIKDKRKGVLVKEESGETDLHGSLQLNDILEKTYYNVDTHSAESLDWFNVLLAQMIQQFREEAWHKDNILTSLDSFIQKRSSDLPDYLDKITITELDIGEDFPIFSNCRIQYAPNSSDKKLEAKIDIDLNDKITFGMSTRLLLNYPKKCTAALPIDLAVSMVRFQACLTVSLITAEELEFTTGNKIDDNEKNGYYLVFSFTPEYKIDFDIKSLIGARSKLENIPKISNIIEYNIKKWFAERCVEPRFQSVKLPGMWPRSKNTREEVIHKTEDESSKTPHS
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: ATPB_GEOSL
Sequence: MSQNFGKISQVIGAVIDVEFEPGKLPPIYNALRVTNPAIDDKEYNLVLEVAQHLGENAVRTIAMDSTDGLVRGQAVLDTGKQISVPVGRKTLGRILNVIGEPVDEMGPVNAEKEYGIHREAPAFVDQSTKVEAFTTGIKVVDLLAPYARGGKIGLFGGAGVGKTVLIMELINNIAKQHGGFSVFAGVGERTREGNDLWMEMKESGVLDKAALVYGQMNEPPGARARVALSALSIAEYFRDEEGQNVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGELQERITSTTKGSITSVQAIYVPADDLTDPAPATAFAHLDATTVLSRQIAELGIYPAVDPLDSTSRILDPQVIGEEHYSIARQVQYVLQKYKDLQDIIAILGMDELSEEDKLVVARARKIQRFLSQPFHVAEAFTGSPGKYVELKDTIKGFQEIVAGKHDDVPEQAFYMVGTIEEALEKAKKLAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LPLT_ECOSE
Sequence: MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLNAQFYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLADWHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGETRFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVMGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMIGIPVVPIGIGFGALFALAITALWIWQRRH
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRS10_HUMAN
Sequence: MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4, Proteasome 26S subunit ATPase 6, Proteasome subunit p42.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CNTFR_MOUSE
Sequence: MAASVPWACCAVLAAAAAAVYTQKHSPQEAPHVQYERLGADVTLPCGTASWDAAVTWRVNGTDLAPDLLNGSQLILRSLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNTTAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHATPWTEEPRHLTTEAQAPETTTSTTSSLAPPPTTKICDPGELGSGGGPSILFLTSVPVTLVLAAAAATANNLLI
What is the function of this protein?
Binds to CNTF.  The alpha subunit provides the receptor specificity (By similarity).
What are the official names of this protein?
Ciliary neurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha, CNTFR-alpha.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: SOTC_BACTN
Sequence: MKKFTCVQDIGDLKSALAEAFEIQKDRFKYVELGRNKTLMMIFFNSSLRTRLSTQKAALNLGMNVMVLDINQGAWKLETERGVIMDGDKPEHLLEAIPVMGCYCDIIGVRSFARFEDRDFDYQETILNQFIQYSGRPVFSMEAATRHPLQSFADLITIEEYKKTARPKVVMTWAPHPRPLPQAVPNSFAEWMNATDYDFVITHPEGYELAPQFVGNAKVEYDQMKAFEGADFIYAKNWAAYTGDNYGQILSKDREWTVSDRQMAVTNNAFFMHCLPVRRNMIVTDDVIESPQSIVIPEAANREISATVVLKRLIEGLE
What is the function of this protein?
Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline.  Is essential for arginine biosynthesis.  Has no activity with either L-ornithine or L-aspartate as substrate.  Has also no detectable AOTCase activity, being unable to convert N(2)-acetyl-L-ornithine to N(2)-acetyl-L-citrulline.
What are the official names of this protein?
N-succinylornithine carbamoyltransferase, N-succinyl-L-ornithine transcarbamylase, SOTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
Protein: POL_CSVMV
Sequence: MNKITYMTIKISIPKYMSRIYHGLFDTGANICICKKKVLPDELWHKTENLVLRGFNDEKHVAEYRADNITIMIAKEKFIIPYIYAMDEMSPDIIIGATFYNKYSPIELDIGKGIIKFTKNNEKYPNYLVKYPKKRKLVPWTKGNPSVTETMENIGINQIESRNPIEEEINQILGTDIYGENPLEKWEKHKTLAKIELKNETDNIYKPPMLYQETDLPEFKMHIEEMIKEGFIEEKTNFEDKKYSSPAFIVNKHSEQKRGKTRMVIDYKDLNKKAKVVKYPIPNKDTLIHRSIQARYYSKFDCKSGFYHIKLEEDSKKYTAFTVPQGYYQWKVLPFGYHNSPSIFQQFMDRIFRPYYDFIIVYIDDILVFSKTIEEHKIHIAKFRDITLANGLIISKKKTELCKEKIDFLGVQIEQGGIELQPHIINKILEKHTKIKNKTELQSILGLLNQIRHFIPHLAQILLPIQKKLKIKDEEIWTWTKEDEEKIKLIQDYSKNLVIKMKYPINKEDMNWIIEVDASNNAYGSCLKYKPKNSKIEYLCRYNSGTFKENEQKYDINRKELIAVYQGLQSYSLFTCEGNKLVRTDNSQVYYWIKNDTNKKSIEFRNIKYLLAKIAVYNFEIQLIDGKTNIIADYLSRYNSSDTDGRYDEANT
What is the function of this protein?
Encodes for at least two polypeptides: protease (PR) and reverse transcriptase (RT).  The protease processes the polyprotein in cis.  Reverse transcriptase is multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated, and reverse-transcribed inside the nucleocapsid.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA) (By similarity).
What are the official names of this protein?
Putative enzymatic polyprotein.
Protein: EIS1_YEAS8
Sequence: MSLISAVEDRDIHNIGKTSGGGSRTSSITSSKKSLKHGSKSLRKPKVYQTTGELLSREALYKAKLKYGVYQSPAQSYSIGVSDAHAASDKAANLAHDNQTTVEAYKRMFIDPNATKAASKMGPKVVRNNSITSATSKTSKESQTKRKSKESPGAAASKAYSMTMETTSLSSQTNSRSYSITSASSVLSGASGSFNSTVNPKPKTLNLEKVLVGAEKKAESRIKERWEPEKTNFQYGVKTDEHGNLNQFSFSNEMMNNIMAKVDAPKAQDLQKVKKVSAEKEAKSMKFALGAANAVKDMHPGEDIDKSIALKAQKRETYLSQLTSQQVLTLARANVDRQLDIIEKSDMHRKLFTNMEYNKAAVAVAQSNHQKKTEFHNKINMGGGLFLSPEDITKIASGLISPVLGEVSERAEAQRAMDEEIAERTEAYNKSLNEWETMERSIISNDAKVLTTTANRHQTEKKTSQEKIKASFDALVARMDTKVAERETLLEDTKSKEIEFKKQMQQELKDEKARLDQDLEEWGKKCEQDITEARKEQEELLKPYHDDLANAEAEHKTLVEERDAINAEISRLQDAIVDHKRKISGYGNDLDAQKNRNIREDDKLLELGQTKESLESHLNDDVIILANKAKEQAELSTKEARLKQLEVDSLINERKSELNATDIELKKEKLSLLEAMKDVASARGDDKIDEEKVKKLIGMTSEEYLTQNKSVEKNVEDLPTQLEKIEEGDELKKEEIVGAETKNSGGDGVPVSTAAKEATETSSAVQTKEPEEKISIGNKSSGKEDANDCKSAEHSKEISVSQKAGNNKSLGVSPDSLEHTFSGFSQGSSIEDDQDAISNQEKK
What is the function of this protein?
Required for normal formation of eisosomes, large cytoplasmic protein assemblies that localize to specialized domains on plasma membrane and mark the site of endocytosis.
What are the official names of this protein?
Eisosome protein 1.
What is the protein family that this protein belongs to?
Belongs to the EIS1 family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes at the eisosomes.
Protein: DCDA_MYCS2
Sequence: MNAHPAGPRHAEELHHADVPDKPQSPDEIMLLAPNVWPRNLVRGADGVVTIAGVPVTDLAAKFGTPLFVIDEDDFRTRCRDIAAAFGGGQYVHYAAKAFLCSEIARWVDEEGLSLDVATGGELAVALHAGFPASRITVHGNNKSVAELTAAVQAGVGHVVLDSEIEIERLDQIAGAAGVVQDVLVRVTVGVEAHTHEFISTAHEDQKFGLSLATGAAMNAIRRVFATDNLRLVGLHSHIGSQIFDVAGFEIAAHRVIGLLRDVVAEFGVEKTSQMSIVDLGGGLGISYLPHDDPPPMKELADKLLEIVRTESAAVGLPTPKLVVEPGRAIAGPGTITLYEVGTVKDVAVSQTAHRRYVSVDGGMSDNIRTSLYAAQYDARLVSRVSDAPPALARIVGKHCESGDIVVRDTWVSDDIAPGDLIGVAATGAYCYSMSSRYNLLCRPAVVAVADGQARLVLRRETVEDLLSLEVKGQ
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: FCSB_DICDI
Sequence: MINNWLAVGLLVVSGILAFNWKRKHPYGQTVEIGEKPENGGRIRRNSACADHLISFLEDDEIYTLYDSLVKSCKKYGERKCFGERKKDSNGNLGKFEWISYNTYLERCEYIQQGLCELGLKPKSKVGIFSKNRLEWLIVHSASFIQSYCVVSFYETLGVESLSYVTEHAEIGLAFCSAETLQKTLDIAKGVKVLKTIICFDSIDKEHYNIAKELGVTLYTYDEIMKKGKEANGKHKHTPPTPDTLSTIMYTSGTTGPPKGVMITHKNLTSVVCAVSDFIKVYDTDVHYSYLPYAHVLERVVILAAFHFGAAIGIFSGDISNILVEVKLLSPTLFIGVPRVFERIKTNVFKEISKKPALLRTLFNGAYNLKYLSIQHGFKLPIIEKVLDLVFFSKIKQALGGKVRVILSGSAPLSFDTEVFLRVVMCCCVLQGYGASEGCGGDACKRLDDESVGTIGPPFASNEIKLVDVPELGYDSNGEVQTGEVCLRGPSISSGYYKDEEKTREEFKDGWFHTGDIGRWNRDGSLSIVDRKKNIFKLSQGEYVAVEKIETIVVKSEYVEQVCIYGDSQKSCVIAIIHPHPESCSEWAGSKKTDKDIKEICKNQDFIKVVLDDIIKNCKKSGLHGFEIPKAIHLTPEAFSDQNNLLTPSFKLKRHEIKKYFEDEIKKLYSKLD
What is the function of this protein?
Long chain fatty acid acyl-CoA synthetases catalyze the formation of a thiester bond between a free fatty acid and coenzyme A during fatty acid metabolic process.
What are the official names of this protein?
Fatty acyl-CoA synthetase B, Long chain fatty acyl coenzyme A-synthetase 2, LC-FACS 2, Long-chain-fatty-acid--CoA synthetase 2.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: NUOK_BURPS
Sequence: MLTLAHYLVLGAILFAIAIVGIFLNRRNIIIILMAIELMLLAVNTNFVAFSHYLGDVHGQIFVFFVLTVAAAEAAIGLAILVTLFRKLDTINVEDLDQLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYSG_SHIDS
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHDMPGEMPVAIVENGTAVTQRVIDGTLTQLGKLAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: AROE_CORGL
Sequence: MNDSILLGLIGQGLDLSRTPAMHEAEGLAQGRATVYRRIDTLGSRASGQDLKTLLDAALYLGFNGLNITHPYKQAVLPLLDEVSEQATQLGAVNTVVIDATGHTTGHNTDVSGFGRGMEEGLPNAKLDSVVQVGAGGVGNAVAYALVTHGVQKLQVADLDTSRAQALADVINNAVGREAVVGVDARGIEDVIAAADGVVNATPMGMPAHPGTAFDVSCLTKDHWVGDVVYMPIETELLKAARALGCETLDGTRMAIHQAVDAFRLFTGLEPDVSRMRETFLSL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids, and plays a key role in the quinate degradation pathway.  Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively.  It can only use NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase (NAD(+)), QSDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: PFF1_YEAST
Sequence: MKLKSVFRSVLKYRKTNLSLLLLITYSIITLLYIFDHERYKLNLPKEDEHPEFNDLLETAWGDLQIITASFHPYTSKENDKVHDYLLKRVLEITGNSSFASVSDDKESERSILFQQQDPFNESSRFSRVTYFESSNILVKLEGKNPEEEGLLLSAHFDSVPTGYGATDDGMGVVSLLANLKYHIKHRPNRTLIFNFNNNEEFGLLGASTYFDHSWSNLTKYVINLEGTGAGGKAVLFRTSDTSTARIYQQSVKENPFGNSIYQQGFYSRYVRSETDYKIYEENGMRGWDVAFYKPRNLYHTIKDSIQYTSKASLWHMLHTSLQLSAYVASNSLDTADQTPACYFDFIGLKFFVISAKTLFYWNCIFLLVSPVVAIGLYLISRDRMTWKSYSWLSWTRFPLSLAAGIIVQKLFSNDIIRSNPLTFSRNYFWPISAFFTQVIFTSYVLINCSNFFFPCADMKSLSIIELFIILWTILLFTSKLLYSSDYRYTGLYPLSIFFLLSTIAAILRLLALALGMRTRKRLGRECRDHHSNYSSHSQIDMERDGQENLEQPQDQLTSSQDDQASIQDDNVSTTSAGPSHNVDEDHGMDSSSQQHDERVPLLKGSNSMEEGLSTRENSLKLEYTDYAWIIQFLLIVPIPSFILFNSVDVIMDALNHTVQEGSKATFDVLRFGMVGSILIALPILPFFYKVNYITISLTALLFLISASKTLLVHPFTNSNPLKVRFSQNIDLSQGNAASVHVLGREGNFLKPMLQDLPSIKYSSTHINCTSVTNGMELCMYDGMQPNLLSTNGNTNISSMVKVHVLHNNRNSTERSPYEPIVAELLLEVKENRACTLTFESRHQAKSPVREITVYQKKNSAPQKANITKTIKSASGINELQLHKLDFDQETYHIGVQWFPKLLTDGNVEDDKLGTKDELSVSISCYWGEYDSESVVNGTAVRKIPAFDELINYAPLSFSFTNEQKGLVIVKDAIIL
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: LECG_PATPE
Sequence: MAFFRALCFVLLVGFAAACQPDCSWKCPPKCPPMWTFYNGNCYRYFGTGKTYDEAESHCQEFTEVGLGHLASIASAEENNLLLTMWKSVRTTTTGGLWIGLNDQAEEGNFIWTDGSAVTFTDWATTQPDNYQNEDCAHMRHELDGDDRWNDIACSRAFAYVCKMSTTN
What is the function of this protein?
Alpha-N-acetylgalactosamine-specific lectin.  The oligomeric form has Ca(2+)-dependent hemagglutination activity towards sheep erythrocytes.  Its hemagglutination activity is inhibited by various monosaccharides, oligosaccharides and glycopeptides, including inhibition by GalNAc, blood group A trisaccharide, Tn antigen, mucin and asialomucin.
What are the official names of this protein?
Alpha-N-acetylgalactosamine-specific lectin, Alpha-N-acetylgalactosamine-binding lectin, GalNAc-specific lectin, Lectin, ApL, Tn antigen-specific lectin.
Protein: CHO2_CLAL4
Sequence: MSDQRKGITFDGETFTFPETNDMVKTLFDPTVHKSACELIIVTLLVMNSLVFYSVSNNQSRINIFVGMYIFWRLCYNFGIGFLLNQQSNRFRLVKISEKMRLFDKGNKSFWARCVQTEVQSQMGPSYSISAHPVAFNTWLIFRKVVDLILMEDFITFMCVVVACAIDSDYQFLHGQPVWLTTLRLVIGSILIVFNFWVKVNAHNTIKDYAWYWGDFFFRQINNDDLIFDGVFEMFPHPMYSAGYVGYYGFALIAKSYTVLIVAVFGHFLQMVFLHLVENPHIDKIYGPPPNETSLKKLVKLKDLSFFDNVAPLVGLVNFNILRASDIINLLNCLTYAVAIPTVSSLATYNIEAMGKVLFCIAILIKGFESFVINGVLLLQSNYKTISEWYLANNLPVENSLNNFAVLYNSLINLTYSSFVGMNVFKLLTKLKYQDLIITGHIYLRIFLGLLLIITQVMINTSIVDSIGYFGWFYGDFFIPKASVLPQRAHLSKGGVYRYLNNPEQIFGVCGVMGVTMIVPTYDNFMICLLWMLNNFFRINFVERSHMIKIYGEREVSQDSGVMKTVKKHLLPESIQKKFEVSPTNEPKKRTNSVFIESFDSFIKELRSKNTSPVVSKERLAEMSQNEFFSGSDYCLEIEGLEDSSFVPHSFIGEPIEVKFRAPAKHSPKDWVGLYKVAHTSFSRYRTLVSSNNRWDWTGPEEQGTIVFSKEKLFCEEGLYEFRYHLDGKHDVAFISAPFEIKLRHIEVPLESAEADELANQLRKYIFDHVVSGVDDNETPIFVGISQTQDIVATYEHIAMLITKSTGVKVGKRFLIYNDNETGNKFTVGDLASRLINIKKVMHELEGDEYLRIKKLE
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DAPD_KLEP7
Sequence: MQQLQNVIESAFERRADITPANVDTVTREAVNQVIALLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIDGAESRYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYLGQSTKIYDRETGEVFYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAI2_MOUSE
Sequence: MDDLQSQNLSMDMTDSPPTLANNRLENRMAQLITTEAWNINSTDLVKKALVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPNGNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNAIHNNLFQGAEDSEAQPQLLDLRIPSQPQEPALPFEAVLQNLFPTQGSLGPPPCQPPPGYAPVPPQPFNSPLSPLVPPATLLVPYPVIVPLPVPVPIPIPVPVPQSTESKFSPTFPKPPSSFGLHSFKGTQTTLEKDELKPLDILQSKEYFQLSRHTVIKMGSENEALDLSMKSVPWLKAGEASPPVFQEDAALDLSLAAHRKAEAPPETLYNNSGSADIQGHTILEKLSSGMEMPFAPAKCSEASAMMESHSSNSNGTEMVSQPSHPGSELKAENNIEILSESQAAKVIVSVEDAVPAIFCGKIKGLSGVSTKNFSFKREDSVLQGYDINSQGEESLGNAEPLRKPIKNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK
What are the official names of this protein?
Retinoic acid-induced protein 2, 3f8.
Protein: VATB2_BOVIN
Sequence: MALRAMRGIVNGAAPELPVPTSGPLAGSREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVYETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH
What is the function of this protein?
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:32764564).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:32764564).  In renal intercalated cells, can partially compensate the lack of ATP6V1B1 and mediate secretion of protons (H+) into the urine under base-line conditions but not in conditions of acid load (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit B, brain isoform, V-ATPase subunit B 2, Endomembrane proton pump 58 kDa subunit, Vacuolar proton pump subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Apical cell membrane. Melanosome. Cytoplasm. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein.
Protein: ESAA_STAAE
Sequence: MKKKNWIYALIVTLIIIIAIVSMIFFVQTKYGDQSEKGSQSVSNKNNKIHIAIVNEDQPTTYNGKKVELGQAFIKRLANEKNYKFETVTRNVAESGLKNGGYQVMIVIPENFSKLAMQLDAKTPSKISLQYKTAVGQKEEVAKNTEKVVSNVLNDFNKNLVEIYLTSIIDNLHNAQKNVGAIMTREHGVNSKFSNYLLNPINDFPELFTDTLVNSISANKDITKWFQTYNKSLLSANSDTFRVNTDYNVSTLIEKQNSLFDEHNTAMDKMLQDYKSQKDSVELDNYINALKQMDSQIDQQSSMQDTGKEEYKQTVKENLDKLREIIQSQESPFSKGMIEDYRKQLTESLQDELANNKDLQDALNSIKMNNAQFAENLEKQLHDDIVKEPDTDTTFIYNMSKQDFIAAGLNEGEANKYEAIVKEAKRYKNEYNLKKPLAEHINLTDYDNQVAQDTSSLINDGVKVQRTETIKSNDINQLTVATDPHFNFEGDIKINGKKYDIKDQSVQLDTSNKEYKVEVNGVAKLKKDAEKDFLKDKTMHLQLLFGQANRQDEPNDKKATSVVDVTLNHNLDGRLSKDALSQQLSALSRFDAHYKMYTDTKGREDKPFDNKRLIDMMVDQVINDMESFKDDKVAVLHQIDSMEENSDKLIDDILNNKKNTTKNKEDISKLIDQLENVKKTFAEEPQEPKIDKGKNDEFNTMSSNLDKEISRISEKSTQLLSDTQESKSIADSVSGQLNQVDNNVNKLHATGRALGVRANDLNRQMAKNDKDNELFAKEFKKVLQNSKDGDRQNQALKAFMSNPVQKKNLENVLANNGNTDVISPTLFVLLMYLLSMITAYIFYSYERAKGQMNFIKDDYSSKNHLWNNVITSGVIGTTGLVEGLIVGLIAMNKFHVLAGYRAKFILMVILTMMVFVLINTYLLRQVKSIGMFLMIAALGLYFVAMNNLKAAGQGVTNKISPLSYIDNMFFNYLNAEHPIGLVLVILTVLVIIGFVLNMFIKHFKKERLI
What is the function of this protein?
Component of the type VII secretion system (Ess).  Provides together with EssB and other components such as EssC and EssE a secretion platform across the cytoplasmic membrane in the host.
What are the official names of this protein?
Type VII secretion system accessory factor EsaA.
What is the protein family that this protein belongs to?
Belongs to the EsaA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.