PharMolix/UniProtQA huggingface dataset:
Protein: IF1_ROSDO
Sequence: MAKEDTLEFPGVVKELLPNATFRVELENGHEIIAHTAGKMRKNRIRVLAGDKVQVEMTPYDLTKGRINYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIOX2_RAT
Sequence: MPKKVKPTGDENEEESVPCKQVKEELPNTLSVLNFDSPSSFFESLISPIKVETFFKEFWEQKPLLIQRDDPSLAAYYQSLFSLSDLRSLCSQGLYYGRDVNVCRCIGGKKKVLNKDGKAQFLQLRKDFDQKRATIQFHQPQRFKDELWRIQEKLECYFGSLVGSNVYMTPAGSQGLPPHYDDVEVFILQLEGRKRWRLYSPTVPLAREYSVEPEDRIGTPTHDFLLKPGDLLYFPRGTIHQAETPSGLAHSIHLTISTYQNNSWGDYLLDSISGLVFDIAKEDVALRTGMPRRMLMNVETPADVTRKLSGFLRTLADQLEGRKELLSSDMKKDFVMHRLPPFCVGNGTESMNPGGKLPRLNSIVRLQFKDHIVLTVGPDQNQSDEAQQKVVYIYHSLKNERQTHMMGKEVETEIYGLRFPLSYVDALKQIWCGSPVRVKDLKLGTDEEKENLAVSLWTECLVHVL
What is the function of this protein?
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.  Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression.  Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39' (By similarity).  May play an important role in cell growth and survival.  May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
What are the official names of this protein?
Ribosomal oxygenase 2, Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, Histone lysine demethylase MINA, MYC-induced nuclear antigen.
What is the protein family that this protein belongs to?
Belongs to the ROX family. MINA53 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: PGK_ALKCK
Sequence: MNKKTLYDYDFAGKTVFCRVDFNVPMKDGKITDETRIQAALPTIKYLSEQGARVLLASHLGRPKGEVVESLRLAPVATRLSELLGKEVQAVQEAHGPVAKQAVEGLEDGGVLLLENVRFYPGEEKNDPELAKAFASLADIFVNDAFGAAHRAHASTEGIAHYLPSAAGFLMEKELDVLGKALSNPERPFTAVIGGAKVKDKIGVIDNLLDKVDNLIIGGGLAYTFVKAQGYEVGKSLLEEDKLDLAKQFMEKAEQKGVKFYMPEDVIVADDFSDDANKKEVAISGIPADWEALDIGPKTRKTYEAVLKASKLVIWNGPMGVFELESFAGGTKAVANALAEASDTYSVIGGGDSAAAVEQFGLADKMSHISTGGGASLEFMEGKELPGVVALSEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSID_SHIBS
Sequence: MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAALFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVLGSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTILLRHILPGTVSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPALAIFLTVLAFNLLGDGLRDALDPKIKG
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATB_HALMA
Sequence: MTAQASEARELAAVIGLEVHVQLETETKIFCGCSTDVADAEPNTHTCPVCLGLPGALPVVNEGAVEAAVKVGKAIDADIPAETTFHRKNYYYPDLPKNFQITQYDSPICQDGELEFSVESERRSVDIRRAHLEEDPGSIKHVREGSGPLESRTCSIERADYTLIDYNRAGTPLMEIVTEPDFRAPGEVRSFLEKLEEVLEYLGVFDATRDGSLRIDANLSLVDASEVGEDGDIDKSVLEDANRTEVKNISSHKGAEQALSFEASRQRKLIQSGRAVEQETRHFNETHGNTVSMRSKEEEKDYRYFREADLPPLRVSHWKDEVPIPELPDARRERFVEEYGLSEEAASKLTSTKQVADFFEDVAERFDANLAATWVADNLLGELNYRDMAITDIDDRFDEVTQLVALVAEDEITAKNAHETVLREMLDTGDDPDTVVDREGLGKTSGDEVQQAVVEAIDENPDAVEDYHSGEGGAINFLVGQVMEKTGGSADPGDVNGLLREELES
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: UBC_HUMAN
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGV
What is the function of this protein?
Exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
What are the official names of this protein?
Polyubiquitin-C.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus. Mitochondrion outer membrane; Peripheral membrane protein.
Protein: SYH_CALS4
Sequence: MLTKAPRGTKDVLPSESYKWQYVENLMREICEFYGYKEIRTPGFEHTELFLRGVGESTDIVRKEMYTFNDRSGRSITLKAEGTSPAVRAFIEHGLYAETQPTKLYYITPVYRYEKPQAGRLREHHQFGVEIFGAKSASADAEVISIAMTLLKKLGLNNLELRINSVGCPVCRKNYNKVLKEFLKEHLDELCDDCKVRYEVNPLRVLDCKVESCRRVTGEAPLITDYLCDDCRNHFEELKKYLDAMGYDYIVDPRIVRGLDYYTKTAFEIISKDIGAQGTVCGGGRYDGLIEECGGPSMPGVGFGMGIERLLLTLEQNGIEIPKPEGPDLFIAYIGDEAKLFTFTLANKLRFNGLKVEIDHMERSLKAQMKYANKLNAKFAVVIGEEELESKKVKLKNMATGEETEILIDEIEKAIKN
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAD_BRANA
Sequence: MALKLNPLASQPYNFPSSARPPISTFRSPKFLCLASSSPALSSKEVESLKKPFTPPKEVHVQVLHSMPPQKIEIFKSMEDWAEQNLLTQLKDVEKSWQPQDFLPDPASDGFEDQVRELRERARELPDDYFVVLVGDMITEEALPTYQTMLNTLDGVRDETGASPTSWAIWTRAWTAEENRHGDLLNKYLYLSGRVDMRQIEKTIQYLIGSGMDPRTENNPYLGFIYTSFQERATFISHGNTARQAKEHGDLKLAQICGTIAADEKRHETAYTKIVEKLFEIDPDGTVMAFADMMRKKISMPAHLMYDGRDESLFDNFSSVAQRLGVYTAKDYADILEFLVGRWKIESLTGLSGEGNKAQEYLCGLTPRIRRLDERAQARAKKGPKVPFSWIHDREVQL
What is the function of this protein?
Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons 9 and 10 of the acyl chain.
What are the official names of this protein?
Stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic, Stearoyl-ACP desaturase, Acyl-[acyl-carrier-protein] desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid. Note=In green tissue, found in chloroplasts. In non-photosynthetic tissue, found in plastids.
Protein: MNMA_CHRVO
Sequence: MDEGIRASGGIRACQTGKQKQGRKRPVTGKKRIVVGMSGGVDSSVTAWLLKQQGHEVIGVFMQNWEDDNDDEYCSIKQDALDAMSVADIVGIDMEIVNFAKEYKDRVFSYFLKEYSAGRTPNPDVLCNAEIKFKAFLDYAMELGADCIATGHYARKLEQDGTHYLMKAVDHTKDQSYFLYRLQQHQLAKAIFPLGDIRKTEVRRLAEEAGLPTAAKKDSTGICFIGERPFREFLQRYLPTSPGQMVTPDGKVVGEHIGLMYYTLGQRKGLTIGGSRDGNGEPWFVAGKDIPGNKLIVVQGHDHPLLLKPTLSMADLSWTLPDAPAPGEYSAKNRYRMADAACTLSPIVDGQASLTFQEKQWAVTPGQSAVLYHGDICLGGGIIQ
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KIF7_DANRE
Sequence: MSPKGVGHSKVEESAVQVAVRVRPLLPKEILHSHESCITSDPEERRVTLGNDRHFHCDFVFEDGSTQEEVYTNCVQPLIEAFFHGFNATVSAYGQTGSGKTYTIGEASISAFRDDEQGIIPRAVAEIFKLLDENDLIDFSVRVSYMEVYKEVFRDLLEVETASKDIHIREDERGNVVLCGVKECEVEGLDEVLSLLESGKTARHTGATQMNPHSSRSHTIFTVLMEQRRGGSRAANGSVQILSSKFHFVDLAGSERILKTGNTGERLKESIQINSGLLVLGNVIGALGDPKRKGTHIPYRDSKITRILKDSLGGNAKTLMIACISPSSSDFDESLNTLNYAKRARNIQNRATVNCRGEPDRIEGLELQIKALRRALENRQRSETRIIARSDPEKRLRPFEVDVRKLQAESAHYRTCTDSAYRLLTELQGEGTLNAGQILRVKEWLCGVEEERSGLTSASGLDSGIESSSTEDSTALKRRQAVLNNQDLVKEDWRGEREDYTSQLQAQIQQLEQENTDFLVALEDAMEQYKQQSDKLQEQQDLIAELHSLLAQPGGAGFLHLKQRPHTAPINSLLQTPDRLTPPCDSDVGRSLARQLDVGASVDSSSYSEQTQWDGTHGNTHCESSRKLNRDEDGHMQTTRDKRKSINVTWTKKDIAIPQGPFGGTRTALPQTLGLCHPLGMQFNRRTSNSSIGESSVWESVRGFGGEFCSDRGLLQAQQKIRELSITIRMKEELIKELVKTGKDAQAMNRQYSRKISELEAEAEQARVELTEAQKQLQELEVQGGRDAVDRSKAQECRRKIAAAQSKVQVLKQKQRDTAQLASLSAQSERRVQELERNVQNMKQQQDLLQRRLREESQQKRRLETEMQKGKHRVKELEIKNEQQQKILRIKTEEIAAFQRQRRSGSNGSVVSLEEQQKIEEQKRWLDEEMEKVLDQRRGLEDLEGELTKREEILAKKEALLWERSGLESKKLRSSQALSQDLLTLSSRIESLERELTERNGLLRSGSAQDSQQIRQEISNLRQEKELLLKQRVELDDKLRQGNLLSPEEERTLFQLDEAIEALDAAIEYKNEAITQRQRQLRASGSMLTQWEMNLMAKLTYLSASETRALLCKYFDKVVSLREEERRLQMALAELELRVEEQQNLVGWLEAALERQQLEADRRLTQQQKEHERNIQLLLQQCREQMDEGLAGRLRQYEGLIHNLSKELNFCKIANQELNIKLREMCGPVNLTGEQCKGLNCDSLLLAGAQSRVAEDVKPIIDAERVQKSREEMREPVNAPLPATWRRSSLPTEDQYTMEELRQRAACELPNNRIVQPGMNSTHWSGSTSLPVTRPRREPRRSSLNTAPLYSSSAIIDVRRNPV
What is the function of this protein?
Acts downstream of smo as an intracellular repressor of hedgehog signaling pathway, mainly through the suppression of gli1 activity.  This negative regulatory effect is enhanced in conjunction with the suppressor of fused (sufu) protein.  Positively regulates gli2a activity by promoting its dissociation from sufu.  Involved in the regulation of microtubular dynamics.
What are the official names of this protein?
Kinesin-like protein kif7, Kinesin-like protein costal2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF27 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium.
Protein: STN1_LITCT
Sequence: MKEPPSLLWGLDPVFLSHARLYIKDILELKESNQVPGIFFYKDHPIKQVDILGTVVCVREKDAFYSYGDVHRSTSGANDLDGLVQELHRQESSKAKMEIGDVIRVRGYIKVFRMQREVVASIFYKVDDPTLDMQIMRMLELPYLYKHAYDKPFILPEDMTNQSQEQPNQAVLQRSGLISLLSEKIMNFVKENTIYNFYLPELESMPSLLSEATNPHYITESDSNVSSSSREIRSLFKEAIHILLKRGIVYQKGQNKDVYYVTDHDKELHKLTLNMIKQDCSRQGHAEKGCHFLHILNCVQQDFGSCINEAILQRVINALEQNSDIVSTMEKYYTAF
What is the function of this protein?
Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex.  The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves.  Initially the CST complex has been proposed to protect telomeres from DNA degradation.  However, the CST complex has been shown to be involved in several aspects of telomere replication.
What are the official names of this protein?
CST complex subunit STN1, Oligonucleotide/oligosaccharide-binding fold-containing protein 1, Suppressor of cdc thirteen homolog.
What is the protein family that this protein belongs to?
Belongs to the CTC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: GATB_PARP8
Sequence: MATQWEVVIGLETHAQLSTVSKIFSGAATQFGAAPNTQACPVDLALPGVLPVMNKGAVERAIQFGLAIDATIAPRSIFARKNYFYPDLPKGYQISQYEIPVVQGGQITIQVPANEKAGKEAYEKTINLTRAHLEEDAGKSLHEDFAGMTGIDLNRAGTPLLEIVTEPEMRSAAEAVAYAKALHGLVVWLGICDGNMQEGSFRCDANVSVRPVGQKEFGTRAEIKNLNSFRFLEEAIQYEVRRQIELIEDGGTVVQETRLYDPDKRETRSMRSKEDAHDYRYFPDPDLMPLVIDASWVERVKGELPELPAAMQKRFVDQYGLTPYDAGVVTAGKAMAAYYEAVVAKVGAAQAKVAANWLMGEVSSQLNREGLDIADSPVSAAQLALVLQRIADGTISNKIAKEIFLAIWEEKATDEAAADRIIEAKGLKQISDTGALEAIIDEVLAANQKSVEEFRAGKEKAFNALIGQAMKATKGKANPQQVNELLKKKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: K1522_DANRE
Sequence: MVVFLSKNVRSLLSIFKKKGQKQDEQRKLTVHYTASQHYQENVFIEGSRPKYLEDLHTEAQEGLKILQQEEEDTSSKERNESLENDSTSGHSIISVSTASAVSTRPVLTRQGSTFKPLNPVKRLDKSKRRSRRTTIMGIPQQVQRELDMARGTMLQQLPNRGHDSEDDSSGTVVLQTIDGDLPSVNHEGARVHLQNIEVLQASRDEDLLLNHIHSVYQDELNRKLGLGACPTQRPKSLAVPGMTTYSFLQEPQGPVMSISPQATYLSKIIPNAVLPAAIDIIEINHDHNRCSASTASKGSMASASPSSSRSGSGTNQAPPTTSPSRSNSQSSETIVSNSSTISSKGKCLPTFDADSAKDISVLIPKDMSVSSSSSWKSSEGKGTNHRLNPREYGDAGDNVRNSHSFSRSLSVMKTKLPPAPPQRTYSLHHENMQRQREQGDIQDPKDVAPNNNEQTNRDISSTKENHQSAKNKKSSVHSLELRSDFHTTVKSSPLSPDQVFTGRHARSGNSSPQKTRECGENFDRTLSPSSGYSSQSGTPTHSPKEVSPSSPGKRRVKPSKPERVCAKTSPVVSVSSSLTSLSSVISDTAHQDIQTNTTSSEPLKFSPPLTTVKNKVTPTHQTIALRTLFNIPPPPKVKAPSPPPPETWVQNKQTLELLCGPGPNIHKLESLISKTQNKNSMQINEQVIPKTQTTEETKTENTVVKELTKSASPQVHKQMMVEPPDVRHTEKSILHNELKSPETLAKVNQIPHTQDEKTIEDQKDRWSQTLPTTNVPSIIVDQSMLSQTNSIEKTKAATVSSNENQRNCIVTDIVNRISVQTLNIEVPEVNGVSPPPSPPPEHHPPPPPIKKMSDMSVSIPPSEKEEQKQVEQVTFPESSWPPPPPPMEESTELMFEEQDELDFPPPPPSFIHEPMSEISDDFHEESCEEVSIKLLSTNVSDMDSSPEQDSERHTILPKRIVQNSVEVRQQDKSSDSVSEFLEDQAEIENTNVASTIISSHLPDKNLHEKETLVSTSIPLAPPLPVEEQSTINFRKQLSFVDKDNRSKELLCRHKSTPIPKEDANIPLVTPSLLQMVRLRSVNVGEDQVNNDSKPSTEPTTNEDHSISSQVTPQKPIRRSLTLKSNSPAKSSSASSAVPSMCLQEAIRMKTAAMSCSGVPAMLNLRSSSGSSATSPVPSPKSPDGCDLLMSPASTASFIFSKSTKRVVIETPTSPDVQASLKQSLAAEIMQVSDQAKTMITNGTKKPIKVPPPVAKKPVHGSNPPNKMENATQDKTEILTNKQIMRVDVNGQSDQVHPAGQRAQSLGNQEQASKEAFAMNMSICA
What are the official names of this protein?
Uncharacterized protein KIAA1522 homolog.
Protein: Y926_STRP8
Sequence: MKLAVITDSTATLPIDLKQDKAIFSLDIPVIIDDETYFEGRNLSIDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDRTTAFIMVDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPRL
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein spyM18_0926.
Protein: Y5279_BACC1
Sequence: MHVPIRLLEWFKVEQTLVIQKKKRFGFSQGIGITLLIAIVAKYLAELPFLNIMGQLVIAILIGMVWRAAIGVPHDAIAGTNFASKKLLRFGIILLGMRLNLVDIAKAGPKVLVIAAVVITFTIFVVYGLTKVFKVEKKLGILTACGTAICGAAAVVAIAPQVKAKDDETAVGAAIIAILGTIFTLIYTLLYPVLGLSPYGYGVFSGATLHEIAHVIAAAAPGGSAAVDIAVIVKLTRVAMLVPVAILIGLWFGKSEGSKEKRSWRDLPIPWFIFGFLAMSAVHSLGIIPEVVAGYIVVIAYMLIAMAMAGLGLNVEFKTFRKLGSKAFVAGLIGSVCLSVLGYVLVYALGFM
What are the official names of this protein?
UPF0324 membrane protein BCE_5279.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREF_MARN8
Sequence: MATNTPTEPGGDLALLGLMQLVSPALPIGAFAWSQGLESAFELGWVNNEAELAQWIEGVLEDGLSRCELPLLARLQTAWANDDGATIAHWNQWLHATRETAELSDEDTRLGGALKTLLGNLNLLPDQTLIPAEPGYITLFAWAAQVRRVPVRQTLLGFAWAWLENQLAVACKALPLGHTAAQRIIEQLRPALVNATDQALARQDHELGPILPGLALGSALHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBX2_MOUSE
Sequence: MADVEDGEEPCVLSSHSGSAGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK
What is the function of this protein?
Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription (By similarity).  CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets (By similarity).  Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate.  Promotes the neddylation of CUL5 via its interaction with UBE2F.  May play a role in protecting cells from apoptosis induced by redox agents (By similarity).
What are the official names of this protein?
RING-box protein 2, Rbx2, RING finger protein 7, Sensitive to apoptosis gene protein.
What is the protein family that this protein belongs to?
Belongs to the RING-box family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: F16PA_SYNP6
Sequence: MAQSTTSETHTRDLDRDCTTLSRHVLEQLQSFSPEAQDLAALMQRIGLAAKLIARRLSHAGLVDDALGFTGEINVQGEAVKRMDVYANQVFISVFRQSGLVCRLASEEMEKPYYIPENCPIGRYTLLYDPLDGSANVDVDLNVGSIFAVRRQEFYDESHEAKDLLQPGDRQIAAGYVLYGASTLLVYSMGQGVHVFVLDPSLGEFVLAQSDIQLPNSGQIYSVNEGNFWQWPEGYRQYIREMHRREGYSGRYSGALVADFHRILMQGGVFLYPETVKNPTGKLRLLYEAAPMAFLAEQAGGKASDGQKPILLRQPQALHERCPLIIGSAADVDFVEACLAESVP
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_BACLD
Sequence: MHILVVGLDYKSAPVDIREKLTFQPDELGQAMAQLKEEKSILENIIVSTCNRTELYAVVDQLHTGRYYMKMFLANWFGLSKEDISPYLKFYENDGAVEHLFRVSCGLDSMVIGETQILGQVRTSFKLAQEEKTIGTVFNYLFKQAVTVAKRCHAETDIASNAVSVSYAAVELARKIFGDLSDKHVLILGAGKMGELAVQNLHGHGIGQVTVINRTFSKAKELAGRFSGAAKSLNELQCALMEADILISSTGASGYVVTKEMIEHVNKLRKGCPLFMVDIAVPRDLDPALSEVEGVFLYDIDDLEGIVEENLKERQAVAEEVELIIEAEIVSFKQWLNTLGVVPVISALREKALTIQAETMQSIERKLPHLSTREKKLLNKHTKSIINQLLRDPILKVKEFASEADAEEKLALFTQIFDIEEAAFPDGERQDERQPVHAFKRQNPQGLTSIASE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: ITIH3_HUMAN
Sequence: MAFAWWPCLILALLSSLAASGFPRSPFRLLGKRSLPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEMEYPENAILDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEVDMKEMEKALQERDYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLTSMVVTKPEDNEDERAIADKPGEDAEATPVSPAMSYLTSYQPPQNPYYYVDGDPHFIIQIPEKDDALCFNIDEAPGTVLRLIQDAVTGLTVNGQITGDKRGSPDSKTRKTYFGKLGIANAQMDFQVEVTTEKITLWNRAVPSTFSWLDTVTVTQDGLSMMINRKNMVVSFGDGVTFVVVLHQVWKKHPVHRDFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVSDIRPGSDPTKPDATLVVKNHQLIVTRGSQKDYRKDASIGTKVVCWFVHNNGEGLIDGVHTDYIVPNLF
What is the function of this protein?
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H3, ITI heavy chain H3, ITI-HC3, Inter-alpha-inhibitor heavy chain 3, Serum-derived hyaluronan-associated protein, SHAP.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOP_NEUCS
Sequence: MIKFYFTTFHMKFPARLFSTSFTLNNTNIINEKDVKYITKNFLLENSNGFNLIKNIINSDETSEVKQNKIEVELNNIWHTEITDILQKKRSLGLDAIGSSILAKDFHNLIGDIENFINKGRTNKLPGVEYLKPSLIISIVLGKVIPFSLRHSDIFNQPTHSLFAEIGKILKYQSIFELHHRIGLIQNRVEEIKNYTEKKLVSEFNKLTKVLDEYKNTLKNLEELSGESIIKVGLGFTALLSETSEFYSLEEQIIAKNKSIRYIIPKNKLKTLINNITLMDTIELPMIIPPLEWKIDDNEKIIEYGGTILNNKHRIRPLRTKSVENSDANDMTYNKELVDAVNFKSKIPYTINLKILDFITRDEFINRDKKDNVIIYKHIHPDSALLGEYMKDRKNPKISEITTHNSKFLYHSSIISIAKLMKDVKEFYMTVFIDWRGRFYTSSCALNIQGGELARSLLLFKEGQKLNDIGLKALKIYTANAFGLDKRSKEERLDWVEQNLHKIIDIDNYEIWREADEPLLFLACALELKGYNEDPNFISHLPILMDATCNGLQHLSAMVNDFVLAEKVNLLKSTENDNPRDLYSEVIPHIKQEILEASKSYEHTNLERINVERCLVKRGLMTITYGATERGIYDQIVSKFFQKDEWNKTVGLHFVCIDSDIAPKDVVFTQKNILLLSKIIYNSLFKIHPNLNTLMVYFNSIVKVLCELDLPVNWVTPYGLVIQQKYNKFTKYNETTYVASKRYKLVLRKADTTSISKQKQIQAFIPNFVHSMDGSNIVLLINTIRDEGRKINFASIHDCFATHANDTAWLSWYVKQSFIRIYSDSSFLRRFHNYIQLRIQAKYGEDAHFDKDGVLTHVTIDNGTDIPDRIDIPKPLVVNKDNKIYKEILHSEYFIN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
Probable DNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the phage and mitochondrial RNA polymerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TRMD_FRATW
Sequence: MKFGIISIFPEMFKAINDFGVTARAIKDSKVSISCFNPRDYTTDRHATVDDTSFGGGAGMVMKYQPLSAAIEDAKNTLGCGTKVVYLSPQGSIFNHRKAQELLQNDSLILLCGRYEGVDERLIQDYVDEEISVGDFVLSGGELPAMLVMDSLIRLLPEVLGNKESVVEDSFYDGLLDYPHYTKPAVLPNGNAVPDVLLSGNHKEIAKWRRKQKLIRTYERRKDLIECLCLSAKDKQILDDYKIDKVSTKGEE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.