PharMolix/UniProtQA huggingface dataset:
Protein: DNMT1_BOVIN
Sequence: MPARTAPARVPALASRAFSLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLRTEIKNQLCDLETKLHKEELSEEGYLAKVKSLLNKDLSLENGAHAFSREANGCLENGSQTSGEDCRVVMAEKGKPPKPVSRLYTPRRSKSDGETKSEVSSSPRITRKTTRQTTITSHFPRGPAKRKPEEEPEKVKSDDSVDEEKDQEEKRRRVTSRERVAGLLPAEEPGRVRPGTHMEEEGRDDKEEKRLRSQTKEPTPKHKAKEEPDRDVRPGGAQAEMNEGEDKDEKRHRSQPKDLASKRRPEEKEPERVKPQVSDEKDEDEKEEKRRRTTYRELTEKKMTRTKIAVVSKTNPPKCTECLQYLDDPELRYEQHPPDAVEEIQILTNERLSIFDANESGFESYEDLPQHKLTCFSVYCKRGHLCPIDTGLIEKDVELLFSGSAKPIYEDDPSPEGGINGKNFGPINEWWIAGFDGGEKALLGFSTSFAEYILMDPSPEYAPLFSVMQEKIYISKIVVEFLQSNPDSTYEDLINKIETTVPPCMLNLNRFTEDSLLRHAQFVVEQVESYDRAGDSDEQPIFLSPCMRDLIKLAGVTLGKRRAERRQTIRQPAKEKDKGPTKATTTKLVYQIFDTFFAEQIEKDDKEDKENAFKRRRCGVCEICQQPECGKCKACKDMVKFGGSGRSKQACQKRRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQGKKKKQNKNRISWVGDAVKTDGKKSYYKKVCIDSETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVQVIYKAPSENWAMEGGVDPEALMSEDDGKTYFYQLWYDQDYARFESPPKTQPTEDNKYKFCASCARLAEMRQKEIPRVVEQLQDLEGRVLYSLATKNGVQYRVGDGVYLPPEAFTFNIKLSSPVKRPRKEPVDEALYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCSKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPQCLQDFSAGGPDRFYFLEAYNAKSKSFEDPPNHARSTGNKGKGKGKGKNRTKSQTCEPSELETEIKLPKLRTLDVFSGCGGLSEGFHQAGISETLWAIEMWDPAAQAFRLNNPGSTVFTEDCNVLLKLVMAGEVTNSRGQKLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRYFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEPLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEIRNGASALEISYNGEPQSWFQRQLRGSQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTLARKLRYNYHDKKNGCSSSGALRGVCSCVEGKPCEPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKRCMLAKARESASAKIKEEAAKD
What is the function of this protein?
Methylates CpG residues.  Preferentially methylates hemimethylated DNA.  Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance.  Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication.  It is responsible for maintaining methylation patterns established in development.  DNA methylation is coordinated with methylation of histones.  Mediates transcriptional repression by direct binding to HDAC2.  In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9.  Probably forms a corepressor complex required for activated KRAS-mediated promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) or other tumor-related genes in colorectal cancer (CRC) cells.  Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs).  Associates at promoter regions of tumor suppressor genes (TSGs) leading to their gene silencing.  Promotes tumor growth.
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase 1, Dnmt1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PETN_PHAVU
Sequence: MDIVSIAWAALMVVFSFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CR063_HUMAN
Sequence: MNDSRQQSLFFITLPDLNKLCAVRIILSNKVADTEIRTIQMKMCRQLLFLHQDILTSPVSGILNQIWVVMAIPFYKARKLNAYVEKYGAKMEAPQRVIPVILQNCLSYSFMARLAPAWNRTGHLLIQGRDFLSQMGKQSAVVLNINVTETQVCLSIEACTIRLPAPELKEFEISQSIIKDFHANKHAVIERHSILSNWCYVLPSMKMGQIINIFHAIPAACPFHSYGDFQRHWDALYGYKLPGDCGKIKIYCNIYFKMLGERTFTYPLSCIRSQPMQFFPRVDSEVVLKSFLSDLKSKLPHICGFPIKMTSKPCYYTQELTKPNIQEHKVKPPNLTTKKMLRASLTQATSRKPACAQSLLPCSVAVDHKVELSVSQPTSGIFSALHLQPESVQGRKKSLSIRAPQVHSEVLMPNRGNTQVQHTNLSSQSNITPKFVPVFKNRLLQMNKNTSVLGSPKRKQHDVTQSKLFSLKTSMIQHDKLNLGPAIKNRYSSNIQMQAANNLNQENSRPLQEKNTESSENMTKFPSSRGKSTVSLNKNKQLSNSAVFVVSNNNLGVVKSAVDFQMKGKENLTGKGITQILGKSHGSLKLKRQPHIFESDGETEDPRLLQQQSENQAKEVGTSDHRLIVSKIAHRSKRKLCPESSKTSKKHHSDTVHYGQSSSSKKQILDSDKSKLKKSLIIHNA
What are the official names of this protein?
Uncharacterized protein C18orf63.
Protein: RNC_LACLS
Sequence: MLKLQEKLKNDYGLVFNDEDLLKTAFTHSSFTNEERLPKIANNERLEFLGDVALSLVISDYLYRTYPEKLEGELSKMRSSIVRTESLANFSRSCGFGEFLRLGHGEEKMGGRDRETTLENLFEAFLGALFIDQGMDEVRKFIQHVVIPHVKNDDYVKVIDYKTELQEVLQVGGETTITYNILKEEGPAHDRSFVAAVYNNGKELGRGLGKSKKVAEQKAAENAIKGQNHVS
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_FULGL
Sequence: MAPNLRKSHPLLKMINNSLIDLPTPSNISAWWNFGSLLGICLMTQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLYKETWNTGIILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFAIAGLTLIHLTFLHESGSNNPLGIVSNCDKIPFHPYFTLKDILGFTLMFLPLTSLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLSPFLHKAKQRTMTFRPLSQLLFWILVTNLFILTWVGSQPVEHPFIIIGQLASITYFTILLILFPIIGTLENKMLNF
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL331_STAA1
Sequence: MRVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNKYTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL25_GLAP5
Sequence: MSFKFEAEVRSAQGKGASRRLRHNGQVPAIIYGGKAEAVSIILDHDKVNNAQAHDAFYNEVLTIVVAGKEEQVKVQAIQRHPTKPKLVHLDFKRI
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: TIMP3_SCYTO
Sequence: MVFSTTAALSLLLALSSMQLSEVSEACTCMPNHPQEAFCNSDIVIRAKVVGKKLLKDGPFGTMRYTIKQMKMYRGFSKMQQVQYIYTEAAESLCGVRLQVNKFQYLITGRVFDGEVYTGVCNFIVPWDRLTLSQRKGLNHRYQYGCNCKIKPCYYLPCFVTAKNECFWTDMLSDQGYMGHQAKHYVCIRQKEGYCSWYRGAAPPDKTRINATDP
What is the function of this protein?
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.  May form part of a tissue-specific acute response to remodeling stimuli (By similarity).
What are the official names of this protein?
Metalloproteinase inhibitor 3, Tissue inhibitor of metalloproteinases 3, TIMP-3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RS13_SHEB9
Sequence: MARIAGINIPDQKHTVIALTAIFGIGRTRARAICAATAIAETAKIKELSEAQIDILREEVAKYIVEGDLRREISMNIKRLMDLGCYRGLRHRRSLPLRGQRTKTNARTRKGPRKPIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: KCNE1_RABIT
Sequence: MIPPNATAVMPFLTTLGEETAHLQGSSATSLARRGPLGDDGQMEALYILMVLGFFGFFTLGIMLSYIRSQKLEHSHDPFNVYIEANDWQEKDRAYFQARVLESCRGCYVLENQLAVEHPDTHLPELKPSL
What is the function of this protein?
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits.  Modulates the gating kinetics and enhances stability of the channel complex.  Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.  Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel.  The outward current reaches its steady state only after 50 seconds.  Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
What are the official names of this protein?
Potassium voltage-gated channel subfamily E member 1, Delayed rectifier potassium channel subunit IsK, IKs producing slow voltage-gated potassium channel subunit beta Mink, Minimal potassium channel.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNE family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Apical cell membrane. Membrane raft. Note=Colocalizes with KCNB1 at the plasma membrane (By similarity). Targets to the membrane raft when associated with KCNQ1 (By similarity).
Protein: GLMM_COXBN
Sequence: MQKKYFGTDGIRGKVGNSLINAEFMLKLGWAVGRVLANSHSATVLIGKDTRISGYMIESALQAGLSAAGVNIKLTGPMPTPAIAYLTNSVRADAGIVISASHNHYPDNGVKFFNKDGFKLSDELELAIEKQIDKPMKTVVADRLGKAARMNEAHGRYIEFCKSTFPSNLTLKGLKIVVDCANGAAYAVAPSIFHELGAEVVAIADDPDGFNINQTCGATDTAHLQEMVVKHNADVGIAFDGDGDRLIMVDHHGLRVDGDELLCIMAIDRFYLKENAPLGVVGTIMSNLGLEQTLKRHHIAFERSPVGDRYVLDLMQQKGWFLGGESSGHIVDLGFTTTGDGVITALQILRIMQQAEKPLADLKKVMVKNPQVLINVPIKGILDIAQNPNIKKAITEAEKQLNGAGRILLRPSGTEPVIRVMVEGSDEGIVRQTAEMLAAAVQQSTL
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SERF1_BOVIN
Sequence: MARGNQRELARQKNMKKSQEISKGKRKEDSLTTSQRKQRDSEIMQQKQKAANERKSMQTREK
What is the function of this protein?
Positive regulator of amyloid protein aggregation and proteotoxicity (By similarity).  Induces conformational changes in amyloid proteins, such as APP, HTT, and SNCA, driving them into compact formations preceding the formation of aggregates (By similarity).
What are the official names of this protein?
Small EDRK-rich factor 1.
What is the protein family that this protein belongs to?
Belongs to the SERF family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: NHAA_HAEIE
Sequence: MNFLLCIFKGVYVIKLIQRFFKLESAGGILLLFSAVVAMLLANSPLSNQYNDFLNLPVSLQIGSFSINKTLIHWINDGFMAVFFVLVGMEVKKELFEGALSTYQQAIFPAIAAIGGMVIPAVVYWFIAKQDPSLANGWAIPMATDIAFALGIMALLSKQVPLPLKIFLLALAIIDDLGAIVVIALFFSHGLSVQALIFSAVAIIALILLNRFKVSALCAYMVVGAILWASVLKSGVHATLAGVIIGFSIPLKGKKGERPLDDFEHILASWSSFVILPLFAFANAGVSFAGIDVNMISSPLLLAIASGLIIGKPVGIFGFSYISVKLGLAKLPDGINFKQIFAVAVLCGIGFTMSMFLASLAFDANAGESVNTLSRLGILFGSTVSAILGYLFLKQTTKLS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NRFH_DESVH
Sequence: MSEEKSRNGPARLKLVLGGATLGVVALATVAFGMKYTDQRPFCTSCHIMNPVGVTHKLSGHANISCNDCHAPHNLLAKLPFKAIAGARDVYMNTLGHPGDLILAGMETKEVVNANCKACHTMTNVEVASMEAKKYCTDCHRNVQHMRMKPISTREVADE
What is the function of this protein?
Electron donor subunit of the cytochrome c nitrite reductase holocomplex NrfHA.  Acquires electrons from the menaquinone pool and mediates their transfer to the catalytic subunit NrfA in an anaerobic respiratory process of nitrite (PubMed:11004582, PubMed:17139260, PubMed:18597779).  The other biological function of the NrfHA holocomplex is to detoxify nitrite (PubMed:15547266, PubMed:25534748).  This function is essential for the survival of this organism as it enables it to overcome inhibition by nitrite, which is produced by other organisms living in the same environment (Probable).
What are the official names of this protein?
Cytochrome c nitrite reductase subunit NrfH, cNiR subunit NrfH, Cytochrome c quinol dehydrogenase NrfH, Cytochrome c-type protein NrfH.
What is the protein family that this protein belongs to?
Belongs to the NapC/NirT/NrfH family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: FOXD3_HUMAN
Sequence: MTLSGGGSASDMSGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEADEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEHLREQTALMMQSFGAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSHPAAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTTASLIKSEPSARPSFSIENIIGGGPAAPGGSAVGAGVAGGTGGSGGGSTAQSFLRPPGTVQSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAAAQAKWPAQ
What is the function of this protein?
Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor.  Also acts as a transcriptional activator.  Promotes development of neural crest cells from neural tube progenitors.  Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation.  Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
What are the official names of this protein?
Forkhead box protein D3, HNF3/FH transcription factor genesis.
What are the subcellular locations of this protein?
Nucleus.
Protein: NLTPX_ORYSJ
Sequence: MMRKLAVLVLAVAMVAACGGGVVGVAGAGCNAGQLTVCTGAIAGGARPTAACCSSLRAQQGCFCQFAKDPRYGRYVNSPNARKAVSSCGIALPTCH
What is the function of this protein?
Transfer lipids across membranes.  May play a role in plant defense or in the biosynthesis of cuticle layers.
What are the official names of this protein?
Non-specific lipid-transfer protein 2, nsLTP2, 7 kDa lipid transfer protein.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family. B11E subfamily.
Protein: PAND_BORPA
Sequence: MQRIMLRAKLHRVTVTEADLHYEGSCGIDEDLLDAAGMREFERIELYNVTNGERFDTYIIKAARGSGAISLNGAAARRAQVGDLLIICTYGPMSEEQSATHKPQVVLVDDANRVKEIRKFPA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_ECOBW
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: TS11_GIAIN
Sequence: MLLAIFYFVISTLTAKCTTQTQTCEAEKCEMVGETEICTRCQTGKVPIDGKCVDATANANCKNASGDGDANQVCGKMSSVPGNTLCTTVSPDGVCSVAANEYFVPPNADATHDSVVSCSEETPIHLANNKQYIGVAGCATCSAPKAPGEDNTPKAATCTKCAAGFLHTPSEGLSSCEETCPEGYFGHTATAESKKTCKSCTGGSSEAPNVKGIGDCLKCMYNEASGNTLTCEKCSAQKKPSLDKTSCNDCTGQNCAFCSSSGGDCEGCDSGFILDGQNCVKSDCKTENCKACTNPKAANEVCTECISTHHLTPTSQCVQYCQALGNYYAGTNADNKKACKECTVANCKTCNDQGQCQTCNDGFYKNGDACSPCHESCKTCSAGTASDCTECPTGKALKYGNDGTKGTCGEGCTTGQGSGACKTCGLTIDGASYCSECDTQNEYPQNGICTSTTARTVATCKNSNVANGICSSCTNGFLRMNGGCYETTKFPGKSVCEGANADADTCKAPVPGYKVEAGKLVMCSKGCDTCSDATTCTKCGDGYTKIENSQTCTKCDSSCETCTGAATTCKVCATGYYKTALGESTCTSCENDSNGVIGVKGCLNCAPPSSSTGSVLCYLMKGENTGGSVNKSGLSTGAIAGISVAAVVVVAGLVGFLCWWFICRGKA
What are the official names of this protein?
Major surface trophozoite antigen 11.
What is the protein family that this protein belongs to?
Belongs to the Giardia variant surface protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GTR1_MOUSE
Sequence: MDPSSKKVTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWNHRYGEPIPSTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVAAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNADLWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEEGRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLERLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
What is the function of this protein?
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed:17320047).  Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (By similarity).  Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (By similarity).  In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity).
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1, GT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Photoreceptor inner segment.
Protein: TPIS_FRATH
Sequence: MQKLIMGNWKMNGNSTSIKELCSGISQVQYDTSRVAIAVFPSSVYVKEVISQLPEKVGVGLQNITFYDDGAYTGEISARMLEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTITPVVCIGESLDDRKSGKLKQVLATQLSLILENLSVEQLAKVVIAYEPVWAIGTGVVASLEQIQETHQFIRSLLAKVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEFNEIINQANKICTE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP137_ARATH
Sequence: MAAIVAIGRKLARTPQWRIVQHQSLLRRAVSTSFSSSVSQNHSFSSAFHRAGHVHSQVLSYLPHFASSNRFSTKTISETFDINLTALAPLEKGLIDLIRQVSELESEADAMASLEDSSFDLNHDSFYSLIWELRDEWRLAFLAFKWGEKRGCDDQKSCDLMIWVLGNHQKFNIAWCLIRDMFNVSKDTRKAMFLMMDRYAAANDTSQAIRTFDIMDKFKHTPYDEAFQGLLCALCRHGHIEKAEEFMLASKKLFPVDVEGFNVILNGWCNIWTDVTEAKRIWREMGNYCITPNKDSYSHMISCFSKVGNLFDSLRLYDEMKKRGLAPGIEVYNSLVYVLTREDCFDEAMKLMKKLNEEGLKPDSVTYNSMIRPLCEAGKLDVARNVLATMISENLSPTVDTFHAFLEAVNFEKTLEVLGQMKISDLGPTEETFLLILGKLFKGKQPENALKIWAEMDRFEIVANPALYLATIQGLLSCGWLEKAREIYSEMKSKGFVGNPMLQKLLEEQKVKGVRKSKRMNLQKVGSQEGYKGQRSVDRK
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g80880, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSBB_SACOF
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVSGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSISGGTVTNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLAGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQAVNPAWGAEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSDGLAENLSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRDKEGRELFVRRMPTFFETFPVVLVDEEGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHATFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGTFQKVGDPTTRRQAA
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: IRAP_ECOLI
Sequence: MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_SYNY3
Sequence: MNSPVDRILIFDTTLRDGEQSPGATLTVEEKLSIARALARLGVDIIEAGFPFASPGDFEAVQKIAQTVGTENGPVICGLARATQKDIKAAAEALKPAAKHRIHTFLATSDIHLEHKLKKTRAEVLAIVPEMVAYAKSLVNDIEFSPEDAGRSDPEFLYQVLEAAISAGATTINIPDTVGYTTPAEYGALIKGIADNVPNIDQAIISVHGHNDLGLAVANFLEAVKNGARQLECTINGIGERAGNAALEELVMALHVRRSYFNPFLGRPADSTAPLTNIDTKHIYATSRLVSELTGMMVQPNKAIVGANAFAHESGIHQDGVLKNKLTYEIMDAESIGLTNNQIVLGKLSGRNAFGTRLKELGFDLSDTELNNAFIRFKEVADKRKEITDWDLEAIVNDEIRQPPELFRLERVQVSCGEPSVPTATLTIRTPAGPEETAVAIGTGPVDAVYKAINQIVQLPNELLEYSVTSVTEGIDALGKVSVRLRHNGVIYTGYAANTDIIVASARAYLGALNRLYAALEKSREHPPVVASL
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RL21_RICTY
Sequence: MFAVIKAGGKQYKVDRNSVIKIEKIDGELGSKVQFDQILMIGEYSKPSFIGTPIVKGAIVTAEITNQLKDNKIIAFKKKRRKNYRRKAGHRQELTELKILDITKQ
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.