PharMolix/UniProtQA huggingface dataset:
Protein: ISPE_CUTAK
Sequence: MTVTVRVSAKVNLALGVGGLAPDGFHPLATVFEAICIYDEVAVTRRDDSRITLTVSGEDADQVPTDETNLAWRAVELVREEFASEWGKRGHGADIHIDKSIPVAGGMAGGSADAAGALMAAAALCRLPYSPEELQPLAAQLGSDVPFCLTGGVALGRGRGDRLAPVICRGRHRWVFATSNQGLSTPAVYRRFDELGGTPGGETVPNDLISALTRGDLDAVAASLSNDLQAAAIDLRPELEEVLTVGREVGALTALVSGSGPTCAFLVRDTAGAKKVSAAVSNLPQVHRTRTARGPAAGAQLLPGPVGSFA
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: S10A7_BOVIN
Sequence: MSSSQLEQAITDLINLFHKYSGSDDTIEKEDLLRLMKDNFPNFLGACEKRGRDYLSNIFEKQDKNKDRKIDFSEFLSLLADIATDYHNHSHGAQLCSGGNQ
What are the official names of this protein?
Protein S100-A7, Calcium-binding protein in amniotic fluid 2, CAAF2, Dander minor allergen BDA11, Dermal allergen BDA11, S100 calcium-binding protein A7.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Secreted by a non-classical secretory pathway.
Protein: SLAP2_BACAN
Sequence: MAKTNSYKKVIAGTMTAAMVAGIVSPVAAAGKSFPDVPAGHWAEGSINYLVDKGAITGKPDGTYGPTESIDRASAAVIFTKILNLPVDENAQPSFKDAKNIWSSKYIAAVEKAGVVKGDGKENFYPEGKIDRASFASMLVSAYNLKDKVNGELVTTFEDLLDHWGEEKANILINLGISVGTGGKWEPNKSVSRAEAAQFIALTDKKYGKKDNAQAYVTDVKVSEPTKLTLTGTGLDKLSADDVTLEGDKAVAIEASTDGTSAVVTLGGKVAPNKDLTVKVKNQSFVTKFVYEVKKLAVEKLTFDDDRAGQAIAFKLNDEKGNADVEYLNLANHDVKFVANNLDGSPANIFEGGEATSTTGKLAVGIKQGDYKVEVQVTKRGGLTVSNTGIITVKNLDTPASAIKNVVFALDADNDGVVNYGSKLSGKDFALNSQNLVVGEKASLNKLVATIAGEDKVVDPGSISIKSSNHGIISVVNNYITAEAAGEATLTIKVGDVTKDVKFKVTTDSRKLVSVKANPDKLQVVQNKTLPVTFVTTDQYGDPFGANTAAIKEVLPKTGVVAEGGLDVVTTDSGSIGTKTIGVTGNDVGEGTVHFQNGNGATLGSLYVNVTEGNVAFKNFELVSKVGQYGQSPDTKLDLNVSTTVEYQLSKYTSDRVYSDPENLEGYEVESKNLAVADAKIVGNKVVVTGKTPGKVDIHLTKNGATAGKATVEIVQETIAIKSVNFKPVQTENFVEKKINIGTVLELEKSNLDDIVKGINLTKETQHKVRVVKSGAEQGKLYLDRNGDAVFNAGDVKLGDVTVSQTSDSALPNFKADLYDTLTTKYTDKGTLVFKVLKDKDVITSEIGSQAVHVNVLNNPNL
What is the function of this protein?
The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of bacteria.
What are the official names of this protein?
S-layer protein EA1.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer.
Protein: YOS6_SCHPO
Sequence: MAFDKLANVATVDAIFAISSSTFLWSTWVLQRTILKRPNFFSPNPVVEKMVHPTLITWKLFSFTSVLTVSTFTFASCLIMRTIGVENIKEFGLYAREKLSFARAKPVKDDITSFPNHKISIT
What are the official names of this protein?
Uncharacterized membrane protein C21C3.06.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Multi-pass membrane protein.
Protein: ZNTB_SHIDS
Sequence: MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLHLNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPDQLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSEFIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHRSKWL
What is the function of this protein?
Zinc transporter.  Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.
What are the official names of this protein?
Zinc transport protein ZntB.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPRTL_STRA1
Sequence: MTNYVKKVSIEDFGCQFLHTAHWNNRLRTTGGRFFPNDRHLDFNPKIYREFGIDIFRKIVRHELCHYHLYIQGKGYQHRDKAFKELLEKVDGLRYTPRVTAVKVNYHHYSCQSCGQVYRRRRRVNLRKFACGYCHGRLIESF
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INP52_YEAST
Sequence: MKILLSKQQTRKIAIVSETHGLVFRPINSKNSRRSTCAVELVPKAELNGNGFRRLSNHEIYGFIGLIEIEGLMFIATITGKSKVAQPIPNKTVNKIYAVDFFCLNNSKWDFMDIDSSGYPIVTNDGDFAISSPPSISTHSSRSSLRSSSSRSLNAQEQAPKHPCHELRKLLSNGSFYYSTDFDLTCTLQKRGFTEHSLSFDDFDREFMWNSFLMDEIITYRDRLDVTAKELLDQRGFLTTVIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMYSSQYCYAFTQIRGSLPIFWEQDTSLISPKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNSEKMKIGRDVFLTSFDFHRETSQDGFAAASRIIPKIRNTILDAGYFSYDVKEGRLISEQDGVFRTNCLDCLDRTNLIQQTISLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGDQISQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLLGKLPHQQVVELYDPICEYVNERLLESEEKFTTHSNINLFVGTFNVNGNSRRADLSKWLFPIGDKFKPDVVVLGLQEVIELTAGSILNADYTKSSFWETMVTDCLNQYEEKYLLLRVEQMSSLLILFFARSDRAYNIKEVGGSTKKTGFGGITGNKGAVAIRFDYGATSFCFVNTHLSAGASNIDERRNDYNNIYRNITFPRSKTIPHHDSLFWLGDLNYRITLTNDEVRRELRAQKDGYIDRLLQYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDYGTDNYDTSEKARTPSWTDRIIYKGENLHPLAYSDAPLKISDHKPVYAAYRANVKFVDEKEKLNLVEKLYAEYKNTHPEALTTGPDELSHARMEKQKESIPLDATVQSAGIKLIDLDDTSSCVSPLLSGPSPQPSVVGPGGLSNVSPDKSKLNVLPPPPPTSRHNKEPSSKLLSPTKEISIVSVSPRKGESNLPALERHSTPKPLPPVPALSLSKPVSLQKSSSELQHAKETIDNGKIVPRPCPPIRRKSSTAPDEISTSTKNSGVSTTEDPEPAKASTKPEKPPVVKKPHYLSVAANKLNTSQEHSIKVSPSNSKSEEELPCKKKSKPKVPAKNPELEKLSVHPLKPCDPN
What is the function of this protein?
Dephosphorylates a number of phosphatidylinositols (PIs) like phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), but also phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Controls the cellular levels and subcellular distribution of phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-bisphosphate.  Specifically functions within the early endocytic pathway and actin organization.
What are the official names of this protein?
Polyphosphatidylinositol phosphatase INP52, Synaptojanin-like protein 2.
What is the protein family that this protein belongs to?
In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch.
Protein: TGT_RUEST
Sequence: MAELFNFEMTATDGKARTGVIHTPRGEIRTPAFMPVGTAATVKAMMPESVRATGADILLGNTYHLMLRPTAERIDRLGGLHKFMNWDRPILTDSGGFQVMSLAGLRKLTEKGVTFKSHIDGSRHELTPERSMEIQRLLGSDIVMCFDECPALPADRDRIAESMRLSMRWAERSREAFGDRPGHALFGIQQGGLEQDFREESAEALTKIGFDGYAVGGLAVGEGQEAMFGCLDYAPDMLPVDKPRYLMGVGKPDDIVGAVSRGIDMMDCVLPSRSGRTGQAFTRHGVVNIKNARHQDDPRPLDENCSCPACSNYSRAYLHHVFRSNEMISGMLLTWHNLHYFQDIMAGMRESIAAGTFEAWQKTFHETRAQGDIEPL
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ADA2B_RABIT
Sequence: AIAAVITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNCKRTPRRIKCIILTVWLIAAAISLPPLIYKGDQGPQPHGAPQCKLNQEAWYILSSSLGSFFVPCLIMILVYLRIYLIAKRSHRRGPRAKGGPGEGESRQACPVPGGPSASAKLPTLATPVASASEANGPSKPAGEKEEGETPEDPGTQALPPGWATLPNSGQGQKEGVSGASLEEEAEEEEEEEEEEDEPQAVPVSPASVGSPPLQQPQGSRVLATLRGQVLVGRGVGAMSGQWWRRRAQLSREKRFTFVLAVVIGVFVLCWFPFFFSYSLSAICPQQCRVPHGLF
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
What are the official names of this protein?
Alpha-2B adrenergic receptor, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor, Alpha-2BAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Interaction with RAB26, GGA1, GGA2 and GGA3 mediates transport from the Golgi to the cell membrane.
Protein: HUTU_BACC3
Sequence: MEKVQQTIRAPRGTELQTKGWVQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWESYQAIVDSLKTLESDETLLVQSGKPVAIFKSHEDAPRVLLANSNLVPKWANWDHFRELEKKGLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFGGSLKGTLTLTAGLGGMGGAQPLAVTMNGGVVIAIDVDKRSIDRRIEKRYCDMYTESLEEALAVANEYKEKKEPISIGLLGNAAEILPELVKRNITPDLVTDQTSAHDPLNGYIPVGYTLEEAAKLREEDPERYVQLSKESMTKHVEAMLAMQEKGAITFDYGNNIRQVAFDEGLKNAFDFPGFVPAFIRPLFCEGKGPFRWVALSGDPEDIYKTDEVILREFADNEHLCNWIRMARQQVEFQGLPSRICWLGYGERAKFGRIINEMVANGELSAPIVIGRDHLDCGSVASPNRETEAMKDGSDAVADWPILNALINSVNGASWVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVKTAKEKGVNIPMMK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4205_MYCGI
Sequence: MTSAAAIPTVTLNDDNTMPVIGLGVGELSDAETEQAVTAALEAGYRLIDTAAAYGNEAAVGRAIAASGVPRDELFVTTKLATEDAGFQSSQDALRASLERLGLDYVDLYLIHWPVSQQGKHVDSWGGLMKSKEVGLTRSIGVANFHGHHLDDIISLSFFTPAVNQIELHPLLNQAELRAVNAEHGIATEAYGPLGVGNLLSHSAVNAIAEAHGRTPAQVLIRWSLQLGNIVIPRSSSPERIRSNIDVFGFELSEEQMSTLNGLDDGTRFRPDPETYSGS
What are the official names of this protein?
Uncharacterized oxidoreductase Mflv_4205.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: AS1AB_XENLA
Sequence: MAKVQILNMVVLDNPCPFHNPFQFEITFECIEDLPDDLEWKIIYVGSAESEEYDQTLDSVLVGPVPAGRHMFVFQADAPNCSLIPESDAVGVTVVLITCTYRGQEFIRVGYYVNNEYSDPELRENPPLKAHFGQLQRNILASNPRVTRFHINWECTSEAKMEDIENVDPASNTMLPPNCAPSKGLAAALNTLPENSMDCM
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
What are the official names of this protein?
Histone chaperone asf1a-B, Anti-silencing function protein 1 homolog A-B.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTA_SPHGR
Sequence: PGPDVKCVCCQDGKECPCKGGECCITGSCCKEGDGLCCGKCSNAACKCADGCKCGSGCSCTLGNCTC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-A, MTA.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 4 family.
Protein: TXND9_MOUSE
Sequence: MEGNGSVDMFSEVLENQFLQAAKLVENHLDSEIQKLDQIGEDELELLKEKRLAALRKAQQQKQEWLSKGHGEYREIGSERDFFQEVKESEKVVCHFYRDTTFRCKILDRHLAILAKKHLETKFLKLNVEKAPFLCERLRIKVIPTLALLRDGKTQDYVVGFTDLGNTDDFTTETLEWRLGCSDVINYSGNLMEPPFQSQKKFGTNFTKLEKKTIRGKKYDSDSDDD
What is the function of this protein?
Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin.
What are the official names of this protein?
Thioredoxin domain-containing protein 9, ATP-binding protein associated with cell differentiation.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Co-localizes with beta-tubulin in the centrosome.
Protein: RSGA_BACAN
Sequence: MPEGKIVKALSGFYYVQHEEGITQCRGRGVFRKNKITPLVGDQVVFQADNPSEGYVLEVFDRKNELVRPPIANVDQAILVFSAVEPDFNPGLLDRFLVLIEYHNIKPIICISKMDLVDEKMRETVEAYANDYREMGYDVLFTSINTSESIDILKPFLEGCVSVVAGQSGVGKSSMLNVLRPELELKTNDISSHLGRGKHTTRHVELIAIGSGLVADTPGFSSLDFIDIEVEDLTYCFPELKEASQYCKFRGCTHLSEPKCAVKAAVEEGKITEYRYKNYKQFVEEIRERKPRY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_STRA5
Sequence: MKRKEIIDDVTMKRAITRITYEIIERNKNLDNIVLAGIKTRGVFLAKRIQERLKQLENLDIPVGELDTKPFRDDMKVEVDTTTMPVDITDKDIILIDDVLYTGRTIRAAIDNLVSLGRPSRVSLAVLIDRGHRELPIRADYVGKNIPTSQFEEILVEVMEHDGYDRVSIIDPS
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: LON_MYCPN
Sequence: MPAVKKPQILVVRNQVIFPYNGFELDVGRERSKKLIKALKNLKTKRLVLVTQKNSDQLNPEFDDIYHCGTLCDIDEIIEVPSEDGKTADYKIKGKGLQRVAITSFSDADLTKYDHHFLNSTLTENKALDKLLERIFPDKEDFAEILDSLNSFLELQELKKLSKVPKDIKRYDIITFKLASLIFKDITLQQAILEENDIEKRLQKIIGSGIEDLGHISEEARAKQRESEFDKIDNRITRKVNEQLSRQQRDFYLREKLRVIREEIGMTSKKEDEVSNIRKKLEENPYPEHIKKRILSELDHFENSSSSSQESTLTKTYIDTLMNLPWWQESKDNADVKNLIKILNKNHSGLDKVKERVVEYLAVQLRTKKLKGPIMCLVGPPGVGKSSLAKSIAEALNKCFVKVSLGGVHDESEIRGHRKTYLGSMPGRILKGMVRAKVINPLFLLDEIDKMTSSNQGYPSGALLEVLDPELNNKFSDNYVEEDYDLSKVMFVATANYIEDIPEALLDRMEVIELTSYTEQEKLQITKSHLVKRCLDDAEIKTDDLKFTDEGISYIIKFYTREAGVRQLERLIQQIVRKYIVNLQKTGEQQVVVDVDLVKKYLKKEIFDYTVRDEDALPGIVNGMAYTPTGGDLLPIEVTHVAGKGDLILTGNLKQTMRESASVALGYVKANAQSFNINPNLFKKVDINIHVPGGGIPKDGPSAGAALVTAIISSLTGKKVDPKIAMTGEITLRGKVMTIGGVKEKTISAYRGGVRTIFMPEKNERYLDEVPKDIVKDLEIILVKEYKDIYNKIFN
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERFB_YARLI
Sequence: MDFYTPPTTAGPPTRGSPESVPTTAASTFPLRKRTRAHLRARDKSDGPAPSSRGTSDRLWSWVFLKQPLSLPEHNYQAHLGNNVFLIGGRFLSARQKPLNIAVLCVILILGGLYYGFVAPWTWNHISPAIPAVFTYIFLLCVASFLRASFSDPGILPRNIHLTDRIADGSIPNEYSVEPGIDAFDPRKNTTSLSCFKQPESSENLVYLKYCSTCKIWRPPRASHCSDCDNCVDFHDHHCIWLNNCVGRKNYRYFVAFVMTGGLCGLYIVGNSIAHVICYKRHMHMTIAESLRHRPMPLVMIFLGFLGAGYPLALVGFHLWIASRGESTHEFVSMNPVTKHVVDGHVGVTLSKCKVMGSHDGFKRFSDAVLAVVCARLCAHVSPHSNPVTKQTTPQGVQKSTFRHWKRF
What is the function of this protein?
The ERF2-ERF4 complex is a palmitoyltransferase specific for Ras proteins.
What are the official names of this protein?
Palmitoyltransferase ERF2, DHHC cysteine-rich domain-containing protein ERF2, Ras protein acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MRAZ_BURO0
Sequence: MFQGASALTLDAKGRMSVPSRYREALQGQAEGRVTVTKHPDGCLLLFPRPEWEVFRAKIAALPMDAHWWRRIFLGNAMDVDLDSAGRILVSPELRMAAGLEKEVMLLGMGSHFELWDSQTYNAKEQAAMAQGMPDALKNFTF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
Protein: CDK7_DICDI
Sequence: MDKYNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQELKHDNVVNLLDIFAHKSNVYLVFELMQWDLQEVIEDKSIILKPADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLARQYGSPNKVFSPQAVTIFYRAPELLFGAKSYGPSVDIWSIGCIFAELMLRTPYLPGTGEIDQLRKICSALGTPNESNWPGVTCLPNYIKFTDHPATPFKQLFTAASDEAIDLISKMLLFNPSNRISAADALNHPYFTSGVKHTNPADLPVPFAKKASLLQQRQVLAQVQQQLLQKQQQQQQQQQQQIQSQPEPIQVDNVEQTQQAQQV
What is the function of this protein?
Catalytic part of CAK which activates cyclin-associated CDK1/CDK2/CDK4 by threonine phosphorylation, thereby allowing MPF activation.
What are the official names of this protein?
Cyclin-dependent kinase 7, CDK-activating kinase, CAK, Cell division protein kinase 7, MO15 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS81_CARHZ
Sequence: MNKPRYFKEAFAQLKPYEPHLVSYEIKLDANENPYLFPKSLLEEIFSKIGTRDFPLYPDPLAGRLRIRLSEKLGVLPENIVLGNGSDELILCLYLAFGGYGRIALSFSPSFVMYRHHAFVTQTEFFEVSYRDDFSLDLDETKKAIEKYQPHLVFLANPNNPTGTLVDIETIKKLLAYDHLLVVDEAYVEFSGVSAIDLLKKYQNLVILRTFSKARALAGLRLGYLVASVDVVKEIIKVKNPYNVNVFSQIAGEVVLANEEVFQGEIKEIVAERERLYNQLASLGLKPVKSHANFILVEFGEKAKKIHQELINHGILVRYLGGALANYLRITVGTPEENRQLLKKLGEIL
What are the official names of this protein?
Histidinol-phosphate aminotransferase 1, Imidazole acetol-phosphate transaminase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: FZR1_MOUSE
Sequence: MDQDYERRLLRQIIIQNENTVPCVSEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEHKGLFTYSLSSKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR
What is the function of this protein?
Substrate-specific adapter for the anaphase promoting complex/cyclosome (APC/C) E3 ubiquitin-protein ligase complex.  Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase.  The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely.  At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C.  Following DNA damage, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, preventing entry into mitosis.  Acts as an adapter for APC/C to target the DNA-end resection factor RBBP8/CtIP for ubiquitination and subsequent proteasomal degradation.  Through the regulation of RBBP8/CtIP protein turnover, may play a role in DNA damage response, favoring DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR).
What are the official names of this protein?
Fizzy-related protein homolog, Fzr, Cdh1/Hct1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CDC20/Fizzy family.
Protein: CCD92_HUMAN
Sequence: MTSPHFSSYDEGPLDVSMAATNLENQLHSAQKNLLFLQREHASTLKGLHSEIRRLQQHCTDLTYELTVKSSEQTGDGTSKSSELKKRCEELEAQLKVKENENAELLKELEQKNAMITVLENTIKEREKKYLEELKAKSHKLTLLSSELEQRASTIAYLTSQLHAAKKKLMSSSGTSDASPSGSPVLASYKPAPPKDKLPETPRRRMKKSLSAPLHPEFEEVYRFGAESRKLLLREPVDAMPDPTPFLLARESAEVHLIKERPLVIPPIASDRSGEQHSPAREKPHKAHVGVAHRIHHATPPQAQPEVKTLAVDQVNGGKVVRKHSGTDRTV
What is the function of this protein?
Interferon-stimulated protein that plays a role in innate immunity.  Strongly inhibits ebolavirus transcription and replication.  Forms a complex with viral RNA-bound nucleocapsid NP and thereby prevents the transport of NP to the cell surface.
What are the official names of this protein?
Coiled-coil domain-containing protein 92, Limkain beta-2.
Protein: TAL_PSEU2
Sequence: MTSKLDQLKKFTTVVADTGDFGAIKSLEPEDATTNPSLLLKAASDANNAKMLGEAFDGSKGDIGLACDRFAVAIGQEILKVVPGRVSTEVDARLSFDTNALIERSERLIGLYDAAGIKRDRVLIKLAATWEGIRAAEKLEKDGIQTNLTLLFSFAQAVACAEAGVFLISPFVGRIYDWYKKSTGTDYTGAEDPGVQSVTRIYNYYKANDFKTVVMGASFRNLNQIEQLAGCDRLTISTDLLKKLAEDTGTLERKLTPDKAGEKRSDTVKNLTESQFRWASNEDAMATEKLAEGIRQFARDQEKLEALLSAKKA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETH1_THECS
Sequence: MANPYERGPNPTDALLEASSGPFSVSEENVSRLSASGFGGGTIYYPRENNTYGAVAISPGYTGTEASIAWLGERIASHGFVVITIDTITTLDQPDSRAEQLNAALNHMINRASSTVRSRIDSSRLAVMGHSMGGGGTLRLASQRPDLKAAIPLTPWHLNKNWSSVTVPTLIIGADLDTIAPVATHAKPFYNSLPSSISKAYLELDGATHFAPNIPNKIIGKYSVAWLKRFVDNDTRYTQFLCPGPRDGLFGEVEEYRSTCPF
What is the function of this protein?
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle (Ref. 1).  Shows esterase activity towards p-nitrophenol-linked aliphatic esters (pNP-aliphatic esters) (Ref. 1, PubMed:23718548, PubMed:23592055).  Capable of degrading the plastic poly(ethylene terephthalate) (PET), the most abundant polyester plastic in the world (Ref. 1, PubMed:23718548, PubMed:23592055).  Capable of degrading the bioplastic poly(lactic acid) (PLLA) (PubMed:28671263).
What are the official names of this protein?
Cutinase 1, Poly(ethylene terephthalate) hydrolase, PET hydrolase, PETase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Secreted. Periplasm.
Protein: CAPSD_TMVKO
Sequence: MSYSITTPSQFVFLSSAWADPIELINLCTNALGNQFQTQQARTVVQRQFSEVWKPSPQVTVRFPDSDFKVYRYNAVLDPLVTALLGAFDTRNRIIEVENQANPTTAETLDATRRVDDATVAIRSAINNLVVELIRGTGSYNRSSFESSSGLVWTSGPAT
What is the function of this protein?
Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: BAMB_SHIDS
Sequence: MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPATAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamB.
What is the protein family that this protein belongs to?
Belongs to the BamB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.