PharMolix/UniProtQA huggingface dataset:
Protein: TIG_RENSM
Sequence: MKSAVENLSPTRVKLDVEVPFEELQPSIAEAYKTIAEQVQIPGFRKGKFPNRLIDQRVGRGYVLETAINEGLNGWYQNAVAETGLRPLSRPEVEITEVPDPAATDGELKFKVEVDVRPEVELPDYAGITVEVAPAEQSDEDRQKALDDLRGRFGTLKPADRPAAKDDFITIDINAKIADEDVDSATGLSYQVGAGTMLEGLDEAVEGLSTDEEAIFDTKLVGGEHAGEAAQVTVKLTAVKVRELPEADDDFAQLASEFDTIAELREDLVKQVNQSKTVEQGVEARDKVMEKLVELIEVPIPESVIEEQLEQHFDPANAHGEEDHDTEEHRVEVRENTERAFKNEIILDAVADKEEISVSQAELIDYIVNSASQYGMDPNQFAQMLDQSGQVPMVVSEVRRRKALAHVLGLATVTDTEGAAVDLSDFVKPAVDPELEAALNEAAGVTGEDDDTEAEEERVTVSADDPGAARF
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ISPG2_STRAW
Sequence: MTAISLGVPEVPVRPIAERRVSRQIQVGPLAVGGTAPVSVQSMTTTRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALAVIARKSQIPVVADIHFQPKYVFAAIEAGCAAVRVNPGNIKQFDDKVKEIARAAKEHGTPIRIGVNAGSLDRRLLEKYGKATPEALVESALWEASLFEEHDFRDIKISVKHNDPVVMVNAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPVEEIKVGIQILESLGLRQRRLEIVSCPSCGRAQVDVYKLAEEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESKIVETLIEEAMKIAEQMEQNGVASGEPAVTVS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) 2, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: NSP1_ROTHU
Sequence: MATFKDACYHYKRINKLNQTVLKLGVNDTWRPSPPTKYKGWCLDCCQHTDLTYCRGCTIYHVCQWCSQYGRCFLDDEPHLLRMRTFKNEVTKDNLKNLIDMYNTLFPITQKIIHRFINNTRQHKCRNECMTQWYNHLLMPITLQSLSIELDGDVYYIFGYYDSMNNINQTPFSFTNLVDIYDKLLLDDVNFVRMSFLPTSLQREYALRYFSKSRFISEQRKCVNDSHFSINVLENLYNPNFKVQITRNCSELSVDWNEACKLVKNVSAYFDILKTSHVEFYSVSTRCRIFTRCKLEMASKLIKPNYVTSNHKTLATEVRNCKWCSINNSYTVWNDFRIKKIYNNIFSFLRALVKSNVNIGHCSSQEKIYEYVENVLNVCDDKRWKTSIMEIFNCLEPVELNDVKYVLFNYEINWDVINVLIHSIGKVPQILTLENVITIIQSIVYEWFDITYMRNTPMVTFTIDKLRRLHIGLKTVDSDSGISDVE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.  Recognizes the host NF-kappa-B regulator BTRC through the presence of a DSGXS motif in the C-terminal substrate recognition domain.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: IPI1_KLULA
Sequence: MAKKTVRQQDFMKRKLKVGKPKQKPSNVTDTSFQMKRISLPSQTKISSGSNGKSAGNGTGVLDLNQEVIKRVSLLRHHSDVTRKETVLYFESMISRIIHLPSMNNLMQSSIPLMCDSSKQVRDELANLLDTIGKHDANVLKLQIRAITLYLNNAMTHIIAPIQRDSGMFVQVVLKYCADELVRHAWIKMLKGFFQVLGWTIVTQGNNKAKGKSISMGITSSSVLSMNKNKKHKNENLKAMLQFIRAGVLGAAAIGHEDRNPEQGNGANSVSPLLQQRYVPYMIPEFPQPYAYLKLFTRQFAKGELTSTGAETSSTDSGNMTLEELETLSCEDTHTRRMVFNQHFYPSIQRQLPALIKDGGECGRTAHSFSSTLEEILQITV
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein IPI1.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LDH1_BIFL2
Sequence: MVTMNRNKVVIVGTGQVGATAAFGIVTHGLCNELVLIDCSAAKALGEARDLDDGSEFQDRHVKVRAGDYADCKDADIVVITVGRKPPANSNRMAELGFTVGLVGEVVDNVMASGFDGVIVMVSNPVDVMAWYAWKRSGLPRTQVLGTGTALDTSRLKTIIGEETGLDPRNVGGFVMGEHGDSQFTAWSTVSLGGKPFARFLADNQDRFASVSTTEIEEKTRTRGNEIVAAKGGTNFGIASTVAGIVQTILWDERRIVPVSTLLDGEYGEHDVFLGVPTELRANGANEIVELDLSEDERAKLHHSAELVREHCEGLL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_CORGL
Sequence: MADISTTQVWQDLTDHYSNFQATTLRELFKEENRAEKYTFSAAGLHVDLSKNLLDDATLTKLLALTEESGLRERIDAMFAGEHLNNTEDRAVLHTALRLPAEADLSVDGQDVAADVHEVLGRMRDFATALRSGNWLGHTGHTIKKIVNIGIGGSDLGPAMATKALRAYATAGISAEFVSNVDPADLVSVLEDLDAESTLFVIASKTFTTQETLSNARAARAWLVEKLGEEAVAKHFVAVSTNAEKVAEFGIDTDNMFGFWDWVGGRYSVDSAVGLSLMAVIGPRDFMRFLGGFHAMDEHFRTTKFEENVPILMALLGVWYSDFYGAETHAVLPYSEDLSRFAAYLQQLTMESNGKSVHRDGSPVSTGTGEIYWGEPGTNGQHAFFQLIHQGTRLVPADFIGFARPKQDLPAGERTMHDLLMSNFFAQTKVLAFGKNAEEIAAEGVAPELVNHKVMPGNRPTTTILAEELTPSILGALIALYEHIVMVQGVIWDINSFDQWGVELGKQQANDLAPAVSGEEDVDSGDSSTDSLIKWYRANR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_SHESH
Sequence: MAIINMSELDLQGKRVLIREDLNVPVSDGVVTSDARLRAALPTIKLALEKGAAVMVMSHLGRPTEGEFNAEFSLQPVVNYLTKALECPVRLANDYLDGVEANVGELVVFENVRFNVGEKKNDEALAKKLAALCDVYVMDAFGTAHRAQASTHGVGLHAPVACAGPLLAGELEALGKAMDNPARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGHEVGKSLYEANLIEEAKRLVANAQSRGGDIPVPTDVVVAGEFSPTASATLKDVSEVTSDDMIFDIGPDSAEALSEILKNAGTIVWNGPVGVFEFDQFGEGTKRIAQAIAESDAFSIAGGGDTLAAVDKYDIADKVSYISTGGGAFLEFLEGKELPAVAMLESRGE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEAH_ECO81
Sequence: MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGVPANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKILPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: DNLI_METJA
Sequence: MLWRDVCEIFNKIEKTTKRLEKRDYFIKLIDMVKEKGKPEDLKKICYMAIGRVYPEYDERELGIGEKLLINAVTSIGIKKDELLEKIKETGDIGLAIEQLKSKIKQASLFFQPLTVDEVYETLKRVGEIEGEGSQKKKLRLISSLFLRASPIECRYLARLILEDMRIGMNVPTILDALSVYFNVPKEKLEKIYAITNDIGLLAEKLLMGDLESEELKLKLFRPIKPMLAQLTPSIEEALLEMGRAQFETKYDGARVQIHKDGNKVKIYSRRLEDVTNALPEIVEAVKNINVDKLIVEGECVAIDKQTGKPRPFQDILRRFRRKYDIGKMMKEINLRVYLFDILYKDGVSFIDEEFEKRRKVLEEIVGYENDWRTERKRIEKELKSDKIIDISYKLVTNDAKEAREFYNWSLSIGHEGVMIKNLKAPYTPGSRVRTMYKFKPTLESLDVVITKAKRGMGKRKDWYGSFEICVRDEEGNLYPIGHVGTGLTEADLEFLKEEIDKIIIRDLGEEVEVEPKIVIEVAYEEIQKSDKYPCGYALRFPRVVRFRFDKGVNEINTIEDVERIYEIQRGRK
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: RK3_NEOYE
Sequence: MSVGILGTKVGMTQFFDEAGLSIPVTVIQVGPCVITQIKAVSTDGYNAIQVGYKQVAEQKLNKPLLGHLKKSQAPPLKYLREYEMKSTDDFEVSQILSTDLFQVGQKINVSSRSVGKGFSGYQKRHHFSRGPMSHGSKNHRQPGSIGAGTTPGRVYPGKNMAGQLGNKKVTIKNLQIVSINSENDLLIVKGAVPGKPGALVKISK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TSAD_YERPB
Sequence: MRVLGIETSCDETGIAVYDDKAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEANLSAKDIDAVAYTAGPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPMLEENAPEFPFVALLVSGGHTQLISVTGIGEYLLLGESVDDAAGEAFDKTAKLLGLDYPGGPMLSRMAQQGTVGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRANGDDDQTRADIARAFEDAVVDTLAIKSKRALDQTGFKRLVIAGGVSANQTLRLKLADMMQKRGGEVFYARPEFCTDNGAMIAYAGMVRLRSNLNSELSVSVRPRWPLSELPKV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTL1_SALTY
Sequence: MKPAPGAEPVRMYKSPYGGKYGVWRLADCVPMRAKRPQTEKQRLASTRLGLQARMKSERGRFAMLAHTWLALGPVFLDTETTGLDAGAQALEIGLVNARGERIFETRLKPTVGIDPAAAAVQIVTEPYRFPVLSVRLA
What are the official names of this protein?
Uncharacterized protein pSLT049.
What is the protein family that this protein belongs to?
To phage 186 CP81.
Protein: DCD_XYLFM
Sequence: MSIKSDRWIRHMAKQHGMIAPFEPGQIKQNTTGQRIVSYGTSSYGYDVRCSREFKIFTNINSTIVDPKQFDNGSFIDVESDVCIIPPNSFALARTIEYFRIPRNVLVICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPARIYANEGVAQMLFLQADPDDVCETSYRDRNGKYQGQTGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: HRCA_BACC1
Sequence: MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLAPQNLPNDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKILDGTFQVPLSEKIYFGGKANMLSQPEFHDIQKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSSTAMEDCSLISATYSIGEEQVGTIAILGPTRMQYSRVISLLQLFTRQITDGLKK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: ATG19_YEAST
Sequence: MNNSKTNQQMNTSMGYPLTVYDECNKFQLIVPTLDANIMLWCIGQLSLLNDSNGCKHLFWQPNDKSNVRILLNNYDYGHLFKYLQCQRKCSVYIGEGTLKKYNLTISTSFDNFLDLTPSEEKESLCREDAHEDPVSPKAGSEEEISPNSTSNVVVSRECLDNFMKQLLKLEESLNKLELEQKVTNKEPNHRISGTIDIPEDRSELVNFFTELKTVKQLEDVFQRYHDYERLSQECDSKTEIASDHSKKETKIEVEPPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFTDAGDKPTTQIIDMGPHEIGIKEYKEYRYFPYALDLEAGSTIEIENQYGEVIFLGKYGSSPMINLRPPSRLSAESLQASQEPFYSFQIDTLPELDDSSIISTSISLSYDGDDNEKALTWEEL
What is the function of this protein?
Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy.  Recognizes cargo proteins, such as APE4, LAP3, LAP4 and AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole.  Involved in the organization of the preautophagosomal structure (PAS).  ATG19 association with cargo protein is required to localize ATG11 to the PAS.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates, and is essential for the survival of cells subjected to severe ER stress.  Also plays a role in regulation of filamentous growth.
What are the official names of this protein?
Autophagy-related protein 19, Cytoplasm-to-vacuole targeting protein 19.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Note=Also found in other perivacuolar punctate structures.
Protein: RAD9B_MOUSE
Sequence: MLKCGMTGGQVKVFGKAVQTLSRVSDELWLDPSEKGLALRSVNSCHSTYGYVLFSSMFFQHYQWSPFATMSDTDLPLNLNCKLAIKSVLPIFRCLNYLERSVEKCTVVARADKCRVVIQFFGKHGIKRTHNVYFQDSQPLKIIFEKSLCANILMIKPRLLTEAIALLTSNQEEVTFSVTPGNFCLKSLSGELLDLTSSVYSEMSFGPEEFDFFQVGLDTEITFCFKELKGILTFSEVMHAPLAIYFDFPGKPVVLSVEDMLLEANFILATLVDYPSRTSSPQLLPLSQARRSHPIQSSAPEDKSRVSQTPESISRAAPKRLFPKDSPDSSSAAETKRASAGQDDIFEVPESVVSDMEEERSPSHLRKFSCMFFGAVSCEQQEYAGHPLDSLAVASDSEEDVSG
What are the official names of this protein?
Cell cycle checkpoint control protein RAD9B, DNA repair exonuclease rad9 homolog B, mRAD9B.
What is the protein family that this protein belongs to?
Belongs to the rad9 family.
Protein: ASPG_LUPAR
Sequence: PPERRKPREEGLRHCLQIGVEALKARKSPLDVVELVVRELENNEHFNAGIGSVLTNSGTVEMEASIMDGKSMKCGAVSGLSTVLNPISLARLVMEKTPHMYLAFQGAQDFAKQQGVETVDSSHFITAENVERLKLAIEANRVQIDYSQYNYTQPVQDDAEKELPVANGDSQIGTVGCVAVDSQGNLASATSTGGLVNKMVGRIGDTPLIGAGTYANELCAVSATGKGEAIIQATVARDVAALMEFKGLSLKEAADYVVHERTPKGTVGLIAVSAAGEIAMPFNTTGMFRACATEDGNSEIAIWPPA
What is the function of this protein?
Degrades proteins damaged by L-isoaspartyl residue formation (also known as beta-Asp residues).  Also has L-asparaginase activity, which is used to liberate stored nitrogen during seed development.
What are the official names of this protein?
Isoaspartyl peptidase/L-asparaginase, L-asparagine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
Protein: REM20_ARATH
Sequence: MADDSELYPRFFKVFLVESASESLMIPLPFMAFLADPLPKTVKLQGLGGKLWTVSLKKISGAAYLTRGWPKFAEEHELKNGEFMTFVYDGHRTFEVSVFDRWGSKEVRAEIQAIPLSDSDSDSVVEDEKDSTDVVEDDDDEDEDEDEDDDGSFDEDEEISQSLYPIDEETATDAAVFEGNLDVEALTNPHFPTTLKNRIYELLIPANVVKDNNLEFGSSIKYIDGEGTLVGLRGKWADKRVCFKGWDRICRRNRLKKHQDTVECELLHDDQKMVHSIRVHVLRRDA
What are the official names of this protein?
B3 domain-containing protein REM20, Protein REPRODUCTIVE MERISTEM 20.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCOS_ECOLX
Sequence: MRFKISLTTRLSLIFSAVMLTVWWLSSFILISTLNDYFDNQDRDFLTGKLQLTEEFLKTETFRNKTDIKSLSEKINDAMVGHNGLFISIKNMENEKIVELYAKNSVVPAVLLNKSGDILDYMIQTEENNTVYRSISRRVAVTPEQGKSKHVIITVATDTGYHTLLMDKLSTWLFWFNIGLVFISVFLGWLTTRIGLKPLREMTSLASSMTVHSLDQRLNPDLAPPEISETMQEFNNMFDRLEGAFRKLSDFSSDIAHELRTPVSNLMMQTQFALAKERDVSHYREILFANLEELKRLSRMTSDMLFLARSEHGLLRLDKHDVDLAAELNELRELFEPLADETGKTITVEGEGVVAGDSDMLRRAFSNLLSNAIKYSPDNTCTAIHLERDSDCVNVMITNTMSGQVPANLERLFDRFYRADSSRFYNTEGAGLGLSITRSIIHAHGGELSAEQQGREIVFKVRLLMD
What is the function of this protein?
Probable member of a two-component regulatory system PcoS/PcoR.  May activate PcoR by phosphorylation.
What are the official names of this protein?
Probable sensor protein PcoS.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRP5_SCLS1
Sequence: MADAIEIEEMMLEDRDIAVVLEVPTRRRRSRERDYRDRRDDSYDDRARRRREDSTDSWSRSRGDENRGQTPRSDSGAKVHDAPKASAPAAQTEEQKKAERLAKLEAWKKKMAEDKERKEKELAAGGTRKLLDDIDQKANGSSSQPSPNTPTTPSTSAISGDLAPTNYAGKFDPKAIAKKAVASSSSAHALGRDLPLKELSKTSATLTSTVKGLQADKKPTAFNSTSKVSALPKTRGNLSVFGLGAKVTDNEKTYQKRALDFDEDEGSRKKLEKLPTLPMANSKEDDAALANGIEGQDDDDDAELEAAGTEEEAAAAARAAAEKREERLQEAESQPHTNGDVHMEDAPQADSTAMDEDEEIDPLDAFMEEMGDPFSLPKSNTTFVKNNTKSQPQEPEALFGDDDVDLKALDADPDEILAIANKARKKKDIPTINYANLNLPPFRKNFYTEPAELVDMTEAEINDLRLELDGIKVAGKDVPKPVQKWSQCGLDVKSLDVIKKLGYDKPTSIQMQAIPAIMSGRDVIGVAKTGSGKTIAFLLPMFRHIRDQRPLKNSDGPIGLIMTPTRELATQIHKECKPFLKAMGLRAVCAYGGAIIKDQIADLKRGAEIIVCTPGRMIELLAANSGRVTNLQRVTYVVLDEADRMFDMGFEPQVMKVFNNIRPNRQTILFSATMPRIMDALAKKTLQSPVEIVVGGRSVVAPEITQIVEVREEKEKFHRLLELLGELYNADEDARTLIFVDRQEKADDLLKDLMRKGYPCMSIHGGKDQVDRDSTIDDFKAGVVPIMIATSVAARGLDVKQLKLVVNFDAPNHLEDYVHRAGRTGRAGNTGTAVTFITEEQEQYSVGIAKALEQSGQEVPERLNEMRKSYKDKVKSGAKKESSGFGGKGLERFDAEREATKARERKIHKLNGDDDEEEKEEKDDDVLLKAASVVQPASASTAPPKLLGVPKGIDLDGDIKVHRTETAASSSGSKNPLDKVTSAIDAINARLNKTGQLRSGVPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYPAGKEVQAGGDPKLYILVEGDTEVVVTNAMRELMRLLKEGTMAAADAEGRAPASGRYTVT
What is the function of this protein?
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing.  Catalyzes an ATP-dependent conformational change of U2 snRNP.  Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase prp5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_ALKMQ
Sequence: MAELVAKRYAKALFQVAFEMNRYEDVTEELAFVAENLKQHSDLNELLKSPVITLGEKKEILSTIFKEQISPEVFNFLRILLDKSRQGDFQEIYEEYKILADAGKNKIEAVAITALPMDNNDLLKLQVNLSMSSGKNVKLKNEIDPTVIGGVLVKMGDKIIDGTVKARLNQMQDQLLQIIV
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LRGA_BACAA
Sequence: MSTKKVYSFLSQAFIFSAIMLISNIIATHLPIPMPSSVIGLVILFSLLCLKVIKLEQVESLGTALTGIIGFLFVPSGISVINSLGVMGQYFVQILTVIVVATVILLAVTGLFAQFILGKDEKETEDTKELKVVNKGRKHGKVA
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOXE1_HUMAN
Sequence: MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAAAAIFPGAVPAARPPYPGAVYAGYAPPSLAAPPPVYYPAASPGPCRVFGLVPERPLSPELGPAPSGPGGSCAFASAGAPATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGSSGGVETTVDFYGRTSPGQFGALGACYNPGGQLGGASAGAYHARHAAAYPGGIDRFVSAM
What is the function of this protein?
Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription.  Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor.  Also implicated in thyroid gland morphogenesis.  May indirectly play a role in cell growth and migration through the regulation of WNT5A expression.
What are the official names of this protein?
Forkhead box protein E1, Forkhead box protein E2, Forkhead-related protein FKHL15, HFKH4, HNF-3/fork head-like protein 5, HFKL5, Thyroid transcription factor 2, TTF-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: C7D55_HYOMU
Sequence: MQFFSLVSIFLFLSFLFLLRKWKNSNSQSKKLPPGPWKLPLLGSMLHMVGGLPHHVLRDLAKKYGPLMHLQLGEVSAVVVTSPDMAKEVLKTHDIAFASRPKLLAPEIVCYNRSDIAFCPYGDYWRQMRKICVLEVLSAKNVRSFSSIRRDEVLRLVNFVRSSTSEPVNFTERLFLFTSSMTCRSAFGKVFKEQETFIQLIKEVIGLAGGFDVADIFPSLKFLHVLTGMEGKIMKAHHKVDAIVEDVINEHKKNLAMGKTNGALGGEDLIDVLLRLMNDGGLQFPITNDNIKAIIFDMFAAGTETSSSTLVWAMVQMMRNPTILAKAQAEVREAFKGKETFDENDVEELKYLKLVIKETLRLHPPVPLLVPRECREETEINGYTIPVKTKVMVNVWALGRDPKYWDDADNFKPERFEQCSVDFIGNNFEYLPFGGGRRICPGISFGLANVYLPLAQLLYHFDWKLPTGMEPKDLDLTELVGVTAARKSDLMLVATPYQPSRE
What is the function of this protein?
Involved in the biosynthesis of solavetivone, a potent antifungal phytoalexin.  Catalyzes the successive and independent hydroxylations of premnaspirodiene and solavetivol.  The first hydroxylation step is 3-fold more efficient than the second hydroxylation reaction.
What are the official names of this protein?
Premnaspirodiene oxygenase, HPO, Cytochrome P450 71D55.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KITH_DICT6
Sequence: MEILNGPSGWIEVICGGMYSGKSEELIRRVRRAQIAKQKVQVFKHSLDIRYDKDYVASHTGLKIEAIPVSSSADIERLVEDDTQVVAIEEGQFFDMGIVKVCQRLADKGKRVIVAGLDQDFRGEPFGPMPYLMAVAEYVDKLHAICMKCGNVASRTQRIIDGKPAYYDDPIILVGAFETYEARCRNCHIVLRRDENEK
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSA8_TRYBB
Sequence: DQKGKSPESECNKISEEPKCNEDKICSWHKEVKAGEKHCKFNSTKAKEKGVAVTQTQTAGGTEATTDKCKGKLEDTCKKESNCKWEGETCKDSSILVNKQLALSVVSAAFAALLF
What is the function of this protein?
VSG forms a coat on the surface of the parasite.  The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
What are the official names of this protein?
Variant surface glycoprotein ANTAT 1.8, VSG.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A soluble form is released from ruptured cells by the action of a PI-PLC.
Protein: EX7S_VIBCM
Sequence: MASKKPENMSFESTIEELEQLVEQLESGDLALDEALRKFERGISLARAGQLKLDDAEQRVRILLSNSDDAPLSDFSDVAE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEXI1_DANRE
Sequence: MELIKEETAPEDDSRGRQRDCRTSVVSSKQVQRNQLEICPGLVSGDVHPMCRDRSDPEPRTGDAASDDGFPADKTSSKRDSECAAVNTDGVSDGRQGKKKHRRRPSKKKRRWKPYFKLTWEEKKELDERETARASRVRAEMFAKGLPVAPYNTTQFLMEEHDREEPDLNTELGGRKSGAIRSEDTASEDENFEAEEDDEEEGGGGSDGMGRPGQAGGEFLQKDFSETYEKYHVEALQNMSKQELVREYLELEKCMSRLEEENNWLRHVRRNPESPADGTGSQRVRELEVEVEKLRAENNELLLKTPASNEPGLNQSQPS
What is the function of this protein?
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor.  Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.  Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.
What are the official names of this protein?
Protein HEXIM1.
What is the protein family that this protein belongs to?
Belongs to the HEXIM family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Binds alpha-importin and is mostly nuclear.