PharMolix/UniProtQA huggingface dataset:
Protein: BIRC3_CANLF
Sequence: MNIVQNSIFLSNLLRSSPVFELKYDHSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGAKDRVRCFCCGLMLDNWKAGDSPTGKHRNLYPSCSFIQNLSAVSTVGAASQPPAPLSEARSTHAQSPGLERSSYFSASYSSFPVDPVDFRPSPAMSPWRAGPSCVTMKSEEDRLCTFQGWPLAFPLPSALARAGFYYVGPGDRVACFACGGKLSNWEPDDDALSEHLRHFPDCPFVEGQLQATVRYTASNLSMQTLAARSRTFCNWPPRAPVHPEQLASAGFYYMGHSDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEYLIRIKGQEFISQIQASYPHLLEQLLSTSDNTEDENTESPIVHFGPGEYHSEDAVMMNTPVVMAALEMGFSRSLVRQTVQSKILSTGENYRTVNEIVSDLLHVEDEIREEEKERAAENRESDDVSLIRKNKMVLFQHLTYVLPILDSLLMAGVLNEQEHSSIKQKARTSLQARELIDTVLVKGSSAVTIFKNSLQEIDPMLYKRFFVQQDRKYIPTEDISDLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCRDCAPSLRKCPICRGTVRGTVRTFLS
What is the function of this protein?
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis.  Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling.  The target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, IKBKE, TRAF1, and BCL10.  Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs).  Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner.  Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8.
What are the official names of this protein?
Baculoviral IAP repeat-containing protein 3, RING-type E3 ubiquitin transferase BIRC3.
What is the protein family that this protein belongs to?
Belongs to the IAP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PDAD_HALS3
Sequence: MPRIRIAWGSGVAPTEMAAYDAALADANVHNYNLIRVSSVIPADATVSPVDTAPDLGPAGNTLTVVEARGQTAGPGQASAGLAWAPRDGAPGLFYEAADETTPDDVADRVTTGITAGMDVRDWDGVEPSVRTETVTADAGEHAAAVVIAAYGDSDPVFDQ
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase, PvlArgDC.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: RPOC_BRUA4
Sequence: MNQEVMNLFNPQAPAQTFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTSLKEHQLLSEEEYMIAVDEFGEDQFTALIGAEAIYELLASMELEKIAADLRVDLAETTSDLKQKKLMKRLKIVENFLESGNRPEWMIMKIVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVADKEPGEGMMFADMGELQHALENKVVTLHTKIKGRFKTVDAEGKPVSKIYDTTPGRMITGELLPKNVNVPFDICNQEMTKKNISKMIDHVYRHCGQKETVIFCDRIMQLGFAHACRAGISFGKDDMVIPDTKAKIVADTEALTTEYEQQYNDGLITQGEKYNKVVDAWGKATDKITEEMMARLKAVEFDPVTGRQKQMNSVYMMSHSGARGSVNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDAIISEVDCGAEIGLTMQPIVDAGQIVASIGQRVLGRTALDPILHPTTGEVIVEAGRMIEEKDVEIIEKAAIQSIRIRSALTCETRNGVCAKCYGRDLARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSYLEASYEGTVKLRNRNVVRNSDGNLVVMGRNMAVLILDNTGKERAVHRVTYGSRLFVDEADTVKRGQRIAEWDPYTRPIMTEVEGYVEFEDLVDGLSVSESADESTGITKRVVIDWRSTPRGSDLKPAMVIKDKAGKILKLSKGGDARFMLSVESILSVEPGAHVKAGDVIARLPMESAKTKDITGGLPRVAELFEARRPKDHAVIAEIDGTVRFGRDYKNKRRIIIEPNDDTIEPVEYLIPKGKPFHLQDGDVIEKGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITESGDTGYIPGDHVDRIELEEINERLIEEGKKPGSGNPVLLGITKASLQTPSFISAASFQETTRVLTEAAVAGKMDTLQGLKENVIVGRLIPAGTGGMTNQIRRIATARDELIIDERRKSSGSTEANAMLVDMTNNAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: HBEGF_MOUSE
Sequence: MKLLPSVMLKLFLAAVLSALVTGESLERLRRGLAAATSNPDPPTGSTNQLLPTGGDRAQGVQDLEGTDLNLFKVAFSSKPQGLATPSKERNGKKKKKGKGLGKKRDPCLRKYKDYCIHGECRYLQEFRTPSCKCLPGYHGHRCHGLTLPVENPLYTYDHTTVLAVVAVVLSSVCLLVIVGLLMFRYHRRGGYDLESEEKVKLGVASSH
What is the function of this protein?
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4.  Required for normal cardiac valve formation and normal heart function.  Promotes smooth muscle cell proliferation.  May be involved in macrophage-mediated cellular proliferation.  It is mitogenic for fibroblasts, but not endothelial cells.  It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF.  Also acts as a diphtheria toxin receptor.
What are the official names of this protein?
Proheparin-binding EGF-like growth factor.
What are the subcellular locations of this protein?
[Heparin-binding EGF-like growth factor]: Secreted, extracellular space. Note=Mature HB-EGF is released into the extracellular space and probably binds to a receptor. SUBCELLULAR LOCATION: [Proheparin-binding EGF-like growth factor]: Cell membrane; Single-pass type I membrane protein.
Protein: MIAB_SYNY3
Sequence: MNVSHRRYHIITFGCQMNKADSERMAGILENLGMTYTDDPNQADLVLYNTCSIRDNAEQKVYSYLGRQAKRKQVEPELTLVVAGCVAQQEGEQLLRRVPELDLVMGPQHANRLDQLLEQVWAGSQVVATESLHIMEDITKPRRESTVSAWVNIIYGCNERCSYCVVPNVRGVEQSRTPEAIYGEMEVLAQQGFKEVTLLGQNIDAYGRDLPGTTPSGRHLHTLTDLLYHVHDIEGIDRLRFATSHPRYFTERLIQACQELPKVCEHFHIPFQSGDNDILKAMKRGYTREKYLQIIEKIRRYMPDAAISADVIVGFPGETEAQFENTLNLIEEVGFDLLNTAAYSPRPGTPAAFWDNQLSEEVKGDRLQRLNHLVSTQAMERSQRYLGRVEEVLVEGENLKSPGQVMGRTRGNRLTFFQGEISELLGKTVPVKITEARAFSLTGEALSLVTA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRO1A_ACACA
Sequence: MSWQTYVDTNLVGTGAVTQAAILGLDGNTWATSAGFAVTPAQGQTLASAFNNADPIRASGFDLAGVHYVTLRADDRSIYGKKGSAGVITVKTSKSILVGVYNEKIQPGTAANVVEKLADYLIGQGF
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-1A, Acidic profilin IA, Profilin IA.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AKTP1_DROSI
Sequence: MTLDLDAHKKDDKLLITTIQQEYKILAEYKMIESEKLSGIYVIPSYANSLQWFGVFFGRQGLYAESVFRFTILLPDRFPDDKSLPTIIFQQDVIHPHVCPYTHSLDVSHAFPEWRCGEDHLWQLLKYLQVIFSDPLDSIRGIEVDKLKNREAAELLMNNKEEYVARVQENIKESKEHIFDTPPTEDPHYIVFEKFQQDVHGPVLERIKAGRSKQTEPSAQQGNGGHATGLSWVKEGEFKPLSIE
What are the official names of this protein?
Protein crossbronx.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
Protein: HEM3_RUMJO
Sequence: MKKIRIGSRDSKLAIIQSELIMSAIRKYDPDIELELITMKTTGDKILDKTLDKIEGKGLFVKELDNALYNNEVDITVHSYKDMPLEENPELPVVALSKREDPRDAFILPQNGENGEPIGSSSLRRQLQLKELFPGCKTAPIRGNVQTRLKKLDSGEFSAIVLAAAGIKRLGLESRIGRYFSVDEILPAASQGIIAVQGRVGENFDFLKLFHSEESLCISLAERTFVREMNGGCSTPIAAYATIQGSEIILKGLYCNETTGELRKECVSGNRNNPVELGYELVKKMKSSKSI
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: KPRB_PONAB
Sequence: MFCVTPPELETKMNITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTISKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVAAIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRLIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD
What is the function of this protein?
Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.
What are the official names of this protein?
Phosphoribosyl pyrophosphate synthase-associated protein 2, PRPP synthase-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
Protein: SYMC_DICDI
Sequence: MSKPSNTPPLPKDGERNILITSALPYVNNVPHLGNIIGCVLSADVYARYCRLKNYNCIYICGTDEYGTATETKALSEGCTPKEICDKYHEIHKEIYEWFNISFDKFGRTSTNSQTEIAQDIFNKIKDNGYTLTQEIEQLYCEQTCKMFLADRFVEGTCPHCKFEDARGDQCDGCSKLLNPTELINPRCKVCSKPPVIKSTKHIFIDLPQLQQQVDQFVETNSKGGNWSENSIAITNTWVKGELKPRCITRDLKWGTPVPMEEFKDKVFYVWFDAPIGYISITAEYTNEWEKWWKNPENVKLVQFMGKDNVPFHTVIFPASLIGSKDNYTLLNNLSTTEFLNYETGKFSKSRNTGVFGDGAKATGIPSEVWRFYLLNNRPESSDSIFSWDDFNFKNNELLNNFGNLVNRVLKMLNTNAAFNGVVPKIGELNEVDKKLVQEVDEHLVQYFQKLEEISLKEGLKIAMSISKLGNTYMQDNKPWDLSGKDNERCGQVLAILINLIKLLSTLLEPYIPSLTDKVHQQLNVEPTKYSTHFDINAIPAGHEISKEILPLVKKIEADDLKKWRTKFSGIGPEFPIDMKIATVLEVNDHPSAENLYVIKLSLGGDQTKTAVSGIKANFEKSQLIGKKLAVVLNLKPSKFKGVLSEAMILVADDGQATKESLSFLVPSNPQSIEAGSKIAGKGMSIKPKPTIDYQKEFLHYDLTCIDKIISYNKSQLFINQNEPLVSEKIGNGKVR
What are the official names of this protein?
Probable methionine--tRNA ligase, cytoplasmic, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_BRUAB
Sequence: MVSFGGLARKIFGSSNDRRVKTLRQRAEQITALEKNYENLTDEQLQAKTAEFRAALAEGKSLDSLLPDAFATAREAAKRVLGMRPFDVQLIGGMVLHERGIAEMRTGEGKTLMATLPVYLNALEGKGVHVVTVNDYLATRDAETMGRLYNFLGLTVGVIKHGLDDDERRAAYACDITYGTNNELGFDYLRDNMKYERAQMVQRPHNYAIVDEVDSILIDEARTPLIISGPLEDRSDFYNLIDTFIPPLAEEDYEVDEKQKTAIFTEVGTEKVEKLLEAAGHLKGESLYDIENVAVVHHLNNALRAHKLFQRDKDYIVRNDEIVIIDEFTGRMMPGRRYSEGLHQALEAKEHVTIQPENQTLASITFQNYFRMYNKLSGMTGTAATEAEEFGNIYGLEVLEIPTNLPVQRIDEDDEVYRTVEEKYRAIVRDIRASHEKGQPILVGTTSIEKSEQLAERLRREGIKGFQVLNARYHEQEAYIIAQAGVPGAVTIATNMAGRGTDIQLGGNLEMRVRQELSDVPEGPEREEKIAAIKADIAQLKEKALAAGGLYVLATERHESRRIDNQLRGRSGRQGDPGRSKFFLSLQDDLMRIFGSDRMDGMLQKLGLKEDEAIVHPWINKALEKAQKKVEARNFEIRKNLLKYDDVMNDQRKVIFEQRLEMMDEEDLTETVAEMRHEVIEDMVILRIPKDAYAEKWDIAGLKQDIASKLNLDLPVEEWAKEEGIAEEEFENRIKEAADKAAAEKAERFGPQIMTYVEKSVIMQSLDNLWREHLVNLDHLRSVVGFRGYAQRDPLNEYKTEAFELFQTMLANLREVVISQLMRVEIVREAPPEPQLPPMAGLHIDGTTGENDFDEAIWAEHQHDDRIVPPAQRDPADPRTWGKVSRNEPCPCGSGKKYKHCHGAFE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RL15_XANC8
Sequence: MTMHLNDLKPADGARTERTRVGRGIGSGLGKTCGRGHKGSFARKGGGKIKAGFEGGQTPMQRRLPKIGFRSKMARDSAEVLSYQLDKLEAGEIDFAALRAANLVPSRAKKAKIVLKGELSKKFVLKGVAATAGAKAAIEAAGGSVEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RL5_MYCSK
Sequence: MTTAEKTLPRLKQRYREEIRESLQQQFGYANVMQIPGVVKVVVNMGVGDAARDAKLINGAVNDLALITGQKPEIRRARKSIAQFKLREGMPIGARVTLRGDRMWEFLDRLVAIALPRIRDFRGLNPKQFDGTGNYTFGLTEQSMFHEIDVDSIDRPRGMDITVVTSATTDDEGRALLRALGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GCST_LISMO
Sequence: MTELLKTPIHPLYAKYGAKTIDFGGWDLPVQFAGIKAEHEAVRTDAGLFDVSHMGEILVKGPDSTSYLQYLLSNDIEKIKIGKAQYNIMCYETGGTVDDLVVYKKSETEYILVVNAANTDKDFEWMVKNIRGDVSVTNVSSEYGQLALQGPNAEKILSKLTDVDLSSISFFGFVEDADVAGVKTIISRSGYTGEDGFEIYMPSADAGKVFEAILAEGVAPIGLGARDTLRLEAVLALYGQELSKDITPLEAGLNFAVKLKKEADFIGKEALIKQKEAGLNRKLVGIELIERGIPRHDYPVFLNEEQIGVVTSGTQSPTLGINIGLALIDTAYTELGQEVEVGIRNKKVKAKIVPTPFYKRAK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: YEBC_SHIDS
Sequence: MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPDANPRLRAAVDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECLSDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAEDVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMLPSTKADMDAETAPKLMRLIDMLEDCDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein YebC.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_VIBC3
Sequence: MALTKAELAEALFEQLGMSKRDAKDTVEVFFEEIRKALESGEQVKLSGFGNFDLRDKNERPGRNPKTGEDIPITARRVVTFRPGQKLKARVENIKVEK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ZC21A_HUMAN
Sequence: MEGLEENGGVVQVGELLPCKICGRTFFPVALKKHGPICQKTATKKRKTFDSSRQRAEGTDIPTVKPLKPRPEPPKKPSNWRRKHEEFIATIRAAKGLDQALKEGGKLPPPPPPSYDPDYIQCPYCQRRFNENAADRHINFCKEQAARISNKGKFSTDTKGKPTSRTQVYKPPALKKSNSPGTASSGSSRLPQPSGAGKTVVGVPSGKVSSSSSSLGNKLQTLSPSHKGIAAPHAGANVKPRNSTPPSLARNPAPGVLTNKRKTYTESYIARPDGDCASSLNGGNIKGIEGHSPGNLPKFCHECGTKYPVEWAKFCCECGIRRMIL
What are the official names of this protein?
Zinc finger C2HC domain-containing protein 1A.
What is the protein family that this protein belongs to?
Belongs to the ZC2HC1 family.
Protein: O163_CONMR
Sequence: MKLTCMMIVAVLFLTAWTLVTADGTRDGLKNRFPKARLEMKNSEAPRSRGRCRPPGMVCGFPKPGPYCCSGWCFAVCLPV
What are the official names of this protein?
Conotoxin MaIr193.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RRT5_YEAST
Sequence: MTEQVNNDTTSDTTTTITTVYISNLPFTASERDLHAFLNNYGASSVLIPTQTVRRFSKRHNSNPRKPLGIAFAQFANNTLALKAIQDLNGTVFQNQKLFLKLHVPYEADSTPDTDVKKPKEKNKVKKTPETAADTVYCHDLPDDITDSEIRELFQLYSPQEIWIYRSKVYRRKCIPFAPHQITAALVTLQSETPIGDICDSVAKTATLRGKSIIVKPAYVSKIQEIKQLVKDNLTNARDPPPAALAEPAPAPAPVEPAEQVQEGQDNAETNDVPPPPASSSDRPTVAAT
What is the function of this protein?
May be involved in the modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription protein 5.
What is the protein family that this protein belongs to?
Belongs to the RRT5 family.
Protein: TP1_ODOHA
Sequence: MFTLKKSLLLLLFLGTINLSLSEQERNAEEERRDDPEEMDAEVEKRAILTTLANWARKFLGK
What is the function of this protein?
Has antimicrobial activity against some Gram-positive bacteria and fungi but has no activity against a range of Gram-negative bacteria except P. faecalis.  Active against the Gram-positive bacteria S. aureus ATCC 25923 (MIC=37. 5 uM), S. carnosus KHS (MIC=37. 5 uM), B. licheniformis X39 (MIC=19 uM), R. rhodochrous X15 (MIC=4. 8 uM), is virtually inactive against E. faecalis 981 (MIC=150 uM) and inactive against E. faecium 091299.  Has some antimicrobial activity against the Gram-negative bacterium P. faecalis X29 (MIC=75 uM) and is inactive against E. coli, P. aeruginosa and S. typhi.  Has antifungal activity against C. albicans ATCC 2002 (MIC=19 uM) and lower activity against the slime mold 090223 (MIC=75 uM).  Has low hemolytic activity against human erythrocytes (LC(50)=75 uM).
What are the official names of this protein?
Temporin-HN1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
Protein: FTSZA_DICDI
Sequence: MSQFMIRYQIINLSKVFNSPKSLNFIKRYTTSTASTTTTTTNDDSNWISTPNITVCGIGGGGCNSVNNMINKELYGIDFVVANTDAQALAISCSRKMVQLGKTLTRGLGAGAVPEVGKKATEESIEELMNQIGDTQMLFVTAGMGGGTGTGGAAVIASAAKAKGILTVGIVTKPFHFEGKHRMKLAEQGLIELEKSVDSLIVIPNEKLMEQSQELYIGNAFQMVDDVLYNSIRGISDILVKPGLINLDFADVRSIMCNSGKALMGVGEGEGKGRDAIAANIALNNPLLENINISGAKGVLLNIAGSDLKLQEVDHIVSLVSSKVDPSANIIFGSTFDQQLEGKIRVTLIVTGMDQLIQQQQQQQKQTKIESQVEQKLHSTTIVDQELKPIEPQKSIIIEEEQEEQQQPKPIIPGIFVEQELLTTTTTANITPSQQKQESLTQNNIFSPPQQQQQQPSINLQPNYQQLYQQLYQQQQQQLQQQQPISFLKRLSNLFFTNGNNNKPYNNNKNTPGSNYE
What is the function of this protein?
Probably involved in mitochondrion division process.  When overexpressed, induces mitochondrial tubule formation.  Binds to and hydrolyzes GTP (By similarity).
What are the official names of this protein?
Mitochondrial division protein fszA.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PIMT_CHLTE
Sequence: MARERQEMVVELKRYGISNARVLDAFLTVRRHLFVDAQSRPYAYSDNAMPIGFGQTISQPYTVAYMTSLLVERVPSGKVLEIGTGSGYQAAILAELGYRVYTIERIAGLYAAAGRVLDALGLPVHPRLGDGTLGWPEEAPFDGIIVTAAAPREPHTLMSQLAEGGVLVVPIGDLGSQQMTVIRRRGERFEHEIFHNFAFVPLCGREGWADNNE
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NBS_NARPS
Sequence: MKGSLSHELEVSLPADQLWQVYSTLRLAQLSAELLPTVISKVEVEEGDGGVGTLLRVTYALGIPGMKYHKERFVKIDHEKRLKEALFVEGGHLDLGFSSYLIRLEILEKGHNSSVIKSTVEYEVDEEHAANASFATTDPFMIIGGAVSEHLLQKKSNCSIMLL
What is the function of this protein?
Catalyzes the condensation of tyramine and 3,4-dihydroxybenzaldehyde (3,4-DHBA) to form norbelladine, the common precursor to all Amaryllidaceae alkaloids such as galanthamine, lycorine and haemanthamine, and including haemanthamine- and crinamine-type alkaloids, promising anticancer agents.
What are the official names of this protein?
Norbelladine synthase, NpNBS.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
Protein: RS15_ALKEH
Sequence: MSLSAEQKGEIVKKHARTASDTGSPEVQVALLTARIQHLSGHFAEHKQDHHSRQGLLKLVSQRRKLLDYLKRKDRQRYLDLIENLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FBRL_SCHPO
Sequence: MAYTPGSRGGRGGSRGGRGGFNGGRGGFGGGRGGARGGGRGGARGGRGGRGGARGGRGGSSGGRGGAKGGAKVIIEPHRHAGVFIARGKEDLLVTRNLVPGESVYNEKRISVDSPDGTKVEYRVWNPFRSKLAAGILGGLDNIYIKPGARVLYLGAANGTSVSHVADVVGPEGLVYAVEFSHRSGRDLLNMAKKRTNVIPIVEDARHVQKYRMLVGMVDVVFADVAQPDQARIVALNAAAFLKNEGGVVISVKASCIDSTADAAVVFAREVKKMQEEKIKPQEQLTLEPYERDHCIIVGKYLRHQ
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins.  Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.  Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).
What are the official names of this protein?
rRNA 2'-O-methyltransferase fibrillarin, Histone-glutamine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Fibrillar region of the nucleolus.
Protein: PATR_MYCBP
Sequence: MTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLAAVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ
What is the function of this protein?
May catalyze the transamination reaction in phenylalanine biosynthesis.
What are the official names of this protein?
Putative phenylalanine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: RP1BL_HUMAN
Sequence: MREYKLVVLGSRGVGKSALTVQFVQGIFVEKYDPTIEDSYREQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL
What is the function of this protein?
Probable GTP-binding protein with intrinsic GTPase activity.
What are the official names of this protein?
Ras-related protein Rap-1b-like protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytosol. Note=May shuttle between plasma membrane and cytosol.
Protein: ACP5_ARATH
Sequence: MATSFCSSISMQAPFSATTTRFCLNKQATIFNNEKTNNLSFSLRRLMPARLAVSCAVKQETVEKVSEIVKKQLSLTDDQKVTAGTKFTELGADSLDTVEIVMGLEEEFGITMAEERAKEIATVQQAAELIEELVQEKTA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein 5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.