PharMolix/UniProtQA huggingface dataset:
Protein: ISCR_XENNA
Sequence: MRLTSKGRYAVTAMLDVALHSQEGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGRDAGRIFVAEVISAVDESVDATRCQGKEGCQGGDRCLTHALWRDLSERITSFLGSISLEELVKNQEVLDVADRQDSDKRRTPNGRPQETINVNLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: GRCA_ECOL6
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGFAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: MNMG_HAES1
Sequence: MFYTENYDVIVIGGGHAGTEAALATARMKLKTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEIDAMGGLMATAADKAGIQFRTLNSSKGPAVRATRAQADRVLYRQVVRIALENQPNLDIFQQEVTDIILEKDSVTGIETKMGLKFRAKSVVLTAGTFLAGKIHIGLENYAGGRAGDPASVNLAKKLRDLNLRVNRLKTGTPPRIDARTINFDILAKQYGDEKLPVFSFMGSVEQHPEQIPCYITHTNDQTHDVIRKNLDRSPMYTGVIEGIGPRYCPSIEDKVIRFSDRNSHQIYLEPEGLTSNEVYPNGISTSLPFDVQMKIVNSMKGLEKARIVKPGYAIEYDYFDPRDLKSTLETKAISGLFFAGQINGTTGYEEAAAQGLLAGINAGLFVQEKESWFPRRDQAYIGVLVDDLCTVGTKEPYRVFTSRAEYRLLLREDNADIRLTSIARKLGLIDDIRWARFNQKMENIELERQRLRSIWLHPRSEYLNEANEILKSPLIREVNGEDLLRRPEINYQILTALTPFKPAMEDKEAVEQVEIAIKYQGYIEHQQEEIERQKRHENTAIPANFDYKNISGLSNEVCAKLEQYRPISIGQASRISGITPAAISILLVNLKKQGMLKRGE
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPA2_YEAST
Sequence: MGTSSEVSLAHHRDIFHYYVSLKTFFEVTGENRDRSNSTRAQKARAKLLKLSSSQFYELSTDVSDELQRRIGEDANQPDYLLPKANFHMKRNQARQKLANLSQTRFNDLLDDILFEIKRRGFDKDLDAPRPPLPQPMKQEVSKDSDDTARTSTNSSSVTQVAPNVSVQPSLVIPKMASIDWSSEEEEEEQVKEKPNEPEGKQTSMDEKKEAKPALNPIVTDSDLPDSQVLARDITSMARTPTTTHKNYWDVNDSPIIKVDKDIDNEKGPEQLKSPEVQRAENNNPNSEMEDKVKELTDLNSDLHLQIEDLNAKLASLTSEKEKEKKEEKEEKEKEKNLKINYTIDESFQKELLSLNSQIGELSIENENLKQKISEFELHQKKNDNHNDLKITDGFISKYSSADGLIPAQYILNANNLIIQFTTRLSAVPIGDSTAISHQIGEELFQILSQLSNLISQLLLSADLLQYKDQVILLKASLSHAITSIRYFSVYGPVLIPKITVQAAVSEVCFAMCNLIDSAKIKSDSNGESTTSNEGNRQVLEYSSPTATTPMTPTFPSTSGINMKKGFINPRKPASFLNDVEEEESPVKPLKITQKAINSPIIRPSSSNGVPTTSRKPSGTGLFSLMIDSSIAKNSSHKEDNDKYVSPIKAVTSASNSASSNISEIPKLTLPPQAKIGTVIPPSENQVPNIKIENTEEDNKRSDITNEISVKPTSSIADKLKQFEQSSEKKSSPKENPIAKEEMDSKPKLSNKFITSMNDVSTDDSSSDGNENDDADDDDDFTYMALKQTMKREGSKIEKNNDSKLPANIVELDLHESPESVKIESPESIKEITSSEMSSEMPSSSLPKRLVEDVEPSEMPEKGASVESVRKKNFQEPLGNVESPDMTQKVKSLGMTGKAVGPESDSRVESPGMTGQIKSLNMAGKVVGPEADSRVESPGMKEQIKSLGMTGKITAQESIKSPEAARKLASSGEVDKIESPRMVRESESLEAVGNTIPSNMTVKMESPNLKGNTVSEPQEIRRDIASSEPIENVDPPKVLKKIVFPKAVNRTGSPKSVEKTPSSATLKKSGLPEPNSQIVSPELAKNSPLAPIKKNVELRETNKPHTETITSVEPTNKDANTSWRDADLNRTIKREEEDEDFDRVNHNIQITGAYTKTGKIDYHKIPVDRKAKSEAEVHTSEEDIDESNNVNGKRADAQIHITERKHAFVNPTENSQVKKTSHSPFLNSKPVQYENSESNGGINNHIKIKNTGETTAHDEKHYSDDDDSSYQFVPMKHEEQEQEQNRSEEEESEDDDEEEEDSDFDVDTFDIENPDNTLSELLLYLEHQTMDVISTIQSLLTSIKKPQVTKGNLRGESNAINQVIGQMVDATSISMEQSRNANLKKHGDWVVQSLRDCSRRMTILCQLTGDGILAKEKSDQDYADKNFKQRLAGIAFDVAKCTKELVKTVEEASLKDEINYLNSKLK
What is the function of this protein?
Involved in pheromone-induced morphogenesis and efficient mating, perhaps as a cytoskeletal protein.
What are the official names of this protein?
Protein SPA2.
What are the subcellular locations of this protein?
Cell tip. Note=Localizes to a sharp patch at the shmoo tip (mating projection) which corresponds to the site of polarized cell growth.
Protein: HIS8_YERPN
Sequence: MSQSNNVTDLARANIRALTPYMSARRLGGNGDVWLNANEYPLGTEYQLTTQTFNRYPECQPKHVIERYAAYAGLPPEQVLVSRGADEGIELLIRAFCEPGQDAILFCPPTYGMYAVSAETFGVERRTVPAQADWQLDLPAIANNLEQVKVIYVCSPNNPTGNLINPADLQAVLALAQGRAIVAIDEAYIEFCPQASVSNWLKDYPNLVILRTLSKAFALAGLRCGFTLANSDIIQLLLKVIAPYPLSTPVADIAAQALSPKGIEQMRQRVSEVRANRAWLQSALQDCACVEQVFTSESNYLLARFTASSSVFNALWDQGIILRDQNKQPGLANCLRITIGTRQECERVIAALAPLPGIDNSNNIDNQNKTYSQTSSIRKGTI
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ATPG_SHEPW
Sequence: MANAKEIKTKIASVQNTQKITSAMEMVAASKMRKAQDRMASSRPYAENMRKVIGHVAQGSLEYKHPYLEVREAKRVGYIVVSTDRGLCGGLNVNLFKKVVADVKKQREAGAEVEFCPIGARSVQFFNSFGGQVSAHASGLGDAPSLTDLIGTVRVMLEAYNEGKLDRLYVVFNKFVNTMTQTPVIEQLLPLPKSEEDEISHHWDYLYEPDPKELLDTLLVRYVESQVYQGVVENIASEQAARMVAMKAATDNAGELISDLELVYNKARQAAITQELSEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EFTS_SACD2
Sequence: MAVSASLVKELRERTGLGMMECKKALVETDGDIDVAIENLRKASGLKAAKKADRTAAEGVVAVKVAEDGSYGVMVEVNSETDFVARDAGFLAFVDTVVNKAFDTKATDVAALAGDEIESTRQALVQKIGENIGVRRVQLIEAGSGVVGAYLHSNNRIAVLTQLTAGDVELARDIAMHVAAVNPQVVNSADMPAEVVEKEKEIIKAQPDMEGKPAEIVDKMMVGRINKFLKENSLVDQPFVKNPEVTVGKLAKDAGAEVVGFVRFEVGEGIEKVEEDFAAEVAAQVAASKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_BURTA
Sequence: MANDYLFTSESVSEGHPDKVADQISDAILDAILAQDKYSRVAAETLCNTGLVVLAGEITTTANIDYIQIARDTIKRIGYDNTDYGIDYRGCAVLVAYDKQSPDIAQGVDRAHDNNLDQGAGDQGLMFGYACDETPELMPLPIHLSHRLVERQANLRRDGRLPWLRPDAKSQVTVRYVDGKPHSIDTVVLSTQHAPDIDLPALREAVIEEIIKPTLPADLIKGDIKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALIQVSYAIGVAEPTSVMVNTFGTGRVSDETITKLVREHFDLRPKGIIQMLDLLRPIYEKTAAYGHFGREEPEFSWEAADKALALAEAAGVEPAVQVA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T131L_MOUSE
Sequence: MAGLRRPQSGAYRRTAAAVNLLLGVFQVLLSCCRPGGAQGQAFEPLPNVVELWQAEEGELLLPTQGDSEEDMEEPSQEQSFSDKLFIGKGLHFQPSVLDFGIQFLGHPAAKLLYAYNPSRESEVVVNSVFTAARHFHVPPVHCRVIPAMGKASFRVIFLPTEEGSIESSLFINTSSHGVFSYHVSGVGTRRVSTEGSAEQLPNAYFLLPQVQSIQLSQTQAETTNTSLLRVQLECSLHNKVCQQLKSCSLGSDDALHLEMNIIVAVENSSKQPEENTQALLDHLSIVYVATDESDTSDESAVNMYVLHSGNSLIWIQDIHHFSQKNVLSLQFEPVLLSTSTTNFTKIASFTCKAGTSCDSGIMGLRKKKASPAMQACLSSPVVQGYFRTDASTAQFHIESHETATGVWSIWYRSHFDQSIVLKDVFVSKETKHILKVLSFRGPLFLPPGCWNIFSLKLAVKGIVLNLFTNVFLTTNTGAIFAIPLQIFSAPTKEGSLGFEVLAHCGMHYFMGKSKTENPNWERSLSLDRSTWDMDSELANKLYERWKKYKSGDACRRNVLGMSQFAFTKKSKETEPFVSFLPRVVPEPNLVLNFSATALRNSAVKYFVVRNPTPQPVSLQLLPLSLYPRPEAAVRLLHKWFGTDMQMVNLSTGEFQLTQACPYQGEPSEESSLGALHVHLQALETRRVGVVFTPADYGKVTSLILIRNNLTVVDMVGVEGFGAQELLKVGGRLPGAGGSLRFKVPESTLMDCHRQLKDSKQILSITKNFKVENIGPLPITVTSLKINGYNCQGYGFEVLDCHPFSLSPNTSRDISIVFTPDFTSSWVIRELTLVTAADLEFHFTLNVTLPHHMLPLCAEVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNGSSSSQQNGDPVAMISSHPHKSTCKNFLDTYSPSDKGRGKSCLPVGPSLSRLQNAAKRSPATYGHSQKKHKCSFYYSKQKPSASAASSANVTTEEKQTVTLASSLSVAKEDICTNVLSENWVSLRYASGINGSLQKNLTLPKNVLHKEESSLKNTVVTNTPSECSMKEGVHTYMFPKETDSKISENVAELKEQEPCPQKTSKKPPESTLPKTPPQYLQSDLPEVSRKHGNKQQAPVRSEVDSFEPVRAADAEPSSVRKTQGASPEDTCSEKQDTPSAEQEDPSRKRKLQERREGSTQALNWNKTRPCRRNKKRASAQASSSPRPSEQSEQRLVCSDVRSWCAQDGAGEKCKAGTEVSGSSPERREEDSYYQKSEKKCADKFCSDSSSDCGSSSGSVRASRGSWGSWSSSSSDCDRRPVVDIQHFLPPGDGVSPQNFPSEASVPLSLPQHVCSSTDVSVLPEFTESPCPGLPATPAGAGEEKGLYPPGGLWPSQPVCLTSSFNCPVENGAPGVSQEPTSIPDSSFIDWSASCEGQFPSVYCPLELNDYNAFPEENMNYTNGFPCSSKVQTDFIGHSTPSTWNTPASMPAAWGHASLVNSPSYLTSTRSLSPMSGLFGSIWAPQSEVYETCCPISPATEHATHMENQVMCKEYYLGFNPFRAYMNLDIWTSTANRNANFPLSRDSSYCGNM
What is the function of this protein?
In its membrane-associated form, antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6.  Regulates thymocyte proliferation.
What are the official names of this protein?
Transmembrane protein 131-like.
What is the protein family that this protein belongs to?
Belongs to the TMEM131 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Cytoplasm. Note=During intrathymic development, resides in punctate cytoplasmic structures in DN1 and DN2 cells. In DN3 cells, found in large crescent-shaped membrane structures, which preferentially localize in cell-to-cell contact zones.
Protein: ATP6_APILI
Sequence: MKLILMMNLFEMFDPSTSNNLSMNWLFMMLPIIIFPSIFWLIQSRIMFIMKTLMNFMYNEFKVVSKSKYQSNIIIFISLMLYIMITNIFSLIPYVFTLTSHLLLNMILSLTLWFSFLIYLIYNNYIMFLSHLVPLNSPVFLMNFMVIIELISLIIRPWTLSIRLSANLISGHLILTLLGIFISNFISILPINLMIQNMLLTLEIFMSMIQSYVFSILLILYFSESN
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BENE_ACIAD
Sequence: MTTLLKTLKQDWSLSATIAGFLAVLISYSGPLIIFFQAAQKAHVSTEMMISWIWAISIGAAVTGIFLSIRFKTPVVTAWSAPGTALLVTLFPNISLNEAVAAYITAAIVIFLVGITGYFDKLLKWIPQGIAAGMMAGILFQFGLGLFLATDTLPLIVFSMLLCYLISRRFSPRYCMLWVLICGVAFSFFLGKMNPVPLDFQIARPQFIAPEWSWFSTLNLALPLILVSLTGQFLPGMAILKLSGYNTPAKPIIAAASLASLFAAFAGGITIVLASITATLCMGKDAHELKDKRYIAGIANGLFYVLGGVFAGSIVALFSLLPKELVAALAGLALLGAIASNIKIAMQEDQQRDPALITFLATVSGMHFLGLSSVFWGMCIGMLAYFILLKPKAS
What is the function of this protein?
Probably involved in the transport of benzoate.
What are the official names of this protein?
Benzoate membrane transport protein.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURB_RAT
Sequence: MADGDSGSERGGGGPGSFQPAPRGGGGPGGEQETQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGGGGFGGGPGPGGLQSGQTIALPAQGLIEFRDALAKLIDDYGGEDDELAGGPGGGAGGPGGGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGGAFCRYADEMKEIQERQRDKLYERRGGGSGGGDESEGEEVDED
What is the function of this protein?
Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene.  Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts (By similarity).  Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element.  Modulates constitutive liver galectin-3 gene transcription by binding to its promoter.  May play a role in the dendritic transport of a subset of mRNAs.
What are the official names of this protein?
Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B.
What is the protein family that this protein belongs to?
Belongs to the PUR DNA-binding protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPO4_BACAN
Sequence: MREMYPKKGRVILHVDMNCFFASVEIAHDSSLQGKPLAVAGNEKERKGIIITCSYEAREYGIRTTMPLWEAKRLCPQLIVRRPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLDITDCYALGSPLEIAKMIQQALLTELQLPCSIGIAPNLFLAKTASDMKKPLGITVLRKRDIPEMIWPLPVGAMHGIGEKTAEKLNDIHIQTIEQLAKGNEHIIRAKIGKHGVDLQRRAKGMDDREVDPSQMGQHKSVGNSMTFSKDMDEEKELLDMLQRLSKSVSKRLQKRTLVSYNIQIMIKYHDRRTVTRSKQLKNAIWEERDIFQAASRLWKQHWDGDSVRLLGVTATEIEWKTESVKQLDLFSFEEDAKEEPLLAVIDQINDKYGMPLLQRGSQLLRKQEKSFQQKLESKFM
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_LIMRD
Sequence: MLTQRQKKILQAIVRQYTSTGQPVGSKHLAEKLPFKVSSATVRNEMAVLEDNDLILKEHSSSGRIPSKRGYRYYVDNLLDPQAVTDNDLVVIQNSLGNGFQKIDEIISHSADILSNLTSYTAFTLKPEQESVRLSGFRVVPLGNHKVIAILVTDSGEVENQSFTLPPDIDTDAMQAVIRMINDQLVGLPLSEVVKRLKDDIPLQVLHYMHSPDGFLDIFDNVLSQAARERFFVGGRLNLLDFASTHDPHAIQSLYGLLDKNDNLSNILDSTLTSDNGVNVKIGQEISKNKLLDDYSLITASYNVEQYGRGIIAVLGPTRMPYSRTIGIVNAFRQELAKRLLDFYRHYYDS
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: AP3M1_CHICK
Sequence: MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAIDVENVPPVISTPLHYLISIYRDKIFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSETAIKDNVVIVYELLEEMLDNGFPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAYFDVIEEIDAIIDKSGSTVFAEIQGVIDSCIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHLISFKENSSSGRFDVTIGPKQNMGKTVEGVVMTVHMPKAVLNMNLTATQGSYTFDPVTKVLAWDVGKITPQKLPNLKGIVNLQSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYITKAGKFQVRT
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated.  The complex is associated with the Golgi region as well as more peripheral structures.  It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity).
What are the official names of this protein?
AP-3 complex subunit mu-1, AP-3 adaptor complex mu3A subunit, Adaptor-related protein complex 3 subunit mu-1, Mu-adaptin 3A, Mu3A-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: FADA_ECOHS
Sequence: MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGISREMQDAFAARSHARAWAATQSAAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEALATLRPAFDPVNGTVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCDPSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARISTTLLNLMERKDVQFGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNO1_RAT
Sequence: METQNTGTEDGFTPVTHRGGRRAKKRQAEQSSAAGQDGDAGRMDTEEARPAKRPVFPPLSGDQLLTGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKDTKDVSALTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
What are the official names of this protein?
RNA-binding protein PNO1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MNMG_BURTA
Sequence: MLYPIEFDVIVVGGGHAGTEAALASARMGAKTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAAATDEGGIQFRILNSSKGPAVRATRAQADRVLYKQAIRRYLENQPNLWLFQQAVDDLMVEGDRVVGAVTQVGVRFRARAVVLTAGTFLDGKIHVGLNNYTGGRAGDPAAVSLSSRLKELKLPQGRLKTGTPPRIDGRTIDFSKLEEQPGDLDPVPVFSFLGRPEQHPEQLPCWVTHTNERTHDIIRSGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIFLEPEGLTTNEFYPNGISTSLPFDVQLALVHSMRGLEQAHILRPGYAIEYDYFDPRALKSSLETKAINGLFFAGQINGTTGYEEAAAQGLLAGINAGRHALEKEAWCPRRDQAYLGVLVDDLVTRGVSEPYRMFTSRAEYRLSLREDNADMRLTEIGRELGVVDDVRWDAFNRKRDAVSRETERLRTTWVTPKTLPADEATELLGKPIDHEYSLAELLRRPGISYDGVCGLRGGECGPSEPLAEDALLLAQIKEQIEIGIKYQGYIERQAGEIERNGANENTRLPDGIDYTEVRGLSFEVSQKLNQFRPETIGQASRISGVTPAAISLLMVHLKKRGLGRRKGADSAPGADAETNSAATQQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM1_METMA
Sequence: MICRTIVEGTTKISVPVPPPDANFPPSAAPVFYNPEMELNRDINVAATAAFVERLLSKKDILREEIRYVDAFSASGIRGLRIAGEVGIHSTMNDWSHEAFELIKENIKINGLEEKAQATRRNANVLLHEQRFHIVDVDPFGTPSPYLDAAASSAYSMLSVTATDTAPLCGAHLNSGIRKYASVPLNTEYHSEMGLRVLLGACARELAKHEKGMLPLLSHVTRHYVRTYLEVLPGSRKADKTLKSMGFVAHCPRCGFRKPVYGLAVHIEKECPECGGLTKIAGPLWLGPYREPEFCNEVISELEAHPLNTKEKVRKIITFCRDELDIPMFYDQHVICKELGASATGIESLIEALRAGGFEASRTHFTGTSFKTDAPIAEIKKIILALSG
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: ATNC_EMENI
Sequence: MRYEELDEACRSLEHLASDAEAEGEDAPLIPDPPGAVSPPTSLSGKAVLQVILLCASATLTLDIGLTVVRAPKIRLFESILCQAYYRTHGNPLPVPMQNIPESQCKTKEIQSGVARLIGWQTVFDGIPAIFLAIPYGALSDSKGRRPVLLLCFLGLALSTAWALLVCWMQWPLELTWISSLFQCLGGGPAVATAVLEATIADVVPDDKRSTIYFQLQATVLISDILANPLSSVLMAHNAWTPCFLGVGIQALATVLLIALPETLDFAKGSRPSDASIYGCKEEEPTLRGCLAKNFRSIVSDRNVAGLVFSLLILTVSAESLDFLLQYVSQRYGWSIAQSAMLLSLRAVVEFGLLLVVGSLLLFTQSSGLRNPRQRDLLIARLSLGLIVAGLLILSLSPTVAPAILVYTLGAGFQPAIMSLLASLWKASNPSNLGSLYSTVAIILAVGGVISGPLISLMYRIGLSLGHGWVGLPYFVASGLCAGIAGVLLSVKLPEQEQKPRRRET
What is the function of this protein?
MFS efflux pump; part of the gene cluster that mediates the biosynthesis of aspercryptins, linear lipopeptides built from six amino acids including 2 highly unusual and nonproteogenic amino acids, 2-amino-octanoic acid (2aoa) and 2-amino-dodecanol (2adol) (PubMed:23248299, PubMed:27310134, PubMed:26563584).
What are the official names of this protein?
MFS efflux pump atnC, Aspercryptin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TATE_EDWTE
Sequence: MEGISITKLLVIAVLIVLLFGTNKLRTLGSDLGAALKGFKKAMNDETPAAKKSDGAEAAPRVENKE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatE shares overlapping functions with TatA.
What are the official names of this protein?
Probable Sec-independent protein translocase protein TatE.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family. TatE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MURG_CROS5
Sequence: MARLLIAASGTGGHVFPALGVAEKLSDYEIQWLGTPNRLEQSLVGDRYPFHTISVEGFQTRSPIKKLKILLGLLSSIFEVKQLIEQQKIDVVFTTGGYIASSAILAAKLSGIPAILHESNYIPGKVTKLLSRFCTTVALGFEGTKQYLPTTPTIWVSTPVRSQFYTSQPLDLNIPNDVPLIVIIGGSQGAVSVNQLVRQCVPYWLEMGAYVVHLTGKNDPNANSLQDPQYITLPFYDNMAGLLQRADLAVSRAGSGTLTELAITKTPAILIPYPFAAEDHQSFNAQVFVDAGAAYCYQQKELTDKILTDLVSDLLNHPDKLKEMSNKSSELAVMDSSEKLAKLIRDSI
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RTC5_PENRW
Sequence: MGAGQSNEHGASSPEELSSVLAERFAAKCFTPLELTHFKDNFFSRALEQGGLRYWNEKVLSDFLGIPDGICTSSPKQPLDAGPVIFRMVSYLGAFPFQNTLAPSVLTFEAMVKVVVLLTERYGKALKRGDKDRIKLLFGSLADVGRKIPAESNKESTTEDSETLVGHSHAPGFSVDEPANDEYDEDEDDDLALAALESLDAIEVFKHDHRVDKTVYETRISIDTFRRLLMLLLVIAPLKPLESLKAYTTGLDARRMESVKKEADSIIAAFTPEESDGGISYKAFARTISLSLPYLFDPLTALFEHMLFSKNLNLSQRSYKGPATETEQEESENEENENKGPPSPPPASLTLPGSFESAILNPTLTSHLSFFLPSTSSDINILRSSVKLHPVFSTAAHGSSLTYFSHHVLTWQSATLLILQGSLADSASEEVITLGAYIPQPWKTSTSTSSLSSKTSDLLPCLFQLSPKHLFLPGNPSSSAKKPNTPTAYFSSNTGIAIGCQIPAPSRTHQTYPTPHGAGSLIIDSNIETAEFHAAPVGHDGVFLPAANASLEDPPTKLKLDLYTLEIWGIVPDPEASFSADPNLSPVEIQRAKWEFEAREAERRRNINIKAGAGDSAAESARWLLETAGIIGDDARYVGGRG
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.