PharMolix/UniProtQA huggingface dataset:
Protein: CYB_BALBR
Sequence: MTNIRKTHPLMKIVNDVFVDLPTPSNISSWWNFGSLLGLCLITQILTGLFLAMHYTPDTTTAFSSVAHICRDVNYGWVIRYLHANGASMFFICLYAHMGRGLYYGSYAFRETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAMVHLIFLHETGSNNPTGIPSDMDKIPFHPYYTTKDILGALLLILTLLMLTLFVPDLLGDPDNYTPANPLSTPTHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILALIPMLHTSKQRSMMFRPFSQFLFWVLIADLLTLTWIGGQPVEHPYVIVGQFASILYFLLILVLMPVTSLIENKLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NPF_CORAP
Sequence: STQMLSPPERPREFRHPNELRQYLKELNEYYAIMGRTRF
What is the function of this protein?
May have an important physiological role in neuroregulation.
What are the official names of this protein?
Neuropeptide F, NPF.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: IP21_SOLTU
Sequence: RICTNCCAGYKGCNYYSANGAFICEGESDPKNPNVCPRNCDTNIAYSKCLR
What are the official names of this protein?
Proteinase inhibitor PTI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I20 (potato type II proteinase inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NNRD_STAA8
Sequence: MGGYITMETLNSINIPKRKEDSHKGDYGKILLIGGSANLGGAIMLAARACVFSGSGLITVATHPTNHSALHSRCPEAMVIDINDTKMLTKMIEMTDSILIGPGLGVDFKGNNAITFLLQNIQPHQNLIVDGDAITIFSKLKPQLPTCRVIFTPHLKEWERLSGIPIEEQTYERNREAVDRLGATVVLKKHGTEIFFKDEDFKLTIGSPAMATGGMGDTLAGMITSFVGQFDNLKEAVMSATYTHSFIGENLAKDMYVVPPSRLINEIPYAMKQLES
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ADP-dependent (S)-NAD(P)H-hydrate dehydratase, ADP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
Protein: SEM4F_RAT
Sequence: MLARAERPRPGPRPPPVFPFPPPLSLLLLLAILSAPVCGRVPRSVPRTSLPISEADSYLTRFAASHTYNYSALLVDPASHTLYVGARDSIFALTLPFSGERPRRIDWMVPETHRQNCRKKGKKEDECHNFIQILAIVNASHLLTCGTFAFDPKCGVIDVSSFQQVERLESGRGKCPFEPAQRSAAVMAGGVLYTATVKNFLGTEPIISRAVGRAEDWIRTETLSSWLNAPAFVAAMVLSPAEWGDEDGDDEIFFFFTETSRVLDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASGVLQAMAELRPQPGAGTPIFYGIFSSQWEGAAISAVCAFRPQDIRAVLNGPFRELKHDCNRGLPVMDNEVPQPRPGECIANNMKLQQFGSSLSLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPEPQPVESMKLYHDWLLVGSHTEVTQVNTSNCGRLQSCSECILAQDPVCAWSFRLDACVAHAGEHRGMVQDIESADVSSLCPKEPGEHPVVFEVPVATVGHVVLPCSPSSAWASCVWHQPSGVTALTPRRDGLEVVVTPGAMGAYACECQEGGAARVVAAYSLVWGSQRGPSNRAHTVVGAGLVGFLLGVLAASLTLLLIGRRQQRRRQRELLARDKVGLDLGAPPSGTTSYSQDPPSPSPEDERLPLALGKRGSGFGGFPPPFLLDSCPSPAHIRLTGAPLATCDETSI
What is the function of this protein?
Probable cell surface receptor that regulates oligodendroglial precursor cell migration (By similarity).  Might also regulate differentiation of oligodendroglial precursor cells (PubMed:21945643).  Has growth cone collapse activity against retinal ganglion-cell axons (PubMed:10051670).
What are the official names of this protein?
Semaphorin-4F, Semaphorin-W, Sema W.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic density. Perikaryon. Cell projection, dendrite. Note=Colocalizes with DLG4 at synapses.
Protein: DUS11_BOVIN
Sequence: MSQWHHVGGHWGQDRVFSGYSSAKKKGGNHIPERWKDYLPVGQRMPGTRFIAFKVPLKKSFEKHLAPEECFSPLDLFNKIQEQNEELGLIIDLTYTRRYYKPEELPENFPYLKIYTVGHQVPDDDTIFKFKNAVNGFLRENKDNDRLIGVHCTHGVNRTGYLICRYLIDVEGMRPDDAIELFSRCRGHCLERQNYIDDLRNGPIRKNWDSSVSRTRGFEDSTHMMEPVFTATKPVNRRPKHNIHQTQGYPEPRHFHTWTQDLQQSERKFSQNWNIYQRCHVPPPGPPGEDYFQRRYSWNVKPSAGQGGPNKRFSPGSYYRVPYSAYYRWTK
What is the function of this protein?
Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity.  In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro).  Binds to RNA.  May participate in nuclear mRNA metabolism.
What are the official names of this protein?
RNA/RNP complex-1-interacting phosphatase, Dual specificity protein phosphatase 11, Phosphatase that interacts with RNA/RNP complex 1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: RLMC_ACTP2
Sequence: MILNCPHFQQQDCVSCQWLEKPYATQLTDKEIDLKRLISPFILQNFTEILPPVQSSQKQFRNKAKMVVSGSVERPILGILKDQTDPQSGIDLCDCPLYPTEFEALFPILKDFIARAGLVPYNISKKKGELKYILITQSRYNQSIMLRFVLKSEQKRPLVERELPNLLAKLPKDSVVSLNIQPQHAAILEGETEIFLTEKTTIEENFNDIPLFIRPQGFFQTNPNVASQLYATAQNWIKDLAIQQFWDLFCGVGGFGLHCAKALQEKNENVQLTGIEISASAIASATKSAEQLQLKNITFASLDSAQFALNEKSATPDLVIVNPPRRGIGKPLAEFLNQLGTPYLIYSSCNARTMAQDFEALSNYSLQKVQLFDMFPHTSHYEVLTFLVKKS
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: HYAL1_MOUSE
Sequence: MLGLTQHAQKVWRMKPFSPEVSPGSSPATAGHLLRISTLFLTLLELAQVCRGSVVSNRPFITVWNGDTHWCLTEYGVDVDVSVFDVVANKEQSFQGSNMTIFYREELGTYPYYTPTGEPVFGGLPQNASLVTHLAHTFQDIKAAMPEPDFSGLAVIDWEAWRPRWAFNWDSKDIYRQRSMELVQAEHPDWPETLVEAAAKNQFQEAAEAWMAGTLQLGQVLRPRGLWGYYGFPDCYNNDFLSLNYTGQCPVFVRDQNDQLGWLWNQSYALYPSIYLPAALMGTEKSQMYVRHRVQEALRVAIVSRDPHVPVMPYVQIFYEMTDYLLPLEELEHSLGESAAQGVAGAVLWLSSDKTSTKESCQAIKAYMDSTLGPFIVNVTSAALLCSEALCSGHGRCVRHPSYPEALLTLNPASFSIELTHDGRPPSLKGTLSLKDRAQMAMKFRCRCYRGWRGKWCDKRGM
What is the function of this protein?
May have a role in promoting tumor progression.  May block the TGFB1-enhanced cell growth.
What are the official names of this protein?
Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted. Lysosome.
Protein: V1R43_MOUSE
Sequence: MSKILFFSPCSLFSHTMNKNSRLHTNSNIGNTFFSEIGIGITGNSFLLLYHILKFIRGHRPRLTDLPIGLLSLIHLLMLLVAAFIATDIFISRRGWDDIICKFLVYLYRVLRGLSLCTTSMLSVLQAIILSPRSSCLSKFKHISLHHILCAILFLSVLYMLISSQLLVSIIATPNLTTNDLTYVTQSCSILPLSYLVESINSTLLAIREYFLISLMFLSTWYIVALLCMHRKQTQHLQETRLSLKKSPEQSATQTILMLMTFFVLMTIYDNIVSCLRTMLLNDPTSYSIELFMIHIYATVSPFVFMSNEKHIVNFLRSMGKRMINLNLH
What is the function of this protein?
Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
What are the official names of this protein?
Vomeronasal type-1 receptor 43, Vomeronasal type-1 receptor A2, Vomeronasal type-1 receptor A5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENO_SHISS
Sequence: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAADKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL4_GEOMG
Sequence: MATIDVFDINKNKVGEMDLSDAVFNGDVREYLIHEAVKVQLANRRAGTVGVKNRAAVSGGGKKPFKQKGTGQARQGCIRAPHYVGGGVAFGPQAKTYALSMNKKARKAAVRSALSMLFKENKLSVLDCLSLPSISTKGFVGVLKTFDVTKTLVIIDEANTNLELSARNVKDVKVLKAEHLNVFDIVKFNNIILTQSAVRKIEGALQS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: APAG_MARMM
Sequence: MYEHESCGVRISVSPDYLEDESTPEEGRFVWAYTIEIENTGKQPVQLIARKWMITDANGRTEHVQGMGVIGEQPVIEPGGRFRYTSGAPLPTPSGFMSGSYEMRRGDGESFAATIPDFSLDRPSDRLWLH
What are the official names of this protein?
Protein ApaG.
Protein: MED4_CRYNB
Sequence: MAHTTPRSHPPPHSLLQNLTTQSLLLSHLFTLIASPPNPNTSTQTQLNQVYSALQLSTLDLSGLVKEVGHHQEAYRRLVEKKNEVAGLEMRVRGLVKRLEEGRKELEGMIDQGERSLEDIQKSEREPVPAKTLMAHAQSLSKHSSAPVSSLLAPVDKAQYAPWPTEMSMRMGLLFQLEGSMSGMGERGVVGEEQKAPQKVEERREHVEHEESGRRYDPNAVFQLDLNSDESDED
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 4, Mediator complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURT_ECOK1
Sequence: MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAEELQLPTSTYRFADSENLFREAVAAIGYPCIVKPVMSSSGKGQTFIRSAEQLAHAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQNVTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RMR1_ARATH
Sequence: MRLVVSSCLLVAAPFLSSLLRVSLATVVLNSISASFADLPAKFDGSVTKNGICGALYVADPLDGCSPLLHAAASNWTQHRTTKFALIIRGECSFEDKLLNAQNSGFQAVIVYDNIDNEDLIVMKVNPQDITVDAVFVSNVAGEILRKYARGRDGECCLNPPDRGSAWTVLAISFFSLLLIVTFLLIAFFAPRHWTQWRGRHTRTIRLDAKLVHTLPCFTFTDSAHHKAGETCAICLEDYRFGESLRLLPCQHAFHLNCIDSWLTKWGTSCPVCKHDIRTETMSSEVHKRESPRTDTSTSRFAFAQSSQSR
What is the function of this protein?
Involved in the trafficking of vacuolar proteins.  Functions probably as a sorting receptor for protein trafficking to the protein storage vacuole (PSV) by binding the C-terminal vacuolar sorting determinant (VSD) of vacuolar-sorted proteins.
What are the official names of this protein?
Receptor homology region, transmembrane domain- and RING domain-containing protein 1, AtRMR1, ReMembR-H2 protein JR700.
What are the subcellular locations of this protein?
Prevacuolar compartment membrane. Protein storage vacuole membrane. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Localizes mainly to the prevacuolar compartment of the protein storage vacuole, but a minor portion also localizes to the Golgi complex.
Protein: VF312_ASFB7
Sequence: MLLVKMTTHIFHADDLLQALQQAKAEKNFSSVFSLDWDKLRTAKRNTTVKYVTVNVIVKGKKAPLMFNFQNEKHVGTIPPSTDEEVIRMNAENPKFLVKKRDRDPCLQFNKYKISPPLEDDGLTVKKNEQGEEIYPGDEEKSKLFQIIELLEEAFEDAVQKGPEAMKTKHVIKLIQRKISNSAVKNADKPLPNPIARIRIKINPATSILTPILLDKNKPITLQNGKTSFEELKDEDGVKANPDNIHKLIESHSMHDGIINARSICISNMGISFPLCLEMGVVKVFEKNNGIDVNSIYGSDDISTLVNQIAIA
What are the official names of this protein?
Uncharacterized protein CP312R, pCP312R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus CP312R family.
What are the subcellular locations of this protein?
Virion.
Protein: Y1559_RALSO
Sequence: MQFDTRVLRQWNVPKLRALQRYALRRAGEDSLPQVAGSLTFTTVLSLVPILTVAFALFTAFPMFQSFRAAIEGYLFSNLVPGNISRPILTYLNQFSHNAKGLTAAGLVGLVVTSVMTMLTVENALNAIWRVRQRRPLAQRVLVFWALVSFGPVLIGASLSVSSYLVSVSAGYVAKLPYGLGVVVGLVPILLSAIAFAMLYVFVPNTLVAWRDAFLAGLVAAVAFEIAKRGFGYYVARFPTYTAVYGTFAALPIFLLWIYVSWLVTLLGATIAATLPIIRQGYWQRRAFPGSEFFDALGILLLLHRARDHAPRTLGELDIGRRLQLEADYVADLLIQLKTLHLVGKLQQDRGQAHWALLCDAHTTTLRPLYEKLVLSLPRLSRTAFAHQLGDTRVLEAQLHNPALDCTLEAVFASGEPGVVKAAAEAAAAPAAATLAASARA
What are the official names of this protein?
UPF0761 membrane protein RSc1559.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AAH1_SOYBN
Sequence: MYSATASNTFFLLSCFLLFCLLSAPSCVSMFSGIETGDLEKRDDLFPQILRDEAVARLYELGKVSDASGYLERTFLSPASMKAIDLIRKWMEDAGLRTWVDQMGNVHGRVDGANENAEALLIGSHMDTVVDAGMFDGSLGIVSAISAVKAMHVNGKLQKLKRPVEVIAFSDEEGVRFQTTFLGSGAIAGILPGTTLEISDKREVMIKDFLKENSMDITEESLLKLKYDPKSVWGYVEVHIEQGPVLEQVGFPLGVVKGIAGQTRLKVTVRGSQGHAGTVPMSMRQDPMAAAAEQIVVLESLCKHPEEYLSYDGHCSDSTVKSLSSSLVCTVGEISTWPSASNVIPGQVTYTVDIRAIDDLGREAVIYDLSKQIYQICDKRSVSCIIEHKHDAGAVICDSDLSSQLKSAAYSALKKMEGDIQDEVPTLMSGAGHDAMAISHLTKVGMLFVRCRGGISHSPQEHVLDNDVWAAGLATLSFLENLS
What is the function of this protein?
Involved in the catabolism of purine nucleotides.  Can use allantoate as substrate.  The sequential activity of AAH, UGLYAH and UAH allows a complete purine breakdown without the intermediate generation of urea.
What are the official names of this protein?
Allantoate deiminase 1, Allantoate amidohydrolase 1, GmAAH1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: CRLS1_RAT
Sequence: MLAWRVARGAWGSLRVAVRPPGARLGRGGSRRALLPPAACCLGCLAERWRLRPAAFALRLPGTSPRTHCSGAGKAAPEPAAGGDAAAQAPSARWVRASATSSYENPWTIPNLLSMTRIGLAPVLGYLILEEDFNVALGVFALAGLTDLLDGFIARNWANQKSALGSALDPLADKVLISILYISLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCCTAFTTAASAYSYYHYGRKTVQVIKGK
What is the function of this protein?
Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG).  CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
What are the official names of this protein?
Cardiolipin synthase (CMP-forming), CLS.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IHFA_CHRSD
Sequence: MGALTKADLAEHLHAELGFSKREAKSMVEAFFEEIRSCLRENEQVKLSGFGNFDLRDKRERPGRNPKTGEEIPISARRVVTFRPGQKLKARVEDFDESKVVH
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ARNA_ECOUT
Sequence: MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPRGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKSASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACAARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHYFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNARRCLNWEPKIDMQETIDETLDFFLRTVDLTDKPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: SYE_ACET2
Sequence: MDYKKLADMLFPHITKSVSYYEDVVFPARNLSPGAKVTRLAPSPTGFIHLGNLYGAFVDERLAHQSNGVFILRIEDTDDKRKVEGAVETIISSLEFFNLKFDEGAGINGETGNYGPYFQSNRAEIYQTVAKHLVEMGRAYPCFCSEEELEEIRKQQLAENVNTGYYGKWAVHRNLTLEEVQKHLENNESFVIRFKSMGNPEETFEIDDAIRGRLSMQVNFQDIVLLKANGIPTYHFAHVVDDHLMRVTHVVRGEEWLSTLPIHYELFTTLGWDLPVYCHTAHLMKIDNGVKRKLSKRKDPELGLEYYMQLGYHPAAVREYLMTILNSNFEEWRIQNPDSDINDFPFSLNKMSNSGALFDLDKLNDVSKNVLAKIPAEEIYEFLLKWAKEYKKEIVNLLEEHKDSVIKLLSVGRNSEKPRKDLIYCEQIFEFIKYFFDEYFAIVDKYPDNVDEEEAKKILKAYLETYDHNDDQTQWFEKIKVIATENGYAAKPKDYKKNPDMYKGHVGDVSTVIRIAIVGRSSSPDLWEIQQIMGEEKVRERIQRLL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRYAA_ARTJA
Sequence: MDITIQHPWFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKLQSGVDGGHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: SYE2_METPB
Sequence: MAASPLVRFAPSPTGFLHIGNARPALLNALFARRAGGRFLLRLDDTDRERSTEEFASAVAEDLGWLGITPDLFFRQSERTALYDTAAERLKAAGRLYPCYETPEELDRRRKRQLGRGLPPIYDRAALALSEADRAALEAEGRRPHWRFKLDHRVVAWNDLVRGESHVDCASLSDPVLVRADGSYLYTLPSVVDDAEVGVTDVIRGEDHVTNTGVQVQLFEALGAAIPAFGHHNLLTTADGEGLSKRLGHLSLRSLREAGYEPAAVRSLAVLTGSAEAVRPVASLDELASLVDLAHLSRAPARFDPAELDGMNARLVHEMPLDAVRERLAALGVPAEAADAFWAAVRANLGRVAEAADWWRVVAGPVTPVVSEPDFIARAARLLPEAPFDAGTWKAWTDAVKAETGAKGRALFMPLRLALTGLDHGPDLSALLPLIGRERAARRLAGETA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP6_ROTS1
Sequence: MNRLQQRQLFLENLLVGVNSTFHQMQKHSINTCCRSLQRILDHLILLQTIHSPVFRLDRMQLRQMQTLACLWIHQHNHDLQVMSDAIKWISP
What are the official names of this protein?
Non-structural protein 6, NSP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus A NSP6 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host mitochondrion. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: GAR1_ASHGO
Sequence: MSFRGNSRGGRGGARGGSRGGRGGFGGRQFQQGPPDSVVEMGAFMHDCEGDIVCRSINTKIPYFNAMIYLENKTEVGKVDEILGPLNEVFFTIKCAEGVKASSFKDGDKFYISPEKLLPIERFIPKPKVAGPPKPKRKRAAGGAPGRGGFGGRGGSRGGFGGRGGARGGFGGRGGARGGFGGFGGRGGSRGGFGGRGGARGGSRGGRGGKRF
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit GAR1, snoRNP protein GAR1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PR6AA_XENLA
Sequence: MASIWEETEADGLGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMRDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNMQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
What are the official names of this protein?
26S proteasome regulatory subunit 6A-A, 26S proteasome AAA-ATPase subunit RPT5-A, Proteasome 26S subunit ATPase 3-A, Tat-binding protein 6, TBP-6.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.