PharMolix/UniProtQA huggingface dataset:
Protein: SYDND_THIDA
Sequence: MRTHYCGAVTAADVGNTVTLCGWAHRRRDHGGVIFIDLRDREGMVQVVVDPDTPAAFKLAEDVRAEFVLKIEGKVRPRPAGTENPHLPTGMVEVLTLDLDVLNPSLTPPFQIDDETINENIRLQYRYLDLRREPMQKNLKLRYRVSKIMRDYLDTHGFMEVETPMLTRSTPEGARDYLVPSRVHDGMFYALPQSPQLFKQLLMVSGVDRYFQITKCFRDEDLRADRQPEFTQVDLETSFMGEEAIMGLVEGMIRDMMQKAQGIELPAAFPRMSYAEAMNRYGSDKPDLRVTLEIVDVGDVMRDVAFKVFATPANDPKGRVAALRIPGGATLSRSEIDGYTEFVKIYGAKGLAYIKVNDVGQLNEAGLQSPIVKNLSEAALHAVMERTGAQNGDLIFFGADRAKVVNDALGALRLKIGHEKGHVDGRAWAPLWVVDFPMFEYNEDENRWDALHHPFTAPKDGHEDWLATDPGKCLSKAYDMVLNGWEVGGGSVRIHREKVQEKVFAALNIGEEERREKFGFLLDALQYGAPPHGGLAFGLDRLVTLMAGAESIRDVIAFPKTQRASCLMTNAPNVVDEKQLRELHIRLRNPIAADKAA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T191B_HUMAN
Sequence: MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEDLEQHSRQLQEQWEELSSQLFYGGEPQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKVPPASPPPDLGRCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVLLTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT
What are the official names of this protein?
Transmembrane protein 191B.
What is the protein family that this protein belongs to?
Belongs to the TMEM191 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MT2_CAEEL
Sequence: MVCKCDCKNQNCSCNTGTKDCDCSDAKCCEQYCCPTASEKKCCKSGCAGGCKCANCECAQAAH
What is the function of this protein?
This protein binds cations of several transition elements.
What are the official names of this protein?
Metallothionein-2, MT-2, MT-Ce, Metallothionein-II, MT-II, Metallothionein-like protein.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 6 family.
Protein: REP3B_XENLA
Sequence: MVSGMICKAVVLVFGILYPAYNSYKAVRTKNVKEYVRWMMYWIVFALYTVTETIADLTVSWFPLYFELKIAFVVWLLSPYTRGASLLYRKFLHPLLSSKEKEIDDYIVQAKEKGYETMVNFGKQGLNLAANAAVTAAVKSQGAITERLRSFSMHDLTDVQGDETAETRFFPDGQKKPRASVSDSSGFSSLRKDSGDDRTDEDVEVNSEDEVYSQKGLRRSQSMRSVKVIKGRKEIRYGSLKHKPKKRPQLYF
What is the function of this protein?
Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis.  Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes (By similarity).
What are the official names of this protein?
Receptor expression-enhancing protein 3-B.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: G3PC_LEIME
Sequence: MVKVGINGFGRIGRVVFRAAQMRPDIEIVGINDLLDAEYMAYSLKYDSTHGRFDGTVEVIKGALVVNGKSIRVTSERDPANLKWDEIGVEVVVESTGLFLTQETAHKHIEAGARRVVMTGPPKDDTPMFVMGVNHTTYKGQPIISNASCTTNCLAPLAKVVNEKYGIVEGLMTTVHATTATQKTVDGPSLKDWRGGRGASQNIIPSSTGAPKAVGKVYPALDGKLTGMAFRVPTPNVSVVDLTVRLEKPATYKDICAAIKAAAEGEMKGILGYTDDEVVSSDFNGVALTSVFDVKAGISLNDHFVKLVSWYDNETGYSHKVLDLILHTSAR
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMDH_PONAB
Sequence: MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWLLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVTQKKVPDDCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVIAKHIPAYKLETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLRKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSAVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA
What is the function of this protein?
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis.
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein.
Protein: GCSP_XANC8
Sequence: MSQTPSSLRDLEHHSAFVERHIGPNDAEIAQMLGVVGHDSLDAMTDAIVPSNIKSPAALALPDAITEEEALARIRAIASKNQVQRTFIGQGYYGTHTPKVILRNILENPAWYTAYTPYQAEISQGRMEALINFQTMCADLTGMQIANASLLDEATAAAEAMTLAKRSAKSKSDTFFVHDAVHPQTQELLRTRAEPLGIVLRVGTPDEAMQAECFGVLLQYPDSFGHIGDHAALADAVHAQGGLVAVATDLLALTLIAAPGEWGADIVVGNSQRFGVPFGFGGPHAAFMACRDAYKRSMPGRLIGVSIDAAGNPAYRLTLQTREQHIRREKATSNICTAQVLLAVMASMYAVYHGPEGLTRIARRTHRLAAILAAALRSAGVTVGEHFFDTLHVKAIDADAIHAKAHAAGINLRAIDSEAVGISLDETSTRADVVALAQLFGAQADIDALDAATADALPQGMRRTSAFLQHPVFNTHHSEHELLRYMRSLADKDLAMDRTMIPLGSCTMKLNATAEMIPVTWPEFGAIHPLAPPEQSAGYAQLIEELEAMLVECTGYDAVSLQPNSGAQGEYAGLLAIRAYHRSRNEAHRDICLIPESAHGTNPASAQMCGMTVVVTKCDANGNVDVDDIRAKAEKYSDRLAALMITYPSTHGVFEEDVVAICEAVHAHGGQVYTDGANMNALVGVAKPGKWGSDVSHLNLHKTFCIPHGGGGPGVGPCAVKSHLAPFLPKTLPNAGIRAGENQKAAIHGSGSNFGEGEVGMVSAASYGSASILPISWMYVTMMGSAGLRKATQVALLNANYIAKRLSAHYKTLYTGRNGLVAHECILDVRPLEKTSGIGAEDIAKRLIDFGFHAPTLSFPVAGTLMVEPTESESQHELDRFIDAMIQIREEIRAIEDGRLDREDNPLKHAPHTATQVSASEWTHAYPRELAAFPLPSLKQQKYWPPVGRVDNVYGDKNVMCACIPVDAYKDDVVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: HUTH_BURL3
Sequence: MITLTPGHLTLPQLRQIARESVQLTLDPASFAKIDAGAKAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQKNLVLSHAVGVGEPMARSSVRLLMALKLSSLGRGHSGIRREVMDALIKLFNADVLPLIPVKGSVGASGDLAPLAHMSAVLLGVGEVFIRGERASALDGLRVAGLAPLTLQAKEGLALLNGTQASTALALDNMFSIEDLYRTALVAGALSVDAAAGSVKPFDARIHELRGHQGQIDAAASYRDLLAGSPINQSHLDCDKVQDPYSLRCQPQVMGACLDQMRHAADVLLVEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLALAASEIGALAERRIALLIDATLSGLPPFLVRDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATFAARKLADIADNTKHILAIELLAAAQGVDLRAPYHTSPKLAPVMETIRGKVAHYELDHYFAPDIAVIAKLVGERAFAKVAPFSFASEQ
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACT_COSCS
Sequence: VGMDQKDAYVGDEAQSKRGVLTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANKERMTQIMFETFNVPAMYVNIQAVLSLYASGRTTGCVLDSGDGVSHTVPIYEGYALPHAINRLDLAGRDLTDNLMKVLTERGYSFTTTAEREIVRDIKEKLTYVALDFDQEMKTAAESSQLEKSYELPDGNVIVIGNERFRCPEVRFQPSFIGMESSGIHDCTFKTIMKCDVDIRKDLYGNIVLSGGTTMFPGIGERMTKELTALAPSTMKIKVVAPPERKYSVWIGGSILASLSTFQQMWISKAEYDESGPSIVHRKCF
What is the function of this protein?
Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ETHA_MYCS2
Sequence: MTEHFDVVIVGAGISGISTAWHLQDRCPTKSYVILERRANIGGTWDLFKYPGIRSDSDMFTLGFRFKPWTSAKSIADGPSIWNYINEAAQENGIDKHIRTNHRVLGADWSDAENRWTITVEADGEQKQITASFLSVCSGYYNYDQGYSPEFPGADDFAGQIIHPQHWPEDLDYAGKKIVVIGSGATAVTLIPSLVNGGAAHVTMLQRSPTYIGSLPLVDPVAEKTNKYLPKNLAHFVNRWKAIAFSTAQYQLARKFPNYMRKTLMTMAQRRLPEGFDVQKHFGPRYNPWDERLCLAPNGDLFKTIRAGKADVVTDTIAKFTETGIKLTSGEELTADIIITATGLNMQLFGGASLTRNGQEVDLTETMTYKGLMLSGVPNMAITFGYTNASWTLKADLVSEFICRVLNYMDDNGFDRVEPQHPGDAVDALPFMDFNPGYFRRAMDSLPKSGSRAPWRLKQNYFFDLRMIRYDKVDEESLHFTKHRAAVSASSS
What is the function of this protein?
Is responsible for the activation of several thiocarbamide-containing pro-drugs, such as ethionamide (ETH), isoxyl (ISO) and thiacetazone (TAC), into reactive species.
What are the official names of this protein?
FAD-containing monooxygenase EthA, Baeyer-Villiger monooxygenase, BVMO, Prodrug activator EtaA.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
What are the subcellular locations of this protein?
Cell membrane. Note=Is most likely membrane-associated.
Protein: RL11_THIDA
Sequence: MAKKIVGYIKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAKTQGMEPGLPIPVVITAFADKSFTFIMKTPPATVLIKKAIKLDKGSSKPHTDKVGTITRAQLEEIAKTKEPDLTAADMDAAVRTIAGTARSMGIVVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: UREF_RHIME
Sequence: MAEHADTQSLLRLVTWLSPAFPVGSFSYSGGLEQAIHDRLVTGADDLRLWCETLLDHGTTWNDALLLAEGYRACDDAARLIAASELAEALAGSREWHMETMLLGEAFLAAAGHWPHASLEFPGARAAYPVAVGAVAGAHRTGLEAALAAFLNATISNAVSVAIRCGVTGQRDGVGMLARMEKTIGAVATRATRASLDDLGAATIIADIASLRHEILHSRLFRT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_GEOKA
Sequence: MRSFSFTKMHGLGNSYIYVDLFRETLPEEELPAIARSVADVHTGIGSDGLILICPSEKAPVKMRIFNSDGSEGKNCGNGLRCVAKYAYEHGIVSDRTFLIETLSGLVEARVAVADGEVTSVTVDMGEPRLERSAIPMLGPEAERVVAEPFAIAGGEYEITAVSMGNPHVIFYVDDIQKAPVTTLGPLVEKDPRFPEGVNVEFVEVVNERELHFRVWERGSGVTQACGTGACAAVVASVLNGKTARGEETVVHLAGGDLTIVWGHDGRVRMTGPAETVCTGVYYYRGGRNG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AXHA_ASPOR
Sequence: MKVTKKVLDQSLCCTALLALVGGAAAQCALPSSYSWTSTGALAEPKAGWAALKDFTNVVFNGQHIVYGSVADTSGNYGSMNFGPFSDWSEMASASQNAMNQGTVAPTLFYFAPKDVWILAYQWGPTSFSYKTSSDPTDANGWSAAQPLFSGTISDSDTGVIDQTVIGDDTNMYLFFAGDNGKIYRASMPIDNFPGDFGTQSEIILSDTKENLFEAVQVYTVDGQNKYLMIVEAMGANGRYFRSFTADSLDGEWTVQAGTESQPFAGKANSGATWTNDISHGDLVRNNPDQTMTVDPCNLQLLYQGRDPNASGDYNLLPWKPGVLTLQV
What is the function of this protein?
Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Releases L-arabinose from arabinoxylan (By similarity).
What are the official names of this protein?
Probable alpha-L-arabinofuranosidase axhA, Arabinoxylan arabinofuranohydrolase axhA.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 62 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARC_MYCS2
Sequence: MSESERSEGFPEGFAGAGSGSLSSEDAAELEALRREAAMLREQLENAVGPQSGLRSARDVHQLEARIDSLAARNAKLMDTLKEARQQLLALREEVDRLGQPPSGYGVLLATHDDDTVDVFTSGRKMRLTCSPNIEVKELKQGQTVRLNEALTVVEAGNFEAVGEISTLREILADGHRALVVGHADEERIVWLAEPLVAAKDLPDEPTDYFDDSRPRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVSYNDIGGLGRQIEQIRDAVELPFLHKDLYKEYSLRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAREAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIFSKYLTEDLPVHADDLTEFNGDRALCIKAMIEKVVDRMYAEIDDNRFLEVTYANGDKEVMYFKDFNSGAMIQNVVDRAKKYAIKSVLETGQKGLRIQHLLDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKSSSASRAIDTESNLGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Mycobacterial proteasome ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: CKT_CONTU
Sequence: GEEEYQKMLENLREAEVKKNA
What is the function of this protein?
Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors.  This toxin inhibits both NR2A/GRIN2A and NR2B/GRIN2B subunits of N-methyl-D-aspartate (NMDA) receptor-mediated calcium influx in central nervous system neurons.  Induces sleep-like symptoms in young mice and hyperactivity in older mice.
What are the official names of this protein?
Conantokin-T, Con-T.
What is the protein family that this protein belongs to?
Belongs to the conotoxin B superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAC_VIBC3
Sequence: MRIEQELKLGFKDVLFRPKRSTLKSRSQVNLTREFTFKHSGRQWSGVPVIAANMDSVGSFAMAKALAEHGVMTAVHKHYTVADWAEFVKSADKATLNNVMVSTGTSEADFQKTKDVMALSDELIFICIDIANGYSEHLVEYVQRVRAAFPDKVISAGNVVTGDMVEELILAGADIVKVGIGPGSVCTTRVKTGVGYPQLSAIIECADAAHGLGGRIIGDGGCTCPGDVAKAFGGGADFVMLGGMLAGHEEAGGELIVKDGETFMKFYGMSSKSAMDKHSGGVAGYRAAEGKTVLLPYRGSVHGTIQDILGGVRSTCTYVGAAELRELTKRTTFIRVQEQENNVYGRE
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: H32_CICIN
Sequence: MARTKQTARKSTGGKAPRKQLATKAWNTLATATGGVKKPHRFRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVAALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDMQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y3849_MYCBP
Sequence: MARTDDDSWDLATGVGATATLVAAGRARAARAAQPLIDDPFAEPLVRAVGVEFLTRWATGELDAADVDDPDAAWGLQRMTTELVVRTRYFDQFFLDAAAAGVRQAVILASGLDARGYRLPWPADTTVFEVDQPRVLEFKAQTLAGLGAQPTADLRMVPADLRHDWPDALRRGGFDAAEPAAWIAEGLFGYLPPDAQNRLLDHVTDLSAPGSRLALEAFLGSADRDSARVEEMIRTATRGWREHGFHLDIWALNYAGPRHEVSGYLDNHGWRSVGTTTAQLLAAHDLPAAPALPAGLADRPNYWTCVLG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase BCG_3849c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: DSBC_BORA1
Sequence: MKARIIVLLASLLCANAYAQNGYSASTAQSSGQNDTVYSTNQVGKPATNGGKVYSTTQVQPPDPVTDAVRKRFQLRFQDLKIGVVRPTPYGLFEVQLGGDMFYTDKDVSWVMKGPLIDAATRRDVTRENLEKLSAVSFSELPLDLAIKQVKGQGKHRIAIFEDPNCGYCKQLRHTLKEMDDVTIYTFLYPILSPDSTVKARDVLCAADPGKVLDAWMLEGKPPAPAHCRAPIEELVALGEKLRVRGTPTLFFEDNTRAAGVLPPAQLRERLTRNVSQ
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by transferring its disulfide bond to other proteins and is reduced in the process (By similarity).
What are the official names of this protein?
Probable thiol:disulfide interchange protein DsbC.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbC subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: IRAD_ECOUT
Sequence: MMRQSVQTVLPESTGNNTLSLRDSVCRDLFQLFSSPHSPLPILLVSGMPEWQGHNQSDKLLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHELAISLEMMLYHDDEPLTFDLVWQKGNWHRTMPQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraD.
What is the protein family that this protein belongs to?
Belongs to the GpW/Gp25 family. IraD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTC_YERPE
Sequence: MEQPSPVTRQSFDEWIVPTYAPADFIVVRGEGSTLWDQQGKSYIDFAGGIAVNALGHGHPAVRAALIEQADKVWHLGNGYTNEPVLRLAKQLIDATFAEKVFFCNSGAEANEAALKLARKYALDNFANKAGQQGEKNQIVAFRNAFHGRTLFTVSAGGQPKYSQDFAPLPGGIHHGIFNDLASAEHLITDQTCAVIVEPIQGEGGVLPADKEFLHGLRALCDRHNALLIFDEIQTGVGRTGELYAYMHYGVSPDVLTSAKALGGGFPIGAMLTTTKYASALSVGSHGTTFGGNPLACAVAGTVLSLINQPTLLAGVKARHQWFIDELAEINARHNVFAEIRGRGLLIGCVLNAQYAGKSKEIVQAAAQYGLIALIAGPDVVRFAPSLIISPKEIKEGLARLAMGIEQVCQKVTS
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, SOAT, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: MED8_XENTR
Sequence: MQREEKQLEACLDALISQVSDIKNSLVGFIHKLENEYDRLTWPSVLDSFALLSGQLNTLNKVLKNEKTPLLRNQVIIPLLLSPDRDEEIMRLTEGRVPVFSHEVVPDHLRTKPDPDVEELEKQLSAEAARITSEAAQKQVQSMNKMCSNLLDKISKEERESELGSLRQNKQTFNPTDTNALVAAVAFGKGLSNRRPPGQGGPMAPGQTGASSMLPNATGMQVPMSLPPNQQQQHMAGVSMSQGSQPGKMPSSIKTNIKSASMHPYQR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 8, Mediator complex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YTZL_BACSU
Sequence: MEQKILCEVNNCSYWGKGNKCTADAIYVVSHTGETAENSRETDCKTFKPHDL
What are the official names of this protein?
Uncharacterized protein YtzL.
Protein: TRIPC_XENTR
Sequence: MSSRPNNNPGGSLRRSQRNTAGAQPQEDTAGGRSNLEQAENKTHSLPESRKSHFKTPKVQSNTTSGPSKGHSSKRGCSSSNLLPNPEDTERINTTDTQRPKKDHVRGVKRSASPDHSRTNSPSSAKKPKALQHPEPSSGPRRPNNKPKKRQGSQEQPFPSASLPSTSKAHSRKGGSQGTSPLPKRKRTELSPCVKSSSAAVISTGAEDRPPKLSKLASKSATSAKAGCSNITDSSSSASTSSSSSAVASVSAAPPGARVKQGKDQNKARRSRSASSPSPRRSSREKEQTKTSSSSKFDWAARFSPKVSLPKTKLSLPGSSKTETSKPGPSGLQAKLANLRKSTKKRSESPPAELPSLRRSTRQKTTGSCASTSRRGSGLGKRAAAEARRQEKMADPDNQEGANSSAARTDETAQGAAASSSVAGAVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQATDESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSISPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASRDLLTNIQQLLVVTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCLEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYSRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNPVANANTTGHSELKRDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKNLAESEALLTSPPKVCTNGSGSLASTTTISTGSGTASGNSAADLGSPSLQHRDDSLDLSPPGRLSDVLKRKRLPKRGPRRPKYSPPRDEDKVDNQAKSPTTTQSPKSFLASLNPKTWGRLSTQSNSNNIEPARTAGVSGLARAASKDTISNNRERIRGWIKEQAHKFVERYFSSENMDGSNPALNVLQRLCNATEQLNLQVDGGVECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSDKDIVSRDIRLKRFLHVFFGTPLPGEEPLAKLDPTENRHLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGSRGSQALKFFNTHQLKCQLQRHPDCTNVKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGDHLLPYNMTVYQAVRQYSIQTEEERESTDDESNPLGRAGIWTKTHTIWYKPVREEEESAKDTVGGKRGRAQTAPTKTSPRNSKKHDELWHGKDGVCPRILNPLEVYLISGPPENITFDDPSLDVVILLRVLHAISRYWYYLYDNAVCKEIIPTSEFNNSKLTAKANRQLQDPLVIMTGNIPTWLTELGKSCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTVNREDLLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLPNPKGSQEGTKYIHNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDIPLGLPFYKWMLRQESSLATHDLVNIDPVVAKSVYHLEDIVRQKKRLEQDKAQTKESLQFALESLNMNGCSVEDLGLDFTLPGFPNIELKKGGKDVPVTIHNLEDYVRLVIYWALNEGVSRQLDSFRDGFESVFPLNHLQYFYPEELDQLLCGSRADPWDVKTLMECCRPDHGYTHDSRAVKFLFEILSSFDKEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFEATENPDDFLPSVMTCVNYLKLPDYSSIDNMREKLLMAAREGQQSFHLS
What is the function of this protein?
E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair.  Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.  Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spreading of ubiquitinated chromatin at damaged chromosomes.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIP12, HECT-type E3 ubiquitin transferase TRIP12, Thyroid receptor-interacting protein 12, TR-interacting protein 12, TRIP-12.
What is the protein family that this protein belongs to?
Belongs to the UPL family. K-HECT subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.