PharMolix/UniProtQA huggingface dataset:
Protein: CARB_PSECP
Sequence: MPKRTDLKSVLVIGSGPIVIGQAAEFDYSGTQALRVLKEEGLRVILVNSNPATIMTDPEFADATYIEPITPEVVEKIIAKERPDAVLPTLGGQTALNTAIALDKNGVLEKYNVELIGANIAAIELGEDREKFKGVVERCGAESARSHIIHTMDEALEAAKDLGYPMVVRPSFTMGGLGSGLAYNEDDLRRIVGQGLQYSPTSEVLLEESILGWKEYELEMMRDKNDNVVVVCSIENFDPVGVHTGDSITVAPALTLTDREYQKLRDVSIAVIREVGVDTGGCNIQFAIDPATGRVVVIEMNPRVSRSSALASKATGFAIAKIATKLSLGYTLDEIPNDITQKTPASFEPTLDYVVVKVPRFAFEKFPAADNTLTTTMKSVGEAMAMGRNFTEALQKALRSLEQKGSQLDFSSVPEYEVAELIEKAKRPTTDRLYQVQRALLGGATVEQLFEATKIDPWFLDQLELLNEVSREIRQAGALTTDMLQRAKRHGFSDEQIGALTHNSEAVVRGVRQALGIRPVYKTVDTCAAEFAAYTPYHYSAYDEEDEVALHSKPSILILGSGPNRIGQGIEFDYSCVHASMALRKAGYETVMVNCNPETVSTDYDVSTRLYFEPLTLEDVLEVIAAEERTGGVMGVFVQLGGQTPLKLAQQLADAGVPILGTSPEAIDLAEHRGAFSRVLDKAGLVSPKNGTAVSFEDAKKIADEIGYPVLVRPSYVLGGRGMEIVYDEPNLSRYIANATEITPDHPVLIDRFLEDAVEIDVDALFDGTDMYLGGIMEHIEEAGIHSGDSACVLPPITLGSNVVERVRTATRAIAEGVGVRGLINIQFALASDVLYVLEANPRASRTVPFVSKATGVQMAKAAALIGTGVTINQLRTAYKMLPETGDGSTLPLDAPVAVKEAVLPFSRFRTPEGKVVDSLLGPEMRSTGEVMGIDKHFDTAFAKSQAGANNALPTEGKVFVSVANRDKRSVIMGVKRLSDLGFEIVSTGGTADVLRRNGIAATPVRKVAEGSSAEGEGTIADLVVAGEIDMVFNTPSGGEARSDGYELRAAATSIGIPCITTVAEFNAAVQAIEAMRTYEWSVTSLQEHAAALGESQKAAAAKADLQHA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RL36_CHLTB
Sequence: MRVSSSIKADPSKGDKLVRRKGRLYVINKKDPNRKQRQAGPARKK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ISPH_SALTI
Sequence: MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRQRGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPEDVWTLNVKNEGKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQADVVLVVGSKNSSNSNRLAELAQRMGRTAFLIDDAADIQEAWVKDAACVGVTAGASAPDILVQNVIARLREFGGGEAVTLEGREENIVFEVPKELRVDVREVE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PP173_ARATH
Sequence: MSATRSTFLGSIFRTAKARILISPIARRSLPSPNFTSSRFHTSSSLRQSRIEGSIPRSFLPSIHVRFHSVSASTWFSSRRTSSQGRLASVSMYIQYSTSVPTRSLRRRISNRKKSSAKPILNVSKFHETISKLPPRFTPEELADAITLEEDPFLCFHLFNWASQQPRFTHENCSYHIAIRKLGAAKMYQEMDDIVNQVLSVRHIGNENLYNSIIFYFTKAGKLIRAVNIFRHMVTSKNLECRPTIRTYHILFKALLGRGNNSYINHVYMETVRSLFRQMVDSGIEPDVFALNCLVKGYVLSLHVNDALRIFHQMSVVYDCEPNSFTYDYLIHGLCAQGRTINARELLSEMKGKGFVPNGKSYNSLVNAFALSGEIDDAVKCLWEMIENGRVVDFISYRTLVDESCRKGKYDEATRLLEMLREKQLVDRDSYDKLVNVLHKDL
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g27800, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YIDD_STRP1
Sequence: MKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGTKGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PKAB_STRCO
Sequence: MARKIGSRYTAHQILGRGSAGTVWLGEGPDGPVAIKLLREDLASDQELVSRFVQERTALLGLDHPHVVSVRDLVVDGNDLALVMDLVRGTDLRTRLDRERRLAPEAAVAVVADVADGLAAAHAAGVVHRDVKPENVLLDMQGPLGPGGSHPALLTDFGVAKLIDTPRRTRATKIIGTPDYLAPEIVEGLPPRAAVDIYALATVLYELLAGFTPFGGGHPGAVLRRHVTETVVPLPGIPDELWQLLVQCLAKAPASRLRASELSARLRELLPMLAGMAPLDVDEPDAEQPEDAPDASAASPAAPVSTAEPVRRRGAVPLVPGAKPADSNRDTHTSMRVPAPDELAGGARGTARAPRASGAPRPGSARNRAATRRRRIAVGAGAVALVAAIGVGTWLATGGDEDGGGPQDTRNSAPAAP
What are the official names of this protein?
Serine/threonine-protein kinase PkaB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: GNMT_HUMAN
Sequence: MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKFRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD
What is the function of this protein?
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate.  Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine.
What are the official names of this protein?
Glycine N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTF3_MOUSE
Sequence: MSILFYVIFLAYLRGIQGNSMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQSTLPKAEAPREPEQGEATRSEFQPMIATDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLMEDYVGNPVVANRTSPRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3, HDNF, Nerve growth factor 2, NGF-2, Neurotrophic factor.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: MED14_DEBHA
Sequence: MSLLSIDDIFIPTSDLLNHSHNNKRLNYNQAKQTLLLNMNGSYPSSNNPISNGEPCDAKSNHLGGEMHNGVGSKLENGILKKAPDIPHITNNIIPLSNVLKFYTQEAYKQLTTAIENLSSTKDTENDSSRKKFFLNLIISLRQDFIKIYTLVKWASSSKDISKLIDLLNWFRSQDFYFEQLGYGLNELNRYSGAKLPNSDIITSLEVFIKKRPQLPSYNLISTPPISSEKTLEVLKDLNLTLMTRMALINNLPKRFINNYEIRDGRVYFTIQNEFQVSVTVGNDLIIEQEDDYYKSPFYFIDFKFLFGINPETALITHKDNKIITKLPKSSFQNLEKIVNTVLLNSGLGGLYDLLHKYSISFKLYLIARQLKDISINSKWRNNIQFKYQNGKSLILINYWSSHYLSRNWKSFIELGIDKNYNLNFRWFKNGTYELNHGISGIFDRNNIKKQSDASDEQQNNIEPNEESLEDLREDNNEDESEPQDLSVDLILNIIVNKHSEMLMDKIYETIVKRLSDQEEYCSFISCHQLLLKLTPNKSVVFAINPLTGFFYFIDPSPIQNQVTKKINTQSSNHKNKPFFSENDMVENIVNQLIQLKLEMFNKEINNKLITSGWINNEIIKLNDYETIKLSNFLNGDNFNNSNYNKIQFYRCKNWPLSWFLSNLVSGDNFRTFWWVARIKSIKGEWKIQWVQQLKFDQEMETSDELTLDYKFFNNLSSLCSNMIIDHMILEELQTKKIQYIQKQSKEKAAELLNKFQIDEVKEENIKPEETNNPFVYESIIMLYNDNRLLPVSNSSTSLFLKIKLITLNNSTQMKLKLFGNLRNIPNTLAETFNQLNLHISKSQNYFEINDIVNLSNKINDSSIKETRLLDSILLKLNVLNELIKVLYQLDQNNIEIVNSSIDSIQIKIDEESNNLTIKLPEMDEKFSLLSSNTESNEMKLIISYLNKYLSMTSKVQENEIIGIIKYFKEITPIVKTIKSVRATLDEKNKMKLSNGLSKLNFDVEFQNLNLIQFVYFLNHTNVNSNKKILKDKIVIKLNFMRNRFNKQDRLLLKLSMKDNLNSRNLKYKKLFELIYKGISEVDTTNGSKITKLNYDFIVDSSLINELMIKITDAFILFLSDNA
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 14, Mediator complex subunit 14.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 14 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MEP2_ARTOC
Sequence: MHGLLLAGLAVALPLGVAGHPARPQTALSPRGIDVNAYRFTSTAKYNEHKTTSQMVQSFAYSKDDDYVATATKLVKSTFPNMTFRTVKDHYIGTNGIGHVHFKQTAHDIDIDNADFNVNIGRDGKVFTFGNSFYQGEMPKTNPMVKRDYSDPVKALHGAIKTLKIPVKPESAKAMPMDEVETFKFEGTSGALSEPKAKLVYIQKDGNLHLTWRVETDVGDNWLLSYVDSKESETVHNVVDYVASADYKVFAFGLNDPTEGQPSMIKDPWNTTGSGSPFTWHGDGKTDYTVTRGNNVAAQDNPSGGSQWENNYRPDSPQLSFVYDYSDQMEPEDYKDFAITQLFYTTNTFHDVLYSLGFTEEAGNFQVNNGNKGGKGNDFAICNAQDGSGTNNANFATPPDGQPGRMRMYTWTTSKPKRDGDLEAGIVIHEYTHGLSNRLCGGPANSNCLNDLEAGGMGEGWGDFYATAIRLKQGDTHDTDYTMGEWAANQKGGIREYPYSTNMQTNPYTYADVKGMREVHGIGTVWATILYDVLWNLIDDHGMGKNVMPKMVDGVPTDGRTLAMKLVLDGMTLMPCNPNFMQARDAIIDADMALTKGANKCSLMKAFAKRGLGSNTKPGKGYTNNFDMPSGC
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 2, Fungalysin MEP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NFI_ECOLC
Sequence: MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEVTRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFVDGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLAWVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRYTANQP
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_BURM7
Sequence: MLATDSDPIVAIATASGRGGIGVVRLSLGRAGEAAARALSDALCGARLMPRHASYVPFLDGAGEPLDRGIALYFPAPHSYTGEHVIELQGHGGPIVLQLLLQRCLDAGRAHGLRLAEPGEFTRRAFLNDKLDLAQAEAVADLIEASTEAAARSAGRSLDGAFSRDIHALVDDVIALRMLVEATLDFPEEEIDFLEAADARGKLAHIRERLAHVLGDARQGALLREGLSVVLAGQPNVGKSSLLNALAGAELAIVTPIAGTTRDKVAQTIQIEGIPLHIIDTAGLRETEDEVEKIGIARTWGEIERADVVLHLLDARSGLGPGDEAIAARFPDGVPVVRVLNKTDLTGAPASVTRTGGGAARADVCEVRLSAKRGDGIDLLRGELLRIAGWQAGAESVYLARERHLIALRAAQAHLARAAEHAEQNAQALDLFAEELRLAQERLNSITGEFTSDDLLGVIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETI_BURMA
Sequence: MPKLGMREIRRAQLIDATLRSIDEAGLPGTTLASVAQRANISTGIVSHYFGDKDGLLEATMRHVLRDLWAATTRRRAAASDAPRARLRAVVAANFDDTQISAPVMKTWLAFWSQSMHEPTLRRLQRVNTRRLHSNLCAEFAKTLPRARAREAASGLAALIDGLWLRGALAGKPLDTKAALKLANDYIDQLLAPRV
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: MURD_HAEDU
Sequence: MMQNQYQGKIITIVGLGKTGLSCVAFFAEKQATIQVIDTREQPAGIEHLSDNVALHTGSLNLEWLLASDLIVMSPGLALATPEIQTAIQAGIEVVGDIELFVREAKAPIIAITGSNGKSTVTTLVSEMAQQAGIKVGMGGNIGIPALSLLNKGYELFVLELSSFQLETTYSLKAKAATILNVSQDHMDRYASGEHYRQAKLRIYENAEYVIVNDDDPLTYPLPSQSVGNLRHFAEHDAQYAIKYDQLCSGDQAVINTDQMLLTGRHNQLNALAAIALAEAAGINRTGIINGLRCYGGLAHRFQRVPTNDGVCWVNDSKATNVGSTVAALNGLPLSGTLYLLLGGDGKGADFSMLKALVNQPHIVCYCFGKDGKSLAELTTNSVLVDTMQQAIEQIRPLVKQGDMVLLSPACASLDQFNNFEERGDMFARLAQQAV
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_PSEA6
Sequence: MRIKDCILAIDQGTTSTRAIIFAPDSSIIAVAQQEFTQHYPNDGWVEHDPEDIWSSTVVVCRQAISEAIAKGARIAAIGVTNQRETTVVWDRNTGQAIYNAIVWQDRRTAKTCREMQDKGLFDVVNSRTGLLLDPYFSASKVAWILDNVEGAREKADAGDLAFGTIDSFLIWRLTDGQVHATDVTNASRTNLFNIHDMAWDPKLLEVFNVPKSVLPMVKECADDFGHTTEDLFGFSLPILGVAGDQQAASIGQCCFKEGAIKSTYGTGCFVMLNTGTKAFNSKNKLLTTVAYTIKGETHYALEGSIFIAGAAIQWLRDGLGVIKSASETEDLAKSLDDDHGVYMVPAFAGLGAPHWAPDARGAVFGLTRGTTNAHFVRAALESVCYQTSDLLHAMAEDGVSLDKIRVDGGMVGNNWLCQFLAGILDVTVERPKIMETTALGAAYLAGLKAGIYASCEQLASMNEVESSFDAKMPSSQRRKLIAGWENAVQSTLGYTK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: YM54_YEAST
Sequence: MNKLRDKFVDSTVEEERLRENRNHEKYWYRWGPYLSERSWATVREDYSLNGDAWSNFPFEHANARVFRWGEDGLFGVSDNKQLVCMNVALWNGKDERLKERLFGLTGPQGNHGEDVKELYFYLDNTPTHSYMKALYKYPFKKAFPYKELVQKNGERGYEDKEFEVYDIDGLYRDSETGDNPYFDVFFEMAKDDENPSELNFRLTIHNRSKIDSGELYIAPQLFFRNTWAFDGTRTKDKPLLERDAEAANLINMTHKKYGNCQMVFQPSPGGFSSGTNEEEEDKEVEDIDPLLLFTDNESNLVKLFNEEKNPSEYTKDAFEEYLVQGKTDAVNPENKGTKACAVYHFKNIPPGEYVTVRYKFTNDPKNSIFKAQNLAVVDEDEFDLIFDNREEEADNFYWRITPLPISDELRNLQRQAFSGLLWTKQFYNFTYDAWYNGDANVKPRPPPNRANGRNKNWKHLYIEDILSMPDKWEYPFFASWDTAFHCIPLAMIDPEFAKRQLDLLTREWYMHPNGQIPAYEWNFNDVNPPVHAWAVYRVFKIERNMYNREDRTFLERVFQKLLLNFTWWVNRKDTEGKNVFEGGFLGLDNIGVFNRSEPLPTGGTLEQADSTGWMAFFSLQMLNIALELAKENPVYEDIASKFFEHFILISDSMSFEYATDITGEKCKEVIKQNLWNEADKFYYDAISWGDHKVQLPIRSLVGLIPLYASMTLEPSIIKQFRGFKKRVDWFVNNRPEIFDRNIASMSKKGVGERLLLSLVTKERLTAILSRLLDETEFLSPYGIRSLSKYHEKHPFEMNVNGVEYMVKYLPGESDSGMFGGNSNWRGPIWFPTSFLIMEALQRFYLYYGSDFKVECPVGSGDYLNLAEVAEELGYRMIHLFVPDENGERAIHYGDHSKFLSSDPYFRDYVPFFEYFDGDTGRGLGASHQCGWTALVAKWISDVGISCVRLPRTPRSSVATTASTESSEQGPKMKRMARRKSAKSLVNYTATILDLTEEEKRHHRIGGTHSGLTPQSSISSDKARHLMEEMNEEEGIHETVVPEDRHNFETKLIGKLKDKVKNMKVTDKAKDEDIDPMDPMSPLNKDVS
What are the official names of this protein?
Uncharacterized protein YMR196W.
Protein: TCO2_PONAB
Sequence: MRHLGALLFLLGVLGALAEICEIPEVDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVDLRLSSLQAGTKEELYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRANCEFVRGHKGDKLVSQLKRFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYALEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAVRTVREKILKAQTPEGHFGNVYSTPLALQFLMTSPMPGAELGTACLKARVALFASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQAQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLISVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW
What is the function of this protein?
Primary vitamin B12-binding and transport protein.  Delivers cobalamin to cells.
What are the official names of this protein?
Transcobalamin-2, TC-2, Transcobalamin II, TC II, TCII.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic cobalamin transport proteins family.
What are the subcellular locations of this protein?
Secreted.
Protein: GREA_STRPJ
Sequence: MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDLSENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDEEEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RPOA_PROMP
Sequence: MLQYQIDRIDHQISDDRSQTGTFLIGPLERGQATTLGNSLRRVLMGGLEGSAVTAVRISGINHEYATIPGVREDVLDILLNCKQLSINSSNPETEIGRLVVNGPMEVKANDIQFSSQVEIVDGEKPIATIQEGHNLELEIHVERGVGYRPVDRRNQETTAIDLLQIDAVFMPVKRVNFTIDETAVAEGATGRERLTMEVVTDGSTSPDDAIAEAANQLIELFQPLATVTMVEEIPEEPEPSPEAQIPLEELNLSVRAYNCLKRAQVNSVSDLMGFSYEDLLEIKNFGSKSADEVIEALERIGISIPQSRTSV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: Y255_BRUC2
Sequence: MTADVPNARLVDVELDESIGRSTPDVEHERAVAIFDLIEENSFHPVGDQKGGPYRLKLSLMESRLIFSITRENGDAVATHILSLTPLRRVVRDYFMICESYYQAIRSATPSKIEAIDMGRRGLHNEGSQTLQARLKGKIEVDFDTARRLFTLVCVLHWRG
What are the official names of this protein?
UPF0262 protein BCAN_A0255.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: ABCH2_DICDI
Sequence: MAQVFPDVIEEKIQDDDKFFGQTRLKNDDIDFNDPDNVLTMKNIHKTYLLGIEGVPALRGVSMAIKRGEFICIFGTSGGGKTTMLNIIGTIDKPTKGEMKLCGKTINHKTTDKDLAFLRLRNIGFVFQTFNLLSSLTALENVEMPMILLGELSASERRERAISLLTKVGMKDRLDHFPSQLSGGEQQRVTIARAIANNPDVLLLDEPTGDLDTVNTSVIMKLLTDLNKQENITLIMVTHDVGLKMYSDRIIWMRDGKIQRIETVQEQSKREHYQKLYKECELINQNQKNGVTSVFKNDDDNKNIKKQGTLTEFRRPTDYKSIASYNNNNSNLNNNSNSNSNNNSNNNNSKNYASSSSSSSVLNGKLSQSTVNNSSIYNHNNDSPFFNSNNNNNINNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNSNSNNNNNNTKSNNNNNNNIFDIASSSSSYSNNNNNSKNNSLIDDIYLDINEGSSSNFSNNDNFKSVDQITNDLSRIL
What are the official names of this protein?
ABC transporter H family member 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: TPPP_CAEEL
Sequence: MAAAAGFNWDDADVKKRWDAFTKFGAATATEMTGKNFDKWLKDAGVLDNKAITGTMTGIAFSKVTGPKKKATFDETKKVLAFVAEDRARQSKKPIQDELDAITEKLAKLEAPSVGGAAKANAAGVYSRLTDHTKYTGAHKERFDAEGKGKGKSGRADTTENTGYVGAYKNKDSYDKTHGK
What is the function of this protein?
Regulator of microtubule dynamics.
What are the official names of this protein?
Tubulin polymerization-promoting protein homolog.
What is the protein family that this protein belongs to?
Belongs to the TPPP family.
Protein: AFOB_EMENI
Sequence: MAETDSSHTRGPVDSIQKNDASSDDAEAETKIQYPSGWRVTMILTSVTLAYFLFFLDLAVLSTATPAITSQFDSLVDVGWYGGAYQLGSAAFQPLTGKIYSQFSIKQWTFLVFFIVFELGSVLCAAARNSPMFIVGRVIAGVGSAGMSNGAVTTISAVLPTQKQALFMGLNMGMGQLGLATGPIIGGAFTTNVSWREDAPADDDAGFYINLPLGAVVGGFLLFNTIPEPKPKAPPLQILGTAIRSLDLPGFMLICPAVVMFLLGLQFGGNEHPWDSSVVIGLIVGGGATFGVFLVHQWWRGDEAMVPFALLKHKVIWSAAMTMFFSLSSVLVADFYIAIYFQAIRDDSPLMSGGAISAVGYGLLSTLSPTTSVAKWVGYQILYGVASGCTTAAPYVAIQNLVPAPQIPQAMAIIIFWQNIGAAISLIAANAIFSNSLRDQLAQRASQITVSPGAIVAAGVRSIRDLVSGSALAAVLEAYAEAIDRVMYLGIAVSVMVIVFSPGLGWKDIRKTKDLQALTSDGAQGEATEKETVPVALG
What is the function of this protein?
Efflux pump; part of the gene cluster that mediates the biosynthesis of asperfuranone, a probable antitumor agent (PubMed:19199437).
What are the official names of this protein?
Efflux pump afoB, Asperfuranone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DBH1_BIFLO
Sequence: MAYNKSDLVSKIAQKSNLTKAQAEAAVNAFQDVFVEAMKSGEGLKLTGLFSAERVKRAARTGRNPRTGEQIDIPASYGVRISAGSLLKKAVTE
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HB1.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: UBIX_RICPR
Sequence: MIKNKKIIIAISGASGAIYGIRLLKVLKEQNIETHLVISDGAALTIKFETKYSIQEVKFLANYCYDEKNLGAAISSGSFKTAGMIIAPCSMKTLASIAHSMEDSLISRAAGVVLKERRKLILMTRETPLHIGHLENMLKVAHYGGIIAPPIPAFYNKPTRINDIIDHSITRVLDFFDIETNLIKRWSSD
What is the function of this protein?
Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD.  The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
What are the official names of this protein?
Flavin prenyltransferase UbiX.
What is the protein family that this protein belongs to?
Belongs to the UbiX/PAD1 family.
Protein: PRP28_NEUCR
Sequence: MSTTSRREPPDLAALLRKKKEEEAAAAKPRFIPKKERERLEAEKKAKEEEERKRKEEAKPQPNGTNHNGNRMDGIQSHHNHNPQRNIPTGPKAMRYDDDRGPNGMSNGRDYRDNRDNRDNRDRNQRGAKRGAPNDDEEKRAKMERNDEAELRARYMGPVVNQSTFSAKKKRRRTAANKFNFDWDADDDTSRPFDPIYAERQEPLVRLGGYEMTEEMVMRKAEAIRRGDPETGEERARQYLEQHRRIKEMEQRKNLGKHWSEKKLEDMKERDWRIFKENFGIATKGGAIPNPMRSWEESTLPRRLLDIVKNVGYDEPTPIQRAAIPIALQARDLIGVAVTGSGKTAAFLLPLLVYISELPPLTEYNKNDGPYALILAPTRELVQQIESEAKKFATPLGFTVVSIVGGHSLEEQAFALRNGAEIIVATPGRLVDCLERRLLVFSQCCYTIMDEADRMIDQGFEEPLTKILDAMPVTNEKPDTDDAENPQLMSRYVDGKDRYRQTMMYTATMPPIVERIAKKYLRRPAIVTIGNAGEAVDTVEQRVEFVSGEDKRKKRLQEILNSGQFKPPIIVFVNIKRNCDMVARDIKGMGYSAVTLHGSKTQEQREAALASLRNGQTDILVATDLAGRGIDVPDVSLVVNFNMATNIESYTHRIGRTGRAGKSGVAITFLGPEDNDVLYDLRQIISKSSISKVPDELRRHEAAQNKPQKGQKKLEESNGYSGKGGSWN
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA splicing.  May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site.  May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing ATP-dependent RNA helicase prp-28.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: C2_CWPXG
Sequence: MESVIFSINGEIIQVNKEIITASPYNFFKRIQDHHLKDEAIILNGINYHAFESLLDYMRWKKINITINNVEMILVAAIIIDVPPVVDLCVKTMIHNINSTNCIRMFNFSKRYGIKKLYNASMSEIINNITAVTSDPEFGKLSKDELTTILSHEDVNVNHEDVTAMILLKWIHKNPNDVDIINILHPKFMTNTMRNAISLLGLTISKSTKPVTRNGIKHNIVVIKNSDYISTITHYSPRTEYWTIVGNTDRQFYNANVLHNCLYIIGGMINNRHVYSVSRVDLKTKKWKTVTNMSSLKSEVSTCVNDGKLYVIGGLEFSISTGVAEYLKHGTSKWIRLPNLITPRYSGASVFVNDDIYVMGGVYTTYEKYVVLNDVECFTKNRWIKKSPMPRHHSIVYAVEYDGDIYAITGITHETRNYLYKYIVKEDKWIELYMYFNHVGKMFVCSCGDYILIIADAKYEYYPKSNTWNLFDMSTRNIEYYDMFTKDETPKCNVTHKSLPSFLSNCEKQFLQ
What are the official names of this protein?
Kelch repeat protein C2.
What is the protein family that this protein belongs to?
Belongs to the poxviruses Kelch family.
Protein: RPGF4_RAT
Sequence: RVIRLVLQWAAMYGDLLQEDDVAMAFLEEFYVSVSDDARMMVAFKEQLAELEKTVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCIDHTDTTIRVPVAASVKEVISAVADKLGSGEGLIIVKMNSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTTGTVGTFELMSSKDLAYQMTTYDWELFNCVLELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKCIKIAAHCKEYKNLNSFFGIVMGLSNVAESRLALTWEKLPSKFKKFYAEFESLMDPSRNHKAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP.  Seems not to activate RAB3A.  Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).
What are the official names of this protein?
Rap guanine nucleotide exchange factor 4, Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, EPAC 2, cAMP-regulated guanine nucleotide exchange factor II, cAMP-GEFII.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.