PharMolix/UniProtQA huggingface dataset:
Protein: CP4AE_RAT
Sequence: MGFSVFTPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHDLKDREFQQVLTWVEKFPGACLQWLSGSKTRVLLYDPDYVKVVLGRSDPKASGIYQFLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYGILKPYVKIMADSVNIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLTFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKMRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQIPYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMARLVLKSKNGIHLRLKKLR
What is the function of this protein?
A cytochrome P450 monooxygenase that catalyzes omega and omega-1 hydroxylation of saturated fatty acids.  Exhibits preferential omega versus omega-1 regioselectivity and (R) versus (S) stereoselectivity for hydroxylation of dodecanoic (lauric) acid.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Cytochrome P450 4A14, CYPIVA14, Cytochrome P450-LA-omega 3, Lauric acid omega-hydroxylase, Long-chain fatty acid omega-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: IPRA_SAGSA
Sequence: MAASNALLLISGVLLISLAVLCHGDPVVDSDGDAVQLNLGGNYPLYTIQSAAIGFRGGLSTLHKDACKSYVYEAPETDRGLPVGFSASATSQPVMQLGSRYKFSFSMPVPLICDTAWSIGKSTEETGVYKLAACSCEFCKIACPEVGSFNVNGRTLLGIGGEHFTVRFQKFDALAMKTAPQ
What is the function of this protein?
Possesses two reactive sites.  Inhibits an equimolar amount of trypsin and chymotrypsin simultaneously, and inhibits kallikrein weakly.
What are the official names of this protein?
Proteinase inhibitor A, Double-headed proteinase inhibitor A, API-A.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROA_LIGS1
Sequence: MTVDLNKMGQAAREASRQLALLGEQKKNQVLETVAQELLAKADEIIAANKVDLENATNMPEKFIDRLKIDNDRIAAMAEGVRQVAQLADPIGKIDAGWVNYAGLQIEKKRVPLGVVGMIFEARPNVTVDASALCFKSGNAVILRGGKEALQTNIKITKVIRQALEQEGINPDAVQVITETSHELANEFMQLTDYLDVLIPRGSARLIQTVLNTAKVPVIETGAGICHVYVDKFADKKMAVEITTNAKVQRPSVCNAIENLVIHQDVAQEYLPAIADELQKYNVELRGDEKVCEILGDKATLATAEDWDTEYNDYIIAIKIVSSIDEAIDFINEHNTKHSEAIITENYTRSQKFLDEIDAACVYVNASTRFTDGFEFGFGAEIGISTQKLHARGPMGLEALTSTKYVIRGNGQIRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VDAC2_RABIT
Sequence: MATHGQTCARPMCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKLGLALELEA
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).  The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV (By similarity).  The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).  Binds various lipids, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol (By similarity).  Binding of ceramide promotes the Binding of ceramide promotes the mitochondrial outer membrane permeabilization (MOMP) apoptotic pathway (By similarity).
What are the official names of this protein?
Voltage-dependent anion-selective channel protein 2, VDAC-2, Outer mitochondrial membrane protein porin 2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Membrane. Note=May localize to non-mitochondrial membranes.
Protein: SAT_BACCZ
Sequence: MSTVNELVNLVDETYDISQIEKEIGLDNIALSDLELLATGGYSPLTGFLGKKDYDSVVETLRLANGSVWSIPITLPVTEEVAETLKVGEEVKLVNGGNVYGVIQIEDIFVPDKEKEALLVYKTTDEAHPGVKKLYERPNVYVGGAIVLTKRFENNPFPSYHLDPIETREEFKKRGWKTVVGFQTRNPVHRAHEYIQKSALEIVDGLFLNPLVGETKSDDIPADVRMESYEVLLQNYYPKNRVFLSVFPAAMRYAGPREAIFHALVRKNFGCTHFIVGRDHAGVGDYYGTYEAQEIFANFTVEELGITPLFFEHSFYCTKCEAMASTKTCPHGKEDHVILSGTKVRELLRNGEVPPSTFSRKEVVEVLIKGLKKEVVTE
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: KN7H_ORYSJ
Sequence: MGAAEEEAAAAWDKAEAKEERIMVSVRLRPLNGREAGDSCDWECISPTTVMFRSTVPERAMFPTAYTYDRVFGPDSSTRQVYEEGAKEVALSVVSGINSSIFAYGQTSSGKTYTMTGITEYSVLDIYDYIEKHPEREFILRFSAIEIYNEAVRDLLSHDTTPLRLLDDPEKGTTVEKLTEETLRDKDHLRNLLAVCEAQRQIGETALNETSSRSHQILRLTIESSTRQYLGRGNSSTLVACVNFVDLAGSERASQTASAGVRLKEGSHINRSLLTLGKVVRQLSKGRNGHIPYRDSKLTRILQSSLGGNARTAIICTMSPARSHIEQSRNTLLFATCAKEVVTNAQVNVVMSDKALVKHLQRELERLQSEIKFPAPASCTTHAEALREKDAQIKKLEKQLKELMEERDTVKSQLDCLLKSDCDDHSDGRVAKRWDEHSRSSESFARNASEEAFSVSDTSGVPYQDQDNAVFNGSYVFSDDRDDIVFPVQTVDLPEETKHEKFMSPWHPPSHHSSSDCIESYHMTEAASRTASEVSEEHCREVQCIDIHEHRRSTSHKFDLLLPQDTEFQTPELEISKEAVPQPDEDQELESITNRMEDPTRMCPVEEEQQDEIVDTCESNGTTDNDVKLYTCDSNISFDIQKPYPNGCLTVKRCILSSKDRALSRSKSCRASFMIIPNSWFDDSEYTSQTPPNEILKHTPRRFDKVRRSLYPENDNPSSVDRSEFSGEVSSDEVVKDMSTIDEVAKDMCPSDAEQETLTSDISCLTKLKKTDSDHEDELDEYQDQQSIRDGSTTLRTVKDVGIDSSLSASPSRWPIDFEKMRQEIIQLWHECNAPIVHRTYFFLLFKGDPADNIYMEVEHRRLSFIRRSFSASPAGGELNSAVVSSLKNLRRERDMLYKQMLKKLTNGEKERVYARWGIDLSSKQRRLQLSRLVWTQTDMEHIRESASLVAKLIELLEPAQALKEMFGLNFTLAPRSERRSFGLLGT
What are the official names of this protein?
Kinesin-like protein KIN-7H.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-7 subfamily.
Protein: MED10_XENTR
Sequence: MAEKFDNLEEHLEKFVENIRQLGIIVSDFQPSSQAGLNQKLNFLVTGLQDIDKCRQQLHDITVPLEVFDYIDQGRNPQLYTKECLERALAKNEQVKGKIDTLKKFKSLLIQELSKVFPEDMAKYKAIRGEDHPPS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 10, Mediator complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDH1B_BRAFL
Sequence: MAKFVIAGQADCPYYAKVELLADSLQSKLQDFHVHKIVKTPEEWKPWLQQLCADNGWTHGRSPIIWRELVDRGGKGLLIGGHNDFMEYARSYYGMTSGMLSEMMKNIAAENLAVTQELREEEETIRRQSKPLHVCVINAARSPAYHVLPSLVNGKILREEEIALHLHDSEENLEKLKGLEMEVFDLSFPFLKEISVTTDLPTAFQNAHIAIVLDDFDQGGKEDAIGDMETKVSFYKRVAEAINQTASKDIRVLVAGTGPLNSLVSILIDHTPSIPRQNIAAVAQVKERQAKSLLAKRLTVNSAGVCDVIVWGNVGGTTYTDVSRARVHGYDGAIWGPPSYSCSVSEMVHDNKWLEGEFLEQLQSRSHTIQDSLQHSADLSMAAAISSTLSYWWNGSPEGQLFSLAVCSEGFYNIPEGVVFSFPVMFHKGSWEVVQDIDMNEDMRVMLSSITAQLVEEKDLLLHPTNANHEKLLKVFGVTTDISTPSSVKLDKIMEETEKSSSEDTPEAAAAAVSTGDETVPS
What are the official names of this protein?
Putative malate dehydrogenase 1B.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: CYB_TAMQU
Sequence: MTNIRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGIILLILVLMILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMLFPILHMSKQRSMMFRPLSQCMFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFMIILLILPTISLFENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PSBH_CYACA
Sequence: MALKTRLGELLRPLNSQYGKVAPGWGTTPIMGIFMALFLLFLIIILQIYNSSLILENLDISWTTLGI
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HUTH_METS4
Sequence: MSAVTLTPGRAALAQWRAIRDGAPLRLDPACRPGIARAAETVAAIVARGEPVYGINTGFGKLATVRIAPDDLATLQRNIVLSHAAGVGAPVPAGIVRLMMALKLASLAQGASGVRPETVALLDAMLARGVTPVVPGQGSVGASGDLAPLAHMTAAMIGVGECLDAGGARLPAAAALARADLAPLDLGPKEGLALLNGTQFSTALALAGLFGAEDLLRAGLVTGALSVDAARGSDTPFDPRIHALRRHRGQIDAADALRRLLAGSAIRASHLVGDERVQDPYCLRCQPQVMGAALDLLRQAGATLETEANGVSDNPLVFPETGEALSGGNFHAEPVAFAADMIALALCEIGSLAERRISLLVDPALSSGLPAFLTGRPGLNSGFMIPQVTAAALVSENKQRAYPASVDSIPTSANQEDHVSMAAHGARRLLAMAENAAAVLGIELLAAAQGCDFLAPLRSSEALERVRARLRAAVPRLDEDRYLHPELEAATALVRDGAVVAAAGLDLPGVDGR
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAP_YARLI
Sequence: MAFLPNLVATPMSLASSYSKPVTLGIIGGTGLYKLGALTPVAQIDIDTPWGKPSSPITISETKSGFPVAFLARHGVNHDLTPTDVPSRANIAALKKVGVKAIVAFSAVGSLQEEIAPRDFVVPTQIIDRTKGIRPSSFFEKGFVGHVGFGEPFDVALGKLVAEHADKAFDNSKYKIHTKAKAGKDLTLVCMEGPAFSTRAESQLYRSWNGAVINMSAIPESKLAKEAEIAYQMICMSTDYDAWKEDEEPVTVEQVVSNLTANAESATGVVEALLEPLEKALADKSIGYDLDGSMKFAVSTAPAARDATVAKNLDFLHPGYW
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PAFA_MYCBT
Sequence: MQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDSLVQLVTHDRAGEWVLEDLLVDAEQRLADEGIGGDIYLFKNNTDSAGNSYGCHENYLIVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATYCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMSETTTMLKVGTAALVLEMIESGVAFRDFSLDNPIRAIREVSHDVTGRRPVRLAGGRQASALDIQREYYTRAVEHLQTREPNAQIEQVVDLWGRQLDAVESQDFAKVDTEIDWVIKRKLFQRYQDRYDMELSHPKIAQLDLAYHDIKRGRGIFDLLQRKGLAARVTTDEEIAEAVDQPPQTTRARLRGEFISAAQEAGRDFTVDWVHLKLNDQAQRTVLCKDPFRAVDERVKRLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: Y7239_DICDI
Sequence: MNTATETVQLTKFTQVLCSSGSLGIRIRKRNDKEITNYISEIDLKHFKKKFLNS
What are the official names of this protein?
Putative uncharacterized protein DDB_G0275657.
Protein: MPR1_SCHPO
Sequence: MSVYRDNMYMKYDRNFENRVARRNGQARNASLAKTLHDSGIAERARSPSGSAIPHAYRVMNGSGANDTSLPLTSNPAYVALTSRISSSKSENNQQLAANETAGAPEGTEETVDISNSISDDHANAKNLPAASVKALVGAGVLSDELSVIAYDMSFEDELIQDKQLIDHSVFDQLLEMDDDDEHEFSKSIVWNYFEQAETTIADLQKALEAKDLKKLSSLGHFLKGSSAVLGLTKMRKVCERIQNYGSLRSRDGVMKLPSEEIALDLISKSLSVVNDFYKDARAYLLDFYEKNSST
What is the function of this protein?
Binds to the msc4 response regulator which is part of a multistep phosphorelay system that transmits oxidative stress signals to the spc1 MAPK cascade.
What are the official names of this protein?
Multistep phosphorelay regulator 1.
Protein: YNK4_SCHPO
Sequence: MFRSFGRLFRGSEESPTINDLTSITIYPQCFISTGKEYGSEPKHISVHVRGWVYENPDLNNLGRKDRLMLNLLRRYVGLPPKSKETGTYPEKDDENTNLQVVVDTKAQLNVNVNDGKPNDIELSSTSKTENDPPLSLHTTPDDLQGNGVNVPNPSLSASRSWYQSGYGISGFFNRIMTPSVNSQYISTIGLAKCEEYFEERSLASLQRGLKDEFVLVKIYATDKNFEQKVVAEFNVATNVEGYFIIDEVIPFYTTKNNKFSVEAVLLQSTSEDKVIKAYMSEVPVLDRNGISIISDIDDTVKNTRVIEGPRKVGETTLLAPLNTQTIEGVSDWFRVMTNLNATVHFVSNSPWQLWPTLSKFFTNDNMPYISSIYLRHFNGVLQNIIEPAAARKRSSLLTAIRSLGDRKIVLIGDNGEQDLQIYAEMAACFPERILGIFIRDVMSDFCGVLKKQTTKSNSLPEVVQTKPFATSTPDTPLKEFTTTLKDVDNEQASEFYQLEKEPDTVPSTFILHRYYTYRIFVEDRANKTRKPVVQVEHAASKLENVHILCDYCKHKCSNIMEQDWFVQLARARGVIPLHIPIVIWFNGEEPISFTEDLLKSAFAS
What are the official names of this protein?
Uncharacterized protein C29B5.04c.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: ANP1_YEAST
Sequence: MKYNNRKLSFNPTTVSIAGTLLTVFFLTRLVLSFFSISLFQLVTFQGIFKPYVPDFKNTPSVEFYDLRNYQGNKDGWQQGDRILFCVPLRDASEHLPMFFNHLNTMTYPHNLIDLSFLVSDSSDNTMGVLLSNLQMAQSQQDKSKRFGNIEIYEKDFGQIIGQSFSDRHGFGAQGPRRKLMARARNWLGSVALKPYHSWVYWRDVDVETIPTTIMEDLMHHDKDVIVPNVWRPLPDWLGNIQPYDLNSWKESEGGLQLADSLDEDAVIVEGYPEYATWRPHLAYMRDPNGNPEDEMELDGIGGVSILAKAKVFRTGSHFPAFSFEKHAETEAFGRLSRRMNYNVIGLPHYVIWHIYEPSSDDLKHMAWMAEEEKRKLEEERIREFYNKIWEIGFEDVRDQWNEERDSILKNIDSTLNNKVTVDWSEEGDGSELVDSKGDFVSPNNQQQQQQQQQQQQQQQQQQQQQQLDGNPQGKPLDDNDKNKKKHPKEVPLDFDPDRN
What is the function of this protein?
The M-Pol II complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins.
What are the official names of this protein?
Mannan polymerase II complex ANP1 subunit, M-Pol II subunit ANP1, Aminonitrophenyl propanediol resistance protein.
What is the protein family that this protein belongs to?
Belongs to the ANP1/MMN9/VAN1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Cis-Golgi (PubMed:9430634). Recycles between endoplasmic reticulum and Golgi (PubMed:11095735).
Protein: PURA_FRACC
Sequence: MPALVLIGAQWGDEGKGKATDLLGGAVDYVVRYQGGNNAGHTVVIGAESYALHLIPSGMLRADCVPVIGNGVVIDPGVLLAEMDGLTARGIDVSRLLISANAHLIMPHHRALDRVIERYLGKARIGTTGRGIGPTYGDKVARTGIRVQDLLDPGIFHKKLELVLREKNQVLAKVYNRRRIELDEVVEEYADYAKRLQPHIADTGLILDRALRAGKVVLLEGSQGTLLDVDHGTYPFVTSSNPTAGYAATGAGIGPTRISRVIGIIKAYTTRVGAGPFPTELDDKVGEELRRIGGEFGVTTGRARRTGWFDAVIARYAVRVNGLTDLFLTKLDVLSGFDRVPICVGYDLGGERVDEMPMTQTEFHHAKPIYTDLPGWHEDISDVRSFADLPGAAKDYIRALEEFSGAPVSAVGVGPGRDQTLVINDLV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENH_ECO27
Sequence: MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLYVDLPGHGGSATISVDGFDDVTGLLCKTLVSYNILNFWLVGYSLGGRVAMMAACQELAGLCGVVVEGGHPGLQNAEQRAERQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDDQRRGLVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: EX7S_ECOL5
Sequence: MPKKNEAPASFEKALSELEQIVTHLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_BACC2
Sequence: MRNIQIALTKGRLEKHVIPLFEQIGIDCSELKNKGRKLVFQSKNTNVSFILVKAVDVATYVEHGVADIGIVGKDILMENEKDIYEMLDLGVGICKFCVASIPTYNPKSYRKKRIATKYPHITSTYFHDKGEDVEIIKIEGSVEIAPLLGLADAIVDIVETGKTLQENGLIVFEEMHSISARMIVNKAALKTKKDEIFSIVNMMEQEILSGK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM56_METAR
Sequence: MQDIVILRLGHRPERDARVTTHVGLTARALGAKGMLLTTDDKSVAESIQRVAAAWGGDFWVRAGVSYRSEIRQWKEKGGFVVHLTMYGINLPGCLEQIQEQFKGRGVMIIVGAEKVPGDIYGLADYNVAVGNQPHSEIAALALFMDKLQEGKSLMHEFKGGELKIIPSEHGKSVVKNR
What is the function of this protein?
Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
What are the official names of this protein?
tRNA (cytidine(56)-2'-O)-methyltransferase, tRNA ribose 2'-O-methyltransferase aTrm56.
What is the protein family that this protein belongs to?
Belongs to the aTrm56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLC7A_CAEBR
Sequence: MSNDGDLNIDNLITRLLEVRGCRPGKPVTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYQGMNSGRPAVGGGRPGTTAGKK
What is the function of this protein?
Serine/threonine-protein phosphatase which antagonizes the function of air-2 in the regulation of chromosome cohesion.  Dephosphorylates histone H3 at 'Ser-10'.  Also involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1-alpha, Glc seven-like phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
Protein: RL22_BORPE
Sequence: METTAIIRGVHISAQKTRLVADLIRGKSVAQALNILTFSPKKAAVILKKAVESAIANAEHNDGADIDELKVTTIFVDKAQSMKRFSARAKGRGNRIEKQTCHITVKVGA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: AVLB4_WHEAT
Sequence: MKVFILALLALTATTAIAQLETTCSQGFRQYQQQQQPGQRQLLEQMRPCVAFLQQQCRPLRMPFLQTQVEQLSSCQIVQYQCCQQLAQIPEQIRCHAIHNVVEAIMQQQSQQQRQERQQQAQHKSMRMLLENLSLMCNIYVPIQCQQQQQLGQQQQQQLQEQLTPCATFLQHQCSPVTVPFPQIPVDQPTSCQNVQHQCCRQLSQIPEQFRCQAIHNVAEAIRQQQPQQQWQGMYQPQQPAQLESIRMSLQALRSMCSIYIPVQCPAPTAYNIPMVATYTGGAC
What is the function of this protein?
Seed storage protein.  Might be integrated via inter-chain disulfide bonds within the glutenin polymer (By similarity).
What are the official names of this protein?
Avenin-like b4.
What is the protein family that this protein belongs to?
Belongs to the prolamin family.
Protein: HTPX_YERPE
Sequence: MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGAFVSLLMSKWMALRSVGGEVIERPRNETEYWLLETVRRQSQQVGIAMPQVAIYQAPDINAFATGARRDASLVAVSTGLLQNMSRDEAEAVIAHEISHVANGDMVTMTLIQGVVNTFVIFISRLIAQIAAGFLSGDRDGESNSPGNPMVYFAVSMVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEAGSMMAFCINGKSKTFSELFMSHPPLDKRIEALRSGQYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TDH_SALPC
Sequence: MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDDWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKESLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.