PharMolix/UniProtQA huggingface dataset:
Protein: NRAMA_CAEEL
Sequence: MASSNNDGPIEPEAEPWRITQNDHLEQDLLEEDAESQERVDIPVDDVEKAFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAQAAYKLLWVLLSAHIIGMLLQRMSARLGVVSGKHMAEVAYQFYPRLPRIILWLMIEIAIVCSDMQEVIGTAIAIFLLSKGFVPLYVGVFITILDTFTFLLIDRYGIRKLELIFGFLILTMTVSFGYEFVVVKPPIGEVISGMVVPWCAGCGKGEFMQAISVVGAVIMPHNLYLHSALVKSRRVDRKDRRRVAEANKYFTLESAIALFLSFFINLFVVAVFAHGLYQKTNADVREMCIARHDIPDADIFPNNTEPVEVDIYKGGIYLGCQFGAIAMFIWGIGIFAAGQSSTMTGTYTGQFVMEGFVKIEWPKWKRVLITRAIAITPTLVLTFYSQGVQNLTGMNDFLNCVQMIQLPFALIPIITFTSSRKIMHDFRSSKVFQIFALITSALILSINVYFISDYVFSRLGSEWYIIMVLAPITFAYVLFVLYLALYCLVSCEIIPDTVSIRGFSFNKSYENDAPWLAVDSSAVHDNAGYQ
What is the function of this protein?
Probable divalent metal ion transporter which regulates Mn(2+) uptake.
What are the official names of this protein?
NRAMP-like transporter smf-1, Divalent metal transporter smf-1.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
Protein: FLPA_SULIK
Sequence: MSEVVTVKQTNMENIYECEFNDGSFRLCTRNLVSGFNVYGERLIKYEGVEYREWNAFRSKLAGAILKGLKTNPIRKGTKVLYLGAASGTTISHVSDIIELNGKAYGVEFSPRVVRELLLVAQRRPNIFPLLADARFPQSYKSVVENVDVLYVDIAQPDQTDIAIYNARFFLKVNGYMLLVIKARSIDVTKDPKEIYKAEVEKLENSNFETIQIINLDPYDKDHAIVLSRYKG
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: CWC15_XENTR
Sequence: MTTAARPTFEPARGGRGKGEADLSQLSKQYSSRDLPSHTKIKYRQATQDAPEEVRSRDFRRELEERERVAVREKNRDRPTREHASSVSKKPRLDQIPAANLDADDPLTDEDADDDSDEDSDDDTAALLAELEKIKKERAEEQARKELEQKAEEERIRMENILSGNPLLNLTGPAQSVAAFKVKRRWDDDVVFKNCAKGVDEMKKDKRFVNDTLRSEFHKKFMEKYIK
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.
What are the official names of this protein?
Protein CWC15 homolog.
What is the protein family that this protein belongs to?
Belongs to the CWC15 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y193_HAEIN
Sequence: MIFIFISLFAKIFFNYNDFFTNSHVKIMAKSLLNYQFHQVKQTINTPVLIFIHGLFGDMDNLGVIARAFSEHYSILRIDLRNHGHSFHSEKMNYQLMAEDVIAVIRHLNLSKVILIGHSMGGKTAMKITALCPELVEKLIVIDMSPMPYEGFGHKDVFNGLFAVKNAKPENRQQAKPILKQEINDEDVVQFMLKSFDVNSADCFRFNLTALFNNYANIMDWEKVRVFTPTLFIKGGNSSYIKIENSEKILEQFPNATAFTINGSGHWVHAEKPDFVIRAIKRFLNKN
What are the official names of this protein?
Putative esterase/lipase HI_0193.
What is the protein family that this protein belongs to?
Belongs to the DmpD/TodF/XylF esterase family.
Protein: DUT_FRAP2
Sequence: MNIELKLLNKEIIKEVPEYGTEGSAAVDLRACLSEAEFLSPGECKLIGTGIAINIANPNYAAMILPRSGLGHKKGLVLGNGTGLIDSDYQGELMVSCFNRSQEVIEIEPMMRFAQLVVVPVVQAKFDIVEEFSQRTIRSAGGFGHTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: FFT2_SCHPO
Sequence: MLPYNSNYLSDNGKRKFSDENPQSEVYGSSQTGLPSSYGNPQSYGTPPVQQSSAMYGVNNSMGGGMYNTSENTQFMNTDYSQTSSYASTPMSNAYSRDAPAAINNNFGYSYVGQSSQPVPSYNPLPSYNTASLPNAGIPAAMPGMPSGYPGTVPIPQGGYNAHYSSPYNNGYPIGAVNPTSAIPAQPPAQPVNNVLPSYVRSNSRSSARSTARSAPRSTQRSRSSSANPVTTPPVNNTLLTPPAPPVELPPVTTTSPNAIIRSVQWIRSFVPQAPIHQVINTLAQTKWDETAALSILSQKYLSCDLGIPIQEHKRFKQSPVASNMPTYGSSNRTVQSQKRSIRDKYIQMPNDSTQASLMPSYTRKTSNASKKLTTEEDEFYDSEEEPEAIVHRDTSALERTVLNFINSSTAKELSDTASCPLSHSKLLLEHRPFQTLAEACIIKHPDDVPSKPGRRGRRREKNPMGQKIVNACMETMEGYYAIDNLIAKCEFLGNRISKGMASWGIKLEMSNGELNIVDMESVPTEAADNSDFPKFVTEQPKTLASDVQLKSYQLVGVNWLHLLYQQKLSGILADEMGLGKTCQVVAFFALLLEQGHHGPHLVVVPSSTLENWLRELARFCPSLRVEPYYGSQQERANIREAIEENEIKYDILVTTYQLATNNKEDRSFLKHQNFDVCVYDEGHYLKNRMSERYKHLMNLNANFRLLLTGTPLQNNLKELVSLLAFILPNMFDSDMDDLDVIFKAKPTADADIEQALLSKQRISRAKTMMTPFVLRRRKNQVLNDLPKKTQIIEHCKLSENQLEIYNRYAALQKNQQLRRDDKRNKRSKNDEESDGKSLSAGHVLMQLRKAANHALLFRKFYDDEKLKQMAKDIMQEEQYKNANEQYIYEDMEVMSDFELHRLCRSFPTLQSYTLKDDPWMDSGKIRVLKELLPKMKEEGSRILLFSQFTQMLDILEQVLDTLKISYVRLDGSTQVEVRQDIIDQFHKEEDVTVFLLSTKAGGFGINLACANVVILYDCSYNPFDDLQAEDRAHRVGQVREVTVIRLITDNTIEEYIQKLANTKLALDMSLSSDGKDREEIGERLVQDMLDEENNGNNTKPEITGNESDGEFKVSSSNNSKQTDAEETNTGVPLEGSQPNSVEKTDLADGDEKANIKTEMKSETVEGDNKELRETMKGENVQTDSNAAVPSSKSSTEEPNESVLSGHLDLDTEASPVVSTIEKTTKGDVSVTEEQQSANIDGQLEKPEIEESKKPDVLNQVSLSIEEEKPKNKESEVDNNAAKD
What is the function of this protein?
DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is required for heterochromatin organization.
What are the official names of this protein?
ATP-dependent helicase fft2, Fun thirty-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: END3_MAGOY
Sequence: MAPRIEAQEIETYWNIFSARTNGSKFLTGEQAAPVLKNSGLRDDQLERVWDLADVDNDGNLDFEEFCVAMRVIFDILNGEHADVPSTLPDWLVPESKAHLVQANRALTGKQVQFERVDDDPDSPGLKDGFDWYMSPADKSKYESIYQENRDMRGEVSFGALEDLYESLDVPDTDIRSAWNLINPSAGPTINKDACLAFLHILNYRHEGYRIPRTVPASLRASFERNKIDYQVDKQAASRWATKADDETSTGRKAKFGDQYLTRLGRGSFKTSGTDFSSAQTDSEWEEVRLKKQLAELDAKMASVEADAERRKGGKRDSKPALVKRELEQLLDYKRKQLREIEEGKTKGQGGGSLKGIQDDLQTVREQTDGLASHLRSRQQHLEELRRQIEDEKAGR
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein END3, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: ISCS_SHEDO
Sequence: MKLPIYLDYAATTPVDPRVAEKMMQHMTMDGVFGNPASRSHKYGWQAEEAVDIARNQVADLINADHREIVFTSGATESINLAIKGIAHFYHKKGKHIITSKTEHKAVLDTCRQLEREGYEVTYLEPEANGLIPLARIEDAMRDDTLLVSIMHVNNEIGVIQDVMAIGELCRSKGIIFHMDAAQSAGKLPIDVQQLKVDLISISGHKMYGPKGVGALYVRRKPRIRLESQMHGGGHERGMRSGTLATHQLVGLGEAAAIAKQDMESDNARIRTLRDKLWNGVKHIEETYINGDMEQRFCGSLNVSFNFVEGESLMMALKDLAVSSGSACTSASLEPSYVLRALGLNDEMAHSSIRFSIGRFTTDEDIDHAIKVITQSIDKLREMSPLWEMFKDGIDLDQVQWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BREF4_EUPBR
Sequence: MYHLIPFAAILGMTYALSLAIYRLFLSPLAKFPGPKLAAVTGWVETYYQLFYGEGGQFIFLYKEWHQKYGPIIRINPWEVHISDSCFFEILYSTNRPLKKLPHLAKVFDNELSGFSTVSPELHRIRRKAVSHLFSKGEVLKRGAQIQSAMDRLSERLKLDFLGHGNRVICMNDMWSVYTADLIAEYAFGRHYGFIDQPNFEADFTKALVHLLEPTHLAQQFPWLTDILKALPTSVLEFLHPHMAAFNKFKAANQVRIAKANFAKDLSKGGTMFSAIFNSDLPDEEKSIERAHQEALAFAAAGAETVAATLSVASFHLLHDPKIRRRLDEELATVVPDSRSSDASMPSLEILWQLPYLTGIINEALRLSYGSYARIPRTSDTPIQYDEWTIPPGVVFSMDIAPAHHDERIFPDSYSFKPERWLDNPQAFDGKPLTRYLFSFSRGTRSCLGMQLALAEMYIGIVSFFSRFDAHLFETDLTDITFVRDRFAPRPRIGSRGVRVNRLTTRKF
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of brefeldin A (BFA), a protein transport inhibitor that shows antiviral, antifungal, and antitumor properties (PubMed:24845309).  The proposed biosynthesis of BFA involves formation of an acyclic polyketide chain that is differentially tailored throughout the backbone (PubMed:24845309).  The highly reducing polyketide synthase Bref-PKS is proposed to synthesize the precisely reduced octaketide precursor, which could then be directly offloaded by the thiohydrolase enzyme Bref-TH followed by a cytochrome P450 monooxygenase-mediated formation of the cyclopentane ring and macrocyclization to afford 7-deoxy BFA.  Alternatively, the first ring annulation can also occur on the ACP-tethered intermediate before the thiohydrolase release and lactonization (PubMed:24845309).  The C7-hydroxylation by another cytochrome P450 monooxygenase is believed to be the final step in the process to obtain the final structure of BFA (PubMed:24845309).  In addition to the HRPKS Bref-PKS and the thiohydrolase Bref-TH, the brefeldin A biosynthesis cluster contains 4 cytochrome p450 monooxygenases (called orf3 to orf6), as well a the probable cluster-specific transcription regulator orf8 (PubMed:24845309).
What are the official names of this protein?
Cytochrome P450 monooxygenase orf4, Brefeldin A biosynthesis cluster protein orf4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: DNAT_CITK8
Sequence: MSSRILTPDVIGIDALLHDHNAVLAKSASGAVAVFANNAPAFYAVTPARLAELLALEEKLSRPGSDVTLDAQLYEDSQAAPVAVPLGKFAMYADWQPDANFQRQAALWGVALREPVTAEELASFVAYWQAEGKIFHHIQWQQKLARSVQISRASNGGMPKRDVNNVSEPDDHIPPGFRG
What is the function of this protein?
This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response.  It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.
What are the official names of this protein?
Primosomal protein 1, Primosomal protein I.
What is the protein family that this protein belongs to?
Belongs to the DnaT family.
Protein: FAR8_NAMOO
Sequence: ARTDNFVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-8, FMRFa-8.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CK054_MOUSE
Sequence: MACSEFSFHMPSLEELAEVLQKGLTDNFADVQVSVVDCPDLTKEPFTFPVRGICGQTRIAEVGGVPYLLPLVNKKKVYDLNEIAKVIKLPGAFILGAGAGPFQTLGFNSEFMPIVQTASEHNQPVNGSYFAHKNPADGACLLEKYSQKYHDFGCALLANLFASEGQPGKVIEVQAKRRTGELNFVSCMRQTLEEHYGDKPVGMGGTFIVQKGKVKAHIMPAEFSSCPLNSDEAVNKWLHFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD
What is the function of this protein?
Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
What are the official names of this protein?
Ester hydrolase C11orf54 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL24_PSEPW
Sequence: MQKIRRDDEIIVIAGKDKGKRGKVLKVLADDRLVIGGVNLVKRHTKPNPMAGVQGGIVEKEAPLHASNVAIFNGETNKADRVGFKVEDGKKIRVFKSTQKAVDA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: GATL3_ARATH
Sequence: MSSLRLRLCLLLLLPITISCVTVTLTDLPAFREAPAFRNGRECSKTTWIPSDHEHNPSIIHIAMTLDAIYLRGSVAGVFSVLQHASCPENIVFHFIATHRRSADLRRIISSTFPYLTYHIYHFDPNLVRSKISSSIRRALDQPLNYARIYLADLLPIAVRRVIYFDSDLVVVDDVAKLWRIDLRRHVVGAPEYCHANFTNYFTSRFWSSQGYKSALKDRKPCYFNTGVMVIDLGKWRERRVTVKLETWMRIQKRHRIYELGSLPPFLLVFAGDVEPVEHRWNQHGLGGDNLEGLCRNLHPGPVSLLHWSGKGKPWLRLDSRRPCPLDSLWAPYDLFRYSPLISDS
What is the function of this protein?
May be involved in pectin and/or xylans biosynthesis in cell walls.
What are the official names of this protein?
Probable galacturonosyltransferase-like 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RUVC_VIBCM
Sequence: MSVILGIDPGSRVTGYGVIRQQGRHLIYLGSGCIRTSDLELPLRLKQIYAGVSEIITQFQPDAFAIEQVFMAKNADSALKLGQARGSAIVAAVNAELPVYEYAARLIKQAVVGTGAADKSQVQHMVQQMLKLPGKPQADAADALGVAICHANTNKTLIALAGQATSARRGRYR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: REC14_SCHPO
Sequence: MRKEYLVSHIEENAHQADIYSLNVVAGNLWSASGDSKIKKWSIGDAEHSLVEEIDTPHKLGVHHLATSLDENVVVSCGFGQDVYVWNPETNEFRDLGNNAQHPSECWSSCISPDGQTIAFTSVDGRIAVWDNPSDCKISELDTKGKFGLCIDYSPNGRFIVSGHQTGQLFLISTETGRLFHVLSGHTSPVRSVAFSPGSTLLAAAGDSKMITIYDVLSGDQVGQLRGHAAWIFAVAFNPVGDLLLSADVEGKIKIWDIDTMECISTQSETDGAIWAVAWYKNGFIVAGADKSIRWYRAAATE
What is the function of this protein?
Required for formation of the rec12-mediated double-strand breaks (DSBs) that initiate meiotic recombination.
What are the official names of this protein?
Meiotic recombination protein rec14.
Protein: ANFC4_ORYLA
Sequence: MNLSYLVACGLLVTFLSDKMDAQPLTPAQQKSLRSLLGEELAEFLESGENENRLDDVRSRMRLLRDLRVDTRARGMWARLLNDQPASRRHKSGSKKGGSTSRSGCFGHKMDRIGTISGMGC
What is the function of this protein?
Exhibits natriuretic and vasodepressant activity.  Has cGMP-stimulating activity.  May help to regulate body fluid homeostasis in a variety of aquatic environments.
What are the official names of this protein?
C-type natriuretic peptide 4.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLUD_PSEAE
Sequence: MSDMIQRAAEVPFELGGQRLDQIAAQLFPEHSRSRLAGWIKDGRLTVDGAVLRPRDIVHSGAQLVLEAEQEAQGEWLAQDIELEIVYEDEHILVIDKPAGLVVHPAAGHQDGTLLNALLYHVPDIANVPRAGIVHRLDKDTTGLMVVAKTLEAHTKLVAQLQARSVSRIYEAIVIGVITSGGTIDAPIGRHGVQRQKMAVVDAGKVAVSHYRVLERFRAHTHTRVKLETGRTHQIRVHMSHIGYPLVGDPVYGGRFRIPPVASQTLVQTLREFPRQALHARFLELDHPATGVRMKWESPLPEDFLWLLSLLRQDREAFVG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase D, 23S rRNA pseudouridine(1911/1915/1917) synthase, rRNA pseudouridylate synthase D, rRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: MURA1_STAAR
Sequence: MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATKTLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSIHLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAGTLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELEYQEDGIRVRAEGDLQPVDIKTLPHPGFPTDMQSQMMALLLTANGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDRGYVDLHGKLKQLGADIERIND
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEAH_PHAVU
Sequence: XXXGLXIVDAFVQPNLILQGDAKVEDNGXL
What is the function of this protein?
Lectin and alpha-amylase inhibitor.  Acts as a defensive protein against insects (By similarity).
What are the official names of this protein?
Putative alpha-amylase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: MXRA8_MOUSE
Sequence: MELLSRVLLWKLLLLQSSAVLSSGPSGTAAASSSLVSESVVSLAAGTQAVLRCQSPRMVWTQDRLHDRQRVVHWDLSGGPGSQRRRLVDMYSAGEQRVYEPRDRDRLLLSPSAFHDGNFSLLIRAVDRGDEGVYTCNLHHHYCHLDESLAVRLEVTEDPLLSRAYWDGEKEVLVVAHGAPALMTCINRAHVWTDRHLEEAQQVVHWDRQLPGVSHDRADRLLDLYASGERRAYGPPFLRDRVSVNTNAFARGDFSLRIDELERADEGIYSCHLHHHYCGLHERRVFHLQVTEPAFEPPARASPGNGSGHSSAPSPDPTLTRGHSIINVIVPEDHTHFFQQLGYVLATLLLFILLLITVVLATRYRHSGGCKTSDKKAGKSKGKDVNMVEFAVATRDQAPYRTEDIQLDYKNNILKERAELAHSPLPAKDVDLDKEFRKEYCK
What is the function of this protein?
Transmembrane protein which can modulate activity of various signaling pathways, probably via binding to integrin ITGAV:ITGB3 (PubMed:18366072, PubMed:22492581, PubMed:29702220).  Mediates heterophilic cell-cell interactions in vitro (PubMed:18366072).  Inhibits osteoclastogenesis downstream of TNFSF11/RANKL and CSF1, where it may function by attenuating signaling via integrin ITGB3 and MAP kinase p38 (PubMed:22492581).  Plays a role in cartilage formation where it promotes proliferation and maturation of growth plate chondrocytes (PubMed:29702220).  Stimulates formation of primary cilia in chondrocytes (PubMed:29702220).  Enhances expression of genes involved in the hedgehog signaling pathway in chondrocytes, including the hedgehog signaling molecule IHH; may also promote signaling via the PTHLH/PTHrP pathway (PubMed:29702220).  Plays a role in angiogenesis where it suppresses migration of endothelial cells and also promotes their apoptosis (By similarity).  Inhibits VEGF-induced activation of AKT and p38 MAP kinase in endothelial cells (By similarity).  Also inhibits VTN (vitronectin)-mediated integrin ITGAV:ITGB3 signaling and activation of PTK2/FAK (By similarity).  May play a role in the maturation and maintenance of the blood-brain barrier (PubMed:14603461).
What are the official names of this protein?
Matrix remodeling-associated protein 8, Adipocyte-specific protein 3, Dual Ig domain-containing cell adhesion molecule, DICAM, Limitrin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Cytoplasm. Cell projection, cilium membrane. Nucleus. Note=Primarily localizes to the cell membrane (PubMed:18366072). Detected in the cilium of primary chondrocytes (PubMed:29702220). Highly expressed at areas of cell-cell contact and may localize to tight junctions (PubMed:18366072). Also found in the nucleus where it is detected in the soluble (as opposed to chromatin-bound) fraction (PubMed:18366072).
Protein: RFL3S_HUMAN
Sequence: MQTDTSNLSARSCRFCVMSPLRTLLRSSEMRRKLLAVSASKVISTVKRKTSCSASGQKPTPCLSSTSKAQISPDFSFFNSVSSSKIKTFHEETSLFQIFIGMLCGNT
What are the official names of this protein?
Putative protein RFPL3S, RFPL3 antisense RNA 1, RFPL3 antisense gene protein 1, Ret finger protein-like 3 antisense gene protein.
Protein: EXB6L_ARATH
Sequence: MIGELDFPFLGAGSTGGACGFAVANPPLYGMVSAGGPSVFNNGIGCGTCFQILCNGHPACSRRPITVTITDECPGGPCASEPAHFDLSGKAMGALARPGQGDRLRSAGVLRVYYRRVECLYRRTNIAFRMDPGANPYYISFVVEYENGDGDLAYIEIQPADGEFIPMQEMRSAVWKISSGSPLTGPFNIRLTSAESHKVVLAYNVIPANWKPNETYRSVVNFK
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.
What are the official names of this protein?
Expansin-B6, At-EXPB6, AtEXPB6, Beta-expansin-6.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin B subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: HAD9_PSEPU
Sequence: MQPIEGIVFDLYGTLYDVHSVVQACESAYPGQGEAISRLWRQKQLEYTWLSSLMGRYASFEQRTEEALRYTCKHLGLATDETTLRQLGQAYLHLAPHPDTTAALRRLKASGLPMAIASNGSHHSIEQVVSHSDMGWAFDHLISVETVKVFKPDNRVYSLAEQTMAIPRDRLLFVSSNSWDATGARHFGFPVCWVNRQGAVFDELGATPTREVRDLGEMSDWLLD
What is the function of this protein?
Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids (By similarity).  Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 (By similarity).  Active with 2-halogenated carboxylic acids and converts only the S-isomer (or L-isomer) of 2-chloropropionic acid with inversion of configuration to produce R-lactate (or D-isomer) (By similarity).
What are the official names of this protein?
(S)-2-haloacid dehalogenase H-109, 2-haloalkanoic acid dehalogenase H-109, Halocarboxylic acid halidohydrolase H-109, L-2-haloacid dehalogenase H-109.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
Protein: MOC2B_DROGR
Sequence: MDHIQLVNSQIDINHIHNLLIDESCGASSVFVGTTRDNFDGKKVISLEYESYEKMALKEMSKICSQLRARWPDLKHIAIYHRLGTVPVKEASVVIATSAPHRAAALESVTFAVEQLKSRVPIWKKEIYENDTIGEWKENMECPWPQYSKASLRTFDFSSCKIKQTIENIPDKLVQIRVNDSDLNKRVKCFLKRKRDEINLHNINDFKQQSSQIPCEETTTFSCARTQSFLVKQQQSSGHLKVRRANNCCGPQVRPNYSLQLNKLMTPQSDCDDLIEYKLGNSRLRNIEAYMCVSPDDDNILNRIKNIEDRILLIESTSPEYKHFVQFGTDSEKTCLKKPKKEVYLTDRINEFLTKIKREIEQ
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated Mocs2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_PROMA
Sequence: MNINYSELSSSRSLSVIAPAKINLHLEVLGFRKDGFHELAMLMQSINLFDEIDFLKTDNGEITLTSDDPNLSTGDDNLILKAAQLIQTCSSDKNVGAEIHLKKNIPIGAGLAGGSSDAAATLVGLNSLWGIGSSEKQLEKLGSELGSDVPFCLRGGTQFCFGRGESLEMIPEIKQSMAVVLVKDPLVEVSTPWAYSKFKEIYGNDYLKMEEDFEKRRQSLRDASWLNPLNCTNPPPLQNDLQKVIEPITPAVRNALEFLSSLEGVLSLAMSGSGPSCFGIFADLNGAQIALEENRNKLKLSGLDAWCCAFKSSGVSLRL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.