PharMolix/UniProtQA huggingface dataset:
Protein: HNFAB_XENLA
Sequence: MASQLSYLQQELLRALLESGVTKEALKKALADGDNYAYPNVPLDDIRNLDEGDNCVQLPNGLGEPQMSEDESSDDGGDFTPPIMKELERLSPEEAAHQKAVVERLLQEDPWHVAKLVKSYLQQHNIPQREVVDTTGLNQSHLSQHLNKGTPMKTQKRAALYAWYVGKQREIARQFTHAGHSMITDDMSCDDVPNKKMRRNRFKWGPASQQILFQAYERQKNPSKEEREALVEECNRAECLQRGVSPSQAQGLGSNLVTEVRVYNWFANSGKEEAFRHKLAMDTYNGQQSSAQPLSTHDLPHGKTPRYTQDSSTDRSAAMANSQSTLSPSALEPSHILMNSDSKMVPVSGGSLPPVSTLTALHSLDHSQHTLGQTQNLIMASLPSVMTIGTDSALGPAFSNPGSSTLVIGLASQTQSVPVINSVGSSLTTLQSVQFSQQLHPSHQQPIVQQVQSHMAQSPFMATMAQLQSPHALYSHKPEVAQYTSAGFFPQTMVITDTSNLGTLTSLTPSKQVVSHHPTAHGDSPGSQLHNQDSSILHLHPSHRLSPIPTVSSASLIHYHNSSSPENHSHLLSPSHNTIDSFISTQMASSSQ
What is the function of this protein?
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreas and liver (By similarity).  Binds to the hepatocyte specific promoter element HP1.  Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.
What are the official names of this protein?
Hepatocyte nuclear factor 1-alpha-B, HNF-1-alpha-B, HNF-1A-B, LFB1, Transcription factor 1-B, TCF-1-B, XlFB1b.
What is the protein family that this protein belongs to?
Belongs to the HNF1 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OTSA_CITK8
Sequence: MGRLVVVSNRIAPPDNKGGAGGLAVGVLGALKAAGGLWFGWSGETGNEDKPLKKVTRGNMTWASFNLSEQDYEEYYCQFSNAVLWPAFHYRLDLVQFQRPAWEGYSRVNALLADKLLPLLKDDDIIWVHDYHLLPFASELRKRGVNNRIGFFLHIPFPTPEIFNALPPHDTLLEQLCDFDLLGFQTENDRLAFLDSLSSQTRVTTRGSKSHSAWGKSFRTEVYPIGIEPDEIAQQASGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFQAYEALLEKYPQHHGKIRYTQIAPTSRGEVQAYQDIRHQLETEAGRINGKYGQLGWTPLYYLNQHFDRKLLMKVFRYSDVGLVTPLRDGMNLVAKEFVAAQDPANPGVLVLSQFAGAANELTSALIVNPYDRDDVAVALHRALTMPLAERISRHAEMLETIIKNDINHWQQRFIRDLKDVAPRSAETLHRNKVATFPKLA
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose.  Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Acts with retention of the anomeric configuration of the UDP-sugar donor.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: POLN_HEVMG
Sequence: MEAQQFIKAPGITTAIEQAALAAANSALANAVVVRPFLSRVQTEILINLMQPRQLVFRPEVLWNHPIQRVIHNELEQYCRARAGRCLEVGAHPRSINDNPNVLHRCFLRPVGRDVQRWYSAPTRGPAANCRRSALRGLPPVDRTYCFDGFSRCAFAAETGVALYSLHDLWPADVAEAMARHGMTRLYAALHLPPEVLLPPGTYHTTSYLLIHDGDRAVVTYEGDTSAGYNHDVSILRAWIRTTKIVGDHPLVIERVRAIGCHFVLLLTAAPEPSPMPYVPYPRSTEVYVRSIFGPGGSPSLFPSACSTKSTFHAVPVHIWDRLMLFGATLDDQAFCCSRLMTYLRGISYKVTVGALVANEGWNASEDALTAVITAAYLTICHQRYLRTQAISKGMRRLEVEHAQKFITRLYSWLFEKSGRDYIPGRQLQFYAQCRRWLSAGFHLDPRVLVFDESVPCRCRTFLKKVAGKFCCFMRWLGQECTCFLEPAEGLVGDYGHDNEAYEGSEVDPAEPAHLDVSGTYAVHGRQLEALYRALNVPHDIAARASRLTATVELTASPDRLECRTVLGNKTFRTTVVDGAHLEANGPEQYVLSFDASRQSMGAGSHSLTYELTPAGLQVRISSNGLDCTATFPPGGAPSAAPGEVAAFCSALYRYNRFTQRHSLTGGLWLHPEGLLGIFPPFSPGHIWESANPFCGEGTLYTRTWSTSGFSSDFSPPEAAAPVLAAAPGLPHPTPPVSDIWVLPPPSEESQVDAASVPPAPEPAGLPSSIVLTLPPPLPPVRKPPTPPPSRTRRLLYTYPDGAKVYAGSLFESDCNWLVNASNPGHRPGGGLCHAFYQRFPEAFYPTEFIMREGLAAYTLTPRPIIHAVAPDYRVEQNPKRLEAAYRETCSRRGTAAYPLLGSGIYQVPVSLSFDAWERNHRPGDELYLTEPAAAWFEANKPAQPALTITEDTARTANLALEIDAATDVGRACAGCTISPGIVHYQFTAGVPGSGKSRSIQQGDVDVVVVPTRELRNSWRRRGFAAFTPHTAARVTIGRRVVIDEAPSLPPHLLLLHMQRASSVHLLGDPNQIPAIDFEHAGLVPAIRPELAPTSWWHVTHRCPADVCELIRGAYPKIQTTSRVLRSLFWNEPAIGQKLVFTQAAKAANPGAITVHEAQGATFTETTIIATADARGLIQSSRAHAIVALTRHTEKCVILDAPGLLREVGISDVIVNNFFLAGGEVGHHRPSVIPRGNPDQNLGTLQAFPPSCQISAYHQLAEELGHRPAPVAAVLPPCPELEQGLLYMPQELTVSDSVLVFELTDIVHCRMAAPSQRKAVLSTLVGRYGRRTKLYEAAHSDVRESLARFIPTIGPVQATTCELYELVEAMVEKGQDGSAVLELDLCNRDVSRITFFQKDCNKFTTGETIAHGKVGQGISAWSKTFCALFGPWFRAIEKEILALLPPNIFYGDAYEESVFAAAVSGAGSCMVFENDFSEFDSTQNNFSLGLECVVMEECGMPQWLIRLYHLVRSAWILQAPKESLKGFWKKHSGEPGTLLWNTVWNMAIIAHCYEFRDFRVAAFKGDDSVVLCSDYRQSRNAAALIAGCGLKLKVDYRPIGLYAGVVVAPGLGTLPDVVRFAGRLSEKNWGPGPERAEQLRLAVCDFLRGLTNVAQVCVDVVSRVYGVSPGLVHNLIGMLQTIADGKAHFTETIKPVLDLTNSIIQRVE
What is the function of this protein?
RNA-directed RNA polymerase: Plays an essential role in the virus replication (By similarity).  Binds to the 3'-end of the genomic RNA to initiate viral replication (By similarity).
What are the official names of this protein?
Non-structural polyprotein pORF1.
What is the protein family that this protein belongs to?
Belongs to the hepevirus non-structural polyprotein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RGMG3_AGRFC
Sequence: MTATASALRMRGISKIFPGVKALSNVNFTVEYGRIHAVVGENGAGKSTLMKILSGSYAPTTGTTEIAGVEVQMRRPADAQKLGIRMVHQELNLVPDLTVAENIYLGRMPHRRFLVDRQAMLRKAAAVLKELEAAIDPKARLGDLPISQQQLVEIAKSYSADPRIIVLDEPTSSLSEHETTALFSILRKMKSQGIAIIYISHRLKEVLDIADDVTILRDGSMIDTRPAAGITAAEMIRLMVGREVANVFPKTPSKIGPVAFKVTGLSDGEKFHDVGFDVRSGEILGLTGLVGAGRTEVAQAIFGLAPLATGRIEINGKAVTIGSPAAAVKAGVAYVPEDRKGDGIVPSMSVRENISLPVLRRLSRLGRIGMSRDRGLAAKYTRDFSIVPPDPERRINLLSGGNQQKAIISRWLAAGPKVLILDEPTRGVDVGAKAEIHRIIGELVAGGMAVVMISSELPEVMGVCDRVVVMRDGRASSPIARGDLTEERIMALATGEEPA
What is the function of this protein?
Part of an ABC transporter complex involved in carbohydrate import.  Could be involved in ribose, galactose and/or methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Putative ribose/galactose/methyl galactoside import ATP-binding protein 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: THG1_RAT
Sequence: MWAFSTARIGSPLAATSVTLRRCLRLGVAMAKSKFEYVRDFEVDDTCLPHCWVVVRLDGRNFHRFAEKHNFAKPNDSRALHLMTKCAQTVMQELEDIVIAYGQSDEYSFVFRKRSNWFKRRASKFMTLVASQFASSYVFYWRDYFEDQPLLYPPGFDGRVVLYPSNQTLKDYLSWRQADCHINNLYNTVFWALIQQSGLTPVQAQQRLKGTLTADKNEILFSEFHINYNNEPHMYRKGTVLVWQKVNEVRTQEIRLPAEMEGEKMAVTRTRTKLVALNCDLIGDAFWKEHPEILEGED
What is the function of this protein?
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.  This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.  Also functions as a guanyl-nucleotide exchange factor/GEF for the MFN1 and MFN2 mitofusins thereby regulating mitochondrial fusion.  By regulating both mitochondrial dynamics and bioenergetic function, it contributes to cell survival following oxidative stress.
What are the official names of this protein?
Probable tRNA(His) guanylyltransferase, tRNA-histidine guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(His) guanylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: RS5_LACLA
Sequence: MAENRRNDREQSEFEERVVSINRVTKVVKGGRRLRFAALVVVGDRNGRVGFGTGKAQEVPEAIRKAIEAAKKNLITVPMVGTTLPHEALGVFGGGKILLKPAVEGAGVAAGGAVRAVLELAGVADVTSKSLGSNTPINVVRATVDGLNQLKRAEEVAALRGKSVSDFA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: KBP_CHICK
Sequence: MAAAGGGWAAACEKFRSARTLSAVESRKDPETEPYRSKYSARALLQEVKQQLSAAEDCGEARLLAVRRAVLEYELGVNHTDTEELSAGEEHLQRCTQLLEPHRLSRDCVSLYIQAQNNLGILWSERDEIKTAQTYLESAEALYNQYMKEDGNPPLDPSEHFMAEEEKLTDQERSKRFEKAYTHTLYYLAQVYQHLEMIEKAAQYCHTTLKRQLEYCGYYPVEWALNAATLSQYYLSKQCFMESRHCLAAASVIFSQAGQVPSTEDNETEQDQQDLRQRKAEIARCWIKYCLNLLQSARKLLEDNIGELDPDRQLELKAQRKKEEDEKENGRKKAVLFGTSDICDSVLAMEEKVSSVYPLDFQEAREIFLVGQNYVQEAKEFFQVDGYVTDHIEIVQDHSALFKVLAFFEEDYERRCKMHKRRIDMLEPIYADLNPQYYLLISRQLQFELADTYYEMMDLKVAIGNRLEELDSHTIKKINSLAQLAIKYYELFLDSLRNPDKVFPEELEEDVLRPAMVAKFHIARLYGKLITSDSKKQLENMQTSLEYYTFLVDYCEKHPDAVRAVETELELSKEMVGLLPTRMERLRAKLCPFI
What is the function of this protein?
Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.
What are the official names of this protein?
KIF-binding protein, KIF1-binding protein.
What is the protein family that this protein belongs to?
Belongs to the KIF-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: KTI1_SELUD
Sequence: LVLDVDGNPLEVGSEYYIGRAVGFYVVERFSEVDRGDPLSSDVQIDSGLSAYCRSDGFWGVPPSSFRIEKTEGFPNAYKIAYSPPTTSSQQQRYPDLHSGLNLVGLTDDSARVVL
What is the function of this protein?
Exhibits Kunitz trypsin protease inhibitor activity.
What are the official names of this protein?
Kunitz-type trypsin inhibitor 1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: UBC_ASFM2
Sequence: MVSSFLLAEYKNLIVNPSEHFKISVNEDNLTEWDVILKGPPDTLYEGGLFKAKIVFPPKYPYEPPRLTFTSEMWHPNIYSDGKLCISILHGDNAEEQGMTWSPAQKIDTVLLSVISLLNEPNPDSPANVDAAKSYRKYLYKEDLESYPMEVKKTVKKSLDECSAEDIEYFKNVPVNVLPVPSDDYEDEEMEDGTYILTYDDEDEEEDEEMDDE
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (By similarity).  Performs the second step in the ubiquitination reaction that targets specifically a protein for degradation via the proteasome (By similarity).  By controlling the ubiquitination status of specific host proteins, the virus may target them to degradation and thereby optimize the viral replication (By similarity).  May be implicated in the shutoff of protein synthesis through its interactions with components of the host translation machinery (By similarity).  Blocks p65 nuclear translocation upon cytokine stimulation, thereby impairing NF-kappa-B signaling (By similarity).  Inhibits type I IFN production and 'Lys-63'-linked polyubiquitination of host TBK1 through binding to host RNF138.  This binding enhances the interaction between RNF138 and RNF128 and promotes RNF138-mediated degradation of RNF128.  Also inhibits the activation of AP-1 transcription factor (By similarity).  Monoubiquitinates the viral protein P15/PIG1 in vitro (PubMed:7853518).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2, E2 ubiquitin-conjugating enzyme, UBCv1, Ubiquitin carrier protein, Ubiquitin-protein ligase, pI215L.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Virion. Note=Accumulates in the perinuclear cytoplasmic viral factories. Faintly detected in the nucleus.
Protein: RLMN_MOOTA
Sequence: MTTRIDLRGLLPQELEELAVRLGEAPYRGRQIFRWLHARRAKGIEVMSDLPRAFRERLALVAELPPVRVLNRLVAADGLTRKLLLGLGDGNSIECVLMIYKDGRRRNTACLSSQVGCAMGCSFCATGQGGLQRNLTASEIILQALALGAELAEGEGGNRISNIVFMGMGEPLNNYEAVMKGVRIFEDPSGWGISHRRITLSTCGIVPGIERLAREKPPLELAVSLHAVTNELRDKLMPINRRYPLEELIPACRRYAEITGRRVTFEYALIAGVNDRREDARGLSRLLRDMLAFVNIIPLNPVAGSGFKGVPPAAARAFVALLQEAGLEAAIRDSRGQDIAAACGQLRFASREVL
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP2_MEDTR
Sequence: MKVSTIESGEISKGASSPRKGMKRGLSIMDFILRIFAAMSTLGSALSMGTAKQTMPFATRFVRFKVSFHDLPTFLFFVTANSIVCGYLALSLVLSFFHIVRTISVKSRILLVFLDTVMFGLLTSGASAAAAIVYVAHYGNPSANWFPFCQQYNSFCGRISGSLVGSFIAVVIFMILILMSGISISKSKH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 2, MtCASP2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: PKG1_ADE02
Sequence: METRGRRPAALQHQQDQPQAHPGQRAARSAPLHRDPDYADEDPAPVERHDPGPSGRAPTTAVQRKPPQPAKRGDMLDRDAVEHVTELWDRLELLGQTLKSMPTADGLKPLKNFASLQELLSLGGERLLAHLVRENMQVRDMLNEVAPLLRDDGSCSSLNYQLQPVIGVIYGPTGCGKSQLLRNLLSSQLISPTPETVFFIAPQVDMIPPSELKAWEMQICEGNYAPGPDGTIIPQSGTLRPRFVKMAYDDLILEHNYDVSDPRNIFAQAAARGPIAIIMDECMENLGGHKGVSKFFHAFPSKLHDKFPKCTGYTVLVVLHNMNPRRDMAGNIANLKIQSKMHLISPRMHPSQLNRFVNTYTKGLPLAISLLLKDIFRHHAQRSCYDWIIYNTTPQHEALQWCYLHPRDGLMPMYLNIQSHLYHVLEKIHRTLNDRDRWSRAYRARKTPK
What is the function of this protein?
Component of the packaging machinery which encapsidates the viral DNA into preformed capsids and transcriptional activator of the viral major late promoter (MLP).  Binds, along with packaging proteins 2 and 3, to the specific packaging sequence on the left end of viral genomic DNA and displays ATPase activity thereby providing the power stroke of the packaging machinery.  The activity of packaging protein IVa2 is stimulated by protein 33K which acts as a terminase.  May be the protein that pumps DNA into the capsid powered by ATP hydrolysis.  Specifically binds to the 5'-CG-3' nucleotides of the repeats making up the packaging sequence.  Component of the DEF-A and DEF-B transcription factors that bind downstream elements of the major late promoter (MLP), and stimulate transcription from the MLP after initiation of viral DNA replication.  DEF-A is a heterodimer packaging proteins 1 and 2 and DEF-B is a homodimer of packaging protein 1.
What are the official names of this protein?
Packaging protein 1, Packaging protein IVa2.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae packaging protein 1 family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleoplasm. Host nucleus, host nucleolus. Note=Located at a unique vertex of the capsid. Present in about 6-8 copies per virion.
Protein: QUEA_AGRFC
Sequence: MRVDLFDFDLPEENIALRPANPRDSARLLVVDPNENRMEDHRVFDLPSFLRPGDALVFNDTRVIPAQLEGVRLREGAPETAVSATLHMRADQSRWKAFARPGKRIKEGDRIRFGYDRDTVNSSSGACGLAHLEATVEEKGEEGEITLLFDISGPVLDEAIASVGHIPLPPYIAAKRPEDQQDQTDYQTIYAREKGAVAAPTAGLHFTPDLFEALDSAGIERHFVTLHVGAGTFLPVKSDDTDDHKMHFEIGYVSQETADRLNAVKARGGRIVCVGTTSLRLIESAATEDGTIHPWSDATGIFITPGYRFRAVDMLMTNFHLPKSTLFMLVSAFCGLETMRDAYRHAIETGYRFYSYGDSSLLFRKN
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_STRPM
Sequence: MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHMIYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKLQKAKETTGLHEAVLTGKAMVKGQQIALAIMDSHFIMASMGTVVGEKITRLFELAIEENLPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFAMGGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDKIAHLVAFHGGGQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCB_ECO27
Sequence: MFRRLLIATVVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQTDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWIACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDALLYSVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGGLIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVFTPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAKHS
What is the function of this protein?
Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
Voltage-gated ClC-type chloride channel ClcB.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOH_BURCM
Sequence: MSLFDTINAGGAQLLGIAWPTVWAIVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPAGLLQPIADVLKLLLKEVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFVSGIAETNRHPFDVVEGESEIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGVFWLVLKVFALLSVFIWVRATFPRYRYDQIMRLGWKVFLPVTVIWVVVVGFWMMSPLNIWVK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LSHB_HUMAN
Sequence: MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPTMMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFL
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin subunit beta, Lutropin beta chain, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: BGAL_ARTSB
Sequence: MSSSYITDQGPGSGLRVPARSWLNSDAPSLSLNGDWRFRLLPTAPGTPGAGSVLATGETVEAVASESFDDSSWDTLAVPSHWVLAEDGKYGRPIYTNVQYPFPIDPPFVPDANPTGDYRRTFDVPDSWFESTTAALTLRFDGVESRYKVWVNGVEIGVGSGSRLAQEFDVSEALRPGKNLLVVRVHQWSAASYLEDQDQWWLPGIFRDVKLQARPVGGLTDVWLRTDWSGSGTITPEITADPAAFPVTLRVPELGLEVIWDSPADVAPVSIDAVEPWSAEVPRLYDASVSSAAESISLRLGFRTVKIVGDQFLVNGRKVIFHGVNRHETNADRGRVFDEASAREDLALMKRFNVNAIRTSHYPPHPRFLDLADELGFWVILECDLETHGFHALKWVGNPSDDPAWRDALVDRMERTVERDKNHASIVMWSLGNESGTGANLAAMAAWTHARDLSRPVHYEGDYTGAYTDVYSRMYSSIPETDSIGRNDSHALLLGCNAIESARQRTRPFILCEYVHAMGNGPGAIDQYEDLVDKYPRLHGGFVWEWRDHGIRTRTADGTEFFAYGGDFDEVIHDGNFVMDGMILSDSTPTPGLFEYKQIVSPIRLALTLNAEGNAGLTVANLRHTSDASDVVLRWRVEHNGTRVDAGELTTDGANGPLQAGDSLTLTLPTIVAAAEGETWLSVEAVLREATAWAPAGHPLSETQLDLSPAQPPLRVPRPASPIAGAAPVELGPATFDAGSLVTLAGLPVAGPRLELWRAPTDNDKGQGFGAYGPEDPWINSGRGVPAPSSAVVWQQAGLDRLTRRVEDVAALPQGLRVRSRYAAANSEHDVAVEENWQLSGDELWLRIDIAPSAGWDLVFPRIGVRLDLPSEVDGASWFGAGPRESYPDSLHSAVVGTHGGSLEELNVNYARPQETGHHSDVRWVELSRDGAPWLRIEADPDALGRRPGFSLAKNTAQEVALAPHPHELPESQHSYLYLDAAQHGLGSRACGPDVWPDFALRPEARTLVLRIRAA
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: YP41_SCHPO
Sequence: MSNPESLKKQVEPPGYNELFMVEDVCNVDLEQGLDLCKPEKVNKQSQRSRQSRQSLFTNTIKPQKDKMNIKTNKIKEFLNDLFTEFSKFHNSYYPDGRISTRSNFRWPLLIIWSIIIVFAVDKKFEVQKFLSIWINENRFYSEIWVPIAIYVCLLVLMLLSLIFFAEFAVLALRVTGVIIAVLGMIIAVLGMIIAALGATITGLLYFGHWALYKLVILSLGFKIVTPGDVCVSNTLPTHNGETALHSETTVGSDIEQIELQNMPTPVKK
What are the official names of this protein?
UPF0494 membrane protein CPT2R1.01c.
What is the protein family that this protein belongs to?
Belongs to the UPF0494 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: Y3298_MAGMM
Sequence: MGFLTPKSFGEQAEDFACKMMKKKGYHILQRNARSRYGELDIIALHGEVVVFCEVKARQGAVSGSAGEAIDGRKQRQLGRLAEAWRLANPAWMAAPCRFDAVLVAREAQGWHAEIVQDAFQLGW
What are the official names of this protein?
UPF0102 protein Mmc1_3298.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RL34_NITHX
Sequence: MKRTYQPSKLVRKRRHGFRARLATTGGRKILAARRARGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: OR1F2_HUMAN
Sequence: MERDKPVSVSEFLLLGLSRQPQQQHLLFVFFLSMYLATVLGNLLIILAISIDSRLHTPMYFFLSNMSFVDNCFSTTVPKMLANHILRTQTISFSGCLMQMYFISELADMDNFLLAVMAYDRFVAVCRPLHYTAKMIHQLCALLVTGSWVVANSNALLHTLLMARLSFCADNTIPHIFCDVTPLLKLSCSDTHLSEVMILTEAALVTITPFLCLLASYMHITCVVLRVPSTKGRWKAFSTCGSHLAVVLLFYGTIMSPYFRTSSSHSAQRDIAAAVRFTVVTPVMNPLIYSLRNKDIKGALVKVVAVKFFSVQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Putative olfactory receptor 1F2, OLFmf2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAIE_SALPB
Sequence: MSYYAFEGLIPVVHPDAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLILEAGSNLQYGCIMHGYCDTDTIVHENGHIGHGAILHGCVVGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFQGEARQLLVGSPARVLRQVTDQELHWKRLNTKEYQDLAIRCRTGLSETKPLTQVEENRPRLKGTTDVKPKSAQ
What is the function of this protein?
Overproduction of CaiE stimulates the activity of CaiB and CaiD.
What are the official names of this protein?
Carnitine operon protein CaiE.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: ARLY_ALIB4
Sequence: MSNQNNQNNQILKNTNAQILDEFNASIMFDKELYAQDIKGSIAHSKMLASQGILTNEEQKAIEKGLFQVKSEIESGEFKFSLAYEDIHMAVETRLTEIIGEPGKKLHTARSRNDQVCTDFTLYVQDKTLSIKEQLKELVATFVDIASLHTTTLIPGMTHLQHAQPLNFGFHLLAYANMFKRDYERFESSFERNNYSPLGSAALAGTPHNINRELTAQTLGFTAPTLNAMDTVSNRDFALEILFNISTTMMHISRISEELILWSSYEFQFVRMSDQYATTSSIMPQKKNPDVPELLRGKTGRVYGNLISLLTVMKGLPLAYNKDTQEDKEGVFDSVKTVEISISILNEVIKTMIVNVDKMQNACKIGHLTATDLADYLVQKQNMPFRTAYYITKDVVALANSLNKDISELSIDEIRKANDELKNINEDIVLYLDLKNSMNARNSFGGTSTKQTESQIEYFKKWLENK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.