PharMolix/UniProtQA huggingface dataset:
Protein: APC16_HUMAN
Sequence: MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
What are the official names of this protein?
Anaphase-promoting complex subunit 16, APC16, Cyclosome subunit 16.
What is the protein family that this protein belongs to?
Belongs to the APC16 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere, kinetochore.
Protein: ECFA1_STRA5
Sequence: MTNIITVNNLFFKYDSNQTHYQLENVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGQELTEDNVWELRHKIGMVFQNPDNQFVGATVEDDVAFGLENKGIPLKDMKERVDQALDLVGMSEFKMREPARLSGGQKQRVAIAGAVAMRPQVIILDEATSMLDPEGRLELIRTIRAIRQKYNLTVISITHDLDEVALSDRVIVMKNGKVESTSTPKALFGRGNRLISLGLDVPFTSRLMAELAANGLDIGTEYLTEKELEEQLWELNLKM
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LR74B_HUMAN
Sequence: MRGSCERSGEDEEQKEEAMVACGRLSGVPEAEQGPEANWDSDLETEGTDGLGELVRDTLYLRSCRAHSVVPISCFLRQGSAQELNLRHRGLGPQGARALASSLSSNPYVKRLDLRDNGLCGAGAEALAGALSKSSSIHDVDLSENQLGVAGAQALCAALTVNQAMRKMQLSGNGLEEQAAQHLAELLLAHTDLKSLDLSYNQLNDQAGETLGPALAENTGLTELNVSWNHLRGPGAVAFARGLEANIFLKVLDISYNGFGDPGASAVGEALKANNVLEELNMSNNRISAMGALSLGLGLRVNQTLRILVVSRNPMRSEGCFGLLKSVQDNPASALELLDFSDIQVNAEFDGLASSVRGILPELCIKTGACRVEYKKELLPVFRSALPASVPK
What are the official names of this protein?
Leucine-rich repeat-containing protein 74B.
Protein: GLPK_BURCM
Sequence: MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVAAEAVTRTGLNGTSIAAIGITNQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGLEAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKLAFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPDVKASSEIYGHTKTTVFASKIPLAGIAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYALEGSIFIAGAVVQWLRDGVGIIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARARGSVFGVTRGTTSAHLARAALDAIAYQSLDVLAAMEADSGISIGELRVDGGASANDLLMQFQADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRSQWQLDRRFAPSMPKEQVEQRMAGWQRAVRAAKAWADDTQ
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: Y1648_ALBFT
Sequence: MITPLAPSTPSPVLTPIEARVLGTLMEKARTVPDSYPLTLNTLLLGCNQKSSREPLMELTEADVAAALNTLKEAHLVRESSGSRTTRFEHNFQRGIGVYEQAAVLLGLLMLRGPQTAGELRLNTERWYKFADISSVEGFLEELQDRSAEKGGPLVVKLARGPGTREQRWAHLLCGPVDATQTGLGRSSEGLPGNTAERLERLESELANLRETVQKLCAELGVSPPEQV
What are the official names of this protein?
UPF0502 protein Rfer_1648.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: COAD_LACPL
Sequence: MVTAVFPGSFDPITRGHLDMIQRASRLVDRLIVAVMVNTSKQPLFTMTEKVAMISDELTGLPNVEVQAATGLTVDFMASVHATVLVRGLRNEQDFGYERDIAWMNKSLDETIETICLIARPPYAYFSSSLIKEVAKMGADVSKYVPTAVAQKLHQRLGTDQHD
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_ALIF1
Sequence: MSNRKPYVREMTRTWWKDHPFYRFYMVREATVLPLIFFTICLLVGLGSLVKGPLAWASWLDFMANPIVVALNIVALAGSLFHAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAITLLVLVIV
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CSK2B_CANAX
Sequence: MPSDPEEDYIPWIQQLCELFGHDYFVQVSQDFIEDDFNLTGLSSQVPYYREALYTILDYQVETAEDHNTDNTTTNTSNNNDSRNGTSKRNASELPNKALLAHSAELLYGLIHARYIVSKQGLTAMASKFERNDFGSCPRYFCDGMHLIPVGSTDVPGQETVRLFCPCCNDIYIPSSSRYLNIDGAFFGTTFPGLLVKMFPEIENQCRIRITKFSQNDFGLKLFGFKINELSATGPRMKWLRMHPETEGEKQELTHVNIMFQLATYMKTKRMEEDDEEEEDEVEEEDDDRTMASE
What is the function of this protein?
Regulatory subunit of casein kinase II/CK2 (By similarity).  As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity).
What are the official names of this protein?
Casein kinase II subunit beta, CK II beta.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: RS9_HERAR
Sequence: MIGNYNYGTGRRKSAVARVFIKSGSGQIVVNGKPANEYFSRETGLMVIRQPLELTNNVETFDIMVNVNGGGESGQAGAVRHGITRALIDYDATLKPELSKAGFVTRDAREVERKKVGLRKARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: COX1_DRONO
Sequence: MTFITRWFFSTNHKDIGTLYLIFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPVMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSTVEAGAGTGWTVYPPLAGNLAHAGASVDLAIFSLHLAGVSSILGAINFITTAINMKPPALTQYQTPLFVWSVLITAILLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPVLYQHLFWFFGHPEVYILILPGFGMISHVVTYYAGKKEPFGYMGMVWAMLSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGIKVFSWLATLHGGTIKWDP
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: USH1G_HUMAN
Sequence: MNDQYHRAARDGYLELLKEATRKELNAPDEDGMTPTLWAAYHGNLESLRLIVSRGGDPDKCDIWGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKLQRRHHERMERRYRRELAERSDTLSFSSLTSSTLSRRLQHLALGSHLPYSQATLHGTARGKTKMQKKLERRKQGGEGTFKVSEDGRKSARSLSGLQLGSDVMFVRQGTYANPKEWGRAPLRDMFLSDEDSVSRATLAAEPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYLSSGLHGLGREDGGLDGVGAPRGRLQSSPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDEDLEPETSPLETFLASLHMEDFAALLRQEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQAMERPPALEDTEL
What is the function of this protein?
Plays a role in pre-mRNA splicing by regulating the release and transfer of U4/U6. U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complexes from their assembly site in Cajal bodies to nuclear speckles, thereby contributing to the assembly of the pre-catalytic spliceosome on target pre-mRNAs (PubMed:34023904).  May also participate in recycling of snRNPs back to Cajal bodies during splicing (PubMed:34023904).  Plays a role in regulating MAGI2-mediated endocytosis (PubMed:24608321).  Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells.  Required for normal development and maintenance of cochlear hair cell bundles.  Required for normal hearing.
What are the official names of this protein?
pre-mRNA splicing regulator USH1G, Scaffold protein containing ankyrin repeats and SAM domain, Usher syndrome type-1G protein.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, cilium. Nucleus speckle. Nucleus, Cajal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Photoreceptor inner segment. Note=Detected at the tip of cochlear hair cell stereocilia. Recruited to the cell membrane via interaction with CDH23 or PCDH15 (By similarity). In photoreceptor cilia, detected predominantly at the cilium base (By similarity). Expressed in the pericentriolar region of the centrosome (By similarity).
Protein: MED14_MAGO7
Sequence: MAAVMMNGVGPDGAMKPNLDQKLNNHGGDTKAISSSEIVQQQTPARSLQSDNPLRMNDLPDEIVHITENFLSLNQLLSRLAQRSHNELEDTIRSLAKKPLPMPPMLNGNADHNTIEDLSNENLDKKVTLLKFAQEQHAKWVKALVITDWSKKASTLSKLIDLKVHMHTQMEKYDFVLDRMMHNKRNLAYARLPSPDLKTALEVLANGDAPWMPDLGYIPPPEMSPEDQLKWLEDLDTLLSLRLTIDDHDKIPYHFRNYRIGSGRVTFIVKGEFEVDLTIADDDPEKQYWFIDFRFLFRPAPPGLSENLRMYLELKVNEVLGAEGLAGCYKYLHELVLTHKINELRRQAMELSVGRWVDALNVERLNRSLAVQYWTSRYPAKAPNAPKSWIIIGVHSAAPSGGLRATAPTSRLALRWFRDNQEVKDIEIPLDEADLSMERILKDVIGRHTQQILTLMHTGLRNKPRFVNKEDHLVLELSRKQPSESLLTMQLTKLDSMVVRVDQIGGTFAVQPRTRPMPMAESNLNTPGRDPVAVIGWVRNTFAMEELVRRGKSQGWVVGKPPVKPDDLRNILSNREQTDAMAWFRKQGWRPQFYVLAHLSMSGDQWWLIELTTPNSNSAASTAGGIRIRTHVQLQFASKQAIMESPSFFSDLNYFTSAMISKMRDLRELHSRRINHIDQPCIRPGLSSNIRMPTIFIRTSEVLPSLSGKGSLGRWAADEVRLSVANVQSSSSTEVDRRGENRSALSTRMDSRIVIASEARLRVLDKSKFRQLSSRVDRDVAFNHKTGEFVLQLRSELGETMIDKLISRLQTIERLYEFLGSISRAPRGVQCETVTLRRVVFTYSDLPQPVSEELAALQPPTKRWKVVLDFADPRTVKLVLEKNNPHIRAVDMLQTLANSPRGLERLPFYLPTTLAVYRALDSISDAWLQLQVSRKGTFEIFTKNIDLATIRYDLPGPQARRLTLDVKLVSRRGELSWHVKRTDAEPNKSNDEFSRVLKEVWNTKSPNWKSLSTSACGPASAGVEELLKGIDKAVRTLLESPPLVLQQQQQRQPVVQPGQQPQVQNQANGVMNRGPQRPGLPGAGGLGAQMRQKQVPQAPMGNHVVDLT
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 14, Mediator complex subunit 14.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 14 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAPC1_DROME
Sequence: MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF
What is the function of this protein?
Serine/threonine-protein kinase involved in memory formation (PubMed:29473541).  Promotes long-term memory by phosphorylating meng and by regulating CrebB protein stability and activity (PubMed:29473541).  As part of ethanol response in the glia, mediates ethanol-induced structural remodeling of actin cytoskeleton and perineurial membrane topology when anchored to the membrane (PubMed:29444420).
What are the official names of this protein?
cAMP-dependent protein kinase catalytic subunit 1, PKA C, Protein kinase DC0.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Protein: FLZ15_ARATH
Sequence: MVGLSIVLEMTNNNNNNNNNNNNNNNKNPLSEGVLISPKVVNKANIIVTTAVTTDTTNLRRCYQDSGFLEHCFLCRRKLLPAKDIYMYKGDRAFCSVECRSKQMIMDEEESLRREYCSLMDVKKKKFDSPATAPSRYRRDPRNQAGGFAY
What is the function of this protein?
May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
What are the official names of this protein?
FCS-Like Zinc finger 15.
What is the protein family that this protein belongs to?
Belongs to the FLZ family.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: Y1567_XYLFA
Sequence: MRQTRVEVILPPQGVLQPCEAPELGRVDTVRDLLNQTLGWRFAYEQCAAQVRCVAAWAQAASVGQPWSADGCGEEAE
What are the official names of this protein?
Uncharacterized protein XF_1567/XF_1672.
Protein: TAM1_SCHPO
Sequence: MSVSQQLSELASKEKTVLYVADQNLEEVLCFPESTDRTTLVQLTDACLHANELAKHLEFGKPLSITNQYSRGSCVLQIAKEKKDGSGMVVSTTIAAHNALRGALKCSNALDQVISQL
What are the official names of this protein?
Uncharacterized protein tam1, Transcripts altered in meiosis protein 1.
Protein: UFO_MOUSE
Sequence: MGRVPLAWWLALCCWGCAAHKDTQTEAGSPFVGNPGNITGARGLTGTLRCELQVQGEPPEVVWLRDGQILELADNTQTQVPLGEDWQDEWKVVSQLRISALQLSDAGEYQCMVHLEGRTFVSQPGFVGLEGLPYFLEEPEDKAVPANTPFNLSCQAQGPPEPVTLLWLQDAVPLAPVTGHSSQHSLQTPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQRPHHLHVVSRQPTELEVAWTPGLSGIYPLTHCNLQAVLSDDGVGIWLGKSDPPEDPLTLQVSVPPHQLRLEKLLPHTPYHIRISCSSSQGPSPWTHWLPVETTEGVPLGPPENVSAMRNGSQVLVRWQEPRVPLQGTLLGYRLAYRGQDTPEVLMDIGLTREVTLELRGDRPVANLTVSVTAYTSAGDGPWSLPVPLEPWRPGQGQPLHHLVSEPPPRAFSWPWWYVLLGALVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSDREGFPEPVVILPFMKHGDLHSFLLYSRLGDQPVFLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPVDCLDGLYALMSRCWELNPRDRPSFAELREDLENTLKALPPAQEPDEILYVNMDEGGSHLEPRGAAGGADPPTQPDPKDSCSCLTAADVHSAGRYVLCPSTAPGPTLSADRGCPAPPGQEDGA
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation.  Ligand binding at the cell surface induces dimerization and autophosphorylation of AXL.  Following activation by ligand, AXL binds and induces tyrosine phosphorylation of PI3-kinase subunits PIK3R1, PIK3R2 and PIK3R3; but also GRB2, PLCG1, LCK and PTPN11.  Other downstream substrate candidates for AXL are CBL, NCK2, SOCS1 and TNS2.  Recruitment of GRB2 and phosphatidylinositol 3 kinase regulatory subunits by AXL leads to the downstream activation of the AKT kinase.  GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.  Also plays an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response.
What are the official names of this protein?
Tyrosine-protein kinase receptor UFO, Adhesion-related kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: DAPA_SHEB9
Sequence: MINGSIVALITPMNSDGSVDFASLERLVEFHIDQGTDAIVAVGTTGESATLPMSEHVTVVSQTVKFAAGRVPVIGGNGANATSEAVELTKSLSKVGVAAMLGVTPYYNKPTPKGLIAHYKAVAASTDIPQILYNVPGRTAVDMLPETVAELVSVSNIIGVKEATGDLSRVKRLRELCGDDFLLYSGDDATAREFLLLGGNGVISVANNIVPQAFKAMCDAALAGNAELALSIDTPLRGLYSTLFCEANPIPVKWAAHRMGLIECGHIRLPLTELSEQCHGLLIEAMTRAQIEVK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_AGRRK
Sequence: MTMTDPLGDMLTRIRNGASRRKSSVSTPASKLRARVLDVLQAEGYIRGYSVVDFGNGKSELSIELKYYEGSSVIREIGRVSKPGRRVYVSVKSIPQVANGLGIIILSTPKGVMADHQAREQNVGGEVLCSVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RNH2_METM6
Sequence: MNEDIKNNLNNLDEFSGKIIVGLDEAGRGPVIGPMVIASVKINEKDLYKLQDLGLKDSKQLSKKKREELYVKISEICNVKKIVIAPEKIDEQMEITNLNKIELSAFSKLANHFIKENENISIYIDACSSNEQSFSNQFKAKLINKNVEIIAEHKADENYKIVSAASIIAKVTRDNVIEEYKKTFGEIGSGYPSDPKTKKFLKKYVHENKGLPKIARKSWATSKNLLKEIEESKIFQWVK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_LACLA
Sequence: MSENVMTLQVITPAGMIYDHHANYITARTTNGEIGILPNMISTIAGLEIDELKVRRPDDETHVDYIAVNGGIIEIKDSLVTIVADSAERNRDIDVSRAERAKIRAEKALEVAKAEKKSDEINRAEVALHRALNRLNVSSHR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRHO_SHEDO
Sequence: MSQVVVCALYKFVTLPHYESLRAPLLAVMEASDIRGTLLLAQEGINGTVAGTQAAIDGLLAWFDTQEGLDNIVSKVSFDAQMPFYRTKVKLKKEIVTMGVEGIDPRKVVGTYVKPKDWNALISDPDVILVDTRNDYEVQIGTFKHAVNPVTETFREFPEYVKQNLDPAKHKKVAMFCTGGIRCEKSTAYLKEQGFDEVYHLEGGILKYLEEVKQEESLWEGECFVFDNRVSVNHNLEKGVYDQCNACRMPITEQDKLLPSFVQGVSCPHCIDKIPQEQRQRFIERERQVQLARQRGEAHIGSDVKQVIATRREKKDSLRKAQNEQS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: GLMU_ACIAD
Sequence: MTTTVIILAAGKGTRMRSHLPKVLQPLAGRPLLGHVIQTAKQLNANNIITIFGHGGAQVQQQFQQENIQWVEQTEQLGTGHAVQMTLPVLPHDGLSLILYGDVPLVRQQTLEKLLAVSSTTGIGMITLRVEDPTGYGRIIRESDKIQAIVEHKDASEQQRQIQEINTGIYCVSNQKLHEWLPKLSNNNAQGEYYLTDIVAMAVADGLEIASIQPDLAFEVEGVNDRLQLAALEREFQLQQAKSLMQQGVTLTDPSRFDLRGTLKIGQDVRIDINVIIEGNCELGDFVEIGAGCVLKNTKIAAGTKVQPYSIFEDAVVGENTQIGPFARLRPGAHLAAEVHIGNFVEVKNTSIGVGSKANHFTYLGDAEVGAGSNIGAGTITCNYDGANKHKTVIGDAVFIGSNSSLVAPVSIGDGATVGAGSVITRNVPENTLAFERAQQIEKANYQRPQKLKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_LACLM
Sequence: MSKEIKFSSDARTAMMRGIDILADTVKTTLGPKGRNVVLEKSYGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGLKNVTAGANPVGIRRGIELAAETAVASIKEMAIPVHDKSAIAQVATVSSRSEKVGEYISDAMERVGSDGVITIEESKGMQTELDVVEGMQFDRGYLSQYMVSNTEKMVAELDNPYILITDKKISNIQEILPLLEQILKTNRPLLIVADDVDGEALPTLVLNKIKGVFNVVAVKAPGFGDRRKAQLEDLAILTGGTVITEELGLDLKDATLEALGQAAKATVDKDHTTIVEGAGSVGAISDRVAIIKAQIEKITSDFDREKLQERLAKLAGGVAVVKVGAATETELKAMKLLIEDALNATRAAVEEGIVSGGGTALVNAIAALDKLSEEGDIQTGINIVRRALEEPVRQIAANAGYEGSVIIDKLRSEKVGTGFNAATGQWVNMIEEGIVDPAKVTRSALQNAASVAGLILTTEAVVANKPEPAAPAMPPMDPSMGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G1PDH_IGNH4
Sequence: MRDRHEIELMKRVVVGRGTRRELPKVIKALGFDGGEVLVVTGPHVWSEWGDELQGLLEKEGFKVDFVTVVEPSVEEANKVLEGLNGEPNVVVGFGGGKAIDVAKYVAMKLGRDVVSVPTATSHDGIASPFSSLKGLKGPTSVKTKTPIAVVADIEVIARAPERLNRAGIGDVLAKFSAVRDWRLAHVLKGEYYGSYAASLALMSAKHVLKYSPLLKALSEDGLRILVEALISSGVAMCIAGSSRPASGSEHLFSHALDVIANRPALHGEQVGVGTIMMLYLHGSKLWRKVRKVLRDLNLPTTAEELGVEDEKIIEALTIAHKIRPERYTILGSDGLTREAAERLARTTGVIK
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.