PharMolix/UniProtQA huggingface dataset:
Protein: NADE_SALSV
Sequence: MTLQQEIIQALGAKPHINPEEEIRRSVDFLKAYLKTYPFLKSLVLGISGGQDSTLAGKLSQMAIAELREETGDNALQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTHGVVVGTDHAAEAITGFFTKYGDGGTDINPLHRLNKRQGKQLLAALGCPEHLYKKVPTADLEDDRPSLPDEAALGVTYDNIDDYLEGKTLDPAIAKTIEGWYVKTEHKRRLPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: PGAP2_RAT
Sequence: MYQVPLTLDRDGTLVRLRFTMVALITVCCPLVAFFFCILWSLLFHFKETTSTHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLTAFAYWNHYLSCASPCPGYRLLCRLNFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLSYMLLTCILWRLTKKHTVSQEDRKSYSWKQRLFIINFISFFSALAVYFRHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITSQPEEKRF
What is the function of this protein?
Involved in the lipid remodeling steps of GPI-anchor maturation.  Required for stable expression of GPI-anchored proteins at the cell surface.
What are the official names of this protein?
Post-GPI attachment to proteins factor 2, FGF receptor-activating protein 1.
What is the protein family that this protein belongs to?
Belongs to the PGAP2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL23_STRGC
Sequence: MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEAAFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFGAEAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: NIR_ALCXX
Sequence: GLPRVAVDLVAPPLVHPHSQVAAGAPKVVQFRMSIEEKKMVADDDGTTAQAMTFNGSVPGPTLVVHEGDYIELTLVNPATNSMPHNVDFHAATGALGGAGLTQVVPGQEAVLRFKADRSGTFVYHCAPAGMVPWHVVSGMNGALMVLPRDGLRDAAGAALAYDRVYTIGESDLYVPKAADGNYSDYPALASAYADTVAVMRTLTPSHAVFNGAVGALTGANALTAAVGESVLIIHSQANRDSRPHLIGGHGDWVWTTGKFANPPQLNMETWFIPGGSAAAALYTFKQPGTYAYLSHNLIEAMELGAAAQASVEGQWDDDLMTSVAAPGPA
What are the official names of this protein?
Copper-containing nitrite reductase, Cu-NIR.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL34_NEIMB
Sequence: MKRTYQPSVTKRKRTHGFLVRSKTRGGRAVLAARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RHAT_SALA4
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKQVKQWSWETMWSVGGIVSWLILPWTISALLLPDFWAYYGQFNLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLIHTEGGRMTLLGVFVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLLLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGALVNLGFCFIRLAKVQNLSIKADFSLARPLIISNILLSALGGLMWYLQFFFYAWGHARIPAQYDYMSWMLHMSFYVLCGGLVGLVLKEWKNAGRRPVAVLSLGCVVIIIAANIVGLGMAS
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYE_OENOB
Sequence: MTEKIRVRYAPSPTGHLHIGNARTAIFNWLFARHYNGQFIIRIEDTDLARNVKDGEKSQLDNLQWLGIDWDEGPDKANSKYAPYRQTERAAQGVYQKYIDELLASGKAYKSYKTEATLKEEREAQAQAHQAPHYVYEYAGMTKEQIKDAQAKDEAAGLKSVVRFRVPENHDYQWQDLVKGEVKINSKEIGGDWVIQKADGMPTYNFAVVIDDHLMEITHVLRGDDHVSNTPKQLMVYEAFGWKAPAFGHMALIIKAETGKKLSKRDEDTLQFIEQYRELGYLPEAMFNFIGLLGWSPVGENEIFTREQFKEMFDENRFTKANAKFDAKKLAWVNNQWMRSEKEKVMPQLIHELVKAGLINDQQAKNDADHLAKIIEIAGVDGIKATSEIAPLAEYPFFKLHDISKEDRQSWLETDDGQKVAAAFTEKIKALAEDEFKAGHILQIIRDLQHDLQIKGRPLWNPIRLITTHEVQGPNLPEILAVMGKDWTIKNIQLTVAV
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_ALIF1
Sequence: MSDYKDTLNLPETGFPMRGNLANREPEMLKRWYDEDLYGEIRKAKKGKKSFVLHDGPPYANGDIHIGHALNKILKDIIIKSKTLSGFDAPYVPGWDCHGLPIELMVEKKKGKPGQKISAAEFREECRKYAAGQVEGQKESFKRLGVMGEWDKPYRTMDFGTEANIIRSLGKIADQGHLLKGFKPVHWCTDCGSALAEAEVEYQDKVSPSIDVRFVAADEAATLAKFSTPEGHQGEGELSVVIWTTTPWTLPANRAVALHADLEYVLVQVEAHGEQKAQRLILASELAKSVLDRANIEHYHNLGFAKGSDLELLQFNHPFYNFTVPAILGEHVTTDSGTGIVHTAPGHGQEDFVVGKKYDLEIANPVGSNGVYLPDTELFAGQHVFKANDSVLEVLKEKGALLHHHAYEHSYPHCWRHKTPIIFRATPQWFISMDQAGLRAKALEEVKSVEWMPEWGQNRIEGMIEGRPEWCISRQRTWGVPIALFVHKETAELHPDSLELIEKVAKLVEEKGIQAWWDVDAAELMGEEDAANYEKVLDTLDVWFDSGVTHFSVVDSREEYNFPEEERTHSADLYLEGSDQHRGWFQSSLISSVAMKGKAPYRQVLTHGFVVDGNGRKMSKSIGNVVAPKDVTNKLGADILRLWVASTDYTNEVAVSDEILKRSADAYRRIRNTARFFLANLSGFNPATDIVPAEEMVALDRWAVGRAFAAQQEIIKSYDEYNLHEVTQRLMHFCSIEMGSFYLDVIKDRQYTAKKGGHAQRSCQTALYYIVEALVRWMAPIMSFTADEIWNEMPGEREKFVFTGEWYQGLFDLAEGEEFNNEFWTEIQAVRASVNKLLEAARGEKVIGGALQAEVTLYADDALIAKINKLEDELRFVLLTSAATVKPLSEKTESAKATELDGLFVDVAASEAAKCERCWHHVADVGTIEGHEEVCGRCVSNVDGEGEERKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_TOLAT
Sequence: MNPIVKTFPYGQHTVTIETGVMARQATAAVMVSMDDTAVLVTVVGKKEAVEGRDFFPLTVNYQERTYAAGRIPGGFFKREGRPSEGETLTARLIDRPIRPLFPEGFLNEVQVVATVMSVNPAVSPDIVAMIGTSAALAISGIPFNGPIGAARVGYINDQYILNPSVVELQESKLDLVVAGTAAAVLMVESEAAILPEEVMLGAVVYGHDQLQTVIKAVNEFAAEVGTKPWNWVAPAANVTLKAKIAELAVAAIGEAYRITEKAVRYDAISALKQRIVAEIVAADETQDAGEVADLFHELESDVVRGRILRGEPRIDGRDPQMIRALSVGTGVLPRVHGSALFTRGETQALVACTLGTERDAQTIDEITGERTDRFMLHYNFPPYCVGETGMMGSPKRREIGHGRLARRGVSAVIPSQAEFPYVVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKASVAGIAMGLVKEGDSFVVLSDILGDEDHLGDMDFKVAGTSEGVTALQMDIKIEGITKEIMQIALKQARDARLHILTVMDKAIGVARDDISDFAPRIHTIKINPEKIKDVIGKGGSVIRALTEETGTTIELEDDGTVKIAAVSGEAAQEAIRRIQALTADVEIGRIYEGKVTRLAEFGAFVNILPGKDGLVHISQITDERVKDVSDYLKVGDMVRTKVLEVDRQGRIRLSIKEAKRDELPAAESVAESAPAQEAVVEQVPMTE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_ERWT9
Sequence: MATEYAIIAGGCFWCTEAVFKQIHGVVSVESGYIGGHTENPTYKQVCGGDTGHAEAIRIGFDPEKVSFGDLLDISFATHDPTQLNRQGNDIGTQYRSAIFPVSEEQLEEAKMAIARAQSEHNDAIVTTIEAHSTWYPAEDYHQDYWAGEGQGNRYCLAVIPPKLQKLHKRFAAYTAPE
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: KIF3C_HUMAN
Sequence: MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPAVFEMEFSHDQEQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPQRPPPSTTHASLASASLRPATVADHE
What is the function of this protein?
Microtubule-based anterograde translocator for membranous organelles.
What are the official names of this protein?
Kinesin-like protein KIF3C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ESCA_ORYLA
Sequence: IRTHTLPCKCPICGKAFSRPWLLQGHTTHHTGEKPFSCQHCNRAFA
What are the official names of this protein?
Escargot/snail protein homolog.
What is the protein family that this protein belongs to?
Belongs to the snail C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XYLT1_PANTR
Sequence: MQAAPCARRLARRSHSALLAALTVLLLQTLVVWNFSSLDSGAGERRGGAAVGGGEQPPPAPRRERRDLPAEPAAARGGGGGGGGCGGGGRGPQARARGGGPGEPRGQQPASRGALPARALDGYFSHRPKEKVRTDSNNENSVPKDFENVDNSNFAPRTQKQKHQPELAKKPPSRQKELLKRKLEQQEKGKGHTFPGKGPGEVLPPGDRAAANSSHGKDVSRPPHARKTGGSSPETKYDQPPKCDISGKEAISALSRAKSKHCRQEIGETYCRHKLGLLMPEKVTRFCPLEGKANKNVQWDEDSVEYMPANPVRIAFVLVVHGRASRQLQRMFKAIYHKDHFYYIHVDKRSNYLHRQVLQVSRQYSNVRVTPWRMATIWGGASLLSTYLQSMRDLLEMTDWPWDFFINLSAADYPIRTNDQLVAFLSRYRDMNFLKSHGRDNARFIRKQGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRRFVEYVTFSTDDLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRITNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKFEAVVNQEIIGQLDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVTLTLYHSFARLGLRRAETSLHTDGENSCRYYPMGHPASVHLYFLADRFQGFLIKHHATNLAVSKLETLETWVMPKKVFKIASPPSDFGRLQFSEVGTDWDAKERLFRNFGGLLGPMDEPVGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIESTAEFTHYKPPLNLPLRPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEALKLHNGPLRNAYMEQSFQSLNPVLSLPISPAQVEQARRNAASTGTALEGWLDSLVGGMWTAMDICATGPTACPVMQTCSQTAWSSFSPDPKSELGAVKPDGRLR
What is the function of this protein?
Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN.  Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein.  Required for normal maturation of chondrocytes during bone development, normal onset of ossification and normal embryonic and postnatal skeleton development, especially of the long bones.
What are the official names of this protein?
Xylosyltransferase 1, Peptide O-xylosyltransferase 1, Xylosyltransferase I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family. XylT subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: TRA9_MYCTU
Sequence: MPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
What is the function of this protein?
Involved in the transposition of the insertion sequence.
What are the official names of this protein?
Putative transposase for insertion sequence element IS986/IS6110, ORFB.
Protein: SSPN_BACAC
Sequence: MGNPKKNSKDFAPNHIGTQSKKAGGNKGKQMQDQTGKQPIVDNG
What are the official names of this protein?
Small, acid-soluble spore protein N, SASP N.
What is the protein family that this protein belongs to?
Belongs to the SspN family.
What are the subcellular locations of this protein?
Spore core.
Protein: NEP1_AERPE
Sequence: MKIVFLECSVELVPRSLWSHPQVLKSARRYGIEPGDLLLDKSLHYNAMAELPAKWKRGRPDILHVALLTTTDSPLYNEGLLRIYFQVYDGRLFEVGTGVRVPKNYERFRGLVAQLLKTERVPPGEGEALIRLHSRSLAEFVEREGRFILMWEKGSPTTTTYVAARALSTGLPIGVGCFPRGEFKRSTLRKASEAYSIMGGAPLKTWGVASRIVYALERLKSPFT
What is the function of this protein?
Methyltransferase involved in ribosomal biogenesis.  Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase Nep1, 16S rRNA (pseudouridine-N1-)-methyltransferase Nep1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Protein: NAGB_ACTP7
Sequence: MRLIPLQTSEQVSRWAARHIVERINRFQPTADRPFVLGLPTGGTPLQTYKELIRLYQAGEVSFQHVVTFNMDEYVGLPKEHPQSYHTFMYRNFFDHIDIQPQNINILNGNTEDHDAECRRYEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLGSRTRIKTLTEDTLIANSRFFDNDITKVPKYALTVGVATLLDAEEVMLLITGYNKALALQACVEGSVNHMWTVSALQLHKRGIVVCDEPATQELKVKTVKYFTQLETQAIQSVL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: GLYA_BACC0
Sequence: MDHLKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRVKEIFGAEHVNVQPHSGAQANMAVYFTILEQGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDAESHRINYDDVLAKAKEHKPKLIVAGASAYPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGGMILCEEQFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEDMDEIASLIAYTLKNHENEAALEEARKRVEALTSKFPMYTDL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_STAEQ
Sequence: MAGGPRRGGRRRKKVCYFTANGITHIDYKDTELLKRFISERGKILPRRVTGTSAKYQRMLTTAIKRARHMALLPYVKEEQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: NRFB_HAEIN
Sequence: MIFKVKFEVTQMILTSLINKSAKALVIVAFVAAPFLAHADDAQKPAVHVTYEPQLDNQRDPNQYCAKCHKFDKIDKNQTLDQSGGELHFGKFHGAHLDKKNPNNGKAITCVSCHGNISENHRRGAKDVMRFEGDIFGNKKPMYSVQEQNQVCFACHQPDKLREKLWAHDVHAMKLPCASCHTLHPKEDAMKGIQPKQRVKLCVDCHGEQQKRKAEQDKLIEQKDKL
What is the function of this protein?
Plays a role in nitrite reduction.
What are the official names of this protein?
Cytochrome c-type protein NrfB.
What are the subcellular locations of this protein?
Periplasm.
Protein: SKI_XENLA
Sequence: METVSRSSFQPHAGLQKTLEQFHLSSMSSLGGPAAFSARWTQDLYKKECGKEPPEPILHLPSQPPPVIPGGPLFMPSDRSTERCETILEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINAVCDELHVYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALMYGGSYPPRCAKKSDFPPGPLELELTEGSFKVYHECFGKCRGLFVPELYGHPSAPCIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLARDGVGGDDELARLGRLLEEIKEKFDYSNKYKRKAARLSSEPVAKKAKADDSIIHSPSSAEKDKSSSWLRNLSNINKNAGYVHPRQRLSAFRPWSPAISANDKELSTHLPALIRDSFYNYKSFENLVAPNVALTPPVQQKVITSPPCVPAVPRSTQSSGSPPQSRKRRPTAELPIVPEAPAPPVPIREEEKESETEIEVESREECTFTSSLSSLSSPSFTSSSSAKELSSPGMLAPTVINTSYEVASHNDQHCSGLEAELEHLKQALDSGLDSKEAKEKFLHEVVKMRVKQEEKLNAALQAKRSLQQELEFLRVAKKEKLREATEAKRNLRKEIERLRAEHEKKMKEANESRLRLKRELEQARQIRVCDKGCEAGRIRVKYSAQIEELQSKLQHAENDREQLRTDLVHEREAREHLEKVVKDLQEQLWSKTSHLPSSEHTRKDIEN
What is the function of this protein?
May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage.  May function in TGF-beta signaling (By similarity).
What are the official names of this protein?
Ski oncogene, Proto-oncogene c-Ski.
What is the protein family that this protein belongs to?
Belongs to the SKI family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OCC1_BOVIN
Sequence: MGCGNSTAASAGAGQGPAGAAKDVTEESITEDDKRRNYGGVYVGLPSEAVNMVSNQTKTVQKN
What are the official names of this protein?
Overexpressed in colon carcinoma 1 protein homolog, OCC-1.
What is the protein family that this protein belongs to?
Belongs to the OCC1 family.
Protein: ALLA4_DELRA
Sequence: LPVYNFGL
What is the function of this protein?
May act as a neurotransmitter or neuromodulator.
What are the official names of this protein?
Allatostatin-A4, AST-A4, LPVYNFGL-amide.
What is the protein family that this protein belongs to?
Belongs to the allatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL25_PARD8
Sequence: MKTFELEGKGREIVARSADQKRALKAMRKNNEIPAVLYGGEKVTHFTVTKEAVRKLVYTPEIFVVELSIDGNKTMAIVKDMQFQPVTDEILHMDFLEVSKDKAVVMEVPVVLEGHAEGVKAGGKLSLQMRKLKVKAIYDQIPEKLTINVDHLGLGKTMQVGALHFEGLELMNAKNAVVCAVQLTRAARGAQAKG
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: AFG1L_HUMAN
Sequence: MAASWSLLVTLRPLAQSPLRGRCVGCGAWAAALAPLATAPGKPFWKAYTVQTSESMTPTATSETYLKALAVCHGPLDHYDFLIKAHELKDDEHQRRVIQCLQKLHEDLKGYNIEAEGLFSKLFSRSKPPRGLYVYGDVGTGKTMVMDMFYAYVEMKRKKRVHFHGFMLDVHKRIHRLKQSLPKRKPGFMAKSYDPIAPIAEEISEEACLLCFDEFQVTDIADAMILKQLFENLFKNGVVVVATSNRPPEDLYKNGLQRANFVPFIAVLKEYCNTVQLDSGIDYRKRELPAAGKLYYLTSEADVEAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTVADCTFEELCERPLGASDYLELSKNFDTIFLRNIPQFTLANRTQGRRFITLIDNFYDLKVRIICSASTPISSLFLHQHHDSELEQSRILMDDLGLSQDSAEGLSMFTGEEEIFAFQRTISRLTEMQTEQYWNEGDRTKK
What is the function of this protein?
Putative mitochondrial ATPase.  Plays a role in mitochondrial morphology and mitochondrial protein metabolism.  Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain (PubMed:26759378, PubMed:27323408).  Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress (PubMed:27323408).
What are the official names of this protein?
AFG1-like ATPase, Lactation elevated protein 1, Protein AFG1 homolog.
What is the protein family that this protein belongs to?
Belongs to the AFG1 ATPase family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: ILVC_CORK4
Sequence: MAIKTYYDDDADLSIIQGRKVAVIGYGSQGHAHAKCLRDSGVEVRIGLREGSKSAEKAKEAGFEVLSNAEAAEWADLIMILAPDTSQIAIFEKEIEPHLKDGDAIFFAHGLNIHFKKIVAPKGVTVAMVAPKGPGHLVRRQFTEGKGVPSLIAVENDPTGEGTALALSYAAAIGAGRAGVIETTFREETETDLFGEQAVLCGGLEKLMMTGFEVLVEAGYAPEMAFFEVCHEMKLIVDLIFEGGLSNMNYSISETAEFGGYVSGPKIIDDHVKESMKKVLSEIQDGTFVDAMFKDVDAGQPGLKGLREEYANHPLEKAGKDMRSMMSWIANPLDETA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: GPT_HUMAN
Sequence: MWAFSELPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGVISGAVFLIILFCFIPFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNLRWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLYHNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCPRHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNNMTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV
What is the function of this protein?
Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
What are the official names of this protein?
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, GlcNAc-1-P transferase, G1PT, GPT, N-acetylglucosamine-1-phosphate transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SPTC1_PONAB
Sequence: MATATEQWVLVEMVQALYEAPAYHLILEGILILWIIRLLFSKTYKLQERSDLTVKEKEELIEEWQPEPLVPLVPKDHPALNYNIVSGPPSHKIVVNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCRQIHKALQGISGLKVVGEPLSPAFHLQLEESTGSREQDVRLLQEIVDQCMNRSIALTQARYLEKEEKCLPPPSIRVVVTVEQTEEELDRAASTIKEVAQAVLL
What is the function of this protein?
Serine palmitoyltransferase (SPT).  The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core.  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference.  The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA.  The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference (By similarity).  Required for adipocyte cell viability and metabolic homeostasis (By similarity).
What are the official names of this protein?
Serine palmitoyltransferase 1, Long chain base biosynthesis protein 1, LCB 1, Serine-palmitoyl-CoA transferase 1, SPT 1, SPT1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.