PharMolix/UniProtQA huggingface dataset:
Protein: LFTR_PSEAB
Sequence: MLTWLSRTDFDFPPLDKALQEPNGLLAAGGDLNPQRLVAAYRHGCFPWYQDGQPILWWSPDPRTVLFPDELHVSRSLAKCLRQQRFEVTFNHDFRAVIQACAAPRDYADGTWITTPMQLAYQELHLRGIAHSVEVWQERQLVGGLYGLAMGRLFFGESMFSRADNASKVGFVTLVRHLRDAGFVLIDCQMPTRHLHSLGARAISRGEFADYLQRYRDQPPTGDLDF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPS_SCHPO
Sequence: MYDDIFFYLALWVIQSVYGAWDWAKNWVFWTCSYLLNFLYHHHCSRDLIRRDTKKLKKKPKHIAVIIECVEDGGIEGLIHDACELSAWCVCSNIRELTIYERKGFLKQSPEAVEKAIYSHLPFYLGGDKCTVHVTNPCSPDEKNQNDCVDLKVHLIAKEDGRDAIIDLTRGLADLCTKKVISSTQVTLELIDKELKESVIPEPDLLIIFAPLLKLQGFPPWQLRLCEIFHDPILYTTNYLTFFKALVHYSNAEMRLGH
What is the function of this protein?
With SPAC4D7. 04c, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery.  Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER).
What are the official names of this protein?
Dehydrodolichyl diphosphate synthase complex subunit nus1.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RIMP_ALKMQ
Sequence: MNKIESITEDLITPIVEAEQFELVDIEFKKEGPHKYLRVYIDKPGGITLDDCQKVSEGLSKKLDEADPIVENYFLEVSSPGLDRPLKREVDFLKFKGEMIELKLYEAIDGQKTIEGELVGLIDDKIVIKISETEEVEMPREKVAITKLAIKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_STRZJ
Sequence: METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVDRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALAEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKWDMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACRF_ASPA1
Sequence: MHVQSKAPKDLHPQAQMTMLQRLYKLGDMFTVDTWPLMDQMYLVANPKLAHQVSQDSSPFPKHPMITRFLKPLTGYNSVLAANDAKWKELRSLFAPGFSNAHLMTMVPLMVEKTEVFCDLLSEYAAKHELFSMEPMAARLTIDIIGIVVLGVDFKSLTRRDELVEAFRHLLDLLPNGQTLDINPVTHYLRRKYANTMDNYIRRVLRDRAANGANKKFRTLMDIAIERYEQLPNGSLFDCGFEQLAVDNLKTFVFAGHDTSSTTLSNIYHLLSKHPEVLAKVIEEHDQVLGKDTAAIGQLIRDQPSIINKLPYTTAVIRETLRLYPASGSLRMAPKDTTFHPDKAPAVTVPKGSLIWVGIHTIHHDAEFFPCPDEFHPERFMTAKTITLADGRTEAVTAGWNGHAPPADAYRPFEKGPRMCIGSEMAMIEIRVVLAMTLRRFRFESAYAEYRRRHPDEVEAAGGRTEAFGDEAYQVFSSTAKPKSGVPMYVYTKE
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the cluster that mediates the biosynthesis of acurin A, a highly reduced polyketide coupled to a serine via a peptide bond (PubMed:32234543).  The activities of the highly reducing polyketide synthase acrA and the nonribosomal peptide synthetase acrB are collectively responsible for the synthesis of the acurin A core structure with a heptaketide backbone produced by acrA covalently fused to a L-serine by acrB (PubMed:32234543).  After the formation of the PK-NRP hybrid product, it is detached from acrB by reductive release to set up the formation of the lactam ring by aldol condensation (Probable).  The hydrolyase acrC then catalyzes water loss to generate a double bond in the ring (Probable).  This double bond is probably reduced, which is followed by three oxidations at C-22 to generate the carboxylic acid moiety, involving probably the FAD-binding monooxygenase acrE and the cytochrome P450 monooxygenases acrD and acrF (Probable).  Finally, a last methylation step performed by the O-methyltransferase acrG leads to the production of acurin A (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase acrF, Acurin A biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: CINA_STRPN
Sequence: MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIFFTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPMVLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVRHIAVMHAFNLVRKALLSD
What are the official names of this protein?
Putative competence-damage inducible protein, Exported protein 10.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: LIN52_TETNG
Sequence: MASPNGGDDFESSLLSFEKLDRASPDLWPEQLPGVVEFAASCKNPITDSPPKWMAELESEDYEMLKELGSLTTANLMEKVRGLQNLAYQLGLEESREMTRGKFLNILESFKK
What are the official names of this protein?
Protein lin-52 homolog.
What is the protein family that this protein belongs to?
Belongs to the lin-52 family.
Protein: ZUPT_ECODH
Sequence: MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
What is the function of this protein?
Mediates zinc uptake.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: G6PI_SPHAL
Sequence: MTIASDAWQALADWQPQKLTDLVAADPDARLQALVRNVADIRFDFAKTHLDAAAIAILANLAEAQDFGGRRKTLFSGGIANPTENRAAEHSAERGDGAPESVHAAQALHQRMRMMIDAIEAGAFGEIRHLLHIGIGGSALGPDLLVDALGRHSDRYDVAVVSNVDGAALDEAFAKFSPEHTLVAVASKTFTTTETLLNANSALQWLDEAGVADPVGRFIALTANPGRAMEWGIDETRILPFSETVGGRYSLWSSIGFPAALALGWDAFADLLEGAAEMDRHFRLADGADNICLLAAFADQVYANRLGCQTRAVFAYDERLRLLPAYLQQLEMESNGKSVTLDGAPLAQHSAPVTWGGVGTDAQHAVFQLLHQGTHLVPVEFIVAREPDHLLDDAHHETLVANCIAQGAALMAGRASDDRARAYPGDRPSTTILLDQVSPRSLGALIAFYEHRVFANAVLLGVNPFDQFGVELGKEMAKGLAEGTVDFDPATQALMKAALGD
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_METFK
Sequence: MKFLYDLFPVILFFIVYKLFGIYEATAAAIAATIAQIAWAKITTGKVDNALIMSGVIIVVFGGATLWLQDESFIKWKPTILYWVFTVGLLGSQWLFKRNLIRGLMEKQITMPDPIWSRLNLAWAIFFLLLGFLNLYVAYNYSTDLWVDFKLFGTMGLMFVFVIGQTLLLNKHITEQDKK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FUSA5_GIBZE
Sequence: MALTEGISELLLSKPVVLGLAACALLFLIGRAFEPTVDALEPPMLRPSIPIFGHFYSMMKDQEAFFKRLDKKYHMPIATVPILKYKMYAITDPILVQSAYCNKNLSFTPFAINGAQKVTGFDDDYHKVLMETNVLPEYFKSLYDGTTAQHIHQLNVTSLKHVSQHINSIQENGMTIDNTYLWLRNLMTVATCEALYGPDNPIRSDSLVEDIWTFETGLAYLFFHIFNSKTLQRTKEARRRIQLALGKWCTNMRQDDERVSAYIRNRVGILRNYGVEGQKLGDIEVGLIHVPTSNSIPTLFWFFMHVFTRPDVVEQMRAEVEHIVQRGPDETVTVNIDDILERCPLMISAYREASRLCNGFTCNRIVMEETTITDRHGRSYLLKKGSSVKMPAGVMHASQEVWGEDAAVFRADRFLDKGLTSEQAKLRRAALTPFGGGAHMCPGRNFATAEIYGFMTALLLGYNVEPVDGKWDAFKPPPMATCPQSTSVCKPEDEASVCGTRLIRRSGWEGAQWKFVSGKVTE
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the lipopeptide fusaristatin A (PubMed:25412204).  Fusaristatin A consists of a polyketide chain linked to three amino acid residues glutamine (Gln), dehydroalanine (dehydro-Ala), and beta-aminoisobutyric acid (PubMed:25412204).  The biosynthesis starts with formation of a linear polyketide chain by the highly reducing polyketide synthase PKS6 (PubMed:25412204).  The gene cluster does not contain an acyl-CoA ligase or an acyl-transferase, and it is therefore predicted that the polyketide is transferred directly to the nonribosomal peptide synthetase NRPS7 (Probable).  Modules 1-3 from NRPS7 incorporate dehydro-Ala, Gln, and beta-aminoisobutyric acid in the compound, which is released by cyclization (PubMed:25412204).  The beta-aminoisobutyric acid units are most likely not freely available to the NRPS, but can be synthesized from thymine, which requires a dehydrogenase, a monooxygenase, and an aminotransferase.  The fusaristatin A cluster contains a cytochrome P450 monooxygenase (FGSG_08207) and an aminotransferase (FGSG_17085), which theoretically can perform two of the enzymatic steps (Probable).  The enzymes may however also be involved in biosynthesis of dehydroalanine or modification of the polyketide (Probable).  The dehydro-Ala residue can be a result of cyclization, where serine is dehydrated (Probable).  The last gene of the cluster encodes a protein with an A/B barrel domain found in variable enzymes, which hampers functional prediction (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase FGSG_08207, Fusaristatin A biosynthesis cluster protein FGSG_08207.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YIDD_PSEE4
Sequence: MRKLALVPIQFYRYAISPLMASHCRFYPSCSCYAYEAIENHGLLRGGWLAVRRLGRCHPWNDGGFDPVPPAPSSRTSSIAE
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NKP2_KLULA
Sequence: MLHEVLYKHLDGILVSRLYTEDQFVDLFSRTIPESNTVIASQLYKSYEENDQRIIEKIDKLIDNKLSLIRVELEREQIEDSISLEEVNKLLHSIDDMLQQHLNQLNIELDNKNTKLLKYAMELSDIEAIDTSMYDNVAKLITDMETNQPSS
What is the function of this protein?
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis (By similarity).  Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (PubMed:29046335).
What are the official names of this protein?
Inner kinetochore subunit NKP2, Constitutive centromere-associated network protein NKP2.
What is the protein family that this protein belongs to?
Belongs to the NKP2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: GGPPS_HUMAN
Sequence: MEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE
What is the function of this protein?
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, myofibril, sarcomere, Z line.
Protein: CARA_RUEPO
Sequence: MAQNPLSKPTACLVLADGTVFYGTGFGATGQTVAELCFNTAMTGYQEIMTDPSYAGQIVTFTFPHIGNVGVTPEDDETTDPVAAGMVVKWDPTAASNWRAAEELKGWLARRGRIAIGGVDTRRLTRAIRQQGAPHVALAHDPEGKFDLAALIAAARGFAGLEGMDLAKDVTCAQSYRWDEMRWAWPEGYARQEAPKHKVVAIDYGAKRNILRCLASSGCDVTVLPATATAAEVLAHAPDGVFLSNGPGDPAATGEYAVPMIREILDTTSLPVFGICLGHQMLALALGGRTVKMNHGHHGANHPVKDLETGKVEITSMNHGFAVDAQSLPEGVVETHRSLFDGSNCGIRMSERPVFSVQYHPEASPGPQDSFYLFERFAAAMDAQKAEV
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: RLMH_PARXL
Sequence: MKLHILAVGHKMPDWIATGFDEYAKRMPPELRIELREIKPEQRSSGRPAESVMAAERIRIEAALPKNARIVALDERGKDWTTMQLAGALPSWQQDGRDVAFLIGGADGLDPDLKARADMLLRVSSLTLPHAMVRVLLAEQLYRAWTITQNHPYHRV
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU_CERSK
Sequence: MPRAIWKGWLAVGQVSCAVALHAAASTSDRVSFHTVNRKTGNRVRREFVDAVSGKPVPREDQVKGYEVAPDEFVQIDPDEIAATIPDSDKCLRIDAFVPCREVDGAYFDKPYYLTPAGDAALEAFALIREGMRARKAAALARTVLFRRLRTVMVRPHGAGLIAHTLNFDYEVRSSAEAFSEIPKLKVKGEMLELAKHIIGTKAGTFDPTAFDDRYDAALAELVKAKLEGRKPKRKAAPKKAREPSDLMAALRESVAATERPRRRKAG
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity.  Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA.  Recruits and stimulates the ligase activity of LigD.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: TRPA_PSEPW
Sequence: MSRLEQRFAELKAEGRSALVTFVTAGDPGYDASLQILKGLPAAGADVIELGMPFTDPMADGVAIQLATLRALEAGQNLAKTLQMVREFRVDNQATPIVLMGYYNPIHRFGVEKFVAEAKEAGVDGLIIVDLPPEHDAELATPAQAAGIDFIRLTTPTTDDARLPRVLERSSGFVYYVSVAGVTGAGSATTEHVTEAIARLRRHTDLPISVGFGIRTPEQAAAIARLADGVVVGSALVDKIAQAKDADQAVADVLSLCSALAEGVRGARR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ASAH1_PANTR
Sequence: MPGRSRVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGPVPWYTINLDLPPYKRWHELMLDKAPMLKVIVNSLKNMINTFVPSGKIVQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLSLNERFSINGGYLGILEWILGKKDAMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
What is the function of this protein?
Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (By similarity).  Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (By similarity).  Has a higher catalytic efficiency towards C12-ceramides versus other ceramides (By similarity).  Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatty acids and sphingosine (By similarity).  For the reverse synthetic reaction, the natural sphingosine D-erythro isomer is more efficiently utilized as a substrate compared to D-erythro-dihydrosphingosine and D-erythro-phytosphingosine, while the fatty acids with chain lengths of 12 or 14 carbons are the most efficiently used (By similarity).  Has also an N-acylethanolamine hydrolase activity (By similarity).  By regulating the levels of ceramides, sphingosine and sphingosine-1-phosphate in the epidermis, mediates the calcium-induced differentiation of epidermal keratinocytes (By similarity).  Also indirectly regulates tumor necrosis factor/TNF-induced apoptosis (By similarity).  By regulating the intracellular balance between ceramides and sphingosine, in adrenocortical cells, probably also acts as a regulator of steroidogenesis (By similarity).
What are the official names of this protein?
Acid ceramidase, AC, ACDase, Acid CDase, Acylsphingosine deacylase, N-acylethanolamine hydrolase ASAH1, N-acylsphingosine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acid ceramidase family.
What are the subcellular locations of this protein?
Lysosome. Secreted. Note=Secretion is extremely low and localization to lysosomes is mannose-6-phosphate receptor-dependent.
Protein: TATA_ECOLI
Sequence: MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side. Note=Abundant all over the membrane, but is more concentrated at the cell poles.
Protein: TM160_DANRE
Sequence: MASIRWLMGSRLSRFVCPFAQLVRQPVLRYVRPPVRALHRGSVRRAAEKNPLNSRARAVEQQYITELDKADALMLRKSHETGFLSWFRNGLLATGIGVIAFVQSDVGREAGYAFFILGGMCVSFGGASYVTSLLSLRRIMLLSLPAVLLHTAVVSSAALFWLCAVSLYIGRLEVEIIHDEDDEEHGADESSECAECRARRDREKGQDK
What are the official names of this protein?
Transmembrane protein 160.
What is the protein family that this protein belongs to?
Belongs to the TMEM160 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MAB3_CAEEL
Sequence: MLTEDPVSEICEAKAVDELAEQEKNYYCQRCLNHGELKPRKGHKPDCRYLKCPCRECTMVEQRRQLNNLLSKKKIHCTPATQTRDGKRVRDPHCARCSAHGVLVPLRGHKRTMCQFVTCECTLCTLVEHRRNLMAAQIKLRRSQQKSRDGKEPKRNSRRKSKDMDMEMMVVTATDGQKIIGTSASPSPSSTTDTMSPSLSMSPPCSPSPLLAQYTLTLAAPIPIYPPIPMNQQLISLQQQQFLMSIIQNMAPSIGQQAPLLPGISAGSVSSAAILNEFWSMYLKNYGLQA
What is the function of this protein?
Transcription factor which binds the DNA motif 5'-[CGA][TCA][TA]ACAATGT[AT][TGA]C-3', probably as a monomer (PubMed:9490411).  Acts partially redundantly with the transcription factor dmd-3 to coordinate tail tip cell fusion and retraction and thereby regulate male tail tip morphogenesis (PubMed:18550714, PubMed:21408209).  Promotes male-specific development of two tissues, the peripheral nervous system and the intestine (PubMed:9490411).  In the peripheral nervous system, directs differentiation of sensory ray neuroblasts into peripheral sense organs (PubMed:9490411).  In the intestine, causes repression of vitellogenin gene transcription (PubMed:9490411).
What are the official names of this protein?
Protein male abnormal 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: NF2L3_MOUSE
Sequence: MKLPKPWWAGGGLLQLTILLSLVGLRVDLDLFLPPPAAALWEELLPLCPTRPASASNPFSASEGWERTPLLPAKGRLLHEVRALGVPFIPRTRVDAWLVHSVATGNADGAHGLLGTAASSAVGDGGQSASAGGGDPRAAHSSPLAAEEEEEKAAEPTAQVPDAGGCGSQENGMLREKSEAVDHSSQQEENEEGVSAQAKSRQQSKTEEHKMACASAREAEKITEARNESHLHWSDTSFSLEDLFQLLSSQPEHSLEGISVEDIPPFLSSVCESVNSSAQNINLSQAISHDVNLHEAMLLYPNNTFRRDPSARSSQAQEPFLQLNPHTNPEQATPAMSLPPFDNQMRNLTSQDLLYDLDSNIFDGINLMSLATGFSPLEVSQLFEEPDSGLSLNSSYNSTSLTNSYRIYDGTVGYNSDLQSLCHDLGAVGGCYPEPHKHCHMDHRTIAGFHVSLECQQVFHDHTYHLQSGASEPTSESFAWSEKSQKTSGCLDNPDRNLSRDEQRAKALHIPFSVDEIVRMPVDSFNSMLSRYYLTDLQVSLIRDIRRRGKNKVAAQNCRKRKLDIILNLEDDICNLQAKKEALKNEQTQCSKAIDIMRQKLHGLHQDVFNRLRDDQGRPVNPSQYALQYSHDGTVLIVPKELISSGHKKEAPKGKRERRN
What is the function of this protein?
Activates erythroid-specific, globin gene expression.
What are the official names of this protein?
Nuclear factor erythroid 2-related factor 3, NF-E2-related factor 3, NFE2-related factor 3, Nuclear factor, erythroid derived 2, like 3.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. CNC subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURD_SHEVD
Sequence: MELDNSHLVLGLGATGLSVVRYLCRQGITPLVMDSRDQPPGAEQLALEFPEVNLITGGFDCRYLVQASQIVISPGIAIDTPEIRAAIDMDIEVIGDVELFARAIKDRSPCVIGITGSNGKSTVTTLVGEMAKAAGLNYAVGGNIGIPVLDLLQKPVDLYILELSSFQLETTHSLNCISATCLNISEDHMDRYSDLEAYRQAKLALYDQSKRALFNREDSLTQPNDPMNQNSFGLTSPVNDEWGVKDGKIVHGTTEIASLQDVAIVGSHNHANLIAAMALAYHAGIDKEPMIQVAKNFTGLAHRCELVANIAAVAYVNDSKATNVGATVAALEGLGEHLGDIILIVGGDGKGADFTPLETVFNKVAHLITLGKDGDKIAALKEHSHKADSMADAVKQAAELATAGDIVLLSPACASLDMYKNFMARGDDFRQLAQALSVETLDSEASADV
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_PSEA8
Sequence: MRRIAVVGAAGRMGKNLIEAVQQTGGAAGLTAAVDRPDSTLVGADAGELAGLGRIGVPLSGDLGKVCEEFDVLIDFTHPSVTLKNIEQCRKARRAMVIGTTGFSADEKLLLAEAAKDIPIVFAANFSVGVNLCLKLLDTAARVLGDEVDIEIIEAHHRHKVDAPSGTALRMGEVVAQALGRDLQEVAVYGREGQTGARARETIGFATVRAGDVVGDHTVLFAAEGERVEITHKASSRMTFARGAVRAALWLEGKENGLYDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_HERA2
Sequence: MSLEKDKSTVINNYKLHESDTGSADVQIALLTDRINQLIEHLKLHKQDHHSRRGLLKLVGRRRRLLAYLSKKDNARFRAVSERLGLRIKA
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.