PharMolix/UniProtQA huggingface dataset:
Protein: NAPA_VIBCH
Sequence: MKMTRRAFVKANAAASAAAVAGITLPASATNLIASSDQTAIHWDKAPCRFCGTGCSVLVGTQDGRVVATQGDPEAPVNKGLNCIKGYFLSKIMYGQDRLKTPLLRMKDGQYHKDGEFTPVSWDTAFDVMAEKWKASLKTKGPTSVGMFGSGQWTVMEGYAAVKLMKAGFRSNNIDPNARHCMASAVVGFMRTFGIDEPMGCYDDFEHADAFVLWGSNMAEMHPVLWTRITDRRLSHPHVKVNVLSTYYHRSFELADHGYIFHPQSDLAIANFIANYIIQNDAVNWDFVNKHTHFKQAVTDIGYGLRDDHPLQKKAKNANSGDVSDISFEEYKKSVAPYTVEKASEISGVSPDKLITLAKQYADPNTKVMSLWTMGMNQHTRGVWMQSLVYNLHLLTGKIATPGNSPFSLTGQPSACGTAREVGTFAHRLPADMVVANPKHRAIAEKVWKLPEGTIPEKPGFHAVQQDRMLKDGVLNCYWVQCNNNMQAGPNINEERLPGYRNPENFIVVSDAYPTVTAQAADLVLPTAMWVEKEGAYGNAERRTQVWYQQVKTVGESHSDSWQVIEFSKRFKVEDVWPEELLAKAPQYRGKTLYDVLFKNGQVDKFPLSEARELNDDAHHFGFYIQKGLFEEYAEFGRGHGHDLAPYDVYHQVRGLRWPVVDGKETKWRFKEGSDPYAKAGSGWDFYGKPDGKAWIISSPYEAPPEMPNEEYDLWLCTGRVLEHWHTGTMTRRVPELYKAVPDALCFMHHEDAQARGLRRGDEVLISNSRGEVRVRVETRGRNKPPKGLVFVPFFDARILVNKLILDATDPLSKQTDFKKCPVKITKVA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: GLMM_STAA2
Sequence: MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RL2_RHOP5
Sequence: MALKKYNPTTPGQRQLVMVDRSALYKGKPVKVLTEGKHSNGGRNNTGRITVRFRGGGHKKTYRIVDFKRTKVDVPAKVERLEYDPNRTAFIALIKYADGEQAYILAPQRLAVGDTVIAGAYVDVKPGNVMPLGNMPIGTIVHNVEMKIGKGGQIARSAGTYAQLVGRDHDYVIVRLNSGEQRLIHGRCTATIGAVSNPDHMNISIGKAGRTRWLGWRPHNRGVVMNPIDHPHGGGEGRTSGGRHPVTPWGKPTKGKKTRSNKSTNKFILISRHKRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SUFE_SHISS
Sequence: MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLTELRDEDRSPQNSIQGCQSQVWIVMRQNAHGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVSFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATL2_HUMAN
Sequence: MELSYQTLKFTHQAREACEMRTEARRKNLLILISHYLTQEGYIDTANALEQETKLGLRRFEVCDNIDLETILMEYESYYFVKFQKYPKIVKKSSDTAENNLPQRSRGKTRRMMNDSCQNLPKINQQRPRSKTTAGKTGDTKSLNKEHPNQEVVDNTRLESANFGLHISRIRKDSGEENAHPRRGQIIDFQGLLTDAIKGATSELALNTFDHNPDPSERLLKPLSAFIGMNSEMRELAAVVSRDIYLHNPNIKWNDIIGLDAAKQLVKEAVVYPIRYPQLFTGILSPWKGLLLYGPPGTGKTLLAKAVATECKTTFFNISASTIVSKWRGDSEKLVRVLFELARYHAPSTIFLDELESVMSQRGTASGGEHEGSLRMKTELLVQMDGLARSEDLVFVLAASNLPWELDCAMLRRLEKRILVDLPSREARQAMIYHWLPPVSKSRALELHTELEYSVLSQETEGYSGSDIKLVCREAAMRPVRKIFDALENHQSESSDLPRIQLDIVTTADFLDVLTHTKPSAKNLAQRYSDWQREFESV
What is the function of this protein?
Severs microtubules in vitro in an ATP-dependent manner.  This activity may promote rapid reorganization of cellular microtubule arrays.
What are the official names of this protein?
Katanin p60 ATPase-containing subunit A-like 2, Katanin p60 subunit A-like 2, p60 katanin-like 2.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.
Protein: SYP_SALEP
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLVRNELSSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSRIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGEDDIVFSDVSDYAANIELAEAIAPQTPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVKDSKSPLVALLVRGDHELNEVKAEKLPHVASPLTFATEEEIRAVINAGPGSLGPVNMPIPVIIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPVVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNFDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLMDDRKERPGVMFADMELIGIPHTIVIGDRNLDNDDIEYKYRRSGEKSLIKTGDIVDYLVKAIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_GEOSW
Sequence: MGIITNIAVQTKNPERFNVSIQKENGETLVFSVDQDVLLQFRLKKGMKIDEHSFQQIVYADEVKKTYHQALYFLSYRMRSEQEVVDYLKKKGASESIIDDVLHKLRENKYVDDREFAFAYVRTQKQTTAKGPYVIRKELEKLGVAEEWIEQSLAIYSFDEQVETAKSLYEKAKKQRAKQSLRQWKYQIGQLLYRKGFPQEVIDRVLLSERDEKEEQEWEALEYQGRKAHRRYEKYNSPMYEQKMKQALYRKGFPLEMIEQFLDKLKEGDKR
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTE_SHEAM
Sequence: MLNLLQGCKDFLHLTLSNPEHLDPIAPQPLYGHTLVSLWDTGVLVFEPVDGNSHKDIVLSSGVHGNETAPIELCNGLIQDVLEGRLQVKERVLFLIGNPAAINNGTRIVDENMNRLFSGEHSRGPGLSNPERVRAKKLETYVTRFFEKGAEKGEGRQRIHYDLHTAIRGSKHEKFAIYPYRPGRAFSGEQIMFLAASGVDTVLFHHEPTTTFSYFSSELFRADAFTIELGKVYPMGQNDMSKFANTREMFKRLICAEPLELAPFDETQVNLYQVCRVINKEVDDFEFTFSTDVENFSAFPRGHVIARQGGKDILVEQEAEAVVFPNAKVPVGQRTVIMLVPAVNPHVE
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: RS13_CLOBB
Sequence: MARIAGVDLPREKRVEIALTYIYGIGLSTSQKILSTTGISPDARVKDLSEDEVNEIRTYINKNLMVEGDLRRDVALNIKRLVEIGSYRGIRHRRGLPVRGQKTKTNARTRKGPKKTMANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: UBIA_BURO1
Sequence: MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPRWPLLVIFTLGTLLMRSAGCAMNDYADRDFDRHVKRTADRPLTSGKIRAWEAVAIAVGLSFIAFLLILPLNTLTKELSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMLAWVMLVANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAATLGIYVWIGVTLGFGLAYWVGWAAAVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGN
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
Protein: RBD2_GIBZE
Sequence: MRPRLQNFNALRARSYLTRLPLFTRLIVLAIIALSIASLQSVWNLREWGALIPEEISITNAYRLSTFPLIHLNVIHAILNLLALTPLMERFETEHGTLTSLALFFGPLTSIPAVAYVLIERCIFRANHGVLGASMWVFTLLAMESIQTYKSNPHFVIGSVNIPTWTTPLIMSLVVAALIPGTSLLGHLCGIAIGYVAGFGYAKLLAPPEWGLRWVENRLNLLKILPHYVSIDKTTYGRFGVLPTTNRPGPSGSAATELVGTTQRLGP
What is the function of this protein?
Probable serine protease.
What are the official names of this protein?
Rhomboid protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Protein: U390_ASPFU
Sequence: MAQGPLKKTKPSTAKRPTALAPKRGPRQIAPKKATLIKQQKITKKLTAGLTAKTERTLAQRAGHLELLAGGKKDKKAEKEKGKEKGGKKN
What are the official names of this protein?
UPF0390 protein AFUA_1G03640.
What is the protein family that this protein belongs to?
Belongs to the UPF0390 family.
Protein: Y1074_BRUMB
Sequence: MSDKTPRKPTAFRLEQPARVSAASEQEEPRRPRAVKDLEQITPQADVFDLTDDEAAELEILDPAFEAPERKGWSLSRILFGALGILVSFAIGIWTEDLIRALFARADWLGWTALGVAMVALAAFAAIILRELVALRRLASVQHLRKDAADAAERDDMAAARKAVDALRTIAAGIPETAKGRQLLESLTDDIIDGRDLIRLAETEILRPLDREARTLVLNASKRVSIVTAISPRALVDIGYVIFESARLIRRLSQLYGGRPGTLGFIKFARRVIAHLAVTGTIAMGDSVMQQLVGHGLASRLSAKLGEGVVNGLMTARIGIAAMDVVRPFPFNAEKRPGIGDFIGDLARLNSDRNARK
What are the official names of this protein?
UPF0283 membrane protein BMEA_A1074.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROA_STRP7
Sequence: MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILRGEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVLAGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHYELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQGPQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKLEITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAEELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAIAALLVADGEVELDRAEAINTSYPSFFDDLESLIHG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_BORBU
Sequence: MQFEVKDLINKIKKDGLEEAERASNDIILKAKREAEEIVARAEEAARVLKAKSEKEANDYKCHALEASRQAIRDLIIGVEKNLKSLFENALKDNVTEVLSDNNFLAELIIKITDSWAKGEKLVIQLNESDFSSLEQILRLKLGNKLKEGMELRPFRGISKGFKIQKKNIGLHYDFSAETIADILFDYLNPRFKEVIKVV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: VF165_ASFM2
Sequence: MANPSKRIINKKSKQASISSILNFFFFYIMEYFVAVDNETSLGVFTSMEQCEETMKQYPGLHYVVFKYMCPADAENTDVVYLIPSLTLHTPMFVDHCPNRTKQARHVLKKINLVFEEESIENWKVSVNTVFPHVHNRLTAPKLSIDEANEAVEKFLIQAGRLMSL
What are the official names of this protein?
Uncharacterized protein F165R, pF165R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus F165R family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: GMHA_PECAS
Sequence: MYQDLIRSELKEAAETLNNFLSDDANIQSIQNAAVLLANAFKAGGKVISCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDPSHLSCVSNDFGYDFVFSRYVESLGREGDVLLGISTSGNSGNIIKAIAAAKAKGMKVITLTGKDGGKMAGSADVEIRVPHFGYADRIQEIHIKAIHILIQLIEKEMADQ
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPP5_RABIT
Sequence: KASYIHLRGSDLRPQFHQFTAVPHPNVKPMAYANALLQLGVM
What is the function of this protein?
Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT (PubMed:9000529).  Implicated in wide ranging cellular processes, including apoptosis, differentiation, DNA damage response, cell survival, regulation of ion channels or circadian rhythms, in response to steroid and thyroid hormones, calcium, fatty acids, TGF-beta as well as oxidative and genotoxic stresses.  Participates in the control of DNA damage response mechanisms such as checkpoint activation and DNA damage repair through, for instance, the regulation ATM/ATR-signaling and dephosphorylation of PRKDC and TP53BP1.  Inhibits ASK1/MAP3K5-mediated apoptosis induced by oxidative stress (By similarity).  Plays a positive role in adipogenesis, mainly through the dephosphorylation and activation of PPARG transactivation function.  Also dephosphorylates and inhibits the anti-adipogenic effect of NR3C1 (By similarity).  Regulates the circadian rhythms, through the dephosphorylation and activation of CSNK1E.  May modulate TGF-beta signaling pathway by the regulation of SMAD3 phosphorylation and protein expression levels.  Dephosphorylates and may play a role in the regulation of TAU/MAPT (By similarity).  Through their dephosphorylation, may play a role in the regulation of ions channels such as KCNH2 (By similarity).  Dephosphorylate FNIP1, disrupting interaction with HSP90AA1/Hsp90 (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 5, PP5, Protein phosphatase T, PPT.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Note=Predominantly nuclear. But also present in the cytoplasm. Translocates from the cytoplasm to the plasma membrane in a RAC1-dependent manner.
Protein: EFTS_GLOC7
Sequence: MAEITAKLVKELREKTGAGMMDCKKALGESGGDMEKATEWLRQKGITSAEKKSGRITAEGLIHSYIHTGGRIGVLVELNCETDFVARGDTFKDLVNNIAMQIAACPNVEYVRVEDIPEAVAQKEKEIEKGRDDLAGKPENIKDKIVEGRIGKRLKELSLMDQPYIKDQSITVAELIKQTIAQIGENIQVRRFVRFVLGEGIEKEEKNFAEEVAAQTGQKVEQPQAAQETAKVEPPTPETVEEVEPPVTPPAQETDSPAAETTTEPPKTTPVDKPKGSPSKKGKKKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_MICLC
Sequence: MTVFSLVASHHDLDLDTVARLSAGATGVGPALPGSGAAGAVVLATCNRVEIYAEADGAGVEAARAGLLSAVAASTSLPDEDVHAAFRTLDADATARHLFEVGVGLDSAVVGEREIAGQVRRALTAAQEAGTASGPLVRLFESATRTAKDVGSHTALGAAGRSVVSVALDLAEELRGLTDAAAQRDFWAGATILLIGTGAYAGTTLAQLADRGATTVGVHSASGRAEQFVADRGGWALALGGEAVAGAVAEADVIIGSSGGERQISPERLQELREGGRRPLTVVDLALSRDFDPAVADLPDVDLITLESVRLAAPEQAQVAVAEARALVDDAVEEYRAAQRGRSADAAIKALRRHTLGVLDRELERVRARHGCTAAAEEVEFALRRMVNQLLHEPSVRAKRLAAEGRLDRYEDALEAVFGIEAPGRPASEVGTVEAACPAHEDEGGAARIA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: BIOB_LEPBP
Sequence: MIAEVQEKTISSSPSIISEEEALQILKGEVPLLPVVAKASEERFRHFGNRVRIHILDNIKNGYCPEDCGYCAQRKGGESGIQEYSLKSPEEIWEDAKKAKENGAYRFCMVTSGRGPTDKAVDKLAETISKINGELGMKVCLSAGILDGKKAKTLKDAGLDRYNHNLNTSESKYNEICSTHTFKDRLTTLEAAKEAEIGLCSGIIVGMGEELKDIVQVAFELKRLGVISIPVNFFIPIKGHAIQKSTLTPEFCVRVLSVFRLVNPDSEIRVGAGREGHLGFLQSMALYVANSLFAEGYLNVKGSEMEQTMNLIRDCNMVPEFTEGIPEGWEDYDSKFLYDEKNFPELYKHKK
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ATPA_PSEPG
Sequence: MQQLNPSEISEIIKGRIDNLDVSSQARNEGTVVSVSDGIVRIHGLADVMYGEMIEFPGGVYGMALNLEQDSVGAVILGAYDTLAEGMSAKCTGRILEVPVGKELLGRVVDALGNPIDGKGPLGNTQTDAVEKVAPGVIWRKSVDQPVQTGYKSVDAMIPVGRGQRELIIGDRQIGKTAMAIDAIINQKDSGIFCVYVAVGQKRSTVANIVRKLEENGALANTIVVVASASESAALQFLAPYAGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVSEEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESAMFNSGIRPAVNAGVSVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDEATRKQLEHGQRVTELMKQKQYAPMSIADMALSLYAAERGFLTDVEVSKIGSFEQALIAFFNRDHAELMAKINVKGDFNDEIDAGLKAGIEKFKATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLMM_LEGPH
Sequence: MSQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLESALEAGLSAAGVDVALLGPMPTPGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGKLPDSVELAIEAQLEKQLQTVPSAKLGKATRINDAAGRYIEFCKSTIPSLSRLSNLKIVVDCANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGLDGDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVPFQRSKVGDRYVLETLREKDWKIGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALHELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKHLNGEGRVLLRPSGTEPLLRVMVEGANASIVKQQAQMLCDDISQIDKKMTESLPST
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RL5_RICB8
Sequence: MLRFKELYQKEIISNLQKEFSYKNKHEIPAIEKIVINMGVGEAIADSKVIDKAVNDLTLISGQKPFVTSARKSIATFKLRDGMKIGCKVTLRKDRMYDFLERLVIVALPRVKEFRGFSYKSFDGKGNFTFGLKEQIVFPEINYDKIDSIRGMDITIVTSAKTDKEGKSLLSGFNLPFYN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: COX1_CRANE
Sequence: MFINRWLFSTNHKDIGTLYMIFGAWAGMVGTGLSILIRAELGQPGSLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLSSSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAITQYQTPLFVWSVMITAILLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTIGGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFTGYTLNDTWAKIHFTIMFVGVNMTFFPQHFLGLAGMPRRYSDYPDAYTTWNTISSMGSFISLTAVILMVFIIWEALASKRVVKSIPLTSTNLEWMHGCPPPFHTFEEPAFIKSSNK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: U2AF2_SCHPO
Sequence: MDLSSRLSSGSSRIPKRHRDYRDEEPRRERGSGGIGREDPRGHYGSERPRRRRRDESDFRRHRESRERSYREDERPRRERRYDDYEPRSLRYSSVGRSRSPPPSRERSVRSIEQELEQLRDVTPINQWKRKRSLWDIKPPGYELVTADQAKMSGVFPLPGAPRAAVTDPEKLLEFARSAEGSIIAPPPPLQPGASRQARRLVVTGIPNEFVEDAFVSFIEDLFISTTYHKPETKHFSSVNVCKEENFAILEVATPEDATFLWGLQSESYSNDVFLKFQRIQNYIVPQITPEVSQKRSDDYAKNDVLDSKDKIYISNLPLNLGEDQVVELLKPFGDLLSFQLIKNIADGSSKGFCFCEFKNPSDAEVAISGLDGKDTYGNKLHAQFACVGLNQAMIDKSNGMAILTELAKASSQSIPTRVLQLHNLITGDEIMDVQEYEDIYESVKTQFSNYGPLIDIKIPRSIGTRNSGLGTGKVFVRYSDIRSAEVAMEEMKGCKFNDRTIVIAFYGEDCYKANAW
What is the function of this protein?
Necessary for the splicing of pre-mRNA.  The SF1-U2AF59-U2AF23 complex has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
What are the official names of this protein?
Splicing factor U2AF 59 kDa subunit, U2 auxiliary factor 59 kDa subunit, U2AF59, U2 snRNP auxiliary factor large subunit.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.