PharMolix/UniProtQA huggingface dataset:
Protein: DAPE_BUCAP
Sequence: MVCSITKLAQKLISIPSISPKDLGCQDIMIDFLDNLGFEIKKININDTKNFWATRGFGKTLTFAGHTDVVPPGDYKYWNDDPFNPVIKNGLLFGRGSSDMKGALASMLIASERFIKKNPNYEGRLSFLITSDEESSAIDGTKKVIDYLISRKDTIDYCVIGEPCSSSKIGDVIKNGRRGSITANLTIHGIQGHIAYPHLADNPIHKGLPIILKILSIKLDDGNAFFAPTSVNISNIHAGDGINNIIPGSLFVQFNFRFSTETSEKEIKSKFTQILDNNNINYSLNWFFSGNPFITKKGLLIDNITKSIINLNKVKPVLSTDGGTSDGRFIASMNAEIVELGLMNNTIHKSNEYVRISDLEKLAIIYEDIMYRLLT
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MINC_ECOLU
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLKHAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGKEKAPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARLQLVENALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: HLDE_HAES1
Sequence: MQYSAQFNRAKVLVLGDVMLDRYWFGATNRISPEAPVPVVRVQENEERAGGAANVAMNIASLNVPVRLLGLTGKDEAARALMQLLEKQSIHCDFTQLDSHPTITKLRILSRHQQLLRLDFEEDFNNITSADLLRKLESAVQNYGALILSDYGKGTLNDVQKMIQIARKVNIPVLIDPKGTDFARYRSATLLTPNMSEFEAVVGKCHSEEEIAEKGLQLIKDLDLSALLVTRSEKGMTLLRPNNAPFHLPTEAKEVFDVTGAGDTVISVLATALADGRSYEEACYLANVAAGIVVGKLGTSTVSTVELENAIHGRTTAGFGIMEESQLKAAVELAKARGEKIVMTNGCFDILHPGHVSYLENARKLGDRLIVAVNTDNSVKRLKGETRPINDLATRMAVLAGLSSVDWLVAFDEDTPQRLIAEILPDLLVKGGDYKPEEIVGSKEVWLNGGEVKVLNFENGCSTTNVIKKIQQLKE
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: FENR2_PEA
Sequence: MSHLAVSQMAVTVPVSSDFSVRRSAFKSSNLNFRDKSWAPVFTLGMKAKNCGWRNHNVICMSVQQASVPKVTVSPLELENPSEPPLNLHKPKEPYTATIVSVERLVGPKAPGETCHIVINHDGNVPYWEGQSYGVIPPGENPKKPGSPHNVRLYSIASTRYGDNFDGKTASLCVRRAVYYDPVTGKEDPSKNGVCSNFLCDSKPGDKIKIAGPSGKIMLLPEDDPNATHIMIATGTGVAPYRGYLRRMFMESVPTFKFGGLAWLFLGVANVDSLLYDDEFTKYLKDYPDNFRYNRALSREEKNKNGGKMYVQDKIEEYSDEIFKLLDNGAHIYFCGLRGMMPGIQETLKRVAEKRGESWEEKLSQLKKNKQWHVEVY
What is the function of this protein?
May play a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power.  Is involved in nitrate assimilation.
What are the official names of this protein?
Ferredoxin--NADP reductase, root isozyme, chloroplastic, FNR.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PURU_BACSU
Sequence: MKSYMTQRLDEYRDGNEDKGRLLVSCPDQPGIVSAVSAFLFEHGANIIESNQYTTDPEGGRFFLRIEFDCAGIREKKSSLQAAFASVAEKFDMTWSLTLASELKRVAIFVSKELHCLHELIWEWQTGNLMAEIAVVISNHEEARELVERLNIPFHYMKANKDIRAEVEKKQLELLEQYDVDVIVLARYMQILTPDFVSAHPNRIINIHHSFLPAFIGANPYKRAYERGVKLIGATSHYVTNDLDEGPIIEQDIERVDHRDNAEALKNIGRTIERSVLARAVKWHLEDRVIVHENKTIVFN
What is the function of this protein?
Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
What are the official names of this protein?
Formyltetrahydrofolate deformylase, Formyl-FH(4) hydrolase.
What is the protein family that this protein belongs to?
Belongs to the PurU family.
Protein: PDXH_RHILO
Sequence: MSDTELTTSDFTEAAEPFRLFAAWLDDATKSEINDANGVALATVDAEGMPDVRMVLLKGFDEGGFVFYTNFESAKGQEILGSMKAAMCFHWKSLRRQVRIRGPVEIVSDAEADAYYATRPRGSRIGAWASKQSRPLESRFALEKAVAEYTARYAIGEIPRPKHWSGFRIVPKTIEFWHDRPFRLHDRVVFSRNAKGDWDKARLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: YFFR_ECOLI
Sequence: MKVLGNILWWAFVGFMAYATLIKPDNTDPAVVNYEEPLPMELANYGEPGEGAKIMNAAKIMGRDYAWKHVKEDRLPCLFAAGVVADNILVKYHFSNETEFKLKAAAVRECANVAENNGFVLVGRVFEKRN
What are the official names of this protein?
Uncharacterized protein YffR.
Protein: KR204_HUMAN
Sequence: MSYYSHLSGGLGCGLAVAVTMGRTVAVAEYGRCRHGCHSSYSAR
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity).
What are the official names of this protein?
Putative keratin-associated protein 20-4.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 20 family.
Protein: TRMB_SHIDS
Sequence: MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPVMGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLHVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDLMFERVK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: FLGI_SALPK
Sequence: MFKALAGIVLALVATLAHAERIRDLTSVQGVRENSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASYPPFARQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAIIERELPTQFGAGNTINLQLNDEDFTMAQQITDAINRARGYGSATALDARTVQVRVPSGNSSQVRFLADIQNMEVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQLNVNQPNTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSANLNSVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: PIANP_MOUSE
Sequence: MWSAQLLSQLLPLWPLLLLSVLPPAQGSSHRSPPAPARPPCVRGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVVPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSVNPGFLPLDYGFAAPHGLATPHPNSDSMRDDGDGLILGETPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLGAFGDSPTPTPDHEEPRGGPRPGMPQPKGAPAFQLNRIPLVNL
What is the function of this protein?
Acts as a ligand for PILRA in neuronal tissues, where it may be involved in immune regulation.
What are the official names of this protein?
PILR alpha-associated neural protein, Brain protein 1, PILR-associating neural protein, Paired immunoglobin-like type 2 receptor-associating neural protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PSBC_CYCTA
Sequence: MKTLYSLRRFYPVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVVDTFPYFVSGVLHLISSAVLGFGGIYHALIGPETLEESLPFFGYVWKDRSKMTTILGIHLILLGVGAFLLVLKALYFGGVYDTWAPGGGDVRKITNLTLSPSVIFGYLLESPFGGEGWIVSVDNLEDIIGGHVWLGSICIFGGIWHILTKPFAWARRAFVWSGEAYLSYSLGALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEIIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMNPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: COX16_YARLI
Sequence: MLEQNKFKTKKQQQAWNKTLAGRYYNAMVKRPFLFFGLPFLTTIYAASVYFAEFTAYRYEIQDGKVKALSEEEALKLDKGRRKVDMKEEFYRLQQLGKQDDWEQVRVPRMKGESDNVF
What is the function of this protein?
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.  May participate in merging the COX1 and COX2 assembly lines.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PLSB_MYCMM
Sequence: MTKPVADTSAVLTSEDTLVLASMGSPVEMQLIMDWLGEQRARTPGAKFDVLKLPPRNAPTAALTALVEQLESGSEAGADRSIVPVQVFWQPPADRSRLAKVAGLLPGRDPYHPNPRQQRRILRSDPQRARVMAGESATVSELRKQWRDNTVGEDQHDFAHFVARRAILALARAEYRILGPQYKSPRLVKPEMLASARFRAGLEKIPGATVEEAGKMLDELATGWSQASVDVFSVLGRLISRGFDPEFDYDEYQVAAMRTALEAHPAVLLFSHRSYIDGAVVPVAMQDNRLPPVHMFGGVNLSFGVMGPLMRRAGMIFIRRNIAGDPLYKYVLKEYVGYVVEKRFNLSWSIEGTRSRTGKMLPPKLGLMSYVADAYLDGRSDDILLQGVSICFDQLHEIAEYAAYARGAEKTPEGFSWLYNFIKAQGERNYGKIYVRFPEAVSMRQYLGVPHGPITHDLAAKRLALQKMSFEVAWRILRATPMTATGLVCALLLTARGTALTLGQLHHTLQDSLDYLERKQTPMSTSALRLRSREGVRAAVDALSNAHPVTRVDSGREPVWYIAPEDELAAAFYRNSVIHAFLETSIVELALAHARHAEGDRMAAFWDQVMRLRDLLKFDFYFADSAAFRANIAEEMAWHRDWESQVAAGGDQIDAILYAKRPLISDAMLRVFFEAYAIVADVLRDAPANIKQKDLTDLALGLGRQYVAQARVRSSEPVSTLLFATARQVVDDQHLIEPAPDLTERRSAFLAELRNILRDFDYVGKIARNRFVARELKARQERLEQQAQ
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NVD2_CIOIN
Sequence: MLIEYLIRITVMVITSERLLILMGLCDESFHFPVMIRVVFNAAVAIVIALVMSKLYKVLFAPLDLRRKLEDVGYVHHDHSVSREENIRDTQRRKKLGNTPPVFPNGWFKVADSTWIKKGQVKSIYFFGEQLALFRNKRGLLRALDAYCPHLLANMAAGGKVVNSDCLECPFHGWKFSGETGKLVDVPYAQKVPTFVSVKKWSCCEVDGMAYLWYHCDGGEPKWVLPSSVTINTLKYAGKTEHIINSHIQDIPENAADISHLDHLHKPVIGSDVEKTNESLLNNLIFHSIQASWKPPTDPNEPHRSTMSIKDNIHLSIFNIKIPLLYLEFEIDQIGPGAVHIHVRTPFFRGLMLQNVTPIEPFVQKLTHSFYVSPWVPVCIAKAFYLLETTQIERDILMWNNKTYFRQPVLVKEESALAKHRRWYQQFYSENSPRMNHRGDLVYPGKPKLADW
What is the function of this protein?
Catalyzes the production of 7-dehydrocholesterol (7-DHC or cholesta-5,7-dien-3beta-ol) by inserting a double bond (desaturating) at the C7-C8 single bond of cholesterol.  Essential regulator of steroid biosynthesis as this reaction is the first step in the synthesis of the steroid hormone Delta(7)-dafachronic acid.
What are the official names of this protein?
Cholesterol 7-desaturase nvd 2, Neverland 2, Nvd-Ci-2.
What is the protein family that this protein belongs to?
Belongs to the cholesterol 7-desaturase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VE7_HPV56
Sequence: MHGKVPTLQDVVLELTPQTEIDLQCNEQLDSSEDEDEDEVDHLQERPQQARQAKQHTCYLIHVPCCECKFVVQLDIQSTKEDLRVVQQLLMGALTVTCPLCASSN
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: PSBE_TUPAK
Sequence: MAGTTGERPFSDILTSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGTPRPNEYFTEDRQEAPLITDRFNSLEQVKKLSNIR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TMA7_CAEBR
Sequence: MSGRQGGKAKPLKAPKKGEKDLSEEDVEFKKKQQEEAKKIKEMAAKAGQRGPLLGGGIKKSGKK
What are the official names of this protein?
Translation machinery-associated protein 7 homolog, Coiled-coil domain-containing protein 72 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMA7 family.
Protein: HIS6_PSEAB
Sequence: MALAKRIIPCLDVDNGRVVKGVKFENIRDAGDPVEIARRYDEQGADEITFLDITASVDGRDTTLHTVERMASQVFIPLTVGGGVRSVQDIRNLLNAGADKVSINTAAVFNPEFVGEAADRFGSQCIVVAIDAKKVSAPGEAPRWEIFTHGGRKPTGLDAVLWAKKMEDLGAGEILLTSMDQDGVKSGYDLGVTRAISEAVNVPVIASGGVGNLEHLAAGILEGKADAVLAASIFHFGEYTVPEAKAYLASRGIVVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_PELPD
Sequence: MELNDKKVLVVGLAKTGVACARFLASRGARVTVTDMRDEAALAGQLALLEGRGIRRELTRHDAGTFTQSHLIVVSPGVPRTLPQLVMAHEAGVEIISEIELASRFIQAPLVAITGTNGKTTATTITGDIFIKNGFRTFVGGNIGNPLIELLESAEPVERVVAEISSFQLEWIRAFRPAVAALLNLSEDHLDRYASYREYIEAKLRIFENQTADDYAVVNADDELVMEHSRGLRACLFPFSRKQELDEGIFHREGLIVWRHNGREERFPTAGFRLQGVHNLENIMAALACSLLLECRPTESLACVREFEALHHRMEFVRELNGVRWYEDSKATNVGSVEKALESFDAITLIAGGKDKGGSYSPLSRLVRERVRHLVLIGEAAGRMQEELGTLTDTRRAATLEEAVSLAAELTAPGGTVLMSPACSSFDMFRDYEERAQRYIAAVKAL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_METFK
Sequence: MTFRILGIDPGLRLTGFGVIEKTGEKLAYVASGTIKTTTGKGSEIEDLPTRLKIILDSLAEVIDNYQPQQAAIEKVFVNVNPQSTLLLGQARGAAISALVLQGLPIAEYTALQVKQSVVGHGHAAKDQVQEMVKRLLNLPGLPRPDSADALACAICHAHGGQGLGKLATAGFRVKGGRLI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MOAA_NITWN
Sequence: MTGCSAPAETSGSRKMVDPFGRNISYLRVSVTDRCDLRCFYCMSEDMTFLPKADLLTLEELDRLCSAFIAKGVRKLRLTGGEPLVRRNVMSLIRSLSRHLQSGALKELTLTTNGSQLVRFANELKDCGVKRINVSLDTLDPARFREITRWGDIQKVMAGIDAAQAAGLAVKINAVALKNLNEDEIPSLMEWAHSRDMALTLIEVMPMGDIGASRADQYLPLSMLRARLEGQYTLTDLDDSTGGPARYVRVSETGGKLGFITPMTHNFCESCNRVRITCTGTLHTCLGHEDASDLRRPLRASPTDELLYETIDRAIGLKPKGHDFIIDRHNRPSVSRHMSVTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: CIRBP_HUMAN
Sequence: MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSSGGSYRDSYDSYATHNE
What is the function of this protein?
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival.  Acts as a translational activator.  Seems to play an essential role in cold-induced suppression of cell proliferation.  Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.  Acts as a translational repressor (By similarity).  Promotes assembly of stress granules (SGs), when overexpressed.
What are the official names of this protein?
Cold-inducible RNA-binding protein, A18 hnRNP, Glycine-rich RNA-binding protein CIRP.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Translocates from the nucleus to the cytoplasm after exposure to UV radiation. Translocates from the nucleus to the cytoplasm into stress granules upon various cytoplasmic stresses, such as osmotic and heat shocks. Its recruitment into stress granules occurs in the absence of TIAR proteins (By similarity).
Protein: CO9_BOVIN
Sequence: MSAGQRFAFAICILEISLLRAGPTPSYDPAERQGTPLPIDCRMSSWSEWSKCDPCLKQMFRSRSIEIFGQFNGRKCVDAVGDRQQCVPTEACEDPEEGCGNDFQCGTGRCIKNRLLCNEDNDCGDYSDEDNCEQDPRPPCRNRVVEESELARTAGFGINILGMDPLSTPFDNQYYNGLCDRVWDGNTLTYYRRPWNVASLTYDTKADKNFRTENHEESIQILRTIIEEKKLNFNAGLSVKYTPVEAIEKNKCVDLEHSDKGSTSSPSKLAAEAKFRFTYSKDDIYRLLSSYSAKQEKMFLHVKGKVHLGRFVMRSRDVMLQTTFLDSINTLPTTYEKGEYFAFLETYGTHYSSSGSLGGLYELIYVLDKKSMEQKDIELRDVQRCLGFDLDLSLKVGVEVTGNFDSKLCSKKGMGQTETNPEADLFDDVITFIRGGTRKYATELKEKLLRGARMINVTDFVNWAASLNHAPVLISQKLVPIYDLIPVKMKDAHLKKQNLERAIEDYINEFSVRKCQPCQNGGTVVLLDGECVCSCPKEFKGVACEIKK
What is the function of this protein?
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.  C9 is the pore-forming subunit of the MAC.
What are the official names of this protein?
Complement component C9.
What is the protein family that this protein belongs to?
Belongs to the complement C6/C7/C8/C9 family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore.
Protein: Y996_LATSS
Sequence: MKQSFYRYLMTQRDPNNYEPVAQFANNAFFDQSFPKHEGDYELLSQYLELNGSYLPSMLIFDEAYQLYQESEQA
What are the official names of this protein?
UPF0346 protein LCA_0996.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: TAUB1_PARXL
Sequence: MSGLEIRQLQVAYEGARGAAPHVALADVDLRIEPGEFVVALGASGCGKTTLLNCIAGFIQPTEGEVRLNGEPVLGPGADRGVVFQKYALMPWLDVLDNVALGLRFQRVPKAERERIALEMLKLVGLEKHARSQVYALSGGMQQRVGIARALASDPQVLLMDEPMGALDAMTRESMQELVLDVWGRTRKTVFFITHSVEEALFLATRLVVMTPGPGRIADSYDLPFAQRFLQTRDARAVKSSADFIEWRERLVRRLHERNQEEVVS
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLPK_CLOB1
Sequence: MEKYIMSLDQGTTSSRCIIFNKKGEIVSVAQKEFTQIYPKAGWVEHDPLEIWGKQAGVAGEALNIARISPEQIAGIGITNQRETTVVWNKRTGMPVYNAIVWQCRRTAGYCDELREKGIDKTIKEKTGLMLDAYFSATKIKWILDNVEGARELAEKGDLLFGNIDTWLIWNMTKGKIHVTDYTNASRTMLFNIHELKWDEELLEILDIPKSMLPEVKPSSCVYGETDEILFGVSIPIAGDAGDQQAALFGQTCFNAGMAKNTYGTGCFLLMNTGEKAVDSKNGLLTTIAVGIDGKVEYALEGSIFIGGAVIQWLRDELRMVKTAQETEKYATEVEDNNGVYLVPAFVGIGAPYWDSYARGTILGLTRGAKKEHIIRAALESMAYQTHDVLKAMEEDSGIELKALKVDGGACQNNFLMQFQSDILGVEVDRPEVVETTALGAAYLAGLAVGYWKDRNEISQNWAISRSFAPAMEDEKKEKLIKGWHKAVTKAMDWEERE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RL36_ACIET
Sequence: MRVSASVKKICRNCKIIRRKGVVRVICTDQRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CH10_PSEP1
Sequence: MKLRPLHDRVVIRRSEEESKTAGGIVLPGSAAEKPNRGEVVAVGTGRVLDNGEVRALAVKVGDKVVFGPYSGSNTVKVDGEDLLVMAENEILAVVEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.