PharMolix/UniProtQA huggingface dataset:
Protein: NCAP_VHSV0
Sequence: MEGGIRAAFSGLNDVRIDPTGGEGRVLVPGEVELIVYVGEFGEEDRKVIVDALSALGGPQTVQALSVLLSYVLQGNTQEDLETKCKVLTDMGFKVTQAVRATSIEAGIMMPMRELALTVNDDNLMEIVKGTLMTCSLLTKYSVDKMIKYITKKLGELADTQGVGELQHFTADKAAIRKLAGCVRPGQKITKALYAFILTEIADPTTQSRVPSMGALRLNGTGMTMIGLFTQAANNLGIAPAKLLEDLCMESLVESARRIIQLMRQVSEAKSIQERYAIMMSRMLGESYYKSYGLNDNSKISYILSQISGKYAVDSLEGLEGIKVTEKFREFAELVAEVLVDKYERIGEDSTEVSDVIREAARQHARRTSAKPEPKARNFRSSTGRGREQETGESDDDDYPEDSD
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the novirhabdovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: LOLA_SHIF8
Sequence: MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ATP8_CANGA
Sequence: MPQLIPFYFMNQLTYGLLLITVLLILFSQFFLPMILRLYVSRLFISKL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: ATPF_COLP3
Sequence: MDINMTLVGQLIAFVVFVIFCMKYVWPPIIGAIEDRQATIADGLAASDRAAKDLELAQEKATAQLKEAKVQAASIVDAAKKHEAKIVDEAAGKAQVEKERILASGHAEIETERNRAKEELRKEVAVLAIAGAEKILERSIDAAAHSDILDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LEU3_CLOAB
Sequence: MKEYKVAVIPGDGIGVEIVGEALKVLEKVGAKYDTKFNFTEVKAGGCAIDEFGVPLPNETLEICKNSDAVLLGAVGGPKWDTLPGEKRPEKALMGLRGGLGLYANLRPAKVYDILKSASPLKEEIINKGVDLLVVRELTGGIYFGERGRDIQNGINSAYDTERYNVEEIKRIAHVAFKAALKRNKKVTSVDKANILESSRLWRETVTEVAKEYPEVELNYLYVDNAAMQLVREPSQFDVIVTSNIFGDILTDEASMVTGSIGMLPSASLRNDTFGMYEPIHGSAPDIAGQDLANPLAQILSVAMMLEYSFNMTEAARDVEDAVEKVLNSGYRTGDIYTEGSKKVGTKEMGKLVLAEL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOPH_CANAW
Sequence: MTTTAKTDDIPIDTVILDIEGTVCPITFVKDTLFPYFIEKLPSILDKFQYPLSNTSASSDDQVLNILKQLPDNITKSSESIYKHFKNLVDQDIKDPILKSLQGLIWKQGYENNELQAPIYQDSVEFIESFPTKSSTNNKIYIYSSGSIKAQILLFGHVKSTTTTTTTTTTITNEVIDLNPKLNGYFDITTAGFKNQSNSYKKILQEINKSSTPKSVLFLSDNINEVNAAIEAGMKSYIVIRPGNPPIDDDDDGNDDKINHKIIYSLDELDL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PFKA_VIBCH
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRTALGAGLEVFGIYDGYQGLYEDRIKQLDRSSVSDVINRGGTFLGSARFPQFREVEVREKAIENLKKHGIEALVVIGGDGSYMGAKKLTEMGFPCIGLPGTIDNDIAGTDYTIGYLTALNTVIEAIDRLRDTSSSHQRISIVEIMGRHCGDLTLTSAIAGGCEYIITPETGLNMEQLISNIKDGIAKGKKHAIIALTELMMDANKLAKEIESATGRETRATVLGHIQRGGKPTAFDRVLASRMGNYAVHLLMEGHGGRCVGIQKEQLVHHDIIDAIENMKRPVRTDLYKVAEELF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_COREF
Sequence: MKVTPDTPGRDDPGPGRRIGLDVGTVRIGVAASDRDARLAMPVETVPRETGMKGPDRGDIDRLIDIITEYDAVEVVVGLPRDLQGNGSASVKQAREIAFRIRRRLTATGREIPVRLGDERLTTVVATQALRASGINERDGRKVIDQAAAVEILQTWLDGRATALNTLPETPHTDEKGNFPR
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_STAMF
Sequence: MVEEEFMNEFLKKTGYQVYKCKKCGERFWSLVPRDTCPDRPCSKYDFLYNEYKGVPPLTFDEARRKFIEFFTSHGHGYVDPYPVLARWRNDLYLTIASIIVFQPAVTEGIVDPPYNPLVIVQPSVRLEDIDNVGLTFGRHLTSFEMGGHHAFNKKDQYVYWVNETLQYAFDFFTKIIGIEPENIVFKESWWEGGGNAGPAYEVLVDGLELATLVFMKYKIVNGKKVRNPVLVVDTGYGIERIAWFTQRTPTAFHTIFSSLLETYKNILGIDEPPYDVLKKIVYLLSDKEIEDVYMLNKYLEEIDYSEYYKSLVDTINLYTALDHVKTLSLMLSDGIVSSNTGEGYLARLVIRRLLRTLIRLGIKVSTLEDIVLELIDKQAKYWKGRYVYDKFHRRLDYILDVMSYETRKYIDIVTRGIREVDRFIKKKKKITFDDLIQIYDSKGIPPEIVVERAKHYGQEIRVPSNFYSLIAARHGGSQALIKEKEHELPDEIVEWASKHDPTKKLFHENPYLRRASAKVLDSLNEYVIFDQTIFYPRAGGQDHDKGYVILGNEHIPVKHVYKVGEVIVHQLATKRRLVPGTQVELVIDWYNRYRLMRHHTATHIVLGAARKVLGEHVWQAGAEKTVEKARLDITHYKSLSDEEIRKIEELANKVIDERIDLKFYFLPKFEAEKRFGLRIYQGGAVYSPILRIVEIPGWDAEACFGTHVYNTSEIGGIKIIKAEKIQDGVIRLEYIASTRLPEYISDLQKEVDKALKFLGAKGLPISIVAKKVSEELDKYKTLLIQYRRLFKEILLKHLLEEALEICGLKTVVIEKQLEDEQLYKSIIEDLSLKKRVLTIYVSDKFVEIAIHPDEANNRKLDLRKLVEILQNMGGRGGGKPDHIYIKIKEPKQIVKLIVEAITNLLCKA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB1_STRA5
Sequence: MTQPILQVSDLSVYYNKKKALKEVSMDFYPNEITALIGPSGSGKSTLLRAINRMGDLNPEVTLTGAVMYNGHNVYSPRTDTVELRKEIGMVFQQPNPFPMSVFENVVYGLRLKGIKDKATLDEAVETSLKGASIWDEVKDRLHDSALGLSGGQQQRVCIARTLATKPKIILLDEPTSALDPISAGKIEETLHGLKDQYTMLLVTRSMQQASRISDRTGFFLDGNLIEYGNTKEMFMNPKHKETEDYITGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PROF2_BETPN
Sequence: MSWQTYVDEHLMCDIDGQGQQLAASAIVGHDGSVWAQSSSFPQFKPQEITGIMKDFEEPGHLAPTGLHLGGIKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLIDQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Allergen Bet v II, Pollen allergen Bet v 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NU5C_PELHO
Sequence: MEHIYQYSWIMPFIPLPVPMLIGVGLLLFPTTTKHLRRIWAFPTLFLLGLVMLLSAYFFILQLNKSYIYQYVWSWTINNDFSLEFGHLVDPLTSIMSILITTVGITVLIYSEKYMFHDQGYLRFFSYMTLFHVSMLGLVTSSNLIQIYICWEFVGMFSYLLIGFWFTRPVAANACQKAFVTNRVGDFSFLLGILGLYWITGSFEFRDLFEIFYNLVHNNEIPFFFLTLCAFLLFGGALAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFIVMPYILNLISFIGIITVFLGATLALSQKDIKRGLAYSTMSQLGYMMLALGMGSYRAALFHLITHAYSKALLFLGAGSIIHSMEAFVGYSPEKSQNMVLMGGLIKHMPITKTSFLLGTLSLCGIPPLACFWSKDSILNDSWLYSPIFAIIACSTTGFTAFYMFRIYLLTFEGHLNVHFRNYSGKRSNSFYSISLWGNEGPKTLQKKKGFKTLLTMNNKKGVTFFCKKIDRIDSSVRNMTRLFTHFEAKNTLPYPHESDNTMLFPMVLLVLFTLFVGAIGIPFNQEDKNLDILSKFLTPSINLLHEKSNNSVDWYEFIPNATLSVSLSYFGIVIASVLYKPNYLSLTKLNLLNLFVKGGPNKIFGDRIRNRIYDWSYNRGYIDTFYAISLARGLRGFAEFTHFFDARVIDGITNGMGILSFFLGEGIKCVGGGRLSSYLLLYFDCVLLFLFISSFLYLFHF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RU17_DROME
Sequence: MTQYLPPNLLALFAAREPIPFMPPVDKLPHEKKSRGYLGVAKFMADFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDREREKKKKRSKSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEKYRPPPAHHNMFSVPPPPILGRGNASTNPNPDNGQQSSGDPSWWRQ
What is the function of this protein?
Mediates the splicing of pre-mRNA by binding to the stem loop I region of U1-snRNA (PubMed:15611175).  Required during oogenesis for nurse cell chromatin dispersal (PubMed:24244416).
What are the official names of this protein?
U1 small nuclear ribonucleoprotein 70 kDa, U1 snRNP 70 kDa, U1-70K, snRNP70.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm.
Protein: C80G2_COPJA
Sequence: MDLQIALFSLIPVILVFILLLKPKYKNLPPGPHPWPLIGNLPILFTNTEVPLHITLANMARTHGPIMILWLGTQPTVMASTAEAAMEILKTHDRIFSARHIRMSFRLKHHIKYSLVWSDCTDYWKLLRKIVRTEIFSPKMLQAQSHVREQKVAELIDFLRSKEGQVVKISQFVFGTLLNILGNVVFSKDVFVYGDETDKGGIQNLIREMLMIGAEPNVAEFYPSLEELDLQGLKKKCDERFIRVMKMWEGTVKERKANRNEESKDMLDVLLANDFNDAQINALFLETFGPGSETSSATIEWVIAELIKSPKEMAKVRKELNEVVGTSTIKESDLPQLPYLQACIKEAMRLHPAAPFLLPRRAAETCEVMGYTIPKNSQVLVNAYAIGRDPKSWKDPSTFWPERFLESDVDFHGAHYQFIPFGSGRRTCVGMPLATRTIPLIVGSLVHNYDFGLPGGNRPEDLKMNEMLSLTLAIDPSLCVVPKARA
What is the function of this protein?
Cytochrome P450 that catalyzes an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis.  Catalyzes the formation of (S)-corytuberine from (S)-reticuline, and also, with a lover efficiency, the 4'-O-demethylation of codamine to produce orientaline, and subsequent C-C-phenol coupling of orientaline.  Can also use (R,S)-norreticuline, (R,S)-orientaline, (S)-N-methylcoclaurine and (S)-coclaurine as substrates, but not (R,S)-6-O-methyllaudanosoline, (R,S)-6-O-methylnorlaudanosoline, (R,S)-laudanine, (R,S)-norlaudanine, (R,S)-4'-O-methyllaudanosoline, (R,S)-pseudocodamine, (R,S)-norpseudocodamine, (R,S)-laudanosine, (R,S)-norlaudanosine, (R,S)-laudanosoline or (R,S)-norlaudanosoline.
What are the official names of this protein?
Corytuberine synthase, Cytochrome P450 80G2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: GLMU_BRUME
Sequence: MTDRTCLSIVLAAGEGTRMKSNLPKVLHRVAGLPLVCHVVNAVRGTGKSDVALVVGRGAEDVRSAVEKIAGPVSAFEQKERLGTAHAVLAAREAIARGYDDLLIVFGDTPLIEAQSLLAARERLAQGADLVVIGFRPASPHGYGRLIEEGGQLVAIIEEKEATDEQKKIGFCNGGLMALRGQHALALLDAVGNDNAKGEYYLTDIVAIAHGKGLNVTAIEVPVDNVIGINNRAELAEAETIWQNRKRRELMLSGVTLIAPETVFFSYDTVIEPDVVIEPNVFFGPSVHVASGALIHSFSHLEGAQVGEKAEIGPFARLRPGADLAEKSKVGNFCEVKNAKVGKGAKINHLAYIGDAVIGASSNIGAGTITCNYDGYNKFKTIIGDNAFIGSNSSLVAPVEIGDNAYIASGSVITADVPADALALGRARQETKEGRAKILREKYAAIKAAKSVSK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_SALCH
Sequence: MSKLFWAMLAFISRLPVPSRWSQGLDFEQYSRGIVMFPFIGLILGGVSGLIFILLQSWCGIPLAALFCILALALLTGGFHLDGLADTCDGIFSARRRERMLEIMRDSRLGTHGGLALIFVLLTKILVVSELALRGTPMLAALAAACAAGRGSAVLLMYRHRYAREEGLGNVFIGKVSGRQTCITLGLAVIVATVLLPGMQGLAAMVVTCAAIFILGQLLKRTLGGQTGDTLGAAIELGELIFLLALL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASSY_HELHP
Sequence: MAAIKKVVLAYSGGLDTSVILKWLGDNYHCEVVTFTADIGQGEEVEPAREKALKLGIKSENIFIEDLREEFIKDFVFPMFRANTIYEGEYLLGTSIARPLIAKRLVEIAKSVGADAIAHGATGKGNDQVRFELGAYALNPDIKVIAPWREWDLNSREKLLAYAESAGIAIEKKQNKSPYSMDANLLHISYEGQILEDPNVEPEEDMWRWSVSPLNAPDKPESISIEFQNGDGVAINGEKLSPANFWVNLNELGGKHGIGRLDLVENRYVGMKSRGCYETPGGTIYLKAHRAIESLCLDREEAHLKDSIMPKYAELIYNGYWFSPEREALQALIDKTQQKVSGVVRLKLYKGNVIVIGRESKNSLFNAAYSTFEEDSVYNQKDAAGFIKLNALRFIIAGKANRDK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_CLOB8
Sequence: MKIALIAHDKKKEDIIEFSKKYKDVLAKYELVATGTTGTKISEATGLEVKRYLSGPYGGDQQLGGRIAEGKIDLVIFFTDPLTAQPHEPDVSALLRVCNVHNVAVVTNIKTAELIIKQF
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: GLO2_ECOLI
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Type II glyoxalase that catalyzes the hydrolysis of (R)-S-lactoylglutathione to (R)-lactate and glutathione (PubMed:25670698, PubMed:17196158).  Is more efficient than the isozyme GloC, and plays a major contribution to methylglyoxal (MG) detoxification in E. coli (PubMed:25670698).  The two isoenzymes have additive effects and ensure maximal MG degradation (PubMed:25670698).
What are the official names of this protein?
Hydroxyacylglutathione hydrolase GloB, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: SORC2_HUMAN
Sequence: MAHRGPSRASKGPGPTARAPSPGAPPPPRSPRSRPLLLLLLLLGACGAAGRSPEPGRLGPHAQLTRVPRSPPAGRAEPGGGEDRQARGTEPGAPGPSPGPAPGPGEDGAPAAGYRRWERAAPLAGVASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESSLWRSSDFGTSYTKLTLQPGVTTVIDNFYICPTNKRKVILVSSSLSDRDQSLFLSADEGATFQKQPIPFFVETLIFHPKEEDKVLAYTKESKLYVSSDLGKKWTLLQERVTKDHVFWSVSGVDADPDLVHVEAQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGSLTVQDDYIFFKATSANQTKYYVSYRRNEFVLMKLPKYALPKDLQIISTDESQVFVAVQEWYQMDTYNLYQSDPRGVRYALVLQDVRSSRQAEESVLIDILEVRGVKGVFLANQKIDGKVMTLITYNKGRDWDYLRPPSMDMNGKPTNCKPPDCHLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSVDEGLTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFSRQCGEEDYSSWELSNLQGDRCIMGQQRSFRKRKSTSWCIKGRSFTSALTSRVCECRDSDFLCDYGFERSSSSESSTNKCSANFWFNPLSPPDDCALGQTYTSSLGYRKVVSNVCEGGVDMQQSQVQLQCPLTPPRGLQVSIQGEAVAVRPGEDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHRYESPGIYRVSVRAENTAGHDEAVLFVQVNSPLQALYLEVVPVIGLNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFSDTGDVRVTVQAACGNSVLQDSRVLRVLDQFQVMPLQFSKELDAYNPNTPEWREDVGLVVTRLLSKETSVPQELLVTVVKPGLPTLADLYVLLPPPRPTRKRSLSSDKRLAAIQQVLNAQKISFLLRGGVRVLVALRDTGTGAEQLGGGGGYWAVVVLFVIGLFAAGAFILYKFKRKRPGRTVYAQMHNEKEQEMTSPVSHSEDVQGAVQGNHSGVVLSINSREMHSYLVS
What is the function of this protein?
SorCS2 104 kDa chain and SorCS2 18 kDa chain together promote Schwann cell apoptosis in response to proBDNF.
What are the official names of this protein?
VPS10 domain-containing receptor SorCS2.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family. SORCS subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Early endosome membrane. Recycling endosome membrane. Synapse, synaptosome. Perikaryon. Cell projection, dendrite. Cell projection, dendritic spine. Postsynaptic density membrane.
Protein: LEUC_ACIAD
Sequence: MAGTTQGAKTLYDKLWDDHLVSQRDDGSCLIYIDRHLLHEVTSPQAFEGLQLAGRQPWRLNANIATPDHNVPTSKKEREQGIAGIEDDTSRIQVQTLDDNCKTFNIVEFGINDIRQGIVHVVGPEQGLTLPGMTVVCGDSHTATHGAFGCLAHGIGTSEVEHVLATQCLIQKKSKNMLIRVDGQLGKGVTPKDVVLAIIGKIGTAGGTGYAIEFGGQVFRDMSIEGRMTVCNMAIEAGARVGMVAVDDKTIEYVQSRHYAPKGEQWDQAVAYWNTLHSDDDAVFDEVVVLNGAEIEPQVSWGTSPEMVIPVSQAVPTLEQAKDDVQRNDWTRAYQYMGLTAGQALADIQLDRVFIGSCTNSRIEDIRAAAEVVKGRKVASSIKQAMIVPGSGLVKQQAEQEGLDQVFLEAGFEWREPGCSMCLAMNSDKLQPGEHCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAIAGHFVDVRSF
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CECB_DROSI
Sequence: MNFNKIFVFVALILAISLGNTEAGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATARG
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-B.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS5_PELPD
Sequence: MSRVNPADLNLTDRVVHISRVAKVVKGGRRFSFSALIVVGDGCGYVGYGLGKANEVPEAIRKGVEQAKKNLIKVPVNQNQTIPFEIEGKFGAGRLLMKPASAGTGVIAGGAARAIFEAAGINNILSKCLGSNNPHNVVKAAFAGLQRLKSPEELAARRGITE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RL11_FRATN
Sequence: MAKKKIEAIIKLQVAAGKANPSPPIGPALGQHGVNIMGFCKEFNAKTQGMEPGMPIPVEISVYSDRSFTFEMKTPPASYLIKKAINVKSGSSKPSKEFVGTITRAQLEEIAKVKDPDLTAADLDAAVRIIAGSARSMGVKVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.