PharMolix/UniProtQA huggingface dataset:
Protein: YGD6_SCHPO
Sequence: MALRYVVHDEISGFDQLKPEEYEVPQKLNPGEVLVKLKAASLNYRDLIITKGLYPLPLQLPVVPGSDGAGIIEKVGEDVEGFEKGDSVVCNFFTNYLDGTPTDFATHSALGGTRDGCFQKYAVLPAHALVHAPKNLSFEEIATLPCAAVTAWNGLFGSKEHQVKPGNNVLVLGTGGVSTFALQFALAAGANVTVTSSSDEKLEFAKKLGATHTINYKKTPQWASPALKMTNGVGYHHVIEVGGEKTLPQSIACLAKDGMISMIGFVASEGTTPNLTSIIGQILNRNANIRGIFVGSVSMFRDMVACIEAKDIHPVVDKVFPFDQLKEAYEYQWSQAHIGKVVLKID
What are the official names of this protein?
Zinc-type alcohol dehydrogenase-like protein C1773.06c.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_HAES1
Sequence: MDLLQQLQNQLNQFPSHTKLLLGFSGGLDSTVLLSLLAKLRKKQPHLSLRAIHIHHGLSQNADNWAIHCRQICQQLDISFLCEKVTINPRKGIEADAREARYQAIANHLQDNEILVTAHHQQDQTETFLLALKRGSGLQGLGAMQIQSVVFNLPIFRPLLHCTRQQLEQYAKTEKLSWIEDESNADNRYDRNFLRNDILPKLRQRWQHIDKAIQRSAQHCFEQQQLINELLNDEFNKIYDKFDRTLSIANFATYSILKQKALLRTWLQHLHILMPSTIQLDNIMRNMIQAQEDRNPTCKLGNQVLRRYQKRLYATPILQDLSHIRLDIQANECINLPDNLGEICLLTKNEHLQVTWQDKQILLPLTQEKIEIRFRYSGKVKLPQGFHQEMKKCWQDHNVPIWQRTRIPLIFYGDTFKSAVGFFDNFE
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIB1_YEAST
Sequence: MVIKEDCINNLARWQADEEAHSCFQCKTNFSFLVRRHHCRCCGRIFCSSCTENFVNYNKKRVHALQKKNSDVESPPYRTCNECYDNLLHLNLLVSSTNRDVRLSQTSVPPNALALSAPDSNTDEDAEILEDSVDQSGTACRSEESSQNEEDHFCPICNSDLTQFPDEEETRKHVEDCIQRAENAQQHTNTSDAADDSVKESPAFQNRMLVYKISPNTTDNAIKECPICFENMEPGEKVGRLECLCVFHYKCIKNWFHKRAQMTAAQKGNGHAFVKRNFCPFHDAVF
What is the function of this protein?
Functions as an E3 ubiquitin-protein ligase.  Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate.
What are the official names of this protein?
E3 ubiquitin-protein ligase PIB1, Phosphatidylinositol 3-phosphate-binding protein 1, RING-type E3 ubiquitin transferase PIB1.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: TADA_RICCN
Sequence: MEQALKQAKIAFDKNEVPVGAVVVDRLHQKIIASTHNNTEEKNNALYHAEIIAINEACNLISSKNLNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGVVESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFKRIRTVISSHRMT
What is the function of this protein?
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
What are the official names of this protein?
tRNA-specific adenosine deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: TXN4B_MOUSE
Sequence: MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSADLSKMAAIYLVDVDHTPVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNVPKYDLLYQDI
What is the function of this protein?
Essential role in pre-mRNA splicing.  Required in cell cycle progression for S/G(2) transition (By similarity).
What are the official names of this protein?
Thioredoxin-like protein 4B.
What is the protein family that this protein belongs to?
Belongs to the DIM1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RK33_LIRTU
Sequence: MAKGKDVRGIVILQCTSCVRNDFNKESRGTSRYITQKNRHNTPSRLELRKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DB109_PANTR
Sequence: MRLHLLLLILLLFSILLSPVRGGLGPAEGHCLNLSGVCRRDVCKVVEDQIGACRRRMKCCRAWWILMPIPTPLIMSDYQEPLKRKLK
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 109, Defensin, beta 109.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROA_BURCH
Sequence: MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALGKLGVKLARDGDTCVVTGTRGAFTAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHERPIGDLVDGLRQIGAQIDYELSEGYPPLRIKPATISVDAPIRVRGDVSSQFLTALLMTLPLVKAKDGQAVVEVDGELISKPYVDITIRLMARFGVTVERDGWQRFVVPAGVRYRSPGRIMVEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVTMGDDWIDVRGIGHDHGKLEPIDMDFNLIPDAAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELRKVGAIVEEGPDYLVVTPPEKLTPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVGKTFPDYFDRFAALAKA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDPD5_CHICK
Sequence: MVKHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTKWERLWFLILTSSFFLTLVWFYFWWEVHNDYNEINWFLYNRMGYWSDWSIPILVTTAAGFTYITVLLILALCHIAVGQQMNLHWLHKIGLMTTLITTVVTMSSIAQLWDDEWEMVFISLQATAPFLHIGALAAVTALSWLIAGQFARMEKATSQMLMVTAYLAVVVALYLVPLTISSPCIMEKKALGPKPAIIGHRGAPMLAPENTLMSFQKAVEQKIYGVQADVILSYDGVPFLMHDKTLRRTTNVEEVFPGRAYEHSSMFNWTDLEMLNAGEWFLRNDPFWTAGSLSRSDYLEAANQSVCKLADMLEVIKDNTSLILNFQDLPPDHPYYTSYINITLKTILASGIQQQAVMWLPDTERQLVRQIAPAFQQTSGLKLDAERLREKGIVKLNLRYTKVTNEDVRDYMAANLSVNLYTVNEPWLYSILWCTGVPSVTSDSSHVLRKVPFPIWLMPPDEYRLIWITSDLISFIIIVGVFIFQNYHNDQWRLGSIRTYNPEQIMLSAAVRRSSRDVKIMKEKLIFSEINNGVETTDELSLCSENGYANEMVTPTDHRDTRLRMN
What is the function of this protein?
Glycerophosphodiester phosphodiesterase that promotes cell cycle exit and drives spinal motor neuron differentiation (PubMed:16195461, PubMed:19766572, PubMed:23329048).  Mediates the cleavage of glycosylphosphatidylinositol (GPI) anchor of target proteins: removes the GPI-anchor of RECK, leading to release RECK from the plasma membrane (PubMed:23329048).  May contribute to the osmotic regulation of cellular glycerophosphocholine (By similarity).
What are the official names of this protein?
Glycerophosphodiester phosphodiesterase domain-containing protein 5, Glycerophosphocholine phosphodiesterase GDPD5, Glycerophosphodiester phosphodiesterase 2, Phosphoinositide phospholipase C GDPD5.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Cell projection, growth cone.
Protein: RRAS2_HUMAN
Sequence: MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVIF
What is the function of this protein?
GTP-binding protein with GTPase activity involved in the regulation of MAPK signaling pathway, thereby controlling multiple cellular processes (PubMed:31130282).  Involved in the regulation of MAPK signaling pathway (PubMed:31130282, PubMed:31130285).  Regulation of craniofacial development (PubMed:31130282, PubMed:31130285).
What are the official names of this protein?
Ras-related protein R-Ras2, Ras-like protein TC21, Teratocarcinoma oncogene.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid- anchor.
Protein: GWD2_ARATH
Sequence: MATSKSQQFQLIEGMELQITVTGLPNGSSVRAEFHLKNCTRAWILHWGCIYQGNNHWYIPSEHSSKQGALQTTFVKSGDAYVVILELRDPRVRAIEFVLKDGSHNRWLRQHNGNFRVEIPWNDLHAHHRIPKTLIERRAHKIWDRKGRPQSSAREQQIDYDNAVRELHAELARGISLDELQANSTVPVEKEETSEPHHTMIQSYRRKHDVQKWLQKYTEPINRSGSVKSSALAELSKRSVGQENLVSQKSFHVRNYEITVLQRDVKGDCRLWIATNMAGPTVLHWGVAKSSAGEWLIPPPDVLPEKSKFVHGACQTQFTDMSSREHSYQFIDINLKRGGFVGIQFVIWSGGYWVNNNGANFVVNLKSADSTSGKLDVDEKYVLKWLLDEISEREKEAERSLMHRFNIATELTERCKDEGEGGCIGIMVWMRFMATRHLTWNKNYNVKPREISEALERFTNLMEKIYLQQPNKREIVRLTMALVGRGGQGDVGQRIRDEILVIQRNNHCKSGMMEEWHQKLHNNSSADDVIICEALLNYVRSDFRIDAYWQTLQTNGLTKERLASYDRPIVSEPRFRSDSKEGLIRDLTMYLKTLKAVHSGADLESAIDTFLSPSKGHHVFAVNGLSPKLQDLLNLVKRLVREENTEPLIEKLVDARIQLHPALRAPRTRAKDLLFLDIALESCFKTTIEKRLISLNFNNPPEIIYVICVVLENLCLSIVNNEEIIFCTKDWYRVSEAYRPHDVQWALQTKAVLDRLQLVLADRCQHYFTIIQPTAKYLGQLLRVDKHGIDVFTEEVIRAGPGAVLSTLVNRFDPSLRKIANLGCWQVISSADAYGFVVCVNELIVVQNKFYSKPTVIIASKVTGEEEIPAGVVAVLTPSMIDVLSHVSIRARNSKICFATCFDQNVLSNLKSKEGRAISIHTKSTGLVISDGNNSDVSVRHIFISSVPRGVISKGKKFCGHYVISSKEFTDERVGSKSYNIKFLRERVPSWIKIPTSAALPFGTFENILSDDSNKDVARRISVLKDSLNRGDLTKLKSIQEAILQMSAPMALRNELITKLRSERMPYLGDESGWNRSWVAIKKVWASKWNERAYVSCKKNKLDHDAVCMAVLIQEVICGDYAFVIHTNNPVSGDSSEIYTEIVKGLGETLVGAYPGRAMSFITKKTNLKSPTVISYPSKRIGLYSKPSIIFRSDSNNEDLEGNAGAGLYDSVIMDEAEEVVVDYSREPLIMDKSFRVRLFSAIAEAGNVIESIYGCPQDIEGVVKGGHIYIVQARPQV
What is the function of this protein?
Mediates the incorporation of phosphate into alpha-glucan, mostly at the C-6 position of glucose units.
What are the official names of this protein?
Alpha-glucan water dikinase 2.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: DPOL_ASHV
Sequence: MHPFSQLFRNIQSLGEEEVQELLGPPEDALPLLAGEDLNHRVAGLNLQLPTADLDWVHQTNAITGLYSTQTAKFNPEWKQPDFPKIHLSEDLFLNYNNFCGPLTVNEKRKLKLNFPARFFPKATKYFPLSKGIKNNYPDFSIEHFFAAATYLWTLWESGILYLRKNQTTLTFKGKPYSWGHRQLEQHNGQQHESHLQSRESSSMVASSGHILHKQHASGPSSFPTRDLPNNFFGESQKSARTGGSVREKIQTNRLGFPGKSKITIGQQGSSQVSSPRSKSSNFRNQTQANHSSWNQRHPTWYSTTSNTTQSRQREETYSSDSAFKRHSPSFEHEKSEPSSSGLCGGTESLNNTGTSTFCLWRSFYNTEPCGAYCLHHIVSSLEDWGPCTISGDVTIRSPRTPRRITGGVFLVDKHPHNSSESRLVVDFSQFSRGHTRVHWPKFAVLNLQALANLLSTNLQWLSLDVSAAFYHIPVSPAAVPHLLVGSPGLERFTPSMSHTTIHGNNSKLQTMHNLCSRHLFNSLLLLFKTYGRKLHLLAHPFIMGFRKLPMGVGLSPFLLAQFTSALASMVRRNFPHCVAFAYMDDLVLGARTHEHLTAIYSHICSVFLDLGIHLNVAKTKWWGHHLHFMGYVITGAGILPQDKHVQKVSTYLKSIPLNKPLDYKICERLTGILNYVAPFTKCGYAALLPLYQATSRTAFVFSSLYHSWLLSLYAELWPVARQRGVVCSVSDATPTGWGICTTYQLISPTGAFALPIATADVIAACLARCWTGARLLGTDNSVVLSGKLTSYPWLLACVANWILRGTSFCYVPSAANPADLPSRGLLPALHPVPTLRFRPQLSRISLWAASPPVSPRRPVRVAWASPVQNSEPWFPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: LCN10_HUMAN
Sequence: MRQGLLVLALVLVLVLVLAAGSQVQEWYPRESHALNWNKFSGFWYILATATDAQGFLPARDKRKLGASVVKVNKVGQLRVLLAFRRGQGCGRAQPRHPGTSGHLWASLSVKGVKAFHVLSTDYSYGLVYLRLGRATQNYKNLLLFHRQNVSSFQSLKEFMDACDILGLSKAAVILPKDASRTHTILP
What is the function of this protein?
May play a role in male fertility.  May act as a retinoid carrier protein within the epididymis.
What are the official names of this protein?
Epididymal-specific lipocalin-10.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y6335_DICDI
Sequence: MDILLNLINYSNNLKSQIKNNNNPENGSIVVLLSNISNDFEEIKDLQYKQQQQQQQNPNNIIKTFSNTIFKRIKHFISISINFGIKTIATKLLLIKKRKNITSSTSTSTCTTITIDKIINTILFENLNIIIKLLSLIEMIIIREYNYCKNTITQQQQQPILIWIGNSTNNNNKNKKIKIINLESIEKSINYLKTIKQQNKNTRIIIDNDIPLDHIKQLLSQFNNFPINIICFKNKCKNNEKEKKEEEEDHDHDHDDKKKEKEDKEKEEEEEEEDSNDDFEINDYITFLSIDFNNHFISLSNTEILYDYFINSMNYKPKFITTTTTTTTTTVNGSKNSSNTTTPITTKDDIDLDSDGEKKESDDDDDDDLTDEDTSQHNEIYSTSPKVSHSTFCQSSPTLLDLDLQQQQQQQQQQNDKIGGQQEKQITPNRSYTIRNMKPVSNQRYYSTPNKTVIINQQQQQQQQQQSSTSPSISPSSSNIKSEPNFARIDYKTSMFISNKPVAITTGKVATTQIHLRDALDNPVPTNLTSSNPSGFGPISSSPLHLTLLGPTNEILPFYCFVVGSGIFGISFFPTIHGIYTLSASLDYNNNNNNNNNNNNNSNNNNGIKKDLSIKNSPTIFKSTADGIISPNEIRSLHNSNEKKRKLPLLDFESTSNDSIDLLDFIIDSVDKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKENHNQNQNEIENENKNENENENENDKNGIIFINQNLNKEFNESSPEMSPTLQVEDDSNISAVNNDSSEIEATLAI
What are the official names of this protein?
Putative uncharacterized protein DDB_G0285031.
Protein: NIPLA_DANRE
Sequence: MNGDMPHVPITTLAGIAGLTDLLNQLPLPSPLPGTTTKSLLYNGRVAEDVGHLLGCRDETLVSQLANSLSQVSTEHIELKDSLGSDELEGDVPVLLQLLMSRNPNIFRNKTAPNTPQYPAQAGISQQSMAPPYKITHGSMQGSPASANYQQASMSHSPSGHFVPGQSGPGGRFLPQQGSPVPSPYAPQSPATGYRQYPHPPAYSQHQHLQQGSVASPMIPGAMRNVHENKDQMRMGFTSHLLQSSPPYTPPCDGTKDLHLGSQDKQRGQKSSEGEQDSPDKATVYDIVGSPAKDHTKLILRPSRARPAEVELGGMYPGSDPEGELVEALAAIERMESEAAMETERSAKEVQDKDKPLKKRKQDSHPQEPGAAGTAGSGSGAPGGGGGANAGHRLAPQEASAAGTSASRPGLQVSLEQAGRVEDDCMGMPIPASEAQRWPQEPQEGVTPKAVKHEHDHDPEHPHYDDKQPDTPRQKHRPEGRHGDGGAQRAAVQSGSKQVELPPYMLGENTGVLKNFTIPKIRKGELGGGDIPEGWKQPCVRLERLEADVDVKKSVKPVVVLQKLSIDEVQRLMRERDSRASKSGKNRLSSGRSGKGGIDPSVLKDLPPELLAEIESTMPLCERVKMNKRKRSTVNERPKYAEDSSEDEEFSSRKRQRKDRDRTWEAEERDRRSSGEHRRGNFDARRGSGSRYDDSDQDSPPPSLNEVARRLKMKQKKRKVYEPKLTPEEMMDSSTFKRFTLSIDNILENLEDVDFTAQDDDEIPQELLLGKQQLNELGSESAKIKAMGITSRIPSDKLVKLLNILEKNILDGASLSTLMNLDNEGEDEERLWRDLIMERVTKSADACLTALNIMTSTHMPKAVYIEDVIERVLQYTKFHLQNTLYPQYDPVYRVNPKGGSMLSSRAKRAKCSTAKQKVIIMLYNKVCDVVSNISELLEIQLMTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDDEGEPIYIQMVSALVLQLIQCVVHLPADRDSEDDHKKVDDDVFITNSYETARRTAQNFLSVFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPDWPASELLLSLLGRLLVHQFSNKQTEMALRVASLDYLGTVAARLRKDSVTSRMDQKAIERIIRENTEGDETQRLQKALLDYMDENAETDPALAFARKFYIAQWFRDCTTETEKAMRSQNQKEDDSDGAQHAKELQATGDIMQRAETRKKFLHSVVKSTPNQFTTLRMNSDTVDYDDACLIVRYLASTRPFSQSFDIYLTQILRVLGESAIAVRTKAMKCLSEVVAVDPSILARSDMQRGVHGRLMDNSTSVREAAVELLGRFVLSRPQLTEQYYDMLIERILDTGISVRKRVIKILRDICLEQPNFSKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPNHDKETMNRKILNITDVVSACKDTGYDWFEQLLQNLLKSEEDSSYKPTRKACVQLVDNLVEHILKYEEALAEHKSVNSTRLVACITTLYLFSKIRAQLMVKHAMTMQPYLTTKCSSQSDFMVICNVAKILELVVPLMDHPSESFLTTIEEDLMKLILKYGMTVVQYCVSCLGAIVNKVTHNYKFVWACFNRYYGALTKLKVQHQEGTNSMALAATKAALLRSLFTAGALCRHFDFDLEQFKGTTKVVIKEKVLELLLYFTNHEDEEVKCKAIIGLGFLFIMHPSQMFVPEVKTLYNGLLSDKRSSITLKIQVLKNLQMYLQEEDTRMQEADREWQKLSKQEDLKEMGDISSGMSSSIMQLYLKQVLESFFHAQSSVRHFALNVIALTLSQGLIHPVQCVPYLIAMGTDAEPTMRNKADQQLVEIDKKYTGFIHMKAVAGMKMSYQVQQAVFGSAGSVIRGFRQDESNSAQCSHLYSMVRANRQHRRAFLISLLNLFDDSSKMEVNMLLFIADNLAYFPYQSQEEPLFIMHHIDITLSVSGSNLLQTFKESLVKIPGRKSRKRRRRRRRPQRQQPPPPPPQQQQQQNGSEEERGAQDEERERHSGDEEYDDDDYEEDEDGHRVRKPKPTEDIRQSESDSDSDLDDVDAVMERLPDDSTSLVDFARASQGILLLLVLKQHLKNLYGFSDGKIQKYSPSESAKVYDKAVNRKTLANFNPQQTIDFLRHHDVHGELTYELKRKIVKQFLDFKLLMEHLDPDEEDEDGDTSANVRNKAITALLGGAAASPRNHHTGDSEEDDERSEGEERTPGASRRGRRTGDSADLLSANMNESVSALDIIAIHCPKYRDRPQIARVIQKNSDGYSIHWMAGSYSSTWAEAKKRDGRKLVPWVDSIKETDIIYKKITLTSGNKLNHKVAQTLRSLYAAKDRNSS
What is the function of this protein?
May play a structural role in chromatin.  Involved in sister chromatid cohesion, possibly by facilitating the cohesin complex loading.  Transcription factor, which may promote cortical neuron migration during brain development by regulating the transcription of crucial genes in this process (By similarity).
What are the official names of this protein?
Nipped-B-like protein A.
What is the protein family that this protein belongs to?
Belongs to the SCC2/Nipped-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PME38_ARATH
Sequence: MVFGNEMCDETPHPGECKTLLIKHKPIRSTTQFLQVSVERTLDGAVKAKSDTYFLEPQFGSKQAWEECMDLYEQTIHRLNESVLCPKNVCSRSDVQAWLSTALTNLDTCQEEMSELGVSSHSLESITIDVINTLAINKRMEQNGKEFGISKITMKTLSIGEKVDVVVAQDGSGDYKTIQEAVNGAGERLKGSPRYVIHVKQGVYEEYVNVGIKSNNIMITGDGIGKTIITGDKSKGRGFSTYKSATFVAEGDGFVGRDITIRNTAGPENHQAVALRSNSDMSVFYRCSIEGYQDTLYVHSGRQFFRECDIYGTVDFIFGNAAAVLQNCRIFARNPPNGVNTITAQSRFNPNQTTGIVIHNSVVKGAPGVQLGGVKTYLGRPWRSYARTVVIGTYLDTLIEPNGWIDWDNVTALSTLYYGEYQNSGPGSGTENRVDWAGFHVISDIQEAREFTLPKFIDSASWLPPTKVPFTINL
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Putative pectinesterase/pectinesterase inhibitor 38.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: HMDH_GIBFU
Sequence: MDHEGCQGQHPQQCCQWVSNAWSEFLDLLKNAETLDIVIMLLGYIAMHLTFVSLFLSMRKMGSKFWLGICTLFSSVFAFLFGLVVTTKLGVPISVILLSEGLPFLVVTIGFEKNIVLTRAVMSHAIEHRRIQAQNSKSGKRSPDGSTQNMIQYAVQAAIKEKGFEIIRDYAIEIVILVIGAASGVQGGLQQFCFLAAWTLFFDFILLFTFYTAILSIKLRSTVSSVMSICVWPLRMMASRRVAENVAKGDDELNRVRGDAPLFGRKSSSIPKFKVLMILGFIFVNIVNICSIPFRNPSSMSTIRTWASSLGGVIAPLSVDPFKVASNGLDAILPTAKSNNRPTLVTVLTPIKYELEYPSIHYALGSAASNPAYNDAFHHHFQGYGVGGRMVGGILKSLEDPVLSKWIVIALALSVALNGYLFNVARWGIKDPNVPEHNIDRNELARAREFNDTGSATLPLGEYVPPTPMRTQPSTPAITDDEAEGLHMTKARPANLPNRSNEELEKLLSENALREMTDEEVISLSMRGKIPGYALEKTLGDFTRAVKIRRSIIARNKAAADITHSLDRSKLPYENYNWERFFGACCENVIGYMPLPVGVAGPLVIDGQSYFIPMATTEGVLVASASRGCKAINSGGGAITVLTADGMTRGPCVAFETLERAGAAKLWLDSEAGQDMMKKAFNSTSRFARLQSMKTALAGTNLYIRFKTTTGDAMGMNMISKGVEHALSVMANDGGFDDMQIISVSGNYCTDKKAAALNWIDGRGKGVVAEAIIPGEVVRSVLKSDVDSLVELNVAKNLIGSAMAGSVGGFNAHAANIVAAIFLATGQDPAQVVESANCITIMKNLNGALQISVSMPSLEVGTLGGGTILEPQGAMLDILGVRGSHPTNPGDNARRLARIIGAAVLAGELSLCSALAAGHLVRAHMQHNRSAAPSRSTTPGSSHDARLTGHDQCPRALSVNNVDERRRYSEVKAIDE
What is the function of this protein?
HMG-CoA reductase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (By similarity).  In this module, the cytosolic acetyl-CoA acetyltransferase catalyzes the formation of acetoacetyl-CoA (By similarity).  The hydroxymethylglutaryl-CoA synthase then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA (By similarity).  The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase HMGR (By similarity).
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductasee.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PAN2_SCHPO
Sequence: MDAWKEITKTTENDGVSTCSLSSIAFDPYSELVWTGHKNGQIKSSFGPSLTSYTQFIGHEGPVHQVLPQERGVFSLSSKSLRLSNRKGTIRWRYQDSDCIDYRAMFYQSRNNPEVVIGGYHQKLTVVNAERGISIHKDKNVSDIFIMRRNRLLCCGSTNGEIILRDPNSFQPVNKVVAHTGTISDIDTSGNLLLSCGYSLRHGTYMLDPFVKVWDLRNLSSLVPIPFPAGPTIIRMHPKLSTTAVVCSCSGQFHIVDTGNPLDAKLMQIPLTSYLTGMDIASTGDAMVFTDVEDNIHLWSPLENPSFSDLKLPIQLPNTSTETVQLENNDPLNSIGLPYYKDELLSSWSKYLIFDVGKPILDSNLLIAKQISENSHPVPQEIKSFHRNQIIEVPWLNRKLISEGATPKFHSERQKDIMSGNDIEGSASYFEEIEDTISGPDSIPKFYQRPVIKYSKFGIEDFDFGFYNKTKYAGLETDITNSYCNSVLQLLSYVPSFSKAAISHSLGPCDLMECLLCELGFLFAMLKESTGRNCQATNFLRAFSNSSFAQSLGIVFDDYSDGTFPDSFVIQKFTKFMLTEISRIADYEDKKDGTSFPVSFLLKSFCIPEMQTYRCGICGITSQKIKSSLYIIDLHYPSQQLESILSFEWLFKMSLDRRVDLPPGWCEYCLAHQPFLLRSFIRSLPDCLFINTQVKHHEHWKLWARKNWLPKKLHLRRVNDTMQCVSQKISNLDKDQQSLSVYVLRGIIYEIRQNGEEPHFVSTIRVSDNTSSDNPDDNRWYIFNDFLVKEVTEEEALTVHGPWKIPIIVYYEKLDTKIPQWDEVSDYTLLYQPYSLNKNPPINKIQPLTTDEMLYPKMLVGIDSEFVALQQEETEVRSDGTKSTIKPSKLSLARVSVLRGEGPNKGLPFIDDYVATDDKVTDYLTEYSGIHPGDLDPDRSPYNVVPLKVAYKKLRLLVNAGCIFVGHGLQKDFRIINLLVPPEQVVDTVDLFFLSSRQRKLSLKFLAWYLLDEEIQLTEHDSIEDALTALKLYDCYDKLKSQGKLEETLDNIYEVGRRFKFRPPSVASMSLEDRNSYGDESVISNQTN
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by xrn1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit pan2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_CARHZ
Sequence: MSEAIKDITEIMNILPHRYPFLLVDKILEVVPGEKAVGIKNVTINEPFFQGHFPGRPIMPGVLLLEAMAQVGAVAILTDERYAGKLPMFAGIDGARFRKPVLPGDQVVFEVELLKIKGSLGKARGSGKVNGELVVEAEILFALA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX8R_ANDMA
Sequence: MNYLTMISLALLVMTGVESGVRDAYIADNKNCIFTCYRDSYCKTECIKNGAETGYCIWIGEYGNACWCIKLPNKVPIKVPGKCNGR
What is the function of this protein?
Binds voltage-dependently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Neurotoxin 8-related gene product 1/2/3, Amm VIIIrgp1, Amm VIIIrgp2, Amm VIIIrgp3.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH60_ALKCK
Sequence: MAKDIQFSEEARRSMLKGVDTLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDIAGDGTTTATVLAQAMIREGLKNVTSGANPMGIRKGIEKATAAAVKELKAISKPIEGRESIAQVAAISSADEEVGQIIAEAMERVGNDGVITIEESKGFSTELEVVEGMQFDRGYASPYMVSDSDKMEAVLDNPYVLITDKKITNIQEVLPVLEQVVQQSRPVLIIAEDVEGEALATLVLNKLRGTFNAVAVKAPGFGDRRKAMLEDIAILTGGQVITEDLGLDLKSATIESLGRAAKVVVTKENTTIVEGAGDPEQISGRVNQLKAQVEETTSEFDKEKLQERLAKLAGGVAVLKVGAATETEMKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVIKAVKAVDATGDEATGVNIVLRALEEPVRQIAHNAGLEGSIIVEKLKAEEVGVGYNAATGEYVNMVETGILDPVKVTRSALQNAASVSAMFLTTEAVIADKPEENAGGADMGGMGGMGGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.