PharMolix/UniProtQA huggingface dataset:
Protein: GROB_BOVIN
Sequence: MAPAATAAAPRLLRAAMLLLLLVAAGRRAAGAPVVNELRCQCLQTLQGIHLKNIQSVKVTTPGPHCDQTEVIASLKTGQEVCLNPTAPMVKKIIDKMLNKASAN
What are the official names of this protein?
Growth-regulated protein homolog beta, GRO-beta.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARL8B_HUMAN
Sequence: MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS
What is the function of this protein?
(Microbial infection) During infection, coronaviruses such as SARS-CoV-2 and the chaperone HSPA5/GRP78 are probably co-released through ARL8B-dependent lysosomal exocytic pathway for unconventional egress.
What are the official names of this protein?
ADP-ribosylation factor-like protein 8B, ADP-ribosylation factor-like protein 10C, Novel small G protein indispensable for equal chromosome segregation 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Late endosome membrane. Lysosome membrane. Cytoplasm, cytoskeleton, spindle. Cell projection, axon. Synapse. Cytolytic granule membrane. Note=GTP- bound form resides on lysosomal membranes, whereas GDP-bound form is likely associated with microtubular structures (PubMed:16650381). Localizes with microtubules at the spindle mid-zone during mitosis. In dendritic cells, localizes to MHC II+ compartments (By similarity).
Protein: ISPE_CLAMS
Sequence: MTSAATSSDAVHARAPGKINVSLTVGALQEDGYHDVATAYQAVSLYEDVYATRSDGFSVEFGGSIDTSRLTTGGDNLAIRAARLLARSTGHRGGVHLRIEKDVPIAGGMGGGSADAAATLLACDTLWGTERTRDQLLALGAELGADVPFALAGGTAIGTGRGDRLSPALAKGTFQWVLAIAEFGVSTPDVYGELDKHRERHAQDIFPAQQIPQVDSGVLQALRAGDPHMLAEVLHNDLQAPALHLAPGLGEVLQLGEENGALAGIVSGSGPTVAFLASDLDSALELQIALSAARLQVIRATGPVHGARIITG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ORR24_ORYSI
Sequence: MTVEERQGRVGGHGVSGGGGGRDQFPVGMRVLAVDDDPTCLKILENLLLRCQYHVTTTGQAATALKLLRENKDQFDLVISDVHMPDMDGFKLLELVGLEMDLPVIMLSANGETQTVMKGITHGACDYLLKPVRLEQLRTIWQHVIRRKNCDAKNRGNDDDAGQKAQGMNNEGESIGANRNKRQSRKSRDENGDDGDDSDENSNENGDSSTQKKPRVVWSVELHRKFVAAVNQLGIEKAVPKKILDLMNVENITRENVASHLQKYRLYLKRLSTDASRQANLAAAFGGRNPAYINMNSFGNYNAYGRYRTVPTAGHTQANNILTRMNSPSAFGVHGLLHSQPIQLGHAQNNLSTSLNDLGGLNNGNMIRGAQMSTILTGPSGNSFPNISNGAPLATANRSLQPLESSSQQHLSRVHSSSADPFSTLVGESPQFPDLGRTTNTWQTAVPSNIQDRGHNDNMSQATLHMNGPKIEPVSSFTSSNQIPLLGNEMQGQVASLASNVPIAFNQDTSPFNYGSSTNSRDMLNNSHVFSNSSINTSLPNLSLDNPAVPKQTLDRGNTGIVSPMQDGRIHHQAVSNQLNYNDDLMRTTGLQRGLSGGLDDIVVDMFRPDREDDGVPYIDGDWELV
What is the function of this protein?
Transcriptional activator that binds specific DNA sequence.  Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  May directly activate some type-A response regulators in response to cytokinins.
What are the official names of this protein?
Two-component response regulator ORR24.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TILS_WOLWR
Sequence: MELELLFQNVVNSFAFYNNQVAVAVSGGVDSIVLLHLMTNWAKKNKLSLPTALTVNHGLRPESQKEADFVVSYAKELGAKESFILNWEKQNIKGNIQLQARKARYKLLAEWCKNNNVKYLLVAHHKDDQAETFLLRLERGSGVDGLSSMDYKSFLNGIYIFRPLLNFSRSEIEKYAKLHRLKWIEDRSNYDLKYRRTLYRNLLKASDNQEILTERICLTALHMKRAAKALMHYTRLAFNDCVNVHDLGYIEIKLSEFYQLPEEIALRLLLYSIMAIASKHYKPRYNSLIVIFNKILQKDSNVNCTLSGCKIRKHGENILIIRESSKIQEITLNLPLNEPTQWDNRFSCTILGNQECSVIIAPLKKTQKVPEFLKDYNCCPEVFYSLPVVLKDGKVLAYPDVNYNGKNTNDDKVQCIINSTIKQNLVSLISI
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_STRPM
Sequence: MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVDQDTVLRRSLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTKTADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAENKEGAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RS9_BRUO2
Sequence: MAESINSLEELGTVAKTEAAAPVHVQKLDAQGRAYATGKRKDAVARVWVKPGTGKITVNDKEFEKYFARPVLQMILQQPIVASNRAGQFDIVATVAGGGLSGQAGAVRHGISKALTYYEPGLRTVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CDH_SHIBS
Sequence: MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLANISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQCEILR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: WAKLC_ARATH
Sequence: MKTKTYNFRYIVASVLTLLMNGSSAATPPNSNSSSSCNRTFGGISIPFPFGIGGKDCYLNSWYEVVCNSTTSGSCKTVPFLTRINREVVNISLPKSDFFSPYGVVHIKGPVTSLGCSSNISQGLQKTLPDLNITGRGSPYFLTDENRLVAVGCGTKALMTDIESEILGCESSCKDTKSNEVGNSLCNGYKCCQARLPVERPQAVGVNIESNNDTRGEGCKAAFLTSMKYFPSNITKPEWFQADGYAVVELGWYFDTSDSRFRNPLGCTNLTRSSGSYFLTDICLCRYGYFSRMSYRSCYCGSGYRGNPYIRGGCIDIDECEVPNKCGEDTCVNMAGRYSCVPKITKPAKLAHVLRGVLIGLLGLLFFVIGIFGLYKFIRKRRRIIRSMKFFKRNGGLLLKQQLTTKDGSVEMSKIFSSRELEKATDNFSIDRVLGQGGQGTVYKRMLVDGSIVAVKRSKVVDEDKMEEFINEIVLLSQINHRNIVKLLGCCLETEVPILVYEYIPNGDLFKRLHDEYDDYMMTWEVRLRIAVEIAGALSYMHSAASFPIFHRDIKTTNILLDEKYRAKISDFGTSRSVATDQTHLTTLVAGTFGYMDPEYFLSSQYTHKSDVYSFGVVLVELITGEKPMSRVRSEEGIGLATYFLEAMKENRAVDIIDIRIKDESKQVMAVAKLARRCLNRKGNKRPNMREVSIKLERIRSSPKDLDVHTENEEEEEEDQLMEINRIYDS
What is the function of this protein?
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.
What are the official names of this protein?
Wall-associated receptor kinase-like 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SL9A2_MOUSE
Sequence: MGPRGTAHSVRAPLSWLLLLLLSLQVAVPAGALAETLLDAPRARGASSNPPSPASVVAPGTTPFEESRLPVFTLDYPHVQIPFEITLWILLASLAKIGFHLYHKLPTIVPESCLLIMVGLLLGGIIFGVDEKSPPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFENFGTIFWYAVVGTLWNSIGIGVSLFGICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSFCQMKTIQTVDVFAGIANFFVVGIGGVLIGILLGFIAAFTTRFTHNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAFCLIWRALGVFVLTQVINWFRTIPLTFKDQFIIAYGGLRGAICFALVFLLPATVFPRKKLFITAAIVVIFFTVFILGITIRPLVEFLDVKRSNKKQQAVSEEIHCRFFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKLLIRENQPKSSIVSLYKKLEIKHAIEMAETGMISTVPSFASLNDCREEKIRKLTPGEMDEIREILSRNLYQIRQRTLSYNRHNLTADTSERQAKEILIRRRHSLRESLRKDNSSNRERRASTSTSRYLSLPKNTKLPEKLQKKKKVSNADGNSSDSDPDVGTTVLNLQPRTRRFLPDQFSKKASQAYKMEWKNEVDVGSVRVPPSVSPAPRSKDGGTQTPGLLRQPLLSKDQRFGRGREDSLTEDVPPKPPPRLVRRASEPGNRKGRLGNEKP
What is the function of this protein?
Plasma membrane Na(+)/H(+) antiporter (PubMed:14962844, PubMed:16690903).  Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+) (PubMed:14962844).  Major apical Na(+)/H(+) exchanger in the base of the colonic crypt (PubMed:14962844, PubMed:16690903).  Controls in the colonic crypt intracellular pH (pHi) to direct colonic epithelial cell differentiation into the absorptive enterocyte lineage at the expense of the secretory lineage (PubMed:34985202, PubMed:14962844).
What are the official names of this protein?
Sodium/hydrogen exchanger 2, Na(+)/H(+) exchanger 2, NHE-2, Sodium/hydrogen exchanger, Solute carrier family 9 member 2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Protein: RLF13_ARATH
Sequence: MKAWVICLLVICAAVIAEPVESRNYIEYGAINKCAGPNPPPGCNPPGAEQKNPNPVNEYSRGCSKIHRCRRD
What is the function of this protein?
Cell signaling peptide that may regulate plant stress, growth, and development.  Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
What are the official names of this protein?
Protein RALF-like 13.
What is the protein family that this protein belongs to?
Belongs to the plant rapid alkalinization factor (RALF) family.
What are the subcellular locations of this protein?
Secreted.
Protein: EF1A_THECE
Sequence: MAKEKPHINIVFIGHVDHGKSTTIGRLLFDTANIPENIIKKFEEMGEKGKSFKFAWVMDRLKEERERGITIDVAHTKFETPHRYITIIDAPGHRDFVKNMITGASQADAAVLVVAVTDGVMPQTKEHAFLARTLGINNILVAVNKMDMVNYDEKKFKAVAEQVKKLLMMLGYKNFPIIPISAWEGDNVVKKSDKMPWYNGPTLIEALDQMPEPPKPTDKPLRIPIQDVYSIKGVGTVPVGRVETGVLRVGDVVIFEPASTIFHKPIQGEVKSIEMHHEPMQEALPGDNIGFNVRGVGKNDIKRGDVAGHTNNPPTVVRPKDTFKAQIIVLNHPTAITVGYTPVLHAHTLQVAVRFEQLLAKLDPRTGNIVEENPQFIKTGDSAIVVLRPTKPMVIEPVKEIPQMGRFAIRDMGQTVAAGMVISIQKAE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURE_PYRHO
Sequence: MVISMKSEKPLVGIIMGSDSDLPVMKEAARILEEFGVPYEITIISAHRTPERAYEYAKKAEERGIEVIIAGAGGAAHLPGIIASLTVLPVIGVPIKSKALNGLDSLLSIVQMPSGIPVATVAIDNAKNAALLALRILGIKYPEIKEKLRRYMKDMKRKVEEKAKRLEEMGWERYLSE
What is the function of this protein?
Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide mutase, N5-CAIR mutase, 5-(carboxyamino)imidazole ribonucleotide mutase.
What is the protein family that this protein belongs to?
Belongs to the AIR carboxylase family. Class I subfamily.
Protein: YCF12_RIPO1
Sequence: MELLAALNLEPIFQLTFVGLIMVAGPVVIFLLAFRGGDL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PABT_STRGR
Sequence: MRVTVDSEQCVGAGQCVLNAPEVFDQDDDGVVVLLRADPTSGTTRRSARRATCARRPRSSSRRTEPAGCADRHRCPVRPGPRTRGPADPPPANTDRRQNHRRDSPVTTADDTAARWLRRYHPAEADAVRLVCFPHAGGSASFYHPVSARFAPGAEVVSLQYPGRQDRRKEPCVPDLGTLADLITEQLLPLDERPTVFFGHSMGAALAFETAWRLEQKGAGPRTVIASGRRGPSTTRAERVHTRDDDGIVAEMKRLNGTAAGVLGDEEILRMALPALRGDYRAIETYTCPPDRRLACGLTVLTGEDDPLTTVEEAERWRDHTTGPFRLRVFTGGHFFLTQHLDAVNTEIAQALHPDRAAPAA
What is the function of this protein?
Probable thioesterase involved in the biosynthesis of candicidin.  Could release the macrolide ring from the polyketide synthase.
What are the official names of this protein?
Probable cadicidin biosynthesis thioesterase, ORF-1, Protein X.
What is the protein family that this protein belongs to?
Belongs to the thioesterase family.
Protein: VDAC3_PIG
Sequence: MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLRTKSCSGVEFSTSGHAYTDTGKASGNLETKYKICDHGLTFTQKWNTDNTLGTEISLENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKRECFSIGSNVDIDFAGPTIYGWAVLALEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYKLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).  Involved in male fertility and sperm mitochondrial sheath formation (By similarity).
What are the official names of this protein?
Voltage-dependent anion-selective channel protein 3, VDAC-3, Outer mitochondrial membrane protein porin 3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Membrane. Note=May localize to non-mitochondrial membranes.
Protein: KDSB_ARATH
Sequence: MSVCSSSSSSQKTWIVNGILAGTAIAAAIGARAYLGRSKKFRSRVVGIIPARYASSRFEGKPLVQILGKPMIQRTWERSKLATTLDHIVVATDDERIAECCRGFGADVIMTSESCRNGTERCNEALEKLEKKYDVVVNIQGDEPLIEPEIIDGVVKALQVTPDAVFSTAVTSLKPEDGLDPNRVKCVVDNRGYAIYFSRGLIPYNKSGKVNPDFPYMLHLGIQSFDSKFLKVYSELQPTPLQQEEDLEQLKVLENGYKMKVIKVDHEAHGVDTPDDVEKIESLMRERNMS
What is the function of this protein?
Catalyzes the production of the sugar nucleotide CMP-3-deoxy-D-manno-octulosonate (CMP-KDO).  CTP is the preferred nucleotide donor, but it can partially be replaced with UTP.  Activates KDO during the biosynthesis of rhamnogalacturonan II (RG-II), a structurally complex pectic polysaccharide of the primary cell wall.  RG-II is essential for the cell wall integrity of rapidly growing tissues and pollen tube growth and elongation.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, mitochondrial, CMP-2-keto-3-deoxyoctulosonic acid synthase, AtCKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.
Protein: RBFA_RICRO
Sequence: MKKLTKTHSHRQQKLASIINEALIEILRRGKMLDSRLFDCPLTITKVIVTTDLKIANCYFLPFNTKLTIDEIMDALNNSKNAIRNFITNKIHMKFSPDIRFHYDHGFDNAIKVAHLLKDL
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_SALG2
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFRPYNGFTLDFTIDFNHPAIDSSSQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDDAELPLAFKAPSTVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: HIS6_METNO
Sequence: MLKTRVIPCLDVKDGRVVKGVQFLDLRDAGDPVEAAKAYDRAGADELCFLDITASHEARGILLDVVQRTAEACFMPLTVGGGVRTVEDIRALLLAGADKVSINTAAVNNPDFVAEAAEKFGAQCIVVAIDAKRVSGPGEPPRWEIFTHGGRRATGIDAVAFARTVTARGAGELLVTSMDRDGMRSGYDLGLTRAIADAVSVPVIASGGVGGLDDLVAGVAEGHASAVLAASIFHFGEATVAQAKAHMAAAGLAMRLDP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOXZ_PARDE
Sequence: MRFCRGTVLGRSAAGMAVLLALGACYEEDDQTLPSAAPGESVAAESTHWLEIDDSRSPETFLSAESGLPAQTLAPLLGALSAHYRESPRMIANRVLQLWQEYPDTPLERIMADLVPARDAPEESLGPVAQQYRVLRAGGAGHADAVAAAMGQRE
What are the official names of this protein?
Protein MoxZ.
Protein: SYGA_PSEPF
Sequence: MSQPTPAVRTFQDLILALQQYWAEQGCVVLQPYDMEVGAGTFHTATFLRAIGPETWNAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVLKPNPDNFQELYLGSLKHVGLDPLVHDIRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGIECYPVTGEITYGLERLAMYLQGVDSVYDLVWADGPFGKVTYGDVFHQNEVEQSTYNFEHANVDKLFELFDFYESEAKRLIELDQPLPLPSYEMVLKASHTFNLLDARRAISVTARQQYILRVRTLARSVAQAYLLARAKLGFPMATPDLRDEVLAKLEAAQ
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_LEPIC
Sequence: MSERSYYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGNKESEEKFKEATEAYEILRDPKKRQAYDQFGKAGVSGGAGGFGQGAYTDFSDIFGDFGDIFGDFFGGGRSSGFGGGRRSGPQRGSDLRYNLEVSLEDAALGREYKIEIPRLESCVDCNGSGASKGSSPATCPDCGGSGQIRRTQGFFSVATTCPTCRGKGTIISNPCRSCGGQGLQEKRRTINIKIPPGVETGSRLKVSGEGEAGPNGGPHGDLYVVTHIKKHELFERQGNDLILVRKISLAQAILGAEIEVPTIDGKKAKMKIPEGTESGQVFRLKGHGMPYLGAYGKGDQHVIVKIEIPKKITRRQRELIEEFARESGENIPGSKGKIFTK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX36A_PHOKE
Sequence: KAKCADIDQPCKTSCDCCETKGACTCYKSGCVCRMGSFXATCKK
What is the function of this protein?
Neurotoxin.  Causes spastic paralysis and death in mice within 10 minutes at dose levels of 3 ug per mouse.
What are the official names of this protein?
U4-ctenitoxin-Pk1a, U4-CNTX-Pk1a, Neurotoxin PKTx28C4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UBP46_HUMAN
Sequence: MTVRNIASICNMGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE
What is the function of this protein?
Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action.  May act by mediating the deubiquitination of GAD1/GAD67 (By similarity).  Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:19075014, PubMed:26388029).  Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP12/USP46 subfamily.
Protein: ATP6_ECOL5
Sequence: MASENMTPQDYIGHHLNNLQLDLRTFSLVDPHNPPATFWTINIDSMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS1_METCA
Sequence: MLTIAVSKGRIYQEALPLLAEAGIVPSVDPDKSRKLILPTERDDVQLVIIRAADVPTYVEYGAADLGIAGKDVLVEYEGEGLYEPLDLGIARCRLMTAGPPGRPVASRRLRVATKYVNTAKRFFARRGVQAEVIKLYGSMELAPLVGLADCIVDLVDTGNTLRANGLAPQELIMDISSRLVVNKAAMKMKYGPITELAGHLARIVSARAARER
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYQ_ECO55
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.