PharMolix/UniProtQA huggingface dataset:
Protein: SET2_EMENI
Sequence: MSTHDNADRQSEFVADAVTAMKLEQSENNTDAPILNGGGAAMKPDSKAASPEPLIKDERASSTFMKSRSSSRTPSSRTPLKKEHSDSEDIQEKRGDDASGTEKVGGGISVKMEPGQPPKLARSSSQKVVPRPPQLFLDLPDSTEEAQKTFEVIETCQYANKYMGYTEHAMECDCAEEWVLVVVLAPSPSFRVPSQNPASSTNRACGEDSDCINRATKIECMGDCGCGPDCQNQRFQRREYANVAVIKTEKKGYGLRAEEDLRPHQFIFEYVGEVINEGPFHRRMRQYDAEGIKHFYFMSLSKGEFVDATKKGNLGRFCNHSCNPNCYVDKWVVGEKLRMGIFAERHIQAGEELVFNYNVDRYGADPQPCYCGEPNCTGFIGGKTQTERATKLSNATIEALGIEDADGWDTAVAKRPRKKKMGEEDEEYVDSVQPKSLDESGVTKVMAALMQCKEKWIAVKLLGRIQRCDDERVRNRVVKMHGYQILNSQLAMWKDDFNVVLQILDILDKFPRLTRNKIIDSKIESTIQPLTSCGDERVEQKATVLLQLWSTLEIGYRIPRMKRDPNAATPTVSQFHRRDDISDERQQRPRSRSRSRSIEAPRGPAAQKRGGQGPRNQHHQGPRTFRRRFDPLPQGWFAAESNGRTYYYSARGDTTWTRPTKPAPQPPPPPKESRDKALQSIIDGIMNAKEQTPKEKSGTPTTPQPSKPTPEGKDRQEKWRSYSEEKQKKLYENTLYPHIKYVVDKFKHKLPKDDLKRYAKDVAKKLVNSDFKNNRVTDPTKIDDKQQKKVKKFCKEFFDKAVAKHQAHEKRKAEKLAKEGSSDNKLATPVGGQSEGDGTPDVKMSDDEGSTGREGTGSLKRKRDELSVGNTNTPDDTPTSSTKRQRSSTPPPPPPPAMNTNDNNNDNDDMSVRSDEPDADADADEVVLVGNPTPPPPPPPPPQEDMRIPDADAETNGHNFEGYGEMNRSHQAQIGIEGNV
What is the function of this protein?
Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3.  Involved in transcription elongation as well as in transcription repression.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-36 specific, SET domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CYSZ_VIBA3
Sequence: MTIESVPRSGFGYFIFGIKIALSPSIRKFVLLPLIANVLLVGGALFYIFSNLNTWIEGWIGALPSFLSWLSYILWPLLVLTVLATFSYFFSTLANFIAAPFNGLLAEKVEELLSGKKVNDDGLLDVLKDTPRILAREWRKLVYILPKAIGLFLLLLIPALGQTVAPFLWFIFTAWMLAIQYADYPFDNHKIKFDDMRNNLKQKQGKSYSFGALVSVFTTIPVLNLIVMPVAVCGATAMWVAEFKDQALRSRL
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RMNB_STRAQ
Sequence: MTARPNPVTATVRSDIPMSDTVVSTTYSEQAAHLVARIDQDGLGSVRPSLYETARVISAAPWLPGEPRRLAYLLDEQAPDGSWGEGPERYRLLPTLSGVEAALAVLRRGATPTETARRLAGAVDRGLAALRALPRSGPWPDTAAAEILVPGLVAKIHEQIARIAEDGTPALDGWRPGPGPALPGGYDEALPAYVAKRYASVGSLPVKFHHTFEGIAGYLPPALIPDVPDLLGSSPAATAARAATASSAPSAGTVAALESVAERYAGSFPEAAPILVFERLWVAAALAHTHLPAAALPTVRRWAADIYDPRGVRGAPGLMKDADDTAMAVLVSSLVGLEHTLEPLDQFHNGSHYDCYIGEDTGSITANAHALQALGGYQRRNPETQHIYGPRTDKLRDWLIDQQRPEGPWPDKWHASPYYATARSVAALTRFGGGHAVTAVETAVTWALDTQRDDGSWGVWGGTAEETAYAVQILLSTSTHRPQHTRALHRAETYLGDSAGSGRHPALWHDKTLYAPDAMIEAEILAARQTLRTRHDLNRRVTTPIHAEK
What is the function of this protein?
Involved in the biosynthesis of the labdane-type bicyclic diterpene labda-8(17),12(E),14-triene.  Catalyzes the conversion of geranylgeranyl diphosphate (GGDP) into (+)-copalyl diphosphate.
What are the official names of this protein?
Copalyl diphosphate synthase, Type-B diterpene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: Y1365_METJA
Sequence: MVIILRHVRVFNGVNECDIYLIGTAHVSKDSIEEVEKIISSVSPEGIAVELDDRRFFSLITNEEKKVDLKKVLKEGNFLKFFIYLILANSQKKIGESFGIKPGSEMKKAIEIASKYGLPIYLIDRDIDITLSRLMDRMTFKEKMKIFWELLNSDEEDLELDDDLLNDMVKNPEKFIKLLKEISPTIYEVLVDERDRFMAKRLFELSKNKNSLVAVVGAGHVEGIVRYLKKLENGNDIDLMELIKVKKRKKSLKKLLTYGISLTIISIFLYMICYALNNPELLKMITFQWILFTGGLSALGVLLARGKLITALVAFLSAPITTLVPLPLAAVGTIAGLVELKYREITDKDLVGIINAESIKELLNNNLFRVLLVATLSNLGASIGVFYCLGKFIGFLG
What are the official names of this protein?
Uncharacterized protein MJ1365.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BECN2_HUMAN
Sequence: MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQDGASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKAAGDIFDIVSGQAVVDHPLCEECTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLANTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQFKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKWSLIWVASRYQK
What is the function of this protein?
Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover.  Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1.
What are the official names of this protein?
Beclin-2, Beclin-1 autophagy-related pseudogene 1, Beclin-1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the beclin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPU1_CRIGR
Sequence: MAGEADGPFKRVLVPVLLPEKCYDQLFVHWDFLHVPCLKILLSKGLGLGIVAGSLLVKLPQIFKILGAKSAEGLSLQSVMLELVALTGTVIYSITNNFPFSSWGEALFLTLQTITICLLVLHYRGDTVKGVALLACYATLLLALLSPLTPLAVVTMLQASNVPAVVVGKLLQAATNYHNGHTGQLSAITVFMLFGGSLARIFTSVQETGDPLMAGVFVVSSLCNGLIAAQVLFYWNAKPPHKHKKEQ
What is the function of this protein?
Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.
What are the official names of this protein?
Mannose-P-dolichol utilization defect 1 protein, Suppressor of Lec15 and Lec35 glycosylation mutation, SL15.
What is the protein family that this protein belongs to?
Belongs to the MPDU1 (TC 2.A.43.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IF5A_KORCO
Sequence: MSVTRGSAGDLRKGSYVILDDEPCEVLEVSKSKPGKHGSAKVRVEARGIFDGARRSKIFPADALVEIPIVDKKTAQVINVYGNVVQLMDLETYETFELPLPEDPELASRLKSGIEVEYWESMGKRKIVRTRGGV
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_GEOSM
Sequence: MSRRDDRSDTLICSFCGKSQEEVKKLIAGPTVYICDECIELCNDIIAEESKLEDATATDVRKLPKPQEIKEVLDEYVIGQSRAKKVLAVAVYNHYKRVEAAVKPGDVEMQKSNILLLGPTGSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENIILTLLQASDYDVEKAQKGIIYIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTTNILFICGGAFPGLDSIIQQRIGVKTLGFGADVKKKVEKKAGELLAGVTPEDLLKFGFIPEFVGRLPMLASLSELDEEAMVQILKEPKNALIKQYQKLFDMEHVKLKFTDGSLVAIAREALKRKTGARGLRSILENAMLDIMYEIPSQSMVKEVVINEEVIYSKEKPIIVYENVAESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SYY_MIMIV
Sequence: MENTDHTNNEHRLTQLLSIAEECETLDRLKQLVDSGRIFTAYNGFEPSGRIHIAQALITVMNTNNIIECGGQMIIYIADWFAKMNLKMNGDINKIRELGRYFIEVFKACGINLDGTRFIWASEFIASNPSYIERMLDIAEFSTISRVKRCCQIMGRNESDCLKASQIFYPCMQAADVFELVPEGIDICQLGIDQRKVNMLAIEYANDRGLKIPISLSHHMLMSLSGPKKKMSKSDPQGAIFMDDTEQEVSEKISRAYCTDETFDNPIFEYIKYLLLRWFGTLNLCGKIYTDIESIQEDFSSMNKRELKTDVANYINTIIDLVREHFKKPELSELLSNVKSYQQPSK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: MP_MSVS
Sequence: MDPQNALYYQPRVPTAAPTSGGVPWSRVGEVAILSFVALICFYLLYLWVLRDLILVLKARQGRSTEELIFGGQAVDRSNPIPNLPAPPSQGNPGPFVPGTG
What is the function of this protein?
Involved in the viral transport within, and between cells.
What are the official names of this protein?
Movement protein, MP.
What is the protein family that this protein belongs to?
Belongs to the mastrevirus movement protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: YEGS_ALCBS
Sequence: MSKKALLILHGKQADNQSVRNAVIDWRNQGHELAVRVTWEGGDAERYVREALDNGFKTIIAGGGDGSVRDITQALMENGNSELELAIIPLGTANDFATAAEVSEEPADALSLLNRPAQPCDVIRVNNHYFLNMATGGFGTEVTTQTSEELKKMLGGAAYLLTGLTRFSEIESAKGHFKGEDFEWEGDFLALGLGNGRQAGGGQRLCPDALVNDGLFDVAILPADMDLLAGVKELFDSEARQDPDQEGLFVRTRLSEMKIETPTPMNLNLDGEPIQNTTFQIQAIRNALRLYLPEGCPLLG
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS-like.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_DANRE
Sequence: MVKVGINGFGRIGRLVTRAAFLTKKVEIVAINDPFIDLDYMVYMFQYDSTHGKYKGEVKAEGGKLVIDGHAITVYSERDPANIKWGDAGATYVVESTGVFTTIEKASAHIKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLTVVSNASCTTNCLAPLAKVINDNFVIVEGLMSTVHAITATQKTVDGPSGKLWRDGRGASQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTVRLEKPAKYDEIKKVVKAAADGPMKGILGYTEHQVVSTDFNGDCRSSIFDAGAGIALNDHFVKLVTWYDNEFGYSNRVCDLMAHMASKE
What is the function of this protein?
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively.  Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity).  Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis.  Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Nucleus.
Protein: MUTS_PARL1
Sequence: MSEPATSFTPEIPSALPSIPADATPMMAQYLEIKARWPEALLFYRMGDFYELFFEDAVAASAALDIALTKRGKHLGEDIPMCGVPVHSHDAYLQRLIRKGFKVAVCEQVEDPAEAKKRGAKSVVARAVARLVTPGTLTEDTLLDARAHNYLAALSRTGAEAGFGLAWVDVSTGDFAVTSLAPVALGAELARLSPGELLLPETLDEDEDLAALLAQSGAALTRLPAIRFESGQAERRLKSHLGVSALDGFGAFARAELGAMGALLDYVELTQVGRMPALMPPRRVAATDTMAIDAATRANLELVRTLQGETAGSLLATMDRTVTGAGARELASRLAAPLTDPAAVNRRLDAVEWFHDARDMRARLRAGLKSAPDIARALSRLSLGRGGPRDLAAIANGLAAAHGLCAALDGASPSLLPLPEEIARECEAMRGTAASLQSRLAAMLAEELPLLARDGGFIARGASPELDETRALRDDARKLIAGLQAKYAGESGIAALKIRHNNVLGYYIEVPPRHGEKLLAPPFSDSYIHRQTMANAMRFTTAELAGLASRIAEAAGRALEIELALFDELAAATLLEAPSLSRAAEALARLDATAALAELAAERRYVRPRLDASFAFDIRGGRHPVVEAALARTGQAFVPNDTSLSAESGGGKHIWLLTGPNMAGKSTFLRQNALIAIMAQMGSFVPADEAHIGVVDRLFSRVGAADDLARGRSTFMVEMVETAAILNQAGERSLVILDEIGRGTATFDGLSIAWATVEHLHGVNKSRALFATHYHELTALSEKLAHLANATMRVKEWQGDVVFLHEVAPGAADRSYGIQVAKLAGLPAPVIARAQSVLAALEEGGNHEARTKLIDDLPLFSATAKPAPAVKVSAAEEELKNLNPDELSPKQALELLYKLKALAAKDGE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: CRTP3_DICDI
Sequence: MGSDERKPLLSINDGDDDFNHQDVSTKTPPIKKESLSNKFKSFLKKSMTKETLPILIYVLLYIISGVINVVLLKKLMIKFVNYGFFLSQITNYGYLPIFLVAMWYKMYCTSDVPKETRNFPQYKFVIMGLLDAINGFFVVIGGVSTSGPLQQLLNQAIIPFTMIASFIFLRERYSLFQLGGAAVILGGVIVSLIPSLVGGSSGGNILFYNFFYLISVIPGALSNVYKDIAFQSIDMDVWYLQFWDCLYQSLFGSILFPVNNWLPPPATIKFTEIIPSMRDGALCLGGKNTILPIFNGTTSTLAFGSCGINDNFVCDDCHNTWIIVLIYMTVNIAYNIFILLVLKHAGATVYSIANTVILPLTNIFFSIHFIMGAATTPFSALSVAGLLLILFGLGGYRIGSMIKKPPPDSKKDSEQQGGEGGAGDGDSSDNKNNLGDSAEIPQQIQPKTQLHLRNQFFGRLGIDIPESRYRATNIINN
What is the function of this protein?
May regulate endogenous transporter.
What are the official names of this protein?
Crt homolog 3, Chloroquine resistance transporter paralog 3, DdCRTp3.
What is the protein family that this protein belongs to?
Belongs to the CRT-like transporter family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: ISPE_CHLTE
Sequence: MKHFSVKACAKINLGLLITSRRADGYHTLETIFAPIDWFDTLEFTESDAISMECSNLDLLVDDSNLCIRAAKALQEHTGVKRGATIKLLKRVPFGAGLGGGSSDAAATLNALCKLWQIDVPSAELHKLAVKLGADVPYFLEMKGLAYAAGIGEELEDLNLALPWHVVTVFPEVQVPTAWAYKNFHRQFERPVPDLKTLVRRLCHERDISVFGVFENDFASVVFEHYPVVREVRDALAASGAQFVSLSGSGSAVYALYEGRADAVKAAEAMSARFRINMTPAGFRME
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: AROC_BRUSU
Sequence: MSHNSFGHLFRVTTWGESHGLALGCVVDGCPPGITFTEAEIQSFLDKRKPGQSKYTTQRREPDQVRVLSGVLLGEDGVTMTTTGTPISMMIENTDQRSKDYGEIARQYRPGHADYAYDVKYGIRDYRGGGRSSARETAARVAAGAIARKVVPGLEVRGALVSIGAHDIDRSRWNWAEVDNNPFFTPDAGSVEVFADYLDGIRKNGSSVGAIIEIVAEGVPAGIGAPIYGKLDQDIASYLMSINAVKGVEIGNGFEAARLTGEENADEMRMGNDGKPIFLSNHAGGVLGGIATGAPVVARFAVKPTSSILTPRRSIDKDGNEVDVMTRGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGRV
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HIS4_XANC8
Sequence: MSFTVYPALDIRDGRVVRLLQGDYARETRYGDDVLPRAQAFADAGAQWMHLVDLDAAKAGGYTLAALLGQISRQTGLQVQTGGGVRSREDVARILDAGAARVVVGSLAVRDSATVIGWLQEFGTDRLTIALDTRQDAAGVWQLPVHGWTETAEATLDQLATQYAQAGLQHLLCTDIARDGMLSGPNMGLYAHLRALAPQLQVQVSGGARNLADVAAAKAAGCAGIVLGKALLEGHLDLKDALAC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_HAHCH
Sequence: MSVIKMTDLDLRGKRVLIREDLNVPVKNGKVTSDARIQAALPTIKLAMEQGAKVMVMSHLGRPEEGQFSEENSMQPVGAHLSSLLGHDVPVVRDYLDGDFEVEEGGLVLFENVRFNVGEGKDNEELSKKYAALCDIFVMDAFGTAHRAQASTHGVAKFAPVACAGPLLAAELEALGQALDKPQRPMVAIVAGSKVSTKLDVLNSLSEVCDQLIVGGGIANTFLAAADHKVGKSLCEMDLLDTARSIAAKVQIPLPTDVVTAKAFSESAEASVKPIAEVTDDDMILDIGPQSAAALAELLKSAKTILWNGPVGVFEFDQFGDGTKTLAQAIAESDAFSIAGGGDTLAAIDKYGVSEKISYISTGGGAFLEFVEGKTLPAVAMLQKRAAE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1944_ARCFU
Sequence: MKLTKIRTEGDFNWGPFLTDSDGYFTIPIPDSQAGKKFRIRIEPWDINYAARIARDLDRCNEYVWFLSDEITVPDHGRLDLGELRIGKDANYDFTAYWQEKRHTCLFGLCACGGSVHVIQGGSVYLNIADALLAARAYADLHRSDDDGIGRVDVQYPDSDWSNYDQTWDEITLTTNHGFLDGVAIHEYGHFLEDHISEEDIYVGNTSHTFCDDKDDTEFAWSEGFAEYYGTFIVAINDHLSHPDISFGTIENPGCSKFDDDIEATVAAVLWDMVDNSSFPDYNASESFDTVGGLDDVIFKMFDSELDHWHDAPDLCEMHGNLDHRLDSTTLNKVERIFEHYNACR
What are the official names of this protein?
Uncharacterized protein AF_1944.
Protein: COBT_PSESM
Sequence: MSNSWWLKPAQAIDVPMREAALARQQQLTKPAGSLAQLERLAVQLSGLQGRERPAADKLWIAIFAGDHGVVAEGVSAYPQEVTGQMLHNFVNGGAAISVLARQLSAQLDVVDLGTVSPMDLPGVRHLRIGAGTANFVDGPAMTVEQGLAALQAGRDSVLRAKAVGTELFIGGEMGIGNTAAASAVACSVLECAAPLLVGPGTGLNAEGIVHKTRVIERALALHAEHAGDPLQSLFCLGGFEIAALTGAYLACAQEGIVAMVDGFICSVAALVAVRLNPSCRDWLLFGHRGAEPGHRHLLETLQAEPLLDLGLRLGEGSGAALAVPLVRLACELHNGMATFAEAAVADRPA
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: RL20_TREPA
Sequence: MSRSLSSNGRVRRRKRILKLAKGFRGRCGTNYKAAKDAVSKALAHSYVARRDRKGSMRRLWISRINASVRTQGLSYSRFMNGLLQAGIALNRKVLSNMAIEDPGAFQTVIDASKKALGGGAC
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TREA_SALTY
Sequence: MIPPEIRRSVLLQKAIKLALAGTLLTFASFSATAADPSSDTETPQPPDILLGPLFNDVQNAKLFPDQKTFADAIPNSDPLMILADYRMQRNQSGFDLRHFVDVNFTLPKAGEKYVPPAGQSLREHIDGLWPVLTRSTKNVEKWDSLLPLPESYVVPGGRFREIYYWDSYFTMLGLAESGHWDKVADMVANFGYEIDAWGHIPNGNRTYYLSRSQPPFFAFMVELLAQHEGDDALKEYLPQLQKEYAYWMEGVETLQPGQQNQRVVKLEDGSVLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLSTIRTTTIAPVDLNALLYQLEKTLARASAAAGDRAKASHYDALANARQKAIEMHLWNNKEGWYADYDLKNNKIRDQLTAAALFPLYVNAAAKDRAAKVAAAAQAHLLQPGGLATTSVKSGQQWDAPNGWAPLQWVAAEGLQNYGQDDVAMEVTWRFLTNVQHTYDREKKLVEKNDVSSTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPQEKPCDSVPSTRPASLSATPTKTPSAATQ
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RT109_YEAST
Sequence: MSLNDFLSSVLPVSEQFEYLSLQSIPLETHAVVTPNKDDKRVPKSTIKTQHFFSLFHQGKVFFSLEVYVYVTLWDEADAERLIFVSKADTNGYCNTRVSVRDITKIILEFILSIDPNYYLQKVKPAIRSYKKISPELISAASTPARTLRILARRLKQSGSTVLKEIESPRFQQDLYLSFTCPREILTKICLFTRPASQYLFPDSSKNSKKHILNGEELMKWWGFILDRLLIECFQNDTQAKLRIPGEDPARVRSYLRGMKYPLWQVGDIFTSKENSLAVYNIPLFPDDPKARFIHQLAEEDRLLKVSLSSFWIELQERQEFKLSVTSSVMGISGYSLATPSLFPSSADVIVPKSRKQFRAIKKYITGEEYDTEEGAIEAFTNIRDFLLLRMATNLQSLTGKREHRERNQPVPASNINTLAITMLKPRKKAKALPKT
What is the function of this protein?
Histone chaperone-dependent acetylase that modifies 'Lys-9', 'Lys-14', 'Lys-23', 'Lys-27', and 'Lys-56' on histone H3 (H3K9Ac, H3K14Ac and H3K23Ac, H3K27Ac, and H3K56Ac) to promote nucleosome assembly, genomic stability, DNA repair and transcriptional regulation during mitotic S-phase (PubMed:31194870, PubMed:17046836, PubMed:17369253, PubMed:17320445, PubMed:17272723, PubMed:18723682, PubMed:20560668, PubMed:21256037, PubMed:29300933, PubMed:19172748, PubMed:19683497).  Its residue selectivity is influenced by the acetylation status of histone H3, and also the presence of histone chaperone ASF1 that shifts selectivity to 'Lys-56' when H3K14Ac is already present (PubMed:31194870).  H3K56 acetylation weakens the interaction between the histone core and the surrounding DNA in the nucleosomal particle and drives chromatin disassembly (PubMed:18577595).  Autoacetylates (PubMed:18568037, PubMed:18707894, PubMed:18719104).  Independently of acetyltransferase activity, stimulates histone deposition by VPS75 (PubMed:19172748).  Involved in regulation of Ty1 transposition (PubMed:11779788).
What are the official names of this protein?
Histone acetyltransferase RTT109, Regulator of Ty1 transposition protein 109.
What is the protein family that this protein belongs to?
Belongs to the RTT109 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXB_BORBR
Sequence: MSLRIGMVAGEPSGDLLAGRIIAGLQARAPGVHCAGIGGPQMAARGFEAWHPMHALTVFGYIDAFKRIPSLLSTYGDVKRRLLAEPPSVFVGIDAPDFNLRLEHQLRQAGTPTVHFVGPSIWAWRYERINKIRAAVSHMLVLFPFEEALYRKEGIPVTYVGHPLAGVIPMQPDRAAARARLGIDADARVLAILPGSRSSEIRLLAPRFLQAAAELVRRDPRLQCVVPMVNPQRRAEFEAIAAQHPVPGLRCVTAAEGQGETPVAWSVMEASNAVLVASGTATLETALYKRPMVISYVLSPWMRRIMAWKSGQQRPYLPWVGLPNVLLRDFAVPELLQDEATPAALAEATWQALTDEAGAARIEARFTALHQDLLRDTPALAAQAILEVADGAA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: ZN778_HUMAN
Sequence: MAAPDLAHGGHVSRDSVCLHEEQTQAAGMVAGWLINCYQDAVTFDDVAVDFTQEEWTLLDPSQRDLYRDVMLENYENLASVEWRLKTKGPALRQDRSWFRASNETQTARSHNGGQLCDRTQCGEAFSEHSGLSTHVRTQNTGDSCVSNHYERDFFIPCQKTLFKIGEQFSVLGQCGKAFSSTPNVVSQQACTRDRSLDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCGKALTHSMGCATPVEMHAVRNPHVCRECGKAFRYTAYLTGRVQVHPGEKPCELEECGKASPVSSSLTQHVRIHAAEKPCECKECGKAFTGLSGLSKHVQTDPGQKPYECKDCGKACGGFYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHVRIHTGIKPYTCSYCGKAFTVRCGLTRHVRTHTGEKPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYECKDCGKSFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSGLTKHMRTHTGEKPYECKDCGKAYNRVYLLNEHVKTHTEEKPFICTVCRKSFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTHTGEKPYECKVCGKAFTTSSHLIVHIRTHTGEKPYICKECGKAFASSSHLIEHRRTHTGEKPYICNECGKAFRASSHLHKHGRIHTGQKPYKCKECGKAYNRFYLLKEHLKTYTEEQVFVCKDCGKSFKNSSCLNHHTQIHTDEKPF
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 778.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS21_DROER
Sequence: MENDAGENVDLYVPRKCSASNRIIHAKDHASVQLSIVDVDPETGRQTDGSKTYAICGEIRRMGESDDCIVRLAKKDGIITKNF
What is the function of this protein?
May be an associated component of the ribosome rather than a core structural subunit.  May act as a translation initiation factor.  Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva (By similarity).
What are the official names of this protein?
40S ribosomal protein S21, Overgrown hematopoietic organs at 23B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
Protein: NDK_COXBN
Sequence: MAIERTLSIIKPDAVAKNVIGQIYSRFEKAGLKIIAAKMCHLSKPQAEKFYAVHKDRPFYPDLVKFMTQGPVMIQVLEGENAIVKNREIMGATNPKEALPGTIRADFADSIDANAVHGSDGPETAKEEIAFFFKPDEIF
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.