PharMolix/UniProtQA huggingface dataset:
Protein: SRPP_HEVBR
Sequence: MAEEVEEERLKYLDFVRAAGVYAVDSFSTLYLYAKDISGPLKPGVDTIENVVKTVVTPVYYIPLEAVKFVDKTVDVSVTSLDGVVPPVIKQVSAQTYSVAQDAPRIVLDVASSVFNTGVQEGAKALYANLEPKAEQYAVITWRALNKLPLVPQVANVVVPTAVYFSEKYNDVVRGTTEQGYRVSSYLPLLPTEKITKVFGDEAS
What is the function of this protein?
Involved in the biosynthesis of rubber, an isoprenoid polymer (cis-1,4-polyisoprene).
What are the official names of this protein?
Small rubber particle protein, HbSRPP, 22 kDa rubber particle protein, 22 kDa RPP, 27 kDa natural rubber allergen, Latex allergen Hev b 3.
What is the protein family that this protein belongs to?
Belongs to the REF/SRPP family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Found in latex, the cytoplasm of laticifer cells. Tightly bound to small rubber particles, where it displays a covering effect on the lipid headgroups of the membrane without disturbing its integrity.
Protein: PSAJ_ARATH
Sequence: MRDLKTYLSVAPVLSTLWFGSLAGLLIEINRLFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL27_LIMF3
Sequence: MIMDLQFFSHHKGGGSTANGRNSAGRRLGTKAADGSVVTAGSILYRQRGTHINPGENVGRGNDDTLFALVDGVVKFERLGRDKRKVSVYPVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CH60_FRATT
Sequence: MAAKQVLFSDEARAKMLDGVNTLANAVKVTLGPKGRNVVLDKSFGTPTITKDGVSVAKEIELEDKFENMGAQIVKEVASKTADVAGDGTTTATVLAQALLTEGLKAVAAGMNPMDLKRGIDKATARLVEELKALSKPCSDPKSIEQVGTISANSDATVGKLIADAMAKVGKEGVITVEEGKGFEDELDVVEGMQFDRGYLSPYFATNQENMTTDLENPYILIVDKKISNIRDLLPILEGVSKSGRALLIIAEDVESEALATLVVNNMRGVVKVCAVKAPGFGDRRKAMLEDIATLTGATFVSEDLSMKLEETNMEHLGTASRVQVTKDNTTIIDGAGEKEAIAKRINVIKANIAEANSDYDREKLQERLAKLSGGVAVIKVGAVTEAEMKEKKDRVDDALHATRAAVEEGIVAGGGVALIRAQKALDGLTGENDDQNYGIALLRKAIEAPLRQIVSNAGGESSVVVNQVKANQGNYGYNAANDTYGDMVEMGILDPTKVTRSALQHAASIAGLMITTEAMIGEIKEAAPAMPMGGGMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Released into the host cell cytosol during infection.
Protein: MDM12_ASPFN
Sequence: MSIEVDWRAATSGPDGEALAERIRSFIHDKFQQVALPRFIRSVQVHSFDFGTIPPDLEVKDICEPFADFYEEDEDDETSDVSEELVSGHGTQWHRDLNEPPFHEEMAMNRPLRDPFDEAFHSSTLRSPMEHLNPHFLPRAGTPGIPGGTSTLGYHLMSLGGLSGTQTPLAAVAGGTPFANGWTDPGMGASSRGHPSISGPTAVHPSRMEADIDTSNPTSRPSTSSTLPSHPSASNQPSGDATTGKEHGSLAEDEHLDDPMTSGHPLRLPPRMRERRPEDFQVLCHAKYAGDVRLSLTAEILLDYPMPSFVGLPLKLNVTGITFDGVAVIAYIRKRVHFCFLSAEDADALIGSDQQEARGQDDRPWSSADPTASPKRQGGLLREIRVESEIGRKEDGKQVLKNVGKVERFVLAQVRRIFEEEMVFPSFWTFLI
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: COAW_STAAS
Sequence: MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLEK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type II pantothenate kinase, PanK-II, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type II pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSIA_PECAS
Sequence: MSSPVPGLMLPEKRVVEVRNLSVYFEQQGQRTDAVRNLTFSVDRGETLAIVGESGSGKSVTSLALMRLVEHAGGVIHQGDMLFRRRDGQVLDLRGARQRVMRTLRGADLAMIFQEPMTSLNPVFPVGEQIAESIRLHQRMDRRAARAETLRMLDLVRIPEARNVLDRYPHQLSGGMRQRVMIAMALSCKPSLLIADEPTTALDVTIQAQILQLIRVLQREMDMAVIFITHDMGVVAEVAERVLVMHRGESVEAASVGQIFAAPQHPYTQGLLAAVPALGSMRGQPFPAKFPLLDQNTARIVDNVPQDTVPAHAEPILQVSNLVTRFPIRSGLLNRVTRQVHAVEKVSFDLWPGETLSLVGESGCGKSTTGRALLQLVESQKGDITFDGQRIHQLKGAALQHLRRDIQLIFQDPYASLDPRLTVGFSIMEPLLVHNVCRRQEAEKRVAWLLSRVGLEPEHARRYPHEFSGGQRQRVCIARALALNPKVVIADEAVSALDVSIQAQIINLMLELQREFGIAFLFISHDMAVVERISHRVAVMYMGQIVEIGPRQDVFERPQHPYTRKLMSAVPVADPSRRQREQVLLVDEIPSPIRAIGDEPTTAPLVQVGKRHFVAHHPIAGAY
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Glutathione import ATP-binding protein GsiA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Glutathione importer (TC 3.A.1.5.11) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HEM3_DESVM
Sequence: MKKLVIATRGSKLALWQAEHVKSCIEGQHPGVSVELLVLKTRGDIILDVPLAKVGGKGLFVKEIEEALLDGRADLAVHSMKDVPMELPEGLVLGIIPEREEPSDTFLSVHHDSLAALPHGATVGTSSLRRQSQLLALRPDLNVVSLRGNVDTRLRKLSEGQFDAIIMATAGMKRLGLSAPRSEVLGPPAFLPAVGQGALGIEFRADRADLHELLAFMEHTPTRIRVEAERGFLAGLQGGCQVPIAGHAVMTGDGTFALEGLVADLTGARVIRRTMNGVSAPDGAQARQIGLDLAAQLVADGAGEILAEVYGSGEAVN
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: CLPS_SYNP6
Sequence: MAVETIQKPETTTKRKIAPRYRVLLHNDDFNPMEYVVMVLMQTVPSLTQPQAVDIMMEAHTNGTGLVITCDIEPAEFYCEQLKSHGLEQQH
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: YL455_YEAST
Sequence: MTKDIRTGDLVLCKVGSFPPWPAVVFPQRLLRNDVYRKRKSNCVAVCFFNDPTYYWEQPSRLKELDQDSIHNFILEHSKNANQRELVNAYKEAKNFDDFNVFLQEKFEEENRLSDLKAFEKSEGSKIVAGEDPFVGRTKVVNKRKKNSISIKEDPEDNQKSNEEESKPNIKPSKKKRPTANSGGKSNSGNKKKVKLDYSRRVEISQLFRRRIQRNLIQRETPPTEHEIKETHELLNRIYENSDTKRPFFDLKALRESKLHKLLKAIVNDPDLGEFHPLCKEILLSWADLITELKKEKLQALPTP
What are the official names of this protein?
PWWP domain-containing protein YLR455W.
Protein: KITH_GEOKA
Sequence: MYVMTQSGWLELICGCMFSGKSEELIRRVRRAQFAKQEVKVFKPTIDNRYSEDAVVSHNGNSVIAIPVATPAEMFRYISAATDVVAIDEIQFFSDDIIDVVQTLADCGYRVIAAGLDQDFRGEPFGPVPALMAIAESVTKLQAVCTVCGSPASRTQRLINGAPASYDDPVILVGASEAYEPRCRHHHEVPGKPKKRYNHPLAGHTGE
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TF2B_METM7
Sequence: MKVESVTKEETKKPERKIKLAIAKPEDYSNKNVILEKEEELICPVCGSKNIIKDYERAEIVCEMCGCVLQQNLFDVGPEWRAFDHEQRVKRSRVGAPMTYTIHDKGLSTVIDWRNKDSYGKDISADKRAQLYRLRKWQRRIRVSDASERNLAFALSELDRIASKLGLPRNVRENAAVLYRGAVEKGLIRGRSIEGVAAAALYAACRRCKVPRTLDEIAEVSRVDRKEIGRTYRFISRELNIRLAPTNPVDYVPRFASELKLPGEVESKAISILQKAGEKGLTSGRGPTGVAAAAIYIASVLQGTRRTQREVADVAGVTEVTIRNRYKELTEHLDIDVTL
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: CAPP_YERPP
Sequence: MNEQYSAMRSNVSMLGTLLGDTIKEALGEHILDRVETIRKLSKSSRAGNEASRQELLTTLQNLSNDELLPVARAFSQFLNLTNTAEQYHSISPHGEAASNPEALAQLFTRLKDKKLSDQDMRSAVDDLSIELVLTAHPTEITRRTLIHKLVEVNTCLSQLDHNDLADYERNKIMRRLRQLVAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWEGVPAFLREFNEQLENSLDYRLPVEAVPIRFTSWMGGDRDGNPNVTAEITRHVLLLSRWKATDLFLRDIQVLVSELSMSECTPELRELAGGEEVLEPYRQLMKNVRTQLTNTQAYLEARLKGERVLPPHDLLVSNDQLWEPLYACYQSLKACGMEIIANGQLLDTLRRVRCFGVPLVRIDVRQESTRHTDAIAELTRYLGLGDYESWSESDKQAFLVRELNSKRPLVPLKWEPSAETQEVLETCRVIAEAPQGSIAAYVISMAKVPSDVLAVHLLLKEAGCPFTLPVAPLFETLDDLNNADDVMTQLLGIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYRAQDALIKTCEKAGITLTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKFGLPEVTISSLALYAGAILEANLLPPPEPKKEWIEVMDLLSDASCDMYRSYVRENPEFVRYFRAATPELELGKLPLGSRPAKRRPDGGVESLRAIPWIFAWTQNRLMLPAWLGAGAGLQRAIDAGKQDVLATMCRDWPFFSTRIGMLEMVFAKADLWLAEYYDQRLVDKSLWPLGQQLRDQLAADIKVVLAIANDDHLMADLPWIAESIALRNVYTDPLNVLQAELLHRSRQQEHPDACVEQALMVTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: ELFD_ECOLI
Sequence: MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEGEEQISLGVRNTSPDVPYLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGAPLAKDRETLFFTSVRAVPSTTKRKEGNTLKIATQSVIKLFWRPKGLAYPLGEAPAKLRCTSSADMVTVSNPTPYFITLTDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRTINDYGAETPQLNCKS
What is the function of this protein?
Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces.  Could be required for the biogenesis of the ElfA fimbriae.
What are the official names of this protein?
Probable fimbrial chaperone protein ElfD.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LPTD_LEGPL
Sequence: MAIGITACVLSLINYQGLAYSAALINEPIQACVIAREVDLTDDIRTKFAQCLGWQADQSSPVCLGFYKPITVTPLASPDEVRILADTASFYRTQRSTLSGHVEMQQGQRVVNAQTAYVYRDPKTNEVTKIEFLNHVRYLEPDRMMIARKAVVYPQDKSGEVEDVLYRFNTNRSNALLPAWGRASLIKRFANQDYFLKEATYTTCAPQDKAWAIEAESISINNEKGKGIARNAKLRIHEWPVLYTPYLSFPTNRDRKSGFLMPIVGYSNVGGADLGIPYYWNMAPNYDMTLVPHIYTKRGLMLGGQFRYLTSKSTGTFNGNFLPKDKAFGRFLQDNEVEFPQIRGLSTNRWEVNFVDSTQFLSDLQLNVNFQQVSDDYYLQDFSTNLASVTQRQLLRQADLTYTTENWTFRGMGQSYQTLHPINEIPVSPVYERLPQLMARGYYDDLPFNAQLNILGQYDQFHWPNDSWNIALNNMPQGPRFHLNPILSVPMMKPWGYVTPSVQFVENYYDISRNYTWGTSRANYNLTIPRYSLDGGLYFERDLHLKGTYYIQTLEPRLFYLRVPYYNQTLIPVYDSGFMIFNVDQLFRTNRFSGFDRIGDANQLSYALTTRWLEDESGAEKANFSIGQIKYFSERRVQLCQSPTGFCTDNPDTFGNLSSTFGTSPVASRAVYKFNPAWGITGDYIWDPATRATNNADLNLHYQPARNAIINGGYSYLVNGDVTQVRNNDTENNALHQAILSAAWPLSEKWSGIGAYSYNISKNYSMMSFLGVQYDSCCWAMRILGGRTFRSLNEEFEPRYNNNIYLQILLKGLGSVASSDPSGILNTYIPGYYDPFRRR
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PAX_I05A1
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERSESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKEDRFIEIGVTRREVHTYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVNPREAKRQLKKNLKSLEPCADLPTKVSHRTSPALKTLEPMWMDSNRTAALRASFLKCQKR
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: NUOD_NEIG2
Sequence: MANKLRNYTINFGPQHPAAHGVLRMILELDGEQIVRADPHIGLLHRGTEKLAETKTYLQALPYMDRLDYVSMMVNEQAYCLAVEKLAGIDVPIRAQYIRVMFAEVTRILNHLMGIGSHAFDIGAMTAILYAFRDREELMDLYEAVSGARMHAAYFRPGGVYRDLPGFMPKYESSKFRNAKVLKQLNESREGTMLDFIDAFCERFPKNIDTLETLLTDNRIWKQRTVGIGVVSPERAMQKGFTGVMLRGSGVEWDVRKTQPYEVYDKMDFDIPVGVNGDCYDRYLCRMEEMRQSVRIIKQCADWLRVNPGPVITANHKFAPPKRTEMKTGMEDLIHHFKLFTEGMHVPEGETYTAVEHPKGEFGVYIISDGANKPYRLKIRAPGFAHLQGMDEMAKGHMLADVVAIIGTQDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CRS2_MAIZE
Sequence: MSLLAAAIPSTSSHFSAPFLPSFRMPRKSLTAPLHRIRRPRPFTVVSSVPDPAAGPVEYTPWLIAGLGNPGNKYYGTRHNVGFEMVDRIAAEEGITMNTIQSKSLLGIGSIGEVPVLVVKPQSYMNYSGEAIGPLAAYYQVPLRHILLIYDDTSLPNGVLRLQKKGGHGRHNGLQNVIEHLDGRREFPRLSIGIGSPPGKMDPRAFLLQKFSSEERVQIDTALEQGVDAVRTLVLKGFSGSTERFNLVQKYKFHRV
What is the function of this protein?
Required for the splicing of group IIB introns in chloroplasts.  Forms complexes with either CAF1 or CAF2 which, in turn, interact with RNA and confer intron specificity of the splicing particles.  Has no peptidyl-tRNA hydrolase activity.
What are the official names of this protein?
Chloroplastic group IIB intron splicing facilitator CRS2, chloroplastic, Chloroplastic RNA splicing factor 2, Protein CHLOROPLAST RNA SPLICING 2.
What is the protein family that this protein belongs to?
Belongs to the PTH family. CRS2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RLF7_ARATH
Sequence: MSARKKNRIHVFFVSIMIIISLVSGFGEGIKQINYKDLIKDTIPGCTSKNPKECVKVPANTYHRGCEISTRCHREQHSSSG
What is the function of this protein?
Cell signaling peptide that may regulate plant stress, growth, and development.  Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
What are the official names of this protein?
Protein RALF-like 7.
What is the protein family that this protein belongs to?
Belongs to the plant rapid alkalinization factor (RALF) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL19_RAT
Sequence: MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_DICT6
Sequence: MIALLSINFVAFFVFLLILKYWINFQRNKGIGKYIRKEGPSSHFQKSGTPVMGGIVFILAVFPFLFFKETFFISLSTILFGLLGLVDDLKLMENKDYGIRPLRKIFLSFIITLILYVFSPHDYKIYWGSHLIIDSSILYIFLFFIILIAVPNAINLTDGLDGLAGGTSLVTLIFLLVYSFHFKKIALEISLMITALLAFLWFNSHPAEIFMGDVGAFALGGFIASLSVVNKVELLLIFLSGIFLIESLSVFIQVFFYKWKKKRIFLMSPIHHHFELKGWKETKIVWRFYIIHLLIIIGGLVLWYWS
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEDD2_MOUSE
Sequence: MALSGSTPAPSWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAPGGLARARSGLELLLELERRGQCDESNLRLLSQLLRVLARHDLLPHLARKRRRPVSPERYSYGNPSSSSKRTEDSCRRRRQASSSSDSPQSQWDTGSPPTKRQRRSRGRPSSGARQRRRAGLAASQQHQQHQELGRPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGRRGTEAS
What is the function of this protein?
May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus.  May regulate degradation of intermediate filaments during apoptosis.  May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.
What are the official names of this protein?
DNA-binding death effector domain-containing protein 2, DED-containing protein FLAME-3, FADD-like anti-apoptotic molecule 3.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Nuclear, accumulated in subnuclear structures resembling nucleoli.
Protein: NU2M_ANOGA
Sequence: MKKISNNIFLIMLIFGTLVTISSNSWLGAWMGLEINLLSFIPLMNDNKKNLLTSESSLKYFLTQAFASSILLFAIIMLMFLYNNNLSLYNSFNEILILSTLLLKSGAAPFHFWFPEVMEGLSWVNGLILMTWQKIAPLMLISYNFIYNFFMISIILSMLIGSLGGLNQTSIRKLMAFSSINHLGWMLLAMMNNEMLWMTYFLMYSLLSFSIVLMFNNFKLFYFNQIFNLSMMNPIIKLLIFLNLLSLGGLPPFLGFLPKWLVIQNLTAMNQLFILTISVCLTLITLYFYLRLSYSIFMLNYQKNSWMLKNNFNNKMSSISLIFNFISIGGLVMISMIYIIM
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIGA_ECOL6
Sequence: MIAIADILQAGEKLTAVAPFLAGIQNEEQYTQALELVDHLLLNDPENPLLDLVCAKITAWEESAPEFAEFNAMAQAMPGGIAVIRTLMDQYGLTLSDLPEIGSKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Functions as an mRNA interferase antitoxin.
What are the official names of this protein?
Antitoxin HigA.
What is the protein family that this protein belongs to?
Belongs to the HigA antitoxin family.
Protein: PAN2_ASPFU
Sequence: MEADWDELSRIPVPPPSPHGLPTVATTIAFDDVSELLWAGNEFGRITSFYGPELQRYTSVRAHPVSDGPVRQILFHERGVISLSPKSVHMITRRGLTQWHISHEEMTDLYCMSFTAQLNKIIVAGCQRAMFTIDIDKGIIVDKLHTDHNYTMMKKSRYLCAATDTGSVNALSLTDFRVVKSWKSHGTAINDMDARNDLLVTCGFSVRHLGSPIVDPLANVYDLKTLSPLPPIPFHAGAAYVRMHPKLSTTSFVASQTGQLQVVDLMNPNAINLRQANVSFMLGIDISPSGEALAINDAECSIHLWGSPSKIHFNEMSKEVEFADVVPRPPPLDWSPDTPLNMIGMPYYRERLLSAWPSHLVFEVGSPPAPIDQSLIPYLRPAEMGHYAPNPKKTRRYQVENTRALTTAEPALIAPKFLSEKAREQSKFKSEASVSDTAEALAGAKLNGEAEDDPLLKYSNVEIKYSRFGVDDFDFSFSGLETHIANSFTNALLQLLKFIPLVRNLALHHAASTCIYETCLLCEMGYLFDMLEKANGQNCQATNLLKTFSSYREASNLGLLEENLTTKSLSSAIQSVNRFFLNQIAHDFRMIVPSSDDLDHRLSTIASESIRCMFCQNEIVRPGNSLANELIYPTIDIKQARRNPAFRFSSILRASIERETQNRGWCNYCRRYQQVTIRKSIHRMPLVLILNAALSNAICRRLWSIPGWLPEEVGIAVDNGQVMCFEGDELKTQLQNKLPNLVVYELVGLVSEIDIPEHQKPHLVSFINVSISSREPEAKNRWHLFNDFLVTEVDKDEALRFNQPWKSPCILAYQVKDARHAVDDSWKNVLDTTLLFRDWSLNGGRAVETRQTLTEEEKPTPGTPVALDTEFVDLEKAEIDVKADGSQEIVRPSKSGLARVSVLRGSGVHEGVPFIDDYITIKEPIVDYVTQYSGIKPGDLDPRTSQHNLVPLKVAYKKLWLLLNLGCVFVGHGLASDFRKINIQVPKSQTVDTQYLYFHPGKNRRLSLRYLAWAVFKEYIQEEPADNNQGHDSIEDARMALRLWKKFQEYEDAGIVNQILEEIFREGSKLGFRPPPRNGVATVLSRPGTAVTMQNSSGRNTPSTPDVGGAATATATTSAPATPRQAFRRSIALTPSNGTFSGPGAGDFFGGSPLK
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by xrn1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit pan2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB2_PYRAR
Sequence: MGEEVQIGATAVGIKAKDGVVLAAEKRVSYGFYTLSSAGRKVFVIDDKLAIASAGIIADMQSLARIVKINAKAYELETRKKPTVRSMAKLLSVIMFSRRYMPFFAEVLVGGVDEEGSHLIVMDPLGSLIEDNYAALGTGAKLAISVLDTGYREDITLQDAKKLAVKALKAAIERDPVSGGGIDLVLIDQTGAKEEEVKVQLLI
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLD_SALTI
Sequence: MAKNYYDITLALSGICQSARLVQQLAHQGHCDADALHVSLNSVIDMNPSSTLGVFGGSEANLRLGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSAKGALNTLGDRINGLQRQLDHFDLQSDTLMSAMAGIYVDVISPLGPRIQVTGSPAVLQSPQVQAKVRASLLAGIRAAVLWHQVGGGRLQLMFSRHRLTTQAKQILAYLTPEL
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.