PharMolix/UniProtQA huggingface dataset:
Protein: MNHC2_STAAS
Sequence: MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGTYGSSRSEPLITGGNQLFVDPLLQAIVLTAIVIGFGMTAFLLVLVYRTYKVTKEDEIEGLRGEDDAK
What are the official names of this protein?
Putative antiporter subunit mnhC2, Mrp complex subunit C2, Putative NADH-ubiquinone oxidoreductase subunit mnhC2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMN_MARMS
Sequence: MTDIKKVNLLGLSPEKLIEFFESIGEKKFRATQVIKWIHQKGAESFEEMTDVSKALRAKLEQICEIRGPEVVSQNISTDGTRKWIIRTEGGKNDCVETVLIPDGDRATLCVSSQVGCSLDCSFCSTGKQGFNRNLTPAEIIGQVWIAIKSFGPMDPNGPRRVTNVVMMGMGEPLMNFEPVVDAMILMMHDHAYGLSKRRVTLSTSGVVPKIYELVKRTDVSLAISLHAPNDALRNELVPINKKYPIAELLEACQFYLENLPDKRHITIEYTLMSGVNDNEEQAHELAELLKVLECKINLIPFNPFPHSGYEKPSNNRTRRFQKILADAGYTVTVRTTRGDDIDAACGQLVGDFHDKTRRSQKYIELREVKS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_STRP6
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ACKA_BORBU
Sequence: MKILIINTGSSSLKFAIYQYENSKKIISGIVEKIKSQKSIIKIVNTDGSTTERFEKGIENHQKAIEKMFKILTNSDLKILKTLSEIKIIGHRVVHGGSSLKNSVILNNSILNKLKQISELAPLHNPNAITAIEAVLKILPHAKQVLCFDTSWHQTIKEHAFLYAIPYSWYKNHNIRKYGFHGLSYSYITKRSSEILNKKIDSLNLIILHLGNGASINAVKNGKSYDTSMGITPLEGLAMGTRSGDIDPSIINLMSTILNKTTKQIEEILNKESGILGISEKSNDMRDIWNKIEEGEYQSKLAVEIMTYRIKKYIGSYIAALDFNVDAIVFTGGIGVTDYGIRALALKGFEKIGIELDLEKNEMAQSKYLESEISTINSKLKILAIPTNEESTILEDIYNLIPKNL
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLE_LACPL
Sequence: MSSKAEKDIKWGIAPIGWRNDDIPSIGKDNNLQQLLSDIVVAGFQGTEVGGFFPGPEKLNYELKLRNLEIAGQWFSSYIIRDGIEKASEAFEKHCQYLKAINAPVAVVSEQTYTIQRSDTANIFKDKPYFTDKEWDEVCKGLNHYGEIAAKYGLKVAYHHHMGTGIQTKEETDRLMANTDPKLVGLLYDTGHIAVSDGDYMALLNAHIDRVVHVHFKDVRRSKEEECRAKGLTFQGSFLNGMFTVPGDGDLDFKPVYDKLIANNYKGWIVVEAEQDPSKANPLEMAQIAHRYIKQHLIEN
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: THIRX_METJA
Sequence: MVRVMVVIRIFGTGCPKCNQTYENVKKAVEELGIDAEIVKVTDVNEIAEWVFVTPGVAFDDVIVFEGKIPSVEEIKEELKSYLEGK
What is the function of this protein?
Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase (By similarity).  Has low thioredoxin activity in vitro (By similarity).
What are the official names of this protein?
Thioredoxin.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
Protein: MURG_VEREI
Sequence: MTGSKTALIMAGGTGGHIFPGLAVAEALRARGWRVHWLGAPASMEARIAAQHGFALESVTFSGVRGKGLATLALLPLRLLRAFWQARAVLRRVQPDVLVGLGGYISFPGALMGLLRRKPLVLHEQNAVAGLANRLLAGRADRVFAAFPGAFGSAAPKARWVGNPLRAAFTQQAGPAERFAARTGPLQLLVMGGSLGARALNELVPQALALLPAAQRPQVLHQSGATQIEALRAHYAAAGVQAELRPFIDDVACALAAADVIVCRAGASTVSEIAAVGAAALFVPLPSAVDDHQTRNARWLVDAGGGWLLPQHELSPRGLAQMLSNLERPALLDKALKAHAMQKTSATQELVGACEELAA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UP02_FRUSA
Sequence: VTLDVED
What are the official names of this protein?
Unknown protein 2 from 2D-PAGE.
Protein: CHMP5_XENTR
Sequence: MNRLFGKSKPKVPPSTLTDCISNVDSRSESIDKKISRLDAELVKYKDQMKKMREGPSKNMVKQKALRVLKQKRMYEQQRDNLNQQSFNMEQTNYAIQSLKDTKTTVDAMKVGAKEMKKAYKQVKIDQIEDLQDQLEDMMENANEIQEALSRSYGTPEIDEDDLEAELDALGDELLLDDDTSYLDEAASAPAIPEGVPNDSKNKDGVLVDEFGLPQIPAT
What is the function of this protein?
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 5, Chromatin-modifying protein 5.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein.
Protein: RSMG_BACCR
Sequence: MNIEQFQSMLEEKGITLSSRQLEQFKIYFETLVEWNEKMNLTAITEKEEVYLKHFFDSITAAFYYDFSKPFSICDVGAGAGFPSIPLKICFPHLKVTIVDSLQKRINFLNHLAQKLELSDVAFCHDRAETFGKKEGVRESYDIVMARAVARLSVLSELCLPLVKVGGTFIAMKGAAANEEIENGKYALEVLGGELKEMSTFQLPFEESERNILLIEKKRKTPKKYPRKPGTPNKLPIEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHE_HAEIN
Sequence: MKKYNKLRIEWDCRRGMLELDKIIMPFYLTHFHELTDDKKDIFIRLLASTDLQLFSWFFNLAKSQDVELQMMVEYIQKVQKIIIN
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YADH_ECO57
Sequence: MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGNLIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPTHVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLNGVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGFLGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS
What are the official names of this protein?
Inner membrane transport permease YadH.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYDND_BRUA1
Sequence: MHRYRSHTCAALRKTDVGSNVRLSGWVHRVRDHGGILFIDLRDHYGITQIVADPDSPAFKVAETVRGEWVIRVDGEVKARADDAVNTNLPTGEVEIFATEIEVLSPAKELPLPVFGEPDYPEDIRLKYRFLDLRRETLHKNIMSRTKIIAAMRRRMTEIGFNEFSTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLEMSFVTQEEVWETMEPVMRGIFEEFAEGKPVTKVFRRIAYDDAIRTYGSDKPDLRNPIEMQAVTDHFAGSGFKVFANMIANDAKVEVWAIPAKTGGSRAFCDRMNSWAQSEGQPGLGYIFWRKEGDKLEGAGPIAKNIGEERTEAIRKQMGLEDGDACFFVAGLPSKFYKFAGDARTRAGEELNLVDRDRFELAWIIDFPFYEWDEDNKKIDFAHNPFSLPQGGMDALENMDPLEIKAYQYDLVCNGFEIASGSIRNQLPEVMVKAFEKVGLSQQDVEERFGGLYRAFQYGAPPHGGMAAGIDRVIMLLVGAKNLREISLFPMNQQALDLLMGAPSEVSPAQLRDLHVRLAPVQKS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OXLA_TRIPP
Sequence: MNVFFMFSLLFLAALGSCADDRNPLEECFRETDYEEFLEIARXXXXTSNPKHVVRVGAGMSGLSAAYVLAGAGHQVTVLEASERPGGRXXXXXXXXEGWYANLGPMRXXXXXXXXXXXXXKFGLNLNEFSQENDNAWYFIKXXXXXXXXXXDPGLLKYPVKPSEAGKSAGQLYEESLGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFDEIVDGMDKLPTSMYQAIXXXXXXXXXXXXXXXXXXKVTVTYQTPAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIFLTCTKKFWEDDGIHGGKSTTDLPSRXXXXXXXXXXXXXXVIIAYGIGDDANFFQALDFKDCADIVFNDLSLIHQLPKEEIPSFCYPSMIQKXXXXXXXXXXITTFFTPYQFQHFSEAXXXXXXXIYFAGEYTAQAHGWIDSTIK
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:29890640).  Shows activity on L-Leu (PubMed:29890640).  Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, antibacterial and antiparasitic activities, as well as regulation of platelet aggregation (By similarity).  When tested on SW480 and SW620 human colon cancer cells, shows inhibition of cell proliferation, and induction of apoptosis, which is probably a consequence of the increased caspase-3 activity and the decreased Bcl-2 expression (PubMed:29890640).
What are the official names of this protein?
L-amino oxidase, CP-LAAO, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CMOA_TRIL1
Sequence: MTKKTDALYAAPLHDIIDFQFDERVVAVFPDMIQRSVPGYGMIIANIGVIAARYAQPGSHCYDLGCSLGAATLAMRQRITAPDCDIIAVDNSPAMIERARELLSLDTGLYIPVTLLCSDLQEVTIENASVVVLNFTLQFIPPPQRLALMQRIYAGLNPGGILILSEKIAFSKPEQQQLHIELHHDFKRANGYSDLEISQKRSALENVMIPETVAVHQKRLQTAGFSCAELWFQCFNFASLVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: PSD3A_ARATH
Sequence: MTQDVEMKDNNTPSQSIISSSTSTMQNLKEIAALIDTGSYTKEVRRIARAVRLTIGLRQKLTGSVLSSFLDFALVPGSEAHSRLSSFVPKGDEHDMEVDTASSATQAAPSKHLPAELEIYCYFIVLLFLIDQKKYNEAKACSSASIARLKNVNRRTIDVIASRLYFYYSLSYEQTGDLAEIRGTLLALHHSATLRHDELGQETLLNLLLRNYLHYNLYDQAEKLRSKAPRFEAHSNQQFCRYLFYLGKIRTIQLEYTDAKESLLQAARKAPIAALGFRIQCNKWAILVRLLLGEIPERSIFTQKGMEKALRPYFELTNAVRIGDLELFRTVQEKFLDTFAQDRTHNLIVRLRHNVIRTGLRNISISYSRISLPDVAKKLRLNSENPVADAESIVAKAIRDGAIDATIDHKNGCMVSKETGDIYSTNEPQTAFNSRIAFCLNMHNEAVRALRFPPNTHKEKESDEKRRERKQQEEELAKHMAEEDDDDF
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 3 homolog A, 26S proteasome regulatory subunit RPN3a, AtRPN3a, 26S proteasome regulatory subunit S3 homolog A, Protein EMBRYO DEFECTIVE 2719, Protein HAPLESS 15.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S3 family.
Protein: MUTS_CALBD
Sequence: MQELTPMMQQYMEIKQKVKDCILFFRLGDFYEMFFEDAIVASKELEIALTSRDCGNNEKAPMCGVPYHSATSYIAKLIEKGYKVAICEQVEDPKLAKGIVKREITRIITPGTFIDDNISTANNFICCISKDRSEFALTFVDVSTGEMYSCLLEEDLQKLVNEIGKYSPSEILISNIEDELYEFLKKNCTSFVQMIEFVDLQKCHEIIENQINVGKIDEKLILSVGNLLKYLTETQKISFDYIRRFEFYRVQNYLQIDINTKRNLELTESIIQRSRKNSLLGILDQTKTSMGSRLLKKWIERPLIDIIEINKRLDSVEELKSNYSTLVQVEELLSRMYDIERLSSKFAYKNVNAKDLLSLKKSIEVLPTLKQFLSSFDSELLKEIYEGLDTLEDIYALIDSSINEDAPVSLKEGGIIKEGFNEEVDRLRNISKNSKELLVEYEEKERNLTGIKNLRIGYNKVFGYYIEVTKSNYSLVPDRYIRKQTLANAERYITEELKKLEDEILGADQKLIELEYQLFCEIRDRIEAQIERIQKTASNIANLDVLCSFARIAIDNEYVRPNVYLGDRIYIKNGRHPVVEKMIGRGNFIPNDTELDQAENRVLIITGPNMAGKSTYMRQVALIVIMAQMGCFVPADEAHIGVVDKIFSRIGASDDISSGQSTFMVEMSEVANILKNATPKSLIIFDEVGRGTSTYDGLSIAWAVLEYVADKSKIGAKTLFATHYHELTELEERIPGVKNYRVDVKEEGKNIIFLRKIVRGGCDSSYGIHVARLAGIPEEVLKRAEEILKQLEEADINRKNIRKLRREIKKEFTEQIDFFSYKKEEIIDKIEKLDILNITPIQALNILSELKHEIIKAKERQLI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: NRDR_BART1
Sequence: MRCPYCQYEDTQVKDSRPAEEGAVIRRRRVCSVCGGRFTTFERVQLRELLITKKNGRCEPFDRDKLMRSVDVAVRKRNIDPDRIEQAISGIVRQLESLGEPEIASEKIGHLVMEALKGIDDIAYIRFASVYRDFRNASDFHDIIDELSKGIADTESRFDE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: THIL_MYCTU
Sequence: MTTKDHSLATESPTLQQLGEFAVIDRLVRGRRQPATVLLGPGDDAALVSAGDGRTVVSTDMLVQDSHFRLDWSTPQDVGRKAIAQNAADIEAMGARATAFVVGFGAPAETPAAQASALVDGMWEEAGRIGAGIVGGDLVSCRQWVVSVTAIGDLDGRAPVLRSGAKAGSVLAVVGELGRSAAGYALWCNGIEDFAELRRRHLVPQPPYGHGAAAAAVGAQAMIDVSDGLLADLRHIAEASGVRIDLSAAALAADRDALTAAATALGTDPWPWVLSGGEDHALVACFVGPVPAGWRTIGRVLDGPARVLVDGEEWTGYAGWQSFGEPDNQGSLG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
What are the official names of this protein?
Thiamine-monophosphate kinase, TMP kinase, Thiamine-phosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-monophosphate kinase family.
Protein: PURT_BURTA
Sequence: MQIGQRLGTPLSPSATRVMLLGAGELGKEVIIALQRLGVEVIAVDRYPNAPGHQVAHRAHVIDMTDPDALRALVDAERAHLVVPEIEAIATDALAEIEAAGVAEVIPTARATQLTMNREGIRRLAAEELGLPTSPYAFAQSFDAFRAAVAQIGFPCVVKPVMSSSGKGQSVVRSDADVEPAWQYAMAGGRVNHGRVIVEGFVQFDYEITQLTVRAIDPASLKTRTYFCEPIGHVQVAGDYVESWQPQPMSAKALERSRDIAHRVTSALGGRGIFGVELFVRGDDVWFSEVSPRPHDTGLVTLASQRQSEFELHARAILGLPVEPALATPAASAVIYGGLDEAGIAFEGVRDALAVPGADLRLFGKPESFAKRRMGVALATGANVDEARERAKRAAAAVRPVSAR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: MMP1A_MOUSE
Sequence: MPSLPLLLLLWAASSYSFPVFHNGDRQNVETVWKYLENYYNLGKNMQAKNVNGKEMMAEKLRQMQQLFGLKVTGNSDPETLRAMKKPRCGVPDVAPYAITHNNPRWTKTHLTYSILNYTPYLPKAVVEDAIARAFRVWSDVTPLTFQRVFEEEGDIVLSFHRGDHGDNNPFDGPNYKLAHTFQPGPGLGGDVHYDLDETWTNSSENFNLFYVTAHELGHSLGLTHSSDIGALMFPSYTWYTEDFVLNQDDINRIQDLYGPSPNPIQPTGATTPHPCNGDLTFDAITTFRGEVFFFKGRFYIRVNRFMPEPELNLIGILWPNLPVKLDAAYEASMIDQVRYFKGSKVWAVQEQSVLRGFPRDIHSFFGFPSNVTHIDAAVCEEETGKTYFFVDHMYWRYDENTQSMDPGYPRLTAEDFPGIDDKVDDVFQKGENFYFFHQSVQHRFNLQIRRVDDSRDSSTWFNC
What is the function of this protein?
Cleaves collagens of types I, II, and III at one site in the helical domain.  Also cleaves collagens of types VII and X (By similarity).  Able to degrade synthetic peptides and type I and II fibrillar collagen.
What are the official names of this protein?
Interstitial collagenase A, Matrix metalloproteinase-1a, MMP-1a, Mcol-A.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: FRDC_YERPE
Sequence: MTTKRKAYVRTMAPNWWQQLGFYRFYMLREGTSIPAVWFSVLLIYGVFALKSGPAGWEGFVSFLQNPLVLFLNILTLFAALLHTKTWFELAPKAVNIIVKSEKMGPEPMIKALWVVTVVASAIILAVALL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPB_TREPA
Sequence: MNTDRYTVKASEALNDAISLAEAENHGQVEEEHLLHALLSQKDGIISPLIEKIGAKPDFLYDELLQCLRRKPRVTGPAAQTRCAPTLSKACARAERLALKNQDEYVSCEHLLLAISETDSNTARLLHSQGITSKTISAALKDIRGSKRVTSQDPESTFQCLEKYCRDLTTLAREEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSGDVPESLKGKRLLSLDLGALVAGAKFRGEFEERLKAVIEAVQKSDGGVILFIDELHTLVGAGASEGSMDASNLLKPALARGELRSIGATTLNEYRKYIEKDAALERRFQQVYCVQPTVEDTIAILRGLQEKYEVHHGVRIKDEALVAATVLSDRYITNRFLPDKAIDLVDEAASRLKMEIESQPVELDQVERKILQLNIEKASLLKESDPASKERLEKLEKELAGFLERRAAMQVQWQNEKGRIEESRRYKEELERLRIEETMFSREGDLNKAAELRYGKIPELEKKIMLLTAEVEKKSGLEGQLLREEVCEEDIAKIISMWTGIPVSKMMASEQQKYLQLESVLMQRVVGQDEAVRVISDAIRRNKAGLSDTRRPLGSFLCVGPTGVGKTELARTLADFLFNDERALTRIDMSEYMEKHAISRLIGAPPGYVGYDEGGQLTEAVRRRPYSVLLFDEVEKAHQDVFNIFLQILDDGRLTDGQGRVVDFRNTIIIMTSNIGSEHILSARESRTHTSDLPVPETQSTEEQTLPEQIRGLLHTYFRPEFLNRIDEVLIFKRLTRKHIRLITDIQLQMVVERLESRHIKLRVRDAAKAYLAERGYDDTFGARPLKRAIQTELENALAREILSGRFRGGSTIVVDMCKDALCFTEQTS
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_DESRM
Sequence: MQVVLLQDVVKLGKKGDIVNVSEGYARNFLYPKNLAAPATESKLKELKTQKQTQAAKKQKEEAEAKALAAKINGLTVALKVKVGDAGRLFGAISNKDIADGLKSQHGYSIDKKKIVLKEPIKNLGTYKITLKIHPVAQADINVEVASMD
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: UBID_YERPA
Sequence: MISMKYRDLRDFLSLLEQRGELKRISQPIDPYLEMTEIADRTLRAGGPALLFENPKGYSMPVLCNLFGTAKRVAMGMGQEDVSALRDVGKLLAFLKEPDPPKGFRDLFDKLPKFKQVLNMPTKRLNSAPCQEQVWQGEDVDLSRIPVMHCWPEDAAPLVSWGLTITRGPHKERQNLGIYRQQVLGKNKLIMRWLSHRGGALDYQEWCEAHPGERFPVAVALGADPATILAAVTPVPDTLSEYAFAGLLRGHKTEVVKCLSNDLEVPASAEIVLEGYIEQGDMAPEGPYGDHTGYYNEIDNFPVFTVTHITQRQDAIYHSTYTGRPPDEPAVMGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGIWSFLRQFMYTKFVIVCDDDINARDWNDVIWAITTRMDPSRDTVLIENTPIDYLDFASPVSGLGSKMGLDATNKWPAETPREWGRPIKMDEDVRARIDALWDELAIFSDKDAKR
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYRE_AGRRK
Sequence: MTQMTFSDRAVMAELVAKMLWEIKAVHFSADKPYKLASGMASPVYIDCRKLISYPRVRSTVMDFAASLIMRDAGFEQFDCVAGGETAGIPFAAFLAERLNLPMIYVRKQPKGHGRNSQIEGHMPDGARVLVIEDLTTAGGSMFTFIDAIRAAGGIVDHGMALFYYGIFPEAEARFANGKVRLHHIATWRNVLAVAKEQKLFDDKTLEEVEAFLNAPLAWSGRNGGVAELATK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: LEP_SALTY
Sequence: MANMFALILVIATLVTGILWCVDKFVFAPKRRARQAAAQTASGDALDNATLNKVAPKPGWLETGASVFPVLAIVLIVRSFLYEPFQIPSGSMMPTLLIGDFILVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKITYDPVAKEVTIQPGCSSGQACENALPVTYSNVEPSDFVQTFARRNGGEATSGFFEVPLNETKENGIRLTERKETLGDVTHRILMVPIAQDQLGMYYQQPGQPLATWVVPPGQYFMMGDNRDNSADSRYWGFVPEANLVGKAVAIWMSFDKQEGEWPTGVRLSRIGGIH
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FKBP2_SPIOL
Sequence: AGLPPEEKPKLCDAACE
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Probable FKBP-type peptidyl-prolyl cis-trans isomerase 2, chloroplastic, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.