PharMolix/UniProtQA huggingface dataset:
Protein: PHT21_ARATH
Sequence: MTLPYRFSSVRNHSLLLKTSHLCTPRSALGCCFSPKESPFFRKNTAQFLSPQKHTSLPLKLVCPLASFSSYADSEGEEQHHADQPIQNPHESSTVSNESDGKGNAEATGDFSGMAQAFHISSTTARAISIVIAFSALTLPIFMKSLGQGLALKTKLLSYATLLFGFYMAWNIGANDVANAMGTSVGSGALTIRQAVMTAAVLEFSGALLMGTHVTSTMQKGILMANVFQGKDMLLFAGLLSSLAAAGTWLQVASYYGWPVSTTHCIVGSMVGFGLVYGGAGAVFWSSLAKVASSWVISPILGALVSFLVYKCIRRFVYSAPNPGQAAAAAAPVAVFVGVASISSAALPLSKIFPIALSQALACGVAGAIVFDRIIRKQLGHLLAKTKSPETSQNQPKTIGFLSDIAGPTGTQLEIVYGIFGYMQVLSACFMSFAHGGNDVSNAIGPLAAALSILQNGAAAGGAEIVIPMDVLAWGGFGIVAGLTMWGYRVIATIGKKITELTPTRGFAAEFAAASVVLFASKLGLPISATHTLVGAVMGVGFARGLNSVRAETVREIVASWLVTIPVGATLAVIYTWIFTKILSFVL
What is the function of this protein?
Low affinity H(+)/Pi chloroplastic cotransporter.  Involved in inorganic phosphate (orthophosphate, Pi) uptake in green parts of plants in Pi-sufficient conditions.  Required for Pi retranslocation during Pi deprivation.
What are the official names of this protein?
Inorganic phosphate transporter 2-1, chloroplastic, H(+)/Pi cotransporter, AtPht2;1.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20.2) family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: LAMC1_DROME
Sequence: MKRSRWSHSGSSTARLLLIGVLFASCSTAILGAQRPPINSAGGHELRGTTFMPALECYDPYGRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFCIQTMNQNHKNCEFCKYNDHNPSFLTDLHDPQSPTWWQSETMFEGIQHPNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAHALCTSEYSDISPLRDGEIAFSTLEGRPSGINFERSGELQEWVTATDIRITLDRLNTFGDELFGDSQVLKSYFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRTGHGGHCLDCRENRDGPNCERCKENFYMRDDGYCVNCACDPVGSRSLQCNSHGKCQCKPGVTGDKCDRCDNNYYQFGPHGCQQCGCDSGGSHQNTPACDTETGICFCKENVEGRRCNECKPGFFNLDKNNRFGCTPCFCYGHTSECMTAPGYSIVSVTSNFNKFKERWTAADLNQREVDIKYNQYSRSIGTTAQGNEHVYFQAPDRFLGDQRASYNRDLKFKLQLVGQVANTGVSDVILEGAGSRISLPIFAQGNGIPDQGVKEYTFRLHEHHDYQWQPSQSARGFLSILSNLTAIKIRATYSVQGEAILDDVELQTAHRGAAGHPATWIEQCTCPEGYLGQFCESCAPGYRHSPARGGPFMPCIPCDCHGHADICDSETGRCICQHNTHGDNCDQCAKGFYGNALGGTPNDCKRCPCPNDGACLQINEDTVICTECPKGYFGSRCEQCSDGFFGDPTGLLGEVQTCKSCDCNGNVDPNAVGNCNRTTGECLKCIHNTAGEHCDQCLSGHFGDPLALPHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGECQPGYFNIRSGNGCENCLCDPVGSYNSTCDRYSGQCHCRPGVMGQRCDQCENYFYGFSSEGCKPCECDESGSKGFQCDQNGQCPCNDNVEGRRCDRCKENKYDRHRGCIDCPDCYNLVQDAADLHRAKLFNLSQTLDEIARTPVTNDDEFEAKLKAVQEKVAVLAQDARDNSGDGGQTYAEVIDDLHKHLDSVREHLVSADKFQADANGEIDRARQNYTILDQITENAKKELQQALDLLNDEGAQALARAKEKSVEFGQQSEQISDISREARALADKLESEAQFDLKNAKDAKDAVEKAHQLAKSAIDLQLKIGTELRSEVGLELSHVKQSLGTVVQTSKEALRKANEVYDTALTLLNDVNRQTQPEIDISQLKKDAVAANERADELLKQITELSNSNGELFADFETEQELTEALLKRAEQQQLEDIELLERAKAAHDKATKAVEQGDNTLKEANNTYEKLAGFQSDVQRSSESAEKALQTVPNIEKEIQNAESLISQAEEALDGANKNANEAKKNAQEAQLKYAEQASKDAELIRRKANETKVAARNLREEADQLNHRVKLTEMDIFKLEESSTKDDNLVDDAKRKVGQAKADTQEAQKQIEKANADLTAIKDELENLKDINTGDLDRLENRLATVEGEINRVNLTGRIEKYREQRTIQKNLIDKYDAELRELKDEVQNIGLISKALPDSCFSRNRLEP
What is the function of this protein?
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
What are the official names of this protein?
Laminin subunit gamma-1, Laminin B2 chain.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Protein: NRDR_RHORT
Sequence: MRCPFCGNGDTQVKDSRPTEDSAAIRRRRFCPACNSRFTTFERVQLRDLVIVKKDGQRSAFDRDKLARSIRIACRKRPVDEDSIERIVNGIQRRLESSGDTEINSKAVGELVMEGLRGLDPVAYVRFASVYRNFREAKDFEDFVETLGGSAD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: HAUS4_MOUSE
Sequence: MASGDFCAPGEGVEMLLQVCGKQFPPCALTEEDLIQNPRFSKLLLSLSQHVDESGLSLTLAKEQAQAWSEVRHRKTAWLRYEILQRVIQELLVDYYVKAQDTNLTSEDKKFHETLEQRLLVTELTQLSGPGQETELPPLLGLERTDLLELMPPSQDFVWMKARLQLEVEEQLKRKCFTLLCYHDPSSDTDGDTLKAAKVWTLTEVLVREKQQCLEAKSQQKEQLVLLEKKRTTYSQVLLRCLALLQRLLQEHRLQTKSELDRINAQYLELKCSAMILRLRMEELKVLSDTYSAEKVEMHRLIRDRLEGAIRLQEQDLEKSRLVLHTYEALGEDFESLVREYTQLRLAADNKRWALQELSKAQR
What is the function of this protein?
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
What are the official names of this protein?
HAUS augmin-like complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the HAUS4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules.
Protein: JUND_CHICK
Sequence: METPFYHDDVLSGLGSGFAPTSGSSGLLLPFPGGSMMKKDALGLALPEQVAAALKAPGAAAAAAAAAGGEATAGLLGSPEMGMLKLSSPELERLIIQSNGLVTTTPTSGQFLYPKAAASEEQEFAEGFVKALEDLHKQNQLGGGGGPNGGAAAAGGGGGGGGGGGGELPAPGLAPEPPVYANLSTYPAVSYAAEPGPFAAPPPRLPPPPPPPLKDEPQIVPEVPSFGESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKSLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQHQVPAY
What are the official names of this protein?
Transcription factor JunD, Transcription factor AP-1 subunit JunD.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Jun subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM1_CHLTR
Sequence: MVREGEERIGNRVSLGVIGVSYRETTLQQREQVLHILQQAQGSFRPEVFQEERDYVLLATCHRVELYSVAPAELFDSLAQEIELLGVSPYFYRNQDCFAHLFCVAGGLDSLVLGETEIQGQVKRAYLQAAREQKLSFALHFLFQKALKEGKVFRAKGGAPYAEITIPILVDQELRRRQIDKKASLLFIGYSEINRSVAYHLQRQGFSCITFCSRQQLPTLSMRQVVREELCFQDPYRVVFLGSSELQYALPHSLWESIWDIPDRIVFDFAVPRALPSHTVFPHRYVDMDQISDWLREHRKEVNSAHLHSLREVAYRYWNSLNQRLERRDCVGANA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: LDRA_ECOLI
Sequence: MTLAQFAMIFWHDLAAPILAGIITAAIVSWWRNRK
What is the function of this protein?
Toxic component of a type I toxin-antitoxin (TA) system.  Inhibits ATP synthesis possibly due to its insertion in the cell inner membrane, ATP levels drop over 50% 2 minutes after induction (PubMed:24513967).  Overexpression is toxic leading to cell death, it inhibits cell growth within 30 minutes; C-terminally tagged versions of the protein are toxic while N-terminally tagged versions are not (PubMed:24513967).
What are the official names of this protein?
Small toxic polypeptide LdrA.
What is the protein family that this protein belongs to?
Belongs to the Ldr toxic peptide family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TIPA_STRCO
Sequence: MSYSVGQVAGFAGVTVRTLHHYDDIGLLVPSERSHAGHRRYSDADLDRLQQILFYRELGFPLDEVAALLDDPAADPRAHLRRQHELLSARIGKLQKMAAAVEQAMEARSMGINLTPEEKFEVFGDFDPDQYEEEVRERWGNTDAYRQSKEKTASYTKEDWQRIQDEADELTRRFVALMDAGEPADSEGAMDAAEDHRQGIARNHYDCGYEMHTCLGEMYVSDERFTRNIDAAKPGLAAYMRDAILANAVRHTP
What is the function of this protein?
Transcriptional activator.  Is activated when bound to the antibiotic thiostrepton (By similarity).
What are the official names of this protein?
HTH-type transcriptional activator TipA.
Protein: PDXH_PELUB
Sequence: MNQKNSLGLNKCFLDKIDPIDLFEVWMNEAKKTELNDPNALALATSDQNNFPSIRMVLLKDFNKDGFVFYTNLNSQKGNELKNNPKASMCFHWKSLLRQVRINGMVQKVSNKVADEYYSSRGYESRIGAWASKQSTVINNRDELLNSIEEYKKKYSNKNDVPRPEHWSGWNLIPTSIEFWLDGESRIHERLKYTKDTEGNWVKSLLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: HIS1_LEPBP
Sequence: MLTLALPKGRLAEETALLLLSKGWLKNLPSEGSKELTYVSEDKRIRLLFVRSQDVCTYVEEAAADVGIVGWDIIREGGFDLIAPVDLKLGACRLSLASFPDFDLFAKRSKVRVATKYPNLTREYFFSKGISCEIIKLYGSIELAPIVGLSDCIVDLVSTGGTLKANGLKEFESILFSTARLVSNRSSFYHKHAELRSLIESLEN
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_THENE
Sequence: MAEFFPEIPKVQFEGKESTNPLAFKFYDPEEIIDGKPLKDHLKFSVAFWHTFVNEGRDPFGDPTADRPWNRYTDPMDKAFARVDALFEFCEKLNIEYFCFHDRDIAPEGKTLRETNKILDKVVERIKERMKDSNVKLLWGTANLFSHPRYMHGAATTCSADVFAYAAAQVKKALEITKELGGEGYVFWGGREGYETLLNTDLGFELENLARFLRMAVDYAKRIGFTGQFLIEPKPKEPTKHQYDFDVATAYAFLKSHGLDEYFKFNIEANHATLAGHTFQHELRMARILGKLGSIDANQGDLLLGWDTDQFPTNVYDTTLAMYEVIKAGGFTKGGLNFDAKVRRASYKVEDLFIGHIAGMDTFALGFKVAYKLVKDGVLDKFIEEKYRSFREGIGRDIVEGKVDFEKLEEYIIDKETIELPSGKQEYLESLINSYIVKTILELR
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFH_ARCFU
Sequence: MKSIRMLMVMLALDDLLKNPYETFRIADELRRELVGDTVTYVVNRNINFTDICINDCKFCSFRNRKKYLLSLDEIKQKVEEAVEFGCTELCIQGGLLPDADLDFYLSILQAVRDVDKKIHIHAFSPMEVVHAARNSGMTVEEVLKELKKEGLGSMPGTAAEILDDSIRALICPRKLKTAEWVEVIKTAHRVGIPTTATIMYGHIDTWEHRINHLLLIKKIQQETGGITELIPLPFMSKNNELGRYAKGSSGFDDLLMIAIARILLYPEIKNIQASWVKMGQKLAQAALHVGANDLGGTLMEENISKSAGATSGEFMHPEELRELIKIAGRVPKQRDTLYNILD
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: RADB_HALSA
Sequence: MREDDTHLPTGCGALDELLGGGVERGTVTQLYGPPAAGKTNVALTTAVTTAAAGGLAVYVDTEGLSLARFQQLLEARATDPEAASANVIVSDAHDFDEQAQAVRDTADFADRADLIVVDSVTGFYRLARGGDDTTGDALRQVADQITHLLSLARKHDLAVVVTNQVFTDVDNDSDRARPLGGHTLAHWTGTVLRLDRFRGGTRRATLEKHRAKPDGEHAQFQITDGGIDAASADDY
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  May regulate the cleavage reactions of the branch-structured DNA.  Has a very weak ATPase activity that is not stimulated by DNA.  Binds DNA but does not promote DNA strands exchange (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RadB.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
Protein: TRMFO_THEM4
Sequence: MIVNIIGAGLAGVEVAWKLLNTGVKVRIFEQKPKKFSTVHKNPNFGELVCSNSLKSESLNNAEGILKAEMNILDSLVLKCAYRCRVPAGKALAVDRDKFSQCITEHILSFDNVEVIREEIKSIDLKEDEIWVVATGPTTDGEFANWLSNLTGGFLNFFDAVAPIISGDSIDFNKCFFADRYGKGTSDYINCPMTKEEYERFYKELINAEKIEMEDFDRKLLFERCQPIEEIAKSGEKSLLFGPLRPVGLIDPRTGKMPYAIIQLRKEDENGNMYNLVGFQTRLKWPQQKRIIRLIPGLENAEILRYGVMHRNTYIDSPKVLDEFLRHKKFQNLFFAGQITGVEGYVESAATGIFVGINILRFLEKKELVALPTKTMLGALLNYITTSKQLKPMYANFGLVDVKMGKKEKREKLHKICLEEMKKFLYMLK
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_LATSS
Sequence: MTKTESKQLEVLRFIHERVQDKGYPPTVREICEAVNLSSTSTVHGHLARLEKKGLLQKDPTKPRAIELTPAGLTAIGATPQKIPVLGVVTAGVPILAVEEATDYFPLPPSLQTEQDLFMLTIRGESMINAGILDGDEVIIRKQSTADNGDIVIAMTAEDEATCKRFFKEADHYRLQPENDTFEPIILNEVSILGKVVGLYRDRM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: YR011_MIMIV
Sequence: MSKIFRKFAKTEFIFRFNIIDHNVILYSLYLDIIPMDSSNNYKKKYKKYKRKYIDLKKQLNYNQIHNFYFVHSTTNFSNLRDILKSGVIYPGKFLRPDQQKLSVNSEDVFANIYFEDINNLTHLQDFSILLHPKIIYDCGMFFNKGWQGGGKGDIIINATDSPVQIAHKLNEIREFLKNPILPEKIREFNPFLHHEAFFNHPISLNNGNLIGIICNHCDGSFNDYITGETHKESLKIINNIINDKLYNNVKIITRNYPIPKLNELLH
What are the official names of this protein?
Uncharacterized protein R11.
Protein: URE1_AGRVS
Sequence: MPFKMSRAAYASMFGPTTGDKVRLADTELFIEVEKDFTHYGDEVKFGGGKVIRDGMGQSQATRVDGAVDTVITNALIVDHWGIVKADIGLKDGRIVAIGKAGNPDTQPGVNIIVGPGTEAIAGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASLPGALEEMVLGGACALKLHEDWGTTPGAVDCCLSVADDYDVQVMIHTDTLNESGFVEDSIGAIKGRTIHAFHTEGAGGGHAPDIIKICGQPNVIPSSTNPTRPYTINTLAEHLDMLMVCHHLSPSIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLPSETGENDNMRVKRYIAKYTINPAIAHGLSHEIGSIEIGKRADLVIWNPAFFGVKPDMVLLGGSIAAAPMGDPNASIPTPQPVHYRHMFGAYGKARTNSSVTFVSQASLDVGLAARLGVSKQLLAVKNTRGGISKASMIHNSLTPHIEVDPETYEVRADGELLTCEPATVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPM1_MOUSE
Sequence: MGSMRKMSSSFKRGSIKSSTSGSQKGQKAWIEKTFCKRECIFVIPSTKDPNRCCCGQLTNQHIPPLPSGAPSTTGEDTKQADTQSGKWSVSKHTQSYPTDSYGILEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQSFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVVSHVGDALKDHSSKSRGRLCAIGIAPWGMVENKEDLIGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRQLEKHISLQKINTRLGQGVPVVGLVVEGGPNVVSIVLEYLKEDPPVPVVVCDGSGRASDILSFAHKYCDEGGVINESLRDQLLVTIQKTFNYSKSQSYQLFAIIMECMKKKELVTVFRMGSEGQQDVEMAILTALLKGTNASAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPVDTKATEKEKKPPTATTKGRGKGKGKKKGKVKEEVEEETDPRKLELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKSFRTLYNNLFGPKRPKALKLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEECMAKALVACKLYKAMAHESSESELVDDISQDLDNNSKDFGQLAVELLDQSYKHDEQVAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILIPPTILFLEFRTYDDFSYQTSKENEDGKEKEEENVDANADAGSRKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWPSPQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISMFMVGAILRLQSQPYMGYGRVIYCVDIILWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKKLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERENFMKTSLQTVDLRLSQLEELSGRMVSALENLAGIDRSDLIQARSRASSECEATYLLRQSSINSADGYSLYRYHFNGEELLFEEPALSTSPGTAFRKKTYSFRVKDEDAKSHLDQPSNLHHTPGPSPPATPGRSRLALEGPLSTELRPGSDPGISAGEFDPRADFKSTEAAPSLNAAGVTGTQLTVESTDSHPLRESKLVRYYPGDPNTYKTMKSRSFVYTEGRKLVRGLSNWSAEYSSIMDQAWNATEWRCQVQRITRSRSTDIPYIVSEAASQDELEDEHRGSLLDPQISRSALTVSDRPEKENLLSVKPHQTLGFPCLRSRSLHGRPRSAEPAPSKLDRAGHASSTSNLAVMSVVPEGQNTQQEKRSAETEC
What is the function of this protein?
Forms nonselective divalent cation-conducting channels which mediate the influx of Na(2+), Ca(2+), Mg(2+), Mn(2+), Ba(2+), and Ni(2+) into the cytoplasm, leading to membrane depolarization (By similarity).  Impermeable to zinc ions (By similarity).  In addition, forms heteromultimeric ion channels with TRPM3 which are permeable for calcium and zinc ions (By similarity).  Essential for the depolarizing photoresponse of retinal ON bipolar cells.  It is part of the GRM6 signaling cascade.  Calcium channel which may play a role in metastasis suppression.  May act as a spontaneously active, calcium-permeable plasma membrane channel.
What are the official names of this protein?
Transient receptor potential cation channel subfamily M member 1, Long transient receptor potential channel 1, LTrpC1, Melastatin-1.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, axon.
Protein: MNMG_FINM2
Sequence: MDRLYYENPYDVVVVGAGHAGCEAALATARLGLKTAIMSISLDSVADLPCNPNIGGTGKGHLVKEVDALGGEMGLVIDKTYIQSRMLNTSKGPAVHSLRVQADKRKYHDEMKSVLENTENLDLIEAEVVDIEVEDNKIKSITTAQGAIFPTRAVILATGTYLKGLVMMGEYTYESGPHGMKSSKKLSYSLKNLGIELRRFKTGTPARVHRDSLNYEVMTVQPGDDDVIPFSFLNDGKDISKKQEHCYLTYTTLKTKQIIEDNLERSPMYAGIVKGVGPRYCPSIEDKIVRFPDRDEHQVFVEPEGLSTKEMYIQGVSSTLPEEVQKEMYKTIIGFENVRFMRSAYGIEYDCIDPTILKRTLEHLEINNLFFAGQINGSSGYEEAAGQGIIAGINAAMNLLGKEPFVLDRSDAYIGVLIDDLVTKGTNEPYRMMTSRCEYRLTLRQDNADLRLTERAHEIGLATDERYEKMLHKKKTIDEEIERLKSIMVTPTEETNEKLRNLGSSELKTGITLLDLIKRPELTYDKTEEFDAERTELPRYLRLQVETHIKYEGYIAKQMSQIKQFKKLENRKLDMIEDYKEVMGLSNEAVQKLNDIKPESLGQASRISGVSPSDINVLLIYMETRKK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCP4_MOUSE
Sequence: MSERQSAGATNGKDKTSGDNDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS
What is the function of this protein?
Functions as a modulator of calcium-binding by calmodulin.  Thereby, regulates calmodulin activity and the different processes it controls.  For instance, may play a role in neuronal differentiation through activation of calmodulin-dependent kinase signaling pathways.
What are the official names of this protein?
Calmodulin regulator protein PCP4, Brain-specific antigen PCP-4, Brain-specific polypeptide PEP-19, Purkinje cell protein 4.
What is the protein family that this protein belongs to?
Belongs to the PCP4 family.
Protein: CLPP_BURCH
Sequence: MITRAELLDMLASNAPQGFEAQALGLVPIVVETSGRGERSYDIYSRLLKERLVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSPGGSVSAGMAIYDTMQFIKPDVSTLCMGLAASMGAFLLASGAKGKRFALPNSRVMIHQPLGGARGQASDIEIQAREILYLKERLNNLLAQHTGQDVERIARDTDRDNFMSSEDAKAYGLIDQVLLKRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU12_BACP2
Sequence: MFNHKKYEKKYFLPPNLTYDWVKNETLESAPIWCSVDLRDGNQALPIPMNLEEKLEMFQLLVEIGFKEIEIAFPAASDTEFRLLRTLIDHHMIPDDVTIMVITQAREHIIRRTFEAIKGVPKAIVHLYNSTSEAQRRQVFKKTKDEVKQMAMDGAILVKELAEKTESDIYFQYSPESFPGTEVDYALDICNSVLDIWKPTPNHKAIINIPTTVEYSMPHIFASQIEYIHKNLSYRDSVTLSVHPHNDRGSGVSDAEFGVLAGAERVEGTLFGIGERTGNVDLITLAMNMYSQGYDPKLNFNNLEAIRKQYEKLTNITVHERQPYSGEMVFTAFSGSHQDAISKGMKYRKEHHVDKWDVPYIPVDPVDLGRNYQTDVIRINSQSGKGGIGYILETNYGIQLPYQMNEAMGYEAKKVSDQSNRELSVEEIYHVFEKQYVDFHPHFQLLDYQFHKGEKQEVTLTLLRDHQQIDIQGTGTGSLDAISNALKAYFHLEYDLEVYEQNSLGKDSQAKACAQIGISHQGKMHWGAGIDKDIIEATVKALVVAVNRLEVWM
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: DER_THEPX
Sequence: MAGAMVSIVGRPNVGKSTLFNKIMGKRISIVEDKPGVTRDRIYGNAEWLDKKFILVDTGGLDPNAEDILFSKVRLQVEAAIDTSDVILFLVDAKEGLMPEDEEIANILRRAKKEVILVCNKVDSFKEMPPTYYDFFSLGLGNPIPISASNGLGIGELLDEVVKRLPQEELEYTEETIKIAVIGKPNVGKSSLVNKILGEERVIVSNIPGTTRDAIDTPFSKDGKNYVLIDTAGIRRKSRISESIERYSVLRALAAIERSDICLLMIDATEGPTEQDTKIAGYAFENGKGIIIVVNKWDAIKKDNNTVNEYTKMVREKLSFISFAPILFISAKTGQRVHRVLETVDKVWEEYNKRITTGLLNNVLNEAILMFPPPADKGKPLKVYYTSQVGIKPPSFVVFVNEPELMHFSYLRFIENTLRQNFGFEGVPIVISTKKRGEN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: NUOK_RHILW
Sequence: MVIGLSHYLTVSAILFTLGVFGIFLNRKNVIVILMSVELILLAVNINMVAFSSFLNDIVGQVFALFILTVAAAEAAIGLAILVVFYRNRGSIAVEDVNMMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROA_SALNS
Sequence: MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGGALRAPGALELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFTGGDIEVDGSVSSQFLTALLMTAPLAPEDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVEGDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARMSTPA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_SHIBS
Sequence: MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAVSEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVIDGSVRGRLERLADVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.