PharMolix/UniProtQA huggingface dataset:
Protein: SPT5H_CAEEL
Sequence: MSSDESDAASNKEEDTTLSDDDGSDVEIKNSKKDRKRKLASESEKSGSDDDDDDDDDEDENVTSKKSKKQKRKNKAPSGRDFLAWDVEVDDEDEDDDNDYDDEDDPSMNAMNEREEAERAMKEMELSQRNRDRYKFQNMTEDEVQKYFENKYKGDKNDSQYDDEDSAMDDISKNSHLPSTKDPNLWIVKCRMGEEKLVAMHLMRKCLAVEHTNEPFQIKSVVVKEGLKGMIYIEAFKQSHVMSAIEGFSALNQFTITMVPIKDMVDVLRVVKDIPQLKLGSYVRLKRTMYKDDLAVVDLVDIAQNRVNLKLIPRVDYQKRRGAMRTDADKNYKLKRRPMPKLFDQDTIKEVGGEIVTDGDFLVFEGNHFRRGFLYKYFPINAIQADGVKPTLGELEKFQESSDDLKRELETASLKDTENPFVPGDIVEVKAGELVNLRGKVMTVDGTKVVMMPDQEDLKEAITLNAHELRKYFKEGDHAKVISGRYEGHTGLIVRVKDSTAIVLSDLGMEELKVRVRDLQLCADVTTGVDSLGQFQYHDLVQLDHTGNVGVIVRLEKEHLEVLNMHGVVNRIKPQAIIAKKDVRFAKVLDSQNNSIEAKDLVKVIGGPNAKERETDEDPVGEVLYAFRGTVFVYSRKVTKNGGVLVCKPKQLILQGAKKTTSTPMVSRMASPNPMASPRHSSGGMTPRSPQDGMSSRGSSGGQTPRQGGGGGRGGHFGTANQQKVRRDLTLIGKNVRIIKGPMKGHFGIVRDATEDTVRVELHTQCRTISVDRARVMVVGDTGITAGSGGGSSFYSSSKTPMRDSGKTPMYGSKTPMYGAQTPMYGSMTPAYDGGRTPAYGEGGRTPAYGSKTPAYGDLDEHSSSRTPAYGNDSSRTPAYGSADGARTPAYGSTEGGRTPAYGSMDNSRTPAYDDSGRTPGYESMPSRTPNYDSSSKTPAYPESEHSARTPAYNNDYDIPLSPAYEPDAPEAYDNAPARTPAFVSRTPGYDTYENSSPTYEPDAATKVEEDIGDTSSPTYDSPPHSYVVPTPGAMLNPATPGAYHVDTPGFAAPMTPGSGGAYDQYVAPSPFAGYDSNNYNNADGAIEQIPDHFLAQGVWIVQNLCVQIKDHEGRFNGREAIIKDVTDGKVDVYMPDHKCNLEVDFDQLTPMKPQPGDDARVIFGQDAGHSGQLVSMDGFEAVIRSQEDMSDMRVINIGLCCKMHSET
What is the function of this protein?
May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.  DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex.
What are the official names of this protein?
Transcription elongation factor SPT5, DRB sensitivity-inducing factor large subunit, DSIF large subunit.
What is the protein family that this protein belongs to?
Belongs to the SPT5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHR_HALSA
Sequence: MQLFWHRRDLRTTDNRGLAAAAPGVTAVDGGHDQGPVAAVFCFDDEVLAHAAPPRVAFMLDALAALRERYRDLGSDLIVRHGDPAAVLPAVANDLDATRVVWNHDYSGLATDRDAGVRDALDAAGVAHAQFHDAVHHRPGEIRTNAGDPYSVYTYFWRKWQDREKNPPAPEPEPADLAADTALADTSPLPSVQELGFAEPEAAVPDAGTAAARSLLDAFRESGDIYRYEDRRDYPHEEPTSRLSPHLKFGTIGIRTVYEAARAAKSDADTDDERENVAAFIGQLAWREFYAQVLYFNQNVVSENFKAYEHPIEWRDDPAALQAWKDGETGYPIVDAGMRQLRAEAYMHNRVRMIVAAFLTKDLLVDWRAGYDWFREKLADHDTANDNGGWQWAASTGTDAQPYFRVFNPMTQGERYDPDADYITEFVPELRDVPADAIHSWHELSLSERRRHAPEYPDPIVDHSQRREDAIAMFERARGDE
What is the function of this protein?
Involved in repair of UV radiation-induced DNA damage.  Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
What are the official names of this protein?
Deoxyribodipyrimidine photo-lyase, DNA photolyase, Photoreactivating enzyme.
What is the protein family that this protein belongs to?
Belongs to the DNA photolyase class-1 family.
Protein: GD_HHV1K
Sequence: MGGAAARLGAVILFVVIVGLHGVRGKYALADASLKMADPNRFRGKDLPVLDQLTDPPGVRRVYHIQAGLPDPFQPPSLPITVYYAVLERACRSVLLNAPSEAPQIVRGASEDVRKQPYNLTIAWFRMGGNCAIPITVMEYTECSYNKSLGACPIRTQPRWNYYDSFSAVSEDNLGFLMHAPAFETAGTYLRLVKINDWTEITQFILEHRAKGSCKYALPLRIPPSACLSPQAYQQGVTVDSIGMLPRFIPENQRTVAVYSLKIAGWHGPKAPYTSTLLPPELSETPNATQPELAPEDPEDSALLEDPVGTVAPQIPPNWHIPSIQDAATPYHPPATPNNMGLIAGAVGGSLLAALVICGIVYWMHRRTRKAPKRIRLPHIREDDQPSSHQPLFY
What is the function of this protein?
Envelope glycoprotein that binds to the potential host cell entry receptors TNFRSF14/HVEM, NECTIN1 and 3-O-sulfated heparan sulfate.  May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL (By similarity).
What are the official names of this protein?
Envelope glycoprotein D, gD.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein D family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs.
Protein: C144L_HUMAN
Sequence: MASWGGEKRGGAGGSPKPAVYATRKTPSVGSQEDQWYLDYPGDQWSLGFSYSWWKNSVGSESKHGEGALDQLQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLVPEYKEKQTPESLPQNNNPAAPSQAEGGEGGVACGTVEQMTWLCSLPHAVGGGDGDHSSTGAVGGHPRGPGEYCHLHEQRVHHHIFARGKRKGKNHVSNVVR
What are the official names of this protein?
Putative coiled-coil domain-containing protein 144 N-terminal-like.
What is the protein family that this protein belongs to?
Belongs to the CCDC144 family.
Protein: RS21_STAA1
Sequence: MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RL7_PSEAE
Sequence: MALTNEDIINAVSEMSVMQVVELIKAMEEKFGVTAAAATVAAAGPAAAAAEEQTEFTIVLAEAGDKKVNVIKVVRELTGLGLKEAKAVVDGAPGVVKEGASKEEAEAAKKALEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ATP8_USTMA
Sequence: MPQLLPFYFVNQISFAFLGLFVLLFVFSKYILPAFVELFVSRMYITKL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: TAGL_HUMAN
Sequence: MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS
What is the function of this protein?
Actin cross-linking/gelling protein (By similarity).  Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.
What are the official names of this protein?
Transgelin, 22 kDa actin-binding protein, Protein WS3-10, Smooth muscle protein 22-alpha, SM22-alpha.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_ENT38
Sequence: MATYYSNDFRAGLKIMMDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFYHFMNNTTFEQLSADEKAVGENAKWLLDQAECIVTLWNGQPISVTPPNFVELEIIETDPGLKGDTAGTGGKPAKLSTGAVVKVPLFVQTGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_THEPX
Sequence: MPKQKIRIRLKAFDHAILDQSAQKIVETAKRTGAEVSGPIPLPTEKDIITILRAPHKYKDSREQFEIRTHKRLIDILNPTPKTVDALMRLDLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: TMP_BPT4
Sequence: MKKPQEMQTMRRKVISDNKPTQEAAKSASNTLSGLNDISTKLDDAQAASELIAQTVEEKSNEIIGAIDNVESAVSDTSAGSELIAETVEIGNNINKEIGESLGSKLDKLTSLLEQKIQTAGIQQTGTSLATVESAIPVKVVEDDTAESVGPLLPAPEAVNNDPDADFFPTPQPVEPKQESPEEKQKKEAFNLKLSQALDKLTKTVDFGFKKSISITDKISSMLFKYTVSAAIEAAKMTAMILAVVVGIDLLMIHFKYWSDKFSKAWDLFSTDFTKFSSETGTWGPLLQSIFDSIDKIKQLWEAGDWGGLTVAIVEGLGKVLFNLGELIQLGMAKLSAAILRVIPGMKDTADEVEGRALENFQNSTGASLNKEDQEKVANYQDKRMNGDLGPIAEGLDKISNWKTRASNWIRGVDNKEALTTDEERAAEEEKLKQLSPEERKNALMKANEARAAMIRFEKYADSADMSKDSTVKSVEAAYEDLKKRMDDPDLNNSPAVKKELAARFSKIDATYQELKKNQPNAKPETSAKSPEAKQVQVIEKNKAQQAPVQQASPSINNTNNVIKKNTVVHNMTPVTSTTAPGVFDATGVN
What is the function of this protein?
Serves as a base for tail tube protein polymerization and acts as a template for tail length determination.
What are the official names of this protein?
Tape measure protein, TMP, Gene product 29, gp29, Tail length regulator.
What are the subcellular locations of this protein?
Virion.
Protein: Y3915_BACC1
Sequence: MAMRFLNIGYGNIVSAHRIIAIVSPESAPIKRTVQEAREHNALLDATYGRKTRAVIVMDDGHVVLSPIQPETIAHRLNNKEDLSEEG
What are the official names of this protein?
Putative regulatory protein BCE_3915.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: MTAP_PYRAE
Sequence: MVKLTNPPKSPKELGFDEFPSIGIIGGSGLYDPGIFENAVEVQIHTPYGLPSDNVIVGRVAGRVVAFLPRHGRGHKYPPHKIPYRANIYSLYMLGVRSIVAVSAVGSLRPDYAPGDFVVPDQFVDMTKGREYTFYDGPRTCHIQIGLEPFTQEIRQILIETAKKYNRTHDGGCYVCIEGPRFSTKAESRIWREVFGCDIIGMTLVPEINLARELGMCYGLIALVTDYDIWVPHQPVTAEAVEKMMTEKLGIIKKVIAEAVPKLPAELPKCSETLKYACV
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: AGT1_RABIT
Sequence: MASRQLLVAPPEALRKPLCTPHRLLLGPGPSNLPPRVLAAGGLQMIGHMHEEMYQVMDEIKQGIQYAFQTRNALTLAVSGSGHCALETALFNLLEPGDAFLVGANGIWGQRAAEVGERIGARVHPMIKDPGSHYTLQEVEECLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGAPIYMDQQGIDVLYSGSQKALNAPPGTSLISFSDKAKSKIYARKTKPFSFYMDVQLLANIWGCDGKPRMYHHTTPVIGIFALRESLALLVEQGLEKSWQRHREVAQHLYRRLQELGLQLFVKDPALRLPTVTTVIVPASYRWRDIVSYVMHHFGIEITGGLGPSADKVLRIGLLGCNATRENVDRLATALREALQHCAQSQL
What is the function of this protein?
Peroxisomal aminotransferase that catalyzes the transamination of glyoxylate to glycine and contributes to the glyoxylate detoxification (By similarity).  Also catalyzes the transamination between L-serine and pyruvate and contributes to gluconeogenesis from the L-serine metabolism (PubMed:10347152).
What are the official names of this protein?
Alanine--glyoxylate aminotransferase, AGT, Serine--pyruvate aminotransferase, SPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: SAPK3_ORYSJ
Sequence: MEERYEALKELGAGNFGVARLVRDKRSKELVAVKYIERGKKIDENVQREIINHRSLRHPNIIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLEICHRDLKLENTLLDGSPTPRVKICDFGYSKSALLHSKPKSTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLVGSYPFEDPGDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFVADPSKRITIPEIKKHTWFLKNLPKEISEREKADYKDTDAAPPTQAVEEIMRIIQEAKVPGDMAAADPALLAELAELKSDDEEEAADEYDTY
What is the function of this protein?
May play a role in signal transduction of hyperosmotic response.
What are the official names of this protein?
Serine/threonine-protein kinase SAPK3, Osmotic stress/abscisic acid-activated protein kinase 3, Protein kinase REK, stress-activated protein kinase 3, OsSAPK3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PPK5_APTFU
Sequence: SGDTSSQAKGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, Aptfu-PK-5, AptFu-Capa-PK, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HFQ_AERS4
Sequence: MAKGQSLQDPFLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPARAVNHHQHVPGAAGEEQGEAEA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RPOB_STRM5
Sequence: MTSYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYREFLQENVDPAKRTDHGLHAALKSVFPIASYSGNAALEYVGYKLGEPVFDERECRQRGMSYGAPLRVTVRLVIYDRESSTKAIKYVKEQEVYLGEIPLMTENGTFIVNGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDALFTRIDRRRKLPVSILLRALGYSNEEMLAEFFEINTFHINPDEGVQLELVPERLRGETLGFDLADGDKVIVEAGKRITARHIKQLEASGIAALAVPDDYIVGRILSHDVVDASTGELLAQANDEITDEQLQAFRKAGVDAVGTLWVNDLDRGPYLSNTLRIDPTKTQLEALVEIYRMMRPGEPPTKDAAQNLFHNLFFTFERYDLSAVGRMKFNRRVGRKETTGEAVLYDRKYYGERNDEESKRLVAAHGDSSDILDVIKVLTEIRNGRGVVDDIDHLGNRRVRSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLINSLAVYARTNQYGFLETPYRKVVDGKVYDEVEFLSAIEENEYVIAQANALTNADSVLTEQFVPCRFQGESLLKPPAEVHFMDVSPMQTVSIAAALVPFLEHDDANRALMGANMQRQAVPTLRAQKPLVGTGIERAVARDSGVTVNARRGGEIVQIDAARIVVKVVEEEIVGATDAGVDIYNLVKYTRSNQNTCINQRPLVQVGDIIARGDVLADGPSTDIGELALGQNMLIAFMPWNGYNFEDSILLSERVVEEDRYTTIHIEELTCVARDTKLGPEEISADIPNVSEQALNRLDESGVVYIGAEVRAGDIMVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDVQVFTRDGIEKDKRARQIEESEIKRVKKDFDDQFRILEAAIYMRLRSQIVGKVVNGGAGLKKGDVISDAFLDGLKKADWFALRMKDEDASEAIERAQKQIQAHEKEFERRFADKRGKITAGDDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNVVPVEDMPYMASGETVDIVLNPLGVPSRMNIGQILEVHLGWAAKGLGRKIQAMMEAQAAVADLRKFLDDIYNHDDTNVANRVDLSQFSDEELLRLARNLTDGVPMATPVFDGATEAEIKRMLELADLPSSGQTQLYDGRTGEAFDRHTTVGYMHYLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGEHEMVAGMPESFNVLVKEIRSLAINMELEDN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: BAMC_PSEU9
Sequence: MQYWIPKALAVSVLVSLSGCSVFTSDAHNERNYRAHEPVKAPASLSQPAQDPVYKMDVGQYDNNPEATNYRPPAQVLTIAKGSWVEEADKQARIYFDKNDGIEDLDVFIWDSIQAVLADNNISATQLDKTQGTLVTDWYAIVKPEESWLWGNDESVDLERFKFTIEEKEHQRTASLTAELIDFKGDKPLTDLLKQQLEVRALNQVVSEFDYRYRQLEVDMRKRQGIISLELGFDNKGNAALVTEQAYDTVFDRFSGFLERLSFTIVEINQETGLITADYAKVESSVWDSIWGDEPTELPIDEGQYQILVSKTKQGGTSLTWMDDKGETLEPGTMNGLQQALEAALIKRGIKI
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamC.
What is the protein family that this protein belongs to?
Belongs to the BamC family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RUVC_SHEPA
Sequence: MAIILGVDPGSRITGYGVIKCVGRQQVYVGSGCIRTSSDELPLRLKQIFDGLSEIIRQYQPDEFAIERVFMAKNADSALKLGQARGAAIVAATAANLPVAEYSATQIKSAVVGTGRAQKTQVQHMIQQLLKLPSAPQADAADALGVAVCHYHTSQSLVALAGRANVRTYGRYK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RS17_STRP1
Sequence: MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKKYKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PFKA_BACP2
Sequence: MKRIGVLTSGGDSPGMNAAVRAVVRKAIYHNVEVYGIYNGYSGLINGKIEKLEIGSVGDIIHRGGTKLYTARCPEFKTVEGREKGIENLKKFGIEGLVVIGGDGSFMGAKKLTELGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHERTYVVEVMGRHAGDIALWSGLAGGAESILIPEADYDMDEIIARLRRGHERGKKHSIIIVAEGVGSGVEFGKRIEEETSLETRVSVLGHIQRGGSPSAFDRVLASRLGAYAVELLLEGKGGRCVGIQSNELVHHDILDILDKKHTVDQNMYRLSQELSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_MYCA9
Sequence: MAIVPIRIVGDPVLHTPTQPVPVGPDGSLPDDLPELIANMYETMDAANGVGLAANQIGVPLRLFVYDCAETRGGGTRHRGVVINPVLETSEIPETMPDPDDDEEGCLSVPGESFPTGRAGWARVTGLDADGKEVTLEGNDLFARMLQHETGHLDGFLYIDKLIGRNARAAKRAVKSNGWGVPGLSWTPGQVADPFGH
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: ACCA_STAAE
Sequence: MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDIEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URIC_DROVI
Sequence: MFATPLRQLSSLKRSGIAGQEQAQLYEITNKGYGKDAVKVMHINRKGPVHSIQELEVGTHLKLYSNKDYMLGNNSDVVATDSQKNTVYLLAKKHGIESPEKFALILAKHFLSTYAHVEEVHVHVEAYPWQRMTQDVSDNIGKGYCENNCNSRSNGNCQLHNHAFIFTPTAHDYCDVILTRQDPKQTVISGIKGLRVLKTTQSSFVNFVDDEFRTLADQYDRIFSTVVECSWEYSDTESVNFLHAWETVKDIVVRNFAGDPSVGIPSPSVQHTLYLSEKQVLDVLPQVSVVSMTMPNKHYFNFDTKPFQQLVPGENNEVFIPTDKPHGTIYAQLSRKSLKSHL
What is the function of this protein?
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
What are the official names of this protein?
Uricase, Urate oxidase.
What is the protein family that this protein belongs to?
Belongs to the uricase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RACE_DICDI
Sequence: MSEDQGSGATRVKLVVVGDGAVGKTCLLICYAQNDFPVDYVPTVFENYTATRKRGNEDIKVHLWDTAGQEEYDRLRPLSYPGADVVLLCFSTISQSSYEAIRDKWAPEVNHYIPDVPSILVGTKIDLREQQHPDPNSGKFEPITADMGISMQKQIKAKKYLEVSAKTRQGLEEVFSAAIEIVLESRGMDKKSQDGSSSASGVPSGDKPTKGKAGKKKSGCIIL
What is the function of this protein?
Specifically required for cytokinesis.
What are the official names of this protein?
Rho-related protein racE.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: IPYR_CHLTR
Sequence: MSKTPLSIAHPWHGPVLTRDDYESLCCYIEITPADSVKFELDKETGILKVDRPQKFSNFCPCLYGLLPKTYCGDLSGEYSGQQSNRENIKGDGDPLDICVLTEKNITQGNILLQARPIGGIRILDSEEADDKIIAVLEDDLVYGNIEDISECPGTVLDMIQHYFLTYKATPESLIQAKPAKIEIVGLYGKKEAQKVIRLAHEDYCNLFM
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_PROM2
Sequence: MAKKSMIAREVKRKKLVKKYAAKRKSLLDEFNAAKDPMERLEIHRKIQGLPRNSAPNRVRNRCWATGKPRGVYRDFGLCRNQLRQRAHNGELPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: DTPB_YERE8
Sequence: MERSTPTGLLQQPKPFFMIFFVELWERFGYYGVQGILAVFFVQQLGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTMVLGAVVLAAGYFATGLSLYQPNLIFFALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLLSLSLAPVIAERFGYTVTYYLCGIGLIFALLVYFCCRHMVRHIGSEPDTKPLNWRNLLLVLLGSAVMICVCAWLMNHVFIANLVLIALSLIVVFIFFREASKQDRLGRNKMFVAFILMIEAIVFYVLYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPFWVVVASPILASIYTRLGSQNRDLSMPAKFTLGMFLCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLGELMISALGLAMVAALVPQYLMGFILGMWFLTQAASFLIGGYVATFTATPEGMTDPLETLPIYTDVFGKIGMVTLVIALVMALLIPWLNRMINSSAAEDAVA
What is the function of this protein?
Proton-dependent permease that transports di- and tripeptides.
What are the official names of this protein?
Dipeptide and tripeptide permease B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.