PharMolix/UniProtQA huggingface dataset:
Protein: SYP_THEP1
Sequence: MRMKDLYAPTLKETPSDVETVSHEYLLRGGFIRKVAAGIYTYLPLGRRVLLKIENIVREEMNRIGAQEILMPILQPAELWKQSGRWDDYGPEMMKLKDRHERDFTLGPTHEEIVTDLVKNELRSYKQLPLTLYQIANKYRDEIRPRFGLLRAREFIMKDAYSFHASWESLDETYEEFKKAYSRIMERLGVRYMIIEAETGAIGGNASHEFVVPAKIGETNVLFCEKCGYQASDEKAEYRGEYTQEQEKEKTLEKVPTPGVKTIEEVSKFLGVSPSKIVKSLLYKGREGYVMVLIRGDLELNEAKLKAHLKDQSLRMATPEEILKDFGVPVGFIGPIGVDVKKVADHSVRGLKNFVVGGMEEDTHYVNANHPRDFKVDEWYDLRTMVEGDPCPVCGEPLKATKGIELGHIFKLGTKYSEAMKAYFMDENGEMKPFIMGCYGWGVSRTMAAVVEHFHDENGMIWPLSIAPYTVVVDILNMNDAEQKQVGEKIYQVLSEKGEEVVLDDREVSPGFKFKDADLIGFPIRINVGRSLKEGVVELKKRYSKELVKVNIKNGFGTLLETLEKMKREYDPKEAAR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_ECO27
Sequence: MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLHVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_SALDC
Sequence: MPWIQLKLNTTGANAEELSDALMEAGAVSITFQDTHNTPVFEPLPGETRLWGDTDVIGLFDAETDMKDVVAILEQHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDIPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEAMKADVVVANILAGPLRELAPLISVLPVEGGLLGLSGVLASQAESVCDAYAELFTLDPVVEKEEWCRITGRKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRLA_DICDI
Sequence: MSNKDQEIKEEAPVAIEDLSNPVVVDSYNAAGIIANNAIKHVISKCVVGALVVDICQYGDDFIEAEAAKTFTKRKNLEKGIAFPTCVSVNNCVGHFSPLKGNTRTLKQGDVVKIDLGCHIDGYIAVGAHTIIIGNTSAESMTGKVADAICAAHYALEAALRMIRPGKTSNEVTQVIEKISDMYGVTSVSGILSHELKRFIIDGEKVIFSKNEPSQKIQTYEFQENEVYCIDIVMSTGEGKAREEADRPTIYRRNLDSTYKLKSKASRDFKDQIVKRYSALPFPLRNFDEKVSKLGLVELVEHQVLAAYPVLFDRSGCEVVQFKTTVLVLPNGNHKLIGTEFPLPFVRSEFSVTDDAIKALIASPLKINKKAAKKASATTIDVKMQ
What are the official names of this protein?
Proliferation-associated protein A.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family.
Protein: CYB_CYNGU
Sequence: MTNTRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGLCLAIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFVVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFVLPFIIAALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGVLLLILALMILVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILTLFPLLHVSKQRSMMFRPLSQCMFWFLVADLLTLTWIGGQPVEYPFITIGQLASILYFTIILLMLPIVSLFENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RTCB_ANOGA
Sequence: MVVREYNEEMKYIERLSPNSFLIKKGFQSNMNVEGIFYANSRLEKLMFDELRNACRPGMTGGFLPGVKQIANVAALPGIVGRSVGLPDIHSGYGFAIGNMAAFDMSDPTSIVSPGGVGFDINCGVRLLRTNLFEKDVQPVKEQLAQSLFDHIPVGVGSKGIIPMNAHDLEEALEMGMDWSLREGYVWAEDKEHCEEYGRMLNADPSKVSLRAKKRGLPQLGTLGAGNHYAEIQVVEEIYDKYAASKMGIEELGQICVMIHSGSRGFGHQVATDALVEMEKAMKRDKIETNDRQLACARINSPEGQNYLKAMSAAANFAWVNRSSMTFLTRQAFAKQFNTTPDDLDMHVIYDVSHNVAKMEEHMVNGRPKQLLVHRKGSTRAFPPHHPLIPVDYQLTGQPVLVGGSMGTCSFVLTGTETGMVETFGSTCHGAGRSLSRAKSRRNLDYKDVLRDLEEKGISIRVASPKLVQEEAPDSYKDVRDVVQTCHDVGISNKAIKLRPIAVIKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: CP2DQ_RAT
Sequence: MGLLIGDDLWAVVIFTAIFLLLVDLVHRHKFWTAHYPPGPVPLPGLGNLLQVDFENMPYSLYKLRSRYGDVFSLQIAWKPVVVINGLKAVRELLVTYGEDTADRPLLPIYNHLGYGNKSKGVVLAPYGPEWREQRRFSVSTLRDFGVGKKSLEQWVTEEAGHLCDTFAKEAEHPFNPSILLSKAVSNVIASLVYARRFEYEDPFFNRMLKTLKESFGEDTGFMAEVLNAIPILLQIPGLPGKVFPKLNSFIALVDKMLIEHKKSWDPAQPPRDMTDAFLAEMQKAKGNPESSFNDENLRLVVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHEEIDEVIGQVRRPEMADQARMPFTNAVIHEVQRFADIVPTNIPHMTSRDIKFQGFLIPKGTTLIPNLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVLAGRPRPSTHGVYALPVTPQPYQLCAVAR
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2D26, CYPIID26, Cytochrome P450-CMF2, Cytochrome P450-DB2, Debrisoquine 4-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: RL17_MESH7
Sequence: MANPHQIYRHDAAWDRQVFRSLATSLILHGHIKTTLDRAKRLRSVVEKLITKAKKNDLAARRQILSFLYGQKTKAGIKVMPYLFNKVAPRYQERNGGYTRIVRIPSRLGDNSKMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RR8_BARVE
Sequence: MGKDTIADIITSIRNADMNRKGTVRIGSTNITESIVKILLREGFIENVRKHRENNQYFLILTLRHRRNKKESYKTILNLKRISRPGLRIYSNSQRIPRILGGIGIVILSTSQGIMTDREARLKRIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TFB3_YEAST
Sequence: MLMDEYEENKDMCPICKTDRYLSPDVKFLVNPECYHRICESCVDRIFSLGPAQCPYKGCDKILRKNKFKTQIFDDVEVEKEVDIRKRVFNVFNKTIDDFNGDLVEYNKYLEEVEDIIYKLDHGIDVAKTEEKLRTYEELNKQLIMNNLERSRTEIESFEQRQKFEKEMKLKKRLLERQIEEEERMNKEWTKKEIVNRLSTTTQDINETIEGVKNTVKLKKSSARRKLEELNRVLKNNPYFNSNVNVQNSRLKDAVPFTPFNGDREAHPRFTLKGSVYNDPFIKDLEHRKEFIASGFNTNYAYERVLTEAFMGLGCVISEEL
What is the function of this protein?
Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA.  TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro.
What are the official names of this protein?
RNA polymerase II transcription factor B subunit 3, RNA polymerase II transcription factor B 38 kDa subunit, RNA polymerase II transcription factor B p38 subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADA1_NEIMB
Sequence: MKHFPSKVLTTAILATFCSGALAATSDDDVKKAATVAIVAAYNNGQEINGFKAGETIYDIGEDGTITQKDATAADVEADDFKGLGLKKVVTNLTKTVNENKQNVDAKVKAAESEIEKLTTKLADTDAALADTDAALDETTNALNKLGENITTFAEETKTNIVKIDEKLEAVADTVDKHAEAFNDIADSLDETNTKADEAVKTANEAKQTAEETKQNVDAKVKAAETAAGKAEAAAGTANTAADKAEAVAAKVTDIKADIATNKADIAKNSARIDSLDKNVANLRKETRQGLAEQAALSGLFQPYNVGRFNVTAAVGGYKSESAVAIGTGFRFTENFAAKAGVAVGTSSGSSAAYHVGVNYEW
What is the function of this protein?
Adheres to and induces bacterial uptake by human epithelial cells (Probable).  Upon expression in engineered Y. enterocolitica confers an 11- to 15-fold increase in bacterial adherence and uptake by human epithelial cell lines; part of the uptake is mediated by integrin beta-1 (ITGB1) suggesting it may be a human receptor for NadA (PubMed:21471204).  A bacterial cell surface protein; antisera against this protein induce complement-mediated killing of this and other strains (PubMed:12045242).
What are the official names of this protein?
Neisseria adhesin A, NadA variant 1.
What is the protein family that this protein belongs to?
Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
What are the subcellular locations of this protein?
Cell surface. Cell outer membrane. Note=Cell outer membrane localization shown in Y.enterocolitica.
Protein: SURE_SYNFM
Sequence: MRILLTNDDGVYAKGIETLYLALIEEHDVTVVAPETEQSAVGHAITWLDPLRVKPVHRNGHFFGHALTGTPADCVKIAVAELMSPPPDMVVSGVNMGANVGVNVIYSGTVSAATEAAVMGIPSMAVSIDSFQPTDFSAVTEFVPRLLRIVAKEGLPPGVCLNVNVPNLPADRIRGVKVTRQGHMKMVERYDRRIDPRGHVYYWLTNSALLRDDDPATDSLALARDYISVTPIHHDLTHYEMIDTLGKWNL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_PINTH
Sequence: MTLNLRVLSPNRVIWDSEVKEIILSTNSGQIGVLPNHASLVAAVDIGVMKIRLNGQWSTMAMMGGFAKIDSDRITILVNNAERDVDIDPREAQENFRIAKADLARAEGKRQAIEADLALKRARTRLEAINASPPVSN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RF1_CHLT2
Sequence: MEIKVLECLKRLEEVEKQISDPNIFSNPKEYSSLSKEHARLSEIKNAHESLVATKKILQDDKLALSTEKDPEIVAMLEEGVLVGEEAVERLSKQLENLLIPPDPDDDLSVIMELRAGTGGDEAALFVGDCVRMYHLYAASKGWQCEVLSASESDLGGYKEYVMGISGASVKRFLQYEAGTHRVQRVPETETQGRVHTSAVTVAVLPEPAEDDEEVFIDEKDLRIDTFRSSGAGGQHVNVTDSAVRITHIPSGVVVTCQDERSQHKNKAKAMRVLKARIRDAEVQKRAQEASAMRSAQVGSGDRSERIRTYNFPQNRVTDHRIGLTLYNLDRVMEGELDMITTALVTHVHRQLFGHEETA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSA_ENTHR
Sequence: MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINRGIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANLLEVENCQGMIAVNGDSKEITDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFTGPKTIVHNIRKCVENAGLVVNELVITPLALTETILSDGEKDFGTIVIDMGGGQTTTAVMHDKQLKFTSLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSANEEFPVDVIGQSEPVKVDERYLSEVISARMEQIFNKAKEALDQIEALELPGGIVLTGGAASLPGVVDLAQEIFGVNVKLYVPNQMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETVVAHHTTVEQEVTSYDNDSYDAPEETVYDEPEQKKSDEDVTTKIKGFFSKIFD
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring.
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Protein: YFBV_SHIB3
Sequence: MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMTRYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAILNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YfbV.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DSBB_BURTA
Sequence: MNNLTLSLHRERRLLVLLGLVCLALLAGALYLQYVKNEDPCPLCIIQRYFFVLIAVFAFIGAGMASGAGIAVIEALIVLSAAAGVGTAARHLYVQLNPGFSCGFDALQPVVDSLPPAHWLPGVFKVAGLCETVYPPIFGILLPGWALIAFALIVVPVAASLLRHRGRLR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WNT8A_MOUSE
Sequence: MGHLLMLWVAAGMCYPALGASAWSVNNFLITRPKAYLTYTASVALGAQIGIEECKFQFAWERWNCPEHAFQFSTHNRLRAATRETSFIHAIRSAAIMYAVTKNCSMGDLENCGCDESQNGKTGGHGWIWGGCSDNVEFGEKISRLFVDSLEKGKDARALVNLHNNRAGRLAVRASTKRTCKCHGISGSCSIQTCWLQLADFRQMGNYLKAKYDRALKIEMDKRQLRAGNRAEGRWALTEAFLPSTEAELIFLEGSPDYCNRNASLSIQGTEGRECLQNARSASRREQRSCGRLCTECGLQVEERRAEAVSSCDCNFQWCCTVKCGQCRRVVSRYYCTRPVGSARPRGRGKDSAW
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Plays a role in embryonic patterning.
What are the official names of this protein?
Protein Wnt-8a, Protein Wnt-8d, Stimulated by retinoic acid gene 11 protein.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: ACPS_YERP3
Sequence: MAILGLGTDIVEISRIEAVVERTGERLARRILSPSEWQHYQQHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVVNDALGKPTLRLHSRAAELAVELGVKSLHVTLADERRYACATVIIES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_METAC
Sequence: MEKKSLLILGTASHVGKSSVVTAICRILSRNYRVAPFKAQNMSLNSWITKDGKEIGIAQAIQAKAAGTEPTADMNPVLLKPKGDCVSQVILLGEPYADKSAGQYYDSIEEMNGVLEGALERLWKEHDIIVMEGAGGAAEINLYERDVVNVGTARLTQAPIILVGDIERGGVFASLYGTVALLPEDVKKNVKGFIINKFRGDPEILKPGLKQLEEITGIPVLGVLPHFKLRIPSEDSVSLGDKEGAKNEKEVEIAVIRLPRISNFTDFEPLEGLVKVHYVDIDEDLGNPDAIMIPGTKNTINDLLDLRASGMDKKIQAFKGKIPIFGICGGYQMLGRTIFDSGVENGVEAEFEGLRLLDIGTKFGEYKKRTIQVTKKVNGYGPILKSIDGEDIKGYEIHMGVTDSNRTVFGDDGAIDEEGLVIGTYLHGLFDNENIRNALVRYLCEKKGLEYRPEEIISENDAYEELANRFEQNIDMEKLYEIAGI
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Probable cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: COQ7_XYLFA
Sequence: MDVILSTRHHSHLDSLLIETQRVLEVVFGHPVAQRPSPANAFPNPLLSPKDRRHAAGLMRINHVGEICAQGLYFGQVAVARKEELRRHLLKAAQEETDHLSWCSDRLHELESRPSLFNPLWYSSSYMLGVFAGLLGDPWSLGFVVETERQVEAHLEKHLQVLPESDARSREILRVMKVEEARHADQADHAGARLLPSPIPGAMAWAARLMKVVAYRI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FOLD_RICM5
Sequence: MNNIIDGKALANEILADLKLEIQELISQTNASPKLAIVLVGDNPASIIYVRNKIKNAHKIGIYTLLVNLSTTIHTNDLISKINELNLDNKISGIIVQLPLPSSIDKNKILSAVSPSKDIDGFHPLNVGYLHSGISQNFIPCTALGCLAVIKKYEPNLTGKNVVIIGRSNIVGKPLSALLLKENCSVTICHSKTHNLSSITSKTDIVVAAIGSPLKLTAEYFNPESIVIDVGINRISGNKIIGDVDFENVQSKVKYITPVPGGIGPMTIAFLLKNTVKAFKDSLYTLDK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: YQGF_BACCN
Sequence: MRILGLDVGTKTVGVAISDEMGWTAQGLETIKINEEREIFGFDRVSELVKQYNVDKIVVGLPKNMNGTIGPRGEACQRYAESLRELLQLEVILWDERLSTMAAERLLISADVSRKKRKQVVDKMAAVVILQGYLDSK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYTS_STAA8
Sequence: MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
What is the function of this protein?
Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis, programmed cell death, biofilm formation and cell wall metabolism (PubMed:19502411).  Participates also in sensing and responding to host defense cationic antimicrobial peptides (CAMPs) (PubMed:23733465).  Functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to the conserved aspartic acid residue in the regulatory domain of LytR (PubMed:25491472).  In turn, LytR binds to the upstream promoter regions of target genes including lrgA and lrgB, to positively regulate their expression.  Possesses also a phosphatase activity that dephosphorylates and thus inactivates LytR (PubMed:25491472).
What are the official names of this protein?
Sensor histidine kinase/phosphatase LytS, Autolysin sensor kinase.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OR9A1_HUMAN
Sequence: MLGNYSSATEFFLLGFPGSQEVCRILFATFFLLYAVTVMGNVVIIITVCVDKCLQSPIYFFLGHLCVLEILITSTAVPFMLWGLLLPSTQIMSLTACAAQLYLYLSLGTLELALMGVMAVDRYVAVCNPLRYNIIMNSSTFIWVIIVSWVLGFLSEIWPVYATFQLTFCKSSVLDHFYCDRGQLLKVSCEDTLFREFILFLMAVFIIIGSLIPTIVSYTYIISTNLKIPSASGWRKSFSTCASHFTYVVIGYGSCLFLYVKPKQTQAAEYNRVVSLLVLVVTPFLNPFIFTLRNDKFIQAFGDGMKHCYKLLKN
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 9A1, HSHTPRX06.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTS_PROMM
Sequence: MADVSAKIVKDLRDKTGAGMMDCKKALAESDGDMVKASEWLRQKGIASAEKKSSRIAAEGAIGTYIHTGARVGVLLELNCETDFVARGDLFQGLLKDVAMQVAACPNVEYVSTEEIPVDVVEKEKSIEMGRDDLSGKPEQIKAKIVEGRIGKRLKELVLLEQPFIRDSSMTVAELVKQVAGKIGENIKVRRFTRYTLGEGIEVDQTDFATEVASMKTA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XRN2_CHAGB
Sequence: MGIPAAFRWLSTKYPKIISPVVEEKALVMEDGTVVPVDATQPNPNGEEFDNLYLDMNGIVHPCSHPEDRPAPSDEEEMMVEVFKYTERVVNMVRPRKLLMIAVADGVAPRAKMNQQRSRRFRAAQDAKEKEEDKQQLLKMLQKEKGSTAKEEPIETVVKKAFDSNSITPGTPFMDILAASLRYWCAYKLNTDPAWAKMKVIISDATVPGEGEHKIMEFVRSQRNSPEHDPNTRHVIYGLDADLIMLGLATHEPHFRVLREDVFFQQGKARMCKLCGQKGHDERNCRGEAKEKAGEFDEKDKAEPLKPFIWLHVSILREYLAIELNIPNLPFRWDLERAIDDWVFMCFFVGNDFLPHLPALEIRENGIETLMAIWKDNLPVMGGYVTKDGHVDLDRAQYILSGLAKQEDSIFRRRKETEDRREAGFKRRKLNNQQGNNRGGAHDSPLSGRGGRKGAPEANGPPVGMNLFPVASIPKPVITHDMVVNRANVANKSAASVLKSQIQSLVAQTQEKPEGDEPKEENPEAKTPPSALGKRKAELIEEGTATASDAASDTETPATTSSEEGPIDTVRLWEEGYADRYYEQKFKVDAKDIAFRHKVARAYVEGLAWVLMYYFQGCPSWEWFYPYHYAPFAADFVDLGKMKISFEKGRISRPFEQLMSVLPAASRHAIPEVFHDLMTQEDSPILDFYPEDFEIDLNGKKMSWQGIALLPFIEMPRLLDAMKTKSHLLSAEDKARNAPGHDVLLISDSHPGLYEDISSHFYSKKQAVPEFKLDPKRSDGLSGKVRKIEGYVPHGSLVYPLERNTMPDVDYDRSMSVNYDMPTSSHIHKSMLLRGLKMPTPALDRSDVDFVRSKGRGAGRSFGGVPLRNNYNGGGRGDRINYAGGPPRGGGGGGRGRGGYQQDRGYGNGYGGGGGSGGGGGGGGYGNGYGGYQQPAAPGQQSWQPPPPPGYPGFGVGVPPPPPPAHASGGGYNQGYGNQGYGGQNYRNDRYPPGPPPHGGYQGGGYPGGGYQGGGHQGGYQGQYHPPHGQSQDRRHDNS
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity.  Required for the processing of nuclear mRNA and rRNA precursors.  May promote termination of transcription by RNA polymerase II (By similarity).
What are the official names of this protein?
5'-3' exoribonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL1_PSEFS
Sequence: MAKLTKRQKAIAGKIEAGKAYNFVDAAALLTELSTVKFSESVDVAVNLGVDPRKSDQVVRSATVLPHGTGKTVRVAVFTQGPAAEAALAAGADRVGMDDLAAEMKGGDLNYDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVRYRTDKNGIIHTSVGKVGFDAVKLKENVEALIADLKRIKPASSKGIYVKRVTLSTTMGPGLVIDQGSLDV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.