PharMolix/UniProtQA huggingface dataset:
Protein: L_SHRV
Sequence: MEFFDLDLEVSQERLPAECSLNAPLNLSLSLQLFGRIEPKTENIRRQSRRITKVLRERHNGYRLQDLIIDSTRTQANLIPHLVSSASGDLNTPILEHWEMLSKYYQSLGYSLPSLDKFDFKESAGYWNAACSFRDMLLKSQKVEKKVNKQQTYVIYDITFEFVEGVVFIHGGEDGFNDGFLAGGAIAAMTYTELLALFKILNQRAQALLMCNISKGLEPDMVPSPSTIHSIYAEADHMLRMAGQGAIDLLKLWEPLVLTQLGDVLGDRFGLEDDFKLTIRTEAALLADQLNLKRSFARMTELIKSETRKQPLFQLFGLFKHFAYPRVYSRDTINTILGVSDKPSANDPEEYLHDQCEIRKEFYTRYVKAYHRAPQLDLGGLSPGSYLRRALEAGKMPNEKSPLYTNLEWFFVKFKKSIEWPLSDTLSTFLSDKAITQNRSTWLDNETSSRDNSEKRLLLKFIKENEDSVARVVAQAKEIYDNEDDRIIALKVKEMELKLKGRGFGLMTFKPRLLQVLRESIAKKTSKLFPEITMTASDLDLKKRKFLVSRKSDDRRGYVHMSKSLDINKFCTSQRQFNSQAVFQCLDELLGTGALFSRVHEIFEKTWIVDGSASDPPNLKKFKDRYQKLKDLGIDAPHTWGDGVFSGLMGGIEGLCQYVWTICLLLRVERVLSKTSLTHFVMAQGDNVIINLIIPIEIERDGSISPSEHRRVKSLSTSIDTQLAMELEKSGLTLKIEETLSSEHISIYGKDLHCPHHLTLSLKKAGSASIISSEQYQDVPTFLAGLSTSIETISECVNDKVSAHLFGVILAHAGWKSLCVSQTWKGWEYPYQKDETINRVRSQGIKLTEGEQVTVEKRLERNPDKRCLEWILATSFLGSALGMLPFPTPVDLEKRGVGDYITHRLALTKKALSSRVLPRRIEKLIRSMVNLPHSRETDLAKLFDSPFSLNLATEEDATSVIKRLARSTLRDLDIKNERLRAHIDIMDRGLQDLDRELGDSETINPRVAHLIRDITDEKESEMFVTKFATARTMRTVALENPQDVSVVSLLNKKSRAKETYTIWRSKRAPAEDWECSTQRAKIERDSSWGKNVIGVTSPSPVEAMSYRLVDPSTWEEEKKDQDFTINYYLSKPSLISHQARLERGPLVPYYGTQTQPLIAKAYNELKGNPKTNKALMLLSLRETIVKSGSNLDKLIMRLCERALDLDLNTLPSLRAQEEASSGEGIRGGIKESMSPVGPDNFYTNITHKVFNRRWLSGFHINIADFIIWGLTCTRKSITTQGTLSGNLPICIPACRGCLRRKEREFLDIDNPPRWECKEGVKDKAYMYFTTWCDLPRLSTLPSLDPQDAVFMIGRQLACSKGQDSGAATKFYNVSPESLGLLHPRMLLLGYSEGLIFSYLRSQHIVLGCLYHPTITELLPSLEKYTLETIDQHARQLGYLFQEEETAKELLNAGLCPYTPRAIPLTITELKNAVCITVSRSISVTLETKKSIHLMPESGISEEEVVAGRHAARTLGGLLNIKVPNLVYIDCDLTKGLLPWEPELPSEVLQSENFKIDGKRVTLYAKSQKRDNSIWEERGWTCSNSREILAKGVKTKSLFIHQSVPSHLDIDPALIVVIGGGLGGCVVPYLQHWRRPPVIFTTLFSERERISEDGDLIIPPELLVRGLSGRMVERELLEAELCDVTVPGNRKAIVDAVKRRIKPNESVLLIDEIENRGDAEDVLQQSISTLLQSLEKHCSLTSVHTIRESNVKHFTQRLNILRRGRYEANLFWNRYNRRDQYEALIVIPSESRMTECTFSVASVQAAFQKIDDGIEVEAKLEAHSWGLPELPPREKKILLGYVSSVFLKLGLVVIERHMSSTKLIDLLESAGPQMISWEEKQTHRSWASTDSIKEKGVTQDRIMALLCFAWTLKGLKHGVWDTNMDAVVEKTVYITHGPRLCALDEKPRVQYAEFKLQSKKRVEDLKGYLGALLHLETFFPLGDR
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the rhabdoviridae protein L family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=L and P are packaged asymmetrically towards the blunt end of the virus.
Protein: LIGB_ECO57
Sequence: MKVWMAILISILCWQSSVWAVCPAWSPARAQEEIFRLQQQIKQWDDDYWKEGKSEVEDGVYDQLSARLTQWQRCFVSEPRDVMMPPLNGAVMHPVAHTGVRKMADKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSLISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSLGVFVWAWPDGPQLMTDRLKELATAGFTLTQRYTRAVKNADEVARVRNEWWKAKLPFVTDGVVVRGAKEPESRHWLPGQAEWLVAWKYQPVAQVAKVKAIQFAVGKSGKISVVASLAPVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTPPENRFNSLTCYFASDVCQEQFISRLVWLGSKQVLGLDGIGEAGWRALHQTHRFEHIFSWLLLTPEQLQNTPGIAKSKSAQLWHRFNLARKQPFTRWVMAMGIPLTRAALNASDERSWSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: BRYP_PHYPA
Sequence: MAEAIIPAAELSIKTLQNIVEGITGVDRKIAIGFKNLTDYTLENLGVYFNSGSSDRSIAYKINAQEALLFSARKSDHTARGTVGTFSYYIQDEDKTVHVMWSVPFDYNLYSNWWNIAVVDGRQPPDSNVHDNLYNGSGGMPYPNKPDQYINNEQKGFHLFGSMTNNGQATIEVELKKA
What is the function of this protein?
Actinoporin-related protein having hemolytic activity in vitro.  Binds probably a phosphocholine derivative with the unique amido or hydroxyl groups found in sphingomyelin.  Involved in drought tolerance.
What are the official names of this protein?
Bryoporin, PpBP, Physcomitrin.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Plant subfamily.
Protein: EIF3B_CANGA
Sequence: MAAAEIKLEDIPVDDIDFTDLEKEYSVDDEFKFDNYVVVTGAPVIPESKVPVLKKALGGLFSKAGKVVDMEFPLDDDKKSKGFLFVECGSDVDAKKIIKAFHGKRLDLKHRLFLYSMRDVEKLSEQGAGEFVEPELPGFVPTSTLKSWLADEDGRDQFVIQKDNLTGIFWNSMHESEDDVVESRTNWSTNYVRFSPRGTYLFSYHPQGVTSWGGPQFDRLRRFYHPNVRTSSVSPDEHYLVTFSPEPIELDDSVPESPFTKRNEGHHICVWEIDTGLLCASFPLTKNPNLQWPFVKFSYNDKYCARFVGDRLAVYDCTNKFSLLEAPALKVSGIRDFSFAPTGVELQPFNKNDEPSVLLSYWTPETNNSACTASVVQVPRGRVLKTVNLVQVSNVTTYWPEGGEYLVFNVERHTKSKKTLFSNLQICKLTEKDIPVEKIEVKDRIMEVGWEPHGHRFITISTTEGPDDNIAIPKNVVRFYAPEKKEGVKNKIVVKRWVVIKEIEKKFYNTVSWSPAGRFVTVCALVKPNMRKSEFQFFDLDYPGEKNLNERKDVLATLKDVGESNYGAATDLCWDPSGRFLTAWSSSLKHKMENGYKMFNIAGVIIKEDILPNMKNFAWRPRPESLLSNAEKKKVRKTLKEWSAEFDEQDAMANDSAVRDLILKQRAMLKEWREYRAAKAQTTTIFDIAPWLDTTKDHEDFVKIEEIKEEIVEEIKEKL
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3 p90 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHH_OENPA
Sequence: MNVTTTRKDLMIVNMGPHHPSMHGVLRLILTLDGEDVIDCEPILGYLHRGMEKIAENRTVIQYLPYVTRWDYLATMFTEAITINGPEQLGNIQVPKRASYIRIIMLELSRIASHLLWLGPFMADIGAQTPFFYIFRERELVYDLFEAATGMRMMHNYFRIGGVAADLPYGWIDKCLDFCDYFLTAVSEYQKLITRNPIFLERVEGVGIIGGEEAINWGLSGPMLRASGIEWDLRKVDRYECYGELDWEIRWQKEGDSLARYLVRMSEMTESIKIIQQALEGIPGGPYENLEIRCFDIEKDPEWDGFEYRFISKKPSPTFELPKQELYVRVEAPKGELGIFLIGDQSGFPWRWKIRPPGFINLQILPQLVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: TLE1_MOUSE
Sequence: MFPQSRHPTPHQAAGQPFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQQQLQAQHLSHGHGPPVPLTPHPSGLQPPGIPPLGGSASLLALSSALSGQSHLAIKDDKKHHDAERHRDRESGTSNSLLVPDSLRSTDKRRNGPEFSSDIKKRKVDDKDNYDSDGDKSDDNLVVDVSNEDPSSPHASPTHSPRENGIDKNRLLKKDASGSPASTASSGSSSSLKSKEVSLHEKANTPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAMEPLVNQAAAGLRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYAGLHSMSPQMSAAAAAAAAAVVAYGRSPMVGFDPPPHMRVPSIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY
What is the function of this protein?
Transcriptional corepressor that binds to a number of transcription factors.  Inhibits NF-kappa-B-regulated gene expression.  Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling.  Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (PubMed:16314515).  The effects of full-length TLE family members may be modulated by association with dominant-negative AES.  Unusual function as coactivator for ESRRG (By similarity).
What are the official names of this protein?
Transducin-like enhancer protein 1, Groucho-related protein 1, Grg-1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat Groucho/TLE family.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear and chromatin-associated, depending on isoforms and phosphorylation status. Hyperphosphorylation decreases the affinity for nuclear components. SUBCELLULAR LOCATION: [Isoform 7]: Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Isoform 8]: Nucleus. Cytoplasm.
Protein: URE1_PROMS
Sequence: MSYKIDRKTYAQTYGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQVRRADGAVDTVITNALIVDWWGIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEVIAGEGHILTAGSIDTHIHFICPQQIETALSSGITTMLGGGTGPATGTNATTCTPGSFHISRMLQSAEAFPMNLGFFGKGNSTNEINLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADKFDVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSSTNPTRPYTRNTLEEHLDMLMVCHHLDSKIPEDIAFAESRIRRETIAAEDILHDLGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDRNDNYRVKRYISKVTINPAIAHGIDKHVGSIEKGKIADLVLWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFASFGQSLIKSSFTFLSKNSIEQNIPNKLGLQKKCIAVENTRNINKSNLKLNTKLPNISVDPQTYEVFSDGELLTCEPLDEVPMAQRYFLL
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP44_AILME
Sequence: MLTMDKCKHIGQLRLAQDHSILNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYVLNDNATGDLKLLRSMLSAIKSQNYQCTTRSGRVLRSMGTSDDTYYLHDGTQSLLQNEDQMYTALWHRRRILMSKIFRTWFEQSPTGRKRQEEQFQEKIAKREVKKRRQELEYQVKAELETIHPRKSLRLQGLAQSTTVEIVPVQVPLQTPASPAKDKVVSTSEDVRLKKASDSSGKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAVTASDKTRSPYKHPSITDTVYQMNECQETDTGSAPSRHPSLSLGLSGGASKSRKMELIQPREPSSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQHELETTGTRLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCNGKDIASQPCRVTEMLAKFTETEALEGKIYVCDHCNSKRRRFSSKSVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRESLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSKLLPPELLSGSQHPNEEADTSSNEILS
What is the function of this protein?
Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset.  Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C).  Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C.  Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint.  Promotes also the deubiquitination of histone H2A and H2B.  Recruited to RNF8/RNF168-ubiquitinated chromatin surrounding double stranded breaks (DSBs), promotes hydrolysis of such ubiquitin conjugates, thus negatively regulating protein recruitment to damaged chromatin (By similarity).  Participates in nucleotide excision repair (NER) pathway by deubiquitinating DDB2 to prevent its premature degradation so it can remain on damaged chromatin (By similarity).  Promotes FOXP3 stabilization through 'Lys-48'-linked deubiquitination leading to increased stability and increased regulatory T-cell lineage stability.  Plays also a positive role in innate immune response to DNA viruses by deubiquitinating STING1, selectively removing its 'Lys-48'-linked polyubiquitin chains and stabilizing it (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 44, Deubiquitinating enzyme 44, Ubiquitin thioesterase 44, Ubiquitin-specific-processing protease 44.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP44 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Peaks in interphase, with relatively low levels maintained throughout mitosis.
Protein: LPP_HUMAN
Sequence: MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLDDSSALPSISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL
What is the function of this protein?
May play a structural role at sites of cell adhesion in maintaining cell shape and motility.  In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription.  May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites.  Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.
What are the official names of this protein?
Lipoma-preferred partner, LIM domain-containing preferred translocation partner in lipoma.
What is the protein family that this protein belongs to?
Belongs to the zyxin/ajuba family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell junction. Cell membrane. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1.
Protein: RS8_DESAP
Sequence: MLTDPIADYLTRIRNANTAFHETTEVPASGIKKALTEILKEEGFIRGFEVVDDGKQGKIRIYLKYGKNKERVITGLKRISKPGLRVYAGKEEVPRVLGGLGIAILSTSKGIMTDKEARKEGIGGEVICYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SC11C_MOUSE
Sequence: MVRAGAVGTHLPTSSLDIFGDLRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11C, Microsomal signal peptidase 21 kDa subunit, SPase 21 kDa subunit, SEC11 homolog C, SEC11-like protein 3, SPC21.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: CAPP_PARMW
Sequence: MIMRSPETSGASMPQSTAHVPDGEQPRASGGSPGAGRLLQHRLELVEDLWQTVLRSECPPEQSERLLRLKQLSDPVALEGRDGESSSEAIVELIRSMDLSEAIAAARAFSLYFQLINILEQRIEEDSYLDSLRPSRSQDDETAAPFDPFAPPLASQTDPATFGEVFERLRRMNVPPAQVETLLRELDIRLVFTAHPTEIVRHTVRHKQRKVASLLQRLQSEPALPRYDEEELRRQLEEEIRLWWRTDELHQFKPTVLDEVDSTLHYFQQVLFEAMPQLRRRLVSSLSRHYPDVQFPQASFCTFGSWVGSDRDGNPSVTPEITWRTACYQRQLMLELYIGSVQSLRNQLSISMQWSQVAPPLLESLEMDRLRFPEIYERRAARYRLEPYRLKLSYILERLELTLQRNHQMSEAGWQSPPEPAATAPTDGIPGHEALHYTAIDQFRSDLELIRNSLVSTELSCEQLDTLLNQVHIFGFSLASLDIRQESTRHSDAIDELTTHLQLPKAYGAMEESERVAWLLEELQTRRPLIPAAVEWSEATAQTFAVFQMLHRLQQEFGQRICHSYVISMSHTASDLLEVMLLAKEIGLVDPQAGKASLLVVPLFETVEDLQRAPAVMDGLFQTPIYRNLLPSVGVQRQPLQELMLGYSDSNKDSGFLSSNWEIHQAQIALQTLASSHGVALRLFHGRGGSVSRGGGPAYQAILAQPSGTLQGRIKITEQGEVLASKYGLPELALYNLETVTTAVVQNSLVTNQLDATPSWNQLMSRVAKRSREHYRALVHDNPDLVAFFQQVTPIEEISKLQISSRPARRKTGARDLSSLRAIPWVFGWTQSRFLLPSWFGVGTALAEEVNDDPEQLDLLRRLHQRWPFFRMLISKVEMTLSKVDLDLAHHYMSSLGNPEQRDAFEGIFKVIADEYGRTLKLVLEITGQSRLLGADQNLQLSVDLRNRTIVPLGFLQVALLRRLRDQNRQPPMSESPGTPEDRRTYSRSELLRGALLTLNGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: PANB_LEPBL
Sequence: MKNIHKIFSPEKKGKEKISVVTCYDFSFARILGETPIDSILVGDSLGMVFQGNSSTLPVTLEEMIYHTKVVRRGAPDKFIIADLPFLSYQTSIEEGIRSAGRMMKETDCDAVKIEGGSDFICELVAILKQIGIPVMGHLGLTPQSVHVFGGHRVQGKGEESSAKLLREAVALSESGAFSIVLEMIPAELGKRVSEEVGVPTIGIGAGPDCDGQVLVLNDLLGLDANFQPKFLKKFSNLHSIVKDAIESYHEEVRSGEFPGKDHSF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_XANC5
Sequence: MNAVTKITPHTDYKIADISLADWGRKELDIAEHEMPGLMSIRRKHAQTKPLKDVRITGSLHMTIQTAVLIETLKDIGADVRWASCNIFSTQDHAAAAIAATGTPVFAWKGETLEEYWDCTLDALTFTLPDGTLTGPELVVDDGGDVTLLIHKGYELENGSTWVDEPASSHEEGVIKALLKRVAVERPGYWGRVVKDWKGVSEETTTGVHRLYQIAEAGKLLIPAINVNDSVTKSKFDNLYGCRESLADGLKRAMDVMLAGKVAVVCGYGDVGKGSAASLRAYGARVIVTEIDPICALQASMEGFEVNTIESTLGRADIYVTTTGNKDIITVEHLQAMKDQAIVCNIGHFDNEIQVDALKALKDVQKINIKPQVDKYVFPNGNAIFLLADGRLVNLGCATGHPSFVMSNSFANQTLAQIDLWEKRDTYEKKVYILPKHLDEEVARLHLEKIGVKLTTLTKDQADYLGVPVEGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_HELMI
Sequence: MRILLTNDDGIHAPGIHALWRIFDDWADIFVVAPDTERSATGHGITVHQPLRVEKLSFANPHCHGWAVNGTPADCVKLAMEELLAEPPHIVISGINRGPNLGTDVLYSGTVSAAMEGVIYGVPSIAVSVTGWHTADYTVAAETTRLLCEKLVARGLTPDTFLNVNVPDLPRERIAGIQVTKLGSRRYQNIFDKRTDPRGRTYYWMAGEVHDVDAGEGTDISAVNAGAISVTPIHFDLTNYSLIQEVSDWLGGGSSPFADRNKKDDVETKRKA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNUC_PSE14
Sequence: MTDALIRLEQVAVTLSGQSVLDNIQLSVKPGEIVTLIGPNGAGKTTLVRAVLGLLKPDSGTVWRKPKLRVGYMPQKLHVDQTLPLSVLRFLRLVPGVDRMAAESALEEVGAEKVIDSPIQGISGGEMQRVLLARALLRKPELLVLDEPVQGVDVAGQAELYGLITRLRDRHQCGVLMVSHDLHLVMSTTDQVVCLNRHVCCSGHPEHVSHDPAFVELFGKNAQSLAIYHHHHDHAHDLHGAVVNDAPATSSHTHTHVHGDHCKHG
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS15_PHEZH
Sequence: MSITAERKAELIKTHARGEADTGSAEVQVAILSERISNLTEHFKTHKKDNHSRRGLLKLVSQRRSLLDHLKKADQARYQDLIEKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SOPA_SALDU
Sequence: MKISSGAINFSTIPNQVKKLITSIREHTKNGLASKITSVKNTHTSLNEKFKTGKDSPIEFALPQKIKDFFQPKDKNTLNKTLITVKNIKDTNNAGKKNISAEDVSKMNAAFMRKHIANQTCDYNYRMTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLSLQATSSPSSPADWAKKLTDAVLRQKAGETLTAADRDFSNADFRNITFSKILPPSFMERDGDIIKGFNFSNSKFTYSDISHLHFDECRFTYSTLSDVVCSNTKFSNSDMNEVVLQYSITTQQQPSFIHTTLKNTLIRHKANLSGVILNEPHNSSPPSVSGGGNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTIDSLPDKYSQEKVQAMEDLVKSLRGGRLTEACIRPVESSLVSVLAHPPYTQSALIREWLGPVQERFFAHQCQTYNDVPLPTPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMTGVDCTDGTRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSSDWTTRAADNFLLLSSQDSDTAMMLSTDTLLTMLNPTPDTAWDNFYLQRAGENVSTAQISPVELFRHDFPVFLAAFNQQATQRRFGELIDIILSTEEHGELNQQFLAATNQKHSTVKLIDDASVSRLATIFDPLLPEGKLSPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALMQKAWELSPAIFPTSEQFTDWSDRFHGLHGAFTCTCVVADSMQRHARKYFPSVLSSILPLSWA
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway (By similarity).  Required for inducing polymorphonuclear leukocytes migration across the intestinal epithelium.
What are the official names of this protein?
E3 ubiquitin-protein ligase SopA, HECT-type E3 ubiquitin transferase SopA, Salmonella outer protein A, Secreted effector protein SopA.
What is the protein family that this protein belongs to?
Belongs to the SopA E3 ligase family.
What are the subcellular locations of this protein?
Secreted. Host mitochondrion. Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cell via a Sip-dependent pathway. Localizes to the mitochondria of host cell.
Protein: YCF48_SYNR3
Sequence: MIPVIRSFLSLLLCVGLTFGLGGCVTTSLPMAAASPWNSQKLGIESNPLDVAFTNESHGFLVGSNRLVMETSDGGETWEEREIDLPADENFRLISIDFNGDEGWIAGQPGLLLHSDDAGQSWSRLLLDTKLPGDPYLITALGSKKAELATNVGAIYQSSDAGKSWQAEVVDAAGSVRDLRRGDDGRYVSVSSLGNFFSTWDPGQSNWQVHQRVSSQRLQSMGYQPDGQMWMVTRGAQLRFNPEGGDYEEWSKPVIPITNGYGYLDMAWDPQGNIWAGGGNGTLLVSSDGGKEWEKDPVGTATPSNFTRFVFLGGNKAFALGERGAILRWVG
What is the function of this protein?
A factor required for optimal assembly of photosystem II (PSII), acting in the early stages of PSII assembly.  Also plays a role in replacement of photodamaged D1 (psbA).  Assists YidC in synthesis of chlorophyll-binding proteins.
What are the official names of this protein?
Photosystem II assembly lipoprotein Ycf48.
What is the protein family that this protein belongs to?
Belongs to the Ycf48 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Lipid-anchor; Lumenal side. Note=Associated with a PSII precusor complex on the lumenal side of the thylakoid membrane.