PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_SYNFM
Sequence: MITPLAKTAPAPRYLYVRTFGCQMNEYDSQRALRLLCAVGYRPTSDIADADVIFLNTCSVRDKAEQKVYSFLGRLRRLKAHRPWLKIVVAGCVAQQLGDGLLKRFEHVDLVVGTRGIGSIASLLEEVERSKRRVAHLPAEELQGFTTDKCRTVGTGDVVAQVTIMQGCNNFCTYCIVPHVRGRERSRAPDDILREIDFLASRGAREVLLLGQNVNSYGRGLPDPISFPDLLRRIGKETSIRRVRFTTSHPKDLTEDLIECFAGLPFLCKHLHLPFQSGSDGILKLMHRGYTARQYLEKIARLREVCPEIALSTDVIVGFPAESEEDYLQTLRLIEEVRFDSLFSFRYSDRPLTRAAGFPDKVPMDVKVRRLARLQSIQADITLQKNLAETGTVREVLVEGPSKASNGQMTGRTQQNRIINFQCPVDLTGKIVPVRIVAAYSHSLKGELLSQPGKES
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_PARL1
Sequence: MSRRHRAEKRDVIPDAKYGDVILAKFMNSLMYHGKKSAAETIIYGAFDQMQQKASVDPLRTFHEALENVMPALEVRSRRVGGATYQVPVEVRPDRRRALAIRWIIAAARARNETTMVARLSGELLDAANNRGSAVKKREDTHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PTXA_STUST
Sequence: MTPHPIQDAVLRVDRLSVVYPGGVTALRDTSIAFRRGEFTVLLGLSGAGKSTLLRSLNRLVTPTGGSVTSELGELGSGSALRQHRRRTAMIFQHHQLIERQSALANVLTGRLAFHNTLRSLFPLPRADQEIALSCLARVGLADKALSRVDKLSGGQQQRVGIARALAQQPAIILADEPVASLDPATSVRVLGLLRDICKEDGITAIVSLHQLEYARRFADRVVGLADSQIVFDAAPSELTDAQLERIYAGRSTTQPANAPAEPPVMLEPSLEMSR
What is the function of this protein?
Part of the ABC transporter complex PtxABC involved in phosphite import.  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Phosphite import ATP-binding protein PxtA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
Protein: VLP25_BORHE
Sequence: MRKRISAIINKLNISIMMMIVVLMIGCGQQAVEAGKDGAAAATGGRSLSEVLMEVGKSAENAFYSFMALVPDTLGLRVTKDTKKNEVGGYFNSLGGKLGKASDELEEVAKKSEVEGAKDGPIAVAIRAAVDTAKTTLSTLKEHLESLKGIGDDDKVGEATSNQNGVAASTDELKGAFKALKGIVDTAGKEGVAKPKAGDTAVKIGNADNKDGAKVLAAAANAGRAVGDKAAAIVSAVSGEEMLASIVASQEGDADAALAADATAQTSALKFARGGGNAGQLAKEAAKAAAVAGGIALRSLVKGGKLAANNNDDDKVVQSAGVTAVNKLLVAVEGIIKKTVKNVLEKAKGEIDKARAPKATGQ
What is the function of this protein?
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time.  Switching between these genes is a mechanism of host immune response evasion.
What are the official names of this protein?
Variable large protein 25, Variable major outer membrane lipoprotein 25.
What is the protein family that this protein belongs to?
Belongs to the variable large protein (Vlp) family. Alpha subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: GLBZ_CHITP
Sequence: MKFFAVLALCIVGAIAHPLTSDEAALVKSSWAQVKHNEVDILYTVFKAYPDIQARFPQFAGKDLDSIKTSGQFATHATRIVSFFSELIALSGSESNLSAIYGLISKMGTDHKNRGITQTQFNEFRTALVSYISSNVSWGDNVAAAWTHALDNVYTAVFQIVTA
What are the official names of this protein?
Globin CTT-Z, HBZ.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ARAA_MANSM
Sequence: MEFLKKLEVWFVVGSQDLYGDEALKQVNANAEQITRYLNDQNPFIQIKLKPLATTPEDILSLCQAANYEENCVGVIAWMHTFSPAKMWIGGLTRLNKPLLQFHTQLNKNIPWNEIDMDYMNLHQTAHGDREFGFMVSRFRKPRTIVVGHWQSESVKQKLDRWMRVLAAIYDQQHLKVARFGDNMREVAVTEGDKVEAQIKFGYSVNGYGLYQLVNSINTVNDEDITALVKEYEASYQLADSLKDGGEKRQSLIDSARIELGLKAFLDKGGFKAFTDTFQNLAGIKQLPGLPVQRLMAQGYGFGAEGDWKTAALVRAIKVMSYGLPNGCSFMEDYTYNLDDNNEIVLGAHMLEVCPSIANNKPILDIKPLGIGGKEDPARLIFTSKSGKATASTIVDLGNRFRMITADMQAVDKPQDMPNLPVGHAFWKLEPNFDIGTQAWILSGGAHHNVFSLDIDADMLRTFAEYFDIEFIHINVKTELPNLKNELRWNEAAYK
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: Y2891_VIBCH
Sequence: MARPKIPRRIECHPPASCFKPNGVPIRQLARVELAPDELEALRLVDQLGLQQQQAALQMQVSRQTLANLVKAARFKVVDCLLHQKALYIQAIDNKSSD
What are the official names of this protein?
UPF0251 protein VC_A0091.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: EMC9_HUMAN
Sequence: MGEVEISALAYVKMCLHAARYPHAAVNGLFLAPAPRSGECLCLTDCVPLFHSHLALSVMLEVALNQVDVWGAQAGLVVAGYYHANAAVNDQSPGPLALKIAGRIAEFFPDAVLIMLDNQKLVPQPRVPPVIVLENQGLRWVPKDKNLVMWRDWEESRQMVGALLEDRAHQHLVDFDCHLDDIRQDWTNQRLNTQITQWVGPTNGNGNA
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:30415835, PubMed:29809151, PubMed:29242231, PubMed:32459176).  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:30415835, PubMed:29809151, PubMed:29242231).  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:30415835, PubMed:29809151).  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes (PubMed:29809151, PubMed:29242231).  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (PubMed:30415835).  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).
What are the official names of this protein?
ER membrane protein complex subunit 9, Protein FAM158A.
What is the protein family that this protein belongs to?
Belongs to the EMC8/EMC9 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COX2_CHOFU
Sequence: MATWSNFNLQNSASPLMEQIIFFHDHTLVILIMITILVGYLMISLFFNSYINRFLLEGQMIELIWTILPAITLIFIALPSLRLLYLLDELNNPLITLKSIGHQWYWSYEYSDFQNIQFDSYMIPINEMKNNNFRLLDVDNRIVLPMNNQIRILVTATDVIHSWTIPSLGVKVDANPGRLNQTNFFINRPGIFYGQCSEICGANHSFMPIVIESISIKNFINWINNYS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: WFD13_MOUSE
Sequence: MRPVSPLQLLLVLSLAPQPVLGSPKQYFLKYILEPPPCRSEPGACNMFCTQQEECPEPLQCCSAYCGIVCTSNQAPVLGLS
What is the function of this protein?
Putative acid-stable proteinase inhibitor.
What are the official names of this protein?
WAP four-disulfide core domain protein 13, WAP four-disulfide core domain 13-like 1.
What are the subcellular locations of this protein?
Secreted.
Protein: MAS_MOUSE
Sequence: MDQSNMTSLAEEKAMNTSSRNASLGSSHPPIPIVHWVIMSISPLGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHHYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKHQSAFVCALLWALSCLVTTMEYVMCIDSGEESHSRSDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRVLYLLYYEYWSAFGNLHNISLLFSTINSSANPFIYFFVGSSKKKRFRESLKVVLTRAFKDEMQPRRQEGNGNTVSIETVV
What is the function of this protein?
Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels.  Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade.  The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1 (By similarity).  Receptor for angiotensin 1-7.
What are the official names of this protein?
Proto-oncogene Mas.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS14_BURM9
Sequence: MAKLALIEREKKRARLAQKYAPKRAELKAIIDDASKSDEERYAARLELQQLPRNANPTRKRNRCAITGRPRGTFRKFGLARNKIREIAFRGEIPGLTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: ADPRM_MIMIV
Sequence: MNNMIELRARNAILGAMVGDSLGSTFEFTKQKQAANKLAQYNYLSDGLIGKGPFGLKPGQFTDDTEIALAIMSVIHEYGYYDQYRVAEKYHEWYNSNPFDIGNTTKNSLSQNSCSDMIKASRKYNFGSMSNGSLMRLFGLVPMFYDRVPSSRTTKFIMKAIQQDIILTHSNPEMGPIAIIYGLMLWHAIQGHNASNVYKYGKLLAEKYHSDLYLSIYLSVDSEYDFFDYNDTRYHLNQIDSSNFGFVGFSIWLMLRSLKKHSDYRNAIIEIVSHGGDTDTNACITGALFGALYYNTIPSVWIDSVLNCQATERYQNYPIANPKIWSQWLP
What are the official names of this protein?
Putative ADP-ribosyl glycohydrolase L543.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family.
Protein: QUEA_CAMC1
Sequence: MSDINDISSYDYFLPEMLIAKEPVLPKEEARLLVYLKKTKEIKHYKFKDLASLIPDDAAVIFNNTKVIKARILGHKQSGGACEVMLNQPLGDNKFSVYVRGRVSVGSVLNFADDIKVNVLELNDDGSRVVNFTKNGVILDTAQLFSELEKIGHVPLPPYIKRADTKDDESWYQSIFAKNSGAVAAPTASLHFSEQMLERIKAKHDIAYITLHVGAGTFKGVECQNINDHKMHSEFYELSEKAQEIISSNKPILGVGTTVTRCVEEFARSKQSSGFCKLFLNLNNKPIRQNYLLTNFHLPKSTLIMLVTSFIGLEETMRIYETAVSEKYRFYSYGDGMLVI
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2759_HALH5
Sequence: MYCRMEFNFFMNDVVQMARKEMVESGYDQLTTPEEVDEVLKEKGTVLVMVNSVCGCAGGIARPAAAYMKNYDKKPDRFVTVFAGQDKEATARAREYFKGYAPSSPSFALLKDGEIQMMVERHEIEGHEPIQVVQKLEKAFDQYCS
What are the official names of this protein?
UPF0403 protein BH2759.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: CYCB_TAKRU
Sequence: MSGDIAKGKKAFVQKCAQCHTVEQGGKHKTGPNLWGLFGRKTGQAEGFSYTDANKSKGIIWSEETLMVYLENPKKYIPGTKMIFAGIKKKTERADLIAYLKSSTS
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
What are the official names of this protein?
Cytochrome c-b.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: CB046_HUMAN
Sequence: MVQREKARDNFEGGCLAELIGSPRDWKCFLAVPDPLLGVQHWLHLWRPQTKDGNSLHRHGDQAWGKHRRQNSLKSPALSGHSIDYHFYPRLRCGMLIGPDKQAVASGLEVLVTSSTKILGQLFPDAAHFLEEASEFKAE
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00299.
Protein: ILVD_METPP
Sequence: MSINRRSKNITEGVARAPNRSMYYAMGYQEADFKKPMIGVANGHSTITPCNSGLQKLADAAVEGIEAAGGNAQIFGTPTISDGMAMGTEGMKYSLVSREVIADCVETCVGGQWMDGVLVVGGCDKNMPGGMMGMLRANVPAIYVYGGTILPGKYKGQDLNIVSVFEAVGQFTAGNMSEEDFCQIERRAIPGSGSCGGMYTANTMSSAFEALGMSLPFASTMANVEDPIVAHTKEAARVLVEAVKADLKPRDIVTRKSIENAVAVIMATGGSTNAVLHFLAIAHAAGVEWTIDDFERVRRKVPVLCDLKPSGRYLAIDLHRAGGIPQVMKTLLAAGLIHGDCITITGRTVAENLADIPDAPRADQDVIRPITKPMYEQGHLAILKGNLSPEGAVAKITGLKNPSITGPARVFDDEQSALAAIMAKQIQAGDVMVLRYLGPMGGPGMPEMLAPTGALIGQGLGESVGLITDGRFSGGTWGMVVGHVAPEAAAGGTIALVQEGDSITIDAHTLVLNLNVSEAEIAKRRAAWKAPAPRYTRGVLAKFAKNASSASSGAVLDRFE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PORTL_BPLSK
Sequence: MNLFGKVVSFSRGKLNNDTQRVTAWQNEAVEYTSAFVTNIHNKIANEITKVEFNHVKYKKSDVGSDTLISMAGSDLDEVLNWSPKGERNSMDFWRKVIKKLLRAPYVDLYAVFDDNTGELLDLLFADDKKEYKPEELVRLTSPFYINEDTSILDNALASIQTKLEQGKLRGLLKINAFLDIDNTQEYREKALTTIKNMQEGSSYNGLTPVDNKTEIVELKKDYSVLNKDEIDLIKSELLTGYFMNENILLGTASQEQQIYFYNSTIIPLLIQLEKELTYKLISTNRRRVVKGNLYYERIIVDNQLFKFATLKELIDLYHENINGPIFTQNQLLVKMGEQPIEGGDVYIANLNAVAVKNLSDLQGSRKDVTSTDETNNQ
What is the function of this protein?
Forms the portal vertex of the capsid.  This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection.  The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.  Binds to the terminase subunits to form the packaging machine.  Necessary to ensure correct procapsid size during capsid assembly.  Once the capsid is packaged with the DNA, the terminase complex is substituted by the connector proteins gp15.
What are the official names of this protein?
Probable portal protein, Gene product 4, gp4, Putative portal protein.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus portal protein family.
What are the subcellular locations of this protein?
Virion. Note=Occupies the twelfth vertex of the capsid.
Protein: LYRM4_HUMAN
Sequence: MAASSRAQVLSLYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIGQLYSTDKLIIENRDMPRT
What is the function of this protein?
Stabilizing factor, of the core iron-sulfur cluster (ISC) assembly complex, that regulates, in association with NDUFAB1, the stability and the cysteine desulfurase activity of NFS1 and participates in the [2Fe-2S] clusters assembly on the scaffolding protein ISCU (PubMed:31664822, PubMed:17331979).  The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis.  This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner.  Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly.  Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5 (By similarity).  May also participates in the iron-sulfur protein biogenesis in the cytoplasm through its interaction with the cytoplasmic form of NFS1 (PubMed:19454487).
What are the official names of this protein?
LYR motif-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus.
Protein: RSMG_MYCS5
Sequence: MEFKNKVIAYCKERNANFLDFEKYVSLIEEHNKNINLTGFSGESLWEEGILNSLLYMNSSTKDKSEIKILDIGSGVGFPAIPYALLRENNSIDIFEPIQKRVDFLNLVKQKLTLDKVNIYKQRAEEFSQKNIYDVVVARAVGSVKTMLMAAFHLVALKGEMVLIKGPKYKQEILEAQEILSKLKVEVIVDKFILNAKENFLVRIKKLRNCPKEFPYSWKDIKKQS
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C2_OENAR
Sequence: MIWHVQNENLILDSTIIFMKAFHLPLFDGSFIFPEGILIFGLILLLMIDSTSDQTDIPWFYFISSISLVMSITALLFRWREEPRILFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHPLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDANGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLFTSVVSIYYYLKIIKLLMTGRKQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: G6PI_STAS1
Sequence: MTHIQLDYGKTLEFFGEHELQQQKDIVKSIHNTIHKGTGAGSDFLGWIDLPVDYDKEEFSRILEASKRVKDNSEVFVVIGIGGSYLGARAAIEMLTSSFRNSDEYPEIVFVGNHLSSTYTQELIDYLDGKDFSVNVISKSGTTTEPAVSFRLFKQLLENKYGKEEAKKRIFATTDKEKGALKQLATNEGYETFVVPDDIGGRYSVLTAVGLLPIAVAGIDIKAMMEGAAKAREELSSENLEDNIAYQYATIRNVLYAKGYDTEMLINYEPSMQYFNEWWKQLFGESEGKDYKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNNPKHDITIEEDSDNLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNIVLNIPRLDEETFGYVVYFFELACSMSGYQLGVNPFNQPGVEAYKQNMFALLGKQGFEDKKEALEKRL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDRG2_BOVIN
Sequence: MAELREVQITEEKPLLPGQTPEVAKTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFADMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCILQYLNFSTIIGIGVGAGAYVLSRYALTHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSISEMILGHLFSQEELSGNSELIQKYRNIIAHAPNLDNIELYWNSYNNRRDLNFVRGGDTTLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASIDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC
What is the function of this protein?
Contributes to the regulation of the Wnt signaling pathway.  Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor.  May be involved in dendritic cell and neuron differentiation (By similarity).
What are the official names of this protein?
Protein NDRG2, N-myc downstream-regulated gene 2 protein.
What is the protein family that this protein belongs to?
Belongs to the NDRG family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Note=In neurons, seems to concentrate at axonal growth cone. Perinuclear in neurons (By similarity).
Protein: SUCC_CUTAK
Sequence: MDLYEYQARDLFEKHGVPVLRGIVAETPEQASEAAAKLGTPVVAVKAQVKVGGRGKAGGVKIAKSAAEAAERAEAILGMDIKGHTVHKVMVAEGADIAEEYYFSILLDRGERRYLAMCSREGGMDIETLAKERPEALAKVPVDPIDGVDDAKAREILSEAGFPDSEQDAIVPAVLKLWETYRDEDATLVEVNPMIKTGDGRILAIDGKMTVDNNASFRQPDHAGLVDRATTDPLELRAGELGLNYVKLDGNVGVIGNGAGLVMSTLDCVAYAGENFPGSPAPANFLDIGGGASAEIMANGLDLIMSDEQVRSVFVNVFGGITACDQVALGIKGALEKLGDKAVKPLVVRLDGNAVAEGRKILEEFNYPLVTMVSTMDEAASKAAELASKEA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PHNN_RHOPA
Sequence: MTDIAVAEQTTKLIGPGRLVLVVGPSGAGKDTLINAARTLCADDPAIVFARRVVTREASAAEDNLQVTPDDFSRLEAAGDFALHWRAHGHAYGLPRGLDDDIRAGRTVVANVSRMVIDPARSAYANVVVVLITAPAEVLAARIAARARASDGSITDRVGRSVAAHPDVTISNVGDPIAHARDLLEIIRHGRPQP
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: RS3_DICT6
Sequence: MGQKTHPYGFRLGITKDWKSHWYAERSDYSSLLHEDWAIRNYLKKNYYQAGISLIEIERKAANRVDITIHTARPGMLIGRGGSEIENIRKNLIKLTNKNVFVNVQEVKNPELDAQLVAENIAMQIEKRINYKRAMKQAINRALRAGAKGIKVMCSGRLNGAEIARSEWFREGRIPLQTLTADIDYGFAEAFTISGVIGVKVWIYKGDVPELHKEAIQELPEKAVPKKIEDEDLYEKDEVNYDVDA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MDH_BURO1
Sequence: MAKPAKRVAVTGAAGQIAYSLLFRIANGDLLGKDQPVILQLLDLPQAQGAVKGVVMELDDCAFPLLAGVVITDDPKVAFKDADVALLVGARPRSKGMERKDLLSANAEIFTVQGAALNEVASRDVKVLVVGNPANTNAYIAMKSAPDLPKKNFTAMLRLDHNRALSQLAAKSGKPVASIEKLAVWGNHSPTMYPDFRFATAEGESLLKLINDDVWNRDTFIPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGTNGKWVTMGIPSDGSYGIPEDIIYGVPVTCENGEYKRVEGLEIDAFSREKMDGTLAELLEERDGVAHLLKN
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.