PharMolix/UniProtQA huggingface dataset:
Protein: ACPS_MYCSS
Sequence: MAIVGVGIDLVSIPDFAEQVDRPGTVFAETFTPGERRDAADKSSSAARHLAARWAAKEAVIKAWSGSRFAKRPALPEGIHRDIEVVTDMWGRPKVRLTGDIAEHLREATIHVSLTHEGDTAAAVAVIEEP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOHJ_ECOHS
Sequence: MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAVSTLVVFLVVSWSSQLVHGERKVVGQKGSEE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: REP_CDDV1
Sequence: MTDNDYPFDMLSQLSRLSQMSGIEDIIIETQPQESISDLNMIDSEAASVASVTNDRTLMRRCIVTLFFNDTAENLADWALDPASYFNEPEKDIKEWVGQFELCPTTNHLHAHIHVHFARQMRFQFIRDQFSAVSQIKLGDIKKGRGTSKHAVQCAVNYCIDPRKRHPEEPFNEAYLWPGNKTKWEFDQACADKQTKKKPTKEQLVKDKIALVDSFPYHWTWDQIVHSSDEAKELFFGCSASERYHKTRAVVQARRVIESVEIHYGAGGTGKSTFARQLGTKLGETSGRDEKYTRNYDDGNFWGGGITKYAGEAVVHLEEFEGQETLSKFKDICELGASGPNVNVKNGGTTLNHSHVVITSNTHPAGFYKGVWKGDPKQFAPFWRRITKLVFYPAHLPDGSLNAPKCDEDVYSIDQTEEWKALQGNYEGCLKMAERDWALRDDDLDSNKRPFDDAFSEGFVLPRPRQMQRSATEHNLFQYARSGRDPTS
What is the function of this protein?
Plays an essential for the replication of viral DNA.  Presumably cleaves viral genomic dsRNA replicative form to initiate rolling circle replication.
What are the official names of this protein?
Replication-associated protein, Rep.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PETG_PINKO
Sequence: MIEALPSGIVLGLIPITLAGLFVTAYSQYRRGDQLDI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: URE31_BRUME
Sequence: MNLTPREKDKLLIAMAAMVARRRLERGVKLNHPEAIALVSDFVVEGARDGRTVAELMEAGAHVITREQVMDGVAEMIRDIQVEATFPDGTKLVTVHEPIR
What are the official names of this protein?
Urease subunit gamma 1, Urea amidohydrolase subunit gamma 1.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2588_MYCBO
Sequence: MPGSAGWRKVFGGTGGATGALPRHGRGSIVYARSTTIEAQPLSVDIGIAHVRDVVMPALQEIDGCVGVSLLVDRQSGRCIATSAWETLEAMRASVERVAPIRDRAALMFAGSARVEEWDIALLHRDHPSHEGACVRATWLKVVPDQLGRSLEFYRTSVLPELESLDGFCSASLMVDHPACRRAVSCSTFDSMDAMARNRDRASELRSRRVRELGAEVLDVAEFELAIAHLRVPELV
What are the official names of this protein?
Uncharacterized protein Mb2588.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2557.
Protein: RL4_BRUA2
Sequence: MDLTITTLEGKDAGKVKLNEEIFGLDPRDDILQRVVRWQLARRQQGSHKAQGRGDVSRTGSKMYKQKGTGRARHHSARAPQFRGGGQAHGPVVRNHDHDLPKKVRALGLRHALSAKAKASDLIIIDDLASADAKTKQLVSQFAKLGLENALLIGGAEIDANFQRAASNIPNIDVLPVQGINVYDILRRGKLVLSKAAVEALEERFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: DPIB_ECOLI
Sequence: MLQLNENKQFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTASFEDYLTLHVRDMAMNQAKIIASNDSVISAVKTRDYKRLATIANKLQRDTDFDYVVIGDRHSIRLYHPNPEKIGYPMQFTKQGALEKGESYFITGKGSMGMAMRAKTPIFDDDGKVIGVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIARVVRQQEALFSSVYEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIVEVVRPADFFTEQIDEKRQDVVANFNGLSVIANREAIRSGDDLLGAIISFRSKDEISTLNAQLTQIKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGESQAQQQLIDSLREAFADRQVAGLLFGKVQRARELGLKMIIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLRSDEGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEHGIGLYLIASYVTRCGGVITLEDNDPCGTLFSIYIPKVKPNDSSINPIDR
What is the function of this protein?
Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance.  Could be involved in response to both the presence of citrate and external redox conditions.  Functions as a sensor kinase that phosphorylates DpiA in the presence of citrate.
What are the official names of this protein?
Sensor histidine kinase DpiB, Sensor histidine kinase CitA.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RM39_HUMAN
Sequence: MEALAMGSRALRLWLVAPGGGIKWRFIATSSASQLSPTELTEMRNDLFNKEKARQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVNKAYWRSCAMMMGCVIERAFKDEYMVNLVRAPEVPVISGAFCYDVVLDSKLDEWMPTKENLRSFTKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGPLIPRTSICFQYEVSAVHNLQPTQPSLIRRFQGVSLPVHLRAHFTIWDKLLERSRKMVTEDQSKATEECTST
What are the official names of this protein?
39S ribosomal protein L39, mitochondrial, L39mt, MRP-L39, 39S ribosomal protein L5, mitochondrial, L5mt, MRP-L5, Mitochondrial large ribosomal subunit protein mL39.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL39 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RIR1_DROME
Sequence: MLKNKSMKTSKLYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVINGLYCGVTTQELDNLAAEIAAGLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEFHYNVVKKNATRLNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIHGEDIDAAVETYNLLSERYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGTSICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRARDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLHDVWGDEFEKLYEKYEQEGRANRTVKAQSLWFAIIEAQVETGNPYMLFKDACNRKSNQQNVGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFVTPEKTYDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYESEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWDWQKLKESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHHLLRDLTELDLWDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGAFIDQSQSFNIHVAEPNYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVNKKQGAVSMNGQNGTAEGSPQKYEEDRERKMADMVCSLENKDACMSCGS
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: RIMK_ECO57
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: LIPB_FRAT1
Sequence: MNNIYQKDLGLQQYTKVFDDMLEFTSTRTPETNDEIWLVEHPAVFTQGKHGKPEHILNSHNIPIVATDRGGQVTYHGPGQAVIYFLLDIKRNKLGAKKLVTTVEQACINMLDKYYNLKAHIIDGAHGIYINNQKIASLGLRIKQGKSYHGIAINTNMDLTPFSYINPCGYSGLKMCQLANFYQEADIKKVQQQYTAEFVTLLNNSI
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_MYCVP
Sequence: MASVNIKPLEDKILVQANEAETTTASGLVIPDTAKEKPQEGTVVAVGPGRWDEDGEKRIPLDVSEGDVVIYSKYGGTEIKYNGEEYLILSARDVLAVVSK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAVN4_HUMAN
Sequence: MEHNGSASNADKIHQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAARPVYPPHEGREIPTPEPLKVTFKSQVKVEDDESLLLDLKHSS
What is the function of this protein?
Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation.  Facilitates the recruitment of MAPK1/3 to caveolae within cardiomyocytes and regulates alpha-1 adrenergic receptor-induced hypertrophic responses in cardiomyocytes through MAPK1/3 activation.  Contributes to proper membrane localization and stabilization of caveolin-3 (CAV3) in cardiomyocytes (By similarity).  Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway (PubMed:18332105).
What are the official names of this protein?
Caveolae-associated protein 4, Muscle-related coiled-coil protein, Muscle-restricted coiled-coil protein.
What is the protein family that this protein belongs to?
Belongs to the CAVIN family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere. Cytoplasm. Cytoplasm, cytosol. Cell membrane, sarcolemma. Membrane, caveola. Cell membrane. Note=In cardiomyocytes, accumulates in the Z-line of the sarcomere. In vascular smooth muscle cells, detected diffusely throughout the cytoplasm. Localizes in the caveolae in a caveolin-dependent manner.
Protein: SCL13_ARATH
Sequence: MQTSQKHHSAAGLHMLYPQVYCSPQFQAKDNKGFSDIPSKENFFTLESSTASGSLPSYDSPSVSITSGRSPFSPQGSQSCISDLHHSPDNVYGSPLSGVSSLAYDEAGVKSKIRELEVSLLSGDTKVEEFSGFSPAAGKSWNWDELLALTPQLDLKEVLVEAARAVADGDFATAYGFLDVLEQMVSVSGSPIQRLGTYMAEGLRARLEGSGSNIYKSLKCNEPTGRELMSYMSVLYEICPYWKFAYTTANVEILEAIAGETRVHIIDFQIAQGSQYMFLIQELAKRPGGPPLLRVTGVDDSQSTYARGGGLSLVGERLATLAQSCGVPFEFHDAIMSGCKVQREHLGLEPGFAVVVNFPYVLHHMPDESVSVENHRDRLLHLIKSLSPKLVTLVEQESNTNTSPFLSRFVETLDYYTAMFESIDAARPRDDKQRISAEQHCVARDIVNMIACEESERVERHEVLGKWRVRMMMAGFTGWPVSTSAAFAASEMLKAYDKNYKLGGHEGALYLFWKRRPMATCSVWKPNPN
What is the function of this protein?
Probable transcription factor that acts as a positive regulator of continuous red light signals downstream of phytochrome B (phyB).  Required for the regulation of hypocotyl elongation during de-etiolation.  May be required to modulate phytochrome A (phyA) signal transduction in a phyB-independent way.
What are the official names of this protein?
Scarecrow-like protein 13, AtSCL13, GRAS family protein 24, AtGRAS-24.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly cytoplasmic.
Protein: MB211_CHICK
Sequence: MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQSSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL
What is the function of this protein?
Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye (By similarity).  It is unclear whether it displays nucleotidyltransferase activity in vivo.  Binds single-stranded RNA (ssRNA) (By similarity).
What are the official names of this protein?
Putative nucleotidyltransferase MAB21L1, Protein mab-21-like 1.
What is the protein family that this protein belongs to?
Belongs to the mab-21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURP_ARCFU
Sequence: MGAMRDKILSVLEDYDKANIHIGTIGSHSALNILKGAKDEGFSTVCICREREKKVYESFGVADKFVIVSDYSDLLDENIQEELRHLNTILIPHGSFNAYIGKFDSLLLPMFGNRELMIWETDRDRQREWLERSGVRMPKKYSRPEEIEGLAIVKYPGAKGGKGYFIVSSPEEFYEISDEMVKKGLIGEEDIKNAEIQEYILGANIYFSFFYSPVYGRVELIAVDRRYESTADALGKVPAKEQIRANINPTYTVIGNFPVVLRESLLVQAFEAAEGIVEVSKEIAYPGMVGAFCIESIFDENALMYVFEISARIVAGTNVGIPTSPYSYILFGENMYMGRRIAREIKLAAEKDMLGELIY
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: HAZ1_ORYSJ
Sequence: MDKTTTSDLVLDNDNIGSNAGSAQEPLTTNGKTSGVRNRYKQTVKRGRKGSQISPSKTYPLRSSHSNVRVLRSASKKKNETPIVPTNDNTAVQRVAKKRKRSKPLRPAPSRVLRSTSEKKNKAHNELLNDGAGVQPAEKKRKVGRPPKGGTPKDDYLMIRKRVRYVLNRMNYEQSLIQAYASEGWKGQSLEKIRPEKELERAKVEILRCKSRIREAFRNLDSLLSEGKLDESMFDSAGEISSEDIFCAACGSKDVTLKNDIILCDGICDRGFHQYCLNPPLLAEDIPQGDEGWLCPACDCKIDCIDVLNELQGVKLSIHDSWEKVFPEAASFLNGSKQIDASDLPSDDSADNDYDPTLAQGHKVDEEKSSGEDGGEGLDSDDSSSEDSESSEKEKSKTSQNGRTVDDLGLPSEDSEDGDFDPAGPDSDKEQNDESNSDQSDESDFTSDSDDFCAEIAKSCGQDEISGPSSSQIRTVDRTDGSGFDGEPNAENSNLAFMETELEQDMVLPISSKRQVERLDYKKLYNEAYGKASSDSSDDEEWYGNSTPEKGNLEDSETDSLAESPQGGKGFSRRAPVRYHNNEHTPQNVRPGGSVSDQQTEVLCSNSNGSTAKNRHFGPAINQKLKAHFKEDPYPSRATKENLAQELGLTFNQVTKWFSSTRHYARVAATKKENNIENHTAENNNNTNTVDSIQLRGSNDIVSVDRNDMVSEERTGQSNLNEGTPLRSDTSCGQSVAVTPMVHPENQGNDSSSNVRTPNAKSAEKLIPGLENSDEARRKAVQRELRKMKTGR
What is the function of this protein?
Transcriptional repressor involved in the regulation of gibberrelin (GA) signaling.  Binds to the 5'-GATC-3' motif of HD16/EL1 promoter.  Functions as a positive regulator of GA signaling by suppressing the expression of HD16/EL1, a negative regulator of GA signaling.
What are the official names of this protein?
Homeobox protein HAZ1, Homeobox protein HOX1A homolog.
What is the protein family that this protein belongs to?
Belongs to the PHD-associated homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRP28_CANGA
Sequence: MLVLRKFRWRKWTAETLESTKMTRPIDVHQLLKSRSAGPKYMSVEERERVVIEHSNDEVDLGVEYAKKRNVDEVAEDSARESKKKSKRLDFDWDPADNTLEGYQPIVNPVILERIRQQEDQGDDLEAQYLGKSWREKLLVEMDERDWRIMREEFNITSKGKGAVKHPLRNWSETNVIPTDLVRALTEGMGFDEPTAIQRITIPNAISSNKSVPRDILGIASTGSGKTLAFSIPILARLDALPARPVNLKTLDGPLALVLVPTRELAQQISQEINRLLSAWENKKNLNAVSIVGGHSMSDISHTLRNGCDILIATPGRLLDVLDNHLVVLNKIQSLVLDEADRMIDLGFEDQMKSILSHLMADELAARQTMLFTATLSSSVESIAKGYLKNPLHVSVGSRWDSDKPLITQVVRHTGDDDKKLSFLKDDLIKNGLPAIIFINYKETADWLTLRLSDRFNIVTLHGSKSQSQRESAIQKLKSGTANVLIATNVAARGLDIPDVALVVNFQMSKKFDDYIHRIGRTGRAGKTGIAVTYLTGEEDPQLIKQLAKYVKDVDPNKENDFPEECAKHFGIVSETRNRIIY
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA splicing.  May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site.  May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL6_CLOTE
Sequence: MSRIGRLPIAIPNGVTVTVSPENVVTVKGPKGELTKTMHPNIDIAIEENSVIVTRKNDEKQNRSLHGLTRSLVNNMVVGVTEGYEKKLELVGVGYRAQLQGKKLVLNLGFSHPVEIEAKEGVEFQLDGTNKITVKGIDKELVGAVASDIRSWRKPEPYKGKGIKYENEAIRRKEGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YGHX_ECOLI
Sequence: MTALALFDLLKPNYALATQVEFTDPEIVAEYITYPSPNGHGEVRGYLVKPAKMSGKTPAVVVVHENRGLNPYIEDVARRVAKAGYIALAPDGLSSVGGYPGNDDKGRELQQQVDPTN
What are the official names of this protein?
Putative hydrolase fragment YghX.
Protein: US9_VZVD
Sequence: MAGQNTMEGEAVALLMEAVVTPRAQPNNTTITAIQPSRSAEKCYYSDSENETADEFLRRIGKYQHKIYHRKKFCYITLIIVFVFAMTGAAFALGYITSQFVG
What is the function of this protein?
Essential for the anterograde spread of the infection throughout the host nervous system.  Together with the gE/gI heterodimer, US9 is involved in the sorting and transport of viral structural components toward axon tips.
What are the official names of this protein?
Envelope protein US9, Envelope protein 65, ORF65 protein.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae envelope protein US9 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host Golgi apparatus membrane; Single- pass type II membrane protein. Host Golgi apparatus, host trans-Golgi network. Host cell membrane; Single-pass type II membrane protein. Note=During virion morphogenesis, this protein accumulates in the trans-Golgi where secondary envelopment occurs.
Protein: HEM3_FUSNN
Sequence: MKKNIIIGSRGSILALAQANLVKDRLQGNYPNLSFEIKEIVTSGDKDLKSNWENSDISLKSFFTKEIEQELLDGEIDIAVHSMKDMPAVSAKSLICGAIPDREDPRDVLVSKNGLLVTLPQGAKVGTSSLRRAMNLKTVRPDFEIKHLRGNIHTRLKKLETEDYDAIVLAAAGLKRTGLADKITEYLNGEVFPPAPAQGVLYIQCRENDEEIKEILKSIHNEAIAKIVEIEREFSKIFDGGCHTPMGCYSQVNGDKIKFTAVYLDEGKQIRAVVEDDLAKGKEIAYMAAEEIKNKIVK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ALG9_MOUSE
Sequence: MASRRARQRLKGGGGGGGGGGDAGPAAEKLEQLGSREAGAEPRPESGNKAGQVWAPEGSTAFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTPIAVLGVAAGAILGWPFSAALGLPIAFDLLARKHRWKSFLLWSLVALALFLVPVVVIDSYYYGKLVVAPLNIVLYNVFTSHGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICLCGAVALSALQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRTVPTHMNDQNREEPSRYIDISKCHYLVDLDTMRETPREPNYSSHREEWVSLAHRPFLDASRSSKLLRAFYVPFLSDQYTVYVNYTILKPRKAKPSRKKSGG
What is the function of this protein?
Catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides.
What are the official names of this protein?
Alpha-1,2-mannosyltransferase ALG9, Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ARCA_SALAR
Sequence: MMEKHFVGSEIGQLRSVMLHRPNLSLKRLTPSNCQELLFDDVLSVERAGEEHDIFANTLRQQGVEVLLLTDLLTQTLDVPDAKTWLLDTQISDYRLGPTFAADIRAWLADMSHRELARHLSGGLTYGEIPASIKNMVVDTHDINDFIMKPLPNHLFTRDTSCWIYNGVSINPMAKPARQRETNNLRAIYRWHPQFADGDFIKYFGDENINYDHATLEGGDVLVIGRGAVLIGMSERTTPQGIEFLAQALFKHRQAERVIAVELPKHRSCMHLDTVMTHIDIDAFSVYPEVVRPDVQCWTLTPDGHGGLKRTQENTLVHALEKALGIDQVRLITTGGDAFEAEREQWNDANNVLTLRPGVVVGYERNIWTNEKYDKAGITVLPIPGDELGRGRGGARCMSCPLERDGI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_ACHLI
Sequence: MKRTYQPSKIKHQRRHGFRARMATANGRKVLARRRAKGRQSLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CPFC_MYCTO
Sequence: MQFDAVLLLSFGGPEGPEQVRPFLENVTRGRGVPAERLDAVAEHYLHFGGVSPINGINRTLIAELEAQQELPVYFGNRNWEPYVEDAVTAMRDNGVRRAAVFATSAWSGYSSCTQYVEDIARARRAAGRDAPELVKLRPYFDHPLFVEMFADAITAAAATVRGDARLVFTAHSIPTAADRRCGPNLYSRQVAYATRLVAAAAGYCDFDLAWQSRSGPPQVPWLEPDVTDQLTGLAGAGINAVIVCPIGFVADHIEVVWDLDHELRLQAEAAGIAYARASTPNADPRFARLARGLIDELRYGRIPARVSGPDPVPGCLSSINGQPCRPPHCVASVSPARPSAGSP
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STABP_XENLA
Sequence: MPEHSDASLPPEERIRALVLKGTSVEVNDDIPPKRYYRSGVELIRMANVYSGEGSIENAFILYNKYITLFIEKLPKHRDYKTANVPEKKETLKKLKEIAFPKAEELKKELHKRYKKEYEEYSEKQRKEEEERARRLALQQQLDAEKQRVALLKQQQEQQEQVQAFEEMMRRKELEAERLRILHQFSKDEPEAEPLGSPLIPGMNEPPVTPLLPSYGTVQPHPPAVDRSLKPSSYGSNSSGVTSDGLRHVKIPRDVCCKFLQLSENNTQRGVETCGILCGKLLQNEFTVTHVIVPKQSGGPDYCNTESEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFKLTDYGMKEIGECRQKGFHPHCKEPPLFSAGGHVSVTEQDVTMMDLR
What is the function of this protein?
Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains.  Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity).  Functions at the endosome and is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes (By similarity).
What are the official names of this protein?
STAM-binding protein-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67C family.