PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_STRGG
Sequence: MTTTVETAAATGRVARVIGPVVDVEFPVDAMPEIYNALHVEVADPAEDGARKTLTLEVAQHLGDGVVRAISMQPTDGLVRQAPVTDTGTGITVPVGDVTKGKVFNTLGQILNEPEAEAQITERWPIHRKAPAFDQLESKTEMFETGLKVVDLLTPYVKGGKIGLFGGAGVGKTVLIQEMIMRVAKLHDGVSVFAGVGERTREGNDLIDEMTESGVLEKTALVFGQMDEPPGTRLRVALSALTMAEYFRDVQKQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGVLQERITSTRGHSITSMQAIYVPADDLTDPAPATTFAHLDATTVLSRPISEKGIYPAVDPLDSTSRILDPRYISQDHYAAASRVKGILQKYKDLQDIIAILGIDELGEEDKLVVHRARRVERFLSQNTHAAKQFTGLDGSDVPLDESIAAFNAICDGDYDHFPEQAFFMCGGLDDLKAKAKELGVS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TTCA_VARPS
Sequence: MNAVWIDEAPVAGAATNSLKIERETHKLEKRLCREVGRAIVDYNMIEEGDKVMVCVSGGKDSYAMLDILLKLRARAPIHFDIVAVNLDQKQPGFPEEVLPRYLSELGVDFHIENQDTYSIVKRVIPEGKTTCGLCSRLRRGILYRVADELGATKVALGHHRDDMLQTFFLNMFFAGKLKSMPPKLVSDDGKHIVIRPLAYVAEKDLVRWAQHREFPIIPCTLCGSQENLQRKQVGEMLREWDRKHLGRVENMFTALQNVVPSHLLDGTQHDFKGLKATGVADEDGDKAFDTPSFDLLSQAPAALRILQG
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCL11_ARATH
Sequence: MDALLQVSVDGFRFENGSGSCCKPRNNLESGNNLFPDFHESQNQSSPNDSPPTVCLDNSPVLKYINDMLMDEEDFVGISRDDLALQAAERSFYEIIQQQSPESDQNTSSSSDQNSGDQDFCFPSTTTDSSALVSSGESQRKYRHRNDEEDDLENNRRNKQPAIFVSEMEELAVKLEHVLLVCKTNQEEEEERTVITKQSTPNRAGRAKGSSNKSKTHKTNTVDLRSLLTQCAQAVASFDQRRATDKLKEIRAHSSSNGDGTQRLAFYFAEALEARITGNISPPVSNPFPSSTTSMVDILKAYKLFVHTCPIYVTDYFAANKSIYELAMKATKLHIVDFGVLYGFQWPCLLRALSKRPGGPPMLRVTGIELPQAGFRPSDRVEETGRRLKRFCDQFNVPFEFNFIAKKWETITLDELMINPGETTVVNCIHRLQYTPDETVSLDSPRDTVLKLFRDINPDLFVFAEINGMYNSPFFMTRFREALFHYSSLFDMFDTTIHAEDEYKNRSLLERELLVRDAMSVISCEGAERFARPETYKQWRVRILRAGFKPATISKQIMKEAKEIVRKRYHRDFVIDSDNNWMLQGWKGRVIYAFSCWKPAEKFTNNNLNI
What is the function of this protein?
Probable transcription factor involved in plant development.
What are the official names of this protein?
Scarecrow-like protein 11, AtSCL11, GRAS family protein 31, AtGRAS-31.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPG_HELPS
Sequence: MLENRVKTKQIFIGGVAIGGDAPISTQSMTFSKTADIESTKNQIDRLKLAGADLVRVAVSNEKDALALKELKRVSPLPLIADIHFHYKFALIAAQSVDAIRINPGNIGSKDKIKAVVDACKEKNIPIRIGVNAGSLEKQFDQKYGPTPKGMVESALYNAKLLEDLDFTDFKISLKASDVIRTIEAYRMLRPLVIYPFHLGVTEAGNLFSSSIKSAMALGGLLMEGIGDTMRVSITGELENEIKVARAILRHSGRLKEGINLISCPTCGRIEANLVDMASKVEKRLSHIKTPLDISVMGCVVNALGEAKHADMAIAFGNRSGLIIKEGKVIHKLAEKDLFETFVIEVENLAKEREKSLKD
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: SCPDL_BOVIN
Sequence: MATQQRPFHLVVFGASGFTGQFVTEEVAREQVSPERTSHLPWAVAGRSREKLLRVLERAAMKLGRPTLSSEVGIIICDITNPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGTSCIDISGEPQFLELMYWKYHEKAAEKGVYIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESFLTISSGPEGLCVHDGTWKSAVYGFGDKSNLKKLRNESDMKPVPIVGPKLKRRWPISYCRELNSYSIPFLGADVSVVKRTQRYLHENLEQSPVQYAAYINVGGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFTWLFSFGYFSKQGPTQKQIDASSFTMTFFGQGFSQGVSPVKNKPNIRICTQVKGPEAGYVSTSIAMVQAAMILLNDASDLPKAGGVFTPGAAFSRTKLIDRLNEHGIEFSVISSTEV
What are the official names of this protein?
Saccharopine dehydrogenase-like oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the saccharopine dehydrogenase family.
Protein: ITA9_HUMAN
Sequence: MGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPCYEEYKKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRRYTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNRKENEDSWDWVQKNQ
What is the function of this protein?
Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin.  It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin.
What are the official names of this protein?
Integrin alpha-9, Integrin alpha-RLC.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PPAD_YEAST
Sequence: MVKPVIFAICLGVLLSKALSIPLRSFADIELIGSQKSLFPFLGGSAPYFSFPANYGIPTDIPEGCRLTQVQMIGRHGERYPTRSEAKDIFEVWYKISNYTGKYEGSLSFLNNGYEFFIPDESLLEMETTLQNSIDVLNPYTGEMNAKRHAREFLAKYGKLMENCTNFPIFTTNSKRIYDTAQYFAEALGDGFNISLQTLSENSSSGANTLAAKSSCPNWNSNANNDILMSYSRDYLENISDRLNDENKGLNLSRKDAAALFSWCAFELNAKGYSNICDIFSAAELIHYSYETDLTSFYQNGPGYKLIKSIGANLFNATVKLIRQSAHLDQKVWLSFTHDTDILNYLTTAGLIDDTRNLTTNHVPFRDHSYHRSWYIPQGARVYTEKFQCSNDSYVRYVVNDAVVPIESCSSGPGFSCEEGTFYEYAKDRLRGVSFYEDCDVSKVSKEKELTFYWDWNTTRYNASLVNQ
What are the official names of this protein?
Probable acid phosphatase DIA3, Digs into agar protein 3.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
Protein: CH60_TREDE
Sequence: MAKQLLFNEEARKSLLAGVEQISNAVKVTLGPKGRNVLIDKSFGAPTVTKDGVSVAREVELENKFENMGAQLLKEVATKTNDVAGDGTTTATVLAYSMVKEGLKAVAAGMTPLELKRGIDKAVAIAVEDIQKNSKEIKGSEEVAHVASVSANNDAEIGKIIADAIAKVGKDGVIDVGEAQTMETVTDYVEGMQFDRGYISSYFVTDRDRMETVFENPYILIYDKSISTMKDLLPLLEQVAQSGRPLLIIAEDVEGEALATLVVNSLRGALKTCAVKAPGFGDRRKEMLEDIAVLTGGQVVSEELGFKLEAAQISMLGQAKSIKIDKDNTMIIDGAGKSKDIKDRVTQIKAQLDATDSEYDSEKLRERLAKLSGGVAVIKIGAVTEVEMKEKKHRVEDALSATRAAIEEGIVAGGGLAMIQAIAALEKADMSSLTEDEKVGFKIVKRALEEPIRQIAENAGLDGAVIAEKAKEKKGVGFDAAKMEWTDMVKAGIIDPAKVTRSALQNAASIASLLLTTECAITDIPEKQAGPAMPSPDMGGMGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_RICTY
Sequence: MSNTDKERAIAAALAQIEKSYGKGSVMKLGQRPNIDIEAISTGSLGLDIALGIGGVPKGRIIEIFGPESSGKTTLTLHLIAESQKNGGTCAFIDAEHALDPAYAKKLGVNIDELIISQPDTGEQALEIADTLIRSGGIDMIIIDSVAALVPKSEIEGEMGDAQMASQARLMSQALRKLTASINRTNCITVFINQIRMKIGVMFGSPETTTGGNALKFYASVRIDIRRIGSIKDKEEVIGSQTKVKVVKNKVSPPFKTADFDIMYGSGISKEGEIIDLGVKLEIIEKSGSWFAYNKVRIGQGRENVKQYLKEHPQIANEIEKIIREKSSAITNINLDQTEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_STRS2
Sequence: MLIFPLINDLSRKIIHVDMDAFFAAIEVRDSPALKGKPVIIGADPRLSGGRGVVSTCNYEARAFGIHSAMSSKEAYERCPQAIFISGNYEKYQEVGRQVREIFHRYTDLVEPMSIDEAYLDVTENKLGISSAVKIAKLIQYDIWNELHLTASAGVSYNKFLAKIASDMEKPHGLTLILPEDAVGILASLPVEKFHGVGKKTVERLHEMGVYTGQDLLDVPEMVLIDRFGRFGFDLYRKARGISNSPVKVDRVRKSSGKERTYRKLLYREEDVLKELISLCQRVAASLKRNGKKGRTIVLKVRYGDFSTLTKRHSLEVYTDQTETIEKEVRQLIEEIGKIEKGIRLLGVTVTNFQT
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_MAGSA
Sequence: MIQKNWQELIKPNKLHVEPGADPQRTAIVVAEPLERGFGMTLGNSLRRVLLSSLQGAAVTAIQIDGVLHEFSSIPGVREDVTDIILNIKTLGLRMHGEGPKRMHLRAVGPGEVTAGLIEVGHDIEIMDPELVLCTLDEGAKLNIEFTVETGKGYVPASQNRPEDSPIGLIPIDAIFSPVRKVAYKVENTRVGQVTDYDKLSMTVETNGAVTPDDAVALAARILQDQLQLFINFEEPTAVVEEEKKDELPFNKNLLRKVDELELSVRSANCLKNDNIIYIGDLVQKTEAEMLRTPNFGRKSLNEIKEVLAQMGLHLGMEIANWPPENIEELAKKLEEPY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: KAD_STRA3
Sequence: MNLLIMGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTEMGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLEELGLRLDGVINIKVDPSCLIERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDKPETVKRRLDVNIAQGEPILEHYRKLGLVTDIEGNQEITEVFADVEKALLELK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_DESOH
Sequence: MITPDFEKTGGLVPVVTQDAATGEVLMLAYINREAWETTLASGKATYYSRSRKQLWVKGESSGNVQIIKEIRIDCDNDTLLFRVEQIGGAACHRGYRSCFFTKVEADGTGRITQERVFDPAEVYKK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIKE1_XENTR
Sequence: MTCTIDKILQDAKTLLERLKDHDNAAESLIDQSSALHKRVEAMKEVGTAMPEKYQEELADIKDASKLKPHVLLCQENTQIRDLQQENKELWVSLEEHQYALELIMSKYRKQMLQLVANKKPAPTEPVLEAHKTFSSDLECQIDRICVMGDIMRDAIQLDEDKAYNIQEKLAQLELENKELREILSTSKESLHSSKRESEWNFSEKTQ
What is the function of this protein?
Suppressor of IKK-epsilon.
What are the official names of this protein?
Suppressor of IKBKE 1, Suppressor of IKK-epsilon.
What is the protein family that this protein belongs to?
Belongs to the SIKE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_WOLWR
Sequence: MRLSKYYLPTLKEKPAHAKIISHQYSLRAGLIKQIASGIYSWLPLGLLVLKNIEDIIRDEMDKSGAIEVLMPCVQPANLWRESGRYDDYGKEMLRIKDRHEEDMLFGPTHEEVATDLIRDVVKSYKDLPLCLYQIQWKFRDEVRPRYGVMRGREFLMKDAYSFDVDYEGALNSYNLMYKTYIKIFKRMGLTPIGVRADTGPIGGNLSHEFHILANTGESTLYYDNKFSELLESEDVESLKSIYAVADDMHDPETCPISQEQLNVSKGIEIGHIFYFGDKYSKPMKASVTSQDGKNVNIHMGSYGIGVSRLVGAIIEAFHDDKGIIWPESVAPFRIGLINLQTKVTEAADKIYKALKSDEVLYDDTEGSVGVKFSRMDLIGLPWQIIVGKKAIDEKIVEVKNRATGEVKEMQIEEAINHFSTK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M2_I07A0
Sequence: LTEVETPIRNEWGCRCNDSSDPLVVAASIIGIVHLILWIIDRLFSKSIYRIFKHGLKRGPSTEGVPESMREEYREEQQNAVDADDDHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: NHBA_NEIMH
Sequence: MKEMMMFKRSVIAMACIFALSACGGGGGGSPDVKSADTLSKPAAPVVSEKETEAKEDAPQAGSQGQGAPSAQGSQDMAAVSEENTGNGGAVTADNPKNEDEVAQNDMPQNAAGTDSSTPNHTPDPNMLAGNMENQATDAGESSQPANQPDMANAADGMQGDDPSAGGQNAGNTAAQGANQAGNNQAAGSSDPIPASNPAPANGGSNFGRVDLANGVLIDGPSQNITLTHCKGDSCSGNNFLDEEVQLKSEFEKLSDADKISNYKKDGKNDKFVGLVADSVQMKGINQYIIFYKPKPTSFARFRRSARSRRSLPAEMPLIPVNQADTLIVDGEAVSLTGHSGNIFAPEGNYRYLTYGAEKLPGGSYALRVQGEPAKGEMLAGAAVYNGEVLHFHTENGRPYPTRGRFAAKVDFGSKSVDGIIDSGDDLHMGTQKFKAAIDGNGFKGTWTENGSGDVSGKFYGPAGEEVAGKYSYRPTDAEKGGFGVFAGKKEQD
What is the function of this protein?
Plays a role in extracellular-DNA (eDNA) mediated biofilm formation.  In some strains (including cc32 strain H44/76 but not cc11 strain B16B6) eDNA stimulates biofilm formation.  When NHBA is not processed by NalP, biofilm formation increases (PubMed:23163582).  This is probably because the number of positively charged, NHBA- and IgA-derived DNA-binding peptides on the cell surface rises, resulting in increased DNA-binding peptides and increased biofilm formation (Probable).
What are the official names of this protein?
Neisserial heparin binding antigen, NHBA, Genome-derived Neisseria antigen 2132, GNA2132.
What is the protein family that this protein belongs to?
Belongs to the NHBA family.
Protein: LYSA_DICDI
Sequence: MRIAFFLLVLAVIIGFAYGYSCPKPCYGNMCCSTSPNNQYYLTDFCGSTSACGPVPSCSGALYFTADSQRFGCGKYLNLCRSGKCVKAQIYDAGPAMWVEQDAGMMIIDASPTICHVLTGGSSCGWSDHFLITATVTSLTDSRPLGPFNVTESEMAQLFIDHEIAMAQCEAEKTCNGFDLE
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacteria B. subtilis, B. megaterium and M. luteus.  No antibacterial activity detected against the Gram-positive bacterium S. aureus or against the Gram-negative bacterium E. coli.  Lacks chitinase activity.
What are the official names of this protein?
Lysozyme A, 1,4-beta-N-acetylmuramidase A.
What is the protein family that this protein belongs to?
Belongs to the dictyostelium lysozyme family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle lumen.
Protein: SYA_STAA3
Sequence: MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAISGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQLKVKSDDQVVDKLTQLQDEEKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPB4_SCHPO
Sequence: MNQDKSKETSELDDLALPRSIIMRLVKGVLPEKSLVQKEALKAMINSATLFVSFLTSASGEIATNNNRKILMPQDVLNALDEIEYPEFSKTLKKHLEAYELALKEKRLKLPNVSDVDNRKKAKIDAHDTTPLDEEKDELEEERIAEDIAQNEVEQNIDDVEDLEEVNDTLDANAESPQIETIHLTDATGNPIEDSSESDSEESLQLNDSS
What is the function of this protein?
As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.  It is required during synthesis of the leading and lagging DNA strands at the replication fork and binds at/or near replication origins and moves along DNA with the replication fork.  It has 3'-5' proofreading exonuclease activity that correct errors arising during DNA replication.  It is also involved in DNA synthesis during DNA repair (By similarity).  The dpb3-dpb4 dimer associates with histone deacetylases, chromatin remodelers, and histones and plays a crucial role in the inheritance of histone hypoacetylation and H3K9 methylation in heterochromatin (PubMed:29109278).  The dpb3-dpb4 dimer is also required for the recruitment of sir2 to heterochromatin (PubMed:29109278).
What are the official names of this protein?
DNA polymerase epsilon subunit D, DNA polymerase II subunit D.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBIB_SHESA
Sequence: MTLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKGKSGGERLKLAMQELGPVYIKLGQMLSTRRDLLSDEWANELAMLQDKVPPFDGALARQAIEAELKAPIESYFDDFDETPLASASISQVHTATLKSNGKAVVLKVLRPNVETKIQADLLLMSQTAKVIDYLLGEGNRLRPSEVIEDYRVTILGELNLKLEALNAIKLRNNFLDSDALYIPYVYEEFCYPRLMVMERIYGIPVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISREHPENPYYIGLDCGIMGTLSEVDKRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQLVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMAEQVGPKAMFKKVSTKLPYWSDKLPEFPELIYDNLKLGRKLLSSQQQMLDKYLKYQQQAHKSNYLLITSAILLICGTLLFNQDATLWSPYVCLISGAVLWIIGWRSRPKNRKF
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECO_RUBXD
Sequence: MALYRSRGIVLRSIRYGEADRILDIYTRDAGLVSCIAKGIRRTRSRFGARLEPFSCVDFMAYRGRTLDTITQAESLRSFRGVRERLDRLQAAAGMAGVLHALSGGTPDRRTFNLLYRALDALEKGEEGFGMIEASFGLKLAVLSGYAPRLDGCAECGGDVPGEGARFAPAAGGFLCRDCRSDAPPDSFPVPPGTLGRLRELAALPLAEAASGRGLEEALRRVVRAHVLAHAPGAASLATPAGTAGGRP
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: BIOB_BACC0
Sequence: MKQVQTKRDWKKLAYDVVEEKMITKEDAIAILEADDTEVLEIMNAAYIIRHHYFGKKVKLNMIINTKSGLCPEDCGYCSQSIISEAPIDKYAWLTQEKIVEGAHEAIRRKAGTYCIVASGRRPTDKEVNHVIGAVKEIRETTDLKICCCLGFLNEDQAGRLAEAGVHRYNHNLNTHANNYESICSTHTYDDRVDTVQKAKQAGISPCSGAIFGMGETIEERAEIAFELQRIDADSIPCNFLVAVKGTPLEGQKELTPVECLKVLAMMRFVNPTKEIRISGGREINLRSVQPIGLFAANSIFVGDYLTTAGQEPTADWGMIEDLGFEIEECAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RL4_GEOKA
Sequence: MPKVALYNQNGQTVGEIELNDAVFGIEPNKHVLFEAVIMQRASMRQGTHKTKNRAEVSGGGRKPWRQKGTGRARQGSIRAPQWRGGGTVFGPVPRSYSYKLPKKVRRLAIKSALSSKVLENDIVVLDQLSLEAPKTKEMVKILNNLSVDRKALIVTDELNENVYLSARNIPGVKVVAANGINVLDVLNHDKLVITKAAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PQQA_PSEAB
Sequence: MWTKPSFTDLRLGFEVTLYFANR
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.
Protein: PURA_LACH4
Sequence: MAAVAVVGGQWGDEGKGKITDFLSKDATMAVRSNGGNNAGHTIDIDGKEFKMRLIPSGIFAASKAAVIGNGVVINPEVMFGELDNLEKNGIDTSKLRISNRAHIIMPYDVKQDEYQEEAKGDRKIGTTKNGIGPTYMDKASRIGIRVCDLLEKDTFEEKLRLNLKVKNELFTKVYGKPALKLEDIFDKYYEYGQKMKKYVTDTSVLVNDALDNGEKVLFEGAQGTMLDIDEGTYPYVTSSNTISGGICSGIGMGANRLNTVIGVCKAYTTRVGEGPFPTELLDEVGDRIRDTAHEYGTVTGRPRRVGWFDSVALRHAKRVSGINGLSLNLLDVFSGFDKIKICTAYELDGKKIEYYPASLKELYRCKPVYEELPAWEEDITAAKKLDDLPENAQKFLNRVSELVGVPLVTVSVGPDREQTIVLKNPWER
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.