PharMolix/UniProtQA huggingface dataset:
Protein: KTHY_PARMW
Sequence: MSGRFIVLDGIDGCGKSTQLDHLLGWLPGSGLMPAGAELISTREPGGTPLGRSVRELLLHTRAEQAPAPTAELLLYAADRAQHVERLILPTLERGDWVISDRFSGSTMAYQGYGRGLDRQLIDQLERIATAGVQPDLTLWLTLPLEESLRRRQGDQADRIEAEGQVFLQRVIDGFAAIAEQRQWSAIAADRPPEAVSRALERELMDRLG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: DPP4_ASPFC
Sequence: MKWSILLLVGCAAAIDVPRQPYAPTGSGKKRLTFNETVVKRAISPSAISVEWISTSEDGDYVYQDQDGSLKIQSIVTNHTQTLVPADKVPEDAYSYWIHPNLSSVLWATNYTKQYRYSYFADYFIQDVQSMKLRPLAPDQSGDIQYAQWSPTGDAIAFVRDNNVFVWTNASTSQITNDGGPDLFNGVPDWIYEEEILGDRFALWFSPDGAYLAFLRFNETGVPTFTVPYYMDNEEIAPPYPRELELRYPKVSQTNPTVELNLLELRTGERTPVPIDAFDAKELIIGEVAWLTGKHDVVAVKAFNRVQDRQKVVAVDVASLRSKTISERDGTDGWLDNLLSMAYIGPIGESKEEYYIDISDQSGWAHLWLFPVAGGEPIALTKGEWEVTNILSIDKPRQLVYFLSTKHHSTERHLYSVSWKTKEITPLVDDTVPAVWSASFSSQGGYYILSYRGPDVPYQDLYAINSTAPLRTITSNAAVLNALKEYTLPNITYFELALPSGETLNVMQRLPVKFSPKKKYPVLFTPYGGPGAQEVSKAWQALDFKAYIASDPELEYITWTVDNRGTGYKGRAFRCQVASRLGELEAADQVFAAQQAAKLPYVDAQHIAIWGWSYGGYLTGKVIETDSGAFSLGVQTAPVSDWRFYDSMYTERYMKTLESNAAGYNASAIRKVAGYKNVRGGVLIQHGTGDDNVHFQNAAALVDTLVGAGVTPEKLQVQWFTDSDHGIRYHGGNVFLYRQLSKRLYEEKKRKEKGEAHQWSKKSVL
What is the function of this protein?
Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.  Contributes to pathogenicity.
What are the official names of this protein?
Probable dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DppIV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Secreted.
Protein: CUBT_TRIIF
Sequence: MTTLRVLLAVCCAAYCILAEDVTVPANGELKLMPDQKAGGRLEGQWKISTPDHYYLIVSCGLWSSASGTCKDKILITQGGKTTEVCGEGKNSFYVQQDTNLNTAEIIILTNTPDARAMCTVYSAEKPKEENTF
What is the function of this protein?
May function as an antimicrobial peptide and may be related to the innate defense of the insect in the salivary glands.
What are the official names of this protein?
Triatox, Venom CUB domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the venom CUB family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2284_ENT38
Sequence: MSITAKSVYRDTGNFFRNQFITFLLIALLCALITVVLGHAFSPSDEQIASLSQGDNLAGSVGLFDLVQNMTPEQQQILLRASAASTFSGLIGNAIMAGGVLLMVQLVSAGQRVSALRAIGASAPVLPKLFILIFLTTLLVQMGIMLVVVPGVLLAIILSFAPVMLVQDKMGIFTAMRSSIKLAWSNMRLVAPAVIGWLLAKTLLLLFAPNFAVLTPNIGAVVANTISNLISAVLLVYLFRLYTLIRQ
What are the official names of this protein?
UPF0259 membrane protein Ent638_2284.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y671_THEP1
Sequence: MMDWKEAEELACKFLKKKGYKILERNYRTKYGEIDIVARDGREIVFVEVKSGSGKVDPLERIDLKKVRNLEQTARFYMIQNKLKGPARVDFVRVTPEGIDHFEGIWLG
What are the official names of this protein?
UPF0102 protein Tpet_0671.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: YCF45_CYACA
Sequence: MLIFNDLRHFLPVVPRFVYKSLKKHPRKFGLTEIVLDNGRRAEGRWREKTENLTHKKITKKHLLRCIKKIGIFNEDNRAGIYQTLHRISCIKNRYGNIVGLTYRIGREFIGIGPIIRDLIESNQSTLLIGRPGIGKTSFIREISRILSNEIMKRVIIVDSANEISGEGCCPHISTGKARRMEVQSINSQHEVMIEAIENHTPEIIIIDEIGTEYESQAAISISQRGIRLIGSAHSSDLFNLAKNPTLCKLVGGIESVTLSDTQAILRKTKKTILERKGCSCFNATIEINKKRTVKVYTSVEQSIDAILEGRVNNSQIRSMKLNGEITISLNYQDE
What are the official names of this protein?
Uncharacterized protein ycf45.
What is the protein family that this protein belongs to?
Belongs to the ycf45 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPPH_BRASO
Sequence: MTRYEDLPYRTCVGIALINSEGLVFIGRRAGGIEHVDDTHVWQMPQGGVDPGEDAWEAAKRELYEETSVRSVEKLAEIDDWLTYDIPRTVAGRAWKGRYRGQRQKWFALRFTGKDSEIDVEHPGGGHHKAEFITWRWEPLQNLPTLIVPFKRPVYERVAKEFATLAGG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: MTOX_ECOLC
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEDDPIFVRSGVINLGPADSAFLANVAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: RPOB_PROMS
Sequence: MSSSALQVAKTATYLPDLVEVQRASFKWFLEKGLIEELQNFSPISDYTGKLELHFIGEEYRLKRPRHDVEEAKRRDATFASQMYVTCRLINKETGEIKEQEVFIGELPLMTERGTFIINGAERVIVNQIVRSPGVYFKDELDKNGRRTYNANVIPNRGAWLKFETDKNNLLYVRVDKTRKINAHVLMRAMGLSDNDVVDKLRHPEFYQNSIDSANDEGINSEDQALLELYKKLRPGEPPSVSGGQQLLNSRFFDPKRYDLGRVGRYKINKKLRLTVPDDVRTLTHEDVLSTIDYLINLELDIGGASLDDIDHLGNRRVRSVGELLQNQVRVGLNRLERIIKERMTVGETDSLTPAQLVNPKPLVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRISALGPGGLTRERAGFAVRDIHPSHYGRLCPIETPEGPNAGLINSLATHARVNEYGFIETPFWEVKNGKVNKEGNPVYLSADLEDECRVAPGDVATDKDGNIIADLIPVRYRQDFEKVPPHQVDYVQLSPVQVISVATSLIPFLEHDDANRALMGSNMQRQAVPLLRPERPLVGTGLESQVARDSGMVPITKVNGTVSYVDANEIVVKDDHGNEHFHYLQKYQRSNQDTCLNQRPIVKIGDKVISGQVLADGSACEGGEIALGQNVLIAYMPWEGYNYEDAILVSERMVTDDLYTSVHIEKYEIEARQTKLGPEEITREIPNISEESLNNLDEMGIIRIGAFVESGDILVGKVTPKGESDQPPEEKLLRAIFGEKARDVRDNSLRVPKTEKGRVLDVRIYTREQGDELPPGANMVVRVYVAQRRKIQVGDKMAGRHGNKGIISRILPREDMPYLPDGTPVDIVLNPLGVPSRMNVGQVFELLMGWAAANLNCRVKVVPFDEMYGAEKSHQTVQAFLEEASKQPGKAWVYNPEDPGKLLLKDGRTGEPFDQPVAVGYSHFLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRLGEMEVWALEAYGAAYTLQELLTVKSDDMQGRNEALNAIVKGKPIPRPGTPESFKVLMRELQSLGLDIGVYTDEGKEVDLMQDINPRRNTPSRPTYESLGTSEYEED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TYPH_MYCPI
Sequence: MNIIEIIELKKNKKKLSQDQINFCISGLVNKSIPDYQISALLMAIWFNGLDDNELYFLTKAMIDSGKIYKFHPEYKKILIDKHSTGGIGDKVSIALRPILVSFDLGVAKLSGRGLGFTGGTIDKLESINVNTDIDLKNSKKILNIANMFIVGQTNDIVPADKLLYALRDVTGTVDSLPLIAASILSKKFALESDYIFIDIKYGQGAFCHDIETAKKISNIMKNLAKKFKRKVYFVLSDMNEVLGNTVGNAIEVKEAIDFLKNNSDVGTYFKKLMFDLVTLILLKTKKCKTKKEAKEKINYVLENKIAFNNFCNWIELQNGNIAKIKNDTFFKPKYWTNIAAWKSGKISYKSIIELAEIGVDLGSGRRKKEDKIDFQAGIYLHAKSNEKIKIKDKILTLYSSKPIKQDLIDKAKKIIKIS
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: RL332_MYCA1
Sequence: MPRNEIRPLVKLRSTAGTGYTYITRKNRRNDPDRLVLRKYDPVVRRHVDFREER
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: Y7036_VIBC1
Sequence: MGRSFEVRKASMAKTAGAKIKVYSKYGKEIYMCAKNGGGDPDMNLSLKHLIAKAKKDQVPAHVIDKAIDKANGGGGEDYTPARYEGFGPGGTSVIVDCLTDNGNRTFQDVRQCFVKVGAKIGVEGSVSHMFDHQAVFQFKGEDDEIILETLMMEDVDVTDVELEDGVITVFAPHTEFFKTKTALNGAFPDLTIDVEEITFVPQTHTPVAGEDAEKFQKFLDLLDDCDDVQQVYHNGEL
What are the official names of this protein?
Probable transcriptional regulatory protein VIBHAR_07036.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGFB2_XENLA
Sequence: MHYYVLFTFLTLDLAPVALSLSTCSALDMDQFMRKRIEAIRGQILSKLKLNSPPEDYPEPGEVSQDVISIYNSTRDLLQEKANERATSCERERSEDEYYAKEVYKIDMLPYYTSENVIPPSYTTPYFRIVRFDVSSMEKNASNLVKAEFRVFRLMNTKARVSEQRIELYQILKSKDLASPTQRYIDSKVVKTRAEGEWLSFDVTEAVNEWLHHKDRNLGFKISLHCPCCTFIPSNNYIIPNKSEELETRFAGIDDAYMYAGGDSKSKTGRKKHTGRTPHLLLMLLPSYRLESQQSSRRKKRALDAAYCFRNVQDNCCLRPLYIDFKKDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLDSLTILYYIGNKPKIEQLSNMIVKSCKCS
What is the function of this protein?
Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity).  Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains remain non-covalently linked rendering TGF-beta-2 inactive during storage in extracellular matrix (By similarity).  At the same time, LAP chain interacts with 'milieu molecules', such as ltbp1 and lrrc32/garp, that control activation of TGF-beta-2 and maintain it in a latent state during storage in extracellular milieus (By similarity).  Once activated following release of LAP, TGF-beta-2 acts by binding to TGF-beta receptors (tgfbr1 and tgfbr2), which transduce signal (By similarity).
What are the official names of this protein?
Transforming growth factor beta-2 proprotein.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix. SUBCELLULAR LOCATION: [Transforming growth factor beta-2]: Secreted.
Protein: UT14A_HUMAN
Sequence: MTANRLAESLLALSQQEELADLPKDYLLSESEDEGDNDGERKHQKLLEAISSLDGKNRRKLAERSEASLKVSEFNVSSEGSGEKLVLADLLEPVKTSSSLATVKKQLSRVKSKKTVELPLNKEEIERIHREVAFNKTAQVLSKWDPVVLKNRQAEQLVFPLEKEEPAIAPIEHVLSGWKARTPLEQEIFNLLHKNKQPVTDPLLTPVEKASLRAMSLEEAKMRRAELQRARALQSYYEAKARREKKIKSKKYHKVVKKGKAKKALKEFEQLRKVNPAAALEELEKIEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLSKNKELTQKLQVASESEEEEGGTEDVEELLVPDVVNEVQMNADGPNPWMLRSCTSDTKEAATQEDPEQLPELEAHGVSESEGEERPVAEEEILLREFEERRSLRKRSELSQDAEPAGSQETKDSGSQEVLSELRVLSQKLKENHQSRKQKASSEGTIPQVQREEPAPEEEEPLLLQRPERVQTLEELEELGKEECFQNKELPRPVLEGQQSERTPNNRPDAPKEKKKKEQMIDLQNLLTTQSPSVKSLAVPTIEELEDEEERNHRQMIKEAFAGDDVIRDFLKEKREAVEASKPKDVDLTLPGWGEWGGVGLKPSAKKRRRFLIKAPEGPPRKDKNLPNVIINEKRNIHAAAHQVRVLPYPFTHHWQFERTIQTPIGSTWNTQRAFQKLTTPKVVTKPGHIINPIKAEDVGYRSSSRSDLSVIQRNPKRITTRHKKQLKKCSVD
What is the function of this protein?
May be required for ribosome biogenesis.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 14 homolog A, Antigen NY-CO-16, Serologically defined colon cancer antigen 16.
What is the protein family that this protein belongs to?
Belongs to the UTP14 family.
Protein: RGA4_SOLBU
Sequence: MAEAFLQVLLENLTSFIGDKLVLIFGFEKECEKLSSVFSTIQAVLQDAQEKQLKDKAIENWLQKLNSAAYEVDDILGECKNEAIRFEQSRLGFYHPGIINFRHKIGRRMKEIMEKLDAISEERRKFHFLEKITERQAAAATRETGFVLTEPKVYGRDKEEDEIVKILINNVNVAEELPVFPIIGMGGLGKTTLAQMIFNDERVTKHFNPKIWVCVSDDFDEKRLIKTIIGNIERSSPHVEDLASFQKKLQELLNGKRYLLVLDDVWNDDLEKWAKLRAVLTVGARGASILATTRLEKVGSIMGTLQPYHLSNLSPHDSLLLFMQRAFGQQKEANPNLVAIGKEIVKKCGGVPLAAKTLGGLLRFKREESEWEHVRDNEIWSLPQDESSILPALRLSYHHLPLDLRQCFAYCAVFPKDTKMIKENLITLWMAHGFLLSKGNLELEDVGNEVWNELYLRSFFQEIEAKSGNTYFKIHDLIHDLATSLFSASASCGNIREINVKDYKHTVSIGFAAVVSSYSPSLLKKFVSLRVLNLSYSKLEQLPSSIGDLLHLRYLDLSCNNFRSLPERLCKLQNLQTLDVHNCYSLNCLPKQTSKLSSLRHLVVDGCPLTSTPPRIGLLTCLKTLGFFIVGSKKGYQLGELKNLNLCGSISITHLERVKNDTDAEANLSAKANLQSLSMSWDNDGPNRYESKEVKVLEALKPHPNLKYLEIIAFGGFRFPSWINHSVLEKVISVRIKSCKNCLCLPPFGELPCLENLELQNGSAEVEYVEEDDVHSRFSTRRSFPSLKKLRIWFFRSLKGLMKEEGEEKFPMLEEMAILYCPLFVFPTLSSVKKLEVHGNTNTRGLSSISNLSTLTSLRIGANYRATSLPEEMFTSLTNLEFLSFFDFKNLKDLPTSLTSLNALKRLQIESCDSLESFPEQGLEGLTSLTQLFVKYCKMLKCLPEGLQHLTALTNLGVSGCPEVEKRCDKEIGEDWHKIAHIPNLDIH
What is the function of this protein?
Disease resistance protein.  Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via a direct or indirect interaction with this avirulence protein.  That triggers a defense system which restricts the pathogen growth.
What are the official names of this protein?
Putative disease resistance protein RGA4, RGA4-blb.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: PCKG_GEOSL
Sequence: MSYELPNNEKLLKWVEEVAILCEPDRIHWCDGSQEEYDELCELLVQNGTFRKLNPEKRPNSYLAWSDPIDVARVEDRTFICSLSKQDAGPTNNWMNPKEMKEKLLGLFKGCMKGRTMYVIPFSMGPLGSPIAKIGVEITDSPYVVVNMRIMTRMGKKVLDILGEQGEFVPCLHSVGAPLEQGQKDSTWPCNKEKYIVHFPEERSIWSFGSGYGGNALLGKKCLALRIASKQGKDEGWLAEHMLILGVESPTGDKTYVGAAFPSACGKTNFAMLIPPKPLQDKGWKVTTIGDDIAWIKPGPDGQVYAINPEYGYFGVAPGTNVKTNPNAMASCSANTIFTNVALTPDDDVWWEGMTDEPPAQLTDWQGNPWTPDCGRPAAHPNARFTSPASQCPSIDPDWENPKGVPMSAFIFGGRRKDTVPLVYQAFNWSNGVYLAATLGSETTAAAVGAVGNVRRDPFAMLPFCGYHMADYFGHWLQFGRSIPRPPRIFSVNWFRKDANGKFIWPGYGDNMRVLKWIVERVQGKAGAVESPLGWMPRYEDMDWDGLDMPREKFNELTSVDRDVWQNELISHEELFVKLFDRLPKEFLHMRELILSSLWRSPEHWEQIGDVHPEGWNE
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_BACHK
Sequence: MIDVNNFEYMKIGLASPDKIRSWSYGEVKKPETINYRTLKPEKDGLFCERIFGPQKDWECHCGKYKRVRYKGVVCDRCGVEVTRAKVRRERMGHIELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEVIYFASYVVTESGDTPLDKKQLLSEKEYRAYRDRYGSTFQAAMGAEAIKKLLQDIDLDKEVDFLKEELKTAQGQRRTRAIKRLEVLEAFRNSGNEPSWMILDVLPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPSIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKMYQCGLPKEMALELFKPFVMKELVEKGLAHNIKSAKRKIERVQPEVWDVLESVIKEHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVCTAYNADFDGDQMAVHVPLSSEAQAEARLLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLEREGAIGEGMVFKDANEALLAYQNGYVHLHTRVAVAASAVNNATFTEEQKNMLLLTTVGKLIFNEILPESFPYINEPTNSNLEKETPAKYFVEKGANIKEIIASREEVAPFSKKILGNIIAEVFKRFKITETSRMLDRMKNLGFKYSTKAGITVGVSDILVLGEKDEILHEAQAKVDNVIKQFRRGLITEEERYDRVISIWSNAKDVIQGKLMKSLNKRNPIFMMSDSGARGNASNFTQLAGMRGLMANPSGRIIELPIKSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIVREDDCGTDRGLLIGAIKEGNEVIESLYDRLVGRFARKTVKHPETGEVLVAENQLITEDIAHIVENSGVETVNIRSAFTCNTRHGVCKKCYGRNLATGTDVEVGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRIQEIFEARNPKGQAVISEIDGVIAAINDVKDRQEVVVQGEVEARTYAIPYGARLKVIPGQKISHGKELTEGSIDPKELLKVTDITAVQEYLLREVQKVYRMQGVEIGDKHVEVMVRQMLRKVRVSDAGETDVLPGTLLDIHQFTDANAKVLLQGKQPATARPVLLGITKASLETDSFLSAASFQETTRVLTDAAIKGKRDELLGLKENVIIGKLVPAGTGMNRYRKVDLVKTTQDDMNVENDEVYVEQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RF3_RALSO
Sequence: MPVSTLQQEIRRRRTFAIISHPDAGKTTLTEKLLWFGGAIQMAGAVRARKASRHATSDWMELEKQRGISVTSSVMQFPYRNDGGDYIVNLLDTPGHEDFSEDTYRTLTAVDSAVMVIDSVNGVEAQTIKLLNVCRLRSTPILTFINKLDREGRAPIELLDEIENVLQIQCAPMTWPIGMGKSFRGVYHLVNDTVQLFDPKAETEKGATAGMIQGLDNPELDRVLGSQAEELRIDIELVRGASHTFDKDLFLAGKQCPVYFGSAVNNFGVQSLLDALVGLSPEPLARATQTREVAPLEDKFTGFVFKIQANMDPKHRDRIAFVRVCSGRFERGMKLLQVSTGKTVAINNAITFMAQDRNTTEEAYAGDIIGVPNHGTIRLGDAFTEGEPLRFTGIPSFAPEYFRRARLNNPLKTKQLQKGLQQLAEEGATQMFRPLASNDLVLGAVGTLQFDVVAHRLEYEYGVDAIFEPHECATARWLKGKPEDIDKLIDKAGHNVAVDGAGDYVYLAPSQVNLRLTQERFPDIQFMETREVV
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y623_METJA
Sequence: MRDGEGIWGRGRTGGHAHPKEAMHTTFFILGGTMLIGVISDTHLYDRAFELPKAVFDEFSNVDLIIHCGDVTDKEILDSLKDLAKVVAVKGNMDYLNLPRKEILEINDIKIGVIHGDVVYPRGDRLKLRLLGKEMGVDVLISGHTHTPFIDDCRDILLLNPGSPTVPRCPLKSIMKLSVEDKLEAKLIPIEE
What are the official names of this protein?
Putative metallophosphoesterase MJ0623.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. YfcE family.
Protein: HPF1_DANRE
Sequence: MAGRGKRKPRSLPQTETPNGEVKKAKEGLKDDKTSVGEEMREEVERLYKLRMPDDFFQFWDFCEGLNADCPQDALKNTLGLQLVGPFDILSKKHKNSSSQPNFHLHWRYFYDPPEFQTIIQGNADTQHHMGYFRDLPDALPVFIGENEAKKGYTITQLGDNIFAAVLLFLQKKKKEKRQQKDDAALNRLEEDLKREAERLGLPLEQKTKSMKQRERKVVTKTFHGAGIVVPVDKNDVGYRELPESDASLKKICKAIAEAKDDEERMKAFAPIQEMITFVQFANDECDYGMGYELGIDLFCYGSHYFFKVVRQLLPMAYNLLKRGLFGEILEAHLASRSQDNLDQLAAV
What is the function of this protein?
Cofactor for serine ADP-ribosylation that confers serine specificity on parp1 and parp2 and plays a key role in DNA damage response.  Initiates the repair of double-strand DNA breaks: recruited to DNA damage sites by parp1 and parp2 and switches the amino acid specificity of parp1 and parp2 from aspartate or glutamate to serine residues, licensing serine ADP-ribosylation of target proteins.  Serine ADP-ribosylation of target proteins, such as histones, promotes decompaction of chromatin and the recruitment of repair factors leading to the reparation of DNA strand breaks.  Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage.  Hpf1 acts by completing the active site of parp1 and parp2: forms a composite active site composed of residues from Hpf1 and parp1 or parp2.  While hpf1 promotes the initiation of serine ADP-ribosylation, it restricts the polymerase activity of parp1 and parp2 in order to limit the length of poly-ADP-ribose chains.  Hpf1 also promotes tyrosine ADP-ribosylation, probably by conferring tyrosine specificity on parp1.
What are the official names of this protein?
Histone PARylation factor 1.
What is the protein family that this protein belongs to?
Belongs to the HPF1 family.
What are the subcellular locations of this protein?
Chromosome. Nucleus. Note=Localizes to DNA damage sites; chromatin localization is dependent on parp1 and parp2.
Protein: MVP_BYDVR
Sequence: MAQEGGAVEQFGQWLWSNPIEQDPDDEMVDAREEEGQILYLDQQAGLRYSYSQSTTLKPTPPGQSNSAPVYRNAQRFQTEYLSPTTVTRSQVSVLSLSHTRPQLRPALSLLNSTPRANNQPWVATLIPSQSAGPPQRSSEPKRLTGRNSRNQR
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier (By similarity).
What are the official names of this protein?
Movement protein, MP, 17 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the luteoviruses movement protein family.
Protein: PSBJ_PROM2
Sequence: MSKKLKGPDGRIPDRLPDGRPAVAWERRWTEGTLPLWLVATAGGIAVIFVLGIFFYGSYQGVGAGG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: GCK_THEMA
Sequence: MFDPESLKKLAIEIVKKSIEAVFPDRAVKETLPKLNLDRVILVAVGKAAWRMAKAAYEVLGKKIRKGVVVTKYGHSEGPIDDFEIYEAGHPVPDENTIKTTRRVLELVDQLNENDTVLFLLSGGGSSLFELPLEGVSLEEIQKLTSALLKSGASIEEINTVRKHLSQVKGGRFAERVFPAKVVALVLSDVLGDRLDVIASGPAWPDSSTSEDALKVLEKYGIETSESVKRAILQETPKHLSNVEIHLIGNVQKVCDEAKSLAKEKGFNAEIITTSLDCEAREAGRFIASIMKEVKFKDRPLKKPAALIFGGETVVHVKGNGIGGRNQELALSAAIALEGIEGVILCSAGTDGTDGPTDAAGGIVDGSTAKTLKAMGEDPYQYLKNNDSYNALKKSGALLITGPTGTNVNDLIIGLIV
What is the function of this protein?
Involved in the degradation of serine via 3-hydroxypyruvate.  Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate.
What are the official names of this protein?
D-glycerate 2-kinase, GCK.
What is the protein family that this protein belongs to?
Belongs to the glycerate kinase type-1 family.
Protein: AZOR_POLNA
Sequence: MSKLLHIDSSILGSNSVSRQLTAQIVASWRAAHPATEVSYLDLAMDSPSHLSVESLGFRLPAGTADLSEVQQRENAISEALVSQFMAADVLVIGAPLYNFSIPSQLKAWIDRVAQAGRTFKYTEKGPVGLAGGKTIIVASARGGMYSTSDAGNAMEHQESYLKTVFGFFGVTDVRFVRAEGLAMGEAAKAAALAAAQVEILAQTHSAANQPQAVLVA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RL18_HYDCU
Sequence: MDKKATRLRRAKKTRAKLGSQDRARLCVHRTPKHIYAQIISSDGSSVVASCSTVQADIKKQVAFGGNKEAAELVGKSIAEKAKAAGIESVAFDRSGFKYHGRVQVLADSARENGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: AC4CH_ECO27
Sequence: MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRFEDDGYFCTIEVTATSTVTLDTLTEKHAKQENMTLTELKKVIADIYPDQTQFYVIEFKCL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: GATA5_BOVIN
Sequence: MYQSLALAPSPGQTAYADSGAFLHTPGAGSPVFVPPARVPSMLPYLPACEPGPQAPAITAHPGWAQAAAADSSAFGSGSPHAPAAPPPGTTAFPFAHSSPGPGGGTGTRDNGAFQGAMLAREQYPAALGRPVSSSYPTAYPAYMSAEVAPSWTSGPLDGSVLHSLQGLPAGLPGRRAPFAAELLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRAGLCCTNCHTTTTTLWRRNVDGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNIAKTKGSSGSSGHTTASPQASVPDPEVSAATLKPEPSLASPSCPGPSVTSQGSAQVDDPLAPSHLEFKFEPEDFALPSAALGQQAGLGGALRQEAWCALALA
What is the function of this protein?
Transcription factor required during cardiovascular development.  Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity.  Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (By similarity).
What are the official names of this protein?
Transcription factor GATA-5, GATA-binding factor 5.
What are the subcellular locations of this protein?
Nucleus.