PharMolix/UniProtQA huggingface dataset:
Protein: AROA_PELTS
Sequence: MDLHVGKSRGLRGTVAVPGDKSISHRAVMLGALASGETIIENFLPGEDCLSTIDCFRKLGVEINGPDNNTVRVRGRGLDGLSEPVDVLDTGNSGTTMRLILGVLAGQPFFSVITGDSSLRRRPMGRVTGPLISMGAKIDGRQNGNLAPLAVRGGTLRPINFVSPVASAQVKSAVLLAGLFTDGVTAVTEAYRTRDHTERMLRAFGAGVEVSEGTVAVKGRPRLTGRKVKVPGDISSAAFLLVAASLIPGSDLTLTGVGVNPTRIGIIEVLSSMGAEIRLFNLREEEEPVADIRVRYNGRLCGTAVGGEIIPRLIDEVPALAVAAALAEGKTVIRDAAELKVKESDRIAAVAGMLAKFGADVEELPDGLLVRGSRALKGCVCESHGDHRIAMAAAVAGLLAEGKTIVRGAECISVSFPGFSDLLAKVMVDWQ
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_STAES
Sequence: MARIAGVDIPREKRIVISLTYVYGIGTSTANKIVEEANVSADTRVKDLTDDELGRIREVVDGYKVEGDLRREQNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NARF_DROME
Sequence: MSRLSRALQLTDIDDFITPSQICIKPVQIDKARSKTGAKIKIKGDGCFEESESGNLKLNKVDISLQDCLACSGCITSAEEVLITQQSREELLKVLQENSKNKASEDWDNVRTIVFTLATQPILSLAYRYQIGVEDAARHLNGYFRSLGADYVLSTKVADDIALLECRQEFVDRYRENENLTMLSSSCPGWVCYAEKTHGNFLLPYVSTTRSPQQIMGVLVKQILADKMNVPASRIYHVTVMPCYDKKLEASREDFFSKANNSRDVDCVITSVEVEQLLSEAQQPLSQYDLLDLDWPWSNVRPEFMVWAHEKTLSGGYAEHIFKYAAKHIFNEDLKTELEFKQLKNRDFREIILKQNGKTVLKFAIANGFRNIQNLVQKLKREKVSNYHFVEVMACPSGCINGGAQIRPTTGQHVRELTRKLEELYQNLPRSEPENSLTKHIYNDFLDGFQSDKSYDVLHTRYHDVVSELSISLNINW
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins (By similarity).
What are the official names of this protein?
Probable cytosolic Fe-S cluster assembly factor CG17683.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: CAP12_FLADA
Sequence: MKTRIFIGSSKEGLEIAEYIKLQLGTKYECYLWTDDIFKFNESFLYTLLKEASLFDFGILVATKDDLSTIRDKSFDTPRDNVIFEFGLFLGRLGPSRAFVIQESGAKLPTDLLGITVPQFEKTIPLANSTSLNNEIERISKTIDEKITLGELGLLPSTVLAIGYFYNFVSIVCESIHTKSDIKVDDAIFKKFELNIVIPKDLDADIKKRATVYFKSKTLKEIQFETSSRNFPVFVTYDNQSKDVLKLYDMPTTLGGIDKAIEMFMRKGHIGKTSQQKLLEERELRNFQTTLQNLIDNDAFCRNIVKIIQEE
What is the function of this protein?
The effector protein for this CBASS system.  Binds c-di-GMP, does not bind cUMP-AMP (PubMed:32877915).  Upon activation by c-di-GMP forms filaments which hydrolyze NAD(+); filament formation is required for enzyme activation (By similarity).
What are the official names of this protein?
CD-NTase-associated protein 12, Cap12, NAD(+) hydrolase, TIR-STING, FdSTING.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the bacterial STING family.
Protein: Y6939_DICDI
Sequence: METKYHEYDDVQTKDTPSNKYSLNENRGDLIFLIMEIIGESCNSIYDSFTLDAPQFAFRGIDKTLSKDGEIGKLITIIKNLIKEQSYLLKSPMTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSYNNNNINDNNNSSNNNNNNLEYNTKGGEYISSNQSSPLSIYSTPPNPSSYVSSPLNQPANNTEAFQINGNELDAAQIKIKQLELELQKFKEAGALFAMNKINNSSAPPPPPKACAPPPPPPPPPPITVVKQPSFLMKKGVNNNNNNNNNNNSSNTNDSNNTNNTKPQPTFNFADVLLNRPQLKRVSKDRSPGGTPAKEPKNKSGSVEDALLKAIVSKFKHANSSPVKSHDDSSDSDFE
What are the official names of this protein?
Uncharacterized protein DDB_G0286379.
Protein: RL6_CAUVC
Sequence: MSRIGKKAVAIPSGVQVTLAGQTVTVKGPKGQLSWTIADEVEVKQEGAELLLAPRVDTKRAKGMWGLSRTLVANMVHGVTVGFEESLELVGVGYRAAMKGTALSLQLGFSHDVDVAAPAGVTFAVPKQTEIKIAGIDKQAVGEIAAKIRRIRPPEPYKGKGVRYAGEKVRRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SECB_EHRCJ
Sequence: MSYKLKVKGQYIKDLSFENQNSPQIFVMISKTPPEINISVNVSSVSLPVKAQDQENGQSLDNKVEPLYEVTLQVNAEARVGTTVAFICEVKYCGVFSVENSDASNGEELSQQDMRDMLLISAPSILFPFVRELISRITATGGFPPLMLDVVDFKAMYESQIKQNAAEQNDNGQHTEK
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNA_ECOLI
Sequence: MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWVERIAQLSPDVIFSFYYRHLIYDEILQLAPAGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACTARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA, Polymyxin resistance protein PmrI.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: PCKA_CUCSA
Sequence: MENEGKDNGEFSFVSDGGAETGRRGLPKIHTEKNAPTTERDICHDDSTTPMRARTLEHLHSLQKKRSTPTTPLTDSQGVFSPVSEAERQKQQLISISASLASLTRETGPKLVKGDPEKKKEAHKASVLDHLHFGEPILNLSDSALKSTHILYNPSPAELYEQAIKYEKGSFITSTGALATLSGAKTGRSPIDKRVVKDDTTEKELWWGKGSPNIEMDEHTFLINRERAVDYLNSLDKVFVNDQFLNWDPENRIKVRIVSARAYHSLFMHNMCIRPTAGELEDFGTPDFTIYHAGQFPCNRYTHYMTSSTSIDMNLDRKEMVILGTQYAGEMKKGLFSLMHYLMPMRQILSLHSGCNMGKNGDVALFFGLSGTGKTTLSTDHNRYLIGDDEHCWSDNGVSNIEGGCYAKCIDLSREKEPDIWNAIKFGTVLENVVFDEHTREVDYSEKSVTENTRAAYPIEYIPNAKIPCVGPHPKNVILLACDAFGVLPPVSKLSLPQTMYHFISGYTALVAGTEEGVKEPQATFSACFGAAFIMLHPSRYAAMLAEKMKKHGATGWLVNTGWSGGSYGSGNRIKLAYTRKIIDAIHSGALLEANYSKTRVFGLEIPDAIEGVPSHILDPINTWSDKDGYHETLLKLGGLFKKNYEGIHTYQVERDSELAEEILAAGPTL
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CZCD_CUPMC
Sequence: MGAGHSHDHPGGNERSLKIALALTGTFLIAEVVGGVMTKSLALISDAAHMLTDTVALAIALAAIAIAKRPADKKRTFGYYRFEILAAAFNALLLFGVAIYILYEAYLRLKSPPQIESTGMFVVAVLGLIINLISMRMLSSGQSSSLNVKGAYLEVWSDLLGSVGVIAGAIIIRFTGWAWVDSAIAVLIGLWVLPRTWILLKSSLNVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHIWALTSGKASLTVHVVNDTAVNPEMEVLPELKQMLADKFDITHVTIQFELAPCEQADAAQHFNASPALVGSKSLAAGGN
What is the function of this protein?
Mediates a low-level metal ion resistance, probably by efflux of cations from the cytoplasm into the periplasm.  Also mediates resistance to cobalt, cadmium and zinc via regulation of the Czc system.  May repress expression of the Czc system by an export of the inducing cations.  Binds and transports zinc.  Can also bind cobalt, copper and nickel.
What are the official names of this protein?
Metal cation efflux system protein CzcD, Cobalt-zinc-cadmium resistance protein CzcD.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DCDB_CLOB8
Sequence: MILSGKEILKNIGSNIIIEPFDEKKINPNSYNLSLHNELLVYENDILDMKTPNPTKVIKIPEDGLLLEPGKLYLGRTNEFTSTSKYVPMLEGRSSTGRLGLFIHVTAGFGDIGFSGYWTLEIFCVQPIKVYPNVEICQIYYHDIHGEYDLYSSGKYQNNKGIQPSLMYKDFEK
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ISPDF_RHOPB
Sequence: MSNSKRTAAIIVAGGRGLRAGAGGPKQYRSLAGQPVIFRAMQPFCTHAEIFAVQPVTSPDDAEMFKLAVAGLNYQPPAPGGATRQGSVRAGLEALAADAPDIVLIHDAARPFVDAALISRAIVAAQITGAAVPTIAVTDTIKQINAQGDVVATPDRARLRIAQTPQAFRFDVILEAHRRAAREGRDDFTDDAAIAEWAGLTVATFEGDVANMKLTTPEDFVREESRLGALLGDIRTGTGYDVHAFGDGDHVWLCGLKVPHNRGFLAHSDGDVGLHALVDAILGALADGDIGSHFPPTDPQWKGAASDKFLKYAVDRVTARGGRIANLEVTMICERPKIGPLREPMRQRIAEITGLPVARIAVKATTSERLGFTGREEGIAATASATLRLPWGTNGLAD
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: RPC9_CAVPO
Sequence: MEVKDANSALLSNYEVFQLLTDLKDQRRESGKMKHSAGQQNLNTITYETLKYLSKTPCRHQSPEIVREFLTAMKSHKLTKAEKLQLLNHRPMTAVEIQLMVEETEERFTEEEQIEALLHTVTHILPAEPEVEQMASTEAMEEEGPA
What is the function of this protein?
Accessory protein for the calcitonin gene-related peptide (CGRP) receptor.  It modulates CGRP responsiveness in a variety of tissues.
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC9, RNA polymerase III subunit C9, Calcitonin gene-related peptide-receptor component protein, CGRP-RCP, CGRP-receptor component protein, CGRPRCP.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HLDE_SULDN
Sequence: MKILKSFTPRILVIGDLMIDHYLWGNCERISPEAPVQIVDISKETTVLGGGGNVVNNLVALGAKVSVSGVIGNDENGVELLKLLREIDVNVDNIVIQEGRKTSKKSRVIAASQQILRYDKESKEEISKSSIEVILNSLAKDISRYDAVVLSDYSKGVLTKELCQGVISTCSKNGIKVLVDPKGSDYSKYSGAYLLTPNKKEAIQATKIDIKDKQSLKEALLKMKKDANLAISLITLSEDGVAIYDDEMKIFPTVAKEVFDVTGAGDTVIASIAFAISAGKSIEESAKFANLAAGVVVGKIGSATVSISEIEEYEASLHKSTSDAHIKGFEEIEAIVKRYKESGKKVVFTNGCFDILHVGHVKYLQIAKSFGDVLIVGLNSDTSVTRLKGPSRPVNIAEDRAYLLAALEAVDFVVPFEDDTPYELIKMIKPDTLVKGGDYEGKSVIGTEFAQELKLVDFVDGKSTTKTIQKIKGDLHV
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: SNG4_BOVIN
Sequence: MHIPESLQDLADSEAVQFLKRPKAITRIFAGVFSLIVFSSLLTDGYQNKTDNSELHCVLNSNSTACSIAVGAGLLAFLSSLAFLALDAHEVRLASTRFKTAFQLLDLILAVIWAGVWAVGFCFLANQWHRSPPRYFLLGSNSAKAAITFSFFSILVWIFQAYLAFQELRNDAPVPYKRSLDEGGVVLTSLSPPSAASPVNTPTTGPHGPSYASSSLSPYLSTPKAPRLAMMPDN
What are the official names of this protein?
Synaptogyrin-4.
What is the protein family that this protein belongs to?
Belongs to the synaptogyrin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HIS5_BACC7
Sequence: MIAIIDYGMGNIRSVEQALKHIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDVLEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISEYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_RHILO
Sequence: MQAKSIQAQSIQERLIVGLDLPTVREAEQAVRELDGVVSFYKIGYQLAFAGGLDFARELASGGTKIFLDMKLLDIDHTVAKGVENIVKMGMTMLTIHAYPKAMRAAVEAARGSDLCLLAVSVLTSMDEQDMIDVGYEYDPHTLVLRRSEQALHAGMGGIVCSAAEAEAVRRIVGPDMAVVTPGIRPAGSDHGDQKRVVTPAQAIRNGASHLVVARPIVAASDRRAAAQAILDEMRSA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: PGK1_RHINI
Sequence: MSLSNKLSIRDLNLKDKRVLIRVDFNVPMKDGAITNNNRIVQALPTVKYALDNGASAVILMSHLGRPNGEAVAKYSLKPVAAEVEKLLGKPVEFLNDCVGPDVEKACQSAKDGKVILLENLRFHIEEEGSAKVDGQKVKADAEAIKKFRASLTTLADIYINDAFGTAHRAHSSMVGVDLSQRAAGFLMQKELEYFAKALENPSRPFLAILGGAKVSDKIQLIENMLDKVNALIICGGMAFTFKKTLDNVKIGKSLFDEPGSKLVQNLVKKAAEKNVKIVFPVDFITADKFAPDASTGYATDDDGIPDGWQGLDCGERSNKLFREEILKSKTIVWNGPSGVFEFDAFSSGTKAVLDAVINATKEGATTIIIGGGDTATAALKWGAEGQVSHISTGGGASLELLEGKELPGVTALSSKN
What are the official names of this protein?
Phosphoglycerate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLZ2_ARATH
Sequence: MEVSMRKPYFIEEEDDGFVSLSEMEAGVSSPSCYNYPQSYYYNHHHHQYSVSSPRSGKFHDFRFDNSYYGYGQPHFLDSCFLCKKRLGDNRDIFMYRGDTPFCSEECREEQIERDEAKEKKQSLSTSVKAMRRNEKRSSSSSPTRSRNYAFRTGTVAAA
What is the function of this protein?
May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
What are the official names of this protein?
FCS-Like Zinc finger 2.
What is the protein family that this protein belongs to?
Belongs to the FLZ family.
Protein: MPK_PETHY
Sequence: MATPVEPPNGIRTPGKHYYSMWQSLFEIDTKYVPIKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTLRELKLLRHLRHENVIALKDVMMPIQRRSFKDVYLVYELMDTDLHQIIKSSQTLSNDHCQYFLFQLLRGLKYLHSANILHRDLKPGNLLINANCDLKICDFGLARTSSGKDQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFADVLGRKPVFPGTECLNQLKLIINILGSQREEDIEFIDNPKARKYIKSLPYSPGTPFSRLYPNAHPLAIDLLQRMLVFDPSKRISVMEALQHPYMSPLYDPNTDPPAQVPINLDIDEDLVEETIREMMWEEILHYHPEAAVALLWKLFYELLLVPSRHRP
What are the official names of this protein?
Mitogen-activated protein kinase homolog 1, PMEK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: NFAC2_MOUSE
Sequence: MDVPEPQPDPDGGDGPGHEPGGSPQDELDFSILFDYDYLNPIEEEPIAHKAISSPSGLAYPDDVLDYGLKPCNPLASLSGEPPGRFGEPDSIGFQNFLSPVKPAGASGPSPRIEITPSHELMQAGGALRGRDAGLSPEQPALALAGVAASPRFTLPVPGYEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNAGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVAPLPAASPQRSRSPSPQPSPHVALQDDSIPAGYPPTAGSAVLMDALNTLATDSPCGIPSKIWKTSPDPTPVSTAPSKAGLARHIYPTVEFLGPCEQEERRNSAPESILLVPPTWPKQLVPAIPICSIPVTASLPPLEWPLSNQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHVPEPSGRIVSLQAASNPIECSQRSAHELPMVERQDMDSCLVYGGQQMILTGQNFTAESKVVFMEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRVPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTEPSDEYEPSLICSPAHGGLGSQPYYPQHPMLAESPSCLVATMAPCQQFRSGLSSPDARYQQQSPAAALYQRSKSLSPGLLGYQQPSLLAAPLGLADAHRSVLVHAGSQGQGQGSTLPHTSSASQQASPVIHYSPTNQQLRGGGHQEFQHIMYCENFGPSSARPGPPPINQGQRLSPGAYPTVIQQQTAPSQRAAKNGPSDQKEALPTGVTVKQEQNLDQTYLDDVNEIIRKEFSGPPSRNQT
What is the function of this protein?
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF.  Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.
What are the official names of this protein?
Nuclear factor of activated T-cells, cytoplasmic 2, NF-ATc2, NFATc2, NFAT pre-existing subunit, NF-ATp, T-cell transcription factor NFAT1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin- mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
Protein: RS16_PHOLL
Sequence: MVTIRLARGGAKKRPFYQVVVTDSRSPRDGRFIERVGFFNPIATGKAEALRLDLDRIEHWIGLGATVSDRVSTLIKDAKKVA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: YJFL_ECO57
Sequence: MHILDSLLAFSAYFFIGVAMVIIFLFIYSKITPHNEWQLIKNNNTAASLAFSGTLLGYVIPLSSAAINAVSIPDYFAWGGIALVIQLLVFAGVRLYMPALSEKIINHNTAAGMFMGTAALAGGIFNAACMTW
What are the official names of this protein?
UPF0719 inner membrane protein YjfL.
What is the protein family that this protein belongs to?
Belongs to the UPF0719 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PITX3_MOUSE
Sequence: MEFGLLGEAEARSPALSLSDAGTPHPPLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGGFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGAPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVPGPPPAANLSPCQYAVERPV
What is the function of this protein?
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development.  In addition to its importance during development, it also has roles in the long-term survival and maintenance of the mdDA neurons.  Activates NR4A2/NURR1-mediated transcription of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.  Acts by decreasing the interaction of NR4A2/NURR1 with the corepressor NCOR2/SMRT which acts through histone deacetylases (HDACs) to keep promoters of NR4A2/NURR1 target genes in a repressed deacetylated state.  Essential for the normal lens development and differentiation.  Plays a critical role in the maintenance of mitotic activity of lens epithelial cells, fiber cell differentiation and in the control of the temporal and spatial activation of fiber cell-specific crystallins.  Positively regulates FOXE3 expression and negatively regulates PROX1 in the anterior lens epithelium, preventing activation of CDKN1B/P27Kip1 and CDKN1C/P57Kip2 and thus maintains lens epithelial cells in cell cycle.
What are the official names of this protein?
Pituitary homeobox 3, Homeobox protein PITX3, Paired-like homeodomain transcription factor 3.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEOD_ROSDO
Sequence: MTIHIGARPDQIAETVLMPGDPYRARWAAQTFLDGAELVNEVRGMLGFTGTYKGNRVTIQGSGMGMPSLSIYANELISSYNAQTLIRIGSCGGMQPHVAVRDVIIAMSATTITSPSSGIFREVNFAPTAHYDLLAAAVTAAKAKGTRTHVGGIYSSDVFYAERPDLDEQMVRHGILGVEMEAAELYTLAARHNRRALAILTVSDHLQTGEALPAEDREQTFGDMVEIALEAAFA
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: CAPH_STAAU
Sequence: MIKVMHIFSRMNRGGAELRTMDTMKLLNREFEFHVCATSGKRGELDDELESMGITIHYLDIKKFSFPFKFIKLLKKKNIDVVHSHILFMSGLIQLLSFSANVRNRITHFRTSKDSKEQYNKIRKARNKVLKAIIEIFSTKILYVSNIANRNLISMKLFPKKHKTIYNGFEISNINKNFKKEENSFIYVGRFIHTKNQLFLLDVIEILKKEFNTNIEITFVGNIQTDYGKKFLSIANERGLNKNIKVIGEVNNPLDYLKTSEYFLFPSELEGLPGALIEAHHHNCIVISSNIKENSEVNQYFKDSSFELELIPKTWASTIKKLISRKKHISFNDSNVFDINMTTQELKEIYMSKTL
What is the function of this protein?
Required for the biosynthesis of type 1 capsular polysaccharide.
What are the official names of this protein?
Capsular polysaccharide biosynthesis glycosyltransferase CapH.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: XYNC_NEOPA
Sequence: MKFLQIIPVLLSLTSTTLAQSFCSSASHSGQSVKETGNKVGTIGGVGYELWADSGNNSATFYSDGSFSCTFQNAGDYLCRSGLSFDSTKTPSQIGRMKADFKLVKQNISNVGYSYVGVYGWTRSPLVEYYIVDNWLSPSPPGDWVGNKKHGSFTIDGAQYTVYENTRTGPSIDGNTTFKQYFSIRQQARDCGTIDISAHFDQWEKLGMTMGKLHEAKVLGEAGNGNGGVSGTADFPYAKVYIGDGNGGGASPAPAGGAPAGGAPAGNDQPQGPQGQQPPQGQQPPQGQQPPQGQQPPQGQQPPQGNDQQGQQPPQGQQPPQGNDQHQGQHPPQPQGPQGGNPGGSDFNNWSQGGSPWGGNQGGSPWGGNQGGNPWGGNQGGSPWGGNQGGSPWGQGNQGGNPWGGNQGGSPWGGNQGGNPWGGNQWGAPQNAAAPQSAAAPQNASDGGNCASLWGQCGGQGYNGPSCCSEGSCKPINEYFHQCQK
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase C, Xylanase C, 1,4-beta-D-xylan xylanohydrolase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SMG_SALCH
Sequence: MFDVLMYLFETYIHNEAELRVDQDRLERDLTDAGFDREDIYNALLWLEKLADYQDGLAEPMQLASDPLSMRIYTVEECERLDASCRGFLLFLEQIQVLNLETREMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: MPRA_MYCUA
Sequence: MSVRILVVDDDRAVRESLRRSLSFNGYTVELAHDGVEALEMIASDRPDALVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTKLEDDEAADSVAMTFSDLSLDPVTREVTRGARRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
What is the function of this protein?
Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host.  Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region (By similarity).
What are the official names of this protein?
Response regulator MprA, Mycobacterial persistence regulator A.
What are the subcellular locations of this protein?
Cytoplasm.