PharMolix/UniProtQA huggingface dataset:
Protein: MGTE_THET8
Sequence: MEEKLAVSLQEALQEGDTRALREVLEEIHPQDLLALWDELKGEHRYVVLTLLPKAKAAEVLSHLSPEEQAEYLKTLPPWRLREILEELSLDDLADALQAVRKEDPAYFQRLKDLLDPRTRAEVEALARYEEDEAGGLMTPEYVAVREGMTVEEVLRFLRRAAPDAETIYYIYVVDEKGRLKGVLSLRDLIVADPRTRVAEIMNPKVVYVRTDTDQEEVARLMADYDFTVLPVVDEEGRLVGIVTVDDVLDVLEAEATEDIHKLGAVDVPDLVYSEAGPVALWLARVRWLVILILTGMVTSSILQGFESVLEAVTALAFYVPVLLGTGGNTGNQSATLIIRALATRDLDLRDWRRVFLKEMGVGLLLGLTLSFLLVGKVYWDGHPLLLPVVGVSLVLIVFFANLVGAMLPFLLRRLGVDPALVSNPLVATLSDVTGLLIYLSVARLLLEAV
What is the function of this protein?
Highly selective magnesium channel that plays an important role in Mg(2+) homeostasis (PubMed:17700703, PubMed:19798051, PubMed:25367295, PubMed:33905418).  Functions as a Mg(2+)-dependent gating channel (PubMed:19798051, PubMed:25367295, PubMed:33905418).  Exhibits low activity with cobalt, suggesting that it might also be involved in the uptake of Co(2+) as a micronutrient (PubMed:19798051).  Also exhibits low activity with Ca(2+), but it shows almost no activity with Mn(2+) (PubMed:25367295).
What are the official names of this protein?
Magnesium transporter MgtE.
What is the protein family that this protein belongs to?
Belongs to the SLC41A transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KU70_DICDI
Sequence: MSGTNSWLNNNNNNSNTTLTNTNTIGGTNFGINQFDGDDWDNIFDGNNGDGDGDLDGDSYKSYQNPYSYRDCIIFLIDASKAMFEPNENNEIPFHNAVKCLIQTITDKIITSDSDLIGVCFYNTNKKKNINDFENIYVLSDLDIPDPKIILTLEEMLENSNFTTNGLGNCQGEMPFCDALWTCSTMFSNIKQSGSSSGENSNNNNFKRIFLFTNEDNPNAYNDSIRNSSIQRSKDLSDLNIQIELFSMNKSVNDKFDFSLFYQHILIFADEENYLDPTQFDASSKFSDLRFKLKRKEFKKRSLGKLPLYIGNLNNNNNNSNSLDSQVIISTQLYNLFSHAHKSSPTLLDPKTNLPVKQLIKNVCANTQATLLPSQIKLCYHYGGEPVIFTKDEMQTIKSIDRIGFTLLGFKPLENIKPYHSIKHSQFIFPDDQSIKGSVLAFNALVEQMLKSGKAAICRFTPRSSSSPRMVALIPQEEILQSESEFNNQQLLNSLSSQQQQQQSSQQSSSSQQQQQQQQQQQQQQQQQQQQQLPSSSQQSNNNRKIQIRPRGMHVIYLPFADDIRYPNNIGVKSDGLEIKQENIDKAKNIIKMMKIKFDEKKFVNPGLQKHYASLQAIALERDKVEETVDNIQPDRKLIEKVIDTTQDFSDGIFPVGYASTVSSATSSTSSSSAKRLRDGKDLSTMDWPDMVKSGEIIKLTVDDLKSFLSNQNIKPSSKAKKADLIDLISNLISGGNFKPDKLHLLKKDSPPLSDNTITTNGGDDDDNNRPSKKVKSTSTSTTASKNTSSSSPPLVSAATMNKKAPPKKSFSVKDKNSSNNSSGGSSKANVNDEFDIDFKNSDQDDDTDNESDVNNKATTSTTTITTTTAAPKKNNFVNNGMFDTRELCKYGKNCYRTNKQHLDEYRHQ
What is the function of this protein?
Involved in non-homologous end joining (NHEJ) DNA double strand break repair.
What are the official names of this protein?
ATP-dependent DNA helicase ku70.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYFB_STRA5
Sequence: MLVSYKWLKELVDVDVTTAELAEKMSTTGIEVEGVETPAEGLSKLVVGHIVSCEDVPDTHLHLCQVDTGDDELRQVVCGAPNVKTGINVIVAVPGARIADNYKIKKGKIRGMESLGMICSLQELGLSESIIPKEFSDGIQILPEGAIPGDSIFSYLDLDDEIIELSITPNRADALSMRGVAHEVAAIYGKKVHFEEKNLIEEAERAADKISVVIESDKVLSYSARIVKNVTVAPSPQWLQNKLMNAGIRPINNVVDVTNYVLLTYGQPMHAFDFDKFDGTTIVARNAENGEKLITLDGEERDLIADDLVIAVNDQPVALAGVMGGQSTEIGSSSKTVVLEAAVFNGTSIRKTSGRLNLRSESSSRFEKGINYDTVSEAMDFAAAMLQELAGGQVLSGQVTEGVLPTEPVEVSTTLGYVNTRLGTELTYTDIEEVFEKLGFAISGSEVKFTVLVPRRRWDIAIQADLVEEIARIYGYEKLPTTLPEAGATAGELTSMQRLRRRVRTVAEGAGLSEIITYALTTPEKAVQFSTQATNITELMWPMTVDRSALRQNVVSGMLDTIAYNVARKNSNLAVYEIGKVFEQTGNPKEDLPTEVETFTFALTGLVEEKDFQTKSKPVDFFYAKGIVEALFIKLKLDVTFVAQKGLASMHPGRTATILLDGKEIGFVGQVHPQTAKQYDIPETYVAEINLSTIESQMNQALIFEDITKYPSVSRDIALLLAESVSHHDIVSAIETSGVKRLTAIKLFDVYAGNNIAEGYKSMAYSLTFQNPNDNLTDEEVAKYMEKITKSLVEKVNAEIR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFAP_PSEAE
Sequence: MRLVLEEPFKRLWNGRDPFEAVEALQGKVYRELEGRRTLRTEVDGRGYFVKIHRGIGWGEIAKNLLTAKLPVLGARQEWQAIRRLHEAGVATMTAVAYGERGSDPARQHSFIVTEELAPTVDLEVFSQDWRERPPPPRLKRALVEAVARMVGDMHRAGVNHRDCYICHFLLHTDKPVSADDFRLSVIDLHRAQTRDATPKRWRNKDLAALYFSALDIGLTRRDKLRFLRTYFRRPLREILRDEAGLLAWMERKAEKLYERKQRYGDLL
What is the function of this protein?
Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.  The phosphorylation of the lipopolysaccharide core seems to occur prior to translocation to the periplasm and attachment of O-antigen.  Also has protein-tyrosine kinase activity: autophosphorylates on all Tyr residues; in vitro can phosphorylate poly(Glu,Tyr).
What are the official names of this protein?
Lipopolysaccharide core heptose(I) kinase RfaP, Lipopolysaccharide kinase WaaP.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_THIDA
Sequence: MPVSLLRALLVFSLLCLGLSATRAAHAAMEIEVVGGAANKIAIAMVPFQTAAGQPSPPLTQIVADDLARSGQFSMTDVTGAAQPVEPSQVDYAAWRTKGAEAMVIGQVVALGGGRFEVRFRLLDVVKGTQLAGYSYKITAAQWRATGHRIADVVYEKLTGIPGAFSSRIAYVQKQGKRYELRVADADGQNPRTIVRSLEPLISPMFSPDGTRLAYVSFEDKKPVVYVQSLQQGGRRKVAAFKGSNSAPAWSPDGRQLAVVLTRDGASQIYLINVDGSGLTRLMRSGDIDTEPVFSPDGQTLYFTSDRGGSPQIYRVAKSGGDAKRVSFEGSYNVSPTISPDGRYLAYISRDGGRFRVVLQELASGQTRVLTETTRDEAPSFAPNGQAVLYATVQGGRGVLGTVTLDGKTRARLSESGVDAREPAWGP
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MON1_ORYSJ
Sequence: MDMDPPTNNPSPPGPPDSPPPEKRLASLSLRTSHLPPDFEIHDDYDDDDDEGYLTAVSRVGSISTSASAWKDDLEDADVAPPSPSSSGYAAERGTSLASSAAANDDPQPQPDDDDWPRDKKHLHEDDTSASWRKRKKHFFILSNSGKPIYSRYGDEHKLAGFSATLQAIISFVENSGDHIKFVRAAKHQIVFLVKGPIYLVCISCTEESYEGLRGQLELMYGQMLLILTKSVNRCFEKNPKFDMAPLLGGTDAVFLSLIHAFSWNPATFLHAYTCLPLAQSTRQAASAVLQDIADSGVLFALLMCEHKVISLVGAQKATLHPDDIFLLSNFILSSESFRTSESFSPICLPRYNSMAFLYAYVHFFDENTYLTLLTARSDAFYDLKDSRSRIQNVLLKANVLVEVQRSLRESALRIEDLPADPSSQSVSPPPQFSQDLHFQLLSSEMAIGGPAGLWHFIYKSIYLDQYVSSEFPLIISNPKQQKRLYKAYQKLYASMHDKATGPHKTQFRRDEDYVLFCWITQDFELYAAFNPLADKSQAIKVCNRVCQWIRDLENEIFVYGESTLSW
What is the function of this protein?
Plays an important role in membrane trafficking through the secretory apparatus.  In complex with CCZ1, acts as a guanine exchange factor (GEF) for Rab7 protein family.  Promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form.  The active form is involved in protein trafficking from prevacuolar compartments (PVCs) to vacuoles.  May serve as a linker between Rab5 and Rab7 protein families in PVCs and mediate PVC maturation.
What are the official names of this protein?
Vacuolar fusion protein MON1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MON1/SAND family.
What are the subcellular locations of this protein?
Endosome. Prevacuolar compartment.
Protein: 123R_IIV6
Sequence: MEPTKIVENLYLGNIQNGIRHSNYGFDKIINLTRFNNQYGIPTVWINIDDSESSDLYSHLQKVTTLIHDSIENGNKVLVHCQAGISRSATVVIAYIMRSKRYSLQDAFNFVKKKRSIIFPNAGFIKQLAQFERWLNSTNSYF
What are the official names of this protein?
Putative tyrosine phosphatase 123R.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: LYPL1_HUMAN
Sequence: MAAASGSVLQRCIVSPAGRHSASLIFLHGSGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRILIGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTTKFHSFPNVYHELSKTELDILKLWILTKLPGEMEKQK
What is the function of this protein?
Has depalmitoylating activity toward KCNMA1.  Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site.
What are the official names of this protein?
Lysophospholipase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytosol.
Protein: CYSK_WHEAT
Sequence: MGEASSPAIAKDVTELIGNTPLVYLNKVTDGCVGRVAAKLESMEPCSSVKDRIGYSMITDAEEKGFIVPGKSVLIEPTSGNTGIGLAFMAAAKGYRLVLTMPASMSMERRIILKAFGAELILTDPLLGMKGAVQKAEELAAKTPNSYILQQFENAANPKIHYETTGPEIWKGTGGKIDGLVSGIGTGGTITGTGKYLQEQNPNIKLYGVEPTESAILNGGKPGPHKIQGIGAGFIPGVLDVDIIDETIQVSSDESIEMAKSLALKEGLLVGISSGAAAAAAIKVAQRPENAGKLFVVVFPSFGERYLSSVLFHSIKKEAESMVVE
What are the official names of this protein?
Cysteine synthase, CSase A, O-acetylserine (thiol)-lyase, OAS-TL A, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_BURO0
Sequence: MSDTEYLARAEAVLAAVERTVDVANDGDHDIDLERNGSVLTLTFENGSKIIVNLQPPMKEVWIAAKAGGFHYRFIDGEWRDTRTGTEFFSALTEYATQQAGLPITFSA
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: RL21_MARN8
Sequence: MYAVIVSGGKQHRVKEGETLKLEKLEVETGGSVEFDRVLLVANGDDVKVGAPVVEGAKVTAEVVSHGRHDKVNIIKFRRRKHHMKRQGHRQWFTEVKITGIQG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: UREE_HELAH
Sequence: MIIERLTGNLRDLNPLDFKVDYVDLEWFETRKKIARFKTRQGKDIAIRLKDAPKLGLSQGDILFKEEKEIIAINILDSEVIHIQAKSVAEVAKICYEIGNRHATLYYGESQFEFKTPFEKPTLALLEKLGVQNRVLSSKLDSKERLTVSMPHNEPNFKVSLASDFKVVMK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX108_LYCSI
Sequence: MMKVLVVVALLVTHISYSSSEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1b, Toxin-like structure LSTX-A8.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LUXS_STAAE
Sequence: MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: ACKA_NITHX
Sequence: MDSILVVNAGSSSVKFQVFSAEGEGKLLRQIKGQVDGIGSRPRLRASGADNEPLADRAYPIESVSDVPAAMGVAGGWLRDELRISPMAVGHRVVHGGPDYDRPVLIDHGVVARLERFVALAPLHQPNNLDPIRSLLANFPALPQVACFDTAFHRTHDAVADYYAIPYQFYVEGVRRYGFHGLSYEYVAKTLPHVAPEIAKGRVIVAHLGSGASMCALKGGRSIESTMGFTALDGLPMGTRPGQIDPGVVLYLVSEKGMSPAKAQDFLYRDCGLKGLSGVSNDMRELEASEDPKAKLAVDYFVYRVGLNAGMLAAALQGLDAFVFTAGIGENSMRIRARIADQLAWLGVTLDPTQNSRHARLISGSDSRIPVYVIPTDEELMIAQHTLSLLLDRSSSSVRHERVS
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_PEDPA
Sequence: MAEQVTSAQATAKTVRIAARKIRLVVDLIRGKSVAEAFAILKFTPRSASPVVEKVLKSAVANAENNFDLDREDLVISKVFVNEGPTLKRFRPRAKGSASPINKRTSHITVVVSEKQEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SHH_TANAL
Sequence: YGRRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTVMNQWPGVKLRVTEGWDEDGHHFEESLHYEGRAVDITTSDRDNSKYGTLSRLAVEAGF
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.  Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes.  Displays floor plate-inducing activity.  Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes.  In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).
What are the official names of this protein?
Sonic hedgehog protein, SHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Sonic hedgehog protein C-product: Secreted, extracellular space. Sonic hedgehog protein N-product: Cell membrane; Lipid-anchor. The C-terminal peptide diffuses from the cell, while the N-product either remains associated with lipid rafts at the cell surface, or forms freely diffusible active multimers with its hydrophobic lipid-modified N- and C-termini buried inside.
Protein: PSIE_LISIN
Sequence: MKRLEKISSIVPILLRITLNLALIMVGFTLVAFLIREAFTIFNNIFFLDTDVSYYYMTQDILTFFLYFEFIALIVKYFESHFHFPLRYFIYIGITAIIRFIIVDHSSATSTLILSGAILLLVAALFLANTKLLKREG
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SMG7_MOUSE
Sequence: MSLQSAQYLRQAEVLKAEMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHSSTIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDELKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHSYSQDEQLCWTQLLALFMSFLGILCKCPLQNDSQESNNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPREDDLSNTNATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVVESLATDGSPGLKSVLSTGRNPSNSCDSGEKPVVTFKENIKPREVNQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPSQTSNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQSTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQPPLTSLPAQPTAQSTSQLQVQALAQQQQSPTKVIPALGKSPPHHSGFQQYQQADASKQLWNPPQVQSPLGKIMPVKQSYYLQTQDPIKLFEPSLQPPVIQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRAVMAQQPNMDRRSKRSPGVFRPEQDPVPRMPFEDPKSSPLLPPDLLKSLAALEEEEELIFSNPPDLYPALLGPLASLPGRSLFKSLLEKPSELMSHSSSFLSLTGFSVNQERYPNSSMFNEVYGKNLTTSSKAELNPSVASQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSAPFSNFGPIGTPDNRDRRPADRWKTDKPAMGGFGVDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGAMNPPH
What is the function of this protein?
Plays a role in nonsense-mediated mRNA decay.  Recruits UPF1 to cytoplasmic mRNA decay bodies.  Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG7, SMG-7 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, and nuclear. Shuttles between nucleus and cytoplasm.
Protein: KDSA_MARN8
Sequence: MARSNLNVSGIEIANDRPFVLFGGMNVLESRELAFEVAEKYVDVCTRLGIPYVFKASFDKANRSSVNSFRGPGLEKGLQILADIKSKFGVPIISDVHEPGQAAPAAEVCDIIQLPAFLSRQTDLVVAMAKTGAVINIKKAQFLAPQEMKHIITKCEEAGNDQIILCERGTSFGYNNLVVDMLGFGIMKQMNVPVFFDVTHALQMPGGRADSAGGRRAQVTDLALAGMSQGLAGLFLEAHPDPDKARCDGPCALRLSQLEPFLERVKAVDDLVKSFKPIDTA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABDH_SHISS
Sequence: MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAAVRAADAAFAEWGQTTPKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINILFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHAASSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVSKAVEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNEEQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVKH
What is the function of this protein?
Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA).  This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal.  Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Gamma-aminobutyraldehyde dehydrogenase, ABALDH, 1-pyrroline dehydrogenase, 4-aminobutanal dehydrogenase, 5-aminopentanal dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
Protein: KHSE_BACC1
Sequence: MIPLSIRVPASTANVGPGFDSVGIALSLYLHVVVKEKSNKWQVIHSFDESIPTDDKNLIVSTACKVSPSLSPYIIEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTTDQKVQIATNFEGHPDNVAASILGGTVIGALDGKNVSVVRIESKELGVISLIPNEELNTDESRSVLPDVFPFHEAVKASAISNVLVAALCQKKWEVVGEMMERDHFHEPYRLELVPLLPSIRKCAKEFGAYGTALSGAGPSIFILTPYEKRQEIAEQLARVFTSMKVCELEIDHTGITVNKEERIEL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTE_ECO24
Sequence: MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQGALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDMNRMFGGRWQLFAESGETCRARELEQCLEDFYDLGKESVRWHLDLHTAIRGSLHPQFGVLPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFGQNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFMPFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: U63A_CONCL
Sequence: MRFLHFLIVAVLLASFMESGAMPRNPKKKRGWDTPAPCRYCQWNGPQCCVYYCSSCNYEEAREEGHYVSSHLLERQGR
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal6.3a.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGI_ALISL
Sequence: MTNRWSFDVKKNLVTLILTWLCLSISTAQAARIKDVSEVAGVRSNQLIGYGLVSGLPGTGESTPFTDQSFNAMLQNFGIQLPPGTKPKTKNVAAVMVTTTLPAFAKQGQVVDITVSSVGSAKSLRGGTLLQTFLKGLDGKTYAIAQGNLIVSGFSATGADGSKIVGNNPTVGRISGGAMVEREVPSPFGRGDFITFNLLDSDFTTAQRMADAVNNFLGPNMASAVDATSVRVRAPRDISQRVAFLSAVENVNFDPADGSAKIIVNSRTGTIVVGKHVRLRAAAVTHGGMTVAIKENQQVSQPGPFGNGKTVVTQDSDIEVTEKQGKMFKFEPGLTLDDLVRAVNEVGAAPSDLMAILQALKQAGAIEGQLIII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: RS15_LIMRJ
Sequence: MAISKERKDQIIKEFATHEGDTGSTQVQVAVLTADINELNDHLRTHKHDYHSQRGLMKKIGHRRNLLAYLRRTDLPAYRELIQKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TX23B_AGEAP
Sequence: MKLCMTLLITAIAVVTFVVATQEESAEFNEVEESREDNCIAEDYGKCTWGGTKCCRGRPCRCSMIGTNCECTPRLIMEGLSFA
What is the function of this protein?
Antagonist of voltage-gated Cav2. 1/CACNA1A (P-type) calcium channels.  Paralyzes insect by blocking neuromuscular transmission.
What are the official names of this protein?
Omega-agatoxin-Aa4b, Omega-AGTX-Aa4b, Omega-agatoxin IVB, Omega-Aga-IVB, Omega-agatoxin IVC, Omega-Aga-IVC, Omega-agatoxin tsukuba, Omega-Aga-TK, Omega-agatoxin-TK, Omega-agatoxin-4B.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family. 03 (omega-agtx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CS_CATRO
Sequence: MNSSTDPTSDETIWDLSPYIKIFKDGRVERLHNSPYVPPSLNDPETGVSWKDVPISSQVSARVYIPKISDHEKLPIFVYVHGAGFCLESAFRSFFHTFVKHFVAETKVIGVSIEYRLAPEHLLPAAYEDCWEALQWVASHVGLDNSGLKTAIDKDPWIINYGDFDRLYLAGDSPGANIVHNTLIRAGKEKLKGGVKILGAILYYPYFIIPTSTKLSDDFEYNYTCYWKLAYPNAPGGMNNPMINPIAENAPDLAGYGCSRLLVTLVSMISTTPDETKDINAVYIEALEKSGWKGELEVADFDADYFELFTLETEMGKNMFRRLASFIKHE
What is the function of this protein?
Component of iboga and aspidosperma monoterpenoid indole alkaloids (MIAs, e. g.  tabersonine and catharanthine) biosynthesis pathway from 19E-geissoschizine.  Catalyzes the conversion of O-acetylstemmadenine (OAS) to catharanthine.
What are the official names of this protein?
Catharanthine synthase, Hydrolase 1, CrHL1.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: CV039_HUMAN
Sequence: MCRCSLVLLSVDHEVPFSSFFIGWRTEGRAWRAGRPDMADGSGWQPPRPCEAYRAEWKLCRSARHFLHHYYVHGERPACEQWQRDLASCRDWEERRNAEAQQSLCESERARVRAARKHILVWAPRQSPPPDWHLPLPQEKDE
What are the official names of this protein?
UPF0545 protein C22orf39.
What is the protein family that this protein belongs to?
Belongs to the UPF0545 family.
Protein: DOF15_ARATH
Sequence: MATQDSQGIKLFGKTITFNANITQTIKKEEQQQQQQPELQATTAVRSPSSDLTAEKRPDKIIPCPRCKSMETKFCYFNNYNVNQPRHFCKGCQRYWTAGGALRNVPVGAGRRKSKPPGRVGGFAELLGAATGAVDQVELDALLVEEWRAATASHGGFRHDFPVKRLRCYTDGQSC
What is the function of this protein?
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.  Acts as a negative regulator in the phytochrome-mediated light responses.  Controls phyB-mediated end-of-day response and the phyA-mediated anthocyanin accumulation.  Not involved in direct flowering time regulation.
What are the official names of this protein?
Dof zinc finger protein DOF1.5, AtDOF1.5.
What are the subcellular locations of this protein?
Nucleus.