PharMolix/UniProtQA huggingface dataset:
Protein: P53_RAT
Sequence: MEDSQSDMSIELPLSQETFSCLWKLLPPDDILPTTATGSPNSMEDLFLPQDVAELLEGPEEALQVSAPAAQEPGTEAPAPVAPASATPWPLSSSVPSQKTYQGNYGFHLGFLQSGTAKSVMCTYSISLNKLFCQLAKTCPVQLWVTSTPPPGTRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNPYAEYLDDRQTFRHSVVVPYEPPEVGSDYTTIHYKYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKKEEHCPELPPGSAKRALPTSTSSSPQQKKKPLDGEYFTLKIRGRERFEMFRELNEALELKDARAAEESGDSRAHSSYPKTKKGQSTSRHKKPMIKKVGPDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.  Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity).  However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity).  In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.  Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression.  Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1.  LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation.  Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2.
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Interaction with BANP promotes nuclear localization. Recruited into PML bodies together with CHEK2. Translocates to mitochondria upon oxidative stress. Translocates to mitochondria in response to mitomycin C treatment (By similarity).
Protein: ERO1A_HUMAN
Sequence: MGRGWGFLFGLLGAVWLLSSGHGEEQPPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKYSEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDENSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH
What is the function of this protein?
Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum.  Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation.  Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell.  Required for the proper folding of immunoglobulins (PubMed:29858230).  Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.  Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V. cholerae, thereby playing a role in retrotranslocation of the toxin.
What are the official names of this protein?
ERO1-like protein alpha, ERO1-L, ERO1-L-alpha, Endoplasmic oxidoreductin-1-like protein, Endoplasmic reticulum oxidoreductase alpha, Oxidoreductin-1-L-alpha.
What is the protein family that this protein belongs to?
Belongs to the EROs family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Golgi apparatus lumen. Secreted. Cell projection, dendrite. Note=The association with ERP44 is essential for its retention in the endoplasmic reticulum (PubMed:29858230). In neurons, it localizes to dendrites (By similarity).
Protein: MGSA_EXIS2
Sequence: MNIALIAHDEKKDEMMMFTRAYEAYFAKNTLYATGTTGQRIMEATALTVHRCKSGPLGGDQEIGAMVARGEIDIVIFLRDPLTAQPHEPDVSALIRLCDVYDLPLATNVGTAEILINGLEQGEFQWREIIRKRHEEEQRKFLTD
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: GATC_ORITI
Sequence: MISINEVQSIANYCKLRFNEQELNHMVKQLSSIVEMMNKLEKIDCTSVPPMRHFEENNRMRKDQVEQNITVDQLLSNVPQSSATIAKNTKYFVVPKIIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CYCA_ECO57
Sequence: MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPDLSDWVASLAVIVLLLTLNLATVKMFGEMEFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVFVVVLLTLEDDTRQALLVTPLWFIALGLGWLFIGKKRAAELRK
What is the function of this protein?
Permease that is involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine.
What are the official names of this protein?
D-serine/D-alanine/glycine transporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPH_CAUVC
Sequence: MSTLHDLNGATIAFDLDGTLVDTAPDLVGALNIILAQESLPPLPFDDVRLMVGRGARALLERGFAAAGAPLDAEQAPALVQRFIDVYLARIADESAPFPGVVEVLSDLKTAGAKLVVCTNKLTNLSTALLDAVALSPFFEAVIGADLAPAAKPDGRHVAAAVAAVGGDVSRAVMIGDSVNDALGARNAGVPGVLVSFGYTEEPVETLGADLVIHSFLDVPKACITLLTSCPAPNTGL
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: HLYB_ECO57
Sequence: MMSKCSSHNSLYALILLAQYHNITVNAETIRHQYNTHTQDFGVTEWLLAAKSIGLKAKYVEKHFSRLSIISLPALIWRDDGKHYILSRITKDSSRYLVYDPEQHQSLTFSRDEFEKLYQGKVILVTSRATVVGELAKFDFSWFIPSVVKYRRILLEVLTVSAFIQFLALITPLFFQVVMDKVLVHRGFSTLNIITIAFIIVILFEVILTGARTYIFSHTTSRIDVELGAKLFRHLLALPVSYFENRRVGETVARVRELEQIRNFLTGQALTSVLDLFFSVIFFCVMWYYSPQLTLVILLSLPCYVIWSLFISPLLRRRLDDKFLRNAENQAFLVETVTAINTIKSMAVSPQMIATWDKQLAGYVASSFRVNLVAMTGQQGIQLIQKSVMVISLWMGAHLVISGEISIGQLIAFNMLAGQVIAPVIRLAHLWQDFQQVGISVERLGDVLNTPVEKKSGRNILPEIQGDIEFKNVRFRYSSDGNVILNNINLYISKGDVIGIVGRSGSGKSTLTKLLQRFYIPETGQILIDGHDLSLADPEWLRRQIGVVLQENILLNRSIIDNITLASPAVSMEQAIEAARLAGAHDFIRELKEGYNTIVGEQGVGLSGGQRQRIAIARALVTNPRILIFDEATSALDYESENIIMKNMSRICKNRTVIIIAHRLSTVKNANRIIVMDNGFISEDGTHKELISKKDSLYAYLYQLQA
What is the function of this protein?
Part of the ABC transporter complex HlyBD involved in hemolysin export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Alpha-hemolysin translocation ATP-binding protein HlyB, EHEC-HlyB protein.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIVB4_BRUA2
Sequence: MSLKVFLQAGVACAALSLAGAAGASAEPLKIALVETLSGPQASTGLLYRAAVLYQLGKINEAGGFNGEKIQILEYDNQGGPVGAADRVKAAIADGAQIIVQGSSSAVAGQITEDVRKYNLRNKGKEVLYLNLGAEALELTGSKCHFYHFRFSPNAAIRFKTVAQGMKDKGILGERAYSINQNYSWGVDVENTVVANAKEIGYEVVDKTLHEVNKIQDFSPYVAKIQAANVDTVFTGNWSNDLLLLMKAASGAGLKAKFATSFLDQPGNIGNAGAIAEGHIVSTPFNPEANGEASMAFAEDYKKVTGHYPSYVEPAAVFGLQLFGEALKNVKPGEGKINTTDIALAIENASVKTPMGDYSMRSDDHQAKFPMVVQEVSKKARIKADGTEYGFLPFKTFTGDESIDPVQESCSMKRPG
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 4.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
Protein: RS17_RICTY
Sequence: MRNIKMPKRVLQGVVISSKTDKTVTVKVERKFKHPIYKKFVKVSKKYAAHDIENKYREGDKVSIVESRPISKTKTWVVVNVE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: KAPCG_HUMAN
Sequence: MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
What is the function of this protein?
Phosphorylates a large number of substrates in the cytoplasm and the nucleus.
What are the official names of this protein?
cAMP-dependent protein kinase catalytic subunit gamma, PKA C-gamma.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Protein: RBFA_ACET2
Sequence: MERIERISEEIKREISDIIQNELKDPRLSKLISITEVNVTKDLRYAKVYVSVMGSEEEKANSLEGLKSAAGFIRREIGRRVQLRYTPEIHFELDNSIERGAYITKLINETSAQNKGSKDPEDT
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPED_STRM5
Sequence: MVKPLPRLRLQGFNNLTKALSFNIYDVCYARTEEERQRYIEYIDEEYNADRLTQILTDVAEIIGANILNVARQDYDPQGASVTILISEEPVIDKKQAGKELISDAVVAHMDKSHITVHTYPETHPQEGIATFRADIDVATCGVISPLKALNYLIESLESDIVIMDYRVRGFTRDVKGKKHYIDHKINSIQNFLAKNIKSRYEMFDVNVYQENIFHTKMHLKDFDLDQYLFEEKAKNLSFKERMKIEALLKREIEELFHGRNLSE
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: NUOI1_KORVE
Sequence: MSIAPLLRKVFLIDLIKGLSITFKYQAPKDCQTEQYPQERPVITDRFRGQPMMKLGENGETLCIGCNLCALACPENLIAMKSDRDPVTKKKVMVTYVYDVSRCMFCGLCEEACPTQSLKLGTGYEMALYSREGMVLDRKVLEHRTAPEPYEK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 1, NADH dehydrogenase I subunit I 1, NDH-1 subunit I 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ANLN_XENLA
Sequence: MDPFTEKLLERTRARRENLQKKMADRPTAGTRTAALNKRPREPLLEANHQPPAPAEEAKPSSKPSPSKRRCSDNASTPDAGAENKQPKTPELPKTELSAVASHQQLRATNQTPQVSLLSSDKELTASDVKDASSVKTRMQKLADQRRYWDNNVSPSSSPPAHVPPKDIIVSPPKPQIPDVGNDTPVGRRGRFANLAATIGSWEDDLSHPFVKPNNKQEKPGTACLSKESTTSSASASMNSHSVKQDTTSCSQRPKDTTVNKAVCSGQLKNILPASKPASSVASTEVSGKSKPLAIKSPAVVTSKPNENVLPASSSLKPVSANSSPQKTERPASRIYSYQSASARNELNNNTPVQTQQKDKVATSGGVGIKSFLERFGEKCQEHSPAPLNQGHRTAVLTPNTKSIQERLLKQNDISSTASLAQQQKKEREKELAALRGRYDRRNVWTKQEDEQQGTFPETSSNLPTSDVASCSETKRAEASGITSEKSVSGHFHPNMAEQVSSPEKIPTPVQSQLPLESPRLVNEGNTGNVACEVEMSVDGSIEEINSSGIITNIFSDVLEQHDEEGEEVDECLVEQVETDTDDEEREDEEEDALNISSMSLLAPLAETVGIESPKALLSPSNKVAAGNGESCDRKRSGRFQKSHVLRAESNDGIGSSEENQNLLYSIDAYRSQRFKETDRPPIMQTIVRKEDVSSRLQDKKTASPLSVNIKQKMKTLSNEVNLQQTVIHQASQALNCCIDEDHGKGSETEAEAERLLIVATEKRAALIAELNKIKNEGPQSQKKNVSNESAPSRGCISVSEMFLPLKADFVCNATQRMDSANYYFFLMIRAGAENIVASPLTSITSTMKGDALAFPTTFSLEDVSNDFEICVEVYSLVQKKEGHAPDKKKKTMKSKAITPKRLLTSITKSNMHTPALASPGGPNAVRTSNFVLVGSHKLTLSSIGSNKFPLDKVPFLSPLEGHIYLKIKCHVNSSVEDKGFLTMFEDVSGFGAWHRRWCVLSGYCISYWTYPDDEKRKKPIGRINLANCTSRKIEPANREFCARPNTFELITVRPQREGDRETLVSQCRDTLCVTKNWLSADTKEERNLWMQKLNQFLVDLRMWQPNACYRPASKP
What is the function of this protein?
Required for cytokinesis.  Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression (PubMed:12479805).  Plays a role in bleb assembly during metaphase and anaphase of mitosis.  May play a significant role in podocyte cell migration (By similarity).
What are the official names of this protein?
Anillin.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cell projection, bleb. Note=Mainly found in the nucleus during interphase. Colocalizes with cortical F-actin upon nuclear envelope breakdown in mitosis and subsequently concentrates in the area of the prospective contractile ring in anaphase.
Protein: UPP_MARSD
Sequence: MAVHVVDHPLVRHKLGILREDGISTSRFRALAQEISRLLTYEATKDLATEAKTITGWAGEVEVEEIKGKKITVVPILRAGLGMMDGVLDMVPGARVSVVGFYRDEETLQPVEYYVKLASNIDERIALILDPMLATGGTLMATIDLLKKSGCTNIKGLFLVAAPEGIEKIVKAHPDVDIYTASIDEKLNDAGYILPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RSMG_LISMC
Sequence: MNPEQFQTALAEKGIELSDTQLKQFHDYFEMLVEWNEKMNLTAITDEKEVYLKHFYDSISAAFYVDFTKFDTICDVGAGAGFPSLPIKICFPHLKVSIVDSLKKRMTFLDALAEKLGLTDVHFYHDRAETFGQNKAHREKYDLVTARAVARMSVLSELCMPLVKKGGSFLVMKAAQAEQELQTAEKAIKLFGGKVEEHFAFSLPVEESERNIYVITKTKETPNKYPRKPGTPNKLPIE
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP6B_SULIM
Sequence: MSAKEKFTSLSPAEFFKRNPELAGFPNPARALYQTVRELIENSLDATDVHGILPNIKITIDLIDEARQIYKVNVVDNGIGIPPQEVPNAFGRVLYSSKYVNRQTRGMYGLGVKAAVLYSQMHQDKPIEIETSPANSKRIYTFKLKIDINKNEPIIVERGSVENTRGFHGTSVAISIPGDWPKAKSRIYEYIKRTYIITPYAEFIFKDPEGNVTYYPRLTNKIPKPPQEVKPHPYGVDREEIKILINNLKRDYTIKEFLVNEFQSIGDTTADKILELAGLKPNKKVKNLTEEEITRLVETFKKYEDFRSPSADSLSVIGEDLIELGLKKIFNPDFAASITRKPKAYQGHPFIVEAGVAFGGSIPVGEEPIVLRYANKIPLIYDEKSDVIWKVVEELDWKRYGIESDQYQMVVMVHLCSTKIPYKSAGKESIAEVEDIEKEIKNALMEVARKLKQYLSEKRKEQEAKKKLLAYLKYIPEVSRSLATFLASGNKELVSKYQNEISEGLFKLISKKLDLINIEEYRKVYRVDSE
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: PRMA_STAAM
Sequence: MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPEDKYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNIQFSEQIIAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTTSMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIKEKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNRE_LEGPA
Sequence: MDYYFTKGKPQLVNMKTPIYLVTQFQQLMDLMQNQYEVSCLELMQRSGKAACDFLVYRWPKVKKISIFCGRGDNGGQGYVLAQQAKKMGMIPTVWQVGHQMSMSKPPQMHKEVWYEMNSCHQQGIVLHTYSPDIDLGDPELIVDALFGVGLYGHVRPEIALLLQRLQQFTVPILAIEVPTGINASTGEIAGNALAATATITFLCMKLGLLINDGKIYSGEIAFDDLLAPEEIYQQVKGIEESSLLDSSTCFSKKIWYRNKTQKGWQLSIN
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: SC23G_ARATH
Sequence: MDFLELEAIEGLRWSWNSWPTTKSDCESLVVPLSIMYTPLMHFSELPTIPYDPLICSRCGAVLNPYARVDYQSRIWSCPFCFHKNLFPRSYSGITETNLPAELFPTYSAVEYSPLPSRQSGSNTTTPTAAASWSNGFNQGVRSMPSNSSFSSLASSTVGGGGGVISELGPAFVFVVDASMVEDELRAVRSDVLFVIEQLPENCLVALITFDSMVRVYDLGFSECSKVVVFHGERDLSPDQIQQFLGLGYSKQFHHGKMSAIRKQSFLLPLVECEFNLTSAFEEIIPLVDVKPGHRPHRSTGAAISTALGLLEGCSVTTGSRIMVFTSGPATRGPGIIVDSDLSNSIRTHRDIITGHVSYYDKSCGFYKKLAKRLCDSSVVLDVFACSLDQVGAAELRYAVEMSGGFLLLGETFESEQFKKCLRHIFIRDADGNLSMYFDVSLEVVTTKDMRICGALGPVVSLRQKNDIVSETEIGEGGTYMWKTSTVTNKTCVSFFFHVSNEQNRKPQPGSAFFIQFITRYRYGNGAMRKRVTTVARRWVAGKSPEISSSFDQETAASVMARLAINRAEECHARDVITWLDNGLIRFASRFGDYIQEDPSSFRLTPNFSLYPQFMFYLRRSQFLDVFNNSPDETGFFRLMLNREGVVNSIIMIQPTLLRYSFDGPPVPVLLDIRSVTPDVILLFDSYFYVVIHHGSKIAQWRKLEYHKDPSHETFRNLLEAPEIDAAQLVTDRIPMPRIVRCDQHGSQARFLLAKLNPSVTQKTDHTGGSDIVLTDDMSLQDFLEDLQSLAVKG
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (PubMed:24587212).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (PubMed:24587212).
What are the official names of this protein?
Protein transport protein SEC23 G, AtSEC23G, Protein transport protein SEC23 C, Protein transport protein SEC23 E, AtSEC23E.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
Protein: DLT1_CANGA
Sequence: MILQEQRRLRLWLYKSSLFISVLFLIGFSIVLPVDSIVQAIQSENNGFNTIIVIGSLAVFFVAAVTILIGRMLLHKSCLKDIPRRYIPVTNADLPHKSSRKMVIHNMERSKKLSGLFKTPKDPVIHPGLEPPARCDDPNTPKILPEYLNYKICIKSATDRLKYYGLFLNSASDDVKSSQTFTDLVKSQFIKGNHNKRQVQRAKDFIELYERIRFSGDEVSRSEFIQFAENCIYFSDLMITMDITKVGLGNISTRSQLSFNIAGSSVDRKLRKLNTARSNQISRLSSGQYPDITAFRYDTSNSDYHRQETDEDDFALDDMDYFPSVPPYMIRRNSTNTVSMRIPTSNSDDQYNLGFNEIGDEDIQNNDQIRRYMSNTSKTDSFKTVIHNG
What is the function of this protein?
Required for growth under high-pressure and low-temperature conditions.
What are the official names of this protein?
Defect at low temperature protein 1.
What is the protein family that this protein belongs to?
Belongs to the DLT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LEC3_MEGRO
Sequence: MQRSEIVQAVTLLVVVFAITTAECTCPGNLDWQEYDGHCYWASTYQVRWNDAQLACQTVHPGAYLATIQSQLENAFISETVSNNRLWIGLNDIDLEGHYVWSNGEATDFTYWSSNNPNNWENQDCGVVNYDTVTGQWDDDDCNKNKNFLCKMPIIGCPPCGI
What is the function of this protein?
Sugar-binding protein which recognizes specific carbohydrate structures and agglutinates a variety of animal cells by binding to cell-surface glycoproteins and glycolipids.  Calcium-dependent lectin.  Invertebrate lectins may be involved in defense functions.
What are the official names of this protein?
Lectin BRA-3.
Protein: BBLN_TAEGU
Sequence: MAGPNGDPHVLGGGTGDEGDEGGDTFEEEEYAAINSMLDQINSCLDHLEEKNDHLHICLKELLESNRQTRLEFQQQSKQLNTGADVQGSQPPA
What is the function of this protein?
Essential for intermediate filament organization in intestinal cells, interacts with intermediate filament and regulates intestinal lumen morphology.
What are the official names of this protein?
Bublin coiled-coil protein, UPF0184 protein C9orf16 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0184 (EST00098) family.
Protein: LUKL2_STAAN
Sequence: MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
What are the official names of this protein?
Uncharacterized leukocidin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: YEGU_ECOLI
Sequence: MKTERILGALYGQALGDAMGMPSELWPRSRVKAHFGWIDRFLPGPKENNAACYFNRAEFTDDTSMALCLADALLEREGKIDPDLIGRNILDWALRFDAFNKNVLGPTSKIALNAIRDGKPVAELENNGVTNGAAMRVSPLGCLLPARDVDSFIDDVALASSPTHKSDLAVAGAVVIAWAISRAIDGESWSAIVDSLPSIARHAQQKRITTFSASLAARLEIALKIVRNADGTESASEQLYQVVGAGTSTIESVPCAIALVELAQTDPNRCAVLCANLGGDTDTIGAMATAICGALHGVNAIDPALKAELDAVNQLDFNRYATALAKYRQQREAV
What are the official names of this protein?
Uncharacterized protein YegU.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family.
Protein: MTND_SCHPO
Sequence: MRAYIFQDEGDQRKPNDSKIEVSAEDLEAAKVSYRHHDGDLHTFADGLMKEYGFKNRDEVVVSRKGLGDRYDNMVKKFFEEHLHEDEEIRLILDGNGYFDVRSVDDRWVRIFVEKGDLIILPPGIYHRFTTTTDDYIHAMRLFHENPKWIALSRTDSTSEELDARKSYLNSIKKSVYV
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.