PharMolix/UniProtQA huggingface dataset:
Protein: YR190_MIMIV
Sequence: MEIYADQKYTKLVSHLYYQNSHEIVHSSKIYQLALTNPDILSQYINYPDESNESHESHDCHESQNSTHYKFRLMEIYHKMIIIDNNMDLLDLLFEIMSDDFRCDDCVILDLAIRHQRTDVFNKYIILGFDLNRLINSSTILDEIILWYHQIKKYDTGIELCDYLIDNGASISIHNYCTIINAFDTLNDKYVSFFLNKISLNDLGNLLFWYLRNYYNVNIDIVETILSNGIDINNFHEYSYMLIGKFNVPIMNLFIRYGLIIHDDVIDDACRYGNHLLVDYLMEIGHKPSKQIITNVIENHNVNIIKLFVKYNIDLSDIKPPTSPEIIQLVKSLESNGLSVDYVYGYILDKFNLSGKLCI
What are the official names of this protein?
Putative ankyrin repeat protein R190.
Protein: RISB_SULAC
Sequence: MEMQDQSKINLGIVVSEFNYDITSLMLQRALSHAEFLGVTVKVVVKVPGSYDMAVIVKELLKRDEIDGVVTLGAVIKGETKHDEIVATQTARKLMDLSVEYGKPVTLGIIGHGVTHEQAVERIEEYSMRAVESAVKLIKRLKKLREIDLTKETNVSIE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: KAXU4_MESEU
Sequence: MSRLLIFILTAVVLSVIIDILNNSKVEGQYCCYTCIPDCSKSCQDSGLRFKACIPYRSCLCQY
What is the function of this protein?
May block voltage-gated potassium channels (Kv).
What are the official names of this protein?
Potassium channel toxin MeuTXKalpha4, Potassium channel toxin alpha-KTx, Venom antimicrobial peptide-8.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family.
Protein: IF1C_HUPLU
Sequence: MKKQKLIDMEGVVTESLPNTMFRVCLDNGCQVLTHVSGRMRRNYIRILPGDRVKVESSPYDLTKGRITYRFHTKSSND
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RR3_GRATL
Sequence: MGQKTHPLGFRIGITRDHKSSWFSNMKSYPKLAQEDYKIRSCIEKQLHNASISLIYIDRKVDQVQVHIHTARPGIILGKMGRGLEDLRKKLETTLKNDTQIRINLIEITDPDKEATLIAEFIVQQLEKRIAFRRVIRQAMQRSQKAKNQGIKIQVSGRLNGAEIARSEWVREGRVPLQTLRAHIDYSYKTAHTIYGILGVKVWLFKGEKIITDKVDN
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PTH_PHOPR
Sequence: MSNNIRLLVGLANPGAEYAKTRHNAGAWVVQELARVHNVSLREESKYFGVTGRITTNGQDLRLLIPTTYMNLSGKSVAALANFFQIKPEEILIAHDELDLPPGVAKFKKGGGHGGHNGLRDTISKMGNNKEFYRLRVGIGHPGDKNKVANFVLGKAPVKEQECIDAAVDEAVRCMDILLKDGLNKAQNRLHSFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC7_CHACT
Sequence: VLVASLVMLEAQSSDTIQVPDWGKRLLMNHDSNRVGIPCGESCVWIPCLTAIAGCSCKNKVCYT
What is the function of this protein?
Probably participates in a plant defense mechanism (Probable).  Active against E. coli ATTC25922 but not against S. aureus ATCC 12600 or S. epidermidis ATCC 14990 (PubMed:22467870).  Has cytotoxic and hemolytic activity (PubMed:22467870).
What are the official names of this protein?
Chassatide C7, Cyclotide chaC7.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: CP52K_CANMA
Sequence: MVFTAFILEYWYFTLLSLAAGHFIGKHVYTNYLMRKHHAEPILDVVDDGAFGFKFGFQALKAKKIGKQIDLLFKKFNEAKHPSIGTFVTRSFGMQFIATKDPENIKAMLATQFNDFTLGQRLSYFAPLLGKGIFTLDGEGWKHSRAMLRPQFSRDQVGHVKMLEPHFQLLKKHIIKNKGSFFDIQELFFRFTVDSATEFLFGESVSSLKDESIGYDQEEIDFAGRKDFAEAFNKSQVYLSTRSLLQLLYWLVNSSDFKRCNKIVHKFSDYYIKKALTATPEELEKHSSYIFLYELAKQTRDPIVLRDQSLNILLAGRDTTAGLLSFAVFELGRNPEVWSKLREEIGDKFGLDPDSRIEDISFELLKLCEYLKAVINETLRLYPSVPRNGRFAAANTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYGKDANEFRPERWFEPEVRKLGWAFLPFNGGPRICLGQQFALTEASYVLVRLIQSFETLELSPDAPYPPAKLTHLTMCLFDGAPVRIE
What is the function of this protein?
Together with an NADPH cytochrome P450 the enzyme system catalyzes the terminal hydroxylation as the first step in the assimilation of alkanes and fatty acids.
What are the official names of this protein?
Cytochrome P450 52A11, Alkane-inducible P450-ALK8, CYPLIIA11.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: DUT_KLEP3
Sequence: MMKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELAPGATTLLPTGLAIHIADPSLAAVILPRSGLGHKHGVVLGNLVGLIDSDYQGQLMVSVWNRGQQSFIIEPGERIAQMVFVPVVQAEFNLVEEFDATDRGEGGFGHSGRK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: ISCS_ACIBC
Sequence: MKRPIYLDYAATTPVDPQVAERMMECLTFDGTFGNAASRSHAYGWQAEEKVEYAREQVANLIKADPREIVWTSGATESDNLALKGVAQFYASKGKHIITSKIEHKAVLDPCRELEEQGFEITYLEPEPQTGLITPEMVKAALRPDTILVSLMMVNNEIGTVTDVAAIGELTRANKTFFHVDAAQAAGKVDIDLSTMKIDLMSFSAHKIYGPKGIGALYVRRSPRVRLKAQIHGGGHERGMRSGTLATHQIVGMGEAFELAGKTMHAEQERIRKLRDKLWNGLQDLEQVFLNGHPTQNVANYLNVSFNFVEGESLMMSLKDAAVSSGSACTSATLEPSYVLRALGLSDELAHSSIRFSFGKYTTEEDIDHVLTITKAAVEKLRELSPLWDMYKEGIDLSTVEWAEH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_RALSO
Sequence: MARIAGVNIPNHKHTVIGLTAIYGIGRSRARKICEATGIPTDKKVKDLTDPDQDALRKEIEKFLVEGDLRRETTMNIKRLMDLGCYRGVRHRKGLPLRGQRTRTNARTRKGPRKAGVALKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: LEPA_AFIC5
Sequence: MTTTPISNVRNFSIVAHIDHGKSTLADRLIQTTGGLQDREMKEQVLDSMDIERERGITIKAQTVRLRYKAKDGKDYILNLMDTPGHVDFAYEVSRCLAACEGALLVVDASQGVEAQTLANVYQAIDNNLEIVPVLNKVDLPAAEPDQVKQQIEDVIGIDASEAIMVSAKTGIGIPDVLEAIVTRLPPPKGDRDATLKALLVDSWYDVYLGVVVLVRVVDGVLKKGDRIRMMGTNAAYDVERVGVFTPKMVNVDELGPGEVGFITAAIKEVADTRVGDTITDDRKPITEMLPGFKPAIPVVFCGLFPVDADDFETLRGAMGKLRLNDASFSFEMETSAALGFGFRCGFLGLLHLEIIQERLSREFNLNLIATAPSVIYKMHLTDGQEIEIHNPIDMPDVVKIAEIEEPWIEATIMTPDDYLGAVLKLCQERRGTQKELTYVGSRAMAKYELPLNEVVFDFYDRLKSVSKGYASFDYHLTDYKAADLVKMQILVNNEPVDALSMLVHRSRAEGRGRAMVEKMKELIPPHMFQIPIQAAIGGKVIARETVRALRKDVTAKCYGGDITRKRKLLEKQKEGKKKMRQFGKVDIPQEAFIAALKVDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IF2_BACC1
Sequence: MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQTEKPSVADEFEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTTFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIYEGQLDTLKRFKDDVKEVAQNYECGITIEKYNDLKEGDIIEAYIMEEVKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_BLOPB
Sequence: MIHGIGIDIVDIRKIKKIITHSGDKLATRILSKSEWKIYKNKKHPVHFLAKRFAAKEAVSKAFGTGINQGVTFNQIEIFNDKLGKPMLHLFSCTALLANKLSLKKMHITLSDTNSYACAFVILER
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_GEOAE
Sequence: MALNLRKNHQILKIINDALIDLPTPSNISTWWNFGSLLGICLITQIVTGLLLAMHYTADTNLAFSSVAHMCRDVQFGWLIRNLHANGASFFFICIYLHIGRGLYYGSYLNKETWNIGVILLLTLMATAFVGYVLPWGQXSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIVGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYTIKDILGFVLMLSLLVSLALFAPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASILVLFLTPLLHTSKLRSMTFRPLSQILFWTLVANVLILTWVGSQPVEHPFIIIGQLASFTYFTIILILFPLAAALENKLLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BCHL_DINSH
Sequence: MSPLDTAPPVLKGEDGEGSVQVHQDDSMKIEGAKVFSVYGKGGIGKSTTSSNLSAAFSKLGKRVLQIGCDPKHDSTFTLTGSLVPTVIDILKEVDFHAEELRPEDFVFEGFNGVKCVEAGGPPAGTGCGGYVVGQTVKLLKQHHLLEDTDVVIFDVLGDVVCGGFAAPLQHADRALIVTANDFDSIYAMNRIIAAVQAKSKNYSVRLAGCVANRSRETDEVDRYCKTVGFNRIAHMPDLDAIRRSRLKKKTLFEMEDAEDVVQVRKEYIRLAETLWNGTEPLAPAPLPDREIFELLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: PPK5_PSEBJ
Sequence: GGGGSGETSGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, FXPRL-amide, PseBi-Capa-PK.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: COX6C_NYCCO
Sequence: MASSALAKPQMRGLLARRLRIHIVGAFVVSLGVAAFYKYAVAEPRKKAYADFYRNYDSVKYFEEMRKAGVFQSVK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6C, Cytochrome c oxidase polypeptide VIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6c family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: MTBA_METBA
Sequence: MAEYTPKERLYRALRKQQVDRMPAVCFTQTATVEQMEACGAYWPEAHSDAEKMATLAEAAHTVVGFEAVRVPFDITAEAEFFGCGIKAGDLKQQPSVIKPSVKNLEDLEKLKNYNLKEGRIAVVLEAVKILSEKYGKELPIIGSMIGPFSLAQHINGDAWFGNLFTGEEVVPALLDFCSDFNVAYAKAMVENGADTIAIIDPTASYELIGGEFYEKYALPYQKKIVDAMKELDVATVLHICGNTTNGLGIMDKTGVNGISVDQKVDIKTATGSVKNAIIVGNLDPVAVLWNGTPEEIAEASKKALDAGVGLLTVGCGTVSMTPTVNLQKMIECAKSHTY
What is the function of this protein?
Methyltransferase involved in methanogenesis from methylamines methanol pathway.  Catalyzes the transfer of the methyl group from the methylated corrinoid protein MtmC (MtmC1 or MtmC2) or MtbC to coenzyme M, forming the substrate for coenzyme-B sulfoethylthiotransferase.
What are the official names of this protein?
Methylcobamide:CoM methyltransferase MtbA, MT2-A, Methylcobamide:CoM methyltransferase II isozyme A, [Methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family. MtbA/MtaA subfamily.
Protein: ISDC_STAAB
Sequence: MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTNDTSIANDYFNKPAKYIKKNGKLYVQITVNHSHWITGMSIEGHKENIISKNTAKDERTSEFEVSKLNGKVDGKIDVYIDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKNSASGSDKGSDGATTGQSESNSSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFVRKKSKGNVE
What is the function of this protein?
Involved in heme (porphyrin) scavenging.  Binds hemoglobin and almost exclusively free-base protoporphyrin IX.  Probably has a role as the central conduit of the isd heme uptake system, i. e.  mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF.  Hemin-free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor.  The reaction is reversible (By similarity).
What are the official names of this protein?
Iron-regulated surface determinant protein C, Staphylococcal iron-regulated protein D.
What is the protein family that this protein belongs to?
Belongs to the IsdC family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan- anchor. Note=Anchored to the cell wall by sortase B (By similarity).
Protein: PTH_DESDA
Sequence: MDYNGVLVGLGNPGARYEGTRHNCGFALIDAFVDFGYRHGTVDEMNGGKFSCQLWRVRLPRLDGCWLAAKPQTFMNLSGQCVQPLLSWHKLKAADLVVAHDELDIPPGELRFKFGGGNAGHNGLKSITELLGTPDFYRLRMGIGRPPHKGDVTNWVLGRPQGEDAENLDHILPLALDVLFAFADKGLDSAVRLAGKTTRPRKPVRQTANAEASNNSPEASATPQNKDNT
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_LEPCP
Sequence: MSRVGKMLVAVPQGVDVSINEDLISVKGSLGTLLRPAHRLVKVQNEAGKLSFTPLDESAEANAMSGTMRALVANMVNGVSKGFQKKLSLVGVGYRAQAQGQKLNLQIGFSHPVVKEMPEGIKVECPTQTEILIKGADRQVVGQLAAEVRAFRPPEPYKGKGIRYSDEKVAIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: LANN_STRMG
Sequence: MSNTQLLEVLGTETFDVQEDLFAFDTTDTTIVASNDDPDTRFKSWSLCTPGCARTGSFNSYCC
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
What are the official names of this protein?
Lantibiotic mutacin-1140, Mutacin III.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.
Protein: PFA3_YARLI
Sequence: MQCRKCCFACEKWCFIGAKAFLPLVVNFLIIWACWVHAWLVCWEPQLFESDTTFWRVYGVAGVAIGIMCNVLYLKVCKVGPGSPTDIDNFSVPLVEYQNACSAEGQHLTPPREMANSVCAKENGGLRFCTKCIGWKPDRSHHCSNYKRCVLKFDHYCPWFATAIGFHNHKYFVLFLWYVTILCFFCLGSTGFVFYNHILEIGAMRGPDGNTDYVGAISVNVMILMVLALVFAIAVGTFATFSLYLVFNNQSTVEFLESTQYRSAVPTAAYRYTFAPTSKTVGNVFDVGWKRNFQLVMGDKWWMWLLPIQPSEAARGNGTQFPLNKQVLQKIREAAAKEVQIRDQNQAYIKQQRQQQQKRTQYDLPQHLQPPPQEHYEYDDEAQDSGDDIPLINMVNKNNTK
What is the function of this protein?
Palmitoyltransferase specific for VAC8.  Palmitoylates VAC8 at one or more of its N-terminal cysteine residues, which is required for its proper membrane localization (By similarity).
What are the official names of this protein?
Palmitoyltransferase PFA3, Protein fatty acyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA3 subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: UIMC1_PIG
Sequence: MPRRKKKGKEASGAQNLEKKDAETASSVSVKKKRRIEDGFIVISDSDGEEPKEENGLQKTKIKQSSRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNSCRPSDASATRSRPLATGPSSESHQEKSTDSGTTEGIWQLVPPSLFKGSHISQGNESEEREEPWDHNENTEEEPVSVSSGSWDQSSQPVFENENVKCFDRCTGHLAEHTQCGKPQNECGRGSAFLKAVQGSGDTSRHCLPTLADAKGLQDTGGTVNYFWGIPFCPDGVDPNQYTKVILCQLEVYQKSLKMAQRQLLNKKGFGEPVLPRPPSLIQNECGQGEQASEKNEGISEDMGDEDKEERQESRASVWRAKTKDFQEGPIKTLKEKLLLEEEPTTSHGQSSQGLFVEETSEEGNSVPASQSIAALTGKRSSVLMPESSAEEITVCPETQLSSPETFDLEKEGFPDSRETLYEVSIMADKEVDNREDAKKEIHTSTFSSSTQVSCPLCDQGFPPTKIERHAMYCNGLMGGDTVLTRRQKEAKNKSDNGIAAQTSLDIDKNEKCYLCKSLVPFREYQCHVESCLQLARVDQGDGPEESGRLCLAVDGKRPQQLKNLKEKDRSEGRLISLLEQSEYKTTDAEIKTKFSETGDFRVPSAGVEEAGCSREMQSSLAHLDLNESPIKSFVSVSEAADCLVDFKKQLTARPGSRTRTKAGRGRRRKS
What is the function of this protein?
Ubiquitin-binding protein.  Specifically recognizes and binds 'Lys-63'-linked ubiquitin.  Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs).  The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.  Also weakly binds monoubiquitin but with much less affinity than 'Lys-63'-linked ubiquitin.  May interact with monoubiquitinated histones H2A and H2B; the relevance of such results is however unclear in vivo.  Does not bind Lys-48'-linked ubiquitin.  May indirectly act as a transcriptional repressor by inhibiting the interaction of NR6A1 with the corepressor NCOR1.
What are the official names of this protein?
BRCA1-A complex subunit RAP80, Receptor-associated protein 80, Ubiquitin interaction motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RAP80 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Protein: NDPA_SALG2
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTTTVVEMVAELHRVYSAKNKAYGLFNEESELAQALRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGIVLFCHYRYLAVEYLLVTVLNNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPQSTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELSGVSEVSFSEFTAEKGYELEESFPADRSTLRQLTKYAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLREQLQRRTSGEK
What are the official names of this protein?
Nucleoid-associated protein YejK.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CA1A_CONCN
Sequence: MGMRMMFTVFLLVVLTTTVVSFPSDSASDGRDDEAKDERSDIYESKRNGRCCHPACGKYYSCGR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (PubMed:10320362, PubMed:28238803).  CnIA and CnIB block muscular nAChR alpha-1/gamma and alpha-1/delta subunits (PubMed:10320362).
What are the official names of this protein?
Alpha-conotoxin CnIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.