PharMolix/UniProtQA huggingface dataset:
Protein: IHFA_AERHH
Sequence: MALTKADIAEHLFTQLGMSKREAKDMVEAFFEEIRQALERGEQVKISGFGNFDLREKNQRPGRNPKTGEDIPISARRVVTFRPGQKLKARVENVEPNE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ARLY_BIFLD
Sequence: MTENNEHLALWGGRFTSGPSPELARLSKSTQFDWRLADDDIAGSRAHARALGRAGLLTADELQRMEDALDTLQRHVDDGSFAPIEDDEDEATALERGLIDIAGDELGGKLRAGRSRNDQIACLIRMWLRRHSRVIAGLLLDLVNALIEQSEKAGRTVMPGRTHMQHAQPVLLAHQLMAHAWPLIRDVQRLIDWDKRINASPYGSGALAGNTLGLDPEAVARELGFSRVTDNSIDGTAARDLVAEFAFVAAMTGVDISRLSEEIIIWNTQEFAFVKLDDGYSTGSSIMPQKKNPDIAELARGKSGRLIGDLTGLLATLKGLPTAYARDLQEDKEAVFDQVDTLEVLLPAFTGMVRTMHFDGDRLEEEAPTGFALATDIAEWLVKNGVPFRHAHELSGACVKLAEGRGQELWDLTDNDFIETFAAFLPADKAPGVREVLSSHGSVDSRNGKGGTAYGRVREQIADAKAEVEELKLFPASTSDGSAYKAPGTF
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRK_SALPB
Sequence: MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIPATAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEVSELKELHDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPDIYHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCDLQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRWFRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAYGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGVWSSLAETGEKLVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMPR_ASCSU
Sequence: MPRIEFEPKLDFKDVLLRPKRSTLRSRAEVDLMREYVFRNSKKTYVGVPVVASNMDTVGTFEMAEVLAKFSLFTTIHKHYQVDEWKAFVQRVDSNPQIMSQIGISSGISTSDFDKLRTVCDMIPELEYICLDVANGYSEVFVDFIRRVREQFPTHTIFAGNVVTGEMVEELILSGADVVKVGIGPGSVCTTRKKAGVGYPQLSAVLECADASHGLNGHVMSDGGCTNPGDVAKAFGGGADFVMIGGLLAGHDQCGGEVVEKDGKKYKLFYGMSSDTAMKKYQGSVAEYRASEGKTIYMPYRGDVSRTIHDLLGGLRSACTYIGATKLKELSKRATFVRVTQQTNDQYSAYEVPRID
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: PIMT_BURTA
Sequence: MSGERAKRFPLALEDLKREPRKPEGRAAERQAAGDAARQRLIAAAAAAPAAASPIAPERLAPRAAGASGSGVPVAKPARAKPPTTPGVAKSAPSSGVKNGDKSATPNVALSGALALTSERVRERMVERLRANGVADPRVLAAMSAVPRHMFVDPGLAAQAYEDAALPIGHQQTISKPSVVARMIELAAAGRTLERVLEIGTGCGYQAAVLSRVARDVYSIERVKPLYERAKLNLRPLRVPNIRLHYGDGRVGLPAAAPFDAIVIAAAGLDVPRALLEQLAIGGRLVAPVGEQAGEQVLTLVERVAPAQWRESRLDRVFFVPLKSGVI
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_BORPA
Sequence: MSKPALRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQKALKGVIMELEDCAFPLLHEVTAHSDPRTAFKDADVALLVGARPRGPGMERKDLLSVNAQIFTAQGRALNDVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRALSQLSAKSGKRVADIEKLIVWGNHSPTMYPDFRFATVGGQGLTQLINDDAWNRDTFIPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGSNGKWVTMGIPSDGSYGIPEGIIYGFPVVTENGEYKMIKDLEIDAFSRERLDFTLKELLEERDGVKDLLK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: YPFN_SALPA
Sequence: MDWLAKYWWILVLVFLVGVLLNVIKDLKRIDHKKFLANKPELPPHRDFNDKWDDEEDWPKKDQPKK
What are the official names of this protein?
UPF0370 protein YpfN.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RR11_ORYSI
Sequence: MTKAIPKIGSRRKVRIGLRRNARFSLRKSARRITKGVIHVQASFNNTIITVTDPQGRVVFWSSAGTCGFKSSRKASPYAGQRTAVDAIRTVGLQRAEVMVKGAGSGRDAALRAIAKSGVRLSCIRDVTPMPHNGCRPPKKRRL
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LGT_AZOBR
Sequence: MLAIAFPGIDPVAFELGPIVIRWYALAYLAGFVLGWRYCLALARSTPGRPSAEDYDDFLTWAVVGVILGGRIGYVLFYNLPFYLQNPLDALMVWHGGMSFHGGLIGVLGAILLFCWKRGLSPLAFGDLIAAAAPIGLFFGRIANFINGELYGRPAPDVSWAVVFPRDPLQVPRHPSQLYESFLEGAVLFVLLAILVRMPAVRGRAGMTAGIFFIGYGLSRIIAEFFREPDAQLGFLYAGATMGQLLSVPMVLFGVWLVAQARRRPAAI
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DER_ACIBS
Sequence: MKPVIALIGRPNVGKSTLFNQITKSRDALVADFAGLTRDRKYGDATYQNKSFIVVDTGGIGESEGGIDNYMAEQSKTAINEADIIIFVVDARAGLLASDEQIARELRTLGKKIYLVANKVDGVHAEAALVEFYKLGLGEPLQVAASHGRGVQQMLEDVLQDIPEDENPEEHDKDTGLRLAIIGRPNVGKSTLVNRLLGEDRVVAFDQPGTTRDSIYIPFEREGRKYTLIDTAGVRRKGKVDEMIEKFSIVKTLQAMKDAHVVVVVVDAREGIVEQDLHLIGYALEAGRAMVIAINKWDNMSEYDRKQCKLDVERRFDFIPWARIHLISALHGTGVGELYPSIHRAYESANLKVSPAKLTQILNDATDQHQPPTVQGRRIKMRYAHMGGQNPPTIVIHGNKVDKTPADYRRYLENVFRKVYKLEGTPVKIEFKTSENPFEGRKSQVDERTAARRRRYIQKFKKAEKKFKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: MURG_LEPIC
Sequence: MKSIVIVAGGTGGHISPGVALAEVLTELKEKIGYENLYLYSLVRNKNNPDLEQAPCPVLWHNLPPLSSNFFLFPIRYTIQIIKTFFIFKKLNIDVVIGMGGYSTVSSILYGIFFRKKIYLCEQNTIPGNVNRLFFRFASKVAFSLPPKNSKIPCDYQVLGNPLRKKTIPKMSLKFFEKYDTKKKKQFNVLVMGGSQGARQINNIVIALMSHEEINKQFRFRVLTGSALYEEVSKKSKKDAELISYSDNMKEHYEWANFVIARSGSGVLSECAAFALPMILIPYPYAKDDHQMANAKYFELNGAAIVVDQKDEDESHLFRVLDQMANDVNLLNDMSISSLECSHVDASKDTAKYFFSLD
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL9_SHESW
Sequence: MNVILLDKIANLGNLGDQVVVKAGYARNYLLPQGKAVVANESNVKVFEARRAELEAKLAAELAAANQRAEKITALEAVVIASKAGDEGKLFGSVGNRDIADAVTAAGVELAKSEVRLPLGALRTTGDFEVEVQLHTEVKAVVKVSIVAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SFNAD_STAA8
Sequence: MNLNLIFKEQTLKFNKEEQETYLFLQQHNSDWANIFKEMILQGRDKVTQRLVTSMHRENLVKARTQSKKILSRDLIMLDISTTHILEIQFPQAKQTLYAPITGEHAFDRIDVEGPFYIKDDITNTITRVHHPNEILECILIEAPDLKNAASDQFQQDLINSATNMTFAISYQALSMQHDSAPLFNIIENSEDSYLRSEQAVIEGHPLHPGAKLRKGLNALQTFLYSSEFNQPIKLKIVLIHSKLSRTMSLSKDYDTTVHQLFPDLIKQLENEFTPKFNFNDYHIMIVHPWQLDDVLHSDYQAEVDKELIIEAKHTLDYYAGLSFRTLVPKYPAMSPHIKLSTNVHITGEIRTLSEQTTHNGPLMTRILNDILEKDVIFKSYASTIIDEVAGIHFYNEQDEADYQTERSEQLGTLFRKNIYQMIPQEVTPLIPSSLVATYPFNNESPIVTLIKRYQSAASLSDFESSAKSWVETYSKALLGLVIPLVTKYGIALEAHLQNAIATFRKDGLLDTMYIRDFEGLRIDKAQLNEMVYSTSHFHEKSRILTDSKTSVFNKAFYSTVQNHLGELILTISKASNDSNLERHMWYIVRDVLDNIFDQLVLSTHKSNQVNENRINEIKDTMFAPFIDYKCVTTMRLEDEAHHYTYIKVNNPLYRENN
What is the function of this protein?
Involved in the biosynthesis of the siderophore staphyloferrin A.  Catalyzes the ATP-dependent condensation of D-ornithine and citrate to form a citryl-D-ornithine intermediate.
What are the official names of this protein?
D-ornithine--citrate ligase.
What is the protein family that this protein belongs to?
Belongs to the IucA/IucC family.
Protein: KBAY_ECO7I
Sequence: MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFDENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANLISA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires KbaZ subunit for full activity and stability.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Ketose 1,6-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily.
Protein: FA53C_PONAB
Sequence: MITLITEQLQKQTLDELKCTRFSISLPLPDHADISNCGNPFQLVSEGASWRGLPHCSCAEFQDSLNFSYHPSGLSLHLRPPSRGSSPKEQPLSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRPCATSPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSLDFDKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSASCSPTGGSSQVLSESEEEEEGAVRWGRQALSKRTLCQQDFGDLDLNLIEEN
What are the official names of this protein?
Protein FAM53C.
What is the protein family that this protein belongs to?
Belongs to the FAM53 family.
Protein: BECN1_PIG
Sequence: MEGSKTSSSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLATAQVKPGETQEEEANPGEEPFIETRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMHEDDSEQLRMELRELALEEERLIQELEEVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQMQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
What is the function of this protein?
Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors.
What are the official names of this protein?
Beclin-1.
What is the protein family that this protein belongs to?
Belongs to the beclin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells. SUBCELLULAR LOCATION: [Beclin-1-C 35 kDa]: Mitochondrion. Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Beclin-1-C 37 kDa]: Mitochondrion.
Protein: DNLI4_COCIM
Sequence: MDRLNNVGGETERELDEKYPNRPRNKHSTLPFHDLFLTLFNPLNGNKKRPTGPAAARKKLGPHGGQQTLSPQELRRDIIQRFISRWRKEVGNDIYPAFRLIIPEKDRDRAMYGLKEKTIGKLLVKIMKIDKNSEDGFNLLNWKLPGQSMASRMAGDFAGRCYEVISKRPIRTDVGNMTIQEVNDKLDVLAATSKEDEQIPVLEEFYRNMNPEELMWLIRIILRQMKVGATERTFFEIWHPDAESLFSISSSLRRVCWELYDPNVRLEADEARVTLMQCFQPQLAQFQMHSFPKMIERMRLSPDDPTFWIEEKLDGERIQLHMMSDDSIPGGKRFGFWSRKAKDYTYLYGNGFYDENGALTRHLKDAFADGVDNIILDGEMITWDPEQDAPLPFGTLKTAALSEQRNPFSATGQRPLFRIFDILYLNDKALTRYTLRDRRRALEASIKPVHRRLEVHTYEIGNSAADIEPQLRKVVAEASEGLVLKNPNSPYRLNDRHDDWMKVKPEYMTEFGESLDCVVIGGYYGSGKRGGGLASFLCGLRVDEAQVRQGASPMKCYSFLKVGGGFTAPDYANIRHHTDGKWKDWNPKKPPTEFIELAGGDAQYERPDVWIRPDESVVLCVKAASVTPSDQFRLGLTVRFPRFKRLRMDKDWKSALSIQEFMDLKANAEREQKEKEFKIDNSRRKRAKRAVKKPLTIAGYDESKRAGFTGPSGHVFEGMNFFVITDSVEPEKKSKLELEQLIKANGGKIYQTHTAAPNTLCIAERRTVKVASVQKVAKESIIRPSWLFDCIKQNEVDKGLPDLLIPFEPRHMYFTVKSQEEEIARHVDEYSDSYARDITPNELSKLLVSMPLIPNLPPPHISKTETQIQERESTFQELRGWLFKNQVLHFVKRRSDSMLSLPLRLASNLARFAGASVANELEDKSITHVVIDTDSQPADVSALRSAISKRVAAGRRIPHLVTIAWIQDSWKAESLLDEERFAPTA
What is the function of this protein?
Involved in ds DNA break repair.  Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining.
What are the official names of this protein?
DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZIP6_ARATH
Sequence: MASCVTGTEAAIRAAACRDGEEASHLKIVAVFAIFLTSVFGVWGPVLLAKYFHGKPLYDKAILVIKCFAAGVILSTSLVHVLPEAFESLADCQVSSRHPWKDFPFAGLVTMIGAITALLVDLTASEHMGHGGGGGGDGGMEYMPVGKAVGGLEMKEGKCGADLEIQENSEEEIVKMKQRLVSQVLEIGIIFHSVIIGVTMGMSQNKCTIRPLIAALSFHQIFEGLGLGGCIAQAGFKAGTVVYMCLMFAVTTPLGIVLGMVIFAATGYDDQNPNALIMEGLLGSFSSGILIYMALVDLIALDFFHNKMLTTCGESGSRLKKLCFVALVLGSASMSLLALWA
What is the function of this protein?
May play a role in the transport of zinc in the plastids.
What are the official names of this protein?
Zinc transporter 6, chloroplastic, ZRT/IRT-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HYPA_CALS4
Sequence: MHELSVTQGLVDMLVEEAEKRKVKKVTKVTVVIGELTGIESESVKFYFDILTENTVAEGAELVFKIVRAQFKCTQCGNVFERSNFTFKCPVCGGQGVLIDKRGKEFYIESIEVE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: FOSB1_BACAA
Sequence: MLKGINHLCFSVSNLEDSITFYEKVLEGELLVRGRKLAYFNICGVWIALNEEIHIPRKEIHQSYTHIAFSVEQKDFERLLQRLEENDVHILQGRERDVRDCESIYFVDPDGHKFEFHSGTLQERLNYYREDKPHMTFY
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB 1, Fosfomycin resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTC38_XENLA
Sequence: MAPLSLRDCKAWQDAGLTLSTTSNEVCKLFDATLIQYATWKNDSTLGGIEGCLSRINNTDPNFVMGHVAANGLELIGTGRSPLVDKELDDALKTMSDLSKSQALTEREKLHVAAVETFADGNLPKAADLWERILQSHPTDLLALKFAHDCYFYLGEQRQMRDSVARVLPYWKPETPLSSYVKGMYSFGLLETNFYDQALKVAKEALAVERTDSWSVHTIAHVHEMKADLDSGLSFMQETENNWKGSDMLACHVYWHWALYLIEKGDYEAALTLYDNHIAPQCFASGSMLDVVDNSSMLYRLQMEGVNVGDRWKNLVQITKKHTKDHMLIFNDLHFLMSSLGSKDEDTTRQLVESMQELSKSPGEKQQHSLIKHLGAPLCQALIEYNGGNYDKAVDLIYPIRYQILKIGGSDAQRDLFNQVLIQAAINSDSTHHQNLARVLLMERDIGRPNSPLTQRLIKKWEALHGLLG
What are the official names of this protein?
Tetratricopeptide repeat protein 38, TPR repeat protein 38.
What is the protein family that this protein belongs to?
Belongs to the TTC38 family.
Protein: ACTE_STRPU
Sequence: MCDDDVAALVVDNGSGMVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVFDSGDGVSHTVPIYEGYALPHAIIRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAASSSSLEKSYELPDGQVITIGNERFRASETLFQPSFIGMESAGIHETCYNRIMKCDVDIRKDLYVNTVLSGGSTMFPGIADRMQKEISALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, cytoskeletal 3A, Actin, cytoskeletal IIIA.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: GATE_PYRAB
Sequence: MMVMTDKFNYEELGLKVGLEIHRQLDTKKLFSPVPSELSDKVEFTFQRRLRPTMSELGEIDPAALEEFKKGRVYVYEGNYELTDLVYMDEEPPRGPDREALEVALQIAYLLNAKPVDEVYYMRKIVIDGSNVSGFQRTAIIATDGKVETPWGAVGIPTICLEEDAARIIERKDKEVIYRLDRLGIPLIEISTTPDIHHPEQAKVVAKFIGDALRATKKVKRGLGTIRQDLNVSIKGGARIEIKGVQELDMIPIIIEREVERQLNLLKIRDELRKRGVKPKDIKEEFYDVTDIFENTKSKIIARVIKKGGKVLAIKLPKFRGLIGREIQPGRRLGTEFADRAKKYVPGIFHIDELPNYGISQEEVNKVIERLNLSEEDAFVLVAAEEEKAKNALREVIKRAREAIEGVPEETRRALPDGNTEYMRPLPGKARMYPETDIPPLRIPDDLKKKIKENLPELPQAKVERYVKEYKLDRSLAQTLVDDERDELFEELVSMGVKPSLAASILVVVLKGLRKEVPIENVTDEHIREAFQLYLEGKIAKEAFEEIFKELARNPSKSAREVAEEKGLTLLSEEEVTRIIEEVIQQNIEVVKAKGMGAMGLIMGRVMAKVRGKADGKLVSQIVRRKLQEISGG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: INKA1_HUMAN
Sequence: MDMHSARLDSFLSQLRWELLCGRDTGSPSMPGPLQPTSQTGPDVQPSHQLRASGALEEDSVCCVEEEEEEEEEAVVTEDRDAALGGPREHALDWDSGFSEVSGSTWREEELPVSQRPAPSAQPLRRQCLSVSGLPMPSRAPVASVPPVHHPRPKSTPDACLEHWQGLEAEDWTAALLNRGRSRQPLVLGDNCFADLVHNWMELPETGSEGGDGGGHRARARPPQFLLGLSEQLRRRLARARRTAMAGKRLSCPPRPEPELPADVSRFAALMSCRSRQPIICNDVSYL
What is the function of this protein?
Inhibitor of the serine/threonine-protein kinase PAK4 (PubMed:26607847).  Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity (PubMed:26607847).
What are the official names of this protein?
PAK4-inhibitor INKA1, Induced in neural crest by AP2-alpha protein homolog, HInca, Inka box actin regulator 1.
What is the protein family that this protein belongs to?
Belongs to the INKA family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear (PubMed:26607847). Relocalizes to the cytoplasm following interaction with PAK4 (PubMed:26607847).
Protein: RS19_ECOHS
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ATPA_FRAP2
Sequence: MQLSPSEISGLIKKRIEKFDNSVELKSEGSIVSVADGIVTIYGLDDVTAGEMIKLPGDVYGLALNLNTDSVGAVVLGDYEHIKEGDKAYCTGRILEVPVGEALLGRVVDALGNPIDGRGEIETAHSSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIGRGQRELIIGDRQIGKTAIAIDAIINQKGTGVKCIYVAIGQKASSIANIVRQLEEHGAMEHTIIVAATASDSAALQYIAPYAGCSMGEYFRDRGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVERFTNGEVKGKTGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLFNSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQFRELEAFSQFASDLDEATRSQLNRGQRVTELLKQKQFSTLSIALMALSLYAADNGYLDSLEVSEVIPFESALHALAENKYAEVVAEINETGKYDAEIAEKLKTIVEDCKANQAW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARL1_CAEEL
Sequence: MGGVMSYFRGLFGAREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVEQVEYKNLKFQVWDLGGQTSIRPYWRCYYANTDAIIYVVDSADRDRVGISRQELATMLQEDELQGAVLAVLANKQDIAGCLTETEVYKALGLDALRNRTIQIFKTSASKGEGLDPAMDWLANQLQQKK
What is the function of this protein?
GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.  Plays a role in male tail tip morphogenesis (PubMed:21408209).
What are the official names of this protein?
ADP-ribosylation factor-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasm. Cytoplasmic granule. Note=Localizes to cytoplasmic granules (puncta) during the later stage of male tail tip retraction.
Protein: VF170_IIV3
Sequence: MIASFDIGIKNFAFAVKRDGEFVLVENVNLLGDFVTKNDLNKTPKSALVEMMDRLNLDSKGQIKKTMVESILTAQKKSSPKQRAIDLGVKLFETMDRYRSFWTECDTFLVERQMVSNMQALKLSHYLEAYLKIHYPDKSVVNYSASNKTRKLGAPPLPTKPDRKRWTVEYAASILTGRHLDKFQSCPKKDDLADVVCMIEAYQKM
What are the official names of this protein?
Uncharacterized protein 97L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 170L family.
Protein: RAS_SCHPO
Sequence: MRSTYLREYKLVVVGDGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKKCEIDGEGALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYNITSRSSFDEISTFYQQILRVKDKDTFPVVLVANKCDLEAERVVSRAEGEQLAKSMHCLYVETSAKLRLNVEEAFYSLVRTIRRYNKSEEKGFQNKQAVQTAQVPASTAKRASAVNNSKTEDEVSTKCCVIC
What is the function of this protein?
Participates in the process of sexual differentiation and the determination of cell shape.  Essential for mating and for recognition of the mating pheromone, but not for vegetative growth.  Does not regulate the intracellular cAMP level.  Regulates two downstream pathways, namely the byr2/byr1/spk1 mitogen-activated protein kinase cascade and the cdc42 small G protein pathway.  The former is relevant to mating and sporulation, whereas the latter is relevant to mating, cell growth and cell morphology.
What are the official names of this protein?
Ras-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.