PharMolix/UniProtQA huggingface dataset:
Protein: Y1622_MYCPA
Sequence: MTTPQFGSQRSDDDNWDIVSSVGYTALLVAGWRALHAVSPRPLVRDDYAKTFIAASGDPYLTGVLANPGTSEDELAFPRLYGAQTRFFDDFFDAAGAAGIRQAVIIAAGLDSRAYRLEWPPATTVFEVDLAKVLEFKARVLGEQGAVPKARRVEVAADLRADWSRPLEAAGFDVESPSAWSVEGLLPYLTDEAQHALFTRISGLSAPGSRIAIGALGSRLDHDQLHALEESHPGVDVSGNVDFSALTYEPQSDPAEWLAAHGWVVDPVRNTLDLQAGYGMTPPEVDVKIDGFMRSQYITAAR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_1622c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: AMPX_VIBPR
Sequence: MKYTKTLLAMVLSATFCQAYAEDKVWISIGADANQTVMKSGAESILPNSVASSGQVWVGQVDVAQLAELSHNMHEEHNRCGGYMVHPSAQSAMAASAMPTTLASFVMPPITQQATVTAWLPQVDASQITGTISSLESFTNRFYTTTSGAQASDWIASEWQALSASLPNASVKQVSHSGYNQKSVVMTITGSEAPDEWIVIGGHLDSTIGSHTNEQSVAPGADDDASGIAAVTEVIRVLSENNFQPKRSIAFMAYAAEEVGLRGSQDLANQYKSEGKNVVSALQLDMTNYKGSAQDVVFITDYTDSNFTQYLTQLMDEYLPSLTYGFDTCGYACSDHASWHNAGYPAAMPFESKFNDYNPRIHTTQDTLANSDPTGSHAKKFTQLGLAYAIEMGSATGDTPTPGNQLEDGVPVTDLSGSRGSNVWYTFELETQKNLQITTSGGYGDLDLYVKFGSKASKQNWDCRPYLSGNNEVCTFNNASPGTYSVMLTGYSNYSGASLKASTF
What are the official names of this protein?
Bacterial leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RAC2_DROME
Sequence: MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKRHKCALL
What is the function of this protein?
Involved in integrin alpha-PS3/beta-nu-mediated phagocytosis of Gram-positive S. aureus by hemocytes.
What are the official names of this protein?
Ras-related protein Rac2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ZN704_MOUSE
Sequence: MQARRLAKRPSLGSRRGGAAPAPAPEAAALGLPPPGPSPAAAPGSWRPPLPPPRGTGPSRAAAASSPVLLLLGEEDEDEEGAGRRRRTRGRVTEKPRGVAEEEDDDEEEDEEVVVEVVDGDEDDEDAEERFVPLGPGRALPKGPARGAVKVGSFKREMTFTFQSEDFRRDSSKKPSHHLFPLAMEEDVRTADTKKTSRVLDQEKETRSVCLLEQKRKVVSSNIDVPPARKSSEELDMDKVTAAMVLTSLSTSPLVRSPPVRPNEGLSGSWKEGAPSSSSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRSPAPPDDGIDEADASNLLFDEPIPRKRKNSMKVMFKCLWKSCGKVLNTAAGIQKHIRAVHLGRVGESDCSDGEEDFYYTEIKLNTDATAEGLNTVAPVSPSQSLASAPAFPIPDSSRTETPCAKTDTKLVTPLSRSAPTTLYLVHTDHAYQATPPVTIPGSAKFTPNGSSFSISWQSPPVTFTGVPVSPPHHPTAGSGEQRQHAHTALSSPPRGTVTLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID
What is the function of this protein?
Transcription factor which binds to RE2 sequence elements in the MYOD1 enhancer.
What are the official names of this protein?
Zinc finger protein 704, Glucocorticoid-induced gene 1 protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNZ2_RAT
Sequence: MWALRSLLRPLGLRTMSQGSARRPRPPKDPLRHLRTREKRGPGWGPGGPNTVYLQVVAAGGRDAAAALYVFSEYNRYLFNCGEGVQRLMQEHKLKVARLDNIFLTRMHWSNVGGLCGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIDLAVRPHSAPEYKDETMTVYQVPIHSERRCGEQEPSRSPKRSPNRLSPKQSSSDPGSAENGQCLPEGSSAGVNGKAWGRDPSLVVAFVCKLHLRKGNFLVLKAKELGLPVGTAAIAPIIAAVKDGKSITYEGREIAAEELCTPPDPGLVFIVVECPDEGFIQPICENDTFQRYQGEADAPVAVVVHIAPESVLIDSRYQQWMERFGPDTQHLILNENCPSVHNLRSHKIQTQLSLIHPDIFPQLTSFHSKEEGSTFSLPTVRGECLLKYHVRPKREWQRDTTLDCNTDEFIAEALELPNFQESVEEYRKNMQASPAPAEKRSQYPEIVFLGTGSAIPMKIRNVSSTLVNLSPDKSVLLDCGEGTFGQLCRHYGQQIDRVLCNLTAVFVSHLHADHHTGLLNILLQREHALASLGKPFQPLLVVAPTQLRAWLQQYHNQCQEILHHISMIPAKCLQKGAEVPSPPVERLISLLLETCDLQEFQTCLVRHCKHAFGCALVHSSGWKVVYSGDTMPCEALVQMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAIGVGMRMNAEFIMLNHFSQRYAKIPLFSPDFNEKVGIAFDHMKVCFGDFPTVPKLIPPLKALFADDIEEMVERREKRELRLVRAALLTQQADSSEDREPHQKRAHSEEPHSPQSKKVRAQ
What is the function of this protein?
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity.  Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.  Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
What are the official names of this protein?
Zinc phosphodiesterase ELAC protein 2, ElaC homolog protein 2, Ribonuclease Z 2, RNase Z 2, tRNA 3 endonuclease 2, tRNase Z 2.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Nucleus. Note=Mainly mitochondrial.
Protein: DER_PSELT
Sequence: MATVVIAGRANVGKSTLFNRLIGRRKAITEKIEGVTRDIIKGLVVYNETSFLLYDTCGVFESTRDPVLLAMRDKAFEAFRKADLILFVVDGRSGITSEDEYVAQQLRKIAKKVLMVINKSENMSVVEKNLPDIMKLGFAEYIPVSAQHGNNIDELLDKITNLLRESGEKSMLFKESSPKIAIVGKPNVGKSSLFNALLNMDRATVTPVPGTTRDPVDEMIEINGKKYILVDTAGMRRKSRIERKTIEQFSISRTIDTIQSADVVLLVIDATEGVTRQDKRIADLILSSGRAMVCVINKFDLVNVRKKDYEAALFTEMPFINFCRIVFTSAVKKSGLEKLFNAIDEAYESYCRKVPQQLLSKLASQLPLLSPALSRKNLRIYSIKQIKIKPPKFVIMVNKKELTDYQTEKTLQRFIRERVDQFTGTPLVIEFKSRR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SYH_BUCBP
Sequence: MKEIIRSIKGMHDYIPDDVITWQYIEYIVKRILKNYCYNEIRFPLIEKTSLFAHSIGNITDIIEKEMYSFKDKKNKKITLRPEGTIGCMRACINKGLLRTSKQKLWYLGPMFRYERPQHGRYRQFHQFGIEVLGMSGPDIDLEIILLVERILRTLNISNYVQLELNSIGSYESRLHYKKILFSYFKQYEACLDEDCKRRLYVNPLRILDSKDKNIKAIINNAPILMDFIDDNSLIHFENLCKLMKNIGISYVVNYKLVRGLDYYNKTVFEWKTNLLGAKDAICAGGRYDNLSKSLGVTFIPAIGCAIGMERLVLLIKSLKLKPKTNNAIDVFIIFLKDNIQIEAIKLSELVRTQFPKKKIMLSILSSNLRKQFSTANKIKARIVLLLGPNEVKNNLILLKDLTSGYQKSFLKNKIIEELELAFKN
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_STRZP
Sequence: MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRDFVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHFMPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDAPIYYYGFEAEGNDFVASDLIRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIGLLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKYPSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLANKINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIGB_YERPB
Sequence: MNILNLKIIMFLLISNIIVVGGAWATSTCPDWPATRIAVEINALEQQLNKWSAAYHQQGHSPVTDDIYDQLQDKLRVWQSCRGLPDKTESQPIPGKGQFLHPVAHTGLKKLKDETALTRWMAGRKNLWVQPKVDGVAVTLVYHGGKLVQLLSRGNGVKGQNWTEKAPFISAIPQYIANAPALLTLQGELFLLMDGHQQAKSGGVNARSTVAGALMRKSPSPLLAQVGVFIWAWPDGPTTMKEKVALLQVMGFPFTAKYSEPVMSHLDVVQWRQFWFQAPLPFVTDGVVVRQEEEPAGRYWQATPGQWSMAWKYPPLQHIAEVKDIHFTLGRTGKGTVVLEVLPIKIDDKWIRRVNIGSVTRWKQWDIAPGDHITLALAGHGIPRLDNVVWRVHQRNTITAPNWDKFHQLSCFQRLPHGCEPQFLSRLIWLSGPGGLDIGGIGGGFWQKLIHHELINDLVGWLLLTPEQIASIPGIGNARAEKIYQQFQRAKQQPFSRWLLALGFPQVVSVDAQWQVVLRRSLSEWATMAGIGQMRAKQIKHFLDHPDVQALADFLSTQKVVGFELTE
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: LEU1_STUS1
Sequence: MTMLKNPSNKYRAFPAIDIPDRTWPSKAITQAPIWLSSDLRDGNQSLIEPMDAAKKMRFFKTLVQVGLKEIEVGFPSASQTDFDFVRELIEGGHIPDDVTIQVLTQAREDLITRTFESLKGAKQAIVHYYNATAPSFRRIVFNQDKAGVIQIAVNAGRIIKRLAEQNPETNWRFEYSPEIFSSTEPEFAVEVCNAVIEVFQPTPEQKLILNLPATVEAATPNVYADQIEWFCRHIDRRDSVLVSLHTHNDRGTGVAATELGLMAGADRVEGCLFGNGERTGNVDLVTVALNMYTQGVDPQLDFSDIDAVRKVVEECNQLPVHPRHPYVGDLVHTAFSGSHQDAIRKGFSQQDPNGLWEVPYLPIDPADIGRSYEAVIRVNSQSGKGGITFLLEQEYGISLPRRMQIEFSQVVQKETDRLGLEMSAKQIYALLEAEYLQATAPYTLKGHRLQEENGTSAVDVEVAADGEVIHWRGIGKGPLEALVAALPVKLEIMDYHEHAIGAGSNAKAAAYIEVRLDGERPLHGIGIDENITTASIRALFSAMNRALHQAQEAAA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: RPOY_STAAN
Sequence: MAVFKVFYQHNRDEVIVRENTQSLYVEAQTEEQVRRYLKDRNFNIEFITKLEGAHLDYEKENSEHFNVEIAK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: RECX_LACPL
Sequence: MTKKVTKIVAQKRAGRYNIYLDEQYAFPISESVMIKFRVFKGMEVDEQLQAAMIAADDVSKAYTRALDYLSHQLRTEKEVHDKLRDEEIDESVIDATMQQLRDMRLLNDQQYADAFVRTAKRTSDKGPRVIRQNLRQKGVGEQLIDDALAGQFSAEEQIDNASELARKLAKRYHRQAFKTMQQKVRQGMMTKGFDNDTITAAIASLALEPDEDEQWEALVAQGTKLWQRNRKYAFRERMMRTKRSLFQKGFMMDDINRFIDEQVADE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP28_GIBZE
Sequence: MPLDIEELLRKKKAADTAAAKPRFIPKAERERLAAEKAKKEEDDKKRKASEEEQKRKEEEQKWRSNGSSRPNESNGSGRVPTGPRSMNDGRDDRERDRDRDQGRGRVRGKDRKGDKQGVGADKQSAEDIEATLLRSRYLGPQVNQQSNFSAKKKRMRTTEKKFNFEWDADEDTSRDNDPLYDRQTAVSHNGSFAGIGGEFDDGAEERARKRAKMIAQRDPENGKERAEGIMEDFFRARDKARQRADRRGLGKHWSEKSLDDMRERDWRIFKEDFGIATKGGMIPNPMRSWQESNLPQRLLNIVDDVGYKDPSPIQRAAIPIALQARDLIGVAVTGSGKTAAFLLPLLVYISDLPPLDEINKHDGPYALIMAPTRELVQQIETEARKFAGPLGFRVVSIVGGHQIEEQAYNLRDGAEIVVATPGRLLDCIERRLLVLSQCCYVIMDEADRMIDLGFEESVNKILDALPVTNEKPDTDEAENAQIMQRYLGGRDRYRQTMMYTATMPPLVERIAKKYLRRPAIVTIGNAGEAVDTVEQRVEFVSGEDRRKKRLQEILSSGNFGPPIIVFVNIKRNCDAVARDIKQMGWSAVTLHGSKTQEQREAALGSVRAGHTQVLVATDLAGRGIDVPDVSLVVNFNMATNIESYTHRIGRTGRAGKSGVAITFLGPEDHETMYDLKQILSKSSISKVPEELRRHEAAQSKPVRGAKKDKDEGSGKGNWQH
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA splicing.  May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site.  May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NDK_HERA2
Sequence: MEKSLIILKPDAVQRGLIGPILTRLEARGLKFIGIKLSQVSSELAHKHYGVHEGKPFFAGLVSYITSGPVLVVAVEGKDVIEIVRSTVGATNPVKAAPGTIRGDFGVNIGRNLIHASDSPENGDHEVALFFSSEELIRSERSVDQWITE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V16K_TRVTC
Sequence: MTCVLKGCVNEVTVLGHETCSIGHANKLRKQVADMVGVTRRCAENNCGWFVCVIINDFTFDVYNCCGRSHLEKCRKRFEARNREIWKQVERIRGEKASATVKKSHKSKPSKKKFKERKDFGTPKRFLRDDVPLGIDQLFVF
What are the official names of this protein?
16 kDa protein.
Protein: CDC7_HUMAN
Sequence: MEASLGIQMDEPMAFSPQRDRFQAEGSLKKNEQNFKLAGVKKDIEKLYEAVPQLSNVFKIEDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTHDTKIELLKFVQSEAQQERCSQNKSHIITGNKIPLSGPVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGERNFNIHSSISHESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVCSICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKTFGKSILCSKEVPAQDLRKLCERLRGMDSSTPKLTSDIQGHASHQPAISEKTDHKASCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPDEAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL
What is the function of this protein?
Kinase involved in initiation of DNA replication.  Phosphorylates critical substrates that regulate the G1/S phase transition and initiation of DNA replication, such as MCM proteins and CLASPIN.
What are the official names of this protein?
Cell division cycle 7-related protein kinase, CDC7-related kinase, HsCdc7, huCdc7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HXB6_MOUSE
Sequence: MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFAASSYYPPAGGGYGRAAPCDYGPAPAFYREKDAACALSGADEPPPFHPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKPAE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B6, Homeobox protein Hox-2.2, Homeobox protein MH-22A.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_CLOP1
Sequence: MANIKSAKKRIKVTEKKTLRNKMIKSALKTAIKKFEVAVEANNKAEAATLYVEAARALDMSASKGVVHKNMAARKKSRLAAKLNAMA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RSMG_SALTY
Sequence: MLNKLSRLLADAGISLTDHQKTLLVAYVDMLHKWNKAYNLTSVRDPNEMLVRHILDSIVVAPYLQGQRFIDVGTGPGLPGIPLAIVLPDAHFTLLDSLGKRVRFLRQVQHELKLENITPVQSRVEAYPSEPPFDGVISRAFASLNDMVSWCHHLPGEKGRFYALKGQLPGDEIASLPDNFSVESVEKLRVPQLEGERHLVIIKSNKV
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_MOOTA
Sequence: MKAKEIRDLTTEELRQKVNELKQELFNLRFQLATNQMDNPMRLKEVRRSIARAKTILRERELKQQRA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RS18_PORGI
Sequence: MAANNQGEIRYLTPLSVDTKKKKYCRFKKSGIRYIDYKDPEFLKKFLNEQGKILPRRITGTSLKFQRRVAQAVKRARHLALLPYVTDMMK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MET_MUNMU
Sequence: MKSPAVLAPGILVFLFTFVQKSDGECKEALVKSRMNVNMQYQLPNFTAETSIQNVVLHKHHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGVWKDNINMALLVDTYYDDQLISCGSVHRGTCQRHVLPPNNTADIESEVHCMYSPQADEETSQCPDCVVSALGTKVLLSEKERFINFFVGNTINSSYLPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLPELQDSYPIKYVHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSTDSGLHSYMEMPLECILTEKRRKRSTKQEVFNILQAAYVSKPGAQLARQIGANLNDDILYGVFAQSKPDSSEPMNRSAVCAFPVKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTEFTTALPRVDLFTGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSLTPHVNFRLDSHPVSPEVIVEHPPNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPSFVQCGWCRDKCVRLEECPSGTWTQETCLPAIYKVFPTSAPLEGGTTLTVCGWDFGFKRNNKFDLKKTRVLIGNESCTLTLSESTTNMLKCTVGPAMNEHFNMSIVISNSRGSVQYSTFSYVDPIITSISPNYGPKTGGTLLTLTGKHLNSGNSRHISIGGKTCTLKSVSHSILECYTPAQSTPSEFSIKLKIDLANREVNSFIYREDPIVYEIHPTKSFVSGGSTITGVGKNLNSVSILRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNPVFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIVGVVSISIILLLLLGLFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNASQNGSCRQVQYPLTDLSPILTSGDSDVSSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDALYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNVNGEGDT
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RSMH_BURM7
Sequence: MGNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGDAGRLIAFDKDPRAIETAESIEDARFEIVHDSFAAMKGALDARGVGRVSGVLLDLGVSSPQVDDPARGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLVVISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPRPPLKLLGRMFPNDAEVAANPRARSAVMRIAERVAP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPIB5_HUMAN
Sequence: MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKVINTLADHHHRGTDFGGSPWLHVIIAFPTSYKVVITLWIVYLWVSLLKTIFWSRNGHDGSTDVQQRAWRSNRRRQEGLRSICMHTKKRVSSFRGNKIGLKDVITLRRHVETKVRAKIRKRKVTTKINHHDKINGKRKTARKQKMFQRAQELRRRAEDYHKCKIPPSARKALCNWVRMAAAEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSITDNSLSLKTPPECLLTPLPPSADDNLKTPPECVLTPLPPSADDNLKTPPECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTPLPPSALPSAPPSADDNLKTRAECLLHPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTALPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAFHPQRMISRHLPSVSSLPFHPQLHPQQMIISRYLLSVCGFRFHHQPMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGGRFHPERMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGGRFHPQQMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGGRFHPQRMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGGRFHPQQMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGGRFHPQRMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPPLATQEAEAEKPRKPKRQRAAEMEPPPEPKRRRVGDVEPSRKPKRRRAADVEPSSPEPKRRRVGDVEPSRKPKRRRAADVEPSSPEPKRRRVGDVEPSRKPKRRRAADVEPSLPEPKRRRLS
What are the official names of this protein?
Nuclear pore complex-interacting protein family member B5.
What is the protein family that this protein belongs to?
Belongs to the NPIP family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HEMH_RHOBA
Sequence: MSELPPYDSFLLVSFGGPEGQDDVMPFLENVLRGKNVPRERMLEVAEHYKHFGGVSPINEQNRQLIAALQKRFDANGIDLPIYWGNRNWDPYFADTLRQMKADGKKRSLAFFTSMFSCYSGCRQYRENIIQAREEVGEGAPLVEKVRMGFNHPGFIAAMADNVSKAAQTIGASPARTKVLFTAHSIPMGMADNCDYEKQLRESCRLVADACGAVDWDLVYQSRSGPPSQPWLEPDVLDAIAEMDDAKKLESLVILPIGFVSDHMEVLFDLDEEAAQLCRERGIKMARASAAGTHPDFVEMICGLVQERLGKLNEKPALGELGPWHDVCPQDCCLYTPRRPPVAGGRPVQAN
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_ACET2
Sequence: MPKVDVYDINGKVVGEINLRDDIFGIEVNKHAIHQVIVNQLANRRQGTQSTKTKSEVRGGGRKPWRQKGTGRARHGSIRSAQWVKGGIALGPKPRSYKYAVPKKLRRLALKSALSSKVNENELLVLDSLNFDEIKTKQMANVLKNLKVNDTTAVLVLADKNRNVELSARNIPGLKTLFVNTMNVYDIIRHDKFIITKDAVAKVEEVYA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PGSC2_DROME
Sequence: MANKALILLAVLFCAQAVLGVTIISKSEWGGRSATSKTSLANYLSYAVIHHTAGNYCSTKAACITQLQNIQAYHMDSLGWADIGYNFLIGGDGNVYEGRGWNVMGAHATNWNSKSIGISFLGNYNTNTLTSAQITAAKGLLSDAVSRGQIVSGYILYGHRQVGSTECPGTNIWNEIRTWSNWKA
What is the function of this protein?
N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN).  Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments.  Has no direct bacteriolytic activity (By similarity).
What are the official names of this protein?
Peptidoglycan-recognition protein SC2.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.