PharMolix/UniProtQA huggingface dataset:
Protein: NUOD_AZOC5
Sequence: MAHTLDSQQPAVPVRNFQINFGPQHPAAHGVLRMVLELNGEVVERVDPHIGLLHRGTEKLIEAKTYLQAVPYFDRLDYCAPMNQEHAFCLAVERLAGIEVPKRGQLIRVLYSEIGRLLSHLLNVTTFAMDVGALTPPLWGFEAREKLMMFYERASGSRMHAAYFRPGGVHQDLPQKLVEDIGEFCRTFPSLLDDLDALVTGNRIFKQRTVDIGVVTLEDALAWGFSGVMVRGSGAPWDLRRAQPYECYSELDFDIPIGKHGDCYDRYVVRMEEMRQSNKIMLQCVDRLLKEAGPVASTDRKVSPPKRGEMKRSMEALIHHFKLYTEGFHVPEGEVYAAVEAPKGEFGVYLVGDGTNKPYRCKIRAPGFAHLQSMDFLCRGHMLADVSAVLGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HEM3_STAA9
Sequence: MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLFVKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEIIKRLNEQH
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: NSP5_ROTH7
Sequence: MSLSIDVTSLPSISSSIYKNESSSTTSTLSGKSIGRSEQYISPDAEAFNKYMLSKSPEDIGPSDSASNDPLTSFSIRSNAVKTNADAGVSMDSSTQSRPSSNVGCDQVDFSFNKGIKMNANLDSSISISTNSKKEKSKNEHKSRKHYPKIEAESDSDDYVLDDSDSDDGKCKNCKYKRKYFALRMRMKQVAMQLIEDL
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RL20_SHEHH
Sequence: MPRVKRGVTARARHKKVLKLAKGYYGARSRTYRVAVQAVTKAGQYAYRDRRQKKRQFRQLWIARINAASRQNGLSYSRFINGLKKASIEIDRKILADIAVFDKVVFATLVEKAKDALAK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TGT_CAMLR
Sequence: MEFKVEYKSANARACRIKTTHSEILTPAFMPVGTLAAIKSLDAIDMSEILDAKIILANTYHLYLRPSSKVIKQMGGLHGFSKFDRSFLTDSGGFQAFSLNKISKPDEEGIKFKSHIDGSLHYFTPKSVLDAQYDFNSDIMMILDDLVALPASKERIELSLKRTIKWAKEAIDYHKLKQNQGVGMGQNIFGIIQGGTDFEARRICSQALCEMDFDGLAIGGLSVGEENEVMYDTVEAMMPYVDNNRPRYLMGVGTPEDLVENVARGVDMFDCVMPTRNARNGTLFTSFGKFNIKKAEFITDHSPIDSKCSCYTCKNFSRAYLNHLFKAKELTFFRLASLHNLHYYLNLAKQMREAIIKNEFENFKKEFYRQRTC
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TRPA_STRGC
Sequence: MTKTLTQHLETIKREGKGIFLPYIMAGDHEKGLAGLAETIAFLENLGVSAIEIGLPFSDPVADGPVIEEAGLRSLGHHTSAKSLVASLQKLDTQLPLIIMTYFNPIFQYGLKDFVKDLATTPVKGLIIPDLPYEHRNFILPLLEDSDLALIPLVSLTTGLERQQELIKEAEGFIYAVAINGVTGKSGSYRNDLDQHLSKLHDIAEIPVLTGFGVSTLEDVDRFNQVSDGVIVGSKIVKALHEKDDSIAAFIQEAAAYKK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: HIS6_CORA7
Sequence: MALAVRVIPCLDVDNGRVVKGVNFENLRDAGDPVELAARYGQVGADELTFLDVSASKDGRGTMLDVVRRTADQVFIPLTVGGGVRSVDDVRELLRAGADKVSVNSSAIARPELLRELADVFGSQCIVLSVDARRAADFPSGFEVTTHGGTRSAGLDAVEWAKRGEELGVGEILLNSMDGDGTKAGFDIELIEAVRAAVSVPIIASGGAGKAEHFPPAVDAGADAVLAASIFHFGEVEISEVKEALAAAGKEVRQ
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_STRA3
Sequence: MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSLKGYYKGRKIAKANEAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SF3B3_DANRE
Sequence: MFLYNITLQRATGISHAIHGNFSGTKQQEIVVSRGKILELLRPDANTGKVHTLLTMEVFGVVRSLMAFRLTGGTKDYVVVGSDSGRIVILEYHPSKNMFEKIHQETFGKSGCRRIVPGQFLAVDPKGRAVMIGATEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENPMFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEALEEHGNFLITVPGGSDGPSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFFFLAQTEQGDIFKVTLETDEEMVTEIRMKYFDTIPVATAMCVLKTGFLFVSSEFGNHYLYQIAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDEQESLSPIMSCQIADLANEDTPQLYVACGRGPRSTLRVLRHGLEVSEMAVSELPGNPNAVWTVRRHVEDEFDAYIIVSFVNATLVLSIGETVEEVTDSGFLGTTPTLSCSLLGEDALVQVYPDGIRHIRADKRVNEWKTPGKKTIIRCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQRSRFLAVGLVDNTVRIISLDPSDCLQPLSMQALPAQPESLCIVEMGGVEKQDELGEKGTIGFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSWLSYSYQSRFHLTPLSYETLEYASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFPLQYTPRKFVIHPETNNLILIETDHNAYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAAAFLNENLPEAIFGAPKAGSGQWASLVRLINPIQGNTLDLVQLEQNEAAFSVAICRFLNGGDDWYVLVGVARDMILNPRSVGGGYIYTYRIVGGGDKLEFLHKTPVEDVPLAIAPFQGRVLVGVGKLLRIYDLGKKKLLRKCENKHVPNLVTGIHTIGQRVIVSDVQESLFWVRYRRNENQLIIFADDTYPRWITTACLLDYDTMASADKFGNICVVRLPPNTSDDVDEDPTGNKALWDRGLLNGASQKAEIIINYHIGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDFFQHLEMHMRSEFPPLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMDPHKQKSVSEELDRTPPEVSKKLEDIRTRYAF
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome.  SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA.  Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.  May also be involved in the assembly of the 'E' complex.  Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
What are the official names of this protein?
Splicing factor 3B subunit 3.
What is the protein family that this protein belongs to?
Belongs to the RSE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATP8_CANPA
Sequence: MPQLVPFYFMNLLTGGILAISLLLYFVATYLLPNILRLLIARNIIIKL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: CHEB_YERPS
Sequence: MSKVRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAYSELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLIAIGASTGGTEAIRAVLQPLPPTSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARSGANYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGAYTLAQNEASCVVFGMPREAIAMGGVNDVVELNQISQRMLAQISSGQALRI
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDA1_YEAST
Sequence: MAPIFRNYRFAIGAFAVIMLILLIKTSSIGPPSIARTVTPNASIPKTPEDISILPVNDEPGYLQDSKTEQNYPELADAVKSQTSQTCSEEHKYVIMIDAGSTGSRVHIYKFDVCTSPPTLLDEKFDMLEPGLSSFDTDSVGAANSLDPLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDGVSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVFEPTFPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNTKTHQLSSPCLPPKVNATNEKVTLESKETYTIDFIGPDEPSGAQCRFLTDEILNKDAQCQSPPCSFNGVHQPSLVRTFKESNDIYIFSYFYDRTRPLGMPLSFTLNELNDLARIVCKGEETWNSVFSGIAGSLDELESDSHFCLDLSFQVSLLHTGYDIPLQRELRTGKKIANKEIGWCLGASLPLLKADNWKCKIQSA
What is the function of this protein?
After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol.
What are the official names of this protein?
Guanosine-diphosphatase, GDPase.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
Protein: TAL1_SHISS
Sequence: MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGYETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARITESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase 1.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_MARMS
Sequence: MGSLTKADLAENLVDSIGLSKKDAKDLVEGFFDVVRSSLIERQQVKLSGFGNFEVREKSQRPGRNPKTGEEIPITARTVVTFRPGQKLKSKVEDYMQE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: CF418_DANRE
Sequence: MADDLDDLLDEVESKFCCNTSESKQTSRVMKHTDQKCDNLEERKLPRKQGRKRVENEIDIDAMLHEILDDDVDTPTSTHEPSPAKASSSAQTISKKCCPVFLGGSSVAHGIGTSVSERACNRLRCTYCDFSVITFDDHEWDSSCDYLFFRNNMPDYHKLKVHLRRRAGVRAYACQCSWISILTLSHLREQPQLKWVCGKHRA
What is the function of this protein?
May be involved in photoreceptor outer segment disk morphogenesis (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 418.
What are the subcellular locations of this protein?
Cytoplasm. Photoreceptor inner segment.
Protein: TPC2L_XENTR
Sequence: MAVCVAVIAKENYPLYIRSTPTENQLKFHYTVHTSLDVVDEKISAMGKAVMDQRELYLGLLYPTEDYKVYGYVTNSKVKFVMVVDSSNTSLRDNEIRSMFRKLHNSYTDVMCNPFYNPGDPIQSRAFDNTVTSMMVPAC
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 2-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. Sedlin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Endoplasmic reticulum. Golgi apparatus.
Protein: ASNA_ACTP2
Sequence: MKKTFILQQQEISFVKNTFTQYLIDKLGIIEVQGPILSQVGNGMQDNLSGIEKAVQVNVKCIPGATFEVVHSLAKWKRHTLARFGFKEGEGLFVHMKALRPDEDSLDPTHSVYVDQWDWEKVIPEGRRNFDFLKETVNEIYKAIRLTELAVEARFDIPSILPKQITFVHSEELVQRYPNMTGKERENAICKEHGAVFLIGIGGKLSDGKPHDGRAPDYDDWTTESENGYKGLNGDILVWNEQLGTAFELSSMGIRVDEKALRLQVELTGDQDRLEMDWHKDLLAGRLPLSIGGGIGQSRLVMFLLRKAHIGEVQSSVWPKAMLEKYKNIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXP21_ORYSJ
Sequence: MAPPSLPILLVLLSLSSSLSSSSAAAAGRWTDAHATFYGGADASGTMGGACGYGNTYGQGYGTDTAALSAVMFGDGLSCGACFELRCGGGGGGDRRGCLPPAAGKSIVVTATDLCPANHALPGDRGGWCNPPLHHFDLSQPAFLRIARFQSGIVPVSYRRVACRRKGGMRFTINGHSYFNLVLVSNVGGAGDVHAVAVKAGGGRKARWQAMARNWGQNWQSGALLDGQALSFTVTTGDRRSVVSYNVAPAGWAFGQTFTGRQFT
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
What are the official names of this protein?
Expansin-A21, Alpha-expansin-21, OsEXP21, OsEXPA21, OsaEXPa1.21.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: RNPH_HALHL
Sequence: MRPSGRRADELRPISIQRQFTKHAEGSVLIGFGDTRVLCTASVEARVPPWLRGQGRGWVTAEYGMLPRSTHTRSDREAARGKQQGRTVEIQRLIGRSLRAAVDLQALGERSVVVDCDVLQADGGTRTAAITGAFVALTDALEGLVRQRALPASPLHGQVASVSVGVYRGEPVLDLDYAEDGEAETDMNVVMNDAGAFIELQGTAEGHAFRRDELDRMLALAEKGVGELLQHQQEALAT
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: MEIS3_XENTR
Sequence: MAQRYDEMVHYPGLDGMPLAGFGDAHTGRALQHHSLSQSAPYGSTGAAHRVPMPPGMGSNDGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDNSGSFPGGDVCSSDSFNEDIAVFAKQVRTEKPLFSSNPELDSLMIQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIDDRDGSSKSDLEDFTGSCTSLSDQNNSWIRDHDETGSTHSGTPGPSSGGLASQSGDNSSEQGDCMDNSVASPSTGDDDDLDRDKKRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTGQGGAPYSPDGQNMGGYVMDGQQHMGIRPPGFQGIPGDYTAAPSTMPMGFPPAGYTPAIPPHSAGLRHGPSLHSYLPGHPHHASMILPAGASPHHLVSAQSPADALLNGQNIDIHAH
What is the function of this protein?
A caudalizing protein which is required to pattern the anterior/posterior (A/P) axis during central nervous system (CNS) formation.  Inhibits anterior neural expression and acts as a transcriptional activator to induce posterior neural gene expression.  Maintains a proper A/P balance required for hindbrain formation by activating the FGF/MAPK pathway, which modulates the planar cell polarity (PCP) pathway.  Interacts with retinoid signaling during hindbrain patterning (By similarity).
What are the official names of this protein?
Homeobox protein meis3.
What is the protein family that this protein belongs to?
Belongs to the TALE/MEIS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECR_BORPA
Sequence: MDPQLPEPEPLIALIEALRRLPGVGVRSARRMAYHLLQHDLQGADMLGRALSGAVQHLRHCARCNSFTEDEVCATCANPKRDPGLLCIVETPADQNMIESSHGYRGLYYVLMGRIAPLEGVGPRELDFQRVIERACDGVVQEVILATNFTAEGETTAHFLGDALSERGLKVTRLARGVPAGSELEYVDAGTIAWALMERRST
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: Y6891_RHOJR
Sequence: MSGHSKWATTKHKKAVIDAKRGKAFAKLIKNIEVAARTGGGDPAGNPTLYDAIQKAKKTSVPNDNIERARKRGAGEEAGGADWQTIMYEGYGPNGVAVLIECLTDNRNRAAGEVRTAMTRNGGNMADPGSVSYLFTRKGVVTLEKGDQSEDDVLMAVLDAGAEEVTDLGDTFEIVSEPTDLVAVRSALQEAGIDYDSAEADFRASVEVPVDADGARKVFKLVDALEESDDVQNVYTNVDLSDEVLAELDD
What are the official names of this protein?
Probable transcriptional regulatory protein RHA1_ro06891.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_CYAP4
Sequence: MSSTYKATGINLKAMPLGESDRLLTILTREYGLIRVVAPGARKPRSSLGGRSGLFVVNELLIAPGRSLHKLSQAETLTSYARLSKHLSTLTASQYLAELVIYQALSEQPQVELFDLLCYYLSWLEQSPEQEVLAVLSRAVFHLLEWAGIAPQVQQCCLTRRPITPDYTDPDWRIGFSCRAGGTVTSLAEALSLPASELQSTPAVPSRSAPALEHPHVYLTAIELEVLQHLSTSLPSSPTVSWSDLPPPSHYPTWVWLAIERTLRQYIQSYLDRPIRSAVLMDACFSPLSPAFS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: ROC11_DICDI
Sequence: METSQIRNGFNKVEVDVVGPLKDLLVRVMKNINTPFKILNETFKINYCDQQETKTKSSFYIQTLDANDKSSLELTKSAIKNIQMQQQQQQQQQQQQQQQQHHDIFQFTQPSSSHNHSNHHHHHHQQQLQQQQQQQLQQQMKTPKLLFFIVMSVGVGKSYIKNIKEEAGTIPILEWFTNYIRSWEEVFKLTSNQVTSHIKRQLLTKACTTGNINLLDEILLSGISKEQIKETQTIGHGIILKSLIVNNLDSIVVSGSMSLLGAVIDNDNDKKGSSLILSKLNLNLFPKSIITACFNLAELDLSYNNIKEIPKEICQLKHLKILNMNNNQLDDLPLELANLTNLKYLAVQDNPLNKFPHHIIEQGTKRTLVFLKNIIEGKKSETWNKVKLMFVGQEGVGKSSLCKALMGSRRRSSSSFAAELQKSGDTISTEGVKIQSIKGKKIDFYAWDFGGQQVFYPTHQFFLTNQALYLLVFKLTDPNFAERVNYWTLQIKANSGLSVPMIFLVGTHCDACTPEQLSSAEQILKENFVKYSRIRQNAISFVSCTNGTGIKELKKILTNEAEKSNLIKSNIPGSYLILEQRLTDRGANSSRILINQNNINQNNNNNNNNNNHNNCNNNENCTTTAATAGTTTMTSTTTTTTNYSNENILNTSSNSLIALFTRSNSNSNLSNNYQKPLVNQKYIDYNDFERECKLSHLAQEEIQGATEFLHNMGIILHYDTPILRSLVVLDPQWLADVMSSLITFSHNWIKNGILNHSELVSIWSGKYDQSIWPSLLKLLEKFEVSYELPNEFPSRSLIPSLLPEEPIDRIQEIKEKLWIPLPEAIESKRVQIFGCQYNFDFMPLGFFPRLLLRILLIKGIDIKTYWANGILLDILTTEDIKIQKLNHKKHSILPNNSSSTSSSTSSSTSSSTSSSSSSSTSSSSTSTTTTTVQIQSSPFGNSTTIVNKLTNIDNNNNNNNNNNNNNNNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKNIINNFENQNNLNNIITNNFGGKFEIIKKNDFESPLSSKKPKHQVLVTFKNQKSFESKDKDTYKLNVEIRSFNVSNNNDKDFLASLFFQQLLSTIDTLLSGSYGGLKVTRLIPCIHCIEKDPHSEPHLFDINSCISQLLLGKSQLVCGKDSTTPVRIDYIAPDLSIKKIPILLEDQVVCEEQIGVGGFGLVHKGKLILQDKSLVVAIKSYIVGNSSASDIIRKFQEFHHEMYIMSSLNHLNIVKLFGSMQNPPRMVMEFAPHGDLYHFLEKKKNIKWSFKVRLMLDIAKGIEYLQNQNPPIVHRDLRSPNIFLFSLDENAPVCAKVADFGLSQQSLYSVSGLLGNFQWMAPETIGAEESYTEKIDTYSFSMILFTILTGECPFDEFTSFGKMEFIRKIREEDLRPTIPSDCPPTISNLIELCWSGDPKKRPHFSYIVKELTNFYYNLNLSPIPEQKSINDKSPHPDLISNGVPKLQIAK
What are the official names of this protein?
Probable serine/threonine-protein kinase roco11, Ras of complex proteins and C-terminal of roc 11.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.
Protein: PZRN4_HUMAN
Sequence: MGFALERFAEAVDPALECKLCGQVLEEPLCTPCGHVFCASCLLPWAVRRRRCPLQCQPLAPGELYRVLPLRSLIQKLRVQCDYRARGCGHSVRLHELEAHVEHCDFGPARRLRSRGGCASGLGGGEVPARGGCGPTPRAGRGGGARGGPPGGRWGRGRGPGPRVLAWRRREKALLAQLWALQGEVQLTARRYQEKFTQYMAHVRNFVGDLGGGHRRDGEHKPFTIVLERENDTLGFNIIGGRPNQNNQEGTSTEGIYVSKILENGPADRADGLEIHDKIMEVNGKDLSKATHEEAVEAFRNAKEPIVVQVLRRTPLSRPAYGMASEVQLMNASTQTDITFEHIMALAKLRPPTPPVPDICPFLLSDSCHSLHPMEHEFYEDNEYISSLPADADRTEDFEYEEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGEDVQNREEAVALLSNDECKRIVLLVARPEIQLDEGWLEDERNEFLEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTATSSSNNHEKDSGVGRTDESLRNDESSEQENAAEDPNSTSLKSKRDLGQSQDTLGSVELQYNESLVSGEYIDSDCIGNPDEDCERFRQLLELKCKIRNHGEYDLYYSSSTIECNQGEQEGVEHELQLLNEELRNIELECQNIMQAHRLQKVTDQYGDIWTLHDGGFRNYNTSIDMQRGKLDDIMEHPEKSDKDSSSAYNTAESCRSTPLTVDRSPDSSLPRVINLTNKKNLRSTMAATQSSSGQSSKESTSTKAKTTEQGCSAESKEKVLEGSKLPDQEKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSAVEYAQSQLSLVSMCKESQKCSEPKMEWKVKIRSDGTRYITKRPVRDRILKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVRAKEQRRRREFMMRSRLECLKESPQSGSEGKKEINIIELSHKKMMKKRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV
What are the official names of this protein?
PDZ domain-containing RING finger protein 4, Ligand of Numb protein X 4, SEMACAP3-like protein.
Protein: RSBW_LISMF
Sequence: MATMHDKITLQLPAKPEYVSLGRLSLSGIASRAGFSYEAIEDLKIAVSEAITNSVKHAFKGEDDGEITVEYLIYEDKLEVRVSDNGTSFDLETRKQEIGPYEVGEDAEMMRIGGLGLFLIETLMDDVKLYYDEGVSVVMTKYINEKQVEENAKSIST
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.