PharMolix/UniProtQA huggingface dataset:
Protein: DPOL_BPB03
Sequence: MPRKMFSCDFETTTKLDDCRVWAYGYMEIGNLDNYKIGNSLDEFMQWVMEIQADLYFHNLKFDGAFIVNWLEHHGFKWSNEGLPNTYNTIISKMGQWYMIDICFGYKGKRKLHTVIYDSLKKLPFPVKKIAKDFQLPLLKGDIDYHAERPVGHEITPEEYEYIKNDIEIIARALDIQFKQGLDRMTAGSDSLKGFKDILSTKKFNKVFPKLSLPMDKEIRRAYRGGFTWLNDKYKEKEIGEGMVFDVNSLYPSQMYSRPLPYGAPIVFQGKYEKDEQYPLYIQRIRFEFELKEGYIPTIQIKKNPFFKGNEYLKNSGAEPVELYLTNVDLELIQEHYEMYNVEYIDGFKFREKTGLFKEFIDKWTYVKTHEKGAKKQLAKLMFDSLYGKFASNPDVTGKVPYLKEDGSLGFRVGDEEYKDPVYTPMGVFITAWARFTTITAAQACYDRIIYCDTDSIHLTGTEVPEIIKDIVDPKKLGYWAHESTFKRAKYLRQKTYIQDIYAKEVDGKLIECSPDEATTTKFSVKCAGMTDTIKKKVTFDNFRVGFSSTGKPKPVQVNGGVVLVDSVFTIK
What is the function of this protein?
Polymerase responsible for protein-primed viral DNA replication by strand displacement with high processivity and fidelity.  To start replication, the DNA polymerase forms a heterodimer with a free primer terminal protein (TP), recognizes the replication origins at both 5' ends of the linear chromosome, and initiates replication using as primer the OH-group of Ser-232 of the TP.  This polymerase possesses three enzymatic activities: DNA synthesis (polymerase), primer terminal protein (TP) deoxynucleotidylation, which is the formation of a covalent linkage (phosphoester) between the hydroxyl group of a specific serine residue in TP and 5'-dAMP, a reaction directed by the second T at the 3' end, and 3' to 5' exonuclease activity.  Exonuclease activity has a proofreading purpose.
What are the official names of this protein?
DNA polymerase, Gene product 2, gp2, Protein p2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: HYPF1_CUPNH
Sequence: MRAQTLPAGSDHAPVLACGAWLKNAACLLRGAEVLWSPIHGDLGDPANCDALDQSVEQLLDSAHGQVQAVAHDLHPDFYSTQLAQRLAARLCVPAVAVQHHHAHIAALMAEYDLREPVIGLALDGVGLGTDGTAWGGELLWVSPSEWCRLGHLQSLPLPGGDVAAREPWRMAAAALHVLDRTGEIGRRYGAVVGEQAARTVAAMLERQLNCPRSSSAGRWFDAAAGALGVSVRQQAEAQAAIALEALAADYLSALSPPECVGTYVVDQDGVLDLRGLLEQLFALADEGQAGQAARGAALFHVALAEALVGWAADAAQGHGLKTVALGGGCFMNGILSASVQAGLAARGLQALLPRAVSCGDAGLALGQAWVAARQPTAALAPQTHLQEEGAPCA
What are the official names of this protein?
Carbamoyltransferase HypF homolog.
What is the protein family that this protein belongs to?
Belongs to the carbamoyltransferase HypF family.
Protein: V216_FOWPN
Sequence: MSITSIINNLIDIITLYIRIFYVIYYIAIKSKNQICIANILYTSIKFYYTDIIDAVLKRGIDPNIPFPLSENSYVNPLIYAIECDNHDAILSLIRYGADVNTYSNYLVITPLYISVLHGCPKCVEILLYYGANINIVTYKMVTPIELASRICYNNLAFMVCDRTITNIPKKITYNFEIMKILVSHFILQASNDRLNNRHNKYFSEGYNKNKMLVSTSIILTYFKKQCIEDIDIMKNIKLGDDSFLDILVERNTMKLSTYISNQDILDIPKTVKVYNTRINMLLDEAIIYNNINIIL
What are the official names of this protein?
Putative ankyrin repeat protein FPV216.
Protein: IF1_CHLTR
Sequence: MAKKEDTIVLEGRVEELLPGMHFRVMLENGVPITAHLCGKMRMSNIRLLVGDRVTVEMSTYDLTKARVVYRHR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAPA_ECOLI
Sequence: MRQVLSSLLVIAGLVSGQAIAAPESPPHADIRDSGFVYCVSGQVNTFNPSKASSGLIVDTLAAQFYDRLLDVDPYTYRLMPELAESWEVLDNGATYRFHLRRDVPFQKTDWFTPTRKMNADDVVFTFQRIFDRNNPWHNVNGSNFPYFDSLQFADNVKSVRKLDNHTVEFRLAQPDASFLWHLATHYASVMSAEYARKLEKEDRQEQLDRQPVGTGPYQLSEYRAGQFIRLQRHDDFWRGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAASQLSILRDDPRLRLTLRPGMNVAYLAFNTAKPPLNNPAVRHALALAINNQRLMQSIYYGTAETAASILPRASWAYDNEAKITEYNPAKSREQLKSLGLENLTLKLWVPTRSQAWNPSPLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMSHDLTLSGWATDSNDPDSFFRPLLSCAAIHSQTNLAHWCDPKFDSVLRKALSSQQLAARIEAYDEAQSILAQELPILPLASSLRLQAYRYDIKGLVLSPFGNASFAGVYREKQDEVKKP
What is the function of this protein?
Not part of a putrescine export system (PubMed:27803167).  Very similar to a S. typhimurium protein implicated in antimicrobial peptide resistance, but the SapBCDF operon in E. coli is implicated in putrescine export (PubMed:27803167).
What are the official names of this protein?
Probable ABC transporter periplasmic-binding protein SapA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: QUEC_PSYIN
Sequence: MSKKVVVIYSGGMDSFTVLHKAMQQGLTPYALTFDYGQRHIKEIEVAREVCEELGVHHKVIDISAINQLIGGSSLTDSSIDVAQGHYQQESMKSTVVPNRNMILLSLAIGYAVSLGAEQVYYGAHSGDHEIYPDCRPIFVEKMNDVAAVANYEKVEIFSPYLNNNKSGILKDGLAMGLDYSKTWTCYNGREKACGKCGSCVERLEAFAANGLKDPIAYEDT
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: IF4A2_NICPL
Sequence: MAGSAPEGSQFDARQFDAKMTELLGTEQEEFFTSYDEVYDSFDAMGLQENLLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQLDYSLVECQALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRVFDMLRRQSLRPDHIKMFVLDEADEMLSRGFKDQIYDIFQLLPPKIQVGVFSATMPPEALEITRKFMNKPVRILVKRDELTLEGIKQFYVNVDKEEWKLETLCDLYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRSGRFGRKGVAINSVTKDDERMLFDIQKFYNVVIEELPANVADLL
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-2, eIF-4A-2, ATP-dependent RNA helicase eIF4A-2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: GLMU_SYNWW
Sequence: MKLSAVILAAGKGLRMRSDLPKVAHRVAGKPIILHVIQAVKEAGIEDIVVVVGHGREVVQEICSGEKIRFVLQEQQLGTGHALMQAEAVVAPEDTILVLAGDIPLIQATSLQQLMESHRQKQATATVLSVNMQNPSGYGRILRDQQGAFLRIIEEKDANDEEKKIKEINSGIYCFCARKVFSALHSTSTRNAQGEYYLTEALELLKNQQESIGIFLSDGEEDIYGINDRVQLAQAENILRQRKNRELMLSGVSLMDPASTFIDSDVLIGHDTIILPFTIIEGNSRLGERCEIGPGTRISDSIIGSEVKIESSRLIQASVADRCNIGPFAYLRPETTLLEGVKVGDFVEIKKSTIGTGSKIPHLSYVGDATIGQGVNVGAGTITCNYDGKNKYQTVLEDRVFIGSNTNLVAPVRIGENSITGAGSTISRDVPPHTLAVERAGQKHLPRKG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_ANAPZ
Sequence: MNRSSIRNFAIIAHIDHGKSTLADRLIESCDALAERDMKEQVLDSMDIERERGITIKAQTVRLKYTSKAGEVYYLNLVDTPGHVDFSYEVSRSLAACEGSLLVIDSSQGVEAQTLANVYKAIENNHEIITVLNKVDLVSADPEKVKSQVETIIGLDASDALLVSAKTGIGINDVLEAIIERLPAPEGDEEAPLKAVLVDSWYDPYLGIVILVRIKDGVLKKGMKICMMSTGAVYTVDNVGVFTPHKKMVDALSVGEIGFITAGIKELLACKVGDTVTEDARRCAEALPGFRATCPVVFCSLFPVDAGSFEHLREALGKLQLNDASFTFDIESSTALGYGFRCGFLGMLHLEVVQERLEREFDLDLTATAPSVVYKVTDKRNVTRDIHNPNDLPEAHEILKVEEPWIMATIMVPDQYLGSMLALCNGKRGERVDLSYTGNMALLQYRLPLAEIVFDFYDRLKSISKGYASFDWQMDGYMPAEVSKLTFLINSELVDALACIIHKSKIESRGREICERLKDLIPRQQYKIAIQAAVGSKIVARETISPYRKDVTAKVYGRDVTRKMKLLEKQKKGKKRLRSIGNITVPQSAFIQALQVKD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YIDC_RICAE
Sequence: MNNNIINLIAAIILSLSIIFGWQYFVVKPEQKKQQQQIAVQKAENLKKQQLKAVVEPATGIVVQEESQVQRIKIESESLTGSISLKGLRFDDLILKKYKQDLSKNSPEVRLFSPANTENAYFAEVGLVSNLSSVKLPNNDTIWNSDSEILSPEKPVHLFWVNEDGVKFLVTITVDENYLFTIEQTIVNNSDKELPVQSYGLINRKYIAVEKAVNILHQGPIGCIDENLKEYSYDDIKDKKSEKFVASKVDWIGITDKYWLSSLIPDKSSNYSSNFNYALKQGTERYQVDFISPVQIIKPGEDFSIKSRIFAGAKKVDLLDKYEKQYDIKLFDRAIDFGWFYIITKPVFYAMNFFYGYVGNFGVSILIVTVIIKLLMFTLANKSYRSMKKMKNLQPEIDRIKNLYSDDKARLNQEIMALYKKEKVNPVAGCLPILVQIPVFFSIYKVLYVTIEMRQAPFYGWIKDLSASDPTTIFNLFGLLPFSPPLFLMIGAWPILMAITMFLQQKMSPEPADPMQAQVMKFMPLIFLFMFSSFPVGLLIYWSWNNILSIIQQYYINKFN
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COBQ_SINMW
Sequence: MTRKIMLQGTGSDVGKSVLVAGLCRLASNRGLSVKPFKPQNMSNNAAVSDDGGEIGRAQWLQALAARVPSSVHMNPVLLKPQSDVGSQVVVQGRVAGQARGKEYQALKPGLLGSVMESFELVSAGADLVIVEGAGSPAEINLRAGDIANMGFATRAGVPVVLVGDIDRGGVIASLVGTHAILSDEDRRMVTGYLINKFRGDVTLFDDGIASIRTFTGWPCFGVVPWLKSAGRLPAEDSVVLERLARGGGKALKVAVPVLSRIANFDDLDPLAAEPDVEIVFVRPGTPLPDDAALVVIPGSKSTIADLEDFRRQGWDRDLDRHIRRGGRVIGICGGYQMLGTRVIDPLGIEGGKREIEGLGLLSVETEMAPEKTVRNSRAWSREYGVLLEGYEIHLGRTAGIDCGRAPVEIDGRRDGAMSADGRVMGTYLHGLFGSDPYRAELLRSFGIEGGGGNYRQSVDAALDEIAAELDAVLDRVWLETLLG
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: LUXB_KRYAS
Sequence: MKFGLFFQNFLSENQSSE
What is the function of this protein?
Light-emitting reaction in luminous bacteria.  The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity.
What are the official names of this protein?
Alkanal monooxygenase beta chain, Bacterial luciferase beta chain.
What is the protein family that this protein belongs to?
Belongs to the bacterial luciferase oxidoreductase family.
Protein: MDTB_SHIFL
Sequence: MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLNVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGHAVQAIMDTEKTLNLPVDITTQFGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFARHEEEA
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLB_CELJU
Sequence: MYRLLCLLALLTAAGLMGCASQRGLTPPPDLQAHQQQLQAVASWQIDGKLGIRSPQESGSATLKWQQQPDNYQIYLSGPLGQKRLQIIGAPAAVTLLQSGQPPMHAQSAESLIKKAAGWTLPVSQLSYWVRGLPAPKTPITGLQLSPQGLISELQQANWTIHYSNYRDYYHGETRLALPGKIQAEYRDLRLTLVIRDWQLGIH
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ATPA_SALG2
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPVDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHAPLMQEINQSGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RIHC_KLEP3
Sequence: MRLPIILDTDPGIDDAAAIAAALFAPELELQLMTTVAGNVSVEKTTRNALQLLHFWNADVPLAQGASMPLVRPLRDAASVHGESGMEGYDFVEHQRQPLAKPAFQAIRDALMHAAEPITLVAIGPLTNIALLLTQYPECVFNIRRLVIMGGSAGRGNFTPNAEFNIAIDPEAAAKVFHSGLEIVMCGLDVTNRALLAADYLATLPTLNQTGKMLHALFSHYRSGSMSSGLRMHDLCAIAWLACPELFTLQPCFVAVETQGTWTAGTTVVDIEGRLGQPANALVALDIDVEGFQRWAAEVIALAP
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: H2A4_PSAMI
Sequence: MSGRGKGAKSKSKAKSRSSRAGLQFPVGRVHRFLRKGNYANRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKSRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Late histone H2A.2.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FABH_NEIMF
Sequence: MQYAKISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRHIAAENEKTSDLAAEAARRALDAAGLDSGEIDLIIVATATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANAYIKSGMAKNALVIGAETFSRIVDWNDRTTCVLFGDGAGAVVLSAADKPGIIHSKLKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKFAVKMLSKIADDVIEEAGYTAAQIDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHGNTSAASIPLALDTGIRSGQIKRGQNLLLEGIGGGFAWGAVLLQY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_CLONN
Sequence: MIQELFRKDIKDFRPYDAKGEKYKIKLDANESFIGLSKEIKNKIIRSLIELEFNNYPDPDATKLKKAYGDYIGIDEKNIMVGNGSDELIQILTNAFLDKNEKIVTLNPDFSMYEVYTKVRGGKVSVFDLDEDFKLNVNKIIEYINEEKPKMFIFSNPNNPTGGVIPKYDIIKIIENVNCIVVVDEAYMEFYGDSILDYIKKYDNLIVLRTASKAIGSAALRLGFLITNDTLLREIKKVKPPFNVNSVSQVIGEIILKDKDFIRESIDKVLYERNYLLKELKKIDGLKVYETKSNFVLIYNENANEINESLIKIGIKVRSFTDENLKNFIRITVGSREQNIEVINCIKGDNYDYKEM
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: METAS_METED
Sequence: MLDHGTPIQPVSLPAAELDLGAVGGIAWPEPVQRRLRVGLLNNMPDSALVQTERQFRRLIGPGVELRLFSLDTVPRGPLARAHLDRFYETQGALAGAGLDALVVTGAEPKAERLADEPFFPALAAVVDWADASGVPTLFSCLAAHAAVLHLDGIERRPLPTKHSGIYACTAVAHHPLLAGMPASVPVPHSRWNDLPEQALTARGYRVLRRSEQVGVDLFVRERGASMVFLQGHPEYDGDTLAREYRRDIGRFLDGERDTPPALPENYYVDEAVLRLDAFAAVARAYRSPALHADFPTMAETLPRPAAWQEAAAGLFRNWLALVSDRVALAA
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_CLOD6
Sequence: MKIVFMGTPDIAVPCLQKIIDENYEILGVVTQPDKPKGRGKKLGMSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLGCINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENITAGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAREIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDNVLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: Y1098_METVS
Sequence: MESFLTEIQIRVLNLRKKGHTQEEIAHVMGTSRANISMVEKRARENIEKAKNTLNIYNDIIAPSKIKVEKGTDVFNIPNVIFSKSDEEEIHVNYSSLQIMEFINQNAKRYIKNRMVVEPFIITILQNGEIYVHDFEEEKAKN
What is the function of this protein?
Putative transcriptional regulator.
What are the official names of this protein?
Putative transcriptional regulatory protein Mevan_1098.
What is the protein family that this protein belongs to?
Belongs to the Tfx family.
Protein: RL22_ESCF3
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: OTU1_BOVIN
Sequence: MFGPAKGGHFGVHPAAGCPGGVSQPAAGTKAGPAGVCPVGGRTNAMWRLRCKAKEGTHVLQGLSSRTRVRELQGQIAAITGISPGCQRILVGYPPECLDLSNGDTILEDLPIQSGDMLIVEEDQNRPKTSPAFTKYGAPSYVRETLPVLARMAVPADNSCLFTSVYYVVEGGVLNPACAPEMRRFIAQIVASDPDFYSEAILGKTNEEYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLHLVFPDPDTPPLTIFSSYDDIVLVQALELADEARKKRQFTDVNRFTLRCMVCQKGLTGQAEARDHAKETGHTNFGEV
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins.  May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore.  Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel.  Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains.  Also able to hydrolyze 'Lys-11'-linked ubiquitin chains.  Cleaves both polyubiquitin and di-ubiquitin.  May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.  May recruit PLAA, UBXN6 and VCP to damaged lysosome membranes decorated with K48-linked ubiquitin chains and remove these chains allowing autophagosome formation.
What are the official names of this protein?
Ubiquitin thioesterase OTU1.
What are the subcellular locations of this protein?
Cytoplasm. Note=Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains.
Protein: RL2_CUPMC
Sequence: MALVKTKPTSPGRRSMVKVVNKDLHKGAPHAPLLEKQFQKSGRNNNGHITTRHKGGGHKHHYRVVDFKRNDKDGIAAKVERLEYDPNRSANIALVLFADGERRYIIATKGMVAGQALMNGSEAPIKAGNNLPIRNIPVGTTINNVEILPGKGAQVARAAGGSAVLLAREGLYAQVRLRSGEVRRVHIECRATIGEVGNEEHSLRVIGKAGATRWRGIRPTVRGVVMNPVDHPHGGGEGKTAAGRDPVSPWGTPAKGYRTRSNKRTDSMIVQRRHKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.