PharMolix/UniProtQA huggingface dataset:
Protein: CHBG_SERMA
Sequence: MEKLLIVNADDFGLSKGQNYGVIEAYQHGVVSSTTAMVNGGGAQHAAALSRQYPGLPIGLHFVLTHGKPLGAMPSLVNEHGELGKWLWRRAEAGELSLDEIHEELQRQFARFVTLFGRPPTHIDSHHHVHMQPQIYPLVEAFAQAQGLPLRLDREEAKRRELALQTPCSTDAFDAGFYGEMISEALFLQRLARADEQGAESLEMMCHPAFLDATILQSKYCHPRLVELDVLTAPTLKAAIAERGFLLGSFQDL
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_ANADF
Sequence: MNRTEKEQVIGELHEKMAMAKAAILAEPKGLNVATVTELRRKLREAKVEYRIVKNTLAARAAKGTPVESIAEKFVGPTALVMSYDDVVTPAKLLADFMKDRENFTIRTAVIEGRVVDAKGIQSLAKMPGLQELRGQIAAMIAQPATQLARVLGAPGQQLARVLGARREQLEKQS
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SECA2_RUEPO
Sequence: MSDTFPGQAPGAFYPRAPAEPAKSKLDRWIEKYTTLPRRRRRARPSRFFAWRVLRRGKAFAQMSDDRLQGEVRAAAYGMRAARAHPGEALLVRSFALIRECAGRELGQRHYATQILGARAVLNGAVAEMQTGEGKTLAITLAAGTAALAGRRVHVITANDYLAGRDADTMRGLYARLGLTCAAVEPGCTPEERRAAFAADIVYASGKEVAFTFLRDRVAMGGRAGDIGLRTRAFFDGTGLLLPGLQFAIVDEIDSVMIDEARTPLILSVPPADAEVEAEAARAAHAIAAELKEGRDYRLDRLRHAVELSRNGCDRLADLAERMPPAWRPAPIREDAVRTAISAIRLHQRDEHYILRDGKVEIVDEFTGRIMPDRSWSAGLHQAVEAKEGVEITSRRVTLAQITFQRFFRRYIHLGGMTGTATEAADEFWSVYDLPVVRIPTHKRSRRRTWKTQVSTRAATKWARVAKRAKALSASGRPVLIGTRTVAASEAASAALHALGVPHRVLSAAQDADEAAVVAEAGRAGAVTVATNMAGRGTDIILDAEARKAGGLHVIMTEKHSSRRIDRQLAGRAGRQGDPGSTEAILSAEDSLLPEFGGRYSSFVTRFGGSAVLSALTDAQRRAERTHVAARRRLLELDEQMAENLAFTGTPE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: TRPB_ALTMD
Sequence: MNQLDTKFGEFGGMYVPELLIPALDQLEKAFLDAKEDPSFNEEFLSLLKDYAGRPTAMTLTRNLVSNPKVKLYLKREDLLHGGAHKTNQVLGQALLTKRMGKKEVIAETGAGQHGVATALACALLGLKARIYMGAKDVERQAPNVFRMKLMGAEVIPVNAGSGTLKDAVNEAMRDWSANYDTAHYLLGTAAGPHPFPTIVREYHRMIGEETRAQIMEKEGRLPDAVVACVGGGSNAIGMFADFIDEPSVRLVGVEPAGKGVHTKEHGATIVTGTKGILHGAYTFIMQDKEGQIEESYSVSAGLDYPAVGPQHAYLHDIGRAEYVAATDEEALNAFQLLARKEGIIPALESSHALAHALNMADEAEEETIIVVNLSGRGDKDLAHVINILGDDL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: TIP41_MAIZE
Sequence: MAKLMNKLVDSFEHDEIPDVGCVRAVLAELVLTFLFVFTGVSAAMAAGSDGKPGDAMPMATLAAVAIAHALAAGVLVTAGFHVSGGHLNPAVTVGLMVRGHITKLRAVLYVAAQLLASSAACVLLRFLSGGMVTPVHALGRGISPMQGLVMEVILTFSLLFVTYAMILDPRSQVRAIGPLLTGLIVGANSLAGGNFTGASMNPARSFGPALATGDWTNHWVYWIGPLLGGPLAGFVYESLFLVQKMHEPLLNGEV
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin TIP4-1, Tonoplast intrinsic protein 4-1, ZmTIP4-1, ZmTIP4;1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. TIP (TC 1.A.8.10) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: ERA_HAEIG
Sequence: MTEQFDKTYCGFIAIVGRPNVGKSTLLNKILGQKISITSRKAQTTRHRIVGIKTEGAYQEIYVDTPGLHIEEKRAINRLMNRAASSAIGDVDLIIFVVDGTHWNADDEMVLNKLRNAKAPVVLAINKVDNIKNKDDLLPFITDLSSKFNFAHIVPISAQRGNNVHELEKIVRQSLREGVHHFPEDYVTDRSQRFMASEIIREKLMRFTGEELPYSVTVEIEQFKVNERGTYEINGLILVEREGQKKMVIGAGGQKIKTIGMEARADMERLFDNKVHLELWVKVKSGWADDERALRSLGYMDE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: P5CS_SOLLC
Sequence: METVDSTRAFVKNVKRLIVKVGTAVVTRADGRLALGRLGALCEQLQELNSQGYEVILVTSGAVGVGRQRLRYRKLLNSSFLDLQKPQTELDGKACAAVGQNGLMALYDSLFSQLDVTSAQLLVTDNDFRDPDFRRQLNDTVNSLLSLKVIPIFNENDAISTRRAPYEDSSGIFWDNDSLAALLALELKADLLVLLSDVDGLYSGPPRDPDSKLIYTYIKEIHERVITFGDKSRVGRGGMTAKVKAAMYAAYAGIPVVITSGFATDNIIKVLHGERIGTLFHCDANKWASIGETDAREMAVAARACSRRLQALSSQERSKILQDIADALEANEKAILAENEADVVAAQQAGYEKSLISRLALNPGKISSLANSVRVLSNMDEPLGHTLKRTEIADGFILEKSSSPLGVVLIIFESRPDALVQIASLAVRSGNGLMLKGGKEAKRSNAILHKVITSAIPVSVGERLIGLVTSREEIPELLKLDDVIDLVIPRGSNKLVSQIKASTKIPVLGHADGICHVYVDKSADMDMAKRITVDAKIDYPAACNAMETLLVHKDLAQNGGLNDLIVELQTKGVSLYGGPKASSLLMIPEARTFRHEYSSLACTVEVVEDVYAAIDHIHQHGSAHTDSIITEDQEVAEVFLRQVDSAAVFHNASTRFSDGFRFGLGAEVGISTGRIHARGPVGVEGLLTTKWLARGSGQIVDGDKSIVYSHKDLTQQG
What is the function of this protein?
P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants.
What are the official names of this protein?
Delta-1-pyrroline-5-carboxylate synthase, P5CS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
Protein: RL20_THEFY
Sequence: MARVKRSLNAKKKRRVVLSQAKGYRGQRSRLYRKAKEQMLHSMTYAYRDRKDRKGQFRRLWIQRINAASRAHGLTYNRFMQGLKAAGIEVDRRMLAELAVNDAAAFAALVETAKKAIPAPSESAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TDH_SINMW
Sequence: MTNMMRALVKTRPEVGLWMERVPVPEVGPNDVLIRVRKSAICGTDVHIWNWDQWAQKTIPVPMVVGHEFMGEIVEVGPAVTKHHVGERVSGEGHIVCGKCRNCRAGRGHLCRNTLGVGVNRPGSFAEFVCLPEYNVVSIPDDVPDEIAAIFDPFGNAVHTALSFDLVGEDVLVTGAGPIGIMGALVAKRCGARKVVITDINPVRLDLARKVGIDYVVDASKENLADVMRVIGMTEGFDVGLEMSGAAPAFRDMIDKMNNGGKIAILGIAPAGFEIDWNKVIFKMLNLKGIYGREMFETWYKMIAFVQGGLDLSQIITHRIGIDEFGDGFEAMRSGNSGKVVMDW
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_RICTY
Sequence: MNVFLSKYINGVDKKSRVTVPANYRAVLGKELFNGVIAYPSIRNNCIEVCGIAHIEKLRKMIETLDPYSEERDAFETMIFGEAVQLAFDGEGRIILPQSLMKHADIEEQACFVGKGIIFEIWQPQNFEKYLSYAQNIAHEKRLTLRNVH
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL35_MYCSK
Sequence: MPKAKTHSGASKRFRRTGTGKIVRQKANRRHLMEHKPTKRTRRLAGRTQVSANDAPRINKMLNG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: TTCA_ALKEH
Sequence: MMGSAQTLATRHAPNPRGLVMGMGLKTLQKRLSHLTGNAIRDYRMIEEGDRVMVCLSGGKDSYALLDVLLRLQKRAPVRFELVAVNLDQKQPGFPEHVLPEYLASLGVPYRILEADTYSTVERVIPEGKTKCSLCSRLRRGLLYGAAEEMGCSKIALGHHRDDILETFFLNLFYGGRLAAMPPKLRSNNGRHVVIRPLAYVPEPYLERYAERMAFPIIPCTLCGSQPDLKRQMIKAMLREWGEIEPRRLANIFSALQNVQPSHLADKELYDFINLVGSVQPGEDPVSALETPHGDGFPAAEVLSGVQRHDPQSA
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCTL1_SALTY
Sequence: MLKNIPIPSPLSPVEGILIKRKTLERYFSIERLEQQAHQRAKRILREAEEEAKTLRMYAYQEGYEQGMIDALQQVAAYLTDNQTMAWKWMEKIQIYARELFSAAVDHPETLLTVLDEWLRDFDKPEGQLFLTLPVNAKKDHQKLMVLLMENWPGTFNLKYHQEQRFIMSCGDQIAEFSPEQFVETAVGVIKHHLDELPQDCRTISDNAINALIDEWKTKTQAEVIR
What is the function of this protein?
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:28283062).  Acts as a regulator of the InvC/SctN1 ATPase activity (By similarity).  Required for invasion and secretion (PubMed:10816487).
What are the official names of this protein?
SPI-1 type 3 secretion system stator protein, T3SS-1 stator protein, Oxygen-regulated invasion protein OrgB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_LEPIN
Sequence: MQESGLKPILWKNKELILLDQRVLPGTTSYITAKTLEDCIFAIREMVVRGAPAIAITGAFGITLYWNSLVSKPSFSELKLKLSELLESRPTAVNLRLAIEEFSSRFPESNYSSFSLEEIQKGAEELALFMLSEDLENNLTLSKYALSLFPKQPSSLNIITHCNTGALATAGHGTALGVIRSLRDAGHSLTVFADETRPYLQGARLTAWELQEEKIQSFLITDNMAGWVMSSRKIDAVIVGADRIASNGDTANKIGTYPLAIVAKHHGVPFYVAATAKSMDFRIPNGSYIPIEMRKEEEITSFGFLKDSDGKPLLKEGVIAPKGMKALNPSFDVTPASLITGIITEKGIVSPVTEENLKKIFQLI
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: PANB_PYRNV
Sequence: MPRKSVLDFAKGRGAYVWITAYDYPTAKAVDEAGVDGILVGDSLGMVLLGLPNTLGVTMEDMVRHTEAVARARPRALVVADMPFMSYETGPEDALRNAARLVKAGADAVKLEGGTEYAPIVERLVKAGIPVMGHIGLTPQRFLTIGGFKMVGKTEEQRRKILEDAKALRDAGVFSIVLEFVPASLAREVTQAVDVPTICIGSGPHCDGQILVLHDVVGLTERPPSFAKKYADVAAAIREAVSKYAEEVRKGLFPAREHYRE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_LACE2
Sequence: MKMTFQPKNRQRSKVHGFRSRMSTAGGRKVLSARRAKGRKKLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: EPSD_RALSL
Sequence: MDRAIEIDFRTISVVGLGYIGLPTATVLASRQRELIGVDINQHAVDTINQARIHIVEPDLDMLVRAAVSQGYLRATTEPEPADAFLIAVPTPFLEDKQPDLTYIEAAAKAIAPVLKRGDLVVLESTSPVGATEQLSAWLSEQRSDLSFPHQLGEESDIRVAHCPERVLPGHVLRELVENDRIIGGMTPRCSQAAQRLYELFVRGRCIVTDARTAEMCKLTENAFRDVNIAFANELSMICDEIGVNVWELISVANRHPRVNILQPGPGVGGHCIAVDPWFIVDAAPESARLIRTAREVNDAKPHYVLDRVKQAARRFKEPVIACFGLSFKANIDDLRESPAIEIVRTMVQQQLGTVLVVEPHIKVLPASLEGVELLNAEPALSRADIVVLLVDHQKFRKLDTDRLQSRVVIDTRGMWSAKRLAA
What is the function of this protein?
Probably involved in synthesis of sugar components of EPS I, by converting NDP-N-acetyl-D-galactosamine into NDP-N-acetyl-D-galactosaminuronic acid.
What are the official names of this protein?
NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: RK16_OENBI
Sequence: MLSPKRTRFRKQHRGRMRGISYRGNRICFGKYALQALEPAWITSRQIEAGRRAMTRNVRRGGKTWVRIFPDKPVTLRAAETRMGSGKGNPEYWVAVVKPGRILYEMGGVAENIARKAISIAASKMPIRTQFIISG
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HES1_CHICK
Sequence: MPADTGMEKPTASPIAGAPASASHTPDKPRSASEHRKSSKPIMEKRRRARINESLGQLKMLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMAAALSADPSVLGKYRAGFNECMNEVTRFLSTCEGVNADVRARLLGHLSACLGQIVAMNYLPPPPAGQPAHLAQPLHVQLPPTTTGAVPVPCKLEPTEALSPKVYGGFQLVPATDGQFAFLIPNPAFPPGSGPVIPLYANANVPVSTAWRSSERVHPPAGIPGAGLDIIWARVVPASQAGSPIAERREAVWRPW
What is the function of this protein?
Transcriptional repressor of genes that require a bHLH protein for their transcription.  May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity).
What are the official names of this protein?
Transcription factor HES-1, C-HAIRY1, Hairy and enhancer of split 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR3_COFAR
Sequence: MGQKINPLGFRLGTTQGHHSLWFTQAKNYSEGLQEDQQIRNCIKNYVQKNTKISSGVEGIARIEIQKRIDLIQVIIFMGFPKPLLENQPRGIEELQTNLQKKCNSVNRKFNIAITKIAKPYGNPNILAEYIAGQLKNRVSFRKAMKKAIELTEQANTKGIQVQIAGRIDGKEIARVEWIRRGRVPLQTIRAKIDYCSYTVRTIYGVLGIKIWIFIDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: T2AG_SCHMA
Sequence: MTYHEMYRSTTLGTTLREALDEMLAHNLLQPGMDHKVMQKFDQCISNALAKRVKNRLSLRGHLNTYRNCDNVWTLVMNDVEIKDSSAIMTVDKVSLNSPLICKI
What is the function of this protein?
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.  TFIIA in a complex with TBP mediates transcriptional activity (By similarity).
What are the official names of this protein?
Transcription initiation factor IIA subunit 2, General transcription factor IIA subunit 2, Transcription initiation factor IIA gamma chain, TFIIA-gamma.
What is the protein family that this protein belongs to?
Belongs to the TFIIA subunit 2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RING1_CANLF
Sequence: MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPMPGSDQTTTMSGGEGEPGEGEGDGEDVSSDSAPDSAPGPAPKRPRGGGAGGSSVGTGGGGAGGVGGGAGSEDSGDRGGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQEAGEPGGPGGGASDAGGPDGGGGEGGGTRGGDGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK
What is the function of this protein?
Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation.  H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.  Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility.  Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RING1, Polycomb complex protein RING1, RING finger protein 1, RING-type E3 ubiquitin transferase RING1, RING1a.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: BXB10_BOMMO
Sequence: MKTILIFLVVISLMYSGEAQEVAHTYCGRHLADTLADLCFGVEKRSGAQYAPYFWTRQYLGSRGKRSVVDECCFRPCTLDVLLSYCD
What is the function of this protein?
Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects.
What are the official names of this protein?
Bombyxin B-10, BBX-B10, 4K-prothoracicotropic hormone, 4K-PTTH.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: KAD_THENN
Sequence: MMAYLVFLGPPGAGKGTYAKRIQEKTGIPHISTGDIFRDIVKKENDELGKKIKEIMEKGELVPDELVNEVVKRRLSEKDCEKGFILDGYPRTVAQAEFLDSFLESQNKQLTAAVLFDVPEDVVVQRLTSRRICPKCGRIYNMISLPPKEDELCDDCKVKLVQRDDDKEETVRHRYKVYLEKTQPVIDYYGKKGILKRVDGTIGIDNVVAEVLKIIGWSDK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAD3_HUMAN
Sequence: MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELLRGFVAGQEHSYSHGGGAWL
What is the function of this protein?
Transcriptional repressor.  Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'.  Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity).
What are the official names of this protein?
Max dimerization protein 3, Max dimerizer 3, Class C basic helix-loop-helix protein 13, bHLHc13, Max-associated protein 3, Max-interacting transcriptional repressor MAD3, Myx.
What are the subcellular locations of this protein?
Nucleus.
Protein: VL2_HPV18
Sequence: MVSHRAARRKRASVTDLYKTCKQSGTCPPDVVPKVEGTTLADKILQWSSLGIFLGGLGIGTGSGTGGRTGYIPLGGRSNTVVDVGPTRPPVVIEPVGPTDPSIVTLIEDSSVVTSGAPRPTFTGTSGFDITSAGTTTPAVLDITPSSTSVSISTTNFTNPAFSDPSIIEVPQTGEVAGNVFVGTPTSGTHGYEEIPLQTFASSGTGEEPISSTPLPTVRRVAGPRLYSRAYQQVSVANPEFLTRPSSLITYDNPAFEPVDTTLTFDPRSDVPDSDFMDIIRLHRPALTSRRGTVRFSRLGQRATMFTRSGTQIGARVHFYHDISPIAPSPEYIELQPLVSATEDNDLFDIYADDMDPAVPVPSRSTTSFAFFKYSPTISSASSYSNVTVPLTSSWDVPVYTGPDITLPSTTSVWPIVSPTAPASTQYIGIHGTHYYLWPLYYFIPKKRKRVPYFFADGFVAA
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: TATA_HAES1
Sequence: MGLSWQQLLILLLVVVVIFGTKKLRNIGSDLGGAVKDFKKAMNDDQPKDAEFKKISEEVEQTSVENSKQKEQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LUXO_VIBPA
Sequence: MVEDTASVAALYRSYLTPLGIDINIVGTGRDAIESLNHRIPDLILLDLRLPDMTGMDVLHAVKKSHPDVPIIFMTAHGSIDTAVEAMRHGSQDFLIKPCEADRLRVTVNNAIRKATKLKNEADNPGNQNYQGFIGSSQTMQQVYRTIDSAASSKASIFITGESGTGKEVCAEAIHAASKRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAANDRQGAAELADGGTLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRERGEDVIEIAYSLLGYMSHEEGKNFVRFSQEVIDRFNSYEWPGNVRQLQNVLRNIVVLNNGKEITLDMLPPPLNQPLDRPSVSKLIEPKAMTVSEIMPLWMTEKMAIEQAIEACDGNIPRAAGYLDVSPSTIYRKLQAWNGKEERQKV
What is the function of this protein?
Involved in the regulation of different processes depending on the cell density.  Acts together with sigma-54 to repress, perhaps indirectly, some genes (By similarity).
What are the official names of this protein?
Regulatory protein LuxO.
Protein: SYN_LACGA
Sequence: MTELISIKDSSKHVDQKVKMHVWLTDKRSSGKIIFLQLRDGTAFFQGVVRKNDVSEEVFEAAKSLRQEASFYITGTVHEDKRSHFGYEIQISDLEIVSNNEGYPIGNKEHGVDFLLDNRHLWLRSKRPFAIMQIRNTMFKATVDFFEKEGFIKFDAPIFMHSAPEGTTQLFHVEYFNNDAYLSQSGQLYGEAGAMAYGKIFTFGPTFRAEESKGRRHMTEFWMMEPEMAWMHQDESLDIQERYLAYMVKQVLENNEYELRILGRDPEKLRPTTEGNFTRLPYDDAIKMLQEAGRDIKWGDDFGAPDEGYISEQFDRPVFIVNYPTTIKPFYMKKNPDNPKEYLCADVIAPEGYGEIFGGSEREGNYEILKKQIEEAGLNLEDYQWYLDLRKFGGVPHSGFGMGFERTIAWICKLDHIREAIPFPRLINRMQP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.