PharMolix/UniProtQA huggingface dataset:
Protein: UBIE_CUPMC
Sequence: MSETHFGFEKVDESEKAGKVAGVFHSVASKYDVMNDLMSGGMHRLWKVFTIAQANVRPGQKVLDIAGGTGDLAKAFAKQAGPTGEVWLTDINESMLRVGRDRLLNKGVVTPVALCDAERIPFPDNYFDLVTVAFGLRNMTHKDAALAEMRRVIKPGGKVMVLEFSKVWKPLEKFYDVYSFKVLPWLGERVAGDAPSYRYLAESIRMHPDQGSLVRMMEQVGLEQVEYFNLTAGVVALHVGRKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: MURC_BUCAI
Sequence: MNIKDIKKINFFISEKKNKNIHLIGIGGAGMMGIALILLKLGYKVSGSDLLESLMIKKLINLGATIYLQHSEKNIKNVDFIIKSSAISSNNKEILAAKKRNIPILLRAEMIEILMSFKKGIAVSGTHGKTTTTSMIADIFIDSGLDPTVINGGLIKSINSYAKLGSSSYFITEADESDASFLYLNPNIIIVTNIEPDHIDHYDNSFKKLKQTFLIFLKKITLYGTAIVCIDNNAICDILTNLKCKIITYGFNKNADVRIFLYKQNNFIGHFYIILKNNKKLNIILNIPGKHNALNAAAAIALAIHEGINNDLMIASLKNFQGTCRRFEFLGFLSIDQGFDKRANCMLIDDYGHHPTELSETIKTIRISWPNKNLIMIFQPHRYTRTYNLYHDFVQTLSQVDVLLILHVYSANEKFIVGADSLSLFNDIKKLGKNYVTLISNHNMILDTLIQTLQGNDIILIQGAGNIDTIAHKILIKKTKKVIK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP1_THEKO
Sequence: MLHLIIAEAELELVPESIRDHPAVVNYARRRKKRPEEAILDSTYHHAALKKLPDGDRRGRPDIVHICLLNALESIANKEGFLRVYVHTRNDEVIHIKPETRLPRNYNRFLGLMESLFKKGAVPEGLELLRIEKKPLESLIEDINPDTVFIMHEEGELIRPRSFGEILASHQNPVVVVGGFPHGDFMRPIEGTKVSLYREPLMAWTVVSEVIVNFEAALGL
What is the function of this protein?
Methyltransferase involved in ribosomal biogenesis.  Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase Nep1, 16S rRNA (pseudouridine-N1-)-methyltransferase Nep1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Protein: AROD_SHIDY
Sequence: MKTVTVKDLVIGAGAPKIIVSLMAKDIARVKSEALAYRETDFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRILLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: FABG_SALTI
Sequence: MSFEGKIALVTGASRGIGRAIAETLVARGAKVIGTATSENGAKNISDYLGANGKGLMLNVTDPASIESVLENIRAEFGEVDILVNNAGITRDNLLMRMKDDEWNDIIETNLSSVFRLSKAVMRAMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIASAVAFLASDEASYITGETLHVNGGMYMV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase FabG, 3-ketoacyl-acyl carrier protein reductase, Beta-Ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SARA_SALT1
Sequence: MMRFVYIYILVIYGSYLWFSLGGNMFTINSTNRVASTIAPYACVSDVNLEDKATFLDEHTSIHANDSSLQCFVLNDQHVPQNTLATDVEGYNRGLQERISLEYQPLESIVFLLGTPAVLETKESLSLPVSPDALTQKLLSISSNDECKLSGSTSCTTPASHNPPSGYIAQYRHSAEVFPDE
What is the function of this protein?
A Salmonella strain-specific effector that induces a host STAT3-dependent anti-inflammatory pathway.  In bacteria-infected host cells (human) leads to phosphorylation of host STAT3, at least on 'Tyr-705' and interleukin-10 (IL-10, IL10) production; expressing the gene alone in host cells induces STAT3 phosphorylation and IL-10 production.  IL-10 production requires STAT3 in infected cells.  Contributes to virulence in mouse infection models (PubMed:29924996).  Encoded in only a few S. typhimurium serovars, it may be a specific effector for adaptation to bovine hosts (Probable).
What are the official names of this protein?
Salmonella anti-inflammatory response activator, SarA, Salmonella translocated effector E.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Host cytoplasm. Note=Secreted mainly by the SPI-2 type III secretion system (T3SS), with a minor contribution from the SPI-1 T3SS.
Protein: PROB_METPP
Sequence: MSEVLRGARRIVVKVGSSLVTNEGRGVDAAAIGNWCRQLASLAGQGREVLMVSSGAIAEGMKRLGWNARPKEIHELQAAAAVGQMGLAQMYESKLSEHGIGSAQVLLTHADLADRERYLNARSTLLTLLSLKVIPVINENDTVVNDEIKFGDNDTLGALVANLVDADALVILTDQPGLYSADPRKDPQARFIGEAVAGTPELERMAGGAGSSLGRGGMITKVLAAKRASSSGASTVIAWGREPDVLLRLADGEAIGTLLVARTAKLAARKQWMADHLQMRGTVVIDDGAVAKLRDEGKSLLPIGVVEVQGEFVRGDVIAVRSQVGIEIARGLANYASSEARLIARKPSSQIESLLGYSNEPEMIHRTNLVLA
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBE2K_MOUSE
Sequence: MANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLSN
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains.  Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein.  Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins.  Ubiquitinates huntingtin.  May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53.  Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B; in vitro supports ubiquitination of NFKB1.  Involved in stabilization of CASP12 during ER stress-mediated amyloid-beta neurotoxicity probably by inhibiting proteasome activity; in vitro ubiquitinates CASP12.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 K, E2 ubiquitin-conjugating enzyme K, Huntingtin-interacting protein 2, HIP-2, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-protein ligase.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_BEII9
Sequence: MAVDRPQNLQDTFLNFVRKNKVPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKHAISTIMPGAPIQMFEPGDEAGHAG
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: IL15_CHLAE
Sequence: MRISKPHLRSISIQCYLCLLLKSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISHESGDTDIHDTVENLIILANNILSSNGNITESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
What is the function of this protein?
Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems.  Stimulates the proliferation of natural killer cells, T-cells and B-cells and promotes the secretion of several cytokines.  In monocytes, induces the production of IL8 and monocyte chemotactic protein 1/CCL2, two chemokines that attract neutrophils and monocytes respectively to sites of infection.  Unlike most cytokines, which are secreted in soluble form, IL15 is expressed in association with its high affinity IL15RA on the surface of IL15-producing cells and delivers signals to target cells that express IL2RB and IL2RG receptor subunits.  Binding to its receptor triggers the phosphorylation of JAK1 and JAK3 and the recruitment and subsequent phosphorylation of signal transducer and activator of transcription-3/STAT3 and STAT5 (By similarity).  In mast cells, induces the rapid tyrosine phosphorylation of STAT6 and thereby controls mast cell survival and release of cytokines such as IL4 (By similarity).
What are the official names of this protein?
Interleukin-15, IL-15.
What is the protein family that this protein belongs to?
Belongs to the IL-15/IL-21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPB_VIBVY
Sequence: MVRIAVAGAAGRMGRNLVKAAHHNPAAKVAAGSERPESSLVGVDLGELCGECKFDVVVCDDLAKQIDQFDVIIDFTAPASTLNNLALCQQYGKSIVIGTTGFTEEQREQIDLVAQQVPVVMAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIVEAHHRHKVDAPSGTAIGMGEAIAGAMGNKLSDVAVYAREGITGERTKDEIGFATIRAGDIVGEHTAMFADIGERVEITHKATDRMTFANGAVKAAVWLHEKPAGFYTMTDVLGLNDL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y118_NPVAC
Sequence: MHFTYWRMSEYFCTYEIFAANAIMCALMPCLAIFFIIELLCKNFNTMYNVMYVVLFAIFQLFEKGFDIAKTIADKWHIRKILLFVNNAYQHLTLYVEKYQSINYAIKIAAIYYNIYVLYYSVVFLHCLLFFNVHSKIIIKLFVVLGIDVALYSLIIK
What are the official names of this protein?
Uncharacterized 18.7 kDa protein in HE65-PK2 intergenic region.
Protein: ENGB_STRZP
Sequence: MELNIHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINTMLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYLTTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESAIKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SYT_BUCBP
Sequence: MPTIKFIDGTCRVYPGSISVLDILKDVSPNSVQDFMFGCVNGISVDRNAIVTNDSIVKFVYKTDQSTLDIIRYSCICLLGKAVKKLWPSSKIGESDVLENGFFCDIEVDFSFNETSLHLLEACMRQMINKKYKIYTKTFSLKKASTIFKNRNETYKLFLLDRLVNFSNQVVSLCFHEEYIDIQKKISVPNIFLCRNFRLQKFSGVYWKGKRENKVLQRIYGTSWITRIQLEKHLDNVKKLDSRDHRKISKILDLYHIQEDLPGMIFWHRNGWIVFQELKKLIRVKLRKYNYQEVKTPVMMNKKIWKDSGHLDNYKESMFMVCSSNFEYGIKPMNCPGHVQIFNHVVRSYRDLPIRISEFGSCHRNEPSGALHGLMRIRNFTQDDAHIFCREDQICSEVSNCIRMVYEIYKIFGFKKILVRLSTRPKNRIGNDNIWDKAENDLATSLRESKIEFEYQHGEGAFYGPKIELSLFDSLGRVWQCATIQLDFCLPINLKAFYIDHNNERKVPIIVHRAVLGSIERFIGILIEEYIGNFPTWLAPIQVVLANVNSNHLQYIKLLYKEFYALGIRSEIDSRNETISYKIREHIARKIPYIIICGDKEVKNNTITLRTRSGKNFYCIDVQFFISKLCKEINSYSCSLMEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y164_IDILO
Sequence: MGRAYQNRKDSIAKTANAKSKVYSRYGREIYVCAKQGGGDPDGNLALRGLIDRAKKDQVPAHVIEKAIDKAQGGAGEDFSPARYEGYGPSNCMVIVECLTDNPNRTFGDVRNCFTKSKSKIGAQGSVAHSFDHCAIFAFRHDNEDEVLEAMMEADVDVTDVEFEDGLVTVFAPNTEYAAARQALTHAFPDIDFEADEIQFLPQVTTSIAEDDLPMFERLMDMLNDLDDVQNIYHNAEH
What are the official names of this protein?
Probable transcriptional regulatory protein IL0164.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTM1_ASPOR
Sequence: MSEGSNSTSAAASTQRQVRVQLTSKQEDIALPENTGPILVPTGLRRYALSTLVNNLLGNDKPIPFEFLINGSFLRTSIDEYLTANGISAETTLEIEYVRALIPPLHIASFEHDDWVSSVDVLSTTSPAASLASATIAAGQERILSGSYDGLLRVWNMSSQIVATSPSAADGGHTASIKAAKFISPNSIVSAGLDRTVRVWKYSEDGDGFSGKIAPQLELYGHKGPINSLSVHAPSNRILSASSDHSIGFWSTKKSDAPAAPEDLLPSAALRSSKRRKLNSSVTIPQRGPLALLSSHSAPVSAAIFDSNDSTVGYSASWDHSLRTWDLVTATLVDTRTTSHSLLSLEHLPEHHLLAAGTSARHITLIDPRVSATTIAAMTLRGHTNAVVSLARDPKSSYGLISGSHDGTCRIWDIRATKTDKDGVVGESVYSISRKSLEEQGKSEAKRIGGEGVKVFGVAWDGTVGIVSAGEDKRIQINRGEGVLSSA
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ytm1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: CUTC_AGRFC
Sequence: MKEVPMILEICVDDVAGLEAAVRGGADRIELCAALSGGGVTPSAGFMQRAATYGLPVSVMIRPRAGDFVFTHDEADVMKRDIDAARAAGLSGVVLGASRGDGSLDMALLEDLRRHADGMDATLHRAFDVAPDMEEALEAAISLGFPRILTSGGARSALEGVKTLARLSELAKGRIVIMPGAGVRPQSVQALLDSFPITEIHASCSAVPLYDPESRVAKLGFTGAGRKATDEAAVRELKTILSAHHKGGATL
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4HYPE_PSYCK
Sequence: MASSLFNFKIIDSHTGGEPTRMVYDGFPDLVGDTIQDKLQSFKQNFDHLRQSIILEPRGNDVLVGALLLPASHPKATAGVIFFNNAGYLGMCGHGTIGVIVSLAYQQKISAGVHWLETPVGLVKATLHDDGSCSVQNVPSYRYKKQVEVHVPELGLIRGDIAWGGNWFFLVSEHGQDIQASNVKQLTQVTMQIKQALVAANITGENSSEIDHIELFADSDDTQVDSKNFVLCPGSAYDRSPCGTGTSAKLACLAADNKLAPEQLWQQQGVVGSVFTGSYQYASELNTTLKNPAGAAYPEQTIIPTICGHAYVCAETTLIMQEDDPFKWGIPS
What is the function of this protein?
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp).  Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate.  Displays no proline racemase activity.
What are the official names of this protein?
4-hydroxyproline 2-epimerase, 4Hyp 2-epimerase, 4HypE.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: NS1A_HASV8
Sequence: MMALGEPYYSSKPDKDFNFGSTMARRQMTPTMVTKLPKFVRNSPQAYDWIVRGLIFPTTGKTYFQRVVVITGGLEDGTYGSYAFNGSEWVEIYPIEHLNLMSSLKLIHKANALQERLRLSQEEKATLALDVQFLQHENVRLKELIPKPEPRKIQMKWIIVGAVLTFLSLIPGGYAQSQTNNTIFTDMIAACKYSTETLTENLDLRIKLALANITINDKLDAVRQILNFAFVPRAHWLRTVFYYIHYYEMWNIFMFVLAIGTVMRSARPGTDLITLATSHLSGFRMAVLPTIPFHTTMTLWVMNTLMVCYYFDNLLAITMAILAPILGIIFLCFMEDSNYVSQIRGLIATAVLIAGGHACLTLTGTTTSLFVVILTCRFIRMATVFIGTRFEIRDANGKVVATVPTRIKNVAFDFFQKLKQSGVRVGVNDFVVIKPGALCIIDTPEGKGTGFFSGNDIVTAAHVVGNNTFVSVCYEGLVYEAKVRYMPEKDIAFITCPGDLHPTARLKLSKNPDYSCVTVMAYVNEDLVVSTATAMVHGNTLSYAVRTQDGMSGAPVCDKYGRVLAVHQTNTGYTGGAVIIDPADFHPVKAPSQVELLKEEIERLKAQLNSAAENPVTVVTQQPIVTLEQKSVSDSDVVDLVRTAMEREMKVLRDEINGILAPFLQKKKGKTKHGRGRVRRNLRKGVKLLTEEEYRELLEKGLDRETFLDLIDRIIGERSGYPDYDDEDYYDEDDDGWGMVGDDVEFDYTEVINFDQAKPTPAPRTTKPKPCPEPKIEAQPLDLSQKKEKQPEHEQQVAKPTKPQKIEPQPYSQTYGKAPIWESYDFDWDEDDAKFILPAPHRLTKADEIVLGSKIVKLRTIIETAIKTQNYSALPEAVFELDKAAYEAGLEGFLQRVKSKNKAPKNYKGPQKTKGPKTTTH
What is the function of this protein?
Protein covalently attached to the 5' extremity of the genomic and subgenomic RNAs.
What are the official names of this protein?
Non-structural polyprotein 1A.
What is the protein family that this protein belongs to?
Belongs to the astroviridae polyprotein 1A family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: DER_STRZT
Sequence: MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: OCE4_LEPPU
Sequence: MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKGAGKQLIAHAMGKIAEKV
What is the function of this protein?
Has antibacterial activity against Gram-negative bacteria E. coli ATCC 25922 (MIC=80 uM), K. pneumoniae ATCC 700603 (MIC=310 uM) and S. choleraesuis ATCC 14028 (MIC=310 uM).  Shows no hemolytic activity and no cytotoxicity.
What are the official names of this protein?
Ocellatin-PT4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ocellatin subfamily.
Protein: HSLO_BACC4
Sequence: MKDYLVKALAFDGEVRAYSVRTTNTVSEAQRRHDTWRTASAALGRSLTAGTMMGAMLKGEQKLTIKVEGNGPIGPILVDAHANGDVRGYVTNPHVDFEGTEQGKLRVYQAVGTEGFVTVIKDIGMREPFIGQSPIVSGELGEDFTYYFAVSEQTPSSVGVGVLVNGDDSILAAGGFILQIMPGAQDETISFIEDRLQKIPPVSTLIEQGLSPEELLYAVLGEDKVKVLETMDVQFNCTCSRERIESVLISLGKTELEQVREEEEETEVHCHFCNERYKFSKEDITNLIENL
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCNA_SALPA
Sequence: MGEFPTLLQQGNGWFFIPSAILLGILHGLEPGHSKTMMAAFIIAIKGTVKQAVMLGLAATLSHTAIVWLIALGGMYLSRAFTAQSVEPWLQLISAIIILSTACWMFWRTWRGEQQWLAGNHHHDHDHDHDHDHDHHGHIHPEGATSKAYQDAHERAHAADIQRRFDGQTVTNGQILLFGLTGGLIPCPAAITVLLICIQLKAFTLGATMVLSFSLSLALTLVTVGVGAAISVQQAAKRWSGFSTLARRAPYFSSILIGLVGVYMGIHGYTGIMQ
What is the function of this protein?
Efflux system for nickel and cobalt.
What are the official names of this protein?
Nickel/cobalt efflux system RcnA.
What is the protein family that this protein belongs to?
Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MET14_PONAB
Sequence: MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLNSKDEQREIAETRETCRASYDTSAPNAKRKYLDEGETDEDKMEEYKDELEMQQDEENLPYEEEIYKDSSTFLKGTQSLNPHNDYCQHFVDTGHRPQNFIRDVGLADRFEEYPKLRELIRLKDELIAKSNTPPMYLQADIEAFDIRELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEGLDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRSTDGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNYNAETYASYFSAPNSYLTGCTEEIERLRPKSPPPKSKSDRGGGAPRGGGRGGTSAGRGRERNRSNFRGERGGFRGGRGGAHRGGFPPR
What is the function of this protein?
The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis.  In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core.  N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing (By similarity).  M6A acts as a key regulator of mRNA stability by promoting mRNA destabilization and degradation (By similarity).  In embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (By similarity).  M6A regulates spermatogonial differentiation and meiosis and is essential for male fertility and spermatogenesis (By similarity).  M6A also regulates cortical neurogenesis: m6A methylation of transcripts related to transcription factors, neural stem cells, the cell cycle and neuronal differentiation during brain development promotes their destabilization and decay, promoting differentiation of radial glial cells (By similarity).
What are the official names of this protein?
N6-adenosine-methyltransferase non-catalytic subunit, Methyltransferase-like protein 14.
What is the protein family that this protein belongs to?
Belongs to the MT-A70-like family.
Protein: MIAA_PHEZH
Sequence: MEPRIWLIAGPTASGKSALALRLAEASGAEIVNADSMQLYAGLRVLTAGPGPEETARAPHHLFGSVDPADGWSVGRWLRAASEVIADIRGRGRPVVVVGGTGLYFRALTQGLAEIPEVPADVRAKAAADFERMGEAAFRTRLAEVDPAAAARIAPGDRQRLCRAWEVFAATGQALSDLQRTGAPAIADWSAVALEPPRPALYARCDARLHAMVREGALEEVRALIARNLDPALPAMKAVGVREFAAHLRGETSLEAAVEAAQQETRRYAKRQITWMRGQMAGWPRLTADDHEGQWRQFLAQEPGLTP
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: LIFO_BURVG
Sequence: MSAQQTRAPLLRRIAPYGAAGLAAIVGVAIWSGTGSQSGADASRTPANAVAADGASAAVRQAALPASAALPAPLVGSSAPRLPLDSGGHLAKVRAVRDFFDYCLTARSELTAAALDALVAREIAAQLDATPAQPEALDVWRRYRAYLDALEKLPDGGAVDKIDPEALQRALDQRASIAHRTLGDWSQPFFGAEQSQQRYDLARLRIVQDRTLTDAQKAERLAALDQQMPADERAARAPAERQRAALDQIAQLQKSGATPDAVRAQLTQSLGADVAARVVQMQQDDASWQSRYADYAAQRAQIDAAGLSQQDRDAQIAALRQRIFTKPGEAVRAAAFDRSAAGTR
What is the function of this protein?
May be involved in the folding of the extracellular lipase during its passage through the periplasm.
What are the official names of this protein?
Lipase chaperone, Lipase activator protein, Lipase foldase, Lipase helper protein, Lipase modulator.
What is the protein family that this protein belongs to?
Belongs to the lipase chaperone family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.