PharMolix/UniProtQA huggingface dataset:
Protein: RS12_METJA
Sequence: MSGSKSPRGEFAGRKLRLKRKWCRWHDYNYVRRVLKLKEKYDPLEGAPMARGIVIEKVGLEAKQPNSAIRKCVRVQLIKNGRVVTAFCPGNHAINFIDEHDEVIIEGIGGPKGPRAKGDIPGVKYKVIMVGRNSLRELVRGRQEKIKR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ISPH_AGRFC
Sequence: MNIAVSKPPLTIRLCGPRGFCAGVDRAIQIVVLALKAYGAPVYVRHEIVHNRYVVEGLEAKGAIFVEELHEIPAEHREQPVVFSAHGVPKSVPEDAQARNLFYLDATCPLVSKVHKQAMRHQRLGRHVVLIGHAGHPEVIGTMGQLPEGTVSLVETVEDAGVYEPVDRENLGFVTQTTLSVDDTAGVIARLQERFPAIQAPAADSICYATTNRQDAVKQAAPGCDLFIVVGAPNSSNSKRLVEVALRAGAKHSVLVQRASEIDWNEIGDIRTVGLSAGASAPEVIVDEIIEAFKARFDTTLDLAVTVEETEHFLVNRELRSIELTTDDMAFVNGNASNALPPKATAGI
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: CCA_ECOK1
Sequence: MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLCFRIADETLALMREMTHAGELEHLTPERVWKETENALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAVAGWKEQRCPKPE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RHG44_RAT
Sequence: MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDELAQELIHFELRVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPSFGKPLEEHLMISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNIQEQDKRLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQSEGNITEMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGSYGSPVHVNHNANYSSMPSPDMDPADRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTSWVARRGSSAGRKAACAPPSMQPPAPPSELAAPLPSPLPEQVPDSPATPAPALSPSGASLQPTPERPSVSKSKELSPGSGQKGSPGSIQGTTCPGTQLGPQPAASPSQLPADQSPHTLRKVSKKLAPIPPKVPFVQPGTVSDQPTGQPSPVSLSPTPPSTPSPYGLSYPPGYSMASGQLSPASAPPLASPSVFTSTLAKSRPTPKPRQRPTLPPPQPPSVSLSASSPQSTEHPMLDGMSPGESMSTDLVHFDVPSIHIELGSTLRLSPLEHARRHSVTDKRDSEEESESTAL
What is the function of this protein?
GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases.  Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states.  Acts as a GAP at least for CDC42 and RAC1 (PubMed:25498153).  In neurons, is involved in dendritic spine formation and synaptic plasticity in a specific RAC1-GAP activity (PubMed:25498153).  Limits the initiation of exploratory dendritic filopodia.  Recruited to actin-patches that seed filopodia, binds specifically to plasma membrane sections that are deformed inward by acto-myosin mediated contractile forces.  Acts through GAP activity on RAC1 to reduce actin polymerization necessary for filopodia formation (PubMed:25498153).  In association with SHANK3, promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation (By similarity).
What are the official names of this protein?
Rho GTPase-activating protein 44, Rho-type GTPase-activating protein RICH2, RhoGAP interacting with CIP4 homologs protein 2, RICH-2.
What are the subcellular locations of this protein?
Cell projection, dendritic spine. Recycling endosome. Presynapse. Cell projection, dendrite. Note=In CA1 hippocampal synapses, detected at both presynaptic and postsynaptic sites (By similarity). Located in convoluted dendritic plasma membrane sections enriched in polymerized actin and myosin (patches) along dendrites where often emerge filopodia (PubMed:25498153).
Protein: COXX_BACCR
Sequence: MNHATSELHDESAVTSVPETTRLQDLKALVKMGIVNSNTLTVFTGFWLALHFNGLSVMDNLDKLFFTIVGSGLVMAGVCCLNNYIDRDIDPLMERTKTRPTVTGKYKPGFALTFGLVILLLGFVFLLLTTPMAVLMGFIGAFTYVVLYSLWTKRKYTLNTVVGSISGAVPPLIGWAAIDPSLGHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFEITKRQIMIWTVCLLPLPFYMSGLGITFMVIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFVSMIVVTFF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: F16P_KLULA
Sequence: MAGIKHRRDSAESINTDIITLSRFILDQQHLSAKNATGEFSMLLNSLQFAFKFISQTIRRAELVNLIGLAGASNSTGDQQKKLDVLGDEIFINAMKASGNVKVLVSEEQEDLIVFRNSPGKYAVCCDPIDGSSNLDAGVSVGTIVSLFKIHENQNGNSGEEDSEGTINDVARCGREMVAACYTMYGASTHLVLTTGAGVNGFTLDNNLGEFILTYPELRLPEQKSIYSINEGNTCYWEPTIADFIAKLKENSEENNGKPYSARYIGSMVADVHRTLLYGGLFSYPGDKKNPNGKLRLLYEAFPMAFLVEQAGGKAVNDRGERILDLVPQHIHDKSSIWLGSSGDVDKYLKHIGKL
What are the official names of this protein?
Fructose-1,6-bisphosphatase, FBPase, D-fructose-1,6-bisphosphate 1-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
Protein: COAD_SHIF8
Sequence: MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_KINRD
Sequence: MKLILTHEVSGLGTPGDVVEVKDGYGRNFLLPRNLATPWTKGGEKQVETISKARKARAIASLDEAKAVKQSLEARTVAFAARAGRGGRLFGAVTPADVALAVSAAGGPTVDKRKVEILQPIKTTGTHKALVRLHPDVSATVTIDVVEATA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: FBIC_STRAW
Sequence: MTTSATSGTGPTANSMRRALKRARDGVALDVTEAAVLLQARGEDLDDLTASAARVRDAGLEAAGRAGVITYSKSVFIPLTRLCRDKCHYCTFVTVPGKLRRAGHGMFMSPDEVLDIARKGAALGCKEALITLGDKPEDRWPEAREWLDAHGYDDTIAYVRAISIRILEETGLLPHLNPGVMSWTDFQRLKPVAPSMGMMLETTATRLWSEPGGPHHGSPDKEPAVRLRVLEDAGRSSVPFTSGILIGIGETYEERAESLFALRKISRAYHGIQELIIQNFRAKPDTAMRGMPDAELDELIATVAVARHIMGPRACLQAPPNLVDSEYGRLIGAGIDDWGGVSPLTIDHVNPERPWPQIDLLREQSAQAGFELRERLCVYPEFVQRGEPWLDPRLLPHVRALADPASGLAHADATVEGHPWQEPEEAFVAQGRTDLHHSIDTEGRTGDRRDDFDVVYGDWEALREAAAPGMVPERIDTDVRQALATAANDPTRLTDAEALALLHADGPALDALTRIADDVRKAAVGDDVTYIVTRNINFTNVCYTGCRFCAFAQRRTDADAYTLSLEQVADRAQQAWDVGAVEVCMQGGIHPDLPGTAYFDIAKAVKERVPGMHVHAFSPMEVVNGATRTGLSIREWLTAAKEAGLDSIPGTAAEILDDEVRWVLTKGKLPTATWIEVITTAHELGIRSSSTMMYGHVDQPRHWLGHFRTLARIQQQTGGFTEFVTLPFIHTNAPVYLAGIARPGPTTRDNRAVMAMARLLLHPHIPNIQTSWVKLGTEGAAEMLRSGANDLGGTLMEETISRMAGSSYGSYKSVKDLIAVAEAAGRPAKPRTTLYGEVPQERQRAAAASDGHLPELLPVLD
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
FO synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
Protein: MGM1_YEAST
Sequence: MNASPVRLLILRRQLATHPAILYSSPYIKSPLVHLHSRMSNVHRSAHANALSFVITRRSISHFPKIISKIIRLPIYVGGGMAAAGSYIAYKMEEASSFTKDKLDRIKDLGESMKEKFNKMFSGDKSQDGGHGNDGTVPTATLIAATSLDDDESKRQGDPKDDDDEDDDDEDDENDSVDTTQDEMLNLTKQMIEIRTILNKVDSSSAHLTLPSIVVIGSQSSGKSSVLESIVGREFLPKGSNMVTRRPIELTLVNTPNSNNVTADFPSMRLYNIKDFKEVKRMLMELNMAVPTSEAVSEEPIQLTIKSSRVPDLSLVDLPGYIQVEAADQPIELKTKIRDLCEKYLTAPNIILAISAADVDLANSSALKASKAADPKGLRTIGVITKLDLVDPEKARSILNNKKYPLSMGYVGVITKTPSSINRKHLGLFGEAPSSSLSGIFSKGQHGQSSGEENTNGLKQIVSHQFEKAYFKENKKYFTNCQVSTKKLREKLIKILEISMSNALEPTSTLIQQELDDTSYLFKVEFNDRHLTPKSYLLNNIDVLKLGIKEFQEKFHRNELKSILRAELDQKVLDVLATRYWKDDNLQDLSSSKLESDTDMLYWHKKLELASSGLTKMGIGRLSTMLTTNAILKELDNILESTQLKNHELIKDLVSNTAINVLNSKYYSTADQVENCIKPFKYEIDLEERDWSLARQHSINLIKEELRQCNSRYQAIKNAVGSKKLANVMGYLENESNLQKETLGMSKLLLERGSEAIFLDKRCKVLSFRLKMLKNKCHSTIEKDRCPEVFLSAVSDKLTSTAVLFLNVELLSDFFYNFPIELDRRLTLLGDEQVEMFAKEDPKISRHIELQKRKELLELALEKIDSILVFKKSYKGVSKNL
What is the function of this protein?
Dynamin-related GTPase required for mitochondrial fusion.  Coordinates interaction between the inner and outer mitochondrial membrane to promote the formation of the double membrane.
What are the official names of this protein?
Dynamin-like GTPase MGM1, mitochondrial, Mitochondrial division and morphology protein 17, Mitochondrial genome maintenance protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
[Dynamin-like GTPase MGM1 large isoform]: Mitochondrion inner membrane; Single-pass type II membrane protein; Intermembrane side. Mitochondrion intermembrane space. SUBCELLULAR LOCATION: [Dynamin-like GTPase MGM1 small isoform]: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: LPXA_CHLPN
Sequence: MASIHPTAIIEPGAKIGKDVVIEPYVVIKATVTLCDNVVVKSYAYIDGNTTIGKGTTIWPSAMIGNKPQDLKYQGEKTYVTIGENCEIREFAIITSSTFEGTTVSIGNNCLIMPWAHVAHNCTIGNNVVLSNHAQLAGHVQVGDYAILGGMVGVHQFVRIGAHAMVGALSGIRRDVPPYTIGSGNPYQLAGINKVGLQRRQVPFATRLALIKAFKKIYRADGCFFESLEETLEEYGDIPEVKNFIEFCQSPSKRGIERSIDKQALEEESADKEGVLIES
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNTB_SALA4
Sequence: MEAIKGSDVNVPDAVFAWLLDGRGGVKPLEDNDVIDSQHPCWLHLNYTHPDSARWLASTPLLPNNVRDALAGESSRPRVSRMGEGTLITLRCINGSTDERPDQLVAMRLYMDERFIVSTRQRKVLALDDVVSDLQEGTGPVDCGGWLVDVCDALTDHASEFIEELHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDHRRRMQDIADRLGRGLDEIDACIARTGIMADEIAQVMQESLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWRFGFSLFCILLVVLIGGVTLWLHRSKWL
What is the function of this protein?
Zinc transporter.  Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.
What are the official names of this protein?
Zinc transport protein ZntB.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G3P2_STAAR
Sequence: MSTNIAINGMGRIGRMVLRIALQNKNLNVVAINASYPPETIAHLINYDTTHGKYNLKVEPIENGLQVGDHKIKLVADRNPENLPWKELDIDIAIDATGKFNHGDKAIAHIKAGAKKVLLTGPSKGGHVQMVVKGVNDDQLDIEAFDIFSNASCTTNCIGPVAKVLNNQFGIVNGLMTTVHAITNDQKNIDNPHKDLRRARSCNESIIPTSTGAAKALKEVLPELEGKLHGMALRVPTKNVSLVDLVVDLEKEVTAEEVNQAFENAGLEGIIEVEHQPLVSVDFNTNPHSAIIDAKSTMVMSGNKVKVIAWYDNEWGYSNRVVDVAEQIGALLTSKETVSAS
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 2, GAPDH 2, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI_METKA
Sequence: MYYSSLAEAFERLERISSRKAKISLIAQFLRQCPEDVVDTVALFLANQVFPGWDPRDLGIGSKLMRKVIATATGSTDSEVTELFKRLGDLGLTAEELLKRRKTSTLLDSRPLMVGEVRETFEKIAEVEGEGAVKRKMRLMMGLLARAKPKEARYLVRQALSELRTGVRESTVEEAIAQAFGVSRKLVERAHMLSNDLGLVAKVAMTKGEEGLREIDLRPMRPIKPMLAQAARNVKEALAEVGGKGAVEIKLDGARVQVHSDGEEVRVYTRRIEDVTHALPDIVEAVKDCVDADEFILEGEAVAINPETGKPRPFQELLHRIKRKYDIEEVRKEIPVELHLFDCLYVDGESLVDTPFRERRRRLEEIVREREGEVMLVEQVITDDPKEAAEMFHRALEMGHEGVMVKDLDANYTPGVRGKKMLKVKPVLETLDCVVIGGIWGKGKRKGLIGSYLLAVWDENKENLLEVGKVGTGMDDETLERLTKMFEDLIVEESGREVRFKPEVVFEVEFEDIQKSPKYSSGFALRFPRLVRVRDDLGPEDADTIEKVRRIYEEVLQKH
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: RS15_ACIAD
Sequence: MALTNADRAAIIAKFARAENDTGSPEVQVALLTAQINDLQGHFKEHKHDHHSRRGLIRMVNQRRKLLDYLNGKDHGRYVSLIGELGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PAFA_BIFAA
Sequence: MPQLRDSGNHSTAPLDAHTKDEIQSFARIFGIETEYGVSVTGSDRPCDAGQTAMMMFQPIVAEARSTNTYIENGSRLYLDVGSHPEYATAEARDPMDALALDAAGELVMRDLALDAQRRLRSIQGAGSTVHVFKNNVDSAGHSFGCHENYLVRRFVPLKTIEQELLPFLITRQLFTGAGRMGEQGFQITQRADFLDEAVSSATTRSRPMVNTRDEPHADPDAFRRLHVIIGDSNRSQWATMMKLATTHLVLCVIEQAGREGKDSGFARFSFADASAANHKVSRDLTGVEASFDMADGTVMEGGAVAIQERYLEIVERFVGQHPEVCSSLPRTDVHEVIRRWRRVIEAFRSGVSETFADKVDWLAKRRLFDMLRNRAGGRLSVSKLEQLDMDYHDVANGALYASLCRRGAMRTLVNESQAHEAIDVPPHDTRAALRGRFIQSARSHNAQYSCDWTRLSLTSPNRMDVTLLDPFDAQPSDRFLTILEALQ
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: CRCB1_STAES
Sequence: MQYLYIFVGGALGALIRFCLSMLNEGSTIPLGTFVANLLGAFLMGSIGALSLSLFKTHPNIKKGLTTGLLGALTTFSTFQFELVTLFNQHHFILFTIYGVTSYILGILSCYLGVKIGGRFS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYB_BLABR
Sequence: MTNIRKTHPLMKIINSSFIDLPAPSNISSWWNFGSLLGICLVIQILTGLFLAMHYTSDTVTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVQWIWGGFSVDKATLTRFFAFHFILPFVIAALAGVHLLFLHETGSNNPSGLSSDADKIPFHPYYTIKDILGALILILVLTCLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAFIPLLHTSKQRSMMFRPFSQCLFWVLVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLLLVIMPITSLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y3010_CLOBH
Sequence: MPNKFLIIDNSILPDIFEKVVKVKELLANGKVKDITEGVKTVGISRSTYYKYKDFVFSVSEGVKSQKATIGLLLGHERGTLSKILDRIAEYQGNILTINQDIPINNTANVSITFDISQMSIGLKELVEEIKNTKNVIKVDLIAME
What are the official names of this protein?
UPF0735 ACT domain-containing protein CBO3010/CLC_2906.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: TGT_HELAH
Sequence: MDFQLQAVDKHARAGILNLVHSQVETPIFMPVGTQGCIKSLDAIDMQERLSAKLILANTYHMYLRPGEKVIEQLGGLHHFAQFHGSFLTDSGGFQAFSLSDNVKLQEDGIVFKSHLDGSKHFFTPTKVLDIQYSLNSDIMMVLDDLVGLPAPLKRLEESIKRSAKWANISLEYHKENNRPNNNLFAIIQGGTHLKMRSLSVGLTHGGFDGYAIGGLAVGESTNEMLETIAHTAPLLPKDKPRYLMGVGTPENILDAISLGVDMFDCVMPTRNARNATLFTHSGKISIKNAPYKLDNTPIEENCTCYTCKRYSKAYLHHLFRAKELTYARLASLHNLHFYLELVKNARNAILEKRFLSFKKEFLERYTMDRQ
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: NHAA_PELUB
Sequence: MIKNLSKPFKWFFQLEAASGLVLLIAAIIALVISNSSLSNLYFDTLNQYLFIGINDFGLKLSVHHWINDLLMAIFFFFVTLEIKREFIQGELSNLKKALLPIIGAVGGMVVPALVYVFINLGNSETLNGWAIPSATDIAFSLGILSLLGSRVPISLKVFLTALAIIDDLGAILIIAFFYSGDLSISYLSLILISYILLLTLNKFGVKKFIPYLIIGAFMWFFTYKSGIHATIAGVLLASTIPHRIKEKDFSLLIKLEHAISPYVAFIIMPIFAFANAGVSLEGLSLTSLLEPVPLGILLGLFVGKQVGVMVVSFIAVKFGVAQMPDKSSWLSLYGVSILTGVGFTMSLFVGNLAFAENIQYIDGVKIGVLAGSLLSTVFGYFILLYASKK
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PIR5_YEAS6
Sequence: MHYKKAFLASLLSSIALTAYAPPEPWATLTPSSKMDGGTTEYRTSFGLAVIPFTVTESKVKRNVISQINDGQVQVTTQKLPHPVSQIGDGQIQVTTQKVPPVVSHIVSQIGDGQLQITTAKNVVTKSTIAVPSKTATATATSTATAVSQIHDGQVQVTISSASSSSVLSKSKLEPTKKPNNENVIKVQACKSSGTLAITLQGGVLIDSNGRIGSIVANRQFQFDGPPPQAGAIYAGGWSITKHGTLAIGDNDVFYQCLSGTFYNLYDQSIGGQCNPVHLQTVGLVDC
What is the function of this protein?
Component of the outer cell wall layer.  May be involved in meiosis and sporulation (By similarity).
What are the official names of this protein?
Cell wall protein PIR5, Protein with internal repeats 5.
What is the protein family that this protein belongs to?
Belongs to the PIR protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Covalently attached to the cell wall.
Protein: RT95_VIBCE
Sequence: MNILTTLREQLLTNNVIMPQEFERLEVRGSHAYKVYSIPKRKAGRRTIAHPSSKLKICQRHLNAILNPLLKVHDSSYAYVKGRSIKDNALVHSHSAYVLKMDFQNFFNSITPTILRQCLIQNDILLSVNELEKLEQLIFWNPSKKRNGKLILSVGSPISPLISNAIMYPFDKIINDICTKHGINYTRYADDITFSTNIKNTLNKLPEIVEQLIIQTYAGRIIINKRKTVFSSKKHNRHVTGITLTNDSKISIGRSRKRYISSLVFKYINKNLDIDEINHMKGMLAFAYNIEPIYIHRLSHKYKVNIVEKILRGSN
What is the function of this protein?
Reverse transcriptase (RT) component of antiviral defense system retron Vc95, composed of a non-coding RNA (ncRNA), this reverse transcriptase (RT), a probable ATPase and a putative HNH endonuclease.  Expression of retron Vc95 confers protection against bacteriophages T2, T4 and T6.  At multiplicity of infection (MOI) of 0. 02 cultures slow growth when infected with T4 but do not collapse, at MOI 2 cultures enter growth stasis (PubMed:33157039).  Responsible for synthesis of msDNA (a branched molecule with RNA linked by a 2',5'-phosphodiester bond to ssDNA).  The retron transcript serves as primer (from a conserved internal G residue) and template for the reaction, and codes for the RT (By similarity).  The DNA segment is predicted to be 95 bases long (Probable).
What are the official names of this protein?
Retron Vc95 reverse transcriptase, RT-Vc95.
What is the protein family that this protein belongs to?
Belongs to the bacterial reverse transcriptase family.
Protein: KAE1_METS5
Sequence: MIVLGIESTAHTFGVGVAQDQVPFILANERHTFVPQTGGMKPSEAARHHTLVAHEILRGALDRARISIRDVDGIAVALGPGMGPTLRVGAVVARALSLRFNKKLVPVNHGIGHIEIGYLTTEAKDPLILYLSGGNTIITTYYRRRFRIFGETLDIALGNMMDTFVREVGLAPPYIVDGKHKIDICAEQGSSIIDLPYTVKGEDMSFSGLLTAALRAVKKHNLHDVCLSLREIAYGMLLEATERALALTEKGEIMIVGGVAASGSLRSKLEKLSNDWGVGLKVVPTSFAGDNGAMIAYAGLLALKHGVHIDVKDSTIRPRWRIDEVDIPWRD
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.