PharMolix/UniProtQA huggingface dataset:
Protein: TEKT2_MOUSE
Sequence: MATLSFKPSERYRLSDWRTNSYLLSTNAERQRDASHQIRQEARILRNETNNQIVWDEHDNRTRLAERIDTVNRWKETLDKCLTDLDAEIDSLAQAKESAEQNLQAKNLPLDVAIECLTLRESRRDIDVVRDPVEEELLKEVEVIEATKKVLQEKISQAFQHLCLLQEIRQQLNSDHRDKMETLEIDRGCLSLNLTSPNISLKVNPTRIPKDSTTLQQWDEFTRFNKNRAEAEMKASIELREAIALAIAQTNNELDAQRVATEFTFRKRLREMESFYSELKWQEKNTLEEIAELQGDIRRLEEDLRRKMMNLKLAHTRLESRTYRSNVELCRDQTQYGLIDEVHQLEATINTMKQKLAQTQNALDALFKHLARIQADIACKTNTLLLDTKCMDTRRKLTVPAEKFVPQVDTFTRTTNRTLSPLKICQLELT
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme (PubMed:15340058).  Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia (PubMed:15340058).  Forms filamentous polymers in the walls of ciliary and flagellar microtubules (PubMed:15340058).
What are the official names of this protein?
Tektin-2, Tektin-t, Testicular tektin.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Colocalized with CCDC172 at the perinuclear region (PubMed:24394471).
Protein: COAX_ALKEH
Sequence: MPHWLILDAGNSRLKFGLWDGHRVHATGAVSWSGDWPGELDMALAAMARPERVVVGSVHQTATVEALEAISRRRWGCPLTRITTTAAACGVQNGYRDYRQLGVDRWAAVVAAHLRAPEAWHLVIDVGTAATVDVVGPRGDYRGGAIFPGLRLLADALGSGTAGLPSLAGEAVPLPARSTPDAIRGGVVHGLAGALRHLASEMLPAEAVRPRRWLTGGDAGRLQPLLPQGAVWAPDLVLEGLAQLARESG
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CROOR
Sequence: MTNIRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGICLIAQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYLYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFVVAALAGVHLLFLHETGSNNPSGLNSDTDKVPFHPYYTIKDILGVLIMITVLSSLVLFSPDMLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMLIPFLHTAKQRSMMFRPMSQCMFWILVADLFTLTWIGGQPVEHPFVVIGQLASVIYFLMILLIMPITSMIENQLSKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IRF5_BOVIN
Sequence: MNQPAPAALLPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFYIPWRHATRHGPSHDGDNTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKVYEVCSNGPAPAESQPSEDNAEEEEEEELQKMLPGLSITEAVQPGPAMAPYSLPKEDVKWPPTLQPPVVLAPPAPGPNLLVPAPGNAADFGEVFSEVLPSSQPQPGSLSTSLAPTGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPQSCRLLYSQLEATQEQVELFGPVSLEQVRFPSPEDIPSEKQRFYTNQLLDVLDRGLILQIQGQDLYAIRLCQCKVFWSGPCASAQGSHPNPIQREVKTKLFSLEDFLNELILFQKGQTNTPPPFEIFFCFGEEWPDCKPREKKLITVQVVPVAARMLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWLSQQHLQPVAQTPAMPGLSAAQGPWPMHPVGMQ
What is the function of this protein?
Transcription factor that plays a critical role in innate immunity by activating expression of type I interferon (IFN) IFNA and INFB and inflammatory cytokines downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9.  Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters.  Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction downstream of the TLR-activated, MyD88-dependent pathway.
What are the official names of this protein?
Interferon regulatory factor 5, IRF-5.
What is the protein family that this protein belongs to?
Belongs to the IRF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm: upon activation by the TLR adapter MYD88 and subsequent phosphorylation, translocates to the nucleus.
Protein: UPP_CLOBK
Sequence: MSKVTQIAHPLILHKLALIRDKNTGSKDFRELVEEVAMLMAYEVTRDLQLKEVEIETPICKTKCKMLSGKKVAIVPILRAGLGMVGGMTSLIPAAKVGHIGLYRDEETLKPVEYFCKLPQDIGDRDVIVTDPMLATGGSAKDAITLLKQKGAKHIRLMCLVAAPEGIKEVMDEHPDVDIYVASVDEKLNEKGYVVPGLGDAGDRLYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SSRP_THEMA
Sequence: MVKVVATNKKAYTDYEILETYEAGIVLTGTEVKSLRNGSVNFKDSFCRFKNGELYLLNLHIPPYSHGGVYNHDPERPRKLLLHKRELKRLMGKVQEEGVTIVPLKIYFNDRGIAKVEIAVARGKKKYDKREAIKKREMERKIREYMKYSR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL20_NOCFA
Sequence: MARVKRAVNAQKKRRSILEASKGYRGQRSRLYRKAKEQQLHSLTYAYRDRRARKGDFRKLWIARINAAARLNDITYNRFIQGLKAAGVEVDRKNLAELAVSDAEAFAGLVAIAKAALPQDVNAPAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RPOA_DRIGR
Sequence: MVREEVAVSTRTLQWKCVESRTDSKRLSYGRFILSPLMKGQADMIGIAMRRALLGEIEGTCITRAKSDKIPHEYSTIVGIEESVHQILMNLKEIVLRSNLYGTCDASIFVRGPRCVTAQDIISPPSVKMVDTTQHIASLTEPIDLCIGLQIERDRGYRMKTPNNDQDGSYPIPIEAVSMPVRNANHSIHSYGNGNEKQEILFLEIWTNGSLTPKEALHEASHNLIDLFIPFLHGEEEDINLEDSLNRGTLPFFTFQDKLANLRKNKKAIALECIFIDQSELPPRTYNCLKRSNIHTLLDLLSNSQEDLMRIEHLRIEDVKRILDILQKHFTIDLPKNKF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FORE_DICDI
Sequence: MDNHSSSSNPSSLSSSSSSSSSSSSFLSDHVKKEEQNGLDTIKEEIENKIENEEEEEKIEEKPIEKVEEEKIIVQKEEEEKIEEEPIEKEEEKKVEEEKFEQDNINTTVEAKTLETSTEPIATEVVDEKSITSNNENLEEQQKEDVISIPPPQQEQQEQQEQQEKQKEETKPSIREEVKEKIKGKLSEIKEEIKDIKEEIKHVIREEVTEPIIVVENNNSPPPPPPPPSITVQSSSPVSSQISSPVSSPVSSPKPSVTFNEDGRKRKEGGITASISSEDIMALSSSTSTNNKGIPKENKRTASTILRSKSSPNPGANNPNHNKDGNNSSSSSSSNNNSDNNNNSDNNSNNNNINNNNSSSNNLNYDSSDIDTEAIPKFYHDFKIHRGTSSCVYCGENTRLWSTSYKCFFCGVVCHKKCLDSMNTIPCSSAIHNIKGKNRSQTISGYAPPNSLALQAPPYISVAKPSSITNSSSKSTPSLLSAPPSQSNSNNSSPNISSKSNPNSPITTSATTTTTTATISSLSPTSISSPPIASEQPPSPLLQQQQQQQQQQQQQQQQQQQQQQQQQQISTTQLQDLNNTSEKPDDDMINLMFDTLMVDLDLNLPASKLSTTQKWLLLEQKFKLKKDELLPEYFINALKEQPSKSIFQSLVVILRTNVTKNWMCSFVQLNGVEILFEILSKSKRKDYKDDCLSCIGKVMSNPIGLNSVAQLPMAPKTITKVLRSKQYCIKSKAMAIELLTVMLLDKYVPGGCSLVLKALTKTKEKKRFSFFVRFIKDNESLELKTKALCFINVLIFEMEDMNVRVNIRSEFLRLGLYTYLREIKKTITHEKTLFTQIEIFEEMMNEDTQELDLRLEDLKRQLGIDIDDVDQVFKALKNTTSKSGLNRQLLNILQNLLVIKACDPTDGVKYFILCDTLVKQISLHKGGFEDPSNFDFRGLMVGLESATAEVTLNRKLGELEKQNIDKAMKIQEQDINIKSLLDLLKQLKDGGTAPDASMIKKIEEMIKQMEPPPPPISVKSPDDPNNAAPIVVAPIPPPPPPISGAPPPPPPPPPPMKGGAGPPPPPPPPGKLGAKKPPAGVQCRPPPKVPKPSHPLKAYQWVKLAPVKVNDSLFDKLGPMNDINLPWNQIEEEFAAKVIVREKKAIVKPKGPTQVIDPKLGQNISIFLSQFKGVEPKQLITYIQSMDESKMSRDQVKQISKLLPSREDLAALKEFLQAEDRSKLSIADQYCIDIGAFPFASEKISMFLLKSELKSRLDEVKPQIAAVSVACDEVYKSKKLIRIIEIILVLGNFINYGTPRGDISGYKLDSLIKLSDTKSSDLSSNLINTFVKYCQEKEPNLLTFADELPSLTTARKTIWSGVVADVSSIGRDVHSVKQIVETLQKSNEPFNQSIIDFLATASTEVEKLRKLLESTQENFKKLCKYFAEEEGKSQPEEFFDIFGRFITLFENATTQLQQQKEEQLKEEKRLQQKQQRQERAVRKLTTSNESASASPNHAKSTDDKSDEDDDIVNDLLMAVRDGDAFRQAKGRRRTTHQIATSKMISNNLDPSKILPTSPNKN
What is the function of this protein?
Formins play an important role in the nucleation of actin and the formation of linear actin filaments.
What are the official names of this protein?
Formin-E, Diaphanous-related formin dia3.
What is the protein family that this protein belongs to?
Belongs to the formin homology family. Diaphanous subfamily.
Protein: OPGH_PSEU2
Sequence: MSNSLPVPMSLNEYLAHLPMSDEQRAELAGCTTFAELHERLSAQPVTDPAEAAQASVGRRLTLTTADQLEDAEMLGVDASGRLCLKATPPIRRTKVVPEPWRTNILVRGWRRLTGKGNPPKPEHDDLPRDLPKARWRTVGSIRRYILLILMLGQTIVAGWYMKGILPYQGWSLVSLDEITRQTFVQTALQVMPYALQTSILLLFGILFCWVSAGFWTALMGFLELLTGRDKYRISGASAGNEPIEKGARTALVMPICNEDVPRVFAGLRATFESVAATGDLDRFDFFVLSDTNETDIAVAEQQAWLDVCRETKGFGKIFYRRRRRRVKRKSGNLDDFCRRWGGDYRYMVVLDADSVMSGECLTSLVRLMEATPDAGIIQTAPRASGMDTLYARMQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRMKPFIEHCALAPLPGKGAFAGAILSHDFVEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFFFLVLSTALLAVNTLMEPTYFLEPRQLYPLWPQWHPEKAVALFSTTIVLLFLPKLLSVILIWAKGAKGFGGKFKVTVSMLLEMLFSVLLAPVRMLFHTRFVLAAFLGWAATWNSPQRDDDSTPWIEAVKRHGPQTLLGACWALLVFWLNPSFLWWLAPIVVSLMLSIPVSVISSRTNLGVKARDEKFFLIPEEFEPPQELISTDRYTYENRWHALKQGFIRAVVDPRQNALACALATSRHRQAQPIEVVRMERVDQALKVGPAKLGNQERLMLLSDPVALGRLHERVWSEGHEEWLAAWRASIEADPHAPLLPLQPEGKASEPVPV
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU2M_VIVTA
Sequence: MKPPIFIIIMSTVISGTVIVMTSSHWMLTWIGFEMNMLAIIPILMKKFNPRAMEASTKYFLTQATASMLLMMGIIINLLHSGQWTVSNNLNPMASILMTTALAMKLGLAPFHFWVPEVTQGISLSSGMILLTWQKIAPLSILYQISPTINPHLLLPMAILSVLIGGWGGLNQTQLRKIMAYSSIAHMGWMAAILLYNPTMMFLNLIIYITMTLTTFMLFMLNSATTTLSLSQTWNKAPLITSLILTLMLSLGGLPPLSGFTPKWMIIQELTKNEMIILPTFLAITALLNLYFYMRLTYATALTMFPSTNNMKMKWQFESTKKTIFLPPLIIISTMMLPLTPMISILD
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NFIP1_XENTR
Sequence: MSEQSSSRYQQLQNEEEPGENPQASTDAPPPYSSIAGESSGLFDYKDELGFPKPPSYNVATSLPSYDEAERTKAEATIPLVPGRDDDFVARDDFDDADQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTSSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPDNFSTLPRTRVLFIY
What is the function of this protein?
May play a role in Golgi structure maintenance.
What are the official names of this protein?
NEDD4 family-interacting protein 1.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: Y3486_MYCTU
Sequence: MAITGSAAPSWPRLLHAEGPPSVICIRLLVGLVFLSEGIQKFMYPDQLGPGRFERIGIPAATFFADLDGVVEIVCGTLVLLGLLTRVAAVPLLIDMVGAIVLTKLRALQPGGFLGVEGFWGMAHAARTDLSMLLGLIFLLWSGPGRWSLDRRLSKRATACGAR
What are the official names of this protein?
Uncharacterized membrane protein Rv3486.
What is the protein family that this protein belongs to?
Belongs to the DoxX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CVC2_HHV8P
Sequence: MLTSERSYLRYPKNRRWTEAGRFWAPHPENVLFIHKPTMEETRRVALGLRSQLVRNRERKTKAHLLSLELDRLVQVHDSRVRVINADIDAVKQMIGNMTWSDNIDMPQSRSHEPPLVTSPPQASHRNFTVAIVPGDPHFSVDRDLRGELMPTLYMNQNQWLPSFGPWFISLTDNAMQRRVFPKELKGTVNFQNSTSLKLISHTLTTVASTTADFFADARHLTDTQAALCLVNAYFCQKTSRQLPATPDDLLADLPQKLDLLITQLKQESGPGDFSFTYSNPQERASLAPLNKESRYPTAFFQRHKLHAMMAKAGLFPHNKGTGAPGTAPAMDLVFAITSAMFGSDIPPFSAYQWNLRAGIVALEVFILAYGLLEFGQVARGHPNRRLNLVSLLGPKFQPGALPDPNAPMLKRGQLFSFISEHYIIPTLQANPNAPVSFIFPGIILAALEARSTVSHKQPGPFVNLTGSRFNEIFEILNQQLTFRDPLALLQARTALRLATEEGLDVLLSHPSPPTLLQEIIKSQFGGGDDYDRAYFMVLGCLPVVLAVV
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.  Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.
What are the official names of this protein?
Capsid vertex component 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: HIS4_BRAHW
Sequence: MYILPAIDLKNGEVVRLVEGNYDNKTTYFKDPLEVLDFFIESGSSYLHVVDLDGASDGETINFKTIEKVIKKCDLFVEVGGGIRNEDTIKKYLDIGVKRTILGTAAVENIDFTNNMINKYKEHIAVSIDSRDRMIAVKGWKEINKQDSVEFCMKLDSMGIDTIIYTDISKDGKLSGTNLDIYKELREKISCNIIASGGVTFEDEIIKLRDMKINGAIVGKAIYEGKIDLKKIIEIAKQ
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4489_BACAN
Sequence: MISQSTLFLFILLIIGLIAKNQSLTVAIGVLFLLKFTFLGDKVFPYLQTKGINLGVTVITIAVLVPIATGEIGFKQLGEAAKSYYAWIALASGVAVALLAKGGVQLLTTDPHITTALVFGTIIAVALFNGVAVGPLIGAGIAYAVMSIIQMFK
What are the official names of this protein?
UPF0756 membrane protein BA_4840/GBAA_4840/BAS4489.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF1_METCA
Sequence: MSKEDHIEMEGKVIETLPNTTFRVQLDNGHVVIAHISGKMRKNYIRILTGDRVKVELTPYDLSKARITFRHR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3L21_TROCA
Sequence: MKTLLLTLVVVTIVCLDLGNSFSCYKTPHVKSEPCAPGQNLCYTKTWCDAFCFSRGRVIELGCAATCPPAEPKKDISCCSTDNCNPHPAHQSR
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 1, LNTX-1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: G6PI_PHOLL
Sequence: MKNINPSQTSAWKALEQHFAQIKDIHLRELFEQDPDRFAKFSATFDDQILVDFSKNRITTETLKKLQALAKETDVAGAMRSLFSGEKINCTENRAVLHIALRNRSNTPMMVDGEDVMQQVNAVLAKMKDFSERVIHGEWKGYTGKGITDVVNIGIGGSDLGPYMVTEALKPYKNHLNMHFVSNVDGTHIAETLKALNPETTLFLIASKTFTTQETMTNAHSARDWFLKSAGDEGHIAKHFAALSTNGQEVKQFGIDTKNMFEFWDWVGGRYSLWSAIGLSIALSIGFENFEQLLSGAHAMDQHVANTPFEQNIPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYIDRNGHPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAISHNPLSDHHSKLLSNFFAQTEALAFGKSREQVDAEFATSGKTVVEVEHVAPFKVFEGNRPTNSILLREITPFSLGALIAMYEHKIFVQGAILNIFTFDQWGVELGKQLANRILPELKDDNRVVSHDSSTNGLINRFKAWR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABP1_RIPCL
Sequence: MRSPRVIHLACVIAYIVAVEAGDKPVYLPRPTPPRPIHPRLAREVGWELEGQGLSPLSEAELLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSVAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRVASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEEEVLPEVRERGSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSVAEDLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDATLESELSPSSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEGLPEVRERRSPGGQGGYLPRPTPRTPLCRSRRDANLDAEQSPVSEGVVLPEVR
What is the function of this protein?
Has antibacterial activity in vitro.
What are the official names of this protein?
Probable antibacterial peptide polyprotein.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14Z_ROSCS
Sequence: MARKALMVKAQRPQKYTVRAYNRCKICGRSRAYMRKFGMCRICFREHALRGLIPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: AMO_LENCU
Sequence: KFALFSVLTLLSFHAVFSFTPLHTQHPLDPITKEEFLAVQTIVQNKYPISNNKLAFHYIGVDDPEKDLVLKYETSPTLISIPRKIFVVAIINSQTHEILIDLTIKSIVSDNIHNGYGFPVLSAAEQFLAIDLPLKYPPFIASVNKRGLNISEIVCSSFTMGWFGEEKNSRTVRVDCFMKESTVNIYVRPITGITIVADLDLMKIVEYHDRDTEAVPTAENTEYQVSKQSPPFGPKQHSLTSHQPQGPGFQINGTSVSWANWKFHIGFDVRAGIVISLASIYDLEKHKSRRVLYKGYISELFVPYQDPTEEFYFKTFFDSGEFGFGLSTVSLIPNRDCPPHAQFIDTYIHSADGTPIFLENAICVFEQYGNIMWRHTETGIPNESIEESRTEVDLAIRTVVTVGNYDNVLDWEFKTSGWMKPSIALSGILEIKGTNIKHKDEIKEEIHGKLVSANSIGIYHDHFYIYYLDFDIDGTQNSFEKTSLKTVRIVDGGSKRKSYWTTETQTAKTESDAKITIGLAPAELVVVNPNIKTAVGNEVGYRLIPAIPAHPLLTEDDYPQIRGAFTNYNVWVTPYNRTEKWAGGLYVDHSRGDDTLAVWTKKNREIVNKDIVMWHVVGIHHVPAQEDFPIMPLLSTSFELRPTNFFERNPVLKTLPPRDFTWPGCSN
What are the official names of this protein?
Primary amine oxidase, Amine oxidase [copper-containing].
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
Protein: METRN_HUMAN
Sequence: MGFPAAALLCALCCGLLAPAARAGYSEERCSWRGSGLTQEPGSVGQLALACAEGAVEWLYPAGALRLTLGGPDPRARPGIACLRPVRPFAGAQVFAERAGGALELLLAEGPGPAGGRCVRWGPRERRALFLQATPHQDISRRVAAFRFELREDGRPELPPQAHGLGVDGACRPCSDAELLLAACTSDFVIHGIIHGVTHDVELQESVITVVAARVLRQTPPLFQAGRSGDQGLTSIRTPLRCGVHPGPGTFLFMGWSRFGEARLGCAPRFQEFRRAYEAARAAHLHPCEVALH
What is the function of this protein?
Involved in both glial cell differentiation and axonal network formation during neurogenesis.  Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia.  Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity).
What are the official names of this protein?
Meteorin.
What is the protein family that this protein belongs to?
Belongs to the meteorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YVAB_VACCC
Sequence: MLFRILSLNLIKIKKRRRRHLPNLLRRYQQLHVHNNRMEIFLVLLQRLHLLNLLLWPLYVLLHLLVVQYVQQHNKIQIQEQHLNKI
What are the official names of this protein?
Uncharacterized 10.7 kDa protein.
Protein: NA13_BUNCI
Sequence: GVACRCDSDGPTSRGNTLTGTLWLTGGCPSGWHNCRGSGPFIGYCCKK
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation.  This toxin has moderate activity on Nav1. 1/SCN1A (EC(50)=about 300 nM) and Nav1. 5/SCN5A (EC(50)=307. 00 nM).  It less potent on Nav1. 4/SCN4A (EC(50)=820. 84 nM), Nav1. 6/SCN8A (EC(50)=about 900 nM), Nav1. 2/SCN2A (EC(50)=1449. 17 nM) and Nav1. 3/SCN3A (EC(50)=1458. 42 nM) (when measured as the increase in the slow component).
What are the official names of this protein?
Delta-actitoxin-Bcs1a, Delta-AITX-Bcs1a, Bc-III, Major neurotoxin BcIII.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: CLPX_LEPBJ
Sequence: MAKKTPGTNGKQKLFCSFCGKEQDAVKRLVAGPGVYICDECISLCNEIIAEDHEHSHEKSEVFSEIPNPVDIKSILDQYVIGQDHAKKALSVAVYNHYKRVNLKEKKSDVEIEKSNILLIGPTGSGKTLLAQTLARIIKVPFAIVDATALTEAGYVGEDVENIILKLIQNAENDIKKAEIGIIYIDEVDKIARKSDSASITRDVSGEGVQQALLKIIEGTIANVPPQGGRKHPHQEYLQVDTKNILFILGGAFVDLPNIIKSRTGVKTIGFGSEEQRIQAENKDTLMEQVIPEDLIKFGLIPEFIGRLPIVATLQELNVDMLKQIFREPKNSVLKQYTRLLELENVKLTFHEDAIDKIAELAIKRESGARGLRAIVENIMLDLMFDIPSRKDIEEVIITAEVITDRVTPTLILKKESKIA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CRCB1_LACPL
Sequence: MLVLVGLAGAGAAVGALSRYGIMRLALPLNRWPLPIATLFINLTGALLLGWILTSSLPPNWQIFLGTGIMGGYTTFSTMINELVLLGRNHHQRVAWEYFGLSLVGGLVMVYLGTLI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.