PharMolix/UniProtQA huggingface dataset:
Protein: SLUR2_MOUSE
Sequence: MRLPFWFLLAVVLSMELAVTQGLQCHLCKGFGGCSRPSSCPWSSTHCVIIATRSPISFTDLPLVTKMCYSGCPDVSSLGLGPHVSIACCQSNLCNRD
What is the function of this protein?
Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors.  May regulate keratinocytes proliferation, differentiation and apoptosis.  In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs, strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs.  Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner.
What are the official names of this protein?
Secreted Ly-6/uPAR domain-containing protein 2, SLURP-2.
What are the subcellular locations of this protein?
Secreted.
Protein: EIF3C_CRYNJ
Sequence: MSFFAKLQGSDSESSSGSESEESILSGSEGERQDKKLAAQKKQQKSKASMFLNSEESESEEESSDEDEEEMSDSDDERQAVANKFLNDAASSDEESEEEDKIIVLSAKDKRFAEMEAAIHSIQNAVKNTDWVLASSELDKLFRFIARHLVTIVASPIPAEGHIPPRFLETLVSLEADVAKTLAAEKSAPKKMAPAKAKAVNGIRQTLKKKSKEFDGVLKTYNEDPEAYTAAYEKANAAPAAPKPKKAAVTTPGEGEDDEFMTIGKGGKTLNLTADGVFKTLREIFEARGRKNTDRAETIKILTKLLEVSETTYQKIRVLLALVPARLDYSQHLVSIPQESWVTALQEFDQLISILIAEPDYLVQETVGEYDDLVERTPEVVDGKKQKVLIAGSLISLLESLDSELTKTLQHTDAHEKGDEYIDRLKHEAPLYTTIVKAQTLFEREQLSDNIARTVIRRLEHIYAKPDIIIEHFESKATQAAAGLKSEITPFDVKRDASGVIHDLAVFIYQSDAPVLRARAILYHIFNQALHGRYHQARDLLLMSHLQDTISHADVTTQILYNRAVMQVGLAAFRLGFIPECQTILSEMFSTLRQKELLAQSVQRYNIQLSPEQELLEKRRLLPFHMHLNVELLEAAYLTSCMLVEIPLLASVDTEEQRRRVTSKTFKRLLDMADRQAFMGPPENTRDHIIKASQALQAGEWEKARDLIVSIKVWSLLDNAAEVKDILAKKIQEEGLRTSLFTYAAYYDSLSLSHLASTFNLPVGRITSIISRMIYTDELAASLDQIDGVVIFHRVEQSEVQRLAQQLAERTASMLEQNEKTLDVKLGNQGQGQDRDTRAVGGEGGRQQGERRGGRGTYRGRGGRGGRGGFNQGLGTTMGRRVTAQ
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 93 kDa subunit homolog, eIF3 p93, Translation initiation factor eIF3, p93 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_GAZGA
Sequence: MINTRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTADTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGISSDADKIPFHPYYTIKDILGALLLILVLMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILILMPLLHTSKQRSMMFRPISQCLFWILAADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVLMPAASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NHAA3_ACICJ
Sequence: MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFRSLWETPIGIQIGAFQFLRSLRDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVALSVVAAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGCLALLGSRVPPGLRVFLLSLAVVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVNASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIAVRETLSPVERLEAMLHPWVAFGVMPLFALANAGVPITIKGLINPVSLAVMAGFVLGKPIGVTAFAWLGVRTGVAIRPAGLTWGGLVGGALLTGIGFTMALFIAGQAFQDATLNAAKLGILAASVVSSVAGLTLLCALPRSDGTPMFRGRRGGGEHP
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 3, Sodium/proton antiporter NhaA 3.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRM82_ASPFU
Sequence: MVVNYQHPIQCIRYVEKQTAGFRNLFLASAGSKIYTYAAETGRKLAIWPEAPNASHSTVVSVAPSSEGDEPSAKKRKVSPVPEQTAKGGQPEASTAWSTIPILTVSSDGNFLVAVTGEDKCLRVFEIEESGHLKQLSERHMPKRPSAITLVDDDKTILCGDKFGDVYSLPLIDTGKSSIAPKIHAKMKPNQPAATTLTVHSKRNLASLEQQLRHYSQNEKTAEEKPTSAFELHLILGHVSMLTDLVYVSVPVDATSGRQRPYIFTADRDEHIRVSRGPPQAHIIENYCLGHTSFVSSLCVPQWAPEYLVSGGGDNHLIVWRWNESRLVQKVPLLEEGTDSEVVVRRIWALSLTKAANSQENANVILVALDGSSKLLCFTLESDGSLKAQNSIQASGNVLDLTVPSENSSIVVSVDAVREAGSTQEWRTSPSSPSTLVEAFRLKPASEGPLDWERTSEAITAQINSEGTSDISADLDEKQKKELNDSLYSLGNLRKKNMGEDD
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit trm82, Transfer RNA methyltransferase 82.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y8611_DROME
Sequence: MVENISLNVTVKSSARKNQQQSPALSVKKRAQKSQDFDFQFNVDKPKVKAIVVRRRAPPSKVEPTNSSVPNTTKSPTPSVSSSKSAISTLSASPKANASNDDLMFNVSPTKPPVKSVLGDDFMLNVTTKPVVAQKAKPKITRAERLGKKQRQGKPLTKLSEEQITRALKSNKKPKNPNQLPTPGDLFRAQLEEERRQKRREEGGGDQEASADEEDAKNNSGGGSPRVKPSSAVKESKKSSDIEDSGESGEESATSDEEPDESSAQSPGQEKEPKQTAKKPPKAEETSSTNRFRTKKIGLFDQSDVEALKQLGQRAVKPVKETIFTGSKISTLGLHPHAVKNLEDLLSIRELTSVQQKTIPEVLQGKDVLVRSQTGSGKTLAYALPLVELLQKQQPRIQRKDGVLALVIVPTRELVMQTYELIQKLVKPYTWIVPGSLLGGESRKSEKARLRKGINILIGTPGRLVDHLLHTASFKLTKLQFLILDEADRLLELGYERDVKQLVEAIDKQRAECEDKELPQLQRMLLSATLTSQVQQLAGLTLKNPLYIDNSDEAASAALKSKDGYQKETIEALLEVDDGLGEYQEDVTGVLSIPENLQLSYVVVPPKLRLVALSSLLAKEVDASPKQFKAIVFMSTTEMVNFHHDMLNEALTRRVLDEEDEQEKGDSDDDGDIPLLQGLRFFKLHGSMTQTERQGVFRGFRDCASCVLLATDVVGRGIDVPDIKLVVQYTPPQTTADFVHRVGRTARAGRKGRAVLFLTPSEAQFVRHLEKKRIRIQQGDMYAYLQTLLPKDDEARTVQEAASNLQHKFQTLLEDDRELHDKSCKAFVSWMKFYSTFPKELKPIFNVRIAHMGHFAKSFALKEAPSKFAAKHAAPKAAPPTNRLTYTERDPEKIQAQKRAKRRFTTTVSGEVRQLQQRDVGAQKPGAPPPKGGFIGGGVGRSSFMKSLGKSRALNMSEFDSGLPPEGAAKRRKQA
What is the function of this protein?
Probable ATP-dependent RNA helicase.
What are the official names of this protein?
Probable ATP-dependent RNA helicase CG8611.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
Protein: PRGR_PANPA
Sequence: MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSNEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQGVLSPLMSRSGCKAGDSSGTAAAHKVLPRGLSPSRQLLLPASGSPHWSGAPVKPSPQPAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTMMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPSASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRAPPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLSGLPQLGYQATVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGIPNESQALSQRFSFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcriptional activator of several progesteron-dependent promoters in a variety of cell types.  Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity).
Protein: LUR12_ARATH
Sequence: MKLPIIFLTLLIFVSSCTSTLINGSSDEERTYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISDIK
What is the function of this protein?
Pollen tube attractants guiding pollen tubes to the ovular micropyle (PubMed:23271953, PubMed:29109411).  Attracts specifically pollen tubes from A. thaliana, but not those from A. lyrata (PubMed:23271953).  Triggers endocytosis of MDIS1 in the pollen tube tip (PubMed:26863186).
What are the official names of this protein?
Protein LURE 1.2, AtLURE1.2, Cysteine-Rich Peptide 810_1.2, CRP810_1.2, Defensin-like protein 213.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted. Note=found at the micropylar end of the female gametophyte, possibly at the filiform apparatus of the synergid cell. Difuses to the surface of the funiculus of the ovule through the micropyle.
Protein: NUOI_LEPBL
Sequence: MGTVNVVRVASLHKLSWYEKFYFYSIGKGLWITLKHFIKAAILRRTVTIEYPEKKRKYSTRFRGMHTMKRDEQGRERCTSCFCCMWICPADAIYIEAGEVVPEIQHLHPEDKYAKKFEIDLLRCIFCGMCEEACPKGAIYLDGPGEMATDNREDLILTKERMMQIVGGPIIGERQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ALLC_ACIBS
Sequence: MATLHAPAFELPEILNTKTNLADARIGAQVIECSDDFFAEAKRMLQFEAPIFVEDKFDDHGKWMDGWETRRKRHAGYDWCIVKLGVSGKISALDIDTTFFTGNYPASASLEACYAPNSDLTGAKWQSILENTELGPSQHHIFMVNNDAIFTHIRLNIFPDGGVARLRVYGDVHIQVTDHEQTLDLLALENGGRVIAYSDAHFGHPRNLINPGRGVNMGDGWETKRRRAPGYDWCILALGKSGKIEKIEIDTAHFKGNFPAEVSIQAVYLENATDAQLIPQSMFWSYLLEAQPMQMDHIHEYMNEILQHEKVSHIRINMIPDGGISRVRLWGKIAKS
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: RL17_SACEN
Sequence: MPTPTKGARLGGSPSHERLMLANLATSLFEHGKITTTEAKAKRLRPLAERLITKAKKGDLHNRREVMKTIRDKDVVHKLFAEIGPHFADRNGGYTRIVKAMPRRGDNAKMAVIALVTEKTVTAEAEAARGTKFAKDEKAKAEATEAKAEETTETTESTEAESTEAPAEEAKAEDTAAEKKDES
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: EFTS_SHEB8
Sequence: MAITAAQVKELRDRTGAGMMDCKNALTETNGDMELAIDNMRKSGAAKAAKKAGNIAADGTILIKNGEGFAALLEVNCQTDFVAKDSNFLAFANAVLDAAAASKVTLEDLKAQFEDARVALVTKIGENINIRRVEYIDGANLSSYRHGERIGVVVAGEADEETLKHIAMHVAASKPEYVNPEDVPAEIVAREQALQIEMSMNEGKSAEIAEKMVLGRMKKFTGEISLTGQAYIMEPKKTVGEILKEKGAKVTNFIRLEVGEGIEKKEEDFAAEVAAQIAASKKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_PARDP
Sequence: MDMALPEFSMRQLLEAGVHYGHQTQRWNPRMAEFIYGERNGIHIVDLTQTVPMLDAALQVVRDTVAKGGRVLFVGTKRQAQKAVADAAERSAQFYMNHRWLGGTLTNWKTVSQSIQRLKALDETLGSGAEGLTKKERLQMEREQAKLQASLGGIREMGGLPDLLFVIDVNKEDLAIAEAKKLGIPVVAVVDTNCSPKGVDYVIPGNDDAARAIALYCDLVSRAALDGMTAQMGAAGVDLGALEASVEEELTGETAEEAAEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: LPXK_BURTA
Sequence: MSARPGLLARAEARLTREWQRRGALAWALTPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGAKIVAPTAVTPASAPQQAGDEPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLARPSRRKPLAQFAGERVLAAAGIGAPERFFATLRAAGVTPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIWVVPVEAALDPRLIALVVEKLRGRTSA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RS7_BRAOL
Sequence: MFSAQNKIHKDKGVAPTEFEERVAQAFFDLENTNQELKSDLKDLYINQAVSMDIAGNRKAVVIYVPFRLRKAFRKIHSRLVRELEKKFSGNDVIFVATRRIMRPPKKGSAVQRPRNRTLTSVHEAMLEDVAYPAEIVGKRTRYRVDGTKIMKVYLEPKERNNTEYKLETMVGVYRKLTGKDVVFEYPVADP
What are the official names of this protein?
40S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS7 family.
Protein: HNL_MANES
Sequence: MVTAHFVLIHTICHGAWIWHKLKPALERAGHKVTALDMAASGIDPRQIEQINSFDEYSEPLLTFLEKLPQGEKVIIVGESCAGLNIAIAADRYVDKIAAGVFHNSLLPDTVHSPSYTVEKLLESFPDWRDTEYFTFTNITGETITTMKLGFVLLRENLFTKCTDGEYELAKMVMRKGSLFQNVLAQRPKFTEKGYGSIKKVYIWTDQDKIFLPDFQRWQIANYKPDKVYQVQGGDHKLQLTKTEEVAHILQEVADAYA
What is the function of this protein?
Involved in cyanogenesis, the release of HCN from injured tissues.  Decomposes a varieties of (R) or (S) cyanohydrins into HCN and the corresponding aldehydes and ketones.  The natural substrate of this enzyme is (S)-acetone cyanohydrin.
What are the official names of this protein?
(S)-hydroxynitrile lyase, (S)-acetone-cyanohydrin lyase, Oxynitrilase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydroxynitrile lyase family.
Protein: PKNK_MYCTU
Sequence: MTDVDPHATRRDLVPNIPAELLEAGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDNLERFLREQRAMGRLSGHPHIVTVLQVGVLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLAGALEAAHRVGTLHRDVKPGNILLTDYGEPQLTDFGIARIAGGFETATGVIAGSPAFTAPEVLEGASPTPASDVYSLGATLFCALTGHAAYERRSGERVIAQFLRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGEELRDVQRRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLRLPRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEFLSENVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAMLEEAEHRGLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAENGYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSMVVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQADLRAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAICRFEFAEVYPLLDWAAPYQEMMGPFGTVYAQCLRGMAARNRLDIVAALQNFRTAFEVGTAVGAHSHAARLAGSLLAELLYETGDLAGAGRLMDESYLLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPRLAARINNERIRLGIALPAAVAADLLAPRTIPRDNGIATMTAELDEDSAVRLLSAGDSADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA
What is the function of this protein?
Key microbial factor involved in regulation of early and late events in tuberculosis infection, and in host-pathogen interactions.  Modulates host immunity during early infection.  Slows mycobacterial growth during chronic infection in host and during a variety of stress conditions in vitro.  Regulates the expression of a large subset of tRNA genes as a means to facilitate adaptation to changing growth environments.  In vitro, directs the inhibition of transcription and translation processes in a phosphorylation-dependent manner.  Phosphorylates the transcriptional regulator VirS, thereby increasing the affinity of VirS for the mycobacterial monooxygenase (mymA) promoter.  In vitro, can also phosphorylate the mycobacterial monooxygenase operon products Rv3083 (MymA), Rv3084 (LipR), Rv3085 and Rv3088.
What are the official names of this protein?
Serine/threonine-protein kinase PknK, Protein kinase K.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Secreted, cell wall. Note=Probably attached to the cell membrane through interactions mediated by its C-terminal region. May be secreted during infection.
Protein: CX7A2_ONCMY
Sequence: KNKVPXXQKL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7A-heart, mitochondrial, Cytochrome c oxidase subunit VIIa-heart.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIa family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PSD_CLOB8
Sequence: MIQVYNRTTKSYEEELIAGKKYIEWTYESPVGKTITELIAKKKLFSKLYGKYCDTKLSKSKISPFVDSFNIDMAMSKKKINEFKSFNDFFTRELNFDARPINSDNNILISPGDGRITAYEDIDLDNIIQIKGLTYSLKELINDDNVASKYKNGICVVLRLCPTDYHRFHFIDSGIPYENHPIKGHYYSVNPIALKSVPKLFCENKREWSLFKSDNFKDVLHIEVGATCVGSIIQTYSPRVRVNKGDEKGYFKFGGSTTILFFEQGSIEIDADIIEQSKLGFECKVIFGENIGTKVL
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EFTU_SULNB
Sequence: MAKEKFERTKPHINIGTIGHVDHGKTTLTAAITAVLAVAGDTELMDYDAIDNAPEERERGITIATSHVEYETATRHYAHVDCPGHADYVKNMITGAAQMDGAILVIAATDGPMAQTREHILLSKQVGVPYIVVFLNKEDQLDDEDKEEMLELVEMEVRELLSEYDFPGDDTPIVAGSAFQALEEAKTGTLGEWSAKIMELMDAVDEYIPEPKRETDKDFLMAIEDIFTIQGRGTVVTGKVDRGQVCVGDEVEIVGLKDTQKTTVTGVEMFRKEMDCGIAGDNCGVLIRGIDKEAVQRGMVLCKPGSITPHTQFEAEVYVLTKEEGGRHTPFFDNYRPQFYVRTTDVTGSVKLQEGTEMVMPGDNVKINVELIAPIALDEGTRFAIREGGRTVGAGVVSKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_DELAS
Sequence: MASITRQAYAEMFGPTVGDRLRLADTALVIEIEKDHTIYGEEVKFGGGKVIRDGMGQSQRMAADCADTVITNAVIIDHWGIVKADIAIKNGLIAGIGKAGNPDMQPGVTIVIGPGTEIIAGEGMIVTAGGIDTHIHFICPQQIDEALTSGVTTMIGGGTGPATGTFATTVTPGPWHMERMLQAVDGYPMNIGLLGKGNASQAAPLREQIAAGAIGLKLHEDWGSTPAAIDCCLGVADETDTQVAIHTDTLNEGGFVEATVAAFKGRTIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTRPYTVNTLDEHLDMLMVCHHLDASIAEDIAFAESRIRRETIAAEDVLHDLGAFSMISSDSQAMGRVGEVVLRTWQTAHKMKVQRGSLPGDNARHDNFRVKRYVAKYTINPARTHGIAHVVGSVEVGKLADLVLWRPAFFGVKPSLILKGGSIASAAMGDPNASIPTPQPVHYRPMFAGQGSGVAAASLTFVSQAAQQAGVADRYGLRKRTVAVENCRSVSKRDMVHNDWQPDISVDPETYQVVADGQLLTCEPATELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAM_YERP3
Sequence: MIRKAFVMAVNPDAHAEYQRRHTPIWPELESVLKAHGAHHYSIFLDETRNLLFGVVEIESEERWNAVAQTAECQRWWQHMADVMPSHPDNSPVSQALREVFYLE
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.