PharMolix/UniProtQA huggingface dataset:
Protein: MRP1_MACFA
Sequence: MALRGFCSADGSDPLWDWNVTWYTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTLLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIMTALKEDVQVDLFRDMTFYVYFSLVLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKDSSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPEILKLLINFVNDTKAPDWQGYFYTALLFVAACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPPILAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALCTFAVYVTIDKNNVLDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGDTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVALKGSVAYVPQQAWIQNDSLQENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQDPEDNGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDVSRQHNSTAELQKDGAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFICNHVAALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSNWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIARIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYNMARDAGLV
What is the function of this protein?
Mediates export of organic anions and drugs from the cytoplasm.  Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics.  Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed:12657726).  Hydrolyzes ATP with low efficiency.  Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (By similarity).  Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).  Mediates ATP-dependent, GSH-independent cyclic GMP-AMP (cGAMP) export (By similarity).  Thus, by limiting intracellular cGAMP concentrations negatively regulates the cGAS-STING pathway (By similarity).
What are the official names of this protein?
Multidrug resistance-associated protein 1, ATP-binding cassette sub-family C member 1, Glutathione-S-conjugate-translocating ATPase ABCC1, Leukotriene C(4) transporter, LTC4 transporter.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COX16_COCIM
Sequence: MPVFQTKRFRPSTSAGSTLGDRIGQMYRAHLSKHPFLLFGLPFLSLMVAGSFVLTPATALRYERHDRKVQQVSQQEALALGIKGPDGDGENDIKMNPRRRVLGSEKEEYYRLMAKDLDNWEQKRVQRWKGEPDGRLS
What is the function of this protein?
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.  May participate in merging the COX1 and COX2 assembly lines.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RLMN3_OPITP
Sequence: MKFTPAKPPLTGETLESLTARLRERGEPAFRASQILDWVYKKRARSWDGMTNLPKPLRTWLDDTFDLMPATLVLNKQSADVTDKLLLELRDGSLIETVIIRAPQEGVGQDHSRKTICISTQVGCAMGCVFCASGLAGLKRDLSAGEIVAQLLQVCYREDALTPRAHMELASFDNIVVMGMGEPLANYDALIRALTILNADWGLGFGARRITVSTSGLVPKILQLADEPLGFRLAISLHGATDEVREKIMPVNKAFPLAKLLPAVKAFSEKHGRMITLEFILIDGVNDSLEQAEKLRDIALDLHAHVNLIPYNTVEGLAWKRPSITRQERFADVLRARRVSVTLRREKGHDIDAACGQLRLKTEKERQVLAAAKT
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN 3, 23S rRNA (adenine(2503)-C(2))-methyltransferase 3, 23S rRNA m2A2503 methyltransferase 3, Ribosomal RNA large subunit methyltransferase N 3, tRNA (adenine(37)-C(2))-methyltransferase 3, tRNA m2A37 methyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_ACET2
Sequence: MKHARQAKILEIIDKEVIETQEEIADRLKKAGMEVTQATISRDIKELRLIKVMTEDGRYKYAPFNSTDNTVFNRLMTVFSKSYVSSDYANNIVVVKTLPGMAPAAASAIDSMNYPEIVGSIAGDDTVLIVCRSEKIAKEFVEKLSKLAKSDDK
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_ACHLI
Sequence: MKEKIDSIVKSLNDKIHPDLTLNDLEALRVEYLGKNGILTSQMSLIRTLPNEEKPKFGQWINDAKVAIEQVISDQKNILLTIAMNEQLKKETLDVTMPGLNFKKGSLHPLTLVTQDLEDYFIGLGYKVAEGPELELDKYNFEMMNLASDHPAREMHDSFYVTQNTLLRTHTSPIQARYMEKSKGQPIAIIAPGKTYRRDPDDRTHSHQFMQCEGLVIDKDVTFAHLKETLLGMARHIFGEERTIRLRPSYFPFTEPSVEVDVSYVDSDGKTEWIEVLGAGMVHPNVLTMGGYDPKVYRGFAFGIGLERIAILKYKIDDIRQFYTNDLRFLNQFKGVL
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_LATSS
Sequence: MAQKDNQKEMNDQLKVRREKMQFLKDEGIDPFGSRFERTHLAAALHEEFEAIEKDDLDVKNQEVTIAGRMMSKRGKGKVGFADIRDRSGKIQIYVRKDEVGEDNYKIFKKADLGDHLGITGQIMKTDMGELTVKATHLTFLSKALRPLPDKYHGLTNVEQIYRQRYLDLIANPESMDRFTKRSKIISAVREYLDTHDFTEVETPVLHGQAGGASARPFITHHNALDINLYLRIALELHLKRLIVGGMERVYEIGRVFRNEGIDTKHNPEFTMLETYAAYFDYKDVMDETEGIIRFAAHKVLGTGQISYQGQAIDLDSDFARVHMVDAIKAETGVDFWQPMTVESARELADQHHVKYEEYWQVGHIINAFFEEFVEDTLVQPTFIYGHPVEISPLAKKNAEDDRFTDRWELFMHGNEYANAFTELNDPIDQRERFEAQAKERENGNDEAEGIDEDYVEALEYGMPPTGGLGIGIDRLVMLLTDAASIRDVLLFPTMRPDKQENEEI
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLPA_PYRFU
Sequence: MVEVKKHKFPGVYVVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRIWNPHRSKLGAAIVNGLKNFPIKPGKSVLYLGIASGTTASHVSDIVGWEGKIYGIEFSPRVLRELVPIVEERRNIIPILGDATKPEEYRALVTKVDVIFEDVAQPTQAKILIDNAKAYLKRGGYGMIAVKSRSIDVTKEPEQVFKEVERELSEYFEVIERLNLEPYEKDHALFVVRKP
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: MNHG1_STAA8
Sequence: MIKIILISLALIFVIIGALISALAAIGLLRLEDVYSRAHAAGKASTLGAMSLLFGTFLYFIATQGFVNMQLIVAIIFVLITGPLSSHMIMKAAYNIKTPYTKKTKVDEISEDLKDTKL
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit G1, Mnh complex subunit G1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS2_THIDA
Sequence: MSVTMRQMLEAGVHFGHQTRFWNPRMAPFIFGHRNKIHIVNLEKSLPMFQEAQKFVRQLSANKGNVLFVGTKRAARDIVREEAQRAGMPYVDQRWLGGMLTNFKTVKQSIKRLNDLEAQIAEPGRLSKKEILTVQREVDKLNRSLGGIREMGGLPDALFIIDVGYQKGAVVEAKKLGIPVIGVVDTNNSPEGVDYVIPGNDDSARAIRLYARGMADAALEGRAQVISEIVGGEEFVEVEEEEGGVAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL5_SULAC
Sequence: MSMQEAKKENVMRRVVLDKVTVNIGVGESGERLQKAYQLVQELTGVKPVYTKGRKSIREFGVRKGAPIGVKATLRRQAAVEFLKKVLPAVNFRLKQSSFDNYGNVSFGIAEHVLIPGTRYDPEIGIFGMDVAITLVRPGYRTMKRKRKKASIPRRHRVTKEEAINFMKENFNVTILEG
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GASAD_ARATH
Sequence: MATKLSIIVFSIVVLHLLLSAHMHFLINVCAECETKSAIPPLLECGPRCGDRCSNTQYKKPCLFFCNKCCNKCLCVPPGTYGNKQVCPCYNNWKTKSGGPKCP
What is the function of this protein?
Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination, flowering and seed maturation.
What are the official names of this protein?
Gibberellin-regulated protein 13, GAST1 protein homolog 13.
What is the protein family that this protein belongs to?
Belongs to the GASA family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRSA_STRPN
Sequence: MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFYEQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAGMTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAKEVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGVSDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIGKELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TBB_COCHE
Sequence: MREIVHLQTGQCGNQIGAAFWQTISGEHGLDGSGVYNGTSDLQLERMNVYFNEASNNKFVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATYSVVPSPKVSDTVVEPYNATLSIHQLVENSDETFCIDNEALYDICMRTLKLNNPSYGDLNHLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVTVPELTQQMFDPKNMMAASDFRNGRYLTCSAYFRGKVSMKEVEDQMRNVQNKNSSYFVEWIPNNVQTALCSIPPRGLKMSSTFVGNSTSIQELFKRVGDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEASVSEGEEEYDEEAPLEAEE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PRA17_HUMAN
Sequence: MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGARALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLAFGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS
What are the official names of this protein?
PRAME family member 17.
What is the protein family that this protein belongs to?
Belongs to the PRAME family.
Protein: PPOX1_ARATH
Sequence: MRNVIRRVTTMTFTFLLQSPPLPISPSPPQFSLSSSPLSKTQRFITPSQGSRLRTLCTKVIIPNMQDSGSPPLSYLTQREAAEIDETLMGPLGFSIDQLMELAGLSVAASIAEVYKPEEYSRVLAICGPGNNGGDGLVAARHLHHFGYKPFICYPKRTAKPLYTGLVTQLDSLSVPFVSVEDLPDDLSKDFDVIVDAMFGFSFHGAPRPPFDDLIRRLVSLQNYEQTLQKHPVIVSVDIPSGWHVEEGDHEDGGIKPDMLVSLTAPKLCAKRFRGPHHFLGGRFVPPSVAEKYKLELPSYPGTSMCVRIGKPPKVDISAMRVNYVSPELLEEQVETDPTVQFRKWFDEAVAAGLRETNAMALSTANKDKKPSSRMVLLKGFDENGFVWFTNYESKKGSDLSENPSAALLFYWEILNRQVRIEGPVERIPESESENYFHSRPRGSQIGAIVSKQSSVVPGRHVLYDEYEELTKQYSDGSVIPKPKNWGGFRLKPNLFEFWQGQPSRLHDRLQYSLQDVNGNPAWKIHRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).  Involved in the PLP salvage pathway.  Has a higher preference for PNP over PMP.  May also catalyze the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase 1, chloroplastic, AtPPOX1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pyridoxamine 5'-phosphate oxidase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MODC1_BRADU
Sequence: MGGFTKEAKKGYIEVAFNGSLASILLDTQFSVPAKGVTAIFGPPGCGKTTLARCIAGVQRLPNGFCAIDGEIWQDETTFRPPHLRRVAYVFQLPILSSHLSVRRTLLYNASNSEPTLIDFDGVVELLGLAPLLERTPSHLSKTERQRLALGSALLGQPRLLLLDDPLIVRDRSAKCEILPFLERILQSLALPMIYISHDITDIERLADHLVMMKDGTVTAAGPLNVTQSDPALASRSEAAICLDTMVGGYDGRYGLVKLRLKSARFLIPAVPLRPGARLRLRIAAGDVSIACEPPRASSILNVFRARITASLPHGDAEVTLVLTLETGHSGVPLLARITRRSFDALRLSIGAEVFAEELCGKLGDDGMR
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NEUR4_MOUSE
Sequence: MGPTRVPRRTVLFQRERTGLTYRVPALLCVPPRPTLLAFAEQRLSPDDSHAHRLVLRRGTLTRGSVRWGTLSVLETAVLEEHRSMNPCPVLDEHSGTIFLFFIAVLGHTPEAVQIATGKNAARLCCVTSCDAGLTWGSVRDLTEEAIGAALQDWATFAVGPGHGVQLRSGRLLVPAYTYHVDRRECFGKICWTSPHSLAFYSDDHGISWHCGGLVPNLRSGECQLAAVDGDFLYCNARSPLGNRVQALSADEGTSFLPGELVPTLAETARGCQGSIVGFLAPPSIEPQDDRWTGSPRNTPHSPCFNLRVQESSGEGARGLLERWMPRLPLCYPQSRSPENHGLEPGSDGDKTSWTPECPMSSDSMLQSPTWLLYSHPAGRRARLHMGIYLSRSPLDPHSWTEPWVIYEGPSGYSDLAFLGPMPGASLVFACLFESGTRTSYEDISFCLFSLADVLENVPTGLEMLSLRDKAQGHCWPS
What is the function of this protein?
Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides.  Efficiently hydrolyzes gangliosides including alpha-(2->3)-sialylated GD1a and GM3 and alpha-(2->8)-sialylated GD3 (PubMed:19506080, PubMed:22393058).  Hydrolyzes poly-alpha-(2->8)-sialylated neural cell adhesion molecule NCAM1 likely at growth cones, suppressing neurite outgrowth in hippocampal neurons (PubMed:19506080, PubMed:22393058).  May desialylate sialyl Lewis A and X antigens at the cell surface, down-regulating these glycan epitopes recognized by SELE/E selectin in the initiation of cell adhesion and extravasation (By similarity).  Has sialidase activity toward mucin, fetuin and sialyllactose (PubMed:19506080, PubMed:22393058).
What are the official names of this protein?
Sialidase-4, N-acetyl-alpha-neuraminidase 4, Neuraminidase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein. Cell projection, neuron projection. Lysosome lumen.
Protein: MIAB_RUTMC
Sequence: MKKLYIRTFGCQMNEYDSNKIADVLNHSHGLVLTDDAASANVLLLNTCSIREKAQEKLFHQLGRWRKLKDKNSNLIIGVGGCVASQEGELILERAPYVDIIFGPQTLHRLPSMLNEVLTPTPGMSVKPSIDISFPEIEKFDHLPKPKTSSVTAFVSIMEGCSKYCTFCIVPYTRGEEVSRPFIDVINEVKILAIQGVREVNLLGQNVNAYQGLMDDGEIADLALLINIAAQIDGIKRIRYTTSHPTQFSDSLIEAYMEVPKLASHLHLPIQSGSDKILRLMKRGHMVIEYKSKIRKLRKIRPDISISSDFIIGFPGENEQDFLDTMTLIDEIGFDKSFSFIYSARPGTLASSYLDDVDMDVKKQRLALVQKTIDKNTERISKSMVGSVQKILVENVAKKRDNLFGRTENMRNTHFKGDKSLIGQIVNIKITQGRGNSLVGNLIA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INT2_ARATH
Sequence: MEGGIIHGGADESAFKECFSLTWKNPYVLRLAFSAGIGGLLFGYDTGVISGALLYIRDDFKSVDRNTWLQEMIVSMAVAGAIVGAAIGGWANDKLGRRSAILMADFLFLLGAIIMAAAPNPSLLVVGRVFVGLGVGMASMTAPLYISEASPAKIRGALVSTNGFLITGGQFLSYLINLAFTDVTGTWRWMLGIAGIPALLQFVLMFTLPESPRWLYRKGREEEAKAILRRIYSAEDVEQEIRALKDSVETEILEEGSSEKINMIKLCKAKTVRRGLIAGVGLQVFQQFVGINTVMYYSPTIVQLAGFASNRTALLLSLVTAGLNAFGSIISIYFIDRIGRKKLLIISLFGVIISLGILTGVFYEAATHAPAISSLETQRFNNISCPDYKSAMNTNAWDCMTCLKASSPSCGYCSSPIGKEHPGACWISDDSVKDLCHNENRLWYTRGCPSNFGWFALLGLGLYIIFFSPGMGTVPWIVNSEIYPLRFRGICGGIAATANWISNLIVAQSFLSLTEAIGTSWTFLIFGVISVIALLFVMVCVPETKGMPMEEIEKMLERRSMEFKFWKKKSKLVEKQNQSA
What is the function of this protein?
Plasma membrane inositol-proton symporter.  Specific for several inositol epimers, such as myoinositol and scylloinositol.  D-chiroinositol, mucoinositol, alloinositol and pinitol are also transported with a lower activity.  Not active with galactinol and phytate.
What are the official names of this protein?
Probable inositol transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYV_STAAB
Sequence: MEMKPKYDPREVEAGRYEEWVKNGYFKPSEDKSKETYTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEKGITRYDLGREKFLEQAWDWKEEYASFIRAQWAKLGLGLDYSRERFTLDEGLSKAVKKVFVDLYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADGEGFIEIATTRPETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIDFGSGAMKVTPAHDLNDFEIGQRHQLENIIVMDENGKMNDKAGKYEGMDRFDCRKQLVEDLKEQDLVIKIEDHVHSVGHSERSGAVVEPYLSTQWFVRMEDLAKRSLDNQKTDDRIDFYPQRFEHTFNQWMENIRDWTISRQLWWGHQIPAWYHKETGEIYVGEEAPTDIENWQQDEDVLDTWFSSALWPFSTLGWPDLESEDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVLLHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVESVWNFINKIWNGARFSLMNIGEDFKVEDIDLSGNLSLADKWILTRLNETIATVTDLSDKYEFGEVGRALYNFIWDDFCDWYIEMSKIPMNGNDEEQKQITRSVLSYTLDNIMRMLHPFMPFVTEKIWQSLPHEGDTIVKASWPEVRESLIFEESKQTMQQLVEIIKSVRQSRVEVNTPLSKEIPILIQAKDKEIETTLSQNKDYLIKFCNPSTLNISTDVEIPEKAMTSVVIAGKVVLPLEGLIDMDKEISRLEKELAKLQSELDRVDKKLSNENFVSKAPEKVINEEKRKKQDYQEKYDGVKARIEQLKA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_BURPS
Sequence: MINRAQLLDTLASQAPRDFEAQALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSPGGSVSAGMAIYDTMQFVKPDVSTLCMGLAASMGAFLLASGAKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLRDRLNHLLAHHTGQDVERIARDTDRDNFMSSEDAKAYGLIDHVSTKRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMT1M_SCHPO
Sequence: MLSTKRLRVLELYSGIGGMHYALNLANIPADIVCAIDINPQANEIYNLNHGKLAKHMDISTLTAKDFDAFDCKLWTMSPSCQPFTRIGNRKDILDPRSQAFLNILNVLPHVNNLPEYILIENVQGFEESKAAEECRKVLRNCGYNLIEGILSPNQFNIPNSRSRWYGLARLNFKGEWSIDDVFQFSEVAQKEGEVKRIRDYLEIERDWSSYMVLESVLNKWGHQFDIVKPDSSSCCCFTRGYTHLVQGAGSILQMSDHENTHEQFERNRMALQLRYFTAREVARLMGFPESLEWSKSNVTEKCMYRLLGNSINVKVVSYLISLLLEPLNF
What is the function of this protein?
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).  Can also methylate cytosine 38 in tRNA(Glu), albeit to a lower level, but not tRNA(Lys).  Pmt1-dependent tRNA methylation is induced by nitrogen limitation and depends on the nutrient-sensing protein kinase sck2.  Does not have DNA-methylation activity.
What are the official names of this protein?
tRNA (cytosine(38)-C(5))-methyltransferase, DNA (cytosine-5)-methyltransferase-like protein 2, Dnmt2, M.SpomI, SpIM.SpoI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BAR1_CHITE
Sequence: RPERCGSAMRKAEAEKCARRNGRFNASKCRCTSAGKPSRNSEPSKGSKPRPEKPSKGSKPRPEKPSKGSKPKPEKPSKGSKPRPERCGSAMRKAEAEKCARRNGRFNASKCRCTSAGKPSRKSEPSKGSKPRPEKPSKESKPRPEKPSKGSKPRPEKPSKGSKPRPEGCGSAMR
What is the function of this protein?
Used by the larvae to construct a supramolecular structure, the larval tube.
What are the official names of this protein?
Balbiani ring protein 1, Giant secretory protein I-A, GSP-IA.
What are the subcellular locations of this protein?
Secreted.
Protein: EVA1A_DANRE
Sequence: MVTAFLNERQATTEEMALVSNALAAYSFIADQPERAALYFVCGVCLGLVLTLIALVVQISCRTDCKTQQAPKKTGKTVENTSDTSDSDSDWDNTSDLSARRHRRFERTLGNVFTSAEELERAQRLEERERIIREIWMNGQPDMPGTRSLNRYY
What is the function of this protein?
Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.
What are the official names of this protein?
Protein eva-1 homolog A, Protein FAM176A, Transmembrane protein 166.
What is the protein family that this protein belongs to?
Belongs to the EVA1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein.