PharMolix/UniProtQA huggingface dataset:
Protein: LOLC_ECO57
Sequence: MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTVLSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVVLQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGDQIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGNITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGALLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQPAEALRYE
What is the function of this protein?
Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane.  Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA (By similarity).
What are the official names of this protein?
Lipoprotein-releasing system transmembrane protein LolC.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TBP_PROFL
Sequence: MDQNNSLPPYAQGLASPQSAMTPGIPIFSPMMPYGTGLTPQPAQSTNSLSILEEQQRQQQQAAAQQSTSQPTQAPSGQTPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRGEIYEAFENIYPILKGFRKTT
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LERL1_HUMAN
Sequence: MAGIKALISLSFGGAIGLMFLMLGCALPIYNKYWPLFVLFFYILSPIPYCIARRLVDDTDAMSNACKELAIFLTTGIVVSAFGLPIVFARAHLIEWGACALVLTGNTVIFATILGFFLVFGSNDDFSWQQW
What is the function of this protein?
Negatively regulates growth hormone (GH) receptor cell surface expression in liver.  May play a role in liver resistance to GH during periods of reduced nutrient availability.
What are the official names of this protein?
Leptin receptor overlapping transcript-like 1, Endospanin-2.
What is the protein family that this protein belongs to?
Belongs to the OB-RGRP/VPS55 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CAZA1_BOVIN
Sequence: MADFEDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSWRESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKVDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.  May play a role in the formation of epithelial cell junctions (By similarity).  Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-1, CapZ alpha-1.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HSSS_STAAE
Sequence: MFKTLYARIAIYSITVILFSALISFVLTNVYYHYNLKASNDAKIMKTLKEARQYEQSAKPTHIQQYFKHLGQMNYQIMTIDQKGHKTFYGEPFREDTLSQNAINNVLNNQDYHGIKDKPFALFVTGFFDNVTDNTVGINFKTKDGSIAVFMRPDIGETFSEFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDGDFETPIKQTRKDEIGTLQYHFNKMRESLGQVDQMRQHFVQNVSHEIKTPLTHIHHLLSELQQTSDKTLRQQYINDIYTITTQLSGLTTELLLLSELDNHQHLLFDDKIQVNQLIKDIIRHEQFAADEKSLIILADLESINFLGNQRLLHQALSNLLINAIKYTDVGGAIDIALQHSHNNIIFTISNDGSPISPQAEARLFERFYKVSKHDNSNGLGLAITKSIIELHHGTIQFTQSNEYVTTFTITLPNNSL
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR.  HssR/HssS activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood.
What are the official names of this protein?
Heme sensor protein HssS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HBB_BOSGF
Sequence: MLTAEEKAAVTAFWGKVHVDEVGGEALGRLLVVYPWTQRFFESFGDLSTADAVMNNPKVKAHGKKVLDSFSNGMKHLDDLKGTFAALSELHCDKLHVDPENFKLLGNVLVVVLARHFGKEFTPVLQADFQKVVAGVANALAHRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MNME_PROM2
Sequence: MDSIVTTEDTIAAIASAISIGKGGVAIIRVSGKDSINSCKKIVQTKSKYAWESHRVFHGFIQENKQNKFIDEVLISVMKSPNSFTGEDVVELHCHGGIIIVNKVLKILLSSNSRVRLANPGEFSQRAFLNGKIDLTQAESINQLINASNTRSAELAFSGIQGEIKKKINDIKNDLINQLCEIEARVDFEEDFTDFDYTKYLKNIKKVKEKIELLIENAKRNSYIHNGISIALIGKTNVGKSSLLNLLAKKEKAIVTNIPGTTRDVIEINLTINDIPMKIIDTAGIRETSEQIERIGIKKSFRKIKESDFIIYIYSLEEGFNEEDKKIIQEIPKEKLITILGNKKDLIDCKNINSNELKNTILMSIKNNDGERLLIDTIIKKCGLKQVENINIFLNERHLANLSACLSNLNDTDEIIKNKLPFDLLSIELRDGIQNLSKITGQELTEELLDNIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_PSET1
Sequence: MISISETAQAHFAKLLADQAQQTNIRVFVVNPGTSQAECGVSYCPEDAVEDSDIRLNFNGFDGVVDAESAPFLEDAEIDFVTDKMGTQLTLKAPNAKARKISGDASLNERVQHMLETEVNPQLANHGGQVSLVEITAAGIAVLQFGGGCNGCSMIDVTLKEGIEKEMIEKFEEITGVADITEHQAGDHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: RPOB_PROM0
Sequence: MSSSALQVAKTATYLPDLVEVQRASFKWFLEKGLIEELQNFSPISDYTGKLELHFIGEEYRLKRPRHDVEEAKRRDATFASQMYVTCRLINKETGEIKEQEVFIGELPLMTERGTFIINGAERVIVNQIVRSPGVYFKDELDKNGRRTYNASVIPNRGAWLKFETDKNNLLYVRVDKTRKINAHVLMRAMGLSDNDVVDKLRHPEFYQSSIESANDEGINSEDQALLELYKKLRPGEPPSVSGGQQLLHSRFFDPKRYDLGRVGRYKINKKLRLTVPDNVRTLTHEDVLSTIDYLINLELDIGGASLDDIDHLGNRRVRSVGELLQNQVRVGLNRLERIIKERMTVGETDSLTPAQLVNPKPLVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRISALGPGGLTRERAGFAVRDIHPSHYGRLCPIETPEGPNAGLINSLATHARVNEYGFIETPFWEVKNGKVDKEGNPVYLSADLEDECRVAPGDVATDKDGNIIANLIPVRYRQDFEKVPPHQVDYVQLSPVQVISVATSLIPFLEHDDANRALMGSNMQRQAVPLLRPERPLVGTGLESQVARDSGMVPITKVNGTVSYVDANEIVVKDEDGNEHFHYLQKYQRSNQDTCLNQRPIVKIGDRVISGQVLADGSACEGGEIALGQNVLIAYMPWEGYNYEDAILVSERMVTDDLYTSVHIEKYEIEARQTKLGPEEITREIPNISEESLNNLDEMGIIRIGAFVESGDILVGKVTPKGESDQPPEEKLLRAIFGEKARDVRDNSLRVPKTEKGRVLDVRIYTREQGDELPPGANMVVRVYVAQRRKIQVGDKMAGRHGNKGIISRILPREDMPYLPDGTPVDIVLNPLGVPSRMNVGQVFELLMGWAAANLNCRVKVVPFDEMYGAEKSHQTVQAFLEEASKQPGKAWVYNPDDPGKLLLKDGRTGEPFDQPVAVGYSHFLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRLGEMEVWALEAYGAAYTLQELLTVKSDDMQGRNEALNAIVKGKPIPRPGTPESFKVLMRELQSLGLDIGVYTDEGKEVDLMQDINPRRNTPSRPTYESLGTSEYEED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: YCXJ_NEOYE
Sequence: MNNKSLIFLAIKSLDIQNQISLTSNIFNLSFDIQLNQIIIDSQIKSDKDLKSILLKVLNSIGNQSLDSNDLANNYKRRFRYYFSKMSFFRSLEKSIYENNILIDNLGITGLYLLYLIVEKEDVFKLWLYYKNYTFDQLIRLIETKNNFYN
What are the official names of this protein?
Uncharacterized protein ORF148.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: S38A6_XENTR
Sequence: MQASDSSINTLDGHQVSAGRDESTPLLANSPQRRSSGGTSFGFAVFNLMNAIMGSGILGLSYAMAKTGILGFSALLLIVALLAAYSIHLLLRMCLLTAVTSYEDLGLYAFGRSGKVLVACTILIQNVGAMSSYLFIIKSELPAAIASFLPGAQGEPWYLDGRTLLIITSVCIVLPLALLPKIGFLGYTSSLSFFFMVYFAVVIVIKKWNIPCPLPPLNHTVTFLQAPNISECKPKLFDFSKESAFALPTMAFSFLCHTSVLPIYCELKSPSKSKMQNVANVGIALSFLIYYISALFGYLTFYDNVKSELLQGYSKYLPKDVLIITVRLCILLAVLLTVPLIHFPARKAVMMMFFSRYPFSYIRHILVTLVLNIIIVLLAIYVPDMRSVFGVVGSTTSTCLLFVFPGLFYVKLGREDCSSPQKFGACGLLVLGICIGACSLTLIIMNLA
What is the function of this protein?
Probable sodium-dependent amino acid/proton antiporter, could be a neuronal transporter for glutamate.
What are the official names of this protein?
Probable sodium-coupled neutral amino acid transporter 6, Na(+)-coupled neutral amino acid transporter 6, Solute carrier family 38 member 6.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PETL_MARPO
Sequence: MLTIISYFLFLIGALTLALVLFIGLNKIQLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: EMIL1_MOUSE
Sequence: MAPRALWSCYLCCLLTIATEAASYPPRGYSLYTGGTGALSPGGPQAQNSPRPASRHRNWCAYVVTRTVSCVLEDGVETIVKPDYQPCGWGQPHCSRSIMYRSFLRPRYRVAYKTVTDMEWRCCQGYGGDDCGEGPASVLGPAPSTPLPRPRPVRPNLSGSSAGSHLSGLGGEGPVESEKVQQLERQVKSLTKELQGLRGVLQGMNGRLAEDVQRAVDTVFNGRQQPADAAARPGVHETLSEIQQQLQLLDNRVSTHDQELGHLNNHHNGGPGGGGRASGPVPVPSGPSEELLRQLERQLQESCSVCLTGLDGFRQQQQEDRERLRTLEKLMSSMEERQQQLVGPAMARRPPQECCPPELGRRVSELERRLDVVTGSLTVLSGRRGSELGGAAGQGGHPPGYTSLASRLSRLEDRFNSTLGPSEEQEKNWPGGPGRLGHWLPAAPGRLEKLEGLLANVSRELGGRMDLLEEQVAGAVRTCGQICSGAPGEQDSRVNEILSALERRVLDSEGRLQLVGSGLHEAEAAGEAQQAVLEGLQGLLSRLRERMDAQEETAAEILLRLNLTAAQLSQLEGLLQARGDEGCGACGGVQEELGRLRDGVERCSCPLLPPRGPGAGPGVGGPSRGPLDGFSVFGGSSGSALQALQGELSEVILTFSSLNDSLHELQTTVEGQGADLADLGATKDSIISEINRLQQEATEHVTESEERFRGLEEGQAQAGQCPSLEGRLGRLEGVCERLDTVAGGLQGLREGLSRHVAGLWAAVRESNSTSLTQAALLEKLLGGQAGLGRRLGALNNSLLLLEDRLQQLSLKDFTGPSGKAGPPGPPGLQGPSGPAGPPGPPGKDGQQGAIGPPGPQGEQGAEGAPAAPVPRVAFSAALSLPRSEPGTVPFDRVLLNDGGYYDPETGVFTAPLAGRYLLSAVLTGHRHEKVEAVLSRSNLGVARIDSGGYEPEGLENKPVAESQPSPGALGVFSLILPLQVGDTVCIDLVMGQLAHSEEPLTIFSGALLYEDTELEQV
What is the function of this protein?
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly.  Has cell adhesive capacity (By similarity).  May have a function in placenta formation and initial organogenesis and a later role in interstitial connective tissue.
What are the official names of this protein?
EMILIN-1, Elastin microfibril interface-located protein 1, Elastin microfibril interfacer 1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Found mainly at the interface between amorphous elastin and microfibrils.
Protein: 3DHQ_TALMQ
Sequence: MPTILILNGPNLNLLGLREPHIYGSTTLQDVENICIELGKQHNVTVDAFQSNHEGQLIDRIHEARNKVDLIVINPAAYTHTSVAIRDALLGVSIPFIEVHISNVHAREQWRHHSYFSDKAVACIVGLGTFGYEAAIQHATLKQFKDLTFRYKRGDYGEVIYYYESLPNPILVVVL
What is the function of this protein?
Is involved in the catabolism of quinate.  Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.
What are the official names of this protein?
Catabolic 3-dehydroquinase, cDHQase, 3-dehydroquinate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: AMBP_MOUSE
Sequence: MQGLRTLFLLLTACLASRADPASTLPDIQVQENFSESRIYGKWYNLAVGSTCPWLSRIKDKMSVSTLVLQEGATETEISMTSTRWRRGVCEEITGAYQKTDIDGKFLYHKSKWNITLESYVVHTNYDEYAIFLTKKSSHHHGLTITAKLYGREPQLRDSLLQEFKDVALNVGISENSIIFMPDRGECVPGDREVEPTSIARARRAVLPQESEGSGTEPLITGTLKKEDSCQLNYSEGPCLGMQERYYYNGASMACETFQYGGCLGNGNNFISEKDCLQTCRTIAACNLPIVQGPCRAFIKLWAFDAAQGKCIQFHYGGCKGNGNKFYSEKECKEYCGVPGDGYEELIRS
What is the function of this protein?
Kunitz-type serine protease inhibitor.  Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation.  Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
What are the official names of this protein?
Protein AMBP.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
[Alpha-1-microglobulin]: Secreted. Endoplasmic reticulum. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Nucleus membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Secreted, extracellular space, extracellular matrix. Note=The cellular uptake occurs via a non-endocytotic pathway and allows for localization to various membrane structures. A specific binding to plasma membrane suggests the presence of a cell receptor, yet to be identified. Directly binds collagen fibers type I.
Protein: LSPA_STRAW
Sequence: MAEAERIIGTPDIPEAAGAEPEQADGESGGAGAGTERPKGRRRIAVLFAVAALAYAFDLVSKLIVVAKLEHHAPIEIIGDWLRFEAIRNAGAAFGFGEAFTVIFTVIAAAVIVVIARLARKLYSLPWAIALGLLLGGALGNLTDRIFRSPGVFEGAVVDFIAPKHFAVFNLADSAIVCGGILIVLLSFRGLDPDGTVHKD
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCD_KORVE
Sequence: MAIKSDRWIRRMAQEHDMINPFYEKQMRQGVISYGLSSYGYDLRVADEFKIFTNVNNAIVDPKHFDEKSFVTITSDVCIVPPNSFALARSVEYFKIPRDVLTICVGKSTYARCGIIVNVTPFEPEWEGYVTLEISNTTPLPAKIYANEGLCQILFFQSDEVCEISYKDKKGKYQSQKGIVLPKL
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CAD15_MOUSE
Sequence: MGSALLLALGLLAQSLGLSWAVPEPKPSTLYPWRRASAPGRVRRAWVIPPISVSENHKRLPYPLVQIKSDKQQLGSVIYSIQGPGVDEEPRNVFSIDKFTGRVYLNATLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQDVFRGRILEGAIPGTFVTRAEATDADDPETDNAALRFSILEQGSPEFFSIDEHTGEIRTVQVGLDREVVAVYNLTLQVADMSGDGLTATASAIISIDDINDNAPEFTKDEFFMEAAEAVSGVDVGRLEVEDKDLPGSPNWVARFTILEGDPDGQFKIYTDPKTNEGVLSVVKPLDYESREQYELRVSVQNEAPLQAAAPRARRGQTRVSVWVQDTNEAPVFPENPLRTSIAEGAPPGTSVATFSARDPDTEQLQRISYSKDYDPEDWLQVDGATGRIQTQRVLSPASPFLKDGWYRAIILALDNAIPPSTATGTLSIEILEVNDHAPALALPPSGSLCSEPDQGPGLLLGATDEDLPPHGAPFHFQLNPRVPDLGRNWSVSQINVSHARLRLRHQVSEGLHRLSLLLQDSGEPPQQREQTLNVTVCRCGSDGTCLPGAAALRGGGVGVSLGALVIVLASTVVLLVLILLAALRTRFRGHSRGKSLLHGLQEDLRDNILNYDEQGGGEEDQDAYDINQLRHPVEPRATSRSLGRPPLRRDAPFSYVPQPHRVLPTSPSDIANFISDGLEAADSDPSVPPYDTALIYDYEGDGSVAGTLSSILSSLGDEDQDYDYLRDWGPRFARLADMYGHQ
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
What are the official names of this protein?
Cadherin-15, Cadherin-14, Muscle cadherin, M-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: UNG_SULDN
Sequence: MIDLKIESSWREVLLDEFQKPYFNSLKEFLVGEKQKYTLYPHSSNIFAAFESTPFESVKVVILGQDPYHGVNQAHGLAFSVNDGVPPPPSLCNIFKELHDDIGCEIPKSGNLMSWAKEGVFLLNTVLSVRASEANSHKNRGWEVFTDTVIRLLSEKKENLVFILWGAPAGAKASLIDEKKHLILKAPHPSPLSSYRGFFGSKPFSKTDEYLISKGLKPVEWCI
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_STRP8
Sequence: MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISEIEDAFDIQIETEEGLNTVGDLVAYVEEKSK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGPRT_STRP6
Sequence: MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKGSVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDIIDTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDYAENYRNLPYVGVLKEEVYSK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIGM2_REOVL
Sequence: MARAAFLFKTVGFGGLQNVPINDELSSHLLRAGNSPWQLTQFLDWISLGRGLATSALVPTAGSRYYQMSCLLSGTLQIPFRPNHRWGDIRFLRLVWSAPTLDGLVVAPPQVLAQPALQAQADRVYDCDDYPFLARDPRFKHRVYQQLSAVTLLNLTGFGPISYVRVDEDMWSGDVNQLLMNYFGHTFAEIAYTLCQASANRPWEHDGTYARMTQIILSLFWLSYVGVIHQQNTYRTFYFQCNRRGDAAEVWILSCSLNHSAQIRPGNRSLFVMPTSPDWNMDVNLILSSTLTGCLCSGSQLPLIDNNSVPAVSRNIHGWTGRAGNQLHGFQVRRMVTEFCDRLRRDGVMTQAQQNQIEALADQTQQFKRDKLEAWAREDDQYNQANPNSTMFRTKPFTNAQWGRGNTGATSAAIAALI
What is the function of this protein?
Inner capsid (core) component.
What are the official names of this protein?
Inner capsid protein sigma-2, Sigma2.
What is the protein family that this protein belongs to?
Belongs to the orthoreovirus sigma-1 protein family.
What are the subcellular locations of this protein?
Virion. Note=Found in the inner capsid (150 copies).
Protein: NADK_LEGPL
Sequence: MKRKFKRAILYARQHRANQEVNESLHRLVDFLSTQDIEIFQDSDTAASFELKAPVLPREKMGAKHDLIIVVGGDGSLLSASRMAIKVNAPVIGINRGRLGFLTDILPQDIESHLGPVLNGQYNEEERFLLHTKIYDKENSYFEGDALNDVVLGRGSETHLIEFDVYINQQLVSHYRSDGMILSTPTGSTAYALSAGGPIMHPQLNAIVLVPMFSHSLSSRPLVIDGEAEIELYISKSNETDLRISCDGHESRVVKPGQKVAVKKNGNRLRLLHPLDYHYYDTLRSKLGWESKHQG
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1482_BACMK
Sequence: MKVVAVTGYKPFELGIFKNDHPGVECIKKALRRKLTVFVEEGLEWVIISGQLGVELWAAEVVFEIQVEYPNLKLAVFTPFLEQEENWKEDNREYYEFILSQADHIDSITKRKYESPEQFKLKNQFFIEKSDALLAVYDEEKSGSPKYIVEAAKKKGEIENYHSYFILFSDLQDIMEEEQWNNAE
What are the official names of this protein?
UPF0398 protein BcerKBAB4_1482.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: DTD_CLOB8
Sequence: MRAVVQRVSSSSVCVDGDIIGEIGVGFNVLIGISKDDTFEDLKYIKDKIINLRVFHDENDKMNLSLLDIKGEILVISQFTLYGDCRKGRRPNFMEAQGGEEAKKLYEEFLDLLKTSNLKVECGEFGADMKVKINNDGPVTILLDSKRNF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHC_YEREN
Sequence: MVEKSIVQEAKDIHLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFSTDWFMTWEQNIHSSMFYNAYSFLLKSGQCTGVEAVIKAYRLYLEQCPDQSGIPPLLALTRAWTLVRFVDSGMLQLSGCNCCGGTFITHAHQPRNSFVCSLCQPPSRAVKKRKLSPQSADITSQLLDEQVRRAV
What is the function of this protein?
Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways (Probable).
What are the official names of this protein?
Flagellar transcriptional regulator FlhC.
What is the protein family that this protein belongs to?
Belongs to the FlhC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_PSEA6
Sequence: MNQNADFCINNVNIATMRSTKQTENDPYGIRENACIFIKNGLIDAIEPAKRRLSSTIKTFDAQRKWLLPGLIDCHTHLVFAGNRALEFEMRQQGMSYAQIAQRGGGIRSTVNATRLASYEGLLNSAIGRAARLVEEGVTTIEIKSGYGLDLATELRMLQVAKDIESYLLVNIQPTYLGAHSVPFEFHEDPDAYVDFVCEHVMPEVIKQGIATSVDVFCESIAFSPVQCEKVFRSAKHYGLNIKAHVEQLSDLKGARLAAKFNALSVDHIEYLPPDDVPAIAKSNTVAVLLPGAFYHLRETQRPPLTALRRHHVPIALASDLNPGSSPVASLLTIMNMGCILFGMTPAEALSGVTRNAAQALGLAQKGQISSGFDADMCLWDIQHPNELSYGINQIRPTRVWVNGKER
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.