PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_IDILO
Sequence: MSQGKVVQIIGAVVDLEFPQDAVPKVYDALKVTEGGLEGLVLEVQQQLGGGIVRAIAMGTTDGLRRGITAKNTGESIMVPVGKKTLGRIMDVLGNPIDEAGPIGEEEKMSIHRAAPSYEEQSNTNELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMNDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTIAEKFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLNRDIASLGIYPAVDPLDSTSRQLDPQVIGDEHYDTAMGVQEVLQRYKELKDIIAILGMDELSEEDKLSVSRARKIQRFLSQPFFVAEVFTGAPGKYVSLKDTIAGFKGILDGDYDDMPEQAFYMVGTIEEAVEKAKNL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYW_CHLPN
Sequence: MNKKKRVLTGDRPTGKLHLGHWVGSIKNRLELQNSPEYDCFFIIADLHTLTTKIRKEEVLDVDNHIYEVLADWLSVGIDPTKSIIYLQSAIPEIYELHLLFSMLISINRVMGIPSLKDMARNASIEEGSLSYGLIGYPILQSADILLAKAQFVPVGKDNEAHVELTRDIARNFNRLYGQVFPEPEVLQGELTSLVGIDGQGKMSKSANNAIYLSDSDATITEKVRKMYTDPNRIRATTPGRVEGNPLFIYHDIFNPHKDEVEEFKARYRQGCIKDIEVKARLAEELIHFLKPIKERRSEFLSKPLALQNVLEDGTHKMREVAKVTMEEVHDKFGFSHKWRSLLK
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_TRIV2
Sequence: MTTLQVASSLNDIAQQTRQAASLLAMLSTEAKNQAIAAVAQALESAKEEILQANIADCEAATAEGIAKPLYKRLQLDEHKLRDAIAGVRDVGKLADPIGQVQIQRELDTGLVLKRITCPLGVLGIIFEARPEAAIQIISLAIKSGNGVILKCGKEAVRSCEAIVKAVKQGLSTTDVNPDVVQLLTTREETLELLRLDKYVDLIIPRGSNSFVRFVQENTRIPVLGHADGICHVYIDKSADIEKAIAVSVDAKVQYPAACNAIETLLVHHSIAAEFLPKVAQALAERQVELKGDERTLQILPEIAAATAIDWETEYSDFILSIKIVDSLTEAIAHINQYGSRHTDAIITEDVAAVETFFGLVNSAGVFHNCSTRFADGFRYGFGAEVGISTQQMPPRGPVGLEGLVTYKYQMTGTGHIVATYTGENAKPFTHQDF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_LEPCP
Sequence: MDKLLIRGGRPLMGEVTISGAKNAALPELCAALLCPEPLTLANVPRLQDVGTTLKVLRHLGVEAERSAVLPDQVRLDATRITTREAPYELVKTMRASILVLGPLLARFGEARVSLPGGCAIGSRPVDQHIKGLQAMGAQIVVEHGYIVARAERLKGARITTDMVTVTGTENLLMAATLADGETVLENAAQEPEITDLAELLIAMGAQIEGQGTHRIRIQGVERLHAPAVPHQIIPDRIETGTFLCAVAATGGDVTLRRTRADHLDAVLDKLREACTELECGADWIRVRAAGRPKGVNLRTSEYPAFPTDMQAQFMALNCIAQGTSRVIETIFENRFMHVNELVRLGAHIAVDGHTAIVEGIARLSGATVMATDLRASASLVIAGLVAEGETTVERIYHLDRGYDQMETKLRGIGADIERIK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_CAMJD
Sequence: MLTKRIIACLDVKDGRVVKGTQFKNHKDMGDIIELARYYSQNGIDELVFYDIAASARKERISREWVSEVAKNINIPFCVAGGIKSEEDAAELLANGADKISINSPALNDPSLITRLAKSFGVQCVVVGIDSFKDENGNLKVFQYTGDEKTSKHSGKSTLEWVKEVQDLGAGEIVLNMMNQDGVKNGYDLEQLEAVYKICKIPLIASGGAGKMEHFLEAFKLGIDGALAASVFHQKLIDIKELKIYLKNQGLSIRI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_AYWBP
Sequence: MSKCYITGKTTLFGNRRSHAMNATKRIWKANLQNVKIIDENGKIQKVKISARALKKLKLQRA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NDMMS_EUBBA
Sequence: MKKRGKGVGSMWYGIGNTGLPNPAAAFVEIHGDGSANVMFGAADIGQGSGTAMAQIAAEELGLDYEKIHVTWGDTMVTPDGGATSASRQTLITGNAVILACRQAKETLAKTAAEKLDCAPEELSFRDNTVFITADPERSMTYGELMAAMKAAGRMAVGAGSYNPNTTGLAPENMSGIPFEVYSYATTIAEVEVDTETGEVDVLKVVSAHDVGTPINRSMVEGQIEGGVTMGQGFVLMEEIEVNTKNGAIKNPSMSKYIIPSNRDVPEIHSILVESEGGPGPFGAKGVGEPALIPMIPAVVAAIEDALGTRFTHTPIMPKDIVAAVKAQEK
What is the function of this protein?
Catalyzes the hydroxylation of nicotinate to 6-hydroxynicotinate.  Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs.
What are the official names of this protein?
Nicotinate dehydrogenase medium molybdopterin subunit, NDH, Nicotinic acid hydroxylase medium molybdopterin subunit, NAH.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
Protein: PUR7_YERE8
Sequence: MQKLAELYRGKAKTVYTTENPDLLVLEFRNDTSALDGQRIEQFDRKGMVNNKFNHFIMAKLEEAGIPTQMESLLSDTEVLVKKLEMIPVECVIRNRAAGSLVKRLGIEEGLELNPPLFDLFLKNDAMHDPMVNESYCKTFGWATEAQLARMKELSYLANDVLSKLFDDAGLILVDFKLEFGLFNGEVVLGDEFSPDGSRLWDKKTLNKMDKDRYRQSLGGLIEAYEEVAHRIGVKLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: OGT_PYRAE
Sequence: MICSQYGPVVVGWDGSKTFVNPSRCSKRVGLAEFLELINIDEIDKRLLYLLGIPRGYVTTYKLYAEVLGTSPRHVGWLMARNPLPVILPCHRVVKSDFSLGGYTGGVEVKKKLLAYEGALCGDRPCRVVRPRMIDDVRDALFKSLGLA
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_METBU
Sequence: MDIIQAKDIIIDFIGTKLEGTGIEGAVVGISGGIDSALVAYLSVEALGAENVLGIHMPEASTPKSEIEDASKVAEALGIDFKVINITNVLEVYRTAMPDIDGASAHVDGNLKARIRMSMLYYYANMFGRVVMGTGNKSEILLGYFTKYGDGGVDIEPIGDLYKTEVREMSKMLGVPESILEKAPSAGLWEGQTDEDDLGVTYETIDKVLQPILAGEGQERVHLKLGVPMEEISSILLRVRSNLHKRTTPQIAYLDDLRGDWLS
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: RUTC_CAUSK
Sequence: MPKTVIIPPGTGTPIAPFSPGTLADGIVYVSGTLAFDKDNNVANPDDAEAQTRQVLETIKSVIETAGGTMDDVTMNHIFLTDWSNYQTINKVYAEYFPGDKPARYCIQCGLVKPGFVVEIASVAHIGKT
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: TRHO_CORDI
Sequence: MAQSKILLYYKFTPIADPKAMMLWQRDMCELLGLKGRILISEHGINGTVGGDMDACKRYVRKMREYPGFRGTEFKWSDGGAEDFPKLSVKVRDEIVAFGAPGELKVDEKGVIGGGVHLKPEEVNKLVEERGDDVVFFDGRNAMEAQIGKFKNAVVPDVRTTHDFIRELESGKYDWMKDKPVVSYCTGGIRCEILSSLMKNRGFKEIYQIDGGIVRYGEKYGNDGLWEGSLYVFDRRMHMEFGNGVQDPGFIQLGHCVQCGAPTNKFEHCINEDECRELVLMCPDCYENPATRNCGREHCKEVAAEAAAAAAV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: HEM6_SHIFL
Sequence: MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCQPFGEDVYPRYKKWCDDYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWG
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFV_KLEPN
Sequence: MERVLINDTTLRDGEQSPGVAFRTSEKVAIAEALYAAGITAMEVGTPAMGDEEIARIQLVRRQLPDATLMTWCRMNALEIRQSADLGIDWVDISIPASDKLRQYKLREPLAVLLERLAMFIHLAHTLGLKVCIGCEDASRASGQTLRAIAEVAQNAPAARLRYADTVGLLDPFTTAAQISALRDVWSGEIEMHAHNDLGMATANTLAAVSAGATSVNTTVLGLGERAGNAAAWKPSALGLERCLGVETGVHFSALPALCQRVAEAAQRAIDPQQPLVGELVFTHESGVHVAALLRDSESYQSIAPSLMGRSYRLVLGKHSGRQAVNGVFDQMGYHLNAAQINQLLPAIRRFAENWKRSPKDYELVAIYDELCGESALRARG
What is the function of this protein?
This protein is a Fe-Mo-cofactor biosynthetic component.
What are the official names of this protein?
Homocitrate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: NUOB_AQUAE
Sequence: MVAINSNGFVTTTVEELLRWGRRNSLWPVTIGLACCAIEMMHTAASRFDLDRLGVIFRASPRQADVLIVAGTVVNKVAPMLKLIWDQMPDPKWCISMGGCASAGGPFPTYSTLQGVDRIIPVDVYIPGCPPTPQGLIYGILQLQRKIKEQGITKYDKLFADFNREIEKEGIFVPRELKV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KHSE_BURPS
Sequence: MAVFTAVSDADLALWMRHYDLGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFENLTAGQLPFYVDLMSHLAKHGVPVPAPVARDDGTLFGELHGKPAAIVTKLEGAAQLAPGVEHCVEVGQMLARMHLAGRDYPRHQPNLRSLPWWRDTVPAIAPFVTGEQRALLEGELAHQAAFFASDDYAALPEGPCHCDLFRDNALFAHAEPDTGHSVRLGGFFDFYFAGCDKWLFDVAVTVNDWCVDLPTGALDAARADALLRAYQTVRPFTAGERRHWGDMLRAGAYRFWVSRLYDFHLPRAAQMLKPHDPGHFERILRERIAHAGALPETHACN
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: METK1_TOBAC
Sequence: METFLFTSESVNEGHPDKLCDQVSDAILDACLEQDPESKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRGIGFTSADVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKKPEEIGAGDQGHMFGYATDETPELMPLTHVWATKLGAKLTEVRKNKTCPWLRPDGKTQVTVEYKNDNGAMVPIRVHTVLISTQHDETVTNDQIAQDLKEHVIKPVIPSQYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVASGLARRCIVQVSYAIGVAEPLSVFVDTYKTGTIPDKDILTLIKENFDFRPGMMSINLDLLRGGNFRYQKTAAYGHFGRDDPDFSWETVKVLKPKA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBA1C_CRIGR
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSAEGDDEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1C chain, Alpha-tubulin 3, Alpha-tubulin III, Tubulin alpha-3 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CRL_YERPP
Sequence: MTLTSAHPKSKLMKRFAALGPYLREGQCQNDHFFFDCLAVCINVKLAPEKREFWGGWIELEPSAGRFTYVYQLGLFNKEGNWNAEKISDPEVQDKLESTLRSFHLRLEEMLASIDMKLEPAADFNDQPVKLSA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGE_PECAS
Sequence: MKMNLPPFIELYRALIATPSISATDSALDQSNHTLINLLAGWFGDIGFHVEVQPVPGTLNKFNMLARIGEGKGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDIDPTKLTKPLYVLATADEETTMAGAKYFSESTQIRPDCAIIGEPTSLQPVRAHKGHMSNAIRIQGQSGHSSDPSRGVNAIELMHEAISHLLVLRNTLQERYHNPIFHIPYPTMNLGHIHGGDAANRICGCCELHMDIRPLPGITLNDLDGLLSEALAPVSQRWPGRLTISELHPPIPGYECPPDHRLISVVENLLGTKTEIVNYCTEAPFIQTLCPTLVLGPGSIEQAHQPDEYIDTAFIKPTRELISQVIHHFCHH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMO_STAAN
Sequence: MWNKNRLTQMLSIEYPIIQAGMAGSTTPKLVASVSNSGGLGTIGAGYFNTQQLEDEIDYVRQLTSNSFGVNVFVPSQQSYTSSQIENMNAWLKPYRRALHLEEPVVKIIEEQQFKCHIDTIIKKQVPVCCFTFGIPNESIIERLKEANIKLIGTATSVDEAIANEKAGMDAIVAQGSEAGGHRGSFLKPKNQLPMVGTISLVPQIVDVVSIPVIAAGGIMDGRGVLASIVLGAEGVQMGTAFLTSQDSNASELLRDAIINSKETDTVVTKAFSGKLARGINNRFIEEMSQYEGDIPDYPIQNELTSSIRKAAANIGDKELTHMWSGQSPRLATTHPANTIMSNIINQINQIMQYK
What is the function of this protein?
Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates.  Acts on propionate 3-nitronate (P3N), the presumed physiological substrate.  Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.
What are the official names of this protein?
Probable nitronate monooxygenase, NMO, Propionate 3-nitronate monooxygenase, P3N monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the nitronate monooxygenase family. NMO class I subfamily.
Protein: OFOA_SACSO
Sequence: MRISWMIGGAQGSGVDTSANIFGNAVAASGYYIYGNREYYSNIKGRHSYFNLTISDKPPRSIAQQIEILTSFDAETIFQHFNEVKDVLIYSTEVENTKAEQVQSMEPEITEHVVKFLKEKGYGTTVKDVINYLKKEKGVKVIPIDYMEILKKVADQAKVQLSVADRARNTIAIAASYKLLGLKEQYLINSITRTFRQEVFAKINTIAAQLAMQQIQPMYNLPELPNNEEKINLDGNTAAAIGKIYGGLRFQSYYPITPASDESVFIEAHQTVFTVDPKTGEKRKSTIVVVQAEDELAAINMASGAALTGVRAATATSGPGFSLMVEGMGWAGMNEVPVVITYYIRGGPSTGQPTRTSQADLMFALNAGHGEFPRIVIASGDHVEAFHDGTWALNLAQKYQTPVIHLVDKALANSYSIIPKKTLGMENIRIEKGKIVINTNTPELKRFEITEDGISPFAPLGTARVHYTGDEHDEYGFIAEASENREKMYEKRIKKLMTADKEIPEESRVNVYGNTDSKVAIITWGSPKGAILDAMEELENEGIKPMLIQIRMFSPFPKNLMRKLLNGKEFIIDVESNYFGQAGEVLKLNTGIEPTHYILKWNGRPMMRDEVKEGIKAVVQKGERRVVLHGGA
What is the function of this protein?
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
What are the official names of this protein?
2-oxoacid:ferredoxin oxidoreductase subunit alpha, OFOR.
Protein: PRMA_STRPM
Sequence: METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKDRFGELYPDVEQSDMIAIIAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQELAEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKMSLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQGTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLIKKEGYLILSGIISEKLDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_STRMU
Sequence: MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLAILDSYVIGQDRAKRALAVAVYNHYKRISFTESQDDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTKNILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKIDDQSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKILTEPKNALVKQYQTLLSYDGVELEFDQEALQAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKKAVEGTDKPILETAS
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: TGT_BUCAP
Sequence: MKFQVISQDKEARHGMFNFNGNIIETPVFMPVGTYGTVKSLNIEEIKNTGSKIILSNALHLYLRPGQDIIKLHGSLHNFMNWNGPILTDSGGFQIFSLSNFCRIKEEGVIFKNHINGKKFFLTPELSMEIQIDLGSNIIMIFDECIAYNKDWEKTKFAMERSLNWSRRSRIHFDLKKKNKKNLLFGIIHGGSYKSLRDISLKELIKMDFDGYALGGLAVGESKLEMHDLLDHITPQIPKKKPRYLMGVGKPEDLIESVYRGIDMFDCVLPTRNARNGHLFVTNGIIKIRNAKYKKDLSVLDKKCTCYTCQNYSRSYLHHLDSCNEILGARLNTIHNLHYYQTLMFNIRNAIKQKKFDEFVSNFYNQKK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: MIAA_SHESM
Sequence: MGPTASGKTALALELAEKHNCEIISVDSALIYRGMDIGSAKPSAEELARGPHRLIDIRDPAESYSAADFRADALREIEQIISMGKTPVLVGGTMMYFKALLEGLSPLPSADEAIRADIQAEADANGWEALHEQLREIDPVSAERIHPNDPQRLSRAIEVYRISGKSLTELTQTKSAPLPYDVVQFAIAPRERKVLHELIGQRFRIMLEQGFIDEVAQLKARGDLHLDLPSMRCVGYRQCWQYLDGEFDYDTMVEKAVAATRQLAKRQLTWLRSWPELNWLESGAEGNLVTLMRQCR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SRGEF_HUMAN
Sequence: MEREPSASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEVSCGSEHNLAIIGGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSSSGLLVGCGAGHSLALCQLPAHPALVQDPKVTYLSPDAIEDTESQKAMDKERNWKERQSETSTQSQSDWSRNGGL
What is the function of this protein?
Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.
What are the official names of this protein?
Secretion-regulating guanine nucleotide exchange factor, Deafness locus-associated putative guanine nucleotide exchange factor, DelGEF, Guanine nucleotide exchange factor-related protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YR863_MIMIV
Sequence: MTFLIDKMYNILPPELWIKIVDYSGEINLLLVDTNFFELFNLVDAKIDVIEYIVRNNLTDILKYIVVLKTLKHPIINKNFVPTKSLNKLLIDNCEKRRLDIIQYLINIGADINSKKNRAVRLASERGYLEIVKYLVSQGADVRANKDYAVVWASRNGHLEVVKYLVSLGANIKVDDNFAVRWASRNGYIDVVKYLTSQDANIRADNNYAVRLASENGHIDVVKYLVSLGADIRADNNYAIRHASRGGHIEVVEYLVSLGANVKSCNDCAVKFASKNGHLGVVKYLASQGADVRSENDYAFRMASENGHLEVVVYLVRQGVNVRADNNYAVRMASENGYLEIVKFLVSQGANIRSKNDYAIQKASKNGHLEVVEHLVNQGANFKSDYDCAIKLASENGHLEVVKYLVSQDADIRVNNDYAIRWASRNGHIEVVKYLVSQGADIRADNDYAVRMASENGHLEVVKYLVNLGANVKAQNNYAVGWASRNGHIGVVKYLVSQGADVRSGNNCAAIMGF
What are the official names of this protein?
Putative ankyrin repeat protein R863.
Protein: CEDA_SALHS
Sequence: MMKPLRQQNRQIISYIPRVEPAPPEHAIKMDTFRDVWILRGKYVAFVLTGESFQRSPAFSVPESAQRWANQVRQENEIAD
What is the function of this protein?
Activates the cell division inhibited by chromosomal DNA over-replication.
What are the official names of this protein?
Cell division activator CedA.
What is the protein family that this protein belongs to?
Belongs to the CedA family.