PharMolix/UniProtQA huggingface dataset:
Protein: CFA44_HUMAN
Sequence: MKEPDDQDTDGEKSVTSKSDGKKSLRSSKSESRSPVQEDNTFLEDDTDETFTKGEGSYLEEDSDEERLEGSLSSFQYGDLQSTTVPQQTPAPAVEEAEEEVKKKISESFFYDYMELASMPFVTLDSNIPLDLLTLVHSFGYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGKTITTDIEGYMELPDGKVLSGSEWGNMLLWEGGLIKVELCRGTSKSCHNGPINQIMLYEGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVFFFEVERDYKPIGYINTPGPVCQLMWSPMSHPESTLLIICENGYILEAPLPTIKQEEDDHDVVSYEIKDMCIKCFHFSSVKSKILRLIEIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEEPLPEIFIPSTPSPILCGFYSEPGKFWVSLGGYDSGFLYHCEFPPCDESSDFKEQKDEPIDVRYLADTEDNPIQTITFNINKVMMFCGMKNGAIRVYVLNQNDPSLTSLVDYWHFNMHDNNYGCIKSIANSFDDRFLVTAGADGNIFVFNIFSEFMLRKDMKAKVPSPRFGIETEPIPEDIEDPKAYSIENARRKREHDKLMKEVGEIKARKREQIKALRSEFCNLLEMNEKLPKHMQFKRTDFDVDSQIRAEMHRKTAFKIQQVEKELAWEKEKHELGLMKLKNRFRDPLESDTIVVHAILSDHKISSYRLVQPSKYSKFKRASQSERKPSKLDRFEKEGPGRKDSQRDAGGSVTIQEESIIEKGKKFRPKTLSEIIVENQIEKTRKLILKAERAQLKIQQRKKEWEELYKSKPGDDYEDPKDLQAIKEAQVYMGDFNLKTAPDYKIPEHMRINAAKKEEELGHLDSLVHGNKRHMNKCILSLRDLKVAVVEEIQCLVQELKNIQSTLHISKHIPIPKIPQIHPEEVPEKRFQYDEETLLNFKQQQMKSKDEKSPGVEQTGSGGPVGGFLKLSSRKDGDLTTRDSISRSSKASTFSLDIPKCLEFEKAEPTDVELEIMKRDEIKHVYMQQYLVNRIKELVVTFDAELRLLRHQKLKLDTQMKLSDLHHVTLFQEILLLKNFEKQENILQERVNSLDKEEQYMQWKINETLKEMEEKKNEITKLQEQEKALYAGFQAAIGENNKFANFLMKVLKKKIKRVKKKEVEGDADEDEESEESSEEESSLESDEDESESEDEVFDDSICPTNCDVALFELALHLREKRLDIEEALVEEKKIVDNLKKEYDTLSKKVKIVATNLNAAEEALEAYQREKQQRLNELLVVIPLKLHQIEYVVFGEIPSDLSGTLVFSNHALRRLQERIHELQEENSKQQKLNKEWRERRKQLIREKREMTKTIHKMEETVRQLMISKFGRVVNLEALQTLSVNTTLEELKIRKLRKELANAKEMKMWEEKIAQMRWELMMKTKEHTRKLYQMNDLCIEKKKLDSRLNTLQNQQGNAFQGPREADVVAREEVTELIQLQAERISALKEEIALLRRKGSLILPPIQSPREKEIQPADL
What is the function of this protein?
Flagellar protein involved in sperm flagellum axoneme organization and function.
What are the official names of this protein?
Cilia- and flagella-associated protein 44, WD repeat-containing protein 52.
What is the protein family that this protein belongs to?
Belongs to the CFAP44 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: CCNOA_XENLA
Sequence: MVTCSMRCTEEHLLGAPAAFSSGKRKRDSGYSPGDATPGDRGEGGPDWPSAGIKKRVKYSRHRKQRLELRSCDSGVADLYETPSPSPVAPTPTNEPYDSPCTSMPDRLGLQSFSDYGHDCYLFNKSLEDKFLTVNCLKNQPQIKAESRCKLISWLIPVHKHLKLGFESLCLTVNILDRFLACTPVASDCFQLVGVTSLLIACKQVESRPPRVKQLLALCCDAFSREQLCNLECIILLKLCFRIGAPTINFFLQHFSLLRVTSVESPDTELIEATKSMTVARGIAELSLADYAFNAYSPSLVAACCLELADRMLCLRNPIGVRVSGYHQSLIKECVGKIDLLVSLNQDSLHRLLPSQFSVKSIKADN
What is the function of this protein?
Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation.  Acts downstream of mcidas to promote mother centriole amplification and maturation in preparation for apical docking.
What are the official names of this protein?
Cyclin-O protein A.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the apical part of cytoplasm.
Protein: ISK7_HUMAN
Sequence: MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSIYKKYPVVAIPCPITYLPVCGSDYITYGNECHLCTESLKSNGRVQFLHDGSC
What is the function of this protein?
Probable serine protease inhibitor.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 7, Esophagus cancer-related gene 2 protein, ECRG-2.
What are the subcellular locations of this protein?
Secreted.
Protein: MURC_GLAP5
Sequence: MKNFQDKVKKLVAEMRRVNQIHFIGIGGAGMSGIAEVLLNEGYQISGSDIADGAVTQRLAKAGAKVFIGHQAENIEGASVVVASSAINESNPEVAAAKEARIPVIQRAQMLAEIMRFRHGIAIAGTHGKTTTTAMISMIYTEAGLDPTFVNGGLVKSAGKNAHLGASRYLIAEADESDASFLHLQPMVSVVTNIEPDHMDTYGGDFEKMKETYVRFLRNLPFYGLAVMCADDETVMEIAPKVGRQVISYGFSEKADYRIEDYQQTGFQGHYTVVCPTGERIEILLNVPGRHNALNATAALAVAKEEGIANEAILAALADFQGAGRRFDQLGSFIRPNGKVMLVDDYGHHPTEVDVTIKAARQGWENKRVVMVFQPHRYSRTRDLFDDFVQVLSQVDALIMLNVYAAGEAPIVGAESKDLCRSIRNLGKVDPILVSDTSQLGEVLDQIIQDGDLILAQGAGNVSKLSRDLAESWKA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWT2B_ORYSI
Sequence: MDSLYDISCFAAGLAGNIFALALFLSPVTTFKRILKAKSTERFDGLPYLFSLLNCLICLWYGLPWVADGRLLVATVNGIGAVFQLAYICLFIFYADSRKTRMKIIGLLVLVVCGFALVSHASVFFFDQPLRQQFVGAVSMASLISMFASPLAVMGVVIRSESVEFMPFYLSLSTFLMSASFALYGLLLRDFFIYFPNGLGLILGAMQLALYAYYSRKWRGQDSSAPLLLA
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET2b, OsSWEET2b.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DRE2_PARBD
Sequence: MPPSQTPAQGSGRFLLLSPPSLSSHPEKLNAILGLHARESTDLQMLDRLALGLVSLPESTYDVVLLLTGADNTLAETYRLVSRGVLQGVVNSLKPGGKLRNRDNQIWGSGSDSAAGLGSSDGDGGGGEKMSSSEQAFRNEAILAGLVFDDRGELAKPDFGAQQAVPLKLGRKKNLGESAFGNGAVELPASNGVRVTTGATSSTTTTTTTTAAAAAATAATPTTTTTTTINSSTPSGVGFIDFSDDFGVPMVEETQDSDEELIDEEELLGEYDMGRHIVQPPECRPKAGKRRRACKDCTCGLSQKLEAEDRAKRANADKALETLKLRTNDLAEVDFTVQGKVGSCGNCALGDAFRCDGCPYIGLPAFKPGEEVRLLNNDVQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: H16U1_CYRHA
Sequence: MNTVRVTFLLVFVLAVSLGQADKDENRMEMQEKTEQGKSYLDFAENLLLQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENVPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1u, U11-TRTX-Hhn1u, Hainantoxin-XVI-21, HNTX-XVI-21.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CDK7_CARAU
Sequence: MALDVKSRAKLYEKLDFLGEGQFATVYKARDKTTNTIVAIKKIKVGHRTEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLLCFMETDLEVIIKDTSLVLTPANIKAYILMSLQGLEYMHNHWILHRDLKPNNLLLDENGVLKLADFGLAKAFGSPNRVYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGSILAELLLRVPFLAGDSDLDQLTGIFEALGTPTEETWPGMSNLPDYVSFKLFPGTPLEHIFSAAGDDLLELLKGLFTFNPCTRTTASQALKMRYFSIRPGPTPGPQLPRPNSSTEALKEKENLLIGIKRKRDSIEQGTLKKKLVF
What is the function of this protein?
Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription.  Cyclin-dependent kinases (CDKs) are activated by the binding to a cyclin and mediate the progression through the cell cycle.  Each different complex controls a specific transition between 2 subsequent phases in the cell cycle.  Required for both activation and complex formation of cdk1/cyclin-B during G2-M transition, and for activation of cdk2/cyclins during G1-S transition (but not complex formation).  cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex.  CAK activates the cyclin-associated kinases cdk1, cdk2, cdk4 and cdk6 by threonine phosphorylation, thus regulating cell cycle progression.  CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (polr2a), allowing its escape from the promoter and elongation of the transcripts (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 7, 40 kDa protein kinase, CDC2/CDK2,4-activating kinase, Cell division protein kinase 7, P40 MO15.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YLOV_BACSU
Sequence: MSIRTLDGRTFAEMILAGAQNLSQNASAVDALNVFPVPDGDTGTNMNLSMTSGAREVEQMDTDDIGKVGSALSKGLLMGARGNSGVILSQLFRGFSKNIETKKEINALEFAAALQAGVDMAYKAVMKPVEGTILTVAKDAAKKAMILAEKETDITALMTAVTEEAEASLNRTPELLPVLKEVGVVDSGGKGLLCVYEGFLASLKGETVPQKAVLPSLDDMVSAEHHKSAQSMMNTEDIEFGFCTEVMVRLDQTKREFDEGTFRQDLSQFGDSLLVIADESLAKVHIHAEEPGNVLNYAQHYGELIKIKIENMREQHTSIISQESKPADNETPPAKQPYGIVTVAMGEGIADLFKSIGASVVIEGGQTMNPSTEDIVDAVKSVNADTVFILPNNSNIIMAANQAASVVDEQVFVIPAKTVPQGMSALLAFNPDQEAEANEANMLSAIQQVKSGQVTFSVRDTHIDGKDIKKGDFMGILNGTIIGTSENQLSAAKMLLSEMIGEDDEIVTILYGEDASQEEAEQLEAFLSEKYEEIEVEIHNGKQPLYSYIVSAE
What are the official names of this protein?
Uncharacterized protein YloV.
Protein: AROE_BACC1
Sequence: MKQLYGVIGNPIGHSLSPVMHNDAFEHLNMDAHYHAFLVKEEVLGEAVRGLKALGISGFNVTTPHKVAIMDYLDEIDPLAKQIGAVNTVVHKDGKLIGYNTDGIGFVRALQSISSKPLQEKRILLLGAGGASRAIYFSLADVGVKEIDVANRTVDKAKELITACKATVHSVALSLEKATEEQGNYDIIIQTTTIGMHPRVEHTPLQISSLNKGTIVSDIIYNPFETKILCEAKEQGAMIQNGIDMFVYQGALAFEMWTGRTPNIERMKQLVIRKLGG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: PGK_THEAC
Sequence: MDEFFLMNSFDLAGKTVYLRVDINAPVNPLTGEIMGIDRFRAHIDTIRNLRNSKVVIVAHQSRPGKDDFISLRQHAQILSHLLNKRVQFVDQLFGSQVNRAVSEMSDGDIVMLENSRFYSEEVDLTTIESMESSNIVRSLSPLFDYFIIDAFAAIHRAQTTLVGFHRIKPNIAGTLIEREVSMIERFRKIREKPKIAILGGAKIEDSIAVSENFLSRGFVDKILTGGVVANAFLWASGFDIGKKNREFIMKNNGDYEKLLDKCRAILSKYGDKLVMPTDFVMNPSGQRISINEKIPDDQILADIGLDTIVEYSEIIDGARAIFMNGPMGMYEIEDYSSGTREVFTAVAHSKAFKLAGGGHTLSALDKLGLTKMIDHASTGGGALISYLSGETMPVLEALKESKKLFEG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPST1_RAT
Sequence: MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRTGLDIKANKTFTYHKNMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVHKGEFQLPDFLKEKPQTEQVE
What is the function of this protein?
Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
What are the official names of this protein?
Protein-tyrosine sulfotransferase 1, Tyrosylprotein sulfotransferase 1, TPST-1.
What is the protein family that this protein belongs to?
Belongs to the protein sulfotransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: IF2_STRA5
Sequence: MSKKRLHEIAKEIGKTSKEVVEQAQSLGLPVKSHASSVEENDATRIVESFSSSKTKAPTNSVQTNQGVKTESKTVETKQGLSDDKPSTQPVAKPKPQSRNFKAEREARAKAEAEKRQHNGDHRKNNRHNDTRSDDRRHQGQKRSNGNRNDNRQGQQNNRNKNDGRYADHKQKPQTRPQQPAGNRIDFKARAAALKAEQNAEYSRHSEQRFREEQEAKRQAAKEQELAKAAALKAQEEAQKAKEKLASKPVAKVKEIVNKVAATPSQTADSRRKKQTRSDKSRQFSNENEDGQKQTRNKKNWNNQNQVRNQRNSNWNHNKKNKKGKTNGAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAHAKVEVDEADIERFFADEDYLNPDNLTERPPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTVEAINHSKAAGVPIIVAINKIDKPGANPERVISELAEHGVISTAWGGESEFVEISAKFGKNIQELLETVLLVAEMEELKADADVRAIGTVIEARLDKGKGAVATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRVSLENLFDTLKAGEVKSVNVIIKADVQGSVEALAASLLKIDVEGVKVNVVHSAVGAINESDVTLAEASNAVIIGFNVRPTPQARQQADADDVEIRQHSIIYKVIEEVEEAMKGKLDPEYQEKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDGVVIFDGKLASLKHYKDDVKEVGNAQEGGLMIENYNDLKEDDTIEAYIMEEIKRK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSH2D_DANRE
Sequence: MAVPLPNDSSNAAFSWFTEYQRSCILENGVVPEWFHGIISRKAAEEMLMCKPAGYFLIRVSESRVGYTLSYRAEDRCRHFMINVLPDNQFMIVGEKTVYCSLHDLVAFHRRCPILPYNELLTVACEQGGKTNYVELLFPQKKDVSHRQVEWISSSTATNTLQSNISEENQTSQLQNNSTSHPGRLYPSLETEVSALNIQSTDQPTKPVPKPRTVFASKTPAEETPPQLPPRMRLPSRLQTSTEDRSQGLMPVIPDRQQITPNTPNEGRTQQKNQQQKPVVMSLVHIKKKLKKKRSEDHTYEEIAGGLFQKDATSALESINTNVEGLVENDYQELAEHPISDGIPKSSDRNLPVEYRHPPPFAPGY
What is the function of this protein?
May be an adapter protein involved in tyrosine kinase signaling.
What are the official names of this protein?
Hematopoietic SH2 domain-containing protein homolog.
Protein: RL24_BUCAK
Sequence: MAAKIRREDEVIVITGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGFVEKEAAIQVSNIALFNAATGKTDRVGFRFEDGKKVRFFKSNSGTIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: VKT2_CYRHA
Sequence: MGTARFLRAVLLLSVLLMVTFPALLSAEHHDGRVDICRLPSDSGDCLRFFEMWYFDGTTCTKFVYGGYGGNDNRFPTEKACVKRCAKA
What is the function of this protein?
Serine protease inhibitor that inhibits chymotrypsin and blocks voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type U15-theraphotoxin-Hhn1b, U15-TRTX-Hhn1b, Kunitz-type serine protease inhibitor hainantoxin-XI-2, HNTX-XI-2.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 03 (sub-Kunitz) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YGDQ_ECOL6
Sequence: MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQRAHARRLGLAGAMVMRLALLASIAWVTRLTNPLFTIFSQEISARDLILLLGGLFLIWKASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAAVVIAVGVMMFAARSIGDFVERHPSVKMLALSFLILVGFTLILESFDIHVPKGYIYFAMFFSIAVESLNLIRNKKNPL
What are the official names of this protein?
UPF0053 inner membrane protein YgdQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISDB_STAA1
Sequence: MNKQQKEFKSFYSIRKSSLGVASVAISTLLLLMSNGEAQAAAEETGGTNTEAQPKTEAVASPTTTSEKAPETKPVANAVSVSNKEVEAPTSETKEAKEVKEVKAPKETKAVKPAAKATNNTYPILNQELREAIKNPAIKDKDHSAPNSRPIDFEMKKENGEQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGDKKLPIKLVSYDTVKDYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKTEEDYKAEKLLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEDTKKALDEQVKSAITEFQNVQPTNEKMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYWKDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDKEAFTKANTDKSNKKEQQDNSAKKEATPATPSKPTPSPVEKESQKQDSQKDDNKQLPSVEKENDASSESGKDKTPATKPTKGEVESSSTTPTKVVSTTQNVAKPTTASSKTTKDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSQNNKNTQENKAKSLPQTGEESNKDMTLPLMALLALSSIVAFVLPRKRKN
What is the function of this protein?
Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source.  Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization.  Promotes also resistance to hydrogen peroxide and killing by neutrophils.
What are the official names of this protein?
Iron-regulated surface determinant protein B, Fur-regulated protein B, Staphylococcal iron-regulated protein H, Staphylococcus aureus surface protein J.
What is the protein family that this protein belongs to?
Belongs to the IsdB family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A.
Protein: HIS4_SODGM
Sequence: MIIPALDLIDGAVVRLHQGDYQTQCHYGADPLPRLQDYLRQGAEVLHLVDLTGARDPQTRQIPLLRRLLAGVAPALVQVGGGIRSAADVEVLLEAGATRVVVGSTAVLQPQEVQRWFERFGPDALVLALDVRIDDDGQRRVAISGWQEDSGATLEQVITQYRPLGLKHVLCTDISRDGTLTGSNVSLYRSLCDAWSDIAFQSSGGIGSLADIAQLRHSGVQGVIVGRSLLENKFTVAEALACWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_STELO
Sequence: MTNIRKTHPLMKILNDAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTTTAFSSVAHICRDVNYGWFIRYLHANGASMFFICLYAHMGRGLYYGSYMFQETWNIGVLLLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAAVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGGLLLILTLLALTLFTPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILIFIPMLQTSKQRSMMFRPFSQLLFWVLIADLLTLTWIGGQPVEHPYIIVGQLASILYFLLILVLMPTAGLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PAND_DEIGD
Sequence: MERIMFRAKIHRATVTQADLDYVGSVTIDQDLLDAADILVNERVDIYNITNGNRLSTYALSGPRGSGVIGINGAAAHLVQPGDLVIIAAYGNFSEEEARTLEPRVVLVDAQNRILDLQPA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1516_ACTPJ
Sequence: MSIQSSEIIETIKMVADQNFDVRTITIGIDLHDCISADIDELNKNIYQKITTIGKDLVETAKILSAKYGIPIVNQRISVTPIAQIAAATKADSYVSIAQTLDRAAKAIGVSFIGGFSALVQKGMSPSDEVLIRSIPEAMKTTDIVCSSINIGSTRAGINMDAVKLAGETIKRTADITPEGFGCAKIVVFCNAVEDNPFMAGAFHGSGEADAIINVGVSGPGVLKEALENSNATTLTEVAEVVKKTAFKITRVGELIGQEAAKMLNIPFGILDLSLAPTPAVGDSVARILEAMGLSVCGTHGTTAALALLNDAVKKGGMMASSSVGGLSGAFIPVSEDEGMIAAAESGILTLDKLEAMTAVCSVGLDMIAVPGKTPAHTISGIIADEAAIGMINSKTTAVRIIPVTGKDVGESVEFGGLLGYAPIMPVKEGSCEVFVNRGGRIPAPVQSMKN
What are the official names of this protein?
UPF0210 protein APJL_1516.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: M1_I66A1
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: MDCC_PSEPU
Sequence: METLNFQFPAAEPGRGRTLVGCVSSGDLEVLIEPGTAGSLQIQVITSVNGSAARWAQLFQRLFEGRAWPAVNIDIHDFGATPGVVRLRLEQGFEEIAHD
What is the function of this protein?
Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.
What are the official names of this protein?
Malonate decarboxylase acyl carrier protein, Malonate decarboxylase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the MdcC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_YEAST
Sequence: MLRTRVTALLCRATVRSSTNYVSLARTRSFHSQSILLKTAATDITSTQYSRIFNPDLKNIDRPLDTFARRHLGPSPSDVKKMLKTMGYSDLNAFIEELVPPNILKRRPLKLEAPSKGFCEQEMLQHLEKIANKNHYKVKNFIGKGYYGTILPPVIQRNLLESPEWYTSYTPYQPEISQGRLEALLNFQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFNISRKKKLKYVIDKKLHQQTKSVLHTRAKPFNIEIIEVDCSDIKKAVDVLKNPDVSGCLVQYPATDGSILPPDSMKQLSDALHSHKSLLSVASDLMALTLLKPPAHYGADIVLGSSQRFGVPMGYGGPHAAFFAVIDKLNRKIPGRIVGISKDRLGKTALRLALQTREQHIKRDKATSNICTAQALLANVASSYCVYHGPKGLQNISRRIFSLTSILANAIENDSCPHELINKTWFDTLTIKLGNGISSEQLLDKALKEFNINLFAVDTTTISLALDETTTKADVENLLKVFDIENSSQFLSEDYSNSFPREFQRTDEILRNEVFHMHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNSTVEMMPITWPQFSNIHPFQPSNQVQGYKELITSLEKDLCSITGFDGISLQPNSGAQGEYTGLRVIRSYLESKGENHRNVCLIPVSAHGTNPASAAMAGLKVVPVNCLQDGSLDLVDLKNKAEQHSKELAAVMITYPSTYGLFEPGIQHAIDIVHSFGGQVYLDGANMNAQVGLTSPGDLGADVCHLNLHKTFSIPHGGGGPAGAPICVKSHLIPHLPKHDVVDMITGIGGSKSIDSVSSAPYGNALVLPISYAYIKMMGNEGLPFSSVIAMLNSNYMMTRLKDHYKILFVNEMSTLKHCAHEFIVDLREYKAKGVEAIDVAKRLQDYGFHAPTLAFPVPGTLMIEPTESENLEELDRFCDAMISIKEEINALVAGQPKGQILKNAPHSLEDLITSSNWDTRGYTREEAAYPLPFLRYNKFWPTVARLDDTYGDMNLICTCPSVEEIANETE
What is the function of this protein?
The glycine cleavage system (glycine decarboxylase complex) catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), mitochondrial, Glycine cleavage system P protein, Glycine decarboxylase, Glycine decarboxylase complex subunit P, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
What are the subcellular locations of this protein?
Mitochondrion.