PharMolix/UniProtQA huggingface dataset:
Protein: EAF1_KLULA
Sequence: MSSASKGNATGSKSPEQLLEERRHLLVQLYCISQITELKNVENHERIGKEIEKFLDQHTLIKDKPIDINALPKFRPRDVSSDRKLNNRSKSSSPSEVKRELKKQRSKDVSPSGSEEHDVDTQTLPQSQTRVVPRVQSQQSIQQSSRQSMVQAQSSRQLQQQQLQKQRSVSPTQKLPITHNNVPPVVVQAHMEPKSVQYPETQSKPSTSGKRLLDEEQQDISENQISKRQRLDSGNLSNSTAARNAATMEIPPHPYSQMIDISQLHADPTPIGVKEPQPYIIESIINNVSKEERKTFFEDDINVKEAVYMITKENAPTKLAKGMPIQEIKYLSQTLPLLRLIPQSQKALTTDLINTALNERRITVVASRIEELRRLNLWSLRQPRKFIDPVTASQPVTHHNVLIEEAKWMREDFRESLNYKIAMCTQMAQAVMEFWTYGKVCCINCKSIPPPSKDIEDIASSQDMGTKISTVEPEQKDKESNTSPDQSNDDGSSKIAEDVEMSEDGVKSSTGLTDGSEAVEEKSENGIKEGDKETDKNSSEEPTIDIQKLLKRVNPKDEIVAPSLPVTSMEVYLAKKSSSPFRNYIDIKELSTLGAAISNSLPLYGLLDEKNLDSSRPLPFEPVSKAISPLDEDHFMKLVEKQFVDEEPSLVPLSKRRGMFYGNRRSHYLRPPNAPSLRYLKFRTPTIWLPEDDQELVKNINQYAYNWDLISSQMSNHHKREYVSNIERRTPWQCFERFVQLNEKFNIADMKGPKAHNAQIWLYEAHKLQQQQKRRISPLGVGSESIQRGHRRLRWASMFEAMRKCIKKRENAPRPNPSQPRKPFDVKNMSVPTPQEMSDLKAQRDEALRRDMQIKRAAKQRMQMAQLQQGKLPLTTASSPNLPMANNPNSKDSRIRSKQSTPQSAPPLGEKEKVTTQTPTQRNTKPANKREIIEGYAKKILFQKPNFTPELALMAAENIYRSLPLSDQQRKTVIYDNVAQPKVRPPEMKHSSPTPQEILQRAQKK
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF1, ESA1-associated factor 1, Vacuolar import and degradation protein 21.
What is the protein family that this protein belongs to?
Belongs to the EAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRH_PSYA2
Sequence: MSDKTPRYSRILLKLSGEALAGTKDMGIDTEVLDKMSLSIAHLRGLGVQVGIVVGGGNLYRGAQLQKEGLVGRVTGDQMGMLATVMNGLAMRDALERRNIKTRLMSALPIGEVTESYSSRNAIRYLKNGEVCIFVAGTGNPFFTTDTAACLRGIEIEAGLILKATKVDGVYDKDPSLHSDAVKYDGLTFDEVLEQKLGVMDLTAIALCREHDVPLQVFDMNKPNALLNVVMGENEGTRVYH
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_METEA
Sequence: MVEPMNWISEVVRPRIKTLFKRETPENLWVKCPDTGQMVFHKEVEQNHWVIPGSEHHLKMSATARLKMMFDEGTWIDVPLPEVPADPLKFRDEKRYVDRLKEARAKTGMPDAFKIGFGRVGSLPMTIAAQEFGFMAGSLGMAGGEAFVRGAETALEKRTPYVLFAASGGARMQEGILSLMQMPRTTVAVRRLRAARLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGALICFAGPRVIEQTIREKLPDGFQRAEYLREHGMVDQVVHRHQLKETISRLCGLLMDVRRTPEPGTAPEPTTPEPLPNAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBAY_ECOBW
Sequence: MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires KbaZ subunit for full activity and stability.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Ketose 1,6-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily.
Protein: PLSB_COLP3
Sequence: MLALRSFFYLLLKFPLKLLVRCKIITDSQNITDQPNQPIFYIVRHQSASDLLALQSACKKQNLPDPLGKVTINGESFNRTLCLAKSTPLCSWRKSSKTTATAQGLALLNQHVIDENIDAKLIPANLIWGRTPTKERKNLNIGTLLADQESPNWLRKFFIVLFLGRDTLVRFSEAFSLRNISDNHGSDEAAAHKFLRVARFHFHRQTIAAKGPRLMHRKQMFTALFANPSVKRIISDEAKNKKVSEAEIKKKALVMMNEIAGDYSVSWLRFGEIILHWLWKRLYSAIKVSNAKVLRKLAQDGHEIIYVPCHRSHMDYLLLSYVILQEGLVMPRIAAGINLNFWPAGTIFRKGGAFFIRRSFGGNRLYSTIFREYLGLLFERGYGVKYYTEGGRSRTGRVLAPKTGMLAMTIQSLLRGIDRPLTLVPVYLGYEHVMEVGTYHKELSGSEKKGESMFGVLKAIKSLRNYGNGYVNFGEPMNINEFLNKQVPDWKDSIDPIDPQKPSWLTPTVNVLADQVMENINKSAALNGVALIALILHASKNKALSKLELETQLDFFLNIQRQAPFSEQLTIPEETGAELLTHVISLNKVTITEDSFGSLVSLSETANTEMRYYRNNILHTYVVPALVCRLLDKHSKINQDELVIKVQNVTALLKEDLYLYQDSTHVEQQTLRVLTVLKEMEIAKQTKAGFWSLSDDVGLLSQVHAMAECIDESLQRLAIITSLTSRLAPLSKRDLETKVVAIAKRLSVLNNINAPEFIDKRAQSTLIATIREQGYIDLDDDGLLIASSTMAEIKATVINLVDIEVLQSIAR
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PYRF_SYNE7
Sequence: MTDLAARDRIIVPLDVPDVEAAITLIDRLPEAQFFKVGLELFVATGSTVLTILKERQKKIFLDLKLHDIPNTMAGACRSAARYGVDLLTIHATAGKPALEAAQAGAIAGAAAAGVQPPTLLAVTVLTSLSQQQLTEELHVPEAVPNYVQHLARQAEACGIGGCVCSPQELVVLKTACSDDFVRVTPGVRPTWAAAGDQQRVMTPQQAIAAGATYLVVGRPITAADDPAAAFQRVCEELTP
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: OPDN_PENO1
Sequence: MSDELKDNAAKEASFGAFLTRQLMKSVPAVTGNLDGKVAIVTGANVGLGLACARQLLSLQLSHLILAVRSLRKGEAAALELQASFPHARVEVWALEMESYASIQAFVSRCHSELGRVDIAILNAGLALKRFQTCTNPQTTPREITLQVNFLSTVFLALLLLPILGAKKEKKDAVFIPGRLTLVGSDTVYWVNARELKSRPLLQAANSSEGFDGFEQYKMSKLFVLMFVAKLARDLVSPDQVIVNVACPGLCKGTAFVREPDSNWAKQAIVSSLIRLVGRTPEQGARVYLAAAILQGPKSHGSMISEGDILP
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of oxopyrrolidines, polyketide-amino acid hybrid compounds with feature structures of tetramic acid (PubMed:36005526).  Does not seem to play a role in oxopyrrolidines A and B biosynthesis (PubMed:36005526).  May be involved in further modifications of these oxopyrrolidines (Probable).
What are the official names of this protein?
Short chain dehydrogenase opdN, Oxopyrrolidines biosynthesis cluster protein N.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: Y2119_SYNJB
Sequence: MDPLPRRASLQNTGNVGEGWVRQYLCQQGWQILAQRWRCPWGELDLVAHKADVLIFVEVKTRSPGSWDRGGLLAVGIPKQRRLIRAAQAFLSQHPHLSELSCRFDVALIERRASREGVSYALVDYLPAAFEIC
What are the official names of this protein?
UPF0102 protein CYB_2119.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: VIRB2_RHIRD
Sequence: MRCFERYRLHLNRLSLSNAMMRVISSCAPSLGGAMAWSISSCGPAAAQSAGGGTDPATMVNNICTFILGPFGQSLAVLGIVAIGISWMFGRRSLGLVAGVVGGIVIMFGASFLGQTLTGGS
What is the function of this protein?
VirB proteins are suggested to act at the bacterial surface and there play an important role in directing T-DNA transfer to plant cells.
What are the official names of this protein?
Protein virB2.
What is the protein family that this protein belongs to?
Belongs to the virB2 family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: ASR_ECOL6
Sequence: MKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNAKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA
What is the function of this protein?
Required for growth and/or survival at acidic conditions.
What are the official names of this protein?
Acid shock protein.
What is the protein family that this protein belongs to?
Belongs to the Asr family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CYAY_VIBVU
Sequence: MNNTEFHQLVDNELQLIEEAIDESGADIDYETTGNVMTLEFDDRSQIIINRQEPMQEIWLASKSGGFHFQYKAGQWICSKTGVEFAHMVKQECEKHAGESIDWA
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: SYK_THEAB
Sequence: MLKEFREQRINEIKQISAKGVNPYPYKFEKTHSSQDIKAQFENLNPGEVKEDASVSTAGRIMSLRHHGKSAFFHIKDFFGRIQAYIRQDIVGKDVYEFFKEHIAIGDIVGVKGSVFKSKTGEVTILVKEIELLNKPLRPMPEKWHGIKDKEVLYRQRYVDMIANDETLNRFRIRFEIIKLIREFLNSKGFIEVETPILEYVTGGASARPFITHLNVFDIDMYMRIATELYLKRFIVGGFEKVYELGKNFRNEGLSYKHHPEFTSIEIYQAYADYEDMMNLTEELFVFIVEKLFGTTKVKYQDIEIDFSRPWRRVKMRDFIKEHLGVDILEDTEEKMLEVLKQHDVEVEIKDKGHLIEKLWDLVEDKVVQPTFLLEHPVEISPLAKKHREDPRVTERFELIIYGREMANAFSELNDPVDQYERFLRQAKLREAGDEEAQMMDKDFVRALEYGMPPTGGLGIGIDRLVMLLTNSPTIRDVIAFPLVRPISFEEEEMNLEGGSQE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFRD1_HUMAN
Sequence: MPKNKKRNTPHRGSSAGGGGSGAAAATAATAGGQHRNVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGIKNALASKMLYEFILERRMTLTDSIERCLKKGKSDEQRAAAALASVLCIQLGPGIESEEILKTLGPILKKIICDGSASMQARQTCATCFGVCCFIATDDITELYSTLECLENIFTKSYLKEKDTTVICSTPNTVLHISSLLAWTLLLTICPINEVKKKLEMHFHKLPSLLSCDDVNMRIAAGESLALLFELARGIESDFFYEDMESLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETIKFGPERMYIDCWVKKHTYDTFKEVLGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKCRDKRADVGEFF
What is the function of this protein?
Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF.  May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity).
What are the official names of this protein?
Interferon-related developmental regulator 1, Nerve growth factor-inducible protein PC4.
What is the protein family that this protein belongs to?
Belongs to the IFRD family.
Protein: TPM3_RAT
Sequence: MAGSTTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
What are the official names of this protein?
Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3, Tropomyosin-5.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y1570_HAEIN
Sequence: MEVERPADKQGNREKTVGFKLPDGTIRVTDKGFDYNVGRLNYKPNLDLYPEKLAHAFAKVEMKGGEFKHDFELLAKHMAEMKQTLSPEGKKLTAEQMLQVRDSLTKNFKFAAGVLSAESKDLLKSKTGTVWLSDDTLIKQFNSRDGQDFGIDEYERCQISSMLPSIYYK
What are the official names of this protein?
Uncharacterized protein HI_1570.
Protein: ARAA_ECO57
Sequence: MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVKALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: OTAY_ASPC5
Sequence: MTTPTPTTLKHHATTILTTLVNDRQTAAIEHLLHPTITLKHNDLPAMSKSELIAFWPEVLAQSPHFRVQIRDVIAEGNKVWVYSRVEGRLGEGVMDDFHMMVFDEEGLVVRSTGVQRVVEGEM
What is the function of this protein?
Probable cyclase; part of the gene cluster that mediates the biosynthesis of ochratoxin A (OTA), a mycotoxin composed of a chlorinated type I polyketide dihydroisocoumarin moiety linked to L-phenylalanine, and demonstrated to have nephrotoxic, immunotoxic, genotoxic, neurotoxic, and teratogenic properties (PubMed:33391201).  OtaY is probably involved in the polyketide cyclization (PubMed:33391201) (Probable).  The pathway begins with the highly reducing polyketide synthase otaA that catalyzes the formation of the isocoumarin group during the initial stages of biosynthesis, starting from one acetate and 4 malonate units, to originate the characteristic pentaketide skeleton 7-methylmellein (7-MM) of the OTA molecule.  The newly identified cyclase otaY might be involved in the polyketide cyclization reaction during the initial steps of the OTA biosynthesis.  7-MM is then oxidized into 7-carboxymellein (also called ochratoxin beta) by the cytochrome P450 monooxygenase otaC.  The NRPS encoded by the otaB gene is involved in the linking of phenylalanine to the dihydroisocoumarin ring.  The reaction catalyzed by NRPS results in the production of ochratoxin B (OTB), which is the non-chlorinated analog of OTA and which subsequently serves as the substrate of the halogenase otaD for chlorination activity to form the final molecular structure of OTA, containing a chlorine atom in the C-5 position of the molecule (PubMed:33391201) (Probable).
What are the official names of this protein?
Probable cyclase otaY, Ochratoxin A biosynthesis cluster protein Y.
What is the protein family that this protein belongs to?
Belongs to the aurE cyclase family.
Protein: NUDK_YERPP
Sequence: MSVKIENIQCELLSKNWFKLHKYTFDLKTDEGTSVQQIREVYDRGNGATILLYNRQQGTVVLIEQFRMPTYVNGNASGMLLEACAGLLDNDSPEACIRREAMEETGYQVDKVQKLFEAYMSPGGVTELVYFFAAEYHPDQKITDEVGVEDEVIEVVELPFHDALAMVADGRIKDGKTIMLLQYAQIHFFPSSLTPQRC
What is the function of this protein?
Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.
What are the official names of this protein?
GDP-mannose pyrophosphatase, GDP-mannose hydrolase, GDPMK.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudK subfamily.
Protein: YOD2_CAEEL
Sequence: MGKHTKFGSSDDEGETETSVAKRQKDEKKEKKKEKRDRSRSPHKERERSPKRDRHPEKNESRRHDDRDQERRRDYGRNDRRDDRRGDGSWKTDRNDRNDRRNDFQRRDDKNRLSAEEIAAQRKALWGNKKVAGESSSSNTTDTASSSSEPATGGKNEKLWSSAIAATGVDSSKANKFMRLMGVKNAPKPTDDSSRLSDEKNRQDKMLNDLEKQYAIARETTHMGRGTGFGFGH
What are the official names of this protein?
Uncharacterized protein ZC262.2.
Protein: ATPH_EUCGG
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PEX6_COLOR
Sequence: MTTSELVPPPPARRSPRTRRRRQDKPALSARLVLDDHEINGDVGVLSEDLFTDLFPHLRNVPSREDGSEDIHHVAIAPWEPSPSPTETAWTVVPVLKSSALKPSTVQFSPSSLSLQSFATILQQVAPSKLSSHSRSGIEVQILDVVALSLDTVFVSLESELTKRLEQGEGTFFRDRPNKGKGKAPAQPDTPEDRLISALRVALGSLKVLHSGDLFSLPLPPHPVTHVPPNPGKIMLCEPVSQGILSDDTKIVLMRGRVHAKRGQSAPAIPPNRSLNGVPEDDEDDTANDQFYSAAEDRYKTDAATTEMDTVTETEESDLSGVDHDDDLSDDFMDDMISLQAPTLPTTASGVSTMQPGTPMTIGRGRKTNGIATPASVFSNFTATTARPDRPRGRLFKAQGLIRPILIDLLHPKPAPEDDEEARIFVDIASLSKIGCFSGDWVRVEAAEEPPANGFGAFGLGSFTSLEPTESNWRPVRVYGLPEGYSQRPVTRIPSAKHGERRMSFFESQLQKPTSPTAYISPVLLANLESPSYLRLSPIKRGTYQGKGTLPKFTSASRPPYARDITIQHVRSPVTAERAYQSAVLGGLKRYFAQKIRLVRTGDLIAVPIDTQLGKALQEQPSANGSEVDDVMALAKDESCRFDQVAWFKVGHIQTQKTDADHDQTEDLWGGVACIDSSSVAMHGSGFATSRTPATKASTWPYYLGVKKMPMKSNGASALMVPEQDQRFVSPLRRRLRELLAAATSPRAIHLKMPPVAILLTSTHRNIGKATLASEACSDIGLHTYAIDAYDILSEAGTSGGDVKTEGLLRTRSERAMSCGPDTTALLIKHVEALTADRMVSTMKEILQDTRVLVATTSDVDKVPDGVRGLFSHELEVGAPDEAEREGILRTIVEDRGINLDPEVDLNGIALKTAALVAGDLVDVVDRALVAQRLRLEQISSKTGQAVTVRDLQVAGGAMARCVTKGDFDVAVEAARKNFAGAIGAPKIPNVTWDDVGGLNNVKDAVTETIQLPLERPELFAKGMKKRSGILFYGPPGTGKTLLAKAIATEYSLNFFSVKGPELLNMYIGESEANVRRVFQRARDARPCVVFFDELDSVAPKRGNQGDSGGVMDRIVSQLLAELDGMSGGDDTSGGVFVIGATNRPDLLDPALLRPGRFDKMLYLGVSDTHDKQLKILEALTRKFTLHPSVSLHSVAQQLPFTYTGADFYALCSDAMLKAVTRQAASVDAKIRELEAQPRSRTGPISTAYFFDHHATPEDIAVMVTEEDFLAANRELVPSVSAGELSHYEQVRAMFEGPPEKDRQQQQQQQQRPSGLRAVSGSSVVSKGKGKAIAGGSGKGKGKAVATGSDDEYGSEGEVAVVNGKGKGKGKAVAGFQDGTASDDEGLY
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling (PubMed:11487704).  Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel (By similarity).  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5 (By similarity).
What are the official names of this protein?
Peroxisomal ATPase PEX6, ClaPEX6, Peroxin-6, Peroxisomal biogenesis factor 6.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: BORC5_MOUSE
Sequence: MGSEQSAEAESRPGDLNASVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNAKLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFCFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPEAERLEPFSMKPERERH
What is the function of this protein?
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.  Thereby, it may indirectly play a role in cell spreading and motility.
What are the official names of this protein?
BLOC-1-related complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the BORCS5 family.
What are the subcellular locations of this protein?
Lysosome membrane; Lipid-anchor; Cytoplasmic side.
Protein: RSMH_UREPA
Sequence: MEFNQHITVLLNETIELLNIKPDGIYVDCTFGRGGHSQLILKKLSKKGKLICLDQDQEAINFANNLFKNNTNVIVIKTNFKNLKSALSAHKIFYVDGFIFDLGLSSPQLDDPKRGFSYHKNAWLDMRMDQSQNLNAHYIVNNYSFAKLVSIFKRYGEIKYPKIIADAIVKERSIKEINTTLELVEIIKKYSPKKNLFEKKHPARLFFQAIRIEVNDELNILEKAFNDAISMLNPLGVVAIISFHSLEDKIVKKVFNNYAKIKLPKEVPINNYVNKYSLLNQKIMPSTQELNDNNRSRSSILRGLIRNY
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_BORPA
Sequence: MSETQNTQVAKRQRTLVGKVVSNKMDKTVVVLVERRVKHPIFGKIIMRSAKYKAHDESNQYNEGDTVEIAEGRPISRSKAWRVVRLVEAARVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SALM_DROME
Sequence: MKNHLSNVLCAMRSDFKDNHQETINKMIQFGTVKYGIVKQLKDRARSADKDIGSDQEENGGCSPLTTATTTASPSRSPEPEEEQPEEQSTSEQSIPEQSTPDHQLENDIKSEAKSEIEPVEDNNNRVAMTKPSSEEREPNASGSMPSSPVAEASAEEAATERTPEKEKEKDVEVDVEKPDEAPSSAVPSTEVTLPGGAGAPVTLEAIQNMQMAIAQFAAKTIANGSNGADNEAAMKQLAFLQQTLFNLQQQQLFQIQLIQQLQSQLALNQAKQEEDTEEDADQEQDQEQETDTYEEEERIADMELRQKAEARMAEAKARQHLINAGVPLRESSGSPAESLKRRREHDHESQPNRRPSLDNTHKADTAQDALAKLKEMENTPLPFGSDLASSIITNHDDLPEPNSLDLLQKRAQEVLDSASQGILANSMADDFAFGEKSGEGKGRNEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVHFQRHAQKFPHVPMNATPIPEHMDKFHPPLLDQMSPTDSSPNHSPAPPPLGSAPASFPPAFPGLQNLYRPPMEILKSLGAAAPHQYFPQELPTDLRKPSPQLDEDEPQVKNEPVEEKDQREEHEQEMAECSEPEPEPLPLEVRIKEERVEEQEQVKQEDHRIEPRRTPSPSSEHRSPHHHRHSHMGYPPVVQPIQPAALMHPQSSPGSQSHLDHLPTPGQLPPREDFFAERFPLNFTTAKMLSPEHHSPVRSPAGGALPPGVPPPPHHHPHHMARSPFFNPIKHEMAALLPRPHSNDNSWENFIEVSNTCETMKLKELMKNKKISDPNQCVVCDRVLSCKSALQMHYRTHTGERPFKCRICGRAFTTKGNLKTHMAVHKIRPPMRNFHQCPVCHKKYSNALVLQQHIRLHTGEPTDLTPEQIQAAEIRDPPPSMMPGHFMNPFAAAAFHFGALPGGPGGPPGPNHGAHNGALGSESSQGDMDDNMDCGEDYDDDVSSEHLSNSNLEQEGDRSRSGDDFKSLLFEQKLRIDATGVVNTNPVRPRSSASSHGHSVGSTSAPTSPSVHASSQVIKRSSSPARSEASQGALDLTPRAAPTSSSSSRSPLPKEKPVSPPSLPRSPSGSSHASANILTSPLPPTVGIDCLPPGLQHHLQQQHQHLMQQQAAVAAAAAAQHHHHQQMAALHQHQEQLRREAAEAQQKAAAAAAAAAAAAAAQRQTPPQARDQRQEGGPGAGPPPNPLMGARPPFGMFPNLPLFPPATTQNMCNAMNQIAQSVMPAAPFNPLALSGVRGSTTCGICYKTFPCHSALEIHYRSHTKERPFKCSICDRGFTTKGNLKQHMLTHKIRDMEQETFRNRAVKYMSEWNEDRE
What is the function of this protein?
Required for the establishment of the posterior-most head and the anterior-most tail segments of the embryo.  Probably function as a transcriptional regulator.  Could repress the transcription of the tsh gene.
What are the official names of this protein?
Homeotic protein spalt-major.
What is the protein family that this protein belongs to?
Belongs to the sal C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_GALLA
Sequence: MAPNIRKSHPLLKMINNSLIDLPAPSNISAWWNFGSLLAVCLMTQILTGLLLAMHYTADTSLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIFLHIGRGLYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWTWGGFSVDNPTLTRFFALHFLLPFAIAGITVVHLTFLHESGSNNPLGISSNSDKIPFHPYYSLKDILGLTLMLTPFLTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLIPFLHKSKQRTMTFRPLSQTLFWLLVANLLILTWIGSQPVEHPFMIIGQMASLSYFTILLILFPTIGTLENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.