PharMolix/UniProtQA huggingface dataset:
Protein: RF2_HELAH
Sequence: MDNYTYSELLKSLQNKCDNIALIIKPEKVKQKLERIEKEQEDPNFWQDVLKARDTNKEKVRLNRLLETYQKTKNALDESVELFEIAQNDNDEVTLSLLYEEAPILEHGVQKVEIEIMLSGEHDASNAIITIQPGAGGTESQDWASILYRMYLRWAERRGFKSEILDYQDGEEAGIKGVAFIIKGENAYGYLKNESGVHRLVRISPFDANAKRHTSFASVQISPELDDDIDIEIDEKDVRYDYYRASGAGGQHVNKTESAVRITHFPTGIVVQCQNDRSQHKNKASALKMLKSKLYELELEKQQSTAKNEEKSEIGWGHQIRSYVLAPYQQVKDARSNIAYSNVEAILDGDIDAILEGVLIAKA
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_YERPP
Sequence: MNDIENLDRPPAIFIMGPTASGKTALSIALRQRLPVELVSVDSALIYRGMDIGTAKPSAQELALAPHRLIDIRDPAESYSAADFRKDALKEMADITAAGRIPLLVGGTMLYFKALLDGLSPLPSADPQVRQRIEQQASELGWGALHQQLAVIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTKISGETLPYRVHQFAIAPASRELLHQRIELRFHQMLDAGFEAEARVLFDRGDLHTDLPAIRCVGYRQMWSYLSGEIDYNDMVYRGVCATRQLAKRQMTWLRGWSSVQWLDSDKPGEALDSVIQVVSA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: AROC_FRATO
Sequence: MSGNTFGKIFTVTTCGESHGDSLAAIIDGCPSNIPLCEAYIQLELDRRKPGQSKFTTQRKEPDEVKIISGVFEGKTTGTPIGLIIKNQDQKSKDYSEIKDKFRPGHADYTYFKKYGIRDYRGGGRSSARETAMRVAAGAIAKKILKHYGIEIYGFCSQIGSLKIDFIDKDFINQNPFFIANKNAVPACEDLIHSIRKQGDSIGAEVTVVATGLEAGLGRPVFDRLDASIAYAMMSINAVKAVSIGDGFDCVAQKGSQHRDEITQQQGFLSNHAGGILGGISTGQDIIAKLAFKPTSSILQPGKSIDVQGNDTTVITKGRHDPCVGIRGVPIAEAMLALVLVDELLITRSYRD
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CIAO1_CRYNJ
Sequence: MLRLQSLGSLPAHAEPAWTVSFNPTRSLLASCSTDRTIRLYSYIIPSSSDGLPSQDDSQAVFSLAKVIETDHKRTVRSIAWSPDGRTLASGSFDSTVGVWEEVIPLSDDEEEEDEGAQGVYKPAGVDSDGDGDGGKEKEWECVTTLEGHESECKSVGFSSDGALLASCSRDKSVWVWEVQPDADFECIAVMMEHSQDVKSIAWHPHEEILASASYDSYIHLAYDDPDSDWCIFQKLHPSLPSTPLTIPSTSPSHLIDALVPTEEEKKAEAELQVPPLEEDETVWCLAWSPDGRWLASGGDNGGIRLWQRTGSQPDSAFKEILHTAAHSRSVFSLSWSPPYPSAESAGSTDSTDLGMLASAGEDGKIIIWQITVPPSPSSASQEIDNEQISIRPIAAQKDAHGVNDINSVAWCVREDKKGWGMLSSAGDDGSVKVWRVVRD
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
Protein: CARP_RHIPU
Sequence: MLFSKISSAILLTAASFALTSARPVSKQSDADDKLLALPLTSVNRKYSQTKHGQQAAEKLGGIKAFAEGDGSVDTPGLYDFDLEEYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGCDNSEGCVGKRFFDPSSSSTFKETDYNLNITYGTGGANGIYFRDSITVGGATVKQQTLAYVDNVSGPTAEQSPDSELFLDGMFGAAYPDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMNTNDGGGQVVFGGANNTLLGGDIQYTDVLKSRGGYFFWDAPVTGVKIDGADAVSFDGAQAFTIDTGTNFFIAPSSFAEKVVKAALPDATESQQGYTVPCSKYQDSKTTFSLVLQKSGSSSDTIDVSVPISKMLLPVDKSGETCMFIVLPDGGNQFIVGNLFLRFFVNVYDFGKNRIGFAPLASGYENN
What is the function of this protein?
This enzyme, capable of clotting milk is frequently used for cheese production.
What are the official names of this protein?
Mucorpepsin, Mucor rennin.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: DLT1_KLULA
Sequence: MVTSWYKIWYHTTQVIFILLFVGFSVVVPLDCIVQASDSSNDAVNTFIVVGAAVVLVVFGISISFARVLIFRRSLQDIPKKYIPVTAQDMRHKPSREYVIENMKRAGELAEKFKVPKEPVLHAGMEPKDSDMFPEHLKYAEIVKFISDRFRFDGALLLNFVTESDLSTTFKTALHKLFENEKHPYKQYLDEFISLYEKFRFSGQDIERNDFVKFLRLYKYLADLSNNLDLTRIESVPSQFLHVPTEDYDTDARSRTDSEFSTPYLRPYPSDAFMHNTTPASHVGSRSSNFSYDIDESAEPPESVEDQQRYHDMLTRVDTYNTVIHR
What is the function of this protein?
Required for growth under high-pressure and low-temperature conditions.
What are the official names of this protein?
Defect at low temperature protein 1.
What is the protein family that this protein belongs to?
Belongs to the DLT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRMB_CHLT3
Sequence: MGKGRGRHPSRLKVKPPEPEILAKYLHHWNTKELYHHPDTFLQVSSPSFFQNENPLEIDIGCATGDLVCSLAQKNPQVNFIGVEVSMKPLYRAIKYSVREQIENVRFIKTDFRLLYPLLPDASVQKIFFHFPVPVVRAKDSKYLIFSEDFLSEMHRALQVGGMISVISDSAEYFPIMRELGQNDTRYELISDEAKCMALEPDEKSYYHKYWDAQGREKFRFILVKK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: VOME_RAT
Sequence: MWVLQALAIMLSIQAGVLDLVEVPPVVRSLPVALPAPVNLPAVLPGSPGLNDPAKNRMLPPKRPGAPSRGGKCAPAARYFLSSDKLQAYLLSILPPQIEDMVKCDKVNMEGVLGDILATMQDSNLLSILDITSLLQGGGGLGLGGLLGKEGNEDPSKPSSGSKATGGLGQLLPEGLPGKEGLGGLLNLGGGKGSGKGLLNGDGLSNVVKPLDDIVENVDSLKAAVQDKVKSVVPENIKDPFSDLLNMDIQETMLKLKVKQVKVGSTDINMGADGIKVLSEVTADVEGEGLLGPVFTLLQFQSVMDVTMNIAVSSNNTQCVNLDVQDTHMHVKEMNIQLLQTVTETVPLPTSLPLNDIIPIVLTAKMNENLEKSDSCGIVLSDFNDCKNTTGLFGYQVHTARISPKGLSIDYCVKANIDNKTVPVPGGRLPPDPKNANVSITTASSALRTLVKYVAKQSSVQMNDLEAQITYIAFAPQENNMLRLLYKVDITKDSQPYATGETKLFISHASKILNSKLVPDVKLTRSEHSVVPPETKEEVEGIMAEVTRKAWSRFNELYKKMSIPDGVSSNTLTNSDVKLLRSNDLQAAS
What are the official names of this protein?
Vomeromodulin, BPI fold-containing family B member 9.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMM_PSEMY
Sequence: MSTTPAVAEDLIVLGKIVSVHGVRGEVKVYSFTDPIDNVLDYRHWTLRRDGEVKKVELASGRLQGKVLVAKLKGLDDREIARTYAGFEICVPRSELPDLEEGEFYWYQLQGLKVIDQAGQLLGVVDHLFETGANDVMVVKACAGSLDDRERLLPYTDQCVLSIDLAAGEMRVDWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFH1_AZOVI
Sequence: MAMRQCAIYGKGGIGKSTTTQNLVAALAEMGKKVMIVGCDPKADSTRLILHSKAQNTIMEMAAEAGTVEDLELEDVLKAGYGGVKCVESGGPEPGVGCAGRGVITAINFLEEEGAYEDDLDFVFYDVLGDVVCGGFAMPIRENKAQEIYIVCSGEMMAMYAANNISKGIVKYANSGSVRLGGLICNSRNTDREDELIIALANKLGTQMIHFVPRDNVVQRAEIRRMTVIEYDPKAKQADEYRALARKVVDNKLLVIPNPITMDELEELLMEFGIMEVEDESIVGKTAEEV
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.
What are the official names of this protein?
Nitrogenase iron protein 1, Nitrogenase Fe protein 1, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: ABDH_PECCP
Sequence: MHDKLLIEGKLVAGKGEALAVFNPATGEQIAAIAQADLHQVDAAVLAAESAFAHWGQTTPKTRATLLLQIADAIEENAEAFARLESLNCGKPYHAALNDEVPAVADVFRFFAGAARCLSGSAAGEYLEGHTSMIRRDPVGVVASIAPWNYPLMMASWKLAPALAAGNCVVLKPAEQTPLTTFYLAHLLAEILPAGVVNIVFGRGADIGDALTGHEKVNMVSLTGSIATGAHILSHTASSVKRTHMELGGKAPVIVFDDADIDQVVDGIRSFGFYNAGQDCTAACRLYVQRAVYDKVVEALGNAVATLKMGDPHDETTELGPLITEQQLERVVGFVERAKALPHITVVTGGERVKGQGFYFQPTVLAGAKQEDEIVQKEVFGPVISITPFDDEAQVIGWANASHYGLASSVWTRDIGRAHRLAACLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSMYGLEDYTIVRHIMIRH
What is the function of this protein?
Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA).  This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal.  Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Gamma-aminobutyraldehyde dehydrogenase, ABALDH, 1-pyrroline dehydrogenase, 4-aminobutanal dehydrogenase, 5-aminopentanal dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
Protein: PYRD_IDILO
Sequence: MYNLIKPLLFRQDPEKTHELMLGILSKWHRTPLSLFWKQNVASKPVRVMGIDFPNPVGLAAGLDKNAECIDAFSQMGFGFIEVGTVTPVAQPGNDKPRLFRLTEDEAIINRMGFNNDGVDELVKNVKASSYKGVLGINIGKNKNTPEEQAIDDYLACLNKVYPYADYVTINISSPNTPGLRNLQHGSSLDGLLSSLKTAQLTLAKEYERYVPLVVKIAPDLEDHEVEVMAQSLLKNEMDGVIATNTTLSRDGLQSSQAGEAGGLSGKPLQDKSTRVIELLCKTLQRKIPVIGVGGIDSVESAEAKLKAGASLVQVYTGFIYQGPGLIRSIVSHL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SERC_SHESH
Sequence: MSTTYNFCAGPAMLPQAVMKKAQSELLDWNGLGTSVMEISHRSKEFIALTDKAETDLRELMSIPENYHVLFMHGGGRGQFSAVVNNFLGENGKALYLVSGSWSKSAVDEARKLTSDAQIDTLDLVVNDNGIGAVSIPELTGEAADYRYLHYCPNETVDGIEIFEDINSPWPIVADMSSNIMSREIDVSKFGLIYAGAQKNIGPSGLSIVIVRDDMLELPSLPQSSIMDYRLAVKHGSMYNTPPTFAWYLAAEVFKWLKSSGGVATMAEVNAKKAQLLYDFIDGSNFYNNTVSAQNRSLMNVIFYLANEDNNADFLAEASRAGLVALKGHRSVGGMRASIYNAMPIEGVEKLVEFMKGFAEKNNG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRO1_CAEBR
Sequence: MAYLGVDTSRIAGTQPLEMLLISSSSPDPHSTIIIDPRTGVSSWSYKGGELQGASTGLVEPLGKDGEHIVVTTKDRPLVHVIAVHSKDRFHQKCVLPGPVSAICSDRSGRFAFMSIKRQLYCWLLSTGELLSVIDAHYQNITKLALSDDDSMVFTASKDGAIHGYLVTELVSADRDSTVAPFRKWASHTLAVSDLKITHGSNPRILTTGADHIACLHSISMDSVILKASADRPLTSCAIDSAETRIFIGTEVGNIAQINLFQLGAEERDLLIQAGDEHNTKFRVLNGHSDEITRLTINTDGTLLASGDASGKYCIWEISSHQCLKVSTMRSTISTLRFIPFWPTISGGEHTKKFRPVWDLRREPTKCERLAIEVSNEFNADQKHWNDVIEDSIDQMLLESGSTTSAQLQWQVEAPMRKQAEVEKAEAEAMAQVITLGDDEDDAPEVGNQRRQNKKNNKKNRKLQKKLEAEQALKNKVIEEEAELIVIDDGEESNKKILDLQASMTELREENEKLKEINRQMYEFVAAEIVDR
What is the function of this protein?
Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity).  Required for processing ITS2 sequences from rRNA intermediates during 26S rRNA maturation (By similarity).  Required in the soma to promote normal proliferation and prevent germline tumor formation (By similarity).
What are the official names of this protein?
Pre-rRNA-processing protein pro-1, Proximal proliferation in germline protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat IPI3/WDR18 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: ISPDF_HELPG
Sequence: MSLIRVNGEAFKLSLESLEEDPFETKETLETLVKQTSVVLLAAGESRRFSQTIKKQWLRSNHTPLWLSVYESFKKALDFKEILLVVSELDYIYIKRHYPEIKLVKGGASRQESVRNALKIIDSAYTLTSDAARGLANIEALKSLFLTLQQTNHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKTLQSALNQGDFKDESSAILQAFPNRVSYIEGSKNLHKLTTSDDLKHFAFFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAVLGAIKGGDIGEWFPDNDPKYKNASSKELLKVVLDFSQSIGFELLEMGATIFSEIPKITPYKPAILESLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYKQKL
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: YM58_YEAST
Sequence: MLSSSSNRPISAHLTIHYKAIQEEEGEDMRSGAGSGGHHDDYFLESNRSPTPNKKHEFIKTVLNINDNDSEFSESCSPREKLHNEGACNTDLFGDFMSKRQQRLSNSMNIYDLYQCVHNLSPSNNNHQFIARRFSDSHIPSLHHRQQQQKVTTKNFVQPTKDIQRIASYAADSDQRVKYLPNYHQSAPSTALSAAESKAAVPRKLPDRDSTQNYVLKLQLSSPNSQPMSPRTRPGYRPSCSSSNCSSSSSSSACSSVSISDPNNITAYETNNVNPQFPSNQPLDISSPCARHHHRRNSIAVKFDKALYKKTTG
What are the official names of this protein?
Uncharacterized protein YMR206W.
Protein: HCAR_ECOLI
Sequence: MELRHLRYFVAVAQALNFTRAAEKLHTSQPSLSSQIRDLENCVGVPLLVRDKRKVALTAAGECFLQDALAILEQAENAKLRARKIVQEDRQLTIGFVPSAEVNLLPKVLPMFRLRQPDTLIELVSLITTQQEEKIRRGELDVGLMRHPVYSPEIDYLELFDEPLVVVLPVDHPLAHEKEITAAQLDGVNFVSTDPVYSGSLAPIVKAWFAQENSQPNIVQVATNILVTMNLVGMGLGVTLIPGYMNNFNTGQVVFRPIAGNVPSIALLMAWKKGEMKPALRDFIAIVQERLASVTA
What is the function of this protein?
Transcriptional activator of the hca operon for 3-phenylpropionic acid catabolism.
What are the official names of this protein?
Hca operon transcriptional activator HcaR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: ATPA_HALH5
Sequence: MSIKPEEISSLIKQQIENFQSDVQVQDVGTVIRVGDGIALAHGLESVMAGELLEFSNGVMGMAQNLEENNVGIIILGPYSEIREGDEVKRTGRIMEVPVGEELLGRVVNPLGQPIDGRGPIETSKTRPIESPAPGVMDRKSVHEPLQTGIKSIDSMIPVGRGQRELIIGDRQTGKTSIAIDTIINQKDQDMICIYVAIGQKESTVAGVVETLRQHGALDYTIVVSASASEPAPLLFLAPYAGVSMGEEFMYNGKHVLVVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGGGSITALPFIETQAGDVSAYIPTNVISITDGQIFLQSDLFYSGVRPAVNAGLSVSRVGGSAQIKAMKKVSGTLRLDLAAYRELEAFAQFGSDLDKATQAKLNRGQRTVEVLKQGLHEPLPVEKQVAIIYALINGFLDDIPVGDVRRFESELFTFLDHNKKELLDHIRTTGNLPDDSEFKAAITEFKQGFVTTK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: LEU3_PSEAE
Sequence: MSKQILVLPGDGIGPEIMAEAVKVLELANDRFQLGFELAEDVIGGAAIDKHGVPLADQTLQRARQADAVLLGAVGGPKWDRIERDIRPERGLLKIRSQLGLFANLRPAILYPQLAAASSLKPEVVAGLDILIVRELTGGIYFGQPREQRVLENGERQAYDTLPYSESEIRRIARVGFDMARVRNNRLCSVDKANVLASSQLWREVVEEVAKDYPDVELSHMYVDNAAMQLVRAPKQFDVMVTDNMFGDILSDEASMLTGSIGMLPSASLDANNKGMYEPCHGSAPDIAGQGIANPLATILSVSMMLRYSFSQATAADAIEQAVSKVLDQGLRTGDIWSEGCRKVGTREMGDAVVAALKNL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I13R1_HUMAN
Sequence: MEWPARLCGLWALLLCAGGGGGGGGAAPTETQPPVTNLSVSVENLCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNLSYMKCSWLPGRNTSPDTNYTLYYWHRSLEKIHQCENIFREGQYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIGKKRNSTLYITMLLIVPVIVAGAIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQTKEETDSVVLIENLKKASQ
What is the function of this protein?
Binds with low affinity to interleukin-13 (IL13).  Together with IL4RA can form a functional receptor for IL13.  Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
What are the official names of this protein?
Interleukin-13 receptor subunit alpha-1, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, Cancer/testis antigen 19, CT19.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 5 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NTPPA_PYRFU
Sequence: MKKIILASSSPRRREILSRFFDIIVHPSNVNEDKIKEKDPTETAIKIAKAKAFDLAVKFPTDTIIAADTIVTLNGKILGKPKDSEEARKMLKQLSGKTHEVVTGYCIISGDKIIEGAEITKVKFRELSDDLIEWYISTQEWRDKAGGYGIQGFGAILVEHIEGDYYNVVGLPIIVIIKLIELGHKLKRIF
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADTRP_MOUSE
Sequence: MTKTTTCVYHFLVLNWYIFLNYHIPQIGRNEEKLREFHDGGRSKYLTLLNLLLQAIFFGVACLDDVLKRVIGRKDIKFVTSFRDLLFTTMAFPISTFVFLVFWTLFHYDRSLVYPKGLDDFFPAWVNHAMHTSIFPFSLFETILRPHNYPSKKLGLTLLGAFNFAYIIRILWRYVQTGNWVYPVFDSLSPLGIIIFFSAAYILVAGIYLFGEKINHWKWGAIAKPQMKKN
What is the function of this protein?
Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids (By similarity).  Shows a preference for FAHFAs with branching distal from the carboxylate head group of the lipids (By similarity).  Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro) (By similarity).
What are the official names of this protein?
Androgen-dependent TFPI-regulating protein, Fatty acid esters of hydroxy fatty acids hydrolase ADTRP, FAHFA hydrolase ADTRP.
What is the protein family that this protein belongs to?
Belongs to the AIG1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalized with TFPI and CAV1 in lipid rafts.
Protein: CRBA1_HUMAN
Sequence: METQAEQQELETLPTTKMAQTNPTPGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEISDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin A3.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: SHO1_METRA
Sequence: MEHSRPYGGRKRMSLGNILGDPFALATISISLLAWFITFISCVIAQVQANKNKGLPDKDNPDGNFPPFAWWAVVYSLFLIVGVVIVVASDAIQTYHVAVTGYLAGGMVLVTSGVNSLVYSKNGAREAAAAGFILLSMVVIVWIFYFGSTPSSTPRAFLDSFALSKDSGAMHNQAMNGYGGTGRPETSNSVQPPQMYTSAQLNGFENPSPVGGASQAPTAPTMPTYGNNTMQPNNKSNDEEVLPPIDYPYQAKAIYSYEANPSDANEISFSKHEILDVSDVSGRWWQARRRGTNEIGIAPSNYLILL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.  Affects fungal virulence.
What are the official names of this protein?
High osmolarity signaling protein MOS1, Osmosensor MOS1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM1_BURP6
Sequence: MDMQLLTIGINHHTAPVALRERVAFPLEQIKPALSTFKSVFLGHPAPNAPEAAILSTCNRTELYCATNDRAARDAAIRWMSDYHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKNAVRTASEAGSLGTYLNQLFQRTFAVAKEVRGTTEIGAQSVSMAAAAVRLAQRIFEQVAQQRVLFIGAGEMIELCATHFAAQGPRELIVANRTAERGAKLAERFGGRAMPLADLPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDARSIVPVIRHMHTQADALRRAEVERARKMLARGDDPDAVLDALSQALTNKLIHGPTSALNRANGADRDSLIDLMRGFYQHAPRSSDTSDR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SELD_DESVH
Sequence: MTVDRLTSRSRAAGUAAKIAPGDLERILATLPRDPREGERVVVGTRDNEDAAIVRVPGGKAIVQTLDFFTPIVDDPYLFGQIAAANALSDVYAMGGEPWCALNIVCFPVKELPEDILADILRGGADKVREAGAVLVGGHSIEDESIKYGLSVTGIIDPDCYATNTGLRPGDVLLLTKPLGSGVLATAVKAGWDGFEAHEQELGRWGAMLNRAGGRVIRELGLAAATDVTGFGLGGHLLEMANASNMSVHVDVSTLPLMPAVLDLVATGLLPAGSHANRHFCSGNVSVHPEVDSLLVDIVFDAQTSGGLILAVPPHLVDDACSILRAEDAPFWRIGHVEEMGEGVPRLVLQP
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: UPP_STRPF
Sequence: MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEVSRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGMYRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCLVAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RPPH_AERS4
Sequence: MIDGDGFRPNVGIVICNRDGQVLWAKRYGQHSWQFPQGGVDDGETPEQAMYRELYEEIGLKPEDVTIMATSRNWLKYRLPKRLVRWDSSPVCIGQKQKWFLLQLDPGRESRIQFGCHGHPEFDDWRWVSFWYPVRQVVSFKREVYRRVMTEFAPLAMPVPVVQVNRKDGRRNRSR
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.