PharMolix/UniProtQA huggingface dataset:
Protein: PO2F1_XENLA
Sequence: MKLHSSSKIQNHAWLSDARMNNPSETSKSPESGDGNTGTQTNGLDFQKQAVPIGAITSAQAQALLGHLHQVQLAGTSLQAAAHSLNVQTKFKEEPGEPMQVVQPSQQPSLQAAIPQTQLMVAGGQIAGLTLTPAQQQMLLQQAQAQLLAAAVQHSASQQHNAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQYVLVHPTTNLQSAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPVQQLPQSQTTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENITSDSTLTNQSVLNSPGHGMEGLNRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGGSSSSPIKSLFSSPNPLVASTPSLVTSSPATTLTVNPVLPLTSAAAITSFHIPGTTGTSSANTATVISTAPPVSSVLTSPSLSSSPSATAASSEASTAGETSTTQTTSTPMTSSLNTGQVMVTASGIHTAAATALQGAAQLPTNASLAAMAAAAGLNPGLMAPSQFAAGGALFSLNPGALGSALSPALMSNSTLATIQALASSGSLPITSLDAAGNLVFANAGGTPNIVTAPLFLNPQNLSLFTSNPVSLISAASAGATGPITSLHATTSSIDSIQNALFTMASASGAASTTTSASKAQ
What is the function of this protein?
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes of some small nuclear RNAs (snRNA) and histone H2B (PubMed:2017364).  In vitro does not bind to variant octamer sequences, such as the H2B octamer 5'-GTTTGCAT-3', although binding has been observed in vivo during early embryogenesis, suggesting that interactions between pou2f1 and other factors might be required for octamer-dependent H2B transcription (PubMed:1990276, PubMed:2017364, PubMed:1406629).  Acts downstream of Notch signaling during radial glia formation (PubMed:18241856).  May be important for gastrulation, possibly through the regulation of an FGF-type signaling pathway (PubMed:7542467).
What are the official names of this protein?
POU domain, class 2, transcription factor 1, Octamer-binding protein 1, Oct-1, XOct1, Octamer-binding transcription factor 1, OTF-1, Xloct1-32.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Retained in the cytoplasm during early development, then gradually translocates to the nucleus around the mid-blastula transition (MBT).
Protein: UNG_SHIBS
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN16_ARATH
Sequence: MANYKGRGNVMIRSMLLGLYGIINIVCVNGTFINYKDALTKSLIFLEAQRSGKLPPNNRVPWRGDSALDDGKLVNVDLSGGYYDAGDNVKYGLPMAFTITTLAWSTITYEKELRATGELENARAAIRWGTDYFLKCASRKNRLYVQVGDPNADHQCWARPENMKTPRTVLEISDKVPGTEIAAEAAAAFAASSIVFRHVDHKYARRLLNKAKLLFKLAKSHKGTYDGECPFYCSNSGYNDELIWAATWLYKATRNHLYLSYLKFEAISAYVAEFSWDLKYAGAQILITKLIFEGHKGLDLYKQQADSFVCSNLPGSPYHQVFTTPGGMIHLRDGANSQYVTATAFLFSAYADILQKHNQKISCGSHQFDSTHLMAFAKKQIDYILGHNPQGRSYMVGFGPNPPKQAHHRGASVPMHEANAPLSCPLSFVKWYNKNVPNANELTGAILGGPDRQDKFQDLRWTSVYTEPCTYINSIAVGVLAKLAAA
What are the official names of this protein?
Endoglucanase 16, Endo-1,4-beta glucanase 16.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM6_POLSJ
Sequence: MSMTELSGVRTFLLGLQERVTAAVAEVDGGDFITDAWQKEPGEPLQGNGITKILENGEVFERAGCGFSHVQGSRLPPSATQHRPELAGAPFEAMGVSLVFHPRNPYVPTVHMNVRMLAATPVSAGPAEAVCWFGGGMDLTPYYGFDEDAVHFHQTCKDALAPFGGDKYPRFKQWCDEYFYLKHRQEQRGIGGIFFDDFQELGLEQSFAMMQSVADSFLPAYLPIVRRRQSQPYGARERDFQLYRRGRYVEFNLVWDRGTHFGLQSGGRTESILMSMPPLASWSYQHRAEAGSPEERLYKEFLIRRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_METCA
Sequence: MANIASAKKRARQAENNRAHNAALRSRLRTYIKKVILAVDSGDLTKAQEAFRQAVPIIDSSVNKGLIHRNKAARSKSRLNARVKALALQAAS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS18_ACICJ
Sequence: MSDSIETAPVNTPAARRTAVGARRPFYRRRKACPFSGPNAPKIDYKDVRLLSRFLSERGKIVPSRITAVSAKKQRELARAIKRARFLALLPYVVD
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y396_MYCLE
Sequence: MSEHNPAGAPGASTEVRVAIVGVGNCASSLVQGIEYYQNADDTSTVPGLMHVRFGPYHVRDVKFVAAFDVDAKKVGVDLSDAIFTSENNTIKIADVPPTNVVVQRGPTLDGIGKYYTDTIELSDVPPVDVVQALTEAKTDVLVSYLPVGSEEADKFYAQCAINARVAFVNALPVFIASDPVWAKKFADARVPIVGDDIKSQVGATITHRVMAKLFEDRGVQLDRTMQLNVGGNMDFLNMLERERVQSKKISKTQAVTSNVHREFNTKDIHIGPSDHVGWLDDRKWAYVRLEGRGFGDVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASSYLMKSPPQQLPDEIARAQLEEFIIDTK
What are the official names of this protein?
Uncharacterized protein ML0396/ML2692.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
Protein: PCKA_LEPBA
Sequence: MSVSTNLKGLAELGLKPSEVFHNLSYEEIYQHELNNKEGVTSDNGTMMVDTGIFTGRSPKDKYFVDEPSSQNNIWWGPVNTKVSEAIFNELYAEVTKFLDNKKLYVFDGHAGTNDDTRISLRVVTERAWQHHFCTNMFLRPTKEELAKLDPEFTIINASGYKNPKYKEHGLNSEVFVIFHLAKKICIIGGTEYGGEMKKGIFSVMNYYLPLKNVLTMHCSANVGKDGDSALFFGLSGTGKTTLSTDPNRKLIGDDEHGWDDNGIFNIEGGCYAKTINLDPKTEPEIYAAIRRDALLENVVYDATTKKVDYSSAAKTENTRVSYPIFHIDNIQPGSKAGHPNTVIFLTYDAYGVLPAVSKLSIEQAMYHFLSGYTAKVAGTERGVKEPQATFSACFGQAFMTLHPTYYAKLLGEKMKKHQVNAYLINTGLVGGKYGVGKRMNLPATRQIINEILNGNIEKSEFEKHPVFQVSFPKSVNGVDAHILNPRNAWENKEDYDKTAADLAKQFVENYKKYLTGSKEFDYSQYGPIA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP315_DROME
Sequence: MTEKRERPGPLRWLRHLLDQLLVRILSLSLFRSRCDPPPLQRFPATELPPAVAAKYVPIPRVKGLPVVGTLVDLIAAGGATHLHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQYPQHPLPDAWTLYNQQHACQRGLFFMEGAEWLHNRRILNRLLLNGNLNWMDVHIESCTRRMVDQWKRRTAEAAAIPLAESGEIRSYELPLLEQQLYRWSIEVLCCIMFGTSVLTCPKIQSSLDYFTQIVHKVFEHSSRLMTFPPRLAQILRLPIWRDFEANVDEVLREGAAIIDHCIRVQEDQRRPHDEALYHRLQAADVPGDMIKRIFVDLVIAAGDTTAFSSQWALFALSKEPRLQQRLAKERATNDSRLMHGLIKESLRLYPVAPFIGRYLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQPERVLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRVALKQLHSLLGRCAAQFEMSCLNEMPVDSVLRMVTVPDRTLRLALRPRTE
What is the function of this protein?
Required for CNS development: midline glial cells.  Involved in the metabolism of insect hormones: responsible for ecdysteroid C2-hydroxylase activity.  May be involved in the breakdown of synthetic insecticides.
What are the official names of this protein?
Cytochrome P450 315a1, mitochondrial, CYPCCCXVA1, Protein shadow.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: C2G1P_HUMAN
Sequence: MPYTDVVIHEIQRLVDIVPMGVPHNIIQDTQFRGYLLPKGTDVFPLLGSVLKDPKYFRYPDAFYPQHFLDEQGRFKKNEAFVPFSSGKRICLGEAMARMELFLYFTSTLQNFSLCSLVPLVDIDITPKLSGFGNITPTYELCLVAR
What are the official names of this protein?
Putative inactive cytochrome P450 2G1, Cytochrome P450 2G1 pseudogene.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: Y1320_NATPD
Sequence: MSRSALVGNITAMLEDAGFTVSDRCAIRPKSFDIAARRGDDVLLLKVLANIDAFDGYTGTEMRRLGEYLDATPLVIGLRTRDEELKPGVVYFRHGVPVFSPDTAMDLFIEEVPPLIYAAPGGLYVNIDGDLLSDIRSQEDMSLGKLANELGVSRRTVSKYEDGMSASVEVAAELEEIFDRKLASPVEVLSGAEEVRDDVDEPEAPEADPDDAEIVTVLTRVGFEVHPTMQAPFKAVSEDEKRERKVLTGHSEFNRTAEKRARIMSSVGHVTRTRSVYVVDSTKRDSVDGTALIEREEFERIHDSDELENLIRERAEG
What are the official names of this protein?
Putative HTH-type transcriptional regulatory protein NP_1320A.
Protein: MURJ_HELPJ
Sequence: MANILGAGVYSDIFFVAFKLPNLFRRIFAEGSFSQSFLPSFIRSSIKGGFASLVGLIFCGVLFMWCLLVALNPLWLTKLLAYGFDEETLKLCTPIVAINFWYLLLVFITTFLGALLQYKHSFFASAYSASLLNLCMILALLISKEKTHLEALYYLSYGVLLGGVAQILLHFYPLVKLGLWDLLFKGLLGFKTKNTNKKEYRLNRAKKDLKAFFKQFFPSVLGNSSAQIASFLDTTIASFLASGSVSYLYYANRVFQLPLALFAIAISTALFPSIAIALKNNQQDLILQRLQKAWFFLVGVLLLCSIGGIMLSKEITELLFERGQFSPKDTLITSQVFSLYLLGLLPFGLTKLFSLWLYAKLEQKKAAKISLISLFLGLAASLSLMPLLGVLGLALANSLSGLFLFVLTIKAFGFQSFLGIIKNLKSWLVILFLACVEILLLLAFKSWVTHLYLFYYFQGF
What is the function of this protein?
Involved in peptidoglycan biosynthesis.  Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
What are the official names of this protein?
Probable lipid II flippase MurJ.
What is the protein family that this protein belongs to?
Belongs to the MurJ/MviN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPD_ACIF2
Sequence: MERVWVVIPAGGRGQRFGAAQAKQYVLLRDRPVIAHTLAAFLGEPRIAGIQLVLPGEDIATGAWRELLGPMPAPLLPPVVGGGLRADSVRLGLEALLRQGAVPSDWVLVHDAARPCLRREDLLRLLESLANAPQGALLAVPVADTLKRGEDGCSSGTVDREGLWRALTPQAFPLGALLAALEAARAGNRQITDEASAMEAQGWRPRLIPGHGDNIKVTLSDDLMLAAAILAARSEEG
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: ATPB_AEGCO
Sequence: MRTNPTTSPPGVSTIEEKSTGRIDQIIGPVLDVTFPPGKLPYIYNALVVQSRDTADKQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDSSATFPIHRSAPAFIELDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIEESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERIASTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLDSTSTMLQPRIVGNEHYETAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVALAETIRGFQLILSGELDGLPEQAFYLVGNIDEASTKAITLEEENKSKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HBB_MESBR
Sequence: VHLTDAEKNLVSGLWGKVNADAVGAEALGRLLVVTPWTQRFFEHFGDLSSASAVMNNPQVKAHGKKVIHSFADGLKHLDNLKGAFSSLSELHCDKLHVDPENFKLLGNMIIIVLSHDLGKDFTPSAQSAFHKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SSRP_SYNR3
Sequence: MAGKGKGAKAAAKKRLEAQKLLADNRQARHQYEILDTLETGIELLGTEVKAIRAGKANLRDGFCLIRQGQLQLHNVHIAGHEQASRYFNHEPLRVRRLLAHRREIDKLRGQLDTKGLTLIPLNIHLKGSWIKLTIGLGKGRKLHDKRQEERRKQDQKDLRSALKRL
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SMC_SYNP6
Sequence: MVYIKQIELSHFKSFGGTTSLPLLPEFTVVTGPNGSGKSNILDALLFALGLSSSKGMRADRLPDLVNSTYASRSRSTVETLVTVTFALDDWQPEAEETEEGEGTGLQPGMAEWTVSRKLRVTPSGTYTSTYAMNGEACTLQQLHEQLSRLRIYPEGYNVVLQGDVTNIISMSPRDRRQIIDELAGVAQFDRKIEQAKGKLEAVKEREDRCRIVEQELIEQRDRLAKDREKAQKYQALRQEQATKQSWEAVLRWRAGQRQVQALQRSLAQLATDAATDQQTQQTLEQQIQQTEATLDRLNQRVKALGEEELLKLQAALAQQEAEQRQSQRQQQELVESQTQTQQQIQALLQTQAQLQTEGQQQAEQARTLQTTIAQTLQPQYQQALEQVEAARQSAHALAAQSQDWVTRQTSLRQQADAIAAQVEPQRAEQAQLQERQTQLQQQLEATQSALVTVTAELETETEQAEGDRAALSQAEAAVVTAADQLVRLEEELQIQQETRDRLLKEQRDKQRQLDRQESLRQAMQETQGTAAARLILDTGLPGVHGLVAQLGRVEPRYQLALEVAAGGRLGYLVVDDDGVASAGIELLKQKKAGRITFLPLNRIRAGKQPEIPRWQQPEGLVDLAIALVDCDDRYREVFKFVLGGTVVFERLDQARRYMGQYRIVTLDGELLETSGAMTGGSIARRSGGLSFGSPDSGESAEVRAIRDRLEQLEVILDRSELQILNLQAAIKDAASTLSDRRQQQREQQLTVQQRQQTLQRLQQQQQQLNAELQQRQQQASQAQARLAALALELPAALKQLKTLRQALAELEDSPIHGEWQQRQTLLQQQEALLQQQETALRQAEQQLQQLQTDQKRLQERAIAARTQVSQLRQQQGEQLNRLAQLDEQQRQQATAIAQLQQRQAQLEAQLGQEKVDRDRTERQLQEQRSQRQNLVWQQEKRQQQQQELQQQLTDLEVQLQAEQQELPQPLPDIPEMVQQQGIEALQHELRSLAKRIQAMEPVNMLALEEYERTQARLEELSEKLTTIEAERTELLLRIENFTTLRRRAFMESFEAIDRNFQEIFAHLSDGDGSLQLDNPEDPFSSGLNLIAHPKGKPVRRLASMSGGEKSLTALSFIFALQRYRPSPFYALDEVDSFLDGANVERLARVIRQQAQAAQFIVVSHRRPMIEAAERTIGVTQARGAHTQVLGIPQP
What is the function of this protein?
Required for chromosome condensation and partitioning.
What are the official names of this protein?
Chromosome partition protein Smc.
What is the protein family that this protein belongs to?
Belongs to the SMC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDD_KLEP3
Sequence: MHSRFQAALTTLAADLQAAIAPMLADPHFPALLEADQVATLQQATGLDEDALAFALLPLAAACARADLSHFNVGAIARGVSGRWYFGGNMEFLGATMQQTVHAEQSAISHAWLRGETSLRAITVNYTPCGHCRQFMNELNSGLALRIHLPGREAHALEHYLPDAFGPKDLEIKTLLMDAQDHGFPVSGDALTQAAIQAANRCHAPYSHSPSGVALELKDGTIFSGSYAENAAFNPTLPPLQGALNLLSLNGYDYPAIQRAILAEKADAALIQWDATVATLKALGCQNIERVLLG
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: ISPF_CITK8
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYDKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKAAK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: Y636_HAEIN
Sequence: MAIQTEKPIECVGCNTFDMKSLFDNRDCSQVIEYIYDSEGQAQEALAFFTQKARDVESEPCEIQSEITKVDDGYLLKADFTFCCQAELVIFQMRIA
What are the official names of this protein?
UPF0381 protein HI_0636.
What is the protein family that this protein belongs to?
Belongs to the UPF0381 family.
Protein: CPFB3_XENBO
Sequence: GLGSLLGSLFKFIPKLLPSIQQ
What is the function of this protein?
Has antibacterial and antifungal activity.
What are the official names of this protein?
Caerulein precursor fragment B3, CPF-B3.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS5_LISMC
Sequence: MIVIIDYDTGNTKSISKALDFIGLQNKISSDKTEIAQADGVILPGVGAYPEAMQELTRRGLDKTLKEIATAGKPILGVCLGMQLLLESSNEHSYTKGLGLIPGHVEMLPDESEFAVPHMGWNQLQIKRTTPLTQNIAGEYVYYVHSYYANCPEAYIIATSGYSIDIPGMINNGNIYGAQFHPEKSGQIGLEILKGFKEVIRSCKSSQQ
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_CLOTE
Sequence: MSIFKGSGVAIVTPFCENGVNFKKLEELIEWHIENSTDAIVICGTTGEASTMTEAEIKETIKFTVDKVQGRIPVIAGTGSNNTRKAIELSKWAKSIGVDGLLLITPYYNKTTQKGIVEHFKAINDDVDVPIILYNVPGRTGLNILPKTLVKICDTCSNVVAIKEASGDLSQIIEMKALLKDRIDIYSGNDDQIIPILSIGGIGVISVLANIMPKEVHDMCELYLKGKTKKALEIQLNTLSLTNSLFIETNPIPVKTAMNIMGIDVGELRLPLCNMDESNLNLLKKELSNHALIK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H16A6_CYRHA
Sequence: MNTVRVTFLLVFVLPVSLGQADKDENRMEMQEKTEQGKSYLDFAENLLLQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1a, U11-TRTX-Hhn1a, Hainantoxin-XVI.6, HNTX-XVI.6, Peptide F4-19.87.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FIS_ECOUT
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: GACA_DICDI
Sequence: MGSSSSKSSSSVTVASSIDYKAKPTIDELGTSNYSGGLEVSKNLLDFNLGEKPCPLKSVVQDQFTISNSSKTKLKFHFEPLQPKEFQLSFSPTSGSLDKGKSKTIKVKLMVNQKINTNHKVVLRVEGGASHFLTVKIRCETGVFGVDPNTLEHVEDEGFRVPYILALMKRSLIDNGGLQQEGIFRLAGEQTEIKRLKEAMNRNDFTSSTDINTVASLIKIWYRELPTPILNSIPTEKIFYSTDIDECVQSAKNLPEPQKSLLDWLMHLLLMVSSFSDVNKMTAQNLAIVVAPNLYDVSSSNPMEGLVLSQKCVQFLHNVLSHKVAVHKRESVAYEVLS
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacA, GTPase activating factor for raC protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_BRADU
Sequence: MAAKTKFRGSFTALVTPFKNGSLDEAAFRSLVNWQISEGTNGLVPVGTTGESPTLSHDEHKKVVEWCIEEAKGRVPVVAGAGSNSTKEAIELAQHAEKAGADAVLVVTPYYNKPTQEGMYQHFKAINDAIGIPIIIYNIPPRSVIDMSVDTMKRLWELKNIAGVKDATASMVRVSQQRAAMGEDFNQLSGEDATILGYMAHGGHGCISVTSNVAPRLCSEFHTAWQKGDHATALKLHDKLMPLHNNLFIESNPAPIKYAMSLLGKLDETLRLPMVPVTEPTRVAVRSAMVHAGLIN
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOSL1_RAT
Sequence: MYRDFGEPGPSSGAGSAYGRPAQPQQAQTQTVQQQKFHLVPSINAVSGSQELQWMVQPHFLGPSGYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEEDKKDTGGTSSTSGAGSPPGPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCSSAHRKSSSSSGDPSSDPLGSPTLLAL
What are the official names of this protein?
Fos-related antigen 1, FRA-1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Fos subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSX1_SAGOE
Sequence: MTSLPLGVKVEDSAFGKPAGGGSGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESSLAASESAQAAGGLAQPLGVPPGSLGVPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT
What is the function of this protein?
Acts as a transcriptional repressor.  May play a role in limb-pattern formation.  Acts in cranofacial development and specifically in odontogenesis (By similarity).
What are the official names of this protein?
Homeobox protein MSX-1, Msh homeobox 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HFQ_BARQU
Sequence: MAERSQHLQDVFLNTVRKQKISLTIFLVNGVKLTGIVTSFDNFCVLLRRDGHAQLVYKHAISTIMPGQPVQMFEGESSE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PA2B3_PROFL
Sequence: MRTLWIMAVLLVGVDGSLVQLWKMIFQETGKEAAKNYGLYGCNCGVGRRGKPKDATDSCCYVHKCCYKKVTGCNPKMDSYSYSWKNKAIVCGENNPPCLKQVCECDKAVAICLRENLGTYNKKYTIYPKPFCKKADTC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that has low phospholipase A2 activity (By similarity).  Shows anticoagulant activities, strong myolytic activity, infiltration of polymorphonuclear cells, and edema in stromal tissues.  Induces cell death of Jurkat cells in a concentration dependent manner.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 BP-III, svPLA2, Basic protein III, BPIII, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.