PharMolix/UniProtQA huggingface dataset:
Protein: SCH21_STACH
Sequence: ASVTFWTLDNVDRTLVFTGNPGSAAIETITVGPAENTTVEFPGSWVGNWYAYPTDAEDVPGMLGEVQFGGWNGLTYFDVSAIVNPTDHDNVKQMWPAESRKPMSGCEVFPCDNAYWLPDDIQTKVTHEVDLWTTLGAGSTGLTF
What is the function of this protein?
Has exodeoxyribonuclease activity with lambda-DNA and salmon testes dsDNA.  No activity with circular plasmid DNA.  The physiological role of this enzyme may be to degrade environmental DNA, and thus mobilize nitrogen for uptake.
What are the official names of this protein?
Antigenic protein SchS21, 21 kDa secretory protein, Alkaline exodeoxyribonuclease, SchS21.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRG_POLAQ
Sequence: MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPLQHGEVFVTEDGAETDLDLGHYERFVSAKMRKSNNFTTGQIYESVISKERRGEYLGKTVQVIPHITNEIQAFVERGAKASHDGKADVAICEIGGTVGDIESLPFLEAARQMSLRLPLHSCAFVHLTLVPFISSAGELKTKPTQHSVQKLREIGIMPTVLLCRADRPIPNDERAKISLFSNVREEAVISVWDVDTIYKIPEMLQAQGMDDLICRELELNAKPADLSVWANLVYELANPKHEVTIGMVGKYVELTESYKSLIEALRHAGIHTHTRVNITYIDSEDIEKEGIDCLKDLDAILVPGGFGKRGTEGKIAAIRYARENQVPYLGICLGMQLAVIEFARHVANIVQANSTEFDADTESPVVALITEWLDREGRVEKRTNASDLGGTMRLGSQRCPVKPGTLAHRIYGAEVNERHRHRYEVNNTYVPKLEQSGLVISARTPNEMLPEMMELPDSMHPWFFGVQFHPEFTSTPRDGHPLFSAFIKAALIHQDATLKQVS
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: THIC_CORGL
Sequence: MTPTQNEIHPKHSYSPIRKDGLEVPETEIRLDDSPSGPNEPFRIYRTRGPETNPKQGLPRLRESWITARGDVATYQGRERLLIDDGRSAMRRGQASAEWKGQKPAPLKALPGKRVTQMAYARAGVITREMEFVALREHVDAEFVRSEVARGRAIIPNNVNHPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLQWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQALEKVNGVAADLNWEVFRDTIIEQCEQGVDYMTIHAGVLLAYIPLTTRRVTGIVSRGGSIMAGWCLAHHRESFLYEHFDELCEIFAQYDVAFSLGDGLRPGSLADANDAAQFAELKTIGELTQRAWEYDVQVMVEGPGHVPLNMIQENNELEQKWAADAPFYTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPGARAWDDAMSKARFEFRWNDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFGDQIAELGMPGVGDSSSAVASSGAREGMAEKSREFIAGGAEVYRR
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: HIS8_XYLFM
Sequence: MNAQTPTVLDLVRQELRSFAGYSSARSVALTGDLWLNANESAWPNPADSHATMRRYPEPQPPKLRQMLAALYGCLPEQVLIGRGSDEGIDLLVRAVCEPRRDPVLVTPPVFGMYAVSAQLQNAPLIQVPLVDDAAGFHADVPAIITAAQTSRAKLVFLCSPSNPVGAAIPLQQIETILQTLAGTALVVVDEAYGEFSDVPSVVPLLARYPHLVVLRTLSKAHALAAVRIGSVIADAHLVAVLRRCQAPYPLPTPCVSLAEQGLSAAALHVTAQRVAEIRAERERLRAALACLSGVRRVYPSQGNFLLVRFDDAEAAFQALYAAGVVVRDQRAAPQLHDALRLTVGTPEQNTRLLAVLRDIQAVPA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: EPMA_SALPK
Sequence: MSETATWQPSASIPNLLKRAAIMTEIRRFFADRGVLEVETPCMSQATVTDIHLFPFETRFVGPGHSQGMNLYLMTSPEYHMKRLLAAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCQPAESLSYQQAFQRHLEIDPLSADKTQLREAAAKLDLSNIADTEEDRDTLLQLLFTMGVEPHIGKEKPTFIYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQQPIDQNLLDALAAGLPDCSGVALGVDRLVMLALGAESLADVIAFTVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: RPOB_BURCH
Sequence: MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADVPATQRKPEGLQAAFTSVFPIVSHNGFARLEFVSYALSSPAFNIKECQQRGLTYCSALRAKVRLVILDKESPNKPVVKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMDEGAQLEFVPERLRGEVARFDITDRDGKVIVQKDKRINAKHIRDLEAAKTKFISVPEDYLLGRVLAKNVVDGDTGEVIASANDEVTESVLEKLREAGIKDIQTLYTNDLDQGPYISSTLRVDETTDKTAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEEAYDLSKVGRMKFNRRVGRDEIVGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVVDSKVTDQIDYLSAIEEGRYMIAQANAAIDENGQLIDELVSSREAGETMMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPVVGTGIERTCAVDSGTTVQAFRGGVVDYVDAGRIVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPIVKMGDKVSRGDVLADGASTDLGELALGQNMLIAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGDAFQRLARMLVGKVANGGPKKLAKGTKIDQAYLEDLDHYHWFDIRLADDEAAAQLEAIKNSIEEKRHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPLGVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLQRQAKIEELRTFLTKIYNESGRQEDLESFTDDEILELAKNLREGVPFATPVFDGATEEEMGKMLDLAFPDDIAEQLGMNPSKNQVRLYDGRTGEMFERRVTLGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLDRN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RK16_CUCSA
Sequence: MLSPKRTRFRKHHRGRMKGISYRGNSICFGRYAIQALEPAWITSRQIEAGRRAMTRNARRGGKIWVRIFPDKPVTLRPTETRMGSGKGSPEYWVAVVKPGRILYEMSGVAENIARKAISIAASKMPIRTQFITSG
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPMT_PSEPF
Sequence: MQPEFWHKKWESNQIGFHQLEVNPYLQRHWPDLAIPVQARVLVPLCGKSLDLLWLAGRGHQVLGVELSEKAVEDFFHEQQLQPQVSEQGDFKVYRADAVELWCGDFFSLTMADVAGCTALYDRAAVIALPPAMRERYAAHLQSILPACRGLLVTLDYDQSQMPGPPFSVDDAEVQRLLGSVWRVEMLEQQDVLGDSWKFVQAGVTRLEERVYRIRGV
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCHS_LYMST
Sequence: DNYWCPQSGEAFECFESDPNAKFCLNSGKTSVVICSKCRKKYEFCRNGLKVSKRPDYDCGAGWESTPCTGDNSAVPAVF
What is the function of this protein?
Anti-gonadotropic neuropeptide.  It also decreases the binding capacity of calfluxin to membrane-bound receptors of the albumen gland.  This leads to inhibition of the reproductive activities of the infected snail.
What are the official names of this protein?
Schistosomin.
What are the subcellular locations of this protein?
Secreted.
Protein: MSRQ_SHIBS
Sequence: MRLTAKQVTWLKVSLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSLFNRLRKQAHNKLSL
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WECG_PHOLL
Sequence: MELNNIPKYSIRGLNIWGFRDMAHFLDHIFQREQVKTGTMVAINAEKVLTAEEDTALSTLLSDAEYLYADGISIVRAIRRKYPDTEVSRVAGADLWEAIMERAGKEGTPIFLVGGKPEILKQTESKLRAQWNVNIVGSQNGYFTPEERNAVFERIHASGAVIVTVAMGSPKQEIFMRDCRKIHSNALYMGVGGTYDVFTGHVKRAPKAWQNLGLEWLYRLLSQPSRIRRQFKLLKFIGYYYSGRL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: LEPA_STRP2
Sequence: MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MMM1_ASPTN
Sequence: MNFQQSAIPPFSFLLSFTQGFLLGQLSVVLLIGAFIKFFIFGEAPPPPSRGLSHRASTHRRSNSIYTISTNEAGSRSLREKPSTSNVLRPVPSSSTNTRSILRKTYYGAIPTNPSKHGRHRVHHSSHQPESLDWFNVLIAQTIAQYRQTAYLLKDEPTSSILSSLTAALNNPEKKPSFIDKITVTDISLGEEFPIFSNCRIIAVDDPNSDGGRLQALMDVDLSDDNLSIGIETSLLLNYPKPGSAILPVALSISVVRFSGTLCISLVPASTPPLHTPSPSPAPQTADGARTQSQPENNSSNPNQQSADASGAPPKTSPKSNVAFSFLPDYRLDLSVRSLIGSRSRLQDVPKVAQLVEARVHAWFEERVVEPRVQVVGLPDLWPRMGRTGVRTGEDSETGSNAASRSAISADLGSSLRDDLDQGPDGLRFRGPLGARPQFDSVSRSSSFNVETGGFHGHPMTREDSRGAISDDFHMPGSLPDGAVGN
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: COAD_BACCQ
Sequence: MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATKDIPNVKVDSHSGLLVEYAKMRNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKFQTPLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_ANAD2
Sequence: MGDTRVTVIGGGLAGTEAAWQLARAGVAVELVEMKPERRSPAHVLPGLAELVCSNSLRSDNPLNAVGLLHEELRRLGSLVLGCADETRVPAGDALAVDRERFSEAVTARLTGHAGVRIVHRELEELPPPPALAVIATGPLTADALAARLAETTGGRLHFYDAIAPIVAAESIDRSIAYARSRYGKGSGDDYLNLPLDEAQYHAFVEALLQGEKVAAHGFEEPRYFEGCLPIEVMAERGLEVLAHGPLKPVGLEDPRTGRRPHAVVQLRREDVDGTAWNLVGFQTRLTWPEQRRIFRAFLPGLANAEFVRLGQIHRNTFVDAPRVLAPDLSVRAAPHLFLAGQITGVEGYVESAACGLMAARAVLDRLAGRAFRPPPPATALGALHRHLTGEAHPPGYDYQPSNVVFALFPPLTGRHRGKAGRKEAHVERARKELAPWIDSAPPTAVPAAPAAG
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_MESH7
Sequence: MFQTINEISIHPELYNQKKVLIQGWITNIRGNLKIIFVELNDGSSFKNLQCVLKKEFIDFDKIENLALGVAVEISGIFSNTPERQQFGEVLVETLEIKGNNYNTNFPIQNQEISLEVLRQMPHFRHRSRLFRAIMKLRSALFFEIHKFFRRQGFINFSAPILTSNDGEGAGEVFIVDDENKDFFNKKTTLGVTGQLHAEAYALGFKKVYTFAPTFRAERSNTRRHAAEFWMIEPEVAFFTLEQIIELAVKLLQKVIKSVIIRNKDEFIFLEKAGDKNLRKRLLQFCDSQVTQISYEKAIELLLEHQEKFEEKDLFFGCDLKTEHERFLTEEIFHMPVVIINYPKNLKAFYMHQNEDGQTVAAFDLLVPGIGELIGGSQREVRYEKLLARMNELNMNIEEFQWYLDLRKYGNPGSSGFGLGFERLLMYITGIENIRDVIPFPRTNKNILM
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YX_LYSSH
Sequence: MVRSDIIRGHLDSIILRLILEKDRYGYEISQEISNRTNNSFQIKEATLYAVFQRLEKKEVIEAYYGDVSDGGKRKYYRITSLGKAYLSELVKEWAEVKEIIDLFMEGLE
What are the official names of this protein?
Uncharacterized protein X.
Protein: AACA_ENTFC
Sequence: MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD
What is the function of this protein?
Involved in resistance to gentamicin, tobramycin, and kanamycin.  Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region.  The C-terminal region is a kinase that phosphorylates several 4,6-disubstituted aminoglycosides.
What are the official names of this protein?
Bifunctional AAC/APH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the aminoglycoside phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_ANAD2
Sequence: MADTWSIGAHAFTSRLLVGTGKYPDFPTMQRALAASGAEVVTVAVRRLDLSKKGEESLLAWIPKGMKLLPNTAACFTAEEAIRTARLGRELEMGDLVKLEVIGDRRTLFPDVEGLIQAAKVLVKEGFTVLPYTNDDPVTAKKLEDAGCAAVMPLGAPIGSGLGLRNPYNLRIIMETVQVPVLVDAGVGTASDAALAMELGAVAVLMNTAIAEAKDPVLMAEAMRAGVEGGRKAFLAGRIPMKLHAAASSPMSGLIGS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_CORGL
Sequence: MAEKGITAPKGFVASATTAGIKASGNPDMALVVNQGPEFSAAAVFTRNRVFAAPVKVSRENVADGQIRAVLYNAGNANACNGLQGEKDARESVSHLAQNLGLEDSDIGVCSTGLIGELLPMDKLNAGIDQLTAEGALGDNGAAAAKAIMTTDTVDKETVVFADGWTVGGMGKGVGMMAPSLATMLVCLTTDASVTQEMAQIALANATAVTFDTLDIDGSTSTNDTVFLLASGASGITPTQDELNDAVYAACSDIAAKLQADAEGVTKRVAVTVVGTTNNEQAINAARTVARDNLFKCAMFGSDPNWGRVLAAVGMADADMEPEKISVFFNGQAVCLDSTGAPGAREVDLSGADIDVRIDLGTSGEGQATVRTTDLSFSYVEINSAYSS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBRA4_RAT
Sequence: MVSVQKVPAIVLCSGVSLALLHVLCLATCLNESPGQNSKDEKLCPENFTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMQKAKKKISKPPPEVPAAPVLKEKHTETSLQNTHANLNMRKRTNALVHSESDVNSRTEVGNHSSKTTAAQESSETTPKAHLASSPNPFSRANAAETISAAARGLSSAASPSPHGTLQPAPLRSASARPAFGARLGRIKTTVNTTGVPGNVSATPPPSAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVVYLSKDTMEKSESLM
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit alpha-4, GABA(A) receptor subunit alpha-4.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA4 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: E3GAL_FLAVE
Sequence: MKLFVVLACLAAPGTFPFVDAATVIPANSFSSFSTYWNNFYPWGTDHNGSGRMASANIIVASNTLSLIATPTSNPSPPTSTSNPKPAIHYASGAIHAKEHITVTAANAYTVSGEFSAPTAVGTWPAFWLTAVSGWPPEVDIGEWKGTADNWFNTFNTSSVVKSTLVDWPTDLSFHSVKAVLTAQSNNKDVKIDFYMDNKFIVTQYGSGFVGKAMYLIINLQMEGSSGSPGPSGRTVYKARNVQVTRTGN
What is the function of this protein?
Specifically hydrolyzes beta-1,3-galactan in an endo-fashion.  Requires at least 3 contiguous beta-1,3-residues.
What are the official names of this protein?
Galactan endo-beta-1,3-galactanase, Endo-beta-1,3-galactanase, FvEN3GAL.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
Protein: RL4_BRUC2
Sequence: MDLTITTLEGKDAGKVKLNEEIFGLDPRDDILQRVVRWQLARRQQGSHKAQGRGDVSRTGSKMYKQKGTGRARHHSARAPQFRGGGQAHGPVVRNHDHDLPKKVRALGLRHALSAKAKASDLIIIDDLASADAKTKQLVSQFAKLGLENALLIGGAEIDANFQRAASNIPNIDVLPVQGINVYDILRRGKLVLSKAAVEALEERFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ATPL_HYPNA
Sequence: MEGNITDGLKYVGAGLATLGMIGSALGVGNIFASFLDAAMRNPSAAPQQTGNLFIGMALAEALGIFSVLIAILILFVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KA23N_VAEMS
Sequence: MKTSCLLTILLLSFLVAVAVAEGERSARAAAISCVGSPECPPKCRAQGCKNGKCMNRKCKCYYCG
What is the function of this protein?
Voltage-gated potassium channel inhibitor.  Selectively and reversibly binds (Kd=0. 77 nM) and blocks hKv1. 3/KCNA3 potassium channels of human T-lymphocytes.  Also shows a very weak effect on hKv1. 2/KCNA2 (Kd=7. 1 uM).  Also reduces the fraction of CD40L expressing T cells that are stimulated by alphaCD3/alphaCD28.
What are the official names of this protein?
Toxin VmKTx1, Toxin sVmKTx.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 23 subfamily.
Protein: RS21_SYNY3
Sequence: MTQVVVGQNEPIESALRRFKRQVAKAGIYTDFKKHQFFETPQEKHKRKEATRRRQRSRRR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CAPB_PSEFR
Sequence: MSNRQTGTVKWFNDEKGFGFITPQSGDDLFVHFKAIQSDGFKSLKEGQQVSFIATRGQKGMQAEEVQVI
What is the function of this protein?
Affects cell viability at low temperatures.
What are the official names of this protein?
Cold shock protein CapB, C8.0, Cold acclimation protein B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_CORGB
Sequence: MKQRNNAKRVRLEQTRRPKKNPLKAAGIEKVDYKDINTLRQFISDRHKIRSRRVTGLTPQQQREVATAVKNAREMALLPFTSR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TRPC_CAMJJ
Sequence: MILDKIFEKTKEDLKERKLKLPYDMLGRSLASNPFFPKDVIKALKRVEKEVKIIAEVKKASPSKGVIREDFDPLSIALNYEKNKATAISVLTEPHFFKGSLEYLSLIRRYTQIPLLRKDFIFDEYQILEALVYGADFVLLIAKMLSMKELKKLLEFARHLGLEALVEIHDKEDLSKAIFAGADIIGINHRNLEDFTMDMSLCEKLIPQIPNSKIIIAESGLENKEFLEHLQNLGVDAFLIGEYFMREEDEGKALKALL
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.