PharMolix/UniProtQA huggingface dataset:
Protein: NRDR_NITHX
Sequence: MRCPSCNSLDTQVKDSRPTEDSAVIRRRRVCMACNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLVRSLQISLRKRPVEPERVETMVSAIVRELESGGEAEISSEIIGEIVMEHLRSLDDVAYVRFASVYRNFREAKDFEAVLGELSSEDDARPVPLRK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: GPSM3_HUMAN
Sequence: MEAERPQEEEDGEQGPPQDEEGWPPPNSTTRPWRSAPPSPPPPGTRHTALGPRSASLLSLQTELLLDLVAEAQSRRLEEQRATFYTPQNPSSLAPAPLRPLEDREQLYSTILSHQCQRMEAQRSEPPLPPGGQELLELLLRVQGGGRMEEQRSRPPTHTC
What is the function of this protein?
Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins.
What are the official names of this protein?
G-protein-signaling modulator 3, Activator of G-protein signaling 4, G18.1b, Protein G18.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR2_BACSU
Sequence: MIKLCREVWIEVNLDAVKKNLRAIRRHIPHKSKIMAVVKANGYGHGSIEVARHALEHGASELAVASVEEGIVLRKAGITAPILVLGFTSLSCVKKSAAWNITLSAFQVDWMKEANEILEKEASANRLAIHINVDTGMGRLGVRTKEELLEVVKALKASKFLRWTGIFTHFSTADEPDTTLTKLQHEKFISFLSFLKKQGIELPTVHMCNTAAAIAFPEFSADMIRLGIGLYGLYPSAYIKQLNLVKLEPALSLKARIAYVKTMRTEPRTVSYGATYIAEPNEVIATLPIGYADGYSRALSNRGFVLHRGKRVPVAGRVTMDMIMVSLGENGEGKQGDEVVIYGKQKGAEISVDEVAEMLNTINYEVVSTLSRRIPRFYIRDGEIFKVSTPVLYV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase 2.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: BUD19_YEAST
Sequence: MTKSLKHKYVLRLDVHLGSSPVSSLSVVTDSVVGSQSDPLWQWSVLLLSLSHFLLDSERLLSLIKRETYRAHTKCTIVKNVSNNVQTHQYDAFTDPRQYHLT
What are the official names of this protein?
Putative uncharacterized protein BUD19.
Protein: DDL_LEGPH
Sequence: MSKPVNLVLLYGGKSGEHEVSLVSAASVLKHLDSEKYHIIPIAMDKSGRFHRHDYNDLLACSDKLPVVTEKSTPLEGLLINGRLAVDAKIVFPVVHGPLYEDGCLQGLLELAGVAYVGCDVLSSAIGMDKDMARRLACINGLKSARYKLLSWHANASERQQFCHEVASEFGWPLFVKPCSLGSSVGIHKANNMDELNAAVADALRYDEEILVEEFIVGREIELAVLENSIPCGKPRVSMVGEIKVNHPDGYYSYTAKYLESSQTDLIIPAQLNNSLEEQLKQAAANIFSYLKCKGMARVDFFVNDKTEEIYFNEINTLPGFTSISMYPKLWQATGIAYPDLLDELINLAMVHHNCRQHLVTNYL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCDX_SALHS
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAEAKRKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRLVDGVGILRGIEANIKNINGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKETNTQAMIATIASGKVHIISHPGNPKYPVEVKAIAQAAAKHHVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTLGDFTECRKILDAVNFPEDRILNVSPQCLLAFLESRGMAPVPEFAEL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: ISCA2_DICDI
Sequence: MIRSIFKKNSSLPYFLKRSFITKPHSIITPIINNNNHNNNNINTPIKNIQSFNFKFFTTTTTSNPIHQQTTTTTTTTPSTEQQQLSKEAEEINENITKYNITLTDSCVKELNSVQKKSDSTDIFLRVMVDMGGCSGYQYIIKVENKLQDDDVLFIRNGAKVIIDKISLEMMEGSIIDYETALMRSSFVVASNPNTIKSCGCKISFELKK
What is the function of this protein?
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway.  May be involved in the binding of an intermediate of Fe/S cluster assembly.
What are the official names of this protein?
Iron-sulfur cluster assembly 2 homolog, mitochondrial, Iron-sulfur assembly protein isca2.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARHG3_MACFA
Sequence: MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCEHMEQTDSSCGNSRHGESNV
What is the function of this protein?
Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_VIBC1
Sequence: MTDSPVLALAKDLISRQSVTPEDAGCQDVMIERLKALGFEIEVMVFEDTTNFWARRGTEAPLFAFAGHTDVVPAGKLEQWDTHPFEPTIIDGYLHGRGAADMKGSLACMVVAVERFIAENPDHKGSIGFLITSDEEGPFINGTVRVVETLMDRGENIDMCIVGEPSSTEVVGDVVKNGRRGSITGDLTVKGTQGHVAYPHLANNPVHQSLMAIHELATTEWDQGNDYFPPTSFQIPNVSAGTGASNVIPGEFNVQFNLRFSTELSNEVIVQRITETLDKHELDYDLKWTFNGDPFLTDTGALLDAVVAAVDEVNSTKPALLTTGGTSDGRFIARMGGQVVELGPVNATIHKVNECVKVDDLEKLTDMYENTLKHLLAK
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PA67A_BISBO
Sequence: RGSNLTHPLRNIGDLFYVGN
What are the official names of this protein?
Pregnancy-associated glycoprotein 67A, EbPAG-A 67 kDa.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: CWP25_SOLLC
Sequence: SNPNFILTLVNNVPYTIWPA
What are the official names of this protein?
23 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: LON_BUCAI
Sequence: MNSERSERITIPVLPLRDVVIYPHMVIPLFVGRQKSIKCIETSMSNDKKIMLIAQKEASKDEPTPKDLFDIGTISAILQMLKLPDGTVKVLIEGLQRAHIKNLTNNGEHFIAEVELISSSNLLDKNQEVLIRTTMNQFESYIKLNKKIPLEILNVLNNIKNSEKLADTIAAHMPLKLNDKQSVLEIRNINDRLEFLMAIMESEIDLLQVEKRIRHRVKKQMEKSQREYYLNEQIKAIQKELGDMDEIPDENKILKRKIKSSKMPKEAREKTELELQKLKMMSPMSAEATVVRSYIDWMIQVPWYLKTKIKKDLQQAKKILDIDHFGLETVKDRILEYLAVQSRKNKIKGPILCLIGPPGVGKTSLGKSIARSTGRKYVRIALGGIRDEAEIRGHRRTYIGSMPGKLIQKMAKAKVKNPLFLLDEIDKMSRDIRVDPASALLEVLDSEQNMNFNDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEIIRLSGYTEDEKLNIAKRYLYPKQIERNGLEENEIKITDSAIISIIHYYTREAGVRSLEREISKICRKAVKNLILDKSLKHIEINSKNLKKFLGIKRFDYGKIHGTNQIGQVIGLAWTEVGGELLTIETTCVSGKGKLTYTGSLGEVMQESIQAALTVVRSQADRLGIKKDFHEKHDIHVHVPEGATPKDGPSAGAAMCTAIVSSLTNNPVKSNVAMTGEITLHGKILPIGGLKEKLLAAHRGGIKTVLIPYENKRNLEEIPKNIIEGLNIHPIKKIEEVLKLSLEKIPYV
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18A_DICDI
Sequence: MPIHEFQVVGRHVPTERDANPKIYRMRLFAQTSIHAKSRFWYFLSKIVKMKKSTGEILNVTEIFEDKPQKVKNFGVFIRYNSRSGTHNIYKEYRDLTRCGAVSQMYDEMASRHSARESSIHIIDIKEIAASLTRRANTKQFHDSKIKFPLTHRIAKSKSTFVANRPNTFFC
What are the official names of this protein?
60S ribosomal protein L18a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: YFUM2_GEOSE
Sequence: MNYFRILYCSVLLFFSFFSCTSAAVSNHPIHWGFQKNNNHQPPDAGKEWNELLNKYGAFYLGDPSKKEIYLTFDNGYENGYTSKILDVLKKHDVHATFFVTGHYLKTAPDLVKRMVKEGHIVGNHSWSHPDMTTISADKIKKELDAVSDKVKELTGQEGTVYVRPPRGIFSERTLALSEKYGYRNIFWSLAFVDWKVNEQKGWRYAYDNIINQIHPGAIILLHTVSKDNADALDEAIKTLKQQGYTFKSLDDLVMEKMFESPFLY
What are the official names of this protein?
Uncharacterized 30.6 kDa protein in fumA 3'region, ORF2.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family.
Protein: ZN182_PONAB
Sequence: MAKPQGLVTFEDVAVDFTQEEWQYLNPPQRTLYRDVMLETYSNLVFVGQQVTKPNLILKLEVEECPAEGKIPFWNFPEVCQVDEQIERQHQDDQDKCLLMQVGFSDKKTVTTKSACDCHEFGNILHLSTNLVASIQRPDKHESFGNNMEDNLDLFSRSSAENKYDNGCAKLFFHTEYEKTNLGVKPYGYKECGKGLRRKKGLSLHQRIKNGEKPFECTACRKTFSKKSHLIVHWRTHTGEKPFGCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIHYRTHTGEKPHECNECGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKPHECNECKKAFSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVHQRTHTGEKPYECDVCGKTFTQKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKSYLIIHQRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECPVCWKAFSQKSQLIIHQRTHTGEKPYACTECGKAFREKSTFTVHQRTHTGEKPYKCTECGKAFTQKSNLIVHQRTHTGKKAHGRGHTRKSKFMAH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 182, Zinc finger protein 21.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMG_DEIRA
Sequence: MIPDALTPAGRELLRRGADDLGLDVAPHEEQFARLLALLRAGNERLNLTALKTEEDIVLKHFVDSLTTLRGGHLDGEWKTLDLGTGAGFPALPLAILRPELRLTPLDSIRKKIDFVRETAAELGLSNVTPQVGRAETLGQSAEHRGSYDRVVARAVAALPVLAELALPLLRVGGVFVAQKGPLSEEELDAGRRAAGEVGGRIIEVDPFTLPVSGDARTLIVLEKQRPTPAKYPRREGVPTHQPLFWKAKEQSR
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_SHIDS
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_PROMH
Sequence: MIPDVSKALSWLEAHPKVLCGIHRGIERETLRVTPDGHLAATGHPVELGKSLTHKWITTDFAESLLEFITPVDDNIDHTLHFLSDLHRYTARHLTNERMWPMSMPCFIEAEDKITLAQFGTSNVGRFKTLYREGLKNRYGALMQTISGVHYNFSLPIEFWQAWANITDEETGKEAISDGYLRLIRNYYRFGWIIPFFFGASPAICGSFLKGRKTNLPFENTPKGAKYLPYATSLRLSDLGYTNKSQSDLDITFNHLETYVKGLKKAIHKPSEEFAKLGVKKDGKYIQLNTNVLQIENELYAPIRPKRVVKGDESPSDALLRGGIEYIEVRSLDINPFTPIGVDETQIRFLDLFLIWCVLADAPEMNAEELACCRANWNNVILEGRKPGQVIGMGCGERKEPLAQVGKALFADLQRVAKVLDSCSGTKYLEVCLKLEEMFDNPQLTFSGRLLEKIKAQGIGGYGLSLAEEYHQQLVNTAYEVLTDDAFEHERISSIKRQADLEKSDTISFDEYLKLHAGPNNDGVAS
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: CH3L1_BOVIN
Sequence: MGLRAAHTGFVVLVLLQSCAAYKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLNTLKNRNPNLKTLLSVGGWNFGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGWRDKRHLTTLVKEMKAEFVREAQAGTEQLLLSAAVPAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSPLFRGQEDASSDRFSNADYAVSYMLRLGAPANKLVMGIPTFGRSYTLASSKTDVGAPISGPGIPGQFTKEKGILAYYEICDFLHGATTHRFRDQQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLTSAIKDVLARV
What is the function of this protein?
Carbohydrate-binding lectin with a preference for chitin.  Has no chitinase activity.  May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment.  Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation.  Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs.  Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells.  Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance.  Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung (By similarity).
What are the official names of this protein?
Chitinase-3-like protein 1, 39 kDa whey protein, Cartilage glycoprotein 39, CGP-39, GP-39, Chitinase-like protein 1, CLP-1, SPC-40, Signal-processing protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum.
Protein: PRMA_ECO55
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRNNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_SHISS
Sequence: MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: TSN19_HUMAN
Sequence: MLRNNKTIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFCDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKNIKNIIHAEM
What are the official names of this protein?
Tetraspanin-19, Tspan-19.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PG055_VAR67
Sequence: MGFCIPLRLKMLKRGSRKFSSMLARRHTPKKMNIVTDLENRLKKNSYIENTNQGNILMDSIFVSTMSVETLFGSYITDDSDDYELKDLLNVTYNIKPVIVPDIKLDAVLDRDGNFRPADCFLVKLKHRDGFTKGALYLGHSAGFTATICLKNEGVSGLYIPGTSVIRTNICQGDTIVSRSSRGVQFLLQIGGEAIFLIVSLCPTKKLVETGFVIPNISSNDNAKIAARILSEKRKDTITHIDTLIQYGQQLELAYYNSCMLTEFLHYCNLYANTIKESLLKETIQKDINITHTNITTLLNETAKVIKLVKSLVDKEDTDIVNNFITKEIKNCGGVKNRDTIVNSLSLSNLDFYL
What is the function of this protein?
Stimulates increases in peripheral microtubule dynamics and may increase the motility of the infected cells, contributing to cell-to-cell spread of the virus.  Seems to inhibit the signaling via the GTPase RHOA and DIAPH1/mDia.
What are the official names of this protein?
Protein OPG055, Protein F11.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG055 family.
Protein: MIA40_CANGA
Sequence: MVSAVSRQLVNRQLNRVLLRNARIAPFARATRFYSSKYAQESENAKRHKMGLLIAGVAVAGAIVFVTPPQWKKYFRAAKKVEEVAESKEDPVSEAAEEVSESVQESTEEPQQSQEKETADVGNEQAQDESASSGDSEAKKAHDEFADQNEASEKESAPMGESADADQTAKDETVAEKTGNSKSESSESDQSEQDILSSDLEETMETVSEADKELHQISDNTVLSSEEDKTPKAEELKSTSPSGNDEEPKKEDDSSKTIHSLNSEKDMEAVEEEVKQESAYNPDTGEINWDCPCLGGMAHGPCGEEFKAAFSCFVYSEAEPKGIDCVEKFQHMQDCFRRYPEHYAEQLADPADDENVDHEKNLSEGKDTGVDSTPPKDEAYLKTEKEKKIEENASPDEDTASKKD
What is the function of this protein?
Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS).  Forms a redox cycle with ERV1 that involves a disulfide relay system.  Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria.  The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS (By similarity).
What are the official names of this protein?
Mitochondrial intermembrane space import and assembly protein 40, Mitochondrial import inner membrane translocase TIM40.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass type II membrane protein; Intermembrane side.
Protein: PPIL3_CHICK
Sequence: MAVTLHTDVGDIKIELFCERTPKTCENFLALCASNYYNGCVFHRNIKGFMVQTGDPLGTGKGGTSIWGKKFEDEFSEYLKHSVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVFGKVIDGLETLDELEKLPVNEKTYRPLNDVHIKDITIHANPFAL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 3, PPIase, Cyclophilin-like protein PPIL3, Rotamase PPIL3.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily.
Protein: THIC_NITEU
Sequence: MKTPVSKLEKFTNDNARVDTAAVQPLPNSRKIYIQGSRADIQVPMREITQSDTATGRGAEKNPPIYVYDTSGPYTDPDTRIDIRHGLPPLREKWIDERGDTEILTGLSSSYSLKRLQDPALTKMRFNLMRPVRHARNGANVTQMHYARRGIITPEMEFIALRENQRRERVADLASNELLNRQHPGQSFGAIIQEWITPEFVRDEVACGRAIIPANINHPETEPMIIGRNFLVKINANIGNSALGSSIQDEVEKMTWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLPFIPMTAKRMTGIVSRGGSIMAKWCLAHHQESFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQFAELKTLGELTEIAWKHDVQVMIEGPGHVPMHLIRENMDLQLKYCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPDKDDVKDGIITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWNDQFNLSLDPDKAREFHDETLPQEGAKLAHFCSMCGPNFCSMKITQDVRDYAAQQGISETVALQEGMARKANEFIEKGGELYSKQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: HUGAB_VESVE
Sequence: SERPKRVFNIYWNVPTFMCHQYGLYFDEVTNFNIKHNSKDNFQGDKIAIFYDPGEFPALLPLKYGKYKIRNGGVPQEGNITIHLQRFIEHLDKTYPNRNFSGIGVIDFERWRPIFRQNWGNMKIYKNFSIDLVRKEHPFWNKKMIELEASKRFEKYARLFMEETLKLAKKTRKQADWGYYGYPYCFNMSPTNFVPDCDVTAMRENDEMSWLFNNQNVLLPSVYVRRELTPDQRIGLVQGRVKEAVRISNNLKHSPKVFSYWWYVYQDETNTFLTETDVKKTFQEIVINGGDGIIIWGSSSDVNSLSKCMRLREYLLTVLGPIAVNVTEAVN
What is the function of this protein?
Hydrolyzes high molecular weight hyaluronic acid to produce small oligosaccharides.
What are the official names of this protein?
Hyaluronidase B, Vesp v 2B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM6_ORYSJ
Sequence: MAPSLLTTPSQALALAPGAAASRVGGGGGGSARVSFPSGRVQRRGALGMRVRASVAIEKETPESEPPPTFLREDGSGAGSGSVRERFEAMIRRVQGEVCAALEEADGSGARFVEDVWSRPGGGGGISRVLQDGRVFEKAGVNVSVVYGVMPPDAYRAAKGEAGKNGAAADGPKAGPVPFFAAGISSVLHPKNPFAPTLHFNYRYFETDAPKDAPGAPRQWWFGGGTDLTPSYIIEEDVKHFHSVQKQACDKFDPSFYPRFKKWCDDYFYIKHRNERRGLGGIFFDDLNDYDQEMLLNFATECADSVVPAYIPIIERRKDTPFTEEHKAWQQLRRGRYVEFNLVYDRGTTFGLKTGGRIESILVSLPLTARWQYDHTPEEGTEERKLLDACINPKEWLDL
What is the function of this protein?
Involved in the heme and chlorophyll biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (By similarity).
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, chloroplastic, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RIMP_BURTA
Sequence: MQLTELIETTVTGLGYELVDLERTGRGMVCVYIDQPAGITIDDCEKVTRQLQHVLTVENIDYERLEVSSPGLDRPLKKLADFTRFAGSEAVITLKKPLDGRKTYRGILHAPNGETIGLEFERKKGEAAMLDFTLADIDKARLIPHVDFRSRKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDD_SALTI
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMSGEELGDIEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVAAVNLWFLESGKSGIFNLGTGRAESFQAVADATLAYHKKGSIEYIPFPDKLKGRYQAFTQADLTNLRNAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: METE_SODGM
Sequence: MAILSHTLGFPRVGLHRELKKAQESYWAGNISQQQLLETGRELRARHWQQQKDAGVDLLPVGDFAWYDHVLTTSLMLDNVPARHRSGANESDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFTLGQQFRLGWTQLLDEVDEALALGHRVKPVLLGPVSYLWLGKVKGEAFDRLSLLPALLPVYKQVLGELAKRGVDWVQIDEQALVLELPQAWREAYREAYQALQGQTKLLLTTYFDSIRHQLDIITALPVQGLHVDLVAGDDDLTELHRQLPAEWVLSAGVINGRNVWRADLQSWFEQLRPLLGKRELWLGSSCSLLHSPIDLSTETQLDEEVKSWFAFALQKCAELGLLRAALNAPDEANQARLGEYSAPIRARRHSSRVHNPEVKARLEKITAADSQRQQPYAARAALQRARFKLPAWPTTTIGSFPQTTEIRGLRLDFKRGRLDGGHYRTGISEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIIIGDISRPEAITIEWARYAQSLTAKPVKGMLTGPVTILCWSFPREDVSRKTIARQIALALRDEVADLEQAGIGVIQIDEPALREGLPLKHSAWQDYLTWAVEAFRLNAAVAQDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLETFKEFDYPNEIGPGVYDIHSPNVPSEEWIVELLRKAAQRIPAERLWVNPDCGLKTRAWPETRQSLANMVTAARKLREEQP
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.