PharMolix/UniProtQA huggingface dataset:
Protein: RK3_CYACA
Sequence: MKNVDFCTFGVKLGMTQILDNFGNLVPVTIVSQPKPCVITRVTTSLNSQQKLIIQIGCYSDFRANKPTIGYFKKQSVPNLRYLHEFQTYKNNEYQVGKSLDLKELDQQLVQVSAYTIGKGFAGYQKKHKFSRGAMSHGSKSHRRPGSIGAGTTPGRVFPGVKMAGRLGFSRRSIKNLLVLKVDLTNKLFLLKGSVPGKYGNLLLVSLKKTNYFLD
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NIR_MAIZE
Sequence: IPGRTGRARAAVSVPPPAGEQVPTERLEPRVEERAGGYWVLKEKYRAGLNPQEKVKLEKEPMALFMEGGIQDLARVPMEQIDAAKLTKDDVDVRLKWLGLFHRRKHQYGRFMMRLKLPNGVTTSEQTRYLASVIEAYGADGCADVTTRQNWQIRGVTLPDVPAILDGLRAVGLTSLQSGMDNVRNPVGNPLAGVDPHEIVDTRPYTNLLSSYVTNNSQGNPTITNLPRKWNVCVIGSHDLYEHPHINDLAYMPAVKDGEFGFNLLVGGFISPKRWAEALPLDAWVAGDDVVPVCKAILEAYRDLGSRGNRQKTRMMWLIDELGMEVFRSEVEKRMPNGVLERAAPEDLVDKRWERRDYLGVHPQKQEGLSYVGLHVPVGRLQAADMFELARLADEYGTGELRLTVEQNIVLPNVSNERLDALLAEPLLQEQRLSPRPSMLLRGLVACTGNQFCGQAIIETKARALQVAREVEKRVAVPRPVRMHWTGCPNSCGQVQVADIGFMGCLTKDSDGKIVEAADIFVGGRVGSDSHLADVYRKSVPCKDLVPIVADLLVERFGAVPREREEDEE
What are the official names of this protein?
Ferredoxin--nitrite reductase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSGA_PROM1
Sequence: MNKNKSNKLKGIVVALKANFLIVEIDHKNFKDYSFDEFNGKIRLLCIRRSKLNYQGLFIDVGDIVGVESIDYKNKRAVVSDVEPRQSFLKRPAVANVTLVSICISADEPLFDMEQTSRFLLTAECANIEPLIILTKIDLITKNDLILYINKFKSWGYDCIPVSIHNSQGIDSLIERLRKTKLTVLAGPSGVGKTSLINHLIPTVSLPTSSVSKKLKRGTHTTRHVELFAIGNGSLLADTPGFNRPEIVCEPSDFAFLFPEFRTQLSNSQCKFRNCLHRDEPGCVIDKDLERYPFYRENLEEMINSPLPYQAG
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB2_ENCCU
Sequence: MITKTGTTIVGMKYKTGVILAADTRSTQGPVVSDKNCVKIHQITDKIMCCGAGTAADASRVARMASRELRLFQNKYLRLPLVSHFRKVCTQHLHKYGGGIGAALIVGGIDSEGCHLYEIHPHGSENSALFVSLGSGSLGAIATLESRYRAMDKDEAIDLACDAVKAGILNDLYSGSNIDVCVIDYSGVEFLRNYRRIGVSENTDTLVYPLDSVRIKREEVFDIVEEY
What is the function of this protein?
The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  It has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Probable proteasome subunit beta type-2, 26S proteasome beta-type subunit PUP1, Multicatalytic endopeptidase complex subunit PUP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EFTS_FLAPJ
Sequence: MATITAADVNKLRTITGAGMMDCKKALVESDGDFDLAIENLRKKGQKVAANRSDRESTEGAAIAVVNADNTVGVVITLNCETDFVGMNENFVKMAVEMANLALNFNNKEEFLASDFNGITIADKLIEQTGVIGEKLEIRTFEKLEGAFVGSYIHSGNKIATLTAFSAKADGIEEAARNVAMQAAAMNPIALNEEGVDADTIAKEIEIAKDMLRAEGKPEAMIENIAKGKLGRFFKDNTLVNQDYIKDSSMSVANYVKSIDANLIVTGFKRAALG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_CYAP4
Sequence: MISSNDFRPGVSIEWNNGVWRVVEFLHVKPGKGSAFVRTKLKNVQNGNVVEQTFRAGEMVPQANLEKSLMQHTYKEGDQYVFMDMETYEEARLTAAQIGDRVKYLKEGMEASVIRWGEQVMEVELPNSVVLEVVQTDPGVKGDTATGGTKPAIVETGAQVMVPLFITVGERIKIDTRNDSYLGRE
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK16_CHLAT
Sequence: MLSPRRTKFRKHHRGRMKGLAARGNQISFGDFALRALEPAWITSRQIESGRRAMTRYAKRGGKIWIRIFPDKPVTMRPAETRMGSGKGSPEYWVAVVKPGKILYEMKGVSETVARAAMRIASYKMPIKTQFITRIETKAPIVE
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUSB_HAMD5
Sequence: MNPSARRRARECVVQALYAWQVSQNDIAEVELSFLADQETQGADIAYFRHVLLGVASDVEALDTLMTPYLSRQFQELGQIEKAILRLAMFELNKRDDVPYKVTINEAIELGKTFGADDSHKFINGVLDKAAPIIRKRMQIRSQNGPYQSVC
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NUOI_AGRVS
Sequence: MASVSQAVRSLFLKEFVNAFFLSMRYFFKQKATVNYPFEKGPVSPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIEAGPRRNDGTRRTVRYDIDMVKCIYCGFCQEACPVDAIVEGPNFEFSTESREELYFDKAKLLANGDRWEREIARNLAQDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARNT_EDWI9
Sequence: MKKIAGWFTLAVLFVLYYIVPLPGRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPVAGYWVNNLGQWLFGDGNFAVRFGAVLATVLSALLVFWLARRLLSGPRPAVVAVLIYLTSFLVYGVGSYAVLDPIFTLWMTAAMCSFWLGEQASSARGKAGGYILLGLACGMGFMTKGFLALAIPVIAVLPWVIAQRRWKSLFCFGPLAVLSAILISLPWVLAIAQHEPDYWRYFFWVEHIQRFAEDNAQHKAPFWYYLPILLIGLLPWLGLLPGALREGWRGRVSQGGDFYLLGWAVMPFLLFSIAKGKLPTYILPCFAPLAILMAGYVQRLTGENGKALRINGLINLLVGLGGMAAILLVLAPWGITGHPLFGAHEIGKVILGTIAFGVWALFGALSLYHSRRYWRWSAACLLGVALLIGTALPQQVMESKQPQALIQAAMPQLQASRYILSDSVGVAAGLAWELKRSDIYMYDKTGELQYGLSYPDAAGHLVKAEQFPAWLAEHRKQGAISLVLLLPRDGQINPALPSADMTLRKGRFLLLQYQQQP
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1271_STAEQ
Sequence: MTKIKEIKKVLQQEDADAAWITTPLNIFYFTGYRSEPHERLFALLIPSNEEPVLFCPKMEVEEVKQSPFKGKIIGYLDTENPFDKYSKTFSKMLIESEHLTVKRQRELTKAFNIEHYQDVDQSIKDLRNIKSEDEIINIKKAAALADKCIEIGKSFLKEGVEEREVVNHIENEIKKYGVNEMSFDTMVLFGDHAASPHGTPGDRKLQQNEFVLFDLGVVYHHYCSDMTRTIHFGTPNKEAQNIYNIVLKAETEAIKSIKPGVTIKDIDKIARDIIEEAGYGDYFPHRLGHGLGLEEHEYQDISSVNNNQLEAGMVITIEPGIYVPHVAGVRIEDDILVTENGYEILTQYEK
What are the official names of this protein?
Uncharacterized peptidase SERP1271.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: RL31_SALNS
Sequence: MKKGIHPNYVEITATCSCGNVIKTHSTVGHDLNLDVCGKCHPFFTGKQRVVDTGGRVERFNKRFSIPGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: KLC4_BOVIN
Sequence: MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALHSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALANHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHAAEEKEGDASKDSLDDLFPNEEEEDPSNGLSRGQGAQHSGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPVVATMLNILALVYRGQNKYKEAALLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKIRHREGSTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRSRKQGTDPISQTKVAELLGEGDSGRTSQEGLGGSVKFEGGEDASVAVEWSGDGSGALQRSGSLGKIRDVLRRSSELLVRKLQGSEPRPSSSNMKRAASLNYLNQPSAAPLQVSRGLSASSMDLSSSS
What is the function of this protein?
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.  The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity).
What are the official names of this protein?
Kinesin light chain 4, KLC 4, Kinesin-like protein 8.
What is the protein family that this protein belongs to?
Belongs to the kinesin light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: UPPS_MICLU
Sequence: MFPIKKRKAIKNNNINAAQIPKHIAIIMDGNGRWAKQKKMPRIKGHYEGMQTVKKITRYASDLGVKYLTLYAFSTENWSRPKDEVNYLMKLPGDFLNTFLPELIEKNVKVETIGFIDDLPDHTKKAVLEAKEKTKHNTGLTLVFALNYGGRKEIISAVQLIAERYKSGEISLDEISETHFNEYLFTANMPDPELLIRTSGEERLSNFLIWQCSYSEFVFIDEFWPDFNEESLAQCISIYQNRHRRFGGL
What is the function of this protein?
Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate.  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: IF13_BURO1
Sequence: MAKEELLELDGVVDEVLPDSRFRVTLENGAVVAAYASGRMRKHRIRILAGDRVKLELSVYDLTKGCINFRHKDERASPGVPRNRFVRR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 3.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
Protein: CO8A1_CHICK
Sequence: MAVQPGPPQLLQVLLTISLGSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLTMGKEMPHAQYGKEYPHLPQYMKEVQPVPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGQGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGPKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGAKGDRGPKGPPGPPGLQGPKGEKGFGMPGLPGLKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGPPGEPGPQGPIGVPGVQGPPGLPGVGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGVGKPGFPGPKGDRGIGGVPGALGPRGEKGPVGAPGMGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGIRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGITGPSGPIGPPGIPGPKGEPGLPGPPGFPGVGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPAPQGEYLPDMGLGIDGVKTPHAYAAKKGKNGGPAYEMPAFTAELTAPFPPVGAPIKFDRLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQNPSEQAAGLYAGQYVHSSFSGYLLYPM
What is the function of this protein?
Macromolecular component of the subendothelium.  Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells.  Also a component of the endothelia of blood vessels.  Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity).
What are the official names of this protein?
Collagen alpha-1(VIII) chain.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: THIM_CORGL
Sequence: MANSFLDSLTLVRQNTPLVQCLTNSVVMQFTANVLLAAGATPAMVDTPAESAEFAAVANGVLINAGTPSAEQYQGMTKAIEGARKAGTPWVLDPVAVGGLSERTKYAEGIVDKQPAAIRGNASEVVALAGLGAGGRGVDATDSVEVALEAAQLLAKRTGGVVAVSGAEDLIVSADRVTWLRSGDPMLQLVIGTGCSLGALTAAYLGATVDSDISAHDAVLAAHAHVGAAGQIAAQKASAPGSFAVAFIDALYDVDAQAVASLVDVREA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: SIGE_MYCTE
Sequence: MELLGGPRVGNTESQLCVADGDDLPTYCSANSEDLNITTITTLSPTSMSHPQQVRDDQWVEPSDQLQGTAVFDATGDKATMPSWDELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGTFEGWLHRITTNLFLDMVRRRARIRMEALPEDYDRVPADEPNPEQIYHDARLGPDLQAALASLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLAAHPEHGECAVHVNPVR
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released.  Responds to surface stress (H(2)O(2)) (By similarity).
What are the official names of this protein?
ECF RNA polymerase sigma factor SigE, ECF sigma factor SigE, Alternative RNA polymerase sigma factor SigE, RNA polymerase sigma-E factor, Sigma-E factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: AGRL3_MOUSE
Sequence: MWPPQLLILTMLLAPVVHGGKHNERHPALAAPLRHAERSPGGALPPRHLLQQPAAERSTAHRGQGPRGAARGVRGPGAPGAQIAAQAFSRAPIPMAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYKVEQKVFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSELERPPVRGISTTGSLGMGSTTTSTTLRTTTWNIGRSTTASLPGRRNRSTSTPSPAVEVLDDVTTHLPSAASQIPAMEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREGLLNNARDTSVMDTLPLNGNHGNSYSIAGGEYLSNCVQIIDRGYNHNETALEKKILKELTSNYIPSYLNNHERSSEQNRNMMNKLVNNLGSGSEDDAIVLDDAASFNHEESLGLELIHEESDAPLLPPRVYSTDNHQPHHYSRRRFPQDHSESFFPLLTDEHTEDLQSPHRDSLYTSMPALAGVPAADSVTTSTQTEAAAAKGGDAEDVYYKSMPNLGSRNHVHPLHAYYQLGRGSSDGFIVPPNKDGASPEGTSKGPAHLVTSL
What is the function of this protein?
Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells (PubMed:22405201, PubMed:25728924, PubMed:26235031).  Plays a role in the development of glutamatergic synapses in the cortex (PubMed:22405201, PubMed:24739570).  Important in determining the connectivity rates between the principal neurons in the cortex (PubMed:24739570).
What are the official names of this protein?
Adhesion G protein-coupled receptor L3, Latrophilin-3, Lectomedin-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell junction.
Protein: RL5B_XENLA
Sequence: MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNKFGLDKVYEGQVEVTGDEYNVESVDGEPGAFTCYLDAGLTRTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNPEVHRKHIFAQNIAEYMRLLMEEDEDAYKKQFSQYIKNGVAADQLEDIYKKAHAGIRENPVHEKKPKKEVKKKRWNRAKLSLEQKKDRVAQKKASFLRAQEKADS
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs.  It also couples ribosome biogenesis to p53/TP53 activation.  As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53.
What are the official names of this protein?
60S ribosomal protein L5-B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: DMD5_CAEEL
Sequence: MPVSPSSVSVLPPTSLEQILRIRAERNQRTPKCARCRNHGTTSALKGHKRYCQWKDCMCAKCTLIAERQRVMAAQVALRRQQSQEERDARDLEVLLGSAGNANDLLDILRLDAGEHHGKNHASPTTNNNNNTEEKYEDSQGQRSSPSSPTGSETVVSTSSPPELSSESTPNTSGSVIPTSPVFKPNGYSSMPMFNPVYGRPFMRFPMFSVMPHFFGTPSMSDFASAASLAAPPAFFSAQPTIATSSPSTIFPQTAPLDYSHRLMKNEEAEEEYRENDKTF
What is the function of this protein?
Transcription factor (By similarity).  Required for sex-specific synaptic pruning, probably acting downstream of sex-determining transformer protein tra-1 (PubMed:27144354).
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor dmd-5.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UD2B9_MACFA
Sequence: MSVKWTSVILLIQLSFYFSSGSCGKVLVWAAEYSHWMNMKTILEELVQRGHEVTVLASSASILFDPNNSSALKIEVFPTSLTKTEFENISMQEVKRWIELPKDTFWLYFSQMQEIMWRFGDIIRNFCKDVVSNKKLMKKLQESRFDVVFADPIFPCSELLAELFNIPLVYSLRFTPGYIFEKHCGGFLFPPSYVPVVMSELSDQMTFMERVKNMIYMLSFDFYFQMYDMKKWDQFYSEVLGRPTTLSETMGKADIWLIRNSWNFQFPHPLLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVTNMEEERANVIASALAQIPQKVLWRFDGKKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGVPMVGIPLFADQPDNIAHMKTKGAAVRLDFDTMSSTDLANRLKTVINDPLYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWFQYHSLDVIGFLLACVATVIFVIMKCCLFCFWKFARKGKKGKSD
What is the function of this protein?
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.  This isozyme is active on C18, C19, and C21 steroids, bile acids, and several xenobiotics including eugenol, 1-naphthol, and p-nitrophenol.
What are the official names of this protein?
UDP-glucuronosyltransferase 2B9, UDPGT 2B9.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PLGT2_MOUSE
Sequence: MFSISLLSCLFLGTVPALAQTGGERRLSPEKSEIWGPGLKAHVVLPARYFYIRAVDTSGEQFTSSPGEKVFQVKISAPDEQFTRVGVQVLDRKDGSFIVRYRMYASYRNLKIEVKHHGQHVAESPYVLRGPVYHENCDCPLEDSAAWLREMNCSETISQIQKDLAHFPTVDPEKIAAEIPKRFGQRQSLCHYTLKDNKVYIKTHGEHVGFRIFMDAILLSLTRKVRMPDVEFFVNLGDWPLEKKKSNSNIQPIFSWCGSTESRDIVMPTYDLTDSVLETMGRVSLDMMSVQANTGPPWESKNSTAVWRGRDSRKERLELVKLSRKHPELIDAAFTNFFFFKHDESLYGPIVKHISFFDFFKHKYQINIDGTVAAYRLPYLLVGDSVVLKQDSIYYEHFYNELQPWKHYIPVKSNLSDLLEKLKWAKEHDAEAKKIAKAGQEFARNNLMGDDIFCYYFKLFQGYANLQVSEPQIREGMKRVEPQSEDDLFPCTCHRRKAKDEL
What is the function of this protein?
Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C.  Can also catalyze the transfer of xylose from UDP-xylose but less efficiently.  Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1.  May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway.
What are the official names of this protein?
Protein O-glucosyltransferase 2, Endoplasmic reticulum resident protein 58, ER protein 58, ERp58, KDEL motif-containing protein 1, Protein O-xylosyltransferase POGLUT2.
What is the protein family that this protein belongs to?
Belongs to the KDELC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: AZOR_CLOBB
Sequence: MKKLLYITVNSKPEELSASKTVGRAFVNRFLEKHSDFEIEELDLYKCHIPRLEYEYFEKRSCLVNEDAFNKLDKKQQEEVHKIVKLTDQFKEADVYVIAAPMWSMSFPAPLKEYIDCIVMDGKTVDIKDGEKPEGLLNDKPRGAVYIQSSGAKMNVLLKVVMDKGVHYIESIMKFMGIEKFEELLVDGTGTTEEEKNKAIEKAFEKIDSVIDGIW
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RL31B_BURCM
Sequence: MKEGIHPNYREVVFQDMSNGFKFITRSTIQTRENIELDGKTYPLAKIEVSSESHSFYTGQQKIMDTAGRVEKFKNKFGARASGKLAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.