PharMolix/UniProtQA huggingface dataset:
Protein: TAT_HV1S3
Sequence: MEPVDPNLEPWKHPGSQPRTACTNCYCKKCCFHCQVCFITKGLGISYGRKKRRQRQRAPDSSQNHQDSLSKQPSSQPRGDPTGPKESKKEVERETETDPLD
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: NRDR_PSYA2
Sequence: MHCPYCNASDTKVIDSRLAAEGAQVRRRRSCNSCQERFTTFEVVEVVMPRIIKSSGKIEPYDNDKLRRSILLPLQKRPITIDEQEAMISRIEKRVRQMGEREVSSKVLGEIIMSELKTLDDVAYVRFASVYRDFQDIDAFHQEIANIRPNDK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PXPA_SALEP
Sequence: MNIDLNADVGEGCASDSELLTLVSSANIACGFHAGDAQTMLTSVREALKNGVAIGAHPSFPDRDNFGRTAMALPPETVYAQTLYQIGALGAIVQAQGSVMRHVKPHGMLYNQAAKDPHLAQAIAKAVHDYDPSLILVGLAGSELIRAGERHRLVTRQEVFADRGYQADGSLVPRMQPGALIHDEEQALAQTLDMVQAGRVKSVTGVWTTVTAQTVCIHGDGEYALAFARRLRAAFNARNIHVIA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: COXM1_BOVIN
Sequence: MALDPSEQHLRHVEKDVLIPKIMREKARERCSEQVQDFTKCCKDSGVLMVVKCRKENSALKDCLTSYYKDPAFYEECKMEYLKEREEFRRTGIPTKKRLQKLPTSM
What is the function of this protein?
Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.
What are the official names of this protein?
COX assembly mitochondrial protein homolog, Cmc1p.
What is the protein family that this protein belongs to?
Belongs to the CMC family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Colocalizes with MT-CO1.
Protein: FEN1_NAEGR
Sequence: MGIKGLSQLILDEAKDSVKEDQLKNYFGRKVAIDASMAMYQFLIALKNTGMDLTDKDGEVTNHLQGLLARTTKMLEYGIKPCYVFDGKPPQLKSGELEKRKERQKEAMEQFALAQEEGDEEKMVMWNKRTTRMTKEQSNDGKKLLRLMGVPVVEAPGEAEAQCAELCKGGLVYATATEDMDALTYATPVLARHLTFSEARKQPIQEFTFKQVIEGLGVTVDQFIDICILCGCDYTDSIKGIGPKKALAMIKKYGNIENLLKNIEGKHYQAPSEFPYEEVRNIFKNPDVTPSSELVDTMKWTEPDEEGLIEFLVKEKQFDEERVRGYIKRIKSSRGKPTQTRLDGFFTPVASSSTTKKKAPAKKDDKKSATDKKRKAADASTSSKKKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: FABH_HAES1
Sequence: MYSRILATGSYIPANIRTNADLEKMVETSDEWITTRSGIKERRIAGENETVATMGFKAAKNALQLANICPNDIDLVLVATTSHSYAYPSAACQIQGMLDIDDAISFDLAAACTGFIYALSVADQFIKTGKVKKALVIGADINSRKLDETDRSTVILFGDGAGAVILESSDIEGIISTHLHASLDKSNALILPQTQHGEAQSGYIQMQGNATFKLAVRELSNVVEETLRDNHLDKADLDWLVPHQANLRIITATAEKLNMSLDQVVITLDKYGNTSAATVPVALDEAVRDGRIKRGQLLLLEAFGGGWTWGSALVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_RHIWR
Sequence: MKVKVQTLDAKASGDIELNDEVFAVEPRADILARVVQWQLHNRRAPARAARERSDVARTGKKFGRQKGGGTARHGDRRAPVFIGGGKAHGPRARVFESSLNKKVRALGLKMALSSKAKDGKLVVVDTLELKDAKTKALIAKIGKLGFGATALVIDGEAVDNGFQLASSNIHTINVLPAIGANVYDILKHETLVLTRAAVEKLEARFNG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: MIAA_STRA3
Sequence: MRKIKLIAVVGPTAVGKTALGIELAKTFNGEIISGDSQQVYQKLDIGTAKASKEEQEQAYHHLIDVREVNENYSVYDFVKEAKVAIDTIISKGKIPIIVGGTGLYLQSLFEGYHLGGEVNQETLKAYREKLESLSDEDLFEKLTEQSIVIPQVNRRRAIRALELAKFGNDLQNSESPYDVLLIGLNDDRQVLYDRINRRVDLMIDNGLLDEAKWLYDNYPSVQASRGIGYKELFPYFSKQIPLEEAVDKLKQNTRRFAKRQLTWFRNRMNVEFIMVGEENYQQKIKRKVSDFLSSK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GATB_METKA
Sequence: MADVKIGFEVHVQLDTRTKLFCDCPTDYEDAEPNENTCPVCTGMPGAKPLPPNEEALLIALEIAHMLDCEPVLDRPLYFQRKHYDYPDLPSGYQRTSVPIAVNGELDGVRIREIHVEEDPGRWEPSTGRVDYNRSGVPLIEIVTEPDMRSPEEARDFLRRLMQVLRYSGKVKGDGGIRVDANVSVEGGARVEIKNINSIKGVYRALRFEIQRQLNLMKHGREVRRETRAFREDQGTTVAMRSKETAEDYRYIPDPDIPVFEITEDLWEKAVARAPEPPHHRARRMAEEYGISLEAAEALVTEREWADFFEEVVEKAPDDWDIEFIDQWVRKEIKKILNKKEMTFREAKITPEEFIELLELVREDKITRQNALNALWEAVDSDKSPVEIIEENGLLKVSDEDRLARVVEEVIEENPQAVEDYKSGKEEAIHYLMGQVMRKTRGQADPEVTMRLLRERLDSDG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PLSY_COXB2
Sequence: MAFIISIIIAYLLGSLSFAVIVAKLMKLPDPRTTGSGNAGATNMLRVGGRQAAFYVLLGDAAKGLIAVLIARFLNVQGVSLAFVGLVAVLGHLFPVYFKFRGGKGVATMMGVLLGLSFWIALFVIATWVIVVSIFRYSSVAALVSAVAAPIYTIIAGRTDYLFPVLIIAILLIWKHWENFQRLRKGTEDKVKL
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSBP_DANRE
Sequence: MLRNASAQILKQFVRHRTTDASLTLEKSINKVQILGRVGQDPVMRQVEGRNPVTIFSMATNEMWRSGEGEPVGAGDVTQKTTWHRISVFKPGLRDVAYQYVKKGSRIFVEGKLDYGEYVDKNNVRRQATTIIADNIVFLSENLRDQ
What is the function of this protein?
Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA) (By similarity).  May be required to maintain the copy number of mitochondrial DNA (mtDNA) and play a crucial role during mtDNA replication (PubMed:31550240).  Required for retinal ganglion cell differentiation and retinal integrity (PubMed:31298765).
What are the official names of this protein?
Single-stranded DNA-binding protein, mitochondrial, Mt-SSB, MtSSB.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Protein: Y265_BORBU
Sequence: MFIVFYLILIIFIFIYFHVYINLKIKSNSILRKFKSEVDKTIIEINQATDRNINIIEIKIESLNRIIKEVDERIEILDQRLLGFNNSSIPGNSPSSFGSKSDGIYKSNLDYSMPTIEKNIIKESYNVRNQIILLHEQGMSFEAIAKKFKLDLGEVELIISIHRGGVHEKMDRY
What are the official names of this protein?
Uncharacterized protein BB_0265.
What is the protein family that this protein belongs to?
To T.pallidum TP0711.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ERA_NEIMA
Sequence: MDIETFLAGERAADGYRCGFVAIVGRPNVGKSTLMNHLIGQKISITSKKAQTTRNRVTGIYTDDTAQFVFVDTPGFQTDHRNALNDRLNQNVTEALGGVDVVVFVVEAMRFTDADRVVLKQLPKHTPVILVVNKIDKDKAKDRYALEAFVAQVRAEFEFAAAEAVSAKHGLRIANLLELIKPYLPESVPMYPEDMVTDKSARFLAMEIVREKLFRYLGEELPYAMNVEVEQFEEEDGLNRIYIAVLVDKESQKAILIGKGGERLKKISTEARLDMEKLFDTKVFLKVWVKVKSGWADDIRFLRELGL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: ARSC2_CORGK
Sequence: MKSVLFVCVGNGGKSQMAAALAQKYASDSVEIHSAGTKPAQGLNQLSVESIAEVGADMSQGIPKAIDPELLRTVDRVVILGDDAQVDMPESAQGALERWSIEEPDAQGMERMRIVRDQIDNRVQALLAG
What is the function of this protein?
Involved in defense against toxic arsenate.  Involved in the mycothiol/myoredoxin redox pathway which uses a mycothioltransferase mechanism; facilitates adduct formation between arsenate and mycothiol (By similarity).
What are the official names of this protein?
Arsenate-mycothiol transferase ArsC2, Mycothiol-dependent arsenate reductase ArsC2.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARID1_CAEEL
Sequence: MSDDPAFLALGTEVSAKFKGAYCEAKIQKVDRSLKVKVSLKESPFGQMIVQDNDLPNAKFEINELTDVVFQRKFIRCQIQSIKDQSKYHVVFNDGDEKELRRTQLVLKGGKHFAADGNLDSMPLTNPESFSTPVIRGAAKRGAQKIRNAISEASGSRGGAVLLHNDDDENDEEDQEDGENEEDADDDDDDTEEQQQPRERRRAAAISAIGVLKKAIEDTQSEESSADSSEERERARSRRKRKDEASSAVTSDEEDQEDLATTDSENPVINGASSAAALSKTLQRKLEKQAMKREKQRLKEEEREEKLRLKEENREKKRREKARIMELKRLEKVYRTSNARIQENHEKSMTQIISHRSVRYFARFSDLKHRRKKKKLYLHEHRQKVNSRIRNVKLYFAWRFVAHKARLSYFARYALQWWRTSEDQAYSLIRTEKLLRSQRRRDWVGSWLEGLEREKIRFVVIHESYTQARRILKYIERGTEKRTFAERCDIEYEDIESSTVSSHFRDQEWFPAVLFPQVFSDENGSEGRQRIVRHMGNGQLVQVWEDDLVPFDWLPEYSFADVTAMTEKKPVEMRRKFKLAWRFATDYAQNRLDARSIRSILEWKFIRPSSRRLKITPIPVQAPSPNRCGEDHDDLVSTPNESDYDSDATIKNVDAETKDLFVAMLVQFHDAHNSVIDTNPTIQGHEVDLYYLYELAKKTGGPKKVYAANLWSDYAKKLVPAATDAEEELKTIFKNFLESYLAINTKLSWPMESLQPRTERKVVLPGQYSESRKKRTQAIMSQVQTPPTAPGSSKKGRVGSGGTRGRKRKVSSESVQLKKRNRKSSSRATTASPGPSEDRFSFQRPQDSDDVTDVPDDMTDHEDLLPEAATRKKYERKSQTPGRRSLSSRRDDTTPVSSMAAAPPKKGRPRKNTTVTTPVLSVPKSEGRGPRKEDTTTKFVRANVLSHILSGQKLRAFYGDEWFRANAIEDATDCTDEIMDIMLAHQDFFTPDTPRLSPSAIQDLDKVLKKIRAKTHYTGWNQRYDEFMKLEKLMVTVEDQMIARGRFRHLPRGRELKAETLALVEKHFRADDEDDGVPKTLAFYLKIAQEALSLSEKRAVADDDESSDSDTDFEQKPDTSAAAAVNGGKSESEEEEEEKTVVMGGDEEAEEEVKSEDVLVESVDQESPPTTSQGTTTPETAATGGLESESDEPEYPPVPEELVPPPPVLLENFPSTDRFSSGGSSNYPTLSRQGSINSMASPMFSPNSDLSLSGPLTLPRSGPLTMANIRQSPTPDEVVGSLRKRLSQTSESSESSELPPPPSAASKSKRIRRASERSIDSASEHHRMMRSPRILTTQHSSGALIFDISTTQPTDTSGPIEALSVRKPGRRKTVFAASPTLLTSGPLTLSSSAPPPPPASPAPPQHAQKTLGRPRKTPSTSSRKPEEEDEAEQIPTTVVGVTEEASVADSSAKEDLTSEDGSATPQDEKDDSESTTTTDTITPKSIRGGKRRRGGGRFGGSYPVKPAKPGRKPKDPHAEEGADEKDPEDQTPTTMTTSTPTRADSFQTQKNRMAKLMEGKPHDYSFLDLPDFDKIIEEAPKEDINILMEERTYELREIFAQCKADLSALEKRYRQQNEAKRKAEFAAKTASSAAAAQASSSTCSTPRP
What is the function of this protein?
DNA-binding protein which modulates activity of several transcription factors (By similarity).  Plays a role in the modulation of endoplasmic reticulum (ER) homeostasis during chemical and pathogen stress, including exposure to the Gram-negative bacterium P. aeruginosa (PubMed:30287474).
What are the official names of this protein?
AT-rich interactive domain-containing protein arid-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: IGSF5_RAT
Sequence: MEGSWRDVLAVLVILAQLTVSGSSYQIIEGPRNVTALKGSEARFNCTVTHGWKLIMWALNGIVELSLTSQKPIITSNRFTSASYNSTDSFISEMIIHNVQLNDSGPVQCSLQNSNVFGFAFLSVQVMGTLNIPSSNLIVTEGEPCNVTCYAVGWTPLPNISWELEVPVSHSSYYSFLEPGNSLRVLSVLDLTPLGNGTLTCVAEMKDLQASESLTVNLTVVQPPPDSIGGEGQALPTWAIILLAVAFSLLLILIIALIIIFCCCCVSRREKEESTYQNEIRKSANVRTGKADPETWLKSGKENYGYKSDEARAAQIASLPPKSGEVSLPEQRSSLPQQELDKHRPSPVTHPRVSFDIASPQKIRNVTIV
What is the function of this protein?
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells.  Mediates calcium-independent homophilic cell adhesion.  In testis, it may function as a cell adhesion molecule rather than a tight-junction protein.  It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity).
What are the official names of this protein?
Immunoglobulin superfamily member 5, IgSF5, Junctional adhesion molecule 4, JAM-4.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=In podocytes, it is mainly found in the apical plasma membrane where no junctional structure is seen. The subcellular location is altered in puromycin amino-nucleoside nephropathy (PAN). A cytoplasmic localization has been observed which may indicate the existence of variants lacking a signal sequence (PubMed:16118391). May be primarily targeted to apical membranes and subsequently recruited to tight-junctions (PubMed:12940823).
Protein: RS8_XYLFA
Sequence: MSMTDPIADMLVRINNAASVGKPNVRFPFSRVKLAIALVLKHEGYIFDAKVIQGDNSKSDIEIVLKYFEGRPVIRILKRVSRSGLRKYCGKAELPKVLGGLGISIISTSKGIMIDSKARESGVGGEVLCFVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ACCD_PSEA7
Sequence: MSNWLVDKLIPSIMRSESQKSSVPEGLWHKCPSCEAVLYRPELEKTLDVCPKCDHHMRINARTRLDIFLDEEGREELGADLEPVDRLKFRDSKKYKDRLSAAQKDTGEKDALIAMSGKLEGMPVVACAFEFSFMGGSMGAIVGERFVRAANVALEQRCPLICFSASGGARMQEALISLMQMAKTSAVLARLREEGIPFVSVLTDPVYGGVSASLAMLGDVIVGEPKALIGFAGPRVIEQTVREKLPEGFQRSEFLLEHGAIDMIVHRGELRPRLARLLSAFTHSPSPVSA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNE_MYCS2
Sequence: MAEDAHTEDLSTQTPQQEGLPERLRVHSLARVLGTTSRRVLDALAEFDGRQRSAHSTVDKADAERVRAALTESPAAETPPEEAPAAETPVADLVVVQAEQVEVVTVSEAGPAEPAEPAEPEAPAAEAEAEAETEVADEAETPEPTFRGAVLVGDEPESRLILEHANIPPARETQTERPDYLPLFVAPQPVSFEPAVVDDEDEDDDTETGAESDFDSGADSDSDDDQADRPRRRRRGRRGRGRGRGEQNDDATSDADTDSTEDQTDGDEQESGEDSDDSGDEDSTTTEGGTRRRRRRRRRKSGSGDSDDAVSPDDPPNTVVHERAPRTERSDKSDDSEIQGISGSTRLEAKRQRRRDGRDAGRRRPPILSEAEFLARREAVERTMIVRDKVRTEPPHEGARYTQIAVLEDGVVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWEAAGLGGQNRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGVKEEDIRSDVERLQKRWSEIEAKAAEVTEKKAGAAVALYEEPDVLVKVIRDLFNEDFSSLIVSGDEAWNTINSYVEAVAPDLMPRLTKYEPAGPDAPDVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSGGNLEQTVTRNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTACTHCGGRGIVLHGDPIDSASSNGGRKSDSSGGGGSGGGRRGKRGKKGAARTEEVHVAKVPDHTPGEHPMFKAMAAANGKHEGDEDHEDHEDHETAEDTTAAEVRDDTRDEHDADERAHVVTAAVGAAGDEDLDDSDEDSDLDSDEESDDESDEDEIELDDDEDELDEDIEVIGDSDDSDDSDDSDEDDDSDDSDDDSDEDEDSDSDEDEEPVREVYEPPVTAPRARVRRRAAARPAGPPSHD
What is the function of this protein?
Endoribonuclease that plays a central role in RNA processing and decay.  Plays a major role in pre-16S rRNA maturation, probably generating the mature 5'-end, and a minor role in pre-5S and pre-23S rRNA maturation (PubMed:22014150).  Probably also processes tRNA (By similarity).
What are the official names of this protein?
Ribonuclease E, RNase E.
What is the protein family that this protein belongs to?
Belongs to the RNase E/G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAMP_NOMGA
Sequence: MKTQRDSPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCVGTVILNQARDSFDISCDKDNRRFALPGNFFRKAREKIGKEFKRIVQRIKDFLQHLVPRTEA
What is the function of this protein?
Exhibits antimicrobial activity against E. coli and B. megaterium (in vitro).
What are the official names of this protein?
Cathelicidin antimicrobial peptide.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TOM72_ARATH
Sequence: MAAKSTLKIKGKAKPSKGSSSSSSSSASSKYKVFKDWTNWSLQKAKVATHYGFIPLIIIIGMNSDPKPHLFHLLSPV
What is the function of this protein?
Seems to act as a modulator of the dynamics of the mitochondrial protein transport machinery.  Seems to promote the dissociation of subunits of the outer membrane translocase (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM7-2, Translocase of outer membrane 7 kDa subunit 2.
What is the protein family that this protein belongs to?
Belongs to the Tom7 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: PGLR2_ASPNA
Sequence: MHSFASLLAYGLVAGATFASASPIEARDSCTFTTAAAAKAGKAKCSTITLNNIEVPAGTTLDLTGLTSGTKVIFEGTTTFQYEEWAGPLISMSGEHITVTGASGHLINCDGARWWDGKGTSGKKKPKFFYAHGLDSSSITGLNIKNTPLMAFSVQANDITFTDVTINNADGDTQGGHNTDAFDVGNSVGVNIIKPWVHNQDDCLAVNSGENIWFTGGTCIGGHGLSIGSVGDRSNNVVKNVTIEHSTVSNSENAVRIKTISGATGSVSEITYSNIVMSGISDYGVVIQQDYEDGKPTGKPTNGVTIQDVKLESVTGSVDSGATEIYLLCGSGSCSDWTWDDVKVTGGKKSTACKNFPSVASC
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase II, EPG-II, Pectinase 2, Polygalacturonase II, PG-II, Polygalacturonase X2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZFYV1_MOUSE
Sequence: MSAQTSLAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKAGHVPYCDPCKGPNGHSPGVRQRAAVRCQTCKINLCLECQKRTHSGGNKRRHPITVYLVSKVQESLEGEEMDEETKRKKMTERVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPAQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEAPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGKEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDAFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNQCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDSCYDARNVQLDVTEAQADDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSVKLSKHHCRACGQGFCDECSHDCRAVPSRGWDHPVRVCFNCNKKPGDL
What is the function of this protein?
Plays a role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (PubMed:30970241).  Regulates the morphology, size and distribution of LDs (PubMed:31293035, PubMed:30970241).  Mediates the formation of endoplasmic reticulum-lipid droplets (ER-LD) contact sites by forming a complex with RAB18 and ZW10 (By similarity).  Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through FYVE-type zinc finger (By similarity).
What are the official names of this protein?
Zinc finger FYVE domain-containing protein 1.
What are the subcellular locations of this protein?
Golgi apparatus. Golgi apparatus, Golgi stack. Endoplasmic reticulum. Preautophagosomal structure. Lipid droplet. Mitochondrion. Note=Resides predominantly in the cisternal stacks of the Golgi. Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum. During starvation conditions, localizes to omegasomes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localizes to lipid droplets in the presence of oleic acid (By similarity).