PharMolix/UniProtQA huggingface dataset:
Protein: CSRA_PROMI
Sequence: MLILTRRVGETLMIGDDVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKTQPTDNY
What is the function of this protein?
Expression from a low-copy number plasmid has no effect on swimming, but blocks swarming and virulence factor expression as measured by cell lengthening and hemolysin, protease, urease and flagellin production (PubMed:12488561).  Expression destabilizes hemolysin mRNA (PubMed:12488561).  Complements an E. coli disruption mutant (PubMed:12488561).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_VIBVU
Sequence: MANNKSAKKRAIQAEKRRQHNASRRSMMRTYMKKTVAAIAAGDKEAATAAFAVVTPILDRMATKGLIHKNKAARHKSRFAAQIKAL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MURQ_SERP5
Sequence: MNLGALVSETRNPATMGLDEMSTLEMVSCFNQEDRKVPEAIEKVLPAIAQAVDLAAAALKAGGRLIYLGAGTSGRLGVLDASECPPTFGVPHGMVIGLIAGGPGALLKAVEGAEDDAALGEADLVALDLTATDMVVGLAASGRTPYVIGALRYARQLGCPTAAISCNPDSPIAHEVQVAISPVVGPEALTGSTRLKSGTAQKLVLNMLSTGAMVKLGKVYENLMVDVKATNVKLVDRACRIVVEATGAERSQAEAALTQTGFEVKPAILMILAGIDAQEAQQRLQQHDGYLRAALTR
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: UREF_RHILW
Sequence: MTGDRELQALLRLTAWLSPAFPVGSFAYSGGLERAVADGLVTDAVSLAAWIGTLIGYGSVWNDAVLLAESHRWQAEPARLFEIAALAEALAGSRERHQETMLLGDAFLTAARAWPDGVFERLPDKAAYPVAVGAVTGAHGIGPEKALAVFLHAYASQAVSSGIRLGVTGQRDGVAVLAGLEECITEVARRAAASTLDDLGSATVQADIAGLRHETQATRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_SHIDS
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: OBG_BEII9
Sequence: MKFLDQARIYIRSGDGGAGCLSFRHEKFIEFGGPDGGDGGRGGDVVALCVEGLNTLIDYRYQQHFKAKTGTHGMGKNRAGARGADCILKVPAGTQIFDEDGETLIADLTEIGQSVCLARGGNGGFGNAHFKTSTNQAPRRANPGQEGEEMTLWLRLKLIADAGLVGLPNAGKSTFLSTVSAARPKIADYPFTTLHPQLGVVAYGDREFVLADIPGLIEGAHEGVGLGDRFLGHVERCRVLLHLVDAGCEHAGKAYKTIRKELAAYGNGLDEKPEIVALSKIDTVDAETLKNQMARLKRAAKRTPLKLSAATHTNLTETLQSLLAAIDAAGAAQEAAAEPAATSWHPCD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_METPP
Sequence: MLNRKDQRLRRSKQTRVRIALQKVARLTVFRSNLHIYASVISDDGSKVLASASTAEKEVRARLGAAGKGGNTEAAALIGKRIAERAKAAGIESVAFDRGGFAYHGRVKALAEAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: DAPF_LIGS1
Sequence: MEMLKVHGSGNDFFILDEDNLEEPLTEEELIQLAQKVCDRDTGLHGGADGVLYVQAGHEGTDGRMRVINADGSEASMCGNGIRTVARYLSEKKNLAEFKIQTMHADLEVKKADKLAEKVPAFDAEISPVSFDAQDLLMHVGKEKLIDDYIPELSKAIKFSAVAVPNPHLIAFVDHETLMGEELGRIASYLNNGNNPIFPDGVNVSFVEILEPGKIFVRTFERGVGFTNACGTAMSASSLMYVLLHSDQIDFEKLITVINPGGMVRTMVHKRENGDYWMSLIGNATEVAKVNISQADAINGNFDNFTWNETGEQAAYEAFIAQLHR
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_PORG3
Sequence: MYRTNTCGELRLSHLQQTVTLCGWVQRVRRMGGMTFVDLRDRYGTTQLVFNRDSAPAELCDRAEDLGREWVIRATGTVMERSSKNPNIPTGDIEIAVGEMDVLNRSEVPPFTIEDETDGGDDLRMKYRYLDLRRHCVRSNMELRHRMALEVRKYLDGEGFLEVETPMLIKSTPEGARDFVVPSRMNPGQFYALPQSPQTFKQLLMVSGFDRYFQIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVLSTFEGMAKHLFRTIRHVEISEAFPRMTWHDAMKYYGSDKPDTRFDMRFVELMDVLKGHDFSVFDSAAYIGGICAKGAGSYTRKQLDALTDFVKRPQVGAKGMVYARVESDGSVKSSVDKFYTQETLQELRRTMEAEPGDLILILSGDDLMKTRKQLCELRLEVGSQLGLRDKNKFSCLWVVDFPLFEWDEETKRFYAMHHPFTSPKPEDIPLLDTDPGAVRANAYDMVINGVEVGGGSIRIHDSALQQKMFELLGFTPEKAQEQFGFLMNAFKYGAPPHGGLAYGLDRWVSLFAGLDSIRDCIAFPKNNAGRDVMIDAPSVIDEAQLQELFLELIPNEN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I86A2
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYVQMCTELKLNDHEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRKDGKWMRELILHDKEEIMRIWRQANNGEDATAGLTHMMIWHSNLNDTTYQRTRALVRAGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVREGRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEKEGYSLVGIDPFKLLQNSQIFSLIRPKENPAHKSQLVWMACHSAAFEDLRVLNFIRGTKVIPRGQLATRGVQIASNENMETIDSSTLELRSRYWAIRTRSGGNTSQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTERRTSDMRTEIIRMMENARSEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEFDS
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: KEFB_ECO27
Sequence: MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTHFSWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKIGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVLVAVKIFVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSSASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHTDTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCF2_COFAR
Sequence: MKGHQFKSWIFELREILREIKNSHYFLDSWTQFNSVGSFIHIFFHQERFIKLFDPRIWSILLSRNSQGSISNRYFTIKGVILFVVVVLIYRINNRNMVESKNLYLIGLLPIPMNSIGPKNDTLEESVGSSNINRLIVSLLSLPKGKKISESCFLNPKESTWVLPITKKCSIPESNWGSRWWRKWIGKGGDSSCKISNETAAGIEILFKEKDLKYLEFLFVYYMDDPTRKDRDWELFDRLSLRKRRNTINLNSGPLFEILVKHWISYLMSAFREKIPIEAEGFFKQQGAGSTIQSNDIEHVSHLFSRNKWAISLQNCAQFHMWQFRQDLFISWGKESDFLRNVSRENLIWLDNVWLVNKDRFFSKVRNVSSNIQYDSTRSSFVQVTDSSQLKGSSDQSRDHLDSISNEDSEYHTLINQREIQQLKERSILLDPSFLQTERTEIESDRFPKCLSGYSSMSRLFTEREKQMINHLLPEEIEEFLGNPTRSVRSFFSDRWSELHLGLNPTERSTRDQKLLKKQQDLSFVPSRRSENKEMVNIFKIITYLQNTVSIHPISSDPGCDMVPKDEPDMDSSNKISFLNKNPFFDLFHLFHARNRGGYTLHHDFELEERFQEMADLFTLSITEPDLVYHKGFAFSIDSYGLDQKQFLNEVFNSRDESKKKSLLVLPLIFYEENESFSRRIRKKWVRISCGNDLEDPQPKIVIFASNNIMGAVNQYRLIRNLIQIQSSTYGYIRNVLNRFFLMNRSDRNFEYGIQIQRDQIGKDTLNHRTIMKYTINQHLSNLKKSQKKWLDPLILISRTERSMNRDPDAYRYKGSNGSKNFQEHLEHFVSEQKSHFQVMFDRLRINQYSIDWSEVIDKKDLSKPLRFFLSKSLLFLSKLLFFLSNSLPFFCVSFGNIPIHRSEIYIYEFKGPDDQLCSQLLESIGLQIVHLKKLKPFLLDDHDTSQKSKFLINGGTISPFLFNKIPKWMVDSFHTRNNRRKSFDNTDSYFSMIFHDQDNWLNPVKPFHRSSLISSFYKANRLRFLNNPHHFCFYCNTRFPLSVEKARINNYDFTYGQFLNILLRMNKIFSLCVGKKKHAFGGRDTISPIESQVSNIFIPNDFPQSGDETYNLYKSFHFLSRSDPFVRRAIYSIADISGTPLTEGQIVNFERTYCQPLSDMNLSDSEGKNLHQYRNFNSNMGLIHTPYSEKYLPSEKRKKRILCLKKCVEKGQMYRTFQRDSAFSTLSKWNLFQTYMPWFLTSTGYKYLNLIFLDTFSDLLPILSSSQKLVSIFHDIMHGSGISWRILQKNLCLPQWNLISEISSKCLHNLLLSEERIHRNKNNESPLISTHLRSPNVREFLYSTLFLLLVAGYLVRTHLLFVSRVSSELQTEFEKVKSLIIPSSMIELRKLLDRYPTSEPNSFWLKNIFLAALEQLGDSLEEIRGSASGGNMLGPAYGVKSIRSKKKYLNINLIDIVDLIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVNGDWIDDKIESWVANSDSIGDEEREFLVQFSTLTTEKGIDQILLSLTHSDHLSKNDSGYQMIEQPGAIYLRYLVDIHKKYLMNYEFNTFCLAERRIFLAHYQTITYSQTSCGANSFHFPSHGKPFSLRLALSPSRAILVIGSIGSGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGFLIDDINIDDSDDIDASDDIDRDLDTELELLTMMNALTMDMMPEIDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESNYLSLGLLVNHLSMDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHLFTLSYTRGFHLEKKMFHTNGFGSITMGSNARDLVALTNEALSISITQKKSIIDTNTIRSALYRQTWYLRSQVRSVQDHGILFYQIGRAVAQNVFLSNCPIDPISIYMKKKSCNEGDFYLYKWYFELGTSMKKLTILLYLLSCSAGSVAQDLWSLPGPDEKNGITSYGLVENDSDLVHGLLEVEGALVGSSRTEKDCSQFDNDRVTLLLRPEPRNPLDMMQSGSCSILDQRFLYEKYESEFEEGEGEGALDPQQIEEDLFNYIVWAPRIWRPWAFLFDCIERPNELGFPYWSRPFWGKRIIYDEEDELQENDSEFLQNGTVQYQTRDRSSKEQGPFRISQFIWDPADPLFFLFKDQPPGSVFSHRELFADEEMSKGLLTSQTDPPTSIYKRWFIKNTQEKHFELLINRQRWLRTNSSLSNGSFRSNTLSESYQYLSNLFLSNGTLLDQMTKTLLRKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: BAP1_HUMAN
Sequence: MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ
What is the function of this protein?
Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1 (PubMed:12485996, PubMed:18757409, PubMed:20436459, PubMed:25451922, PubMed:35051358).  Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1) (PubMed:20436459, PubMed:25451922, PubMed:35051358).  Does not deubiquitinate monoubiquitinated histone H2B (PubMed:20436459).  Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains (PubMed:19188440, PubMed:19815555).  Deubiquitination of HCFC1 does not lead to increase stability of HCFC1 (PubMed:19188440, PubMed:19815555).  Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination (PubMed:19117993).  It however does not mediate deubiquitination of BRCA1 and BARD1 (PubMed:19117993).  Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytoplasmic sequestration (PubMed:24703950).  Acts as a tumor suppressor (PubMed:9528852).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase BAP1, BRCA1-associated protein 1, Cerebral protein 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family. BAP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly nuclear. Binds to chromatin. Localizes to the cytoplasm when monoubiquitinated by the E2/E3 hybrid ubiquitin-protein ligase UBE2O (PubMed:24703950).
Protein: PROT1_LYSEN
Sequence: MEQERIRQLAKLLAAGARARDAQAESMMDGGVAAAPAPAGQTLDVVEQALSTPPDDVDETQWRAAREQLLTHAHNGLVKLQRGDLQLDADEGCAMEAVIISDGSRPSFLLCDGEIDPKDPSIETWAGNIAAAQALGIAKLAAAVGRIQPKNGHASRYVGTGTLIDRDAGLILTNYHVIEQAQQNYGVAMTRNGDRLSVDGWLEIDFVGESCSLRTHRFRIVEVALPQGYGSTFHGIDAAVARIEPLPDSPALPDPVPLLSADAAYATGAISSLALIGFPARPSLQDGKDVDWSFVMRVLFGNRFGVKRLAPGQFTLPLGSHALDQGRRAIGHDATTFGGASGSLLMSWLDDRTPSFALHFGGATGVSNYALSFAAERNALSAIGARF
What is the function of this protein?
Possibly a dedicated protease for substrate gasdermin bGSDM; cleaves the bGSDM precursor, releasing the pore-forming moiety, which integrates into the membrane and triggers cell death.  Involved in defense against bacteriophages.  When this probable 4 gene operon (bGSDM-FE772_23060-FE772_23065-FE772_23070) is inserted into E. coli it provides nearly 100-fold protection against phages T5 and T6 and about 8-fold against phage T4.  The operon without bGSDM no longer protects against phage.
What are the official names of this protein?
Probable serine protease FE772_23060, Trypsin-like protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: T23O_BURCM
Sequence: MQPPGDNAPAGCPFSGAHAAQPAHEAPHVPGDAAGEAGWHDAQLDFSKSMSYGDYLSLNSILDAQHPLSPDHNEMLFIIQHQTSELWMKLALFELRGALDAVRGDALPPAFKMLARVSRILEQLVQAWNVLSTMTPSEYSAMRPYLGQSSGFQSYQYRQLEFLLGNKNVQMLQPHAHRPDILEQVRATLEAPSFYDEVVRLLARRGFPIAPERLERDWTQPMRHDETVEAAWLEVYRHPQQHWELYEMAEELVDLEDAFRQWRFRHVTTVERIIGFKQGTGGTSGAPYLRKMLDVVLFPELWHVRTTL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: MTMR2_DANRE
Sequence: MEESASVDSVESLCSSTTTRSDRSSGPKVSDTELRSKGRPIEKMYKDPSKGELPLLPVELVQESAKDVTYICPFIGPIRGSLTVTNYRLFFRCTDREPVFGLDLPLGVLSRVEKIGAATGRGDVSYGLACKDMRNLRFVHKEPDDSLKKSVFEVLMKFAFPVSNNMSLFAFEYKQVFPENGWKVYDPLAECKRQGLPNESWRISKLNDHYELCDSYPATLVVPVTITDDELRRVSSFRAKGRIPVLSWIHPESQAAVVRSSQPMVGQNGRRCKEDEKLLQAIMDANAQSHKLFIFDARPSVNAAANKMKGGGFESEDAYQNAELVFLDIHNIHVMRESLRKLKEVVYPNIEESHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLALIMLDSHYRTIRGFQILVEKEWLSFGHRFQQRVGHGDKNHTDVDRSPIFLQFIDCVWQMTRQFPAAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRLKEEIPKRTVSLWSFVNSQLEEFVNPLYVHYSSHVLFPTVGIRHLQLWVSYYIRWNPRMRPQEPVHQRYKELLAKRAELQKRVEELQREVSSRTASSSSERAGSPTRSITPVQTFV
What is the function of this protein?
Phosphatase that acts on lipids with a phosphoinositol headgroup.  Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate (By similarity).
What are the official names of this protein?
Myotubularin-related protein 2, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome membrane; Peripheral membrane protein. Note=Partly associated with membranes.
Protein: GLGB2_STRCO
Sequence: MALRDTSIPEPSGPVPPAPGACATAPPLDPTDRGRLLAGAHHDPHSLLGAHPVPGGIAFRVLRPFAREVGVVVDGERHTLASEEDGLFSGVLPLAGIPSYTLVVAYEQGETQETHDPYRFLPALGELDLHLIGEGRHEQLWQALGAEPMTHEGVTGTRFTVWAPNAQGVRVATDFTHWDGTAFPMRSLGSSGVWELFLPGVGEGTRYKFEIHSRYGHRFLKADPMARAAEEPPNTASVVTASRYEWGDAQWMRTRADTPVHEAPFSVYEVHLPSWRPGLTYRELAEELPAYVKDLGFTHVELMPVAEHPYGPSWGYQVTGFYAPTARLGSPDDFRFLVDALHRAGIGVIMDWVPAHFPKDDWALGRFDGDPLYEPGDSRRAEHPDWGTYTFDFARTEVRNFLVANAVYWCEEFHIDGLRVDAVASMLYLDYSRDSGQWEPNQYGGREDLAAMAFLQEMNATVYRRCPGVVTIAEESTAWGGVTRPTDTGGLGFGLKWNMGWMHDSLEYVAHEPVHRRYHHHEMTFSMVYAYSENYVLPISHDEVVHGKQALVSKMPGDWWQRRANVRAYLGFMWAHPGKQLLFMGQEFAQGAEWSEKQGPEWWLLDEGYHSAGDHRGVQDLVRELNTRYTRTPALWQRDTDPAGFRWVSVDAAEDNVFAFLRYGTDGTPLLAVSNFSPVVRHEYGLAVGDEAVAWQEVLNTDAEEYGGGGVGNPDPVKPEDGSIRITLPPLATVWLMPYAL
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB 2, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 2, Alpha-(1->4)-glucan branching enzyme 2, Glycogen branching enzyme 2, BE 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: NDUA9_BOVIN
Sequence: MAAAVHPRVVRVLPMSRSSVPALAASVFHSPPQRQLHHAVIPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPHRCEPYDTMHLRPMGDLGQIIFMDWNGRDKDSIRRAVEHSSVVINLVGREWETQNFDFEDVFVKIPQAIAQVSKEAGVEKFIHISHLNADIKSSSKYLRSKAVGEKEVRETFPEATIIKPAEIFGREDRFLNYFANIRWFGGVPLISLGKKTVKQPVYIVDVTKGIINAIKDPDARGKTFAFVGPSRYLLFDLVQYVFAVAHRPFLPYPLPHFAYRWIGRLFEISPFEPWTTRDKVERIHTTDKILPHLPGLEDLGVEATPLELKAIEVLRRHRTYRWLSSEIEDVQPAKTIPTSGP
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial, Complex I-39kD, CI-39kD, NADH-ubiquinone oxidoreductase 39 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA9 subunit family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL20_SALPA
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: HGD_ORYSJ
Sequence: MAMATATPAAQNEQQEKGGLEYVYLSGLGNSLSSEAVAGTLPRGQNSPLVCPLGLYAEQLSGTPFTAPRARNLRTWLYRIKPSVTHEPFHPRRPAHPRLIGDFDRTTTDTVATPTQLRWRPADVPPHHPPLDFIDGLYTVCGAGSSFLRHGYAIHMYAANKSMDGCAFCNADGDFLIVPQQGKLLITTECGKLLVPPGEIVVIPQGFRFAVDLPDGPSRGYVSEIFGTHFQLPDLGPIGANGLASARDFLSPTAWFEQVHRPGYTIVQKYGGELFTATQDFSPFNVVAWHGNYVPYKYDLSKFCPFNTVLFDHADPSVNTVLTAPTDKPGVALLDFVIFPPRWLVAENTFRPPYYHRNCMSEFMGLIYGIYEAKADGFLPGGASLHSCMTPHGPDTKTYEATISRPDANEPSRLSGTLAFMFESALIPRVCQWALDSPSRDLDYYQCWIGLKSHFSHDNGGATSEEPCRK
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: MNMG_PSEMY
Sequence: MDFPSRFDVIVIGGGHAGTEAALAAARMGVKTLLLTHNVETLGQMSCNPAIGGIGKSHLVKEIDALGGAMATATDKGGIQFRILNSRKGPAVRATRAQADRVLYKAAVREILENQANLWIFQQAADDLIVENAQVKGVVTQMGLRFHADSVVLTTGTFLGGLIHIGLQNYSGGRAGDPPSMALAHRLRELPLRVGRLKTGTPPRIDGRSVDFSVMTEQPGDTPTPLMSFLGKREHQPKQISCWITHTNARTHEIIAANLDRSPMYSGVIEGVGPRYCPSIEDKIHRFADKDSHQVFIEPEGLTTHELYPNGISTSLPFDVQLQIVRSIRGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGCNAALRAQGKEAWCPRRDEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKGRELGLVDDERWAAFEAKREGIVREEQRLKSTWVRPGTPQGDAIAARFGTPLAHEYNLLNLLARPEIDYAALAEITESPAVDNQVAEQVEIKTKYAGYIDRQQDEIARLRASEDTKLPEDLDYSAISGLSKEIQFKLGNTRPATLGQAGRIPGVTPAAISLLLIHLKKRSAGQKLEQSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.