PharMolix/UniProtQA huggingface dataset:
Protein: DTD_TOLAT
Sequence: MIALIQRVSEARVVVDGAVTGEISNGLLVLLGVERDDDVAKADKLAHRVAGYRVFSDADGKMNLNVQQVNGSILVVSQFTLAADTRKGMRASFAERNADPAVAEALYEHFIAQIAGKEIPVASGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GOLI4_HUMAN
Sequence: MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQLQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
What is the function of this protein?
Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi.
What are the official names of this protein?
Golgi integral membrane protein 4, Golgi integral membrane protein, cis, GIMPc, Golgi phosphoprotein 4, Golgi-localized phosphoprotein of 130 kDa, Golgi phosphoprotein of 130 kDa.
What is the protein family that this protein belongs to?
Belongs to the GOLIM4 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single- pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Membrane; Lipid-anchor. Note=Localizes to cis and medial Golgi cisternae. Probably cycles between early Golgi and distal compartments like endosome.
Protein: PCY2_BOVIN
Sequence: MIRNGHGEAGGAKRPGPRARRAVRVWCDGCYDMVHYGHSNQLRQARAMGDHLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTVDGRDTYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMSSEYREYADSFGKCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLEKVYGLAERPYVIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYSVTAELLDHFKVDLVCHGKTEVVPDKDGSDPYEEPKRRGIFCQVDSGNDLTTDLIVQRIIKNRLEYEARNQKKEAKELAFQEAMRRQEAQPEREIDCDF
What is the function of this protein?
Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway.  Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally stabilizing membrane-anchored proteins, and participates in important cellular processes such as cell division, cell fusion, blood coagulation, and apoptosis.
What are the official names of this protein?
Ethanolamine-phosphate cytidylyltransferase, CTP:phosphoethanolamine cytidylyltransferase, Phosphorylethanolamine transferase.
What is the protein family that this protein belongs to?
Belongs to the cytidylyltransferase family.
Protein: YK58_YEAST
Sequence: MENDKASHASPSIGVNEFVVQGEISIDDSERSVKSVSVSISDDEDSKTDVQDNMATPSTRSKFQTDLAIDNRLLEKDPKYKKLFTEKRRRRRPESCINLMTKGKGTGQKDNINDQIFSLRILPGSDLNSLKDSLWIIKISTQPDVEKTIARAFSDFYWLYHQLQNNHWGKTIPPPTRSNILVEKDEFAINHLFMIRNNEKYDPIFNFKPEYIISLQLMAMIKHIFNDKVLRLDSNFIDFISWDDDLPESLQIVVDDSTFTGDKILMTSSQFRELKEFHKQSKKVESITNSHASLIPVTELTEIYISPTKLFSRKDYQRLFQPQSTDNTFNNNDPLIQEWIPKSKTLFTSLSFGSSAPTYQEASTEIQACHDWVSISKEQWKQLLYHVLQYIVDEAVKVNSVINEFTECLKQISLDEVIRANSELFLKFSKLNESFLKKFKGASRQDILKLIILFDENVRFCESFESILNQRLKLGKILSIIEVDLDKKKNFLDKLSPGNNNSNNEDLKIRTAEDEYRIVLKRYNRVKQSWEKIMEDILNERKEFEKREAAEVNSCLKSIRDLNMDEKKHYLQLWQDFVPDEHISQ
What are the official names of this protein?
Uncharacterized protein YKR078W.
Protein: CSSC1_ECOLX
Sequence: MKSKLIILLMLVPFSSFSTENNFEINKTRVIYSDSTPSVQISNNKAYPLIVQSNIWDENNNKNHDFIATPPIFKMESESRNIIKIIKTNIKLPDSQESMRWLCIESMPPTEKSTKINRKEGRTDSINISIRGCIKLIYQPASVPSPVFNNIVEKLKWHKNGKYLVLKNNTPYYISFSEVFFDSDKVNNAKDILYVKPYSEKKIDISNRIIKKIKWAMIDDAGAKTKLYESIL
What is the function of this protein?
Involved in the biogenesis of the CS6 fimbria.
What are the official names of this protein?
Chaperone protein CssC.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ILVD_PECCP
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDNDFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDEQSEQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVGLAKRYYEQDDESVLPRNIANKAAFENAMILDIAMGGSTNTVLHLLAAAQEGEVDFTMTDIDRLSRQVPHLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNREVNNVLGKTLPETLEAYDVMLTQDDSVKSMYSAGPAGIRTTQAFSQDCRWDSLDTDRQEGCIRSREFAYSQDGGLAVLYGNLAENGCIVKTAGVDEGSLVFRGPAKVYESQDDAVDAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTTYLKSMGLGKSCALITDGRFSGGTSGLSIGHASPEAASGGTIALVQDGDIIAIDIPNRSIALVLDDNALASRRAAEEARGDQAWTPHNRERQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RL10_LEUMM
Sequence: MSEKAIAVKAQKVEEIADQFKAAASAVVVDPRGLTVAQSTELRHQLREEGVVLEVIKNKVLTRAAEKAGYAELNDIFAGPSAVAFSNDDAVAPARILKKFADENEALEIKGGVVDGTIANIDDINKYASLPSREGLLGQLMAEFQFSIRSFAYAVKAVQDKLEEESAAPAAEASTDAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CO2FA_CONMI
Sequence: MEKLTVLILVATVLLTIQVLGQSDRDKHLKRRPKQYATKRLSARMRGHRQCTGAGYECEETPECCPNLTCKCSGSPLCTRYSCQA
What are the official names of this protein?
Conotoxin Ml15a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPB_BRUSU
Sequence: MGLVVVGAGGRMGQTLIRTIQSIEGAKLVGAIERSGSPFLGKDAGEVTGIGTLGVAITDDPLPVFAKAHGVLDFTSPAASVEFAGLAAQARIVHVTGTTGCSAEDDEKIRAAARHATIVKSGNMSLGVNLLSVLVQKAAEALGPEDFDIEILEMHHRHKVDAPSGTALLLGEAAARGRDIALADNSVRVRDGYTGPRETGAIGFATLRGGSVIGDHSVILAGTGERVVLSHHAEDRSIFARGAIKAALWAHGKKPGLYSMLDVLGLNT
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_STRPJ
Sequence: MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIRVEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSKLVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGKGIRYVGEFVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL13A_CYAPA
Sequence: MFEKVVVVDCRGHLLGRLAATLAKELLNGQRVVAVRTEEINISGSLFRNKLKFHAFLKKRMNTNPRRGPFHFRSPARILWRTIRGMIPHKTPRGAAALERLKAFEGVPPPYDKMKRMVIPQALRVLRLKPGRKFCVLGRLATEVGWRHSDLVTRLEEKRKTKSAAFYARKKTLVNLRAKAAVAVASKTANIQKELDHYGF
What are the official names of this protein?
60S ribosomal protein L13a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: NHAP2_YERE8
Sequence: MDAITINSLFLIGAVLVGASILLSSLSSRLGIPILVIFLAIGMLAGTDGIGGIAFDNYPVAYLVSNLALAVILLDGGMRTRASSFRVALWPALSLATVGVLITAGLTGLAAAWLFDLDIIQGLLIGAIIGSTDAAAVFSLLGGKGLNERVSATLEIESGSNDPMAVFLTITLISMISAGESSLSWMFLVHLIQQFGLGIIIGLGGGSLLLLLINRIELPSGLYPLLAVSGGILVFSLTTAMNGSGILAVYLCGLMLGNRPIRNRAGILQTFDGLAWLSQIGMFLVLGLLLNPSELLPIAIPALILSLWMILFARPLSVFIGLLPFPSFNLRERIFISWVGLRGAVPVILAVFPMMAGIPHANLFFNVAFFVVLVSLLLQGTSLSFAARKTKLVVPPALAPVARIGLDIDKNNQWEQFIYQLSSDKWCIGAALRDLKMPQETRIAALFRGKDLLHPNGNTRLKEGDILCVIGQEHHLPALGKLFSQSPSIQLDERFFGDFILDADAKLDDISQIYGLNLEQGVDKQQTLGQFVLYLFGGEPVIGDQIEWDGLTWTIAEMESDRVSRVGVKIVTDKA
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGCA_BOVIN
Sequence: MTTLLLVFVTLRVITAAISVEVSEPDNSLSVSIPEPSPLRVLLGSSLTIPCYFIDPMHPVTTAPSTAPLAPRIKWSRISKEKEVVLLVATEGRVRVNSAYQDKVTLPNYPAIPSDATLEIQNMRSNDSGILRCEVMHGIEDSQATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQGGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYLHANQTGYPDPSSRYDAICYTGEDFVDIPESFFGVGGEEDITIQTVTWPDVELPLPRNITEGEARGSVILTAKPDFEVSPTAPEPEEPFTFVPEVRATAFPEVENRTEEATRPWAFPRESTPGLGAPTAFTSEDLVVQVTLAPGAAEVPGQPRLPGGVVFHYRPGSSRYSLTFEEAKQACLRTGAIIASPEQLQAAYEAGYEQCDAGWLQDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPPSETYDVYCYVDRLEGEVFFATRLEQFTFWEAQEFCESQNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLLDPLSRHHAFCFRGVSAAPSPEEEEGSAPTAGPDVEEWMVTQVGPGVAAVPIGEETTAIPGFTVEPENKTEWELAYTPAGTLPLPGIPPTWPPTGEATEEHTEGPSATEVPSASEKPFPSEEPFPPEEPFPSEKPFPPEELFPSEKPFPSEKPFPSEEPFPSEKPFPPEELFPSEKPIPSEEPFPSEEPFPSEKPFPPEEPFPSEKPIPSEEPFPSEKPFPSEEPFPSEEPSTLSAPVPSRTELPSSGEVSGVPEISGDFTGSGEISGHLDFSGQPSGESASGLPSEDLDSSGLTSTVGSGLPVESGLPSGEEERITWTSAPKVDRLPSGGEGPEVSGVEDISGLPSGGEVHLEISASGVEDISGLPSGGEVHLEISASGVEDLSRIPSGEGPEISASGVEDISGLPSGEEGHLEISASGVEDLSGIPSGEGPEVSASGVEDLIGLPSGEGPEVSASGVEDLSRLPSGEGPEVSASGVEDLSGLPSGEGPEVSVSGVEDLSRLPSGEGPEVSASGVEDLSRLPSGEGPEISVSGVEDISILPSGEGPEVSASGVEDLSVLPSGEGHLEISTSGVEDLSVLPSGEGHLETSSGVEDISRLPSGEGPEVSASGVEDLSVLPSGEDHLEISASGVEDLGVLPSGEDHLEISASGVEDISRLPSGEGPEVSASGVEDLSVLPSGEGHLEISASGVEDLSRLPSGGEDHLETSASGVGDLSGLPSGREGLEISASGAGDLSGLTSGKEDLTGSASGALDLGRIPSVTLGSGQAPEASGLPSGFSGEYSGVDLESGPSSGLPDFSGLPSGFPTVSLVDTTLVEVVTATTAGELEGRGTIDISGAGETSGLPFSELDISGGASGLSSGAELSGQASGSPDISGETSGLFGVSGQPSGFPDISGETSGLLEVSGQPSGFYGEISGVTELSGLASGQPEISGEASGILSGLGPPFGITDLSGEAPGIPDLSGQPSGLPEFSGTASGIPDLVSSAVSGSGESSGITFVDTSLVEVTPTTFKEEEGLGSVELSGLPSGELGVSGTSGLADVSGLSSGAIDSSGFTSQPPEFSGLPSGVTEVSGEASGAESGSSLPSGAYDSSGLPSGFPTVSFVDRTLVESVTQAPTAQEAGEGPSGILELSGAPSGAPDMSGDHLGSLDQSGLQSGLVEPSGEPASTPYFSGDFSGTTDVSGESSAATSTSGEASGLPEVTLITSELVEGVTEPTVSQELGQRPPVTYTPQLFESSGEASASGDVPRFPGSGVEVSSVPESSGETSAYPEAEVGASAAPEASGGASGSPNLSETTSTFHEADLEGTSGLGVSGSPSAFPEGPTEGLATPEVSGESTTAFDVSVEASGSPSATPLASGDRTDTSGDLSGHTSGLDIVISTTIPESEWTQQTQRPAEARLEIESSSPVHSGEESQTADTATSPTDASIPASAGGTDDSEATTTDIDECLSSPCLNGATCVDAIDSFTCLCLPSYQGDVCEIQKLCEEGWTKFQGHCYRHFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGEDCVVMIWHEKGEWNDVPCNYQLPFTCKKGTVACGEPPVVEHARIFGQKKDRYEINALVRYQCTEGFIQGHVPTIRCQPSGHWEEPRITCTDPATYKRRLQKRSSRPLRRSHPSTAH
What is the function of this protein?
This proteoglycan is a major component of extracellular matrix of cartilagenous tissues.  A major function of this protein is to resist compression in cartilage.  It binds avidly to hyaluronic acid via an N-terminal globular region.  May play a regulatory role in the matrix assembly of the cartilage.
What are the official names of this protein?
Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP.
What is the protein family that this protein belongs to?
Belongs to the aggrecan/versican proteoglycan family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RS16_BRUA4
Sequence: MSLKIRLARAGSKKRPYYHIVVADVRSPRDGRFIETVGAWNPMLAKDAERVKLDADRIQHWIAQGAQPTDRVLRFLDQAGLAKRPTRSNPTKGEPGKKAQERLAMAKQAEEEAAAKAAEAAAAAAAPAEEAASE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PID2_CAEEL
Sequence: MTVIIASHWGPQSKQMLPPEPPRIILREVPVQNNQKEHPPVQEIKTVSSKSKEHRVSSSRKIPDHFDVGPRFYMNVPADGSEVFEDDEKDVENECWAVIERIGSEDDKFEASELVEYRDHDWYIALAINKEKTPDKANYQHLLYSYRGGIQRIILTPQQTDSIDKTPLVKYKIIGDGLYEVLPIHSSLPQTGLISPKYRYNKGVELRIFGIVNWIDFVLDDDHQTHRTMVWTDAVGPIYLSAADRANIRRKLLLTEMQIFAPLRMCHITVKAEFNFSIPDGSPIQWTISSFQPLIEESEKDPNIGRNLWPARVLRFDDLVVTKKTPNGYWLKSQRLEGHVNVFAGANQIGIIESAGEKYATKGSMMAFVVPCYQNSTFAYFEALIAGPPRVVMIITEGRFLNYCPKTWPPSVRKMRDQYQKEHVLKSEVRSSPICMKQPDYCLKSLRGFSECPF
What is the function of this protein?
Involved in gene silencing mediated by a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs) and that guide the Piwi protein prg-1 to its DNA targets for silencing (PubMed:33438773, PubMed:33231880).  Not required for the biogenesis of 21U-RNAs (PubMed:33231880).  May also be involved in gene silencing mediated by 22G-siRNAs (a class of 22 nucleotide endogenous small interfering RNAs (siRNAs) that possess a triphosphorylated guanine residue at the 5'-end) and 26G-siRNAs (a class of 26 nucleotide siRNAs that possess a guanine residue at the 5'-end) (PubMed:33231880).  Required for the biogenesis of secondary and tertiary 22G-siRNAs from many loci (PubMed:33231880).  Specifically, promotes the production of 22G-siRNAs from the 5' end of target mRNAs (PubMed:33231880).  May play a role in the production of 26G-siRNAs (PubMed:33231880).  Plays a role in small RNA-directed transgenerational epigenetic inheritance (also called RNAe) over several generations and germline immortality (PubMed:33438773, PubMed:33231880).  Together with the argonaut protein hrde-1, promotes the silencing of the DNA transposable element Tc1 (PubMed:33231880).  Required for the formation of liquid-like condensates in the cytoplasm called Z granules, playing a role in maintaining their assembly, viscosity and morphology in adult germ cells, and localization in early embryos (PubMed:33438773, PubMed:33231880).
What are the official names of this protein?
Protein pid-2, Z granule surface protein 1, piRNA-induced silencing defective protein 2.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasmic granule. Note=Localizes to perinuclear granules, adjacent to P granules in adult germ cells (PubMed:33438773, PubMed:33231880). These perinuclear granules segregate with germline blastomeres during embryonic development (PubMed:33438773). Localizes to the outer periphery of Z granules, which are liquid-like condensates in the cytoplasm (PubMed:33438773).
Protein: RBS_PHYPA
Sequence: XQVWNPIGQPKFETF
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARVC_HUMAN
Sequence: MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQQPGMVSGGMGSGQPLPMAWQQLVLQEQSPGSQASLATMPEAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPDGLPLLDGGPPLGPFADGALDRHFLLRGGGPVATLSRAYLSSGGGFPEGPEPRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPPGGRSLPERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGELADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALVASSQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALGPDGYSTVDRRERRPRGASSAGEASEKEPLKLDPSRKAPPPGPSRPAVRLVDAVGDAKPQPVDSWV
What is the function of this protein?
Contributes to the regulation of alternative splicing of pre-mRNAs.
What are the official names of this protein?
Splicing regulator ARVCF, Armadillo repeat protein deleted in velo-cardio-facial syndrome.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Nucleus. Cytoplasm. Note=In heart, localizes at area composita, the mixed-type junctional structure composed of both desmosomal and adherens junctional proteins.
Protein: DNAJ_MYCPU
Sequence: MNKKEDYYKILGIDKSANEKEIKKAYRKLAMEHHPDRSSSKESEAKMREINEAYEVLSNPEKKAIYDKYGHEAANNPGFNGFNAGSAGFGNFGGFSNFGGFDSIFEEFFGGSRSHSKQNSNYPYPGESYSTQVKISFLDSVHGRVISQKLDKYKDCESCNGTGARSKSDIKTCSTCNGRGSVEKLVNSLFGKIKQSVTCSTCNGLGQEITHKCPSCKGAKKIKESISQKISIPAGVISGQEVLLRGFGGPGFNGGPNGDLYIRVYVTEHPYYQRINDDIYVDFPISIVNLILEKPVVVPTPYGDEKIKIKSTFKNDQIITFKGKGFKRKNRVGDLKIRLKFEIPNFSSKVKKNLESLLSETNDSINEDFVKKVNSIK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGIB_ECO27
Sequence: MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETVSLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKYTDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSSRSMGG
What are the official names of this protein?
UPF0441 protein YgiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: QUEC_BACVZ
Sequence: MKKEKAVVVFSGGQDSTTCLLWALQNFEEVETVTFHYNQRHQEEIDVAKSIAEKLGVKNHLLDMSLLNQLAPNALTRDDIEIEAKDGELPTTFVPGRNLVFLSFASILAYQIGARHIITGVCETDFSGYPDCRDEFVKSCNVTVNLAMEKPFVIHTPLMWLNKAETWKLADELGALDFVKNNTLTCYNGIIADGCGECPACLLRNKGYDEYMKMKGERN
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: SYT_LEUCK
Sequence: MSEISLTFPDGAVKVFPEGTTPLPVAESISKSLAKKSVSAKLHGAYVGMHDMIPASGDFQLITTSDDEAISLLRHAASHLLAQALKRIPKFANMHFGVGPFIDNGFYYDTDNGAGNQVSVEDFPEIEAMMHKIVKEDLPIVSREITREEALSMFAEDPYKIALISDLPEDEKITIAVQGDHIELDKGGLVPSTGWIKHFKLTSVAGAYWRGKSSNPMMQRIYGVAEWKQADVDAEIQRREEAKERDHRTIGRDMDLFFTSQEVGSGLPVWLPNGATIRRQVERYIIDKELANGYQHVYTPVLSNLNLYKTSGHWDHYREDMFPPMDMGEGEFLELRPMNCPSHIMVFNHKPRSYRELPIRIAELGMMHRYEKSGALTGLSRVREMTLNDGHTFVEPEKLEEEFKSILTMMMGVYRDFNITDYRFRLSYRDPENTEKYFDDDDMWEKSQAQLKRAMDDLKLDYYEAEGEAAFYGPKLDVQTKTALGSEETMSTIQLDFLLPERFNLTYIGADGQDNHRPVMLHRGIVGTMERFTAYLIEMYKGAFPTWLSPLQVQIIPVNLGAHGDYANDIQAQLQAAGLRAHVETKDAKMGYLIREAQTNKIPYTLVLGDSEVDGQTVTVRKYGEEKTRTMRFADFQSEILADVANYSRPVND
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.