PharMolix/UniProtQA huggingface dataset:
Protein: RLMN_SHISS
Sequence: MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_LISIN
Sequence: MSKDMLVNDGIRAREVRLIDQDGEQLGVKSKIDALQIAEKANLDLVLVAPTAKPPVARIMDYGKFRFEQQKKDKEARKNQKVIVMKEVRLSPTIDEHDFDTKLRNARKFLEKGDKVKCSIRFKGRAITHKEIGQKVLDRFAKACEDLCTIEQRPKMDGRSMFLVLAPLHEK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_STRA5
Sequence: MNSINIAIDGPASSGKSTVAKIIAKNLNYTYLDTGAMYRCATYLALQHGYEAQDVSKILGLLAERPISFGKAEDGSQTVFLGTEEVTLAIRQNDVTNNVSWVSAIPEIREELVNQQRRIAKDGAIIMDGRDIGTVVLPDAELKIFLVASVDERAERRFKENQEKGIESDFETLKSEIAARDYKDSHREVSPLKAAEDAIEFDTTGVSIEGVVTFIQEKAEKIIDMKN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNB_YEAS2
Sequence: MSSQDVLIHSDDPCHPANLICTLCKQFFHNNWCTGTGGGISIKDPNTNYYYLAPSGVQKEKMTPEDLFVMDAQTLEYLRSPKLYKPSACTPLFLACYQKKDAGAIIHTHSQNAVICSLVFGDEFRIANIEQIKAIPSGKVDPVTKKPMALSFFDTLKIPIIENMAHEDELIDDLHKTFKDYPDTCAVIVRRHGIFVWGPTIDKAKIFNEAIDYLMELAIKMYQMGIPPDCAIGEEKKHLKMASP
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL88_HCMVM
Sequence: MMEAAAAAAAAFRPEERPTPGWHDAALLMDDGTVREHAFRNGPLSQLIRRVLPPPPDAEDDVVFASELCFYCSGRFNRRSSVFSIYWQKHSDLVYALTGITHCAKLVVECGQLGSSRLRWRDGDASGEERRGDDDSRDELYDVPGIYMIRVNDGGSTGPRHVIWPGTSVLWAPDVVITTVQRRISAARALVNTFRQYFFLLERRSHEELVLCPPEMEERLAPLLQSATRGDSDMFDGVVASAYHRLRMSNIPRSSARLLEHCVGLAGAKKLLLLDVPRLENYFLCQVCLYELDEDEMGEEMLGMLAGKPEDAAVSGASGGFLLHRKTMKLAACLCLLLNSLHLHQEALEALDPPPPRVEENDLVNVVLRRYYRSHGGVQARTLAAARALLADYAETFSPLGSFTRLGYDRLVSADAGVSRRHLVALLRA
What is the function of this protein?
Plays a role in incorporating a subset of tegument proteins into the virion.
What are the official names of this protein?
Protein UL88.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U59/UL88 family.
What are the subcellular locations of this protein?
Virion. Virion tegument. Host cytoplasm. Note=Accumulates in a juxtanuclear location reminiscent of the viral cytoplasmic assembly compartment.
Protein: ARGB_CLAM3
Sequence: MTAITQDAAERDQAQAESKAATLIESLSWLQRFHDRIVVVKFGGNAMVDEELTRTFAEDVVYLRYAGLRPVVVHGGGPQISAMLTRLGIESEFRGGYRVTTPEVLEVVRMVLTGQVSRDVVRGINAHGPLAAAVSGEDAGLFTGRRRGAVVDGVEVDLGLVGDVVAVDPTAVLAQLDAGRIPVVSSIAPDESDPAVSLNVNADAAAAALAVALGAEKLVILTDVAGLYRDWPDRGSLVSDIRSDELRALLPSLESGMIPKMAACLEAVDGGVPKAAIIDGRIPHSMLLEIFTTNGIGTEVVPA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_NEIM0
Sequence: MLKFTLHKKDGYARRGTLELNHGKIETPVFMPVGTYGSVKAMNPQNLHDIKAQIILGNTYHLWLRPGLEVIGQFGGLHGFIGWDKPILTDSGGFQVFSLSDMRKLTEEGCTFKSPINGDKLFLSPEISMKIQTVLNSDIAMQLDECTPGEATREQARKSLQMSLRWAERSKKAFEDLKNPNALFGIVQGAMYEDLREESLRGLEQFDFPGLAVGGLSVGEPKPEMYRMLRAVGPILPEHKPHYLMGVGTPEDLVYGVAHGIDMFDCVMPTRNARNGWLFTRFGDLKIKNAKHKLDKRPIDESCTCYACQNFSRAYLHHLHRAGEILGAQLNTIHNLHFYQVIMAEMRDAIEQGKFADWQAQFHENRARGTD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: DLTS_STRA5
Sequence: MFSDLRKKFVFLTMSILIVVVLFLFAVSNRYNQYWDEYDAYRIVKLVAKNDYLGIPGDEPIALVTIDNQKMVKIQSNNTDLTNDVIEKSSLKLLEQGKKSRKWKSFIYSIKEYKDKTYTIAIMDLASYEVPYARRFLILVFTIFGFCLLAAVSLYLSRFIVGPVETEMTREKQFVSDASHELKTPIAAIRANVQVLEQQIPGNRYLDHVVSETKRMEFLIEDLLNLSRLDEKRSKVNFKKLNLSVLCQEVLLTYESLAYEEEKCLNDTIEDDVWIVGEESQIKQILIILLDNAIRHSLSKSAIQFSLKQARRKAILTISNPSAIYSKEVMDNLFERFYQAKDDHADSLSFGLGLSIAKAIVERHKGRIRAYQEKDQLRLEVQLPIDGFWTNTMIN
What is the function of this protein?
Member of the two-component regulatory system DltS/DltR.  Regulates the expression of the dlt operon.  Probably phosphorylates DltR (By similarity).
What are the official names of this protein?
Sensor protein DltS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SURE_PROMP
Sequence: MESLNILISNDDGVFAEGIRALAKSALKKGHKVTVVCPDQERSATGHGLTLQSPLRVERADELFDKGIKAWGCSGTPADCVKLALSELLDKKPDLVLSGINHGPNLGTDIFCSGTVAAAMEGTLENVPSMAISVASFKWKNFEFAGEIAMNIAEQAIKDSWPKSLLLNLNIPPCERNKIKELSWTRLSIRKYKNQFSKREDPRGDDYYWLAGEAVLDLKSKGDGPKNWPSDVSQIQENKISLTPVEPDLFWRGSIDVLPKINTSFINAS
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_SYNP6
Sequence: MAIAEEPAQAPVIQRIALVIQYLGQGFCGWQRQPRQRSVQGELESAIAAVVGHPVSVQSAGRTDTGVHAAAQVAHFETTSPIPAHRWPSVLNGRLTPDLNIRAAAIVPANWHARFSASYRRYRYTIYTDPCPNLFLNSYVWHYYQAPLCENQMQAALQTLVGYHHLAAFQRSGSKRQHAWVHVQDAWVRRRDSLIEIEVQASGFLYGMIRLLVGLLVQVGEGSRSLESFTDIWVNQRRDRVRHAAPPQGLCLLRIGYPDSPFPVDAWFDTQPLFVLPSSRNDSESLSPCAVSLG
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CETZ_PYRFU
Sequence: MRAIIIGIGQCGTKIADIFSLVDFEALAINTSRGDLEYLKHIPPDRRILIGESIVGGKGVNANPVLGREAMKRDLPMVMKKISSLVGFEDVDIFFLTFGFGGGTGAGGTPVLAEALKEEYPDSLVVAIGALPLKEEGIRPTINAAITIDKLSKIVDSIIAIDNNKLKESNEDISQAYERINYAIVERIASLLALIDVPGEQTLDASDLKFVLRAMGSFATVGYAKADATKIKSLSRLIIRSFENEGLYLDVNIESALYGLVAIHGPPEALKANEIFEALNELTQRIRGKQIFRGFYPDPREREVEVVTLLSGIYESKSIEEIVITAKKYAQEFLKAKEEGESKKKKLLSGLPDFDDIYPGEADDQS
What is the function of this protein?
Involved in cell shape control.
What are the official names of this protein?
Tubulin-like protein CetZ.
What is the protein family that this protein belongs to?
Belongs to the CetZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_NOCFA
Sequence: MGESMTWVQALVLGLVQGLTEFLPISSSAHLRIVSSVFFGEDAGASFTAVTQLGTEAAVLVYFAKDIWRILVAWTTTLWDKARAATGPRVPIHDRPTTRLPVLTADNEHRFAAEAQRELDYRIGWYVIIATIPIGVLGFLFKDEIRTGARNLWLVSFMLIAFALVIAAAEHYGAKRRPIEQLTTRDGLVMGFAQCLALIPGVSRSGATSSAGLFLGLEREAAVRFSFLLAIPAVTASGLFSLPDAFEPAGEGLNASGPQLLVATIVSFVVGYASVAWLLKFVARHSLNWFVGYRIVLGLVIMGLLGAGVISAT
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLRX_VERFO
Sequence: MAMIKAQELVSSNSVVVFSKTFCPYCTSVKQLLNQLGAQFKVIELDSESDGSDLQNALAEWTGQRTVPNVFIGGKHIGGCDKTTGMHQEGKLIPLLTEAGAVKA
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins (By similarity).
What are the official names of this protein?
Glutaredoxin.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CPYC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_STRAW
Sequence: MTRLILATRNAGKITELRAILADAGLTHDLVGADAYPDIPDVKETGVTFAENALLKAHALARATGLPAVADDSGLCVDVLGGAPGIFSARWSGRHGDDRANLDLLLAQLSDISEAHRGAHFACAAALALPDGTERVVEGQLRGTLRHTPTGTNGFGYDPVLQPEGETRTCAELSAEEKNAISHRGKAFRELVPVVRELLG
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: FUS_PIV5
Sequence: MGTIIQFLVVSCLLAGAGSLDPAALMQIGVIPTNVRQLMYYTEASSAFIVVKLMPTIDSPISGCNITSISSYNATVTKLLQPIGENLETIRNQLIPTRRRRRFAGVVIGLAALGVATAAQVTAAVALVKANENAAAILNLKNAIQKTNAAVADVVQATQSLGTAVQAVQDHINSVVSPAITAANCKAQDAIIGSILNLYLTELTTIFHNQITNPALSPITIQALRILLGSTLPTVVEKSFNTQISAAELLSSGLLTGQIVGLDLTYMQMVIKIELPTLTVQPATQIIDLATISAFINNQEVMAQLPTRVMVTGSLIQAYPASQCTITPNTVYCRYNDAQVLSDDTMACLQGNLTRCTFSPVVGSFLTRFVLFDGIVYANCRSMLCKCMQPAAVILQPSSSPVTVIDMYKCVSLQLDNLRFTITQLANVTYNSTIKLESSQILSIDPLDISQNLAAVNKSLSDALQHLAQSDTYLSAITSATTTSVLSIIAICLGSLGLILIILLSVVVWKLLTIVVANRNRMENFVYHK
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with HN at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: Y1750_CROS8
Sequence: MNKFLRHSLLLALLTGALSGVANAQTDKLIIESGDNARTRQDAAMDKEQWNDTRSLRQKVNKRTEKEWDKADVAFDAKDNCEKSANLNAYWEPNTLRCLDRRTGRVINP
What are the official names of this protein?
UPF0482 protein ESA_01750.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: PANC3_FRAAA
Sequence: MLRVLHTIEDVREQTREWRAAGSSIGCVMTMGALHEGHLSLVDAARRECDKVVLTLFVNPIQFGPSEDFDRYPRTEEADFRALRDRECDAVFAPATETIFPLGERRIDQVRTKVVVRGLTDVLCGPRRPGHFDGVTTEVLKMLHIVDCDRTYWGEKDYQQYAVIRAMVEDQGLPVKVVPCPTMRDVDGLALSSRNTYLDSGQRAIAPRLYAALRRGARRIAEQGIDVIGETTKQIAETLLAHGFDLVEYVEVYTGSLGPAVAGTPVEELRVFGAVRLGGARLLDNAAVADEVGG
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase 3, PS 3, Pantoate--beta-alanine ligase 3, Pantoate-activating enzyme 3.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITPK4_SOYBN
Sequence: MRLNGEISSGEEEEEEKQTGTTTFSSQKVVVGYALTSKKKKSFLQPSFTGLARNRGINFVAIDLNKPLPEQGPFDIILHKLSGEVWREIIEDYREKHPEVTVLDPPDAIQHLHNRQSMLQDVLDLNLSDCHGKVGVPRQLVITKEKDPSSIPYEVTKAGMKLPLVAKPLVVDGTAKSHELFLAYDEFSLSAVEPPLVLQEFVNHGGLLFKIYIVGETIKVVRRFSLPNISKRELSKVAGVFRFPRVSCAAASADDADLDPNIAEHPPRPLLERLARELRHRLGLHLFNIDMIREYGTKDVFYVIDINYFPGYGKMPGYEHVFTDFLLSLVESKCSNKKLAA
What is the function of this protein?
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4, Ins(3,4,6)P3 and Ins(1,3,4)P3 (PubMed:18474240).  May participate in an inositol lipid-independent pathway of InsP6 synthesis (PubMed:18474240).
What are the official names of this protein?
Inositol-tetrakisphosphate 1-kinase 4, GmItpk4, Inositol 1,3,4-trisphosphate 5/6-kinase 4, Inositol-triphosphate 5/6-kinase 4, Ins(1,3,4)P(3) 5/6-kinase 4.
What is the protein family that this protein belongs to?
Belongs to the ITPK1 family.
Protein: SYG_METM6
Sequence: MDKYDKIIDLTKRRGFLWNSFEIYGGIAGFFDYGPLGAILKNNVINTWRKHYIVNEGFYEIDSPTVTPYEVLKASGHVENFTDPLVECKGCLESFRADHIIEENVDVDTEGKTLQELQEMIEKNNIKCPKCGGEFKDVSTFNLMFATSIGPGGKRAAFMRPETAQGIFIQFKRISQFFRNKLPFGAVQIGKAYRNEISPRQGVIRLREFTQAEGEFFIDSRKKENFEKFESVKDTVLPLLSGKNQENESLSAEEKIVRMSLSDAVKNGIIAHEAIAYYIAVTKKFLMEIGIDESKLRFRQHLPNEMAHYAADCWDAELYTDRYGWIECVGIADRTNYDLLAHMKNSGEDLSVFVELDEEHEIEAYEIELNYKLVGRTFKGDAKVLEESLKELDDKKMEELVEALETEGKYTLKTCKRDFELLKEYLTAKKVKKIVKGEKIIPHVIEPSYGIDRITYCVMEHAFKEEEDRTVMGFSNAVSPIKVGVFPLVNKEGMPEIAMDLKNKLRENGLIAEYDDSGAIGRRYMRMDEVGTPFCITIDGETLVDNSVTIRERDSRAQFRIPINEVVSYIKDKL
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CONG_ARAHY
Sequence: MAKSTILVALLALVLVAHASAMRRERGRQGDSSSCERQVDRVNLKPCEQHIMQRIMGEQEQYDSYDIRSTRSSDQQQRCCDELNEMENTQRCMCEALQQIMENQCDRLQDRQMVQQFKRELMNLPQQCNFRAPQRCDLDVSGGRC
What are the official names of this protein?
Conglutin.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: MOAA_CAMLR
Sequence: MLVDSYGRVIDYLRISVTQRCNFRCLYCMPKTPFEWSAKENLLSFEELFMFVKVCIDEGVKKIRITGGEPLVRKDLYKFIAMISEYKQDIDLALTTNASLLKQQAKDLRQAGLKRINISLDTLKEDVAFKLAQKNILKDVLNGIDEALNLGFNVKFNTVALKGINDSEFIDLLEFAKVRKSQIRFIEFMENYHAYGDLKGLKSAEILNIIAQKYSFKQGEKSSNAPATIYELEDGYKFGIIDPHSHDFCDSCNRIRLSAEGLLIPCLYYDEALSIKKAIRNKDIAGACEVLKTVIKNKSEKNRWAENEANQSSTRAFYQTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: ATP8_LOXNO
Sequence: MPQLNPHPWFFIMLASWLTFSLIIQPKLLTFVTMNPPSNKPPIAPSTTPWTWPWT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RS6_LEPBA
Sequence: MRNYEITNILREGNVEETKSAVKELLSKYNFTIQGEEDWGSKRLWHPVGQDEQGHFTLIKCSGSPTEVAKIEHEFKLNVNILKTLVIRANG
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RS16_AGRRK
Sequence: MALKIRLARGGSKKRPYYHVVIADARSPRDGRFLEKVGSWNPMLAKDDAKRVELDADRIKHWLDNGAQPTDRVLRFLDEAGVAKREVKSNPEKAKPGKRAQERAAEKAQKAADAAAATAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RUTF_ECO26
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: RL14_CORGB
Sequence: MIQQESRLKVADNTGAREILCIRVLGGSTRRFAGIGDVIVATVKEATPGGNVKSGEIVKAVIVRTKKETRRADGSYISFDENAAVIIKNDNEPRGTRIFGPVARELREKKFMKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: BFR_RHOCA
Sequence: MKGDAKVIEFLNAALRSELTAISQYWVHFRLQEDWGLAKMAKKSREESIEEMGHADKIIARILFLEGHPNLQKLDPLRIGEGPRETLECDLAGEHDALKLYREARDYCAEVGDIVSKNIFESLITDEEGHVDFLETQISLYDRLGPQGFALLNAAPMDAAE
What is the function of this protein?
Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.
What are the official names of this protein?
Bacterioferritin, BFR.
What is the protein family that this protein belongs to?
Belongs to the bacterioferritin family.
Protein: GPX2_HYLLA
Sequence: MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI
What is the function of this protein?
Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides.  Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors.
What are the official names of this protein?
Glutathione peroxidase 2, GPx-2, GSHPx-2, Glutathione peroxidase-gastrointestinal, GPx-GI, GSHPx-GI.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PP1G_RAT
Sequence: MADIDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNATRPVTPPRGMITKQAKK
What is the function of this protein?
Required for normal male fertility.
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, PP-1G, Protein phosphatase 1C catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cleavage furrow. Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome, centromere, kinetochore. Nucleus speckle. Midbody. Mitochondrion. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Colocalizes with SPZ1 in the nucleus. Colocalizes with URI1 at mitochondrion. Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleolus to nuclear speckles. Shows a dynamic targeting to specific sites throughout the cell cycle. Highly concentrated in nucleoli of interphase cells and localizes at kinetochores early in mitosis. Relocalization to chromosome-containing regions occurs at the transition from early to late anaphase. Also accumulates at the cleavage furrow and midbody by telophase.