PharMolix/UniProtQA huggingface dataset:
Protein: ALGB_PSEPK
Sequence: MESAQDNQGRILLVDDESAILRTFRYCLEDEGYSVATANSAAQAETLLQRQVFDLCFLDLRLGEDNGLDVLAQMRIQAPWMRVVIVTAHSAIDTAVDAIQAGAADYLVKPCSPDQLRLATAKQLEVRQLSARLEALEGEIRKPKDGLDSHSPAMMAVLETARQVAITDANILILGESGTGKGELARAIHGWSKRARKACVTINCPSLNAELMESELFGHTRGAFTGASESTLGRVSQADGGTLFLDEIGDFPLTLQPKLLRFIQDKEYERVGDPVTRRADVRILAATNLNLEEMVRESRFREDLLYRLNVITLHLPPLRERSEDILILADRFLARFVKEYSRPARGFSDEARTALLNYRWPGNIRELRNVVERASIICPQERVEISHLGMGEQPAGSAPRVGAALSLDELERAHIGAVLAASDTLDQAAKTLGIDASTLYRKRKQYNL
What is the function of this protein?
Positive regulator of the alginate biosynthetic gene algD.
What are the official names of this protein?
Alginate biosynthesis transcriptional regulatory protein AlgB.
Protein: NTPP_XYLF2
Sequence: MLYLASRSLCRRQLLQRLDIPFQVIDLEIPEVRREDELPQDYVRRVAQEKAQVGLARVGDAFAPKVLGADTEVVLDGRVFGKPVDLAEAATMLAALSGRTHQVMTAVSLVAAGGVAAQVLVVSEVSFALLSQGQIARYVDSGEPMGKAGAYAIQGRGECFVSRLVGSYSGVMGLPLQQTAQLLATFEES
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAHS1_PARRC
Sequence: MSAEAMNMNMNQDAVFIPPPEGEQYERKEKQEIQQTSYLQSQVKVPLVNLPAPFFSTSFSAQEILGEGFQASISRISAVSEELSSIEIPELAEEARRDFAAKTREQEMLSANYQKEVERKTEAYRKQQEVEADKIRKELEKQHLRDVEFRKDIVEMAIENQKKMIDVESRYAKKDMDRERVKVRMMLEQQKFHSDIQVNLDSSAAGTETGGQVVSESQKFTERNRQIKQ
What is the function of this protein?
CAHS proteins are cytosolic heat soluble proteins that seem to contribute to the anhydrobiosis in tardigrades, but their specific mechanisms are yet to be identified (PubMed:28306513, PubMed:33545053).  It is possible that protection during anhydrobiosis might occur via the stabilization of vitrifying small molecules such as sugars, but not via the direct glass transition of CAHS proteins themselves (Probable).
What are the official names of this protein?
Cytosolic-abundant heat soluble protein 107838, CAHS 107838, Tardigrade-specific intrinsically disordered protein CAHS 107838, TDP CAHS 107838.
What is the protein family that this protein belongs to?
Belongs to the Cytosolic-abundant heat soluble protein (CAHS) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS2_SALTO
Sequence: MTYRPATDPPDLDTLTLGVEEEFLLLDSDTGESMPVAARVLDGLSGTAYEQSRREFRHSMVEMVTPVVSDLAELRRHLVALRTAAAEAAESAGAHLVAVGATPVNETHRTVPDEPRYHAMSRRFGPVAHDPAVCGCHVHVGLPDRELAVQVCNHLRPWLPVVQAITANSPLHDGQDTGHASWRAMQLERWPSIGPTPYFDSAADYDATVADLIKAGIMLDAGMVYWYVRPSAAFPTVEIRVGDVCPTVDDTVLVAALVRALVATLAADVRDGARATRIRGCLVSAAHWRAAHDGLDGDLVDLRTGHARPAWDLVDELFALVAPALERQGDRAYVLDQLARLRDEGTGAARQRRILERTGCDVRAVLAHLAAQTRPVPA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: DNLJ_WOLSU
Sequence: MNPDQYSQAIERLNAWAHAYYVLDAPLATDEEYDQLYHEALAFERQNPERIHPASPTQRIGGAPLEGFQKASHLERMWSLEDVFDFGELKSWAERLYKQFPHATFVCDPKFDGASLNLLYEEGRLVRAATRGDGLIGEDVTQNARTIPSIPLSIPLLERIEIRGEVVIPKEDFEKLQEERLRENESPFANPRNAAAGSLRQLDPAITAKRKLRFIPWGVGAHPFKTGSFFEIMKSLESYGFIRSPERTRCHNIHEIERVYALLVSERSTHPVMLDGMVVRVDEIAYQRELGYTIKAPRFACAYKFPAIEKKARLLSITLQVGRSGVVTPVANLEPVEIEGAMISRATLHNFDEIKRLDVREGDWVSLIRSGDVIPKIIQPFAHLRSGEEKPLSRPTHCPECGSELLVEEVLIKCQNLSCPARIKNSLIHFASKKALNIDGLGEKIIEQLFEAGLIKEFEDLFSLTKESLLSLEGFKEKKAQNLLDAIQGVRGCDLWRFINALGIEHIGEGAAKKLSHAFGLAFHLQNHEAIIGLEGFGEEMAQSLLEFCRVNHERIEHLLGLIEPLAPIQLTPQDSPIAGKSFVITGTLSAPREHFVELLTSLGAKVVSSVSKKSDFLLYGESAGSKLEKARELGVRCVNEEELGEILES
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: FDOH_ECOL6
Sequence: MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKACQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMHCSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKCTLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAGVGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHYVGVGPNRADEEENNLHEEKDEERK
What is the function of this protein?
Allows to use formate as major electron donor during aerobic respiration.  The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.  Electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit (By similarity).
What are the official names of this protein?
Formate dehydrogenase-O iron-sulfur subunit, Aerobic formate dehydrogenase iron-sulfur subunit, FDH-Z subunit beta, Formate dehydrogenase-O subunit beta.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GLPE_PECAS
Sequence: MEQFEAISIEQAHSRWQEGGVVVDIRDPQSFAAAHVPGATHLTNETLPDFVRGADFEAPVMVICYHGISSRNAAQYLISQGFDSVYSIDGGFEAWQHRYPQDTQA
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRL_BUFJA
Sequence: PEDKEQAQQIQHEDLLSLVLKVLRSWNDPLLHMVSEVQDIQEAPDTILWKAVEIEEQTKRLLEGMERIVGRIHPGDLENEIYSPWPGPSAAIPGDESSRLFAFYNLLHCLRRDSHKIDNYLKLLKCRLIHDGNC
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: STRP1_HUMAN
Sequence: MEPAVGGPGPLIVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRSILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDSNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ
What is the function of this protein?
Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the cortical actin filament dynamics and cell shape.
What are the official names of this protein?
Striatin-interacting protein 1, Protein FAM40A.
What is the protein family that this protein belongs to?
Belongs to the STRIP family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Enriched on the plasma membrane.
Protein: SRTB_LISMO
Sequence: MKIKSFLGKSLTLVVLGVFLFSGWKIGMELYENKHNQTILDDAKAVYTKDAATTNVNGEVRDELRDLQKLNKDMVGWLTIIDTEIDYPILQSKDNDYYLHHNYKNEKARAGSIFKDYRNTNEFLDKNTIIYGHNMKDGSMFADLRKYLDKDFLVAHPTFSYESGLTNYEVEIFAVYETTTDFYYIETEFPETTDFEDYLQKVKQQSVYTSNVKVSGKDRIITLSTCDTEKDYEKGRMVIQGKLVTK
What is the function of this protein?
Transpeptidase that anchors surface proteins to the cell wall (Probable) (PubMed:16247833, PubMed:19129190).  Recognizes and modifies its substrate by proteolytic cleavage of a C-terminal sorting signal.  Following cleavage, a covalent intermediate is formed via a thioester bond between the sortase and its substrate, which is then transferred and covalently attached to the cell wall (Probable).  Catalyzes a cell wall sorting reaction in which a surface protein with the consensus sorting signal NP(Q/K)(T/S)(N/G/S)(D/A) is cleaved between the fourth and fifth residues, and the fourth position is linked to the cell wall (Probable) (PubMed:19129190).  This is not the major sortase in Listeria, it seems to anchor only 2 proteins, Hbp2 (SvpA) and Hbp1 (PubMed:15028680, PubMed:16247833).
What are the official names of this protein?
Sortase B.
What is the protein family that this protein belongs to?
Belongs to the bacterial sortase family. Class B subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: EXD_DROPS
Sequence: MEDPNRMMAHTGGMMAPQGYSLSGQDDGQNTGNENEVRKQKDIGEILQQIMSISEQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACNEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKAAGASPYSMAGPPSGTTTPMMSPAPPQDSMGYTMGSGGYDQQQPYDNSMGGYDPNLHQDLSP
What is the function of this protein?
Transcription factor which acts with the selector homeodomain proteins altering the regulation of downstream target genes such as wingless (wg), teashirt (tsh) and decapentaplegic (dpp), thus affecting segmental identity.  Delimits the eye field and prevent inappropriate eye development.  Required for proper localization of chordotonal organs within the peripheral nervous system (By similarity).
What are the official names of this protein?
Homeobox protein extradenticle.
What is the protein family that this protein belongs to?
Belongs to the TALE/PBX homeobox family.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear translocation requires interaction with hth.
Protein: KNOS4_ORYSJ
Sequence: MEQQLPLLAPDSKAATSSPLCLTLDNPTSTSTSPAVPSSAPPPAAALEPSRQSFHERETDAIKAKIMSHPLYPALLRAFIDCQKVGAPPEVVGRLSALAGELDSRAEDRYLQGQSSDPELDEFMETYIDMLVSYRQELTRPIQEADQFFRNMEAQIDSFTLDDNGSEGGNSSEDEQEAGGGDMASAGLPEITSPCAEDKELKSHLLNKYSGYLSSLWRELSKKKKKGKLPRDARQKLLHWWQLHYRWPYPSELEKAALAESTGLDAKQINNWFINQRKRHWKPTPPAMEYRSLQPAGAASYGGASAGASTSGGGSAVVRGMEGQHFTGGGAYPRGDP
What are the official names of this protein?
Homeobox protein knotted-1-like 4, Homeobox protein OSH10.
What is the protein family that this protein belongs to?
Belongs to the TALE/KNOX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU2C_SYNPW
Sequence: MPEMGALLLTTPALAAPGELLNLSLNASAVAPEGAVLLAMLATLLVDLAGEKVSTRWVPPICYAGLGTALLLLALQWNAPLEPSFLGAFLPDHLAIAFRAVVALSTLLSLMISWRYAEQGGTPVGEYAGILLAATLGGMLLCGATDLVSVFVSLETLSVASYLLSGYMKRDARSSEAALKYLLVGSAAAAVFLYGSSLLYGLSGSTSLEAIGQALLSSPTPLAALALVFVLATVAFKIAAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALALRLLVGCFGSFDTQWKLLFTVLAVLSMTLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVCGTEDGFAAMVLYTAAYLFMNLGAFACIILFSIRTGSDRIADYAGLYQKDPLITLGLSLCLLSLGGIPPMLGFFGKIYLFFAGWADHQYVLVVVGLITSVISIYYYIGVIKMMVVKEPQEASDAVKAYPPVQWSTLGLPPLRVALVTCVVVTAVGGILSNPLFQWASDAVAGTPLLQQAIASVNGSSLG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SK1_SHELA
Sequence: EQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, SheLa-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLC11_MOUSE
Sequence: MQAAWLLGALVVPQLLSFGHGARGPGREWEGGWGGALEEERERESQMLKNLQEALGLPTGVGNEDNLAENPEDKEVWETTETQGEEEEEEITTAPSSSPNPFPSPSPTPEDTVTYILGRLASLDAGLHQLHVRLHVLDTRVVELTQGLRQLRDAASDTRDSVQALKEVQDRAEQEHGRLEGCLKGLRLGHKCFLLSRDFETQAAAQARCKARGGSLAQPADRQQMDALSRYLRAALAPYNWPVWLGVHDRRSEGLYLFENGQRVSFFAWHRAFSLESGAQPSAATHPLSPDQPNGGVLENCVAQASDDGSWWDHDCERRLYFVCEFPF
What is the function of this protein?
Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts.  Important for repair and maintenance of adult bone.
What are the official names of this protein?
C-type lectin domain family 11 member A, Lymphocyte secreted C-type lectin, Osteolectin, Stem cell growth factor.
What are the subcellular locations of this protein?
Cytoplasm. Secreted.
Protein: RBCR_THAPS
Sequence: MVLPFTLQQLRIFKAIASEKSFTQAAEILFVSQPSLSKQIKTLENRLGILLLNRTGNKILLTEAGVVFLQYSERILALCEESCRALNDLKDGERGNLKVGASQTIGAYLMPRVLTLFAQSYPQINLHIDIDSTRIIAKKVADRSLDIAVVGGDIPTGLKKNLEIEDFVEDELILIISKSHPFAKKKKKKISKEDLYHLNFITLNSNSTIHKFINNILIQNNIQTAQFNVIMELNSIEAIKTAVSLGLGAAFVSSSAIEKELELKTVEIITIENIRITRTLSIITNPDSHRSKAFDFFYNELWLLKNL
What is the function of this protein?
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
What are the official names of this protein?
Probable RuBisCO transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DAPB3_PSEMX
Sequence: MRHPAFRLTLLASTVAFALAPQAAQAAPSAADRIAGTELIARDALFGNPERANVQISPDGKYLSWVAAVDGVLNVWIAPADNPSQARAVTQDTARGIRSYFWSYQPDTLLYLRDSGGDEDFHLYAVDLKTGQAKDLTPFPKTTAQVAGVSPKHPGTILVGMNDRDAQWHDIYKVDLASGNRTLLEKNDAQIAGYIADADYTLKYAQRSRPDGGADVLRRGANGAWEKFDDIPFEDVLTTSPGGLTLDGKTLYFTDSRGRNTAALFAIDVASGKRTLVLEDARADVGGTLADPATGKVQAVSVDYLRDEWKVVDPAIRADLEKLEAIGPGDVSVNTRTLDDKTWIVAYSAAEAPLVYYRYDRSAGTLTKLFSARPKLEGKPLVPQWPVEIASRDNKTLVSYLTLPRSADANNDGKADAPVPLVLLVHGGPWARDSYGYGGYNQWLANRGYAVLSVNFRGSTGFGKDFTNAGNGEWAGKMHDDLIDAVQWAVKQGVTTQDQVAIMGGSYGGYATLTGLTFTPDAFACGVDIVGPSNLNTLLSTVPPYWASFFEQLAKRMGDPRTDAGKKWLTERSPLTRADQIKKPLLIGQGANDPRVKQAESDQIVKAMQAKNIPVTYVLFPDEGHGFARPENNKAFNAVTEGFLAQCLGGRAEPIGKDFTGSSISVPVGADGVPGLAEALKGHTQEVKK
What is the function of this protein?
Exopeptidase that catalyzes the removal of dipeptide units (NH2-P2-P1- or -P1'-P2'-COOH) from the free amino or carboxy termini.  Prefers substrates composed of bulky, hydrophobic amino acids at P1 and P1' positions.  Has endopeptidase activity on N-terminally blocked peptide derivatives which contain aromatic amino acid residue at the P1 position.  Exopeptidase activity is much higher than its endopeptidase activity.
What are the official names of this protein?
Dipeptidyl aminopeptidase BIII, DAP BIII.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
Protein: LEP_RICTY
Sequence: MNRDNTKTNKTVKQEFASFTFVICIALVIRILIMEPFTVPTGSMKATILENDYIFSTKYSYGYSNYSLSFFDFIPLFKGRVFAREPERGDIVVFRPPNDMSVRYIKRLIGLPGDKIQLIDDVIYINDKKIERTEVGTYIGEDGIKYLKFKETLPNGRTYFSYKLAPIFGIISNDRYSNTGVFYVPEGQYFFLGDNRDRSNDSRVNLGFVPFENFIGKAQFIWFSTKITWWDNDIGIINLILKLKPWIESVRLSRIFKNLYNVDE
What is the function of this protein?
Complements E. coli mutants temperature-sensitive for LepB function.
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: LRC42_BOVIN
Sequence: MSYYLNSENHLDSGPIYVRENGQLHMVNLALDDVRSSLQKPRPFRLFPKGFSVELCMNREDDTAQKEKTDHFIFTYTREGNLRYSAKSLFSLVLGFISDNVDHIDSLIGFPEQIAEKLFSAAEARQKFTEPGAGLRALQKFTEAYGSLVLCSLCLRNRYLVISEKLEEIKSFRELTCLDLSCCKLGDEHELLEHLTNEALSSVTQLRLKDNCLSDAGVRKMTAPVRVMKRGLENLSLLDLSCNPEITDAGIGYLFSFRKLNCLDISGTGLKDIKAVKHKLQTHIGLVHSKVPLKEFDHSNCKTEGWADQIVLQWERVTLEAMKPQETLESRTAAQHFYGKRARTEAPGKYPLTEAHMNSSEKLQFYKEKAADCHGPLLKHEALSSQESKKSKKRAFEEPEKEQGSSSQTSKQKYVCLAVEDWDLLNSY
What are the official names of this protein?
Leucine-rich repeat-containing protein 42.
What is the protein family that this protein belongs to?
Belongs to the LRRC42 family.
Protein: PTC1_DANRE
Sequence: MASDPRDPGPAGGVFGDLPPSYTRSPPPVNSDLLRRPSYCHAAFALKQISKGKAVGQKAPLWIRARFQAFLFSLGCHIQRHCGKVLFIGLLVFGALSVGLRVAAIETDIEKLWVEAGSRVSKELRYTKEKQGEESVFTSQMLIQTPKQEGTNILTQEALLLHLEAALSASKVQVSLYGKSWDLNKICFKSGVPIIENVMIERMIDKLFPCMIVTPLDCFWEGSKLQGGSAYLPGMPDIQWMNLDPLKLMEELSQFTSLEGFREMLDKAQVGHAYMNRPCLDPSDTDCPHSAPNKDPWQVPNIAAELQGGCHGFSKKFMHWQEELILGERVKDSQNALQSAEALQTMFLLMSPKQLYEHFKDDYEIHDINWNEDKATAILESWQRKFVEVVHGSIPQNSSSNVYAFSTTTLNDIMKSFSDVSVIRVAGGYLLMLAYACVTMLRWDCAKSQGAVGLAGVLLVALSVAAGLGLCSLLGLSFNAATTQVLPSLALGIGVDDMFLLGHSFTETRSNIPFKERTGDCLRRTGTSVALTSVNNMIAFFMAALVPIPALRAFSLQAAVVVVFNFAMALLIFPAILSLDLHRREDKRLDILCCFYSPCSSRVIQIQPQELSDANDNHQRAPATPTYTGSTITTSTHITTTVQAFTQCDAAGQHIVTILPPTSQISTTPPSMVLSTPTPTTDPYGSQVFTTSSSTRDLLAQVEEPKEGRECVPLPFFRWNLSSFAREKYAPLLLKPETKTVVVVVFVALLSLSLYGTTMVHDGLYLTDIVPRDTQEYEFITAQFKYFSFYNMYLVTMDGFDYARSQRQLLQLHNAFNSVKYVVKDGNHKLPRMWLHYFQDWLKGLQATFDADWEAGKITYDSYRNGTEDGALAYKPLIQTGSKKEPFNYSQLTSRRLVDGDGLIPPEVFYIYLTVWVSNDPLGYAASQANFYPHPREWIHDKYDTTGENLRIPAAEPLEFAQFPFYLNGLRQASDFIEAIESVRTICEEFMRQGIKNYPNGYPFLFWEQYIGLRHWFLLSISVVLACTFLVCAILLLNPWTAGVIVFILPMMTVELFGIMGLIGIKLSAIPVVILIASVGIGVEFTVHIALGFLTAIGDRNTRSAVAMEHMFAPVIDGAISTLLGVLMLAGSEFDFIMRYFFAVLAILTLLGILNGLVLLPVLLSLMGPPAEVVPANNANHLQSPSPEPMPPPMNHHGYYAGHIPKASHQAFSETSDSEY
What is the function of this protein?
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH).  Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity).
What are the official names of this protein?
Protein patched homolog 1, PTC1, Patched 1.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CRCB2_CORJK
Sequence: MNRLPPVALVFLGGALGAIIRWTLTVWIPALGDPTRVLGAATPLNIIGGIPLGDIALLVVNVLGALLLGLLVGMIPDSAHPRRTFWGTGVLGGFTSFSSLAAAVDATTDSASTILIGGTYGVFTLALGLIAAAMGLRLGRDLNELARLRRAADGADEPQDPHEPHKGGAR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREE_MICLC
Sequence: MIVTEILGNVHDDAGAALVGDRHREQVHLEGSALVKRIQRLRTDHGNEYGLRLPAGSPDLRDGDILTVDDDDEGERGNAVIVRVLSTDVLVISARSLREMAFVAHSLGNRHLPAQFFDADGPFGRDAMVVQHDHTVEDFLRAHDVPHERQERVMDVPFRHAEHTH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_SALHS
Sequence: MPESKYRQQTIRAPRGTVLTAKSWLTEAPLRMLMNNLDPDVAENPHELVVYGGIGRAARNWECYDAIVDALTRLEADETLLIQSGKPVGVFKTHDNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYNGTLAGRWVLTAGLGGMGGAQPLAATLAGACSLTIECQQSRIDFRLRTRYVDEQAATLDDALARITRYTREGKAVSVALCANAADILPELVNRGVRPDLVTDQTSAHDPLHGYLPSGWRWEEYQKNAQSDPHGTMQAAKRSMAAHVRAMLAFSQMGVPTFDYGNNIRQMAKEMGVENAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIVAEDKHLHHWLDMARERIHFQGLPARICWVGLEWRQKLGLAFNEMVRCGEVSAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCDGTDEAAARIRRVLHNDPATGVMRHADAGYDLAVECAVEQGLNLPMVAATQGKG
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_CERS5
Sequence: MAGRSGRTFPRVAVLMGGTSSEREVSLSSGHSCSAALRDAGYEVTEVDAGPDLARVLAEVQPDAVFNALHGRWGEDGCVQGLLEWLRIPYTHSGVLASALAMDKARAKEVFAAAGLPVTQSVIATPDEVQAGHVLPPPYVVKPNCEGSSVGVYIVQADANGPPRLAPDMPRDLMVETYIPGRELTVTVMGDRALAVTDIVTDGWYDYDAKYRPGGSRHVVPAELPAEITDACLDIALRAHRALGCRGISRSDLRWDESRGAEGLILLETNTQPGMTPTSLSPEQAAHCGLSFPEFCAWMVEDASCNR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPYL3_RAT
Sequence: MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVMPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLSKEKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDAVKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSTRGSPTRPNPPVRNLHQSGFSLSGTQVDEGVRSASKRIVAPPGGRSNITSLS
What is the function of this protein?
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.  Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
What are the official names of this protein?
Dihydropyrimidinase-related protein 3, DRP-3, Collapsin response mediator protein 4, CRMP-4, TOAD-64/Ulip/CRMP, TUC-4b.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, growth cone. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
Protein: TAL_LEPCP
Sequence: MNQLDQLKRLTTVVADTGNFLQLAQFAPQDATTNPSLILKAVQQAEYAPLLTETVARHRGLPLDQVVDQVLVRFGLEILKIVPGRVSTEVDARLSFDTAATVARAHRIINLYDDAGIGRERVLIKIASTWEGIQAAAELEREGIHCNLTLLFAFAQAVACGAAGVQLISPFVGRIYDWYKKSAGANWDEAAMAGANDPGVKSVAQIYSYYKKFGIATEVMGASFRNVGQITALAGCDLLTISPDLLAQLQASEEPISAALDAAAARDAAIDAVRYDEPGFRFALNEDAMATEKLAEGIRAFAADAAKLDKMILAL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETD_PORPU
Sequence: MSILKKPDLTDPKLRAKLAKGMGHNYYGEPAWPNDLLYVFPVVILGTIACSIGLAILEPSSLGEKSNPFATPLEILPEWYFFPTFNLLRVIPNKLLGVLSMAAVPAGLLTVPFIENVNKFQNPFRRPIATTIFLISTVITIWLGIGATMPINNAITLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.