PharMolix/UniProtQA huggingface dataset:
Protein: RLMI_ECOLC
Sequence: MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVDHQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFSRRLQQAQKWRDWLAQKDGLDSYRLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECSIYDRSDVAVRKKEGMELTQGPVTGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRYVENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFVRDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_COXBN
Sequence: MLKAPRFWYQPRSLLGGILSPFSFLYQIIVRIRRGLYAVGLKKISKFPVPIVIVGNITVGGSGKTPFVIWLANELKNRGFRPGVVSRGYGGKANRFPQTVTENSDPLQVGDEAVLLMKKIDCPMVVCRDRGAAVKHLLRNFQCDVVIGDDGLQHYSLGRDLEIALLDDRHLGNGRCLPAGPLREPKSRLNTVDFVVPKQLRPNEIYQLKNPAKKIDFNELKELTVHAVAGIGNPGYFFKQLETLGANVIAHPFRDHYFYRSEDFNFDDDHLIILTEKDAIKCKQFDDERLFCFSVDAVVPDQFQNDFFRLISNIILRKQAQREGI
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: TXIP1_HUMAN
Sequence: MGGHLSPWPTYTSGQTILQNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSGLLREKDFFPGLGYGEAIPAFLRFDGLVENKKPSKKDVVNLLKDAWKERLAEEQKETFPDFFFNFLEHRFGPSDAMAWAYTIFENIKIFHSNEVMSQFYAVLMGKRSENVYVTQKETVAQLLKEMTNADSQNEGLLTMEQFNTVLKSTFPLKTEEQIQELMEAGGWHPSSSNADLLNYRSLFMEDEEGQSEPFVQKLWEQYMDEKDEYLQQLKQELGIELHEEVTLPKLRGGLMTIDPSLDKQTVNTYMSQAFQLPESEMPEEGDEKEEAVVEILQTALERLQVIDIRRVGPREPEPAS
What is the function of this protein?
Possible role in spermatogenesis.
What are the official names of this protein?
Translin-associated factor X-interacting protein 1, Trax-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: DB127_PANTR
Sequence: MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEACKKITKPSHPKPATLALTLQDYVTIIENFPSLKTQST
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 127, Defensin, beta 127.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TEG7_SUHVK
Sequence: MLGGIFSGWCGRRGRGRAYEPPDELRLRESLAVLNVILPAPLAAEDVMASAEAARRLARADTLARTYQACQRNLECLARHEASGDDGLDAVVAAHAANARRLADTCLAALMHLYLSVGAVDADTDDLVEQALRMTAESNVVMSDVAVLERTLGLARRRQPAPVRAAPAGLGLPVPAQPAPRATAARPAPPPPPEEAGEDEEGDRPEDDAAPLLPPRAPAKTRPPEKARRLAEACKM
What is the function of this protein?
Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes.
What are the official names of this protein?
Tegument protein UL51.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL51 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein: CC150_HUMAN
Sequence: MDCKVHMETTVSRPVLSPTHINATASETFTVLQQRMRIVEEQTSSLRDDLIMLDFGEKRGYLEAPDCLEDLDSQKVISPIQNEAICAGKTDILWKNCEFLVNRMCRLESLMQSLKMNIFRLQTEKDLNPQKTAFLKDRLNAIQEEHSKDLKLLHLEVMNLRQQLRAVKEEEDKAQDEVQRLTATLKIASQTKKNAAIIEEELKTTKRKMNLKIQELRRQLAQEKYLRESLEKSASAMLLKIQEMGSTVEVERKQVHILQQNCIALRDSIQSAQELLAQEQKKKEELEIATSQLKSDLTSRDDLISKLVEENKNLQISFNKEHEENAYLRSEIMSLHEASEKAQVLNDQLTKKCSELSCMLQTVTMEKARIIADHQAILQVEQKMMTQTFQEQNLLLDAAHASITNELQTVQNEKTQLQAHLDHLILEHNQCIQKAQDAEKRTAVQKELLESTIARLRGELEASMQEKKSLLEEKERFQREVNKTEKEIVQERCNLEKELAKNKVDINTLTHNLQTLEEENKHLADQMASLELQQVTSDYHGLAQQKVEKITESKNKLAYENGKLQIKVKQLEEQVQSFTDTSLQNDHLRKMNKYLQTKYAQANSELSAKRVHLQQADAHLKEVKSILERSKEELSRTVKCRNAALKESQKLKEDLEAVEDRENKKVGNFQRQLAEAKEDNCKVTIMLENVLASHSKMQGALEKVQIELGRRDSEIAGLKKERDLNQQRVQKLEAEVDQWQARMLVMEDQHNSEIESLQKALGVAREDNRKLAMSLEQALQTNNHLQTKLDHIQEQLESKELERQNLETFKDRMTEESKVEAELHAERIEALRKQFQTERETTKKVAQREVAELKKALDEANFRSVEVSRTNRELRQKLAELEKILESNKEKIKNQKTQIKLHLSAKANNAQNIERMKQIEKELKQMELIKDQYQKKNYEQSLSIQRFVCEMTNLQKEMQMLAKSQYDASVRNKQQELHLEAERKIRQELENRCQELEETVRHLKKCKEATENTLKEASVESEQITANLEEAHRWFKHRFDGLQLELTKNRLQRPSGEDRWQEKDQDVKHDVMSNQSVLHRWERKQNLRPMPKKYHSEVQRK
What are the official names of this protein?
Coiled-coil domain-containing protein 150.
Protein: RS12_BURO1
Sequence: MPTINQLVRKGRQSETTKSKSPALQDCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHMVRGSLDTQGVKDRKQARSKYGAKRAKAAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RS18_PEDPA
Sequence: MAFQKRGGRRRRKVDYIAANHIEYIDYKDTELLKRFISERGKILPRRVSGTSAKNQRRLTIAIKRARIMGLLPFVAED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PANB_ECOLC
Sequence: MKPTTISLLQKYKQEKKRFATITAYDYSFAKLFADEGLNVMLVGDSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_ECOLI
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Represses transcription of the class Ib RNR genes nrdHIEF but has much smaller effect on transcription of the class Ia RNR genes nrdAB and class III RNR genes nrdDG.  By binding to nrdR boxes in the promoter regions to alter promoter activity, nrdR differentially regulates nrdAB, nrdHIEF and nrdD transcription in aerobic growth.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RM23_DROME
Sequence: MSTRWYPIYQRGNPQLRVFLPNFWMKLIRPTEEQPPNVVTFSVSMEMTKYDVRNYLEKIYKLPVVDVRTRIAMGETKKDQTYGYITKKDDVKLAYVTLPREESFVFPDFFSEKAEKQAKEEKSLDESKAGFRRFLDRNKKRPGTPGWFSI
What are the official names of this protein?
39S ribosomal protein L23, mitochondrial, L23mt, MRP-L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FBID_MYCS2
Sequence: MSGRRTPGAASDGSAGGQAAVIIAVKRLTAAKTRLAPIFSAATREEVVLAMLVDTITAASTVAPVTVVTPDEVAADAARQLGAGVLADPTPEGHHNPLNNAIMAAEEHLRAGTPNIVVLQGDLPAMQPRELAEALAAARTYPRSFVGDRHGTGTSALFAFGVPLQPRFGADSATHHRHSGAIELTGAWPGLRCDIDTAEDLRTARRLGVGPATAQAIAAHR
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase, 2-phospho-L-lactate guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: DPO4_SALPA
Sequence: MRKIIHIDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGAISTANYPARQFGVRSAMPTAMALKLCPHLTLLPGRFDAYKEASRHVRDIFSRYTSLIEPLSLDEAWLDVTDSPHCYGSATLIAREIRQTIFNELQLTASAGVAPVKFLAKIASDLNKPNGQYVITPADVPGFLKTLPLAKIPGVGKVSAAKLENMGLRTCGDIQQCDLAMLLKRFGKFGRVLWERSQGIDERDVNSERLRKSVGVERTLAEDIHEWSDCEAIIEHLYPELERRLAIVKPDLLIARQGVKLKFNDFQQTTQEHVWPQLNKEDLITTARKTWDERRGERGVRLVGLHVTLLDPQLERQLVLGL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB5_BOVIN
Sequence: MAEESSKAVKYYTLEEIQKHNNSKSTWLILHYKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDARELSKTFIIGELHPDDRSKITKPSESIITTIDSNPSWWTNWLIPAISALFVALIYHLYTSEN
What is the function of this protein?
Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.
What are the official names of this protein?
Cytochrome b5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: RS20_THET2
Sequence: MAQKKPKRNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAVQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS2_ORYSJ
Sequence: MQPPPMRERQRWRPEEDAILLAYVRQYGPREWSLVSQRMNRPLHRDAKSCLERWKNYLRPGIKKGSLTDDEQRLVIRLQAKHGNKWKKIAAEVPGRTAKRLGKWWEVFKEKQQRELRDRDRRRLPPPLDGDERGCAGGRYDWLLEDFADKLVNDHHRRMMAAPILPPWMSSSPSSSSSPSVTLSLASAAVAPAPAAPPPTWGGGGGGEVVVAELMECCREMEEGQRAWAAHRKEAAWRMKRVEMQLETERACRRREATEEFEAKMRALREEQAAAVERVEAEYREKMAGLRRDAEAKEQKMAEQWAAKHARLAKFLDQVAACRRWPPVEINGGGGGGPGGGR
What is the function of this protein?
Transcription factor required for normal cell differentiation.  May interact with other proteins to repress the knox homeobox genes (By similarity).
What are the official names of this protein?
Protein rough sheath 2 homolog, OsPHAN, OsRS2, Protein PHANTASTICA homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: MAK5_AJECN
Sequence: MAKKRARVAQDLSHKSKKRQRVEATGDDGEIVGIDQLDWKEVALPDRLEDAEGFFGLEEIDGVDLVRPIGNGEIKFKAARNRVKKNVANSISSNTEHEAGEWSGISDDEEPADDRVHSSKGKQTNVDKIETKEDKEKKSKKQSKKDLKLIDAEIQRKKKPAPKHDIQSGISFEALEEEVDGDEVDVSGWDPLGISAEIQTSLSKLRFAKPTPIQTACIPLIASGHDVVGKASTGSGKTLAFGIPILEYYLKNRREEPVQHNDAELSSKYPIALILSPTRELAHQLSKHITALCTNAPNINARIALLTGGLSVQKQQRVLANADIVIGTPGRLWDVISTGHGLLRKFQNIKFLVIDEADRLLSEGHFKEVEEILTALDRKEIHHKVTADSESEDDASRESPRQTLVFSATFHKGLQQKLAGKGRYFDGDLLDDKQSMEYLLKKLNFREDRPKFIDVNPVAQMAENLKEGLVECPAMEKDLYLYTLMLYHPQHRTLVFTNSISAVRRLTAFLQNLNLPALALHSSMAQKARLRSVERFSSPTADPSSILVATDVAARGLDIKGIDLIIHYHVPRTADTYVHRSGRTARASASGKSILLCAPEEIVGVARLAAKVHASSTASSSSSSSVTKRLPLHSVDLDRRVIARVRPRVALAKKITNHALAKEKLSSENDWLRSAADDLGVDYDSEEFAEQAKGKGRGRGRGGGREAREKAAGSMTKAEVATLKAQLRELLGKRINMGVSERYLTAGRVDIEALLAVGGNKTFLGQVGELDF
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase MAK5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CEMA_GOSHI
Sequence: MAKKKAFTPLLYLASIVFLPWWISLSFNKSLKSWITNWWDTRQSETFLNDIQEKSILEQFIEVEELFLLDEMIKEYPETHLQKLRIGIQKETIQLIKLHNEDHIHTILHFSTNLICFVILSGYSILGNEELLILNSWVQEFLYNLSDTIKAFSILLLTDLCIGFHSPHGWELMIGSIYKDFGFAHNDQIISGLVSTFPVILDTIFKYWIFRYLNRVSPSLVVIYHSMND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: TRMD_LACCB
Sequence: MQIDVLSLFPNMFEPLRESMIGKAIERELLNFDVVDYRSYSHDKHHHVDDTPYGGGAGMLLKPEPLFEAMDGVNERHPGPKRVILMDPAGKKFNHQAARALSQEDHLVFICGHYEGYDERIRTLVTDEYSLGDYVLTGGELPAMVMIDAIVRLLPGVLGNDESAHTDSFENGLLEYPQYTRPPEYRGMKVPEVLQNGNHQLIARWRQKESLRRTYLRRPDLLKTITLDQTAQKLLREVKTEEATKAAEARLKNQS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_ROSS1
Sequence: MSSEDTTSQRAPRNWWGPFAPIGEALRFLTILPVPGLPPMSEEAIPQSIRYFPIAGLVIGGILAAVGWGAGVLWNETVRAVVLVVAWGVLTAGMHLDGLSDTFDGVMSWRSRERKLEIMRDSRIGVMGALALAAVLGLKAAFLAGAGDAWLTAVVLAPVLGRWADVYGIVRFPPAREGGLGRTFQSYLRPGDFAGASVATLALALIVGGVGGLIALALVWMVTHLLGRWWTRDLGGLTGDTYGALCEIAEVVALATLTLSAPMRLLAT
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEU1_SHIBS
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: KCY_SALNS
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDLASEDALVPLASHLDVRFVSTDGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFREAPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQENGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTRLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_PSEFS
Sequence: MSKQPSLSYKDAGVDIDAGEALVERIKSVAKRTARPEVMGGLGGFGALCEIPAGYKQPVLVSGTDGVGTKLRLALNLNKHDTIGIDLVAMCVNDLVVCGAEPLFFLDYYATGKLNVDTAAQVVTGIGAGCELSGCSLVGGETAEMPGMYEGEDYDLAGFCVGVVEKAEIIDGSKVAAGDALLALPSSGPHSNGYSLIRKIIEVSGADIENTQLDGKPLTDLLMAPTRIYVKPLLKLIKDTGAVKAMAHITGGGLLDNIPRVLPKGAQAIVDVASWQRPAVFDWLQEKGNVDETEMHRVLNCGVGMVICVAQEHVETALNVLREAGEQPWVIGQIATAPEGAAQVELKNLKAH
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANM7_BOVIN
Sequence: MKVFCGRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNMKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNGFSDKIKVINKHSTEVTVGPDGDMPCRANILITELFDTELIGEGALPSYEHAHRHLVQANCEAVPHRATVYAQLVESRRMWSWNKLFPIRVQTSRGERVIIPPLELERCPGAPSVCDIQLNQVSPADFTILSDVLPMFSVDFSKQVSSSAACHSRQFEPLVSGRAQVVLSWWDIEMDPEGKIKCTMAPSWAHSDPEELQWRDHWMQCVYFLPQEEPVVQGLALCLVAYHDDYCVWYSLQKTSPEKNGRVHPVRPVCDCQAHLLWNRPRFGEINDRNRTDQYIQALRTVLKPDSVCLCVSDGSLLSMLAYHLGVEQVFTIENSAVSHRLMKKIFKANHLEDKINIIEKRPELLTPADLEGKKVSLLLGEPFFTTSLLPWHNLYFWYVRTAVDQHLGPGAVVMPQAASLHVVVVEFRDLWRIRSPCGDCEGFDVHIMDDMIKRALDFRESKEAEPHPLWEYPCSSLSEPQQILTFDFRQPVPLQPIHAEGTIELRRCGRSHGAVLWMEYHLTADSTVSTGLLKSAEDEGDCCWNPHCKQAVYFFNTTLDPRAPPGSSQTVTYTVEFHPHTGDITMDFTLSDALDSGC
What is the function of this protein?
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA.  Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles.  Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s.  Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites.  May also play a role in embryonic stem cell (ESC) pluripotency.  Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
What are the official names of this protein?
Protein arginine N-methyltransferase 7, Histone-arginine N-methyltransferase PRMT7, [Myelin basic protein]-arginine N-methyltransferase PRMT7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: PME43_ARATH
Sequence: MNKYVLLGVTALIMAMVICVEANDGNSPSRKMEEVHRESKLMITKTTVSIICASTDYKQDCTTSLATVRSPDPRNLIRSAFDLAIISIRSGIDRGMIDLKSRADADMHTREALNTCRELMDDAIDDLRKTRDKFRGFLFTRLSDFVEDLCVWLSGSITYQQTCIDGFEGIDSEAAVMMERVMRKGQHLTSNGLAIAANLDKLLKAFRIPFPFLRSRRGRLGILGSGSSRDESVGSSQDSPPNEDSSDDSPSTVDSSENQPVDSSSENQSSDSSNNRPLDSSKNQQMESSEDTPKKSAFSGNQPLDDSSDKLPQKSTSSENQPLDSSENPPQKSTSSENRPLDPLRKLNPLNKLDSLKDRHLSEEGEFPPWVTPHSRRLLARRPRNNGIKANVVVAKDGSGKCKTIAQALAMVPMKNTKKFVIHIKEGVYKEKVEVTKKMLHVMFVGDGPTKTVITGDIAFLPDQVGTYRTASVAVNGDYFMAKDIGFENTAGAARHQAVALRVSADFAVFFNCHMNGYQDTLYVHTHRQFYRNCRVSGTIDFVFGDAKAVFQNCEFVIRRPMEHQQCIVTAQGRKDRRETTGIVIHNSRITGDASYLPVKAKNRAFLGRPWKEFSRTIIMNTEIDDVIDPEGWLKWNETFALNTLFYTEYRNRGRGSGQGRRVRWRGIKRISDRAAREFAPGNFLRGNTWIPQTRIPYNAN
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Putative pectinesterase/pectinesterase inhibitor 43.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: JPH1_MOUSE
Sequence: MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHEAAAAAADSPAGTRGGFVLNFHADTELGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYIKQRCQEGGDIKENPEEKVLEKPPSPKESPHFYRKGTTPPRSPESSPKQSHSPQPSSPEPSKKQNPSPGARLSQDKQSLAEEQVTAFVNKPSMSKAPAKELGASVSKYSGRHHVPNPSNGELHSQYHGYYVKLNTPQHPPEDREDDRGVSQSSSALVPRPSPNKWGPPKSVTKPVAKESKTEPKAKKSELAIPKNPASNDTCPSLEKEANSGPNSIMIVLVMLLNIGLAILFVHFLT
What is the function of this protein?
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells.  Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.  JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.
What are the official names of this protein?
Junctophilin-1, JP-1, Junctophilin type 1.
What is the protein family that this protein belongs to?
Belongs to the junctophilin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Sarcoplasmic reticulum membrane; Single-pass type IV membrane protein. Note=Predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic/sarcoplasmic reticulum membrane, while the N- terminal part associates with the plasma membrane. In skeletal muscle cells, it is predominantly localized at the junction of the A and I bands.
Protein: RRF_CLOBM
Sequence: MIKEILKKADEKMGKSIVALKRELASMKAGRANPAMLDRIDAEYYGSMTPLNQLANISVPEARVLLIQPWDKSSMGAIEKAILKSDLGLNPSNDGTVIRLVIPELTEETRKNIVKTVKKTGEETKVAIRSIRRDCNDDVKNLKKDDVSEDDIKKTEDDIQKKTDKYIKEIDSIISAKEKEILSI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.