PharMolix/UniProtQA huggingface dataset:
Protein: BIOW_METIM
Sequence: MRASREGKHISGGERLVSEEKIEEAVLELLRKALTHENGKPDFINIKIEKIDKVNYIKALPIKTITCKNKKEAREVAKKILLEEGIPEEVVEKAFKIIDKGGMRGAAILNLNGERLEPDRERGVRVKNIDTSERLKEKILKEGLGTERTVDAIAIASKVIRLGIIAELCTSDNKSYTTGYVATKKGYFRITNLKNINEPGGRVFFVKDIDEELIKRLEEEAYIIDL
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.
Protein: DEN1A_XENLA
Sequence: MGSRLKQNPDTTFEVYIEVNRPGSTDEDPELQRIFPEDFSDQEVLQTVTKFCFPFSLDSLTSSHVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEAFYKLLNILAEYSSKNQDSQRNELLKTLHGHPIPEPGTPMHLSVHSHFTVPDSQELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILICCSKLSTLTACIHGSSAMLFPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHSSLMEKVKGMSLDDVVFLNVDTNTLETPFDDLQNLPNEVVSALKNRIRKMSTTTGDGVARAFLKAQASLFGSYRNALKIEPEEPITFCEETFVSHRSSGLRPFLQNAIQLQLFKQFIDGRLDLLNSGNGFSDVFEEEINMGEYAGSDKLYHQWLSTVKKGSGAFINTMKTRANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDMAENGFSTATEEPLPQISPSSIEKKRGEERRPITVHFGQVRPPRPHVPRRPKSNAVVESRTTAGSSPDQPQQYRTLKESDADGDEAISPEKDSSEATVKEPQSTEVKHVSLLEDIFSNLQTEPPLLSQAKSLEDLRTPKEDHENQFTFDYQRMDLTAQERTRTIPAMKHGHPYNKLWSMGHDDMAIPNKYLQISPERHLTLPSNSTVTPHKDSALTNIEKEVTIASSQGNITIPRPHGRKTPELGIVPPPPAPRGIKLQTAMTDANKQQTGDSSNYHGQITEGSLRELSADNGEKETAGSSTSEILKPVKVSTEVGMNDDDLLSLLDPLKAGRYQTASQPPMGTLPHSFETPCCSSTPLLTSLQSDFVSPAFSHQLGFAPQPAFLHSPLNPFAQALAAEKTASVMGPPMGVFKAPVATALGSHSFLPTPGIYHSPRPLTSALQGSNLFGQISSGTPLNPVIRQSHSLSETQSNMPLMTSIPAGHRTLPMVQSRSKHQDGKPREYPPIPPRPAKLLEPALLPTKSDQPIDPFEDLLNKTKQTVTPASGKVEHLRKQWETFE
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form.  Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes.  Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P.
What are the official names of this protein?
DENN domain-containing protein 1A, Connecdenn.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Presynaptic cell membrane. Note=Associates to membranes via lipid- binding activity.
Protein: NU2C2_LOLPR
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFNGSFIFPECILIFGLILLLMIDSTSDQKDRPWFYFISSTSLVISITALLFRWREEPIISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFILTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKRDLRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALISITVGLGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRILDIPFYFSSNEWHLLLEILAILSMILGNLLAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVLSIYYYLKIIKLLMTGRNQEITPYVRNYRRSPLRSNNSIELSMTVCVIASTLPGISMNPILAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL28_CHLTA
Sequence: MSKKCALTGRKPRRGYSYAIRGISKKKKGIGLKVTGRTKRRFFPNIMTKRLWSTEENRFLKLKISAAALRLVDKLGLDQVVARAKSKGF
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DX39B_PONAB
Sequence: MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
What is the function of this protein?
Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint.  Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity.  Even with the stimulation of RNA, the ATPase activity is weak.  Can only hydrolyze ATP but not other NTPs.  The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA.  However, ssRNA stimulates the ATPase activity much more strongly than dsRNA.  Can unwind 5' or 3' overhangs or blunt end RNA duplexes in vitro.  The ATPase and helicase activities are not influenced by U2AF2; the effect of ALYREF/THOC4 is reported conflictingly with [] reporting a stimulatory effect.
What are the official names of this protein?
Spliceosome RNA helicase DDX39B, 56 kDa U2AF65-associated protein, DEAD box protein UAP56.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1.
Protein: ACEK_RHOPT
Sequence: MTATASHTRARPLGASEIEHATRIAEPDFDLLDALYRTDDPDDQARLLARVVLSAFDNYYAVSRRIPALAQAAFEARDWPVTVRLSKIRIGLYTACIDQLVPLLKAGLPELTTDEQLWPTAEAELLAAIEGRYEADFAFAFWQSLRRKLVSDEWRPVSYDAGSTARRTTSPAAVLKTTTTTLPITAEVIAGILGDAGFRVPWRDRDGDAALAAQAIETALEPLSPRPGEPVKIEIADAGFFRNRGACLVGRIQLRDRGDMPMRNLPLLIALLNEKDGLVVDAVLTDSDELQYAFSSTLANYHATNPRYHELARLLYELMPKRPLGTQYSCIGFHHLGKVAVMSEILAEHRKTKERLATAPGFKGTVAIAFTMPSSAYVLKIIRDHPTDDYKFDYFDGLDEVLRKYNLVHEIDRAGSMLDNIIYSNVKLDRAMFAPELLDELLEAGIGTVTLDRGALVFRHLIVQIKLTPLPLYLANASAAESRAAVINLGDCIKNNAAADIFNKDLDGRNYGVSRIRKVYLFDYDAVEPLTSVTVSRDGAAPGEFDNGMVFRPQEMLEGLRIDDPGLRRAFRDAHPELMQADYWEGMQRALRDGKVPKVMNYPASRRLQR
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B915_XENLA
Sequence: MKEEIAATVVFLTMLVKKHKQLSKQKIEKFAAKLTTLLFAKYKTHWYAENPTKGQAFRCIRINECQALDAVLEKACTESNVDFNELGLPKEMTIWVDPFEVCCRYGEKNDPFTIASFKGKDGYNAPKRISNAVEKATSDYHSGTSSDEEPTNKEPKTIPKVSNPNSIYQCADYTQAIPSWSQYPRRKNYQNDGYPHQPMPYYPQQKPYKAFRRSASTFSGPRVDRYHWVNMKR
What are the official names of this protein?
Maternal B9.15 protein, p30 B9.15.
What is the protein family that this protein belongs to?
Belongs to the BTG family.
Protein: RS11_STRPF
Sequence: MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DNAA_LACCB
Sequence: MPNLEELWAYLNDKFREELTPVGYSTWIQTAKPVKLTKDKLEIEVPASLHKAYWEKNLVTKVVEGVYEFAQLEVDPVIMTKDELQPAPATDQRPAVEEDDQNLTFKAKTHLNPKYTFDRFVIGKGNQMAHAAALAVAEAPGTTYNPLFIYGGVGLGKTHLMQAIGNLVLDNNPAANIKYVTSENFANDFINSIQTKQQEQFRQEYRNVDLLLVDDIQFFGDKEATQEEFFHTFNTLYENMKQIVLTSDRLPNEIPKLQERLVSRFNKGLSVDVTPPDLETRIAILRNKADAEDLSIPDDTLSYIAGQIESNVRDLEGALVRVQAFSTMKNEDITTSLAADALKALKLDDRSGQLTIPQILNAVAKYFQLTVQDLKGKKRVKQIVIPRQIAMYLAREMTDNSLPKIGQEIGGKDHTTVIHAHEKIMASMTTDENLKAQVIELRNILKNRG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_FRAAA
Sequence: MSAERTLILVKPDGVSRGLVGEVVGRLERKGLTLVALELRTLERSVAETHYGEHASKPFFGELVDFIVSGPLVALVAEGPRAVEASRGLIGATDPVKAAPGSLRGDYALEIGQNLVHGSDSPESAKREIDLFFPGLS
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOC4L_DANRE
Sequence: MAPSGDSNVKEHNNQVSYKKAINTKTDLILQNKKHANDIFDVIEYLQSEKEKEIIFATNACSKIFCELIERGDLFVGELPKEEDLAQGDRSAEEKYHIFMRHRYNSCVELMLENVSHESFQVKETSLCAVMKFVATEGKHPLQNLDWSEHYNFPRELIQALVEHLLSEKEDMSLLISRFQEFMEKDDVRYYVMSSVRYSTATVMERNKKAVIPVFQNNVFNLLTTINIPNQASEMTNFLVQQQSKHDDWKAAKLKEHKRAFEQMWLLFLRYKLPGSMYKKILVILHESILPQMSDPKLMMDFLSAAYDIGGAISLSALNGLFVPIHEHNLDYPDFYKKLYNLLDPSIFHVKYRARFFHLANIFLSSTHLPVYLVAAFVKRLARLSLTAPPTALLILLPFICNLIRRHPSCRVLIHRPSAADEPCDDPYVMEEEDPAQCHALESSLWEIKTLQNHHHPDVSKAATMINEPLSAQEEDISELLELTTFELMERELKGEKKTVPLEFDMATDLLKSSREVLGVHFTLE
What are the official names of this protein?
Nucleolar complex protein 4 homolog, NOC4 protein homolog, NOC4-like protein, Nucleolar complex-associated protein 4-like protein.
What is the protein family that this protein belongs to?
Belongs to the CBF/MAK21 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Nucleus, nucleolus.
Protein: LEUC_STAAB
Sequence: MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGLRLQNRKLRRPDLTFATLDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGIIQPDDITFEYVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEMGVNFSEPFPEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVKGNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWREPGCSMCLGMNPDQVPEGVHCASTSNRNFEGRQGKGARTHLVSPAMAAAAAIHGKFVDVRKVVV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RLP8X_ARATH
Sequence: MKTNFVILLLLLCVFAISPSQQEEINQHNPGIYHQKLLYKVQQWRTSLKESNSVELKLSLAAIVAGVLYFLAALISSACGIGSGGLFIPITTLVSRLDLKTGKRFLGQYLIWVILLLGQLHECKSCIEKERVALLDFKKYWMSITQESDLDYVFPTWNNDTKSDCCQWESIMCNPTSGRLIRLHVGASNLKENSLLNISLLHPFEEVRSLELSAGLNGFVDNVEGYKSLRKLKNLEILDLSYNNRFNNNILPFINAATSLTSLSLQNNSMEGPFPFEEIKDLTNLKLLDLSRNILKGPMQGLTHLKKLKALDLSNNVFSSIMELQVVCEMKNLWELDLRENKFVGQLPLCLGRLNKLRVLDLSSNQLNGNLPSTFNRLESLEYLSLLDNNFTGFFSFDPLANLTKLKVFKLSSTSDMLQIKTESEPKYQFQLSVVVIRVCSLEKIPSFLLQDNLFTIFQMPATIVHELQFLDFSVNDISGLLPDNIGYALPNLLRMNGSRNGFQGHLPSSMGEMVNITSLDLSYNNFSGKLPRRFVTGCFSLKHLKLSHNNFSGHFLPRETSFTSLEELRVDSNSFTGKIGVGLLSSNTTLSVLDMSNNFLTGDIPSWMSNLSGLTILSISNNFLEGTIPPSLLAIGFLSLIDLSGNLLSGSLPSRVGGEFGIKLFLHDNMLTGPIPDTLLEKVQILDLRYNQLSGSIPQFVNTESIYILLMKGNNLTGSMSRQLCDLRNIRLLDLSDNKLNGFIPSCLYNLSFGPEDTNSYVGTAITKITPFKFYESTFVVEDFVVISSSFQEIEIKFSMKRRYDSYFGATEFNNDVLDYMYGMDLSSNELSGVIPAELGSLSKLRVMNLSCNFLSSSIPSSFSNLKDIESLDLSHNMLQGSIPQQLTNLSSLVVFDVSYNNLSGIIPQGRQFNTFDEKSYLGNPLLCGPPTNRSCDAKKTSDESENGGEEEDDEAPVDMLAFYFSSASTYVTTLIGIFILMCFDCPLRRAWLRIVDASIASVKSMLP
What are the official names of this protein?
Putative receptor-like protein 8, AtRLP8.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ATPA_CORGL
Sequence: MAELTISSDEIRSAIANYTSSYSAEASREEVGVVISAADGIAQVSGLPSVMANELLEFPGGVIGVAQNLEADRVGVVVLGNYELLKEGDQVRRTGDVLSIPVGEAFLGRVINPLGQPIDGLGEIASEEDRVLELQAPTVLERQPVEEPLATGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQKANWETGDKTKQVRCIYVAIGQKGSTIAALRKTLEEQGALEYTTIVAAPASDAAGFKWLAPFAGAALAQHWMYQGNHVLVIYDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDELGAGSITALPIIETKANDVSAFIPTNVISITDGQVFLESDLFNRGVRPAINVGVSVSRVGGAAQTKGMKKVAGSLRLDLAAFRDLEAFATFASDLDAASKSQLERGQRLVQLLIQSENAPQAVEYQIISLWLAGEGAFDNVPVEDVRRFESELHEYLGSNAAQVYEQIAGGAQLSDESKETLLKATEDFKSAFQTTDGTPVINEPEVEALDAGQVKKDQLTVSRKVSKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: COBT_YERE8
Sequence: MQTLSSILRTIAPLDSKAMARATTRLDGLLKPQGSLGRLEQLAIQLAGMRGLYGHQVDRKQIIVMAADHGVYDEGVAISPRVVTMVQALNMVRGVTGVCVLAANAGAEVKIVDVGIDSDTLPGVIDMKVARGSGNIARGAAMTRQQAEDLLIASATLTLQQAAGGVKVFGVGELGMANTTPAAAMVSVFTDSDPELAVGIGANFPSEQLHHKVAVVRRAIETNQPDASDGIDVLAKVGGFDLVGMTGVMLGAAAAGLPVVLDGFLSYASALAACRIEAKVRDYLIPSHLSAEKGAVIALNHLQLEPYLQMGMRLGEGSGAALAMHLVDAACAMYNNMGSLAESNIELPGCVN
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: RL19_CITK8
Sequence: MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSIAVKRRGAVRKAKLYYLRERTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PABP_CANGA
Sequence: MADITEKTAEQLENLSLQDKQEGTNEENQSETVSASLYVGDLDPSVSEAHLYDIFSPIGAVSSIRVCRDAITKTSLGYAYVNFNDHDAAKTAIEKLNFTPIKGKLCRIMWSQRDPSLRKKGAGNIFIKNLHPDIDNKALYDTFSVFGNILSSKVATDETGKSKGFGYVHFEEDESASEAIDALNGMLLNGQEIYVGPHLSKKERESKFEEMKANFTNVYIKNINTETTDKEFEELVAKFGKTDSVVLERTPEGENKGFGFVNFVNHEDAVKCVEELNNTEFKGQPLYVNRAQKKYERQQELKKQYEATRMEKMAKYQGINLFIKNLDDSIDDKKLEEEFAPYGTITSAKVMTTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMRFQQASAAAAAAAAAGMPGQFMPPMFYGVMPPRGVPFNGPNPQMANMGAMPKNGMPPHQFRNGPVYGVPPQGGFARNGPAANQFYQQKQRQALGEELYKRIFSRTNDEEAAGKITGMILDLPPQEVVPLLENDELFEQHFKEASAAYESFKQEQQQPQGEEAQQA
What is the function of this protein?
Binds the poly(A) tail of mRNA.  Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.  In the nucleus, involved in both mRNA cleavage and polyadenylation.  Is also required for efficient mRNA export to the cytoplasm.  Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation.  In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein, cytoplasmic and nuclear, PABP, Poly(A)-binding protein, Polyadenylate tail-binding protein.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YBT5_SCHPO
Sequence: MPTELSDITIQSVLPCDYSLFKNNLRVSRLPESRFVFSPKEEINCQSLLQGPELKTALDNLNFIHKQKFEHQFRHGYWKLHPHPHHQHDSIIPASWIHDTPHMKLVFHRLQNLPDGDLLLENDPKNNVGYFISGGIAGIVSRTCTAPLDRLKVMLISDTGSKPSPKYPFATLLHTTKVLWNRNGIRSFFVGNGINVLKVMPESSIKFGTYEAMKRVLGISSSSENHSPLYSYLAGGMAGSVAQMFIYPVDTLKFRIQCSDLSRGQHGKSIILSNAKELYKSVGIRGYYRGVLVGILGMFPYSATDLGTFEGLKRTWIGILASRDNVDPQDVKLPNGLVMAFGALSGSTGATIVFPLNVIRTRLQTQGTSAHPATYDGFIDCFYKTTKNEGFRGLYKGLSPNLLKVAPSVAISYLVYENCKKWLGLE
What are the official names of this protein?
Uncharacterized mitochondrial carrier C12D12.05c.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YCAR_ECO24
Sequence: MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPVLLETEARVLTADESKS
What are the official names of this protein?
UPF0434 protein YcaR.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PKN1_CHLTR
Sequence: MEERAAVEYWGDYKVIAELGHGLWSRDVLAEHRFIKKRYILKILPSELSSSENFMRVFQEVIVQLAAIRHASLVAIENVSREGDRYFVVTEENGGTISLAQYLSGRKLSEEEVVHLIQQLCDALELVHSIGLAHGQIHLHSVHVSFFNGIANIYLPEVGFASLLRERMFSTIMQSGSARESITRIRDLLMFEAPEEQEVFGREADVYSVGVLAYYLLVGSFPWGSFPKPSLCMPDSWYDWDGFILSCLQQQREVRPKCLREALRRKTSGEQLQVTLDSCREPLREMEIEDTPTELGPPSALIREGERLCEVKEEQHAFVLVEAKSIDEVMVTTVDSEEELESSEGYANPLQSLLAREPVVSRYVEVEREEIKPQPLLTEMIFIEGGEFSRGSGDGQRDELPVHNITLPGFFLDIHPVTNEQFVRFLECVGSEQDEHYNELIRLKDSRIQRRSGRLIIEPGYAKHPVVGVTWYGASSYACWIGKRLPSEAEWEVAASGGKLGLRYPTGEEIDKSKANFFSSDTTPVMSYPSSILGLYDMAGNVYEWCQDWYSYDFYESSALEPDAPLGPPQGVYRVLRGGCWKSLKDDLRCAHRHRNNPGAINSTYGFRCAKDVK
What is the function of this protein?
Together with the serine/threonine kinase PknD, may play a role in the specific interactions with host proteins during intracellular growth.  Phosphorylates IncG, an inclusion-membrane protein required for the modification of the nascent chlamydial inclusion.
What are the official names of this protein?
Serine/threonine-protein kinase Pkn1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RL5_LEPBP
Sequence: MVPRLKSKYEKEIRPTLQKSLGFQSVMRVPKLEKIVINVGMGEAHTNPKAMEACLVEIGQITGQRPVKTFAKKSIAGFKVREGMVLGCKVTLRGHHMYEFLDRFINVALPRVRDFRGVNPKGFDGRGNYNLSVREQIIFPEIQFDKINTIYGINITFVTNTEVDKEAFELFQAFGMPYRTAGK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SUCC_SALAI
Sequence: MDLYEYQGRDLFERHGLPVLAGGVATTPEEARAIAERLGGRVVVKAQVKVGGRGKAGGVKLAEGADETVARATDILGMDIKGHTVHKVMITVTADVAEEYYFSYLLDRANRTFLCIASVAGGMDIEQVAAETPEKVVKAPIDANTGVDAAMARQIITRAGFPAEVVDQAVEVAVDLWKAFVAEDATLVEVNPLARTGQGGLLLLDAKVSLDENAAFRHPDHEALVDQAAVDPLEQAAKEKDLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGERHGGVKPANFLDIGGGASAAVMANGLEIVLSDPSVKSVFVNVFGGITACDAVANGIVQALALLEQRGEKVTRPLVVRLDGNNAEAGRAILDGANNPLIQRVDTMDGAAERAAELAAAGV
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PP146_ARATH
Sequence: MLRSITLSPTRRFGFPPRCVSFTTIKELILTEENDGSSLHYAASSPCFLLLSKCTNIDSLRQSHGVLTGNGLMGDISIATKLVSLYGFFGYTKDARLVFDQIPEPDFYLWKVMLRCYCLNKESVEVVKLYDLLMKHGFRYDDIVFSKALKACTELQDLDNGKKIHCQLVKVPSFDNVVLTGLLDMYAKCGEIKSAHKVFNDITLRNVVCWTSMIAGYVKNDLCEEGLVLFNRMRENNVLGNEYTYGTLIMACTKLSALHQGKWFHGCLVKSGIELSSCLVTSLLDMYVKCGDISNARRVFNEHSHVDLVMWTAMIVGYTHNGSVNEALSLFQKMKGVEIKPNCVTIASVLSGCGLIENLELGRSVHGLSIKVGIWDTNVANALVHMYAKCYQNRDAKYVFEMESEKDIVAWNSIISGFSQNGSIHEALFLFHRMNSESVTPNGVTVASLFSACASLGSLAVGSSLHAYSVKLGFLASSSVHVGTALLDFYAKCGDPQSARLIFDTIEEKNTITWSAMIGGYGKQGDTIGSLELFEEMLKKQQKPNESTFTSILSACGHTGMVNEGKKYFSSMYKDYNFTPSTKHYTCMVDMLARAGELEQALDIIEKMPIQPDVRCFGAFLHGCGMHSRFDLGEIVIKKMLDLHPDDASYYVLVSNLYASDGRWNQAKEVRNLMKQRGLSKIAGHSTME
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g03380, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KCNT1_HUMAN
Sequence: MARAKLPRSPSEGKAGPGGAPAGAAAPEEPHGLSPLLPARGGGSVGSDVGQRLPVEDFSLDSSLSQVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDDPALGIGCWGCPKQNYSFNDSSSEINWAPILWVERKMTLWAIQVIVAIISFLETMLLIYLSYKGNIWEQIFRVSFVLEMINTLPFIITIFWPPLRNLFIPVFLNCWLAKHALENMINDFHRAILRTQSAMFNQVLILFCTLLCLVFTGTCGIQHLERAGENLSLLTSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAFHAHKKYGVCLIGLKREDNKSILLNPGPRHILAASDTCFYINITKEENSAFIFKQEEKRKKRAFSGQGLHEGPARLPVHSIIASMGTVAMDLQGTEHRPTQSGGGGGGSKLALPTENGSGSRRPSIAPVLELADSSALLPCDLLSDQSEDEVTPSDDEGLSVVEYVKGYPPNSPYIGSSPTLCHLLPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSITTELTHPSNMRFMQFRAKDSYSLALSKLEKRERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEGDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHVFSTSESQISVNVEDCEDTREVKGPWGSRAGTGGSSQGRHTGGGDPAEHPLLRRKSLQWARRLSRKAPKQAGRAAAAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVANLTASDVMNRVNLGYLQDEMNDHQNTLSYVLINPPPDTRLEPSDIVYLIRSDPLAHVASSSQSRKSSCSHKLSSCNPETRDETQL
What is the function of this protein?
Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits.  Activated by high intracellular sodium or chloride levels.  Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.  May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity).
What are the official names of this protein?
Potassium channel subfamily T member 1, KCa4.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.