PharMolix/UniProtQA huggingface dataset:
Protein: ODO1_STAAR
Sequence: MTNERKEVSEAPVNFGANLGLMLDLYDDFLQDPSSVPEDLQVLFSTIKNDDSIVPALKSTSSQNSDGTIKRVMRLIDNIRQYGHLKADIYPVNPPKRKHVPKLEIEDFDLDQQTLEGISAGIVSDHFADIYDNAYEAILRMEKRYKGPIAFEYTHINNNTERGWLKRRIETPYKVTLNNNEKRALFKQLAYVEGFEKYLHKNFVGAKRFSIEGVDALVPMLQRTITIAAKEGIKNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTDPMKFLPEDGSLQLTAGWTGDVKYHLGGIKTTDSYGTMQRIALANNPSHLEIVAPVVEGRTRAAQDDTQRAGAPTTDHHKAMPIIIHGDAAYPGQGINFETMNLGNLKGYSTGGSLHIITNNRIGFTTEPIDARSTTYSTDVAKGYDVPIFHVNADDVEATIEAIDIAMEFRKEFHKDVVIDLVGYRRFGHNEMDEPSITNPVPYQNIRKHDSVEYVFGKKLVNEGIISEDEMHSFIEQVQKELRQAHDKINKADKMDNPDMEKPAELALPLQADEQSFTFDHLKEINDALLTYPDGFNILKKLNKVLEKRHEPFNKEDGLVDWAQAEQLAFATILQDGTPIRLTGQDSERGTFSHRHAVLHDEQTGETYTPLHHVPDQKATFDIHNSPLSEAAVVGFEYGYNVENKKSFNIWEAQYGDFANMSQMIFDNFLFSSRSKWGERSGLTLFLPHAYEGQGPEHSSARLERFLQLAAENNCTVVNLSSSSNYFHLLRAQAASLDSEQMRPLVVMSPKSLLRNKTVAKPIDEFTSGGFEPILTESYQADKVTKVILATGKMFIDLKEALAKNPDESVLLVAIERLYPFPEEEIEALLAQLPNLEEVSWVQEEPKNQGAWLYVYPYVKVLVADKYDLSYHGRIQRAAPAEGDGEIHKLVQNKIIENALKNN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: ACSA_SHESA
Sequence: MSSQSLYKVSGNIAANALVNNDQYKKMYQESIVNPEGFWREHGKRIDWIKPYTKIKKTTFDDHNLSINWFYDGTLNASANCLDRHLAEHSDRVAIIWEGDNASEQRQITYGELHTQVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSVVFGGFSPDSIASRVIDGKSKVVITADEGMRGGRAIPLKRNIDDALKHPDVTSVEKVIVLKRTGGKVDWVEGRDVWWHSLVETASEHCAIEEMGAEDPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFDYKPGEIYWCTADVGWITGHSYMVYGPLANGATVLIHEGIPNYPSPARLGEMIDRHKVNILYTAPTLIRALMAEGKQHFDKYDGSSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWWQTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGATEGNLVLLDSWPGQMRTVYGDHERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVESALVSHELVAEAAVVGYPHDIKGQGIYAYVTLTRGTEESEELRQELRQWVRKEIGALATPDLIQWATGLPKTRSGKIMRRFLRKIAANEVTNLGDASTLADPAVIETLIETRLNRNE
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RNT_ECO24
Sequence: MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKVVRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPAAEEV
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: MURA1_STAAS
Sequence: MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATKTLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSIHLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAGTLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTANGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDRGYVDLHGKLKQLGADIERIND
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3BHD1_EGGLE
Sequence: MYDDLKGKTVVVTGSSKGLGAAMARRFGAEGMNVVANYRSDEEGARETVRAIEEAGGAAAAVQADVSKNECVDALFDAAMFSFGGVDIWVNNAGIEVASPSDRKSIEEWQRVIDVNLTGVFAGCRRAIDHFLDRKMPGVIINLSSVHEIIPWPHFADYAASKAGVGMLTKTLALEYADRGIRVNAIAPGAMNTPINAEKFADPEARAATERLIPMGYVGAPEDVAAAAAWLASDQASYVTGTTLFVDGGMTLYPGFQFGQG
What is the function of this protein?
Involved in the modification of secondary bile acids into iso-bile acids (3beta-bile acids) via epimerization of the 3-OH group through a 3-oxo-intermediate.  Catalyzes the reduction of 12-alpha-hydroxy-3-oxo-5-beta-cholan-24-oate (3-oxo-DCA) and 3-oxo-5-beta-cholan-24-oate (3-oxo-LCA) to yield isodeoxycholate (isoDCA) and isolithocholate (isoLCA), respectively.  Is also able to catalyze the reduction of 3-dehydrocholate (3-oxo-CA or 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate) and 7-alpha-hydroxy-3-oxo-5-beta-cholan-24-oate (3-oxo-CDCA), into isocholate (isoCA) and isochenodeoxycholate (isoCDCA), respectively.  Prefers NADH to NADPH as cosubstrate.  The conversion of the abundant bile acid deoxycholate (DCA) into isoDCA by the gut bacterium E. lenta favors the growth of the keystone commensal genus Bacteroides, since isoDCA is less cytotoxic than its parent compound, DCA; iso-bile acids have thus a potential role in modulating gut community composition.
What are the official names of this protein?
3beta-hydroxysteroid dehydrogenase 1, 3beta-HSDH 1, 3beta-hydroxycholanate 3-dehydrogenase (NAD(+)) 1, NAD-dependent bile acid 3beta-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PRAP1_HUMAN
Sequence: MRRLLLVTSLVVVLLWEAGAVPAPKVPIKMQVKHWPSEQDPEKAWGARVVEPPEKDDQLVVLFPVQKPKLLTTEEKPRGQGRGPILPGTKAWMETEDTLGHVLSPEPDHDSLYHPPPEEDQGEERPRLWVMPNHQVLLGPEEDQDHIYHPQ
What is the function of this protein?
Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion (By similarity).  Protects the gastrointestinal epithelium from irradiation-induced apoptosis (By similarity).  May play an important role in maintaining normal growth homeostasis in epithelial cells (PubMed:14583459).  Involved in p53/TP53-dependent cell survival after DNA damage (PubMed:23235459).  May down-regulate the expression of MAD1L1 and exert a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas (PubMed:24374861).
What are the official names of this protein?
Proline-rich acidic protein 1, Epididymis tissue protein Li 178, Uterine-specific proline-rich acidic protein.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum.
Protein: ENO_PICTO
Sequence: MNFEIKDTNIRKIFDSRGNFSAEVTVILENASGTASAPAGASTGKTEVIAYPDNNIDNGIDFFYRHVKKALKGFNSINQEGLDRMLHEIDGTDNFSNLGGNIATAISIANAKAVSNALGIPMYRYVGGINYSMPRPIGNVIGGGKHSKNGTTIQEFLVSAQGKTVLDSIYYNILIHRRIGEILSGMFKNQSIGLGDEKAWTCDISDEDAIEIIKNASKDISSEYKIKVLNGVDFAADSFYDGNYYIYKNRKLTRDQQIDYAISISRDHGFYYIEDPLNDQDFDGFSEITSKVGDKSLIVGDDLYTTNPERIKKGIEKRSTNGVLIKVNQIGTLSDTARSVRIATEHGLKTVVSHRSGETTDDFIAHLAVAFGSPLIKTGTIGGERLAKLNELIRIEEELI
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ZDHC5_PONAB
Sequence: MPAESGKRFKPSKYVPVSAAAIFLVGATTLFFAFTCPGLSLYVSPAVPIYNAIMFLFVLANFSMATFMDPGIFPRAEEDEDKEDDFRAPLYKTVEIKGIQVRMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLYVLYHIEELSGVRTADTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTNGCCNNVSRVLCSSPAPRYLGRPKKEKTIVIRPPFLRPEVSDGQITVKIMDNGIQGELRRTKSKGSLEITESQSADAEPPPPPKPDLSRYTGLRTHLGLATNEDSSLLAKDSPPTPTMYKYRPGYSSSSTSAAMPHSSSAKLSRGDSLKEPTSIAESSRHPSYRSEPSLEPESFRSPTFGKSFHFDPLSSGSRSSSLKSAQGTGFELGQLQSIRSEGTTSTSYKSLANQTRNGSLSYDSLLTPSDSPDFESVQAGPEPDPPLGYTSPFLSARLAQQREAERHPRLVPTGPTHREPSPVRYDNLSRHIVASLQEREKLLRQSPPLPGREEEPGLGDSGIQSTPGSGHAPRTSSSSDDSKRSPLGKTPLGRPAVPRFGKPDGLRGRGVGSPEPGPTAPYLGRSMSYSSQKAQPGVSETEEVALQPLLTPKDEVQLKTAYSKSNGQPKSLGSASPGPGQPPLSSPTRGGVKKVSGVGGTTYEISV
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates such as CTNND2, CD36, STAT3 and S1PR1 thus plays a role in various biological processes including cell adhesion, fatty acid uptake, bacterial sensing or cardiac functions.  Plays an important role in the regulation of synapse efficacy by mediating palmitoylation of delta-catenin/CTNND2, thereby increasing synaptic delivery and surface stabilization of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs).  Under basal conditions, remains at the synaptic membrane through FYN-mediated phosphorylation that prevents association with endocytic proteins.  Neuronal activity enhances the internalization and trafficking of DHHC5 from spines to dendritic shafts where it palmitoylates delta-catenin/CTNND2.  Regulates cell adhesion at the plasma membrane by palmitoylating GOLGA7B and DSG2.  Plays a role in innate immune response by mediating the palmitoylation of NOD1 and NOD2 and their proper recruitment to the bacterial entry site and phagosomes.  Participates also in fatty acid uptake by palmitoylating CD36 and thereby targeting it to the plasma membrane.  Upon binding of fatty acids to CD36, gets phosphorylated by LYN leading to inactivation and subsequent CD36 caveolar endocytosis.
What are the official names of this protein?
Palmitoyltransferase ZDHHC5, Zinc finger DHHC domain-containing protein 5, DHHC-5.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YRHF_BACSU
Sequence: MSKKIHEFNDIIRKLRKELFGKGPERIHTVFVENMAVSTLYGNLSASEQFIARTPEGREMVHAARTSLIQDLYSKQTPEGMEELMGAKLVHLFSDIKIEENIAVSVFVFDRKIDEQKEALQS
What are the official names of this protein?
Uncharacterized protein YrhF.
Protein: RSMC_SHEPW
Sequence: MLTNASQVLLRNSDLFKDHSVLVLNYEGDTLPKALLESASSVSALALDFHHHLIMQPYAAKNLQLYFGHQLPTQECFDSVIVYFPKAKALAPYLFNLAGKHLKPQGQLIVVGENKGGIKSLPKQLPDYFDKAFKADNARHCIVFTSELNREAPEIKLQDWYSEYQLQTPQGEITICNMVGVFSEKKLDEGTKLLLENLPKMQGNVLDFGCGAGVIAAALLTAQPKLTLDCVDINAMALTSCDLTMQANGLSANIFASDGMAQTSGHYDGIISNPPFHDGLASTTNIATDFVKAASANLMRGGLFHIVANRHLPYSDCIAENFGEVNVSAENNRYKIYSNIKR
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBIX_ECO8A
Sequence: MMYPIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVRSHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGENEEILSLLNLYHNLLREWSEI
What are the official names of this protein?
PKHD-type hydroxylase YbiX.
Protein: Y913_RHOPA
Sequence: METASKRPKSGAAKKPAAAKARGDGPSYLDGQLLIAMPVMEDERFARSVIYICAHSSEGAMGIIVNRPAGSIDFPELLVQLDIVEKPEQIKLPDHAESMKVLRGGPVETGRGFVLHSSDFFIKDATLPIDDGICLTATVDILKAIAGGTGPKHAILALGYAGWAPGQLENEIQENGWLHCDADADLIFGDDIEEKYDRALHKLGIEPGMLSAEAGHA
What are the official names of this protein?
UPF0301 protein RPA0913.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RR19_CHLRE
Sequence: MSRSLKKGPFVADHLLKKIEKLNAKGKKVVIKTWSRSSMIVPPMIGHTIGVYNGREHIPVFVSDQMVGHRLGEFSPTRTYRGHAKKDKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: QUEA_AGRVS
Sequence: MRVDLFDFDLPDENIALRPANPRDQARFLIVRPDGSLMLEDRRVFELPSFLRAGDALVFNDTKVIPAQLEGVRIREGAERTPVSCTLHMRVAANRWKAFARPGKRIKQGDVIDFDGLSANVAEKGEAGEIDLEFAASGPDLDRAIAGVGHIPLPPYIAAKRPEDSQDRTDYQTIYAREEGAVAAPTAGLHFTPALFEALDKAGIERHFVTLHVGAGTFLPVKADDTDDHKMHQEIGHVSAETAEALNAVKARGGRIVSVGTTSLRLLESAASEDGRLLPWSDATGIFITPGYRFKAVDVLMTNFHLPKSTLFMLVSAFAGLETMRAAYAHAIETGYRFYSYGDSSLLFRKDK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK1_ELAUM
Sequence: METFLFTSESVNEGHPDKLCDQISDAVLDACLAQDPDSKVACETCSKTNMVMVFGEITTKANVDYEKIVRDTCRAIGFVSDDVGLDADNCKVLVNIEQQSPDIAQGVHGHFTKRPEEIGAGDQGHMFGYATDETPEYMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYYNENGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVANGLARRCLVQVSYAIGVPEPLSVFVDSYGTGQIPDKEILNIVKENFDFRPGMITINLDLKRGGNGRFLKTAGYGHFGRDDPDFTWEIVKPLKWEKPQS
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_RUEPO
Sequence: MAMEKTFDAAEAEARITKAWEEAGAFKAGANRSRDESFTIMIPPPNVTGALHVGHAFNNTLQDILTRWHRMRGFDTLWQPGQDHAGIATQMQVEKMLAATQQPSRRELGREEFLKKVWEWKGQYGGTIVEQLKRLGASCDWSRNAFTMAGAAGDPRTGHENSPNFHDAVIKVFVDMYNKGLIYRGKRLVNWDPHFETAISDLEVENIEVAGHMWHFKYPLAGGATYTYVEKDEDGNIVLEEERDYISIATTRPETMLGDGAVAVHPSDERYAPIVGKLCEIPVGPKEHRRQIPIITDEYPDKNFGSGAVKITGAHDFNDYAVAKRGGIPLYRLMDTRGQMRADGAPYAAEAGKAQDYARGRAFTENEIDVINLVPDHLRGLDRFEARAKVVDEITSEGLAVMTVASDPRLGTTALKPGAEGADAIVPLVEAKPIMQPFGDRSKVVIEPMLTDQWFVDAEKVVGPALDAVRDGTVKIIPESGEKTYYHWLENIEPWCISRQLWWGHQIPVWYGPNRDDLGASYKAFCAASEQDALLLAQNYYGANVEVDFDSGPEELSGGIAFGTIEGPGGQKTLQSVSLTRDPDVLDTWFSSGLWPIGTLGWPEDTDEMRRYFPTSVLITGFDILFFWVARMMMMQLAVVDQVPFHTVYLHQLVRDEKGKKMSKTTGNVIDPLEIVDEFGADALRFTNASMAAIGGVLKLSKERITGYRNFTTKLWNAIRFAEMNEVFTDAVPQLSAAELAPKAAVNRWIIGETARVREEVDAALDSYRFNDAANALYAFVWGKVCDWYVELSKPLLQGEDTEAQAETRATMRWVMDQCLVLLHPIMPFITEELWGLTAERAKMLVHADWPTYKAADLVDDAADREMNWVISVIENTRSARAQMRVPAGLYVPMIVTEIDDHGQAAWDRNEALIKRLARIDSLTKADAMPKGCISIAAPGAAFGLPLAEIIDIGAEKDRLEKAKGKLAKELGGLRGRLNNPKFVESAPDEVVEEARENLAAREEEEARLNEALARLAELG
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSE1_HUMAN
Sequence: MQGSTRRMGVMTDVHRRFLQLLMTHGVLEEWDVKRLQTHCYKVHDRNATVDKLEDFINNINSVLESLYIEIKRGVTEDDGRPIYALVNLATTSISKMATDFAENELDLFRKALELIIDSETGFASSTNILNLVDQLKGKKMRKKEAEQVLQKFVQNKWLIEKEGEFTLHGRAILEMEQYIRETYPDAVKICNICHSLLIQGQSCETCGIRMHLPCVAKYFQSNAEPRCPHCNDYWPHEIPKVFDPEKERESGVLKSNKKSLRSRQH
What is the function of this protein?
RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate.  Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex.  Involved in maintenance of genome integrity, DNA damage response and DNA repair (PubMed:29225034, PubMed:20864041).  NSMCE3/MAGEG1 and NSMCE1 ubiquitin ligase are components of SMC5-SMC6 complex and may positively regulate homologous recombination-mediated DNA repair (PubMed:18086888).  MAGEF1-NSMCE1 ubiquitin ligase promotes proteasomal degradation of MMS19, a key component of the cytosolic iron-sulfur protein assembly (CIA) machinery.  Down-regulation of MMS19 impairs the activity of several DNA repair and metabolism enzymes such as ERCC2/XPD, FANCJ, RTEL1 and POLD1 that require iron-sulfur clusters as cofactors (PubMed:29225034).
What are the official names of this protein?
Non-structural maintenance of chromosomes element 1 homolog, Non-SMC element 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the NSE1 family.
Protein: RPOB1_TETOB
Sequence: MYNSNSYIPDLVEIQRQGFFYLLEKGIIEEISKRNPITCFEKQIEIFFYPQYYRLTKPFYSIQQAIFYKKSYVSKFYIPVQLTDRKTKRIFLKWILLAHFPLMTNRGHFLLNGSARVIINQLVRSPGIYFRENMHEIFSNKWSEKPSTTFRRFYADIICLKGTWLRIECDKDFSMWAKMKKGPKIPLLWFLLGMGLSEKYILNSVYKPMNLLQSFTKEMEKMQKSKSSKELKYPYISSTKQAWEQIQKLFKLKKTLRKFSFLKKNEEKPKTFIFGQSSTKIEAKVVFSDFAAFNNSVKRENTVFASNDDTFLVQTSFETKKKKNTRKKENFQKNKTQKTTKLSLQNKEKRVASKLEAYELGRKWFANKFMNPRTYDLGKQGRWLINKKLGLTIPLEQTTLTALDVLTATDSLMKIEDGFFEIDDIDHLKNKRVRTAGEALQEIFSIGLIRLEKSIRLKLNGNGQQSFFQKTSFFNFDSLMSTRPINGAFREFFGTHPLSQFMDQINPLAEITHKRRLSSLGPGGVSRDTATLAIRGIHPSHYGRICPIETPEGKNTGLVNSITTYSKISFHGYLESPFYKVYKGQVQRNLGVFYLSPDKDDHFQTATPDLNLTPLGFLPKKPIPVRIGKRFVRMKTHKLALMGVSPLQMISVATSFIPFLEHDDANRALMGSNMQRQAVPLIRPERPLIGTGLEARVVSDSGHAILAKTSGYIVYSSGSKIYLYTI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta N-terminal section, PEP, Plastid-encoded RNA polymerase subunit beta N-terminal section, RNA polymerase subunit beta N-terminal section.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GCST_BURM9
Sequence: MTVLKTTPLHAAHRALNARMVDFGGWDMPVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHAIANNVAKLQTPGKALYSCLLNPQGGVIDDLIVYYFTEEFFRVVVNAGTAEKDIAWFNQLNEQGGFGLTIAPRRDFAIVAAQGPNARAKVWDTVPCARAATSELKPFNAAQVAGTPFGDLTVARTGYTGEDGFEIIVPATHVEALWNALAERGVRPCGLGARDTLRLEAGMNLYGQDMDESVSPLDAGLAWTVDLSAPRAFVGRDALEAHGSRAAFVGLILQKENGRAGGVLRAHQKVATPHGEGEITSGTFSPSMQESIAFARVPKDVAIGDTVHVQIRDKQLPARVVKLPFVRNGKVLAA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RS15_RHIL3
Sequence: MSITAERKSALIKEYATVEGDTGSPEVQVAILTERINNLTEHFKDHKKDNHSRRGLLTMVSSRRSLLDYLKKKDEGRYSKLITSLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: UBID_PHOPR
Sequence: MKFKDLRDFIDYLEQEGQLKRIKQPIDPNQEITEICDRTLRAGGPALLFENPIGYDIPILANLFGTPERVAMGMGRQDVKELREVGKLLAYLKEPEPPRGFRDAMDKLPVFKQVFNMPTKRLRKAPCQQVIWQGDDVDLDKIPVMSCWPDDVAPLLTWGLTITKGPNKPRQNLGIYRQQKIAKNKVIMRWLAHRGGALDLRDWMDTHPGEPFPISVAFGADPATILGAVTPVPDTLSEYAFAGLLRGSKTEVVKSLSNDLDIPASAEIVLEGYIDPNEFADEGPYGDHTGYYNEVERHHVFTITHVTMREDPIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRMAVVTMKKQYPGHAKRVMMGVWSFLRQFMYTKFVIVLDDDVNARDWNSVIQAMTTRMDPVRDTLLIESTPIDSLDFASPVVGLGSKMGLDATVKWEAETASTPSGTSQAAPDFDIETGTRNLLMQFPEIVDFYLPQEADKNSMAIVSIKKDAAGHATRVMDGVWSFLSQFTDAKFVIVCDDDVNVRDWNDVIWAITTRMDPSRDTLLIANAPIDSLDLTSPVVGLGSKMGLDATNKWQGETAREWGRPITKDPEIVAKVDAIWNELGILD
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: COTB4_STRMJ
Sequence: MKDFFRMRTAQQPATRHWRHTVAPGGLPLAGHALLMARKPLQFLASLPAHGDLVELRLGPRPVYLPCHPELVQQVLVNARVYDTGGPVKEKAKPILGNGLITSDWADHRRQRRLVQPAFHTARIAKYAEVMERECEAESTAWTARRPIDVSHEMLALTARVTARALFSTDMAPHAVAEIQHCLPIVVEGAYRQAIDPTGLLAKLPLAANRRFDDALARLNQLIDRMIDDYKASDDGDRGDVLSALFAAQDDETGGTMSDQEIHDQVMTLLLAGIETTASALTWAWFLLGRNPGAEAALHAEVDEVLGGRAPRYADVPRLAYTQRVFSEALRLFPPAWLFTRTTTETTELGGRRLPPASDVLISPYVLHRDPALFPRPDSFDPDRWLPERAKEVTRGSYLPFGGGSRKCIGDVFGMTEATLALAAIAGRWRMRPIPGTKIRPRPQMSLTAGPLRMIPEPR
What is the function of this protein?
Involved in the biosynthesis of cyclooctatin, a potent inhibitor of lysophospholipase.  Catalyzes the hydroxylation of cyclooctat-9-ene-5,7-diol at C-18 to yield the final product, cyclooctatin.
What are the official names of this protein?
Cyclooctatin synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RS3_PSE14
Sequence: MGQKVHPIGIRLGIVKEHTSVWYADGRTYADYLFADLKVREYLQDKLKSASVSRIDIHRPAQTARITIHTARPGIVIGKKGEDVEKLRQDLTKQMGVPVHINIEEIRKPELDGMLVAQSVAQQLERRVMFRRAMKRAVQNAMRIGAKGIKIQVSGRLGGAEIARTEWYREGRVPLHTLRADIDYANYEAHTTYGVIGVKVWIFKGEVIGGRQEELKPQAPAPRKKAAK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ISPD_TRIV2
Sequence: MYLLIPAAGVGKRMGCDRNKLLLEVRSQPIIAWTLLAAQAASEISWIGIISQPTDWPDFKSILANLQLTKPVEFILGGSTRQESVYNGLQALPKAAEQVLIHDGARCLATPNLLNSCAQAIRHCSGLIAAVPVKDTIKVADEDGIIQSTPDRRNLWAAQTPQGFNVELLKQCHAEGVRQGWEVTDDAALFEKCGIEVQIVEGEETNLKVTTPQDLAIAEFILNSRDNS
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.