PharMolix/UniProtQA huggingface dataset:
Protein: BLT1_ECOLX
Sequence: MMTQSIRRSMLTVMATLPLLFSSATLHAQANSVQQQLEALEKSSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKQSESDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGPDKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRAQLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQPEQKAERRRDILAAAAKIVTHGF
What is the function of this protein?
Has strong cefotaxime-hydrolyzing activity.
What are the official names of this protein?
Beta-lactamase Toho-1.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: LUXS_CAMC5
Sequence: MPLLDSFCVDHTIMNAPGVRLAKTMDTPKGDKICVFDLRFCKPNETMMPERGTHTLEHLFAGFMRDHLNREGVEIIDISPMGCRTGFYMSVIGEPSSQEVANAWEASMKDIINVLSQSDIPELNEYQCGSYKMHSLKEAHEIANNVLKAGIGIIDNESIKLDLHAKGLKKH
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: MANBA_CAEEL
Sequence: MRTSLVVCLFWLLFQLHTTHGYNTLVNLAGNWEFSSSNKTVNGTGTVPGDIYSDLYASGIIDNPLFGENHLNLKWIAEDDWTYSRKFRLIDLDDTVGAFLEIESVDTIATVYVNGQKVLHSRNQFLPYHVNVTDIIALGENDITIKFKSSVKYAEKRADEYKKIFGHSLPPDCNPDIYHGECHQNFIRKAQYSFAWDWGPSFPTVGIPSTITINIYRGQYFHDFNWKTRFAHGKWKVAFEFDTFHYGARTIEYSVQIPELGIKESDYYRLSATKSLQTRSKNIMSLSIPMEHEPERWWPNGMGEQKLYDVVVSMGGQVKEKKIGFKTVELVQDLIDPKKPEKGRNFYFKINDEPVFLKGTNWIPVSMFRSDRENIAKTEFLLDSVAEVGMNAIRVWGGGFYESNHFYYYASKKGILVWQDLMFACALYPTTEEFIQNAEEEVSYNVDRISQHTSVIVFSGNNENEAAIRGHWWKASNYTESQQVKDYVLLYQRLAKIAKKVAPTIPFIMSSPSNGVETEEEGGVSKNPYDVRYGDIHYYNEFVNLWRDDTYLTPRCASEYGVQSYPMKETMLNWINESDWEYTSKAMFHRQHHPGGIATNLLMIFQHLPIPAECGSKSVSDVPSCKYISSASYMSRLAYFSQVHQSIALKTQTLHYRRFRNTTTNEGLGNTMCAMYWQLNDVWAAPTWSTIDFEQNWKMAHYEARRFFSNVAVYSFADETDFNLKVFLLNDNPYLLHNITVNVQMLSWGNGLDPILTNEFHIDSVPAGSSEVLKTGITFSKITELSEYLYVSTLYDSSGVKIHEDVLVPDFLFEVDFNTFGDVQISDVQRIDEKTYDLTITTDRVSPFTWITCKKPFTGWFSDNGFHMIQRLRKIRLIAKFEVDLEKSDFTVCNLKNCYV
What are the official names of this protein?
Probable beta-mannosidase, Mannanase, Mannase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: YAM3_SCHPO
Sequence: MSNSRNIVIVGGGITGVSCLYFLAHHPSFNRDRDTITLFESAGIASAASGKASGFLSLEWHGPSTSSLAALSYNLHKELSDQYDGVNKWGYRALDTWSIKADENCQQPDKLPEGIEWIAPSIVENVTRLGNKKNSGQVHPYKFCHAIYEEASKVANVTLVKGHVLSVDENEVEYRLIGDDYAPDEEEEITSAEELHTIHSMEATHIIVAAGPWTPQLIPNLRISGARIHSITIDLPIKLNGNAVFSEITYKDGTIAAPEFYAREDELYVCGEFDDEPLPELSSDTKVDQDKCALIKQCANHFHQIIRDSPVKVRQACYLPISNATGAPVIGKIGSSIYVAAAHGCWGITLGPGTGKVLSELILDGAVTSANIDLLDPEGSLE
What is the function of this protein?
Putative oxidoreductase that negatively regulates the retrieval of cargo from late endosomes to the Golgi.
What are the official names of this protein?
Putative oxidoreductase C1F5.03c.
What is the protein family that this protein belongs to?
Belongs to the TDA3 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Single-pass membrane protein.
Protein: SUCC_CAMC5
Sequence: MNIHEFQAKEILKRYGVNVAKGAVAENLEQASEILNDLEGEIFALKAQIHAGGRGLAGGVKIASSREQAIQFASKLLGMTLITPQTPKNGILVRKIYIEEGLNFKQEIYLSLAFDRNSEKISLIVSKDGGVSIEETAKQNPHLIKTISIDPQIGLCGFHTKELINFLQIDKILWSKLDTLLQNLYKIYIFKDANLIEINPLVLTQDDEFYALDAKMSFDDSALFRHEDIRALNDETQTDTSENEAKAQRLNYIKLEGSVGCVVNGAGLAMATMDIIKELGGEAANFLDVGGAATGEGVAKAFRLILNDRRVKVIFVNIFGGIVRCDRIAAGIIEACQSTPLGVPVVVRLDGTNAKEALDMLKNSALKGLHTSDDLFEGARLAVMLAKGEK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PMPA_CHLTR
Sequence: MNRVIEIHAHYDQRQLSQSPNTNFLVHHPYLTLIPKFLLGALIVYAPYSFAEMELAISGHKQGKDRDTFTMISSCPEGTNYIINRKLILSDFSLLNKVSSGGAFRNLAGKISFLGKNSSASIHFKHININGFGAGVFSESSIEFTDLRKLVAFGSESTGGIFTAKEDISFKNNHHIAFRNNITKGNGGVIQLQGDMKGSVSFVDQRGAIIFTNNQAVTSSSMKHSGRGGAISGDFAGSRILFLNNQQITFEGNSAVHGGAIYNKNGLVEFLGNAGPLAFKENTTIANGGAIYTSNFKANQQTSPILFSQNHANKKGGAIYAQYVNLEQNQDTIRFEKNTAKEGGGAITSSQCSITAHNTIIFSDNAAGDLGGGAILLEGKKPSLTLIAHSGNIAFSGNTMLHITKKASLDRHNSILIKEAPYKIQLAANKNHSIHFFDPVMALSASSSPIQINAPEYETPFFSPKGMIVFSGANLLDDAREDVANRTSIFNQPVHLYNGTLSIENGAHLIVQSFKQTGGRISLSPGSSLALYTMNSFFHGNISSKEPLEINGLSFGVDISPSNLQAEIRAGNAPLRLSGSPSIHDPEGLFYENRDTAASPYQMEILLTSDKIVDISKFTTDSLVTNKQSGFQGAWHFSWQPNTINNTKQKILRASWLPTGEYVLESNRVGRAVPNSLWSTFLLLQTASHNLGDHLCNNRSLIPTSYFGVLIGGTGAEMSTHSSEEESFISRLGATGTSIIRLTPSLTLSGGGSHMFGDSFVADLPEHITSEGIVQNVGLTHVWGPLTVNSTLCAALDHNAMVRICSKKDHTYGKWDTFGMRGTLGASYTFLEYDQTMRVFSFANIEATNILQRAFTETGYNPRSFSKTKLLNIAIPIGIGYEFCLGNSSFALLGKGSIGYSRDIKRENPSTLAHLAMNDFAWTTNGCSVPTSAHTLANQLILRYKACSLYITAYTINREGKNLSNSLSCGGYVGF
What are the official names of this protein?
Probable outer membrane protein PmpA, Polymorphic membrane protein A.
What is the protein family that this protein belongs to?
Belongs to the PMP outer membrane protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell outer membrane; Peripheral membrane protein; Extracellular side.
Protein: KTHY_XANCP
Sequence: MTIELTPGGLLIAIEGIDGAGKTTLARSLATLLEQAGARVVLSKEPTNGPWGTQLRQSAATGRLSAQDEVDLLLRDRREHVEALIAPALARGEIVILDRYFPSMVAYQGAAGLPLDALLAANDFAPRPDLLLLLDLPPPTGLARIRARGDAPNHFETQDNLERCRAIFAALQLPGKHVIDASADADSVLRQAHAVVVAALADRLRVGATHTDAEKAALELLSAGRPA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NUOI_EHRCR
Sequence: MIYKKNFSKLSPITNLIRSALLNCRGMYITLRYMFKPKVTLNYPLEKGPLSTRFRGEHALRKYKNGEERCIACKLCEAICPAQAITIEAQERDDGSRRTVRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEYATETREELMYNKSKLLHNGQIWEEAIDLRIKKNSQFY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: APT_SALDC
Sequence: MTATAQQLEFLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIELLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPRKLPRETIAETYELEYGTDQLEIHVDAIKPGDNVLVVDDLLATGGTIEATVKLIRRLGGKVTDAAFIINLFDLGGEQRLEKQGITCYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMEL_TACAC
Sequence: LHHQIIPVLSQHQTPTHALQSHHHIPVMATQQPTQPPQPMMPMPGQHSVTPTQHHQSNLPQPGQQPFQPQFPQKPTHRPIQPQAPVHPMPPMPQPQLPPMFPLQPLPPLLPDLPLEPWPAS
What is the function of this protein?
Plays a role in the biomineralization of teeth.  Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development.  Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity).
What are the official names of this protein?
Amelogenin.
What is the protein family that this protein belongs to?
Belongs to the amelogenin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: EFP_STRPZ
Sequence: MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQELLYILENSNVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVVNVPDFIEAGQKLIINTAEGTYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H962L_ASFM2
Sequence: MGKPTLLEPGHLYNVPAEHKNDIPIHYIITWIKQRLPEFGGAIPTSLADRVLIIKSRTGSGKSTALPVHVFRILRNENTHSFQKYLGRSVICTQPRVLTAVTLAKDIGASTHYPDMILGQTVGYQTKPLTEKPNRGLIYATAGVLLAQLHTMTDDEIASRYAFMIIDEAHERALGIDLMLMYIKSMLERMLQRGSIGALRIPFVILTSATIDTHKYSTYFGIGKENIILVEGRQFGVETHWPLYNTNNYIKTACETALTIHKENIHDRPTEADILIFMPGMGEIRFLSTLLNNANMDLAKEKLPLMLILPIDSEAIAQENEAYLGLKAEIKNLWVKNPLTAKVEKPLRRVIVSTVVAETGLTIETLKYVIDPGWNRSVETYYPEWAGGLITRPAAQSRIEQRKGRVGRVFPGHFYPLYTKHVFEQIPAQQYPEIITEGPGAIFLNIVVETIKKNKEGVFKAEEIDMLDPPPTDALASAIERAIVGGLLTRGEKGLQLTQLGDIASRFSFLSIEEARMCFSGYFWQAAISDIAIILAVVSVVDKKLTNLLDSKQRNGAMLAEAVLAGIPPFLQHIDNAYTNIHLLLADDLLEGLFIFEGFQHAIVYFINNKVNNLAKHLREWCEKKMLKYSSMVQILARREDILNELAIVGLNPFHQWQNRLASANAETFLKRVCTLKQCIYEAYRLNCFCYDEHRLLYTGRNGIHFSYHDTVIKNPSCIVTPRIMLAPVSKQYMEWRLEPSFVSVLDGFVNMDINFLLPRQEIPNILGGVEDEEEEEPPLPIQVFLHNYVKTHFHFSGKSFKELKMKPSQMIKFPETTLINMIPDIPKNVVQTYLEINVCHQYSFKRLIYCETFYTNMDDVQHENAVELIGLPMAAHHLTINDFNKLYRVLKPDGFLIVYDLHNSQEAYWLHSLQDALGHHTIRRDMDFHTITEWETIFKECGFSPIFSKQPSEHELFIVFKK
What are the official names of this protein?
Putative RNA Helicase B962L.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: THIE_GEOTN
Sequence: MARITSEEMKERLAVYFIMGSQNSERPAEDVLKEALDGGVTLFQFREKGSAALEGEEKEALARQLQRLCRTYGVPFIVNDDVELAIAIDADGVHVGQDDEDARRVREKIGDKILGVSAHNVEEARAAIEAGADYIGVGPIYPTRSKDDANEAQGPGILRHLREQGITIPIVAIGGITADNTRAVIEAGADGVSVISAIASAPEPKAAAAALATAVREANLR
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RL5_BURM9
Sequence: MARFQEFYKEKVVPGLIEKFGYKSVMEVPRITKITLNMGLGEAVADKKIIENAVGDLTKIAGQKPVVTKARKAIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSGRAFDGRGNYNIGVKEQIIFPEIDYDKIDALRGLNISITTTAKTDDEAKALLASFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: KDSA_RALSO
Sequence: MKLCDFEIGLDRPFFLIAGTCVIESEQMAIDTAGTLKEITGALGIPFIYKSSFDKANRSSDASFRGLGMEEGLRILAEVRRQVGVPVLTDIHEIDEIKPVASVVDVLQTPAFLCRQTDFIRACAQSGKPVNIKKGQFLAPHDMKNVIDKARHAARDAGLPEDSFMACERGASFGYNNLVSDMRSLAIMRETGAPVVFDATHSVQLPGGQGTSSGGQREFVPVLARAAVATGVAGVFMETHPDPACAKSDGPNAVPLRRMKDLLSVLKELDTLTKRNGFLENQFD
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A09_CYRHA
Sequence: MKVTLIAILTCAAVLVLRTTAAEELEAESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Neurotoxin active on both insects and mammals.
What are the official names of this protein?
U4-theraphotoxin-Hhn1a, U4-TRTX-Hhn1a, Hainantoxin-II.9, HNTX-II.9, Peptide F8-20.15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BLAR_STAAU
Sequence: MAKLLIMSIVSFCFIFLLLLFFRYILKRYFNYMLNYKVWYLTLLAGLIPFIPIKFSLFKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFATDIHKFNWDSIDNISTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRKAETIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFNIFSIIMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLNVPFFNKNILSHSFNGKKSLLKRRLINIKEANLKKQSKLILIFICIFTFLLMVIQSQFLMGQSITDYNYKKPLHNDYQILDKSKIFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPNSTYKIYLAMFGLDRHIINDENSRMSWNHKHYPFDAWNKEQDLNTAMQNSVNWYFERISDQIPKNYTATQLKQLNYGNKNLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKKNEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGKPSGKNAELISEKILKEMGVLNGQ
What is the function of this protein?
Integral membrane protein involved in sensing of the presence of beta-lactam antibiotics and transduction of the information to the cytoplasm.  Mechanistically, activation of the signal transducer involves acylation of a serine in the C-terminal sensor domain upon binding of the beta-lactam antibiotic (PubMed:12591921, PubMed:15506754).  In turn, a conformational change occurs and the signal is transmitted from the cell surface to the cytoplasm.  There, the zinc protease domain is activated and initiates autoproteolysis as well as cleavage of the transcriptional repressor BlaI leading to derepression of antibiotic resistance genes (PubMed:11239156).
What are the official names of this protein?
Regulatory protein BlaR1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M56 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AN13C_DANRE
Sequence: MTGEKIRSVRKERKSGLDLLEPDEEPAATGPAKHRGSKIFSGGNHRISRSSSSPGDPDGAYPVHECVFRGDVRRLSSLIRTQNIAQKDVHGNTPLHLAVMMGHKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVEDKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFCGDAPPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDVYSATLSTKSITFSRAQTGWLFREDKTERVGNFLADFYMVNGLVLESRKRREHLSEEDILRNKAIMESFSKGGSLIEQNFEPMRRQSLTPPSPNTISWEEYITAETGKAPHLGRELVCKESKKNFKATVAMSPDFPLGIESLLNVLEVIAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRYDEFDESIFTIPSDYKGDPSRFPDL
What is the function of this protein?
Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 13C.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Note=Associated with the cytosolic side.
Protein: LNT_RICTY
Sequence: MYKTKIICFLLGILSGLVFAPTFFIPALFTFSYLCYIVQKSQNWQAAAKFGYLFGFGHFLSGMYWISIGVSVYIADFWWAIPFALFGLPIILAFFISTNCTLSFFAKNNKYYQLIFCLLWVLFEWIRSWICTGLPWNLIGYAFSFSEILIQPLSITGIYGLSFIVIYIATSAYPVFSKNFTKLKILLASSMLILTVMVIYGAMRVSTNPTHFTDIKVRLVQPSIPQTAKWDEEEFWHNLMLHINLSEKLEPTDLIIWSEAALVVPDDIPQVKLELLNMLNSTNAILITGGISDNKKHGDKFELYSAMYALDKNNHKLFEYHKSHLVPFGEYMPLKKILPFKKLTHGLIDYKEGNGGLVYIKKYHLKIKPLICYESIFPNFVQTNNEIADVIINITNDSWYGKSSGPYQHFHISRSRAVENGLPMIRVANNGISAIVDPVGRIVKKLNLNEINYIQGLIPQKLTTPTIFSQFGNFAMLLPIVFILLIHYLLSLIFDD
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FIBB_ODOHE
Sequence: QHLADYDEVDDDRAKLHLDAR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: PSS_RHILP
Sequence: MDLVLKRAFDIFSSLSALLVLAPFLLFVALLIKLDSPGPVLFKQTRWGKNCKAIKVYKFRSMRTDLCDVSGVAQTVKNDPRITRIGAILRRTNVDELPQLLNVLLGHMSVVGPRCHAIGMRAGGMLYEELVPEYHQRHAMRPGMTGLAQMRGLRGPTDRPAKARARIASDLYYVGNFSIVMDMRIIFGTVVSELTRGKGF
What are the official names of this protein?
Exopolysaccharide production protein PSS.
What is the protein family that this protein belongs to?
Belongs to the bacterial sugar transferase family.
Protein: PANC_KORVE
Sequence: MRVVRTIAEMQAICRTLHREGKSIGLVPTMGALHAGHISLVRTARTQNDSVVVSIFVNPIQFGPNEDLAKYPRTFEQDCAQLDHEGVDFVFSPGVEEMYPEGTATFVHVDGLSEKLDGRSRPGHFKGVTTVVSKLFHIIPADHAYFGQKDAAQVAVIRKMVRDQNFDIDLMICPIVREKDGLALSSRNAYLDPTQRQQALVLHRALMRVQMLADTGHTDAYYLAEAGRAVIAEEPGAKLDYLEIVDPNTLEPITEIGKGALVAVAAQIGNTRLIDNLVLQAAGNARGPRTS
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED7_DROME
Sequence: MSNQETQVSSLPMPPERYIANYTDENIRRNRAPRPPPPPAQHEVYSMFGIQYNNDEMIRSLESQNIKRLIPIHFDRRKELKKLNHSLLVNFLDLIDFLILNPDSPRRTEKIDDISLLFVNMHHLLNEFRPHQARETLRVMMEMQKRQRVETAARFQKHLERVREIVNTAFSALPVLDDDDDSGGAKIKTEVDPLEANAAAKNDPSYQHDRMLCKLVDAIE
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).  Required for activated transcription of the MtnA, MtnB and MtnD genes.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, Mediator complex subunit 7, dMED7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HPR2_ARATH
Sequence: MESIGVLMMCPMSSYLENELEKRFNLLRFWTSPEKSVLLETHRNSIRAVVGNASAGADAQLISDLPNLEIVSSFSVGLDKIDLGKCKEKGIRVTNTPDVLTEDVADLAIGLILALLRRLCECDRYVRSGKWKQGEFQLTTKFSGKSVGIIGLGRIGTAIAKRAEAFSCPINYYSRTIKPDVAYKYYPTVVDLAQNSDILVVACPLTEQTRHIVDRQVMDALGAKGVLINIGRGPHVDEQELIKALTEGRLGGAALDVFEQEPHVPEELFGLENVVLLPHVGSGTVETRNAMADLVVGNLEAHFSGKSLLTPVV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate (HP) into glycolate and glycerate in the cytoplasm, thus providing a cytosolic bypass to the photorespiratory core cycle.  Mostly active in the presence of NADPH and hydroxypyruvate.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A HPR2, NAD(P)H-dependent hydroxypyruvate reductase 2, AtHPR2, HPR 2.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCO22_RICTY
Sequence: MQSNIMKIIIIVSLLIVVGTLYVLLSLSTPKKPLAGQVNIYKDNIKIGEAFELIDQNGEIFNSNKLRGHLSLIYFGFTSCPDICPTFLNKMTNIVEILHQNQIDIIPIFITIDPKRDTPEVLKEYIKNFHPKFICLTGNEHQIKDVTDKFKILYARVNGYDDDQNYMIDHSSFTYLIDKNGKYIKHFYLDISAKEIMEFLRNE
What are the official names of this protein?
SCO2-like protein RT0576.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
Protein: GRF5_ARATH
Sequence: MMSLSGSSGRTIGRPPFTPTQWEELEHQALIYKYMVSGVPVPPELIFSIRRSLDTSLVSRLLPHQSLGWGCYQMGFGRKPDPEPGRCRRTDGKKWRCSREAYPDSKYCEKHMHRGRNRARKSLDQNQTTTTPLTSPSLSFTNNNNPSPTLSSSSSSNSSSTTYSASSSSMDAYSNSNRFGLGGSSSNTRGYFNSHSLDYPYPSTSPKQQQQTLHHASALSLHQNTNSTSQFNVLASATDHKDFRYFQGIGERVGGVGERTFFPEASRSFQDSPYHHHQQPLATVMNDPYHHCSTDHNKIDHHHTYSSSSSSQHLHHDHDHRQQQCFVLGADMFNKPTRSVLANSSRQDQNQEEDEKDSSESSKKSLHHFFGEDWAQNKNSSDSWLDLSSHSRLDTGS
What is the function of this protein?
Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues.  Acts together with GIF1 for the development of appropriate leaf size and shape through the promotion and/or maintenance of cell proliferation activity in leaf primordia.
What are the official names of this protein?
Growth-regulating factor 5, AtGRF5, Transcription activator GRF5.
What is the protein family that this protein belongs to?
Belongs to the GRF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAA_SHESM
Sequence: MTSKNPIQKALYLAFERAQWSVLRDAVPMTLSEQDLENLRGINEKVSLTEVTDIYLPLSRLLNLIVKAKQQRGLVLDEFLGQKPSSSPYIISIAGSVAVGKSTTARILQALLRHWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFIAAVKSGQAHVNAPIYSHVTYDRIRGQHQTVSQPDILILEGLNVLQTGLDSPVDIRRPFVSDFVDFSIYVDAEEHLLKQWYQERFLQFRKGAFSDEKSYFHHYASLTDDEANVIAAKIWDTINGPNLQLNIQPTRERAHLILQKGQDHLMSHVLLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.