PharMolix/UniProtQA huggingface dataset:
Protein: CNGC9_ARATH
Sequence: MLDCGKKAVKSQVISGRLEKFVRLDSMDSRYSQTSDTGLNRCTLNLQGPTRGGGAQGNNVSSGSFKKGFRKGSKGLWSIGRSIGLGVSRAVFPEDLKVSEKKIFDPQDKFLLLCNKLFVTSCILAVSVDPLFLYLPFVKDNEKCIGIDRKLAIIATTLRTVIDAFYLFHMALRFRTAFVAPSSRVFGRGELVIDPAQIAKRYLQQYFIIDFLSVLPLPQIVVWRFLYISKGASVLATKRALRSIILVQYIPRFIRLYPLSSELKRTAGVFAETAWAGAAYYLLLYMLASHIVGAIWYLLALERYNGCWTKVCSNSSLDCHRNFLFCGNEKMDGYAAWTTIKDSVLQLNCPVNTTDNPPFDFGIYLRALSSGIVSSKSFVSKYFFCLWWGLQNLSTLGQGLETSTYPGEVIFSIALAIAGLLLFALLIGNMQTYLQSLTIRLEEMRVKRRDSEQWMHHRMLPPELRERVRRYDQYKWLETRGVDEENLVQNLPKDLRRDIKRHLCLALVRRVPLFENMDERLLDAICERLKPCLYTESSYLVREGDPVNEMLFIIRGRLESVTTDGGRSGFFNRSLLKEGDFCGEELLTWALDPKSGSNLPSSTRTAKALTEVEAFALIADELKFVASQFRRLHSRQVQHTFRFYSQQWRTWAAIFIQAAWRRYVKKKKLEQLRKEEEEGEGSVTSIRATFLASKFAANALRKVHKNRIEAKSTIELVKYQKPSEPDFSADDTS
What is the function of this protein?
Putative cyclic nucleotide-gated ion channel.
What are the official names of this protein?
Putative cyclic nucleotide-gated ion channel 9, Cyclic nucleotide- and calmodulin-regulated ion channel 9.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLND_ALIFM
Sequence: MKYLSPLSLSDTQLNITELKQQLTLFSQYQINAFHQHKAVSDLVFERSHYFDQLLSRLWQFFKFDDIANTSLIAVGGYGRSELHPLSDIDILILTENNTNDTFCQKVGELVTLLWDLKLEIGHSVRSIAECIEIGQNDLTVATNLQEARYICGNKELSHQLKLKIHSDSFWPSESFYQAKIDEQKKRHSRYHDTTYNLEPDIKSSPGGLRDIHTLSWIARRHFGATSLLEMSQAGFLTDAEYRELLECQEFLWRVRFALHIELKRYDNRLTFGHQASVAEHLGFIGEGNRGVERMMKEFYRTLRRVAELNSMLLKIFDQAILHQGEQDDAIIIDDDFQRRGRLIEARKPALFQARPDTILDMFLLMANDSTIDGVAPPTMRQLRTARRRLNRFLCEIPEAKEKFLQLTQHPNALNNAFSSMHKLGVLSAYLPQWSHIVGQMQFDLFHAYTVDEHSIRLLKHINKFSDTTNRDKHPICCEIFPKIMKKELLIIAAIFHDIAKGRGGDHSELGAVDAYDFCISHGLSKPEANLVSWLVKSHLLMSVTAQRRDIYDPDVITEFAKQVRDEERLDYLVCLTVADICATNPDLWNSWKRSLIADLYNATQRALRRGLENPPDLRDRIRHNQQMASAQLRSEGFTQWEVDALWRRFKADYFLRHTHKQIAWHASHLLRHQDKEKSLILISKNASRGGTEIFVYSKDQPHLFATVAAELDRRSITIYDAQVMSSKDGYALDTFMVLDQNDDPIDEERQQRLIDQLYDVKLNDQATHIKTRRPPRQLQHFNVKTRMEFLPTKTGKRTLMEFVALDTPGLLATVGATFAQLGINLHAAKITTIGERAEDLFILTSDVGGRLDDDKQAELEIALVKNVARLSS
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: MIAB_MYCTU
Sequence: MSSASPLARCCDEATPSAGPRAAQPPYHGPVTSMVAHDAAAGVTGEGAGPPVRRAPARTYQVRTYGCQMNVHDSERLAGLLEAAGYRRATDGSEADVVVFNTCAVRENADNRLYGNLSHLAPRKRANPDMQIAVGGCLAQKDRDAVLRRAPWVDVVFGTHNIGSLPTLLERARHNKVAQVEIAEALQQFPSSLPSSRESAYAAWVSISVGCNNSCTFCIVPSLRGREVDRSPADILAEVRSLVNDGVLEVTLLGQNVNAYGVSFADPALPRNRGAFAELLRACGDIDGLERVRFTSPHPAEFTDDVIEAMAQTRNVCPALHMPLQSGSDRILRAMRRSYRAERYLGIIERVRAAIPHAAITTDLIVGFPGETEEDFAATLDVVRRARFAAAFTFQYSKRPGTPAAQLDGQLPKAVVQERYERLIALQEQISLEANRALVGQAVEVLVATGEGRKDTVTARMSGRARDGRLVHFTAGQPRVRPGDVITTKVTEAAPHHLIADAGVLTHRRTRAGDAHTAGQPGRAVGLGMPGVGLPVSAAKPGGCR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CECA_HYACE
Sequence: MNFSRIFFFVFACLTALAMVNAAPEPKWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAKG
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-A, Cecropin-C.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_THEMA
Sequence: MNRVVVGLQWGDEGKGKVVTYLSRYHDIVARFSGGANAGHTVNYGDFKVIHHLLPSADFTKNRGIAIGSGVLLDPQVLTEELRELKEKFPDYSGEIFISESAHVVLPVHKEMDRIIDEVLKIGTTKRGIGPACADRVMRVNVRVAELGNEEKLRYFLEKNLSLKKIYGVDFDAEKMMGDLSTFYETIKDFVVSPVQLKRILEEKSVLFEGTQGVLLDLDVGTYPYVTSMNCSSSGVSAGMGFPVEVDEVLGVFKAYTTRVGEGPFPTELTGEEGEKLRKAGHEYGSTTGRPRRCGWLDLPLLRYAIEISGVDSLVMTKADVLNGFEKIKVCVRYSDGRDLVSLRDLEKKEPVYEVFDGWKSLEDKNFERFVDFIERETGRPVRYISTGEKLEDIVEV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABY_ECOL6
Sequence: MSQLPGLSRETRESIAMYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAHHQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGVKRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQLQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWGLIWLMLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQMQVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE
What is the function of this protein?
Supports initiation of fatty acid biosynthesis in the absence of FabH.
What are the official names of this protein?
Probable acyltransferase FabY.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. FabY subfamily.
Protein: RS5_ACIET
Sequence: MAKFQPKVQSEGQDDGLREKMIAVNRVTKVVKGGRILGFAALTVVGDGDGRVGMGKGKSKEVPAAVQKAMEEARRNMVKVSLKNGTIHHNVTGHHGAAVVMMAPAPKGTGIIAGGPMRAVFEVMGITDIVAKSHGSSNPYNMVRATFDALTNSTTPAEVAAKRGKTVEDLFAA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: DER_CLOBL
Sequence: MGKPIVAIVGRPNVGKSTLFNKLAGKRIAIVQDTPGVTRDRIYAEAEWLNYKFTMIDTGGIEPKSEDIIVSQMRRQAQIAIEMANVIIFLVDGKEGLAPADEEVAQMLRKSKKPVVLVVNKIDKLKDENNAYEFYNLGIGDPVTISSSQALGLGDMLDRVVEYFKDDESDGEDDERINIAFIGKPNVGKSSLINKLLGEERLIVSDIPGTTRDSIDSYVDTEFGEFTLIDTAGLRRKSKVKEEIERYSVIRTYASIERADVCILMIDATEGISEQDQKIIGYAHDINKAILVIVNKWDLVEKDDKTMDKFKKELKVNLSFMPYAKYLFISAKTGQRIVKVLQTAKECYDNYTKRVKTGVLNDVISQAIMMKEPPIVGTKRLKIYYVTQIGTKPPTFIFFVNDPACIHFSYQRYLENQLRENFDFQGTGIKLEFRERKEK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: HIS6_VIBVU
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSAEDAARILEFGADKVSINSPALANPQLITDLADKFGVQCIVVGIDSYYDKETGKYQVYQFTGDEERTKATQWETRDWVQEVQKRGAGEIVLNMMNQDGVRNGYDIEQLNMVREVCKVPLIASGGAGAMEHFAEAYQKANVDGALAASVFHKQVINIGELKQYLKQQGIEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_NEIMA
Sequence: MEFSTKTEILQEQQAGAQLFVCTEEAQLNHPTALALLSSLEEGQNFADTKIPTGNGLQAVAVCCLKSTGRAALNKAAAEAAKWAQNQETVNVDVHAFEEAQAAAVAEAFAIAFGNAAYRFDRYKKEAKPAKFAEAVFHSAHEAAVKEALRVAEAQVYGQSLCRDLGNAAPNECTPEFLARTAKAEAEKLGAHAKIIEKDYIKENMGSFWSVAKGSVEDPYLVELSYFGAADKEAAPVVLVGKGITFDTGGISLKPGLNMDEMKFDMCGAATVISTFCAAVKLQLPINLIAVVATCENMPSGAANKPGDVVKSMKGLTIEVLNTDAEGRLILCDALTYAEQFKPKAVIDVATLTGACIVALGHDVSGVMGNNQDLVDSLLAASYNVDDKAWQLPLFETYKDQLKSNFADIPNIGTPGAGTITAATFLSYFTEGYPWAHLDIAGTAWKSGAEKGATGRPVPLLLNYLRNL
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRE1B_RAT
Sequence: MSGLSNKRAAGDGGSGPPEKKLNREEKTTTTLIEPIRLGGISSTEEMDSKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLQCYENQRELSSSGTEVPGCQEGLTRDVIPRTDPGTSDLREPLPMQFRAPLSEPALAFVVALGASSCEEVELQLQGRMEFSKAAVSRVVEASDRLQRQVEELCQRVYSRGDSEAPGEVARARTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSTETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSGSSTGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLASKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSSHCGPNLSHPDDSGLNALAPGKEDSGPGPGGTPDSKKELALVAGATSVASSVKKEELVSSEDDAQALAPGTQGLPSRGREPEARPKRELREREGPSLGPPPAASTLSRADREKAKAEEARRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRDLEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRVYIS
What is the function of this protein?
Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1).  H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively).  It thereby plays a central role in histone code and gene regulation.  The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory.  Required for transcriptional activation of Hox genes.
What are the official names of this protein?
E3 ubiquitin-protein ligase BRE1B, BRE1-B, RING finger protein 40, RING-type E3 ubiquitin transferase BRE1B, Syntaxin-1-interacting RING finger protein, Protein staring.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBC2_CANAL
Sequence: MSTPARRRLMRDFKRMQQDPPSGVSASPLPDNVMKWNAVIIGPSDTPFEDGTFRLLLSFDEQYPNKPPQVKFISEMFHPNVYASGELCLDILQNRWSPTYDVSSILTSVQSLLNDPNISSPANVEAANLYKDHRSLYVKRVRETVENSWNDDDDEEEEEEDEDEAEDEDDDDDDNIDED
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1.  H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.  Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 2, E2 ubiquitin-conjugating enzyme 2, Radiation sensitivity protein 6, Ubiquitin carrier protein UBC2, Ubiquitin-protein ligase UBC2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CH10_BRUA1
Sequence: MADIKFRPLHDRVVVRRVESEAKTAGGIIIPDTAKEKPQEGEVVAAGAGARDEAGKLVPLDVKAGDRVLFGKWSGTEVKIGGEDLLIMKESDILGIVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRSF1_HUMAN
Sequence: MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT
What is the function of this protein?
Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing.  Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF.  Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA.  Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC.  Binds preferentially to the 5'-CGAGGCG-3' motif in vitro.  Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing.  Isoform ASF-2 and isoform ASF-3 act as splicing repressors.  May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway.
What are the official names of this protein?
Serine/arginine-rich splicing factor 1, Alternative-splicing factor 1, ASF-1, Splicing factor, arginine/serine-rich 1, pre-mRNA-splicing factor SF2, P33 subunit.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus speckle. Note=In nuclear speckles. Shuttles between the nucleus and the cytoplasm (PubMed:12215544, PubMed:20308322, PubMed:9420331, PubMed:24449914). Nuclear import is mediated via interaction with TNPO3 (PubMed:24449914).
Protein: RLMN_LISMC
Sequence: MEKSSIYGLTWTKLTEWLEAHGQKKFRATQVWDWLYRKRVKTFEEMSNVPKETIELLTANFVMNTLEEQVVQESTDGTTKYLFKLSDGNLIETVMMKQEYGLSVCVTTQVGCNIGCTFCASGLLKKSRDLTAGEIVEQIMNVQHYLDGRNLEERVSHVVVMGIGEPFDNYDNVMDFLRVINHDKGLAIGARHITVSTSGLAPRIIDFANEDFQVNLAISLHAPNNELRTSIMRINKTYSIEKLMEAIHYYVNKTNRRITFEYIMLKGVNDHKKEALELAALLGEHRHLAYVNLIPYNPVDEHIDYERSTKEDVLAFYDTLKKNGINCVIRREHGTDIDAACGQLRSKQIKRVGVRERMKQKQAAAEE
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2062_LACPL
Sequence: MISKELLARINELAHKAKAEGLTELEEAERQELRQKYLKEFRAGFRQQVEMLQVYDKDGKEVTPEKVRQVQRDRGLRDD
What are the official names of this protein?
UPF0291 protein lp_2062.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1535_STRPI
Sequence: MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDSYKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK
What are the official names of this protein?
UPF0223 protein SPH_1535.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: LEPA_SYNAS
Sequence: MDHIRNFSIIAHIDHGKSTLADRLIQFTGISDERTFKDQMLDNMDIERERGITIKSQAITLPYQAKDGKTYSLNLIDTPGHVDFSYEVSRALASCEGVLLLIDAAQGVQAQTVANLYLAMEHNLEIIPVINKIDLPSADVERVIEQIDDELGLDSEGHLKCSAKAGIGIQDILEAIVKRVPPPRGNPEAPLAALIFDAHYDPFRGTIIHCRIMEGTVKSGDTIRFMSNSATYRVEEVGHFLLQREKRNCLSAGEVGYIIAGVKTVSDVRTGDTITLDDRPCSQPLPGFREVKPVVFASIYPIASDDYDDLKAALEKYQLNDASFIYQKDSSAALGQGFRCGFLGLLHLEVVQERLEREYDQSIILSVPSVRYRFTLKDGSVVYVDNPAHYPGSSSIELSEEPYIRATLMLPERYLGAVMKLCMEKRGVNSTLNYPSPGRVELLYEMPLAEVIYDFYDRFKSVTQGYGSFDYELIDYRESQLVLLDILVNGERVDALSQIVHRDRARARGLQACERLKEEIPRQMFKIAIQGAIGGEIISRTTITPFRKDVIAKCYGGDISRKRKLLEKQKKGKKRMKMIGQVSIPQSAFLSVLKSDAD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y0649_PARXL
Sequence: MSKSTDRINLTNQFLIAMPNMADPTFSGTVVYLCDHSERGALGLVINRPTDIDLQALFSRIDLKLEIEPLLHVPVYFGGPVQTERGFVLHDPKDGNAYTSSMSVPGGLEMTTSKDVLEAVASGTGPERFLLTLGHAGWGAGQLEEEISKNGWLTVEADPKIVFDVPAEERLEAALALLGINLSMLSGEAGHA
What are the official names of this protein?
UPF0301 protein Bxeno_A0649.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: UBID_CUPTR
Sequence: MQYKDLRDFIGQLEGLGELRRIARPVSPNLEMTEICDRLLRAGGPAVVFEQPAGAPHGDIYSVPVLANLFGTTRRVAFGMGAESMEDLRDIGRVLSALKEPEPPRGLREAGKLFTLAKSVWDMAPKRVSGPACQEVVWEGNDVDLARLPIQTCWPGDAAPLITWGLVVTKGPHKKRQNLGIYRQQVIGRNQVIMRWLAHRGGALDFREHALANPGKPFPIAVALGADPATILGAVTPVPDTLSEYQFAGLLRGSRTALAGCLTPTLSELSVPASAEIVLEGHIQPDPNHPSGYQHALEGPFGDHTGYYNEQDWFPVFTIDRITMRRDPIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFPEITDFYLPPEGCSYRMALVRMKKQYAGHAKRVMFGVWSFLRQFMYTKFIVVVDDDVDVRDWKEVIWAITTRVDPSRDTVLVDNTPIDYLDFASPVSGLGSKMGIDATDKWPGETTREWGTSIAMDAAVKAKVDTLWETLFERPAGR
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: WDR12_NEMVE
Sequence: MADVEQVQVRFFTKQKKYEIADTPFSLSANIGHGDLNDLINGLLGAGNVGQSIQFDFLIDSQYLQDTIQKHMKAKEISAESVVEIEYLEKHPAPQPDNILVHDDWVSSVSRCKNCIITGSYDNCVQIWDDQGSCLAKVKGHTSPVKDVEWVSKDEQKGVFLSSSQDQSIRVMEWSIGSGEASCVHVCKGHTQSVDSISINPSATKFCSGSWDKTLKLWSAVVNPEGGDEGENGSLSKKQKTTGVKKKATTRTPLMTFTGHTQAVSSVVWMDRTTICSAGWDHCIRLWDAESGVNKQTLTGSKVFCEIAYSALNQCLASGSADKYIRLWDHRAEDGQVVRGILTSHQGWVSSVSWSPSNQFELASASYDTTVKIWDTRSPYTPLYTLTGHQDKVMCVRWSSSRHLMSGGTDNQLILY
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein WDR12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: NFYB1_CAEEL
Sequence: MDPKPINEGMLLEDHDHGMPEEEEITEDDMNGIHNIEEDTRTISEIAMELHHPNKSQVLLDQERFLPIANVVRIMKTQMDPQAKLAKDAKECAQECVSEFISFIASEAAEICNITKRKTITADDLLTAMEATGFDNYAEPMRIFLQKYRQAHKITGPIHRTHPDYVRPPQFQMDPFVRPLFFDTEQGRRCTETQYVINGSEIVKNAPLGEEWNEQTGTLNTRADGYYMEEPMEPMPMEEVEIEEHEEIIEQDSLGAIALEQQGQMQIYVDPKTKQHFAAKETPNGMELYPLIIQDTPLQLENVSGPNQFVMNMPDGRAIPHGMGQEEPQPVSSSSVMRKIGQNPSSYAQQHHHVSHVEQHDDVEYEEEEEVDQVEEDTVPVPIAPRPAATRVQPKRTPTKRKK
What is the function of this protein?
Component of sequence-specific heterotrimeric transcription factor (nfya-1-NF-Y and nfya-2-NF-Y) complexes which specifically recognize a 5'-CCAAT-3' box motif found in the promoters of its target genes to regulate their expression and control cellular identity in particular tissue types (PubMed:17574230).  In association with the components in the NF-Y complexes, represses the expression of the T-box transcription factor tbx-2 throughout larval development, which most likely restricts its expression to certain tissues (PubMed:23933492, PubMed:25873636).  May act to repress txb-2 expression in conjunction with tbx-2 itself, which has an autoregulatory role (PubMed:25873636).  In association with the components in the nfya-1-NF-Y complex, negatively regulates the expression of the homeobox protein egl-5 to spatially restrict its expression in tissues such as the head (PubMed:17574230).  May regulate spatial egl-5 expression in association with the mes-2-mes-3-mes-6 complex (PubMed:17574230).
What are the official names of this protein?
Nuclear transcription factor Y subunit nfyb-1, CAAT box DNA-binding protein subunit nfyb-1.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Perikaryon. Note=Localizes to the cytoplasm of secretory cells and cell bodies of the small ganglia surrounding the pharynx.
Protein: YUSZ_BACSU
Sequence: MNKKIAIVTGASSGFGLLAAVKLARSFFVIATSRQPEKAEQLRELAAAHNVSDSIHITALDVTDEQSIVSFGKAVSAYAPIDLLVNNAGTAYGGFIEDVPMEHFRQQFETNVFGVIHVTKTVLPYIRKHGGAKIINVSSISGLTGFPALSPYVSSKHALEGFSESLRIELLPFGIETALIEPGSYKTSIWSTSLSNFMSVPADDSAYHQYYKKILSYVQKNGEESGDPQEVADLIYQLATKQHIKNLRYPIGKGIKLTLLFRSLFPWSAWESILKKKLFS
What are the official names of this protein?
Uncharacterized oxidoreductase YusZ, ORFA.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: STP5_ARATH
Sequence: MAGGGLALDVSSAGNIDAKITAAVVMSCIVAASCGLIFGYDIGISGGVTTMKPFLEKFFPSVLKKASEAKTNVYCVYDSQLLTAFTSSLYVAGLVASLVASRLTAAYGRRTTMILGGFTFLFGALINGLAANIAMLISGRILLGFGVGFTNQAAPVYLSEVAPPRWRGAFNIGFSCFISMGVVAANLINYGTDSHRNGWRISLGLAAVPAAIMTVGCLFISDTPSSLLARGKHDEAHTSLLKLRGVENIADVETELAELVRSSQLAIEARAELFMKTILQRRYRPHLVVAVVIPCFQQLTGITVNAFYAPVLFRSVGFGSGPALIATFILGFVNLGSLLLSTMVIDRFGRRFLFIAGGILMLLCQIAVAVLLAVTVGATGDGEMKKGYAVTVVVLLCIYAAGFGWSWGPLSWLVPSEIFPLKIRPAGQSLSVAVNFAATFALSQTFLATLCDFKYGAFLFYGGWIFTMTIFVIMFLPETKGIPVDSMYQVWEKHWYWQRFTKPTST
What is the function of this protein?
Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.
What are the official names of this protein?
Sugar transport protein 5, Hexose transporter 5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.