PharMolix/UniProtQA huggingface dataset:
Protein: LGB3_SOYBN
Sequence: MGAFTDKQEALVSSSFEAFKTNIPQYSVVFYTSILEKAPVAKDLFSFLANGVDPTNPKLTGHAEKLFGLVRDSAGQLKASGTVVIDAALGSIHAQKAITDPQFVVVKEALLKTIKEAVGDKWSDELSSAWEVAYDELAAAIKKAF
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin C3.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: MYG_LYCPI
Sequence: MGLSDGEWQIVLNIWGKVETDLAGHGQEVLIRLFKNHPETLDKFDKFKHLKTEDEMKGSEDLKKHGNTVLTALGGILKKKGHHEAELKPLAQSHATKHKIPVKYLEFISDAIIQVLQNKHSGDFHADTEAAMKKALELFRNDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TRHO_AGRFC
Sequence: MTDTTILPRPEVSGDFLVAALYHFARLPRFESLREQLFELCQKNGVKGTLLLAAEGINGTIAGPDAGVQAVLSFLRAQPEFAALEHKESRASHMPFVRLKVKLKKEIVTMGVPDIDPNRIVGTYVDPRDWNALISDPDTIVIDTRNDYETAIGVFKGAVDPQTKTFREFPDWVKNNPGLHNKPKIAMYCTGGIRCEKATAFMKEQGFDEVYHLKGGILKYLEEVPEEESLWEGACFVFDERVSVVHGLAEGDHQLCHACRNPITPDVRLSPKFEEGVSCPSCYDERSEDDRQRFRDRQQQIELAKTRGERHLGR
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: YEEX_SALPB
Sequence: METTKPSFQDVLEFVRLFRRKNKLQREIQDIEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKSDYEDRVDDYIIKNAEISKERRDISKKLKAMGEMKHADVKAE
What are the official names of this protein?
UPF0265 protein YeeX.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: NSCC_ARTOC
Sequence: MAKPQATVLIIGAGISGLTTSRLLTNSGIPNIVFEASTPDRSQGFAISLQEFGYSALLSALGDLPLSSLIRGVAPDREIGGTGWIDQALRDNCTGELLVAPDLTTAKQTVVRANRNALRRWIADCGEEELDVRYGHKLQSVEGTVGDITAVFENKARYRGSLVVAADGVNSTIRSQVLPGVVPETIPLIHYHGEFQLSRTAFDELIRPHSGHSNILVGVGDGFNTPLSICNMTKTQVHLDWSYSRTVTGDDDLLYRPNLPSEEAKQIPPALVKELAALALAEPWKRFLNPESLKSHRVFHWTTRCVYMTQDDARRAGEQGVVFVGDSWHAMPIFGGEGGNHALLDGVELADAVVKVVASPGKDHLSKAVASYYAGAWKRSQEAVRRSTQRFFLLHRPAAEWKEIAEKKKKAV
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of neosartoricin B, a prenylated anthracenone that probably exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576, PubMed:23368997).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (By similarity).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (By similarity).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (By similarity).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (By similarity).  Neosartoricin B can be converted into two additional compounds neosartoricins C and D (By similarity).  Neosartoricin C is a spirocyclic compound that is cyclized through the attack of C3 hydroxyl on C14, followed by dehydration (By similarity).  On the other hand, neosartoricin D is a further cyclized compound in which attack of C2 on C14 in neosartoricin C results in the formation of the acetal-containing dioxabicyclo-octanone ring (By similarity).  Both of these compounds are novel and possibly represent related metabolites of the gene cluster (By similarity).
What are the official names of this protein?
FAD-dependent monooxygenase nscC, Neosartoricin B biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: LIFO1_BURCE
Sequence: MTARGGRAPLARRAVVYGAVGLAAIAGVAMWSGAGRHGGTGASGEPPDASAARGPAAAPPQAAVPASTSLPPSLAGSSAPRLPLDAGGHLAKARAVRDFFDYCLTAQSDLSAAGLDAFVMREIAAQLDGTVAQAEALDVWHRYRAYLDALAKLRDAGAVDKSDLGALQLALDQRASIAYRWLGDWSQPFFGAEQWRQRYDLARLKIAQDPALTDAQKAERLAALEQQMPADERAAQQRVDRQRAAIDQIAQLQKSGATPDAMRAQLTQTLGPEAAARVAQMQQDDASWQRRYADYAAQRAQIESAGLSPQDRDAQIAALRQRVFTKPGEAVRAASLDRGAGSAR
What is the function of this protein?
May be involved in the folding of the extracellular lipase during its passage through the periplasm.
What are the official names of this protein?
Lipase chaperone, Lipase activator protein, Lipase foldase, Lipase helper protein, Lipase modulator.
What is the protein family that this protein belongs to?
Belongs to the lipase chaperone family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: YABA_BACC2
Sequence: MEKKDIFESVSSMEEQIGHLYKQLGELKQHLAELLEENQHIKMENNNLRHRFEEVQNKEKQKTQKRKEVKPKTDIGEGYDNLARLYQEGFHICNLHYGSVRKEGDCLFCLSFLNKK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: MENH_SHISS
Sequence: MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLYVYLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILNFWLVGYSLGGRVAMMAACQGMPGLCGVVVEGGHPGLQNAEQRAERQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: FAC8_MYCTU
Sequence: MSTAGDDAVGVPPACGGRSDAVGVPQLARESGAMRDQDCSGELLRSPTHNGHLLVGALKRHQNKPVLFLGDTRLTGGQLADRISQYIQAFEALGAGTGVAVGLLSLNRPEVLMIIGAGQARGYRRTALHPLGSLADHAYVLNDAGISSLIIDPNPMFVERALALLEQVDSLQQILTIGPVPDALKHVAVDLSAEAAKYQPQPLVAADLPPDQVIGLTYTGGTTGKPKGVIGTAQSIATMTSIQLAEWEWPANPRFLMCTPLSHAGAAFFTPTVIKGGEMIVLAKFDPAEVLRIIEEQRITATMLVPSMLYALLDHPDSHTRDLSSLETVYYGASAINPVRLAEAIRRFGPIFAQYYGQSEAPMVITYLAKGDHDEKRLTSCGRPTLFARVALLDEHGKPVKQGEVGEICVSGPLLAGGYWNLPDETSRTFKDGWLHTGDLAREDSDGFYYIVDRVKDMIVTGGFNVFPREVEDVVAEHPAVAQVCVVGAPDEKWGEAVTAVVVLRSNAARDEPAIEAMTAEIQAAVKQRKGSVQAPKRVVVVDSLPLTGLGKPDKKAVRARFWEGAGRAVG
What is the function of this protein?
Catalyzes the activation of medium/long-chain fatty acids as acyl-coenzyme A (acyl-CoA).
What are the official names of this protein?
Medium/long-chain-fatty-acid--CoA ligase FadD8, FACL8.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: PNCB_BRASB
Sequence: MTVTDIASRTYNHGWRLDPIVRSLLDTDFYKLLMLQMIREFYPDQKVTFSVINRTKRVRLGDVIDEGELRAQLDHARTIRFTKKELIWLAGNTFYGKTHMFSPDFLAWLAHFRLPDYELHKADGQYELHFHGPWTHTTMWEIPALAIVNELRSRQAMKGQGRFALDVLFARAKAKLWAKVERLRRLEGLRLSDFGTRRRHGFLWQRWCVEAVKEGLGPSFTGTSNVLLAMDNDLEAIGTNAHELPMVAAALARDDDELRFAPYRILDQWRQTYAGNLLIALPDAFGTKAFLRDAPDWVADWTGFRPDSAPPIEAGEEIIAWWKSKGRDPKQKLLVFSDAMDVESIEQIHHRFSDRVRLSFGWGTNLTNDFVGCAPDGSVDLDPISLVCKVTSVDGQPAVKLSDNPEKATGDPAEIARYLRVFGDAGRVRTPVVV
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: TATB_MYCSJ
Sequence: MFANIGWGEMLILVIAGLVILGPERLPGAIRWTSNALRQARDYVSGATTQLRQDFGPEFEDLREPITELQKLRGMTPRAALTKHLLDGDDSFFTGKFDQQNGKPAAGQEKPVTPVNPPVTATPPSESTATPFDSDAT
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: LPXK_BURM1
Sequence: MSAAGGLLARLETRVTREWQRRSAFAWALTPFACAFGLCAALRRTAYARGWKQAVDVGVPVVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGANVKTPTAVTPASRAGAAGDEPLLIARRTGAPVWVCPDRVAAAQALRAAHPDVDVIVSDDGLQHYRLARTVELVVFDHRLGGNGFLLPAGPLREPLSRHRDATLVNDPYSGALPPWPDTYSLALTPGAAWHLDQPTLRRPLSQFANERVLAAAGIGAPERFFATLRAAGLAPATRALPDHYAFADNPFVDDAVDAILITEKDAVKLGASWRDARLWVVPVEAALDPRLIALVVEKLRGRSPA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: STING_DANRE
Sequence: MSVMGEDALVPRARSRLPVMCAAGLGFLTLAVAWLLDSDKFSERAGIIAFGLMLERFIYCICLLAEELLFHSRQRYHGRMSEIFRACFRGSGILGMCAIFLMLMLGGVSFSVKQWSHFNLMCAGYMLLNSLGVLGPAPVEISEICEAKKMNVAHGLAWSFYIGYLKFLLPALEVNVREYSRRERLSSPRLHILLPLNARVPSKPEEEDTNVVFHENLPDLKLDRAGVRKRSYTNSVYKITHNNETFSCILEYATPLLTLYQMSQESSAGFGERERKQQVLLFYRTLSQILDNSLECRNRYRLILLNDEHTGDPHYLSRELFQNLKQQDGEIFMDPTNEVHPVPEEGPVGNCNGALQATFHEEPMSDEPTLMFSRPQSLRSEPVETTDYFNPSSAMKQN
What is the function of this protein?
Facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon (IFN-alpha and IFN-beta) (PubMed:23091644).  Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm (PubMed:23091644).  Acts by binding cyclic dinucleotides: recognizes and binds cyclic di-GMP (c-di-GMP), a second messenger produced by bacteria, and cyclic GMP-AMP (cGAMP), a messenger produced by CGAS in response to DNA virus in the cytosol (By similarity).  Upon binding of c-di-GMP or cGAMP, STING1 oligomerizes and is able to activate both NF-kappa-B and irf3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state (PubMed:30842662).  In addition to promote the production of type I interferons, plays a direct role in autophagy (PubMed:30842662).  Following cGAMP-binding, STING1 buds from the endoplasmic reticulum into COPII vesicles, which then form the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).  The ERGIC serves as the membrane source for LC3 lipidation, leading to formation of autophagosomes that target cytosolic DNA or DNA viruses for degradation by the lysosome.  The autophagy- and interferon-inducing activities can be uncoupled and autophagy induction is independent of TBK1 phosphorylation.  Exhibits 2',3' phosphodiester linkage-specific ligand recognition: can bind both 2'-3' linked cGAMP and 3'-3' linked cGAMP but is preferentially activated by 2'-3' linked cGAMP (By similarity).
What are the official names of this protein?
Stimulator of interferon genes protein, STING, Transmembrane protein 173.
What is the protein family that this protein belongs to?
Belongs to the STING family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note=In response to double-stranded DNA stimulation, translocates from the endoplasmic reticulum through the endoplasmic reticulum-Golgi intermediate compartment and Golgi to post-Golgi vesicles, where the kinase tbk1 is recruited. Upon cGAMP-binding, translocates to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) in a process that is dependent on COPII vesicles; STING1-containing ERGIC serves as a membrane source for LC3 lipidation, which is a key step in autophagosome biogenesis.
Protein: ATPG_BACCN
Sequence: MASLRDIKAKINSTKKTSQITKAMEMVSASKLNRAEQNAKSFVPYMEKIQEVVASIAQGSKGINHPMLTARPVKRTGYIVITSDRGLAGGYNSNVLREVSKVIRERHNMDPNQYSIIVLGRLGRDYLKRRGFNIIDEVVGLSDHPSFTDIKDLASRAIAMFADGAYDELYIYYNHYVSKISQEVTENKVLPLTDVKSDKKLTPYEFEPSEEEILKVLLPQYAESLVYGALLDGKASEHAARMTAMKSATDNAMEVIDTLTLSFNRARQAAITQEITEIVGGAAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NR1H2_RAT
Sequence: MSSPTSSLDTPLPGNGSPQPSTSSTSPTIKEEGQETDPPPGSEGSSSAYIVVILEPEDEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVHGGAGRYACRGSGTCQMDAFMRRKCQLCRLRKCKEAGMREQCVLSEEQIRKKKIQKQQQQQPPPPTEPASGSSARPAASPGTSEASSQGSGEGEGIQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPSRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
What is the function of this protein?
Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (By similarity).  Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4).  Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8.  Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).  Induces LPCAT3-dependent phospholipid remodeling in endoplasmic reticulum (ER) membranes of hepatocytes, driving SREBF1 processing and lipogenesis (By similarity).  Via LPCAT3, triggers the incorporation of arachidonate into phosphatidylcholines of ER membranes, increasing membrane dynamics and enabling triacylglycerols transfer to nascent very low-density lipoprotein (VLDL) particles.  Via LPCAT3 also counteracts lipid-induced ER stress response and inflammation, likely by modulating SRC kinase membrane compartmentalization and limiting the synthesis of lipid inflammatory mediators (By similarity).  Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex (By similarity).
What are the official names of this protein?
Oxysterols receptor LXR-beta, Liver X receptor beta, Nuclear receptor subfamily 1 group H member 2, Orphan nuclear receptor OR-1, Ubiquitously-expressed nuclear receptor, UR.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL15_TROW8
Sequence: MRLIKLHHLRPAPGSRRARIRVGRGEGSKGKTAGRGTKGTKARAPVRPGFAGGQIPLHMSIPKLKGFKNHKKVEYSVISIKRLCEAYPSGGVVTRDNVMSVIGKKRGFVKLLSDGEVTVKFDITVDKASAAAVEKITSAAGTVTQAR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SRB8_DEBHA
Sequence: MSKTKNRNSLLSSHNRTSVSNSTKDELLAMKYVMDKPAIPLYPLNELSNSSESISEQNRYTSNSSTDELTYPDFKPWKDTTHLPKGKSEVEVEKLNNEAYLNKGYFEGPSVANEYYSARNLIQASLFSSSSNCDKVLKELSQHLVNSYRTRNEVINKIKYNSNKFKIPPRVTLTASKKEAWLRDLANPDEPLSNISNKLPHGIKNKMLVDILCSKNIPTSRALWLTKCVLYSELLVLKKKYQSRLPNNPHPVENTTSETFETQWLQEWTHQLVDYFYKFSKDMCNITIQEKKQVYLTKLNYLLNYVQALYIECLLDKSFFLTSILKFLKEGLPLDQSHVSELLAFSRSEGEESSLDKWLVDIDLNYGQRLISITLVKMFWKDILELDYLSKELSELLLLNYYFIERIPTYNTKSSNYSHKQNHTAALSSTLKLKLLSSISDTVNYLFKHNTNVFIIPNYWILVNETLYKILLSDVANSYDSEEQTEIRKQLKLIKYRNESLMLSMKDVQSSNFVDVNTARNLAKDRRRSNSLQQSLSQDTKNNYNSITGKKIPNTVENDNYFINRNSDDTLNIIDQLDRLKLNDTLAEMLIPSSISSSPDNFNDWRVNLKVVIYWAITIYREQMSSSEGILIICNFLKRKVLQNISVKNVNSIKAEFENEILEIIYNLAHCTDVDIIDYNLYVLINELYQLKVITISSYLRKLIASGLFYVSPSADGAQSHNENNSSVETHLAILQNLPVLNNKQCDSILRKWTPNGFNFEEKFEKGKLILKEELVDRLMSNSFDGYCDEKLTYIKNLKVGLKFLLVNWLTNYLKTSITKSPKLIHINPNIITSLYNFYALCDNLTVFFKVLIKFILRNEGKVIICYMDSLYLISKLIIRHFKLVKFIAGKSYESTTTGYELFKLIILNYKDLSTRDNDYYNFSDVWYFIDNAVEKNEPTYGKSSDGNNDNALKHKNFNQLLFAKETVDSPMRIHANSNTPQKNNDSYTATVFRNDLDLLLEAPIKLLNNTDITDFISTLELNVSNEAFNEISNTEESVIIIMEYYFKNIGEFTELHENLCMRLLINSKRSLDMTTRGIFFDIMKHFIINLVRTKPGIEKLITLFKKLMCFEVYQPHELFSTLRSILPRELSHEQMDALKYELLFGNPESDNKNLFNDQALVLRCIRYLYVKRHSNDVFITLLDSFSNEKETFFNSYALKAYNSKVLSFFRQFSISNTKFFMDGLSKVASNSDIISFLNLLIYISEEPIGSSSDLPRLASIIDEFNLPVCQVLIKIIIMNELRDSNKDKSIEKLRYILDMLLNNLKFHFVSYNSYFGELFNYLSWEHKLNILSIFEHNFLCNTEFIVSDDKFTENSVCLMSSDGRTNLLSILKDYFKKFSVSSLNTVTTSKEVFHNLSKFLLKVLQLANADIIGDSRRDAYNTISIFLRILIIHKLSLTSMIIEQDGQDLHFIKNLIALLESKFLCFNNEKLRILLYDLLLLMKSSITSSMILNPDSNLADDMTTDTSHQQHSPSNDYLSRSNPDGTEVGNSNSKYFGVSNISTIPNLSSVFNISEPNISYPLKKYTDDSKILCALMLEESELQKGGDIYALNDSKLILLPSRREALSSAFDILNETQQTVSKKRFKIESYELLEDTGIELNNGCINLSLFDAFTTKENPP
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 12, Mediator complex subunit 12.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECR_CHLCV
Sequence: MLKYPDYLSKLISLLRKLPGIGFKTAEKLAFELLDWDQDQLEAMGQAFSEVSAARSHCSTCFCLKNLPESNCEFCQNNRDTSTLCIVATPKDIFSLERSQIFKGHYYVLGTLLSPITGKHIDVERIGLLKQRIEFLKPQEIILALDATLEGDATALFLKQELAFSSASISRLALGLPIGLSFDYVDSGTLARAFSGRNPY
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: SRE8_CAEEL
Sequence: MCSPSTSDVRFITFVNTTYIEAEGLEAIFDLLLKIEVGFLVFSWIEFLYLFYLFIFIRSMHFNLTFLFMNYGGQYFCSMLSRCIIVYQQLGNDPNNDLHNWILVANFARTVCLFIAMYILPIFMIERCLASFFVKNYEKSRKIWVSLMILSIFHPLVFASAIAYIQCWIPVVVHVISFFIVNIIGYIGIHICYSYNIKKHRKFYSPQCISRVTYGLSERFQLAENIKMCKVLKKVQISILFFNIGCCSILLMDHFQVKMMIIYWSYVCFNFFALVYGITVPIILYSALPEWQKETRRLLNLCIGRRNVGEEPKSTFGEQMIYNDHAIESNIYFTQFNKTTH
What are the official names of this protein?
Serpentine receptor class epsilon-8, Protein sre-8.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sre family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DLTD_STAA8
Sequence: MKLKPFLPILISGAVFIVFLLLPASWFTGLVNEKTVEDNRTSLTDQVLKGTLIQDKLYESNKYYPIYGSSELGKDDPFNPAIALNKHNANKKAFLLGAGGSTDLINAVELASQYDKLKGKKLTFIISPQWFTNHGLTNQNFDARMSQTQINQMFQQKNMSTELKRRYAQRLLQFPHVHNKEYLKSYAKNPKETKDSYISGFKENQLIKIEAIKSLFAMDKSPLEHVKPATKPDASWDEMKQKAVEIGKADTTSNKFGIRDQYWKLIQESKRKVRRDYEFNVNSPEFQDLELLVKTMRAAGADVQYVSIPSNGVWYDHIGIDKERRQAVYKKIHSTVVDNGGKIYDMTDKDYEKYVISDAVHIGWKGWVYMDEQIAKHMKGEPQPEVDKPKN
What is the function of this protein?
Involved in the D-alanylation of lipoteichoic acid (LTA).  Could be responsible for the transfer of DltC-carried D-alanyl groups to cell membrane phosphatidylglycerol (PG), or alternatively of D-alanine residues from D-Ala-undecaprenol phosphate to the poly(glycerophosphate) chains of LTA.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
Protein DltD.
What is the protein family that this protein belongs to?
Belongs to the DltD family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein; Extracellular side.
Protein: WEFC_STROR
Sequence: MNKIDFVVTWVDGGDPIWQAKKAKYSGAVDTSKNSMNSVKAYRDWGTFKYWFRGVEKFAPWVNKVYLVTDQQKPSWLDINSEKLVLVDHTEIICNDYLPVFSANPIESNIHRIPGLSEHFVFFNDDMYLTAPVEPTDFFSEDGLPKYNTALSPIIPERYGTGNFQVNDMEIVTSYFSRNEILKNGQFFDPKQGLKSIVKSLLYRNSQFICGFWESHLPYPLLRSTMNLVWEKEKAVLERTSASRFRNPSDTNVWLFKYWQIASGKYAIGNPKLGGLFSLDNAGPDFWKILNSGKYQIMCINDGFNIQDEEQVMTDFIKAMDQLLPDRSSFEI
What are the official names of this protein?
Receptor polysaccharide phosphotransferase WefC, Stealth protein WefC.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: HTPX_ACIAD
Sequence: MMRIGLFLLTNLAVLVVAGIILSLFGVGSYHGAGGLNLGNLLVICFVFGMVGSLISLLMSKWMAKKTTGTEIIDPNAPRNQAEAWLLQTVAELSQRAGIQMPEVGIFPSYQSNAFATGWNKNDALVSVSTGLMERMNKDELRAVLAHEIGHVANGDMVTLALIQGVVNAFVMFFARVVGDFIDRNVFGRQDGEAPGMGYFAITIVLDIVFGILASAIVMWFSRHREYRADEAGARLAGKQAMISALLRLQAESEMPDQMPKEMKAFAIAEGKEQGFSLAALFQTHPSIEQRVAALQQLNCP
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YHIT_MYCGE
Sequence: MEKNTTSSCIFCDIVQGSITSYKIGENEHAIAFLDAFPVADGHTLVIPKKHAVDFSSTDQKELQAVSLLAKQIALKLKMTLKPSGLNYVSNEGAIAGQVVFHFHLHIVPKYETGKGFGYNVNKTNKRSLEENYQLISESKN
What are the official names of this protein?
Uncharacterized HIT-like protein MG132.
Protein: ANMK_BORPA
Sequence: MDSTTHGPRTHVPGRLFIGLMSGTSMDGADGVLVRLDGPRPEVLASASLPMPAALRDELFALNHAGANELERAALAANGLARLYARAVRQLLDQAGLQPGDVAAIGAHGQTVRHRPDLGYTLQLNAPALLAELAGIDVVADFRSRDVAAGGQGAPLVPPFHAALFAGGQARAVLNLGGIANVTLLEPGRPPRGFDTGPANVLLDAWCQRHTGQPYDADGRFAAQGQVLAGLLEHLIASEPWFALAPPKSTGRDLFNLDWLLARLQAFDGPAPQPQDVQATLQRLTARTVANAIDASAAAPRDVLVCGGGARNPGLMRELAYCLQRPVHPTDDAGVPAQWVEALAFAWLAQACLDRIPAGLPTVTGARAARVLGALYPA
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: CHEY_ECOL6
Sequence: MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGLDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation (By similarity).
What are the official names of this protein?
Chemotaxis protein CheY.
What are the subcellular locations of this protein?
Cytoplasm.