PharMolix/UniProtQA huggingface dataset:
Protein: ENO_PECCP
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQAVVGKDAKDQANIDKIMIDLDGTDNKSKFGANAILAVSLAAAKAAAASKGLPLYAHIAELNGTPGKYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEAIRMGSEVFHTLAKVLKSKGMGTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEDLTKQYPIVSIEDGLDESDWAGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGDSAPFNGLKEVKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: AUSE_EMENI
Sequence: MGSATPSRLQKFPATAPADEIYAAFKEDGCVIIEGFVPPDQMARFSQEIQPAMEKIQVQVTNDGNSNDRVKRFSKLVTTSPTFRHEILENDLMHELLQRVFSKPGEGMGYHFNDTMVIEVQPGAPAQRLHRDQELYPWWNSMGPDAPECLVNFFCAVTPFTVENGATRLVPGSNRWPELTLINATDCPQYGKIDSVPAIMQPGDCYMMSGKVIHGAGHNATLSDQRRALAFSTIRRELRPVQAFPLWIPMQIATELSPRTQAMFGFRSSTQHCDVDTVHFWGNDGKDIGEHLGLISSA
What is the function of this protein?
Multifunctional dioxygenase; part of the gene cluster B that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids (PubMed:22329759).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (PubMed:22329759).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (PubMed:22329759).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (PubMed:22329759).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (PubMed:22329759, PubMed:23865690).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (PubMed:22329759).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (PubMed:22329759).  Finally, the cytochrome P450 monooxygenase ausG modifies austinolide to austinol (PubMed:22329759).  Austinol can be further modified to dehydroaustinol which forms a diffusible complex with diorcinol that initiates conidiation (PubMed:22234162, PubMed:22329759).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end products of the Emericella nidulans austinoid biosynthesis clusters are austinol and dehydroaustinol, even if additional enzymes, such as the O-acetyltransferase ausQ and the cytochrome P450 monooxygenase ausR are still functional (PubMed:29076725).
What are the official names of this protein?
Multifunctional dioxygenase ausE, Austinoid biosynthesis clusters protein E.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: DNAA_LARHH
Sequence: MTDLSAFWPQCLARFEAELSAQQFNTWIKPLVCVAGEDAIALYAANRFSLGFVKERFLSRIETFAEDILGRPVTIELRIGGAQAGASAPAAASPRSPGRPAPAPVAATPTTGSLADSIVSDVPLPNVKLTAPKPAIGGGHESTRLNPAFTFESLVTGKGNQLARAAALQIADNPGDSTYNPFFVYGGVGLGKTHLIQAIGNHVYQKNPQAKIRYIHAERYVADIMRAYQHKAFDEFKRYYHSLDLLLIDDIQFFAGKNRTMEEFFYAFNALLEGGKQVIMTCDSYPKQIEGMDERLISRFSWGLTVEIQPPELEMRVAILMKKAEADNLKLGNDVAFFIAQNVRSNVRELEGALKRVVAYSRFSNQPISLDLVKEALKDILAAGNRQISVDNIQKTVADYYKIKLSDMHSKKRSRDIARPRQVAMALAKELTSMSLPNIGDAFGGRDHTTVLHACKTIAEMRESDPDISRDYAALQQMLRN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_RHOE4
Sequence: MARLSGVDLPREKRMEIALTYIYGIGRTRSKEILDATGVSPDLRSKDLSDEDLAKLREYIEESLKVEGDLRREVQADIRRKIEIGCYQGLRHRRGLPVRGQRTKTNARTRKGPKRTIAGKKKAK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RPOE_STAA1
Sequence: MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALGDYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILDADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDELDEDEEVFEDEEDFND
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: YK25_YEAST
Sequence: MSNSHHTSQGRRNKLSVWVKKIINTTTTTNASVSSSKPRRGTRAGPTRVKRAELDPDGTTISSSLRPLVDRNSLHSSESDDEGDRRVAWDEPPTGKVRQQQQQQQQQQNDNASVIPLVSFCSSSVKSSTFSDIHSIQSTRPTIFSNRTFETNSSVLAIPPQSILDRSRTLPPSNASNTTTRRP
What are the official names of this protein?
Uncharacterized protein YKR045C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_PINCU
Sequence: MDEFHRCGKEDSFWQQCFLYPLFFQEDLYAISHDHYLDVSSSSRPMEHLSSNDQLSFLTVKRLIGQIRQQNHSIVLFVNCDPNPLADRKKSFYSESVLEALTLVLEVPFSIWSKYSVEGMNESKSFRSIHSIFPFLEDKFPHSNSILDARIPYSIHPEILVRTFRRWIRDAPSLHPLRSVLYEYRNSPDNLQRSIIVVPRVNTRFFLFLWNYYVCECESILFSRLKRSSHSRSLSHGSFPQRTHFHRKIKHIIIFSRRNSLKSIWSLKDPKIHYVRYGERPIIAIKGAHLLVKKCRYYLLIFRQFYFHLWSEPYRVCSHQLSKNCSSSPGYFLRVRMNPILVRTKMLDELFIADLITDEIDPIVPIVPIIGLLATEKFCDISGRPISKLSWTSLTDDDILDRFDQIWRNLFHYYSGSFDRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFKKSFSKEREFYSLRFSSKAAARSQRERIWHSDIPQINPLANSWQKIQDLKIENLFDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RBSA_HAEIN
Sequence: METLLKISGVDKSFPGVKALNNACLSVYAGRVMALMGENGAGKSTLMKVLTGIYSKDAGTIEYLNRSVNFNGPKASQEAGISIIHQELNLVGNLTIAENIFLGREFKTSWGAINWQKMHQEADKLLARLGVTHSSKQLCAELSIGEQQMVEIAKALSFESKVIIMDEPTDALTDTETEALFNVIRELKAENRGIVYISHRLKEIFQICDDVTVLRDGQFIGERVMAEITEDDLIEMMVGRRLDEQYPHLSQEKGECVLDVKHVSGSGIDDVSFKLHAGEIVGVSGLMGAGRTELGKLLYGALPKTAGKVRLKNQEIENRSPQDGLDNGIVYISEDRKGDGLVLGMSVKENMSLTSLDHFSQKGGIRHQAEKMAVDDFILMFNIKTPNRDQQVGLLSGGNQQKVAIARGLMTRPNVLILDEPTRGVDVGAKKEIYQLINEFKKEGLSILMISSDMPEVLGMSDRVLVMREGKISAEFSREEATQEKLLAAAIGK
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PADR_BACSU
Sequence: MRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPELKKLTDEGFITFRTTIQGTKLEKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKAYFISCLSRQEASDLFKDQLQKRQAKLSDLQGSYEKLMASAEPMSFSSPDFGHYLVLTKALEREKNYVSWLESILAMIDKD
What is the function of this protein?
Negative transcriptional regulator of padC phenolic acid decarboxylase.
What are the official names of this protein?
Negative transcription regulator PadR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_FUSNN
Sequence: MNVYDIIKKPVVTEKTELLRKEYNKYTFEVHPKANKIEIKKAVEAIFNVKVEDVATINKKPITKRHGMRLYKTQAKKKAIVKLAKENTITYSKEV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: 3SA3_NAJKA
Sequence: LKCNKLIPLAYKTCPAGKNLCYKMFMVSNKTVPVKRGCIDACPKNSLLVKYVCCNTDRCN
What is the function of this protein?
Heterodimer: has no cytolytic activity, but retains most of the alpha-cobratoxin capacity to compete with alpha-bungarotoxin for binding to Torpedo and alpha-7/CHRNA7 nicotinic acetylcholine receptors (nAChRs) as well as to Lymnea stagnalis acetylcholine-binding protein.
What are the official names of this protein?
Cytotoxin 3, CX3, Toxin CM-7.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: COBQ_STRSV
Sequence: MVKALMVQGTASDAGKSIIAAGLCRIFKQDGLEVVPFKSQNMALNSFITKKGDEMGRAQVVQAEAAGKEPDVRMNPVLLKPTSDRKSQVVFLGRVLRDMDAVEYHEYKQQLLPKIKEVYDELGAENDIIVIEGAGSPAEINLNDRDIVNMGMAKLVDAPVILVADIDKGGVFASIYGTIELMPPEDRKRIKGVIINKFRGDVALLQSGIDMIEELTQVPVIGVVPYAQLDIDSEDSVALVQKSRRFDSRKSLDIAVVSLKRLSNFTDFHSLEIQPDVSVRYVQPGDAIGRPDLLILPGSKNTIEDMNYLCESGLEAEILECLEQGVRIFGICGGYQLLGQKISDPLHLESDLEETRGLGILETETVLQPVKRTTQVRALHEGQELEGYEIHMGETQLADRLEPFSIIKEQNGEATERPDGAVAYGGQVQGTYLHGVFDNLEWTRQYLNELRLAKGLEPLEDQLVSIKDFKDREYDKLADVLRQSLDMEQIYQIINREEK
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: IDH3A_MACFA
Sequence: QKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGGSKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
What is the function of this protein?
Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate.  The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitric dehydrogenase subunit alpha, NAD(+)-specific ICDH subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y657_METMP
Sequence: MENVVITVVGVDKPGIVAEVTKVLAQNSANIVDIRQTIMEDLFTMIMLVDISKISSDFSELNVALEKLGSEIGVKINVQHENIFKYMHRI
What are the official names of this protein?
UPF0237 protein MMP0657.
What is the protein family that this protein belongs to?
Belongs to the UPF0237 family.
Protein: NDC1_HUMAN
Sequence: MATAVSRPCAGRSRDILWRVLGWRIVASIVWSVLFLPICTTVFIIFSRIDLFHPIQWLSDSFSDLYSSYVIFYFLLLSVVIIIISIFNVEFYAVVPSIPCSRLALIGKIIHPQQLMHSFIHAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSYSLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKAWISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHVFPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPHNWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQMPRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRRGPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIMYFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASAEHQKRLQQFLEFKE
What is the function of this protein?
Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope.  Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
What are the official names of this protein?
Nucleoporin NDC1, hNDC1, Transmembrane protein 48.
What is the protein family that this protein belongs to?
Belongs to the NDC1 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Multi-pass membrane protein. Note=Central core structure of the nuclear pore complex.
Protein: DER_LEGPL
Sequence: MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGIGVDDIEVDTLMSKQSQVALNEANVILFLVDGRSGLTGIDQQIAQALRKLNKKVHLVVNKTDGINEDIACADFQSLGITDIHAISASHGGGISSLLEEILEPFITEMHEATDDKAIKIAFAGRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDEKIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEEEHKEKIKSELSRRLHFANFAKIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLLQDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLDALPESYKRYLNNEFIKHLGLVGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKNKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: COAX_HALH5
Sequence: MILVIDVGNTNTVLGVYQDETLVHHWRLATSRQKTEDEYAMTVRSLFDHAGLQFQDIDGIVISSVVPPMMFSLEQMCKKYFHVTPMIIGPGIKTGLNIKYDNPKEVGADRIVNAVAAIELYGYPAIVVDFGTATTYCLINEKKQYAGGVIAPGIMISTEALYHRASKLPRIEIAKPKQVVGTNTIDSMQSGIFYGYVSQVDGVVKRMKAQAESEPKVIATGGLAKLIGTESETIDVIDSFLTLKGLQLIYKKNV
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
Protein: RECR_LISMO
Sequence: MHYPEPITKLIDSFMKLPGIGPKSAARLAFYVLDMKEDDVLDFAKALVDAKRNLSFCSVCGHITDKDPCYICADTSRDRSVICVVQESKDVIAMEKMRDFHGLYHVLHGTISPMDGIGPEDINIPDLLKRLQDDTIEEVILATNPNVEGEATAMYISRLLKPSGIKVTRIAHGLPVGGDLEYADEVTLSKAMEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RPO12_METJA
Sequence: MVEYKCLNCKKIIKLEELGKRARCPHCSYKILVKLRPKVVKHVKAR
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo12, DNA-directed RNA polymerase subunit P, mjP.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_PSEPW
Sequence: MSVELWQQCVELLRDELPAQQFNTWIRPLQVEAEGDELRVYAPNRFVLDWVNEKYLGRLLELLGENGSGIAPALSLLIGSRRSSAPRAAPNAPVSAAMAASLAQTHAQPAAAPVMAVADPVSVPTAEPAQASDMAEASSRDSYDSMADSAPAPVAPGRTEQRNVQVEGALKHTSYLNRTFTFETFVEGKSNQLARAAAWQVADNPKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSERFVADMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGWGLTVAVEPPELETRVAILMKKADQAKVELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRDITIELIRESLKDLLALQDKLVSVDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGDMFGGRDHTTVLHACRKINELKESDADIREDYKNLLRTLTT
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_BART1
Sequence: MSDEKNKFTDASFENCDLKNPADRNTLKQAADEFLKTHKTEAREDVEEESKEVDPLASLQDENKELKNQLLRLAADMENLRRRTARDVADARAYSIANFARDMLSVSDNLNRALEAIPEGARESDAGLKSLAEGVEMTERAMMAALERHGVQKIHPEGQKFDPHFHQAMFEIPNADVPDNTVQQVVQAGYIIGERVLRPAIVGVAKGGTKEASIETDKASHQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSV2_YARLI
Sequence: MRTPDAHVIASMEDQPILNAAFNQDSACFAICHNRGFRVYVTDPMDLRVQREFDDGGIGVIQMLHRTNYLAVVGGGSNPKFPQNKLVIWDDLKSKPALSLEFLSPVLNVLLSRTKIVVVLQNKVHVYAFSSPPSRISTTDTADNPHGIAAFSGDTVVFPSRTPGQIQVVDLSQEGQARNLVSIIRAHKSPVRCVTLSADGSVVASCSDNGTLVRLHSTSNTALLHEFRRGLDRAVVYNMAFSPSGSRLAVLSDKNTMHVFDTSASASGAAGAANRRHVLGKVPLLPSYFSGEWSFVSARVQGQHGVLGWSSETSVVVVWISEARWEKYVIVEKKPVEGSGKDQPGCELVREAWRAFKDL
What is the function of this protein?
Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways.
What are the official names of this protein?
SVP1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Vesicular and vacuolar.
Protein: SSRP_CHLAA
Sequence: MTATKHKHPGVVAENRKARHDYDIEETIEAGIVLSGSEIKSVRAGRVNLRGSFARVIDDEVFLYDAHIAPYEQSGKYFNHDPMRPRKLLLHRREINRLNGLVRMKGMTLVPLKVYFKGRRAKVELGVARGKKIYDKREDIARRDAARDIDRALKRARHDL
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: CYC32_DESVU
Sequence: GNAPAADMVLKAPGDAKMTKTAVP
What is the function of this protein?
Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin.
What are the official names of this protein?
Cytochrome c3-2.
What are the subcellular locations of this protein?
Periplasm.
Protein: CWP14_SOLLC
Sequence: ANPEVRNNLP
What are the official names of this protein?
23 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: GUF1_YEAS8
Sequence: MLKFRIRPVRHIRCYKRHAYFLRYNHTTTPAQKLQAQIEQIPLENYRNFSIVAHVDHGKSTLSDRLLEITHVIDPNARNKQVLDKLEVERERGITIKAQTCSMFYKDKRTGKNYLLHLIDTPGHVDFRGEVSRSYASCGGAILLVDASQGIQAQTVANFYLAFSLGLKLIPVINKIDLNFTDVKQVKDQIVNNFELPEEDIIGVSAKTGLNVEELLLPAIIDRIPPPTGRPDKPFRALLVDSWYDAYLGAVLLVNIVDGFVRKNDKVICAQTKEKYEVKDIGIMYPDRTSTGTLKTGQVGYLVLGMKDSKEAKIGDTIMHLSKVNETEVLPGFEEQKPMVFVGAFPADGIEFKAMDDDMSRLVLNDRSVTLERETSNALGQGWRLGFLGSLHASVFRERLEKEYGSKLIITQPTVPYLVEFTDGKKKLITNPDEFPDGATKRVNVAAFHEPFIEAVMTLPQEYLGSVIRLCDSNRGEQIDITYLNTNGQVMLKYYLPLSHLVDDFFGKLKSVSRGFASLDYEDAGYRISDVVKLQLLVNGNAIDALSRVLHKSEVERVGREWVKKFKEYVKSQLYEVVIQARANNKIIARETIKARRKDVLQKLHASDVSRRKKLLAKQKEGKKHMKTVGNIQINQEAYQAFLRR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: HMP_DICD3
Sequence: MLDQQTIATIKSTIPLLAETGPALTAHFYQRMFHHNPELKDIFNMSNQRNGDQREALFNAICAYATHIENLPALLPAVERIAQKHASFNIQPEQYQIVGTHLLATLEEMFQPGQAVLDAWGKAYGVLANVFIQRESDIYQQSAGQNGGWHGIRPFRIVAKQPQSSLITSFTLEPVDGGPIAAFRPGQYLAVYIRDKRFEYQEIRQYSLTNEPNGRYYRIAVKRETMGSVSGYLHDVAREGDVIELAAPHGDFYLEVTPETPVALISAGVGQTPMLSMLHSLKNQQHQADIFWLHAAENTEVHAFADEIADVAATLPQLQSYVWYREASSEAARSAHAFHGLMALKDLPTPLPMTNLHCYLCGPVAFMQFAARQLLELGITESQIHYECFGPHKVI
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress (By similarity).
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Hemoprotein X, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm.