PharMolix/UniProtQA huggingface dataset:
Protein: NRAM_I78A7
Sequence: MNPNQKIITIGSVSLTIATICFLMQIAILVTTVTLHFKQYECDSPANNQVMPCEPIIIERNITEIVYLTNTTIEKEICPKLVEYRNWSKPQCKITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTIHDRTPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCVTGYDKNATASFIYDGRLVDSIGSWSKNILRTQESECVCINGTCTVVMTDGSASERADTKILFIEEGKIVHISPLSGSAQHVEECSCYPRYPGVRCVCRDNWKGSNRPVVDINVKDYSIASSYVCSGLVGDTPRKNDRYSSSYCRNPNNEKGNHGVKGWAFDDGNDVWMGRTISDESRSGYETFKVIGGWSTPNSKLQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGREQETRVWWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: DAPD_SHEDO
Sequence: MEALRQRIETAFENRQHITPGTVEPSLRADVETVIAMLDKGEARVAEKINGQWQVHQWLKKAVLLSFRIFDNGVIDGGDTKYFDKVPQKFADYDEARFKAEAIRVVPPATVRKGSFIGKNTVLMPSYVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEIVEGVVVEEGSVISMGVYIGQSTRIFDRETGEVHYGRVPAGSVVVSGNLPSACGKYSLYAAIIVKKVDAKTRAKVGINELLRIVD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6E_AERPE
Sequence: MSEERPPLRIVISDPRAGDRVVRVKVKGVEDIEYTDDMRKTKESDRRRLPIARVSRKLYEELNLGEVGVLTLRFTTPDGKKVKVPFKAEVKEGLEDNVVEVNMELLGEAAGELETEADAFRAKSWQIAVPDDVHVKLAGLEIGDVFDGGLIGMPGLKFKIRGGTDATGIPMHPGVPGSGRYKVLLAGPPGFHPRERGERRRKSVRGRMIPDPRGERRKTALAQLNIVIHYGDKEE
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: SYQ_YEAST
Sequence: MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLASFVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITEDQVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGPKDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNEGFLGDLHKVGENPQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGKIIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPEGFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMRVGYFTLDKESTTSKVILNRIVSLKDATSK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: RNC_BRUSI
Sequence: MNRTRPLPEIKMVSANKTASILEERTGHRFLNLKRLERALTHSSVQAPARANYERLEFLGDRVLGLTVAEMLFEAFPEASEGELSVRLNALVNAETCAAIADEIGLADLIHTGSDIKSLNDKRLLNVRADVVEALIATIYLDGGLEAARSFIQRYWKKRSLETGAARRDAKTELQEWAHQQGNVHPVYAILSRSGPDHDPLFLVEVTVKGFAPEKGEGRSKRIAEQSAAEAMLYREGVWKRDGSA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDRC_STAAS
Sequence: MNNKKTVTNRKGMIPNRLNKFSIRKYSVGTASILVGTTLIFGLSGHEAKAAEHTNGELNQSKNETTAPSENKTTEKVDSRQLKDNTQTATADQPKVTMSDSATVKETSSNMQSPQNATASQSTTQTSNVTTNDKSSTTYSNETDKSNLTQAKDVSATPKTTTIKPRTLNRMAVNTVAAPQQGTNVNDKVHFSNIDIAIDKGHLNKDTGKTEFWATSSDVLKLKANYTIDDSVKEGDTFTFKYGQYFRPGSVRLPSQTQNLYNAQGNIIAKGIYDSTTNTTTYTFTNYVDQYTNVSGSFEQVAFAKRENATTDKTAYKMEVSLGNDTYSEEIIVDYGNKKAQPLISSTNYINNEDLSRNMTAYVNQPKNTYTKQTFVTNLTGYKFNPNAKNFKIYEVTDQNQFVDSFTPDTSKLKDVTNQFNITYSNDNKTATVDLMNGQTSSNKQYIIQQVAYPDNTSTDNGKIDYTLDTDKTKYSWSNSYSNVNGSSTANGDQKKYNLGDYVWEDTNKDGKQDANEKGIKGVYVILKDSNGKELDRTTTDENGKYQFTGLSNGTYSVEFSTPAGYTPTTANAGTDDAVDSDGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQDSTEKGIKGVKVTLQNEKGEVIGTTETDENGKYRFDNLDSGKYKVIFEKPAGLTQTGTNTTEDDKDADGGEVDVTITDHDDFTLDNGYYEEETSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDTDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDADSDTDSDSDAGKHTPAKPMSTVKDQHKTAKALPETGSENNNSNNGTLFGGLFAALGSLLLFGRRKKQNK
What is the function of this protein?
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis.  Mediates interactions with components of the extracellular matrix such as host NRXN1 to promote bacterial adhesion.
What are the official names of this protein?
Serine-aspartate repeat-containing protein C.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: RUVB_LEPIN
Sequence: MAKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPPGLGKTTLAGIISNELGTRLTITSAPVITKGADLARLLTSMGENEILFIDEIHTLPKKLEEILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRSGLISEPLKSRFGIQLRLDYYNDEEMKQIVLRSSKILGVLIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKKNLCLKAFEKMGIDDLGLDGMDRQILDCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESFMVRIGLINRTPAGRVATEKAYRQLKRMEDFSVHHGQDPTLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CCA_PYRIL
Sequence: MSTLEEVLREAYKLVTPSEEEERELKKVTEKVKALIADAINKYGIEAEIGVYGSSARSTWLPGQRDIDIFIVLTNRNINIKDVITLLSRYFSERGVTWSMRYAQHPYLSLLVDGYEVDVVPCYKISFGERPITAADRTPLHHKFLVEKLSEEQRRDVRLLKLFMKTIGVYGAEIKVEGFSGYLTELLVAYYGSFIDVLKAASRWRPYRTYITFSESRAKFKAPLVVVDPVDPERNVAAAVSLTSMSTFILASRRFLKNPSITYFQQRQGAVIKTNVVEVVFPYPNEPPDIVWGRYKRIGRSVFNWLKQCGFRVYRWGVESDEKSYVSLIYVVEQIELPPYMLHRGPPVYDGAVDAFVEKYLDKDIIGPFVQGSRVYVIKRRRYTNISDCLKTYLGKGDYTIRINLYEGALVRKNAWIT
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
Protein: EXP20_ORYSJ
Sequence: MGNILLQLLAVVALCIAPARSDWLPGTATFYGGADGSGTMGGACGYGNLYDQRYGINNAALSTPLFNDGASCGQCYLIICDYGKAPDWCKLGKAITVTGTNYGGWCNATRPYFDMSQPAWENIGIYSAGIVPILYQQVKCWRYGGVRFIINGFNYFELVLVTNMAGSGSIVSMSVKGSCTGWIQMTRNWGANWQCLAGLAGQALSFNVTSTGGQTIVFDDAVPAGWSFGQTFSTYHQFDY
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
What are the official names of this protein?
Expansin-A20, Alpha-expansin-20, OsEXP20, OsEXPA20, OsaEXPa1.1.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: ROBO2_MOUSE
Sequence: MNPLMFTLLLLFGFLCIQIDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKAMSTDEGTYVCIAENRVGKVEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGEPLPVISWLKEGFTFLGRDPRATIQDQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDMNDLPGPPSKPQVTDVSKNSVTLSWQPGTPGVLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVVVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQASTVWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPADHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGGRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPNYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTTYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSVQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKTKNSSKAQKNNGSTWANVPLPPPPVQPLPGTELGHYAAEQENGYDSDSWCPPLPVQTYLHQGMEDELEEDEDRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPAPPLGYVSGALISDLETDVPDEDADDEEEPLEIPRPLRALDQTPGSSMDNLDSSVTGKAFSSSQRQRPTSPFSTDSNTSAAQNQSQRPRPTKKHKGGRMDPQPVLPHRREGMPDDLPPPPDPPPGQGLRQQIGLSQHSGNVENSTERKGSSLERQQAANLEDTKSSLDCPAKTVLEWQRQTQDWINSTERQEETRKAPHKQGVGSEESLVPYSKPSFPSPGGHSSSGTSSSKGSTGPRKADVLRGSHQRNANDLLDIGYVGSNSQGQFTE
What is the function of this protein?
Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development.
What are the official names of this protein?
Roundabout homolog 2.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. ROBO family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: BFR2_USTMA
Sequence: MPPKTSSLASLLGTLTNAAPVDFDPEAPDADQPTFTTFANGSDDAASESGSDGDEDEDGDDDDDKEEEEELMNPRAHYADVATSDMRKRAALSESDKINDPRYHGVKSSRAELYADDYNGEHASDDDQDDQDDQEDEYGSDGDQDEDADQDDEDMEVASSKKDKKLRFAADNDESDDDSDSSQVNQTSAQASTSNSIAAQIAQSASQAKALKARRLEDAEKGRQVRKQIKTYERTLETRIKAQSVLRDINRLPDPQVYQQAMTSSSTCIEPAIVLLEQLLELSDTLFSLRTRLNTLSNSEEEEDGMVTAPSTRKRKRDFDVTVPEHQEEVEQTWTQIASHDQIDAVLNDVVGYSCALEPHRRRVLDKWSLKVTSAAAAAAAASNGNRFTQLRAVNQAPSSQIDSALAGDGLSRLVARTRVLRSESEGSFKLGSTSTSLDTEEKQDSEVFDDTDFYSTLLKELIERRSNGLSNQGGGTTSTAVLLSSLQGGGKKKKHNVDTKASKGRKLRYEVNDKLVNFMPPIRDRIKWGPEQIERLFRQLASSSMGVVKHVEAQDMQSDDEGQGDDMAKDAQLAGLRVFG
What are the official names of this protein?
Protein BFR2.
What is the protein family that this protein belongs to?
Belongs to the AATF family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MTA1_SORMK
Sequence: MSSVDQIVKTFAKLPEGERNAAVNAILAMMPPGPGPVRQIPEPVSQAPAPKKKVNGFMGFRSYYSPLFSQFPQKARSPFMTILWQHDPFHNEWDFMCSVYSSIRNYLEQSNAQREKKITLQYWLHFAVPVMGVLGRENYLPTLGWDLVTMPNGTIDLMRIAMPLFRKNLQPMNGLCLFTKCQEGGLQVDNQHLVIAKLSDPSYDMIWFNKRPHYQQRHAVQADSSELGVSALFPRNHAVAAEADDVATLQLPHWMQQGDFGTESGYSPQFETLLGSILENGNATSNDSYNMALAMDVPMMGFNGGA
What is the function of this protein?
Required for mating.
What are the official names of this protein?
Mating type protein SmtA-1.
What is the protein family that this protein belongs to?
Belongs to the MATALPHA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAX_BURO1
Sequence: MSEPHLLIDAGNSRIKWALADARRSLVDTGAFGHTRDGGADPDWSHLPRPRGAWISNVAGADVAARLDALLDARWPGLPRTTIRARPVQCGVTNGYTTPEQLGSDRWAGLIGAHAAFPGEHLLIATFGTATTLEALRADGRFTGGLIAPGWALMMRALGTHTAQLPTLTTDIASGLLAGAQAEPFQIDTPRSLSAGCLYAQAGLIERAWRDLVAAWQAPVRLVLAGGAADDVARALTVAHTRHDALILSGLALIAADAAPATAQD
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
Protein: Y3782_KORVE
Sequence: MPLRKTKKKKVLPKSPRAPKLQPSELVIITGLSGSGKASVLKAFEDLGYYCVDNLPVDLVPQFADLVADSPEINRAALVLDIREGQGLDRLPATLRSVRQIVKSNVVFLEADDEILLRRFSETRRPHPLGISMPVKASIESERRRLAPIRKVADMMIDTSKFNVHELRALIFDRFGHARTQDHKKILVSCVSFGFRKGVPDDADLLFDVRFLPNPHFVPEFRPFTGRHPKVAKYIRSFPQTQEFINRISELLVYLLPHYISEGKSYLTIAFGCTGGQHRSVMIAEDVKKRLATAGYNVKVVHRDSPK
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Acid345_3782.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CLPX_DELAS
Sequence: MAEKKGSSSEKNLYCTFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEQPSTEAKDGRGDLPTPAEIKANLDNYVIGQDLPKRTLAVAVYNHYKRLRHKDKAGKDEIELAKSNILLIGPTGSGKTLLAQTLARMLNVPFVMADATTLTEAGYVGEDVENIIQKLLQSCEYDVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQIDTTNILFICGGAFAGLEKVIENRTEASGIGFGATVKSKKQRSISEVFQEIEPEDLIKFGIIPELVGRMPVVTALAELGEDALVQILTEPKNALVKQYSKLLAMEGVELEIRPAALKAIARKALARKTGARGLRSILEQSLIGTMYELPNADNVEKVVVDESTIEDGKAPLLVYREAAKKA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RL16_UREP2
Sequence: MLQPKRTKFRKPHKVSYEGKAKGNKQVDFGEFGLMALEGAWIDARQIESARIAISKRLLKTGKMWIRIFPHMSLTKKPLEVRMGSGKGSPEKWVAVVKAGTVMFEIANVSEELMCEALRAAGNKLPIKVKIVKKGEAN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PYRB_LISMO
Sequence: MKNLLSMEALTVHEIEHLLEQAAQFKRGKKATFNEQTFAVNMFFEPSTRTHTSFEVAEKKLGVEVVSFDAASSSMTKGETLYDTLLTMQAVGVNVAVIRHSEENYYAGLEKLDIAIVNGGDGCGEHPSQSLLDLFTIKEQFGTFQGLKVAIAGDIRHSRVANSNMKVLKRLGAELFFSGPREWFDESYLAYGTYLPVDEIVEKVDVMMLLRVQHERHSGTDEFTKESYHEKFGLTEDRAKKLKEDAIIMHPSPVNRDVEIADSLVESEKSRIVTQMTNGVFIRMAILEAILKEQEMRAKLCTY
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MOAC_ECOHS
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGSVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: SAS2_YEAST
Sequence: MARSLSQSLTATTQKLKGKKNGGKGKNKPSAKIKKTQKEMLYGILNERNIRQIQFGLNKKFSTWYGSAVYFDPETKRLGCSETKGQLSSVSNSQYWLDTLFVCEYCFKYTDDQTRFVGHVASCPFQYRVPGKIKYKSPEYTIRRVKGSKYQLFCQCLCLFTKLYLDNKSMYFKVDHYEFYIVYETGSTKPMGFFSKDLVSYQQNNLACILIFPPYQRRGLGLLLIEFSYKLSQLEGVISGPEVPLSPFGLIGYLKYWSQILCWHLIEGDLAHYDKVTLEDLSIVTGMRVNDVILTLKHLNCIGENNQIYLQSLNSWLKLHGTKRNWFKLKDEYLLIDD
What is the function of this protein?
Histone acetyltransferase (HAT) subunit of the SAS complex, a multiprotein complex that acetylates 'Lys-16' of histone H4 and 'Lys-14' of histone H3.  The SAS complex is however unable to acetylate nucleosomal histones.  The complex is involved in transcriptional silencing at telomeres and at HML locus.  Also involved in rDNA silencing and G0 control.
What are the official names of this protein?
Histone acetyltransferase SAS2, Something about silencing protein 2.
What is the protein family that this protein belongs to?
Belongs to the MYST (SAS/MOZ) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HSD3B_CAEEL
Sequence: MSIKRLSMRLKKGIHRSWNRMTSLEAGLEEEKEIKIVEEPEPRPWKVLITGGAGHLAENLVAKLEEMTRDSIRPKIREMLEKEMPAVISTKVDKEVEKRLPMYIQIVLVDVLEPRGRVLKHHVAFVKCSFDDECTMKTALEQVDTVYHLAAVGMTGQYARDRKACMDINAVGTMNLLIWARNSGVQRFIYTSSVGVVFSGEPMYNATEEVGYPDDFYNYYCESKAHAERIVQKASGHRMRTTVLRFNGIYGPGEKRVTERVVKFMLTGMWIATCKPNGVEAQTQLSSVANCIQGLVKAELALRWSDTPHGQIYNIMDKTPVGTFSFWTPLNIALGFSSSMITVPATPIRLFAYLSQIIADRMRIDPIVSVLEVDLLLVNNTFNIEKAERDLGYEPSVSAIPEIIEHYLHRLPPDVVRPKGRSDFYVKVAVLVLGTILIFVAVFSFTFWMYLIFQRLSRWNPF
What is the function of this protein?
Hydroxysteroid dehydrogenase involved in the biosynthesis of dafrachonic acids (PubMed:18495818, PubMed:20178781, PubMed:24411940).  Catalyzes the dehydrogenation of cholesterol or its derivatives and the isomerization of the double carbon bond on the sterol ring.  Modifies sterols into a Delta(4)-3-keto-sterols such as cholest-4-en-3-one, precursor of Delta(4)-dafachronic acid (PubMed:18495818).  Contributes to the production of Delta(7)-dafachronic acid in the XXX cells (PubMed:24411940).  Dafachronic acids act as ligands and bind directly to the nuclear hormone receptor (NHR) daf-12 suppressing dauer formation and inducing reproductive growth (PubMed:18495818, PubMed:24411940).  Acts in parallel to AKT-1 to promote reproductive development via DAF-16/FoxO and DAF-12 (PubMed:20178781).
What are the official names of this protein?
3beta-hydroxysteroid dehydrogenase/Delta(5)-Delta(4) isomerase 1, HSD-1, 3beta_HSD domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MED5_ASHGO
Sequence: MVRAQETVYDLITKCSVRRVPPKQFVNFYNEFFNERYDSVLENGNPAGESRPTAPVYEEVAQDLVRILNDSRVNLVADYVLEIVLINLNVDLLRLFLPKLHHVRNVMLLVHLFSRATAFISGLDNKLLAEQISDTVYTDVTPAVLSFNMQAIDDQLVIVLAKFLHAVLRLPEGQQKMGSVPTKQKAATLLQRLSTIDRLLYKRFIADLDGKLRLSGAPADMSFPLPPSNMPSPSVTSPKYETSSVGVMKRSTSMSNEAKYQDIKLARYYKNLWLNNKIHYCTVSDPLFLEKYDSILELATGGGLSADRPVKAKIADLVETAFTCFAQFVSNKLYHQSNSNFSLLERKWTVFVTKQLPLIIKSSIPDKTDIVLRTLENIDDKVIKAIKSYNTEKEEVKNRTEDLFDDYPVNSLDIRHEFLKNLIMMGLQPPTVLNEYLREDQMVDLKSLVTSEHLIIDNSQGVRETILNVRNFITKSIESLEFENLFDDGNQLLVTNDHGIIQIAHNLETISPTKQLEIANILYDLLSAAIESLDHKTISKVLTILTLNVGHLLTNIFCLTGYEKFARAVIRFIDVIWESNKSKSNDMVSDDSEFENINSAMAYTLSLCFIIHVVDIYGVNVEALVENPSKSTVLRFLSKLGEIPEVFVAPEGDLESSKTLLQQWLRELFVKNLISDNLMKSADVKVMGFMIPFIFKQTLLNVEYGIISDISSFVNGFEYFLQPFLSVGLINIVFWLEKYLLALKTTESFPKINGALFDILGAIIAPKSIGSDAKAIHSVVLKLKCVGLLKELKSFQVPSESNYGIYSSQTRQDPRLEALISKLELIAQSSALYDVDPRIISAVNNNYSQKHISYNKVVLTSDIPINKIMTNQINSFWNLHSSTYYNFDYLLELIDLVTPFKFVQDVFQTLKYKVTAYGVPGSATKPSSAALDQVLGYVFYFMVLRDIKCPEEKSLLLEYLDSGRFPSSISATVLTSDPTTISGMPPVSMPYDVKSEQDAMEGVDEDFDMLFGESFSGLPDDVQKSADMKPDTGIKEDDSEKSSYVSAARLTESFGVIFSKMKKDKLEAYQAGQISEERYQCFMGLYDKYVQTLRHSVI
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 5, Mediator complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CTAA_FLAPJ
Sequence: MKNNKSVIIWLLSGCFLVFIMVVVGGITRLTNSGLSMTDWHLVTDTFPPLTEAKWEETFEKYKLFPEYQKINIHNDFTLSDYKFIYFWEWFHRFIGRIIGLVFIIPFIYFLIKKKLNTETLRKCAILLGMGAFQGFLGWFMVKSGLIDAPDVSHFRLSLHLTFAFITFAYTLWVALDLIYPEKKQVILPLRNIARITLAIIILQIIYGGFVAGLNAGLIHNHWPLMSDGQFFHESIILEKESWFARFTEGKSGVQFVHRTIAYFVAGLIVFLTFKSKKHTLSLEQKNGLNALLIIVFIQFTLGVLTLLYSVPLWLGVIHQAMAFILLATTTYTLHRFSK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.