PharMolix/UniProtQA huggingface dataset:
Protein: TF7L2_MOUSE
Sequence: MPQLNGGGGDDLGANDELISFKDEGEQEEKNSENSSAERDLADVKSSLVNESETNQDSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQTLKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCSL
What is the function of this protein?
Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner.  Acts as repressor in the absence of CTNNB1, and as activator in its presence.  Activates transcription from promoters with several copies of the Tcf motif CCTTTGATC in the presence of CTNNB1.  TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1.  Expression of dominant-negative mutants results in cell-cycle arrest in G1 (By similarity).  Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
What are the official names of this protein?
Transcription factor 7-like 2, HMG box transcription factor 4, T-cell-specific transcription factor 4, T-cell factor 4, TCF-4, mTCF-4.
What is the protein family that this protein belongs to?
Belongs to the TCF/LEF family.
What are the subcellular locations of this protein?
Nucleus, PML body. Note=Diffuse pattern. Colocalizes with SUMO1 and PIAS4 in a subset of PML (promyelocytic leukemia) nuclear bodies (By similarity).
Protein: MDTI_SHIF8
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATK_ACTCH
Sequence: MKEFKRYLELDRSQQHDFVYPLLFQEYIYVLAHDHGLNRSILLENADYDNKFSLLIVKRLITQMDQQNHLIFSPNDSNQNPFLGHNTNLYSQMILEGFAVVVEIPFSLRLISSLEGKETVKSHKLRSIHSIFPFLEDKFSRLNYVLDILIPHSIHLEILVQTLRYWVKDASSLHLLRFFLHEYRNWNTRITPKKSSFSFSKRNQRFFLFLYNFHVCESESIFVFLRNQSSHLRSISSGTFLERIYFYGKIEHFVKVFTKDFQDILWLFKDPFMHYVRYQGNSILASKGTSLLMNKWKYYLVNFWQCYFYMWCQPGRIQINQLSNHSLDFLGYLSSVRLNPSMVRSQMLENSFLIGNAIKKFDTIVPIIPLIGSLYKAKFCNVLGHPVSKPVWADLSDSDIIDRFGRIYRNLSHYHSGSLKKTSLYRIKYILRLSCARTLARKHKSTVRAFLKRLGSELLEEFFTEEEQVFYLTFQKTYSTSQGLSRGRIWYLDIICINDLANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TIM10_CRYNB
Sequence: MSFLFGGNNRSVEGSVDPAKIEMAVAELDMITDVFNRLVNSCHTKCISSTPLNHRYAEGDLLKGESVCIDRCTAKFFEVNKKVGERMSAMGSAAQATGSFGR
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM10.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: SEC14_YARLI
Sequence: MTVTEQEFLASYPQKVAPGGPTGYPGNLTAEQEQKLGELKMILLTKGYEDRTDDATLLRFLRARKFDVPLAQEMWENCEKWRKEFGTNTILEDFWYKEKKEVAKLYPQYYHKTDKDGRPVYVENVGKVNIHEMYKITTQERMLRNLVWEYESFVRHRLPACSRVVGHLIETSCTILDLKGVSLSSASQVYGFLKDASNIGQNYYPERMGKFYLINAPFGFSTVFSVIKRFLDPVTVSKIHVYGSNYKEKLLAQVPAYNLPIKFGGQSSSKIGVELSDDGPWRDPQFVGPEGLAPVAGERPTGAPSIVSNSSTYAKSTASTKVGADDKATDAKANGNGAAAAAAGAGTAAAGGAAAAAGASSSKQAAPAQAAPAQAAKAPVPAAAKTATAPAPTGKTAAPQTNSFPPEMLAMMEQNEKKAEKAAEAKTKGGAAPQANAFTDEQLAQLNSLPQQVATGGVSQPLPDSHVTQGVPTVAKIAEAAAGPHEDAHLPH
What is the function of this protein?
Required for transport of secretory proteins from the Golgi complex.  Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro.
What are the official names of this protein?
SEC14 cytosolic factor, Phosphatidylinositol/phosphatidylcholine transfer protein, PI/PC TP.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: SIHH_METJA
Sequence: MYEVRDINLWKEGERKIQWAKQHMPVLNLIRERFKEEKPFKGITIGMALHLEAKTAVLAETLMEGGAEIAITGCNPLSTQDDVAAACAKKGMHVYAWRGETVEEYYENLNKVLDHKPDIVIDDGCDLIFLLHTKRTELLDNIMGGCEETTTGIIRLKAMEKEGALKFPVMDVNDAYTKHLFDNRYGTGQSALDGILRATNLLIAGKTVVVAGYGWCGRGVAMRAKGLGAEVVVTEVNPIRALEARMDGFRVMKMEKAAEIGDIFITTTGCKDVIRKEHILKMRNGAILANAGHFDNEINKKHLEELAKSIKEVRNCVTEYDLGNKKIYLLGEGRLVNLACADGHPCEVMDMSFANQALAAEYILKNHEKLEPRVYNIPYEQDLMIASLKLKAMGIEIDELTKEQKKYLEDWREGT
What is the function of this protein?
Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine.  Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions.  Can also catalyze the reverse reaction in vitro, i. e.  the synthesis of SIH from Hcy and inosine.  Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy.
What are the official names of this protein?
S-inosyl-L-homocysteine hydrolase, SIHH.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBHG_SALNS
Sequence: MKKPVVIGLAIAAIVAVIAGGTWWYQSRQDDGLTLYGNVDIRTVNISFRVGGRLASLNVDEGDAIKAGQVLGELDHAPYENALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVRQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLSQYRTGNREQDIAQAKASLEQAKAQLAQAQLDLQDTTLIAPANGTLLTRAVEPGSMLNAGSTVLTLSLTRPVWVRAYVDERNLSQTQPGRDILLYTDGRPDKPYHGKIGFVSPTAEFTPKTVETPDLRTDLVYRLRIIVTDADDALRQGMPVTVKFNDEARHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRPA_ACIB5
Sequence: MSRLATRFEKLQSQQRKALVSYVMAGDPQPQVTVPLLHKMVAAGVDVIELGLPFSDPMADGPVIALAAERALAAGTNTLDALNMVKEFREQDQETPVVLMGYLNPVEVIGYEKFVSYAKQCGVDGLLLVDLPPEESKEFGAILKQHDMDQIFLLAPTSTDQRIQHVANQASGFIYYVSLKGVTGAATLDTSEAAARIEKIKGMTNVPVGVGFGISDAASAKAMGSVADAVIVGSAFVKSFATLAADEAVEQTVNKVKELRAALDELV
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CHEB3_PSE14
Sequence: MKIAIVNDMPMAIEALRRALAFEPAHQIIWVASNGADAVQRCVEQTPDLILMDLIMPVMDGVEATRRIMAETPCAIVIVTVDREQNMRRVFEAMGHGALDVVDTPAIGGPNPKEAAAPLLRKILNIDWLIGQRVGREHVVAAPRSEPARRDRLVAIGSSAGGPAALEILLKGLPVSFPAAIVLVQHVDQVFAAGMAEWLSSASGLPVRLAKEGETPQPGVVLLAGTNHHIRLLKDGTLAYTAEPVNEVYRPSINVFFESVTRYWSGEAVGVLLTGMGRDGAQGLKAMRERGFLTIAQDQASSAVYGMPKAAAAIDAAVEIRPLPAIAPRLVEVFTQ
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 3.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCAT2_PONAB
Sequence: MAAAALGQIWARKFLSVPWLLCGPRRYASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWSDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGTYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKQGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDLAQTWGEFRVVERTITTKQLLQALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV
What is the function of this protein?
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine (By similarity).  May also function as a transporter of branched chain alpha-keto acids (By similarity).
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase, mitochondrial, BCAT(m).
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NOVK_STRNV
Sequence: MTRVAVVAGGGEHTGPAVALRLAAGGFDVALLGSEFTSADKTVRRVEEYGRQCVTVRAELSDARSVAVAFGRVRTALSGPAVLVTCVGPQPLPDGLPEDESADEQRYTAVRRALRPVFVCCQAGAGQLLRHRWGRIIIVTEPADADGNTWRTSRPVLDGLIGFTRSAALELARSGTTVNLVAPADRAADSRAPAHRAAGDDSAGSYADGVAHVTEFLVDERAVGITGQAIRVAARADVPLLRER
What is the function of this protein?
Non-catalytic subunit of the NovJ(2)K(2) heterotetramer that catalyzes the NADPH-dependent reduction of the tyrosyl moiety of L-beta-OH-Tyr-S-NovH intermediate to yield the tethered beta-ketotyrosyl-S-NovH in the novobiocin biosynthesis pathway.  Novobiocin is an aminocoumarin family antibiotic that targets bacterial DNA gyrases.
What are the official names of this protein?
Short-chain dehydrogenase/reductase family member NovK, Novobiocin biosynthesis protein K.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: CUTC_PHOPR
Sequence: MTIQLEVCIDNLESLHYAQQGGASRIELCSSLALGGLTPSAGFMQLAAKHASIPVYAMIRPRQGDFLFSSDDVEIMLADIHAAKKAQLQGVVIGVLTQEGHIDRDILNSLMKEANGLGVTFHRAIDQCIDPMAALDNIMAAGCERILTSGLQANALDGVDMIAEMVTYCGDNLSIMAGAGVTATNAKQIITRTGIREIHLSGKSTRPSHMVQFANQAHMGSADIDDFSIPVTSVEKISAVINAIR
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_OCTVU
Sequence: GIWSGLLGTSLSLMIRTELGQPGSLLNDDQLYNVIVTAHAFVMIFFLVMPVMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPSLTLLLSSAAVESGAGTGWTVYPPLSSNLAHMGPSVDLAIFSLHLAGISSILGAINFITTIINMRWEGMLMERLPLFVWSVFITAILLLLSLPVLAGAITMLLTDRNFNTTFFDPSGGGDPILY
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1680_STAAC
Sequence: MADESKFDQFKGNVKETVGNVTDNKELEKEGQQDKVIGKAKEVVENAKNKITDAIDKLKK
What are the official names of this protein?
UPF0337 protein SACOL1680.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: EFG_SYNR3
Sequence: MPRDFPLDRVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERGITITAAAISTAWNDHRINIIDTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSVPRMVFVNKMDRTGADFLKVYGQIVDRLKAKAAPIQLPIGAEGDLSGIIDLVANKAYIYKNDLGTDIEEAEIPADMADEAAEWRAKLMESVAENDEELIEKFLETGELTEAELKKGIRDGVLKHGLVPMLCGSAFKNKGVQLVLDAVVDYLPAPIDVPPIQGVLADGSEAVRPSDDNAPFSALAFKVMADPYGKLTFVRMYSGVLSKGSYVMNSTKDVKERISRLVVLKADDREEVDQLRAGDLGAVLGLKNTTTGDTLCDPDNSIVLETLFIPEPVISVAVEPKTKGDMEKLSKALTSLSEEDPTFRVSTDEETGQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYRETIRSSSKGEGKFARQTGGKGQYGHVVIEMEPGEPGTGFEFINKIVGGAVPKEFIKPAEMGMKETCESGVIAGFPLIDVKCTMVDGSYHDVDSSEMAFKIAGSMAFKDGVKKCNPVLLEPMMKVEVEVPEDFLGSIIGDLSSRRGQVEGQSIDDGISKVSAKVPLAEMFGYATQLRSMTQGRGIFSMEFSRYEEVPRNVAEAIISKNQGNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_DESHD
Sequence: MAQHFDFEKPILELEQKIAELQEFSKEKDINLSPEISKLMRRLVRLRKEIYGNLEPWQKVQIARHMERPNFYDYAPLLFEDFMEFKGDRLFADDKAIVGGIAIFQGIPVTVVSHIKGRGTKENIQRNFGMPHPEGYRKALRLMDQAEKFHRPILTFIDTPGAACDLEAEERGQGEAIARCLQAMAGYSVPIICTVIGEGGSGGALALGVGNKVLLLENSFYSVIAPESCASILWKDPGKAKEAASALKFTAQDLLELGIADGIIKEPLGGAHRSVERTAEEMKKTIAEALAELRELPPDELRTMRYEKLMNYGEFEEKA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_WOLWR
Sequence: MESGKTTIAKIIKRNEPGGRVPIWLMRQAGRSLPEYRKAVENMNNFMEICYNTDLVTELTLQPVTRFDMDAAIIFSDILIIADVLGCDVNFVRGVGPIIKPVESPKELKGPQEIETKTLPILNAIKKVRSQLPKEKSLIGFAGGPWTVASYIIEGGSSKTFSKVLNFYPSCLKEIIERITEVTIIYLIKQIEFGADVIQLFDSNAGALSEPLFKEYVIEPTKRIILAIKDRFSDFPIIGFPRSAGNLYKDYCEQTGVSAVSIDYNVPIKWAKANLNIPLQGNLDPNLLAYNKTEAIKEAKRIIDCFRDLPFIFNLGHGVLPDTPVENIAALVNLVKSY
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAP1_SCHPO
Sequence: MASTQVVFIVTLFLYLLITRWRRKNEKSFIASEEPKQPEWRDYTPAELKEYNGSKNSLVFLAIKGTVYNVTMGSKFYGPQGPYSAFAGHDASRGLAKNSFDDEFIPDSDAEELDDCSDLNDEERQALNDWKAFFDQKYQAVGRLISPREARAAATISETEEKVAHN
What is the function of this protein?
Required for sterol biosynthesis.  Functions as a positive regulator of cytochrome P450 enzymes erg5 and erg11.  Function requires bound heme.
What are the official names of this protein?
Cytochrome P450 regulator dap1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family. MAPR subfamily.
Protein: CNR1_PELLE
Sequence: MKSVLDGLADTTFRTITTDLLYMGPNEVQYEDTKSDLSKLGYYPQKLPLSSYQEKIIDGQSTLHLDSFNATEFYNKSITTFKDGDGNIQCGNNFMDMECFMILTPSQQLVIAALSITLGTFTVLENMLVLCVIFQSRTLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRIDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLSYKRIVTRTKAVIAFCMMWTIAIVIAVLPLLGWNCKKLKSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHHHAVRMLQRGTQKSIIVHTSEDGKVHITRPDQTRMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKTVKTVFAFCCMLCLLNSTVNPIIYALRSKDLRSAFCSMFPNCEGTAQPLDNSMESDGQNRHAHNSNVHRAAESCIKSTVKIAKVTMSVSTDTSAEAV
What is the function of this protein?
G-protein coupled receptor for cannabinoids (By similarity).  Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues (By similarity).  Regulates cellular respiration and energy production in response to cannabinoids (By similarity).  Signaling typically involves reduction in cyclic AMP (By similarity).  May be involved in the control of reproductive function (PubMed:16485273).
What are the official names of this protein?
Cannabinoid receptor 1, CB-R, CB1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Mitochondrion outer membrane. Cell projection, axon. Presynapse. Note=Unexpectedly, in the mitochondria, the C-terminus is located in the mitochondrial intermembrane space, a compartment topologically considered as extracellular. In canonical seven-transmembrane G-protein coupled receptors, the C-terminus is cytosolic.
Protein: PXMP2_RAT
Sequence: MAPAASRLRVESELRSLPKRALAQYLLFLKFYPVVTKAVSSGILSALGNLLAQMIEKKQKKDSRSLEVSGLLRYLVYGLFVTGPLSHYLYLFMEYWVPPEVPWARVKRLLLDRLFFAPTFLLLFFFVMNLLEGKNISVFVAKMRSGFWPALQMNWRMWTPLQFININYVPLQFRVLFANMAALFWYAYLASLGK
What is the function of this protein?
Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the peroxisomal membrane.
What are the official names of this protein?
Peroxisomal membrane protein 2, 22 kDa peroxisomal membrane protein.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: ZN345_HUMAN
Sequence: MENLTKHSIECSSFRGDWECKNQFERKQGSQEGHFSEMIFTPEDMPTFSIQHQRIHTDEKLLECKECGKDFSFVSVLVRHQRIHTGEKPYECKECGKAFGSGANLAYHQRIHTGEKPFECKECGKAFGSGSNLTHHQRIHTGEKPYECKECGKAFSFGSGLIRHQIIHSGEKPYECKECGKSFSFESALIRHHRIHTGEKPYECIDCGKAFGSGSNLTQHRRIHTGEKPYECKACGMAFSSGSALTRHQRIHTGEKPYICNECGKAFSFGSALTRHQRIHTGEKPYVCKECGKAFNSGSDLTQHQRIHTGEKPYECKECEKAFRSGSKLIQHQRMHTGEKPYECKECGKTFSSGSDLTQHHRIHTGEKPYECKECGKAFGSGSKLIQHQLIHTGERPYECKECGKSFSSGSALNRHQRIHTGEKPYECKECGKAFYSGSSLTQHQRIHTGEKLYECKNCGKAYGRDSEFQQHKKSHNGKKLCELETIN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 345, Zinc finger protein HZF10.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: METN2_PSE14
Sequence: MTATAQRQLPLDTPSASTLAQQAELHPELNRAHVRFINLGKTYHGKQGPVEALGNIDLAVQRGEIFGIIGRSGAGKSSLIRTINRLEQPSSGRVLIDQVDIGEFDEDKLVELRRRIGMIFQHFNLMSAKTVWQNVELPLKVAGVPREQRARKVAQLLELVGLQDKHNAYPAQLSGGQKQRVGIARALVHDPAILLCDEATSALDPETTQSILGLLREINQRLGLTIVLITHEMAVIRDICHRVVVLEQGRIVEQGPVWQVFGDPQHDVSKTLLAPLQTGLPKEWAERLSDQPQRPDAALLLDVHFTGASDQGPDLAALFAALGGKVQLLQGGVERIQERAIGHLILSVAGSVHTRDELLARARQLAPRAEVLGYVG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EPAD1_ORYSJ
Sequence: MERSHLAVLLGLLAFAAGVPAAAAATAVEGAQAATAEASCEPSILATQVSLFCAPDMPTAQCCEPVVASVDLGGGVPCLCRVAAEPQLIISGLNATHLLTLYAACGGLRPGGARLAAACEGPAPPASIVTAPPPPVAFRRKPPAREAPPPPPAAEKLSPPPQQHDDSDHNKRVGPLPRGSPPPYAQSVPVGPAAAPPPPRSGASSSLQAPLAATTTIVAITLIAAAQY
What is the function of this protein?
Plant non-specific lipid-transfer protein that binds phospholipids in vitro (PubMed:33093144).  Required for correct pollen exine patterning by controlling the continuity and homogeneity of the primexine distribution (PubMed:33093144).
What are the official names of this protein?
Non-specific lipid-transfer protein EPAD1, Protein EXINE PATTERN DESIGNER 1.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=Localizes to the microspore plasma membrane.
Protein: YJFC_BACSU
Sequence: MNLVMEKTFEQYEKLFSMEEQKREDVFRYTMMRPFEKMWTAIQVPLKAKEPNGYDVIMAAKMLGYLDVRDAESGQKALQILKESHVSETAESALRQCIFFAEREQLRVNAKEIKFGLYIADPNKLQLQKGYCGFGGIPGFIHVWINPNSYNLPRIPSIIAHEFHHNVRFSYIDFHHGSVSVGDYLVIEGLAESFARELFGTERLGPWVTRFDHEDLQYSIDVINEVLDVKGFSEVSRYMFGDPIANDQGFKPAGLSAFAGYAVGYHAVQSFMNQHHITISEATRLDAKTIISQCGLFST
What are the official names of this protein?
Uncharacterized protein YjfC.
Protein: METN_GEOKA
Sequence: MITLEQVTKIYQAANGSVTAVDNVSLEIREGEIFGIIGYSGAGKSTLIRLLNGLEKPTSGRVVVAGRDMTRVKGRELRKARQEIGMIFQHFNLLWSRTVRENIAFPLEIAGVPKEERNKRVDELIELVGLSGREDAYPSQLSGGQKQRVGIARALANNPKVLLCDEATSALDPQTTDAILDLLVDINKRLGLTIVLITHEMHVIRKICDRVAVMESGRIVEQGEVLHVFRNPQQPITKRFVKQLIEPEETEEAISHLFGQYPSGLIAQLTFVGAAAGKPLITEVVRQFAVDVNILQGKISQTHQGAYGVLFVHLDGARDEIDRALDYIQRQQVAVEVIHDAR
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ASCL2_BOVIN
Sequence: MDSRALPRPAPPAPGVPGCCAARRRPESPELLRCSRRRRPGAVDPGSGAAAVARRNERERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSAVEYIRALQRLLAEHDAVRAALAGGLLAPAVRHPLPRAPSGTPATAASPSCASSSPGRGHSSEPGSPRSAYSSDDSGCEGALSPAERELLDFSSWLGGY
What is the function of this protein?
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
What are the official names of this protein?
Achaete-scute homolog 2, Mash2.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYYR1_MOUSE
Sequence: MDALRLPRRPGVLLPKLILLFVYAGDCLAQCGKECHSYCCDGSTPYCCSYYAYIGNILSGTAIAGIVFGIVFIMGVIAGIAICICMCMKNNRGTRVGVIRAAHINAISYPMAPPPYTYDHEMEYRTDLPPPYSAAPQASAQRSPPPPYPGNPRKYSSSQNRIRDN
What are the official names of this protein?
Cysteine and tyrosine-rich protein 1, Proline-rich domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the CYYR1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.