PharMolix/UniProtQA huggingface dataset:
Protein: DXS_ECO55
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPDAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLGAAGMEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: HIS6_TOLAT
Sequence: MLARRIIPCLDVKDGVVVKGIQFRNHEVMGDIVPLAKRYADEGADELVFYDITASSDARVVDKSWVSRVAEVIDIPFCVAGGIKSVEDAKRILEFGADKVSINSPALENPALITELADRFGVQCIVVGIDSYFDAATGQYQVKQYTGDENRTRITKWTTPDWVVEVQKRGAGEIVLNMMNQDGVRQGYDLTQLKLIRDLCKVPLIASGGAGEMVHFRDAFQIADVDGALAASVFHKGIIPIPELKAYLRNEGVQIRD
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWC27_CRYNB
Sequence: MSNLYATEPATNGKVIIDTTAGEIEVELWGKECPKAVRNFLALTMEGYYDGVIFHRVVPGFIIQSGDPTGTGMGGESFYGEPFEDEIHGRLKFNRRGLLGMANNGSRNSNTSQFFITLDAAPELTNKHTMFGKIVGNTIFNVLNIGNLDTDKEERPLIPPKIRRIHIIENPFDDIVPRITAEEKKAQQKAKLEAKKDMEQRERRAKAKKNTGLLSFGDSEEIPEEEVTVKKKSMTRQDLVDPSEAEHTKSKTSKMTETFVNIPPSLKDLGKSRENEASEEKKAVDLKNIRAQHEREKAGGSAARQAEIKRMEEDLRRLKKRSGSVSDSESDSSSRARRKGPSYLEQELAKYASKRGRAAMKAGNKRGRRDEEEDVLTEMRKFSKRVMQAGDEPEEEQAEEIEEGEAKEEGTGIGAAMAEEEGGIEVDDDVGWLTHKLKFQVDDKELTRRAEDEYAVIDPRAKARDLLGKPDKKKLKGNPNRRTVRNSGRNR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Involved in pre-mRNA splicing (By similarity).
What are the official names of this protein?
Peptidyl-prolyl isomerase CWC27, PPIase CWC27, Rotamase CWC27.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PEX12_EMENI
Sequence: MEYLPSLQQEFDELKPSLFELLAEQQLSDLLPPSIRYILAVATHRHPRYLLRVLNSFDEVYALLSLVVERYYLRNFGGSFTENFYSLKRERVLLTKNGEIPRAQLGAPGPVRESLKLRNSDVWKNLLVMVGIPYLKRKLDEGYDIHAAPQASLIMNGGPRYNPSDDLPPHPTIRQRFMHAYKWFLRNVYPSFNAAYYFSILAFNLAYLFDNTKYSSPFLWLIGTRIRRLSSADHQAIAKILEGKPQTPNSRSARSRPGSGLLGLFSPHNLYPQLLTSLRYFLPASIFALKFLEWWHASDFSRQLARKATDTLDIPAPITKGMISPSERKSRPPTKQKEDPESPKSALKTSSPHKRIQPPISASSYLPIFTVPLPPADSDAASSCPVCLNQLTNPTACQTGYVYCYVCIFHWLNGEHQRQIDFMNGDGAGAAWEDDSGDGIDADGDRNETESAAKTGKSRHGKWESGKGRCPVTGRRVLGGTEGLRRVLI
What is the function of this protein?
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane.  PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10.  When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation.
What are the official names of this protein?
Peroxisome assembly protein 12, Peroxin-12.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: ASSY_ECOK1
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENLENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_GRAFK
Sequence: MAKDIKFDIQARNGIKRGVDALANAVKVTLGPKGRNVIISKSFGAPTVTKDGVTVAKEIELEDPLENMGAQMVKEVASKTNDLAGDGTTTATVLAQAIVQEGLKNVAAGANPMDLKRGIDKAVEALTADLAKQTKEVGDSSEKIKQVASISANNDDMIGDLIAQAFGKVGKEGVITVEEAKGTETHVDVVEGMQFDRGYLSPYFVTNSEKMTADLEDPYILLFDKKISSMKDLLPVLEPVAQSGKPLLIIAEDVDGEALATLVVNKLRGSLKIAAVKAPGFGDRRKAMLEDIAILTGGTVISEERGFSLENATIDMLGTAEKVAIDKDNTTVVNGAGDDKAIKERVNQIKAQIESTTSDYDREKLQERLAKLAGGVAVLYVGAASEVEMKEKKDRVDDALHATRAAVEEGIVAGGGVALIRAQVVLSKIKTENPDEATGVKIVSKAIESPLRTIVENAGGEGSVVINKVLEGKKDFGYDAKTETYVDMLKAGIIDPKKVTRVALENAASVAGMILTTECALTDIPEDNAGGGGMPQGMGGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDHP_MESCR
Sequence: MAVAELSPSYKTQLKTCQQLSSSLSTRLSDHRKFSLRLLPRPVSVRGGIRCSVAPNQVQAPVAVPAEGQTGKPECYGIFCLTYDLKAEEETKTWKKMITIAVSGAAGMISNHLLFKLASGEVFGPDQPIALKLLGSERSFNALEGVAMELEDSLYPLLRAVSIGIDPYDIFQDAEWALLIGAKPRGPGMERADLLDINGQIFAEQGKALNAVASRNVKVIVVGNPCNTNALICLKNAPNIPAKNFHGLTRLDENRAKCQLALKAGVFYDKVSNMTIWGNHSTTQVPDFLNAKIDGLPVKTVIKDHKWLEEEFTVMIQKRGGALIQKWGRSSAASTAVSIADAIKSLVTPTPEGDWFSSAVYTNGNPYGIAEDLVFSMPCRSKGDGDYELVKDVVFDDYLRQRIKKSEEELLAEKRCTAHLTGEGVAVCDLPAGDTMLPGEM
What is the function of this protein?
The chloroplastic, NADP-dependent form is essential for the photosynthesis C4 cycle, which allows plants to circumvent the problem of photorespiration.  In C4 plants, NADP-MDH activity acts to convert oxaloacetate to malate in chloroplasts of mesophyll cells for transport to the bundle sheath cells.
What are the official names of this protein?
Malate dehydrogenase [NADP], chloroplastic, NADP-MDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRH_BRADU
Sequence: MTDPVYRRVVIKLSGEYLAGQQGFGIDQPTVDRVADDLIAARHLGTEVAVVIGGGNIVRGVEVSSRGVSRPTGDTMGMLATMMNCLALEAAIERKGTPARTLSAFVMPEISELFTRTAAHKYLAEGRIVLLGGGTGNPFFTTDTTAVLRAAEIGAQAVLKATNVDGVYSADPKKDPTATRFDRLTHSQAIEGGYKVMDATAFALARETSLPIIVFSIAEPGSIGAILRGIGHGTIVAG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_POLNS
Sequence: MRLILLGAPGAGKGTQAQFICEKFAIPQISTGDMLRAAVKARTELGVAAKKIMDAGGLVSDDIIIGLVKDRLTQPDCSKGYLFDGFPRTIPQAQVMKDAGVPIDYVLEIDVPFDAIIDRMGGRRVHLASGRTYHIKFNPPKVEGKDDITGDPLIQRDDDKEETVRKRLQVYDDQTRPLVEYYSSWAAQANPADKVKAPTYRKVSGTSSVEDITASIFAALK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_STAA9
Sequence: MNDLIINHIAELILPKSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGQHTDDYDATETIDASGKVVSPALVDAHTHLTFGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLKVSNRLAEKYDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVKIHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTFYLGKEDYADARGMLDNNGAIALATDYNPGSSVTNNLQLVMAIAALKLKLSPSEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDGKVIVDNTLSFKA
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_BUCBP
Sequence: MKVYKLVLMRHGESIWNELNKFTGWHDVDLSNRGVQESLKAAKLLKKHGFYFDYAYSSVLKRSIHTLWNIIKFLDQSWIPVKKSWRLNERHYGALEGLNKDDVIQKYGNDKVQQWRRSFNIAPPKISYLEKKKLAHDSRYNNINFDILPYCESLKLTTQRVLPYWLNEIFPRFQKNTKIIIVAHGNSLRALIKYLNNINDIDILNLNIATGFPIIYEFNSEFKPIQYYYLKQ
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: SLMA_ECOL6
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLASQLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: COX1_DROYA
Sequence: SRQWLFSTNHKDIGTLYFIFGAWAGMVGTSLSILIRAELGHPGALIGDDQIYNVIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPALSLLLVSSMVENGAGTGWTVYPPLSSGIAHGGASVDLAIFSLHLAGISSILGAVNFITTVINMRSTGITLDRMPLFVWSVVITALLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIISQESGKKETFGSLGMIYAMLAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVPTGIKIFSWLATLHGTQLSYSPAILWALGFVFLFTVGGLTGVVLANSSVDIILHDTYYVVAHFHYVLSMGAVFAIMAGFIHWYPLFTGLTLNNKWLKSQFIIMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYTTWNVVSTIGSTISLLGILFFFYIIWESLVSQRQVIYPIQLNSSIEWYQNTPPAEHSYSELPLLTN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ENO_AERPE
Sequence: MGVNDFAIERVWGLQVLDSRGNPTVKAYVKLAGGSLGWGIAPSGASRGEREAVELRDGGGKWRGKGVSRAVSLLNTVVAPRLEGVDARRQAQIDRLLIELDGTPNKSRLGGNTTTALSIAVSRAAAAQARLELFQYLGGAGARRLPIPLLNVINGGVHAGNELDFQEFMIIPYGFESFTEAMRAAVETYGELKSLLKDRYGASAVNVGDEGGFAPPMRSAEEALKTLVDAVEKAGYQPGSEIALGIDAAASQLYSNGRYSVEGKSLSREELLSLYQRLVEQYPIVYLEDPFSEDDYEGFKAAVDALSTETIIVGDDLLVTNPQRVKEASALKAVTGLLVKVNQVGTLTEALEAIQAARDRGIVHIVSHRSGDTEDTFIADLAVATEALMIKTGAPARGERTSKYNRLLEIENILGYSAEYAGPELRGVMGRR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ATPL_BACHK
Sequence: MSLGVIAAAIAIGLSALGAGIGNGLIVSRTIEGVARQPELKGALQTIMFIGVALVEALPIIGVVIAFIVMNK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PP1RA_MACMU
Sequence: MGSGPIDPKELLKGLDSFLNRDGEVKSVDGISKIFSLMKEARKMVSRCTYLNILLQTRSPEILIKFIDVGGYKLLNNWLTYSKTTNNIPLLQQILLTLQHLPLTVDHLKQNNTAKLVKQLSKSSEDEELRKLASVLVSDWMAVIRSQSSTQPAEKDKKKRKDEGKSRTTPPERPLTEVKAETRAEEAPEKKREKPKSLRTTAPSHAKFRSTGLELETPSLVPVKKNASTVVVSDKYNLKPIPLKRQSNVAAPGDATPPAEKKYKPLNTTPNATKEIKVKIIPPQPMEGLGFLDALNSAPVPGIKIKKKKKVLSPTAAKPSPFEGKTSTEPSTAKPSSPEPAPPSEAMDIDRPGTPVPPVEVPELMDTASLEPGALDAKPVESPGDPNQLTRKGRKRKSVTWPEEGKLREYFYFELDETERVNVNKIKDFGEAAKREILSDRHAFETARRLSHDNMEEKVPWVCPRPLVLPSPLVTPGSNSQERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGSGMGSGHRPHEGPGSSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPHEHRGHDGPGHGGGGHRGHDGGHSHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP
What is the function of this protein?
Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex.  The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.  Mediates interaction of WDR82 and PPP1CA.  Inhibitor of PPP1CA and PPP1CC phosphatase activities.  Has inhibitory activity on PPP1CA only when phosphorylated.  Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 1 regulatory subunit 10, MHC class I region proline-rich protein CAT53.
What are the subcellular locations of this protein?
Nucleus. Note=Found in discrete nucleoplasmic bodies and within nucleoli. Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase (By similarity).
Protein: HSLJ_ECOLI
Sequence: MKKVAAFVALSLLMAGCVSNDKIAVTPEQLQHHRFVLESVNGKPVTSDKNPPEISFGEKMMISGSMCNRFSGEGKLSNGELTAKGLAMTRMMCANPQLNELDNTISEMLKEGAQVDLTANQLTLATAKQTLTYKLADLMN
What are the official names of this protein?
Heat shock protein HslJ.
Protein: COXX_CYAP4
Sequence: MQETSLTKAVSPRQSLGQILLNYYQLTKPRLIVLFLITTAAGMWVAARGEVDPVLALITLLTGAMAAGSANTINCLYDRDIDYIMERTRHRPLPSGRVQPWEALVFAIALAVGAFSLQTLCANLLSACLEMAGIAVYVGVYTHWLKRSSTQNIVIGGAAGAIPPLVGWAAVTGELSWAAWVLFAIIFIWTPPHFWPLAMLIQEDYAKVNVPMMPVVDGDRPTAWQIFGYTLVLLPTTLLLVYPLHACGLIYGAIALVLGVVFIRKAWELVQTPEDKDQARAVFKFSILYMMILCAAMGIDSLPLTHAVVSQVTANLQTLVGTIL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS24_NANEQ
Sequence: MAKYSIIMEKKNKLFDRTEYIIQVEHPKEKTPTREEAKEKIAEMLNVDKNKLVIKKIVSKYGLPYSFIYARVYDNIDTAKRVELKQILRRNNLQ
What are the official names of this protein?
30S ribosomal protein S24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: EPSF_BACSU
Sequence: MNSSQKRVLHVLSGMNRGGAETMVMNLYRKMDKSKVQFDFLTYRNDPCAYDEEILSLGGRLFYVPSIGQSNPLTFVRNVRNAIKENGPFSAVHAHTDFQTGFIALAARLAGVPVRVCHSHNTSWKTGFNWKDRLQLLVFRRLILANATALCACGEDAGRFLFGQSNMERERVHLLPNGIDLELFAPNGQAADEEKAARGIAADRLIIGHVARFHEVKNHAFLLKLAAHLKERGIRFQLVLAGDGPLCGEIEEEARQQNLLSDVLFLGTEERIHELMRTFDVFVMPSLYEGLPVVLVEAQASGLPCIISDSITEKVDAGLGLVTRLSLSEPISVWAETIARAAAAGRPKREFIKETLAQLGYDAQQNVGALLNVYNISTEKDHNR
What is the function of this protein?
May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation.  EPS is responsible for the adhesion of chains of cells into bundles.  Required for biofilm maintenance.
What are the official names of this protein?
Putative glycosyltransferase EpsF.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: RP28_BACTK
Sequence: MSLFAAIGYMVREVFVFVSYVKNNAFPQPLSSDDERKYLELMEQGDAQARNLLIEHNLRLVAHIVKKFENTGEDAEDLISIGTIGLIKAIESYSAGKGTKLATYAARCIENEILMHLRVLKKTKKDVSLHDPIGQDKEGNEISLIDILKSESEDVIDMIQLSMELEKIKEYIDILDEREKEVIVKRFGLGLDKEKTQREIAKALGISRSYVSRIEKRALMKMFHEFVRAEKEKKAKE
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor directs the transcription of crystal protein genes, a sporulation-regulated event.
What are the official names of this protein?
RNA polymerase sigma-28 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family.
Protein: NTPPA_SHIBS
Sequence: MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAHKKAQAGVAQTAQDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQVMTAVVLADSQHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFVRKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHA_ECOL6
Sequence: MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVASGAVKPLMRNLIIADNVHGESGLDGPALPEPTFAPQNCTAVELMAKTLRESEEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVVDYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA
What is the function of this protein?
Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: DYAD_ARATH
Sequence: MSSTMFVKRNPIRETTAGKISSPSSPTLNVAVAHIRAGSYYEIDASILPQRSPENLKSIRVVMVSKITASDVSLRYPSMFSLRSHFDYSRMNRNKPMKKRSGGGLLPVFDESHVMASELAGDLLYRRIAPHELSMNRNSWGFWVSSSSRRNKFPRREVVSQPAYNTRLCRAASPEGKCSSELKSGGMIKWGRRLRVQYQSRHIDTRKNKEGEESSRVKDEVYKEEEMEKEEDDDDGNEIGGTKQEAKEITNGNRKRKLIESSTERLAQKAKVYDQKKETQIVVYKRKSERKFIDRWSVERYKLAERNMLKVMKEKNAVFGNSILRPELRSEARKLIGDTGLLDHLLKHMAGKVAPGGQDRFMRKHNADGAMEYWLESSDLIHIRKEAGVKDPYWTPPPGWKLGDNPSQDPVCAGEIRDIREELASLKRELKKLASKKEEEELVIMTTPNSCVTSQNDNLMTPAKEIYADLLKKKYKIEDQLVIIGETLRKMEEDMGWLKKTVDENYPKKPDSTETPLLLEDSPPIQTLEGEVKVVNKGNQITESPQNREKGRKHDQQERSPLSLISNTGFRICRPVGMFAWPQLPALAAATDTNASSPSHRQAYPSPFPVKPLAAKRPLGLTFPFTIIPEEAPKNLFNV
What is the function of this protein?
Required for fertility.  Involved in chromatid cohesion establishment, in chromosome structure during male and female meiosis (e. g.  the synapse formation between homologous chromosomes, the recombination, and the cohesion of both chromatid arm and centromere), and in axial element formation.  Regulates the switch from mitosis to the reductional meiosis division of megaspores prior to the female gametogenesis (megasporogenesis).
What are the official names of this protein?
Protein DYAD, Protein SWITCH 1.
What are the subcellular locations of this protein?
Nucleus. Note=Localized in meiocyte nuclei just before meiosis, exclusively in meiotic G1 and S phase (at protein level).
Protein: SHU2_VANPO
Sequence: MDTNKSVIYSQFFSKLINDNNEMDDTMTSFLYYLFPRELFIRALSLLDSGDMFIYVLENGNISSSSMNLVPTVCDSDESRSPSSSGNSNNEASNESNTIDSNSIVEELYDIDTELQNRLIVKTHEKDSPPIYVDLKTWFCSCDEFNSYFNLELQKNQSIPIQDTLIRNIDDIQEFSEDKFAQIDAHSLSKQKYVCHEKLMCPHLLAYSILLASSTKTLRYFTLVNQTVLLIRISNMDEWLKLHINIVS
What is the function of this protein?
Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase.  Required for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation (By similarity).
What are the official names of this protein?
Suppressor of hydroxyurea sensitivity protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHU2 family.
What are the subcellular locations of this protein?
Nucleus.