PharMolix/UniProtQA huggingface dataset:
Protein: RDRP_TYYVF
Sequence: MYSKLMFFFALCSISFLFTSEAASTMLLESSYLPLNQSYAPGFLYKRDMLPPPLQAVLTYTCPEPRPLAEESYNDLLRAISQKSSSDFQNAYSLALSFSSDFYQHGLKTLKDVSFLAVEKFLWGLTRLWSSLILASFSALWWLVSNFTTPVFCLALLYTVTKYMVKTVSFLFGGLPIWIISIAFSLLKKSFSALRSTPKCLYEKAIDGFKSFTIPQSPPKSCVIPITHASGNHAGYASCIKLYNGENALMTATHVLRDCPNAVAVSAKGLKTRIPLAEFKTIAKSDKGDVTLLRGPPNWEGLLGCKAANVITAANLAKCKASIYSFDRDGWVSSYAEIVGSEGTDVMVLSHTEGGHSGSPYFNGKTILGVHSGASATGNYNLMAPIPSLPGLTSPTYVFETTAPQGRVFAQEDIAEIEGLYAQVMKRVQQAEDFKPKTGKYWGDMEDDEDIFFESKEDLSGKRSARHRPRNKRRRQLHPKDKQRRWERDDGENNLISSGKDKSREHREESDRGDLRESDENSEIPPQKSPKETAGEFERYFSSLYNWEVPTSPREVPGFRHCGKLPQYYHPKQKEESSWGKTLVGNHPALGEKTSGFGWPKFGPEAELKSLRLQASRWLERAQSAEIPSDAERERVIQKTADVYHPCQTNGPAATRGGTLTWNNFMIDFKQAVFSLEFDAGIELPYIAYGKPTHRGWVEDQKLLPILAQLTFFRLQKMLEVNFEDMGPEELVRNGLCDPIRLFVKGEPHKQAKLDEGRYRLIMSVSLVDQLVARVLFQNQNKREIALWRAIPSKPGFGLSTDEQVLDFVESLARQVGTTTTEVVANWKNYLTPTDCSGFDWSVADWMLHDDMIVRNRLTIDLNPATERLRSCWLRCISNSVLCLSDGTLLAQIHPGVQKSGSYNTSSSNSRIRVMAAFHTGAIWAMAMGDDALESNPADLAAYKKLGFKVEVSGQLEFCSHIFRAPDLALPVNENKMIYKLIYGYNPGSGNAEVVSNYLAACFSVLNELRHDPASVELLYSWLVDPVLPQKIPGE
What is the function of this protein?
Precursor from which the RNA-dependent RNA polymerase (RdRp) is probably released.  RNA-dependent RNA polymerase plays an essential role in virus replication (Potential).
What are the official names of this protein?
Protein P1-P2.
What are the subcellular locations of this protein?
[Protein P1-P2]: Membrane; Multi- pass membrane protein.
Protein: Y633_HAEIN
Sequence: MLWDLSGGMVDQRFLVILCMVAFLAGCTQSPVTASVIVMEMTGAQPVLIWLLISSIIASIISHQFSPKPFYHFAAGCFLQQMQARQAEELRSKTEQEK
What are the official names of this protein?
Uncharacterized protein HI_0633.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NKX31_MOUSE
Sequence: MLRVAEPREPRVEAGGRSPWAAPPTQSKRLTSFLIQDILRDRAERHGGHSGNPQHSPDPRRDSAPEPDKAGGRGVAPEDPPSIRHSPAETPTEPESDAHFETYLLDCEHNPGDLASAPQVTKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSEDLGVLEKNSPLSLPALKDDSLPSTSLVSVYTSYPYYPYLYCLGSWHPSFW
What is the function of this protein?
Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity).  Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate (PubMed:10215624).  Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells (PubMed:12036903).  Plays a role in the formation of minor salivary glands (particularly palatine and lingual glands) (PubMed:10906459).
What are the official names of this protein?
Homeobox protein Nkx-3.1, Homeobox protein NK-3 homolog A.
What is the protein family that this protein belongs to?
Belongs to the NK-3 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRM6_SCHPO
Sequence: MLRHASTISENSSVFIKLPSDNVRFVTLKPNNTIHLGKFGSFLADDLFGKHFDETFEIYQPKKIRVLKTREVQYIEEEKKTNQELNDCRGNQLMTQEEIDELRANIKAGGLRAEEAIKQLTNSSKTFEQKTLFAQEKYVTRKGEKYLQRFQVLRPCVEVVANYMIEHDPYKILDLTAECISLMLTLGNVKPGGRYLVVDETGCMFLGSLIDRVAGDCKITLVHPNEQPNSSCLEYWGQDFKEDSLVQKGILKTLNWYQVTNPTETLSEYSVEDIPESELNEMKLRHRKRYETKKATFNRLKNTIDDFESGNYDALFILSIHTPMSVLQHLLPKLGISRPFMVYSTYQQVLVETYHQLSKWDNLFVEKTAQSTENDEKVDQGDVAIDTQKEKVIMLDIHEIRTRPYQVLPERTHPFMTVRGDMGFVLSGIKVLTSDSNLAAGRFPKRKGQKETSSVKKAKLEN
What is the function of this protein?
Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit trm6, General control non-derepressible protein 10, Protein gcd10, tRNA(m1A58)-methyltransferase subunit trm6, tRNA(m1A58)MTase subunit trm6.
What is the protein family that this protein belongs to?
Belongs to the TRM6/GCD10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPP_LISIN
Sequence: MNLIPTVIEQTSRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLDAQDPEKDIFLYINSPGGSISAGMAIYDTMNFVKADVQTIGMGMAASMGSFLLTAGANGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILKIKERMNTIMAEKTGQPYEVIARDTDRDNFMTAQEAKDYGLIDDIIVNKSGLKG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_SULIM
Sequence: MTKFETVRGMKDYIGIDAEKIRYLESTFRDLAIKYGYSEIITPVVEEFKLFALKGGEELRETMYVFKDKADRELSLRPEITPSVARAYIQNLQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADLEVLDLLYNFYDKLNLSNDITIKINNIGIFRKIMDKYNIEDNLQEHILHLIDKNKINEALDILEKNLKNKDIIDFFNKILTKKDTKLEDIESLAELEEVSRLDIKSEFLYLFRLSRILSNLNIKFKIDLGFVRGLAYYTGLIFEVLHPSVQFSIAGGGRYDKLIELYGGLPSPAIGFAIGVERTLLVIKDLKVEEPVNVIVIGMSEDTIPSMFMVSRILRKEEYKVVINTKDQPLSKLLPYYASQGFKVAIIIGKQELEKNMITVRNLITRKQISVPLENIEDAIKQTL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_MAIZE
Sequence: EKVCADLVKGAKDKHLRVKGPVRIPTKVLHITTRKSPCGEGTNTWDRFEFRIHKRVIDLI
What are the official names of this protein?
40S ribosomal protein S20, S22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MINC_CLOBA
Sequence: MHKDGVLIKGNREGINATIDMEKFSSFEDMLNMLIKKLSKGKHFYKGTTLILNINLSLIKKNDIKKLKESLLNEIELNEIIFEQLELEEESNKQTKIFNGVYEGKTKFIRRTVRSGQCLNYPGNIVIIGDVNSGAEVHAGGNIIVLGSLKGSVNAGNTGNKKSIIAAFLLEPEILKIADVITISPDGLEKPKYPEIAKVKDGTIIVEPYLANKYI
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: CLPP_ORYSA
Sequence: MPIGVPKVPYRIPGDEEATWVDLYNVMYRERTLFLGQEIRCEVTNHITGLMVYLSIEDGISDIFLFINSPGGWLISGMAIFDTMQTVTPDIYTICLGIAASMASFILLGGEPTKRIAFPHARIMLHQPASAYYRARTPEFLLEVEELHKVREMITRVYALRTGKPFWVVSEDMERDVFMSADEAKAYGLVDIVGDEMLDEHCDTDPVWFPEMFKDW
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: Y681_ENTFA
Sequence: MSNIYDTANQIERELRELDEFKALQAAYEEVKADEAAYTLFKEFQGFQQGLQEKQMRGEEFTDEDAEKAQSIATKVQETAVINELMQKEQAFSLVVNDLNRIIMTPVRDMYND
What are the official names of this protein?
UPF0342 protein EF_0681.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: DTD_ALCBS
Sequence: MKVLMQRVSEAHVDVSGRTVGAIDNGLLLFIGIEKHDDTALVDRMVERIIGYRVFADERGKMNWDVRDAGGALLAISQFTLVADTRKGRRPSFSSAADPVLARPLYEHCVAQLKAHGLPVATGVFAAEMQVSLVNDGPVTFMLEM
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T4S1_MESAU
Sequence: MCSSKCTRYIGHSLVVFAVLCIVANILLYFPNGETKYAYEDHLSRFVWFFAGIVGGGLLILLPAFVFLGLEGEDCCGCWSCENYGKRCTMLSSIMAALIGIAGSGYCVIVAALGLAEGPKCGDSHGMWNYTFANTDGQYLLDPTTWSKCHEPNNIVEWNVTLFSILLALGGLEFILCLIQVINGVLEGMCSYCCSHQQQYDC
What are the official names of this protein?
Transmembrane 4 L6 family member 1, MM3, Tumor-associated antigen L6 homolog.
What is the protein family that this protein belongs to?
Belongs to the L6 tetraspanin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Colocalizes with SDCBP2 in the apical region of the cell.
Protein: SPG7_RAT
Sequence: MAAALLLLRALRQSPEPGPWRLWAQLSGRSPGLFSGAGGRRPYVVRGTPIGLAAAGGHTPQSLLLRILTPSFEGVSGLLLKRHIVPSAIRLWQLSGSTLYFNTSGLKQKNKDDDKPKGKAPEDDEEERRRKEREDQMYRERLRTLFIIAIVMSLLNSLSTSGGSISWADFVNEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIESKDRIPVSYKRTGFFGNALYALGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKTGKGVSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSNTEEEQTLNQLLVEMDGMGTADHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIFEQHLKGLKLTQPSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTFNFEYAVERVIAGTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIAYSMVKQFGMAPSIGPVSFPEAQEGLVGIGRRPFSQGLQQMMDHEARLLVARAYRHTEKVLLDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQKWIDAEKEKQASGEEEAPAP
What is the function of this protein?
ATP-dependent zinc metalloprotease.  Plays a role in the formation and regulation of the mitochondrial permeability transition pore (mPTP) and its proteolytic activity is dispensable for this function (PubMed:26387735).
What are the official names of this protein?
Paraplegin.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CTU2_ANOGA
Sequence: MCSIVEDDFGDEGGAHAMKEDTPQPELGGNELCRKCNTEQAVLKLNQKEPQCRVCFLNYVRHKFRASLGSTKIVRRGSRVLIILTGEPANVTLLDMVRFGLEQDAFKQLRIVPVLLYVDDDFVGNTSEARLQQLAERLQVFKQFESFPAYYTVCGSSRHVALTFDGAFSPAGFEQDEARLLQVLDAVRSVSSKQDLLEQVRKQTYRQIGHALQCAYVFLSDIGVDLAKTLLSNVALGRGCSLAQDVAFCDDRYNTVKLVRPIRDLNPDEVSNYLQYSEQPLLSYSPAKHFEDKPSLQNLTAKFIDNLMQSFPSTVSTVYRTGDKLDAPKAARNECCRFCGAALDYRGSKTLFATEYSRLVSSRINAACSHEDILLKSKQMELDAERAVNGEDDQGEERVLMKQLCHGCRNIFEDLNK
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPR_HV1MP
Sequence: MEQPPEDQGPQREPYNEWTLELLEELKNEAVRHFPREYLHGLGQYIYNTYGDTWRGVETMIRILQQLLFIHFRIGCHHSRIGIIRQRRLRNGSSRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: PYCR1_BURCM
Sequence: MSESLAEVVLSLDEVHALALRVLTHNGMSAAHAQAIANVITQGQRDECHSHGVYRLLVCVRSLKKGKVDPQAVPTLRRLSSSIVAVDAHRGFSLLSFETGLPVLVEMAKQHGIAAMAINHCYHFSALWPEVEAIAAEGLVGIAMNPSHSWVAPEGGREPVFGTNPIAFAWPRPDGVPFVFDFATSAIARGDIELHAKQGKAIPPHWAIDADGQPTTDPKAALQGAMRTFGGHKGSALAAMVELLGGALIGDMTSRESMAFDEGVGATPCHGELVIAFDPKVFLGDELDAGLARGERMFASITGQGARLPSQRRFDARARSIAHGVRIPKALYDEILTLLD
What is the function of this protein?
Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor.  May be involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline.
What are the official names of this protein?
Delta(1)-pyrroline-2-carboxylate reductase 1, Pyr2C reductase 1, Proline ketimine reductase 1.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family.
Protein: ATPG_XANC5
Sequence: MAGGREIKTKIKSVQNTRKVTRALEMVSASKIRKAQERMKTSRPYAQAMKQVIGHLAQASTDFQHPFLVEREQVKRVGYIVISSDRGLAGGLNNNLFRKMLGEVRPWQDTGAEIDVVTIGQKASAFFRRIKVNMVGSVTHLGDSPQVEQLIGVIKVMIDAFIEGKVDRVYLVYNRFVNTMTQKASFDQLLPLPAAEHKVAHHDWDYLYEPDAATVLEHVMTRYIESLVYQAVLENVASEHAARMVAMKAASDNANKMIGTLQLVYNKARQAAITQEISEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IHFA_PSESM
Sequence: MGALTKAEMAERLYEELGLNKREAKELVELFFEEIRHALEDNEQVKLSGFGNFDLRDKRQRPGRNPKTGEEIPITARRVVTFRPGQKLKARVEAYAGTKS
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: A16L1_PONAB
Sequence: MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPTTALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDSRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKHWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYTWSVLTGKVEKVLSKQHSSSINAVAWSPSGLHVVSVDKGCKAVLWAQY
What is the function of this protein?
Plays an essential role in both canonical and non-canonical autophagy: interacts with ATG12-ATG5 to mediate the lipidation to ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAPL1, GABARAPL2 and GABARAP).  Acts as a molecular hub, coordinating autophagy pathways via distinct domains that support either canonical or non-canonical signaling.  During canonical autophagy, interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to ATG8 proteins, to produce a membrane-bound activated form of ATG8.  Thereby, controls the elongation of the nascent autophagosomal membrane.  Also involved in non-canonical autophagy, a parallel pathway involving conjugation of ATG8 proteins to single membranes at endolysosomal compartments, probably by catalyzing conjugation of phosphatidylserine (PS) to ATG8 (By similarity).  Non-canonical autophagy plays a key role in epithelial cells to limit lethal infection by influenza A (IAV) virus (By similarity).  Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production.  Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response.  Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway.  Plays a role in regulating morphology and function of Paneth cell (By similarity).
What are the official names of this protein?
Autophagy-related protein 16-1, APG16-like 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ATG16 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Note=Recruited to omegasomes membranes by WIPI2. Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. Localizes also to discrete punctae along the ciliary axoneme (By similarity). Upon activation of non-canonical autophagy, recruited to single-membrane endolysosomal compartments (By similarity).
Protein: CYSJ_BUCAI
Sequence: MKNQNKFDPVFPLSSEQLNNLKELERTCTNIQSAWLSGYFWKIANQTSNITSFQTNESEKNDPVITIISASQTGNAKLLSKRLYEYFNKNNKISRLIDAMDYKFKKIKDEKILILIISTQGEGEPPEEALSFYKFIMSKNAPNLNNLYYSVFGLGDTSYNLFCQAGKDFDKRFKELGGNSLLDRFDADIEYEDNYNKWSQDLLQSINSKEKIYKSSVSYIDQENTLILSKNHYTKKNPAEGIILTNQKITGRNSKKDVHHIEIDISNLNIKYSPGDALGVWYKNDSNLVKNILELLSINISETITIKNDVITIFDALQNHFELTNNTKNIIKSYANFSKNKFLKDIISNDSDLENYTINTPLIKMIHDHPLKLSSQQLIGLLRPLTPRLYSISSSQEEIDNEIHITVGVVKKLISGHVYLGGASGYLSQSLKSDDIIKIFIQTNDNFRLPINKNTPIIMISSGTGIAPFRAFMQQRDNDNADGKNWLFFGNPNFTEDFLYQVEWQKYIKKGLITNMNLAWSQDQKNKIYVQDRIRENSQEIWSWIEEGAQIYVCGNASKMAKDVEKALLDIISHNAHLNLEESQEFLNNLRLNKRYKRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: FOLD_RICPU
Sequence: MNNIIDGKALANEILADLKLEIQELTSHTNASPKLAIVLVGDNPASIIYVRNKIKNAHKIGIYTVLINLSATIHTNDLISKINELNLDNEISGIIVQLPLPSSIDKNKILSAVSPSKDIDGFHPLNVGYLHSGISQGFIPCTALGCLAAIKKYEPNLTGKNVVIIGRSNIVGKPLSALLLKENCSVTICHSKTHNLRSITSKADIVVAAIGSPLKLTAEYFNPESIVIDVGINRISSNKIIGDVDFENVQSKVQYITPIPGGIGPMTIAFLLKNTVKAFKDSLYTLDT
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SSB_BPPZA
Sequence: MENTNIVKATFDTETLEGQIKIFNAQTGGGQSFKNLPDGTIIEATAIAQYKQVSDTYGDAKEETVTTIFAADGSLYSAISKTVAEAASDLIDLVTRHKLETFKVKVVQGTSSKGNVFFSLQLSL
What is the function of this protein?
Single-stranded DNA binding protein required for the elongation during viral DNA replication by strand displacement.  Displaced viral DNA strands are transiently coated with the ssDNA-binding protein and therefore protected againt nucleases.  The latter is then probably removed by the replisome that performs lagging strand synthesis or during the events that lead up to the recombination process.  Has helix-destabilizing activity since it removes secondary structure from the ssDNA in replicative intermediates.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB, Gene product 5, gp5, Protein p5.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus single-strand-binding protein family.
Protein: SYRC_CRIGR
Sequence: MDGLVAQCSARLLQQEKEIKSLTAEIDRLKNCGHLEDSPSLDQLREENLKLKYRLNILQRSLQAEKRRRPTKNMININSRLQDVFGCAIKAAYPDLDNPPLVVTPSQQPKFGDYQCNSAMGISQMLKAKEQKVNPRGIAENITKHLPNNEYIDRVEIAGPGFINVHLRKDFVSEQLTNLLVNGIQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESMSRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDQFPDYLTVSPPIGDLQAFYKESKKRFDTEEEFKKRAYQCVVSLQSKDPDFIKAWNLICDVSRAEFNKIYDALDITLIERGESFYQDRMKDIVKEFEDKGYVQVDDGRKIVFVPGCSIPLTIVKSDGGFTYDTSDLAAIKQRLFEEKANKIIYVVDNGQAVHFQTIFAAAQMIGWYDPKVTQVTHVGFGVVLGEDKKKFKTRSGETVRLVDLLGEGLKRSMDKLKEKERDKVLTEEELTAAQTSIAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANVDEEMLQKAARETKIVLDHEKEWKLGRCILRFPEILQKMLDDLFLHTLCDYIYELATTFTEFYDSCYCVEKDRQTGKVLKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM
What is the function of this protein?
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.  Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.
What are the official names of this protein?
Arginine--tRNA ligase, cytoplasmic, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol.
Protein: METN_HALH5
Sequence: MISLDGIRKVFKAKRGSVTAVDGVNLKINEGEIFGVIGYSGAGKSTLIRMLNMLERPTEGSVIVAGKDLSKLSDRDLRIERQKIGMIFQHFNLLWSRTVRKNIAFPLEIAGVPKKEREKRVDELINLVGLEGREEAYPSQLSGGQKQRVGIARALANNPKVLLCDEATSALDPKTTDSILDLLVDINEKLGLTIVLITHEMHVIRKICHRVAVMEAGKVVEEGPVLDVFRKPKEHITKEFVKQVTEPEETVQHLLNEVKSGRIVQLTFVGESAEKPLITNLIRTFAVDVNILQGKISKTQEGSYGTLFIHLDGPKDEIEKAITYMHEQQLELEVIAGA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
Protein: T2R39_HUMAN
Sequence: MLGRCFPPDTKEKQQLRMTKLCDPAESELSPFLITLILAVLLAEYLIGIIANGFIMAIHAAEWVQNKAVSTSGRILVFLSVSRIALQSLMMLEITISSTSLSFYSEDAVYYAFKISFIFLNFCSLWFAAWLSFFYFVKIANFSYPLFLKLRWRITGLIPWLLWLSVFISFSHSMFCINICTVYCNNSFPIHSSNSTKKTYLSEINVVGLAFFFNLGIVTPLIMFILTATLLILSLKRHTLHMGSNATGSNDPSMEAHMGAIKAISYFLILYIFNAVALFIYLSNMFDINSLWNNLCQIIMAAYPASHSILLIQDNPGLRRAWKRLQLRLHLYPKEWTL
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 39, T2R39, Taste receptor type 2 member 57, T2R57.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y3646_BRUA2
Sequence: MKRRTFLAMSLALTFLPSVALADNIPVRVGYIADYWGTSITAIASEKGLWEKHGLDADTRVFTNGPIQVQALGAGSLDFGYIGPGALWLPASGKAKIVAINSVGFSDRVIAQEGFKSMADLKGKKIGVPEGTSGDMLLRLALGKAGMKLDDVQVIKMDPSTVVSAFASKQIDAAGIWYPLIGTIKEHVPGMVELAANSDFFPDKTFPSAFIARNEIVAENPEAVKRMIAVIEEAEDFRTANPEQSVDITAKFLKVDKANLETEAKNGKSLTSEELVKLTRDGSVNGWLSGMADMFVTFGKLKSPLDPKDYYLADYFTAK
What is the function of this protein?
Probably part of an ABC transporter complex.
What are the official names of this protein?
Putative binding protein BAB2_1146.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein SsuA/TauA family.
What are the subcellular locations of this protein?
Periplasm.