PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_PSEA6
Sequence: MQHKHIRNFSIIAHIDHGKSTLSDRLIQHCGGLSEREMSAQVLDSMDIERERGITIKAQSVTLNYKARDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIDLNMEVVPILNKIDLPQAEPDRVAEEIEDIVGIDAIDAVRCSAKTGIGIEDVLEVIVRQIPPPEGDIDAPLKALIVDSWFDNYQGVVSLVRIVQGELRKNDKIKIMSTGVVHQADKVGIFTPKATDTGILRAGEVGFIVAGIKEIHGAPVGDTITLARAPADAALPGFKKVKPQVYAGLFPISSDDYEDFRDALAKLSLNDASLFFEPESSSALGFGFRIGFLGMLHMEIIQERLEREYDLDLITTAPTVVYEVVTTDGETLYVDNPSKLPPVNSIDEIHEPIVEAHILVPQEYLGSVITLCVDKRGVQTSMTYHGKQVAVTYELPMAEVVMDFFDKLKSTSRGFASLDYNFKHFQTAEMSRLDILINGERVDALAMITHKDNAQSRGRDLVEKLRELIPRQMFDIAIQAAIGNQIVARSTIKQLRKNVIAKCYGGDVSRKKKLLQKQKDGKKRMKSVGNVELPQEAFLALLKVGK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VIP1_DROME
Sequence: MSYTELESGYQDISQQHQQQNPHQSQPQQRVGFYLGLQDGNGDTDFGDSNDGMDSDTSTSSSNSKQVVVGICAMAKKTQSKPMKEILTRLGEFEFIKLVTFEENVILREPVQNWPTCDCLVSFHSKGFPLEKAIEYAQLRNPFVLNNLHMQYDIQDRRRVYAILEKEGIEIPRYAVLDRDSPDPKHHELIESEDHVEVNGITFNKPFVEKPVSAEDHNIYIYYPTSAGGGSQRLFRKIGSRSSVYSPESRVRKTGSFIYEDFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVILNHSEKLISRKVCLAFKQTVCGFDLLRANGKSYVCDVNGFSFVKNSNKYYDDCAKILGNMILRELTPTLHIPWSVPFQLDDPPIVPTTFGKMMELRCVVAVIRHGDRTPKQKMKVEVRHPKFFEIFEKYDGYKLGHVKLKRPKQLQEILDIARFLLSEIHTKAHAEIEEKESKLEQLKNVLEMYGHFSGINRKVQMKYQPKGRPRGSSSDDTNLAADQPVEPSLVLILKWGGELTPAGRIQAEELGRIFRCMYPGGQGRSDYSGTQGLGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANTNGLLDNDCDSSKYQNLAKGRLHELMQNDREFSKEDRELINPCNSKSITQALDFVKNPVDCCHHVHLLIRELLHIISIKKDDPKTKDAILYHGETWDLMRCRWEKIEKDFSTKSKLFDISKIPDIYDCIKYDLQHNQHTLQYDQAEELYIYAKNLADIVIPQEYGLTPQEKLAIGQGICSPLLRKIKGDLQRNIDEVEDEFMNRLNPHYSHGVASPQRHVRTRLYFTSESHVHSLLTVLRYGGLLNVVTDEQWRRAMDYISMVSELNYMSQIVIMLYEDPTKDPTSEERFHVELHFSPGVNCCVQKNLPPGPGFRPHSHGDNACNVSLQSSDESNPARIEEENDSNSGEEREGKKRGTSGQRSTDRSAERISPAFGFNRLELRSKQFKSKPIPIGAHHTVSGHEAMDLAKRLNEELASHQQQQNQQLRPISPDIRAVTPDCEPRSRSFEQRPTSGVCAKEPDSQVSVSVSASVSSANASTSSRRQRHSIAGQMSYMKMLGFGGFSKKMATSANSLFSTAVISGSSSAPNLRDMITVSSSGFGDVPPIRPLETLHNALSLRKLDSFLQDMILAQIFKTPTGSPPRGFSKNTLPAVSSMTLTASNQTEVVEHEPISTTVTPTFDRRGSESGSTADAHLRLLSESQCPNLDDSNTELRESLAGKMELWPQDIVKAAEDEELNLSELETKPSLDLTMEIMERGVAGIASIQPMNRDSDETMGGGVFLSVCEEQGSGSTCLTPVSFGMDLDLSMVANKGSITLSMEGFDDDEDATLSAATTPSLLADCEPRLESCYCCPSHAEAPPEVPSDDPRFGFALPVRVTQASPEHARPVRRAHDPVSPRIQKQISLFEGNAAMATGQEKTESSGSVGGGAILHASINLPAAGPHHLRQDARLRKFENLTQSTSNSNFPFESNTLKRVPMQTTKDYDNVSHTQSCINLKSGSSGVLGGSPQRQRGSDGGGVGASGVPAESREPTRVHYGRMNSTCCSASASPSPSPGALIVKERFIEPPKRGVVRGYHGKTQSMDADFLFNEFLLLPAMAPAKISFDSSDIDQASDDDSPSSSKQRHA
What is the function of this protein?
Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4.  PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis.  Phosphorylates inositol hexakisphosphate (InsP6) at position 1 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4.  Alternatively, phosphorylates PP-InsP5 at position 1, produced by IP6Ks from InsP6, to produce (PP)2-InsP4.
What are the official names of this protein?
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase, InsP6 and PP-IP5 kinase.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family. VIP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TBB_EUPFO
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGVDPTGTYHGDSDLQLERINVYFNEATGRKICPRAMLMDLEPGTMDSVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKIREKYPDRIMETFSVFPSPKVSDTVVEPYNATLSVHQLVENADEVMCIDNEALYDICFRTLKPTTPTYGDLNHLVSAVISGVTSCLRFPGQLNSDLRKLAVNLIPFPRLHFFMIGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMCASDPRHGRYLTASAMFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNIKSSVCDIPPKGLKMSSTFIGNSTAIQEMFKRVAEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFDDEEEMDV
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: IF4E1_CAPAN
Sequence: MATAEMEKTTTFDEAEKVKLNANEADDEVEEGEIVEETDDTTSYLSKEIATKHPLEHSWTFWFDNPVAKSKQAAWGSSLRNVYTFSTVEDFWGAYNNIHHPSKLVVGADLHCFKHKIEPKWEDPVCANGGTWKMSFSKGKSDTSWLYTLLAMIGHQFDHEDEICGAVVSVRGKGEKISLWTKNAANETAQVSIGKQWKQFLDYSDSVGFIFHDDAKRLDRNAKNRYTV
What is the function of this protein?
(Microbial infection) Susceptibility host factor required for viral infection (e. g.  potato virus Y (PVY) and tobacco etch virus (TEV)) by recruiting viral RNAs to the host ribosomal complex via an interaction with viral genome-linked protein (VPg).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-1, eIF4E-1, eIF-4F 25 kDa subunit, eIF-4F p26 subunit, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NEJ1_YEAST
Sequence: MDSELKGQQLSDAEWCVKKINGEGNCLLLFLPMSSPTTIVMIVLVSLERLVPYVFKLSQTQLSQQCQSQGFTDSISLNLIKLKLMDILQAPQEINQIGLVDSNLVFSFDVSADITVSINSVPSHVTKDMFYMILQSLCMLLLKLVNLSTQYHYVQRDILNEKQKCLDFLLISLRDLDGGSKVISQWAPENSKNYESLQQCTDDDIIKKLLHKGKFQHQEFLADSLKTLLSLRNKFQDVSRFEESGELNKKERVRFPAVNHFYNDDFELQADPTNEARPNSRGKIKPKTDFKPKSRESSTSSQLRLENFSESEATPEKTKSSSSLVEEYPQKKRKFGKVRIKN
What is the function of this protein?
Involved in non-homologous end joining (NHEJ).  Facilitates the transport of LIF1 into the nucleus, where it can interact with DNA ligase DNL4 to repair double-strand breaks (DSB).  Mediates mating-type regulation of NHEJ.  Prevents chromosome circularisation by NHEJ in absence of telomerase.
What are the official names of this protein?
Non-homologous end-joining protein 1.
What is the protein family that this protein belongs to?
Belongs to the XRCC4-XLF family. XLF subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus membrane; Multi-pass membrane protein.
Protein: MARC_ECO57
Sequence: MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNGAERNRQSLMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAPPLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTNH
What are the official names of this protein?
UPF0056 inner membrane protein MarC.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMD_PSYWF
Sequence: MYFAVITILPEMFTAISEYGITGRAVQNKQVVIDCINPRDFTTDNYRRIDERPFGGGPGMVMMAEPLAKAIAYAKSQASLHGCITDSEHCPVVYLSPQGDKLDEAAVVSMRHYEAMILLCGRYEGIDERLLARYVDMEISIGDFVLTGGELPAMVLMDSVIRRLPDVMGDAKSAEQDSFVEGLLDCPHYTKPHDFEGLQVPEVLLSGHHANIATWRFMQQVERTKQRRPDLWQSFTPNAEQARLLKKVNKTMK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_CLOP1
Sequence: MVKVILNGCSGKMGSVISNLAETKFPNVEIVAGIDNNTKAQRPYPIFAKPEDCNVSYDVLLDFSRADALKSLVEFSKKTKKPLILCSTGYTAEDLKFIEESSKEIPLFRSANMSIGINLVNNLLKKVAPVLYENFDIELVERHHNQKVDAPSGTALLLAHTIQDSLKEETKLLYGREGIAKREKNEICVNTVRGGGIIGDHEVIFAGDGEVIEINHKAISRDVFAIGALKACEYMADKTKAGKYSMDDVLQLNF
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_PROM4
Sequence: MNKQFHSCSPDPDDGEKLDIDYLSDEGPSTLIFEPSELIDFRVAWDWQKQRQKLLFEKPGSSQAVWLLEHSECYTLGRGATEDNLLFNLSNSPWDVYRIDRGGEVTHHMPGQLVVYLVLDLRRYKTDLNWYLRQLELVLLDTLKDLGIVGKRIDGITGVWINDFKVASIGVGCRRWITQHGLSINVDCDLRGFERIIPCGLTGSKVGKLSSLIPDLKTVDVKPFIKKSLTERFGL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_STAAS
Sequence: MTNYKIDFSKGLVPAILQDNQTKQVLMLGYMNQEAFDKTIEDGVVCFYSRSKQRLWTKGETSGHTQRVKDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTEVPFSVQTLAQTVQDSAQSNNEKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKAFVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPG_BUCAI
Sequence: MANILLLDNIDSFTYNLVEQLRNQKNNVLVYRNTVSIDIIFNSLKKLTHPILMLSPGPSLPKHAGCMLDLIKKVKGDIPIVGICLGHQAIVEAYGGIIGYAGEIFHGKASLIRHDGLEMFEGVPQPLPVARYHSLICNKIPEKFVINSYFEKMIMSVRNNCDRVCGFQFHPESILTTHGDQILEKIIHWASLKYITNKKQ
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 2, AS, ASII, Anthranilate synthase, GATase component, Anthranilate synthase, glutamine amidotransferase component.
Protein: PUR6_CRYNH
Sequence: MAPRKTVGILGGGQLGRMLTHPAALLGIPLLILDSGSFTPAKQTLLPPPSHSHPDGPFTSEPHIRKLASACDILTVEIEHVNADVLEAVEKEGLCEVQPSPKTIRLIQNKYDQKKYLAEKGVAVAPFEELPANPTEEDFKAIAGRLGLPLMLKAKTLAYDGRGNSPLKSTSSEDIQASLKFLGDRPLYAEGWAPFVKEVAVMVVRNKEGEVQSYDAVETIHRESILRVCLAPLRGERGVNQRARELAEKAVGHLEGAGIFGVEMFLMPDGELLLNEIAPRPHNSGHHTIEACLTSQFENHLRAILSLPLGSTALRVPSAAMVNILGASSTMDAIDKMADNALTVPGAAVHLYGKAESRKARKMGHITVTAESDAELNERLRTLLFAQPDAHADWIDLIAPPSPAPAHSHPKPLVGIIMGSDSDLPVMHPATKILEKFGVPYELTITSAHRTPERMVKYAKTAAGRGLRAIIAGAGGAAHLPGMVASETSLPVIGVPVKASVLDGVDSLYSIVQMPRGIPCATVGINNSTNAALLAIRILGTSVPALNKATEEYSKALEEEVLAKVDILEEEGWDKYIERLKK
What are the official names of this protein?
Phosphoribosylaminoimidazole carboxylase, AIR carboxylase, AIRC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.
Protein: YTFE_ECO7I
Sequence: MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARKELDVDVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVERVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEHDEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMEHISLENNVLFPRALAGE
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein YtfE.
What is the protein family that this protein belongs to?
Belongs to the RIC family. YtfE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_HELPH
Sequence: MNLINEKLDNLENNATKSPKEAVVLLNMGGPNSLYEVGVFLKNMFDDPFILTIKNNFMRKMVGKMIVNSRIEKSKKIYEKLGGKSPLTPITFALTERLNKLDPSRFYTYAMRYTPPYASMVLQDLALKEIESLVFFSMYPQYSSTTTLSSFNDAFNALKSLETFRPKVRVIERFYADKKLNEIILNTILNTLNNRKSQDFVLIFSVHGLPKSVIDAGDTYQQECEHHVSLLKELMQQKNIPFKEVLLSYQSKLGPMKWLEPSTEELIEKHRKSHIIIYPLAFTIDNSETLYELDMQYRLMAERLAIKEYLVCPCLNDSIEFAKFIIGLVKNLKSE
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP_TPCTV
Sequence: MATTNCRICGSSFACPINERFSVCESRGATLSDFLLYFRRKYIETSPGLISYLNALQAEINELFSAIKEVSRSEIRHGSCEDKCQPSSIQKGKAEA
What is the function of this protein?
May be involved in the viral transport within, and between cells.
What are the official names of this protein?
Putative movement protein, MP.
Protein: RS19_PIG
Sequence: MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAXHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAG
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for pre-rRNA processing and maturation of 40S ribosomal subunits.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
40S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
Protein: FMT_BURL3
Sequence: MTHTLRVVFAGTPEFAAAALAAIHEAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHGMPVAQPPSLRRAGKYPAEAADAIELLRSTPHDVMVVAAYGLLLPQEVLDIPRDGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDIGLDTGAMIEEARIAIAPDETTATLHDRLAAEGARLIVDALVQLERDGVLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAFDPFPGGVATLDGAAIKLWAAEPVAARGEAAPGTIVEAAPEGVVVACGSGALRVTQLQKPGGKRLPAREFLAGSPLAAGQRFALTDVA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: ASSY_BACAH
Sequence: MEKKKVVLAYSGGLDTSVAIKWLQEKNYDIIALCLDLGEGKDLAFVKEKALSVGAIKSYMIDVQEEFANEYALMAMQAHTLYEGKYPLVSALSRPLIAKKLVEIAEQEGATAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKENNVPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTLALEDTPNKPEFVEIGFEAGVPTTLNGTAYPLSELIKTLNALAGKHGVGRIDHVENRLVGIKSREVYECPAAMTLITAHKELEDLTLVKEVAHFKPMIEQKITELIYNGLWFSPLKQALNAFLQETQKNVTGTVRVKLFKGHAIVEGRKSEYSLYDEKLATYTAQDEFNHDAAVGFISLFGLPTKVYSQVNQKKVEA
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BKRB1_MACMU
Sequence: MASWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICSFGLLGNLFVLLVFLLPRRRLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGIIKANLFISIFLVVAISQDRYCVLVHPMASRRRQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILAFLLPLAAIIFFNYHILASLRGREEVSRTRCGGSKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFLAFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
What is the function of this protein?
This is a receptor for bradykinin.  Could be a factor in chronic pain and inflammation.
What are the official names of this protein?
B1 bradykinin receptor, B1R, BK-1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL21_ECO7I
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PRDA_ACESD
Sequence: MSITLESAKEHANDLAVLCCRAEEGTVIGPSNLEDPAIFGDLEDSGLLTIPANCLKIGEVLGAKLVKTADSLTPLTPELLEGVNSISEEAPKQEASAPVEAPVAEVAPAAMPVANVTGSMLKIHIGEGKDINLEIPLTIAGQMGVVAPTAAAPAGVAMPVASATEQVVAPAGEPKLVRTLQKKHFKIEKVEFGPETKIENNTIYIRENICEDAVKVSNLVTDIKVEIITPADYGKYSETIMDVQPIATKEGDGKIGQGVTRVIDGAIIMVTGTDEDGVQIGEFGSSEGELDANIMWGRPGAPDKGEILIKTQVTIKAGTNMERPGPLAAHKATDFITQEIREALKKLDDSEVVETEELAQYRRPGKKKVVIIKEIMGQGAMHDNLILPVEPVGVIGAKPNVDLGNVPVVLSPLEVLDGGIHALTCIGPASKENSRHYWREPLVIEVMNDEEFDLAGVVFVGSPQVNAEKFYVSERLGMLVETMDVEGAFITTEGFGNNHIDFASHHEQVGMRGIPVVGMSFCAVQGALVVGNKYMKYMVDNNKSEQGIENEILSNNTLCPEDAIRAVAMLKAAIAEEEVKVAERKFNKNVKENNVDLIEEQAGKEITLLPNEQVLPMSKKRKEIYEADK
What is the function of this protein?
D-proline reductase catalyzes the reductive cleavage of a C-N bond in D-proline resulting in the formation of 5-aminovalerate.  The alpha subunit has been shown to bind D-proline, presumably via the pyruvoyl group.
What are the official names of this protein?
D-proline reductase proprotein PrdA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYBT_DICDI
Sequence: MFEINGNLKVDINKFKKIYTTVFDKNISPQINEILDLFEFDTTKSSYEDVIEEYSKFENDSLGSFEYLDYSDLRLLSKRKWNNKEALIIGNGKSNYKTTVQIKGDLLDKVLKKPSPVISRNWSPDEQKALMVEVSTLGNKSEINWFFISQQLFLKGISRNARECQRKHESIQYVGLSGNPKAKFKGTFD
What are the official names of this protein?
Myb-like protein T.
Protein: CCL22_HUMAN
Sequence: MDRLQTALLVVLVLLAVALQATEAGPYGANMEDSVCCRDYVRYRLPLRVVKHFYWTSDSCPRPGVVLLTFRDKEICADPRVPWVKMILNKLSQ
What is the function of this protein?
May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology.  Chemotactic for monocytes, dendritic cells and natural killer cells.  Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes.  Binds to CCR4.  Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
What are the official names of this protein?
C-C motif chemokine 22, CC chemokine STCP-1, MDC(1-69), Macrophage-derived chemokine, Small-inducible cytokine A22, Stimulated T-cell chemotactic protein 1.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PG072_VAR67
Sequence: MNPKHWGRAAWTIIFIVLSQAGLDGNIEACKRKLYTIVSTLPCPACRRHATIAIEDNNIMSSNDLNYIYYFFIRLFNNLASDPKYAIDVSKVKPL
What is the function of this protein?
FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation.  The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves thiol-disulfide transfer between OPG072, OPG128 and OPG088.
What are the official names of this protein?
Probable FAD-linked sulfhydryl oxidase OPG072, Probable FAD-linked sulfhydryl oxidase E10.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG072 family.
Protein: YBDG_ECOLI
Sequence: MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIILHWVVLRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTCAQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLLIGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGAVIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRFLDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEYLRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEEFGLRLHQSPTGNDIRSLAGAFKQ
What is the function of this protein?
Mechanosensitive channel of miniconductance that confers protection against mild hypoosmotic shock.  Overexpression confers protection against severe shocks.
What are the official names of this protein?
Miniconductance mechanosensitive channel YbdG.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HPRT_ECOLI
Sequence: MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLDE
What is the function of this protein?
Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate).  To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.
What are the official names of this protein?
Hypoxanthine phosphoribosyltransferase, HPRT, 6-oxopurine phosphoribosyltransferase, 6-oxopurine PRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_CAMC1
Sequence: MKDKVKAEISKVLEREFVLEKPKDKNLAHYATPLFSLAKELRKSPAMIASEFADKFSDSKIVEASAVNGYLNFKLKSEFLDEISKQILLDSENFAKEDAKKDSYLIEYISANPTGPLHIGHVRGAVYGDTLARLGKRLGYAISTEYYINDAGNQIDLLGTSISLAAKEQLFNESVVYPEKYYRGDYILDIAKLANEKFGKEIFYDESRNLELAEFGKDIVLEIIKKDLADVGIFIESWASEKALYDGLEPTINKLKRSNQMYEKEGATYIASTTLGDDNDRVVVRNDGRPTYLAGDIIYHNAKFEKNFDHYINIWGADHHGYIARLKAAINFLGYDENRLEVILMQMVSLLKEGKPYKMSKRAGNAVLMSDIASEIGAEALRFIFISKANTSSLEFDVDELKKEDSSNPIFYINYAHARINQIFAKAGKSVSDVINADFECLDENSKNLLFEALILPEILEDAFASRQLQKIPDYLKSLAASFHKFYNENRVVGNENEDSLLKVFAVVAVSIKTAFNIMGITAKDRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.