PharMolix/UniProtQA huggingface dataset:
Protein: EFG_MYCTO
Sequence: MAQKDVLTDLSRVRNFGIMAHIDAGKTTTTERILYYTGINYKIGEVHDGAATMDWMEQEQERGITITSAATTTFWKDNQLNIIDTPGHVDFTVEVERNLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYDVPRICFVNKMDKIGADFYFSVRTMGERLGANAVPIQLPVGAEADFEGVVDLVEMNAKVWRGETKLGETYDTVEIPADLAEQAEEYRTKLLEVVAESDEHLLEKYLGGEELTVDEIKGAIRKLTIASEIYPVLCGSAFKNKGVQPMLDAVVDYLPSPLDVPPAIGHAPAKEDEEVVRKATTDEPFAALAFKIATHPFFGKLTYIRVYSGTVESGSQVINATKGKKERLGKLFQMHSNKENPVDRASAGHIYAVIGLKDTTTGDTLSDPNQQIVLESMTFPDPVIEVAIEPKTKSDQEKLSLSIQKLAEEDPTFKVHLDSETGQTVIGGMGELHLDILVDRMRREFKVEANVGKPQVAYKETIKRLVQNVEYTHKKQTGGSGQFAKVIINLEPFTGEEGATYEFESKVTGGRIPREYIPSVDAGAQDAMQYGVLAGYPLVNLKVTLLDGAYHEVDSSEMAFKIAGSQVLKKAAALAQPVILEPIMAVEVTTPEDYMGDVIGDLNSRRGQIQAMEERAGARVVRAHVPLSEMFGYVGDLRSKTQGRANYSMVFDSYSEVPANVSKEIIAKATGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_CERSI
Sequence: MVLSPTDKTNVKTAWGHVGAQAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKAHGKKVGDALTQAVGHLDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLALHHPQDFTPAVHASLDKFLSNVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RPOZ_PSET1
Sequence: MARVTVEDAVDAIGNRFDLILVAARRARQIAVGGKRPLVDPENDKPTVIALREIELGLVDSSSMDVIDREEQQHQEAAELAAVAAIVGGNQ
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: CUTC_VIBC1
Sequence: MNTQLEVCIDNIESLHNAIAGGPTRIELCSSLALGGLTPSYGFMQQAAKHSTIPVYAMIRPRQGDFFYSEEEIELMRWDIEAAKQAGLNGVVLGVLTQDGNIHMPYATALCEFAQALGLGVTFHRAFDQCRDAEKALEEVISLGCERILTSGLAPSAPQGIDVLKALVEQAQGRIALMAGAGVNADNVGQIVEQTKVTEVHLSGKTTRPSHMTFIAEQSKMGAADVDDFSIPVTNTDAIANMVTALN
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP32_YEAST
Sequence: MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNGAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS
What is the function of this protein?
Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step.  May play a role in detoxifying endogenously produced glyoxals.  Involved in protection against reactive oxygen species (ROS) (By similarity).  Important for viability in stationary phase.  May negatively regulate TORC1 in response to nutrient limitation (PubMed:24706893).
What are the official names of this protein?
Probable glutathione-independent glyoxalase HSP32, Glyoxalase 3 homolog 2, Heat shock protein 32.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HSP31-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Present in processing bodies (P-bodies) and stress granule (SG) foci upon glucose starvation and heat shock.
Protein: CAPA_STAAU
Sequence: MESTIDLSELLGRVRKNMKLLIILPLLGLLISAIISFFFLDVKYQASTQILVNQKGNDSQIMAQEVQSNIQLVNTYSEIVKSPRILDKVSKELDDKYSRSEISSMLTVTNQAESQVLNIDVESKSGSNSEKIANKIAEVFSDEVPDIMNVDNVSVLSTADNTGKQVAPKPMVNLVVGLVIGLVIALLIIFIKEVFDKRIKTEEEVENELVIPVLGSIQKFD
What is the function of this protein?
Required for the biosynthesis of type 1 capsular polysaccharide.
What are the official names of this protein?
Capsular polysaccharide biosynthesis protein CapA.
What is the protein family that this protein belongs to?
Belongs to the CpsC/CapA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NPL4_ASPFU
Sequence: MAAARPIILRFESRNGQFRLSVSPQEQFPFLKEKILENLPKDVEPSSLVLSNKPIGTGGQERQLKDLTGVSIERVGLKHGDKLFIGYQDKQASQAAPAQKHVTADVSRRLNGAPVPETETVAFHPPTSPSATIKNPWEVVQQSPLDDMLDKKDGKIYRPRDPKMCKHGPKGMCDYCMPLEPYDPKYLAEKKIKHLSFHSYMRKVNASTNKAELKSSFMPPLTEPYYRVRRDCPSGHPPWPEGICTKCQPSAISLQPQEFRMVDHVEFASPDLINSLLDFWRKSGAQRLGFLYGTYEEYTEVPLGIKAVVQAIYEPPQVDEIDGITLHEWPNEKEVDEVARQCGLEKVGVIFTDLLDAGRGDGSVVCKRHIDSYYLSSLEIAFASRMQAKHPKPTKWSRTGRFGSNFVTCVLSGDEEGAITVSSYQASISAVEMVRADIIEPSAEPSVMLVQSEDEDTDNKSRYIPEVFYRKINEYGVSAQQNAKPSFPVEYLLVTLTHGFPTEASPIFPASTFPIENREVIGESQELRHVAKKLVSHGDPDKAIREVSDFHLLCFLHSLSMFSKEEEALLCRVATTHDPTEGLKLLNTPGWATLVTVLQESGERPPKRPWLNPADPPRPLSQQGKRHLPSRPESPKSESEQLAKRFKGASLE
What is the function of this protein?
Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus.  Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).
What are the official names of this protein?
Nuclear protein localization protein 4.
What is the protein family that this protein belongs to?
Belongs to the NPL4 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes mainly at the nuclear periphery and the endoplasmic reticulum membrane.
Protein: GLT10_DROME
Sequence: MNVDLRLIVRLLLAILLTSLVTTILMGKQIHRRLVKSMVKTTGEKDSLPARQLPKREISPKVADFPPPLTLNQTELDILKIQRNNSFRLPQQEAIKEWQDAIFFKEDSNRRGLGEQGRAVQLPNAKLNPDDFQDFYAELSDRIPLNRSLPDTRPISCRKRKYLENLPNVTVIIAFHDEHLSVLLRSITSIINRSPVELLKQIVLVDDDSNLPELGQQLEEIVAQNFPKIIHILRLPERRGSIKARMEAIRVSSCQVLVFLDSHIEVNTNWLPPLLEPIVINPHIVTRPILDAISRKTFAYAKQNTMTRSGFNWWLESESLPIFPEDKSPDSTPYRTPVLSGAMAIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGGMMLYVPCARVGHIGKRPMKSISSPGYHNFLARNYKRVAEVWMDNYKKYVYDKNPKLYKMANAGLLFQRKTKRNALECKTFDWYMTKVAPDFLKRYLALDSPLVFSGVIESVAFPGFCVDSLNCRHTKPVVLARCTGHNSMPGEHQNWSLTQDHEIQLTNSKDDCLEAQGLRSKSVWLFRCHKNGGNQYWYYNHRHRWIQQGQIWVWCLEAQLASGHKVGKVLANKICDKNQLEQQWKVGRNAPYDPQREPH
What is the function of this protein?
May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
What are the official names of this protein?
Putative polypeptide N-acetylgalactosaminyltransferase 10, pp-GaNTase 10, Protein-UDP acetylgalactosaminyltransferase 10, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: CHEB_SHIFL
Sequence: MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAIDFVTKPQLGIREGMLAYSEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGERVLPGHAYIAPGDRHMELARSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAVGVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVSQQMLATISAGQAIRI
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25A_SCHPO
Sequence: MSVAKAKGAQKTVQKGIHNKVAKKVRTSTTFRRPKTLQLSRKPKYARKSVAHAPRLDEYKIIVNPINSESAMKKIEDDNTLVFHVHLKANKFTIKEAVRKLYSVEPVKINTLIRPNGTKKAFVKLSADADALDVANRIGFL
What is the function of this protein?
This protein binds to a specific region on the 26S rRNA.
What are the official names of this protein?
60S ribosomal protein L25-A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: THN5_WHEAT
Sequence: MGGGQKGLESAIVCLLVLGLVLEQVQVEGVDCGANPFKVACFNSCLLGPSTVFQCADFCACRLPAGLASVRSSDEPNAIEYCSLGCRSSVCDNMINTADNSTEEMKLYVKRCGVACDSFCKGDTLLASLDD
What is the function of this protein?
Thionins are small plant proteins which are toxic to animal cells.  They seem to exert their toxic effect at the level of the cell membrane.  Their precise function is not known.
What are the official names of this protein?
Type-5 thionin.
What is the protein family that this protein belongs to?
Belongs to the plant thionin (TC 1.C.44) family.
What are the subcellular locations of this protein?
Secreted.
Protein: VIP_PIG
Sequence: HADGVFTSDFSRLLGQLSAKKYLESLIXXXXXXXXXXXXXXXXXHSDAVFTDNYTRLRKQMAVKKYLNSILNGKR
What is the function of this protein?
PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin (By similarity).  PHI also causes vasodilation.
What are the official names of this protein?
VIP peptides.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: RDRP_AQRVG
Sequence: MEDLFNALPQPLQQLSLALAGEIPLNDELFQAAASTWHTRQRSETYHLLDRLRFSTPIVTPQAIYRDLPWRNCYRINQDRVERIPTTNASDDVYVPNSDISTLLSPLFSIPTYGTLHPSIEKDALELRADSARCASTFYKIASSQARQVKLDPTRMLEFLLLLVATPRVNSGLDTDQPSMRDPTKSPALHAIWQIMQYYKVDSKYHAPALIVSTGAVWWIPPPGKRNVVSVQYLLTDLVNLAIIARMTDMHPTLGLCAARVYIQAATTDSYTHTLLKLKGVFPALSIHSMYRQKGFGGKAPDIQWTEPRTKYQFKWVGVTHLHDGLRPRAPVRDEAVRKLLTEYQLADIMAPIVEMRNQHKHHDHDSVRFVRDVMALTSGMYLVRQPTMSVLQEYSQVPDIKQPIPPSAWTGTVGNVRYLNKDVTGPARWLYNTWREAAQEIAQDRTWHDPVNQFIMGSQYVTARGGSGSSLKHSLTVTGLVLPEFSESSVKRSSKIYQAAQIARIPFTLLTAAIHAEVVMAIRNQVQRRARSIMPLNVVQQAVSAPHTLVANYINKHMNMSTTSGSVVTDKVVPLLLYASTPPRTVVNVDIKACDASITYDYFLSLICGAMHEGFEVGDNHASFMGVPSSIIMDKRSALAPYSRTVSGLQTMVQHLSQMYANGFRYSVTDAFSSGNKFSFPTSTFPSGSTATSTEHTANNSTMMSYFLAVHAPQHIKSPNMKRVLSDMTIQRNYVCQGDDGVLLLPDEAASKISAEDMDELLTCLKDYGTSFGWVYDIDWSDSAEYLKLFALCGCRVPNVSRHPPVGKEYASPTTDEIWPSLIDIVVGHHLNGVMDLMNWREWLRFSWAFACYASRGAYTDKYGETHIAQYPWWTFVYLGIPPILLPGQTPFIHSLFMPPGDQAMFAILNNWRDLISTNTTTTFPPLKHPHHTWHLADVPTLLDSYGVYAGYHAAQHPRRPVAQPETANSESIEQITGALTDYLLYDPILKARVNTGRHNWSQLSQSIGLNIGGRVPSLMDVPGKWVAAGREAEKPPPSAIVYMFKSLNRTIRRPSKHFSKLLELYIRVKVVLGAPKPLAIDPDIPQVAGADPHNDDPWFKYVGLGDIPTSTRRYFGESLFVGRVVSGLDVEAVDAALLRLKILGAPPAAYIALLNGIGMSNSEANQIAGRVSLANAQTVQIGRVVNLSTPSSWMTLDTAPYIQYHTYDFKPGVTNPSAQSREKFIWLSPILKLLCATAAMSIAGPVREAYVLDIHGSAASLSGNFREWMRAA
What is the function of this protein?
RNA-directed RNA polymerase that is involved in transcription and genome replication.  Following infection, it catalyzes the synthesis of fully conservative plus strands.  After core assembly, which consists in recruitment of one capped plus-strand for each genomic segments and polymerase complexes, the polymerase switches mode and catalyzes the synthesis of complementary minus-strands (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase VP2.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion.
Protein: YR710_MIMIV
Sequence: MSWHTGSNQDNKLFPKGKLSGSYAPLDIAFENSPAMNEFENRLCHNNPIISERSMSPAVSASYSNPEATSCGCMQTQTQPQHQTLSQHLPQTHHTDAHDQQKLSGIFYNRTTDAQNQFSETINPPPSYTVHNTDIRIPLNRQQQYPANHLGSELLEGYNNVGTEPCMGFWEILLLIILIAVLVYGIYWLYKSEK
What are the official names of this protein?
Uncharacterized protein R710.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: MTAP_LEPIC
Sequence: MSYNVRVAIIGGTGLYSLEGMELIEEIFPDTPWGKPSDKIKIGKYKGKLIAFLPRHGIGHFLSPPEVPNHANICALKQLGVEEIVAFSSVGSLREEIKPLDFVLPSQIIDRTRFRNSTYFGNGVVAHAPFAEPFSPNLSKRIAQTAKKIGLEIHLDKTLVCMEGPLFSTKAESHLYRSWGADIINMTVLPEAKLAREAEIAYQMICMSTDYDCWREGEESVTVEMVIANLTKNAETAKKLLSELIHVLGNGDDLSLKNSTRYSIITAPEKRNPETVKKLRVLFPEYF
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: CARB_SULIM
Sequence: MKETPKKVLVIGSGPIKIAEAAEFDYSGSQALKALKEEGIETVLVNSNVATVQTSKKFADKLYMLPVVWWAVEKVIEKERPDGIMIGFGGQTALNVGVDLHKKGVLQKYGVKVLGTQIDGIEKALSREKFRETMIENNLPVPPSLSARSEEEAIKNAKIVGYPVMVRVSFNLGGRGSMVAWTEEDLKKNIRRALSQSYIGEVLIEKYLYHWIELEYEVMRDKKGNSAVIACIENLDPMGVHTGESTVVAPCQTLDNLEYQNMRTYTIEVARSINLIGECNVQFALNPRGYEYYIIETNPRMSRSSALASKATGYPLAYVSAKLALGYELHEVINKVSGRTCACFEPSLDYIVTKIPRWDLSKFENVDQSLATEMMSVGEVMSIGRSFEESLQKAVRMLDIGEPGVVGGKIYEAKMSKVEALKYLKERRPYWFLYVAKAFKEGATIDEVYEVTGISKFFLNKIKGLVDFYETLKILKEIDEETLKLAKKLGFSDEQISKALNKSTEYVRKIRDQSNIIPVVKLIDTLAGEWPSVTNYMYLTYNGTEDDLEFSQGNKLLIVGAGGFRIGVSVEFDWSVVSLMEAASKYFDEVAVLNYNPETVSTDWDIARKLYFDEINVERVLDLIKKEKFRYVATFSGGQIGNSIAKELEENGVRLLGTSGSSVDIAENREKFSKLLDKLGISQPNWVSATSLEEIKKFVNEVGFPVLVRPSYVLSGSSMKIAYSEEELYEYVRRATEISPKYPVVISKYIENAIEAEVDGVSDGNRVLGITLEHVEEAGVHSGDATMSIPFRKLSENSVNKMRENVLSLARELNIKGPFNVQFVVKDNTPHIIELNLRASRSMPFSSKAKGINLINESMKAIFNGLDFSEDYYEPPSKYWAVKSPQFSWSQLRGTYPFLGPEMKSTGEAASFGVTFYDALLKSWLSSIPNRIPNKNGIALVYGDKNLDYLKDTAVNLVKFGLTVYSISELPLQGIETIDKTKAEELVRAKKVEIVVTDGYLKKFDYNIRRTAVDYNIPVILNGRLGYEVSKAFLDYDSLTFFEISEYGGGI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: AB25B_ORYSJ
Sequence: MGKNLRIKTGNRAPLLAQGETSRALSDLEEGSNVQPENVGFCRVIKLARHDAGKLVIATMALLVASLSNILVPKYGGKIIDIVSRDVRRPEDKAQALDDVTGTILYIVIIVVTGSVCTALRAWLFNSASERVVARLRKDLFSHLVNQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNITTTSIGLGFMFATSWKLTLLALVIVPVISIAVRKFGRFLRELSHQTQAAAAVASSIAEESFGAIRTVRSFAQESHEVLRYGEKVDETLKLGLKQAKVVGMFSGGLNAASTLSVVIVVIYGANLTINGYMTTGSLTSFILYSLTVGSSVSALSGLYTTVMKASGASRRVFQLLDRVSSMANSGDRCPTNENDGEVELDDVWFAYPSRPSHMILKGITLKLTPGSKVALVGPSGGGKTTIANLIERFYDPLKGRILLNGVPLPEISHQFLHRKVSIVSQEPVLFNCSIEENIAYGLEGKASSADVENAAKMANAHNFICSFPDQYKTVVGERGIRLSGGQKQRVAIARALLMNPRVLLLDEATSALDAESEYLVQDAMDSLMKGRTVLVIAHRLSTVKSADTVAVISDGQIVESGTHDELLSRDGIYTALVKRQLQGPRFEGTSNATAEIEPISNGQ
What is the function of this protein?
Metal transporter involved in the sequestration of aluminum into vacuoles, which is required for cellular detoxification of aluminum.
What are the official names of this protein?
ABC transporter B family member 25, ABC transporter ABCB.25, OsABCB25, Protein ALS1 homolog, Protein ALUMINUM SENSITIVE 1, OsALS1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: Y3202_DICDI
Sequence: MDVNIFHFLFTKTNPGENFSCPKCKILIYDFDKVSEVYQCKNGSWACKNCWIEIFRTTKECPTKECRVESIDSLSRSRFIENGFAGKNMDCPNSLVRSNPNHYEGINVLLDDDGCRDVVTVGNLSSHLKGCIYAFTKCPNDVNGCTGEFRLKNLDQHLQTCGFQLEDCPNCNNKIIRKSIEEHIDEECLKTKIKCLECGSTVERGDMDFHLDNVCPNIVIPCILCDNGCDLLFKRSELSNHLQSIEHISNLNNKIDELNETLNDLQISELNQKVEQLETLLTQARDDPLAQREINRLISKQEKFKSVWDIKNFSKRQFQKGFYFSSPVITVGHHSFHLWLYPNGETSPSNSLSLYLVLTKGEKTFVNFSISIKNHNGNDLNSTFENDKCLEVGGTRWGWAFEKDFKTGGYLKNDTLSIQFTVAIKKQPLITDILSVQ
What is the function of this protein?
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
What are the official names of this protein?
TNF receptor-associated factor family protein DDB_G0293202.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX6C_VICPA
Sequence: MSSGALLPKPQMRGLLAKRLRVHIVGAFVVALGVAAAYKFGVAEPRKKAYADFYRNYDSMKDFEEMRQAGVFQSAK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6C, Cytochrome c oxidase polypeptide VIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6c family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: YEIH_SALTI
Sequence: MTELTLQNHRRTMWHFIPGLALSAVITGVALWGGAIPAVAGAGFSALTLAILLGMVIGNTVYPQIWKQCDGGVLFAKQHLLRLGIILYGFRLTFSQIADVGISGIVIDVLTLSSTFMLACFLGQKVFGLDRHTSWLIGAGSSICGAAAVLATEPVVKAEASKVTVAVATVVIFGTIAIFLYPAMYPLLAHWFSPETYGIYIGSTMHEVAQVVAAGHAVSPDAENAAVIAKMLRVMMLAPFLIILAARVKQLSPATGAEKSKITIPWFAIFFIVVAIFNSFHLLPKAVVDMLVTLDTVLLAMAMAALGLTTHVSALKKAGAKPLLMALALFAWLIIGGGAINVLIHSLIA
What are the official names of this protein?
UPF0324 inner membrane protein YeiH.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEU1_BUCUN
Sequence: DGEQALQASLSVKEKLQIALCLEKAGVDIMEVGFPISSPGDFKSVQTISQNIKNSRICSLARCIEKDIDTAGEAMSHCDFFRIHVFLATSTLHMESKLRKNFDEIIDMAIFSVKRALRYTDDVEFSCEDASRTTMDNLCRIVEKLISCGVKTINIPDTVGYTIPNELSLIIKNLFERVPNIHKSTISVHCHNDLGMAVGNSISAIQAGARQIEGTINGIGERAGNTALEEVIMAIKVREDILGLSTNINHKEIYRTSQVISRICNMPIPSNKAIVGSNAFSHSSGIHQDGVLKNRENYEIMDPSSIGLKKVKLNLTSRSGRAAVKYYMNEMGYKDSDYNIDELYVDFLKLADKKGQVFDYDLEALAFINKKQDELEHFCLKFFSVQSISNNLSTASVTLLCGDKIYTESSTTSNGPVXAIYQALNRITHFPIILQKFQLIAKGQGKDALGQVDILVKYKKRQFHGVGLATDIIESSAQAMINVLNNIWKVKQVNKNLKNLKK
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: Y1337_RICCN
Sequence: MVNFNQFLKQAQSMQKKMQEAQEQMANARYTGKAGGGLVEVIATGKGEVEKISIDESLLKAEEKEMLEDLIKVAFNDAQQKCDEDSQNSLSGALNGMRLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein RC1337.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS2_RHORT
Sequence: MALPTFSMRQLIEAGCHFGHNTRRWNPKMAPYLYGQRDNVHIIDLQQTVPMLYRAMQAVRDVTAGGGRVLFVGTKRQAQDVVAEHARRCGQYYVNHRWLGGMLTNWKTISHSIKRLRDLEERFGGGDLLGLTKKEQLNLGREKDKLDMALGGIKEMGGLPDMLFIIDTVKESLAVNEANKLGLPVVAVIDSNSDPRGITYPIPGNDDAIRAIQTYCELISGAAIDGIQAQLGAAGVDVGAAEIVPAETLAAEAPAAEQQPTA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: DCPS_CAEEL
Sequence: MKRIADEELVREERAEESTQKWLQDAKFQEILGADSSHKSLFVLLSHPDGSQGILLANKSPFSEEKSDIEKLLATAQLQEISRNDIFGSYNIEIDPKLNLLKSQLIYPINDRLIAKYRQEEKFVIRETPELYETVTRPYIEKYQLNLNWVYNCLEKRSEVDKIVFEDPDNENGFVLLQDIKWDGKTLENLYVLAICHRHGLKSVRDLTGDDLEMLYNMRDKSLEAINQKYGLKTDQIKCYFHYQPSFYHLHVHFINLKYDAPASTTMSAILLDDVINNLELNPEHYKKSTLTFTRKNGDKLMEMFREALKN
What is the function of this protein?
Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs of the 3'->5' exosome-mediated mRNA decay pathway.  Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) and tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with up to 2 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP).  Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules.  Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) and tri-methylguanosine diphosphate (m3(2,2,7)GDP) to m(7)GMP and m3(2,2,7)GMP, respectively (PubMed:22985415).  May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by dcs-1 to m7GMP.  Binds to m7GpppG and strongly to m7GDP.
What are the official names of this protein?
m7GpppX diphosphatase, Decapping scavenger enzyme, Heat shock-like protein, Protein DCS-1, Scavenger mRNA-decapping enzyme DcpS.
What is the protein family that this protein belongs to?
Belongs to the HIT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMFO_STAAR
Sequence: MTQTVNVIGAGLAGSEAAYQLSERGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFSGYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEAAPVNSFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQFAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKNFQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.