PharMolix/UniProtQA huggingface dataset:
Protein: GUAA_SHISS
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWARLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: FMT_MYCTU
Sequence: MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPSPVAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLLAVPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGPIYGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPADGVSVAPKITVANARVRWDLPAAVVERRIRAVTPNPGAWTLIGDLRVKLGPVHLDAAHRPSKPLPPGGIHVERTSVWIGTGSEPVRLGQIQPPGKKLMNAADWARGARLDLAARAT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: CYML3_MELLF
Sequence: GKPICGETCFKGKCYTPGCTCSYPICKKD
What is the function of this protein?
Probably participates in a plant defense mechanism (Potential).  Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) (PubMed:26322745).  In vitro, displays cytotoxicity against cultured cells (PubMed:26322745).  Not active against Gram-negative bacterium E. coli ATCC 25922 or Gram-positive bacterium S. aureus ATCC 25923 up to a concentration of 64 uM (PubMed:26322745).
What are the official names of this protein?
Cyclotide mela-3.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebuis subfamily.
Protein: DF107_ARATH
Sequence: MAITMKTLIAYVFTVLLIISSVHCRMTTTTSPGFGIKQQDRQCFEHAPYLCRGGEGDCRMYCRDLDFSFGTCFSGVCCCQI
What are the official names of this protein?
Defensin-like protein 107.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3073_MYCTO
Sequence: MVRETRVRVARVYEDIDPDDGQRVLVDRIWPHGIRKDDQRVGIWCKDVAPSKELREWYHHQPERFDEFASRYQEELHDSAALAELRKLTGRSVVTPVTATRHVARSHAAVLAQLLNGR
What are the official names of this protein?
Uncharacterized protein MT3158.
What is the protein family that this protein belongs to?
To E.coli YeaO.
Protein: PDXA_SYNR3
Sequence: MTRLAIALGDPAGIGAEVVLKALAHRPSLNPLLVGCRQWLQASYEQLLPCCHEPLADPSQLEILDEPLTEAITPGSISAAAGAASFGWLTRATEAVLDGRAQALVTAPIAKTAWHQAGHHYPGQTERLAELCGCDDAAMLFTARSPQSGWRFNTLLATTHIPLSSVPAALTPERLERRLGQLEDFCRRFRQRPRLRVAGLNPHAGEAGQLGTEEQRWITACLQAYQQRHNNLQLEGPVPPDTCWLGAAQAWNDSQHVEEGCDGYLALYHDQGLIPVKVLAFDQAVNTTLGLPFLRTSPDHGTGFDRAGQGSARGASMLAAIDTAVELG
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIAA_ECOUT
Sequence: MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDV
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: RS21_VIBCH
Sequence: MPVVKVRENEPFDVALRRFKRSCEKAGILSEVRRREHYEKPTTVRKRAKAAAQKRHAKKLARENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ESTD_THEMA
Sequence: MRLTVFLSLFLGVMVFGAFDQEAFLFVQHLTSENFESALNMCSNQVKAQLSVQSLSNIWNSLKAQLSDFREIAGYEKIIQAEYEIYNFTLKFDRGEISALVTMDREGKVAGLFFKQATKTEYELPDYVDPESFEEKDITVNGLPGKITIPKGSGPFPAVVLVHGSGPNDMDETIGPNKIFKDIAYGLSSKGIIVLRYHKRTFVEKVDPTTLTVEKEVIEDALEAVKILKERKDVSRVYVLGHSLGAMLTPEIAERSKADGVVMIAPPARPLEEVMEDQLKYLQSLGLASNVEETLNILEKLKRKEIPPDEFVLGAPAKYFYDLRERDPASIAKRLTIPMLLIFGGRDYQVTEKDQEIWLKELSGRENVKILVFDDLNHLMISGEGKSTPVEYMKKGHVDKRVIDEIARWMVK
What is the function of this protein?
Exhibits significant esterase activity with a preference for short acyl chain esters (C4-C8) in vitro.  Its physiological function is not known.  Displays neither proteolytic activity using casein as substrate, nor peptidase activity when assayed with L-leucine p-nitroanilide and L-proline p-nitroanilide.
What are the official names of this protein?
Esterase EstD.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Esterase 10 family.
Protein: PLETY_LOTJA
Sequence: MIVRKNMGRAKSLLMLLMVLGFFFATYNLVSMIMDHRAGNWVADGLESFDRKMLGSASTNAKYHVALTATDAAYSQWQCRIMYYWYKKVKDMPGSNMGKFTRILHSGRTDQLMDEIPTFVVDPLPEGLDRGYIVLNRPWAFVQWLEKADIEEEYILMAEPDHIFVNPLPNLASRTQPAGYPFFYIKPAENEKIIRKFYPKDKGPVTDVDPIGNSPVIIQKSLIEEIAPTWVNVSLRMKDDPETDKAFGWVLEMYAYAVASALHGVKHILRKDFMLQPPWDRHVGKTFIIHYTYGCDYNLKGELTYGKIGEWRFDKRSYLMGPPPKNLSLPPPGVPESVVRLVKMVNEATANIPEWDSLNRS
What is the function of this protein?
Glycosyltransferase involved in the O-arabinosylation of several proteins including extensins and small signaling peptides (Probable).  Catalyzes the transfer of the initial L-arabinose to the hydroxyl group of Hyp residues (PubMed:30351431).  Probably involved in the arabinosylation of CLAVATA3/ESR-related (CLE) signaling peptides that move from root to shoot, to interact with receptor kinase signaling that regulates nodulation (PubMed:30351431).  Involved in long distance nodulation signaling events (PubMed:30351431).  Involved in the autoregulation of nodulation (AON), a long distance systemic signaling from root to shoot and back again, which allows legumes to limit the number of root nodules formed based on available nitrogen and previous rhizobial colonization (PubMed:30351431).
What are the official names of this protein?
Hydroxyproline O-arabinosyltransferase PLENTY.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: FOLD_BACTN
Sequence: MTLIDGKAISEQVKQEIAAEVAEIVARGGKRPHLAAILVGHDGGSETYVAAKVKACEVCGFKSSLIRYESDVTEEELLAKVRELNNDDDVDGFIVQLPLPKHISEQKVIETIDYRKDVDGFHPINVGRMSIGLPCYVSATPNGILELLKRYEIETSGKKCVVLGRSNIVGKPMASLMMQKAYPGDATVTVCHSRSKDLVKECQEADIIIAALGQPNFVKEEMVKEGAVVIDVGTTRVPDASKKSGFKLTGDVKFDEVAPKCSFITPVPGGVGPMTIVSLMKNTLLAGKKAIYK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MUTS_BURO0
Sequence: MTTLSPEAFAGHTPMMQQYLRIKADHPDTLVFYRMGDFYELFFEDAEKAARLLDLTLTQRGASAGTPIKMAGVPHHAVEQYLAKLVKMGESVAICEQIGDPATSKGPVERKVVRVVTPGTLTDAALLSDKNDVYLLAMCTGHNKRGVAVNIGLAWLNLASGALRLAEIEPDQLAAALERIRPAEILTPDGATDAIPAGAGASKRVPAWHFDIASGTQRLCDQLDVASLDGFGAHSLTSACGAAGALLLYAAATQGQQLRHVRSLKVENETEYIGLDPATRRNLELTETLRGTESPTLYSLLDTCCTTMGSRLLRHWLHHPPRASVAAQSRQQAIGALLDAPANASLDALRSALRQIADVERITGRLALLSARPRDLSSLRDTFAALPALRERISAIVANADALARVDAALAPPAECLDLLTSAIAPEPAAMVRDGGVIARGYDAELDELRDISENCGQFLIDLEARERARTGIANLRVEYNKVHGFYIEVTRGQTDKVPDDYRRRQTLKNAERYITPELKTFEDKALSAQERALARERALYDSVLQALLPFIPECQRVASALAELDLLAAFAERARALDWVAPTFTDEIGIEIEQGRHPVVEAQVEQFIANDCRFGTERKLLLITGPNMGGKSTFMRQTALIALMAYVGSYVPAKSACFGPIDRIFTRIGAADDLAGGRSTFMVEMTEAAAILNDATPQSLVLMDEIGRGTSTFDGLALAWAIARHLLAHNACYTLFATHYFELTQLPAEFPQAANVHLSAVEHGHGIVFLHAVNEGPANQSYGLQVAQLAGVPAPVIRAARKHLAYLEQQSASQHTPQLDLFSAPPAAVDDLECADAPALPDTPHPALEKLRDIDPDDLKPREALDLLYELRTLVRSHDADGHA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: LPXD_PROMM
Sequence: MRFSQLIASLQQGSAGLQDHQLAEDPELLSGASLDQAKANQLSFLEQGNALTTQLSHSKVGAVLIPPQDDLRVIAEQRGLAFAVLRDPRLAFAEALEQLHPRSRPKAGVHPTAVIGDQVHLGQGISIGAHVVIGDGSRIGAYSVVHPGVVIYEDVVVGEANELHANAVLQPGSRLGLNCVVHSNAVVGSEGFGFVPTANGWRKMPQTGLVVLEDGVEVGCGSTIDRPSVGETRIGAGTKIDNLVQIGHGVVTGQGCALASQVGIAGGARLGEGVILAGQVGVANRAVIGDRAIASSKSGIHGEVEAGEVVSGYPAIPNRLWLRCSATFSKLPEMAKMLRKLTRDTPQ
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: IHFB_SHEDO
Sequence: MTKSELIEKLATRQSQLSAKEVESAIKEMLEQMATTLEGGDRIEIRGFGSFSLHYRAPRTGRNPKTGTSVELDGKYVPHFKPGKELRERVDAVNV
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: CARA_HAEDU
Sequence: MFNPAILVLADGSTFYGKSIGYQAVSAYSIGEVVFNTAMTGYQEILTDPSYAKQIVTLTYPHIGNTGTNDEDNESNQIYASGLIIRDLPLLHSNFRATSSLSDYLIQHNIIAIADIDTRRLTRILRETGSQAGCIYIPNENESLAQAVEKAQDLAKSFGSMAGKDLAKEVTCQHRYEWQEGIWHLPTNNAGKPFNLQTTPTFHVVAYDFGIKQNILRMLAERGCKITVVPAQTSAEDILALNPDGIFLSNGPGDPEPCTYAIQSIRQLLNTQKPIFGICLGHQLLGLAVGAKTRKMAFGHHGANHPVQDLKTEHVLITSQNHGFEIDEYSLPENVIVTHRSLFDNSVQGIELTNQVAFSFQGHPEANPGPQDVAYLFDKFINAVQATKA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: LOLD_PSET1
Sequence: MNDLVISCENLNKVYQDGSNQVAVLKGVDLALQQGEMLAIVGSSGSGKSTLLHILGTLDTATSGSAKIKNQEVAKLSRTEQAAFRNKNLGFIYQFHHLLMEFSAVENVAMPLLIKGLSAKAAKVAALEMLEKVGLAHRSSHKPSALSGGERQRVAIARALVTKPALVLADEPTGNLDKQNAIKIYDLINELNKSLNTSFVVVTHDLELADKLGKIAYLDDGKLTIKESQHVA
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SUS7_ORYSJ
Sequence: MASKLSFKRMDSIAETMPDALRQSRYQMKRCFQRYVSKGKRLLKNQQLMEELEKSLDDKVENEKLVEGFLGYIICSTQEAVVLPPFVAFAVRMNPGIWEYVKVHSDDLSVEGITPSEYLKFKETLYDEKWAKDDNSLEVDFGALDLSTPHLTLPSSIGNGLQFVSKFMSSKLGGKPESMKPLLDYLLTLNYRGEKLMINDTIDTVSKLQTALLLAEVFVSGLPKYTPYLKFEQRFQEWGLEKGWGDTAERCKETLNCLSEVLQAPDPTNMEKFFSRVPSIFNIVIFSIHGYFGQEKVLGLPDTGGQVVYILDQVRAMEEELLQRIKQQGLHVTPKILVLTRLIPDAKGTKCNVELEPVENTKYSHILRVPFKTEDGKDLRQWVSRFDIYPYLERYAQNSCAKILDILEGKPDLIIGNYTDGNLVASLLSNKLCVTQGTIAHALEKTKYEDSDVKWREMDQKYHFSCQFTADMISMNTSDFIITSTYQEIAGSKEKPGQYEHHYAFTMPGLCRYATGINVFDPKFNIAAPGADQSIYFPFTQKQKRLTDLHPQIDELLYSKDDTDEHIGYLADRNKPIIFSMARLDKVKNITGLVEWYGQNKKLRDLVNLVVVAGLLDASQSKDREEIEEINKMHNLMDRYQLKGQIRWIKAQTDRVRNGELYRCIADTKGAFVQPALYEAFGLTVIEAMNCGLPTFATNQGGPAEIIIDGVSGFHVNPINGREAGIKIADFFQKCKEDPSYWNKVSTAGLQRIYECYTWKIYATRVLNMGSTYSFWKTLNKEERQAKQRYLQIFYNVQYRNLAKAVARAGDQQARQTTTGVAPSEIVVRPKERKPQTRMQRILTRLAGQKPPVSE
What is the function of this protein?
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.
What are the official names of this protein?
Sucrose synthase 7, OsSUS7, Sucrose-UDP glucosyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: AROK_ESCF3
Sequence: MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTGADVGWVFDLEGEDGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQVEAPPREVLEALANERNPLYEEIADVTIRTDDQSAKVVANQIIHMLESN
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 1, SK 1.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_RHIEC
Sequence: MTATDPVANLQTLIRCPSVTPAEGGALTALDAMLTPLGFTVDRVTAREEGTAAIENLYARLGRDGPHLMFAGHTDVVPVGDEAAWTHPPFAAEISNGELFGRGAVDMKGGIACFVAAVARHIEKSGPPAGSISFLVTGDEEGPAINGTIKLLQWAAERGERWDACLVGEPTNPDRLGDMIKIGRRGSLSGKITVHGVQGHAAYPHLADNPVRGLLQLTQALMDPPFDGGTDDFQPSNLEVTTVDVGNPATNVIPAKASASFNIRFNDSWTVETLRAEILRRLEAAAGNGQLRPGRPPAKYDIVWADRPSHVFLTRNNALIASLSSAIESVAGRSPALSTTGGTSDARFIKDYCPVVEFGLVGQTMHMVDERVAVADLETLTAIYQTFIDRWFAHAGS
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: EMTA_SHIFL
Sequence: MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: TRUA_NANEQ
Sequence: MYYYKFWYFRPNKAIAQLIKGKWISRTDKYVSARENYFYGNIPKVLPKNVILLGEEPINKVLSKEYKYFLPKDKAIEQISYLHKVGNIIVRKTKIKVKGLPNLDLMKEAAKHFIGKKDFTNFTIEREAKNPLCTIIKFDIEERKDYYVFSIVGDRFLYHMVRKIISFIVSVGYKIYPLEYIDLVFKERLNPKPKDADPKFLWLWKINKT
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CYO17_VIOOD
Sequence: GIPCGESCVWIPCISAAIGCSCKNKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cycloviolacin-O17.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: SYH_SYNWW
Sequence: MQVKAPRGTYDILPQDSVKWQYIEKIMRDSAESFGFRAIRTPLFEHTELFQRGVGQGTDIVSKEMYSFNDRSQRSLTLRPEGTAPCARALIEHGIYSGVMPVKWYYLGPMFRYDRPQTGRYRQFHQFGVEAFGSNSPYLDAEIIILLVEILRRLGLDDYELHLNSLGCSVCRDDYRQKLLQHISPFKEQLCQDCQQRYMQNPLRVLDCKMETCHQAIRGYPIFYDHLCPYCQEHYSRVQAALQANGISYIHDNNLVRGLDYYSNTAFEIHLPGIGAQSAVGGGGRYDGLVKELGGPDIPGIGFALGMERLLLALDMLGKSKFSNPSLDVFVVVMNDAYEMQGLQLVNELRRRGIRADKDYGGRSGKAQMKYAGKTAARFVVMVGEEEVEKHFWTLRDMQSKEQWQLGQEELISSIRSVIETK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIW_ACET2
Sequence: MLLKTKHFGEINIDESKIIEFKDGIPGFENLKRYVVLYDGDKNSPFRWLQNVDDGELAFAVVNPFMVVKDYDFEIPDEAVESLGIESILDVMVLSIVVVPEDISKMTMNLKAPVIINTKNNKGMQVVLDTDRYSVRHYIIEELRRQEVNVGAGSDEKEK
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OADC_RHOPT
Sequence: MAWRDRRGALRAILTGSACVRPASVYDAISIRIADDLGFPFGMFGGSVASLAILGDPDIALITLTELAEQVRRMSRAAALPVVVDADHGYGNALNVRRTVEELEAAGAAGLTIEDTLLPQAYGEAKPQLVSREEGLGKITAALDARRDPNLVIIGRTGACSITSLDDAIERALAYQAAGVDALFFTGVKTRAQLEAISAATTLPIALGSPPAELGDFDHLAERRVRIAVQGHAPIAAATEAVFKTLSAIKDGAAPKALTGLASAELMDKVTRADVVAERGEHFLGVKR
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate into pyruvate.  Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
What are the official names of this protein?
Oxaloacetate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
Protein: SYV_BORBR
Sequence: MTDAAPNQPVNESQELSKSFEPAEIETRWYDEWAKRGYFDAGRHVETGTDPQPYVIQFPPPNVTGTLHMGHAFNQTIMDGLVRYHRMLGDDTVFVPGTDHAGIATQIVVERQLDAQKVSRHDLGREKFVEKVWEWKEQSGSTITGQVRRLGASADWPREYFTMDARMSRGVAETFVRLYQQGLIYRGKRLVNWDPKLLTAVSDLEVQSEEVDGHMWHILYPFVDGPQTIIDAEGNTVTLRGMTIATTRPETMLADGALCVHPDDPRYKHLLGKLVELPLCDRNIPIIADDFVDPDFGTGCVKITGAHDFNDYACALRHDIPLIVIFTLDAHINENGPKQFQGLERYEARQAVVAELQAQQYLVKVEPHKMMQPKGDRTGVVLEPMLTDQWFVAMSKPAPAGTLNPGKSITEVALEAVADGRIAFYPENWTTIYNQWLNNIQDWCISRQLWWGHQIPAWYSEDGQVFVARSEQEAQEQARAAGVAGPLTRDPDVLDTWFSSALVPFTTFGWPEDTPDLRRYLPSSVLVTGFDIIFFWVARMVMLTMHMTGSVPFKHVYVHGLIRDADGQKMSKSKGNTLDPVDLIDGIDLEGLVRKRTFGLMNPKQAGAIEKATRRQYPDGIPAFGTDALRFTMAAYATLGRNINFDLKRCEGYRNFCNKLWNATRFVLMNTEGHALDGDGGELSFADRWIVSQLQALEAEVERGFADYRFDNVANALYRYVWDEYCDWYLELAKVQIQQGTPAQQLGTRRTLIRVLEAVLRLAHPVIPFITEELWQKVALVAGKRTAGAVASVSVQPYPRANPQAVDAEAEAAVAELKSQVEAVRALRGEMNLSPAQRVPLVAEGPTDVLSRNAPYLAALAKLSEVEVVAALPDAGAPVQVVGDARLMLHVEIDVAAECARLDKEIARLEGEIAKANGKLGNASFVERAPAAVVEQEKARLAQFSETLEKVRGQRVKLGA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHE2_STAAW
Sequence: MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
What are the official names of this protein?
NAD-specific glutamate dehydrogenase, NAD-GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: SV2B_MOUSE
Sequence: MDDYRYRDNYEGYAPSDGYYRSNEQNQEEDAQSDVTEGHDEEDEIYEGEYQGIPHPDDVKSKQTKMAPSRADGLGGQADLMAERMEDEEELAHQYETIIDECGHGRFQWTLFFVLGLALMADGVEIFVVSFALPSAEKDMCLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSHIKTPKQMDEFIEIQSSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRMNTLILAVVWFTMALSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKLVNDKFIKMYFKHVLFEDTFFDKCYFEDVTSTDTYFKNCTIESTTFYNTDLYKHKFINCRFINSTFLEQKEGCHMDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLVGGGLIALRLPETREQVLM
What is the function of this protein?
(Microbial infection) Receptor for C. botulinum neurotoxin type E (BoNT/E); the toxin probably binds via extracellular loop 4 (PubMed:18815274).  It probably requires glycosylation of Asn-516 (PubMed:18815274).
What are the official names of this protein?
Synaptic vesicle glycoprotein 2B, Synaptic vesicle protein 2B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Associated with synaptic-like microvesicles but not with insulin-containing vesicles in insulin- secreting cells of the pancreas (By similarity). Localizes to microvesicles in the pinealocytes. Localizes to the acrosome in spermatids (By similarity).
Protein: RS7_SULNB
Sequence: MRRRKAPVRPVLPDPVYGSKVLTKFINAVMLDGKKSTAQKVMYSALERIESKTGEKGIEVFNKAMDNIKPVMEVKSRRVGGATYQVPIEVRPARQQSLGIRWIVEAARKRNERTMMERLSNELMDAATEKGSAFKKKEDTYKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL16_BACCZ
Sequence: MLMPKRVKYRREHRGKMRGRAKGGTEIAFGEFGLQAQAASWITNRQIEAARRAMTRYMKRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKIMFEIAGVSEEVAREALRLAAHKLPVKCKFVKREENGGESNEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.