PharMolix/UniProtQA huggingface dataset:
Protein: CRG11_LITCT
Sequence: MGKIIFYEDRNFQGRSYECSNDNPDLQPNFNACNSVRVENGCWMIYERPNYMGHPYFLKRGEYPDYQQCQGLNDSIRSSRLLSQNLGIGTNKLRVYERGDSKGEMMEFLEDCPNVYDRFCSHEIHSCNVLDGYWIFYELPNYKGKQYLLRPGEYKRFTDWGSQTAKVGSFRRVIDIC
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin M1-1, Gamma M1-1.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: SRR55_DROME
Sequence: MVGSRVYVGGLPYGVRERDLERFFKGYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKELLGERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLSSRVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVEDRRGGRSGGGGGSGRGRSRSSSSRSRSRSRRRSRSRRSSHSRSKSRSRSKSRGGRSKSKSPVKSRSRSRSRSNKSRDVSKSKSKSHSRTRSRSPKRERDSRSRSRSVSKRESRSRSRSKSIHRDSRSRPPTVSFKSSFYKFTTMPFFCSDRSASAENKSRSRSRSRSASPKNGNASPDRNNESMDD
What is the function of this protein?
Essential for development.  May have a critical role in splicing or in controlling alternative splice site use of at least some pre-mRNA in vivo.  Not required for all splicing.  May play a general role in the condensation or decondensation of chromatin.
What are the official names of this protein?
Serine-arginine protein 55, SRP55, 52 kDa bracketing protein, B52 protein, Protein enhancer of deformed.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus. Note=Associated with boundaries of transcriptionally active chromatin.
Protein: METXS_BURCM
Sequence: MESIGIVAPQTMHFAEPLRLQSGSVIGNYQLVVETYGELNAARSNAVLVCHALNASHHVAGVYADDPRSTGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSIDPSSGKPYGARFPVVTVEDWVHAQARVADAFGIERFAAVMGGSLGGMQALAWSLMYPERVAHCIDIASTPKLSAQNIAFNEVARSAILSDPDFHGGDYYAHGVKPKRGLRVARMIGHITYLSDDDMAEKFGRALRRADGALDAYNFSFDVEFEVESYLRYQGDKFADYFDANTYLLITRALDYFDPAKAFDGNLTAALAHTQAKYLIASFSTDWRFAPARSREIVKALLDNKRTVSYAEIDAPHGHDAFLLDDARYHNLLRAYYERIANEVGA
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_RHOCB
Sequence: MQVTQTLNEGLKRGYTITLTGAELDAKVTEKLIEVQPEVEIKGFRKGKVPMAMLRKNFGDRVLGDVLNESVDGAIKDLLDQSGDRPALQPKVEMENGKDWKPGTDAIFTVSYEALPPIPAFDRATVTLERLVVKADEASVTEALENLAKSAQAFEDRKKGTKAKDGDQVVIDFEGFLGDEPFEGGKGEEYPLVLGSNSFIPGFEDQLVGAKAGEDVEVKVTFPAEYGAAHLAGKEATFKCHVHAVKAPKPAEIDDELAKKFGAADLEALKGQVASRLEAEYKGASRAILKRALLDILDAQVKFDLPPSLVEAEAGQIAHQLWHEENPDHHGHDHGAVEPTEEHKTLAERRVRLGLLLAELGRNEKIEVTDAEMTQAVLAAARQYPGHEREFFEFVKGNAQMQQQIRAPLYEEKVIDFIVAGAAVTEKEVSKEELQKAIEALDEL
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: Y400_DEHMC
Sequence: MSGHSKWATIKHAKGAADAKRGQLFTKLSREIIFAAKQGGPSPEGNARLRLAIQKAKDSRMPSDNIERAIKKGSGELEGTTVIEMILEGYGPGGVAVLVNGMSDNRNRTVSDVRHMFSKGGGSLAESGAVSWIFEAKGVIGVETAGLDTDELSLKAIDMGAEDVNTDEGYMEIYTAMPDMEKIRQQLETQGVTIDSAEINMVPKNTVKLDEETAMQVLKLLDKLEELDDVQTVSSNADFDPEVVEKYHSQA
What are the official names of this protein?
Probable transcriptional regulatory protein cbdbA400.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSP1_CANGA
Sequence: MSAEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLAFHTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCGIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMQQYQQEMEQATALPLPDEDDADL
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein GSP1/Ran.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_CUCSA
Sequence: MAFAKAQKTKAYFKRYQVKFKRRREGKTDYRARIRLINQDKNKYNTPKYRFVVRTSNKDITAQIISASIAGDLVLASAYSHELPQYGLEVGLTNYAAAYCTGLLLARRVLKMLEMDAEYEGNVEATGEDYSVEPADTRRPFRALLDVGLIRTTTGNRVFGALKGALDGGLDIPHSDKRFAGYAKNGQQLDVEVHRKYIFGGHVAAYMRTLMEDEPEKYQSHFSEYIKKGIEADELEGLYKKVHAAIRANPIAKKSDKPQPKAHKRYNLKKLTYDERKARLVERLNALNSAADGDDDDDEDDE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ISPE_DEIGD
Sequence: MPPECGGPPMPLDPLTLRPLAPSETATYLAPAKVNLGLSVRGLRTDGYHELHSVMVPLVVGDELEIAAADTLTLRVEGAALPTDERNLVYRAARAYLDAAGVSGGATITLRKRLPLASGLGGGSSDAATTLMALARLFPAPVNLPALALTLGADVPFFLLGQAALAQGIGDVLTPLPVPQVPLVLVNPGVEVSARDAYAWLDEEEAFTPPLDVEGLLAALTAQHELPTFNALQGPVAARHAPIQAALAALSSAGLRSPLMSGSGATCFALAASDAQAHAAAQALQAQHPAWWVVATRTL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: TXG1A_SCODE
Sequence: MTTSATVIIMVLCVGSLVIFSEGSIGFELVTPLPGKPDECPVEDGRTLAIGQTEQVPGQCEERTCIKMDDQLYFELAGCGISEAGPGCEMFESKAETYPECCTPEIKCN
What are the official names of this protein?
U-scoloptoxin(16)-Ssd1a, U-SLPTX(16)-Ssd1a, Toxin SSD377.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YB69_YEAST
Sequence: MTLLNTLSNFGGTWPRLIIMSMINYFTVYQCTIPGTNKVYVTHGGSMQACTELLNGTVTILRDGYYITNLICIVVGLFLYFGYLKRKILHLQSLPISSWRFFHFFFTILAVTSRAIYYKSQNWRREC
What are the official names of this protein?
Uncharacterized protein YBR219C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SPZ2B_ORYSJ
Sequence: MEDDAGNCGGLTAFALRLAKRLADDGDNSNRNVVFSPVSLYAALALVASGARGTTLDELVALLGAASLDDLEESVRRAVEVGLADESESGGPRVSYACGVWHDERLALKPAYRAADFQRQPKSSRKKINKWVSKATNKLIREILPDGSVHGGTALVLVNAIYFKGKWSNPFPRERTTTGKFHRLDGSSVDAPFMSSREDQYIGFYDGFKVLKLPYHRTMKNHGDGGDITPAILKHYGENVGLSMYIFLPDARDGLPALVDKMAVASSGTASSSFLRDHRPGRRRIKVGDLRVPRFKVSFYSEMNEVLKGMGIGAAFDVGKVDLSGMIDGELVVVEKVMHRAVVEVNEEGTEAAAATACTMKFLCLTLTSPVDFVADHPFAFFVVEEKSDAVLFAGHVLDPTSLE
What is the function of this protein?
Probable serine protease inhibitor.
What are the official names of this protein?
Serpin-Z2B, OrysaZ2b.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: RS15_METEP
Sequence: MSITAERKTALIKDYAKGNKDTGSPEVQIAILTERITNLTAHFKTHGKDNHSRRGLLKLVSQRRSLLDYLKRKEEARYRTLIERLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HFLD_SHEPC
Sequence: MNEQLINRTMAFAGILQAIAQVQHLARHGELDNAELAASLNTILVTNPDNTADVYPDKIVLQKGYKLILNQLGDSSQKDVEITRYLVGVLALERKLVRSNSGLGMLAERINQVNRQLHHFAITDEQVVANLASIYSDIISNLGPKIQISGNPVCLQRPIVQHKIRALLLAAIRSAVLWRQLGGKRRHLVFARKAIVDTAKKSLTL
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FRDB_PROVU
Sequence: MADDMKHVKMEVMRYNPETDDAPHFVTYDVPYDEQTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNRVPKLACKTFMRDYPNGVRIEALGNFPVERDLVVDMTHFIESLEAIKPYILGNDRKPSEGPNKQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAQRYNTDSRDHGAKERMPQLNGENGVWSCTFVGYCSEVCPKHVDPAAAIQQGKAASAQDFVIAMLKPR
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
What are the official names of this protein?
Fumarate reductase iron-sulfur subunit, Quinol-fumarate reductase iron-sulfur subunit, QFR iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PAL1_FRIUN
Sequence: MAHIGNGNGNGNGFANGNGNGNGAAGLCLHPDPLNWRAAADALTGSHLDEVRRMAAEFRKPVVRLEGASLSISQVAAVAAGREVKVELSEEARGRVKASSDWVMDSMGKGTDSYGVTTGFGATSHRRTKEGGALQKELIRFLNAGIFGAGPEDGQTLPPTTTRAAMLVRVNTLLQGYSGIRFEILEAISSLLNHNVTPILPLRGTISSSGDLVPLSYIAGVLIGRPNSKSIGPDGTYVDATEAFRLAGISGGFFELQPKEGLAMVNGTAVGSGLASMVLFEANIIAVLAEVISAIFCEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILAGSSYMKMAAKIHEQDPLQKPKQDRYALRTSPQWLGPLIEVIRTSTKSIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLVLAAIGKLMFAQISELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISARKTAEAVEILKLMSSTFLVALCQAVDLRHLEENLKAAVKNTVSQVAKRVLTMGVNGELHPSRFCEKDLIKVIDREYVFAYADDPCSATYPLMQKLRGVLVEHALVNGDKEKEMGTSIFQKITAFEEELKATLPKEVEGVRVAFDNGTNVIPNRISECRSYPLYKFVREELGAGYLTGEKVVSPGEEFNKVFVAMNQWKLIDPLLECLSDWNGAPLPIC
What is the function of this protein?
Key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton (By similarity).  Can use L-phenylalanine (L-Phe) as substrate more efficiently than L-tyrosine (L-Tyr) (PubMed:35643154).  Promotes drought tolerance by inducing the biosynthesis and accumulation of salicylic acid (SA) and lignin (PubMed:35643154).
What are the official names of this protein?
Phenylalanine/tyrosine ammonia-lyase 1, FuPAL1.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
Protein: GMFG_MOUSE
Sequence: MSDSLVVCEVDPELKETLRKFRFRKETNNAAIIMKVDKDRQMVVLEDELQNISPEELKLELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRTTDDLTETWLKEKLAFFR
What are the official names of this protein?
Glia maturation factor gamma, GMF-gamma.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. GMF subfamily.
Protein: LBD19_ARATH
Sequence: MMTGNLNGGGRGGEGPCGACKFLRRKCVKGCVFAPYFDAEQGTARFAAVHKVFGASNASKMLLRLPLHKRLDAVVTLCYEAMARIRDPVYGSVGHLFSLQHQVMNLQAELAHVQARLSTIQRFPLQSPQQMQPPSFDPAHNNEYAMEPSNLDSVWGEEHLLQDGTGDGDFQELASQFVSRYLPAVKLPACT
What are the official names of this protein?
LOB domain-containing protein 19, ASYMMETRIC LEAVES 2-like protein 23, AS2-like protein 23.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
Protein: TCPZ_CAEEL
Sequence: MSSIQCLNPKAELARHAAALELNISGARGLQDVMRSNLGPKGTLKMLVSGAGDIKLTKDGNVLLHEMAIQHPTASMIAKASTAQDDVTGDGTTSTVLLIGELLKQAESLVLEGLHPRIVTEGFEWANTKTLELLEKFKKEAPVERDLLVEVCRTALRTKLHQKLADHITECVVDAVLAIRRDGEEPDLHMVEKMEMHHDSDMDTTLVRGLVLDHGARHPDMPRHVKDAYILTCNVSLEYEKTEVNSGLFYKTAKEREALLAAEREFITRRVHKIIELKKKVIDNSPDGKNKGFVVINQKGIDPPSLDLLASEGILALRRAKRRNMERLQLAVGGEAVNSVDDLTPEDLGWAGLVYEHSLGEEKYTFIEECRAPKSVTLLIKGPNKHTITQIKDAIHDGLRAVFNTIVDKAVLPGAAAFEIAAYVMLKKDVENLKGRAKLGAEAFAQALLVIPKTLAVNGGYDAQETLVKLIEEKTAAGPDIAVGLDLETGGAVEPQGIWDNVTVKKNSISSATVLACNLLLVDEVMRAGMTNLKQPQPE
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
What are the official names of this protein?
T-complex protein 1 subunit zeta, TCP-1-zeta, CCT-zeta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1987_MYCTO
Sequence: MAGLNIYVRRWRTALHATVSALIVAILGLAITPVASAATARATLSVTSTWQTGFIARFTITNSSTAPLTDWKLEFDLPAGESVLHTWNSTVARSGTHYVLSPANWNRIIAPGGSATGGLRGGLTGSYSPPSSCLLNGQYPCT
What are the official names of this protein?
Uncharacterized protein MT2041.
Protein: RGT1_YEAST
Sequence: MNELNTVSTNSSDSTKNGGTSNSPDDMDSAAAASHAIKKRTKASRACDQCRKKKIKCDYKDEKGVCSNCQRNGDRCSFDRVPLKRGPSKGYTRSTSHPRTNEIQDHNNSRSYNTFDNSNNTLNNNTGNSGDNGINSNTVPSTPSRSNSVLLPPLTQYIPQAGGIPPSFQNPAIQSTMPAGNIGQQQFWKVPYHEFQHQRKGSIDSLQSDISVRTLNPNEQLSYNTVQQSPITNKHTNDSGNANGSVTGSGSASGSGGYWSFIRTSGLLAPTDDHNGEQTRRSSSIPSLLRNTSNSLLLGGQPQLPPPQQQSQPQAHQQKLQQGQNLYSYSQFSQQQPYNPSISSFGQFAANGFHSRQGSVASEAMSPSAPAMFTSTSTNPVNVAQQTQRPQGQQVPQFSSELDGNKRRQSAPVSVTLSTDRLNGNENNNGEINNNNGSNNSGSSKDTSQHSQESVTTPAALEASSPGSTPQRSTKKRRKSYVSKKTKPKRDSSISITSKDSAHPMTTSSTIAYGQISDVDLIDTYYEFIHVGFPIIPLNKTTLTSDLLLVNTQPISNIHEVNSYVILWFRNSLELLVRVALKQKPGGKFFDNIVGVALSPSNDNNKAGFTTATARDDAEKTRRDSHNEVQDTLEVQSVFIAALNECFQKIVDIHPKFRENNDQISPKIKVIYLSTFILLNYILAFVGYDNSFVLGMSVTIFNEFKLYKLLLFPEPDINDVKPPVDEEVSTGNGNTKTSEFEIGSESAGHMNPSNSPNSMDENISHYSVLFKRLYVLLSVFDSLQSCAFGGPKLLNISIQGSTERFFSNDLGSKWCLEQSQLRLKSVLQSLKLGELMSELTRNRISMNGNRKPGFDITNSSSLLSEYVETQPLSVAQLFCKLLIGKHNFINCLLSLYDSEAGVYSDLTLDLSSKIADSLCSLISIILQVLTLILRLNPTNSIDFNYRPPNPPANNPTVQEGPSAMGSSPVAGNLSAAPPSEGNPDFYKKLLGLKQDTGTILSDLCRGIISPFAIAILHEVYNITELVKQMPTSLISIMMTATTTQNTQDTKKSQDLVMKLSNSMNEVVQITSVLTMIKPFKIFEHELNKPIMSLTGGLSSTTRNDVMWPKSGQGLRESSVMKTLLDERRTSGTQPTTAPVAAEEPRLENVALENFVSIGWKLLDDSELGWY
What is the function of this protein?
Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose.  In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator.  In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription.  Binds the consensus binding site sequence 5'-CGGANNA-3', of which multiple copies are present in all HXT promoters regulated by RGT1.
What are the official names of this protein?
Glucose transport transcription regulator RGT1, Restores glucose transport protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDS1/RGT1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LNT_RHOPA
Sequence: MTRRGVLSRIASGIILAWGWKRAVIALLAGALSSLAMEPFNAWPVLFITFPIAVWLIDGSAAGKRRGVPAAAMAGWWFGFGYFVPGLYWIGYAFLVDADTFAWLLPAAICGLPAYLALFTALGFALARLLWRPDSLRILSLAVSLTISEWLRGHLLTGFPWNAFGYALTEPLVLAQSISVIGIWGLTLLTVAIFASPAVLIDGGTNTRRRWAVPAMALGVLAAMTVFGGIRLKLSPTQLVDNVRLRIMQPNLPQDARFNYSAKADVMQKYLSLSDRSTGPKSTGVRDVSLLIWPESAFPFFLSREADAMAQIAELLPKGTVLLTGAVRPPELPPGRRITRAYNSIYAIDHDGSILSVYDKLHLVPFGEFLPYQNLMEKIGFVQLTKVQGGFLSGVARHNLELPNAPPLLPLICYEAIFPDEIAIGNNRPGWMLNLTNDGWFGISSGPYQHLQQARMRAIEQGLPLVRAANTGVSAVIDPVGRIVAELGLGVEGVLDSGLPAPVAPTIYARVGELPAAVLVALVMMLVLLRKRPPGS
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECO_RHILW
Sequence: MQWQDHAIILGVKRHGETSVIAEVMTRDRGRHLGLVRSGRSRAMQPVLQAGNAVEVIWRARLDEHLGEFRVEPVTLRAARLMETATAVYGVQAMGALLRLLPERDPHPHLFDALEVILDHLHNPADAGELFVRFELAVLNDLGFGLDLAECAATGARSDLAYVSPKSGRAVSRSAGAPWADKMLLLPPFLGIEGNHAADFDSLSAAFRLTGFFLHRHVYEPRGIEAAAARDGFVQAALKALNPALRTLSGPNDISA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: CH10_HELP2
Sequence: MKFQPLGERVLVERLEEENKTSSGIIIPDNAKEKPLMGVVKAVSHKISEGCKCVKEGDVIAFGKYKGTEIVLDGTEYMVLELEDILGIVGSGSCCHTGNHDHKHAKEHEACCHDHKKH
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_BLOPB
Sequence: MELEVRDFTTEINILDSEKFSVSDEIFKCPFNQALIHQVISTYLTNSRQGTRSQKSRSEVSGSNKKPWRQKGTGRARSGSVKSPIWRSGGVTFAAKPKLYAQKINKKMYRGAIRSILSKLVCDNRLFLVRNLFIKEPKTKLLLEKLRTITSKKSILIFTDFLDKNLLLASRNVHKIEVRTATHIDPVSLINFNVTLIADNVIKKIEKQLV
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: XYLJ_PSEPU
Sequence: MDKTLINELGDELYQAMVQRETVTPLTSRGFDISVEDAYHISLRMLERRLAAGERVIGKKIGVTSKAVQNMLGVHQPDFGYLTDAMVYNSGEAMPISEKLIQPRAEGEIAFILKKDLMGPGVTNADVLAATECVIPCFEVVDSRIQDWKIKIQDTVADNASCGLFVLGDQAVSPRQVDLVTCGMLVEKNGQLLSTGAGAAALGSPVNCVAWLANTLGHFGIA
What is the function of this protein?
Conversion of 2-hydroxypent-2,4-dienoate into 4-hydroxy-2-oxopentanoate.
What are the official names of this protein?
2-hydroxypent-2,4-dienoate hydratase, HPH, 2-oxopent-4-enoate hydratase.
What is the protein family that this protein belongs to?
Belongs to the hydratase/decarboxylase family.
Protein: FXR1_BOVIN
Sequence: MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDYKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRESRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDEISKLQRTPGEEKINTLKEENTQDAAVLNGVS
What is the function of this protein?
mRNA-binding protein that acts as a regulator of mRNAs translation and/or stability, and which is required for various processes, such as neurogenesis, muscle development and spermatogenesis.  Specifically binds to AU-rich elements (AREs) in the 3'-UTR of target mRNAs.  Promotes formation of some phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to AREs-containing mRNAs, leading to assemble mRNAs into cytoplasmic ribonucleoprotein granules that concentrate mRNAs with associated regulatory factors.  Required to activate translation of stored mRNAs during late spermatogenesis: acts by undergoing liquid-liquid phase separation to assemble target mRNAs into cytoplasmic ribonucleoprotein granules that recruit translation initiation factor EIF4G3 to activate translation of stored mRNAs in late spermatids (By similarity).  Promotes translation of MYC transcripts by recruiting the eIF4F complex to the translation start site.  Acts as a negative regulator of inflammation in response to IL19 by promoting destabilization of pro-inflammatory transcripts (By similarity).  Also acts as an inhibitor of inflammation by binding to TNF mRNA, decreasing TNF protein production.  Acts as a negative regulator of AMPA receptor GRIA2/GluA2 synthesis during long-lasting synaptic potentiation of hippocampal neurons by binding to GRIA2/GluA2 mRNA, thereby inhibiting its translation.  Regulates proliferation of adult neural stem cells by binding to CDKN1A mRNA and promoting its expression.  Acts as a regulator of sleep and synaptic homeostasis by regulating translation of transcripts in neurons.  Required for embryonic and postnatal development of muscle tissue by undergoing liquid-liquid phase separation to assemble target mRNAs into cytoplasmic ribonucleoprotein granules (By similarity).  Involved in the nuclear pore complex localization to the nuclear envelope by preventing cytoplasmic aggregation of nucleoporins: acts by preventing ectopic phase separation of nucleoporins in the cytoplasm via a microtubule-dependent mechanism (By similarity).
What are the official names of this protein?
RNA-binding protein FXR1.
What is the protein family that this protein belongs to?
Belongs to the FMR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD1_ROSCS
Sequence: MKDLFRRAPKRFTAARIENQAIPDNMWVKCPSCGDLIYTRQFSDNLKVCKCGYHMRLAAREWLGLLDDGSFVEFDAALAPVDALEFISPRHVYAHKLSESQEQTGLNDALITGSGAIEGMPLCVAVTEFEFIGGSMGGAFGERLARIIEQAADARVPLLTINASGGARQEEGTLALLQMAKVNMALTRLAAVGQPHIAVLVDPCYGGVLASYTSVADIIIAEPGARIGFAGRRVIEQTIRQKLPAHFQTAEFLLSHGMIDMVTPRGELRSVLATLLRLFHNAPERAADVQNAPALARA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 1, ACCase subunit beta 1, Acetyl-CoA carboxylase carboxyltransferase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.