PharMolix/UniProtQA huggingface dataset:
Protein: MED7_EMENI
Sequence: MAEPGRTFNTAFAPPPPLWKHFTPENLQRLENIKKEASKGEDGRRRKKEWSPAELRSLKIPPELRFLVPPEIPSEQYSIFGEVQNLSTALPSLEEQGITQLYPSSPKPDTKSGDSSQPAQPLNHAYYLLKISKSLLLNFLEFVGILSVAPEQFEPKVEDIRNLFINAHHLLNLYRPHQARESLIMMMEAQLARTKDEIQQMDKLKEEVNAVLDQLAAEGADVGSTIQSTTKDKKGVKPEDQIPEDSKLLWDILDGKLDD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, Mediator complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VSP6_BORHE
Sequence: MRKRISAIIMTLFMVFMSCNNGGPELKSDEVAKSDGTVLDLAKVSKKIKEASAFAASVKEVETLVKSVDELAKAIGKKIKNDDDGFDTEANKNGSLLAGTLQLMFAVGTKLESLEKIAGISDEVRGKVIVVKTENTALITKLKGGDASLGKNDASDSDAKNAIDKSDVTGGKVRKSLFKLNTAVDALLKAAEGEVEAAIKELTAPVKVEKPSQNN
What is the function of this protein?
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time.  Switching between these genes is a mechanism of host immune response evasion.
What are the official names of this protein?
Variable small protein 6.
What is the protein family that this protein belongs to?
Belongs to the variable small protein (Vsp) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SET5_USTMA
Sequence: MVAPSETQIVQAVKAKLESGLTSTSDVVREDEVRRLLATLELEHDWQDIAVKKFISILCKHSLMPVSKPNDGCTSRSTSCPGGKKKKKSKTDTSIPKSFIDPTISFPAGIRGVYFDPVKGKGLVATRSFSKGDLLFTEDAYIPTPPPEAFDQMASGQLCAQCFLPISSAPVALAIKNCSKCKHRFCTTACYKTAMATHHTLLCTGINASAKPLIELIERQKWQSLHCVARSLARLLMTLTRQYHGQANKKADTQDSVATYGDFETVYARLSSFATVSELERRSRNPGWTTEKASFESILVEAHTALCNALDPYSSTRNANLEPFHVSADYLDSTRKPLIKDLFCLATFMKLVGRANINMEKFGGLYSLHSFLNHSCSPNLEIRHVPERAILSSMKVAAIALCDIHPDDELVISYIDPNTSLARRQLLLYRDYCFGPCTCDKCTTQLGALGLVYDPAKHAVKAFLDSVAHKTRPDPDHTLPPTSQDSTLEDQLRASLGF
What is the function of this protein?
Putative protein lysine methyltransferase.
What are the official names of this protein?
Potential protein lysine methyltransferase SET5, SET domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: U51A_SCYTH
Sequence: MKLFVCFLLLAVVVVSAVNASEEMRLKNLLKAVERDETPDECVTRGNFCATPEVHGDWCCGSLKCVSNSCR
What is the function of this protein?
Probable insect neurotoxin with ion channel impairing activity (Probable).  Does not show activity on 45 human receptors from 9 families (5-hydroxytryptamine, adrenergic, dopamine, muscarinic, histamine, neurotransmitter, opioid, sigma, and gaba(A) receptors) (PubMed:27227898).  In vivo, does not cause paralytic or lethal activity when injected into sheep blowflies or crickets (PubMed:27227898).  It is noteworthy that both sheep blowflies and crickets are evolutionarily distant from prey species (PubMed:27227898).
What are the official names of this protein?
U5-scytotoxin-Sth1a, U5-SYTX-Sth1a, U5-Sth1a.
What are the subcellular locations of this protein?
Secreted.
Protein: INHBA_BOVIN
Sequence: MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALATLPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEIWLFLKVPKANRTRSKVTIRLFQQQKHLQGSLDAGEEAEEVGLKGEKSEMLISEKVVDARKSTWHIFPVSSCIQRLLDQGKSSLDIRIACEQCQETGASLVLLGKKKKKEEEGEGKKRDGEGGAGGDEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
What is the function of this protein?
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.  Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.  Inhibins appear to oppose the functions of activins.
What are the official names of this protein?
Inhibin beta A chain, Activin beta-A chain.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF_STRAW
Sequence: MILVQLAAEEAQNPLIPEVPELVIGLLAFAIVFFVLGKKLLPNINKVLEERRAAIEGGIEEAEAMKVEAQSVLEQYKAQLAEARHEAARLRQEAQEQGATLITEMRAEGQRQREEIIAAGHAQLEADRKAAAQALRQDVGTLATDLAGKLVGESLEDHARQSRVIDRFLDGLEEKAEATR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MSHA_RHOOB
Sequence: MVTPLHNSRPRRVAVLSVHTSPLAQPGTGDAGGMNVYVLQSAIQMARRGVEVEIFTRATSSADAPVQEAAPGVLVRNVVAGPFEGLDKQDLPTQLCAFVAGVLREEARHEPGYYNLVHSHYWLSGQVGWLARDRWGVPLVHTAHTLAAVKNLSLAEGDTPEPAARQIGEQQVVAESDRLVANTTEESDQLVRHYGADPNRIDVVAPGADLTRYRPGDRDAARATLGLDPRETVVTFVGRIQPLKAPDVLLRAAAELIARDPASSLRVLVVGGPSGSGLARPDALIELASSLGIAARVTFLPPQAPDRLADVYRASDLVAVPSYSESFGLVAIEAQACGTPVIAANVGGLGVAVRSGETGLLVDGHRTEDWATALQSLVSEPARLAALAAEAPRHAENFSWEHTADGLLESYRMATVNYNYGHGPSEFSPRRGRGLWKLRRAGGVRA
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: LPLT_SALPA
Sequence: MSESVRTNTSIWSKGMLSVIVAQFLSAFGDNALLFATLALLKAQFYPDWSQPVLQMVFVGAYILFAPFVGQIADSFAKGRVMMVANGLKLAGAAGICLGVNPFVGYTLVGIGAAAYSPAKYGILGELTTGDKLVKANGLMEASTIAAILLGSVAGGVLADWHVIAALVACALAYAGAVAANLFIPKLVAARPGQSWRLSAMTRSFFSACVVLWRNGETRFSLVGTGLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAVGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVAIFSLQHALLPAYALLLLIGMLGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGLYSLAVLVGVPAVAIGIGFGVLFALAIAALWIWQRRQASY
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEFA4_ORNAN
Sequence: MKTLCLLFAVLCLVTWTQARGAEVEENLTAQDGEVDIAGDNGDVQLTLNTDDFESFTLKTLTLGHPRVKRHSCVCRRICAARQVRKGRCSRRRRICCLY
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Defensin-A4, DefA4, OaDefA4.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: VG27_EHV2
Sequence: MRNILKVTRFDDGTVQEVVHRDGLRVETYYKSEEGEARANLEQRPPAAADEARTYLSPSSSFSSSSSSSSAVALGARPDLAQGGGRGSERRERGCRWNGCPPLAIVLPVLANLIMCAMLAWYLNPLFSPWVYFNCTNSSLGVGNCSNFFGCSRGNLSVNDSFWPPGSVVFGKDGCAVSASVLGLVGPGVLCNGTGCA
What are the official names of this protein?
Uncharacterized gene 27 protein.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: O268_CONVC
Sequence: MEKLTILLLVAAVLMSTQALMQEQRQKAKINLFSKRRLSAESWWEENGCSLWGPCTVNAECCSGDCDETCIFGS
What is the function of this protein?
Inhibits voltage-gated ion channels.
What are the official names of this protein?
Conotoxin Vc6.8.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSP1_DORMU
Sequence: MARYRHSRSRSRSRYRRRRRRRSRYRSRRRRYRGRRRRRSRRGRRRRGYSRRRYSRRRRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MOC2A_DROAN
Sequence: MSADGPVVNVHVLFFAKSRELAQTPRSKVDVPSQIVASDLLDQLVTRFDLASIKDNLILAHNESYIENLSDKILFREGDELAVIPPLSGG
What is the function of this protein?
Acts as a sulfur carrier required for molybdopterin biosynthesis.  Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group.  In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  After interaction with Mocs2B, the sulfur is then transferred to precursor Z to form molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, Molybdenum cofactor synthesis protein 2 small subunit, Molybdenum cofactor synthesis protein 2A, MOCS2A, Sulfur carrier protein MOCS2A.
What is the protein family that this protein belongs to?
Belongs to the MoaD family. MOCS2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_PECCP
Sequence: MKALHFGAGNIGRGFIGKLLADANVELTFADVNQPLLDALNSRKSYTVRIVGDNTRLDTVSNVSAVHSGSQDAVALIAVADLVTTAVGPQILEKIAGTIAQGLVKRHNDGTTRPLNIIACENMVRGTSQLKQHVLKLLPEGHQEWVVEHVGFVDSAVDRIVPPSEAGSDDVLAVTVETFSEWIVDKTQFCGEPPAIPGMELTDNLMAFVERKLFTLNTGHAITAYLGQQARHQTIRDAILDPKVRAVVKGAMEESGAVLIKRYGFDADKHAAYINKILSRFENPHLHDDVERVGRQPLRKLSAGDRLIKPLLGTLEYHLPHDNLITGIAAAMHYRSEQDPQALELAELLRAQGPQAALAQISGLDADSEVVAQAVNVYNAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: APM1D_ORYSJ
Sequence: MAAAAAEFRGQARLPRFAAPRRYELRLRPDLAACVFSGEASVAVDVSAPTRFLVLNAADLAVDRASIRFQGLAPAEVSVFEEDEILVLEFAGELPLGEGVLAMRFNGTLNDQMRGFYRSKYEYKGETKNMAVTQFESVDARRCFPCWDEPSFKAKFKLTLEVPSELVALSNMPIVNEKIAGPIKTVEYEESPVMSTYLVAIVVGLFDYIEGVTSEGNKVRVYTQVGKSNQGKFALDVGVKSLNLYKEFFDTPYPLPKLDMVAIPDFTNGAMENYGLVTYREIYLLFDEQSSSASTKQNVAITVAHELAHQWFGNLVTMEWWTHLWLNEGFATWMSYLAVDSFFPEWNIWTQFLDSTTSALKLDSLAESHPIEVEIHHASEIDSIFDSISYDKGASVIRMLQSYLGAERFQKALASYIKKYAYSNAKTEDLWAVLEEVSGEPVKNLMTTWTKKQGYPVIGVKLKGHDVELEQDQFLLDGSSDSGMWIVPITLGCNSHDMQKRFLLKHKFSDIKGINSQYDDQDRQNSGNFWIKLNIDETGFYRVKYDDELTTALRNALQMKKLSLMDKIGIVEDAHALSIAGKQTLSSLLHLLYACRDEDDFSVLSHINSVTSSVAKISIDATPELAGEIKQLFIKLLLPTAEKLGWDPKNSESHLDAMLRPVLLVGLVQLGHDKTISEGVRRFQIFFDDRNTSLPPDTRKAAYLSVMHNVSSTNRSGYDALLKIYRESTEVEERLNVLGILSSCQDKDIVLESLNFIFTDEVRNQDAYLVLRSVIIDARETAWSWLKENWDRITKTFAASAILSDYVKSIVTLFTSKEKEAEISQFFATRTKPGFKRALKQSLENVRISARWVDGIRGEAELAQTVHDLLIKL
What are the official names of this protein?
Aminopeptidase M1-D, Alpha-aminoacylpeptide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm. Note=The dileucine internalization motif may be involved in intracellular sequestration.
Protein: MANBL_MOUSE
Sequence: MASDLGFSPPEVPEPTFLENLLRYGLFLGAIFQLICVLAIIVPIPKSHEAEAEQAEPRSAEGPKKPKAAIASTNKRPKKETKKKR
What are the official names of this protein?
Protein MANBAL.
What is the protein family that this protein belongs to?
Belongs to the UPF0239 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ULAR_SHIB3
Sequence: MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNANPEILQQLEAQGVSILRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_ECO5E
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M2_I56A3
Sequence: MSLLTEVETPIKSGWECRCNDSSDLLVAIASITGILHLILWIFDRLFFKCAYRRFRHGLKRGPSTGGIPESMREEYRQEQQSDVNVDNGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: MUTS_BRUSI
Sequence: MEAKVEEKEPEPVENAGPDAPVRLTPMMEQYIEIKAANVDSLLFYRMGDFYELFFDDAVAASAALGITLTKRGKHLGEDIPMCGVPVHAADDYLQKLIAKGYRVAVCEQVEDPAEAKKRGSKSVVKRDVIRLVTPGTLTEEKLLDPAQANFLMAMGRTRGDGALALAWIDISTGTFRVAETTPDRLFADIMRVDPRELVVADSAFHDEELRPVFDLIGKAVTPQPATLFDSAAAQTRIQHYFNVATLDGFGQFSRPELSAISGAIAYIEKTQISERPPLMRPEREHEGGTLFIDPATRASLELARTMSGNRDGSLLKAIDRTVTGGGARLLAERLTAPLTSPKEIALRLDSVSWCLSEQTLCEALRLELKGVPDMPRALSRLAVGRGGPRDLGALACGFEAAGGIASLLDGALLPDELAAARESIEKMPAGFAAHLDRALADELPLLKRDGGFVREGYNSELDEMRALRDQSRRVIAGLQADYIEETGIKSLKIKHNNVLGYFIEVTANNSGAMTDTDEAKSRFIHRQTMANAMRFTTTELAELESKIANAADRALSIELAIFEELTAEAVAHADSIRAAASALSVFDVSTALAVLAEEQGYCRPHVDDSLSFNIVAGRHPVVEQALRRQAANPFVANDCDLSPQRDGGDGAIWLLTGPNMGGKSTFLRQNALIAILAQMGSFVPAGSAHIGVVDRLFSRVGASDDLARGRSTFMVEMVETAAILNQAGEHSLVILDEIGRGTATFDGLSIAWAAVEYLHEKNRCRALFATHFHEMTALSEKLERLSNVTMRVKEWDNDVIFLHEVAKGAADRSYGVQVARLAGLPEAVVNRARDVLHQLEAGETSGKADRLIDDLPLFSVMLQQEKPKPQIQAKDSELANAVAAISPDELTPREALDLIYKLKELAGKA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: HVT1_ARATH
Sequence: MGNKRFRSDNNAGKPTSVEATRIWATKVIEDFRASGNEVYTFEHNLSNNERGVIHQMCRKMGIQSKSSGRGEQRRLSIFKSRHKNGNKNEANEKSNKEKLKCVSFPPGADVILQELFTHYPPCDGDTAATSFTKYSGNKGKQGQWKDDFFRKPQISSEEILEKVASLSSRLKKDKALKEITKLRSKLPITSFKDAITSAVESNQVILISGETGCGKTTQVPQYLLDHMWSSKRETCKIVCTQPRRISAMSVSERISCERGESIGENIGYKVRLQSKGGRHSSVVFCTNGILLRVLVGKGSVSSVSDITHIIVDEIHERDCYSDFMLAIIRDLLPSNPHLRLILMSATLDAERFSGYFGGCPVVRVPGFTYPVRTLYLEDVLSILKSGGDNHLSSTNLSISDHKLDLTDEDKLALDEAIILAWTNDEFDALLDLVSSRGSHEIYNYQHQSTWLTPLMVFAGKGRISDVCMLLSFGADWSLKSKDGMTALELAEAENQLEAAQIIREHADNSQSNSQQGQQLLDKYMATINPEQVDVSLIQQLMRKICGDSEDGAILVFLPGWDDINKTRQRLLENPFFADSAKFDIICLHSMVPAGEQKKVFNRPPPGCRKIVLATNIAESAVTIDDVVYVIDSGRMKEKSYDPYNNVSTLQSSWVSKANAKQRQGRAGRCQPGICYHLYSRLRAASMPDFKVPEIKRMPVEELCLQVKILDPNCKTNDFLQKLLDPPVDQSIANALSILQDIGALTPQEELTELGEKFGHLPVHPLISKMLFFAVLVNCLDPALTLACAADYKEPFTMPMSPVERQKAAAAKLELASLCGGDSDHLAVVAAFECWKNAKGRGLSAEFCSQYFVSPSAMKMLDQMRSQLESELKRHGIIPNDISSCSQNSRDPGILRAVLAVGLYPMVGRLCPAFGNNRRTIVETASGAKVRVHSLSNNFNLSSKKYDESLLVFDEITRGDGGMHIRNCTVARDLPLLLISTEIAVAPTGSSDSDDSNEEEEDDEEVAANTNEEVAANTNEEGMDIHKEESRRGAKMMSSPENSVKLVVDRWLPFRTTALEVAQMYILRERLMASILFKVTHPREHLPPHLGASMHAIAGILSYDGHAGLSCPPESMVPKHSRTEMYDTGGWEEKPNSFLNSLFWSLSLKENKHPSHTNRNQQHNYNMAPTEAASIPRQQNYKQRNPKATNNTDSGKKKEKMFVNPTNRINQPEAASTGKPSKHKSANSSGSSNKKENMPSDQAYGNKQHNTVPREAAAPMAKNQSSKKTKTRSGNNSDSGKKKEQYIPKRQREDKAEQK
What is the function of this protein?
May function as an ATP-dependent RNA/DNA helicase.
What are the official names of this protein?
DExH-box ATP-dependent RNA helicase DExH6, Protein HELICASE IN VASCULAR TISSUE AND TAPETUM.
What is the protein family that this protein belongs to?
Belongs to the DExH box helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SERA_ENTH1
Sequence: MFAFLLFIAFTSATNIILDLDQEVKDTNIYGVFLKNEASPEKLEEAEEKEKSSSAKPESSSNEDNEDDEDEKASSSDNSESSSSDKPDNKPEASSSDKPEASSSDKPDNKPEASSSDKPDNKPEASSSDKPDNKPEASSSDKPDNKPEASSSDKPDNKPEASSTNKPEASSTNKPEASSTNKPEASSTNKPEASSTSNSNDKSGSSSDNDNNNLDAASSPFIVFCAIIIAIIF
What is the function of this protein?
Plays a role in the adhesion to host cells (PubMed:1695007).  Involved in the adhesion to host apoptotic cells thereby facilitating their phagocytosis (PubMed:18086807).
What are the official names of this protein?
Serine-rich 25 kDa antigen protein.
Protein: SPI1_MONPV
Sequence: MDIFKELILKHTDENVLISPVSILSTLSILNHGAAGSTAEQLSKYIENMNENTPDDKKDDNNDMDVDIPYCATLATANKIYGSDSIEFHASFLQKIKDDFQTVNFNNANQTKELINEWVKTMTNGKINSLLTSPLSINTRMIVISAVHFKAMWKYPFSKHLTYTDKFYISKNIVTSVDMMVGTENDLQYVHINELFGGFSIIDIPYEGNSSMVIILPDDIEGIYNIEKNITDEKFKKWCGMLSTKSIDLYMPKFKVEMTEPYNLVPILENLGLTNIFGYYADFSKMCNETITVEKFLHTTFIDVNEEYTEVSAVTGVFMTNFSMVYRMKVYINHPFIYMIKDNTGHTLFIGKYCYPQ
What is the function of this protein?
Plays a role in mediating viral host range.  May act to inhibit a caspase independent form of apoptosis to allow efficient virus replication in infected cells.
What are the official names of this protein?
Serine proteinase inhibitor 1, Serp-1, Serpin-1.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Poxviruses subfamily.
Protein: SARS_STAAE
Sequence: MKYNNHDKIRDFIIIEAYMFRFKKKVKPEVDMTIKEFILLTYLFHQQENTLPFKKIVSDLCYKQSDLVQHIKVLVKHSYISKVRSKIDERNTYISISEEQREKIAERVTLFDQIIKQFNLADQSESQMIPKDSKEFLNLMMYTMYFKNIIKKHLTLSFVEFTILAIITSQNKNIVLLKDLIETIHHKYPQTVRALNNLKKQGYLIKERSTEDERKILIHMDDAQQDHAEQLLAQVNQLLADKDHLHLVFE
What is the function of this protein?
Transcriptional regulator that controls expression of some virulence factors in a cell density-dependent manner.
What are the official names of this protein?
HTH-type transcriptional regulator SarS, Staphylococcal accessory regulator S.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBD_PLETE
Sequence: MTIAIGKPEEKTSWFDKVDDWVRRDRFVFVGWSGLLLFPTAYLALGGWLTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLGHSLLLLWGPEAQGDLTRWFQLGGLWTFVALHGAFALIGFMLRQFEIARSVKLRPYNAIAFSAPISVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHEKLVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ISPG_ECO55
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: MIRH1_HUMAN
Sequence: MFCHVDVKISSKRYTWTKLPLNVPKLVLIYLQSHFVLFFFSMCQSIWERPAIGRATTSSASWMVGYDCLL
What are the official names of this protein?
Putative microRNA 17 host gene protein, Putative microRNA host gene 1 protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PYRG_PROM4
Sequence: MPKFVFVTGGVVSSIGKGIVAASLGRLLKSRGYNVSILKLDPYLNVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTALSRLNSVTTGSIYQSVINKERRGDYDGGTVQVIPHITQEIRERIHRVGANSNADVVITEIGGTVGDIESLPFLEAIREFKGDVGKKDIAYIHVTLLPFIGTSGELKTKPTQHSVKELRSIGIQPDLLICRSDRPINDNLKNKISGFCGVNNEAVIPALDADSIYSVPLALKAEGLCKEVLEFLDLTDHECNLEKWQELVHKLRNPGPSVKVAVVGKYVQLNDAYLSVVEALRHACIENDASLDLHWICAEKIEEEGSNDLLTGMDAIVVPGGFGSRGVDGKIAAIQWAREQRVPFLGLCLGMQCAVIEWARNLAGLKEATSFELDQSTPHPVIHLLPEQQDVVDLGGTMRLGVYPCRLQAETMGQKLYGEQVVYERHRHRYEFNNAYRNLFIESGYTISGTSPDGRLVELIELKGHPFFTACQYHPEFLSRPGKPHPLFKGLIAAAQSRLPRSPQEALKQTQINSPNQSKNNP
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.