PharMolix/UniProtQA huggingface dataset:
Protein: RL25_TROW8
Sequence: MVYPVVEAESRVGFGKGFARRARAAGKIPAVAYGLKRAPEHVLLPAAQMSLIMRRANALLQLKIDARESLVLIKQVQRDRIRNIIEHLDMLFVNEDDAVTIRVPLRFVGQSYAGTVTSVENYSVAVTLQVSQIPEALVVDVSGLQAGRRIFASDIALPDGALLVSPPRLLIAKVDPVRRATQEPPPD
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: Y655_ARCFU
Sequence: MRFWDIRRVENVSLNLQLENGKLEKPRYNKSTSKGFRVLKNGFWGIFEGNVADDEGLRQAEKNAFTQGDGDIEEIATKGRYRMRVKRDPQDMSIEEKVELLKDLEKIIRDVCVSTKLVYFENRRVLQYRDSCGSEVEYEVLRTGVSIMGVGKGRSLQFLSKRQMRVGGYEVLDGVDEKAYEIVEVLPKLVNALAPPSGEMSVVMDSSLAGVFVHEAFGHAVEADHVLQGATVLKGRLNEKVADESVTIIDDPTLPEFGFFPFDDEGVRAEKKVIVEDGVLKSFLHSRETAKKLGGVAGNARSQGVDVPIVRMSNTYIDTHHYSFDELLEECRDGVYLVGSRGGETNPATGYFHFNAQYGYLIKNGELAEMVRDVSLSGNTLEILRNVKIGREIEFDPGFCGKAGQLVPVSDGSPPVLCRATVGGA
What is the function of this protein?
Probable metalloprotease.
What are the official names of this protein?
Metalloprotease AF_0655.
What is the protein family that this protein belongs to?
Belongs to the peptidase U62 family.
Protein: NDOR1_CRYNJ
Sequence: MIPMILYASETGNAQDTAERVARAFRANGRAVTCLPMDQFPISALPHTYLLILLTSTHGRGDPPPAMLPLWTALLRSSLPEDILEDVHFALFGLGDSSYERFCYAGKMLLRRMEQLGATKMGEPAWGDERSPNGIEDAFLPWLQQTLDLYLPYLPLISPTPKIIESTVLPPPIYKISPASTSKSVEHDLSLERLSISFPIPNGKPAPVRVEDQARDKASTSRTKPDDWVWATLKKNIRLTSKDWWQDVREIELEFDDPDTKPYTAGSICSLQPQSREDDVNMFLEMMELTSQADEVVTIESLLDEQPLPSHLPPAGTPTTLRSLLTNHLDIRYSPRKSFFEWLRRLSTNEMERERLDEFISDPDEIHTYATRPSRTIVETLADFRFTRIPMSHILEILPPLRRRQFSIASSWEDHPGKVQLLVALIEYKTNLKIPRKGLCSSWLNGLPVGTRIPIHIASPTLFLPQDPEVPIILVGPGTGVAPMRAFVEIRVRQGAAKNTSLYFGCRSSTTDYFFESEWDVHREKGVKIQVAASRDQEERIYVQHLIKRDKEYVKEWIVDKKGWLFISGSSNAMPREVREAVAWCISKEGAGDMTEEESKAYVEQMFEDKRGGEESW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.  Positively controls H(2)O(2)-induced cell death.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Protein: MILK1_MOUSE
Sequence: MAGPRGALLAWCRRQCEGYRGVDIRDLSSSFRDGLAFCAILHRHRPDLLDFQSLSKENVFENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFTSSGQAAASPPKPGKDPAPPSPTSTSPAVQPGEEAQGDDLSPDSLSEQGKQQPPSSACAACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLVPGSYSSGPEEGTFVCAERCTRLGPGSRSGTRLLSQQRQQPAAAEAKDAEDNDPSLSVAAVAEADRLQASSEVQFHTPTKPPLPSKPQELASPPGGRPTPAPRKASESSALTPPTPRPRSSLQQDGTVEQSVSSGLVNGRLQEPPVPKPRGTPKLSERMAAPRKDPPWITLVQTEPKKKPAPQPPSSGPGPLSQAYRQVEDGGLEEQTQKSSGTEPEPKPYNPFEEEEEEEGEPAPPVPSPSLAPPVPSPSPAPPVPSPAPAPSEATPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLAIHASRLSHSEPPSATPSPALSVESLSSESSSHTANAEPLEPPAVPKSSSDPAVHVPGTPGTSGNSVTPSANSSLSSSGELGQPSGEQMLQARTKGSAGTHSTKPFSGATPTPFLLAGDRNPAPPVGSASPQLQIKSSCKENPFNRKPSPSASPTVRKATKGAKPVRPPAPGHGFPLIKRKVQADQYIPEEDIYGEMDNIERQLDALEHSGVLLEEKLRGGANEGSEDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEFELRCLLNKPEKDWTDEDRAREKVLMQELMTLIEQRDAIVNCLDEDRQREEEEDKMLETMIKKKDFQREAESDSKKKGKFKTIKVLKFLGNKREAKSKAPGDKS
What is the function of this protein?
Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes.  On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation.  May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking.  Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane.  May indirectly play a role in neurite outgrowth.
What are the official names of this protein?
MICAL-like protein 1, Molecule interacting with Rab13, MIRab13.
What are the subcellular locations of this protein?
Recycling endosome membrane; Peripheral membrane protein. Late endosome membrane. Note=Localization to late endosomes is actin-dependent. Association to tubular recycling endosomes is regulated by RAB35 and ARF6 (By similarity).
Protein: MEP20_ASPFL
Sequence: MRFTALASAILPLACNVLALPAKTGEAPKLDVSLSQVDNTLIKAVVKNTGSEDITFVHLNFFRDKAPVKKVSLFRQRYVIPLHPHFPALTSVIQPTELPFQGIKQRFRTEGLTEDALTVLAPGESIEDEFDIAATSDLSEGGSITISTDGFVPIATGNKITGSVPYSSNELSIEVDAAQAASVASAVKPLDKRTKVASCSGTRSSALSTALKNTVSLANQAASAAQSGSSSRFQEYFKTTSSSVRTSVAARFRAVASEASSTSSGSTTYYCTDTYGYCSSNVPGVHLPAYNIIANCDIYYTYLSALTRTCHAQDQATTTLHEFTHAPGVYSPGTDDLGYGYDAATALSSSQALNNVDTYALFANGKFLLSREVDVKYLHTT
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog mep20, Deuterolysin mep20.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
Protein: GCST_NOSS1
Sequence: MANQKDTAETLARTPLYQLGVELKARLTSFGGWEMPVQFSGITREHEAVRNAAGMFDISHMGKFTLQGKNLISQLQGLVPSDLSRLQPGQAQYTVLLNPQGGIIDDIIVYYQGEDNTGTQQAFIIVNAATTSKDKAWILSHLDQNQVQFQDISPAKVLIAIQGPKAIGYLQPFVQQNLQPIKAFGHLEATVLGQAGFIARTGYTGEDGFEILVDPEVGVELWRSLYDAGVIPCGLGARDTLRLEAAMALYGQDIDDNTTPLEAGLGWLVHLDTKGDFIGRSVLEQQKATGVQRRLIGLQTQGRNIARHGYQVLSDGKVVGGVTSGTLSPTLGYPVALAYVPSKLAKVGQPLEVEIRGKAYPAVVVKRPFYRSSNKG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: PA2H_BOTPA
Sequence: SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGQPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKADPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that lacks enzymatic activity (PubMed:10860537).  Is myotoxic and displays edema-inducing activity (PubMed:10860537, PubMed:9972319).  Displays bactericidal activity and promotes the blockage of the neuromuscular contraction of the chick biventer cervicis muscle (PubMed:10860537, PubMed:9972319).  Also disrupts artificial membranes, and provokes tissue damages characterized by edema, necrosis and inflammation (PubMed:10860537, PubMed:9972319).  May act as pro-inflammatory mediators, inducing metalloproteinase and cytokine production from the inflammatory and satellite cells (PubMed:19673103).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog BnSP-7, svPLA2 homolog, Phospholipase A2 II.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOB_SYNE7
Sequence: MEAIRHDWTLEEIEDLLNTPLLELVHRAQTVHRDYQPANAIQLATLLSVKTGGCSENCAYCPQSAHYNTEVDPQSTLPIETVLEQAERAKAAGASRFCMGWAWREIRDGAQFDAMLEMVQGVRQLGLEACVTAGMLSDRQAERLAEAGLTAYNHNLDTSPEFYGEIISTRTYADRLATLERVRQAGISVCCGGIIGMGEGQRDRAGLLQVLATLNPHPESVPINALVPVEGTPLGDRDRLDPLDLVRMCAVARILMPKARVRLSAGRTALSREAQVLCFLAGANSIFYGDTLLTTANPVCEADRQLLADIGAEALEVVTA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: DNAA_CUTAK
Sequence: MSDTPFGDADHPRPAPIHPDAVLPPPMSSQSADNDPTEALNEAWTNILTKVSKPNRAWLSNTTPVTMHSSTAMVAVPNEFARDRLESKMRYELEELLSDHFHKAIHLAITIDPDLELALGAPDHEDEEEEVPPAQFVPKVTVGVTEPSARPTTTIDDDEGNRLNPKYTFDSFVIGASNRFAHAAAVAVAEAPGKSYNPLLIYGGSGLGKTHLLHAIGRYVMSYYDNVKVKYVSTEELTNDFINAIGTNRTTEFRRSYRDVDVLLVDDIQFLQSKIQTQEEFFHTFNTLHNAQKQIVMTSDRPPKLLEALEPRLRSRFEWGLLTDIQPPDLETRIAILRRKVAAEKITVEPDVLEFIASRIQTNIRELEGALIRVTAFASLNQQPVDISLAEVVLKDLIPEGRETPVTPERIIAETADYFDISADDLLGTSRAQTLVTARQIAMYLCRELTDLSLPKIGAEFGGKDHTTVMHADRKIRALMGEQRQIFNQVSEITNRIKQY
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGGT_WHEAT
Sequence: MQATTAAAAAQLLTDTRRGPRCSRARLGATRLSWPGRFAVEAFAGRCQSSATTVTHRFSAISQATSPRRKARRQCSDDQSALQAGCSKVNRDQHGYDVNWFEEISQEVSKKLRAFYQFCRPHTIFGTIIGITSVSLLPMKSIDDFTATVLKGYLEALAAALCMNIYVVGLNQLYDIQIDKINKPGLPLAAGEFSVATGVFLVVTFLIMSFSIGIHSGSVPLMYALVVSFLLGSAYSIEAPLLRWKRHALLAASCILFVRAILVQLAFFAHMQQHVLKRPLAATKSLVFATLFMCCFSAVIALFKDIPDVDGDRDFGIQSLSVRLGPQRVYQLCISILLTAYLAATVVGASSTHLLQKIITVSGHGLLALTLWQRARHLEVENQARVTSFYMFIWKLFYAEYFLIPFVQ
What is the function of this protein?
Involved in the synthesis of tocotrienol (vitamin E).  Catalyzes the condensation of homogentisate and geranylgeranyl diphosphate to form 2-methyl-6-geranylgeranylbenzoquinol.  Possesses low activity with phytyl diphosphate as substrate.
What are the official names of this protein?
Homogentisate geranylgeranyltransferase, HGGT.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: EFTS_PELPB
Sequence: MSQISAKDVKNLRDITGAGMMDCKKALDETGGDMQQAIDYLRKKGAALAAKRADRDAREGMVEIKMTADHKAGIILELNCETDFVARGEDFTNFTVALGELALAKCISSPEALMTLTLGEAYGGETVDDAIKTMTGKLGEKISLKRLVYIDAGDGVVESYVHPGAQLGAIIHLATDQPDAVRELARDLAMQVAAAAPIVVDRSFVPADYIAKEAEIYRQQALEQGKKEAFVDKIVLGRLEKYYQDVVLSEQFFIKDSTVKVSDVLNEFRKKHQVKVDVIGFVRCKLGE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_STRZT
Sequence: MDTQKIEAAVKMIIEAVGENVNREGLQETPARVARMYQEIFSGLGQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKLARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATLTTVARGLFETDKDLRDQAYRLMGL
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: NRFA_SALTY
Sequence: MARKTLRARRFFSLIFPFFFITSVYAEQTPESAKTVTVEAKNEMFAPQHPDQYQSWKATSEQSAREDALAEDPRLVILWAGYPFSRDYNKPRGHAYAVTDVRETLRTGAPKTAEDGPLPMACWSCKSPDVARLIQQEGEDGYFHGKWARGGPEIVNDLGCADCHNTASDDFAQGKPALTLSRPYAERAMEAIGKPFDKAGRFDQQSMVCGQCHVEYYFDGKNKAVKFPWDEGMKVENMEQYYDTIAFSDWTNSLSKTPMLKAQHPEYETWSAGIHGKNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKASLQKVVAERKQAIHDLKIKVEDQLVHAHFEAKAAWDAGATDAEMKPILNDIRHAQWRWDLAIASHGIHMHAPEEGLRMLGSAMDKAADARTKLARLLATKGITHEIPLPDISTKEKAQKAIGLNMQQINAEKQDFLKTVVPQWEDQARKNGLLSQ
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RH6_ORYSJ
Sequence: MDPRARYPPGIGNGRGGNPNYYGRGPPPSQHQQHQHQHQQPPHPHHHQYVQRQPQPQQTPHNSQHQQWLRRNQIAAEAAGASEQKAPPVADGIDSSSQDWKAQLKLPPQDTRYRTEDVTATKGNEFEDYFLKRELLMGIYEKGFERPSPIQEESIPIALTGSDILARAKNGTGKTAAFCIPALEKIDQDKNAIQVVILVPTRELALQTSQVCKELGKHLKIQVMVTTGGTSLKDDIVRLYQPVHLLVGTPGRILDLTKKGVCVLKNCSMLVMDEADKLLSPEFQPSIQELIRYLPSNRQILMFSATFPVTVKEFKDKYLPKPYVINLMDELTLKGITQFYAFVEERQKVHCLNTLFSKLQINQSIIFCNSVNRVELLAKKITELGYSCFYIHAKMLQDHRNRVFHDFRNGACRNLVCTDLFTRGIDIQAVNVVINFDFPKSAETYLHRVGRSGRFGHLGLAVNLITYEDRFNLYRIEQELGTEIKPIPPQIDRAIYCQ
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 6.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: SEPF_MACCJ
Sequence: MAFKDVFKGFFAYEDEEVYVEEQSDKVREPAQKKVVKETYVPEKKVVRTESFQKQSKPKMKVNEEKVTKANVVNMHDDIVNVSSKVCLFEPRVFSDTQDIADELKNRRATLVNLQRIDKISAKRIIDFLSGTVYAIGGDIQRIGQDIFLCTPDNVEVAGTITEMLEAPEEENE
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: LPXA_CAUVN
Sequence: MSIHPTAIIAPEAKLAPDVEVGPFSIVGPDVTLAAGVRLLSHVVVEGATTIGEGCVVHSFANLGGPPQHLGHKGERTELIIGPRNIIREHVTMHTGTASGKGVTTIGSDGLYMVGSHVAHDCTVGDFVVLAKGATLGGHVAIGDYVFMGGLAAAHQFSRIGRYSFIGGLAAVTKDVIPYGSVWGNHAHLEGLNLVGLKRRGFPRETINALRAAYRLMFADEGTFQERLDDVAEIHAGNAEVMEIVDFIRTDANRPLCLPEREV
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROPB_RHILV
Sequence: MRVLIAGLMASVFAIAGVSAAQAADRVDQVPEAPVAQEAPVKPAGSWEGFYLGGAGTYNMGDFGSDRHTYGFGGQVFTGYNWQQGQIVYGVESDLGYSGDDVSSGGVENKYGWNGSVRGRVGYDMNPFLLYGTAGLAIGDVKVSDDTSDESKTNFGYTVGAGVEAFVTNNITTRLEYRYTDYQSKDYDLDSGSFSRGYDENSVKLGIGVKF
What are the official names of this protein?
22 kDa outer membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Omp25/RopB family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: SETD6_RAT
Sequence: MAAPAKRARVSDASPLAAPCPVPRAAARVPLPLPAGPSGHEPESDAVAGFLRWCTRVGLELSPKVLVSRQGTVAGYGMVARESVQPGELLFAVPRSALLSPHTCSISDLLERERGALQSLSGWVPLLLALLHELQAPASPWSPYFALWPELGRLEHPMFWPEEERLRLLKGTGVPEAVEKDLVNIRSEYYSIVLPFMEAHSDLFSPTVRSLELYRQLVALVMAYSFQEPLEEEEDEKEPNSPLMVPAADILNHIANHNANLEYSAEYLRMVATQPILKGHEIFNTYGQMANWQLIHMYGFAEPYPNNTDDTADIQMVAVREAALQGTEDETERLLLCERWDFLCKQELVGEEGAFVIGREEVLTEEELATTLKVLCMPAEEFRDYKERAGWGEEETEDGSLAITNIPKLQESWKRLLRDSVLLTLQTYATDLKTEQDLLSNKEVYAKLSWREQQALQVRYGQKMILHRLLELTS
What is the function of this protein?
Protein-lysine N-methyltransferase.  Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulation of NF-kappa-B transcription factor activity.  Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (By similarity).  Required for the maintenance of embryonic stem cell self-renewal (By similarity).  Methylates PAK4.
What are the official names of this protein?
N-lysine methyltransferase SETD6, SET domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RK20_LOTJA
Sequence: MTRIKRGYIARKRRTKIRLFTSSFRGAHSRLTRTISQQKIKALVSAHRDRNRKKREFRGLWISRINAGIGDNDKKKNIYYSYSNFMYNLYKKQLLLNRKIVAQIAIFKGNCLFMIANEIIT
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYB_BUBDE
Sequence: MTNIRKSHPLMKILNNAFIDLPAPSNISSWWNLGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGMYYGSYTFLETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGISSDTDKIPFHPYYTIKDILGALLLILALMLLVLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILILMPLLHTSKQRSMMFRPFSQCLFWILVANLLTLTWIGGQPVEHPYIIIGQLASVTYFLLILVLMPTASMIENSLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARGB_SALA4
Sequence: MNPLIIKLGGVLLDSEEALERLFTALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKDGLRVTPADQIGIITGALAGTANKTLLAWAKKHHIASVGLFLGDGDSVNVTQLDEALGHVGLAQPGSPKLINMLLENGFLPVVSSIGVTEDGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTASKAEQLIDQGIITDGMIVKVNAALDAARALGRPVDIASWRHAEQLPALFNGTPIGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_METM5
Sequence: MAILKASEIRELSAEEMKGKIAELKRELMKEGVNKSTGGAPSNPGKISEIKRTIARILTIMNEKEAQAKNA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CTL2_CAVPO
Sequence: MEDQRKYGAYGTPQKYDPTFKGPIYNRGCTDVLCCVLLFLAIVGYVAVGLIAWTHGDPRKVIYPTDSRGEFCGQKGTKNANKPFLFYFNIVKCASPLVLLEFQCPTPQICVEKCPNRYLTLLNAWNTPEFEYYKQFCVPDFQKNKKGVAQVLRDGQCPAVLIPSKPLAQRCFPDIHAHKGVIMVGNATTYEDGHGSRKNITELVEGAKQANGILEARQLAMRIFEDYTVSWYWIVIGLVIAMVLSLLFIILLRFLAGIMVWVMIVLVILVLGYGIFHCYMEYARLRGEAGSDISVLDLGFQTDFRVYLHLRQTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCSLLYPLVTFFLLCLCIAYWASTAVFLSTSNEAVYKILGDSSCPHQGQTCHPETFFNSTEAHACPNARCQFAFYGGESGYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWALRKPDDMPAFPLFAAFGRALRYHTGSLAFGSLILAIVQIIRVILEYLDQRLKAAENKFAKFLMTCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRIRIVQDTAPPLNYYWVPILTVIVGSYLIAHGFFSVYGMCVDTLFLCFLEDLERNNGSSERPYFMSSTLKKLLNKTNKKPVES
What is the function of this protein?
Choline transporter (By similarity).  Essential for hair cell survival.
What are the official names of this protein?
Choline transporter-like protein 2, Inner ear supporting cell antigen, IESCA, Solute carrier family 44 member 2.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: XERC_LEPIC
Sequence: MGDYPFQFPEFSSESLNETAKKFINYLKIEKNYSQNTINAYSIDLKFFFEFCEKEQLDIFQIEPVDIRSYFAYLAKKHEIDRRSQSRKLSSLRTFYKVLLREDLVKSNPATQLSFPKVRKEVPKNFRINETEEILEFESENASEVSEIRDRAMIEVLYSSGLRVFELVNAKLNSLSKDLTVLKVLGKGRKERFVYFGKEAVSSLQKYLEYRNVSFPDAEEIFLNQRGKKLTTRGVRYILNERRKKMGWEKTITPHKFRHTFATDLLDAGAEIRAVQELLGHSSLSTTQIYLSVSKEKIKEVYRKAHPHARK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.