PharMolix/UniProtQA huggingface dataset:
Protein: LUXS_MARMS
Sequence: MPLLDSFRVDHTRMDAPAVRVAKSMSTPKGDDITVFDLRFCVPNEEILSEKGIHTLEHLFAGFMRDHLNSNNVEIIDISPMGCRTGFYMSLIGTPSEETVAASWKAAMEDVLKVKAKSDIPELNEYQCGTYEMHSLEEAQEIAKMILDRDVKVNSNEELYLSEEFLKEHS
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RPOA_CLOD6
Sequence: MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRILLSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQGPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVPIGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLVEHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEELANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: NDF1_XENLA
Sequence: MTKSYGENGLILAETPGCRGWVDECLSSQDENDLEKKEGELMKEDDEDSLNHHNGEENEEEDEGDEEEEDDEDDDEDDDQKPKRRGPKKKKMTKARVERFKVRRMKANARERNRMHGLNDALDSLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPTTNLVAGCLQLNPRTFLPEQSQDIQSHMQTASSSFPLQGYPYQSPGLPSPPYGTMDSSHVFHVKPHSYGAALEPFFDSSTVTECTSPSFDGPLSPPLSVNGNFTFKHEHSEYDKNYTFTMHYPAATISQGHGPLFSTGGPRCEIPIDTIMSYDGHSHHERVMSAQLNAIFHD
What is the function of this protein?
Acts as a transcriptional activator.  Plays a role as a differentiation factor during neurogenesis.  Required for the conversion of cells within the neural plate and ventral ectoderm into differentiated neurons.  Promotes the differentiation of late-born retinal amacrine cells, but not early-born retinal ganglion cells.  Its function is inhibited at early stages of retinal cells differentiation.
What are the official names of this protein?
Neurogenic differentiation factor 1, NeuroD1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BETI_VIBVY
Sequence: MPKVGMPKIRRPQLVSATMTVIDRVGLHGASVSLISQEAGVSSGIINHYFGGKHGLLEETMRDILRQLSCDATKRLNSLPKQAHMQRINAILDANFVGFQSESKVIKTWLAFWSYSMHDEALKRLQRVNEKRLLSHLKRELKALMSKEQADIVAQGIAALIDGIWLRGALNPEGINANKARIIINDYLEKQLTFYSQQ
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: KCNS1_CHLAE
Sequence: MLMLLVRGTHYESLRSKVVLPTPLGGRGTEALVSECPSPDTGIRWRQSDEALRVNVGGVRRLLSARALARFPGTRLGRLQAAASEEQARRLCDDYDAAAREFYFDRHPGFFLGLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRLSQPRAWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGGTGGKELGHLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKEEDVGFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVRNSNHQEFEDLLSSVDGVSEASLETSRETSQEGRSADLETQAPSEPPHPQMY
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.
What are the official names of this protein?
Potassium voltage-gated channel subfamily S member 1, Delayed-rectifier K(+) channel alpha subunit 1, Voltage-gated potassium channel subunit Kv9.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2.
Protein: THIQ_SHISS
Sequence: MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGSLTIDSVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAAQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTDELLSGKASASALLGITG
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NADK_STAAE
Sequence: MRYTILTKGDSKSNALKHKMMNYMKDFRMIEDSENPEIVISVGGDGTLLQAFHQYSHMLSKVAFVGVHTGHLGFYADWLPHEVEKLIIEINNSEFQVIEYPLLEIIMRYNDNGYETRYLALNEATMKTENGSTLVVDVNLRGKHFERFRGDGLCVSTPSGSTAYNKALGGALIHPSLEAMQITEIASINNRVFRTVGSPLVLPKHHTCLISPVNHDTIRMTIDHVSIKHKNVNSIQYRVANEKVRFARFRPFPFWKRVHDSFISSDEER
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_STRTD
Sequence: MSTYAIIKTGGKQVKVEVGQAIYVEKINAEAGSEVTFNEVVLVGGDKTVVGTPVVEGATVVGTIEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GLMM_STRPC
Sequence: MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIIFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: UBL5_ARATH
Sequence: MIEVVLNDRLGKKVRVKCNDDDTIGDLKKLVAAQTGTRAEKIRIQKWYNIYKDHITLKDYEIHDGMGLELYYN
What are the official names of this protein?
Ubiquitin-like protein 5.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_GEMAT
Sequence: MGEVRRPDRVAEAIREEVATFLSEGAKDPRIRAFVTVTAVEVTRDLRHATVFVSLMGDDADKKSTTAGLASVASHLRSQLGKSLRLRSAPEIHFRTDESVARASRIEHLLAKIRDEREAQEPAQDPAQDSSQDASVEASDAPDKAE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATRX_MUMPS
Sequence: MAGSQIKIPLPKPPDSDSQRLNAFPVIMAQEGKGRLLRQIRLRKILSGDPSDQQITFVNTYGFIRATPETSEFISESSQQEVTPVVTACMLSFGAGPVLEDPQHMLKALDQTDIRVRKTASDKEQILFEINRIPNLFRHHQISADHLIQASSDKYVKSPAKLIAGVNYIYCVTFLSVTVCSASLKFRVARPLLAARSRLVRAVQMEVLLRVTCKKDSQMAKSMLNDPDGEGCIASVWFHLCNLCKGRNKLRSYDENYFASKCRKMNLTVSIGDMWGPTILVHAGGHIPTTAKPFFNSRGWVCHPIHQSSPSLAKTLWSSGCEIKAASAILQGSDYASLAKTDDIIYSKIKVDKDAANYKGVSWSPFRKSASMSNL
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: AROE_CHLCH
Sequence: MNSSTRIFALLGRAVDYSYSPLIHNTAFQALGLPYHYTIFNIAEAALVGDALRGARALGLGGFSVTIPYKQTVVPFLDELSEEATTIQAVNCIVNKNGKLIGYNTDILGFASPLFAYREALHGATIALFGSGGAALAAIEAFQRYFTPKQVLLFARDSQKAKSQLRSSLALERYTNLAIVPLSDYERVRECRLVINATPLGTKGRADGSAIIPLESNLLHSEHIVYDMVYNPTITPLLQAAQAVGASTIFGIEMLIGQAEQAFTLWTGEKMPTELVRQTVMAKLQEL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: PLCA_SHEEP
Sequence: MELWPGAGTLLLLLFLLLLLLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVRGRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLPGHCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGRCQVRVLPPVPTEGLKPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGVGEAGL
What is the function of this protein?
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha, 1-acylglycerol-3-phosphate O-acyltransferase 1, 1-AGP acyltransferase 1, 1-AGPAT 1, Lysophosphatidic acid acyltransferase alpha, LPAAT-alpha.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MNME_THET8
Sequence: MNLKDPICAIATPPGKGAIGVVRLSGEGALEIAARVWRGKDPRRLKGGRFALGEVVDPKTGEAIDQAILLVFRAPRSYTGEDLVEFQTHGSPAVLRRVMEVLVAEGARPAGRGEFTFRAYLNGKMDLAQAEAVLALIEAEGELARRQALRALEGALSRRIEALENRLLNLLAHIQALLDYPEEGVEPLEAERTIREVLAEVEALLAQAKASRLAQKGARLALIGAPNAGKSSLLNALLGYERALVSPIPGTTRDYLEAPLELFGIPLVAVDTAGVRETEDPVERMGVERALGIAEEADLVLYVVDRSQPKPAPPPLPWARTLKVATKSDLPPAWEDPEFLPVSSLTGEGLDRLKEAVREALLGREGGEVLLTERQVEALLRARERLEEALSLPEDLMGLALEEAARALALLTGKEVAEEVVARVFQNFCVGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRE_RABIT
Sequence: MAQWDSFTDQQEDTDSCSESVKFDARSNTALLPPNPKNGPPLQEKLKSFKAALIALYLLVFAVLIPIIAIMAAQLLKWEMKNCTVGSINANSVSSSLLGRGNDSEHEVRFREVVMEHISKMEKRIQYISDTEENLVDSEHFQNFSVTTDQRFADVLLQLSTLVPTVQGHGNAVDEITRSLISLNTTLLDLHLYVETLNVKFQENTLKGQEEISKLKERVHNASAEIMSMKEEQVHLEQEIKREVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGEKGDRGPTGESGPPGVPGPVGPPGLKGDRGSIGFPGSRGYPGQSGKTGRTGYPGPKGQKGEKGSGSILTPSATVRLVGGRGPHEGRVEILHNGQWGTVCDDHWELRAGQVVCRSLGYRGVKSVHKKAYFGQGTGPIWLNEVPCLGMESSIEECKIRQWGVRVCSHGEDAGVTCTL
What is the function of this protein?
Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis.  Two types of receptor subunits exist.  These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL).
What are the official names of this protein?
Macrophage scavenger receptor types I and II, Macrophage acetylated LDL receptor I and II.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: FMR1N_HUMAN
Sequence: MSSHRRKAKGRNRRSHRAMRVAHLELATYELAATESNPESSHPGYEAAMADRPQPGWRESLKMRVSKPFGMLMLSIWILLFVCYYLSYYLCSGSSYFVLANGHILPNSENAHGQSLEEDSALEALLNFFFPTTCNLRENQVAKPCNELQDLSESECLRHKCCFSSSGTTSFKCFAPFRDVPKQMMQMFGLGAISLILVCLPIYCRSLFWRSEPADDLQRQDNRVVTGLKKQRRKRKRKSEMLQKAARGREEHGDE
What are the official names of this protein?
FMR1 neighbor protein, Cancer/testis antigen 37, CT37, Sarcoma antigen NY-SAR-35.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y256_NITSB
Sequence: MFDKMNLGDLGKVFEEIQERAKKLQEEQESKSFIAKSGGGLIKVTANGKGEIIDIEIDDSLLEDKDSLQILLISAINDVLKMVEEDKQRSALSMMTPDIFGQK
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein NIS_0256.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YACG_NEIGO
Sequence: MAESRQTRLQVKCPTCQTAVVWKPENAFRPFCSQRCKLIDLGGWADGKYTVSGQTESLPEISEPDGAYR
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: PME3_ARATH
Sequence: MAPSMKEIFSKDNFKKNKKLVLLSAAVALLFVAAVAGISAGASKANEKRTLSPSSHAVLRSSCSSTRYPELCISAVVTAGGVELTSQKDVIEASVNLTITAVEHNYFTVKKLIKKRKGLTPREKTALHDCLETIDETLDELHETVEDLHLYPTKKTLREHAGDLKTLISSAITNQETCLDGFSHDDADKQVRKALLKGQIHVEHMCSNALAMIKNMTDTDIANFEQKAKITSNNRKLKEENQETTVAVDIAGAGELDSEGWPTWLSAGDRRLLQGSGVKADATVAADGSGTFKTVAAAVAAAPENSNKRYVIHIKAGVYRENVEVAKKKKNIMFMGDGRTRTIITGSRNVVDGSTTFHSATVAAVGERFLARDITFQNTAGPSKHQAVALRVGSDFSAFYNCDMLAYQDTLYVHSNRQFFVKCLIAGTVDFIFGNAAVVLQDCDIHARRPNSGQKNMVTAQGRTDPNQNTGIVIQKCRIGATSDLQSVKGSFPTYLGRPWKEYSQTVIMQSAISDVIRPEGWSEWTGTFALNTLTYREYSNTGAGAGTANRVKWRGFKVITAAAEAQKYTAGQFIGGGGWLSSTGFPFSLGL
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Pectinesterase/pectinesterase inhibitor 3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Secreted, cell wall.
Protein: DPP4_TRIRU
Sequence: MKLLSLLMLAGIAQAIVPPREPRSPTGGGNKLLTYKECVPRATISPRSTSLAWINSEEDGRYISQSDDGALILQNIVTNTNKTLVAADKVPKGYYDYWFKPDLSAVLWATNYTKQYRHSYFANYFILDIKKGSLTPLAQDQAGDIQYAQWSPMNNSIAYVRXNDLYIWNNGKTKRITENGGPDIFNGVPDWVYEEEIFGDRFALWFSPDGEYLAYLRFNETGVPTYTIPYYKNKQKIAPAYPRELEIRYPKVSAKNPTVQFHLLNIASSQETTIPVTAFPENDLVIGEVAWLSSGHDSVAYRAFNRVQDREKIVSVKVESKESKVIRERDGTDGWIDNLLSMSYIGNVNGKEYYVDISDASGWAHIYLYPVDGGKEIALTKGEWEVVAILKVDTKKKLIYFTSTKYHSTTRHVYSVSYDTKVMTPLVNDKEAAYYTASFSAKGGYYILSYQGPNVPYQELYSTKDSKKPLKTITSNDALLEKLKEYKLPKVSFFEIKLPSGETLNVKQRLPPNFNPHKKYPVLFTPYGGPGAQEVSQAWNSLDFKSYITSDPELEYVTWTVDNRGTGYKGRKFRSAVAKRLGFLEAQDQVFAAKEVLKNRWADKDHIGIWGXSYGGFLTAKTLETDSGVFTFGISTAPVSDFRLYDSMYTERYMKTVELNADGYSETAVHKVDGFKNLKGHYLIQHGTGDDNVHFQNAAVLSNTLMNGGVTADKLTTQWFTDSDHGIRYDMDSTYQYKQLSKMVYDQKQRRPESPPMHQWSKRVLAALFGERAEE
What is the function of this protein?
Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.  Contributes to pathogenicity.
What are the official names of this protein?
Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DppIV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Secreted.
Protein: KCNH2_RABIT
Sequence: MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPARDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRPGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVPAMDNHVAGLGPAEERRALVGSCSPPPPVSAPGPHPSLRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGALPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPAPECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLLLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQMGKPYNSSGLGGPSIKDKYVTGLYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKDCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTEWEGGFNRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLTEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPAPSLLNIPLSSPSRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPFPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
What is the function of this protein?
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel.  Channel properties are modulated by cAMP and subunit assembly.  Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily H member 2, Ether-a-go-go-related gene potassium channel 1, ERG-1, Eag-related protein 1, Ether-a-go-go-related protein 1, RERG, ra-erg, Voltage-gated potassium channel subunit Kv11.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SKIP3_ARATH
Sequence: MIRLRTLIEKNRSESRKKIVSSTLDSLPEGCISNIISFTSPEDACVAAAVSKIFESAVKSDIVWEKFLPTDYESLITPSRVFSSKKELYFSLCNDPLLIEDGKMSLWLEKASGKRCIMLSATAMNLSSMADMSQRFLWIPCPESRFETVAALREAYRFEFNCRMNTRVLSLRTRYSVYIVFKKADNWCGFKGVSIEAVVGIVGEESFRSFICFDTHGKGQARKRKVVAKPELREDGWMETEIGEFYNEGGLMSSDEVEISTVEGKYAQQKRGLVILGIEIRPAKILEEFSVCRL
What are the official names of this protein?
F-box protein SKIP3, F-box protein PP2-B9, Protein PHLOEM PROTEIN 2-LIKE B9, SKP1-interacting partner 3.
Protein: GDH_RHIL3
Sequence: MSYQQKFRLDGERAVVTGGGRAIGLCCTEALAEAGAAVVVIERSEADAEQALALRNRGYDVEVRVGDVTDAARMDAIATELADGGRPATILVNNAGIGQSGIPAQDLTDADWLRMMDVNLNGVFWCSRAFGRSMISMKRGAIVNLGSMSGTICNRPQPQTAYNVSKAAVHHLTRSLAAEWAHHGIRVNAVAPTYIETPMVVAVEANRERIPLWLADTPMARMGTPEEVASAVLFLASGAASLMTGAIVNVDAGFTCW
What is the function of this protein?
Catalyzes the oxidation of galactitol to D-tagatose.  Also catalyzes the oxidation of a wide range of substrates, including polyvalent aliphatic alcohols and polyols, to the corresponding ketones and ketoses.  Galactitol is the preferred substrate.
What are the official names of this protein?
Galactitol 2-dehydrogenase, GDH, RlGDH.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MNMA2_GEOKA
Sequence: MNKAPHETRVVVGMSGGVDSSVAALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYEDVVRVCNQIGIPYYAVNFEKQYWDKVFTYFLNEYKAGRTPNPDVMCNKEIKFKAFLEHAMSIGADYIATGHYARVEFRDGEYKMLRGADPNKDQTYFLNQLGQAQLSKVMFPIGHLQKADVRRIAKEAGLATAGKKDSTGICFIGERDFKEFLSHYLPAQPGVMKTLDGEVKGRHDGVMYYTIGQRHGLGIGGSGEPWFVVGKDVRENVLYVAQGFENEYLYSTSLKAVDVNWVSDRKPEAPFRCTAKFRYRQPDVGVTVHPLADGGAEVVFDAPARAVTPGQAVVFYNGEECLGGGTIDEVFRNGEKLWYVG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 2.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUKF_CROS8
Sequence: MSTFSQTVPELVAWARKNDFSIQLPVDRLAFLLAIATLNGERLDGEMSEGELVDAFRHVSDAFEQSTETVAQRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVASELKRAADAAQEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRIMDEQQQLVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLQIQEATLGRDDLHFVDRLTYDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQNYFDAPWALTYASADRLLDMRDEEMTLRDEEVTGELPPDLEFEEFNEIREQLAAMIEAQLNVYRERQQPLDLSVVMRDYLTQFPRARHFDVARIVVDQAVRLGVAEADFTGLPAKWQPINDYGAKVQANVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: YEGR_ECOLI
Sequence: MKKIAAISLISIFIMSGCAVHNDETSIGKFGLAYKSNIQRKLDNQYYTEAEASLARGRISGAENIVKNDATHFCVTQGKKMQIVELKTEGVGLHGVARLTFKCGE
What are the official names of this protein?
Uncharacterized protein YegR.
Protein: RL18_SHEB8
Sequence: MDKKTSRLRRATRARKKIQELGVNRLVVHRTPRHIYAQVINPEAQVLAAASTVEKAVKELLKSTGNVDAAKAVGKFVAERAIEKGVTSVAFDRSGFKYHGRVAALADAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: Y317_METJA
Sequence: MKPKYALRKDMIGEFTLNKSFNTYRGKVLKADFNGPIEGIVMKNKKEHIYFYPLLALHMVKPLNCVPINVIPKTSLPTNPKNVHIKEALSRIVGRTLKVYYETPKTSYLGRLLGFTRGVFSWTLVLEIHGEVVLLFNPDYIVYYGTKWKFLKNNPPYKPPRLMNITKTANYLKRCLLEDVIIEPEYPRINIEDKVFVYPYGVVSKDDYLGKTVEDILKEKEFLI
What are the official names of this protein?
Uncharacterized protein MJ0317.