PharMolix/UniProtQA huggingface dataset:
Protein: RSMA_STRPQ
Sequence: MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEIDQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDILKADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRISAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMMRRDQPLIEVKDEDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKAKLEKGLALADIKSSIRGEALSIQDFGKLADALKEVGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG023_CWPXB
Sequence: MFDYLENEEVALDELKQMLRDRDPNDTRNQFKNNALHAYLFNEHCNNVEVVKLLLDSGTNPLHKNWRQLTPLGEYTNSRHGKVNKDIAMVLLEATGYSNINDFNIFTYMKSKNVDIDLIKVLVEHGFDFSVKCEKHHSVIENYVMTDDPVPEIIDLFIENGCSVIYEDEDDEYGYAYEEYHSQNDDYQPRNCGTVLHLYIISHLYSESDSRSCVNPEVVKCLINHGINPSSIDKNYCTALQYYIKSSHIDIDIVKLLMKGIDNTAYSYIDDLTCCTRGIMADYLNSDYRYNKDVDLDLVKLFLENGKPHGIMCSIVPLWRNDKETISLILKTMNSDVLQHILIEYITFSDIDISLVEYMLEYGAVVNKEAIHGYFKNINIDSYTMKYLLKKEGGDAVNHLDDGEIPIGHLCKSNYGRYNFYTDTYRQGFRDMSYACPILSTINICLPYLKDINMIDKRGETLLHKAVRYNKQSLVSLLLESGSDVNIRSNNGYTCIAIAINESRNIELLNMLLCHKPTLDCVIDSLREISNIVDNAYAIKQCIRYAMIIDDCISSKIPESISKHYNDYIDICNQELNEMKKIIVGGNTMFSLIFTDHGAKIIHRYANNPELRAYYESKQNKIYVEVYDIISNAIVKHNKIHKNIESVDDNTYISNLPYTIKYKIFEQQ
What is the function of this protein?
Substrate-specific adapter of SKP1-containing E3 ubiquitin-protein ligases which mediate the ubiquitination and subsequent proteasomal degradation of host target proteins.  Prevents activation and subsequent nuclear localization of NF-kappa-B in infected cells, by targeting NF-kappa-B RELA subunit to the SCF E3 ligase complex.
What are the official names of this protein?
Ankyrin repeat domain-containing protein OPG023, Host range protein 1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG023 family.
Protein: OHRA_BACSU
Sequence: MSQPLFTATVSAVGGREGKVISSDRVLELDVAMPGTPRAKKLEKATNPEQLFAAGYAACFDSALQLVARTERVKVETEVTANVSLLKDEADQGYKLGVTLQVKGEGVSASELEALVKKAHGVCPYSKATSGNIDVTLEVAE
What is the function of this protein?
Involved in organic hydroperoxide resistance.
What are the official names of this protein?
Organic hydroperoxide resistance protein OhrA.
What is the protein family that this protein belongs to?
Belongs to the OsmC/Ohr family.
Protein: SYGB_SHESA
Sequence: MNFENLLIELGTEELPPKALRKLAESFLANFTEELTKADLAFKSAVWYAAPRRLAINVTELALAQADKIVEKRGPAVSSAFDAEGKPTKAAEGWARGNGITVDQAERLVTDKGEWLVYNAKVEGVETKSLIAAMAQRALDKLPIPKPMRWGSSKTQFIRPVHTATMLLGSELIEGELLGIKSARNVRGHRFMGTGFELDHADNYLTLLKEKGKVIADYESRKALIKADAEKAAAKIGGTADIEDDLLEEVTSLVEWPVVLTASFEEKFLNVPSEALVYTMKGDQKYFPVFDDAGKLLPNFIFVANIESKDPAQIIAGNEKVVRPRLADAEFFFNTDKKHTLESRLPSLETVLFQQQLGTLKDKVTRISALAAFIAEQTGANAVDAARAGLLSKTDLMTNMVMEFTDTQGTMGMHYARLDGETEAVALAMEEQYKPKFSGDTVPTAAVSCAVALADKLDTLVGIFGIGQAPKGAADPFALRRAAIGVLRIIVENKLPLDLVTLIAKAQELHGTNLSNANASDEVLEFLMARFRAWYQDKGIEVDVILAVLARRPTRPADFDSRINAVSHFRSLEASSALAAANKRVSNILAKVEGELPTTINSALLAEAAEQALAAKLAELQPQLAPLFANADYQQALTLLASLRESVDQFFEDVMVMADDEALKNNRLALLNNLREQFLHVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3PC_MAGLI
Sequence: MGGKKIKIGINGFGRIGRLVARVALQRDDVELVAVNDPFITTDYMTYMFKYDSVHGQWKHHELKVKDSKTLLFGEKPVTVFGVRNPEEIPWGETGAEFVVESTGVFTDKDKAAAHLKGGAKKVIISAPSKDAPMFVVGVNEHEYKSNIDIVSNASCTTNCLAPLAKVINDKFGIVEGLMTTVHSITATQKTVDGPSSKDWRGGRAAGFNIIPSSTGAAKAVGKVLPALNGKLTGMAFRVPTVDVSVVDLTVRLEKAASYEEIKAVIKAESEGKLKGILGYTEEDVVSTDFIGDNRSSIFDAKAGIALNEHFVKLVSWYDNEWGYSSRVIDLILIVHMASCQ
What is the function of this protein?
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.  Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOX9_PANTR
Sequence: MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLGDQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQTHSPQHWEQPVYTQLTRP
What is the function of this protein?
Transcription factor that plays a key role in chondrocytes differentiation and skeletal development.  Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes COL2A1, COL4A2, COL9A1, COL11A2 and ACAN, SOX5 and SOX6.  Also binds to some promoter regions.  Plays a central role in successive steps of chondrocyte differentiation.  Absolutely required for precartilaginous condensation, the first step in chondrogenesis during which skeletal progenitors differentiate into prechondrocytes.  Together with SOX5 and SOX6, required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes, the second step in chondrogenesis.  Later, required to direct hypertrophic maturation and block osteoblast differentiation of growth plate chondrocytes: maintains chondrocyte columnar proliferation, delays prehypertrophy and then prevents osteoblastic differentiation of chondrocytes by lowering beta-catenin (CTNNB1) signaling and RUNX2 expression.  Also required for chondrocyte hypertrophy, both indirectly, by keeping the lineage fate of chondrocytes, and directly, by remaining present in upper hypertrophic cells and transactivating COL10A1 along with MEF2C.  Low lipid levels are the main nutritional determinant for chondrogenic commitment of skeletal progenitor cells: when lipids levels are low, FOXO (FOXO1 and FOXO3) transcription factors promote expression of SOX9, which induces chondrogenic commitment and suppresses fatty acid oxidation.  Mechanistically, helps, but is not required, to remove epigenetic signatures of transcriptional repression and deposit active promoter and enhancer marks at chondrocyte-specific genes.  Acts in cooperation with the Hedgehog pathway-dependent GLI (GLI1 and GLI3) transcription factors.  In addition to cartilage development, also acts as a regulator of proliferation and differentiation in epithelial stem/progenitor cells: involved in the lung epithelium during branching morphogenesis, by balancing proliferation and differentiation and regulating the extracellular matrix.  Controls epithelial branching during kidney development.
What are the official names of this protein?
Transcription factor SOX-9.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF5A4_SOLTU
Sequence: MSDEEHQFESKADAGASKTYPQQAGTIRKSGYIVIKGRPCKVVEVSTSKTGKHGHAKCHFVAIDIFTGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDGFVSLLTDNGNTKDDLRLPTDDSLLSQIKDGFAEGKDLVVSVMSAMGEEQINALKDIGPK
What is the function of this protein?
The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Eukaryotic translation initiation factor 5A-4, eIF-5A-4, eIF-4D.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
Protein: ENO_DORPE
Sequence: MVIKKVHSRQIFDSRGNPTVEVDLWTDKGMFRAAVPSGASTGIYEALEMRDKDAKNYHGKTLFNAVGNVNKIIAPALVDKKMDEKDQTAVDNFLLALDGTENKNKLGANAILGVSLAVCKAGAAAKGVPLYRHIADLAGNKEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGAKNFTEAMKMGTEVYHHLKSVIKKKYGQDACNVGDEGGFAPNILDNKEGLELLKTAIANAGYTAEIEIGMDVAASEFCKEKKYDLDFKNPDSNPNDWLTSDQLADVYKDFVKNYPVVSIEDPFDQDDWEAYTKMTKDMDIQIVGDDLLVTNPKRVQKGIDLKAANALLLKVNQIGSVTESIQACKMSQDAGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGDKAVFAGKKFRNPLK
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRFC_ECOLI
Sequence: MYTQTLYELSQEAERLLQLSRQQLQLLEKMPLSVPGDDAPQLALPWSQPNIAERHAMLNNELRKISRLEMVLAIVGTMKAGKSTTINAIVGTEVLPNRNRPMTALPTLIRHTPGQKEPVLHFSHVAPIDCLIQQLQQRLRDCDIKHLTDVLEIDKDMRALMQRIENGVAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDFPFSAYAAIEHIPVIEVEFVHLAGLESYPGQLTLLDTPGPNEAGQPHLQKMLNQQLARASAVLAVLDYTQLKSISDEEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTLMKGCITPQQIFPVSSMWGYLANRARYELANNGKLPPPEQQRWVEDFAHAALGRRWRHADLADLEHIRHAADQLWEDSLFAQPIQALLHAAYANASLYALRSAAHKLLNYAQQAREYLDFRAHGLNVACEQLRQNIHQIEESLQLLQLNQAQVSGEIKHEIELALTSANHFLRQQQDALKVQLAALFQDDSEPLSEIRTRCETLLQTAQNTISRDFTLRFAELESTLCRVLTDVIRPIEQQVKMELSESGFRPGFHFPVFHGVVPHFNTRQLFSEVISRQEATDEQSTRLGVVRETFSRWLNQPDWGRGNEKSPTETVDYSVLQRALSAEVDLYCQQMAKVLAEQVDESVTAGMNTFFAEFASCLTELQTRLRESLALRQQNESVVRLMQQQLQQTVMTHGWIYTDAQLLRDDIQTLFTAERY
What is the function of this protein?
Important for the colocalization of sister nascent DNA strands after replication fork passage during DNA replication, and for positioning and subsequent partitioning of sister chromosomes.  Does not have GTPase activity on its own.
What are the official names of this protein?
Clamp-binding protein CrfC, Clamp-binding sister replication fork colocalization protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half the protein co-localizes with beta sliding clamp (DnaN) at midcell, the rest without clamp in quarter-cell positions when chromosomes are condensed during DNA replication.
Protein: ACR10_ARATH
Sequence: MGILSDDVVIISQSEKEGDPSVITINCPDKTGLGCDLCRILLFFGLNIVRGDVSTDGKWCYLVFWVIGKPNTRWNLLKMRLVEASPSFSWAFGISRCYLSDSESQPPKLPDLFLLKLACSDRTGLLYDVTEVLYKLEINIEKVKISTTPDGKVMDLFFVTDTRELLGTVKRRNEVYEYLRDAIGDSMISYDIELVGPEITACSTSSSVAETLFSSDVSGEHSSGLHTSSNVSIAVDNSLSSAHTLIHITCQDHKGLLYDIMRTFKDFNIQISYGRFTIKLGKNCEIDLFIVQSDGRKILDSSKLNALITRLRAELQQPLRVVMMNRGPDTELLVTNPVELSGKGRPQVFHDIALALKKIDTCIFSAEIGRHVTGDREWEVYKVLINEEDSLPIPRSKIEEEVWKTLMGWE
What is the function of this protein?
May bind amino acids.
What are the official names of this protein?
ACT domain-containing protein ACR10, Protein ACT DOMAIN REPEATS 10.
Protein: PROA_SHIBS
Sequence: MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTCDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECF_RICTY
Sequence: MQIYPLRFVPNKINFDFMNFKKVSYSFSIILSLISLIWIGIYKFNFGIDFVGGIVIEVRLDRAPDLPKMRAVLSALGIGEVVLQNFESEHDLSIRFGSSSEENLMKNIDIIKTSLRNNFPYNFEYRKVDFVGPQVGRHLIEAGAMAMLFSFLAIMVYIGVRFEWYFGFGILIALVHDVILALGFMSITKLDFNLSTIAAVLTIIGYSVNDSVVIYDRIRENLRKYHKKNITEIINLSINETLSRTILTVITTLLANLALILFGGKAIHSFSVLVFFGIIAGTYSSIFISAPILTIFANRKFNKKVIER
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MBTB_MYCBO
Sequence: MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAALYDGREPPALGYTYQEYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR
What is the function of this protein?
Involved in the initial steps of the mycobactin biosynthetic pathway.  Putatively couples activated salicylic acid with serine or threonine and cyclizes this precursor to the hydroxyphenyloxazoline ring system present in this class of siderophores (By similarity).
What are the official names of this protein?
Phenyloxazoline synthase MbtB, Mycobactin synthetase protein B.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.
Protein: YHHH_ECOLI
Sequence: MSAEFMVICKKILFRNCVIVSLFVFTYNTWAQCNNNIKIMRKYESEGKYTVRNLVKNKAIALELAEIYVKNRYGQDAAEEEKPYEITELTTSWVVEGTIHSDQIAGGVFIIEIGKNDGRILNFGHGK
What are the official names of this protein?
Uncharacterized protein YhhH, ORF-B2.
Protein: PREP_PONAB
Sequence: MWRCGGRQGLGVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLIHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCRDPFFRMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPRDPQTALVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCILELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTAVPAQTPWDKPREFQITCGPDSFATDPSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLVDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRTQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMHLWSEIFNNPCFEEEEHFKVLVKMTAQELTNAIPDSGHLYASIRAGRTLTPAGDLQETFSGMDRVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMSQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQIIRKLVTEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYMDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFSLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPIAPSNKGMDYFLYGLSDGMKQAHREQLFAVSHDKLLAVSNRYLGTGKSTHSLAILGPENPKIAKDPSWTIR
What is the function of this protein?
Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing.  Has an ATP-independent activity.  Specifically cleaves peptides in the range of 5 to 65 residues.  Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.  Degrades the transit peptides of mitochondrial proteins after their cleavage.  Also degrades other unstructured peptides.  It is also able to degrade amyloid-beta protein 40, one of the peptides produced by APP processing, when it accumulates in mitochondrion.  It is a highly efficient protease, at least toward amyloid-beta protein 40.  Cleaves that peptide at a specific position and is probably not processive, releasing digested peptides intermediates that can be further cleaved subsequently.  It is also able to degrade amyloid-beta protein 42.
What are the official names of this protein?
Presequence protease, mitochondrial, Pitrilysin metalloproteinase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. PreP subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ATPH_PLETE
Sequence: MNPLVAATSVIAAGLAVGLAAIGPGIGQGTAAGYAVEGIARQPEAEGKIRGALLLSFAFMESLTIYGLVVALALLFANPFVS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LIP5_CANAL
Sequence: MLYLILFLIAPIYAGLIFPTKPSSDPFYNPPKGFENAAVGDILQSRATPKSITGGFTPLKIQNSWQLLVRSEDSFGNPNVIVTTVIEPVNADPSKIASYQVFEDAAKADCAPSYALQFGSDLTTFVTQAEMYLMAPLLDQGYYVVSPDYEGPKSTFTIGKQSGQAVLNSIRAALKSGKITNIKDDAKVVMWGYSGGSLASGWAAALQPSYAPELGGNLLGAALGGFVTNITATAQATDGTVFAGIVANALGGVANEYPEFKSILQSDTDKKSVFDEFDGHCLIDGVLNYIGTSFLTGDHKIFKTGWDILKNPKIGKVVEDNGLVYQKQLVPKIPVFIYHGSIDQIVPIVDTKKTYQNWCDAGISSLEFAEDASNGHLTEAIMGAPAALTWIIDRFDGKQTVSGCQHIQRFSNLEYPNIPSSIANYFKAAMDVVLHLGLGPDVQKDQVSPEGIKKLGSIEMRWL
What are the official names of this protein?
Lipase 5.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
Protein: PYP_CERS4
Sequence: MEIIPFGSADLDNILAREPQRAEYLPFGAVLLDRTGTILKYNRAEGGIANRNPADVIGKNFFNEIAPCAKGKRFHGEFLRFHQTGQVNVMFDYKFAYKGANVGVKIHMKSQPDGQSCWLFVKRV
What is the function of this protein?
This photoactive protein is a photoreceptor with kinetics similar to that of rhodopsin.
What are the official names of this protein?
Photoactive yellow protein, PYP.
What is the protein family that this protein belongs to?
Belongs to the photoactive yellow protein family.
Protein: POL2_CRLVP
Sequence: MEPERSQLAPEEVPDSFRVETPAAMLARLRAESAAKKEAARRAAMPYNDDLLVGSELTYLAKDDVFGCGRSALKRLFSRPSAEENVVVSHPLSVKEQVVRYQRPRTDHDPYVAVYTPLPHITEEQARKLMEKGFSNSSNVALDMAVQSHVGQGTPLLAMCGIMDSRTDDPNEALQVAGYFDLGRDRCDLISLPLINFPLNKEDFDDYMRGLYLCTMFHNVRGFQNNKALCSYSAVGFDQHKETPRCIRSRVKESWEDILARNNENEFSRVQSGQNLLNAIEKERNEAIPDVGAHQFACVPPSKGTPQTSLLTSDGVIKRPNFTLPRSASTRFNMPLNMRYSGRNSVDTARHSLTTNSGGRSTSLRQDPNLLEGQGPSIDFTKIIFPTVVERNFSNPRAEIVNTIKQLYGDTVETLSVNPPESYSAERLIGRVFSTLHGSFGATDLVEGKVLMSVKIVDLLSSANLGALLLAEVLGGNLTMRVTALITLNKYTSFALKLVYDELAQLAPDATNFGVASVLPGAIFPSQEKSFSFDFNIFSMGSYINFKENEGFGRISLVALSSPNLPDQMPDSANITLEFSVVNVDTSVYNLGQGQCLDLDRFPVHVTSKSKALSGGAKHAQAEFSLNLYELGPHFNRFQAICGHLAGYSGDLIIDWMISASALTNGRCYIVPVYDQNTFSEVSEEKLRQCKYVSKELSLNRSGTVHMPFSSSFGSYTKNKYPKLLFVFPGGISGPSGETIHVNIQVRDVLHFSGLGHQLLKPILAAEGPDPFSFHLFYLHCGTLKTESLNKGGMWCVPVSPINLAAMKHGTGSSLVFNESFVSKTHNWLHYMASCTAYWRGTLTYELRVTYNSRVNAVANLVAFYTSQVEDLFGFSDKAVGDTGIASICGDAFSVRISIPFVTPTLWLRTYRNAYDVFTSCNGSLYFHLPTSGVKSVQLFVRAESDFSFERFRALKAEYT
What is the function of this protein?
Capsid proteins VP20, VP24, and VP25 form a capsid enclosing the viral positive strand RNA genome.  Together they form an icosahedral capsid pseudo T=3 with a diameter of approximately 30 nm (Potential).
What are the official names of this protein?
RNA2 polyprotein, P2.
What are the subcellular locations of this protein?
[Movement protein]: Host cell junction, host plasmodesma. SUBCELLULAR LOCATION: [Capsid protein VP25]: Virion. SUBCELLULAR LOCATION: [Capsid protein VP20]: Virion. SUBCELLULAR LOCATION: [Capsid protein VP24]: Virion.
Protein: ARGC_BORA1
Sequence: MAQARNSRIKVGIVGGTGYTGVELLRLLSQHPDVELTAITSRKEDGLPVAEMYPNLRGHVKLAFSAPEKASLTDCDVVFFATPHGVAMAQAQALTAAGTRVIDLAADFRLQDTASFERWYKMPHGCPDILAKQSAYGLVELNRAAIAQAQVIGNPGCYPTTVILGLAPLLERKLIDTQALIADCKSGVSGAGRKAEVASLFSEASDNFKAYGVAGHRHHPEITEQLEKLAGGKVGLTFVPHLVPMIRGMFSTIYARILPEARETDFQALFEERYAGEAFIDVMPAGSLPETRSVRASNNLRIAVQRPGNGDQLIVLVVQDNLVKGAAGQAVQNMNLMFGLPETTGLNQVAILP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_THERP
Sequence: MRTVRDLEVEERRVLVRVDYNVPLEGGRVVDDTRIRATLPTLQWLLERRARIILCSHLGRPKGQVREELRLAPVAATLSGLLGQPVRSVRDIVGPEAQEMARRLQPGEVGMLENLRFDPREEQNDAEFAAALAALADCYVNDAFGAAHRAHASVVAVARLLPSAAGFLMEREVQALERVLRSDERPFVLVLGGAKVSDKIGVIENLLPRADALLLGGGMANTFLRARGLETGRSLVEEEKVPEAQRILDLAAARGVRVELPRDVVVAPTMSAVSQRRIVPVTAIPPDQAVYDIGPETVRAYSAVIAGARLLVWNGPMGVYEVPEFREGTKGIAEAVAGCSGFTLVGGGDSAAALQELGLAERVGHLSTGGGATLEYLEGRELPGVAVLMEEA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_STRPN
Sequence: MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHGLKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKETSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVRNTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVGRYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKIVYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYFLNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIVWLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQYDGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIADGPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDTKLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQEVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.