PharMolix/UniProtQA huggingface dataset:
Protein: IWS1_DEBHA
Sequence: MSDKEGETALYNDREEEARQFFSDSAEPQSQGGSNELAVNENEDNNNDEVEDDADENIYSIQAHKITGDEENNREVTMKKNVRKAKKYDEFKNERDEQGFVPMGENPEYGGMDYSNEDPQARKRRLLEEKMESAIKSKTSRRRRADEDDLERMQDDRIDFLKDQMIKAANLDVEKNSQGQIATEKLKLLNEVVDILSKADLAISILDNNLLEAVRLWLEPLPDASMPAYQIQKELIHSLTVLPIKTDHLIASGIGKVLVYYQRSKRTEANLKKVVDRLIGDWTRPILNKSDSYKDRTIQFNEYNKNRFTNQLSSARRSKPKEAKSLYEESAERRKRAAIPAARTTAYKIAPKVDPSLLRRQQLNSNGNNDERFKRINQKLTSMNFKKKSSKKSGPSIEGRNLTI
What is the function of this protein?
Transcription factor involved in RNA polymerase II transcription regulation.  May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
What are the official names of this protein?
Transcription factor IWS1.
What is the protein family that this protein belongs to?
Belongs to the IWS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TVA7_HUMAN
Sequence: MEKMRRPVLIIFCLCLGWANGENQVEHSPHFLGPQQGDVASMSCTYSVSRFNNLQWYRQNTGMGPKHLLSMYSAGYEKQKGRLNATLLKNGSSLYITAVQPEDSATYFCAVD
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 7.
What are the subcellular locations of this protein?
Cell membrane.
Protein: TUP1_DICDI
Sequence: MYGRTARASELLDNLKGEIDALNHELSLYKHQKDDYERKFQNQLAELNTIQQTLYDLERGQNKMKIHYEEEIRQLKRQLEQQNINASQRDLNSPSTFRSNSPAPPAQHNNNNNNIINNNNNNNNNNNNMQRNTPTPTIPDKGQPKQRQRSGSGEFYQQPGLGPQQLNFQQLNLQQQQQQLQQQQQQGSGQSFPSLSPLDSNRHPKEMGNNMSGNSMSMNNNNNNLNKKPDMEEVKEEDRRRHDTEMSEENGKEKGTDWLVGYNPSVQTNLNIDLLHNLQHNSVVCCVNFSNDGKYLATGCNRSAQIYDVDTGKKVHAFVDESEKDGDLYIRSVCFSPDGNYLATGAEDKTVKVWDIHTKKIQHTFYGHELDIYSLDYSSDGRFIVSGSGDKKAKIWDIEKGKCAFTLGNEEVGPKNGVTSVAMSPDGRLVAAGSLDNIVRLWDAQTGYFLERYEGHLDSVYSVAFSPDGKSLASGSLDKSLKLWDLSGSRSRSRCRATFNGHKDFVLSVAFSPDGSWLISGSKDRSVQFWDPRNGTTHMMLQGHKNSVISVALSPKNNSHGVFATGSGDFRSRLWKYDS
What is the function of this protein?
Acts as component of the trfA-tupA corepressor complex which is involved in the repression of many genes in a wide variety of physiological processes.  May also be involved in the derepression of at least some target genes.  The complex is recruited to target genes by interaction with DNA-bound transcriptional repressors.  The complex recruits histone deacetylases to produce a repressive chromatin structure, interacts with hypoacetylated N-terminal tails of histones H3 and H4 that have been programmed for repression by the action of histone deacetylases and interferes directly with the transcriptional machinery by associating with the RNA polymerase II mediator complex (By similarity).
What are the official names of this protein?
General transcriptional corepressor tupA.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TUP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MB43_EHV1V
Sequence: MMYQPDREPGEDSCLVLSSSSVQRCTGSQRGCMPCTWAASKAFVGIGLQACVLTSSILHIDLLTRNSTCLILMIISMYVLSLIRVPISKMETIVTVCRSIQALATLVAASVWVAGSAVKKEHLLIVVTVCILFVFIAGTQISLFYVICSANGTGTHFRASLLAIIGGCVLGVSVKLVELKDVPIGIGIAIAIIASCQDFGLALRDTCHYRIGRYACMRTFTDLGRGINYRWVTDVEAVPKIEEVAEEKVSLFKFFKEMPGVIFSPAVGTHATPIIWIVLRLVYGISNVWQTPAYVVFCLTVGHVSAMLLEQLVIRVNYTAEASSGIHSTAHAVCMVLAAFGYGVAAPLSLAFTVSGGILGALYLRKRATGARRLAATHISRWLIVCVYVAAGLCYATIITH
What are the official names of this protein?
Membrane protein UL43 homolog, Membrane protein ORF17.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL43 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PEPQ_SALAR
Sequence: MESLAALYKNHIVTLQERTRDVLARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEEIEVVALPKADGIGSQLPVARGNIGYIGSAPERALQLDIAANNINPKGVIDYLHYYRAYKTDYELACMREAQKMAVSGHHAAEEAFRSGMSEFDINLAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPSEMRSFLLDAGAEYNGYAADLTRTWSAKNDNDYAQLVKDVNDEQLALIATMKAGISYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPSKYPYLRCTRVLQPRMVLTIEPGIYFIESLLAPWREGPFSKHFNWQKIEALKPFGGIRIEDNVVIHENGVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: TORA_VIBCH
Sequence: MAITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQELKALELDTHPTEMLNGIQGILYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDEAIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAMMQRAVGMHGNYITKVGDYSTGAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLDQLKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKFIETYCLGFEEFIPYVLGKSKDKVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWCIQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGIGVPSTGFAGPGGFPRNLDQGAKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQDRNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHRLVDPLFQSRTDFEIMTELTRRFGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEEFWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEITSRKIGRYGYEHCQEHPMWFEKTERSHGGPGSDKHPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPLDAKAKGIKDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTLDLGTSELAQATSANTCIVDFEKFRGEVPPVTSFGGPIEVI
What is the function of this protein?
Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.
What are the official names of this protein?
Trimethylamine-N-oxide reductase, TMAO reductase, Trimethylamine oxidase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RGGA_TOBAC
Sequence: RGGGRGGPRGGGRGRGPGRGRGFNQESADDENAFGSNNGFSGRYRVQEDGESGKLSERRGGYGGPRGGFHGGRRGGFNNGDAAEGEGERPRRVFDRRSGTGRGNEYIKREGSGRGNWGTPADDIAQETEVPVNDGEKIVEAEKEAGQEEAEDTNKDSTAAEPEEKEPEEKEMTLEEYEKLMEEKRKALLALKPEERKVNLDKELESMQLLSNKKNDDEIFIKLGSEKEKRKEAVEKARKTQSINEFLKPAEGENYSRRGGRGRGPGRGRGGFGGGVGGNKSFSAPSIEDVGQFPSLVAK
What is the function of this protein?
Binds RNA.
What are the official names of this protein?
RGG repeats nuclear RNA binding protein A.
What is the protein family that this protein belongs to?
Belongs to the RGGA protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region.
Protein: CPSF4_DROME
Sequence: MDILLANVSGLQFKAERDLIEQVGAIPLPFYGMDKSIAAVCNFITRNGQECDKGSACPFRHIRGDRTIVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSRFNACHNKECPFLHIDPQSKVKDCPWYKRGFCRHGPHCRHQHLRRVLCMDYLAGFCPEGPSCKHMHPHFELPPLAELGKDQLHKKLPTCHYCGELGHKANSCKQYVGSLEHRNNINAMDHSGGHSGGYSGHSGHIEGADDMQSNHHSQPHGPGFVKVPTPLEEITCYKCGNKGHYANKCPKGHLAFLSNQHSHK
What is the function of this protein?
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.  Has endonuclease activity.  Binds RNA polymers with a preference for G- and/or C-rich clusters.  Binds single-stranded DNA non-specifically.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 4, Cleavage and polyadenylation specificity factor 30 kDa subunit, Protein clipper.
What are the subcellular locations of this protein?
Nucleus.
Protein: CP51_TRYCC
Sequence: MFIEAIVLALTALILYSVYSVKSFNTTRPTDPPVYPVTVPFLGHIVQFGKNPLEFMQRCKRDLKSGVFTISIGGQRVTIVGDPHEHSRFFSPRNEILSPREVYTIMTPVFGEGVAYAAPYPRMREQLNFLAEELTIAKFQNFVPAIQHEVRKFMAENWKEDEGVINLLEDCGAMIINTACQCLFGEDLRKRLNARHFAQLLSKMESSLIPAAVFMPWLLRLPLPQSARCREARAELQKILGEIIVAREKEEASKDNNTSDLLGGLLKAVYRDGTRMSLHEVCGMIVAAMFAGQHTSTITTSWSMLHLMHPKNKKWLDKLHKEIDEFPAQLNYDNVMDEMPFAERCVRESIRRDPPLLMVMRMVKAEVKVGSYVVPKGDIIACSPLLSHHDEEAFPNPRLWDPERDEKVDGAFIGFGAGVHKCIGQKFALLQVKTILATAFREYDFQLLRDEVPDPDYHTMVVGPTLNQCLVKYTRKKKLPS
What is the function of this protein?
Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis.  It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity).  Favors C4 dimethylated substrates, the substrate preference order is 24-methylenedihydrolanosterol > 24,25-dihydrolanosterol > lanosterol > obtusifoliol > norlanosterol.
What are the official names of this protein?
Sterol 14-alpha demethylase, Tc14DM, Cytochrome P450 51, Lanosterol 14-alpha demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ALF_STRP8
Sequence: MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAPVLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTSIMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAKAMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQIKEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAVQGAVEERIDVFGSANKA
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: KDM6B_HUMAN
Sequence: MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAADVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDPKNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLEQYRTEELAQAYDAFTLAPASTSR
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914).  Demethylates trimethylated and dimethylated H3 'Lys-27' (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914).  Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529).  Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402).  Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 6B, JmjC domain-containing protein 3, Jumonji domain-containing protein 3, Lysine demethylase 6B, [histone H3]-trimethyl-L-lysine(27) demethylase 6B.
What is the protein family that this protein belongs to?
Belongs to the UTX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSRQ_BRUA2
Sequence: MAAATGTRKKKTPRPGQWKLWLLYTAGFVPAVWTFYLGATGQLGADPVKTFEHLLGLWALRFLILTLLVTPIRDLTGITLLRYRRALGLLAFYYALMHFTTYMVLDQGLNLSAIITDIVRRPFITIGMISLALLVPLALTSNNWSIRKLGRRWSSLHKLVYIAIAGSAVHFLMSVKSWPAEPVIYAAIVAALLLWRLARPYLRTRKPALRPRGEAIALRK
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOSB_BACLD
Sequence: MENNKILGINHLLFSVSDLSVSISFYEKVFDAKWLVKAEKTAYFDLNGIWLAFNEEKDIKRQEIHDSYTHIAFSIQQEDLPFWEKKLHDLGVNVLKGRKRHEGDRDSIYFSDPDGHKFELHTGSVFDRLQYYQNEKPHLSFHEGHIKALYDRNK
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAGU_BACAN
Sequence: MKKKILFWVLGILGVLIIGGGIYAYNVYSSVSNTLKEVHQPLKRDQNNSNVGEKVSKSEPVSILLLGADERGEDKGRSDSLMVITLNPKNNSMKTVSIPRDTYTEIVGKGKSDKINHAYAFGGVDMSVATVENFLNVPINYYIEVNMEGFKDIVDAVGGVDVKNDLEFTQDGHHFAKGNIHLTGDQALAFTRMRKQDPRGDFGRQMRQRQVMQGVIKKGASFSSLTGYGDVLSAIQKNVKTNLTQDQMFDMQKNYKDCLKNSEDIQIPGDGHKAADGIWYYYVPDAAKQDLTNKLRTHLEVTK
What is the function of this protein?
May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).
What are the official names of this protein?
Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU.
What is the protein family that this protein belongs to?
Belongs to the LytR/CpsA/Psr (LCP) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: NUOF_MYCTO
Sequence: MTTQATPLTPVISRHWDDPESWTLATYQRHDRYRGYQALQKALTMPPDDVISIVKDSGLRGRGGAGFATGTKWSFIPQGDTGAAAKPHYLVVNADESEPGTCKDIPLMLATPHVLIEGVIIAAYAIRAHHAFVYVRGEVVPVLRRLHNAVAEAYAAGFLGRNIGGSGFDLELVVHAGAGAYICGEETALLDSLEGRRGQPRLRPPFPAVAGLYGCPTVINNVETIASVPSIILGGIDWFRSMGSEKSPGFTLYSLSGHVTRPGQYEAPLGITLRELLDYAGGVRAGHRLKFWTPGGSSTPLLTDEHLDVPLDYEGVGAAGSMLGTKALEIFDETTCVVRAVRRWTEFYKHESCGKCTPCREGTFWLDKIYERLETGRGSHEDIDKLLDISDSILGKSFCALGDGAASPVMSSIKHFRDEYLAHVEGGGCPFDPRDSMLVANGVDA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit F, NADH dehydrogenase I subunit F, NDH-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
Protein: RS2_PARP8
Sequence: MAVTMRQMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMYNDALKYVRQLAANRGTILFVGTKRQSRDTIAEAAQRAGMPYVNARWLGGMLTNFKTLKVSIKRLKDMEAAVEAGELEKMSKKEALLFEREIAKLQKSIGGVKDMGGIPDAIFVVDVGYHKIAVTEANKLGVPVIAVVDTNHSPEGVDYVIPGNDDASKAVALYTQGVADAILEGRANAVNEVVQAVRGGDGDEFVEVNGEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL30_WIGBR
Sequence: MNKLKITQIKSSIGCLKKHKSTLYGLGLRHIGHTVIRQNSPRLLGMINSISYLVKIKD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: Y3643_ORYSJ
Sequence: MTNAKMTFAVQFSERYINKYIGSPIDDLMVSMAGTTQSYQMRLKRSKDSRAMLTTGWNQLIDAKAFDEGDVCLFHFKEVDDVLVLKVHVLK
What are the official names of this protein?
B3 domain-containing protein Os03g0164300.
What are the subcellular locations of this protein?
Nucleus.
Protein: FETP_BUCBP
Sequence: MNKKNDINRKIFCNFFKKYEEGLTYIPYPGLLGHKIYNEISKLAWNKWILQQTIIINEKKMNMLNKNDQKKIENYMIKFLFKNKQQL
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: SYT_BORBZ
Sequence: MSKDLDKEDILYKKRHSIAHVMAEAVLDLFPNTKIAIGPPIKDGFYYDFEFKKQITEDSLLDIENRMREILKTGSSFEKEIISVEQALEIFKDEPYKIDLIKNFDLQNEVSIYKSHNFVDLCRGPHVENMNKIDPKAFKLTSIAGAYWRGSEKNPMLTRIYGTLWNNEKELRSYLNLREEIKKRDHRKLGKELDLFSIHEEIGPGLVFFHPNGAKIRALIEDFWREEHSKNGYDILFTPHIGKSWLWQTSGHLDFYKDSMFEKIEMDKSDYYLKPMNCPFHIAIYNTGKHSYRDLPFRWAELGTVYRYEKIGALHGMMRARGFTQDDAHIICTHSQVLDEIKEVLRFAIYMWSKFGFSNPKAYLSTKPDKSVGNDSDWEMSLKVLEETLSDFEVPYEIDKGGGAFYGPKIDLKIVDSLEREWQMSTIQFDFNLPERFNMTYTAEDGKEKRPFMIHRALLGSIERFFGILVEHYGGAFPLWLSPVQVVIIPVNNIVEDYAIKVFNKFKNEGIRIKLDNSSSRMNAKIREYQAKKIPYMFIIGEREATEERISIRTRTNEQINGMKLDEALKFILFKIRDKEI
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_COLP3
Sequence: MAKEKFERNKPHVNVGTIGHVDHGKTTLTAAISAVLTKVHGGEVKDFAQIDNAPEERERGITINTSHIEYDTEARHYAHVDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHILLSRQVGVPFIIVFMNKCDVVDDEELLELVEMEVRELLSEYDFPGDDLPVIQGSALGALQGDEAWEAKIIELADALDTYIPEPERAIDGAFIMPIEDVFSISGRGTVVTGRVERGIIKIGEEVEVVGIRDTQKSTCTGVEMFRKLLDEGRAGENCGVLLRGLKREDVERGQVLCAPGSILPHTKFESEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDITGAVELPEGVEMVMPGDNLKFVVELINPVAMDEGLRFAIREGGRTVGAGVVSKIMA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_PROA2
Sequence: MRIIFMGTPDFAVPSLKAIAAMDGDFEVQLVVTGKDKPRRSKRSEPEPTPVKKAARELGIPVMEVDDVKDERFVDTVARYRPDVLVVAAFRILPPAVYEQARLGAFNLHASILPRYRGAAPVNWAIINGERESGVTTFFLRKSVDTGNMILQEKTPVYPEENAGELAARLAEIGAGAVVKTLELIRDGRVEPLLQNDTLATRAPKLSTENTRIDWVQPVDALCDFIRGLAPRPAAWAIFNHKKVKIFKASVADFHQPEAEEQSAIPGRIAVENNRLFVMGLDGWIEILSLQMEGKKVMQSHEFCCGFRCDEECPVFS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RL16_CORA7
Sequence: MLIPKRVKYRRQHRPTRSGVSKGGNRINFGDYAIQALEPAYITNRQIEAARIAINRHVKRGGKVWINIFPDRPLTQKPLGVRMGSGKGPVEKWVANVKPGRILFEMTYPNEATAIEALRRAGQKLPCKVRIIKKEDQF
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: A18_MYXVL
Sequence: MSVCSEIDYALYTELKKFLNSQPLFLFNADKNFVEVVPSSSFKFYIPIGVFSNSDVALIRPVHTTCTNHIESADATFPNLYPLQKRVVAEVTTSMRQKLSTHRPMYMTLHLSCGFGKTITACYLMVVHRRKTVICVPNKMLIHQWKAAVELTKLSYIISTDGVSVLLKQLRTKTADVLIIVSRHLSNDYFCKKIHDEYDTFILDESHMYNLMNNSALTKFLTFYPPRICYFLTATPRLANRIYCNDVVNVLKVSTLMKRLKIVEYFFEPYSTECIRQMAKHLNTENNKYHIYTEKILAEDLPRNNLIVDTVSREFKHGLVERVIVVVKLRKHMTFFYDKFVEEFGTDYVYLGDAKNKDTSAVVKSLLQKKKFIFVSTSHYSGTGLDIPSLDSLVICCAVLNSMQIEQLLGRVCRESESVKKTVFLFPNTSIREIKHSLGFFTERIVSVSTDKLGFQQEGKEGTKEEPALTKAFSSQIR
What is the function of this protein?
DNA helicase which seems to act as a postreplicative transcription termination factor.  Involved in ATP-dependent release of nascent RNA.  Forms a stable complex with single-stranded DNA, and to a lesser extent RNA (By similarity).
What are the official names of this protein?
Transcript termination protein A18.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Poxviruses subfamily.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: NRH2_ORYSJ
Sequence: MEARLSTGEKTKKMATTSRPSSPLPPEEETAAETTTSEEEEQQQMERFYALVANVRALRAMFKEAALPSCREDDVSGGGGGEQRQKRPRAAPWRPAFEMAVFECGGGGGTTTDDIEAATTKGQDGNCKKGKRSEANAAAEEDKGEVIEGKPVAIAIVADGPGKSTTMPDSN
What is the function of this protein?
Binds to and weakly represses NPR1/NH1-mediated transcriptional activation of LG2 in vitro.
What are the official names of this protein?
NRR repressor homolog 2.
What is the protein family that this protein belongs to?
Belongs to the NPR1-interactor family.
What are the subcellular locations of this protein?
Nucleus.