PharMolix/UniProtQA huggingface dataset:
Protein: TOLB_PECAS
Sequence: MKQVLKVAVSFLMLWAAVLHAEVRIEITQGVDSARPIGVVPFKWAGPGAAPEDVGAIVGADLRNSGKFNPIDANRMPQQPATASEVTPAAWTALGIDAVVVGQVQPSADGSYLVSYQLVDTSGNPGNVLAQNQFKVTKQWLRYAAHTASDEVFEKLSGIKGAFRTRIAYVVQTNGGQFPYELRVADYDGYNQFVVHRSPQPLMSPAWSADGSKLAYVTFESGRSALVIQTLANGAIRQVASFPRHNGAPSFSPDGSKLAFALSKSGSLNLYVMNLGSGQISPVTDGRSNNTEPTWFPDSQTLAYTSDQAGRPQVYKVNANGGAPQRVTWEGSQNQDSDVSADGKFLVTVSSNGGAQHISKLDLVTGAVQVLTDTFLDETPSIAPNGTMVIYSSKQGLGSVLQLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: UGPC_ECO57
Sequence: MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKSTLLRMVAGLERVTEGDICINDQRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLKIRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVRDPAVFLFDEPLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGTPVEVYEKPASLFVASFIGSPAMNLLTGRVNNEGTHFELDGGIALPLNGGYRQYAGRKMTLGIRPEHIALSSQAEGGVPLVMDTLEILGADNLAHGRWGEQKLVVRLAHQERPTAGSTLWLHLPENQLHLFDGETGQRV
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CMOB_YERPS
Sequence: MIEFGDFYRLIAKGPLSPWLDILPAQLSAWQRESLHGKFKTWFNAVEHLPQLTPTTLDLHSGVRAEMSPPISAGQREGMENMLRALMPWRKGPFSLYGLEIDTEWRSDWKWQRVLPHISPLAGRTILDVGCGSGYHLWRMIGEGAHLAVGIDPMQLFLCQFEAIRKLLGGDQRAHVLPLGIEQLPELAAFDTVFSMGVLYHRRSPLDHLYQLKNQLVTDGELVLETLVVEGDSQQVLVPGDRYAQMRNVYFIPSAPALKAWLEKCGFVDVRIADMAVTTTEEQRRTDWMTSESLAEFLDPHDHSKTVEGYPAPLRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: COX2_FELCA
Sequence: MAYPFQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTQELKPGELRLLEVDNRVVLPMEMTIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMATRPGLYYGQCSEICGSNHSFMPIVLELVPLTYFEKWSASML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SUB3_PSED2
Sequence: MLFSKSLVALVACFLPLIVSATELKLRNAAATNVAADSYIVVYKDIDDSTFESEMFNVHSFLSKRDSTFRGLGHKYKMPKFKGYQIESDMDTVNRISQSPHVAYVDKDVKVSAYDLSVRIGAPWGLDRISHRNGTSPGLEEYTYDSSAGGGTTIYIIDTGVYIEHVEFEGRATFGANFIPGSPDTDEDGHGTHVAGIAAGANFGVASKAKIIAVRVLDANGDGKGSNVLAGMQWAADDAGKKNQTAKSVINMSLGADYSEAFNKATEAIIAKGIVVVAAAGNEDANASGVSPASTVDAITVGATDRNDSRAAFSNWGVALDVFAPGVDILSAWIGGKDANKTISGTSMACPHVAGLAAYFIGLEKNGTSTPSKIATKIKGVATKNVVLHPKNSRDNLAYNDDGY
What is the function of this protein?
Secreted subtilisin-like serine endopeptidase (PubMed:25944934).  Mediates the degradation of collagen, the major structural protein in the mammalian host.  Degrades the nonhelical regions of collagen that function in the cross-linking of the helical components (By similarity).  May function as virulence factor involved in epidermal wing necrosis observed in white nose syndrome (WNS) in bats (By similarity).
What are the official names of this protein?
Subtilisin-like protease 3, Destructin-3, Serine protease 3, PdSP3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: QSPP_NEMVE
Sequence: MSNQVMLPRESGSFIASHSKDVSLCEEGISRASEIVFKSLKSNAYSYKTWKDHELHPKEMSKATVDWIFVLDTLNFSFWVDDGLEPWTIRHKGKDFQGYWALCAGINRAIEEGIHLTSPSYYRNITIDDLKHIFRSETSTEMPLLEERAKNLRETGNILAQTFQNSFAHMILLANKSAKLLLSMVINNFDCFRDDGDFCNQKVSFYKRAQILIADTWACFEGKGFGEFPDIDFLTMFADYKVPQGLYDLGVLQFSEALKQKLVTGQLIPHGDQLEMEIRGNSIWAVEKIYLAVKLKAKKSPEFSNMDSLELAQYLNSVIIDFYLWDFSKNVEARASIPCHKTRTIFY
What is the function of this protein?
Involved in salvaging queuosine.
What are the official names of this protein?
Queuosine salvage protein.
What is the protein family that this protein belongs to?
Belongs to the queuosine salvage protein family.
Protein: PTU3C_STAAN
Sequence: MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVMEAAGQVVFDNLPLLFAVGTALGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAWCYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVLLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGLHHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLKDGVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKVVGGLMLSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVGIVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIKALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGVGQIIPLSEVPDQVFAGKMMGDGIGFIPEKGEIVAPFDGTVKTIFPTKHAIGLESESGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQAQPLMKVNLAYLKAHAPSIVTPMIITNLENKELVIEDVQDADPGKLIMTVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in alpha- and beta-glucoside transport (By similarity).
What are the official names of this protein?
PTS system glucoside-specific EIICBA component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTH_BACFR
Sequence: MKYLIVGLGNIGPEYHETRHNIGFMVLDALARANNLSFTDGRYGFTTTLSVKGRQMILLKPSTFMNLSGNAVRYWMQKENIPLENVLIIVDDLALPFGTLRLKSKGSDAGHNGLKHIATILGTQNYARLRFGIGNDFPRGGQIDFVLGHFTDEDWKTMDERLETAGEIAKSFCLAGIDITMNQFNKK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNT6_SCHPO
Sequence: MDGSDSLLKSVDVSKLDNGSTISFRAREDGFLESISSSSGKLVDMVLDSTSKECLPKFSFQNKLDFYFLFSDRVLQLQKERKVLVLIHCESLQSFDSFFAQKLKYADLISSDNVHEIFLPDSNAANIRYHWEWSPPSGKLLEYECKNYSCIAVYSTEDCTLERISKFSYYTVSRCGDSMDDTFFSESQRVTSPLTTSQTVQTQPPQSPEAKTELSLINTKTVIFPENYEDGPSFRSMLHELEQKSSLMKYYCKKIMKRIVQLSDAYDASQVAVMKLSETLSEASNSTSMNMDILLDSYLTKAMDIHATFIQKLNYDLINLLYEPFHNIYSSFIKPIDDRRLEFDEQSKSFYGSLSRYLSAKKDKKGGDSKFFQKEKTFALQRYDYYCFMQDLHDGSIINDINGIFLQYFHRQYDHIALFSNLMNSVLPNLQQLNLKLEKTKWSTTRRDKGREMHRSQVIQTSGRPKSMAPPSPSPISPSFPLHEIQSPMPNRRMAASADDISQTSNFTTEIKGKCISNGGSASPDKIFKEGLLLVFGATELGTDLAMVSKAAWHKHWIVVENGSLWEYANWKDSVKSNVSSISLKHASADKVRKQGRRFCFEVVTPKLKRLYQATSAEEMDSWIEAICEAAKISSFQLSRVATPLSASVRRPSKVFPLFSTSFETTPISRKLSGSGIKKAFSRKGSWNLQQFFRSDNSGTMHMEQLERYHASANIFIQMLRKTDVSNSVCADCGSVKDVTWCSINIPVVLCIECSGIHRSLGTHISKTRSLLLDSLSQQSKVLLCKIGNAAVNRVYEKGLSNPSLKPKPEHNAQVKLAFAQKKYVEHAFIDFAGVDADATLLEGLEQNKISKILLGLAAKPNFEENGVVFLKAVTRDTSKLHLLELLFMNGLLLPDSEQLSEHVSPDMQSYLSQKQFTKYLKE
What is the function of this protein?
GTPase-activating protein for the ADP ribosylation factor family.
What are the official names of this protein?
Probable ribosylation factor GTPase-activating protein cnt6.
What are the subcellular locations of this protein?
Cytoplasm. Cell tip. Cell septum.
Protein: HRCA_GEOSL
Sequence: MTDISERNKLILEAIIEDYITTAEPVGSRAVTKRHGLTLSPATVRNVMADLEEMGYLVSPHTSAGRVPTDKAYRLYVDSLLAVRRIDKVERERIRKRYAEAGRDIGAVLHETSRLLSSVSHYTGIVLAPRFSATIFRHIEFVKLGGRRILVILVADNGTVQNRLIESDEEFSSEELIRMSNYLNELLVGVPVGQVRTRILEEMRNEKVLYDKLLARALQLSEQSLNDDGAQIFIEGQTNILEQPEFADSRRMRDLFRAFEEKNQLVGLLDRCLNAQGVQIFIGAETHLSQMEGLSIITSTYLTGKNTLGVLGVIGPTRMGYAKVIPIVDYTAKLVSRLLEGE
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RIMB3_MOUSE
Sequence: MTKDSPTPLGGGRASPKKPSSPGPAAAVLEEQRRELEKLRAELEGERARGRSERRRFATQTRQLRESAEQERQQLADHLRSKWEARRLRELRQLQEEVQREREAEIRQLLRWKEAEMRQLQQLLHQERDVVLRQARELQRQLAQELVNRGYCSRSGASEASAAQCRCRLQEVLALLRWETDGEQAARIRHLQAALDVERQLFLKYILEHFRWQPALPGPADPQATHSLEEPPLEAQSNTGGTPKPARRLGSLESLNTGVRVHSPNDLLPTRAGSLESLATAHSCSLDNTLNCSQASESEVRAPATSASIPDTSSPQPPPQLPSIHRKPNDLQKESSENKPCEASTSSPPGLDYQELVRQNSELAEALQVLVRRCCDLREENLHLRRKGFSEEAGEKVKWLKVKHAELTDLAQRLEDRARKLQETNLRAMSAPVPGESLEGLDLSQVFTCQRAQDLSEQAGALQAKDLQIEALRRECHLLQARIAADLGSSSHPEEGATCAQWCNISDLDRLQRESQREVLRLQRQLTLHQSKAGAWADAGRPSTPSEITRHQVQALERELGLQRRECEELSVQAAAAERRYEETEAQLQAALHKGARLSEENARLQALANWMKKMADENSNVSRQQSHTRQRQELEATSLLAEQLLQQEGYAQDRRQQLQHYKNKALSDLRTSGKEMQGLQFQPGHPSETSETTQASESQARDSGRPTFKTKSEERVLPLPTRDIQPPACLSQQENPVIVEEPAAGPQVSDRNSTSQSLDSKPQAKKTSSQSNSSSEVESMWATVPSCLSLDMDTASEVDDLEPDSMSTPLEMRSLEAPIIPKLKLFLARSSYNPFEGPSEHCQGKLPLTAGDYVYVFGDMDEDGFYEGELVNGQRGLVPSNLVEPISGSPILNHLFLKSPDIGPTALPAGHSKVLKKGSLLLGEVQERGLCQVGRVDSKTDMAAESLKTKTEACWLGLKSSLEEQSFSRPLLEAKGAFCLAPMELQLQNVTATSATITWASGSNRYPHVVYLDDEEHILTPSGVNHYTFQGLHPGTCYRVRVGVQLPRDLLQVLWETTSSTLTFDTPLAGPPDPPLDVLVEHHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYVDGFKVTEVADATAGNTLLEFSQLQVPLSCQKVSVRTMSLYGESLDSVPAQIPEDFFSCCPFLGAPPFNYTDGNPFPVCHQKLVQASLGAKSSPRGPGNCGEPQAKFLEAFPEEHPRKHLSLSSLSSDGTNSQAQGPTEAWKGYEKDLSFQKSPQNHKPPLLFGQSGVEEGHAPHICISGSPAPGFVHLSSEIGHGKIRCWEKPGLEKALLQNQYAPMVPPHQQGSSQCQPADFHHVFEEKEALCLDSQGTEKPEQRKNKSQNGQRQGTPGSKRECSVLCPAPTNKVIKMTSGSPDQLETDANNPVRVFLALFDHSPLVISVNSEAAEEELAFQKGQLLRVWGSLDLHGFYHGECNGHLGKIPGHLVVEVEVGTQQTDGRWHLPAQGHLLSETQREDLEGLTNSQGSYMPQGNSRTPTLWTPKTMVAALDYDPRDGRAGVQAKGKLVLRAGDVVTVYGPVDDKGFYYGEYGGHRGLVPAHLLDDLPVHGE
What is the function of this protein?
Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development (PubMed:19091768, PubMed:28003339).  Important for male fertility (PubMed:19091768).
What are the official names of this protein?
RIMS-binding protein 3, RIM-BP3.
What is the protein family that this protein belongs to?
Belongs to the RIMBP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=In elongating spermatids, localizes to the manchette.
Protein: GLND_CHRVO
Sequence: MTLSAAPLQHWRQTLAEKRQQLADAYRADRDAPAFLRRYSQAVDQTLAALWREQGLDGQAALAAVGGYGRGQLFPCSDVDILILLPDPTPAEINDKVSHFIGLMWDIGLEIGHSVRTLDECLREAAGDITIETNLLENRLVAGPAEPWRELMRRLEAQRDPLAFFEGKTLEQQQRHTRHFGVSNNLEPNLKESPGGLRDLHTILWISKAAGLGDNWDSLVRRGILTLAEARLIKHSEEQLQKLRVDLHLLARRREDRLIFDLQQQVAQAWGLADTPAKRASEQLMQLYFRAAKTVNQLNGILLPNLRGRIYCQVPRVTQHISEYFHAVNGMLGIREVNVFDKHPHAILEAFLTLQRHPELSGFAPRMLRALWHGRSQINDRFRSDPRNRATFMQIFREPSGLTRTLRRMNLYGILGQYLPNFGQIVGQMQHDLFHVYTVDEHILMVVRNLRRFAISAYNHEYPFLSRLINDFERPEVLYLAGLFHDIAKGRGGDHSQLGIADADAFCRDHGLAEEDCQLVAWLVGQHLTMSSIAQKQDIYDPETVQRFAELVRTPRRLAALYLLTVADIRGTSPKVWNTWKAKLLEDLYHATLRVLSRGGEIDLASELEARKNQARAQLRLHAIPDAAEAGLWAQLDTVYFLRHEAKEIAWHARVLNRQLSPDTPQVRARLADDHEGLQVLIYSPDKPELFARACAFFGRTNYSIADAKVYTTRHGYALDTFHVFVPEHHDGDYRDMINFIEFELAAALATDQPLQLPPQGRISRHLKHFPITPQVSIRPDDKDSDFILSIVAGDRPGLLARIAKVLADYRLNVRSAKIMTLGGRAEDSFQVSGAALKDDKTALALEAALITALRI
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: PIP26_ARATH
Sequence: MTKDELTEEESLSGKDYLDPPPVKTFEVRELKKWSFYRAVIAEFIATLLFLYVTVLTVIGFKSQTDINAGGGACASVGLLGISWAFGGMIFILVYCTAGISGGHINPAVTFGLFLASKVSLVRAVSYMVAQCLGATCGVGLVKVFQSTYYNRYGGGANMLSDGYNVGVGVGAEIIGTFVLVYTVFSATDPKRNARDSHIPVLAPLPIGFSVFMVHLATIPITGTGINPARSFGAAVIYNNQKAWDDQWIFWVGPFVGAAIAAFYHQFVLRAGAMKAYGSVRSQLHELHA
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Probable aquaporin PIP2-6, Plasma membrane intrinsic protein 2-6, AtPIP2;6, Plasma membrane intrinsic protein 2e, PIP2e.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FBK38_ARATH
Sequence: MASISETSDDGSNGGVPNQKPEEPHKNPQEEKENQNENPNEADEEDDHQDEEVENVPPIPRKIPPVLIENTIAPLRRCHYPKLSLLSNAFRQVISSEDLFQVRSLIGSTEPVLYTLITFKYPTFEEGRWFILQRRNNTSLKLNCVTSLPPMFLGCTAVTIGHKIYVVGGYNFRYNKTISTVLEIDCRFNTCRHLRNMKRDRCSAVAGVIDGRIYVVAGRQRRFDDWVEVFDVETERWELVPGPFSSFASSSGKFIVHVVLDNKIYIMDGDYCFAYDPRRRRWETWGPESAQRSYWHLSSCVVDDLLYAIVPREIFGASIVVYDPRGIAWRPVMGLEFWPNLVYFESKMANFGGKLVILGCYRSSFDYYRKDVWCVEVALEKHEDGQIWGKVESLSLVNAFPMSPFFELSRTVTI
What are the official names of this protein?
Putative F-box/kelch-repeat protein At2g29800.
Protein: FADR_SHIFL
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_CAMJE
Sequence: MDRIVEIEKYSFDETYETSLRPSNFDGYIGQESIKKNLNVFIAAAKKRNECLDHILFSGPAGLGKTTLANIISYEMSANIKTTAAPMIEKSGDLAAILTNLSEGDILFIDEIHRLSPAIEEVLYPAMEDYRLDIIIGSGPAAQTIKIDLPKFTLIGATTRAGMLSNPLRDRFGMQFRLEFYKDSELALILQKAALKLNKTCEEKAALEIAKRSRSTPRIALRLLKRVRDFADVNDEEIITEKRANEALNSLGVNELGFDAMDLRYLELLTAAKQKPIGLASIAAALSEDENTIEDVIEPYLLANGYIERTAKGRIASAKSYSALKLNYEKTLFEE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: LTO1_ARATH
Sequence: MMARFVSVSSCQFHFGFREVSPPSVTSYPRRFEVSDRRFPAIPIKCSSSEPENGEDSAPSLSSSSSSSTSEVSTSNSSTYNWYTGIGGIGMLDTAYLTYLKVTGSDAFCPIGGGTCGDVLNSDYAVVFGVPLPVIGFVMYGVVTALSAELGEGNLPFGISKSNGRFALFGITTAMASASAYFLYILSTKLSGSSCLYCLVSAFLSFSLFFLSVKDVKLQEIQQVVGLQICLAIIVVASLTASYSTAQPIPSRSGDIELPYFRTEISSSSSPYAIALAKHLNSIGAKMYGAFWCSHCLEQKEMFGREAAKELNYVECFPDGYKKGTKILKACADAAIEGFPTWIINDKVLSGEIELAELAEMTGFSLDQANETNQLQ
What is the function of this protein?
Thiol-disulfide oxidoreductase catalyzing disulfide bond formation of chloroplast proteins and involved in redox regulation and photosynthetic electron transport.  Required for the assembly of photosystem II (PSII) through the formation of disulfide bond in PSBO, a subunit of the PSII oxygen-evolving complex in the thylakoid lumen.  Involved in the formation of disulfide bonds in the lumenal protein FKBP13.  In vitro, reduces phylloquinone (vitamin K1) and menaquinone (vitamin K2) to their respective quinol.  Cannot reduce phylloquinone epoxide to phylloquinone (PubMed:20626653, PubMed:21781282, PubMed:22209765, PubMed:23689258).  Plays an important role in regulating the thylakoid lumen redox (PubMed:25412899).
What are the official names of this protein?
Thiol-disulfide oxidoreductase LTO1, Protein LUMEN THIOL OXIDOREDUCTASE 1, Vitamin K reductase.
What is the protein family that this protein belongs to?
Belongs to the VKOR family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FUT1_RAT
Sequence: MWTPSRKQLCLAFLSVCVLSAGSFFFHLNGGNFFQNALTFSVLCPDYHLLKSPVAMVCLPYPSNASSGSPSCPEQSLLSGTWTITPGGRFGNQMGQYATLLALAQLNGRRAFIQPEMHTTLAPVFRISLPVLDPEVDSLTPWQHLVLHDWMSEEYSHLEDPFLKLSGFPCSWTFFHHLREQIRREFTLHDHLREDAQRLLSGLRIGPAGIRPRTYVGVHVRRGDYLEVMPNRWKGVVGDRAYLQKAMDWFRARHKDPIFVVTSNGMRWCLENIDTSHGDVVFAGNGQEGTPGKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEFLKIFRPKAAFLPEWVGINADLSPLQAQFDPWETDSLFRLA
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens.  H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis (By similarity).  Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a (By similarity).
What are the official names of this protein?
Galactoside alpha-(1,2)-fucosyltransferase 1, Alpha 1,2-fucosyltransferase A, Alpha(1,2)FT 1, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: PHRF1_HUMAN
Sequence: MDDDSLDELVARSPGPDGHPQVGPADPAGDFEESSVGSSGDSGDDSDSEHGDGTDGEDEGASEEEDLEDRSGSEDSEDDGETLLEVAGTQGKLEAAGSFNSDDDAESCPICLNAFRDQAVGTPENCAHYFCLDCIVEWSKNANSCPVDRTLFKCICIRAQFGGKILRKIPVENTKASEEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAAPGVVLAADAGPVSEEEVSLLLADVVPTTSRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHTPGRLGSSLLDEAIEAVATGLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTRSRIARTLGLRRPVHSSCIPSVLKPVEPSLGLLRADIGAASLSLFGDPYELDPFDSSEELSANPLSPLSAKRRALSRSALQSHQPVARPVSVGLSRRRLPAAVPEPDLEEEPVPDLLGSILSGQSLLMLGSSDVIIHRDGSLSAKRAAPVSFQRNSGSLSRGEEGFKGCLQPRALPSGSPAQGPSGNRPQSTGLSCQGRSRTPARTAGAPVRLDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTNKHTLPLASAASKISSRDSKPPCRSVVPGPPLKPAPRRTDISELPRIPKIRRDDGGGRRDAAPAHGQSIEIPSACISRLTGREGTGQPGRGTRAESEASSRVPREPGVHTGSSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAPPVLEVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQEPHLLRPDAAEKAEAPSSPDVAPAGKEDSPSASGRVQEAARPEEVVSQTPLLRSRALVKRVTWNLQESESSAPAEDRAPRAPLHRPQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLPPAPAQPSSIPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPASEPASQATAASNSEEKTPAPRLAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVKAYVDKYRHMRRHKKPEAGEEPPTQGAEG
What are the official names of this protein?
PHD and RING finger domain-containing protein 1.
Protein: ADEC_METMJ
Sequence: MDFGVKDGRIIGFGEYRGTREYDLSGAYVVPGLIDAHVHIESSLLAPAEYARLVLAHGTTTVIADPHEIANVCGAPGIDYMLAQGARTPLDILVMLPSCVPATPFDAGGAVLTAADLARFRGREGVVGLAEVMNVPGVLFGDEDLRAKMDLFEVVDGHAPFLSGKDLNAYIYAGVQSDHECTALPEAREKLLRGMYVMIREGSTERNLHDLLPLVDACTAPRCCFATDDRHADMLAGEGHIDDCVRKAVSGGLEVEQALRMATLSAAGRFGLHDRGALAPGRLADFCVADDPDRFRVLRTFKRGVEVVDAGYLPPACPKSPMHARVPEPGDIRITGRGEARVIEIVPGQITTRDLRYPVDAAGIPDLDRDILKAVVIDRYRATGSGVGLVHGFHLQEGAIAGSVSHDSHNIVAVGAGDADIVRAVAEVVRLGGGLAVVSGDDITALPLECAGLMSALPYDEVVRRLAALEEHARRLGAIANPFMYLSFLALTVIPEVRVTERGVFDVGAFTDVPLFEE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: GLMM_BURTA
Sequence: MGRRYFGTDGIRGKVGDAPITPDFVLRLGYAAGKVLASAPGRAASGARPTVLIGKDTRVSGYMLEAALEAGFSAAGVDVMLAGPMPTPGVAYLTRALRLSAGVVISASHNPYHDNGIKFFSADGNKLPDETEAEIEAWLDKSLDCAPSDGLGKARRLDDAAGRYIEFCKSTFPAAFDLRGMKLVVDCAHGAAYQVAPHVFHELGADVIPIGVAPNGFNINDGVGATAPDALMRAVRANHADLGIALDGDADRLLVVDHTGRLYNGDELLYVLVKDRIATNGQVEGAVGTLMTNLAVEVALKDAGVQFVRAAVGDRYVLEQLRERGWQLGAEGSGHILSLDRHSTGDGIVSALLVLAALKRSGKTLAQMLEGVTLFPQKLINVRMKPGADWKGSDAIRRAIGSAEQALAGSGRVLIRASGTEPVLRVMVEARHAADANHHAEAIADAVKQATA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.