PharMolix/UniProtQA huggingface dataset:
Protein: RNC_AGRRK
Sequence: MTKTPTLSQADRLTLEAAIGHAFVEKERLDWALTHASARTHKAGNYERLEFLGDRVLGLCIAELLFRTFGTATEGELSVRLNQLVSAETCAAVADEMQLHLFIRTGADVKKLTGKRMLNVRADVVESLIAALYLDGGLEVARKFILRYWEGRAVRPDGARRDAKTELQEWAHAKFGVTPVYRVDDRSGPDHDPRFTVTVEVAGAAPETGIERSKRAAEQVAATRILEREGIWQPQSAQK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_BACVZ
Sequence: MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGNNAGHTIKFDGVTYKLHLIPSGIFYKEKACVIGNGMVVDPKALITELAYLHERNVSTDNLRISNRAHVILPYHLKLDEVEEERKGANKIGTTKKGIGPAYMDKAARIGIRIADLLDRDVFAEKLERNLEEKNRLLEKMYETEGFKIEDILDEYYEYGQQIKKYVCDTSVVLNDALDEGRRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPTKIQHVVGVSKAYTTRVGDGPFPTELKDEIGDQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGITDLSLNSIDVLTGIETLKICVAYRYKGEVIEEFPASLKALAECEPVYEEMPGWTEDITGAKTLSDLPENARHYLERVSQLTGIPLSIFSVGPDRSQTNVIRSVYRAN
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 9DC2_SOLPI
Sequence: MGCVKLVFFMLYVFLFQLVSSSSLPHLCPEDQALALLQFKNMFTVNPNAFHYCPDITGREIQSYPRTLSWNKSTSCCSWDGVHCDETTGQVIALDLRCSQLQGKFHSNSSLFQLSNLKRLDLSNNNFIGSLISPKFGEFSDLTHLDLSDSSFTGVIPSEISHLSKLHVLLIGDQYGLSIVPHNFEPLLKNLTQLRELNLYEVNLSSTVPSNFSSHLTTLQLSGTGLRGLLPERVFHLSDLEFLDLSYNSQLMVRFPTTKWNSSASLMKLYVHSVNIADRIPESFSHLTSLHELDMGYTNLSGPIPKPLWNLTNIESLDLRYNHLEGPIPQLPIFEKLKKLSLFRNDNLDGGLEFLSFNTQLERLDLSSNSLTGPIPSNISGLQNLECLYLSSNHLNGSIPSWIFSLPSLVELDLSNNTFSGKIQEFKSKTLSAVTLKQNKLKGRIPNSLLNQKNLQLLLLSHNNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHLDLSKNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMINCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLRSNKLHGPIKSSGNTNLFMGLQILDLSSNGFSGNLPERILGNLQTMKEIDESTGFPEYISDPYDIYYNYLTTISTKGQDYDSVRILDSNMIINLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHLVGCIPKGKQFDSFGNTSYQGNDGLRGFPLSKLCGGEDQVTTPAELDQEEEEEDSPMISWQGVLVGYGCGLVIGLSVIYIMWSTQYPAWFSRMDLKLEHIITTKMKKHKKRY
What is the function of this protein?
Involved in plant defense.  Confers resistance to the fungal pathogen C. fulvum through recognition of the AVR9 elicitor protein.
What are the official names of this protein?
Receptor-like protein 9DC2.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NV_HIRRV
Sequence: MNSKTPSTDIAALKDLLRYKVTVARHGFLFDDGKIVWSEDGDEAWNRLLVVVGALRSSNRMSQALFMDMSITKGDGYLLFSDLQGTNNLQYRTPKFRQYLFPVDEFLPLPR
What is the function of this protein?
Plays an essential role for the viral pathogenicity.
What are the official names of this protein?
Non-virion protein.
What is the protein family that this protein belongs to?
Belongs to the novirhabdovirus NV protein family.
Protein: HSP1_TRAJO
Sequence: MARYRRCRSQSRSRCCRPRRRCRRRRRQSCRARRRATRCCRRRYRLRCRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: C71BW_ARATH
Sequence: MAHIWLLPLIFLVCILLAVFNHKKHPKYRQFPCPPGFPIIGNLHQIGELPHQTLWKLSKKYGPVMHLMLGRVPTVVVSSSDTARQVLRVHDLHCCTRPSLSGPRELSYNYLDIAFSPYDDYWKEVRKLCVQELFSTKQVHSIQPIKDEEVKKMIDSIAESASQKNPVNLNNKCLELTVSVVCRTAFGVSFEGTVLNSDRFNKIVREALEMLGSFSAADFIPYVGWIIDVLTGLQGRRERSKRDLNAFFEQMFDLHKEGKKEGNEDFVDLLLRLEKEEAVLGNDKLTRNHIKAILLDVLLAGIDTSAITMTWAMTELARNPRVMKKVQSEIRTQMGNRSMISFEDMDQLEYLKMVIKETWRLHPTTPLLLPREAMSEFDINGYTIPVKTRLHVNVWAIGRDPDTWKDPEVFLPERFMDNNIDAKGQHFELLPFGGGRRICPAIYMGTTMVEFGLANLLYHFDWKLPEGVEVKDIDVEEAPGLTVNKKNELLLVPEMRRSCG
What are the official names of this protein?
Cytochrome P450 71B35.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YGFZ_VIBPA
Sequence: MEWQTRFSPLNLSTQDALPELSISRLDHLGMITMVGDDKKSYLHGQVTCDVVSLEKDQSTLGAHCDAKGKVWSVFRLFHHGDGYGMIQPKSAIEIELKEIKKYAVFSKVTIEESNDVILGVAGVNADAFVSALNEDAGDVRIINGGTAVKVEANRWLLVVTEEAAQALIENSDATLTTRELWTRFDIESALPFVSATAQNEHIPQALNIQALGGISFTKGCYTGQETVARAKYRGTNKRAMYIVKGVTSTALNDDAIELERSVGDNWRSVGTLLTHYQFSDNQAMGLIVLPNNLDDDTRLRLTSQPDCEWTIAELPYSLDDE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTAA_STAS1
Sequence: MFSKKNLKWLSVLATVIMAFVQLGGALVTKTGSADGCGSDWPLCHGAFLPQNLPIQTLIELSHRAVSGLSLIVVLWLVIVAWKHIGYIKEVKPLSCISVGFLLIQALVGAAAVMWQQNAYVLALHFGISLISFSSVFVLTLIIYEVDRKYEADELFIRKPLRIYTWIMALIVYMTIYTGALVRHKEASLAYGQWPLPFNDLMPHNVQDWVNLTHRGMALIAFIWILITFIHAVNNYRENRTIRYGYTAAFILVILQVTTGALSIITEVNLFIALLHALFITLLFGLIAYFIILMLRTIRSGG
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLGB_SHIBS
Sequence: MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICGLPEKVVQTEERKKANQFDASISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLTFGILYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RS2_HELPY
Sequence: MVTMKDLLECGVHFGHQTRRWNPKTKKFIFGVRKNIHIIDLQKTLRYFRYTYNIVRDASAQGKSIMFVGTKKQANETLKEFAESIQVPYVNYRWLGGMLTNFSTIRKSVRKLEIIEEMENSGQIDLLTKKEKLMILRKKEKLDKYLGGVRHMKKIPDMIFVIDVAKEKIAVAEARKLHIPIVAPLDTNCDPDLVDYPIPGNDDAIRSIRLFCKEMSEAILEGRELMQEEIVHANENSEEIEYVSHEEKEEMLAEIQKEITQGAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: YV007_HUMAN
Sequence: MTRNVVRQEFEAPGKPQDSSQQDACLILVKGNWTTNEMEVK
What are the official names of this protein?
Putative uncharacterized protein MGC15705.
Protein: ARNF_SHISS
Sequence: MGLMWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFGLDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFSLKALLGVACIMSGLMLIFLPTTKQRY
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYQ_VIBPA
Sequence: MSEADARPSNFIRQIIDKDLADGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPEKEDIEYVESIKKDVNWLGFEWDGEVCYSSNYFDKLYEYAIELINKGLAYVDELSPEQIREYRGTLKEPGKPSPYRDRSVEENLALFEKMRAGEFEEGKACLRAKIDMGSSFMVMRDPVLYRVRFATHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFMDNRRLYDWVLDNITIDCRPHQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTVSGLRRRGFTPASIREFCKRIGVTKQENMIEFSSLESCIRDDLNENAPRAMAVLDPVKVVIENFEVGAVENLTLANHPNKPEMGEREVPFTREVWIEREDFREEANKKYKRLVLGKEVRLRGAYVIKAERVEKDAEGNITTIYCTYDPETLGKNPADGRKVKGVIHWVSADKALPAEIRLYDRLFTVPNPAAAEDFASTINTDSLVVINGFVEPSLASAEAEQGYQFERMGYFCADSKDSTADNLVFNRTVGLRDTWAKIENQ
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTCP2_HUMAN
Sequence: MNDPNSCVDNATVCSGASCVVPESNFNNILSVVLSTVLTILLALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVSLVVPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK
What is the function of this protein?
Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine (PubMed:7592981, PubMed:9458785, PubMed:9856990).  Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate (PubMed:7592981, PubMed:9458785, PubMed:9856990).  Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable).  Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation (PubMed:33222321).
What are the official names of this protein?
Ileal sodium/bile acid cotransporter, Apical sodium-dependent bile acid transporter, ASBT, Ileal Na(+)/bile acid cotransporter, Ileal sodium-dependent bile acid transporter, IBAT, ISBT, Na(+)-dependent ileal bile acid transporter, Sodium/taurocholate cotransporting polypeptide, ileal, Solute carrier family 10 member 2.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CLPX_BURO1
Sequence: MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEASLSRSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQVDTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLRETEPEDLIKFGLIPELIGRLPVVATLGKLDEAALMKILVEPKNALVKQYHKLFAMERVELEIRPGALQAVARKAIRRKTGARGLRSIIEQALLDVMYELPTMKGVSKVIIDENVIDGDGKPLLIYEDTPKVAGSN
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: XPO2_PAGMA
Sequence: MELNDANLQTLTEFLRKALDPDPTVRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNVIRVCAAVTFKNYIKRNWRVIEDEPNKVSDPDRTAIKANIVNLMLSSPEQIQKQLSDAISIIGREDFPQKWPDLLTEMVTRFRSGDFHIINGVLRTAHSLFKRYRHEFKSNELWSEIKLVLDTFALPLTELFKATIELCQTHATDVNALKVLFSSLTLISKLFYSLNFQDLPEFFEDNMETWMTNFHGLLTLDNKLLQTDDEEEAGLLELLKSQICDNAALYAQKYDEEFQPYLPRFVTAIWNLLVSTGQEVKYDLLVSNAIQFLASVCERPHYKHLFEDQNTLTSICEKVIVPNMEFRSADEEAFEDNSEEYIRRDLEGSDIDTRRRAACDLVRGLCKFFEGPVTAIFSGYVNSMLAEYAKNPGENWKHKDAAIYLVTSLASKAQTQKHGITQANELVNLNEFFVNHILSDLKSHNVNEFPVLKADAIKYVMIFRSQLPKEQLLQAVPLLISHLQAESTVEHTYAAHALERLFTMRGPNNTTLITPVEMAPFTEQLLNNLFKSLALPGSAENEYIMKAIMRTFSLLQEAIVPYIPTLIGQLTHKLLLVSKNPSKPHFNHYLFESLCLSVRITCKANPATVSSFEEALFPVFTEILQNDVQEFLPYVFQVMSLLLEIHSSSIPSSYMALFPHLLQPALWERTGNIPPLVRLLQAYLEKGGATIAASAADKIPGLLGVFQKLIASKANDHQGFYLLNSIIEHMPPESITQYRKQIFILLFQRLQSSKTTKFIKSFLVFVNLYSVKYGAIALQEIFDSIQPKMFGMVLEKIIIPEVQKVSGAVEKKICAVGITKVLTECPAMMDTEYTKLWTPLLQALIGLFELPEDDSIPDDEHFIDIEDTPGYQTAFSQLAFAGKKEHDPIGDAVGNPKILLAQSLHKLSTACPGRVPSMLSTSLNAEALQFLQGYLQAATVQLV
What is the function of this protein?
Export receptor for importin alpha.  Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity).  Negatively regulates fluid secretion and plays a role in fluid homeostasis by down-regulating cftr activity (By similarity).
What are the official names of this protein?
Exportin-2, Exp2, Cellular apoptosis susceptibility protein, Chromosome segregation 1-like protein, Importin-alpha re-exporter.
What is the protein family that this protein belongs to?
Belongs to the XPO2/CSE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: MNMA_STRT2
Sequence: MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDEFGVCTATEDYKDVAAVADQIDIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYAQVVRDEDGIVHMLRGADNNKDQTYFLSQLSQEQLQKTMFPLGHLQKPEVREIAERAGLATAKKKDSTGICFIGEKNFKEFLSQYLPAQKGRMMTIDGRDMGEHNGLMYYTIGQRGGMGIGGQKGGDNAPWFVVGKDLSKNILYVGQGFHHESLMSTSLDASMIHFTRDMPEEFEMECTAKFRYRQPDSKVTVKVKGDKSEVIFAEPQRAITPGQAVVFYDGQECLGGGIIDQAYKDGKVCQYI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_YERP3
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKSRSRLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: GRPE_STAAT
Sequence: MTNKDESVEKNTESTVEETNVKQNIDDSVEQAEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EHAA_METKA
Sequence: MKDPGLVAVGVAAAVAFGTALALGLPPIQRDKPRRKSWEVSAAFPTPVIAAGATVLVIRVIGYHPPIPLAIVGAVVGALSAAFTAYIEKVFPRPEAG
What is the function of this protein?
One of the integral membrane subunits of multisubunit membrane-bound [NiFe]-hydrogenase eha.  Eha is predicted to form large electron transfer complex and might catalyze energy-driven reduction of low-potential redox carriers (By similarity).
What are the official names of this protein?
Probable [NiFe]-hydrogenase-type-3 Eha complex membrane subunit A.
What is the protein family that this protein belongs to?
Belongs to the EhaA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DDX55_CAEBR
Sequence: MTSKVGAVATKTYREKLGPEILEVFDKSYKSFTDVQVLAGTHLLNLSDVVVESPTGSGKTLAFVLPMMRMIQNARLQPNEIGALILSPSRELCSQIVNVIKPFAEKMKLNVETVTGGQKVDKNIKMFKNKDINILVATPGRLFQIIQHEKTMIARAMKGVQLLVIDEADRFNEIQFEDHMREILSCIPKQRRTGLFSATQVKEEDDLMVFGLRNAKQVKVSQERNSAAPSTLKNYFVECPADEKTSVCLEFIRQRTDKKVLIFFPSCNSVRYFHKIFERCLTKRPLFAVHGKCSNPHRAAQIKAFSESTNGVMISTDVMARGIDITDIDWVIQYDLPKHSSWFVHRAGRTARCGRDGNALILIATEQLAYVSFLDNHEKVKLEEVKVPTSTSRKAEELRQKMIKIQVSDRAILELGTRAFVSHIESYAKHDCHLICSLDDLNVVGLANSYALLRLPKMRELAQRKDLNQFDRSDIETSEIKYADPKLEANRDTVMKEKHEKKIETLAAKEKKRREKEARKMKRAGGRFKSRATGANAEEKRAKKRKSEEEDDAQNDIRLLKKIKRGKLSKKEIKDVL
What is the function of this protein?
Probable ATP-binding RNA helicase.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX55 homolog, DEAD box protein 55.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
Protein: EFTU_STRPM
Sequence: MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAGDNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGIVSEIEA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAL7_HYPJE
Sequence: MPDKILDDISHRRYNPLTDSWLLVSPHRTKRPWQGQQEGAAVTTLPEYDPKCYLCPGNSRAAGDQNPNYEQTFAFVNDYSAVKEQQPDYEVDQSSDDLESLLLRAQGVKGVCYVLTFSPKHNVTLADMSAKDILPTINHWTRLYANHLSPSNPLSAVAAQLQLPISKEEAPVPKDNYRYMQIFENKGAAMGCSNPHPHCQAWTTSTMPEEPGKELVQMAKYRQQHGRHLLADYIKLELAKEERVVWQNDSFVVVCPWWAIWPFEVLVLPKRHVRALVDLTADERLQLAEAIQEVTRRYDNLFECHFPYSSGIHQAPLDGTPEEIENAYFHMHFYPPLLRSATVKKFLVGFELMAEAQRDITPEQATIRLRACDGELYRNKLS
What is the function of this protein?
Essential for growth on galactose but not for cellulase induction.
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Protein: HEMA_INCMI
Sequence: AEKIKICLQKQVNSSFSLHNGFGGNLYATEEKRMFELVKPKAGASVLNQSTWIGFGDSRTDKSNPNFPRSADVSVKTANKFRSLTGGSLMLSMFGPPGKVDYLYQGCGKHKVFYEGVNWSPHAAIDCYRKNWTDIKLNFQKNIYELASQSHCMSLVNALDKTIPLQATAGVAGNCNNSFLKNPALYTQEVTPPEKCGKENLAFFTLPTQFGTYECKLHLVASCYFIYDSKEVYNKRGCDNYFQVIYDSSGKVVGGLDNRVSPYTGNTGDTPTMQCDMLQLKPGRYSVRSSPRFLLMPERSYCFDMKEKGLVTAVQSIWGKDRKSDYAVDQACLSTPGCMLIQKQKPYTGEADDHHGDQEMRELLSGLDYEARCISQSGWVNETSPFTEEYLLPPKFGRCPLAAKEESIPKIPDGLLIPTSGTDTTVTKPKSRIFGIDDLIIGLLFVAIVEAGIGGYLLGSRKESGGGVTKESAEKGFEKIGNDIQILRSSTNIAIEKLNDRITHDEQAIRDLTLEIENARSEALLGELGIIRALLVGNISIGLQESLWELASEITNRAGDLAVEISPGCWIIDNNICDQSCQNFIFKFNETAPVPTIPPLDTKIDLQSDPFYWGSSLGLAITTPISLAALVISGIAICRTK
What is the function of this protein?
Binds to the N-acetyl-9-O-acetylneuraminic acid residues on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HEF2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.  Displays a receptor-destroying activity which is a neuraminidate-O-acetyl esterase.  This activity cleaves off any receptor on the cell surface, which would otherwise prevent virions release.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell (By similarity).
What are the official names of this protein?
Hemagglutinin-esterase-fusion glycoprotein, HEF.
What is the protein family that this protein belongs to?
Belongs to the influenza type C/coronaviruses hemagglutinin-esterase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: RL18_MESH7
Sequence: MQKSRNYYRKVKHVRILKKLKSNREDKQKYRIGVYKSLRNFYAYIFDPWKNKVITSVSTLDKSNGYKGNIVSASSLAPDLYKKMKKLNLENESYIFDRSGYLFHGRVKAFANALRDQGVKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.