PharMolix/UniProtQA huggingface dataset:
Protein: GATB_BORBR
Sequence: MNWEIVIGLETHTQLSTDSKIFSGSSTRFGAAPNTQANAVDLALPGSLPVMNRGAAERAILFGLAVGGKVAPRSVFARKNYFYPDLPKGYQISQYELPVVEGGTLSFFVGEEEKTVNLTRAHLEEDAGKSLHDEFSLASGAPASGIDLNRAGTPLLEIVTEPEMRSAAEAVAYARALHSLVVWLGICDGNMQEGSFRCDANVSVRPVGQKEFGTRTEIKNVNSFRFLERAILFEARRQIELIEDGGTVVQETRLYDADRDETRSMRSKEDAHDYRYFPDPDLPPLVIGQDWVDAVRAGMPELPAAQRARFEADYGLPAYDAAQLTVSRAMADYFEAVARALPAGQAKLAANWIMGEVAATLNREEKDIDAAPVSAAALAALINRIIDGTISNKIARDVFAAMWAGENGGDADAIIAARGLKQISDSGAIGAMIDEVLAANPAIVEEYRAGKQKAFNSLVGQIMKAAKGKANPQQVNELLKEKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: QUEC_PSEP1
Sequence: MTEKRAVILLSGGLDSATVVAMAKAEGYSCYTMSFDYGQRHRAELNAAARVAHDLGVVEHKVIGLNLDGIGGSALTDSSIDVPEAPGEGIPVTYVPARNTVFLSLALGWAEVLEARDIFIGVNAVDYSGYPDCRPEFVEAFERMANLATKAGVEGQGFRIQAPLQNMSKAQIVQAGMARGVDYSLTVSCYQADDDGRACGKCDSCRLRADGFKAAGIEDPTRYF
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: CEMA_TOBAC
Sequence: MAKKKAFTPLFYLASIVFLPWWISFSVNKCLESWVTNWWNTGQSEIFLNNIQEKSLLEKFIELEELLFLDEMIKEYSETHLEEFGIGIHKETIQLIKIQNENRIHTILHFSTNIICFIILSGYSILGNEKLVILNSWAQEFLYNLSDTVKAFSILLLTDLCIGFHSPHGWELMIGSIYKDFGFVHNDQIISGLVSTFPVILDTIFKYWIFRYLNRLSPSLVVIYHSMND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: PNC2B_XENLA
Sequence: MGGGERFNIPGQHRNNLGKQIARQKLFDRNNQKMSMSHTKDRSRGCGTSLAWQAMQNGVNNNTLSSNQNWSAGFPASNNLFTNQDNQNYAGAKFSEPPSPSVLPKPPSHWVLLSCSPAEKELMSFQLKTLLKVQA
What is the function of this protein?
Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.  May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs.  Required for upf1/rent1 localization to the P-body.  Also acts as a nuclear receptor coactivator (By similarity).
What are the official names of this protein?
Proline-rich nuclear receptor coactivator 2 B.
What is the protein family that this protein belongs to?
Belongs to the PNRC family. PNRC2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, P-body.
Protein: Y064_MYCTO
Sequence: METGSPGKRPVLPKRARLLVTAGMGMLALLLFGPRLVDIYVDWLWFGEVGFRSVWITVLLTRLAIVAAVALVVAGIVLAALLLAYRSRPFFVPDEPQRDPVAPLRSAVMRRPRLFGWGIAVTLGVVCGLIASFDWVKVQLFVHGGTFGIVDPEFGYDIGFFVFDLPFYRSVLNWLFVAVVLAFLASLLTHYLFGGLRLTTGRGMLTQAARVQLAVFAGAVVLLKAVAYWLDRYELLSSGRKEPTFTGAGYTDIHAELPAKLVLVAIAVLCAVSFFTAIFLRDLRIPAMAAALLVLSAILVGGLWPLLMEQFSVRPNAADVERPYIQRNIEATREAYRIGGDWVQYRSYPGIGTKQPRDVPVDVTTIAKVRLLDPHILSRTFTQQQQLKNFFSFAEILDIDRYRIDGELQDYIVGVREFSPKSLTGNQTDWINKHTVYTHGNGFVAAPANRVNAAARDAENISDSNSGYPIYAVSDIASLGSGRQVIPVEQPRVYYGEVIAQADPDYAIVGGAPGSAPREYDTDTSKYTYTGAGGVSIGNWFNRTVFATKVAQHKFLFSREIGSESKVLIHRDPKERVQRVAPWLTTDDNPYPVVVNGRIVWIVDAYTTLDTYPYAQRSSLEGPVTSPTGIVRQGKQVSYVRNSVKATVDAYDGTVTLFQFDRDDPVLRTWMRAFPGTVKSEDQIPDELRAHFRYPEDLFEVQRSLLAKYHVDEPREFFTTNAFWSVPSDPTNDANATQPPFYVLVGDQQSAQPSFRLASAMVGYNREFLSAYISAHSDPANYGKLTVLELPTDTLTQGPQQIQNSMISDTRVASERTLLERSNRIHYGNLLSLPIADGGVLYVEPLYTERISTSPSSSTFPQLSRVLVSVREPRTEGGVRVGYAPTLAESLDQVFGPGTGRVATXPGGDAASAPPPGAGGPAPPQGVPPPRTTQPPAAPPRGPDVPPATVAELRETLADLRAVLDRLEKAIDAAETPGG
What are the official names of this protein?
UPF0182 protein MT0070.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURA1_LATSS
Sequence: MEKLIIQGGQPLVGDVHIEGAKNAVLPIMAAALLASKGPVELTNVPILSDVFMMQDVLKSLDARVKFDEQRNYLMIDANQPLNFEAAFEYVSKMRASIVVMGPLLARLGHARVAMPGGCAIGSRPVDLHLKGFEALGATITQSHGYIEAKADQLVGANIYLDFPSVGATQNIMMAATLAKGTTVIENVAREPEIVDLANVLNKMGAKVFGAGTEEIRIEGVTELKGTEHSIVQDRIEAGTFMIAAAATKGNVLVEEAISEHNKPLLSKLAEMGAQVIEEENGIRIIGPDELKPSNIKTLPYPGFPTDMQAQMTALQLMAHGTSVMTETVFENRFMHLEELRRMNADYQIEGQSVILYGPPELTGAEVAASDLRAAAALVIAGLVANGETLVTNLQYMDRGYYHFHQKLRALGAHISRADFDEAGHRKTTQKLA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNB2_ORYJA
Sequence: MSSVEAVTQQQLLAAENPVRMGKGAADPRRAALGEITNRNAAAAANRKMGPSKKQPKPSCAQKPQPVVHTSAGDPAPISADMSMKVEQDLSQAFSEVLMLAVQDVDEQDADQPQLCSQYVKDIYKYLHTLEEQQAIRPNYMQGYSVTEHMRALLVDWLVQVHSRFQLLQETLYLTVAILDRFLQVHPVSRRKLQLVGVTAMLVACKYEEMYPPEVGDFAYITDDAFTKFQIVEMEQVILRSLGFQLGRPLPLHFLRRASKVADADVEKHTLAKYLLELTLLDYHMVHYRPSEAAAAALCLSQLLLDGLPWSLEQQHYSTYDEQHLKPIMQLMAKNVVQVTEGRTKFLAVKKKYSSSKLMKISLIPQLNSSTIKVMAEALQNP
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-B2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: L2GL2_HUMAN
Sequence: MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNGGAE
What is the function of this protein?
Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division.  This complex plays roles in the initial phase of the establishment of epithelial cell polarity.
What are the official names of this protein?
LLGL scribble cell polarity complex component 2, HGL, Lethal(2) giant larvae protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat L(2)GL family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell- cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells.
Protein: TDH_ECO55
Sequence: MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGF11_CANGA
Sequence: MTEQHETIQSVTDGIYNNLVTSMIHSIVSKETAREKLLRSRYGSYKQYHYDPNSQLDIHGNPKQQDSSQYFYCENCGREVSGNRFAAHLQRCLTRGSRR
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  Involved in transcriptional regulation of a subset of SAGA-regulated genes.  Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
What are the official names of this protein?
SAGA-associated factor 11.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NHAB_PSECL
Sequence: MDGFHDLGGFQGFGKVPHTINSLSYKQVFKQDWEHLAYSLMFVGVDQLKKFSVDEVRHAVERLDVRQHVGTQYYERYIIATATLLVETGVITQAELDQALGSHFKLANPAHATGRPAITGRPPFEVGDRVVVRDEYVAGHIRMPAYVRGKEGVVLHRTSEQWPFPDAIGHGDLSAAHQPTYHVEFRVKDLWGDAADDGYVVVDLFESYLDKAPGAQAVNA
What is the function of this protein?
NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.
What are the official names of this protein?
Nitrile hydratase subunit beta, NHase, Nitrilase.
What is the protein family that this protein belongs to?
Belongs to the nitrile hydratase subunit beta family.
Protein: DCYD_ECO55
Sequence: MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTPMAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGGSNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGVTVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLARLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: RL36_CELJU
Sequence: MKVRASVKKICRNCKMVRRNGVLRVICSVEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: KITH_THEP3
Sequence: MIYGSLDHGFIEVIVGPMFSGKSEELIRRIKRAQIAKQKVQVFKPAIDDRYSIDKVVSHNGTNINAISVVKAFEIIELLEEDTEVIAIDEIQFFDHSIVDVVREIADLGKRVICAGLDMDFRGEPFGPTPDVMAIAESVDKLTAICVKCGNPATRTQRLINGKPAKYDDPIILVGAHETYEARCRKCHEVPRT
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1171_LIGS1
Sequence: MFMSALQLVIVTGMSGAGKTVAVQSFEDLGYFCVDNMPPKLLPKFYELVKESGKITKIALVVDLRSRAFYDEIVEMVRELDENEFNSSRILFLDASDEELVARYKETRRSHPLAMEGRILDGIHLERELLAPIKSNAQIIIDTSKLSPRQLREEIFKNFEARDTKTFHIEVMSFGFKYGLPIDADIVMDVRFLPNPYYVSELRNKTGKDDAVYEYVMKSEKTEEFYQKFVSLLKYVIPGYIAEGKSNVTIAIGCTGGQHRSVALAERIGNELSKEYPVHMSHRDMNKRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein LSL_1171.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: LC1L1_HUMAN
Sequence: MKPLLLAISLSLIAALQAHHLLASDEEIQDVSGTWYLKAMTVDRELPEMNLESVTPMTLTILEGGNLEAKATMLISGQCQEVKVILEKTDEPGKYTANRGKHVAYIIRSHMKDHYIFYCEGRDPENNLEALEDFEKAAGARGLSTESILIPRQSETCSPGSD
What is the function of this protein?
May bind a variety of ligands including lipids.
What are the official names of this protein?
Putative lipocalin 1-like protein 1, Lipocalin 1-like pseudogene 1.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERPA_CUPTR
Sequence: MNAVAEAPVTEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFDEEVNEDDTTMVKNGVTLLIDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: IACP_SALTS
Sequence: MNMDIEARVKKVITSCIAVDVDSINGQTHLVEDLYADSLDLIDIVFGLSEEFDISCNENDLPDMMTFADICRVVKKSLESRV
What is the function of this protein?
Acyl carrier protein.
What are the official names of this protein?
Probable acyl carrier protein IacP, ACP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_PARXL
Sequence: MARIAGVNIPNHQHTEIGLTAIYGIGRTRSRDICVAAGVAFSKKVKDLNDADLEKLREEVGKFIVEGDLRRETTMNIKRLMDLGCYRGVRHRKGLPLRGQRTRTNARTRKGPRRAAQSLKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NDUAB_PONPY
Sequence: MAPKVFRQYWDIPDGTDCHRKAYSTTSIASVAGLTAAAYRVTLNPPGTFLEGVAKVGQYTFTAAAVGAVFGLTTCISAHVREKPDDPLNYFLGGCAGGLTLGARTHNYGIGAAACVYFGIAASLVKMGQLEGWEVFAKPKV
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11, Complex I-B14.7, CI-B14.7, NADH-ubiquinone oxidoreductase subunit B14.7.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA11 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Protein: FTSIH_NEPOL
Sequence: MIYNYPMKYRRQFRRLPKHLQGIYYAFLSISTMIKIALDPYSKRPMKWMHSGTPFQYENERMVMIKLSLATVGLLFATRLSGLQFNKYTELKSVAERQQIGQVNDPQQRKIILDHHGDIVAIDLPAYDLYVHPRMCSISLERIAELLSPILDLSSQYLYNRLDEGDSGICLMHQIDTNTSAQIRRLGVDGIELVHHPQRVYPKRGSFESILGYVDTEGYGQAGLESSLDDWMKSTYQDVPCWMDGHGNFLGIRFPKQILFHQESALQLTIDCGLQEKVSQLITNAMNRFGAKRIAAIIMEAHSGAIRCLATSPSYDPNCYGWFPMERFRCWPITDLFEPGSTFKPVNLAIALENGIFQPTDRILDTGKIRIGDSWIGNVGGGFIWDRSLDHLTGTQILQRSSNVGMVRVMQSLDPAIYHRNLIRLGLGSHRNDNQTSFKMSSHDHNESGWNLKDLTSDYAISVVKDQDEFVDHEIEAATASFGQGLAMTPLKLLQLIATIANGGMAVTPHLISKIVTLDHFHHLQSMNEFSLQGWVGQSVLSRSQYHAKQPRPYTHDLYLGHVPVPSLELGWFDVKSIPPHTRERRRLFSRQTCNVLLGMLEQVVLDAQATGSRGFLPGYAMAGKTGTAQKASALGGYSTDSVVTSFVGIYPAVKPKFVTLVIIDEPEDPFRFGFNTAVDVTQTLISEMIVQEQDPPSYPTVSLFERNM
What are the official names of this protein?
Peptidoglycan D,D-transpeptidase FtsI homolog.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Single-pass membrane protein.
Protein: RNP4_METJA
Sequence: MKKFLEKKLKKIAYERIDILMSLAEEEAKKGNWDRAKRYVYLARRIAMKMRIRFPKKWKRRICKKCGTFLLYGRNARVRIKSKRYPHVVITCLECGAIYRIPMIREKKEKRRKKLEERLKAKSNSQTS
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_PEA
Sequence: MALRMWASSTANALKLSSSSRLHLSPTFSISRCFSNVLDGLKYAPSHEWVKHEGSVATIGITDHAQDHLGEVVFVELPEPGVSVTKGKGFGAVESVKATSDVNSPISGEVIEVNTGLTGKPGLINSSPYEDGWMIKIKPTSPDELESLLGAKEYTKFCEEEDAAH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: STXB6_MOUSE
Sequence: MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSVTNKKPTQASITKVKQFEGSTSFVRRSQWMLEQLRQVNGIDPNRDSAEFDLLFENAFDQWVASTASEKCTFFQILHHTCQRYLTDRKPEFINCQSKIMGGNSILHSAADSVTSAVQKASQALNERGERLGRAEEKTEDMKNSAQQFAETAHKLAMKHKC
What is the function of this protein?
Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis.
What are the official names of this protein?
Syntaxin-binding protein 6.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: MUTS_VIBA3
Sequence: MKADQKHTPMMQQYLKLKAENPEILLFYRMGDFYELFYDDAKKASQLLDISLTKRGSSNGEPIPMAGVPYHAVEGYLAKLVQLGESVAICEQIGNPATSKGPVERAVVRIVTPGTVTDEALLSERIDNLIASIYHHNGKFGYATLDITSGRFQLCEPETEEAMAAELQRTSPRELLFPEDFEPVNLMASRNGNRRRPVWEFELDTAKQQLNKQFGTRDLVGFGVEGAKLGLCAAGCLIQYVKDTQRTALPHIRSLTMDKQDHSVILDAATRRNLEITQNLGGGTDNTLAEVLDHTATAMGSRMLKRWLHQPMRNISALDQRLDAIGEMKDLALFTELQPTLKQIGDIERILARLALRSARPRDMARLRQAMEYLPELAETLTQLKHPYLTQLAQYASPVDEVSELLERAIKENPPVVIRDGGVIAEGYNAELDEWRDLAAGATEFLDKLEQEERERHGIDTLKVGYNNVHGFFIQVSRGQSHLVPPHYVRRQTLKNAERYIIPELKEHEDKVLSSKSKALAIEKKLWDELFDLLLPYLERLQNIASSVSQLDVLQNLAERADTLDYCRPTMTESAGVQIQAGRHPVVEQVMDEPFIANPIDLNDQRKMLIITGPNMGGKSTYMRQTALIALMAHIGCYVPAESATIGSIDRIFTRIGASDDLASGRSTFMVEMTETANILHNATPNSLVLMDEIGRGTSTYDGLSLAWASAEWLANQINAMTLFATHYFELTELPNQIPTLANVHLDAVEHGDSIAFMHAVQEGAASKSYGLAVAGLAGVPKAVIKNARAKLTQLEALSIDSPTSKPSGVDIANQLSLIPEPSEVEQALANVDPDDLTPRQALEELYRLKKLL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: UVRB_KLEP3
Sequence: MSKSFVLHSAFRPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMLIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDVFPAESDDIALRIELFDEEVERLSLFDPLTGHVESTVPRYTIYPKTHYVTPRERIVQAMEEIKLELAERRKVLLANNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVIDESHVTVPQIGGMYRGDRARKETLVEYGFRLPSALDNRPMKFEEFEALAPQTIYVSATPGAYELDKSGGEVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRLRTAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNINGKAILYGDKITPSMAKAIGETERRREKQQRYNEEHGIVPQGLNKKVVDILQLGQGLAKTKAKGRGKAKAVEPAGLSAVEMTPKALQQKIHELEGQMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BKRF4_EBVA8
Sequence: MAMFLKSRGVRSCRDRRLLSDEEEETSQSSSYTLGSQASQSIQEEDVSDTDESDYSDEDEEIDLEEEYPSDEDPSEGSDSDPSWHPSDSDESDYSESDEDEATPGSQASRSSRVSPSTQQSSGLTPTPSFSRPRTRAPPRPPAPAPVRGRASAPPRPPAPVQQSTKDKGPHRPTRPVLRGPAPRRPPPPSSPNTYNKHMMETTPPIKGNNNYNWPWL
What is the function of this protein?
Histone-binding protein that binds to histones H2A/H2B, H3/H4 and cellular chromatin to overcome the host DNA damage response triggered by the viral genome ends.  Interferes with histone ubiquitination and recruitment of repair proteins.
What are the official names of this protein?
Tegument protein BKRF4.
What is the protein family that this protein belongs to?
Belongs to the lymphocryptovirus BKRF4 family.
What are the subcellular locations of this protein?
Virion tegument.
Protein: PG121_VACCC
Sequence: MGITMDEEVIFETPRELISIKRIKDIPRSKDTHVFAACITSDGYPLIGARRTSFAFQAILSQQNSDSIFRVSTKLLRFMYYNELREIFRRLRKGSINNIDPHFEELILLGGKLDKKESIKDCLRRELKEESDERITVKEFGNVILKLTTRDKLFNKVYISYCMACFINQSLEDLSHTSIYNVEIRKIKSLNDCINDDKYEYLSYIYNMLVNSK
What is the function of this protein?
Decapping enzyme that remove the protective 5'-cap from both host and viral mRNAs to commit transcripts for decay by the cellular exonuclease XRN1.  Accelerates viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins.  Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis.
What are the official names of this protein?
mRNA-decapping protein OPG121.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: DNAK_CAMC5
Sequence: MAKVIGIDLGTTNSCVSVYERGESKVIPNKEGKNTTPSVVAFTDKGEVLVGDVAKRQAVTNPEKTIYSIKRIMGLMSNEKNAQEAKARLPYHVVDRNGACAVEIAGKVYTPQEISAKILMKLKEDAEAYLGEKVVDAVITVPAYFNDSQRKATKEAGTIAGLNVLRIINEPTAAALAYGLDKKEAEKILVYDLGGGTFDVTVLETGDSVVEVLATGGNAFLGGDDFDNLIIDWLVNEFKNETGIDLKKDVMASQRLKEAAENAKKELSSAQETEINLPFITADATGPKHLVKKLTRAKFEGMIESLVAETITKINEVVKEAGLSKSDVKEVVMVGGSTRVPLVQEEVKKAFGKELNKSVNPDEVVAIGAAIQGAVIKGDVKDVLLLDVTPLSLGIETLGGVMTKIIEKGTTIPVKKNQTFSTAEDNQSAVTIHVLQGEREFARDNKSLGQFNLEGIPSAPRGVPQIEVEFDIDANGILTVSAKDKATGKAQNITISGSSGLSEDEINNMVKDAELHKEDDKKRKEAVEARNSADALVHQTEKSMNELGEKVPAEDRSNIEAALNDLKETLKDENASKEQIDAKVQALSAASHKLAEAMYKKDDNASGEQSGGKKKDDDVIDAEVE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.