PharMolix/UniProtQA huggingface dataset:
Protein: RR11_CENAM
Sequence: MTKTIPKIGSRKKVRIGLRRNARFSLRKSARRITKGVIHVQASFNNTIITVTDPQGRVVFWSSAGTCGFKSSRKASPYAGQRTAVDAIRTVGLQRAEVMVKGAGSGRDAALRAIAKSGVRLSCIRDVTPMPHNGCRPPKKRRL
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUOK2_RHIME
Sequence: MVPLWWSILLGVALFVIGAGGVLLRRNILIVLMSLELLLNSVNINFIAFGQYYDDFRGQIFAIFVIAITAAEVAVALGILVALVRNKSTLKVDDVTIMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 2, NADH dehydrogenase I subunit K 2, NDH-1 subunit K 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VP2_BRD
Sequence: MANPQNRVQTERQQNNSSPYLRGDEVHDDPGIALSVFALQEIIRKVRESQTSLRNEGREVNPAPPEIEQIFSALRHLRDERPYRIERTLPTYYRFESSQSQERFFRVDSHFERIAAPVDNATLEEPARLMSLVSRRVDAIRDAGSFLLYNAPTHFVDGREIIDADGLGVDVSGPASPRRAEGASPATRQIDQLTVLNQDQEDTMVDTYPGACPDAVFRVHRALTAHVVHHQRDDYRNAMQWLQAYGEYKRIDFSRSLLTDVFSPDTVYIQSYHVPANPQLLWEVPRCGIPNLRAKRVLGVPHGTYITPNPRITSITIASRVTTTTSFAQLLGTIPTAAQMDDVRKIYLALMFPNQILLDIRSEPGHQVDVVAQSVAGVLGKLLFSYGPALFNITPHTPGPLIVHAPLSCKWQPMIRRTIRHGPSGRPLDFVITQGQRAFDCNQLAQNPARGNGYAGWGVDAVGDHPTPYPHVRRRIQYLGYVPEDVIDERFCGDDLRYPLHQTMCEALAISGHVNERNYVEMMRHDHVVRFAHLSQVINRDLVSALSLPDERFNMLAAVFPRDATGPDGPLVLDISYMAIIHAFRLRFLPVSRPERIIYQPMLESVYASHLSLAKLHANNLQTFVTANSESFVEARPLDTWRAVYPRLPEPVRQIFDLTGQHSFVTGSDIGLWLRSPLVQDSLFLLCARTAWQAVDDPADIGFTRDVYIHRQPIPGYPLEDVRQFRRDAVYFTNMLEARPANGNRVILDRAIMQQRAGAGRLRMSIRELLDDGLFVQIGIALRPNYFEHPSRLPPEETLRALPFEYRARARNGPTARVTLQMLRPVSAFFMLYNADEQAFPDEMIDLVPKMSLVSLYIQQPPVERVSYDTALSVINRDFVSFRSRVRLMDLSAAFDAGSQYALPSNAM
What are the official names of this protein?
Structural core protein VP2.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP3 family.
What are the subcellular locations of this protein?
Virion.
Protein: BDSF_ANEVI
Sequence: MNKALFLSLVVLCAAVVFAAEDLQKAKHAPFKLAAPCFCSGKPGRGDLWIFRGTCPGGYGYTSNCYKWPNICCYPH
What is the function of this protein?
Blocks Kv3 voltage-gated potassium channels (By similarity).  Reduces blood pressure (By similarity).
What are the official names of this protein?
Kappa-actitoxin-Avd4o, Kappa-AITX-Avd4o, Blood depressing substance 15, BDS-15.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: Y787_HAEIN
Sequence: MKYILIHDLPYQEEEIGITEFYDENDLDTEADIYDRETFGILLGEYVTGLYLLDDTFIEPVLDNINIPNNVYSTNIFAIHYVAKHILGIKDLDKRLKSGDIELVRELGEVTIGGKEKYFYSFATKYCSHHNPIAFPIYDSYVEQVLLYFNKVDKFSAFKRKDLKNYRKFKEVLIDFQRFNLKELDLYLWLLGKEIFPKSKN
What are the official names of this protein?
Uncharacterized protein HI_0787.
Protein: 5NT3_CAEEL
Sequence: MSNKVARRLGKCLFVSGRRFESRQSILQLRTETLTDTPLSATLDQSQFSMFKAAEIVNAAAACAEAECIEQLKKTDVVPLLMNYLLGEEQILVADPTAVAAKLRKMVVGGAGKTVVISDFDYTLSRFANEQGERLSTTHGVFDDNVMRLKPELGQKFVDLKNKYYPIEFSPNLTMEEKIPHMEKWWGTSHSLIVNEKFSKNTIEDFVRQSRIVFKDGAEDFIEALDAHNIPLVIFSAGIGNIIEYFLQQKLGAIPRNTHFISNMILFDEDDNACAFSEPLIHTFCKNSSVIQKETSFFHDIAGRVNVILLGDSMGDIHMDVGVERDGPTLKVGYYNGSLDDTAALQHYEEVYDIVLIHDPTLNVAQKIVDIINSSH
What are the official names of this protein?
Putative cytosolic 5'-nucleotidase 3, Putative pyrimidine 5'-nucleotidase.
What is the protein family that this protein belongs to?
Belongs to the pyrimidine 5'-nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AL1A1_MACFA
Sequence: MSSSGTSDLPVLPTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGATQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTNDIDKAVTISSALQAGTVWVNCYGVVTAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS
What is the function of this protein?
Cytosolic dehydrogenase that catalyzes the irreversible oxidation of a wide range of aldehydes to their corresponding carboxylic acid (PubMed:12576512).  Functions downstream of retinol dehydrogenases and catalyzes the oxidation of retinaldehyde into retinoic acid, the second step in the oxidation of retinol/vitamin A into retinoic acid (PubMed:12576512).  This pathway is crucial to control the levels of retinol and retinoic acid, two important molecules which excess can be teratogenic and cytotoxic (Probable).  Also oxidizes aldehydes resulting from lipid peroxidation like (E)-4-hydroxynon-2-enal/HNE, malonaldehyde and hexanal that form protein adducts and are highly cytotoxic.  By participating for instance to the clearance of (E)-4-hydroxynon-2-enal/HNE in the lens epithelium prevents the formation of HNE-protein adducts and lens opacification.  Functions also downstream of fructosamine-3-kinase in the fructosamine degradation pathway by catalyzing the oxidation of 3-deoxyglucosone, the carbohydrate product of fructosamine 3-phosphate decomposition, which is itself a potent glycating agent that may react with lysine and arginine side-chains of proteins (By similarity).  Has also an aminobutyraldehyde dehydrogenase activity and is probably part of an alternative pathway for the biosynthesis of GABA/4-aminobutanoate in midbrain, thereby playing a role in GABAergic synaptic transmission (By similarity).
What are the official names of this protein?
Aldehyde dehydrogenase 1A1, 3-deoxyglucosone dehydrogenase, ALDH-E1, ALHDII, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, Retinal dehydrogenase 1, RALDH 1, RalDH1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell projection, axon.
Protein: COMD3_HUMAN
Sequence: MELSESVQKGFQMLADPRSFDSNAFTLLLRAAFQSLLDAQADEAVLDHPDLKHIDPVVLKHCHAAAATYILEAGKHRADKSTLSTYLEDCKFDRERIELFCTEYQNNKNSLEILLGSIGRSLPHITDVSWRLEYQIKTNQLHRMYRPAYLVTLSVQNTDSPSYPEISFSCSMEQLQDLVGKLKDASKSLERATQL
What is the function of this protein?
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).  May down-regulate activation of NF-kappa-B (PubMed:15799966).  Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203).
What are the official names of this protein?
COMM domain-containing protein 3, Protein Bup, Protein PIL.
Protein: PSBJ_LACSA
Sequence: MADTTGRIPLWIIGTVAGILVIGLVGVFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: QUEFL_PYRCJ
Sequence: MLKVSKSPSLVRLKTRGESVCPISKTVDSFEVSVEYIPRGAVLAIEEFKKMVDSYRGREILHEELAVDLLEKVKAAVNPPYVKVTVKSYYIGVEVEVVAESGGVPPVYI
What is the function of this protein?
Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA (PubMed:28383498, PubMed:22032275).  Catalyzes the conversion of 7-cyano-7-deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group.  Can use neither glutamine nor asparagine as amino donor in vitro, is only able to utilize free ammonium (PubMed:28383498).  However, the enzyme might function in vivo with a partner that serves to generate ammonium.
What are the official names of this protein?
Archaeosine synthase, Ammonium:preQ0-tRNA aminotransferase, QueF-like amidinotransferase, QueF-L.
What is the protein family that this protein belongs to?
Belongs to the archaeosine synthase type 2 family.
Protein: RSMG_BORA1
Sequence: MSTMPEDIAAAQRLEQACQSLGLAAGAEQQEKLLRYMAQMQRWNRTYNLTAIRDPEQMLIQHLFDSLSVVQPLVRALQAGQPAKVYDVGSGGGLPGVVLAIVQPEWDITCVDAVEKKTAFVQQMAGTLMLPNLHAMHARIERVAPADCDVVISRAFASLHDFANLAGRHVRPGGTLVAMKGKVPAEEIEGLPAAWQVERIEPLQVPELDAERCLIWMRRSQGTL
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_MYCLB
Sequence: MPTIQQLVRKGRRDKIGKVKTAALKGNPQRRGVCTRVYTSTPKKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TNG2_BOVIN
Sequence: MCIIFFKFDPRPVSKNAYRLILAANRDEFYHRPARAADFWGSNNEVLSGLDMEEGKEGGTWLGISTRGKLAALTNYLQPRLNRNARGRGELVAQFLTSDMDSLSYLKKVSAEGHLYNGFNLIAADLSAEKGDVICYYGNRGEREPVVLAPGTYGLSNALLETPWRKLCFGKQLFLEAVERGRELPRDALVAQLLAVLSNDEAQLPDPAIEAQGREYVRPILSKYAAVCVRCPDYGTRTSTVILVDADGHVTFTERSMLGSDPTRWETTTHEFRLQS
What are the official names of this protein?
Transport and Golgi organization protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the Tango2 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Golgi apparatus.
Protein: EGLD_ASPNC
Sequence: MKTTTYSLLALAAASKLASAHTTVQAVWINGEDQGLGNSADGYIRSPPSNSPVTDVTSTDMTCNVNGDQAASKTLSVKAGDVVTFEWHHSDRSDSDDIIASSHKGPVQVYMAPTAKGSNGNNWVKIAEDGYHKSSDEWATDILIANKGKHNITVPDVPAGNYLFRPEIIALHEGNREGGAQFYMECVQFKVTSDGSSELPSGVSIPGVYTATDPGILFDIYNSFDSYPIPGPDVWDGSSSGSSSGSSSAAAAATTSAAVAATTPATQAAVEVSSSAAAVVESTSSAAAATTEAAAPVVSSAAPVQQATSAVTSQAQAPTTFATSSKSSKTACKNKTKSKSKVAASSTEAVVAPAPTSSVVPAVSASASASAGGVAKMYERCGGINHTGPTTCESGSVCKKWNPYYYQCVASQ
What is the function of this protein?
Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan.  Involved in the degradation of complex natural cellulosic substrates (By similarity).
What are the official names of this protein?
Probable endo-beta-1,4-glucanase D, Endoglucanase D, Carboxymethylcellulase D, Cellulase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 61 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1249_SHESR
Sequence: MKKQLLAALIGGFLLAPMAASAADYVIDREGAHASITFKVSHLGYSYVVGRFNDFSGDFSYDAKNPTAAKVNVKVNTLSVDSNHAERDKHIRSGDFLNTAKFAEATFVSTSVEDKGNGDMVITGNFTLNGVTKPLAIQAHAVGEGQDPWGGYRAGFTGTTTFAMKDYGIKMDLGPASANVELDLVVEGVRK
What are the official names of this protein?
UPF0312 protein Shewmr7_1249.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: SEP15_RAT
Sequence: MAAGQGGWLRPALGLRLLLATAFQAVSALGAEFSSEACRELGFSSNLLCSSCDLLGQFNLLPLDPVCRGCCQEEAQFETKKLYAGAILEVCGUKLGRFPQVQAFVRSDKPKLFRGLQIKYVRGSDPVLKLLDDNGNIAEELSILKWNTDSVEEFLSEKLERI
What is the function of this protein?
May be involved in redox reactions associated with the formation of disulfide bonds (PubMed:15659830).  May contribute to the quality control of protein folding in the endoplasmic reticulum (PubMed:11278576).  May regulate protein folding by enhancing the catalytic activity of UGGT1/UGCGL1 and UGGT2/UGCGL2 (By similarity).
What are the official names of this protein?
Selenoprotein F, 15 kDa selenoprotein.
What is the protein family that this protein belongs to?
Belongs to the selenoprotein M/F family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Note=The association with UGGT1/UGCGL1 is essential for its retention in the endoplasmic reticulum.
Protein: NUON_NEIG1
Sequence: MNWSDLNLMPALPEVALLSLLVLLLPADLWASDDKCRWTHYGALATVAVTAAVQLAVWEQGSTSSFNGMYIADGMSRLAKMVLYALTFVLFVYAKPYNQVRGIFKGEFYTLSLFALLGMSVMVSAGHFLTAYIGLELLSLALYALIALRRDSGFAAEAALKYFVLGALASGLLLYGISMVYGATGSLEFAGVLASSFNEEANEWLLKLGLVFIVVAVAFKLGAVPFHMWMPDVYHGAPTSVTALVGTAPKIAAVVFAFRILVTGLGTVHHDWSLMFALLAAASLLVGNLAAIMQTNIKRMLAYSTVSHMGFILLAFMAGAVGFAAGLYYAITYALMAAAGFGVLMVLSDGDNECENISDLAGLNQHRVWLAFLMLLVMFSMAGIPPLMGFYAKFGVIMALLKQGYVWLSVFAVVMSLVGAFYYLRVVKVMYFDESGRARPAAGGNNAAKSLLSVNALLLVLWGIMPQTVIDWCAKALENTL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXD_NEIMA
Sequence: MIPATYTLSQITARLGGEWRGEDTSVTAVRPLADAQAEHISFLANPKYKAEVHDSSAGAVIVSAKAADGFEGRNLIVADDPYLYFAKVARLFSPVVKARGGIHPTAVVEESATVPASCEIGANAYIGANTVLGEGCRILANAVVQHDCRLGDEVVLHPNAVVYYGCTLGRRVEIHSGAVIGADGFGLAFAGDSWFKIPQTGAVTLGDDVEIGSNTNIDRGAMSDTTVGNGTKIDNQVQIGHNCKIGSHTVIAAKTGISGSVTIGSYCIIGGGVGTVGHIEIADKTTIGGGTSVTHSITESGKHLAGIFPMSTHKEWARNAVYIHRLSEMNKRLKTLEQQLSDGKDTQ
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: Y4080_STRGG
Sequence: MGIEEFGGGQAAQADVLVVTTNDVPGYQVTQVIGEVFGLTVRSRHLGSQIGAGLKSMIGGELKGLTKTLVETRNQAMERLVEQARARGANAVLMMRFDVTEAADVGTEVCAYGTAAVISKV
What are the official names of this protein?
UPF0145 protein SGR_4080.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RL36_GEMAT
Sequence: MKVRSSVKPICEHCKVVKRQGVTRIICKRNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DCD_HALMA
Sequence: MILSDADILRRLEQGDLVVEPLDDPDIQIQPASVDLRLGHEFLEFQHANIPCIHPNSEDEVSDYVEETVIEEGGEFILHPGDFVLGTTHERVAIPDDLIAHVEGRSSLGRLAIVVHATAGLCDPGYEGQITLELSNLGTAPVALTPGMRISQLTFTELKTPADRPYGAERGSKYQGQSGPQASKIQGDREFGGDQ
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: FGF7_SHEEP
Sequence: MRKWILTWILPSLLYRSCFHIICLVGTISLACNDMTPEQMATNVNCSSPERHTRSYDYMEGGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEYYLAMNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHSGGEMFVALNSKGVPVRGKKTKKEQKTAHFLPMAIT
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation.  Required for normal branching morphogenesis.  Growth factor active on keratinocytes.  Possible major paracrine effector of normal epithelial cell proliferation (By similarity).
What are the official names of this protein?
Fibroblast growth factor 7, FGF-7, Heparin-binding growth factor 7, HBGF-7, Keratinocyte growth factor.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
Protein: PFKA_STRPC
Sequence: MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_PROM1
Sequence: MDLQNQMKKAVAQAAVDQIQNGMILGLGSGSTAALMIEALAIKIKSGEIKDVVGVTTSFQGEVLASELGIPLKSLSSVSEIDLAIDGADEVDPKFQLIKGGGACHVQEKLVAALAKKFIVVVDSTKLVEKLNLDFKLPVEVLPSAWKQVQKTLINLGGEGNLRMAQKKAGPIVTDQGNLILDLTFRNGIDQPELLETQINNIPGVLENGLFVNLTDEVLVGKVESDVVGVESLKKI
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RNM5_MYCGE
Sequence: MDQKARIKIDGVIVCEGKTDQAKLQQIFDVDVITTNGSALKKETINLIKKISEKQTVILLLDPDQQGKKIRSKLEQHLTNYYNCYVDMNARLKNAKKAGIAEMETSALIAALNNRVAITKNANQSILWDQYLSLKLNDKKKRLLLCNNLNLPYFNHKQLFKKLNLLNLTFQDVWKHLK
What is the function of this protein?
Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor.  Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity).
What are the official names of this protein?
Ribonuclease M5, RNase M5, Ribosomal RNA terminal maturase M5.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease M5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_FLAPJ
Sequence: MAKNIKFDIEARDGLKRGVDALANAVKVTLGPKGRNVIIGKSFGGPTVTKDGVTVAKEIELQDPLENMGAQMVKEVASKTNDLAGDGTTTATVLAQAIVKEGLKNVAAGANPMDLKRGIDKAVEAIVADLTKQAKVVGSDSEKIKQIASISANNDEVIGELIANAFAKVGKEGVITVEEAKGTDTYVDVVEGMQFDRGYLSPYFVTNPEKMDAELENPYILLYDKKVSSLKELLPVLEPVAQSGKPLLIIAEDVDGEALSTLVVNKLRGALKIAAVKAPGFGDRRKAMLEDIAILTGGTVISEERGFTLENTTIEMLGTAKRVTIDKDNTTIVSGAGEADMIKNRVNQIKGQMEASTSDYDKEKLQERLAKLAGGVAVLYVGAASEVEMKEKKDRVDDALHATRAAVEEGIVAGGGVALLRAKNVLKDIKADNADEATGIQIVSRAVEAPLRTIVENAGLEGSVVVAKVAEGSGDFGYNAKTDEYVDMLKAGIIDPKKVTRVALENAASVAGMILTTECALVEIKEENAGGGQMGGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_ALKCK
Sequence: MRQSTYLAPTMRDVPADAEAISHQLMLRAGMMRQIAAGVYAYLPLAKRTIAKIEAIIREELDAIGAQELTLPSLHPAELWQASGRWEAMGDELVRLKDRHNRDFALGPTHEEVITSLIKDGIASYKKLPLCVYQVQTKFRDERRPRFGLLRGREFIMKDAYSFHDSPESLDEAYWQMHGAYSRIFTRVGLEFRPVIADSGAMGGKDTHEFMALASVGEDTVVYSDGSDYAANLEMAKAALPEAPSVQAHGLLEKRATPEAKTVDEAAEALGFDADDIFKALVVVVDDVLSLFILRGNDELNEVKALHELGAKTLRMASEEEVVAAFGATPGSIGPVGVKDVPIYADYRIRSMERIACGANETGYHYVNVGPGRDYEVTAYKDLRTVREGDPSPDGKGTLRFAEGIEIGQIFKLGTRYSESLDAKYLDGQGKAQPFLMGCYGIGVSRTLAAVIEQHHDEAGIVWPKAVAPFDVHLLALNVKNEDQKTLAEQLYSDIRQAGIDVLYDDRPERAGVKFKDADLIGLPVRVAVGKRAGEGIIEVKVRKTGEQLELTASELVRWLNDFLRE
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_PASMU
Sequence: MSISYFMKKIVILGSTGSIGTSTLSVITHNPDKYQVFALVGGRNVELMFQQCLTFQPSFAALDDDVAAKMLAEKLKAHQSQTTVLAGQQAICELAAHPEADMVMAAIVGAAGLLPTLSAVKAGKRVLLANKEALVTCGQLFIDAVRESQAQLLPVDSEHNAIFQSLPPEAQRQIGFCPLSELGISKIVLTGSGGPFRYTPLEQFEQITPAQAVAHPNWSMGKKISVDSATMMNKGLEYIEARWLFNASAEEMEVIIHPQSIIHSMVRYIDGSVIAQMGNPDMRTPIAETMAYPSRTVAGVEPLDFYQLNGLTFIEPDYQRYPCLKLAIDAFSAGQYATTAMNAANEIAVASFLDNKIKFTDIARLNQLVVSKLQPQKIHCIEDVLEVDKKARELSQSIILSFSHP
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.