PharMolix/UniProtQA huggingface dataset:
Protein: PIGD_SERMA
Sequence: MRAATAACRDRRGLCRAEFARLAEAVTPFWLHKELIMTTLTGQARLTNSAAYEQVWQAERQACRTDADPDTLTVGVVVVTRNPAFFQTGLSVLNDIRDYVFNRVHIQSEMPLKLLDLAADSLYLAAREKALHFLKGQNKAINVRIIQCASLAEATGKIIYTHALEQRPEFHLGMLFYDQTTPAGVDDSIEQIDRDLDAFYSALQRSGIPAFYTTFSTVAFIRQLRSPFRYLPQQYREIVRSEDPAIFQTELLCLWMDFFEMNYTNRRVKPIGALALHNTLGEQLIQFFERTAAERWLVSYYTGSIISNLIGYLDRHAEARGALILRGPNEHAIACGAMANWQLYRMPFLGVVTSGMMDEFKGTLANLKETAAQGIIVAAENRGNQWYSFQGTLTPTEDMREVLIARRIPFVYIDDVEMIGAGLTEAFRLYHQGQGPVVILATQNVLESTLSLEGAVCDPSPIPVLSADDPLPMSESLAQAIALINRGPERLVWQLGPVSDDEYALIHDIADAAGIALVDSLAHPGSAPKYYQGRRNPHYLGTLAIYGYSPRVYNFLHTNDKLNAMSEQSLFMIKSRVAQITTPFSDGRLERKVHLVQLTHDDRHLSAYADLHLHMNCLAFLRTVKAHLDVDPALRERRRALIAAYLDSPSDVVSQLPSLPMSANYFFCQLNRVIEELIETEGFDFTGVYDVGRCGISAARNVAKTRRGFSGWYGRALMGDALLATGYLAYTSPSHVMAFIGDGAKGIVPDILPAFIDNILTHPQLLNKSITVFYLCNGGLSVINTYQERILFNRTSRQMRLVNVEQPDVEQTVNNFHIQSKTLTHFDEDVIRQALTTSHRLNLFSVVLGHNNEGDGISPGHRQRLAALIRADHDALQERKAWAAQQPESTSTAFDQDPTQEATS
What is the function of this protein?
Involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (MAP), one of the terminal products involved in the biosynthesis of the red antibiotic prodigiosin (Pig).  Catalyzes the decarboxylation of pyruvate, followed by the modification of the resulting two-carbon fragment acetaldehyde at the C3 position of the 2-octenal (1,2-addition of acetaldehyde) giving 3-acetyloctanal.  In vitro, it can act on a number of alpha,beta-unsaturated carbonyl compounds, including aldehydes and ketones, and can catalyze both 1,2-addition and Stetter-type 1,4-addition depending on the substrate.
What are the official names of this protein?
Thiamine diphosphate dependent-3-acetyloctanal synthase PigD, ThDP-dependent enzyme PigD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: KPRS_BRUME
Sequence: MKLFAGNSNRVLAESVAQYLNIPLGKASVRRFADQEIFVEIQENVRGEDVFVLQSTSYPANDHLMELLIMIDAFRRSSARRITAVLPYFGYARQDRKPGPRTPISAKLVANLITEAGASRVLTLDLHAGQIQGFFDIPTDNLYAVPVIARDVKANYATGNCMVVSPDVGGVVRARSLAKRIDAQLAIVDKRRERPGESEVMNVIGDVSGKDCLLFDDIVDSGGTLCNAAEALLNKGANSVTAYITHGVLSGGAVARIASSKLKELVITDSIQPTTAINDAPNIRVLSISDLIGEAIARTAAEESVSSLFD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_YERPS
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGLSYSRFINGLKKASVEIDRKILADIAVFDKVAFSALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NTPPA_CLOTE
Sequence: MNFILASSSERRKELLKRIVENFEVIPSDYDEKEVAFNGNCSEYVMELSKGKALNVASKLKRDSGIIIASDTIVYFNGEVLGKPSSKEHAYEMLKSLSGEVHEVYSGIVIYDLSSKKIKADYSCSKVKFSNLDDKMIREYIKTGEPMDKAGSYGIQGYGGIFVEKIHGCYYNIVGLPINKLYFLLKEMGVNL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METL_ORYSJ
Sequence: MASGISRTPATGVTAGGGDDEEAAWLHALELISGFTVSMTLKAAIQLGLIDALTAAADGRALTAGELVAQLPAVDDAEAATSVDRMLRLLASFNVVRCSTEAGPGGDPLRRYSPAPVCRWFTAGDNHQGSLAPRLMLDVDEDNLSTWHQMAAAVVSGGPSAFERAHGMPLFEYMGTNHRFNMLFNQAMSQQSMMVMNKLLDRFHGFDGISVLVDVGGGTGVTLKMIISRYKHITGVNFDLPHVISQAPSLPGVNHVAGNMFESVPKGDAIFLKSMLLRNDEECIKILKNCHYALSDNGKVIVVDIVLPETPKPVPEAQNPLRMDVMMLNNLRGGKIRTEQEYAKLAMDSGFSGSFRTTYIFANFMAIELCK
What are the official names of this protein?
Probable inactive methyltransferase Os04g0175900.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: RS19_EXIS2
Sequence: MGRSLKKGPFADHHLLAKVDKANEAGDKHVIKTWSRRSTIFPEFIGHTIAVYDGRKHVPVYVTEDMVGHKLGEFAPTRSYKGHAGNDKKTKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NEGR1_RAT
Sequence: MVLLAQGACCSNQWLAAVLLSLCSCLPAGQSVDFPWAAVDNMLVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTINEGTNVTLTCLATGKPEPAISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITGSACDLFSCWSLALTLSSVISIFYLKNAILQ
What is the function of this protein?
May be involved in cell-adhesion.  May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity).
What are the official names of this protein?
Neuronal growth regulator 1, Kindred of IgLON, Kilon.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IgLON family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: RIOX1_BOVIN
Sequence: MDGLRASAGLLRRGRLRRRRQQQPHSGSVLALPLRPRKIRRQLRRSVSSRMAALRAQTLQSEDSEDSRVESTVGEPGDPLAGGTAALSDATGREPHGQLGPVELLEASPASRSLQTPRALVEAQTPAARLVEAQTPAARLVEAHTPAARLVEAHTPPARLVEASALPARLVETSALLCSTQHLAAVPPSVAPAMLSGPQGESTGEELPWDSPLQRILAELNRIPSSRRRAARLFEWLISPMPPDHFYRRLWEREAVLVRRQDHSYYQGLFSTAVLDSILRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYRAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRVPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTFQRNTWGDFLEAVLPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLRSYPEFVRVGDLPCDTVEDQLSLATMLYDKGLLLTKMPLT
What is the function of this protein?
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase (By similarity).  Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code.  Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2).  Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation.  Also catalyzes demethylation of non-histone proteins, such as CGAS: demethylation of monomethylated CGAS promotes interaction between CGAS and PARP1, followed by PARP1 inactivation (By similarity).  Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216', thereby playing a role in ribosome biogenesis.  Participates in MYC-induced transcriptional activation (By similarity).
What are the official names of this protein?
Ribosomal oxygenase 1, Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, Histone lysine demethylase NO66.
What is the protein family that this protein belongs to?
Belongs to the ROX family. NO66 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: GPMA2_LATSS
Sequence: MAKLVFIRHGQSEWNLSNQFTGWVDVNLSEEGVRQAQNAGALLKKEGILFDQAYTSVLTRAIKTLHYALEGSDQLWIPETKSWRLNERHYGALQGQNKAEAAEKWGDEQVHIWRRSYDTLPPLLDASDEGSAANDRRYAHLDPKAIPGGENLKVTLERVIPFWEDEIAPKLIDGQNIIVAAHGNSLRALTKYIENISDEDIMDVEMATGEPVVYDLDENLNVVSKKKLN
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2, BPG-dependent PGAM 2, PGAM 2, Phosphoglyceromutase 2, dPGM 2.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: POLN_AHEV
Sequence: MDVSQFAESKGVKTALEAAALAAANTALRNARVVTPYLTQQQTKNLLELFRGAQLRFEPRDNWAHPVQRVVHDALEQYVRRAAGPNCLEVGAHPRSINRHQASHRCFLPPVGRDEQRWQVAPRRGLCNLIRRALLNGVKVAREFCQLGFGACSHQCEVGIALYSLHDMRPADVACAMARHNMRTMYVVLHLPEEAMLPPGSYSNKFYNTVNTADKCIITYADDSCAGYVHKREVLQDWITTTGVSGRHPMLIERVRAIGCHFVLLCTATQPCPMPYTPYPSSNTVYVRNVYGPALGAGLFTPKCCVDATFYPVPRRVWQRLMMFGTTLDDDAFCCSRLLTYLRGISTKVTVGNIVANEGWQPEEQQLTAVAIAAYLTVCHQRWVRTQGIARGVRRLQAEHAQQFWFKVWELFTNTGTVPGYSAGFYRQLATWISGGLTIDFERRVFDKRVKCGCCCVCERRPADPGCLCIDDFPDGANGLVKLKKWPIRAGTKSAVSKWAQVRVRADSTEDLIDLSVPKLLTLKELAAAAIRKQPSAPPSLHILDRRPVGDPRRPVNCAPPAVSAGPVPAPPGNPVIESVQGSGAGGPEVSESQPGLTPTREVTNMPLPPQRGQEEVLAVLPSGARVIVGNLLDVAADWLVNPANRDHQPGGGLCGMFHRRWPHLWPVCGEVQDLPTGPVIFQQGPPKVIHAPGPDYRIKPDPDGLRRVYAVVHQAHGTVASPLISAGIYRAPARESFEAWAATARDGDLLVVQRSMAQHIRDFVLNEGRHRPRELHVDRAMADMVNYGLATEPEPYNELVKGVEVAPMTVKYALIAGVPGSGKSSSVDHRGAVVITPTKTLAREWSARGATAVTPHVAASAAPEGRVIVDEAYAIPPHLLVASLRRARDVVMLGDPHQIPALDFDGRCLTSAVDLGLQPTSWRTVSHRCPWDVCIFLRTDYPTITTTSRVLRSVVFTGETIGQKIVFTQVAKQSNPGSITVHEAQGSTFDQTTIIATLDARGLIASSRAHAIVALTRHRERCSVIDVGGVLVEIGVTDAMFNNIEMQLVRPDAAAPAGVLRAPDDTVDGLLDIPPAHTDVAAVLTAEAIGHAPLELAAINPPGPVLEQGLLYMPARLDGRDEVVKLQLSDTVHCRLAAPTSRLAVINTLVGRYGKATKLPEVEYDLMDTIAQFWHHIGPINPSTLEYAEMCEAMLSKGQDGSLIVHLDLQDADCSRITFFQKDCAKFTLDDPVAHGKVGQGISAWPKTLCALFGPWFRAIEKHLVAGLPPGYYYGDLYTEADLHRSVLCAPAGHLVFENDFSEFDSTQNNVSLDLECELMRRFGMPDWMVALYHLVRSYWLLVAPKEALRGCWKKHSGEPGTLLWNTVWNMTVLHHVYEFDRPSVLCFKGDDSVVVCESVRARPEGVSLVADCGLKMKDKTGPCGAFSNLLIFPGAGVVCDLLRQWGRLTDKNWGPDIQRMQDLEQACKDFVARVVTQGKEMLTIQLVAGYYGVEVGMVEVVWGALKACAAARETLVTNRLPVLNLSKED
What is the function of this protein?
RNA-directed RNA polymerase: Plays an essential role in the virus replication (By similarity).  Binds to the 3'-end of the genomic RNA to initiate viral replication (By similarity).
What are the official names of this protein?
Non-structural polyprotein pORF1.
What is the protein family that this protein belongs to?
Belongs to the hepevirus non-structural polyprotein family.
Protein: MURC_ACICJ
Sequence: MRAMPLSIGTIHFVGIAGIGMSGIAEVLHNLGYSVQGSDLSENANVARLRAAGIPVAIGHDAANLGNAQVVVVSTAVPRDNPEVQAARKRMIPVVRRAEMLGELMRLRWSVAIGGTHGKTTTTSLVAAVLEGAGLDPTVINGGIINAYGTNARLGGGDWMVVEADESDGSFLRLPAVIAVVTNMDPEHLDHWGSAEAMEAGYRQFVSNIPFYGFAVLCIDHPGVQRMIPDLSDHRLITYGLSPQADVRAERIMSDRNGATFEVRLSERVAGRERVLAPMRLPMLGNHNVQNALAAIAIGIEMEVPEVDLRAALASFRGVKRRFTKTGEVAGITVIDDYGHHPVEIAAVLRAARQAGARDVIAVVQPHRYTRLATLFEDFCTCMNDAGKVIVADVYPAGEEPIPGIDRDALVEGLRARGHKSVVSLGSPDHLAEMINAMARAGDYVVCLGAGSITNWAQALPNQLQALIETTRRGAGGMR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_PHEZH
Sequence: MLTRKQHELLMFIHERIKETGVSPSFDEMKEALDLASKSGIHRLITALEERGFLRRLPHRARALEVVRLPQQATAAAPPKGRAPFKPQLVEAGQAMPVAANDTRELPILGKIAAGTPIEAIQQERDRLPVPEAMLGAGEHFVLEIQGDSMINAGILDGDFVVIRRTDSANSGDIVVALVDGEEATLKRLRKKGASIALEAANPAYETRIFGPDRVAVQGRLVGLIRRYH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: LMF2_CHICK
Sequence: MGEPPRRPRELFLAGLAAAYLAAFVSLYLQIPGLYGRDGILPARRVLRLSGKGLWEQLRDVPTLLWLGPQLGLDTEQGMELLCLLGAVASMGALLCAPLRDCLLFAVLRVFYLSLYQVGQVFLYFQWDSLLLEAGFLAVLVAPLRLFKWRSTAWRPHDSVTFWLVRWLLFRLMFASGVVKLTSRCPTWWGLTALTYHYETQCIPTPAAWYAHQLPVWFQKFSVVATYVIEIAVPLLFFMPIRRLRLFAFYCQVLLQILIILTGNYNFFNALTIVLAFSLLDEEHMGRWMGRGKRKHGSSAWPPTLLSFLSTLLELATYALLLYWSVHYFSLEIDWEKGLLESKVAFTYHEFTQWLRAVTLPLVGLGFLSLSWEILSALYRCACVRGFFWKLWATLQWAVFATATVGMFAISLVPFTYIDYESNGKLWPGIHQMFSAVERFQVVNSYGLFRRMTGVGGRPEVVLEGSYDKQSWTEIEFMYKPGNVSAAPAVVAPHQPRLDWQMWFAALAHHSSSPWFASFVHRLLQGKEDVIRLVQVDEDKYPFSTQPPVYLRAQLYKYWFTHSAESGAGAAQWWRRQHVQEFFPTVSVGDPTLDGLLAQHGLKDKLPLKRPVDAFLPWLLSSVRQLSRPFSPHVVLWSLYVVAATTCLLRAMARRPRGGAPPTRHKAPKQPRGDQGEKNGQLRRKEGREAEERGEGRSRGAADGEGPRGTKRRK
What is the function of this protein?
Involved in the maturation of specific proteins in the endoplasmic reticulum.  May be required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway (By similarity).
What are the official names of this protein?
Lipase maturation factor 2.
What is the protein family that this protein belongs to?
Belongs to the lipase maturation factor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MSRA_XANCH
Sequence: MLGIGAFKQRMPRPGEALPGREQALPLHNTHLVNGHPLRGEFTGLAQVQFGLGCFWGAERKFWNVPGVYTTAVGYAGGQTPNATYSEVCSGQTGHTEAVLVVFDEQAVSFAQLLRTFWESHDPTQGMQQGNDVGTQYRSAIYCTTQAQYDAALASRDAYQQQLTASGYGDITTEIRFPAPTFYYAEDDHQQYLAKHPNGYCGLGGTGVSCPIGLDA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: UB2L6_MOUSE
Sequence: MMASKRVAKELESLSKELPPYLRQLSSDDANVLVWHMLLLPDQLPYGLKAFQVRIDFPREYPFKPPTLRFTTKIYHPNVREDGLVCLPLISNENWKPYTKPYQVLEALNVLVSKPNLEEPVRLELADLLTQNPEMFRKKAEEFTLKFGVDRPS
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins.  Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.  Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
What are the official names of this protein?
Ubiquitin/ISG15-conjugating enzyme E2 L6, E2 ubiquitin-conjugating enzyme L6, UbcM8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: KBTBD_HUMAN
Sequence: MARGPQTLVQVWVGGQLFQADRALLVEHCGFFRGLFRSGMRETRAAEVRLGVLSAGGFRATLQVLRGDRPALAAEDELLQAVECAAFLQAPALARFLEHNLTSDNCALLCDAAAAFGLRDVFHSAALFICDGERELAAELALPEARAYVAALRPSSYAAVSTHTPAPGFLEDASRTLCYLDEEEDAWRTLAALPLEASTLLAGVATLGNKLYIVGGVRGASKEVVELGFCYDPDGGTWHEFPSPHQPRYDTALAGFDGRLYAIGGEFQRTPISSVERYDPAAGCWSFVADLPQPAAGVPCAQACGRLFVCLWRPADTTAVVEYAVRTDAWLPVAELRRPQSYGHCMVAHRDSLYVVRNGPSDDFLHCAIDCLNLATGQWTALPGQFVNSKGALFTAVVRGDTVYTVNRMFTLLYAIEGGTWRLLREKAGFPRPGSLQTFLLRLPPGAPGPVTSTTAEL
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein 13.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y648_MYCPN
Sequence: MKSQFKANVLAILLVSLFLINGLVFLSKTLFKLFNFRVTHSLNNYYTFNLLIKAWRSIKNDFSSLNNFVFFIERQVHNFIGLLIEQPSIEEDNQPEVIEETPKLEIVVVIEKEVINSKLSDYFCFFKYRSLFFELR
What are the official names of this protein?
Uncharacterized protein MG441 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYV_HAEIE
Sequence: MTQKFEMADRFNPSAVEQALYQHWEESGYFKPSGNENAPSYCIAIPPPNVTGSLHMGHAFQQTLMDTLIRFNRMEGHNTLWQAGTDHAGIATQMVVERKIGAEEGKTRHDYGREAFINKIWDWKAYSGGTISQQMRRLGNSIDWERERFTMDDGLSNAVKEVFVRLHEEGLIYRGKRLVNWDPKLHTAISDLEVENKESKGSLWHFRYPLANGAKTADGKDYLVVATTRPETMLGDTAVAVHPEDERYQSLIGKTVVLPLANREIPIIADEYVDREFGTGVVKITPAHDFNDYEVGKRHGLPMVNVLTLNADIRDEAEIIGTDGKPLAGYEATIPADYRGLERFAARKKIVADFESLGLLDEIKPHDLKVPYGDRGGVPIEPMLTDQWYVSVKPLADVAIKAVEDCEIQFVPKQYENLYFSWMRDIQDWCISRQLWWGHRIPAWYDTEGNVYVARNETEVRSKYNLDFAVELKQDEDVLDTWFSSGLWTFSTLGWPEQTKELKMFHPTDVLITGFDIIFFWVARMIMFTMHFVKDENGKPQVPFKTVYVTGLIRDEQGQKMSKSKGNVLDPIDMIDGISLDDLLEKRTGNMMQPQLAEKIAKATRKEFADGIAAHGTDALRFTLAALASNGRDINWDMKRLEGYRNFCNKLWNASRFVLTNDKLDLSEGEIEFSLADRWIQSEFNRTVETFRNSLSQYRFDLCANAIYEFTWNQFCDWYLELTKPVFANGNAAQIRAASQTLVHVLEKLLRLAHPLIPFITEEIWQKVKGFVGITADSIMLQPFPQVEESGFDLEAEAEIEWLKEVIVAVRNIRAESNIAPSKGLDLLFRNLSTENAKILEKQTALLKAMAKLDNVQVLAANETAPLAVAKLVGNAELLVPMAGFINKEAELARLTKEIEKYQNEVKRIENKLSNEAFVAKAPEAVIAKEREKQAEYQSGLEKIQEQYKAIEAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_SYNSC
Sequence: MAQLFYDSDADLGLLNGKTVAIIGYGSQGHAHALNLKDSGVNVVVGLYDGSRSAEKAKADGLEVLSVADASAKADWIMVLLPDEFQKDVYEKEIAPHLNAGKVLSFAHGFNIRFELIKPPADVDVVMIAPKGPGHTVRWEYQNGQGVPALFAIEQDASGNARGMAMAYAKGIGGTRAGILETNFKEETETDLFGEQAVLCGGLSELVKAGFETLVEAGYQPELAYFECLHEVKLIVDLMVKGGLTSMRDSISNTAEYGDYVSGPRLITADTKAEMKRVLADIQDGTFARNFVAECEAGKPEMKKVRDRDSQHPIEKVGKGLRSMFSWLKDA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RL3_BLOPB
Sequence: MKGLIGQKLGMTRLFDKDGVSIPVTMIEITPHRVTQIKNIENDGYCAVQVTTGMKNFKHINRPETGHMIKSGVDAGRGVWEFRCEEAGMPQLSLGDIITIQIFKNVKKVDITGISKGKGFAGTIKRWNFHMQDASHGNSLSHRAPGSIGQNQTPGRVFKGKKMAGQLGNYKVTVQNLDVVNVDVKLNLLLVKGAVPGTIGGNLSIKKSVKINIREKM
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: EFTU_THEMA
Sequence: MAKEKFVRTKPHVNVGTIGHIDHGKSTLTAAITKYLSLKGLAQYIPYDQIDKAPEEKARGITINITHVEYETEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVEVPYMIVFINKTDMVDDPELIDLVEMEVRDLLSQYGYPGDEVPVIRGSALKAVEAPNDPNHEAYKPIQELLDAMDNYIPDPQRDVDKPFLMPIEDVFSITGRGTVVTGRIERGRIRPGDEVEIIGLSYEIKKTVVTSVEMFRKELDEGIAGDNVGCLLRGIDKDEVERGQVLAAPGSIKPHKRFKAQIYVLKKEEGGRHTPFTKGYKPQFYIRTADVTGEIVGLPEGVEMVMPGDHVEMEIELIYPVAIEKGQRFAVREGGRTVGAGVVTEVIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEA3_ARATH
Sequence: MAQHQHSPQRPRDQDNTRPHDQYGIVFSVSGDDVARKQGDSFSQPDPTVATMGSVDTVTIGEALEATALSLGDKPVDRRDAAAIQAAETRATGESKGRPGGLAVAAQAAATTNEQTVSEEDKVNIADILTDAAERLPGDKVVTSEDAEAVVGAELRSSSEMKTTPGGVADSMSAGARLNQQL
What is the function of this protein?
LEA proteins are late embryonic proteins abundant in higher plant seed embryos.  The function of those proteins is not known.
What are the official names of this protein?
Late embryogenesis abundant protein 3, LEA 3.
What is the protein family that this protein belongs to?
Belongs to the LEA type SMP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HIS4_CAMJJ
Sequence: MTQIIPALDLIDGEVVRLVKGDYEQKKVYKYNPLEKFKEYEKAGAKELHLVDLTGAKDPSKRQLALIEKLAKEVSVNLQVGGGIRSKEEVKALLDCGVKRVVIGSMAIKNATLCLEILKEFGSEAIVLALDTILKEDYVVAVNAWQEASDKKLMEVLDFYSNKGLKHILCTDISKDGTMQGVNVRLYKLIHEIFPNICIQASGGVASLKDLENLKGICSGVIVGKALLDGVFSIEEGIRCLAN
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCOB_XANCP
Sequence: MAWTRDQMAARAARELTDGAYVNLGIGLPTLVANHIPDGVDVWLQSENGLLGIGPFPGEDEVDADLINAGKQTVTARSGASYFGSHDSFAMIRGGHIDLAILGAMQVTDRGDLANWMVPGKMVKGMGGAMDLVAGVKRVVVLMEHVAKDGTHKILPQCDLPLTGVGVVDRIITDLAVFDVTDGGLVLVEAAEGVGLEELRAKTGVAFVVQTRG
What are the official names of this protein?
Succinyl-CoA:3-ketoacid coenzyme A transferase subunit B, OXCT B, Succinyl-CoA:3-oxoacid CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit B family.
Protein: LEPA_CALBD
Sequence: MERRQDRIRNFCIIAHIDHGKSTLADRIIELTGALTEREMQDQVLDTMDIERERGITIKAQAVRLNYKAKDGKEYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDATQGIEAQTLANVYLALEHNLEIIPVINKIDLPSARPEEVKKEIEDVIGLDASDAPLISAKMGINIEEVLERIVRDIPPPKGDDTKPLKALIFDSLYDNYKGVLAYVRVFDGVVKPNMTIKMMSTGAQFTVTEVGYFKPGMLIPCEELRAGDVGYIAASIKTVRDTRVGDTITDANNPADEPLPGFRRLNPMVFCGIYPTGDTKYEELKEALEKLQLNDAALFFEPESSAALGFGFRCGFLGLLHMEIVQERLEREYDLNIITTAPSVVFKVTKTDGEVLYIDNPTKLPPPNEIAKMEEPMVKATIMVPNEFVGSVMELCQERRGIFKDMSYIETTRVILTYEMPLMEIVYDFFDALKSRSKGYASFDYEFIGYAESKLVKLDIMIKGEVVDALSFIVHKDKAYQRARRIVEKLKEEIPRHLFEIPIQACIGSKVIARETVKALRKDVLAKCYGGDVTRKKKLLEKQKEGKKRMKQVGEVEIPQEAFMAVLKLED
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.