PharMolix/UniProtQA huggingface dataset:
Protein: SLMA_VIBA3
Sequence: MAGTRKSNRREEILQALAQMLESTEGASRITTVKLAKQVGVSEAALYRHFPSKARMFEGLIEFIEEALMSRINRILDEEKDTLERIRLVLQLILVFSERNPGLTRILSGHALMFENERLRDRINQLFERIETQLRQILRERKLREGKSFPVDEKILAAQLLGQVEGSLNRFVRSDFKYQPTENFDAYWALLSAQIK
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: JJJ2_YEAST
Sequence: MSQVIEPQLDRTTYYSILGLTSNATSSEVHKSYLKLARLLHPDKTKSDKSEELFKAVVHAHSILTDEDQKLRYDRDLKIKGLHTYQPKKNCHIFKTKAKESQGASPTLGQSEAYHRQNKPYEQQPYGFGVGKKMTSSSKSKVPIFKSFNLKSYQRNHYYSSKKERKHGSPDIDSLFHETNGASKVRMTDAGKMDTNSQFQEIWEILGKNAYTHKSYSEDPNSCLGSALSDHEEEEEAGKQQQQQQQQQQQQQHYGMTSKSSSPDEEKKNNKEPKRESRVSPEENGEEETGHKQFKLPKTSTFSSGSHDSNLQSPFYNHEYRHYARSKFECKNQFRKSVSPIKEIPATTSANEGWNILRDIIEKLNISNVDDRNKDLLFRRDEIGDKNHSDSIDIENLSIKEPKGMKRRKKDDISLEELFQSLPREKDYFMMDAINDSLESINLFKKPKTTQSHEQGGTFAQAESNRAKFKPLLEQCGITPEILDLEIPEIPEFDAVADLETLKLNVQLFNNQCNKLKETIHQVSLQRLRADTQFSDMLTQKQSIMVWKTYLEFDKSLMDKLNILQERQMQVIKIFSERCDGKV
What are the official names of this protein?
J protein JJJ2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL31B_PSEFS
Sequence: MKAGIHPDYRTVLFHDTAADVFFLIGSTADSDRTHVHSDGNTYPYIPLDVSSASHPIYTGQQRKTQVEGRIAGFNKRFASFGSGAKKAEE
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: ANFB_CANLF
Sequence: MEPCAALPRALLLLLFLHLSPLGGRPHPLGGRSPASEASEASEASGLWAVQELLGRLKDAVSELQAEQLALEPLHRSHSPAEAPEAGGTPRGVLAPHDSVLQALRRLRSPKMMHKSGCFGRRLDRIGSLSGLGCNVLRKY
What is the function of this protein?
May affect cardio-renal homeostasis.  Able to promote the production of cGMP although its potency is very low compared to brain natriuretic peptide 32.
What are the official names of this protein?
Natriuretic peptides B, Brain natriuretic factor prohormone, preproBNP, proBNP, Gamma-brain natriuretic peptide, Iso-ANP.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Brain natriuretic peptide 32]: Secreted. Note=Detected in blood.
Protein: IF2_PECAS
Sequence: MTDVTVKSLAAEIQTPVDRLVQQFADAGMTKSASDSVTQHEKETLLAHLNRDRGNAPSKLTLQRKTRSTLNVPSTGGKSKSVQIEVRKTRTYVKRDPIEAQQAEEEEQARREAEEQAQRAAEEQVKREADLRETAEKAKRAADEQAKREAAEKAKRDVAEKEKVTNQQNENMTKPAQSEKAKREAEAAELKRKAEETARLKVEEEARRIAEEARRMAEENAGRWEAESATKPEESADYHVTTSHHAREAEDENDRQVEGERRTRTRAAKVTKQKKGNRQSESKADREEARAVTRGGKGKRKPSSLQQSFNKPVQAVNRDVVIGETVTVAELANKMAVKGSQVIKTMMRLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDMGVAAEFRAPVVTIMGHVDHGKTSLLDYIRSTKVAAGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTAMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPDADPDRVKTELSQYGIMPEEWGGESQFVHVSAKAGTGIDELLNAILLQAEVLELKAVRSGMANGVVIESFLDKGRGPVATVLVREGTLNKGDIVLCGFEYGRIRAMRDELGREITSAGPSIPVEILGMSGVPAAGDEATVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVSELNIVLKSDVQGSCEAISDSLQKLSTDEVKVKIVGSGVGGITETDATLAAASNAIILGFNVRADASARRVVEAESLDLRYYSVIYDLIDEVKQAMSGMLAPEYKQEIIGLAEVRDVFKSPKFGAVAGCMVTEGIVKRHNKIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRPGDMIEVFETIEIKRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SAS_NAJSG
Sequence: LKCNKLVPLAYKTCPAGKNLCYKMYMVANKKVPVKRGCIDVCPKKSLLVKYECCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kill the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin sagitoxin, Cardiotoxin sagitoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: UREF_CERS1
Sequence: MSAALLSLVQWLSPAFPTGAFAYSHGLEWAISEGEVRDAASARRWIADVLAFGAGRTDAILLAHALRGHDPEALSDLARALAPAAERLRETEEQGAAFAATVAALTGRDLPPRPLPVALGQAAAPLGLPVAEVLALMLHAFAANLVSAAVRFVPLGQTEGQATLAALHPLIGEIAAESAEAPLDALGSAALRGDLAAMRHETQEVRIFKT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_PSEAE
Sequence: MIIKREMRQDKRAQPKPPINENISAREVRLIGADGQQVGVVSIDEAIRLAEEAKLDLVEISADAVPPVCRIMDYGKHLFEKKKQAAVAKKNQKQAQVKEIKFRPGTEEGDYQVKLRNLVRFLSEGDKAKVSLRFRGREMAHQELGMELLKRVEADLVEYGTVEQHPKLEGRQLMMVIAPKKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_COXBN
Sequence: MPKERYIGLISGTSMDALDTALVQFDPLKIIATHGEPIPTELKKNLVALSTGTDNSIPSMGETDVALGRLFGEAVLTLLEKAKVSSDSIQAIGSHGQTIRHMPNGKHPFTLQIGDPNTIAALTGITTVADFRRRDMALGGQGAPLAPAFHEFLLRDQSENRLILNIGGIANLTFLPRDPEKSTIGFDTGPGNTLLDAWCLMNLNKDYDDQGQWAASGRVQEKLVAQLLAEPYFQTPPPKSTGREYFNLNWLKKNLNGEKFDPVDIQATLVELTARSVANCCRNFSMDSGSLWLCGGGARNHHLVNRLKVLCKPLRVTTTEEIGIHPDWLEAVCFAWLAKQTLEKKPGNLPSVTGAKKSAILGAIYWGEKFNY
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: TRUA_STRPJ
Sequence: MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTITVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHCRYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTASGTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQIDLILEKKDRQLAGPTAAPNGLYLKEIRYEE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RISA_CHLMU
Sequence: MFSGIIQEVARVDLIHHYGDSMEIGIFARNLVDGVPGSSIAVDGICLTLVKREFELLFFDVTEETMACTTIKNYTVGSMVNLERSVRLGDEIGGHFVSGHVCGVGTIIAVEKSYMFFKAPTNLVPYVLEKGFIAIDGISLTIAQVRGDIFSVSVIPETRARTSLGYKQVGSHVNMEPDMMTKMQVDTVMRFQAEKIGK
What is the function of this protein?
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
What are the official names of this protein?
Riboflavin synthase, RS.
Protein: Y042_UREPA
Sequence: MSPISIELIIQISIGLSASLILLFAFLPQTLLTIKTKNTAALTISMFIICFIARLCFSLSAILTIIVYIHNQNYGLSLYALTLPVLICHGINMLLNLIIAFIKINNVYKAKIHKMNENEYIIFAYAQKLKEKVSIKNK
What are the official names of this protein?
Uncharacterized protein UU042.
What is the protein family that this protein belongs to?
To U.parvum UU007, UU008 and UU041.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR4_SHEFN
Sequence: MEIIRGAPALSAFRVQKLMEACENAALPVSQIYAEYVHLASLSEPLDDNERLQLETILTYGPAIESHAPQGTLLFVTPRPGTISPWSSKATDIAHNCGLGKVSRLERGIAYYVEASVLTAEQQKLLQGLLHDRMVEVMLPAFEAAEVLFARTEPAKFSSVNILAEGRRALEVANIKLGLALADDEIDYLIENFVRLKRNPNDIELMMFAQANSEHCRHKIFNADWTIDGEVQLKSLFKMIKNTFEVTPDYVLSAYKDNAAVMTGSVAGRFFPDPDGIYNYHTEPMHILMKVETHNHPTAISPYPGAATGSGGEIRDEGATGRGSKPKAGLSGFTVSNLKIPGFVQPWEGDYGKPDRIVTPLEIMLEGPLGGAAFNNEFGRPAITGYFRTYEQLVSSHNGVEVRGYHKPIMIAGGLGNIREDHVQKGEITIGAKLIVLGGPAMNIGLGGGAASSMASGQSSEDLDFASVQRENPEMERRCQEVIDRCWQLGDTNPIQFIHDVGAGGLSNAFPELVNDADRGGVFNLRNVPSDEPGMSPLEIWCNESQERYVLSVAPENLQQFADICARERAPFAVVGEATAEMHLTLADSHFNNKPIDLPLEVLLGKAPKMSRDVVTAKAVSPALDQTKIELKDAVKRILTLPTVADKTFLITIGDRSVTGLVNRDQMVGPWQVPVADCAVTASSYDSYCGEAMSMGERTPLALLDFDASARMAVAESIMNIAGTDIGSFKRIKLSANWMSPAGHPGEDAGLYQAVKAIGEDLCPELGITIPVGKDSMSMKTAWEDNGTQKTVTSPMSLVITAFGVVQDIRKTVTPQLRSDKGDSALLMLDLSNGQNRLGGSCLAQVYSELGDIAPTLDKTANLAGFFEVMQQLVADQAVMAYHDRSDGGLFTTLVEMAFAGNTGLTIDLASLSGTDLERLFNEEIGAVIQVSAIDAKAIAAQFEAKGVTCHHIGGLQTADKISINDGERVIFADSRTALRTLWSETTYRMQALRDNPECAREEYELKQQADAPGLTVKLGFNPSEDVAAPYILKGVAPKMAILREQGVNSHVEMAAAFDRAGFESRDVHMSDILSGRISLEEFQGLVACGGFSYGDVLGAGEGWAKSILFNDRARDEFSRFFERDSSIALGVCNGCQMLSNLKEIIPGSEHWPRFVRNRSERFEARFSLVEVQQNPSVFFEGMVGSRMPIAVSHGEGLVEFANAQALANAEASGTIALRYVDGHGQIATQYPENPNGSANGLTGICTTDGRVTIMMPHPERVFRTVANSWHPDNWGEDSPWMRMFRNARVKIG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CKX1_ARATH
Sequence: MGLTSSLRFHRQNNKTFLGIFMILVLSCIPGRTNLCSNHSVSTPKELPSSNPSDIRSSLVSLDLEGYISFDDVHNVAKDFGNRYQLPPLAILHPRSVFDISSMMKHIVHLGSTSNLTVAARGHGHSLQGQALAHQGVVIKMESLRSPDIRIYKGKQPYVDVSGGEIWINILRETLKYGLSPKSWTDYLHLTVGGTLSNAGISGQAFKHGPQINNVYQLEIVTGKGEVVTCSEKRNSELFFSVLGGLGQFGIITRARISLEPAPHMVKWIRVLYSDFSAFSRDQEYLISKEKTFDYVEGFVIINRTDLLNNWRSSFSPNDSTQASRFKSDGKTLYCLEVVKYFNPEEASSMDQETGKLLSELNYIPSTLFSSEVPYIEFLDRVHIAERKLRAKGLWEVPHPWLNLLIPKSSIYQFATEVFNNILTSNNNGPILIYPVNQSKWKKHTSLITPNEDIFYLVAFLPSAVPNSSGKNDLEYLLKQNQRVMNFCAAANLNVKQYLPHYETQKEWKSHFGKRWETFAQRKQAYDPLAILAPGQRIFQKTTGKLSPIQLAKSKATGSPQRYHYASILPKPRTV
What is the function of this protein?
Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group (PubMed:11504909, PubMed:14555694).  Catalyzes in vitro the oxidation of various types of cytokinin nucleotides that are known as direct products of cytokinin biosynthesis (PubMed:20825956).  Promotes adventitious root initiation downstream of MYC2-dependent jasmonate signaling (PubMed:34329421).  Cytokinin degraded by CKX1 is required for cell division in the female gametophyte by modulating the expression of cell cycle genes (PubMed:35995110).
What are the official names of this protein?
Cytokinin dehydrogenase 1, Cytokinin oxidase 1, AtCKX1, CKO 1.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Vacuole.
Protein: DNSL1_BOVIN
Sequence: MHSSGGFQKAIHGHALLLLLLLASGAETFRICAFNAQRLTLAKVAREPVLDTLVKILARCDIMVLQEVVDSSDTAIPLLLRELNRFGDSGPYASHSSLLLGRSTYKEKYVYLYRSHEAEVRDSYMYDDQDDLFTREPFVCWFSLRSKVLPSLVLVPLHTTPKAVETELNALYDVFLDASGRWQTKDVILLGDFNADCTSLTKKRLDDLVLRTQAGFHWAIADGVDTTVRASTHCTYDRIVLHGELLQSLLRGAAAFDFPQSFGLTEQEALNISDHYPVEVDLALSWAVHGVQPPCLATLWLSLLLPLLAPQLGLVA
What are the official names of this protein?
Deoxyribonuclease-1-like 1, DNase X, Deoxyribonuclease I-like 1, DNase I-like 1.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: RPO2A_TOBAC
Sequence: DPFQCLAVCINLSEAVRSSSPETSVSHIPVHQDGSCNGLQHYAALGRDKLGAAAVNLVAGEKPADVYSGIAARVLDIMKRDAQRDPAEFPDAVRARVLVNQVDRKLVKQTVMTSVYGVTYIGARDQIKRRLKERGAIADDSELFGAACYAAKVTLTALGEMFEAARSIMTWLGECAKIIASENEPVRWTTPLGLPVVQPYRKIGRHLIKTSLQILTLQRETEKVMVKRQRTAFPPNFIHSLDGSHMMMTAVACRRAGLNFAGVHDSYWTHACDVDKLNRILREKFVELYEAPILEKLLESFQTSYPTLLFPPLPERGDFDMRDVLESPYFFN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase 2A, NictaRpoT2-syl, T7 bacteriophage-type single subunit RNA polymerase 2A.
What is the protein family that this protein belongs to?
Belongs to the phage and mitochondrial RNA polymerase family.
Protein: XCL2_HUMAN
Sequence: MRLLILALLGICSLTAYIVEGVGSEVSHRRTCVSLTTQRLPVSRIKTYTITEGSLRAVIFITKRGLKVCADPQATWVRDVVRSMDRKSNTRNNMIQTKPTGTQQSTNTAVTLTG
What is the function of this protein?
Chemotactic activity for lymphocytes but not for monocytes or neutrophils.
What are the official names of this protein?
Cytokine SCM-1 beta, C motif chemokine 2, XC chemokine ligand 2.
What is the protein family that this protein belongs to?
Belongs to the intercrine gamma family.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEC_METPP
Sequence: MSLDPRGALVLFSGGQDSTACLAWALEHHAHVETIGFDYGQRHVVELECRVQVREAIARSFPLWAGRLANDHVLDLGLLGQISDTALTSARAIEMQANGLPSTFVPGRNLLFLGFAATVAYRRNLSVLVGGMCETDYSGYPDCRDNTLKALQVALSLGMATPMTIETPLMWLDKARTWALTDRLGGRALNELILEHTHSCYLGDRSVRHAWGYGCNACPACELRRKGYEAWCAGA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: CDGT_THETU
Sequence: MKKTFKLILVLMLSLTLVFGLTAPIQAASDTAVSNVVNYSTDVIYQIVTDRFVDGNTSNNPTGDLYDPTHTSLKKYFGGDWQGIINKINDGYLTGMGVTAIWISQPVENIYAVLPDSTFGGSTSYHGYWARDFKRTNPYFGSFTDFQNLINTAHAHNIKVIIDFAPNHTSPASETDPTYAENGRLYDNGTLLGGYTNDTNGYFHHYGGTDFSSYEDGIYRNLFDLADLNQQNSTIDSYLKSAIKVWLDMGIDGIRLDAVKHMPFGWQKNFMDSILSYRPVFTFGEWFLGTNEIDVNNTYFANESGMSLLDFRFSQKVRQVFRDNTDTMYGLDSMIQSTASDYNFINDMVTFIDNHDMDRFYNGGSTRPVEQALAFTLTSRGVPAIYYGTEQYMTGNGDPYNRAMMTSFNTSTTAYNVIKKLAPLRKSNPAIAYGTTQQRWINNDVYIYERKFGNNVALVAINRNLSTSYNITGLYTALPAGTYTDVLGGLLNGNSISVASDGSVTPFTLSAGEVAVWQYVSSSNSPLIGHVGPTMTKAGQTITIDGRGFGTTSGQVLFGSTAGTIVSWDDTEVKVKVPSVTPGKYNISLKTSSGATSNTYNNINILTGNQICVRFVVNNASTVYGENVYLTGNVAELGNWDTSKAIGPMFNQVVYQYPTWYYDVSVPAGTTIQFKFIKKNGNTITWEGGSNHTYTVPSSSTGTVIVNWQQ
What is the function of this protein?
Degrades starch to alpha-, beta-, and gamma-cyclodextrins, as well as linear sugars.
What are the official names of this protein?
Cyclomaltodextrin glucanotransferase, Cyclodextrin-glycosyltransferase, CGTase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACKA_METAC
Sequence: MKVLVINAGSSSLKYQLIDMTNESPLAIGLCERIGIDNSIITQKRSDGKKLEKQTDLPNHKVALEEVVKALTDSELGVIKSMDEINAVGHRVVHGGEKFTSSALIDEGVEQAIKDCFELAPLHNPPNMMGITACQEIMPGVPMVAVFDTAFHQTIPAYAYMYALPYTLYEKYGIRKYGFHGTSHFYVARRAAAMLGKPEEEVKVITCHLGNGSSITAVNGGKSVETTMGFTPLEGVAMGTRCGSIDPAVVPFVMEKEGLTTREIDTLMNKKSGVLGVSGLSNDFRDLDEAASKGNQRAELALEIFAYKIKKVIGEYSAVLNGADAVVFTAGIGENSASIRKRILSGLDGLGIEIDEEKNKIRGQEIDISTPDAKVRVLVIPTNEELTIARDTKEICETEVKLRRSVSI
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_CHRVO
Sequence: MTTEDRVEIYTDGACKGNPGPGGWGALMRYKGKEKELFGGERGTTNNRMEIMAVIRALAALNRPCKVVVYTDSQYVQKGISEWIHGWKARGWKTAAKEPVKNADLWQQLDAERNRHLDVEWRWVKGHAGHEFNERADQLANKGVESV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGR_PYRFU
Sequence: MKYDVVVVGSGVAGPIVARDVAKAGFSVLLVDKKPAIGTPKQCAEGINVNVFKEFDIPYDKRFINREIYGARIYSPSGYTAELRYDKVSGVILERKVFDKMLAYYAAKAGADVWARTEVIDLLRKEGKIMGVKAKHEGELVEIEAKIIVAADGVESTVARLAGINTYAPPHEFDSAYEYEMIIEGYDPDLIHLWFGNEIAPRGYVWVFPKDEDRANVGIGINSDNEKTAKYYLDKWLKENNIPTKKILEINVGLVPVGGFVRELVKENVAVVGDAARQVNPVHGGGMYEAMKAANILAKWIVKALEEENLELLKNYTKEWWEVEGPKMERLLKLRRAMEKLTDEDIDVFVQLLGGTDLEKLAGGNYFEVVKALMKHPKVLMSKRRLEILKALL
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
Protein: LFTR_PSYA2
Sequence: MNNINDSSAIHITPETFVKQIRSLGRYNFPEPALVDPDGIGIVGIGGNLAPETLISAYAQGLFPWFNDDEPIAWWCPEPRCVMQPTDYQPSKSLRKQANNARWQLTLNQAFNEVIHACSLPRSNGLPEGEHTWIHDDMIEAYNELHAQGFAHSVEVWDDQGQLVGGLYGLKIGSIYFGESMFHIASNASKLAFWGLMRLCTQSNVTLVDCQLPNEHLMSLGAITLSRTEFLTQLDTLISNGSDAWHKNSHRPLAVSLLGNLQPWQLNP
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA1_CLOAB
Sequence: MSIFKGSAVALITPFTQDGVNFDELKKLLEWHIKNKTDAIVICGTTGEASTMSLNERKETIKYTVETVNKRIPVIAGTGSNNTKSSVEMSIWAEKIGVDGVLVITPYYNKTTQKGLIEHFKSINDNINIPIILYNVPGRTGLNILPETLYAMRDLKNICAIKEASGNISQIAKIKALCRDRFDIYSGNDDQIVPILSLGGSGVISVLANIIPQTVHDMCFSYFQGKTTDALNLQLDTLSLTNSLFIETNPIPIKTAMNLLNFNAGPLRLPLCSMDEKNLNTLKTDLKGYGLIK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase 1, HTPA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_ROSDO
Sequence: MAKKLVGSMKLQVPAGQANPSPPVGPALGQRGINIMEFCKAFNAKTADMEQGAPCPTVITYYQDKSFTMDIKTPPASYYLKKAAKLSSGAKTPSREVVGYVSSKQVREIAEAKMKDLNATSIEAAMKIILGSARSMGIEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SPNS1_BOVIN
Sequence: MSGSDTAPFLSQADDTDDGPAPGTPGLPGSMGNPKSEDPAVPDQEGLQRITGLSSGHSALIVAVLCYINLLNYMDRFTVAGVLPDIEQFFDIGDGSSGLIQTVFISSYMVLAPVFGYLGDRYNRKYLMCGGIAFWSLVTLGSSFIPRERFWLLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSVFYFAIPVGSGLGYIAGSKVKDVAGDWHWALRVTPGLGVLAVVLLFLVVQEPPRGAVERHSDSPPLNPTSWWADLRALARNPSFILSSLGFTAVAFVTGSLALWAPAFLLRSRVVLGETPPCLPGDSCSSSDSLIFGLITCLTGVLGVGLGVEISRRLRRTNPRADPLVCAAGLLGSAPFLFLALACARGSIVATYIFIFIGETLLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAGSPYLIGSISDRLRRDWPPSFLSEFRALQFSLMLCAFVGALGGAAFLGTAIFIESDRRQAQLHVQGLLPETGPTDDRIVVPQRGRSTRVPVSSVLI
What is the function of this protein?
Plays a critical role in the phospholipid salvage pathway from lysosomes to the cytosol.  Mediates the rate-limiting, proton-dependent, lysosomal efflux of lysophospholipids, which can then be reacylated by acyltransferases in the endoplasmic reticulum to form phospholipids.  Selective for zwitterionic headgroups such as lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), can also transport lysophosphatidylglycerol (LPG), but not other anionic lysophospholipids, sphingosine, nor sphingomyelin.  Transports lysophospholipids with saturated, monounsaturated, and polyunsaturated fatty acids, such as 1-hexadecanoyl-sn-glycero-3-phosphocholine, 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine and 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine, respectively.  Can also transport lysoplasmalogen (LPC with a fatty alcohol) such as 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine.  Essential player in lysosomal homeostasis.  May be involved in necrotic or autophagic cell death.
What are the official names of this protein?
Protein spinster homolog 1, BSpin1, Spns1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLYA_SYNY3
Sequence: MNQTNLDFLATSDPALAAIIDRELQRQRTHIELIASENFTSAAVMAAQGSVLTNKYAEGLPGKRYYGGCEFVDQAETLAISRVKELFGAAHANVQPHSGAQANFAVFLTLLQPGDTIMGMDLSHGGHLTHGSPVNVSGKWFEVAHYGVEKETGRLDYDKIRQQALEVKPKLLICGYSAYPRQIEFDKFRAIADEVGAYLMADIAHIAGLVASGHHPSPLPYCDVVTTTTHKTLRGPRGGLIMTNNEELGKKFDKSVFPGTQGGPLEHVITAKAVAFGEALKPEFKVYSGQVIANAQAMADQLQKRGFDLVSGGTDNHLMLVDLRSIAMTGKVGDQLLGEINITANKNTVPFDPESPFVTSGLRLGSPAMTTRGMQEDEFRTIANIIADRLLSPEDEGVKADCLRRVSELCAGFPLYDHLRIPVAVIA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.