PharMolix/UniProtQA huggingface dataset:
Protein: RGF1B_HUMAN
Sequence: MPQTPPFSAMFDSSGYNRNLYQSAEDSCGGLYYHDNNLLSGSLEALIQHLVPNVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCVEHQRLSDPDSDKNQMRKIAPKILQLLTEWTETFPYDFRDERMMRNLKDLAHRIASGEEQTYRKNVQQMMQCLIRKLAALSQYEEVLAKISSTSTDRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYSERKKTRNLEAYVEWFNRLSYLVATEICMPVKKKHRARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGAAQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKILQYLLTVPVFSEDALYLASYESEGPENHIEKDRWKSLRSSLLGRV
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
What are the official names of this protein?
Ras-GEF domain-containing family member 1B, GPI gamma-4.
What are the subcellular locations of this protein?
Early endosome. Late endosome. Midbody. Note=May shuttle between early and late endosomes (By similarity). Localizes to midbody at telophase.
Protein: PURL_RHOJR
Sequence: MSAHPVDTVTAATATPDVAQPFKELGLKDDEYARIKEILGRRPTEAELAMYSVMWSEHCSYKSSKVHLKYFGETTTDEMRSSMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPIAVMDQLRFGAADAPDTRRVVDGVVRGVGGYGNSLGLPNVGGETVFDESYAGNPLVNALCAGAMRVEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASETFDGDESGTGRKKLPAVQVGDPFTEKVLIECCLELYAAKLVVGIQDLGGAGLSCATSELAAAGDGGMHINLEQVPMRATGMTAAEVLSSESQERMCAVVTPDNVDAFMEVCKKWDVLATVIGEVTDGERLTISWHGETVVDVPPRTVAHEGPVYERPVQRPASQDALVANTTAGLTRPESADELKATLLKMLASPALCSRKWITEQYDRYVRGNTVLAENADSGVIRVDEKTGRGIALATDASGRYTALDPYAGAQLALAEAFRNVAVTGATPKAVSNCLNFGSPEDPGVMWQFQQAVRGLADGCAKLGIPVTGGNVSFYNQTGSTPILPTPVVAVLGVIDDVHRRIPTGLGLEPGETLILLGDTRDEFDGSIWSQVEHGHLGGVPPKVDLEREQLLADILLAASRDGLVSAAHDLSEGGLAQTVVEAALAGETGCRILLPDDADPFVTLFSESSGRVLVAVPRTEETRFTGMCTARNLPWVRIGVVDEGSDSVEVQGQFSVSLAELRTTFEGTLPALFG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTF2_PONAB
Sequence: MGCDGGTIPKRHELVKGPKKVEKVDKDAELVAQWNYCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSAEKALGKAASHIKSIKNVTELKLSDNPAWEGDKGNTKGDKHDDLQRARFICPVVGLEMNGRHRFCFLRCCGCVFSERALKEIKAEVCHTCGAAFQEDDVIVLNGTKEDVDVLKTRMEERRLRAKLEKKTKKPKAAESVSKPDVSEEAPGPSKVKTGKPEEASLDSREKKTNLAPKSTATNESSSGKAGKPPCGATKRSIADSEESEAYKSLFTTHSSAKRSKEESAHWVTHTSYCF
What is the function of this protein?
Replication termination factor which is a component of the elongating replisome.  Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication.  Might function to facilitate fork pausing at replication fork barriers like the rDNA.  May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion.  Interacts with nascent DNA.
What are the official names of this protein?
Replication termination factor 2, RTF2, Replication termination factor 2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the rtf2 family.
What are the subcellular locations of this protein?
Chromosome. Note=Localizes at the replication fork.
Protein: RL15_CORGB
Sequence: MSEPIKLHDLRPAAGSNKAKTRVGRGEASKGKTAGRGTKGTKARKQVSAAFEGGQMPLQMRLPKLKGFKNPNKVDYQVVNIADLAEKFPQGGDVSIADIVAAGLVRKNELVKVLGNGDISVKLNVTANKFSGSAKEKIEAAGGSATVA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: NRDR_GRABC
Sequence: MRCPFCGHEDTQVKDSRPTDDGTAIRRRRSCTACMQRFTTVERVQLRELIVVKTDQRRVVFDRDKLTRSVQIALRKRPIDPDRIEKMITGIVRQLESSGETEIPSKLIGELVMQTLKEVDDVAYVRFASVYRNFSDAGDFQTFLGGQAASKESDESS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SMA5_CAEEL
Sequence: MVFADFLEKIKSLFAKTKDPITSMSPPQENRSPKAEYLNNFFNTNPTNGKSRGSQEAPRKPLGQTNLNVQGSMPAKKEGFNRVLDGLKKRQLQHDFKLERAAETYEPTQNIGSGAFGIVCEAVETSSNQKVAIKKVAHASATPTLARRTLREIRVLRYINHPNIVPLRDIFRTKGPLGIDVFLVMDLMQNNLHHIIYGNEDPLEEHYINAFLGQLLRGLEYLHAACIAHRDLKPSNLLVNQDGTLRIADFGMAKCADNSSKKHDDEEHCYYMTQHVATLPYRAPELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLTMLGQPPQEVINEVRCDRTRKLIQDFGRKADAEWDDIMFCKARGDDQIVRGNCDTIDFVKQLFQYDAQKRINIQDALLHPYIQRVIPAEAPQKKCPFRVKKDMMQVEDLNHQELISMMKQDVRSAENPITYSELHSGDSTGSTSDMSTNTSGEYSPIAQHEQLLEDVATQISICEPTCDL
What is the function of this protein?
Serine/threonine-protein kinase involved in the postembryonic regulation of body size, mainly through control of cell growth.  In particular, controls the volume of intestine, muscles and hypodermis.  In addition, regulates growth, intestinal granule distribution, lifespan and number of offspring.
What are the official names of this protein?
Mitogen-activated protein kinase sma-5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: EX7L_STRZT
Sequence: MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYFSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGNYSIIIEKAEPDGVGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEKRMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_HELPY
Sequence: MKYTELKDKSIKELEELLHAKKAELFELRVKLKAMQLSNPNEIKKARRNIARINTAINAHYSSSVE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: TRPC_STRP4
Sequence: MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDRLQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREISSQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLVETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTGQDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: NUOB_SALPA
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLHDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQPERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: G6PI_LEGPA
Sequence: MIRNSMKSHTELLSWNLLQKEADRVRLNSDSLTCVVPDSNNYESSKQINCIEYDYSRQRVNRTIIDLLIDLANEVKLQEKIDNLINGKKINISENRPALHTALRDLGNKSIMIDGLDIMSAVINTREKIKVISNQIREKKWLGHSGLPITDIVNIGIGGSDLGPRVCINALSNYISKEFNYHFISDVDPASFNDVIAKINPQTTLFIVSSKSFTTKETLLNARKAFALYEDTASIDQHFIAVTAHPERAYQMGIKTVLPIWDWVGGRFSFCSAVNLITAIAIGYEQFVELLAGAHDVDTHVQFTDFKNNIPVLMALIGIWNNNFLNIHNLLILTYSKKLEYFVPYVQQLDMESNGKSIDVNGSMVDYATGPIVWGGLGNQAQHSYFQLLCQGTHRCVGDFITLKTNDEHEINSMCHYKMKVLSEGIQTIENPYGYIPGNMPMNHLILSDCSPYTLGALVALYEHKIFVQSVIWNINPFDQPGIESAKSAHREITLSSES
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIXB_SALPA
Sequence: MNKFSSVWVFSDTPSRLPELMSGAQAVGEKVNAFVLNEADSATACHLGADHVWLLSGKPEDRMIEDYAAAMAETIRQHSEGGAVLLPNTRRGKLLAAKLGYRLSAAVSNDASDVSLQDGKAAVKHMVYGGLAIGAETIASPFAVITLSSGTFDAQQPDASRSGEMHTVQWQAPATAVTRTATQARQSNSVDLDKARLVVSVGRGIGSKENISLAEALCQTIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANGAQTIFAINKDKNAPIFQYADFGIVGDALKILPALTAALAR
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: PQQC_ACIBS
Sequence: MTQTPEALTTEQFKQAIIDKGQYYHIYHPFHVMMYEGKATQQQIQAWVANRYYYQINIPLKDAAIMANCPDQRVRQEWIQRMIDQDGEYPDGGGREAWLRLAEAVGLSREQVISEELVLPGVRFAVDAYVNFARRASWREAASSSLTELFAPQIHQSRLESWPQHYPWIDDKGYEYFRSRLSQARRDVEHGLTITLDSFTTHEQQQRMLEILQFKLDILWSILDALTLAYVHNEAPYHSVTQERVWHKGLFK
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: KAD_WIGBR
Sequence: MRIILIGSPGSGKGTQAKIMSKKYNLPHISCGDILRKQNKCCDINKLIKKGELINDKLVTNIVLEKLKNINLFKGFILDGFPRTLYQANSIKENKIKIDYVLELFLQEKYIYERVLGRIIDKVSGEIYHLKFNPPKFITEKSNKNKILVRRLDDKKSALQKRINDFFKNSCLISEFYKKESLEKKLKYKIINADFDINTISNKIFNIINV
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARD2_MYCTO
Sequence: MVVNRALLASVDALSRDEQIELVEHINGNLAEGMHISEANQALIEARANDTDDAHWSTIDDFDKRIRARLG
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.
What are the official names of this protein?
Antitoxin ParD2.
Protein: LGT_STRPQ
Sequence: MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMFIEGSYRIPTFLYESFWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 3MGH_RICBR
Sequence: MNNKLIPLSREFFARDTNIVSQELLGKVLYFQGKTAIITETESYIGQDDPACHAARGRTKRTDIMFGPAGFSYVYLIYGMYYCLNFVTETDGFPAATLIRGAYIISTKDLYTADTSKVGSQISGETARRILIREHRRIPKFDVPNLEVSKVDGPGKLCKYLGINISHNKIDLINNNEFFVSDINLKLPYSTTTRIGITKGIDKLWRYVVTNPIDLTKISF
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: BMP2_RAT
Sequence: MVAGTRCLLVLLLPQVLLGGAAGLIPELGRKKFAGASRPLSRPSEDVLSEFELRLLSMFGLKQRPTPSKDVVVPPYMLDLYRRHSGQPGALAPDHRLERAASRANTVLSFHHEEAIEELSEMSGKTSRRFFFNLSSVPTDEFLTSAELQIFREQMQEALGNSSFQHRINIYEIIKPATASSKFPVTRLLDTRLVTQNTSQWESFDVTPAVMRWTAQGHTNHGFVVEVAHLEEKPGVSKRHVRISRSLHQDEHSWSQVRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis.  Induces cartilage and bone formation.  Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2.  Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A.  In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.  Can also signal through non-canonical pathways such as ERK/MAP kinase signaling cascade that regulates osteoblast differentiation.  Stimulates also the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A-ATF4 pathway by stimulating EIF2A phosphorylation which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation.
What are the official names of this protein?
Bone morphogenetic protein 2, BMP-2, Bone morphogenetic protein 2A, BMP-2A.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCKG_CORGB
Sequence: MTTAAIRGLQGEAPTKNKELLNWIADAVELFQPEAVVFVDGSQAEWDRMAEDLVEAGTLIKLNEEKRPNSYLARSNPSDVARVESRTFICSEKEEDAGPTNNWAPPQAMKDEMSKHYAGSMKGRTMYVVPFCMGPISDPDPKLGVQLTDSEYVVMSMRIMTRMGIEALDKIGANGSFVKCLHSVGAPLEPGQEDVAWPCNDTKYITQFPETKEIWSYGSGYGGNAILAKKCYALRIASVMAREEGWMAEHMLILKLINPEGKAYHIAAAFPSACGKTNLAMITPTIPGWTAQVVGDDIAWLKLREDGLYAVNPENGFFGVAPGTNYASNPIAMKTMEPGNTLFTNVALTDDGDIWWEGMDGDAPAHLIDWKGNDWTPESDENAAHPNSRYCVAIDQSPAAAPEFNDWEGVKIDAILFGGRRADTVPLVTQTYDWEHGTMVGALLASGQTAASAEAKVGTLRHDPMAMLPFIGYNAGEYLQNWIDMGNKGGDKMPSIFLVNWFRRGEDGRFLWPGFGDNSRVLKWVIDRIEGRVGADETVVGHTAKAEDLDLDGLDTPIEDVKEALTAPAEQWANDVQDNAEYLTFLGPRVPAEVHSQFDALKARISAAHA
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_STRT1
Sequence: MTKGILGKKVGMTQIFTEAGEFIPVTVIEATPNVVLQVKTVETDGYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGSEITVDIFEAGDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKHLAGRMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SYE1_EHRCR
Sequence: MITRFAPSPTGYLHVGNVRTALVCWLYARKQNGKFLLRFDDTDTQRSKDEYIREIENDLVWLNINWDSSFRQSSRFDRYEDVFNYLLKEGLIYPCYESKEELEFKRKMKLKLGLPPIYDRSALNLTQAEKDKYSERAPYFRFKIDQNQLISWNDEVRGKVSFNSENISDPIIRRVDGTYTYMLPSIIDDMDFNVTHIIRGEDHISNTAVQIQMLHALKASIPIFSHLSLLYSDDNKISKRVGGSSVKDMQSYGLEPMAINSYFAKIGTSNPVSVHTRMCGLIDSFDITTFSQAPTKFNIDDVLKLNPKVLCSMSFDDVRNRLQSFNITSPSFWNFVCGNIDKFSDIEGWAKICSGDMIPVIGQDDKDFIMLALNMLPQGEVRDNTWNLWISNIKQHTDRRAKNLFTPLRLALTGLSTGPELAKLLPLIGRVEIVRRLSYSEVQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_NITSB
Sequence: MLMPKKTKYRKQQKGRNRGKAYNGNSLAFGTIGIKALEHGRIDSRQIEAARVAMTRKVKRTGKIWIRVFPDKPLTKKPLETRMGKGKGSVEKWVMNIKPGRIIYEMAGVEESLAREALDLARYKLPFKTKIVTQESENEIY
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CBIA_LISIN
Sequence: MNKILIAAASSGAGKTTVTLGIMQALKKRGFAVQPFKVGPDYIDTNYHQAITGVASINLDSFLIDDDEMLASLFQKHGESADISVIEGVMGLFDGLGTDRDNASTSFIAKCTKTPVILVVDGKAISTSAAAIVDGFNRFDPELKIAGVIINRVASENHFSLIKGAIERYTDVPVLGYLPKNAAVALPERHLGLVPQEEMTELEAKWELLSDLITTHVDLDKLLEISKSSENLSTSKAQMKVADFSGLRVAYALDAAFHFYYQDNLDLIRLTGAELIPFSPLEDNEVPEADFIYIGGGFPEIFAKQLNDNRSMRKSILAAHEKGIPIYAECGGLMYLGSSLEMEGKQYEMVGVFNGISKMTTRLRKFGYCIAEPLEETLIGKKGMSIRGHEFHHSVFETTETACMKLSKKRDGEIVKEWRGGYQKGNTFASYLHIHFYQNPAILMQMFGAGKR
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: DXS_PARP8
Sequence: MYDLLKTIDDPADLRRLDRRQLQPLADELRAFVLDSVSQTGGHLSSNLGTVELTIALHYVFDTPRDRIVWDVGHQTYPHKILTGRRDQMSTLRQLGGISGFPKRDESPYDTFGTAHSSTSISAALGMAIGSKLRGDDRFAIAVIGDGAMTAGMAFEAMNNAGVEDDVPLLVILNDNDMSISPPVGALNRHLARLMSGRFYAAARAGVERVLRHAPPVLDLARKLEEHAKGMIVPATLFEEFGFNYIGPIDGHDLDSLIPTLQNIKELRGPQFLHVVTKKGQGYKLAEADPVLYHGPGKFNPAEGIKPSTTPAKKTYTQVFGEWLCDAAELDSRVVGITPAMREGSGMVEFEKRFPDRYYDVGIAEQHAVTFAGGLATEGMKPVVAIYSTFLQRGYDQLIHDVALQNLPVVFAIDRAGLVGADGATHAGAYDLAFMRCIPNMTIMAASDENECRQMLYTALQQPNPTAVRYPRGAGTGVATVKQMAALPLGKGEVRRQSTQPAGKRIAILAFGTMVAPSLAAAEQLDATVANMRFVKPIDAALVRELAETHDAVVTVEEGCVMGGAGSACVEAMMESGVIRPVLQLGLPDRFIDHGDPAKLLASCGLDAAGIAKSIRERFVEHASGKSVKRVA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: AROQ_MYCLE
Sequence: MTMVNIINGPNLGRLGRREPDVYGSTTHEQLSALIERAAVEFGIKAVVRQSDSESQLLDWIHLAADAGEPVILNAGGLTHTSVALRDACAELSAPFIEVHISNVHAREEFRRHSYLSPLATGVITGLGVQGYLLALRYLAEIAGN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: PROB_METBF
Sequence: MTDRNEFLNDINKIVIKIGTSSLTKQNCDSTKENCSIDPTFIENIAAQVSELRKLGKEVIVVSSGAIGVGLYELGIAPKPREIPIRQAAAAVGQSILMQYWSEAFSKHGIKVAQILLTYEFYSDRVSYLNLRNSISTLLEYGVVPIINENDCTCTNEIEAIFGDNDKLSAMVASKIDADLLIILSDIDGLFDKNPKIHEDARLISLVEKITPEIESYGGDPTSFKGVGGMRTKIKAAKICSMAGCYVLIANSEIEDVLLKVLSGKEIGTLFLAERHIQKNRARWIILSRASGTIRVDAGAKAAVLGKNSLLSAGVVDVEGNFDRGDVVRLECEGRVFAKGITDYTSEELMKIKGAHTDEIEGILGYNNYSNVIKKENIGIMEN
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_BACAA
Sequence: MISVNDFRTGLTIAVDNGLWQVLDFQHVKPGKGAAFVRSKLRNLRTGSVQEKTFRAGEKVEKAHIENRRMQYLYASGEAHVFMDNGTYEQIELGEKQIERELKFLKENMEVSIMTYQGEVLGVELPNTVELQVTETEPGIKGDTASNVTKPATLETGLVVQVPIFINEGEMLIINTGEGKYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHCA_ANASL
Sequence: MVKTPITEAIAAADTQGRFLS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
C-phycocyanin alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of the phycobilisome rod.
Protein: UVRC_PROMA
Sequence: MRSLNDNLPLILDPTRLKTTLDNIPKAPGCYLMKDNEDNIIYIGKSINLNSRVKSYFRRRNDNNPKNSLMLKQVSLIDFIVTDNELEALNLESNLIKSNQPHYNILLKDDKKYPYLCITWSEDYPRILIVRRRRNRADKDRYYGPYVDVTSLRNTLFLIKKIFPLRQRQRPLYKDKTCLNYSIGRCPGVCQKIISSSDYRTVIKKVEMIIQGRTSELKKLLEEKMHIYSKEMKYEEALKIKNQLSGLNTFSQTQKITEPDSSINRDVIAHASNDSNTSIQLFQIRAGKLIARLAFTADSIKTNKENIIQKVIEEHYSQLDPVVIPKEILLDNQIEKIEVISEWLSEMKGSKVNIKIPKISKKANMVSLVKKNAELELTKLSKGVEKANLALEELAELLDLPFKPRRIEGYDISHIQGSDAVGSQVVFVEGMPAKHHYRKFIIKDETIKLGHSDDYLSIYELITRRFSRWSKYKEKGVNLSDIRNYKSSILDPSTLADFPDLVMIDGGKGQLNIALKALEKLNLSEDIKLCSLAKKNEDIFIPGNNKPLKCNNDDNGLLLLRRLRDEAHRFAVTFHRKRRTLGMRRTELTEIPGIGPKRIKALLLHFNSVQAIKMARKEEIASAPGVGRELAEHIWNYFNK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.