PharMolix/UniProtQA huggingface dataset:
Protein: CHMP1_ORYSJ
Sequence: MGNPEKLMTQIFDLKFTSKSLQRQARKCEKEEKEQKLKVKKAIEKGNMDGARIYAENAIRKRTEHMNYLRLASRLDAVVARLDTQAKMQVIGKSMANIVKSLDSALATGNLQKMSETMDNFERQFVNMEVQAEFMEGAMAGSTSLSTPETEVNSLMQQVADDYGLEVSVGLPQAAAHAIPAAKEKEKAVDEDDLSRRLAELKARG
What is the function of this protein?
Involved in ESCRT-dependent multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
What are the official names of this protein?
ESCRT-related protein CHMP1, Protein CHARGED MULTIVESICULAR BODY PROTEIN 1, Protein CHROMATIN MODIFYING PROTEIN 1.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: PRIMA_MOUSE
Sequence: MLLRDLVPRHGCCWPSLLLHCALHPLWGLVQVTHAEPQKSCSKVTDSCQHICQCRPPPPLPPPPPPPPPPRLLSAPAPNSTSCPAEDSWWSGLVIIVAVVCASLVFLTVLVIICYKAIKRKPLRKDENGTSVAEYPMSSSQSHKGVDVNAAVV
What is the function of this protein?
Required to anchor acetylcholinesterase (ACHE) to the basal lamina of the neuromuscular junction and to the membrane of neuronal synapses in brain.  Also able to organize ACHE into tetramers.
What are the official names of this protein?
Proline-rich membrane anchor 1, PRiMA.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction. Synapse. Note=In the brain, PRIMA linked to ACHE is found in membrane rafts.
Protein: TATA_DEIDV
Sequence: MLGFGPFELILIVVIIALLFGARKLPELGKGMGRGIKEFKQEMHEPSPPRPQVTDIPSQRLDPVTGAPVSTESTVPASDRRS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FGFR1_CHICK
Sequence: MFTWRCLILWAVLVTATLSAARPAPTLPDQALPKANIEVESHSAHPGDLLQLRCRLRDDVQSINWVRDGVQLPENNRTRITGEEVEVRDAVPEDSGLYACMTNSPSGSETTYFSVNVSDALPSAEDDDDEDDSSSEEKEADNTKPNQAVAPYWTYPEKMEKKLHAVPAAKTVKFKCPSGGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENKYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFVCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGISHHSAWLTVLEATEQSPAMMTSPLYLEIIIYCTGAFLISCMVVTVIIYKMKSTTKKTDFNSQLAVHKLAKSIPLRRQVTVSADSSSSMNSGVMLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLILGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGMEYCYNPTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVAMTSNQEYLDLSVPLDQYSPGFPATRSSTCSSGEDSVFSHDPLPDEPCLPRCPPHSHGALKRH
What is the function of this protein?
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.  Required for normal mesoderm patterning and normal skeletogenesis.  Phosphorylates PLCG1, FRS2, GAB1 and SHB.  Ligand binding leads to the activation of several signaling cascades.  Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate.  Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway.  Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2.  In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription.  FGFR1 signaling is down-regulated by ubiquitination, internalization and degradation (By similarity).
What are the official names of this protein?
Fibroblast growth factor receptor 1, FGFR-1, bFGF-R-1, Basic fibroblast growth factor receptor 1, Tyrosine kinase receptor CEK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm, cytosol. Cytoplasmic vesicle. Note=After ligand binding, both receptor and ligand are rapidly internalized. Can translocate to the nucleus after internalization, or by translocation from the endoplasmic reticulum or Golgi apparatus to the cytosol, and from there to the nucleus (By similarity).
Protein: DRE2_ACYPI
Sequence: MSDRKNVLFVVGKSSAVKELEEFASCNADRANVKIEIVENIGLATDGPLYSAILSGFGADDNVSCDLNLLPTYTTLLTAGGTLIAKTDVGTEDALVKRMKLCGFLNVAKSESVPGVVVGNMPTYKVGSSDKVTLNPEMKENVVSAWKLDDNNSETISEDDLLEADDLIKPDSSSLRVCATTKKAKACKDCSCGLAEELEANRLKDTPKPDTSNAKSSCGSCYLGDAFRCASCPYLGMPAFRPGEKVQLAGNLLQDDF
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: PYRB_PROMP
Sequence: MGNWPHKHILTLSNFSIDDYESVIELTERFKSLNNAGTKKIPALQGKLITSIFFEASTRTRNSFELAAKRLSADVQSFSPSSSSLSKGETLIDTALTYAAMGSDILVIRHSSSHVPLEISKKLDASKAKTSVLNAGDGLHSHPSQGLLDLYTLIKFFSPKLLKPEILNSKKILIVGDVIHSRVARSNLWALTAFGANIILCGPPTLIPEEFTDFVSSSPPNQLRDPISSRGSITISSSLEESIKCADAVIVLRLQKERMIENLLSSIKSYSENYCLTPEKLSLNCKDIPILHPGPINRGIEISSRVVDEYPNCLINDQVSNGIPTRMALLYLLSKFNN
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL19_LEGPH
Sequence: MTNIIDQINAEQMQGKEIPDFNPGDTVLVQVKVIEGNRERLQAFEGVVIAKRNRGLNSAFTVRKISHNVGVERVFQTYSPIVDSITVKRRGDVRRAKLYYLRNLAGRAARIKEKLSGKKGD
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: YIDC_BURM7
Sequence: MDIKRTVLWVIFFMSAVMLFDNWQRSHGRPSMFFPNVTQTNTASNATNGNGASGASAAAAANALPAAATGAAPATTAPAAQAQLVRFSTDVYNGEIDTRGGTLAKLTLTKAGDGKQPDLSVTLFDHTANHTYLARTGLLGGDFPNHNDVYAQVAGPTSLAADQNTLKLSFESPVKGGVKVVKTYTFTRGSYVIGVDTKIENVGAAPVTPSVYMELVRDNSSVETPMFSHTFLGPAVYTDQKHFQKITFGDIDKNKADYVTSADNGWIAMVQHYFASAWIPQSGAKRDIYVEKIDPTLYRVGVKQPVEAIAPGQSADVSARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGFVGNWGWAIVLLTLLIKAVFFPLSAASYKSMARMKEITPRMQALRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWVLWIHDLSQRDPYFILPVLMAVSMFVQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRTLGGAAAKKKAS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KAD_LEIXX
Sequence: MLIVGPPGAGKGTQASRITSGYGIPDISTGDIFRANIKNKTELGQQVKAIVDAGDYVPDSLTNELVTGRLAEDDAKGGFLLDGYPRTLEQVKYLDELLGSDGEKLDAVIQLVADREEIVARLTKRAREQGRADDSEEAIRYRQEVYVRETSPLIEVYRERGLLVEVDGLGPVDEVAGRICTALAERGILPLTGTGESVA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_PECCP
Sequence: MTLHTSPILHSLLDTDAYKLHMQQAVYHHYYDVDVAAEFRCRGDELLGVYADEIAHQVDLMRFLSLNDDEFTYLSSLPFFKPDYLHWLRGFRFNPQQVSIKNNAGKLDIRITGPWREVILWEVPLLAVISEVVHRHRSPNVTAEQALVQLSASLESFRQHSADVDLSQFKLMDFGTRRRFSRDVQQTIVTALQADFPYLIGTSNYDLARRLDITPVGTQAHEWFQAHQQISPTLANSQRAALQMWLREYPSHLGIALTDCITMDAFLRDFDLPFAEAYQGLRHDSGDPVDWGEKAIAHYQRLNIDPMSKTLVFSDNLNLDKALALYRHFGQRVNLVFGIGTRLTCDIPGVKPLNIVIKLVECNGKPVAKLSDSPGKTICQDQNFVCELRKAFDLPRVKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: TRMN6_ALIF1
Sequence: MSKSFTFKQFHIDIGSCGMPVSTDGVLLGAWADIRACSQILDIGAGTGLLSLMSAQRNSDAHIDAIELMPIAADVARLNFYQSPWKERLTLIHHDFLTYQAPHKYDAIICNPPYFNNGEQSQKGERSTARHTDSLPFDKLLQHCKTLISPTGRASFILPVFEGELFIKVAKNDDFHLTKITKVKTTEKKSPTRLLIELSLFPHIYQESTLTIHDGNGYSDDFIKLTRTFYLNMD
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNTD1_HUMAN
Sequence: MDGPMRPRSASLVDFQFGVVATETIEDALLHLAQQNEQAVREASGRLGRFREPQIVEFVFLLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQPRDNKRESQNWRALKQQLVNKFTLRLVSCVQLASKLSFRNKIISNITVLNFLQALGYLHTKEELLESELDVLKSLNFRINLPTPLAYVETLLEVLGYNGCLVPAMRLHATCLTLLDLVYLLHEPIYESLLRASIENSTPSQLQGEKFTSVKEDFMLLAVGIIAASAFIQNHECWSQVVGHLQSITGIALASIAEFSYAILTHGVGANTPGRQQSIPPHLAARALKTVASSNT
What is the function of this protein?
Plays a role in the different steps of crossover formation during meiotic recombination.  Participates in the crossover differentiation step of crossover-specific recombination intermediates through its interaction with PRR19.  In addition, stimulates crossover formation through the interactions with RFC3 and RFC4 and simultaneously regulates cell-cycle progression through interactions with CDC34 and subsequent ubiquitination of WEE1.  May also participates in an active deselection process that destabilizes or removes excess pre-CO intermediates.
What are the official names of this protein?
Cyclin N-terminal domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=Shuttles between the nucleus and cytoplasm in a stage-specific manner of prophase I cells. Co-localized at crossover sites with PRR19.
Protein: METK_THEVB
Sequence: MRYLFSSESVTEGHPDKICDQIADAILDALLTQDPQSRVAAEVVVNTGLVLITGEITTKAQVNYVNLARQKIHEIGYTDANNGFAANSCAVLVALDEQSPDIARGVDTAQEAREQLSDAELDRIGAGDQGIMFGYACNETPEYMPLPISLAHRMARRLAAVRKTGQLPYLRPDGKTQVTVIYEDGKPVGIDTILISTQHTATIDDISEESAVQAKIKADLWEAVVKPVFADLTLQPDGNTRFLVNPTGKFVIGGPQGDSGLTGRKLVVDTYGGYARHGGGAFSGKDPTKVDRSAAYMARYIAKNIVAAGLADKCELQISYAIGVARPMSLFVDTFGTGKLSPEQLLELIKTHFDLRPAAIIQTLNLRHLPQERGGRFYQDVAAYGHFGRHDLDLPWEKLDKVADLQAAAAQFLSAV
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM23_PONAB
Sequence: MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTVAAFGAMNGLRLGLKETQNMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGGLRGIARGGLTGLTLTSLYALYNNWEHMKGSLLQQSL
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim23.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLYR1_PONAB
Sequence: MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTATEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWDRTAEKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPRKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH
What is the function of this protein?
Cytokine-like nuclear factor with chromatin gene reader activity involved in chromatin modification and regulation of gene expression.  Acts as a nucleosome-destabilizing factor that is recruited to genes during transcriptional activation.  Recognizes and binds histone H3 without a preference for specific epigenetic markers and also binds DNA.  Interacts with KDM1B and promotes its histone demethylase activity by facilitating the capture of H3 tails, they form a multifunctional enzyme complex that modifies transcribed chromatin and facilitates Pol II transcription through nucleosomes.  Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300.  With GATA4, co-binds a defined set of heart development genes and coregulates their expression during cardiomyocyte differentiation.  Regulates p38 MAP kinase activity by mediating stress activation of MAPK14/p38alpha and specifically regulating MAPK14 signaling.  Indirectly promotes phosphorylation of MAPK14 and activation of ATF2.  The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6.
What are the official names of this protein?
Cytokine-like nuclear factor N-PAC, NPAC, Glyoxylate reductase 1 homolog, Nuclear protein NP60, Putative oxidoreductase GLYR1.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. NP60 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Found in actively RNAPolII-transcribed gene bodies.
Protein: RK33_ADICA
Sequence: MANTKDARVTIALECTSCIQRKTSGKSAGLCRYTTRKNRRNTPARLELEKYCFHCHKHTLHKESKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LINA_STAHA
Sequence: MKNNNVTEKELFYILDLFEHMKVTYWLDGGWGVDVLTGKQQREHRDIDIDFDAQHTQKVIQKLEDIGYKIEVHWMPSRMELKHEEYGYLDIHPINLNDDGSITQANPEGGNYVFQNDWFSETNYKDRKIPCISKEAQLLFHSGYDLTETDHFDIKNLKSIT
What are the official names of this protein?
Lincosamide resistance protein.
Protein: FSAB_ECO57
Sequence: MELYLDTANVAEVERLAHIFPIAGVTTNPSIIAASKESIWEVLPRLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIPGIVVKIPVTSEGLAAIKILKKEGITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPESMVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTTHL
What is the function of this protein?
Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
What are the official names of this protein?
Fructose-6-phosphate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLAE_ECO57
Sequence: MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLLVRQLYNVGVLSMLIIVVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPVVAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTVIFVAVGIWGGSLVGVSWKGIDSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISLFNGYDAIPTSAGISRATTRTVVHSSLAVLGLDFVLTALMFGN
What is the function of this protein?
Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Intermembrane phospholipid transport system permease protein MlaE.
What is the protein family that this protein belongs to?
Belongs to the MlaE permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTS_AGRVS
Sequence: MTEITAAMVKELREKSGAGMMDCKKALAENGGDMEASIDWLRAKGIAKADKKSGRTAAEGLIGIASSGTTAVVVEVNSETDFVARNDAFQDMVRGISNVALSTDGTVDSINAATYAATGKSVSDSIKDAIATIGENMALRRATQLKVEDGVVATYVHNAVADGLGKLGVLVALKSTGNKEALNTIGRQIAMHVAATNPLAVRAEEVDAAVAERERNVFIEQSRESGKPENIIEKMVEGRMRKFFEDVALLSQAFVINPDLTVAAALKEAEKDVGAPIEITGIARLLLGEGIEKEESDFAAEVAAVAKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REC19_HUMAN
Sequence: MNPSEMQRKAPPRRRRHRNRAPLTHKMNKMVTSEEQMKLPSTKKAEPPTWAQLKKLTQLATKYLENTKVTQTPESMLLAALMIVSMVSAGVPNSSEETATIENGP
What is the function of this protein?
Retroviral replication requires the nuclear export and translation of unspliced, singly-spliced and multiply-spliced derivatives of the initial genomic transcript.  Rec interacts with a highly structured RNA element (RcRE) present in the viral 3'LTR and recruits the cellular nuclear export machinery.  This permits export to the cytoplasm of unspliced genomic or incompletely spliced subgenomic viral transcripts (By similarity).
What are the official names of this protein?
Endogenous retrovirus group K member 19 Rec protein, HERV-K(C19) Rec protein, HERV-K_19q11 provirus Rec protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between the nucleus and the cytoplasm. When in the nucleus, resides in the nucleolus (By similarity).
Protein: LFG1_MOUSE
Sequence: MSHEKSFLVSGDSYPPQNIVGPQAPMPPYVQAPYPGAPYPQAPFQPSPYGQPGYPHGPSPYPQGGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPPPFQDPGSPQHGNYQEEGPPSYYDNQDFPAVNWDKNIRQAFIRKVFLVLTLQLSVTLSTVAIFTFVGEVKGFVRENVWTYYVSYAIFFISLIVLSCCGDFRRKHPWNLVALSILTVSLSYMVGMIASFYNTEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGVLLVSVVVLFIFAILCIFIRNRILEIVYASLGALLFTCFLAVDTQLLLGNKQLSLSPEEYVFAALNLYTDIINIFLYILTIIGRAKE
What is the function of this protein?
Potential apoptotic regulator.
What are the official names of this protein?
Protein lifeguard 1, Glutamate [NMDA] receptor-associated protein 1, NMDA receptor glutamate-binding subunit.
What is the protein family that this protein belongs to?
Belongs to the BI1 family. LFG subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ANMK_PASMU
Sequence: MKEATMYYIGVMSGTSLDGVDLALMDFSCAQPQLIHADFYPMPPAIRQQISTLCNSGTTTLQALGELDHQLGLLYTDCIQQFLQKHRLSPEQITAIGCHGQTVWHSPNSHYPFTMQIGDANLIAAKTGITTVADFRRKDMAFGGQGAPLVPAFHQALFRKPNQATVVLNVGGISNISRLLPNEEVIGYDTGPGNTLLDAWIEKHQGKAYDKNAEWAKSGKVNTDLLADLLDEPFFALPAPKSTGRELFNLAWLNKKLQKHTALLPQDVQATLVELTAQSIVDQLNQIETELDRHLLVCGGGVKNCLLMARLTALLPQWQVQTTNDYGLDADYVEAAAFAWLAYQRLNDLPGNLPSVTGAKSAVSLGAIYPKEKDVAA
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: GLYA_TRIL1
Sequence: MSILSQFDPAVAEAIQHETERQEYNLELIASENFVSEAVLEAQGSVMTNKYAEGYPGKRYYGGCHHVDVVENLAIERAKELFGAEHANVQPHAGSQANMAVYNAVCQPGDTILGMNLSHGGHLTHGSPVNFSGRFYNVVPYGVSPDTETIDYNEVERLALEHKPKMIVVGASAYPRIIDFPAFRAIADKVGAKVMVDMAHIAGLVAAGVHPNPVPYAEFVTTTTHKTLRGPRGGMILCREEYAKTINSQIFPGIQGGPLMHVIAAKAVAFKEALQPEFKTYQQQIVKNAAKLAECLMAKGFKLTSGGTDNHLMLINFTGTEITGKAAEEALDKAGITVNKNTVPFETRSPFVTSGIRVGTPACTSHGLKETEMEQVAGFIADAVANIGNDEALAAIQKRVNELMKKFPLYASRLK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATB_HELPH
Sequence: MFGMGFFEILVVLVVAIIFLGPEKFPQAVVDVVKFFRAVKKTLNDAKDTLDKEINIEEIKKETLEYQKLFENKVESLKGVKIEELEDAKITAENEIKSIQDLMQDYQRSLETNTIPNHLNEEVSNEEALNKEVSSDESPKEVQLATDNNTKEHDKEKEHV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.