PharMolix/UniProtQA huggingface dataset:
Protein: NDUAD_GORGO
Sequence: MGASKVKQDMPPPGGYGPIDYKRNLPRRGLSGYSMLAIGIGTLIYGHWSIMKWNRERRRLQIEDFEARIALLPLLQAETDRRTLQMLRENLEEEAIIMKDVPDWKVGESVFHTTRWVPPLIGELYGLRTTEEALHASHGFMWYT
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.  Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death.  This apoptotic activity is inhibited by interaction with viral IRF1.  Prevents the transactivation of STAT3 target genes.  May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, Complex I-B16.6, CI-B16.6, NADH-ubiquinone oxidoreductase B16.6 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA13 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. Nucleus. Note=Localizes mainly in the mitochondrion. May be translocated into the nucleus upon IFN/RA treatment.
Protein: ARGB_BARHE
Sequence: MDDVENGVADVFEKQAAFLSSALPYMQKYENETVVVKYGGHAMGDPALGRAFARDIALLKQSGINPVVVHGGGPQIAEILMKMGIESRFENGLRVTDERIVEVVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAEKAYKTVIDPDSHIERVLDLGFVGEPVEVDRTLLDLLACSEMIPVLAPVAPGRDGKTYNINADIFAGAIAGALEAKRLLFLTDVPGVLDKKGKLLKELTISEAENLIKNETISGGMIPKVETCMKALQNGVEAVVILNGRTPHSVLLELFTEQGAGTLIVS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y36K_HALSN
Sequence: MASQPEEGFGERLRKEVTVDTSRGVRATSTAQAVENFEGWYADQRDTQMVVEEATTGERVGFRTPNRFTPEYREMLYAKAQSLERGLREEWGDLLHTAMVTLTASTTEEDGGPRPLVDHLRDLLSSWSAVYDALRHTLEDREFEYLAIIEPTTPAGNGPAGYAHIHLGVFVKGPVVAEQFQDVLDAHVKNSEGAGREAHRAVVEDDEDEAAVSIRRSARPDREDGIENLGAYLAAYMAGEYGVEALAMPAHVRAFYAAMWATGTQWFRPSNGAQRHMQPESDDEESVEEWEMVGIAPEGDLEDEIIEVDPEQPRDDPYRRLRTPPPGG
What is the function of this protein?
Possibly necessary for replication.
What are the official names of this protein?
Uncharacterized 36 kDa protein.
Protein: STRA6_MOUSE
Sequence: MESQASENGSQTSSGVTDDYSSWYIEEPLGAEEVQPEGVIPLCQLTAPPALLHACLASLSFLVLLLLALLVRRRRLWPRCGHRGLGLPSPVDFLAGDLSWTVPAAVFVVLFSNLCLLLPDENPLPFLNLTAASSPDGEMETSRGPWKLLALLYYPALYYPLAACASAGHQAAFLLGTVLSWAHFGVQVWQKAECPQDPKIYKHYSLLASLPLLLGLGFLSLWYPVQLVQSLRHRTGAGSQGLQTSYSEKYLRTLLCPKKLDSCSHPASKRSLLSRAWAFSHHSIYTPQPGFRLPLKLVISATLTGTATYQVALLLLVSVVPTVQKVRAGINTDVSYLLAGFGIVLSEDRQEVVELVKHHLWTVEACYISALVLSCASTFLLLIRSLRTHRANLQALHRGAALDLDPPLQSIHPSRQAIVSWMSFCAYQTAFSCLGLLVQQVIFFLGTTSLAFLVFVPLLHGRNLLLLRSLESTWPFWLTVALAVILQNIAANWIFLRTHHGYPELTNRRMLCVATFLLFPINMLVGAIMAVWRVLISSLYNTVHLGQMDLSLLPQRAASLDPGYHTYQNFLRIEASQSHPGVIAFCALLLHAPSPQPRPPLAPQDSLRPAEEEEGMQLLQTKDLMAKGAGHKGSQSRARWGLAYTLLHNPSLQAFRKAALTSAKANGTQP
What is the function of this protein?
Functions as retinol transporter (PubMed:23839944, PubMed:24852372).  Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1.  Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A (By similarity).  Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin (PubMed:21368206, PubMed:23839944).  Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid and 11-cis-retinal (PubMed:22467576, PubMed:24852372).  STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency (PubMed:22467576, PubMed:23839944, PubMed:24852372).  Does not transport retinoic acid (By similarity).
What are the official names of this protein?
Receptor for retinol uptake STRA6, Retinoic acid-responsive protein, Retinol-binding protein receptor STRA6, Stimulated by retinoic acid gene 6 protein.
Protein: CSLD1_ORYSI
Sequence: MASKGILKNGGKPPTAPSSAAPTVVFGRRTDSGRFISYSRDDLDSEISSVDFQDYHVHIPMTPDNQPMDPAAGDEQQYVSSSLFTGGFNSVTRAHVMEKQASSARATVSACMVQGCGSKIMRNGRGADILPCECDFKICVDCFTDAVKGGGGVCPGCKEPYKHAEWEEVVSASNHDAINRALSLPHGHGHGPKMERRLSLVKQNGGAPGEFDHNRWLFETKGTYGYGNAIWPEDDGVAGHPKELMSKPWRPLTRKLRIQAAVISPYRLLVLIRLVALGLFLMWRIKHQNEDAIWLWGMSIVCELWFALSWVLDQLPKLCPINRATDLSVLKDKFETPTPSNPTGKSDLPGIDIFVSTADPEKEPVLVTANTILSILAADYPVDKLACYVSDDGGALLTFEAMAEAASFANLWVPFCRKHEIEPRNPDSYFNLKRDPFKNKVKGDFVKDRRRVKREYDEFKVRVNGLPDAIRRRSDAYHAREEIQAMNLQREKMKAGGDEQQLEPIKIPKATWMADGTHWPGTWLQASPEHARGDHAGIIQVMLKPPSPSPSSSGGDMEKRVDLSGVDTRLPMLVYVSREKRPGYDHNKKAGAMNALVRASAIMSNGPFILNLDCDHYVYNSKAFREGMCFMMDRGGDRLCYVQFPQRFEGIDPSDRYANHNTVFFDVNMRALDGLQGPVYVGTGCLFRRIALYGFDPPRSKDHTTPWSCCLPRRRRTRSQPQPQEEEEETMALRMDMDGAMNMASFPKKFGNSSFLIDSIPVAEFQGRPLADHPSVKNGRPPGALTIPRETLDASIVAEAISVVSCWYEEKTEWGTRVGWIYGSVTEDVVTGYRMHNRGWKSVYCVTHRDAFRGTAPINLTDRLHQVLRWATGSVEIFFSRNNALFASSKMKVLQRIAYLNVGIYPFTSVFLIVYCFLPALSLFSGQFIVQTLNVTFLTYLLIITITLCLLAMLEIKWSGIALEEWWRNEQFWLIGGTSAHLAAVLQGLLKVIAGIEISFTLTSKQLGDDVDDEFAELYAVKWTSLMIPPLTIIMINLVAIAVGFSRTIYSTIPQWSKLLGGVFFSFWVLAHLYPFAKGLMGRRGRTPTIVYVWSGLVAITISLLWIAIKPPSAQANSQLGGSFSFP
What is the function of this protein?
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
What are the official names of this protein?
Cellulose synthase-like protein D1, OsCslD1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RL7A_NANEQ
Sequence: MAEKPPYVKFEVPEELANKVYELVRKARETGKIRKGTNETTKAVERGQAKLVIIAENVNPPEIVMHLPALCEEKGVPYVYVPSKEELGKAAGINVSAASAAIIDAGEAKDLLEEIIRSVQELKAK
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA1D_CONCN
Sequence: MGMRMMFTVFLLVVLTTTVVSFPSDSASDGRDDEAKDERSDMYELKRNGRCCHPACGKHFNCGR
What are the official names of this protein?
Alpha-conotoxin CnID, [Hyp4]-CnID.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_RUTMC
Sequence: MAKLTNEDILNAIADMSVMNVVELVSAMEEKFGVSAAPVAAPPVVADTIDDVVVEKDEFDVMLTSFGKKKVAVIKMARSITGLGLKEAKDMVESAPVVIKEGASKVEAEDIQKQLEEAGASVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ISPH_GLOC7
Sequence: MDTKAFKRSLQQSENYHRKGFGQEDEAMGVMNSEYQSSLIQEIRNNNYRLTQGDVTIRLAEAFGFCWGVERAVAMSYETRQHFPNQRIWLTNEVIHNPSVNQRLRDMKVEFIPVIEDQKDFSVVERDDVVILPAFGASVTEMQLLNDKGCTIVDTTCPWVAKVWNSVEKHKKRNYTSIIHGKYKHEETVATSSFAGTYLVVLNMEQAKYVCNYILNGGDKQEFLAKFKKAYSEGFDPDTDLERVGIANQTTMLKSETEEIGKLFEHTMLKKYGPLDLNNHFMSFNTICDATQERQDAMLDLVKEKLDLMVVIGGFNSSNTTHLQEISIHHGIVSYHIDSAARIDLNNHIEHKPLGKDLEVKENWLPDGKIVVGVTSGASTPDIVVEQVLQKIFAIKSAVAMV
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: NTRC_RHIME
Sequence: MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYRSSRSA
What is the function of this protein?
Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation.  Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
What are the official names of this protein?
DNA-binding transcriptional regulator NtrC, Nitrogen regulation protein NR(I), Nitrogen regulator I, NRI.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ9_RAT
Sequence: MAATAAVSGVLRRLGWRLLQLRCLPVARCQSPLMPRAFHTAVGFRSSEEQRQQPPHSSQQHSETQGPEFSRPPPRYTDQSGEEEEDYESEEQIQHRILTAALEFVPDHGWTAEAIAEGAQSLGLSSAAASMFGSDGSELILHFVTQCNARLNHVLEEEQKLVQLGQAEKRKTDQFLRDAVETRLRMLIPYIEHWPRALSILLLPQNIPPSLSLLTSMVDDMWHYAGDQSTDFNWYTRRAVLAGIYNTTELVMMQDSSPDFEDTWRFLDNRINDAMNMGHTAKQVKSTGEALVQGLMGAAVTLKNLTGLNQRR
What is the function of this protein?
Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.  Binds a phospholipid of at least 10 carbons in each acyl group.  May be required to present its bound-lipid to COQ7.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COQ9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL27_PSEP1
Sequence: MAHKKAGGSTRNGRDSESKRLGVKMYGGQVIKPGNIIVRQRGTEFHAGYGVGMGKDHTLFAKIEGVIKFEKKGEFMRRYVSIVAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PAND_STAA2
Sequence: MIRTMMNAKIHRARVTESNLNYVGSITIDSDILEAVDILPNEKVAIVNNNNGARFETYVIAGERGSGKICLNGAASRLVEVGDVVIIMTYAQLNEEEIKNHAPKVAVMNEDNVIIEMIHEKENTIVL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_STRTD
Sequence: MSFTIKVKEEIIAASSKDIAELSALIKMSGSVGLTNQGLTLSISTENAKIARHIYQLIENRYRCNPELRHYNKTNLKKNRVYTVFVAENVNDILSDLQLADSFFGFETGIETSIMEDDDAGRSYLRGAFLATGTVRDPEKGRYQLEIFSVYQDHAEDLASLMKKFMLDAKVLQHKNGFVTYLQKAEDIMDFLIVIGAMTSKEIFEEVKIMRETRNDLNRANNAETANIARTISASMKTINNIIKIMDTVGLEILPVELRQIAQLRIANPDYSIQQIADSIEPPLTKSGVNHRLRKINKIADDL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: ATG12_RAT
Sequence: MAEDPEAVLQLPAAPAAAAGESLLELSPETAIPEPPSSVAVSPGTEEPPGDTKKKIDILLKAVGDTPIMKTKKWAVERTRTVQALIDFIRKFLRLLASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG
What is the function of this protein?
Ubiquitin-like protein involved in autophagy vesicles formation.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.  The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS.  Also plays a role in translation or delivery of incoming viral RNA to the translation apparatus (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane.
Protein: ODPB_PORPU
Sequence: MSKVFMFDALRAATDEEMEKDLTVCVIGEDVGHYGGSYKVTKDLHSKYGDLRVLDTPIAENSFTGMAIGAAITGLRPIVEGMNMSFLLLAFNQISNNAGMLRYTSGGNFTLPLVIRGPGGVGRQLGAEHSQRLEAYFQAIPGLKIVACSTPYNAKGLLKSAIRDNNPVVFFEHVLLYNLQEEIPEDEYLIPLDKAEVVRKGKDITILTYSRMRHHVTEALPLLLNDGYDPEVLDLISLKPLDIDSISVSVKKTHRVLIVEECMKTAGIGAELIAQINEHLFDELDAPVVRLSSQDIPTPYNGSLEQATVIQPHQIIDAVKNIVNSSKTITT
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CSA1_ARATH
Sequence: MTSSSSWVKTDGETPQDQVFINFRGVELRKNFVSHLEKGLKRKGINAFIDTDEEMGQELSVLLERIEGSRIALAIFSPRYTESKWCLKELAKMKERTEQKELVVIPIFYKVQPVTVKELKGDFGDKFRELVKSTDKKTKKEWKEALQYVPFLTGIVLDEKSDEDEVINIIIRKVKEILNRRSEGPPSKCSALPPQRHQKRHETFWGIELRIKQLEEKLRFGSDETTRTIGVVGMPGIGKTTLATMLYEKWNDRFLRHVLIRDIHEASEEDGLNYLATKFLQGLLKVENANIESVQAAHEAYKDQLLETKVLVILDNVSNKDQVDALLGERNWIKKGSKILITTSDKSLMIQSLVNDTYEVPPLSDKDAIKHFIRYAFDGNEGAAPGPGQGNFPKLSKDFVHYTKGNPLALQMLGKELLGKDESHWGLKLNALDQHHNSPPGQSICKMLQRVWEGSYKALSQKEKDALLDIACFRSQDENYVASLLDSDGPSNILEDLVNKFMINIYAGKVDMHDTLYMLSKELGREATATDRKGRHRLWHHHTIIAVLDKNKGGSNIRSIFLDLSDITRKWCFYRHAFAMMRDLRYLKIYSTHCPQECESDIKLNFPEGLLLPLNEVRYLHWLKFPLKEVPQDFNPGNLVDLKLPYSEIERVWEDNKDAPKLKWVNLNHSKKLNTLAGLGKAQNLQELNLEGCTALKEMHVDMENMKFLVFLNLRGCTSLKSLPEIQLISLKTLILSGCSKFKTFQVISDKLEALYLDGTAIKELPCDIGRLQRLVMLNMKGCKKLKRLPDSLGQLKALEELILSGCSKLNEFPETWGNMSRLEILLLDETAIKDMPKILSVRRLCLNKNEKISRLPDLLNKFSQLQWLHLKYCKNLTHVPQLPPNLQYLNVHGCSSLKTVAKPLVCSIPMKHVNSSFIFTNCNELEQAAKEEIVVYAERKCHLLASALKRCDESCVPEILFCTSFPGCEMPSWFSHDAIGSMVEFELPPHWNHNRLSGIALCVVVSFKNCKSHANLIVKFSCEQNNGEGSSSSITWKVGSLIEQDNQEETVESDHVFIGYTNCLDFIKLVKGQGGPKCAPTKASLEFSVRTGTGGEATLEVLKSGFSFVFEPEENRVPSPRNDDVKGKVKINKTPSANGCFKDQAKGNESPKGQWQTYIENSSTNIPSEAHSSQKTGFNGFNGMYSVCVLYEMYSH
What is the function of this protein?
TIR-NB-LRR receptor-like protein that functions in photomorphogenic development.  May function downstream of phytochrome B (phyB) signaling.
What are the official names of this protein?
Disease resistance-like protein CSA1, Protein CONSTITUTIVE SHADE-AVOIDANCE 1.
Protein: RS18_GLOVI
Sequence: MTSFGYRGKRVSPIPPKDKIDYKEVDLLRKFITERGKILPRRITGLTAKQQRDLTVAIKRARLLALLPFVNQEG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RPOB_SULDN
Sequence: MLNTLYSGNRLRVDFSKTPQQIEVPNLLQLQQSSYNKFLMLEEKDRSQSGVETVFQSVFPIHDTQNRLTVEYIDSEVGKPKYTVRECMERGLTYAVSLRMKTRLILWDRDENTKEKLGVKDIKEQSIFVRDIPLMTERTSFIINGVERVVVNQLHRSPGVIFKEEESTTSGNKLIYTGQIIPDRGSWLYFEYDPKDILYMRINKRRKVPVTIMFRALGYSKQDILKLFYPIQHINIVDNKFLMSFNPNDYSSRLTYDLVDKNGKILLASGKRLSAKKAQNFIDEGLSEVEYPLEVLLDRYLAKPIVDPETGEILFDAMTRIDETKLKKLSEIGVKNFSIANDLAEGVDGSIINAFNADADSLKLLKQTEDIEDENHLSAIRIYKVMRPGEPVTKEAAKVFVNQLFFDPERYDLTKVGRMKMNHKLGLNIPEYITVLTHEDIIESVKYVIKVKNGQGHIDDRDHLGNRRIRSIGELLGNELHNGLIKMQKAIRDKLSTMSGPMNELMPHDLINSKMITSTIMEFFSGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKERAGFEVRDVHPTHYGRICPIETPEGQNIGLINTLATYSKVNEHGFIEAPYKVMKEGKVTDEIVYLTATQEEGKKIAAASNKLDKDGQFIDKMVVTRVDGEILHRPVTECNYADLSSHMVVGVAASLIPFLEHDDANRALMGANMQRQAVPLIKHEAPIVGTGVEKLVARDSWECVKARRSGIVEKVDGKHIYVMGDDDGEIYIDYYPLQKNLRTNQNTAFGQKPIVNIGQRVEIGQVIADGPNMDQGELALGVNAMVAFMPWNGYNFEDAIVISERLIRKDAFTSVHIYEKEVEARELKHGVEEITRDIPNVRDDELSHLDESGIIKIGTNVTGGMILVGKVSPKGEVKPTPEERLLRAIFGEKAGHVINKSLYCPPSMEGVVVDVKIFTKKGYDKDARTLELEKEERDYLEREHYDRLLMIDKEEMLRVTKLLTKEPLINDIKIGNTSYKAGDIINGEDLVEVNRFAMNAIIKSFSEEIQSEYNKTKNYFQKEKRLFRDEHEEKLNILEKDDILPNGVVKHVKIYIATKRQLKVGDKMAGRHGNKGIVSTIVPEVDMPYMEDGRGVDVCLNPLGVPSRMNIGQILEMHLGMAGRELGHQITKEFESKQKDFIKNLRAKMIEIADVAQMMNAAKTLGDMSDELLLHHARDWSRGVKFASPIFEGVNAVEFEKLFALAKMDTDGKTVLYNGLTGEKIKERVNVGYMYILKLHHLVDEKIHARSTGPYSLVTQQPVGGKALFGGQRFGEMEVWALEAYGASAVLKEMLTIKSDDVDGRVRAYKAITKGELVPESGIPETLFVLTKELQSLALDVEIFDEVEDNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: GCR_PAROL
Sequence: MDQGGLKRNCNRDDSLTFGETAVGVGSDTGDTAGSLLQPAAMHLPSPSSLPQLTVAPNGGAGTKDQGEFGGLFESPRGQCEGSEMKEGKIIRLQKRKHHLDIGMFNMEDNLSLLNQNISDLNRTSTSVISTSDTSVLGKLPLPNLFPQHIKQEGGFSLEKELGTYGGHTGGGPCDLDGNSGHLIEDTEIWQDLDLPNSLPEISDFELDSEVAHLDNILHDSSGGCGPDGSLLKETKVLVGNGGNCTDVNGTDQQHPLQHHQHQQQQHRHLLQHQQHQLHHQHQQPPSLLSSVMIKEEKDHDNSFIHIRTPGVVKQEKQENGSFCQSQCLQSSMSSLHGGGPMSSTMGAGAVPGYHYKASPSSTVGLQDQKPFGIFSNLPAVAESWTRGGRFGEPSGIQRGNDGLPSAAMSPFSVSFSSSSPRTGENSSSAVPGLSKPSGPTHKICLVCSDEASGCHYGVVTCGSCKVFFKRAVEGWRARQNTDGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLQAGMNLEARKNKKLIKMKVHRPTGSAEPISNMPVPVIPRMPQLVPTMLSVLKAIEPEIIYSGYDSTLPDTSTRLMTTLNRLGGQQVISAVKWAKSLPGFRNLHLDDQMTLLQCSWLFLMSFSLGWRSYEQCNGNMLCFAPDLVINKERMKLPFMTDQCEQMLKICNEFVRLQVSYDEYLCMKVLLLLSTVPKDGLKSQAVFDEIRMTYIKELGKAIVKREENASQNWQRFYQLTKLLDSMQEMVEGLLQICFYTFVNKTLSVEFPEMLAEIITNQIPKFKDGSVKPLLFHQK
What is the function of this protein?
Receptor for glucocorticoids (GC).  Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors.  Affects inflammatory responses, cellular proliferation and differentiation in target tissues.  Involved in chromatin remodeling.  Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay.  Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth.  Mediates glucocorticoid-induced apoptosis.  Promotes accurate chromosome segregation during mitosis.  May act as a tumor suppressor.  May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic gene expression.
What are the official names of this protein?
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=After ligand activation, translocates from the cytoplasm to the nucleus.
Protein: UBIA_PSEMY
Sequence: MYTRLLQSTTRLHPRAWDFIQLMRLDKPIGIYLLLWPTLWALWVAAEGVPSAKNLFIFVFGVILMRAAGCVINDYADRNFDGHVSRTRARPLASGKIQPREALVLFAVLVTASFVLVLFTNATTIWLSFGGLALAACYPFMKRYTFYPQVVLGAAFSWGMPMAFTAETGSLPPEAWLLYIANLLWTVAYDTYYAMADREDDLKIGVKSTAILFGDADRLIIASLQGLALLCLLLAGARFELGVWFHAGLLVAAACFVWEYHKTRNRKPMACFNAFLHNHWAGLAIFVGIVLDYALR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS19_DESRM
Sequence: MARSLKKGPFIDDHLLKKVDEMNEKGEKKVFKTWSRRSTIFPQMIGHTIAVYDGRKHIPVYITEDMVGHKLGEFAPTRTYRGHADKSERSTGLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.