PharMolix/UniProtQA huggingface dataset:
Protein: CAPSD_HBVG3
Sequence: MDRTTLPYGLFGLDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYRESLESSDHCSPHHTALRQAILCWGELMTLATWVGNNLEDPASRDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSASPASQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: TTDA_SHISS
Sequence: MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPGRSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNRLGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLLVHADLTFENLSHTRSAL
What are the official names of this protein?
L(+)-tartrate dehydratase subunit alpha, L-TTD alpha.
What is the protein family that this protein belongs to?
Belongs to the class-I fumarase family.
Protein: KAS1_STRHA
Sequence: MSRRVVVTGIGVVAPGGIGAARFWDLLAGGRTATRRISLFDPARLRSQIAAECDFDPSAHGLDDETVRRCDRYVQFALVATAEAVRDAGLDTTREDPWRMGAVLGTAVGGTTRLEHDYVLVSEGGSRWDVDHRRAEPHLHRAFAPSTLASTVAETFGAQGPVQTVSTGCTSGLDAVGYAYHAIAEGRADVCLAGASDSPISPITMACFDAIKATSPSNDDPEHASRPFDARRNGFVMGEGGAVLVLEELEHARARGADVYCELAGYATFGNAHHMTGLTREGLEMARAIDTALDMARLDGTDIDYVNAHGSGTQQNDRHETAAVKRSLGEHAYRTPMSSIKSMVGHSLGAIGSIEVVACVLALAHQVVPPTANYETPDPECDLDYVPREARERELRSVLSVGSGFGGFQSAVVLTGPERRLR
What is the function of this protein?
Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces halstedii.
What are the official names of this protein?
Putative polyketide beta-ketoacyl synthase 1, KS, Polyketide condensing enzyme.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
Protein: POL2_CNSV
Sequence: MFAPIGAPGMGERASQNFRSASGFRDLLVHAVKVLVLSAYQRRPCTSMLRPREQKRIKMRLKWMCLMKFCFMQNNYWDTQRRFTGGMHNVPELATFDAWLQHWRVVHWRLNIISEILIDFQALVRMMKNLAGQCHFDFYPVCTHCVQLVNNWYIAEFKPHLEEETEWWKDLVKPRMGNPVHEIEPNRKSQYVESRRIPPPLNGDEFANFLHVCQCAKLAFDVERAATEENFEDALDTLEEDFYDIDSTIPKRDLLAADARVVKRAFTLRRKRRPNRTSVYSMKGQPPVTFSASDLVSCLGQVLSTLPTVKMDREAIEDQQDHLEDKQGGEILTTPQFIEVLRKKKREVREKEFDDSTQGKLLPAEDFTLSKHDVFLANSVLDGLRKSKLIQRFAGKCATSTKITVDLTNKEEVVRYGPKELASEGFRQTFNVLNRPEYNALNKLAEAGWKEAKSVVLNLHIRSYLPQQMNAYAFCVIMWGHSSDAQEAALSGSYVYLGDGEATMLQLPLLCEYVGHNLQDFEAYKRSLVLSTVFPEFSGIADGKAMFGITSIEFTEYLPTSHAGITHERDSWDAMLRNHTEEKRRFLAGFNVVDTIEKGNRKGFSFPDFDLKAVPRHQAVVRTFEDQDVAPILSKAKSMRVKTFGSFRAGNIPVNFLGTPSNGQVASKHSVSENAGYSVGDMKSAENFVFTQLITVPAASTKGNVLAGVDILANARTTMSGFYMRWLQKGYIDTNLKLICHLPRAPFAGMSFFVLIDGTGYLAKDAPTSLNEEEILSYPLHLVTTSDVSSYEFVLDWHRYIGQVPFAEENAFLRPTLFLVACVSSTLALSAKVEFYLEAQSVGEELPRTLAPSPVLSYPFQNSFLEDLDLFLPPKRLTLGERETTIIPLSFAKSKKSGDAVLYSHAAARLAHFQGIGGVLHGVVYLVGSQLVASQSRISMWSKEQHIQHQAVNVHVDTDTGVAFDLPIKDAFYASSVYGDSGAVIQVTCLCSPMSPNAIKAPFDMIFKIRGFTPDAPMCRTINFTQRFGWFAVEPTTSTGAIKLKIWPVSNHLESEDMKVTGYTNAFLQMCQTSTMHFGSVIIHFSWTLFGGTTNAATAGGVVTIAEGFGPEEENFRGHCRNLSIYEGRATVPLELGTFAGPTPLKKLDFKYRNWIRFTTPKGRNISSIFCAIEVLPGFSFYGRTGSPRLSVVGTTVPPTADASTSNSQGGDEDIGDQYSAALGRGRGRGSRPGPSPIRG
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
RNA2 polyprotein, P2.
What is the protein family that this protein belongs to?
Belongs to the nepoviruses RNA2 polyprotein family.
What are the subcellular locations of this protein?
[Movement protein]: Host cell junction, host plasmodesma. Note=Assembles in tubules that are embedded within modified plasmodesmata. SUBCELLULAR LOCATION: [Coat protein]: Virion.
Protein: RS3_SYNC1
Sequence: MGQKVHPIGFRLGVVKTWSSRWYAEGEYSQLLHEDIKLRNYLKKRLYHAGVAKIELERAASKAKINVYAARPGIIIGKKGAEVEALKKDLARLTDKEVFINIQEVRKPEIDAQLVAENVATQLERRVAFRRAMKKSVSMALKFGAQGIKITCSGRLGGAEMSRTEWYREGRVPLHTLRADIDYGFAEAKTTYGIIGVKVLIFKGEVLSQD
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TATB_YERPE
Sequence: MFDIGFSELLLVLVIGLVVLGPERLPVAVRTVSGWIRTLRSLAATVQNELAQELKLQELQDSLKKVEQAGLQNLTPELKASMDELKEAAEALKRSYHVDAGSEAPHTIHNPLVTEPEAIHDGVTPAEPATQVSALAQAPNILEAGTASVVDSVVEAAPVTTVKSVVQGEVLVKSTPVQEVGLADVMDKPVTKQQIDTIDSHGTDLSSAGPSRIHQPGGDQ
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YKZU_BACSU
Sequence: MATYNAIIYSGGYSQTLRDFAGWTGDLLTTIQDMKLHAQEFNSPYDAAMKIIGNMYQFSLDDLFSDVDAINLANKTSVGANAQPLNIAIRDYYSNNDCMNRFTQFVNNRFDGSLDKIFSEAEYYLNTNLDPVVVPIRLAFKRAFDVEDYSEEIGKITAQAFRDVIEKKMISE
What are the official names of this protein?
Uncharacterized protein YkzU.
Protein: M313A_XENLA
Sequence: MHLNDTMASPLEPLSWSSSPNLIVDTLREDKDYRVNYGDCTTIGHHEIKETPDKCDSLDNANSPVTATVLTSISEDSRDQFENSVLQLRDQDEPENTAPQGSSHSGDGGSYSGNEDIRIHFGHSGSGNSGFLEGLFGCLRPVWNIIGKAYSTDYKLQQQETWEVPFEEISELQWLGSGAQGAVFLGKFRGEEVAIKKVREQKETDIKHLRKLKHPNIIAFKGVCTQAPCYCLIMEYCAHGQLYEVLRAGRKVSPRLLVDWSNGIASGMNYLHLHKIIHRDLKSPNVLVTHTDTVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVLLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWHSKPRNRPSFRQILMHLDIASADVLGTPQETYFKSQAEWREEVKKHFEKIKSEGTCIHRLDEELIRRRREELRHALDIREHYERKLERANNLYMELSAIMLQLEVREKELIRREQAVEKKYPGTYKRHPVRPIVHPNSVEKLIKKKGPPSRIPSQTKRPDLLKSDGIVSAEGSAASASPISGSPKTSSGGGKNRYRSKPRHRRVNSKGSHADFIGVLKHLESPALSQQSSQHQTLASPPVTSCSPYHETSQVMPTFHQTLNVHGQNIANCANNLRYFGPAAALRSPLSSHAQRRMSGSSPDLLSSTLEADSHIQPEREYEYCQQDPYNRCPGCTEAVQQDTDTGNWDSTNVVTAEYRTSGGDPPESPRHNLVQENNEKLESGGEQFSSFKAAIGVSALTVPTPPALPRRIRTLRKNGDESSEEEEGEVDSEVEFPRRHRPPRGMSKCQSYSTFSSENFSVSDGEEGNTSDHSNSPDDVAGGGKVWHGDKLDDLSQTPEIPIEISMQSDGLSDKECAVRRVKTQMSLGKLCTEEHNYENAGNFAESDCDSSEGECSDATVLTNNPVNSSTW
What is the function of this protein?
May have a role in the JNK signaling pathway.
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 13-A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: Y476_PSE14
Sequence: MKKVSPSYLKHQFLIAMPHMHDENFAQTLTYVVEHNANGAMGLVINRPQSLTLADVLEQLRPELPAPKRCQEIAIHSGGPVQTDRGFVLHPSGQTFQATVNLPGGISLSTSQDVLFSIADGYGPDQNVITLGYAGWDAGQLDAEMADNAWLTCSFDPAILFDVDSEQRLDAAARRLGINLNLISTQAGHA
What are the official names of this protein?
UPF0301 protein PSPPH_0476.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: GLPK_KLEP7
Sequence: MTDKKYIVALDQGTTSSRAVVMDHDANIVSVSQREFEQIYPKPGWVEHDPMEIWASQSSTLVEALAKADINSDQIAAIGITNQRETVVVWERETGKPIYNAIVWQCRRTAEICEQLKRDGMEEYIRKATGLVVDPYFSGTKVKWILDHVEGSRERAKRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHDLDWDDKMLDALDIPRAMLPEVRKSSEVYGQTNIGGKGGTRIPIAGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVTSTHGLLTTIACGPRGEVNYALEGAVFMAGASIQWLRDEMKLISDAFDSEYFATKVKDTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNSNHIIRATLESIAFQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYSGWKKAVKRALAWEEHDEA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: PRMA_SHESH
Sequence: MPWIQLKIDTDNQHADALSDLLMEEGSLSITLEDGKDTPIYEPTLGETPLWNHTVLTALFEADRDLAIVVEQLKLQPYLGEDFSYKIEQVEDKDWEREWMDNFHPIKFGERLWICPSWREIPDPDAVNIILDPGLAFGTGTHPTTALCLEWLDSLDFADKEVIDFGCGSGILAVAALKLGATKVTGIDIDYQAIDASKANAERNGVEDQLALFLPEDQPKDLQADILVANILAGPLRELAPLIAEKVKTGGQLALSGLLKEQAEEVAEFYTQWFDMDEPAHKEDWSRLTGIRK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA_STRP1
Sequence: MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKDGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_PYRAR
Sequence: MLFERARQVFPGGVNSPARALKHLPSSLVARAASGPYLYTDRGRLVDYCMAFGAIILGHAHPRVKRAVEEQLERGWIYALLTEQEVEFAEAIRRHMPSVEKMRIVNTGTEATMNAIRLARGYTKRDVIIKFDGNFHGSHDYVLVKAGSGAATWGIPTSAGVPQDVVKLTVVAPYNDVDAFLKAVKEVGDRLAAVIAEPVAGNYGLIIPDAEFLKALREETKRVGALLIFDEVITGFRLGLGGAQGRFGIRPDLTTLGKAVGGGFPIGIFGGRAEVMDLVAPSGPVYNAGTYNAHPVSVTAGLAVLKELETGEPFRTADEAAERLAKGIEDIAGRLGFDVVVKKIASMFQFYFKKGDVKTPQDVRESNEKMYLKLHEIALRHGVYLTPSQFEVNFTSAAHTREVVEETLAALEKAFQQLKTEIG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_SORC5
Sequence: MPKMKTNRAAAKRFKVTGSGRIRRSKGGLNHCMQEKSKKRLRRLRKNDMVDSAMEKRVKLLLPYG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CLPX_SALHS
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: VATD_PYRFU
Sequence: MPEILKVKPTRMELLKLKRRVKLAERGHKLLKEKQDALIMEFFTIYDEALSMRRELIKKIGEAFEALRLAQVEVGSVRLKEIAIGVNPNKEIEVRSRNIMGVRVPLIEVPELKRKPSERGYAFISTSSAVDVAAEKFEEVLELAIRLAEVEESLKRLGKEIEKTKRRVNALEYIIIPRMKNTIKFIEQHLDEMERENFFRLKRIKALLEARESM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: UTP6_HUMAN
Sequence: MAEIIQERIEDRLPELEQLERIGLFSHAEIKAIIKKASDLEYKIQRRTLFKEDFINYVQYEINLLELIQRRRTRIGYSFKKDEIENSIVHRVQGVFQRASAKWKDDVQLWLSYVAFCKKWATKTRLSKVFSAMLAIHSNKPALWIMAAKWEMEDRLSSESARQLFLRALRFHPECPKLYKEYFRMELMHAEKLRKEKEEFEKASMDVENPDYSEEILKGELAWIIYKNSVSIIKGAEFHVSLLSIAQLFDFAKDLQKEIYDDLQALHTDDPLTWDYVARRELEIESQTEEQPTTKQAKAVEVGRKEERCCAVYEEAVKTLPTEAMWKCYITFCLERFTKKSNSGFLRGKRLERTMTVFRKAHELKLLSECQYKQLSVSLLCYNFLREALEVAVAGTELFRDSGTMWQLKLQVLIESKSPDIAMLFEEAFVHLKPQVCLPLWISWAEWSEGAKSQEDTEAVFKKALLAVIGADSVTLKNKYLDWAYRSGGYKKARAVFKSLQESRPFSVDFFRKMIQFEKEQESCNMANIREYYERALREFGSADSDLWMDYMKEELNHPLGRPENCGQIYWRAMKMLQGESAEAFVAKHAMHQTGHL
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 6 homolog, Hepatocellular carcinoma-associated antigen 66, Multiple hat domains protein.
What is the protein family that this protein belongs to?
Belongs to the UTP6 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: KAD_METMA
Sequence: MNIILFGPPGAGKGTQAKKLVDFYGIPQISTGDILRANVREGTELGLAAKAYMDKGELVPDNVLIGIIKNRLNEEDCKKGFILDGYPRTVPQADALETILDEIDKPIDVVLNLEVPDEVLVERISGRLMCKCGASYHTIANPPKKDNICDICGGEVYQRDDDKAEAVQNRLDVYKKQTQPLINYYEEKGILVTLDGTKDINVVFEDIKAVLAKFA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIAO1_DEBHA
Sequence: MVKLIKSIKAHNDKAWCAKSHPTLPLLATASTDRTSHIYNLSAKKNFPLLAKLEEAHKRSVRSVDFKPPLGGVESPVDDFLDLPALATGSFDSTISIWGIDEPEEQDSMDDGDDDDDDEKINDKHAQLLTSINNEWNLMAIIEGHENEVKSVAWNYQGNLLASCSRDKTIWIWETDPETLEEFECISVLSDHQHDVKHITWHPSQNLLASSSYDDTIKLYKQDEDDDDWSCVGILNGHGGTVWCSSFENPTSPTFDANKIRLVSASDDLSVRIWSSIVEQTEQIEDTTDRLPSSIKSTNNEMVWEEEAILPAIHKYAVYSVSWSAKTGKISSTGSDGKLVIYRETESKKWEIESVYESAHGVYEINSVSWCTLDDKTEVLVTAGDDGAINIWEP
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Preferentially localized to the nucleus.
Protein: NDHK_SYNPW
Sequence: MAGESPSIQALRDLREASCGPVAGAADGAPTVTQDLSENVILTSLDDLHNWARLSSLWPLLYGTACCFIEFAALLGSRFDFDRFGLVPRSSPRQADLLIVAGTVTMKMAPALVRLYEQMPEPKYVIAMGACTITGGMFSADSTTAVRGVDKLIPVDLYMPGCPPRPEAIFDAVIKLRKKVANESVADRRQLQQTHRYCTVAHAMTAVEPIVTGAYLRAETQVAALQPGAGLPMPALETADAVQPSEPS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, NAD(P)H dehydrogenase I subunit K, NDH-1 subunit K, NDH-K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LFTR_ECOHS
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMO_ECOLI
Sequence: MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGMSLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAEMAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNVRWRVTDAGFEVFALEPR
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Thr)(GGU) that read codons starting with adenosine (PubMed:9537379, PubMed:25063302).  The methyl group of m(6)t(6)A37 appears to slightly improve the efficiency of the tRNA decoding ability (PubMed:9537379, PubMed:25063302).
What are the official names of this protein?
tRNA (adenine(37)-N6)-methyltransferase, tRNA (m6t6A37) methyltransferase, tRNA methyltransferase O.
What is the protein family that this protein belongs to?
Belongs to the tRNA methyltransferase O family.
Protein: SYV_NOCFA
Sequence: MTSTAPDNSRNRADALPKSWDPSAVEAEMYERWVSAGYFTADPASGKPAYSIVLPPPNVTGTLHMGHALDHTLMDTLARRKRMQGYEVLWLPGMDHAGIATQTVVEKQLAVDGKTKEDFGRELFVEKVWDWKRESGGAIQWQMRALGDGVDWSRDRFTMDEGLSRAVQTMFKRLYDAGLIYRAERLVNWSPELRTAISDIEVKHEDVEGELVSLRYGSLNDDEPHVVVATTRVETMLGDTAVAVHPDDPRYRDLIGTTLEHPITGRQIPIVADDYVDPEFGSGAVKITPAHDPNDFEIGLRHNLPMPTIMDERGRIANTGTEFDGMDRFEARVKVRERLAREGRVVAEKRPYIHSVGHSERTGEPIEPRLSMQWWVKVEALAKAAGDAVRNGQVVIHPASQEPRWFEWVDNMHDWTISRQLWWGHRIPIWYGPDGEVVCLGPGETPPEGWVQDPDVLDTWFSSGLWPFSTMGWPDATPELTKFYPTSVLVTGYDILFFWVARMMMFGMYVAEDPALTAGKDPGQVQVPFKDIFLHGLIRDQHGKKMSKSRGNGIDPLDWIRSYGADALRFTLARGAQPGGDLSVGEPHALASRSFVTKLFNATKFALLNGAAPGELPDRGSLTDADRWILDRLDEVLAEVDAAFDAYEFGKACEALYHFAWDELCDWYLELAKVQFAADGARAESTRTVLGTVLDAVLRLLHPVIPFVTESLWKALTGGESVVVAAWPTASGVTPDADAARRIADAQRLITEIRRFRSDQGLADKQKVSAKLIGVDSAELDALAPAIAALARLTEAGPDFAATASVEVRLSGATVTVELDTSGSVDLEAERKRLEKDLAAAQKELATTEGKLGNEAFLAKAPEQVVDKIRTRRDVAAAEVARIGARLAELGAR
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB1F2_I83A5
Sequence: MEREQDTPWTQSTEHTNIQKEENGQQTQKLERPNSTQSMDHYLKIMNQVDMHKQTAFWKQWLSLKNPTQESLKTRVLKRWKLFNKQGWTS
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.