PharMolix/UniProtQA huggingface dataset:
Protein: Y0569_MYCTU
Sequence: MKAKVGDWLVIKGATIDQPDHRGLIIEVRSSDGSPPYVVRWLETDHVATVIPGPDAVVVTAEEQNAADERAQHRFGAVQSAILHARGT
What are the official names of this protein?
Uncharacterized protein Rv0569.
Protein: UPP_CLOBJ
Sequence: MSKVTQIAHPLILHKLALIRDKNTGSKDFRELVEEVAMLMAYEVTRDLQLKEVEIETPICKTKCKMLSGKKVAIVPILRAGLGMVGGMTSLIPAAKVGHIGLYRDEETLKPVEYFCKLPQDIGDRDVIVTDPMLATGGSAKDAITLLKQKGAKHIRLMCLVAAPEGIKEVMDEHPDVDIYVASVDEKLNEKGYVVPGLGDAGDRLYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ZN326_BOVIN
Sequence: MDFEDDYTHSACRNTYQSFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMSDFGSIHRPGIVVDYQNKPTNVTVAAARGIKRKMIQPFNKPGGTFIKKPKLAKPVEKMSLSKSPTKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESASHQETLDHIQKQTKFDKVVMEFLHECMVNKFKKTSIRKQQTNNQTEAVKIIEKDVMEGVTADDHMMKVETVHCSACSVYIPALHSSVQQHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFIKGENPFEIQDHSQDQQIEGDEEEEEKIDEPVEEEEEEEEEEEEVGEVEEAEEVGEGGGVEGVGDTEEGGDVEGEGEVGAVGEGEGEGEGVGEVEEEEAKEEPVGFSVDQAEEN
What is the function of this protein?
Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions.  May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro (By similarity).
What are the official names of this protein?
DBIRD complex subunit ZNF326, Zinc finger protein 326, Zinc finger protein interacting with mRNPs.
What is the protein family that this protein belongs to?
Belongs to the AKAP95 family.
What are the subcellular locations of this protein?
Nucleus matrix.
Protein: RSMJ_SALPB
Sequence: MQICLMDETGATDGALSVLAARWGLEHDEDNPMALVLTPQYLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLTRGYADADIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHRQKSALVKKEMRVFQSLVGPDLDADGLLEPARQLATKRVVVKRPDYAPPLADVATPNAIVTKGHRFDIYAGTPLTE
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_DEHMB
Sequence: MLNKRVIPCLDVNNGRVVKGTSFVNLRDAGDPVELAARYYREGADELVFLDISATTEERKTMAEVVEKVSKEVFIPLCVGGGLRSIADMTTLLRAGADKVSVNSAAVSDPDLISRGAEKFGRQCIVVAIDAKREGNSWQVYTHSGKKPTGLDAVEWAMKAEQLGAGEILLTSIDADGKNTGYDNELNREVSSRLNIPVIASGGAGSPEDLYNALDKGQADAVLAASIFHYGRYSIAEVKKYLKSKGLPVRLEN
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRF_NEIMF
Sequence: MEIILGIVMFTVIVLVLALMILFAKSKLVSEGDITIKVNGEKELTMPAGGKLLGALANEGIFIPSACGGGGSCGQCRVVVKSGGGDILPTELSHISKREAREGCRLSCQVNVKTDMDIEVPEEVFGVKKWECTVISNDNKATFIKELKLAIPEGEEVPFRAGGYIQIEAPPHTVAYKDFDIPEEYHEDWDKYNLWQYVSKVDEPILRAYSMASYPEEKGIIMLNVRIATPPPRVPDAPPGQMSSYIWSLKPGDKVTISGPFGEFFAKDTDAEMVFIGGGAGMAPMRSHIFDQLKRLNSKRKITFWYGARSKREMFYVEDFDQLAAEFPNFTWHVALSDPLPEDNWDGYTGFIHNVVYENHLKNHEAPEDCEFYMCGPPIMNQSVIKMLKDLGVEDENILLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ACTP_ECOLU
Sequence: MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRNDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDE6C_HUMAN
Sequence: MGEINQVAVEKYLEENPQFAKEYFDRKLRVEVLGEIFKNSQVPVQSSMSFSELTQVEESALCLELLWTVQEEGGTPEQGVHRALQRLAHLLQADRCSMFLCRSRNGIPEVASRLLDVTPTSKFEDNLVGPDKEVVFPLDIGIVGWAAHTKKTHNVPDVKKNSHFSDFMDKQTGYVTKNLLATPIVVGKEVLAVIMAVNKVNASEFSKQDEEVFSKYLNFVSIILRLHHTSYMYNIESRRSQILMWSANKVFEELTDVERQFHKALYTVRSYLNCERYSIGLLDMTKEKEFYDEWPIKLGEVEPYKGPKTPDGREVNFYKIIDYILHGKEEIKVIPTPPADHWTLISGLPTYVAENGFICNMMNAPADEYFTFQKGPVDETGWVIKNVLSLPIVNKKEDIVGVATFYNRKDGKPFDEHDEYITETLTQFLGWSLLNTDTYDKMNKLENRKDIAQEMLMNQTKATPEEIKSILKFQEKLNVDVIDDCEEKQLVAILKEDLPDPRSAELYEFRFSDFPLTEHGLIKCGIRLFFEINVVEKFKVPVEVLTRWMYTVRKGYRAVTYHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLYQMKSTSPLARLHGSSILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLFEVAIIATDLALYFKKRTMFQKIVDACEQMQTEEEAIKYVTVDPTKKEIIMAMMMTACDLSAITKPWEVQSQVALMVANEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVCTFVYKEFSRFHKEITPMLSGLQNNRVEWKSLADEYDAKMKVIEEEAKKQEGGAEKAAEDSGGGDDKKSKTCLML
What is the function of this protein?
As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP.
What are the official names of this protein?
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', cGMP phosphodiesterase 6C.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: KPYK_STAA3
Sequence: MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PEP-utilizing enzyme family.
Protein: ZNUB_HAEIN
Sequence: MFEILFPALLTGIVLSLITAPLGVFVVWRKMAYFGDTLSHSALLGVALGIFLQVNPYIAIVVLTLILAIAMVWLESNTQFSIDTLLGIIAHSCLSLGVVTVGLLRNVRVDLMNYLFGDLLAINYTDLIYIGIGVIIVLSTLIYFWQSLLSTTVSPELAQVEGINIKKMRFILMILTALTIALSMKFVGALIITSLLIIPAATARRFARTPESMVGWAIIMSMLSIIGGLILSAFYDTAAGPSVVICSAFLFVLSLFKRERL
What is the function of this protein?
Involved in the high-affinity zinc uptake transport system.
What are the official names of this protein?
High-affinity zinc uptake system membrane protein ZnuB.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNZ_CYAP4
Sequence: MQITFLGTSSGVPTRSRNVSSVALRLPQRAEVWLFDCGEATQHQILRSDVRLSQIRRIFITHMHGDHIFGLMGLLASCGLAGNVSRMDIYGPPGLNKYLEACQRYSQTHFSYPIRVHTVQPGVIYEDEEFTVSCTALHHRVTAFGYRVSEKDRPGRFDVQQAVALGIPSGPLYGQLKRGEQVTLADGRVIHGQQLCAPPELGRKLAYCTDTIYCEGAVELAQDVDVLIHEATFAHQDADMAYQRLHSTSTMAAQVALAAAAKRLFLTHFSPRYAPGNDLQIDNLLEEARAIFAPTELAYDFLTYELPRHLEPERQTLSVG
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: SULA_SHIB3
Sequence: MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: CHBG_ECOSE
Sequence: MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAIDHAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEEGIALRIDRQPLSNSGDLPANLRSSQGFSSAFYGEEISEALFLQVLDDASHRGDLSLEVMCHPAFIDNTIRQSAYCFPRLTELEVLTSASLKYAIAERGYRLGSYLNV
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FX4L1_HUMAN
Sequence: MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEASQKFLEQSLQPGLQVARWGGVALPREHIEGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAPALPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQPSLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPSSLSDNFAATAAASGGGLRQRLRSHQGRGAGRAPVGRVGAAAVSGGGRGL
What are the official names of this protein?
Forkhead box protein D4-like 1, FOXD4-like 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ILVC_TRIEI
Sequence: MARMYYDSDANLDILNDKTIAIIGYGSQGHAHALNLKDSGSKVIVGLYSGSKSATKAKDAGLDVYPVDEAAEKADLIMILLPDEVQKTVYKNQIEPHLKEGKILAFAHGFNIHFGQIIPPENVDVVMVAPKGPGHLVRRTYEQGEGVPCLFAIFQDASGQGRDRAMAYAKGIGGTRAGILETTFREETETDLFGEQVVLCGGLSALIKAGFETLVKAGYQPELAYFECLHEVKLIVDLVVEGGLANMRDSISNTAEFGDYTRGPRIVTDETRAQMQKILSEIQSGQFAREFVMENQTGKPVFTAMRRQEAEHSIEEVGKDLRAMFSWLKKR
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MATP_SALDC
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYVEASAAQEAVNLLLALENEPVRVNVWIDRHMNPALLNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFMVWQRLAGLAQRRGKTLSETIVQLIEDAEHKEKYATQMTTLKQDLQALLGKK
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABP1_FASGI
Sequence: MADFVGSWKYGDSENMEAYLKKLGISSDMVDKILNAKPEFTFTLEGNQMTIKMVSSLKTKITTFTFGEEFKEETADGKTAMTTVTKDSESKMTQVTTGPEYTTHVVREVVGDKMIATWTVGDVKAVTTLLKA
What are the official names of this protein?
Fatty acid-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein: RBM25_ARATH
Sequence: MADESSSPATGDPNSQKPESTTPISIPNPNPNPSLTPPPPQQHSQPPVAPLVPPGPPYAPPAQIPSSLLPTNLPPPPPFRPGMQFTPVANFQNPSSGVPPPGSMPQYQPQPGMRPFQPMANGYPGIHGVAPPGAMPPHGLLRYPSPYPTMVRPGFIMRPPGTIGAVQLAPRPLIPGMPGLRPVMPPMVRPASLPFVTPAEKPQTTIYIGKIATVENDFMMSILEFCGHVKSCLRAEDPTTKKPKGFGFYEFESAEGILRAIRLLTQRTIDGQELLVNVNQATKEYLLKYVEKKIETAKKAKESQGTKENQAEGPESEQDKLESADNETGKDGESKIKENIDIANSAVLTDEEREADREAMEKIETAIEERLKSNPLPPPPPPPADGSGMEFAFKSKDGDSNTDVARSDAAANDVETSGEHNRPDTSSPDWSKRNDRRSRERGEKEQEMDRYEREAERERSRKEREQRRKLEDAERAYQTRLRQWERREREKEKERQYEKEKEKEKERKRKKEIRYEEEEEEDDDDSRRRWHRAALDERRRRQLREKEDDLADRLKEEEEVAEAKRSAEEQNLQQQQLDALRILSGQAAIGSETVQTSPIENDHKATLQTVGESANEHHAADFEENGSGNESMAIDNNSGSEAHAPSKKLGFGLVGSGKRTSVPSVFYEEDEDEARKAKKMKPLVPIDYSTEEQEAVAHGGSGNTPPHLALAAEFAKRISSTNPKEETIETEKQRSRRSHDKASHRDRERERERDRDRDRVRDRGDGHSGPTKDAKESGKAKIIDTKFLDAKQLIDTIPKTKEDLFSYEINWAMYDKHQVHERMRPWISKKIMEFLGEEEATLVDFIVSNTQQHVQASQMLELLQSILDEEAEMFVLKMWRMLIFEIKRVEAGVPVKSKA
What is the function of this protein?
RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing (PubMed:26404089, PubMed:28971960).  Negative regulator of responses to abscisic acid (ABA), including in early development (PubMed:26404089).
What are the official names of this protein?
RNA-binding motif protein 25.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURC_SYNR3
Sequence: MSQPLSLTAEQPVHFIGVGGIGMSAIAGILAERSYNVTGSDPKQSAQSQLLRQQGARVFQQQNAATIDAICSGVDRAPLVVVSSAIPETNPELEAARGAGLRVVHRSELLAWLINAQHSIAVAGSHGKTTTSSLIASLLHSAGLDPTAIIGGVVPAFGSNARNGAGEWLVAEADESDGSLVRFHPQLGLITNLELDHTDHYPNLDALVATMRRFSGNCSSVLANRDCPVLSAELSADHWWSLQENSSAHFRAVPLSLDGAGCRADYLEDGRRLGELALPMAGIHNLSNALAAVAACRLAGASFADLQAALTELVPPGRRFDLRGEWQGRLIVDDYAHHPSEVDATLTMAQLMVSSGKSTLPWVPKRVVAVFQPHRYSRTAQFMERFAEALGCADEVLVAPLYSAGESAIEGVSSATLAEKVQQAGHSARALADMDSLVDAVQQCSSAGDLVLVMGAGDVNQLWSRLQSSADQQGLATAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPAC2_HUMAN
Sequence: MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIMKNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKDYKDQKASRNESTF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.
What are the official names of this protein?
DNA-directed RNA polymerases I and III subunit RPAC2, RNA polymerases I and III subunit AC2, AC19, DNA-directed RNA polymerase I subunit D, RNA polymerase I 16 kDa subunit, RPA16, RPC16, hRPA19.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FTCD_HUMAN
Sequence: MSQLVECVPNFSEGKNQEVIDAISGAITQTPGCVLLDVDAGPSTNRTVYTFVGPPECVVEGALNAARVASRLIDMSRHQGEHPRMGALDVCPFIPVRGVSVDECVLCAQAFGQRLAEELDVPVYLYGEAARMDSRRTLPAIRAGEYEALPKKLQQADWAPDFGPSSFVPSWGATATGARKFLIAFNINLLGTKEQAHRIALNLREQGRGKDQPGRLKKVQGIGWYLDEKNLAQVSTNLLDFEVTALHTVYEETCREAQELSLPVVGSQLVGLVPLKALLDAAAFYCEKENLFILEEEQRIRLVVSRLGLDSLCPFSPKERIIEYLVPERGPERGLGSKSLRAFVGEVGARSAAPGGGSVAAAAAAMGAALGSMVGLMTYGRRQFQSLDTTMRRLIPPFREASAKLTTLVDADAEAFTAYLEAMRLPKNTPEEKDRRTAALQEGLRRAVSVPLTLAETVASLWPALQELARCGNLACRSDLQVAAKALEMGVFGAYFNVLINLRDITDEAFKDQIHHRVSSLLQEAKTQAALVLDCLETRQE
What is the function of this protein?
Binds and promotes bundling of vimentin filaments originating from the Golgi.
What are the official names of this protein?
Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, FTCD, LCHC1.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the formiminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=More abundantly located around the mother centriole.
Protein: RFAC_SALTY
Sequence: MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIQFDWAVEEGFAQIPSWHSAVDRVIPVAIRRWRKAWFSAPIKAERTAFRRAVCANQYDAVIDAQGLVKSAALVTRLAHGIKHGMDWSTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYDKPQSQGDYAIAKHFLHCQQAVSDPYAVFLHATTRDDKHWPEANWRELIGLVGNTGLRIKLPWGAPHEEARAKRLAEGFDYVDVLPRMSLEEVARVLAGAKFVVSVDTGLSHLTAALDRPNITLYGPTDPGLIGGYGKNQMACCSPEQNLANLDATSVFGKIH
What is the function of this protein?
Heptose transfer to the lipopolysaccharide core.  It transfers the innermost heptose to [4'-P](3-deoxy-D-manno-octulosonic acid)2-IVA.
What are the official names of this protein?
Lipopolysaccharide heptosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 9 family.
Protein: HTPG_NITEC
Sequence: MQTAENVEHLNFQAEAKQLLRLMIHSLYSNKEIFLRELISNASDAADKLRFEGLSDTALYESDPDLKIRIAYDKEARTITISDNGIGMSRQEVIDNIGTIAKSGTREFIDSLTGDQARDANLIGQFGVGFYSAFIVADKVTLTTRRAGLTTEHGVRWESSGEGEYTLETVEKRDRGTEVVLHLREDEDELLSSFQLRSIIRKYSDHITLPIIMKKEVWDDESKAYKISDEEETVNQASAIWARPKNEITQEQYDEFYKHVAHDFEPPLAHVHARVEGKQEYIQLLYIPAHAPFDLFDREHRHGLKLYIKRVFIMDDAEKLLPGYLRFVRGIIDSNDLPLNVSREILQESKDIDSIRAGSVKKVLGLIEDLATSDKSEDQEKFKIFWREFGQVLKEGVAEDYSNRERIAKLLRFTSTHDEQEEQTVSLDDYIARMKPEQEKIYYITADGLKAAQSSPHLEIFRKKGIEVLLLHDRIDEWLTANLNEYAGKSLQSIAKGDLDLGKLEDEVEKQEHEKEAGDFQELTAKMKEVLGELVKDVRITYRLTESPACLVADTHDMSGNLGRLLKSAGQKVPDSKPFLEINPHHPMVQRLKYEEAKFADWSHILFDQALLAEGGQLEDPASFVRRLNDLLLQNILSGK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2690_PELTS
Sequence: MILTTTPNIEGKPVLEYLGIVTGEAIMGANIVRDFFAAVTDIVGGRSGAYEQKLSHARQIALNEMAEEARRLGANAVVGIDIDYEVVRDGMLMVTASGTAVKI
What are the official names of this protein?
UPF0145 protein PTH_2690.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RRP8_CAEBR
Sequence: MGKKRINEVSTTEGAPAEKKKKVEKWLNTSSEDGEGTKKKKRPWRNKVRKLAAKKAAAERRVENSEESTILEPVATAEEATKKKKKRGPKKKKYKPEAAEVEKKNEEGDTVKENPIAEAKKRLDAGRFRMLNEKLYTCTGSEAFDFFKEDRTAFDLYHRGFADQVKKWPNHPLREIIRWLQAKPDKQAVFDLGCGEAKIAEAVGEKHTIRSFDLVAVNDRVESCDMSKLPAEDGSADVVIFCLSLMGTNLYDFIKEARRVLRTGGVLKIGEVTSRFVSIKQFCEAINKMGFETTNRRQLTDYFMMFDFRKIDKVEQKRPYGLKLKPCLYKKR
What is the function of this protein?
Probable methyltransferase required to silence rDNA.
What are the official names of this protein?
Ribosomal RNA-processing protein 8.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RRP8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RADA_STRP3
Sequence: MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIENIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDISQGIEVVGVTTVGQVLKAVFS
What is the function of this protein?
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks.  Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster.  Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB.  Does not have RecA's homology-searching function.
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: PLPP4_HUMAN
Sequence: MRELAIEIGVRALLFGVFVFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEERPTADSAPSLPLEGITEGPV
What is the function of this protein?
Magnesium-independent phospholipid phosphatase with broad substrate specificity (PubMed:17590538).  Preferentially catalyzes the conversion of diacylglycerol pyrophosphate into phosphatidate but can also act on phosphatidate and lysophosphatidate (PubMed:17590538).  Phospholipid phosphatases are involved in both the synthesis of lipids and the degradation or generation of lipid-signaling molecules like diacylglycerol (PubMed:28851360).
What are the official names of this protein?
Phospholipid phosphatase 4, Phosphatidic acid phosphatase type 2 domain-containing protein 1A.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.