PharMolix/UniProtQA huggingface dataset:
Protein: PSUG_DINSH
Sequence: MTHLPSFVDVHADVRNALETNAPVVALESTIITHGMPFPDNVEMAKAVEEEIRARGAIPATIAVLDGVLKIGLGADELEALAKVKDALKISRADIGYAISQGKSAGTTVAATMIVAQMAGIRVFATGGIGGVHKGVETSFDISADLTELGRTDVIVVAAGAKAILDVPKTLEVLETQGVSVVGYRTDTLPAFWTSGSDLDIPLRLDSAAEISEFQKVRDALRLGGGMLVANPIPAGDEIPAEIINGYIATAQAEMAAQSISGKAVTPFLLQRIFELSEGRSLRSNIALVKNNARLAADIAVALHS
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: TSAD_STAEQ
Sequence: MTNNKLILAIETSCDETSVSVIKNGTELLSNTVLSQIDSHKRFGGVVPEVASRHHVEGITATIDESLVSAKVKMEDIDAIAVTQGPGLIGALLIGINAAKALAFAYDKPIIPVHHIAGHIYANHLEQPLTFPLMSLIVSGGHTELVYMKNHLDFEVIGETRDDAVGEAYDKVARTINLPYPGGPHIDRLAAKGKDVYDFPRVWLEKDSYDFSFSGLKSAVINKLHNLRQKNIEIVAEDVATSFQNSVVEVLTYKAIHACKTYNVNRLIVAGGVASNKGLRNALSEACKKEGIHLTIPSPVLCTDNAAMIGAAGYYLYQAGLRGDLALNGQNNIDIETFSV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MECA_LISMO
Sequence: MEIERINEDTIKFYISYLDLEERGFNQEDVWYDREKSEELFWDMMDELKYEEEFSPEGPLWIQVQALKHGLEVFVTKATIGGKGEDGFDVTLSSPDELAEEKIEKLLEENFNPVKKEALGEDDTLEFILEFRDFEDAISLSRATGLENLVTKLYSYQGKYYLNVEFPENKYDESNIDNAVSILLEYGLESNLTGYMLAEYGKVIFDVPALKQIRKHF
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: PHZG_PSEFL
Sequence: MNGSIQGKPLLGKGMSESLTGTLDAPFPEYQTLPADPMSVLHNWLERARRVGIREPRALALATADSQGRPSTRIVVISEISDAGVVFSTHAGSQKGRELLHNPWASGVLYWRETSQQIILNGQAVRLPNAKADDAWLKRPYATHPMSSVSRQSEELQDVQAMRNAARQLAELQGPLPRPEGYCVFELRLESLEFWGNGQERLHERLRYDRSDTGWNVRRLQP
What is the function of this protein?
Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control (PubMed:9573209, PubMed:23897464).  Catalyzes several oxidations in the terminal steps of core phenazine biosynthesis.  It oxidizes both hexahydrophenazine-1,6-dicarboxylic acid (HHPDC) and tetrahydrophenazine-1-carboxylic acid (THPCA) and thereby contributes to the generation of both phenazine-1,6-dicarboxylic acid (PDC) and phenazine-1-carboxylic acid (PCA).  It synthesizes phenazines in their reduced form, which are the likely end products in vivo (PubMed:23897464).
What are the official names of this protein?
Dihydrophenazinedicarboxylate synthase, Phenazine biosynthesis protein PhzG.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: AIM14_YEAS1
Sequence: MKESPLITLVKRHSETHFANIKYGYYVLIISLVYLIGLALLRAFGRRTPSRSSSAFKNKIIYRLYDIDPAIHLGILFFAVLIPFYYHYSLTTQSTVYLKRLGRLSYALIPLNLFLTLRPNWFLRKNCTYTDFIPFHKWFSRIITVIGLLHGIFFIIKWAIDDNVSLKQKLILKTFNFVGFIISILVLFLLICSIGPMRRYNYRLFYIVHNLVNVAFILLTPIHSRPGVKFPFLLLNCTLLFIHIINRIVFAKSLMILNKNANYSKTNLVHVRLPRAILPDYFEPGSHIRISPYRRINPLYWLLPSHPYTIASLAEDNSIDLIIKETSTAEPGSQIESLRSNPKSFHLDQEKTYTLINSYPPSVPEECYSQGTNIAIICGGSGISFALPLFRHFFNKENVKYLKMIWLIKNYSEYELVLDYLKTNGLTFEKKLSNNKRISVFISGEYTAETRLDEITTNIDDENSEYEMGSFNNEDEDLSISNFNSENADSNDNTPETSHSPTKENGSLIEVKSKHSFTLSSELKSFNNESAQVNQNETWLFSCGPPSLLQLSKKYCNDERINFVCETYGL
What is the function of this protein?
Probable cell surface metalloreductase.  May be involved in iron or copper homeostasis (By similarity).
What are the official names of this protein?
Probable metalloreductase AIM14, Altered inheritance of mitochondria protein 14.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family. AIM14 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRPD_PARXL
Sequence: MSITPQEALQRTIEHREIFHDEMLHLMRLIMRGELSPVMAAAIITGLRVKKETIGEITAAATVMREFARHVEVQDNSNFVDIVGTGGDGSHTFNISTATMFVSAAAGAKVAKHGGRSVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAMKNIAPVRRELGVRTIFNILGPLTNPAGAPNQLMGVFHADLVGIQVRVMQRLGAKHVLVVYGMDGMDEVSLGAATQVGELRDGQIHEYEIHPEDFGMQMVSNRTLKVADANESKAMLLEALDNKPGVAREIVTLNAGTALYSANVASSIADGIQLAREAIASGKARAKVDELARFTQQFKQ
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: PSA2_DROME
Sequence: MATERYSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVEMIYNHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVRPFGVSLLICGWDNDRPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLELDDAVHTAILTLKEGFEGKMTADNIEIGICDQNGFQRLDPASIKDYLASIP
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-2, PROS-Dm25, Proteasome 25 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYR_STAA1
Sequence: MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETHFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLAAHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPH2_SCHPO
Sequence: MLYRLSEKQQTDLRCNKLTVDGFELVKMLKELRLHNRNINFLEFLRGVQIVPSDSVFLGEIDENSHTQDNTTTSILKEKELYDGIPLLPSMAGVSMDPEREKKSELRLMKNQISAIINILFTVVGTVTAVWYCTSSLSIEKKIALCAFSAILVLVADTFLYVRYLSAQPVRTSKNHTRQIIYTWTTNDPVLQSNEQLAIELGAIPSLKEKKNQ
What is the function of this protein?
Required for vacuolar ATPase assembly.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein vph2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: KHSE_LISW6
Sequence: MRIRVPATSANLGPGFDSCGLALTLYLTLDIGGEAETWYIEHDIGGGIPHDETNVIIETALHLAPNLTPHHLVMTCDIPPARGLGSSSAAVVAGIELANTLAELNLSKEEKVRIAAEIEGHPDNVAPAVLGNWVVGAKLDGEDFYVRHLFPDCALIAFIPKKELLTSESRGVLPDALPFKEAVQASSIANVMIAAILRNDMTLAGEMMERDLWHEKYRSKLVPHLTQIREVAKSKGAYAACLSGAGPTVLVFAPRNIANTLQASLQTLEIDADVLLLDIEGSGAEVFY
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_HALSA
Sequence: MTVTIVGAQLGDEGKGGVVDLFGDATDVVVRYQGGDNAGHTVVAGGEEYKLSLVPSGVVRGKTGVLGNGCVINPETLFEEVDALRERGLDPDVRLAKRAHVILPFHRELDGAEEAAKADSDSEIGTTGRGIGPTYEDKIGRRGVRVGDLLNEDALRDRLEYLVDAKRAIYEDVYGFDASETDGAFDIDAIHEQCLAYADRIRDEDLAVNAGDYLADRIADGDNVMLEGAQGTSLDIDHGNFPYVTSSNPTAGYAATGSGLGPTTVGQGEIVGIIKAYLSRVGSGPMPTELDGDQAEYIREEGGEYGTVTGRPRRVGWLDMPMLRHAARANGFTGIAINHLDVLAELDEVNVGHAYERDGERIHTLPATTEAWRDCDPVMKSFDGWSAFDPAVVADAGYSALPDNAQAYVEYVEAELDTPAYVLGVGPGREESVIRQNPFE
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BUCCC
Sequence: MKFVDSVIINVSAGKGGDGCISFRREKFVPKGGPDGGNGGDGGNIWIVSNTNINTLTDYRIKKIFQSENGKNGLNSNRSGKNGKDIYIPVPLGTRIIDNDTKKIIIEILKINQKFLVAKGGKRGLGNTNFKSSINQTPRKKTYGTLGENKNILLELILIADIGTLGLPNSGKSTLITSMSNAKTKIDIYPFTTLIPILGTVKAKKKKFIIADIPGIIKNASLGIGLGIKFLKHLSRCKLLLHIIDITINKKKINKIRYIILKELKNFNKKLFQKTRWLIFNKIDLLKPKKISQIKKYIKKKIEKNKKYYFISAKKNIGIKKLSKDIIKYLYKKNKEYI
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNAA_ECOLI
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Almost exclusively localized in foci near 1 cell pole in mid-to- late exponential phase, fewer cells have foci at stationary phase; polar localization depends on the minCDE operon.
Protein: SYA_LACLA
Sequence: MKTMTSAEVRQMFLDFFKSKGHTVEPSQSLVPVNDPTLLWINSGVATLKKYFDGSVVPENPRLTNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRKEAIAFAWELLTSSEWFEFPAEKLYITYYPADKDTYNRWVEVGVDPTHLVPIEDNFWEIGAGPSGPDTEIFFDRGEVYDPEHVGLKLLAEDIENDRYIEIWNIVLSQFNADPSIPRSEYPELPQKNIDTGMGLERMVCIIQGGKTNFDTDLFLPIIREIEKLSGKTYSPDSENMSFKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRAVMHGKKLGIQGKFLASLVPTVGKIMQSYYPEVLEKEDFIMQIIDREEETFNRTIDAGQKLIDELLLNLKSEGKDRLEGADIFRLYDTYGFPVELTEELAEDEGFKIDHEGFKVAMKAQQERARAAVVKGGSMGAQNETLSSIEVESEFLYEDKTTQGKLLVSIQDDEIVDEVSGKAQLVFDVTPFYAEMGGQVADHGVIKDAEGQVVANVLDVQHAPHGQNLHSVETLSPLKVGESYTLEIDKERRAAVVKNHTATHLLHAALHNIVGNHALQAGSLNEVEFLRFDFTHFAQVTKEELAEIERQVNEVIWQSLKVETVETDIATAKEMGAMALFGEKYGKNVRVVKIGDYSIELCGGTHTQTTSEIGLFKIVKEEGIGSGVRRIIAVTGQKAYEAFKDAENTLNEVATMVKAPQTSQVLAKVTSLQDELKTAQKENDALAGKLAASQSDEIFKNVQTAGSLNFIASEVTVPDANGLRNLADIWKQKELSDVLVLVAKIGEKVSLLVASKSSDVKAGNLVKELAPFVDGRGGGKPDMAMAGGSKAAGIPELLAAVAEKLA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLDA_THEMA
Sequence: MITTTIFPGRYVQGAGAINILEEELSRFGERAFVVIDDFVDKNVLGENFFSSFTKVRVNKQIFGGECSDEEIERLSGLVEEETDVVVGIGGGKTLDTAKAVAYKLKKPVVIVPTIASTDAPCSALSVIYTPNGEFKRYLFLPRNPDVVLVDTEIVAKAPARFLVAGMGDALATWFEAESCKQKYAPNMTGRLGSMTAYALARLCYETLLEYGVLAKRSVEEKSVTPALEKIVEANTLLSGLGFESGGLAAAHAIHNGLTVLENTHKYLHGEKVAIGVLASLFLTDKPRKMIEEVYSFCEEVGLPTTLAEIGLDGVSDEDLMKVAEKACDKNETIHNEPQPVTSKDVFFALKAADRYGRMRKNLT
What is the function of this protein?
Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone).
What are the official names of this protein?
Glycerol dehydrogenase, GDH, GLDH.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: NFUA_SHIDS
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: RL22_CUPPJ
Sequence: MEVKAIHRGARISAQKTRLVADQIRGLPIERALNVLTFSPKKAAGIVKKVVESAIANAEHNEGADIDELKVKSIFVDKATSLKRFTARAKGRGNRIEKQTCHITVTLGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RHA2_CAEEL
Sequence: MGKRKTKEDNASEDYDANELMIVPGEKRKKLEKSGEKSATGGKKNRNFAKEKEVAKLTKQAKRKLAAVQSRKALKQTQEELFAGLAEFQLDPSKLCQLSSSTKLSKEPEKAPVFPEKLKVFSGKTKTEAKRTQQDYYPTDDESSSEEEEEEEEGDNDIEDAGNTVEVKIEPIDLDDVDEAIDGNPETNLDQIVVKREDDEESDNEDILALPTTTVINRKKVIVERSKEIQKSRAELPIFAEEMRIVEAINENLVTVVCGETGSGKTTQIPQFLYEAGYASEGELIGITEPRRVAAIAMAQRVGVELAKPDEVSYQIRYEGTRSETTNILFMTDGVLMKEMEQDVMLKKYSVILIDEAHERSMYSDVLIGMLSRIVPLRSKTARPLRLVIMSATLRLDDFTHKKLFPLLTPKVIKVDARQFPVSVHFEKRTPDDYIASAFRKTCRIHETLPPGAILVFVTGQHEVKQLITKLKKRYPVVYETDKNGEVLVKGTKEWKEKKVEAAKSIKLEDFKEETPETEDFEDVDDGLMDGDDMNERGAAEAFDDYEEFENGDGDLSDGKVENSIGAPPADCEPLYCLPLYSLLSMGKQRRVFDETPAGMRLCVISTNVAETSLTIPGVKYVIDGGFEKRRLYDSITGVSRFAVCRISQASGDQRAGRAGRISAGHAYRLYSSAVYQDFVKFADPEILSKPADQLVLHLKSMNIVKVVNFPFPSAPDEQMLESAEKRLCRLGALSESTKNGKTEARITKLGKTLAVFPLAPSYAKFIAMADQHNLMSHAILLISLLSVREPLIPVSSLRGDTPEETKELMKNVLKERRRWCSHTGARRLGDLKVLMHAASVAEQIKYNARECEKVGLRVKALVEARKLRQQLTNIVNASCKKEHAAALDSDLPPPTDQQAQLLRQMVVASFSDRLARRVDRSVGQEEVQKGAYETTLIKGHVFIDPCSVVFTEEPEFVIYQELVQVNEKKLMTSVCAVDKEWLSRLAESYCNYGEQDKNQEPIYDPVKDMVVKTVKVTFGPLNWELPNENRSVPHDIMMYRYFALFLLDGLVFEKLKEYTPKLLAPPSTMVKSWAKLQKRTEMLLNKLIEKEVTTRSSLKEQWLKNENWLLEEYLEWVPESVHQQISLMWPPLEDHEKTIKMGRNKKY
What is the function of this protein?
Probable ATP-binding RNA helicase.
What are the official names of this protein?
Putative ATP-dependent RNA helicase rha-2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
Protein: AF1L1_XENTR
Sequence: MQERLRILDQLLPELNVLLRLLDHEFLSATTREKQSAVCSILRQLQPAPGDELDFQYMNTAAYHNGTSFVESLFEEFDCDLHDLHDMQDEYRDSSENLSCQLPPPPSAPPPPLPTTPPPEDYYEEAVPLGPGKFTEYITSRNSSSPPNSIEDGYYEEADNNYPMTRINGEQKNSYNESDGLSSSYESYDEEDEEGKAQRLMLQWPSQEASLHLVRDSRICAFLLRKKRFGQWAKQLTLIKDNKLLCYKSSKDRQPHLEIPLALCNVAYVPKDGRRKKHELRFSLPNGEMLVLAVQSREQAEEWLRVIKEVISPSTGSSPASPALRHRLDLDKRLSHDKTSDSDSAANGENSSLSSGKENRDTGKCRKGGLAELKGSMSRAAGKKITRIISFSKKKQSTEEHHTSSTEEEVPCCGYLSVLVNQCWKERWCCLKGHTLYFHKDRNDLRTHINAIALRGCEVSPGFGPLHPFAFRILRQSQEVTALEASCSEEMGRWLGLLLAQTGSKTKPEALHYDYVDVETIANIATAVRHSFLWATSSHSSTSDLRLYDDVSYEKVEDPKRAPGVAQVKRHASSCSEKSRRVESEVKVKRHASNANQYKYGKTRAEEDARKFIVEKEKLEKEKEAIRSKLIAMKRERRELKEMLKNCSGKQQKEMEERLAMLEEQCKNNEKVRVDLEIQLTEVKENLKKSLAGGPTLGLAVTGKSENPPQKSQQPRSPPDRLLPVNSAAEMRRRSPSIAASSKGKVLQKAKEWEKKKP
What is the function of this protein?
May be involved in podosome and invadosome formation.
What are the official names of this protein?
Actin filament-associated protein 1-like 1, AFAP1-like protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, podosome. Cell projection, invadopodium. Cytoplasm, cytoskeleton, stress fiber.
Protein: NTPPA_BORPE
Sequence: MSDATLAADPPRLYLASASPRRRELLLQIGLTHTVLRVPAPPGEDEPQHPGEAACDYVRRTARDKAERGQAWLHSQQLPDLPLLAADTTVILDGIVLGKPADRADALRMLAALSGREHEVHAAVALCHQGRLYEDVSITRVRMRALEQAELQRYCDSGEPYGKAGAYGIQGLAGAFVSHIAGSYTGVMGLPIYETAALLRSAGIAVP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_CERS4
Sequence: MSTILDRIKAYKLEEIAARKAERPLVAVEDAARAAPAPRGFARALSTAAATGYGLIAEIKKASPSKGLIREDFDVPALARAYETGGATCLSVLTDGPSFQGADDFLRQAREAVKLPCLRKDFLYDTYQVAEARALGADCILIIMASVTDSQALELEAAASHWGMDVLVEVHSREELARAEHLKSRLIGINNRNLDTFEVSLDVTRDLARRVPEDRLIVSESGLHTPEDLADLARYGARCFLIGESLMRQADVEAATRAILADPLTAQGGV
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: PHB1_DICDI
Sequence: MQSFLNKLIPLALTVGTGLSLAQSSMYTVDGGQRAVIFDRISGVKEKSVGEGTHFIMPWLQKPIIFDIRSSPRNIKSDTGSKDLQTVSVTVRVLFRPDVEHLPSIFSKLGLDYDERILPSLGNEVLKSVVAQYDATELITQREVVSKEIRESLMKRAKEFNLLLDDVSITHLSFSQDFTNAIEHKQVAQQEAERSKYIVMKNEQEKKANIIRAEGEAEAAKLIGQAMGNSAAFIELRRIEAYKDITESLSKSKQVTYVPTSGNLLMNLNKQ
What is the function of this protein?
Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins.
What are the official names of this protein?
Prohibitin-1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the prohibitin family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: HDA_ECOK1
Sequence: MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: PYRG_LACDB
Sequence: MTKYIFVTGGVVSSLGKGITASSIGRLLKNRGLKVTMQKFDPYINIDPGTMNPYQHGEVFVTDDGTEADLDLGHYERLVDVRTSKYSNVTTGKIYQEVLQRERRGDYHGGTVQVIPHVTNMIKEKVMRAAQMTDTDVVISEIGGTVGDMESTPFMEAIRQMRREVGSENVMYVHVTFVPYLRAAKELKSKPTQQSVSMLRSIGIQPNMLVLRSEMPVPQEMKDKISTFTDVPVDYIVESLDAPSLFDVPLSYQEQGVDQKVVDFLHIDSPKPVADMDEWRRMDERAKNLKYKTKITLVGKYVELEDAYISVTDALQHAGYLYNSKIEVEKIQAEDITEDNVAELLKDTQGLIVPGGFGIRGLDGMITSIKYAREHDIPFLGICLGMQMASVEFARNVLHLEDANSAEAEPNCKNNIIDLMADQRDQEKIGGTLRLGLYPAMLKAGTKTRECYDGQEVIQERHRHRYEFYNKYREDFEKAGMTFSGVSPDNHLVEIVEITDKKFFVAAQYHPEFLSRPNRPEGLFKGFIGAASGLQVDKF
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: CP19A_LAGAC
Sequence: MVLEVLNPRHYNITSMVTEVAPVASIAILLLTGFLLLVWNYEDTSSIPGPGYFLGIGPLISHCRFLWMGIGSTCNYYNKTYGEFVRVWICGEETLIISKSSSMFHIMKHSHYTSRFGSKLGLQCIGMHEKGIIFNNNPALWKAVRPFFTKALSGPGLVRMVTVCADSITKHLDRLEEVRNELGYVDVLTLMRRIMLDTSNKLFLGIPLDERAIVVKIQGYFDAWQALLLKPDIFFKISWLCRKYEKSVKDLKDAMEILIEEKRQRISTAEKLEDCMDFATELIFAEKRGDLTKENVDQCILEMLIAAPDTMSVSVFFMLFLIAKHPQVEEAIMKEIQTVVGERDIRIDDMQKLKVVENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFARNVPYRYFQPFGFGPRACAGKYIAMVMMKVTLVTLLRSFHVQTLQGRCIEKMQKKNDLSLHPDETSDLLGMIFIPRNSDKCLDH
What is the function of this protein?
A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstenedione) and testosterone to the C18 estrogens, estrone and estradiol, respectively.  Catalyzes three successive oxidations of C19 androgens: two conventional oxidations at C19 yielding 19-hydroxy and 19-oxo/19-aldehyde derivatives, followed by a third oxidative aromatization step that involves C1-beta hydrogen abstraction combined with cleavage of the C10-C19 bond to yield a phenolic A ring and formic acid.  Alternatively, the third oxidative reaction yields a 19-norsteroid and formic acid.  Converts dihydrotestosterone to delta1,10-dehydro 19-nordihydrotestosterone and may play a role in homeostasis of this potent androgen.  Also displays 2-hydroxylase activity toward estrone.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Aromatase, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Protein: ESN_DROPS
Sequence: MQQQPQPQPLPHSSYYTQTESELLQIEAGGTGLTFPPHRSEMAATSSQLQQASMSSNVASTATSSNLDVPSGGSTGSGSGGQTTSHFVSPLQRRHCQPPSHLPLNSVASPLRTASYKTAAAVAGHGFHHSHHQQLDFQRNSQSDDDSGCALEEYTWVPPGLRPDQVRLYFSQLPDDKVPYVNSPGEKYRVKQLLHQLPPQDNEVRYCHSLSDEERKELRIFSAQRKREALGRGAVRLLSDERPCKGCEESLSGGDIVVFAQRLGAQLCWHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPRCSACDEIIFSDECTEAEGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLGCFDTMFAEYCDYCGEVIGVDQGQMSHDGQHWHATDQCFSCCTCRCSLLGRPFLPRRGTIYCSIACSKGEPPTPSDTSSGPQLRPTHRASTSSQIARSPRRSGDRDRERESSRKANHGHGPVKGTGSAGDLLERQERKRMEAAGVADLLLGGGVPGMPRPAHPPPIDLTELGISLDNICAGDKSIFGDSQLTSSMPDMLLSKAEDSHSYQSIDKINLNSPSNSDLTQSTQELANELELDNDPVRELPHDGYEQLFANNRNTKKGHELQDMQGEEDGEQLDNRPLKEVRFHSVQDTMSRSKSYTDNSNARRRRRRRNQSRSSSEMQINQTNLRLHNAQTQAGTGTGAHNLLNNLDNCDVASICSTCSSSSSSDMDDYVYRLPARKHYGGVRVAYVPNDALAYERKKKLAQDPSLAAAASAAVPGVPGVMNESKNCTIS
What are the official names of this protein?
Protein espinas.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.