PharMolix/UniProtQA huggingface dataset:
Protein: MNHA2_STAA2
Sequence: MSLVYLLIAILVIMAMILLMSKRRALAKYAGYIALVAPVISSIYFLIQIPSVAKLQYLSTSIPWIKTLDINLDLRLDGLSLMFSLIISLIGIAVFFYATQYLSSRKDNLPRFYFYLTLFMFSMIGIVLSDNTILMYIFWELTSVSSFLLISYWYNNGDSQFGAIQSFMITVFGGLALLVGFIMLYIMTGTNNITDILGQADHIKNHGLFIPMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLLRFTPLLGLSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMAMVGIGGGYAQHQQDAIASIYVFVLFGALFHLMNHAIFKCALFMGVGILDHEAGSRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQLSQFSLISMIAIVFVGVIASIFTFTYALYMVKEVFWTKYDSKVFTKKNIHEPWLFSLPSLILMVLVPVIFFVPNIFGKGIIVPALRGVSGGNHQIDPLAPHVSQWHGFNIPLLLTIIIILLGSVLAIKVDWKKVFTGKIRQISVSKGYEMVYRHFEKFATKRFKRVMQDRLNQYIIMTLGIFMIIIGYGYIRIGLPKVHQLHVSEFGALEIILAIVTVTIGISLIFIRQRLTMVILNGVIGFVVTLFFIAMKAPDLALTQLVVETITTILFIVSFSRLPNVPRSNANKKREIIKISVSLLMALIVVSLIFITQQTDGLSSISDFYLKADKLTGGKNIVNAILGDFRALDTLFEGLVLIITGLGIYTLLNYQDRRGQDERE
What are the official names of this protein?
Putative antiporter subunit mnhA2, Mrp complex subunit A2, Putative NADH-ubiquinone oxidoreductase subunit mnhA2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FPG_ALTMD
Sequence: MPELPEVEVSRLGVSPHLIGNTITRVVVRERRMRWPIPQEVAKVEGQKVTAVKRRAKYLLIETAQGTLILHLGMSGKLRVIDASTPVIKHDHVDIVLSTGKCLRFNDPRRFGAVLYQAPDTHIPMLDNLGPEPLTDDFDDTRLFTLSRNRKGPVKNFIMDNAIVVGVGNIYANEALFLAGIDPRRAAGNISAARYKSLTATIKQVLAKAIEQGGTTLKDFAQTDGKPGYFAQHLNVYGRKGEPCEACGKAIESKVIGQRNTFFCTRCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: ATC2_CRYNH
Sequence: MSRNNPPPVIITTDPDSPALHSAPSTPPPNQRPTPTLVIPGSPASESSHPESPQGNDPFRLSPNARLYPPGSGHSPTPSYSSALTPPSPTLTSSSSVHFSDELPTPSSPNPKTSLALRDNHPDARSGMETLQTVDENDPQRRHARGWSIGTWSSAAPTADGYSMKKPLIRTATGASEVDGDRGEDDANKKGKKDKKGKKGKKDKEEPPSAHLDPDKDKTDPTPFREKPSRLAMLVDPKSLEDLEKIGGVSGLLEGLGVDGEKGLAVGTDEGNAENGAPRSSADMPGGNGPQWRASMDRRRDIYGRNDLPRRKSKSLLLLMWLAFKDKVLILLSVAAVVSLALGLYQDLGTPPKIIYNDECPDGCEEAQVDWVEGVAIVVAIIIVVLVGSINDWQKERQFKKLNEKREDRNVKVIRGGSEMVINVKDVVVGDVCLLEPGEIIPVDGIFLRGHNVRCDESGATGESDAIKKFSYDECIKERDNLQPGQRQKKDCFLISGAKVLEGVGEYVVIAVGPTSFNGRIMMAMRGDADETPLQIKLNHLAELIAKLGGASGLLLFIALMIRFFVQLKTNPDRSANDKAQSFIQILIIAVTLVVVAVPEGLPLAVTLALAFATKRMTKQNLLVRVLGSCETMANATVVCTDKTGTLTQNEMTVVAGSLGVHGKFVKDLSDNASRSNANEGEGHSVHGDFSFDMSQLNDYASSSLQTLFNEAICINSTAFEDKNEEGKLNFVGSKTETALLRFAKDMEWPNYRQVRESAEIVQMIPFSSELKAMGVVVRKDDTYRLYLKGASEVLSNNCTRHVVVHQDGNKGDDIETTEFDDDTMSNISKTIIFYANQSLRTIALCYRDFESWPPAGTEKDGADEVPYEAIAKDMTLIAITGIEDPLRPGVREAVEKCQLAGVAVKMCTGDNVLTARSIASQCGIFTAGGVVMEGPLFRKLSDSDRLEIAPRLQILARSSPEDKRLLVKTLKSMGEVVGVTGDGTNDGPALKLANVGFAMGIAGTEVAKEASDIILMDDSFKNIVLAIMWGRCVNDSVKKFLQFQISVNITAVFITFISAVASSSEESVLTAVQLLWVNLIMDTFAALALATDPATESSLDRKPDRKNAPLITVEMFKMIMVQAIYQIIVCLVLHFAGLKILGLEDNDQNNTELGALVFNCFVFCQIFNQLNCRRLDRKLNVLEGFWRNWYFIIIFLIMVGGQILIVEVGGAAFQVTRLGGRDWGITLVIGALSLPIGALVRLTPTGPFARLLVKLHIYADPNKLPELSPEAEEEQYSYNPALSRVKDNLSTYARIRGGRLRASSMVAKSRNAQLRDADIQFPSLLTMVPTVIAGTVGAGAHWVTPHNSIGLSNPAGQDPSYSTAELFKGKVQLHPRTNPDDPLYAKFGLQPPESRGSSVSGAEGLSSGDANNV
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium (By similarity).  Transports calcium to the vacuole and participates in the control of cytosolic free calcium (PubMed:23895559).
What are the official names of this protein?
Calcium-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: CMOB_HISS2
Sequence: MFDFRPFYQQIATSTLSAWLETLPLQLKQWEKQTHGDYIKWSKIIDFLPHLTADHIDLKSAVKAETKTPLSSGERQRIIHHLKQLMPWRKGPYHLYGIHIDCEWRSDFKWERVLPHLAPLQNRLVLDVGCGSGYHMWRMVGEGAKMVVGIDPTELFLCQFEAVRKLLNNDRRANLIPLGIEEMQPLAAFDTVFSMGVLYHRKSPLDHLTQLKNQLVKDGELVLETLVVEGDINTILVPTDRYAKMKNVYFIPSVLALINWLEKCGFHNIRCVDVETTGLEEQRKTDWLENESLIDFLNPQDHSKTIEGYPAPKRAVILANK
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: CEL2A_HUMAN
Sequence: MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVIANN
What is the function of this protein?
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism.  Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity.
What are the official names of this protein?
Chymotrypsin-like elastase family member 2A, Elastase-2A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Elastase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NHAB_AERHH
Sequence: MPISLGQAFARNFLGNAPQWYKAAILLFLLINPIAFYLDPFIAGWLLVVEFIFTLAMALKCYPLQPGGLLAIEAVLIGMTSAKQVKHELVANIEVLLLLVFMVAGIYFMKQLLLYVFTKLLIRIHSKTLLSLAFCLVSAFLSAFLDALTVIAVVISVATGFYAIYHKVSSGKEFGNPHDHTDDDAVNELNRQHLDDFRAFLRSLMMHAAIGTALGGVCTLVGEPQNLIIGEQAGWNFGEFAIRMSPVTVPVFICGLLTCVLVEKCRWFGYGAKLPDAVRRIMEDYNRYEEAGRTAQDKAKLIVQAAIALWLILGLAMHLAAVGLIGLSVIVLATSLTGITEEHSLGKAFQEALPFTALLAVFFSVVAVIIDQQLFKPVIQWVLAAEPDAQLALFYLANGLLSMVSDNVFVGTVYINEVKTALLNNAISREQFELLAVAINTGTNLPSVATPNGQAAFLFMLTSALAPLLRLSYGRMVWMALPYTLVLGLVGFFSVEMLLGPLTDWFYQAGWLVLDNVAPAALPVLH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOD2_SORC5
Sequence: MSQVIFSVDRGGAEPGAEMDDEMTLNMGPHHPSTHGVLRFVISTDGEIIRKAVPDVGYLHRSIEKIGERCTYSGFMPYTDRVDYIAAMFANEAWASACEKLMGIEVPKRAQYLRVISCELNRIGSHMIALGAMAMDVGAVTPFPWALREREYINDFIEELCGARLTFNYHRIGGVSFDMPKGWADKVKHWLDRFEPIMVEFDRLISLNDIFIKRLANVAVVTAEEAKDWGLVGPNLRGSGVKWDLRKEDAYSVYPELEFDVPVGRGRYGTVGDCWDRFYVRVEECRESAKILRQALDKIDEHPEDDILGKLPKKMRPDGEAYARIESARGDMGCYVIGRGAEEAYRARFRTGSFTAMAMIEAKSPGLFLADLVALIASFDVVAPEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 2, NADH dehydrogenase I subunit D 2, NDH-1 subunit D 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PME1_ARATH
Sequence: MDSVNSFKGYGKVDEAQDLALKKKTRKRLLLLSISVVVLIAVIIAAVVATVVHKNKNESTPSPPPELTPSTSLKAICSVTRFPESCISSISKLPSSNTTDPETLFKLSLKVIIDELDSISDLPEKLSKETEDERIKSALRVCGDLIEDALDRLNDTVSAIDDEEKKKTLSSSKIEDLKTWLSATVTDHETCFDSLDELKQNKTEYANSTITQNLKSAMSRSTEFTSNSLAIVSKILSALSDLGIPIHRRRRLMSHHHQQSVDFEKWARRRLLQTAGLKPDVTVAGDGTGDVLTVNEAVAKVPKKSLKMFVIYVKSGTYVENVVMDKSKWNVMIYGDGKGKTIISGSKNFVDGTPTYETATFAIQGKGFIMKDIGIINTAGAAKHQAVAFRSGSDFSVYYQCSFDGFQDTLYPHSNRQFYRDCDVTGTIDFIFGSAAVVFQGCKIMPRQPLSNQFNTITAQGKKDPNQSSGMSIQRCTISANGNVIAPTYLGRPWKEFSTTVIMETVIGAVVRPSGWMSWVSGVDPPASIVYGEYKNTGPGSDVTQRVKWAGYKPVMSDAEAAKFTVATLLHGADWIPATGVINQLS
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin (By similarity).  Demethylates protein phosphatase 2A (PP2A) that have been reversibly carboxymethylated by LCMT1.  Acts as negative regulators of genes involved in salt stress response (PubMed:28741704).
What are the official names of this protein?
Pectinesterase 1, PE 1, Pectin methylesterase 1, AtPME1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall. Golgi apparatus membrane. Note=Cleaved in the Golgi apparatus by SBT6.1 (S1P) after the Arg-Arg-Leu-Met (RRLM) and Arg-Arg-Leu-Leu (RRLL) motifs. This processing is required for extracellular targeting.
Protein: ACYP_NATPD
Sequence: MSDRIRAHVYVSGRVQGVYYRANTRDTARERDIDGWVRNLDDGRVEAVFEGPREAVESMVGWCHTGSPKARVESVDAAYDDPEGVDGFEIRR
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: TAG2N_AGEOR
Sequence: MRAIISLLLISAMVFYIIAAVPEEEGLQLSEDERGGCLPHNRFCNALSGPRCCSGLRCKELSIRDSRCLG
What is the function of this protein?
Insect active toxin causing rapid but reversible paralysis in crickets.  No activity shown in mammals.  Does not show effect on mammalian voltage-gated calcium channels (By similarity).
What are the official names of this protein?
U2-agatoxin-Ao1n, U2-AGTX-Ao1n, Toxin-like structure Agel_13.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 01 (U2-agtx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RET3_CRISP
Sequence: HPIQNLFQPSLVLDM
What is the function of this protein?
IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.
What are the official names of this protein?
Retinol-binding protein 3, Interphotoreceptor retinoid-binding protein, IRBP, Interstitial retinol-binding protein.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Note=Interphotoreceptor matrix that permeates the space between the retina and the contiguous layer of pigment epithelium cells.
Protein: AROC_BURP6
Sequence: MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMALTEADVQLELDRRKPGTSRHVTQRQEPDQVEILSGVFEGVTTGAPIALLIRNTDQRSKDYGNIAETFRPGHADYTYWQKYGVRDYRGGGRSSARLTAPVVGAGAIAKKWLRERFGVEVRGYMSALGEIEIPFVDWSHVRENPFFAPNADIVPQLEGYMDALRKDGDSIGARIDVVASGVPVGWGEPLFDRLDADIAHAMMGINAVKGVEIGAGFASVAQRGSVHGDELTPDGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITRAGEPAVVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVSSATPRIAARAPDAQ
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: TM192_MOUSE
Sequence: MAAAGRLEDSSLDILQSMDDDPLLDTQPLPHHSLQAQFRPRFHPLPTVIIANLLLLIHVVFVVLAFLTGVPCLYPNPTEDKCPENYTSPLKVQTAIILGKLILWILHLLFERYVQYHHRKVRSRGYSQIYRSTRHLKTLALTIHSSGNTALLLLLCVQHSFPEPSKLYLELILAVLALELICSLSCLILYIVKIRRFNRAKPLPDVLEEEKIYAYPSNTASETGFRTVSSLEEIVEKQEDIIVYLKRHNALLSKRLLELATQPART
What are the official names of this protein?
Transmembrane protein 192.
What is the protein family that this protein belongs to?
Belongs to the TMEM192 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Late endosome.
Protein: LOLD_BLOFL
Sequence: MVNKNINDIPPILCCSNIIKRYQYSNFSITVLDGITMSIEYNKIIAIIGASGSGKSTLLHIMGGLDKPTSGDVFLEGRALNKLSDKDCSIMRNTSIGFIYQFHHLLPDFSVLENIAMPLLIKGLKFAIAKHKAQFILELIGLNNLCDRYPCELSGGESQRVAVARAIINNPPLVLADEPTGNLDESNSNNVFKLLEKINLWYGTTFVIATHDLSLAKKCHKIYIVSNGMLKISTI
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: THIC_HALMA
Sequence: MTQMAAARNGTVTEEMERVAEREGVDPAFVRQQVADGQAVIPANVGHDSLDPMIIGREFATKVNANIGNSEETSDIEGELEKLHTAVHYGADTVMDLSTGRNLDEIRSANVTHSPVPVGTVPIYEAVKRASDPSEITHELLLDVIEKQAKQGVDYMTIHAGVRMEHLPLTDGRKTGIVSRGGSILAKWIEENGMENPLYTKFEAICEIFREYDVTFSLGDGLRPGCLADAGDDAQFAELDTLGELTRTAWKHDVQVMVEGPGHVPMDQVAEQVERQQEVCDGAPFYVLGPLVTDVAPGYDHITSAIGATEAGRAGAAMLCYVTPKEHLGLPEKSDVRDGLAAYRIAAHAADVANGREGARDWDDALSEARYAFDWREQFDLALDPDRAREYHDQTLPGDNYKEARFCSMCGVEFCSMRIDQDARSDGDMESIEADADDRTPLEDSSAAAVNRPPVGTHDGADIPGPDADMPADTEGSADD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: NUSB_CLOTE
Sequence: MKRKKSREMTMQLLFEMMIKKENYVEIINTLKEALTEEEDINSILGEKKEMDEERIDLDEVDLEYLIHTLKGVEENSKVLDEHIEKYLKNWTLNRLAKVDLAILRLCSYEILFSNEVPDNVAINEGVELAKKYGDDKSPAFINAVLDKIAKQM
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ORG3_ARATH
Sequence: MCALVPPLFPNFGWPSTGEYDSYYLAGDILNNGGFLDFPVPEETYGAVTAVTQHQNSFGVSVSSEGNEIDNNPVVVKKLNHNASERDRRRKINSLFSSLRSCLPASGQSKKLSIPATVSRSLKYIPELQEQVKKLIKKKEELLVQISGQRNTECYVKQPPKAVANYISTVSATRLGDNEVMVQISSSKIHNFSISNVLSGLEEDRFVLVDMSSSRSQGERLFYTLHLQVEKIENYKLNCEELSQRMLYLYEECGNSYI
What are the official names of this protein?
Transcription factor ORG3, Basic helix-loop-helix protein 39, AtbHLH39, bHLH 39, OBP3-responsive gene 3, Transcription factor EN 9, bHLH transcription factor bHLH039.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSTB_ECOL5
Sequence: MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNSQDIALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IBPB_SHIFL
Sequence: MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAENMEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GABD1_MYCLE
Sequence: MSIATINPATGETVKTFTPTTQDEVEDAIARAYARFDNYRHTTFTQRAKWANATADLLEAEANQSAALMTLEMGKTLQSAKDEAMKCAKGFRYYAEKAETLLADEPAEAAAVGASKALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNVPQCALYLADVIARGGFPEDCFQTLLISANGVEAILRDPRVAAATLTGSEPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRVQNNGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATESGRAQVEQQVDAAAAAGAVIRCGGKRPDRPGWFYPPTVITDITKDMALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFIDNIVAGQVFINGMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWIA
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate.  It is believed to be the main source of succinate semialdehyde dehydrogenase activity in Mycobacterium (By similarity).
What are the official names of this protein?
Succinate-semialdehyde dehydrogenase [NADP(+)], SSADH, SSDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: CNOT9_BOVIN
Sequence: MHSLATAAPVPTALAQVDREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ
What is the function of this protein?
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Involved in down-regulation of MYB- and JUN-dependent transcription.  Enhances ligand-dependent transcriptional activity of nuclear hormone receptors.  May play a role in cell differentiation.
What are the official names of this protein?
CCR4-NOT transcription complex subunit 9, Cell differentiation protein RQCD1 homolog, Rcd-1.
What is the protein family that this protein belongs to?
Belongs to the CNOT9 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, P-body. Note=NANOS2 promotes its localization to P-body.
Protein: PGK2_THEKO
Sequence: MIIVTDSERKIRLPFSRGILTRSITLAGIDVGIAYAIATEVQKELEWKGKKSVTTEEIRELTYQKLLEKGLREEAKRYLFWRELRRRKVRLTVLLGGATGVGKSTIATELAFRLGIRSIIGTDTIREVMRKIIAKELLPDIHVSSFLAERVVKAPKNSDPLIYGFETQVKHVSVGIKAVLERARREGLNTLIEGIHVVPGFVEPREDEFMYVIAVPKKDYLIAHFYERARYSQRDAEKYVKHVDRIMRIQDYLVERAREHGIPVIENVELESTVSTILADMMKKLEEMGV
What is the function of this protein?
Catalyzes the phosphorylation of 2-phosphoglycerate to 2,3-diphosphoglycerate.  Involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant.
What are the official names of this protein?
2-phosphoglycerate kinase, 2PGK.
What is the protein family that this protein belongs to?
Belongs to the 2-phosphoglycerate kinase family.
Protein: RF3_SHESM
Sequence: MSDNKVEVDKRRTFAIISHPDAGKTTITEKVLLFGNALQKAGTVKGKKSGQHAKSDWMEMEKDRGISITTSVMQFPYGGALVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEDRTIKLMEVTRLRDTPIVTFMNKLDRDIRDPIELMDEVEDVLNIACAPITWPIGSGKEFKGVYHILRDEVVLYQSGMGHTIQERRVIEGIDNPELDKAIGSYAADLRDEMELVRGASNEFDHQAFLKGELTPVFFGTALGNFGVDHILDGIVEWAPKPLPRESDARMIMPDEEKFTGFVFKIQANMDPKHRDRVAFMRVCSGRYEQGMKMHHVRIGKDVNVSDALTFMAGDRERAEVAYPGDIIGLHNHGTIRIGDTFTQGEKFRFTGVPNFAPEMFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLDTNDLIVGAVGVLQFEVVVGRLKSEYNVEAIYEGISVSTARWVYCKDERKLEEFRRKCSQNLALDGGDNLTYIAPTMVNLNLSMERYPDIEFAKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_MACCJ
Sequence: MNLVLNGQDLTIESIKVLIAQDQNVEICEEALSRVKQSRKIVDDIIADQETVYGITTGFGLFSDVLIDQDKYEDLQLNLIRSHACGIGEPFNDDVALVMMILRLNTMLKGHSGVSTALVEQLVFFINQRIFPVIPAQGSLGASGDLAPLSHLALALVGEGEVIYKGVRQESSKVLQSLNRAPHTLQAKEGLALINGTQAMTSQGVISYIEAEQLAYDAEWIAALTHQALNGIVDAYDAHVHIVRNSKEQLSVANRMLDWLEGSSLTTRQGELRVQDAYSLRCIPQIHGASFQVLNYVKEKLECEMNAANDNPLIFDKDDETLVISGGNFHGQPVAFALDFLKIGVSELSNVSERRIERLVNPQLNGDLPAFLSPHPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIASRHGYQIVENVRNVLAIECVIALQAVELKGVDKLSQKTKEKYEEYREFVPSITEDRQFHKDIKVVSDYLKRSAYKK
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_ACIAC
Sequence: MARITVEDCLEHIPNRFQLVLAATYRARMLSQGHAPKIESRNKPAVTALREIAEGKIGLEMLKKVPG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: CSP_PLACG
Sequence: MKNFNLLAVSSILLVDLFPTHCGHNVDFSRGINLNGVSFNNVDASSHGAEQVRQSASRGRGLGENPKDEGADKPKKKDEKQVEPKKPRENKLKQPREDGAAAAGGGGNDGAAAAGGGGNDGAAAAGGGGNDGAAAAGGGGNDGAAAAGGGGNDGAAAAGGGGNDGAAAAGGGGNDGAAAAGGGGNDGAAAAGGGGNDGAAAAGGGGNDGAAAAGGGGNGGAAAAGGGGNDGAAAAGGGGNDGAAAAGGGNGGAAAGGGGNGGAAAGGGNGGAAAGGGNNARAGDQQPPAGGNKKAGEAGGNAGAGQAQNNEAANVPNAKLVKEYLDKIRSTLGVEWSPCTVTCGKGVRMRRKVSAANKKPEELDANDLETEVCTMDKCAGIFNVVSNSLRLVILLVLALFN
What is the function of this protein?
In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.
What are the official names of this protein?
Circumsporozoite protein, CS.
What is the protein family that this protein belongs to?
Belongs to the plasmodium circumsporozoite protein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasm. Note=Localizes to the cytoplasm and the cell membrane in oocysts at day 6 post infection and then gradually distributes over the entire cell surface of the sporoblast and the budding sporozoites.