PharMolix/UniProtQA huggingface dataset:
Protein: FLIC_SALDE
Sequence: MAQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAAGADKYRVDINSGAVVTDAVAPNKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITGGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANATGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin, Phase 1-C flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: LOLA_PSEA8
Sequence: MRLIRTLFVAALAMGASLAHADDSAAVQRLTGLLNKAQTLTARFSQLTLDGSGTRLQETAGQLSLKRPGLFRWHTDAPNEQLLISNGEKVWLYDPDLEQVTIQKLDQRLTQTPALLLSGDISKISESFAITYKEGGNVVDFVLKPKTKDTLFDTLRLSFRSGKVNDMQMIDGVGQRTNILFFDVKMNEALDAKQFTFDVPPGVDVIQE
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CSEN_BOVIN
Sequence: MQRAKEVMKVSDGSLLGEPGRTPLSKKEGVKWQRPRLTRQALMRCCLVKWILSSAAPQGSYSSDSELELSAVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIRFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMSSMQLFENVI
What is the function of this protein?
Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS.  Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium.  Seems to be involved in nociception (By similarity).
What are the official names of this protein?
Calsenilin, A-type potassium channel modulatory protein 3, Kv channel-interacting protein 3, KChIP3.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor. Endoplasmic reticulum. Golgi apparatus. Nucleus. Note=Also membrane-bound, associated with the plasma membrane. In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus.
Protein: TP1A_RANJA
Sequence: ILPLVGNLLNDLL
What is the function of this protein?
Antibacterial activity against the Gram-negative bacterium E. coli and the Gram-positive bacterium S. aureus.
What are the official names of this protein?
Temporin-1Ja.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DYP_EXIGL
Sequence: MRLSPSFLSLALVIFVGEVVARNVVARASNPASVTGTRKVSLLKNVAGLPAVPTAQQVAVSSLNTDDIQGDILVGMHKQQQRFYFFTINDAATFKTHLAADIAPVVASVTQLSSVSTQPLVALNIAFSQTGLNALGVTDNVGDALFTAGQASNTVGNLKETTDNWVAQFKTPGIHGVILLASDDKSLIDQQEASIQSTFGAAISKVYSLDGAIRPGAEAGHEMFGFLDGIAQPAISGLGTPLPGQLVVDEGVIIVGGTNDPIARPADGWMTGGSFLAFRQLEQLVPEFNKYLLDNAPAVDGKSLQDRADLLGARMVGRWKSGAPIDLTPLADDPALGADPQRNNNFDFTHANFSITTDQTHCPFSAHIRKTRPRADLVAPANSIIRSGIPYGSEVSAAEAAANATTNERGLAFVSYQSQLNKGFQFLQNTWANNPGFIFGKNVQPGQDPIIGQNSGAIRSVVGLDPANPTGALSMGQFVVSRGGEYFFSPPISALTGKLAA
What is the function of this protein?
Manganese-independent peroxidase that is able to convert a large number of compounds, but its physiological substrate is not known.  In addition to classic peroxidase substrates (e. g.  2,6-dimethoxyphenol), oxidizes dyes such as Reactive Blue 5 and Reactive Black 5.
What are the official names of this protein?
Dye-decolorizing peroxidase, EglDyP.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBT_SORBI
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SHPS1_MOUSE
Sequence: MEPAGPAPGRLGPLLLCLLLSASCFCTGATGKELKVTQPEKSVSVAAGDSTVLNCTLTSLLPVGPIRWYRGVGPSRLLIYSFAGEYVPRIRNVSDTTKRNNMDFSIRISNVTPADAGIYYCVKFQKGSSEPDTEIQSGGGTEVYVLAKPSPPEVSGPADRGIPDQKVNFTCKSHGFSPRNITLKWFKDGQELHPLETTVNPSGKNVSYNISSTVRVVLNSMDVNSKVICEVAHITLDRSPLRGIANLSNFIRVSPTVKVTQQSPTSMNQVNLTCRAERFYPEDLQLIWLENGNVSRNDTPKNLTKNTDGTYNYTSLFLVNSSAHREDVVFTCQVKHDQQPAITRNHTVLGFAHSSDQGSMQTFPDNNATHNWNVFIGVGVACALLVVLLMAALYLLRIKQKKAKGSTSSTRLHEPEKNAREITQVQSLIQDTNDINDITYADLNLPKEKKPAPRAPEPNNHTEYASIETGKVPRPEDTLTYADLDMVHLSRAQPAPKPEPSFSEYASVQVQRK
What is the function of this protein?
Immunoglobulin-like cell surface receptor for CD47 (PubMed:18045614).  Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane.  Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment.  May play a key role in intracellular signaling during synaptogenesis and in synaptic function.  Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin.  Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation.  CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells (By similarity).  Plays a role in antiviral immunity and limits new world arenavirus infection by decreasing virus internalization (PubMed:30726215).  Receptor for THBS1 (By similarity).  Interaction with THBS1 stimulates phosphorylation of SIRPA (By similarity).  In response to THBS1, involved in ROS signaling in non-phagocytic cells, stimulating NADPH oxidase-derived ROS production (By similarity).
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Bit, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, MyD-1 antigen, Signal-regulatory protein alpha-1, Sirp-alpha-1, mSIRP-alpha1, p84.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: US12_HCMVA
Sequence: MVQIQFHQGEPLGHKKEKPPPVSPPSPPPIRRVTVITKDEDTLRSVQHFLWMVRLYGTVVFQTSATIATTILFMLIPWRVTAPYLRDTLPFWSTLLPCALRCHAYWLERRRRPGTLMLVMVYTTLTTISVSTIGLCFDRTVVIQAYVLSSMLCVWCTGLAWLMAWNMQRRLAILCLLSFMLPILWLFIAVQSWEPYQRIILALTVSFIYGLKIVLIRDTLTVLYRSPSNCYTDGDLLRTAMLLYMDQVIMFLLVVVPLTAPIWYPNYAGALGRTAHWLFHK
What are the official names of this protein?
Uncharacterized protein HVLF6.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US12 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: 3L2O2_OXYMI
Sequence: MKTLLLTLVVVTIVCLDLGYTRRCFTTPSVRSERCPPGQEVCYTKTWTDGHGGSRGKRVDLGCAATCPTPKKKDIKTICCSKDNCNTFPKWP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 3FTx-Oxy2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXA_METPB
Sequence: MASDDRPLALTLGDPSGIGPEIALAAWRLRGERGVPPFQLIGDPEFLEATAYRLGLSVPVAEVEPDDAVEVFARALPVLPLPSGAKVSATPGAPDSANAGAIVESITAAVDLVRSGAASAVVTNPIAKFVLTRVGFAHPGHTEFLAALAAREGREPPLPVMMLWSELLAVVPVTIHVALRRVPDLLTQELVERTARIVHADLRARFGLEAPRLVLSGLNPHAGESGTMGTEDRDVLAPAVAALRAEGIDIRGPLPADTLFHERARATYDVALAPTHDQALIPIKTLAFDEGVNVTLGLPFVRTSPDHGTAFDIAGKGVAKPDSLIAALRLAQRLAQRPANNVTPFPVRA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JZT4A_CHIGU
Sequence: MKNTSILFILGLALLLVLAFEVQVGESDGECGGFWWKCGSGKPACCPKYVCSPKWGLCNFPMP
What is the function of this protein?
Gating modifier of Kv2. 1/KCNB1, Kv2. 2/KCNB2 and Kv4. 3/KCND3 channels.
What are the official names of this protein?
Kappa-theraphotoxin-Cg3a 1, Kappa-TRTX-Cg3a, Jingzhaotoxin-4, JZTX-4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 44 (Jztx-4) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEC_PSEU2
Sequence: MSELTKTEKRAVILLSGGLDSATVVAMARAEGYVCYTMSFDYGQRHRAELDAAARVAGDLGAVEHKVIGLNLNGIGGSALTDSSIAVPESPSEGIPVTYVPARNTVFLSLALGWAEVLGARDIFIGVNAVDYSGYPDCRPEFVESFERMANLATKAGVEGQGFTIRAPLQNLSKSDIVKAGTALGVDYSLTVSCYQADDQGRACGKCDSCRLRAEGFTAAGIADPTRYF
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: LEUC_MYCSJ
Sequence: MAQPATPRTMAEKVWADHVVAHGTGEGAAREPDLIYIDLHLVHEVTSPQAFDGLRLANRPVRRPDLTIATEDHNVPTVDIDKPIADPVSRTQVETLRRNCAEFGIRLHPMGDAEQGIVHIIGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFRTMAVNVDGELPPGVSAKDIILAVIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMVAPDDTTFEFLRGRPHAPTGADWDAAVEAWRQLRTDPGAEFDTEVHLDAAELSPFVTWGTNPGQGVPLSGAVPDPELIVDEGERQAAEKALTYMGLQAGTAMRDVAVDTVFVGSCTNGRIEDLRVVADVLRGRRVADGIRMLVVPGSMRVRAQAESEGLDRIFIDAGAEWRQAGCSMCLGMNPDQLSPGQRCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSSPADLSAVPAR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: YD242_YEAST
Sequence: MNLEESQSNRGTLNIKKILVIVCMTNKICKHLIQSLLLSKRRLVSVLFDNYQGDMKLRSSPSAIPLVPSTKILQAMEARNDIVDSLIINSHATESDRRTLGDHEVRQCEDTNFGFKI
What are the official names of this protein?
Uncharacterized protein YDL242W.
Protein: CHS2_MAIZE
Sequence: MAGATVTVEEVRKAQRATGPATVLAIGTATPANCVYQADYPDYYFRITKSEHLTDLKEKFKRMCDKSMIRKRYMHLTEEFLAENPSMCAYMAPSLDARQDVVVVEVPKLGKAAAQKAIKEWGQPKSRITHLVFCTTSGVDMPGADYQLTKALGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAVVVGADPDDRVERPLFQLVSAAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIGRALDDAFKPLGISDWNSIFWVAHPGGPAILDQVEAKVGLDKARMRATRHVLSEYGNMSSACVLFILDEMRKRSAEDGQATTGEGLDWGVLFGFGPGLTVETVVLHSVPITTGAATA
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase C2, Naringenin-chalcone synthase C2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: PSTC1_MYCBO
Sequence: MLARAGEVGRAGPAIRWLGGIGAVIPLLALVLVLVVLVIEAMGAIRLNGLHFFTATEWNPGNTYGETVVTDGVAHPVGAYYGALPLIVGTLATSAIALIIAVPVSVGAALVIVERLPKRLAEAVGIVLELLAGIPSVVVGLWGAMTFGPFIAHHIAPVIAHNAPDVPVLNYLRGDPGNGEGMLVSGLVLAVMVVPIIATTTHDLFRQVPVLPREGAIALGMSNWECVRRVTLPWVSSGIVGAVVLGLGRALGETMAVAMVSGAVLGAMPANIYATMTTIAATIVSQLDSAMTDSTNFAVKTLAEVGLVLMVITLLTNVAARGMVRRVSRTALPVGRGI
What is the function of this protein?
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Phosphate transport system permease protein PstC 1.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASZ1_MICMU
Sequence: MASGGLRGLAVAGGGESSDSEDDGWEIGYLDRVSQKLKVPLPVEEKNETFKKALTTGDISLVQELLDSGISVDSSFRYGWTPLMYAASIANVELVRVLLDRGANASFDKDKQTILITACSARGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHPQVVAVLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKDGKIPSEIAKRNKHLEIFNFLSLTLNPLEGNLKQLTKEETICKLLTTDSDKEKDHIFSSYTAFGDLEIFLHGLGLEHMTDLLKEKDITLRHLLTMRKDEFTKNGITNKDQQKILSALKELEVEEIKFGELPEVAKLEISGDEFLNFLLKLNKQCGHLITAVQNIITELPVNSHKIVLEWASPRNFTSVCEELVSNVEDLSEEVHKLKDLIQKLQNERENDPTHIPLMEEVSTWNSRILKRTAIAVCGFGFLLFICKLTVQRKYPNICF
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: RL5_BACCR
Sequence: MNRLKEKFQKEITPALVSKFNYKSVMQVPKIEKIVINTGVGDAVSNSKALDNAVEELTQITGQKPVVTRAKKSIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSKKSFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTAKTDEEARELLTQFGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ISPG_THESQ
Sequence: MRKSVKVGNVVIGGGAPVSVQSMTTTKTADVERTISQIKRLERAGCEIIRVAVQDEEDAKAIRRIKEQIEIPLVADIQFDYRLAILSIDNGADKIRINPGNMSRDRLKDVVAAAKGKGIPIRVGANVGSIKRRTSERWKDLAESALEEVRLLEKEGFYDIVVSVKSSDILETIKANEYIAEKIEYPIHLGVTEAGVSETAVVKSSIAIGHLLLKNIGDTIRVSISGDPVREVIVGKKILIALGLREGVEVIACPTCGRAEIDVENMAKMIEENFFHVQKRLKIAVMGCVVNGIGEGKDADLGVAGLRDGAVIFVKGEIKERVSKEFVLERLKHYLNELLEEVER
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: 3SAA_NAJHA
Sequence: LECNQLIPIAHKTCPEGKNLCYKMFMVSTSTVPVKRGCIDVCPKNSALVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 10, Toxin CM-4a.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: NFUA_YERPG
Sequence: MITITDAAQSHFAKLLANQEEGTQIRVFVINPGTPTAECGVSYCPPDAVEATDTELKFEQLSAYVDELSVPYLQDAEIDFVTDQLGSQLTLKAPNAKMRKVDDSAPLMERVEYVLQSQINPQLAGHGGRVTLMEITPEGLAILQFGGGCNGCSMVDVTLKEGIEKELLQKFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: CCR5_SYMSY
Sequence: MDYQVSSPTYDIDYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKHFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BCD1_HUMAN
Sequence: MEFAAENEGKSGGGLHSVAEGVRLSPEPGREGVRDLAGAEEFGGGEEGTGLTGIKEIGDGEEGSGQRPEEIPMDLTVVKQEIIDWPGTEGRLAGQWVEQEVEDRPEVKDENAGVLEVKQETDSSLVVKEAKVGEPEVKEEKVKEEVMDWSEVKEEKDNLEIKQEEKFVGQCIKEELMHGECVKEEKDFLKKEIVDDTKVKEEPPINHPVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKKHKAELTCNGVRDKTAYISIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRPISNKYMYFMKNRARRQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAEYIEKRVPDDKTINEILKPYIDPEKSDPVIRQRLKAYIRSQTGVQILMKIEYMQQNLVRYYELDPYKSLLDNLRNKVIIEYPTLHVVLKGSNNDMKVLHQVKSESTKNVGNEN
What is the function of this protein?
Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
What are the official names of this protein?
Box C/D snoRNA protein 1, Serologically defined breast cancer antigen NY-BR-75, Zinc finger HIT domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the BCD1 family.
Protein: RSMB_YEAST
Sequence: MSKIQVAHSSRLANLIDYKLRVLTQDGRVYIGQLMAFDKHMNLVLNECIEERVPKTQLDKLRPRKDSKDGTTLNIKVEKRVLGLTILRGEQILSTVVEDKPLLSKKERLVRDKKEKKQAQKQTKLRKEKEKKPGKIAKPNTANAKHTSSNSREIAQPSSSRYNGGNDNIGANRSRFNNEAPPQTRKFQPPPGFKRK
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
What are the official names of this protein?
Small nuclear ribonucleoprotein-associated protein B, snRNP-B, Sm protein B, Sm-B, SmB.
What is the protein family that this protein belongs to?
Belongs to the snRNP SmB/SmN family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: KIF3C_BOVIN
Sequence: MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAALGELPKTFTFDAVYDASSKQADLYDETVRPLVDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPEQRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLVSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFVITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKAGPNTTGGTATQPTGGGGGGGGGGGGGERPKEASKINLSLSALGNVIAALSGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKKGMLGKRLRRKSSRRKKAVSAPAGYPEGPVIEAWVAEEEDDNNNNHRPPQPILETALDKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKKKLLEEKEKMLEDLRREQEATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQPLVPSGANSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPAVFEMEFSHDQDQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPQRPPPPTAHASLAASAALRPTTVLDHE
What is the function of this protein?
Microtubule-based anterograde translocator for membranous organelles.
What are the official names of this protein?
Kinesin-like protein KIF3C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RPOA_PROMA
Sequence: MLQYQIDRIEHQVSDDRSQTGIFLIGPLERGQATTLGNSLRRVLMGGLEGSAVTAVRISGVNHEYATVPGVREDVLDILLNCKELTVNSRSQELEIGRLVVTGPAEVKARDLQFSSQVQIVDVDRPIATVHSGHSLELELHVERGVGYRPVDRRNEATTAIDLLQIDAVFMPVKKVNFTIDETAVSEGGSTRERLRMEIVTDGSITPDDAVAEAANQLIELFQPLATVTMVEEVPQEPEPTAEAQIPLEELNLSVRAYNCLKRAQVNSVSDLMGFSYEDLLEIKNFGSKSADEVIEALERIGISIPQSRTSA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RUVA_MYCAP
Sequence: MILYRIGEIIHKHNSNIIFESQGIGYSLILPDPERVEIKQKCKLYLFEIKNEYQYATYAFKDFKERLLFVDLISLNGIGPRAAFNILNFGFEKVVALIAEGNAEALIEIPYLNPRMARLIVAELQAKWSKMISPKDAAKINETTNTLSEVKETLKMVGFKTKQIDGALSKISSTDDVEKMIEEAIKLMSTQNYESATA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.