PharMolix/UniProtQA huggingface dataset:
Protein: SGSM1_HUMAN
Sequence: MASAPAEAETRQRLLRTVKKEVKQIMEEAVTRKFVHEDSSHIISFCAAVEACVLHGLRRRAAGFLRSNKIAALFMKVGKNFPPAEDLSRKVQDLEQLIESARNQIQGLQENVRKLPKLPNLSPLAIKHLWIRTALFEKVLDKIVHYLVENSSKYYEKEALLMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHVRQDSPTKRPALCIQKRHSSGSMDDRPSLSARDYVESLHQNSRATLLYGKNNVLVQPRDDMEAVPGYLSLHQTADVMTLKWTPNQLMNGSVGDLDYEKSVYWDYAMTIRLEEIVYLHCHQQVDSGGTVVLVSQDGIQRPPFRFPKGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPKLRKRSPQGSAESTSSDKDDDEATDYVFRIIYPGMQSEFVAPDFLGSTSSVSVGPAWMMVPAGRSMLVVARGSQWEPARWDTTLPTPSPKEQPPMPQDLMDVSVSNLPSLWQPSPRKSSCSSCSQSGSADGSSTNGCNHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLSTVRTHLSALVNHMIVSPDLPCDAGQGLTARIWEQYLHDSTSYEEQELLRLIYYGGIQPEIRKAVWPFLLGHYQFGMTETERKEVDEQIHACYAQTMAEWLGCEAIVRQRERESHAAALAKCSSGASLDSHLHRMLHRDSTISNESSQSCSSGRQNIRLHSDSSSSTQVFESVDEVEQVEAEGRLEEKQPKIPNGNLVNGTCSPDSGHPSSHNFSSGLSEHSEPSLSTEDSVLDAQRNTPTVLRPRDGSVDDRQSSEATTSQDEAPREELAVQDSLESDLLANESMDEFMSITGSLDMALPEKDDVVMEGWRSSETEKHGQADSEDNLSEEPEMESLFPALASLAVTTSANEVSPVSSSGVTYSPELLDLYTVNLHRIEKDVQRCDRNYWYFTPANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFLVWETIWAAKHVSSAHYVLFIALALVEVYRDIILENNMDFTDIIKFFNEMAERHNTKQVLKLARDLVYKVQTLIENK
What is the function of this protein?
Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others.  Promotes GTP hydrolysis by RAB34 and RAB36.  Probably functions as GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B.
What are the official names of this protein?
Small G protein signaling modulator 1, RUN and TBC1 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the RUTBC family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm. Note=Recruited to cytoplasmic vesicle membranes via its interaction with Rab family members, such as RAB9A.
Protein: IBB_VICFA
Sequence: GDDVKSACCDTCLCTKSEPPTCRCVDVGERCHSACNSCVCRYSNPPKCQCFDTHKFCYKSCHN
What is the function of this protein?
This inhibitor has two domains, each with separate antiprotease activity.  Inhibits bovine trypsin and chymotrypsin, in a molar ratio of 1:1.  The trypsin inhibition of FBI is independent of chymotrypsin inhibition, but the chymotrypsin inhibition is not completely independent of trypsin inhibition.
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor, FBI.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: OTAR1_ASPNC
Sequence: MDGFEIASELLQASHHLPVLGTGSPSGSDIISGNYMLGYSADDANLSQFEQLEGLLGSPTVANHVDFGKETADLAFLDDSGGILSSVELAGMVSPPLDAVVPMPGITRASRSRPAFSTPASRPGLSSAKSPSLGATSPGSMDRSEEVKQLRKKYHEKYKERNRLAAGRSRQKQADLINLLQAEQQEEERRRKALELEIANMQKELVDMKQELQHHIRISNC
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of ochratoxin A (OTA), a mycotoxin demonstrated to have nephrotoxic, immunotoxic, genotoxic, neurotoxic, and teratogenic properties (PubMed:27667988, PubMed:33391201).  Positively regulates the expression of the OTA biosynthetic genes and subsequent production of OTA (PubMed:35143724).  Probably binds to conserved 5'-ACGT-3' bZIP binding motifs found in multiple copies (3 to 4) in the promoters of the OTA biosynthetic genes (PubMed:35143724).  Acts not only as a pathway-specific regulator of the OTA cluster but binds also at other chromosomal positions outside the OTA cluster and can act as a broad regulator (PubMed:35143724).  Negatively regulates pathogenicity and plays a critical role in tolerance to reactive oxygen species (ROS) (PubMed:35143724).
What are the official names of this protein?
Transcription factor otaR1, Ochratoxin biosynthesis cluster bZIP transcription factor, Ochratoxin biosynthesis cluster protein 4, Ochratoxin biosynthesis cluster protein R1.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADK_METST
Sequence: MRIGIISRTDKEEAIELDDTIIKYLFENNIEVELDSQLTKKLPQYSENSVDITKMNADIVLCVGGDGTVLHAQRYLSPKKIPILSINMGTVGFLTEVDPEDIFECLDKLLSYDFFIEERLQLDVLIDSQWHTVLNELVLMTSQPAKMLDLRVSVDEEIVDEVRADGLIISTPSGSTAYAMSAGGPIVDPRVDAAIIIPICPFKLNTRPKIVPADSIITVKFLKEGKKGVAVLDGIVNKEFDYLGEIKLKKSENSAYFVRFKKNFYNSVNNKLIVG
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS1_FRIAG
Sequence: MAASSTMLSSVATAACAAPAQASMVAPFVGLKSTSAFPVTQKPATGLSTLPSNGGRVQCMKVWPIVGLKKFETLSYLPTLSVESLLKQIEYLIRNGWVPCLEFSLEGFVSRDNNKSPGYYDGRYWTMWKLPMFGCTDAAQVVKEAAECKKEYPAAFIRVIGFDNVRQVQCVSFIVERPE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 1/4, RuBisCO small subunit 1/4.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CEL3A_MAGO7
Sequence: MASRLVAGLQVLALAGTATAVLTWDEAYAKANTALARITQQDKVSLVSGIGWDKGPCVGNTAPVSAINYPQLCLQDGPTGVRFGTGVTAFTPGIQAASTWDVELMRQRGQFQAEEQKGCGVHVMLTPVAGALGKIPEGGRNWEGFGVDPYLAGIAMEVTIEGQQSVGVQATAKHYLLNEQELNRNTMSSNVDDRTLHELYLWPFADAVRANVASVMCSYNKINGSWACENEHAMQKLLKDELGFKGYVMSDWNAQHTTTGSANAGMDMTMPGSDFNGGNVLWGPQLNTAVNNNQVARTRLDDMARRVLAAWYLTEQDKGYPPINIRANVQGNHKENVRAVARDGIVLLKNDAGALPFKAPRRLAIVGSASVANPRGINSCVDRGCNEGALGMGWGSGTTNYPYFSAPADAIRARAQQDGATVTLSASDSTADVANTVRDADAAIVFLTSNSGEGYLLVDGSYGDRLNLDPLHNGNQLVQAVAQANKNTIVVVHSVGPLVLESILSTPGVTAVVWAGLPGQESGNALVDVLYGSVSPSGKLPYTIARATADYGTAIVPGDDNFPEGLFVDYRHFDRANIQPRFEFGYGLSYTNFTYSNIKVASTVRSGPATGPVVSGGRADLWETVATVTATVTNSGGVAGAEVAQLYVSYPKGGSVPETPPRQLRGFNKLKLAPGASGTATFNIRRRDLSYWHVGQQNWVVPAGAFGLEVGASSRDLRLKESITVV
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose.  Has a broad substrate specificity but preferentially hydrolyzes highly polymerized 1,3- and 1,4-beta-glucans.
What are the official names of this protein?
Beta-glucosidase cel3A, Beta-D-glucoside glucohydrolase cel3A, Cellobiase cel3A, Gentiobiase cel3A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLO2_ENCCU
Sequence: MGIEVISILVGGGNNYMHLFYDDDAAFCVDASNPRILLKALGINFKKSIYDEKEIFSMGEDRKKRRELVYLFTTHKHLDHSAGIRCISEESPNTKTISGFSGDICKSGDKFRFKDVEIECFHTPCHTVDSFCFYVGEKYLATGDTLLFLGCGKFFGGTPGQMIKNIEEIKKRVNHDAVLLYGHDYSEQNIRFTEEFYHVPEEIKKKKFLKLAEEIKYNPFFNLKKVSIEGSEEEVMGKLRERKNKFSKE
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Probable hydroxyacylglutathione hydrolase ECU02_0580, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLGB_BACCL
Sequence: MIAANPTDLEVYLFHEGRLYQSYELFGAHVIRGGGAVGTRFCVWAPHAREVRLVGSFNDWNGTNSPLTKVNDEGVWTIVVPENLEGHLYKYEIITPDGRVLLKADPYAFYSELRPHTASIVYDLKGYEWNDSPWQRKKRRKRIYDQPMVIYELHFGSWKKKPDGRFYTYREMADELIPYVLERGFTHIELLPLVEHPLDRSWGYQGTGYYSVTSRYGTPHDFMYFVDRCHQAGLGVIIDWVPGHFCKDAHGLYMFDGAPTYEYANEKDRENYVWGTANFDLGKPEVRSFLISNALFWLEYYHVDGFRVDAVANMLYWPNNDRLYENPYAVEFLRQLNEAVFAYDPNVWMIAEDSTDWPRVTAPTYDGGLGFNYKWNMGWMNDMLKYMETPPHERKYAHNQVSFSLLYAYSENFILPFSHDEVVHGKKSLLNKMPGSYEEKFAQLRLLYGYMMAHPGKKLLFMGSEFAQFDEWKFAEELDWVLFDFELHRKMDEYVKQLIACYKRYKPFYELDHDPRGFEWIDVHNAEQSIFSFIRRGKKEGDVLVIVCNFTNQAYDDYKVSVPLLAPYREVLNSDAAEFGGSGHVNGKRLPAFSEPFHGKPYHVRMTIPPFGISILRPVQKRGERKQNEEEVHRHVIGRRARKPASLADEKHRETSRAVWGEVPDH
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: UPPP_STRP7
Sequence: MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNEAFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGVFKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYIGLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKAGELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSFVRLFV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIOB_MYCUA
Sequence: MVTQAATRPSNDAGQDGVTEPDILAVARQQVLERGEGLNQEQVLQVLQLSEDRLEELLVLAHDVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFSSPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDARLLSQVAAGIEAIRNEVEINVACSLGMLTAEQVEQLAAMGVHRYNHNLETARSYFTNVVTTHTWEERWQTLTMVRDAGMEVCCGGILGMGETLEQRAEFAANLAELDPDEVPLNFLNPRPGTPFGDLEVLPAGEALKAVGAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLEDLQMPLKALNASL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: Y2133_DESVH
Sequence: MAENESNVVVDQGQTKLSDLWTKEDYWAIWLGFVILIAGMWLFLANPSPEFAQKVDKANGVMAAEAARAPFKTLAYYKAQDDKGKLQGMDTPSGKAIGAFLTTPGAWASDPLEAFVLSKEAADERNAAAKAKFESAKVKSDAALAAAQAAEAAAAGAAFADAALNTEAQAKIAEWRAEHAKMKAAEKKTKTKPFNIATSLPMLMVALGLFFAVGMKFMGHDVPKFLVGFIGVFFVAVLALMMGHQSTMKYWGIGAEAWAIIIGMLVANTVGTPSFIKPALQVEYYIKTGLVLLGAEVLFDKIIAIGIPGIFVAWVVTPIVLICTFIFGQKILKMPSKTLNIVISSDMSVCGTSAAIATAAACRAKKEELTLAIGLSLVFTAIMMIAMPAFIKAVGMPQVLGGAWMGGTIDATGAVAAAGAFLGEKALYVAATIKMIQNVLIGVVAFGVAVYWCARVECREGHSVGWIEIWHRFPKFVLGFLAASVLFSVISGSLGSDMSQIMVNQGVLKGLSSPLRNWFFCLAFTSIGLATNFRELAHYFKGGKPLILYVAGQSFNLVLTLAMAYVMFYIVFPEITAKI
What are the official names of this protein?
UPF0324 membrane protein DVU_2133.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PA_I49A1
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTRVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLLAWKQVLAELQYIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFEDCKNISDLKQYDSDEPEQRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFVIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPYKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAQSSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: TBPL1_DANRE
Sequence: MEPSNDVALDIIVTNVVSVFRTRCHLNLRTIGLEGTNVIYKPEVGKVLMKLRKPRITASIWSSGKIICTGATSEEEAKLGARRLARCLQKMGFKVRFSDFKVVNVLAVCSMPFQIRLIEFTKNNRPIASYEPELHPAASYRIKNLRSTVQVFSTGNITVTGPNVQSVASAVEEIYPLLFECRKTLS
What is the function of this protein?
Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes.  Seems to also mediate the transcription of NF1.  Does not bind the TATA box (By similarity).  Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis.
What are the official names of this protein?
TATA box-binding protein-like 1, TBP-like 1, TATA box-binding protein-related factor 2, TBP-related factor 2, TBP-like factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NU3M_PERBO
Sequence: MNMLTALSVNIALSTCLIAIAFWLPQLNLYTEKANPYECGFDPMSSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQTNNINTMMLTAFILVSVLALGLAYEWMQKGLEWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS18_OENOB
Sequence: MAEEHSNQRSQTFNGERTNRPSRKPRGDGERRGRRQGGRRRVDYLAVNHIDYVDYKDTELLQRFIADNGKILPRRITGTSSKNQRKIATAIKRARIMALLPFVANN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MDM10_ASPTN
Sequence: MLDFMEYIQLGFAEATNWNRDNSYSSLTATAQSLLDFKTPERLRVHLSSLSTPHFATSYTLGTVGLIDGSVSYLYSTVPFDHTPSRSALIPLRKLAPGYRQVQPPVAPIENWGWDSTLNHETTPLAQKATLLHATMHMPPPTTLNALFLRRISPTMQLTLAVCSTRGPPLSKSAPQASLLTQLSHDTGKYSNEYLFSTDNALFGWRGLWNFGPDPRNPADDAAPRLSLLSAGAEAYYSPVSSLVGMSTGLRFSTLPAATDASSAPSSSSSPSSATPTQISTFPYTLTLTLTPMTGSLSTTYSLRASPNLSFSSRFGFNVYSWESEMVAGCELWRQSRKRVPAEEEDDGLEWARRKLRMMDDAAVPLPPTSSVPAEPEQDETTESVLKIRVDQSWNVRLLWEGRVKELLVSAGVGLGPSSFSSSAWTNSTAGGAGGQASGGGNAGTSYWRGVGVSVSYSS
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component mdm10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: MDH_VIBVU
Sequence: MKVAVIGAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAADLSHIPTHVSIKGYAGEDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGIVKSLAERIAVVCPNACIGIITNPVNTTVPIAAEVLKKAGVYDKRKLFGVTTLDVIRSETFVAELKGQDPGEVRVPVIGGHSGVTILPLLSQVEGVEFSDEEIAALTKRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLALVKALQGEEVIEYAYVEGNGEHASFFAQPVKLGKEGVEEILPYGELSDFEKAALDGMLETLNSDIQIGVDFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: RS121_ARATH
Sequence: MSGDEAAPVVVPPPVAEPAAIPEDMDLMTALELTLRKARAYGGVVRGLHECAKLIEKRVAQLVVLAEDCNQPDYVKLVKALCADHEVRLLTVPSAKTLGEWAGLCKIDSEGNARKVVGCSCLVVKDFGEETTALSIVNKHIASQ
What are the official names of this protein?
40S ribosomal protein S12-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS12 family.
Protein: PSA_MYCA9
Sequence: MTFPYYASVEQLMRDRSELARKGISRGRSVVALTYTDGVLFVAENPSNSLQKVSEVYDRVGFAAVGKFNEFDRLRRGGIQWADMRGYAYDRRDVSGRQLANIYAEALGTIFNEQAKPYEVELCVGEVAHYGRDTEPVLYRITYDGSIADEPHWVVMGGNTEPVINSLKESYVEDSALKDAVGFAVKALQAGTAGANGSEGRALGGLEVAVLEQSRPRRAFRRIKGAALEALLPEDFSPGQTEGGGDPAPESGDSKDAKDN
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSHB_MELGA
Sequence: MGGAQVLVLMTLLGTPPVTTGTPPVVVDPSVAVVGPPLGLGGGGRPPCRPINVTVAVEKDECPQCMAVTTTACGGYCRTREPVYRSPLGRPPQSSCTYGALRYERWALWGCPIGSDPRVLLPVALSCRCARCPIATSDCTVQGLGPAFCGAPGGFGIGE
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin subunit beta, Lutropin beta chain, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL33_CAMJD
Sequence: MRIKVGLKCEECGDINYSTYKNSKNTTEKLELKKYCPRLKKHTFHKEVKLKS
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PRLHR_MOUSE
Sequence: MTSLSTETTGDPDLSSGLLPASSTPANQSAEASEGNLSATVPRAAAVTPFQSLQLVHQLKGLIVMLYSIVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCAACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIALDRYVVLVHPLRRRISLRLSAYAVLGIWALSAVLALPAAVHTYHVELKPHDVSLCEEFWGSQERQRQIYAWGLLLGTYLLPLLAILLSYVRVSVKLRNRVVPGSVTQSQADWDRARRRRTFCLLVVVVVVFAVCWLPLHIFNLLRDLDPRAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKMLLSWPRKIVPHGQNMTVSVVI
What is the function of this protein?
Receptor for prolactin-releasing peptide (PrRP).  Implicated in lactation, regulation of food intake and pain-signal processing.
What are the official names of this protein?
Prolactin-releasing peptide receptor, PrRP receptor, PrRPR, G-protein coupled receptor 10.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 10HGO_CATRO
Sequence: MAKSPEVEHPVKAFGWAARDTSGHLSPFHFSRRATGEHDVQFKVLYCGICHSDLHMIKNEWGFTKYPIVPGHEIVGIVTEVGSKVEKFKVGDKVGVGCLVGSCRKCDMCTKDLENYCPGQILTYSATYTDGTTTYGGYSDLMVADEHFVIRWPENLPMDIGAPLLCAGITTYSPLRYFGLDKPGTHVGVVGLGGLGHVAVKFAKAFGAKVTVISTSESKKQEALEKLGADSFLVSRDPEQMKAAAASLDGIIDTVSAIHPIMPLLSILKSHGKLILVGAPEKPLELPSFPLIAGRKIIAGSAIGGLKETQEMIDFAAKHNVLPDVELVSMDYVNTAMERLLKADVKYRFVIDVANTLKSA
What is the function of this protein?
Dehydrogenase involved in the biosynthesis of oxogeranial from hydroxygeraniol, a precursor of the terpenoid indole alkaloids such as vinblastine and vincristine.
What are the official names of this protein?
8-hydroxygeraniol dehydrogenase, Cr10HGO.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RS3_STAAN
Sequence: MGQKINPIGLRVGIIRDWEAKWYAEKDFASLLHEDLKIRKFIDNELKEASVSHVEIERAANRINIAIHTGKPGMVIGKGGSEIEKLRNKLNALTDKKVHINVIEIKKVDLDARLVAENIARQLENRASFRRVQKQAITRAMKLGAKGIKTQVSGRLGGADIARAEQYSEGTVPLHTLRADIDYAHAEADTTYGKLGVKVWIYRGEVLPTKNTSGGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL5_DESHD
Sequence: MARLKDKFSSEIAPALQQKFNYKNVMQIPKLEKVVINVGVGEAIQNSKAIDAAVGDLSKITGQKPVVTRAKKSIAAFKLRTGMPIGTKVTLRGDRMYEFVDRLMNVALPRVRDFHGVSDKAFDGRGNYTLGIKEQLIFPEIEYDKIDKVRGMDIIFVTTAKTDEEARELLGMLGMPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.