PharMolix/UniProtQA huggingface dataset:
Protein: SYV_MESH2
Sequence: MKNKYDFKLVEEKRNEKWQKKGFFIAPKQTKKPFSIISPPPNVTGQLHLGHSWNAFIQDSLVRYHKLQGFDVLLLPSVDHAGIATQVKVEEDLAKKGIKKSDLKREEFIKKCYHWKEKQYLKIKEQWDKLGICYDFSKERFTLDQDAQIAVSDFFIKLWEKNLIYRGQKAINWDIKLQTAISNIEVINKPVEQKMYYLKYFLENSNEFLTVATTRIETISSDVALAINPKDKRYLHLVGKKVVHPLTKKLIKIIADSNVGSDFGSGIMKVSAHSILDFEIMEKHNLESKDCIDNYGNLNHEVPEFQGQNRFFARDLIAKKLEKEGFLAKIETVISNVGFSQRSDEIVEILKKPQWFVKMDELAKSLISHLNSKDKIKFYPKNFEKNLRKWFEKIHDWTISRQLWWGHRIPVWYKNDEFKVQIDSPGQGWIQDEDVLDTWFSSGISVFAFLGWPQNFDLIKSYFPTSLLVTGWDILFFWVARMYFSSLFIMKQKPFEKVLLHGLIRDEIGRKMSKSLGNGLDPMEIIEKYGSDTLRQALIFNSSPGKDIKFNIEKLNTAWNLNNKIWNIAKYIADLDTFFAKPDLIDLWMENKIYILKRQIVKNIKKYNFSVIGTEINNFIYGDFSSRYIELIKTRKNGFYARKLLRKVLIILHPFLPFLTDFLMEKIFKMEILEQKMPRIRQFKENQKVENILEIIDNLRTYREKFQISKKIILEYCIINDKFSNAEIDIINKLTFGKWLENKELVIKTKNFEIAIKVPEELKKEQKGRELKEIQFLKSEILRAEKILTNKGFLEKAPREKIDLERTKLEKLKEKLAFYEKK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTO_ENTHI
Sequence: DAKALAGIADAKLKHTETGDKSAPVIENVEIKKGDRNELLSGIKEGKELKKAETNDRSAPVIPADAKVQEDNRGALLADIQATAK
What is the function of this protein?
Is able to bind two actin monomers at high concentrations of G-actin.
What are the official names of this protein?
Actobindin homolog.
Protein: RL1_STAA9
Sequence: MAKKGKKYQEAASKVDRTQHYSVEEAIKLAKETSIANFDASVEVAFRLGIDTRKNDQQIRGAVVLPNGTGKSQSVLVFAKGDKIAEAEAAGADYVGEAEYVQKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVKKAVEEIKAGKVEYRAEKAGIVHASIGKVSFTDEQLIENFNTLQDVLAKAKPSSAKGTYFKSVAVTTTMGPGVKIDTASFK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YIDC_RICAH
Sequence: MNNNIINLIAAIVLSLSIIFGWQYFVIKPEQKKQQQQIAVQKAANLKKQQLKALVEPATDIVVQEESQVQRIKIESESLTGSISLKGLRFDDLILKKYKQDLSKNSSDVVLFSPTNTEHSYFAEIGLVSNLSSVKLPNNDTIWSSDGEILSPEKPVNLFWVNEDGVKFLVTITVDKNYLFTIEQTIVNNSDKELPIQSYGLINRKYTAVEKAVNILHQGPIGCIDENLKEYSYDDIKDKKSEKFAASKVDWIGITDKYWLSALIPDKSSNYSSNFNYAVKQGIEKYQVDFISPVQIIKPGENFAIKSRIFAGAKKVDLLDQYEKQYDIKLFDRAIDFGWFYIITKPVFYAMNFFYGYVGNFGVSILIVTVIIKLLMFTLANKSYRSMKKIKNLQPEIDRIKNLYSDDKARLNQEIMALYKKEKVNPVAGCLPILVQIPVFFSIYKVLYVTIEMRQAQFYGWIKDLSAPDPTTIFNLFGLLPFSPPSFLMIGAWPILMAITMFLQQKMSPEPADPMQAQVMKFMPLIFLFMFSSFPVGLLIYWSWNNILSIIQQYYINKFN
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NCPP_SALDC
Sequence: MHQVISATTNPAKIQAILQAFEEIFGEGSCHITPVAVESGVPEQPFGSEETRAGARNRVDNARRLHPQADFWVAIEAGIDDDATFSWVVIDNGVQRGEARSATLPLPAVILDRVRQGEALGPVMSHYTGIDEIGRKEGAIGVFTAGKLTRSSVYYQAVILALSPFHNAVYR
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: M200_ARATH
Sequence: MLNAFAFPQTNECFPAKRGFCANERTKCLNPKMPSKSMFGGSVSENLFLSKIRIGLSFPLPLSEIKLQNQDFRLEGQMSSFDPFVDESKALVRRLGQKVKAKSFLCR
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00200, ORF107B.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DUS4_SCHPO
Sequence: MRDRLKDPVKIFEINKGKRPVHIAAPMVRYSKLPFRQLVRDYNTDIVYTPMILAKEFLHPKGRYFDFSTNDADASLILQFGVDDPVILEKAAQLVGPYVDGIGINCGCPQTWAIQEGIGSALLDEPEKVHKLVRAVKSTLGESFCTEVKIRIAKDLNKTRHLMQVIEKSGADIITVHGRTRQDRSSFPVNLDAIREVRPCVQIPVVANGDVKSLRKGLEIAKYTETQGIMSARGLLENPALFAGYEETPWGCVERFLWYSTSYSLNFHLFYHHLTTMMGQMTTKRERMTIPKDSFASVMDWLDEHFVVRRPDEPMFGESVLPCRRY
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:34798057).  Also able to mediate dihydrouridylation of some mRNAs, thereby affecting their translation (PubMed:34798057).
What are the official names of this protein?
tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+], mRNA-dihydrouridine synthase dus4, tRNA-dihydrouridine synthase 4.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus4 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ACPS_GLOVI
Sequence: MAGQTFLHRIGTDLVHIPRIEGMLERYGKQFLNRVYTEGEQHYCLASKPHRANRLAGRWAAKEAVTKALGTGWRGVGYRDIEVVRLASGEPTICLNGRAVLLVERFGRLDWQVSFSHDREYAVATVSVIGFF
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SER33_YEAST
Sequence: MSYSAADNLQDSFQRAMNFSGSPGAVSTSPTQSFMNTLPRRVSITKQPKALKPFSTGDMNILLLENVNATAIKIFKDQGYQVEFHKSSLPEDELIEKIKDVHAIGIRSKTRLTEKILQHARNLVCIGCFCIGTNQVDLKYAASKGIAVFNSPFSNSRSVAELVIGEIISLARQLGDRSIELHTGTWNKVAARCWEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYDIVTIMALGTARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIEVATALSKYINEGNSVGSVNFPEVSLKSLDYDQENTVRVLYIHRNVPGVLKTVNDILSDHNIEKQFSDSHGEIAYLMADISSVNQSEIKDIYEKLNQTSAKVSIRLLY
What is the function of this protein?
Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway.  Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
What are the official names of this protein?
D-3-phosphoglycerate dehydrogenase 2, 3-PGDH 2, 2-oxoglutarate reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: HIS6_NEIG1
Sequence: MALAKRIIPCLDVKDGRVVKGVNFIGLRDAGDPVEAAKRYNGEGADELTFLDITASSDNRDTILHIIEEVAGQVFIPLTVGGGVRTVADIRRLLNAGADKVSINTAAVTRPDLINEAAGFFGSQAIVAAVDAKAVNPENTRWEIFTHGGRNPTGLDAVEWAVEMQKRGAGEILLTGMDRDGTKQGFNLPLTRAVAEAVDIPVIASGGVGNVRHLIEGITEGKADAVLAAGIFHFGEIAIREAKRTMREAGIEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_AGGAC
Sequence: MAKQDYYELLGISRSADEKEIKRAYKKLAMQYHPDRTKGDKEKEEKFKEIQEAYEVLNDKEKRAAYDQYGHAAFEQGTGFGGGSFGGADFGDIFGDMFGDIFGGGGRGRQRVVRGDDLRYDIEITLEEAVKGTTKDIKIHTLAPCDTCHGTGAEAGSKVETCPHCHGAGRLRRQQGFFVTEQPCHFCHGTGKKIEKPCKTCHGDGRVNKAKNLSVKIPAGVDTGNQLRLSGEGAAGENGAPAGDLYVVIHVKEHHIFERDGSNLYCEVPISFTMAALGGEIEVPTLDGRVKLKIPEETQTGKLFRMRGKGVTSTRSGYAGDLTCRIIVETPVKLNEEQKELLRKLEESLEGQTKQRPKSSSFLDGVKRFFDDLTK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VME1_PEDVB
Sequence: MSNGSIPVDEVIEHLRNWNFTWNIILTILLVVLQYGHYKYSVFLYGVKMAILWILWPLVLALSLFDAWASFQVNWVFFAFSILMACITLMLWIMYFVNSIRLWRRTHSWWSFNPETDALLTTSVMGRQVCIPVLGAPTGVTLTLLSGTLLVEGYKVATGVQVSQLPNFVTVAKATTTIVYGRVGRSVNASSGTGWAFYVRSKHGDYSAVSNPSAVLTDSEKVPHLV
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: FOLD_CHLL3
Sequence: MLIIDGKKVSLDMKEELKASVESYRSITGKVPGLTVIIVGSDPASEVYVRNKAKTCKEVGMNSSVIELQEDTPEAHLLEVIDSLNRDPAVHGILVQQPLPKQIDEFAVTLAIDPAKDVDGFHPENLGRLVMGHLDKCFVSCTPYGILELIGRYGIETSGKHCVVIGRSNIVGKPMANLMMQKLKESNCTVTVCHSATKDIASYTRQADILIAAIGRAKFVTADMVKQGAVVIDVGINRIEDPTTKSGTRLVGDVDYEGVSAKAAAMTPVPGGVGPMTIAMLLKNTLHSFERANGL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RS6_HELPJ
Sequence: MRHYETMFILKPTLVEEEIKSKIEFYREVITKHHGVIETSLDMGMRNLAYEIKKHKRGYYYVAYFKADPSMILELERLYRINEDVLRFIVIKYESKKEVEAWHALVDRANKKPSHAKEKHEKTEHTHSHHAEEAKSTESHSE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: HIS6_ALBFT
Sequence: MLAKRIIPCLDVTGGRVVKGVNFVELRDAGDPVEIAARYNDQGADELTFLDITATSDGRDLILHIIEAVASQVFIPLTVGGGVRTVDDVRRLLNAGADKTSFNSAAIANPQVIRDASRKYGAQCIVVAIDAKRRLATDVGRLDANGQAVGEGWDVYSHGGRKNTGLDAVIWARLMAELGAGEILLTSMDRDGTKAGFDLALTRAVSDAVSVPVIASGGVGTLDHLADGIQIGGADAVLAASIFHYGEFTVAQAKAHMAARGIPVRI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_BRUSU
Sequence: MKSAVILLPGLNRDRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRCGAIAARMPVMQAVREKADKGVMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEGEGQVVFRYAEGTNPNGSVNDIAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX6_PICPA
Sequence: MPGITETSQVTGPVLAHVIVTEDPYDASERAFLSTDLYELLFEDYANGSKSGLTLISIQLMGSSLFNEFQTFKVYESEEQLPPNTVNLCNMGNIIDYSSDFTVDSGYVARVDSLVKLDTVIISVLPEVYSLASQSQHQLVDILGGNDQHTVIRQGDYNKDINGKISLCEPTDQGFLESTTKIIVVKENSLNLPLLDQSQDGSLNYEENVKMNLEHSISNYFSLNSLDPENQITTTGVEFSVKCLDSPISVRKTAKSISVAHDSEDESSPKLVEEDISNEDTLLYAFCKTTELAKIGCLSGDIVKMKSGQCQCTTFECNCESCPVQYRYIRIHAFTDPNTYEKGCIYLNPILSFNLNNPKIVKLCPISIPDKRFELQGFHFSKFIPLAKQVTIARVSSPVTLDRTLQTLFLTNLKTYFESGRKVLSKDQLIPIPVDTLLAKSIFSTYEKLGVDDSQFPTVIPEGKPDAIAWFKVTEVSGELADSASQQFIIDPLKTKMMQSGVVSCSPPKNSQHCNWANYLGCGQMFSFPNVSGVTTSTFEYAKTLRKLIKATIDPSRLVNLQTTVLLSSLSRAIGKSLLVHSLALECGVHLVEIDGYEVLNPSSESKTIGTIRGKLDRVVEGCTPLIVFIKHIEALTKKSEQQQKDSLAVKINELIDEYTAKPGVLFVASTNDSDNLSDELRAKFKFEIVLGVPSEQERTLIFKYLIDFDQKTTPKVTEGTRELSFAPRNDLSLSSLSLQSAGLTPRDLISIVENAKTLAVDRVESLAKHHNVSFENMVYSSGGYIKFTPEDVEKSINTARNKFSDSIGAPRIPNVKWEDVGGLDVVKDEILDTIDMPMKHPELFSNGIKKRSGILFYGPPGTGKTLLAKAIATNFALNFFSVKGPELLNMYIGESEANVRKVFQRARDAKPCVVFFDELDSVAPKRGNQGDSEGVMDRIVSQLLAELDGMSGGDGGDGVFVVGATNRPDLLDEALLRPGRFDKMLYLGVSDTHEKQSKIMEALSRKFHLHPSVDLDKVAESCPFTFTGADFYALCSDAMLNAMTRIANTVDEKIKRYNEELPEKSQVSTRWWFDNVATKEDIDVLVTLEDFDKSRKELVPSVSAEELDHYLRVRQNFEGGKEKKVVQENGQTEHFSNGSANNHITFGDEQVVEAIDENGNSIIA
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling.  Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel.  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
What are the official names of this protein?
Peroxisomal ATPase PEX6, Peroxin-6, Peroxisomal biogenesis factor 6, Peroxisome biosynthesis protein PAS5.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=It may be associated with the cytoskeleton or it may be cytoplasmic.
Protein: PSA2_DICDI
Sequence: MDSDYSFSLTTFSPSGKLVQIEHALQAAASGGSAIGIKAKNGVVLITEKKLHSLVDVTSVQKISMITENIGLVYAGMGPDSRVLIKKARKESEKYYKQYKEKIPVLQLVRELASIMQEFTQSGGVRPFGVSLLVAGFDEKGPHLYQVDPSGSYFAWKATAIGKNMVSSKTFLEKRYSDDLEIEDAIQTALITIKEGFETQLTEFNMELAIIGKNQEFKILTPAQIKDYLLNL
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Proteasome subunit alpha type-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYE_LACJO
Sequence: MAKQKIRVRYAPSPTGHLHIGNARTALFNYLFARHNKGTMVLRIEDTDQKRNVEGGSKSQMENLHWLGIDWDEGPDKGGDFGPYRQSERKDIYNKYIQQLIDEGKAYYSYKTEEELEAQREEQRAMGIAPHYTYEYEGMTADEIKEAQAAAEAKGLKPVVRIHIPENRTYAWEDMVKGKVSFESDTIGGDFVIQKRDGMPTYNFAVVIDDHLMEITHVLRGDDHVANTPKQLVVYEALGWEPPKFGHMTLIINSETGKKLSKRDESVLQFIEQYRDLGYLPDAMFNFITLLGWSPVGESEIFSQRELIKSFDPKRLSKSPAAFDQKKLEWINNQYVKKADRDLLLDLALNNLQEAGLVDKEISPEKMEWVRQLVNIYAVQMSYTKQIVDIAKIFFEEAPELSDAEIEEIKKDDARPVIEEFKKQLNAVPRFTAVQAMNAIQATRRETGVKGRKLFMPIRIAATRSMVGPGIGEAIELMGKEKVNKHIDLTLKQLSDLGL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BICC_DROME
Sequence: MLSCASFNKLMYPSAADVAKPPMVGLEVEAGSIGSLSSLHALPSTTSVGSGAPSETQSEISSVDSDWSDIRAIAMKLGVQNPDDLHTERFKVDRQKLEQLIKAESSIEGMNGAEYFFHDIMNTTDTYVSWPCRLKIGAKSKKDPHVRIVGKVDQVQRAKERILSSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNIKRIMDDTHTHIHFPDSNRSNPTEKSNQVSLCGSLEGVERARALVRLSTPLLISFEMPVMGPNKPQPDHETPYIKMIETKFNVQVIFSTRPKLHTSLVLVKGSEKESAQVRDATQLLINFACESIASQILVNVQMEISPQHHEIVKGKNNVNLLSIMERTQTKIIFPDLSDMNVKPLKKSQVTISGRIDDVYLARQQLLGNLPVALIFDFPDNHNDASEIMSLNTKYGVYITLRQKQRQSTLAIVVKGVEKFIDKIYEARQEILRLATPFVKPEIPDYYFMPKDKDLNLAYRTQLTALLAGYVDSPKTPSLLPPSLAGQLTPYANNNHLLLNANGLATPTGVCAPTQKYMQLHNSFQQAQNRSMVAGGQSNNGNYLQVPGAVAPPLKPPTVSPRNSCSQNTSGYQSFSSSTTSLEQSYPPYAQLPGTVSSTSSSTAGSQNRAHYSPDSTYGSEGGGVGGGGGGGARLGRRLSDGVLLGLSNSNGGGGNSGGAHLLPGSAESYRSLHYDLGGNKHSGHRAFDFDMKRALGYKAMERTPVAGELRTPTTAWMGMGLSSTSPAPAPLENGENGAAGGGASSGWRLPPGLGSPYGLSATTGLLDATPVNRRMQLAKHKDIQTLLTSLGLEHYIKIFVLNEIDLEVFTTLTEENLMELGIAAFGARKKLLTAIHTLLANEAACSTMPSSSSSQNSSSPRFSGSAAPGAERRPSNQW
What is the function of this protein?
RNA-binding protein that is involved in oogenesis.  Required for correct targeting of the migrating anterior follicle cells and the establishment of anterior-posterior polarity in the oocyte.  May act as translational repressor of oskar during oogenesis.  Function seems to be sensitive to small changes in expression.
What are the official names of this protein?
Protein bicaudal C.
What is the protein family that this protein belongs to?
Belongs to the BicC family.
Protein: RL1_BRUC2
Sequence: MAKISKRINKIREGVDRNKLYDLSAAIGLVKERAVAKFDETVEIAMNLGVDPRHADQMVRGVVNLPNGTGRTVRVAVFARGDKAEEAKKAGADIVGAEELFEIVNGGKIEFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTTDVAAAVAASKGGAVEFRVEKAGIIHAGIGKVSFDNAKLEENIKAFADAVIKAKPSAAKGEYVKRVSISSTMGVGVKVDPSTVKVVD
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YCF54_NEOYE
Sequence: MTTYYFALASQNFLLVQEPLEEVFRERVNYYQSNNKAIDFWLIPNPSFLEKPEMISFKNLVPKDAVAIISTNPIFINWLKLRIGYICIGQFEDNLQLSEESLNITVLTDKI
What are the official names of this protein?
Uncharacterized protein ycf54.
What is the protein family that this protein belongs to?
Belongs to the ycf54 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSBN_NOSP7
Sequence: MEPAIVLSISMAAVVVAITGISIYTSFGPPSKELNDPFDDHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: COA3_LODEL
Sequence: MTPALYRVRQPFFWRNTISLFVIGSIPLAAYWYTFTKMTEDEFSDIPIPPISDEELTKLKKEYEAGKQ
What is the function of this protein?
Required for assembly of cytochrome c oxidase (complex IV).
What are the official names of this protein?
Cytochrome c oxidase assembly factor 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COA3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: VP4_ROTRH
Sequence: MASLIYRQLLTNSYTVDLSDEIQEIGSTKTQNVTINLGPFAQTGYAPVNWGPGETNDSTTVEPVLDGPYQPTSFNPPVDYWMLLAPTAAGVVVEGTNNTDRWLATILVEPNVTSETRSYTLFGTQEQITIANASQTQWKFIDVVKTTQNGSYSQYGPLQSTPKLYAVMKHNGKIYTYNGETPNVTTKYYSTTNYDSVNMTAFCDFYIIPREEESTCTEYINNGLPPIQNTRNIVPLALSARNIISHRAQANEDIVVSKTSLWKEMQYNRDITIRFKFASSIVKSGGLGYKWSEISFKPANYQYTYTRDGEDVTAHTTCSVNGMNDFNFNGGSLPTDFIISRYEVIKENSYVYVDYWDDSQAFRNMVYVRSLAANLNSVICTGGDYSFALPVGQWPVMTGGAVSLHSAGVTLSTQFTDFVSFNSLRFRFRLTVEEPSFSITRTRVGGLYGLPAAYPNNGKEYYEVAGRLSLISLVPSNDDYQTPITNSVTVRQDLERQLGELREEFNALSQEIAMSQLIYLALLPLDMFSMFSGIKSTIDAAKSMATSVMKKFKKSGLANSVSTLTDSLSDAASSISRGASIRSVGSSASAWTDVSTQITDVSSSVSSISTQTSTISRRLRLKEMATQTEGMNFDDISAAVLKTKIDRSTQISPNTLPDIVTEASEKFIPNRAYRVINNDEVFEAGTDGRYFAYRVETFDEIPFDVQKFADLVTDSPVISAIIDFKTLKNLNDNYGISRQQAFNLLRSDPRVLREFINQDNPIIRNRIEQLIMQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact (PubMed:20375171).  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry (PubMed:29136651).
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers (By similarity). Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non- structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway (PubMed:10708448, PubMed:16571810, PubMed:29263265). SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.