PharMolix/UniProtQA huggingface dataset:
Protein: UBIE_BRUA2
Sequence: MSQQNGNVNRVGAQDRVGASGGMEHSFGFKAVDENEKQGLVNDVFHKVAKRYDIMNDLMSAGMHRVWKDAMVAWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGRQAHVTILDINGSMLGVGRERAIKKGLIDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVPHIDKALSEAYRVLKPGGRFLCLEFSEVELPVLDKVYDEWSFRAIPRIGKMITGDADSYSYLVESIRKFPKQQDFAAMIEKAGFERVSYRNFTGGIAALHSGWKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: NADE_PSEPK
Sequence: MQAVQQEIAQALKVQPPFADAAALEAEVARRVAFIKDCLANARLKTLVLGISGGVDSLTAALLAQRAINELRAETGDKAYTFIAVRLPYQVQHDEHDAQACLEVIKADEVHTVDIAPAVRALAAEVAALKNGSPTLVDFVVGNVKARTRMVAQYTIAGARAGLVIGTDHAAEAVMGFFTKFGDGACDLAPLSGLVKNQVRAIARSFGAPESLVEKVPTADLEDLEPGKPDEASHGVTYAQIDAFLHGQPVDQAAFDIIVATYRKTQHKRELPFAP
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: TATD_ENT38
Sequence: MFDIGLNLTSPQFANDRDDVVARAFAAGVKGLLLTGTNLHESEHAQQLAQGYERCWSTAGVHPHDSSQWTDESAETLYKLAKTEEVVAIGECGLDFNRNFSTPVEQEAAFTAQLAIAAELEMPVFMHCRDAHERFLTLLEPWRDKLPGAVLHCFTGSRQEAVECLNRGLYLGITGWVCDERRGLELRELLPVIPADRLLVETDAPYLLPRDMKPKPASRRNEPAYLGHIVERIAHWRGEERQRLDAQTDENVRRLFGITF
What is the function of this protein?
3'-5' exonuclease that prefers single-stranded DNA and RNA.  May play a role in the H(2)O(2)-induced DNA damage repair.
What are the official names of this protein?
3'-5' ssDNA/RNA exonuclease TatD, DNase TatD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPNE_DROER
Sequence: MDQEVMDFFDFSKEFKREAAPQGYISSDPSIMATETNESKVPKREVIGTDYVPEIVAKEKCLLDRTLRDDCPQSKRNRTLDDLDTDDEGEETEIRRDDEYYKRYRFNLNRDKNLPIYAKREEILAAINAHPVVILKGQTGCGKTTQVPQYILDEGYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQDTVCSYQVGLHRPTSLEDTRLLYCTTGVLLNNLINKKTLTHYTHIVLDEVHERDQDMDFLLIVVRRLLATNSRHVKIILMSATIDARELADYFTTTNSVPPVITASHGRKHAIEKFYRDQMGSIRWKEEEDDQLVPQINDHGYRAAVKIIMVIDNMEREAAIQSRLSYDEALRYGAVLIFLPGIDEIDTMAENITSMLQSDRNIKVFIVRCFSLMTPENQRDVFHPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLTKVLVTDTATSFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKSFYQREMAEFGIPEMLRMPLQNSVLRAKELEMGSPIEILALALSPPNLSDIQNTILLLKEVGALFLTVDGVYNAMDGDITYWGTIMSRLPLDTRLSRLIILGYVFNLLEEAIIIAAGLSMRGLYVNEGRRTQGADSFWMHYIFADGSGSDLVAIWRVYLTYLNMVEIAHEQESAIRWAKRFHVSLRSLKEMHLLVQELRWRCTNLGLIPFAVNPSQMMGDREKSIILKVIIAGAFYPNYFTRSKESCAEPDRNIYQTISGHDPCRTVYFTNFKPAYMGELYTRRIKELFQEARIPPENIDVTFQQGSQKVFVTFKQDDWLADSSKFVSVSGRVQSEVYKAVRMRLDRIQRPIRIMTQNNFMNYVQQRGIGDVIEGRWIPPTKPLNVELLALPSVFSKTITGLITCIISCGKFFFQPQSFAECIRNMSEIFNAPQQLRNYVINAGAITKGMMVLAKRDSNFQRATVIRPENQSNRQPMFYVRFIDYGDCALLSMQQLRLMPKELIQQYGDLPPRVFECRLAHVQPSSVVSGNNRWPTAANDLLKSVAKCGRIDIEVYSLFNNVAAVLIPMKDGIINDMLVELKLSRRSDEDYMSRKDHDFRLRRQESARYLTLTERQQINEEYLRSCQLPQDLDLPPPPLDKCNTIVMLKGPSSPLECSMQSIIRVGSSKRVNIDNASVNAVLLDADPQDHHDHLIVAHATVESTNGQTLTARGTTLMPNVQGFGALMVMLFCPTMQLKCNNEGTSYVSILAGLGCDPVTGEPYYAEHDVLINLDVNILEDDVVLINQIRYYIDSVFFNFKEEKDPAVSINERVSIYTQLRSLINRLLCKDRSYMQRNMSNSDFEWESNPELPMPNEPFGKRAIFPMHSLTELQEEDMGRLMHLRENCSMLHKWRNFEGTLPHMTCKLCNQLLESVPQLRLHLLTVLHRDREKQIDYCNQ
What is the function of this protein?
Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons.  Involved in the repression of LTR retrotransposon copia.  Also involved in telomere regulation by repressing specialized telomeric retroelements HeT-A, TAHRE, and TART; Drosophila telomeres being maintained by transposition of specialized telomeric retroelements.  Involved in telomeric trans-silencing, a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin.  Involved in the repression of testis-expressed Stellate genes by the homologous Su(Ste) repeats.  Required for anteroposterior and dorsoventral axis formation during oogenesis (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase spindle-E, Homeless.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Protein: RRAAH_ALBFT
Sequence: MTPSFATCDLCDAHKNDVSGAFRVLPPVFRDFGGVRQFCGPVVTVKCFEDNSSVKAAVESVGYQETPAGRVGKVLVVDGGGSLRRALLGGNLGAAAARNGWAGVVIDGCVRDVSELAAVGLGIRALASMPLPTEKRGEGQSDLALQIQGVWVRPGDWLYADEDGMVLAAGRLV
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: RRAAH_PSEMY
Sequence: MHYITPDLCDAYPELVQVVEPMFANYGGRDSFGGQMVTIKCHEDNSLVKEQVDLPGEGRVLVVDGGGSLRRALLGDMLAEKAAKNGWAGIVVYGCIRDVDVIAQADLGVQALASHPMKTDKRGIGDLNVPVTFGGVTFKPGEYLYADNNGIIVSPQALSMPE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: GLMM_ANADE
Sequence: MARRLFGTDGVRGVANVHPMTAEMALQLGRALAYIVRSGPHRHRIVIGKDTRLSGYMLEQAIASGICSMGVDVMLCGPLPTPGIAFVTHSMRADAGVVISASHNPYQDNGIKFFSRDGFKLPDELELQIERLVLDAGEDDAGAEEFRALRPTATRIGKAKRIDDAIGRYAQFLKTIFPKELTLDGLTVVVDCAHGAAYHVAPAVFEELGAKVIPLNVKPDGKNINDACGAVHPESMARAVKRHGANLGLALDGDADRVILADEHGNVVDGDAIMALVGRDLLARKALAKRTVVATVMSNLGLERALAPLGGKVVRTAVGDRYVVEEMRRSGYSFGGEQSGHLVFLDHVTTGDGVAAGLNVLAVMVREGKPLSELARCFEPFPQALVNVEVREKRPVAELPGVAKAIAAAEKALGAEGRVLVRPSGTENKVRVLVEGPDAKRARALADGIAAELRQAIG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: HIS6_BAUCH
Sequence: MLAKRIIPCLDIHNGQVIKGMQFRNHKVIGDIVPMAQRYAKEGADELVFYDITASSEGRVVDKSWIARVAEVIDIPFCVAGGIKSVAQAGEVISFGADKISINSPALNDPYLISRLADRFGVQCIVASIDTWYDIQLDRYQVNQYTGDENRTKVTNWQTLDWVQEVQKLGAGEIVLNMMNQDGVCRGYDLQQLRLVRQTCHVPLIASGGAGTMQHFQEALINAEVDGVLAASVFHKNIINILELKKFLAREGVEIRLC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_CAMHC
Sequence: MIFIDACLKKKTPYTPVWMMRQAGRYLPEYMKVRNEVGGFLELCKNYKKASEVTIQPVEILGVDAAILFSDILVIPLEMGMDLHFIKGEGPIFESPVKNENDLAKLSLQKAVKNLQYVYDTISLTREKLPKDKALIGFCGAPWTIATYMIEGKGSKTYSVCKKLLYTNPEFLHKILTLITETLKLYLENQIKSGVNTVQIFDSWASALECEAFFEFSWKYIIEICDFIKAKYPQIPIIVFPKGISGYLDKIYGNFDVFGVDWSTPLESASKILSAKYTLQGNMEPCRLYNKNAIKESVEQILNTMKGKPHIFNLGHGILPDIPVENAKYFIRLVQERSSL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_DESPS
Sequence: MDVFQTIILGIIEGITEFLPISSTGHLIVASNWLSIEQNETNKAIEVIIQLAAILAVIANYRDKFTLKHKVLWSKVVLAFIPIGAIGLLFHKEIKTLFTVPMVGTMFIVGGIVFLVLEHFYQERSSHVQEVEAISYRQALWIGIAQVFALIPGTSRAGASIVGALLMGLSRKASAEFSFLLALPVLAAAAGFDLLTHYSDFSRGDMLTLSVGFITSFLIAYLTIRVFIGFLQRFTFVSFGIYRIAFGALLLWLG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OL688_MOUSE
Sequence: MGTALHETNSSEVHVSEFILLGFPGIHEFQIWLSLPMALLYIVALGANLLILITIYLEPTLHQPMYQFLGILAAVDIGLATTSMPKILAILWFDAKTISLPECFAQIYAIHTFMCMESGVFLCMAIDRYVAICYPLQYPSIVTEAFVIKATLSMLLRNGLLTIPVPVLAAQRQYCSRNEIDHCLCSNLGVISLACDDITVNRFYQLALAWLVVGSDMILVYASYALIIRSVLRLNSTEAASKALSTCSSHLILIMFYYTAIVIVSVTHLAGRRVPLIPVLLNVMHIVIPPSLNPVVYALRTQELKVGFRKVFSLSEFVSRK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 688.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVA_BACCR
Sequence: MFEYVTGYVEYVGPEYVVIDHNGIGYQIFTPNPYVFQRSKQEIRVYTYHYVREDIMALYGFKTREERLLFTKLLGVSGIGPKGALAILASGQTGQVVQAIEHEDEKFLVKFPGVGKKTARQMILDLKGKLADVVPDAFVDLFSDTERFDEKKGSSAELDEALEALRALGYAEREVSRVVPELLKESLTTDQYIKKALSLLLNGKR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: THII_LIMRJ
Sequence: MQYTEIMVRYGELSTKGHNKKSFIDRLGVNVRKALHSFDQVKVHAQRDRLHVELNGADYDQVMNRLKLVFGIQNFSPSIKVDKTFEATAEAAAQMIAEQVDKPITFKVETRRSDHQFAIDTFEMNNKLGGYLLDKFPDKLKVDVHHPDLTLRVEIRLNGIFLSSETIKGAGGLPVGTAGKGMMMMSGGIDSPVAAYLGMKRGVSMEMVHFFSPPYTSPQALAKAKQLTERLAKYSGSIKFIQVPFAEIQETVKEKVPEGYLMTIQRRMMLRLAAALMIKRHGLAIFNGESLGQVASQTMESMLAINDVTSYPVLRPVLSFDKTEIIKIAQDIDTYDLSILPYEDCCTVFTPPSPKTRPNVKRAREYEKRLDIEGLMQRALDGIEITEIHPGEDYLNQNEDVFAELL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHZB_PSEFL
Sequence: MPDSTVQQPITDDTELRRKNRATVEQYMRTKGQDRLRRHELFTEDGSGGLWTTDTGAPIVISGKAKLAEHAVWSLKCFPDWEWYNVKVFETDDPNHIWVECDGHGKILFPGYPEGYYENHFLHSFELQDGKVKRNREFMNVFQQLRALGIPVPHIKREGIPA
What is the function of this protein?
Involved in the biosynthesis of the antibiotic, phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control.
What are the official names of this protein?
Phenazine biosynthesis protein PhzB.
What is the protein family that this protein belongs to?
Belongs to the PhzA/PhzB family.
Protein: PANC_EXISA
Sequence: MRIVSTVEELRSALPMDQTIGFVPTMGYLHEGHMSLVENARRENDVVVMSIFVNPTQFGPNEDLDRYPRDFERDEKLAREAGVDVLFYPTTETMYPLDMARVTVRHGADVLCGASRPGHFDGVLTIVSKLFNLVQPTRAYFGLKDAQQVALIEGYVRDYFVPVEIRRCPIIREETGLAKSSRNVYLSDIETVEASRIFSALTMAREALDAGQQVDEVKRQLIERLDEIPNSQIDYVELVDYPTLGAVSSDSTELLLAVAIQFERARLIDNVIWKKG
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SANA_ECOL6
Sequence: MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPYRQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTMRKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHMGIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPEDAQGYPAVTPEQLLELQKKQGK
What is the function of this protein?
Participates in the barrier function of the cell envelope.
What are the official names of this protein?
Protein SanA.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AROB_KLEP3
Sequence: MERLTVTLGERSYPITIAAGLFNDPASFLPLKSGDQAMLVTNETLAPLYLDTVRSVLEQAGVNVDSVILPDGEQYKSLAVMDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFWQPVSVVVDLNCLKTLPARELASGLAEVIKYGVILDGEFFSWLENNIDALLALDEKAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAAHTSERLGQFRAQDTQRIIDLLKRAGLPVRGPQEMSAQAYLPHMMRDKKVLAGDMRLVLPLAIGSSELRGGVPHDVVLGAIADTQQAQQ
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_CLAL4
Sequence: MEEKSQVQLDSHIFNTTSSSSQYYPLNVMISRSIKGWRPEPGYPFKCGIEIHTQLKTKHKLFSLSKNSPGAAPNTCASYFDFGLPGTIPKLNPEALLLALRAAVALKSDISSISSFDRKHYFYMDQPLGYQITQHYQPLAKNGHLSLVPRLDDVEEAKTIHVEQIQLEQDTAKLNYNAYDGTVDIDHNRANVPLIEMVTKPDFSHLSELRAFVKKYISLMTHLGVCSGDMENGALRCDVNVSVAGGNRVEIKNLGSTSEIIAAAKYEYARQVQLLKHGKTPVEQETRSWDGTKTIRTRSKEDAIDYRYFPDVELPRIRLHPSIGKDLSQTLPELPEQLIQQLCEEPFLLEVKHARFLVENPDLYNYYKNLHHIIVDKHKLSYKVVNNWIIHEFIGAFNKLDIPVDVSVIDTEKLASLIIMVSEKKISITSAKLLLTQILQSPEDRELSIPDLIDAYDLGAVNDIHGDDLKEAIKEVCSEVIDSHPDVVTKIRNGKTKSINFLIGRAMKETQGKVDSKEFEKMFKKLIG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BGBP_BOMMO
Sequence: MYKTCVWVLLFKIVLCYEAPPATLEAIHPKGLRVSVPDEGFSLFAFHGKLNEEMEGLEAGHWSRDITKPKNGRWIFRDRNAALKIGDKIYFWTFVIKDGLGYRQDNGEWTVEGFVDEAGNPVNTEGSEITPGVEFTSTSLNPESPQSIPNQPPDNLPAKPPSEGYPCELSLSTVSVPGFVCKGQLLFEDQFNIPIHRGKIWVPEVKFPGEPDFPFNVYLSDNAEVNDGKLIIKPATLESKYGEDFVRQSLDLSERCTGTVGTAQCLREASGPLILPPIITAKISTRHQFAFKYGRVEIRAKMPKGDWLYPEILLEPRDNIYGVRNYASGILKIASVKGNAEFSKKLYAGPIMTGSDPYRSFYLKENIGYESWNNDFHNYTLEWRPDGITLLVDGESYGEIKPGEGFYNVANSYKVEAAPQWLKGTIMAPFDELFYVSIGLNVAGIREFSEDISNKPWKNSATKAMLKFWDARSQWFPTWDEDSALQVDYVKVFAI
What is the function of this protein?
Involved in the recognition of invading microorganisms activating the phenoloxidase cascade (PubMed:10671539, PubMed:3136171, PubMed:19561300).  Binds specifically to beta-1,3-glucan (PubMed:10671539, PubMed:3136171, PubMed:19561300, PubMed:21697086).  Binds to both curdlan, a linear water-insoluble beta-1,3-glucan polysaccharide, and laminarin, a water-soluble beta-1,3-glucan polysaccharide containing beta-1,6 branches (PubMed:19561300).
What are the official names of this protein?
Beta-1,3-glucan-binding protein, BGBP, Beta-1,3-glucan recognition protein, BetaGRP, Gram-negative bacteria-binding protein 3, GNBP3.
What is the protein family that this protein belongs to?
Belongs to the insect beta-1,3-glucan binding protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RESA_GEOTN
Sequence: MKKQQRLVMRTVILLLLLAALGYTIYANFFTEKTAVAVGSTAPDFVLSDLEGREHRLTDYRGKGVFLNFWGTWCKPCEREMPYMNELYPIYQKQGVEILAVNVGEPKLNVEKFAERFGLTFPIVIDRQDQVLNAYGVGPLPTTFLIDKNGKVKKIITGTMTKEDIKQHLESIKP
What is the function of this protein?
Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis.  May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached.
What are the official names of this protein?
Thiol-disulfide oxidoreductase ResA.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. ResA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane.
Protein: HIS52_LEGPH
Sequence: MIAVIDVSGNNLTSLTNALIRLGGHFALTHDAEEIQKASHVILPGVGTARSGMTALQQNGLIDVLRTLTQPLLGICLGMQLLLEYSEEDDIPCLGLIPGVAELLKAERNHPVPHMGWNNLHWQKTSSLQQGLNNSDYVYFVHSYALKADNYALARCQYHEEFTAVVKKGNFYGMQFHPEKSANVGMVLLNNFLSLESTC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH 2, IGP synthase glutaminase subunit 2, IGP synthase subunit HisH 2, ImGP synthase subunit HisH 2, IGPS subunit HisH 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IAPP_CAVPO
Sequence: MCLLRLPVTLLVLCVALNELKATSIASDTGHQVGKRKCNTATCATQRLTNFLVRSSHNLGAALLPTDVGSNTYGKRNAPQISDRELLHYLPL
What is the function of this protein?
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
What are the official names of this protein?
Islet amyloid polypeptide, Amylin.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZFP57_RAT
Sequence: MAAKKQSKSAKALRTTVRYEDVAVSFTQEEWEYLTSTQKTLYQKVMSETFKNLTFVESKKKPQEPNPNLKDKDDDKSSTCTGVFKGGPFFFCLTCGKCFKKNTFLFNHQFPVRSRRLAVTKPQSRKALGHKPQHRGDRPFFCNLCGKTYRDASGLSRHRRAHVGYRPRSCPECGKCFRDQSEVNRHLKVHQNKKPVAGSHVKVHQNKPVASNQKQKGRVPPTTRESPAPALRHLKVIQGPVARAKARSSRASSLEVRSTSVTVARPREKVYCPYCRITFTMRTCLLNHLKIHFRRQPNQHFCCKESHSSNTLRMQKIYNCPVCDSSFRGKESLLNHLCSRRPIRLSKCWEILGHLLGYLREPLGNIFKVRESRKRRRKRISSDSSETEGPSGSDEVMEVDTDSDLS
What is the function of this protein?
Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation.  Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs).  Acts together with ZNF445.  Required for the establishment of maternal methylation imprints at SNRPN locus.  Acts as a transcriptional repressor in Schwann cells.  Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element.
What are the official names of this protein?
Zinc finger protein 57, Zfp-57.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Note=Binds various differentially methylated regions (DMR), including the Snrpn DMR.
Protein: VA52_VESCR
Sequence: NNYCKIKCRSGIHTLCKYGTSTKPNCGKNVVKASGLTKQENLEILKQHNEFRQKVARGLETRGNPGPQPPAKSMNTLVWNDELAQIAQVWANQCNYGHDNCRNSAKYSVGQNIAEGSTSADNFVNVSNMVKMWEDEVKDYQYGSPKNKLNKVGHYTQMVWAKTKEIGCGSEDYIEDGWHRHYLVCNYGPAGNVGNEPIYERK
What are the official names of this protein?
Venom allergen 5.02, Allergen Vesp c V.02, Antigen 5-2, Ag5-2, Cysteine-rich venom protein, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family. Venom allergen 5-like subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SEPF_PROMS
Sequence: MSLISRLKAVVAGDEYLDDDFDELDYPSEDELNDINNFKQNPKNSNALANSNPFDFMNNNRSSKVVGMPGISNSSSEVSLMEPRSFDEMPQAIQALRERKTVILNLTMMDPDQAQRAVDFIAGGTYAIDGHQERVGESIFLFAPSCVNVTSSSPEEASPSSVSTENTPQYSLGKNTTPEPAWGNSKLSAYS
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.