PharMolix/UniProtQA huggingface dataset:
Protein: BPT_BRUA4
Sequence: MTHQPQQSPQFFLTAPSPCPYLEGQMERKVFTHLVGDKANEINDLLTQGGFRRSQNIAYRPACELCRACISVRILAGEFKMTRNMRRVWTQNNDLIGRVHKAQPSTEQYALFRDYLDARHRSGGMSDMTVLDYAMMIEDTHVNTQIIEYRKRGPESFISAKGDGELIAVALTDVMADGLSMVYSFFSPHMHDRSLGTYMILDHIQRAHAAGLPHVYLGYWVEGSRKMQYKIRFTPQEHLGPRGWQRFEG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_HELMI
Sequence: MKIDVLTIFPEMFTGPMDVSIIGRAREKGILSFNAHDVRAYTTNKHRRVDDTPFGGGAGMVMNAQPFFDALAAILGPRELRDPLRSRVVLLTPQGAVFSQAKARELSGLQQLVLICGRYEGIDDRVRQAWVDEEISIGDYVLTGGELPAMVVIDAVVRLLPGALGDETSAEEESFSDGLLEYPQYTKPALFRGMEAPPELLSGHHAAIRRWRRKEAFKRTYQNRPELLIGRPLPFDDQVLLAEALRELGLDAEIPEKPKKKRAKGREPRT
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_STRAW
Sequence: MRTYSPKPGDITRQWYVIDAQDVVLGRLATTAANILRGKHKPIYAPHVDAGDFVIIINADKVHLSGNKKTQKLAYRHSGYPGGLRSVRYDELLAKNPEKAVEKAIKGMIPKNTLGRQVLSKLKVYSGDQHPHAAQQPVPFEITQVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS18_KLEP7
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: LPXK_ALCBS
Sequence: MGSLSEWVQQGWYKGSPWLVPLRPLSALVSFEARRRLQRFRKQRPRPPVPVLVVGNITVGGTGKTPLVIALVEAARSRGLKVAVVSRGFAGKTNHYPQHVTASSDALDMGDEPVLIARRTGVPVVLDPDRRNALDVAIREYAPDLVISDDGLQHYALPRSAEVVVVDAQRGLGNGRCLPEGPLREPATRLKEVDFVISTGGGWAGAYPMIMRPSGVTCLADNRTLTPDDFLRLHPQVHAVAGIGNPKRFFNLLSILGLSATPHVFPDHHAYQPADLAFTDGLPVLMTEKDAVKCAPFAEPHWWFVPVTASLPEGLLDQMLDRALGKE
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RSRP1_DANRE
Sequence: MKTEASPGRLHEDVKLIFDKKAPSGRSSSCSSSSSSSSGSSYSSSRGSRSSRRSRTSSSSRSSSSGSSSSSNSRSRSRPRCSGRVHCRHRHRSPPRRYRARSRSYSPSPESSSRRRHYYRRSRSPYRYSRRYRRSPSRSRSRSPPHWRGSRFIGRYRCRFSQSPRRSPRPYRSRSRSRERSIRLSLEEKKYLLNVAKANAARILGVQNLELPESLKEMEQQEERKRRSSSDEEERVRVDLAAQKTPAQVNGGAADDEAETAQTSPKRKQIVFSNNNAIAKPSSSPTLSDSKVTSRADIVPYKRPFGQWVPIGKSSSANKR
What is the function of this protein?
Probably acts as a spliceosomal factor that contributes to spliceosome assembly and regulates the isoform switching of proteins such as PARP6.
What are the official names of this protein?
Arginine/serine-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the RSRP family.
Protein: LPTC_ECOLI
Sequence: MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKSEHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAKLTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSGLKMRGNLRSKNAELIEKVRTSYEIQNKQTQP
What is the function of this protein?
Involved in the assembly of lipopolysaccharide (LPS).  Required for the translocation of LPS from the inner membrane to the outer membrane.  Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA.  Could be a docking site for LptA.
What are the official names of this protein?
Lipopolysaccharide export system protein LptC.
What is the protein family that this protein belongs to?
Belongs to the LptC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: EXO74_BPE32
Sequence: MVKKKKKVFAFDIESNALYDDITKVWCIYIFDVETGERWGYRPHQIEDGIRKLTEADVLVGHNIIDFDLPALKKMYPSLINYHFNVFDTLCLSRYLKPDRIGDSPEYPKGDPRRGPRGHGLKQWGEFLGELKGDYGEQEEAWDAFTEDMFTYCEQDVNLTVKVYLFLCELTGFDPYDPPSLYWKM
What is the function of this protein?
Probable 3'-5' exonuclease involved in viral DNA replication.
What are the official names of this protein?
3'-5' exonuclease gp74.
Protein: RBL2_HETTR
Sequence: MPSSSFTTGLALGAGALVGANAFVAPTAKTTNLRAPTQEASLQVAASQQTEQPAPSTSALPWAFGAGACLALAAGGQRKQRSAIAQGRATVLPTASPVVRRALDQSSRYADLSLSEEQLIANGKHVLVSYIMKPKAGYDYLATAAHFAAESSTGTNVNVCTTDDFTKSVDALVYYIDPENEECKIAYPNLLFDRNIIDGRAMMCSVLTLTIGNNQGMGDVEYGKIYDIYFPPSYLRLFDGPSCNIIDMWRILGRGTTDGGLVVGTIIKPKLGLQPKPFGEACYAFWQGGDFIKNDEPQGNQPFCQMNEVIPEVVKAMRAAIKETGVAKLFSANITADDPAEMIARGKYVLAQFGPLSENCAFLVDGYVAGGTAVTVARRNFPKQFLHYHRAGHGSVTSPQTQRGYTAFVHTKLSRVQGASGIHVGTMSFGKMEGDASDKNIAFMLQDDAADGPYYHQTWEGMAETTPIISGGMNALRLPAFFENLGHSNVILTAGGGAFGHKDGPKQGATSCRQGEEAWKLWKAGVYGSVSLSDGVIEYAKTHEEIKGAFLTFQKDADQIYPGWKEKLGYTGESSVQAASFDWKKKAAAAAFAGSSTQARTVGVQMRHGYDDVATNTFYYDKRLESFGQQEFFNQVGYLPDGTPMNTAGNLTNHPETIGPDPHINGSELPQAVFVNSIGYLPDGTAMNQAGNAVNHPETMGPDLHMAGSPLPPPLKGYLNDIGYLSDGTPMATAGNLSNH
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase, chloroplastic, RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type II subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane. Note=In this organism the plastid is the result of a secondary endosymbiosis event, and thus is found within the endomembrane system, necessitating a complex targeting process.
Protein: DNAK_CORJK
Sequence: MGRAVGIDLGTTNSVVSVLEGGEAKVIANSEGSRTTPSIVAFAKNGEVLVGQSAKNQAVANVDRTIRSVKRHMGTDWKVSIDDKEYTAPEISARTLQKLKRDAESYLGEDVTDAVITVPAYFNDAQRQATKDAGQIAGLNVLRIVNEPTAAALAYGLEKGDKEQTILVFDLGGGTFDVSLLEIGDGVVEVRATAGDNELGGDDWDQRIVDWLADKFKASHGVDLTKDKMALQRLREAAEKAKIELSSSQQASINLPYITVDEDRNPLFLDETLTRTEFQKITQDLLDRTKTPFQAVLKDAEISVDEIDHVVLVGGSTRMVAVSELVTELTNGKEPNKGVNPDEVVAVGAALQAGVLRGEVKDVLLLDVTPLSLGIETKGGVMTKLIERNTTIPTKRSETFTTAEDSQPSVQIQVFQGEREMAAHNKLLGSFELAGIAPAPRGVPQIEVTFDIDANGIVSVSAKDKATGKENTIKIQDGSGLSQEEIDRMVKDAETHAEEDKKRREEQEVRNSAESMAYQTRKFVEDNKDKVSEDTQNKVEEAAKAVDEALKGDDIEAIKDAVEKLNAESQEMGKAIYEAEAAAGAEGAGADAAGSAANDDPNVVDAEVVDEDTSAEDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NOT1P_XENLA
Sequence: MAGTLCVTLLLLLSTIAVGGRKTWRRRSQQIVPSSWERSEGGGESFPLDFTAVEGNMDNFMNQIKSLAQSLYPCSAQRLDDEMKLHSLHNKSVTCNDGSPAGYYLKESKGSRRWLVFLEGGWYCISRENCDIRYDTMRSLMSSRAWPPSKTASGILSTQPEENPHWWNANIVFIPYCSSDVWSGVSPKTEKSGYAFMGSLIIQEVVKELLGKGLDTAKLLLLAGSSAGGTGVLLNVDMVANLLEELGYPGIEVRGLSDSGWFLNNKQYWRTDCTDIITCAPTEAIQRGIRYWNSMVPERCKQQFKEGEEWNCFFGYKIYPTLRSPVFVVQWLFDEAQLTVDNVHLSRQPVQESQWLYIQNLGRELRNTLKDVGASFAPACLAHEVITRSHWTEIQVRGTSLPRALHCWDRSLQEPNKNSKVQLKGCPFHLMDSCPWPQCNPTCPSIRDHFTGQEMSVVQFLMHLGFDVQKMASQQGMEPGKLLGVLSS
What is the function of this protein?
Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins.  Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.  Functions in the prospective ectoderm and is required for neural induction.
What are the official names of this protein?
Palmitoleoyl-protein carboxylesterase notum1'.
What is the protein family that this protein belongs to?
Belongs to the pectinacetylesterase family. Notum subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RRF_METPP
Sequence: MSIADIKKTFEQKSARSIESFKSELQKIRTGRAHPGILDQVHVEYYGSMVSISQVANVSLLDARTISVQPWEKGMGPKIEKAIRESDLGLNPSSQGELLRVPMPALNEERRRDLTKVVRGAGEDARIAVRNLRRDANDQAKKLLKDKAISEDDERRSLDEVQKLTDRVIAEIDRLVQSKEAEILAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITPA_ASHGO
Sequence: MPNLVFVTGNANKLREVRQLLGGAALPYPLVNEPLDLDEVQAASLDAIALHKCRSAAARLPPGTPVFVEDTALCFDALGGLPGAYIKWYVQAMPLCDIASMLDAFPAKTARAVTTVAYCDAAGAFHTFSGTTTGRIVPPRGPTDFGWDAIFEPAGEDKTYAEMDKDKKNAISHRGKAFAAFREHLCSPSQRPPPPATA
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MRAZ_SYMTH
Sequence: MGEFQHAIDAKGRLIIPAKLREGLGERFIATKGLDRCLFVFPLAEFEAVSQKLRGLGMSSSAARAFNRLFFSGATECELDPQGRILLPANLREYAGIQKDCVIVGVENRVEIWAAERWAEYSEEAGELYTEIAEKLGF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AHI1_MOUSE
Sequence: MEPETPEKVDSAQEKVRGKTPTADDSDDSREKTGIEEKGELTDAYQLQVAEEMAKEIKKKIRKKLKEQLTYFPPDTLLHDDKLASEKRKKKKKKVPVPTKPESSPSDVCDSAVEGEQKKEGTPEDSQHMEGICSREQDVDATVPENAKPKPKKTKKKTKAVSNDNEDTNGDGVHEITSRDSPVHPKCLLDDDLVMGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSERPVSSYYEKDNVDYILPIMTQPYDFKKLKSRLPEWEEQVIFNENFPYLLREFEECPKVILFFEILDFLSMDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSQLNVVEVFEWWSKCPRNRYPSTLYVTVRGLKVPDCIKPSYRSMMALQEERGTPVYCERHRETSSVDTEPGLEDSKEEVKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWDTYVKVNDVQTSVRHWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTKDSTLRIMDLRILAARKFVGAANYREKIHSTLTPCGTLLFSGSEDGIVYVWNPETGEQVAMYSDLPFKSTIRDISYHPLENMVAFCAFGQSEPILLYIYDFQVAQQEAEMLKRYSGTLPLPGIHQSEDALCTCPKLPQQGSFQIDEFVNTENSSSRKIQLVKQRLETVTEVIRSCAAKVNKNLSMTSPPPGPAKKPRVKQSFVLTTDEIIHQFGLPQTAFISIERGPFVRHVDPPPMVVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHVASETLYRDSPPKVKERSPPLTPKEKTKPEKPLASQKQSLSKGRPLDPRLGPQPVGHSEKGKDQNVEDRGHKVDMETKKSEPVVRKVTLIE
What is the function of this protein?
Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium (PubMed:19625297).  Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes (PubMed:22179047).  Involved in neuronal differentiation (PubMed:23658157).  As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development (PubMed:21623382).
What are the official names of this protein?
Jouberin, Abelson helper integration site 1 protein, AHI-1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell junction, adherens junction. Note=In the retinal photoreceptor cell layer, localizes at the connecting cilium.
Protein: UPPP_ANAD2
Sequence: MSLVSAALFGLLQALTEFLPVSSTAHLLVFGELLGHSLDDRRFRAFVTIIQAGTTLAVLVYFRADIARLVAAAARGLARGRPFGTPEARLGWYIVLGTVPAALAGKLLEHRIEALGNWVIAGSLVALGLVLLAAERLASHRRRVEDVGAGDALLIGVAQALALVPGSSRSGTTITGGMLLGFTREAAARFSFLLSVPITLAAGAYKLWSTVPDLRGEAAWTVATVVGTVVSAVAGYLVIDWLLAWLRTRTTYVFVVWRLAAGAAIAALILSGVLPAGAEAPPPPPPALHAAP
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TYR1_SCHPO
Sequence: MKETFQVGIIGFGDMGRLYAEYISKAGWRVNVCDRPENYESIQATYGNGGYTVLKDGFQVSRTSDYILYSVEAEHIDKVVALYGPATKVGAIVGGQTSCKAPEMNAFEKYLPEDVDIISCHSMHGPKVNPKSQPLVIIRHRASDEHFEIVNEILSCFKSSVVYLSAKEHDRITADTQAVTHAAFLTMGLAWHANNQYPWEINRWCGGIENIKMNLSMRIYSSKWHVYAGLAILNPEAQRQIQQYASSVTELFKLAISGKAKEYEDRIRNAGKFVFGENMDRNSSGLLLSDELLDQYSISNIPKDESKRNSHLSILAIVDSWSKLGIHPQNHMICSTPLFRLWVGVSEYVFRHPGLLDSCIYTATKHNDFSPDDLEFVVAVRSWSECVAAKDFTTYKKRFLETQEYFRPRFEEATRVGNAMISKLLENLQKM
What are the official names of this protein?
Probable prephenate dehydrogenase [NADP(+)], PRDH.
What is the protein family that this protein belongs to?
Belongs to the prephenate/arogenate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_PARL1
Sequence: MDLFPLARPLMSLMDPETAHGLTLRALRLGLGPTRRAPDPVSLAIDLFGLHFENPLGIAAGFDKNGEVPDAMLAMGMGFAEVGTVTPLPQPGNPRPRVFRLPVHRAVINRLGFNNQGHAALKKRLLARRKRPGILGVNIGANKDAADRIADYEAGIRAFEGLASYFTVNISSPNTPGLRALQNKAELQNLVARVLAARKGKTPVLLKIAPDLNAEELGDIAEVALEQGLDGLIVSNTTIAREGLVSGVNANETGGLSGAPLFPMSTAVLRDMYRLTGGRLPLVGVGGISSADDAYAKIRAGASLVQLYSALTYDGPPLVARIKQGLAARLAADGFAHLKDAVGADVNL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: QUEC_RUTMC
Sequence: MSNTRHKIKAVILLSGGLDSTTTLAIAKTKNFECYSLSFDYGQKQKSELKSAENFAKIFGSIKHRVMKISLSNIDFSALTDDKIDIPKFSKSDDIPITYVPARNTIFLSYALSWSEVLDCQHIFIGVNTLDYSGYPDCREIYIKAFEVMANLATKQSIEGKKLTIHTPLIHLNKAQIIKKGLSLGIDYSLTTTCYQADKSGKACGICDACEYRKLGFIEAKVADPTRYQI
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: TRMD_SHELP
Sequence: MWLGVVTLFPEMFRAVTDFGVTGRAVSNGLLELQTWNPRDFTHDKHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKVAAGDKAKVIYLSPQGRKLTQQGVEELAKSERLILVCGRYEGIDERIIQTEVDEEWSIGDYVLSGGELPAMTLIDSVSRLVPGVLGKQASAEQDSFSDGLLDCPHYTRPESLDGIDVPAVLLSGNHENIRRWRLQQSLGRTLLRRPELFENLALTDEQTKLLAEFVNTAQAGE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_ECO7I
Sequence: MNEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNRKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRSDRIGWVKGIDDKWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILALLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: FLBT_SINMW
Sequence: MKSTLRISLKSGERIFVNGAVLRVDRKVAIEFLNDVTFLLENHVLQPEDATTPLRQLYFIAQMILINPEGADQSTSMFRKSIVMLVNCFRNDEVLAELKRIDGLVTQGRAFEALKAIRALYPIEDQILNAQEMTPATVEQIRKEIAPWR
What is the function of this protein?
Has a post-transcriptional repressor function in flagellum biogenesis.  Associates with the 5'-UTR of fljK mRNA and promotes its degradation.
What are the official names of this protein?
Probable flagellum biosynthesis repressor protein FlbT.
What is the protein family that this protein belongs to?
Belongs to the FlbT family.
Protein: D42E2_HUMAN
Sequence: MKSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVERL
What are the official names of this protein?
Putative short-chain dehydrogenase/reductase family 42E member 2.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
Protein: RL5_MYCLE
Sequence: MSTAEKVQPRLKQRYRSEIREALNKQFSYGNVMQIPTVVKVVVNMGVGDAARDAKLINGAVSDLALITGQKPEVRKARKSIAQFKLREGMPIGVRVTLRDDRMWEFLDRLTSIALPRIRDFRGLSPKQFDGVGNYTFGLAEQSVFHEIDVDKIDRVRGMDINVVTSATTDDEGRALLRALGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GUF1_PARBP
Sequence: MRGCLQTVRWLTSAWQRPPSYPPLSRAAPCRFFNVSIPRNAQSRKPVSDLERRIAAIPIDRFRNFCIVAHVDHGKSTLSDRLLELTGTIQPGGNKQVLDKLDVERERGITVKAQTCTMLYNYRGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGVQAQTVANFYLAFAEGLKLVPVINKVDLPSADPVRALDQMANTFELDPKTAVLVSAKTGLNVEQLLPTVVEQIPAPVGDHTKPLRMLLVDSWYSTYKGVILLVRIFDGEVRAGDHVGSLATGLKYHVGEVGIMYPGQTAQSVLRAGQVGYIYFNPAMKRSQEAKVGDTYTKVGSEKLIEPLPGFEEPKSMVFVAAYPVDASDFPHLEDSINQLLLNDRSITLQKESSEALGAGFRLGFLGTLHCSVFEDRLRQEHGASIIITPPTVPFKVIWKDGKEEIITNPALFPEEDALRAKVVELQEPFVLATLTFPEEYLGRVIELCESNRGEQKSLEFFTATQVILKYELPLAQLVDDFFGKLKGSTKGYASLDYEESGWRRSSIAKLQLLVNKVPVDAVSRVVHSSQVQKLGRVWVSKFKEHVDRQMFEVVIQAAVGRNIVARETIKPFRKDVLQKLHAADVTRRRKLLEKQKEGRKKLKAVGNVVIEHKAFQAFLAK
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: KR74_ICHVA
Sequence: MSGKVEINEPLIVATSAPLRCNCTGGSHFHGKTIANRALGSSQLMKCYSGLLKRCVRREKYIPVSDRGFLDAYTPQTAPGIVFTGSSLVTDSTLMMAPFNFHRQHVLPLEENFGLERARGDVTVDIRTDTDEAVARGLRSDMYERDAVGHIVSKPQKRTTGEMLDELMMTARLSHGNLVRFLGGVACEETRGGKITVKMVELGLCNLDEFIAEPHWIAPKFAIVRQYTLCKLERDTLSGLEYLHMHGVVHGDFRGAKVIVFPTADDFTFKVNLGESTSLGIAPALSRAPYHRAPETEFTGLIGREADMWAWALTMYRAHTCKDFFKKGDPSEPYRVLGPMDNDALDSRRTGRDGDPVNPEGFGTRLEKNATAVDGGFIGLMGKCLALYPQFRPTARELLVYPRYATLHRISGPGPAPPPVIGAAPAVRVVSNAVEFRSRWGVRPSPAMDPRLEARTSWGKNAVRAVGDFTPSFLYREGGLGDTRPGNKRAITLSRGTLRSYVGTENRLTTEIHRSGGADIVLHKVVGRRPDISRANLEYVMKVSNGFPEWYITIDHYTVGVTNVHLYVGYITDDIVYASAIGLSCPLRVDILKGFEKSTLRVDLMGILVTRGLAYTLRVIRHLKSASIYEAGPHAVGLVFVNPSSRNRFGTVSCDSVKLELGDEPSQLITGSR
What are the official names of this protein?
Protein kinase ORF74.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: NFS1_RAT
Sequence: MLLRVAWRRASLAATSVALRRSSVPTRGLRLRVVDHAPHSAVPSEAEAVLRPLYMDVRATTPLDPRVLDAMLPYLVNYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLVTTQTEHKCVLDSCRSLEAEGFRVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGQICSSRKLYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKLYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACELAQQEMEYDHKRISKLAERLIQKIMKNLPDVVMNGDPKQHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVQKCIHHVKRLREMSPLWEMVQDGIDLKSIKWTQH
What is the function of this protein?
May catalyze the desulfuration of L-cysteine to L-alanine as component of the cysteine desulfurase complex (NFS1:LYRM4), leading to the formation of a cysteine persulfide intermediate.  Acts as a sulfur donor for MOCS3 by transferring the sulfur of the cysteine persulfide intermediate on MOCS3.
What are the official names of this protein?
Cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm. Nucleus.