PharMolix/UniProtQA huggingface dataset:
Protein: TX1A_AUGEZ
Sequence: GVDKEGCRYLLGACTIDDDCCLHLGCNKKYGHCGWDGTF
What is the function of this protein?
Insecticidal toxin that acts, at least partially, by inhibiting insect voltage-gated sodium (NaV) channels of several insect species.  The toxin binds to the voltage sensor in NaV channel domain II and inhibits channel opening by shifting the threshold for channel activation to more positive voltages.  The toxin binding is sensitive to residues in the S1-S2 loop of the domain II voltage sensor.  In vivo, the recombinant toxin causes paralysis and/or death to two dipteran species (Lucilia cuprina and Drosophila melanogaster).  In contrast, the toxin does not show paralytic or lethal effect on the cotton bollworm Helicoverpa armigera and the triatomine bug Rhodinius prolixus.
What are the official names of this protein?
Mu-theraphotoxin-Ae1a, Mu-TRTX-Ae1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 47 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: O16A_CONSE
Sequence: MKLTCVMIVAVLFLIAWTFVTADDSRNGLKNLFPKARHEMKNPEASKLNKRDGCSSGGTFCGIRPGLCCSEFCFLWCITFID
What is the function of this protein?
Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process.
What are the official names of this protein?
Delta-conotoxin-like SmVIA, Delta-SmVIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRHO_STRA5
Sequence: MSEKIRVLLYYKYVSIENAEEYAAKHLEFCKSIGLKGRILIADEGINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLEDNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKDPEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFASEENEAKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPQVANV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: MERR_PSEAI
Sequence: MENNLENLTIGVFAKAAGVNVETIRFYQRKGLLLEPDKPYGSIRRYGEADVTRVRFVKSAQRLGFSLDEIAELLRLEDGTHCEEASSLAEHKLKDVREKMADLARMEAVLSELVCACHARRGNVSCPLIASLQGGASLAGSAMP
What is the function of this protein?
Mediates the mercuric-dependent induction of mercury resistance operon.  In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.
What are the official names of this protein?
Mercuric resistance operon regulatory protein.
Protein: DJB14_XENTR
Sequence: MESNRDEAERCVRIAKAAIEAGDKEKAKRFLSKAERLYPSSEARALLQAFEKNDTAGNGPQSAKMAKGTEQPKAEKDSNASASSDTGKGHTQDQLDGVQRIKKCKTYYEVLGVSTDAGEEDLKKAYRKLALKFHPDKNHAPGATEAFKKIGNAYAVLSNPEKRKQYDLTGSEDQMQNNHRNGGFDYHRGFEADITPEDLFNMFFGGGFPSGSVHTFSNGRARYSHHQHHHHSGHDREDERADGGFSMFIQLMPIIVLILVSLLSQFMVSNPPYSLYPRSGQATKRVTENLQIAYYVSKDFQSEYSGILLQKLEKNIEEDYVANVRNNCWRERQQRSDLMHAAKVYRDERLKVKAESISMENCKELNRLTSLFRGG
What is the function of this protein?
Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway.  Acts by determining hspa8/Hsc70's ATPase and polypeptide-binding activities.  Can also act independently of hspa8/Hsc70: together with dnajb12, acts as a chaperone that promotes maturation of potassium channels by stabilizing nascent channel subunits and assembling them into tetramers.  While stabilization of nascent channel proteins is dependent on hspa8/Hsc70, the process of oligomerization of channel subunits is independent of hspa8/Hsc70.
What are the official names of this protein?
DnaJ homolog subfamily B member 14.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family. DNAJB12/DNAJB14 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: FUCT1_NEMVE
Sequence: MKESLLAKSVRIAAVVAAYWTISISLVFLNKYLLSSPDIKLDAPLFVTWYQCVVTVICLFFLSLLGDRYPWIDTFPAFHIKLSVAKQVLPLSAVFVGMITFNNLCLKNLGVSFYNVGRSLTTVFNVICTYVILGQSTSYKAVICCAVIIGGFLMGVDQEGSSGKISYSGVLFGVLASLCVSLNAIYTKKFIPAVDNNIWRLQLYNNFNACFLFLPLMALLGEIGEVAHFPNLSSAYFWLMMTIGGVFGIAIGYITGLQIKVTSPLTHNISGTAKACVQTIMSVSYFHETKTALWWLSNAMVLGGSMAYTRVRHSEMKKAHTIQASKDDKALQEDGQTKV
What is the function of this protein?
Antiporter specific for GDP-l-fucose and depending on the concomitant reverse transport of GMP.  Involved in GDP-fucose import from the cytoplasm into the Golgi lumen.
What are the official names of this protein?
GDP-fucose transporter 1, Solute carrier family 35 member C1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35C subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RPOA_LOTJA
Sequence: MVREKVRVSTRTLQWKCVESRIDSKRLYYGRFILSPLMKGQADTIGIAMRRILLGEMEGTCITRAKSEKISHEYSTIVGIQEPVHEILMNLKEIVLKSNLYGIRDASICFKGPGYVTAQNIILPPSVVIVDNTQHIANVTEPIQLCIGLQIERDRGYRINTLKNFQDGSYNIDAIFMPVRNANHSIHSYVNGNEKQEILFLEIWTNGSLTPKEALYEASRNLIDLFIPFLHAEEEKLNFENNEHKVTLPLFTCHDLLAKTKLKKKKKEIAFKSIFIDQLELPPKIYNCLKKSNIHTLLELLTKSKEDLMKIEHFRVEDVKHILDILEIEKHFP
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRUD_ECO57
Sequence: MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELVELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RS2_GEOMG
Sequence: MSSVTMKELLEAGVHFGHQTKRWNPKMKPYIFGARNGIYIIDLQKTVRLFKNAYSFVRECAQSGETILFVGTKKQAQDAIGEEASRCNMYYVNQRWLGGMLTNFATVKQSIDRLKRLDAMFADGTVEAYTKKEALQLEKERQKLEKTLGGIKGMGKVPGALFVIDPKNETIAINEAKKLGIPVVAVVDTNCDPDPIDYVIPGNDDAIRAIRLLTSKMADAVLEGAQARDAQLQTGEEEMAAAEGESEQVEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: 017L_FRG3G
Sequence: METMSDYSKEVSEALSALRGELSALSAAISNTVRAGSYSAPVAKDCKAGHCDSKAVLKSLSRSARDLDSAVEAVSSNCEWASSGYGKQIARALRDDAVRVKREVESTRDAVDVVTPSCCVQGLAEEAGKLSEMAAVYRCMATVFETADSHGVREMLAKVDGLKQTMSGFKRLLGKTAEIDGLSDSVIRLGRSIGEVLPATEGKAMRDLVKQCERLNGLVVDGSRKVEEQCSKLRDMASQSYVVADLASQYDVLGGKAQEALSASDALEQAAAVALRAKAAADAVAKSLDSLDVKKLDRLLEQASAVSGLLAKKNDLDAVVTSLAGLEALVAKKDELYKICAAVNSVDKSKLELLNVKPDRLKSLTEQTVVVSQMTTALATFNEDKLDSVLGKYMQMHRFLGMATQLKLMSDSLAEFQPAKMAQMAAAASQLKDFLTDQTVSRLEKVSAAVDATDVTKYASAFSDGGMVSDMTKAYETVKAFAAVVNSLDSKKLKLVAECAKK
What are the official names of this protein?
Uncharacterized protein 017L.
Protein: GUAA_STRA5
Sequence: MTDISILNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITADEIRDINPIGIVLSGGPNSVYADGAFGIDEEIFELGIPILGICYGMQLITHKLGGKVLPAGEAGHREYGQSALRLRSESALFAGTPQEQLVLMSHGDAVTEIPEGFHLVGDSVDCPFAAMENTEKQFYGIQFHPEVRHSVYGNDILKNFAVNICGARGDWSMDNFIDMEIAKIRETVGDRKVLLGLSGGVDSSVVGVLLQRAIGDQLTCIFVDHGLLRKNEGDQVMDMLGGKFGLNIIRVDASKRFLDLLSGVEDPERKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEVVWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MSRA_METMP
Sequence: MKNIKTTVFGMGCFWGAEEVFRKINGVVSTEVGFMGGTIKNPTYGQVCRGKSGHIEVVKIDYDPEIISYDELLDLFWNNHNPTTPNKQGWDVGEQYSSYIFYFDDEQKLIAEKSLEKMQENTDLKIVTIIEKAGSFYPAEEYHQKYFMKKNNSILNF
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: TPIS_BDEBA
Sequence: MKKIFAANWKLFKSPKETREFFGQFKELAGKATGEVVFFPSAISLEAASESLKGTSIKFGAQNCYFQAQGAFTGENSAQVVKDLGGSYVLIGHSERRAIFGEGDALVADKVAFVQGLGLTPMLCIGETLQERESAKTFRVLETQLNLGLAKADKTKPVVVAYEPVWAIGTGKVATPEQVAETHTDVFNILKALGFETAPILYGGSVKPDNAAGLIKQPHVNGFLVGGASLEAKSFSEIASV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_BURMS
Sequence: MSGLPIATNLYFDAHFHRHGVKLLPNEFYTTREDMVLVTVLGSCVAACLHDPIGRIGGMNHFMLPDDGADPSAAASESMRYGAYAMEVLINELIKAGGRRERFEAKVFGGAAVLAGMTTINIGDRNADFVRRYLALERIRITAEDLQGVHPRKVAFMPHTGQAMVKKLRVQAPDVAAREAALAREAVDPHGERAPRVRPRVELFGTPAPKAQAKPRIELFGMRATQPATRKQEA
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: CYB_GENTG
Sequence: MTNIRKSHPLAKIINESFIDLPAPSNISAWWNFGSLLGVCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYIHANGASMFFICLFMHVGRGVYYGSFTFTETWNIGILLMFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGVVSDSDKIPFHPYYTIKDILGLLLLILVLMLLVLFSPDLLGDPNNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIVPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFITIGQLASILYFSIFLILMPISGIIENRLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SODM_MYCPA
Sequence: MAEYTLPDLDWDYAALEPHISGQINEIHHTKHHATYVKGVNDALAKLEEARANEDHAAIFLNEKNLAFHLGGHVNHSIWWKNLSPDGGDKPTGELAAAIDDAFGSFDKFRAQFSAAANGLQGSGWAVLGYDTVGSRLLTFQLYDQQANVPLGIIPLLQVDMWEHAFYLQYKNVKADYVKAFWNVVNWADVQKRYAAATSKAQGLIFG
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGB_SALG2
Sequence: MMNPLIIKLGGVLLDSEEALERLFTALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKDGLRVTPADQIGIITGALAGTANKTLLAWAKKHHIASVGLFLGDGDSVNVTQLDEALGHVGLAQPGSPKLINMLLENGFLPVVSSIGVTDDGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTASKAEQLIDQGIITDGMIVKVNAALDAARALGRPVDIASWRHAEQLPALFNGTPIGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS1A_RHORT
Sequence: MADPAFVPLRPIAIKDRSSIVFLQRGQLDVVDGAFVLIDQEGVRVQIPVGGLACLMLEPGTRITHAAIVLCARVGCLVIWVGERGTRLYAAGQPGGARADRLLFQARNALDETARLNVVREMYRRRFDDDPPARRSVDQLRGMEGVRVREIYRLLAKKYAVDWNARRYDHNDWDGADIPNRCLSAATACLYGLCEAAILAAGYAPAIGFLHRGKPQSFVYDVADLYKVETVVPTAFSIAAKIAAGKGDDSPPERQVRIACRDQFRKSGLLEKIIPDIEEILRAGGLEPPLDAPEAVDPVIPPEEPSGDDGHRG
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endonuclease Cas1 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: BH123_ARATH
Sequence: MGDHHDFINSGSWWKVSSSSSPSSSSSMRASSIESGGSAVFHDKLHHHSLATDHHLQMIGLGLSSQSPVDQWNQSLLRGDSKAETSFGVMLQENLNLDATSNANANTTSSTSSYQLQESDSSHHHQALWRDPQSDFKPQILTSGGNRGFFLDHQFSPHGSSSTDSSTVTCQGFAVDNSSNAMYAATTTTPNSSSGMFHHQQAGGFGSSDQQPSRNHQQSSLGYSQFGSSTGNYDQMASALPSTWFLRSSPPPKPHSPLRFSNNATFWNPAAAGNAGAPPPHDASSNFFPALQPPQIHPQSFDEQPKNISEIRDSSSNEVKRGGNDHQPAAKRAKSEAASPSPAFKRKEKMGDRIAALQQLVSPFGKTDAASVLSEAIEYIKFLHQQVSALSNPYMKSGASLQHQQSDHSTELEVSEEPDLRSRGLCLVPVSSTFPVTHDTTVDFWTPTFGGTFR
What are the official names of this protein?
Transcription factor bHLH123, Basic helix-loop-helix protein 123, AtbHLH123, bHLH 123, Transcription factor EN 63, bHLH transcription factor bHLH123.
What are the subcellular locations of this protein?
Nucleus.
Protein: B251_SSV1
Sequence: MVRNMKMKKSNEWLWLGTKIINAHKTNGFESAIIFGKQGTGKTTYALKVAKEVYQRLGHEPDKAWELALDSLFFELKDALRIMKIFRQNDRTIPIIIFDDAGIWLQKYLWYKEEMIKFYRIYNIIRNIVSGVIFTTPSPNDIAFYVREKGWKLIMITRNGRQPDGTPKAVAKIAVNKITIIKGKITNKMKWRTVDDYTVKLPDWVYKEYVERRKVYEEKLLEELDEVLDSDNKTENPSNPSLLTKIDDVTR
What is the function of this protein?
This protein may be involved in virus assembly.  Essential for virus function.
What are the official names of this protein?
Uncharacterized protein B-251.
Protein: PDXS_CORDI
Sequence: MTQETFTATTRVKRGLADMLKGGVIMDVVTPEQARIAEDAGASAVMALERVPADIRAQGGVARMSDPDLIEGIVNAVSIPVMAKARIGHFVEAQILESLGVDFIDESEVLSPADYVNHIDKWNFDVPFVCGATNLGEALRRITEGAAMIRSKGEAGTGDVSEAVKHLRTIRGEINRLRSMDEDQLYVAAKEIQAPYDLVREVAATGKLPVTLFVAGGVATPADAALVMQMGAEGVFVGSGIFKSGNPAARAAAIVKATTMYDDPAAIAEVSRGLGEAMVGINVADVPAPHRLAERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: HSLO_SHIDS
Sequence: MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INX19_CAEBR
Sequence: MFFHATLARSFISALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYWIPMYENVPDDHTAREEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQTLINAACDAQALLDYSDRQKAVEAITCNFVDNLDLQSPNGRIRARGWIARIKFSRFLSGQCISIVYSFTKLLYSVNVVAQFFILNACLKSSEFVFFGFQVLSDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEYKKLQKFEKDATVERLYTVIAFAPHLLDSFVSDFLKSDGILMLRMISNHAGDMIVVQLVRNLWQEYRERNWREFEEHEEMKDVEMRRIQGTRERIVIANPGQTKSFL
What is the function of this protein?
Structural component of the gap junctions that specifically coordinates left-right asymmetry in the developing nervous system.  Acts by forming gap junction network linking embryonic neurons and providing electrical coupling between cells, leading to promote or inhibit AWC signaling (By similarity).
What are the official names of this protein?
Innexin-19.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: SUCC_SHEHH
Sequence: MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKVFMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDAREAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNANLGRDVLASSGLDIIAAESLTDAAVKVVAAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: VP8_BAVJK
Sequence: MANRATSAFLDNPHPVGVNYVDEGSRQFVAVAELLASKLIASSRESDESNSDVPFVQAYSKFADDNPRHLRVKTGGKMANALTNVIRSYYSINAPAIVPQVEIDRLASKATVSGDMYNSYAVFNSVPIVEVLSPAQTTVSIVGSDRADVTMLNTGAGAANITFNFGQIAETVILKGSVPFQLARANQPMPAARFTYKLRPLDGPFIVVLPVGNPLVISATAATRIQVPLAFNKALVESGFQTAMNDGLFDAQNVNYYSSFDEFIIAQYHALDGINRVSTCVVLGLALQAYDQMRRALPVRRV
What is the function of this protein?
Self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers, with channels at each of its five-fold vertices.
What are the official names of this protein?
Intermediate capsid protein VP8, Virion protein 8, VP8.
What are the subcellular locations of this protein?
Virion.
Protein: AROC_ECO7I
Sequence: MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGIFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLEIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CASP9_HUMAN
Sequence: MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
What is the function of this protein?
Lacks activity is an dominant-negative inhibitor of caspase-9.
What are the official names of this protein?
Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
Protein: ISPG_ARATH
Sequence: MATGVLPAPVSGIKIPDSKVGFGKSMNLVRICDVRSLRSARRRVSVIRNSNQGSDLAELQPASEGSPLLVPRQKYCESLHKTVRRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLVQLNYNIPLVADIHFAPTVALRVAECFDKIRVNPGNFADRRAQFETIDYTEDEYQKELQHIEQVFTPLVEKCKKYGRAMRIGTNHGSLSDRIMSYYGDSPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMYVHGWDYPLHLGVTEAGEGEDGRMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRLANLGTKAAKLQQGVAPFEEKHRHYFDFQRRTGDLPVQKEGEEVDYRNVLHRDGSVLMSISLDQLKAPELLYRSLATKLVVGMPFKDLATVDSILLRELPPVDDQVARLALKRLIDVSMGVIAPLSEQLTKPLPNAMVLVNLKELSGGAYKLLPEGTRLVVSLRGDEPYEELEILKNIDATMILHDVPFTEDKVSRVHAARRLFEFLSENSVNFPVIHHINFPTGIHRDELVIHAGTYAGGLLVDGLGDGVMLEAPDQDFDFLRNTSFNLLQGCRMRNTKTEYVSCPSCGRTLFDLQEISAEIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGSPGKIDLYVGKTVVKRGIAMTEATDALIGLIKEHGRWVDPPVADE
What is the function of this protein?
Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.  Is essential for chloroplast development and required for the salicylic acid (SA)-mediated disease resistance to biotrophic pathogens.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), chloroplastic, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase, Protein CHLOROPLAST BIOGENESIS 4, Protein CONSTITUTIVE SUBTILISIN 3.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.