PharMolix/UniProtQA huggingface dataset:
Protein: OR1J4_HUMAN
Sequence: MKRENQSSVSEFLLLDLPIWPEQQAVFFTLFLGMYLITVLGNLLIILLIRLDSHLHTPMFFFLSHLALTDISLSSVTVPKMLLSMQTQDQSILYAGCVTQMYFFIFFTDLDNFLLTSMAYDRYVAICHPLRYTTIMKEGLCNLLVTVSWILSCTNALSHTLLLAQLSFCADNTIPHFFCDLVALLKLSCSDISLNELVIFTVGQAVITLPLICILISYGHIGVTILKAPSTKGIFKALSTCGSHLSVVSLYYGTIIGLYFLPSSSASSDKDVIASVMYTVITPLLNPFIYSLRNRDIKGALERLFNRATVLSQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 1J4, HTPCRX01, Olfactory receptor OR9-21.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUM1_XENLA
Sequence: MSVACVLKRKTVLWQDSFSPHLKQYPEGTLNHNMPVVLTSGPVGQQQPPQPPTHSALATGPHASPVGGSMGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNNSKHRWPTGDNIHAEHQVRSMDELNHDFQALALEGRAMGEQLLTGKKFWETDDSNKDGPKGIFLGDQWRESTWGASDHSVSQPIMVQRRPGQGFHVSSEVNSVLSPRSESGGLGVSMVEYVLSSSPGDSCLRKGAFGPRDTEGDENEKVDKKNKGVYEGDKLGDLKEEADSMDKCNGLPVQNGIDGDVKDFSRTPGNCQASASEVDLLGSIQNGSEGLVQLTNNNGAKPVEDFGGIESQSVQLDPMEHVGMEPLQFDYQGNQVPVDSGAAAVGLFDYNSQQQLFQRPNALTVQQLTAAQQQQYALAAAHQQHIGMFSAGLAPAAFVPNPYIISAAPPGTDPYAAGLAAAATLGPAVVPHQYYGVTPWGVYPANLFQQQAAAAAAASNSASQQNNPQSQQGQQQVLRAGGNQRPLTPNQNQQGQQTDQLVAAAAVNSALAFGQGLAAGMPGYPMLAPAAYYDQTGALVVNTGARNGLGGPVRLVAPASVIISQSAAQAAVAAAAASANGPAGTANGPFRQLNSQQPQGQPQPQGNQNLASSSFYGNSSMNSNSQSSSLFSQSSGQPGNSSLGFGSSGSLGATLSSALGGFGTAVANSNTNSGSRRDSLTGSSDIYKRTSSSLTPIGHSFYNGLGFSSSPGPVGMPLPSQGPSHSQTPPPSLSSHGSSTSLNLGGLTNGSGRYISAAPGAEAKYRSASSASSLFSPSSTLFPSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPPDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKSQVFALSTHPYGCRVIQRILEHCLPEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAMLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPAQRKIVMHKIRPHIATLRKYTYGKHILAKLEKYYMKNGMDLGPMCGPSNGII
What is the function of this protein?
Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets.  Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE).  Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of deadenylase complexes leading to translational inhibition and mRNA degradation (PubMed:12963108, PubMed:21098481).  Also mediates deadenylation-independent repression by promoting accessibility of miRNAs (By similarity).  Acts as a post-transcriptional repressor of ccnb1 mRNA during oocyte maturation (PubMed:12963108).
What are the official names of this protein?
Pumilio homolog 1, Pumilio-1, XPum.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule.
Protein: RNPA_CARHZ
Sequence: MNKCRFLSKNEEYRNIYQNGRSIASRYFVVYYLKNEDEKKLPSFGISVSKKIGKAVVRNRLRRRLKEALKRLCFEFLPGYDYVIIPRLSFKNDEFSVILEQLLYIIKLMKRSIDNA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: METK_CLOBB
Sequence: MRRLFTSESVTEGHPDKMCDQISDAILDAILTKDPNARVACETCTTTGLVMVMGEISTNCYVDIPKVVRETVREIGYDRAKYGFDCDTCSVMTTIDEQSADIAMGVDEALESKKGQKDEVEAVGAGDQGMMFGFATNETDAYMPLPIYMAHKLSRRLTEVRKDGTLDYLRPDGKTQVTVEYENNKPKRIDTIVISTQHGEEVSLEKIEKDIKEYVINAVVPTELLDSETRYFINPTGRFVVGGPQGDSGLTGRKIIVDTYGGYGRHGGGAFSGKDSTKVDRSAAYAARWVAKNLVAAGIADKLEIQLAYAIGVAKPVSIEIETFGTGKMPEDKIVEIVENVFDLRPGAIIRDLDLRKPIFKQTAAYGHFGRTDLDLPWERLNKIEEIKKYI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_BUCAT
Sequence: MENLNVDMLYIAVAIMVGLASIGAAIGIGILGGKFLEGAARQPDLVPLLRTQFFVVMGLVDAIPMIAVGLGLYMLFAIS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HLOAD_BPT4
Sequence: MIKLRMPAGGERYIDGKSVYKLYLMIKQHMNGKYDVIKYNWCMRVSDAAYQKRRDKYFFQKLSEKYKLKELALIFISNLVANQDAWIGDISDADALVFYREYIGRLKQIKFKFEEDIRNIYYFSKKVEVSAFKEIFEYNPKVQSSYIFKLLQSNIISFETFILLDSFLNIIDKHDEQTDNLVWNNYSIKLKAYRKILNIDSQKAKNVFIETVKSCKY
What is the function of this protein?
DNA helicase loader protein that participates in viral DNA replication, recombination, and repair (PubMed:10871615).  At the fork, required for loading of the replicative helicase onto DNA protected by the ssDNA-binding protein (PubMed:11459967, PubMed:7806533, PubMed:10871615, PubMed:22427673).  Coordinates simultaneous synthesis of leading- and lagging-strands (PubMed:11459969).
What are the official names of this protein?
DNA helicase assembly protein, Gene product 59, Gp59, Helicase loader, Helicase loading protein.
What is the protein family that this protein belongs to?
Belongs to the Tequatrovirus DNA helicase assembly protein family.
Protein: ISPF_PHOLL
Sequence: MRIGHGFDVHKFGGEGPIIIGGVRIPYEQGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGVDSRKLLREAYSRIREKGYRIGNLDITIIAQAPKMLPHIPQMRVNLAEDLQCHIDDINVKATTTEKLGFVGRKEGIACEAVALLVKE
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: TEC_BPP1
Sequence: MRHISPEELIALHDANISRYGGCRECLIRVGQRPLSGEFRPELPTKRSPTFSKSPPPTWWLQREGIYSMMPISVPR
What are the official names of this protein?
Protein tec.
Protein: GLMU_ECOUT
Sequence: MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQTEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNB_SHIFL
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLTIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTSLDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWKPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISSEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTGTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMLO1_MOUSE
Sequence: MVPYHIRQYQDSDHKRVVDVFTKGMEEYIPSTFRHMLMLPRTLLLLLGVPLALVLVSGSWILAVICIFFLLLLLRLLARQPWKEYVAKCLQTDMVDITKSYLNVHGACFWVAESGGQVVGIVAAQPVKDPPLGRKQLQLFRLSVSSQHRGQGIAKALTRTVLQFARDQSYSDVVLETSALQQGAVTLYLGMGFKKAGQYFMSIFWRLAGICTIQLKYSFPSA
What is the function of this protein?
May play a role in regulation of gastrulation.
What are the official names of this protein?
Probable N-acetyltransferase CML1, Camello-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the camello family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RPOA_DESOH
Sequence: MENELMYMNWQEMIQPDKIQVEAATPFYGKFICEPLGRGFGITIGNALRRIIISSLHGAAITSVKIDNVMHEYSTVEGVLEDVSEIILNLKEVRLKTSTAAAKTIRIDAAGPGVVTAGDIASPDGRVEILNPESHIATLSEGATLKMEMTVKVGRGYALAEANKDEETPVNTIPIDAMFSPIRRVNYVVGNSRVKQKTDFDKLTLEVWTDGSVLPEDAVAFAAKIMKEQMNVFINFDESAEPEHAGRKDDSGGKVFNENLYRSVNELELSVRSSNCLKNAEIDKLYQLVQKTESEMLKTKNFGRKSLNEIKELLAEMGLSLGMDLEGFVPPAEDNKEGE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL28_LEGPH
Sequence: MSRVCQVTGKRPMVGHKVSHANNKTKRRFLPNIQNHKFWVEEENRFVTLRLSTKGMRIIDKLGIKAVLDKIRAKGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MCPH1_HUMAN
Sequence: MAAPILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFNKQVTHVIFKDGYQSTWDKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAANMNEHLSSLIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMAKELQRQKTNLDDDVPILLFESNGSLIYTPTIEINSRHHSAMEKRLQEMKEKRENLSPTSSQMIQQSHDNPSNSLCEAPLNISRDTLCSDEYFAGGLHSSFDDLCGNSGCGNQERKLEGSINDIKSDVCISSLVLKANNIHSSPSFTHLDKSSPQKFLSNLSKEEINLQRNIAGKVVTPDQKQAAGMSQETFEEKYRLSPTLSSTKGHLLIHSRPRSSSVKRKRVSHGSHSPPKEKCKRKRSTRRSIMPRLQLCRSEDRLQHVAGPALEALSCGESSYDDYFSPDNLKERYSENLPPESQLPSSPAQLSCRSLSKKERTSIFEMSDFSCVGKKTRTVDITNFTAKTISSPRKTGNGEGRATSSCVTSAPEEALRCCRQAGKEDACPEGNGFSYTIEDPALPKGHDDDLTPLEGSLEEMKEAVGLKSTQNKGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLPGGYSGSVKNRPTRHDVLDDSCDGFKDLIKPHEELKKSGRGKKPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRTLNVLLGIARGCWVLSYDWVLWSLELGHWISEEPFELSHHFPAAPLCRSECHLSAGPYRGTLFADQPAMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKWVLDSITQHKVCAPENYLLSQ
What is the function of this protein?
Implicated in chromosome condensation and DNA damage induced cellular responses.  May play a role in neurogenesis and regulation of the size of the cerebral cortex.
What are the official names of this protein?
Microcephalin.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: LOLD_PSEPK
Sequence: MSDKAVLSCRNLGKSYDEGPESVQVLSGLNLELRAGERVAIVGSSGSGKSTLLNLLGGLDRPTQGSVWLAGEELSALGERARGLLRNRELGFVYQFHHLLPEFTAIENVCMPLLIGRTPIPEARERAEALLKRVGLGHRLNHKPAELSGGERQRVAIARALVNRPGLVMLDEPTGNLDHHTAQGIQELMQELSSASRTAFLVVTHDLNLARQMDRVLKLDDGHLVAI
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: O56B1_HUMAN
Sequence: MNHMSASLKISNSSKFQVSEFILLGFPGIHSWQHWLSLPLALLYLSALAANTLILIIIWQNPSLQQPMYIFLGILCMVDMGLATTIIPKILAIFWFDAKVISLPECFAQIYAIHFFVGMESGILLCMAFDRYVAICHPLRYPSIVTSSLILKATLFMVLRNGLFVTPVPVLAAQRDYCSKNEIEHCLCSNLGVTSLACDDRRPNSICQLVLAWLGMGSDLSLIILSYILILYSVLRLNSAEAAAKALSTCSSHLTLILFFYTIVVVISVTHLTEMKATLIPVLLNVLHNIIPPSLNPTVYALQTKELRAAFQKVLFALTKEIRS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 56B1, Olfactory receptor OR11-65.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRAAH_ACIAD
Sequence: MTTTVPFVTCDLLDDHTDKDIQVLTPSLDGRFFKSYGARKIFSGQIVTVKCFEDNSRVKELLATDGTGKVLVVDGGASMRCALMGDMIAESAVKYHWDGVVIYGCIRDVDALAELDLGIHALAAIPQKSNRQGIGEVGVNLYFGGVTFQAGCYIYADNNGIIVSKQKLID
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: Y3339_VIBCH
Sequence: MKKTLMAVGLAAVMSIPFAANAADYVIDTKGAHASINFKVNHLGYSYIKGRFNKFDGEFSYDPANIAASSVVVNVDTRSLDSNHAERDKHIRSADFIDASKYSTATFKSTEVVDKGNGQLEVKGDLTLHGQTKPIVINAEFIGAGQDPWGGQRSGFAGTTRLELKDFGIQVMGASSYVDMELHVEGVQK
What are the official names of this protein?
UPF0312 protein VC_A0539.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: EX7S_CLOB8
Sequence: MAKKESYEEMLTKLQDILSNLETDDLNLEESMKSYEEGVKLVNKIYKILDSYEAKISIIKDDKELEFSEDYGDK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUB1_ALKCK
Sequence: MSAQMALSLSGVHKSFGTTSVLKNVEFSLTKGECIAIVGKSGCGKSTLLRLLARLEQPTAGEVYIPNGDIVRMMFQEGRLLPWKTVLQNVMLGLKHDRKRKALEAIKSVQLEGKENEWPRALSGGQKQRVALARTLVHSPHVLLLDEPLGALDALTRREMQQLIEKIWLQRGFSVVLVTHDIDEAVTLADRVYVIENGSIANTYDINLPRPRKRSSYEFVETAEEILNRVLGVNATNGHLVSLSNIK
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYC_RHOPA
Sequence: MELRLYDTLTRDKRPFTPIDPANVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHLYGEAHVKYVRNITDVDDKINDRAARDYPGLPLNEAIRKVTEQTERQFHDDVDALGCLRPTVEPRATEHIGEMRSIIEKLVAGGFAYVEQDHVLFSPSAMNAANGVLPRYGSLANRSLDEMIAGARVDVAPYKRDATDFVLWKPSKPGEPSWPSPAGIATPGRPGWHIECSAMSWKHLGETFDIHGGGIDLVFPHHENEVAQSCCAFHTERMAQTWMHNGFLQVEGEKMSKSLGNFITIRELLATNKFGGRSWDGATLRLAMLKTHYRQPIDWTVDALHEAEKAILDWSDFAKDATPVRCDEVIAALTDDLNTPKMIAELHALRRAGKADELRGAMQLLGINPVVRAPVDLDATAKSLIEARTAARANKDWKESDRIRDELAAMGVVLKDGKDADGKSVTTWELAR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_PYRAB
Sequence: MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALLLGGVKTGF
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_CAMJE
Sequence: MAKKSMIAKAARKPKFKVRAYTRCQICGRPHSVYRDFGICRVCLRKMGNEGLIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: SIN1_XENTR
Sequence: MAFLDNPLIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKLYQSSVSGENSTQMQSNGGETQGYVYSQSVDITSSWDFGIRRRSNTAQKLERLRKERQNQIKCKNVQWKDRNTSHSAEELSSLFERKNFKERALNQGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVYLSMQTSQDKLLPMTVVTIANAKVHDLIGLICWQYTTEGREPKLNDNVDAFCLHIAEDDGEVDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLAAKQSLFVRINAAHGFSLIQVDSTNVTMRDILEKALKRRKGSQRNSGPQYRLEKQSQPNVPVDLDSTLENQNSLEFCLVRENSSRGEEPPEEETQIDIATVQDMLSSHQYKSFKVSMIHRLRFTTDVQLGISGEKVEIDPVTNQKTSTKFWIKQKPISIDSDVLCACDLAEEKSPSHAMFKVTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADYFAQKQRKLTRRTSFSFQKEKKPG
What is the function of this protein?
Essential component of the TORC2 complex, which plays a critical role in akt1 'Ser-473' phosphorylation, and may modulate the phosphorylation of pkca and regulate actin cytoskeleton organization.  May interact with a MAP kinase.  May act on Ras-regulated pathways (By similarity).
What are the official names of this protein?
Target of rapamycin complex 2 subunit MAPKAP1, TORC2 subunit MAPKAP1, Mitogen-activated protein kinase 2-associated protein 1, Stress-activated map kinase-interacting protein 1, SAPK-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the SIN1 family.
Protein: VIRR_RHIRD
Sequence: MSAGALNSAGAVMHSTRLRTNEVAVALPEEGDASLFFVGKIRTPWKSRSDTPRQGSELGPLCTLEISEPWAVALKGVEAYSRLEILYWLHESPRDIVLLSPADDGEIHGAFSLRAPVRPNPIGTSIVKVERVSGNSIVVRGLDCLDGTPLLDIKPDRSLSKPLAPVRKSFSIPAA
What are the official names of this protein?
Probable S-adenosyl-L-methionine-binding protein VirR, Protein VirR.
What is the protein family that this protein belongs to?
Belongs to the tRNA methyltransferase O family.
Protein: SSRP_SALTI
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANIGDSYVILKDGEAWLFGANFTPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKEREWQLDKARIMKNAGR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: IMDH_PYRAB
Sequence: MGKFAKKLERAIRGYTFDDVLLIPQATEVEPKDVDVSTQITPNVKLNIPILSAAMDTVTEWEMAVAMAREGGLGVIHRNMSIEEQVEQVKRVKKAERFIVEDVITISPEETVDFALFLMEKHDIDGLPVVENEKVVGIISKKDIAAREGKLVKELMTKDVITVPENIEVEEALKIMIENRIDRLPVVDKEGRLIGLITMSDLVARKKYKNAVRDENGELLVAAAVSPFDIRRAIELDRAGADVIVVDTAHAHNLKAIKAMKEMRQKVDADFIVGNIANPKAVDDLTFADAVKVGIGPGSICTTRIVAGVGVPQITAIAMVADRAQEYGLYVIADGGIKYSGDIVKAIAAGADAVMLGNLLAGTKEAPGKEVIINGRKYKQYRGMGSLGAMMKGGAERYYQGGYMKTRKFVPEGVEGVVPYRGTVSEVLYQLVGGLKAGMGYVGARNIKELKEKGEFVIITSAGLRESHPHDIIITNEAPNYPLEK
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: HN_NDVB
Sequence: MDRAVSQVALENDEREAKNTWRLIFRIAILLLTVVTLATSVASLVYSMGASTPSDLVGIPTRISRAEEKITSALGSNQDVVDRIYKQVALESPLALLNTETTIMNAITSLSYQINGAANNSGWGAPIHDPDFIGGIGKELIVDDASDVTSFYPSAFQEHLNFIPAPTTGSGCTRIPSFDMSATHYCYTHNVILSGCRDHSHSHQYLALGVLRTTATGRIFFSTLRSISLDDTQNRKSCSVSATPLGCDMLCSKVTETEEEDYNSAVPTLMAHGRLGFDGQYHEKDLDVTTLFEDWVANYPGVGGGSFIDGRVWFSVYGGLKPNSPSDTVQEGKYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRIQQAILSIKVSTSLGEDPVLTVPPNTVTLMGAEGRILTVGTSHFLYQRGSSYFSPALLYPMTVSNKTATLHSPYTFNAFTRPGSIPCQASARCPNSCVTGVYTDPYPLIFYRNHTLRGVFGTMLDSEQARLNPTSAVFDSTSRSRITRVSSSSTKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKNDGVREARSG
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.