PharMolix/UniProtQA huggingface dataset:
Protein: MRNC_CLOTE
Sequence: MRKYFLGEEFTKQDLKQMNPLVLAYIGDAVYEIFIRTYIISKNKDTCVNKLHKKTIQFVKADAQSYFIREIQKYLNEEEIKVFKRGRNTKSNTSAKNASIQDYRMATGFETVIGYLYLLNEDERLEEIMKLVINLYEESSQNEGENHGSKS
What is the function of this protein?
Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor.  Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.
What are the official names of this protein?
Mini-ribonuclease 3, Mini-3, Mini-RNase 3, Mini-RNase III, Mini-III.
What is the protein family that this protein belongs to?
Belongs to the MrnC RNase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_PPVSK
Sequence: MSTIVFGSFTCHLDAAIHQDNADRLAKAWTRPENRQVSNVHLLCRRAAKSLINTYESATASAWKGLEEKLQPMFAKREFSKTVTKRKGLRCFKESSEKFIEKKLKKQYKEERERFQFLNGPDAIVNQISVDKCEASVWVPFPHIIEKPSFTTPSMKKKVVFTKVRMSEASLQLFMRRVAANAKANGQKVEIIGRKRVVGHYTTKSRLTYFRTHVRHLDGSKPRYDLVLDEATKKILQLFANTSGFHHVHKKGEITPGMSGFVVNPMNLSDPMHVYDTDLFIVRGKHNSILVDSRCKVSKEQSNEIVHYSDPGKQFWDGFTNSFMQCKLRETDHQCTSDLDVKECGYVAALVCQAIIPCGKITCLQCAQKYSYMSQQEIRDRFSTVIEQHEKTVMDNYPQFSHVLAFLKRYRELMRVENQNYEAFKDITHMIGERKEAPFSHLNKINELIIKGGMMSAQDYIEASDHLRELARYQKNRTENIRSGSIKAFRNKISSKAHVNMQLMCDNQLDTNGNFVWGQREYHAKRFFRNYFDVIDVSEGYRRHIVRENPRGIRKLAIGNLVMSTNLAALRKQLLGEECIHFEVSKECTSKRGENFVYQCCCVTHEDGTPLESEIISPTKNHLVVGNSGDSKYVDLPTAKGGAMFIAKAGYCYINIFLAMLININEDEAKSFTKTVRDTIVPKLGTWPSMMDLATACHFLAVLYPETRNAELPRILVDHEAKIFHVVDSFGSLSTGMHVLKANTINQLISFASDTLDSSMKTYLVGGLEVDKCDEFKNVKLLIRSIYKPQIMEQVLKEEPYLLLMSVLSPGVLMALFNSGSLEKATQYWIARSHSLAAITAMLSALAAKVSLASTLNAQMSVIDEHAAVLCDSVFVGTKPYASYMMAVKTLERMKARTESDHTLNDLGFSVLRQATPHLVEKKLSPGVGAGLERIKLVGKVLCNLGIAAVAKTYTKTFHPERRSRFRRQVRHLRSVITWQPIQTPERRSSAEKRRRCLLHTPVDGKAILQSYRNFHKFSSKHSEDV
What is the function of this protein?
Allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding (By similarity).
What are the official names of this protein?
P3N-PIPO polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae P3N-PIPO polyprotein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma.
Protein: FIS1_KLULA
Sequence: MTNIHYLPELEDSYSALNSDQIEILRQQVLNEGGEISSIQSRFNYAWGLVRSTNKEDQMLGVKLLTDIYKESPMRRRECLYYLTIGCYKLGEYSTAKRYVDALVHHEPENKQALMLQTAVENKITSQGLKGIALISAGIAIGATTIGLLIRGRRR
What is the function of this protein?
Has a role in mitochondrial fission.  Has a role in outer membrane fission but not matrix separation (By similarity).
What are the official names of this protein?
Mitochondrial fission 1 protein.
What is the protein family that this protein belongs to?
Belongs to the FIS1 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: YCF4_PROM9
Sequence: MNSDLTSFDKIEQKIGGSRKTSNYIIGGMLTIGGIGFLLASISSYTGKDLLPLGNPSTLLFIPQGIIMGAYGVVANLLNFYLWYMVYINFGSGSNSFNKSSKSVEIKRKGLFKDIDVKLNFDEIKSVKLDISEGFNPRRRIALVLKGRKKPLPLSGAGELKPLLQVEEEGARLAKFLNVNLEGLK
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: YOHB_SCHPO
Sequence: MNRLNFQSLLWKFGQKRFYYRPWIRIENIKPTPLWKPITFAVGVGSATFYTANYLDKRRKNYPKSSYGFPIPQTSSRSLVLSIIGINVGVFALWRAPRFSHLNRFLQKYAVMNPIFINMPSMIVSAFSHQSGWHLLFNMVAFYSFAPAIVDVFGNNQFVAFYISSILFSNVASLLHHRLRFGTKVTPGSLGASGAIYAIAAATSYFFPNASVSIIFLPFIPIKIGVALLGLMAFDAWGLISRGFSSFANFTLIDHAAHLGGGIFGWLYAKYGYSTYNRSTRPRPPSLSKPFFSRSVSF
What are the official names of this protein?
Uncharacterized protein C13E7.11.
What is the protein family that this protein belongs to?
To yeast YGR101w.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ZN534_HUMAN
Sequence: MALTQGQLSFSDVAIEFSQEEWKCLDPGQKALYRDVMLENYRNLVSLGEDNVRPEACICSGICLPDLSVTSMLEQKRDPWTLQSEVKIINNPDGRECIKGVNTEKSSKLGSSAGNKSLKNQHGLTLQLHLTEWQPFQAVRNIYGCKHVEKSISDNSSVSPVQISFFSVKTHIFNNYRNDFLFSTLLPQEQKVHIREKPYGCNEHGKVFRVSSSLTNRQVIHIADKTYKCSDCGEIFSSNSNFAQHQRIHTGEKPYKYNECGKVFNQNSHLAQHQKIHTGQKPYNNKECGKVFSHHAYLAQHRKIHTGEKPYKCSECGKAFSVCSSLTAHLVIHTGEKPYDCKECGKVFRHKSSLTTHQTVHTGERPYKCNECGKGFSRIAFLARHRKVHTGEKPYKCNECGKVFIGNSRLARHRKIHTGGRRYKCNECGKAFRTCSDLTAHLLIHTGEKPYECIDCGKVFRHKSSLTYHCRIHTGEKPYKCNECGKVFSQNSNLQRHRKIHTGEKLYKCNECGKVFRQNSHLAQHRDIHTGEKPYSCNECGKVFRRNSHLVRHRNVHTGEKPYSCNECGKVFSRNSHLARHRNIHTGEKPHSCNECGKVFSRNSHLARHRKIHTGEKLYKCNECSKVFSRNSRLAQHRNIHTGVKPYSCNECGKVFSKNSILVQHCSIHTREKP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 534, KRAB domain only protein 3.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TATA_MYCS2
Sequence: MGGLQPWHWVIVIAVFVLLFGAKKLPDAARSLGKSMRIFKSEIKEMQAESKGDEPKPATPIASERVDTTAPEQQSTDRHTA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NFUA_ACIBS
Sequence: MSTENTNTAVAEEIPNLLITPSAQEYLHELLAKQNTPGIGVRIFVEHPGTPRAECCMAYSAPEEVVPTDYKQDYPDFPAYIDAPSIPYLLDAVIDYNKDRFGGQLTFRAPNSKVPRVGPDASIEERITYVLQAEINPGLAGHGGNCSLVEVQDDPEHGLTAVLKFGGGCQGCSAIDVTLKQGVETTLKEHILELQRVVDQTDHTQAEGAYFK
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: THIM_THEP3
Sequence: MKKELLKILREKKPLVHHITNIVTVNDCANITLAIGALPVMAHALEEVEEMVSAADALVLNIGTLTNEQVEAMIKAGKAANRLKVPVILDPVGAGATKLRTQSSKKILEEVKISVIKGNSAEISILAGKGGKIRGVESQSGADDISEAAKDLANAYNVVVAVSGVTDIITDGKRIAYVKNGHPMMGTVTGTGCMLTSVVASFCGVCEDYFAATVEAFVAFGIAGERAAQSSNVKGPGSFKVTFFDEIYNLTPEIIEKDKKVEYE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: RL3_CUPTR
Sequence: MSLGLVGRKVGMTRIFTDDGEAIPVTVVEVGDNRVTQIKTDETDGYTAVQVTFGARRASRVTKPLAGHLAKAGVEAGEIIREFRIDAAKAAELQAGGSLSVDLFEVGQKIDVQGVTIGKGYAGTIKRYHFASGRATHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHLGDVTRTVQNLEIAKIDAERKLLLVKGAIPGSKNGKVIVTPAVKAKAKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PERA2_ARMRU
Sequence: QLNATFYSGTCPNASAIVRSTIQQAFQSDTRIGASLIRLHFHDCFVDGCDASILLDDSGSIQSEKNAGPNANSARGFNVVDNIKTALENTCPGVVSCSDILALASEASVSLTGGPSWTVLLGRRDSLTANLAGANSAIPSPFEGLSNITSKFSAVGLNTNDLVALSGAHTFGRARCGVFNNRLFNFSGTNGPDPTLNSTLLSSLQQLCPQNGSASTITNLDLSTPDAFDNNYFANLQSNNGLLQSDQELFSTLGSATIAVVTSFASNQTLFFQAFAQSMINMGNISPLTGSNGEIRLDCKKVDGS
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase A2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
Protein: MURQ_SYNE7
Sequence: MDPSLSDRGHLLTEQANPASQALDQLSPLELVDLFNQEDQHCLAAVAQAREAIAQAIEYAAQAIARGGRLFYIGAGTSGRLGVLDAAECPPTFCSDPEQVQGILAGGSAAMFRSSEGLEDRAEDGAVAIAEYQIGPRDFILGITAGGTTPYVHGALEAARSAGAKTGFLACVPADQVAIAVDVDIRVPVGPEILAGSTRLKAGTVTKMVLNQISTGAMVRIGKVYGNRMVDVAVTNRKLEDRALRILSDLLSIDRQQAAALLGANERSVKQALLQHWTGLEPAEAAALLTEHQGHLRAAVTAFSSLR
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: ACCD_PHAAO
Sequence: MKKYWFNSMLSNKKLEQKCGLSKSMDGLDALGHTSGSEETIRKDADKKIPSWDSYSFSNIHYLNSLFDRRNLWSLISDHTFLVRNSNGDTYSVYFDIENQIFDIDNASSFLSELPSYLKSGSNNSNYYYSYYSMYDTQSNWNNHINSCIDSYLRFEISLNSDIYSDIDSYISSFICTESTSSIENCTESTSSIENGNSSIKTSSSYFNRIEKSNDFDLNTKYKQLWVQCENCYGLNYKKFFSSKMNICEYCGYHLKMSSSDRIELFIDPGTWEPMDEDMVSIDPIEFHSIDPIEFHSEEEPYIDRISFYQTKTGLTEAVQTGVGQLNSIPIAIGVMDFQFMGGSMGSVVGEKITRLIEYATNRSLPVIIVCASGGARMQEGALSLMQMAKISSASYDYQSNKKLFFVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLKKTVPDGLQVAEYLFHKGLFDPIVPRNPLKGVLNELFQLHGFLPLNQD
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: XERC_PSEFS
Sequence: MERQLDAYCAHLRNERQVSPHTLEAYRRDLNKVLAYCEKQQISSWKALDIQSLRSLIARLHQAGQSSRSLSRLLSAVRGLYHYLNREGLCDHDPANGLSPPKGERRLPKTLDTDRALQLLDGAVEDDFLAHRDQAILELFYSSGLRLSELTGLNLDQLDLADGLVQVLGKGSKTRVLPVGRKAREALQLWLPLRLLTNPADDAVFVSQQGRRLGPRAIQVRVKAAGERELGQNLHPHMLRHSFASHMLESSQDLRAVQELLGHSDIKTTQIYTHLDFQHLATVYDSAHPRAKRIKGGDS
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_MACCJ
Sequence: MKITIITVGKLKEKYWKMAVDEYVKRLGAYSKIELVEVADEKDSDNMSEKDIEIAKRKEAERILSKVKDDSFVYTLEILGKQLDSVQLAKEMEQKMNTGKSHLTFIIGGSNGLHQNVMDRSNYALSFSKMTFPHQMMKVILLEQIYRGFRIMKGQAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIL_PIG
Sequence: QAVLGAGLPCNTTTSPIIKVCASGMK
What are the official names of this protein?
Acetyl-CoA acetyltransferase, Acetoacetyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: P3A2_STRPU
Sequence: MMISEDISEPSSPDTPFDDSDLLNSSMTDDVSAQLAASGPIGVRAAAAIATGKKRKRPHSFETNPSIRRRQQTRLIRKLKATIDEYATRVGQQAVVLTCTPGKHDGNFKVFGAAPLENIMRNLKGIVLQDLDNALAQRAPQPSNENSDLYELPPLVIDGIPTSVNKMTQAQLRAFIPLMLKYSTGRGKPGWGKESCRPVWWPSDLPWANVRSDVRSEDEKRKVSWTHALVTIVINCYKHHGRDDLLPEFIEDKCKEIEASQNQVASLPTATLLPSHAVVHTINNPDGTVSLIQVDTGATVATLADVTQVQQLTNLQTLQQVRLQPLQIQHALGNQQAEATQAVQTLAEVAAAQGGDGELTEGQTVTTLPEGTQLVLASDGSLQAINDGTAQGIVIPASVYQTVVAGDGQPIQIANVNIAQQSGGGTTMAAIKNAVMQSQPIPSQVATLVVNAASHDQHT
What is the function of this protein?
Transcriptional regulator that interacts with specific sites in the control region of the cyIIIa actin gene.  Also binds specifically to similar target sites located in the regulatory region of the SM50 gene.
What are the official names of this protein?
DNA-binding protein P3A2.
What is the protein family that this protein belongs to?
Belongs to the NRF1/Ewg family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL19_WIGBR
Sequence: MNLINIIENSQKKSNITKLFSGDIVKINIWVLEGNKKRIQIFEGIIIAIKNKGISSSITVRKISNGEGVERMFPLHSPIIESIIVNRHSLVRKSKLYYLRNKKGRSSRIKQRLKK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: KAD_ELUMP
Sequence: MIIVLLGAPGAGKGTQSVLVAEKYGLKHISTGDLLREEIANNTELGKQAKKLIDGGNLVPDEMILGLLKNAFLNRGKGVVLDGFPRTLSQAEMMHPIVKGLAEKLSAVINIKLSEDEITQRIVLRRQCKNCGNIFNLRFIKNFDGKCPKCGSTDIYQRADDNEESAKNRINVYHSQTEPVVGFYKNKTYYKEVDGSKNKEEVFEEISKFINRKK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM44_YARLI
Sequence: MFTPTDISGEPSAVGTQWTPYLSHPVDFGAQHFLEAMLNVISQPNINSSVIMRADIISDSLNMMPNIMGTDKANEGFIFDTHEGPVDDDKKDTDKDKNTPVPPNLQDYEPRQVEVTPCPVKRVIVRRIIPRNPQNDFSVNQTCIVHSDKPLWDSDGKETSEGAKIAISYISHHDHPKSCPYYLPCVKAVLLYFDGSAISVYYEKYTDYELSAEQEERCGRIALHLLHTVFRHSSGQKAGYKKRVHHDMIIDRIKFQDRYIYLKQKYAHSLVSSWVESTDPRKHVFEDLAIAAFLIELWGQMYKNKDDIYFYDLGCGNGLLVNILIKEGYVGEGVDARARKSWQTYEPEVTQKLLEKIVVPTVLLDQMVGQAQYLPPHAAEKRLAEANGLATDPRVFQTAGLPENAFLIGNHSDELTCWIPLMDRPFMVIPCCSHALSGEKKRFPPTSSDPEEKSTYRSLVGHVEQLSSKIGWQVEKEYLRIPSTRNAAVIGRTRVEPQMNIFEILYSEGGGEGWVERARDLCAKSPRNH
What is the function of this protein?
Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
What are the official names of this protein?
tRNA (uracil-O(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TRM44 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCHS_VIBA7
Sequence: MKLSNEDLCKLNKFWLYCEENQYFNVGYPESAAFDYSILEKFMKFSINNCGDWREESNYKLNSFEFEKEVMRFFSQLFKIPYNDSWGYISNGGTEGNMFSCYLAREIFPTAYIYYSEETHYSVDKIVRLLNIPARKIRSLPSGEIDYQNLVDQIQKDKQKNPIIFANIGTTMRGATDNIQRIQQDLASIGLERNDYYIHADAALSGMIMPFVEQPHPYSFEDGIDSISVSGHKMIGSPIPCGIVLAKRHMVDQISVEVDYISSRDQTISGSRNGHSALFMWTAIKSHSFVDWQGKVNQCLNMAEYTVQRFQEVGINAWRNKNSNTVVFPCPSEPVWRKHSLANSGSVAHIITMPHLDGPDKLDPLIEDVIYDLLPNYNILNVSGQN
What are the official names of this protein?
Histidine decarboxylase, HDC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: TOLIP_SALSA
Sequence: MSTTISTQRGQVYIGELPQDFLRITPTQQQQQVQLDAQAAQQLQYGGSLGTVGRLSITVVQAKLAKNYGMTRMDPYCRVRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHVTIPEGLREGSVVDEWYSLSGRQGDDKEGMINLVMSYANMPAGMHMSPPVVLMPTVYQQGVGYVPIAGVPTVYNQGMVPMGMPAAPTVAAQEAPCSEEDLKALQDMFPNLDREVIRTVIEAQQGNKDAAINSLLQMTEEL
What is the function of this protein?
Component of the signaling pathway of IL-1 and Toll-like receptors.  Inhibits cell activation by microbial products.  Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates.  The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity).  In a complex with TOM1, recruits ubiquitin-conjugated proteins onto early endosomes (By similarity).  Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P) (By similarity).
What are the official names of this protein?
Toll-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the tollip family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_ACIBC
Sequence: MKQQAKSRKPQQPEYIFQVETLSHEGRGIAHYGSHPDHPADKHGKKVFIRYALPGETVKAQITHEAKRLEEAEMVALLAEPSANRVEAVCPHYGICGGCSMQHIHPDEQICLKQNVLQSHLQHFAGIQPEQWLEPIRSLQSDYRRRARIGVRYLPKQDRLILGFREHHSNRLTSIHTCSVLDKKLSDSLPELRNLLQSLKGKAHIGHVELAKGDYETSLLVRHIEKLNNADVNQLRQFALHKGWQLYLQPKGPESLRRIDEEQGAMRLHYALNAFDVNFAFSPLDFTQVNATVNEQMVQLACELLQLQQGERVLDLFCGLGNFSLPLARCVGAKGQVVGVEASEEMVQRATDNAKRNNLVQASFFSQDLTKDFSHHSWANQGFDALLIDPPRAGAYEIMQYVPNFGAKRIVYVSCNPATLARDAGVLVQHGYQLKKAAVMDMFTHTEHVESIALFEKIQEIND
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: HEMA_INBF8
Sequence: DRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPKCLNCTDLDVALGRPKCTGTIPSAKASILHEVKPVTSGCFPIMHDRTKXRQLPNLLRGYEHIRLSTHNVINAEKAPGGPYKIGTSGSCPNVTNGNGFFATMAWAVPKNDNNKTATNSLTVEVPYICTEGEDQITVWGFHSDNETQMVKLYGDSKPQKFTSSANGVTTHYVSQIGGFPNQAEDGGLPQSGRIVVDYMVQKSGKTGTITYQRGILLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKER
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RECA_CUPTR
Sequence: MDDKKAGAGVSAEKQKALAAALSQIEKQFGKGSIMRLGDGEVEKDIQVVSTGSLGLDIALGVGGLPRGRVVEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEHALDVNYASKLGVNVGDLLISQPDTGEQALEITDALVRSGSIDLIIIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGSIKKGDDVIGNETKVKVVKNKVSPPFREAFFDILYGQGISRQGEIIDLGVDAKIVEKSGAWYSYNGEKIGQGKDNAREYLRENPDIAAEIENKVRAALGVVAMNPTAAAVAATVED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2R46_GORGO
Sequence: MITFLPIIFSILIVVTFVIGNFANGFIALANSIEWFKRQKISFADQILTALAVSRVGLLWVLLLNWYATELNPAFYSIEVRITAYNVWAVISHFSNWLATSLSIFYLLKIANFSNLIFLRLKRRVKSVVLVILLGPLLFLVCHLFVINMNQIIWTKEYEGNMTWKIKLRSAMYLSDTTVTILANLVPFTLTLISFLLLICSLCKHLKKMQLHGKGSQDPSMKVHIKALQTVTSFLLLCAIYFLSVIMSVWSFESLENKPVFMFCEAITFSYPSTHPFILIWGNKKLKQTFLSVLWHVRYWVKGEKPSSS
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).  In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 46, T2R46.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
Protein: ATPF1_DANRE
Sequence: MWDGEKMAAAMVQMSCLYRGMLAVRNHGIRPLIPGLVPSHFRAFSMKKEPELEENPYYSKYEEKIRKLRSSKPQEYESRLEKRTELKTEPLGRSRQAEFVKYMEKELDKRGKDGDGGFTKDKTLGSILNLEMVQEKSGAEITELWMQYFSKKDTISAVIPSSTFDVIFGRAKSCPTFLYALPQNEGYEFFVGQWAGNELHFTSLINVQTMGENAPSQLILYHYTDLQKDKDIVLMTAEMDSKFVTVHQAQCLANQVQLFYGSQRLETFRLVETFNHKPEEFKHMAVIAELEQSGIGPAVTTK
What is the function of this protein?
May play an essential role for the assembly of the mitochondrial F1-F0 complex.
What are the official names of this protein?
ATP synthase mitochondrial F1 complex assembly factor 1.
What is the protein family that this protein belongs to?
Belongs to the ATP11 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GLPE_PSEMY
Sequence: MSEFKRISPQQAQELRSNGAVVVDIRDPQSFALGHISGSRHLDNHSLHDFITHADLDAPLIVSCYHGNSSQSAAAYLAGQGFSEVYSLDGGFELWRATFPSETAQGSEE
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_METTP
Sequence: MFLDFMSEVEGILKEGLDRCGLSVPLENSLDLSPHADLSTTIAFRLSPVLRKDPKDVAAEIYNSMGSPSRWVDRAELVGPYINFYMSRNFLDNVVTKAQGEDAWWGRRSGSVVVEHTSANPDGPLHVGHIRNSVIGDTIVRILRRAGYNVEAQYYVNDMGRQTAMVVWGCDHLDLDDSKPDHAIARVYIAAHKIMNEKPELSAEVDELMRRYESRDPEIVKKFQRAARYAISGIERTLHRMNIHHDSYKWESEFVWDGSVDEILEMLERTGRTVLKDGALQLDLSEEGFEKSLVLRRADGTTLYTTRDLAYHKWKAENYERVVEVLGADHKLISAQLRTALRMLGIGEPEVVIFEFVSLPDGSMSTRRGKFISADELLDEVEKQAYLEVTKRRPEMDEEFRRDVAGKVAVGAVRYDIVRVSADKATTFDWKTALDFEKLSAPFIQYSHARACSIINKAGELDEFDPGLLRDDYEIALIKKIAEFDLVIERAARELKPHQLATYARELAERFNLFYRYDPVLDAKPVELRNARLGLVRASRNALSATLDTLGIDAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.