PharMolix/UniProtQA huggingface dataset:
Protein: HIS5_SULTO
Sequence: MKATLINYGVGNLFSIKAGLERVGFNVKISFLPEGDEDVIVLPGVGAFSAVSSYLNSMKDKFNELRERGVKFLGVCLGMQVMFDEGTEGGLSKGLGWFKGKVDKIHSNVKLPHIGWDKLFVNKDSCNLTEGLDGKYVYYVHSYVAYTNDYVAYSEYGIKYPAIVCNDFAVGTQFHPEKSSVTGKIFLRNFYSWVKR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRHA_METTH
Sequence: MSERIVISPTSRQEGHAELVMEVDDEGIVTKGRYFSITPVRGLEKIVTGKAPETAPVIVQRICGVCPIPHTLASVEAIDDSLDIEVPKAGRLLRELTLAAHHVNSHAIHHFLIAPDFVPENLMADAINSVSEIRKNAQYVVDMVAGEGIHPSDVRIGGMADNITELARKRLYARLKQLKPKVDEHVELMIGLIEDKGLPKGLGVHNQPTLASHQIYGDRTKFDLDRFTEVMPESWYDDPEIAKRACSTIPLYDGRNVEVGPRARMVEFQGFKERGVVAQHVARALEMKTALARAIEILDELDTSAPVRADFDERGTGKLGVGAIEGPRGLDVHMAQVENGKIQFYSALVPTTWNIPTMGPATEGFHHEYGPHVIRAYDPCLSCATHVMVVDDEDRSVIRDEMVRL
What is the function of this protein?
Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.
What are the official names of this protein?
Coenzyme F420 hydrogenase subunit alpha, 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit alpha, FRH.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
Protein: TRMB_SACD2
Sequence: MQPEFKKKSIRSFVIRGGRMTEGQKNAFDKWWPHYGVSLFDGPINPAELFGRSAPLVLEIGFGMGDSLVDMAIADPDSDFIGIEVHPPGVGRLINRAGTEGVPNLRCYMADANDVLSDCIPDGSLDRLQLFFPDPWHKKKHNKRRIVQPEFVEKIRAKLKIGGHFHMATDWEAYAEHMMEVMTAAPGYENIAGGSEFAPQPSYRPTTKFERRGENLGHGVWDIIFSRSL
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: HISZ_CLOBK
Sequence: MEKWNKHIPEGMKDILFKESNIKLNIEDQLRKVYKYSGFSEIISPTIEFYDVFNSNIQAIPQEKMYKLFDNLGRVLVLRPDMIAPIGRITGTKMKECTYPLRLCYTANIFRVNEKLNGKRGEIAQSGIEIIGTNGIKSDVDSIVTAINALLSLGLKNFKIELGEAGFFQALTENMEIKEENLKKLKEIIRNKNYVALKKFLDEISSKYSKEDFELIKNLPKLFGDIKIIEKAKALTKNKKALRSLDDIHNIYKSIENIGLEAYISIDLGMVQNIDYYTGVIFKGYVEEVGDSILSGGRYDNLIQHFGIELPATGFAINVDDIMIALKKQNTMSMDKDKKVLIFYKEEFLRKAYDFMQELKMKKIICELSLLDDDKEILLYSKKKGIDFIIGFMGEEKLFVKDLKSDKIAFLKKDEIENLLML
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCED_SALTI
Sequence: MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSDVECSMSFAIDNQRLAVLTGDAVVTVSLECQRCGKPFTHQVHTTYCFSPVRSDEQAEALPEAYEPIEVNEFGEIDLLATVEDEIILALPVVPVHDSEHCEVSEADMVFGELPDEAQKPNPFAVLASLKRK
What is the function of this protein?
Plays a role in synthesis, processing and/or stability of 23S rRNA.
What are the official names of this protein?
Large ribosomal RNA subunit accumulation protein YceD, 23S rRNA accumulation protein YceD.
What is the protein family that this protein belongs to?
Belongs to the DUF177 domain family.
Protein: RUSC1_HUMAN
Sequence: MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLVDANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVSVYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDSNCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTEKTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWRSDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPIAEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELWFSSLQEDAGLLSLLYLPTGFFSLARGGCPSLSTELLLLLQPLSVLTFHLDLLFEHHHHLPLGPPQAPAPPGPPPALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTPGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSLVL
What is the function of this protein?
Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network (PubMed:30262884).  Signaling adapter which plays a role in neuronal differentiation (PubMed:15024033).  Involved in regulation of NGF-dependent neurite outgrowth (PubMed:15024033).  May play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins (By similarity).  Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK (PubMed:15024033).  Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway (PubMed:19365808).
What are the official names of this protein?
AP-4 complex accessory subunit RUSC1, New molecule containing SH3 at the carboxy-terminus, Nesca, RUN and SH3 domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Early endosome. Postsynaptic density. Golgi apparatus. Note=Translocated to the nuclear envelope upon stimulation with NGF (PubMed:15024033). Associated with membranes and microtubules (By similarity).
Protein: FADA_SALTI
Sequence: MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQTLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLSRLHGISREMQDQFAARSHARAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIRPETTVEALSTLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVPASKLALKKAGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARISTTLINLMERKDAQFGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.  Involved in the aerobic and anaerobic degradation of long-chain fatty acids (By similarity).
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_XANOM
Sequence: MTPRLRLQPESVGIGMTSQRVRDRLVERLREAGIHDEATLNAMQTVPRHLFIDEALASRAYEDTALPIGHGQTISQPWVVARMTEAVLQVTPTKVLEVGTGSGYQGAILAALGLEVYTVERIGDLLRQARKRFRHLGMNVRSKHDDGRIGWHEHGPYDAIVVTAAAPALVDALVDQLAVGGRLVAPVGGASSQSLVQLTRGADGTIEQQVLAPVTFVPLLSGMLD
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIP1_MYCTO
Sequence: MGMRLSRRDKIARMLLIWAALAAVALVLVGCIRVVGGRARMAEPKLGQPVEWTPCRSSNPQVKIPGGALCGKLAVPVDYDRPDGDVAALALIRFPATGDKIGSLVINPGGPGESGIEAALGVFQTLPKRVHERFDLVGFDPRGVASSRPAIWCNSDADNDRLRAEPQVDYSREGVAHIENETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRAALGDDKLTYLGYSYGTRIGSAYAEEFPQRVRAMILDGAVDPNADPIEAELRQAKGFQDAFNNYAADCAKNAGCPLGADPAKAVEVYHSLVDPLVDPDNPRISRPARTKDPRGLSYSDAIVGTIMALYSPNLWQHLTDGLSELVDNRGDTLLALADMYMRRDSHGRYNNSGDARVAINCVDQPPVTDRDKVIDEDRRAREIAPFMSYGKFTGDAPLGTCAFWPVPPTSQPHAVSAPGLVPTVVVSTTHDPATPYKAGVDLANQLRGSLLTFDGTQHTVVFQGDSCIDEYVTAYLIGGTTPPSGAKC
What is the function of this protein?
Key immunomodulatory virulence factor, which promotes survival in host macrophages and modulates host immune responses.
What are the official names of this protein?
Serine protease Hip1, Carboxylesterase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cell envelope. Cell membrane; Lipid-anchor.
Protein: EFTS_CLOBH
Sequence: MISAKMVKDLREKTGAGMMDCKKALTECDGDLEKAVEVLREKGLAAAAKKSGRVAAEGIVSTYISEDMKNGSIVEFNCETDFVSVNELFVELANNLSKQAAFSNVSTAEELLEEKYIADESKLVKDVITELIAKLGENMNLRRIAKLSVDKGVITSYIHGGGRIGVLVKLACEKEDAKLAEIAKDVAMQVAATNPLFLNRDGVDTDTLEKEKEIYRVQALNEGKPEKVVEKMVMGRINKYYKENCLVEQLWVKNGDYTITKYLQEQSKEIGADITVEAFVRYEKGEGIEKKEEDFAEEVQRQMNQGK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOO2_SCHPO
Sequence: MKDDQLIDWIHERYEEQKSANRLAGRFRFLGLETKYSIISIISGIFIGLTAALLNALASLLNSFREGYCTVNILFDKQTCCSTLTEDYECQEFFFWRNNHSVFVSCLIYVSVSVGFAFIATTLGYVVAPAARASGIPTIKAILSGYKYPDMNVFFSIKTLCSKSLAVCFSVASGLWVGKEGPFVHIATNIIYLVERIAPSLADSEIFTRQLLAAAMASGIAASFNAPVGGVIFALEQLASSSFPSLFTGSIWYEFLCSASSVVALQLIRSWHTDVGYLSYVSLDRRWSYKDTLPFIFISILCGCLGSVLIYLNMKFASKTKGFSKISNVFFVIFLSLITSLTAYAILGESELLFNPMELFPQVINSCSPSSSTVLCETTFWVTAIVLFTSALLGLLLTSATFGAAIPTGIIVPSLAIGACIGRAVGTLLKSRFPSLAGTSIYGVIGSIAFLSSTTRLVVALVVILFELTGALNIALPLMLATLISKWVSDSIIETSIYDAWIQFRNIPYFPSSNSLKFSIPLNFPVRSPEQLVRLPIRSCSIEELERAMHDSSQSFFVVLKNDTEFFEGFISRNKVSELLNRRPMSSNMQTTDNTGLDPLRSASAPVDSTFDLFDYIHPTTFTLNYDTPPVLMLKLFKDAGITNLALLNHGKLHGVLTKIDIIEYAKKCKTHTGNTYSELPTGVTYETDIFNRADD
What is the function of this protein?
Voltage-gated chloride channel.
What are the official names of this protein?
Uncharacterized chloride channel protein C887.02.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYFA_CUPTR
Sequence: MSQDLDQIVADAQAAFAAANDNATLENEKARFLGKTGALTELLKGLGKLDPETRKSEGARINQVKQQVEAALQARRQALADALMNARLAAEAIDVTLPGRAVARGSLHPVMRTWERVEQIFGSIGFDVADGPEIETDWMNFTALNNPDNHPARSMQDTFYVDGRDSEDKLLLLRTHTSPMQVRYARMHVEKYAGKAMPPIKVICPGRTYRVDSDATHSPMFNQVEGLWIGEDVSFADLKGVYTDFLRKFFERDDIQVRFRPSYFPFTEPSAEIDMAFGNGKWLEISGSGQVHPNVLRNMGLDPERYIGFAFGSGLERLTMLRYGINDLRLFFEGDVRFLRQFA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_XANOM
Sequence: MSRVCQVSGKRVQTGNNVSHANNRTRRRFLPNLHERRFWVASENRWVKLRVSAHALRTIDKNGIDAVLKELRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PIN_CHAFM
Sequence: MSLGCITPLASAMVGPKLVRPLIHHNPLFHHKPLNRPYLQTKIPLRSRVAQNPINMALITTDEGITRRIGNHHPNLWDDDFIQSLSKAYEAPSYGERAEKLIKDVRDMFNALPLHSSSADDLIQHLSLVDSVERLGIDRHFQNEIKTALDYVYRYWSDAGIGCGRESTHADLNTTALGFRILRLHRYSVSSDVLQQFVLRDGPFLDSNNQPNEDDIKNILNLFRGSLIAFPGENVLDDAKSFTMTYLKQVLPKISNLNLSREIKFNLEYGWHTNVPRLEARTYIDIYGEDSSWASKSINNIFYTKLLELAKLDFNIIQSLQQQELQILSRWWMESDLGKLDFARHRHVEYYLWAATGCIEPKYSAFRIGFAKLSALVTYLDDMYDTYDFDEIKIFTKAIKRWDASIIKGLPEFMKVAFKAFDEAVKDMAQEAKKTQGRDTLDYARKAWEVYIDAYMKEAEWLATGYMPSLEEYLENGKVSAGSRVVTLQPILSLDVPLSDDILKEIDYPSRFDELLCLTLRLRGDTRTFKAEADRGEVVSCITCYMKDHPGSNEEDALNYLNSLIDERLKELNWEYLKTDNVPIISKGNAYNLSKGLQLLYKERDGFTVFSIETKNFIYRMMIGSIPI
What is the function of this protein?
Monoterpene synthase involved in the biosynthesis of volatile compounds (Ref. 1).  Mediates the conversion of (2E)-geranyl diphosphate (GPP) into alpha-pinene (Ref. 1).
What are the official names of this protein?
Alpha pinene synthase, chloroplastic, Cf-Pin.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYSC_PSEAI
Sequence: MIEHPGFVLWFTGLSGAGKTTIAVALENQLRARGIRIERLDGDTVRQSLTKDLGFSKEDRDKNIERVTFVAKLLSRNNVAVLSSFISPYAATRDHVRGETTNFIEVFVDAPLETCIERDVKGMYKKAIAGEIPNFTGISDPYEAPANPDIHVKTHEQTLEESVQTIIRRSSHGWNRTNTFPLKSRPNPPHRHKSKSSRAGEPFISPVFVLSIIA
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Probable adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: OTC_STAAW
Sequence: MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDNIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_STRSV
Sequence: MNKEREARKYLRLLSVRRCRHIATIVELVREVIEPAILAPYELVDIEYGKMGGDYVLSVFVDKPEGITVNDTADLTDIISPLLDQIKPDPFPEQYFLEVTSPGLERPLKTKEQLADAVGSYIHVSLYKAVDKQKVFEGTLLSFEEDVLHMEYLDKTRRKEVEIPYSLVSKARLAVKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCOT1_RAT
Sequence: MAALKLLSSGLRLCASARNSRGALHKGCACYFSVSTRHHTKFYTDPVEAVKDIPNGATLLVGGFGLCGIPENLIGALLKTGVKDLTAVSNNAGVDNFGLGLLLRSKQIKRMISSYVGENAEFERQFLSGELEVELTPQGTLAERIRAGGAGVPAFYTSTGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFRGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAGTTVVEVEEIVDIGSFAPEDIHIPKIYVHRLIKGEKYEKRIERLSLRKEGEGKAKSGKPGEDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNMTVHLQSENGVLGLGPYPLKDEADADLINAGKETVTVLPGASFFSSDESFAMIRGGHVNLTMLGAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSSKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKGVFDVDKKNGLTLIELWEGLTVDDIRKSTGCDFAVSPNLMPMQQIST
What is the function of this protein?
Key enzyme for ketone body catabolism.  Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate (acetoacetate), and produces acetoacetyl-CoA.  Acetoacetyl-CoA is further metabolized by acetoacetyl-CoA thiolase into two acetyl-CoA molecules which enter the citric acid cycle for energy production (By similarity).  Forms a dimeric enzyme where both of the subunits are able to form enzyme-CoA thiolester intermediates, but only one subunit is competent to transfer the CoA moiety to the acceptor carboxylate (3-oxo acid) and produce a new acyl-CoA.  Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity).
What are the official names of this protein?
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial, SCOT, 3-oxoacid CoA-transferase 1, Somatic-type succinyl-CoA:3-oxoacid CoA-transferase, SCOT-s, Succinyl-CoA:3-oxoacid CoA transferase.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CCMA_LEGPN
Sequence: MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERRSIKKDLCTYQKQLCFVGHRSGINPYLTLRENCLYDIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIIRKIQEHRAKGGAVLLTSHQDLPLNKADYEEYHL
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BOP1_DROAN
Sequence: MTKKLTLKRKGKEPEPTNEVAASSEASDNEEEEDLLQAVKDPGEDTTDDEGIDQEYQSDSSEDLEFESDEEGNYLGRKKGDGSSEEEDDDGDEEGEEEDEEEDDSEDGESADDGDEEKPTTSKQNKSEDEPSSSKVSKKTQPPTKDLVKRDPSHPEYHDSDTSDEEDIRNTVGNIPMHWYDEYKHIGYDWDAKKIVKPPQGDQIDEFLRKIEDPNFWRTVKDPQTGQEVLITDEDIALIKRIISGRIPNKDHNEYEPWVEWFTSEVEKMPIKNVPDHKRSFLPSVSEKKRVGRMVHALKMGWMKTTEEVEREKQAKRGPKFYMLWETDTSREHMRRIHDPVSAPKRDLPGHAESYNPPPEYLFDERETKEWLKLKDEPHKRKLHFMPQKFTSLRAVPAYSRYLRERFLRCLDLYLCPRAKRVKLNIDAEYLIPKLPSPRDLQPFPTIESLVYRGHTDLVRSVSVEPKGEYIVSGSDDKTVKIWEIATGRCIRTIETEDVVRCVAWCPNAKLSIIAVATGNRLLLINPKVGDKVLVKKTDDLLAEEPSSDVIESERIKAAVQWATAEPAEQEKGVRVVINHFKPIRQVTWHGRGDYLATVMPEGANRSALIHQLSKRRSQIPFSKSKGLIQCVLFHPVKPCFFVATQHNIRIYDLVKQELVKKLLTNSKWISGMSIHPKGDNLLVSTYDKKMLWFDLDLSTKPYQTMRLHRNAVRSVAFHLRYPLFASGSDDQAVIVSHGMVYNDLLQNPLIVPLKKLQTHEKREDFGVLDVNWHPIQPWIFSTGADCTIRLYT
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: INSL3_MOUSE
Sequence: MRAPLLLMLLALGSALRSPQPPEARAKLCGHHLVRTLVRVCGGPRWSPEATQPVETRDRELLQWLEQRHLLHALVADVDPALDPQLPRQASQRQRRSAATNAVHRCCLTGCTQQDLLGLCPH
What is the function of this protein?
Seems to play a role in testicular function.  May be a trophic hormone with a role in testicular descent in fetal life.  Is a ligand for LGR8 receptor (By similarity).
What are the official names of this protein?
Insulin-like 3, Leydig insulin-like peptide, Ley-I-L, Relaxin-like factor.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLSA_CLOB6
Sequence: MNRLFKTIIENNRKWVSEGKVASYIPELSKMDKNLLGISVCTLGGEEYWEGDAEVKFTIQSISKIVTLMLAIIDNGEDYVFSKVGMEPTETAFNSIVNLEAKESHKPINPMINAGAIVVASMVAGKDSDEKFDRILKFTRKISGNNNIDINLNVYKSEKETGHRNRALAYFMKSTGALKGNVEEILDVYFKQCSIEITCKDLARIGVMLANDGVSPYTGDRIVPRHVARIVKTIMVTCGMYDASGNFAVHIGIPAKSGVGGGIVACAPRRMGIGVLGTALDEKGNSIAGTKILEELSKQLDLSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: RL7_CHLT3
Sequence: MASIDELVEEIGKLTLTEASELVKALEEKFGVSAAPVMVAGGAMPGAAGAAEAPAEEKTEFDVVLKSAGASKINVIKVVRAATGLGLKEAKAVVDEAPSTVKEAMPKADAEKLVKELKEAGAEAEMK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: VP6_ROTH1
Sequence: MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMIITMNGNEFQTGGIGNLPIRNWNFDFGLLGTTLLNLDANYVETARNTIDYFVDFVDNVCMDEMVRESQRNGIAPQSDSLRKLSGIKFKRINFDNSSEYIENWNLQNRRQRTGFTFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANTQQFEHIVQLRRVLTTATITLLPDAERFSFPRVINSADGATTWYFNPVILRPNNVEVEFLLNGQIINTYQARFGTIIARNFDTIRLSFQLMRPPNMTPTVAALFPNAQPFEHHATVGLTLRIESAVCESVLADASETMLANVTSVRQEYAIPVGPVFPPGMNWTDLITNYSPSREDNLQRVFTVASIRSMLIK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: YOBD_SALTI
Sequence: MTITDLVLILFIAALLAYALYDQFIMPRRNGPTLLSIALLRRGRIDSVIFVGLVAILIYNNVTSHGAQMTTWLLSALALMGFYIFWIRTPRIIFKQRGFFFANVWIEYNRIKEMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLIENQ
What are the official names of this protein?
UPF0266 membrane protein YobD.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YEE2_SCHPO
Sequence: MAAPANASSKKDHVIPVLLNECSIDSPSFRASMYYLGNQIKAFNEWSHDFLCCCNKFIESIMAIEPIVASMSLNAMPSNVASGFFDPDYATTALLHGQDLFRSSYMVQLQQAKNLRKFIVAPLDLFRDSKVKPLLQLNDRFKAEQAKYDAEVLRYSSLGHSKDLSQMRDEAKSLYEARKSYFTVALQYVVRVTSFRSSIDFIVIESICKFSIETFRLTDRLHESNRHINDQLIRLLSYETKLKESYPSLKRIVSNVFDRIEKEILKRVQPPTNLDAYRFDPQQICQTNATKRQGWLLRNISSSKADNKAIWRKYWFFVDNGYVGYLINDANGGVFESEKIGVLLCKFSVLPSNHRKFCFQIKTKSVSYILQAETHMEMLEWGSVINNAREHCINSGISANRILSPTLPSFSAKATSIINPQVNGRSNSTGKIGKNYRPRRTYSGRLLCGPNNYEVSTIMRSPTISTVPPPKYLSNSINGAKFLNPLAPWTLVNAPLITNLTHETITSLLDQEAFFHGNSPCALLANFWGSVNYGHVLERQNVYIEDLSNPSYKRLAREIHIEKLPSELKLRNAEFRGIFGESEASTVLFVCRVCSKREDQIRMPGRMYCTMKGIYIYYNINGLVLIEHFPISSILNVKQFASTKCDYFYMNIQNIGTVRFRLYLDSSKALTDRLNVLLCNYIADKPNSSIQLLSCIKRLNDDVKRFERGGDDNALKSYGVQPSQEDLLIRRGRSSRALTNLINKNESNDSFMEDLRDFKIAMLPKETVQVVRSHHLDDIVFDRVYNVSTKALFHIVFGDRSTVLSGAYNLHGVDDVEFLPWGKDPKTNLSRRYINYKVYNYDQEGQCQSYHYEDCQIMDVRNDYHLYIMTWLHHSWTLPYRDYFKIVTKTSISHLRREKSRLLISVGLEWIVKPFAISKVIEAECRKLAIKYIKTEVNFLEKATRRARNQPLIAIINQYGRVGDYNESMVYRRKIPFNCELKNLSIIDIIRNNWWLFLQGLAIDLLKLPWAVFHIFLRYLFSHSFLVIIFACSVILNLSLMFCFGAKYWDERQNNKFVGQVFDEFKNIETSARYVYMKDVDDLLVGLPTYLHPNVTYPSECLQSFALKSSPQKSHWLRKRNYIAEKRKKILENLASLNYYEYIIHEDAVYQYIQQELLGCDKAREFDLYPPSMQRYCDSCTQDWRNRTLFFGKDTLATRLLTLETVENADYAA
What are the official names of this protein?
Uncharacterized PH domain-containing protein C19A8.02.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.