PharMolix/UniProtQA huggingface dataset:
Protein: POLG_ECHO9
Sequence: GAYTGMPNKKPKVPTLRQAKVQGPAFEFAVAMMKRNASTVKTEYGEFTMLGIYDRWAVLPRHAKPGPSILMNDQEVGVLDAKELVDKDGINLELTLLKLNRNEKFRDIRGFLAREEVEVNEAVLAINTSKFPNMYIPVGQVTDYGFLNLGGTPTKRMLMYNFPTRAGQCGGVLMSTGKVLGIHVGGNGHHGFSAALLRHYFNEEQ
What is the function of this protein?
Major viral protease that mediates proteolytic processing of the polyprotein (By similarity).  Cleaves host EIF5B, contributing to host translation shutoff (By similarity).  Cleaves also host PABPC1, contributing to host translation shutoff (By similarity).
What are the official names of this protein?
Genome polyprotein.
What is the protein family that this protein belongs to?
Belongs to the picornaviruses polyprotein family.
What are the subcellular locations of this protein?
[Viral protein genome-linked]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Protease 3C]: Host cytoplasm.
Protein: PUR7_LACP3
Sequence: MNKTTLLYTGKAKQVYATDDPDVLWMAYTNQATALNGEKKAQIAHKGELNRAISTLLFKELTAAGIPTHYLDSPDSTTMIVKKAAMLPLEVVVRNYASGHFVTKFNVKPMMKLDPPIHEYYYKSDELGDPFMNEAQIFALHEATPEQLKQVHALTDRINTYLTQRFAAIGITLVDFKLEYGTLKDGTLVLADELSPDNFRLVDQQTGASLDKDVFRQNRGPLTPVYEEVLSRLQEKGAAHV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: MED4_BOVIN
Sequence: MAAASSGEKEKERPGGGLGAAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQSGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAISSEEIIKYAHRISASNAVCAPLTWVPGDPRRPYPTDLEMRSGLLGQMNNPSTNGVNGHLPGDALAAGRLPDVLAPQYPWQSNDMAMNMLPPNHSHDFLLEPPGHNKENEDDVEVMSTDSSSSSSDSD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 4, Mediator complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HXB1_CHICK
Sequence: MDNTRMNSFLEYAICNRGTGAYHHLEQSSPSFPSCSGSPSSDTFHGEGAYGAGGSPVAAAHLPPQSPGFFPAPPGAPSLRGRCPERRVPNPKLQPRLRHHQLYLGQQDADAVYFQAAGYSSSTGPHLGSLAEGYCGAVGQYQQQQHLYGQEQPSYLPGVYGNLSPSLNEDKDPACPSEPCPNASRARTFDWMKVKRNPPKTAKVSEYGLLGQPNTIRTNFTTKQLTELEKEFHFNKYLTRARRVEIAATLELNETQVKIWFQNRRMKQKKREKEGLAPPAASRSAKEASEASDQSNCTSPEASPSSVSS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Acts on the anterior body structures.
What are the official names of this protein?
Homeobox protein Hox-B1, Ghox-lab.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Labial subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1945_MYCTU
Sequence: MRSDTREEISAALDAYHASLSRVLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACEEELGGTLRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTATAAAQREGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRPDHLHGLATQLMDWLHPDGNFSDQERARKRGITMGKQEFDGMSRISGLLTPELRATIEAVLAKLAAPGACNPDDQTPVVDDTPDADAVRRDTRSQAQRHHDGLLAGLRGLLASGELGQHRGLPVTVVVSTTLKELEAATGKGVTGGGSRVPMSDLIRMASNAHHYLALFDGAKPLALYHTKRLASPAQRIMLYAKDRGCSRPGCDAPAYHSEVHHVTPWTTTHRTDINDLTLACGPDNRLVEKGWKTRKNAKGDTEWLPPAHLDHGQPRINRYHHPEKILCEPDDDEPH
What are the official names of this protein?
Uncharacterized protein Rv1945.
What is the protein family that this protein belongs to?
Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.
Protein: ATPB2_CHLL3
Sequence: MDTADHHQRYGRVARIRGSVVDVRFERHLPPIHTILETGKDREVKIEVLTQLDDRHIRGIALTGTEGLCRAMAVLDTGMPLRAPVGKQILSRMFDVFGRPIDRGAPPPDVEWRGVHRMPPPLGRRSTRSEVFETGIKIIDLLSPLERGGKAGLFGGAGVGKTVLLTEMIHNMVHRHHGVSIFCGIGERCREGEELYRDMRDAGVLDSMVMVFGQMNEPPGSRFRVGLAALTMAEYFRDDQHEDVLLLIDNIFRFIQAGSEISGMMGQMPSRLGYQPTMGTELSQLEERIANTGTGAITSIQAVYVPADDFTDPAAVHTFSHLSASLTLSRKRAGEGFFPAIDPLQSGSKMTAPSIIGRRHYDLSRQIRRVLAQYSELKDIIAMLGLEQLSAEDRKLVARARRLERFLTQPFFTTEQFTGIEGRMVSLNDTIDGCERILRDEFADYPESSLYMIGTVAEARKNNAVHAP
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: METK_PHOV8
Sequence: MGYLFTSESVSEGHPDKVADQISDAVLDKLLAFDPSSKVACETLVTTGQVVLAGEVKTKAYVDLQRIAREVINRIGYTKSEYMFEGNSCGVFSAIHEQSADINRGVEREDPMNQGAGDQGMMFGYATNETENYMPLSLDLAHKLLMVLAEIRREGKVMTYLRPDAKSQVTIEYDDNGKPVRIDTIVVSTQHDEFVTPADSSKEAQLKADEEMLAKIRQDVIEILMPRVIAGIHNEEVLALFNDRIVYHVNPTGKFVIGGPHGDTGLTGRKIIVDTYGGKGAHGGGAFSGKDPSKVDRSAAYAARHIAKNMVAAGVADEMLVQVSYAIGVARPINIYVNTYGRSNVKLSDGEIAKKIDELFDLRPKAIEERLKLRNPIYEETASYGHMGREPKVVTKTYESMYHEAKTLEVELFTWEKLDYVDKIKEAFGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_DICNV
Sequence: MEKLLGYRDLNMTPREIVEELDRHIIGQKHAKRAVANALRSRWRRKQVAEPLRSEITPKNILMIGPTGVGKTEIARRLAKLAEAPFIKVEATKFTEVGYVGRDVDSIIRDLVETSIKLEKNRAKERVKSKAREAALERVLDVLVPRKKQTAWTGEEEIDPARKMYRERILREEMNDTVIEIETNQSMSANVEIMTPPGMEEMSSQLSEMFKSFGREKKTKRKMTIAKALIQLAEEEAEALVSHEEIKSAAIDNAEQNGIVFIDEIDKVARRSDVGGADVSREGVQRDLLPLVEGCTISTKYGMIKTDHILFIASGAFHLAKPSDLIPELQGRLPVRVELDALTADDFKRILTEPDASLIKQYTALFATEQLHLEFTEDGINKIAEIAYHVNKTTENIGARRLHTLIERLTDSLSFDAADRRDGDRVIIDAAYVEKTLGEISNNEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUPC_DICDI
Sequence: MINIEDISKSSNQSEEKQLKSTSSKTKYPFAAKSLFKGSNNITPYYLSTSNTFQCVASESIQTWLLSDDGHIFTSSGNFVLDVSSGGYFVELVQLNSNSKTQIWTIDTTNNKIQNQGNGKYLDIDNLNICVAPLNGNATQKWTTFRRAPIPTGNWGYFQSKKLDSNNNYWGLSVLNNSTSYNTSVVMNKVQAKSIGQIWQMTNDGHILSRLDGNLVLDIGPSINGSKTNYYLNTNVYKANDLMQQWGINENNQIFNQYYPNLCIGFVGELGVDSTVNCVLAQPTSAGNINFQWIANPTYSLNQIVSEVPEPFPAYTSGDLLASYQYLSNIATNGYTDDIRSLYTSINVSLEIFYVNVTNATCPSSIHSTEDFSNVQNQIKNELTYAINVRLVFDNYSDFYSKLFSQGSTNLTNLANLINVDMSSDQVVNGDYTDAITSVFYAIISEIPIGGSIIANIGESAVEFGELDAESNDSGPSTYQVTLSKLYDHLNENYENEMANAQSMKNTILQDWGMMSKTFALCFLPTNNPSSLNINGLDFQKISTIASIAYQTAMIQMLLPTNYQIYFTPAGYYAPVSSDDYSYTDSTGTYIMAEIDNCNSHPPKALTDKLWNNGVSKQEVFTSSYGWNLATSVTYYNMVGKYSGMFKLSFPTVKNFTSVPMQFVMTNGSDRVGTFNVKTHFAGLASTYYYSGALGHHYYDIAVIDINGNKVANFTVDNNLEALEGSYVSIKTNSLVVQPGYVVGNPTCNQGSFSQGFAASILIPIYKSN
What is the function of this protein?
May play an important role in stabilizing and/or regulating the cell membrane during Ca(2+) stress or certain stages of development.
What are the official names of this protein?
Calcium up-regulated protein C.
What is the protein family that this protein belongs to?
Belongs to the cup family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: RPPH_PHOPR
Sequence: MIDGDGYRPNVGIVICNSHGQVFWARRYGQHSWQFPQGGIDEGETPEQAMYRELYEEVGLTKKDVRILASSRHWLRYKLPKRLVRWDSKPVCIGQKQKWFLLSLECDESRVNMQRGSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRALKEFAAIAMPFKERKERKLKRYKSKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: H2A6_ORYSI
Sequence: MDVGVGGKAAKKAVGRKLGGPKKKPVSRSVKAGLQFPVGRIGRYLKKGRYAQRVGTGAPVYLAAVLEYLAAEVLELAGNAARDNKKNRIIPRHVLLAIRNDEELGKLLAGVTIAHGGVLPNINPVLLPKKTAEKADKPAKASKDKAAKSPKKQARS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Probable histone H2A.6.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NDPA_HAES1
Sequence: MSIIVNQIVLHQLVKTSQDENTVQLKTHLRDELLPITAETEQMMLQLHQEYHNKTKAYGVFQETSNFAQILNRTLENDIDFLAFSHQSAELLRQELGKYSFANDGTLILCQYNFLATDYLFIALLDSRYSMLVDENLEIKQTHYLDITQFDIACRINLTELHLDAKSTRYLTFIKGRVGRKIADFFMDFLGAEEGLNPQVQNQCLLQAVSDYCQQADLTKEQTQAVKKQVFDYCKGQINVGEEIVVRELSANIPTLNEQSFVDFAVSQNYGLEENIPPVRTALKSLTKFSGSGKGITLSFDAELLNSRIFWDEATDSLTITGLPPNLRDQLQRQTKE
What are the official names of this protein?
Nucleoid-associated protein HS_0228.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HGD_MOUSE
Sequence: MAELKYISGFGNECASEDPRCPGSLPKGQNNPQVCPYNLYAEQLSGSAFTCPRNTNKRSWLYRILPSVSHKPFESIDQGHVTHNWDEVGPDPNQLRWKPFEIPKASEKKVDFVSGLYTLCGAGDIKSNNGLAVHIFLCNSSMENRCFYNSDGDFLIVPQKGKLLIYTEFGKMSLQPNEICVIQRGMRFSVDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPVAWYEDRRVPGGYTVINKFQGKLFACKQDVSPFNVVAWHGNYTPYKYNLENFMVINAVAFDHADPSIFTVLTAKSLRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIKGHYEAKQGGFLPGGGSLHSAMTPHGPDADCFEKASKAKLEPERIADGTMAFMFESSLSLAVTKWGLKTCSCLDENYYKCWEPLRSHFTPNSRSPTEPK
What is the function of this protein?
Catalyzes the conversion of homogentisate to maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: H4_MOUSE
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SCTR_RAT
Sequence: MLSTMRPRLSLLLLRLLLLTKAAHTVGVPPRLCDVRRVLLEERAHCLQQLSKEKKGALGPETASGCEGLWDNMSCWPSSAPARTVEVQCPKFLLMLSNKNGSLFRNCTQDGWSETFPRPDLACGVNINNSFNERRHAYLLKLKVMYTVGYSSSLAMLLVALSILCSFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHKVGCKLVMIFFQYCIMANYAWLLVEGLYLHTLLAISFFSERKYLQAFVLLGWGSPAIFVALWAITRHFLENTGCWDINANASVWWVIRGPVILSILINFIFFINILRILMRKLRTQETRGSETNHYKRLAKSTLLLIPLFGIHYIVFAFSPEDAMEVQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWRQWHLQEFPLRPVAFNNSFSNATNGPTHSTKASTEQSRSIPRASII
What is the function of this protein?
Receptor for secretin (SCT), which is involved in different processes such as regulation of the pH of the duodenal content, food intake and water homeostasis (PubMed:25332973, PubMed:12403838).  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:9506976, PubMed:12403838).  Upon binding to secretin, regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate (NaHCO(3)) from the ductal cells of the pancreas (By similarity).  In addition to regulating the pH of the duodenal content, plays a central role in diet induced thermogenesis: acts as a non-sympathetic brown fat (BAT) activator mediating prandial thermogenesis, which consequentially induces satiation.  Mechanistically, secretin released by the gut after a meal binds to secretin receptor (SCTR) in brown adipocytes, activating brown fat thermogenesis by stimulating lipolysis, which is sensed in the brain and promotes satiation.  Also able to stimulate lipolysis in white adipocytes.  Also plays an important role in cellular osmoregulation by regulating renal water reabsorption.  Also plays a role in the central nervous system: required for synaptic plasticity (By similarity).
What are the official names of this protein?
Secretin receptor, SCT-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURA_YERP3
Sequence: MDKFRVQGRTRLSGEVTISGAKNAALPILFAALLAEEPVELQNVPKLKDIDTTIKLLSQLGTKIERNNGSVFVDASAVNEFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHITGLEQLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTVIENAAREPEIVDTANFLNTLGAKISGAGTDRITIEGVTRLGGGVYRVLPDRIETGTFLVAAAISGGKVVCRQTRPDTLDAVLAKLREAGADIEVGDDWISLDMQGKRPKAITFRTAPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICYGVEQLSGAQVMATDLRASASLVLAGCIAEGVTIVDRIYHIDRGYERIEDKLRALGAKIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1819_HISS2
Sequence: MPAVEKIGDNLRLRIFLQPKASKDHLIGLYDNALKISITAPPIDGQANAHLLKFLSKTFKVAKSQIILEKGELSRHKQILIPHPKSIPPVVANLLIETT
What are the official names of this protein?
UPF0235 protein HSM_1819.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: MEP50_XENLA
Sequence: MSKGSAWGRPVTAPACMEVQIGAVRYRRDGALLLAASSLSSRTWGGSIWVFKDPEGAPNESLCTAGVQTEAGVTDVAWVSEKGILVASDSGAVELWEILEKESLLVNKFAKYEHDDIVKTLSVFSDGTQAVSGGKDFSVKVWDLSQKAVLKSYNAHSSEVNCVAACPGKDTIFLSCGEDGRILLWDTRKPKPATRIDFCASDTIPTSVTWHPEKDDTFACGDETGNVSLVNIKNPDSAQTSAVHSQNITGLAYSYHSSPFLASISEDCTVAVLDADFSEVFRDLSHRDFVTGVAWSPLDHSKFTTVGWDHKVLHHHLPSEGRTENLIATKAED
What is the function of this protein?
Non-catalytic component of the 20S prmt5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones.  Required for normal prmt5 methyltransferase activity.
What are the official names of this protein?
Methylosome protein 50, MEP-50, WD repeat-containing protein 77.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Enriched on chromatin.
Protein: CH60_ACIF2
Sequence: MPAKQVAFAEHAREKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELADKFENMGAQMVKEVASQASDEAGDGTTTATVLAQAIIREGLKAVIAGMNPMDLKRGIDKSVIVVVEELKKQSKPCKTQKEVAQVGTISANSDDSIGKIIAEAMEKVGNEGVITVEEGSGLANELDVVEGMQFDRGYLSPYFVNNQDKMVAELENPYILLHDKKISSIRDMLPILEQVAKSSRPLLIVAEDVEGEALATLVVNTMRGIIKVAAVKAPGFGDRRKAMLEDMAILTGGRVVSEEIGMKLESTTLADLGQAKKIVIDKENTTMIDGAGQQSEIKARVEQIRRQMEDASSDYDREKLQERVAKLAGGVAVIKVGAGSEMEMKEKKARVEDALHATRAAVEEGIVPGGGVALVRARHALEGFKTANHDQDMGVAIIRRAIEEPLRQIVANAGGEGSVVLNKVVDGKDGYGYNAATDEYGDMFEMGVIDPTKVTRTALQKASSIAGLMITTEAMVTELPKKDDKSGGDMGDMGGGMGGMGGMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_HELPY
Sequence: MAKQEYKQLPKRAEVHSATEQFKDTVKTSLGLDLFKGLGLTIKEFFSPSVTIHYPMEQLPLSPRYRAVHNLQRLLDSGSERCIGCGLCEKICTSNCIRIITHKGEDNRKKIDSYTINLGRCIYCGLCAEVCPELAIVMGNRFENASTQRSQYGSKSEFLTSEQDAKNCSHAEFLGFGAVSPNYNERMQATPLDYVQEPSKEESQEETPTNPESNKGDENV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ACEK_BURPS
Sequence: MNHFPKLLSSQIGFDVAQTILENFDRHYRIFREAAVEAKDLFERADWHGLQRLARERITSYDDRVRECVELLEDEYDAENIDNEVWPQIKLHYIGLLTSHRQPECAETFFNSVCCKILHRAYFNNDFIFVRPAISTEYIENDEPAAKPTYRAYYPGSEGLAATLERIVTNFQLNPPFEDLERDIACIMQAIHDEFGAFDEAVNFQIHVLSSLFYRNKTAYVVGRIINGDRVLPFAVPIRHARAGILALDTVLLRRDQLKIIFSFSHSYFLVDMNVPSAYVQFLRSIMPGKPKAEIYTSVGLQKQGKNLFYRDLLHHLSHSSDRFIVAPGIKGLVMLVFTLPSFPYVFKMIKDHFPPPKDTTREQIMAKYLLVKRHDRLGRMADTLEYSSVALPLARLDDALVRELEKEVPSLIEYEGENLVIKHLYIERRMVPLNLYLQNGSDAEIEHGVREYGNAVKELMQANIFPGDMLYKNFGVTRHGRVVFYDYDEIEYLTDCNVRRVPPPRNDEDEMSGEPWYTVGPHDIFPETYAPFLLGDPRVREHFLAHHADFFDPQLWQDSKDRLLRGELPDFFAYEPALRFCIRYPERFAPGDAADGGKLAAA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_LEGPL
Sequence: MSLYIGLMSGTSMDGIDAALLELPSNQLIHGITKQYSDDVRRNLDNLIMGNHLTLASICQLNTLIGREFAEAVRQLLIEIKVHPKEIQAIGSHGQTVCHDTSGSIPYTLQLGCGHTISSLTGITVVADFRTRDLVNGGQGAPFAPLYHQQIFSKVNESVAVVNIGGIANVTFIAKNQMTRGWDIGPGNCLMDAWIYKNKGALFDKSGVWASQGEVIHPLLEYLLQDPFFHLDSPKSIGKEYFSLSWLQKHLKPDYTPADIQATLLALTAHTIAETILNESGEIKQLYLCGGGAHNTHLKENLARLLPGIAVKSIVELGISPDYLEAMMFAWLAAQTINQIPVNLTSITGAKSIAILGAVYPIIKSY
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: FAZ1_TRYB9
Sequence: MALLNVISENPLTLQPGQVIAFDHLANGEHWQWALGTVVSSDKHVVVVEQWAVNEGSCETLKHNISSEIQKEMKRMGVFQEQLSSARDKLAAIRSENEDRVSAARAVFEDAKARVASVDEVHMREVTSQACPSPVAVEVLKCVLALAQNDPTVTNCSTWDDIRMEYRRPNAIADFISADITGKTYPNAEEICSSLNEQRLSSLAASRDSEAISSLHHWVLSALAYQEAYCRLTTDTRVQEQNDAIANCIAGMKGCRLKVMKLKEELERGGTPTFGGQLTSFTKTSVQLKAPLSSVISIVGVDPSAQDCVLTDDEVGLILDKAEQTRLQINDHFSHLSNSYMEAMAELHCLSMYTSELEERRLNLQERFVFSLFTNAGKTNAPRRERIETDVGLRSVEAPRGDSANNIKDLQEIIKELSSHDERWMYRNEPTVTTKHRKSYPGREWSKVVERKPEELLSTFRTEQAAACHVPEDAIRNIEFTATSEKLQVSFDVQHPVKQTAAEINKRLQEFPSRGMDRMLCDVDQPKKGLDRAIVEVCRAFDLREHAFRGMTFDKFIEEVAMKGRVGDKDAYESEIGDLLMLLDKIHNENRSLQYTLEKSAEEFRRQTASTMREQESLRQRNGELHAEIGRLRDLVEKLRDLADNQASELELLKLQKTQANQIRAQRNLSTFRGDDTAEPVYCVTLDELREQTEHCDQVERELERQREQCQNLLNAQDDLLAELSGVSEEKEKLEAECERLEAELRQMEEKSRLSEQGLSEMTQRLEEKQAEIEGLLENLEQLDEQLEALRAAEKSAQAHIEARDREISDLQQRLEGEIDDHIKTTALLEELRKHYNNLEELFDKQEAELMAYREKRQNAHKVRSLEPTLRPIGTQTKPFQEVVSADEISSEPLLSVTLDEYNDHMHRSNQFQQENDLLRQQLQQANDERENLHDRLEQLMAENQSLSEQLHNMHEELEREERDRSGVTLQNERLAEEIQRKTAENEQLVLENNKSRSDIRNLNVQVQRLMEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEALDLKAAENEKLAEELELKVAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEALDLKAAENEKLAEELDLKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKAAENEKLAEELELKVAENEKLAEELELKVAENEKLAEELELKVAENKRLAEEVTQRLSEKELLAEDTSARLLEADSANSALQCKVKHLEEKLTLLSSEKETALATLEAEIVDLLTQLKGLNGTNSALESLCASKEKELVFLREHCELWTDPTTKKEKVITRHVKVFDGNEWMKLITDRPEALMSAFVIDAGNACHVPGDQIHEVSFLNNKEKH
What is the function of this protein?
A component of FAZ filament that is required for correct FAZ assembly and attachment.  Not essential for new flagellum growth (By similarity).
What are the official names of this protein?
Flagellar attachment zone protein 1.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum.