PharMolix/UniProtQA huggingface dataset:
Protein: NDUS7_RECAM
Sequence: MEERCFRLGIKTNYKKEIFMILNNKQNKTEFIVSKMDELVNWARKGSLWPMTFGLACCAVEMMHSAASRYDLDRFGIIFRPSPRQSDVMIVAGTLTNKMAPALRKVYDQMSEPRWVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGLLQLQKKIKRSRKTLYWLQK
What are the official names of this protein?
NADH-ubiquinone oxidoreductase 20 kDa subunit, NADH dehydrogenase subunit 10.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CTNA1_BOVIN
Sequence: MTAVHTGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQCDLMKSAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKLVEDGILKLRNAGTEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQHPGAGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLVEAAKNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEFKAMDSI
What is the function of this protein?
Associates with the cytoplasmic domain of a variety of cadherins.  The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.  Can associate with both E- and N-cadherins.  Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions.  In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.  The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments.  Involved in the regulation of WWTR1/TAZ, YAP1 and TGFB1-dependent SMAD2 and SMAD3 nuclear accumulation (By similarity).  May play a crucial role in cell differentiation (By similarity).
What are the official names of this protein?
Catenin alpha-1.
What is the protein family that this protein belongs to?
Belongs to the vinculin/alpha-catenin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Note=Found only at cell- cell boundaries.
Protein: UXAB_YERPN
Sequence: MQTLNRRDFPGRSHPDKIIQFGEGNFLRAFVDWQIDLLNEHTDLNAGIVVIRPIDTDFPPSLSTQDGLYTAVIRGLNEQGEAVRESRLIRSVNREINIYRQFDDYLALARDANIRFMFSNTTEAGIAWNEADQFSDAPPSSFPAKLTRLLFERFEHFDGAADKGWVLLPCELIDYNGEALRELVLRYASHWQLPAAFTHWLTENNTFCSTLVDRIVTGYPRDEVAALQTELGYQDSFLDTAEYFYLFVIQGPQGLAQELRLDQLDLNVRIVDDIKPYKERKVAILNGAHTALVPVAYLSGLDTVGQTMDDAQISRFVEKTITEEIVPVLDLPEDELLSFSQAVLSRFRNPFIQHQLLSIALNGMTKFRTRILPQLLTYQQQKGQLPPRLTFALAALIAFYRGEREGQTYPLQDDAHWLERYSTLWNGVKHGDIALAELVNRVLSDANHWGQDLTAVPQLANQVTEQLQTILSRGMRAAVAAYS
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: ILVB_PARMW
Sequence: MTLTSASTVVGGLDANAPQTISGAAALMDALRRHGVDTIFGYPGGAILPIYDALHIAESEGWVKHILVRHEQAGTHAADAYARATGKVGVCFGTSGPGATNLVTGIATAQMDSVPMVVITGQVPRPAIGTDAFQETDIFGITLPIVKHSWVVRDPADLGSIVAQAFLIAASGRPGPVLIDIPKDVGQEQFNYVPVEPGSVIPGGFHQPEPPLDAAVAAALDLIEQAQRPLLYVGGGAISACAHDSLRMLAERYQLPVTTTLMGKGAFDENDALSVGMLGMHGTAYANFAVTECDLLIAVGARFDDRVTGKLDTFAPRARVVHFEIDPAEIGKNRKADVAVLGDLGLSLARMVEISLQRTAEPRTAAWLERINTWKDRYPLTIPPAEGAIYPQEVLLAVRDLAPDAIVTTDVGQHQMWAAQHLRNGPRGWISSAGLGTMGFGMPAAMGAQVAMPDRQVVCIAGDASILMNIQELGTLAAYGLPVKVVIVNNHWQGMVRQWQESFYDERYSASDMLNGMPDFIALARSFGVDGVKITDRELLHRDLAAALQSPTPTMIDVHVRRGENCYPMVPPGKSNAQMVGLPSHPELAMGTTRTCSSCGAITAHEHRFCPQCGASL
What are the official names of this protein?
Acetolactate synthase large subunit, AHAS, Acetohydroxy-acid synthase large subunit, ALS.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: MODE_YERPE
Sequence: MQAEILLTLKLQQRLFADPRRIALLKQIQHTGSISQGAKLAGISYKSAWDAINDMNTLSEEILVERATGGKGGGGAHLTRYGERLIQLYDLLATIQQKAFDTLKDDSLPLDSLLAAISRFSLQTSARNQFFGTLIERDHQQVQQHVNILLSDGKTRLTAAITQQSADRLQLSAGKEVLALIKAPWVKLVTDPALAGAADNALPGTVASIEPGNDHSEVIVTLTGGANLCSTQNNSELHALNLRVGSAVIAQFNADRVIIATLC
What is the function of this protein?
The ModE-Mo complex acts as a repressor of the modABC operon, involved in the transport of molybdate.  Upon binding molybdate, the conformation of the protein changes, promoting dimerization of ModE-Mo.  The protein dimer is then competent to bind a DNA region, upstream of the modABC operon.  Acts also as an enhancer of the expression of genes coding for molybdoenzymes, both directly and indirectly (By similarity).
What are the official names of this protein?
Transcriptional regulator ModE.
What is the protein family that this protein belongs to?
Belongs to the ModE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y013_ACTSZ
Sequence: MENQSLMPREKLLKSGAETLENYELLAIFLRTGIKNCPVIQLSQAVLRYFGSLRGLISADQEQFCQFKGIGITQYIQLQACTEMTKRYLAEELTFAHEFTNPLTVRLYLQTELEHYEREVFSVLFLDNQHRLIKKEDMFRGTINAASVYPREIIKTALYCNAAALILAHNHPSGSAEPSASDKQMTKRIQAAAELMEIRVLDHFVIGKGCYFSFAEQDWL
What are the official names of this protein?
UPF0758 protein Asuc_0013.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: FMT_YERPN
Sequence: MSDSLRIIFAGTPDFAARHLGALLSSQHKIVGVFTQPDRPAGRGNKLTPSPVKILAEHHGIPVFQPKSLRPEENQHLVADLNADIMVVVAYGLILPAAVLAMPRLGCINVHGSLLPRWRGAAPIQRSVWAGDEKTGITIMQMDIGLDTGAMLHKIECAIQPEDTSATLYDKLAQLGPQGLLITLQQLAAGTALAEVQNETQATYAEKLSKEEAKLDWTLSATQLERCIRAFNPWPVSYFIVDEQPIKVWQAQVLPAGEDAEPGTIIHADKHGIQVATADGVLNITQLQPAGKKAMSAADLLNSRREWFIPGSQLV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: ALKJ_PSEOL
Sequence: MYDYIIVGAGSAGCVLANRLSADPSKRVCLLEAGPRDTNPLIHMPLGIALLSNSKKLNWAFQTAPQQNLNGRSLFWPRGKTLGGSSSINAMVYIRGHEDDYHAWEQAAGRYWGWYRALELFKRLECNQRFDKSEHHGVDGELAVSDLKYINPLSKAFVQAGMEANINFNGDFNGEYQDGVGFYQVTQKNGQRWSSARAFLHGVLSRPNLDIITDAHASKILFEDRKAVGVSYIKKNMHHQVKTTSGGEVLLSLGAVGTPHLLMLSGVGAAAELKEHGVSLVHDLPEVGKNLQDHLDITLMCAANSREPIGVALSFIPRGVSGLFSYVFKREGFLTSNVAESGGFVKSSPDRDRPNLQFHFLPTYLKDHGRKIAGGYGYTLHICDLLPKSRGRIGLKSANPLQPPLIDPNYLSDHEDIKTMIAGIKIGRAILQAPSMAKHFKHEVVPGQAVKTDDEIIEDIRRRAETIYHPVGTCRMGKDPASVVDPCLKIRGLANIRVVDASIMPHLVAGNTNAPTIMIAENAAEIIMRNLDVEALEASAEFAREGAELELAMIAVCM
What is the function of this protein?
Converts aliphatic medium-chain-length alcohols into aldehydes.  May be linked to the electron transfer chain.
What are the official names of this protein?
Alcohol dehydrogenase [acceptor].
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: RECR_RICCN
Sequence: MNETNDNDIDQLIYLFSKLPGLGIRSARRIALYLLQDKDIRLKSLINNLVEIDKKIVKCEICGNMDTENMCRICSSEYRDKSIIAIVETVAELWAMERSGNFKGLYHVLGHNLSATSRQNPSILRLPELLTRCFAENIKEVIIATNSTLEGQTTAYFITEYLKEHPAKISRLASGIPIGGELDYLDEGTVSAAINLRQPFE
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: NAGB_THEPX
Sequence: MKVIITVNYEEMSKKAAEIVKKQIKEKPNTVLGLATGSTPLGMYKHLIEMYKRGEIDFSNVITFNLDEYIGLSPDHPQSYHYFMFHNFFNHINIKKENVHIPNGIAEDLEEECRKYEEEIEKAGGIDLQILGIGINGHIGFNEPDESIETKTHVVTLTEKTINANKRFFKSAEEVPRKAITMGLGSIMKAKKIVLLASGKNKAEAIKETIKGQLTTKVPATVLALHHDVTIIIDKEAASLIPDEDLKEIEVIV
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: NU2C2_POPTR
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDMPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMIVGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVLSIYYYLKIIKLLMTGQNQEITPHVRNYRGSPLRSNNSIELSMIVCVIASTIPGISMSPIIEIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MED31_DROME
Sequence: MAKMYGKGKTAIESEELQKRRWQIELEFVQCLSNPNYLNFLAQRGFFKDQSFINYLKYLQYWKEPDYAKYLMYPMCLYFLDLLQYEHFRREIVNSQCCKFIDDQAILQWQHYTRKRIKLIENVTAAQQQQQQLQQQQQQANGMEAATGGESAAPTPNVNGSASTADSQQTSSALQPVQAQPGNPQQQQQINGVASGANIKLELN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  Required for activated transcription of the MtnA gene.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31, Protein SOH1, dSOH1.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APF12_GIBF5
Sequence: MGIAQPGELAPVPRFRHLPFTIPNGIGRDTYLKIHNVMNHLGRAVLVGQHRRLIQALSSDLGVDSLVAMVSISMQDSEVCSAFSVYLTTLEQAYHWPRESTLSTPEQLEDHKLVIQMLQQPELRDTLVASVHAQYDHSATPAQVALSALSIAKQMIDQATETRSNKTKLPTEIQDLVNLLYRTSRGDWFIQGNYTDPDSHKEFGRLHEVIRTNGTQRSVQEIFQRFNGISWLQRMPLLHQNFASNSSILCAAYADLQVAMALARDELFSMVIDEPIWGLTFAKFSKGVGLCTIGAGGADCPMFRMMDALCGRADNINQAALLDELDFRSRFFPPGMRALINDLVTAPSVRSHISSGEASYELTQAFRAMEQIRYDLYEMHRKKAMRIALALRAGQQATSSGVQNATTPEKYIASTLSAAIKVRFGQEPARPQVDAFAWSTPLLCSDTGVIQTSRIQFVFSTPLAVSPGDSLRVAVEVEQGDWHIRTYSITHAYARQGSSKARDQICQAVGSAEICVRSKGQVSSFLCNQKTGFPVRVMIKPAPHFRIAGNTSPHEETLFVAQGGAVCVFLAWLAWQKQLVGTYRLVVGARNYNMLAYVGQLEKISSSFGSHLIVHVVLSRPGHGDIQRFVPGNIKASTGRVTHHLGLFSSCSTKATYVCGSASFALDVVRCLSQGPGTKREVPKVSRLQPIVTSRLPHFRLHVAAATENGTDKPCLNQITKLELALHNSPGDLWIALGDRVFDISQVPSFHPGGEKVLMYRAGRQAQDVFDTVHEGCYMISSLLNEMVIGRLDSARGEFSQWEDYLDKIVEIQNDLTNHSRIEQAPTGSIEQLAESPPVEILRGATNCFVKGWSSLLQQSGIGDSGVVSLLSSHQDAISALDAHVRMVYENDFEDPVRYANALRKIFDAHSRLVCGIHTAIDELKRHIVERLVEGDEPELTSLHISTARISQQLRETSKSY
What is the function of this protein?
Cytochrome b5-like reductase; part of the gene cluster that mediates the biosynthesis of the cyclic tetrapeptide apicidin F (APF) (PubMed:25058475).  The non-ribosomal peptide synthetase apf1 incorporates four different amino acids to produce apicidin F: L-phenylalanine, D-pipecolic acid (D-pip), N-methoxy-L-tryptophan and L-2-aminooctanedioic acid (PubMed:25058475).  L-Phenylalanine is the only proteinogenic amino acid directly used by apf1 (PubMed:23825955, PubMed:25058475).  The 3 other apf1 substrates are non-proteinogenic and have to be modified by other enzymes of the cluster (PubMed:25058475).  Lysine is converted to delta-1-pyrroline-5-carboxylate (P5C) which is reduced to L-pipecolic acid (L-pip) by apf3 (PubMed:25058475).  L-pip is epimerized to D-pip, probably by apf1 activity, prior to incorporation (PubMed:25058475).  L-Tryptophan is N-oxidyzed by one of the cytochrome P450 monooxygenases (apf7 or apf8), and further methylated at the hydroxy group by the O-methyltransferase apf6 to yield N-methoxy-L-tryptophan (PubMed:25058475).  The synthesis of the fourth apf1 substrate is more complex (PubMed:25058475).  The fatty acid synthase apf5 is involved in the synthesis of the octanoic acid backbone of L-2-aminooctanedioic acid by fixing one acetyl-CoA unit and three malonyl-CoA units (PubMed:25058475).  Then one of the cytochrome P450 monooxygenases (apf7 or apf8) may oxidize this backbone to 2-oxooctanoic acid (PubMed:25058475).  The aminotransferase apf4 is predicted to catalyze the exchange of the keto group with an amino group (PubMed:25058475).  The next step would be the oxidation of 2-aminooctanoic acid by one of the cytochrome P450 monooxygenases (apf7 or apf8).  The last step is the oxidation of 2-amino-8-hydroxyoctanoic acid to 2-aminooctanedioic acid is catalyzed by the FAD-dependent monooxygenase apf9 (PubMed:25058475).
What are the official names of this protein?
Cytochrome b5-like reductase apf12, Apicidin F synthesis protein 12.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: MIAA_RHIME
Sequence: MMQNLARDIDAILITGPTASGKSALAVKLAQRHGGVVINADSMQVYGTLKVLTARPDQSEMGGVEHFLYGHIPPGRAYSTGVWLREAEALVARLGKEGRLPVFVGGTGLYFKALTGGLSDMPEIPLETRKRLRTRLTEEGAEALHGELSARDPETAGRVRPSDGQRIVRALEIIEATGRPIGSYQQSRGPVIIDPARAQKIVVLPERPVLHGRIDRRFETMLARGAVEEVRALLALRLPPEMPVMKAIGVPQIAAMLKGEMSEKQVIEAGAAATRQYAKRQMTWFRNQLDETWQRIEDPDALG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RSMA_SHESM
Sequence: MSSKVHLGHTARKRFGQNFLTDDNVINRIVGAIAPDNDHVMVEIGPGLGALTEPVATAIDNLTVVELDRDLVERLQNHPVLKDKLTIHQGDALQFDFSQLVVPGKKLKVFGNLPYNISTPLMFHLFEFAEQIETMHFMLQKEVVLRLSASPGNKAYGRLTVMAQYFCQVVPVLEVPPHSFAPPPKVDSAVVRLLPYAEKPFPCKDVNVLRQLCTTAFNMRRKTLRNNLKQVLSDAEFEQLGIDPNLRPEQISVEQYVAMANMVCDKQA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HVM12_MOUSE
Sequence: EVQLQQSGPELVKPGASVKMSCKASGYTFTDYYMKWVKQSHGKSLEWIGDINPNNGGTSYNQKFKGKATLTVDKSSSTAYMQLNSLTSEDSAVYYCARDYDWYFDVWGAGTTVTVSS
What are the official names of this protein?
Ig heavy chain V region MOPC 104E.
Protein: STKLE_ARATH
Sequence: MSKKHLKPLETCFEDEEDDVIYLPPGLVTGATSKKNEEFCGGSGKVQPSEMKRRSEGTSTDMTSKRAKKVSAEDEKKVGEWTKNPYFQRLWSEEDEIVMLQGIIKFEDVTGKSPFEDRHGFIEFVKNSISFEASVQQYIGKISQLKRKYTRKRKNGFSEGHEQKCFKLAMSIWGTKETSKKTDLCSSPKGKKVKEEDGDVTNSDWFENSFLLPSIESLGVDSVKRKWNVVPMEFKKKIEERLELLEADESECKKMEEMLKVKNSECVKQKTNLLNEVIDVMT
What are the official names of this protein?
Probable transcription factor At1g66420, Storekeeper-like protein At1g66420.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
Protein: STK10_HUMAN
Sequence: MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEEIEDGRDEGEEEDAVDAASTLENHTQNSSEVSPPSLNADKPLEESPSTPLAPSQSQDSVNEPCSQPSGDRSLQTTSPPVVAPGNENGLAVPVPLRKSRPVSMDARIQVAQEKQVAEQGGDLSPAANRSQKASQSRPNSSALETLGGEKLANGSLEPPAQAAPGPSKRDSDCSSLCTSESMDYGTNLSTDLSLNKEMGSLSIKDPKLYKKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSNKHELQLEQMHKRFEQEINAKKKFFDTELENLERQQKQQVEKMEQDHAVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAEQREKIKQFSQQEEKRQKSERLQQQQKHENQMRDMLAQCESNMSELQQLQNEKCHLLVEHETQKLKALDESHNQNLKEWRDKLRPRKKALEEDLNQKKREQEMFFKLSEEAECPNPSTPSKAAKFFPYSSADAS
What is the function of this protein?
Serine/threonine-protein kinase involved in regulation of lymphocyte migration.  Phosphorylates MSN, and possibly PLK1.  Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN.  Acts as a negative regulator of MAP3K1/MEKK1.  May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.
What are the official names of this protein?
Serine/threonine-protein kinase 10, Lymphocyte-oriented kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: NUSB_ECO7I
Sequence: MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDVLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKVAINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NOD2_MOUSE
Sequence: MRSSCCDMCSQEEFQAQRSQLVALLISGSLEGFESILDWLLSWDVLSREDYEGLSLPGQPLSHSARRLLDTVWNKGVWGCQKLLEAVQEAQANSHTFELYGSWDTHSLHPTRDLQSHRPAIVRRLYNHVEAMLELAREGGFLSQYECEEIRLPIFTSSQRARRLLDLAAVKANGLAAFLLQHVRELPAPLPLPYEAAECQKFISKLRTMVLTQSRFLSTYDGSENLCLEDIYTENILELQTEVGTAGALQKSPAILGLEDLFDTHGHLNRDADTILVVGEAGSGKSTLLQRLHLLWATGRSFQEFLFIFPFSCRQLQCVAKPLSLRTLLFEHCCWPDVAQDDVFQFLLDHPDRVLLTFDGLDEFKFRFTDRERHCSPIDPTSVQTLLFNLLQGNLLKNACKVLTSRPDAVSALLRKFVRTELQLKGFSEEGIQLYLRKHHREPGVADRLIQLIQATSALHGLCHLPVFSWMVSRCHRELLLQNRGFPTTSTDMYLLILQHFLLHASPPDSSPLGLGPGLLQSRLSTLLHLGHLALRGLAMSCYVFSAQQLQAAQVDSDDISLGFLVRAQSSVPGSKAPLEFLHITFQCFFAAFYLAVSADTSVASLKHLFSCGRLGSSLLGRLLPNLCIQGSRVKKGSEAALLQKAEPHNLQITAAFLAGLLSQQHRDLLAACQVSERVLLQRQARARSCLAHSLREHFHSIPPAVPGETKSMHAMPGFIWLIRSLYEMQEEQLAQEAVRRLDIGHLKLTFCRVGPAECAALAFVLQHLQRPVALQLDYNSVGDVGVEQLRPCLGVCTALYLRDNNISDRGARTLVECALRCEQLQKLALFNNKLTDACACSMAKLLAHKQNFLSLRVGNNHITAAGAEVLAQGLKSNTSLKFLGFWGNSVGDKGTQALAEVVADHQNLKWLSLVGNNIGSMGAEALALMLEKNKSLEELCLEENHICDEGVYSLAEGLKRNSTLKFLKLSNNGITYRGAEALLQALSRNSAILEVWLRGNTFSLEEIQTLSSRDARLLL
What is the function of this protein?
Pattern recognition receptor (PRR) that detects bacterial peptidoglycan fragments and other danger signals and plays an important role in gastrointestinal immunity (PubMed:19805227, PubMed:21715553).  Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3, INAVA and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling.  This in turn leads to the transcriptional activation of hundreds of genes involved in immune response (PubMed:22607974).  Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed:18511561).  Component of an autophagy-mediated antibacterial pathway together with ATG16L1.  Also plays a role in sensing single-stranded RNA (ssRNA) from viruses.  Interacts with mitochondrial antiviral signaling/MAVS, leading to activation of interferon regulatory factor-3/IRF3 and expression of type I interferon.  Besides recognizing pathogens, participates in surveillance of cellular homeostasis through sensing and binding to the cytosolic metabolite sphingosine-1-phosphate and then initating inflammation process.
What are the official names of this protein?
Nucleotide-binding oligomerization domain-containing protein 2, Caspase recruitment domain-containing protein 15.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Basolateral cell membrane.
Protein: STEP1_ARATH
Sequence: MALSQVSASLAFSLPNSGALKLATITNPTSTCRVHVPQLAGIRSTFASGSPLLPLKLSMTRRGGNRAASVSIRSEQSTEGSSGLDIWLGRGAMVGFAVAITVEISTGKGLLENFGVASPLPTVALAVTALVGVLAAVFIFQSSSKN
What is the function of this protein?
May be involved in non-photochemical quenching, a process that maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage (By similarity).  May play a photoprotective role in the thylakoid membrane in response to light stress (Probable).
What are the official names of this protein?
Stress enhanced protein 1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ELIP/psbS family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.