PharMolix/UniProtQA huggingface dataset:
Protein: EIF3G_ASPCL
Sequence: MSRLGNRADWADDEEFDDPSALPPQQVTTNKDGTKTVVSYRFNDEGKKVKVTRRIKTTVVREHVNPQVAERRSWAKFGLEKGHAAGPSFDTTSVGENIVFRPSVNWRAQAAEAEKAGGEKGSIKDQLKDKKVKCRICSGEHFTARCPFKDTMAPVDESTGAAGGEPGAEDEAAAGGLGAGTSSYVPPHMRKGAASGGERMAGKYEKDDLATLRVTNVSELAEESEIRDLFERFGRVTRVFLARDRETQRAKGFAFISFADRSDAARACEKMDGFGYRHLILRVEFAKRAT
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Translation initiation factor eIF3 p33 subunit homolog, eIF3 p33 homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWC27_BOVIN
Sequence: MSNIYIQEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGDPTGTGTGGESIYGVPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLRLTEVDIDDEERPRNSHKIRSCEVLFNPFDDIIPREIKKPKKEKPEEEVKKLKPKGTKNFSLLSFGEEAEEEEEEVNRVSQSMKGKSKSSHDLLKDDPHLSSVPAVESERGDAAEDSDDDGEYEGAEHDEYVDGDEKNQMRERIAKKLKKDTSENVKRAGEGEVEKKPVSRSEELRKEARQLKRELLAAKQKKAENSAIQAEKRSEEEEAAPDGAVAEYRREKQKYEALRKQQAKTGTSREDQTLALLNQFKSKLTQAIAETPENDISETEVEDDEGWMSHVLQFEDKSRKVKDASMQDSDTFEIYDPRNPVNKRRREESKKLMREKKERR
What is the function of this protein?
As part of the spliceosome, plays a role in pre-mRNA splicing.  Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
What are the official names of this protein?
Spliceosome-associated protein CWC27 homolog, Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog, PPIase CWC27.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VPB41_MYCTU
Sequence: MKTTLDLPDELMRAIKVRAAQQGRKMKDVVTELLRSGLSQTHSGAPIPTPRRVQLPLVHCGGAATREQEMTPERVAAALLDQEAQWWSGHDDAAL
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Upon expression in M. smegmatis neutralizes the effect of cognate toxin VapC41.
What are the official names of this protein?
Antitoxin VapB41.
Protein: RS7_AERPE
Sequence: MSGQGTGFSLGEGVEVRPDKIRLFGKWSWVGVEVRDPSLKRYINLKPVWLPHTGGRHEKRRFGKAEVPIVERLMNKLMRPGRNGGKKHLAYNIVKTAFDIIYFETGENPIQVLVKAIENSAPREDTTKITYGGITYRVSVDVAPQRRVDQALKFIADGARQCAFNNPKPIEECLAEELILAARGDPRSYAIRQKEEIERIALSSR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PSBB_PINKO
Sequence: MGLPWYRVHTVVLNDPGRLISVHIMHTALVAGWAGSMTLYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGIKDSWSGWNITGETVINPGIWSYEGVAGAHIMFSGLMFLAAIWHWVYWDLEIFYDERTGKLCLDLPKVFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKIQPVDPAWGAEGFDPFVPGGIASHHIAAGILGILAGLFHLSVRPPQRLYVGLRMGNIETVLSSSIAAVFFAAFIVAGTMWYGSATTPVELFGPTRYQWDQGYFQQEIDRRVRAGLAENLSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGAMDNGDGIAVGWLGHPIFKDKEGNELFVRRMPTFFETFPVVLVDKEGIVKADVPFRRAESKYSVEQVGVTVEFYGGGLDRVSFGDPAIVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHATFALLFFSGHIWHGARTLFRDVFAGIDPDLDSRIEFGAFQKLGDPTTKRQVV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: APAH_SHEPC
Sequence: MAHYFVGDVQGCFTELQKVLEKVDFNPSQDELWAVGDLVARGPDSLATLRFFKSLGDSAKTVLGNHDLHLMAIHGKLKRDKPSDNLKALLKADDINELIDWLRQQPLMRELPEQQLIMTHAGVPPQWSLETLRQESALVSHALKQDDYLEALISQMYTDSAERWEPTALGIARLRFCINALTRMRYLYVDGHLNFDCKQPPQDCTDPQLRPWYEYTSPLRQSHTLVFGHWAALMGNVNDKKLKALDTGCCWGEHLTLWHLEKDQKITQKRLKKS
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: GPA8_CAEEL
Sequence: MGALCSSETYMLDKEEYKKQVEHNKSIENDLEKDRKIKILKLLILGPGESGKSTTIKQIKIIHDEGYSAEEKMVRKHGIYMNILEGIEEIHLSVGRENKSYKNPLSFDHINEVRMFTENFKKADDSEKLLGPEVINAIQKYIKDETIAMMLRDKTVYNIDDSTIYFLENFSRIIQKDYLPTEEDILKSRVPTSGVIQYKIMLKNFNFRIFDVGGQRAQRRKWLHVFDDVQAVLFITSLSEYDQVLREDATVNRMKESLNLFEKICNGRYFLNTAMILFLNKIDLFKIKIKHTNITVALTSYKGPQECDSALDYIRKRFISLNKNKKRSIYEHVTCATDTEQIQVVIDSVIDVVIQHTMQKVGIQ
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-8 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: PDRP2_LATSS
Sequence: MTAIPIFIISDSIGETARTVIAAVNAQFPASVTLKIQRFPFITDQKTLTPILQDAHQEQAIIVSTLVNHTLQETVTQFCQAKHLTLIDLLSPLTTAISERSQTASLETPGSLRKLDEHYFHRISAMEFAVRYDDGQDPRGLLEADIVLLGVSRTSKTPLSMYLANQNYRVANLPLIPNVPLPKELFKVPAHKIIGLTMPLSTLLKIRQERLATLGLPQTTNYSNMTTVGDELAYANQIFEQLNATTINVADRSIEETASLIQTLI
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 2, PPDK regulatory protein 2.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: PSAB_SOLLC
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFESWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSAISLIAGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGEYVRWNNFLDVLPHPQGLGPLFTGQWNLYAQNPDSSSHLFGTAEGAGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFIFLVAGHMYRTNFGIGHSMKDLLDAHIPPGGRLGRGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTTGPAFNAGRSIWLPGWLNAVNENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AIF1_MOUSE
Sequence: MSQSRDLQGGKAFGLLKAQQEERLEGINKQFLDDPKYSNDEDLPSKLEAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSGSEETFSYSDFLRMMLGKRSAILRMILMYEEKNKEHKRPTGPPAKKAISELP
What is the function of this protein?
Actin-binding protein that enhances membrane ruffling and RAC activation.  Enhances the actin-bundling activity of LCP1.  Binds calcium.  Plays a role in RAC signaling and in phagocytosis.  May play a role in macrophage activation and function.  Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.  Enhances lymphocyte migration.  Plays a role in vascular inflammation.
What are the official names of this protein?
Allograft inflammatory factor 1, AIF-1, Ionized calcium-binding adapter molecule 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, phagocytic cup. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Protein: FOLD_STAAM
Sequence: MVAKILDGKQIAKDYRQGLQDQVEALKEKGFTPKLSVILVGNDGASQSYVRSKKKAAEKIGMISEIVHLEETATEEEVLNELNRLNNDDSVSGILVQVPLPKQVSEQKILEAINPEKDVDGFHPINIGKLYIDEQTFVPCTPLGIMEILKHADIDLEAKNAVVIGRSHIVGQPVSKLLLQKNASVTILHSRSKDMASYLKDADVIVSAVGKPSLVTKDVVKEGAVIIDVGNTPDENGKLKGDVDYDAVKEIAGAITPVPGGVGPLTITMVLNNTLLAEKMRRGIDS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL6_CLOPE
Sequence: MSRVGKMPIAIPAGVTVTVTPENVVTVKGPKGELVKAMHKDINIAVEDAQVVVTRPSDVKEHRALHGLTRALLNNMVVGVSQGFSKTLELNGVGYRAQLQGKKLVMNLGYSHPVEVEAVDGVDFKLDGTTKVIVEGIDKEKVGAVAANIRSWRKPEPYKGKGIKYSDEVIRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HEMA_I67A2
Sequence: MKAILLVLLCTFAATNADTLCIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDRHNGKLCKLGGIAPLHLGKCNIAGWILGNPECELLFTVSSWSYIVETSNSDNGTCYPGDFINYEELREQLSSVSSFERFEIFPKTSSWPNHETNKGVTASCPYAGANSFYRNLIWLVKKGSSYPKLSESYVNNKGKEVLVLWGIHHPPTSTDQQSLYQNADAYVFVGSSKYNRKFKPEIAARPKVRGQAGRMNYYWTLIEPGDTITFEATGNLVVPRYAFAMNRGSGSGIIISDAPVHDCNTKCQTPKGAINTSLPFQNIHPVTIGECPKYVKSTKLRMATGLRNIPSIQSRGLFGAIAGFIEGGWTGMIDGWYGYHHQNGQGSGYAADQKSTQNAIDGITNKVNSVIEKMNMQFTAVGKEFNNLEKRIENLNKKVDDGFLDVWTYNAELLVLLENERTLDFHDSNVKNLYEKVRSQLRNNAKEIGNGCFEFYHKCDDTCMESVKNGTYDYPKYSEESKLNREEIDGVKLESTRVYQILAIYSTVASSLVLLVSLGAISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: MCA_STRCO
Sequence: MTDQLRLMAVHAHPDDESSKGAATMAKYVSEGVDVLVVTCTGGERGSILNPKLQGDAYIEENIHEVRRKEMDEAREILGVGQEWLGFVDSGLPEGDPLPPLPEGCFALEDVDKAAGELVRKIRSFRPQVITTYDENGGYPHPDHIMTHKITMVAFEGAADTEKYPESEYGTAYQPLKVYYNQGFNRPRTEALHHALLDRGLESPYEDWLKRWSEFERKERTLTTHVPCADFFEIRDKALIAHATQIDPEGGWFRVPMEIQKEVWPTEEYELAKSLVETSLPEDDLFAGIRDNA
What is the function of this protein?
A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor.  Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
What are the official names of this protein?
Mycothiol S-conjugate amidase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family. Mca subfamily.
Protein: L2CC_DROME
Sequence: MAAQFFNRIGQMGLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQSTLLNLPSTIAQ
What is the function of this protein?
Required for larval metabolism or for the progression of the larva into a pupa.
What are the official names of this protein?
Protein l(2)37Cc.
What is the protein family that this protein belongs to?
Belongs to the prohibitin family.
Protein: DCD_CHLMU
Sequence: MGIKEDNWIRKMAIEEGMIEPFADNQVKVHPETGEKLISYGLSSYGYDLRISREFKVFTNIYNSLVDPKCFTEDALISIVDDVCIIPPNSFALARSVEYFRIPRNVLTVCIGKSTYARCGLIVNVTPFEPEWEGYVTIEISNTTPLPAKIYANEGIAQVLFFEGDSACDVSYADRQGKYQKQQGITVPFV
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: WRK62_ORYSI
Sequence: MDDDGDGSSSPTDDSAAAGLLPLFSRSPAEDLEEKLRRAMEENARLTRALDAILAGHHAHQRALLAPSLSPPPPSATARAPSVSTSCAAREDAAPAVAAAAASTACPSRQQPPTAEPRPKVRTVRVRADAADATDANSMAETVKDGYQWRKYGQKVTRDNPYPRAYFRCAFAPSCPVKKKLQRCAEDRSMLVATYEGEHNHALSTQTTEFVASGCTTSQHAGGSSSSPLPCSISINSSGRTITLDLTNQAGSGSIASCGVEAAAVSGELVTVLSPELRRHLVEEVVQVLKNDAEFVEAVTNAVAARVVDQIPHIPVHL
What is the function of this protein?
Transcription repressor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.  Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity).  Regulates negatively basal innate immunity and XA21-mediated defense against X. oryzae pv.  oryzae (Xoo) (By similarity).
What are the official names of this protein?
WRKY transcription factor WRKY62, OsWRKY62, XA21-binding protein 10.
What is the protein family that this protein belongs to?
Belongs to the WRKY group II-a family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMA_PROMH
Sequence: MSDNSQKKVIVGMSGGVDSSVSAYLLKEQGYQVVGLFMKNWEEDDDTEYCSASADLADAQAVCDKLGIELHTINFAAEYWDNVFEHFLSEYKAGRTPNPDILCNKEIKFKAFLEYAAEDLGADYIATGHYVRRRDIDGKSQLLRGVDNNKDQSYFLYTLSHQQIAQSLFPVGEMEKPEVRKIAEKLDLATAKKKDSTGICFIGERKFTDFLSRYLPAKPGPIVTVDGETIGEHQGLMYHTLGQRKGLGIGGTKEGSEDPWYVVDKDVANNILIVAQGHEHPRLMSVGLIAQQLHWVAREPITEAFRCTVKTRYRQADIPCTVTPLDEDKIEVRFDYPVAAVTPGQSAVFYQDEVCLGGGIIETRIQE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_BACC4
Sequence: MYQSLMTVRETQIAIKEVKTFFEDQLAKRLELFRVSAPLFVTKKSGLNDHLNGVERPIEFDMLHSGEELEIVHSLAKWKRFALHEYGYEAGEGLYTNMNAIRRDEELDATHSIYVDQWDWEKIVQKEWRTVEYLQKTVQTIYGIFKDLEDHLFEKYPFLGKYLPEEIVFVTSQELEDKYPELTPKDREHAIAKEHGAVFIIGIGDALRSGEKHDGRAADYDDWKLNGDILFWHPVLQSSFELSSMGIRVDSKSLDEQLTKTGEDFKREYDFHKGILEDVLPLTIGGGIGQSRMCMYFLRKAHIGEVQSSVWPDDLREACKKENIHLF
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPB1_PREIN
Sequence: TDMLAVSVSSTDAIGHKYGT
What is the function of this protein?
Acts against tyrosine-phosphatases.
What are the official names of this protein?
Alkaline phosphatase, ALPase, PiALP.
Protein: PUR2_METBF
Sequence: MKILLIGGGGREHAIAEGIKKSKHNPSLYALMAKKNPGIAALCEDFLLEKETEVEKVVEYAKARNIEMAFVGPEAPLAAGVADALWEAGIPVVGPKKSCAIIEFDKAWARNFMKKYGIEGCPEYEVFTEEKPAHDFIEKLGDVAVKPSGLTGGKGVKVMGDQLPDLKAAKAYTSELLEKGSVVIEERFIGEEFTLQAFVDGKSLVFFPAVQDHKRAYEGDLGPNTGGMGSYTDAGEILPFMLPEDLEKAKKIMQDTVKALSEETGIGYQGILYGQFILTASGPKVVEFNARFGDPEAMNVISLLETDFVDIMSAVVKGTLGNLPVSFSKKATVCKYAVPAGYPENPEKDSEVTVEDIGDASIYYASVYEKEGKVYTTSSRAIAVIGIAETIAAAEKIAQNALENLHGKLFFRKDIGTAALIQKRIDHMKELRG
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: HIS2_CAUSK
Sequence: MSKLFEVLERLAATIETRKGGDPTSSYTAKLLNDPALAAKKLGEEAVETVIAAVAQGPDALASESADLLYHWLVLVAASDVSLDAVADKLAAREGTSGLAEKAARPS
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B561O_ARATH
Sequence: MDSSYLRISLSFLFWALLLSPAVSQSSSCSSQTFSGVKSYPHCLDLPDLKAILHYSYDASNTTLAVVFSAPPSKPGGWIAWAINPKSTGMAGSQALVASKDPSTGVASVTTLNIVSYSSLVPSKLSFDVWDVKAEEAANDGGALRIFAKVKVPADLAASGKVNQVWQVGPGVSNGRIQAHDFSGPNLNSVGSLDLTGTTPGVPVSGGGGAGNSRIHKRNIHGILNAVSWGLLFPIGAMIARYMRIFESADPAWFYLHVSCQFSAYVIGVAGWATGLKLGSESKGIQYNTHRNIGICLFSIATLQMFAMLLRPRKDHKFRFVWNIYHHGVGYSILILGIINVFKGLSILNPKHTYKTAYIAVIGTLGGITLLLEVVTWVIVLKRKSAKSTKPLKA
What is the function of this protein?
May act as a catecholamine-responsive trans-membrane electron transporter.
What are the official names of this protein?
Cytochrome b561 and DOMON domain-containing protein At4g12980, Protein b561A.tha15.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CD8B_RAT
Sequence: MQPWLWLVFSVKLSALWGSSALLQTPSSLLVQTNQTAKMSCEAKTFPKGTTIYWLRELQDSNKNKHFEFLASRTSTKGIKYGERVKKNMTLSFNSTLPFLKIMDVKPEDSGFYFCAMVGSPMVVFGTGTKLTVVDVLPTTAPTKKTTLKKKQCPTPHPKTQKGLTCGLITLSLLVACILVLLVSLSVAIHFHCMRRRARIHFMKQFHK
What is the function of this protein?
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses.  In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex.  The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins.  Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs).  In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.  A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.  Once LCK recruited, it initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of cytotoxic T-lymphocytes (CTLs).  Additionally, plays a critical role in thymic selection of CD8+ T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD8 beta chain, CD8 antigen 37 kDa chain, OX-8 membrane antigen.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Requires the partner CD8A for efficient cell surface expression. The heterodimer CD8A/CD8B localizes to lipid rafts due to CD8B cytoplasmic tail palmitoylation.
Protein: UXAC_PECCP
Sequence: MPQFLSEDFLLDSEFARRLYHEYAVDQPIFDYHCHLPPEQIAENYRFKNLYDIWLKGDHYKWRAMRTNGVPERLCTGDASDWEKFEAWAATVPHTIGNPLYHWTHLELRRPFGVTGTLLSPSTAKDIWDRCNAMLERDDFTARGIMQQMNVKMVGTTDDPIDDLRHHKTVAQDSSFSIKVLPSWRPDKAFNIELATFNDYMAKLGEVSDTDIRRFSDLQAALTKRLDHFAAHGCKVSDHALDVVMFAEADDATLDSILARRLSGETLSEHEVAQFKTGVLVWLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPLAQELSRLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMQRQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEDGEAPADLPLLGEMVKNISFDNAKNYFAIEL
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: DTD_YARLI
Sequence: MRAVIQRAKSGSVTVDSKIVSQISHGLVVLIGVGHEDTAEDVEKVANKIIKTKLWPSVDGAQQWKQSVLDVGGEVLCVSQFTLFAKVKKGQKPDFHNAAKGPQAKELYDQVLAKIQAALPEGRTVKDGVFGAMMDVALVNDGPVTIQYDTKNDK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_PSYA2
Sequence: MAENTVNAINVDPSEVEKFNKLAGEWWNKTGAFATLHEINPLRLNWIEENVKCGYVSADHQKTAEMGLAGKKVLDVGCGGGILSEAMARRGADVTGIDLGTENLKAASLHAEQSNLQDTLRYQHIPVEALAATHAGQFDVVTCMEMLEHVPDPAAIVDACFKLLAPGGVCVLSTINRNPKSYLFAIVGAEYVLRLLDRGTHDYAKFITPAELDKMAIDAGFTRQDIIGLHYNPLTKRYWLAQNVDVNYMMAVQKPRA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.