PharMolix/UniProtQA huggingface dataset:
Protein: RPN8_ASHGO
Sequence: MSVNYEQVNVAPLVLLSVLDHYKRMNTPDNKRCVGVLLGDNSGSTIKVTNSFALPFEEDEKNPDVWFLDHNYIENMNDMCKKINAKEKMIGWYHSGPKLRSSDLKINGLFKKYTQGNSLLLIVDVKQQGVGLPTDAYMAIEEVKDDGSSTERTFVHLPTAIEAEEAEEIGVEHLLRDVRDQAAGNLSLRLTNQLKSLQGLQRKLRDIVAYLDKVNSGQLPANHIILGKLQDVFNLLPNLGSPDEEAPATKKDDVLASSNTLQKALTVKTNDELMVIYISNLMRAIIAFDNLIENKIKNKKLQEAKRDPEPEEATKEEIQQQESAKA
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome regulatory subunit RPN8.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family.
Protein: MIIP_MOUSE
Sequence: MPNMAETKDPVRLRLLSLELLKQLWAGHEAMCRSVVRAASGSNLDCSSNNLEMPLSQETSSASSVAPSSQDKRHMLDPLDSRRDDTFDVAWYVKFNSRMDSFLPATGQHQEPQEELRPPSVPLLATQGLKGPVSLGGPKGLGPDKTQVPRSILSRLSKPSKPRVTSQESAVPESSWHSRPYLGYDWIAGSLDNSSPVTSEPEAFFSMLQRFRENNKEDCVCNSPEAVFPGLQESSGVEEDHECMYCYRINRRLFPEPVDPGAPCRLCGIPRDEKGPGTLVEPVQVRVSIPLSIMDPPHQYRIHRRKSFDASDTLALPRHCLLGWDILPPKSEKTSVPKSLDLWSSVSYGAGQRRDLSATSPPCQALPAQVTPPLWSEPQVAQLCPSH
What is the function of this protein?
Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1.  Exhibits opposing effects to IGFBP2 on cell invasion (By similarity).
What are the official names of this protein?
Migration and invasion-inhibitory protein, Invasion-inhibitory protein 45, IIp45.
Protein: RPC3_BOTFB
Sequence: MSKSKHAVELCSLLVDDIYGELSSLGLTVLVRQNLVYHNSEGSDTHYEANIDAAYALVRSGKILEIAEERFGSVAAEIMGQLVLLGHAKISDIIAELNKNHEPHANGNSNETNGATNGNGVHSYPSGQLNHTLIQLLEEGFIQPVGQNMFRSPTDSYNAVEKALLQDSYGGATRGTKQKDELRMRIRGQLQELRAQVPNWKPVGYNRSSTNGHTNDIASKRRRLSHSGGATNGYDFGDDESSKLDGNLVLRINHEKCTVFMRNRRLVELANSRIGVTTSYIYAELLRLMAEQIPRCRPDPRIDDAVDDADGPSIIITTQELTDALSKTINVSTGIGKATSQKIDTSRLDKLQNGRKRKAQDEAEVEGVASSDEESEDDHKPFTNGNGHAMDVDEDDPFSDQPGANTSKRAVTFKDRDRTPPPTESRQARMMHVMSHLQLLAADDCQLLRKCGARQMGEWTVDFERVIDRLRESELDSIIYENFGQIGHRLVRVMRKMGKLEEKHIAKLALIKQQDSRTTLVNMQMHGMVDIQEVPRDTGRMIVRTIHLWFCDEDRVTSLLLDRTYKAMSRCLQRLDVEKRRKANIIALSERTDVQGQEEAFLRPEQMNQLREIRAKEEDLLGQICRLDELVGIFQDY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit rpc3, RNA polymerase III subunit C3.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MENT_HUMAN
Sequence: MVPAAGALLWVLLLNLGPRAAGAQGLTQTPTEMQRVSLRFGGPMTRSYRSTARTGLPRKTRIILEDENDAMADADRLAGPAAAELLAATVSTGFSRSSAINEEDGSSEEGVVINAGKDSTSRELPSATPNTAGSSSTRFIANSQEPEIRLTSSLPRSPGRSTEDLPGSQATLSQWSTPGSTPSRWPSPSPTAMPSPEDLRLVLMPWGPWHCHCKSGTMSRSRSGKLHGLSGRLRVGALSQLRTEHKPCTYQQCPCNRLREECPLDTSLCTDTNCASQSTTSTRTTTTPFPTIHLRSSPSLPPASPCPALAFWKRVRIGLEDIWNSLSSVFTEMQPIDRNQR
What is the function of this protein?
Involved in control of cellular proliferation.  Onconcogenic modifier contributing to the tumor suppressor function of DNMT3B.
What are the official names of this protein?
Protein MENT, Methylated in normal thymocytes protein.
What are the subcellular locations of this protein?
Secreted.
Protein: COXX_SYNS9
Sequence: MAEVTATVALTRADVVPSRKRVKLPAWLEVAKPRLIPLLLATTLGGMALTEGWPLSSPRLICTLGGGALASAAAGVLNCLWEQDLDGRMNRTSGRALPSGRLSPTTAFIGAIACTLVAAMLLVSGVNCLAAGLSLLGLCSYVLLYTALLKPRTTQNIVVGGVAGAIPPLVGAAAATGHIGLGGWWLFALVMVWTPAHFWALALLLREDYRAVGIPMLPVVKGPVVTARAISRYGWATVLLSGFGILALPTGGLFYGLMLLPYNNRLLQLVHRLAADPDSLTNAKSLFRWSILYLFGICLLLILSRSALAAHLDQQMIAMLMQLSVA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CNPY4_BOVIN
Sequence: MGPVRLGTLLFILTVYGAWAGTPKEEEDDTERLPSKCEVCKLLSLELQEELSRTGRSREVLELGQVLDTGKRKRHIPYSVSETRLEEALENLCERILDYSVHAERKGSLRYAKGQSQTMATLKGLVQKGVKVDLGIPLELWDEPSVEVTFLKKQCETMLEQFEDVVGDWYFHHQEQPLQHFLCEGHVLPASETACLQETWTGKEKITDGQEKTEEEEQDQEEEEMTNTPVHSQHDPEDL
What is the function of this protein?
Plays a role in the regulation of the cell surface expression of TLR4.
What are the official names of this protein?
Protein canopy homolog 4.
What is the protein family that this protein belongs to?
Belongs to the canopy family.
What are the subcellular locations of this protein?
Secreted.
Protein: RFHPS_ARCFU
Sequence: MLRLRTPSRIHITLIDLNGSIGRVDGGVGLALEEPHIEIKAKESETFVLKGEPINRERFEIAAAKMAEYCGRGAEIEVVSDYDAHVGLGSGTQISLAVGRAFSELYGLNLTTRQIAEIMGRGGTSGIGVAVFDHGGLVVDGGHSTKEKKSFLPSSASRAKPAPMIARLDFPDWNVVLAIPDLKGFFGEREVNLFQKSCPVPLEDVREICHLILMKMLPAVVEADLDEFGKALKRIQELGFKKAEVEQYGELIKGCFDLADCIGMSSTGPTVYAITDSNAGGIERSLRDYFAEKGYECRTIVTKARNRGVEIEV
What is the function of this protein?
Catalyzes the condensation of 4-hydroxybenzoate (HB) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylphenol 5'-phosphate (beta-RFH-P) (By similarity).  Also catalyzes the condensation of 4-aminobenzoate (pABA) with PRPP to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) (PubMed:12142414).
What are the official names of this protein?
Beta-ribofuranosylphenol 5'-phosphate synthase, Beta-ribofuranosylaminobenzene 5'-phosphate synthase, Beta-RFA-P synthase, Beta-ribofuranosylhydroxybenzene 5'-phosphate synthase, Beta-RFH-P synthase.
What is the protein family that this protein belongs to?
Belongs to the beta-RFA-P synthase family.
Protein: EX7S_BURCM
Sequence: MAKTASPGATPPDNGTEPLPDNYEMALAELETLVARMEGGALSLEDSLAAYRRGANLVAFCQQQLEKVEQQVRVLDGATLKPLSSGTAATDGEDDDL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADEC_CLOBL
Sequence: MFNKFNTKPLWEVSKTLSSVAQGFEPADMVIINSRLINVCTREVIENTDVAVSCGRIALVGDAKHCIGENTEVIDAKGQYIAPGFLDGHIHVESSMLSVSEYARSVVPHGTVGIYMDPHEICNVLGLNGVRYMIEDGKGTPLKNMVTTPSCVPAVPGFEDTGAAVGPEDVRETMKWDEIVGLGEMMNFPGILYSTDHAHGVVGETLKASKTVTGHYSLPETGKGLNGYIASGVRCCHESTRAEDALAKMRLGMYAMFREGSAWHDLKEVSKAITENKVDSRFAVLISDDTHPHTLLKDGHLDHIIKRAIEEGIEPLTAIQMVTINCAQCFQMDHELGSITPGKCADIVFIEDLKDVKITKVIIDGNLVAKGGLLTTSIAKYDYPEDAMNSMHIKNKITPDSFNIMAPNKEKITARVIEIIPERVGTYERHIELKVKDDKVQCDPNKDVLKAVVFERHHETGKAGYGFVKGFGIKRGAMAATVAHDAHNLLVIGTNDEDMALAANTLIECGGGMVAVQDGKVLGLVPLPIAGLMSNKPLEEMAEMVEKLDSAWKEIGCDIVSPFMTMALIPLACLPELRLTNRGLVDCNKFEFVSLFVEE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: SYS_CLOB1
Sequence: MLDLKRIRNNSNEIKESLNNRGEKFDVTVIDEVLKLDEERRNILVKVEVLKSKRNQVSSEVPKLKKEGKDVSNIVAEMKNLSEEIKGFDTTLAKIDEKIQYIMLRIPNIPNPQVPDGDTDEDNIEIRNWSEPTKFDFEPKAHWDIGSNLNILDFERAGKVTGSRFTFYKGLGARLERSLISYFLDTHTEKHGYTEILPPYMVNRTSMIGTGQLPKFEEDAFKISEDDYFLIPTAEVPVTNLYRDEILKGDELPLKHVAYSACFRSEAGSAGRDTRGLVRQHQFNKVELVKFTKPEQSYEELEKLTNDAETVLKELGIPYRVVRICKGDLGFTAALKYDLEVWMPSYNRYVEISSCSNFEDFQARRANIRYKEDAKAKPQYVHTLNGSGVAIGRTVAAILENYQNEDGSVTIPEVLRPYMGGKEAIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_ECO27
Sequence: MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNVEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: APEA_THENE
Sequence: MKMERKNVWQHRNREEIESFSKEYMDFMGRAKTERLAVREIRKFLEKEGFVPIEDFAGDPMDMAVYAVNRGKAIAAFRVVDDLKKGLNLVVAHIDSPRLDFKPNPLVEDEQIALFKTHYYGGIKKYHWFNIPLEIHGVLFRGDGEEIEIHVGDKPEDPVFTIPDLLPHLDKEDAKISEKFKGENLMLIAGTIPLSGEEKEAVKMNVLKILNEMYGISEEDFVSGEIEVVPAFPPREVGIDRSLIGAYGQDDRICAYTALRAFLEANPKKSIGVVFLDKEEIGSDGNTGAKARFYLRVLRQILKIQGGPEIQNSHSMRYWKKSAVISGDVCAAVNPPYKDVHDLHNAPRSGYGVALVKYTGARGKYSTNDAHAEFVARVRQVLNERNVIWQVATLGKVDQGGGGTYAKFFAERGADVYDMGPALLGMHSPFEISSKADLFETYRAYRALLEDL
What are the official names of this protein?
Probable M18 family aminopeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
Protein: MSMO1_DANRE
Sequence: MEVNGTANILSSAFLAVEFVDSFLPQNPLQEPFKHAWNHMLQNYTKFQIATWGSLIVHELIYFLFCLPGFIFQFLPFMQKYKIQPDKPETWEKQWKCFKMLLFNHFCIQLPLICGTYYFTEFFSIPYDWDTMPRWPFLLAQCFGCAVIEDTWHYFLHRALHHRRIYKYIHKVHHDFTSPFGMQAEYAHPLETLILGAGFFIGTMVFCNHMILLWAWVTFRLLETIDVHSGYDIPLNPLHLIPFYAGARFHDFHHMNFVGNYGSTFTWWDRLFDTDSQFNKHYSHHKTAKSD
What is the function of this protein?
Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol.
What are the official names of this protein?
Methylsterol monooxygenase 1, C-4 methylsterol oxidase.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FB345_ARATH
Sequence: MDFVNNLDTDTSLSILSCLDDPSDIVRASAVSRSWRQFVVKYSLSKNLCLKLFHQLSNVDHIIETSNDRNGESSEAGSSSLMDTRLLEKEHRAFALLARGCMSSPIESCIADAIRASSTDNYPVESILNTLEKRDRIGRTPSYWSSTGQHKTTVPESLLYKLIGDLCLITEVSIHPFQAYFQRGHPIYSSHYVRFRLGHEKDNSPHYNNSQDKKGEPGKSSIESNYVWTYTSQEFSMAQENRLQSFQLPEPVLCIGGYLLVEFLGRVQTQEMDGQYYICVSHVKVEGRSLAKSFRVENVDDNGKFGLKVLSYNDPKKMEEMDAEAGQDMDAEAGQSQLRNLEQLLNLLHRHPLDVVDYVWPDESDDEYAESEDEAEP
What are the official names of this protein?
F-box protein At4g00755.
Protein: WECG_ECOBW
Sequence: MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAINAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMARAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASGAQIVTVAMGSPKQEIIMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWLYRLLSQPSRIKRQLRLLRYLRWHYTGNL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: DAPB_AKKM8
Sequence: MISILVTGISGRMGQAIQEAVTQNPDTCVGSTHDQGQELYPALAKCDVAIDFSHHAFTSTLLAEAVANNKPLVIGTTGHTELERQEIVDAAASIPIVFASNYSVGVNALFWLTRKAAQILGGSCDIEVMEMHHRHKIDAPSGTARTLAEILSGAIDRNYEDSVVFGREGLVGPRPAKEIGMHSLRGGDVVGDHTVIFASDGERLELTHKASSRMTFASGAVRAALWLQGREPGLYTMEDVLGLSQL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_ARCFU
Sequence: MKLVTCGLPYANGKAHVGHLRTYVPADVYVRYLRMSGEEVVFVCGSDCHGTPIVVNAEQQGLSPKELVDIYHEHFIKIFDALNIKFDFYGRTDSDYHHHRTTEIVKRLIEKGYVYPKEIQLAYCPKCQRFLPDRYVEGICPYCGALARGDECDQGCGRHLEPGEIKEPRCKICGSKAEFRSQRHYFFKLTEFQDFLEDYLSKLKGTENALNYARNWVKNLRDWCITRNLEWGVRFPGEPNLVVYVWVDAPIGYISFTEKACEEKGCDWRKIWIDGDAEIIHFIGLDIVYHHCIFWPAMLKGADYALPSAVVASGMVKVEGKTFSKSRGYVVWVEEDYLKSGLSPDYLRYYIVNYTSHQKDLNFSWEVFREKVNNEVIATLGNFLYRVLLFAWKNFGEVRMEGVDEEVLEKIRETEQKILSALEEWEFKAASDAFMELATYGNVYFQNAKPWELIKTDKEAARRAVASCLQLAKALIIFAYPVMPESMERMAKAIGLDLENVRLSDAYKVDEVMKLSKPEVPFAKVEDEVIEKLQKVMEKRFRGEGEKMEQKEEISIEDFQKLDIRIGRVLKAEKVKKSKKLIKLIIDIGDEQRQIVSGIAEDYTPEELEGKLVVVLANLKPAKFMGVESRGMILAAEKDGKAVLLTPEKEVEPGTRVC
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPSB_STAAN
Sequence: MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENHKLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: L_PUUMS
Sequence: MEKYRDIHERVKEAVPGETSAVECLDLLDRLYAVRHDVVDQMIKHDWSDNKDREQPIGLVLLMAGVPNDVIQSMEKRVIPGSPSGQILRSFFKMTPDNYKITGNLIEFIEVTVTADVARGVREKILKYQGGLEFIEQLLQIEAQKGNCQSGFKIKFNVVAVRTDGSNISTQWPSRRNEGVVQAMRLIQADINFVREHLIKNDERGALEAMFNLKFHVTGPKVRTFDIPNYRPQPLCQPILENLVDYCKNWLGTDHAFAFKEVTGQRVFNVFREEEEIHASKYGHSRKPRNFLLCQISLQSPYLPSTIASDQYDTRLACSEILKNYPETPLQLLARDMAYKYITLDHDDIINYYNPRVYFKPTQNIKEPGTFKLNLSNMDPKSKALIDVISKDSKKGVFGELIDSVDVASQVQHNECSKTIEKILSDLEVNLGDVANGLDQPKKTTGVDDILRKFYDNELVKYLISVIRKTTAWHLGHLLRDITESLIAHAGLKRSKYWSAHGYACGSVLLCILPSKSLEVAGSFIRFFTVFKEGLGLIDTDNLDSKAEIDGVSWCFSKIISLDLNRLLALNIAFEKSLLATATWFQYYTEDQGHFPLQHALRSVFAFHFLLSVSQKMKLCAIFDNLRYLIPAVTSTYSGFEPLIRKFFERPFKSALEVYLYGIIKVLLVSLAQNNKIRFYSRVRLLGLTVDQSTIGASGVYPSLMSRVVYKHYRSLISEATTCFFLFEKGLHGNLTEEAKIHLETVEWARKFREKERELGSYIMEEGYHIQDVLNNQVAVEQQLFCQEVVELAAQELNTYLHAKSQVMASNIMNKHWDKPYFSQTRNISLKGMSGALQEDGHLAASVTLIEAIRFLNHSQNNPTVLELYEQTKKQRAQARIVRKYQRTEADRGFFITTLPTRVRLEIIEDYYDAIAKVVPEEYISYGGERKILNIQQALEKALRWASGESEIQSSLGHSIKLKRKLMYVSADATKWSPGDNSAKFRRFTQSLYDGLRDDKLKNCVVDALRNIYETDFFISRKLHRYIDNMGELSDEVLDFLSFFPNKVSASIKGNWLQGNLNKCSSLFGAAISLLFKRVWAKLYPELECFFEFAHHSDDALFIYGYLEPIDDGTEWFQYVTQQIQAGNFHWHAVNQEMWKSMFNLHEHILLMGSIKISPKKTTVSPTNAEFLSTFFEGCAVSIPFIKILLGSLSDLPGLGYFDDLAAAQSRCVKALDMGACPQLAQLGIVLCTSKVERLYGTAPGMVNNPTAYLKVDRNLIPIPLGGDGSMSIMELATAGIGMADKNILKNAFITYKHAKKDNDRYVLGLFKFLMSLSDDIFQHDRLGEFSFVGKVQWKVFTPKSEFEFYDQYSRKYLELWSEQHPVYDYIIPRGRDNLLVYLVRKLNDPSIVTAMTMQSPLQLRFRMQAKQHMKVCKLGGEWVTFREVLAAADAFASEYRPTLQDMELFQTLVNCTFSKEYAWRDFLNEVQCDVLTTRQIHRPKVARTFTVKERDQTIQNPITAVIGYKYASKVDEISDVLDSALHPDSLSTDLQLMREGVYRELGLDISQPNVLKKVAPLLYKSGKSRIVIVQGNVEGTAESICSYWLKTMSLVKTIKVKPKKEVLKAVSLYGKKEKVGDLTHLAAMRLCIEVWRWCKANEQDSVTWLKYLVFENKTLEQWVDLFCSRGVLPIDPEIQCLGLLVYDLKGQKGLLQIQANRRAYSGKQYDAYCVQTYNEETKLYEGDLRVTFNFGIDCARLEIFWDKKEYILETSITQRNVLKILMEEVTKELLRCGMRFKTEQVNSSRSVVLFKTESGFEWGKPNVPCIVYRNCTLRTGLRVRHPTNKAFSITIQANGFRAMAQLDEENPRFLLAHAYHNLKDVRYQALQAVGNVWFKMTQHKLFINPIISAGLLENFMKGLPAAIPPAAYSLIMNKAKISVDLFMFNELLALINPQNVLNLDGIEETSEGFTTVSTISSTQWSEEVSLTLDDSDDDDDASNLDYTIDLDDIDFETIDLKEDIEHFLQDESAYTGDLLIQTEETEVRKLRGMIKILEPVKLIKSWVSKGLSIDKIYNPVNIILMTRYMSKHYNFQAKQLSLMDPYDLTEFESVVKGWGECVKDRFIELDQEAQRKVTEERVLPEDVLPDSFFSFRHADILLKRLFPRDSASSFY
What is the function of this protein?
RNA-dependent RNA polymerase, which is responsible for the replication and transcription of the viral RNA genome using antigenomic RNA as an intermediate (By similarity).  During transcription, synthesizes subgenomic RNAs and assures their capping by a cap-snatching mechanism, which involves the endonuclease activity cleaving the host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral transcription.  Cleaves ssRNA substrates but not DNA (By similarity).  Seems to downregulate the expression of its own and heterologous mRNAs through its endonuclease activity (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, RdRp, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the Bunyavirales RNA polymerase family.
What are the subcellular locations of this protein?
Host cytoplasm, host perinuclear region.
Protein: MENE_BACAN
Sequence: METMPNWLKQRAFLTPDRTAIEIEEEKVTFMQLHEKVVSVCEHLTHVGVNRGQKVAVLMKNGMEMITVIHALSYVGAVAVLLNTRLSREELLWQMDDAEVICLVTDQDFEAKDIPVYSFAEVMNGPKEEASIQEEFSLREAMTIIYTSGTTGKPKGVILTYGNHWASAVGSSLNLGLRDDDCWLACMPMFHVGGLSLLMKNIMYGMRILLVPKYDADFIHKALQTRGVTIISVVSKMLTDLLERLGEGTYPSSFRCMLLGGGPAPKPLLETCVDKGIPVYQTYGMTETSSQICTLSADYMLTKVGSAGKPLFQCQLRIEKDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRETIQNGWLHTGDLGYLDEEGFLYVLDRRSDLIISGGENIYPAQIEEVLLSHPMVAEAGVVGMTDDKWGQVPAAFVVKSGEITEEEILHFCEEKLAKYKVPKKACFLEELPRNASKKLLRRELRQLVEEM
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: RPOB_CHLSC
Sequence: MLRDGNEGMSTIPGFNQIQFEGFCRFIDQGLTEELHKFPKIEDTDQEIEFQLFVETYQLVEPLIKERDAVYESLTYSSELYVPAGLIWKTSRDMQEQTVFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTGTIISDWGGRSELEIDRKARIWARVSRKQKISILVPSSAMGSNLREILDNVCYPEIFLSFPNDKEKKKFGSKENAILEFYQQFACVGGDPIFSESLCKELQKKFFQQRCELGRIGRRNMNRRLNLDIPQNNIFLLPRDVLAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQFGLALVRLENVVRGTICGAIRHKLIPTPHNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKSSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGHWGSIESPFYEIYERSKEVQMVYLSPSRDEYYMVAAGNSLALNQGIQEEQVVPARYRQEFLTIAWEQIHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLEHQAALDSGVSVIAEHEGKIIYTETNKIVFSGNGDTISIPLVMYQRSNKNTCMHQNPQVQRGKCIKKGQILAGGASTVGGELALGKNILVAYMPWEGYNSEDAVLISERLVYGDIYTSFHIRKYEIKTHVTSQGPERITKEIPHLEANLLRNLDKNGIVMLGSWIETGDILVGKLTPQTAKESSYAPEDRLLRAILGIQVSTTRETCLKLPIGGRGRVIDVRWIQKKGGSSYNPETIRVYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFECSLGLAGDLLDRHYRIAPFDERYEQEASRKLVFPELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIMGKSYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHISQEMLTYKSDHIRARQEVLGTTIIGGTILNPEDAPESFRLLIRELRSLALELNHFLVSEKNFQINRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: A28_YLDV
Sequence: MNPSSVFLIVVATVAICLIVIQVYYIYENYDNIKEFNSTHSLLEYSKTINVFSLDRRIYDPNDHVHDVKQKWRCVNYDNNYVSVSIFGFKSDSGKNIKNFSTVDDCIDYTFSKSTHSNIFNPCINEDKSKDCNFLKSVL
What is the function of this protein?
Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).
What are the official names of this protein?
Envelope protein A28 homolog, Protein 118.
What is the protein family that this protein belongs to?
Belongs to the poxviridae A28 protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Note=Component of the intracellular mature virion (IMV) membrane.
Protein: CCSA_SYNPW
Sequence: MGSFDLQSITSEPVLLLGLAAFALLLTALPWCFWAVSNGRSSSGVRSLLGLSNLLLTAQLVLRWWQSGHFPISNLYESLCFLAWACTLTQLLVERQWPSPLVAASATPMGLGCIAFASFALPDQLQQASPLVPALRSSWLVMHVSVIMVSYAALLVGSLLSVAVLMTDRGQQLELRSSSIGSGAFRKAVSITGETSAVGVQAAPELQLSSIDFSRSEQLDSLSYRTITVGFLLLTVGIISGAVWANEAWGSWWSWDPKETWALICWLVYAAYLHTRLSRGWQGRRPAMVASLGLVVIVVCYIGVNLLGIGLHSYGWFFDA
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: LEUC_ELUMP
Sequence: MPQTIAEKIISNHSGRRVKAGEFVIADVDLTAVQDGTGPLTVEELKKAGFTKLANPARTILFIDHAAPSPRKELSNSQVVLRNFAKETGAILSEIGEGVCHQLLAEKYVNPGEILIGADSHTCTGGALGAFATGMGSTDVAVGMALGKTWLKAPQTFKIEVEGAFKKGVGAKDLILHLIGVIGADGATYKALEFHGSTIRNMEMADRFTLANMAVEAGAKAGLFFTDEKTRAYLAERGRGDNFKLISADEGADYEKVIKIDASSLEPTVSCPHTVDNTKTVGELKDIKVNQVFIGTCTNGRIEDLRIAAEILKDKKVNPGTRTFITPASRDVMLAALKEGLIEIFVKAGASVQTPGCGPCVGVHGGILGDGEVCLATQNRNFQGRMGNTKGFIYLSSPAVAAYSALKGYISDPREILK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: MSRA_CORGL
Sequence: MAWFFAPEPVMVTADEALKGGRHPVLENPAPHTVLGTPVTGPWKEGQQRIWIGLGCFWGVEQMYWQMDGVEGTSVGYAGGFTPNPTYREVCSGRTGHTEIVEVVYDPSKISLEQLVARGLEAHDPTQGFRQGNDVGTQYRSAYYTENEEDAARVKAVVDAYGETLKQHGFGEITTEIGVISPSDYFLAEDYHQQYLDKNPDGYCPHHSTGIPCGVEA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.