PharMolix/UniProtQA huggingface dataset:
Protein: DPM1_DROME
Sequence: MPTNGHKYSILMPTYNEKDNLPIIIWLIVKYMKASGLEYEVIVIDDGSPDGTLDVAKDLQKIYGEDKIVLRPRGSKLGLGTAYIHGIKHATGDFIVIIDADLSHHPKFIPEFIKLQQEGNYDIVSGTRYAGNGGVFGWDFKRKLISRGANFLSQVLLRPNASDLTGSFRLYKKDVLEKCIASCVSKGYVFQMEMLVRARQHGYTIAEVPITFVDRIYGTSKLGGTEIIQFAKNLLYLFATT
What is the function of this protein?
Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
What are the official names of this protein?
Dolichol-phosphate mannosyltransferase subunit 1, DPM synthase, Dolichol-phosphate mannose synthase, Dolichyl-phosphate beta-D-mannosyltransferase, Mannose-P-dolichol synthase, MPD synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: DNAA_CAMJD
Sequence: MNPSQILENLKKELNENEYENYLSNLKFNEKQSKADLLVFNAPNELMAKFIQTKYGKKIAHFYEVQSGNKAIINIQAQSTKQSNKSTKIDIAHIQAQSTILNPSFTFESFVVGDSNKYAYGACKAIAHKDKLGKLYNPIFVYGPTGLGKTHLLQAVGNASLEMGKKVIYATSENFINDFTSNLKNGSLDKFHEKYRNCDVLLIDDVQFLGKTDKIQEEFFFIFNEIKNNDGQIIMTSDNPPNMLKGITERLKSRFAHGIIADITPPQLDTKIAIIRKKCEFNDINLSNDIINYIATSLGDNIREIEGIIISLNAYATILGQEITLELAKSVMKDHIKEKKENITIDDILSLVCKEFNIKPSDVKSNKKTQNIVTARRIVIYLARTLTALTMPQLANYFEMKDHTAISHNVKKITEMIENDTSLKAKIEELKNKILIKSQS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_AZOSB
Sequence: MTDPAGADERFLGAHRLHKTDEFSSVFAFRRALRGRYFMLHYRPNALTTARLGVVVAKKLAKRANVRNLVKRIARERFRRQRTVLPAHDLIVRLHAPVTEASRAALNQDLLQLFGRLPQT
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RF2_ECODH
Sequence: MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAELDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRTSGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_PSEAB
Sequence: MTQSLADMRREYTRDGLSEANAPSDPFSLFRQWFDDAVKTERLPVEPNAMTLATVDADGYPHCRILLLKGLDERGFTFFTNYESAKGRQLAANPRAAMTFFWPALERQVRIEGSVEKVTPEESDAYYQVRPLGSRLGAWASPQSRVIADRAELERLLADTERRFADQPPSCPEHWGGYRLLPQRIEFWQGRPSRLHDRLDYRRQDGGWSRERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RL35_CUTAK
Sequence: MPKMKSHSGTKKRFKVTGSGKVTARKAGKRHLNEHKSSRVTRRLTGETVLSKGEAAKVKKLLAGHPGR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: OST48_PIG
Sequence: MELGAAARAWSLLWLLLPLLGLVGASGPRTLVLLDNLNLRETHSLFFRSLKDRGFVLTFKTADDPSLSLIKYGEFLYDNLIVFSPSVEDFGGNINVETISTFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLAQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKATPGSQRYPQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGEKAPPNAYTVTDLVEYSIVIEQLSEGRWVPFDGDDIQLEFVRIDPFVRTFLKRKGGKYSVQFKFPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMVGLFIFSVVFLHMKEKEKSD
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:11443278).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (By similarity).  Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, DDOST 48 kDa subunit, Oligosaccharyl transferase 48 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the DDOST 48 kDa subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: CCA_BURCH
Sequence: MNIYAVGGAIRDELLGVPVQDRDYVVVGATPEQMTAQGFRAVGKDFPVFLHPQTQEEYALARTERKTAAGYHGFQFHYAPDVTLDEDLARRDLTINAMAREVSPEGALVGPVIDPFDGQADLRARVFRHVSDAFVEDPVRILRIARFAARFADFTVADETLALMRRMVDAGEVDALVPERVWQEIARGLMEAKPSRMFAVLRDCGALARILPEVDALWGVPQRADYHPEVDTGVHVMMVVDYAAKQGYSLAVRFAALTHDLGKGTTPADVLPRHVGHESRSVELLKPLCERLRVPNECRDLALVVAREHGNLHRVMEMGAAALVRLFERSDALRKPARFAELLQACESDARGRLGLDAQPYPQAERLRVALAAARSVDAGAIARGIGNDTEKIKEAVHRARIQAVAQALAIGE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RS11_ALTMD
Sequence: MAKAPARSTRKRAKRQVADGMAHIHASFNNTIVTITDRSGNALAWATSGGSGFRGSRKSTPFAAQVAAERAGVAAQEYGLKNLEVFVKGPGPGRESAIRALNATGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MUTS_TREPA
Sequence: MRSLASDTPLMRQYHAIRAQHPDAVLFFRLGDFYEMFDSDALHVSTLLGLTLTKRNGTPMCGVPVHTARTHIARLLKHGKKVALCEQVSHPVPGELTQRKVIEIISPGTAVEDDFLSQGFSQYLATVCASDATVAFSYLEVSTGAFFITSFPRAEAADALQKEFGRVQPSEVLLSASVLRSLPELAAILSLYPRLVRTTGADALFNPEHTKNRLHHCFRTRNLDCLTLLPHSPDLAAAGALIAYLEETTRHPLSHVSAITRYHIHDFVEIDDATRKNLEILQNLHDSTHAHSLFETLNYTHTAMGTRLLRYWLHHPLRSQEEIQKRLSAVVFFHHRPHILKTLRATLSCVRDVERLVARVALEKAHGRDLLALKESLRAILTFRSLERESPFPPDLLPSEGDTPVLQELYGLLEQSIKEDCPVTLSDGNLIKRGFSASLDELHRVRDNANEILKQYLAEERERTGIGTLKMKYNRMLGHFLEVSKGHLSAVPAHFIRRRSLSNADRFTTEQLSELEAKLARAREGLVSFEQELFADIRRTVCSHTQLLRTNAARVAQLDVLQSFAHAALQHGWSQPVFIKDGALRITGGRHPVVELHLPSGEFVPNDLTLSSSEHAVLPRFALITGPNMAGKSTFLRQTALICLIAQVGSFVPAEKAELTPVDRIFCRVGAADNLARGESTFLVEMSETAHILRAATRDSLVIMDEVGRGTATEDGLSIAQAVSEYLLHHVRAKTLFATHYHELSRLAHPQLEHLKLDVLETDNTIVFLKKVTPGSCGSSYGIYVARLAGLPESVLARACELLKQLQQRAGSAPRASAAHEADAVAQTEAVHAHKAASKPCAQRVSADLFTQEELIGAEIASLNPDAITPLEALTLIARWKRSLRGSATQQSSAMTKRKG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RPPH_XANOR
Sequence: MIDPDGFRPNVGIVLMRQDGQVFWARRVRRDGWQFPQGGMNTDETPVEAMYRELREETGLLPEHVELLGATPGWLRYRLPSRAVRRNERQVCIGQKQVWFLLRFTGDESHLKLDHTDTPEFDHWRWVDFWYPVEHVVMFKRGVYARALRHLAPIAQNLAGPAAVGAMPERALEAWLPGSSAAGHDSPRKRPRKRSGARPMRINND
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: Y485_MALP2
Sequence: MKELDLSQISLLIDFYGNLLTDKQLQNLIDYYFNDLSLSEIAANNNVSRTAIHDSIKKSKNELEQFENKLKFIYRFNLRKEIYKQIKDNNLLDQLLETEVEQLWKTK
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein MYPE4850.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: DNAK_SHEWM
Sequence: MGKIIGIDLGTTNSCVAVLDGDKARVLENAEGDRTTPSIIAYTGEETLVGQPAKRQAVTNPTNTFFAIKRLIGRRFKDDEVQRDVDIMPFKIIGADNGDAWVEAHDKKMAPPQVSAEILKKMKKTAEDFLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAYGIDKKQGDNIVAVYDLGGGTFDISIIEIDSVDGEQTFEVLATNGDTHLGGEDFDNRLIKYLADEFEKEQGMNLRNDPLAMQRLKEAAEKAKIELSSTTQTEVNLPYITADASGPKHLVVKVTRAKLESLVEDLVTRTLEPLKVALADADLSVSDVNEVILVGGQTRMPKVRAEVSAFFGKELRQDVNPDEAVAIGAAVQAGVLSGDVKDVLLLDVTPLSLGIETMGSVMTKLIEKNTTIPTKASQTFSTADDNQAAVTIHVLQGERKQSSGNKSLGQFNLEGIEPAPRGMPQIEVAFDIDADGILHVSATDKKTGKAQNITIKASSGLSDEEVEAMVRDAEAHADEDAKFEELVTARNQADGMVHATKKQIEEAGEALPAEDKEKIETAMSAVETAVKGSDKEAIEKSTQELMEASSKLMEIAQAKAQAEQGQQAPEGEAQAAKPDEDVVDAEFEEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RIPR2_HUMAN
Sequence: MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGHKNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEINRSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKIEVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVDINDLGTIKLNLEITWYPFDVEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFFRWLHPSPDKPRRLSVLSALQDTFFAKLHRSRSFSDLPSLRPSPKAVLELYSNLPDDIFENGKAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDDTSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEALLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFLDGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESALESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTEDTGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQIQVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEASFARTVNKEYPGLADPVFRTLVSQILDRAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLESYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEAVTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSDTEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF
What is the function of this protein?
Acts as an inhibitor of the small GTPase RHOA (PubMed:25588844).  Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation (PubMed:17150207).  Maintains naive T lymphocytes in a quiescent state (PubMed:27556504).
What are the official names of this protein?
Rho family-interacting cell polarization regulator 2.
What is the protein family that this protein belongs to?
Belongs to the RIPOR family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, filopodium. Cell projection, stereocilium. Cell projection, stereocilium membrane. Apical cell membrane. Note=Localized in the cytoplasm in cells undergoing mitosis (PubMed:17150207). Colocalized with F-actin (PubMed:17150207). Localized with RHOC within the basal domain of hair cell stereocilia, near the taper region (By similarity). Detected in punctate pattern forming a circumferential ring at the stereocilia base (By similarity). Localized to the apical stereocilia of inner and outer hair cells (By similarity). Not detected as a membrane-associated protein in stereocilia (By similarity). SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Note=Accumulates at the leading edge of polarized neutrophils in a chemokine-dependent manner (PubMed:25588844).
Protein: PQQB_PSEMY
Sequence: MQIQILGSAAGGGFPQWNCNCRNCRGVRAGTLRAQPRTQSSIAISDEGEQWILCNASPDIRAQIEAFPALQPARKLRDTAIAGIVLLDSQIDHCTGLLTLREGCPHQVWCTEMVHQDLTTGFPLFNMLSHWNGGLQHRLIELDAKPFSIPACPGLRINAIALRSSAPPYSPHRGNPHPGDNIGLFIEDLRTGGTLFYAPGLGQVDEQLLGWMRRADCLLVDGTLWRDDEMRVCEVGDKLGSEMGHLCQSGPGGMIELLDGLPTARKILIHINNTNPILDLDSPERAELDAHGIEVAFDGMSIVL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: CARB_STRPS
Sequence: MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMELSKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAATIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALKIEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAELTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQLRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIKSDKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQPPGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDHPVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQETIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVATKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSDATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAAFFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEHGVPLFTALDTANAMLKVLESRSFVTEAI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: NADK_CLOB6
Sequence: MKNIGININTDKDISRNILDKIFQYIHEECSEAKIKVFYDSKGLDNEESRALDAVMVLGGDGTILGTARALAKYDVPIFGINRGHLGFLAEIELEDCKKAIKNLFKGQYKIEDRIMLKCDLKGIDKKDDFLALNDIVLTKGNLSRIVKYSIYVDDVWYTTFVADGVIVATPTGSTAYSLSAGGPIVYPDLDVLEIAPICPHSLGIRPILLNGNSKINIRVLKKYEDPVLTIDGQRYKKVTVNEVTISKSKYKCRLIKFKDKDYFKILRTKISYRSRECEGE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPL1_CANGA
Sequence: MENKATLARNIGEKRVSPRSKVNGTGKSWRISYSPQRMDGVSSGRNVSKIPSPVRERLFLKNQERKPLGVSPLSNLSPNSLGRNSLEKSTYNNKLSLKDFEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQLGMDHPNIIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALHYMHKKRIIHRDVKPENVLIGFDNVVKLADFGWSILNPEGSKRKTLCGTIDYLSPEMITPREYDEQVDVWALGVLAYELVVGVPPFEENSKELTYKRILKCDLNFPESISKDAKDLISKLLVTDTTQRLSLTGVKTHPWILKNKPFW
What is the function of this protein?
Required for high-fidelity chromosome segregation during the later part of each cell cycle.  Acts in opposition to the phosphatase PP1.  Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles.  The promotion of bi-orientation is achieved by selectively detaching kinetochore-microtubule attachments that are not under tension.  Phosphorylates histone H3 to form H3S10ph during mitosis and meiosis (By similarity).
What are the official names of this protein?
Spindle assembly checkpoint kinase, Aurora kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and on elongated and disassembling spindles. Also associated with the kinetochore (By similarity).
Protein: NIT4_NEUCR
Sequence: MNSSDVQMMSSQDAPGSAGLAPDNIASSLPSKKKSRRGADPTNQKRRCVSTACIACRRRKSKCDGALPSCAACASVYGTECIYDPNSDHRRKGVYREKNDSMKAQNATLQILIEAILNASEEDVIDIVRRIRTCDDLDEVAESIRRDEKNATATNDNDDSDEPTQPGRDDATSQAVEGERDLARKMGELRIENGSVRFIGGTSHLIYLSEPTDASEEPELETRLSTCDENPITTWTEVTKNPQLIIHLVNMYFNWHYPYFTTLSRSLFYRDFIKGKPAGQPRSTVYCSSLLVNAMLALGCHFTSVDGAFAVPGDSRTKGDHFFAEAKRLIVQNDEYEKPRLTTVQALALMSVREAGCGREAKGWVYSGMSFRMAQDIGLNLDIGSLDEKEVDARRITFWGCFVFDKCWSNYLGRLPQLPKNTYNVPKYDVFPDEDAELWSPYTDAGFDQSCKQPSRTRAIGLQLSKLCEISSDLLLFFYHPSHIGRSSGKSAELKKLSELHRRLEDWRTELPKEFEPKDGQLPNVILMHMFYHLQYIHLFRPFLKYTKEASPLEKVQPRRICTTNANSISKLMRLYKKLYNLRQICNIAVYMLHSACTIHMLNLPEKTARRDITHGVRQLEEMAEDWPCARRTLGIISVLARKWNVELPEEAAIVLKRTDEKYGMFSTSEVPSPNRTAPSLAPSSPAPPYTPEASLLFSTTAAAVLEQQPYSPMTLYSHPTPPHLGPESISDPGMSPNIVTFSDLPDPSAPIIPQQQQNMQAISSLSQNNMLHQHHHHLQNQHQPQQPHHNHMTYQQQQHNLLTHPVSASSMSMSDTLATITAWGIPTSSPGNNNNNNIVSQHPHHQKQPQQQQQPQAQRYPTVGSVGTNTVKPPAAATQTFTPAQLHANNLATATRSTASNHKSVGRHVSPSSIYAIDGQDWYLKDGVTWQQGFQGWDLEGGGAGTATSTGGIGDGGGPTGGAGDSMARLAPRGNIGGGGGGGGGSTGQRQQQQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQEANMFAYHHGAERGGGGIESTGMGMTTVGGGGGGFDPIGGSGLLDDLVGLDELGSLDGLGHLPGLD
What is the function of this protein?
Pathway-specific regulatory gene of nitrate assimilation; it activates the transcription of the genes for nitrate and nitrite reductases.
What are the official names of this protein?
Nitrogen assimilation transcription factor nit-4.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOZ_ECO5E
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: AMT3_ALTAL
Sequence: MVAWNGTLVRPKLLIGASCQCVYNIYLHPLRHYPGPKLAAATGLYHWYWTLAGRIHRQLHKLHRQHGEVVRIGPDRLSFIAPEAWKDIYGPGTTSHKENKKDGRFYAPTPNGRRAMISLLDNQHHASVRRVFQPAFSDRSLRALEPVINKHVKRLMHTNLRQLARADEPFDLVHLLNCAIFDIMGDLMLSESFGMLEQSAYVEWIETLLVALRYESVGQFLLEYATLGKLLSFLMPPSARRKREQHVQYTAQRVDKRQQKSEATKRDIWGFLAAHENAEMLDIEDKHANASLFMVAGTETTITALSGLVFLLLQHPPCMRRLVAEIRDSFTCEDAINMDTLQGLSYLNACLSEALRLYPPVPLGNPRVTPADGNVICGHAVPGHTRVYVSTWAACRSASNFGDADSFMPERWLPDSGYDSDRKEASKPFSYGPRNCIGKSMAYHNIRIIIARILWNYDLLAAAESDGWMKQECFPLWDKKPLMVRVMLR
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene clusters that mediate the biosynthesis of AM-toxins, host-selective toxins (HSTs) causing Alternaria blotch on apple, a worldwide distributed disease (PubMed:17990954).  AM-toxins are cyclic depsipeptides containing the 3 residues 2-hydroxy-isovaleric acid (2-HIV), dehydroalanine, L-alanine which are common for all 3 AM-toxins I to III.  The fourth precursor is L-alpha-amino-methoxyphenyl-valeric acid (L-Amv) for AM-toxin I, L-alpha-amino-phenyl-valeric acid (L-Apv) for AM-toxin II, and L-alpha-amino-hydroxyphenyl-valeric acid (L-Ahv) for AM-toxin III (Probable).  AM-toxins have two target sites for affecting susceptible apple cells; they cause invagination of the plasma membrane and electrolyte loss and chloroplast disorganization (PubMed:22846083).  The non-ribosomal peptide synthetase AMT1 contains 4 catalytic modules and is responsible for activation of each residue in AM-toxin (PubMed:10875335).  The aldo-keto reductase AMT2 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV), one of the precursor residues incorporated by AMT1 during AM-toxin biosynthesis, by reduction of its ketone to an alcohol (PubMed:15066029).  The cytochrome P450 monooxygenase AMT3 and the thioesterase AMT4 are also important for AM-toxin production, but their exact function within the AM-toxin biosynthesis are not known yet (PubMed:17990954).  Up to 21 proteins (including AMT1 to AMT4) are predicted to be involved in AM-toxin biosynthesis since their expression ishighly up-regulated in AM-toxin-producing cultures (PubMed:17990954).
What are the official names of this protein?
Cytochrome P450 monooxygenase AMT3, AM-toxin biosynthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y2181_ARATH
Sequence: MAITAYDALTERQKAPKVLLINDFAISSSSSSPPFFNLAATFRDNIRSFLREYAEIEDYTIDGATVSTIFLGSQANGVVFPLYIIEQQISDSSPNPLCDFCRCFGWGHHYVTKRKYHMIIPNRDEWNEPLKRESLTLSSHLMHGLIHCNGFGHLLCINTDLDDPNHLSGDQIMDFWDRLCSTLHTRKISLDDTSKKGAMDLRLLHGVAYGRPWFGKWDYMFSHGSFGVKKDLYWRAILTLSSIEVDKILEELSGTSKGRVMKKIIDFYRGSTESPLATLSDLLRFMLGFISKAPIERKTAMALVAMSLDHVSYPTLRADENSEVCTSPDQESDDNGYESGRDTVLDDHNTTTSGIKPPQYYSFDDLSRREHSRWPGRRLNDAAQAVLKVFKERNSTISRQDLREAVRSSIGDTGLIDFLLKHIDKVLIGDQIVQRSTNPKSRMLQFSLRTINSRVQEQKRKKKRKVKPQETSECTSTTPGLSPYDDILYLYQNLLLTYPDSDLYSEASQVILKCKSFVKEWSYQEQNHLTVSCQVLPNHEELLRDFTRLLPPGDLVAVPENATIRELKSAAEKVLRDTYCITETFEVLEIRNRYLEKLDDNVSLKSQGNTEFMVKGFGLDIGTELRYEGGFDDWTVDCKCGARDDDGERMVACDACKVWHHTLCNSIEDDEAVPSVFLCNMCYGDSLRSKKRNLSIR
What are the official names of this protein?
PHD finger protein At2g01810.
What are the subcellular locations of this protein?
Nucleus.
Protein: RRF_THIDA
Sequence: MAETTITDIKQSAEQKMGKTLEALKNDLAKVRTGRAHAGILDHVLVDYYGNPTPVPQVANVSLVDSRTLGVQPYEKNMVGKIEKAIRDGDLGLNPATHGDVIRVPMPALTEERRRDLIKVVRNEAEGARVAVRNIRRDANASLKDMVKAKTATEDEERRTQDEVQKLTDKFIGEIDKMLAEKEKDLLAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.