PharMolix/UniProtQA huggingface dataset:
Protein: GRPE_VIBVY
Sequence: MSNEENKINEEALKQQDAAEVEVEAVGTDADIEWNEEADESAVKIAELEAALLASEARVKEQQDSVLRAKAEVENMRRRTEQEIDKARKYALNRFAEELLPVIDNLERAIQAADAESEAVKPLLEGVELTHKTFVDVVSKFGLKEINPEGQPFNPEWHQAMSIQESPDHESNTVMFVMQKGYELNGRVIRPAMVMVAK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISAB_STAAW
Sequence: MNKTSKVCVAATLALGTLIGVTVVENSAPTSKQAQAAITPYYTYNGYIGNNANFILDKNFINAIKYDNVKFNGIKLAKTNTIKKVEKYDQTFKGVSAKGNEASQLQFVVKNNISLKDIQKAYGKDLKKENGKTKEADSGIFYYQNAKKTLGIWFVVDHNRVVEVTVGHTPYKTSK
What are the official names of this protein?
Immunodominant staphylococcal antigen B.
What is the protein family that this protein belongs to?
Belongs to the IsaB family.
What are the subcellular locations of this protein?
Secreted.
Protein: TATA_SPHAL
Sequence: MGSFSIWHWLVVGILVLLLFGKGRFSDMMGDVAKGIKSFKKGMSEDDAPTPAPKQIDAQRAPDLSATPTPTAETENR
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LEU1_WOLSU
Sequence: MSAEMIKIFDTTLRDGEQSPGASMNTEEKIRIAKQLERLGVDVIEAGFAAASPGDFDAISKIASAVSESTICSLARAVEKDIKAAADSLAPAKLKRIHTFIATSPIHMEYKLRMTPSEVIKRAVEAIAYAKSFMEDVEFSCEDAGRSDVGFLKEILAAVIEAGAGTLNIPDTVGYRLPHEMGAIIKELHEFVGNRAILSVHCHNDLGLAVANSLYCIQSGARQVECTVNGLGERAGNAALEEIVMAIKTRRDIFGGLDTRINTKEIYASSQLVANITGIRPQPNKAIVGKNAFAHESGIHQDGVLKHKETYEIMHASDIGLGEQESIVLGKHSGRHAFKDKIKALGFEVSYEELNAAFDRFKALCDQKKEIYDEDIRAILAEETSHIPKVYELVGIQLSDCSMGRPYAAITLKKEGSEEIVDAAIGNGSVDALFKTIDRISQIKGELKDYKVEAVTQGKDALAKVVVKVEFEENKPAIIGHGLHIDTMLATAKAYVGALNSYLSMRELMGKKKCEEERI
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: PDXJ_SHEON
Sequence: MSRILLGVNIDHIATLRQARGTSYPDPVHAAAVAEHAGADGITIHLREDRRHIIDRDVYLLAKTLKTRMNFECAVTEEMLNIACEVKPTYVCLVPEKRQEVTTEGGLDVAGQLDKITAAVSRLAANGIQVSLFIDADKTQIDAAVASGAPLIEIHTGCYADAKTADEEAKELERIREMAKYAHGKGLIVNAGHGLHYHNVKPIAAIPELYELNIGHAIVARAAIDGLATAVKDMKTLMLEGRRGE
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_ELUMP
Sequence: MNNIINEDLKNRILKEMETVFGVEACETWLKPLSLSLKNDILTVTLPNKFWSKTIADKYVQEVKSSIEKEQGGDIQIKYDVLEDTTPYKRPEIPPQVMGANYNAKIPFPSRLNPNYTFEGFIEGPSNRFAYRAAEAVVKKLGERENNPLVIYSTPGLGKTHLLHAIGNRILKENPYAKILYMSGEEFVSEYIESLQNRNPEAFRKKHRSLDCFLMDDIQFVAGKESSVQEFFYTFNALFESKKQIVLTSDRTPQQLGIDPRLSSRLLSGIVSEIKRPDLETRIAILRQKRDTSNFDVGDDVIAFIAEGVQASIRELEGCLFRLTTYCNIHGVTPTIPIAREVLSDIISMEEKRLLINPNSIKKVVSKHFKIDIIDFNSKRKNHSIAWPRQIAMYLATELTDMSLPEIGREFERDHSTVVHAREKIKEEIENDPFFAAQINQIISDIKAVDKR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTH_SALAR
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCFLSGLGGTLFDPPRSALVVKLIRPEQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCAMGAILFIVCAIFNAWLLPAWKLSTVRTPVREGMRRVISDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDVAGSPAAVKWMYAIEACLSLTLLYPIARWSEKRFRLEHRLMAGLLIMSLSMIPIGLAGNLQQLFTLICAFYIGSVIAEPARETLSASLTDARARGSYMGFSRLGLAIGGAIGYIGGGWLFDMGKTLAQPELPWMMLGIIGFITFLALGWQFSHKRTPRQYTGARRLI
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBEY_SALG2
Sequence: MSQVILDLQLACENHAGLPDEAQFQRWLDGVIPQFQEEAEVTIRLVDETESHDLNLTYRGKDKPTNVLSFPFEAPPGIEMPLLGDLIICRQVVEQEAQEQSKPLEAHWAHMVVHGSLHLLGYDHIDDDEAEEMESLETEIMLAMGYEDPYIAEKIAE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OGA_HUMAN
Sequence: MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL
What is the function of this protein?
Cleaves GlcNAc but not GalNAc from O-glycosylated proteins.  Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro), but has about six times lower specific activity than isoform 1.
What are the official names of this protein?
Protein O-GlcNAcase, OGA, Beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase, Beta-hexosaminidase, Meningioma-expressed antigen 5, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase, NCOAT.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 84 family.
What are the subcellular locations of this protein?
[Isoform 3]: Nucleus. SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm.
Protein: DAPH_CLOPE
Sequence: MSYNFTDPYEIARFIKEVKKSTPVKVYLKGNLEGVELGSIECYGNNDFYVLFGESDEVATFLTENKDKIVSFRLENDRRNSAIPMLDLLNINARIEPGAIIRDRVSIGDNAVIMMGAVINIGAEIGESTMVDMNAVIGARGKLGKRVHLGAGAVVAGVLEPPSKTPCIIEDDVLIGANAVILEGVKIGKGSVVAAGSVVVEDVPAGVVVAGTPAKIIKSVDEKTKDKTEILDDLRK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: NIFH_GLUDA
Sequence: MSKLRQIAFYGKGGIGKSTTSQNTLAALVEMGQKILIVGCDPKADSTRLILNAKAQDTVLSLAAEAGSVEDLELEDVLKIGYKGIKCVESGGPEPGVGCAGRGVITSINFLEENGAYDDVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMALYAANNIAKGILKYAHSGGVRLGGLICNERQTDREYDLADALAKRLNSKLVHFVPRANIVQHAELRKQTVIEYAPDSAQAGEYRTLAQKIHANSGQGTVPTPITMEELEDMLLEFGIMKTDEQALAELAAKEAKAAAALA
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: METN_STRGR
Sequence: MITTTGLTKVYQSRDREVTALDGVDLHVREGEVYGVIGQSGAGKSSLIRCVNLLERPTSGTVTVAGQDLTALAGRGRRASAELRRARTRIGMVFQHFNLLGSRTVLDNVELPLEILGVSGRDRTRKAGELLDLVGLADKAKAYPGQLSGGQKQRVGIARALAGDPQVLLSDEATSALDPETTRSILQLLRDLNQQLGLTVLLITHEMDVVKTVCDSAALMRRGRIVESGTVAELLATPGSELAHELFPVGGTASGPDRTVVDVTFQGESASRPVISQLSRTYNIDISILGAAMDTVGGRQIGRMRIELPGRFEENVVPIGFLREQGLQAEVVEDETGPQAATVVPEQTPAALTKEVVK
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: XPKA_LACPE
Sequence: MSTDYSSPAYLQKVDKYWRAANYLSVGQLYLKDNPLLQRPLKASDVKVHPIGHWGTIAGQNFIYAHLNRVINKYGLKMFYVEGPGHGGQVMVSNSYLDGTYTDIYPEITQDVEGMQKLFKQFSFPGGVASHAAPETPGSIHEGGELGYSISHGVGAILDNPDEIAAVVVGDGESETGPLATSWQSTKFINPINDGAVLPILNLNGFKISNPTIFGRTSDEKIKQYFESMNWEPIFVEGDDPEKVHPALAKAMDEAVEKIKAIQKNARENDDATLPVWPMIVFRAPKGWTGPKSWDGDKIEGSFRAHQIPIPVDQTDMEHADALVDWLESYQPKELFNEDGSLKDDIKEIIPTGDARMAANPITNGGVDPKALNLPNFRDYAVDTSKHGANVKQDMIVWSDYLRDVIKKNPDNFRLFGPDETMSNRLYGVFETTNRQWMEDIHPDSDQYEAPAGRVLDAQLSEHQAEGWLEGYVLTGRHGLFASYEAFLRVVDSMLTQHFKWLRKANELDWRKKYPSLNIIAASTVFQQDHNGYTHQDPGALTHLAEKKPEYIREYLPADANSLLAVGDVIFRSQEKINYVVTSKHPRQQWFSIEEAKQLVDNGLGIIDWASTDQGSEPDIVFAAAGTEPTLETLAAIQLLHDSFPDMKIRFVNVVDILKLRSPEKDPRGLSDAEFDHYFTKDKPVVFAFHGYEDLVRDIFFDRHNHNLHVHGYRENGDITTPFDVRVMNQMDRFDLAKSAIAAQPAMENTGAAFVQDMDNMLAKHNAYIRDAGTDLPEVNDWQWKGLK
What are the official names of this protein?
Xylulose-5-phosphate phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: ACSL3_RAT
Sequence: MNNHVSSTPSTMKLKQTIHPILLYFIHFIISLYTILTYIPFYFLCESKQEKPNHIKAKPVSSKPDSAYRSVNSMDGLASVLYPGCDTLDKVFMYAKNKFKDKRLLGTREILNEEDEIQPNGKVFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGVIVHTMAAVQALGVKADVDKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRVLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFNGTWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK
What is the function of this protein?
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:28209804, PubMed:19737935, PubMed:15683247).  ACSL3 is required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins) (By similarity).  Has mainly an anabolic role in energy metabolism.  Mediates hepatic lipogenesis (PubMed:19737935).  Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (PubMed:9276691, PubMed:8663269).  Both isoforms exhibit the same level of activity (PubMed:9276691).
What are the official names of this protein?
Fatty acid CoA ligase Acsl3, Arachidonate--CoA ligase Acsl3, Brain acyl-CoA synthetase II, Long-chain acyl-CoA synthetase 3, LACS 3, Long-chain-fatty-acid--CoA ligase 3, Medium-chain acyl-CoA ligase Acsl3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: LOLB_SALPC
Sequence: MTLPDFRLIRLLPLASLVLTACTLPGHKGPGKSPDSPQWRQHQQEVRHLNQYQTRGAFAYISDDQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEVNYRQDGKNWKVVYGGYDSKTQPAMPANMELSDGSQRIKLKMDNWIVK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: MIAA_STRPB
Sequence: MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQLDIGTAKATQEEQEAAVHHLIDIREVTESYSAYDFVQDAQKAISDIVSRGKLPIIVGGTGLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIRALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVNRMLENGLLEEAKWLYEHYPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAITAPDYPQVVHDRVRDFLGQKEKS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: THIC_ECOL6
Sequence: MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITATQPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CCA_YERPA
Sequence: MNIYLVGGAVRDSLLNLPVTEQDWVVVGATPEQLLKLGYQQVGKDFPVFLHPVSHEEYALARTERKSGQGYTGFTCYAAPDVTLEDDLLRRDLTVNAIARSADGEFIDPYHGKQDLENRVLRHVSDAFGEDPLRVLRVARFAARFAYLGFTIAPETMSLMSNMAQSGELSALTPERVWKETEKALKTQSPHVYFQVLRDCGALAVLFPEIERLFGVPAPEKWHPEIDTGIHTLMTLAIAAQLSPEVDIRFAALCHDLGKGLTPKEHWPHHHGHGPAGVKLVEQLCQRLRIPNPVRDLAKLVAEYHDLIHTVNKLRPETLLKLFNAIDVWRKPERLEQMIMTSEADARGRTGFENNPYPQGDYLRAAFQIANGVSIQEVVASGLQGLAIRDELQRRRQQALAEWKQTQETASI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: CI163_HUMAN
Sequence: MPGPLTCTPAWQGQGRAAAFLCCSFQRAGAVVGVPARWHRGRLSSQQRLRSSLGGSHPCPQLGRRLVREGVISVPRQQGRRRCRESFSPADVAPGPICSANICLSGVRFLTCLNRVREHVVGPSPSPAAPICFFPVVEALCTLRGRRCHCLPFPKRGMQRWMLPLRRGARLLPLASSKNPRARSPGLDPLGSSETLWSHRGGH
What are the official names of this protein?
Uncharacterized protein C9orf163.
Protein: APT_BIFLO
Sequence: MAQSDITIDALSKVGQQDAEYLVSLVRSVPGFPKEGIIFRDFMPVLADPKGLKILLKALEEALPVSPSEFDSIAGLESRGFLFGPVMAAHLGKGFIAVRKAGKLPPETIGESYDLEYGTASVEIETDAVQAGKRVLIVDDLIATGGTAKAATDLIEKAGGTVVGFSFVMRLDGLDGLDKLDGKPSSSLIAMPA
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMSS_YERE8
Sequence: MQNPTIVIGVIGADCHAVGNKVLDRVFTMHNFSVINLGVMVSQDEYIDAAIETGAQAIVVSSIYGHGEVDCIGMRENCVERGIGEILLYVGGNLVIGKHDFSEIETKFKGMGFNRVFAPDTDLELVCSLMKRDIERVMQSEEAPEGMQ
What is the function of this protein?
Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
What are the official names of this protein?
Glutamate mutase sigma subunit, Glutamate mutase S chain, Glutamate mutase small subunit, Methylaspartate mutase.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate mutase GlmS subunit family.
Protein: MSHC_MYCBO
Sequence: MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: PP85_HHV6U
Sequence: MVTHAMEEPKTFNIPTFVLDENCNFIPEVLSRANAKYIKDVLIQDSYNTVCLANSFIPMTIQTAEQIMVIITKFKFSRARDLFEKVLRLGVHINRFYAGKKQVKHMITMMKSLFDTEEAMRRLDRALMGLFVDARGSSYMPLIALSLHENGLPDSKFTKAVKLINTTLNSFHNRPDADIEQYAQKLRAYNYLYKIPHYTLKEAVDVYSENLKDLSIGVNKKPTLLFTSSDDGYLSHIFNDMLFLTSTWNMIYNCKVQIRRLTTWIKYEINSIVEDCVLVGFQLPDLKDTILDLAALTSNMNLVDPDKDLFSHYKLILEKLFEISIFATKANICILPTFIKSHLIEFEDVLKRSNDDEDLNYLLLKSNDSDDEYDEDKLPIQVDPGRVDNVLTDSNFFNVTADNAFSSIAIMPISYDKIIDVEENVIQVLEVEMQSLSAVVYGAVANKYGLSLPQVIKRLNQNEGRASSRASSSHSTSTIPYSPPQSGRSTPTSILRQRAPIRSNSRSSSVSFSQDDDNRSHYSDETNISDYSYPMADLDLEDEEPMEDHPHSPQSASSNNSMSRRSRALQNEQRRRTPTMAPPSPARGQNNARLRRRTRRSTETNDERL
What are the official names of this protein?
Phosphoprotein 85, pp85, Protein U14.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae pp85 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Note=Expressed exclusively at the cytoplasmic level during the late phase of the virus replication cycle. Also found in dense bodies (By similarity).
Protein: KCO3_ORYSJ
Sequence: MDTEPLLSPLSPSPHLLHPLPEHAEVSTFSPPLSPCPSPASSYKERIIFGAHPPPPPPPPPPPPPPPRGRRYYRRVSGDDLDVPSCSSSPSPPSDEENPPPNPPSLFDFIGGRTNLHRSRTAPAMAPLNAAAIAAAAASGDSRNPPPPPRRPAIVLHAFLFLLAYLAMGVTFYAALPGNFTSSAGPTHPVADALYFCIVTLCTIGYGDITPATPAAKLFSISFVLIGFGFVDILLSGMVSYVLDLQEHLLITALKNPRSVRKHRHNYIFDLKKGRMRVRMKVALALTVVAICVGVGAAVLKRVENLGWLDAVYLAVMSVTTVGYGDHAFRTLAGRLFASAWLLVSTLAVARAFLYLAEMRIDKRHRAMANWVLSRDMTVSEFLAADIDNNGYVTKSEFVVYKLKEMGKISEKDIMMICDQFQRMDSGNCGKITLSDLLESHQLVTDLNEKKKGKKS
What is the function of this protein?
Inward-rectifying potassium channel.
What are the official names of this protein?
Two pore potassium channel c, Two K(+) channel c, Calcium-activated outward-rectifying potassium channel 3, OsKCO3.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.7) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CDKG1_ORYSJ
Sequence: MAAGSHGGYRGYEVAREREHDVGVSRRSKEHYHHRHPSRHRDSERRRDGGRSGGRELSNGYSHRRDSPRPPPRRRPSEGRTEDREPGEVSGGSGSERSGERPMKTGEPRENGVTRVSKEEAKMSPSKKRKQSPVIWDRNGSKRQARDPVRGIREVDAVVAEIIMHQSHSLPVMSSLSSIGDGHSPMILDVSVDKVQEYEKNRIVDEEEEGYPTMRNILTSRWADAGDEEENVFVPKKKKSVSPVDSIERGSTKKVTSPESGEVLVYNSVRSSSRSSDSGVLQGSANRDLEVEKGDNIDVEEAADDDYPAGHLLDSDFEGEDCRSETPECTRSPRRCINMLQGCRSVDEFERLNTINEGTYGVVFRVRDKRTGEIVALKKVKMEKEREGFPLTSLREMNILLSFHHPSIVEVKEVVVGSNDRDIFMVMEYMEHDLKGVMETMKQPYSQSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLSRQYGSPLKPYTQLVVTLWYRAPELLLGAKDYSTAIDMWSLGCIMGELLSKGPLFNGKSEIDQLDKIFRTLGTPDENIWPGYSKLPGATVKFGKQTHNRLRDKFRAVSFTGGPMLSEAGFDLLNRLLTYDPEKRISAEDALNHEWFRELPLPRSKDFMPTFPALNEQDRRFKKHMKSPDPLEEQRMKEQGNNGDRGLFG
What are the official names of this protein?
Cyclin-dependent kinase G-1, CDKG;1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: IF2P_AERPE
Sequence: MAGDKGGGDGERRLRQPIVVVLGHVDHGKTTLLDKIRRTAVAAKEAGGITQHIGASIVPADVIEKIAEPLKKVIPVKLVIPGLLFIDTPGHELFSNLRRRGGSVADFAILVVDIMEGFKPQTYEALELLKERRVPFLIAANKIDRIPGWKPNPDAPFIETIRRQDPKVREILEQRVYEIVGKMYEAGLPAELFTRIKDFRRKIAIVPVSARTGEGIPELLAVLAGLTQTYLKERLRYAEGPAKGVVLEVKEMQGFGTVVDAVIYDGVLKKEDIIVVGGREGPIVTRVRALLMPAPLQDIRSREARFVQVDRVYAAAGVRIAAPGLDDVIAGSPIYAAESEEEARKLMEAVQREIEELRFRTENIGVVVKADTLGTLEALVEALRRRGVPVRLADIGPVSRSDVLDAAVTRKIDPYLGVVLAFNVKVLPEAEEEASRAGVKIFRESMIYKLIEDYEEWVKKEKEAERLKALNSLIRPGKFRILPGYVFRRSDPAIVGVEVLGGVIRPGYPVMDSQGRELGRIMAIKDRDRSLEEARLGAAVAVSIQGRILIGRHANEGDILYTNVPAQHAYKILTEFKDLVSKDELDVLREIAEIKRRAADHEYNKVLLRLKIKRVSQ
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2 (By similarity).
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.