PharMolix/UniProtQA huggingface dataset:
Protein: GCYB1_CANLF
Sequence: MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETTQDDN
What is the function of this protein?
Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
What are the official names of this protein?
Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALIX_DICDI
Sequence: MLSIERKRTEKVDFSKPLTKYIKEQFSKAESDQHETQIATLNGLREDVRNLQERTETSKEMVWKYYSILSSLELRFPISENNVRISFPWTDSYRQRKSTLYSIYFERASVLFNYGSIVSQIASSTNRSNIEGVKKACNQFQLAAGVFNKLREYASLHPECSTSADFSSESLQALVTIMLAQAQECIYEKASMDNLSDSILSKLAAQVAEYYDTFNQLLNSNSLKSIVDRNWNITATVKSYLYKAISLYCHAKGLEQVSQFGEQVSRLMIAVDNINQSKVNLAKTAPIELKEIVERYVISITRYCESAKKDNDTIYHDTIPPAHKLTPIEKKPLAKALPLPEINFVDPFNSLVPFSVKEDSAYYNDQKETLLRKELDNIEFHNQSAKASLLSMGLPGSIEALDVGVPVALKEKMNVVTNEQGVSNITRLLENIQQLSDEDSAICLSAGNLLKKEEDEDNLMRATYGAQWHRTPSYTLTANLTQDYAKYTSHLQHSTKSDSFIRKKFEDHKNSIQELENQTEIIALLPTNNLPSGKIAEIASLTVLMNDLDALMANRESIAEKLKNLCKKDDITLKLLSPQKDKSLIYAEEIQKYEPLQMSLNESFLKQQKLIEDIRKENEKFTNQKSKQGNQREEILQKYANAYKVYNELKANLDEGTQFYLNFQEILNKFLNRCKDFTTGRENEKIELKRQIEAGVNPHSPLTSPSPSLQSPVNNYPNQFSSPQYHTSPNQQQQQQQQYVPSSQPPPQYSYNPQPYQPPQQFGGPLPPPQSFSAPPPPQSFTAPPPYNSNNKHY
What is the function of this protein?
Unknown.  Required for development but not for cell death.
What are the official names of this protein?
ALG-2 interacting protein X, Alix, Dd-Alix, DdAlix.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle membrane. Endosome. Note=Colocalizes to large vesicle-like structures with chmp4. Colocalizes with vamp7A to endosomes but not to lysosomes.
Protein: SCXX_CENNO
Sequence: MNSLLMITACLVLFGTVWAKEGYLVNKSTGCKYGCFWLGKNEGCDKECKAKNQGGSYGYCYAFGCWCEGLPESTPTYPLPNKTCSKK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin CngtIII.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUSB_STRR6
Sequence: MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDTDVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFDTPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: KATG_POLAQ
Sequence: MTSKGMCPVAHGANTEASETPMAWWPKALNLDILHQQDTKTNPMGSSFSYRDELKKLDVGALKKDMKDLLTNSQDWWPADWGHYGGLMIRMAWHSAGSYRIADGRGGAGTGNQRFAPINSWPDNANLDKARRLLWPIKKKYGNKISWADLMILAGTIAYESMGLKTFGFSFGREDIWHPEKDIYWGSEKEWLQKSGGKGSRYSGERELSNPLAAVMMGLIYVNPEGVDGKPDPLKTAQDMRVTFARMAMNDEETVALTAGGHTVGKAHGNGNAANLGPAPEAAPIDEQGLGWMNHKTRGIGRDAVTSGLEGAWTTHPTQWDNGYFNLLLNYDWKLTESPAGAHQYEPINIKEEDKPVDVEDASIRCMPMMTDADIALKMDPEYRKISERFSKDQAYFSETFAKAWFKLTHRDMGPKARYFGPDVPKEELIWQDPIPSGPKSYDIDAVKAKIKASGLSMSDMVTTAWDSARTFRGSDKRGGANGARIRLAPQKDWMGNEPERLARVLAVYEKIGKECGISIADTIILGGNIGIEQAAKAGGFDVKVPFTSGRGDAIQAMTDVESFEVLEPLADGFRNWLKESYVVTPEELLLDRTQLMGLTAQEMTVLIGGMRVLGTNYGGSKQGVFTEKEGVLSNDFFVNLTDMNYLWKPTGQNSYDIVERNTEKTKWTATRADLVFGSNSILRAYAEVYAQDDNKEKFVNDFIAAWTKVMNADLFN
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RS13_CLOB1
Sequence: MARISGIDLPKEKRVEIGLTYIYGIGLPTSQEILKATGVNPDTRVKDLSEEEVNAIRDYVNKNVKVEGDLRREIKLNIKRLVEIGSYRGIRHRRNLPVRGQKTKTNARTRKGPKRAIGGKKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MURA_NEIG2
Sequence: MDKLKISANGPLNGEITVSGAKNAALPLMCAGLLTSGTLRLKNVPMLADVATTQKLLQGMGARVLTDNISEFEINGGTVNNTCAPYELVRTMRASILVLGPTLARFGEAQVSLPGGCAIGSRPVNQHLKGLEAMGAEIAIEHGYVKAKGKLKGARVAMDVVTVGGTENLLMAATLAEGTTVLENCAIEPEVVDLAECLVKMGAKISGIGTSTMIVEGAGELYGCEHSVVPDRIEAGTFLCAVAITGGRVVLRNAAPKTMEVVLDKLVEAGAVIEAGDDWIAIDMRQRPKAVDIRTVVHPGFPTDMQAQFMALNAVAEGSCRVVETIFENRFMHVPELNRMGANITTEGNTAFVQGVERLSGAVVKATDLRASASLVIAGLAARGETVVERIYHLDRGYENIEKKLGSVGANIERVSG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_GEOMG
Sequence: MEKRALIAVILSIVFFYGYSALFPPPKKEAPAPSAQQAVTGSQPGAPQASVAAVPAPSPVPAAAVKAQQKEIAVETPDYTAVFSTQGGSLTRLVLKKYRETADLTGKHVTLVDERDPSAYTLSTRAAGIGLDPSALFVSSADSLTVEAGEEKKELAFTWISPAGVTVRKIYTFQGGNYGIDMVYQTANSGTARVGAAFQTVMTYPAVPRVKESRLETFGPVTFAQDKLTEEKVKDLVGQGKSYSAPLWSGFADKYFLSAVVGQGGSIATAAVRSTPRGMLEDTITAPETSLNPGESKSVAYRLYFGPKDLDILKAQGNSLERAIDLGWFAMLAKPLLHSLKFFYKYVHNYGIAIIIITVILKIIFYPLTHSSYKSMKQMQKLQPKMQEVREKYKNDRDAMNKAIMELYQTHKVNPVGGCLPMLVQIPVFFALYKALMFSIELRHAPFMLWIQDLAGKDPYYVTPIIMGITMVIQQKMTPSQMDPMQQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQSYINKSIAAAEAK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPT_LEIAM
Sequence: MTLGLVESSRNAAFAVAAHAPVLGLILLGSIVAYVGTLRYIPNVARTLLDRNIFGIDINKSTEEQRQKFAAKRRAGQTEEKEFQKQAIPESLGILVGAMYLSVVVVLTVCLRFLGAAGEGLDNPYASLPGPLMTITVMLLLGFVDDVLDVKWRHKIILTALGSLPLIMTYDGSLSVLMPCAFGRFGLSTMNVMKEWRLGLAAPQGEPTTTFRATAPSTWFSFTVNHRSYVKVTESGAALIYLGPVYLVYLSMLCIFCTNSINILAGVNGVEVGQSIVIAVASVVYNLFQMRLDRQLTPDFSSLDAAAADARDMTSDHQLRALLLLGPFIGVSLALWRYNRYPARVFVGDSYTYFAGTVLAVSSITGVYSKTLLLFFAPQVFNFLISLPQLFSIVPCPRHRVPTWNPRTNLLSNSHNYTILNVILYLFGDMHEAKLTWAILKCQVIACVLGFVVRYVLSAFLYDEVR
What is the function of this protein?
Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
What are the official names of this protein?
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, GlcNAc-1-P transferase, G1PT, GPT, N-acetylglucosamine-1-phosphate transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SBOA_BACSU
Sequence: MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
What is the function of this protein?
Has bacteriocidal activity against some Gram-positive bacteria such as Listeria, some species of Bacillus and E. faecium (PubMed:10572140, PubMed:19633086, PubMed:3936839).  A single mutation (Thr-14-Ile) confers hemolytic activity against rabbit and human blood (PubMed:19633086).
What are the official names of this protein?
Subtilosin-A, Antilisterial bacteriocin subtilosin.
What is the protein family that this protein belongs to?
Belongs to the bacteriocin class V family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_MESFL
Sequence: MAITKEDIIKALEEMKLTELNELVKAIEEHFDVVASAGVAVAAGPAVADAAPSEVAIMLTNAGGQKVAVIKVVKEVTGLGLMDAKKLVDGTLPVAIKENVKIEEADAIKAQLIEAGASVEYK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PP2A_DROME
Sequence: MEDKATTKDLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAALMELDDSLKFSFLQFDPAPRRGEPHVTRRTPDYFL
What are the official names of this protein?
Serine/threonine-protein phosphatase PP2A, Protein microtubule star.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2A subfamily.
Protein: NPD_BACSU
Sequence: METFKSILHEAQRIVVLTGAGMSTESGIPDFRSAGGIWTEDASRMEAMSLDYFLSYPRLFWPKFKELFQMKMSGSFEPNEGHLLLAELEKQGKQVDIFTQNIDGLHKKAGSRHVYELHGSIQTAACPACGARYDLPHLLEREVPECTAAGNNGDICGTVLKTDVVLFGDAVMHFDTLYEKLDQADLLLVIGTSLEVAPARFVPEDASLIPGMKKVIINLEPTYCDSLFDMVIHQKIGEFARSLGMKK
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPE_SODGM
Sequence: MDQFATISMEQARERWRQGEAVLVDIRDPQSFAAGHLRGAFHLTNDTLPAFLAQHDLARPVMVLCYHGNSSKGAAQYLLTQGVEVAYSVDGGFDAWLKAFPLETESL
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OFUT1_HUMAN
Sequence: MGAAAWARPLSVSFLLLLLPLPGMPAGSWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKLLNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPEKRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQRFSPKEHPVLALPGAPAQFPVLEEHRPLQKYMVWSDEMVKTGEAQIHAHLVRPYVGIHLRIGSDWKNACAMLKDGTAGSHFMASPQCVGYSRSTAAPLTMTMCLPDLKEIQRAVKLWVRSLDAQSVYVATDSESYVPELQQLFKGKVKVVSLKPEVAQVDLYILGQADHFIGNCVSSFTAFVKRERDLQGRPSSFFGMDRPPKLRDEF
What is the function of this protein?
Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines.  Specifically uses GDP-fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer.  Plays a crucial role in NOTCH signaling.  Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that can then extend the fucosylation on the NOTCH EGF repeats.  This extended fucosylation is required for optimal ligand binding and canonical NOTCH signaling induced by DLL1 or JAGGED1.  Fucosylates AGRN and determines its ability to cluster acetylcholine receptors (AChRs).
What are the official names of this protein?
GDP-fucose protein O-fucosyltransferase 1, Peptide-O-fucosyltransferase 1, O-FucT-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 65 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: PPNP_LEPIN
Sequence: MSQFENVTIIKKANVYYDGKVTSRSILFQDGSKKTLGILMPGQYDFGTDEKEIMEILDGELLVKLPGQEVWSEIKGGQSFEVPAKSRFQMDVKKISDYCCSYIQNS
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: MRK1_YEAST
Sequence: MTDVLRSLVRKISFNNSDNLQLKHKTSIQSNTALEKKKRKPDTIKKVSDVQVHHTVPNFNNSSEYINDIENLIISKLIDGGKEGIAVDHIEHANISDSKTDGKVANKHENISSKLSKEKVEKMINFDYRYIKTKERTIHKRVYKHDRKTDVDRKNHGGTIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHVFPNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYFDETKRCDTDTYVKAQNLRIFDFDVETELGHVPLVERPAIEERLKHFVSAPSSSL
What are the official names of this protein?
Serine/threonine-protein kinase MRK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Protein: RHAT_ENT38
Sequence: MNHAITMGIFWHLIGAASAACFYAPFKKVKHWSWETMWSVGGTVSWLILPWTISAILLPDFWAYFTSFNASTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPILNGNFDVLINTHGGRMTLLGVLVAVIGVGIVTRAGQLKERKMGITAEDFNLRKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGALVNLGFCFIRLAKVKNLSVKADFSLAKPLIVTNVLLSALGGLMWYLQFFFYAWGHASIPSQYDYMSWMLHMSFYVLCGGMVGLVLKEWNNAGRRPVGVLSLGCVVIIIAANIVGLGMAS
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1075_BORPA
Sequence: MPARASRPAPGLPARAGLGFKPEHYATLVEQPPDLGFFEIHAENYMVPGGPAHAQLAWLRERYAISVHGVGLSLGGHDPLDARLLAGHRQLQRRYAPDSISEHLAWSRHDGRYFNDLLPIVYDDAALRRVCAHIDQFQQCLGQPILLENPATYVRFEASHIDEAQFLCELVARTGCGLLLDVNNVYVSAVNHGFDARAYLARLPLAAVGEIHLAGHARQRDAHGRAVLIDSHDAPVDEAVWDLYEYTLALTGPVATLLERDGNIPPLAALLAETGRVAACLARGLALAA
What are the official names of this protein?
UPF0276 protein BPP1075.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.
Protein: ST_POVBA
Sequence: MDKVLNREESMELMDLLGLERAAWGNLPLMRKAYLKKCKEFHPDKGGDEDKMKRMNTLYKKMEQDVKVAHQPDFGTWNSSEVCADFPLCPDTLYCKEWPICSKKPSVHCPCMLCQLRLRHLNRKFLRKEPLVWIDCYCIDCFTQWFGLDLTEETLQWWVQIIGETPFRDLKL
What is the function of this protein?
Promotes efficient viral genome replication by accelerating both G1 and S phase progression of the cell cycle.  Inhibits host PP2A by binding to the A subunit, thereby displacing lower affinity regulatory B subunit.  Inactivation of PP2A in turn results in the transactivation of cyclin A and cyclin D1 promoters.  Late during the infection cycle, ST may induce dephosphorylation of host MTOR, leading to the inhibition of cap-dependent translation.  May establish and maintain high levels of viral genomes during persistent infection in cell culture.
What are the official names of this protein?
Small t antigen, ST, ST-AG.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: YK213_PLAF7
Sequence: MNKFFQILEYFKIELSINFSITFIFINILLVFFSTFLYRNIKKVNDPDSYKTSYERKEKDSTFDEEENFDILNIFSNDPKSVENIYELENDIYNKSEESSICSNHNKNLDEKTYKINKKKVTIYLKLNEGLENIKQELHIIDRELKNILQKEENLQLINEEENIIIEKTKSDKYDEKENKSNDNILSKKHDDENINKSDIRNTLDSELKKKYELCKENNQLLENHHNNDNNQEDNNICEIEKQDYNNYNSDNKNHNDIFNYNYEDISLEKDKNIHHTKEITKNDTLCNTLDSIKNNRPTEEKTKNFNYNETNIYEENKKLKDSIVNSKNGENFLLKNNEQNINNNIINVNQKQSSDHKKESFKIDTKKNDQIEQNYQNGKNEKNEENEKNGMNEQNGKNEQNGKNEQNGKNEQNEQNDQIEQNYQNDPNDQNDQNDQNEKNDQNEKNDQNKKNEQNIGPKKTNEISYDSININISNNQNPKLSNVFVEDIKRILPISNNNLENSITTIKNIDDPSNSTKQELQNSDYENMHANKKIENGKESFICDITSNTNITRNSMDIPNIMDRKKSEYDKEVDNVSIKKKSYINHNMQRENTREDPSNNMDYTNKSTSDSNDIENENKMERCTNILGLDKRETVIKINDINKDNKHTNGIKCEDKRKSTSIHMEDINNSTNYLNNKEYNSKGENNNNILGDDKRESTFKIYDIQKSEYNSNDLQYDNKRERTSINLDNGNKNNVDINNYINVDDTKERISINLDNVNKNNVDINNYINDDNTKERTSINLDNGNKNNVDINNYINDDNTKERTSINLDNGNKNNVDINNYINDDNTKERTSINLDNGNKNNVDINNYINVDNTKERTSINLDNGNKKNVDINNYINDDNTKERTSINLDNGNKNNVDINNCINVEDKRERYSHILNINKRESIIKINDMKKTKSDSNDIKINDNRTEMYSNIFEINEKERTSIKVDTVKENKSDSNDIENGNKIERHSNVLYINPTKFDPIKINDINKKGERYYDNIENEDKREIYTNNDEYMDKRESNTNHIYINKKESYLENAKDVIKKESPLNNVEDTKKEESYSKNIENANKEEYESNEETYVNKMEEDSNDIEDISNRKYEYKEGQYLNKGEKYINNIDNVSIKESYYNKREKESIEISNLNKRESCTSNINNFRIRENQSNMVEYENKRKSDNIEINNLNKADIYVNSIKNVSKRNSSYNKKERDSKKDRDSVYDENRRKSSAYQINDIYNIRDKSKEKIDMDTIQDMNKRKSYVDNIHITNKKYSDINNAEDVIREKKYEDYNISVMYNMHNKRDQRKESNINIYNDNNMRRSTINKINDENSMHNVKNEIKNIDNNNNVDKINVNKSNTDKIYMDKIYMDKIYMDKRYMDKRYMDKRYMNKRYMDKIYMDKIYMDKIYMDKIYMDNEYMTDNIIKKNDKYNNNNNNNNSDVVEYVNERKHTSLINEHYLYERKSNVDKMKDINKGENDILYDVYNNSEKKNTKSSLYRNPEIITQGGNDNINNMNEHISSLNKVYRISNKKSNNNYKGQDYTYIVNENSGRNSSMYNNINNSDNMNKKECDFINDKENINKRISEIYDLRQINHNESNIENMENIKNMENIKNMENIKNMENIEHIKNMENMEHIKNIQNIEHIKNIENIQNIQNMEHIKNIESIQNIQNMEHIQNIENIQNIENIQNIENIKTIENIKKNIENINNKGSLMVNSNNINENIKKESDIYKIECDDDHMCDVTKIKGVDKQMSDTHKIKYDDNEKNNENKRKSGINKVFDIIKRTMDSYNIYNLSKCKIDEDNIYMLNEKKKNNINNMNKRKSENTYNINEREKDDMNRRMTENTYNLNKEKNLSVHNIKNIQPYNINNNIYEKTNDTIDNLNETGKNNTNDISIKGSDKNKEYKFYDNENKDNINMIIRDTINMSNLNNNISDNMQMAIHKEEKNIHKMNRKITYTNNLYNINESKTEYTININEQEEKSDFINNDNIKMDNEDKLYNCNERNNHIHKENKRNDIKYDNFKKDNIRKNMDNTKNIENMNNIDNMDNTKHIENVNNMKNIENVNNINNIDNMDNKKHIENVNNMKNIENVNNINNIDNMDNKKHIENINNMKNMENMNNINNIENMNNMKNIENMNNMKNIENMNNINNIENINNMKNIQNINNIENMDNMNNTKYIENMDNMNNIENMNNINNYNKIYDVNIINNKNYDSTYNELYEKDNQEENKNICNDKLDNSINEKTKYMKTLREYFVKSEKEIEDQKKNNMNDMYTRREEEKIKDNEDWKLYDFKNLKEKYKFQMNMKDSEINQLQNNLIDEFKELNEVSKLKNNLKGKTYNSNIGEEMLEENKEKQHGNYVGEYFDRNDMILKERIFEYAKHKTSIDMLKHPDDIKRNSKDLKKWKSQVITKKYADDWLSSDVLLSCFLNFIKLKKYVNITELSVKFQTTTDDIREKLEELEEQDMINGVLDEKGNYIYLSQEEINKLCFEIQSKGKVNTHDDFVKICNKVISLSVNDKDMEKLKEEEEKIIKAKTEIF
What are the official names of this protein?
Uncharacterized protein PF3D7_1120600.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VATF_HALS3
Sequence: MSQEIAVIGSPAFTTGFQLAGVRKVENVADDEKDDDLDAAVEAVLADEDVGIAVMHDDDLAHLSRGVRQSVEASVEPTFVTIGGGASGASGLRDQIKRAIGIDLMDDDDDASAADTEAGD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: ACCA_ECO24
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHXH_SCHPO
Sequence: MLTVECLIYAINFTSDSIGRSLKLWGTSRRLRFAETESFHNKKPTSLFTQHEFSYSCAYQ
What are the official names of this protein?
Putative uncharacterized protein C3E7.17.
Protein: Y2969_YERPA
Sequence: MNNPDDVLLINRFLRQQHVLTLCAGSGMDMWCASCFYVFDENQMALFLMTEKHTRHSELMLINPQVAGTVATQSRTIALIKGIQYRGEISLLSGDAEQAARNRYCRRFPVAKVSSAPLWQLNLLEIKMTNNALGFGKKLHWSRVEPL
What are the official names of this protein?
UPF0306 protein YPA_2969.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: HDCB_LACS3
Sequence: MSNSNYQVSLERIKKVVPEELLTNALLAAIDNSGERMSQIIVDKKDNGNDYYLTIHRFFVYSNEEFTAFDKEDVADVEFVNGTPDGEVIITLKDGKVLHPSHICYGRAFDFIQDVKPKVITMAGYDSTIRGEFPQLLDPDHAEEIDRLRRWMQDGNISHYEYDDANPAYPKAGK
What are the official names of this protein?
Protein HdcB.
Protein: VF546_SPTNK
Sequence: MSNMYCGIGKVPKGKERGTPEHCFQSNQIRYYGIKKIDKSLLEKPKKKRLSLIKEQTKLNNLLEKGKRMVKEANKLKSIINDPESSKTEIRNAKKKLEKIVAKKNKFVLELKQQRQVVDELLEEEREKEKAERKAEKAKKNKKKSSTKTKKK
What are the official names of this protein?
Uncharacterized protein V12.
What is the protein family that this protein belongs to?
Belongs to the mimivirus R546 family.
Protein: A7L3B_HUMAN
Sequence: MEEISLANLDTNKLEAIAQEIYVDLIEDSCLGFCFEVHRAVKCGYFYLEFAETGSVKDFGIQPVEDKGACRLPLCSLPGEPGNGPDQQLQRSPPEFQ
What is the function of this protein?
By binding to ENY2, interferes with the nuclear functions of the deubiquitinase (DUB) module of the SAGA complex which consists of ENY2, ATXN7, ATXN7L3 and the histone deubiquitinating component USP22.  Affects USP22 DUB activity toward histones indirectly by changing the subcellular distribution of ENY2 and altering ENY2 availability for ATXN7L3 interaction.  Regulates H2B monoubiquitination (H2Bub1) levels through cytoplasmic sequestration of ENY2 resulting in loss of nuclear ENY2-ATXN7L3 association which destabilizes ATXN7L3.  Affects protein expression levels of ENY2 and ATXN7L3.
What are the official names of this protein?
Ataxin-7-like protein 3B.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Cytoplasm.