PharMolix/UniProtQA huggingface dataset:
Protein: ECFA_METTH
Sequence: MIELRDLSYSYPDGTPALRGINMKVERGERVAVIGPNGAGKSTLFLHLNGILKPAAGEVIIDGERVDYSKDELIKIRQKVGIVFQNPDDQLFSPTVREDVAFGPMNLGLPEDEVEERVAESLEKVGMSGYENRAPHHLSGGEKKRVAIAGILAMKPEIMVLDEPTTGLDPETADGIIRILLELSREGITVMISSHDVEIISQFAERVFVLNSGELIAEGTPLEIFRDAELIRRASLRLPRTADLLNRLRMAGFEVDVKLTVEETYHELLHLLGGDAYHRLLHFLGEEKQHRLIHLLGEKKYHELLHALKEQ
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA, ECF transporter A component EcfA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CHS6_YEAST
Sequence: MNLFWPSETKKQNEIPGGDYTPGNSPSVQKGYQFLNRDIFKSCPRIMERQFGECLHNRTHLIKDLISSGNVGLGPIEIVHMSYLNKHEKEEFGEYFYVTGIEVSGPAMPVEFLEVLKSSKRISKNISNNIILTYCCFNFFSNLDIRIRYDADDTFQTTAIDCNKETTDLTMTEKMWEETFASSVIRAIITNTNPELKPPGLVECPFYVGKDTISSCKKIIELLCRFLPRSLNCGWDSTKSMQATIVNNYLMYSLKSFIAITPSLVDFTIDYLKGLTKKDPIHDIYYKTAMITILDHIETKELDMITILNETLDPLLSLLNDLPPRDADSARLMNCMSDLLNIQTNFLLNRGDYELALGVSNTSTELALDSFESWYNLARCHIKKEEYEKALFAINSMPRLRKNDGHLETMYSRFLTSNYYKKPLNGTREHYDLTAMEFTNLSGTLRNWKEDELKRQIFGRIAMINEKKIGYTKEIWDDIAIKLGPICGPQSVNLINYVSPQEVKNIKNINLIARNTIGKQLGWFSGKIYGLLMEIVNKIGWNGLLNIRTEAFMMETEFYQASNNIIDENGHIPMESRKKRFCEGWLDDLFLDLYQDLKLSKISLSNKDEKHSGLEWELLGLIMLRTWHWEDAVACLRTSIVARFDPVSCQQLLKIYLQPPKNIQEVTLLDTDTIISLLIKKISYDCRYYNYCQIFNLQLLEKLCNELGTHILRNKILLQPSIGDEIMVMIDAMLAWIADLDHTVQP
What is the function of this protein?
Member of the CHS5-ARF1P-binding proteins (CHAPS) which mediates export of specific cargo proteins, including chitin synthase CHS3.
What are the official names of this protein?
Chitin biosynthesis protein CHS6, Protein CSD3.
What is the protein family that this protein belongs to?
Belongs to the CHAPS family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Trans-Golgi network location requires interaction with CHS5 and with myristoylated GTP-bound ARF1 for the recruitment to the membranes.
Protein: RIMP_SALEP
Sequence: MGLSTLEQKLTEMITAPVEALGYELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPISVAYNLEVSSPGLDRPMFTADHYARFQGEEVALVLRMAVQNRRKWQGIIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MX_PERFL
Sequence: ITMNTLNQQYEEKVRPCIDLIDSLRSLGVEKDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLELKMKRRQEGEEWYGKISYQDCEKEIEDPADVEKKIRDAQDEMAGVGVGISDDLISLEIASPDVPDLTLIDLPGIARVAVKGQPENIGDQIKRLIQKFIKRQETISLVVVPCNVDIATTEALKMAQEVDPDGERTLGILTKPDLVDKGTEETVVDIVHNEVIPLKKGYMIVRCRGQKDITDKVSLTEAIEREKAFFNDHVHFQTLYNDGHATVPKLAEKLTLELVHHIE
What are the official names of this protein?
Interferon-induced GTP-binding protein Mx, Interferon-inducible Mx protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_BRUMB
Sequence: MSIDSLPPLREVIERHDLMPKKSLGQNFLFDLNLTSKIARQAGDLRDQPVIEVGPGPGGLTRALLAQGAYVTAIERDDRCLEALAEIAAHYPGRLRIIAGDALEQDFTALFPEGPKPRIVANLPYNVGTQLLLNWLLVEPWPPFYSSMTLMFQREVAERIVAKPDSDHYGRLGVLAGWRTQAKIAFDVPPQAFTPPPKVMSSVVHIVPRETPLPCRAEALGQITQAAFGQRRKMLRQSLKSIGGAALLEKTGIDGTRRAETLSVEEFVALANACLP
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y806_METJA
Sequence: MQKTIGDIMNNRIERFLKYMESEGIKKAVILKKENINYFLGKYFMSFSVLVFEEQPYLYVGKLDKDYAEEHFNFLEIREFKSWEEIFKGCDGVEKELSIGYLKYIDKEYKIISDKIKEMRMIKDKEEIKLIKKAAEISDKAINWVLNNLDEVKNLTEYELVAEIEYIMKKHGSIKPAFDSIVVSGKKTSFPHALPTKDKIADILLVDIGAVYEGYCSDITRTFLLKDDEEMKKIYNLVYEAKKVAEEHLKEGISAKQIDNIVREFFNDYKELFIHSLGHGVGLEVHEEPRLSNKLKDDEDIILKEGMVVTIEPGLYLKDKFGVRIEDLYLVKKNGFEKLSKAEISEY
What are the official names of this protein?
Uncharacterized peptidase MJ0806.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: TSAD_GLOVI
Sequence: MTTIFAIETSCDESAAAIVRGRTVVASIIASQIDVHRLTGGVVPEVASREHLQALGGVIAACFAEGGLGWADIDAVAFTCAPGLVGSLLMGSMAAKTLALVHARPLVGIHHLEGHIYSAFLSDPALEPPFLCLLVSGGHTSLVAVEDHGRYRILGRTRDDAVGEAYDKVARVLGLGYPGGPAIDKLAQRGDPRAFALPGGRVESPFDTSFSGLKTAVLRLAEKHRLQRLPIDRADLAASFQRTVVETLAERVELALAHTGYDTVVVAGGVSANRGLRERLGQAGPYRAVFPPMHFCTDNAAMIACAGVARFERGFRSSLDLPVQSRLSLEACDSLYQCLPVP
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FENR_RHOP2
Sequence: MTETIKTDVLIVGAGPCGLFAVFELGLLDIKTHLVDILDKVGGQCAELYPEKPIYDIPGVPMITGHGLTEALMEQIKPFNPTIHLNEMIESVEKIGDPEFRVTTNAGTVFECKVLVVAAGGGSFQPKRPPVPGVEAYEGKSVHYAVRKMEEFRGKDIVIVGGGDSALDWTLNLNPICKSMTLVHRRDDFRGAPHSVEQMRQLVASGKLDLKIGQITELQGEDGQLSGATIKLNGNSIAQIKCDAMLPFFGLTMKLGPVANWGLQLENNLIPVDTGTFETNVPGIFAIGDINTYPGKLKLILSGFHEGALMAQKAVKYVYPDKRVVFQYTTSSTNLQKKLGVN
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: PT309_YEAST
Sequence: MKRCAPAVLRNYNYKKGIWSTGVPDHIRKLLRDKSTSPLCSQDERNLVSYFMARGSVPLKSVGSGLTKKATTSITSNSATTTFERQYLIKYLYRHQAYGNVIKIAQKFLYTTIGSQRLLKQDASLPELKKFLLSLLILQRGIQLDQAISDIIQRFLLTQKTMVIDLINSIFSRMVIMNMHEEAVYKWVKWMKLVNGHCEFTNYMENKIVLRNFLSFMRQSNVRPDYLSYLKAIQLTQGPAIASQFATTLLFLLTYIRKFSSAEAVWNYKCEHNLPIVSSDLTCILKTYCHMQKFNLVSSTYWKYPDAQHDQNQFDYLLVAHSRLHNWDALQQQFNALFGIGKLPSIQHYGILMYTMARIGELDSVNKLYTQLLRRGMIPTYAVLQSLLYAHYKVGDFAACFSHFELFKKYDITPSTATHTIMLKVYRGLNDLDGAFRILKRLSEDPSVEITEGHFALLIQMCCKTTNHLIAQELFNLMTEHYNIQHTGKSISALMDVYIESNRPTEAIALFEKHSKNLSWRDGLISVYNKAIKAYIGLRNANKCEELFDKITTSKLAVNSEFYKMMIKFLVTLNEDCETALSIIDQLIKHSVIKVDATHFEIIMEAYDKEGYRDGIINLYKTMSQNKVPANSKILYYILKAVAKKSLQNNEEIKETINMVEDIMENAANGTLDVTYNKLHPSVMAWPMRMIVKHDSPQRALELYNRYNELFFKKHDWISNNNKFVMMRSLLVLLAQIEQWKDFETLFAKYMDRIENIENLPSSTTPNIKLRSIFSGLFPYKVSQLIAMNKIDELPLLWKKLREKGFILDNISWNSAVEALFKDPRTLSYGMKIVDDTLIHGYNLIHKFRLLTKLSEDKTQSSDKSWPTLKMKEKEPNKFQPRLYLKSDTYNSIMRQLDTYLDGIDDLKTLEDQVRDFISNYKYFMKDYLLMPRSKINKWEQIEMRHLSYFKELRKSKRVLPVSKF
What is the function of this protein?
Required for initiation of translation of the COX1 coding region.  Also involved in the stability of the intron containing transcript of COX1.
What are the official names of this protein?
Pentatricopeptide repeat-containing protein PET309, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NIS1_YEAS7
Sequence: METYETSIGTQSYPPTLFPPPLGTGGFTTSGYIHALVDSTSNSNSNSNSNSNTNSNTNSNSDTKIPIVQISDDSHITHDSFKPYMEYHDASHLRNRNISKADQVDSTEVMEQFTQWSNYKMRSRSPTINAKPIRHTSQRRTDFTSKNELSKFSKNHNFIFHKGFLKRQHSIRREDRQAKVRSRFRSKKELTSVLNYIELEQMDIANVLASQSVNLHAIRNLTSRDPAVTPIPFLRSQMYATSSRPPYLRNRSIRRKLPKSQPGSLPTTTPATATKTIKQNSTTPTTRSVYNKNVGRSNTSPSVLYHPKRRGKLNTKSHARKEQLLLELWREYLMLVITQRTQLRLTLLCSPGSASNESSVCSSNASDLDMSLLSTPSSLFQMAGETKSNPIIIPDSQDDSILSSDPF
What is the function of this protein?
May be involved in a mitotic signaling network.  Binds sumoylated proteins and may stabilize SUMO chains (By similarity).
What are the official names of this protein?
Protein NIS1, Jumonji domain interacting protein 1, Neck protein interacting with septins protein 1.
What are the subcellular locations of this protein?
Bud neck. Cytoplasm, cell cortex.
Protein: ISPD_SYNSC
Sequence: MHLLIAAAGSGRRMGADRNKLLLPLAGRPVIAWTIEAALRSERIEWIGIVGQEVDREAILAVLDEPSKPVHWIQGGSTRQESVLCGLAGLPEQARHVLIHDGARCLAEPKLFDRCAAVVEDGTALIAATPVSDTIKRVGSDGVIRDTPDRSELWAAQTPQGFAVDQLRRGHAEAVAQGWTVTDDASLYERLGWPVQVLDAGPANIKVTTPFDLTVAEAVLALRSAG
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: IFNAF_BOVIN
Sequence: MAPAWSLLLALLLLSCNAICSLGCHLPHIHSLANRRVLMLLQQLRRVSPSSCLQDRNDFALPQEALGGSQLQKAQAISVLHEVTQHTSQLFSTEGFGAVWDESLLDKLRAALDQQLTDLQACLRQEEGLRGAPLVKKDSSLAVRKYFHRLTLYLQEKRHSPCAWEVVRAEVMRAFSSSTNLQESFRRKD
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-F, IFN-alpha6.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: SECB_SPHAL
Sequence: MADETSADINNPALQPNGEDTSPAIGLISQYVKDLSFENPNAPAVYQWQGAPQVDVQFNIAADSVGDNLYEVLLKIDVTSKTDKGTSFVIELKYAGLFGVRNVPDDQLQPFFLAEAPRILFPFARRVVADAVQDGGFPALLLEPIDFHGLFMQQVQAAQGEQVGDGAPVGQA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_WHEAT
Sequence: MALSVEKTSSGREYKVKDLFQADFGRLELELAEVEMPGLMACRTEFGPSQPFKGARISGSLHMTIQTAVLIETLTALGAEVRWCSCNIFSSQDHAAAAIARDSAAVFAWKGETLEEYWWCTERCLDWGVGGGPDLIVDDGGDATLLIHEGVKAEEEFEKSGKVPDPESTDNPEFKIVLTIIRDGLKTDASKYRKMKERLVGVSEETTTGVKRLYQMQESGTLLFPAINVNDSVTKSKFDNLYGCRHSLPDGLMRATDVMIAGKVAVVCGYGDVGKGCAAALKQAGARVIVTEIDPICALQALMEGIQILTLEDVVSEADIFVTTTGNKDIIMVDHMRKMKNNAIVCNIGHFDNEIDMNGLETYPGVKRITIKPQTDRWVFPETKTGIIVLAEGRLMNLGCATGHPSFVMSCSFTNQVIAQLELWNEKASGKYEKKVYVLPKHLDEKVAALHLGKLGARLTKLTKSQSDYISIPIEGPYKLRLYRY
What is the function of this protein?
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
Protein: RL2_STRT2
Sequence: MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRNNNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKAYIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVIHNIELKPGKGAELVRAAGASAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLINLGKAGRNRWKGVRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNEK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: MTRB_MYCPA
Sequence: MMWGSRRRTRSRWGRSGPMTRGMGAVSRAVGTAWRRSLQLRVVALTLGLSLAVILALGFVLTSQVTNRVLDVKVKAAIEQIERARTTVGGIVNGEEARSLDSSLQLARNTLTSKTDSASGAGTAGTFDAVLMVPGDGPRAATTAGPVDQVPASLRGFVKAGQASYQYATVHTDGFSGPALIVGSPASSQVANLELYLIFPLKNEQATIQLVRGTMITGGAVLLVLLAGIALLVSRQVVVPVRSASRIAERFAEGHLSERMPVRGEDDMARLAMSFNDMAESLSRQITQLEEFGNLQRRFTSDVSHELRTPLTTVRMAADLIYDHSADLDPTLARSTELMVNELDRFESLLNDLLEISRHDAGVAELSVEAVDLRSTVQSALSNVGHLAEDAGIELQVELPAEEVIAEVDTRRVERILRNLIANAIDHAEHKPVKIRMAADEDTVAVTVRDYGVGLRPGEEKLVFSRFWRADPSRVRRSGGTGLGLAISIEDARLHQGRLEAWGEPGVGSCFRLTLPLVRGHKVTTSPLPMKPIPQPSPSGGQSPSTGPQHAKDRARQREHAERSL
What is the function of this protein?
Member of the two-component regulatory system MtrA/MtrB.  Seems to function as a membrane-associated protein kinase that phosphorylates MtrA in response to environmental signals (By similarity).
What are the official names of this protein?
Sensor histidine kinase MtrB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CML49_ARATH
Sequence: MSGYPPSSQGYGYGGNPPPPQPPYGSTGNNPPPYGSSGSNPPPPYGSSASSPYAVPYGAQPAPYGAPPSAPYASLPGDHNKPHKEKPHGASYGSPSPGGYGAHPSSGPSDYGGYGGAPQQSGHGGGYGGAPQQSGHGGGYGAPPPQASYGSPFASLVPSAFPPGTDPNIVACFQAADRDNSGFIDDKELQGALSSYNQSFSIRTVHLLMYLFTNSNVRKIGPKEFTSLFFSLQNWRSIFERFDKDRSGRIDTNELRDALMSLGFSVSPVILDLLVSKFDKSGGRNRAIEYDNFIECCLTVKGLTEKFKEKDTALSGSAIFNYENFMLTVLPFLVA
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML49, Calmodulin-like protein 49.
Protein: SL9A3_MOUSE
Sequence: MWHRALGPGWKLLLALALTSLQGARGAEEEPSSDGSFQVVTFKWHHVQDPYIIALWILVASLAKIVFHLSHKVTSIVPESALLIVLGLVLGGIVWAADHIASFTLTPTLFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVIGTIWNAATTGLSLYGVFLSGLMGELKIGLLDFLLFGSLIAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVTLGGDAVTGVDCVKGIVSFFVVSLGGTLVGVIFAFLLSLVTRFTKHVRIIEPGFVFVISYLSYLTSEMLSLSSILAITFCGICCQKYVKANISEQSATTVRYTMKMLASGAETIIFMFLGISAVNPDIWTWNTAFVLLTLVFISVYRAIGVVLQTWILNRYRMVQLETIDQVVMSYGGLRGAVAYALVVLLDEKKVKEKNLFVSTTLIVVFFTVIFQGLTIKPLVQWLKVKRSEHREPKLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSNFDRKFLSKVLMRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNMVNVDFNTPRPSTVEASVSYFLRENVSAVCLDMQSLEQRRRSIRDTEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPNEDEKQDKEIFHRTMRKRLESFKSAKLGINQNKKAAKLYKRERAQKRRNSSIPNGKLPMENLAHNYTIKEKDLELSEHEEATNYEEISGGIEFLASVTQDVASDSGAGIDNPVFSPDEDLDPSILSRVPPWLSPGETVVPSQRARVQIPNSPSNFRRLTPFRLSNKSVDSFLQADGHEEQLQPAAPESTHM
What is the function of this protein?
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions.  Major proton extruding system driven by the inward sodium ion chemical gradient.  Plays an important role in signal transduction.
What are the official names of this protein?
Sodium/hydrogen exchanger 3.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi- pass membrane protein. Note=In intestinal epithelial cells, localizes to the ileal brush border. Phosphorylation at Ser-663 by SGK1 is associated with increased abundance at the cell membrane. Angiotensin-2 enhances apical expression (By similarity).
Protein: MGSA_VIBPA
Sequence: MQKTTRTMPAHKHVALVAHDNCKPELLRWVKENKEKLQRHFLYATGTTGHMLSKETGLAIKSMISGPMGGDQQLGALISEGKIDVLVFFWDPLNAVPHDPDVKALLRIASVWNIPVATNRATAKFLFDSPLLEQEVDIEVPDYEAYLAERM
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: ADH_DROMY
Sequence: MVIANKNIIFVAGLGGIGFDTSREIVKSGPKNLVILDRIENPAAIAELKALNPKVIVTFYPYDVTVPVAETTKLLKIIFDKLKTVDLLINGAGILDDYQIERTIAVNFTGTVNTTTAIMSFWDKRKGGPGGVIANICSVTGFNAIYQVPVYSASKAAALSFTNSLAKLAPITGVTAYSINPGITKTTLVHKFNSWLDVEPRVAELLLEHPTQTTLQCAQNFVKAIEANQNGAIWKLDLGRLEAIEWTKHWDSHI
What are the official names of this protein?
Alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RM49_PONAB
Sequence: MAATMFRATLRGWRTGVQRGCGLRLLSHTQGPPDYPSFVESVDEYQFVERLLPATRIPDPPKHEHYPTPSGWQPPRDPPPNLPYFVRRSRMHNIPVYKDITHGNRQMTVIRKVEGDIWALQKDVEDFLSPLLGKTPVTQVNEVTGTLRIKGYFDQELKAWLLEKGF
What are the official names of this protein?
39S ribosomal protein L49, mitochondrial, L49mt, MRP-L49.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL49 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PRMB_NEIMB
Sequence: MVHIMFNQAAQELTTIRDILRFAVSRFNEAGLFFGHGTDNAHDEAAYLILHTLNLPLDMLAPYLDAKLLEAEKEEVLAVIERRAVEHIPAAYLTHQAWQGEFDFYVDERVIIPRSFIYELLGDGLRPWIEYDELVHNALDLCTGSGCLAIQMAHHYPDAQIDAVDVSLDALEVAGINVEDYGLEERIRLIHTDLFEGLEGTYDLIVSNPPYVDAESVELLPEEYLHEPELALGSGADGLDATRQILLNAAKFLNPKGVLLVEIGHNRDVLEAAYPELPFTWLETSGGDGFVFLLTREQLLGEE
What is the function of this protein?
Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.
What are the official names of this protein?
50S ribosomal protein L3 glutamine methyltransferase, L3 MTase, N5-glutamine methyltransferase PrmB.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
Protein: LRRF1_HUMAN
Sequence: MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKEDCTMS
What is the function of this protein?
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA.  May control smooth muscle cells proliferation following artery injury through PDGFA repression.  May also bind double-stranded RNA.  Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
What are the official names of this protein?
Leucine-rich repeat flightless-interacting protein 1, LRR FLII-interacting protein 1, GC-binding factor 2, TAR RNA-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the LRRFIP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RT07_RECAM
Sequence: MSRKKRIYKKNTNILQEPVFNDNVLLKFINCLMFDGKKSVAEKLVYNSFREIRKETSVDPIIVFNDAIRNTTPVVQVKSIRIAGSNYQVPMEIPTHRQIMLAIKWIIESARKRTEKTMVERLSKELIDAYKNSGKAIDKKISMHKMAESNRAYAHYRWQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to the small rRNA where it nucleates assembly of the head domain of the small subunit.
What are the official names of this protein?
Ribosomal protein S7, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MURB_LIMRJ
Sequence: MANLMNEFPDIEIKQDEPLMNYTYTKTGGPADWLAFPETIDQVKELVDYVREHEMGLTVLGNASNLIVGDGGIDDLTIILTRLNKIEVHDNKVTAQAGASYIATTEAARDSELTGLEFAAGIPGSIGGAVFMNAGAYGGETKNVVSEATVMLPDGTIKHLTNEELDFGYRHSSIQDNNGVVLDATFALEPGKYDEIKARMDDLNERREAKQPLDLPSCGSVFKRPEGYYAGKLIHDAGLQGYTSGGAQVSTKHAGFIVNIDHGTAADYVNVIHHVQKTVKEKFGVDLETEVRIIGRQD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPI2_SCOJE
Sequence: QMTCRISGEVFTWCGTTCPLTCENFRNPPKHCPQGCFVGCMCRRGLVRHRNGRCVRPPRCYY
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Venom peptide SjAPI-2, Ascaris-type protease inhibitor-2.
What is the protein family that this protein belongs to?
Belongs to the serine protease inhibitor-like (TIL domain-containing) family.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPP_PROM1
Sequence: MPEEISQYLFICFKSFFLGIIQGFTEFLPISSTAHLKVVPYLFGWNDLGVSFSASIQLGSAVAIIYYFRNQISLIINSFFSSFNPSKGFKDENSRLFIYIFVASIPILVFGLLIKLYWPNYSDSNLRGLFSIAITSIVMSLLLALSEIYGKRNKLFVDINLNDVIKLGLAQSLALFPGVSRSGITLTSALFSGIERKTAARLSFLVGIPAVSISGLVELFSLFRVLSVIDIIPIIIGIISSFFSSIFAIDLFLKFLSKNNTLVFVYYRLAFGIFILTTL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMI_COPPD
Sequence: MIYLVGTPLGNLEDITLRAIRVLGEADVVACESKERALKLLSHLQIKKPLIYLREASRASDVKRIIELHKQGKTVAVTTDAGMPGISDPGAYLVRELSAQGIPFTVVPGPSALCMSITVSGLEEPWAFLGFLPLKEGKRRRELEKFLPLNIGLVIYEGPHRVGKLLSLLNELCPQRKVALLRELTKLHEEVQVGYPHELIKDSYKGEFVVVVYPSQEGT
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP36_TRIVH
Sequence: MALSGILSKRVIAHRADENELEDDFSSSEELNTLGSEDDEDEDEDEDEGEGEGDESENEEAPDNASSEDDGDNDIKSSLSQISFGALAKAQQSLGPLKKGAKRKHGSEEEEEEDNKNTKYKKSKSDALNELRERIRRAKEEKASKSEGSRDNELLDKKHKEARSSKHAPAVQSSKYAVSRRRVVVDGENVAQVKSRDPRFDSAVQSYSHNAKSSSYATSHSDLAAAKNYAFLNEYRDAELKELEEKLRRSKKDDEKARLKKMITSMKDRKRAMENRERERQVLAKHRKKERELIKEGKKEKAWFLKKADLKKEALKEKYESMGAKERQKGIERRRKKVASKEKKEMPRSRRMVEG
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.