PharMolix/UniProtQA huggingface dataset:
Protein: GLO2_MOUSE
Sequence: MVLGRGSLCLRSLSALGATCARRGLGQALLGLSLCHSDFRKNLTVQQDIMKVELLPALTDNYMYLIIDEDTQEAAIVDPVQPQKVIEAAKKHHVKLTTVLTTHHHWDHAGGNEKLVKLEPGLKVYGGDDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPGSSEPSAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLGRLPPDTKVYCGHEYTVNNLKFARHVEPGNAAIQEKLAWAKEKYAIGEPTVPSTLAEEFTYNPFMRVKEKTVQQHAGETDPVTTMRAIRREKDQFKVPRD
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, mitochondrial, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion matrix. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: CDS1_MYCTU
Sequence: MSGGACIAVRSLSRSWTDNAIRLIEADARRSADTHLLRYPLPAAWCTDVDVELYLKDETTHITGSLKHRLARSLFLYALCNGWINENTTVVEASSGSTAVSEAYFAALLGLPFIAVMPAATSASKIALIESQGGRCHFVQNSSQVYAEAERVAKETGGHYLDQFTNAERATDWRGNNNIAESIYVQMREEKHPTPEWIVVGAGTGGTSATIGRYIRYRRHATRLCVVDPENSAFFPAYSEGRYDIVMPTSSRIEGIGRPRVEPSFLPGVVDRMVAVPDAASIAAARHVSAVLGRRVGPSTGTNLWGAFGLLAEMVKQGRSGSVVTLLADSGDRYADTYFSDEWVSAQGLDPAGPAAALVEFERSCRWT
What is the function of this protein?
A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S.  The H(2)S produced by this enzyme stimulates respiration in M. tuberculosis, mediated primarily via cytochrome bd with a lesser contribution from cytochrome bc1/aa3.  H(2)S modulates the balance between respiration and glycolysis, and also contributes to redox homeostasis.  Probably eliminates toxic levels of Cys (which can induce oxidative stress).
What are the official names of this protein?
L-cysteine desulfhydrase Cds1.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.
Protein: TATA_ALKMQ
Sequence: MFGKLGMPELVLIFAVALVIFGPSKLPEIGKSLGKSIKEFKKFSKEMKDDLSLEERETKDKDTVKVKEE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RUVC_HAES1
Sequence: MSIILGIDPGSRVTGYGVVRQVGHKLEYLGSGVIRTSIDDLPTRLKRIYAGITEIITQFNPNEFAIEQVFMAKNPDSALKLGQARGTAIVAAVNQNLPVFEYSPRTIKQTVVGTGAAEKSQVQEMVVRLLQLSDKPQVDAADALAIAITHANSIHNSLQIANSIAIKTPDKITALLRTKYRRGRLRLKG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ITB8_RABIT
Sequence: MCGSALGLPPAAFVRLRSCRPGPAAFLRAAWVLSLVLGLGRSENSRCASSHAVSCSECLALGPDCGWCVHEDFISGGPRSERCDIVSNLISKGCPVDSIEYPSVHVTIPSENEVNTQVTPGEVSIQLRPGAAANFMLKIHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFFSRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFERAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIVVPNDGNCHLRNNVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGTIAGEIESKAANLNNLVVEAYQKLISEVKVQVESKVPGVYFNVTAICPDGARKLGMEGCSNVTSSDEVLFNVTVTMEKCSVTGGKNYAIIKPIGFNETSKIHIHQNCGCECEASRGGAAKCAEEAPLDSTCPQCQESQCHQEEAQSPSQGCKAHEDQPVCSGRGVCVCGKCLCHKMKLGKVYGKYCEKDDFSCPYHHGSLCAGHGECEAGRCQCFSGWEGDRCQCPSAAAQHCVNSKGQVCSGRGTCVCGRCECSDPRSIGRFCEHCPTCPTACSENWNCVQCLHPHNLSQAILDQCRTSCASMEQPYVEQASECFSSPSYLRIFFIIFIVTFLIGLLKILIIRQVILQWNSSKIKSSSDYRVSASKKDKLILQSVCTRAVTYRREKPEEIKLDISKLNAHETFRCNF
What is the function of this protein?
Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin (By similarity).  It recognizes the sequence R-G-D in its ligands (By similarity).  Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (By similarity).  Required during vasculogenesis (By similarity).
What are the official names of this protein?
Integrin beta-8.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RNZ_BORGP
Sequence: MGFNINIIGTGGTRPLHNRYLSSVLIEYNGDNFLFDCGEGTQMSLRKQKISWQKIKMICITHLHADHITGLLGIVMLMSQSGETRKEPLIIAGPVGIKNYTKTNIDILKIYKNYEIIYKEIIIDKTEKIIYEDKTKKIEYTRLKHSIECVGYLFIEKDKPGKFNTEKAEELNIPKGPIRKTLQDGKEILIDGKIIKPSEILGESKKGLKVAYITDTGYFKELIQQIKNFNLVIIESTFKNELKKEADKKLHLTAGGAANIVKQAKVLKTGLIHFSERYTLRKDLENLLKEAKLEYPDGEIFLTKDGMRLEANKNNFIIK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: DAPF_BART1
Sequence: MKTPFSKMDGLGNQIIVADMRESTQALTPQAILALSADPEMHFDQIMAIRNPTKNEADFHIEIWNADGSKAKACGNGTRCVIAWLTDHNFGENFRLEAPTGIIEGKRQADNLISVDMGCPNFNAKEMPVSREIVDTNHIDITAGPLKDACLISIGNLHAIFFVENDVQHIPLEKYGPKLEHDPLFPERCNISIACITSKKSLNLRTWERGAGLTQACGSAACAGAVAAYRRSLTQRHIDVNLPGGKLNIFYREDDHIIMTGPIKYQFSGFLNPLTGCYKKDNS
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_PARUW
Sequence: MFVDRVIIELIAGKGGNGVVAWRREKYIPKGGPAGGNGGRGGSVILEADTQISSLDWFRHRRILKAQSGGDGGGNCRQGKNGTDLILKVPCGTLLKDAKSGKVIHDFVEDKERFVLCKGGRGGRGNDSFKTPTHQAPNICTEGTLGEIHHIELELKLIADVGLVGFPNAGKSTLISSLAGLRVKVAAYPFTTLQPNLGFIELDNYKRIYIADIPGIIEGASHNRGLGLEFLRHIERTKLLIFILDASGIDGRTPSHDFRILREEIGAYNPELLERPYLVVLNKIDTEDSPSHIQEFEKNFSISSDMLFKISAVYGEGLQELIEKMTQRLSQKKEIEY
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAA_PROM4
Sequence: MTISPPERGEKAKGGVPTPYDQPVDRGNAPVDFEKLNKPGFWSSKLSKGPKTTTWIWNLHADAHDFDTHLGDLEETSRKIFSAHFGHLAVVFIWMSAAFFHGARFSNYTGWLADPTNVKPGAQVVWPVVGQEILNADLGGNYHGLQITSGIFQMWRAWGITSEVQLMALAIGAVVMAALMLHGGIYHYHKAAPKLEWFQKIEPMIQHHQIALIGLGSIAWAGHLIHIGAPVSALLDAIDAGNPLVVDGVSIASASDVTNLAPKLCDPAIASQIFPSLAGRTVENFFTLNWWAFTDILTNKGGLNPVTGSLWMTDISHHHLAFGVFAIFGGHMWRNAVHGVGHSMKEIMDVHKGDPILFPAPKGHEGIFDFLSNSWHGQLSINLAMVGSASIVVAHHMYALPPYPYIAIDYPTVLGLFTHHMWIGGLFICGAAAHAGIAMIRDYDPAIHVDNVLDRMLKARDAIISHLNWVCMWLGFHSFGLYIHNDVMRALGRPQDMFSDTGIQLQPFLAQWVQNLQQSAVGTGQLVGAGNLPGNVLSEVFNGNVIEVGGKVAIGPIPLGTADLMIHHVHAFTIHVTLLILLKGVLYSRSSRLIPDKAQLGFRFPCDGPGRGGTCQVSSWDHVFLGLFWMYNSLSVVIFHFSWKMQSDVWGLTGGNFAQSSITINGWLRDFLWAQSSQVLTSYGQPISMYGLMFLGAHFVWAFSLMFLFSGRGYWQELFESIVWAHNKLKVAPTIQPRALSITQGRAVGVAHFLLGGIATTWAFFHARLIGLG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: GLMU_PROM2
Sequence: MLSVAILAAGKGTRMESSLPKVLHKISGKSLLQRVIDSCVELKPDQIFVITGHKSKEVEKAIPNDKKFHVVVQEPQSGTGHAIQVLCREVKKHQGKLLVLNGDVPLIRPSTLKRLLNLHDSKNADVSLITTKKTHPHGYGRVFLKGDFIERIVEEKDCNDLERENELINAGVYCFNWGILSEIINTLQSNNNQKEIYLTDTISLLKNSLSLEVEDNGELQGINNRIQLSECEEIIQNSIKEKHMLNGVTFINKASCSISEEAEIGKDVIIEANTHIRGNAKINSHCIIGPNTFIENSNVGLNCEISNSTVYASQIMDYIKIGPYSHIRPNSEISSFSKIGNFVEIKNSQLEEESKVNHLSYIGDSIIGRSTNIGAGTITANFDGQKKHQTKIGKNSSIGANTVFVAPINLGESVTTGAGSVITKDSKDNSLAISRTEQVNIENWERKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR9_TYRGL
Sequence: GRGASSNYVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-9, FMRFa-9.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PPCEL_MACFA
Sequence: MQQKTKLFLQALKYSIPHLGKCMQKQHLNHYNFADHYYNRIKLKKYHLTKCLQNKPKISELARNIPSRSFSCKDLQPVKQENEKPLPENMDAFEKVRTKLETQPQEEYEIINVEVKHGGFVYYQEGCCLVRSKDEEADNDNYEVLFNLEELKLDQPFIDCIRVAPDEKYVAAKIRTEDSEASTCVIIKLSDQPVMEASFPNVSSFEWVKDEEDEDVLFYTFQRNLRCHDVYRATFGDNKRNERFYTEKDPSYFVFLYLTKDSRFLTINIMNKTTSEVWLIDGLSPWDPPVLIQKRIHGVLYYVEHRDDELYILTNVGEPTEFKLMRTAADTPAIMNWDLFFTMKRNTKVIDLDMFKDHCVLFLKHSNLLYVNVIGLADDSVRSLKLPPWACGFIMDTNSDPKNCPFQLCSPIRSPKYYTYKFAEGKLFEETGHEDPITKTSRVLRLEAKSKDGKLVPMTVFHKTDSEDLQKKPLLIHVYGAYGMDLKMNFRPERRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLEACIKTLHGQGFSQPSLTTLTAFSAGGVLAGALCNCNPELLRAVTLEAPFLDVLNTMMDTTLPLTLEELEEWGNPSSDEKHKNYIKRYCPYQNIKPQHYPSVHITAYENDERVPLKGIVSYTEKLKEAISEHAKDTGEGYQAPNIILDIQPGGNHVIEDSHKKITAQIKFLYEELGLDSTSVFEDLKKYLKF
What is the function of this protein?
Serine peptidase whose precise substrate specificity remains unclear (By similarity).  Does not cleave peptides after a arginine or lysine residue (By similarity).  Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex (By similarity).  May play a role in the regulation of synaptic vesicle exocytosis (By similarity).
What are the official names of this protein?
Prolyl endopeptidase-like, Prolylendopeptidase-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9A family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus, trans-Golgi network. Cytoplasm, cytoskeleton. Golgi apparatus. Nucleus. Note=Co-localizes with AP-1 in the trans-Golgi network (By similarity). Co-localizes with MAP2 and ACTB on the cytoskeleton (By similarity). Co-localizes with STX6 and GOSR2 at the Golgi apparatus (By similarity).
Protein: MURB_HELPY
Sequence: MLETTIDFSRYSSVKIGTPLKVSVLENDDEISQEHQIIGLANNLLIAPSAKNLALLGKNYDYICDKGECVEIGGAANASKIFNYFRANDLEGLEFLGQLPGTLGALVKMNAGMKEFEIKNVLESACINNQWLEKEALGLGYRSSGFSGVVLRARFKKTHGFREGVLKACQSMRKSHPKLPNFGSCFKNPPNDHAGRLLEGVGLRGYCLKRVGFAKEHANFLVNLGGAEFEEALDLIELAKARVLQEYGIHLEEEVKILR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3I_CHAGB
Sequence: MRPILLAGHERALTQIKYNPDGDLIFSVSKDQQICVWFAHNGERLGTYRGHQGAIWTIDVDPTSTILASGSADNTIRLWDIKTGKCLKTWDFPTAVKRVEFNEDGTKLLGVTEKRMGHLGTIVVLDIKIDVEAEQSDEKVMTIVCDESKATVAGWSYLSKYIIAGHEDGSVSQYDGKTGDLLYNIPIHELNQPITDLQWSQDRTYFITASKDKTSKLISSKDLEVLKSYTADTPLNSAAITPKKDFVILGGGQAAMDVTTTAARQGKFEARFYHKIFEDEIGRVRGHFGPLNTVAADPTGKGYASGGEDGYVRVHAFDKGYYDFLYEVERERQNRLAAASA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 39 kDa subunit homolog, eIF-3 39 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF4_TTVE1
Sequence: MTQKDWGEENQGMLTGATWLDECQSAYLWGRKPRHSWADPPESLDNWSFKTHPFHPWRINFTLTPPPETP
What are the official names of this protein?
Uncharacterized ORF4 protein.
Protein: DAAF1_ANOGA
Sequence: MTKKTIQASCRKNKLYLTPHLNDVLYLHYSGYNAIDGLDEYVGLKCLWLECNAISNISGLDHQSQLRCLYLHNNLIKKIENLQHCKQLDTLNLSHNHIAKIENCGSDILPVLNTLNISHNYLKSIESLAELRKCDFVSVLDISHNRIEDIAIVKVLADMKGLRVLTLVGNPVVNDIPSYRKTLILECKSLTYLDSRPVFDKDRACAEAWKRGGYEEERKEHQRWKKEEQRKMRRSINATLRLRHRGDGEPELLKTSSDEEEEEKEGSAAGRGDFEELEYQSNDVAWKEMEALFNQHTKGDTQQAQKLAEERKASTNSVDYITGSDSNSDPTLVTDCDSCVRNSSRACSSRSDTSDSEDMFDKIVPKKHRKLASSMRPEVSLSDSSSSSSETEDEAGSILDSKLDRQNTITEFIDEYKRFFHSVDLRDPKCVLKNRHKIVRPQTAKSQRTEPIVYEGVLKAMEQNSNGAKIEQARQERFEANERSLAKEAVLERLMKGHAEVDMNIEQQMISIGGKQHNFNEYRLEVFRQDQEKLQNLIDRVTAQKEKYNAHIDSIHDQLANIMEDYGQISEKLRKVDDMIQNIGDEVVVHQEKERDGLEVIQELEPITIAEQIVENMTKEQVPDEVEANDKASDATIDPVDQLSSDESAIDLGELNQHVDAQVEVGPSDPKDATTSKPIPEEFGSDPVYRKFIDIQYEIDKLTEDQIFTALSEAARELQEEELETKLVHDAIDEYWSTDLEDFRRNLNLDAHPIVQRFKRFIECQGTDTDDTDSEAHVRRLENAYHRYERRLSNHLFDEYLMLSRKASIATTTGGESSATELELVELDGGHVLRASTSRRATAWDLKETVEDPVEELEELNEEEDPALKEAGDFKHDELEDEESKPEEKTLKSAEVLGMQEPLADVQGDH
What is the function of this protein?
Cilium-specific protein required for cilia structures.
What are the official names of this protein?
Dynein axonemal assembly factor 1 homolog, Leucine-rich repeat-containing protein 50.
What is the protein family that this protein belongs to?
Belongs to the DNAAF1 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: MIAB_BORBR
Sequence: MQETTVKRDGASPSDAGTPATTAQGLGKLYIRTFGCQMNEYDSDKMADVLRADQGLELTDNPEDADVILFNTCSVREKAQEKVFSDLGRVQHLKKQNPNLVIGVGGCVASQEGEAIVKRAPYVDVVFGPQTLHRLPDLIKRRRAQGVSQVDISFPEIEKFDALPPPRVDGATAFVSIMEGCSKYCSFCVVPYTRGEEVSRPFDDVLLEVADLADQGVKEVTLLGQNVNAYRGAMGDSGEIADFAMLLEYVHEIPGIERIRYTTSHPKEMTQRMVDAYARLPKLVSFLHLPVQAGSDRVLAAMKRGYTALEFKSVVRRLRAARPSLTLSSDFIVGFPGETEEDFQKTMKLIEDVGFDTSFSFVYSRRPGTPAADLHDDTPQDVKLRRLQQLQALINQQAAAIAQGMIGTRQRVLVEGPSRRDPNELMGRTENNRIVNFPGVPRLIGHMVDVVVTHAHTNSLRGRVAGIERDTSGAE
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPD1_BRADU
Sequence: MKYSSEFRDKTIAQGLARAIDAEVSSQRAYRFVEFCGGHTHAISRYGLEDLLPANVRMIHGPGCPVCVLPASRIDMAIRLAERPEVILCVYGDLMRAPGSQGQSLLLAKALGAHIRMVYSTLDAIRLAEQTPGREVVFFAIGFETTTPPTAVMIRIAEHKRLEGLSVFCNHVLTPSAMHRILENPKIRNTGGVPIDGFIGPAHVSTIVGTQPYEPMAEQFEKPIVVAGFEPLDVLQAVLMLVRQVNQNRHEVENQYSRAVTREGNRRAKEEVSQVFELREQFEWRGLGLVPNSGLKLKQSYAKFDAETRFAIHDLRVADNPACECCAILRGAKRPIDCKLFGNICTPETPIGACMVSSEGACAAYWTYRRVRDEQARQTS
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Involved in the biosynthesis of the Fe(CN)(2)CO cofactor.
What are the official names of this protein?
Hydrogenase maturation factor HypD1.
What is the protein family that this protein belongs to?
Belongs to the HypD family.
Protein: UNG_PROMH
Sequence: MTTPLTWHDVIGAEKEKPYFQQILSQVAQQRQAGKIIYPPQEDVFNAFRFTPFENVNVVILGQDPYHGPNQAHGLSFSVRPGVPAPPSLVNMYKELEQEYPDFKRPNHGYLESWAQQGVLLLNTVLTVEKGQAHSHANYGWEVFTDAVIEQINQRREGVIFLLWGAHAQKKGRFIDTNKHFILKAPHPSPLSAHRGFLGCGHFKQTNNLLAQQGRTPINWQLDPIE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAL1_MOUSE
Sequence: MAKATTIKEALSRWEEKTGQKPSDAKEIKLYAQIPPIEKMDASLSTLGNCEKLSLSTNCIEKIANLNGLKNLRILSLGRNNIKNLNGLEAVGETLEELWISYNFIEKLKGIHVMKKLKILYMSNNLVKDWAEFLKLAELPCLEDLVFVGNPLEEKHSAEGNWIDEATKRVPKLKKLDGTPVIKEDEEEES
What is the function of this protein?
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity).  Component of the outer arm dynein (ODA).  May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity).  Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (By similarity).
What are the official names of this protein?
Dynein axonemal light chain 1.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain LC1-type family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: FTSK_BACCR
Sequence: MAKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWYIIGVLGVIALSVSFVIKRGWPNLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTSVIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFDEVGAYIIGIILVILGILCITNKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRAAEQEEIIEPMEEISIDPPIISNFTENYPVNEEEDKRIEVEQEELITSPFIEETPPIEEPKKKRGEKIVESLESEAQAPPMQFSNVENKDYKLPSLDILKFPKNKQVTNENAEIYENARKLERTFQSFGVKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVSLSDDLALALAAKDIRIEAPIPGKSAVGIEVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSGKSVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKVVSEMERRYELFAHSGTRNIEGYNDYIKEHNSQSEAKQPELPYIVVIVDELADLMMVASSDVEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDGGGAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVLDTKQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKPREVLINDVQEKSS
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: MNMG_COXBR
Sequence: MQSTSQQFDVIVVGGGHAGTEAALVAARMGARTLLLTHNIETLGQMSCNPAIGGIGKSHLVKEIDALGGIMALAADQAGIHFRTLNARKGPAVRATRAQADRVLYKAAIHHALENQPHLWLFQQGVDDLIIQNNRAAGVVTQMGLAFYAPTVILTVGTFLGGKIHIGMNHYRGGRAGDPPALALAERLREMPFRVERLKTGTPPRIDGRTINYSQLIEQPSDQPLPLMSYWSHGEDRPRQVSCFITQTNEKTHDIIRNGLKTSPLFSGVIEGVGPRYCPSIEDKIVRFADRNSHQLFLEPEGLNTPEVYPNGVSTSLSFDVQLDFIHSIKGLEKCHITRPGYAIEYDYFDPRDLKPSLETKYVPGLYFAGQINGTTGYEEAAAQGLIAGINAALQIQERAPWTPARDEAYIGVLIDDLTTRGTNEPYRMFTSRAEYRLLLRQDNADLRLTEKGRDLGCVDDERWNFFVKKKETIEKEQQRLKKQRIWPKSTVAKAIESRFQQLLERDYSAMDLLRRPEINYPALMQIEELGPAVLEPSVAEQIDIQAKYEGYLTHQLAEIARQKKYQTAQIPSSLDYNQVTGLSNEVRQKLNETKPTTLGQASRIPGITPAAISLLLVHLKKKELYP
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCP_STAAM
Sequence: MHILVTGFAPFDNQNINPSWEAVTQLEDIIGTHTIDKLKLPTSFKKVDNIINKTLASNHYDVVLAIGQAGGRNAITPERVAINIDDARIPDNDDFQPIDQAIHLDGAPAYFSNLPVKAMTQSIINQGLPGALSNSAGTYVCNHVLYHLGYLQDKHYPHLRFGFIHVPYIPEQVIGKPDTPSMPLEKIVAGLTAAIEAISNDEDLRIALGTTE
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_CAMJ8
Sequence: MRALALDVGLKRIGVALCIDKKIALPLDAVLRKNRNQAANEIKNLLKIHEISLLIVGIPKGGSSEEEMTRRIKHFVSLLEFDKEICFVDESGTSKEALGYGVANTRKKDGKLDSLSAFIMIKDYFAL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_ECOUT
Sequence: MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCSVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.