PharMolix/UniProtQA huggingface dataset:
Protein: MLH3_ARATH
Sequence: MKTIKPLPEGVRHSMRSGIIMFDMARVVEELVFNSLDAGATKVSIFVGVVSCSVKVVDDGSGVSRDDLVLLGERYATSKFHDFTNVETASETFGFRGEALASISDISLLEVRTKAIGRPNGYRKVMKGSKCLHLGIDDDRKDSGTTVTVRDLFYSQPVRRKYMQSSPKKVLESIKKCVFRIALVHSNVSFSVLDIESDEELFQTNPSSSAFSLLMRDAGTEAVNSLCKVNVTDGMLNVSGFECADDWKPTDGQQTGRRNRLQSNPGYILCIACPRRLYEFSFEPSKTHVEFKKWGPVLAFIERITLANWKKDRILELFDGGADILAKGDRQDLIDDKIRLQNGSLFSILHFLDADWPEAMEPAKKKLKRSNDHAPCSSLLFPSADFKQDGDYFSPRKDVWSPECEVELKIQNPKEQGTVAGFESRTDSLLQSRDIEMQTNEDFPQVTDLLETSLVADSKCRKQFLTRCQITTPVNINHDFMKDSDVLNFQFQGLKDELDVSNCIGKHLLRGCSSRVSLTFHEPKLSHVEGYESVVPMIPNEKQSSPRVLETREGGSYCDVYSDKTPDCSLGSSWQDTDWFTPQCSSDRGCVGIGEDFNITPIDTAEFDSYDEKVGSKKYLSSVNVGSSVTGSFCLSSEWSPMYSTPSATKWESEYQKGCRILEQSLRLGRMPDPEFCFSAANNIKFDHEVIPEMDCCETGTDSFTAIQNCTQLADKICKSSWGHADDVRIDQYSIRKEKFSYMDGTQNNAGKQRSKRSRSAPPFYREKKRFISLSCKSDTKPKNSDPSEPDDLECLTQPCNASQMHLKCSILDDVSYDHIQETEKRLSSASDLKASAGCRTVHSETQDEDVHEDFSSEEFLDPIKSTTKWRHNCAVSQVPKESHELHGQDGVFDISSGLLHLRSDESLVPESINRHSLEDAKVLQQVDKKYIPIVACGTVAIVDQHAADERIRLEELRTKVLAGKARTVTYLSADQELVLPEMGYQLLQSYSEQIRDWGWICNITVEGSTSFKKNMSIIQRKPTPITLNAVPCILGVNLSDVDLLEFLQQLADTDGSSTIPPSVLRVLNSKACRGAIMFGDSLLPSECSLIIDGLKQTSLCFQCAHGRPTTVPLVDLKALHKQIAKLSGRQVWHGLQRREITLDRAKSRLDNAKS
What is the function of this protein?
Involved in DNA mismatch repair (MMR), correcting insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis.  Component of the MutLbeta heterodimer, which probably forms a ternary complex with the MutSbeta heterodimer that initially recognizes the DNA mismatches.  This complex is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  Plays a major role in promoting meiotic crossing-over and is involved in maintaining the genetic stability of simple sequence repeats by correction of frameshift intermediates.
What are the official names of this protein?
DNA mismatch repair protein MLH3, MutL protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS8_HAHCH
Sequence: MSMQDTLADMFTRIRNAQMAEKETVRMPSSKMKVAVANVLKEEGFITDYKASEEAKPVLEITLKYYQGAPVIENISRASRPGLRQYKAANDLPTVNGGLGIAIVSTSKGVMTDRAARKAGVGGEVICTVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SCD_HUMAN
Sequence: MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDDIRPDIKDDIYDPTYKDKEGPSPKVEYVWRNIILMSLLHLGALYGITLIPTCKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLMMCFILPTLVPWYFWGETFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNYHHSFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284).  Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284).  Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069).  Plays an important role in lipid biosynthesis.  Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity).  Plays an important role in body energy homeostasis (By similarity).  Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).
What are the official names of this protein?
Stearoyl-CoA desaturase, hSCD1, Acyl-CoA desaturase, Delta(9)-desaturase, Delta-9 desaturase, Fatty acid desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: COAA_ENTH1
Sequence: MSGFDLSEVAGPVAEVIDDKNEEVEFVVFGVQTQPNKLVVDAKGKGGLEEVKAALKEDALQFAYYRTISGDEESKRVKFVFISWAGEGIKKPKLRAVMSILKGDVKNVINNFHIELHATSLDDLVEDEIAAKIKKAGGADYSFNTTSN
What is the function of this protein?
Actin-binding protein which is involved in F-actin stabilization (PubMed:25210743).  May play a role during phagocytosis and pseudopod formation by contributing to the maintenance of F-actin (PubMed:25210743).
What are the official names of this protein?
Coactosin.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. Coactosin subfamily.
Protein: Y015_METJA
Sequence: MMRLNWQIRQVQLLLERLGLQQLVWMDCLVMMLNKAIFLDRDGVINKRLIGDYVKKIEEFELLPNVREALIEFKKMGYLLIVVTNQQGSKQFLIFYNL
What are the official names of this protein?
Uncharacterized protein MJ0015.
Protein: MIAA_YERPE
Sequence: MNDIENLDRPPAIFIMGPTASGKTALSIALRQRLPVELVSVDSALIYRGMDIGTAKPSAQELALAPHRLIDIRDPAESYSAADFRKDALKEMADITAAGRIPLLVGGTMLYFKALLDGLSPLPSADPQVRQRIEQQASELGWGALHQQLAVIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTKISGETLPYRVHQFAIAPASRELLHQRIELRFHQMLDAGFEAEARVLFDRGDLHTDLPAIRCVGYRQMWSYLSGEIDYNDMVYRGVCATRQLAKRQMTWLRGWSSVQWLDSDKPGEALDSVIQVVSA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GPR_BACSU
Sequence: MKKSELDVNQYLIRTDLAVETKEAMANQQAVPTKEIKGFIEKERDHGGIKIRTVDVTKEGAELSGKKEGRYLTLEAQGIRENDSEMQEKVSAVFAEEFSAFLENLNISKDASCLIVGLGNWNVTPDALGPMAVENLLVTRHLFKLQPENVQEGYRPVSAFAPGVMGITGIETSDIIKGVIEQSKPDFVIAIDALAARAVERVNTTIQISDTGIHPGSGVGNKRKDLSKDTLGVPVIAIGVPTVVDAVTIASDTVDYILKHFGREMKDNRPSRSLVPAGMTFGKKKVLTEDDLPDQKQRQSFLGIVGTLQEDEKRQLIHEVLSPLGHNLMVTPKEVDSFIDDMANVLANGLNTALHEKVSQENKGSYNH
What is the function of this protein?
Initiates the degradation of small, acid-soluble proteins during spore germination.
What are the official names of this protein?
Germination protease, GPR endopeptidase, Germination proteinase, Spore protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase A25 family.
Protein: RS182_MYCPA
Sequence: MPKKPARTRRPAPLAGRARKKNLLDSLGLRTVDYKDTATLRVFISERGKIRSRQVTGLSVQQQRQVATAIKNAREMALLPYPGQGIKP
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y951_STAA8
Sequence: MILGLALIPSKSFQEAVDSYRKRYDKQYSRIKPHVTIKAPFEIKDGDLDSVIEQVRARINGIPAVEVHATKASSFKPTNNVIYFKVAKTDDLEELFNRFNGEDFYGEAEHVFVPHFTIAQGLSSQEFEDIFGQVALAGVDHKEIIDELTLLRFDDDEDKWKVIETFKLA
What are the official names of this protein?
Putative phosphoesterase SAOUHSC_00951.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: STE2_YEAST
Sequence: MSDAAPSLSNLFYDPTYNPGQSTINYTSIYGNGSTITFDELQGLVNSTVTQAIMFGVRCGAAALTLIVMWMTSRSRKTPIFIINQVSLFLIILHSALYFKYLLSNYSSVTYALTGFPQFISRGDVHVYGATNIIQVLLVASIETSLVFQIKVIFTGDNFKRIGLMLTSISFTLGIATVTMYFVSAVKGMIVTYNDVSATQDKYFNASTILLASSINFMSFVLVVKLILAIRSRRFLGLKQFDSFHILLIMSCQSLLVPSIIFILAYSLKPNQGTDVLTTVATLLAVLSLPLSSMWATAANNASKTNTITSDFTTSTDRFYPGTLSSFQTDSINNDAKSSLRSRLYDLYPRRKETTSDKHSERTFVSETADDIEKNQFYQLPTPTSSKNTRIGPFADASYKEGEVEPVDMYTPDTAADEEARKFWTEDNNNL
What is the function of this protein?
Fungal class D1 G-protein-coupled receptor that acts as an alpha-factor pheromone receptor performing pheromone-dependent signal transduction involved in cellular conjugation, mating projection assembly, and in cell fusion (PubMed:4595644, PubMed:6993497, PubMed:6353246, PubMed:6360378, PubMed:3023832, PubMed:3037311, PubMed:2842059, PubMed:2839507, PubMed:2556384, PubMed:9286665, PubMed:9824658, PubMed:9529386, PubMed:9742115, PubMed:9819407, PubMed:10744981, PubMed:11495900, PubMed:12427030).  Following alpha-factor-binding, the signal is transmitted via a tripartite G protein consisting of alpha-, beta- and gamma-subunits (GAP1, STE4 and STE8 respectively) that prepares the cell for conjugation (PubMed:1647971, PubMed:1330324, PubMed:8385135, PubMed:8132618, PubMed:8692892, PubMed:10866688, PubMed:11287148).  In the inactive state, the cytoplasmic end of transmembrane domain 7 (TMD7) is unstructured and packs between TMD1-6, blocking the G protein coupling site (PubMed:35296853).  Agonist binding results in the outward movement of the extracellular ends of TMD6 and TMD7 by 6 Angstroms (PubMed:35296853).  On the intracellular surface, the G protein coupling site is formed by a 20 Angstroms outward movement of the unstructured region in TMD7 that unblocks the site, and a 12 Angstroms inward movement of TMD6 (PubMed:35296853).
What are the official names of this protein?
Pheromone alpha factor receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FABZ_PROM9
Sequence: MDNKLSSENNQLSSEKILGLLPHRYPFALVDKVIENIPGERAVAVKNVTINEPQFQGHFPERPLMPGVLIVESMAQVGGIIVTQMPDLPKGLFVFAGINNVKFRKPVLPGDQLIITCDLLSIKRQRFGKVKGEAHVDGNLVCAGELMFSLVD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_ACIBY
Sequence: MSNATKFGKVAVLLGGKSAERAVSLDSGQAVLDALLRSGVQAEAFDPQNRSVTELVNYDRAFIVLHGRGGEDGQIQGVLEWLNIPYTGTGVQGSAIGMDKVKTKQIWQGSDLPTAPYRIITKETDLDSVIAELGLPVIIKPVHEGSSVGMSKVEKAEDFAAAIEKATQHDAVVMAEKWITGREFTISFLNGQPLPVIRLQPPADVAFYDYEAKYQRNDVEYGIPCGLSETEEKKLQALCLRAFQAVGAEGWGRIDAMQDEQGNFWLLEVNTVPGMTSHSLVPKAAKAVGYSFDELCVAILDQTLEGTA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOLIN_BPMD2
Sequence: MSPKIRETLYYVGTLVPGILGIALIWGGIDAGAAANIGDIVAGALNLVGAAAPATAAVKVNQQRKDGTLTTSPVDQVTRGVEQVLAAKQNAEAEVERVKQALESAVNGAVPQLGPLASQILNGIQPAYSQPFDPHTQPWNR
What is the function of this protein?
Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space (Probable).  Determines the precise timing of host cell lysis (PubMed:32477303).  Participates with the endolysin protein in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell (PubMed:26471254).
What are the official names of this protein?
Holin, Gene product 11, gp11.
What is the protein family that this protein belongs to?
Belongs to the Mycobacterium phage D29 holin family.
What are the subcellular locations of this protein?
Host cell inner membrane; Multi-pass membrane protein.
Protein: HISX_SHIDS
Sequence: MSFNTIIDWNSCTAEQQRQLLMRPAISTSESITRTVNDILDNVKARGDEALREYSAKFDKTTVTALTVSAEEIAAASERLSDELKQAMAVAVKNIETFHTAQKLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCKKVVLCSPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPAADMARRVAEAVERQLAELPRAETARQALSASRLIVTKDLAQCVEISNQYGPEHLIIQTRNARVLVDGITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTVQELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: ADDA_LACP3
Sequence: MTQFTTSQQAAITHDGHDVLVSASAGSGKTTVLVERIIQKILKQHADITRMLIVTFTRAATAEMRTKIQTALKKALTERRHELSGEDRRHLANQIAMVNAAKISTLDAFSLQIVQTYYYVIDLDPGFRLLTDETERYMLQERVWDDLREQLYASDEAPAFEQLTANFSGDRDDSGLQDLMFELIRQAGATTDPKAYLEGLATPYAPEKWEATFSQQIWPRVKGQLLQIATSLTQASALANQLPNPIWYQQIQADLAPLQTLLETNAPTYDTVRSVLISHEFAAWSRISKGLDDADKDTKNAAKDLRDAAKKTWQNKLAPTFALAAEQIGDLLREAQPLVATLANVALKFEDALTAEKAARHVQDYSDIAHNALRILQQKDPQTGAPIADNYRASFDEVMVDEYQDISPLQEALLAAVSTTTPGDRFMVGDVKQSIYGFRLADPQLFIHKYQTFQDAPTDPAAPERIILAENFRSTKNVLAFTNLIFSQIMDPEVGDLSYDNAAALKYGALDYGDAHPAVKVLLYSKATSDEDSSDASELPGDADDNEPVDIATGQTQLVLAEIQRLINDPDAQLWDRQAQEYRRIHYRDITLLTRQTSQNSLIQTQFAAAGVPLFVADTKNFFKTTELMVMLALLKVIDNQKQDIPLVAVLRSPIVGLSADQLALIRLAAKQVPYYDAVTAFLQAEPKTPLAQRTHDMLTHFFNQLSHFRDLARENDLVTLLWAIYQDTGFLDYVGGTPGGSQRQANLQALIDRARTYEAGGFKGLFAFIHFITLMQKQDQDLAMPAQVDPDNDAVKLMTIHKSKGLEFPVVFLMQANKHFNMSDQTGTAILTKQGIGIKWLDPETRVEYELPQYQAAKAARQNQTLAEEMRLLYVALTRAQQRLYVVGATMSGNQLTSADKTVEKWAAAAEGEARVLAPQVRSGATSYLDWIGPALIRHPQARGLAETTIKPALVGDETEFTIEIDVNPQVTPTATPEKVSDDSGTMVDLSAWFKKAYPFQAATTTTGFQSVSEIKRAFDDPDTIDLVNADRFLGPKPPMRDLTAPAFLTETPSGISPAAIGTATHLLLQLVDLAKPITMASLRALRDQLTTTQVIAVDVAKHIDLTALIRFFETDLGRLLLAKPQQVHREVPFSMLLPADQVFEALADDPGEDVLIHGIIDGYVSDEQGVTLFDYKTDHNPNTAVLVDRYRGQLNLYAQALQDLQPKPVLHRYLVFLRTGTVVDLVASGAGK
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: LASP1_RABIT
Sequence: MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGRGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGAEPERRDSQDSSNYRRPPEQQQPPQPHHIPTSTPAYQQPQPQQVAQSYGYKEPAAPVSTQRGAPGGGGKRYRAVFDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI
What is the function of this protein?
Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities.  Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).
What are the official names of this protein?
LIM and SH3 domain protein 1, LASP-1, 40 kDa phosphoprotein, pp40.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Associated with the F-actin rich cortical cytoskeleton.
Protein: SFSA_SACS2
Sequence: MNESNSQDLTRVSPFYIKEGFSVYEFTEKLFEAYVIERINRFLVKVTLDGEEILVHLHDPGRLKELIYPGNLVLIRETKGNKTKFSITAAYANSRFIVLDSRLHNIIASKFIPKIYEKEVKVGNSRIDFKYDNTYLEVKGCTLVENEIAYFPDAPTERGRKHLKELRELMRKGFNAILLILVMRNDAKCFLPNEKTDPKFSVEFWDSIKEGLKVYIKTFSLIGNKIVYVGDIPLCKTNLT
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: IES4_SCHPO
Sequence: MSETLVLHLKVPTERFREVLSSLKEKQNFTASPSSQPKPQERPFQMKKPRAPYGMGPRAMKRREKAEKEKLGVVNDELAESSKPSSGAATPTRSAPKSSAGLINSGLRALDRSGKPCRRWEKKPISIRSISTIVWKLPLWIGTPDSIPNTPELPVKTTLDSVNEIAAALSTHAESSPMDATSPVDSMPESATGI
What is the function of this protein?
Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
What are the official names of this protein?
INO80 complex subunit 4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: OBG_WOLSU
Sequence: MFVDNVDIYVSSGKGGAGAVSFRREKYVIQGGPDGGDGGKGGDLYFEVNANTDTLSKFKGAKHYRAKNGQPGMGRRMSGKSGEEMVIVVPPGTQVFDYESNELLLDLKEEGMRVKFLEGGKGGLGNYHFKNSVNQRPTYAQPGIAGEERHVRLELKLIADVGLVGFPNVGKSTLISTLSNARPEVANYEFTTLIPALGVVDVDEFSSFVMADIPGIIGGASEGKGLGLEFLRHIERTKTLLFVIDLSNYREPLEQFEILQKELSQFSPELSLRPFGIALSKVDALSKEEANEKIELFLKGIGLSSCQSNQYALSEALQNYIAPLESSIPAFVVPISSATHENIKPLKYLLHESVRRRG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_POLNA
Sequence: MSLRIYNTLSRAVEDFSPLVPGQVRMYVCGMTIYDLCHIGHARMMMAFDVVQRWLKASGYEVRYVRNITDIDDKIIKRAVERGITIRALTDEMIAAMHQDIGALGIEPPTLEPRATEYVPQMLAMIGKLEEKGLAYRGSSGDMNYAVRKFPGYGKLSGKSLDELRAGERVAVLEGKDDPLDFVLWKSAKESEPEDAKWDSAALGHDYGKGRPGWHIECSAMSCQTLGETFDIHGGGADLQFPHHENEIAQSEGANGKPLARFWVHNGFVRVDNEKMSKSLGNFFTIRDVLQKYDAETIRFFIIRAHYRSALNYSDAHLDDARNSLKRLYTALALVAPATVEIDWADPFAARFKAAMDEDFGTPEAIAVLFELAGEVNKTHSAERAGLLKSLGACLGLLQGEPSAYLQAGAGLDDAAIQALITQRADAKKARDFAAADRIRTELLGQGIVLKDSPLGTTWEVQS
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXF07_LYCSI
Sequence: MNSKIFAVLLLLAFLSCVLSDQYCPKSSITACKKMNIRNDCCKDDDCTGGSWCCATPCGNFCKYPTDRPGGKRAAGGKSCKTGYVYY
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
U15-lycotoxin-Ls1f, Toxin-like structure LSTX-N7.
What is the protein family that this protein belongs to?
Belongs to the venom protein 11 family. 01 (wap-1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYOE_LEGPL
Sequence: MRTEYADRLPVDWRDYVELCKPRVVLLMLLTVIVGMYLAAPGWVSLRLIAFTLLGIGLCAGSAAAINHLVDRHIDSIMARTKKRPVAYGRVSVKQALWFAVIIGLMGLSLLILFVNQLTALLTFITLIGYAGVYTGYLKRATSQNIVIGGLAGAAPPLLGWTAVTDQLDPQALLLVLIIFTWTPPHFWALAIYRYKEYQDAEIPMLPVTHGIQFTKLNIYLYTVLLLVVSLLPFVVSMSGWIYLLGALILGIRFLVWAHKLYFTDKPVVAMQTFRFSILYLMLLFVFLLVDHYF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CML40_ARATH
Sequence: MKSENVNKRDEYQRVFSCFDKSHQGKVSVSTIERCVDAIKSGKRAVVDQEDTTNPNPEESTDDKSLELEDFVKLVEEGEEADKEKDLKEAFKLYEESEGITPKSLKRMLSLLGESKSLKDCEVMISQFDINRDGIINFDEFRAMMQ
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML40, Calmodulin-like protein 40.
Protein: RCAS1_MOUSE
Sequence: MAITQFRLFKVCTCLATVFSFLKRLICRSGRGRKLSGDQITLPTTVDYSSVPKQTDVEEWTSWDEDAPTSVKIEGGNGNVATQQNSLEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGVPDGSTGFSSRLAATQDMPFIHQSSELGDLDTWQENSNAWEEEEDAAWQAEEVLRQQKIADREKRAAEQQRKKMEKEAQRLMKKEQNKIGVKLS
What is the function of this protein?
May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
What are the official names of this protein?
Receptor-binding cancer antigen expressed on SiSo cells, Cancer-associated surface antigen RCAS1, Estrogen receptor-binding fragment-associated gene 9 protein.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type III membrane protein. Note=Predominantly located in the Golgi.
Protein: AT1A3_MOUSE
Sequence: MGDKKDDKSSPKKSKAKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCATILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients (By similarity).
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS132_ARATH
Sequence: MGRMHSRGKGISASALPYKRSSPSWLKTTSQDVDESICKFAKKGLTPSQIGVILRDSHGIPQVKSVTGSKILRILKAHGLAPEIPEDLYHLIKKAVAIRKHLERNRKDKDSKFRLILVESRIHRLARYYKKTKKLPPVWKYESTTASTLVA
What are the official names of this protein?
40S ribosomal protein S13-2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SLYX_XYLFM
Sequence: MHEKLLTLCDCAFEARLIELEMRVSFQEQALTEISEALAETRLIGARNAELMRHLLEELGKVRNTLYEHPIDEPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: COAA_STRPN
Sequence: MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISLQDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSRLLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIKNGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNLQNYIEPTRNRAEVILHKSKNHEIDEIYLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.