PharMolix/UniProtQA huggingface dataset:
Protein: PSD_NITHX
Sequence: MSIDRQTLLSVAKSIRSGAKSIRAQISPIHPKGYPFVGGFALASIILFWIWTPLGWIGTLLTIWCALFFRNPARVTPVREGLVVSPADGRISMIAPVVPPAELELGEQPMVRISIFMSVFNCHVNRSPVAGKIERIVYRPGKFINAELDKASEDNERNSLVISTPNNGLVGVVQIAGLVARRIVTFVHDGQTLETGERFGLIRFGSRLDVFLPEGTQLLVSEGQTAIAGETVLADFQQADGGRTYRSN
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GPDA_BURL3
Sequence: MKVAVLGAGAWGTALAGHLAARHDTLLWARDAALIAGLQARHENSRYLDGIALPDALRYDADLGAALAHGAADDALCVIAAPVAGLRTLCHAMRDAGCVPAHVVWVCKGFEADTHLLPHQVIAAELPEQHSNGVLSGPSFAREVGQSLPVALTVASTSAECRERTLAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALITRGLAEMSRLGVALGGRAETFTGLTGLGDLILTATGDLSRNRTVGLQLAAGRTLNDILGALGHVAEGVRCAQAVLAIARAQSIEMPITEAVCGVLFDGIAPRDAVSGLLRRDARAE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFA5_EMENI
Sequence: MAGQPDRRINLAVARVIPVVLFGIIIYSCYVITKPLCIDYLIDPLPKYNRPSRVGAGAAILVVFYILLLFVIITYVRLLYTVVYNPDLLPRSQAADQQSTPAKRSKSRSRRKGHGHGHRKSKSDEVSDKPVSDVERALDYNAGPMVLPWDTAGLEYFYKKDVFVCQPDGRPIYCSKCCHYKPDRTHHCREVDRCVRKMDHFCPWVGGVVSETSFKFFIQFVFYTALFCMTVLIVCAIYTAELRQDVSLISGSRNMLIISRLVMLTLIGLSDSLQLAAFNLTTIENLNRRSAVWTLAIRVPNHMISRIQPGTRWAPTFRTITYPLPPVPPPLSGMPTQPATGEGDNPYSPPPVPSTDPSAEQHIFAILQTLPGENPFALGSPLKNLQQVLGHSIIDWLLPIKRSPCADHSSAESEFVMGPVVSRLKKEAGLESKDAAAGSITTKHKNSSYNSSPSAPADKRSKRKQKRGKHHHHHHHHRHSSTTGTT
What are the official names of this protein?
Palmitoyltransferase pfa5, Protein fatty acyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COPA2_HELPX
Sequence: MKESFYIEGMTCTACSSGIERSLGRKSFVKKIEVSLLNKSANIEFNENETNLDEIFKLIEKLGYSPKKTLAEEKKEFFSPNVKLALAVIFTLFVVYLSMGAMLSPSLLPESLLTINNHSNFLNACLQLIGTLIVMHLGRDFYIQGFKALWHRQPNMSSLIAIGTSAALISSLWQLYFVYTSQWSYGHYYFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKTALKMHNNQQIEVLVDSIVVGDILKVLPGSAIAVDGEIIEGEGELDESMLSGEALPVYKKVGDKVFSGTFNSHTSFLMKATQDNKNSTLSQIVEMIHNAQSSKAEISRLADKVSSVFVPSVIAIAILAFVVWLIIAPKPDFWWNFGIALEVFVSVLVISCPCALGLATPMSILVANQKASSLGLFFKDAKSLEKARLVNTIVFDKTGTLTNGKPVVKSVHSNIELLELLSLAGSIEKSSEHVIAKGIVEYAKEHNAPLKEMSEVKVKTGFGISAKTDYQGAKEVIKVGNSEFFNPINALEIQENGILVFVGRVISEKEDELLGAFVLEDLPKKGVKEHIAQIKKLGINTFLLSGDNRENVKKCALELGIDGYISNAKPQDKLNKIKELKEKGQIVMMVGDGLNDAPSLAMSDVAVVMAKGSDVSVQAADIVSFNNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLACGVLYKANIMLSPAIAGLAMSLSSVSVVLNSQRLRNFKIKDH
What is the function of this protein?
Probably involved in copper export.
What are the official names of this protein?
Copper-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRP36_EMENI
Sequence: MAISDLLNRRVRAAPDEDEEVYSDESASGSEPPSDEGSSDESGSESGRDSLNGSDNDFDSESQNSEASDSISEDEDDDGDVKSSLNNISFGALAKAQASFAPQTKRRTKNLKDNEGTTASPLDDIRAKIQEAREQKRKASLASKDSSAKSRVDKPPPRTSKHAPTVQSSKYAVSRKRTIIEPPSVPKSRDPRFDPTIVGGRGGSGSSAPSDAYAFLDDYRAAELRALKEQLAKTKDVRRREALQREIRSMTDRLRTIENHKREKEILSEHKKREKQLIREGKKATPYFLKKSDIKKQALLKKYEGMKSKDRAKALERRRKKAAAKERKEMPMERRGLGGDSDAAPSKRRRMA
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein rrp36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GSTT1_MOUSE
Sequence: MVLELYLDLLSQPCRAIYIFAKKNNIPFQMHTVELRKGEHLSDAFARVNPMKRVPAMMDGGFTLCESVAILLYLAHKYKVPDHWYPQDLQARARVDEYLAWQHTGLRRSCLRALWHKVMFPVFLGEQIPPETLAATLAELDVNLQVLEDKFLQDKDFLVGPHISLADLVAITELMHPVGGGCPVFEGHPRLAAWYQRVEAAVGKDLFREAHEVILKVKDCPPADLIIKQKLMPRVLAMIQ
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Also binds steroids, bilirubin, carcinogens and numerous organic anions.  Has dichloromethane dehalogenase activity.
What are the official names of this protein?
Glutathione S-transferase theta-1, GST class-theta-1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Theta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MARC_SHIBS
Sequence: MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAPPLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTYH
What are the official names of this protein?
UPF0056 inner membrane protein MarC.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KBTBD_MOUSE
Sequence: MPPGPEVPVQVWVDGQLFQAEQSLLVEHCGFFRGLFRSGMREARAAEVRLGALSASGFRTALRVLRGERPALAAEDELLQAVECAAFLQAPALARFLEHSVTSDNCSLLCDAAAAFGLRDVLHSAALFIRDGSHELVAQLELPEARAYVAALRPSTYVAVSTHTPTPGFLEDASRTMCFLDEEEDAWRTLAALPLEASTLLAGVATLGNKLYIVGGVCGASKEVVELGFCYDPEGGTWCEFPSPHQPRYDMALAGFEGRLYAIGGEFQRTPMSSVECYDPATGCWSFVADLPQPATGVPCAQARGRLFVCLWRPADITAVVEYVVQMDKWLPVAELCRSQSYGHFMVAHRDSLYVVRNGPSDDFLHCAIDCLNLVTGQWTSLPGQFVNSKGALFTSVVRGDTVYTVNRVSTLVYAIEDGTWRLLREKAGFPRPGSLQTFLLRLPPGTTGPVATALPEL
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein 13.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_PELSU
Sequence: MNLNRWLFSTNHKDIGTLYLIFGAWAGMIGTALSLLIRTELNQPGNLLGSDQTYNVIVTAHAFVMIFFMVMPVMIGGFGNWLVPLMIGAPDMAFPRLNNMSFWLLPPSLLLMLASSAIEAGAGTGWTVYPPLASNLAHAGASVDLAIFSLHLAGASSILGAINFITTVINMKTPNMSFLDMPLFVWSVLITAILLLLSLPVLAAGITMLLTDRNLNTTFFDPSGGGDPILYQHLFWFFGHPEVYILILPGFGIISHIVAYYSTKKEPFGYIGMVWAMTSIGFLGFIVWAHHMFTVGMNVNTRAYFTSATMIIAIPTGVKVFNWLATIHGGLIKWEAPMLWAFGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFTHWFTLFTGYPLHSTWTKIHFTTMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYTLWNSISSMGSMISLTAVVMMTFIIWEAMSSKRSTTTTEQMSTNVEWTYLCPPPNHTHVEATHLIRP
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYB_POMNI
Sequence: LTGLFLAMHYTSDIATAFSSVAHICRDVNYGWLIRNIHANGASFFFICIYLHIGRGLYYGSYLYKETWNVGVVLLLLVMMTAFVG
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HSLO_ALKOO
Sequence: MKNTVIRGTAASNQIRVFVANTTEMVAKAQELQMATPVAIAALGRTLTATSMMGLMSKSEKEKITVNINGGGPLGPIVVVGNSKGIVKGYVSHPHVEGSNLYPGKLDVGSAVGTDGTITVVKDLGLKEPYIGTYPLSTGEIAEDFAAYFAFSEQQPSGIALGVLVDVDYTIKAAGGYIIQVLPNIEEETLTKLESKLSTLEPITSIIDRIQDPEEILNHILGEFEPVILETYDVDFVCDCSEERLEQVLISIGEKELTEIIEEDKQAELVCHFCNKKYHFDEEHLNKLRSEILNKNNNI
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCT4_ORYSJ
Sequence: MATVDVLTSEVVVPAGETPAGAVWLSNLDLAARRGYTPTVFFYRHNGEPGFFAADAMRDSLARALVAFYPVAGRLGLDGDGRVQVDCTGEGVVFATARSGHYALDDLMGEFVPCDEMRDLFVPAAPAAASCCPRGGALLLVQVTYLRCGGVVLGMALHHSIADGRSAAHFVETWASIARGAPAADAPVPPCFDHRLLAARPARAVLYDHPEYKPEPAPPARAATASTYASAIITLTKQQVGALRAACAGASTFRAVVALVWQCACRARALPPEAETRLHSMIDTRQRLSPPLPPGYFGNAVIRTSTAATAGEVVSSPVGHAARRARAATSQGEDYARSVVDYLEGVDAMNLPRSGVSRADLRAISWLGMSLADADFGWGSPAFMGPAIMYYSGFVYVMNAPGKDGAVALALSLEPESMPEFRKVFADEVARLA
What is the function of this protein?
Hydroxycinnamoyl transferase that catalyzes in vitro the transfer of an acyl from p-coumaryol-CoA to glycerol or shikimate, to produce 2-O-p-coumaroyl glyceride or coumaroyl shikimate, respectively.  Quercetin, glutarate, or malate do not serve as acyl acceptors in vitro.  Can use feruloyl-CoA and caffeoyl-CoA as acyl donors.
What are the official names of this protein?
Hydroxycinnamoyltransferase 4, OsHCT4, BAHD-like hydroxycinnamoyl transferase HCT4, Glycerol hydroxycinnamoyl transferase.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: GHOT_ECOL6
Sequence: MALFSKILIFYVIGVNISFVIIWFISHEKTHIRLLSAFLVGITWPMSLPVALLFSLF
What is the function of this protein?
Toxic component of a type V toxin-antitoxin (TA) system.  Causes membrane damage when induced by MqsR, slowing cell growth and leading to the formation of dormant persister cells; involved with GhoS, its antitoxin, in reducing cell growth during antibacterial stress.  Its toxic effects are neutralized by GhoS, which digests ghoT transcripts in a sequence-specific manner.
What are the official names of this protein?
Toxin GhoT.
What is the protein family that this protein belongs to?
Belongs to the GhoT/OrtT toxin family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: URED_PROM2
Sequence: MIKTNWEGNCFLNFFNNKSSLENVDKTIFKSKSTSPYKLLKSTHDQEGRCILPVLHTAGGLVGGDLLEFEVNLEKNSKVLLTTSSAQKVYGSVGISKVNPKGTFSKQNNLIKILDNSHLEYLPQETIIFANGLYEQKFKVFISETSSFLFTDLIRLGRSSSGESIESGVFRSKLEIVRNNDLYDDWEYVDQIELSKASYVAKSGMDYMPVFGSLIWICEKDFSKSNINNLVGNIKKIFNETENNLSIGILENGISVRFLGSSSQDARKCFFCIWKQIRSVCGFCEPKYQGVWPLQDPMNY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPB30_MYCTU
Sequence: MALSIKHPEADRLARALAARTGETLTEAVVTALRERLARETGRARVVPLRDELAAIRHRCAALPVVDNRSAEAILGYDERGLPA
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Upon expression in M. smegmatis neutralizes the effect of cognate toxin VapC30.
What are the official names of this protein?
Antitoxin VapB30.
Protein: SURA_XANC5
Sequence: MTKPFSVVLASLLAITSTVSPLASAQQSQPLDRIAAIVDEDVVLQSELDRAVRNVKSQYAGRENQLPPDDVLQRQVLERLVLVKLQVSRADGNGIRVSDEELNRAIASIAQQNGTTVDGLRQKLAADGMGYADFRASVRDEIIVQRLRQSFAQSRISVSEGEVDTALAQQAATGSQYHLAHILIGLPEGATAEQIATGQKKVDGVKALIDKGELDFSAAAVRYSDSPNALEGGDLGWRSLDEIPNAFAQLIRDMQPGQVAGPLRGPSGFQLLKLVEMRDANAGGEKKMVTEYHARHILVRIGENQTEAQAKAKIDTIRARIVGGADFQATAKESSEDTNSRGQGGDLGWFPADAFGPDFGKQVESLTDGAVSEPFRTQAGWHIVQRVGSRQTDVSAENQRAQVRETIGRRKLEEEYNRYLQELRGEAYVSYRTGDRADDNATAAPAKSADPAAPSPPPAKPTR
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: RLMM_LARHH
Sequence: MSVVFLLQTRPGFERDAQQEARTVALERRGLELKPVETGEGFVLLQSDAPLTPFGWRDLAFSRTLSRVIADIQLGDRDRLTPILDVVGQKAMTFASIWLEWPDTNDGKAMSGFARKFQPLLEEKLATAGRLGQDASTRLQLFFPSKSRVLVSVSEPQWGAPWPLGILRLRMPTDAPSRSTLKLAEAFEVFLGEQGQQDKLKPGMTAVDLGAAPGGWTWQLLRRGIKVYAVDNGPMKGSCDGHPLVKHLRQDGFRFRPPHPVDWLVCDMVERPGRVAELMADWLAEGAARQAVFNLKLPMKKRAEALSDALERIEARMLAAGLAYTLQVKQLYHDREEVTVYLARPAATGRRRR
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_PROMT
Sequence: MAKKGTRIVVTLECTESRTVPSSKKRSAGVSRYTTEKNRRNTTERLELKKFCPELNKMTIHREIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TSAC_ENT38
Sequence: MNNNYPLGSIAQAVDVLKNEEVIAYPTEAVFGVGCDPDSETAVTRLLELKQRPVEKGLILIAANFEQLKPYIDDSMLTEQQRNTIFSAWPGPVTFVFPALPSTPSWLTGRFDSLAVRVTDHPLVVELCETFGKPLVSTSANLTGLPPCRTSQEVLAQFGDGFPVVVGETGGRLNPSEIRDALTGERFRQG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_RICBR
Sequence: MKKILGIESSCDDTSVSIITEDREILSNIVISQNTEHADYKGVVPEIAARSHLANLEKAMKQALLESNTSLDEITAIAATSGPGLIGGVIVGSMFAKSLSSVLNKPFIAVNHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDDAVGEAFDKVAKMLDLPFPGGPKIEKRAKLGDPYKYKFPKPIINSGDCNMSFSGLKTAVRTLIMSLQEINDTIINDIAASFQFTIGEILSSKILEAIKVYEQITNDFNRNIVIAGGVAANKYLQELLSNCTKIHGYQLIYPPTTLCTDNAAMIAYAGLERYNNGLFTPLNFCPKARWSLEEI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCD_PIG
Sequence: MPAHLLQEEISSSYTTTTTITAPSSRVLQNGGGKLEKTPQYVEEDIRPEMKDDIYDPTYQDKEGPRPKLEYVWRNIILMSLLHLGALYGIILIPTCKIYTLLWAFAYYLLSAVGVTAGAHRLWSHRTYKARLPLRVFLIIANTMAFQNDVYEWARDHRAHHKFSETDADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGLLNMSDLKAEKLVMFQRRYYKPGILLMCFILPTIVPWYCWGEAFPQSLFVATFLRYAIVLNATWLVNSAAHLYGYRPYDKTISPRENILVSLGAVGEGFHNYHHTFPYDYSASEYRWHINLTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDESYKSG
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.  Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity).  Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids.  Plays an important role in lipid biosynthesis.  Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity).  Plays an important role in body energy homeostasis (By similarity).  Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).
What are the official names of this protein?
Stearoyl-CoA desaturase, Acyl-CoA desaturase, Delta(9)-desaturase, Delta-9 desaturase, Fatty acid desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MATK_EURFE
Sequence: MDKLQYELQGYLEIDRYRKQRFLYPLLFREYIYALAHDHGLNSSIFYEPTENLGYDNDNKSSSLIVKRLITRLHQQNHLTISVNDSRFVGPNRSFYSQTIPEGFAGIMEIPFSVRLVCSLERERIAKYQNLRSIHSIFPFLEDKLSHLYYVSDILIPYPIHLEILLQTLRTRIRDAPSLHLLRCFLHEHHNWNSLITSNKSISIFSKENQRLFLFLYNSHVYECESVLVFLRKQSSYLRSISSLAFLERTHFYGKIKHLVVTPRNDSQRTLPLWFFKEPLMHYVRYQGKSIMASRCTNLLMXKWKYYLVNFWQCHFHLWSQPGRIHINELSNHSFYFLGYLSGVRLTPWVIRSQMLENSFMIDTAIKRFDTIVPIFPLIGSLVKAKFCNVSGYPISKSVWADSSDSDIIGRFGWICRNLSHYHSGSSKKHSLCRIKYILRLSCARTLARKHKSTVRAICKRLGPKLLEEFLTEEHEIVSFILRRTRLRNERIWYLDIIRINGLVPHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARND_SALEP
Sequence: MTKVGLRIDVDTLRGTREGVPRLLATLHRHGVQASFFFSVGPDNMGRHLWRLIRPRFLWKMLRSNAASLYGWDILLAGTAWPGKNIGNANAGIIRETATYHETGLHAWDHHAWQTHSGHWSIRQLEEDIARGITALEAIIGKPVTCSAAAGWRADGRVVRAKEPFNLRYNSDCRGTTLFRPLLMPGQTGTPQIPVTLPTWDEVIGPAVQAQSFNTWIISRMLQDKGTPVYTIHAEVEGIVHQPLFEDLLVRARDAGITFCPLGELLPTSPESLPLGQIVRGHIPGREGWLGCQQAASAS
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: KLHDB_CULQU
Sequence: MGDVLISDRPPSPARLSHTSEKHPRVTLTELNVLRRHRELCDVVINVSGRKIFAHRVILSACSPYFRAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTSHIVVEESNVQTLLPAACLLQLAEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMAWLKYNVAERRQHLAQVLQHVRMPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPETADWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGYLYAIGGSDGQCPLNTVERYDPRQNKWCAVSPMSTRRKHLGCAVFNNFIYAVGGRDDCMELSSAERYNPHTNSWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGTAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAPQTENYMW
What is the function of this protein?
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  May have a role in synapse differentiation and growth (By similarity).
What are the official names of this protein?
Kelch-like protein diablo.
Protein: RR12_CYAM1
Sequence: MPTLQQLIRFGRQQVMVRPKSAALKRCPQRRGVCVKVYTTTPKKPNSALRKVARVKLTSGYEVTAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIIRGALDTAGVKNRVRSRSKYGVKKA
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MTDB_METEA
Sequence: MARSILHMLTPLKHMSPFDVNMAIDAGFETLIPYTGVDLTDVVSLTQDSIFSRAPQDGVRTGIFIGGKNAELALDMVDRAKKAFVPPFVNHVFADPAGSFTTGAAMVAEVNRALKARFSTDLKGKRIVIFGGAGVVAYVAAVIGALEGAQTVLVGHDGEERVSKIAFTMKWRFGIDVGAVDGTLPEARRAAITDADVILSAGPAGVSILTAEDLESAPKLLVASDVNAVPPAGIAGIDVNAVDVPLPTGKGVGIGALAVGNVKYQTQCRMFRKMLEAQEPLCLDFRDAYKLAVEIAG
What is the function of this protein?
Catalyzes the dehydrogenation of methylene-H(4)MPT.
What are the official names of this protein?
NAD(P)-dependent methylenetetrahydromethanopterin dehydrogenase.
What is the protein family that this protein belongs to?
To M.extorquens MtdA.
What are the subcellular locations of this protein?
Cytoplasm.