PharMolix/UniProtQA huggingface dataset:
Protein: MTNW_BACAH
Sequence: MSGIIATYLIHDDSHNLEKKAEQIALGLTIGSWTHLPHLLQEQLKQHKGNVIHVEELAEHEHTNSYLRKKVKRGIIKIEYPLLNFSPDLPAILTTTFGKLSLDGEVKLIDLTFSDELKKHFPGPKFGIDGIRNLLQVHDRPLLMSIFKGMIGRNIGYLKTQLRDQAIGGVDIVKDDEILFENALTPLTKRIVSGKEVLQSVYETYGHKTLYAVNVTGRTFDLKENAKRAVQAGADILLFNVFAYGLDVLQSLAEDDEIPVPIMAHPAVSGAYSASKLYGISSPLLLGKLLRYAGADFSLFPSPYGSVALEKEEALAISKYLTEDDVFFKKSFSVPSAGIHPGFVPFIIRDFGKDVVINAGGGIHGHPNGAQGGGKAFRTAIDATLQNKPLHEVDDINLHSALQIWGNPSHEVKL
What is the function of this protein?
Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
What are the official names of this protein?
2,3-diketo-5-methylthiopentyl-1-phosphate enolase, DK-MTP-1-P enolase, RuBisCO-like protein, RLP.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type IV subfamily.
Protein: RXL7_STAAN
Sequence: MSKEKVARFNKQHFVVGLKETLKALKKDQVTSLIIAEDVEVYLMTRVLSQINQKNIPVSFFKSKHALGKHVGINVNATIVALIK
What are the official names of this protein?
Putative ribosomal protein L7Ae-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: TBPL1_BOVIN
Sequence: MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL
What is the function of this protein?
Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes.  Seems to also mediate the transcription of NF1.  Does not bind the TATA box (By similarity).
What are the official names of this protein?
TATA box-binding protein-like 1, TBP-like 1, TATA box-binding protein-related factor 2, TBP-related factor 2, TBP-like factor, TBP-related protein.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MTRD_METMA
Sequence: MIDAILGNILWMVFIIIGGVLISWGVHFVPVGGAPAAMAQATGVGTGTVQLATGAGLTGLVSAGFMMNVTDNFPLIVASGAVGAMIMIAVTMIVGTWIYVYGVGCVPSSAKVKVDPITKYRQDLYVSQGTEGHGIPTVSFVSGVIGAALGGIGGSLIYYSLIEVGVSVGLERVGVTSAVTGNSLVAVAAIFAIGIFLVNAVIPSYNIGGTIEGFHDPKFKKWPKAVISSVVASILCAIVAVIAIAQLGGI
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit D, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit D.
What is the protein family that this protein belongs to?
Belongs to the MtrD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YHBO_ECOLI
Sequence: MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals (PubMed:26774339, PubMed:28596309).  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Is able to repair glycated serum albumin, collagen, glyceraldehyde-3-phosphate dehydrogenase, and fructose biphosphate aldolase.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of advanced glycation endproducts (AGE) that cause irreversible damage (PubMed:26774339).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair (PubMed:28596309).  In vitro, prevents acrylamide formation in asparagine/glyoxal and asparagine/sugar mixtures at 55 degrees Celsius, likely by degrading asparagine/glyoxal Maillard adducts formed at high temperatures (PubMed:27530919).  Also displays an apparent glyoxalase activity that in fact reflects its deglycase activity (PubMed:26774339, PubMed:26678554).  Is a general stress protein; is required for the protection of bacterial cells against many environmental stresses, including oxidative, thermal, osmotic, UV, and pH stresses (PubMed:17933887).  And plays an important role in protection against electrophile/carbonyl stress (PubMed:26774339).
What are the official names of this protein?
Protein/nucleic acid deglycase 2, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_STAAS
Sequence: MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFDVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVDGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAGTGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQTSDVYRKIRNTLRFMLGNINDFNPDTDSITESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACB2_BOVIN
Sequence: MAATLQRIERLSSRVIRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPSIPEYISCLKQALTEFNTAIQEIIVTHWHRDHTGGIGDICKSINNDTTYCVKKLPRNPERKEIIGNGEQQYVYVKDGDIIKTEGATLRVVYTPGHTDDHMALVLEEENALFSGDCILGEGTTVFEDLYDYMNSLKELLKIKAKVIYPGHGPVIHNAEAKILQYISHRNIREQQILTVFHENFEKSFTAMELVKSIYKDTPEHLHKMAQHNVLLHLKKLEKEGKIVSNTDPEKKWKAHL
What is the function of this protein?
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA.  The cleavage product contains a free 3' -OH group.  Has no activity with double-stranded RNA or DNA.  Required for normal mitochondrial function and cell viability.
What are the official names of this protein?
Endoribonuclease LACTB2, Beta-lactamase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MGSA_BACC7
Sequence: MKIALIAHDKKKNDMVSFAYAYKPIFEQHELFATGTTGLRIMEATGLVVTRYQSGPLGGDQEIGAMIAKNDLDMVIFFRDPLTAQPHEPDVNALLRLCDVYAIPLATNMASAEMLMHALERGDLDYRKLRK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: OPGG_ECO27
Sequence: MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATAVKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAYKFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPSAWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDEDKLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTSIGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SP4_MOUSE
Sequence: MSDQKKEEEEEAAAAMATEGGKTSEPENNNKKPKTSGSQDSHPSPLALLAATCSKIGTPGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQPASSSSSSSSSNNGSSSPTKTKSGNPSTPNQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQINPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVTAGGGTGQVGQPTTTTDSGTSNGNQLVSTPTTSTAPASTMPESPSSSTTCTTTASTTLTSSDTLVSSADTGQYASTSASSSERTIEEPQTPAATESEAQSSSQLQSNGIQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQQTSDAEVQPGKRLRRVACSCPNCREGEGRGSSEPGKKKQHVCHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF
What is the function of this protein?
Binds to GT and GC boxes promoters elements.  Probable transcriptional activator.  Required for normal male reproductive behavior.
What are the official names of this protein?
Transcription factor Sp4.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACUK_PYRTR
Sequence: MTTPDAEDASPSPEYRSDQDDDMAAEQTTDRQSGDASPTQKPANGKPNAKDPLRPRRKKARRACFACQRAHLTCGDERPCGRCIKRGLQDHCMDGVRKKAKYLHDAPDGSLMPGVGGHYPYMNGNRPTPLPAQDTHTVSVSPQSNMYNQAQPPAAFYPPNSIPGQLPVTQDTRAFSNQQSPISPPFTQAHHASVQNAGAPSTMSQGQQGMQQFGPLFDPSDPALFNFDISSLNFGNHYGALEFGMLGHMSSGAVETPHDNNLMNNMSGSVNMYNQQVPSGYPDQNNAAAMAFGPNGLPGSEWQETQSRQGSMHVHTPNNTSGSGSHDHHPHRNDSLNGPHAFAIGQGPATHSTASPASTDASTYEGDNPLSTAAFFANANRPHAQRSPLVSRPQQENRPPTTALQSIHANGIRKRQRDTKSVYQGITKPYDYVKGYHRLYQLIDKKYSRPWVAKAQQYLQNYRPVLLQVREELNRDDLIHQEMGLQRHLMTLQEHFAEVGTPFLICRRSGEIVGINKEFTILTGWKRDVLLGHEPNLNVNLGTNRESSESDTSTQNTTPNLSAQDSEGATPSVNIIELMDARSALEFLQHFSELCYQDPRGYASQRVNMLRYQTKADVDRIHNMKNASSGDAKLDPLVKMEGGAVHQGESAMQRLGAKSGMVDCMIWWHIKRDIFDMPVLVCMSVMPVLDKGLP
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis PTRG_06536.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1051_BACCZ
Sequence: MVHMHITAWALGLILFFVAYSLYSAGRKGKGVHMGLRLMYIIIIVTGVWLYLDQTIVDKSYHMWYGLKMLAGILVIAGMEMVLVKMSKNKATGAFWGLFIIALVAVFYLGLKLPIGWQVF
What are the official names of this protein?
UPF0344 protein BCE33L1051.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL21_MAGSA
Sequence: MFAVIQTGGKQYKVASGDVIRVEKLAGEAGAEVVLDQVLMVGDKIGVPVVAGASVKATVVAQARGEKIIVFKKRRRQNSRRKNGHRQDLTILRITDISAG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: STE11_PNECA
Sequence: MLGRDIESDWIGNYWGRDHSLALNTFSKMSIEKEGVLYQKDFFVPYDGLVEELPEHSIEIPEIMGQDLLNDRLNSVEDVQSSYYGRLMPGLNIDLSMPTFPVSNELPVRLSSPIQMNLSTSMPNPTIEQLHSKTKSYVSQNPVNMVGSLSGSPPTDCHSPGGNSNTCGTLKTRALSLSPVSSDTAAKKKSPSRSGSSSSGIKRPLNSFMLYRRDKQSSIPTNNHQSISRIIGEMWKRETIEEKERYAEMAQRERERHAKEYPDYKFLPRKKKDRSTSGKSPRRRKTFDPSLEQDESKVLRMMLNQISHKKSQSDAEKFKLDQYSWLLSEEGNYDSQKGAFDIICQANTNSSQTGLPHSNQPSEISFIPGIYTAPNSVPLPIFPVKNKVEKVDTHNSLDGYLHTFDNLSDYEFRSLINNHSTPSVNDSRLGTSFNKSCTDSPQSISIYDDIKNLDIFSEKKETPNVSLVPTFDSTIFQDDSAYGYDNFTGIWDDPSYRLPVF
What are the official names of this protein?
HMG-box protein STE11.
What are the subcellular locations of this protein?
Nucleus.
Protein: PA2_URTCR
Sequence: MKNNIILVILLGISVFVDCLPLNDQEEDKSLNAQESEVSAVQKRDILQFSGMIRCATGRSAWKYFNYGNWCGWGGSGTAVDGVDSCCRSHDWCYKRHDSCYPKIIPYIASTSGSHPSCSITCHSANNRCQRDVCNCDKVAAECFARNTYHPNNKH
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 A2-actitoxin-Ucs2a, A2-AITX-Ucs2a, Phosphatidylcholine 2-acylhydrolase, UcPLA2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RS13_EHRRG
Sequence: MARIAGVNIPTNKRVVIALTYIYGIGISLANKICESCNIDHNIRVVNLSDDEIIRIRNFIRENYVVEGDLRKEVSMNIKFLTDIGCYRGLRHRRGLPVRGQRTHTNAKTRKGRSRLPVAAKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: EF2_METS5
Sequence: MPKYKTSEQVLSLMKDRTRVRNIGIIAHVDHGKTTTSDQLLAASGIISPKVAGEALALDYLSVEQQRGITVKAANVSLYHEVEGKGYVINLIDTPGHVDFSGRVTRSLRVLDGSIVVVDSVEGVMTQTETVLRQSLEERVRPILFVNKVDRLVKELKLGPQEMMQKLMDIIKEVNNLINIYAEPELKEKWAINPTLGNVVFGSAKDRWGFSIPMAQKKGINMKHVIDAYSTTDKTKINELASQVPINEALLDAVIKFVPNPVDAQKYRIPKIWKGDLDNELAKSMLNADPNGPVVMMITDMKVDPHAGLVATGRVFSGTIRPGSEVWLVNAKAPQKVLQVSIYMGQFRELADEIPAGNIAAVLGLERARSGETLIDIRYKDLQGSFEKLHYVSEPVVTIAVEPKNPKDLTKMIDALRKLSIEDPNLVVKINEETGEYLLSGMGFLHVEVSLQLLKDNYGVDVVTTPPIVVYRESVRNKSQVFEGKSPNKHNKFYISVEPLNDKTIELISNGTIKEDMDSKEMAKILRDQADWDYDEAKKIIAIDENVNVLIDATSGVQHLREIMDTMLQGYRLAMREGPLAHEPIRGVKVILHDATIHEDPAHRGPAQIYPAVRNAIFAAMLMSKPTLLEPLQKLDIRVPMEFVGNVTAVLSRKRGKVLNMTQSGSVARILAEIPVSESYELASDLRGSTGGRAFWGTEFSKWAPVPDSILTDVILKIRERKGLPKELPKVEDFLS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_STRS2
Sequence: MTKEKLILAYSGGLDTSVAIAWLKKDYDVIAVCMDVGEGKNLEFIHDKALSIGAIESHVLDVKEEFAQEYVLPALQAHAYYEQKYPLVSALSRPLISKKLVEMAHKTGATTIAHGCTGKGNDQVRFEVAIAALDPSLKVVAPVREWKWAREEEIIFAKENGVPVPADLDSPYSVDQNLWGRANECGVLENPWNEAPEDTFGITTSPENAPDTPEYVDIEFKAGIPVAVNGEKLSLANLIQRLNVIAGKHGVGRIDHVENRLVGIKSREIYECPGAITLLTAHKEIEDLTLVREVSHFKPIVSNELSNLIYNGLWFNPATDALKAYLAQTQAVVNGTAKVKLYKGSAKVVARKSPNSLYDEDLATYTSADTFDQDAAVGFIKLWGLPTKVNAEIHKKS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED4_CAEEL
Sequence: MAETDERSLRDLLLESADDLEHIVKMIVDTLINRDKSVMLKNGETVTNIIKLFDSKQDSIKTLLKRVPEFQEREQLIRTLEAHVEKRDEVIQQLETNLKSCEVALTRSCFHANQKLKQMKEAELRPVNSEMLIKLAHQISKHNSVSAPLTWQMGDPSRPFPQEHEFRAGHLLNSKVQSTGPQLLPGKNVAQRPLITSPSASSSNGGTAPIRTVGTPLINSAPTGDFSPRTGFGTDEPPPIQQQVLRGATPNEKQWQNPGVSGATSTQSPYNRVSQSPSSSPNVKLKITGLPNRPGGIDQVQDVRDVEQMSSDSSNSSDSSDDEGASKKTGSSNK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 4, Mediator complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCOR_CAPAN
Sequence: MAGQTVIVSGLNPAAILQSTIGGAPPSTAAAAAENGDTTRKVVPLSKDALQDFMVSIITQKLQGEKKPFYVLDLGEVVSLMDQWNVALPNVRPFYAVKCNPEPSFLSMLAAMGSNFVCASRAEIEYVLSLGISPERIVFANPCKPESDIIFAEKVGVNLTTYDSEDEVYKIKKHHPKCELLLRIKPMNDGNARCPMGPKYGALPEEIEPLLRIAQASRLTVSGVSFHIGSGDADSNAYLGAIAAAKQVFETAAKFGMSKMNVLDIGGGFTSGHQFTTAATAVKSALQQHFSNEPELTIIAEPGRFFAETAFTLATTIIGKRVRGDLREYWINDGLYGSMNCVLYDHATVTATPLACMSNRVNLNCSGSKMFPSTIFGPTCDALDTVLRDYHVPELQVNDWVIFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS
What is the function of this protein?
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
What are the official names of this protein?
Ornithine decarboxylase, ODC, CaODC1, CapODC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
Protein: PANB1_BURL3
Sequence: MSAHTRTTRKTVTAIRSTKGIGSLVSLTAYSAPMAKLVDEVADVIIVGDSVGMVLYGMPDTLRVTLDMMIAHGAAVVRGAAQACVVVDLPFSTYQESPAQAYRSAARLLAETGAQGVKLEGGTEMADAIRFLTERGIPVMAHVGLMPQQANATGGFRAQGMDPRSAAQVFDAACSAEQAGAFSVVIEGTAEALARHITETLTIPTIGIGASPACDGQVLVTEDMIGAFDAYTPRFVKRYADANAVMRDAIRQYAHDVRQGVFPEPAHCFGYGKPLQLVGAADAAA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 1, Ketopantoate hydroxymethyltransferase 1, KPHMT 1.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_RHIL3
Sequence: MQWQDHAIILGVKRHGETSVIAEVMTRDRGRHLGLVRSGRSRAMQPVLQAGNAVEVIWRARLDEHLGEFRVEPVTLRAARLMETATAVYGVQAMGALLRLLPERDPHPHLFDALEVILDHLHNPADAGELFVRFELAVLNDLGFGLDLAECAATGARSDLVYVSPKSGRAVSRAAGAPWADKMLLLPPFLSIEGNHAADFDSLSAAFRLTGFFLHRHVYEPRGIEAVAARDGFVQAALKALNPTLRTLSGPNGVSA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: Y056_LEPBP
Sequence: MSGHSKWATIRRKKGAIDAKRGAIFTRIAKEISVAAKEGGGDQEGNPRLRLAVTKAKAANMPKDNIERAIKKGTGGLEGMVYEECLYECYAPGGVAIMVDVLTDKKSRTTPEIKSILTKLGGSLANAGAVSRLFERKGQLTLKADQISEEALFDLALGAGAEDIQVNDGMYVVLTSPSEYEAVQSALSSKGLNMEESEIKYIPMTTVEVNEKETAEKVMKLIENLEANDDVQGVSSNFELGEGVELD
What are the official names of this protein?
Probable transcriptional regulatory protein LEPBI_I0056.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_AGARV
Sequence: MFDKLEDLIHHYEELMNLLSEPDVANDANRFKKLMKEQSDLAPIVETYKKYKECKQNIEDSLAILDEESDEEMRELAKEELKDSKEQVEELEKKLKILLLPKDPNDDKNVIVEIRAGAGGEEAALFAAEIYRMYVHYAENRGWKVETLDADETGIGGMKSVEFMVKGSGAYSILKYESGVHRVQRVPETESQGRIQTSTCSVAVMPEAEDVDVKIDDKDIRIDVMRASGNGGQCVNTTDSAVRLTHYPTGIVIYSQTEKSQIQNKEKAFALLRTKLYDMELQKKQDAEAEERRSQIGTGDRAEKIRTYNFPQGRVTDHRINLTLYKLDKILNGDIQEIIDACIAADQAKKLSNMEHDA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ST1C1_MOUSE
Sequence: MPLEKLKDLHLDEQNMQPETREVNGILMSKMMSENWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPPPLNSGLDLANKMPSPRTLKTHLPVQMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPDPGTLGEYIETFKAGKVLWGSWYDHVKGWWDVKDKHRILYLFYEDMKEDPKREIKKIVKFLEKDISEEVLNKIIHHTSFDVMKQNPMANYTTLPSSIMDHSISPFMRKGMPGDWKNYFTVAQSEDFDEDYRKKMAGSTITFRTEI
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters.  May be involved in the activation of carcinogenic hydroxylamines.  Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF).  Also shows activity towards cinnamyl alcohol at pH 6. 4 but not at pH 5. 5, and towards a number of phenolic odorants including eugenol, guaiacol and 2-naphthol.
What are the official names of this protein?
Sulfotransferase 1C1, ST1C1, Phenol sulfotransferase.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1400_FRATH
Sequence: MDHSVLNVLVCPICKANLYYDKENQVLVCKADKLAYPIRENIPVMLVEEAKKMTLEEVKKYG
What are the official names of this protein?
UPF0434 protein FTL_1400.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.