PharMolix/UniProtQA huggingface dataset:
Protein: TAF13_HUMAN
Sequence: MADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLVIEFITEMTHKAMSIGRQGRVQVEDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFDEANYGS
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473, PubMed:9695952).  TFIID recognizes and binds promoters via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473).  TAF13, together with TAF11 and TBP, play key roles during promoter binding by the TFIID and TFIIA transcription factor complexes (PubMed:33795473).
What are the official names of this protein?
Transcription initiation factor TFIID subunit 13, Transcription initiation factor TFIID 18 kDa subunit, TAF(II)18, TAFII-18, TAFII18.
What is the protein family that this protein belongs to?
Belongs to the TAF13 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUA_AZOC5
Sequence: MPRYKLTIEYDGTPFAGWQIQAELPTVQGVLAAAVKGFSGEEAHVAGAGRTDAGVHATGQVAHIHLARDWRPDQVRDAMTAHLRPHPVAVVAVERVADDFDARFSAVKRHYLYRIVNRRPDLALDRDRAWRVPQKLDASAMHVAAQRLLGKHDFTTFRAAECQAASPEKTLDQLDVMRSGDDIRIVTSARSFLHHQVRSMVGSLIRVGEGRWSADDLADALAARDRRRCGPMAPACGLYLAAVSYPEQIVETGAPDRI
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: VPR_HV1SC
Sequence: MEQAPEDQGPQREPYNEWTLELLRKLKSEAVRHFPRIWLHGLGQHIYETYGDTWAGVEAIIRILQQLLFIHFRIGCRHSRIGIIQQRRSRNGSSRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: RK20_AMBTC
Sequence: MTRVRRGYIARRRRTKIRLFASTFRGAHSRLTRTATQQKMRALVSIYRDRGRQKREFRRLWIARINAATHENGVSYSRLINDLYKRQLLLNRKIPAQIARYNLNSLYMISNEIIKEKRD
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GREA_JANSC
Sequence: MEKIPMTPKGLEAMNGELKQLKSVERPAIIKAIAEAREHGDLSENAEYHSAKEKQSFIEGRIKELEGSISLAQVIDPATLSGAIKFGATVDLVDEETEEEKTYMIVGEAEADIEKGLLNIKSPLARALIGKEEGDSVEVRTPGGAKGFEIVKISYV
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: SYS_LEIXX
Sequence: MIDPVLLREHPDVLRRSQEARGDSVQLVDEALQVDIERRAAITAFEELRAEQNAFGKRVAQAPKQEKKELVAQAQQLAGRVKEAQQVAAAAEARFESVLRKIGNPVVAGVPSGGEDDYAVLKEVGGIPAFGFEPRDHLALGELLGAIDMARGAKVSGARFSFLRGLGARLEIALMNLALDKALANGFVPLITPTLVKPEVMQGTGFLGEHSDEVYHLETDDLYLTGTSEVALAGYHADEILDVTEPLRYAGWSTCYRREAGSAGKDTRGIIRVHQFTKLEMFVYTLPEHAEAEHARLLAWQEEMMQALGLSYRVIDTAAGDLGSSAARKYDVEAWIPTQGRYRELTSTSNCGTFQARRLETRYRTESGKTAPVATLNGTLATTRWIVAILETHQREDGSVLVPETLRPYLGGLEILEPIGK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_BACCQ
Sequence: MKKRALVSVSDKTGVVEFVKGLLEQGIEVISTGGTKKLLEENGLQVIGISEVTGFPEIMDGRVKTLHPNIHGGLLAVRDNETHVAQMNELGMEPIDFVVVNLYPFKETIAKPDVTFADAIENIDIGGPTMIRSAAKNHKFVSVIVDPVDYDIVLAELKENGEVKEETKRKLAAKVFRHTAAYDALISNYLTEQMGEESPETLTVTFEKKQDLRYGENPHQKATFYKAPFAVTSSVAYAEQLHGKELSYNNINDADAALSIVKEFTEPAVVAVKHMNPCGVGVGTDIHEAYTRAYEADPVSIFGGIIAANREIDKATAEKLHEIFLEIIIAPSFSKEALEVLQSKKNLRLLTVNIEKATSASKKLTSVQGGLLVQEEDTLSLDESTISIPTKREPSEQEWKDLKLAWKVVKHVKSNAIVLAKDDMTIGVGAGQMNRVGSAKIAITQAGEKAQGSALASDAFFPMPDTLEEAAKAGITAIIQPGGSIRDEDSIKVADTYGIAMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: HIS5_BACAA
Sequence: MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRBP2_RAT
Sequence: MDENSELGGLETMETLTELGDELTLGDIDEMLQFVSNQVGEFSDLFSEQLCSSFPGGGGGSGSGGTSNNSSGRGTSGGAADPAVQRSFSQVPLSTFSPSSTSPQAPALQVKVSPTPPRATPVLQPRPQPQPQPPAQLQQQTVMITPTFSTAPQTRIIQQPLIYQNAATSFQVLQPQVQSLVTSSQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVATPQVQQVPVLVQPQIIKTDSLVLTTLKTDGSPVMAAVQNPALTALTAPIQTAALQVPTLVGSNGAILTTMPVMMGQEKVPIKQVPGGVKQLEPPKEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKSGVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDSDVDLKIDDFNQNVLLMSPPASDSGSQAGFSPYSIDSEPGSPLLDDAKVKDEPDSPPVALGMVDRSRILLCVLTFLGLSFNPLTSLLQWGGAHNPDQHPYSGSGRNVLSLESGSGGWFDWMMPTLLLWLLNGVIVLSVFVKLLVHGEPVIRPHSRSSVTFWRHRKQADLDLAKGDFAAAAANLQTCLSVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQRWRATPATAAGFEDEAKSSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKIPPSTLVEIHLTAAMGLKTRCGGKLGFLASYFLNRAQSLCGPEHSAVPDSLRWLCHPLGQKFFMERSWSIKSAAKDSLYCAQRNPADPIAQVHQAFCKHLLERAVEALVKPQAKKKAGDREEESCEFSSALEFLKLLHSFVDSVGFVASPFSSSSVLRSALGPDVVCRWWTSAITVAISWLQGDDAAVRSHFTEVERVPKALEVTESPLVKAVFYACRAMHASLSGKADGQQNSFCHCERASGHLWSSLNVSGTTSDPSLNHVVQLLTCDLLLSLRTTLWQKQASASQLLGETYHASGTELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRTTQNTKHGEVDTWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCSDCQQMIVKLGGGTAIAAS
What is the function of this protein?
Key transcription factor that regulates expression of genes involved in cholesterol biosynthesis.  Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3').  Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').  Regulates transcription of genes related to cholesterol synthesis pathway.
What are the official names of this protein?
Sterol regulatory element-binding protein 2, SREBP-2, Sterol regulatory element-binding transcription factor 2.
What is the protein family that this protein belongs to?
Belongs to the SREBP family.
What are the subcellular locations of this protein?
[Sterol regulatory element-binding protein 2]: Endoplasmic reticulum membrane; Multi- pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=At high sterol concentrations, the SCAP-SREBP is retained in the endoplasmic reticulum. Low sterol concentrations promote recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi, where it is processed. SUBCELLULAR LOCATION: [Processed sterol regulatory element-binding protein 2]: Nucleus. Note=Transported into the nucleus with the help of importin-beta. Dimerization of the bHLH domain is a prerequisite for importin beta-dependent nuclear import.
Protein: RRF_ACTP7
Sequence: MINEIKKDTQDRMEKSLEALKSHISKIRTGRAQPSLLDGIQVEYYGSATPLRQLANVVAEDARTLAVNVFDRSLISAVEKAILTSDLGLNPSSAGATIRVPLPPLTEERRRDLIKIVKGEGEQGKIAIRNVRRDANDQIKALLKDKEISEDEERKAQDEIQKITDGYVKKVDEVLAAKEKELLDF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_METFK
Sequence: MTSLKNDVFLRALQRQRTPYTPVWMMRQAGRYLPEYRETRKKAGSFMDLCKNTDLATEVTLQPLDRFPLDAAILFSDILTIPDAMGLGLYFEEGEGPKFERTLREESDIRKLAVPDIGSELRYVTDAVSQIRRALDGRVPLIGFSGSPWTLATYMVEGRGGTDFLTIKQMAYARPDLLHHILSVTAQAVTAYLNAQIAAGAQAVMIFDSWGGALSHYAYQEFSLQYMQQIVSGLTKESEGRVVPSIVFTKGGGLWLESQAETGADALGLDWTISLGEARKRVGSKVALQGNMDPAILLSTPEAVEKEVARILADYGIGNGHVFNLGHGITQFTPHENAEAMIKAVHAISSKYHL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCC2_MOUSE
Sequence: MKRCKSDELQQQQGEEDGAGMEDAACLLPGADLRHGEASSANSAGGPTSDAGAAVAPNPGPRSKPPDLKKIQQLSEGSMFGHGLKHLFHSRRRSREREHQASQEAQQQQQQQGLSDQDSPDEKERSPEMHRVSYAVSLHDLPARPTAFNRVLQQIRSRPSIKRGASLHSSGGSGGRRAKSSSLEPQRGSPHLLRKAPQDSSLAAILHQHQGRPRSSSTTDTALLLADGSSAYLLAEEAESIGDKGDKGDLVALSLPSGPGHGDSDGPISLDVPDGAPDPQRTKAAIEHLHQKILKITEQIKIEQEARDDNVAEYLKLANNADKQQVSRIKQVFEKKNQKSAQTIAQLHKKLEHYRRRLKEIEQNGPSRQPKDVLRDMQQGLKDVGANMRAGISGFGGGVVEGVKGSLSGLSQATHTAVVSKPREFASLIRNKFGSADNIAHLKDPMEDGPPEEAARALSGSATLVSSPKYGSDDECSSASASSAGAGSNSGAGPGGALGSPRSNTLYGAPGNLDTLLEELREIKEGQSHLEDSMEDLKTQLQRDYTYMTQCLQEERYRYERLEEQLNDLTELHQNEMTNLKQELASMEEKVAYQSYERARDIQEAVESCLTRVTKLELQQQQQQVVQLEGVENANARALLGKFINVILALMAVLLVFVSTIANFITPLMKTRLRITSTALLLLVLFLLWKHWASLTYLLEHVLLPS
What is the function of this protein?
May be involved in the regulation of the proteolytic processing of the amyloid precursor protein (APP) possibly also implicating APOE.
What are the official names of this protein?
Transmembrane and coiled-coil domains protein 2.
What is the protein family that this protein belongs to?
Belongs to the TEX28 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Concentrates in discrete patches along peripheral endoplasmic reticulum tubules.
Protein: NUOH_SALA4
Sequence: MSWITPDLIEILLSILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLSFAIVPVSPNWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTVSYEVFLGLSLMGVVAQAGSFNMTDIVNNQAHLWNVIPQFFGFVTFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTVSALMVTLFFGGWHGPFLPPFVWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKVCLPLTLINLLVTAAVILWQAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL15_COXB1
Sequence: MQLNDLKPAKGARHQKLRVGRGIGSGKGKTAGRGHKGQHSRAGGYHKVGFEGGQMPLQRRVPKFGFTSRKELISAEVRLGELNKISGDVVDLASLKAANIISRQIKRVKIFAAGKLEKPVTIRGLRVTKGVKAAIEAAGGKIE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: YR595_MIMIV
Sequence: MYKKILIILIIIIIVIISLIYLKNFILYQPHKDHPVKYCKFFHKLSKLTEPENIHHLYLKTPDNILLDTIVIRNTDTNKCIIYFHGNAGNIAMRYNIIKFLFNYASVIVFDYRSFGRSTGSFITMNQQDLSTDAETIWNYVIKNLHYNPNNISLFGESLGCSVAINLAVNISKNFDSKYYPHSLILNSPFYSLSEMVKSIFHKANLSQFGSVLSNLFREYQSDKLIPFMNQHTKIIIAHSHNDEIIPFEQGFKLYQLIANTHTNSKFIIINGSHNNPGLPDEYIYTLADLFNDW
What are the official names of this protein?
Uncharacterized protein R595.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS2_BURA4
Sequence: MAVTMRQMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMFTDAQKYVRQLAANRGTILFVGTKRQSRDTIAQEAQRAGMPFVNARWLGGMMTNFKTLKVSIKRLKDMEAAVEAGELEKMSKKEALLFEREIAKLQKSIGGVKDMGGIPDAIFVVDVGYHKIAVTEANKLGVPVIAVVDTNHSPEGVDYVIPGNDDSSKAVALYAEGVADAILEGRANAVNEVVQAARGDDEYVEENA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: DTD_CHLSY
Sequence: MRAVIQRVREASVTVAGEVVGAIGNGLLILLGVCHTDTAEDVELLAEKIAQLRIFSDHEGKFNLSLLDVGGAALVVSQFTLYADTRKGRRPSFTAAARPEIAAPLVDAFAAALRARNIPVATGVFGAMMQVALINDGPVTLVIDSAELRLPRRAGSRVDS
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_STAAE
Sequence: MTLYLDGETLTIEDIKSFLQQQSKIEIIDDALERVKKSRAVVERIIENEETVYGITTGFGLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELVRQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELNRQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHDVHAVRNFQEQINVAARMRDWLEGSTLTTRQSEIRVQDAYTLRCIPQIHGASFQVFNYVKQQLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERLVNPQLNGDLPAFLSPEPGLQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQEDHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGVEGLSPKTRRKYDEFRSIVPSITHDRQFHKDIEAVAQYLKQSIYQTTACH
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_DESVH
Sequence: MKTKFIFITGGVLSSLGKGLAAASVGALLKARGLKVTIQKLDPYINVDPGTMNPFQHGEVYVTDDGAETDLDLGHYERYLAEPMSQKNNYTSGSIYHRVITKERRGDYLGGTVQVIPHVTDEIKNAVLSLAEDDPDVALIEIGGTVGDIEGLPFLEAIRQLRGDLGKDRCLYIHLTLVPYLRAAGEHKTKPTQHSVKELRSIGIQPDIILCRCEEAITADLKRKIALFCNVDQDAVFSAVDVKNIYEVPLRFYEEGFDQKIAIMLRLPAKNPNLEPWETLVDTCAHPQGRVTIGIVGKYVDLKEAYKSLHEALVHGGVANKVAVDLKYVNSEEITEENVAEALKGLDGILVPGGFGYRGVEGKILTIRYARENRVPFFGICLGMQCAVIEFARNVMGLEDANSEEFNELSKNKVIYLMTEWFDHRRQAVERRDSSSDKGGTMRLGSYPCVVVPDTKAHDAYGVKHIDERHRHRFEFNKAYFDAMAQSGMVFSGLSPDGELVEIVELPDHPWFLGCQFHPEFKSNPMQPHPLFREFIRAAKTHPAGKR
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: CYB_DASGE
Sequence: MLNMRKTHPLLKIINHSFIDLPAPSNISAWWNFGSLLGVCLIIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNHGWLLRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMAMAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLAEWIWGGFAVDKATLTRFFAFHFILPFIITPLAIVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDALGFMLLLLILLLLALFSPDLLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIIPLLHTANQRSMMFRPVSQTLFWILTANLITLTWIGGQPVEQPFIIIGQLASMLYFTLILVLMPFAGLFENYMLKPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DAPA_DECAR
Sequence: MITGSIVAIVTPMHEDGSLDLNSFRNLLDFHVQEGTDAIVVVGTTGESPTVNVEEHCELIKIAVDHVAGRIPVIAGTGANSTAEAIELTEFAKKAGANMALSVVPYYNKPTQEGLYRHFKAIAEAVELPVILYNVPGRTVADMSNDTILRLAEVPGIVGVKDATGNIDRACDLIARAPKDFALYTGDDMTAVATISLGFHGDISVTANVAPRLMHEMCVAAASGDIAKAREIHFKVLALHRDLFCEANPIPVKWAVHKLGLMPNGIRLPLTTLSEANQPRVLAALRQAGLVA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_FERNB
Sequence: MGESYRIVLRTYAKLNLCLDVLGKRQDGYHEINSLFQNISLFDEMDITLSDGKGKLLINSNVNIGNNILNSVWELVNCDNKNVYVNLQKNIPMGGGLGGGSSNAAGFIIALEKVGIISKEQSLKIAQKVGSDVPFFLFGGTAIVKGRGEVILPVEPLTNFGKFKVDLHLPNFSISTKEAYSKLKAEWFGKAPITPEELYDFYKTRNFEMIKKGTYNIFERVIPMDLLEKIESLRRDFPAALTGSGSTYFALKEDGKYSFVPKGVEINAFEKS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: GPDA_LISIN
Sequence: MTQKKVAILGAGSWGTGLALVLADNNHKPVIWGNLDKIVNEINESHTNSHYLPDIILPTEVKATLSLDEAIDGAEIVVIAIPTNAMRVVCKQLNEALKEPTILVHVSKGIEPETNLRMSEVIEEEVDATKRKALVVLSGPSHAEEVALRHPTTLCASCKDLKAAEIVQDRFINNNLRIYTNDDVIGAEIGGALKNIIALGAGISDGLGYGDNAKAALMTRGMAEITRLGVAVGSNPQTFYGLTGIGDLIVTCTSVHSRNWRAGNMLGKGENLDEVLEKMGMVVEGVRTAKAVHGWAKKLDIDMPITESIYAILFENKDAREAVDLLMGRKKKIEKESF
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCYA_PROMS
Sequence: MLSESLTKSKLTDPLILDLLQNIREHRSMLEDLKSIKIDPKLTNIISKEIGRELYIENEFHKAKGFRKLHIEVAEFSKNLKILHCVFFPDPKFDIPIFGMDLVKINDIVSAAIVDLSPASQNQGLKYEKLLSEVDKSSFTSLREIPKWGGIFSNNVFFASLKRKSEKNDFCRVVDQYLTILIKLSKRAKPEVNEEIIQERIDFQKNYCVQQMKNEKTSMVLLKYFDEKWVNNYIKTVLFDF
What is the function of this protein?
Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
What are the official names of this protein?
Phycocyanobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: GATC_HALSA
Sequence: MTDAVDAEEIRHVADLARLRLDDEDVDTVVDHCGDILEHFERLEEVPEVDAEPELVNVMRADEIADSLDQDDALANAPETEDGRFKGPNVS
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: TSN2_MOUSE
Sequence: MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTMKDLSSEDKSPEYFYVGLYVLVGAGALMMTVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYSDYLKDRARGNGTLITFHSAFQCCGKESSEQVQPTCPKELPGHKNCIDKIETVISAKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI
What is the function of this protein?
May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath.
What are the official names of this protein?
Tetraspanin-2, Tspan-2.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SIRB1_ECOLI
Sequence: MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSLAKEEISQLLPLEEQLEKLIALFYGDWGFKASRGVYRLSDALWLDQVLKNRQGSAVSLGAVLLWVANRLDLPLLPVIFPTQLILRIECPDGEIWLINPFNGESLSEHMLDVWLKGNISPSAELFYEDLDEADNIEVIRKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEIRDRGLIYAQLDCEHVALNDLSYFVEQCPEDPISEMIRAQINNIAHKHIVLH
What are the official names of this protein?
UPF0162 protein YchA, Protein SirB1.
What is the protein family that this protein belongs to?
Belongs to the UPF0162 family.