PharMolix/UniProtQA huggingface dataset:
Protein: SAHH_METS4
Sequence: MPSNQDYIVRDIGLADFGRKEIAIAETEMPGLMAVRAEYAASQPLKGAKIAGSLHMTIQTAVLIETLKALGADIRWVSCNIYSTQDHAAAAIAAAGIPVFAVKGETLTEYWDYTARLFDWHDGGMPNMILDDGGDATMFVHAGLRAERGDTAFLDAPGSEEEEIFFALIKRMLKEKPKGWFAGLAESIKGVSEETTTGVHRLYILAKEGKLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMMAGKVAMVAGFGDVGKGSAASLRNAGCRVMVSEVDPICALQAAMEGYEVTTMEDAAPRADIFVTATGNKDVITIDHMRSMKDRAIVCNIGHFDNEIQVAGLKNLKWSNIKPQVDEIEFPDGHRIILLSEGRLVNLGNAMGHPSFVMSASFTNQTLAQIELWTNQGKYENQVYTLPKTLDEKVAALHLEKIGVKLTTLRPDQAAYIGVQASGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I329L_ASFPP
Sequence: MLRVFIFFVFLGSGLTGRIKPQVTCKYFISENNTWYKYNVTILNSSIILPAYNTIPSNAAGISCTCHDIDYLQKNNISIHYNTSILKTFQDIRIIRCGMKNISEIAGGFGKELKFLDLRYNDLQVIDYNILRKLIRSNTPTYLYYNNLMCGKRNCPLYYFLLKQEQTYLKRLPQFFLRRISFSNNNTYLYHFLSCGNKPGHEFLEYQTKYCRTKFPEINITVNQLIAKKNTERYKSCYPLVFISILCSCISFLFLFICLLRSICKKYSCTKQDKSSHNYIPLIPSYTFSLKKHRHPETAVVEDHTTSANSPIVYIPTTEEKKVSCSRRK
What is the function of this protein?
Viral TLR3 homolog that probably prevents TLR3 dimerization and subsequent induction of IFN.  Inhibits dsRNA-stimulated activation of NF-kB and IRF3.
What are the official names of this protein?
Transmembrane protein I329L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus I329L family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein.
Protein: RECR_BEII9
Sequence: MTAPIAGPEIERLIHLLARLPGLGPRSARRAALHLIRKRTELLGPLAEALQQAYNHLIPCQICGNIDTRDPCTICADAKRDPTLLVVVETVADLWALERAAALPARYHVLGGTLSPLDGVGPKDLNLQSLTERVAQGEIREVILAVNATVDGQTTAHYITDSLAAFPVKITRLAHGVPVGGELDYLDEGTLAAALRSRTNF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: HIS8_NEIMF
Sequence: MKSVRSFIRDDIQAMSAYQIADVPPGFAKLDSMESPVHPFAGHETLLQEWQARLAAAPIHLYPNPSGSGLQEALRSAFDIPDCADIALGNGSDELIQFITMLTAKPGAAMLAAEPSFVMYRHNAALYGMDYVGVPLNGDFTLNLPAVLEAVRKHRPALTFIAYPNNPTGVCFTRAEIEAVIEASDGIVVVDEAYGAFNGDSFLPQAGSIPNLIVMRTVSKIGFAGLRIGYAAGCPEVIGELQKILPPYNMNQLSLTTAKLALQHYGIISANIDSLKNERERMFAELGKICRLNTFPSQANFITIRVPDADLLFDTLKQNRILVKKLHGAHPLLEHCLRITVGSPAQNDAVLNIIRQLYCQPTDFL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ESF2_ASPFU
Sequence: MTTRKRNEFLDVVSDDDEGSDRAYDSEAAEESKGRLAKRRKTHTRADDLSDEESDIGRSESEDESKTRLKGKPKSKSQTTERSNDDDDEDEADDGEKMQVDQYLDATATLSPSQSRSQSPSTSSVTSKPTKLKKKPLDKVRPPKKNKTGVIYLSSLPPYLKPFALKSMLETRGFGPITKVFLTPEVPSNSAPRRRSNKRKSYADGWVEFASKKTAKICAETLNATIVGGKKGGWYHDDVWNMKYLKGFKWADLMEQVQRERSEREAKRRIEDTRARKEDKVFLQGVEQGKVLQGIQKKNEEKKKKKGETGTGEGSADAAANASELKVRRLFKQNEVKMGRDKVKDISALEDDAKRVLSKIF
What is the function of this protein?
Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis.  Required for the early cleavages at sites A0, A1 and A2 (By similarity).
What are the official names of this protein?
Pre-rRNA-processing protein esf2, 18S rRNA factor 2.
What is the protein family that this protein belongs to?
Belongs to the ESF2/ABP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HSLV_PELPB
Sequence: MKNNQRPVIRSTTVIGVIRDGKAALGSDGQMTLGNTVIKHSTRKIRRLYHGKLVAGFAGATADAVTLLDRFEEKLEAYNGKLDRAAVELARDWRTDKYLRRLEAMLAIVSHDKALIISGTGDVIEPEDGIVAIGSGSMYALAAARSLMKHSSLPAKEIVLESLKIAADICIYTNDHIIVEEV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF48_SYNP2
Sequence: MTSVLGLLKPLKKAIAAIAVLVLCIGCVQAPTISENPWQEIDLNTDSTFANIAFTDDLQHGWLVGTKETLFETTDGGKTWAERVIDLGDEKESFTGVSFSGQEGWITGRPSILLHTDDGGEHWSRIALSSQLPGAPYNITALGPNTAEMVTDLGAIYKTTDGGKNWKALVEGAVGVARTIERSADGKYVAVSARGNFYSTWSPGDTEWTPHNRNSSRRLQSMGFNGEDKLWLLARGGVVQFSDDTNPDNAEAWSEPVTPQYRNSVGLLHIGYRTPAELWAVGGSGSVVVSKDGGDTWFRDAALEEIPTNFYRVVFLNENKGFILGQQGVILRYDTSTEAA
What is the function of this protein?
A factor required for optimal assembly of photosystem II (PSII), acting in the early stages of PSII assembly.  Also plays a role in replacement of photodamaged D1 (psbA).  Assists YidC in synthesis of chlorophyll-binding proteins.
What are the official names of this protein?
Photosystem II assembly lipoprotein Ycf48.
What is the protein family that this protein belongs to?
Belongs to the Ycf48 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Lipid-anchor; Lumenal side. Note=Associated with a PSII precusor complex on the lumenal side of the thylakoid membrane.
Protein: RL20_VIBPA
Sequence: MPRVKRGVQARARHKKVLKQAKGYYGARSRVYRVAFQAVTKAGQYAYRDRRAKKRQFRQLWIARINAASRQNGLSYSRFINGLKKASIEIDRKILADIAVFDKAAFAVLVEKAKAAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PHS_BURCJ
Sequence: MIHKLTSEERKTRLEGLPHWTAVPGRDAIQRRLRFADFNEAFGFMTRVAIKAQEMNHHPEWFNVYNRVDVTLSTHDADGLTERDIELARFIDGAATHAQPGA
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: DGDG1_SOYBN
Sequence: MATHPQTPTSSNAFSFISKGWREVRDSADADLRLMRDRANSFKDLATSFDRELENFFNSATPPFSVPAMRSPPPKEIEFVKSLRPKLSEIRRAYSSPDFSKKVLEKWRPRTQIRINLSAIKNAIVSAEEEEEGIVDFEKRRRRRLSFWEEWKGEGEGESRDWEPIRVLKTRLKEFEKRGSSFDAFKNSEFVEKVKSSLKSMCKEPLESKEVPPLDVPELLAYIVKQSGPFLDHLGVKRDICDKIVESLYSKCKNHQLLHSLSGEESSVLGNGNINDELDLRIASVLQSTGHRYEGGFWTDHAKHDPLDNERHVAIVTTASLPWMTGTAVNPLFRAAYLSQSAKQKVTLLVPWLCKSDQELVYPSNLTFTSPEEQEAYIRSWLEERIGFKADFKISFYPGKFSEARRSIIPAGDTSQFIPSRDADIAILEEPEHLNWYHHGKRWTDKFNHVVGIVHTNYLEYIKREKNGALQAFLVKHINNWVTRAYCHKVLRLSAATQDLPKSVICNVHGVNPKFLKIGEKIAAERELGQKAFTKGAYFLGKMVWAKGYKELIDLLAKHKADLDGFKLDVFGNGEDANEVQSAARRLDLNLNFQKGRDHADDSLHRYKVFINPSISDVLCTATAEALAMGKFVVCADHPSNEFFRSFPNCLTYRTSEDFVTKVKEALENEPYPLTPEQRYQLSWEAATQRFMEYSELDGILNKENNGEKSRVDKGKLIAKSASMPNLTELVDGGLAFAHYCLTGNEFLRLCTGAIPGTRDYDKQHCKDLHLLPPQVENPIYGW
What is the function of this protein?
Involved in the synthesis of diacylglycerol galactolipids that are specifically found in thylakoid membranes.  Specific for alpha-glycosidic linkages.
What are the official names of this protein?
Digalactosyldiacylglycerol synthase 1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Symbiosome, peribacteroid membrane. Plastid, chloroplast outer membrane.
Protein: KBTB1_ECTVM
Sequence: MNNSSELIAAINGFRNSGRFCDINIVINDERINAHRLILSGASEYFSILFSSDFIDSNEYEVNLSHLDYQSVNDLIDYIYGIPLSLTNDSVKYILSTADFLQIGSAITECENYILKNLCSRNCIDFYIYADKYNNKKIETASFNTILRNILRLINDENFKYLTEESMIKILSDDMLNIKNEDFAPLILIKWLESTQQPCTVELLRCLRISLLSPQVIKSLYSHRLVSSIYECITFLNNIAFLDESFPRYNSIELISIGISNSRDKISINCYNRKKNTWEMISSRGYRCSFAVAVMDNIIYMMGGYDQSPYRSSKVIAYNTCTNSWIYDIPELKYPRSNCGGVVDDEYIYCIGGIRDQDSSLISDIDRWKPSKPYWQTYAKMREPKCDMGVAMLNGLIYVIGGVVKGGTCTDTLESLSEDGWMMHRRLPIKMSNMSTIVHAGKIYISGGYTNSSIVNEISNLVLSYNPIYDEWTKLSSLNIPRINPALWSVHNKLYVGGISDDVQTNTSETYDKEKDCWTLDNGHVLPYNYIMYKCEPIKHKYPLEKIQYTNDFLKCLESFIGS
What is the function of this protein?
Probable substrate-specific adapter of CUL3-containing E3 ubiquitin-protein ligases which mediate the ubiquitination and subsequent proteasomal degradation of host target proteins.
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein 1.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: SCRK_KLEPN
Sequence: MNGKIWVLGDAVVDLLPDGEGRLLQCPGGAPANVAVGVARLGGDSGFIGRVGDDPFGRFMRHTLAQEQVDVNYMRLDAAQRTSTVVVDLDSHGERTFTFMVRPSADLFLQPEDLPPFAAGQWLHVCSIALSAEPSRSTTFAALEAIKRAGGYVSFDPNIRSDLWQDPQDLRDCLDRALALADAIKLSEEELAFISGSDDIVSGIARLNARFQPTLLLVTQGKAGVQAALRGQVSHFPARPVVAVDTTGAGDAFVAGLLAGLAAHGIPDNLAALAPDLALAQTCGALATTAKGAMTALPYKDDLQRSL
What is the function of this protein?
Involved in sucrose metabolism.
What are the official names of this protein?
Fructokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: INSL5_HUMAN
Sequence: MKGSIFTLFLFSVLFAISEVRSKESVRLCGLEYIRTVIYICASSRWRRHQEGIPQAQQAETGNSFQLPHKREFSEENPAQNLPKVDASGEDRLWGGQMPTEELWKSKKHSVMSRQDLQTLCCTDGCSMTDLSALC
What is the function of this protein?
May have a role in gut contractility or in thymic development and regulation.  Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor.
What are the official names of this protein?
Insulin-like peptide INSL5, Insulin-like peptide 5.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SSI1_STRCI
Sequence: SLYAPSAVVISKTQGASADAPAQRAVTLRCLPVGGDHPAPEKACAALREAGGDPAALPRYVEDTGRVCTREYRPVTVSVQGVWDGRRIDHAQTFSNSCELEKQTASVYAF
What is the function of this protein?
Strong inhibitor of subtilisin BPN'.
What are the official names of this protein?
Subtilisin inhibitor-like protein 1, SIL-1, SIL1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I16 (SSI) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNTH_BACSU
Sequence: MMNKDITAQSPRSKAVQDALDGKIRGFRGLLPFLGPAFIAAIAYIDPGNFATNISAGSKYGYMLLWVILFSNIMALLIQSLSAKLGIATGKNLPEVAREEFPKPVSIGLWIQGELVIIATDLAEFIGAALGLYLLFGIPMLEASIIAAIGSFAILELQRRGYRSLEAGIAGMLFVVVIAFALQTFFAKPDAVSVMKGLFVPAFHGTDSVLLAAGILGATVMPHAIYLHSALTQRRVVGKTDAERKKIFRFEFIDILIAMLIAGAINASMLIVAAALFFKNGLFVEDLDVAFQQFGHLVSPMSAALFGIGLLVAGLSSSSVGTLSGDVIMQGFINYRIPLYVRRFITIIPPILIIASGVNPTTALVLSQVVLSFGIAFALIPLIMFTSNKRIMGSLINAKWITVVSWLIAVLIVALNVFLIVDTFR
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.  Involved in manganese uptake.  Can probably also transport cadmium, cobalt, copper and zinc, but not iron.  May be the predominant transporter of manganese during logarithmic phase growth.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENO_EXISA
Sequence: MSMITEIYAREILDSRGNPSVEVEVFTEDGGFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELIGYDVFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLPTPMMNIINGGSHADNNVDFQEFMIMPVGAPTFREALRMGAEVFHALKSVLSGMGLNTAVGDEGGFAPNLKSNEEAITVILEAIEKAGYKPGEDVYLAMDVASSEFYDKSTGKYELAGEGKSLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLLTDKIGHKVQLVGDDLFVTNTSKLAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDMLGDVAKYDGIKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: EFP_STRAW
Sequence: MASTNDLKNGLVLKLDGGQLWSVVEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTFNAGVKVETATIDKRDMQFSYMDGEYFVFMDMDTYDQLMVDRKSVGDAANFLIEGFTATVAQHEGEVLFVELPAAVELVIQETEPGVQGDRSTGGTKPATLETGHQIQVPLFITTGEKIKVDTRTSDYLGRVNS
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_RABIT
Sequence: MNENLFSSFATPTLMGLPIVALIIMFPTLLFPSPSRLINNRLVSTQQWLAQLILKQMMLMHSPKGRTWSLMLISLIMFIGSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGAVITGFRYKTKASLAHFLPQGTPIPLIPMLIVIETISLFIQPMALAVRLTANITAGHLLMHLIGGAALALVSISPTTALITFIILILLTILEFAVALIQAYVFTLLVSLYLHDNT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MRAY_SHEB8
Sequence: MLVYLAEYLTRFHTGFNVFSYVTFRAILGLLTALVFSLWFGPKLIERLQLLQIGQVVRNDGPESHFSKRGTPTMGGLLILAAIFISVLLWGDLGSRYVWVMLFVLGSFGLIGFIDDYRKVVRKDTKGLIARWKYILQSLAALLIAFFLYATAANPGETQLVVPFFKDVMPQLGAVFIVLAYFTIVGASNAVNLTDGLDGLAIMPTVMVAAAFALIAYLSGHAQFANYLHIPHLPGSGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLSLGAALGTIAVLVRQEILLVIMGGVFVMETLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISIFLVLLGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSB_THEAQ
Sequence: MARGLNQVFLIGTLTARPDMRYTPGGLAILDLNLAGQDAFTDESGQEREVPWYHRVRLLGRQAEMWGDLLEKGQLIFVEGRLEYRQWEKDGEKKSEVQVRAEFIDPLEGRGRETLEDARGQPRLRRALNQVILMGNLTRDPDLRYTPQGTAVVRLGLAVNERRRGQEEERTHFLEVQAWRELAEWASELRKGDGLLVIGRLVNDSWTSSSGERRFQTRVEALRLERPTRGPAQAGGSRPPTVQTGGVDIDEGLEDFPPEEDLPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: Y6521_BACAN
Sequence: MRVVTAKSIKKNRYNRMFAEEDLYSMLEEMGNTQQMINKFQKKRITQTILLSFFGLLLGLFFTSWCYLLALGLPFFFYRSKYTHVTKTYNAFKFERHLNFSKFTRLLIPYLKESGESTSLYQVFRKILNRMDNPVDKNSLAKLMSEMTDKPNDIQPFTDYAMRSSGSDMSINIMQTIYDFQQNSSDTNVINELGQMASAELQRAIDEIIAFKLRRFNFFPTKIVMSSFILVVGFAAAVLVHHLSSINLS
What are the official names of this protein?
Uncharacterized protein pXO2-22/BXB0021/GBAA_pXO2_0021.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SIVA_RAT
Sequence: MPKRSCPFTDAAPLQLKVHVSPRELSHGVFAERYSREVFERTKQLLFQGAQAYRDHIWGEGCSINHLPEPLKPGLVGAPQAARGQMLIGPDGRLTRCQAQASEAGLPGAAPIACSSCVRSVDGKAVCSQCERALCGQCVYTCWGCGALACVLCGLADYADDDDGEKTLCTSCAMFEA
What is the function of this protein?
Induces CD27-mediated apoptosis.  Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity.  Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis (By similarity).
What are the official names of this protein?
Apoptosis regulatory protein Siva, CD27-binding protein, CD27BP.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In the nucleus, accumulates in dot-like structures.
Protein: MIAB_SALTO
Sequence: MTTAAASSPRTYQVRTYGCQMNVHDSERIAGLLEQAGYLRAGAADDTPDVVVFNTCAVRENADNRLYGNLGQLRPRKDQHPEMQIAVGGCLAQKDRSEIVRRAPWVDVVFGTHNIGSLPVLLERARHNAAAEVEILESLEVFPSTLPTRRESTYAGWVSISVGCNNTCTFCIVPALRGKEKDRRPGEILSEVRSLVDEGVLEVTLLGQNVNSYGIEFGDRYAFGKLLRACGDIDGLERVRFTSPHPKDFTDDVIAAMAETPNVCPSLHMPLQSGSDDMLRAMRRSYRSERYLGIIEKVRAAMPDAAITTDIIVGFPGETEADFERTLDVVRAARFSSAFTFQYSKRPGTPAATMADQLPKAVVQERYERLIDCVEEITWAENRRLLGKTVEVLVAVGEGRKDERTGRLSGRARDGRLVHFDAGSLAGQVRPGDIVQTVVTYAAPHHLNADGEPLAHRRTRAGDAAEAGQRPRTAGVSLGLPTVGAPPPMPPAASSACSC
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MX1_MACMU
Sequence: MVLSEVDIVKADPAAASQPLLLNGDADVAQKSPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDEWRGKVSYQDYEIEILDASEVEKEINKAQNTIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPPDIGYKIKTLIRKYIQRQETINLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREKIFFEDHPHFRDLLEEGKATIPCLAEKLTSELIAHICKSLPLLENQIKESHQGITEELQKYGVDIPEDENEKMFFLIDKINAFNQDITALIQGEETVGEDDSRLFTRLRREFHKWGIIIENNLQEGHKITSRKMQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVNMLHTVTDMVRLAFTDVSMKNFEELFNLHRTAKSKIEDIRTEQEREGEKLIRLHFQMEQIVYCQDQVYRGALQKVREKELEEEKKKKSWDIGTFQPSSTESSMEEIFQHLMAYHQEASKRISSHIPLVIQFFMLQMYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQFPG
What is the function of this protein?
Interferon-induced dynamin-like GTPase with antiviral activity.
What are the official names of this protein?
Interferon-induced GTP-binding protein Mx1, Myxoma resistance protein 1, Myxovirus resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Note=Binds preferentially to negatively charged phospholipids.
Protein: NRDR_SHEB9
Sequence: MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGSRQPFDEEKLQGGMLRAVEKRPVSMDEIEQALSKIKSTLRATGEREVPSEMVGNLMMEQLMSLDKVAYIRFASVYRAFEDVSEFGEAIAKLQK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ISPE_CLOB6
Sequence: MLSKAHAKVNLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKGIIIDCDREYIPKDRRNLAYKAAELFLDRYNIDSGVRIDITKNIPVAAGLAGGSTDAATVLKIMRDIFRPDISNEELKEIALDIGADVPFCIEGGTALCEGIGEKITPIKNFKNQILVLVKPNFGLSTKDVYNNLKVEKIYIHPNTTKLIQSIEEDNLKSVARNMRNVLENVTLRKYKALNSIKSNFIELGALGSMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: UBIA_SHESA
Sequence: MNLKQKWDVYSRLTRLDRPIGTLLLLWPCLMALVLAAGGMPDIKVLIIFIIGVVIMRACGCIINDYADRDLDSHVERTKSRPLASGEISTKEALLLFVILGLAAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRVTNMPQMFLGVVWSWSIPMAYAAQTGEVPIEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQLAALLCFIAAGWSADRGLLYGLGLLTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CF163_MOUSE
Sequence: MIRNPNYTDFVCCAVCNKIIPPAPFGETFKRIYDYKPFKTRFYTHKDILDIGASILNKEEEFRETVFKEQIKKAEAKVWEKAELLQKQAVDQAVEDAEARHKFEIRVLEEQHQKDLKALEDKTKVNMIQQMKEELNREHTAAEQRMVHRIQRIMMECHQEKMEAVKKAREEERRIAQKAIEEEKSKVLEEFVTTGVTVIKDKKTSLGQLIKAKEHEMTIYYGMAQRQKQEEVQEVLQEAEKTHQATLDNMMGKLVNTQGELLSVAKQLGIMTNWKDFLEEELQETRAAFQKYINYTFPRLSPGHADFILPERKKTPSILAKENEPRTD
What are the official names of this protein?
Uncharacterized protein C6orf163 homolog.
Protein: SYR_STRPC
Sequence: MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFSLAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSDYAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGDWGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLEDGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLDLLEAKNLLVESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNEQAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINRAASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYVQYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMAKFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.