PharMolix/UniProtQA huggingface dataset:
Protein: CCMA_PSEAI
Sequence: MLEALDLAGVRGERRLFDHLTFRIVPGECLSVHGENGSGKTTLLRTLAGFATPAAGRVLWKGKPLRNQWSEYQRELVYNGHGIGLKEDLNALDNLLAAAAIAGEPVTTECVESALDEVGLAEHRHLPFRMLSQGQKRRASLARLLLYRRKLWILDEPSTALDQFGARWLGELIHRHQSRGGMVVLTSHQELALKTSQTVRMGA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HMMR_RHILV
Sequence: MNIGEASERSGLPSKTIRYYEDIGLIRPERGGNGYRDYAATDVHKLRFLQRSRGLGFSVEECRQLLALYEDKDRASADVRDIAQTKLTEIDRKIRELTELRRTLEHLVHACHGNDRPDCPILEELSDGA
What is the function of this protein?
Regulates the transcription of actP.  It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations.  In the absence of copper, it negatively regulates the transcription of actP.
What are the official names of this protein?
HTH-type transcriptional regulator HmrR, Copper efflux regulator, Copper export regulator.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_VIBC1
Sequence: MSDNNQCVIVGIAGASASGKSLIASTIYNELREKVGDHQIGVITEDCYYNDQSQLSMEERVKTNYDHPSALDHDLLCEHLEKLVRGEAVEVPEYSYTEHTRTSNTTPMTPKKVIILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVEERGRTMESVLKQYQQTVRPMFMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKA
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_LEPBJ
Sequence: MPKHSALERAWPAKEIVEDLLELRKRSPLTHIMTNIVVTNWTANVLLAVGASPAMVIAEEEAGEFVKIANGLLINVGTITSNDAKAMKIAATVAHQTNTPWVLDPVAVGALGFRTETTKKLLDLKPTVIRGNASEILTLAGIAGKGKGVDSTVNSKDALPYAQELSGKTGAVVAVSGEVDYVTNGKETIEIYGGDPIMTKVTGVGCSLGALIASFLGIQKDPLRASASASAVFAIAGSRSAKKSNGPGSFAINFIDQLSQLSIE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: LAP5_TRIVH
Sequence: MKVLAALALSALAMAKPTPPMPGMSLVQTGPQETRWVTAKEKHDMVMNHIGFFDITNRPESASIASKPKSYAFPGNVSHQAEVKPLLEKISADHIKSNLEMFSSYPNRYYDAQSGVESAQWVMEQAQAVVGNIQGAKVEMVKHDWMQPSIRAIIPGKSEKIVAVGAHQDSINGKNPQGEAPGADDNGSGSMTILEALTALVSDQKIAGGEAANTLEFHWYAGEEEGLLGSQDIFQQYSQEGKEVVAMLNQDMTGYGETMGVITDNSDPNLTKFTKMILDTYTSAKYSDSECGYACSDHASANKAGFPSAFVYEAVVGQDNPAIHSPDDTIEKLDPAKMAEHAKLVVGFAYELAFATL
What is the function of this protein?
Probable extracellular aminopeptidase which contributes to pathogenicity.
What are the official names of this protein?
Probable leucine aminopeptidase TRV_02148.1, Leucyl aminopeptidase TRV_02148.1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH601_SALAI
Sequence: MAKMIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQAMVREGLRNVAAGANPMALKRGIETAVASVSEELLKLAKDVETKEQIASTASISAGDPSVGEIIAEAMDKVGKEGVITVEESNTFGLELELTEGMRFDKGYISAYFMTDPERMEAVFDDPYILIVNSKISSVKDLLPILEKVMQSGKPLLIIAEDIEGEALATLVVNKVRGTFKSVAVKAPGFGDRRKAMLGDIAILTGGQVISEEVGLKLDAVNLDMVGRARKVVVTKDETTIVDGAGDAEQIQGRVNQIRAEIDKSDSDYDREKLQERLAKLAGGVAVIKVGAATEVELKERKHRIEDAVRNAKAAVEEGIVPGGGVALVQAGKTAFDKLDLTGDEATGAQIVKIALDGPLRQIAVNAGLEGGVVVEHVRGIEAGHGLNAATGGYVDLMAAGIIDPAKVTRSALQNASSIAALFLTTEAVVADKPEKTPAAPAAPGGGEMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOT1_SCHPO
Sequence: MKSQEQQTPETREKSSSTSESGHPISLDSKTPPPNDSKIESIVKAQILFLLSTLREDQYDTKLEQIRQLINKNAPRVYHHFLRRLIQGNSYRIFGTGKSSDGLATYKLLLDELKSLTKSWVMAKRFSDAISGSDSEVFEDFDIEAFLDHFQFSPLERTNLLIGLTTSVKPTLAKKASALLKNTFQSLLNQLSDPTQQQSIDKNDLDLLREGLFTTDYDRIPLIKVPKFDAIIEKKLANSRPLTALFGPMKASKATLKSMKEAILKKYPPGTATETDVAYLINSLVAIHDYGAWDTVLMGKAIVSSFENLNWEAMLSMFDNPKFMITGTPSLVLFFTIFTNAYKLRQTNFTLDFLWVLWRNPLPQLSIISHIILSPTSMFDIREFNVNPVVSVDSLKDYSEELVNYAKIYEKSNLNCIELVQILLRLLSEVVTYETSLFLNFLDEKVSAELLLLGTLQLPLAWNPVQESLAFQWCSDFFSNFKEHKFVFVRIERTNPQFLFAFLRSLWLKDSSSVNQVVEFIIENDFTSHIGNIQPNRFALEIAALAAARKALSFQDWLDKKMLEFEDADGLNVFLVEVLDFLMSRAALQKNESEQKEESVVLSIDTVNVLLTTLMDNVSISEEVSEHIKDVQILCLQVYPRLFSLGHDRDSIVIATNTTNSFSPDVESEVESYFQALYERRISIGKIVLTLQNFKKSENPRDLDLFACLQHSLFDEYRFFPDYPLEALALTAVLFGSLIQFELLSFVPLGVALRYVYQALLMPTDSKMFRFGMQALVQFQEKLPKYINYCNLILGIPSLQLVRPDIYDSIREMIASNENTEVEKDKLDSFSALANPASPKAPEYTFVSIHVPPLNVPNAEGEIEESVCDNILFAINNLSQLNFNEKLKDVKDNLTPAYLPWFSHYIVTQRVSREANFLSLYGKFLEELKSSDLYKIVFRDTLQAILDIMNNNAETLSPSEKTNLKNLGSWLGSITLLRNKPITTLQVSFKDLLLEGIDSGRIDRVLPFVCKVLEKASSSVIFKPPNPWLMGILKLLVELYQFADFRLNLKFEIELLLNNLNVKMDNIEPSEMYRNHLVQKADLEKELPEDVLNAEFPDGTDVITQYIVAASSQITVTDAVAQVFGKPKPAIKNITQLIIQQSVLEIISAVVRRSVGIAAITTKSLLQKDFAAESNPSRLLLAARQMAKTLAGNLAMVTCREPLQMLMINNFRTIALQDVENVHAAVAQAIDELVSQNLFVASSVIESVASETAIAEIDAEIEHMIVERVRHRKTTPNLPFVDPAGAANLHLNLPSVLKLSSELTPQQFQLYENFDRLSLSTIMSNNSFTSLNGLRTDSADSTDALNSNLNNTVENEANQTALNYARNLLIIIGQLFQLAAQMPYTSMQEVPADHELHELVNQFLTGVASINHPIADHVFLLCAQECCRILLTDSKSPFILEVFSAILEYICQASTKTAINVSLYWNFSNDLEKLNLPIILSLIRFGILTSGEVDYHVARGVRSEQGSGPVTDFAIELLRTAVGGENPMALPGNFVNSITSLYEISESFSGETKQAYEQLVETMNKSVSPASEILSDLDNKQQLNDQIIIVFVSWVHLLRNSATNDETKAAFVYQLHKQGILSEPELCIQFFRCNLEAVLVAFLEAASVNAPDYFNVDAYASLLVNVVKYTEGSTEGTVSSKSVLFRKIIALIIGVFAELHNSMAEFVHQKTFFRLFSSILSELDDAKDVLESCFVDIYSVILECFLAIQPRSFPAFTFAWLSLISHSYLLPKVLLVNNDKINDLFSEILMSFLKFLDLKDDIDKAQFKLLYNGFLRIILVLLHDFPGFLATHCYQLIPYIPLECVQLRNMVLSAFPSDLHLPDPFAQGLKVGRLPEVTRAPLISNSVSASLEKFASALDLEACFSSSKPAEVAKLLLEVYSSQDTPTKLNEWANYFMLCLIRHATRDSPAKQAPQFQSKSPECVIISTMNRSCDSKCRYFLLTAIANQLRYPSSHTYYASCCFLYLFKSSSNNPQELLIKEQMTTVLLERIICNRPHPWGLLITFTELLKNEDYNFWKHPYIKRNDEICRLFDSLHEHVMAPSSANNVSTEEATELMGQV
What is the function of this protein?
Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.  The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes.  Preferentially affects TC-type TATA element-dependent transcription.  Could directly or indirectly inhibit component(s) of the general transcription machinery (By similarity).
What are the official names of this protein?
General negative regulator of transcription subunit 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PNP_MYCUA
Sequence: MSVAETEEGVFEATATIDNGSFGTRTIRFETGRLAQQAAGSVVGYLDDENMLLSATTASKNPKEHFNFFPLTVDVEERMYAAGRIPGSFFRREGRPSTDAILTCRLIDRPLRPSFVNGLRNEIQVVVTILSLDPNDLYDVVAINAASASTQLAGLPFSGPVGGVRVALIDGQWVAFPNVEQLERAVFDMVVAGRIVGTEEDGTPDVAIMMVEAEATDKVIELVEGGAPAPTESVVAQGLEAAKPFIAALCTAQQELADASGATVKTGAEYPVFPEYGDDVYYAVSSVATDGLAAALTIGGKAERNQRTEEIKAEVLERLADTYEGREKEIGAAFRSLTKKLVRQRIVTDHFRIDGRGVTDIRALSAEVALVPRAHGSALFERGETQILGVTTLDMVKMAQQIDSLGPETTKRYMHHYNFPPFSTGETGRVGSPKRREIGHGALAERALMPVLPSVEEFPYAIRQVSEALGSNGSTSMGSVCASTLALLNAGVPLKAPVAGIAMGLVSDDVEVDGKTERRFVTLTDILGAEDAFGDMDFKVAGTKDFVTALQLDTKLDGIPSQVLAGALAQAKDARLTILEVMAEAIDTPDEMSPYAPRVTTIKVPVDKIGEVIGPKGKVINSITEETRAQISIEDDGTVFVGATDGPSAQAAIDKINAIANPQLPTVGERFLGTVVKTTDFGAFVALLPGRDGLVHISKLGKGKRIAKVEDVVNVGDKLRVEIADIDKRGKISLVLVAEDDDSAAAAAADSPAPADAATASS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPA_STAS1
Sequence: MKQGTVKWFNAEKGFGFIEVEGENDVFVHFSAINQEGYKSLEEGQSVEFEVVEGDRGPQAANVVKL
What is the function of this protein?
Involved in cold stress response.
What are the official names of this protein?
Cold shock protein CspA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOTI_DROVI
Sequence: MEQGVVEELIHLQLPEVEAVDVVNVPDGNGDGDGDGDGDGNDAWERQLDEVQMQAMRLENPQVAMLLDAPHEPPIELHHMLEPVNVPQRPRKKRSFLTISKPFHVQPERCALISNGWRAVQCVQPEKRGEYFANYLIKHMNSRNYPNGEGLPNRWGQF
What is the function of this protein?
Post-meiotically transcribed gene that has a role in late spermiogenesis; required for actin cone progression during spermatid individualization.
What are the official names of this protein?
Male-specific protein scotti.
What is the protein family that this protein belongs to?
Belongs to the male-specific scotti family.
Protein: RL15_NEIMB
Sequence: MFLNTIQPAVGATHAGRRVGRGIGSGLGKTGGRGHKGQKSRSGGFHKVGFEGGQMPLQRRLPKRGFKSLTASANAQLRLSELESIAVNEIDILVLKQAGLIASTVSNVKVIASGEISKAVALKGIKVTKGARAAIEAVGGKIEM
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: GLMU_SYMTH
Sequence: MSDITAVLLAAGHGTRMKSDLIKVMHPLAGKPMIGHIVDNVRRAGLEDIVVVVGYQQERIREYLGDRVRYAVQSEQLGTGHAVLQAAGLIDETEGGHVLVMYGDNPFIGPELIERLIRAHVEADAAASLLTAELADPGALGRILRDPATGAFLGSVEYKDATPEQRRIREIWTGVAVFRRAGFTALLNRLDRNNAQGEYYLPQVWEILLQRGEKVQALLLASEEDALAPNDRVELARAEARLRRQINERHMRNGVTIINPDATYIDEDVEIGRDTVIWPFTFIHGKTVIGPHCKIGPMTTIVSSTVAEGCVVEQSVVEESYVGPGCRIGPMAHLRPGCELEGAAEIGNYAELKKAKVGRGVKCHHHSYLGDATIGAGANIGAGTITANYNGVEKFRTEIGSGAFIGTNVNLIAPITVGDGALIAAGSTVGPRLEIPADALVVERAQAVIKEGRAASLKEAWRQRKMNREGT
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_RICRS
Sequence: MSEIWEDAIKSNAWPFVEAKKILDSLNGQIPEKGYVLFETGYGPSGLPHIGTFGENARMVMVQKAFEQLSDIPTKLICFSDDMDGLRKVPSNIPNPEMVAQYMDMPLTSIPDTFGECESYGHYMNAKLRSFLDKFGFEYEFYSSTNCYKAGMFDEMLIMVLEKYDEIMELMLPTFREERKATYSPFMPICPKTGKVLQVPIEKWDAKAGTVTYKDKAGNYIEVPVTGGHCKLQWKPDFGMRWAALKVDYEMYGKDHLANARLYSEICRILGGKPPVQLCYELFLDENGEKISKSKGNSISIDDWLKYAPVESMALFMYQNPTRAKRLFFDVIPKNVDEYITFNQKYHLEEDRAKRVANPVYHIHHGNVPKIETFGITYSLLLNLTSVCNPSDKSVLWGFISKYEPQATPNTNPYLDHLAEFAIRYYNDFIKAHKSYLSPSEKHKVILQDILDMLSDIADQTEAEAIQKAIYDIGMKAGYANLRDYFKDLYQILLGQNEGPRLGTFIKLYGVQEMKKLVEGQL
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNA6_MOUSE
Sequence: MRSEKSLTLAAPGEVRGPEGEQQDAGEFQEAEGGGGCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFMEEIRFYQLGEEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNEGSGTRLSPASRSHEEEDEDEDSYAFPGSIPSGGLGTGGTSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKAAFFRNIMNIIDLVAIFPYFITLGTELVQRHEQQSVSGGSGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDVDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPTPDLKATDNGLGKPDFAEASRERRPSYLPTPHRAYAEKRMLTEV
What is the function of this protein?
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes.  Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient (By similarity).  The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (By similarity).  Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel (By similarity).  Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation (By similarity).  Homotetrameric channels display rapid activation and slow inactivation (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily A member 6, MK1.6, Voltage-gated potassium channel subunit Kv1.6.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.6/KCNA6 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UVRB_DEHM1
Sequence: MPDFKIVSDFALTGDQPQAVEKLSEGLAHGLTDQTLLGVTGSGKTFTMANVIARVNRPTLIISHNKTLAAQLYSEMKEFLPENSVEYFVSYYDYYQPEAYVPQKDMYIEKDADINEEIDKLRHAATRALFERRDVVIVASVSCIYGLGEPEEYRSFVLPLKKGQSLRRDLILRRLVDMQYERNDIDFSRGKFRLRGDTLEIQPAYEELALRVEFFGDEIERIVSLDPVSGELLADIDEINIYPAKHFVTSAEKMAEAIKGIQAELEDRLKELEAEGKMLEAARLKQRTNYDLEMMQQAGYCSGVENYSRHLAGRKAGSAPWTLLDYFPEDFLLIVDESHMSLPQIRGMYAGDAARKKTLVDYGFRLPSAMDNRPLSFDEFKARVKQAIYVSATPGPYEKEHSQQVVEQLVRPTGLLEPVITVKPTGGQIDDLLEEVKKRVDKKERVLITTLTKKMSEKLADYLVEMGIKTHYLHSEVDTLERVEILRDLRLGVYDVIVGINLLREGLDLPEVSLVAILDADKEGYLRSEQALIQTMGRAARHVDGQVIMYADKITGSMQRAMDEISRRRKIQEDYNRLHNITPQGIRKAIKDINERIRSVTAEVSGPEFRPAPTLREDIVRLIKELESQMKKAAKNLEFERAALIRDRVVELRAALETDPVNKNERTK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_STAAS
Sequence: MTNKDESVEKNTESTVEETNVKQNIDDSVEQAEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO07_BPHC1
Sequence: MATKNRTIIKKYADRWHKEACHLYAKWLNAKRQGDEEAANYYFSKYITAGDNWINYTKFAH
What are the official names of this protein?
Uncharacterized 7.3 kDa protein in cox-rep intergenic region, ORF23, ORF7.
Protein: MDTC_ECO7I
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPSASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRARLPELQSTIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRVLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQANASYQYTLLSDDLPALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQAVTE
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WCAM_SALTY
Sequence: MPATKFSRRTLLTAGSALAVLPFLRALPVQAREPRETVDIKDYPADDGIASFKQAFADGQTVVVPPGWVCENINAAITIPAGKTLRVQGAVRGNGRGRFILQDGCQVVGEQGGSLHNVTLDVRGSDCVIKGVAMSGFGPVAQIFIGGKEPQVMRNLIIDDITVTHANYAILRQGFHNQMDGARITHSRFSDLQGDAIEWNVAIHDRDILISDHVIERINCTNGKINWGIGIGLAGSTYDNSYPEDQAVKNFVVANITGSDCRQLVHVENGKHFVIRNVKAKNITPGFSKNAGIDNATIAIYGCDNFVIDNIDMTNSAGMLIGYGVVKGKYLSIPQNFKLNAIRLDNRQVAYKLRGIQISSGNTPSFVAITNVRMTRATLELHNQPQHLFLRNINVMQTSAIGPALKMHFDLRKDVRGQFMARQDTLLSLANVHAINENGQSSVDIDRINHQTVNVEAVNFSLPKRGG
What are the official names of this protein?
Colanic acid biosynthesis protein WcaM.
Protein: PNCB_RHILW
Sequence: MARTDIARRVYNHAWKLDPIIRSLIDTDFYKLLMLQMIWKLYPDVNASFTLINRTKRVRLADEIDEGELREQLDHARTLKLSKKEMIWLAGNSFYGRAQIFEPEFLAWLSNFQLPEYELSKKDGQYVLDFHGSWKETTMWEIPALAIVNELRSRSAMRALGPFTLDVLYARAKAKMWSKVERLKELPGLRISDFGTRRRHSFLWQRWCVEALKEGIGPAFTGTSNVLLAMDSDLEAVGTNAHELPMVAAALAQTDEQLRNAPYKILRDWNKLYGGNLLIVLPDAFGTAAFLRDAPEWVADWTGFRPDSAPPIEGGEKIIDWWKKMGRDPRQKLLIFSDGLDVDAIIDTYRHFEGRVRMSFGWGTNLTNDFSGCAPTEISGLNPISVVCKVSDADGRPAVKLSDNPQKATGDPAEVERYLKFFGAEDRIDQTVLV
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: SYY_METST
Sequence: MDIDASVENISKDTAEIIEVEELKELLKKDEKRAYVGFEPSGKVHLGHALTIKKMKTLQDAGFKITIFIANLHAYLNNKGTLDELNEVAKYNIKCFKALGLSEDTNFILGSDRMTPEYITEVFKAAKLTTIQRAQRSMALVSRNETHDVAQTLYPIMQALDIHDLDADIAVGGMEQRKIHMLAREILPRLGYRPPVCIHIPLIHGTDGSDKMSSSKGNFIAIDDTPKEIKNKINKSFCPIGVSEDNPVMEIAHYYIFDTHEKILIERPEKFGGNLELTEEELIQTYENEDLHPMDLKNTVSKYLIERLAPAREYMENN
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK32_DAUCA
Sequence: MAVPKKRTSISKKRIRKNIWKGKGSWAALKALSLGKSLSTGNSKSFFVRQKKNKS
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: INT14_MOUSE
Sequence: MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESNRFPLPFPFPSKLYVMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPEPFVIDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGAGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVALVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTEYAIYDHNITPLHTDFSGSSTERM
What is the function of this protein?
Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 14, von Willebrand factor A domain-containing protein 9.
What is the protein family that this protein belongs to?
Belongs to the INTS14 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBIL_NPVOP
Sequence: MQIFVKTLTGKTITVETEPGDTVGQVKQKIADKEGVPVDQQRLIYAGKQLEDAQTLADYNIQKESTLHMVLRLRGGNGLRKGKRRCLSLLQFI
What is the function of this protein?
Ubiquitin may play a role in viral life cycles, or in virus-host interactions.  It is covalently linked to coat protein subunits of several different plant and animal viruses.
What are the official names of this protein?
Ubiquitin-like protein.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
Protein: ACYP_LISW6
Sequence: MARDTAILRVTGFVQGVGFRYTTKHVAYKYDVSGTVKNLDDGSVEIHAIAEEENLNKFIDAIKKGPSPGCRIEHVYIYKGAPVEDRKTFDIVY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: AROE_NEIM0
Sequence: MTALPRYSVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFGTGGCGANVTVPFKQEAFHLADEHSDRALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADVNGGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADGLGMLVGQAAASYALWRGFTPDIRPVIEYMKAM
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.