PharMolix/UniProtQA huggingface dataset:
Protein: BUK_BACCN
Sequence: MSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDTGEIKKYKRIIDQYEFRKETILEILHSHGINISKLSAVCGRGGLLRPIEGGTYTVNEAMLEDLKNGYSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQKAVARKVAAEIGHKYEDLNLIIAHMGGGITVGAHKNGKVIDVNNGLNGEGPFSPERAGTVPVGQLIEMCFSGNYYRDEMMKKIVGQGGLVSLIGTNDAIKVENMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSKILINEIKERVNWIADVIVHPGEDELQALAEGALRVLREEEAPKEYVVREKETVARG
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO4A1_BOVIN
Sequence: MGPRLGVWLLLLLAALLLHEESSRAAAKGGCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPSGVPGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPVGPPGLPGFAGNPGPPGLPGMKGDPGEILGHIPGTLLKGERGYPGQPGAPGSPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGEKGDQGVSGPPGLPGQAQVITKGDTAMRGEKGQKGEPGFPGLPGFGEKGEPGKPGPRGKPGKDGEKGEKGSPGFPGDSGYPGQPGQDGLKGEKGEAGPPGLPGTVIGTGPLGEKGEPGYPGGPGAKGETGPKGFPGIPGQPGPPGFPTPGLIGAPGFPGDRGEKGEPGLPGVSLPGPSGRDGLPGPPGPPGPPGQPGHTNGIVECQPGPPGDQGPPGIPGQPGLTGEVGEKGQKGDSCLVCDTAELRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGLEGLPGPQGAPGLMGQPGAKGEPGEIYFDIRLKGDKGDPGFPGQPGMPGRAGSPGRDGQPGLPGPRGSPGSVGLKGERGPPGGVGFPGSRGDIGPPGPPGFGPIGPIGDKGQIGFPGTPGAPGQPGPKGEAGKVVPLPGPPGAEGLPGSPGFQGPQGDRGFPGSPGRPGLPGEKGAIGQPGIGFPGPPGPKGVDGLPGDAGPPGNPGRQGFNGLPGNPGPPGQKGEPGVGLPGLKGLPGIPGIPGTPGEKGNVGGPGIPGEHGAIGPPGLQGLRGDPGPPGFQGPKGAPGVPGIGPPGAMGPPGGQGPPGSSGPPGVKGEKGFPGFPGLDMPGPKGDKGSQGLPGLTGQSGLPGLPGQQGTPGQPGIPGPKGEMGVMGTPGQPGSPGPAGVPGLPGAKGDHGFPGSSGPRGDPGFKGDKGDVGLPGKPGSMDKVDMGSMKGEKGDQGEKGQTGPTGDKGSRGDPGTPGVPGKDGQAGHPGQPGPKGDPGVSGIPGAPGLPGPKGSAGGMGLPGMPGPKGVAGIPGPQGIPGLPGDKGAKGEKGQAGLPGIGIPGRPGDKGDQGLAGFPGSPGEKGEKGSTGIPGMPGSPGPKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGIKGEAGLPGKPGPTGPAGQKGEPGSDGIPGSVGEKGESGLPGRGFPGFPGSKGDKGSKGDVGFPGLSGSPGIPGSKGEQGFMGPPGPQGQPGLPGTPGHAVEGPKGDRGPQGQPGLPGRPGPMGPPGLPGLEGLKGERGNPGWPGTPGAPGPKGDPGFQGMPGIGGSPGITGAKGDVGPPGVPGFHGQKGAPGLQGVKGDQGDQGFPGTKGLPGPPGPPGPFSIIKGEPGLPGPEGPAGLKGLQGPPGPKGQQGVTGSVGLPGPPGEPGFDGAPGQKGETGPFGPPGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTTDDPQCPPGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPQCPTGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT
What is the function of this protein?
Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation.  The C-terminal half is found to possess the anti-angiogenic activity.  Specifically inhibits endothelial cell proliferation, migration and tube formation.
What are the official names of this protein?
Collagen alpha-1(IV) chain.
What is the protein family that this protein belongs to?
Belongs to the type IV collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: MURI_STRE4
Sequence: MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGPRPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASAAIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSVAKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLLNYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: MFS1_ARTBC
Sequence: MTEKDTDGADGLTKAKSNAVSEDYETVNHVTGLKLAVIVTGLCLSVLLVALDNTIIATAIPKITDQFHALEDIGWYGSSYLLTICAFQLIFGKIYTFFPVKWVFLIAITIFEIGSAICGAAPNSTALIIGRAVAGIGSAGIFSGALIIIAYSIPLEKRPAYTGAIGGMYGIASVAGPLMGGAFTDHISWRWCFYINLPIGAVTILSILIFLKHPKQKLDNNQTWKARLLKLDPIGTAFFMPSIICLLLALQWGGTKYPWNNGRIIALFVVFAVLISGFIYFQIRGGDSATVPPRILKKRSIASGAFFLFTIGSAFFIMVYYLPIWFQAIKGASATSSGIMNIPMVLSLVVLSIASGITVTAIGYYAPLYYVSTVLTSIGAGLLTTFTTETSKGKWIGYQIIFGAGVGTGLQLSIIAAQAVLPLEDVAVGTVIMMFCQTLGGALFVSVGQNVFTNLLVKGVVNAAPGLDPQVVLRVGATQLKNMIPPQFLDGVQVAYNDALTKTWYVATALAALSVIGSVGMEWKSVKGKKIEPAAA
What is the function of this protein?
MFS-type efflux pump involved in the modulation susceptibility to azoles, including fluconazole, itraconazole, miconazole and voriconazole (Ref. 2).  Confers also increased resistance chloramphenicol and thiamphenicol, suggesting that it acts as a pleiotropic drug transporter with a broad substrate spectrum (Ref. 2).  Finally, increases the tolerance to cycloheximide when expressed in S. cerevisiae, but not in dermatophyte species (Ref. 2).
What are the official names of this protein?
MFS-type efflux pump MFS1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDHR_ECO57
Sequence: MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQFDVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLETRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEAAHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAREASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN
What is the function of this protein?
Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd.
What are the official names of this protein?
Pyruvate dehydrogenase complex repressor.
Protein: SOSSC_CHICK
Sequence: MAANPSGQGFQNKNRVAILAELQEKRKLLMQNQSSTNHPGASIALARSPLNKDFRDHAEQQHIAAQQKAALQHAHAHSSGYFITQDSAFGNLILPVLPRLEAE
What is the function of this protein?
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint.  The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability.  Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) (By similarity).
What are the official names of this protein?
SOSS complex subunit C, INTS3- and NABP-interacting protein, Sensor of single-strand DNA complex subunit C, Sensor of ssDNA subunit C, SOSS-C, Single-stranded DNA-binding protein-interacting protein 1, SSB-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the SOSS-C family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to nuclear foci following DNA damage.
Protein: GPMA_STAAE
Sequence: MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: YEDK_ECOLI
Sequence: MCGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKVLLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSRMFKPLWQHGRAICFADGWFEWKKEGDKKQPFFIYRADGQPIFMAAIGSTPFERGDEAEGFLIVTAAADQGLVDIHDRRPLVLSPEAAREWMRQEISGKEASEIAASGCVPANQFSWHPVSRAVGNVKNQGAELIQPV
What is the function of this protein?
Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites (PubMed:30554877).  Recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue (PubMed:30554877, PubMed:31235915, PubMed:31504793).  May act as a protease: mediates autocatalytic processing of its N-terminal methionine in order to expose the catalytic cysteine (By similarity).
What are the official names of this protein?
Abasic site processing protein YedK.
What is the protein family that this protein belongs to?
Belongs to the SOS response-associated peptidase family.
Protein: TPC13_BOVIN
Sequence: MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMRDDPSTVNGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQSGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVAELNSVNQAGECVTTFGSRAYLQPMDTRQYLYCLKPKKEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFHITCKITNCSERTMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSSAIKVES
What are the official names of this protein?
Trafficking protein particle complex subunit 13.
What is the protein family that this protein belongs to?
Belongs to the TRAPPC13 family.
Protein: WBP11_RAT
Sequence: MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDMSSTSEDDGYPEDMDQDKHDDSTEDSDTDRSDAESDGDEFGHRDDSERDNTEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEEEDDDDSEDSEAEKPSQKQHKEDSHADGSSAASSQQQAPPQAVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGIRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPSLIQRPKADDASAATIEKKATATISAKPQITNPKAEVTRFVPTALRVRRENKGATAVPQRRSEEDSAVPVAKAAPRSGPSVPVSVQTKDDVYEAFMKEMEGLL
What is the function of this protein?
Activates pre-mRNA splicing.  May inhibit PP1 phosphatase activity (By similarity).
What are the official names of this protein?
WW domain-binding protein 11, WBP-11, Splicing factor that interacts with PQBP-1 and PP1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin (By similarity).
Protein: EF1A_METTP
Sequence: MADTKPHLNLAFIGHVDHGKSTLVGRMMYEMGAIDEHIIEQYRKEAAAKGKATFEFAWVMDSLKEERERGVTIDIAHQRFDTDKYYFTVVDCPGHRDFVKNMITGASQADAAVLVVAAPDGVMAQTKEHVFLARTLGVNQLIVAINKMDATEPPYDEKRYNEVKEEVGKLLRMVGYKIDEVPFIPVSAYNGDNVVKHSDRTKWYTGPTVLDALNALKEPQKPVNLPLRIPVQDVYSISGVGTVPVGRVETGVLKKGDKVIFEPAHVSGEVKSIEIHHQEIPEAYPGDNIGWNVRGIGKNDIRRGDVCGHVDNPPTVAKEFTAQIVVLQHPSAISAGYTPVFHCHTAQVACTITEIKAKLDPRTGSVKEQNPAFIKTGDAAIISVRPTKPMVIEKVKEIPQLGRFAIRDMGMTIAAGMCQNVTPR
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USA1_YEAST
Sequence: MSEYLAQTPCKFTIWSSEIDLIRTNLLVNAHPLSTVGRLLQYIHYQIYKQLRAIYQPEEQCTNSEIPHTPLNSINTYFLSYEGRELSATCLLKDITSSSHPDSNHFIRLQLEKRTSPSGSAFDLEYDMEGEFNSMNIQFEINTLSSQRIFNSMEPNLPIGTTLARLEKLALERIKDFEKSAGNLCGIKEDHSVSDLQGFIIKGKQTPMFLNYGSDSDYYKDLNLVDLIGIDFAPAHNSFFTFLFKMNHEQNSHIANDEERFVLEFISDATLSITQMNVKPDTTVKQVKDFICSVYTHSLNLRRNDIKLIYKGQLLHENNFAGNSSKISEYIKEPHEVKVHVQINQEYTESGPGFWNEVFNNPNIFQFMPPDTRSQSPVSFAPTQGRSPAAIRGEERGIPYVTESGNDIVPTDELYRKCIINGDEVVFIPVSELNPQSSYLSVIKGDYGEIKIPISSNDYRINGDNILLSPSAIEQLESALNFKIERPRDSTLLHPSGEHVRAADNTSSANDNNTVENDESAWNRRVVRPLRNSFPLLLVLIRTFYLIGYNSLVPFFIILEFGSFLPWKYIILLSLLFIFRTVWNTQEVWNLWRDYLHLNEIDEVKFSQIKEFINSNSLTLNFYKKCKDTQSAIDLLMIPNLHEQRLSVYSKYDIEYDTNTPDVGQLNLLFIKVLSGEIPKDALDELFKEFFELYETTRNMNTLYPQDSLNELLLMIWKESQKKDINTLPKYRRWFQTLCSQIAEHNVLDVVLRYIIPDPVNDRVITAVIKNFVLFWVTLLPYVKEKLDDIVAQRARDREQPAPSAQQQENEDEALIIPDEEEPTATGAQPHLYIPDED
What is the function of this protein?
Scaffold protein of the endoplasmic reticulum-associated degradation (ERAD) (also known as endoplasmic reticulum quality control, ERQC) pathway involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.  Component of the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M).  Has multiple functions in ERAD including recruitment of DER1 to the HRD1 ubiquitin ligase, and regulation of HRD1 activity.  Involved in oligomerization of HRD1 and in HRD1 autoubiquitination and degradation.
What are the official names of this protein?
U1 SNP1-associating protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RUVB_STAES
Sequence: MDKRMVDQEFHNEDTDLELSLRPTQLKQYIGQSSIKSNLEVFIKAAKLRQEPLDHVLLFGPPGLGKTTLSNIIANEMEVNIRTISGPSLERPGDLAAILSGLQPGDVLFIDEIHRLSSVVEEVLYPAMEDFFLDIIIGKGDEARSIRIDLPPFTLVGATTRAGSLTGPLRDRFGVHLRLEYYNENDLKEIITRTAEVLGTDIDKESALELARRSRGTPRIANRLLKRVRDFQQVNEDDQIYIETTKRALQLLQVDQHGLDYIDHKMMNCIINQYNGGPVGLDTIAVSIGEERVTIEDVYEPFLIQRGFLERTPRGRKATALAYEHFNTTNEKRE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: AZOR2_PHOPR
Sequence: MRVLYITANPKLIHHSVSLSLGELALQYYRELNPSHITDRLDLTTEEYPHLNSDTLSNFMNPHSNLATQSKIFKDYDKYIIVAPMWNLTVPSALKAYLDTVIIPNVLFRYTEQGTCEGLCGGKMIYIGARGGDYSHPPQSEYAFDDKYMEGIAKMIGLESYQSYVANAVGGYRRRSVAQWVEHAKYDIEQMVTSF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 2, Azo-dye reductase 2, FMN-dependent NADH-azo compound oxidoreductase 2, FMN-dependent NADH-azoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: PTH_METEP
Sequence: MRLIVGLGNPGARYARNRHNIGFMAVDEIARVHRAAPFRRRFQGEAAEVMLGSERAILLKPQTFMNESGRSVGEAQRFFKIPLADVIVLHDELDLAPAKLRVKLGGGNAGHNGLRSITALCGNEYRRVRLGIGHPGDKALVHAYVLNDFAKSEEPWVEDLCRATADHAPLLAAGEDASFQNKVHLAMAGRGWETVKTPAEAGKAKARDAN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_HISS2
Sequence: MKIVEVKHPLVKHKLGLMRVADITTKDFRELATEVGSLLTYEATSDLETEKVIIDGWCGAVEIDRIKGKKVTVVPILRAGLGMMDGVLEHVPSARISVVGMYRDEETLEPVPYFQKLASDLDERLAIVVDPMLATGGSMIATINLLKAKGCQHIKVLVLVAAPEGIKALEAVHPDVELYTASIDSHLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: CY176_POSPM
Sequence: MSLVLNRTDLLVVAGALFLTFLTTRFIRAAQRYHLPPGPTRIPLLGNLHQVPLHDQQKTFAEWVKKYGDIIYIQLLSKPFVIVSSVRAAQDLMEKRAVKYSDRPYFLLLCEFVMTRPLMIFMQHGDRWRRLRRWYQGSLENKSVLEGYRPVLRREIGRLLSSLAEAPQDFMSHIKRYNGAVMLDIAYGHRVTSAEDEFMVFADKTISTVTSLGSFAATLVDFFPILRYFPAWTPGSGFKKQALMAKEMWDEMEDIPYRKLRHEMGSDAVNRSFTTFMIGEVSHDGKLGADDEIDIKGSATLMYVAGSDTTMTTMTTFVLAMTLYPEVARKAQAEIDHVVGLSRLPGLDDKDSLPYLECIIKELYRWNPPVPLGVPHRLCVDDNYRGYDIPGGSMIVPNVWAMSRDPSLYPDTKTFRPERFEGLDAQAMKFRDPRKYIFGFGRRICPGRYLADSNVWLFLASVLASMDIGRAHDAAGHEIIPTPSFKDGIISHVEPFQCTIRPRSERAAQLIRESTGNTSA
What is the function of this protein?
Cytochrome P450 monooxygenase that is able to use delta(6)-protoilludene as a substrate to produce delta(6)-protoilludene-5-ol and an unidentified hydroxyprotoilludene (PubMed:30105900).  Is also able to use phenanthrene as a substrate for oxidation (PubMed:21938516).
What are the official names of this protein?
Cytochrome P450 monooxygenase 176.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ARFB_METRM
Sequence: MVELRVNAGNVKNPNVHKIGIIALGSHLENHGPALPIDTDAKIASHIAFQASLESGAKFLGVIYPAHELKEINHGIHVSLEDLTDEIVKVLKSAKKFLRISSVIIVNGHGGNLPIVTTLYDIEERTGLLITLNSKIIESEGPHGGSGELSMAKALGIIDESQVENQTNLEEYGEVGLYMFGEARRNDPNIEEGALDVEENGVYVDDVYGQELLKLAINSVLLDVEKQLDSHYGY
What is the function of this protein?
Catalyzes the hydrolysis of the formamide of 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy).
What are the official names of this protein?
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase, FAPy deformylase, Formamide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the creatininase superfamily. FAPy deformylase family.
Protein: FEMX_STAAR
Sequence: MEKMHITNQEHDAFVKSNPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
What is the function of this protein?
Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S. aureus peptidoglycan.  This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (GlcNAc-(beta-1,4)-N-acetylmuramic acid(-L-Ala-D-iGln-L-Lys-D-Ala-D-Ala)-pyrophosphoryl-undecaprenol), using glycyl-tRNA(Gly) as donor, in a ribosome-independent mechanism.  Involved in methicillin resistance (By similarity).
What are the official names of this protein?
Lipid II:glycine glycyltransferase, Factor essential for expression of methicillin resistance X.
What is the protein family that this protein belongs to?
Belongs to the FemABX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC21_PEA
Sequence: VVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQDVVHSEKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQMLCGIAYCHSHRVLHRDLKPQNLLIDRRTNCVKLADFGLARAFGIPVRTFTHEV
What is the function of this protein?
Plays a key role in the control of the eukaryotic cell cycle.  It is required in higher cells for entry into S-phase and mitosis.  Component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
What are the official names of this protein?
Cell division control protein 2 homolog 1, p34.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: K1B_METSE
Sequence: DSDCKDKLPACGEYRGSFCKLEKVKSNCEKTCGVKC
What is the function of this protein?
Has hemolytic activity (Ref. 1).  Inhibits voltage-gated potassium channels (Kv1/KCNA) (By similarity).
What are the official names of this protein?
U-metritoxin-Msn1a, U-MTTX-Msn1a, Metridin.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 1 potassium channel toxin family. Type 1b subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: SYS_CLONN
Sequence: MLDLKRIRNNPEEIKQIMQNRGEDFDNKLIDDVVALDERRRQILVEVEQLKSKRNSESSQIGKLKKEGKDTSAIMADMKKLSDDIKAFDVELNEVDEKIKYIMLRIPNIPNPNVPDGETDEDNIEIRKWGEPTKFDFESKAHWDIGTDLDILDFERGGKIAGSRFTVYKGLGARLERAIINYFLDMHTIDHGYTEILPPYMVNRDSMTGTGQLPKFEEDAFKVENNGYFLIPTAEVPVTNMYRNEILNGDDLPIKHAAYSACFRAEAGSAGRDTRGLVRQHQFNKVELVKFVKPEQSYDELEKLTNDAEDVLKGLGLPYRVVRICKGDLGFTAALKYDIEVWMPSYNRYVEISSCSNFEDFQARRANIRYKENGKGKPEFIHTLNGSGVAIGRTVAAILENYQNEDGTVTIPEALRPYMRNLDVIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_LEPBJ
Sequence: MADFEKVKSIIVEQLGVDESEVTPEAHFIDDLGADSLDTVELVMALEEEFGIEISDEDAEKIQTVGDVTKFIDNLKS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_ALKOO
Sequence: MKSLLLMMTFFTRIPVTYPYDYDEKDFIKGVKFLPVIGLLIGILMYLPTLLAPYIHRPIIIVSIWALYFLITGGLHIDGLADTFDGIFSYRSKEEMLRIMKDSRIGAFGVLGILWLLILNLTLAYYTENMLLLLVPVVGRASAVFAASRTIYARSEGMGGAFIESCRTKEGVISIAFSLLLGSMVSIKGAIIPMGITFLGVAMLTKKISKILGGMTGDTIGATIEISQTLFMLSAYLLKSIII
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARAB_STAA3
Sequence: MSYSIGIDYGTASGRVFLINTTNGQVVSKFVKPYTHGVIESELNGLKIPHTYALQNSNDYLEIMEEGISYIVRESKIDPDNIVGIGIDFTSSTIIFTDENLNPVHNLKQFKNNPHAYVKLWKHHGAYKEAEKLYQTAIENNNKWLGHYGYNVSSEWMIPKIMEVMNRAPEIMEKTAYIMEAGDWIVNKLTNKNVRSNCGLGFKAFWEEETGFHYDLFDKIDPKLSKVIQDKVSAPVVNIGEAVGKLDDKMAQKLGLSKETMVSPFIIDAHASLLGIGSEKDKEMTMVMGTSTCHLMLNEKQHQVPGISGSVKGAIIPELFAYEAGQSAVGDLFEYVAKQAPKSYVDEAENRNMTVFELMNEKIKHQMPGESGLIALDWHNGNRSVLSDSNLTGCIFGLTLQTKHEDIYRAYLEATAFGTKMIMQQYQDWHMEVEKVFACGGIPKKNAVMMDIYANVLNKKLIVMDSEYAPAIGAAILGAVSGGAHNSINDAVDAMKEPILYEINPEAEKVQRYETLFKAYKALHDIHGYKKANIMKDIQSLRVEG
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.