PharMolix/UniProtQA huggingface dataset:
Protein: ERA_PSESM
Sequence: MNDTTATRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGTVQAIYVDTPGMHKNGEKALNRYMNKTASAALKDVDVVIFVVDRTRWTDEDQMVLERVQYVQGPVILAINKTDRIEDKSDLMPHLEWLQGQLPNASIVPISAQHGHNLEALESLIASHLPENDHFFPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQQGRTLHIHALILVERDGQKKIIIGDKGDRIKRIGSDARRDMEVLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: NFYA5_ARATH
Sequence: MQVFQRKEDSSWGNSMPTTNSNIQGSESFSLTKDMIMSTTQLPAMKHSGLQLQNQDSTSSQSTEEESGGGEVASFGEYKRYGCSIVNNNLSGYIENLGKPIENYTKSITTSSMVSQDSVFPAPTSGQISWSLQCAETSHFNGFLAPEYASTPTALPHLEMMGLVSSRVPLPHHIQENEPIFVNAKQYHAILRRRKHRAKLEAQNKLIKCRKPYLHESRHLHALKRARGSGGRFLNTKKLQESSNSLCSSQMANGQNFSMSPHGGGSGIGSSSISPSSNSNCINMFQNPQFRFSGYPSTHHASALMSGT
What is the function of this protein?
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity).  Involved in the blue light (BL) and abscisic acid (ABA) signaling pathways.
What are the official names of this protein?
Nuclear transcription factor Y subunit A-5, AtNF-YA-5.
What is the protein family that this protein belongs to?
Belongs to the NFYA/HAP2 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPG_CORU7
Sequence: MANLRELRSRIKSVNSTKKITKAQELIATSRITKAQARVDASQPYAHEITKVIERLASASSLDHKMIREPKDPKRAAILVVSSDRGMCGGYNNNVFKTTAELRKLLEDEGKEVVLYVLGSKGVTYYNFRNENISGSWTGHSQDPVYAETLNLRNHLIGGFLAGSEGTVDVVDGVNAEGDQVPGFDEVHMVYTEFHSMLSQVPKAHRLLPIKTVVEEEKMELGSDMVSDSADQVSAEVDFEPDADTLLANLLPQYVSRGIFAALLEAAASESAARRTAMSAATDNASELVENLSRIANQARQAQITQEITEIVGGASALGDSGESD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PAX6_CHICK
Sequence: QMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ
What is the function of this protein?
May be a transcription factor with important functions in eye and nasal development.
What are the official names of this protein?
Paired box protein Pax-6.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PNTH_STRAE
Sequence: MTDTFSDYADCTPLLDDREALDRFYDEHGYVYLRGVLDRELVRTTAEQMLQGLIALGHAAPGTTLDTLTIESYEAVDEVAMHDHVRYDDLWNHPSTLKVWEKVFGEPVFVFKSTTIRYYPSAPDSAEPSFLTPLHQDGFYIGPNKDFRTAWIPLLPTTRGTGGVAIADGSHKKGPREHVLTENFRRFGHAVRGIPPAEFGADEELLFSPMEPGDVLLFHAFMCHKSLPNVSVDPAGMRMSMDTRIQPASSHRGFNALTPWPESAKDASKGIMSKITGTPTTAE
What is the function of this protein?
Catalyzes the conversion of 1-deoxypentalenic acid to 11-beta-hydroxy-1-deoxypentalenic acid in the biosynthesis of pentalenolactone antibiotic.
What are the official names of this protein?
1-deoxypentalenic acid 11-beta-hydroxylase, Pentalenolactone biosynthesis protein H.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: RIBA_ECO45
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTEAGINIIERVPLIVGRNPNNEHYLDTKAEKMGHLLNK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: YQJQ_BACSU
Sequence: MKHIAGKRIWITGASGGLGERIAYLCAAEGAHVLLSARREDRLIEIKRKITEEWSGQCEIFPLDVGRLEDIARVRDQIGSIDVLINNAGFGIFETVLDSTLDDMKAMFDVNVFGLIACTKAVLPQMLEQKKGHIINIASQAGKIATPKSSLYSATKHAVLGYSNALRMELSGTGIYVTTVNPGPIQTDFFSIADKGGDYAKNVGRWMLDPDDVAAQITAAIFTKKREINLPRLMNAGTKLYQLFPALVEKLAGRALMKK
What are the official names of this protein?
Uncharacterized oxidoreductase YqjQ.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: YDIV_SALCH
Sequence: MIASLDELYHSELFFLPVMDENAWLVGLAIIATFAAEDGAVRMPTELVAPRLSVEEQYCLFVEKLALLETCQHFFIQHKLIAWLNLPPAISDLLLLDSELFSRAARFPFLELAINENYPGLNQGKNNETLANLAMHFPLMLANFGSGEASTKAIFDGLFKRVMLDKNFIQQRAEMISFEPFMHAIVAQISSSCESLMIAGIDTEAMFARAAPLGFSAFQGGLWPPVPVSQLIKLVQR
What is the function of this protein?
Acts as an anti-FlhC(2)FlhD(4) factor by binding to FlhD, decreasing its ability to bind DNA, and thus negatively regulates expression of flagellar class II operons, decreasing motility in nutrient-poor medium.  Required for resistance to host phagocyte oxidase (By similarity).
What are the official names of this protein?
Anti-FlhC(2)FlhD(4) factor YdiV.
What is the protein family that this protein belongs to?
Belongs to the YdiV family.
Protein: TGA22_ORYSJ
Sequence: MADASSRTDTSTVLDTDDKNQMVDGQSGAIVPSNSSDRSDRSDKPMDQKVLRRLAQNREAARKSRLRKKAYVQQLESSKLKLASLEQEINKARQQGIYISSSGDQTHAMSGNGAMTFDLEYARWLEEQNKQINELRTAVNAHASDSDLRLIVDGIMAHYDEIFRLKGVAAKADVFHILSGMWKTPAERCFLWLGGFRSSELLKLLVNQLEPLTEQQLLGLSNLQQSSQQAEDALSQGMEALQQSLADTLAGSLGPSGSSGNVANYMGQMAMAMGKLGTLENFLRQADNLRQQTLHQMQRILTIRQAARALLAIHDYFSRLRALSSLWLARPRE
What is the function of this protein?
Transcriptional regulator involved in defense response.
What are the official names of this protein?
Transcription factor TGA2.2, OsNIF1, OsbZIP1, bZIP transcription factor 28, OsbZIP28.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NAL11_HUMAN
Sequence: MAESDSTDFDLLWYLENLSDKEFQSFKKYLARKILDFKLPQFPLIQMTKEELANVLPISYEGQYIWNMLFSIFSMMRKEDLCRKIIGRRNRNQEACKAVMRRKFMLQWESHTFGKFHYKFFRDVSSDVFYILQLAYDSTSYYSANNLNVFLMGERASGKTIVINLAVLRWIKGEMWQNMISYVVHLTAHEINQMTNSSLAELIAKDWPDGQAPIADILSDPKKLLFILEDLDNIRFELNVNESALCSNSTQKVPIPVLLVSLLKRKMAPGCWFLISSRPTRGNNVKTFLKEVDCCTTLQLSNGKREIYFNSFFKDRQRASAALQLVHEDEILVGLCRVAILCWITCTVLKRQMDKGRDFQLCCQTPTDLHAHFLADALTSEAGLTANQYHLGLLKRLCLLAAGGLFLSTLNFSGEDLRCVGFTEADVSVLQAANILLPSNTHKDRYKFIHLNVQEFCTAIAFLMAVPNYLIPSGSREYKEKREQYSDFNQVFTFIFGLLNANRRKILETSFGYQLPMVDSFKWYSVGYMKHLDRDPEKLTHHMPLFYCLYENREEEFVKTIVDALMEVTVYLQSDKDMMVSLYCLDYCCHLRTLKLSVQRIFQNKEPLIRPTASQMKSLVYWREICSLFYTMESLRELHIFDNDLNGISERILSKALEHSSCKLRTLKLSYVSTASGFEDLLKALARNRSLTYLSINCTSISLNMFSLLHDILHEPTCQISHLSLMKCDLRASECEEIASLLISGGSLRKLTLSSNPLRSDGMNILCDALLHPNCTLISLVLVFCCLTENCCSALGRVLLFSPTLRQLDLCVNRLKNYGVLHVTFPLLFPTCQLEELHLSGCFFSSDICQYIAIVIATNEKLRSLEIGSNKIEDAGMQLLCGGLRHPNCMLVNIGLEECMLTSACCRSLASVLTTNKTLERLNLLQNHLGNDGVAKLLESLISPDCVLKVVGLPLTGLNTQTQQLLMTVKERKPSLIFLSETWSLKEGREIGVTPASQPGSIIPNSNLDYMFFKFPRMSAAMRTSNTASRQPL
What is the function of this protein?
Involved in inflammation.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 11, Nucleotide-binding oligomerization domain protein 17, PAAD-and NACHT domain-containing protein 10, PYRIN-containing APAF1-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
Protein: THIG_BACC3
Sequence: MLNIGPFSFHSRLLLGTGKFPDFDVQQKAIDVSEAEVLTFAVRRMDIFDAKQPNLLEKLDVKKYTLLPNTAGAKNAEEAVRIAKLAKASGLCDMIKVEVIGDDRTLLPDPVETLKASEMLLEEGFIVLPYTSDDVVLARKLQELGVHAIMPGASPIGSGLGIVNPLNLSFIIEQATVPVIVDAGVGSPADAAFAMELGADGVLLNTAVSGAKDPIKMAQAMKLSIEAGRLGFEAGRIARKRCATASSPLEGMSVVE
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNF7_DEBHA
Sequence: MWNYLFGGNKQQKKEYPKKAIVELREHIQMLNKKRSHLESQIADQDALARKYITTNKALAKNALKRKKGYEANLMKIENQIDSLETQLTSIEGANLNLETMKAMKQGAQAMKQIHGEYDVDKVENTMDDIREQVELADEISEAISRPVGTEFVDEDELDEELAMLQEEEKEHKQQTPAQKAPVAKVSAPEEEMPDFPTVNKNKPAASTEDDEDEEALKALQAEMGL
What is the function of this protein?
Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB).  Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity).
What are the official names of this protein?
Vacuolar-sorting protein SNF7, Vacuolar protein-sorting-associated protein 32.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: ACYP_GEOMG
Sequence: MTMKIRAIVTVKGLVQGVAFRHHTVLQGNQLRVTGWVKNLPNGDVQGCFEGDETDVQALVEWCHHGPSRARVDRVIVERKSFRGEFDTFDVRY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: CAPSD_CMVSI
Sequence: MGEPTPTPAATYSAADPTSAPKLADLAAIKYSPITSSIATPEEIKAITQLWVNNLGLPADTVGTAAIDLARAYADVGASKSATLLGFCPTKPDVRRAALAAQIFVANVTPRQFCAYYAKVVWNLMLATNDPPANWAKAGFQEDTRFAAFDFFDAVDSTGALEPAECSAAPLTATCALDREVRRPCPSAYPERQPHHQHCRGHQGPSWLHQHSLRSACTPY
What is the function of this protein?
Required for genome encapsidation.  Forms ribonucleoprotein complexes along with TGB1 helicase and viral RNA.
What are the official names of this protein?
Coat protein, Capsid protein, CP.
What is the protein family that this protein belongs to?
Belongs to the potexvirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: EFP_METC4
Sequence: MKVIASTLRKGNVVDKDGKLYVILTAENIHPGKGTPVTQLDMRRITDGVKISERYRTTEQVERAFVEDRDHTFLYQDGEGYHFMNPESYEQIAVPADVVGDAAPYLQEGMTVTLSTHNGVPLTIELPQRMTFEIVETEPVTKGQTASSSYKPALLSNGVKTSVPPHVSTGTRVVIMTADGSYVERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_DICT6
Sequence: MAKKKRTRGPKREKRIVPVGVAHINSTFNNTIVTITDPEGNVLTWGSGGTAGFKGTKKGTPFAAQLAAEMAAKKAISEYGMKKVDVLVKGPGPGRETAIRALQAAGLEISLIKDVTPIPHNGCRPPRRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: APOE_CAVTS
Sequence: MKVLWAALVVTLLAGCRADVEPEVEVREPAVWQSGQPWELALSRFWDYLRWVQTLSDQVQEELLSNQVTQELTLLIEDTMKEVKDYKAELEKELGPVAEDTKARLAKELQAAQARLGADMEEVRNRLSQYRSEVQAMLGQSSEELRARLTSHLRKMRKRLQRDIDELQKRMAVYKAGAQEGAERGVSAIRERLGSLIEQGRLQALTSQPLQERAQAWGEQMRGRLEKVGSQARDRLEEVREQMEEVRVKVEEQAEAFQARLKSWFEPMMEDMRRQWAELIQKVQVAVGASTSAPSQEP
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: APA11_ONCMY
Sequence: MKFLALALTILLAAGTQAFPMQADAPSQLEHVKAALSMYIAQVKLTAQRSIDLLDDTEYKEYKMQLTQSLDNLQQYADATSQSLAPYSEAFGTQLTDATAAVRAEVMKDVEELRSQLEPKRAELKEVLDKHIDEYRKKLEPLIKEHIELRRTEMEAFRAKMEPIVEELRAKVAINVEETKTKLMPIVEIVRAKLTERLEELRTLAAPYAEEYKEQMIKAVGEVREKVSPLSEDFKGQVGPAAEQAKQKLLAFYETISQAMKA
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).
What are the official names of this protein?
Apolipoprotein A-I-1, Apo-AI-1, ApoA-I-1, Apolipoprotein A1-1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: NCAP_MPV15
Sequence: MSLDRLKLNDVSNKDSLLSNCKYSVTRSTGDVTSVSGHAMQKALARTLGMFLLTAFNRCEEVAEIGLQYAMSLLGRDDSIKILREAGYNVKCVDTQLKDFTIKLQGKEYKIQVLDIVGIDAANLADLEIQARGVVAKELKTGARLPDNRRHDAPDCGVIVLCIAALVVSKLAAGDRGGLDAVERRALNVLKAEKARYPNMEVKQIAESFYDLFERKPYYIDVFITFGLAQSSVRGGSKVEGLFSGLFMNAYGAGQVMLRWGLLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKQGGEAGFYHIRNNPKASLLSLTNCPNFTSVVLGNAAGLGIIGSYKGAPRNRELFDAAKDYAERLKDNNVINYSALNLTAEERELISQQLNIVDDTPDDDI
What is the function of this protein?
Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases.  RNA replication depends on the availability of soluble nucleoprotein.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Localizes in cytoplasmic inclusion bodies.
Protein: RECA_NITEC
Sequence: MDENKNKALTAALAQIEKQYGKGSIMRLGDSDVAKDIQVVSTGSLSLDIALGVGGLPRGRIIEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDPQYAQKIGVNVQELLISQPDNGEQALEITDMLVRSGSVDIVVIDSVAALTPRAEIEGEMGEPQMGLQARLMSQALRKLTANIKRTNTTVIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGSIKRGEEIVGNETRVKVVKNKVAPPFKQADFAILYGEGISRESEIIELGVLHKLIEKAGAWYSYNGEKIGQGRDNVRDYLKEHKDLAHEIEQKIRAAVDLAETNNRTVPPSPSE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF1_PARJU
Sequence: MSWQAYVDDHLMCDVGDGNTPASAAIIGHDGSVWAQSANFPQLKPEEVTGIMNDFNEAGFLAPTGLFLGGTKYMVIQGESGAVIRGKKGSGGATLKKTGQAIVIGIYDEPMTPGQCNLVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-1, Pollen allergen Par j 3.0101.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PYRE_STRR6
Sequence: MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLAYPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDHGAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKADKNFADAGVKLVTLSNYSDLIHLAQEEGYITPEGLYLLKRFKEDQENWQEG
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CLPX_SALCH
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PRB3_HUMAN
Sequence: MLLILLSVALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGSPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ
What is the function of this protein?
Acts as a receptor for the Gram-negative bacterium F. nucleatum.
What are the official names of this protein?
Basic salivary proline-rich protein 3, Parotid salivary glycoprotein G1, Proline-rich protein G1.
What are the subcellular locations of this protein?
Secreted.
Protein: ACPS_PECCP
Sequence: MAILGLGTDIVEIARIEAVIERSGERLARRVLTDAEWAHYQQHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPCLRFFAKAAELAEQMGVRHVHVTLADERRYACATVIVES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_STRE4
Sequence: MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIVIDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRAHVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERLKTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGPFPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLSGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPENARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG1_LEGPA
Sequence: MDGKVGNTATGCPVIHGGMTSAETSNTAWWPNALNLDILHQHDTKTNPMGKDFNYREEVKKLDFVAFKKDLHALMTDSQAWWPADWGHYGGLMIRMSWHAAGSYRVADGRGGAGTGNQRFAPLNSWPDNVNLDKARRLLWPIKKKYGNKISWADLIVLAGTIAYESMGLKTFGFGFGREDIWHPEKDVYWGSEQEWLGAKRYDDKDRQSLETPLAAVQMGLIYVNPEGVNGQPDPLRTAQDVRVTFGRMAMNDEETVALTAGGHTVGKCHGNGNAKFLGPEPEAADIEDQGLGWINKTTRGIGRNTVSSGIEGAWTTHPTQWDNGYFYLLLNYDWELKKSPAGAWQWEPIHIKEEDKPVDVEDPAIRHNPIMTDADMAIKMDPVYRKIAERFYKDPDYFAEVFARAWFKLTHRDMGPKTRYIGPDVPKEDLIWQDPVPSGNRAYDIAAAKAKIAASNLTIGEMVSTAWDSARTFRGSDKRGGANGARIRLKPQKDWEGNEPQRLTKVLRILEGIAADTGASVADVIVLAGNVGIEKAAKAAGFDIIVPFAPGRGDATDDMTDAESFDVLEPLHDGYRNWLKKAYDVRPEELMLDRTQLMGLTAHEMTVLVGGLRVLGTNHNNTQHGVFTDRVGVLTNDFFVNLTDMANVWIPSKDNLYEIRDRKAGNIKWTATRVDLVFGSNSILRSYAEVYAQDDNKGKFIQDFVAAWTKVMNADRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 1, CP 1, Peroxidase/catalase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: VRPO_LAMBD
Sequence: MTNTAKILNFGRGNFAGQERNVADLDDGYARLSNMLLEAYSGADLTKRQFKVLLAILRKTYGWNKPMDRITDSQLSEITKLPVKRCNEAKLELVRMNIIKQQGGMFGPNKNISEWCIPQNEGKSPKTRDKTSLKLGDCYPSKQGDTKDTITKEKRKDYSSENSGESSDQPENDLSVVKPDAAIQSGSKWGTAEDLTAAEWMFDMVKTIAPSARKPNFAGWANDIRLMRERDGRNHRDMCVLFRWACQDNFWSGNVLSPAKLRDKWTQLEINRNKQQAGVTASKPKLDLTNTDWIYGVDLKTSPHRWLTLTVSRCVGSPTTCRNSTTKSRRYSR
What is the function of this protein?
Necessary for the bidirectional replication of DNA.  It interacts with the ori (origin of replication) region of the genome during the initiation of replication.
What are the official names of this protein?
Replication protein O.
What is the protein family that this protein belongs to?
Belongs to the phage O protein family.