PharMolix/UniProtQA huggingface dataset:
Protein: 5HT2B_CAVPO
Sequence: CNQSTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYKATKSVKTVRKCSNKIYFRNPMTENSKFFMKHGMRNGINSTMYQSPVRL
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.  Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores.  Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity.  May play a role in the perception of pain.  Plays a role in the regulation of behavior, including impulsive behavior.  Required for normal proliferation of embryonic cardiac myocytes and normal heart development.  Protects cardiomyocytes against apoptosis.  Plays a role in the adaptation of pulmonary arteries to chronic hypoxia.  Plays a role in vasoconstriction.  Required for normal osteoblast function and proliferation, and for maintaining normal bone density.  Required for normal proliferation of the interstitial cells of Cajal in the intestine (By similarity).
What are the official names of this protein?
5-hydroxytryptamine receptor 2B, 5-HT-2B, 5-HT2B, Serotonin receptor 2B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: CHRD1_PIG
Sequence: MALLCYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIAGCTKGRHNSEKPPEPVKPEVKTTEKKELSELKPRFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEENKKEEDSDEIKVGTSCKNGGCSKTYQGPQSLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTTGKHTWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSQVVANSTLLNVHIVFEGEKEFHQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPAAKNQEKQKEDTAE
What is the function of this protein?
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2.  Proposed to act as co-chaperone for HSP90.  May play a role in the regulation of NOD1 via a HSP90 chaperone complex.  In vitro, has intrinsic chaperone activity.  This function may be achieved by inhibiting association of ROCK2 with NPM1.  Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling (By similarity).  Involved in stress response.  Prevents tumorigenesis (By similarity).
What are the official names of this protein?
Cysteine and histidine-rich domain-containing protein 1, CHORD domain-containing protein 1, Chp-1, Morgana.
Protein: RR12_THAPS
Sequence: MPTIQQLVRLRRIQITKKTKSPALVNCPQRRGVCTRVYTTTPKKPNSAIRKVARVRLTSGFEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDSGGVKDRTQRRSKYGVKKPKS
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIC10_CAEEL
Sequence: MAPGASAPAASRSEDEVGQKIDRCFADSLLKVTGGVAIGIVASVAFFKSRSWPIWFGSGVGLGTGWSNCRHDFASPYVLHGKRVPAGQDSQGKPAYNIITEQHKQ
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit Mic10.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Note=The C-terminus is located in the intermembrane space, while the location of the N- terminus has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space (By similarity).
Protein: PURT_ACIAC
Sequence: MPITLGTPLSPSATKVMLLGSGELGKEVLIALHRLGVETTAVDRYDNAPGQQVAHHARTITMSDPAQLKALIEAERPHLVVPEIEAIATPMLEELEAAGTVRVIPTARAARLTMDREGIRRLAAETLGLPTSPYRFCDSAEELQAAIDGTDGQPAIGFPCVVKPVMSSSGKGQSKLDGPADVQKAWDYAMAGGRVSHGRVIVEGFIDFEYEITLLTVRARAADGSIQTSFCEPIGHKQVSGDYVESWQPQPMPPLALQRARDIARAVTDDLGRGLDGQPSGQGLFGVELFVKGDEVWFSEVSPRPHDTGLVTLATQHQSEFELHARAILGLPVDTSLRNPGASAVIYGGVDAQGIAFDGVDEALAVPGTDLRLFGKPESFARRRMGVAVARADDVDTARANARLAAGRVRPRAA
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RNPA_BACC7
Sequence: MKKKHRIKKNDEFQTVFQKGKSTANRQFVVYQLDKEEQPNFRIGLSVSKKIGNAVVRNRIKRMIRQSITELKDEIDSGKDFVIIARKPCAEMTYEELKKSLIHVFKRSGMKRIKK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RPOB_MYXXD
Sequence: MPTQIQNNFRVRKTFAKIAKIIDIPNLINIQKQSYEKFLQADIAADKREDLGLQGVFKSVFPIRDFNETSSLEFVSYHLERPKYDVDECHQRGMTYSAPIKVVVRLVVWDKDEETGAQSIRDVKEQEVYFGEIPLMTQNGTFIINGTERVVVSQLHRSPGAFFDHDKGKSHSSGKLLYNARIIPYRGSWIDFEFDHKDLLYVRIDRRRKLPATVLIRALGAVPDTAKKNPLEFKGSTEEILNYYYATETIYLHSAEEFEKSVELELLPGQRATRDIKAKTGELIVKKNRKFTRAAIKKLEAAKMKTLPIDADELFTKVSAYDVVEETNGVVLLECNEEVTQEKVDELLKHGIKEFKVLFIDNLNVGPYLRETLMLDKLETPEQSIMEIYRRLRPGDPPTPETAINLFTNLFFNPERYDLSKVGRLKLNFKFGLEEPLDGQILTKRDILEVIRYLIDLKNGKGTIDDIDHLGNRRVRAVGELLENQYRIGLVRMERAIKERMSLQEIETLMPHDLINAKPVTAVIKEFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLIASLSTYARVNEFGFVETPYRKVEAGVVTNDVAFYSALEEEKHTIAQANAETDKKGKFANALVSSRRGGEFVQARAEDVDLMDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLRTAAPLVGTGIESIVARDSGVTCVARRDGIVESVDAGRIVVKADVPASLSDVTSEVDIYNLLKYQRSNQNTCLNQKPIISKGDRVMKGDVIADGPATETGELALGQNVVVAFMPWQGYNFEDSILISERILKDDVFTSIHIEEFECIARDTKLGKEEITRDIPNVGEEALKDLDESGIIRIGAEVKPGDVLVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDSSLRVPPGVVGTVINAKVFSRKGVEKDERAKQIESMEEAKLLKDQNDEIKVLQDSAFGRIRGLVRTKEVQGKLVDDKGKILLKKGDILDDELLSTVPYKYWGEISVGDPLDSRLRDILRNLEETKEAVKLAFGEKIARIKKGDELPPGVIKMVKVYVAIKRKLAVGDKMAGRHGNKGVVSRILPEEDMPYLEDGRPVDIVLNPLGVPSRMNIGQILETHLGWAAKGTGEALQRYVEANWSSDAIKERLKVIYSDPAFGEFLDKLDDEEIKQLCLRSKRGIHVATPVFDGAQETEIHALLDEGQLPRSGQMVLFDGRTGEPFDQNVTVGVMYMLKLHHLVDEKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYTLQEFLTVKSDDVVGRTRMYEAIVKGDNVLESGLPESFNVLLKELQSLALDVELLESAPPERQRSFGGDFLGGGDGEERKTGTEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: AMYR_DROTE
Sequence: MFKLALTLTLCLAGSLSLAQHNPHWWGNRNTIVHLFEWKWSDIAQECESFLGPRGFAGVQVSPVNENIIAAGRPWWERYQPISYKLTTRSGNEEEFGDMVRRCNDVGVRIYVDVLLNHMSGDFDGVVVGTAGTEAEPREKSFPGVPYTAQDFHPTCEITDWNDRFQVQQCELVGLKDLDQSSDWVRSKLIEFLDHLIELGVAGFRVDAAKHMASEDLEYIYSSLSNLNIDHGFPHNSRPFIFQEVIDHGHETVSRDEYKDLGAVTEFRFSEEIGNAFRGNNALKWLQSWGTGWGFLPSGQALTFVDNHDNQRDAGAVLNYKSPKQYKMATAFHLAYPYGISRVMSSFAFDDHDTPPPQDAQERIVSPEFDEDGACVNGWICEHRWRQIYAMVGFKNAVRDTEVTGWWDNGDNQISFCRGNKGFLAINNNLYDLSQDLNTCLPEGTYCDVISGSLIDGSCTGKSVTVNEYGFGYIHIGSDDFDGVLALHVDARV
What are the official names of this protein?
Alpha-amylase-related protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH2_FRAT1
Sequence: MIILGIDEAGRGPLSGPVVAAGVILDQDKIIDGLADSKKLTEKKRQSLYQQIITHAKAYTIVEISPQQIDELNILQATLKAMHQVANNLERQFDKVLVDGNKLPNWDYNSEAIVKGDSKIIEISAASILAKVHRDNICLEHDRLYPQYGFAKHKGYPTKEHLENIKKYGVLDIHRKSYKPVQVLLNE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM177_XENLA
Sequence: MSSPFLWRFLSFTQKYRGTLLAVSSVGLFAANISYHVAPEQTFRKLYQGWSKGEPVQLTAKLQGLFQEVLEETHMGVTSSYVPFSAFGFHPVSAGIPWLPSGCLIGIPFNYNDTEQDGVGIADRVLLINGKEVDWSSDAGTHLRQALNLSLDAQKFSLAREVFYAQGNSPIIQASAAPVCLSGICLSSVAIKQLLGLYSGPILLRGVYNMAVVVLGFAGYFLCSDAVSQWLDYQSDRKVAAVSKSYATGGIEFYEKILAQNRILRTLMGKQGETMYSPSGNLFPNDYLRLKNAPYTSRRDRIKNALLQME
What is the function of this protein?
Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.
What are the official names of this protein?
Transmembrane protein 177.
What is the protein family that this protein belongs to?
Belongs to the TMEM177 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RIC7_ARATH
Sequence: MQLGMSSTKMKSLLKGLRYISQVFAIEGEKEEEMQIGNPTDVKHVAHIGWDGPSDNATAPSWMNDFKSSPVMESIQGLGEDDSSVKCQSEFGGRTRDLPKLPKSTRKSSSEKGSPTKERSDKTKRRTSNKGTSSSRRTKDEDSTSSSRRTTKDEDSSLSQHSAGLPEVPKKSKRKKSKEAGNGGSSRSSRISEADYMSDTGSDRSMPQFEDDRNGF
What is the function of this protein?
Functions as downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family.  Participates in the propagation of ROP GTPase signals in specific cellular responses.  Functions as downstream effector of active ARAC4/ROP2 GTPase which is involved in the prevention of excessive stomatal opening upon light stimulation.  Is involved in pollen tube growth regulation through its interaction with ARAC11/ROP1.
What are the official names of this protein?
CRIB domain-containing protein RIC7, ROP-interactive CRIB motif-containing protein 7, Target of ROP protein RIC7.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein. Note=In guard cells in the dark localizes predominantly in the nucleus, but upon light irradiation, it is found at the plasma membrane and in the cytoplasm.
Protein: PEG10_HUMAN
Sequence: MTERRRDELSEEINNLREKVMKQSEENNNLQSQVQKLTEENTTLREQVEPTPEDEDDDIELRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLRQGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCIHIERRLARAAAARKPRSPPRALVLPHIASHHQVDPTEPVGGARMRLTQEEKERRRKLNLCLYCGTGGHYADNCPAKASKSSPAGKLPGPAVEGPSATGPEIIRSPQDDASSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAIDGRPIASGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQPVRYYYVQNVYTPVDEHVYPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPNGAQVLQVKRGWKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIPGYQTYPTYAAYPTYPVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPPPSYSTL
What is the function of this protein?
Retrotransposon-derived protein that binds its own mRNA and self-assembles into virion-like capsids (PubMed:34413232).  Forms virion-like extracellular vesicles that encapsulate their own mRNA and are released from cells, enabling intercellular transfer of PEG10 mRNA (PubMed:34413232).  Binds its own mRNA in the 5'-UTR region, in the region near the boundary between the nucleocapsid (NC) and protease (PRO) coding sequences and in the beginning of the 3'-UTR region (PubMed:34413232).  Involved in placenta formation: required for trophoblast stem cells differentiation (By similarity).  Involved at the immediate early stage of adipocyte differentiation (By similarity).  Overexpressed in many cancers and enhances tumor progression: promotes cell proliferation by driving cell cycle progression from G0/G1 (PubMed:12810624, PubMed:16423995, PubMed:26235627, PubMed:28193232).  Enhances cancer progression by inhibiting the TGF-beta signaling, possibly via interaction with the TGF-beta receptor ACVRL1 (PubMed:15611116, PubMed:26235627, PubMed:30094509).  May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter; additional evidences are however required to confirm this result (By similarity).
What are the official names of this protein?
Retrotransposon-derived protein PEG10, Embryonal carcinoma differentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, MEF3-like protein 1, Paternally expressed gene 10 protein, Retrotransposon gag domain-containing protein 3, Retrotransposon-derived gag-like polyprotein, Ty3/Gypsy-like protein.
What are the subcellular locations of this protein?
Extracellular vesicle membrane. Cytoplasm. Nucleus. Note=Forms virion-like extracellular vesicles that are released from cells (PubMed:34413232). Detected predominantly in the cytoplasm of breast and prostate carcinomas, in hepatocellular carcinoma (HCC) and B-cell chronic lymphocytic leukemia (B-CLL) cells and in the Hep-G2 cell line (PubMed:12810624).
Protein: RRF_MYCGA
Sequence: MEFKTYSDFFDKNANSIINWFEGELAKVRSGRANLKILDNVRAEYYGEQTPLIEMASLSIPEPREILIKPYEKSSVNLIQAALLKANLNLTPVVDGDKIRIKLPLLTEENRKENVKKVKAVGEKAKQEVRFIRRDTLNKIKSDKIADKDLNKYFEEQVDKITKKYIDQIDSILAKKEKDLLSL
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_STRPM
Sequence: MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPASYVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNGDFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFSTAGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEATKTDSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPI2_CWPXB
Sequence: MDIFREIASSMKGENVFISPPSISSVLTILYYGANGSTAEQLSKYVEKEADKNKDDISFKSMNKVYGRYSAVFKDSFLRKIGDNFQTVDFTDCRTVDAINKCVDIFTEGKINPLLDEPLSPDTCLLAISAVYFKAKWLMPFEKEFTSDYPFYVSPTEMVDVSMMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNLTDTNFKKWCDSMDAMFIDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMCNSDVSVDAMIHKTYIDVNEEYTEAAAATCALVADCASTVTNEFCADHPFIYVIRHVDGKILFVGRYCSPTTN
What is the function of this protein?
Viral serpin that inhibits both cysteine and serine proteinases involved in the regulation of host inflammatory and apoptosis processes (PubMed:10975564).  Major anti-apoptotic protein which inhibits both intrinsic and extrinsic pathways and strongly cleaves host CASP1 and CASP8 but is a rather poor inhibitor of host CASP3 (PubMed:10903953).  Prevents the proteolytic activity of host interleukin-1-beta converting enzyme (ICE) and ICE-like enzymes.  Can also block apoptosis through host tumor necrosis factor (TNF) receptor.
What are the official names of this protein?
Serine proteinase inhibitor 2, Serp-2, Serpin-2, Cytokine response modifier protein A, Hemorrhage-inducing 38 kDa protein, ICE inhibitor.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Poxviruses subfamily.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: SNF7_CRYNJ
Sequence: MSGWMSYFTGRKDTRESARDAIVGLRQQLLMLEKKEEFLQKKIEEEMKKAKANATGNKRLAMAALRQKKAHENELDRIAGTRLTLETQVNAIESANLNAETMVAMKKGADALKGIHSNLTAEGVDATMDKIREQMDLTNDISDAISNPVGMGIVLDEDDLKEELEALEQEQLDDRLAGADRVPSHLPASPVGQTTGRAAVEEDEDDEEAQLRKLQAELAM
What is the function of this protein?
Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB).  Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity).
What are the official names of this protein?
Vacuolar-sorting protein SNF7, Vacuolar protein-sorting-associated protein 32.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: LAMB1_YERP3
Sequence: MITLRKLPIALAVAAGVLSTQAMAVDFHGYARSGIGWTASGGEQQCFQTTGAQSKYRLGNECETYAELKLGQELWKEGDKSFYLDTNVAYSVSQRDDWESTDPAFREANVQGKNLIESLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLETIDLGFGKLSVAATRNSESGGSSAWIDNQRENAKYTINNVYDVRLAGLETNPGGSLELGVDYGRADTQEGYSLAPNASKDGVMLTAEHTQSLMGGFNKFVVQYATDSMTSYNTGHSQGTSVNNNGHLLRVIDHGAINLAEKWDMMYVALYQDIDLDNNNGNTWYSVGVRPMYKWTPIMSTLLEAGYDNVKSQHTGERNGQYKLTLAQQWQAGDSIWSRPAIRVFATYANWDEKWGYSDTTGVAQDGTIGTNSRGKNNEVTFGAQFEAWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin 1, Maltose-inducible porin 1.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: JBP2_LEIMA
Sequence: MLNGLTRVSTSSELESILDIVQSSGEIAVVFTSPSIGDLETIASETQRRQLRIAGIPRGGYTILPAIPLYDDELLQMCERYTAANEYEKAEMRNSLYMREYPLFAYSMRHQRALFHPADYVSRILQFCSYYVQAPDADVLSLQDRSPFLHISPIKEICTQLRLIARGTPVAASDSESPVPEQLRLHAESDVEKLAAERATAMSIAASSGGASETEQLSLFSGVAPSALFQKDAVEEVNKDAEDTMEDLTGEETVDAVHSFQAEYLTLDGFELVTKASIFYDREGEGQCIVAVYIPGGVPEDTCRAAAAVLEPAATKKNLRAPTNGGLPPDTGIVGYYDYLTNPTQHKCRETEFSRRNWGLLAQSEPLLKHLDKLYSQLAPMHHHLQRVAIPSQYQLCGTVFSTITVNRNFRTAVHTDRGDFRSGLGVLSVINGEFEGCHLAIKRLKKAFQLKVGDVLLFDTSLEHGNTEVVNPEIHWQRTSVVCYLRTGLMSSVCEMERRKHLNRLILEQLLNTEVRNTTVNINGADSSLPPLFVPTRLASHLAPVQLAALGFIVERTEKQSGCVVAMTMGLGKTLVALTLCFSQLYLAPQADILILTPKPIISHWVDEKNKWGMHGLHFPHFVASDGLNSLEFEQQLLEYERQKNNEKPKSGHIFVINGEYLAGFLRRFKRFTPLVMIVDEGHRVAAKGNKLTESLDRLRCNLRIVLSGTPLQNDASELYRLVGWVNKGVSRVLPPKRFQELANDINQFVEGDDGAFYNAVVAQEYIQDWMRGFVFREMENDLPPLHDYLLICGSSDVQREYEEKLGLTETAMTALKATEHRPHHLSTHPACYLAFISDSYQSMVSGWTVRALSNTSRQRVSQLEEIDTMRLEQYVQLVENEQLDAFIDLSGKMRVLVDIVLRVQARKEKLIVFSLYVGSQDLIHRTLTALRVCTFTVRGRDSQDRRRRAMQEFSENKDLIVLVLSTKIAAYGLDFTAANHVVLFDSWWNPQVDAQAIARAYRRNQRKPVTVYRLISATENKFVLRSQTRKIALFKCILHERTSRQALPDELEDCAANEKDEERRNFWAKLKMTSLAGDTRALLNVYRYQESVRESE
What is the function of this protein?
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU).  DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation.  Probably also acts as a DNA helicase.  Recognizes and binds specific regions of the genome, hydrolyzes ATP and allows the DNA base J de novo synthesis.  Involved in initial synthesis of DNA base J, JBP1 being able to act via the basal level of DNA base J and propagate further synthesis.  In contrast to JBP1, it does not specifically bind DNA base J, however it binds chromatin (By similarity).
What are the official names of this protein?
Bifunctional helicase and thymine dioxygenase JBP2, J-binding protein 2.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the TET family. JBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SMG_DICNV
Sequence: MRESVINVLFYLFDDILTEQDGQEADLNQMAHWLSEAGFAHEDVGRAMDWFCELGKIGDYQPIIQTNPAVRIFSPQEAYFIDEEGQDFLRGLCRAGVLDTQLQETVIERAIALEEPLSLETLHWVVMMVIMNTGASETVWERKWSQIWLVDDDDHSVMQ
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: YEAL_SALHS
Sequence: MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLNTFFPWIEKQGLTVGIIILTIGVMAPIASGTLPPSTLIHSFVNWKSLVAIAVGVFVSWLGGRGITLMGNQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ
What are the official names of this protein?
UPF0756 membrane protein YeaL.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.