PharMolix/UniProtQA huggingface dataset:
Protein: TAL_THEM4
Sequence: MKIFLDTAKIDEIKKGVEWGIVDGVTTNPTLVSKAGTPFKETIKQICEIVQGPVSAEVVSSDWQGMVEEARNLAKIDEHVVIKIPMTPDGLKAVKILSTEGIKTNVTLVFSANQSLLAAKAGASYVSPFVGRMDDIANDGMRMVEEIITIYSNYGFETEIIVASIRHPRHVLEAALMGADIATVPFAVLEKMFYHPMTDLGIERFLRDWEKYKAGR
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE21_ORYSI
Sequence: MAATAAAALAVTDELALPLRAVGDLAAAAGVSREEVVVITQCASLGGKLPFADASVGSVLAVIKKVENLGNQFITEISRVLKAGGMVLVQSSPSDQDPNNSIERKLLLGGFVDVQASAASSQDNEHSVNIKAKKASWSMGSSFPLKKATKGLPKIQIDDDSELIDEDSLLTEDDLKKPELPVVGDCEVGATRKACKNCTCGRAEAEEKVEKLNLTSEQINNPQSACGNCGLGDAFRCGTCPYRGLPAFKPGEKIALPGNFLAADM
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog 1, Fe-S cluster assembly protein DRE2 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: Y3956_STUS1
Sequence: MKSTAPSYLKHHFLIAMPQMADPNFAQTLIYLIEHGPEGAMGLIVNRPSGLSLADVLEQLRPDEPIPALCQSLPIFAGGPVQTDRGFVLHSAEQQFQATLMLGPLGMSTSQDVLFAIADGQGPQRHFVALGYAGWEAGQLEAELADNTWLSCPADPQILFDLPHDQRLQAAAASLGVDLRLLSTQVGHA
What are the official names of this protein?
UPF0301 protein PST_3956.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RUTB_ECOLC
Sequence: MMTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: HPB9_PELLE
Sequence: FLPLIAGLLGKLF
What is the function of this protein?
Shows hemolytic activity.
What are the official names of this protein?
Hemolytic protein B9.
What are the subcellular locations of this protein?
Secreted.
Protein: FIS_VIBC3
Sequence: MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVTELYELVLAEVEQPLLDTIMQYTRGNQTRAATMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: TIG_BORDL
Sequence: MILTSNVKLMPGSKVEAVIQISKEFVKAKYNEILKDYSSRLKVKGFRTGRVPFSIIEGKYSDNIRALAIENLIHKSLEEFFESAIYKPLSYAVPKILDEKLEINFDKDFEFTFVYESYPEFEISDISNFKVEIPEVVISDSDIEDELKLLQFENSIIVEDNGSVKVGSIVRVDFVELDDSLNEILATKRQDFVLTVGESDDYYGFGYDIIGMKKDEEKIVEKNYGSDYKFSELANTSKRLKIGVKDIKRRDIPELDDAFAKDVKDSLNTLEDLRDYVRENMLKVVQEKTNSLKLSKLLSGIAEKVNIDVPSSMFEAELKNVINEFSHQNKINITQLQNSSTGLEGVNDVFKENVLNKLKSKLVFQKMVDNDSSEVTELDLENELIKQAQNLKMAPQDVKKFYKERNLFGLLKDEIKRQKVKEKILQDLEEIKLEKVSFRDFVNYKTGE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: FBPC_BRUME
Sequence: MTAIRPGSVTFENVTKKFGNFTALPNLSLTVEPGTLVTLLGLSGCGKTTTLRLLAGLEHPTSGRILIGGKDVTNLPANERDVSMVFQSYALFPHMTSLENVAYGLESSGFKKNEARERAEEGLKLVGLGGMGHRLPAELSGGQQQRVAVARALVLEPQVLLLDEPLSNLDARLRRRVRTEIRELQQRLGFTAVYVTHDQDEALAVSDTIIVMKEGGIAQKGSPRDLYEAPASAFIADFMGEANVVPCEVISAENGEAVIRVAGLTHRVPARNAQPGPAQLAIRPNAVTLQPQAGGGFSGTVAHSAYLGDHIEYEIETEHGKLFIVDPAVEQSLPLQTDVSIQFKTRGLAIINQ
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATG5_ASPFU
Sequence: MRTSSMMENQVSLSSIQRAVWDGKLPLQITLASSESRTYDQTDPYLIACPRISYLPSLLPRLRAFFSPSLIEPNSQPHEGWFSFEGVPLKWHLPVGLLYDLYAGADPASKGTRVDETDHPTSSLNDTLPWRLTVHFSDWPDEELVRLDADGMVMHDAFINSVKEADFLRNGTAKGIMTLSKEDSAGLWQAVQDVDLLSFQRISNILLPPPNQPFRNVPIRFFLPLSPDSGSPSLKVVQSPLPPNIPATTNTSQSTNLRHSPATQVQTLGSALHSLLPNLFPSRRTPVLAKPVLHGAAVPMSAPIEELVRSCAYGDGWVYIVIRMMG
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production.  Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function.  The atg12-atg5 conjugate acts as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: PRSH_ECOLX
Sequence: MRLRFSVPLFFFGCVFVHGVFAGPFPPPGMSLPEYWGEEHVWWDGRATFHGEVVRPACTLAMEDAWQIIDMGETPVRDLQNGFSGPERKFSLRLRNCEFNSQGGNLFSDSRIRVTFDGVRGETPDKFNLSGQAKGINLQIADARGNIARAGKVMPAIPLTGNEEALDYTLRIVRNGKKLEAGNYFAVLGFRVDYE
What is the function of this protein?
Seems to anchor the pilus to the bacterial cell.  In addition the stoichiometric relationship between PrsH and PrsA determines the pilus length.
What are the official names of this protein?
PRS fimbrial minor pilin protein.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Secreted. Fimbrium.
Protein: IL6_SHEEP
Sequence: MNSLFTSAFSPLAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPSRLLLTTPEKTEALIKHIVDKISAIRKEICEKNDECENSKETLAENKLKLPKMEEKDGCFQSGFNQAICLIKTTAGLLEYQIYLDFLQNEFEGNQETVMELQSSIRTLIQILKEKIAGLITTPATHTDMLEKMQSSNEWVKNAKVIIILRSLENFLQFSLRAIRMK
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity).  'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity).  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity).  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ALF_CAMJE
Sequence: MGVLDIVKAGVISGDELNKIYDYAKAEGFAIPAVNVVGTDSINAVLEAAKKVNSPVIIQFSNGGAKFYAGKNCPNGEVLGAISGAKHVHLLAKAYGVPVILHTDHAARKLLPWIDGLIEANAQYKKTHGQALFSSHMLDLSEESLEENLSTCEVYLQKLDALGVALEIELGCTGGEEDGVDNTGIDNSKLYTQPEDVALAYERLGKISDKFSIAASFGNVHGVYKPGNVSLQPEILKNSQKFVKDKFALNSDKPINFVFHGGSGSELKDIKNAVSYGVIKMNIDTDTQWAFWDGVREYELKNRAYLQGQIGNPEGDDKPNKKYYDPRVWLRSGEESMIKRLEIAFEDLNCINKN
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: CATIN_DANRE
Sequence: MGSKKHRRSRSRSRSRERARVVRHDRSPGDRHSRNRSPVKSSRRRARSDSGGSRSSGGSAGPSRQRGRESGHSSDSDRQHRNTHGRNRDSSSDDDYHDKKKQALKKKHNDEKDSRSRRRKSRSSSGSSTNSSRERNRSKTSRSRERERRRRQSRSSSRERHRDQRRRRNSPERDRDRRRRSQSRSSSSSSSDSDHGGKSTQGGSSSKEEKKKQRDLMKALETPEEKRARRLAKKEAKERKKREKMGWSEEYMGYTNADNPFGDNNLLGTFIWQKALEKKGIGHLSEKNLKDRNKHIQEENRRELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWAEQEDNFHLHQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLSVEMHEPYTFLNGLTVTDMEDLLEDIKVYMELECGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALYMNIESKIQAGGSNLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPIIKEEPEKEQPISREAGSGEEEAGSSSQQADREEDEDRRSRRTGGEEAERSGRSSPEEEKKGEEEEGEKDEAPEAVLTEEDLIQQSQAEYDSGRYSPTLLQNSELPLDTHIIAEEEDLQRLLLARRQMQVTGDASESAEDLFVRRAKEGMGGDEAQFSVEMPLTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPCPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR
What is the function of this protein?
Plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (By similarity).  May be involved in the regulation of innate immune response (By similarity).  Plays a role during early embryonic development (PubMed:20348034).  Involved in the formation of the anteroposterior axis with important roles also in neural development (PubMed:20348034).
What are the official names of this protein?
Splicing factor Cactin, zCactin.
What is the protein family that this protein belongs to?
Belongs to the CACTIN family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBS_FAGCR
Sequence: MASSMISSATVATVSRATPAQATMVAPFTGLKSTAAFPATRKSNNDITSLASNGGRVQCMKVWPPLGLQKFETLSYLPPLSIESLAKQIEYLILKGWIPCLEFELEHPFVYRENNRSPGYYDGRYWVMWKLPMFGCTDATQVLAELQEASKTYPTSHIRIIGFDNKRQVQCISFIAYKPPAK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FGF2_BOVIN
Sequence: MAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGPKTGPGQKAILFLPMSAKS
What is the function of this protein?
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).  Also acts as an integrin ligand which is required for FGF2 signaling (By similarity).  Binds to integrin ITGAV:ITGB3 (By similarity).  Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity).  Functions as a potent mitogen in vitro (By similarity).  Can induce angiogenesis (By similarity).  Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity).
What are the official names of this protein?
Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism (By similarity). Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol (By similarity). Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity).
Protein: ENO4_XENTR
Sequence: MSYRAGDAARRARERYELKQAAAEFYRKLSVTERLEEALNSTFCLGPEDVYGHLANYFAQFSKPPTICQIRGRKVLDGTGEPTVEAEVFCTVKNMDKRICSSVISAASEHPKASKGPEQESNHSADIAIQWLNDLSPKLRGMSPDEQNKIDQLLSDFYQPKIEEEKERRQMEREASPMPLQPEPSPVTSPAPGKKKGSGKGKKAAVVEKPIPPEETPEAVVPGSPAIGALSLAVAKASSVLSKTPLYLHIRALRNEKLPTEFFMPTPMISILSCGTSSPGKLNLMKEVLIIPQTGLTVQQSLDMALMLQNQIVKQINAASKTGPAIKNVSPLGCMLIGGDRIEQPLDLICEACQHVGLELGTNLYLAINCAAHELMDYNKGKYEVLSGTFKSPDEMIDLYVDLINRQPAILALLDPLRKEDTVQWESLAKALGSKCYLFADAASKPVCKLLESGSMNSPPCSGTVIKHTNEITISQLLGVFKLIEGENRVAVLGCPYKESVGDSTADLAVGLGARFVKLGGLLRGERTTKYNRLLAIEDELTQAGALGFWTKNEFPVLCEVQNQPGPQETPETQ
What are the official names of this protein?
Enolase 4, 2-phospho-D-glycerate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
Protein: MINE_SYNPW
Sequence: MTLQDLLDRILGRQPASATTARERLQLVLAHDRSDLSPELLDQMRREIFEVVAKYVDIDLEEGDVTLETEDRVTALVANLPIRRSMASSKPGS
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: CORE5_ADEB2
Sequence: MSSRKIKEEMLEIIAPELYAPRHRRSVKAETKSRVKKEEIKSKRKWKRPQIDDLLTEDVEVVGATAPRRPYQWRGRKVKRVLRPGTVITFTPGVRSRERASKRSSDEIFADEDILEQYERGEGEFRYGKRSKAEAAVVLDTSNPTPSLHPVTPQMPIVHTSAAKRSAVPTVEVLAPKKRRFTESSDQLAVDMVTETSTVPPGTAVLLPARAVKQARRRFPVAVESKKPEHMVVEEVKVRDVKPVAPGIGVQTIDFKVPVDAPKPPVSITEQMDISSTPAKKVAYGPANKIIPVAWQHPSQMGFPKYVRPKRRRRVARRSKSTGRFVAAPRKRTPRRKIVLPAVRYHPSLDTVPRSQVAIWR
What is the function of this protein?
Associates loosely with the viral DNA to form an outer shell around the nucleoprotein-DNA complex and links it with the capsid by binding the endosome lysis protein.  Dissociates from the viral genome during entry.  Might be involved in nuclear capsid assembly of the viral particles through its association with NPM1/nucleophosmin.
What are the official names of this protein?
Core-capsid bridging protein, Core protein V.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae core-capsid bridging protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=Located inside the capsid (core). Present in 157 copies per virion. Localizes in the nucleoli during infection, then translocates from the nucleoli to the nucleoplasm as the infection progresses and is finally incorporated into the viral particles.
Protein: RL34_CLONN
Sequence: MKMTYQPKNRQRKKEHGFRKRMRTLSGRNIIKRRRQKGRKKLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ATP8_DUGDU
Sequence: MPQLDTTTWFITILSMLITLFILFQTKLLNYTYPLNALPISPNVTNHLTPWKMKWTKTYLPLSLPLQ
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: DPM2_BOVIN
Sequence: MATGTDQVVGLGLVALSLIIFTYYTAWVILLPFIDSQHVIHKYFLPRAYAIAIPLAAGHLLLLFVGIFITYVMLKNQNDTKKTQ
What is the function of this protein?
Regulates the biosynthesis of dolichol phosphate-mannose.  Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1.  Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis.  May act by regulating the GPI-GNT complex.
What are the official names of this protein?
Dolichol phosphate-mannose biosynthesis regulatory protein, Dolichol-phosphate mannose synthase subunit 2, DPM synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DPM2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL13_RUMCH
Sequence: MKTFMAKPQEVERKWYIIDAEGKPLGRLASEVASIIRGKNKPIFTPHVDTGDHVIVLNAEKVLLTGKKLDQKLHRYHTLHPGGLKEIKYRHLMEKHPERAIELAVKGMLPKNSLGRQMYRKLKVYRGAEHNHQAQKPEVLDLNI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: SYH_STRAW
Sequence: MSTFKAPKGTYDLIPPDSAKYLAVREAIAAPLRNSGYGYIETPGFENVELFARGVGESTDIVTKEMYAFETKGGDRLALRPEGTASVLRAALEANLHKAGNLPVKLWYSGSYYRYERPQKGRYRHFSQVGAEAIGAEDPALDAELIILADQSYRSLGLRNFRILLNSLGDKECRPVYRAALQDFLRGLDLDEDTLRRAEINPLRVLDDKREDVQKQLGGAPLLRDYLCDACKAYHEEVRELITAAGVSFEDDAKLVRGLDYYTRTTFEFVHDGLGSQSAVGGGGRYDGLSEMIGGPALPSVGWALGVDRTVLALEAEGVELELPSSTSVFAVPLGEEARRILFAKVTELRKVGIAADFAYGGKGLKGAMKNANRSGARYTVVAGERDLAEGVVQLKDMESGEQTAVGVNEIVAELEARLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTX11_ARATH
Sequence: MEDAESTTKDPVDRVEKVTWRDLQDGSFTAELKKLICFAAPMAAVVITQSMLQIITMVIVGHLGRLSLASASFAISFCNVTGFSFIMGLSCALDTLSGQAYGAKLYRKLGVQAYTAMFCLTLVCLPLSLLWFNMGKLLVILGQDPSIAHEAGRFAAWLIPGLFAYAVLQPLTRYFKNQSLITPLLITSCVVFCLHVPLCWLLVYKSGLDHIGGALALSLSYWLYAIFLGSFMYFSSACSETRAPLTMEIFEGVREFIKYALPSAAMLCLEWWSYELIILLSGLLPNPQLETSVLSVCLQTLSMTYSIPLAIAAAASTRISNELGAGNSRAAHIVVYAAMSLAVVDALMVGTSLLAGKNLLGQVFSSDKNTIDYVAKMAPLVSISLILDSLQGVLSGVASGCGWQHIGAYINFGAFYLWGIPIAASLAFWVHLKGVGLWIGIIAGAVLQTLLLALVTGCINWENQAREARKRMAVAHESELTESELPF
What are the official names of this protein?
Protein DETOXIFICATION 11, AtDTX11, Multidrug and toxic compound extrusion protein 11, MATE protein 11.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ENPP7_HUMAN
Sequence: MRGPAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALPPDGRPTLLPKGRSALPPSSRPLLVMGLLGTVILLSEVA
What is the function of this protein?
Choline-specific phosphodiesterase that hydrolyzes sphingomyelin releasing the ceramide and phosphocholine and therefore is involved in sphingomyelin digestion, ceramide formation, and fatty acid (FA) absorption in the gastrointestinal tract (PubMed:12885774, PubMed:12671034, PubMed:15205117, PubMed:16255717, PubMed:28292932).  Has also phospholipase C activity and can also cleave phosphocholine from palmitoyl lyso-phosphatidylcholine and platelet-activating factor (PAF) leading to its inactivation (PubMed:16255717, PubMed:12885774).  Does not have nucleotide pyrophosphatase activity (PubMed:12885774).  May promote cholesterol absorption by affecting the levels of sphingomyelin derived from either diet or endogenous sources, in the intestinal lumen (By similarity).
What are the official names of this protein?
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, E-NPP 7, NPP-7, Alkaline sphingomyelin phosphodiesterase, Intestinal alkaline sphingomyelinase, Alk-SMase.
What is the protein family that this protein belongs to?
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=The catalytic domain is released into the extracellular medium when cells are treated with trypsin (PubMed:15205117). Localized at the surface of the microvillar membrane in small intestine enterocytes, and in endosome-like structures situated beneath the microvillar membrane, and in Golgi complex (PubMed:12671034, PubMed:12885774).