PharMolix/UniProtQA huggingface dataset:
Protein: DEOD_ECO24
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: CC50B_MOUSE
Sequence: MTWSATARGAHQPDNTAFTQQRLPAWQPLLSAGIALPLFFCAGLAFIGLGLGLFYSSNGIKELEYDYTGNPGTGDCSVCAAKGQGRAPPPGCACSWSFTLPELFPGPVYLYYELSNFYQNNRRYGVSRDDAQLSGLASALRHPANECAPYQFRSDGLPIAPCGAIANSLFNDSFSLWHQRQPSDPFVEVPLDRTAIAWWTDYHVKFRNPPLVNGSLALAFRGTAPPPNWHRPVYELSPDPNNTGFINQDFVVWMRTAALPTFRKLYARIRQGNYSAGLPRGTYRVNITYNYPVRAFGGHKLIILSNISWMGGKNPFLGIAYLVVGSLCIVMGFVMLVVYIRYQDQDDDDNDDE
What is the function of this protein?
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids.  Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules.  The beta subunit may assist in binding of the phospholipid substrate (Probable).  Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane (By similarity).
What are the official names of this protein?
Cell cycle control protein 50B, Transmembrane protein 30B.
What is the protein family that this protein belongs to?
Belongs to the CDC50/LEM3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDH_CARMA
Sequence: MRSAVIVTMLVVVALAALLTQGQDLKYQEREMVAELAQQIYRVAQAPWAGAVGPHKRNSELINSILGLPKVMNDAGRR
What is the function of this protein?
The pigment-dispersing hormone causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas.  May also function as a neurotransmitter and/or neuromodulator.
What are the official names of this protein?
Pigment-dispersing hormone peptides.
What is the protein family that this protein belongs to?
Belongs to the arthropod PDH family.
What are the subcellular locations of this protein?
Secreted.
Protein: DDL_AZOC5
Sequence: MAKHVAVLMGGWSPEREVSLRSGAGCAKALEEVGYRVTRVDVDRDVAEVLARLKPDVALNLLHGCPGEDGTIQGILEILRIPYSHSGVLASALAMDKARAKVVMAAAGIPVPGGHLVTRAEAAKGHVLPPPYVLKPNTGGSSVGVFIVKEDQPHPPQELFRADWTFGESLMAEPFIKGLELTCGVMGDRALDVIEVEAVHGFYDYESKYAAGGSRHILPARVLPQIYQQVRMLALEAHRALGCRGISRADFRYDDTLPDGKGLVCLEVNTQPGMTETSLVPDMAAHAGISFGELVTWMVEDATLDR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_ALIB4
Sequence: MIQSFTRLNVADNTGAKEIMCIKVLGGSKRRYATVGDVIVASVKKALPTGKIKKGQVVKAVVVRTHKEVQRENGSLIRFDDNAAVILDAKREPVGTRIFGPVAREVRYSGFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: LPXK_VIBC1
Sequence: MVEKIWFDNHPLKYLLWPLLWPLSLLFGAISKSKRQQYQSGKKQAYKAPVPVVVVGNITAGGNGKTPVVVWLVEQLQQLGYKPGVVSRGYGAKAPQYPLVLDDNTPAKHCGDEPKLIYRRTAAPVAVDPVRANAVKALLETSVDIIITDDGLQHYALERDIEFVIVDGNRRFGNESLIPLGPLREGVERLSEVDFIITNGGQAQYGEMPMSLTPSKAINLKTKQQVEVSELRDLVAFAGIGHPPRFFNTLNAMNADVKVTKGFADHQDFDRQELQALAQQGANVIMTEKDAVKCDSYAQDNWWYLPVSAQFESNDAERILNRIKEVKATYGSPSA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: SYP_ECOL6
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVLMPVVQPSELWQESGRWEQYGPELLRIADRGDRPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOMPC_CHLTH
Sequence: MKKLLKSVLVFAALSSASSLQALPVGNPAEPSLMIDGILWEGFGGDPCDPCTTWCDAISMRVGYYGDFVFDRVLKTDVNKEFQMGAAPTTSDVAGLQNDPTINVARPNPAYGKHMQDAEMFTNAAYMALNIWDRFDVFCTLGATTGYLKGNSASFNLVGLFGTKTQSSSFNTAKLIPNTALNEAVVELYINTTFAWSVGARAALWECGCATLGASFQYAQSKPKVEELNVLCNASEFTINKPKGYVGAEFPLNITAGTEAATGTKDASIDYHEWQASLALSYRLNMFTPYIGVKWSRVSFDADTIRIAQPKLAEAILDVTTLNRTTAGKGSVVSAGTDNELADTMQIVSLQLNKMKSRKSCGIAVGTTIVDADKYAVTVEARLIDERAAHVNAQFRF
What is the function of this protein?
Permits diffusion of specific solutes through the outer membrane.
What are the official names of this protein?
Major outer membrane porin, serovar C, MOMP.
What is the protein family that this protein belongs to?
Belongs to the chlamydial porin (CP) (TC 1.B.2) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SYP_PARD8
Sequence: MAKELKELTPRSVNYSQWYQDLVIKADLAENSAVRGCMVIKPYGYAIWEKMQRILDDMFKETGHVNAYFPLLIPKSFLSKEAEHVEGFAKECAVVTHYRLKTNHDGTGVVVDPAAKLEEELIIRPTSETIIWNTYRNWIQSYRDLPILCNQWANVMRWEMRTRLFLRTAEFLWQEGHTAHATREEAEIEAKKMQDVYANFAENYMAMPVIKGVKSESERFAGALDTYTIEAMMQDGKALQAGTSHFLGQNFGKAFDVTFIDKNGKSDYAWATSWGVSTRLIGALIMSHSDDNGLVLPPHLAPIQVVIVPIYRSAEQLTQISEKVAGIVAKLKALGISVKYDDADNKKPGWKFAEYELKGVPVRLAMGGRDLENNTIEVMRRDTLEKETITCDGIEEYVKNLLEEIQANIFKKAYDHREANIINVDTYEEFKEKIEDGVFIMAHWDGTPETEELIKNETKATIRCIPLAGDKTPGKCMVTGKPSACRVLFARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDTA_CHLP6
Sequence: MIKGRRTKLHTFLYDCFLIFAFMVGLPRILYKRFVHGKYTKSLGIRFGFKKPEVPGTGPVAWFHGASVGETALLLPLLKRFMKEYPEWRCVVTSCTESGHENAHRLFGPLGVTTFILPLDLSIIIKPVVRAISPSLLVFSEGDCWLNFIEEAKRLGATAVIINGKLSANSCKRFTILKRFGRNYFSPVDGFLLQDEQHKARFLQLGVDKEKIQVTGNIKTYTETLSENNQRDYWREKLQLAQDTELLVLGSVHPKDVEVWLPVVRELRRNLKVLWVPRHIERSKELEALLSKENISYGLWSKEATFAQHDAIIVDAIGWLKQLYSAADLAFVGGTFDDRIGGHNLLEPLQCGVPLIFGPHIQSQSDLAERLLSMGAGCCLDKTNIVKVITFLLDHPEERAAYIQKGAMFLHEEKVAFDRTWESFKRYIPCVKI
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Catalyzes the transfer of predominantly four 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.  Thus generates the genus-specific LPS epitope of Chlamydia, composed of the trisaccharide alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid transferase, Kdo transferase, Kdo(2)-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase, Kdo(3)-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase, Kdo-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase, Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase, Multifunctional Kdo transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: SDHF2_CRYNJ
Sequence: MSVLRALPRVARVVRPAPPSLRSISTTNTIFKSPTADPFPLPFSDPELAHANNSLPSNSEEWPLPEPLDRTGEDEKTLRARLIYQTRKRGTLETDLILSTFARDELPNMDFEEMKQFDKLLDEPDWDIFYWSVKKRDPPARWKGTPLLEKLQKHAKNEGKVVRMMPELMQKEPDL
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: AP3S1_BOVIN
Sequence: MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated.  The complex is associated with the Golgi region as well as more peripheral structures.  It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity).
What are the official names of this protein?
AP-3 complex subunit sigma-1, AP-3 complex subunit sigma-3A, Adaptor-related protein complex 3 subunit sigma-1, Sigma 3A-adaptin, Sigma-adaptin 3a.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: MIA40_CANAL
Sequence: MYRTISRSSSGLIRQSTARLTRQLSTTRTTPSQYNSKLLLGVLGTGALAFGYFSQQSSLIQNASTAENIEKVFEEGNAVAKDAQESLDARQEKVIKENEQKTKKAEDAKTSSESKANVADKKSNSQPEGEPEGEGKQEAAFNPDTGEINWDCPCLGGMAHGPCGEEFKEAFSCFVFSETEPKGIDCIKKFENMRSCFKRYPEHYKDELYDDGEEEASTEVVEHVVLETSEPAIEQIEQGIKEDKVKPNTKSD
What is the function of this protein?
Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS).  Forms a redox cycle with ERV1 that involves a disulfide relay system.  Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria.  The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS (By similarity).
What are the official names of this protein?
Mitochondrial intermembrane space import and assembly protein 40, Mitochondrial import inner membrane translocase TIM40.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass type II membrane protein; Intermembrane side.
Protein: TYSY_STRP1
Sequence: MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFAEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYDNQFDQAQELLKRQPVASQPKLVLNVPDRTNFFDIKPDDFELQNYDPVKPQLHFDLAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_STAA1
Sequence: MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_ECO81
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTALGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHILKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGEKPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCM6_ORYSI
Sequence: MEAFGGFFVDEKAARVENIFLEFLRRFKEADAAEAFYETELEAMRSRESTTMYVDFAHVMRFNDVLQKAISEEYLRFEPYLRNACKRFVMEQRTGENRAPIISDDSPNKDINIAFYNIPMLKRLRELGTAEIGKLTAVMGVVTRTSEVRPELLQGTFKCLDCGNVVKNVEQQFKYTEPIICVNATCQNRSKWALLRQESKFTDWQRVRMQETSKEIPAGSLPRSLDVILRHEIVEKARAGDTVIFTGTVAAVPDVMALTSPGERAECRREAPQRKNGSGVQEGVKGLKSLGVRDLSYRLAFVANSVQVADGRREVDIRDRDIDGDDSERQKFTEEEEDEVVRMRNVPDFFNKIVDSICPTVFGHQEIKRAILLMLLGGVHKITHEGINLRGDINVCIVGDPSCAKSQFLKYTAGIVPRSVYTSGKSSSAAGLTATVAKEPETGEFCIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPTGGRYDKSKPLKYNVALPPAILSRFDLVYIMIDEPDENTDYHIAHHIVRVHQKREEALAPAFSTAELKRYIAFAKSLKPQLSSEAKKVLVESYVTLRRGDSTPGTRVAYRMTVRQLEALIRLSEAIARSHLERVVLPAHVRMAVKLLKTSIISVESSEVDLSDFQDADDGTNVPADNDAGQPTEMDAAPQQDGPENEQAADTGKKKLVITEEHFQRVTQALVMRLRQHEESVTKDGDGLAGMKQGDLIIWYVEQQNAQGAYSSTAEVKEEVKCIKAIIERLIQRDGHLIVIDEGAAPAADDGAARRTSESRILAVNPNYVID
What is the function of this protein?
Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.
What are the official names of this protein?
DNA replication licensing factor MCM6, Minichromosome maintenance protein 6.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURG_VIBC1
Sequence: MKKNKRLMVMAGGTGGHVFPGLAVAKQLQEQGWEIRWLGTADRMEADLVPKHGIEIDFIKVKGLRGQGVKRLLAAPFQIINAIMQARAHMKRWQPDAVLGMGGYVSGPGGIAAWMSGIPVVLHEQNAVAGLTNQWLSKIAKKVFQAFPGAFPNAEVVGNPVREDVTQLAAPTERMQERQGPIRILVMGGSQGARILNQTLPEVMAKLGDDYSIRHQAGKGSAEEVNAAYQANGVANADVTEFIHDVAEAYAWADLLVCRSGALTVSEVSAAGVGAIFVPFMHKDRQQALNADHLVDCGAAKMIEQPDLTVESLTQQIQQLDRQALLTMAEQARGAAKLNADRVVAQAIVALTEKR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HGPRT_STRPQ
Sequence: MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKGSVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDIIDTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDYAENYRNLPYVGVLKEEVYSK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA1_PARXL
Sequence: MNAVTDTPVTEMPAPFVFTDAAADKVKQLIEEEGNADLKLRVFVQGGGCSGFQYGFTFDEAVNEDDTVMNKSGVQLLIDSMSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA 1.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: SSU1_CANAL
Sequence: MSSSSHNDNKIPPEKTTTPPLSSSNEDIYNPADSSNVLSSNQTLVSTNNNNNNNQNNNQNNNQNNDGKDTMDHLSYLSTIDSKRREQSYLKSFYQRFIIEDVVKNFTPAYFVSVMGTGISSSLLYNFPFPAYWLQICGYVMFGLTCTFFIGNIILLIMSCAYYPNRFRDYHVDPSRAVFMGAFSMGYITIVNFIALITKGEHIYFVWTLWWLAVFSAMYTSFLIVYLSFMSKLNESDVEAKLNATLLLPIVAITVVSSSGHSIELDLPHVHQTVLTMIVSFMLWSLSISMAFMVMTLYMGRLIIHKIPPTNLIMTSFLPVGFLGQSSYSIYLFGNNLNKFIPEELLYGKISLCLSGFVSVFLLSFGYFMCFVAVTSVLSKIRPFAKNPNPSHTNRFGLLKLEKSFWSMTFPMGTMSLSNTEIGHGGVGNYPLLTFKVMGSIFAAACIFITVGCSIGVVVYSFKKLREDMTNKNKYRNESMV
What is the function of this protein?
Sulfite efflux pump required for the secretion of sulfite as a reducing agent (By similarity).  Plays a role in resistance to neutrophils during infection.  Involved in transition to filamentous growth, which is believed to be central to the virulence of this human pathogen.
What are the official names of this protein?
Sulfite efflux pump SSU1, Sulfite sensitivity protein SSU1.
What is the protein family that this protein belongs to?
Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS10_SINFN
Sequence: MNGQNIRIRLKAFDHRILDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRSPHVDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RHG15_MOUSE
Sequence: MEKRTSCSVQTSTNCDNSLEILNSAHQATGAVQMRIKNANSHQDRQSQTKSMILTDAGKVTEPISRHRRNHSQHVLKDVIPPLEHPMVEKEGYLQKAKIADGGKKLRKNWSTSWIVLSGRKIEFYKDSKQQALPNMKTRHNVESVDLCGAHIEWAKEKSSRKSVFQITTVSGNEFLLQSDIDFLILDWFQAIKNAIDRLPKNPSCGSLELFNLQRSSSSELPSHCHIDRKEQKPEHRKSFMFRLHHSASDTSDKNRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHTVCEREHSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSNEKIETMRSLVKRLPPPNHDTMKILFRHLTKIVAKASQNLMSTQSLGIVFGPTLLRAENESGNVAVHMVYQNQIAEFMLTEYDKIFSSEED
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.  Has activity toward RAC1.  Overexpression results in an increase in actin stress fibers and cell contraction (By similarity).
What are the official names of this protein?
Rho GTPase-activating protein 15, ArhGAP15, Rho-type GTPase-activating protein 15.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: KCJ13_CAVPO
Sequence: MESSNCKVITPLLSQRHRRMVTKDGHSTLQTDGAPRGLVYLRDAWGTLIDMRWRWVMLVFSASFVLHWLVFAVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDLAVVAHRDGKPNLIFQVANIRHSPLTSVRVSAVLYQERENGQLHQTSVDFHLDGISSEECPFFIFPLTYYHSITPSSPLVTLLQHENPPHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEYKVKMENFDKTVPELPTPLVSKSPHRTDLDIRINGQSIDNFQISETGLTE
What is the function of this protein?
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium (By similarity).
What are the official names of this protein?
Inward rectifier potassium channel 13, Inward rectifier K(+) channel Kir7.1, Potassium channel, inwardly rectifying subfamily J member 13.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ13 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MSCL_SHEB8
Sequence: MSLIKEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADIIMPPIGIILGGVNFSDLSIVLQAAQGDAPSVVIAYGKFIQTIIDFTIIAFAIFMGVKAINRLKRKEEVAPKAPAAPTKDQELLSEIRDLLKAQQEK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.