PharMolix/UniProtQA huggingface dataset:
Protein: OPGD_ECOLI
Sequence: MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQRFDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLDAQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAGFRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFWFDTVKPGATTFTVYALLDSASITGAYKFTIHCEKSQVIMDVENHLYARKDIKQLGIAPMTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNPKGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVCFWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFSEGWAPGEHYPEKWARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSDSTDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: C80B2_COPJA
Sequence: MEVLSIAIVSFSFLLFLFFILRDSRPKNLPPGPRPSPIVGNLLQLGDKPHAEFAKLAQKYGELFSLKLGSQTVVVASSPAAAAEILKTHDKILSGRYVFQSFRVKEHVENSIVWSECNDNWKLLRKVCRTELFTPKMIESQSEIREAKAREMVKFLRGKEGEVVKIVEVVFGTLVNIFGNLIFSKDVFDLEDPTGGSVELKEHLWKLLDMGNSTNPADYFPIMGKLDLFGQRRAVAEVLQQIYDVWGVMLKERRGTKGSESKNDFVDVLLNAGLDDQKINALLMELFGAGTETSASTIEWAITELTKKPLVVSKIRLELVNVVGDNTVKESDLPHLPYLQAFVKETLRLHPPTPLLLPRRALETCTVMNYTIPKECQIMVNAWAIGRDPKTWDDPLNFKPERFLSSDVDYKGNDFELIPFGGGRRICPGLPLASQFSNLIVATLVQNFEWSLPQGMSTSELSMDEKFGLTLQKDPPLLIVLKARASNI
What is the function of this protein?
3'-hydroxylation of (S)-N-methylcoclaurine.
What are the official names of this protein?
Probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2, Cytochrome P450 80B2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: BSHC_CHLP8
Sequence: MNTFLIDYQRIQTPKKGFSRLFCDYTSDTEARAKLVSNCFHLDYRKDADYYRHLGLLASRDFKRNALVELLLKQNSRFGGSERQRQEIEKLRSSRCMAIVTGQQTGLFTGPMYTIYKALSAVVIARKQKELFPEYDFVPVFWIESEDHDFDEASATALFAGAGLETIQAEGGHRQQDQMAGPTPLGSGITETVREFLDLLPDSDFKPEIAELLHSAYTPESTFEIAFATTMNRLFSNHPLILLSTQDAEFKRLAAPMLCKEIESAPASSYDVVAQSSTLESMGYPAQTKPRAVNLFYLNQLGQRLKIEQPSPENFMILPDRQRYTRHQLLEFCQDHPERFSPNVILRPIVQDAVLPTFAYIGGPGEVSYLSQFRKVYERFGLVMPFVIPRGSFTLVEPKITRTMDKVLKVTGKPSFSRRQVYEALFGNLQELRKSMVSGAENQNLDALFEQVESEVTRSLSTLEPALVKMDPTLQQALAGSSGQIAKIIGNIREKTYRAGRRKHDELLQQLDKAELNLFPEGVPQERLINIFYYLNKYGPSLIDDLERVLQGYSTESHLIVEL
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: NDHO_PARMW
Sequence: MAETDSKAPAKAKPAALRKGALVKVNRSAYNDSLEAAASDPTAPDYIFEGPGELLLVKGDYGQVRWNRPVPDVWLRMDQLESCG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit O, NAD(P)H dehydrogenase I subunit O, NDH-1 subunit O, NDH-O.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhO subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: F264_MOUSE
Sequence: MASPRELTQNPLKKIWMPYSNGRPALHASQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRRDIVKTYKSFEFFLPDNEEGLKIRKQCALAALSDVRKFLSEEGGHVAVFDATNTTRERRAMIFNFGEQNGYKTFFVESICVDPEVVAANIVQVKLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFSKHLAQFISDQNIKDLKVWTSQMKRTIQTAEALSVPYEQWKVLNEIDAGVCEEMTYEEIQDHYPLEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEELPYLKCPLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPSEEALVTVPAHQ
What is the function of this protein?
Synthesis and degradation of fructose 2,6-bisphosphate.
What are the official names of this protein?
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4, 6PF-2-K/Fru-2,6-P2ase 4, PFK/FBPase 4, 6PF-2-K/Fru-2,6-P2ase testis-type isozyme.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphoglycerate mutase family.
Protein: YP2C_STAAU
Sequence: MNNEKNKQDRENLNRQDERKSSEIKSERKSGLDLIEVRKQLDRIESVANEKNENESEKLENLKNRIEELEKSEQDRNERTNILMKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDNLKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKVMTKGVTNIFFVLIIFVLVMLVTGPIVISLVLNIYIALLMVLLMTTKVHGDI
What are the official names of this protein?
Uncharacterized 27.7 kDa protein.
Protein: RS7_MYCSK
Sequence: MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLDGKKSLAERIVYGALEQARDKTGTDPVVTLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSVTLALRWLVSFSKARREKTMVERLANEILDASNGLGAAVKRREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RS14Z_MYCTO
Sequence: MAKKALVNKAAGKPRFAVRAYTRCSKCGRPRAVYRKFGLCRICLREMAHAGELPGVQKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: SUCA3_TRIVA
Sequence: MLSSSFERNLHQPLLFIDKDTKVVIQGIGNQGQFHSRLMRQYGTKVVGAVHPKKAGSIIAGLPIFKNMKEVVKRTDANASLIFVPAPGAAAACIEAAQAGMGLVVCITEHIPQHDMIKVKKVMKETGCQLIGPNCPGLIQPGTHTKLGIIPTNIFNNGKIGIVSRSGTLTYEAAYATTLAGLGQSTVVGIGGDPFAGQLHTDVVKRFAADPQTEGIILIGEIGGTSEEDAAEWIAKTKLTQEKPVVAFIAGATAPPGKRMGHAGAIVSGGKGTAEGKYKALEAAGVRIARHPGNMGKFIFEEMKRMGKI
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha-3, mitochondrial, Succinyl-CoA synthetase subunit alpha-3, SCS-alpha-3.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Hydrogenosome lumen.
Protein: TAT_SIVCZ
Sequence: MDPIDPDLEPWKHPGSQPRTVCNNCYCKACCYHCIYCFTKKGLGISYGRKKRTTRRRTAPAGSKNNQDSIPKQPLSQSRGNKEGSEKSTKEVASKTEADQ
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: BIOC_BUCBP
Sequence: MIDKKKIAEAFGKAAANYDNFSVIQRIAGNILLSKIETFFNISILDAGCGTGWFSKKWRQLGNTVTALDFSKNMLLTAKNTNSADYYLHADMEQLPICDNIFDLSWSNLSLQWCNKFNKAISELCRVTKPGGMVVFSTIAHGSLYEFNKAYRTINSSYQENKFLSINDIKLSCCNKKTLIDNILITFSFSKILEAMYSFKKIGANYISSNHSKILTKKKIRQLQENWPYNPNGYLLSYRFVFGVIYL
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: SSRP_PSEA7
Sequence: MAKQKKHPSGTIAQNKKALHDYFIEQRFEAGVALAGWEVKSLRAGKAQLVDSYVLLKDGEAWLLGSHITPLTTASTHVIADPVRTRKLLLHKRELGKLFGAVQQKGYACVALSMYWKKHLVKCEIALAKGKKDFDKRHTEKERDSDREIQRAMRHGKDD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: NKX62_HUMAN
Sequence: MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAVEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAGDAL
What is the function of this protein?
Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes.  Binds to the consensus DNA sequence 5'-(A/T)TTAATGA-3'.  In oligodendrocytes, binds to MBP and PLP1 promoter regions.
What are the official names of this protein?
Homeobox protein Nkx-6.2, Homeobox protein NK-6 homolog B.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSNC_ASPOR
Sequence: MPIKSFASRLALSLAICGTAMGQKVNGADYNKPDGGPPAKFFQASSSIPVAAIQAAAAKASKVPSHATYPIGQGSTKSTIHSDWAGFSEGAAFSFIADMDVDCDGLNHGCKGNPDGQKETNWGALSAYEVPFIVIPQEFLDANKGTLKGNAVAAVICATSSNGKMFYGIFGDSNGDSPQVTGEASWLMARTCFPEEDLNGNKGHTAADVTYIVFTGDKAVLPSSALNKNYITNFDTLRSMGDSLVGALAKNLNLGGGGGNPPTTLTTTSIPEPTGGSGSCSWPGHCAGFKNKGATCSSNDDCSDDLACQNGKCASDGSAETCSWEGHCKGATCSSNDDCSDELACISGICSVDNGVETCEWEGHCEGASCSSHDDCDGNLACKNGKCSA
What is the function of this protein?
Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin.  Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.  Chitoolisaccharides produced by the hydrolysis of partially N-acetylated chitosan are known to have many biological activities, including antibacterial activity, immune-enhancing effects, and elicitor activity (By similarity).
What are the official names of this protein?
Endo-chitosanase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 75 family.
What are the subcellular locations of this protein?
Secreted.
Protein: END4_SHIFL
Sequence: MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQNDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: LYS_BPCP7
Sequence: MVKKNDLFVDVASHQGYDISGILEEAGTTNTIIKVSESTSYLNPCLSAQVSQSNPIGFYHFAWFGGNEEEAEAEARYFLDNVPTQVKYLVLDYEDHASASVQRNTTACLRFMQIIAEAGYTPIYYSYKPFTLDNVDYQQILAQFPNSLWIAGYGLNDGTANFEYFPSMDGIRWWQYSSNPFDKNIVLLDDEKEDNINNENTLKSLTTVANEVIQGLWGNGQERYDSLANAGYDPQAVQDKVNEILNAREIADLTTVANEVIQGLWGNGQERYDSLANAGYDPQAVQDKVNEILNAREIADLTTVANEVIQGLWGNGQERYDSLANAGYDPQAVQDKVNELLS
What is the function of this protein?
Responsible for the separation of the host daughter cells at the end of cell division and participates in the liberation of progeny bacteriophage into the medium.  Degrades cell walls containing either choline or ethanolamine.
What are the official names of this protein?
Lysozyme, CP-7 lysin, Endolysin, Muramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 25 family.
Protein: ZDS_SYNY3
Sequence: MRVAIVGAGLAGMATAVELVDAGHEVELYEARSFIGGKVGSWVDGDGNHIEMGLHVFFGCYYNLFNLMEKVGAKQNLRLKEHTHTFVNQGGRIGELDFRFLTGAPFNGLKAFFTTSQLDTKDKIANSIALATSPIVRGLVDFDGAMKTIRDLDRISFAEWFLSKGGNEGSLKKMWDPIAYALGFIDTENISARCMLTIFQLFAARTEASVLRMLEGSPQEYLHKPIQEYLEQRGTKFYTRHKVKEIKTKVTDGETRVTGLIINDGVETKTVTADAYVAACDVPGIKNLLPENWRTQWDFFNKIYYLDTVPVATVQLRFDGWVTEMNDPAKRKQLEQAFGLDNLLYTSDAEFSCFADLALTSPADYYRPGEGSLLQLVLTPGDPFMKESNEAIAYRVLKQVKALFPSAADLNMTWYSVIKLAQSLYREAPGMDLFRPSQATPIANFFLAGSYTQQDYIDSMEGATLSGRQAAQAILANQARLQTAVLASQ
What is the function of this protein?
Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene.  It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' (By similarity).
What are the official names of this protein?
Zeta-carotene desaturase, 9,9'-di-cis-zeta-carotene desaturase, Carotene 7,8-desaturase.
What is the protein family that this protein belongs to?
Belongs to the zeta carotene desaturase family.
Protein: KHSE_AZOC5
Sequence: MAVYTDVSAASLSDYLAAYDIGTLVSYHGIAEGVENSNFLVQTTTASFILTLYEKRVDPADLPFFIGLMQHLAANGISCPQPVAMRDGTMLGTLAGRPCAIVTFLPGVSVRKPTAANCGQLGRALAQLHLAGAGFEITRRNALSVSGWRPLFEAAGPRTDTVHPGLAAIITEELAAHEAHWPAALPAGVIHADLFPDNAFFLDDTLSGIIDFYFACNDLFAYDVAVCLNAWCFEADGAFNATKGRALLAGYQAVRPMEAAEVEALPQLARGAALRFLLTRLVDWLNVPEGALVRPKDPLEYLRKLRFHRAVASARDYGLAA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: Y005_CORGB
Sequence: MTDPIEQAFERIRAEAMRRNGSVPDLNKNDAFRRPPAPKGGVEKRKKGRASGLDGRQKRYVRGAESLGSVLNKEIQRRGWGKDIAGGWVTSNWEELVGAKIAQHTRVEMIKDKKLFITCDSTAWATNLRMMQRQILQVIAEKVGPNIITELRIFGPQAPSWRKGPLHVKGRGPRDTYG
What are the official names of this protein?
UPF0232 protein cgR_0005.
What is the protein family that this protein belongs to?
Belongs to the UPF0232 family.
Protein: BOLA3_MOUSE
Sequence: MAAWGPAAAAPLLRGSRGLPLWHCAQRMFASQTEGELKVTQVLKEKFPRATAIQVTDISGGCGAMYEIKIESEEFKEKRTVQQHQMVNQALKEEIKGMHGLRIFTSVPKC
What is the function of this protein?
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins.  Probably acts together with NFU1.
What are the official names of this protein?
BolA-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYP_ROSS1
Sequence: MPKEGITPRAQDYSQWYLDIVQQADLADYAEVVKGCIVFKPTGYAIWEAIQRGLDDRIKATGHVNAYFPLLIPKSFLMKEAEHVEGFAPEVAEVTRAGGEDLAEPYVIRPTSETIIGYFYSKWVRSYRDLPLLINQWANVMRWEMRTRPFLRTTEFLWQEGHTVHATEEDAERETLLILHEVYADFVEKEMAIPVIKGLKSEKEKFPGALRSYCIEAMMQDGRALQAGTSHNLGQNFARAFDITYTDQQNTIQYAWTTSWGVSTRLIGALIMTHSDDEGLVIPPRLAPTQVVVVPIYRNDAERSVVMEAVQRMTAEWKGRLRFKIDDRDNLTPGFKFNEWELKGVPIRVEIGPKDIEKGSVAIARRDQPGREGKSFVPQDGLTDRLTALLEEIQQALYRRALTFREDHTADVATYDELKQQVERGFARCYWAGTTEDEKRIQEETRATIRCIPLDQPQQAGRCVYTGKETTQQVIFARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSK_PSEAE
Sequence: MRRKNSDLKDSTTASHAAAWRQQLHSRLKEGVLIALGALCLYLWMALLTYDSADPSWSHSSQVDQVQNAAGRLGAVSADILFMTLGYFAYLFPLLLGIKTWQVFRRRNLPWEWNTWLFSWRLVGLIFLILAGSALAYIHFHASGHMPASASAGGAIGQSLGRVAVDALNVQGSTLVFFALFLFGLTVFADLSWFKVMDVTGKITLDFFELIQNAFNRWMGARAERKQLVAQLREVDERVAEVVAPSVPDRREQSKAKERLLEREEALAKHMSEREKRPPPKIDPPPSPKAPEPSKRVLKEKQAPLFVDTAVEGTLPPLSLLDPAEVKQKSYSPESLEAMSRLLEIKLKEFGVEVSVDSVHPGPVITRFEIQPAAGVKVSRISNLAKDLARSLAVISVRVVEVIPGKTTVGIEIPNEDRQMVRFSEVLSSPEYDEHKSTVPLALGHDIGGRPIITDLAKMPHLLVAGTTGSGKSVGVNAMLLSILFKSTPSEARLIMIDPKMLELSIYEGIPHLLCPVVTDMKEAANALRWSVAEMERRYRLMAAMGVRNLAGFNRKVKDAEEAGTPLTDPLFRRESPDDEPPQLSTLPTIVVVVDEFADMMMIVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQGGAEQLLGHGDMLYLPPGTGLPIRVHGAFVSDDEVHRVVEAWKLRGAPDYIEDILAGVDEGGGGGGSFDGGDGSGEGSEDDPLYDEAVRFVTESRRASISAVQRKLKIGYNRAARMIEAMEMAGVVTPMNTNGSREVIAPAPVRD
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (Probable).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: RL4_STAAR
Sequence: MANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASLRQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMPKKMRRLALRSALSFKVQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENEDVNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKKVEEVLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PLBL2_HUMAN
Sequence: MVGQMYCYPGSHLARALTRALALALVLALLVGPFLSGLAGAIPAPGGRWARDGQVPPASRSRSVLLDVSAGQLLMVDGRHPDAVAWANLTNAIRETGWAFLELGTSGQYNDSLQAYAAGVVEAAVSEELIYMHWMNTVVNYCGPFEYEVGYCERLKSFLEANLEWMQEEMESNPDSPYWHQVRLTLLQLKGLEDSYEGRVSFPAGKFTIKPLGFLLLQLSGDLEDLELALNKTKIKPSLGSGSCSALIKLLPGQSDLLVAHNTWNNYQHMLRVIKKYWLQFREGPWGDYPLVPGNKLVFSSYPGTIFSCDDFYILGSGLVTLETTIGNKNPALWKYVRPRGCVLEWVRNIVANRLASDGATWADIFKRFNSGTYNNQWMIVDYKAFIPGGPSPGSRVLTILEQIPGMVVVADKTSELYQKTYWASYNIPSFETVFNASGLQALVAQYGDWFSYDGSPRAQIFRRNQSLVQDMDSMVRLMRYNDFLHDPLSLCKACNPQPNGENAISARSDLNPANGSYPFQALRQRSHGGIDVKVTSMSLARILSLLAASGPTWDQVPPFQWSTSPFSGLLHMGQPDLWKFAPVKVSWD
What is the function of this protein?
Putative phospholipase.
What are the official names of this protein?
Putative phospholipase B-like 2, 76 kDa protein, p76, LAMA-like protein 2, Lamina ancestor homolog 2, Phospholipase B domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase B-like family.
What are the subcellular locations of this protein?
Lysosome lumen.
Protein: TM39B_HUMAN
Sequence: MGGRRGPNRTSYCRNPLCEPGSSGGSSGSHTSSASVTSVRSRTRSSSGTGLSSPPLATQTVVPLQHCKIPELPVQASILFELQLFFCQLIALFVHYINIYKTVWWYPPSHPPSHTSLNFHLIDFNLLMVTTIVLGRRFIGSIVKEASQRGKVSLFRSILLFLTRFTVLTATGWSLCRSLIHLFRTYSFLNLLFLCYPFGMYIPFLQLNCDLRKTSLFNHMASMGPREAVSGLAKSRDYLLTLRETWKQHTRQLYGPDAMPTHACCLSPSLIRSEVEFLKMDFNWRMKEVLVSSMLSAYYVAFVPVWFVKNTHYYDKRWSCELFLLVSISTSVILMQHLLPASYCDLLHKAAAHLGCWQKVDPALCSNVLQHPWTEECMWPQGVLVKHSKNVYKAVGHYNVAIPSDVSHFRFHFFFSKPLRILNILLLLEGAVIVYQLYSLMSSEKWHQTISLALILFSNYYAFFKLLRDRLVLGKAYSYSASPQRDLDHRFS
What is the function of this protein?
May protect the cells against DNA damage caused by exposure to the cold-warming stress and facilitates tissue damage repair during the recovery phase.
What are the official names of this protein?
Transmembrane protein 39B.
What is the protein family that this protein belongs to?
Belongs to the TMEM39 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISC3_BOMMO
Sequence: DEPTTDLPICEQAFGDAGLCFGYMKLYSYNQETKNCEEFIYGGCQGNDNRFSTLAECEQKCIN
What is the function of this protein?
Inhibits chymotrypsin and thus avoids the accidental chymotrypsin-mediated activation of prophenoloxidase.  This enzyme is required by the insect immune system to produce melanin which is used to engulf foreign objects.
What are the official names of this protein?
Chymotrypsin inhibitor SCI-III.
Protein: CMR1_CHAGB
Sequence: MPPKKEPVISAFERKRLENIANNNAILSGISTTAEKIIPKPAPPKPKRASAPRAKREPVKRETARPTRQSSRLAGLDADADTLKRKAEVEAEVEAEKAKAKKMRVSGDLSLGDIQVEGRKWENGLDGLAGLKGLSARGAQPGIRTFTDEDVKGTTDKGLKDLRLRMSGLKLYEKWPVQGAYPKLVPQRVYSLGFHPTESKPIIFAGDKEGAMGVFDASQEPVKAEDDDDDEEAEIPDPIISAFKTHSRTITSFHFSPVDANAVYSASYDSSIRKLDLDKGVSTEAFAPADADEDLPISAIDMPTSDPNMIIFSTLQGTLGRHDLRTKSSTAEIWGLTDQKIGGFSLHPAQPHLVATASLDRTLKIWDLRKIQGKGDARAPALLGTHDSRLSVSHASWSSAGHVATSSYDDRIKIYNFPDADKWTAGAALTEAQMEPARQIPHNNQTGRWVTILKPQWQRSPRDGLQKFVIGNMNRFVDVFAADGEQLAQLGGDGITAVPAVAHFHPTMDWVAGGNGSGKLCLWM
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein CMR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.