PharMolix/UniProtQA huggingface dataset:
Protein: KDC_MYCPA
Sequence: MPVTDAATEPAYTVGDYLLDRLAELGVSEIFGVPGDYNLEFLDHIVAHPRLRWVGNANELNAGYAADGYGRLRGMSALVTTFGVGELSAANAVAGSYAEQVPVVHIVGGPSKDAQGTRRALHHSLGDGDFEHFFRVSREITCAQANLMPATARREIDRVLSEVREQKRPGYILLSTDVARFPTEPPEAALPRYTGGTSPRALAMFTEAAAALIGEHRITVLADLLVHRLQAIKELEALLAADVVPHATLMWGKSLLDESSPNFLGIYAGSASAPAVRTAIEEAPVLVTAGVVFTDMVSGFFSQRIDPARTIDVGQYQSSVAGEVFAPLEMGEALQALTAILTRRGVSSPPVASPPAEPLPPPPPREQPLTQKMVWDRVCTALTPGNVVLADQGTSFYGMADHRLPQGVTFIGQPLWGSIGYTLPAALGAAVAHPDRRTVLLIGDGAAQLTVQELGTFAREGLSPVIVVVNNDGYTVERAIHGETAPYNDIVGWKWTEVPNALGVTEHLAFRVQTYGELDDALTAAARHQDRMVLVEVVLPRLEIPRLLVELVRPTSPDGSPRR
What is the function of this protein?
Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.
What are the official names of this protein?
Alpha-keto-acid decarboxylase, KDC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: PDXA_RHOPA
Sequence: MTGMAKPLALTLGEPAGIGPDIALAAWLKREQHGLPPFYLLGDAGCLSRCAKLLGLDVPLAEVKAEDAAAAFATTLPVVSTGQIATATPGQPDATSAPAAIASIEHAVADVRSGRAAAVVTNPIAKSVLYQAGFHHPGHTEFLAELAKRDGIVPQPVMMLWCPALAVVPVTIHVSLRDAITQLTTDLIVSTARIVVKDLRERLGIAQPRLALAGLNPHAGEDGALGQEDRAVVAPAVAILRREGVDARGPLPADTMFHAAARKTYDCAICMYHDQALIPIKTIAFDEGVNVTLGLPFIRTSPDHGTAFDIAGSGQANPSSLIAALKLAAQMASAKTA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA12_CONSE
Sequence: MFTVFLLVVLATTVVSFPSDRESDGANDEARTDEPEEHGPDRNGCCRNPACESHRCG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like Sm1.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ADDB_STAA2
Sequence: MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDVLQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: CF062_PONAB
Sequence: MGDPNSRKKQALNRLRAQLRKKKESLADQFDFKMYIAFVFKEKRKKSALFEVSEVIPVMTNNYEENILKGVRDSSYSLESSLELLQKDVVQLHAPRYQSMRRDVIGCTQEMDFILWPRNDIEKIVCLLFSRWKESDEPFRPVQAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWAVGTIEDHLRPYMPE
What are the official names of this protein?
Uncharacterized protein C6orf62 homolog.
Protein: TRPA_STRZP
Sequence: MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLEDLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTYFNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGIERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQADLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ABCE_ASPFU
Sequence: MALQQVRPTNKQCRKNKKRAKAKMMESPRRLCRWAIISYEGSPRIACNATDETAESPFLRNRERSSCINRGFDISYCVRCAFTPDEHCVWEPCCAIQSVRQQVEVGTSKRTMDIYSPLQFCFRVTGLRVSAVIRLEYVQALFSQPISKVDQVSVGTVTNTITTLSNTIQQSISDKLAILFQSLALLLAAFIIAFKYSWALTLVTSSALLFVVVGCSVTLPFMTKIQQKIDKADEKHSSIAAEVFGSIRTVISLGAQESLSKRYTTWVEEARKRGNGLSLIFGIHFALVFFALYASFSLAFWFGLKLYREGHIGEINTVITVFFSVMIVVSVLGNIASPLIIVSKAASAAGSFFELIDSEKVDSGGLREPDASAHVDIIFRDVRFTYPTRPDVPVLKGLDIRFQNGKTTALVGPSGSGKSTIVALIERWYQLAMSPEDQNQGSIYVGPHDINSLDLKWWRSQIGLVQQEPFLFNDTIFNNVAFGLIGTQWEKEPDSVKKELIEKACREAFAEEFIQRLPEGYATIVGQNGIKLSGGQRQRLAIARSIVKEPKILILDEATSAIDVRGEKIVQAALDRVSRNRTTIMIAHRLSTIRRADHIVVMKGGVNVEEGTHEELLQREGGVYRDLVNAQRLELLAEEDSHTGNAVLELQDEAQSPTMSVQEKLQDEDNTQDKNRGFIRTIGLVLYEQRARWPLYVAVLISTAGAGTAFPLQSWLFAKLIEVFRFTGQKLVDAANFWALMFFLLALAVGVLYSTVGFTANSLSVRISEACRKEYFQNILAKPIPFHDLSENASGSIVSRLATDPKQVQELIGLNGAFPLISTFSMIGCIAIAFSFGWKLSLVTVFAALPCTFLAAFMRIRYELQFEAMNAAVYAGSSQFAAEAIDAFRTVSSLTMEDAILDRYTQLLREQQKKAFRKARYATLIFAFSDSVELCAMALTFWYGGQLLASREYQPTSFFVIFMAIIQGGQSAGQFFSFASNFAQAAASANRILNSRPQSDELGAASIEKQQLVRSGDLTGATVEFHDVSFRYASQDVPLFTGLNVSIQSGQFVAFVGPSGCGKTTVISLLERFYSPSQGTITFNGEDIRTLEMTSYRRELSLVAQEPRLFEGSIRENITLGLDQSEFTEEELIQACKDAEIHDFITSLPEGYATELGIKAQTSLSGGQRQRLCIARALLRKPSLLLLDEATSSLDSQSEKVVQGAMERLAQKRSLTIVAVAHRLATIQKADTIYVFGTAHAGQASRIVEQGTHQELLRAKGTYWQMVSSPRFLT
What is the function of this protein?
Pleiotropic ABC efflux transporter that may be involved in A. fumigatus adaptation to azoles such as vorizonazole.
What are the official names of this protein?
ABC multidrug transporter E.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1625_STAS1
Sequence: MTKKVAIILADEFEDIELTSPKEALENAGFETEVIGDTEKHELVGKHGEKVTVDVSIADAKPENYDALLIPGGFSPDHLRGDEEGRYGTFTKYFTQNDVPTFAICHGPLLLVDTDDLKGRTITGVINVRKDLSNAGAHVVDESVVIDNNIVTSRVPDDLDDFNREIIKKLKA
What are the official names of this protein?
Uncharacterized protein SSP1625.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
Protein: RHG06_MOUSE
Sequence: MSAQSLLHSVFSCSSPASGGTASAKGFSKRKLRQTRSLDPALIGGCGSEMGAEGGLRGSTVSRLHSPQLLAEGLGSRLASSPRSQHLRATRFQTPRPLCSSFSTPSTPQEKSPSGSFHFDYEVPLSRSGLKKSMAWDLPSVLAGSGSASSRSPASILSSSGGGPNGIFSSPRRWLQQRKFQPPPNSRSHPYVVWRSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLGCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQREEQKDASSDFVSSLLPFGNKKQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGVDVCLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNVSKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEYSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDILQTEVSFSMGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDRARGGSEKLYKVPEQYTLVGHLSSPKSKSRESSPGPRLGKEMSEEPFNIWGTWHSTLKSGSKDPGMTGSYGDIFESSSLRPRPCSLSQGNLSLNWPRCQGSPTGLDSGTQVIRRTQTAATVEQCSVHLPVSRVCSTPHIQDGSRGTRRPAASSDPFLSLNSTEDLAEGKEDVAWLQSQARPVYQRPQESGKDDRRPPPPYPGSGKPATTSAQLPLEPPLWRLQRHEEGSETAVEGGQQASGEHQTRPKKLSSAYSLSASEQDKQNLGEASWLDWQRERWQIWELLSTDNPDALPETLV
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.  Could regulate the interactions of signaling molecules with the actin cytoskeleton.  Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology (By similarity).
What are the official names of this protein?
Rho GTPase-activating protein 6, Rho-type GTPase-activating protein 6, Rho-type GTPase-activating protein RhoGAPX-1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_HALOH
Sequence: MEELINKAQTLVEALPYIRNFYGKTFVIKYGGSTMGDKRLKEKIMEDITLLKYVGVNPVLIHGGGPAISEAMESMDKEARFIQGLRITDSETMSLVEMVLVGKVNKELVSIINRLGGEAVGICGKDGGLIEADKLIFEDKSIDLGHVGSVKKINPEIVLNLIKGGYIPVISPVGSSKEGDTYNINADTVAGKLAVSLKAEKLIFLTDVDGVWSDPSNEKTRVSSLTVNEVKSWIGEGKIKGGMVPKVEACIEAVTCGVNRTHILNGLIPHALLLEIFTDRGIGTMILKER
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_STRPB
Sequence: MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAETGKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKILADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLMERPQIIVANKMDMPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATAELLAKTDEFLLYDEADLVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTNMERDESIMKFARQLRGMGVDEALRERGAKDGDPVRIGKFEFEFVD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNP3_HALS3
Sequence: MYEAVCAHPDGDSTVARLAATAASAGYDGIVVRNWGATSADPDAVGADTDADVVRGTTVSVTDRAGASERIRRRRENAVVVAARASSPSLNRFVAESERVDVLAAPMADGGDVNHVIVKAARTHGVRLEFDFAGVLRASGGDRVQALRGLRKLRELVEHYDAPFVVSGRPASHLHVRSPRELVAVGAEIGFTDAQVRAGLREWTHLAARNRRRLSAEFIAPGVKRGRYEEDP
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 3, RNase P component 3, Rpp30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S38A7_BOVIN
Sequence: MAQVSINRDLGEWGLSTDSGERARLLQSPSVDIAPKSEGEAPPGGVGGGTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGITLQMAMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIATYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGPGGSPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIIIIKYIWPDKEMTPADILNRPASWIAVFNAMPTICFGFQCHVSSVPVFNSMRQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGDAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVIEGLWLRYQGMPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLSEMEEVKPASWWAMVSYGVLLVTLGAFIFGQTTANAIFVDLLA
What is the function of this protein?
Symporter that selectively cotransports sodium ions and amino acids, such as L-glutamine and L-asparagine from the lysosome into the cytoplasm and may participates in mTORC1 activation.  The transport activity requires an acidic lysosomal lumen.
What are the official names of this protein?
Sodium-coupled neutral amino acid transporter 7, Solute carrier family 38 member 7.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=In neurons, located in soma and axons.
Protein: VDAC2_MESAU
Sequence: MADCCVRTCPRPMCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).  The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV (By similarity).  The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).  Binds various lipids, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol (By similarity).  Binding of ceramide may be required to trigger the Binding of ceramide promotes the mitochondrial outer membrane permeabilization (MOMP) apoptotic pathway (By similarity).
What are the official names of this protein?
Voltage-dependent anion-selective channel protein 2, VDAC-2, Outer mitochondrial membrane protein porin 2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Membrane. Note=May localize to non-mitochondrial membranes.
Protein: ACT4_ARATH
Sequence: MADGEDIQPLVCDNGTGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVNNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDHLMKILTERGYSFTTTAEREIVRDMKEKLSYIALDFEQELETSKTSSSVEKSFELPDGQVITIGAERFRCPEVLFQPSMIGMENPGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFGGIGDRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWIAKAEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.  This is considered as one of the reproductive actins.
What are the official names of this protein?
Actin-4.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ATPI_SACHY
Sequence: MNITPCSIKTLKGLYDISGVEVGQHFYWQIGGFQIHAQVLITSWVVITILLGSVIIAVRNPQTIPTDGQNFFEYVLEFIRDLSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIELPHGELAAPTNDINTTVALALLTSAAYFYAGLSKKGLSYFEKYIKPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: COBQ_AZOSB
Sequence: MSKASALMVQGTTSDAGKSTLVAGLARALVRRGVRVAPFKPQNMALNSAVTADGGEIGRAQALQAVAARIAPHTDFNPVLLKPSSDIGAQVIIHGKVMANLSARDYHAYKPTAMAAVMASFDRLSAQYEHVLIEGAGSPAEINLRDRDIANMGFAEAADVPVVLVADIDRGGVFAHLVGTLELLSPSEQARVRGFVINRFRGDIALLQPGLDWLTERTGRPVFGVLPYLHGLFLDAEDALANGQVAADRDGAVLKVIAPVYPRISNHTDLDALRLHPQVDFRWVGPGQAIPPADLVVLPGSKSVQADLAWLRAQGWEPALRRHLRYGGKVIGICGGFQMLGSTLADPHGLEGAPSTVAGLGALDIETVLEREKQLVNVRGRLALDGEAAVAGYEIHMGVSRGADLDRPAVLLEDGRADGALSADGQVLGTYLHGLFDTPQAVAALLDWAGLKGAAGVDLNARREADLDRLADAVEAHVDMAALFGAAWPDAA
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RL3_SACEN
Sequence: MSDRQIKGILGTKLGMTQVFDDQNRVVPVTVVQAGPNVVTQIRTPEKDGYSAVQLAFGAIDPRKVNKPRTGHFTKAGVTPRRHVVELRTADAGEYEVGQEVTAEVFEAGTVVDVVGTSKGKGFAGTMKRHGFRGQGASHGTQAVHRKPGSIGGCATPGRVFKGMRMSGRMGSDRVTTQNLKVHRVEGESGLLLIKGAIPGPKGGLVLVKSPAKGGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y2726_PHOLL
Sequence: MSHLDPTLLVLLVLAALGIISHNMTVTLAMLLLLVIRITPLNHFFPWVEKYGLTIGVLILTVGVMAPIASGKITVQAVLNSFMNWKSLLAIVIGVLVSWLGSRGVSLMSNQPSTVAGLLVGTVLGVALFKGVPVGPLIAAGILSLLIGKS
What are the official names of this protein?
UPF0756 membrane protein plu2726.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BGLL_ASPFC
Sequence: MQTLFLSLLAAAVTVHAYGSGGSNWDQAYSRAKDALQKLNQTEKVGLVTGVKWMGGPCVGNTYKPESIDYPSLCLQDSPLGIRFANPVTAFPAGINAGATWDTQLLYARGAAMGAEAKGLGIHVQLGPVAGPLGKNPNGGRNWEGFSVDPYLSGVAMEKTIRGMQDSGVQACAKHWLGNEQEHYRDTISSNIGDRAAHELYVWPFMDAVKAGVASVMCSYNKVNGTWACESDALNNKLMKEELGFPGYIMSDWNAQHSTVNSAVSGLDMTMPGSDFSNPPGSIFWGSNLEAAVADGSVPQSRLDDMVTRILAAWYLVGQDQGYPPVAFSSWNGGKANVDVTADHGTVARAVARDSIVLLKNGHGTLPLRKPKSLAIVGSDAIVNPAGPNACSDRGCNNGTLAMGWGSGTAEFPYLVGPLDAIQKRAAADGTKIVPSTTDDPTAGASAAAAAETAIVFINSDSGEGYITVEGNLGDRNNLDPWHNGNELVKAVAAASKNVIVVIHSVGPIILETILAQPSVKAIVWAGLPGQESGNALVDVIYGDTTPSGKLPYTIAKQAADYGASWINAETDDFPEGLYVDYRHFDAKGIAPRYEFGYGLSYTTFKYSGLWVNMDASAGAANGQVVPGGPADLFEVVGQVSVSVRNNGRVAGAEVAQLYLGLPDSAPATPPKQLRGFQKLMLQPGQTGRATFKLTRRDLSYWDVQQQKWVVPSGTFKVYVGSSSRDIREEGSFRVRRGW
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase L, Beta-D-glucoside glucohydrolase L, Cellobiase L, Gentiobiase L.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TMUB1_BOVIN
Sequence: MALIEGVGDEVTILFSALACLLVLALAWVSTHTAEGADPLPQPSGTPTPTQPSEAMAVTDSIRGEAPGAETPGLRHRGQAAPPEPSVGLAATPPPPDSPQEPLVLRLKFLNDSEQVARAWPHDTIGSLKRTQFPGREQHVRLIYQGQLLGDDTQTLGSLHLPPNCVLHCHVSTRVGPPLPPCPPGSEPGPSGLEVGSLLLPLLLLLLLLLWYCQIQYRPFFPLTATLGLAGFTLLLSLLAFAMYRP
What is the function of this protein?
May contribute to the regulation of translation during cell-cycle progression.  May contribute to the regulation of cell proliferation.  May be involved in centrosome assembly.  Modulates stabilization and nucleolar localization of tumor suppressor CDKN2A and enhances association between CDKN2A and NPM1 (By similarity).
What are the official names of this protein?
Transmembrane and ubiquitin-like domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Postsynaptic cell membrane. Recycling endosome. Cytoplasm. Nucleus. Nucleus, nucleolus. SUBCELLULAR LOCATION: [iHOPS]: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus, nucleolus. Nucleus. Note=iHOPS is proposed to be the shuttling form across different cellular compartments. XPO1-dependent exported from the nucleus in dividing cells. Predominantly nuclear during growth arrest.
Protein: SETD5_HUMAN
Sequence: MSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYATIIPRSDLNGLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
What is the function of this protein?
Chromatin regulator required for brain development: acts as a regulator of RNA elongation rate, thereby regulating neural stem cell (NSC) proliferation and synaptic transmission.  May act by mediating trimethylation of 'Lys-36' of histone H3 (H3K36me3), which is essential to allow on-time RNA elongation dynamics.  Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro.  The relevance of histone methyltransferase activity is however subject to discussion.
What are the official names of this protein?
Histone-lysine N-methyltransferase SETD5, SET domain-containing protein 5.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to active transcribed genes.
Protein: ECUBS_SORC5
Sequence: MHRALLCPFPATTPHPQAAQLANDCLEWTRKCGLLPDESPRTLDKVRSYSALAAHCYPDAHFERLRAICDYYSWLFFFDDVCENTSLNGAEPKVVSSLLFDVYGVLRGPTAAVGHAPFAQALADIWRRIGDGCPGFWRRRLIRHVENYIDGCVWEAQNRQLDRVPSRAVFEGMRMHTSTMYEFWDFIEYAGDLFLPDEVVEHPLVAEVRRAGNAIASFANDIYSLRKETSNRDVHNLVVVLMHEERIELEAAYARAAGIHDAQVEHFLDLVKHLPTFSATIDRNLARYVEGIRIWIRANHDWSIVTPRYNEPDAR
What is the function of this protein?
Catalyzes the cyclization of farnesyl diphosphate (FPP) to 10-epi-cubebol.  Is also responsible for the formation of many other sesquiterpenes, mainly cadalanes and cubebanes, including 1,10-di-epi-cubebol and the cadalanes delta-cadinene, T-cadinol and alpha-cadinol.
What are the official names of this protein?
10-epi-cubebol synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RS2_THEKO
Sequence: MEEYLVPLDQYLAAGVHIGTQQKTKDMKKFIYRVRQDGLYVLDVRKTDERLRVAGKFLAKFDPESILAVSVRLYGQRPVKKFGEVTGAKAIPGRFLPGTMTNPQVKNFIEPDVLIVTDPRADHQALKEAVEIGIPIVALVDTENFLSYVDIAIPTNNKGRKALALIYWILAREVLYNRKEIESREDFKIPVEDFEMRIIRT
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.