PharMolix/UniProtQA huggingface dataset:
Protein: SO5A1_HUMAN
Sequence: MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPAFGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTVSERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEESPAALEPPS
What are the official names of this protein?
Solute carrier organic anion transporter family member 5A1, Organic anion transporter polypeptide-related protein 4, OATP-RP4, OATPRP4, Solute carrier family 21 member 15.
What is the protein family that this protein belongs to?
Belongs to the organo anion transporter (TC 2.A.60) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YJA1_SCHPO
Sequence: MDLEKKPQDKVETAEIDVKEDPFLVTWQSPTDPKNPKNWIYARKWTQLILVSAFALLGPMASSMVAPCLDQIADRFHIQNSTEKALILSIYLLVFAISPMISAPLSEVFGRRMLLQVGNVIFIVFNMACGLARTKAQMYIFRFLAGFGSATPMGLGSGTISDLFTPDERGKAVAVMSLAPLLGPTIGPVVSGFIAEYTTYKWIFWSTTIFSGFIFALSLPLLAETYPKTLLGEKARKLNKSEKTNKYHTEWNLEHIPRLKLVTPALMRPIRMLFTQPIVILCSTYMAIQYGILYLVLTTYPTLWTEEYHERPSIAGLNYIASGIGLIFGSQASGIFIDKTFRYLKRRNNGKMAPEFRVPVILLGTFFFPAGLFIYGWTAQYHTHWIGPDIGAAMFNIGLMLGWRGIQTYLIDSFMIYAASSTAVACCVRSIAAFAFPLFGQDMYDTLGYGWGNSLLAFIVLGSSIITCSLLWFGGKRLRALSSMVIFKDDV
What are the official names of this protein?
Uncharacterized transporter C1529.01.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y5463_DICDI
Sequence: MKFNNAGAQGRDRGYIYSEPEFGRTRQVFY
What are the official names of this protein?
Putative uncharacterized protein DDB_G0283353.
Protein: URE2_SACEN
Sequence: MRPGEIITGDGPVPLNPGRPRVRITVVNRADRAVQVGSHYHFAAVNEGLEFDRAAAWGHRLDVPAGTAVRFEPGVEREVRLVPVGGSRRVPGLRPEYAGELDGRGHEPTAPNYGEKGQGHFE
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYNA_BACSU
Sequence: MTDQNRKELLHKTGELYKQFIENQDEQRAAKLAAVMKKAADEEVYIAFTGHYSAGKSSLLNCLLMENILPTSPIPTSANLVVIRNGEKRVRLHTTDGACAELEGTYQKDKVQQYCKDGEQIESVEIFDRYTEIDSGVAYIDTPGIDSTDDAHFLSAASILHQADALFYVVHYNHVHAEENVKFLRSIKESIPNVYFIVNQIDRHDETETKFGDYQAQVEEMLCNEGISREALYFTSVTEPDHPFNQMGALREELSRIEQQSKSNMQALTEQKVRNLLKEHTEMLKKDETGAPSFAEQLNIHTGLVQSLRDQLDEAEKQMTEAEKRMQEEINRILKNANLTPFEMRELAAAFLESQEPSFKTGFFFSKAKTAQERDKRRNAFFSDVAKRTEAEADWHMIDTLHKLAKVFDVYTAESEKLIQAYRTPLDISIIEHAVKHGAAFSSEYVLQYTKDLAELIRKEAKREAADIIKVLSAMVKERVSKDVQTINDRLVQESEKLVFLQEQARLENNAREKTDRLWAIWEEESACPMHIDTEWFKSKKTRVAAPEQKQGRSQLTAQPMPKSEIKMEQEMPLQDQIKRFYTLSDILGECSMLLKQTSAFRERVKRLEERKFTLALFGGFSSGKSSFANALVGERVLPSSPTPTTATINKITKPINGNLNKTANVVFKTEDDLTAEILQLTGIPKEPAGRSFTEKWEKAVKKNRLQEEHVKLISNFLLAYEKYQQYIQEQKKLTIPLSELKPYVAEETTACAVKEVTVYYTCPLTEKGITIVDTPGASSMNKRHTELAFQYIKDADAFFYMTYYQHSFSKGDRSFLRKLGLVKESLSMDKMFFIINAADLAKDKTELETVTDYVSAELVKEGVYEPQLFTVSSKEELVGKPESFYNQFSKVRKHLDRFIEVDVKKASAAQLSSEADKLCETVFQLHQSQHQSREEKEAQKQCLMLSFERTAADIEKRRNSKTIIEKVKKDTREQLYHIAQRLSYFANDLLKSAFHPGLQNGDWKKNVSKAMTTALHEYLFEYIQEIKTLDVRMSGFIERHINEEWLDHFQKTLNEDGYFSVYAGDQHSNGIQLKEVEPEIEERAFEQELKEIKSPKQFFEQKGKATFIEAVRMKLTKITEAWIKNEEESLISHYTAHLRRLQEDMGEKAIAQITDQKETYLRGYAEGEHAKEIEMAYQACISWKNSDNTIKM
What is the function of this protein?
Has intrinsic affinity for membranes and membrane distortion capability; causes tubulation and membrane distortion when expressed in a Drosophila cell line.
What are the official names of this protein?
Dynamin-like protein A, DynA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Found at the division septum; in the absence of minJ dispersed along membrane. Associates with the cell membrane via the D1 domain, D2 does not associate with membranes (PubMed:21205012, PubMed:23060960). In growing cells forms foci at midcell, colocalizes with FtsZ. Membrane localized in non-growing cells (PubMed:23249255). Localized uniformly along cell membrane where it is highly dynamic, DynA localizes to regions of membrane deformation upon nisin treatment and remains at those sites. Localizes into foci upon membrane potential dissipation (CCCP treatment, forms membrane pores) (PubMed:26530236).
Protein: EFTU_RHIME
Sequence: MAKSKFERNKPHVNIGTIGHVDHGKTSLTAAITKYFGEFKAYDQIDAAPEEKARGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPAIVVFLNKVDQVDDAELLELVELEVRELLSSYEFPGDDIPIVKGSALAALEDSDKKIGEDAIRELMAAVDAYIPTPERPIDQPFLMPIEDVFSISGRGTVVTGRVERGIVKVGEEIEIVGIRPTTKTTCTGVEMFRKLLDQGQAGDNIGALLRGVDRNGVERGQILCKPGSVKPHRKFKAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGIVTLPEGTEMVMPGDNVTVDVELIVPIAMEEKLRFAIREGGRTVGAGIVASIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCKX4_MOUSE
Sequence: MALRGLIRQSKVRRRREMLPQQVGFVCAVLALVCCASGLFGSLGHKTASAGKHVLLDTWRNRKLMAPINGTPLAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLVLIILYVFYILIMKYNMKMQTFFTTKQKSIANGNPVSNELEDGNDLYDGSYDDPSVPLLGQVKEKPPYGKTPVVMVDEILSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVNSKPLQNGRHENMENGNVPVENPEDPQQGQEQQPPPQPPPPEPESVETVFLSPFSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVFTFVNLPMCREDD
What is the function of this protein?
Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (PubMed:22057188).  Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived (PubMed:22057188).  May play a role in calcium transport during amelogenesis (PubMed:23375655).
What are the official names of this protein?
Sodium/potassium/calcium exchanger 4, Na(+)/K(+)/Ca(2+)-exchange protein 4, Solute carrier family 24 member 4.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm.
Protein: PPME1_MOUSE
Sequence: MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFTPVPWSQYFESMEDVEVENETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRGHGETKVKNSEDLSAETMAKDVGNVVEAMYGDLPPPVMLIGHSMGGAIAVHTAAANLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESVNKRKKEDDMETKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLIRHRFAEPIGGFQCVFPGC
What is the function of this protein?
Demethylates proteins that have been reversibly carboxymethylated.  Demethylates PPP2CB (in vitro) and PPP2CA.  Binding to PPP2CA displaces the manganese ion and inactivates the enzyme (By similarity).
What are the official names of this protein?
Protein phosphatase methylesterase 1, PME-1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: UREG_STAS1
Sequence: MTDTIKIGVGGPVGAGKTQLIEKIVKRLAKDMSIGVITNDIYTKEDEKILVNSGVLPEDRIIGVETGGCPHTAIREDASMNFAAIDELKERNDDIELIFIESGGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASLDRMAEDTKVFRGNRPFTFTNLKTDEGLDEVIQWIEQDVFLKGLA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFB4_ASHGO
Sequence: MDAIADSTFQINKSKVQLVEETPSLLTLVIDTNPKLWAEFDREVGKKGQLMQVLKSTIVFLNAHLSFNNSNQVSVIAACSRGIKYLYPQADDKEGSTKKKKSEDRSIINRNMYRGFRNVDEAVVEELYRVFQQESKQLEDGVPQPFRSTLSGAMSAGLTYINRITHETEGVSLKSRLLVITCGSSASKDEVFQYIPIMNCIFSATKMKCPIDVVKVGGVKESTFLQQATDATNGNYLHVANTDGLIQYLSTAMFIDPSLRQWVVKPNQSSVDFRTSCYLTGKVVAIGFVCSVCLCVLSIIPPGNKCPACDSEFDEKVVAKLSRKPVITGTLRKKKKKKVTK
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH subunit TFB4, TFIIH subunit TFB4, RNA polymerase II transcription factor B subunit 4.
What is the protein family that this protein belongs to?
Belongs to the TFB4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPRTL_BACC2
Sequence: MDEKEIQRLVEEVSLQYFGMPFLHKVKFNSRLRTTGGRYLLKSHNVELNYRYYEMYGKEELIGIIKHELCHYHLHITGRGYKHRDRDFRELLKKVDAPRFCKRMINEEKEKKIYKYECMECLLQYVRRRQINTKRYVCGKCKGKLKPISKTS
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEA_RICCO
Sequence: MAASFSGPSMIMEEEGRFEAEVAEVQAWWNSERFKLTRRPYTARDVVALRGNLKQSYASNELAKKLWRTLKTHQANGTASRTFGALDPVQVTMMAKHLDSIYVSGWQCSSTHTTTNEPGPDLADYPYDTVPNKVEHLFFAQQYHDRKQREARMSMSREERARTPYVDYLKPIIADGDTGFGGTTATVKLCKLFVERGAAGVHIEDQSSVTKKCGHMAGKVLVAISEHINRLVAARLQFDVMGVETLLVARTDAEAANLIQSNVDTRDHQFILGVTNPNLRGKSLATLLATGMANGKTGAELQATEDNWLAMAQLKTFPECVMDAIKNMNAGEDEKRRRMNEWMNHTSYDKCLSYEQGREIADRMGLKNLFWDWDLPRTREGFYRFKGSVMAAVVRGRAFAPHADIIWMETAKPDFAECTAFAEGVKSMHPEIMLAYNLSPSFNWDASGMTDEQMRDFIPRIARLGFCWQFITLGGFHADALVIDTFAKDYARRGMLAYVERIQREERKNGVDTLAHQKWSGANYYDRYLKTVQGGISSTAAMGKGVTEEQFKETWTRPGAMEMGSAGSEVVAKARM
What is the function of this protein?
Involved in storage lipid mobilization during the growth of higher plant seedling.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratsysase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: PURA_PHATC
Sequence: MFRHAFSKSSPAFLAGGSAIGGAIAGLMWSGERNTSSSTACDSSEPSNQSVIGLLQELSRKVNNLESLVGGNPGSFPARSTSSVTKSGTQYGIDIVLGAQWGDEGKGKLVDLLSQDYDVCARVAGGSNAGHTIVVQGKKYKFHLLPSGVLNPNATCVIGNGVVIHIPSFLNELDSLEASGVDYQGRVYISDRAHLVFDFHQEVDGRQEDRLGRHKIGTTKKGIGPAYSSKINRNGLRVGDLQNWDHFERRFRELCTHHERSYEGLKIDVDNQLAFYKTVAERVNSMTIDTIDYTNKQFEAGKRILVEGANATMLDIDFGTYPYVTSSNPSVGSVLTGLGVSPGKLRGIYGTVKAYCTRVGEGPFPTELPLDEGTPGEHLSQVGAEYGTTTGRTRRCGWLDIPQMKYSALINGFTSINLTKVDVFTGMPEVKIGKAYLHNGKYLSSMPASLDVLSNVGVEYEVLPGWSEDISNCKKFEELPENCQKYILRVQELLGIPIRWIGVGPNRADVIDRGEGWDLATAGTNQ
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLR26_PLAHL
Sequence: MTGILCFPPFARFFMLLSGCAWLAGVSSGTSLVASAFSDENQLSEFVHVAEIAQIHRNLRGHINSAIIEANDTSEERMQPNNVVGEGKAPSGAQETVAQILVKGMNKVADFLKDLTRSQK
What is the function of this protein?
Secreted effector that does not suppress pattern-triggered immunity (PTI) in plant host.
What are the official names of this protein?
Secreted RxLR effector protein RXLR-C26.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: GLYA_RHOPB
Sequence: MSASAKPAAKSAATASAPDSFFSATIADADPEIAAAIAGELGRQRHEIELIASENIVSRAVMEAQGSVMTNKYAEGYPGHRYYGGCEFVDVAENLAIERAKKLFGAGFANVQPNSGSQMNQAVFLALLQPGDTFMGLDLAAGGHLTHGSSVNMSGKWFKPVHYGVRREDGIIDMDEVAKIAEANKPKLIIAGGSAYSRAWDFKRFREIADSVGAYFMVDMAHFAGLVAGGVHANPVPHAHVVTTTTHKSLRGPRGGLILTNDEALAKKFNSAIFPGLQGGPLMHVIAAKAVAFKEALQPDFKVYAKNVVENAKALAETLRGHGFDIVSGGTDNHLMLVDLRPKSLKGNVSEKALVRAGITCNKNGIPYDPEKPFVTSGIRLGTPAATTRGFGVAEFQQVGGMIAEVLNAIAQSEDGTAPLVEAAVKARVKELTDRFPIYQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_CORGL
Sequence: MDFKVADLSLAEAGRHQIRLAEYEMPGLMQLRKEFADEQPLKGARIAGSIHMTVQTAVLIETLTALGAEVRWASCNIFSTQDEAAAAIVVGSGTVEEPAGVPVFAWKGESLEEYWWCINQIFSWGDELPNMILDDGGDATMAVIRGREYEQAGLVPPAEANDSDEYIAFLGMLREVLAAEPGKWGKIAEAVKGVTEETTTGVHRLYHFAEEGVLPFPAMNVNDAVTKSKFDNKYGTRHSLIDGINRATDMLMGGKNVLVCGYGDVGKGCAEAFDGQGARVKVTEADPINALQALMDGYSVVTVDEAIEDADIVITATGNKDIISFEQMLKMKDHALLGNIGHFDNEIDMHSLLHRDDVTRTTIKPQVDEFTFSTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFADQTIAQIELFQNEGQYENEVYRLPKVLDEKVARIHVEALGGQLTELTKEQAEYIGVDVAGPFKPEHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YD22A_YEAST
Sequence: MESQQLHQNPHSQHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQEETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQDQHSEVPQAKTKVRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYSDILTVLCKSVSKMQTNNQELKDWIALANLEYNGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNSDHINESTVSSQYLSDDNELSLRPATERI
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty2-DR2 Gag polyprotein, TY2A, TYA, Transposon Ty2 protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LANLA_BACLI
Sequence: MSKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGGTITLSTCAILSKPLGNNGYLCTVTKECMPSCN
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.  When present individually, LchA1 exhibits activity towards B. subtilis L1 (IC(50)=9 uM), Rhodococcus sp.  SS2 (IC(50)=9 uM), M. luteus B1314 (IC(50)=1. 2 uM), B. megaterium VKM41 (IC(50)=1. 8 uM), S. aureus 209p (IC(50)=3. 1 uM), B. pumilus 2001, B. globigii I, B. amyloliquefaciens I, M. smegmatis 1171 and M. phlei 1291.  However, when combined with LchA2, it displays much stronger activity against B. subtilis L1 (IC(50)=0. 64 uM), Rhodococcus sp.  SS2 (IC(50)=0. 64 uM), M. luteus B1314 (IC(50)=0. 09 uM), B. megaterium VKM41 (IC(50)=0. 12 uM) and S. aureus 209p (IC(50)=0. 64 uM).  The activity of the combined LchA1 and LchA2 peptides is strongest at a molar ratio of 1.  Even when applied at 17-fold concentration of the highest IC(50) values for Gram-positive bacteria, neither the individual nor the combined peptides display activity against Gram-negative bacteria P. aeruginosa PAO1, P. putida I-97 or E. coli C600.
What are the official names of this protein?
Lantibiotic lichenicidin VK21 A1, LchA1.
What are the subcellular locations of this protein?
Secreted.
Protein: UNG_THEFY
Sequence: MVSAMPRPLHEIMESGWAEALEPVADRIAQMGDFLRQEVAEGRTYLPAGENVLRAFQQPFDQVRVLLVGQDPYPTPGHAVGLSFSVSPEVRRLPGSLRNIFLEYTQDLGYPMPSSGDLTPWAERGVLLLNRVLTVTPRKPGSHRGKGWEAVTDQAIRALAARGKPLVAILWGRDARSLRPLMPDVPCVESAHPSPMSAHHGFFGSRPFSRANALLEQQGAEPMDWRLP
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_PSEPW
Sequence: MARVKRGVIARKRHKKILKLAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRQKKRQFRALWIARINAGARTNGLSYSRLIAGLKKASIEIDRKVLADLAVNEKAAFAAIVEKAKAVLA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ACCD_BRUSU
Sequence: MNWITNYVRPKINSMLGRREMPENLWIKDPSTGEMVFHKDLESNQFVIPSSGHHMRIKAKDRLRFFFDNGEYTTLEAPKVPLDPLKFRDEKKYIDRLKDYRSRTGMDDAIVNGLGTIEGLPIVATVQDFSFMGGSLGMGAGEAIIQGFEKAIELKRPLVLFASSGGARMQEGILSLMQLPRTTVAVEMLKEAGLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGALIGFAGPRVIEQTIREKLPEGFQSSEYLMEHGMVDMVVSRLELKATIARLLKIMTKQPANSDAPAPQKPDADSKAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DKSA_CAUVN
Sequence: MQTATVLVEKSDYRPSEDEPFMNDRQLEYFKQKLLAWKEEILRESRETVSHLQKETENHADLADRASSETDRALELRTRDRQRKLISKIDQALRRVEDGSYGYCEETGEPIGLARLEARPTATMSVEAQERHERRERVHRDD
What is the function of this protein?
Transcription factor that acts by binding directly to the RNA polymerase (RNAP).  Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
What are the official names of this protein?
RNA polymerase-binding transcription factor DksA.
What is the protein family that this protein belongs to?
Belongs to the DksA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_SHESR
Sequence: MQGSVTEFLKPRLVDIEQVNSTRAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSKEGVQEDILEILLNLKGLAVTIEGKDEAMLTLSKSGAGPVIAADITHDGDVTIVNPDHVICHLTGNNDISMRIRVERGRGYVPASARAQTEDDDRPIGRLLVDASFSPVARIAYNVEAARVEQRTDLDKLVIDMTTNGTIDPEEAIRRSATILAEQLDAFVELRDVTEPEMKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASLADDL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RNFD_BUCAI
Sequence: MNFPCIYHVYSIRKIMFLVIVACLPGIFAKYYFFGIGTLIQIFFSIFISLVLEIIILKIRSKNIKNYLQDTSLVLTSVLFGVSIPPLLPWWMTSIGLFFAIVVAKHLYGGIGQNIFNPAMVGYAVLLISFPVYMNNWNERDFSLSFFNDFKKSAYIIFFKNDITTVSSSYLNIIPDAFTTATPLNNFKIKSHLKDDFFLKENIIKNKEVSIQTSWKCINISFFLGGIFLLFTKIICWRIPISFLSSLGMLSIITYFYSKELFMSPQVHFFSGGTMICAFFIATDPVTAACNNVGKIVFGIIIGFLVWIIRNYSDYPDAIAFSVLFANMTVPLVDYYTKSSGYGRNNI
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FTSZ2_PYRFU
Sequence: MLEKLLEQAGIKLDFDGEEEKKSEIVDEFSGYKINIAVVGVGGSGNNTISRLYDLGVQGADLIAMNTDAQHLAITKAHKKVLLGKHITQGKGSGGDPKVGYLAAEASAQEIAAAVDGYDLVFITAGMGNGTGTGAAPVVARIVKETARNNGRFQEPLVVSVVTFPFKTEGTVRIEKAKWGIQRLLEYSDTVIIIQNDKLLELVPKLPLQSAFRFADELIARMVKGIVETIKLNSIVNIDFADVYSIMKGGGPALIGIGESDSNNRAVDAVNNALTNKMLDVEFGSGEKALVHFTIGPDVSLEEINKAMEVVYEKLSEKSEIKWGAMVDPEMGKTVRAMVIMTGVRSPYILGNVNALTDSSSWVVPKDRRLIGDPRIEKMFPDFNGSRAGRKRPSVGDAILKELGFKEL
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ 2.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.