PharMolix/UniProtQA huggingface dataset:
Protein: PP302_ARATH
Sequence: MNKNMLVRSARPTLASIHRLFSAAAAATVDTATAPVVKPRSGGGKGGESANKKETVVGGRDTLGGRLLSLVYTKRSAVVTIRKWKEEGHSVRKYELNRIVRELRKIKRYKHALEICEWMVVQEDIKLQAGDYAVHLDLISKIRGLNSAEKFFEDMPDQMRGHAACTSLLHSYVQNKLSDKAEALFEKMGECGFLKSCLPYNHMLSMYISRGQFEKVPVLIKELKIRTSPDIVTYNLWLTAFASGNDVEGAEKVYLKAKEEKLNPDWVTYSVLTNLYAKTDNVEKARLALKEMEKLVSKKNRVAYASLISLHANLGDKDGVNLTWKKVKSSFKKMNDAEYLSMISAVVKLGEFEQAKGLYDEWESVSGTGDARIPNLILAEYMNRDEVLLGEKFYERIVEKGINPSYSTWEILTWAYLKRKDMEKVLDCFGKAIDSVKKWTVNVRLVKGACKELEEQGNVKGAEKLMTLLQKAGYVNTQLYNSLLRTYAKAGEMALIVEERMAKDNVELDEETKELIRLTSQMRVTEISSTIS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g02820, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPOC1_PLAOC
Sequence: MIDRYKHQQLRIGSVSPQQISAWAKKILPNGEIVGEVTKPYTFHYKTNKPEKDGLFCERIFGPIKSGICACGNYRVIGDEKEDPKFCEQCGVEFVDSRVRRYQMGYIKLACPVTHVWYLKRLPSYIANLLDKPLRELEGLVYCDFSFARPIAKKPTFLRLRGSFEYEIQSWKYSIPLFFTTQGFDTFRNREISTGAGAIREQLADLDLRIITAYSLVEWKELGEEGPTGNEWEDRKIGRRKDFLVRRMELAKHFIRTNVEPEWMVLCLLPVLPPELRPIIQIDGGKLMSSDINELYRRVIYRNNTLTDLLTTSRSTPGESVMCQEKLVQEAVDTLLDNGIRGQPMRDGHNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPREIAIELFQTFVIRGLIRQHLASNIGVAKSKIREREPIVWEILQKVIQGHPVLLNRAPTLHRLGIQAFQPILVEGCAICLHPLVRKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSPAIGDPISVPTQDMLMGLYVLTIGNRRGICANRYNPRNRRNYQNERIDDNNYRYTKEKEPYFCSSYDALGAYRQKRINLDSPLWLRWRLDQRVIASREVPIEVQYESLGTYHEIYGHYLIVRSVKKEILCIYIRTTVGHISFYREIEEAIQGFCRACSYGT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYY_KINRD
Sequence: MNDVWDELQWRGLVAHSTDEAALQEALQTGPLTYYVGFDPTAASLHVGHLVQVLTAKRLQQAGHRPLILVGGATGLVGDPRPSAERTMNDPSVVAGWVTGLQGQIAPFLDFDGPAAATMVNNLDWTQSMSTIEFLRDVGKHFSVNRMLDREAVSKRLATTGISFTEFSYVLLQSNDYLQLHRRHGCTLQLGGSDQWGNITAGCELVRRVDQRTVHALATPLLTKADGTKFGKTESGAVWLDPELTSPYAFHQFWLNAEDAKVVDYLKAFSFRPREEIEELGRQAVENPRARAAQRALAHEVTALVHGEEAAVAVEAAAAALFGGSDLEAIDERILRGALAELPTAAPADRDVRLAQLFADTGLAPSLSGARRTIGEGGAYVNNIKLTDPEATLRDVQLLHGRYAVLRRGKKSLASVAVPLPQ
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK1_PETCR
Sequence: NGTCAWLRPDGKTQVTVEYQNDHGAMVPIRVHTILISTQHDETVTNDEIAADLKEHVIKPVVPENYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASGLARRCIVQVSYAIGVPEPLSVFVDTYGTGKIPDREILKIVKETFDFRPGMISINLDLKRGGNGRFLKTAAYGHFGREDPDFTWEVVKPLKWEKA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPCD_BOVIN
Sequence: MAVTGWLESLRAAEKTALLQDGRRKVHYLFPNGKEMAEEYDEKTNELLVRKWRVKSALGALGQWQIEVGEPALPGAGSLGPELITESNANPIFVRKDTKMSFQWRIRNLPYPKDVYNVFVDQKERCVVVRTTNKKYYKKFSIPDLERYQLPLDESLLSFAHANSTLIISYQKPKEVLVAESELQKELKKVKTAHSSDGDCKTQ
What is the function of this protein?
May play a role in the formation or function of ciliated cells.
What are the official names of this protein?
Protein DPCD.
What is the protein family that this protein belongs to?
Belongs to the DPCD family.
Protein: AMZA_SACS2
Sequence: MTEMKILIVTLTYIEKSIIDEIVNNLSSYGLEVDILLDSRKYLPISAFNWERLQYDAEKVLSFLKSIHDFNYDSIIFLADSDGYIDGYNFVFGLTIDNFAIIFLHRLREEFYNRKPDLDLFMKRVVKEVTHEVGHTLGLSHCNTTGCVMNFSNSVEDVDKKQAKFCKNCAHKIEKLSKYLQQK
What is the function of this protein?
Probable zinc metalloprotease whose natural substrate is unknown.
What are the official names of this protein?
Archaemetzincin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M54 family.
Protein: GCH4_XANC5
Sequence: MSATLPDVAVTEPSTLSAPLRWVGMQDIAIPVQLEAGGGQLAARASVQVDLPRAELKGIHMSRLYRLLDTQLQQPVSPAMLSGLLQALIESHADCASRAARLTLSGELMLRTPALRSEGLSGWRAYPVHIAAQCSAGRTTIQLQAEVLYASTCPCSAALSRQLLSDAFVQQHAGRDALALDEVAQWLQDHGSYATPHSQRSVAQVRVELPADAQRLAIRQLVGLCEQALATPVQAAVRRPDEQAFARLNGANLMYVEDAARRLRQQLAEHYAAFHVAVRHLESLHAHDAVAETDSDDAVLGPTTM
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: TRPB_CALS4
Sequence: MKGRFGRFGGQYVPETVMNALIELEREFEEAKKDEKFMEEYRYYLKEYSGRPTPLYYAENLTKRLGGAKIYLKREDLNHTGAHKINNVLGQVLLAKRMGKKRIIAETGAGQHGVATATAAAMFGMECEIFMGEEDIKRQALNVFRMKLLGAKVTAVTSGTRTLKDAVNEAIRDWVTNIETTFYVIGSVVGPHPYPTMVRDFQRVIGDETKEQILEKEGRLPDYVVACVGGGSNAMGIFYPFIEDKGVKLVGVEAAGEGIETGKHASAMAKGSVGVLHGMMTYLLQDEEGKILPVHSISAGLDYPGVGPEHAYLKEIGRAEYVYATDEEALAAFMDLSRTEGIIPALESAHALAYAMKLAKKLDEDKIIVVNLSGRGDKDVNTVAKVMGVEL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: 3MGH_CLOB8
Sequence: MILNKEFYKQGALILAKELLGKVIIRKVDGVTLRAKIVETEAYIGEIDKASHAYNGRRTERTEPLFREGGIAYVYFIYGKYYCFNVISGLEDKGEGVLIRAFEPLNEFDYLAKKRFNQNYDELSETKKKAITNGPSKLCIAFSIDKSENYKRLYDEGDFYIEEGEKDTFKIVETKRIGIDYAEEAIDFPWRFYIEGNKYISKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: ASSY_LISMC
Sequence: MAKEKIVLAYSGGLDTSVAIQWLVESGYEVIACCLDVGEGKNLDFIKEKAITVGASESYTIDAKEEFAEDFALIALQAHAYYEGKYPLISALSRPLIAKKLVEVARQEGASAIAHGCTGKGNDQVRFEVAIHALAPDLKVVSPVRDWKWSREEEINYAKEHNIPVPIDLDNPFSIDQNLWGRSNECGVLENPWTTPPEAAYDLTVSLEDAPDTPDIVEITFDAGIPISLNGENMSLANLILTLNEIAGKHGVGRIDHIENRLVGIKSREVYECPAAVTLITAHKELEDLTFVREVAHFKPIIEQKISETIYNGLWFSPLTEALVAFLKSTQKFVNGTIRVKLFKGHAIVEGRKSPNSLYDENLATYTSSDTFDQDAAVGFIKLWGLPTKVSAEVNSKVTITTEV
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_PSYCK
Sequence: MQEPSEDQATSDELSFVHDAVLLQEAVAAVLGVKALPKQTDDESQNSLQASGIYVDATFGRGGHSRLLLSQLADDATLIVFDKDPTAISVARELANSDSRVKVVHDSFATLTDSLAAMRITQVDGLMADLGISSPQIDDGSRGFSFMRDGAVDMRMDTSRGQSVAEWLETVDDETLANVLYEFGEERHSRRIARAIKQMDSYDSTLALAEVIKVAHPNWQRGKHPATQSFQAMRIFINNELGDVDNFLEQSIPILKVGGQLAVISFHSLEDRRIKQFLQRHSKGQYPEDENLPMPPKRPRYFSKPKRVGPSKAEISHNPRSRSAWLRMATRTDADYVADIHP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB5L_MIMIV
Sequence: MTYNYLLILIIIYVIKIICRYFKQKNELQMESKTNLDSSKLVDPINQVNQINQVNQVNQTNQTDKIIVSFRGDKYDITDFLRKHPGGKNILIKNNGKDIEELMAEYEHSKNAYLILSKYKITEK
What is the function of this protein?
Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
What are the official names of this protein?
Cytochrome b5-like protein.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ZN480_HUMAN
Sequence: MLCDEKAQKRRKRKAKESGMALPQGHLTFRDVAIEFSQAEWKCLDPAQRALYKDVMLENYRNLVSLGISLPDLNINSMLEQRREPWSGESEVKIAKNSDGRECIKGVNTGSSYALGSNAEDKPIKKQLGVSFHLHLSELELFPDERVINGCNQVENFINHSSSVSCLQEMSSSVKTPIFNRNDFDDSSFLPQEQKVHLREKPYECNEHSKVFRVSSSLTKHQVIHTVEKPYKCNSCGKVFSRNSHLAEHCRIHTGEKPYKCNVCGKVFSYNSNFARHQRIHTREKPYECNECGKVFSNNSYLARHQRIHAEEKPYKCNECGKGFSHKSSLANHWRIYTGEKPYKCDECGKAFYRIALLVRHQKIHTGEKPYKCNECGKVFIQNSHLAQHWRIHTGEKPYKCNECGKVFNQLSNLARHRRIHTGEKPYKCNECGKAFSEYSGLSAHLVIHTGEKPYKCSECGKAFRHKLSLTNHQRIHTGERPYKCNECGKVFNRIAHLARHRKIHTGEKPYKCNECGKAFSRISYLAQHWTIHMG
What is the function of this protein?
Involved in transcriptional regulation as an activator.
What are the official names of this protein?
Zinc finger protein 480.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PEPQ_SHEDO
Sequence: MDQLAHHFSEHIVELNRRVAEIIAREKLSGLVIHSGQHHRQFLDDMNYPFKVNPQFKAWVPVIDNPNCWLIVNGRDKPTLVFYRPVDFWHKVSDVPDAFWTEHVDIKLLTKADRVAEFLPKDITNWAYLGEHLDVADVLGFTSRNPDAVMNYLHYHRASKTQYELECMRQANKIAVKGHQAAKNAFYNGGSEFEIQQQYLSSVGQTVNEVPYGNIVALNQNAAILHYTALEHTKPAQRLSFLLDAGANFHGYASDITRTYAFEKNSFCDLISALNAVELAIIDRIKPGVKYTDLHIETHHHIAQLLLDFNLATGDAAGLVDQGITNVFFPHGLGHMLGLQVHDMGGYLHDERGTHIPAPEAHPYLRCTRTLEANQVLTIEPGLYIIDSLLDELKQDSRKQQINWDQVAHFRPFGGIRIEDNVIVHQDRNENMTREFGLID
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: RBS_SYNE7
Sequence: MSMKTLPKERRFETFSYLPPLSDRQIAAQIEYMIEQGFHPLIEFNEHSNPEEFYWTMWKLPLFDCKSPQQVLDEVRECRSEYGDCYIRVAGFDNIKQCQTVSFIVHRPGRY
What is the function of this protein?
Beta-carboxysome assembly initiates when soluble RuBisCO aggregates is condensed into a liquid matrix in a pre-carboxysome by the RbcS-like domains of probably both CcmM58 and CcmM35.  CcmN interacts with the N-terminus of CcmM58, and then recruits the CcmK2 major shell protein via CcmN's encapsulation peptide.  Shell formation requires CcmK proteins and CcmO.  CcmL caps the otherwise elongated carboxysome.  Once fully encapsulated carboxysomes are formed, they migrate within the cell probably via interactions with the cytoskeleton.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Carboxysome. Note=In the carboxysome RuBisCO is organized into a paracrystalline array (PubMed:28616951). This cyanobacterium makes beta-type carboxysomes (PubMed:22928045).
Protein: SPTC1_CRIGR
Sequence: MAMAAEQWVLVEMVQALYEAPAYHLILEGILILWIIRLVFSKTYKLQERSDLTAKEKEELIEEWQPEPLVPPVSKNHPALNYNIVSGPPTHNIVVNGKECVNFASFNFLGLLANPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMRTEEAIIYSYGFSTIASAIPAYSKRGDIVFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTVCPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGISIDDIDLISANMENALASVGGFCCGRSFVVDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKKKCQHIHKSLQGISGLKVVGESLSPALHLQLEESTGSREKDVQLLQEMVIHCMNEGIALTQARYLDKEEKCLPPPSIRVVVTVEQTEEELERAASTIREAAQAVLL
What is the function of this protein?
Serine palmitoyltransferase (SPT).  The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core.  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference.  The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA.  The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference (By similarity).  Required for adipocyte cell viability and metabolic homeostasis (By similarity).
What are the official names of this protein?
Serine palmitoyltransferase 1, Long chain base biosynthesis protein 1, LCB 1, Serine-palmitoyl-CoA transferase 1, SPT 1, SPT1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NDNF_DROME
Sequence: MQRSTMLPGVELLLLFLLSTSLHAEISHLPMASNRIILDSTELLQNPLIQDAGVPAARATPLPPQKCPSLQRYRKMLKDFDDLEDLYVDVPVHIALAERQRKRFVLNLNDSTPLTIRFSAPVGRKMYYNQTGNPLRPAAVAPGPGVAVGSLVLPCALRGQYDLFVLARHSGALKVDALAEHPQHDWPLLNATHRIAIRTQNRVRKREMIVKWERSKFDFHVMHYCLVIQRLSMDTPRMIFTNFCQAVSAYTDQQPMTPSCAAGGPLEGIWGAPPQRERRLNPRQNVHIVCTGKRRQQLLRRLLPRSSYHLDLFGIHQGRQNLTLRLASSQVNFNRTQPLALKQQALMQLKIGGQHGKQVYSFKVPQTTRQLGEPFMRHLLIPCSGSEIRVKLLRQRSEVGKTEAFYSPTYIRQKGVLPGERYLMRFEPSNDDEALRAQKVMVALSSEALFRDLPELPQNTTVFNVRTRCSRATIAWNGSPDERELSYCIIVFNLPQRNRSVVDFTNYCMDFVPKRVMQYRYFEWMTCRERQQSPDNIETETILNLMPGSSYLVYVTANLSMGKPLPYQALTLHMASQCLDGSHESFY
What is the function of this protein?
Secretory protein that acts as a feedback regulator of dpp/BMP, wg and hh signaling pathways (PubMed:35609633, PubMed:35037619).  In the developing wing, is a dosage-dependent modulator of dpp/BMP signaling involved in wing growth and crossvein patterning; low levels promote and high levels inhibit dpp/BMP signaling (PubMed:35609633, PubMed:35037619).  In the early pupal wing, inhibits dpp/BMP signaling activity to prevent the formation of ectopic crossveins in the posterior compartment (PubMed:35609633, PubMed:35037619).  Binds to dpp and gbb to modulate their release and activity decreasing dpp/BMP signaling in the responding cells (PubMed:35609633, PubMed:35037619).  During wing development regulates dpp/BMP coreceptor dally availability on the cell surface (PubMed:35609633).  Might have a role in testis development (PubMed:35609633).
What are the official names of this protein?
Protein NDNF, Neuron-derived neurotrophic-like factor, Protein Nord.
Protein: FABI2_RHIME
Sequence: MNGLMNGKRGLIMGVANSHSIAWGIAKSLAAQGAELAFTYQGEALGKRVKPLAAEVNSDFLLPCDVEDIGSVDAVVDAIKERWGKLDFVVHAIGFSDKNELKGLYADTTRDNFSRTMVISCFSFTEIAKRAAELMSEGGTMLTLTYGGSMRVMPNYNVMGVAKAALEASVRYLAADYGSRGIRVNAISAGPIRTLAGAGISDARAMLSWQQKNSPLRRTVTIEDVGSSALYLLSDLSRGVTGEIHYVDSGYNITSMPTLEALRVADAD
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] 2, NADH-dependent enoyl-ACP reductase 2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YL531_MIMIV
Sequence: MVKNQYISQNMENKEIENKEIENKKTDSKEFDKEIVSCLIKIVETIDSIKPIDPEILNKKDLDLFDLMMPLAESCGMGWYYKQLQTECKSNKEIKLQNKQQENSEEKNSEEKNSEEKNSEEKRMLEILNSNLPTEGKIIIVNATNGKERKAFYTWADYHNLSHQPTRIDLFDDTFIFKCEECGESNYDDDMRYQSDWSTINPGACYGSFIKCPNYCDTFIHTEDYDPYGGIKRMIAFNAIIIGHDIPKLSRKTTKRKHNKQGLSSNDLSVFNDTPVRDFIVMDLNDFHSKFKSKDNGYVKINDE
What are the official names of this protein?
Uncharacterized protein L531.
Protein: PROF_HELAN
Sequence: MSWQAYVDEHLMCDIEGTGQHLTSAAILGLDGTVWAQSAKFPQFKPEEMKGIIKEFDEAGTLAPTGMFIAGAKYMVLQGEPGAVIRGKKGAGGICIKKTGQAMIMGIYDEPVAPGQCNMVVERLGDYLLEQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin, Pollen allergen Hel a 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PTH_CHLTA
Sequence: MVKLVVGIGNPGRQYVWTRHNIGFLLLDSLASRFLGAFREAPRLYASFAKVEISSEAVVLMKPTTYVNLTGKAVLAAKKFFDVSMEDILVVADDINREFGFVRFRQDCGSGGHNGIKNTTQILQSNHYWQLRLGVGRPSYPGAEGVADYVLSSFSLNEKEKLNDFLEKGIEEILPWLGC
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATL69_ARATH
Sequence: MSPISPPASGVGLGYGIAIAVSILVLISFIMLASYICIRSKSTGRDEATSDVVLDLPSPAAEVKLGLDRPVIESYPRIVLGDSRRLPRPNNGPCSICLCDYEAREPVRCIPECNHCFHTDCVDEWLRTSATCPLCRNSPAPSRLATPLSDLVPLAFQIR
What are the official names of this protein?
Putative RING-H2 finger protein ATL69, RING-type E3 ubiquitin transferase ATL69.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KDKA_MANSM
Sequence: MLQVQHENHFFLFNFDENRPNQEHFFESYFWQKQNRIIGSAKGRGTTWFIQSQDLFGVNTALRHYYRGGLWGKINKDRYAFSSLEETRSFAEFNLLNRLYQAGLPVPKPIGAHVEKLAFNHYRADLLSERIENTQDLTALLPNTELTAEQWQQIGKLIRRLHDLQICHTDLNAHNILIRQQNNDTKFWLIDFDKCGEKPGNLWKQENLQRLHRSFLKEVKRMRIQFSEKNWADLLNGYQN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase, SPS1 protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NFYB_CHICK
Sequence: MDGDSSTTDASQLGIAGDYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGTVTTGDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQQIQFS
What is the function of this protein?
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.  NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
What are the official names of this protein?
Nuclear transcription factor Y subunit beta, CAAT box DNA-binding protein subunit B, Nuclear transcription factor Y subunit B, NF-YB.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYSA2_SHEON
Sequence: MSIHIQQVNKHFGNFVAVDSVNLEIKTGELTALLGPSGSGKTTLLRIIAGLEQADSGIVKFNGEDITTQHVSERGVGFVFQHYALFKHMTVFENVAYGLTVRPRKTRPSKAEIAEKVHSLLKLVQLDWTADRYPSQLSGGQRQRIALARALAVEPKVLLLDEPFGALDAKVRAELRRWLRRLHDEINVTTVFVTHDQEEALEVADKIVVMNKGRIEQQGTPEEVYDTPSNPFVYEFLGNVNLFHARVKHGHSTIGNIHIPSPEHAGGEEQQGLAYVRPHEIEVLTQPTENAIKVNLDLVTIVGPVARLEVLTEIDEQLIHVELSKVQFKQLGISKGDNAWIQPRYSKVFLGEGI
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA 2, Sulfate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ACY1B_RAT
Sequence: MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYTRGAQDMKCVSIQYLEAVKRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRHEFHALRAGFALDEGLANPTDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVNLTKLEGGVAYNVVPATMSACFDFRVAPDVDMKAFEEQLQSWCQEAGEGVTFEFAQKFTEPRMTPTDDTDPWWAAFSGACKEMTLTLEPEIFPAATDSRYIRAVGIPALGFSPMNRTPVLLHDHNERLHEAVFLRGVDIYTRLVAALASVPALPGES
What is the function of this protein?
Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).
What are the official names of this protein?
Aminoacylase-1B, ACY-1B, ACY IB, N-acyl-L-amino-acid amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_SALPL
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYGLEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAVAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHXXXXXXXXXXKNHGMHFRVLAKALRMSGGDHVHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVAVEACVQARNEGRDLAREGNXIIREAS
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PGM2_YEAST
Sequence: MSFQIETVPTKPYEDQKPGTSGLRKKTKVFKDEPNYTENFIQSIMEAIPEGSKGATLVVGGDGRYYNDVILHKIAAIGAANGIKKLVIGQHGLLSTPAASHIMRTYEEKCTGGIILTASHNPGGPENDMGIKYNLSNGGPAPESVTNAIWEISKKLTSYKIIKDFPELDLGTIGKNKKYGPLLVDIIDITKDYVNFLKEIFDFDLIKKFIDNQRSTKNWKLLFDSMNGVTGPYGKAIFVDEFGLPADEVLQNWHPSPDFGGMHPDPNLTYASSLVKRVDREKIEFGAASDGDGDRNMIYGYGPSFVSPGDSVAIIAEYAAEIPYFAKQGIYGLARSFPTSGAIDRVAKAHGLNCYEVPTGWKFFCALFDAKKLSICGEESFGTGSNHVREKDGVWAIMAWLNILAIYNKHHPENEASIKTIQNEFWAKYGRTFFTRYDFEKVETEKANKIVDQLRAYVTKSGVVNSAFPADESLKVTDCGDFSYTDLDGSVSDHQGLYVKLSNGARFVLRLSGTGSSGATIRLYIEKYCDDKSQYQKTAEEYLKPIINSVIKFLNFKQVLGTEEPTVRT
What is the function of this protein?
Major phosphoglucomutase isozyme that catalyzes the reversible interconversion of glucose 1-phosphate and glucose 6-phosphate (PubMed:5784209).  Constitutes about 80-90% of the phosphoglucomutase activity in the cell (PubMed:14264884, PubMed:5231755).  Key enzyme in hexose metabolism.  The forward reaction is an essential step in the energy metabolism of galactose since the product of the galactose pathway enzymes in yeast is glucose 1-phosphate.  The reverse reaction is an essential step for biosynthesis when carbon sources other than galactose are the energy source because glucose 1-phosphate is the starting point for the synthesis of UDP-glucose, which acts as a precursor for the synthesis of oligosaccharides and trehalose (PubMed:14264884).
What are the official names of this protein?
Phosphoglucomutase 2, PGM 2, D-glucose-1,6-diphosphate:D-glucose-1-phosphate phosphotransferase, Glucose phosphomutase 2.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.