PharMolix/UniProtQA huggingface dataset:
Protein: PLA17_ARATH
Sequence: MASLSLPITLKNPRFFSSSPQNIFKTQPQTLVLTTKFKTCSIICSSSCTSISSSTTQQKQSNKQTHVSDNKREEKAEEEEEEKEVSLREIWREVQGCNNWEGQLDPMNNHLRREIIRYGEFAQACYDSFDFDPHSKYCGSCKYHPSDFFLNLDLHLHKGYTITRYLYATSNINLPNFFQKSKLSSIWSQHANWMGFVAVATDEEEVSRLGRRDIVIAWRGTVTYLEWIYDLKDILCSANFGDDPSIKIELGFHDLYTKKEDSCKFSSFSAREQVLAEVKRLIEYYGTEEEGHKTSITVTGHSLGASLALVSAYDIAELNLNHVPENNYKIPITVFSFSGPRVGNLRFKERCDELGVKVLRVVNVHDKVPSVPGIFTNEKFQFQKYVEEKTSFPWSYAHVGVELALDHKKSPFLKPTKDLGCAHNLEALLHLVDGYHGKDEEAEKRFCLVTKRDIALVNKSCDFLRGEYHVPPCWRQDENKGMVKNGDGQWVLPDRPLLEPHGPEDIAHHLQQVLGKVNDDNFKPTTT
What is the function of this protein?
Acylhydrolase that catalyzes the hydrolysis of phosphatidylcholine at the sn-1 position.  Moderate activity toward phosphatidylcholine (PC), monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG) and triacylglycerol (TAG).
What are the official names of this protein?
Phospholipase A1-Igamma3, chloroplastic, DAD1-like lipase 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
Protein: AFG32_MOUSE
Sequence: MAHRCLLLWSRGGCRRGLPPLLVPRGCLGPDRRPCLRTLYQYATVQTASSRRSLLRDVIAAYQRFCSRPPKGFEKYFPNGKNGKKASEPKEAVGEKKEPQPSGPQPSGGAGGGGGKRRGKKEDSHWWSRFQKGDFPWDDKDFRMYFLWTALFWGGVMIYFVFKSSGREITWKDFVNNYLSKGVVDRLEVVNKRFVRVTFTPGKTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENRVPVVYIAESDGSFLLSMLPTVLIIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSALEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDAINEKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKGLGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARMIDDEVRILISDAYRRTVALLTEKKADVEKVALLLLEKEVLDKNDMVQLLGPRPFTEKSTYEEFVEGTGSLDEDTSLPEGLQDWNKEREKEEKKEKEKEEPLNEKVVS
What is the function of this protein?
ATP-dependent protease which is essential for axonal and neuron development (PubMed:18337413, PubMed:27642048).  In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (By similarity).  Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form.  Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP) (By similarity).  Involved in the regulation of OMA1-dependent processing of OPA1 (By similarity).  Contributes to the proteolytic degradation of GHITM upon hyperpolarization of mitochondria (By similarity).  Progressive GHITM degradation upon persistent hyperpolarization leads to respiratory complex I degradation and broad reshaping of the mitochondrial proteome by AFG3L2 (By similarity).
What are the official names of this protein?
AFG3-like protein 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURI_STRA3
Sequence: MDSRPIGFLDSGVGGLTVVKEMFRQLPEEEVIFIGDQARAPYGPRPAQQIREFTWQMVNFLLTKNVKMIVIACNTATAVAWQEIKEKLDIPVLGVILPGASAAIKSTNSGKVGIIGTPMTVKSDAYRQKIQALSPNTAVVSLACPKFVPIVESNQMSSSLAKKVVYETLSPLVGKLDTLILGCTHYPLLRPIIQNVMGAEVKLIDSGAETVRDISVLLNYFEINHNWQNKHGGHHFYTTASPKGFKEIAEQWLSQEINVERIVL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: U7B_CONDE
Sequence: DCIPGGENCDVFRPYRCCSGYCILLLCA
What is the function of this protein?
May inhibit sodium (Nav) or calcium channels (Cav).
What are the official names of this protein?
Conotoxin de7b.
What are the subcellular locations of this protein?
Secreted.
Protein: RNP2_THEKO
Sequence: MREKPKYLPPTLRDKNRYIAFQVIGERPFKKDEIKKAVWEASLSALGYLGSARAKPWFIKFDEKSQTGIVRVDRKHVEELRFALTMLTEINGSKVIFRTLGVSGTIKRLKRKFLAEYGWR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_NOCSJ
Sequence: MAIEGSANMIGYGLAAIGPGVGIGLIFAAYISGVARQPEAQSRLQAIAILGFALAEALAIIGIALAFVL
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MED19_ASHGO
Sequence: MGTVHDDATMPSYYYYVDPAGPAYEPQQPNPIDDLISVYGLQDISRQVARTNADGTKAVKLRKSYKNQIQDLSGKFSVIPTRENGKGGEISPIVFQNTDGDAVRERGMGPEEWRRAQVFRDQALFEAPTMDWDMCAEVISQFERSYPGEFKNQGFEVEDLAFDLDGSGANGAALGGKAKKRKSRSNGSSMATPNSDLQEDIKRRRLE
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 19, Mediator complex subunit 19.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPE_BACCR
Sequence: MKTFPVSIVTPDGPVYEKEVEMVSVKAESGEMGILPGHIPTVAPLKISAVRLKNGGHTDYVAVSGGFIEVRPDKVTVLSSSAEEANHIDIHRANEAKRRAEQRLQDKQAHVDFKRAEMALQRAVNRLNVSDMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y4121_ARATH
Sequence: MFRFNFRREISKYTGIYHRKIHSGLEDAGPMASRLKSRSVVRFSGPDTVKFLQGLLTNDVRRFGESSGEKNSAVPTPNMASVTNPPMYAALLTPQGRFLYDFFLYSPSRPDEKLDRTGSGPGSDSGRDGSVELFADVDVDVLDELLETLKKYRLRSKVDIENVAEEFSCWQRYGRNLTGSSSVGWGGGVDRAGESTASGNKYGWQWYKDPRLECLGYRSIFPSDATPPLVEADKETDESNYLLWRLEHGVAEGSAEIPKGEAIPLEYNFVGLNAISFDKGCYVGQELIARTHHRGVIRKRLIPLRFIDSNGKELNQKIAAGAEVVESGTGKKMGTVSTALGSRGMGVMRVEEAFKPSAELAVKDSEEVKVEAIKPTWWPAEWFQQNQSGVAAA
What is the function of this protein?
Folate-dependent protein involved in Fe/S cluster biogenesis.  Functionally complements an E. coli mutant defective in ygfZ.
What are the official names of this protein?
Putative transferase At4g12130, mitochondrial, Iron-sulfur cluster assembly factor homolog COG0354.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ETV5_MOUSE
Sequence: MDGFCDQQVPFMVPGKSRSEDCRGRPLIDRKRKFVDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGAKYGEKCLYNYCAYDRKPPSGFKPLTPPATPLSPTHQNSLFPPPQATLPTSGLTPGAGPVQGVGPAPTPHSLPEPGSQQQTFAVPRPPHQPLQMPKMMPESQYPSEQRFQRQLSEPSHPFPPQSGVPGDSRPSYHRQMSEPIVPAAPPPLQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMGIKQEPRDYCADSEVPNCQSSYMRGGYFSSSHEGFPYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECPLNEEDTLPLTHFEDNPAYLLDMDRCSSLPYTEGFAY
What is the function of this protein?
Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA. -3'.
What are the official names of this protein?
ETS translocation variant 5.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LDH2_BACCR
Sequence: MKKGINRVVLVGTGAVGCSYAYSMINQGVAEEFVLVDVNEAKAEGEAMDLSHAVPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVRGIMDSGFDGIFLIATNPVDILTYVTWKESGLPKERVIGSGTTLDSARFRYMLGDYLDVDPRNVHAYIVGEHGDTELPVWSHATIGVQKLETILANNEQYKQEDLDKIFENVRDAAYQVIERKGATYYGIGMSLLRVTKAILNNENSVLTVSAYLEGQYGEKDAYVGVPAVINREGVREIVELELNEDEKAKFAHSVKVLKETMAPVL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 2, L-LDH 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_CLONN
Sequence: MGKPIVAIVGRPNVGKSTLFNKLAGKRIAIVDDMPGVTRDRIYAEAEWLNNNFTIIDTGGIEPENDDIIVAQMRRQAQLAIEMADVVLFIVDGKQGLTDADREVAHMLRKASKSIVLAVNKIDRRQLDDNIYEFYNLGLGDPMPISASQGLGLGDLLDEVIEKFPEGNVEEEEDEYIRIAMIGRPNVGKSSLINKILGEEKHIVSNIPGTTRDAVDSYVETEEGKFVLIDTAGLRRKSKIKEQVERYSAVRTLASIENADVCILMIDATEDIAEQDERIIGYAHEINKAILVIVNKWDLIEKDDKTMKNFKDKLRTKLSFLPYASFLFISAKTGQRVHKVLGMAKECYGNYCKRIKTGILNDIINKAVLMKEPPVMGTRRLKIYYVTQIGTKPPTFVFFVNDPELLHFSYRRYLENKLRESFDFSGTGIKLEFRERKE
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PBIR1_CHICK
Sequence: MAQEKMELDLELPPGSAAAPSDGGGLRRSNSAPLIHGLSDNSQVFQGSVLRTRRNSTTVMNRHSLFVPSSPIRIPSSRLHQIKQEEGMNLMNRETVHEREVQVAMQMSQSWEESLSLSNNDFEKSSSPKQVDFVPVSPAPSPTRGIGKQCFSPSLQSLVSSSGLPPSPSPSPTRRFSSRRSQSPINCIRPSVLGPIKRKGVTEMEDHPKRLFQGSTNMLSSEALHQPDLGGCLSAHTLDDNRSSAGSSCDSPAEAGASTGSPVSLSDSRSPFLPVDLTAKLPID
What is the function of this protein?
Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity.  Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA).  Inhibits PP2A-mediated dephosphorylation of WEE1, promoting ubiquitin-mediated proteolysis of WEE1, thereby releasing G2/M checkpoint.
What are the official names of this protein?
P2R1A-PPP2R2A-interacting phosphatase regulator 1, PABIR family member 1.
What is the protein family that this protein belongs to?
Belongs to the FAM122 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PAG55_CAPHI
Sequence: ISSPVSXLTIHPLRNIMDMLYVGXITI
What are the official names of this protein?
Pregnancy-associated glycoprotein 55, PAG 55.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: SYA_CAMJR
Sequence: MDIRKAYLDFFASKGHEITPSSPLVPDDATLLFTNAGMVPFKSIFTGEIPRPNPPRKTSCQTCIRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEQAIAYAWEFVTEVLKLPKDRLYVTVHENDDEAFNLWQKHIQKERIYKFGDKDNFWQMGDTGPCGPCSEIFYDQGQEHFNSSEDYMGGDGDRFLEIWNLVFMQYERSADGVLSPLPKPSIDTGMGLERVTAIKEGKFSNFDSSLFMPIINEISKLCNKTYVYESGASFRVIADHIRSSVFLLAQGVSFDKEGRGYVLRRILRRALRHGYLLGFKQAFMYKLVDIVCDLMGGHYTYLNEKKDFIKEQIRLEEERFLSTIENGIEIFNEELKNTKEIFSGEVAFKLYDTYGFPLDLTADMLREKNLKVDEEKFELFMNEQKARAKASWKGSGDKTASGDFKNLLEKFGENHFVGYEKAECESKILALLDEDFKEVSTLKDAGWVMLENTPFYATSGGQSADSGFIAKREVLDTQKFFNLNLSFIKAGEELKVNDIVHARIDTEKREQIARHHSATHLLHHALREILGSHVSQAGSLVESNKLRFDFTHHKALNKEELESIEKRVNKMIINSSEAILENMPLEEAKKSGAIALFNEKYQGNVRVLTLGESKELCGGTHVKNTAQIGSFYIVKESGVSAGVRRIEAVVSKAALEFVKNQLEELSKVKDELKNNDILSGIKKLKNEILSLKNELKNSSKTELDSKNIQGVEICVKRIDNGDIKAMIDDFKNKFAKAVILLIQVKDEKITLAAGVKDVPLKAGALVKEAAQILGGNGGGRDDFATAGGKDLSKINEALKQSLETIEKAL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLZH_BACSU
Sequence: MIIAFKIVFVNIFSLQHNAAIEVSLTAEYAMHTLKTKIRRKSFHLQMYHTFLNIARKAEKI
What are the official names of this protein?
Uncharacterized protein YlzH.
Protein: ARGC_PARD8
Sequence: MIKCGIIGGAGYTAGELIRLLLNHPDAELTFINSSSNAGNKITDVHGGLYGETDLVFTSELPLDSIDLLFFCTAHGDTKKFMENHTVPENVKIIDLSMDYRIEGPEHDFVYGLPELNRRRICNARHIANPGCFATCIQLGVLPLAKHLMLNSDLHVNAITGSTGAGVKPSSTSHFSWRNDNISIYKPFTHQHLAEINQSLSQLQKSYSSRINFIPVRGNFSRGIFATTYIDCKIDLVEIRRIYEEYYDDHSFTFITDKNPDLKQVVNTNKCLIHLQKIDDKLLIISMIDNLLKGASGQAVHNMNLLFGLEETVGLHLKPSAF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIK_ECO81
Sequence: MPFRSNNPLTRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGEVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRLLRLSPLHMDVHAGNLVHSAPGLKLIDWEYAGDGDIALELAAVWVENTDQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.
Protein: 92KD_BACCE
Sequence: AHPPEXLSIA
What are the official names of this protein?
92 kDa protein.
Protein: ARGB_SHESW
Sequence: MSTNNSVLVLKVGGALLQCEMGMARLMDTAAAMLANGQQVLMVHGGGCLVDEQLAANGMETVKLEGLRVTPPEQMPIIAGALAGTSNKILQGAATKAGIVSVGMSLADGNTVSAKIKDERLGLVGEVTPKDGTYLKFILEQGWMPICSSIAMMDDGQMLNVNADQAATALAKLVGGKLVLLSDVSGVLDGKGQLIHSLNGKQIADLVKQGVIEKGMKVKVEAALEVAQWMGQAVQVASWRDASQLIALAKGEAVGTQIQP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBO_VOLCA
Sequence: MRAAQTVKAAGVSRAARPVRANVVCKAQKVEFGQAAAAVVAASALVAGSANALTYDELQGLTYLQVKGTGIANTCPVLEKGSTDLSELSAGTYKLENFCIEPTSFTVKEESVFKGGETEFVKTKLMTRLTYTLDAMSGTLKVGSDGSAELKEEDGIDYAATTVQLPGGERVAFLFTIKQFDGKGTLDNIKGDFVVPSYRGSSFLDPKGRGGSTGYDNAVALPARADAEELLKENVKSTKALKGSAVFSVAKVNTATGEIAGVFESIQPSDTDLGAKPPKDIKITGLWYGQLSQ
What is the function of this protein?
Stabilizes the manganese cluster which is the primary site of water splitting.
What are the official names of this protein?
Oxygen-evolving enhancer protein 1, chloroplastic, OEE1.
What is the protein family that this protein belongs to?
Belongs to the PsbO family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: SSRP_MYCTA
Sequence: MSKSSRGGRQIVASNRKARHNYSIIEVFEAGVALQGTEVKSLREGQASLADSFATIDDGEVWLRNAHIPEYRHGSWTNHEPRRNRKLLLHRRQIDTLVGKIREGNFALVPLSLYFAEGKVKVELALARGKQARDKRQDMARRDAQREVLRELGRRAKGMT
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RNAS2_MACNE
Sequence: MVPKLFTSPICLLLLLGLMGVEGSLHAKPRQFTWAQWFEIQHINMTSGQCTNAMLVINNYQRRCKNQNTFLLTTFADVVHVCGNPSMPCPSNTSLNNCHHSGVQVPLIHCNLTTPSRRISNCRYTQTTANKYYIVACNNSDPVRDPPQYPVVPVHLDRVI
What is the function of this protein?
This is a non-secretory ribonuclease.  It is a pyrimidine specific nuclease with a slight preference for U.  Cytotoxin and helminthotoxin.  Possesses a wide variety of biological activities (By similarity).
What are the official names of this protein?
Non-secretory ribonuclease, Eosinophil-derived neurotoxin, RNase UpI-2, Ribonuclease 2, RNase 2, Ribonuclease US.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Lysosome. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Protein: SYDND_BRASO
Sequence: MHRYRTHTCGALRDSNIGETVRLSGWCHRIRDHGGVLFVDLRDHYGITQCVVDPDSKAFGLAEKLRSEWVVRMEGKVRHRPEGTENPELPTGQVELYVADIEVLGPAAELPLPVFGEQDYPEDIRLKYRFLDLRRDRLHQNIMTRGAIIDSMRRRMKEQGFFEFQTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDVEMSFVEQEDVFAAMEPVITGVFEDFAKGKPVTKGWPRIPFAEALRKYGTDKPDLRNPLEMQDVSEHFRGSGFKVFARMLEDPKNQVWAIPAPGGGSRAFCDRMNSWAQGEGQPGLGYIMWREGGEGAGPLANNIGPERTAAIRSQLGTKEGDAAFFVAGDPDKFWKFAGLARTKVGEELNLIDKDRFALAWIVDFPMYEYNEDDKKVDFSHNPFSMPQGGLEALTTKDPLTIKAFQYDIACNGYEIASGGIRNHKPEAMVKAFEIAGYGEQEVVDRFGGMYRAFQYGAPPHGGMAAGVDRIVMLLCGTTNLREISLFPMNQQAMDLLMGAPSEATTKQLRELHIKPNLPNK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDP_SALPA
Sequence: MDELTAQALKAFTTRYCDAWQEKHGSWPLSEELYGVPSPCIISSTRDAVYWQPQPFEGEENVNAVERAFDIMVQPALHAFYTTQFAGDMPAQFADEKLTLLQTWSQDDFRRVQENLIGHLVTQKRLKLPPTLFIATQENELEVISVCNLSGEVIKETLGTRNRTVLAATLAEFLTQLNPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: PRIB_PHOPR
Sequence: MTNRLELSGVIAKDPKRSQSPAGVPHCHFVLEHRSYQREADLPRQVYCYINVVSSGKGLQVLTQDLAVGVHTKVAGFISYQTGRNGIGKLVLHADHIEIICSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: RCEL_BLAVI
Sequence: MALLSFERKYRVRGGTLIGGDLFDFWVGPYFVGFFGVSAIFFIFLGVSLIGYAASQGPTWDPFAISINPPDLKYGLGAAPLLEGGFWQAITVCALGAFISWMLREVEISRKLGIGWHVPLAFCVPIFMFCVLQVFRPLLLGSWGHAFPYGILSHLDWVNNFGYQYLNWHYNPGHMSSVSFLFVNAMALGLHGGLILSVANPGDGDKVKTAEHENQYFRDVVGYSIGALSIHRLGLFLASNIFLTGAFGTIASGPFWTRGWPEWWGWWLDIPFWS
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein L chain, Photosynthetic reaction center L subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Multi-pass membrane protein.
Protein: ACTG_RAT
Sequence: MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, cytoplasmic 2, Gamma-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CORZ_KARBI
Sequence: QTFHYSQGWTN
What is the function of this protein?
Cardioactive peptide.  Corazonin is probably involved in the physiological regulation of the heart beat (By similarity).
What are the official names of this protein?
Corazonin.
What is the protein family that this protein belongs to?
Belongs to the corazonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: COXX_EHRCR
Sequence: MSSKCESVKPQLVNEVLGYWDLLKPKIMYLVVLTGITGMIIAPGNIHPFIGIISTLCIALGSGAAGAINMWYDSDIDALMQRTKNRPIPSGKIARSTAIELGLVLSVISVTVMMIAVNYLSGILLAISIGFYSLVYTMYLKRRTPQNIVIGGIAGALPPIIGWTSVTNAISIESLILFLIIFVWTPPHFWALSLLNYQEYEKAKVPMLPVTHGIFTTKIYILVYSIILFIITLLPGIFLKDCLLYETCAIPLGMTFVFHAFKVFVSINHYKYKAMFTYSIAYLFILFICIIISSF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.