PharMolix/UniProtQA huggingface dataset:
Protein: AT2B1_CHICK
Sequence: MGDMANNSVAYSGVKNAVKEANHGEFGVTLAELRSLMELRATDALHKIQECYGDVQGICTKLKTSPNEGLSGNPADIERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAVVSLGLSFYQPPGGNEALCGSVNVGEEEEESEAGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADIIVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDRDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGDEEEKEKEKKDKKTKAQDGAAMEMQPLKSEDGVDGDEKDKKRSNLPKKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTSWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMRDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYISEKHYKKIPAPEAIPENIMAYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGFLLDLKRDYQDVRNEIPEEKLHKVYTFNSVRKSMSTVLKNSDGSFRIFSKGASEIVLKKCFKILSADGEPKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIALKCGILNPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTIFDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTEALLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKIFDIDSGRNAPLHAPPSEHYTIVFNTFVMMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCSKLSIEQWLWSVFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPETRSSIHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSTPPPSPNKNNNAVDSGIHLTTDMNKSATSSSPGSPLHSLETSL
What is the function of this protein?
Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis.
What are the official names of this protein?
Plasma membrane calcium-transporting ATPase 1, Plasma membrane calcium ATPase isoform 1, PMCA1, Plasma membrane calcium pump isoform 1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MFD_SYNY3
Sequence: MAEPRAVLKQGNRNRDKDSVGLGNRLRFVSISSALNPMTFSSILRHLQTLPLSKDLREKLQKRGHVQLSGLPRLPKGLIVSSLAQSLEKNLLVITATLEEAGRWTAQLELMGWQTVNFYPTSEASPYDPGRLESEMVWGQMQVLAELIQGHQVKGKAIVATEKALQPHLPPVATLREYCLALRRGQEMDSKSLELTLARLGYERGSTVETEGQWSRRGDIVDIFPVSAELPVRLEWFGDELEKIREFDPASQRSLDDLTGLVLTPTSFDQVIEPALNAQAIDLSAWGEDAETEQLFGKEGLQRFLGLAFTEPACLLDYLPTETVCVLDEPEQCAAHSERWFEAVAQDWSALQLPNLPQLHRNFSALGDRLKTDFQYITLSEIHEANGDSLDISARPIPTMPHQFAKLAEILRGKREIYSGLTLGQYSTWLISAQPSRTVSLLQEHDCAVQFIANPRDYPAIEKSQIQRTAVTLKYSGLAELEGFILPTFRLVLVTDRELFGQHALATPEYVRKRRRATSKQVDINKLSPGDYVVHKSHGIGKFLKLDALANREYLMIQYADGILRVPADSLDSLSRFRHTGTRPPELHKMGGKVWEATKNKVRKAVKKLAVDLLNLYAKRAKQVGYAYPPDSPWQQELEDSFPYQPTPDQLKAVQDVKRDLEGDRPMDRLVCGDVGFGKTEVAVRAIFKAVTSGNKQVALLAPTTVLTQQHYHTLKERFAPYPITIGLLNRFRTASEKKEILAKLKSGELDIVVGTQQVLGTSVKFKDLGLLVIDEEQRFGVNQKEKIKTLKTEVDVLTLTATPIPRTLYMSLSGIREMSLITTPPPSRRPIKTHLSPYNPEVIRTAIRNELDRGGQVFYVVPRIEGIEELGGQLRQMVPSARIAIGHGQMEESELESTMLAFNDGEADILVCTTIIEAGLDIPRVNTIIVEDAQKFGLAQLYQLRGRVGRSGIQAHAWLLYPNQKQLTEKARLRLRALQEFSQLGSGYQLATRDMEIRGVGNLLGAEQSGQMEAIGYEFYMEMLQDAIKEIQGQEIPKVEDTQIDLPLTAFIPSDYIPDLEEKMAAYRRITSIESTDELPKIALDWGDRYGMLPSPVEELFKVVKLKHLAKSLGFSRIKVEGKQNLVLETPMEEPAWKLLAENLPNHLQSRFVYSAKKVVVRGLGVLAPAKQMDNLIDWFGKMQGALPETKMETLVGK
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_BEII9
Sequence: MARKHFGTDGIRGRANAAITPELAMKVAQATGVLFQRGEQRHRAVIGKDTRLSGYMIEYAMVAGFTSVGMDVLLLGPMPTPAVAMLTPSMRADVGVMISASHNPYEDNGIKLFGPDGFKLSDEMEAEIEAKLDRDVALKLSKPADLGRAKRVEGAQARYIEFTKRTLTRSLSLEGLRIVIDCANGAGYKVAPEALWELGAEVFAIGTEPDGFNINRDVGSTAPAALVKKVHEVRADIGIALDGDADRVIIVDENGKVIDGDQLMAAIAAGWQEEGRLARPGIVATLMSNLGLERYLESIGLTLARTAVGDRHVLEHMRAHGYNLGGEQSGHIILSDYCTTGDGLVAALQVLALVKRLGKPVSQVCRRFDPVPQILKNVRVNAAQSLEQDHVKRVIEEGHRKLGKNGRLVIRPSGTEPVVRVMGEGDNRDLVETIVDDICEALNAATPLAAE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RS14_HERAR
Sequence: MAKLALINREQKRADLVKKYAGKRAELKAIIDDHSKSEEERYEARLKLQALPRNSAPTRQRNRCALTGRPRGTFRKFGLGRIKLRECAMRGEIPGMTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RS13_FERNB
Sequence: MARIVGVEIPSNKKVHIALRYLYGIGPTRAMEICKNTGVDPDKRVKELTEDEISKIASFIQQNYKVEGELRTEVMRNIKRLMDIGCYRGLRHKLGLPVRGQRTRSNARTRKGPRPSRIKKKGK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: OBG_THESQ
Sequence: MNIERADFVDRVKIFVKAGDGGNGCVSFRREKYVPKGGPDGGDGGDGGFVFLRANPSVSTLIEFVNKRKFVAENGKHGMGKKMKGRNGKDLFIDVPVGTVVKDAVTGEIIADLNEPGKIVCVARGGKGGRGNAHFATSTKQAPLIAERGEKGESRWLELELKILADVGLVGYPNVGKSSLISRISNARPKIANYPFTTLIPNLGVVKYDDFSFVVADIPGLIEGASEGVGLGNVFLRHVERCYLIAHVIDVSGYEREDPVRDYFVIREEMKKYSPFLLEKPEIVVANKIDLIGKEELEKILKRLRDATNREVIPVSALTGEGIDLLVSKLASIVREMKVEKSERKEEKFVKPSPVWRRLPEKFHLEVVKEDEGYWVVEGENLRVWIERFDLNQRDARLMLLQVLEKNGLNNKLKEAGVKEGDVVRIGDFEFEYRE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_LIRMU
Sequence: KASVGFKAGVKDYRLTYYTPDYETKDTDILAAFRVTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEAVIGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEALYKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGAPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKGLRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREAAKWSPELA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CAPSD_BPLC2
Sequence: MKVKAVRGIANPLGTIDAHGTVIESIANAGDGVDILNRHREKIGSGFVHLEGDNVILTGYVDEEQYTAEKIEETGLSVGFNANGVKAREIDGVGYYKDVTITEVSLTPLPSNKGAKVTKVREENKGEQEQMGANETQEIMKQAIEAGVKVRELEAKVEELNKEREELKKEREASIPSEKPEDAERKFMRELGSKMAEMPEQGFLREFANGADLNVVNSLGSITSKYARKSGIYDGAMKARFQGLTLAEDGVDDTFISGTFKAGTDKNKSQTATKRSLRPQMAEAYLQMDKATVRGVNDSGALSEYVMSEMVNRVIQKVEYNMILGSVDGSNGFYGLKTATDGWTKQIEYTDLFEGITDAVAECSISDAITIVMSPQTFAELRKAKGTDGHSRFNELATKEQIAQSFGAVNLETRVWMPKDEVAVYNHDEYVLIGDLNVENYNDFDLRYNVEQWLSETLVGGSIRGKNRSAYLKKKGSLGV
What is the function of this protein?
Assembles to form a prolate capsid about 56 nm in length and 41 nm in width.
What are the official names of this protein?
Major capsid protein, Gene product 15, gp15, Major head protein.
What are the subcellular locations of this protein?
Virion.
Protein: RUVB_SALPK
Sequence: MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKRRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGAISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CA4E_CONPU
Sequence: DCCGVKLEMCHPCLCDNSCKNYGK
What is the function of this protein?
Probable neurotoxin with ion channel inhibitor activity (Probable).  In vivo, elicits dose-dependently excitatory activity upon injection into fish.  Its action is slowly reversible (PubMed:17118419).
What are the official names of this protein?
Conotoxin PIVE, Kappa-A-conotoxin PIVE, KappaA-PIVE.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: XTH18_ARATH
Sequence: MKLSCGTSFAFLIMFLFAAQSMHVYAGSFHKDVQIHWGDGRGKVRDRDGKLLSLSLDKSSGSGFQSNQEFLYGKAEVQMKLVPGNSAGTVTTFYLKSPGTTWDEIDFEFLGNLSGHPYTLHTNVYTKGSGDKEQQFHLWFDPTVNFHTYCITWNPQRIIFTVDGIPIREFKNSESIGVPFPTKQPMRLYASLWEAEHWATRGGLEKTDWSKAPFTAFYRNYNVEGCVWANGKSSCPANSSWFTQQLDSNGQTRMKGVQSKYMVYNYCNDKRRFPRGVPVECS
What is the function of this protein?
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).
What are the official names of this protein?
Probable xyloglucan endotransglucosylase/hydrolase protein 18, At-XTH18, XTH-18.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 2 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: BALDH_ANTMA
Sequence: MAAHRFSSLLSRSVPLLSRGGKQSYLGRGVYRYGTAAAAALEEPIKPPVSVQYDKLLINGQFVDAASGKTFPTLDPRSGEVIAHVAEGDAEDINRAVAAARKAFDEGPWPKMPAYERQKIMLRFADLVEKHNDEVAALEAWDSGKPYEQCAQVEIPMFVRLFRYYAGWADKIHGLTIPADGPHHVQTLHEPIGVAGQIIPWNFPLVMFGWKVGPALACGNSVVLKTAEQTPLSALLVSKLFHEAGLPEGVLNIVSGFGPTAGAALCRHMDVDKLAFTGSTETGKIVLELSAKSNLKPVTLELGGKSPFIVCEDADVDKAVELAHFALFFNQGQCCCAGSRTFVHEKVYDEFVEKAKARALKRTVGDPFKAGMEQGPQVDADQFEKILKYIRSGAESGATLETGGDRLGTKGYYIQPTVFSDVKDDMLIAKDEIFGPVQTILKFKELDEVIRRANNSSYGLAAGVFTQNLDTANTMMRALRAGTVWINCFDTFDAAIPFGGYKMSGIGREKGEYSLKNYLQVKAVVTALKNPAWL
What is the function of this protein?
Component of the floral volatile benzenoid/phenylpropanoid (FVBP) biosynthetic pathway (PubMed:19292760).  Catalyzes the oxidation of benzaldehyde to benzoic acid (BA) (PubMed:19292760).  Capable of oxidizing a broad spectrum of aliphatic aldehydes; increased carbon chain length results in a decrease in its efficiency (PubMed:19292760).
What are the official names of this protein?
Benzaldehyde dehydrogenase, mitochondrial, 2-phenylacetaldehyde dehydrogenase, Acetaldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL32_SHEB2
Sequence: MAVQQNKKSRSKRGMRRSHDALSTAQLSVDATSGEIHMRHNVTADGFYRGKKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ALR_HELPY
Sequence: MLKRASFVEVDTASLRHNFSAVKSIVPKDACVMAVVKANAYGAGAIKASEIFLQEGANYLGVATLDEALELRSHFSKTPILILGYSPNANASMLVDNDLSAMIFSLEQAEVFSQMALKSQKRLKVHIKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIEGIFTHLSNADAKIKTHAKNQMKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMKESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMDQCFVKLNNIQAKEGDEVILFGDKSAKANDASEIXALLNTIAYETISTLSKRLERVYI
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: DCUP_CAMJE
Sequence: MIFIDACFKKPTPYTPIWMMRQAGRYLPEYMEVRKQAGDFLSLCKDYKKASEVSLQPIDILDVDAAIIFSDILVVPLEMGMNLRFEKGEGPVFGNPISTLEDLEKLDDQNAHKKLNYVYDALKLTREKLSQNKALIGFCGSPWTIATYMIEGSGSKNYAKCKKMLYQNPELLHKILNKLTQVLKLYLEEQIKAGANAIQIFDSWASALEYDKFFEFSFNYMLEISNFIKSKYPNIPVILFPKGISGYLDRIDGNFDVFGVDWSTPLDLARDKLSHKYTLQGNMEPCRLYDKNAIKEGVEKILKTMQNKAHIFNLGHGILPDIPVENAKYFIKLVQESSAK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_RALSO
Sequence: MNAPHPASAALTQTLAARPTLAELEARDAFAERHIGPSPDEQAAMLATLGYASRAALIDAVIPPAIRRQDGMPLGEFTQPLTEEAALAKLRGIAGQNRVVRSLIGQGYYGTHTPGVILRNILENPAWYTAYTPYQPEISQGRLEAMLNFQQMVMDLTAMDIANASMLDEATAAAEAMTLLQRVGKHPSNVFFVADDVLPQTLDVVRTRAEPIGVQVVTGPAADAAKHNAFGVLLQYPGTGGALLGGLSTYQALTDAVHAAGGLVVAAADLLALTLLAAPGEWGADVVIGNTQRFGVPFGFGGPHAGYMAVRDAFKRSMPGRLVGVTVDAQGNPAYRLALQTREQHIRREKATSNICTAQVLLGVMASMYAVYHGPQGLKRIAQRVHRLTATLAAGLRQIGYTLEAGAFFDTLTVATGPRTANLHIAAQAHGFNLRQIDDGRLGVSLDETVTRAEVVALWEIFAHAAHAGAPDFDQVEAGIADAFPASLARQSAYLTHPVFNAHHSEHEMLRYLRSLADKDLALDRTMIPLGSCTMKLNATAEMLPVTWPEFANIHPFAPADQTVGYREMIDQLEQMLCAATGYAAVSLQPNAGSQGEYAGLLIIHAYHASRGESHRDVCLIPSSAHGTNPASAQMAGMKVVVVACDERGNVDLADLEKKAAEHSANLAAIMITYPSTHGVFEEGVKRVCEIVHSHGGQVYVDGANMNAMVGTAAPGHFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVGAHLAPFLPGRAASGEDASQNIGAVSAAPFGSASILPISWMYIAMMGAAGLTAATEAAILSANYVARRLSPYYPVLYTGAHGLVAHECILDIRPLQKESGISNEDIAKRLMDFGFHAPTMSFPVPGTLMIEPTESEPKVELDRFIDAMIAIRGEVDQVISGAFDREDNPLKHAPHTAQVVMADDWSHRYTREQAAYPVASLRTRKYWPPVGRADNVYGDRNLFCACVPMSEYAQD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: BET3_YEAST
Sequence: MVSTTQSRSLKAMGEEIWKNKTEKINTELFTLTYGSIVAQLCQDYERDFNKVNDHLYSMGYNIGCRLIEDFLARTALPRCENLVKTSEVLSKCAFKIFLNITPNITNWSHNKDTFSLILDENPLADFVELPMDAMKSLWYSNILCGVLKGSLEMVQLDCDVWFVSDILRGDSQTEIKVKLNRILKDEIPIGED
What is the function of this protein?
Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1.  TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.  TRAPP II plays a role in intra-Golgi transport.  TRAPP III plays a role in autophagosome formation.  Required for sporulation.  Has a role late in meiosis following DNA replication.
What are the official names of this protein?
Trafficking protein particle complex subunit BET3, TRAPP subunit BET3, Transport protein particle 22 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum. Preautophagosomal structure.
Protein: COAA_MYCLE
Sequence: MPRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPGRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHTRVDLVTTDGFLYPNAELGRRNLMHRKGFPESYNRRALMRFVTSVKSGADYACAPVYSHLRYDTIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIQDIEQWYVSRFLAMRGTAFADPESHFHHYSALTDSKAIIAAREIWRSINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_ALIFM
Sequence: MAKLHDYYKSSVVAELTKEFSYTSVMQVPRVEKITLNMGVGEAINDKKLLENAAADMAIISGQKPLITKARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLISIALPRVRDFRGVSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTSANTDAEGRALLAAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GBB1_BOVIN
Sequence: MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Transducin beta chain 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
Protein: CADH5_BOVIN
Sequence: MQALVMLLATGATYYLGLLAAAAAAVNPGRPNTPGSLPAHRRQKRDWIWNQMHIDEERNDSLPHYVGKIKSSVDPKKTEYQLRGESAGKVFRVDKNTGDVYALERLDREKISEYHLTALVVDKDSKKNLESPSSFTIKVHDVNDNWPVFTHRVFNASVPEMSGIGTSVIQVTAMDADDPTVADHASVVYQLTKGKENFDIRGSGLIVTMNKHLDRETQDKYEVVVKAEDAQGRRGESGTATVFITLQDVNDNFPIFTQNRYTFSVPEDIRVGSPLGSLFVEDPDEPQNRKTKYSFVQGEYRDTFTIDTDPSHNEGIIKPIKPLDYERIRQYSFTIEATDPTIDLRYLGSTSPKNIARVIINVTDVDEPPIFQQPFYHFQLQENQKKPLIGSVLAKDPDAAQRDIRYSIRRTSDKGQFFGITKKGGIYNDKELDREVYPWYNLTVEAKEVDLSGTPTGKESIVQVHIEVMDENDNAPEFAKPYEPKVCENAPQGKLVVQISATDKDITPRDVKFKFSLSTEDSNFTLIDNHDNTANIIVKYGYFDRERAKVHHLPVLISDNGRPSLTGTSTLHVTVCKCNEHGEFTLCEEAAAQVGISIQALVAIFLCILTFTVITLLIILRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVLNSARHGGAKPPRPALDARPSLYAQVQKPPRQAPGAHAPGEMAAMIGVKKDEADHDGGGPPYDTLHIYGYEGAESIAESLSSLGTDSSDSDIDYDFLNDWGTRFKMLAELYGSDPQEELVY
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins (By similarity).  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity).  This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity).  It associates with alpha-catenin forming a link to the cytoskeleton (By similarity).  Acts in concert with KRIT1 and PALS1 to establish and maintain correct endothelial cell polarity and vascular lumen (By similarity).  These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B (By similarity).  Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction (By similarity).
What are the official names of this protein?
Cadherin-5, Vascular endothelial cadherin, VE-cadherin.
What are the subcellular locations of this protein?
Cell junction. Cell membrane; Single-pass type I membrane protein. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions.
Protein: RS1_PROSP
Sequence: ETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTTHLEGKELEFKVIKLDQKRNNVVVSRRAVIESESSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPEGTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLDIDEERRRISLGLKQCKSNPWQQFAETHNKGDRVEGKIKSITDFGIFIGLEGGIDGLVHLSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNYLAATKKGAIVTGKVTAVDAKGATVELTLGVEGYLRASEA
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: TAG52_CAEEL
Sequence: MNAGKEFNYYTYQSDSSQGSLQKAPDENTDYFTHKMNSYLPFDMSTLYANQPTEKIQILQEIYDTERTYVKALTIVDEIFIQQLNLWCPKSKKCFRSMFGEISAICKTHQILLESLQCKPIAEVFTKFVPFLKLYTSYASHYPNSLKIFAKLMSRNDFRKALTKIEEDPRVDGKKLQTYLIMPIQRIPRYIMLIQNLMNYSTEKDDMTNLYKALSGMQGLSDQIQSCMTAYENGERLLQIQLNFGLDGHILEPGRVLLKEGMLYKRELNGSANYQETVVFLFNDILLYGIKRISVMPLCKYEPSAILSLRHCIVQLDDIGGSIFIRCGDVGVDFTAYSLGGVTEWYNEICDAIDNAKKLRDTLRKESFKQKSLIFDKGFWQRNRDKLRNMITADMTGNISRVLTRKKPAPKLEESDFLRGQWTTSTIASNQRKRKVATLEDEEEDVFNMLSSPNLSQRKRKATLQENTPSGVGWTASPRSSSFRKRRASTLRNKNADVTDGNNYLSHLVLNDVTMTQPYTGLNAFVGTPKSRTPTDDDYDSDRDYVWTDDEEFVSDDKKIPIRRVASYDEEDRRPRDFSEVRRSVASEPPRRHLAVDDIRKLSYQQRSLEPFNMVTEDDDEDDIIDIKVKGERPRPWWETESAPPAIKNQKSSIIDSIRNSCAIM
What are the official names of this protein?
Putative protein tag-52.