PharMolix/UniProtQA huggingface dataset:
Protein: YIDC_BURM1
Sequence: MDIKRTVLWVIFFMSAVMLYDNWQRSHGRPSMFFPSATQTAPAAAGGASGAGATTTAGNVPAPAAGTAPATTAPAAQAQLVKFSTDVYDGEIDTRGGTLAKLTLKKQGDGKQPDLYITLFDHTAGHTYLARTGLLGGDFPNHNDVYTQVNAGPTSLSGDQNTLKLSFESPVKGGVKVVKTYTFTRGSYVIGVDTKIDNVGTTPVTPTLYMELVRDNTAVETPMFSHTFLGPAVYTDAKHFQKINFSDLDKNKADYVTSADNGWVAMVQHYFASAWIPQHGVKRDIYAEKIDPSLYRVGVKQPVAAIAPGQSADVQARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHSYVGNWGWAIVLLTLLIKAVFFPLSAASYKSMARMKEITPRMQALRERFKNDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWILWIHDLSQRDPYFILPVLMAVSMYVQTSLNPTPPDPVQAKMMKFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRKLGGVKKKPA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: H1613_CYRHA
Sequence: MNTVRVTFLLVFVLAVSLGQADKDENRMEMQEKTEQGKSYLDFAENLLLQKLEELVAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1a, U11-TRTX-Hhn1a, Hainantoxin-XVI.13, HNTX-XVI.13, Peptide F4-19.87.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RDRP_BSMV
Sequence: MDVVKKFAVMSVTVVAGPVLTLSSPVVVTFGTSLIAVSLVKRLLQEQPRVIAHDHEHYPGGSESSSSSCATAPILRNLSRDQCDSENIGCSSSACSPSEIVKVTRQVVEVERGLYRDKQQFGMDVVKKFAVMSVTVVAGPVLTLSSPVVVTFGTSLIAVSLVKRLLQEQPRVIAHDHEHYPGGSESSSSSCATAPILRNLSRDQCDSENIGCSSSACSPSEIVKVTRQVVEVERGLYRDIFQDNEIPSVMEEKLQKLLYSEGEKIRRRCQFEASTMHSRKVKVPEVGTIPDIQTWFDATFPGNSVRFSDFDGYTVATEDINMDVQDCRLKFGKTFRPYEFKESLKPVLRTAMPEKRQGSLIESVLAFRKRNLAAPRLQGALNEWHTIENVLKKALKVFFFEDLIDRTDHCTYESALRWWDKQSVTARAQLVADQRRLCDVDFTTYNFMIKNDVKPKLDLTPQVEYAALQTVVYPDKIVNAFFGPIIKEINERIIRALRPHVVFNSRMTADELNETVAFLTPHKYRALEIDFSKFDKSKTGLHIKAVIGLYKLFGLDGLLKVLWEKSQYQTYVKDRNFGLEAYLLYQQKSGNCDTYGSNTWSAALALLDCLPLEDAHFCVFGGDDSLILFDQGYIISDPCRQLAGTWNLECKVFDFKYPAFCGKFLLCIDGKYQFVPDAAKFITKLGRTDVRDVEVLSEIYISINDNYKSYKDFKVLDALDKALVDRYRSPYSAISALVSLCYHIFDFNKFKLLFNCEGKFVDKKLRKDFEW
What is the function of this protein?
RNA-directed RNA polymerase plays an essential role in the virus replication.
What are the official names of this protein?
RNA-directed RNA polymerase, Gamma-A protein.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Host chloroplast envelope. Note=The viral replication sites are located at the host chloroplast membrane.
Protein: QUEA_SALPB
Sequence: MRVTDFSFELPESLIAHYPQPERSRCRLLSLEGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGTELLLGDDESIHATMTARHGALFEVEFNDPRPVLDILNAIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLAALREKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQEVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKSDLIEPFFGDTQIFIYPGYQYKVIDALITNFHLPESTLIMLVSAFAGYQHTMNAYKTAVEQKYRFFSYGDAMFITYNPQAISERP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_BACFN
Sequence: MNPTERITTPHKTGEAKVIIFSAPSGSGKSTIINYLLAQKLNLAFSISATSRPPRGNEKHGVEYFFLSPDEFRQRIANNEFLEYEEVYTDRFYGTLKAQVEKQLAAGQNVVFDVDVVGGCNIKKYYGERALSLFIQPPCIDELRRRLIGRGTDTPEVIESRIAKAEYELSFAPKFDKVIINDDLETAKAHALKVIKEFLGIDTE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MALR1_HUMAN
Sequence: MLFFLDRMLAFPMNETFCCLWIACVFNSTLAQQGTESFQCDNGVSLPPDSICDFTDQCGDSSDERHCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVDSISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAERELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRVRLYNNKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFIALDHLWVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPVLTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIAEAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRPPKDHTLGNENGHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQILIKTEKGLSKVWQESKQNPGNHWQKADILLGKLRNFEVIFQGIRTRDLGGGAAIDDIEFKNCTTVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCSECPLNYCRNGGTCVVEKNGPMCRCRQGWKGNRCHIKFNPPATDFTYAQNNTWTLLGIGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTESSVYSFSNPLYGTTSGSLETLSHHLK
What is the function of this protein?
Enhances production and/or transport of FGF19 and thus has a role in regulation of bile acid synthesis.
What are the official names of this protein?
MAM and LDL-receptor class A domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein.
Protein: IF3_CHLP8
Sequence: MRKKRTAPQKSKPSYRVNEQIRVPEVRVVLPEGGMQIMKTQDARRLAQDRNLDLIEVQPNAQPPVCKLENYGKLIYKMDKKDKDLKKKQKTTSLKELRFHPNTDKHDFDFKTAHLEEFLRKGNRVRATIVFLGRSIIYKDKGFELANRLTERLSTVANRDGEPKFEGKKLFVYFEPDKKKIEQFEKQRAMAEKIASLPPLPPDNSGEPEDDE
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRPR_MAIZE
Sequence: XXGAAAKG
What is the function of this protein?
Promotes expansion of husk leaf blades.
What are the official names of this protein?
Husk leaf blades expansion-promoting protein.
Protein: TRMFO_DESAP
Sequence: MSGGVIVVGAGLAGAEASWQLVRRGVPVVLYEMRPRKCTPAHKTGDFAELVCSNSLRAEALTNAVGLLKEEMRRLGSLIMACADAHRVPAGGALAVDRQLFAAAVTERLTSHRLVTVCREEITTIPTAELVILATGPLTSDALADELRRLTGQEHLYFFDAVAPIVTLESIDQDRVFRSSRYGRGDPAYLNCPMSREEYERFWEALVAAERATRHTFERETHFEGCLPVEVIAARGRETLLYGPLKPVGLVDPRTGERPYAVVQLRQDNRAGTLYNLVGFQTNLKWGEQRRVFSMIPGLEQAEFVRYGVMHRNTYINAPVLLSPNLMLKSRPGLFIAGQLSGVEGYVESAAAGLVAGLNAARLYKGLEPLVFPPETAHGALINYIVTADPANFQPMNVNFGLFPPLPGKRVRRRPERNLAHAQRALERLAAWLTEKGEG
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GVPF_HALMT
Sequence: MSDNLYTYGVIEQEDIELEIDGVAGAERVYTVDYRTLSAVVSDIDTTDPERTDEDVQVHNTVLQHVLEYDGGRTVVPMSFGMAFKNGRTLKGVMRGARRALRSALNDIEGTVELGVKIITSSEGGVSHDAIRADIGDRLSELSINETENDLFSDRLVVNKSYLVARDRRDDFDAAIDTIEEEYGDELTVQYTGPWAPYNFVDIHIGADQQRGR
What is the function of this protein?
May play a structural or regulatory role in gas vesicle synthesis.
What are the official names of this protein?
Protein GvpF.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: CRCB_GLUOX
Sequence: MSFTTCLIVMVGGALGTLARYLVSVAAMPISRFIPWGTILPINALGSFVIGFFGTLTLADGRYPVSENMRLFVMIGLCGGYTTFSSFSLQTLDLIRNDAWGRASVNVAASVILCIGAVALGHITADGFNTGAIRIAQTATEEDA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SINE1_ARATH
Sequence: MGLNLNPILRQELANLDKDTESRKSAMKALKSYVKDLDSKAIPGFLAQVFETKETNSLSGEYTISLYEILARVHGPNIVPQIDTIMSTIVKTLASSAGSFPLQQACSKVIPAIARYGIDPTTTEDKKRVIIHSLCKPLTDSLLASQESLTSGAALCLKALVDSDNWRFASDEMVNRVCQNVVVALDSNSNQTHLQMGLVMSLAKHNPLIVEAYARLLIHTGLRILGFGVSEGNSQKRLSAVQMLNFLMKCLDPRSIYSEVELIIKEMERCQSDQMAYVRGAAYEAMMTSKRIAAELESKMEKGCRSVTGSNFSRRNCSSIVPDYSLSPESQTLGSFSGYDSPVESSPISHTSCNSEFDRRSVNRKLWRRDENGGVVDISLKDGLFSRVTKGSTTVSDSPLVPYDTCENGDEFEGFLMESLRNTTPSPQRQRSRRINAEDFNIFSTPRKLISSLQYPDDVDLDHSDIQSPILRGEREKTIGSRKNPKLRKQFPTMVETMSSTITVSEDTAQTQMITGKKKKKKMSYAKLVIAISFVVVALFATVILMVNQDDDVGYYTVPT
What is the function of this protein?
Plays a role in nucleus positioning in guard cells.
What are the official names of this protein?
Protein SINE1.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein.
Protein: NUOK_ACIBT
Sequence: MGQIPLEHGLIVATILFALGFYGVMVRRNLLFMLMSLEIMMNAAALAFVLAGSVWAQPDGQVMFILILTLAAAEACIGLAIVLQFYHRFHHLDVDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: F168B_BOVIN
Sequence: MNPVYSPGSSGVPYANAKGIGYPAGFPMGYAAAAPAYSPNMYPGANPTFQAGYTSGTPYKVSCSPTSGAVPPYSSSPNPYQTAVYPVRSAYPQQSPYAQQGTYYTQPLYAAPPHVIHHTTVVQPNGMPATVYPAPLPPPRGNGVTMGMVAGTTMAMSAGTLLTAHSPTPVAPHPVTVPTYRAPGTPTYSYVPPQW
What is the function of this protein?
Inhibitor of neuronal axonal outgrowth.  Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2.  Positive regulator of CDC27.
What are the official names of this protein?
Myelin-associated neurite-outgrowth inhibitor, Mani.
What is the protein family that this protein belongs to?
Belongs to the FAM168 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell membrane; Multi-pass membrane protein. Cell projection, axon. Note=Expressed in neuronal cell bodies and axonal fibers.
Protein: LEPA_AGARV
Sequence: MSIDQSKIRNFCIIAHIDHGKSTLADRIIEKTGTLTSREMQAQVLDNMDLERERGITIKSQAVRIIYTAKDGEEYIFNLIDTPGHVDFNYEVSRSLAACDGAILVVDAAQGVEAQTLANVYLALDHDLDVFPVINKVDLPSARPDEVAQEIEDVIGIEAMDAPRISAKTGLNIEDVLEQIVKKIPAPTGDKDAPLKALIFDATYDSYKGVIIFCRLREGSVKVGDTIKMMATGASDVVTEVGYFGAGQFIPCDELSAGMVGYIAASIKNVRDTRVGDTVTLVDRPCDEALPGYKKVNPMVYCGLYPADSAKYPDLRDALEKLQVNDASLQFEPETSLALGFGFRCGFLGLLHLEIIQERLEREFDLDLVTTAPSVIYKIHKTSGEVIDLTNPSNMPDPSEIEYMEEPYVSAEIMVTSDYVGAIMKLCQERRGVYISMEYIEKTRALIKYDLPLNEIIYDFFDALKSRSRGYASFDYEMKDYERSELVKLDILINKEMVDALSFIVFKESAYERGRKMCEKLKGEIPRHLFEIPIQAAVGGKIIARETVKALRKDVLAKCYGGDISRKKKLLEKQKEGKKRMRQVGNVEIPQEAFMSVLKLDEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ASTE_PARXL
Sequence: MPVSLLDDFLAYTLAGTRPAASEAQGTCAGGVRWSWLDDGVLLMEPAVQEEGMRSVLVSAGVHGDETAPIELLAFLVRDIAHGTAALTGRLLVILGNVDAMRDACRYRDDDLNRLFSGRHLQLPQSHEAPRAAALERAATRFFAAAPDNPGARWHIDMHTAIRASAFEQFALLPHTGKPFSRAMFEWLGEARISAVLLHTTRGNTYSHFTAQACGALACTLELGKVRPFGQNDLTRFAGADHAVRHLLAGMRGEVRAPMPRAFTVIDQITRQSEAFELLVAPDVANFTPFAKDTVLARDGDYRYVVRHDEERLVFPNATVKPGLRAGLMVIETTQDTLSKLV
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: LHA1_RHOPA
Sequence: MNQARIWTVVKPTVGLPLLLGSVTVIAILVHFAVLSHTTWFSKYWNGKAAAIESSVNVG
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-800-850 alpha chain A, Antenna pigment protein alpha chain A, LH II-A alpha.
What is the protein family that this protein belongs to?
Belongs to the antenna complex alpha subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: PURT_ECOL5
Sequence: MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAEELQLPTSTYRFADSENLFREAVAAIGYPCIVKPVMSSSGKGQTFIRSAEQLAHAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQNVTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: Y992_IGNH4
Sequence: MLVRPPAVAGTFYPADAEELIRLIEWSFTHPLGPGEVPEVSPVRRKASVGYMVPHAGYIYSGPVAAWSYYHLAQEGAPETVVIIGPNHTGLGPAVSVMPPSIWETPLGGVKTDDEAISELLKVSNVVEEDYSAHAYEHSLEVQLPFLQYLFGDSFRIVPIVMKVQTPSVARLLMQSIKEAMENLGRDYVVLSSSDLNHYEPHDITVEKDMLALEKIVNLDPEGLQEVLVKYDISMCGPGPVMVNMYLDKEYGAERAILLKHATSGDTSGDKSAVVGYAAVKFPLP
What are the official names of this protein?
MEMO1 family protein Igni_0992.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: THIQ_YERPN
Sequence: MLKLEKITYLYDHLPMCFDLRIQPGERVAILGPSGAGKSTLLSLIAGFLAPTGGHMLLNNQDHTASTPAQRPVSMLFQENNLFAHLTVEQNIGLGLHPGLKLSGEQRLLLQHIAQQVGLESCLDRLPAQLSGGQRQRAALARCLVRSQPILLLDEPFSALDPALRNEMLQLVDQVCINRQLTLLMVSHNLDDAARIAQRTLLIVEGRIDYDGPTQALVDGSAAKASVLGIKSAVIS
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HUTI_YERPG
Sequence: MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYEGGLITPGLIDCHTHLVFGDDRSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLLEQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARRLGELLPIDVKTTCLAAHALPPEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVKLHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMANAGTVAVLLPGAYYLLRETQCPPIDLFRQYKVPMALASDANPGTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGVQQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVFRGEVRP
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_COXBR
Sequence: MTESSFKLAIVVSQFNRAVTEKLLNGVLQRLTELGVQANQIKTVWVPGAVEIPLLAKRLAKSKHYQAVVCLGAVIRGETDHYNYVCQQVSFGCQQVALEYEVPIIFGVLTTTTKEQAFARAGGERGNKGADWADAAVSMIKLMKEIEITDE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: VASOT_HYBBI
Sequence: MKFALFSVLVVLLIATFVAADECPRICTADYRPVCGTPSGGRRSANRTFGNQCSLNAHNCLNKGDTYDKLHDGECK
What is the function of this protein?
Vasodilator protein that inhibits vasoconstriction of isolated rat femoral artery induced by phenylephrine.  Since platelet aggregation and vasoconstriction are key hemostatic responses, particularly in small wounds, this protein likely participates in the antihemostatic responses during blood feeding.  Blocks L-type calcium channels (Cav1/CACNA1) in left ventricular myocytes isolated from rat hearts.
What are the official names of this protein?
Vasotab.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVD_MYCLE
Sequence: MMPPDIKPRSRDVTDGLEKAAARGMLRAVGMNDDDFAKAQIGVASSWNEITPCNLSLDRLAKAVKEGVFSAGGYPLEFGTISVSDGISMGHQGMHFSLVSREVIADSVETVMQAERLDGSVLLAGCDKSLPGMLMAAARLDLASVFLYAGSILPGRTKLSDGTEHEVTLIDAFEAVGACSRGLMPRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAPPATDRRRDGFARRSGQAVIELLRRGITARDILTKEAFENAIAVVMAFGGSTNAILHLLAIAHEADVTLSLEDFSRIGFKVPHIADVKPFGRHVMFDVDHIGGVPVVMKALLDAGLLHGDCLTVTGQTMAENLASIAPPDPDGQVIRTLHNPIHPTGGITILRGSLAPDGAVVKTAGLDSDVFEGTARVFDGERAALDALKDGTIAKGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFSGGTTGFCVGHIAPEAVEAGPIAFLRDGDRVLLDVVGCSLDVLVDPVEFSSRKKDFIPPAPRYTTGVLAKYVKLVSSATVGAVCG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: IMA1_YEAST
Sequence: MDNGTDSSTSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFGFGSNVNQQFNFN
What is the function of this protein?
Functions in nuclear protein import as an adapter protein for importin beta nuclear receptors (PubMed:10913188).  Binds specifically and directly to substrates containing either a simple or bipartite NLS motif (PubMed:10745017).  Promotes docking of import substrates to the nuclear envelope (PubMed:8521485).  Together with importin beta KAP95, mediates nuclear import of transcription factor GCN4 (PubMed:14648200).  Together with tethering factor STS1, targets the proteasome to the nucleus (PubMed:10913188, PubMed:21075847).
What are the official names of this protein?
Importin subunit alpha, Karyopherin subunit alpha, Karyopherin-60, Serine-rich RNA polymerase I suppressor protein.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Note=Mainly localized at the periphery of the nucleus.