PharMolix/UniProtQA huggingface dataset:
Protein: RECA_AGGAC
Sequence: MATQEEKQKALDAALGQIEKQFGKGAIMKLGDSQKLDIEAISTGSFGLDLALGIGGLPMGRIVEIFGPESSGKTTLTLSVIAEAQKTGKTCAFIDAEHALDPIYASKLGVDVKEPLVSQPDNGEQALEICDALVRSGAVDVIIVDSVAALTPKAEIEGDMGDSHMGLQARLMSQALRKLTSQIKNANCLVIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRVGSIKEGDEVIGNETRVKVVKNKVAPPFRQVDFQILYGEGISKESELIELGVKHKLISKAGAWYAYQNEKIGQGKTNAMKWLKDNPEQAKFIESTLRDELLAHPESAITAEVEDEAGNGEGDFE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD8_XENLA
Sequence: MDATRKPLRIPPAMAVYAEEHGVFDIIQKMVEKVLVDRPEDPIQYMIDHLSNDNDDVPRVFILGPPASGKHTMAKLLCKRLNATHLTPENVLSSDVSLLVKEAQSYRDKGQEVPDELWAKLMRERLSQVDCIKRGWVLEGFPKTRDQALMLQMAGVCPGHLVVLDAPDIVLIERNMGKRIDITDGEVYHTTFDWPSDPAVQRNLVEPEGISEEETGQRLLEFHRNIPGLLRTYSKVSKKINVDQPYMDVFSQVLTFVLSKQRSLAPHTPRILLYGPPGSGRSLQASLLAQKYGIINICCGQVLKEAVADQTKLGELIQPYIENDQQVPDNFVLKILTDHLSSLESAKHGWVLHGFPQDTDQAALLKDAGFMPNRVFSLDLSDDVVIERLSLCMTDPVSGERYHSIYKPAPRSEVQERLQQNPKYSEEKVQARLDVYHANADELEEFYQDVIHINADQDPYTVFEFIESYIVSPLPKSLPEEPTSP
What is the function of this protein?
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.  Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP.  Also displays broad nucleoside diphosphate kinase activity.
What are the official names of this protein?
Adenylate kinase 8, AK 8, ATP-AMP transphosphorylase 8.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: OPPA_ECOLI
Sequence: MTNITKRSLVAAGVLAALMAGNVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPIELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH
What is the function of this protein?
This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.
What are the official names of this protein?
Periplasmic oligopeptide-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS8_ALBFT
Sequence: MSMSDPIADLLTRIRNAQMVAKTTVSVPSSKVKVAIAQVLTEEGYIDSFKVNANDGKPELEIVLKYYAGRPVIERIERVSRPGLRVYRGSDAIPQVQNGLGVAIVTTPKGVMTDRKARATGVGGEVLCYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GLYL2_HUMAN
Sequence: MLVLHNSQKLQILYKSLEKSIPESIKVYGAIFNIKDKNPFNMEVLVDAWPDYQIVITRPQKQEMKDDQDHYTNTYHIFTKAPDKLEEVLSYSNVISWEQTLQIQGCQEGLDEAIRKVATSKSVQVDYMKTILFIPELPKKHKTSSNDKMELFEVDDDNKEGNFSNMFLDASHAGLVNEHWAFGKNERSLKYIERCLQDFLGFGVLGPEGQLVSWIVMEQSCELRMGYTVPKYRHQGNMLQIGYHLEKYLSQKEIPFYFHVADNNEKSLQALNNLGFKICPCGWHQWKCTPKKYC
What is the function of this protein?
Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine (PubMed:22475485, PubMed:20305126).  Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0-CoA, to form a variety of N-acylglycines.  Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor.  Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine (PubMed:20305126).
What are the official names of this protein?
Glycine N-acyltransferase-like protein 2, Acyl-CoA:glycine N-acyltransferase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycine N-acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: RS12_SHESM
Sequence: MATVNQLVRKPRAPKVDKTNVPALNACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCAGVTSRRQSRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: Y4442_MYCA1
Sequence: MSEGRTDGDTWGPAQSVGATATMVAAARAVASQGPDALLDDPLAEPLVRAVGLDPFIRIVDGKLDFPDDPLFNRRARAEQITVRTRFFDDFFIDATEGGLRQAVILASGLDTRAYRLAWPAGTVVYEIDQPQVIAFKTDTLANLGAAPTAERRTISIDLRDDWPAALREGGFDVTRPTAWSAEGLLPYLPPEAQDRLFDNITALSAPGSRLATEHVPDPNAFSDERLARISERWQRLGLNLNAADLFYRGERNVVADYLTGKGWRVTPHPARQLYARNGFEFPEDEMRATFGEMSYVDATLTGGRG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4442.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: VERF_PENPO
Sequence: MSTEYPLVGSPETSEYPKYECSLCLKRYKRREHLFRHIGSHTSQRPYQCNSCDGAFQRADVLKRHLRTCDGGASRASTRRRACDRCVRQKKACSSHQPCHSCAKKGAQCLYSTDTGYSSRLSQHSSTNHTPKDQELSTQFTNPPPPPSTSTFNTMMPWGLTMEDLQNFGTSPTNTFFDPASMQYTSPTLPDFSVLPFEGPATFETPVSSDPPRKSLHFLDKFTSNTGLVSSFDCGTHEQREQIAARLDQQILSELQQRIMSMPALGMDIPSPLIMENNSDTSSTSDLPLDWFNDPLSLKTHEILLLVEEVVTIKPRNSSVALDWSSTLRDACLQFFSPSNIRRFLGFYWAIWHPNVNFVHRPTFDMLAAKPTLLAAMALIGACVSPDMPDNEDARTWFNCVEEMVFIDDDFNSDLTYQYSGNIAIQRRKIQAVQAAYIVCLYQNWEGADASKSRIRRYRFATLVSTARDIGITAARHLNYSELGRHEFEWKEYEAREELIRLFTWIFLLDSAFVIFNNLPPRMVIKEIRMHMATPEACFQATTADECHHQLHLFLPARTLYWTTSFRGSFESLCKDDLSVNIRHLLATLGPLNLFALTSAIHSQIFQFRSAVGSFQLRAPIQNALSNWRDIWQLFSSTFPQGITPHMTIEDPHIQPEELWKRMGFFRYAPEYWLLAHLMADRLAVLGTSKPENELEPLDEGPLDPILNRYDQTSMRQVNDLIMGFQTFQI
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of the neurotoxin verrucosidin, a methylated alpha-pyrone polyketide that inhibits oxidative phosphorylation in mitochondria and thereby causes neurological diseases.
What are the official names of this protein?
Transcription factor verF, Cluster 4 protein F, Verrucosidin biosynthesis cluster protein F.
What are the subcellular locations of this protein?
Nucleus.
Protein: XPOT_YEAST
Sequence: MLERIQQLVNAVNDPRSDVATKRQAIELLNGIKSSENALEIFISLVINENSNDLLKFYGLSTLIELMTEGVNANPNGLNLVKFEITKWLKFQVLGNKQTKLPDFLMNKISEVLTTLFMLMYSDCNGNQWNSFFDDLMSLFQVDSAISNTSPSTDGNILLGLEFFNKLCLMINSEIADQSFIRSKESQLKNNNIKDWMRDNDIMKLSNVWFQCLKLDEQIVSQCPGLINSTLDCIGSFISWIDINLIIDANNYYLQLIYKFLNLKETKISCYNCILAIISKKMKPMDKLAFLNMINLTNELTYYHQAISMNPQIITFDNLEVWESLTKLITSFGIEFTIIIEQVNDDQKLDTLYKQSVISNVDSILLEKIIPILLEFMNNEFDSITAKTFPFWSNYLAFLKKYKASSPNFVPLHKDFLDNFQQICFKRMKFSDDEVTQDDFEEFNETVRFKLKNFQEIIVVIDPSLFLNNISQEISANLMNCKNESWQIFELTIYQIFNLSECTKNNYFGLNKNEIMTSQPSLTLVRFLNELLMMKDFLLAIDNEQIQILFMELIVKNYNFIFSTSANTANATDDDEKYLLILNIFMSSFAMFNKRENVRLRSWYLFTRFLKLTRINLKKILFANKNLVNEITNKISPLLHIKVTSINAQGTDDNDTIFDNQLYIFEGIGFIITLNNSSQELTAATANTPIDYDILDQILTPLFTQLEGCITQGASPVVILECHHILMAIGTLARGLHIGLVPENQVNNMVVNKKLINDSLIHKFSNIAEVILVTFSFFNKFENIRDASRFTFARLIPILSNKILPFINKLIELILSSTDLKSWEMIDFLGFLSQLIHMFHTDTDCYQLFNQLLTPLINKVHSIIEEIDEQHDQQSSSNKPIDTAVTATSVNKNIVVTDSYRDKILLKKAYCTFLQSFTNNSVTSILLSDINRAILPVILNDLVTYTPQEIQETSMMKVSLNVLCNFIKCFGNGTCLDNDDINKDPNLKIDGLNEYFIMKCVPIIFEIPFNPIYKFNIKEGNFKTMAYDLARLLRELFIVSSNPTTNENECVKYLTQIYLPQIQLPQELTIQLVNMLTTMGQKQFEKWFVDNFISVLKQGQ
What is the function of this protein?
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.  Preferentially interacts with tRNAs with mature 5'- and 3'-termini and does not distinguish between intron-containing and spliced tRNAs.  In the nucleus binds to tRNA and to the Ran-GTPases GSP1 or GSP2 in their active GTP-bound form.  Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.  Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP cause release of the tRNA from the export receptor.  The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
What are the official names of this protein?
Exportin-T, Exportin(tRNA), Karyopherin-beta, tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm and the localization is regulated by SNF1 kinase, nutrient supply and stress.
Protein: DNAA_CLOAB
Sequence: MAAQLNELWQKTINIIKGELTEVSFNTWIKSITPISIDKDSIRLSVPNQFTKEILENRYKDLIINSMKIITTKKYDIAFLISSEEALETDEDQETDTNNVNTDTSSSMLNPKYKFDSFVIGNSNRFAHAACLAVAEAPAKAYNPLFIYGGVGLGKTHLMQAIGHYILDNNPKAKVVYVSSEKFTNELINSIKDDKNVEFRNKYRNVDVLLIDDVQFIAGKERTQEEFFHTFNALHENNKQIILSSDRPPKEIPTLEDRLRSRFEWGLIADIQAPDFETRIAILKKKADVEHLNIPNDVMVYIATQIKSNIRELEGALIRIVAFSSLTNKEISVDLASEALKDIISSKQNKQITIDLIQDVVSSYFNLRIEDFKSARRTKNIAFPRQIAMYLSRKLTDMSLPKIGEAFGGRDHTTVIHAYEKISSALKEDDDLKYTINEITKRFSPK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEK1_PSET1
Sequence: MPDTITNKLQNSTVQDVIATKLARAVFAGFEAMFATFLNITLGAQSRFEQRQYHEVQSAMRERLQVYERQVKSVSEAVKVIAYAELSCPQTWQLAKNIYGNMVKNHENEPIAHTFFNSTFGAIWDDKKIRTVHLFVLKAKYRTQPRPYDSLVKRISLQHGFNSAIKTLITNQVFRVPFSNLNQDVATLQATLTQGAKQQCRQVYELINLNDGYIEYAYSHFYRNKACYLIGRCIAKNGDNMPFAIAILNTPKGLKIDAVMMGADQLSLLFGFARTYFMVDTDQPARYVDYLSVLMPHKQRFELFNAIGFIKHAKTEFYRYKVDTTKNSPASFKYVAAPGTPGMVMLVFTIAGSDHVYKVIKDKFSAPKTATKAQVKEKYNFVKQADRVGRLVDTHEFRYLAFDLSRFSEQLLQQMKEHIGSSLIISGKALILKHVYVERKMTPLNLYINDCDSKALAQVMLDYGRAIKDLAGANIFPGDMLMKNFGVTRWGRVVFYDYDEICPLTDCNFREVPQTQNALEELSSDSYFDIEPNDIFPSQFKVFFSANELAFNAFNSHHSDLFNAQFWQTCQQQVQQGYLPDVYPYKQSWRFK
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase 1, IDH kinase/phosphatase 1, IDHK/P 1.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC58_MOUSE
Sequence: MEEAALGEAELNWSRLSVSAEALESELEARAEERRGAREALLRLLLPYNRLTSLPRALGGGFPHLQLLDVSGNSLTALGPELLTLSGLRTLLARNNRLGGPGSLPKGLAQSPLCRSLQVLNLSGNCFQELPASLLELRALQTLSLGGNQLQSIPAEIENLRSLECLYLGGNFIKEIPPELANLPSLNYLVLCDNKIQSVPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKIRSISYTPYDLPGNLLRYLGSASNCPNPKCGGVYFDCCVRQIKFVDFCGKYRLPLMHYLCSPECSSPCSSASHSSTSQSESDSEDEASVAAHRMQKVLLG
What are the official names of this protein?
Leucine-rich repeat-containing protein 58.
Protein: PROA_NITWN
Sequence: MKAIGAPADLPVLMGDLAAQAREAARSLGLASTAQKNEALDAMARAIRSNAAAILQANAQDVADARAGGATAAFLDRLTLTQARVEAMADGVKVVREIDDPVGRVTERWQRPNGMTIERVRVPLGVVAVIFESRPNVCADAGVLCLKSGNAVILRGGSESFRSCRAIHACLVEGLREARLPEAAITLVPTRDRAAVGLLLSGMNGGIDVIVPRGGKSLVARVEAEARVPVFAHLEGVNHVYVDGAADLAMAKAVVLNSKMRRPGVCGAAETLLVDRSGVRDILKPLVEALIEAGCEVRGDSDVQGVDPRVRSAADSDWNTEYGDAIISARVVDGCGGAIDHIQRHGSRHTDAIVTEDPETAARFLNEVDSAIVLHNASTQFADGGEFGFGAEIGIATGKFHARGPVGAEQLTSFKYRVHGDGQVRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHA2_STAAB
Sequence: MSLVYLLIAILVIMAMILLMSKRRALAKYAGYIALIAPVISSIYFMIQIPSVAKLQYLSTSIPWIKTLDINLDLRLDGLSLMFSLIISLIGIAVFFYATQYLSSRKDNLPRFYFYLTLFMFSMIGIVLSDNTILMYIFWELTSVSSFLLISYWYNNGDNQFGAIQSFMITVFGGLALLVGFIMLYIMTGTNNITDILGQADHIKNHGLFMPMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLLRFTPLLGLSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMVMVGIGGGYAQHQQDAIASIYTFVLFGALFHLMNHAIFKCALFMGVGILDHEAGSRDIRILSEMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQLSQFSLISMIAIVFVGVIASVFTFTYALYMVKEVFWTKYDSKVFTKKNIHEPWLFSLPSLILMVLVPVIFFVPNIFGKGIIVPALRAVSAGNHQIDQLAPHVSQWHGFNIPLLLTIIIILLGSVLAIKVDWKKVFTGKIRQISVSKSYEMVYRHFEKFATKRFKRVMQDRLNQYIIMTLGIFMVIIGYGYIRIGLPKVHQLHVSEFGPLEVILAIVTVTIGISLIFIRQRLTMVILNGVIGFVVTLLFIAMKAPDLALTQLVVETITTILFIVSFSRLPNVPRSNANKKREIIKISVSLLMALIVVSLIFITQQTDGLSSISDFYLKADKLTGGKNIVNAILGDFRALDTLFEGLVLIITGLGIYTLLNYQDRRGQDERE
What are the official names of this protein?
Putative antiporter subunit mnhA2, Mrp complex subunit A2, Putative NADH-ubiquinone oxidoreductase subunit mnhA2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FER1_PSEPK
Sequence: MTFVVTDNCIKCKYTDCVEVCPVDCFYEGPNFLVIHPDECIDCALCEPECPAQAIFSEDEVPSGMENFIELNAELAEIWPNITERKDALPDAEEWDGKPGKIADLER
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin 1.
Protein: GYRA_STRPN
Sequence: MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVDGHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPARFPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTGALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVRLVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAIQNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIRIIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIADLADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLSNRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRLKGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTSVKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRIATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAKITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQIVTFTTVAVAEKEEVGTENETEGEA
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATD_SALTY
Sequence: MFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQALKLARRYPHCWSTAGVHPHDSSQWSPASEDAIIALANQPEVVAIGECGLDFNRNFSTPQEQERAFQAQLQIAAELQIPIFMHCRDAHERFLVLLDPWLDSLPGAILHCFTGSRQQMQACVDRGLYIGITGWVCDERRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTSRRNEPAYLPHILERIALWRGEDPQWLAAMTDANARTLFEVVF
What is the function of this protein?
3'-5' exonuclease that prefers single-stranded DNA and RNA.  May play a role in the H(2)O(2)-induced DNA damage repair.
What are the official names of this protein?
3'-5' ssDNA/RNA exonuclease TatD, DNase TatD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEH_ALKCK
Sequence: MDTMGRHVISELWGCDTNKLNNMEFIEQVFVNAALRAGAEVREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYASIDVYTCGPVIDPNVAAEFIARELNATTSEVLELPRGMGPVKPEKRLSHSAVK
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: IF1_ACAM1
Sequence: MAKQDAIEMEGTVTESLPNAMFRVDLDNGFNVLAHISGKIRRNYIKILPGDRVKVELTPYDLTKGRITYRLRKK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_PSEA8
Sequence: MTLSRDDAAQVAKVLSEALPYIRRFVGKTLVIKYGGNAMESEELKAGFARDVVLMKAVGINPVVVHGGGPQIGDLLKRLSIESHFIDGMRVTDAATMDVVEMVLGGQVNKDIVNLINRHGGSAIGLTGKDAELIRAKKLTVTRQTPEMTKPEIIDIGHVGEVTGVNVGLLNMLVKGDFIPVIAPIGVGSNGESYNINADLVAGKVAEALKAEKLMLLTNIAGLMDKQGQVLTGLSTEQVNELIADGTIYGGMLPKIRCALEAVQGGVTSAHIIDGRVPNAVLLEIFTDSGVGTLISNRKRH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_SINFN
Sequence: MLDIKWIRENAGVLDNALAKRGAEPLSASLIALDERRRTVLQSLQEMQSRRNAASKEIGAAMAQKNSELAEKLKAEVAELKDALPAAEEESRRMEAELTDILSRIPNVPLEDVPVGPDESGNVVKRLVGSKPTWNHKPLEHFEIGEGLGFMDFEGAARIAGSRFTILKGQLARLERALGQFMLDLHTQEHGYIEVQPPLLVRDDAMYGTGQLPKFAEDLFRTTDGRWLIPTAEVPLTNMVREQILEGEKLPLRFTALTPCFRSEAGSAGRDTRGMLRQHQFNKVELVSLTDAETSVDEHERMTACAEEVLKRLGLHYRVMTLCTGDMGFGARKTYDLEVWLPGQDAYREISSCSVCGDFQARRMNARYRSKEEKGTKFVHTLNGSGVAVGRALIAVIENYLNEDGSVSVPEVLVPYMGGLRRVEKAA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT5F1_CAEEL
Sequence: MSLSRLSSPQTFSRVFIVARGAATGHAVAPSSDNSIGYFEKIAYRFKGIPLPTETEAPKSMFDACNKEWSAPELLPSVPKDFKEHPDRDLTNYPYPSRPMYPPKTRLLMMPDSWFTAFQKVTGTSGPYLFFGGLFAFLVNKELWVFEEQGHMTVGWILFYLLVSRTAGYKIDAGLYKDYQERVGFFKGLIQEDLKEAVDFRKTSAAQTASFAALKEGMPTSLKDSMQLQLEAAYRKNVQTISNEIKRRIEYLKETEETKARFERDQLLKLINDSVEKQVSQKDFQEKFLQNAIQQLKGIAV
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the subunits of the catalytic subcomplexes relative to the rotary elements (Probable).  Plays a role in germline development (PubMed:17223323).
What are the official names of this protein?
ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase peripheral stalk-membrane subunit B1, ATP synthase proton-transporting mitochondrial F(0) complex subunit B1, ATP synthase subunit B1, ATPase subunit B1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase B chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: SYB1_CAEEL
Sequence: MDAQGDAGAQGGSQGGPRPSNKRLQQTQAQVDEVVGIMKVNVEKVLERDQKLSQLDDRADALQEGASQFEKSAATLKRKYWWKNIKMMIIMCAIVVILIIIIVLWAGGK
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane.  Acts in neuronal exocytosis of synaptic transmission.  Likely to have a role in cholinergic transmisson.  Required for viability, coordinated movement and M3 pharynx motor neuron function.
What are the official names of this protein?
Synaptobrevin-1, Synaptobrevin-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell membrane. Synapse, synaptosome. Note=Observed in discrete synaptic vesicle puncta along the ventral cord. Functional unc-104, a kinesin-like protein, is required for localization. The two pools of synaptobrevin are recycled by clatherin- and dynamin- dependent endocytosis. AP180-like adapter protein, unc-11, is thought to act as a molecular chaperone.