PharMolix/UniProtQA huggingface dataset:
Protein: NUDL_ECOHS
Sequence: MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: 3608L_ASFM2
Sequence: MLSLQTLAKKAVAKQSVPEEYHYILKYCGLWWQNKPISLCHYCNYIILNSTLFKRELLHLDVALIMAIKENNYDVIRLFTEWGANIYYGLTCARTEQTQELCRELGAKDGLNNKEIFIGLLRHKTSNNIILCHEIFNNNPILETLNIQDFGEEIHRELKFFIFYILDNVPINVLVKYWYAIAIKYKLKRAISFFYQTYGHLNMWRLMCAIYFNNIFDLHEIYEQKIAHMDIDEMMQLACMRDYNFSTIYYCFVLGGDIDQAINVSQWHHQTNNICFCKDLKDLKQNVLTARPLLLPNITDPKKIYTMLKNYLPTSSNSR
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-8L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: SUOX_ARATH
Sequence: MPGIRGPSEYSQEPPRHPSLKVNAKEPFNAEPPRSALVSSYVTPVDLFYKRNHGPIPIVDHLQSYSVTLTGLIQNPRKLFIKDIRSLPKYNVTATLQCAGNRRTAMSKVRNVRGVGWDVSAIGNAVWGGAKLADVLELVGIPKLTASTNLGARHVEFVSVDRCKEENGGPYKASITLSQATNPEADVLLAYEMNGETLNRDHGFPLRVVVPGVIGARSVKWLDSINVIAEESQGFFMQKDYKMFPPSVNWDNINWSSRRPQMDFPVQSAICSVEDVQMVKPGKVSIKGYAVSGGGRGIERVDISLDGGKNWVEASRTQEPGKQYISEHSSSDKWAWVLFEATIDVSQTTEVIAKAVDSAANVQPENVESVWNLRGVLNTSWHRVLLRLGHSNL
What is the function of this protein?
Probably involved in sulfite oxidative detoxification.
What are the official names of this protein?
Sulfite oxidase, Moco-containing protein AtMCP, At-SO, AtSOX.
Protein: RSMA_SALPA
Sequence: MNNRVHQGHLARKRFGQNFLNDRFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDKLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELSAQLGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPYPVKDIRVLSRITTEAFNQRRKTIRNSLGNLFSVETLTEMGIDPAMRAENISVAQYCQMANYLSENAPLKES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KMCP1_RAT
Sequence: MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFREIRYRGMLHALMRIGREEGLRALYSGIAPAMLRQASYGTIKIGTYQSLKRLAVERPEDETLLINVVCGILSGVISSAIANPTDVLKIRMQAQNSAVQGGMIGNFISIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVSTHFLSSFTCGLVGALASNPVDVVRTRMMNQRDLRDGRCSGYKGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFLTYEQLKKLDL
What is the function of this protein?
Probable transporter.
What are the official names of this protein?
Kidney mitochondrial carrier protein 1, Solute carrier family 25 member 30.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: WSCD_DROPS
Sequence: MALQGWRFFGVSATIIIYIGGVLFLSMNNIPGSHPKRPRIERFAEFPSFHSPRFPMPSRKMTIRWCRDLKYMNRDLPNYTDYRADFYTLPSDVSASLQASPMLTALASFPGSGNTWLRYLLQQATGILTGSIYKDYGLLKTGFPAENVCNSSVLLVKTHEWGGKSWAPFAKAILLVRDPEKAIIAEFNRQSGGHIGFASPDRYKRTKGKYWQQFVSNKLKGWELMNLSWARNFTGSIKVVFYDDLVHHTERELRAILEFLQFPVDETLLRCAILRKEGIFRRKKRLLSFDPYTEAMRAQVQARKRIVYSLLGRKEH
What are the official names of this protein?
WSCD family member GA21586.
What is the protein family that this protein belongs to?
Belongs to the WSCD family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CUSA_ECO57
Sequence: MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQDWFLKYELKTIPDVAEVASVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKIQVGPEMRRGIAELNGEVVGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITNASVEVGPALFISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQINEGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQEQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADIDAMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITLADVADVKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLNNPQTFSEQKLDEALHHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKLMWLHRHRVRK
What is the function of this protein?
Part of a cation efflux system that mediates resistance to copper and silver.
What are the official names of this protein?
Cation efflux system protein CusA.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS8_THEGJ
Sequence: MISELVKSFQPYRVVEGNYRIRLDKNENPYDLPGEVKEEIFEELREVSFNRYPHITSMPAREAIADFYGVSPDNVAVGNGSDELLSYLVRLFEGNHIVITPPTFGMYSFYAKLNGVPVVEVPLREDFTLDGEAVAEKAKNARVVFIASPNNPTGNLQPEEEIIRVLETRRPVVLDEAYAEFVGKSLWRLIEEYPNLVVLRTFSKAFGMAGIRAGYMLAGEEIVDALYRIKSPFSVGIMTMTAIRVALRHADLMEKTVRKIVEERERMRRKLGELAYPSDANFLLVRLNAYEELLKRGIVVRKLSGRLEGHIRVTVGRRWENDAFLEAVEEIAGGESVGGL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RS102_ARATH
Sequence: MIISETNRREISKYLFKEGVLFAKKDFNLPQHPLIESVPNLQVIKLMQSFKSKEYVRETFAWMHYYWFLTNEGIDFLRTYLNLPSEIVPATLKKQQKPLGRPFGGGGDRPRGPPRGDGERRFGDRDGYRGGPKSGGEYGDKAGAPADYQPGFRGGAGGARQGFGRGAGGFGGGAAGSDLP
What are the official names of this protein?
40S ribosomal protein S10-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDD_SALTI
Sequence: MINPNPKRSDEPVFWGLFGAGGMWGAIIAPVIVLLVGIMLPLGLFPGDALSFERVLTFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTAIGVITL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS18_SYNS3
Sequence: MSSSFFKKRLSPIKPGDPIDYKDVDLLKKFITERGKILPRRLTGLTAKQQRDLTNAVKRARIVALLPFVNPEG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CYB_ANOGA
Sequence: MFKPIRKTHPLISIANNALVDLPAPSNISAWWNFGSLLGLCLMLQILTGLFLAMHYAADIETAFNSVNHICRDVNNGWFLRICHANGASFFFACLFIHVGRGVYYESYLYHMTWNTGVIILFLTMATGFLGYVLPWGQMSFWGATVITNLLSAVPYLGMDLVQWIWGGFAVDNATLTRFFTFHFIFPFIILALMMIHLLFLHQTGSNNPLGLNSNVDKIPFHPYFIYKDIFGFIVFLWILVTFIWKFNYLLMDPENFIPANPLVTPVHIQPEWYFLFAYAILRSIPNKLGGVIALVLSIAILLILPFTHSSKFRGLQFYPLNQILFWNMVIVASLLTWIGARPVEDPYILTGQILTVLYFSYFIINPLLAKFWDKLLN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NU2C_TRIEI
Sequence: MIDLSTIAAQLNARTILPEGIVVITLLVVLVGDLILGRSSTKWTPYAAIVGLLGAIVALYTQWDSSNTIGFLGAFNADALSIAFRGIIAISAITTILMSVAYIEQTGTPLGEFICILLTATLGAMFLSGADELVMIFISLETLSISSYLLTGYTKRDPRSNEAALKYLLIGAASSAIFLYGISLLYGLSGGETRLTAIASSMANAGSANISLALVIALVFAIAGISFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPLVSEQWHFVFTALAILSMVLGNVVALAQTSMKRLLAYSSIGQAGFVMIGLLANTEAGYASMIFYLLVYLFMNLGGFTCVILFSLRTGTDQISEYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYWLVLLGLITSVASIYYYIRVVKMMVVKEPQEMSDVIKNYPPISWKLPGMRPLQVGLILSVLATSLAGILSNPLFTLANSSIAKTPMLNSALVKTVEANSVASQLDFSLPSKN
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SVMI_ECHOC
Sequence: MFVSRLAASGLLLLSLLALSLDGKPLPQRQPHHIQPMEQKWLAPDAPPLEQKWLAPDAPPLEQKWLAPAAPPLEQKWLAPDAPPMEQKWLAPDAPPMEQKWLAPDAPPMEQKWLAPDAPPMEQKWLAPDAAPLEQKWLAPDAPPMEQKWLAPDAPPMEQKWQPQIPSLMEQRQLSSGGTTALRQELSPRAEAASGPAVVGGGGGGGGGSKAALALPKPPKAKGAAAATSRLMRDLRPDGKQASQKWGRLVDHDHDHHHHHHPGSSVGGGGGGGGGGARRLKGLAKKGVAKGCFGLKLDRIGSMSGLGC
What is the function of this protein?
Exhibits hypotensive and vasodepressor activity.  Acts by activating natriuretic receptors (NPR1 and/or NPR2 and/or NPR3).
What are the official names of this protein?
Snake venom metalloprotease inhibitor 02D01, 02E11, 10F07, Svmpi-Eoc7.
What is the protein family that this protein belongs to?
In the central section; belongs to the pHpG family.
What are the subcellular locations of this protein?
Secreted.
Protein: NS1_INBSI
Sequence: MAENMTTTQIEVGPGATNATINFEAGILECYERLSWQRALDYPGQDRLNRLKRKLESRIKTHNKSEPESKRMSLEERKAIGVKMMKVLLFMNPSAGIEGFEPYCMKNFSNSNCPNYNWTDYPPTPGKCLDDIEEEPENVDDPTEIVLRDMNNKDARQKIKEEVNTQKEGKFRLTIKRDIRNVLSLRVLVNGKFLKHPNGYKTLSTLHRLNVYDQSGRLVAKLVATDDLTVEDEEDGHRILNSLFERFNEGHSKPIRAAETAVGVLSQFGQEHRLSPEEGDN
What is the function of this protein?
Binds and inhibits the conjugation of the ubiquitin-like G1P2/ISG15 protein to its target proteins.  Since G1P2/ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response.  Prevents EIF2AK2/PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2/PKR.  Also binds poly(A) and U6 snRNA.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza B viruses NS1 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: Y1916_MICAN
Sequence: MYSIDITLKLSPIPISVQRKEEAAADALYQTIINAMRSPNPELLELTCEKQTDKKVAVLSDQISAVIVSQKSGAASTGRAPGFVALATE
What are the official names of this protein?
UPF0367 protein MAE_19160.
What is the protein family that this protein belongs to?
Belongs to the UPF0367 family.
Protein: VPS91_SCHPO
Sequence: MDYPSFHEDPTKDESTVAEQRKGQSNEEKPLIDLNDSLDEQRNAYNEHCKNHDQQPSQQVRNMEDEANQYEQTDSSSDQEVMNEKQSLDKENRNDNIPHENNPGQQEINEPIFDFHMFLEQLRSSSAEPVAKYLKSFLSEFTKRRWTVNYQVKLIRDFLKFINEKIEQYEPWASGSQAEIDNAKEGMEKLVLNRLYTSLFSPEIAKSGIPLSSEHSDDVEEDRVLSEKMELFQWITEENLDIKKQKSSSKFFKLAADELRRINDYHAPRDKIICLLNCCKVIFSYLRNVVKEESADMFVPILIFVVLQARPAHLVSNIQYIQRFRSPEKLTGEVMYYLSTLMGAMSFIETLDCSSLTITEEEFNAQIEKSIKKMEERKLSEKSESKTAVNENATYKDPVLSRGLSSSIDVSTGVALVNLPEELENMKYLQIDTPESKEYPRSTRPRASSHSGSFTTDSGKRSRRNSNKYVGSSDRPPYRVSRAYSSSATHSPIVHEEQPVDDGLQQNDDLREATTASLETAEAERLQAREKAEAITALRAMFPAFDSEVIEVVLNAQQGRLSSSIDSLLEMS
What is the function of this protein?
Required for vacuolar protein sorting; may be required for the consumption of transport vesicles containing vacuolar protein precursors.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 9a, Vacuolar protein-targeting protein 9a.
Protein: DPO3B_SYNE7
Sequence: MKLVCRQNELNTSLSLVSRAVPSRPNHPVLANVLLAADAGTQRLSLTAFDLSLGIQTSFAAQVERSGAITLPAKLLNDIVSRLPNDSDVTLEDNDAAATLSVGSGQYQMRGISADEFPELPLVQSQEALQLSASALIEGLRGTLFATSGDETKQILTGVHLKVQPDGLEFAATDGHRLAVVKTENAAATPATEFAVTVPSRALRDLERMIAIRGSDEAIALYHDQGQTVFQWGDQYLTSRTLDGQYPNYGQLIPREFNRNVAVDRKRLLAALERIAVLADQQNNAIRLSLDPENNRLALAVDAQDVGSGQEAVPAEIIGEPLEIAFNVRYLAEGLKALNTTDIQIQLNSNTSPVVLSPLGPVKITYLVMPIQLRS
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_ECO55
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: NXPH2_BOVIN
Sequence: MRLRPLPLVVVPGLLQLLFCDSEKVVHATEGLDWEDKDATGTLVGNVVHSRIINPLRLFVKQSPVPKPGHLAYADSMENFWDWLANITEVQEPLARTKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGLGNVSVSLVPPSKVVEFEVSPQSTLETKESKSFNCRIEYEKTDRAKKTALCNFDPSKICYQEQTQSHVSWLCSKPFKVICIYIAFYSVDYKLVQKVCPDYNYHSETPYLSSG
What is the function of this protein?
May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.
What are the official names of this protein?
Neurexophilin-2, Neurophilin-2.
What is the protein family that this protein belongs to?
Belongs to the neurexophilin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y448_PSE14
Sequence: MLKKSLAALALGTALLSAGQAMAADYVIDKEGQHAFVDFKISHLGYSFIHGTFKDWDGTFSFDAAKPEASKINVELKTASLFTNHAERDKHISSKDFLDVAKYPEAKFVSTAVKSTGEKTADVTGDLTLHGVTKPIVIKATFNGEGKDPWGGYRAGFNGTSTLNLNDFGIKGPGPTSQTLDLDISFEGVQKK
What are the official names of this protein?
UPF0312 protein PSPPH_0448.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: MSCL_RUEPO
Sequence: MLQEFKTFIAKGNVMDMAVGIIIGAAFTAIVKSLVDDLINPIIGLFTGGVDFTNNFVVLGGDGTAYASLAAAREAGASVFAYGAFFMAVFNFLIIAWVVFMLVKAVNRAKEAAAKEEAAAEPAAPAGPSELDVLLEIRDSLKR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPB6B_ARATH
Sequence: MADDDYNEVDDLGYEDEPAEPEIEEGVEEDADIKENDDVNVDPLETEDKVETEPVQRPRKTSKFMTKYERARILGTRALQISMNAPVMVELEGETDPLEIAMKELRQRKIPFTIRRYLPDMSYEEWGVDELIVEDSWKRQVGGD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  Component of RNA polymerase V which mediates RNA-directed DNA methylation-dependent (RdDM) transcriptional gene silencing (TGS) of endogenous repeated sequences, including transposable elements.
What are the official names of this protein?
DNA-directed RNA polymerases II and V subunit 6B.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL34_MYCGE
Sequence: MKRTYQPSKLKRAKTHGFMARMATAQGRKVLRQRRFKNRAQLTVSSER
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ATPA_CLAMS
Sequence: MAELSISPDEIRDALKDFVQSYEPGKASTTEVGYVLDAGDGIAHVQGLPGVMANELITFADGTLGLAQNLEESEIGVIVLGEFAGIEEGMEVRRTGEVLSVPVGDGYLGRVVDPLGNPIDGQGEIANEGRRALELQAPGVMQRKSVHEPMQTGIKAIDAMIPIGRGQRQLIIGDRQTGKTAIAIDTIINQKANWESGDTNKQVRCIYVAIGQKGSTIASVRGALEEAGAMEYTTIVASPASDPAGFKYLAPYTGSAIGQHWMYGGKHVLIIFDDLSKQAEAYRAVSLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDELGAGSMTGLPIIETKANDVSAYIPTNVISITDGQIFLQSDLFNANQRPAVDVGISVSRVGGDAQVKSIKKVSGTLKLELAQYRSLEAFAIFASDLDAASRRQLARGARLTELLKQPQYSPFPIEEQVVSIWAGTKGKLDEVPVEDILRFERELLDHLHRNTEVLSQLKEKNVLTDDIIDAMDKAVDRFKLEFQTGEGKPLASVGSEKFEPAKAEDVNQEQIVKGKR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CHEB1_CHRVO
Sequence: MSVSVLIVDDSAVVREVLSQMLSSAPDIEVLGAAPDPIFAMTRMKQRWPDVIVLDIEMPRMDGLTFLRKIMDERPTPVIICSSLTEKGARITLDALAAGAVAIITKPALNQRAFLLEAAKELVQEVRDAARAKMGVVKRISQGAAEHAPPAPKLTADVVLEAPSGLEKYRTTEKIIAIGTSTGGTQALEYLLPKLPATCPGVAVVQHMPEKFTASFAERLNRLCRVEVKEAQTGDRLISGVALIAPGGKHLLVKRNGAQYVADVKDGPLVSRHRPSVDVLFRSVAVCAGGNAIGVIMTGMGDDGARGMREMHDAGARTVAQDEESCVVFGMPAEAINHGGVDEVMSLERIAHMLAGIRG
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTSRT_HUMAN
Sequence: MEPPQETNRPFSTLDNRSGQVQVLSATPLLQRNPYSSPDIMHIKGSEASSVPYALNQGTTALPKNKNQEGTGHRLLNMLRKTLKESDSEELEITQETPNLVPFGDVVGCLGIHIKNCRHFMPKISLQHYANLFIRISINKAVKCTKMCSLLSKNDEKNTVIKFDEVKYFSVQVPRRYDDKRNNILLELIQYDNREKRAFLLGSVQIHLYEVIQKGCFIEEVQVLHGNIFVCRLEVEFMFSYGNFGYGFSHQLKPLQKITEPSMFMNLAPPPERTDPVTKVITPQTVEYPAFLSPDLNVTVGTPAVQSSNQPSVVRLEKLQQQPRERLEKMKKEYRNLNTWIDKANYLESILMPKLEHKDSEETNIDEASENTKSNHPEEELENIVGVDIPLVNEEAETTANELLDNDSEKGLTIPTLNQSDQDNSTADASKNDESTPSPTEVHSLCTISNQETIKAGRIPPLGERQSESMPDRKMKNVFFPLEVKLKDNYPSILKADSSLSEVAFSPKEYNSPSFRPEYIEFKPKFQFQKFNKNGFDPFLRNINKMSVRKRKDQDIYKYRNILGAEVIEHEDQDPPYPAQSKTAGPANTTWAHDPNIFTTKMLETENKLAPDPTINTIKGLDTKNSLKENLPNVSLPSIKGESSRAGNVQANTCHLSKSLNFTPHIEYLKQSMILKSILSENLQDLSDKLFSKPEVSMNSEAREKSSSPLLSIHDKSSSSMEDNVLEKKQDLNNWLSEKDILNSKTTLSQIIKNIPADSFSEGSQIIENIPADSLLEGGQVIKNIPEYSLSEGGQIIKNIPADSFLESGPGQSPEVEEHVSKKHFEADERDFPIKKNSSTKKKHLISEVPNSKSGSSGTVHDYIMRQIFTAPIFSELEIEVKEPSETPMNLENQLPTPWKRSLSSHILFHEENADEIELPQPRSATSQIIQAFPIDTLLESGIIKVIELDKEHHKSSLLGTGITSPKGNLKDSQEYYSEIRSETEPLSEQSIPIIPKDTTSVSRAEFIQEDQNMFPQDSSYYSIANKELYLPRNGQRLCKDKNDLSSTLESLTNSLMDKLSESDEIMLKSFLKNIFNVFFKYNHSERRGQPEKELERLIQPSFTSDTEHLEELQEDFDKADKLDRKPILSPKLRVFLEELSESEVKHLKSELSKQIQHYLVERLSESGHITKEDLPKIYQNLYLMNEKAEQKGPNSFQGKYSETVKEIMSFVNNFNHHFIDKHLEIKLRSFLKEILQNYFLKNISESSLFNETASETIYPNISSLRTKSVSISFHELEQDISKGSFGRRFEINMKYPLSKSLQNYLIALSENELLHLKADLSKHLQSLFIEKLSKSGLMTKKQLEGINQHINLLNSSSIPLKYIKTHLPFRDDCHFVEKHSEKQNKYSRIVQQTTLQTVSEDKLREAELIREKEKKYFPLQNLKGNSSLIKEQKSYYTKEEAKTPSLIKVQPSSNENIQASPLSKSSEILTDILLKKLRKEHVFTQLPQAENSVHKTEIQDPYSWGGKSKITQSKAWCEKTLKMKSLDRKEHVNIYKWTVQEKPEAVLTSYPRIPNARMPREDEYLNRITFPSWQSSTLTHFNTETGEKSKLEDQYCQTLKGNNNNNKKHLVTFAQYKKEIQTLYIKPDEICSEKCAKFPEIQSFQYKVVEDEKNLKPHLFPELFKIEDLKPKVRKERDRVAQPKKSFNKIVRILPTTLPTTRIHLKKSVPRTLLHWTARRTIHDCSDKFEDLHDMTSFTHLKKVKSRSRLLGKSSDDIHNHARHSARPYTAPEVNKQRESYSGKFTSRRMVSSGLVHINDKTSDYEMHKMRPKKIKRGY
What is the function of this protein?
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation.  Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.  Required for CatSper complex targeting and trafficking into the quadrilinear nanodomains.  Targets the preassembled CatSper complexes to elongating flagella, where it links the channel-carrying vesicles and motor proteins.
What are the official names of this protein?
Cation channel sperm-associated targeting subunit tau, CatSper-tau, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein, C2 calcium-dependent domain-containing protein 6.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum membrane. Note=Specifically located in the principal piece of sperm tail.