PharMolix/UniProtQA huggingface dataset:
Protein: EFP_ORITB
Sequence: MKILANAIREGNILEYQNNLWIVSKKPDHTKPGKGGAYIQLEMKNLKTGTKIYERFSSSDYLEKATLEQRNYQYLYQENNHLVLMDLESFEQILVQKSIIASNKLPFLLENTVVTVETYKDEPIRLVLPHTVVVEILETSPNIKGATVTASYKPAILSNGAKIMVPPYLSAGEKIVVKLEDISFVERAK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPE24_MYCTU
Sequence: MNFSVLPPEINSALIFAGAGPEPMAAAATAWDGLAMELASAAASFGSVTSGLVGGAWQGASSSAMAAAAAPYAAWLAAAAVQAEQTAAQAAAMIAEFEAVKTAVVQPMLVAANRADLVSLVMSNLFGQNAPAIAAIEATYEQMWAADVSAMSAYHAGASAIASALSPFSKPLQNLAGLPAWLASGAPAAAMTAAAGIPALAGGPTAINLGIANVGGGNVGNANNGLANIGNANLGNYNFGSGNFGNSNIGSASLGNNNIGFGNLGSNNVGVGNLGNLNTGFANTGLGNFGFGNTGNNNIGIGLTGNNQIGIGGLNSGTGNFGLFNSGSGNVGFFNSGNGNFGIGNSGNFNTGGWNSGHGNTGFFNAGSFNTGMLDVGNANTGSLNTGSYNMGDFNPGSSNTGTFNTGNANTGFLNAGNINTGVFNIGHMNNGLFNTGDMNNGVFYRGVGQGSLQFSITTPDLTLPPLQIPGISVPAFSLPAITLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVGAFSLPGLTLPSLNIPAATTPANITVSGFQLPPLSIPSVAIPPVTVPPITVGAFNLPPLQIPEVTIPQLTIPAGITIGGFSLPAIHTQPITVGQIGVGQFGLPSIGWDVFLSTPRITVPAFGIPFTLQFQTNVPALQPPGGGLSTFTNGALIFGEFDLPQLVVHPYTLTGPIVIGSFFLPAFNIPGIDVPAINVDGFTLPQITTPAITTPEFAIPPIGVGGFTLPQITTQEIITPELTINSIGVGGFTLPQITTPPITTPPLTIDPINLTGFTLPQITTPPITTPPLTIDPINLTGFTLPQITTPPITTPPLTIEPIGVGGFTTPPLTVPGIHLPSTTIGAFAIPGGPGYFNSSTAPSSGFFNSGAGGNSGFGNNGSGLSGWFNTNPAGLLGGSGYQNFGGLSSGFSNLGSGVSGFANRGILPFSVASVVSGFANIGTNLAGFFQGTTS
What are the official names of this protein?
Uncharacterized PPE family protein PPE24.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: TGRD1_DICDI
Sequence: MIHKMYFFLILLFSLFIIVYSAPNRVTRNETSIVYTYSLDSDYYTRFVMYLNATTLRTDIAPNYFDCSQIVNSERYCVFHFADSFSRLWGAVYSRVCTRTVSDPTEDCQSTWITDNAFPEPLNVKFSGYPSTSGGDVVFTGLFLRLAGGPNTLANSFTNPSKTFLIKVHGNFSDPNFNCNNFTATFPPSSGYIKVYFDDTGKSSLQLRYASPTVSSFILDESKKLVTINGDNYFTKNSLVQVFFDGIIQNNINITVNHSQIQVNNFIRVDPGPMSVNITINAVSIDNNYTYCFPAVISSISSVSNHLGGVVTIKGSKLSSTSIIPTIKIGDKQCTFIKSTTTELECQLEPNETGGKHLPVDVNFGGCNSTSSGSDAVTFTYSIPTLSSGTLSNGIVTLIGTNLGTINDSFIQLNSNGAIDNVKNDQFNISSDETTATFKLPLLKCKSFYINFTRVDISANNKPSISAPLLIYVINKPTVSNGSINIELYYIDCPISPSSTPSITVGNSSSATQCSIPSLKNLSEYYQTTCSIPYGTGTNKQFKFKYNSEESNSEFSYEPPKVESRSFSKGLFNITINGNNFGNSTSLIKVYFNGSDISSEIQSLNDNQFTFKRLNSYENGPINITVDGNSNMEPSFYLTLPPVIYSIINKENKTIGCGGLITISGKNLLTSDDKFKVRVLANNENTTVIVPDEKTLIVRANNKDSPLFVSTLIGDDLGPNTTLTYFEPRITVIPTVKNKKDGISIRVGGVSLSGIINASLGISSENVSLSCDLQCSLSPNETFYLSNPILSSNEKDITNSTDCLSCHSMNSIVVDETSGVLYLQLGPTSYHYDVKIEEIQSSLNPSSSNGGERKSSKLSGGAIAGITIGCVAGAGALVGSVFYFKLITRVKKAFN
What is the function of this protein?
May be involved in the regulation of aggregation.  Activates tgrC1.
What are the official names of this protein?
Tiger protein D1, Loose aggregate C2 protein, Loose aggregate D1 protein, Transmembrane, IPT, Ig, E-set, Repeat protein D1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein; Extracellular side.
Protein: RL19_SYNAS
Sequence: MNVITMLEREQMRGDIPDFRPGDTVRVHIRIIEGQKQRIQAFEGIVIRKKGGLSQASFTVRKISYGIGVEKTFPIHSPSIDRIDVVTRGRVRRARLYYLRGLQGKKARIKELRKV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: DHAA_MYCSX
Sequence: MSEIGTGFPFDPHYVEVLGERMHYVDVGPRDGTPVLFLHGNPTSSYLWRNIIPHVAPSHRCIAPDLIGMGKSDKPDLDYFFDDHVRYLDAFIEALGLEEVVLVIHDWGSALGFHWAKRNPERVKGIACMEFIRPIPTWDEWPEFARETFQAFRTADVGRELIIDQNAFIEGALPKFVVRPLTEVEMDHYREPFLKPVDREPLWRFPNELPIAGEPANIVALVEAYMNWLHQSPVPKLLFWGTPGVLISPAEAARLAESLPNCKTVDIGPGLHFLQEDNPDLIGSEIARWLPALIVGKSIEFDGGWAT
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.  Has a broad substrate specificity, which includes mono- and di-chlorinated and brominated alkanes.  The highest activity was found with 1,2-dibromoethane, whereas low activity was measured with the analog 1,2-dichloroethane.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
Protein: MAND_MARMS
Sequence: MKIRSAKVIVTCPGRNLVTLKIETDEGVYGIGDATLNGREKSVVSYLEDHVIPTLIGKDPQRVEDIWQYLYRGAYWRRGPVGMTAIAAVDVALWDIKAKLAGMPLYQLLGGKSREKVMVYGHATGLDIESCLEEVRKHVELGYKAVRVQCGIPGIPTTYGVSKEAGKPYEPADSALPAEHVWSTEKYLNNVPELFAAVRKEFGEDLHILHDVHHRLTPIQAARLGKEVEKFHLFWLEDCTAVENQSSYELIRKHTTTPLAIGEVFNSLSDCQELIQNQLIDYIRATITHAGGITNIRRIADFASVFHVKTGFHGATDLSPVCMGAALHFDTWVPNFGIQEHMPHTKETDLVFPHAYEFNDGFFTPGDVPGHGVDIDEEIAAKYPYKPAYLPVNRLEDGTLWNW
What is the function of this protein?
Has low D-mannonate dehydratase activity (in vitro), suggesting that this is not a physiological substrate and that it has no significant role in D-mannonate degradation in vivo.  Has no detectable activity with a panel of 70 other acid sugars (in vitro).
What are the official names of this protein?
D-galactonate dehydratase family member Mmwyl1_0037, D-mannonate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: FRDD_ESCF3
Sequence: MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGVVTI
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BPT_NOVAD
Sequence: MTAPVRFPRFFVTSPAPCPYLPGRSERKVFTELKGANADELNDALGRIGFRRSQTVAYRPSCIDCQACVSVRVVTGEFRPSSTQKRIHKRNRDLEVSICKAWSTPEQFELLQRYLAVRHPGGGMAAMDEMDFADMVEHTPVKSYVIEYREPTVDGSQGRLVGACLTDEQGDGLSMIYSFYDPQHETRSGLGTFIILDHIQRAARAGLPYVYLGYWVEGSERMQYKVRFRPMEKLGRDGWERFEPAEQASAIERAVTARKCEPASLVEGSLKDGVHGAQERYAHI
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG166_VACCC
Sequence: MSRVRISLIYLYTLVVITTTKTIEYTACNDTIIIPCTIDNPTKYIRWKLDNHDILTYNKTSKTTILSKWHTSARLHSLSDSDVSLIIEYKDILPGTYTCEDNTGIKSTVKLVQLHTNWFNDYQTMLMFIFTGITLFLLFLEITYTSISVVFSTNLGILQVFGCVIAMIELCGAFLFYPSMFTLRHIIGLLMMTLPSIFLIITKVFSFWLLCKLSCAVHLIIYYQLAGYILTVLGLGLSLKECVDGTLLLSGLGTIMVSEHFSLLFLVCFPSTQRDYY
What is the function of this protein?
Promotes, when overexpressed, the influx of extracellular Ca(2+), leading to membrane permeability and host cell necrosis.
What are the official names of this protein?
Protein OPG166.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG166 protein family.
Protein: ANMK_BEUC1
Sequence: MRVLGMISGTSHDGIDVAVVRFTLDAGGAQLRGVVEHATTVPYPTALRARVAGALPPAQVGMAEVCALDADLGHAFADAAAEAAAAPDVPEPPDLVCSHGQTMYHWVAEGSALGTLQLGSPAWIAERLGVPVVADVRIRDVTAGGQGAPLVPLLDELLLAGASGRTAVLNLGGIANVTVVGDGADPVAYDVGPANALIDAAVAAAGRGAYDADGALAAAGRVHAPLLDALLTEPYYARRPPKSTGKELFDPGYVDRVRRGAGGAAAADLSLEDLVSTLTELTARVVAQDVRRLDVARLVVSGGGVRNPVLLGALTAAVPGVEVVPSDAFGVSVDHKEAVAFALLGWFTAHGLPASVPSATGASGARVLGSVTPGAGPLRLPTPLSTAPSRLRLTS
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ATPE_PSEAB
Sequence: MAITVHCDIVSAEAEIFSGLVEMVIAHGALGDLGIAPGHAPLITDLKPGPIRLVKQGGEQEVYYISGGFLEVQPNMVKVLADTVVRAGDLDEAAAQEALKAAEKALQGKGAEFDYSAAAARLAEAAAQLRTVQQLRKKFGG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TOLB_NITWN
Sequence: MIERNGLQRMPFRLNRRHMISGMASAAVLLGSRQALGQARVQITEGNVAPLPIAIPNFVGGTPSDNEVGAGVAKVITNNLKRSGLFAPIDQAAYIEKITNIDVPPQFANWKTINAQALVTGRMTRQGDGRLKAEFRLWDVATGQQLAGQQYFTSPEYWRRIAHIISDQIYERLTGEKGYFDSRVVFVDESGSSQRRVKRLALMDQDGANVRYLTRGADLVITPRFSPSTQEVTYMEFGQGDPRVYLFNIETGQREIVGNFPGMSFSPRFAPDGQRIIMSLQQGGNSNLFVMDLRSKSTTRLTDTPAIDTSPSYSPDGARICFESDRGGKPQIYVMGATGGGAQRISFGEGSYSTPVWSPRGDYIAFTKQGGGQFSIGIIKPDGSGERILTSGFHNEGPTFAPNGRVLMFFRDPGGGGGPSLYTIDVSGRNELKVPTPGFASDPAWSPLLS
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ASG1_CANAL
Sequence: MPKREIEDTQSPYSSTGLVSTGESPKTSTSTPTSSTNNRAATTTTNNTSTTSTSLLKSNSNLQPIAMTPSVSSTSLAINKPKSQENKRRRVTRACDTCRQKKVKCDGKQPCIHCTVYSYKCSYDQPNIRNKKNSGIPIPSQPSPAILQVAAQAAVAFGSNNNSSNQQSLQSLQQQQQHVVHQHQHQPLPADEPIPKTNLIIFQQIINALLPKLQLNGFDPNLQFDLNKFQKVVQYVMSKSQTFTLNLNEITELMQDPDSQIPPPPPASSSSSHHRRTLSVGSFDDSSNSAVSSPREVGLHLPSKEVALNLIYTTWNKACVLFRFYHRPSLLEEVDLLYSLDPMNYGDRQQKFLPFLYSILACGSLFSKTPYTMGTPSENEKNLEDDGFKYFLEARKLIDISNVGDINSIQTVVMMIIYLQCSARLSTCYSYIGIALRSALKEGLHRNLTLFQNSKKKLDPIEEDTRKRLFYTIYKMDIYINSLLGLPRSLNEDEFDQLLPVELDDENVTRTEYLFDKQQGRLSSSGCANQHTKLMFILSHIIKKMYPIKVKPEEAENSSNVNYSRDRIHAKVTELEVELKNWLDNLPQELKPIDPSSTTKDVIDEVPEKFRLANYYLHLAFLNCQIILYRPFIHFISDSMDGSSSDPRSLIRGRNCIKVARMVVKLANKMIDHKLLLGTYWFSMYTIFFSIACLIYYFHFANYNNNGQGFNYAGILFDDDLNIDMIKKDIEIGKKVLDNLKNSSNSSLRIYNILNTMFEQLNRRTASRSRQVTATTNSTTTTANTNSNSNSNSQPTTLPANFQNVNVKNTFENFDNMNHFVKKERERERESLSQLFDNTSMAKFESSSEIPKNVANIQRVATPLEENNKEIGEVSGGNLTSNYMPGVFDKLDTQIFGKILPPYMLEKNETMNYNSNNNNSNNVNNNFNNNNNAGEVNNNSNGVAYNNNAANWPLNNAEDGLNLEDLFGTLGNNGNGGTSSSNGLEYLDPF
What is the function of this protein?
Transcription factor necessary to sustain growth on non-fermentative carbon sources such as sodium acetate, acetic acid, or ethanol.  Plays a role in hyphal formation.
What are the official names of this protein?
Activator of stress genes protein 1.
What is the protein family that this protein belongs to?
Belongs to the ASG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YQGF_STAAB
Sequence: MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQLIDKMAAVFILQGYLDSLH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED23_ARATH
Sequence: MDQSQRTVAATPSSSRSYQFHPARAAIIDLFNLYLGRGSRQKPDESLRDPPNKSQKRVHAPNRDLPPRNEQFLLDFELLQSQFNDPEQLRTITESVLISLVVQCSNHAPRAEFLLFALRTLCRISYINWDTFLPSLLSSVSAAEASLSQGVQAAAATAGSSATSSQSVVPVSVNPTSLLPSAHGIGSPSASEVKSVENGQQIARAGQIVRENAMRNSQRIRAAAVNSLRQLSCKIILIGVESSLKPVTHAEIFQYMMNWLVNWDRRDLGTEDSVGKSWRSEKTLAEWLRSCLDVIWLLVEEGESRIPFYELLRSGLQFIENIPDDEALFTLIMEIHRRRDAMAMHMLMLDQHLHCPSFGTHRIVSQITANVPPEAVPHLRHSPITYPSVLGEPLYGEDLAMSIPKGSLDWERAVRCIRHAIRTTPSPDWWKRVLVVAPCYRPSTQAGPIPGAVFTSDMICEAIIDRIVELLKLTNSGNDCFGIDLVSVTFPPLYADANCWQEWLVFSDIFFFLIKSGCTDFVDFIDKLVLRLNGVDNHILRTNHVTWLLAQIIRVELVMTALNSDAKKVETTRKILSFHREDRNSDPNNPQSVLLDFVSSCQNLRIWSLSTTTRAYLNNEQLLKGKQIDEWWRSKGERMMDYMNMDDRSIGMFWVVSYTMAQPACETVINWLSSAGMAELPGLQPNDRVMMTQEVTPLPMSLLSGFSMNLCLKLALQMEEALFVSQVVPSIAMVETYTRLLLISPHSMFRSHFSQLAQRNASLLSKPGVTLLVLEILNYRLLPLYRYQGKSKTLMYDVTKIISALKGKRGDHRIFRLAENLCMNLILSLRDFFSVKREGKGPTEFTETLNRITIMTLAITIKTRGIADPDHMVYLQTMLEQILATSQHTWSEKTMRHFPSLLRETLKGRVDKRGLSIQAWQQAETTVINQCTQLLSPSAEPAYVSTYLSHSFPQHRQYLCAGACLLMQGHAENINSTNLARVLREVSPEEVTANIYTLVDVLLHHVHVDLQQGQSLEAVLDKAGANLAFFFWTHEMLPLDIFLLALIDRDDDPHALIIAMSLLKTPDLLLRIKNYCQNRGSPEHWLVTQVFKRNELQKALGNHLSWKDRYPTFFDDIAARLLPVIPLVLYRLIENNAMEQADNLLLAHSHFLAYHPLRFTFVRDILAYFYGHLPGKLVLRMLKVLDLSKIPFSESFPQYISPTGAPVCPPLDYFASLLLNLVNNVIPPLSSSSNCSSRSGSMADILNSSARPPHGKTPGTSQPGPANASEGQKAFYQIQDPGTYTQLVLETAVIEILSLPVSAAQIVSSLVQIIVNIQSTLIQSGNGFHGAANGVGQGSVLPTSPSGGSTDSMSASRSTCLIPGINTASFVSRSGYTCQQLSCLLIQACGLLLAQLPPDFHVQLYLEAARVTRETWWLKDGKRSQGELDSAVGYALMDPTWAAQDNTSTAIGNIVALLHAFFSNLPQEWLDGTNAIITNLRPVTSVAMLRVVFRIMGPLLPRLASTHTLFNKTLMLLLSALVDVFGKTAQTTAPVEASQIADLIDFLHHIIHYEGQGGAVQTSSKPRPDILALIGRAAETLRPDVQHLLAHLKTNPNSSIYAAAHQQNTAKTNTS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 23.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 23 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSLO_STRP1
Sequence: MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGRTLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATGEVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNVLLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIYGDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQFNESDLEAIISDKA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUCB_BACSU
Sequence: MKKWMAGLFLAAAVLLCLMVPQQIQGASSYDKVLYFPLSRYPETGSHIRDAIAEGHPDICTIDRDGADKRREESLKGIPTKPGYDRDEWPMAVCEEGGAGADVRYVTPSDNRGAGSWVGNQMSSYPDGTRVLFIVQ
What is the function of this protein?
Degrades both double-stranded linear and covalently closed circular DNA.  Likely to play a scavenging role in order to supply nutrients under starvation conditions.
What are the official names of this protein?
Sporulation-specific extracellular nuclease.
What is the protein family that this protein belongs to?
To B.subtilis NucA/ComI.
What are the subcellular locations of this protein?
Secreted.
Protein: RS15_STRPQ
Sequence: MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIKEHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FABZ_PROMA
Sequence: MTNSPSSPVVLTNEEIMGLLPHRYPFALVDRVVEYEPGKSATGIKNVTINEPHFQGHFPGRPLMPGVLIVEAMAQVGGLIVKQIPDLPKGLFVFAGIDSVRFRRPVVPGDQLLINCELISIKRQRFGKVKGEAKVDGNLVCSGELMFSLVD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTND_GLUDA
Sequence: MSHLTVYRDDDPDDIVLRTDDAAVIADALRGIGARFERWDSPVVPPLDATPDAVLNTYRPYLDELMGETGAGSADVVRINAATPNLTALRDKFLSEHTHSEDEVRFFVHGSGNFVLHVDGRVYDVCCTAGDLISVPRGTPHWFDAGLSPDVVALRVFTDTTGWIADYTGDDIARRFPVS
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: EX7L_STRPN
Sequence: MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYFSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDGVGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEKRMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_MARN8
Sequence: MPDPGNRRLLAFDFGTRRIGVASGQEMLGTGQPLAMLPARDGIPDWQQIEALLADWQPDIVLVGLPLNMDDTENEMCARARKFGKRLHGRYHVTVEMVDERLTSYEAKGEVMAGGGSRDFGRHGVDDRAAVLILETWCREQAG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFC2_HUMAN
Sequence: MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.  This subunit binds ATP (By similarity).
What are the official names of this protein?
Replication factor C subunit 2, Activator 1 40 kDa subunit, A1 40 kDa subunit, Activator 1 subunit 2, Replication factor C 40 kDa subunit, RF-C 40 kDa subunit, RFC40.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URM1_DROVI
Sequence: MPDLKIILEFSAGAELLFGNIKRRELALDGDQKWTIANLLKWMHANILTERPELFIQESTVRPGILVLINDTDWELLGELDYELQQNDNVLFISTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as Jafrac1, Ciao1, Eip71CD and GILT1.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_SALG2
Sequence: MAQVFNFSSGPAMLPAEVLKLAQQELRDWHGLGTSVMEISHRGKEFIQVAEEAEQDFRDLLNIPSNYKVLFCHGGGRGQFAGVPLNLLGDKTTADYVDAGYWAASAIKEAKKYCAPQIIDAKITVDGKRAVKPMREWQLSDNAAYLHYCPNETIDGIAIDETPDFGPEVVVTADFSSTILSAPLDVSRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHESCPSILDYTVLNDNDSMFNTPPTFAWYLSGLVFKWLKAQGGVAAMHKINQQKAELLYGVIDNSDFYRNDVAQANRSRMNVPFQLADNALDKVFLEESFAAGLHALKGHRVVGGMRASIYNAMPIEGVKALTDFMIDFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_RHIRD
Sequence: MIQKNWQELIKPNKVEFTSSSRTKATLVAEPLERGFGLTLGNALRRVLLSSLRGAAVTAVQIDGVLHEFSSIPGVREDVTDIVLNIKEIAIKMDGDDSKRMVVRKQGPGSVTAGDIQTVGDIEILNPDHVICTLDEGAEIRMEFTVNNGKGYVPAERNRAEDAPIGLIPVDSLYSPVKKVSYKVENTREGQVLDYDKLIMTIETNGSVSGEDAVAFAARILQDQLGVFVNFDEPQKEAEEESVTELAFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLASMGLHLGMEVPAWPPENIEDLAKRYEDQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.