PharMolix/UniProtQA huggingface dataset:
Protein: NOLJ_RHIFR
Sequence: MDIRLDSRRAIQAGPLVTTGRIAGAALRMARPFLGIARRLQFKAKAFELALRSVALQLMNDAMADADEAMEETEEDADALGGPRQEVRAVSDGTIVTEREMTCPQNRYCHECSWTGAAAGQNVAAKGAGAAVPGPNRRTGSGERRGYG
What is the function of this protein?
Involved in efficiency of soybean nodulation and in nodulation delay.
What are the official names of this protein?
Nodulation protein NolJ, Host-inducible protein B.
Protein: DCUP_ACIC1
Sequence: MADVLPRSDGALLRVCRGEPAPVTPVWFMRQAGRALPEYRAARGETPMLQACLDRDLIVELTLQPVRRYRVDAAILFSDITVPLALSGVSLRIEPGVGPVFDQPVRRAADVARIRPLDRGSMTPIVEAVRLLVGELAGIPLIGFAGAPFTLASYLVEGGPSRDHAVTKALMYSDPATWHALLDRLADISREFLLAQIDAGVSVVQVFDSWAGALHPDDYRRYVAPHSGKLLAGLPVPRIHFGVGTGELLPQFRAVGADVVGVDWRVPLDVAARRIGADAVVQGNLDPAVVFAPWPVLEAAVRDVLIRGRAARGHIFNLGHGVLPSTDPGVLAAIVDFVHAWSADRSARGVPTAVDRFGSEHPAAEAAG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_LEGPH
Sequence: MVMTPREIVQELDKHIIGQDDAKRAVAIALRNRWRRMKIKDPVLRNEIMPKNILMIGPTGVGKTEIARRLANLAKAPFIKVEATKFTEVGYVGRDVDSIIRDLTDMAIKQEREFAMKKVEHLAEDAAEERILDVLLPPARGTLTPGEKNTTARQVFRKQLREGELNDNEIEIEVAATPVGIEIMAPPGMEEMTSQLQSMFQQVGSYRTKTRKMTVAKAMKILREEEAAKLINEEDIKLKAIESVEQNGIVFIDELDKIAKRSDTVSGGDVSREGVQRDLLPLVEGTTVSTKYGMVKSDHILFIASGAFHVAKPSDLIAELQGRLPIRVELSALSVEDFVRILTEPSASLTLQYSALMETEGLTLTFDETGIRRIAEVAWQVNERTENIGARRLYTVMERLLEVVSFEATDKAGETVHVDKAYVDKNLGQLIADEDLARYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_PHYMT
Sequence: MLMPKRTKYRRPHRLSYEGKVKGKNLIVNGNYGLIAQEGNWITNKQIEAARIAMTRHMKRTGKVWINIFPHLSLTRKPLEVRMGSGKGAPEEWVAVVKKGKVLFEVSDLNNSVKAELEALRLASHKLPIKTKIVKKGEQK
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: GRPE_ACIB5
Sequence: MANEQNEQAQDIQNEQVEQSNEQTQAEGVEQANDVTVESLQAQITKLEENLKLEKARTANAVYEAQKSVERIQRESEKHKETVLEKFAKELLDSVDNLERAIQAAGDEETPVLEGVKLTLKSLLTTLEKFGVVEADTQNGFNADLHQAVGIDPNAKANEIGTVLQKGYTLNGRLLRPAMVMVGQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHAE_ALLVD
Sequence: MSNTNFFNDDWLELQRKYWDNWTDMSRKAMGLDSASSSATTPWEAAIDQWWKAMAPAAPDLSRSFMEKMMEQGKNFFRLADTFAKRADEGNAGNGLELWTKTLEDMQKRFSGSLDDGGNTMQRLMSFWELPLDNWQRMMSSMSPMPGDMLRNMPHEQFKDSLDRALSAPGLGYTREEQSQYQELMRSAMEYQAALQEYTNVYTKLGMKSVEHMGSYIQGVIDSGKTIDSARALYDNWVACCEGAYADEVATPEYARIHGRLVNAQMALKKRMSILVDENLGALNMPTRSELRTLQDRLQETRRENKALRHSLHSLERRVAALAGEEPATKPATALRSPAPAAKAPARRRTTKTNPAD
What is the function of this protein?
Polymerizes D(-)-3-hydroxybutyryl-CoA to create polyhydroxybutyrate (PHB) which consists of thousands of hydroxybutyrate molecules linked end to end (PubMed:7957260).  This subunit has no catalytic activity but enhances the activity of PhaC, the catalytic subunit, 100-fold (PubMed:9888824).
What are the official names of this protein?
Poly(3-hydroxyalkanoate) polymerase subunit PhaE, PHA polymerase, ORF2, PHB synthase subunit PhaE, Poly(hydroxyalkanoic acid) synthase subunit PhaE, PHA synthase, Polyhydroxyalkanoic acid synthase, Poly-beta-hydroxybutyrate polymerase subunit PhaE, PHB polymerase, Poly(3-hydroxybutyrate) polymerase.
What is the protein family that this protein belongs to?
Belongs to the PHA/PHB synthase family. Type III PhaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with poly(3-hydroxybutyric acid) granules (PHB) when grown under 'storage' conditions.
Protein: AAEX_PECCP
Sequence: MSSLPVMVLFGLSFPPVFFVLLVSLTLFFVVNCLLQPTGIYDFVWHPALFNSALFCCLFYLLFRYGL
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTF_GROPO
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic hormone, HTH, Adipokinetic hormone 1, GroPo-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: PHNC_BORPA
Sequence: MATSLRITGLVKEYRAGKPVLNGIDLDIAGQGLTAIIGPSGTGKSTLLRCINRLIEPTSGEIVLKDAEGTVDLARVRGQSLRRARRRIGMVFQEYNLVERLTVMENLLTGRLGYTSALNAWMRRFDPADIERAFQLLDTVGLAGFADQRADALSGGQRQRVGIARALMQRPQLLLADEPTSSLDPKTSVEIMKLLTEQGSVNGIPVLVNIHDVELARRYANRIVGMSGGHVVYDGDGKGLDATMLKTIYGGESWLE
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RPOZ_STRM5
Sequence: MARITVEDCLEVVNNRFELVMMASKRARQLANGVQATLDNSETEDKPTVLALREIAARKIDNALIDEVEKAERERAEREALEWAAAEVVADEDMSKNDD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SYW_BORPA
Sequence: MNTRVLTGITTTGTPHLGNYAGAIRPAIQASTQPGVDAFFFLADYHALIKCDDPARVARSRLELAATWLAAGLDPERVTFYRQSDIPEITELCWLLTCVTPKGLMNRAHAYKASVDQNAAKGVEPDDGVTMGLFSYPVLMAADILLFNANQVPVGRDQVQHLEMARDIAQRFNHLYGREFFVLPEVVIAEEVATLPGLDGRKMSKSYNNTIPLFEGGAAGLRNATQRIVTDSRLPGEPKDAEASHLYMLYRAFSTQQESMAFRRQLEEGMGWGDAKQALYERLERDLAPMRERYVELISNPGLIEDILQAGAAKARKLAQPLVRTLRDAVGLGALQPAAAKAAQPARKAAKDARFVSFRDEDGSFRFRLLAADGEELLCSVPFANPKEAGALMRRLQDEAPEQALRGHDDVSYAAWLDGKEVAYGPQAADAGARDALLAKAREALAQLAAA
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP13A_YEAST
Sequence: MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRPITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty1-PR2 Gag polyprotein, Gag-p49, Transposon Ty1 protein A, TY1A, TYA, p58.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGT_MANIN
Sequence: MSASDALNSCPHVALLLSSGMGHLTPCLRFAATLVQHHCRVTIITNYPTVSVAESRAISLLLSDFPQITEKQFHLLPFDPSTANTTDPFFLRWEAIRRSAHLLNPLLSSISPPLSALVIDSSLVSSFVPVAANLDLPSYVLFTSSTRMCSLEETFPAFVASKTNFDSIQLDDVIEIPGFSPVPVSSVPPVFLNLNHLFTTMLIQNGQSFRKANGILINTFEALEGGILPGINDKRAADGLPPYCSVGPLLPCKFEKTECSAPVKWLDDQPEGSVVYVSFGSRFALSSEQIKELGDGLIRSGCRFLWVVKCKKVDQEDEESLDELLGRDVLEKIKKYGFVIKNWVNQQEILDHRAVGGFVTHGGWNSSMEAVWHGVPMLVWPQFGDQKINAEVIERSGLGMWVKRWGWGTQQLVKGEEIGERIKDLMGNNPLRVRAKTLREEARKAIEVGGSSEKTLKELIENWKKTSRKT
What is the function of this protein?
Benzophenone C-glycosyltransferase involved in the biosynthesis of mangiferin.  Exhibits a robust regio- and stereospecific C-glycosylation activity toward over 35 substrates from 18 structurally different types with UDP-glucose.  Also able to produce O- and N-glycosides and to use UDP-xylose as sugar donor.  Generates only C-glycosides with 2,4,6-tri-hydroxy acceptors at the A ring, both C- and O- glycosides with 2,4-di-hydroxyl acceptors at the A ring, and only O-glycosides with 2- or 4-mono-hydroxy acceptors at the A ring.
What are the official names of this protein?
UDP-glycosyltransferase 13, MiUGT13, C-glycosyltransferase, MiCGT.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: HTPX1_METAC
Sequence: MKNMLRTTVLLASLTGLLVLIGDYFGGTGGMIIAFLFAVIMNFGSYWYSDKIVLKMYRAREVTPAESPNLHRIVDGLALKANIPKPKVYVVDSGMPNAFATGRNPQHAAVAVTTGILNLLSYEEIEGVLAHELAHVKNRDTLISAVAATFAGVITMLATWARWAAIFGGFGGRDDDNGGIIGFIVMAVLAPLAATLIQLAISRSREFAADEEGARISKKPWALADALEKLEYGNSHFQPSIRDVQAKETSAHMFIVNPLKGGTLQSLFRTHPVTDERVKRLRAMRF
What are the official names of this protein?
Protease HtpX homolog 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIDD_BORAP
Sequence: MNIFKIFFILNYTIIFLIKIYQNTFSKLFGQQCIYKPTCSKYSIECLKKYNFLTALVLMTLRTIRCNALFKGGNDFIPKYNPISTSLKEFQKRLIK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SPEE_LEPBP
Sequence: MEIWYTEKLELEKGRAVSYRVTKTIESLQSPFQKIDIFETQSFGRMFTLDGVTMVTNKDEHSYHEMIAHIPMMSHPNPESVLVIGGGDGGTVREVLKHPSVKEVVLCEIDKAVVDISYKYFPECADAMKDPKVIHHYDDGAKFARDNKGRFDVILVDSSDPVGPAEVLFKEPFFRDMASALKPTGIIATQAESFWYHGDVITSLFEFIPKIFPEYGYYYTTIPTYPSGIIGFTFLSNAIDPYAVTPDPKRVPKGLKYYSPEIHKAAFVLPEFAKAYIKRKG
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_VIBPA
Sequence: MKKAVVVFSGGQDSTTCLVQALKEFDEVHAITFDYGQRHKLEIEVAQKIAKDLGVKAHKVMDVGLLNELAISSLTRDDIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGADTVITGVCETDFSGYPDCRDDFVKSMNTALVKGMDRALTIKTPLMWLNKAETWALADQYNALQLVRENTLTCYNGIIGDGCGDCPSCDLRKAGLDEYLNNKDAVMKSLVQKQESEGL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: G3P_PARBA
Sequence: MVVKVGINGFGRIGRIVFRNAVEHDDVEIVAVNDPFIETKYAAYMLKYDSTHGQFKGDIQHSSSNNLTVNNKTIHFYQERDPANIPWGKHGVDYVVESTGVFTTTEKAKAHLSGGAKKVIISAPSADAPMFVMGVNEKSYRPDISVLSNASCTTNCLAPLAKVIHDNFGIAEGLMTTIHSYTATQKTVDGPSHKDWRGGRTAAQNIIPSSTGAAKAVGKVIPALNGKLTGMAMRVPTANVSVVDLTCRTEKPVTYDQIKAAVKAASEGELKGILGYSEDALVSTDLNGDPRSSIFDASAGIALNDRFVKLISWYDNEWGYSRRVLDLIAYIAKVDAGK
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_METTP
Sequence: MRRIGVIALQGDVSEHISAIEAAGGQAVPVRRAGIIPTCSGIVIPGGESTTISRQLERTGIAAEIKQAAANGTPVLATCAGLVLAAKEIDAGDVKPLGLIDISVGRNAFGPQRESFEAEINVEGFDRPYRAVFIRAPVVLRCGEGVEKLARFGGRTVAVRQGNVIGLAFHPELTGDLRFHKMLLEA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: TRUB_LEVBA
Sequence: MNGIIPLYKERGLTSFDCVAKLRHILQTKKVGHSGTLDPSVDGVLPICIGSATKVVPYLMASGKVYRGSVTLGLATTTEDLDGDVVERQPLERPFTADQVAAAAQALTGTIQQTPPMYSAVKVNGRKLYEYARAGETVERPTRTITVDRFDLQGAGTFDATAGTQTIDFEIACSKGTYVRTLAVDLGQQLGVPAVMATLTRLKSGGFTLSQTVTLADVEAAMADDQIERTLRPIDYALQDYPHVALDEHLWALVKNGVFLSAAELNQATEPELALTYQGETKCLYRWSDEKKQYRPLKMFAVN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: NUOM_ECOLI
Sequence: MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMGLTLALSLQLWLQGGYSLTQSAGIPQWQSEFDMPWIPRFGISIHLAIDGLSLLMVVLTGLLGVLAVLCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHKASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYNATGVWTFNYEELLNTPMSSGVEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSLPLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSVSHMGFVLIAIYTGSQLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFAVATLGMPGTGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKSQIASQELPGMSLRELFMILLLVVLLVLLGFYPQPILDTSHSAIGNIQQWFVNSVTTTRP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit M, NADH dehydrogenase I subunit M, NDH-1 subunit M, NUO13.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL36_PSEPK
Sequence: MKVRASVKKLCRNCKIIRREGVVRVICSAEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: T106B_BOVIN
Sequence: MGKSFSHLPLHSNKEDGYDGMTSTENIRNGLVNGEVHNEDGRSGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITSIGPLDMKQIDYTVPTVIAEEMSYMFDFCTLLTIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTTYHLGQSEYLNVLQPQQ
What is the function of this protein?
In neurons, involved in the transport of late endosomes/lysosomes (By similarity).  May be involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking (By similarity).  May act as a molecular brake for retrograde transport of late endosomes/lysosomes, possibly via its interaction with MAP6 (By similarity).  In motoneurons, may mediate the axonal transport of lysosomes and axonal sorting at the initial segment (By similarity).  It remains unclear whether TMEM106B affects the transport of moving lysosomes in the anterograde or retrograde direction in neurites and whether it is particularly important in the sorting of lysosomes in axons or in dendrites (By similarity).  In neurons, may also play a role in the regulation of lysosomal size and responsiveness to stress (By similarity).  Required for proper lysosomal acidification (By similarity).
What are the official names of this protein?
Transmembrane protein 106B.
What is the protein family that this protein belongs to?
Belongs to the TMEM106 family.
What are the subcellular locations of this protein?
Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. Membrane; Lipid-anchor.
Protein: MDM2_XENLA
Sequence: MNLTSTTNCLENNHISTSDQEKLVQPTPLLLSLLKSAGAQKETFTMKEVIYHLGQYIMAKQLYDEKQQHIVHCSNDPLGELFGVQEFSVKEPRRLYAMISRNLVSANVKESSEDIFGNVCCFPDKQSSQKEKLQELPDKLIAPASDSKPCNLSQRKSSNETEEISSVDHPAEQQRKRHKSDSFSLTFDESLSWWVISGLRCDRNSSESTDSSSNSDPERHSTNDNSEHDSDQFSVEFEVESVCSDDYSPSGDEHGVSEEEEINDEVYQVTIYETEESETDSFDVDTEISEADYWKCPECGEVNPPLPSYCPRCWTVRKDWLPEQRRKEPPPSKRKLLEIEEDEGFDVPDCKKSKLTSSQDTNVDKKEAENIQNSESQETEDCSQPSTSGSIASCSQEVTKEDSSKESMESSLPLTSIDPCVICQTRPKNGCIVHGRTGHLMACYTCAKKLKKRNKPCPVCREPIQMIVLTYFS
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.
What are the official names of this protein?
E3 ubiquitin-protein ligase Mdm2, Double minute 2 protein, Xdm2, RING-type E3 ubiquitin transferase Mdm2, p53-binding protein Mdm2.
What is the protein family that this protein belongs to?
Belongs to the MDM2/MDM4 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Nucleus, nucleolus. Nucleus.
Protein: HEMH_SALPC
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSYGSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIRDYADDGAYIDALAKSARESFARHGEPDVLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLEAGGKKYAYIPALNATPEHIDMMLKLTAPYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SR34A_ARATH
Sequence: MSGRFSRSIYVGNLPGDIREHEIEDIFYKYGRIVDIELKVPPRPPCYCFVEFEHSRDAEDAIKGRDGYNLDGCRLRVELAHGGRGQSSSDRRGGYGGGGSGYGGGGGGGGSARFGVSRHSEFRVIVRGLPSSASWQDLKDHMRKAGDVCFAEVTRDSDGTYGVVDYTNYDDMKYAIRKLDDTEFRNPWARGFIRVKKYESSRSRSRSPSRSRSRSRSRSRSRGRGRSHSRSRSLSRSKSPRKDLSKSPRRSLSRSISKSRSPSPDKKKSPPRAMSRSKSRSRSRSRSPSKSPPKVREGSV
What is the function of this protein?
Probably involved in intron recognition and spliceosome assembly.
What are the official names of this protein?
Serine/arginine-rich splicing factor SR34A, At-SR34A, At-SRp34A, AtSR34A, SER/ARG-rich protein 34A.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family. SR subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm.
Protein: Y2650_BACO1
Sequence: MKSIYKYLDTRLFLIGLLVLPFLAVVSCQNDDDDAIPVIHYIRVTDPAKADSTFTDVNPGTMIVVVGEHLGGTQKVYINDQEVSFNRNYVTSTSIILTVPNELELTGQNPELKGEIRIETEHGVAAYNMHVLSPAPYITRISATYPIKPGDQMTVIGGNFYEVQAVYLSTEQPAKDGTRPVDVQEITNYEVNNKYSQITLTAPANLLEEGYLVVECYTSSAVTEFKKNGPKPVVTAVSSTMPVVGSTVTITGQNFIEVSRVNINGEFDIPVGDITTSNTFDEISFVLPQAPTQSGHISVTAIGGTVESAEIFYPLENVILNYDGIGSHVWGDCSFVVADGSSAPYVSNGTCLGITGTVSASNYWWKQSYSNAQWVNTSIIPGNIPIDDLKLQFECFVKEVFTGPVFQIAMCENFDAALNGYVPVSSFTGKTETGKWMQCSVSLSSVVADATYQDFLNRNSTHIGVYATNPGSSQATIEVYFDNFRIVRK
What is the function of this protein?
Polysaccharide-binding protein present at the surface of the cell.  Probably mediates xyloglucan-binding before xyloglucan transport in the periplasm for degradation.
What are the official names of this protein?
IPT/TIG domain-containing protein BACOVA_02650.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Note=Cell outer membrane localization is predicted by analogy with the archetypal sus locus.
Protein: IF5A_MAIZE
Sequence: MSDSEEHHFESKADAGASKTYPQQAGTVRKNGFIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDIPHVNRTEYQLIDISEDGFVSLLTSDGNTKDDLRLPTDETLVAQIKEGFESGKDLVVTVQSAMGEEQICALKDVGPK
What is the function of this protein?
The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Eukaryotic translation initiation factor 5A, eIF-5A, eIF-4D.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
Protein: PRPS2_HUMAN
Sequence: MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL
What is the function of this protein?
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 2, PPRibP, Phosphoribosyl pyrophosphate synthase II, PRS-II.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.