PharMolix/UniProtQA huggingface dataset:
Protein: FABZ_RICRS
Sequence: MIIDITEIMDWIPHRYPFLLVDRVLKIDPNKSITGIKNVTVNEPQFTGHFPARPVMPGVLMVEAMAQLAAILVAKSLGSTKNKEVFLMTIENAKFRRIVQPGDTMHIHAVIDQQRANVWKFSSTVTVEGEIAAESKFTAMIKDKT
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_RHIWR
Sequence: MPGRFITLEGGEGVGKSTQAKALAAALRARGLDVVETREPGGSDGAEAIRRLLLEGAADRWNARAEALLFAAARADHVARTIRPAIEAGRWVVCDRFLDSSIAYQGGADGLGDEAIRTLHAIGSAGYLPDRTLLLDMPVFDAAFRQAEAGIANSDRFEKRDEAFHDRVADSFRRIAAQEPARIRTINAQGSPQEVTARLIEALADLLP
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RUTB_ECO1A
Sequence: MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: IGG2B_RAT
Sequence: AQTTAPSVYPLAPGCGDTTSSTVTLGCLVKGYFPEPVTVTWNSGALSSDVHTFPAVLQSGLYTLTSSVTSSTWPSQTVTCNVAHPASSTKVDKKVERRNGGIGHKCPTCPTCHKCPVPELLGGPSVFIFPPKPKDILLISQNAKVTCVVVDVSEEEPDVQFSWFVNNVEVHTAQTQPREEQYNSTFRVVSALPIQHQDWMSGKEFKCKVNNKALPSPIEKTISKPKGLVRKPQVYVMGPPTEQLTEQTVSLTCLTSGFLPNDIGVEWTSNGHIEKNYKNTEPVMDSDGSFFMYSKLNVERSRWDSRAPFVCSVVHEGLHNHHVEKSISRPPGK
What are the official names of this protein?
Ig gamma-2B chain C region, Immunoglobulin heavy chain 1a.
Protein: MSHR_TRACR
Sequence: MPVQGSQRRLLGSLNSTPTATPRLGLAANQTGARCLEVSIPDGLFLSLGLVSLVENVLVVVAIARNRNLHSPMYCFICCLALSDLLVSGSNMLETAVILLLEAGALAARAAVVQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLRRARRVVAAIWVASVLFSTLFIAYCDHAAVLLSLVVFFLAMLVLMAVLYVHMLARACQHAQGIAQLHKRQRPAHQGVGLKGAATLTILLGIFFLCWGPFFLHLTLIVLCPQHPTCSCIFKNFNLFLTLIICNAIIDPLIYAFRSQELRRTLKKVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACPS_CHLL3
Sequence: MDIVDLVRIEKAYDRYGRKFLERIMTGEEIELCLKKPSPLASIAGRFAAKEAVVKALGTGITAAVHWKSFEVLNDPAGKPFVRSSQPGLLPEGCSIKISIAHDRHSAVATALLCRGPES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF1_BRADU
Sequence: MFFDPETWVAIAFVILMVVFGYLGVFKSAMTALDHRAARIKAELDDATRLKQEAAKVLADYKARSATAEREAADIIANAKVEAERIATEAKAKMEDFVARRTKTAESKIALAEAQAVADVRAAAAEAAVQAASTILSQSVKGQVADDLLAKSISEVRQKLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: METAA_BACMK
Sequence: MPIIIDKDLPARKVLQKENIFVMTKERAVTQDIRALKIAILNLMPTKQETEAQLLRLIGNTPLQLDVHLLHMESHLSRNVAQDHLTSFYKTFRDIEDEKFDGLIITGAPVETLSFEEVDYWEELGRIMEYSKTNVTSTLHICWGAQAGLYYHYGVPKYPLAEKMFGVFEHEVREQHVKLLQGFDEVFFAPHSRHTEVRESDIEKVKELTLLANSEEAGVHLAIGQEGRQVFALGHSEYSCDTLKQEYERDCQRGLNIDVPKNYFKHNNPNEKPIVRWRSHGNLLFSNWLNYYVYQETPYIL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HV226_HUMAN
Sequence: MDTLCYTLLLLTTPSWVLSQVTLKESGPVLVKPTETLTLTCTVSGFSLSNARMGVSWIRQPPGKALEWLAHIFSNDEKSYSTSLKSRLTISKDTSKSQVVLTMTNMDPVDTATYYCARI
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 2-26.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: PTXD_STUST
Sequence: MLPKLVITHRVHDEILQLLAPHCELMTNQTDSTLTREEILRRCRDAQAMMAFMPDRVDADFLQACPELRVVGCALKGFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAADAFVRSGEFQGWQPQFYGTGLDNATVGILGMGAIGLAMADRLQGWGATLQYHEAKALDTQTEQRLGLRQVACSELFASSDFILLALPLNADTQHLVNAELLALVRPGALLVNPCRGSVVDEAAVLAALERGQLGGYAADVFEMEDWARADRPRLIDPALLAHPNTLFTPHIGSAVRAVRLEIERCAAQNIIQVLAGARPINAANRLPKAEPAAC
What is the function of this protein?
Catalyzes phosphite (phosphonate) oxidation.
What are the official names of this protein?
Phosphonate dehydrogenase, NAD-dependent phosphite dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: MRAZ_CLOBA
Sequence: MFIGEYQHSLDSKNRMIVPVKLREDLGEKFVITKGLDGCIYAYTINEWGILENKLKTLPLTNRDARAFVRFFFSGACIVELDKQGRGLIPQNLKEYAGIEKDIVSIGVLSRVEIWSREKWSNYNESDIDYDLIAEKMNDLGI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TSPC_DICDI
Sequence: MVNTRDFLPKTTHYLKVPIIGLNAILWLLGLVLIVVGSVCISFFSNFKEFTKESGYKNALSNLTTSAPTGVLVIGIFFILLTLVGCFVAYKEKLVGLVLYTMLMLILLVVLIGIGGKALTLDKEDAVSIIGTSWVQISNSLKNSTITKLEDFLECCCWSESYSNQTYKDLCPKDDDGNIKYEDTYCEGIFTKQVSSKLVLVGIAGVVIGCIEFVAMALSLFLIIRICRSPRSRAYDQY
What are the official names of this protein?
Probable tetraspanin tspC.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DIF1_YEAS2
Sequence: MDAQLEWASSLVPKRQLQQQQQQEQQQQQQQDFHKDQLMTVGMRIRQRVDQGYASRTPSTSDASLQPGVIRDYSSVIVPQFTRSPLPTANSLPPMLINQRTMSTEASSLEKWDVAEPAAEHEAMVNGSKRRL
What is the function of this protein?
Mediates the nuclear localization of RNR2 and RNR4, 2 subunits of the ribonucleotide reductase.
What are the official names of this protein?
Damage-regulated import facilitator 1.
What is the protein family that this protein belongs to?
Belongs to the DIF1/spd1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: H3_GIBZE
Sequence: MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKSDLRFQSSAIGALQESVESYLVSLFEDTNLCAIHAKRVTIQSKDIQLARRLRGERN
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: UREG_SINFN
Sequence: MPSKNGPLRVGIGGPVGSGKTALTDKLCKAMREKYSVAVVTNDIYTKEDAEALVRMQALPSERIVGVETGGCPHTAIREDASINLQAIADLNRRIPDLDVVFIESGGDNLAATFSPDLADLTIYVISVCQGEEIPRKGGPGITKSDLLVINKKDLAPYVGADLEVMEHDATRMRAEKPFVFSDMKRGEGIERIVEFLTVQGGL
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX819_LYCSI
Sequence: MKLIIFTGLILFAIVSLIEAQANNEKACLPQYQVCTDAPGNCCSNLVCDCYGRYKSGARIGRNCFCLLKGVIYKREN
What are the official names of this protein?
U8-lycotoxin-Ls1j, Toxin-like structure LSTX-H19.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 08 (U8-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PMIP_USTMA
Sequence: MASTSKNAQRAAASVAHSYHVCLARRMSRLPTLLSNISAPAASKALDRYESKRIHSRSFSSSLAAQRVQRPTSAGPILTNPISDHEKDNDELRSLFDAPPTSSSANHLRSSGPSTGLFEIPSLTSPQNFLVLAQQTLARAQLLVDRIDRAGSADASTAQGIKELKEVVRNLDRLSDLLCGVIDMAELVRNAHPDPEWAEAANAAYEYLCGYMNVLNTHTGLYSVLKNILSIKEVAETLSKEATAVAQVFLRDFEKSGIHLPPAERERFVQLSDEILVLGRGFLQDIAGNDASDDFARIASAQADADKSDMVGLPTHWLEDVNPTILKAVRASAITDTDGLLTFSAADQPWVFQTLLKYAPDERARKVAFRAANYGSQAQVQRLERLLKARAELATLTGASSYAEMALGDKMAKEPQNVEEFLRALTKHHRPRASHDLDKLRRLKHNATVSEPAQNTRQSTFNTNSTLPEFAPWDRDMYTEQHFRSASLSNVQPLSPYLSVGSVFAGLSRLFSALYGIRFRASMVAPGEVWSEGAGDVMKVEVLDESEGARGTSGSAEGLIGTIYADLWSREGKPGGAAHYTVRCSRRVDKDDEAGDFTYGRAEDGRVVRPQDLGGEGCGNPLQAPTFEQRERPGRYQLPVVVLMCDFARPGNANQGPCLLGWHEVETLFHEMGHAIHSMIGRTSYHNVSGTRCATDFVELPSILMEHFVSSPQVVHLLARHHSTGASLPFEHLSSHLAASKSLEGLDTYHQILLARLDQLYHSQLAASPSFSSTTTYSDLDRQMHLPGAPNLSYTEGAHPQVRFGHLFGYGSTYYSYLLDRVIASKVWNHLFANNPLDRYAGQVFKNQCLKYGGGKDPWHILADVLNEDSVRQGDSRAMQQVGKWGIEC
What is the function of this protein?
Cleaves proteins, imported into the mitochondrion, to their mature size.  While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial intermediate peptidase, MIP, Octapeptidyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: INLJ_LISMF
Sequence: MKTSKIIIASLVSLTLVSNPILTFAATNDVIDSTTEITTDKEISSTQPTIKTTLKAGQTQSFNDWFPDDNFASEVAAAFEMQATDTISEEQLATLTSLDCHNSSIADMTGIEKLTGLTKLICTYNNITTLDLSQNTNLTYLACDSNKLTNLDVTPLTKLTYLNCDTNKLTKIDVSQNPLLTYLNCARNTLTEIDVSHNTQLTELDCHLNKKITKLDVTPQTQLTTLDCSFNKITALDVSQNKLLNRLNCDTNNITKLDLNQNIQLTFLNCSSNKLTEIDVTPLTQLTYFDCSVNPLTELDVSTLSKLTTLHCIQTDLLEIDLTHNTQLIYFQAEGCRKIKELDVTHNTQLYLLDCQAAGITELDLSQNPKLVYLYLNNTELTKLDVSHNTKLKSLSCVNAHIQDFSSVGKIPVLNNNLDAEGQTITMPKETLTNNSLTIAVSPDLLDQFGNPMNIEPGDGGVYDQATNTITWENLSTDNPAVTYTFTSENGAIVGTVTTPFEAPQPIKGEDVTVHYLDDKGEKLAADEVLSGNLDDPYTSSAKDIPDYTLTTTPDNATGTFTTTSQSVTYVYTKNIVAAEPVTVNYVDDTGKTLAPSETLNGNVGDTYNATAKQIDGYTLSTTPNNATGTFNTSSQTVTYVYTKNIVAAEPVTVNYVDDTGKTLAPSETLNGNVGDTYNATAKQIDGYTLSAEPTNATGQFTSSAQTVNYIYTKNPAPEKGVVEIHYVDENNKQLSSATKISGTVGDNYTTEPKNIDGYTLTTTPDNATGTFNTSSQTVTYVYTKNIVAAEPVTVNYVDANGKTLAPSETLNGTIGDTYNATAKQIDGYTLSAEPTNATGQFTNSAQTVNYIYTKNTNIDQPLPDKKTTKPSNLKTTEVKKASDTLPKTGDSTPWKSALLGVFLSSTALVIWKKKK
What is the function of this protein?
Involved in several steps of L. monocytogenes infection, probably improves adhesin to host cells.
What are the official names of this protein?
Internalin J.
What is the protein family that this protein belongs to?
Belongs to the internalin family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: NHR89_CAEEL
Sequence: MKIPEGPCRVCHSVKGTRRHFGITACMSCSSFFRRSLNCKFYCPANNSCTILDDQKQFCRSCRYNKCVQSGMRRDCVRKQSYRRQAGRKEAKSPAVSCSNKLSESYEELLNFYVKEANESIARKRQSPLKNAHQVKTSKELLEISKSEDKTSLDAVLHCYGTYILDDEDITTLIRYFKFMNTWIDSAFVYSKSTSNEELLDGNDICKFAYQIDTSIGLSLKNLNLNIFEYAALRAICIWNLKFYETSPKMKSLALEHYKGITGALRQYYENYMSDMDIAVRIGEITMQITTISDLFHDLITLHQKYQIPF
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-89.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DBP9_YEAS7
Sequence: MSYEKKSVEGAYIDDSTTFEAFHLDSRLLQAIKNIGFQYPTLIQSHAIPLALQQKRDIIAKAATGSGKTLAYLIPVIETILEYKKTIDNGEENGTLGIILVPTRELAQQVYNVLEKLVLYCSKDIRTLNISSDMSDSVLSTLLMDQPEIIVGTPGKLLDLLQTKINSISLNELKFLVVDEVDLVLTFGYQDDLNKIGEYLPLKKNLQTFLMSATLNDDIQALKQKFCRSPAILKFNDEEINKNQNKLLQYYVKVSEFDKFLLCYVIFKLNLIKGKTLIFVNNIDRGYRLKLVMEQFGIKSCILNSELPVNSRQHIVDQFNKNVYQLLIATDDTEYIKEEDDEIEEGHNTENQEEKSLEGEPENDKKPSKKKKVQVKKDKEYGVSRGVDFKNVACVLNFDLPTTAKSYVHRVGRTARGGKTGTAISFVVPLKEFGKHKPSMLQTAKKDERILSRIIKQQSKLGLELQPYKFDQKQVEAFRYRMEDGFRAVTQVAIREARVKELKQELLASEKLKRHFEENPKELQSLRHDKELHPARVQQHLKRVPDYLLPESARGNGTKVKFVPFHNAKKRHSHKKGRVSKPKNGKVDPLKNFK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP9, DEAD box protein 9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RECF_STRCO
Sequence: MHVTHLSLADFRSYARVEVPLDPGVTAFVGPNGQGKTNLVEAVGYLATLGSHRVSSDAPLVRMGAERAVIRAQVRQGERQQLIELELNPGRANRARVNRSSQVKPRDVLGIVRTVLFAPEDLALVKGDPGERRRFLDELITARSPRMAGVRSDYDRVLKQRNTLLKSAALARRHGGRTMDLSTLDVWDQHLARAGAELLAQRLDLIASVQPLADKAYEQLAPGGGPVALEYKPSAPGEAHTREDLYEQLMAALAEARKQEIERGVTLVGPHRDDLLLKLGSLPAKGYASHGESWSYALALRLASFDLLRAEGNEPVLVLDDVFAELDARRRERLAELVAPGEQVLVTAAVDDDVPHVLAGARFTVAEGTVERV
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_ECO7I
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRTWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTDAAVAVSPVRSDAIKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLAQLTSLASGN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: OMPY_CHLPN
Sequence: MKTWLFFTFLFSCSSFYASCRYAEVRSIHEVAGDILYDEENFWLILDLDDTLLQGGEALSHSIWKSKAIQGLQKQGTPEQEAWEAVVPFWIEIQEMGTVQPIESAIFLLIEKIQKQGKTTFVYTERPKTAKDLTLKQLHMLNVSLEDTAPQPQAPLPKNLLYTSGILFSGDYHKGPGLDLFLEICTPLPAKIIYIDNQKENVLRIGDLCQKYGIAYFGITYKAQELHPPIYFDNIAQVQYNYSKKLLSNEAAALLLRHQMHE
What are the official names of this protein?
Putative outer membrane protein CPn_1034/CP_0818/CPj1034/CpB1074.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: ATP6_PASMU
Sequence: MAAELTTAGYIGHHLAFLKTGDSFWHVHLDTLLFSIISGAIFLFVFSKVAKKATPGVPSKMQCFVEIMVDWIDGIVKENFHGPRHAVGPLALTIFCWVFIMNAIDLIPVDFLPQLAHLFGIEYLRAVPTADISGTLGLSIGVFFLIIFYTIKSKGMSGFVKEYTLHPFNHPLLIPVNLALESVTLLAKPVSLAFRLFGNMYAGELIFILIAVMYMANNFALNSMGIFMHLAWAIFHILVITLQAFIFMMLTVVYLSMGYNKAEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MGMT_HUMAN
Sequence: MDKDCEMKRTTLDSPLGKLELSGCEQGLHEIKLLGKGTSAADAVEVPAPAAVLGGPEPLMQCTAWLNAYFHQPEAIEEFPVPALHHPVFQQESFTRQVLWKLLKVVKFGEVISYQQLAALAGNPKAARAVGGAMRGNPVPILIPCHRVVCSSGAVGNYSGGLAVKEWLLAHEGHRLGKPGLGGSSGLAGAWLKGAGATSGSPPAGRN
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: END5_BPT4
Sequence: MTRINLTLVSELADQHLMAEYRELPRVFGAVRKHVANGKRVRDFKISPTFILGAGHVTFFYDKLEFLRKRQIELIAECLKRGFNIKDTTVQDISDIPQEFRGDYIPHEASIAISQARLDEKIAQRPTWYKYYGKAIYA
What is the function of this protein?
Participates in the repair of UV-damaged DNA by excising pyrimidine dimers that are the major UV-lesions (PubMed:6254991).  DNA glycosylase activity hydrolyzes the glycosylic bond of the 5' pyrimidine of the dimer (PubMed:6254991).  This leaves apurinic/apyrimidic (AP) sites in the DNA.  These AP sites are removed by the AP lyase activity which cleaves the intrapyrimidine phosphodiester bond (PubMed:6254991).  Catalysis proceeds via a protonated imine covalent intermediate between the alpha-amino group of the N-terminal threonine residue and the C1' of the deoxyribose sugar of the 5' pyrimidine at the dimer site (PubMed:8347626) (PubMed:16916523).
What are the official names of this protein?
Endonuclease V, DNA-(apurinic or apyrimidinic site) lyase, AP lyase, T4 pyrimidine dimer glycosylase, T4-Pdg.
Protein: RS21_CYTH3
Sequence: MIVINIKENEPIDKALKRFKKKFEKTGVLKALRARSYYEKKSVRLRKEVIRASYRLKLQEAASND
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: NADK_HELAH
Sequence: MKDSHQTIGVFVRPTHHQNPLFSELTQAKEWVLRLLEDEGFESFMADDNGLKDERLIEKAYAFLCLGGDGTILGALRMMHSYNKPCFGVRMGNLGYLTAIELNELKDFLQNLKHNKIKLEEHLALEGRIEEISFYAINEIVITRKEALGILDIEACVSHTPFNTYKGDGLIIATPLGSTAYNLSAHGPIVHALNQSYVLTPLCDFSLTQRPLVLGAEFCLSFCANKDALVIIDGQATYDLKANQKLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESSSKKN
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_YERP3
Sequence: MICPVIELAQQLIKRPSLSPSDAGCQEIMIQRLAAIGFTIEPMNFGDTLNFWAWRGEGETLAFAGHTDVVPTGDESHWHSPPFEPTIRDGMLYGRGAADMKGSLAAMIVAAERFVAAHPDHKGRLAFMITSDEEAKAINGTVKVVEALMARHERLDYCLVGEPSSTDRVGDIVKNGRRGSITANLRIHGVQGHVAYPHLADNPVHRAMPALNELVATQWDEGNAFFPATSMQIANLQAGTGSNNVIPGEFYVQFNFRFSTELTDSLIKQRVAALLDRHQLDYTLEWVLSGQPFLTAKGALVDAVVNAVKHYTEITPQLLTTGGTSDGRFIALMGAQVVELGPVNATIHKVNECVSAADLQLLSRMYQKIMEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RPP29_RAT
Sequence: MKAVIYHAFSHKEAKDHDVQELGTQRAEAFVRAFLKQSIPHMSQQDCESHLQRKAVILEYFTRLKPKPRPKKKSKGLSAKQRRELRLFDIKPEQQRYSLFLPLHELWKQYIRDLCNGLKPDTQPQMIQAKLLKADLHGAVISVTKSKCPSYVGVTGILLQETKHVFKIITKEDHLKVIPKQNCVFTIEIDDFISYIYGSKFQLRASERSAKKFKAKGTIDL
What is the function of this protein?
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein subunit p29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NSA2_RAT
Sequence: MPQNEYIELHRKRYGYRLDYHEKKRKKEGREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKDDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWESPLPKVRAQGETELLKVIRTGKRKKKAWRRMVTKVCFVGDGFTRKPPKYEKFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May play a part in the quality control of pre-60S particles (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein NSA2 homolog, Protein CDK105, TGF-beta-inducible nuclear protein 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.