PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_TRIEI
Sequence: MKFFCAFIFTALIFISLEKIGQSCCPNPIVDSEQLTIFQAVILGMVQGVTECIPVSSTAHLKIIPVALGWGDPGVAFTAVIQLGSIVSIVWYFWNDLTKITFGAYKSIITSDYQSPDLKMLVSIGLGTIPIVFFGLLIKVFIPDFDNSRLRSTVAIAIASIIMALLLVIAERIGSRKRNFEKLDIRDGIVIGLAQVLALIPGVSRSGSTITGGLFIGLERSTAARFSFLLGLPAITLAGLVELKTLLDEGFGSVGLVATLTGVFSAIIFSYIAISWLMRYLQTQDTWIFIWYRLAFGILILIGIISGVIENT
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRIM5_ALOSA
Sequence: MASKILVNIKEEVTCPICLELLTEPLSLDCGHSFCQACITANHKESRERSCPLCRVSYHSENLRPNRHLANIAERLREVMLSPEEGQKVDRCARHGEKLLLFCQQHGNVICWLCERSEEHRGHRTSLVEEVAQKYREKLQAALEMMRQKEQDAEMLEADVREEQASWKIQIENDKTSTLAEFKQLRDILDCEESNELQKLEKEEENLLKRLVQSENDMVLQTQSIRVLIADLERRLQGSVMELLQGVEGVIKRIKNVTLQKPETFLNEKRRVFQAPDLKGMLQVFKELKEVQCYWAHVTLIPNHPSCTVISEDKREVRYQEQIHHHPSMEVKYFYGILGSPSITSGKHYWEVDVSNKSAWILGVCVSLKCIGNFPGIENYQPQNGYWVIGLRNADNYSAFQDAVPETENYQPKNRNRFTGLQNADNCSAFQNAFPGIQSYQPKKSHLFTGLQNLSNYNAFQNKVQYNYIDFQDDSLSTPSAPLIVPLFMTICPKRVGVFLDYEACTVSFFNVTSNGYLIYKFSNCQFSYPVFPYFSPMTCELPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2.
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: RNC_ANOFW
Sequence: MSKQRPYVKFKQFQEQTGIFFRNEKLLIQAFTHSSYVNEHRKRLHEDNERLEFLGDAVLELTVSQYLFEQFPQMSEGELTKMRAAIVCEPSLVTFAHALSFGDLVLLGKGEELTGGRMRPSLLADVFEAFIGALYLDQGIEAVVQFLGKTIFPKIREGAFSHVMDYKSQLQEFVQRDGSGVLEYKILQERGPAHNKEFVSRVSLNGEELGVGVGRSKKEAEQRAAQMALAKLKQLQQG
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_HELAH
Sequence: MLKTTQTSLFIFIGVFLLIFGTDQAIKYAILEGFRYESSIIDIVLVFNKGVAFSLLSFLEGSLKYLQILLILGLFIFLMRQIELFKAHTIEFGMVFGAGVSNILDRFVHGGVVDYVYYHYGFDFAIFNFADVMIDVGVGVLLIRQFFFKQKQNKIKA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COAD_PETMO
Sequence: MGIRDAAYPGSFDPITFGHVNIVKRSIERFDNLYVVVVNNPNKKYLFSLQERIEMVKKDLEDIPNVIVESFDGLLVNYLKEKKIYNLIRGLRAVSDYEYELQMANANHMLFPQLEIFFLMADTDFSYISSSMIKEIASYNGDVSKWVSKFVELKLKEKLLKK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_LISMF
Sequence: MLEQLQTLKNEAETQINEASDLKTLNDLRVKYLGKKGPMTEIMKQMGKLSAEERPKMGSLANEVRTALTEAISSKQQILETEAINEKLKSETIDVTLPGTAPSIGTKHLLTQVIEEMEDMFIGMGYEIAEGPEVELDYYNFEALNLPKDHPARDMQDSFYITENTLLRTQTSPVQARTMEKHDFSKGPIKVICPGKVYRRDNDDATHSHQFTQIEGLVVGENITFADLKGTLTVLAKTMFGEEREIRLRPSFFPFTEPSVEMDISCFKCGGKGCRVCKGTGWIEILGSGMVHPNVLEMSGIDSTRYSGFAFGLGPERVAMLKYAVDDIRHLYTNDLRFTKQFQSTETGEI
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_CLOBH
Sequence: MSLVPVVVEQTNRGERSYDIYSRLLKDRIIMLSEEVNDTTASLIVAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICVGMAASMGAFLLAAGAKGKRYALPNSEVMIHQPLGGFRGQATDIGIHAERILKMKKKLNTILSDRTGKPLEQVELDTERDHFLSAEEAKEYGLIDEVIDKKK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOCS3_RAT
Sequence: MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVETQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFSLPPTEPSFEVQEQPPAQALPGGTPKRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
What is the function of this protein?
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction.  SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway.  Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including IL6ST/gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors.  Binding to JAK2 inhibits its kinase activity and regulates IL6 signaling.  Suppresses fetal liver erythropoiesis.  Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells (By similarity).  Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
What are the official names of this protein?
Suppressor of cytokine signaling 3, SOCS-3, Cytokine-inducible SH2 protein 3.
Protein: YRH1_AZOVI
Sequence: DVEAGFIEFRDLLGHCRFRDCRHDREPGCALLKALDEGRIQPQRMASYRHILASLPEPEY
What are the official names of this protein?
Uncharacterized protein in rhdA 5'region, ORF1.
What is the protein family that this protein belongs to?
To E.coli YjeQ and H.influenzae HI_1714.
Protein: YBEY_ACIAC
Sequence: MALNQLSLSLQFARFPGVEAHRAALPRHAVVRWIRHALSLDAEITVRIVDAEEGQALNREYRHKDYATNVLTFDYAQEPVVMADLVLCAPVVEREAREQNKALHEHYAHLLVHGTLHAQGWDHETSAEDADEMEAYETAIMQELGFADPYAD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_ACTPJ
Sequence: MGGISIWQLLIIVAIIVLLFGTKKLRTLGTDLGESVKGFKKAMADDKSQPQDASFEKVEAKEAASTEQKAKEKEQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GSH1_ECO57
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIDKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: TRMB_STRZT
Sequence: MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVEVGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTDYFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFEYSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RLA1_POLPE
Sequence: MADSSTSELACVYSALILHDDAITAEKMNKIISAANVNVEPYWPGLFALEGKNIGDLICNVGSSGPAAGAPAAGAAGGAVEEKKEEKKAESEDESDDDMGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P1, A1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: STA1_ARATH
Sequence: MVFLSIPNGKTLSIDVNPNSTTISAFEQLAHQRSDVPQSFLRYSLRMRNPSRVFVDSKDSDSILLSDLGVSRFSTVIIHVLLLGGMQAAPPKPRLDFLNSKPPSNYVAGLGRGATGFTTRSDIGPARAAPDLPDRSALATAAAPGVGRGAGKPSEAEAEDDEEAEEKRYDENQTFDEFEGNDVGLFANAEYDEDDKEADAIWESIDQRMDSRRKDRREAKLKEEIEKYRASNPKITEQFADLKRKLHTLSADEWDSIPEIGDYSLRNKKKKFESFVPIPDTLLEKAKKEKELVMALDPKSRAAGGSETPWGQTPVTDLTAVGEGRGTVLSLKLDNLSDSVSGQTVVDPKGYLTDLKSMKRTTDEEIYDRNRARLLYKSLTQSNPKNPNGWIAAARVEEVDGKIKAARFQIQRGCEECPKNEDVWLEACRLANPEDAKGVIAKGVKLIPNSVKLWLEAAKLEHDVENKSRVLRKGLEHIPDSVRLWKAVVELANEEDARILLHRAVECCPLHLELWVALARLETYAESKKVLNKAREKLPKEPAIWITAAKLEEANGKLDEANDNTAMVGKIIDRGIKTLQREGVVIDRENWMSEAEACERVGSVATCQAIIKNTIGIGVEEEDRKRTWVADADECKKRGSIETARAIYAHALSVFLTKKSIWLKAAQLEKSHGSRESLDALLRKAVTYVPQAEVLWLMGAKEKWLAGDVPAARAILQEAYAAIPNSEEIWLAAFKLEFENKEPERARMLLAKARERGGTERVWMKSAIVERELGNVEEERRLLNEGLKQFPTFFKLWLMLGQLEERFKHLEQARKAYDTGLKHCPHCIPLWLSLADLEEKVNGLNKARAILTTARKKNPGGAELWLAAIRAELRHDNKREAEHLMSKALQDCPKSGILWAADIEMAPRPRRKTKSIDAMKKCDRDPHVTIAVAKLFWQDKKVEKARAWFERAVTVGPDIGDFWALFYKFELQHGSDEDRKEVVAKCVACEPKHGEKWQAISKAVENAHQPIEVILKRVVNALSKEENSA
What is the function of this protein?
Pre-mRNA splicing factor required for splicing and for the turnover of unstable transcripts.  May be a U5 snRNP-associated protein involved in the formation of U4/U6-U5 tri-snRNP.  Involved in responses to abiotic stresses.  Involved in microRNAs (miRNAs) biogenesis by functioning in primary miRNAs (pri-miRNAs) splicing.  Required for DNA methylation and transcriptional silencing through the RNA-directed DNA methylation (RdDM) pathway.
What are the official names of this protein?
Protein STABILIZED1, Pre-mRNA processing factor 6-like protein, Protein EMBRYO DEFECTIVE 2770.
What are the subcellular locations of this protein?
Nucleus. Nucleus, Cajal body.
Protein: Y1392_PSEPF
Sequence: MAAKVEPFWIRKTLDQLDHEEWESLCDGCGLCCLQKLEDEEDNSVYYTRIACKLLDLKTCQCSDYPNRMKFVPDCIQLTPGQAEEFKWLPPTCGYRLVSEGKDLPLWHHLVCGDRDAVHHERISQSGRMLAEGSVPEDDWEDHLIFRAG
What are the official names of this protein?
UPF0260 protein Pfl01_1392.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: SYV_XANC8
Sequence: MTQLASSYDPSSFESRLYAQWESAGHFKPSGSGEPYTVLLPPPNVTGTLHMGHAFQQTLMDALVRYHRMRGYDTLWQVGTDHAGIATEMVVSRNLALEGKGETRDTLGREGFIAKVWEWKAQSGDTIERQMRRLGTSSDWSRSTFTMDPQPSAAVTEAFVRWYEQGLIYRGQRLVNWDPVLKTAISDLEVENVEEDGFLWSIRYPLADGVTYEHVEHDADGVETLRETRDYLVVATTRPETMLGDTAVMVHPDDARYATLHAAQIVLPLTGRLVPVITDDYVDRAFGTGVVKVTPAHDFNDYQVGVRHDLPLINLFTVTAAINDNAPERYRGLDRYDARKLVLSELEDLGLLVETKPHKLQVPRGDRTGQVIEPYLTDQWFVKMDALAKRGLELVESGQVKFVPPNWINTYRHWMENIQDWCISRQLWWGHRIPAWFDEAGKCYVGHDEAQVRATHGLGAEVALHQDSDVLETWFSSQLWPFSTLGWPDAQAMDERGFARYLPSSVLVTGFDIIFFWVARMIMATDSFTGQVPFRDVYITGLIRDAQGQKMSKSKGNVLDPLDIIDGISIEDLVAKRTSGLMQPRMAEKIEKATRKEFPDGIIAHGADALRFTIAALATHGRDIKFDLGRAEGYKNFCNKLWNATRFALMNTEGAQFSGVPQPQTETERWILARLDAVAAEAQAHYANYRFDLLAQTLYEFAWNAFCDWFVELAKPALNGAVQDAADSTRHTLLYVLEALLRLLHPLTPFVTEELWQQVAPRLGITGDTISLQAFPQRGDVDTSGYAGAEADIEWLKAMVSALRRVRSELNVPPSKQVRLWLQAGSSDDRARVARFASQLAFLLKLEAIDWLAAGQEAPPAAAAIVGELTLLVPLEGLVDMDAERTRLDKEIKRVENEIGKCNGKLGNATFVQNAPAAVVEQERARLNDWTTQLTGLREQRAKL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_CHAGL
Sequence: MTTPNPNKQSVELNRTSLFWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: THIC_BURCH
Sequence: MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTEVLPGLSSQYGLERAADPATAELRFPGLHRNPRRAQPGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYIESLKSSGPNGAKLAAMMGRQHPGQAFGAAAFGANALAEITPEFVRDEIARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALKKGMEVKAVEFVKTGAEIYHRQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RL20_MYCTO
Sequence: MARVKRAVNAHKKRRSILKASRGYRGQRSRLYRKAKEQQLHSLNYAYRDRRARKGEFRKLWIARINAAARLNDITYNRLIQGLKAAGVEVDRKNLADIAISDPAAFTALVDVARAALPEDVNAPSGEAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: HYAL1_PIG
Sequence: MAAHLLPICTLFLNLLSVAQGSRDPVVLNRPFTTIWNANTQWCLKRHGVDVDVSVFEVVVNPGQTFRGPNMTIFYSSQLGTYPYYTSAGEPVFGGLPQNASLDVHLNRTFKDILAAMPESNFSGLAVIDWEAWRPRWAFNWDAKDIYRQRSRALVQKQHPDWPAPWVEAAAQDQFQEAAQTWMAGTLKLGQTLRPHGLWGFYGFPDCYNYDFQSSNYTGQCPPGVSAQNDQLGWLWGQSRALYPSIYLPSALEGTNKTQLYVQHRVNEAFRVAAAAGDPNLPVLPYAQIFHDMTNRLLSREELEHSLGESAAQGAAGVVLWVSWENTRTKESCQSIKEYVDTTLGPFILNVTSGALLCSQAVCSGHGRCVRRPSHTEALPILNPSSFSIKPTPGGGPLTLQGALSLKDRVQMAEEFQCRCYPGWRGTWCEQQGTR
What is the function of this protein?
May have a role in promoting tumor progression.  May block the TGFB1-enhanced cell growth (By similarity).
What are the official names of this protein?
Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted. Lysosome.
Protein: PEX31_ARATH
Sequence: MDLVRGLWRKHRRKILVTTTCLGSGYLLYKLYNAHTRKLADLERELANERENDEIIKTQMKAHFDNIQMIADTTTLPHAIHHLSSRVVEEIDVSSIMDKLSKGKGILIPSEKLQLWNELKILSFTRMVLSLWSVTMLSLYIRVQVNILGRHLYIDTARGLGSSHLLDELDLIERDDEQKFLTSADFLATSGMPSLISNMQNAVKEVLKGKQLKDVLTTSALRETVMRILDVFMSTGSPHHWVDYLMMSQDATTDVSSSDATVTKFHLLITETREVLTSNDFSNVAEISLKCCAVALVEEMETQTGLATGMQLAKLLPQIEKTMPEISAEPEKNRFLQLIRDLPEVKLFFTLLYANMPQ
What is the function of this protein?
Involved in morphology determination of peroxisomes, but not in import of peroxisomal matrix proteins.  May act as a docking factor for PEX19 and be necessary for the import of peroxisomal membrane proteins in the peroxisomes.
What are the official names of this protein?
Peroxisome biogenesis protein 3-1, Peroxin-3-1, AtPEX3-1.
What is the protein family that this protein belongs to?
Belongs to the peroxin-3 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: DNAJ_BURO1
Sequence: MAKRDYYEVLGVAKNASDDEIKKAYRKLAMKYHPDRNPDSKDAEEHFKEAKEAYEMLSDGQKRAAYDQYGHAGVDPNMGGAGAQGFGGFADAFGDIFGDIFGQAAGGAARGGRGGPQVYRGADLRYSMEITLEQAAHGYDTQIRVPSWVSCEVCHGSGAKPGTKPETCPTCHGQGTVRMSQGFFSIQQTCPKCHGTGTYIPEPCAHCHGSGKVKETKTLEVKIPAGIDDGMRIRSAGNGEPGINGGPPGDLYVEIHIKPHSVFERDGDDLHCQMPIPFTTAALGGEIEVPTLAGRASFPVPEGTQSGKTFRLRGKGIKGLRSSIAGDLYVHVQVETPVKLTDQQRDLLKQFEKSLAEGGARHSPQSKSWFDRVKSFFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
Protein: DPCKG_HALS3
Sequence: MSETDAAATLPADARDAFKSPIGPVYTDAAALLADATPPIIAVGDVVTYHLVDAGQTPAVAVVDGRTERDAVRPAVRDAIPEPDLTVASEPGTVSVSLVRALVDAIADADATVVSVDGEEDLAVVPAVLAAPADATVVYGQPGEGMVRVPVTDAGRAEMRERADRLETTAAFWRLVD
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: RL9_ALKEH
Sequence: MEVILLEKVANLGDLGDRVKVRPGYGRNYLVPQGKAKPATKENIRYFEERRAELERQAQEALAAAEARKEQLEGLTVTISAKSGEEGKLFGSVGTQDVADAITAAGVEVARREVRMPEGPIRVTGEYELELGLHTDVTALVKVVVQSQEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RL10_BARHE
Sequence: MNRAEKREFVTWLNEAFRKSGSVIVAHYSGLTVSQMNDLRSKMSEAGGAIKVAKNRLAKIALQGTESESIVDLFSGQTLIAYSEDPITAPKVAVDFAKTNDKFVILGGSMGATSLSVDAVKSLASLPSLNELRAKLVGMISTPATRIAQVVNAPAGQVVRVIGAYAQEGKAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CYB_OPHHA
Sequence: MSNQHILLMSNLLPVGSNISTWWNFGSMLLTCLAMQTLTGFFLAIHYTANINLAFSSVIHITRDVPYGWTMQNLHAIGASMFFICIYIHIARGIYYGSYLNKEVWLSGITLLITLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTLTTWLWGGFSINDPTLTRFFALHFILPFIIISLTSIHIILLHNEGSSNPPGTNSDIDKIPFHPYHSYKDMLMVTTMITLLFLILSFSPDLLNDPENFSKANPMITPQHIKPEWYFLFAYGILRSIPNKLGGTLALLMSIAILMTTPFTHTSYTRSMTFRPLTQILFWTLVATFITLTWTATKPVESPFIIISQMTSIFYFFFFIMNPILGWTENKIMMMND
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.