PharMolix/UniProtQA huggingface dataset:
Protein: LOLE_ECOLI
Sequence: MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVGLSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDHVQKVPGIAAAAPYINFTGLVESGANLRAIQVKGVNPQQEQRLSALPSFVQGDAWRNFKAGEQQIIIGKGVADALKVKQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMGSSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAMVLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCGVIIGVVVSLQLTPIIEWIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSLLASWYPARRASNIDPARVLSGQ
What is the function of this protein?
Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane.  Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA.
What are the official names of this protein?
Lipoprotein-releasing system transmembrane protein LolE.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KTHY_SALSV
Sequence: MGSNYIVIEGLEGAGKTTARDVVVETLEQLGIRNMIFTREPGGTQLAEKLRSLVLDIRSVGDEVITDKAEVLMFYAARVQLVETVIKPALAQGVWVIGDRHDLSTQAYQGGGRGIDQTMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGDLDRIEQESFDFFNRTRARYLELAAQDSRIRTIDATQPLDAVMRDIRATVTKWVQEQAA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: DADA_YERPG
Sequence: MRVVILGSGVVGVTSAWYLAKEGHDVTVIDRQDGPAQETSAGNAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAIRLDGSSLQLRWMWQMLRNCDTSHYMVNKSRMVRLAEYSRDCLKDLRAATGIQYEGRQGGTLQLFRTEQQFDNAAKDIAVLDDAGVPYSLLTAEQLATVEPALAKVAHKLTGGLRLPNDETGDCKLFTERLAKMAEQAGVKFIFNRSVDKLLVEGDQIAGVLCGDDIIKADAYVVAFGAYSTALLAGLVSIPVYPLKGYSLTIPITDPASAPFSTVLDETYKIAITRFDDRIRVGGMAEIVGFNTQLAPARRETLEMVVRDLYPHGGDISQAVFWSGLRPMTPDGTPIVGRTPLKNLYLNTGHGTLGWTMACGSGQLLADIIQGRRPAIVADDLSVARYRAGFQPLNIAPLHDIHPIR
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: AROL_ECO81
Sequence: MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVADIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIO_RABIT
Sequence: MVKQIESKSAFQEVLDSAGDKLVVVDFSATWCGPCKMIKPFFHALSEKFNNVVFIEVDVDDCKDIAAECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELL
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).  Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide.  Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.  Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Secreted. Note=Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA). Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus. Secreted by a leaderless secretory pathway.
Protein: LEU1_STAAR
Sequence: MSSHIQIFDTTLRDGEQTPGVNFTFDERLRIALQLEKWGVDVIEAGFPASSTGSFKSVQAIAQTLTTTAVCGLARCKKSDIDAVYEATKDAAKPVVHVFIATSPIHLEHKLKMSQEDVLASIKEHVTYAKQLFDVVQFSPEDATRTELPFLVKCVQTAVDAGATVINIPDTVGYSYHDEYAHIFKTLTESVTSSNEIIYSAHCHDDLGMAVSNSLAAIEGGARRIEGTVNGIGERAGNAALEEVALALYIRNDHYGAQTALNLEETKKTSDLISRYAGIRVPRNKAIVGQNAFSHESGIHQDGVLKHRETYEIMTPQLVGVSTTELPLGKLSGKHAFSKKLKALGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSGLQSAVVVIKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAEVHVNLLIEGKTVNGFGIDHDILQASCKAYVEAHAKFAAENVEKVGN
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: GREA_STRZJ
Sequence: MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDLSENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDEEEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MNMA_YERPG
Sequence: MSDNSQKKVIVGMSGGVDSSVSAYLLQQQGYQVAGLFMKNWEEDDDEEYCSAATDLADAQAVCDKLGMELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRQDVDGKSRLLRGLDGNKDQSYFLYTLSHEQIAQSLFPVGELEKPEVRRIAEQLDLVTAKKKDSTGICFIGERKFRDFLGRYLPAQPGPIMTVDGQLVGKHQGLMYHTLGQRKGLGIGGTKEGGDDPWYVVDKDLDSNTLLVAQGHEHPRLMSVGLVAQQLHWVDRQPVTAPFRCVVKTRYRQQDIPCTVTPLDDERVDVRFDDPVAAVTPGQSAVFYQGEICLGGGIIEQRYPLTNPA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C27_BOVIN
Sequence: MSVRFSSASRRLGSCGGAGSVRLSGGGAGFGVGSTGSVPGFGSGFTCAFGGSSSAGSYSGGLGGGSASCTAFTGNEHGLLSGNEKVTMQNLNDRLASYLDNVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFTVIDDLRNQIISATTSNANIVLQNDNARLTADDFRLKFENEQALHQSVDADVSSLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELTEMKRNLQTLEIELQSLLATKHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCRLIDGEDGSCAKSKGYGGPGHQIKDPSKATVVKTIVEEIDPRGKVLSSRVHSVEEKSTKVNNVKSEQRVPS
What is the function of this protein?
Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs).
What are the official names of this protein?
Keratin, type I cytoskeletal 27, Cytokeratin-27, CK-27, Keratin-27, K27, Type I inner root sheath-specific keratin-K25irs3.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCAL_STRPJ
Sequence: MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAIVDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRDYQKIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYAKAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQASKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRYTKARVRRLLSYILAQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDAMTQKADQIYQLGNLSIAQQNFGRVPIRIETN
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_TRIV2
Sequence: MASTIQALPQEVVYLITAGEVIDSFAAVVRELVENSLDAGANRIVVYLWPQQWRVRVADNGCGMNLDDLQQAASAHSTSKIRSSADLWKIHSLGFRGEALHSLTTLADVEIISRAPENVGWRVVYGDNGEATQVEATAIAPGTVVTVSNLFASCAARRQGLPTTAQQMKAVQATIQQIALCHPQTTWQVWQNDRIWFTISPAATAGQLIPQFLPQLRPGDLQEIKLEIPNPENPQLSTNNKANATTLSLVVGLPDRCHRHRPDWVRVAINGRMIKSPELEQTILAAFHRTLPRDRYPLCFLHLLISPDQINWNRNPAKTEIYLHDLSYWQEQVTQAINQTLRISAANIKESVQTTRVSQLLKAAEEKGNYNFNPQNANPADNTQHYLKAVAQVSNTYIVAEHSGGMWLVEQHIAHERVLYEQLCDNWRLIPVEPPIILYQLSPAQVAQLQRIGLDIDIFGEQLWAVRNLPAMLQQREDCAEAILELSWGGDLQTAQVAVACRSAIRNGTPMSLPEMQKLLDDWQRTRNPRTCPHGRPIYLSLDESSLSRFFRRHWVIGKSHGI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: HD4_ENCCU
Sequence: MKDPRWIMEGEAMAGLVKLRRLSDKSYLGLSGYRYKTHIQVYVLTKIFEITQYPSHDTRQNLAILLNMSPRTIQIWFQNSRSVSRGAAKKKVSKDNGPQEAPKAKIVSNLTVPVKYITWLILSYPSYSQIGN
What are the official names of this protein?
Homeobox protein HD-4, EcHD-4.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL13_BURCM
Sequence: MKTFSAKAHEVTREWYVIDATDKVLGRVASEVARRLRGKHKPEFTPHVDTGDFIIIINASKLKVTGNKTLDKKYYRHSGYPGGIYETTFGKMQERFPGRALEKAVKGMLPKGPLGYAMIKKLKVYAEATHPHSAQQPKALEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: UPP_SHESR
Sequence: MKVVEVKHPLVRHKIGLMREGDISTKRFRELAAEVGSLLTYEATADFETETVTIEGWNGPVDVDQIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFEKLASDMNERIALIVDPMLATGGSMIATIDLLKKRGCTSIKALVLVAAPEGIKALEAAHPDVELYTAAIDRCLNEKGYILPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: PGK_STRP6
Sequence: MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEEAINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAFAGYTEVRDTEGEAVSEGFLGLDIGPKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSEA_MYCS2
Sequence: MADPGHVFRRAFSWLPSQFASQSDAPVGAPRQFGSTEHLSVEAIAAFVDGELRMSAHLRAAHHLSLCPECAAEVDAQSQARTALRESCPIAIPNSLLGMLSQIPHRTPEVTPDVSEQAKFADDPTRGRRKRR
What is the function of this protein?
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigE.  ECF sigma factors are held in an inactive form by an anti-sigma factor (By similarity).
What are the official names of this protein?
Anti-sigma-E factor RseA, Regulator of SigE, Sigma-E anti-sigma factor RseA.
What is the protein family that this protein belongs to?
Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACD_STAAR
Sequence: MSKSNQKIASIEQLSNNEGIISALAFDQRGALKRMMAKHQTEEPTVAQIEQLKVLVAEELTQYASSILLDPEYGLPASDARNKDCGLLLAYEKTGYDVNAKGRLPDCLVEWSAKRLKEQGANAVKFLLYYDVDDAEEINIQKKAYIERIGSECVAEDIPFFLEVLTYDDNIPDNGSVEFAKVKPRKVNEAMKLFSEPRFNVDVLKVEVPVNMKYVEGFAEGEVVYTKEEAAQHFKDQDASTHLPYIYLSAGVSAELFQETLKFAHEAGAKFNGVLCGRATWSGAVQVYIEQGEDAAREWLRTTGFKNIDDLNKVLKDTATSWKQRK
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase, D-tagatose-1,6-bisphosphate aldolase, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: RS12_DESAL
Sequence: MPTINQLVRHGRKRSVKKTNTPALKASPQKRGVCTRVYTTTPKKPNSALRKVARVRLTTGMEVTAYIPGVGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDSIGVQDRKQGRSHYGAKKPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: GDLO_DROME
Sequence: MWAAKLIVVTLLLLQFAALALSCSCGEEAKLECGCTKHH
What are the official names of this protein?
Gonadal protein gdl-ORF39.
Protein: URP2_MOUSE
Sequence: MAGMKTASGDYIDSSWELRVFVGEEDPEAQSVTLRVTGESHIGGVLLKIVEEINRKQDWSDHAIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRVLRLRASFSKPLFQTVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEEVHDLTKVVLAGGVAPTLFRGMPAHFSDSAQTEACYHMLSRPQPAPDPLLLQRLPRPSSLPDKTQLHSRWLDSSRCLMQQGIKAGDVLWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLTEEIDCTEEEMMVFAALQYHINKLTLSGDVGELASGDLGLDDLDAALNNLEVKLKGSAPSDMLDSLTTIPELKDHLRIFRPRKLTLKGYRQYWVVFKDTTLSYYKSQDEAPGDPTQQLNLKGCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYAQWMAACRLASKGRTMADSSYASEVQAILAFLSLQRAGGSNGGSGNKPQGPEAPAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLTEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQLTGGHEAF
What is the function of this protein?
Plays a central role in cell adhesion in hematopoietic cells (By similarity).  Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (PubMed:18278053).  Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234461).  Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (PubMed:18278053).
What are the official names of this protein?
Fermitin family homolog 3, Kindlin-3, Unc-112-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the kindlin family.
What are the subcellular locations of this protein?
Cell projection, podosome. Note=Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells.
Protein: TAL_STREM
Sequence: MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIKEICEIVDGPISAEVTGLTAEEMIAEARSIAKWHDNVVVKIPMTTEGLKATNVLSQEGIKTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEIIAASIRTAAHVEAVAQLGAHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_SHEPA
Sequence: MAKQIQAIRGMNDILPTQSPLWQKLETVLRDTVGSYGYSEIRTPIVESTDLFKRSIGEVTDIVEKEMYTFEDRNGDSLTLRPEGTASTVRAGNEHGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQFGVEVYGIPTADIDAEVLMLSAKLWEKLGITEHVTLELNTLGDTEERAAYRDALIAFLEQHKEVLDEDSQRRMYSNPLRVLDSKNADVQALLADAPVLMDYFGEDTRSHFSHLCELLEAVGIQYTINPRLVRGLDYYNRTVFEWVTSSLGSQGTVLAGGRYDGLVGQLGGKPTPAVGFAMGLERIVLLLQTLELDKDIGPAVDVYVTAMGDNCKVEAIKIAQELRASLPTAKVMSHCGGGNFKKQMKRADKSGACVALVIGEDELANNQVAVKHLREDKAQELVARDALATYIAELI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_RICAE
Sequence: MLELFFEYIFPLIIIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQPIADAVKLLFKEPIIPTNSDKILFILAPMITFILSLIGWAVIPFAKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEVSMGLVIITVLLTTGTLNLSEIIEVQRTMPWWIDLMLLPMGVVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALFFLGEYANMILVSAMTTTFFLGGYLPPFNISWLDCIPGFFWFVFKVGFLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTLFWVVLVSSVLVYTDNLPSI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y384_RICTY
Sequence: MKKFIFCFLYLYTLNIFAVSKIAHNKLNSCSITRNIFNNYEPKVFETTNNLLRKTGRLSKFYGEMILIRGKILDQNCVPVTDAKVYLWQAGSGGKYPYEPLKTRVDKRRFTNKSDSSFTGSGIVTTNNKGEYYFISMLPYKSSHYLRTANIRIEHPNLTTLETRLELSDQNMCDNDCGEISPILTETKKNIQSYCFDLVLQGTTLKRY
What are the official names of this protein?
Putative dioxygenase RT0384.
What is the protein family that this protein belongs to?
Belongs to the intradiol ring-cleavage dioxygenase family.
Protein: CYSD2_ALKEH
Sequence: MDNRTLTHLRQLEAESIHIIREVVAEFENPVMLYSIGKDSSVMLHLARKAFYPGTPPFPLMHVDTTWKFREMIEFRDRMAKEAGMELIVHINQEGVAQGIGPFSHGSRVHTDVMKTQSLKQALDKYRFDAAFGGARRDEERSRAKERVYSFRDRNHAWDPKNQRPELWRLYNGQVHKGESIRVFPLSNWTELDIWQYIYLEEIPIVPLYYAARRPVVERDGTLIMVDDDRMPLEPGEEPEMAMVRFRTLGCYPLTGAIRSEAATLPEIIQEMLLTKSSERQGRVIDHDAAGSMEEKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2 2, ATP-sulfurylase small subunit 2, Sulfate adenylate transferase 2, SAT 2.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RISB_CHLTB
Sequence: MKPLKGCPVAKDVRVAIVGSCFNSPIADRLVAGAQETFFDFGGDPSSLTIVRVPGAFEIPCAIKKLLSTSGQFHAVVACGVLIQGETSHYEHIADSVAAGVSRLSLDFCLPITFSVITAPNMEAAWERAGIKGPNLGASGMKTALEMASLFSLIGKE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PIMA_MYCBO
Sequence: MRIGMICPYSFDVPGGVQSHVLQLAEVMRTRGHLVSVLAPASPHAALPDYFVSGGRAVPIPYNGSVARLRFGPATHRKVKKWLAHGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKSLTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVDSFASAARLDGYPRQGKTVLFLGRYDEPRKGMAVLLDALPKVVQRFPDVQLLIVGHGDADQLRGQAGRLAAHLRFLGQVDDAGKASAMRSADVYCAPNTGGESFGIVLVEAMAAGTAVVASDLDAFRRVLRDGEVGHLVPVDPPDLQAAALADGLIAVLENDVLRERYVAAGNAAVRRYDWSVVASQIMRVYETVAGSGAKVQVAS
What is the function of this protein?
Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM).  Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1).
What are the official names of this protein?
Phosphatidyl-myo-inositol mannosyltransferase, Alpha-mannosyltransferase, GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase, Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase, Phosphatidylinositol alpha-mannosyltransferase, PI alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FLIW_CALBD
Sequence: MVVQKSVVKSRVFGELEVSEENIIFFEEGIPAFENLKKFVIVKEDQSPFYWLQSVEDKDIAFVIINPFEIKPDYEFDLPDEVVNKLEITSAQDVAVFCIVVIPEDVKQTRVNLKAPIIINVHKRKGIQYLLDDERYPLRYYLFENLNSDEQK
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOVO_CHRRI
Sequence: IATVDCSDYPKPACSLDYMPLCGSDSKTYSNKCNFCNAVVDSNGTLTLSHFEKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: STPG1_RAT
Sequence: MSQKFANTGSFIEREDLGKPNKGVDRVQKGFTAAYPTQSSIPYRHRRSVIPESEKRGFNSQARRFYSKKDDIPGPGFYNVIHQSLVFNSVSLSKRGTCTFPSTCARLGPIISKYPAANAYTIRSELASKKDFSNSCSSMFQLPTFIKVVKSETPAPNHYNASISICKQRNNVCARAGFLSKTPRGFVPSSEPGGPAPGHYDVNESLVRESPKVLVSCFKSKTGRGLKPTSTGPGPGYYNPNDQTKILRKSHLPKTTLLNFSAQPLPLPEKPPLPGPGQYEIVNYQGPPKHFISTASFVSNTSRWPVKSSKPTLPGPASYKPEIPGKQSFLYNEDNKWIPAV
What is the function of this protein?
May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.
What are the official names of this protein?
O(6)-methylguanine-induced apoptosis 2, MAPO2, Sperm-tail PG-rich repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the STPG1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.