PharMolix/UniProtQA huggingface dataset:
Protein: FLOT2_ORYSJ
Sequence: MARFVVAGPSEYLAITGWGIDDVKLAKKAWVFAGQKCSRFDISPVNYEFNVEAMSSEKLAFNLPAVFTIGPKITPAPAPEVDGASNQRRVLMPESEEKLLLYAKLIAPHDHASNHVKQLVKGVIEGETRVLAASMTMEEIFQGTKKFKQEVFDQVQLDLNKFGLYIYNANVKQLVDEPGHEYFSYLGKKTQQEAANKAKVDVAEERMKGEVGAKEREGLTRQNAAKVDAETKVVSVRQQGIGLREEAKVKAEVQVYENEREAEIAAAQAGLAMKKAGWEKQSKVAQVEAVKAVAIREAELQMEVERKNALRLTEKLKAEQLSKATVQYETQVQESNAALYNRQKAADATLYEQVKSAEARKAQADAMFFEQKLAEDARLYAKQKEAEALAMVGKAKVEYVTSMLQALGGDYGALRDYLMIDGGMYQEMARVNASAVSGMQPKISIWSGADGAAGEAGAGAMQQVAGVYKMLPPLLSTVHEQTGMQPPAWMGSLPKDGAN
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
What are the official names of this protein?
Flotillin-like protein 2, Nodulin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane, caveola.
Protein: SYM_RHILO
Sequence: MSREKYYLTTPIFYPNGKPHIGHAYTVIATDALARFQRLDGKDVFFLTGTDEHGLKMQQTAEKEGITPQALADRNSAIFRSMTEAVGGSNDEYIRTTEPRHYASCQAIWKAMAANGDIYLDRYSGWYSVRQEAYFDESETTLGEDGVRREPLGSPVEWNEEESYFFRLSAYQDKLLALYESQPDFVGPAERRNEVMSFVKSGLKDLSISRTTFKWGVPVPGDDKHVMYVWVDALTNYITAAGYPDTKSDQWRYWPATHIIGKDIVRFHAVYWPAFLMSAGIELPKRVFAHGFLFNRGEKMSKSVGNVVDPFALIEHYGLDQVRYFFLREVPFGQDGSYSHDAIVNRTNADLANGLGNLAQRSLSMIAKNCGGVVPKRGEMTDADSAILDQAVAALTTARKAMAGQGIHLALAAIFDVVAEADRYFAGQAPWALKKTDPERMETVLWTTAELVRRVAVLCQPFIPGSAAKLLDLLAVPADKRDFVHVHADYALVPGTALPAPEGVFPRYVEQPGANA
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_ECOL5
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVLMPVVQPSELWQESGRWEQYGPELLRIADRGDRPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAF1B_XENLA
Sequence: MEAEDGRGYNVPCPQCSEINWAISDEGRYYCMSCHTIIEKTREVEDSEVFVNLGKIQYISRGLRKKRKQEKGWEWYVCEGFQFILIKQAESLQALGVAPQIKDEIICTFWRRYLQKTNQAYVKRPVYRNTLNLRESDSSATELDSETDEFSDGITTDASDRLSVATEDIASGSESAVSIQSGSVDGVSHTKMSKNWKPWNYVKMSMPMTLAFCYLALLWLRASITLSDLLRFVFEKRIPYFNAHQYLPEEIKLYGQDVRIFRMQSFPVYNDILNKAYELGHYLDLPRFPEIIKNCYLHPNVLCMKYLMEANLPDELHHWTCQVAEKTGTDDLHLLTFDPACKKARHIRYDVQAVALIIVVLKLLFALDDNTEWQLSTFAERMNQRDKEKPIFEFQSWYQTVRSCYEKAQQALEEEYGRFTWKSDCLLYYSHTSKAVLQKRKQMSENLHRQFSKLAGAAPDTGKQGPSSFLFKWDEQNTDRICFHGHSLEAILQQGDKPATAINTHYWLNSLKKCKSRICQHSELYEQSNFPRSYHFIVSLFAFLLRVEHCVVHHEVCLIEETFFQEFQGKKNKQKQKPRKQN
What is the function of this protein?
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription.  Binds rDNA promoters and plays a role in Pol I recruitment (By similarity).
What are the official names of this protein?
TATA box-binding protein-associated factor RNA polymerase I subunit B, RNA polymerase I-specific TBP-associated factor 63 kDa, TAFI63, TATA box-binding protein-associated factor 1B, TBP-associated factor 1B.
What is the protein family that this protein belongs to?
Belongs to the RRN7/TAF1B family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RS11_FRAAA
Sequence: MPPKTRAAGAKKVRRKEKKNVAHGHAHIKSTFNNTIVSITDPTGNVISWASAGHVGFKGSRKSTPFAAQMAAENAARKAQEHGMRKVDVFVKGPGSGRETAIRSLQAAGLEVGAIQDVTPTPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MPZL2_PONAB
Sequence: MYGKSSTRAVLLLGIQLTAIWPIAAVEIYTSRVLEAVNGTDARLKCTFSSFAPVGDALTVTWNFRPLDGGPEQFVFYYHIDPFQPMSGRFKDRVSWDGNPERYDASIFLWKLQFDDNGTYTCQVKNPPDVDGVIGEIRLSVVHTVRFSEIHFLALAIGSACALMIIIVIVVVLFQHYRKKRWAERAHKVVEIKSKEEERLNQEKKVSVYLEDTD
What is the function of this protein?
Mediates homophilic cell-cell adhesion.
What are the official names of this protein?
Myelin protein zero-like protein 2, Epithelial V-like antigen 1.
What is the protein family that this protein belongs to?
Belongs to the myelin P0 protein family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PUR2_ECO57
Sequence: MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPTLQNVAIGVTDIPALLDFAQNEKVDLTIVGPEAPLVKGVVDTFRAAGMKIFGPTAGAAQLEGSKAFTKDFLARHNIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMTLEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRVGDKDTGPNTGGMGAYSPAPVVTDDVHQRTMERIIWPTVKGMASEGNTYTGFLYAGLMIDKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACEGKLDEKTSEWDERASLGVVMAAGGYPGDYRTGDVIHGLPLEEVEDGKVFHAGTKLADDEQVVTSGGRVLCVTALGHTVAEAQKRAYALMTDIHWDDCFCRKDIGWRAIEREQN
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: RLA2A_MAIZE
Sequence: MKFVAAYLLAVLAGNASPSADDLTAILESVGCEVDNEKMELLLSQLSGKDITELIAAGREKFASVPCGGGGVAVAAAAPAAGGAAPAAEAKKEEKVEEKEESDDDMGFSLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2A, P2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: OBG_HAEDU
Sequence: MKFIDEALIRVEAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVYLIADENLNTLIDYRFEKRYAAGRGENGRSAGCTGHRGNDITLRVPVGTRAIDNDTKEVIGDLTQHGMKMLVAKGGYHGLGNTRFKSSVNRAPRQKTNGTAGEKRDLLLELMLLADVGMLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPSLGVARVGSDRSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLIHLVDIMPIDESDPVQNITVIESELYQYSEKLADKPTWLVFNKIDTIGEEIAAEQAKNIAEQIGWQGDYYLISAATGQNVQQLTRDIMDFIEANPRQIIEENKALDEVKFKWDDYHQQAMQHPVEEDWSDFDDEWSEEDEEGVEIIYERG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAL7_CRYNJ
Sequence: MTATHTHSNGSNDFTPVSINDHVHRRFNPLLGKHVLVSPHRSLRPWNGQKETPAIPVETPHDSKCYLCPGNKRTTGQHNPDYKGIYVFENDFPALLPDPLAVGTNKISDDPLFQSEPVRGRCKVICFHPRHDLTMAAMRISEINHVLDGWKDVYAEEGKIMQEESSDGCVQIFENRGAMMGCSAPHPHGQVWTTSFVPDEPATEIENFVRYASGRSGSHMLLDYALREVKARERVVTLHESGWVAVVPYWAAWPFEILLMPYKRHIPSILQLTAEEQTGLATILKDVLSRYDNLFSCPFPYSMGLHQSPLPPTDPTSNSAQVHFHFYPPLLRSATVRKFMVGFELLGEAQRDIVPEQAAVRLRESLPHKRATLSNDKPYNP
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Protein: EFMT4_HUMAN
Sequence: MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPHFRTRHYAQAYYGWSLRHATYGSGFHFHLYLMHKGGKLSVAQLALGAQILSPPRPPTSPCFLQDSDHEDFLSAIQL
What is the function of this protein?
Protein-lysine methyltransferase that efficiently catalyzes three successive methylations on 'Lys-36' in eukaryotic translation elongation factor 1 alpha (EEF1A1 or EEF1A2).
What are the official names of this protein?
EEF1A lysine methyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: RECA_GEOSL
Sequence: MTQEREKAIELALSQIEKQFGKGAIMRLGADEALPDVAAIPTGSLSLDLALGVGGVPRGRIIEIYGPESSGKTTLALHIAAEAQKMGGIAAFVDAEHALDIGYARKLGVKTDDLLVSQPDTGEQALEIAEMLVRSGAVDVLVIDSVAALVPKAEIEGEMGDSHMGLQARLMSQALRKLTGIISKSNCCVIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRKIASLKQGQDVIGSRTKVKVVKNKVAPPFKEVEFDIYYGEGISREGDILDLAVEKGIVDKSGAWFSYGGDRIGQGRENSRLFLKERPELVNEIEGKVYDVAGIPRKGAKEAA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTL1_ARATH
Sequence: MNINCSPLGFLISLFFIVTFLAPQVKSRAFFVFGDSLVDNGNNDYLVTTARADNYPYGIDYPTRRPTGRFSNGLNIPDIISEAIGMPSTLPYLSPHLTGENLLVGANFASAGIGILNDTGIQFVNIIRISKQMEYFEQYQLRVSALIGPEATQQLVNQALVLITLGGNDFVNNYYLIPFSARSRQYALPDYVVYLISEYGKILRKLYELGARRVLVTGTGAMGCAPAELAQHSRNGECYGALQTAAALFNPQLVDLIASVNAEIGQDVFVAANAYQMNMDYLSNPEQFGFVTSKVACCGQGPYNGIGLCTPVSNLCPNRDLYAFWDAFHPTEKANRIIVNQILTGSSKYMHPMNLSTAMLLDSSKI
What is the function of this protein?
Involved in the mechanisms of salt tolerance (PubMed:16930315).  Mediates resistance to LiCl and NaCl (PubMed:16930315).
What are the official names of this protein?
GDSL esterase/lipase LTL1, Extracellular lipase LTL1, Lithium-tolerant lipase 1, AtLTL1, Li-tolerant lipase 1.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRC_SULSY
Sequence: MILIKNGHIVDPQNNLNDKFDILIEKGEIKKIEKNIQPFAGCEVIDAEGKIITPSFTDIHVHFRDPGQTYKEDIESGSKAAVAGGYTTVVCMPNTIPAIDDVPIVRYIIEKGEEIGLCRVLPSAAITKGRKGKELTEMALLKDAGAVYFTDDGAPVMDSFIMRKAMEYAGSLGTFVADHCEDLNLSQNGVAHEGEIAAALGLPPLPPEAEDTMVARDCILSIQTGMPVHICHISTKLSVEIVAWAKAMGAKVTAEVTPHHLYLTDEEFLDFSCIAKVSPPLRTHEDIEATRWALASGIIDFVATDHAPHAHYEKMQELQACPPGMLGLQFALPIVLELVKKDYFDLNRMVEVMSIQPAKKIGLKPPQIKEGEIAELTIFDPFETWEVNKETILSKSKNTPLLGRKLTGKVKYTFFKGKIVYRD
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: THII_MYCS5
Sequence: MYKKILIRYGELVLKGKNRTTFIKQLGSNIKEILNTEYEMEFDRMYIPYSEENLKNLKYVFGISSFSPVIETNKNLEDIQSAITKLINKNASTFKIAARRNDKSFELNSDQLNNLLGGFVLKNSHLKVNVKNPDQIFNIEIRKNSVYVFDKSINGIGGIPVGISGKVLHLISGGFDSPVAAYLLMKRGFKVDFLTFVTPPQTDETTIDKIKNLTKVLSRYQKESNLYVCDFSLISSYIEFTEFKSFKIILMRRSFYRIASELAKQNEILMISNGENLAQVASQTNESMAVIGSSIKNEILRPLLTYDKNEIINLSKVIETHDISILKSKEACELFAPKNPVTKPTEAKTLRIESKLDELKTYEEIVLNQKMKKFAI
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_I76A0
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILEEESDEALKMTIASVPASRYLTDMTLEEMSRDWFMLMPKQKVAGSLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSNEDGRPPLPPKQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: DLTS_STRA3
Sequence: MFSDLRKKFVFLTMSILIVVVLFLFAVSNRYNQYWDEYDAYRIVKLVAKNDYLGIPGDEPIALVTIDNQKMVKIQSNNTDLTNDVIEKSSLKLLEQGKKSRKWKSFIYSIKEYKDKTYTIAIMDLASYEVPYARRFLILVFTIFGFCLLAAVSLYLSRFIVGPVETEMTREKQFVSDASHELKTPIAAIRANVQVLEQQIPGNRYLDHVVSETKRMEFLIEDLLNLSRLDEKRSKVNFKKLNLSVLCQEVLLTYESLAYEEEKCLNDTIEDDVWIVGEESQIKQILIILLDNAIRHSLSKSEIQFSLKQARRKAILTISNPSAIYSKEVMDNLFERFYQAKDDHADSLSFGLGLSIAKAIVERHKGRIRAYQEKDQLRLEVQLPIDGFWTNTMIN
What is the function of this protein?
Member of the two-component regulatory system DltS/DltR.  Regulates the expression of the dlt operon.  Probably phosphorylates DltR.
What are the official names of this protein?
Sensor protein DltS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ANMK_PROMA
Sequence: MYVLGLMSGTSADGVDAVLVDFRGNLNKPRWKLLNSVSLKYSVDLQKAIIDAGQGSKLSGCDWLELSEAITEAHFSAASRCDPDGISTVVGCHGQTVCHRPPKPSFRGASWQLIQAPLLATLLGKNVIYDFRSKDLALGGQGAPLAPFLDYALIGRGKTWRGVLNLGGIANLSLIPPLKGPHRKCHLLGWDCGPANTLIDLAVQKITNGQMNFDCDGLMASKGKPDLDAIKKWLKEDFFQQPPPKSTGREYFGSLDLAKRFSEINSANVNDLVATITCFTACVVAQDLNNLFKKSWIKPAELFVAGGGSRNIFLMKEITNRSPGIRVLSTEKIGIPSQSREAMAFALLAWWNINQKPINTNVTGLKEPSVLGIAVRP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: HXADA_DANRE
Sequence: MTTSLLLRPRWIDPVMFLYDNGGGLDDTSKNMEGFTGGNFSPSPCRNLMSHPASLAPSATYPSSEVAAAAAGDSGKQCSPCSAVQGSASASISYGYFGGGGYYPCRMSHHHGSGGGVKTCAQSPASGSPYGEKYMDTSASTGEDYTSSRAKEFALYSSYASSPYQPVPSYLDVPVVQAISGPSEPRHESLLPMESYQPWAITTSGWNGQVYCTKEQQQTGNVWKSSIPESVSHGGADGSSFRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISAQTNLSERQVTIWFQNRRVKEKKVVNKLKSSS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A13a.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSRP_NOCSJ
Sequence: MAKEQGRKLIAQNKKARHDYHIEDTYEAGLVLQGTEVKSLRQGRASLVDGFVDIDRGEAWLHGVHIPEYSQGTWTNHAARRKRKLLLNRDEIDKIERRVNEKGLTVVPLALYFKDGRAKVEIALAKGKKSWDKRAALAERQANRETEQAVGRRLKGMHD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ILVD_LEPBL
Sequence: MSDILKKRSSMTTDGDNRAPNRAMLRAVGFTDEDFHKPMIGIASTWSEVTPCNIHINKLAEKVKEGVRTAGGVPQIYGTITVSDGITMGHEGMHFSLPSREVIADSIEIVSNAMRHDGVIAIGGCDKNMPGCLMALCRIDAPSIFVYGGTILPGHCDGQDVDIVSIFEAVGKFNAGKISREEFIRIEQNACPGAGSCGGMYTANTMSSAIEALGMSLPGSASMPAVSSRKSEDCYEAGKALINLIQKGVTPKRILTKKAFENAITVVLVLGGSTNAVLHLIAIAKEIGVDLTLEDFDRISKKTPHLADLKPGGRYAMTDLDKVGGVHGVMKYLLKEGMLHGDCLTVTGKTIAENLMDMPDLVPNQTIVRKKSEALHPSGPLVILKGNLAPEGAVAKISGLKKISITGPAKVFESEDDCFNAIMTDQIKPGDVIIIRYEGPKGGPGMREMLAVTSALVGKGLGEDVGLMTDGRFSGGTHGLVVGHISPEAFDGGPIAIVQNGDAVTIDSGKNLLQVEISQEEIQKRLKNWKPIEPRYKSGVLAKYAKLVQSATNGAITNLL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: NAGZ_XANOM
Sequence: MLLIGVAGTELSAQERDWLQHDAVAGVVLFKRNFGSRSQVVELSAAIRAAAPRPVLICVDQEGGRVQRFREGFSALAPLQSFGAQYAQAPEAALAAARAHAQLMASEVRASGVDLSFAPVVDLGRGNRAIGDRAFSDDPQIVATFTRAYVQALHGAGMAATLKHFPGHGTVLEDTHVDHASDPRPLEALQAEDLVPFVAGIEAGADAVMMAHVVYPQVAPEPAGYSQRWIEQILRGQMGFRGVVFSDDIGMAASFSAGGVAGRVHAHLDAGCDVVLVCHPELVAESLQAVQGRRLNTAALIGLIGRGALGWDGLLAGTDVSFTTPHSAHFGTTA
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_PELPB
Sequence: MPLHKSAEKRLRQSERRNARNRSRKKELKVLVKTMQKLIDTSAEKAVVEVAYRSAVQKLDRLGVKNYIHANKASRKKSQLTRLMNSYVKAD
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RNZ_BACAA
Sequence: MEFVFLGTGAGVPSKGRNVSAIALQLLEERGQTWLFDCGEATQHQILHTSVRPRRIEKIFITHLHGDHIFGLPGLLGSRSFQGGTTPLTVYGPKGIKQFIEVALSVSTTHVKYPLEIVEITEEGTVFEDNEFHVETKRLSHGIECFGYRIIEKDIQGALLVDKLLEIGVKPGPLFKRLKDGEVVELENGTILNGNDFIGPPQKGRVITILGDTRYCEASRELAQDADVLVHEATFAAEDEQQAYDYFHSTSKQAASIALQANAKRLILTHISSRYQGDTYKELLKEARELFSNTEIATDLKSFPVDR
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: HYDB_THEMA
Sequence: MFKNAKEFVQYANKLKTLREKKLNGVSIYVCVGTGCTAKGALKVYSAFEEELKKRNLLGQVTLEKIDDDKVTLNRTGCCGRCSSGPLVKIMPYRFFYSNVAPEDVPEIVDRTVLKGEPIERLFLTDPLTGEKVPRIEDTTLFKNQDFYIMEAIGESECDSIEDYIARSGYESLVKALTSMTPEEIIETVKASGLRGRGGGGFPTGLKWEFTRKAQGDIKFVVCNGDEGDPGAFMNRTLLERDPHLVLEGMIIAGYAVGAQKGYAYIRAEYPFAVKMFKKAIEDARKLGLLGENILGTGFSFDLEVKEGAGAFVCGEETALLASIEGKRGMPRPKPPFPAQSGLWGKPTLINNVETYANIPRILRDGVENYRKRGTENSPGTKMFSVAGPLKATGIIEVEFGTTLRDIIYNICGGFVEGEEFKAVQIGGPSGACLSEDFIDMPLDYDTLKKADAMVGSGGIVVITKKTCMVEVARFFLDFTKRESCGKCVPCREGTMQAYNILEKFTHGKATYEDLKTLEHLSKTIKTASLCGLGKTAPNPILSTLKLFREEYIAHIEGECPSGMCTAFKKYVINPDICKGCGLCARSCPQNAITGERGKPYTIDQEKCVKCGLCASKCPFKAIELV
What is the function of this protein?
Catalyzes the oxidation of the physiological electron carriers NADH and reduced ferredoxin, coupled to the production of H(2) (PubMed:19411328).  Acts as a bifurcating [FeFe] hydrogenase, which uses the exergonic oxidation of reduced ferredoxin to drive the unfavorable oxidation of NADH to produce H(2) (PubMed:19411328).  The beta subunit contains flavin- and NAD-binding sites and is potentially the site for NADH oxidation, with the subsequent shuttling of electrons to the alpha subunit (PubMed:19411328).
What are the official names of this protein?
Bifurcating [FeFe] hydrogenase beta subunit, Hydrogenase (NAD(+), ferredoxin) beta subunit, Iron-hydrogenase beta subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.