PharMolix/UniProtQA huggingface dataset:
Protein: LPXH_ECOK1
Sequence: MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YQHA_SHIB3
Sequence: MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPNIFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS6_TRIL1
Sequence: MLTRRIIPCLDVTGGRVVKGVQFLELRDAGDPVEIAEAYDLQGADELTFLDITASSDGRDTMVDVVRHTAERVFMPLTVGGGIRVVEDIRRMLNAGADKVSINTAAVSRPEFVNEAAERFGSQCTVVAIDARQVPGEQRWEVYTHGGRKPTGIDAVEWAVRMESYGAGEILLTSMDRDGTKDGYDLALTRAVVDAVSIPVIASGGVGNLEHLYDGFTTAGASACLAASIFHFRQHTVQEAKQYLQGRGVPIRMV
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_CUPPJ
Sequence: MADIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAEQKSWIQNVPYMDRLDYVSMMSNEHAYVMAIERLLGIEVPIRAQYIRVMFDEITRLLNHLMWIGAHALDVGAMAVFLYAFREREDMFDMYEAVSGARMHAAYYRPGGVYRDLPDTMPQYRASKVHNERAIKVMNEARSGSLLDFIEDFTNRFPKYVDEYETLLTDNRIWKQRLVDIGVVSPERALQMGFTGPMLRGSGIAWDLRKKQPYEVYDKMDFDVPVGVGGDCYARYLVRVEEMRQSNRIIKQCIEWLRRNPGPVITDNHKVAPPSRVDMKSNMEELIHHFKLFTEGMHVPEGEAYAAVEHPKGEFGIYAISDGANKPYRLKIRAPGFPHLAALDEMAKGHMIADAVTIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MATK_PHLPR
Sequence: MEKFEGYSEKHKSRQQYFVYPLLFQEYIYAFAHDYGLNDSEPVEIVSYNNKKFSSLLVKRLIIRMYQQNFGINSVNHPNQDRLLDYKIGFYSEFYSQILSEGFAIVVEIPFSLRELPCPKQKEIPKFQNLRSIHSIFPFLEDKFLHLDYLSHIEIPYPIHLEILVQLLQYRIQDVPSLHLLRFFLNYYSNWNSFITSMKSFFLFKKENKRLFRFLYNSYVSEYEFFLLFLRKQSSCLPLASSGTFLERIHFSRKMEHFGIMYPGFFRKTLWFFMDPLMHYARYQGKAIFASKGTLFFNKKWKWYLIHLWQYFFSFWTQPRRIHLNQLANSCFDFMGYLSSVPKSPLLVRNQMLENSFLIDTRMQKLDTIVPVTALIGYLSKAQFCTGSGHPISKPIWTDLSDWDILDRFGRICRNLFHYHSGSSKKQTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSAFLEEFFTEEELVFSLMFTKTTLFSFRGSHSERIWYFDIIRINDLVKPLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RHEB_DICDI
Sequence: MAPQKHRKICVMGSRAVGKSTITMQFVESHCPDSYHPTIENTYQKIIRHQGQEYSVEIIDTAGQDEYSILQKQYSIGIHGYILVYSVTSVSSLEVIKVLNDKILSSLGAEKIPRVLVGNKSDLDNERNISRDQGIQLANEWECAFVECSGKNNENVEEVFKQILNEVNKGSTGPEPPQKEGCILM
What is the function of this protein?
Binds GTP and exhibits intrinsic GTPase activity.
What are the official names of this protein?
GTP-binding protein Rheb homolog.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rheb family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: SUVR2_ARATH
Sequence: MAPNLHIKKAFMAMRAMGIEDARVKPVLKNLLALYEKNWELIAEDNYRVLADAIFDSHEDQAIQESEEKKADEVKEDEGCAAEVDRGKKKLHESIEDDEDVMAESDRPLKRLRRRGEGGSALASPSLGSPTLEGPSINDEENAPILLPYHPVPIENDHDAGELILTKVEPITNMPLSSIPDSVDRGDSSMLEIDKSNGHVEEKAGETVSTADGTTNDISPTTVARFSDHKLAATIEEPPALELASSASGEVKINLSFAPATGGSNPHLPSMEELRRAMEEKCLRSYKILDPNFSVLGFMNDICSCYLDLATNGRDSANQLPKNLPFVTTNIDALKKSAARMAYTSQASNDVVEICSNEHMRDAENGAVGDSMALVVVPECQLSADEWRLISSVGDISLGKETVEIPWVNEVNDKVPPVFHYIAQSLVYQDAAVKFSLGNIRDDQCCSSCCGDCLAPSMACRCATAFNGFAYTVDGLLQEDFLEQCISEARDPRKQMLLYCKECPLEKAKKEVILEPCKGHLKRKAIKECWSKCGCMKNCGNRVVQQGIHNKLQVFFTPNGRGWGLRTLEKLPKGAFVCELAGEILTIPELFQRISDRPTSPVILDAYWGSEDISGDDKALSLEGTHYGNISRFINHRCLDANLIEIPVHAETTDSHYYHLAFFTTREIDAMEELTWDYGVPFNQDVFPTSPFHCQCGSDFCRVRKQISKGKNVKKRA
What is the function of this protein?
Probable inactive histone-lysine methyltransferase that acts as regulator of transctiptional gene silencing independently of histone H3K9 methylation.  Contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci.  Forms a complex with SUVR1 and associates with the SNF2-related chromatin-remodeling proteins CHR19, CHR27, and CHR28, thereby mediating nucleosome positioning and transcriptional silencing.  Does not possess histone-lysine methyltransferase activity in vitro, and the conserved catalytic sites of SUVR2 are dispensable for its function in transcriptional gene silencing.
What are the official names of this protein?
Probable inactive histone-lysine N-methyltransferase SUVR2, Protein SET DOMAIN GROUP 18, Suppressor of variegation 3-9-related protein 2, Su(var)3-9-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Displays two nuclear localization patterns, one forming condensed foci and the other showing diffused signals.
Protein: SECD_SYNFM
Sequence: MSNLKWRALLVVVVLIVGVVYLVPTFVSTLPPGWSKFLPKDKIRLGLDLQGGMHLILEVEADQAVSNTATRLAEDLKDAFRKEKIAFNKIDKTGKWDIEVQLPGTEQQSQIGPLVEKEFPTLKWVSAETQPEGTVKVMLTVHEKEVERVQKAAIAQGLETIRNRIDQFGVSEPDIRPQGEDRILVQLPGIQDPQRAVELIGKTAQLEFKLVAEGVSPQDVKSGKAPAGTKIYPMKHTDRTTRQRTESQIVLNDRTLMSGEYITNAQVEIDRQHSSSYVALDFDAQGAKLFEKITEANVKKQLAIVLDGVVYSAPVIQETIGGGKATITGSFTDQEARDLAIVLRAGALPAPVKILEQRTVGPSLGADSINKGVLASIVGGIGTILFMLIYYRFGGVVADLALALNVLLVLAGMAAFGFTLTLPGIAGIALTIGMAVDANVLIYERIREELRLGKTPRAALETGYDRATLTILDANVTTIIAALVLLQFGTGPVRGFAVTLTVGLAANMFTAIFVTRVIFDYLLVQRRIKTLSI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL4_STAA8
Sequence: MANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASLRQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMPKKMRRLALRSALSFKAQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENEDVNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKKVEEVLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS231_ARATH
Sequence: MGKTRGMGAGRKLKQLRITQRWADKHYKKSNRGNEWKKPFACSSHAKGIVLEKIGIEAKQPNSAIRKCARVQLIKNGKKIAAFVPNDGCLNYIEENDEVLIAGFGRKGHAVGDIPGVRFKVVKVSGVSLLALFKEKKEKPRS
What are the official names of this protein?
40S ribosomal protein S23-1, S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ZGPAT_DROER
Sequence: MEEYEAQLLVVEQALENAADEAQRQDLLALKNNLQELLALTRDTEDGAPTDELPQQGDDLDDELQRLRSELNDLEAAGSSQTALDEERQLADLRTKYTAMVGEKCSAPHEHSWGTCYHNALICGVDDEVVMSSEGVLDARLRVLFTNPTHREMLPCSYYLEGECRFDETKCRFSHGALVTGSSIRKYNPPDFHKLCRSRPVFALLPDRLWHRGRVLCVNFVEQVCRVRLDGQDHKERERDFKFEELYPLTTDQEEDDELSSEESNSSMNNESSDEAESDMDDLEEARRARMVELSLFTFKPTERLGAWEEFTRGIGSKLMEKMGYIHGTGLGSDGRGIVTPVSAQILPQGRSLDACMELREAANGDKDYFSVERKLKRAQRRQRKADEKAYVRESQRVDVFTFLNDSVLAPGESSQQGEQVAKKVKTNELQQHSTKTLNVETVRIADEIRRKQRDMAKVKQSLDRNSGDAQLQKRLQVQMQSHKQELATLQAQERSLSKEQQTRKSKNKMFEF
What is the function of this protein?
Transcription repressor.
What are the official names of this protein?
Zinc finger CCCH-type with G patch domain-containing protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_CHLCH
Sequence: MLDIAYIRQNPDEVAAMLRHRQLASEEPKLQQLLECDRQRKELVQRSDEQKALRNKVSKEVAEIKKKGVGSPDELISQMKAVSDAITAMDSRLSELEAEMENLLLALPNKLHPSVPIGRSAEDNMVFGEPVHFEHSLNFPLKNHLELGKALRILDFERGAKVSGAGFPVYVGKGARLERALINFMLDMHTEQHGYTEVFPPFLVNQESLRGTGQWPKFADQVYYIGEDDLYAIPTAEVPLTNLHRGEMVETNALPISYTAYTACFRREAGSYGKDTRGFLRVHQFNKVEMVKFTRPEDSYTALEEIRHHAQAILEALKIPYRVLLLCSGDISANATKCYDIEVWSPAEEKYLEASSCSNFEEYQARRSNIRFKPDSKSKPEFVHTLNGSGLATSRLMVSLLEHYQTADGHIRVPNVLQRYTGFTEI
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YD545_YEAST
Sequence: MPAKLQLDVLRTLQSSARHGTQTLKNSNFLERFHKDRIVFCLPFFPALFLVPVQKVLQHLCLRFTQVAPYFIIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKIFQISYRVPMIWLDVFQVFFVFLVISQHSLHS
What are the official names of this protein?
Putative UPF0479 protein YDR545C-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0479 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: H2A1B_MOUSE
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-B.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NUOI_RICCK
Sequence: MINYLKSFFLYEIVRGMALTLRYFFKAKVTINYPYEKSPVSPRFKGEHALRRYENGVERCIACKLCEAICPAQAIVIEAEALDDGSRRTTRYDIDMTKCIYCGLCQEACPVDAIVEGPNFEFASLTHTALIYDKERLLQNGDKWEQALTSKLYKDYEYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ABCB3_DICDI
Sequence: MDDGNENNENAQHDEYDEEEIEIPIDEIIIEEVDDDHLLEGEGEFQIITQPSNNNNNSNNNNFGDIYVSNPNTPRNNNNNNNNNNNNNNNNNNNNNNNSNNSFNNNKKNEVSIGISENTNENNNKNNNNNNNNNDDYNDGADERVKTEEEIKKEAENELNQSVPFLSLFRFADNTDKVLMFLGTIAAVINGAAMPTVSLVFGLVVDAFKPTQFNDDPNYDIYDTVRSISFYLLMLGGGVFVLSYLETTLWMIAGERQTSRIRREYLESTLRQEIGWFDTNKANELSSRINSDTVLFEEAIGEKVGRFIHFFSTFVAGFVIGFTKGWQLTLVITSVSPLLAIGGFFTAKMMTQMTKLGQEAYSRAGGVAEENIGSIRTVATFSGEKLAIDKYSNNLKDARTVGYKRSFFNGLGLGFVQFVILGTYALAFWYGSTLISNKVTNSVSDRPWTGGDVVSVFFAVIIGATSIGQASPCLALFAQGRGAAYKIFQVIDRQSKANPFSTRGIKPETLSGEIEFKDVGFHYPSRPDVPIFNGFNLKIKPGQTVGLVGDSGGGKSTIISLLERFYDPCQGEILLDGEDIRKFNVRGLRQKIGLVNQEPVLFATTISENIRYGKEGATQDEIEEAAKLANAHSFISQLPQGYNTLVGEKGVQMSGGQRQRIAIARAVIKNPNILLLDESTSALDAESTKLVQEALDVLMKGRTTIVIAHNLSTIRNADVIIYIKKGVAVERGTHDELMAKQGLYFDLVEKQSHQQMYNLLENGTRSRRSSTFSAEVNPLLDSFHVSKRSLRKNESESNKKDKEDSNNKKKKKSNKKKVEEVPMSRVVKYNRPELGLWCFGFLSAVGTGAVYPGFAMVFTEMLTIFQNPDPNYLTDHANFVALMFVALAVGAGISNFFQGFLFSVIGEKLTYRLRRDCFAAIMRQDVGWFDLPENSTGKLTSHLATDAALVQGMTSQRLGIVLQNILTMVGGLVIAFYSGWQLTLVIIACFPLVVITSKVQMQILAGFSSKDGCGPAGQVASEAISGIRTVASFTTEKQVVELYKKQQKGPSSEGIKKAHISGFAFGFTQLILFCVYCLSFWYGGKLVGSGVFGATDKEISDNCTPQTIPYLWKDYDTCERAQNTIYGFNSMTRVFFAIVMSAIGVGQASSFAPDLAKAKAAAVSVFKLLDTPSKIDPTTEDGDRIDIVGGDIEFKNLHFSYPTRPDNSVFRGFTLTLQSGTTTALVGDSGGGKSTCLSLLQRFYNPVVGEIFIDGHNIKNLNVRHLRHLFGLVGQEPTLFSGTIADNIRYGKHDATQEEIEEASKLSNSHSFIIDLPNGYNTELGEKYTQLSGGQKQRIAIARAIIRNPKILLLDESTSALDADSTKLVQEALENVMKGRTTIVIAHNLLTIQNADCIAYVRAGQIIERGTHDELLEAEGPYSQLWYNQQQK
What are the official names of this protein?
ABC transporter B family member 3, ABC transporter ABCB.3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IPGB_SHIDY
Sequence: MQILNKILPQVEFAIPRPSFNSLSRNKLVKKILSVFNLKQRFPQKNFGCTVNINKIRDNVIDKIKDSNSGNQLFCWMSQERTTYVSSMINRSIDEMAIHNGVVLTSDNKKNIFAAIEKKFPDIKLDEKSAQTSISHTALNEIASSGLRAKILKRYSSDMDLFNTQMKDLTNLVSSSVYDKIFNESTKVLQIEISAEVLKAVYRQSNTN
What are the official names of this protein?
Protein IpgB.
Protein: UVRA_MYCTO
Sequence: MADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVLAMPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHDIEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVDHELGAPHREQRFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVDTPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESKGEHGAKSIAEVCELSIADCADFLNALTLGPREQAIAGQVLKEIRSRLGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGRIVHSGPYDELLRNKDSITGAYLSGRESIEIPAIRRSVDPRRQLTVVGAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRVTGLDYLDKLVRVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVSEVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVIKTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFLAEVVGGGASAATSRSNRRRNVSA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOD1_RAT
Sequence: MGLSQLWLWLKRLVIFLQVALEVATGKVLMTLFPERVKQNILAMGQKTGMTRNPRFAPDNWVPTFFSIQYFWFVLKVRWQRLEDRAEYGGLAPNCTVVRLSGQKCNVWDFIQGSRPLVLNFGSCTUPSFLLKFDQFKRLVDDFASTADFLIIYIEEAHATDGWAFKNNVDIRQHRSLQDRLRAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYVIQEGRICYKGKPGPWNYNPEEVRAVLEKLCIPPGHMPQF
What is the function of this protein?
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).
What are the official names of this protein?
Type I iodothyronine deiodinase, 5DI, DIOI, Type 1 DI, Type-I 5'-deiodinase.
What is the protein family that this protein belongs to?
Belongs to the iodothyronine deiodinase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: GPMA_RHOJR
Sequence: MNGMSTGTLVLLRHGESEWNALNLFTGWVDVHLTDKGIAEGKRAGELLLEHNLLPDVLYTSLLRRAISTANIALDTADRHWIPVIRDWRLNERHYGALQGRNKAQVKEKYGDEQFMLWRRSYDTPPPPIEAGSEYSQDTDPRYANLDKVPLTECLKDVVVRLIPYWEDTISADLKAGKTVLITAHGNSLRALVKHLDGISDEDIAGLNIPTGIPLRYDLDENLKPLNPGGTYLDPEAAAAGAAAVANQGGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: QUEC_VIBC3
Sequence: MKKAVVVFSGGQDSTTCLVQALKEFDEVHAITFDYGQRHKLEIEVAQQLAKQLGVTAHKVMDVSLLNELAISSLTRDDIPVSHELQANGLPNSFVPGRNILFLTLAGIYAYQIGATTVITGVCETDFSGYPDCRDEFVQAMNQALAKGMDLPLMIRTPLMWLNKAETWALADQLGALDLVRHQTLTCYNGLIGDGCGECPACGLRQAGLKAYLDNRDLIMSALKSKQSAAH
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MUKB_CROS8
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSVLDVVNSRHQRVLVGVRLQQVAGRDRKVDIKPFAIQGLPSAILPTQLLTETLNDRQARVLSLNELKDKIDTMEGVQLKQFNSITDYHSLMFDLGVVARRLRSASDRSKYYRLIEASLYGGISSAITRSLRDYLLPENGGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRIHLDQALELRRELFSSRKQLAAEQYKHVHMARELSEHAGAEGDLETDYQAASDHLNLVQTALRQQEKIERYEADLEELQIRLEEQSEVVAEAAEQQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYQQALTALERARELCHLPDLSADSADEWLDTYQAKEQEATERLLSLEQKMSVAQTAHSQFEQAYQLVASINGPVSRAEAWDVARELLRDASQQRHLAEQVQPLRMRLSELEQRLREQQDAERLLAEFCKRQGKNYDPEDLEALNDELEARIAALSDSVSQAGEQRMTLRQELEQIQSRVKTLTSHAPAWLAAQNSLNQISEQSGETFESGQQVTEYLQQLLEREREAIVERDEVGARKRAVDEEIERLSQPGGAEDARLNALAERFGGVLLSEIYDDVSFDDAPYFSALYGPSRHAIVVPDLSRVRDLLDGLEDCPEDLYLIEGDPQSFDDSVFSVEELEKAVVVKVAERQWRYSRFPSVPLFGRAARESRIESLHAEREALSERYATLSFDVQKTQRLHQAFSRFVGQHLAVAFEADPEAEIRKLNTRRSEIERAISQHENDNQQQRVQFEQAKEGVAQLNRLLPRLSLLADDSLADRVEEIQERLAEAQDAARFLSQHGKALAKLEPVASVLQSDPEQFDQLKQDYEQARQTQRDARQQAFALSEVVQRRAHFSYSDSAQMLNGNTDLNEKLRQRLEQAEAERTRAREALRTHAAKLSQYHQVLASLKSSFDTKKELLGDLQRELQDIGVRADAGAEERARQRRDELHTRLSNNRSRRNQLEKQLTLCEAEMDNLTRSLKRLERNYHEMREQVVSAKAGWCAVMRMVKDNGVERRLHRRELAYHSGDDLRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELGRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQSVSFGQVNSVRLNVNVRESHATLLEVLAEQHEQHQDLFNSNRLTFSEALAKLWQRLNPQIDMGQRTAQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDESSRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNHEHVHVVGLRGFAAPPADALPGPAEVS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: INH15_ECOLI
Sequence: MSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRARVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH
What is the function of this protein?
Involved in the transposition of the insertion sequence IS5.
What are the official names of this protein?
Transposase InsH for insertion sequence element IS5-15.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: RS17_BURP6
Sequence: MNDSVKTSLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYGKYVVRSKKYHAHDEANTYNEGDLVEIQETRPVSKTKAWAVSRLVEAARVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: YCAR_ECO5E
Sequence: MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPVLLETEARVLTADESKS
What are the official names of this protein?
UPF0434 protein YcaR.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: T2MG2_AGEAP
Sequence: ECATKNKRCADWAGPWCCDGLYCSCRSYPGCMCRPSS
What is the function of this protein?
Insecticidal neurotoxin that induces an irreversible spastic paralysis when injected into insects.  Modifies presynaptic voltage-gated sodium channels (Nav), causing them to open at the normal resting potential of the nerve.  This leads to spontaneous release of neurotransmitter and repetitive action potentials in motor neurons.
What are the official names of this protein?
Mu-agatoxin-Aa1b, Mu-AGTX-Aa1b, Mu-agatoxin II, Mu-Aga II, Mu-agatoxin-2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 07 (Beta/delta-agtx) family. 01 (aga-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LIMD2_MOUSE
Sequence: MFQAAGAAQATPSHEAKGSSGSSTVQRSKSFSLRAQVKETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLSLGSYAAMHGEFYCRPHFQQLFKSKGNYDEGFGRKQHKELWAHKEVDSGTKTA
What is the function of this protein?
Acts as an activator of the protein-kinase ILK, thereby regulating cell motility.
What are the official names of this protein?
LIM domain-containing protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly found in cytoplasm, concentrated in membrane ruffles and in streaks reminiscent of focal adhesion plaques. Also found in nucleus.