PharMolix/UniProtQA huggingface dataset:
Protein: NAA30_XENLA
Sequence: MADAPSGPSVLSHYPGAGLAGEQQREEERHKGCHHHQLNGLISPDLRHLKAVSSLKNKLLEQKTRKDSGLVQPQGRTDTRAPNGLERLQGEEEKLSACLASCSLRGDGEALGNHVSQGENDDTIRYVRYESELQMADIMRLITRDLSEPYSIYTYRYFIHNWPQLCFLAMVGEECVGAIVCKLDMHKKMFRRGYIAMLAVDSKYRRKGIGTHLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGVDALRLKLWLR
What is the function of this protein?
Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex.  Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly.  Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate.
What are the official names of this protein?
N-alpha-acetyltransferase 30, N-acetyltransferase 12, N-acetyltransferase MAK3 homolog, NatC catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MAK3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VHR2_LSDVN
Sequence: MGIRHELDILLVSENLALKNVELLKGDSYGCTINIKVNQQKKLDFIIILRPDWTEVRNVKKINMVCNGVVIDTTLIKKSFYEEVYSSSVTVFQNTTVEFFSDTSKKYKEEYPIVNINTIKRYYEIKDSRMTCINFESPISDYDQVNYLKDYINISDDYYLYDACDDCIISSDDDDDNDNADDDEEDDDEVNDIEDDYE
What is the function of this protein?
Plays a role for multiplication of the virus in different cell types.
What are the official names of this protein?
Probable host range protein 2.
What is the protein family that this protein belongs to?
Belongs to the poxviridae C7 protein family.
Protein: OPSD_LITPI
Sequence: MNGTEGPNFYIPMSNKTGVVRSPFDYPQYYLAEPWKYSVLAAYMFLLILLGLPINFMTLYVTIQHKKLRTPLNYILLNLGVCNHFMVLCGFTITMYTSLHGYFVFGQTGCYFEGFFATLGGEIALWSLVVLAIERYIVVCKPMSNFRFGENHAMMGVAFTWIMALACAVPPLFGWSRYIPEGMQCSCGVDYYTLKPEVNNESFVIYMFVVHFLIPLIIISFCYGRLVCTVKEAAAQQQESATTQKAEKEVTRMVIIMVIFFLICWVPYAYVAFYIFTHQGSEFGPIFMTVPAFFAKSSAIYNPVIYIMLNKQFRNCMITTLCCGKNPFGDDDASSAATSKTEATSVSTSQVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Required for photoreceptor cell viability after birth (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: YCFP_ECO81
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: PACS1_RAT
Sequence: MAERGGAGGGPGGAGGGSSQRGSGVAQSPQQQPPQQPSQPQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIILPASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKVKSTWIKNQDDSLTETDTLEITDQDMFGDASTSLVVPEKVKTPMKSSKADLQGSASPSKVEGTHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVVYDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGSQSYLSSILRFFVKSLASKTPDWLGHMRFLIVPLGSHPVAKYLGSVDSRYSSTFLDSAWRDLFSRSEPPVSEPLDVVGRVMQYVNGATTTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHAGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIEGISRLICSAKQQQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKPT
What is the function of this protein?
Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs.  Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin-coated membrane pits.  Required for normal ER Ca2+ handling in lymphocytes.  Together with WDR37, it plays an essential role in lymphocyte development, quiescence and survival.  Required for stabilizing peripheral lymphocyte populations (By similarity).
What are the official names of this protein?
Phosphofurin acidic cluster sorting protein 1, PACS-1.
What is the protein family that this protein belongs to?
Belongs to the PACS family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Note=Localizes in the perinuclear region, probably the TGN.
Protein: CSA3_SACS2
Sequence: MKSYFVTMGFNETFLLRLLNETSAQKEDSLVIVVPSPIVSGTRAAIESLRAQISRLNYPPPRIYEIEITDFNLALSKILDIILTLPEPIISDLTMGMRMINTLILLGIIVSRKRFTVYVRDEGGGSRVISFNDNTIRALMRDYSREEMKLLNVLYETKGTGITELAKMLDKSEKTLINKIAELKKFGILTQKGKDRKVELNELGLNVIKLNKSVIESSKSSEELVKENKGKEVNIPY
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
What are the official names of this protein?
CRISPR locus-related putative DNA-binding protein Csa3.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Csa3 family.
Protein: SYE_ALBFT
Sequence: MTQKTRTRFAPSPTGFIHLGNIRSALYPWAFARSTGGDFILRIEDTDLDRSTQAAVDVIIESMSWLGLDYDEGPFYQMQRMDRYKTVLAELQAAGHVYPCYMSVAELDALRDAQMAAKEKPRYDGTWRPAPGKTLPPIPEGVKPVLRFKNPLGGSVVWDDKVKGRIEISNDELDDLVIARPDGTPTYNFCVVVDDLDMAITHVIRGDDHVNNTPRQINIFKALGQEPPVYAHLPTVLNEQGEKMSKRNGAKPVTQYRDEGYLPDAMVNYLARLGWSHGDDEIFSRAQFLQWFNLDHLGRSAAQFDEAKLRWVNAQHLKIMSDDALAPLVQAQLQKRGIQADERLPRICALFKDRCDTTVVLADWAAAFYADITLNPAEVSQHVTDAIKPALNLLSEKLASCSWDKLSIAAAIKEVLVACAIKMPLLAMPVRVLVMGSAHTPSLDAVLELCEREKVLTRLRSE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_ANAMM
Sequence: MENQQHQVLEQELWQGYKDRGFVVTKFSDLVDSVVRWSRSGSLWPMTFGLACCAVEMMHTAASRYDLDRYGVMFRASPRQADVMIVAGTLTNKMAPALRRVYDQMAEPKYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILCLQQKIIRGNPGVRGA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EFTS_SULDN
Sequence: MEVTAAMVKDLRASTDAPMMDCKKALVECNGDMEKATAWLKERGIAQSAKKADRVAAEGLVGFKIADDFSQATVVEINSETDFVAQNDGFKNLVLKTTEEIYSTSPADVESLKSTAFGSFFSEAVVKIGEKIELRRFKTIKADDETVAINGYIHSNNRIAVIVSAKCDSKKTAEALRPMLKNVAMHASAMKPKTLSYRDFDAEYVQNETIGRIETIKKENEELARLKKPLKNVPEFISMCQLTDVVLAKAEAAIKETLKAQGKPEAIWDKIVPGQLARYIDDNTTLDKELALLDQTYVLNDKLTVGAAVEAAAKEVGGTAEIVDFVRLEVGEGIEKKVDDFAAEVAAQMS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALEU_HORVU
Sequence: MAHARVLLLALAVLATAAVAVASSSSFADSNPIRPVTDRAASTLESAVLGALGRTRHALRFARFAVRYGKSYESAAEVRRRFRIFSESLEEVRSTNRKGLPYRLGINRFSDMSWEEFQATRLGAAQTCSATLAGNHLMRDAAALPETKDWREDGIVSPVKNQAHCGSCWTFSTTGALEAAYTQATGKNISLSEQQLVDCAGGFNNFGCNGGLPSQAFEYIKYNGGIDTEESYPYKGVNGVCHYKAENAAVQVLDSVNITLNAEDELKNAVGLVRPVSVAFQVIDGFRQYKSGVYTSDHCGTTPDDVNHAVLAVGYGVENGVPYWLIKNSWGADWGDNGYFKMEMGKNMCAIATCASYPVVAA
What is the function of this protein?
May play a role in proteolysis leading to mobilization of nitrogen during senescence and starvation.
What are the official names of this protein?
Thiol protease aleurain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Vacuole. Note=Vacuole-like subcellular compartment.
Protein: ACYP_DEIGD
Sequence: MRLTALVSGTVQGVGYRRYVQRHARDLGLSGSAENLPDGRVEVVAEGPPEHLERLLHWLRRGPPHARVADVQTQYSEATGLRDFHVY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: UVSX_BPT2
Sequence: MSIADLKSRLIKASTSKMTAEL
What is the function of this protein?
Important in genetic recombination, DNA repair, and replication.  Possesses pairing and strand-transfer activity.  Interacts with dda and gene 32 proteins.
What are the official names of this protein?
Recombination and repair protein.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
Protein: ARLY_ECO27
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEDLPLSELQKFSLVIGEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIAFAQARLG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOA_THEP3
Sequence: MTEFIFLLVVIGLIFVFLSVILSFIPLGLWISALAAGVKIGIFTLVGMRLRRVPPDKIVKPLIKAIKAGQDVEINKLEAHYLAGGNVDKVIDALIAAQRANISLEFERAAAIDLAGRDVLHAVQMSVNPKVIETPVVAAVAKDGIEVKVKARVTVRANIDRLVGGAGEETIIARVGEGIVTTVGSSNSHKEVLENPDSISRTVLNKGLDAGTAFEILSIDIADVDVGRNIGARLQIDQAEADKRIAQAKAEERRAMAVAREQEMKAMVQEMRAKVVEAEAEVPKAMAEALRTGKIGVMDYYNMRNVIADTMMRESFSKLGQERQQEEKE
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: CDC72_ENCCU
Sequence: MEEEKILESDLRHISFVMPKYTPIEKIGEGSFSVVYKALDAESGRYVALKAITRTSSPARVLDEMMFLKTLGGRKNCMGLLGCFRNEDQVVAVFPYFEPIDFREFISNANLADIKRYLHNLLIAIEHVHSNGIMHRDLKPGNFLYNKESGRGMLIDFGLAQYEEYSEGQHAEGGAKPAGPLLFFNSVVSKTKPPGYYERDGRPPMKAPRAGTRGFRAPEVLFRCQRQTGAIDMWSVGVIFLTILTTQYPFFYSSDDIDSIVEIATIFGHAEMRKAAKFYGRVWRSNIDSIPEERIPFETIVESLNPWAEVGSDGYDLLYRMLDLCSSSRITASDALSHPFFDDLKTHENCA
What is the function of this protein?
Serine/threonine-protein kinase.  Needed for the initiation of DNA synthesis during mitosis as well as for synaptonemal complex formation and commitment to recombination during meiosis (By similarity).
What are the official names of this protein?
Probable cell division control protein 7 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily.
Protein: LEUD_FRATO
Sequence: MQAFKKLTSSAIPLWLSDIDTDMIIPANFLTQTTKDGYGKSLFHNLKEKDSSFVFNNPDYSNSEILIAGDNFGCGSSREHAVWALTQAGIKVIIAPSFSDIFFNNAAKNGLLLISLDKDTVKELCDKAEDPKFSMTIDLQEQTVSADGSIYSFDYDPFRKDCLIRGLDDMTYLIEHLDIIKQFEQSQRG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RL6_SALDC
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNALTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLSLGFSHPVDHQLPAGITAECPTQAEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MIAA_LYSSC
Sequence: MIENKLQQAEVVAIVGPTASGKTALSIELAKKYNGEIINGDSMQVYKGLDIGTAKITEEEMEGVPHHLLSFLEPTASFSVADYQKLVREKIADIQARHKLPIIVGGSGLYVQAVLFDFQFTDEKVDEAARQAYYDELAKLGPEAMHDKLKQLDPQTAEAIHPNNTRRVIRALEMLELSGVSKAAEAQNRGEVPLYNHLILGLGQNMSREVLYDRINRRVDLMMENGLLEEVQGLWQQNIRGVQSIQAIGYKELYDYLDGKCSLEGAIDSLKQNSRRYAKRQLTYFRNKMDVHFVMTGEQL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: HPF1_YEAST
Sequence: MFNRFNKLQAALALVLYSQSALGQYYTNSSSIASNSSTAVSSTSSGSVSISSSIELTSSTSDVSSSLTELTSSSTEVSSSIAPSTSSSEVSSSITSSGSSVSGSSSITSSGSSVSSSSSATESGSSASGSSSATESGSSVSGSSTSITSGSSSATESGSSVSGSTSATESGSSASGSSSATESGSSASGSSSATESGSSVSGSSSATESGSSVSGSSSATESGSASSVPSSSGSVTESGSSSSASESSITQSGTASGSSASSTSGSVTQSGSSVSGSSASSAPGISSSIPQSTSSASTASGSITSGTLSSITSSASSATATASNSLSSSDGTIYLPSTTISGDITLTGSVIATEAVEVAAGGKLTLLDGDKYVFSADFIIHGGVFVEKSKPTYPGTEFDISGENFDVSGTFNAEEPAASSASAYSFTPGSFDNSGDISLSLSESTKGEVTFSPYSNSGAFSFSNAILNGGSVSGLQRRAESGSVNNGEINLENGSTYVVVEPVSGSGTINIISGNLYLHYPDTFTGQTVVFKGEGVLAVDPTETNTTPIPVVGYTGENQIAITADVTALSYDSATGVLTATQGNSQFSFSIGTGFSSSGFNVSEGTFAGAYAYYLNYGGVVASSATPSSTSTTSGATNSTSGSTSFGASVTGSTASTSFGASVTGSTASTLISGSPSVYTTTLTYATTTSTVVVSCSETTDSNGNVYTITTTVPCSSTTATITSCDETGCHVTTSTGTVATETVSSKSYTTVTVTHCDNNGCNTKTVTSECPEETSATTTSPKSYTTVTVTHCDDNGCNTKTVTSEAPEATTTTVSPKTYTTATVTQCDDNGCSTKTVTSEAPKETSETSETSAAPKTYTTATVTQCDDNGCNVKIITSQIPEATSTVTATSASPKSYTTVTSEGSKATSLTTAISKASSAISTYSKSAAPIKTSTGIIVQSEGIAAGLNANTLNALVGIFVLAFFN
What is the function of this protein?
Involved in cell wall organization and biosynthesis.
What are the official names of this protein?
Haze protective factor 1.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI- anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI- CWP), enriched at bud sites and their neighborhood.
Protein: DES1_SORBI
Sequence: MATTPMTVVDHEAEEAVAKAREDDKSRQVDAFDAGKPPPFRIGDVRAAVPEHCWHKSPWRSLWYVVRDVAAVVALGTAAAAMDSWAVWPVYWAVQGTMFWAFFVLGHDCGHGSFSDSRTLNSVVGHLLHSFILIPYHGWRISHRTHHQNHGHVDRDESWHPITEGRYRRLPPRAKKIRFTAPYPLLLFPLYLFYRGPDKPGTHFLPSSELFSPKEKGDVMLSTTCWCIMLASLLAMSCAFGPLQVLKMYGLPYLVFVMWLDLVTYLHHHGHHERLPWYRGEEWSYLRGGLTTVDRDYGWINKIHHDIGTHVIHHLFPQIPHYHLVEATKAAKPVLGRYYREPQKSGPLPLPLLGVFLRSIRVNHFVSDHGDVVYYQTDHHLNDTTKQK
What are the official names of this protein?
Probable fatty acid desaturase DES1, SbDES1.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NC2B_ARATH
Sequence: MDPMDIVGKSKEDASLPKATMTKIIKEMLPPDVRVARDAQDLLIECCVEFINLVSSESNDVCNKEDKRTIAPEHVLKALQVLGFGEYIEEVYAAYEQHKYETMQDTQRSVKWNPGAQMTEEEAAAEQQRMFAEARARMNGGVSVPQPEHPETDQRSPQS
What are the official names of this protein?
Protein Dr1 homolog, Negative cofactor 2-beta homolog, NC2-beta homolog.
What is the protein family that this protein belongs to?
Belongs to the NC2 beta/DR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UNG_VARV
Sequence: MNSVTVSHAPYTITYHDDWEPVMNQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLHHITKHVSVLYCLGKTDFSNIRAKLESPVTTIVGYHPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
What is the function of this protein?
Plays an essential role in viral replication as a component of the DNA polymerase processivity factor.  Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Protein: RL16_AMOA5
Sequence: MLQPKRTKYRKVQKGRVKGLAHRGSSLAFGTFGIKALEAIWLTARQIEAARIAMTRAMKRQGQVWIRVFPDKPITKKPAEVRMGKGKGSPEYWAAVVKPGKILFEIEGVDINLAREATRLAIHKLPIKAKFVVHKDYINA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CHM4C_DANRE
Sequence: MSVFGKLFGGGGKGGKGPTPQEAIQKLRETEEMLAKKQDFLEKKIDAELLIAKKNGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKTAHENMDIDKVDDLMQDITEQQELAQEISDAISRPVGFGEEFDEDELMAELEELEQEELDKDLLQISGPEDVPLPNVPSNPLPKKTAVAQKKRQEEDEDDMEELKAWAM
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 4c, Chromatin-modifying protein 4c, CHMP4c.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein.
Protein: SECA2_STRSV
Sequence: MIKNHFQIQRLKKILAKVKSFESEMAGLTDAELRKKTQEFKERLAAGETLDDLLPEAYAVVREADKRVLGMFPYDVQVMGAIVLHEGNVAEMATGEGKTLTATMPLYLNALSGQGAMLVTTNTYLALRDAQEMGQVYRFLGLTIEAAVVADETENLTPKQKRLIYQADIVYTTNSALGFDYLIENLAENKDSQYLSPFNYVIIDEIDSILLDSAQVPLVISGAPRVQSNFYSIMDTFITTLKEEEDYHYDDEKNEVWLTSKGILAAESFLDLEHLFSKENQELVRHLNLALRAHKLYKKDKDYVVRQGDKEAEVVLLDRATGRLLEMTRLQGGQHQAIEAKEHVKLTEETRAMASITYQNLFRLFRKISGMTGTGKVVESEFMETYSMSVIKIPTNQPVIRQDLPDQLYQTLPEKVFASLDEVKHYHAQGNPLLIFTGSVEMSEIYSSLLLREGIAHNLLNANNAAREAQIIAESGQKGAVTVATSMAGRGTDIKLGPGVADLGGLVVIGTERMENQRIDLQIRGRSGRQGDPGISKFFISLEDDLLRKWGPDWLKKLYKDYSTEEVQQHPVQLGQRRFRRLVAKAQRASESSAKMSRRMTLEYAQCMKIQREITYAERNRLIQAEERIDEEISRVLSQVIHQAAYEQSYETRADLYRFILDHFSYHAERIPYDFDIYSPEKIAELLQDIAEQELQAKKAYLKSDKLFTHFQRVSVLKAIDENWVEQVDYLQQLKTALSGQHFSMKNPLVEYYQEAYDGFEYMKERMKQQIVKNLLMSELALNPKGEVIMYFP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: THII_MANSM
Sequence: MKFVIKLFPEIMIKSESVRKRFVKILTGNIRNVLNKYDDGVAVVKHWDYIEVRSKNEENRAILIDVLGRIPGIHHFLEVDEKPFTDMHDIFEQTLADVGASLENKTFCVRVKRKGKHEFSSLDVERYVGGGLNQAIETAKVKLSNPDVTVRIDIENDHMMLIKARHEGIGGYPIGTQEDVLSLISGGFDSGVSSYMFIRRGSRVHYCFFNLGGAAHEIGVKQMAYHIWNRYSGSHKVRFVAINFENVVGEILEKIDNGQMGVVLKRMMVRAASKVAERFGIQAIVTGEALGQVSSQTLTNLRLIDEAASALVLRPLITHDKEAIIAMAKQIGTDDIAKSMPEFCGVISKNPTVKAIKEKIEKEELNFNFDVLESAVQNAQYLDIRQIAEQTEKDVVKVDTVSVLSANDVILDIRSPEEHDERPFELAGHEVKHLPFYKLSSQFGDLDQSKNYVLYCERGVMSKLQALYLKENGFANVRVFAHGNIN
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASL_ENTFU
Sequence: MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQLAPTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQHKQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQELPFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFIPGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKAFLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFNKPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKDRSIKRWLLMKYMFHNYIPRFKKYFHVKEG
What is the function of this protein?
Catalyzes the addition of D-aspartate onto the lysine residue in the peptidoglycan precursor UDP-MurNAc-pentapeptide.  The ligation occurs between the beta-carboxylate of D-Asp and the epsilon-amino group of L-Lys.  Is highly specific for D-aspartate, as L-aspartate, D-glutamate, D-alanine, D-iso-asparagine and D-malate are not substrates.
What are the official names of this protein?
D-aspartate ligase, Asl(fm), UDP-MurNAc-pentapeptide:D-aspartate ligase.
Protein: YQZM_BACSU
Sequence: MNDFEKNVQSKRNDAVDSAVGFVVSFGFFAFLFVMATVIHLVGS
What are the official names of this protein?
Uncharacterized membrane protein YqzM.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.