PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_BIFA0
Sequence: MLDVNAFDKLKIGLATADDIRGWSYGEVKKPETINYRTLKPEKDGLFGEQIFGPTRDWECACGKYKRVRFKGIVCERCGVEVTRSRVRRERMGHIELAAPVTHIWFFKGVPSRLGYLLGIAPKELEKVIYFASYMVTSVDEEQRHQDLPDLQDEFDHEVQNLERRRNNEIEERAKKLEADLAELEADGEVKGSAKTKLRNGAERDMAAIRQRYDDQIKRIAAVFDKFKSLKPGDMESDVDLWREMEDRYGDYFEGCMGAEAIKKRLQDFDLEAAAKELREEIETGTGQRKARALKRLKVVNAFLTTDNKPEAMVLDVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIELGAPEIMLNNEKRMLQEAVDSLFDNGRRGRPVTGASNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPSLRMHQCGLPKPMALELFKPFVIKRLVDLNYAQNMKSAKRLVDRGDSEVWGVLEEVISEHPVLLNRAPTLHRLGIQAFEPILVEGKAIHLPPLACAAFNADFDGDQMAVHLPLSAEAQAEARSLMMASDNILKPADGHTVTMPSQDMILGLYYLSTVIDGAKGQGRIFSSLEEAQMALDKHEIDMQAKVLIRLPQDFVLPKDWEPGEVQVIDPEPGSPDVVKEERFADGSVLFATSLGRILFNDTLPVDYPFINEQAPKGKLSKIVDDIATRYSTQQVAATLDALKDLGFTRAPWSGVTMAFSDIVAPPDREEIIKGYEAQAAKVNNQYDLGLLTEEERRQELINLWTECTDKVAEAMRENFHDDNNVNIMVQSGARGNWMQIRQIAGMRGLVANPKGEIIPRPVKSNYREGLSVLEYFISQHGARKGLADTALRTAESGYLTRRLVDVSQEIIVREEDCGTTHGLPMTVAERDENGNLVLVKAADGGPYSRLLAQDVLDPADGKTVLYHAGDALSMDVLNDLVAHGVEQVIGRSVLTCESKRGVCAKCYGWSLATNKLVDVGEAVGIVAAQSIGEPGTQLTLRSFHSGGVASASDITQGLPRVTELFEARTPKGEAPISEFAGTIKVQDTERGREVILQPDDDSLEPITYQVTRRAPMLVKDGQHVDPGTQLVEGSVDPKKILRILGPRAAQMNIVNEVHDVYRSQGVDIHDKHIEVIVHQMLRRVTVIDSGDTDLLPGELVDRARFREQNKKTVAAGGRPAAGRPELMGITKASLATDSWLSAASFQETTRVLTEAALNEKEDDLKGLKENVIIGKLIPAGTGLARYRNATVEPDKAIRDTIYPNFGLGDGSLGGDLSDGDLGDVDFSNIDFGDLKLGDDFNPDDFLDDNDNPVDFGDEFRIDPDELK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RAB43_HUMAN
Sequence: MAGPGPGPGDPDEQYDFLFKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQERFRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLSELREVSLAEAQSLAEHYDILCAIETSAKDSSNVEEAFLRVATELIMRHGGPLFSEKSPDHIQLNSKDIGEGWGCGC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  The low intrinsic GTPase activity of RAB43 is activated by USP6NL.  Involved in retrograde transport from the endocytic pathway to the Golgi apparatus.  Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network.  Required for the structural integrity of the Golgi complex.  Plays a role in the maturation of phagosomes that engulf pathogens, such as S. aureus and M. tuberculosis.
What are the official names of this protein?
Ras-related protein Rab-43, Ras-related protein Rab-41.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
Protein: POTEG_HUMAN
Sequence: MVAEAGSMPAASSVKKPFGLRSKMGKWCRHCFPWCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCRHCFPWCRGSSKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKSKVGPWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCREDECALMLLEHGTDPNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHNVICQLLSDYKEKQMLKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEEMSQEPEINKGGDRKVEEEMKKHGSTHMGFPENLPNGATADNGDDGLIPPRKSRTPESQQFPDTENEQYHSDEQNDTQKQLSEEQNTGILQDEILIHEEKQIEVAENEF
What are the official names of this protein?
POTE ankyrin domain family member G, ANKRD26-like family C member 2, Prostate, ovary, testis-expressed protein on chromosome 14, POTE-14.
What is the protein family that this protein belongs to?
Belongs to the POTE family.
Protein: TR125_MOUSE
Sequence: MMGIAIDILWAAIIIVQFIIGNIANGFIALVNIIDWVKRRKISLMDKIITALAISRIYLLWSTFLITLTSSLDPDIKMAVKIIRISNNTWIIANHFSIWFATCLSIFYFLKIANFSNYIFLYLRWRFKKVVSVTLLISLIFLLLNILLMNMHIDIWSDKSKRNLSFSVRSNNCTQFPRLVLLINTMFTSIPFTVSLLAFLLLIFSLWRHLKTMQYYAKGSEDTTTAAHIKALHMVVAFLLFYTVFFLSLAIQYWTSGSQENNNLFYATIVITFPSVHSCILILRNSQLRQASLLVLWWLLCKSKDVRMLVP
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 125, T2R125, mT2R59.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PDXH_ANAMM
Sequence: MIDFFEGVSWLIMPFSGVCVREADSSPMDVFGLWYSEMLRATGAHMREPSAMVLATCDVQNRPSARVVLLKKYGEAGFEFVTNFNSRKGREIADNPQVALVFDWRHIGRQVRVEGLATLMDASESDAYHASRSRESKISAWCSQQSAVLESRKLLLEQFERERQRFDGQEIPRPGHWGGVRVVPHVVEFWEDGAHRLHSRKQYSRGDSGSWSCVDLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: HEM3_PROMA
Sequence: MALDQVRIASRRSQLAMVQTNWVKEELEKACPSIDISIEAMATQGDKILDVALAKIGDKGLFTKELEAQMLIGRADIAVHSLKDLPTNLPEGLMLGCITKREDPADALVVNKKYKNYQLNDLPEGSVVGTSSLRRLAQLRHHYPGLIFKDVRGNVITRLEKLDSGEYDCLILAAAGLTRLGFGNRIHQLIPSEISLHAVGQGALGIECVKDKEEILQIIKVLEHKESSLRCLAERAFLKELEGGCQVPIGVNSKIQGQELILTGMVASLDGKQLIRDTKTGSSMHPETIGIELANTLKSQGAMEILEVIFKEARA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RSMC_ENT38
Sequence: MSAFTPASEVLLRHSDDFEQSRILFAGDMQDDLPGRFECAASRAHTQQYHHWQLLSRQMEDRVRFSLVAEQSDVADCDTLIYYWPKNKPEAQFQLMNLLSMMPVGCDIFVVGENRSGVRSAESMLAEYATLNKIDSARRCGLYHGRLDKQPTFDAEKYWGEYQLDGLTIKTLPGVFSRDGLDVGSQLLLSTFTPHTKGKVLDVGCGAGVLSAVLASHSPKVRLTLSDVSAPAVEASRATLAANGLEGDVFASNVFSEVTGRFDIIISNPPFHDGMETSLEAAQTLIRGAVRHLGSGGELRIVANAFLPYPKLLDEIFGFHEVLAQTGRFKVYRTVMTRQAKK
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSP4_DABRR
Sequence: VVGGDECNINEHPFLV
What is the function of this protein?
Snake venom serine protease homolog that may act in the hemostasis system of the prey.
What are the official names of this protein?
Vipera russelli proteinase RVV-V homolog 4, RVV-V 4, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RAPA_ALIFM
Sequence: MSFALGQRWISDTESDLGLGTVVAVDDRTVSLLFAASEENRLYAKHDAPVTRVMFNKGDTIESHEGWSLDVEDVIEEGGLLTYIGTRVDTDEANVVLRETLLSHQIRFNKPQDKLFAGQIDRMDRFALRFRALQNQYEQHKSPMRGLCGMRAGLIPHQLFIAHEVGRRYAPRVLLADEVGLGKTIEAGMIIHQQVLSGRAERVLIVVPETLQHQWLVEMMRRFNLHFSIFDEERCVEAYADSENPFDTAQFVLCSLDFIRKSKRRFEQVVEADWDLLVVDEAHHLEWNQTKPSREYQVIEAIAEETPGVLLLTATPEQLGHESHFARLRLLDPDRFYDYDAFVEEERQYQPVADAVTALMSGEKLSNDAKNRITELLSEQDVEPLFRIIESSAAEDEQAQARQELVDNLMDRHGTGRVLFRNTRAAIKGFPQRNLNLMPMPLPSQYATSMRVATMMGGRMTDEARAMKMLYPEEIFQEFEGDSATWWQFDPRVNWLLELLKENRNEKVLIIASRASTALQLEQALREREGIRGTVFHEGMSIIERDKAAAYFAQEEGGAQVLICSEIGSEGRNFQFANQLVMFDLPFNPDLLEQRIGRLDRIGQKRDIEIHVPYLQGTSQELLARWFDEGLNAFGETCPTGRAVYDKFADAIIAILATGKSDGLESLIEESAALNKSLKAQLEQGRDRLLEVHSNGGDKAKEIAEQIAATDGDTNLVNFALNLFDTIGLNQDDKGENAIVVTPAENMLVSSYPGLPYEGCTITFDRETALSREDMNLISWEHPMIQGGIDLVLTEGVGATAVSLLKNKALPAGTLLLELVYVVDAQAPKQSGIARFLPKTPIRIMMDGKGNDLSAQVEFESFNRQLSPVNRHMASKLVNSVQKEIHGLIDKAEISMEERLESVRTDAEKEMKAALNSELERLQALKAVNPNIRDEELTQIETQMSELSGYIGKAQVQLDSLRLIVVSHN
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: TIG_HELPG
Sequence: MNLEVKKIDTANARLSAKPSVEDLEKRYDKIAQKIAQKVKIDGFRRGKVPLSLVKTRYQAQIDQDAQEEMIQEVLKNAFKELGIENKDLIGSPNLTKFEKKDAHFEIEADIGLKPTIVLDKIKECVPSVGVEIPNEEKINERLKQLAKDYAKFVDTDAQRKAQNDDKLTIDFEGFIDNAPFEGGKAENFTLILGNKQMLEDFEKALLGMQASEEKEFPLTFPSGYHAEHLAGKEALFKVKLHQIQAREALEINDELAKIVLANEENATLKLLKERVKGQLFLENKARLYNEELKEKLIENLDEKILFDLPKTIIEQEMDLLFRNALYSMQAEEVKSLQESQEKAKEKRESFRNDATKSVKITFIIDALAKEEKIGVHDNEVFQTLYYEAMMTGQNPESLIEQYRKNNMLAAVKMAMIEDRVLAYLLDKNLPKEQQEILEKMRPNAQKTQAG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PROA_YERPN
Sequence: MNLLEHMGKAAKQASWQLAMLSTAKKNQALAVIANLLESESQTILQANERDMAAARESGMSEALLDRLLLTPARLAAIANDVRQVCRLNDPVGRVIDGSLLDSGLKLERRRVPLGVIGVIYEARPNVTIDVASLCLKTGNAVILRGGKETHYTNQATVNVIQRALEQCGLPAAAVQAIESPDRQLVNELLRLDRYVDMLIPRGGASLHKLCREQSTIPVITGGIGVCHTFVDENADFEKALLVIENAKIQRPSACNSLETLLVHQAVAKTFLPLLSARMHAFGVTLHASPLAMPYLADGKAKVVAVEAADYDDEWLSLDLNVDIVTDIDAAIDHIREHGTSHSDAILTRSLSHAEYFVRAVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLDALTTYKWIGYGDDLVRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERJ5_YEAST
Sequence: MNGYWKPALVVLGLVSLSYAFTTIETEIFQLQNEISTKYGPDMNFYKFLKLPKLQNSSTKEITKNLRKLSKKYHPDKNPKYRKLYERLNLATQILSNSSNRKIYDYYLQNGFPNYDFHKGGFYFSRMKPKTWFLLAFIWIVVNIGQYIISIIQYRSQRSRIENFISQCKQQDDTNGLGVKQLTFKQHEKDEGKSLVVRFSDVYVVEPDGSETLISPDTLDKPSVKNCLFWRIPASVWNMTFGKSVGSAGKEEIITDSKKYDGNQTKKGNKVKKGSAKKGQKKMELPNGKVIYSRK
What is the function of this protein?
DnaJ-like chaperone required for the folding capacity of the endoplasmic reticulum.
What are the official names of this protein?
ER-localized J domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
Protein: TRUA_METNO
Sequence: MPRYKLVVEYDGTAFAGWQRQAADRTVQQALEEAIERFVNRPVRVHCAGRTDAGVHASHQVVHLDLDREWRTDTVRDATNAHLRPEPVSVLSAARVGPDFDARHSALKRHYRYRILNRRSPPALARGYVWHVPWALDAAAMHAAAQTLLGRHDFSAFRAAECQASSPLRTLDQLDVERRGDEILVATSARSFLHHQVRGMVGTLMLAGSGRLDTAGVRAVLDSRDRARCGPLAPAAGLTLTGVDYPEAALSAPG
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: EX3L1_MOUSE
Sequence: MDSKIQPTLRPGSSCPRPEWPEQERAEQLARGAALKWASGIFYRPEQLTRLGQYRSREIQRNYSLEARIKSVVQSYLEGVQTGVWQLTRALEAVQGTREALSQAHHLLKGLSRTSQTLEPLRECVVQHKQLQILTRLLPRLQAVPATVAHTQTLIDSERLLEAYVSLRELEQLKEETLAPLGGLELPIFQGLGLLAEALGQAVEAAAGAAGRLAREDPALLVAAIRVAEVETERTILGQAPRDWRQRCLRALQEGLERVHFASPVLPEPGALAGWLEALQVALPAELATAEALVAPCCPPSYRVVELWAHTLHSGLRRSVQQLLAGPELGAADTFALLHWALHVYTGKEMMGNLELGPEADVSQLEPLLTSENIEQLEAAFVAQVQVSVAQWLKKALDGEVAEWSGEQEPPTDPSGFYHSPMPAIVLQILAENIQVTNLISDSLHRRAHNMAVSELGAFLRSFSDALIRFSRDHLRGDAVAPHYVPYLLSAFNHQSALRSSVSVLLPDGEASGVLAPVEAALDDVQRRICRLVLEVLQVELQPLFSALPSRRWLLSSELLDGVCEQTSHFCQDFWRVRKPGVQLLLAEAERTVVLQYLRALMQGRLVCRGTDERSQAAERLRQDAAQLKELFLGLGLEESAHCAPVLLALRELLNLHDPTLLGLEVAGLRQQFPDVSEDHVSALLDLRGDVSREHRQAALSSLQAGPPPSPSTGRRALFSLVPTPTPSLSSCLPSGPCS
What is the function of this protein?
As part of the exocyst, may play a role in regulated exocytosis of insulin granules.
What are the official names of this protein?
Exocyst complex component 3-like protein.
What is the protein family that this protein belongs to?
Belongs to the SEC6 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Colocalizes with insulin granules.
Protein: PLSX_BURM1
Sequence: MTVKLTIDCMGGDHGPSVTVPAAVKFVRAHPDAHLMLVGIESAIRAQLKKLKALDDPALSIVPATEVVAMDDPVEVALRKKKDSSMRVALNHVKDGEAQACISAGNTGALMAVSRYVLKTLPGIERPAIAFSLPNPTGYTMMLDLGANVDCEPQHLLQFAEMGHALVAALEGKDRPTIGLLNIGEEVIKGNETIKRAGELLRASTLNFRGNVEGNDIYKGTVDVIVCDGFVGNVALKTSEGLAQMLSDIIREEFGRSLLSKLMALLALPVLMRFKKRVDHRQYNGAALLGLKSLVIKSHGSADAYAFEWAIKRGYDAVKNGVLERLTRAMADNSVSLGDGEHDAGGAGPASPAAGHHAEPSAAQSSKA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ATG8_BOTFB
Sequence: MRSKFKDEHPFEKRKAEAERIRQKYNDRIPVICEKVEKSDIATIDKKKYLVPSDLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYISYSGENTFGEALEEAN
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  With atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Participates also in membrane fusion events that take place in the early secretory pathway.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier atg8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
Protein: FRS2_MOUSE
Sequence: MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGVMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERSSHQTELEVPRTPRTPTTPGLGAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRASVHVPPEARVSNAESNTPKEEPSNPEDRDPQVLLKPEGVRFVLGPTPVQKQLMEKEKLEQLGKDPVSGSGAGNTEWDTGYDSDERRDVPPVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRPALLNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIDYSKRRDCTPTVFNFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM
What is the function of this protein?
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways.  Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1.  Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
What are the official names of this protein?
Fibroblast growth factor receptor substrate 2, FGFR substrate 2, FGFR-signaling adaptor SNT, FRS2-alpha, Suc1-associated neurotrophic factor target 1, SNT-1.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: COP1_STAAU
Sequence: MTFNKFLKYLISLFFLSILFHVITHKNNLVFTNYDNKKSCFFPFLCMFFTSHLKRYINRYEKATFFALKTSHTNNLRVTSLAGNSYPYYQDKKEKDFSLRSNPLKKHKRPHFLMWSLFFN
What is the function of this protein?
Putative control of replication message.
What are the official names of this protein?
Protein cop.
Protein: MIAB_XANOM
Sequence: MPGTSVSDLSTATAVDAPALLPLPVARPSAPAVVRGKLYIKTHGCQMNEYDSAKMADVLAASEGLELTDNPEEADVVLVNTCSIREKAQEKVFSQLGRWKALKAGGKPVIIGVGGCVASQEGEAIVKRAPYVDLVFGPQTLHRLPELIRARRESGKSQVDISFPEIEKFDRLPEPRAEGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPFEDVLVEVAQLAAQGVREINLLGQNVNAYRGAYGADAGDAAQYADLGLLIRTIAQIEGIGRIRFTTSHPLEFSDSLVDAYRDVPQLANYLHLPVQAGSDRILSAMKRGYTALEFKSRIRKLRAVRPDISISSDFIVGFPGETEADFEKTMKLIEDVGFDQSFSFVYSRRPGTPASDLQDDTPETVKQARLARLQAHISAHAASISQSMVGSVQRVLVEGPSRRDPNELTGKSENMRPVNFPGNPRLIGQFVDVLITEAMSNSLRGRIQLDDSAH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB2_LACLA
Sequence: MATTYDWSQRKIMVPEKEEIALSTNDLRVFYNGTKEAIHGVTMSFPKNEITALIGPSGSGKSTYLRALNRMNDTIDGARVTGEINYEGVNINENKVNVFEVRKQIGMVFQRPNPFPKSIYENIAFIHRRDGVRDRKKLDEIVETSLKQAALWDQVKDNLNQSALAMSGGQAQRLCIARALSVKPEIILMDEPASALDPISTMQIEETMMELKENYTIIIVTHNMAQASRASDNTAFFYSGDLIEYDKTSTIFTQPSLQSTEDYVSGHFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: IOVO_STRCA
Sequence: FATVDCSDYPKPVCPLDYMPLCGSDSKTYSNKCNFCNAVVESSGTLTLRHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUC_LISIN
Sequence: MGKTLFDKLWNRHVIYGKEGEPQLLYVDLHLIHEVTSPQAFEGLRMENRPLRRPDKTFATMDHNVPTEDIFNIQDLVAKKQIEALQTNCEEFGVTLADMGSDRQGIVHMVGPETGLTQPGKVIVCGDSHTATHGAFGAIGFGIGSSEVEHVFATQTIWQQKPKSMGIEINGKLPKGVYAKDIILHLIATYGVAFGTGYAVEYYGETIRNMSMEERMTICNMAIEGGAKMGMMAPDQTTFEYVRGREYAPSDMEKAIRDWETLKTDPDAEYDLHIEMDASILEPYVTWGTNPEMGVPFSKAFPEIKDMNYERAYEYMGLKPGQTAEEIELGYVFIGSCTNARLSDLEEAARIVKGNKVKNNIRALVVPGSRQVRNAAEAIGLDKIFKDAGFEWREPGCSMCLGMNPDQVPDGVHCASTSNRNFEGRQGKGARTHLVSPAMAAAAAINGHFIDIRKEAVISGGN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: NPY_ONCMY
Sequence: YPVKPENPGEDAPTEELAKYYTALRHYINLITRQRY
What is the function of this protein?
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
What are the official names of this protein?
Neuropeptide Y, NPY.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL3_MYCS5
Sequence: MKGILGRKVGMTQIYSETGTAIPVTVIEVKPNVVTKVLTKQSNGYEAVQLSVFDKREKLSNKPETGHFKKANTTPKRFVKEIRNMNGYELGQSVLVNIFSVGELVDVSGTSKGKGFAGAIKRYNQHIGPKSHGGGGGSQPIRQTGSLGDISGNRVFKGMTMPGHLGSEKATLQNLEVVKVDLKENLLLVKGSVPGAKNSFVVVKSAVKGLPAKAAVKLVDVKEVVLMNELVEKAKKLNVEVKVGMHSDELRPLIEQAELEAAKEKEGE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: G6PI_PSEA8
Sequence: MKHHLTPLDATQLDSWRALAAHRQELQDFRMRQAFIDDPERFKRFSFSACGLFLDFSKNLIRQDTIDLLVKLAEEARLSDAIRAMFDGEAINASERRPVLHTALRRPIGDKVLVDGVDVMPEVHRVLHQMTELVGYVHNGLWRGYTEKPITDVVNIGIGGSFLGPQLVSEALLPFAQKGVRCHYLANIDGSEFHELASRLNAETTLFIVSSKSFGTLETLKNAQAARAWYLAQGGTEEELYRHFIAVSSNKEAAIAFGIREENIFPMWDWVGGRYSLWSAIGLPIAMSIGISNFKELLSGAYNMDQHFQTAPFERNIPVLLGLLGVWYGDFWGANSHAILPYDYYLRNITDHLQQLDMESNGKSVRQDGTPVTSGTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVPVSSYNPVADHHQWLYANCLSQSQALMLGKSREEAEAELRAKGLPEAEVQRLAPHKVIPGNRPSNTLVVERISARRLGALIAMYEHKVYVQSILWGINAFDQWGVELGKELGKGVYSRLVGSEETPAEDASTQGLIDFFRGRHRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAN_SCHMA
Sequence: MGRIQIVYSPDENVSGRTNRPGKEVVDPRTGRIIKVKRETPDDYLNVLKPIKGPKRMEFNPYLPKTLTPKGYAKFKLMMNVASKQYETLVKRLKTERTLWEDPDFPANDKAIGNLPDFRERIEWKRPHEINPNAKFFAGGASRFDIEQGALGDCWLLAVVASISGYPQLFDQVVPKDQELKGPEYVGVVRFRFWRFGHWVEVLIDDRLPVRQGRNTLVFMHSNDPTEFWSALLEKAYAKLNGCYAHLSGGSQSEAMEDLTGGICLSLELNQKERPSDLIDQLKIYAQRCCLMGCSIDSSVMEQKMDNGLIGSHAYSLTGVYPVNYRGRTQWLMRLRNPWGDSHEWKGAWCDGSPQWREISEQEKKNINLSFTADGEFWMSYEDFVTCFSRVEVCHLGLESLEYNQNFHGKRRLDEAIFSGQWQRNVNAGGCINNRTTYWTSPQFRITVEDPDPDDDDNKCSVLIGLMQTDIRKKVGADFQPIGFMVYNAPDDLNTLLSRAQLLTRSPIAKSQFINTREVTAQFRVPPGSYVVIPSTFDPNIEVNFILRVFSQTSITEQELDEDNTNQGLPDDVIEALKLEDTLLDEDQEIEQKFLAIRDPKTNAINAVKLGELLNNSTLQDIPNFQGFNKELCRSMVASVDNNLTGHVELNEFMDLWIQAKGWKHIFIKHDVDQSGYFSAYEFREALNDAGYHVSNRLINAIINRYQDPGTDKISFEDFMLCMVRLKTAFETIEAHPKNIEGTSLFSAEDYLRFSVYI
What is the function of this protein?
Calpains are calcium-activated non-lysosomal thiol-proteases.
What are the official names of this protein?
Calpain, Calcium-activated neutral proteinase, CANP.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.