PharMolix/UniProtQA huggingface dataset:
Protein: LOLD2_CHLCH
Sequence: MIITMLDAQQLSKSYTLAGKRTINILQGVTLRVHEGEMVTIVGASGSGKTTLLNLLGTLDTPDSGTIVFNNQPLFQNNRYTLSRKALAAFRNRQIGFVFQFHHLLSDFTALENVAMAEFIATGNLQAAKVRAAELLTNFGLSERLDHLPSELSGGEQQRVAIARALMNNPKLVLADEPSGNLDQRNSQLLYELMARISKEQRTAFIIVTHNYDYAAMADRCFCMENGLLGEYKSYEKSTAV
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PYRE_CLOBL
Sequence: MSNINVIDILKESDALLEGHFLLSSGRHSNRYCQCAKLLQCPQKSEKVISVIAEKLKEVDFNIIVGPAMGGVIVSYELARQTNKPGIFAERKEGVMCIRRGFEIKKGDKVIISEDVVTTGKSSLEVAKVIEEMGGEVVGIACIVDRRAEDVKTNYPIYSACKLEIETYEKDNCELCKKNIPFVKPGSREQK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: NUDL_ECO7I
Sequence: MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDTSVIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYSASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: RTF2_PIG
Sequence: MGCDGGTIPKRHELVKGPKKVEKVDKDAELVAQWNYCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSSEKALGKAASHIKSIKNVTELRLSDNPAWEGDKGSTKGDKHDDLQRARFICPVVGLEMNGRHRFCYLRCCGCVFSERALKEIKAEVCHTCGAAFQEDDVIVLNGTKEDVAMLQTRMEERRLRAKLGKKTKKPKAAESVSKSDISEEAPGPSKMKAGKPEETSLDSREKKTSSAPRSAAAHGSSSGKAGKPVCGAPKRSIADSGESEAYKSLFTTHSSAKRSKEESAHWVTHTSYCF
What is the function of this protein?
Replication termination factor which is a component of the elongating replisome.  Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication.  Might function to facilitate fork pausing at replication fork barriers like the rDNA.  May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion.  Interacts with nascent DNA.
What are the official names of this protein?
Replication termination factor 2, RTF2, Replication termination factor 2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the rtf2 family.
What are the subcellular locations of this protein?
Chromosome. Note=Localizes at the replication fork.
Protein: PSIE_ECOLI
Sequence: MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLADVLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLIIVDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: REXO5_MACFA
Sequence: MEPEREGTERHPRKVRKRRQAPNKLVGAAEAMKASWDLEESQPEAKKARLSTILFTDNCEVTHDQLCELLKYAVLGKSNVPKPSWCQLFHQNHLNNVVVFVLQGMSQLHFYRFYLEFGCLRKAFRHKFRLPPPSSDFLADIVGLQTKQRVGDLPKTMEGPLPSNAKATINLQNDPIIQKYGCKKVGLTRCLLTKEEMRTFHFPLQGFPECENFLLTKCNGSIADNSPLFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVTTKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKAILGKDIQCPDRLGHDATEDARIILELAQYFLKYGPKKIAELNLEALANHQEIQAAGQEPRNTTEILQHPNTSVLECLDSVGQKLLFLTRETDAGELASSRNCQTIKCLSNKEVLEQARVEIPLFPFSIVQFSFKAFSPILTEEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETRQPHLCIQYEVLEAAQLAIESLDGILVDGTCIKVQRPVTELTLDCETLVNELEGDSENQGSIYLFGVSETFKEQLLQEPRLFLGLGAVILPKDLKNGKQKKYCFLKFKSFGSAQRALNILTGKDWKLKGRHALTPRHLHAWLRGLPPESRRPAGLRVVPPPFEQEALQTLKLDHPKIAAWRWGRKIGKLYNSLCPGTLCLILLPGTKSTHGSLSGLGLMGIKEEEESTISGL
What are the official names of this protein?
RNA exonuclease 5, Putative RNA exonuclease NEF-sp.
Protein: GP64_HETPA
Sequence: MNKFITLFVLLASVSVAMSATCLTCVKEGAVCDATANICEEGTVCIKPNSTAANTICFVLPTLNEDCSGPLACADSYYCNTTSKICVEAYYLGVGESCSSENQCSTSLVCTGGKCVNEVYPLCGASNSRVGCKAGEGCAFNGTALVCSPFIANGAACNTSTSGLCHPVSSCSNGVCTAPLTGALNSNCTSNTDCNIANGLYCSSGKCTAVPEALNNCTTTPTVDNCLGYSACMCPSNDDTAKTGSCKDTIEYSDVTSDAYNKYDSCVVSCPAVTIVQKQSCLSKCTNPLAGAANNVCSSATTIAFNAFVVFAIVLSVLLF
What is the function of this protein?
Cell-cell adhesion during development.
What are the official names of this protein?
Cell-cell adhesion glycoprotein 64, Gp64, Contact site 1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the membrane by a GPI-like-anchor that contains a phosphoceramide group.
Protein: ERA_SALDC
Sequence: MSTDKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGPYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: THIC_VIBVU
Sequence: MSNRKQARLEAKQFIDTLSVQPYPNSTKVYVEGSRSDIRVPMREISLADSLVGGTKEAPIFQPNEAVRVYDTSGVYTDPTHQIDLYNGLPKLREEWIAERADTEVLDDVSSVYTKERLEDETLDELRYGNLPRIRRAKAGYCVTQLHYARKGIITPEMEYIALRENMGRAKYQDEVLTQQHAGQSFGANLPKEITPEFVRREVAEGRAIIPSNINHPESEPMIIGRNFLVKVNANIGNSSVTSSIEEEVEKLVWSTRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLTWEVMRDTLIEQAEQGVDYFTIHAGLLLRYIPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSIADANDEAQFAELRTLGELTKIAWEYDVQVIIEGPGHVPMHMIKENMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKEDVKTGLITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLSLDPDTARAFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKGQQGEAGQAIEVKLLDDPLEGMKQKSAEFKASGSELYHPAVSHEEVAEG
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ARLY_BURO1
Sequence: MTSQLHKKGEAWSARFSEPMSELVKRYTSSVFFDKRLALVDIAGSLAHANMLAAQKIINADDLAAIERGMAQIKGEIERGEFEWQLDLEDVHLNIEARLTALIGDAGKRLHTGRSRNDQVATDIRLWLRGEIDRIGGLLNDLRGALIDLAEQNADTIMPGFTHLQVAQPVTFGHHLLAYVEMFTRDAERMRDCRTRVNRLPLGAAALAGTSYPIDRHAVAKTLGFDGICANSLDAVSDRDFAIEFTAASALVMTHVSRFSEELVLWMSPRVGFIDIADRFCTGSSIMPQKKNPDVPELARGKTGRVNGHLMALLTLMKGQPLAYNKDNQEDKEPLFDTVDTVADTLRIFAEMVAGITVKPDAMRAAALQGFSTATDLADYLVKRGLPFRDAHEAVAHAVKICDDRGIDLADLTLDEMKQELPNVAHLIGDDVFGYLTLEGSVASRNHPGGTSPDQVRAAVKAARAALAK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
Protein: CLF1_USTMA
Sequence: MSRSAPRIKNRAPAPIQISAEQLLREAQERQEAPASAPVQKIEDYEELEEYRGRRRSEFEDRLRRNGLNMSTWIKYASWEASQGEMDRCRSIYERALDVEPHHLPLWLRYTEQELKMRNVQHARNLYDRAVSILPRIDQLWYKYVHLEELLGNIPGTRQVFERWMKWEPEEKAWHAYINLEVRYDELDRASAIWERCVTCHPVPKQWIRWAKFEEDRGNLEKARIVFQMALDYIGEDEDAMEKAQSVFTAFAKMETRLKEYERARVIYKYALERLPRSKSEGIYSSYTRFEKQFGTMNSVEDTVIGKRRIQYEEELAAQEAGGAPADYDTWFDYSRLEEDAYRALLATGGSQDQLQQAVKRVREVYERAIAQVPSSQEKRDWRRYIFLWLRYALFEEIDTRDYDRTREIYKAAIALVPHRRFTFAKLWVQYARFEVRRLELTAARKILGAAIGMAPKLKLFSSYIELEVSLKEFDRARKIYEKALEWDPTNSQTWVRFAELEKNLFDTDRARALFELGVGQAEGGEASGGLDMPEIVWKAYIDFEFEEREWEKVDALYERLLAKSGHVKVWISYALSKINRATAIEEDEDEEDDDHDHDDDMAATPSRELTEEEEALRQQRRSALASSAREIFQRAYDNLKSRSLKDERVALLESWKSFEQQHGSAETLSRVEAKFPRVVKKRRQVEDSADGAMEEYYDLIFPDDQDEGKGAFKLLQMAHAWRAAQAAKEQQQQQQQSSSAETGASASAGAGATGDDVRDEESIGIAIDDDQEQDASGEEA
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle progression.  Required for the spliceosome assembly and initiation of the DNA replication (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor CLF1.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZN346_XENTR
Sequence: MADEFGDGDTVELPVGKEAVDALIRENSHIFSDTQCKVCSAVLISESQKLAHYQSRKHANKVRRYMSIHQGEEFVSAKKFKAAPAESSDGDDRSKCCPICNMTFSSPVVAESHYSGKTHIKNLRLREQGGVTEGMLHQAKKLVVTRTPTIATKIDNRMDQSDPTKFCKLCHATFNNPLMAEQHYAGKKHKKQETKTQLMTIYTSSGHTPAQAPIAINVNSPLPGSGSAGKGFSCDTCNIVLNSIEQYQAHVSGAKHKNQLMSMTPLSKEGPPAAGGPSALAGPPSTGGALSSGGPSARGFSASGGPTPKGPSSFGGLPPMGGLMPPPYPPPHSQPYVREDMMGPDGYTYFNKDF
What is the function of this protein?
Binds preferentially to dsRNA, but also to RNA-DNA hybrids.
What are the official names of this protein?
Zinc finger protein 346, Just another zinc finger protein, Protein jaz.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Primarily nuclear.
Protein: ENGB_RHOPB
Sequence: MTQDNDAKFIEQGRKLFAGDWQFIWASPSIETLPPMAGLEVAFAGRSNVGKSSLINALTGRNALARTSHTPGRTQELIFFEGPENANFRLVDMPGYGYASAPKAKIASWTSLIHNFLQGRSTLARVYVLIDARHGLKEVDQDVLNTLDKSAVSYQVVLTKADQVKPAELAQCRIDVEAGLRKHPAAYPELLVTSSRTGAGMPELRAAMIKLIAERS
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ALL1_HORSE
Sequence: MKLLLLCLGLILVCAQQEENSDVAIRNFDISKISGEWYSIFLASDVKEKIEENGSMRVFVDVIRALDNSSLYAEYQTKVNGECTEFPMVFDKTEEDGVYSLNYDGYNVFRISEFENDEHIILYLVNFDKDRPFQLFEFYAREPDVSPEIKEEFVKIVQKRGIVKENIIDLTKIDRCFQLRGNGVAQA
What are the official names of this protein?
Major allergen Equ c 1.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUB_STRPD
Sequence: MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVGVLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVDQTMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISQFERTSPLNFTEDDLCRFSFKVACSKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEIADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKVIAILEKRDQEYKPKKVLI
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: FUR_YERPE
Sequence: MTDNNKALKNAGLKVTLPRLKILEVLQNPACHHVSAEDLYKILIDIGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSNESIESLQREIAKQHGIKLTNHSLYLYGHCETGNCREDESAHSKR
What is the function of this protein?
Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLI15_YEAST
Sequence: MDWAIKAARKKTQRKPGSTRSIIETLDDLNNLTTDAHSEINQRLYESSEWLRNNVYMNTLKYEDKKMEESLISPENTHNKMDVEFPKMKGEYELSNSQNDAAKDVTKTPRNGLHNDKSITPKSLRRKEVTEGMNRFSIHDTNKSPVEPLNSVKVDANESEKSSPWSPYKVEKVLRESSKTSESPINTKRFDNQTWAAKEEMENEPILQALKKAESVKVKPPPNSGIARSQRRSNMFVPLPNKDPLIIQHIPPTKSSGSIPKVRTVKESPIAFKKKSTINSPAIRAVENSDTAGSTKASSVFDRLSSIPTKSFENKISRGNVGHKYSSSSIDLTGSPMKKVSQKFKSINSTDTDMQEALRDIFSVKNKITKNNSPKGKNSRKSSIPRFDKTSLKLTTHKKLAIIAEQKKKSKHSSDVHKTGSRPHSISPTKISVDSSSPSKEVKNYYQSPVRGYLRPTKASISPNKNKNLTTSQTPHRLKIKEKTLRKLSPNIADISKPESRKSKNYRLTNLQLLPPAEAERDDLKKKFDKRLSGIMRSQQEHHRRKQEKQKRMSHLEQDLKKQTSFSNDYKDIRLKESLAPFDNHVRDTINKNTAFSTDNILATINTVDHREIIGNVTPKIASVNDSLPEINTDSEDEASVTLAAWAKSPYLQEQLIRQQDINPQTIFGPIPPLHTDEIFPNPRLNRLKPRQIVPKRS
What is the function of this protein?
Required for high-fidelity chromosome segregation during the later part of each cell cycle in association with the protein kinase IPL1.  Stimulates IPL1 kinase activity and facilitates its association with the mitotic spindle.  Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles.
What are the official names of this protein?
Inner centromere protein-related protein SLI15, INCENP-related protein SLI15.
What is the protein family that this protein belongs to?
Belongs to the INCENP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore (PubMed:11724818).
Protein: DSBE_SALTI
Sequence: MKRNVLLLPLLIFLLIAAALLWQLARNAQGDDPTNLESALTGKPVPAFRLESLETPGQYYQAEVLTQGKPVLLNVWATWCPTCRAEHQYLNRLAAQGIRVVGLNYKDDRAKAVAWLKELGNPYALSLSDSDGMLGLDLGVYGAPETFLIDGRGIIRYRHAGDLNARVWESELKPLWDRYSREAAQ
What is the function of this protein?
Involved in disulfide bond formation.  Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme.  Possible subunit of a heme lyase (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbE, Cytochrome c biogenesis protein CcmG.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: KAX3V_MESMA
Sequence: VGKNVICIHSGQCLIPCIDAGMRFGICKNGICDCTPKG
What is the function of this protein?
Blocks voltage-gated potassium (Kv) channel and augments neurite extension via NGF/TrkA signaling pathway.
What are the official names of this protein?
Toxin BmK NSPK, Buthus martensii Karsch neurite-stimulating peptide targeting Kv channels.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: THIM_STAS1
Sequence: MNSLNNLRTNNPLVICYTNDVVKNFTANGLLSLGASPAMSQAPEEAIDMLTPANALLINIGTLTKDREQDILEIAKTANEVGTPIVFDPVAVGASQYRKDFCKTFLNTVDVVVIKGNASEILALINNDAKMKGTDSDDNLNAIEIAKEAHKRLNSAIIITGKEDVVIQDNQIYQLNNGSALLAKVTGAGCLLGAVIASFLPTDETTSISQLVEATSIYNIAAEKAEQLAEDKGPGTFMTLLLDALYQVTYDDYSNQSDIQEVQ
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: YHPR_THAAR
Sequence: CGRRRGSLAWPDASSPSANPRPGAGAAESSACTTSGWSRWRTSLLVAGALLGLQWLPQLAGLWVACFGFGTGACIILALMFMGLRTENPRQAAALSGMAQCVGYLLAAFGPPLVGGLRDRSQDWNPALTVCLVLSLTMAAAGMLAGRNRRIRSASTAASTPAAG
What is the function of this protein?
May be involved in uptake of anionic 4-hydroxy-benzoate.
What are the official names of this protein?
Putative anionic 4-hydroxy-benzoate permease.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TPIS_PELPB
Sequence: MRRKIVVGNWKMNNSVAESVQLATDVLAALGEGFSGCEVGIAPTYLALDATEKVIAESEVQLVAQNCHYENDGAFTGEVSARMILAVGCSSVIIGHSERRQYFGETNATVNLRIKKALSEGLNVILCVGETLAERESGVMETVISSQVREGLDGIIDISAIVIAYEPVWAIGTGKTASSAQAEEVHLFIRTLVTGLYGQTASEKVRIQYGGSVKPSNAAELFAMPNIDGGLIGGASLNADDFAAIVKAASV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSTP_STASI
Sequence: MKKTKNNYYTRPLAIGLSTFALASIVYGGIQNETHASEKSNMDVSKKVAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKALVQNRTALRAATHEHSAQWLNNYKKGYGYGPYPLGINGGMHYGVDFFMNIGTPVKAISSGKIVEAGWSNYGGGNQIGLIENDGVHRQWYMHLSKYNVKVGDYVKAGQIIGWSGSTGYSTAPHLHFQRMVNSFSNSTAQDPMPFLKSAGYGKAGGTVTPTPNTGWKTNKYGTLYKSESASFTPNTDIITRTTGPFRSMPQSGVLKAGQTIHYDEVMKQDGHVWVGYTGNSGQRIYLPVRTWNKSTNTLGVLWGTIK
What is the function of this protein?
Lyses staphylococcal cells by hydrolyzing the polyglycine interpeptide bridges of the peptidoglycan.
What are the official names of this protein?
Lysostaphin, Glycyl-glycine endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M23B family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQGE_SHISS
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: YCF3_NEPOL
Sequence: MPRSQRNDNFIDKTFTVVADILLKVLPTTRREKEAFTYYRDGMSAQAEGEYAEALQNYYEAMRLEVDAYDRSYILYNIGLIHTSNGEHAKALEYYYQALERNPYLPQALNNIAVIYHYRGEQAIESGNSRISNLLFDKAADYWKEAIRLAPTNYIEAQNWLKITNRLEEAI
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3, RF3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RAB6A_CAEEL
Sequence: MADFTNNALKKFKLVFLGEQSVGKTSIITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTTKWVDDVRNERGCDVIIVLVGNKTDLADKRQVSTEDGEKKARDLNVMFIETSAKAGYNVKQLFRKIATALPGIVQEETPEQPNIVIMNPPKDAEESQGRQCPC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:22992455, PubMed:26891225).  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:22992455, PubMed:26891225).  In its active GTP-bound form, acts redundantly with rab-6. 2 (in its active GTP-bound form) to positively regulate the retrograde trafficking of cargo molecules from endosomes to Golgi structures (PubMed:26891225).  Required for the retrograde trafficking of glr-1, a subunit of AMPA-type glutamate receptors (AMPRs), out of early endosomes and into the Golgi compartment in neurons (PubMed:26891225).  Together with rab-6. 2, promotes the retrograde trafficking of mig-14 from endosomes to Golgi structures in the intestine (PubMed:26891225).  In oocytes, in its active GTP-bound form, involved in the membrane fusion and exocytosis of secretory vesicles (cortical granules) to play a role in the remodeling of the embryo surface following fertilization (PubMed:22992455).  Recruits sep-1 to cortical granules (derived from the Golgi complex) for exocytosis during the oocyte-to-embryo transition (PubMed:22992455).  Required for seam cell division and alae formation (PubMed:33826611).  Promotes spontaneous reversals in locomotion (PubMed:26891225).
What are the official names of this protein?
Ras-related protein rab-6.1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendrite. Perikaryon. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle. Note=Following fertilization, localizes to cav-1-positive vesicles tethered to the plasma membrane (PubMed:22992455). Localization becomes dispersed throughout the cytoplasm once the vesicles fuse with the plasma membrane during meiotic anaphase I (PubMed:22992455). Temporarily co-localizes with sep-1 in the cortical granules prior to membrane fusion (PubMed:22992455). Co-localizes with rab-11.1-positive vesicles near the plasma membrane until vesicle exocytosis in embryos (PubMed:22992455). Co-localizes with rab-6.2 at vesicular structures throughout the oocyte cytoplasm (PubMed:22992455). Co-localizes with rab-6.2 in neuronal cell bodies and dendrites and in Golgi structures in neurons and the intestine (PubMed:26891225). Co-localizes with vps- 52 at Golgi structures (PubMed:21613545).
Protein: WNT8B_DANRE
Sequence: MFMHLEVYYYAFILMAHMKTCCGWSVNNFLMTGPKAYLIYSSSVAAGAQSGIEECKYQFAWDRWKCPERALQLSTHSGLRSANRETAFFHAISSAGVMYTLTRNCSLGDFDNCGCDDTRNGQRGGQGWLWGGCSDNVGFGEVISKQFVDALETGQDARAAMNLHNNEVGRKAVKGTMQRTCKCHGVSGSCTTQTCWLQLPEFREVGNYLKEKYHRAVKVDLLRGAGNSAASRGAIAETFNSISRKELVHLEDSPDYCLENRTLGLPGTEGRECLRKGKNLSKWEKRTCKRLCGDCGLAVEERRAETVSSCNCKFHWCCAVKCEQCRKTVTKYYCVKRSKRVKNDNASRRKSYRLKKKH
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.  May play a role in the establishment of polarity in the nervous system.
What are the official names of this protein?
Protein Wnt-8b.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.