PharMolix/UniProtQA huggingface dataset:
Protein: MRFL_MOUSE
Sequence: MDVLGENEALQQFFEAQGASGTLENPALDTSLLEEFLGNDFDLGALQRQLPDTPPYSASDPRSPPQVKGACCRTPRPPAGRIPAAFLHSTTAPGPLPEHPSQSMAGQTHSSFQNGYPESSHPATCRHQTGPSRLGTSCSFHQQPLCHVPGSSLPPTKKRKHSQIQEDSWDCSSWAHYFRPMTTRSQSIEVQDHDREGRNGMPVDQCSPALKWQPYQSVPWHSLLNSRYEKLPEVGYQVVTDKGFTFSPVDEAFVCQKKNHFQITVHIQVWGSPKFVKTQVGLKPIEKFYLKAFGIKVEATNQVIAIEQSQADRSKKTFDPVKIDLLTDQVTKVTLGRLHFSETTANNMRKKGKPNPDQRYFMLVVGLYAANQDQFYLLAAHISERIIVRASNPGQFENDSDALWQRGQVPESIVCHGRVGINTDTPDEALVVCGNMKVMGTVMHPSDSRVKENIQEVDTNEQLRRIAQMRIVQYDYKPEFASAMGINTAHQTGMIAQEVQEILPRAVREVGDVTGGNGETLENFLMVDKDQIFMENVGAVKQLCKLTNNLEERIEELEIWNKKLARLKRLSSSWKSSISEASSISKLSRAVSASSARRTGSKKPTKVSFSGRKQSCPNWVFQTLVVVLIAVMAFCALTIVALYILSLKDQDRRSPNLPLSNMTSSPEPALSSTAPTSAPHTTPETTQTSLQVPEITFCEILPCQETYCCPVWGPRILFSSPAQRQLEAEREIHQRQWAEDKSKSFLTSSALISPDWESDWIDTTIASIQIVEIQQMIDRRYCSRMLHCGPGHYNYNIPVNKNTPTNVKFSLEINTTEPLIVFQCKYTLGNICFRSQRERTQSDGEDAQMTQGYQHIWRLPVARFSDSAYHFRVAAPDLADCSTDPFFAGIFFTDYFFYFYRRCN
What are the official names of this protein?
Myelin regulatory factor-like protein.
What is the protein family that this protein belongs to?
Belongs to the MRF family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FRIHB_XENLA
Sequence: MQSQVRQNFNSDCEAAINRMVNLEMYASYVYLSMSYYFDRDDVALHHVAKFFKEQSHEEREHAEKFLKYQNKRGGRVVLQDIKKPERDEWSNTLEAMQAALQLEKTVNQALLDLHKLASDKVDPQLCDFLESEYLEEQVKAMKELGDYITNLKRLGVPQNGMGEYLFDKHTLGESS
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).
What are the official names of this protein?
Ferritin heavy chain B, Ferritin H subunit B, Ferritin heavy chain 1.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: RNH2_FRACC
Sequence: MRHYGVALRRDAGLFGYERALNRHGLGPVAGVDEAGRGACAGPLVIAAVILAPEARQRLARLADSKLLTEQIRESVFEDVMAAAAAWSTVVISAAEIDRVGLHVANITGMRRAVARLSARPGYVLTDGFAVAGFGVESLAVVKGDRVVACVAAASVVAKVTRDRIMRALHTRYAEYDFAQHKGYVTAAHAAALARCGPCDEHRMSYVNVAAHAATTREARSLRLEDRVLVTSRHGVTETV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_KLEP3
Sequence: MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANP_ALIF1
Sequence: MVTDNKTADASFESLLRIFTVPEAPDSTLGIIEKELSQNLNQFLREHIVAEEKPLTEIEKDFTDSSMPESPTYVSEHTEHLLDTLVSQSVHTSAPSFIGHMTSALPYFLMPLSKIMIALNQNLVKIETSKAFTPLERQVLGMLHRLIFGQKDSFYQHWMHSADHSLGAFCSGGTIANITALWVARNRLLKPEGDFEGIAKQGLFAALMHYKCNGLAIFVSERGHYSLKKAADVLGIGQDGVIAVKTDNNNRVCLDDLELKIAQAKAKNIKPLAIVGVAGTTETGSIDPLRELANVAQREGCHFHVDAAWGGATLMSNTYRHLLDGIDLADSVTIDAHKQLYVPMGAGMVIFKDPELMSSIQHHAEYILRKGSKDLGRHTLEGSRSGMAMLLYSCFNVISRPGYELLINQSIEKAHYFADLIQQQDDFELITEPELCLLTYRYVPSNVKAALAIATDEQKIEIYEHLDNLTKYIQKTQRETGKSFVSRTRLTPEAYQHQPTIVFRVVLANPLTTKEILQNVLIEQREIASSSEISLPLLNQIVGNILH
What is the function of this protein?
Catalyzes the pyridoxal-dependent decarboxylation of aspartate to produce beta-alanine.  Has weak activity with glutamate.
What are the official names of this protein?
Aspartate 1-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: HUTG_KLEP3
Sequence: MMLWQATPASLWQGRDDSAEAPNALRLFQTIARAERFAPQEMPGDIALLGFACDEGVRRNKGRTGAGHGPEALRRALANMASHQGHDRCVDMGTISVDGEQLEAAHQALREAVAACQRAGKRTLVLGGGHETAFGHGAGVLDAFPGEKVGIINLDAHLDLRFAECASSGTPFRQLALECDAQQRGFHYTCIGVSRAANTQALWDEAARRQVAVVEDLAVLADFDTHVLPELERNIAQYDRLYLTIDLDVLPAREMPAVSAPAALGVPLAILLRIVEPLCRSGKLQAVDLVEFNPQFDIDGQGARAAARLAWQIAHWWR
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: Y812_AQUAE
Sequence: MEEILIWIKKLEKYLYALNAKVAGIPLYKIIIASAIMLFTLILRRLIAFLIVKILTKLTIRTKTDVDELIVKAFVKPFSYFIVVFGFYLSLLVLEVPKVYADKFLKTFSLLILGWAIIRFLNLFHNKIVEFFVKVGGKDFAEEVGDFILKILKAFVVVIVGASLLQEWGVNIGAILASVGLLGLAVSLAAKDTFENILSGLIILLDKPVKVGETVKVKDFMGSVEDIGLRSTKIRTFDKSLVTIPNRDIVNNHVENFTRRNKRRVRFYIGVVYSTKREQLENILKEIRELLKEHPGVAKDEKFYVYFENYGDSSLNILIQYYANTNDYEEYLKIIEDINLKIMEIVEKNGSSFAFPSRSVYIEKMPKS
What are the official names of this protein?
Uncharacterized MscS family protein aq_812.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRE_CAMC1
Sequence: MDLEKIYKDAGAYLEGHFLLSSGNHSQFYLQSAKVLEDPALAGKLADELAAVIEKFGIKFDSVCSPALGGILAGYELARAAKKRFIFTERVEKVMSLRRGFEVKKGEKFIVCEDIITTGGSALEAAHVIESLGGEVVGFAALANRGFCKVANLGNDSKPNAKLPSDKPFFALGNFEFEIYEPEHCPLCKSGSKAIKPGSRGN
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: PSBF_SOYBN
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CRCB_METRJ
Sequence: MSFTTCILVMIGGALGTLARYVVSVLSLPISRDLPWGTILINVTGSFIIGLFGTLTLAQGRFPVSENVRLFVMIGLCGGYTTFSSFSLQTLDLMRNGAVVRAMVNVCASVVLCVLAVALGHVVAAHWNGGAVQIAQVSIEEDG
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MIAB_SHESH
Sequence: MSKKLHIKTWGCQMNEYDSSKMADLMDEYEGYTLTEEASEADVLLLNTCSIREKAQEKVFHQLGRWKKLKEKNPDLIIGVGGCVASQEGKVIKERAQCVDLIFGPQTLHRLPEMIDQIRDGGKAVIDISFPEIEKFDKLPEPRADGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPLDDIILEIAQLADQGVREVNLLGQNVNAYRGATHDDEICTFAELLRYVAAIDGIDRLRFTTSHPIEFTQDIIDVYEDTPELVSFLHLPVQSGSDRILTQMKRGHMAIEYKSIIRRLRKARPDIQISSDFIIGFPGESKQDFADTMKLIEDVQFDHSFSFIYSARPGTPAADLPDDVTLAEKKERLAILQDRITQQAMRYSRQMLGTVQRILVEGPSVKNPMELRGRTETSRVVNFEADPKHIGSFVDVEIVDVYTNSLRGTFVRGEDEMDLRRSLTPSDILAKHKKDDDLGVTQYIP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_DRIGR
Sequence: MKNVTDSFVSLGHWSSAGSFGLNTDILATNPINLSVVLGVLIFFGKGVSDLLDNRKQRILSTIRNSEELRGRAIEQLEKARARLRKIGMEADEFRVNGYSEIEREKENLINATYNNLERLENFKNETIRFEEQRAINQVRQRVFQQALQGALGTLNSCLNSELHLRTISANIGMLGTIKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: EV45_PSHV1
Sequence: MRPNGARTQTAPPPAAAEGTADVHGNGEAATIQLDGQPSAPSPPLTTVFEATDDYKARRRNLESEPPFEVRAILDDELSDYPVAAPLDAVPQKHSCCCGVCLRRCAFVLTGMAVGMLLAAALLATIAAFAVPESVWTGGVCERGWVQHMGVCYKPGRTPPPSSAADGNFSAATFAGANTNCAAAGGSIVSSDQALSFLVLLSKTASGPNSAPPRGSWWTTHSGSCAIVHYAPSSTLEVYGNTSSLQSLALRTRDALDVSIAEDTQCSGSAGVMCAAAPAPPTALKYAQALRAILTLGVRAE
What is the function of this protein?
Seems to be required for glycoprotein B-induced fusion.
What are the official names of this protein?
Envelope protein UL45.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae HHV-1 UL45 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Note=In transfected cells, it is retained within the ER.
Protein: RECF_STRP7
Sequence: MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIYFLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQARLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQRNTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEELSISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFGSQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTFITTTSLDHLQNLPENLSIFTIQDGKASVNGN
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_DROMD
Sequence: MTIRPAYRPKIIKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHNVRELEVLLMQNRIYCGEIAHAVSSKKRKEIVERAKQLSIRLTNPNGRLRSQENE
What are the official names of this protein?
60S ribosomal protein L32, Ribosomal protein 49.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: RFP_DISSP
Sequence: MRSSKNVIKEFMRFKVRMEGTVNGHEFEIEGEGEGRPYEGHNTVKLKVTKGGPLPFAWDILSPQFQYGSKVYVKHPADIPDYKKLSFPEGFKWERVMNFEDGGVVTVTQDSSLQDGCFIYKVKFIGVNFPSDGPVMQKKTMGWEASTERLYPRDGVLKGEIHKALKLKDGGHYLVEFKSIYMAKKPVQLPGYYYVDSKLDITSHNEDYTIVEQYERTEGRHHLFL
What is the function of this protein?
Thought to play a role in photoprotection of the coral's resident symbiont microalgae's photosystems from photoinhibition caused by high light levels found near the surface of coral reefs.  In deeper water, the fluorescence may be to convert blue light into longer wavelengths more suitable for use in photosynthesis by the microalgal symbionts.
What are the official names of this protein?
Red fluorescent protein drFP583, DsRed.
What is the protein family that this protein belongs to?
Belongs to the GFP family.
Protein: Y818_METJA
Sequence: MKLTEKNITLFALTCFVIISTTWLFLNPIQPKEKHIAEIKEGDYVVIKGYIQEMYVKRDKYRHVINISRIVINDGTGNLDVVAFGKTREELLTYILSYNPMIKEGDYIEVKGRVTLYKGKYEIILNNIKDFKLLKKNNFERDIYLSPTPTGIYASKYGKKYHTSKNCPYGKRLKEENIIYFYSEDDAKALGYEKCKWCEEHGG
What are the official names of this protein?
Uncharacterized protein MJ0818.
Protein: CCSA_PROM3
Sequence: MFGVTLAELSASLGDPVLALGLAAFALLLLAIPISFWMVSGGSNSAVVTLLVALANLVLTAQLVLRWWQSGHFPISNLYESLCFLAWACTLAQLLVERSLSSPIVSAAATPMALLCVAFASFALPETLQEASPLVPALRSSWLVMHVSVIMCSYAALLVGSFLSMAVLFTDRQQTLELRSSSIGTGGFRQAKLATSAIDQNDGLRLSSINLSRTEQLDSLSYRTITVGFLLLTLGLISGAVWANEAWGSWWSWDPKETWALICWMVYAAYLHTRFSRGWSGRRPALVAVAGIVVIVVCYIGVNLLGIGLHSYGWFFEA
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PCP_STAS1
Sequence: MRILITGFDPFGGERVNPALEAVKLLPDEIGAHKIDKLEIPTVFHKSKDVILSQMKRYEYDIVLAIGQAGGRYELTPERVGINVDDARIADNEGNQPIDEVIQVDGNAAYFSNLPVKRITEAIKAQGIPSRLSNTAGTFVCNHILYQLGYLQATAFPKIKFGFIHVPFVPEQVTDKPEKPSMSLETIRIGLYAALEAIVESGEDIKVALGETH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP1M1_ARATH
Sequence: MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting at the trans-Golgi network and early endosomes (TGN/EE).  The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.  Functions redundantly with AP1M2 in multiple post-Golgi trafficking pathways leading from the TGN to the vacuole, the plasma membrane, and the cell-division plane.
What are the official names of this protein?
AP-1 complex subunit mu-1, Adaptor protein complex AP-1 subunit mu-1, Adaptor protein-1 mu-adaptin 1, Adaptor-related protein complex 1 subunit mu-1, At-muB1-Ad, Clathrin assembly protein complex 1 mu-1 medium chain, Mu1-adaptin 1.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GRM_MICRO
Sequence: MTTSTGDDRIDQLQQAITKSRRYQTVAPATVRRLARAALVASRGDVPDAVKRTKRGLHEIYGAFLPPSAPNYTALLRHLDSAVEAGDDEAVVRWDRRAMSVHMSTRERVPHLDEFYREIFRHVPRPNTLRDLACGLNPLAVPWMGLSDETVYVASDIDARLMDFVGAALTRLGVAHRTSVVDLLEARLDEPADVTLLLKTLPCLETQQRGSGWEVIDIVNSPIIVVTFPTKSLGQRSKGMFQNYSQSFESQASERSCRIQRLEIGNELIYVIHK
What is the function of this protein?
Specifically methylates the N(7) position of guanine 1405 in 16S rRNA (By similarity).  Confers resistance to aminoglycosides.
What are the official names of this protein?
16S rRNA (guanine(1405)-N(7))-methyltransferase, 16S rRNA m7G1405 methyltransferase, Gentamicin-resistance methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Aminoglycoside resistance family.
Protein: FOLD2_COLP3
Sequence: MRASLIDGKAIAKKLRDSVKEEVNLRISNGQRVPGLAVILVGCDPASQVYVGSKRKACEEVGFISRSYDLPHTTSEQELLALVSELNNDDSIDGILVQLPLPKNLNADLIIEHINPLKDVDGFHPSNVGKLVLRQPGLRPCTPKGIVTLIESTGIDPKGLDALVIGASNIVGRPMGLELLLAKCTVTTTHRFTKDLEGKVRNADLLVVAVGKPGFIPGEWIKEGAIVIDVGINRLDNGKLVGDVDFGAAKERASFITPVPGGVGPMTVASLIENTLIACQQSSQ
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 2.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SAM50_YEAST
Sequence: MTSSSGVDNEISLDSPMPIFNESSTLKPIRVAGVVTTGTDHIDPSVLQAYLDDTIMKSITLGQLVKNADVLNKRLCQHHIALNAKQSFHFQGNTYISDEKETHDVVPLMEVVSQLDILPPKTFTAKTGTNFGNDNDAEAYLQFEKLIDKKYLKLPTRVNLEILRGTKIHSSFLFNSYSSLSPQSILNLKVFSQFYNWNTNKGLDIGQRGARLSLRYEPLFLHKLLHNPHSNESPTLFHEWFLETCWRSTKICSQGTSAPYMYSGTMLSQAGDQLRTILGHTFVLDKRDHIMCPTKGSMLKWSNELSPGKHLKTQLELNSVKSWMNDDFITFSTTIKTGYLKNLSSQQSLPVHICDKFQSGGPSDIRGFQTFGLGPRDLYDAVGGDAFVSYGLSVFSRLPWKKVEKSNFRLHWFFNGGKLVNHDNTSLGNCIGQLSKEHSTSTGIGLVLRHPMARFELNFTLPITAHENDLIRKGFQFGLGLAFL
What is the function of this protein?
Component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex.
What are the official names of this protein?
Sorting assembly machinery 50 kDa subunit, TOB complex 55 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SAM50/omp85 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: FRSA_SALNS
Sequence: MTQANLSETLFKPRFKHTETSTLVRRFNRGSQPPMQSALDGKNVPHWYRMINRLMWIWRGVDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWAKQAMDWQQKACQEQDAMRSGRYWLHASTLYNIAAYPHLKGDELAEQAQALANRAYEEAAQRLPGSLREMEFAVPGGSPVTAFLHMPKGDGPFPTVLMCGGLDAMQTDYYTLYERYFAPRGIAMLTLDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLEAPRLKAVACLGPVVHALLSDPQRQSTVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGFWKNDPFSPEEESRLITTSSSDGKLIEIPFNPVYRNFDRALQEITDWINHRLC
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: REG2_YEAST
Sequence: MTLSNCDSLDNLFQDPPEEEESSKFVEAVRTLMNRNDMGYPPAAANGTYCLKKIKSLNAKQWKINKKRMCMLPAVKKKNFDFHEQRSLILNLNLWKFIKFINCSSKNNYNKNNKHVRSSNNTVKNENVLPLQKHKKVDNDQRLENLFWRSWFKARKRRDIMGKPRERHIKFNDNVEQCIITDEHFIQRLPSTRLNSTDEQRPCSKSELDPCIGNAASKRSFYDYNSVYVASDAIITTAAATAIISSNSGDYQRGHDVRDVPRNVLLQAGETDFSSVLRVDSDLKLSNISHHSPVKPSSTSSHSTFIFESETDTDTDTDAETENDIDAYIDTSIPNLLL
What is the function of this protein?
Regulatory subunit, binds to type-1 protein phosphatase.  Functions with HEX2/REG1 and SNF1 protein kinase to regulate growth.  Might regulate SNF1 directly or indirectly.
What are the official names of this protein?
Protein REG2.
Protein: CPVL_MOUSE
Sequence: MVRAKWKMVVSLILFMVSPGDGLFHAVYRSILVSQSFKGDAGQPLFLSPYIKNGKIKEGQRKSMVSPFPGMNDKSYAGYITVNQTYNSNLFFWFFPARMQPEDAPVVLWLQGGPGGSSMFGLFVEHGPYIITSNMTVVARDFPWTFTLSMLYIDNPVGTGFSFTDHFQGYATSEDDVAQDLYSALIQFFTLFPEYAKNDFYVTGESYAGKYVPALAHYIHSLNPVRKFKIRLKGIAIGDAYTDPESIIGGYAAFLYEIGLLDEQQQKYFQKQCSKCVKYIKEQEWMKAFEILDKLLDGDVTTGSSFFQNVTGCTNYYNILQCTEPKEQSYFAKFLTLPQVRQAIHVGNQNFSDGAEVEKHLREDTVKSVKPWLSEIMNYYKVLIYNGQLDIIVAAALTERSLMAMDWKGSRAYRRARRKVWKIFKSDNEVAGYVRRVGKFHQVIVRGGGHILPYDQPMRSFDMINRFIYDRGWEPYNS
What is the function of this protein?
May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation.
What are the official names of this protein?
Probable serine carboxypeptidase CPVL.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
Protein: MSCL_AGRFC
Sequence: MLNEFKTFIARGNVMDLAVGVIIGAAFSKIVDSVVNDLIMPIVGAIFGGFDFSNYFLPLSSNVNATSLAAAREQGAVFAYGNFLTVLINFLILAWIIFLMVKGVNKLRDSVDRKKIEEKPDAAPPPEDVKLLTEIRDLLKTR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLD_SALTY
Sequence: MNKILLQCDNLCKRYQEGTVQTDVLHDVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFSGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEIDARAREMLHAVGLEHRATHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIFELLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRDGRLTAELSLMGAE
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RSMA_PROM1
Sequence: MGGDNTLNDFRHIPRKRFGQHWLKDQGVLDQIVKAAELNPEDCVLEVGPGKGALTEKLIESQAKFIQAIELDRDLVIGLKKRFNHQNKFSLREGDILSAPLDAENGVTINKVVANIPYNITGPLLKRLIGELRKAPENSFETLVLLMQKEVAQRLLARPGNSNFSALSVRVQLLAKCQDVCDVPSKCFQPAPKVDSKVVMIKPFASIDPDFYEVGNLLEKLLKHAFAGRRKKLRNTIGSFVTSNDQIKEFFAYRGISLDQRPQEISPSNWFGLAKALKETCVIENGTFQSK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMK3_CAEEL
Sequence: MASVPSSSSLPVSHVRRHEDVSTPSAPPTKRSNNQSQPPESYEPNTWLQQQREQEQQKKLAAENIKKQSIEATGNNEMVGEEEEDILSKPCGPHKRRFQFVMIRNITFAIPEGYDVEPNSIEYLGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHHARRIFRETKLLQLMRHDNIICALDIYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRALKYIHSANIIHRDLKPGNLALTDDSDLMILDFGLARSLEKKDTSLTQYVQTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELLTKIENDNSSAIKAVIQSYTTHKRRNFRDVFSAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQHPYLAEFSLPEDEPRADHIFDLDDSQARTRFEWRDAVWKEIMNYKRLSSSPLIPGEADR
What is the function of this protein?
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets (PubMed:11703092).  Involved in axon regeneration after injury, probably downstream of dlk-1 and mkk-4 and upstream of mak-2 (PubMed:21670305, PubMed:19737525).  May phosphorylate mak-2 (PubMed:19737525).  Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis (PubMed:26657059).  Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord (PubMed:27123983).
What are the official names of this protein?
Mitogen-activated protein kinase pmk-3, Stress-activated protein kinase pmk-3, p38 MAP kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Cell projection, cilium.