PharMolix/UniProtQA huggingface dataset:
Protein: ATPI_TRACE
Sequence: MNILSCSTNILNGFYDISGVEVGQHFYWKIGGFQVHGQVLITSWVVIAILLGSAALAVRKPQTIPTGIQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTIFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALLTSVAYFYAGLAKKGLGYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPSVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ISPD_ACTP7
Sequence: MTRKIIAVIPASGVGSRMQAGLPKQYLKLQNKTILEHTLEIFLAHPDIEKIVVAVAETDPFYPQVALLDSPKIQIVFGGETRAHSVFNALQVIEDDSWVLVHDAARPCLKRSDLDKLLQSDAKHGAILATPAIDTMKRADGDKIMHTEDRSTLWHALTPQFFPTHLLKQALISAFEKNLTVTDEASAMEFSGYQPRLIAGRSDNLKITRPEDLALAEFYLTQNTEK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RK20_ANTAG
Sequence: MTRVKRGYVARRRRKNILKLTSGFQGAHSTLFRTANQQGMKSLTSSHRDRGKRKRDFRRLWITRINAAARRSKKSYHTLIQELYKRKILLNRKMLAQIAILDTYCFSTLLGD
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PUM22_ARATH
Sequence: MTHERGYDLASQVLNICNVHHKKLFCHITYRHLLVLSSDDNGCVILKKVITIADDFLKDEFLDLIAQHAHSLSMHDLGISLIQHVLELDFTKKTTQDDKRLHELMAEFDEVLSTSVTADVDKLHKLASKLMLDSDLFFEFVITRRGSLMIQIILGKSEEVDQVILAGVKQRFIDVTTNFYGYRIMIQTIKVFKKRGDLKVYDQILRLIGVHALYLTKDPDMGNKTFQHAINLHHQDCTTFIACGLQSHYIELSFLKHGSKIVEMLIDDRISMVPLVLLMMEIVKCDEDTLVRLATDEYGNNILKKFLALAKEHKEDFFGDLVDKLNPLLDSLRGTLGENIVAIIDSETEMVKDRIVSQGNN
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
What are the official names of this protein?
Putative pumilio homolog 22, APUM-22, AtPUM22.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_STUS1
Sequence: MALLQIAEPGQSPQPHQRRLAVGIDLGTTNSLVAALRSGVTAPLADADGQVILPSVVRYHADRVEVGACAKRAAAADPFNTISSVKRLMGRGLADVKQLGEQLPYRFRQAESQMPFIETVQGAKSPVEISAEILRALRERAEAALGGELVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAVAYGLDRQAEGVVAIYDLGGGTFDISILRLTKGVFEVLATGGDTALGGDDFDHAVADWILQQAGVSEDLAPGEQRELLKIACDAKERLSVDETVQVAYAGWAGELHRETFDALIEPLIARSLRSCRRAVRDSGVELDEITAVVMVGGSTRVPKVRSSVGQLFGREPLTDIDPDEVVAIGAAIQAETLAGNNRDGEELLLLDVIPLSLGLETMGGLMEKIIPRNTTIPVARAQDFTTYKDGQSAMMIHVLQGERELISDCRSLARFELRGIPPMVAGAAKIRVTFQVDADGLLSVSARELASGVEASIQVKPSYGLTDGEIARMLEDSFRKADQDRDARALREQLVDAQRLLEAVEAALIADGERLLSAEERAAIEAQMAELRALLDSQDVSAIERQIKRLSQITDAFAARRLDSTVKAALAGRRLNDIED
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PETG_SKECO
Sequence: MVEPLLSGIVLGMITVSAFGLFVAAFLQYRRGNQFEI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MVP_DIPOM
Sequence: MEDSIIRIAPYHYIHVLDQNTNVARIENGPKTYIRQDNERVLFPPERMVTIPPRHYCVVANPVVRDREGMPVCDGFGQARLRHGDREVRLSQDPFPLYPGEELGQVATALQVVKTNSALHLQAQLDFEDHGEKRVAGDEWLFEGPGTYIPRTEVVMICWINAIVIRHNQGLRLRARKDTRDRDGRDRVTGEEWMVRRVGAYLPGVYEEVLDVVNAFILTEKRALHLRALQTVKDMRDRVRRTGEEWLVTLAEAEAYVPGVEEEVVGQVEVTTLGTRQYCVVLDPVGADGKPQLGQKLVVKGEKSFFLQPGEHLEAGIQDTYVLSEEEGLVLRAVEAFEEKDEAGKVHCRKPGDRWMIRGPVEYVPPVTVEVLSYRHAIPLDQNEGIYVRDLKSGKVRAVIGESYMLSQDEELWEKTLPPNVEALLTPDKDPVLNRNVHQSEAGHQEEGVKKRDPTRVVTFRVPHNAAVQVYDYSQKSARVVFGPELVMLETDEQLTVLSLSGGRPKRPGVIRSLCLLLGPDFFTDVIVIETADHARLQLQLAYNWHFEVKDRSDPMESAKVFSVLDFVGDACKAIASRIRGAVASVQFDDFHKNSSRILRAAVFGLDPELRVRERLLFPQNSLCVTSVDVHSVEPVDQRTRDALQRSVQLAIEITTKSQEAAARQEAARLEQEAKGRLERQRILDQAESERARRELLLLEADSTAVESRGAARAEAESRAEASRIEGEGSVLQAKLKAQALDIETEAELERLTKARERELKYIAEQNRLEVEKTRQLSELESRRFQEMVQAIGADTIRAIAESGPELQVKLLQGLGLNSTLITDGSTPVNLFSAAKGMLGVPAMSMEHRGSE
What is the function of this protein?
Required for normal vault structure.  Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction.  Vaults may also play a role in nucleo-cytoplasmic transport (By similarity).
What are the official names of this protein?
Major vault protein, MVP100, P100.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HELI_EHV2
Sequence: MEEPGAGFILNMTSDSKVRAIVGRIRGLAAKTVPPPEMSWFDSQFDPEDAEGPFLPFSTFLITGTAGAGKSTSISALYQSLNCLITGATAVAAQNLSNGLKTYCPTIYSAFGFKSRHINILPRHGRNAPARDMEGIQRNELCKYWPVISDILGEFTKKKQRGQYEHLTGAAFGALAKMGTPTLWTTNIIVIDEAGTLSSHILTAVVFLYWFYNSWLQTPLYKSGAVPCVVCVGSPTQTDAIQSTYNHSMQKHHIQECDNILTFLMKHEAVSRYVDLNHNWALFINNKRCTDPEFGHLLKTLEYNLDISPRMVDYIDRFVVPKSKILSPLEYVGWTRLFVSHREVKAYLTALHETLSLNQGGATAEADARLFTCPVVCEVFTDTFNEYREAVNLPGLTVTEWLQKNLCRLSNYSQFIDQDLSAVHIETGEESTKVTYLVKYVKNSYVSLNGKTKKCICGFMGTFEKFKTILDNETFIDAHSHDQPEYVYSFLNTLLYNGMYAFHKHGLDAGDEGYLDALRRLPIPPNITHLSTFQDALDQTEAALLNPESDIFYHMTCAPPSASSASLSTLISFYMSLKSVFLQRLALAVSRFGRDFAERTFQTFTINMMIQNGVDFTSASERLFGLLGYASNVDTYKLKGYTFIPVGFGRFNQAELSRDLRDKMPVVVVEDPHGFIACLENNVNKMTEVMENGDLIHICTAGDYGISSKLAMTIAKAQGMSLSRVAVCFGNSKFVRKSHVYVAISRATDPRHMVIDCNPLKNLEEDREDNKTSKYIVQALNNPDTILVY
What is the function of this protein?
Component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase synthesizes short RNA primers on the lagging strand that the polymerase elongates using dNTPs.  Possesses helicase-like motifs and therefore may act as the helicase subunit of the complex.
What are the official names of this protein?
DNA replication helicase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae helicase family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: H2B3_ORYSJ
Sequence: MAPKAEKKPAAKKPAEEEPAAEKAEKAPAGKKPKAEKRLPAGKAEKGSGEGRKAGRKKAKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAGESAKLARYNKKPTITSREIQTSVRLVLPGELAKHAVSEGTKAVTKFTSA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.3.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GLT11_HUMAN
Sequence: MGSVTVRYFCYGCLFTSATWTVLLFVYFNFSEVTQPLKNVPVKGSGPHGPSPKKFYPRFTRGPSRVLEPQFKANKIDDVIDSRVEDPEEGHLKFSSELGMIFNERDQELRDLGYQKHAFNMLISDRLGYHRDVPDTRNAACKEKFYPPDLPAASVVICFYNEAFSALLRTVHSVIDRTPAHLLHEIILVDDDSDFDDLKGELDEYVQKYLPGKIKVIRNTKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAAIREDRHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPLSELGRAEGATAPIKSPTMAGGLFAMNRQYFHELGQYDSGMDIWGGENLEISFRIWMCGGKLFIIPCSRVGHIFRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSYGNISERVELRKKLGCKSFKWYLDNVYPEMQISGSHAKPQQPIFVNRGPKRPKVLQRGRLYHLQTNKCLVAQGRPSQKGGLVVLKACDYSDPNQIWIYNEEHELVLNSLLCLDMSETRSSDPPRLMKCHGSGGSQQWTFGKNNRLYQVSVGQCLRAVDPLGQKGSVAMAICDGSSSQQWHLEG
What is the function of this protein?
Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1.  O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).  Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.  Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1.  Not involved in glycosylation of erythropoietin (EPO).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 11, Polypeptide GalNAc transferase 11, GalNAc-T11, pp-GaNTase 11, Protein-UDP acetylgalactosaminyltransferase 11, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: Y3162_BORA1
Sequence: MRRLLDFLRRGLIRPDPRHAQGKRAEAQGLRLLRAQGLRLLARNARNRHGELDLIMLDGEVLVVVEVRWRSGSAFGGAAASIGPAKQARLARAAACWLAGSEHAGRRLRFDVLAFEAGQARWLRGAFEPPAYIASQALRARGRRR
What are the official names of this protein?
UPF0102 protein BAV3162.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: SYFA_METCA
Sequence: MNSSPESTLEQASRLLAAAGSVAELDQVRVRYLGKKGEFTEQMKTLGTLSPEERKEFGQRVNQARDEFQRLLERRKAALEAEALARRLSSETIDVTLPGRGQRLGGLHPVTLTLRRITRLFRSVGFSVVEGPEIEDDFHNFEALNIPAHHPARAMHDTFYFSEHLLLRTHTSPVQIRVMESGQPPLRVIAPGRVYRCDSDLTHTPMFHQVEGFWVDEQVSFADLKGTLYEFLTGFFEKDCAVRFRPSYFPFTEPSAEVDIECVICDGRGCRVCKHSGWLEVMGCGMIHPRVFEAVGIDPERYSGFAFGLGVERLTMLRYGINDLRLFFENDLRFLRQFKPF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDD_POLNA
Sequence: MKIVVTGAAGFIGSNLVKGLNARGIDDIIAVDDLTQGDKFRNLADLRIADYMDAGDFYDRFAEGAFGHVEAVFHEGACSDTMEPDGKYMMANNYTLSCNLFRACQNQNTRLLYASSAATYGGSDTFSESPEFEKPLNVYGYSKLLFDQHMRRELGMRFENAQTQVAGFRYFNVYGPREQHKGRMASVAFHQFNQFQADGKVKLFGDYGGYGPGGQMRDFVFIDDVVAVNLWFFDHPEKSGIFNLGTGRAQPFNDVAIAVVNTLRQSQNAAPLSLEDAVRGGMIDYVGFPEALVGKYQSYTQADLGALRAAGCQHVFADVQSGVTAYMQWLSNAKN
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: RL14_CENSY
Sequence: MSQGRSRGKAKGVEEFRPYVTRALPVGARVTCADNSGAKVLEIIMVQKAKTRVSRLPAAAVGDYVNVVVKKGPAELRKQVHGAVIIRQKYPVRRLNGVRVAFEDNAAVLTTPEGEMKGTDIKGPVAAEASEKWPRLANLASMVV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ASNA_DROYA
Sequence: MVDNLEPLEPSLQNLVEQDSLKWIFVGGKGGVGKTTCSSSLAVQLSKVRESVLIISTDPAHNISDAFDQKFTKVPTKVNGFDNLFAMEIDPNAGLNELPEEYFEGENEALRVSKGVMQEMINALPGIDEAMSYAEVMKLVKGMNFSVVVFDTAPTGHTLRLIAFPQVVEKGLGKLLRLKMKVAPLLSQFVSMLGMADLNADTLSQKLDDMLRVITQVNEQFKNPDQTTFVCVCIAEFFSLYETERLVQELTKCGIDVHNIIVNQLLFLQNSHDSCSMCASRFKIQEKYLDQIADLYEDFHVTKLPLLEKEVRGPESIRSFSENLMKPYEPKAKPKE
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase ASNA1 homolog, Arsenical pump-driving ATPase homolog, Arsenite-stimulated ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: RBM18_BOVIN
Sequence: MEAETKTLPLENASILSEGSLQEGHRLWIGNLDPKITEYHLLRLLQKFGTVKQFDFLFHKSGALEGQPRGYCFVNFETKQEAEQAIQCLNGKLALSKKLVVRWAHAQVKRYDHNKNDKILPISLEPSSSTEPAQSNLSVTAKIKAIEAKLKMMAENPDAEYPAAPVYSYFKPPDKKRTTPYSRTAWKSRR
What are the official names of this protein?
Probable RNA-binding protein 18, RNA-binding motif protein 18.
Protein: RP18_VAR67
Sequence: MSSFVTNGYLPVTLEPHELTLDIKTNIRNAVYKTYLHKEISGKMAKKIEICKDVELPLGEIVNNSVVINVPCVITYAYYHVGDIVRGTLNIEDESNVTIQCGDLICKLSRDSGTVSFSDSKYCFFRNGNAYDNGSEVSAVLMEAQQGTESSFVFLANIVDS
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG133, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 18 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 18 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: Y749_TREPA
Sequence: MQDKALFSGALDTPFMQVITWARLYHKNQKRYEKIKKSFTFHETCLQSTKGIVAERILKPCVRRKVNGKFRST
What are the official names of this protein?
Uncharacterized protein TP_0749.
Protein: RPOC_BACCR
Sequence: MIDVNNFEYMKIGLASPDKIRSWSYGEVKKPETINYRTLKPEKDGLFCERIFGPQKDWECHCGKYKRVRYKGVVCDRCGVEVTRAKVRRERMGHIELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEVIYFASYVVTESGDTPLDKKQLLSEKEYRAYRDRYGSTFQAAMGAEAIKKLLQDIDLDKEVDFLKEELKTAQGQRRTRAIKRLEVLEAFRNSGNEPSWMILDVLPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPSIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKMYQCGLPKEMALELFKPFVMKELVEKGLAHNIKSAKRKIERVQPEVWDVLESVIKEHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVCTAYNADFDGDQMAVHVPLSSEAQAEARLLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLEREGAIGEGMVFKDANEALLAYQNGYVHLHTRVAVAASAVNNATFTEEQKSMLLLTTVGKLIFNEILPESFPYINEPTNSNLEKETPAKYFVEKGANIKEIIASREEVAPFSKKILGNIIAEVFKRFQITETSRMLDRMKNLGFKYSTKAGITVGVSDILVLGEKDEILHEAQAKVDNVIKQFRRGLITEEERYDRVISIWSNAKDVIQGKLMKSLNKRNPIFMMSDSGARGNASNFTQLAGMRGLMANPSGRIIELPIKSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIVREDDCGTDRGLLIGAIKEGNEVIESLYDRLVGRFARKTVKHPETGEVLVAENQLITEDIAHIVENSGVETVNIRSAFTCNTRHGVCKKCYGRNLATGTDVEVGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRIQEIFEARNPKGQAVISEIDGVIAAINDVKDRQEVVVQGEVEARTYAIPYGARLKVTPGQPISHGKELTEGSIDPKELLKVTDITAVQEYLLREVQKVYRMQGVEIGDKHVEVMVRQMLRKVRVSDAGETDVLPGTLLDIHQFTDANAKVLLQGKQPATARPVLLGITKASLETDSFLSAASFQETTRVLTDAAIKGKRDELLGLKENVIIGKLVPAGTGMNRYRKVDLVKTTQDDMNVENDEVYVEQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PCKG_NOCFA
Sequence: MTSATIPGLRGSDGQAPTEHSELLAWVQEVAELTQPERVVWADGSDEEWERLTDQLVEAGTFKRLDPKKKPNSFLALSDPSDVARVESRTFICSRSEADAGPTNNWVDPAEMRATMTELYRGCMKGRTMYVVPFCMGPLGAEDPKLGVEITDSEYVVVSMRVMTRMGKAALEKMGTDRPFVKALHSVGAPLAEGQQDVPWPCNDTKYITHFPEDREIWSYGSGYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYYIAAAFPSACGKTNLAMIQPTVPGWRAETLGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNHSSNPNAMATMEAGNTVYTNVALTDDNDVWWEGLEGEPDHLIDWKGNDWYLRETETLAAHPNSRYCTPMSQCPILAPEWDDPQGVPISAILFGGRRKTTVPLVTESFDWQHGVFMGATLSSEQTAAAEGKVGTVRRDPMAMLPFLGYHVGDYLDHWIQLGKSADATKLPKIFYVNWFRRGEDGRFLWPGFGENSRVLEWIVGRIEGSADAEETAIGNVPRAAHLDLDGLDVDPADVDEALAVKAEEWRKEIPLIEEWFEFVGDKLPSGVRDEFEALKQRLG
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC6A1_MOUSE
Sequence: MATDNSKVADGQISTEVSEAPVASDKPKTLVVKVQKKAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSLVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPSEDIVRPENGPEQPQAGSSASKEAYI
What is the function of this protein?
Mediates transport of gamma-aminobutyric acid (GABA) together with sodium and chloride and is responsible for the reuptake of GABA from the synapse (PubMed:15234345, PubMed:16150932, PubMed:8420981, PubMed:30270321).  The translocation of GABA, however, may also occur in the reverse direction leading to the release of GABA (By similarity).  The direction and magnitude of GABA transport is a consequence of the prevailing thermodynamic conditions, determined by membrane potential and the intracellular and extracellular concentrations of Na(+), Cl(-) and GABA (By similarity).  Can also mediate sodium- and chloride-dependent transport of hypotaurine but to a much lower extent as compared to GABA (PubMed:30270321).
What are the official names of this protein?
Sodium- and chloride-dependent GABA transporter 1, GAT-1, Solute carrier family 6 member 1.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Presynapse. Note=Localized at the presynaptic terminals of interneurons.
Protein: CYB_PTEQU
Sequence: MTNIRKTHPLLKIINDSLVDLPVPSSVSSWWNFGSLLAACLAVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWILRYLHANGASMFFICLYIHVGRGLYYGSYMYSETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIIAALVVVHLLFLHETGSSNPTGIPSDPDMVPFHPYHTIKDILGILTMLTVLSMLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIIPMLHTSKQRTMMFRPLSQCLFWLLAADLLTLTWIGGQPVEHPYIIIGQAASVLYFTIILLLMPLVSTMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYH_RHOOB
Sequence: MSKASTFSAPKGVPDYVPPQSSEFVAVRDGLTRAARLAGYGHIELPIFEDTGLFARGVGESTDVVSKEMYTFADRGDRSVTLRPEGTAGVMRAVIEHGLDRGQLPVKLSYAGPFFRYERPQAGRYRQLQQVGVEAIGVDDPALDAEVIAVADAGFRGLGLEGFRLEITSLGDDTCRPQYRERLQEFLFALPLDEETRRRAEINPLRVLDDKRKEVREMTADAPLMLDHLSDTAKAHFDEVLAHLDALGVPYVVNPRMVRGLDYYTKTTFEFVHDGLGAQSGIGGGGRYDGLMAQLGGQPLSGIGFGLGVDRTVLALAAEGKTAGSTARCEVFGVPLGEEAKAKLVVIAQQLRAQGIRVDLAYGNRGVKGAMKAADRSGAALALVLGDRDIAEGTVGIKNLATGDQESVSSADVLARVGAILGA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_YERPA
Sequence: MTTNYAHYIDHTLLAMDATEAQIIKLCEEAKQHHFYAVCVNSGYVPVAAQQLAGSSVKVCSVIGFPLGAGLTAAKAFEAQAAINAGAQEIDMVINVGWLKSGKIADVKADIKAVRDNCAATPLKVILETCLLSDEQIVQVCEMCRELDVAFVKTSTGFSTGGAKEEHVKLMRATVGPVMGVKASGAVRDRATAETMIQAGATRIGTSSGVAIVSGQQAAASGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMB_HAEDU
Sequence: MKHKKTSSRAIAAQIMLQVLDHGKSLSTLIPAAQQQLDAKDIPLVQEITFGICRVLPRLEAIIQQLVTKPLKGKSRLVHCLLLVGLYQLLYMRIPVHAAVDEVVNATKLVKLDSFRALTNGVLRRFLREQQTILAKVDKHWQTLHPEWLVNMLKQVYPNWREIMDANNQRPPMWIRVNTQHCTPQDYSALLGDLAVKTTNSSACLPSSAIQLVNPLSVDKLPYFSRGWATVQDCHAQWSATLLAAKNGEMILDACAAPGGKTTHILEQAPQAKVIALDIEESRLVRVRENLARLGLTADVRCGDATTPTKWLADDVMFDRILLDAPCSATGVIRRHPDIKWLRQAGDISELVELQAKILSALWHRLKPNGTLVYATCSILPAENSEQIIQFITANPDAELIEMDFNGEKAIMKQFLPQQNGGDGFFYAKLRKLDK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.