PharMolix/UniProtQA huggingface dataset:
Protein: CLCA_VIBPA
Sequence: MTKRERIVKSVLAHVPKDAINQFVSRGSTPFSVLIMAAIVGTLAGFVGTYFELAVHFVSETRTEWLRSEIGSVLPLWLAAVLISALLAFIGYFLVHRFAPEAAGSGIPEIEGAMDNIRPVRWWRVLPVKFFGGMGALGSGMVLGREGPTVQMGGAVGRMVTDIFRVKDDDTRHSLLASGAAGGLAAAFNAPLAGIMFVVEEMRPQFRYSLISIRAVIISAIMANIVFRAINGQDAVITMPQYQSPALQTLWLFLLLGALFGVFGVIFNKLITVAQDSFVAIHKNDRKRYLITGSILGGVFGLLLLYVPQLTGGGIALIPDVTTGNYSISILVLLFIGRVVTTLLCFGSGAPGGIFAPMLALGTLFGYAFGASADVLLPTLDIEPGVFAIAGMGALFAATVRAPITGILLVIEMTNNYYLILPLIITCLGAVIVAQLLGGQPIYSQLLHRTLKNDKLRQQDLPENQAS
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DRL45_ARATH
Sequence: MAGELISFGIQNLWNLLSQECELFQGVEDQVTELKRDLNLLSSFLKDADAKKHTSAVVKNCVEEIKEIIYDGEDTIETFVLEQNLGKTSGIKKSIRRLACIIPDRRRYALGIGGLSNRISKVIRDMQSFGVQQAIVDGGYKQPQGDKQREMRPRFSKDDDSDFVGLEANVKKLVGYLVDEANVQVVSITGMGGLGKTTLAKQVFNHEDVKHQFDGLSWVCVSQDFTRMNVWQKILRDLKPKEEEKKIMEMTQDTLQGELIRLLETSKSLIVLDDIWEKEDWELIKPIFPPTKGWKVLLTSRNESVAMRRNTSYINFKPECLTTEDSWTLFQRIALPMKDAAEFKIDEEKEELGKLMIKHCGGLPLAIRVLGGMLAEKYTSHDWRRLSENIGSHLVGGRTNFNDDNNNTCNYVLSLSFEELPSYLKHCFLYLAHFPDDYEINVKNLSYYWAAEGIFQPRHYDGEIIRDVGDVYIEELVRRNMVISERDVKTSRFETCHLHDMMREVCLLKAKEENFLQITSSRTSTGNSLSIVTSRRLVYQYPITLDVEKDINDPKLRSLVVVANTYMFWGGWSWMLLGSSFIRLELLRVLDIHRAKLKGGKLASSIGQLIHLRYLNLKHAEVTHIPYSLGNLKLLIYLNLVILVSGSTLVPNVLKEMQQLRYLALPKDMGRKTKLELSNLVKLETLKNFSTKNCSLEDLRGMVRLRTLTIELRKETSLETLAASIGGLKYLESLTITDLGSEMRTKEAGIVFDFVYLKTLTLKLYMPRLSKEQHFPSHLTTLYLQHCRLEEDPMPILEKLHQLKELELRRKSFSGKEMVCSSGGFPQLQKLSIKGLEEWEDWKVEESSMPVLHTLDIRDCRKLKQLPDEHLPSHLTSISLFFCCLEEDPMPTLERLVHLKELQLLFRSFSGRIMVCAGSGFPQLHKLKLSELDGLEEWIVEDGSMPQLHTLEIRRCPKLKKLPNGFPQLQNLELNELEEWEEWIVEDGSMPLLHTLRIWNCPKLKQLPDGLRFIYSLKNLTVPKRWKKRLSKGGEDYYKVQHIPSVEFY
What is the function of this protein?
Potential disease resistance protein.
What are the official names of this protein?
Probable disease resistance protein RDL6.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: CR032_ESOLU
Sequence: MVCIPCIVIPVLLWVYKRFLEPIIYPFIGPIISRFWPTNIAVQENGTGDVKASEKSNGACKTKADVVVANGPSANGPATPISDKKID
What are the official names of this protein?
UPF0729 protein C18orf32 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0729 family.
Protein: NNRD_FLAPJ
Sequence: MRDFCQIDTQEIIKRYKPIDKYTHKGLQGHALIIGGSYGKMGSVVLASKACIRSGAGLVTAYIPKCGCDIVQISVPEVMVITDDYLEHIALINFDLNLKSIGIGVGMGQHPDTQHAFFNFLKSNKLPLVIDADALNILSQNIEWLSLLPKKAILTPHQKELERLIGKWSSEEEKLEKVKRLCLEYDLIFVLKGAPTMIVNNKSTYENTTGNQALATAGSGDVLAGIITSLLAQSYEPINAAIIGVYLHGLTADIAYPKVGYQSFIASDIIETLGEAYLHIIK
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ADP-dependent (S)-NAD(P)H-hydrate dehydratase, ADP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
Protein: KCNC1_MOUSE
Sequence: MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGRKPLRGMSI
What is the function of this protein?
Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons.  The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient (PubMed:2599109, PubMed:1400413).  Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well.  Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons.
What are the official names of this protein?
Potassium voltage-gated channel subfamily C member 1, NGK2, Voltage-gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.1/KCNC1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Presynaptic cell membrane. Note=Localizes in parallel fiber membranes, distributed on the perisynaptic and extrasynaptic membranes away from the active zones.
Protein: YH069_YEAST
Sequence: MDSCSSTPFVTGVLLPSAVFSFLFCTLVSSSFGLDEFNLTTCGIRGTLKMQFLKFLENTLIFLGSGNLTAHIGILVMKNDLSNSRIWRFTGGLYGNTPDILHELINLLNFWNTGSAIFMQ
What are the official names of this protein?
Putative uncharacterized membrane protein YHR069C-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CB27A_HUMAN
Sequence: MTVKWKQLSAPASGAEIQRFPVPAVEPVPAPGADSPPGTALELEEAPEPSCRCPGTAQDQPSEELPDFMAPPVEPPASALELKVWLELEVAERGGQHSSSQQLPHCSQSWAQWKLWRQRPGFAIWAPLPHWRGTSLIQQSSSPAAEGPAATAAGAVCLPAGGAGEQEKEPVSRGSSRSSCSQRRPPPPGMEVCPQLGIWAICP
What are the official names of this protein?
Uncharacterized protein C2orf27A.
Protein: MOCS3_PIG
Sequence: MAAREEVLALQAEVARREEELSSLKHRLAAALLAEQESERLLPVSPLPPKAALSQDEILRYSRQLVLPELGVQGQLRLATASVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEVSNLARQVLHGEALAGQAKVFSAAASLRRLNSAVECVPYAQALTPATALDLVRRYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFEGQITVYHYGGGPCYRCVFPQPPPAETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGLGPSYSGSLLLFDALRGLFRRIQLRRRRPDCAACGERPTVTELQDYEGFCGSSATDKCRSLQLLSPEERVSVIDYKRLLDSGSPHLLLDVRPQVEVDICRLPHALHIPLKHLERRDAESLKLLGEAIREGKQGTQEGASLPIYVICKLGNDSQKAVKILQSLPDLDSLLVQDVVGGLMAWAAKVDGTFPQY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A.  Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase MOCS3, Molybdenum cofactor synthesis protein 3.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODN_RHILV
Sequence: MHELSLADVPSRIGQELGKSEWITVDQTTIDLFADATHDHQFIHVHPERAAVESPFGGTIAHGFLTLSLLSAMNFSGMPKIREQTMGLNYGLDRVRFMSPVKTGSRVRGRFVLSECQFRGASMLVTTYEVTVEIENENRPALTANWITIIQFDPNDRPKGI
What is the function of this protein?
Involved in the production of the root hair deformation (HAD) factor specifically on medicago.
What are the official names of this protein?
Nodulation protein N.
What is the protein family that this protein belongs to?
To the R.meliloti counterpart.
Protein: ENOF1_BOVIN
Sequence: MVHGRVSRLSVHDVRFPTSLGGHGSDAMHTDPDYSAAYVVLETDAEDGLKGYGITFTLGRGTEVVVCAVNALAPHVLNKDLGEIVGDFRGFYRQLTSDGQLRWIGPEKGVVHLATAAVLNAVWDLWAKQEGKPLWKLLVDMDPRTLVSCIDFRYITDVLTEEEACEILRQSQVGKKEREEQMLAHGYPAYTTSCAWLGYPDATLKQLCSEALKDGWTRFKVKVGADLQDDIRRCRLVRNMIGPEKTLMMDANQRWDVPEAVEWMTKLAEFKPLWIEEPTSPDDILGHAAISKALAPLGIGVATGEQCHNRVIFKQLLQAKALKFLQIDSCRLGSVNENLSVLLMAKKFEIPVCPHAGGVGLCELVQHLIIFDFISVSASLQDRMCEYVDHLHEHFKYPVLIREAAYMPPKDAGYSTEMKEDSVKRHRYPDGEVWKKLLSAQGN
What is the function of this protein?
Plays a role in the catabolism of L-fucose, a sugar that is part of the carbohydrates that are attached to cellular glycoproteins.  Catalyzes the dehydration of L-fuconate to 2-keto-3-deoxy-L-fuconate by the abstraction of the 2-proton to generate an enediolate intermediate that is stabilized by the magnesium ion.  May down-regulate thymidylate synthase activity, possibly already at the RNA level, by promoting the degradation of TYMS mRNA via an antisense RNA-based mechanism.
What are the official names of this protein?
Mitochondrial enolase superfamily member 1, L-fuconate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. ENOSF1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SECG_TRICV
Sequence: MLFLKLIWLLVSIFLISIIYLRVPRNQGLTSFATKSDLLGSPNSTEKFLNNFTLILIISYYLIAVKLNQMSIIG
What is the function of this protein?
Involved in protein export.  Participates in an early event of protein translocation across the chloroplast thylakoid membrane (Potential).
What are the official names of this protein?
Probable protein-export membrane protein secG.
What is the protein family that this protein belongs to?
Belongs to the SecG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CHS2_PARBR
Sequence: MAQESSNMDQSKSDNVTDNKPNRSLISMARPSPQRCHPLDQQSASTSSLPTSRPSSSPGQSPNITPSILTSDTLHLPARSVSPTRPWTPSRGSEWSRHMPLSVSSVNYEPPEINCSPRPGTPSSKYGGSPRRPLRQPVVCWPPASSAGETSIDIADGGDDSEDPFVVGERTVHQRSNTRSSIKLIQFTMQLSPQLLQMKRTPWVKLTLDDGEDDESDFNVHYGPAPTGRQERRGVRKAQMTKKEVRLMNGELVLECKIPRMLHSFLPRRDDREFTHMRYTAVTCDPDDFTVKGFKLRQNIGSTMRETELFVCVTMYNENEIDFTRTMHGIMRNISHFCSRTKSRTWGKDGWQKIVVCIIADGRQKVHPRTLNALAAMGVYQDGIAKNVVNQKPVNAHVYEYTTQVSLDPDLKFKGAEKGIMPCQVIFCMKERNEKKLNSHRWFFNAFGRALNPNICILLDVGTKPEPTALYHLWKAFDQDSNVAGAAGEIKAGKGKGCLGLFNPLVASQNFEYKMSNILDKPLESVFGYITVLPGALSAYRYHALQNDSTGHGPLSMYFKGEMLHGKNADVFTANMYLAEDRILCWELVAKREEQWVLKFVKSAVGETDVPDTVPEFISQRRRWLNGAFFAAVYSLIHFRQIWRTDHTITRKILLHIEFLYQFVSLAFTFFSLANFYLTFYFIAGALSDPTVDPFGHNIGKYIFAILRYTCVLLICLQFVLSMGNRPQGAKKMFLSGMIIYCIIMMYTVFSALYMVVMQLKTSKEMIKDSLSLGNNTFTYIIVSTLSTVGLYFFMSFLYLDPWHMFTSSIQYFALLPSYICRLQIYAFCNTHDVTWGTKGDNVIRTDLGTARITSSSTVELEMPSEQLDIDSGYDESSAISATDSKCPRQSHPRRRCRKTTTAVRTYMVSVWFIANAILAMAVSEAFTEKSVGNNAYLAFVLWSVASLAVFRAVGSTAFAILNVVHRVMEGKMKFAAAGGTGYGYGSYVGSSSGGGGGSSGVRSSGAGSSLGLSSGMGEKVSDWASETGWAVKRTAGKLRFWR
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 2, Chitin-UDP acetyl-glucosaminyl transferase 2, Class-II chitin synthase 2.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class II subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LDH2_LACAC
Sequence: MSRKVFLVGDGAVGSTFANDLLQNTTVDELAIFDVAKDRPVGDSMDLEDITPFTGQTNIHPAEYSDAKDADVCVITAGVPRKPGETRLDLVNKNVKILKTIVDPVVESGFKGVFVVSANPVDILTTLTQKISGFPKDRVIGTGTSLDSMRLRVELAKKLNVPVAKVNSMVLGEHGDTSFENFDESTVDNKPLRDYSEINDNVLSEIESDVRKKGGKIITNKGATFYGVAMMLTQIVSAILDNRSICLPLSAPINGEYGIKHDLYLGTPTIINGNGIEKVIETKLSDVEKAKMINSADKMQEVLSGVEM
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 2, L-LDH 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBG4_MOUSE
Sequence: MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAASDLLAYCEAHVREDPLIIPVPASENPFREKKFFCTIL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: XKZA_BACSU
Sequence: MISTIYRERTAADLKSRIDHVLLNGQKTEIVELAIDGATVTVLTKREEDIKHIETVQIFDELGNVITERKTDLDVSENRTLDFRFTFEVV
What are the official names of this protein?
Uncharacterized protein XkzA.
Protein: LEUC_PROMH
Sequence: MGKTLYQKIYDAHVVREVANETPIIYIDRHLVHEVTSPQAFDGLRTKGRAVRQPNKTFATMDHNVSTQTKDINACGDMARIQMQELMKNCQEFGVTLYDLNHPYQGIVHVMGPEQGLTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQSRAKTLKIEVQGKTANGITAKDIVLAIIGKLGSAGGTGYIIEFTGEAIEALSMEGRMTLCNMAIEMGAKAGLVAPDETTFAYLKGRQFAPQAPLWDEAVAYWKTLKSDEDAIFDATVTINAAEIAPQVTWGTNPGQVIAIDQIVPRLNSFNDPVERASAEKALAYMGLTEGVNLTDITIDKVFIGSCTNSRIEDLRAAAKIAKGHKVASHVQAIVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAIHGHFADIRTFATVS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: GLPK_VIBC3
Sequence: MTEQKYVVALDQGTTSSRAVVLDHDANIVSVSQREFTQIYPQAGWVEHDPMEIYATQSSTLVEALGKAGIRSDEVAAIGITNQRETTVVWNKETGKPVYNAIVWQCRRTATICEELKARGLESYIRDNTGLVLDPYFSGTKIKWILDNVEGAREQAEAGQLLFGTVDTWLVWKMTQGRVHVTDYTNASRTMLFNINTLQWDEKILAEFNIPLSMMPEVKKSSEVYGQTNIGGKGGTRIPIAGIAGDQQAALYGQMCVQAGQAKNTYGTGCFLLMNTGQEKVTSHNGLLTTLACGPRGEPAYALEGAVFMGGASIQWLRDELKLISDARDSEYFATKVDTSNGVYVVPAFTGLGAPYWDAYARGTIVGLTRGVNSNHIIRATLESIAYQTRDVLDAMQADSGIKLSALRVDGGAVANNFLMQFQADVLDTEVHRPKVTEVTALGAAYLAGLAVGFWDGLEELQGKAEIDRSFKPHHDEEKRQRRYKGWKRAVKCAQAWAVLHNEEE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: DPH2_XENLA
Sequence: MAAALFSSNGEEAIGRNIDIGQVDIQSSPEKDLGEFYEIEKTVEFIQRNAAQKVALQFPDDLLLDSVKVARKLEEATGAKTYILGDTSYGSCCVDEVAAEHVKANVLVHYGRACLSPCCRLPVSYVFGRKAVNMDLCAEAFLSHYRDTESHVVVLSDVVYDHALGELAKRIRSAYPNVIFSKLTSCGETASPDEIVKFGRRFSPDLRLWPESYGIFYVGGEGSTLNNLMLTWPRCSFFSFNPFTGEGRTEGLHVNRALMIRFYLIERARDAHVFGILVGTLGVSDYLSALKHLKNIIHLAGKKSYMFSVGKLNPAKLANFPEIDVFVLVACPENSLLDSSEFYKPVVTPDEMEIACNPAREWHGYCITNFRELLPGGSAYVEFPETDPSDAHHTDVSLITGNLRSSHLTVAETLEKDSDTSLVQRNSKTALAQMSSAASYLASRSWQGLDKALGQTPVVKAVEGRKGIAIAYEDEICS
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (By similarity).  Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the dph1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
Protein: SYE2_PETMO
Sequence: MISNTVRTRFAPSPTGYLHVGGARTALFNYLFSKKNEGKFILRIEDTDIERSTKESEDQLINTLKWLNLNWDEGPIIGGDYEPYRQSERLEIYQRRAKELIEKGKAYEAYISPEEIEEVKNQLISEGKPPHYTYDLISKYNTKERIEEYNYKGLKPVIFLKMPQKDYELDDKIKGKVIFKKGSIGDFIILRSNGIPTYNFAVVVDDIEMKITHVIRGDDHLPNTLRQMAIYEAFEVEPPIFAHVSMILGPDGKKLSKRHGATSVEEFMVQGYLPEAVDNYLALLGWSHPEGKEILPLSEIIDNFTLDRVNSSPAIFDEKKLKWMNGQYLRNKPLEEIYQLAEPFVTGSKLLSKEQYEVNKKWVIKALETILSSVEILSEIPEKMEVFLKDVYPDTNDPEFKEYFDKRGVKEAINLIYKYFNEDDRWDTQTITENLKNAMNEANPQKKPFYMSLRKILTDSFHGPDLINTIFLLGRNTVLERLQRVIEI
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAS1_PARBF
Sequence: TTNNNNTKAVPEAKAALKQMKLEIANELGISNYDTADKGNMTARQNGYVGGYMTKKLVEMAEQQMSGQQR
What is the function of this protein?
SASP are bound to spore DNA.  They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation.  They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.
What are the official names of this protein?
Small, acid-soluble spore protein alpha, ASSP, SASP.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta-type SASP family.
Protein: RRF_STRMU
Sequence: MANAIVEKAKERFEQSHQSLAREFGSIRAGRANASLLDRIEVEYYGVPTPLNQLASITVPEARVLLVSPFDKSSLKDIEHAINASDIGINPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKVAIRNIRRDAMDEAKKQEKIKEITEDELKSLEKDIQKVTDEAVKHIDSMTANKEKELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_HELPS
Sequence: MAYFLEQTDSEIFELIFEEYKRQNEHLEMIASENYTFASVMEAMGSVLTNKYAEGYPNKRYYGGCEVVDKIESLAIERAKKLFNCQFANVQAHSGSQANNAVYHALLKPYDKILGMDLSCGGHLTHGAKVSLTGKHYQSFSYGVNLDGYIDYEEALKIAQSVKPEIIVCGFSAYPREIDFKKFREIADEVGALLLGDIAHVAGLVVAGEHAHPFPHCHVVSSTTHKTLRGPRGGLILTNDEEIAAKIDKAIFPGTQGGPLMHAIAAKAVGFKENLKPEFKAYAQLVKSNMQVLAKALQEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNAGITVNKNTIPGETRSPFVTSGIRIGSAALSARGMGAKEFEIIGNKISDILNDINNVSLQLHVKEELKAMASQFPVYQQPIF
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_NEIG2
Sequence: MTFQNKKTLVAGLGGTGISMIAYLRKNGAEVAAYDAELKAERVAQIGKMFDGLVFYTGRLKDALDNGFDILALSPGISERQPDIEAFKQNGGRVLGDIELLADIVNRRGDKVIAITGSNGKTTVTSLVGYLCIKCGLDTVIAGNIGTPVLEAELQREGKKADVWVLELSSFQLENTESLRPTAATVMNISEDHLDRYDDLLDYAHTKAKIFRGDGVQVLNADDVFCRAMKRAGREVKRFSLEHEADFWLERGTGCLKQGNEDLISTQDIPLQGLHNAANVMAAVALCEAVGLPREALLEHVKTFQGLPHRVEKIGEKNGVVFIDDSKGTNVGATAAAIAGLQNPLFVILGGMGKGQDFTPLRDALKDKAKGVFLIGVDAPQIRRDLDGCGLNLTDCVTLEEAVQTAYAQAEAGDIVLLSPACASFDMFKGYAHRSEVFIEAFKAL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_CITK8
Sequence: MRVVILGSGVVGVTSAWYLCQAGHDVTVIDREPGPALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTRHYMENKGRMVRLAEYSRDCLKALRASTGIQYEGRQGGTLQLFRTAQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLAQMAEQAGVTFRFNTPVEKLLYEGEQIYGVKCGDDIIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPVAQDDGAPVSTILDETYKIAITRFDKRIRVGGMAEIVGFNTELLQPRRETLEMVVRDLFPRGGHVEQATFWTGLRPMTPDGTPVIGRTRFKNLWLNTGHGTLGWTMACGSGQLLSDILSGRTPAIPYDDLSVARYSPGFTPSRPRHLHGAHN
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: TOC34_CHLRE
Sequence: MAQPPRPAEEYDDDVQEDEDELKEGELDDDESHEAASEGGEAAAGDEEAEDDEQDEEDGDEDSQPWAGLNRLPERDDMLDILNELRAEGRKQLTVLLLGKSSVGKSSLINSLLGEAVVRVQAFKLQADTDITTTVVRQVAVGNSEVDGFRLKLIDTCGLEDPEAGDTVNLGALSKIAEDVRGVGIDVVLYCDRLDLYRVDPLDKAIIDAISSTFGRGIWRRTVVALTHANLVQTPPGTDYDSFVNGRVRLIRGAVRGPLFFRPSLPVALVENSETCPVSSESGFRVLPDGEPWLVALVSQLVDMAAARRRPYKYHPRLSSKPSHRFRWLLPVAIAAEVLFYRRFLHPRLDDNQRRVEREEERVWALRGQQRRALGLHRPHRPDKDAAWRLEQMYDDD
What is the function of this protein?
GTPase involved in protein precursor import into chloroplasts.  Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis (By similarity).  Functions as an essential component of the outer chloroplast membrane translocon (TOC) complex, which, in turn, catalyzes the import of nucleus-encoded precursor polypeptides from the cytoplasm to the chloroplast (PubMed:23167510).
What are the official names of this protein?
Translocase of chloroplast 34 homolog, chloroplastic, Cr-TOC34, TOC34p.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. TOC34 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Single-pass membrane protein.
Protein: OBG_STAA2
Sequence: MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.