PharMolix/UniProtQA huggingface dataset:
Protein: HPAB3_PSEYM
Sequence: MVGISGRAGPSGSYNYSGHTDNPEPVSGRARDSNSEANSSNSPQVPPPLNAPASPMPAGRPRFLRSMALSSQTREWLEKGMPTEAEAGVPIRLQERAANTAPQARAEERHTQPADAAAPHARAERGRTLQAPASTSPLYTGAVPRANRIVQQLVEAGADLANIRTMFRNMLRGEEMILSRAEQNVFLQHFPDMLPCGIDRNSELAIALREALRRADSQQAARAPARTPPRSSVRTPERSPAPRTATESSSGSNQRSLLGRFAGLMTSNQRRPSSASNASTSQRPVDRNPPRINLMPTGANRVAMRNRGNNEADAALQALAQNGINMEDLRAALEAYIVWLRPIPLDIANALEGVGITPRFDNPEEAKVDNPLMNLSSALKRRLDA
What is the function of this protein?
Effector protein involved in gene-for-gene resistance in tomato plants.  It is recognized by the host Pto resistance protein and elicits Pto and Prf-dependent hypersensitive response (HR) and programmed cell death (PCD), resulting in host immunity.  In susceptible plants, promotes virulence, in part, by enhancing the development of disease symptoms and bacterial growth.
What are the official names of this protein?
Effector protein hopAB3, Avirulence protein hopPmaL.
What is the protein family that this protein belongs to?
Belongs to the HopAB family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via type III secretion system (TTSS). Localized to the plant cell cytoplasm.
Protein: BIOB_STAAS
Sequence: MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: Y529_SYNP6
Sequence: MAGHSKWANIKRQKARVDAKKAQVFARLSRAMIVAARQGLPDPAANFQLRTAIEKAKAAGIPNDNIERAIAKGAGTLSGDGRQFESVRYEGYGPSGIAILIEALTDNRNRTAANLRAAFSKQGGNLGETGCVSWMFRQRGVVQLTGAIAEADLLKALLDLPAESYDLDESGAIVYCSIADLEALSTQLRQLGYPVEDSELRWIPNDYQLVTDGEQARSLLRLLDTLETLEDVCSVTANLELPPELVTALEATL
What are the official names of this protein?
Probable transcriptional regulatory protein syc0529_d.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGALC_ASPOR
Sequence: MRLLSFIYLVWLALLTGTPQVSATDNGKTSDVAWDKYSLSVKGERLFVFSGEFHYQRLPVPELWLDVFQKLRANGFNTISVYFFWSYHSASEDVFDFTTGAHDIQRLFDYAKQAGLYVIARAGPYCNAETSAGGFALWAANGQMGSERTSDEAYYKKWKPWILEVGKIIAANQITNGGPVILNQHENELQETTYDSNDTKVIYMEQVAKAFEEAGVVVPSSHNEKGMRTVSWSTDYKNVGGAVNVYGLDSYPGSLSCANPNSGFNLLRTYYQWFQNYSYTQPEYLAEFEGGWFQPWGGSFYDSCASELSPEFADVYYKNNIGSRVTLHNIYMTFGGTNWGHSAAPVVYTSYDYGSPLRETREIRDKLKQTKLLGLFTRVSKDLLKTYMEGNGTSYTSDDSIYTWALRNPDSDAGFYVVAHNTSSSREVTTFSLNITTSAGAMTIPDIELDGRQSKIIVTDYSIGSESSLLYSSAEVLTYATLDVDVLVFYLNAGQKGAFVFKDAPADLKYQTYGNSNLSALETSQGTQYSYTQGEGVTAVKFSNGVLVYLLDKETAWNFFAPPTVSSPTVAPNEHILVFGPYLVRGASIKHDTVEIVGDNSNSTSIEIYTGDEHVKKVSWNGNLIDTRATAYGSLIGTVPGAEDIEISLPSLSSWKAQDTLPEISPDYDDSRWTICNKTTSVNSVAPLSLPVLYSGDYGYHTGTKIYRGRFDGQNATGANVTVQNGVAAGWAAWLNGAYVGGFSGDPDKVASWEVLKFNHSSLRSRDNVLTIITDYTGHDQNSQKPIGTQNPRGIMGATLIGGGNFTLWRIQGNAGGEKNIDPVRGPMNEGGLYGERMGWHLPGYQVPESALDSSPLEGVSGAEGRFYTTSFQLDLEEDLDVPIGLQLSAPAGTEAVVQIFMNGYQFGHYLPHIGPQSLFPFPPGVIKNRGQNSLAISMWALTDAGARLEQVELKAYAKYRSGFDFNRDWTYLQPGWKDRTEYA
What is the function of this protein?
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
What are the official names of this protein?
Probable beta-galactosidase C, Lactase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TF3A_ANAAE
Sequence: MGEKLPVVYKRFICSFPDCNATYNKNRKLQAHLCKHTGERPFPCTYEGCEKGFVTLHHLNRHVLSHTGEKPCKCETENCNLAFTTASNMRLHFKRAHSSPAQVYVCYFADCGQQFRKHNQLKIHQYIHTNQQPFKCSHEGCDKCYASPSRLKRHEKTHAGYPCRKDSTCPFVGKTWSDYMKHAAELHSEVTCSICNRTFKRKSFLKEHKKIHREERIVYRCPRENCDRTYTTKFNLKSHILTFHENLRPFVCEHEGCGKTFAMKQSLDRHFNTHDPEKKKMVKPPRPVRSLASRLSGYKPKKSKKKKKPSQTPAMESQEQQPDASKADPLPVLENLTLK
What is the function of this protein?
Involved in ribosomal large subunit biogenesis.  Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III.  Also binds the transcribed 5S RNA's.
What are the official names of this protein?
Transcription factor IIIA, TFIIIA.
What are the subcellular locations of this protein?
Nucleus.
Protein: GRPE_PEDPA
Sequence: MAKEKKEEVKEEEVSEATSTEGSTDVESTNNDDLTTETQATTALDDIKKVEAERDELSDKYIRAQAEIVNMRRRNEKEQASLIKYDGQKLAKAILPALDNLERALAVESASEQLLKGVKMVQTDLLKALKENHVAEIEAEGQAFDPNMHQAVQTVPADDDHPADTVVQVLQKGYILKDRVLRPAMVIVAQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y956_PSEPG
Sequence: MRLIIVSGRSGSGKSTALDVLEDNGFYCIDNLPAGLLPQLAEDALINTELLQPKVAVSIDARNLPSHLTRFPELLEEARARNIQCDVLFLDADEDMLLKRFSETRRRHPLTNANRSLAEAIRVESDLLGPIADLADLKIDTTNLNLYQLRDSIKLRLLNQPEPGTAFLVESFGFKRGMPVDADLVFDVRCLPNPYWKPELREHSGLDQPVIDYLAAQPDVEDMYNDISGYLLKWLPRFAASNRAYVTIAIGCTGGHHRSVYITERLGQHLQQTLKNVQVRHRDL
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein PputGB1_0956.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RT11_MARPO
Sequence: MQKKHGITNMQKKHCITYIQSTFGNTIITLTDYNGNTKTWSSSGSVGFKGSRRSTNYAAQATAENAARVAIQLGFKFVEVRIKGLGYGKESSLRGLKLGGLIITKIRDVTPTPHNGCRPPKKRRV
What are the official names of this protein?
Ribosomal protein S11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYB_KOGBR
Sequence: MTNIRKTHPLMKIVNNAFIDLPTPSNISSWWNFGSLLGLCLITQILTGLFLAMHYTPDTTTAFSSITHICRDVNYGWVIRYLHANGASMFFICLYAHVGRGLYYGSYTFQETWNIGVVLLFTVMATAFVGYVLPWGQMSFWGATVITNLMSAIPYIGTTLVEWVWGGFSVDKATLTRFFAFHFILPFIILALAMVHLLFLHETGSNNPMGIPSDMDKIPFHPYYTIKDILGALLLISALLTLTLFAPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILMLIPMLHTSKQRSMMFRPFSQFLFWTLVADLLTLTWIGGQPVEHPYVTLGQLASILYFLLILVLMPLTSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS9_ECOHS
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RLMH_DINSH
Sequence: MKVTLCVVGRLRAGPERDLINDYLQRFDRTGRGLGLGPASVVEVEDRKGGGKAAEADLLRKAVPRGAVICALDERGKTMSSPQFADSLAGWRDAGRSDLAFLIGGADGLDKALRAQAEARLSFGAMVWPHMLARVMLAEQLYRAAAILAGTPYHRV
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_NITEC
Sequence: MNWSELYWQRITPLHLLLWPVSLLFVLFQSIRRHLYRRAILTSVHLPVPVIVVDSITATSPVKTPLIIQIVNMLRASGLRPGIIGHGYTDNYHSPMSVTIDSPLQLAGKKSLLLAYYLRETCPVWIGHDRIEVAKALLETHKECNVLICNDGLQDLRLQRDFEVVIVDTSVINSGNGLIMPAGPLRDSFARLKHSNVVVQAGHHRQIPDIGEEIRTFYITPLKEHFFNLSRPELTASAAELANKRIHAVTCDPDIQNFLDNLKFLRLTVTPYIFSEDHHFVAEDFPFDEAEIILIPEEDAVKCFNLHDERIWVLQQEYRVDLGLRTIILKKLREKFMDPKLLDILACPLCKGPLIYKKDRLELICKADRLAYPIRDGIPVMLEDEARRLPDEEEIK
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the UPF0434 family.
Protein: NUSB_SYNY3
Sequence: MLARQQPRRVARELSLLSLSQLSRKDTKPETLEQGDLEALLLAATRTLSGEVHEILETASAELSRSHERLLNSEIRASNLNSAKAMLEEAMTLTETVINRLALAVDLPETLQLAGQMEVRKFALELIGTVCRRRQQIDEQLQEAMVDWQLSRLAKIDQDILRLAIAELDYLGVPQKVAINEAVELAKRYSGQDGHRFINGVLRRVTEKKTDGAPVTPGEPR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RS6_NOCFA
Sequence: MRHYEVMVILDPSLDERTVGPSLENMLGVVKTEGGKIDKVDIWGRRRLAYEIRKQAEGIYAVIDLTASPATVNELDRQLGLNESVLRTKVLRHDK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RL34_PARL1
Sequence: MKRTYQPSKLVRKRRHGFRARTQTVGGRKVLAARRSKGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: AIM41_ZYGRC
Sequence: MFRRAAFIKPRLTGFIRFNSTESYNAALGGLKKDLKQAMLAKDELKKTTIRGLLSTIKNKEIDNKDKTLDEFTLFDLYSKLISQRKDSITEFLANKREDLVAKEQHEMGIIEQYRSALPVASKEEIDSKVLQLLKNLKEKEPTLQMKQAFGKIDWKTVNSEWKASPNAVKASIVQQFKNVF
What are the official names of this protein?
Altered inheritance of mitochondria protein 41, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM41 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: COMD1_MOUSE
Sequence: MAGDLEGGKSLSGLLSGLAQNAFHGHSGVTEELLHSQLYPEVPPEEFRPFLAKMRGLLKSIASADMDFNQLEAFLTAQTKKQGGITSEQAAVISKFWKSHKIKIRESLMKQSRWDNGLRGLSWRVDGKSQSRHSTQIHSPVAIIELEFGKNGQESEFLCLEFDEVKVKQILKKLSEVEESINRLMQAA
What is the function of this protein?
Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins.  Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2.  Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation.  Down-regulates NF-kappa-B activity.  Involved in the regulation of membrane expression and ubiquitination of SLC12A2.  Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits and by promoting their ubiquitination presumably involving NEDD4L.  Promotes the localization of SCNN1D to recycling endosomes.  Promotes CFTR cell surface expression through regulation of its ubiquitination.  Down-regulates SOD1 activity by interfering with its homodimerization.  Plays a role in copper ion homeostasis.  Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes.  Can bind one copper ion per monomer.  May function to facilitate biliary copper excretion within hepatocytes.  Binds to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).  Involved in the regulation of HIF1A-mediated transcription; competes with ARNT/Hif-1-beta for binding to HIF1A resulting in decreased DNA binding and impaired transcriptional activation by HIF-1.  Negatively regulates neuroblastoma G1/S phase cell cycle progression and cell proliferation by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a FAM107A- and actin-dependent manner.
What are the official names of this protein?
COMM domain-containing protein 1, Protein Murr1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endosome membrane. Cytoplasmic vesicle. Early endosome. Recycling endosome. Note=Shuttles between nucleus and cytosol. Detected in perinuclear foci that may be aggresomes containing misfolded, ubiquitinated proteins (By similarity).
Protein: HSLV_LISMH
Sequence: MELHATTIFAVQHDGKAAMAGDGQVTLGESVVMKHTAKKVRRLFHDKVIAGFAGSVADAFTLFEKFEAKLNEYNGNLERASVELAQQWRSDSVLRKLEAMLIVMDKDTLLLVSGTGEVIEPDDGILAIGSGGNYALAAGRALKRHNGGQMEAKDIARHALEIASEICVFTNDHITVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_PAEAT
Sequence: MEAKAIARHIRVTPMKARRVVNLVRGKQANEALAILKFAPQAASEPVFKVLQSAMANARVLADRDGVAFDDSDLFITEAFVDEGPTMKRFQPRAQGRAYRIRKRTSHITLVVATPEKEEAR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: THIC_SALA4
Sequence: MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIEARADVETLADRSSAYTRERLTDEGLDALRFTGLLTPKRAKAGHRVTQLHYARQGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMANMSENFRAKGGEIYLKREEV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CAAT4_ARATH
Sequence: MNSLVRRKQVDSVHLIKNDGPHQLAKKLSAVDLVAIGVGTTIGAGVYILVGTVAREHTGPALAVSFFIAGVAAALSACCYAELASRCPSAGSAYHYAYICLGEGIAWLVGWALVLDYTIGGSAIARGITPNLASFFGGLDNLPVFLARQTIPGVGIVVDPCAALLIMIVTILLCFGIKESSTVQAIVTSVNVCTLVFIIVVGGYLACKTGWVGYDLPSGYFPFGLNGILAGSAVVFFSYIGFDTVTSTAEEVKNPQRDLPLGIGIALLICCILYMLLSVVIVGLVPYYSLNPDTPISSAFGDSGMQWAAYILTTGAITALCASLLGSLLAQPRIFMAMARDGLLPAFFSEISPRTQVPVKSTIAIGVLAAALAFFMDVAQLSEMVSVGTLMAFTAVAVCVLVLRYVPPDGVPLSSSSQTLSDTDESRAETENFLVDAIESSDSPLLGNETARDEKYFGKRRKIAAWSIALVCIGVLGLASAASAERLPSFPRFTICGVSAVILLGSLITLGYIDEDEERHNFGHKGGFLCPFVPYLPVLCILINTYLIINIGAGTWIRVLIWLLIGSMIYIFYGRSHSLLNNAVYVPTMTCTRKTTDHLA
What is the function of this protein?
Permease involved in the transport of the cationic amino acids.
What are the official names of this protein?
Cationic amino acid transporter 4, vacuolar.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: YUBL_ECO57
Sequence: MRMSEYFRILQGLPDGPFTRKHAEAVAAQYRNVFIENDHGEQFRLVVRNNGAMVWRTWNFEDGAGYWMNHVIRDFGIIK
What are the official names of this protein?
UPF0401 protein YubL.
What is the protein family that this protein belongs to?
Belongs to the UPF0401 family.
Protein: RL7_ECOSE
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: VATE_METBU
Sequence: MGLETVIKDIMSAAQTEVNVINADADAEVSQILDDARQTAKKIMGDRLAKAEDDIKRLRQQEISSANLEVKRAMLNARKEVLDKVYNNAIDSIVSLPGSKQEELLKAIIDENDSNGSNIYSNKDSEKLVRKLSSLEYAGNIDCIGGLTIENSDGTVRLDYTYDMILKNVNEQSLKQTSDILFG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: NTAN1_PIG
Sequence: MPLLVEGRRVRLPQSAGDLVRAHPPLEERARLLRGQSVQQVGPQGLLYVQQRELAVTSPKDGSVCILGSDDATTCHIVVLRHTGNGATCLTHCDGTDTKAEVSLIMSSIKSFSDHTQRGRLEVHLVGGFSDDRQLSQKLTHQLLSEFDRQEDDIHLVTLCVTELNDREENENHFPIIYGIAVNVKTAEIYRASFPDRGPEEELRAARVLTGGPMISIYDAKTEQLRIGPYSWMPFPHVDFWLQQDDKQILENLSTSPLAEPPHFVEHIRSTLMFLKKYPSPTNTLFPGNKALLYKKNEDGLWKEISSGGET
What is the function of this protein?
N-terminal asparagine deamidase that mediates deamidation of N-terminal asparagine residues to aspartate.  Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn.  These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH).  Conversion of the resulting N-terminal asparagine to aspartate by NTAN1/PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule.  This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position.
What are the official names of this protein?
Protein N-terminal asparagine amidohydrolase, Protein NH2-terminal asparagine amidohydrolase, PNAA, Protein NH2-terminal asparagine deamidase, PNAD, Protein N-terminal Asn amidase, Protein NTN-amidase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_STRP6
Sequence: MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGRTLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATGEVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNVLLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAICGDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQFNESDLEAIINDKA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCA_SHIBS
Sequence: MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMEALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVVVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSEILARTLAKQEAEQLARSKAASASENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYGA_STRPQ
Sequence: MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFEKFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGFPLLDEATRAILLAEDANKSI
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_SHESH
Sequence: MKFVDEAVIRVEAGDGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADESFNTLIDFQFERFHRAERGKNGRGRDCTGHGGEDLVLKVPVGTRAIDEETEESLGDLTAHGQRMLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELMLLADVGLLGMPNAGKSTFIRSVSRAKPKVADYPFTTLVPNLGVVNPRHGQSFVIADIPGLIEGAADGAGLGVRFLKHLERCRVLLHLVDIDPIDGSDPIESARAIVGELEKHSPKLASKPRWLVINKKDLLLEEELQERIDHIVKELEWKGEVFTISAYNREGTEELSLKLVDFIDSLPEEEEVDVEAEVEFKWDNYHKDSDSLNEDFDDSDDDDFDDDDYDVEVIYQR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.