PharMolix/UniProtQA huggingface dataset:
Protein: RECR_AZOVD
Sequence: MSFSPLIRQLIDALRILPGVGQKTAQRMALHLLERDRSGGLRLAQALTQALEHVGHCRQCRTLSEDELCPQCADPRRDDSLLCVVQGPMDVFAIEQTGYRGRYFVLKGHLSPLDGLGPEAIGIPELLARVEQGAFEEVIIATNPTVEGEATAHYIAQTLASSDVTVSRIAHGVPLGGELELVDGGTLSHALAGRRPIDL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: Y672_METJA
Sequence: MRLSKEFIGLGIITASLIFGSSLPDIYKGIVILIVAGCLWFFELLPLPVTSLAIPIMAVFLGIFNLKEALTYFAHPIIFLFLGGFMLAQALKNHNLDKFIAYKLLNYGKDFKTTCFLMFLSAYFLSMWISNTSATLILLPIALGLLHKKTGKLRDFLLLGVAYSASIGGIATIIGSPPNAIASSYLDYGFFSWFKVGFPISLLLFLICTLTLYIYFKKWIPKEDIAIQARMELSRNAYKLLVIFVLIASLWIISDYLSEIFNVQYFDSVIAIFAIILLFVFNLVEVNDFKKIDWGTLILFGGALCLGGVIVKSGANTFLSEKLIAILGNLTPIVLLFLVVTITIILTNFISNTGLTGIIVPILFGVSLGIPKEILILAVGMSASCSFILPVGTPPNAIVYSEGVKKEEMMKIGMILSILSAAVITLYSILYL
What are the official names of this protein?
Uncharacterized transporter MJ0672.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBE2C_BOVIN
Sequence: MASQNRDPVAASVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKDKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVSSQDP
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination.  Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis.  Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 C, (E3-independent) E2 ubiquitin-conjugating enzyme C, E2 ubiquitin-conjugating enzyme C, Ubiquitin carrier protein C, Ubiquitin-protein ligase C.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: UBID_PROMH
Sequence: MKYRDLRDFLSLLEEKGELKRITFEIDPYLEMTEIADRTLRAGGPALLFENPKGFDMPVLCNLFGTPERVAMGMGQDDVKALHEVGKLLAFLKEPDPPKGFRDLFDKLPKFKQVLNMPTKRLSKAPCQEVVLTGDDVDLTKIPVMHCWPEDAAPLITWGLTVTRGPFKERQNLGIYRQQVLGKNKVIMRWLSHRGGALDFQEWCQKHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGNKTEVVKCLSNDLEVPASAEIILEGYIEPGELAPEGPYGDHTGYYNEIDSFPVFTITHLTRRKDAIYHSTYTGRPPDEPAVLGVALNEVLVPILQKQFPEIVDFYLPPEGCSYRLAVVTMKKQYAGHAKRVMMGVWSYLRQFMYTKFVIVCDDDVNARDWKDVIWAITTRMDPARDTIMMENTPIDYLDFASPVSGLGSKMGLDATNKWPGETEREWGRPIVMTDEIKQRVDTIWEQLDIVK
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CALGL_TROCA
Sequence: MAATLTPEQITEYKGIFEMFDEEGNGLVKTDDLESLMSLIGINPTKRDLANMAKDVDKDKKGTFNCEGFLVLMGIYHEKSKNQDEELRAAFKVFDKEHKGYIEWDTLKYVLMNAGEPLNEHEAELMMKEADKDGDGTIDYEEFVAMMTGESFKLTQ
What is the function of this protein?
May be involved in the cellular control mechanism of the secretion of toxins from the gland into the venom.
What are the official names of this protein?
Calglandulin.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family. Calglandulin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Not found in venom.
Protein: TALB_SALTY
Sequence: MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSSDRAQQVVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRIIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVYLISPFVGRILDWYKANTDKKDYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEILELAGCDRLTIAPALLKELAESEGAIERKLSFSGEVKARPERITEAEFLWQHHQDPMAVDKLADGIRKFAVDQEKLEKMIGDLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase B.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF2A_CHICK
Sequence: MAPPAPLLAVRGSEGLFMVNGPPSFTESAVFQRDSGRNCKAVAFSKDGSLFAWCNGEKVNIVNVTSAGLLRSFDLPKVVCLEFSPKNNILATWQAYSAAKDGTAGAPNLQLYDVKTGKCLKSFIQKKMQNWCPCWADDESICARNVNNEVHFFENNNFNTIANKLHLQKVNDFVLSPGAQPTKVAVYVPGSKGAPSFVRLYQYPNFGGPQSALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNGESAIVQLPKNGPIYDVVWNPNSVEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCPDGEHIVTATCAPRLRVSNGYKIWHYTGSVLHNYEVPSNEEMWQVSWQPFLDGVFPVKAVKYQAVPSELPSAEPKPAQAYRPPALRNKPVTSSKLHEDEPPQNMKPQSGSSEKPLSKTALKNQKKHEPKKAAKQEAKADCSQESTQSSASQNTPRSAVPVVTSGDPEIDKKIKNLKKKLKAIEQLKEQAAAGKQLEKNQLEKIQKESALLQELEDLELGL
What is the function of this protein?
Functions in the early steps of protein synthesis of a small number of specific mRNAs.  Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits.  In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
What are the official names of this protein?
Eukaryotic translation initiation factor 2A, eIF-2A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EIF2A family.
Protein: RNPA_THEPX
Sequence: MRRKIVKIKKSYEFKKVYSNGKSVANQFVVMYYMENNLGFNRVGYSVSKKIGKSVVRNRVRRLLHESFRLLDIEIKTGFDIIFVARGKIVEADFHTLKNSMRKLIMKTPLYAGNEK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: LYS4_YEAST
Sequence: MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
What is the function of this protein?
Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
What are the official names of this protein?
Homoaconitase, mitochondrial, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL32_CORGB
Sequence: MAVPKRRMSRANTRMRRSQWKADNVALQEVKIDGQTVRIPRRLVKAAQLGLVDVEQF
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SODF_COXBU
Sequence: MAFELPDLPYKLNALEPHISQETLEYHHGKHHRAYVNKLNKLIEGTPFEKEPLEEIIRKSDGGIFNNAAQHWNHTFYWHCMSPDGGGDPSGELASAIDKTFGSLEKFKALFTDSANNHFGSGWAWLVKDNNGKLEVLSTVNARNPMTEGKKPLMTCDVWEHAYYIDTRNDRPKYVNNFWQVVNWDFVMKNFKS
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: XYOA_STRSI
Sequence: MSTAVTNWAGNITYTAKEVHRPATAEELADVVARSAWGACAGAAGHSFNEIADPGPDGVLLRLDALPAETDVDTTARTVRVGGGVRYAELARVVHAHGLALPNMASLPHISVAGSVATGTHGSGVTNGPLAAPVREVELVTADGSQVRIAPGERRFGGAVTSLGALGVVTALTLDLEPAFEVGQHLFTELPLRGLDFETVAAAGYSVSLFTDWREPGFRQVWLKRRTDQELPDFPWARPATVALHPVPGMPAENCTQQFGVPGPWHERLPHFRAEFTPSSGAELQSEYLLPRAHALDALDAVDRIRDTVAPVLQTCEVRTVAPDEQWLGPSHGRDTVALHFTWVKDTEAVLPVVRRLEEALDAFDPRPHWGKVFTTSAAALRARYPRLADFRALARELDPSGKFTNTFLRDLLDG
What is the function of this protein?
Oxidase that performs selective oxidation of the terminal primary hydroxyl group of several alditols, with a reduction of O2 to H2O2.  Shows highest activity on xylitol and D-sorbitol, and to a lesser extent, can also use galactitol, D-mannitol, and D-arabitol as substrates in vitro.  Is not active on D-glucose, D-xylose, D-galactose, D-mannose, D-fructose, L-sorbose, L-fucose, myoinositol, glycerol, ethyl alcohol, and meso-erythritol.
What are the official names of this protein?
Alditol oxidase, Xylitol oxidase.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: PETG_MESVI
Sequence: MVESLLSGIVLGMIPITLAGLFVTAYLQYRRGDQLKI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AFP_PENRW
Sequence: MHITSIAIVFFAAMGAVASPIATESDDLDARDVQLSKFGGECSLKHNTCTYLKGGKNHVVNCGSAANKKCKSDRHHCEYDEHHKRVDCQTPV
What is the function of this protein?
Antifungal protein that acts as an inhibitor of growth of human pathogenic molds and yeasts.
What are the official names of this protein?
Antifungal protein B.
What is the protein family that this protein belongs to?
Belongs to the antifungal protein pafB family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL1_THIK1
Sequence: MAVKTYQAGVKEYRQTYWMPEYTPLDTDLLACFKITPQAGVDREEAAAAVAAESSTGTWTTVWTDLLTDMDYYKGRAYRIEDVPGDDTCFYAFIAYPIDLFEEGSVVNVFTSLVGNVFGFKAIRALRLEDIRFPIAYVKTCNGPPNGIQVERDVINKYGRPLLGCTIKPKLGLSGKNYGRAVYECLRGGLDFTKDDENINSQPFMRWKQRFDFVQEATLKAEQETGERKGHYLNVTAPTPDEMFKRAEYAKEIGAPIIMHDYITGGFCANTGLAQWCRDNGMLLHIHRAMHAVLDRNPHHGIHFRVLTKILRLSGGDHLHTGTVVGKLEGDRASTLGWIDLLRESYVPEDRSRGIFFDQDWGSMPGAFAVASGGIHVWHMPALVTIFGDDSVLQFGGGTLGHPWGNAAGAAANRVALEACVQARNEGRQVEKEGREILTAAAQHSPELKIAMETWKEIKFEFDTVDKLDVTNK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: DJLA_HAEIN
Sequence: MEFIGKIIGVFLGWKVGGFFGAIAGLILGSIADKKLYELGSVSSSFFKKKTTRQDLFMQTSFAVLGHLSKSKGRVTEEDIQLANQLMIQLKLDDAGRKLAQDAFRRGKESDFPIRQVIREFRIGCGQRADLLRMFLQVQVQAAFADSELHENEKEVLYVIAEELGLSRMQFEQMIAMEMAARAFTQGGFYQKYQQGAYQGGYQYQQQNSGGYQHASGPTLNDAYKVLGVTESDEQSTVKRAYRRLMNEHHPDKLVAKGLPPEMMEMAKEKTQQIQAAYDLICKAKGWK
What is the function of this protein?
Regulatory DnaK co-chaperone.  Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway.  The colanic acid capsule may help the bacterium survive conditions outside the host.
What are the official names of this protein?
Co-chaperone protein DjlA.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type III membrane protein.
Protein: APT_STRPI
Sequence: MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYATDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIGDYDYKVLMHY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHCB2_MICDP
Sequence: MLDAFTKVVSQADTRGAYISDAEIDALKTMVAAGSKRMDVVNRITGNASTIVANAARALFEEQPQLIAPGGNAYTNRRMAACLRDMEIILRYVTYAVFAGDASVLDDRCLNGLRETYQALGVPGASVSTGVQKMKEAAIAIANDPSGVTRGDCSSLMSELGSYFDRAAAAVG
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
C-phycocyanin-2 beta subunit.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of the phycobilisome rod.
Protein: YADX_ECOLI
Sequence: MERASKMPSSYLYDQ
What are the official names of this protein?
Protein YadX.
Protein: PYRH_NEIG1
Sequence: MTQQIKYKRVLLKLSGESLMGSDPFGINHDTIVQTVGEIAEIVKMGVQVGIVVGGGNIFRGVSAQAGSMDRATADYMGMMATVMNALALKDAFETLGIKARVQSALSMQQIAETYARPKAIQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEMNCDVMLKATNVDGVYTADPKKDPSATRYETITFDEALNKNLKVMDATAFALCRERKLNIVVFGIAKQGSLKRVITGEDEGTLVHC
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_BPT4
Sequence: MQKTNPGLQRLFQIPTFTLSNSDLTCEMKVKIADTARYSLKQNPNQDKAEVIERCRIAVYAEFFVADWLSGYVNKGQEDVDDPYTYAWDVLAHPKYCGLRVEVKTHQTDSRWISVTTGCSGEYPYGSGINLGPILNHQVADCIIIFNTKEIHPGVIQYTPKFIGDREDLRKVVRKSNYNGWYLSI
What is the function of this protein?
Cleaves single-stranded DNA in a dC-specific manner.  The cleavage occurs exclusively at the 5'-proximal position (dC1) within a dCs tract having a minimal size of 6 bases.  These specific cleavages may have a detrimental effect on the replication of host dC-containing DNA.
What are the official names of this protein?
Endonuclease IV, Deoxyribonuclease IV.
Protein: CED9_CAEBR
Sequence: MVDSMDMANSSQNTFRRRTMATSEMREFLSTKDAEPNNFGMQTIPESPTPSTPTRRMSIGDSTRIYDWEEPRFNIQGFVVDYFTYRIAQNGLDWYDAPALPDGVQKEHEMMRSLGTIFEKRHMEMFENFSEQLLAVPKISFSLYQEVVQTVGNSSNTPCPMSYGRLIGLISFGGMVAAKMMESAELQGQVRNLLMYTSLFIKTRIRQSWKEHNRSWADFMKLGQQMKEDYEKEKDAEEGKRLKSWSIIGASVIAVIVCGRIIFSFK
What is the function of this protein?
Plays a major role in programmed cell death (PCD, apoptosis).  egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3.  During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway.
What are the official names of this protein?
Apoptosis regulator ced-9, Cell death protein 9.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Perikaryon. Synapse. Endomembrane system; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein. Note=Intracellular membranes, mitochondrial, and perinuclear region. Localizes to synapses of DD motor neurons. Synaptic localization is dependent on axonal mitochondria.
Protein: YD344_YEAST
Sequence: MAFLSWTFFPSFFHFLERNRFFLTFATQLHYLNPFYILSFRVEWHQIWENLAYSDTNTFFHEYCWKIFPCLSAGIRNNGCCDAAKGQGKNKQHTPKQEEEIPNTSLRRHRSCCNMFTCSSPCYYLEINVGVIGVRRPVLSEEQRKNC
What are the official names of this protein?
Uncharacterized protein YDR344C.
Protein: MGDP1_MOUSE
Sequence: MTRLPKLAVFDLDYTLWPFWVDTHVDPPFHKSSDGTVRDRRGQNIQLYPEVPEVLGRLQSLGVPVAAASRTSEIQGANQLLELFDLGKYFIQREIYPGSKVTHFERLHHKTGVPFSQMVFFDDENRNIIDVGRLGVTCIHIRDGMSLQTLTQGLETFAKAQAGL
What is the function of this protein?
Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.
What are the official names of this protein?
Magnesium-dependent phosphatase 1, MDP-1.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: CR4AA_BACTI
Sequence: MNPYQNKNEYETLNASQKKLNISNNYTRYPIENSPKQLLQSTNYKDWLNMCQQNQQYGGDFETFIDSGELSAYTIVVGTVLTGFGFTTPLGLALIGFGTLIPVLFPAQDQSNTWSDFITQTKNIIKKEIASTYISNANKILNRSFNVISTYHNHLKTWENNPNPQNTQDVRTQIQLVHYHFQNVIPELVNSCPPNPSDCDYYNILVLSSYAQAANLHLTVLNQAVKFEAYLKNNRQFDYLEPLPTAIDYYPVLTKAIEDYTNYCVTTYKKGLNLIKTTPDSNLDGNINWNTYNTYRTKMTTAVLDLVALFPNYDVGKYPIGVQSELTREIYQVLNFEESPYKYYDFQYQEDSLTRRPHLFTWLDSLNFYEKAQTTPNNFFTSHYNMFHYTLDNISQKSSVFGNHNVTDKLKSLGLATNIYIFLLNVISLDNKYLNDYNNISKMDFFITNGTRLLEKELTAGSGQITYDVNKNIFGLPILKRRENQGNPTLFPTYDNYSHILSFIKSLSIPATYKTQVYTFAWTHSSVDPKNTIYTHLTTQIPAVKANSLGTASKVVQGPGHTGGDLIDFKDHFKITCQHSNFQQSYFIRIRYASNGSANTRAVINLSIPGVAELGMALNPTFSGTDYTNLKYKDFQYLEFSNEVKFAPNQNISLVFNRSDVYTNTTVLIDKIEFLPITRSIREDREKQKLETVQQIINTFYANPIKNTLQSELTDYDIDQAANLVECISEELYPKEKMLLLDEVKNAKQLSQSRNVLQNGDFESATLGWTTSDNITIQEDDPIFKGHYLHMSGARDIDGTIFPTYIFQKIDESKLKPYTRYLVRGFVGSSKDVELVVSRYGEEIDAIMNVPADLNYLYPSTFDCEGSNRCETSAVPANIGNTSDMLYSCQYDTGKKHVVCQDSHQFSFTIDTGALDTNENIGVWVMFKISSPDGYASLDNLEVIEEGPIDGEALSRVKHMEKKWNDQMEAKRSETQQAYDVAKQAIDALFTNVQDEALQFDTTLAQIQYAEYLVQSIPYVYNDWLSDVPGMNYDIYVELDARVAQARYLYDTRNIIKNGDFTQGVMGWHVTGNADVQQIDGVSVLVLSNWSAGVSQNVHLQHNHGYVLRVIAKKEGPGNGYVTLMDCEENQEKLTFTSCEEGYITKTVDVFPDTDRVRIEIGETEGSFYIESIELICMNE
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects.
What are the official names of this protein?
Pesticidal crystal protein Cry4Aa, 135 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryIVA(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: CH10_NITOC
Sequence: MKIRPLHDRVIVRRMEEEKTSSGGIVIPDTAAEKPIRGEVVAVGNGKILESGEVRALDVKVGDKVLFGKYSGTDVKVESEELLVMREDDIMAVLEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_ECOLC
Sequence: MLNPIVRKFQYGQHTVTLETGIMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRVYTGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRIRLSIKEATEQSQPAAAPEAPAAEQGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_YERE8
Sequence: MSSTKKPLVLTILDGYGHREEQQDNAILNAKTPVMDRLWQQQPHTLIAASGLDVGLPDGQMGNSEVGHVNLGAGRIVYQDLTRLDKEIKDGDFFTNPTLTAAVDKAVKAGKAVHIMGLLSAGGVHSHEDHILAMVELAAKRGATAIYLHAFLDGRDTPPRSAEPSLKRFTEKFAALGKGRIASIIGRYYAMDRDNRWDRVQLAYDLLTQAKGEFTADNAVVGLQAAYARNENDEFVKPTVIQAAGEPDAAMNDGDALIFMNFRADRARQITRTFVNADFDGFKRDKVVNFGDFIMLTEYAADIKVACAYPPASLENTFGEWLMKHDKTQLRISETEKYAHVTFFYNGGVEEPFKGEDRILINSPKVATYDLQPEMSSAELTEKLVGAIASGKYDVIICNYPNGDMVGHTGDYDAAVKAVETLDNCIEQVVAAVQAVDGQLLITADHGNAEQMRDPATGQAHTAHTSLPVPLIYVGNKEVKAVEGGKLSDIAPTMLSLMEMEIPQEMTGKPLFIVE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: GMPR2_HUMAN
Sequence: MPHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVNPIFSEAC
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (PubMed:12009299, PubMed:12669231, PubMed:16359702, PubMed:22037469).  Plays a role in modulating cellular differentiation (PubMed:12669231).
What are the official names of this protein?
GMP reductase 2, GMPR 2, Guanosine 5'-monophosphate oxidoreductase 2, Guanosine monophosphate reductase 2.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.