PharMolix/UniProtQA huggingface dataset:
Protein: BORA_HUMAN
Sequence: MGDVKESKMQITPETPGRIPVLNPFESPSDYSNLHEQTLASPSVFKSTKLPTPGKFRWSIDQLAVINPVEIDPEDIHRQALYLSHSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSQCHSSKCTNINSDSPVGKKLTIHSEKSDAACQTLLSLPVDFNLENILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPSASPGSPHSGVQTSLEMFYSIDLSPVKCRSPLQTPSSGQFSSSPIQASAKKYSLGSITSPSPISSPTFSPIEFQIGETPLSEQRKFTVHSPDASSGTNSNGITNPCIRSPYIDGCSPIKNWSPMRLQMYSGGTQYRTSVIQIPFTLETQGEDEEDKENIPSTDVSSPAMDAAGIHLRQFSNEASTHGTHLVVTAMSVTQNQSSASEKELALLQDVEREKDNNTVDMVDPIEIADETTWIKEPVDNGSLPMTDFVSGIAFSIENSHMCMSPLAESSVIPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTCEVESKSQAFNMKQDHTTQRCWMKTASPFQCSSP
What is the function of this protein?
Required for the activation of AURKA at the onset of mitosis.
What are the official names of this protein?
Protein aurora borealis, HsBora.
What is the protein family that this protein belongs to?
Belongs to the BORA family.
Protein: MRAZ_MESH7
Sequence: MFGTVFRILDEKNRIVMPPAFRNELEGDFYISANLEKILEIRSQTEFDLLAQKIGKANSLDPKLRDFARYFFGNTVKVSADKQGRFLIPKNLLDLATISKNLYLIGVNNKIEIWPEQRYEQFYAKFSDSEMTADLEKELLKSGVEL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PUR9_STAEQ
Sequence: MKKAILSVSNKSGIVEFAKALTNLDYELYSTGGTKRVLEDANINIKSVSELTQFPEIMDGRVKTLHPAVHGGILADRDKEHHLEQLREQHIDLIDMVVVNLYPFQQTVAQPDVTETDAVENIDIGGPTMLRAAAKNFKHVTTIVHPSDYNEVIERIKNHQLDEAYRKSLMVKVFQHTNEYDHAIVNYFKDNKETLRYGENPQQSAYFVRTSDSKHTIAGAKQLHGKQLSFNNIKDADAALSLVKKFNEPTAVAVKHMNPCGVGIGQSIDEAFQHAYEADNQSIFGGIIALNRTVDVKLAEALHSIFLEVVIAPQFTEEALKILTQKKNIRLLQIDMTIDNAEQEFVSVSGGYLVQDKDNKDVTRNDMTVATDTQPTEAQWEAMLLGWKVVSAVKSNAVILSNNKQTVGIGAGQMNRVGSAKIAIERAIEINDNVALVSDGFFPMGDTVEYAAEHGIKAIIQPGGSIKDQDSIDMANKYGITMVMTGMRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: MATK_IRIDM
Sequence: MEELQGYLEKDRSRQQPLLYPLLFQEYIYALAHDRGLKGSLFYEPTEVFGYDSKFSLALVKRLIIRIYQQNFFLSVVNDSNKNRFVSHHHNNFCYSHFYSQMISEGFAILVEIPFSLRLVSYFEKKEIPKSHNLRSIHSFFPFLEDKLLHSDYVSDIIIPHPIHMEILVQILQCWIQDVPLLHFLRFFLHKYHNWNSFLITPKKSIYVFSKENKRLFRFLYNSYVSECEFLLVFLRKQSSYLRLTSFGTFLERRHFYVKMEHLQMQHLILIVVCRDYFQGTLWSFKDPFMHYVRCQGKAVLASKGTHFLMKKWKYNFVNLWQYYFHFWYQSYRIHINQLSNYSFYFMGYLSSLLKNSSTVRNQMLENSFLIDTVTNKFETIVPVIFLIGSLSKAQFCTVSGHPISKPIWADLSDSEIIERFGRMCRNLSHYHSGSSKKQGLYRIKYILRLSCARTLAGKHKSTVRTFLRRLGSGLLEEFFTEEEQVLSLILPKTIPFTFYGSKKERIWYLDIIRINDXVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NTP1_TOXGO
Sequence: MWLPVYVPLLLVFGVSLSLPQGSLGTDSSSLRGVDADTEKRINVGKKHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIGAGKRFAGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEKQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARCMIDEYGVKQCRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVNNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIKGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMIVTGGGMLAAINTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRNAYEAGYSHNL
What is the function of this protein?
May perform an important processing step in the conversion of high energy nucleotides prior to uptake by the parasite and may contribute to intracellular survival and virulence.  NTPAse-I has a specific activity 4. 5-fold higher than NTPAse-II in hydrolysis of ATP.  The primary difference between these isozymes lies in their ability to hydrolyze nucleoside triphosphate versus diphosphate substrates.  While NTPAse-II hydrolyzes ATP to ADP and ADP to AMP at almost the same rate, NTPAse-I hydrolyzes ADP to AMP at a much slower rate (0. 7% of the rate for ATP).
What are the official names of this protein?
Nucleoside-triphosphatase 1, NTPase-I, Nucleoside triphosphate hydrolase 1, Nucleoside-triphosphatase I.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Secreted. Parasitophorous vacuole. Note=Found in host cell parasitophorous vacuole.
Protein: PTP2_ENCCU
Sequence: MLLLLAITAVVSATMVHPSAVVPQPAAPLHVVPPQQQMGMVNGCTSKKLEGAEIMRRNMIECQKRSSEATKAMIERANEKAVESFNKEVSKGPSQKDGGQCIEKAVQGTDRCILAGIIDKAVNKRKYRISDVENSTSLYRGDKLIALIVNVDYGLQPITKPKKKKSKIMANLPQPKREMYFNQIGQLVGARGTFPQENKEDCKPCEGPKKTVETTSEKCNLGCELKGTSALISKAIQKKEVKDTKEGEKSASQDSDGEGTAEDAEVQQPSADGEGLE
What is the function of this protein?
Involved in formation of a polar tube through which the infectious agent is passed on to the host cell.
What are the official names of this protein?
Polar tube protein 2.
What are the subcellular locations of this protein?
Spore polar tube.
Protein: LEU3_XANOM
Sequence: MSKQILILPGDGIGPEIMAEAVKVLQRIDTQHGLGFELVYDELGGAAYDKYGSPLADETLERARAADAVLLGAVGGPQWDTIDPSLRPERGLLKIRSQLGLFANLRPALLYPQLADASTLKPEVVAGLDLLILRELTGGIYFGQPRGNRTLDNGERQAYDTLPYSESEICRIAKAGFEMARLRGKKLCSVDKANVLASSQLWRAVVEEVAKDYPDIALSHMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDQASMLTGSIGMLPSASLDANSKGMYEPCHGSAPDIAGKGIANPLATILSVAMMLRYTFAQADAADAIERAVGKVLDQGLRTADIWSEGTTKVGTVAMGDAVVAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_BORPA
Sequence: MQETTVKRDGASPSDAGTPATTAQGLGKLYIRTFGCQMNEYDSDKMADVLRADQGLELTDNPEDADVILFNTCSVREKAQEKVFSDLGRVQHLKKQNPNLVIGVGGCVASQEGEAIVKRAPYVDVVFGPQTLHRLPDLIKRRRAQGVSQVDISFPEIEKFDALPPPRVDGATAFVSIMEGCSKYCSFCVVPYTRGEEVSRPFDDVLLEIADLADQGVKEVTLLGQNVNAYRGAMGDSGEIADFAMLLEYVHEIPGIERIRYTTSHPKEMTQRMVDAYARLPKLVSFLHLPVQAGSDRVLAAMKRGYTALEFKSVVRRLRAARPSLTLSSDFIVGFPGETEEDFQKTMKLIEDVGFDTSFSFVYSRRPGTPAADLHDDTPQDVKLRRLQQLQALINQQAAAIAQGMIGTRQRVLVEGPSRRDPNELMGRTENNRIVNFPGVPRLIGHMVDVVVTHAHTNSLRGRVAGIERDTSGAE
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSC1_HUMAN
Sequence: MSASPDDLSTGGRLQNMTVDECFQSRNTVLQGQPFGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKTSPSETSLEMERRDKGFCSWFFNSITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYTGSVLDWSSHFARTTIVNVSTESKLLWLHSLLSFFYFITNFMFMAHHCLGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMRGRLFYTAKAKKTGKVMIRIHPCARLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELNRVPLKRLDLIFVTFQDSRMAKRVRKDYKYVQCGVQPQQSSVTTIVKSYYWRVTMAPHPKDIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMNTIDMYNVTRPIEKLQNPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITAALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLNEQIHMAAVSQAIFAPLLGLFWMLFFSILRLGSLHAITIFSLSTLLIAMVIAFVGIFLGKLRMVADYEPEEEEIQTVFDMEPSSTSSTPTSLLYVATVLQEPELNLTPASSPARHTYGTMNNQPEEGEEESGLRGFARELDSAQFQEGLELEGQNQYH
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel (PubMed:24503647).  Required for the functional integrity of the kidney glomerular filtration barrier (By similarity).
What are the official names of this protein?
Calcium permeable stress-gated cation channel 1, Transmembrane protein 63C.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURB_CERS1
Sequence: MMPPVRGTLTQGRILADLTWLRVGGPADWLFQPADEADLVQFLGALDPAVPVFPMGVGSNLIVRDGGLRAVVIRLGRGFNAIRIEGDRVIAGAAALDAHVARRAAEAGRDLTFLRTIPGSIGGAVRMNAGCYGSYVADHLIEVRAVTREGRAVTLPAAELGLAYRQSALPEGCVLTEATFRAEAGDPAELARRMDEQIARRDSSQPTKERSAGSTFRNPAGFSSTGRADDTHELKAWKLIDEAGLRGARRGGAQMSEMHSNFLINAGGATAADLEGLGEEVIKRVFQSSGIRLEWEIMRVGELPVNKE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLB_ECOSM
Sequence: MSFDLIIKNGTVILENEARVVDVAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVCHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ
What is the function of this protein?
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
What are the official names of this protein?
Allantoinase, Allantoin-utilizing enzyme.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
Protein: DNAJ_CLOB8
Sequence: MANKDYYELLGLQKGASDDEIKRAFRKLAVKYHPDRNQGNAEAEEKFKEINEAYQVLSDPEKKAKYDQFGSAAFDGSGGFGGGGFGGFDGFDMGGFGDIFESFFGGGGSNSRRRNGPVRGNDIEYTITLTFEEAVFGVEKEISVTRNENCEHCHGSGAEPGTNAKTCPTCSGSGQVRVQRQTPLGSFVSTSTCDTCRGTGKIIEKPCSECRGKGSVRKTRKIKVNIPAGVDTGNVMPLRGQGEHGLRGGSPGDLYVRINVTPSKVFTRKGNDVYIDAHISMPKAALGTEITVATVDGNVKYTVPPGTQSGTMFRLKGKGIQRVNSNGKGDQYVKVIVDIPKTLNKEQKEALYDFMRASGEEFDEANVPKKKLFGKNK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SXA_MICFL
Sequence: MKTLLLTLVVVTIVCLDLGNSLKCYSSRTETMTCPEGEDKCEKYAVGLMHGSFFFIYTCTSKCHEGAYNVCCSTDLCNKSSTSG
What is the function of this protein?
Postsynaptic neurotoxin that produces potent, and completely reversible, postsynaptic neuromuscular blockade, as well as broad spectrum inhibition of human muscle and neuronal nicotinic acetylcholine receptors (nAChRs).  Inhibition is potent or moderate, depending on the receptor (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE (IC(50)=2. 56 uM), alpha-4-beta-2/CHRNA4-CHRNB2 (IC(50)=1. 8 uM), alpha-7/CHRNA7 (IC(50)=7 uM), and alpha-3-beta-2/CHRNA3-CHRNB2 (IC(50)=12. 6 uM)) (PubMed:31877243).  Acts as a competitive antagonist of ACh (PubMed:31877243).  Binds to chicken muscle-type nicotinic acetylcholine receptor (AChR) with high potency compared with the cloned human receptor (PubMed:31877243).  Unlike short-chain alpha-3FTxs that only bind to muscle nAChRs, this toxin utilizes dimerization to expand its pharmacological targets to block neuronal nAChRs (PubMed:31877243).
What are the official names of this protein?
Fulditoxin, Micrurus fulvius dimeric neurotoxin, SIGMA-neurotoxin, Three-finger toxin 3a, 3FTx 3a, Three-finger toxin 9a, Three-finger toxin 9d, Three-finger toxin 9e.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GCST_ECOUT
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYSQEMDETISPLAANMGWTIAWEPADRDFIGREALEAQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: IL4RA_RAT
Sequence: MGWLCTKFLSSVSCLILLWVTGSGGIKVLGDPTCFSDYIRTSTCEWQLDSTVDCSSQLLLDYRLLFEFSENLTCTPKNSADTVCVCQMAIEEPIQADTYWLELWSERGQLWQGSFKPSDNVKPPAPDNLTLHTNVSNALLLMWSNPYPSNNFLHKGLICMVNISREDNPAEFKVYNVTYTEPKLSFPVNTLTSGVRYRARVRVLSQSFPGIWSEWSPSITWYNHFQLPLLQRLPLGVSISCICILLFCLTCYFSIIKIKKIWWDQIPTPARSPLAAIIIQDTKVSLWEKQTRSQESTKSRHWKTCLTKLLPCLLEHRVKKERESPKAAKTKPLQSPEKAGWYPAEVSRTVLWPENVHVSVVRCMELFEAPVQNVEEEEDEMVKGDLSMSPENSGGGFQESQADIMARLTENLFSDLLGAENGGVGQSSMAESSSLLPSESGQASTSWACFPTGPSETTCQVTGQQPPHPDPERATGTACTQVPLVISDNPAYRSFSDFSSPAPNPGELASEQKQAGHLEEGDLLSPVDPHSSGPPMQQAESWEQILHMSVLQHGTAGSTPAPTSGYQEFVQAVKQGASQDAGVPGVGPSGDTGYKAFSSLLSSSGVCTDTAAAGTDSGCGGYKPFQNPVPNQSPNSMPLFTFGLDMELPPSPLNSAPPNSTPECLGLELGLKGGTWLKAPPPSEQVPKPFGDDLGLGIVYSSLTCHLCGHLKQHHSQEEDGQIHVVASPGCGCCYDEKSPSLGNLSGTLESCPGEMSQEANLTLAPRTPSNLSGVGKGPGHSPVPSQTTEVPVGTLGVTVS
What is the function of this protein?
Isoform 2 (soluble form) inhibits IL4-induced spleen cell proliferation.
What are the official names of this protein?
Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: ASTA_SALNS
Sequence: MRVIRPVEHADIAALMQLAGKTGGGLTSLPANEATLAARIERALKTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARAVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAPGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: NADA_METB6
Sequence: MDDTALLQEEILRLKEKKNAILLAHNYQRPEVQDIADLTGDSLELARAAAAMQGDTIVFCGVDFMAETAAILAPDKTVLLPAADACCPMAEMVTAEELRFARARHPGAAVVCYVNTTAGVKAESDICCTSANAISVVNSLTEDRVIFVPDKNLGRYAARFTEKKVLPWEGFCLVHDRYTPDDVARAKDAHPGAAVVVHPECRPEVIDLADHVASTSGIIRYVQTSPGSEFIIGTEIGILHRLSKECPGKRCFPLSDKAVCVNMKKTTLVHVRDALVTGQPRITVPDEIASRARRAIGRMLAL
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_NITWN
Sequence: MSQEMTLQERMDGEGGSDPLRQAVKGAVAALAQAAIDISDLTCRGALAGITGQAQGRNTDGDVQKDLDVRADQIIRDALGKQPIAALASEEMEELDILNPGAPICVAFDPLDGSSNINTNMSVGTIFSIMPTPSDVNAAFRQAGSEQLAAGFVVYGPQTSLVLTLGQGVDIFTLDRVDRVFKLTGSAVKIPAEATEFAINASNRRHWDLPVRAYIDECLAGADGAGGKNYNMRWIGSLVAEAFRILIRGGIFLYPGDARDGYEEGRLRLVYEAHPMAFIVEQAGGGASTGRKRVLDLVPGSLHQRVPLIMGSIKNVQRLEHLHTVPDGALEANAPLFGNRGLFRV
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P5CR_MYCTO
Sequence: MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE
What is the function of this protein?
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase, P5C reductase, P5CR, PCA reductase.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK20_MORIN
Sequence: MTRIKRGYIARRRRTKIRLFASSFQGARSRLTRTITQQKIRALVSAHQDRGRQKRDFRRLWITRINAVIRANKVYYSYSTLIHHLYKRQLLLNRKILAQIAILNRNCLYMISNEILK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACEK_IDILO
Sequence: MTISPETLAKSILDGFHSHYRRFQVLTQGARERFLKRDWTAVVSAASERIHYYDHQVGTTAKKVERRVGTELDEGLWLATRQRYQQLLKFHPQAELAETFYNSVFCRVFDRAYFNNDYIFVETVLANHIPVPVENECHSYFPVVDGLEGTLTRVFEDIGLGGEFENFENDIEQLRDKFFERATETDIEAHNLRIDVLKSPFYRNKAAYIVGRVVTENNHYPFIVPVLINSQGKLYVDAFITRSDRMATIFGFARSYFMVETEAPSALVRFLKDLMPHKTLAELYSSVGFHKQGKTEFYREFLHHLRRTDDQLSAAPGVKGMVMTVFTLPSFPYVFKVIKDRLGGTKEFGRQTVIDRYRMVKRHDRVGRMADTLEFVDVALPLKRISADLLDEFKQTIANSISIEGDTLVIHQLFVERRMTPLNLYLEYANDEEVDAAMDDYGRALKEMMAANIFPGDMLLKNFGVTRHKRVVFYDYDEVRYLTDMSFRRLPENDWEVSYAPDDVFPQQLAQFAVPQAKYRNKLLKRHPELIDSAYWCRVQKNIRKGELTDVFPYDADLRFTRRF
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_NATTJ
Sequence: MPRVKTGTNRRRRHKKVLKLAKGYRGTKGNLFRIANQQVMKSLTYAYRDRKQRKREFRRLWISRINAACRQNGISYNKFINGLKKAGVEINRKMLADMAVNDEQAFGELVDLAKKSV
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ACP_ECOBW
Sequence: MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_BRUSI
Sequence: MTTELHDDASGRLIVGLDVPTIAEAEKVVEELGNAVSFYKIGYQLVFAGGLDFAKSLVAARKKVFLDMKLLDIDNTIAKGVENVAKMGVSMLTLHAYPKAMRAAVEAARGSDLCLLGVTVLTSMDNADLREAGYSDNAETLVLKRARQAHEAGMGGIVASAVEAQAIRQAVGPDMAIVTPGIRPAGSEKGDQKRVMTPADALRAGASHLVVARPIVGAPDRKAAALAILKEMRSIGRS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: HIS6_STRMK
Sequence: MLSRRIIPCLDVRDGRVVKGVRFRDHVDMGDIAELAQRYRDQGADELVFYDIGASPEARSVDVAWIERIARLIDIPFCVAGGIDSVETARRVLFAGADKVSINSPALGRPELITELADEFGVQCVVVGVDSVRETDGQWRVRRFSGDPDKTQAVPLRTLDWIVEAQRRGAGEIVLNCMDSDGVRRGYDVVQLQQARALCQVPLIASGGAGAMEHFAEAFDQADVDGALAASVFHSGAIAIPELKRYLRGQQIEVRDVY
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_BRUSU
Sequence: MSAHDLKLEEIVNAETLRRKLNELADTADESYTSLPMRKVVLQTLKDALASGRANAEDMLMKDGGGTLCAKRLCYLMDTLIDILFEFATTRAYPTRNPSKAENMALVAVGGYGRGGLAQGSDIDLLFLLPYKQTPWGEQVVEYTLYMLWDMGLKVGHSTRNIDECIRLAREDMTIRTALLDARFLTGDKDLFRTLEIRFEEEIVKGTEPEFIQAKLAERDARHRKAGETRYLVEPNVKEGKGGQRDLHTLFWITKYFYRVKTKEELVKLGVLSRAELKLFNKAEDFLWAVRCHMHFATLKAEERLSFDIQPEIAQRLGYTAHPGQNYVERFMKHYFLVAKDVGDLTRIICAALEEQQAKHVPGFNRIFLTFSRRKRKLSDDGAFISENHRINIARPDIFRQDPVNMIRLFHLADRHGLEFHPEAMQSLTRSLKLINADLRENPEANRLFLEILTSPRNPELILRRMNESGVLGKFIPDFGKIVAMMQFNMYHHYTVDEHLLRCIAVLSEIEHGELKTEHPLSNHLITTIKRDRNLLYVTLLLHDIAKGRPEDHSIAGARIARRLCPRFGLTPSETETVEWLVREHLTMSMVAQSRDLNDRKTIIDFADTVQTMERLKLLLILTVCDIKAVGPGIWNGWKGQLLRTLFYETELVLTGGFSELSRAARDKQAREALAERLSDWPKEERDAYLALPYTNYFLTVSLDDQVRHAHFIRDADQQGRALVTMAKPHAFEAVTEITVLAPDHPRLLSVITGACAAAGGNIVDAQIFTTSNGRALDTILISREFDTDDDERRRAERVGKVIEDVLSGKAHLPDMLAKRTKPKKAARAFKVEPRVEINNTLSNKFTVIEVEGLDRPGLLSELTGLISDLSLDIASAHITTFGEKVIDSFYVTDLVGHKISNATRQGNIKRKLLALLGAENGARTNGRSPQAAA
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.