PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_STAA8
Sequence: MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: IF2_FINM2
Sequence: MEKIRVYELAKQLNVSTKDLMSKLKDNKIEVKSHMSTLDKDQIAKVKSFYEKQKKVQTSQNNSKSNDENKKITNKNTEKTTEKISTVDSNKQNNSNKRFKPKHPRNNDEESVSHFDKIKHKNKSEMNEKRDLNDKKKNKNFKNTKNKNSNNNKNSKNNKNNKNNDHNRKDEAIKHETKEPKKFIIQPTITVKDLSEKISVSISELIMKLMELGIMANQNQEIDFDTASLVAGEFDVIVEQDEVEDFDDDDVFNLDFEDKKEDLKERPPVITVMGHVDHGKTSILDRIRNSRVAGREAGGITQHIGAYTIRVNDKKIVFLDTPGHEAFTAMRSRGAQVTDVSILVVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKENANIERVKTELAENGLVPEDWGGDTVLVPVSARTGEGIDDLLEMILMVAEMEELKANPNRLAVGTVIEAQLDKGRGPTATILVQKGTLKHSDMVFSGQASGRIRAMFNDQGKQVKKAGPSTPVLILGLNEVPEAGDMIYAVKDEKEARNYAQKIKDHNREEQIKSSSTMNLDELFGKISDGETKDLNIIIKTDVKGTIDAIKQSLIKLSNEEVKVNIIHGAVGGITESDVNLASASSAIIIGFNVRPTQVAMDMAKNESIEIRTYRVIYDAIEDVKNAITGMLKPQYQEEVLGRATVRDTFKVPGVGTVAGVYVNTGKVTRNATVRLLRDEILIFEGPVSSLKRYKDDVKELTQGYEGGMGLENYNDIKPGDVLEAYVLNEVQR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAF9B_PONAB
Sequence: MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSKPTTPTIATPQTVSVPNKVATPMSVTSQRFTVQIPPSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEANPLKRKHEDDDDNDIM
What is the function of this protein?
Essential for cell viability.  TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes.  May have a role in gene regulation associated with apoptosis.  TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex.  TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription (By similarity).
What are the official names of this protein?
Transcription initiation factor TFIID subunit 9B.
What is the protein family that this protein belongs to?
Belongs to the TAF9 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LAC20_ORYSJ
Sequence: MVASLLCTVAVAVLAVAAVGGEAGVVEHTFVVHEMNVTHLCNTTKIFVVNGQLPGPTVDVTEGDTVVIHVVNKIPHGLTIHWHGVRQLRSCWADGAGFITECPIPPGSERTYRFNVTDQVGTLWWHAHVTCLRSTINGAFIIRPRDGKYPFPTPVKDVPIIIGEWWELDLVELDRRMRDGNFDDNPLSATINGKLGDLSNCSGIVEESFVLNVKHGESYLLRVINTAFFSEYYFKVAGHTFTVVGADGNYLTPFKTDMVTVAPGEAIDVLMVADAPPAHYHMIALANQPPEPDPQIPKYISRGLVRYTGVDANNNGLPVPMPIMPNQHNTMPSYYFHANLTGLMHPKHRRVPMHVDERIFIILGLGTICRGRNTTCKRQRSLETIEVATMNNVSFTHPNTTALLERYYDGTPEGVYTEDFPVRPPRPYNYTNPALIPPGPLEEVLEPTFKATKLKRFKYNTSVEIIFQSSTLLMSDSNPMHLHGYDVFLLAQGLGSFNAKRDIRKFNYHNPQLRNTILVPRGGWAAVRFITDNPGMWYLHCHFEFHIIMGMATAFIVEDGPTPETSLPPPPPEFKRCDAS
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-20, Benzenediol:oxygen oxidoreductase 20, Diphenol oxidase 20, Urishiol oxidase 20.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: YIPF1_MOUSE
Sequence: MAAVDDLQFEEFGDGATLLAANPDATTINIEDPSVSFGHQPRPPGSVGREEDEELLGNNDSDETELLAGQKRSSPFWTFEYYQTFFDVDTYQVFDRIKGSLLPVPGKNFVRLYIRSNPDLYGPFWICATLVFAIAISGNLSNFLIHLGEKTYHYVPEFQKVSIAATVIYAYAWLVPLALWGFLLWRNSKVMSMVSYSFLEIVCVYGYSLFIYIPTAVLWIIPQRVVRWVLVMIALGVSGSVLVMTFWPAVREDNRRVALATIVTIVLLHVLLSVGCLAYFFDAPEMDHLPAAITTPNQTVTAAKSS
What are the official names of this protein?
Protein YIPF1, YIP1 family member 1.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane. Late endosome membrane. Note=Mainly localizes within medial-/trans-Golgi and trans-Golgi network (TGN), while less so within cis-Golgi.
Protein: HAP28_DICDI
Sequence: MAGGKRGGKVAPTKTFGRDYERSKGKISRDRVYDEEDIIKRNQESDSDDNSGSESGSENETKNNNNKSKLGSDSSDDEPVIVSRNPNAKKPAAKRPPTTKKQQESDSEDDSDKESDSEDEIANPNRMKQVTKKLSEINVNAKVELSRREKEELARQAATQRQNEKQQKSDLERLQVIRKQREEAAKRKEEEKKANEEKMAERRRLGLA
What are the official names of this protein?
28 kDa heat- and acid-stable phosphoprotein homolog.
What is the protein family that this protein belongs to?
Belongs to the PDAP1 family.
Protein: KEFC_ECOHS
Sequence: MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NHP6_DEBHA
Sequence: MAPTEKKRTTRKKKDPDAPKRSLSAYMFFANENRDIVRAENPGISFGQVGKLLGEKWKALTPEDKIPYENKADTDKKRYEKEKAEYAKKNAA
What is the function of this protein?
DNA-binding protein that induces severe bending of DNA.  Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity).
What are the official names of this protein?
Non-histone chromosomal protein 6.
What is the protein family that this protein belongs to?
Belongs to the NHP6 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL3_CLOBJ
Sequence: MKKAILGKKLGMTQIFNENGKVIPVTVIEAGPCTVIQKKTVEKDGYEAIQVAFGDIREKLRNKPVKGHFAKAGVSVKRHIKEFKLEDLNSLEIGQEIKADVFEAGERVDISGVSKGKGFQGTIRRWNAHRGPMSHGSKFHRAVGSMGASSDPSRTFKNKRMPGHMGNVNTTVLNLEVVRIIPEKNLILIKGGVPGPNKGLVQIRNTVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DGK7_ARATH
Sequence: MEETPRSVGEASTTNFVAARPSAKTDDAVTMRGCGFANLALVGIDKEELRGRLAMPEYLRIAMRDCIKRKDSTEISDHLLLPGGAAADMAPHAPMVVFINPKSGGRHGPVLKERLQQLMTEEQVFDLTEVKPHEFVRYGLGCLDTLAAKGDECARECREKIRIMVAGGDGTVGWVLGCLGELHKDGKSHIPPVGVIPLGTGNDLSRSFSWGGSFPFAWRSAMKRTLHRATLGSIARLDSWKIVVSMPSGEVVDPPYSLKPTIEETALDQALDADGDVPPKAKSYEGVFYNYFSIGMDAQVAYGFHHLRNEKPYLAQGPVTNKIIYSSYSCTQGWFCTPCVNNPALRGLRNIMKIHIKKANCSEWEEIHVPKSVRSIVVLNLYNYGSGRHPWGNLRPKYLEKRGFVEAHCDDGLIEIFGLKQGWHASFVMAEIISAKHIAQAAAIRFELRGGDWKNAFLQMDGEPWKQPMKSDYSTFVEIKKVPFQSLMINGE
What is the function of this protein?
Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule.  PA is required for plant development and responses to abiotic stress and pathogen attack.  May be involved in the accumulation of PA during cold stress xhibits high specificity for 1,2-dioleoyl-sn-glycerol (1,2-DOG), 1-palmitoyl, 2-oleoyl-sn-glycerol (1,2 POG), 1-stearoyl, 2-linoleoyl-sn-glycerol (1,2-SLG) and 1-oleoyl, 2-palmitoyl-sn-glycerol (1,2-OPG).
What are the official names of this protein?
Diacylglycerol kinase 7, AtDGK7, DAG kinase 7, Diglyceride kinase 7, DGK 7.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
Protein: SET1A_MOUSE
Sequence: MDQEGGGDGQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDGVHFSVSDSKYTPVEDLQDPRCHVRSKARDFSLPVPKFKLDEFYIGQIPLKEVTFARLNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSVMGNIIHAQLDIKGQQRMKYYELIVNGSYTPQTVPTGGKALSEKFQGSGAAAETTEARRRSSSDTAAYPAGTTVGGTPGNGTPCSQDTNFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDSFSRRHFSTSSAPATTATATSATAAATAASSSSSSSSSSSSSSSSSSSASQFRGSDSSYPAYYESWNRYQRHTSYPPRRATREDPSGASFAENTAERFPPSYTSYLAPEPNRSTDQDYRPPASEAPPPEPPEPGGGGGGSGGGGGGGGGGGGGAPSPEREEARTPPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSAGPGARDAGAEVPSGAGHGPCTPPPAPANFEDVAPTGSGEPGAARESPKANGQNQASPCSSGEDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLTAASAGPPGGAFGEAFLPFPPPQEAAYGLPYALYTQGQEGRGSYSREAYHLPLPMAAEPLPSSSVSGEEARLPHREEAEIAESKVLPSAGTVGRVLATLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAKQQAKEEDKEKMKLKEPGMLSLVDWAKSGGITGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEREKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFTLDSEGEEASQESSSEKDEDDDDEDEEDEEQEEAVDATKKEAEASDGEDEDSDSSSQCSLYADSDGENGSTSDSESGSSSSSSSSSSSSSSSSSSESSSEEEEQSAVIPSASPPREVPEPLPAPDEKPETDGLVDSPVMPLSEKETLPTQPAGPAEEPPPSVPQPPAEPPAGPPDAAPRLDERPSSPIPLLPPPKKRRKTVSFSAAEEAPVPEPSTAAPLQAKSSGPVSRKVPRVVERTIRNLPLDHASLVKSWPEEVARGGRNRAGGRVRSTEEEEATESGTEVDLAVLADLALTPARRGLATLPTGDDSEATETSDEAERPSPLLSHILLEHNYALAIKPPPTTPAPRPLEPAPALAALFSSPADEVLEAPEVVVAEAEEPKQQLQQQHPEQEGEEEEEDEEEESESSESSSSSSSDEEGAIRRRSLRSHTRRRRPPLPPPPPPPPSFEPRSEFEQMTILYDIWNSGLDLEDMSYLRLTYERLLQQTSGADWLNDTHWVQHTITNLSTPKRKRRPQDGPREHQTGSARSEGYYPISKKEKDKYLDVCPVSARQLEGGDTQGTNRVLSERRSEQRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLEDNKIPCLCGTESCRGSLN
What is the function of this protein?
Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism.  Part of chromatin remodeling machinery, forms H3K4me1, H3K4me2 and H3K4me3 methylation marks at active chromatin sites where transcription and DNA repair take place (By similarity).  Responsible for H3K4me3 enriched promoters and transcriptional programming of inner mass stem cells and neuron progenitors during embryogenesis (PubMed:24550110, PubMed:29490266, PubMed:31197650).  Required for H3K4me1 mark at stalled replication forks.  Mediates FANCD2-dependent nucleosome remodeling and RAD51 nucleofilaments stabilization at reversed forks, protecting them from nucleolytic degradation.  Does not methylate 'Lys-4' of histone H3 if the neighboring 'Lys-9' residue is already methylated (By similarity).
What are the official names of this protein?
Histone-lysine N-methyltransferase SETD1A, SET domain-containing protein 1A.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Chromosome. Note=Localizes to a largely non- overlapping set of euchromatic nuclear speckles with SETD1B, suggesting that SETD1A and SETD1B each bind to a unique set of target genes.
Protein: Y4775_RALSO
Sequence: MEYLRIAFLFALTALAEIVGCYLPWLVLRQAKSAWLLMPAALSLALFAWLLTLHPTAAGRTYAAYGGMYIAVALAWLRVVDGATLTRWDIGGAAIALAGMAVIALQPQPT
What are the official names of this protein?
UPF0060 membrane protein RSp1275.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL28_LIMRD
Sequence: MAKDFINGKRTQFGNKRSHALNSSRRSWKPNLQKVTILVNGKPKKVYVSARTLKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: END3_RICTY
Sequence: MQAQIVNKIFEIFSKNNPKPQTALIYKNDFTLLVAVILSARATDISVNLVTKHLFETYNTPEKILALGEEGLKKYIKSIGLFNSKAKNIIASCQILIKNYQASIPNDFKELVKLPGVGRKTANVVLNCLFAMPTMAVDTHVFRVSKRIGLAKGNTTVIVEKELLQIIDEKWLTHAHHWLVLHGRYICKARKPSCRICHIKEYCEYYINTFAS
What is the function of this protein?
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity.  The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site.  The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
What are the official names of this protein?
Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: CP4E3_DROME
Sequence: MWLAVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDWWYDYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRLRERRS
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Cytochrome P450 4e3, CYPIVE3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: END4_DICDI
Sequence: MNPFVNLFIQHSKKQIFLNNNKNNILLNFNSKLYSTITYKNNNNNNNNQIINNKTIMKRKNNEIIQTEEDDDNDNGGIHDCDSCDEVDNEEIIPESPPSKKLQQQQQQQQQQQSKLKPKQTSITDFFSPTVKTSKADKISPFFSNVNNASTTNTTTNNKNVNKKTTTTTTTKKRNNKDEENEDDNEEEEEEEEEEEDKKSKKKTTTTTTTTTTTAYKKKSSPKKKKVNPTENKFSTINYKDDQYVQKEEYSSSKKEKLENVKIGGHVSIKNGYPTLIQSVVAQGFKAVAFFTNPPRTWKHHTVKLDDSIKFKQSCKSLNFDVNCILPHGSYFLNLGSPNKENLQKSRDLMIHEMKNCEILGVKHFNFHPGSHLNEISESESIKIVAESLDYILERTKDVVAVIECTAGQGTNLGYTFEHLRDMIALVKDKTRVGVCLDTCHMFAAGYNISTKSNCDVIFQEFDKVVGFKYLKGVHLNDSKSTCGSKLDRHENIGKGHIGTPCFKYLVNDKRFQNIPMILETVGPYDQEVKLLYSFIEDDDKK
What is the function of this protein?
Plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues.
What are the official names of this protein?
Endonuclease 4 homolog, Apurinic/apyrimidinic endonuclease, AP endonuclease, DdAPN, Endodeoxyribonuclease IV homolog, Endonuclease IV homolog.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AAMA1_AMAFL
Sequence: MSDINATRLPIWGIGCNPCVGDEVTALLTRGEA
What is the function of this protein?
Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters (PubMed:24613547).
What are the official names of this protein?
Alpha-amanitin proprotein.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: UBE2C_MOUSE
Sequence: MASQNRDPAAASVAAVRKGAEPCGGAARGPVGKRLQQELMILMTSGDKGISAFPESDNLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKDKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVSSQDP
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination.  Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis.  Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 C, (E3-independent) E2 ubiquitin-conjugating enzyme C, E2 ubiquitin-conjugating enzyme C, UbcH10, Ubiquitin carrier protein C, Ubiquitin-protein ligase C.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: CB2C_SOLLC
Sequence: MAAATMALSSPSFAGQAVKLSPSASEISGNGRITMRKAVAKSAPSSSPWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLVHAQSILAIWACQVVLMGAVEGYRIAGGPLGEVVDPLYPGGSFDPLGLAEDPEAFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLENLADHLADPVNNNAWAFATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein 1C, chloroplastic, LHCII type I CAB-1C, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: IOVO_DRONO
Sequence: MTMASVLVLLSLVLCCFPDTAFGVEVDCSKYPNTTNEDGKEVLLCPKILNPICGSDGVTYSNDCLLCAYNIEYGANVSKDHDGECKEAVPIDCSKYANATNEEGKEVPLCTKILSPVCGTDGVTYSNECLLCAHNIEQGTSVGKKYDGECKKEFATVDCSDYPKPVCSLEYMPLCGSDSKTYNNKCDFCNAVVESNGTLTLGHFGKC
What are the official names of this protein?
Ovomucoid, OVM.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIG_PSEAE
Sequence: MSNVDHAEIAKFEALAHRWWDRESEFKPLHDINPLRVNWIDERAGLAGKKVLDIGCGGGILSEAMAQRGASVTGIDMGEAPLAVARLHQLESGVAVDYRQITAEQMAEEMPGQFDVVTCLEMLEHVPDPASVIRACHRLVKPGGQVFLSTINRNPKAYLFAVIGAEYILQLLPRGTHDFRKFIRPSELGAWSREAGLEVKDIIGLTYNPLTKHYKLANDVDVNYMVQTKREA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: EDN2_FELCA
Sequence: MVAMPTAWCSIALALLLALHEGKGQVAAAPDQPAPSHRARASHLRPRRCSCSSWLDKECVYFCHLDIIWVNTPGQTAPYGLGNPPRRRRRSLPKRCECSSGRDPACATFCHRRPKPEAVVVPGSGPPPDVFQAGRARPSAGELLQQLRDISAAKSHFARRQQVAVRELRPTHSRRWKR
What is the function of this protein?
Endothelins are endothelium-derived vasoconstrictor peptides.
What are the official names of this protein?
Endothelin-2, ET-2, Preproendothelin-2, PPET2.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YDHE_BACSU
Sequence: MKTVLILNFPAEGHVNPTLGITKAFSDKGYDVHYISTEKYKKRLEAAGATVHLHRDLLRTTPIHVGSPNGILDFVKIHIKTSLDILQIVKDLSKSIQFDFVYYDKFGAGELVRDYLDIPGVSSSASFLFGEEHLKILPLHPESGAPLELDQECEDLLAKMKETYGVAPKNLVQFMNNKGELNVVYTSRYFQPESDRFGDECLFIGPSFPKRAEKTDFPIEQLKDEKVIYISMGTVLDHTEDFFNLCIDAFSGFNGKVVIAAGEKADLTKLKQAPENFIIAPYVPQLEVLEQSDVFITHGGMNSVNEGIHFSVPLVVMPHDKDQPMVAQRLSELHAGYVISKDEVNAQILKQAVDEVLRNDQYTAGIKKINQSFKECMDMEEVMERIDELIRQKNK
What are the official names of this protein?
Uncharacterized UDP-glucosyltransferase YdhE.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: UBIE_ECOBW
Sequence: MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: BEM1_YEAST
Sequence: MLKNFKLSKRDSNGSKGRITSADISTPSHDNGSVIKHIKTVPVRYLSSSSTPVKSQRDSSPKNRHNSKDITSPEKVIKAKYSYQAQTSKELSFMEGEFFYVSGDEKDWYKASNPSTGKEGVVPKTYFEVFDRTKPSSVNGSNSSSRKVTNDSLNMGSLYAIVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFVSIIDIATGYATGNDVIEDIKSVNLPTVQEWKSNIARYKASNISLGSVEQQQQQSITKPQNKSAKLVDGELLVKASVESFGLEDEKYWFLVCCELSNGKTRQLKRYYQDFYDLQVQLLDAFPAEAGKLRDAGGQWSKRIMPYIPGPVPYVTNSITKKRKEDLNIYVADLVNLPDYISRSEMVHSLFVVLNNGFDREFERDENQNNIKTLQENDTATFATASQTSNFASTNQDNTLTGEDLKLNKKLSDLSLSGSKQAPAQSTSGLKTTKIKFYYKDDIFALMLKGDTTYKELRSKIAPRIDTDNFKLQTKLFDGSGEEIKTDSQVSNIIQAKLKISVHDI
What is the function of this protein?
Necessary for cell polarization during vegetative growth.  May link the cytoskeleton to morphogenic determinants on the cell surface.
What are the official names of this protein?
Bud emergence protein 1, Suppressor of RHO3 protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYK_STRPG
Sequence: MSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFDRTANSAELKEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVSEDNYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETIYRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFVTHHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVDFWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVSPLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATGIDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.