PharMolix/UniProtQA huggingface dataset:
Protein: PEX3_DICDI
Sequence: MENFQFEDLSPNKVSKVYQDLKKFGSFLYNHKMGVFLVSFSSGVAYLYHNITQSHKRKQIKLAKERVMTYFESTQKLSEREVDAIITKFIDENKILDKIQTPSLASIRSEKDPSEKLKLTDQLKVSIITKLFSVLYIIPMVTIFNRLQINLIGKYCYLDYVLYKDQEQHSMRLINQQTESNFINSRNNCYFFKDINFSQFINLIQEQIKISLKDWKIDQQSSFEGFLKLLINIRNNFEKKEIIASISSDNSLLKYLIPTEEEIDNLVQSQKTPENDNDIEYQNLKMLYNEIRNIFESQKFYDVLKDSINQSFLEFTKNLREDFESTELKKQIDSIVLPDLPIEMEIPKPLVTMHNIILLPKINKQIGNIIVNKKSIIEKIGSTDLINQLNYSVLTNDLDFNKVQF
What is the function of this protein?
Involved in peroxisome biosynthesis.
What are the official names of this protein?
Peroxisome biogenesis factor 3, Peroxin-3.
What is the protein family that this protein belongs to?
Belongs to the peroxin-3 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: VATO2_ARATH
Sequence: MSGVAIHASSWGAALVRISPYTFSAIGIAISIGVSVLGAAWGIYITGSSLIGAAIEAPRITSKNLISVIFCEAVAIYGVIVAIILQTKLESVPSSKMYDAESLRAGYAIFASGIIVGFANLVCGLCVGIIGSSCALSDAQNSTLFVKILVIEIFGSALGLFGVIVGIIMSAQATWPTK
What is the function of this protein?
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit c''2, V-ATPase subunit c''2, Vacuolar H(+)-ATPase subunit c'' isoform 2, Vacuolar proton pump subunit c''2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PAFB_MYCTO
Sequence: MATSKVERLVNLVIALLSTRGYITAEKIRSSVAGYSDSPSVEAFSRMFERDKNELRDLGIPLEVGRVSALEPTEGYRINRDAYALSPVELTPDEAAAVAVATQLWESPELITATQGALLKLRAAGVDVDPLDTGAPVAIASAAAVSGLRGSEDVLGILLSAIDSGQVVQFSHRSSRAEPYTVRTVEPWGVVTEKGRWYLVGHDRDRDATRVFRLSRIGAQVTPIGPAGATTVPAGVDLRSIVAQKVTEVPTGEQATVWVAEGRATALRRAGRSAGPRQLGGRDGEVIELEIRSSDRLAREITGYGADAIVLQPGSLRDDVLARLRAQAGALA
What is the function of this protein?
Part of the pafABC operon, however PafB does not seem to be involved in pupylation or substrate degradation.
What are the official names of this protein?
Protein PafB, Proteasome accessory factor B.
What is the protein family that this protein belongs to?
Belongs to the PafB family.
Protein: CHEB_ALKEH
Sequence: MKVRALVVDDSGFFRRRIKSMLEEHPGIEVVGEAANGRQAVEQAQKLRPDVITMDIEMPEMDGITAVREIMRRQPTPVLMFSSLTYDGARETLDALDAGASDFIPKRFADISGDMEQVKRQLQERVLALGGGRGAPAGRAPRPAAPVDRGARSERARPAPGEASGRAPVPPTGARARPEAPVAPTGAPAAPAPERGQRIRPGALRLVVIGTSTGGPVALQRVMSRLPAGFPLPVLIIQHMPASFTPAFAERLNELCRIEVREAKNGDELRPGQALLAPGGRQAGVEERGGKLTVRIFDASSDQFYKPSVDIAFASAAKYCPGKALGVVLTGMGADGCEGAKLLKRTGAPIWSQDEATSVIYGMPAAVAKAGVTDRVLPLDQVGEELAKLR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOX4_RAT
Sequence: MALSWRSWLANEGVKHLCLLVWLSLNVLLFWKTFLLYNQGPEYYYIHQMLGLGLCLSRASASVLNLNCSLILLPMCRTVLAYLRGSQKVPSRRTRRLLDKSKTLHITCGITICIFSGVHVAAHLVNALNFSVNYSEHFLALNAARYQNEDPRKLLFTTVPGLTGVCMVVVLFLMVTASTYAIRVSNYDIFWYTHNLFFVFYMLLLLHVSGGLLKYQTNLDTHPPGCISLNRTPSQNMSIADYVSEHFHGSLPGGFSKLEDHYQKTLVKICLEEPKFQAHFPQTWIWISGPLCLYCAERLYRCIRSNKPVTIISVINHPSDVMELRMIKENFKARPGQYIILHCPSVSALENHPFTLTMCPTETKATFGVHFKVVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILNTLLDDWKPYKLRRLYFIWVCRDIQSFQWFADLLYVLHNKFWQENRPDFVNIQLYLSQTDGIQKIIGEKYHTLNSRLFIGRPRWKLLFDEIAKCNRGKTVGVFCCGPSSISKTLHNLSNRNNSYGTKFEYNKESFS
What is the function of this protein?
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox.  Regulates signaling cascades probably through phosphatases inhibition.  May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity.  May regulate insulin signaling cascade.  May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
What are the official names of this protein?
NADPH oxidase 4, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell junction, focal adhesion. Note=May localize to plasma membrane and focal adhesions.
Protein: CM35_CONMR
Sequence: MSKLGVLLTICLLLFPLTALPLDGDQPADQRAERTQAEKHSLPDPRMGCCPFPCKTSCTTLCCG
What are the official names of this protein?
Conotoxin Mr3.5.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AROC_BURM1
Sequence: MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMALTEADIQAELDRRKPGTSRHVTQRQEADEVEILSGVFEGVTTGTPIALLIRNTDQRSKDYGNIVETFRPGHADYTYWQKYGVRDYRGGGRSSARLTAPIVGAGAVAKKWLRERFGVEVRGYMSALGEIDVPFVDWSHVRENPFFAPNAAIVPELEAYMDALRKDGDSIGARIDVVASGVPVGWGEPVFDRLDADIAKAMMSINAVKGVEIGAGFDSVAQRGSVHGDELTPAGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITKDGQPATVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVETQTPKIAGSAT
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RL14_STRAW
Sequence: MIQQESRLRVADNTGAKEILCIRVLGGSGRRYAGIGDVIVATVKDAIPGGNVKKGDVVKAVIVRTVKERRRPDGSYIRFDENAAVILKNDGDPRGTRIFGPVGRELREKKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: KEX1_UNCRE
Sequence: MSSCQPPPFLSSMVVRWLSVWIILASSAFASAKCAADYYVRSLPGQPEGPLLKMHAGHIEVDHENNGNLFFWHFQNRHIANRQRTVIWLNGGPGCSSMDGAMMEVGPYRLKDDHTLKYNEGSWDEFANLLFVDQPVGTGYSYANTNSYLHELDEMAAHFVTFMERWFELFPEYEHDDLYFAGESYAGQYIPYIAKAILDRNKNETVIAQRRLWHLKGLLIGNGWFSPVEQYLSYLPYVYKEGMVKNDSDEAKGIERAHSDCVAELDRAKGDVKIHVDVCEKILSAILDVSNKSGHCVNMYDVRLTDTFPSCGMNWPPDLKHLAPYLRRDDVTSALHINKDKKTGWTECAGAVSSSFRPRKSKPSADLLPGLLESGVRIGLFSGAKDLICNHIGTEEFINKMEWSGGKGFELSPGVWAPRRDWTFEGETAGYYQEARNLTYVLFYNASHMVPFDYARRSRDMLDRFLGVDITSIGGNPTDSRIDGEKGALTSVGNHPNSTLAEQREKEKLKAATWKAYYKSGEVALVVVVIAAGAWGFFLWRSRRQRQGSGYLGIYPSLNGLSSGSLPRYRNKRSSRDIEAAAEFEASELETLHDMDDRSPGPSRDNYSVGEDSETEDEKRYPPTDFDRQDGTPSASRT
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: CSPG2_MACNE
Sequence: YPIRAPRVGCYGDMMGKAGVRTYGFRSPQETYDVYCYVDHLDGDVFHLTAPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAASGTISTNFPQTMEPAKLWSRQEVNPERQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETELKTTGYSVLTTKKTYSDDKEMEEEGTSLANMSTPVPDANGVESFTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKEEESTKHFPKGMRPTIQELDTELLFSGLGSGEEVLPTLPTKSVNFTEVEQIRNTFYPHTSQVESTSSDKLEDFNRMENVAKEVGPLGSQTDIFEGNESVTSTTLIEILSDPGAEGPTVAPLPFFANIGHPQNQTLRWAEEIQTSKLEPSEEDGKPELLEETEASPTEFIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTVITTANEIKLEGATQWPHSTSASATYGIEAGVMPWLSPQTSERPTLSSSPEINPETQAALIRGQDSTVAASEQQVTARILDTNDQATVSPVEFNTEVATPPFSLLETSNETDFLIGINEESVEGTAIYLPGPDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCADGFNTFRCLCLPSYVGALCEQDIETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMF
What is the function of this protein?
May play a role in intercellular signaling and in connecting cells with the extracellular matrix.  May take part in the regulation of cell motility, growth and differentiation.  Binds hyaluronan.
What are the official names of this protein?
Versican core protein, Chondroitin sulfate proteoglycan core protein 2, Chondroitin sulfate proteoglycan 2, Large fibroblast proteoglycan.
What is the protein family that this protein belongs to?
Belongs to the aggrecan/versican proteoglycan family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Cell projection, cilium, photoreceptor outer segment. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.
Protein: SYI_SHEWM
Sequence: MSDYKSTLNLPETEFPMRGNLANREPVMLKSWAEDDLYQQIRDSRIGRKPFILHDGPPYANGSIHIGHSVNKILKDIIVKSKTMSGFDAPYIPGWDCHGLPIELKVEQKVGKPGHKVTAAEFRVKCREYAAKQVDGQRDDFMRLGVFGDWHNPYLTMDYSTEANIVRSLSKVIDSGHLHKGVKPVHWCTECGSALAEAEVEYEDKKSPAIDVAFAAADKVTLLAKFGVEECSGSVSMVIWTTTPWTLPANRALSVAGDIEYALVEFVKGDKTSSVILAETLVESCMERYGVDSHNVLGKTSGQSLELLRFNHPFYDFDVPVILGEHVTVDSGTGVVHTAPGHGQDDFVVGQKYGLEVANPVGDNGVYKSDTEIFAGQHVFKANDNVVALLEEKGALIKLENILHSYPHCWRHKTPIIFRATPQWFISMEQKGLRKQALNEIEQTQWIPDWGQSRIEKMVENRPDWCISRQRTWGVPIALFVHRETEELHPDSSSLMERVANKIEQEGIQAWWDLDAAELLGEEADQYRKVTDTLDVWYDSGSSFSSVVASRPEFQGHDIDLYLEGSDQHRGWFMSSLMISTAMNGKAPYKQVLTHGFTVDGNGRKMSKSVGNVIAPQTVTNKLGADILRLWVAATDYSGEMTVSDEILKRSADAYRRIRNTARFLLANINGFNPETDLVAVEEMVALDRWAVRRAAALQEELLEAYEQYNFHVVTQKLMQFCSVELGSFYLDIIKDRQYTAKGDSHARRSCQSALYLISEAMVRWIAPILSFTADEVWQLLPGQRDKYVFTQEWFQGLKSVTLESDLSDDFWSELLTVRGEVNKVIEQARREKQVGGSLEAEITLYADDALSTALATLGDELRFVLLTSKTQILDLSAAPADAIETELSSLKLGLKKAETEKCERCWHHREDVGQVATHPTLCTRCVTNIEGDGEVRQFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYADM_PONAB
Sequence: MPVTVTRTTITTTTTSSSGQGSPTIVGSPRALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGPMGNWSMFTWCFCFSVTLIILIVELCGLQARFPLSWRNFPITFACYAALFCLSASIIYPTTYVQFLSHGRSRDHAIAATFFSCIACVAYATEVAWTRARPGEITGYMATVPGLLKVLETFVACIIFAFISDTYLYQHQPALEWCVAVYAICFILAAIAILLNLGECTNVLPIPFPSFLSGLALLSVLLYATALVLWPLYQFDEKYGGQPRRSRDVSCSRSHAYYVCGWDRRLAVAILTAINLLAYVADLVHSAHLVFVKV
What are the official names of this protein?
Myeloid-associated differentiation marker.
What is the protein family that this protein belongs to?
Belongs to the MAL family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FTSZ1_PYRHO
Sequence: MLKLVENVVERVSSEETKVQEVQVPQSSIDEELKKIVEQIKARIHVVGVGGAGCNTVNRMMEVGVTGAKIIAVNTDAQDLLKVKAHQKILIGKEITRGLGAGNDPKIGEEAAKESEREIREALEGADMVFVTCGLGGGTGTGAAPVIAEMARKMGALTVSVVTLPFTMEGIRRAKNAEYGLKRLAKASDTVIVIPNDKLLEVAPKLPIQMAFKVADEILVQAVKGITELITKPGLVNLDFNDVRAVMKDGGVAMIGIGESDSEKRALEAAEQALNSPLLDVDISGAKGALISISGADVKLEEAQQIIEYVTRNVDPKAQVIWGIQLEPELEKTIRVMVIVTGITSRYVTFQEETPAPSEEETTPVKIDIPEL
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ 1.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: OCE2_LEPLD
Sequence: GVVDILKGAAKDLAGHLATKVMDKL
What is the function of this protein?
Shows a low activity in stimulating insulin release from rat BRIN-BD11 beta cells, and acts without loss of integrity of the plasma membrane (PubMed:19428765).  Does not show antibacterial (E. coli and S. aureus) (PubMed:19428765).  Does not show hemolytic activity against human erythrocytes (PubMed:19428765).
What are the official names of this protein?
Ocellatin-L2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ocellatin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVC_ACISJ
Sequence: MKVFYDKDCDLSLIKGKTVAIIGYGSQGHAHAQNLNDSGVKVVVGLRKGGASWDKVGKAGLTVKEVNDAVKEADVVMILLPDEQIAEVYKNNVEPHIKQGASLAFAHGFNVHYNQVVPRADLDVWMVAPKAPGHTVRNTYTQGGGVPHLVAVHQDKSGKARDLALSYAMANGGGKAGIIETNFKEETETDLFGEQAVLCGGAVELIKMGYETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEFGEYVTGPEVINEQSRAAMRNALKRIQNGDYAKMFIQEGRLNYPSMTARRRNTADHSIEVVGAQLRAMMPWIAKNKLVDQTRN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YCBX_ECOLI
Sequence: MATLIRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGTFITARQFPQMVRFTPSPVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIAPDAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQRCPASVKMEQFRPNLVVSGASAWEEDRWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQKHPAGEPLKTLQSFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAAADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQLLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLAR
What are the official names of this protein?
Uncharacterized protein YcbX.
Protein: ADD_PECAS
Sequence: MIDLRLPLTDIHRHLDGNIRAQSILELGRQYNIALPASDLDALRPHVQVTKNEPDLLSFLQKLDWGVAVLGSLDACRRVAYENVEDAMNAGLDYAELRFSPYYMAMNHKLPIAGVVEAVIDGITAGSRDFDTDIRLIGIMSRTFGTEACQQELDALLSQRDRIVALDLAGDELGYPGAQFTSHFQQARDAGWHITVHAGEAAGPESIWQAINHLGAERIGHGVTAIIDPRLMTHMAETGIGIESCLTSNIQTSTVETLDKHPLIHFLRYGIPATINTDDPAVQGIEIRHEYEVAAPLAGLTAVETRKAQENGLNIAFISEQEKQQLREKVLRKRASA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: GLMM_RHOPT
Sequence: MSRRYFGTDGIRGRANGLITPELALKVGQAAGLAFQRGEHRHRVVIGKDTRLSGYMIENALVAGFTSVGMDVLLVGPMPTPAVAMLTKSMRADLGVMISASHNLFEDNGIKLFGPLGYKLSDDVEKQIELMLDESLDKKLAQSASLGRARRIDGVHDRYIEFAKRTLPRELSLEGLRVVIDCANGAAYKVVPEALWELGADVISIGVEPDGFNINKECGSTAPQALCAKVREMRADIGIALDGDADRVILVDERGHVVDGDQLLAVIGQSWKEDGRLAKPGVVATVMSNLGLERFLAGEGIALLRTPVGDRYVLEQMLKDGYNVGGESSGHIILSDFNTTGDGFVAALQVLAMVQKLGRPVSEVCRRFDPLPQILKNVRYRSGRPLDDSGVISAIQDGEKRLNGHGRLLIRPSGTEPVIRVMGEGDDRDVVEEVVDSIVDALGNAAAAAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RNFE_SHELP
Sequence: MSNYRDIAWQGLWKNNPGLVQLLGLCPLLAVTATLTNAIGLGLATLVVLVGSNVLVSLVREFVPKEIRIPVFVMIIAALVTCVQLLINAYAYGLYLSLGIFLPLIVTNCVIIGRAEAFASRNSVVKAAFDGLMMGLGFTLVLMLLGACREILGQGTLFDGADLLLGDWAKGLTIHLWQVDTNFLLAMLPPGAFIAMGFLIAIKNMIDKQLEARKPALEAAPAVTRARITKVS
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KDPB_ECOL6
Sequence: MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGVMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKKTAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVEEKALADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVEANGGHFPADVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SKI11_MOUSE
Sequence: MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH
What is the function of this protein?
May act by engaging a cell surface molecule on immature T-cells in the embryonic thymus.
What are the official names of this protein?
Selection and upkeep of intraepithelial T-cells protein 11, Skint-11.
What is the protein family that this protein belongs to?
Belongs to the SKINT family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CCTM_TALIS
Sequence: MEPGTDVRRVLVIGAGAAGLLIAQVLKKHGVPCTVFEQDTKADARPRDWNYGIYWAQSYLAECLPPELVSQLESAQVDSHTPSGSDILPTFNLATGEPLISVSAPYSYRLQRRKFLNLISTGIDIQYGKRLTMVDSDNKTVTAVFEDSSQATGNLLIGTEGAHSRVREYLLGKERAAVIPSRIVASATVSRLPEREVSALRKLHPRYCIAIHPDGYFNWLGIHDEAAQSKDCTFMIILSWISESDTGLSGTAIAADLKERANTFGEPFRTVLQSIPSETTFWHNRLSSWPTQPWNSHNGTVTLAGDAAHPMTFHRGQGLNNAITDAAYFGRQLAALDTKSTESLSAVVTAFEEELWKRGNEAVTQSDINSLSVHNWEELKSSPLFTSGLKQRSST
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of the mycotoxin cyclochlorotine, a hepatotoxic and carcinogenic cyclic chlorinated pentapeptide (PubMed:26954535).  Cyclochlorotine is formed by the nonproteinogenic amino acids L-2-aminobutyrate (2Abu), L-beta-phenylalanine (beta-Phe), the unique L-cis-3,4-dichloroproline Pro(Cl(2)) and two L-serines (Ser) (PubMed:26954535).  The condensation of the 5 building blocks is performed by the cyclochlorotine synthetase cctN, a nonribosomal peptide synthetase (PubMed:26954535).  The assembled linear pentapeptide is then assumed to be released through cyclization by the terminal condensation-like domain of cctN (PubMed:26954535).  Incorporation of the alternative substrates allo-threonine or alanine by the domains A3 or A1 respectively may lead to the production of the variants hydroxy-cyclochlorotine and deoxy-cyclochlorotine, respectively (PubMed:26954535).  CctP probably acts as a phenylalanine aminomutase and provides the uncommon building block beta-Phe (PubMed:26954535).  Furthermore, 2Abu can be synthesized from threonine by one of the threonine dehydratases and transaminases localized outside of the cluster (PubMed:26954535).  The biosynthesis of the unusual dichloroproline moiety remains elusive since the actual halogenase still awaits to be detected, with the possibility that proline halogenation is accomplished by a so far unknown type of halogenase (PubMed:26954535).  Finally, the cluster encoded transporters cctQ and cctS are most likely responsible for cyclochlorotine secretion and thereby may contribute to intrinsic resistance (PubMed:26954535).  The functions of the remaining proteins encoded by the cluster (cctM, cctO, cctR and cctG) have not been identified yet (PubMed:26954535).
What are the official names of this protein?
FAD-dependent monooxygenase cctM, Cyclochlorotine biosynthesis protein M.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: DAPD_PSYCK
Sequence: MSLQQTIEQAFENRNEYSPATMPQDVRDAINQVLEQLDNGTLRVAEKKDGEWVVNQWAKKAVLLSFRLNDNYVQAAGEHVQFYDKVPTKFANWTEAQFKEAGVRVVPPAVARKGSYIAPGAVLMPSYVNIGAYVDQGAMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGAVISMGVYIGQSTRIYDRETGEIHRGRVPAGSVVVPGSLPSEDGTHSLYAAIIVKKVDAQTRAKTSVNELLRLA
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_FRATN
Sequence: MAKYFGTDGIRGEVANSTITAEFTQKLGNAVGSLINQKNYPKFVIVGQDTRSSGGFLKFALVSGLNAAGIDVLDLGVVPTPVVAFMTVKHRAAAGFVITASHNKFTDNGIKLFSSNGFKLDDALEEEVEDMIDGDFIYQPQFKFGSYKILANAIDEYIESIHSRFAKFVNYKGKVVVDCAHGAASHNFEALLDKFGIDYVSIASNPDGLNINVGCGATCISNIKKAVKEQKADLGISLDGDADRIIIVDENGQEIDGDGILNILAQYSDICGGTNGIVGTQMTNMSYENHYRANKIPFIRSKVGDRYVLEDLVKYGYKIGGESSGHVINLNFGTTGDGLFTAIQLLAIFSQADKPVSEFKLQGELMQQTLINVPLAKKVTREDLQKVASDVNDVEKRLGNRGRVLLRPSGTEPVLRVMVEADDKSLATNEAEYLVEKVKQKLV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.