PharMolix/UniProtQA huggingface dataset:
Protein: LIGB_SALAR
Sequence: MGVWKSMVWGVLLWHSQSGAICPVWPSARTIEEIARLQQQLADWNDIYWKQGVSAVDDSVYDQLSAKLVQWQRCVGQDVSSTPVSPPLNGTTTHPVAHTGVRKLADRQAVAQWMRGHSEFWVQPKVDGVAVTLVYQNGKLTRAISRGNGLQGEDWTQKIRQISSIPQTTRGALANAVLQGEIFLQLKGHIQQRMGGMNARSKVAGMLMRQKNTSALNSLGIFIWAWPDGPANMTERLSQLAKAGFSLTQKYSQMVKNASEVERARRSWLTSALPFVTDGVVIRMAKEPSSQYWRPGQGDWLAAWKYPPVAQVAQVSAIQFSVGKSGKISVIASLVPVMLDDKRVKRVNIGSVKRWEAWDIAPGDQILVSLAGQGIPRLDEVVWRSRERSKPVPPGNHFNSLTCFYASATCQEQFISRLVWLGSRAALGLDGMGEASWRALHQTHRFEHIFSWLALTPAEIANTPGFAKGKSELIWRQFNLARRQPFSRWVMAMDIPLTQAALQASGDRSWEQLLMRTDQHWRQLPATGERRAGRVSDWRDNPRIKALSRWLAAQHIPGFGT
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: G6PI_YERPB
Sequence: MKNINPSQTAAWKALQQHFEQMKDVTISSLFAKDDQRFNRFSATFDDQMLVDFSKNRITSETLEKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHIALRNRSNTPIVVDGKDVMPEVNAVLAKMKQFCDRVISGDWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEALKPLNPETTLFLVASKTFTTQETMTNAHSARDWFLSAAGDPAHVAKHFAALSTNAKAVGEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSVGFEHFEQLLSGAHAMDKHFAETPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFPAYFQQGNMESNGKYVDRNGHPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAISHNPLSDHHAKLLSNFFAQTEALAFGKSLEDVEAEFAAAGKTPEQVAHVAPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIYTFDQWGVELGKQLANRILPELADDQEVTSHDSSTNALINRFKNWR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYR15_ECOLX
Sequence: MKLSLMAAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVGRKTFESMGALPNRKYAVVTRSSFTSSDENVLVFPSIDEALNHLKTITDHVIVSGGGEIYKSLIDKVDTLHISTIDIEPEGDVYFPEIPSSFRPVFSQDFVSNINYSYQIWQKG
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase type 15, Dihydrofolate reductase type XV.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: AGD9_ARATH
Sequence: MATENLTDKNVVFRKLKSKSENKVCFDCSAKNPTWASVPYGIFLCIDCSAVHRSLGVHISFVRSTNLDSWSPEQLRTMMFGGNNRAQVFFKQHGWNDGGKIEAKYTSRAADMYRQTLAKEVAKAMAEETVLPSLSSVATSQPVESSENGFTSESPKESSLKQEAAVVSSPKASQKVVASTFKKPLVSRKSGKTGGLGARKLTTKSKDNLYEQKPEEPVPVIPAASPTNDTSAAGSSFASRFEYFDDEQSGGQSGTRVLSHVAPPKSSNFFNEFGMDSAFPKKSSSSSSKAQVEETDEARKKFSNAKSISSAQFFGNQNRDADLDSKATLQKFSGSAAISSSDLFGHGPDDSNIDITASDLINRISFQAQQDMSSIANLAEETKNKLGTFASSIFSDLQDRML
What is the function of this protein?
GTPase-activating protein (GAP) for ADP ribosylation factor (ARF).
What are the official names of this protein?
Probable ADP-ribosylation factor GTPase-activating protein AGD9, ARF GAP AGD9, Protein ARF-GAP DOMAIN 9, AtAGD9.
Protein: F16PA_LEPBA
Sequence: MNATPKQKKLISLSQFILEEQLKIPHASGEFSALLSHLVYAAKIVGREVRKAGLLDDILGATEDTNVQGETQMKLDQYADNAFNQSLKICGHLCVLASEEHEDIIPIPGGYNIGKYTMAIDPLDGSSNIDTNVSIGTIFSIHQRLEPNSKEPGNERDLLQKGHLQRCAGYIIYGSSTMLVLSTGKGVSGFTLDPSVGEFLLSHPNMQMPESGDIYSANEGNASYWSPEVQAYLQKIKSIEGGKKPKTARYIGSLVADFHRNLLKGGIFLYPNDTKSSKYPNGKLRLLYEAAPMAFIAEQAGGMAVTVKGERILDLTPKDLHERTTLIIGSKKEVEEFLTFVAK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y074_SIFVH
Sequence: MNYFSVIMYLINSVIFTFMIFLTFVNPSLLNDQYWVYILIGFFTAIVFHSGYQAGKGSEK
What are the official names of this protein?
Putative transmembrane protein 74.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: RL6_XYLF2
Sequence: MSRVAKKPISIPKGVEVSVQSDMLTVKGVKGVLTFPKSDNVNVVMDGDILTLSANDHSHVSLAGTVRAILSNMIKGVSIGFERKLELVGVGYRASMQGKDLNLSLGFSHPLLFVPPEGINLLTPSQTEVVVQGIDKQRVGEVAAKIRNFRPPEPYKGKGLKYATEAIMRKEAKKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL31_MYCVP
Sequence: MKSGIHPDYVETTVLCGCGASFTTRSTKQSGQITVEVCSQCHPFYTGKQKILDSGGRVARFEKRYGKRKTTADK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ATPF2_GRATL
Sequence: MIVFPFLLFQMLSTEVEGGLFDFNATLPLMALQFIILTTILNFIFYKPVTNVLDERDEYIRNSLTTASASLVKADELTKTYEQQLAESRKKAQDIIKVAQEQAQQIVSVKIKDAQAYGEKLVSEAFHQLSIQKEDALKTLEMQVDTLSDLIKSKLLND
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', chloroplastic, ATP synthase F(0) sector subunit b', ATPase subunit II.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RAB9A_CANLF
Sequence: MAGKSSLFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISERQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLATEDRSDHLIQTDTVSLHRKPKPSSSCC
What is the function of this protein?
Involved in the transport of proteins between the endosomes and the trans-Golgi network (PubMed:8440258).  Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).
What are the official names of this protein?
Ras-related protein Rab-9A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle membrane. Melanosome. Note=Colocalizes with OSBPL1A at the late endosome. Recruited to phagosomes containing S.aureus or M.tuberculosis.
Protein: YCIC_ECOL5
Sequence: MSITAQSVYRDTGNFFRNQFMTILLVSLLCAFITVVLGHVFSPSDAQLAQLNDGVPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVILIIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLALAPVMLVQDKMGVFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEIGAVLANTLSNLISAVLLIYLFRLYMLIRQ
What are the official names of this protein?
UPF0259 membrane protein YciC.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPE_WOLPM
Sequence: MNTFKVQFFSPDDQISFSGVVSLSVTGLEGELMILAHHAPYLIYLLPGMITVKMSNQTEKKVVIDSGVLEVANNNCSIITSQIQVFDRAIHDEKSFKNKRISIYLSYLDEKFLS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NDK_TREPA
Sequence: MAFETTFVMLKPGVLQRRLVGEVLSRFERKGLVLTALRLLCVDTATAELHYAEHREKPFYPSLIAYITSAPVVALAFKGENAISLVRTLCGSTRVEHAQPGTIRGDFALRTTTNIVHASDSPESAARELALYFSAQDFVEWRDGNYDFF
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSEP_GLOMM
Sequence: MKFFISFAFLCLVLSCVAALSPDQVESRLKSYVENRSFALLRSGRVARAGTNTVQCYDKYVPLIRQAAAEGKFASDKCAQEGQNAREEETKKSEVIRESLNVKVASIEKGLGACVAKYDVLEYFTCLRDHASESQTAAGEVGKTSAVIVEGLNIVLTNIELREKYCIDQAFEQAQEKSDILFTELENCLIEGLPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPQPEPESKPNSLFNF
What are the official names of this protein?
Protein TsetseEP, EP-repeat protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RL6_STRP2
Sequence: MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIRVEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSKLVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGKGIRYVGEFVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TRUD_HAEI8
Sequence: MLEQLPYLALKTPPKTTALLKAECADFIVKEHLGYEMSGDGEFVALYVRKTDCNTLFVGEKLAKFAGVSERNMGYAGLKDRRAVTEQWFCLQMPGMETPDFSQFELDGVEILTVTRHNRKIRTGSLEGNYFDILLRGAEESDELKVRLDFVANFGFPNYFTEQRFGREGHNLTQALRWAQGEIKVKDRKKRSFYLSAARSEIFNLVVAARIAKGATNQVLPNDIVQLAGSHSWFKADEKEDLTVLQVRLENQDILLTAPLIGEDILAASDIENEIVNQHSAFDSLMKQERMKAVRRPLLMKAKGFSWAFEPEGLRLKFYLPAGSYATALVRELVNYTEE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: MBR1_ARATH
Sequence: MNPMQGPRSIGGSSTEVNQVDGESIYCTETSLNTMLNPADTGFPNNSTPSGRPTYASSSSHAAQDHTWWRFGESSSIPGPSDQVNSIGIKTSHQLPQDGTHHFVGYGSEGRQTGLNGMMVDGGVHAGSHIRNVPSFLRGSSSNPMPQHVDMSMDMDSDNCNAQTSGVVIRHNSYGSSLGSSVQAAGESSSGPASPFGGWGSSCKRKALEGSPSHYFSGETPNRIVQTENSASHASLSQYGASSSLSLATPSQSSPNVTNHFGRTEQMFGSGGGRAVAASAFHSTRNTDTLSRAGRRLNPRQPQESVAFSVSHGGTSVRPTGSLQQNLPLNSPFVDPPDVRSSSITSGSNTGENQTNIVHLPALTRNIHQYAWDASFSSRASNPSGIGMPAERLGPQWETPRSNQEQPLFAPATDMRQPVHDLWNFARGSPGSSVDSLFVPRAGPSSAIHTPQPNPTWIPPQNAPPHNPSRTSELSPWSLFPSIESPSASHGGPLPLLPAGPSVSSNEVTMPSSSNSRSHRSRHRRSGLLLERQNELLHLRHIGRSLAADGNGRNQIISEIRQVLHAMRRGENLRVEDYMVFDPLIYQGMTDMHDRHREMRLDVDNMSYEELLALGERIGDVSTGLSEEVILKAMKQHKHTSSSPSSVELHQNIEPCCICQEEYVEGDNLGTLKCGHEFHKDCIKQWVMIKNLCPICKTEALKTP
What is the function of this protein?
E3 ubiquitin-protein ligase that functions as regulator of MED25 stability by targeting MED25 for degradation in a RING-H2-dependent way.  Proteasome-dependent degradation of MED25 seems to activate its function as positive regulator of FLOWERING LOCUS T (FT) and is important to induce the expression of FT and consequently to promote flowering.
What are the official names of this protein?
E3 ubiquitin-protein ligase MBR1, MED25-binding RING-H2 protein 1, RING-H2 finger MBR1, RING-type E3 ubiquitin transferase MBR1.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family.
Protein: NADK_SALHS
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_RHOPA
Sequence: MAMNQEIMNLFNPTTPAQVFDQIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCSVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGQLLDMTLKDLERILYFEYYVVLEPGLTDLKERQLLSEEEYLRAQDQYGQDSFTAMIGAEAIRELLKGLELEKIDAQLRAEMAETDSDIKHKKLAKRLKIVEAFRYSGNKPEWMILTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYSRLDAKGLSTTVKQAKKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSIMREGLPGEGKVFADLAELEHALYSKVIHLHTKIKYRWHWVNEEGENTVRLLETTAGRILLGQVLPKSPKLPFDVINKLMTKREISGVIDQVYRHCGQKETVIFCDRIMALGFFNAFKAGISFGKDDMVVPGSKWKIVDSTRTLAKDFEQQYNDGLITHGEKYNKVVDAWSKATEEIAKEMMKEISAVRKAPDGSEQQVNSIYMMAHSGARGSPAQMRQLAGMRGLMAKPSGEIIETPIISNFKEGLSVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIITQADCGTSLGIKMRAIVDAGTVVASLGSRILGRTAGEDVRDPATNEIIVKRGDLMEERDVEAIHQAGVQEVKIRSALTCELVNGICGKCYGRDLARGTPVNHGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQINEQSVIESNFDGKIVIKNRAIARNGEGHNVAMVRNMVIAIVDPDGTERATHRIQYGARVHVDEGDMVKRGQRIAEWDPYTRPILTEVEGEIGFEDLIEDQSISETLDESTGIAKRIVIDWRSTRGGADLRPAIVIKGKDGKVLKLARGGDARYMLSVDAILSVDVGAQVKPGDILARISTESAKTRDITGGLPRVAELFEARRPKDAAIIAEIAGTIRFGRDYKNKRRLSIEPLDKNEEAREYLIPKGKHIHLQDGDVVEKGDFIVEGNPAPHDILAIKGIEELAAYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKIEITDQGDTDMISGEQVDKIEFNALNAKAVEEGKKPATGNPVLLGITKASLQTRSFFSAASFQETTRVLTEAAVNGKVDPLEGLKENVIVGRLIPAGTGASMAKIREVAVKRDRLILDEREKQAAIVPAAAPEAEPLSLPPAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RS19_SINFN
Sequence: MARSVWKGPFVDGYLLKKAEKVREGGRNEVIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSEEMVGHKFGEFAPTRTYYGHGADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SSH4_CANGA
Sequence: MPLIPDSIQSIGVFHVDDPFNPMPDPGDADPETVAFAFFIGIAVVFSLLLITLVCTAAYLVCTSSYEGEYDEELANNGDGSRRGILNFRPLFGKKNSNGLLLDSNFTNPGEFDDNEEFIEREREALIKMSPFEVDSYMRAKEFQIVSPPAVQEFGTYLDSKDLQMIKDRGIQSYYFIPSINDNVDKSGHFLPSFLVQDKLEVEFTRWNKSSSAVLNYPLPYNKKDAVYFEVKVYNHKPNSNSIFSIGLVTVPYPYFRIPGMCKFSIAYESTGKLRINDPFFPSTLLPKLVEGDVVGFGYRFKTGTIFITHNGKKLMDVTQNVSVELFIALGAMNASYTRTYTKDGLLEDPDNIELRNALAEGRELKLSKDIQNPHNPMDETKWDIIDSDEIELHVNLGQTGFVFIEANVKKYGFGSVFGEIGIPPAYNPNDIQKDKLIQKGEELPPQYPEDTENFGLFGNLKIKSHIKNPLKEVSSNPSAPELIQKKLKTPIVKTPKVGIYEFTTPIDRKRETNMQPSINPPVYEINDTRQSSPEITNETISNEETVSSSSKAEPALQHGQSNKTPNKRQNKKTKQRKNKKKGKKNK
What is the function of this protein?
Components of the endosome-vacuole trafficking pathway that regulates nutrient transport.  May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity).
What are the official names of this protein?
Protein SSH4.
What is the protein family that this protein belongs to?
Belongs to the SSH4 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Protein: RRP3_PHANO
Sequence: MSDFKRRKLEGGKSAIDAARERKALKKASAPLKKSHAKPAPSNKPTAKRPPPPSPPQSQSEEDEDEFGGFSGEEEEDVSRAKMTNGSTAKADAEAEQSDEEAEAQAAAAVEAPKKTFADLGVREELCDACENLGYKTATPIQTESIPLALAGKDIIGLAETGSGKTAAFVLPILQALLDKPQAYFGLIMAPTRELAYQISQQVDALGSIINVKCATLVGGMDMVPQAIALSKRPHIIVASPGRLLDHLENTKGFSLKHLKYLVLDEADRLLDLDFGDSLDKIFKVLPRDDRHTYLFSATMSSKVESLQRAALKNPVRVSISSSSHQVVSTLLQSYMLIPHKYKDLYLIHLLNDNIGHATILFTRTVNETQRLAVLLRTLGFQALPLHGQLSQSNRLGALNKFKAKARDILVATDVAARGLDIPSVDLVVNFDLPHDSETYVHRVGRTARAGKSGKAVSFVTQYDLEIFQRIEHALGKQVPEEKVSRDEVMVYAERVGEAQRVAVREMKDLHDQRKSGRGGRGGGRGGGRGGRGRGGRRDNMDMDEG
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase RRP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CP143_MYCTU
Sequence: MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS
What are the official names of this protein?
Putative cytochrome P450 143.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: SCIN_STAA1
Sequence: MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGQKAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
What is the function of this protein?
Involved in countering the first line of host defense mechanisms.  Efficiently inhibits opsonization, phagocytosis and killing of S. aureus by human neutrophils.  Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation.  The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium.  Also prevents C5a-induced neutrophil responses (By similarity).
What are the official names of this protein?
Staphylococcal complement inhibitor, SCIN.
What is the protein family that this protein belongs to?
Belongs to the SCIN family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM3_SHESM
Sequence: MSENRIRIATRKSPLAMWQAEFVKAELERVHPGIVVELLPMSTKGDVILDTPLAKVGGKGLFVKELEVAMLEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELPLGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLSERIASFISAEESLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEGGCQVPIGAFAEIHGDEMTLRGLVGNPDGSEIIEGVITGPKTEATKLGVALAEELLSKGAKSILDAVYAKA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: GLUQ_ECO57
Sequence: MLPPYFLFKEMTDTQYIGRFAPSPSGELHFGSLIAALGSYLQARARHGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHHAYREALAWLHEQGLSYYCTCTRARIQSIGGIYDGHCRVLHHGPDNAAVRIRQQHPVTQFTDQLRGIIHADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVSEIVRGADLIEPTVRQISLYQLFGWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALQFLGQQAEAHWQDFSVEQILQSAVKNWRLTAVPESAIVNSTFSNASC
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: Y0700_DICDI
Sequence: MFIINKNLPHFKNDFSDYYSKLDNDLSISSPKFESPVLSQPKVKPLSHDIISICSTKITPLDDFNFLKVISKGGFGKVYLAENKITKKTVAIKVIKKSDTIKKMMVDQVNIEKTILSNYKCNFIVELFSSFQTDKKLFFVMEFLNGGDCASLLRSFNNNMPEDLTKNIIAQIIICLEYLHNHGIIHRDLKPDNILIDSNGHIKLADFGLSKFDFVDESCNIKILKNSFTLYNTNNNNTTENQKILGTPYYIPPEVILGKGYGKTIDWWSLGIILYEFLIGYPPFQEDEPNESINPKSDNDEKNVRIIFNKITNHKKKLYFPKKLYPVAIDLIEKLLDPNPSVRLGANGVDEVKCHPFFSEINWKIYEDQKVLVFQPFVENDCDTSYFIERKEENNKNKINDDIDSLILNQNNQNIYKNNNNNNNNNNNNNNNNNNNNNNDDNDDENNIIDQNLFIDFDFPTY
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0286841.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Protein: RS12_SALHS
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.