PharMolix/UniProtQA huggingface dataset:
Protein: CSN4_NEUCR
Sequence: MVSSEVRDLLAQVPNWSQADRPAAFRTIITTITSSPDPSHFAADLKAVTDAIFLESLGVVATRALVIDLIDALKSLASGGPSADSINSTTSSIWLDVGKAIQQHIQSNPTLATSLVDQTATIYEELLAAAHESQNSFTDAAKTLAAIPLDSSQRRVTDKYKADLWIRIIRNYLEDDDATSAETYLNKLKNIIHNVADDNPVLNLHFKLSAARIQDSNRQFLAASQSYYEISLSPAIAEEERLHTLSMAIKCAVLAPAGPPRSRVLARLYKDERSASLEEFGILEKMFLDRLLARAEVEKFAQGLAPHQLATTSDGSTVLAKAMVEHNLLAVSRLYRNIGFDALGSWLGLDSGNKAEEITARMIEQGRLAGSIDQIDRIIYFESGLEASGEKGSGRAEVPVGKEMRRQDGMVQALAEDLERITDDLLVEFPQLVPAGVPGN
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity).  The CSN complex is involved in the regulation of the circadian clock through its control of the stability of the SCF(FWD1) complex.
What are the official names of this protein?
COP9 signalosome complex subunit 4, Signalosome subunit 4.
What is the protein family that this protein belongs to?
Belongs to the CSN4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LPXK_PELUB
Sequence: MKLKKPKFWDHKKPSFFSYLLLPFSIILGLITKIKSKPKFSNSKIKTICVGNIYIGGTGKTSLAIKIKEILDKNNIRACFIKKFYPNQTDEQKLLSKNGVLFSNLKRITALNEAISEGFEVAIFDDGLQDSTIKYDLEIVCFNNLNWIGNGLTLPSGPLRENINNLKSYENVFLNGNEESLIAIKEQIKRINPNININSGKYIPLNIDEFDKDQNYLVFSGIGNHKTFVEMLKNNKLKIVSDLEYPDHYQYSKKDFDEIIINAKKFNAHIITTEKDYLRLENLNKNEIFYVKSSLDISDEKNLTNKLIKLNEKN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: YZR3_ARATH
Sequence: MSQVDNRNSSAAKRARTDGGRREDDWICPSCGNVNFSFRTTCNMRNCTQPRPADHNGKSAPKPMQHQQGFSSPGAYLGSGGPPPVYMGGSPYGSPLFNGSSMPPYDVPFSGGSPYHFNYNSRMPAGAHYRPLHMSGPPPYHGGSMMGSGGMYGMPPPIDRYGLGMAMGPGSAAAMMPRPRFYPDEKSQKRDSTRDNDWTCPNCGNVNFSFRTVCNMRKCNTPKPGSQQGGSSDKISKQNAPEGSWKCDNCGNINYPFRSKCNRQNCGADKPGDRSNGSPSRAPEENDQ
What are the official names of this protein?
RanBP2-type zinc finger protein At1g67325.
Protein: ARGB_BRUME
Sequence: MTTLENPEMQAQLLSAALPYMQRYENKHVVVKYGGHAMGNPELGKAFARDVALLKQSGVNPIVVHGGGPQIQAMLTKLGIESRFEGGLRVTDEKTVEVVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAQKAHKTVIDPDSNIEKVLDLGFVGEPAEVDRTLLDLLARSEMIPVIAPVAPGRDGHTYNINADTFAGAIAGALAATRLLFLTNVPGVLDKDKKLIKELSVADAQALIRDGTISGGMIPKVETCIDAIRRGVEGVVILNGKTPHSVLLELFTEHGAGTLIVP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOLIN_BPT7
Sequence: MLSLDFNNELIKAAPIVGTGVADVSARLFFGLSLNEWFYVAAIAYTVVQIGAKVVDKMIDWKKANKE
What is the function of this protein?
Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space.  Participates in determining the precise timing of host cell lysis.  Participates with the endolysin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell.
What are the official names of this protein?
Holin, Gene product 17.5, Gp17.5.
What is the protein family that this protein belongs to?
Belongs to the T7likevirus holin family.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass type II membrane protein; Periplasmic side. Note=Classified as a class II holin although it seems to have only one transmembrane domain.
Protein: PA2GA_RABIT
Sequence: HLLDFRKMIRYTTGKEATTSYGAYGCHCGVGGRGAPKXAKFLSYKFSMKKAAAACFKYQFYPNNRCXG
What is the function of this protein?
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids with implications in host antimicrobial defense, inflammatory response and tissue regeneration (By similarity).  Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines (PubMed:2668261).  Contributes to lipid remodeling of cellular membranes and generation of lipid mediators involved in pathogen clearance.  Displays bactericidal activity against Gram-positive bacteria by directly hydrolyzing phospholipids of the bacterial membrane.  Upon sterile inflammation, targets membrane phospholipids of extracellular mitochondria released from activated platelets, generating free unsaturated fatty acids such as arachidonate that is used by neighboring leukocytes to synthesize inflammatory eicosanoids such as leukotrienes.  Simultaneously, by compromising mitochondrial membrane integrity, promotes the release in circulation of potent damage-associated molecular pattern molecules that activate the innate immune response (By similarity).  Plays a stem cell regulator role in the intestinal crypt.  Within intracellular compartment mediates Paneth cell differentiation and its stem cell supporting functions by inhibiting Wnt signaling pathway in intestinal stem cell (ICS).  Secreted in the intestinal lumen upon inflammation, acts in an autocrine way and promotes prostaglandin E2 synthesis that stimulates Wnt signaling pathway in ICS cells and tissue regeneration (By similarity).  May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism and inflammation.  Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines.  Independent of its catalytic activity, acts as a ligand for integrins.  Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1.  Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1.  Induces cell proliferation in an integrin-dependent manner (By similarity).
What are the official names of this protein?
Phospholipase A2, membrane associated, GIIC sPLA2, Group IIA phospholipase A2, Phosphatidylcholine 2-acylhydrolase 2A.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted. Cell membrane; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein.
Protein: TORD_AERS4
Sequence: MQEFLATSERRAELYWWFATLFSAELSDKQIAEYDSYDVRSFLKSLSTLDPMRPAVTELNEAIARLLVRDERATALAADFKGLFLADTAVQPYESAHLDASSLGRMQQRLVRLAIDVSAKYPQPVDHLGVELDLMGNLIIRAAEAPSADQREQWLGEQEAVLHGHLLAWFPHFEVACRAADPFGFYGASARLLGVFLTMDANYLSLVKPASSAD
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAT1_ARATH
Sequence: MGLGGDQSFVPVMDSGQVRLKELGYKQELKRDLSVFSNFAISFSIISVLTGITTTYNTGLRFGGTVTLVYGWFLAGSFTMCVGLSMAEICSSYPTSGGLYYWSAMLAGPRWAPLASWMTGWFNIVGQWAVTASVDFSLAQLIQVIVLLSTGGRNGGGYKGSDFVVIGIHGGILFIHALLNSLPISVLSFIGQLAALWNLLGVLVLMILIPLVSTERATTKFVFTNFNTDNGLGITSYAYIFVLGLLMSQYTITGYDASAHMTEETVDADKNGPRGIISAIGISILFGWGYILGISYAVTDIPSLLSETNNSGGYAIAEIFYLAFKNRFGSGTGGIVCLGVVAVAVFFCGMSSVTSNSRMAYAFSRDGAMPMSPLWHKVNSREVPINAVWLSALISFCMALTSLGSIVAFQAMVSIATIGLYIAYAIPIILRVTLARNTFVPGPFSLGKYGMVVGWVAVLWVVTISVLFSLPVAYPITAETLNYTPVAVAGLVAITLSYWLFSARHWFTGPISNILS
What is the function of this protein?
May play a role in primary carbon metabolism and plant growth, by mediating the transport of GABA from the cytosol to mitochondria.  When expressed in a heterologous system (yeast), imports Arg and Ala across the plasma membrane and exports Lys and Glu, but does not transport proline.
What are the official names of this protein?
Amino-acid permease BAT1, Bidirectional amino acid transporter 1, GABA permease, AtGABP.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid/choline transporter (ACT) (TC 2.A.3.4) family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SURE_METHJ
Sequence: MISGSPPDSTPSHHHFSLKRPCILLTNDDGVNSEGLWAAYDALFEWADVVVCAPATQQSAVGRSLSIFEPLRVNTVSRGDITAYAVGGKPTDSVILALFALGVKPDLVVSGINIGENLSYEAITTSGTVGAALEAANHGYPAVAFSLQIEDQKEKFDDARHLADRFSESKGVVRDVIRRILEKGFPSFTHVMNVNIPSIITGGYEITHLAEHLFITGVEKRLDPRGKPYYWINGPLVTDAPEGTDVHAIHKGNISITPITLDCTAYAGTDDLRRLFSLE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_SHIF8
Sequence: MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: GATC_VESOH
Sequence: MSLSENQVSQIAHLACLSLNEAQLKDNTQNLNTITSLFEQLANIEIDGVEPMLHPLHMFQRLREDVVSEKEQLALFQSIAPKVRNGYYLVPTVIK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: TMM59_PIG
Sequence: MAAPKGSLWVRAQLGLLPLLLLTMALAGGPGTASAEAFDSVLGDTASCHRACQLTYPLHTYPKEEELYACQRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLGCQNQLPFAELRQEQLMSLMPKMHLLFPLTLVRSFWSDVMDSAQSFITSSWTFYLQADDGKIVIFQSKPEIQYAPQLEQEPTNLKESSLSKMSYLQMRSSQAHRNYLEDGENDGFLRCLSLNSGWILTMTLVLSVMVLLWICCATVATAVEQYVPSEKLSIYGDLEFVNEQKLNRYPASSLVLVRSKAEDHDEAGPLPTKVNLAHSEI
What is the function of this protein?
Acts as a regulator of autophagy in response to S. aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C).  Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy.  Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP.  Inhibits APP transport to the cell surface and further shedding.
What are the official names of this protein?
Transmembrane protein 59.
What is the protein family that this protein belongs to?
Belongs to the TMEM59 family.
What are the subcellular locations of this protein?
Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Mainly localizes to late endosomes/lysosomes. Probably first exported to the cell surface and then actively endocytosed to transiently localize in early endosomes on its way to the late endosomal/lysosomal compartment where it becomes quickly degraded.
Protein: COX2_GERVA
Sequence: MAYPFQLGLQDATSPIMEELTNFHDHTLMIVFLISSLVLYLISLMLTTKLIHTNTMDAQEVETVWTILPAIILIMIALPSLRILYLMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMTPTNELKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATITSNRPGVFYGQCSEICGSNHSFMPIVLEMIPLKLFENWSTSMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YCGL_SALTI
Sequence: MRQVTIPLIQSKSMFCVIYRSSKRDQTYLYVEKKDDFSRVPDALMKGFGQPQLAMMLPLDGRKKLVNAELEKVKQALSEQGYYLQLPPPPEDLLKQHLSSVGQNTSHADR
What are the official names of this protein?
Protein YcgL.
Protein: RL21_MESHJ
Sequence: MFAIIKTGGRQLKVEKDQTIFVEKIDKNEGETITFTDILFINGKIGTPYVENASVTGIIEKQGKAKKIVVYRHNPKSTHKRKLGHRQLFTKVKITELKG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: Y3954_ACAM1
Sequence: MPSPAAPRPNRQSRNLQVGEWGEQLVCQWLTQQQWHILDRRWHCRWGEIDIIARSNPPLPGQDSNTRLAFVEVKTRRAQNWDADGLLAITPQKQQKLWKTAQLYLKKHPELAELFCQFDVALVQCNLNSNSPSKTVHVQDDLQVTTVEINQPIHVRGYQFMLLDYIESAFTL
What are the official names of this protein?
UPF0102 protein AM1_3954.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RNS1A_CAVPO
Sequence: AESSAMKFERQHVDSGGSSSSNANYCNEMMKKREMTKDRCKPVNTFVHEPLAEVQAVCSQRNVSCKNGQTNCYQSYSSMHITECRLTSGSKFPNCSYRTSQAQKSIIVACEGKPYVPVHFDNSV
What are the official names of this protein?
Ribonuclease pancreatic A, RNase IA.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: HST2_YEAST
Sequence: MSVSTASTEMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQNIDTLERQAGVKDDLIIEAHGSFAHCHCIGCGKVYPPQVFKSKLAEHPIKDFVKCDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREKITTSGKHPQQPLVIVVGTSLAVYPFASLPEEIPRKVKRVLCNLETVGDFKANKRPTDLIVHQYSDEFAEQLVEELGWQEDFEKILTAQGGMGDNSKEQLLEIVHDLENLSLDQSEHESADKKDKKLQRLNGHDSDEDGASNSSSSQKAAKE
What is the function of this protein?
NAD-dependent histone deacetylase that is involved in nuclear silencing events.  Derepresses subtelomeric silencing and increases repression in nucleolar (rDNA) silencing.  Its function is negatively regulated by active nuclear export.
What are the official names of this protein?
NAD-dependent protein deacetylase HST2, Homologous to SIR2 protein 2, Regulatory protein SIR2 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm, but is largely cytoplasmic owing to efficient nuclear export. Nuclear exclusion is mediated by the exportin CRM1.
Protein: CYSG_ECO55
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: SNPC1_MOUSE
Sequence: MGTPAGAGTRPTGAGTVEGVGIPPGLQTDYETLLSRFQEMDSVRFEDFTELWRSMKFATIFCGKMRNLKKNMFTKEALALAWRYFLPPHTFQIRVGALYLLYGLYNTQLCQPKQKIRVALKDWDEVIRFQQDLMNAQHFDAAFVFRKLRLDRAFHFTAMPKLLSCRMKKKVQQTEVTQKFKDPNDRVMKLITSDVLEEMLNVHDHYQNMKHAISADKSMPDRALSLVKEDFFENIKNIVLEHQEWHKERKNPSLKPKLKDGEENGEGSSEEPERCERAVSLAKIKAKAFSAVVPVSKSRRHRQSKLDSSDSDSGSGQVQGRAAKRKRTREPAGPAGRKRSSRSKGNAPNERKEEKSLHLSMPIITEEEEEDMGGVRKAEFTAPKRKRKC
What is the function of this protein?
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes.  Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes.  Recruits TBP and BRF2 to the U6 snRNA TATA box (By similarity).
What are the official names of this protein?
snRNA-activating protein complex subunit 1, SNAPc subunit 1, Small nuclear RNA-activating complex polypeptide 1, snRNA-activating protein complex 43 kDa subunit, SNAPc 43 kDa subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDGD_AGRRK
Sequence: MNPLELKKAVGSGLLSFPVTHFDNDLKFDEAKYRRHVEWLSGYDAAALFAAGGTGEFFSLNPAEVPQVVQAAKAVAGNTPIISGTGYGTSIAVEIAKSAEKAGADGLLLLPPYLMFAEQEGLIAHVKAVCQSVGIGVIVYNRDNAILNADSIARLTDECPNLIGFKDGVGDVDKVIEITTKLQDRLVYVGGMPTHEVYAQAYFAAGVTTYSSAVFNFVPALAQRFYGALRTGDQATVDEILKGFFFPFVALRNRKKGYAVSIIKAGLRVLGQDPGPVRPPLTDLTPEELAALAQIIETAKAA
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: YBEY_SYMTH
Sequence: MEIWVNNDQEIVEFTEEHEELIRRVAERALELAGAGLGSNVSVSVTLVDDETITDLNRDHRGLASPTDVLSFSQLEGEDMGDLPEGEPMPLGDIVISLERCVSQAAEYGHSFERELGFLTAHGMLHLMGWDHQTPEDEARMMAKTEEILAGLGLSR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_JANMA
Sequence: MNIVILAAGMGKRMQSALPKVLHPLAGKPLLSHVIDTARQLSPSRLCVIYGHGGEQVPQLLQAKDLSFAKQEPQLGTGHAVMQAVPQLDDHTPTLILYGDVPLTTAASLQRLLDSAGNDKLGILTVNLGNPTGYGRIVRENGAITRIVEQKDAKPAELEINEINTGIMVAPTAALKRWLAKLSNNNAQGEYYLTDIVASAVADGVAVVSAQPDHEWETHGVNSKVQLAELERIHQRNIAHALLEQGVTLADPARIDVRGTLTCGRDVTIDVGCVFEGDVSLADGVRIDANCVIHNSTIGARSHVRPYSHFENAVVGAECIIGPYARLRPGTVLAEDVHIGNFVEVKNSDIAAHSKANHLTYVGDSTVGSRVNIGAGTITCNYDGVNKSRTIIEDDVFVGSATQLIAPIRVGKGATLGAGTTLTKDAPADKLTVSRAKQITVDNWQRPVKIKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_GEOTN
Sequence: MNKAPHETRVVVGMSGGVDSSVAALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYEDVVRVCNQIGIPYYAVNFEKQYWDKVFTYFLNEYKAGRTPNPDVMCNKEIKFKAFLEHAMSIGADYVATGHYARVEFRDGEYKMLRGADPNKDQTYFLNQLGQAQLSKVMFPIGHLQKADVRRIAKEAGLATAGKKDSTGICFIGERDFKEFLSHYLPAQPGVMKTLDGEVKGRHDGVMYYTIGQRHGLGIGGSGEPWFVVGKDVRENVLYVAQGFENEYLYSTSLKAVDVNWVSDRKPEAPFRCTAKFRYRQPDIGVMVHPLADGKAEVVFDAPARAVTPGQAVVFYNGDECLGGGTIDEVFRNGEKLWYVG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_COXB2
Sequence: MDEKIETRLIGATMQSNEPDLERSIRPKRLSDYIGQAAVREQMDIFIRAATNRREALDHVLIFGPPGLGKTTLAHIIAHEMQAGLKQTSGPVLEKAGDLAALLTNLEPHDVLFIDEIHRLNPAIEEVLYPALEDFQLDIIIGEGPSARSIKLDLPPFTLVGATTRAGLLTSPLRDRFGIVQRLEFYRIPDLIHIVKRAAHILNVVIDENGAGEIARRSRGTPRIANRLLRRVRDFAEVRANGMINESIAKEALDLLNVDIRGLDVMDRKLLETIIKKFQGGPVGIESLAAAISEERGTIEDVIEPYLIQEGFILRTPRGRIATELTYQHFKLPLPTQSTLQENFDLLGKVE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.