PharMolix/UniProtQA huggingface dataset:
Protein: YENA2_YERET
Sequence: MSNSIEAKLQEDLRDALVDYYLGQIVPNSKDFTNLRSTIKNVDDLYDHLLLDTQVSAKVITSRLSLVTQSVQQYINRIALNLEPGLSINQQEATDWEEFANRYGYWAANQQLRMFPEIYVDPTLRLTKTEFFFQLESALNQGKLTDDVAQKAVLGYLNNFEEVSNLEIIAGYQDGIDIENDKTYFVARTRMQPYRYFWRSLDASQRNANSQELYPTAWSEWKAISVPLENVANGIVRPIMMDNRLYISWFEVAEEKETDSDGNIIVSGRYRTKIRLAHLGFDGVWSSGTTLREEVLADQMEEMIAVVDRMEDEPRLALVAFKEMSESWDVVFSYICDSMLIESSNLPTTTHPPKPGDGDKGLSDLDDYGANLVWFYLHETANGGKAEYKQLILYPVIINRDWPIELDKTHQGDFGTVDDFTLNSNYTGDELSLYLQSSSTYKYDFSKSKNIIYGIWKEDANNNRCWLNYKLLTPEDYEPQINATLVMCDKGDVNIITGFSLPNGGVDAGGKIKVTLRVGKKLRDKFQIKQFSQTQYLQFPEASSADVWYIGKQIRLNTLFAKELIGKASRSLDLVLSWETQNSRLEEAILGGAAELIDLDGANGIYFWELFFHMPFMVSWRFNVEQRYEDANRWVKYLFNPFECEDEPALLLGKPPYWNSRPLVDEPFKGYSLTQPSDPDAIAASDPIHYRKAVFNFLTKNIIDQGDMEYRKLQPSARTLARLSYSTASSLLGRRPDVQLTSFWQPLTLEDASYKTDSEIRAIEMQSQPLTFEPVVHDQTMSAVDNDIFMYPMNNELRGLWDRIENRIYNLRHNLTLDGKEINMDLYDSSISPRGLMKQRYQRVVTARNASKMNFKVPNYRFEPMLNRSKSGVETLIQFGSTLLSLLERKDSLSFDAYQMIQSGDLYRFSIDLQQQDIDINKASLEALQVSKQSAQDRYDHFKELYDENISSTEQKVIELQSQAANSLLMAQGMRTAAAALDVIPNIYGLAVGGSHWGAPLNAAAEIIMIKYQADSSKSESLSVSESYRRRRQEWELQYKQAEWEVNSVEQQINLQNMQIKAANKRLEQVEAQQQQAMALLDYFSERFTNESLYTWLISQLSSLYLQAYDAVLSLCLSAEASLLYELNLGEQSFVGGGGWNDLYQGLMAGETLKLALMRMERVYVEQNSRRQEITKTISLKALLGESWPAELNKLKQKTPINFNLEEQIFVEDYQELYQRRIKSVSVSLPMLVGPYEDVCAQLTQTSSSYSTRADLKTVENMLTKRTFADTPHLVRSIQPNQQISLSTGVNDSGLFMLNFDDERFLPFEGSGVDSSWRLQFTNLKQNLDSLNDVILHVKYTAAIGSSTFSQGVRKILANINNDE
What is the function of this protein?
Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae (PubMed:21278295, PubMed:22158901).  The TC has an endochitinase activity (PubMed:21278295) (Probable).
What are the official names of this protein?
Toxin subunit YenA2.
What are the subcellular locations of this protein?
Secreted. Note=Secreted when grown at 25 degrees Celsius or less, but not when grown at 30 or 37 degrees Celsius.
Protein: DEOC_THEP3
Sequence: MNIAKMIDHTLLKPNATKSEIEKLCNEAKEYGFASVCINPCFVDLAYSMLKDTDVKVCTVIGFPLGANTIESKVFEAVDAVKRGATEVDMVLNVSMLKSGDYDYVKKEIEEVVKAVKSYGDIVVKVILETCYLTDEEKVKACQLTREAGADFVKTSTGFGPGGATVEDVKLMRQTVGENFGVKASGCVRTAEDAKAMIEAGANRIGASAGVKIAEEWNKLKMS
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_RHORT
Sequence: MTNHWDVIVVGGGHAGTEAAAAAARLGAKTLLATHKLETVGTMSCNPAIGGLAKGHLVREIDALDGVMGRAIDRGGIQFRILNRSKGPAVRGPRAQADRALYAQAVRAILADQPGLTLAALAIEDLLIGNDGRCAGVIDAEGGVHRAGAVVLTTGTFLRGVIHIGTQTTPAGRIGEAPALGLSATLARLGFPLGRLKTGTPPRLDGRTIAWATLESQPGDEPPPPFSFLTTAITTPQISCAITETTAETHRVIRENLHRAPLYSGQIQGVGPRYCPSIEDKVVRFADRDRHQIFLEPEGLDDPTVYPNGISTSLPIDVQLALLATIPGLEKAEMMRPGYAIEYDFVDPRCLGPTLETDRLPGLFLAGQINGTTGYEEAAAQGLIAGLNAARVAGAGERAAPITFDRAEGYLGVLVDDLITLGTTEPYRMFTSRAEYRLLLRADNADLRLTAKGIALGCVGAARTAAFEDKRAALTAARTMIDGLALTPPDLARRGIAVNQDGQRRTPLDLLCHADIDWARLVALWPELGAIRPDVAEQLEIGARYAGYLERMHGDVAAFRRDEALVLPADLAYDGLANLSAELRGKLTLARPATLGAAARIPGMTPAALTALLRHVKRRERDSVEECFT
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAK_ACTMI
Sequence: MTLPFAEWLPKQRWYAGRSRVLASVKEASATPLGEELDLVLVDVEYTDGSSERYQVMVGWGDGPLPEYSTIASIGTADDGRDGYDALYDPRATRHLLGLVDTSATAGDVTFEKEPGVELPLEAWPRVFDAEQSNTSVIFDEDAILKLFRRVTCGVNPDIELNRVLGRAGNPHVARLLGSLQSADDSGPCSLGMVTEYAANSAEGWAMATASARDLFADAEMRADEVGGDFQGESYRLGEAVASVHRTLAEELGTGPAPFPLDAVLARVRTAAAAVPELQQFVPAITARFEALTGAEVVVQRVHGDLHLGQVLRTPEAWLLIDFEGEPGQPLDERRMPDSPLRDVAGVLRSYEYAAYQLLVDQDDDEHLAARAREWVDRNRAAFCDGYTNVAGADPREQGALLSAYELDKAVYEAAYEARHRPGWLRIPLRSITRLVG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate.  Only maltose acts effectively as phosphoryl-group acceptor, but maltotriose, maltotetraose, maltopentaose, and maltohexaose show a weak potential to replace maltose.  ATP is not replaceable as phosphoryl-group donor.
What are the official names of this protein?
Maltokinase, MaK, Maltose-1-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the aminoglycoside phosphotransferase family.
Protein: PURA2_CHICK
Sequence: MAEHGAPAPAIPNGGCAARLPGNKVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPKVTAFIGNGVVIHLPGLFEETEKNLKKGKGLEGWEKRLVISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFDEFSERFKVLANQYKAIYPTLEIDIEGELKKLKAYMEKVKPMVKDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQMRGKEFGVTTGRKRRCGWLDLVQLRYAYMINGFTALALTKLDILDVFPEIKVGVAYKLDGEVIPHFPANHEVLSKVEVKYETLPGWDTDISNARTFDELPVNAQNYVRFIEMELGVPVKWIGVGKSRESMIQLF
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase isozyme 2, AMPSase 2, AdSS 2, Adenylosuccinate synthetase, acidic isozyme, Adenylosuccinate synthetase, liver isozyme, L-type adenylosuccinate synthetase, IMP--aspartate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: KLRG1_MOUSE
Sequence: MADSSIYSTLELPEAPQVQDESRWKLKAVLHRPHLSRFAMVALGLLTVILMSLLMYQRILCCGSKDSTCSHCPSCPILWTRNGSHCYYFSMEKKDWNSSLKFCADKGSHLLTFPDNQGVKLFGEYLGQDFYWIGLRNIDGWRWEGGPALSLRILTNSLIQRCGAIHRNGLQASSCEVALQWICKKVLY
What is the function of this protein?
Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands.  May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
What are the official names of this protein?
Killer cell lectin-like receptor subfamily G member 1, Mast cell function-associated antigen 2F1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: PAND_PSYA2
Sequence: MLLNMLKCKLHRARVTHAELHYEGSCGIDGDLLDLAGLRENESIDIYNVTNGKRFRTYAIRAEAGSGIISLNGAAAHMADLGDIVIICAYAHFDEVEASTYQPRLVYCNEDNTVKDTANIIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GE_CHV9D
Sequence: MRMTVVKHVMLTLICGTLSWGVQINTLAYASAIKSEDGFDMDEDGVYGDDIQDYINAAYTHERPFIQDKSKHKMETYTQSLLHTDLETDSQISRERGNYINAQELGDGNNEHVDLVNRTMTKNVLMKHGHRNFMDASILYKSVHGITHLHAHQRPTEVSVAENQQLLLKVHIPQENEHTYTERWSFLPAAPCKLTPPSIQQVCIKHGACIHDVVVDVDCIAESMEHTLVEIGYVVHASKAVHPTWTVVNITEDFANYGFDTPDVKPGVLKFEHMNAHHAGVYIWNLQGTHGENMYVTFLVKLNNSIENHIDLPAVTPKPKGAEFHTWHYHSHVFSVGETFSLPMHLQYKIHDTPFDLLLEWLYVPINPTCQPMRLYSACVYHETVPSCLSPENPECTFASPHIARRVANTVYQNCEHVNYTADCLAVSHVEPGSGLEIQNGGSALLFVNAAESMSGLYVFIIHFNGHVETVAYTVVSTIENFVNAIEEHGFPPEIHNVPSPSSPNVTANNDVISETNTFPFKTYAGITGGFAVLALVCLALALVCTKRKFGHRSYWSDKAAYGQSTYYAGVPVDDFEDDTEVEVDEGAECGGSGYTVYIDKRTR
What is the function of this protein?
In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions.  Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions.  Implicated in basolateral spread in polarized cells.  In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.  Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips (By similarity).
What are the official names of this protein?
Envelope glycoprotein E, Membrane glycoprotein 2, gE.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein E family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host cell junction. Host Golgi apparatus membrane; Single-pass membrane protein. Host endosome membrane; Single-pass membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN), maybe through an interaction with PACS-1 sorting protein. The heterodimer gE/gI then redistributes to cell junctions to promote cell-cell spread later in the infection (By similarity).
Protein: ALB1_LODEL
Sequence: MAGRNAINKPKIKMLAQSHARSLSRKRAARSSVQTRSSTSRYASKSLTAPRPTDSKSLALYTGETPLSQSVMTTNTLSKKRAKKIARNQKYLSQKQEDELMMDMDKQMKEKSRLDKVKKALWDLIENFEKNGPTVLPTGEGTTLGVQSF
What is the function of this protein?
Involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.  Accompanies the pre-60S particles to the cytoplasm (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein ALB1.
What is the protein family that this protein belongs to?
Belongs to the ALB1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYOE_BAUCH
Sequence: MIRLYLQATKPGIVLSNLMSFIGGFLLASKGRINYLIFLVTLLGVLFIVTAGCVLNNIIDRDIDRKMERTKNRPLAIGSISILTCLIYALICSIIGIYLLYNYTNKLTMLLAIIGLIVYVGIYTKCMKRQSIYSTIIGSFSGAIPPVIGYCAVSNQFDTGALLLLLIFCLWQMPHSYAIAILRLQDYQAASIPILPIKKGIRITKNHIVIYIVAFIVTTILLNISGYTTSYQYLIVTNFINFWWLYLALQGYKEDNNDILWSKKMFIFSIIAITSLSLMMSLDSIFSR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KDSA_BRUA4
Sequence: MATANSSVKIGNVTFSNSAPFALIAGPCQMETREHAFDMAGRLKEMTDKLGIDLVYKSSFDKANRTSLKAERGIGLEKAMEVFADLKKEFGFPVLTDIHTEEQCAAVAPVVDVLQIPAFLCRQTDLLIAAAKTGRVVNVKKGQFLAPWDMKNVLSKITESGNPNVLATERGVSFGYNTLVSDMRSLPIMAGLGSPVVFDATHSVQQPGGHGGSSGGQREFVETLARAAVAVGVAGLFIETHQDPDNAPSDGPNMVPVDKMPALLEKLMAFDRIAKGL
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YC66L_SYNY3
Sequence: MVNFGLNSASILGIFLAVAGAGLYFLRSVRPEVSRDYDIFFSAVGLLCGLILLFQGWRLDPILQFGQLLLSGSTVFFAAETIRLRGITTEQARRSAPYADDRRVSKTRVYTEAELDQLEPEDEPVARNNRRLRGYDDDARSGRPDGYGEAEARPRPRSQGRNAPPTNPNPRPTRSRPSAGRSAPQRPGPAPGYNDNYGYEDDYSGWESGANDVWDDPTPSRRPPTRRPRPEAGNDPAPSRRPRPSNNPPNDSFGDRPERNAPRNARPYEDEPPAAYVDYQPIDEADLTPRPTTPEDPADRNQEQSRSGNPRSQRPSRSPVDGEEPPIGADDQERFDY
What are the official names of this protein?
Ycf66-like protein.
What is the protein family that this protein belongs to?
Belongs to the ycf66 family.
Protein: YIPL1_ARATH
Sequence: MGRLFVIDLEGLVYSCKYCQTHFAVTNDIISKSFHCKHGRAYLFDNVVNVTVGEKEHRVMITGWHTVADIFCVSCGSLVGWKYEIAYDKSQKYKEGKFILERFKVLGPYGGGYDMNQNEPMTGSDDEE
What are the official names of this protein?
Protein yippee-like At3g08990.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
Protein: HEM6_BORPE
Sequence: MTAVAIPAVRDYLTDLQGRIVAALEQAGGEAFRTDAWQRAEGGGGVSRLLEGGQLFERAGVLFSHVKGTRLPPSASAHRPELAGRGWEAMGVSMVLHPRNPYVPTTHMNVRMFVAAARPGHAESDVFWFGGGLDLTPYYPFEDDARHFHRACRDALDPHGADYYPRYKQWCDEYFFLKHRNETRGIGGIFFDDLNEPGFDASFALTCSVGDSFLPAYLPIVQARRDMPYGERERDFQAYRRGRYVEFNLVFDRGTLFGLQSGGRTESILLSMPPLAQWRYDWQPQAGTPEAALAEFLRPREWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_PROMP
Sequence: MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRIKALEIAHQRGLDLVLVSEKANPPVCRIMDYGKYKFEQEKKAKETKKKSHQTEVKEVKMRYKIDKHDYDVRIGQAVRFLKSGDKVKCTVFFRGREIQHSNLAETLLLKMANDLEEQSEVQQRPKREGRNMIMFLSPRKTPLIKKEEG
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPB_VIBVU
Sequence: MSFEVLEKLEAKIQTAVDTIALLQMEVDELKEDKAKLETEANELRAQREQLEQKAQQTQQEHAQWQERIRALLGKMEDVE
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: SSU72_CAEEL
Sequence: MEYSSKLRFAVSCSSNMNRSMEAHGILKKRGFNIESYGSGNQVKMPGPTVDKPNCYEFGPTTYEDIYADLTNKDLHLYTQNGLLHMVDRNRRIKSRPQRFQAETREFDIVLCLEERVFDQVVDFLNRSVGKSGNPVHVINIDIEDNAEEATFGAFFVADLCEKLERSEDFEEDIDQIITDLEENNPKRNLLHTICFY
What is the function of this protein?
Protein phosphatase that dephosphorylates 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the large RNA polymerase II subunit ama-1 (PubMed:26588990).  By regulating the phosphorylation status of ama-1 and thus ama-1 binding to specific polyadenylation sites, regulates alternative polyadenylation of pre-mRNAs, including unc-44 and dlk-1 mRNAs (PubMed:26588990, PubMed:28087624).  This results in the tissue-specific expression of unc-44 isoforms (PubMed:28087624).
What are the official names of this protein?
RNA polymerase II subunit A C-terminal domain phosphatase ssup-72, CTD phosphatase ssup-72.
What is the protein family that this protein belongs to?
Belongs to the SSU72 phosphatase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GET2_CANAL
Sequence: MSEPVVDTAELSAEEKKRLLRERRQAKMSKGKATARLNDILSQGSSVKTSGVKSVLDQEKEATPSHDEDPEIQDITEITTPPPRTPPIGEDAPQDIDKIFQSMLQQQGQGADTAGDPFAQIMKMFNQVEGGDSPPSESATSTQDPAELKYRQELLEYNTYNQKLWKFRFLLVRVSVTLFNFFYHYINLSNFHASNYAYVRDLSSEKYPVRDFFTWFATTEVVLVAAYYSIFHSLGLFHAANQNSFVLKAMSMGSMVLPQLEHYKPLVARFLGYYELLGIVLGDLSLVIVLFGLLSFAN
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 2.
What is the protein family that this protein belongs to?
Belongs to the GET2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RAD1_MOUSE
Sequence: MPLLTQYNEEEYEQYCLVASLDNVRNLSTVLKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQADVFQEFVIQEESVTFRINLTILLDCLSIFGSSPTPGTLTALRMCYQGYGHPLMLFLEEGGVVTVCKITTQEPEETLDFDFCSTNVMNKIILQSEGLREAFSELDMTGDVLQITVSPDKPYFRLSTFGNAGNSHLDYPKDSDLVEAFHCDKTQVNRYKLSLLKPSTKALALSCKVSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPDEEVPES
What is the function of this protein?
Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair.  The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex.  Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER).  The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates.  The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase.  Isoform 1 possesses 3'->5' double stranded DNA exonuclease activity (By similarity).
What are the official names of this protein?
Cell cycle checkpoint protein RAD1, mRAD1, DNA repair exonuclease rad1 homolog, Rad1-like DNA damage checkpoint protein.
What is the protein family that this protein belongs to?
Belongs to the rad1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSL4_STAAE
Sequence: MKITTIAKTSLALGLLTTGVITTTTQAANATTPSSTKVEAPQSTPPSTKIEAPQSKPNATTPPSTKVEAPQQTANATTPPSTKVTTPPSTNTPQPMQSTKSDTPQSPTTKQVPTEINPKFKDLRAYYTKPSLEFKNEIGIILKKWTTIRFMNVVPDYFIYKIALVGKDDKKYGEGVHRNVDVFVVLEENNYNLEKYSVGGITKSNSKKVDHKAGVRITKEDNKGTISHDVSEFKITKEQISLKELDFKLRKQLIEKNNLYGNVGSGKIVIKMKNGGKYTFELHKKLQENRMADVIDGTNIDNIEVNIK
What is the function of this protein?
Secreted protein that plays a role in immune innate response inhibition by interfering with host TLR2-mediated pathway.
What are the official names of this protein?
Staphylococcal superantigen-like 4.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal/streptococcal toxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RK14_NANDO
Sequence: MIQPQTHLNVADNSGARELMCIRIIGASNRRYAHIGDVIVAVIKEAVPHMPLQRSEVIRAVIVRTRKELKRDNGMIIQYDDNAAVVIDQEGNPRGTRVFGAIARELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NQOR_PHOLL
Sequence: MTKILVLYYSMYGHIEALASAVAEGAKKVADVEVTIKRVPETIPPEAFTKAGGKVDQSAPVASVQELVDYDAIIIGTPTRFGNMAGQMRNFLDQTGGLWAEGKLYGKVASVFTSTGVGGGQEMTITSTWTTLAHHGFIIVPIGYGIPEIGDISQMQGGTPYGASTIADGDGSRIPNENELKIARYQGEHVAKIAKKLKD
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: ECP_RAT
Sequence: MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF
What is the function of this protein?
Cytotoxin and helminthotoxin with ribonuclease activity.  Possesses a wide variety of biological activities (By similarity).
What are the official names of this protein?
Eosinophil cationic protein, ECP, Eosinophil secondary granule ribonuclease 11, EAR-11, Ribonuclease 3, RNase 3.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Protein: PRMA_SYNFM
Sequence: MNGEWIGIDVACGPDVADDVAAELAGTFGVSVEFRSTGIRFYLDAGSAPHDWRTTLEGILREMGTRRFPGASFPYSVSTLAGDDWADGWKAYFKPLRVGKHLVVCPTWEEFAPDAGDRIIRMDPGRAFGTGQHETTRLCLEWLEDRALQALPSAPGSLLDVGTGSGILAVAAALLGFHPVQAVDDDPEAVEVAAENIALNGMESAIELLAGTARQASGAFDVVIANIQAIPLVGMASELVRLTAPAGLAALSGILVEQGEVVKSAYRDLGLLPRKMRTAGEWCLLEFKKP
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_SALEP
Sequence: MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IF1A_DESA1
Sequence: MRCLSKKHQKQGDEHGGEIPLPNPDEGTIICGVVRHLGGDYLIAKCLDGVDRKIRIPGKLRRKVWITEGDIILVGLWDFSSEKGEVVYKYGKNEVNKLVEKGVVPKEFIDALSELI
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: RR4_IRILU
Sequence: RFKKIRRLGALPGLTSKRPRSGSDPKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKDKQRSKALIQNYIASSPHEELPNHLTIDPFQYKGLVNQIIDSKWIGLKIN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.