PharMolix/UniProtQA huggingface dataset:
Protein: MDR1_TRIRC
Sequence: MASQPPQPLSGQPVTQYEEYQSEVITETTNRPTPAADIYEITPTNDVMDDRYEHEHDDYESGAMYETVRTWSPQSRPELVRIASVFSRVDSHPNVTPTTEDGGQLNRRDTLAGVKIGDPVLDPTKPEFDFYKWARMFTHVMENEGIKRNRTGVMFRNLTVLGSGSAVQYQDTFLSPFAAPFRPGELCGKGRNPEKVILHDFNGAIREGELLMVLGRPGSGCSTFLKAICGELHGLQKKKESIIHYNGVSQHTFKKELRGEAVYSAEDEHHFPHLTVGQTLEFAAAARTPSKRVLGVSRKDFSTHLARVMMSVFGLSHTYNTKVGDDYVRGVSGGERKRVSIAEIALSGAPICCWDNSTRGLDSATALEFTKALKIGSQVGGITQCLAIYQASQAIYDIFDKVIVLYEGRQIFFGPTRIAKQYFEEMGWYCPPRQTTADFLTSVTNPKERIAKEGYENRVPRTAVDFERYWKQSQNNKLLLANMDRFEAEYPPEEGHLQKLRETHGQAQAKHTTSKSPYRISVPMQVKLCTVRAYQRLWGDKSSTIATNISQIMMALIIGSLFFDTPQTTDGFFAKGSVIFFAILLNGLMSITEINGLYAQRPIVVKHVNFAFYHAYSEALAGIVADIPIKFLLALVFNIIIYFLGGLERSAAKFFIFFLFTFITILTMSAIFRTLAAATKTIPQALALAGVMILALVIYTGFALQPSYMHPWFKWILYINPIAYAYEALLVNEVHGNRYRCATPVPPYGGGKNFACAVAGAVPGEMSVSGDAWVESSYDYSYAHIWRNLGILLGFLAFFYFVYLMVSELNLSSASSAEFLVFRRGHLPKSFQGSKDEEAAAGGVMHPNDPARLPPTNTNGAAGETAPGGSTVAVIPPQKDIFTWRNVTYDITIKGEPRRLLDNISGWVRPGTLTALMGVSGAGKTTLLDALAQRTTMGVITGDMLVNGRPLDSSFQRKTGYVQQQDLHLETTTVREALRFSADLRQPKSVSRKEKYEYVEDVIKMLSMEDFSEAVVGNPGEGLNVEQRKLLTIGVELAAKPQLLLFLDEPTSGLDSQSSWSIVTFLRKLADNGQAVLSTIHQPSGILFEQFDRLLFLAKGGRTVYFGDIGKNSETLLNYFETHGAEPCGPSENPAEYMLNIVGAGPSGKSKIDWPVVWKESEESRHVQQELDQIQSETSKKNEGHGQSAEKEPGEFAMPFTSQLYCVTTRVFQQYWRTPSYIWGKFLLGLASALFIGFSFFLQNSSMAGLQNSLFSIFMLTTIFSSLVQQIMPRFVTQRDLFEVRERPSRAYSWKVFLLANIIVEIPYQILLGIIAWASLFYPTFGAHLSSERQGILLLYCVQFFIFASTFAQMIIAGLPDAETAGGIATTMFGLMVTFNGVLQKPNALPGFWRFMWRVSPITYTVGGLAATSLHNREVKCAQNELAIFDPPTGATCAQYLQKLVEAGAPGKLYNPTSTTQCQYCPLSSGDQFLGGSEIHWSDRWRNFGIGWAYIVFNIFATVALYYLIRVRKSSGRPNRIISVIMYHLSRAGTYCRAFITGRKEKCPRKREQIVQTYKEFNMLLN
What is the function of this protein?
Pleiotropic ABC efflux transporter involved in the modulation susceptibility to fluconazole, voriconazole and miconazole, 3 azoles with similar molecular structure.
What are the official names of this protein?
ABC multidrug transporter MDR1, Multidrug resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURA_LACCB
Sequence: MGTVVIVGTQWGDEGKGKITDFLSQGAKVVSRYQGGDNAGHTIHANGEVYKLRLVPSGVLYPHQLSVIGNGVVVNPKSLVGELARLAEQGVTGENLRISDRAHVILPYHIKLDKLQEAAKGADKIGTTNRGIGPAYMDKAARVGIRMADLLDKEIFEERLKANLKAKNEEFVKVYDSTPMNFDDIFEEYYQYGQQLKQYVCDTSIVLNDAIDKSEHVLFEGAQGIMLDIDQGTYPFVTSSNPAGGVTVGAGVGASKIDRVVGVAKAYTSRVGDGPFPTELLDKTGDFIRNAGHEFGTVTGRPRRIGWFDAVVVRHSRRVAGITDLCLNSIDVLTGLDKVKICVAYERDGERVENYPASLKFLSECKPVYEELPGWQEDITKAKTLDDLPENARRYVERITELLGVDLLTFSVGPDRDQTNVLENVWDKVSR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_METSB
Sequence: MAREGEGGRGRDREERDSEFMDRLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATESAKRSLIRVPLREGRTLHHDVNGRHGAGRVVLRAAPAGTGIIAGGPMRAIFETLGMHDVVAKSQGSSNPYNMVRATFDALGRQDSPRAVAARRNLKVSVLQGRRPGGEAEAASEA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SRCR1_PATPE
Sequence: MTSLRRGNICWVAVCAALLTLTRGIDVIAKPSRTPSNGDVQLVGGASPAEGRVEVFYNGAWGTVCDDGWEMQDAQIVCKQLGFASANSTRCCASFGQGTGVIILDDLACTGDETRIGDCPHRGWEQHNCAHTEDAGVVCNGKVRLAGSPNPLQGRLEIFHEGEWGTVCDSDWDLKDASVVCRQLGYPSANSSSNVSFGPASTAQILLDRVSCMGDEHGVEYCEHGDWKNVSADCTHSRDAGVICTRPIRLVGGNGPMQGRVEILHNGEWGSVCDKGWSFQNAVVVCNQLGATQPRRPQGVPVGGGVGPTHMSFVNCDGTEATLEQCSNSGWGNAGECGHSNDAGVICTPAVRLVGGNTHIEGRVEVFNNGQWGSICPESWDAKDAEVACRQLGNYPLAEGDCCPQFPADVGVVLDNVVCTGNESRIQDCAHQDWGVVDCSGGQAAGAKCQATVQLVGGSHPLEGNVIVLRNGRWGSICDDNWDINDARVVCRQLGNYEAVAATCCAKYGQVPQEIILDDVACQGEEGRIEDCYHATWGSHNCGGSESAGVVCREIRLALDDSSSNLPKGRVEIVYNGVWGRICGTDWDLNDANVLCRQLYNSTAESVHSFKNGSGPILLSNFKCTGSESNIFDCTHNPWGDYTCDDADAAVVCRGGLRLAGGRTPLEGRVEVFHDGQWGTVCDDGWDLLDAKVVCTQLGNYEALSAKCCANFGQGTGPILIDGLACNGNEDLIEDCRHEGWGSHNCQHYEDAGVVCTDLRLTHENGSVSTNTLTGRVEVLSSSGEWGAICGKYWDKKDAEVVCQQLFNTSAMDTRKFYLSSPDQLINMGEVQCNGSESLLLQCPRASKPFTAQTCPGGETAGVLCKDIRLVSGNQREFGAVELLVDSQWGSICADNWGPNEGAVACKQLGYCAAKGTQKGLQPARTQGKMHFSSMNCTGSESRLRDCVHTYGGYTCNGLVFEAVVQCKAGCDWPGPIRHGSFSPNRSSYDPLTTIDVKCDAGYELMGSKTLQCVTGCDWSRPTPECQRISNCSIGGGGKPSVGAQAGPAGGVMLIIGIILGAVVMMLIACVALYLKGRNKNIGRGNPATTSAIWKPKKEFDELKEPVLSFSAMTAGGAGPEDGMGEDI
What is the function of this protein?
Involved in aggregate formation and phagocytosis by larval mesenchyme cells and adult coelomocytes.  Binds to bacteria and may act as an opsonin in the innate immune system.
What are the official names of this protein?
Scavenger receptor cysteine-rich domain superfamily protein, ApSRCR1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein.
Protein: UBB_PANTR
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGC
What is the function of this protein?
Exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
What are the official names of this protein?
Polyubiquitin-B.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus. Mitochondrion outer membrane; Peripheral membrane protein.
Protein: RL32_STAAE
Sequence: MAVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGEYKLSHRVCKNCGSYNGEEVAAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: X_HBVB6
Sequence: MAARVCCQLDPARDVLCLRPVGAESRGRPLPGPLGTLPPASPPAVPTDHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHGNLPKVLHKRTLGLSAMSTTDLEAYFKDCVFNEWEELGEEIRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: YCF3_NANDO
Sequence: MPRSRINGNFIDKTFSIVANILLRIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEATRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIQQGDSEIAESWFDQAAEYWKQAIALTPGNYIEAHNWLKITRRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RBM22_CHICK
Sequence: MSTSLGSNTYNRQNWEDADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPGVRMRFKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSLKDEMPKSDVNKEYYTQNMEREIANSDGTRPVGALGKATSTSDMLLKLARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQDIKDRYYGINDPVADKLLKRASTMPRLDPPDDKTITTLYVGGLGDTITESDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKDKEGTTESGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFHAMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSSP
What is the function of this protein?
Required for pre-mRNA splicing as component of the activated spliceosome.  Involved in the first step of pre-mRNA splicing.  Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle.
What are the official names of this protein?
Pre-mRNA-splicing factor RBM22, RNA-binding motif protein 22.
What is the protein family that this protein belongs to?
Belongs to the SLT11 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nearly exclusively nuclear. May be shuttling between the nucleus and the cytosol.
Protein: CATB_MACFA
Sequence: MWWLWASLCCLLALGDARSRPSFHPLSDELVNYVNKQNTTWQAGHNFYNVDVSYLKRLCGTFLGGPKPPQRVMFTEDLKLPESFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGIMCGDGCNGGYPAGAWNFWTRKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
What is the function of this protein?
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity).  Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity).  Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity).  Has also been implicated in tumor invasion and metastasis (By similarity).
What are the official names of this protein?
Cathepsin B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Melanosome. Secreted, extracellular space. Apical cell membrane; Peripheral membrane protein; Extracellular side. Note=Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells.
Protein: RL29_GEODF
Sequence: MKASDLNKSTVDELRSTEAELTKELFNLKFQLHTGRLEDTSKPARIKKDIARVKSVLRAKRG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SODC_CAUVC
Sequence: MIRLSAAAALGLAAALAASPALAQTSATAVVKAGDGKDAGAVTVTEAPHGVLLKLELKGLTPGWHAAHFHEKGDCGTPDFKSAGAHVHTAATTVHGLLNPDANDSGDLPNIFAAADGAATAEIYSPLVSLKGAGGRPALLDADGSSIVVHANPDDHKTQPIGGAGARVACGVIK
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).  May function against extracytoplasmic toxic oxygen species.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYL_SHISS
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNMLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVLVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_SHEPA
Sequence: MFLAQEIIRKKRNAETLSTEEIQFFVKGITNNTVSEGQIAALGMAVYFNDMNMDERIALTTAMRDSGTVLNWQSLDLNGPIIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAIPGYNTEPDSALFRKVVKEAGVAIIGQTGDLVPADKRFYSIRDNTATVESISLITASILSKKLAAGLDALAMDVKVGTGAFMPTYEASEELARSITAVANGAGTKTTALLTDMNQVLASCAGNALEVKEAVDFMTGAYRNPRLYEVTMGLCAEMLVLGGLASNESEARVKLNTVLDNGKAAEIFGRMVSGLGGPADFVENYSKYLPDSQIIRPVYADRSGFASAMDTRELGLAVVTLGGGRRKPGDALDYSVGLSKVCALGDEINPEQPIAFIHAQSESAFAEAEAAVKKAIHIGDSKPEKTPEIYRYIRESDL
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: CWC25_HUMAN
Sequence: MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEKNFMKR
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC25 homolog, Coiled-coil domain-containing protein 49, Spliceosome-associated protein homolog CWC25.
What is the protein family that this protein belongs to?
Belongs to the CWC25 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_RHOP2
Sequence: MASEDPSVSGVSGRYATALFELARDEKVVDAVTADLDKFKAMLADSPDLLRLVRSPVFGAEAQAKALGAVLDKAGITGISANFLKLLAANRRLFVVADVIRAYRALVAKFKGEATADVTVAETLGDKNLEALKAALKAVTGKDVTLNINVDPAIIGGLVVKLGSRMVDSSIRTKLNSIKHAMKEAG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RISB_SALHS
Sequence: MNIIKANVAAPDARVAITIARFNQFINDSLLDGAVDALTRIGQVKDDNITVVWVPGAYELPLATEALAKSGKYDAVVALGTVIRGGTAHFEYVAGGASNGLASVAQGSGVPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PLPP6_BOVIN
Sequence: MQSPRRNAEGRPLGTCDPSSSGSPAHGGGSRFEFQSLLSSRMPGADPTSARLRASESPVHRRGSFPLAGAGSSQALPPQLPEEDRIDLNPSFLGIALRSLLAIDLWLSKKLGVCAGESSSWGSMRPLMKLLEISGHGIPWLLGTLYCLSRSDSWAGREVLMNLLFALLLDLLLVSLIKGLVRRRRPAHNQMDMFFTISVDKYSFPSGHTTRAALVSRFILNHLVLAIPLRVLVVLWAFILGLSRVMLGRHNVTDVAFGFFLGYMQYSIVDYCWLSPRTAPVLFVLWNQP
What is the function of this protein?
Magnesium-independent polyisoprenoid diphosphatase that catalyzes the sequential dephosphorylation of presqualene, farnesyl, geranyl and geranylgeranyl diphosphates.  Functions in the innate immune response through the dephosphorylation of presqualene diphosphate which acts as a potent inhibitor of the signaling pathways contributing to polymorphonuclear neutrophils activation.  May regulate the biosynthesis of cholesterol and related sterols by dephosphorylating presqualene and farnesyl diphosphate, two key intermediates in this biosynthetic pathway.  May also play a role in protein prenylation by acting on farnesyl diphosphate and its derivative geranylgeranyl diphosphate, two precursors for the addition of isoprenoid anchors to membrane proteins.  Has a lower activity towards phosphatidic acid (PA), but through phosphatidic acid dephosphorylation may participate in the biosynthesis of phospholipids and triacylglycerols.  May also act on ceramide-1-P, lysophosphatidic acid (LPA) and sphing-4-enine 1-phosphate/sphingosine-1-phosphate.
What are the official names of this protein?
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6, Phospholipid phosphatase 6.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope. Nucleus inner membrane.
Protein: KDSA_SALCH
Sequence: MKQKVVNIGDIKVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKVITDVHEASQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFHEGGNDKVILCDRGANFGYDNLVVDMLGFSVMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRGQVTELARAGMAVGLAGLFLESHPDPANAKCDGPSALPLAKLEQFLTQIKAIDDLVKSFDELDTEN
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT25_ASPCL
Sequence: MGKYNLTALRVHQTALQQHAAGKIRAPPKWIDVVADIPPAQVLVRNQAAQHQLVRQRLKTVPGASKPQVAFEVQEKRIKSKKASRMFLPTEIKYEEDQLRREFFRDHPWELARPRVVVESSGRDFERYDWSRLQQPGKRLDGESVVQRQLWLLNNVPDMTRSAAYDIARREFYRLRLQEDIERRVAAEEAEATGATFGRSLLEVGMELENQQYERWKEWAKSEAQLQDQKTAAFVGAPEIAAHDEAVEPIEEKSALPL
What are the official names of this protein?
37S ribosomal protein S25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: APT_PSEA7
Sequence: MIFDEFTLKSQIRAVPDFPKAGVVFRDITPLFQSPRALRMTVDSFVQRYIEADFSHIGAMDARGFLIGSAVAYALNKPLILFRKQGKLPADVLAEAYQTEYGEAFLEVHADSLCEGDSVLIFDDLIATGGTLLAAASLVRRLGARVFEAAAIIDLPELGGSTRLQDAGIATFSLTAFALDER
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTRP_BACSU
Sequence: MVEQTKDQLSAFHYHMLDFLLTKSEKVTFTDSFIWLTSAIQTYFSTLCVSLTPSPSDFVTKLADGEARFSASKINASCYLIEDGSGRRFHLACRQDEEIPEGLPDVVASFLNQSMKQERLYNKTIYQKKIYKMTELFHSLLDQTDVLKQLLESLTSTFSLFEFSLFISHDQDQCLGIPAKELYMEGEKSDSFALKVYLSGDILRKNESVAYIPIKGQQGTYGVLKAEGTGDSFLTDACLDEMSLLANAAGKAFENAQLYEQSKASIANLELINETSRRLNQRLTLTDTMNDLAVRMAESFQAEEVGFFHIDHFENLTLLPGSTAFFKEAKPSDFYNELKEKLYEGEKGVFIGNGQSVFGKAGYGSLMAAPMIQNDRLLGFAVLLKQELYAFTFEMYKLFQALIHHATLAVTNSMLRDRLEHLVKTDQLTELYSRAYLDEKIQYSMKIHQKGVFILVDIDNFKNVNDTYGHQTGDEILIQVASVIKSNIRKHDVGARWGGEELAIYLPNVPVAVGKRITERLVYAVRKNTKPEVTISCGISCWTTETKKSLKELVHEADEALYSAKRSGKNRLMIHDSIK
What are the official names of this protein?
Uncharacterized protein YtrP.
Protein: NDUS3_ORYSJ
Sequence: MDNQFIFQYSWEILPKKWVHKMKRSEHGNRFYTNTDYLFPLLCFLKWHTYTRVQVLIDICGVDYPSRKRRFEVVYNLLSTRYNSRIRVQTSADEVTRISSVVSLFPSAGWWEREVWDMFGVSFINHPDLRRILTDYGFEGHPLRKDFPLSGYVEVRYDDPEKRVVSEPIEMTQEFRYFDFASPWEQRSDG
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, NADH dehydrogenase subunit 9.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: MRAZ_FRASN
Sequence: MFLGSHTPRLDDKGRLTLPAKFREELEGGLVITKGQERCLYVFPLAEFTRISESLRTAPVTAKALRDYSRVFFSSASDDVPDRQGRITIPPPLRAYAGLVRECVVNGANTRVEIWDSQRWDTYLADQEETFAEMSEEVLPGVI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.