PharMolix/UniProtQA huggingface dataset:
Protein: SECA1_CHLCH
Sequence: MLKIFEKLFGSKHEKDVKKIQPTIQRINELQRALASLSDEQLRQKGRELKQKVRGVLEPMELEQQKLFHQLDSPNISLDEAESVNNKLDDLAVAYETATASVLEEILPDTFALVKETCARLKGHTYNVMGRQFVWNMVPYDVQLIGGIVLHSGKIAEMQTGEGKTLVSTLPTFLNALTGRGVHVVTVNDYLAQRDKEWMEPLFAFHNLSVGVILTSMHPALRRAQYLCDITYGTNNELGFDYLRDNMANTPEEMVQRKFYYAIVDEVDSVLIDEARTPLIISGPVPNADNSKFQEIKPWIEQLVRAQQQQIAAWLGDAETRMKTNATDPEAGLALLRVKRGQPKNSRFIKMLSQQGVAKLVQITENEYLKDNSSRMHEVDDALFYAVDEKANTIDLTDKGRDFLSKLSHQDSDIFLLPDVGTEIATIESNAALSTNDKIQHKDALYRLFSDRSERLHNISQLLKAYSLFERDDEYVVQNGQVMIVDEFTGRILPGRRYSDGLHQAIEAKENVKIEGETQTMATITIQNFFRLYKKLAGMTGTAETEASEFYEIYKLDVVVIPTNASVVRKDMDDLVYKTRREKYNAIAQKVEELQKRGQPVLVGTTSVEVSETLSRMLRTRRIAHNVLNAKQNDREAEIVAEAGQKGTVTIATNMAGRGTDIKLGDGVRELGGLYILGSERHESRRIDRQLRGRAGRQGDPGESVFYVSLEDELMRLFGSDRVIAVMDRLGHEEGDVIEHSMITKSIERAQKKVEEQNFAIRKRLLEYDDVLNQQREVIYSRRKNGLLKERLTSDILDLLKDYSDTIVKKYHKDFDTAGLEEQLMRDLSIEFQLDRATFEREGIDAVVDKVYETALTFYRRKEESLPADIMCQIEKYAVLTVIDQRWREHLREIDSLREGINLRAYGQKDPLIEYKQEAFRLFITLLKEIEAETLSLAFKLFPIDPEEQQQIEERQRQSAIRQEKLVAQHDVAESFVGLNDDDEPLPAQPITTEQKPGRNDLCPCGSGKKYKACCGQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CPET_MICDP
Sequence: MTSSLPKIPDTVSPNLITLARWMAGDFSNYQQAFENSKDYAHIHVFFRPLPFEFFSGIGLYSEQVYDYDLWRPYRQGVHRLIDKGDEIYIENYSLKQALYYAGAARDLNILKTITPNCIERRYHCSMIFKREGDKFIGGVEPGNLCLIEKNGCQTYLDSYVEITETTWVSLDKGMDVNTHQQVWGSTFGPLRFEKRESFADEIPNIL
What is the function of this protein?
May attach a phycoerythrobiline (PEB) chromophore to apo-biliprotein(s).
What are the official names of this protein?
Probable phycoerythrobilin lyase CpeT.
What is the protein family that this protein belongs to?
Belongs to the CpcT/CpeT biliprotein lyase family.
Protein: GPDA_DESRM
Sequence: MAKVAMIGAGSWATALAQVLAQNNNSVLLWARRPELAQLINEGENKRYLPGVQLHPSLSADTDLEKVLHQAEAVVFGVPSHGFRELLQKSRPYIKSDAFIINVAKGLEESTLLRLSEVCASEFGEAVLSRYAVLSGPSHAEEVGLNIPTAVVAAAQEIRMAEYVQDLFMSQDFRVYTNPDLVGVELGGALKNIIALGTGIADGLGFGDNTKAAMMTRGLAEITRLGYSMGANLLTFAGLAGVGDLIVTCTSMHSRNRRCGIAIGQGKTIQEAVESVNMVVEGIRTTHVAWELAKNQGVEMPITEQTYQVLFHGLSPRDAVLNLMGRGKKNEVEELSLATYNIIQ
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GOLM1_HUMAN
Sequence: MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL
What is the function of this protein?
Unknown.  Cellular response protein to viral infection.
What are the official names of this protein?
Golgi membrane protein 1, Golgi membrane protein GP73, Golgi phosphoprotein 2.
What is the protein family that this protein belongs to?
Belongs to the GOLM family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein. Note=Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption.
Protein: TF2H1_HUMAN
Sequence: MATSSEEVLLIVKKVRQKKQDGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSNESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATDSSSTSNHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAENVPHNMTEKEFWTRFFQSHYFHRDRLNTGSKDLFAECAKIDEKGLKTMVSLGVKNPLLDLTALEDKPLDEGYGISSVPSASNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQEAQNEQTSEPSNMDGNSGDADCFQPAVKRAKLQESIEYEDLGKNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIINSFQSIRQEMEAYTPKLTQVLSSSAASSTITALSPGGALMQGGTQQAINQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQYLSTNLVSHIEEMLQTAYNKLHTWQSRRLMKKT
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
What are the official names of this protein?
General transcription factor IIH subunit 1, Basic transcription factor 2 62 kDa subunit, BTF2 p62, General transcription factor IIH polypeptide 1, TFIIH basal transcription factor complex p62 subunit.
What is the protein family that this protein belongs to?
Belongs to the TFB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FUS_PI2H
Sequence: MHHLHPMIVCIFVMYTGIVGSDAIAGDQLLNIGVIQSKIRSLMYYTDGGASFIVVKLLPNLPPSNGTCNITSLDAYNVTLFKLLTPLIENLSKISTVTDTKTRQKRFAGVVVGLAALGVATAAQITAAVAIVKANANAAAINNLASSIQSTNKAVSDVIDASRTIATAVQAIQDHINGAIVNGITSASCRAHDALIGSILNLYLTELTTIFHNQITNPALTPLSIQALRILLGSTLPIVIESKLNTNLNTAELLSSGLLTGQIISISPMYMQMLIQINVPTFIMQPGAKVIDLIAISANHKLQEVVVQVPNRILEYANELQNYPANDCVVTPNSVFCRYNEGSPIPESQYQCLRGNLNSCTFTPIIGNFLKRFAFANGVLYANCKSLLCRCADPPHVVSQDDTQGISIIDIKRCSEMMLDTFSFRITSTFNATYVTDFSMINANIVHLSPLDLSNQINSINKSLKSAEDWIADSNFFANQARTAKTLYSLSAIALILSVITLVVVGLLIAYIIKLVSQIHQFRSLAATTMFHRENPAFFSKNNHGNIYGIS
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with HN at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: YP148_YEAST
Sequence: MSGYFSGFSLNKITDSIATAAHKTQDTLNNALANANVNLNDPQTRLSIKSRTRFVQESLGTVSDISKLPPQYQFLEKKSDSLEKVCKRILLVSKTFEVEGYDYPPNLTESISDWWSLNKDGWFGSKKSESSTKKKGSNHDDAFLPRSFAQAISKAAVDCECEFQNLEHNEKAELKKKKESIKTAQTTEAQGADHNEEDEEDEEDEEDDEDLSNLIKVFDSWSTCYKNIDEGKAEMDSMMVKEFNKKLETLINQDFKKVHDLRKKVEESRLKFDTMRYEVKAKEAELEAKKAEATGEAHSKDVSAKDISANTTTSFDETPSTEDEKPKSEGAEEESKKEANEPTVDDVADRKEDLKSNKVNDEPPIEESEDNKLLEKLEDEFVSNTTAAVETMEEITDSSEILGLIKLFQNFQLVYFRQCVQEVEANLKVLNGLEI
What are the official names of this protein?
Uncharacterized protein YPR148C.
What are the subcellular locations of this protein?
Cytoplasm. Note=Cytoplasmic punctate structures.
Protein: Y543_LEPBJ
Sequence: MSGHSKWATIKRKKDAIDSKRGAIFTRVGKEITVAAKMGGGDPEGNPRLRLAILKAKSVNMPKDNIERAIKKGTGELEGVVYEECLYECFGPAGIAIMVSAVTDKKSRTTPEIKSILTKLGGSLATSGSVSRLFEKKGVIVLESSQIGEDKLVDLAVGEGAEDVINEGEVYRVITTPDDYESVLHALNEKGLKSEESEIRYIALVSSEIADKEVAKKVMKLIEQLDGHDDVTSVTSNFELAASLEKEFE
What are the official names of this protein?
Probable transcriptional regulatory protein LBJ_0543.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_SALPK
Sequence: MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHLGRLLQFKAWGLPVSDRVTLCDSPQAVLDFYHNVEKDRPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETRPIVFPTHCPVCGSDVERVEGEAVTRCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAGKLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAAGLAAYFGTLEALQAATIDELQKVPDVGIVVATHVFNFFAEESNRDVIVQLLAEGVHWPAPVVINVQEIDSPFAGKTVVLTGSLSQMSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGINVIDEAEMIRLLGA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: HPRK_BACAC
Sequence: MPKVRTKDLIEQFQLELISGEEGIHRPIDTSDLSRPGIEMAGFFTYYPADRVQLLGKTELTFFDTLTSDQKQERMKALCTEETPCIIVTRNQDVPDELLQASRESGMPLLRSSQTTTRLSSRLTNYLEGKLAPTTAVHGVLVDIYGVGVLITGQSGVGKSETALELVKRGHRLVADDSVEIRQEDEDMLVGSSPDLIEHLLEIRGLGIINVMTLFGAGAVRNYKRITLVINLEIWDQKKNYDRLGLDEEKMKIIDTELTKITLPVRPGRNLAVIIEVAAMNFRLKRMGVNAAQQFSERLMSAIELGNQE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue.  Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: CYC2_ARATH
Sequence: MASFDEAPPGNPKAGEKIFRTKCAQCHTVEKGAGHKQGPNLNGLFGRQSGTTPGYSYSAANKSMAVNWEEKTLYDYLLNPKKYIPGTKMVFPGLKKPQDRADLIAYLKEGTA
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
What are the official names of this protein?
Cytochrome c-2, Cytochrome c At4g10040.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: DXS_HAEIE
Sequence: MTNNMNNYPLLSLINSPEDLRLLNKDQLPQLCQELRAYLLESVSQTSGHLASGLGTVELTVALHYVYKTPFDQLIWDVGHQAYPHKILTGRREQMSTIRQKDGIHPFPWREESEFDVLSVGHSSTSISAGLGIAVAAERENAGRKTVCVIGDGAITAGMAFEALNHAGALHTDMLVILNDNEMSISENVGALNNHLARIFSGSLYSTLRDGSKKILDKVPPIKNFMKKTEEHMKGVMFSPESTLFEELGFNYIGPVDGHNIDELVAMLTNMRNLKGPQFLHIKTKKGKGYAPAEKDPIGFHGVPKFDPISGELPKNNSKPTYSKIFGDWLCEMAEKDAKIIGITPAMREGSGMVEFSQRFPKQYFDVAIAEQHAVTFATGLAIGGYKPVVAIYSTFLQRAYDQLIHDVAIQNLPVLFAIDRAGIVGADGATHQGAFDISFMRCIPNMIIMTPSDENECRQMLYTGYQCGKPAAVRYPRGNAVGVKLTPLEMLPIGKSRLIRKGQKIAILNFGTLLPSALELSEKLNATVVDMRFVKPIDIEMINVLAQTHDYLVTLEENAIQGGAGSAVAEVLNSSGKSTALLQLGLPDYFIPQATQQEALADLGLDTKGIEEKILNFIAKQGNL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: DDDQ_RUELI
Sequence: MTLENVLEAARHLHQTLPALSEFGNWPTDLTATGLQPRAIPATPLVQALDQPGSPRTTGLVQAIRSAAHLAHWKRTYTEAEVGADFRNRYGYFELFGPTGHFHSTQLRGYVAYWGAGLDYDWHSHQAEELYLTLAGGAVFKVDGERAFVGAEGTRLHASWQSHAMSTGDQPILTFVLWRGEGLNALPRMDAA
What is the function of this protein?
Able to cleave dimethylsulfonioproprionate (DMSP) in vitro, releasing dimethyl sulfide (DMS).  DMS is the principal form by which sulfur is transported from oceans to the atmosphere (PubMed:24395783, PubMed:24967457).  The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethylsulfonioproprionate lyase in vivo: the very low activity with DMSP as substrate suggests that DMSP is not its native substrate (PubMed:24760823).
What are the official names of this protein?
Dimethylsulfonioproprionate lyase DddQ, DMSP lyase.
What is the protein family that this protein belongs to?
Belongs to the non-heme iron-dependent dioxygenase family.
Protein: GATB_PSEA8
Sequence: MQWETVIGLEIHAQLATQSKIFSGSSTAFGAAPNTQASLVDLAMPGTLPVLNEEAVRMACLFGLAIDARIDRQNVFARKNYFYPDLPKGYQTSQMDHPIVGKGHLDITLEDGTTKRIGITRAHLEEDAGKSLHEDFQGMSGIDLNRAGTPLLEIVSEPDIRSAKEAVAYVKAIHALVRYLGICDGNMAEGSLRCDCNVSVRPKGQAEFGTRAEIKNVNSFRFIEKAINHEIQRQIELIEDGGKVVQETRLYDPNKDETRSMRGKEEANDYRYFPCPDLLPVVIEPEYLAKLREQLPELPVQKRERFESQYGLSAYDASVLSASREMADYFEKVQGICGDAKLAANWVMVELGSLLNKDGLEIEQSPVSAEQLGGMILRIKDNTISGKLAKMVFEAMANGEGSADQIIEAKGLKQVTDSGAIEKMLDEVLAANAEQVEQYRAADEAKRGKMFGFFVGQAMKASKGKANPQQVNELLKKKLEA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PDXS_DEHMB
Sequence: METGTFKVKSGLAQMLKGGVIMDVTTPEQAKIAEEAGACAVMALERVPSDIRAAGGVARMADPTIIEQIMKVVSIPVMAKCRIGHFVEAQILESMGVDYIDESEVLTPADENFHVWKHDFKVPFVCGCRDLGEALRRIGEGAAMIRTKGEAGTGNIVEAVRHMRSVMGSVRRVQSMSPDELSAYAKEINAPLELVLELHKTGKLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSSNPSAMAKAVVKAVTHYKDAQILAEISKGLGDAMPGLDIKQIDPDKLISQRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: TRUB_SERP5
Sequence: MSRPRRRGRDIHGVLLLDKPQGLSSNDALQKVKRLYNANRAGHTGALDPLATGMLPICLGEATKFSQFLLDSDKRYRVIARLGQRTDTSDADGQIVQERPVSFTQAQLDAALDSFRGDIKQVPSMYSALKYQGKKLYEYARQGIEVPREARSITVYELQFIRWEGDELELEIHCSKGTYIRTITDDLGELLGCGAHVIYLRRLQVATYPTERMVTLEQLNELLEQAHRQEIAPAELLDPLLMPMDSPVENYPEVNLLPVVAGYVKQGQPVQVAGAPASGMVRITEGEERKFIGVGDIADDGRVAPRRLVVEYFD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RL25_GEOSM
Sequence: MSKQVLKVELREKTGKGICRRLRAAGRVPAVVYGKGITPVSISLGQKELSEAIAGEGGRNHILTLECAGELNGANVIVADLLRDSLRNQPRHVDLHKINLADKVKVHVKLNLVGTPAGVKAGGFLDFAMHEIEVECLPVHIPAHINVDVTELLIGHSVHVGEIAAPIGTAILSDPKAAVVSILGRKAVAEEEAAPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: YIHY_ECOUT
Sequence: MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMN_PSEAE
Sequence: MTTTTAGKVNLLGLTQPQLEQFFESIGEKRFRAGQVMKWIHHFGVDDFDAMTNVGKALREKLKASAEIRGPEIVSQDISADGTRKWVVRVASGSCVETVYIPQGGRGTLCVSSQAGCALDCSFCSTGKQGFNSDLTAAEVIGQVWIANKSFGTVPAKIDRAITNVVMMGMGEPLLNFDNVVAAMNIMMDDLGYGISKRKVTLSTSGVVPMIDKLGEVIDVSLALSLHAPNDELRNKLVPINKKYPLGMLLDACRRYISRLGEKRVLTVEYTLLKDVNDQPEHAEQMIALLKDTPCKINLIPFNPFPHSGYERPSNNAIRRFQDMLHKGGFNVTVRTTRGDDIDAACGQLVGQVMDRTRRSERYIAVRQLAESESAANRN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GOT1A_BOVIN
Sequence: MISITEWQKIGVGTTGFGIFFILFGMLLYFDSVLLAFGNLLFLTGLSLIIGLRRTFSFFFQRHKFKGTSFFLGGVVIVLLRWPLLGMCLETYGFFSLFRGFFPVAFGFLGSASNIPFLSALFQRLQGTSSMV
What is the function of this protein?
May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
What are the official names of this protein?
Vesicle transport protein GOT1A, Golgi transport 1 homolog A.
What is the protein family that this protein belongs to?
Belongs to the GOT1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: FTSY_NEIGO
Sequence: MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAGEAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLITGDMGMEATEYLMKDVRGRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARIDIVLADTAGRLPTQLHLMEEIKKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGIDDLRPFDARAFVDRLLD
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).  Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: FOX3_ARATH
Sequence: MKALFSVLCLVLLVSILRAAVTKPDSGIFTGCLRNRTSLENPITDAIFTSRNTTTFLSSYVSYTKNKRYSSLNYQKLVAIVAAKHVSHVQATVVCAKANGIQLRIRSGGHDYEGLSYTSSVPFVILDMYNLRSITVDVSSKKAWVQAGATLGELYTKINEASQTLAFPAGVCPTVGVGGHITGGGFGNLMRKFGITVDHVIDAQLIGVNGKLLDRATMGEDLFWAIRGGGGASFGVILSWKINLVEVPKILTVFKVSKTLEQGGTDVLYKWQLVATKVPEDLFIRAWPQIVKGTKLGERTIGVVFFAQFLGPTDKLMEIMSQSLPELGLRREDCHEMSWFNTTLFWANYPVGTPTRVLLDRPSTPGEFFKSKSDNIKKPIPKEGLEKIWKTMLKFNFVWIEFNPYGGVMDRIPATATAFPHRKGNLFNLQYSTIWLDAKETENKLTMMKELYEVAGPYVSSNPREALFNFRDFDIGINPSGLNVDEAKIYGYKYFLGNLKRLMDVKAKCDPDNFFKNEQSILPARVM
What is the function of this protein?
Probable flavin-dependent oxidoreductase.
What are the official names of this protein?
Berberine bridge enzyme-like 5, AtBBE-like 5, Flavin-dependent oxidoreductase FOX3.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: SYDND_PSEAB
Sequence: MMRSHYCGQLNESLDGQEVTLCGWVHRRRDHGGVIFLDVRDREGLAQVVFDPDRAETFAKADRVRSEFVVKITGKVRLRPEGARNPNMASGSIEVLGYELEVLNQAETPPFPLDEYSDVGEETRLRYRFIDLRRPEMAAKLKLRARITSSIRRYLDDNGFLDVETPILGRPTPEGARDYLVPSRTYPGHFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQIDIETSFLDESDIIGITEKMVRQLFKEVLDVEFDEFPHMPFEEAMRRYGSDKPDLRIPLELVDVADQLKEVEFKVFSGPANDPKGRVAALRVPGAASMPRSQIDDYTKFVGIYGAKGLAYIKVNERAKGVEGLQSPIVKFIPEANLNVILDRVGAVDGDIVFFGADKAKIVCDALGALRIKVGHDLKLLTREWAPMWVVDFPMFEENDDGSLSALHHPFTSPKCTPAELEANPGAALSRAYDMVLNGTELGGGSIRIHDKSMQQAVFRVLGIDEAEQEEKFGFLLDALKYGAPPHGGLAFGLDRLVMLMTGASSIREVIAFPKTQSAGDVMTQAPGSVDGKALRELHIRLREQPKAE
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.