PharMolix/UniProtQA huggingface dataset:
Protein: RS17_CLONN
Sequence: MERSNRKTRIGRVVSDKMEKTIVVAVEGKVRHPLYGKTINRSKKFKVHDENNEARINDRVLIMETRPLSKDKRWRLVQIVEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SPI2_MYXVL
Sequence: MELFKHFLQSTASDVFVSPVSISAVLAVLLEGAKGRTAAQLRLALEPRYSHLDKVTVASRVYGDWRLDIKPKFMQAVRDRFELVNFNHSPEKIKDDINRWVAARTNNKILNAVNSISPDTKLLIVAAIYFEVAWRNQFVPDFTIEGEFWVTKDVSKTVRMMTLSDDFRFVDVRNEGIKMIELPYEYGYSMLVIIPDDLEQVERHLSLMKVISWLKMSTLRYVHLSFPKFKMETSYTLNEALATSGVTDIFAHPNFEDMTDDKNVAVSDIFHKAYIEVTEFGTTAASCTYGCVTDFGGTMDPVVLKVNKPFIFIIKHDDTFSLLFLGRVTSPNY
What is the function of this protein?
Weak inhibitor of the interleukin-1-beta converting enzyme (ICE) and of granzyme B.  Does not form a stable complex with ICE, but can for a stable complex with granzyme B.
What are the official names of this protein?
Serine proteinase inhibitor 2, Serp-2, Serpin-2.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Poxviruses subfamily.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: DNAA_BURP6
Sequence: MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGRISDLARDFWNAPIEVQFVLDPKAGQRSPAGATPLAPRAPLPSANPAPVAPGPASAPAVDAHAPAPAGMNAATAAAVAAAQAAQAAQANAAALNADEAADLDLPSLTAHEAAAGRRTWRPGAANANSEAADSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLYGGVGLGKTHLIHAIGNQLLLDKPGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKSRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEGVSLSEDVAFFVAKHLRSNVRELEGALRKILAYSKFHGREITIELTKEALKDLLTVQNRQISVENIQKTVADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERGKDAQLNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_DESVM
Sequence: MSIAYNKIAVRVRLGALRRNFETLRRMSPAAMPVIKSDAYGHGLLPVARTLEAAGADAFAAGTVGECAQLRDGGIPGRIVALLGATDAADAECCVARSIVPAVYSADQLEMLAGRAAPGQQVDIALKFDTGMARLGFSEADLPALLDRLHARPMLRPVLVMSHLAVSDDPSRSDFTRQQGEAFGRILAGVRADWPAAQGSLANSAALLAHPELHFDVQRPGIALYGANPLRGTAQEHLGDGLQPAMDVAAPILQVHPLPAGRSISYGRTFTAPRDMTVAIVATGYADAYSRGLSGKGAMTVHGRRVPILGRVCMQMTAVDVTDVPGVAAGDDAYLLGGPGEALTPDELADLWGTISYEVLCLLGMNPRTHRE
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PHYD1_CAEEL
Sequence: MWDLREKFERDGFVVVENVFNDQEIDEMKKSISKIVNDMDLAEHPKSVFSTYDEDKHAADSYFLNSSDKIRFFFEEGAVDKDGELTVPKDKALNKIGHGLHFLDPTFEKMTFNSKIQNIFKEIGYQEPGVVQSMYIFKQPKIGGAVTDHVDSTFLRVDPIDHLTGVWIAIDEASVENGCLSFIPGSHKDTSSANYRFVRTHDTSGGALLKFIGTRPTYDQSKFQHVPISKGSLILIHGLVVHKSEANTSEKSRHAYTIHVMERKNTKWSEQNWLQETENYKFPDLYKD
What is the function of this protein?
Has alpha-ketoglutarate-dependent dioxygenase activity.  Does not show detectable activity towards fatty acid CoA thioesters.  Is not expected to be active with phytanoyl CoA (By similarity).
What are the official names of this protein?
Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the PhyH family. PHYHD1 subfamily.
Protein: RS18_STRS7
Sequence: MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RS3_DICTD
Sequence: MGQKTHPYGFRLGITKDWKSHWYAERSDYSSLLHEDWAIRNYIKKNYYQAGISLIEIERKAANRVDITIHTARPGMLIGRGGSEIENIRKNLVKLTNKSVFVNVQEVKNPELDAQLVAENIATQIEKRINYKRAMKQAINRALRAGAKGVKVMCSGRLNGAEIARSEWFREGRIPLQTLTADIDYGFAEAFTISGVIGVKVWIYKGDVPELHKEPIQELPEKAVPKKIEDEDLYEKDEVNYDVDA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: Y1675_ARCFU
Sequence: MKAIYALLAVVALALVAVSLFSQSDSMEGWYSYQEGKKLSEEQKKEMFVFIGTSECGVCKRFKEFFRSNQSAMEFIRKNYIPVYVDAMREKTPVRVTFVPVFCTGFDGNLSCFSTAFPEELMMLLEK
What are the official names of this protein?
Uncharacterized protein AF_1675.
Protein: OMPD_CITK8
Sequence: MKLKLVAVAVTTLLAAGAVNAAEVYNKDGNKLDLYGKVHAQHYFSDDTGSDGDKTYARLGFKGETQINDQLTGFGQWEYEFKGNRSENQGSDKDKTRLAFAGLKFAEFGSFDYGRNYGVAYDIGAWTDVLPEFGGDTWTQTDVFMTGRTTGVATYRNTDFFGLVEGLNFAAQYQGKNDRDGVQEANGDGFGLSATYEYEGFGVGATYAKSDRTDKQVNAASNFNANGKNAEVWAAGLKYDANDIYLAATYSETLNMTTFGDDHIANKTQNFEAVAQYQFDFGLRPSIAYLKSKGKDIGSWGDQDLVEYIDLGATYYFNKNMSTFVDYKINLLDDTNFTKDARVSTDNVVAVGLNYQF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane porin protein OmpD.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SPEE_HELPH
Sequence: MWITQEITPYLRKEYTIEAKLLDVRSEHNILEIFKSKDFGEIAMLNCQLLFKNFLHIESELLAHMGGCTKKELKEVLIVDGFDLELAHQLFKYDTHIDFVQADEKILDSFISFFPHFHEVKNNKNFTHAKQLLDLDIKKYDLILCLQEPDIHKMDGLKRMLKEDGVFISVAKHPLLEHVSMQNALKNMGGVFSVAMPFVAPLRILSNKGYIYASFKTHPLKDLMTPKIEALTSMRYYNEDIHRAAFALPKNLQEVFKDNIKS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM3_HHV6U
Sequence: MLRTCDITHIKNNYEAIIWKGERDCSTISTKYPNSAIFYKKRFIMLTPELGFAHSYNQQVKPLYTFCEKQRHLKNRKPLTILPSLSHKLQEMKFLPASDKSFESQYTEFLESFKILYREPLFLQIDGFIKDFRKWIKGEFNDFGDTRKIQLEPFQKNILIHVIFFIAVTKLPALANRVINYLTHVFDIEFVNESTLNTLKQKTNVFLVPRRHGKTWFIVPIISFLLKNIEGISIGYVAHQKHVSHFVMKEVEFKCRRMFPEKTITCLDNVITIDHQNIKSTALFASCYNTHQSIRGQSFNLLIVDESHFIKKDAFSTILGFLPQASTKILFISSTNSGNHSTSFLMKLNNSPFEMLSVVSYVCEDHAHMLNERGNATACSCYRLHKPKFISINAEVKKTANLFLEGAFIHEIMGGATCNVINDVLITEQGQTEFEFFRYSTINKNLIPFLGKDLYVYLDPAYTGNRRASGTGIAAIGTYLDQYIVYGMEHYFLESLMTSSDTAIAECAAHMILSILDLHPFFTEVKIIIEGNSNQASAVKIACIIKENITANKSIQVTFFHTPDQNQIAQPFYLLGKEKKLAVEFFISNFNSGNIKASQELISFTIKITYDPVEYALEQIRNIHQISVNNYITYSAKKQACSDDLIIAIIMAIYVCSGNSSASFREI
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 3, Terminase large subunit.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM3 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Responsible for the nuclear localization of the two others subunits TRM1 and TRM2.
Protein: RL17_HAEDU
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMASALIGHEIIKTTLPKAKELRRVVEPLITLAKEDSVANRRLAFARTRNIETVAKLFNELGPRFAQRAGGYTRILKCGFRAGDNAPMAYIELVDRPEVAEVTAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: TYDC2_PAPSO
Sequence: MGSLNTEDVLENSSAFGVTNPLDPEEFRRQGHMIIDFLADYYRDVEKYPVRSQVEPGYLRKRLPETAPYNPESIETILQDVTTEIIPGLTHWQSPNYYAYFPSSGSVAGFLGEMLSTGFNVVGFNWMSSPAATELESVVMDWFGKMLNLPESFLFSGSGGGVLQGTSCEAILCTLTAARDRKLNKIGREHIGRLVVYGSDQTHCALQKAAQVAGINPKNFRAIKTFKENSFGLSAATLREVILEDIEAGLIPLFVCPTVGTTSSTAVDPISPICEVAKEYEMWVHVDAAYAGSACICPEFRHFIDGVEEADSFSLNAHKWFFTTLDCCCLWVKDPSALVKALSTNPEYLRNKATESRQVVDYKDWQIALSRRFRSLKLWMVLRSYGVTNLRNFLRSHVKMAKTFEGLICMDGRFEITVPRTFAMVCFRLLPPKTIKVYDNGVHQNGNGVVPLRDENENLVLANKLNQVYLETVNATGSVYMTHAVVGGVYMIRFAVGSTLTEERHVIYAWKILQEHADLILGKFSEADFSS
What is the function of this protein?
Marginally higher substrate specificity for L-DOPA over L-tyrosine.
What are the official names of this protein?
Tyrosine/DOPA decarboxylase 2.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: RL21_RICRS
Sequence: MFAVIKAGGKQYKVDRNSIIKVEKIDGELGSKIQFDQILMIGEYSKPSFIGTPIVKGAVVTAEITNQLKDNKIIVFKKKRRKNYRRKAGHRQELTELKILDITKQ
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: OLA1_DROME
Sequence: MPPKKHDEPERKPLIGRIGTNLRIGIVGVPNVGKSTFFNVLTQSAAPAENFPFCTIKPNESRVPVPDERFDYLVEYHKPASVVPAYLNVVDIAGLVKGAAEGQGLGNDFLSHISACDAIFHLCRAFEDPDVTHVEGEVDPVRDLEIISEELRLKDEENLLKNLDKLEKVVARGGDKKLKPEYDSMLKIKDILIDQKRHLRFEDWNAHDIEALNKYLFLTSKPVIYLVNLSDKDFIRKKNKWLPKIKEWIDKNDPGALLIPFSGAFEHQLTEKDELERKAYETETKCKSMLEKIVVTGYKGLQLEYFFTAGPDEVKAWTIQKGTKAPQAAGRIHTDFEKGFIMAEVMHFEDFKAEGSEANAKAAGKYRQQGRNYTVEDGDIIFFKFNAGAGLKDAKKK
What is the function of this protein?
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency.  Has lower affinity for GTP.
What are the official names of this protein?
Obg-like ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_PROM2
Sequence: MKEIYLIGLGNPGKKFLNSRHNIGFLLLEYFSKKYNSNFLFKDKLKSSYSEFQIDNSSYRLFLPNTFMNNSGYAVRAIVDWYKINLDQIFIIVDDKDLPLGKIRFRRKGSSGGHNGLKSIIEQLQTQKFKRIRIGIGSPPPIKGEKNFNTISHVLGNISLEEKSILDKVFRRVIESLEKLNTKKEEYIINELNSFDKDQH
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUHB_PASMU
Sequence: MNPMLNIAIRAARKAGNVIAKGYERRDDLQTTLKSTNDYVTNIDKASEEAIIEVIRKSYPDHTIITEESGALEGKDSDIQWVIDPLDGTTNFVKGLPHFSVSIAIRVKGRTEVGVVYDPIRNELFTAVRGEGAKINDMRLRVENKRDLAGTVLTTGFPFKQTRLMPMQFAMMNNLIQDCADFRRMGSAALDLCYVAAGRVDGYFEVGVKAWDIAAGDLIVREAGGLVCDFNGGHSYLTSGHLVAAAPRIVKEILNKIQPCLSDEFKK
What is the function of this protein?
Part of the processive rRNA transcription and antitermination complex (rrnTAC).  The complex forms an RNA-chaperone ring around the RNA exit tunnel of RNA polymerase (RNAP).  It supports rapid transcription and antitermination of rRNA operons, cotranscriptional rRNA folding, and annealing of distal rRNA regions to allow correct ribosome biogenesis.  This subunit may play a central role in organizing the structure.
What are the official names of this protein?
Nus factor SuhB, Inositol-1-monophosphatase, I-1-Pase, IMPase, Inositol-1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y269_RHOPA
Sequence: MSLSPSERPDTVDRKLLDILVCPVTKGPLEFDPARQELISRGAKLAYPIRDGIPIMLPEEARKLG
What are the official names of this protein?
UPF0434 protein RPA0269.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: GLYA_BUCBP
Sequence: MFIKNKTISNYDADVYRMMKQEYQRQENHIELIASENYVSSCVMEAQGSQLTNKYAEGYPGKRYYGGCDYVDAIEKIAIKRAKKLFNANYANVQPHSGSQANYAVYSALLKPNDIVLGMSLSHGGHLTHGSSVNFSGKLYKFISYGLDISGDIDYPQIRKLAHRYKPKMIVGGFSAYSGICNWKLLREIADEINSYLFVDMAHISGLVAAGLYPNPLKYAHVVTSTTHKTLSGPRGGLILAKGDNVSLFKKLNSSVFPGCQGGPLMHVIAAKAIAFKEAMEPEFKDYQYQVIKNAQEMAKTFISRGYKVVSGKTFNHLLLLDLSNKNITGKRADILLHSANIIVNKNSIPNDLLSPFITSGIRIGTPAITRRGFTELESRQVSNWICDILDNFNNIEISAKVKQKVLNLCSLFPVYK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_TOLAT
Sequence: MKQLTPRQAEVLALIRSAVQQTGMPPTRAEIASELGFKSANAAEEHLKALARKGVIRMMPGTSRGIQLLTDEPEEDEGLPLIGRVAAGEPILAQQHIETHYQIDGSLFHPRADFLLRVHGMSMKNIGILDGDLLAVHKTTQANNGQVVVARVGDDEVTVKRFERKGHIVQLLPENEELQPIVVDLTQENLSIEGLAVGVIRNGNWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MNMA_STAAW
Sequence: MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKIEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP2DJ_CALJA
Sequence: MGLDALVPLAVTVAIFVLLVDLMHRRQRWAARYPPGPMPLPGLGNLLHVDFQNTPNSFNQLRRRFGDVFSLQLAWTPVVVLNGLEAVREALVTRGEDTADRPPVPITEMLGFGPHSQGLFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEATYLCAAFADHAGRPFRPNGLLDKAVSNVIASLTCRRRFEYNDPCLLRLLDLTMEGLKEESGLLREVLNAIPVLLRIPGLAGKVLRSQKAFLAQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKTKGNPESSFNDENLHLVVADLFSAGMVTTSITLAWGLLLMILHPDVQRRVQQEIDDVIGRVRRPEMGDQTYMPYTTAVIHEVQRFADIVPLGVTHMTSRDIEVQGFLIPKGTTLFTNLSSVLKDEANWEKPFRFHPEHFLDAQGRFVKPEAFLPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQPRPSPHGVFAFLVTPSPYELCAVPR
What is the function of this protein?
Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes.
What are the official names of this protein?
Cytochrome P450 2D19, CYPIID19, Cytochrome P450 CM2D-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: METXA_MYCSS
Sequence: MKSPAVPALDLPAEGETGVVDIGPLTLESGAVIDDVSIAVQRWGELSPNRDNVVMVLHALTGDSHVTGPAGPDHPTPGWWDGVAGPGAPIDTDRWCAVSTNVLGGCRGSTGPSSIAPDGRPYGSRFPAVTIRDQVTADLAALEALGITEVAAVVGGSMGGARALEWIVGHPATVRSALILAVGARATADQIGTQSTQVAAIKADPDWCGGDYHDTGRVPSTGLAIARRFAHLTYRGEVELDDRFGNHAQGDESPTDGGRYAVQSYLEYQGAKLVERFDAGTYVTLTDALSSHDVGRGRGGVRAALQGCRVPTIVGGVTSDRLYPLRLQQELAELLPGCTGLDVVDSVYGHDGFLVETEAVGKLIRRTLELAER
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECI1_HUMAN
Sequence: MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVMKFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAIAQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEEKG
What is the function of this protein?
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.
What are the official names of this protein?
Enoyl-CoA delta isomerase 1, mitochondrial, 3,2-trans-enoyl-CoA isomerase, Delta(3),Delta(2)-enoyl-CoA isomerase, D3,D2-enoyl-CoA isomerase, Dodecenoyl-CoA isomerase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LEXA_BORPD
Sequence: MASKLTDRQQEILDLIRLTVSRTGFPPTRAEIARALGFRSPNAAEDHLKALARKGAIELTAGASRGIRLKDAGETIPPGPETAASALAGMADAVGRLLLPLVGRVAAGSPILAAEHVEREVGVDVDLFAQTPDYLLKVRGMSMRDAGILEGDLLAVKRAAEARNGQIVVARLGDEVTVKRLQRHQGRIELLPENPDFSPIVVDGTQEFALEGIAVGLIRTQALH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: PLYE_EMENI
Sequence: MYQPLLLLPLLLTSAFANPHDPHIHHSLEKRASFPIPSSKGSVTFSSPKTISGTFDGGMKTYGRGVKCTGQDEGGDEDAVFILKDGATLKNAIIGADQIEGVHCEGSCTIENVWWTDVCEDALSLKGSGSGTHKIIGGGARNADDKVIQHNSGGKVIIQDFTVQNFGKLYRACGNCKKQFKRTVKISGVKASSGKALVGINSNYGDTASIKGCATSVKEICVEYEGTNNNSKEPKKKSSGPSSYCKYSEPLSKC
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester.
What are the official names of this protein?
Pectate lyase E.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1174_STRP7
Sequence: MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLTGDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SP70585_1174.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MYCP2_MYCTU
Sequence: MASPLNRPGLRAAAASAALTLVALSANVPAAQAIPPPSVDPAMVPADARPGPDQPMRRSNSCSTPITVRNPDVAQLAPGFNLVNISKAWQYSTGNGVPVAVIDTGVSPNPRLPVVPGGDYIMGEDGLSDCDAHGTVVSSIIAAAPLGILPMPRAMPATAAFPPPAGPPPVTAAPAPPVEVPPPMPPPPPVTITQTVAPPPPPPEDAGAMAPSNGPPDPQTEDEPAVPPPPPGAPDGVVGVAPHATIISIRQSSRAFEPVNPSSAGPNSDEKVKAGTLDSVARAVVHAANMGAKVINISVTACLPAAAPGDQRVLGAALWYAATVKDAVIVAAAGNDGEAGCGNNPMYDPLDPSDPRDWHQVTVVSSPSWFSDYVLSVGAVDAYGAALDKSMSGPWVGVAAPGTHIMGLSPQGGGPVNAYPPSRPGEKNMPFWGTSFSAAYVSGVAALVRAKFPELTAYQVINRIVQSAHNPPAGVDNKLGYGLVDPVAALTFNIPSGDRMAPGAQSRVITPAAPPPPPDHRARNIAIGFVGAVATGVLAMAIGARLRRAR
What are the official names of this protein?
Mycosin-2, MycP2 protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Cell wall-associated.
Protein: HIS7_NITEU
Sequence: MLMRTAQVTRNTQETQITVTINLDGQGKAELDSGVPFLDHMLDQIARHGMFDLSVAAKGDLHVDAHHTVEDIGITLGQALNRAVADKKGLVRYGHAYVPLDEALSRVVIDLSGRPGLQFNTTFTRAVIGNFDVDLIQEFFQGFVNHAMVTLHIDNLTGKNAHHQAETIFKAFGRALRMAVTTDPRCDNLIPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_ECODH
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: ATPF_SHESW
Sequence: MSINATLLGQAISFALFVWFCIKFVWPPLMNAIEERQKKIADGLADAGRAAKDLELAQAKATEQLKEAKVTANEIIEQANKRKAQIVEEAKAEADAERAKIIAQGKAEIENERSRVKDDLRKQVAALAVLGAERILERSIDQAAHSDIVDKLVAEI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PUIA_WHEAT
Sequence: MKALFLIGLLALVASTAFAQYSEVVGSYDVAGGGGAQQCPVETKLNSCRNYLLDRCSTMKDFPVTWRWWKWWKGGCQELLGECCSRLGQMPPQCRCNIIQGSIQGDLGGIFGFQRDRASKVIQEAKNLPPRCNQGPPCNIPGTIGYYW
What is the function of this protein?
Acts as a membranotoxin, probably through its antibacterial and antifungal activities, contributing to the defense mechanism of the plant against predators.  Forms monovalent cation-selective ion channels in membranes.  Has antibacterial activity against the Gram-positive bacteria S. aureus and C. michiganensis, and the Gram-negative bacteria E. coli, P. syringae pv phaseoli, A. tumefaciens and E. carotovora subsp carotovora.  Acts synergistically with PINB against bacteria.  Contributes to grain texture and hardness.
What are the official names of this protein?
Puroindoline-A.
What are the subcellular locations of this protein?
Membrane. Secreted, extracellular space.