PharMolix/UniProtQA huggingface dataset:
Protein: MPTA_THEKO
Sequence: MFVETQEEVPEIREPLRRVGITNLRTVAKINWKGREYTFLPLIEVTIDVPAEKKGIHMSRLVESITEAMSEAVEEEVAKVHSSLEELGKSVIERLEGKHPHKRAEVWIKTHLIIPRTTPASKKTSYEPYDVEVGVIKNEDGSFEKVLRVRVIGNTACPHAMANNNGKTHIQRAIGELEIRAPFEEEIPLEEMIDVVESSFSHPTYTLLKTVDENAVVQGMFANPKFVEDVAREIFAKAKERFRGRIHVRVISNESIHKHDVIAETWS
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA, GTP cyclohydrolase IV.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: RS11_MICAN
Sequence: MARPTKKTGPKKQKKNIPTGVAHIQSTFNNTIVTIADTKGDVISWASAGSSGFKGAKKGTPFAAQTAADNAARRAIEQGMRQLEVMVSGPGAGRETAIRALQGAGLEITLIRDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SPOT_ECO57
Sequence: MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEPYITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSKLDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIARETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILSEIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRVLGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMGVAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPGARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLNEIPQENIQRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPIKGADGVLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQEFITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLANIMRKIRVMPDVIKVTRNRN
What is the function of this protein?
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.  This enzyme catalyzes the degradation of ppGpp into GDP.  It may also be capable of catalyzing the synthesis of ppGpp (By similarity).
What are the official names of this protein?
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase, Penta-phosphate guanosine-3'-pyrophosphohydrolase, (ppGpp)ase.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
Protein: SYY2_STRT2
Sequence: MKLFEDLQWRGLVKQYSSDSLIEKLNNGKLTFYIGTDPTADSLHLGHYSSFLIAKRLAKYGHQPIILIGGATALVGDPRGTSERDLAEQEKIFDNFEKLKNQIQKIFPYEIVNNYDWTKNIMAIDFLREFGKHITAGYMSNKELVKRQFATGISFTEFSYMLLQGMDFYHLFTTKGVTLQIAGSDQWGNMTTGIDLVRKKTGEEVFAMTMPLITDEEGKKFGKSEGNAIWISENKNTPEELHNFLLNVSDDIVISLLKKLTFLSRKDIEEIESRHKNGTGYAQGILADTVTFDIHGVSINKK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase 2, Tyrosyl-tRNA synthetase 2, TyrRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNB_ANOGA
Sequence: MASGRSSIYQDLSEEHPRKLIPELCKQFYNLGWVTGTGGGISIKLDDEIYIAPSGVQKERIQPDDLFIQNIEGDDLQTPPDYKKLTKSQCTPLFMLAYKERSAGAVIHTHSPAAVMTTLLWPGKEFRCTHLEMIKGIYDYELNRNLMYDEELVVPIIENTLFEKDLEESMANALRDYPGTSAILVRRHGVYVWGHNWQKAKTMAECYDYLFSLAVEMHKVGLDANAVPKRY
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Probable methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STP2_MACFA
Sequence: MDTKTHSLPITHTQLHSNSRPQSRSQCTCTHHCQTFSQSCRQSQRGSRSRSSSQSPATHQNPTGAHSSSGCQSQSPNASPPPKRHKKTMNSHHSPTRPTILHSSCPKNRKNLEGKLNKKKMAKRIQQVYKTKKRSSGRKSN
What is the function of this protein?
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals.  In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
What are the official names of this protein?
Nuclear transition protein 2, TP-2, TP2.
What is the protein family that this protein belongs to?
Belongs to the nuclear transition protein 2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome. Note=Loaded onto the nucleosomes of condensing spermatids (By similarity). Nuclear import is mediated by IPO4. Nucleolar localization requires the protein to be phosphorylated (By similarity).
Protein: MGE2_ARATH
Sequence: MLVLRILSRVTRNAGIRSSLSAVTLPARNQTPVFSSRFHSLAHDFSHKLVPAQMSMMDSFALQRFNFSSSTSPESDEKKTHTEASKTSEEKPTAEANQPGLDSESKDSVTDSAKRKRKGAKGAASSSSESDSESDDDELSADDLVKLVAEKEELLSEKEEEIKQLKDKVLRTYAEMENVMDRTRRDAENTKKYAVQNFAKSLLDVADNLGRASSVVKESFSKLDTSEDSAGAAPLLKTLLEGVEMTEKQLAEVFKKFGMEKYDPINEPFDPNRHNAVFQVPDASKPEGTVAHVLKSGYTLYDRVIRPAEVGVTQGGENQEEKKESDA
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity).  Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).  Binds ATP (By similarity).  Interacts with copper ions Cu(2+) (PubMed:20018591).  Confers thermotolerance to long-term exposure at moderately high temperature (TMHT at 35 degrees Celsius) (PubMed:22128139).
What are the official names of this protein?
GrpE protein homolog 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GCH1_CLONN
Sequence: MIDYEKIKKAVIMIIEAIGEDPNREGLKETPDRIARMYEEIFSGIRETPEKHLSKVFKVNNDDVVVEKDIQFYSMCEHHFLPFFGKVHIAYIPNGKVVGLSKLARTTEVFSKRPQLQERLTSQIADSLMEYLKCKGAMVIIEAEHLCMSMRGVKKWGSKTTTIVTRGEFQKDNSLKQDVLNILRL
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CHO2_PHANO
Sequence: MADINHDGPKADGSQMRERPSAKPLHLYNSEDAKKKVLELNQEEEDNKHEEKRKTFGRTPDGTVFIVPQTHDMVSQLLSPSQPKNLSDLAILAVLASLIFTLYICPTSARKPVFAAIFLFWRAAYNAGIGWLLEGQSKHNRLVLWAKNSHIFENPETGNNPHPTIYKLIKREMETKIPKDYKFEEAPLEYNTWLVFRRVVDLILMCDFVSYCLFAIACFNRPPESWLLFGLRWTTGIVLFIFNVFVKLDAHRVVKDFAWYCYHVLFISIVAHAAQFAFLTLVEEPHIQKIYNPPPPRRMRQNSEKFNPEDRPATAHSDATYTDTGVIYDSVRQPAPMHHIVGLQNTDFHRSIDVTVVLLCFYMFCLATVTPNTIAVRLFLFVHAFVWRLWYALGLGYILDRQSKKKNWTRHFIKHGDTKEEAWRQWKSLYHLSMTMCHASFGAAVWKMYELPSDWFLGLTLLRHVLGAGLLLLQLWTSTSIYDSLGEFGWFCGDFFFDPPSSNLTYSGIYRFLNNPERVLGLAGVWGLALITWNPPIFYLAATAHILNLAFLQFVERPHMQRLYGRKLRAESGVSKTLRQAMPSPVRNWQSAADDYVNSTVEFIEDLLEHARPKLAAGYETIVKDTTALFKTYPARISITRVPQDLAGLDPKQYKLEIEGTPSAPTVEIQKHGGREGELARTPATRTSEFKTLTFEYGAPIRVRWQAPVNHHKKDWIGLYMVTDNQSREVTRISSNGRWVATNKGVYDSTRAEDGILVSDRLVSVNSDEDEGGDCYTGEVEFRGDKLWWTTGVFEFRYHHGGKHHVMALSQAFEIRIARFDEDDVEVDANGTVHRAVEQALLPVIQNCFDRDPEIAPSTPEESFGSLVERDGKFAKRVVFAVHQMFGIEFAPEVVQADGNARNLAWRICNAKKILAPYSMSASRGRNTPTSR
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AJM1_HUMAN
Sequence: MTRTDPPDLLVSTVYQDIKVATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSGPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGTAPPGTPALPAPAPRSHGPTVRKFAKVALAAGSPARPPPARSREPDMETLILTPPPGTAGLDQDGEAGRRAREVAFIHIQRELRLRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM
What is the function of this protein?
May be involved in the control of adherens junction integrity.
What are the official names of this protein?
Apical junction component 1 homolog.
What are the subcellular locations of this protein?
Apical cell membrane. Cell projection, cilium. Cell junction, adherens junction.
Protein: HIS7_PSEPG
Sequence: MVERKASVERNTLETQVKCSINLDGSGKARFDIGVPFLEHMLDQIARHGLIDLDIECKGDTHIDDHHTVEDVGITLGMAFAQAIGDKKGIFRYGHAYVALDEALSRVVIDFSGRPGLQMHVPYTRASVGGFDVDLFQEFFQGFVNHALVTLHIDNLRGHNTHHQIETVFKAFGRALRMAITLDERMAGQMPSTKGCL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5184_VIBVU
Sequence: MGRSFEVRKASMAKTAGAKIKVYSKYGKEIYVCAKNGGIDPDMNLSLRHLITKAKKDQVPSHVIEKALDKASGGGGEDYQPARYEGFGPGGISVIVDCLTDNGNRTFQDVRQCFVKTGAKIGTPGVVAHMFDHQAVFQFKGDDEESFLEALMMADCDVTDIELEDGVITIYAPNTEFFKVKTALNTEFPDLVIDVEEITFVPQNYSPVPEEDAEKFQKFLDMLDDCDDVQQVYHNAEM
What are the official names of this protein?
Probable transcriptional regulatory protein VV2_1184.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_PSEA7
Sequence: MSIETFTPTPLLFTPGAANKVKTLIDEEGNPRLKLRVFVTGGGCSGFQYGFTFDEDIADDDTVIERDGVGLVVDPMSFQYLAGSEVDYQEGLEGSRFVIKNPNAATTCGCGQSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RIMM_BORA1
Sequence: MSERTLPDDLVELGRVASAYGVKGWIKVQPHSAQADVLRAAKQWWLAATPKSAPRVYAVQQCRVHGATAVAQLEGIADRDQAEALRGATVWVSRALFPAAAEDEYYWIDLVGCAFYSSVSGSDVRVGVVEEVFDNPAHAILRVVCQDAEGKALLDAKGRAREMLVPFVSAHIQAVDIAARRIDSDWPLED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLP1_RAT
Sequence: MSLRQLLLRLSGYLGASGPPNRHWWYFRSLDTISSVGSWRGRSSRSPAHWNQVVSEAEKIVGYPASFMSLRCLLSDELSNVAMQVRKLVGTQHPLLTTARGFVHDSRHNLQLRGLVVLLISKAAGPSTRNSSSQNYDMVSGIYSCQRNLAEITELIHTALLVHRGIVNLSELQSSDGPLKDMKFGNKIAVLSGDFLLANACNGLALLQNTKVVELLASALMDLVQGIYQENSASTQGNPIPDDIRISTWKEQTFLSHCALLAKSCKAAMELAKHDAAVQDMAFQYGKHMAMSHKINSDLQPFIKDKASDSKTFNLNSAPVVLHQEFLGRDLWIKQIGEAQEKGRLNYTKLRETIKAGKGVTSAIDLCRYHGNKALEALESFPPSEARSALENIVFAVTRFS
What is the function of this protein?
Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone.  Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9) and ubiquinone-10 (Q10) respectively.  The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry (By similarity).  May play a role during cerebellar development (By similarity).  May regulate mitochondrial respiratory chain function (By similarity).
What are the official names of this protein?
All trans-polyprenyl-diphosphate synthase PDSS2, All-trans-decaprenyl-diphosphate synthase subunit 2, Decaprenyl-diphosphate synthase subunit 2, Solanesyl-diphosphate synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CARLK_ARATH
Sequence: MFLKLFLLLSLVSFSHSDSSSTVSCPNGTDFHQLTTVFRYVSGFNSSWFSSNCSAVITHVVLPSRKLNGTVSWNPIRNLTRLRVLDLSNNSLDGSLPTWLWSMPGLVSVNLSRNRFGGSIRVIPVNGSVLSAVKELNLSFNRFKHAVNFTGFTNLTTLDLSHNSLGVLPLGLGSLSGLRHLDISRCKINGSVKPISGLKSLDYLDLSENSMNGSFPVDFPNLNHLQFLNLSANRFSGSVGFDKYRKFGKSAFLHGGDFVFNDSKIPYHHRIHRLPHRHPPPVRQRNVKTHRTNHTPLVIGLSSSLGALIIVIFAAAIILIRRRMKSARTKSRWAISNPTPLDFKMEKSGPFEFGTESGSSWVADIKEPTAAPVVMASKPLMNLTFKDLIVATSHFGTESVISDGTCGPLYRAVLPGDLHVAIKVLERIRDVDQNDAVTAFEALTRLKHPNLLTLSGYCIAGKEKLILYEFMANGDLHRWLHELPAGETNVEDWSADTWESHVGDSSPEKTNWLIRHRIAIGVARGLAYLHHVGTTHGHLVATNILLTETLEPRISDFGINNIARTGDDTNKNNVEFDVYSFGVILFELLTGKQGSDENVKSVRRLVKERRGEEALDSRLRLAAGESVNEMVESLRIGYFCTAETPVKRPTMQQVLGLLKDIRTVSR
What is the function of this protein?
Can phosphorylate the myelin basic protein in vitro (PubMed:14720124).  Required for endosperm development in embryos (PubMed:15634699).  Maybe involved in auxin and osmotic stress responses (PubMed:21431781).
What are the official names of this protein?
Calmodulin-binding receptor kinase CaMRLK, Calmodulin-binding receptor-like kinase, AtCaMRLK, Protein MATERNAL EFFECT EMBRYO ARREST 62.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CYB_FUKDA
Sequence: MTNIRKSHPLMKIINHSFIDLPTPSNISSWWNFGSLLGICLILQIVTGLFLAMHYTADTTTAFSSVAHICRDVNYGWLIRYVHANGASMFFICLYVHVGRGIYYGSYMFTETWNMGVILLFSVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIITALTVVHLLFLHETGSNNPSGIDSDSDKIPFHPYYTIKDFMGFLFVFIILLTLVLFSPDLLGDPDNLYPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSIVILIIMPLLHTSKQRSMMFRPMSQCLFWILVANLLTLTWIGSQPVEHPYILIGQLSSMLYFTIILILMPLVSMMENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYM_CUPNH
Sequence: MTARRILVTSALPYANGQIHIGHLVEYIQTDIWVRFQRMMGNEVYYVGADDTHGTPVMLRAEKEGITPKALIDRVWTEHKRDFDSFLVSFDNYYSTDAEENRELCEKIYLALKAEDLIAEREVEQFFDPVKNMFLPDRFIKGECPKCGAKDQYGDSCEVCGTTYVPTDLKNPYSVVSGATPVRKSSAHYFFKLSDPRCETFLREWVADLAQPEAANKMQEWLGAEGEASTLSDWDISRDAPYFGFEIPGAPGKYFYVWLDAPIGYYASFQNLAAKKGIDFDAWVGPHSTAEQYHFIGKDILYFHTLFWPAMLRFSGYRTPTNVFAHGFLTVDGAKMSKSRGTFITAQSYVDTGMNPEWLRYYFAAKLNASMEDLDLNLDDFIARVNSDLIGKYVNIASRAAGFLVKRFEGKVDEAALAHPLLEQLRQAAPQVAHLYEAREYSKALRLVMELTDAVNAFVDTEKPWELAKDENKRAALHAACSVSLEAFRLLTVYLKPVVPNVAAGVERFLNVEPLDWRAIDKQLSAASPVQAYQHLMTRVDAKQVDALLAANRESLQATAAPAAAGAAIEPIADTITIDDFAKVDLRVAKIVECQKVEGSNKLLQLTLDLGEGRTRNVFSGIQSAYTPEQLVGKLTVVVANLAPRKMKFGVSEGMVLAASAADEKATPGLYILEPHEGAVPGMRIG
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELMO3_MOUSE
Sequence: MAPPRNVVKIAVQMSDAIPQLIQLDQAKPLATVLKEVCDAWSLTHPEHYALQFADGHRKYITENNRLEIKNGSILCLSTAPDLKAQQLLGRLQNTSREGCCEVLRNLVLLASDMTFAQEVISRDGLQKLSTIIENGDDLGEMLALGLRAFLELMEHGVVSWETLSISFVRKVISYVNMNLMDASVQPLALRLLESVTLSSPALGQLVKSEVPLDRLLVHLQVMNHQLQTKAMALLTALLQGASPTERKEMLDHLWKKNLRQFIYKNIIHSATPMGDEMAHHLYVLQALTLGLLEPRMRTPLDPYSQEQRDQLQALRQAAFEPEGESLGTGLSADRRRSLCVREFRKLGFSNSNPAQDLERVPPGLLALDNMLYFSRHAPSAYSRFVLENSSREDKHECPFARSSIQLTALLCELLRVGEPCSETAQDFSPMFFSQDHSFHELFCVAIQLLNKTWKEMRATQEDFDKVMQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKLKPELMGLIRQQRLLRLCEGMLFRKISSRRRQDKLWFCCLSPNHKVLQYGDVEEGAKPPTLESLPEQLPVADIRALLMGKDCPHVREKGSGKQNKDLYELAFSISYDHGEEEAYLNFIAPSKRDFYLWTDGLSALLGSTMGSELTRLDLEQLLTMETKLRLLELENVPIPEQPPPVPPPPTNFNFCYDYSITEP
What is the function of this protein?
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility.  Acts in association with DOCK1 and CRK.  Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases.  May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).
What are the official names of this protein?
Engulfment and cell motility protein 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFD_ARCFU
Sequence: MLVLSGGTGTPKLLQGLKEVADFWVVVNTAEDVWVSGNKICPDIDSVIYAIAEVIDDEKWWGIKGDTFHTHERLKELGFDEGMRIGDLDRATHILRSEMLRAGKSLCEATKAVAEAYGVKQEIFPMCEEEVSTTVVTDEGEMHFQEFWVLRRGEPEVKDVYFRGIEKARIPDEVKERLRKEKEVLIGPSNPITSILPILSVEDFRERLRDKKVIAISPIVGEKAVSGPAGKLMRAKGYEVSARGVADVYADFLDLLVVDEADKGVMERSVATNTIMKTKEDAVRLAEFVVKLFDGL
What is the function of this protein?
Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
What are the official names of this protein?
2-phospho-L-lactate transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: CLPP_ACIAC
Sequence: MSALETQALGMIPMVIEQSGRGERSYDIYSRLLKERIVFLIGEVNDQTANLVVAQLLFLESENPDKDISFYINSPGGSVTAGMAIYDTMQFIKPDVSTMCLGFAASMGAFLLAAGAKGKRFSLPNSKIMIHQVLGGARGQATDIEIHARDILRTKDQMNRILAERTGQPLEKVKADTERDYFLTADEAKEYGLVDQVVTQRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CML12_ORYSJ
Sequence: MQSQRERPREDRVHEETRGADHAHPSVPHAAAAASATATETATRTMSLHAGGVVVVDGKEKGKKEEGEGKRKGKAPATAEAVRGRARLRGEQLRQLHEIFLRFDLDGDGSLTKLELAALLRSLGLRPAAGDEIHALIAAIDADGNGTVEFDELASSLADLILGPCRPSVAVDQAELAEAFRAFDRDGNGFISAAELARSMARMGHPICYAELTDMMREADTDGDGLISFEEFTAIMAKSALDFLGLAAL
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML12, Calmodulin-like protein 12.
Protein: RL17_SOLM1
Sequence: MRHNKSGRKLGRTAAHRKAMLRNMARSLLIHERIRTTEHKAKELRGVVEQLVTLAQTDSVHARRMAYKVLENHQLVARLFNEIGPRFTGQPGGYTRVVKMSLPRAGDCAAMAIIELTKLAGAAPAGQEQAPKDASSEA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SYGA_STRM5
Sequence: MSATPTVPITFQGLIQTLNQFWAQQGCVLIQPLDLEVGAGTFHPATFLRAIGPESWNAAYVQPSRRPTDGRYGENPNRLQRYYQYQVAMKPAPDNIQQLYLDSLKALGIDPLVHDLRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGLECRPVLGEITYGLERLCMYLQNCDNVYDLVWTYGPDGQPVTYGDVYHQNEVEQSTYNFEYADVEEMFHRFDACEREAQKLVEVNLPLPAYEQVMKASHTFNLLDARRAISVTERQRYILRVRALAQAVAKAYYEQREKLGFPGAKKA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK3_KARBO
Sequence: DPPFSPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-3, PK-3, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TAT_SIVTN
Sequence: MNPIDPQVAPWEHPGAAPETPCTNCYCKKCCFHCPVCFTKKALGISYGRKRRGRKSAVHSTNNQDPVRQQSLPKRSRIQNSQEESQEEVEAETTSGGRPRQQDSSVSSGRTSGTSSSGYTRPFKTSSGSSGSACKH
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: CYPK_STRCO
Sequence: MSRPGEHRVVHTLRTQAPARRLYELVARVEDWPAVFEPTVHVQVLERGPGTERFRIWARVGGRVKTWTSRRTLDPDTLRVTFRQELTQPPIASMGGSWEFRGDGDGTEVVLTHDFAAVDEAALPGLREALDANSGKELAALVALAERRQPPEELVFTFEDTLRVPSGDDAYAFIERSDLWQERLPHVRKVTLTEEAAGTGPAETRDMTVQDMTMETVTTDGGTHTTRSIRLCVPARSIVYKQLVPPALLSGHCGAWTFGEDTVTARHTVAIDPARVEEVLGKGATVADARTHLREVLGANSRATLRHAAAAAGPAS
What is the function of this protein?
Is needed for correct cyclization of the oligoketide leading to isochromanequinone formation.
What are the official names of this protein?
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase, ACTVII, actI ORF4.
Protein: Y046_UREPA
Sequence: MKFIKRKTKLLTITIGAVAVSSILLGGIFYGTSQKSPSSFGIASIDQKENFINKDNLDYQKARPSIKDNNLKEIPKPKPQPKPEPQPTPFPDPIPTPPKKEELKKPEIKPEEPKKPEIKPEPIPKPKPQPIPQPTPPVETKPKEELLPPSPPPPKEEPKPEPDPQPQPQQIPNQSTVRKIELNGVLVDAEVEVPPPRQTFKYDQDNGLSNLNPYTNISVGKIKKVFVTDELRHKSADLVRGNLKRGDYQSLVKDLLDPNIKPEEIDSYIAMVDKSGYHAKLWSKFKKLFDTDNVVNFLNEQGKKEYPNMKTKFVSDAHKYAWLYAHLDFSKFTKLSANSEKYLQEGLTPDPDNSYVNENGELDSYAYSPAKEYNTVTSRLANDNANRRVFGYNEWYNRSPNGLANGDYPGWNKSDATAEFKQYGIKDGDGIKVYKLERQKPQEGKLNTGYIVDIDADNPDGYQKTKELIQKLNNQNKKITGYRIRNMGKSDSGQKFSDILKALPNELPLLELFFSAGSHNTSALSALETKHIKELGLYTLGNSLLDEWSINPNALRKVEWINSNDYNVSSEYKQGSDIATRITFDTLSFDKNDFNDNANDLRTKLKRINDGLRMVYWTRNNEPFFQGGFGPGLDPDHKEVGNSYPQGLDFSRVPQIRSLRGLIFKDEQKASNNRERKLRRVNFFNDKENYEMSINDLNEAGFSEHIVTNEPMPPKSKITFSNGNATKRIYIKGNGSLTASGIQNLATLFNLAESLDSKSVVVDSNNSELKSQLEGLGYKVSDASDANYIDI
What are the official names of this protein?
Uncharacterized protein UU046.
What is the protein family that this protein belongs to?
To U.parvum UU044.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.