PharMolix/UniProtQA huggingface dataset:
Protein: MDH_SHEHH
Sequence: MKVAVLGAAGGIGQALALLLKTQLPAGSKLSLYDIAPVIPGVAVDLSHIPTAVEVKGFAGEDPTAALEGADVVLISAGVARKPGMDRSDLFNINAGIVRNLVEKCAATCPKALIGIITNPVNTTVAIAAEVLKKAGVYDKNRLFGVTTLDVIRSETFVAEAKDLNVADVKVPVIGGHSGVTILPLLSQVEGVSFTDAEIAALTTRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLVRGLQGEANVVECAYVDGGSEHTEFFAQPVVLGKNGIEQVLAYGEVSAFEANARDAMLDTLKADIQLGIEFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: MUK1_YEAST
Sequence: MARQLFTPPITNPRFDPNQSIRESYKNTTGGMQFQQNLHEDQNDNERSSCDGDENSTTGERLENNKSPILTKQEIDEALNTVTNLPPELSKLIDIFIDDLKQPKYVRPLSVLQLSSLFQSFYIKFDKASFQHVSSANNNGYYFSGGGSSSFLAAKETLSSGLSGIFGRSRSSSGNSLMRPRRSSSLFSNESISNSTNATQMLSPEEIKKQLKINELNNMKIEKYMELCERDVFKKILIVGTSVSSPNKMKTFKPHQLQTFKVGNLFRNSVEFTEYNKLLNEKILCLSKLSTMNKINLIKFLSLNNGIDPEPKFEEIKDILYEFTYHSISPCEKIKALLKLHEIMTYSQEMSNDDYLSLLIYYIITIVPRDIFLNAEFIRLFRYKKKLVETESFALTNLEAALVFVEGLTKNDFSNELQDKLTVNESKILENSISSRVSLPSKTAIMHKNNGNNGSNLGDIVTPTIQRPDVTRSNSYDGFRTVFDSSLKNIIGKIRSYTPPHPNNTSNNNLHSSNNLNIPRSSSQLSMELSNRDTTEMSRDGSRSTSSSSRSSASLEHGNREFTGDLTVTASINGADKKEFQKSWKKYKGYKFEDLTICELRDLFEIYQKMMQ
What is the function of this protein?
Putative GTPase-activating protein.
What are the official names of this protein?
Protein MUK1.
Protein: SSRP_PARXL
Sequence: MSIIDNRKAFYDYSVEERYEAGLVLEGWEVKALRAGRGQIKEGYVVIKNNELFLIGTHISPLPEASTHINPDPVRTRKLLLHSEEISKLIGKVEQRGYTLVPLNFHYKGGRVKCEIGLAKGKKQHDKRETEKKRDWEREKARLMRSPG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RNH_PELPD
Sequence: MSARPDQSRTAAPSATTSPVEIYCDGACSGNPGPGGYGAILRYNGHEKEIRGSEAHTTNNRMELTAAMEALRLLTRPCRITIVTDSQYLVKGMTEWIQGWQRRGWQNSKKEPVLNRDLWEELLKLSAHHDVSWQWIRGHAGHAENERCDSLARQAITEMRGAP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_BACCR
Sequence: MNLETIIGLEVHVELKTNSKIFSASPTEFGAEPNTQTSVIDLGYPGVLPTLNKEAVNFAMKAAMALNCEIATETKFDRKNYFYPDNPKAYQISQFDKPIGENGWIEIEVDGKKKRIGITRLHLEEDAGKSTHTADGSLVDYNRQGMPLIEIVSEPDMRTPEEAYAYLEKLKSIIQYTGVSDCKMEEGSLRCDANISLRPVGQEKFGTKAELKNLNSFTYVQKGLEHEQVRQEKELLSGGIIQQETRRYDEATKKTILMRVKEGSDDYRYFPEPDLVELYIDDEWKEAVRASIPELPDARKARYVAELGLPAYDAHVLTLTKEMSDFFEATVADGADAKLTSNWLMGEVLAYLNKQQKELKDVALTPAGLSKMVQLIEKGTISSKIAKKVFNELIEKGGDPEEIVKAKGLVQISDEGTLRKVVTEILDNNEQSIEDFKNGKDRAIGFLVGQIMKATKGQANPPLVNKILLEEINKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: URE2_JANSC
Sequence: MIPGEVMPADGTIELNAGAQAVTLEVSNTGDRPIQVGSHYHFGEANGALDFDRDAARGMRLDIAAGTAVRFEPGQTREVRLVPYGGARRVFGFNQTVMGDL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_VIBPA
Sequence: MKKSLSLVLASGSPRRKELLAQLGYDFDIVLPDIEEAKQADEQAQDYVLRLSLEKAQAGLALAKPDSVVLGSDTVVVCDDRVLEKPKSFEDSKRMLTDLSGRRHQVMTAVSVVSSEQQHSVVVTTDVWFKPLTHEEIEQYWQSGEPCDKAGSYGIQGLGGRFVTRIEGSYHAVVGLPLFETDQLIQEFL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_STRP6
Sequence: MNFETIIGLEVHAELNTNSKIFSPSSAHFGEDPNANTNVIDWSFPGVLPVMNKGVIDASIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPVGYNGWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNSFSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPDLPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKVLSDFFETAVSLGGDAKQVSNWLQGEIAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVFVHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFTGFLMKATKGQANPQVAQQLLAQELQKLRD
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: MNTH_ECOL6
Sequence: MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALNIWLLVGTALGL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFA_ECO8A
Sequence: MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDTTRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCB_SHELP
Sequence: MNYFELFSLSPSFELDTAVLSERYRELQRAVHPDKFANASEQDKRLAVQHTAQVNDGYNTLKHPISRAEHMLSLKGIDLSHESTTVKDTMFLMQQMEWREALEEISDCDDPDEAIEHLHQSFGEYRGDITAQLAQKIGSEEASVLEQAADLVRKLKFMDKLQAELERAEDALF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: RL4_METB6
Sequence: MKAQVKTIEGGVAKDIELPAMFSEEYRPDLIRKAVLALQSTRRQPHGSYPYAGICSSAVGWGSGRGASHVPRLKNGSRAAKVPQAKGGREAHPPVTAKVLIKEINAKEKQKAFRSAVAASIRADLISSRGHRFEGTVPLIFEDKFENLAKTQEVISALTNIGVYSDIERSKESRKVRAGRGKLRGRRYKQRKSLLIVTSGPEFRAARNLAGVDVVTVDQLNVEHLAPGMQAGRLTVWTESAVIRLEGR
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RL11_VIBVU
Sequence: MAKKVEAYIKLQVAAGMANPSPPVGPALGQRGVNIMEFCKAFNAKTESMEKGLPVPVVITVYSDRSFTFVTKTSPAAVLLKKAAGIKSGSGRPNTEKVGTVTDAQIQEIAEAKAADMTGADIEAMKRSIAGTARSMGLVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: F1711_PONAB
Sequence: MSRSAALLLCLLGCHVWKAVTKTLREPGAGAQEVTLKVHISDASTHQPVADALIEIFTNQASIASGTSGTDGVAFIKFQYKLGSQLIVTASKHAYVPNSAPWKPIRLPVFSSLSLGLLPERSATLMVYEDVVQIVSGFQGARPQPRVHFQRRALRLPENTSYSDLTAFLTAASSPSEVDSFPYLRGLDGNGTGNSTRHDLTPVTAVSVHLLSSNGTPVLVDGPIYVTVPLATQSSLRHNAYVTAWRFDQKLGTWLKSGLGLVHQEGSQLTWTYIAPQLGYWVAAMSPPIPGPVVTQDITTYHTVFLLAILGGMAFILLVLLCLLLYYCRRKCMKPRQHHRKLQLPAGLESSKRDQSTSMSHINLLFSRRASEFPGPLSVTSHGRPEAPGTKELMSGVHLEMMSPGGEGDLHTPMLKLSYSTSQEFSSREELLSCKEEDKSQISFDNLTPSGTLRKDYHKSVEVFPLKARKSMEREGYESSGNDDYRGSYNTVLSQPLFEKQDREGPASTGSKLTIQEHLYPAPSSPEKEQLLDRRPTECMMSRSVDHLERPTSFPQPGQLICCSSVDQVNDSVYRKVLPALVIPAHYMKLPGDHSYVSQPLVVPADQQLEIERLQAELSNPHAGIFPHPSSQIQPQPLSSQAISQQHLQDAGTREWSPQNASMSESLSIPASLNDAALAQMNSEVQLLTEKALMELGGGKPLPHPRAWFVSLDGRSNAHVRHSYIDLQRAGRNGSNDASLDSGVDMNEPKSARKGRGDALSLQQNYPPVQEHQQKEPRAPDSTAYTQLVYLDDVEQSGSECGTTVCTPEDSALRCLLEGSSRRSGGQLPSLQEETTRRTADAPSEPAVSPHQRRSAHEEEEDDDDDDQGEDKKSPWQKREERPLMAFNIK
What is the function of this protein?
Involved in the regulation of the cytoskeletal dynamics, plays a role in actin stress fiber formation.
What are the official names of this protein?
Protein FAM171A1.
What is the protein family that this protein belongs to?
Belongs to the FAM171 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: OTC_HYPNA
Sequence: MTIRHFLDIWPLESAELRAILDQAHAMKKARAGWPKGKIDAGAPLDGHTLAMIFEKSSTRTRFSFDMAMRQLGGSSITATSNDMQLGRGETVEDTAKVLSRFVDAVMIRANDHADVEAFADAASVPVINGLTDRSHPCQIMADLMTLEEHGLTLRGARLAWVGDGNNVCASFIHAAPKFGFSLAVGTPKRFAPDEDDLEIAAELQGRIDLYETAEEAVAGADVVIADTFVSMGDVDAERRLEILDPYAVTEELMELAAGGAKFLHCLPAHRGEEVDAEVIDGPASLVFDEAENRLHAQKAILRWCLGK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_SHEHH
Sequence: MKIQLVAVGTRMPDWVETGFKEYQRRFPRDMALELVEIPAGKRGKNADIARILQKEGELMLAAIPKGNHIVSLDLPGKNLTTPQLAEQMNKWLLDGRDVSLLIGGPEGLSPECKKAAAQSWCLSALTLPHPLVRVIVAESLYRGWSINNNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBT_CHLPM
Sequence: MKEKFLALIAAVSPADHSLSGAAQAHLDDLTKPQGSLGRLEEIALRFVQATASLSPVINRKKICCFAGDHGVAREGVSAFPSEVTPQMVYTMLSGGAAINVFARHVGADLAVVDMGVNHDFPDHPVLVKRKVAKGTGNIAAGPAMSENEAIGAILAGAALAAEAHDEGYHLLGTGEMGIANTTPAAALYSVLLGVPVDGITGRGTGIDDERLQHKKEVIKRAVGVNAGLCTTPLGTLAALGGYEIAGIAGFILGAAACRVPVVVDGFISSAGAVVAMKLCPVVADYLFFSHLSNEQGHRAVMQALGARPILDLDLRLGEGTGAALAMQMIEASVKMYNEMATFSSASVSEKDGE
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: SSRP_BIFLS
Sequence: MPKETGEKLIVQNKKARHDYAIEDKYEAGLALTGTEVKSLREGRASLSEAFISIDRRGEMWLEGANIPEYLNGTWNNHAPKRKRKLLLHRLQITKLARGIEAKGYTIVPLSLYFKDGRVKAEIALARGKKEFDKRQALREEQDKREALRAMRYANMRH
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL11_OLEA2
Sequence: MAKKEIAKIKLQIQAGAANPSPPVGPALGQHGLNIMEFCKAFNARTQDQKGMVIPVVITAYADRSFTFITKTPPASVLLAKAAKVAKGSGEPNKTKVGSVTMEQVEEIAKLKMPDLSAKDLPGAVKTIAGTARSMGIDVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: METE_SHIBS
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHNVKPVLLGPVTWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELEKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDGVAELHKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: HVM05_MOUSE
Sequence: MGWSCIILFLVATATGVHSQVQLQQPGAELVRPGSSVKLSCKASGYTFTSYWMDWVKQRPGQGLEWIGNIYPSDSETHYNQKFKDKATLTVDKSSSTAYMQLSSLTSEDSAVYYCAR
What are the official names of this protein?
Ig heavy chain V region 3.
Protein: ASSY_SULAC
Sequence: MKIVLAYSGGLDTTVAIRWLRETFNADVTTVTVDVGQKDDFYQIEKRAYIAGAIKHYTIDAKKDFAERYISYAIKMNGLYEDIYPLSTALARPLIVEKVVEIAKKIGAEAIAHGSTSKGNDQVRFDLAVKALYPEAKIIAPARIWNMTRDKEIEYAKSKGIPIKTESSKYSIDENLWGRSIEGDIISDPSKEVPEDAFEWTKKTKDDKLKISLTFDKGLPVEVNGEKMDLLKVIQVLNELVGSRGFGRVEHLENRVVGFKSREVYEVPAALVLINSHKDLEKSTYTPLEFRFKRSLDGQWSDLVYQGLWFEPLRETIQIAGDNLNKWISGEVFIEVENGNMKILGRKGKFSPFSEEIASYNKGWYPSDEMARGFIEIFGMHSLVARKSRGI
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_VIBVU
Sequence: MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKARFLGKGVLKAIEAVNGAIADALVGKDAKDQAAIDAIMIELDGTENKSKFGANAILAVSLANAKAAAASKGMPLYEHIAELNGTAGQFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEAVRMGAEVFHNLAKVLKSKGYNTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYVLGKDVTLAMDCAASEFFDKEAGIYNMKGEGKTFTSEEFNHYLAGLVEQFPIVSIEDGLDESDWAGFAHQTQLLGDKIQLVGDDLFVTNTKILAEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALAGRAPFNGLKEVKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: HYOU1_CHICK
Sequence: MARAPRWMLGWLLLACCVPHTEPLAVMSVDMGSESMKIAIVKPGVPMEIVLNKESRRKTPVAVALKENERLFGDSALGMSIKTPKVAFRYFQDLLGKQIDNPQVALYQSRFPEHELVKDEKRQTVIFKLSQTLQYSPEEMLGMVLNYSRGLAEEFAEQPIKDAVITVPAYFNQAERRAVLHAARMADLKVLQLINDNTAVALNYGVSGGKTSMPLHSFSFQNIMFYDMGAGSTVCTIVTYQTVKTKDSGTQPQLQIQGIGFDRTLGGLEMELRLRDYLAKLFNDQHPSKDVRKNPRAMAKLLKEANRLKTVLSANADHMAQIEGLLDDIDFKAKVSRQEFEDLCSDLFQRVPGPVQQALSSAEMNLDGIDQVILVGGATRVPKVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFMVRDAAMFPIQVEFTREVEEDDKSKSLKHNKRILFQRMAPYPQRKVITFNRYTDDFEFYVNYGDLSFLNQDDLRIFGSLNLTTVRLKGVGESFKKHSDYESKGIKAHFNMDESGVLSLDRVESVFETLVEDKLEEESTLTKLGNTISSLFGGGGHTPEAGENLTDSVQEEEESLAEAAKEEQGVKQGQKSSAEDAGEEQGEEKQQSPHPDQAEAVPPKEESQKNEEGEKSEARDPKEDKETVNEEELSKSSGAGTAAKAEEEKKIKAPKKQKLVHEITMELDVNDVPDLLEDELKSSMKKLQDLTIRDLEKQEREKSANSLESFIFETQDKLYQEEYLFVSTEEEREEISKKLSEASNWMEEEGYAAATKELKDKLAELKKLCRNLFFRVEERRKWPERLAALESLLNHSNIFLKGARMIPESDQIFTEVELGTLEKAINETTVWKNETLAEQNKLSPAEKPVLLSKDIELKIAGLDREVQYLLDKAKFAKPKPKKEKNATKSDSGKNATGTSESENTIPPTEGKQEEKPEDISPAKEPPTTEKVVTDDEPGSDSSSKKEKKPEAGGESRKNDEL
What is the function of this protein?
Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation.  May play a role as a molecular chaperone and participate in protein folding.
What are the official names of this protein?
Hypoxia up-regulated protein 1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: SULA_EDWTF
Sequence: MRTSPLHPATDSVVFSRPACQSAPTVPQSGFVSELGYGAQQPLLSLLLPPLLRQLGEQSRWQLWITAQHKPSKRWLSACGVPVHKVMQLRRAEAGEAIYAMEQALRSGNYSVVLGWLPPLTAAERLRLNRAAQAGRSIGLLMQPQEGKLAAAAPPQAHAANRGSARYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity).
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: NEUR2_CRIGR
Sequence: MATCPVLQKETLFQTGDYAYRIPALIYLSKQKTLLAFAEKRLTKTDEHADLFVLRRGSYNADTHQVQWQAEEVVTQAYLEGHRSMSPCPLYDKQTRTLFLFFIAVRGQISEHHQLQTGVNVTRLCHITSTDHGKTWSAVQDLTDTTIGSTHQDWATFGVGPGHCLQLRNTAGSLLVPAYAYRKQPPIHAPAPSAFCFLSHDHGSTWELGHFVSQNSLECQVAEVGTGAERVVYLNARSCLGARVQAQSPNSGLDFQDNQVVSKLVEPPKGCHGSVIAFPNPTSKADALDVWLLYTHPTDSRKRTNLGVYLNQKPLDPTTWSAPTLLATGICAYSDLQNMGHGPDGSPQFGCLYESNNYEEIVFLMFTLKQAFPAVFGAQ
What is the function of this protein?
Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins, oligosaccharides and gangliosides.
What are the official names of this protein?
Sialidase-2, Cytosolic sialidase, N-acetyl-alpha-neuraminidase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMK1_YEAST
Sequence: MNCTLTDNTRAINVASNLGAPQQRTIFAKERISIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFTYESELNSMSKLRDYLVEEVKNFKTDLSSSSL
What is the function of this protein?
Required for spore wall assembly.  Required for proper deposition of the two outer layers of the spore wall, the chitosan and dityrosine layers.  Negatively regulates GSC2, an alternate catalytic subunit of the 1,3-beta-glucan synthase (GS).  Participates in a developmentally regulated signal transduction pathway that coordinates cytodifferentiation events with the transcriptional program.
What are the official names of this protein?
Sporulation-specific mitogen-activated protein kinase SMK1, MAP kinase SMK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: DTDH_MUCMU
Sequence: MSTDYLTLNRTGDKMPIRGFGCWKIDTKDCEETVYQAIKTGYRLFDGACDYGNEVEVGRGINKAINEGLVKREDLFIVTKLWNTFHSKKHVRALFDRQLKDTGLEYFDLYLIHFPVPLQYVDPATVYPPGWYVGDAKSLQFEQSPIHECWAELEKIVDAGLARNIGVANFNCQAILDLLTYARIKPAVLQIELHPYLPQERLVKWVKEQGIQITAYSSFGPTSYVDLTESGKTYTSLLEHASVKSVADKHNVSTGQVLLRWALDREFAVIPKSVNAGRMKANLEILDIKLDAEDNKTLDSLKTNQRFNDPMTYGFGLPLFD
What is the function of this protein?
Catalyzes the NADP-dependent oxidation of (+) mating-type specific precursor 4-dihydromethyl-trisporate to methyl-trisporate.
What are the official names of this protein?
4-dihydromethyl-trisporate dehydrogenase, 4-dihydromethyl-TA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: RL23_MYCUA
Sequence: MATIVDPRDIILAPVISEKSYALLDDNVYIFVVHPDSNKTQIKIAIEKIFAVKVASVNTANRQGKRKRTRTGYGKRKSTKRAIVTLAPGSKPIDLFGAPA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.