PharMolix/UniProtQA huggingface dataset:
Protein: AGX1_YEAST
Sequence: MTKSVDTLLIPGPIILSGAVQKALDVPSLGHTSPEFVSIFQRVLKNTRAVFKSAAASKSQPFVLAGSGTLGWDIFASNFILSKAPNKNVLVVSTGTFSDRFADCLRSYGAQVDVVRPLKIGESVPLELITEKLSQNSYGAVTVTHVDTSTAVLSDLKAISQAIKQTSPETFFVVDAVCSIGCEEFEFDEWGVDFALTASQKAIGAPAGLSISLCSSRFMDYALNDSKNGHVHGYFSSLRRWTPIMENYEAGKGAYFATPPVQLINSLDVALKEILEEGLHKRWDLHREMSDWFKDSLVNGLQLTSVSRYPSNMSAHGLTAVYVADPPDVIAFLKSHGVVIAGGIHKDIGPKYIRIGHMGVTACNKNLPYMKNCFDLIKLALQRKK
What is the function of this protein?
Has alanine:glyoxylate aminotransferase activity.
What are the official names of this protein?
Alanine--glyoxylate aminotransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
Protein: INO1_ARATH
Sequence: MFIESFKVESPNVKYTENEIHSVYDYETTEVVHEKTVNGTYQWIVKPKTVKYDFKTDIRVPKLGVMLVGLGGNNGSTLTAGVIANKEGISWATKDKVQQANYFGSLTQASSIRVGSFNGEEIYAPFKSLLPMVNPDDVVFGGWDISDMNLADAMARARVLDIDLQKQLRPYMENIVPLPGIFDPDFIAANQGSRANHVIKGTKKEQVDHIIKDMREFKEKNKVDKVVVLWTANTERYSNVVVGMNDTMENLMESVDRDEAEISPSTLYAIACVLEGIPFINGSPQNTFVPGLIDMAIRNNVLIGGDDFKSGQTKMKSVLVDFLVGAGIKPTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVASNGILFEPGEHPDHVVVIKYVPYVADSKRAMDEYTSEIFMGGKNTIVMHNTCEDSLLAAPIILDLVLLAELSTRIQFKSEGEGKFHSFHPVATILSYLTKAPLVPPGTPVINALSKQRAMLENIMRACVGLAPENNMIMEFK
What is the function of this protein?
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner (PubMed:20215587).  Catalyzes the majority of myo-inositol synthesis required for plant growth and development (PubMed:20215587).  Acts as a repressor of programmed cell death and protects plant cells against cell death under high light intensity or long days (PubMed:20215587).  Controls its own transcription by inhibiting ATXR6 activity (PubMed:23341037).  Reduces the deposition of inhibitory histone marks on its own promoter (PubMed:23341037).
What are the official names of this protein?
Inositol-3-phosphate synthase isozyme 1, AtIPS1, MIP synthase 1, Myo-inositol 1-phosphate synthase 1, AtMIPS 1, MI-1-P synthase 1.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: 5NTC_XENTR
Sequence: MTTSWSDRLQNAADLPANMDGHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFDLTVERLVSIGYPQELLNFVYDPTFPTRGLVFDSTYGNLLKVDAYGNILVCAHGFNFMRGPEIREQYPNKFIQRDDTDRFYILNTLFNLPETYLLACLVDFFTNCDRYTSCEMGFKDGDLFMSFRSMFQDVRDAVDWVHYKGSLKEKTVENLPKYVVKDPKLPLLLSRMNEVGKVFLVTNSDYKYTHKIMTYLFDLPHGPKPGSSHRLWQTYFDLILVDARKPLFFGEGTVLRQVDTNTGKLKIGTYTGPLQHGIVYSGGSSDIVCDLLGAKGKDILYIGDHIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTHVDIHETESPMATRNRCSLDFKDSDFKRHQLTRSISEIKPPNLFPQKPQEITHCHDEDDDEEEEEEEEEEEEEEE
What is the function of this protein?
Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates.  In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine.  Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP.  Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency.  Through these activities regulates the purine nucleoside/nucleotide pools within the cell.
What are the official names of this protein?
Cytosolic purine 5'-nucleotidase, Cytosolic nucleoside phosphotransferase 5'N.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TYRP2_CHICK
Sequence: MGALRWLFWVGLSYLSCCRLPRAEAQFPRVCMTVEAIRSKRCCPALGPDPGNVCGVLQGRGWCQGVQVDTQPWSGPYTLRNVDDRERWPLKFFNQSCWCTGNFAGYNCGDCKFGWTGPDCSVRKPPVVRKNIHSLTVEEREQFLDVLDRAKTTIHPDYVIATQHWMSLLGPSGEEPQIANCSIYNYFVWLHYYSVRDTLLGPGRPFTAIDFSHQGPAFVTWHRYHLLLLERDLQRLMGNESFALPYWDFATGRNTCDVCTDQLFGAPRPDDPGLISLNSRFSRWQIVCNSLDDYNRLVTLCNGSDEGLLQRRPRDSGEQLPTAEDVRRCLSRHEFDSPPFFRNSSFSFRNALEGFNKPEGALNSPMLNLHNLAHSFLNGTRVLPHAAANDPIFVVLHSFTDAIFDEWMKRFHPPDNAWPEELAPIGHNRLYNMVPFFPPVTNDQLFQTAEQLGYTYAIDLPGSLEESQAWAAMVGSTIGGALIALAVLVLLLVLFQHRKQRKGFEPLMNVRFSSKKYMEEA
What is the function of this protein?
Plays a role in melanin biosynthesis.  Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
What are the official names of this protein?
L-dopachrome tautomerase, DCT, DT, L-dopachrome Delta-isomerase, Tyrosinase-related protein 2, TRP-2, TRP2.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Melanosome membrane; Single-pass type I membrane protein. Melanosome. Note=Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.
Protein: ARYLT_MYCBO
Sequence: MSASLLVRTACGGRAVAQRLRTVLWPITQTSVVAGLAWYLTHDVFNHPQAFFAPISAVVCMSATNVLRARRAQQMIVGVALGIVLGAGVHALLGSGPIAMGVVVFIALSVAVLCARGLVAQGLMFINQAAVSAVLVLVFASNGSVVFERLFDALVGGGLAIVFSILLFPPDPVVMLCSARADVLAAVRDILAELVNTVSDPTSAPPDWPMAAADRLHQQLNGLIEVRANAAMVARRAPRRWGVRSTVRDLDQQAVYLALLVSSVLHLARTIAGPGGDKLPTPVHAVLTDLAAGTGLADADPTAANEHAAAARATASTLQSAACGSNEVVRADIVQACVTDLQRVIERPGPSGMSA
What is the function of this protein?
May be involved in the import of arylamide compounds.
What are the official names of this protein?
Putative arylamide transporter.
Protein: PHS_RHIME
Sequence: MRPEKLDAAAIAEHLHKMEGWVLAEDGGSIWKTFRFKTFAEAFTFMTQCAFAAEKLNHHPEWFNVYNKVDVTLSTHDADGLTELDFKLAAKMDQAAEGRMPDHM
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: RL5_RUMCH
Sequence: MTRLKDKYLNEAAPALIEKFKYSSRMQVPKLEKVVLNMGVGEVKDNPKAMDSAVNDMTLITGQKPIVTKAKKSVAAFKLRQGMNIGCKVTLRGDRMYEFVDKLFNVAIPRVRDFRGLSSNSFDGRGNYSMGIKDQLIFPEIEYDKVDKLRGMDIVFVTTAKSDEEAKELLKLLGMPFSQN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MURI_CARHZ
Sequence: MDKASLGIGIFDSGVGGVTVLKELINLLPGENFYYLGDTAHVPYGSKSKEELLILGDAIIRFFLKLGVKMVVFACNTSSAITLPILKERYPVLMEGMLEPLRKNMPAKAKVGVLATEATVKSGLYQKKLMETNKFQEVYMIACPQYVPLIEKGIVSGKEVEEATREYFEPLLKEEVRDVVLGCTHYPFLTETIQKLYPKIQVIDPAAYVAREVYRKLKENKLLGENGGKVQFYVTGDEKSLKNLGSLYLGYNIDRVQKIDLEVIV
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: RL2_CAMLR
Sequence: MAIKTYKPYTPSRRYITGVSSEDITAKASVRSLLVKLPAHAGRNNNGRITSRHKEAGAKKLYRIIDFKRRKFGIEGKVEAIEYDPYRNCRIALISYRDGEKRYILQPKGLGVGDVVCAAESGLDIKPGNAMKLRNIPVGTIVHNIELKPGKGGQMIRSAGAYAQLMGKEEKYVILRLASGEMRQVLAECMASIGEVGNEEWSNVTIGKAGRNRHRGIRPQTRGSAMNPVDHPHGGGEGKKNSGRHPVTPWGKPTKGAKTRRKKASDKLIISRRKGK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TOLB_IDILO
Sequence: MKNILIRSILLFVALTAFVRAGVLEIVITEGIDTARPIAVVPFQWKGEGKAPNELTDVIAADLMRSGKFNPIPVSAMPQRPAADDEIDYSAWAKMGVEAILVGSIEPYSVDRYMVKFEVIDVLRGQITGGNSQMLRNGELVQSNDHVLDSRSSVIDGDQFRSYAHRISDVAYEALTGERGAFMTKIAYVTVNHDDRYPYKLAVADYDGANEKILLRSPEPLMSPAWSPDGNKLAYVSFENKTAEIFMQDIYTTRREKLTSFPGINGNPVFSPDGKKLAMVLSKDGNPELYVFDIKTKDLQRVTRNRTIDTEPNWTPDGESLVFTSERGGRPQLYSVNLSSGQVRRLTFDGEQNLGGTLVPSGEDMILVNRTRGNYHIAKQEFPRGNMQVLTKTSLDESPSVAPNGSMVIYSTTHNNKQVLALVSIDGRFKARLPATDGEIKSPAWSPFM
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSAC_ORYSA
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGPETTRSMALSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: PAF1_SCHPO
Sequence: MENRRQDYILRVRYHNPLPPPPFPPKLINIPNPVKQYALPNFVSTLVQEKKIPIENDIELGMPLDLAGITGFFEGDTSWMHSDLSSVNLDPIDRSLLKVAGGSGSTHLEVPFLRRTEYISSEVARAASNRGNLRLTASTSKALAEQRGRSLREVPKQLEAINESFDVVQQPLEQLKHPTKPDLKPVSAWNLLPNTSMAGIQHLMLRVADDLSERSHSYSSLVNLQEGHNLTKRHEVALFMPSSAEGEEFLSYYLPSEETAEEIQAKVNDASADVHEPFVYNHFRNFDASMHVNSTGLEDLCLTFHTDKDHPEANQVLYTPIYARSTLKRRHVRAPVSLDAVDGIELSLRDLNDEESLQLKRARYDTFGLGNIKDLEEEEEKLRSVEGSLNEELSEEEKPAESREQLESAEQTNGVKPETQAQNMSASESQANSPAPPVEEGNTQPSPVEQLQNEED
What are the official names of this protein?
RNA polymerase II-associated protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the PAF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SDHD_ACISJ
Sequence: MPSVVSPQDHLQDDAPAAQLRRAEPCLWLNPHRQPIPAARQAVAGDHISLDDTEKAAARFARFAPLLEGVFPELQATGGVIESPLLPASSLHAAAGLVAGQGALWIKADHRLPVAGSIKARGGIHEVLELAERLALQHGLLTPQSDADDYRALANPAARAVFARYTVAVGSTGNLGLSIGVAASALGFHAVVHMSADAKEWKKQRLRQRGVQVVEHAGDYEGAVAAGRAQAAQDPFSHFVDDERSLSLLLGYSAAALHLRQQLRDAGIVVDAQHPLFVYLPCGVGGAPAGITFGLRQVLGAHVHCFFAEPVQSPCFMVQMMAGQGAHPSVYDWGLTNRTEADGLAVPRASLPAAELMEPLLAGCFTVCDDTLFRQLVQVLDATGERIEPSAAAGLSGPGFLTGTETGRTWLHAQGLWPHLAQATHLVWTTGGLYVPPEAYARFEERGRALG
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: YXIT_BACSU
Sequence: MKWNNMLKAAGIAVLLFSVFAYAAPSLKAVQAKTPTVSTHTYKKIKELTYPQVHHVGNAAFEKKINQELKAYMNNRIRNT
What are the official names of this protein?
Uncharacterized protein YxiT.
Protein: LTC4S_RAT
Sequence: MKEETALLATVTLLGVLLQAYFSLQVISARRTFHVSPPLTSGPPEFERVFRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLFYLFARLRYFQGYARSAQHRLDPLYASARALWLLVAMAALGLLVHFLPGTLRAALFRWLQVLLPMA
What is the function of this protein?
Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4 with high specificity (PubMed:12445492).  Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions (By similarity).
What are the official names of this protein?
Leukotriene C4 synthase, LTC4 synthase, Glutathione S-transferase LTC4, Leukotriene-C(4) synthase.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Nucleus outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Protein: RL331_STAA9
Sequence: MRKIPLNCEACGNRNYNVPKQEGSATRLTLKKYCPKCNAHTIHKESK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS24_PYRAE
Sequence: MSAESFNIVHIRENKLLARRELLVEAVHQNASTPTRQSVREWVAKQLGIDISNVFVRRIKTEFGRGRSLAEVHVYNDSKIARVIEPLYILARNLGEEGKKLLEEAKKRRNERREKKKRKKK
What are the official names of this protein?
30S ribosomal protein S24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: BTGE_ASPCL
Sequence: MRGAFLATAAAIAGTAMADIAHMRRHGHDSFHQRRAVEQPAPEADATCGCTTEVVTSWGPPTLIPIATSSPSSTVTSEVVTTLHSTSYSTVTLVVTPSGASPNRESAPATPAVTLPTPGVTSFSTTGTYTIPATTLTVTHSTTVCGATTTELPSGTHTYGGVTTVVDRHTTVVCPYATVEPSGSTVTSVIRTTTYVCPSAGTYTIAPTTTYVPTSTVIVYPTPATITPGTYTQPAQTITVTRDNYIYVCPFTGQQLPTTAPVAPATTAVPATTTAVPATTTAVPATSSVAPSSSPSKPAAPSGAVSGQMGMTYSPYTNEGGCKDKASIISEVALLKSKGFTHVRVYSTDCGSLEFIGEAARTSGLRMIIGVFIKQSGVAGAQDQVTAISKWAQWDLVSLIVVGNESIQNHFCDASTLAGFIVSAKQSFKAAGYSGQVTTTEPINVWQANGDALCGAVDIIGANIHPFFNADVSAAEAGKFVAQEFKTLKGICPGKDVINLETGWPHSGEANGKAIPSREEQAIAIKAIADEVGSMSVFFSYFDDLWKQPGAFGVERYWGCIENF
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase btgE, Beta-D-glucoside glucohydrolase btgE, Cellobiase btgE, Gentiobiase btgE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Covalently-linked to the cell wall.
Protein: PETG_SYNE7
Sequence: MIEPLLCGIVLGLIPITLAGLFMAAYLQYRRGNQLGA
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: XYLA_RHIL3
Sequence: MSTGFFGDIQKVKYEGPDSTNPLAFRHYQPDEIVMGKRMEDHLRFAVAYWHTFTWPGGDPFGGQTFLRPWFEDTMKAAKLKADVAFEFFSLLGSPYYCFHDADVRPEGKTFAENTKNLNEIVDYFAEKQAATGTKLLWGTANLFSHRRYMSGAATNPDPDVFAFAAATVKTCIDATQKLGGENYVLWGGREGYETLLNTDIGRELDQLGRFLNLVVEYKHKIGYKGTILIEPKPQEPTKHQYDYDVATVYGFLKKHGLENEVKLNIEQGHAILAGHSFEHELALANALGIFGSIDMNRNDYQSGWDTDQFPNNVPEMALAYYHVLAGGGFKTGGTNFDSKLRRQSLDPADLLIGHIGGMDCCARGLKAAAKMIEDKALSQPLADRYAGWESAEAQKLFRGEYSLDEITHYVESHDVNPQPRSGKQELLENVVNRYV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECP_APICE
Sequence: MRFQVYILHLCFFILVVLTYLSQGQSYTTTTTTSTTEQPTFLQKIHETFKKVKENAKIHNLYIFDPPTWIYTTTTEKPVESTENFDITNRQLITVPVRCPPNYDFIKGRCREKIP
What is the function of this protein?
Serine protease inhibitor which exhibits antifibrinolytic, antielastolytic and antimicrobial activities (PubMed:27208884).  Displays antimicrobial activity against bacteria and fungi (PubMed:27208884).  Likely functions in the innate immune response to microbial infection and possibly in the venom, as an antifibrinolytic agent (PubMed:27208884).  The recombinant form inhibits trypsin (IC(50)=80. 02 nM, Ki=127. 25 nM), chymotrypsin (IC(50)=393. 78 nM, Ki=432. 59 nM), the microbial serine proteases subtilisin A (IC(50)=379. 20 nM, Ki=492. 77 nM) and proteinase K (IC(50)=189. 43 nM, Ki=271. 76 nM), plasmin (IC(50)=457. 98 nM, Ki=502. 91 nM), human elastase (IC(50)=347. 81 nM, Ki=469. 90 nM) and porcine elastase (IC(50)=94. 70 nM, Ki=125. 62 nM) (PubMed:27208884).  Does not inhibit thrombin (PubMed:27208884).  Binds to human plasmin and inhibits the plasmin-mediated degradation of fibrin to fibrin degradation products (PubMed:27208884).  Also binds to bacterial and fungal surfaces and exhibits antimicrobial activity against the Gram-positive bacteria B. thuringiensis (MIC=4. 21 uM) and P. larvae (MIC=11. 13 uM), the Gram-negative bacterium E. coli (MIC=6. 50 uM), and the fungus B. bassiana (IC(50)=2. 57 uM) (PubMed:27208884).  The synthetic peptide also exhibits antimicrobial activity against the Gram-positive bacterium P. larvae (MIC=41. 12 uM), the Gram-negative bacterium P. aeruginosa (MIC=65. 75 uM), and the fungus B. bassiana (IC(50)=44. 27 uM) (Ref. 2).  In vitro it does not induce an inflammatory response and has no cytotoxic activity against mouse embryo cells (Ref. 2).
What are the official names of this protein?
Secapin, AcSecapin-1.
What is the protein family that this protein belongs to?
Belongs to the secapin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YLAN_BACSU
Sequence: MASEMIVDHRQKAFELLKVDAEKILKLIRVQMDNLTMPQCPLYEEVLDTQMFGLSREIDFAVRLGLVDEKDGKDLLYTLERELSALHDAFTAK
What is the function of this protein?
Essential for cell growth and for normal cell shape.
What are the official names of this protein?
UPF0358 protein YlaN.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: Y1852_STAA1
Sequence: MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKGPFAPDFIKVWKERYKKIRQY
What are the official names of this protein?
UPF0374 protein SAHV_1852.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: FLGI_SHIDS
Sequence: MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATVLDARTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRSLNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: SIG16_HUMAN
Sequence: MLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVAMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVASLELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLRNGTSLRVLEGQSLRLVCVTHSSPPARLSWTWGEQTVGPSQPSDPGVLQLPRVQMEHEGEFTCHARHPLGSQRVSLSFSVHCKSGPMTGVVLVAVGEVAMKILLLCLCLILLRVRSCRRKAARAALGMEAADAVTD
What is the function of this protein?
Putative adhesion molecule that mediates sialic-acid dependent binding to cells.
What are the official names of this protein?
Sialic acid-binding Ig-like lectin 16, Siglec-16, Siglec-P16.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein.
Protein: EFTS_STAEQ
Sequence: MAISAKLVKELREKTGAGMMDCKKALTETDGDIDKAIDYLREKGIAKAAKKADRIAAEGLVHVEVKDNEAAIVEINSETDFVARNEGFQELVKEIANHILDSKVETVDALMESKLSSGKTVDERMKEAISTIGEKLSIRRFSIRTKTDNDAFGAYLHMGGRIGVLTVVEGTTDEEAAKDVAMHIAAINPKYVSSEQVSEEEINHEREVLKQQALNEGKPEKIVEKMVEGRLRKYLQEICAVDQNFVKNPDETVEAFLKAKGGKLTDFVRYEVGEGMEKREENFAEEVKGQMK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_ECO5E
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ULA1_CAEEL
Sequence: MLPFDPSTRYDRQVRLWGEEGQASIGSTSACVLGSDSLATEILKSLVLAGVQSFYVVDDAKVEQADIGQNFFLHADDIGRSRAEATLEKLTELNPSVSGSASSQPPTALAMEDVEKLTTFSVVVAANQNEEIDTTFAKVLYNIRVPFICIKTFGLIGTIRICIKEHTIANSHEENPRPDLRLDAPFSKLIEMINETNLDEMTLEQLRHTPYILLHFKALEVFRKQRNDPEAFPSTTAERKELQAILMSFRRSSEESGTKDSENFDEAKAAVIRAFQRTTIGSSVKSILSSPQCSTSTRPFWLICEALRRFVTENNNLLPLRGTLPDMTSDSSRYTRLATLFHEKALSDAQEVLRLTREVEKERGVGDVISDDVCYRFCKNADRIRVQYGDVLDYNEETKAIVEKIRESNIDEETRNQKVDEATWMLLMRAVGRFQKEKGRYPGTNGVPVSIDAQDLKKRVEVLIREALKDEQDFTSISNKVTDTAIAEICRFGAAELHVISSYVGGIAAQEIIKLATNQYVPIDNTFIFDGHTQESATFKF
What is the function of this protein?
Regulatory subunit of the dimeric uba-3-ula-1 E1 enzyme.  E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-rfl-1 (uba-3) thioester and free AMP.  E1 finally transfers NEDD8 to the catalytic cysteine of ubc-12 (PubMed:10993680).  Required for rfl-1 (uba-3) nuclear localization during early embryonic development (PubMed:19528325).
What are the official names of this protein?
NEDD8-activating enzyme E1 regulatory subunit, Ubiquitin-like activation protein 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
Protein: FPG_DESHY
Sequence: MPELPEVETIRRSLSQHILERRIEEILIRWPGAVEGYEEKTFADAVRGLKFQSIERRGKYLLFTLEEGWSFIAHMRMTGRMVYHAQSQEPEKHTHVVLKLSSGEIHFTDTRKFGRLQLVRTEERLQQPSLARLGPEPLEEGFSAAELGRRLAPRKLAIKAALLDQTLVAGIGNIYADEALFRAGIAPERCANSLTKEEIEKLYPAICQVLEEGIAANGTSFRDYQDANGERGDFQKELKVYGRGGEPCKECGHTLVRIRLAGRSTVFCPCCQV
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.