PharMolix/UniProtQA huggingface dataset:
Protein: NF40_NAEFO
Sequence: MKVYTDIFTRDEFLSDSYPM
What are the official names of this protein?
Unknown protein NF040 from 2D-PAGE.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
Protein: PROQ_SHIDS
Sequence: MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQKPVEKAPKTAKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CODY_BACCZ
Sequence: MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLFNITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAEEIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNDKFLHELAKLKTN
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TULP4_MOUSE
Sequence: MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFTSSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGILSMSWNYPIFLVEDSSESDTDSDDYSPPQDGPAAYPIPVQNTKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLAVAGMEQQAQLSELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMASGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVNKLTLPPRLCSYLSTAFIPTIKPPIPDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKLRPEFVIMDPRTDSKSDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRSSKSPKLPRISIEARKSPKLPRAAQEISRSPRLPMRKPSMGSPSLTRREFPFEDITQHNYLAQVTSNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNPNVFSEDEDDLPVTGASGVPENNPPCTVNIPIAPIHSSAQALSPTQSIGLVQSLLANQNVQLDVLTNQTTAVGSAEHAGDAATQYPVSSRYSNPGQVIFGGVEMGRIIQNPPQLPLPPPPPPPPQAPMQLSAVDHGDRDHEHLQKSAKALRPVPQLAAEGDAVVFSAPQEVQVAKMNPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTAAHYQPPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCTSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRSAAQRLDNSLIHATLRRNNREVALKMAQLADSSRAPLQPLAKPKGGAAGAVAQLPARPPPALYTCSQCSGAGPSSQSGAALAHAISTSPLASQSSYNLLSPPDTSRDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTMKRPPPYQWDPMLGEDVWVPQERTAQPTVPNPLKLSPLMLGQGQHLDVARVPFVPPKSPSSPTATFPTGYGMGMPYPGSYNNPSLPGVQAPCSPKDALSQAQFAQQESAVVLQPAYPPSLSYCTLPPTYPGSSTCSSVQLPPIALHPWNSYSTCPPMQNTQGTLPPKPHLVVEKPLVSPPPAELQSHMGTEVMVETADNFQEVLSLTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKDARTLSDFNSLISSPRLGREKKKVKSQKDQLKSKKLNKTNEFQDSSESEPELFISGDELMNQSQGSKKGWKSKRSLRTASELEEFKCRKASEKEDGRLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQVMQFGRIDGNAYILDFQYPFSAVQAFAVALANVTQRLK
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Tubby-related protein 4, Tubby superfamily protein, Tubby-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMBD1_NEOFI
Sequence: MPLPWISLIWFAYLIVITVLIVVASVFIHVYQTPRDRSSFVTFMCVFSIAALLATVMLLPVDVALVSSTTSSALGQRKEWATQEEVDKITYSLTVIYYSLYFLDALLCLVGIPFAYFWHEEYDEVAFEAGDQTPCKRFWAATKYTLAFIAVVIALVLVGFFAPMSESQPGHDLGYWRGFLIENRGEHAFTFLLGFVTTIGSCLYVFYTPSGLALLPALFLRRSYSFANQTLVGSTAMQLDFNRERQRQLEGRCGGNSALLSPKDRRELDTLVREERTLIRRQRLIEGRQEEDQSWPVTVYSKLKTILRPFRLLGGFSLFLVGLSTWISLLMTVIDKLINSPCKHHCGYVLSRTNFNPISWLLIQSSRAFPTDYIIFALIVFLFFWGSVVGVVAVGIRFLWIRIFQIRKGHTSPQAMLLATAMLTLITLGLNYSVVMMLAPRYATFGPQTFCDLAPTSSEEQPDCSNHWHLVKPCSEKADSTAADNTCTPSVASTILNRVALNFPLFGALLLWAHFLFLGIYLVILVASLVRSPRLDERQLDEDAEEAEEESLLASTGRSGNPT
What is the function of this protein?
Probable lysosomal cobalamin transporter.  Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity).
What are the official names of this protein?
Probable lysosomal cobalamin transporter.
What is the protein family that this protein belongs to?
Belongs to the LIMR family. LMBRD1 subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: IBTK_XENLA
Sequence: MERVWPECTTRCRSLQHALDVISVVTRASEQHIKVFLSSYCCNAVTLKDDFGRNATHIAASCGKKNVLDWLITGKGVDLAVKDKESGWTALHRSIFYGHIDCALSLLKHGSNLYIQDKDGYTPLDLVMKDRPPHIVFKTSDPTELYTWGDNVNFTLGHGTQQSKHHPELVEMFPRSGVYIKQMVLCKFHSVFLSQKGQVYTCGHGQGGRLGHGDELTCLVPRLVEGLRGHPCTQVAGAKDHTVVLTEDGYVYTFGLNTFHQLGIQPPPPNSNVPRQIQAKTMKGKTVLGVAAGRFHTVLWTKDAVYTVGLNGGQLGYLQDPNGEKFVSCPRQVSALHHKDINITLVSASDGATVCVSERGDIYLLSEYQCKKLASKQLNLKKVLVSGGILEHKAAPEHLKENGGQPASVFALDQAGRVFCWKSPGSSLKQCWWVYGRQLFMSDVALNKNEIMFVTQDGEGFTGKWMLEKKKKENTISNIMCHSDSQNVYEKISMQKLPFVHRAVSVATDPSGCNFAVLQSDPKTSLFEVPSVSSSVFAEDFEKLLNEANETDSIHDVTFQVGTKIFPAHKYILALRCDFFSKLFSSGEINSLDFPEVHQKGEDAAGCDLFVIEKIPPELFSHVLQFIYSDTCDMLLQGHKPKLWHKEENENTIICNFQKMGFREDIEGKSAYEVYKNSRICAENEKQKGKTKQSKKTRSIGDETSPVKMLQNTAKKFGLSNLSSRLDGVRYENGRINVFHKKSENKLRFNQKKCSSHYDVMMKSEDGKEFHCHKCVLCARLEYFNSMLSSSWIEASCCSQLEMPIHSDVLQVILDYIYTDEVLTVKESANVEFVCNVLVIADQLLIVRLKEICEVTIAERITLKNAAELLEFAALYNADQLKLSCLQFVGLNMGALLEARSLDVLSDDVLKDLSEAYRKMIPSMNKRIITPYLDGPDISILQSEDIESLISVQDDIYSYQITQEATLKKSKAKPKKKQRKRLDSSGGYNLSDIIQSPTSTGFVKPEKTNSVESLQDLLTSDSEGSFVGASSPRDLQSPDLFPVFTHETKETICVERNRSSPPVANGAASTKMPIPTTSSPKAIPMSRITPSTSPNWVAMPCSPASPVTMDLRAIMELEENIQKCGAMPKLNAGGTKPGTHVMKLSQKQRKMMAMSSKESNNENKPAKVTVAPTTIKSPAKTWAAAFHLGENKSFRDLLLEEKQSVTSFPSLSSDVKKSKHTEELDPSELARRPSGTLNQEAKLKCDVPNQDNSNPWHLTLSKNNASSAPVTFTAIVEEEEKQEAALIRSREKPLALIQIEERAIQDLLLHYQAIDNPEEYITIERAAQIPMATPMWNKH
What is the function of this protein?
Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development.
What are the official names of this protein?
Inhibitor of Bruton tyrosine kinase, IBtk.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: HIS8_STACT
Sequence: MKEQIQQLSAYQPGLSPRALKKEFGLDIDLHKLASNENLYGPSPKAKEAIKEHVDEVLYYPETGAPTLRKKIADTLNIDENRILFGAGLDEVILMISRAVLTPGDKIVTSQATFGQYYHNAIVESAEVVQVPLKENGQFDLDGILNEIDEDTALVWICNPNNPTGTYVTHEELEAFLEKVPSNVPVLVDEAYFEFVTADDFPDTLKLQEKFPNAFLMRTFSKAYGLAGLRVGYVIATKEAIHNYNIIRPPFNVGRLSEYAAVAAFEDQDYLKEIQKRNAEERAKFFEIPESKHFFDSQTNFIFVNTKRPKELYEALLKVGCITREFPIGVRITIGFPEQNDKMIEVLKNFDFEA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: TET3A_XENLA
Sequence: MMETQPTSLPHVLPQDVYEFCDDRKSLGRLRVSEMPAESNGDGGGSKGDGAAVVAKEVPEQSNKKRKRCGVCVPCLRKEPCGACYNCVNRSTSHQICKMRKCEQLKKKRVVPLKGVEAVNKDDSKNQAKEQVPNVKNCSESILVDGPKTDQMEAGPVNHVQEGRLKKECDSTLPSKACEDLANQLLMEANSWLSNTAAPQDPCNKLNWDKPTIPNHTAATNNSNLEDAKNLVAFSAVAEAMSNYGMPASGTPSSVSMQLYEKFNYETNRDSSGHPEGNAPSCPEDLNTLKTALALAKHGVKPPNCNCDGPECPDYLEWLENKIKSSQKDSQESSFPGLGQVSKELVQKSYPKEEVLNLENKNLCPSGNLPFSQNALSLAKEKNISLQTAIAIEALTQLSSALPQTNNECPNSSSQPLINTCDQLTHFPTAKGNQLPIFPMACNELFQNQQSQLYTGKNALPVPQSPRQTSWEQNKKPSYQEGQYIPENLSQSSSVLPSDASTPQKTEFLQQWIQNADLLKSPSDPMTGLKQLLGNTDEYIKSVFKGPEALPNKIKHVKTKRTIKSIKKKSSDFLKMSPDQQLSQLLQENDFHHNAQAALQQHLHHKRNLFVDPNTMEACAQEQQNWWVPKSQKLPVSKTTENPVKERKKRRQRSPSQKQVEPKPKPPRKQVQIKKPRMKEGNAVFMPVSQISLDAFRGAEKEENQLKEMNLEKSLSNNIQPDLLESQSILVTGSQANIENRKTVNTQETCNENQASNGKASNFALCVNQANSLGAKDSCPTPSTDDASSSSGQGDSANQHTNVGDVPGQNDLSCLDDKFEDLLRQFEAEFGEDFSLPGSEAPSQNGVGPPKQQISGDPQFKMPFPSQLLPSENSTRPDAHSNPALSNNPISHNVSHNLDSLFSSKSPKKIKIESSGAITVVSTTCFYSEENQHLDGTPTKSDLPFNPTLSGFLESPLKYLTSPTKSLIDTPAKMAQAEFPTCDCVEQINEKDEGPYYTHLGSGPTVASIRELMEDRFGEKGEAIRIEKVIYTGKEGKSSRGCPIAKWVIRRQSEDEKLMCLVRQRAGHHCENAVIIILIMAWEGIPRALGDSLYSDITETITKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFRLIGDNPKEEEFLNDNFQDLATKVAPVYQMLAPQSYENQVNNEEVAIDCRLGLKEGRPFSGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRTIGRIPEDEQLHVLPLYKVSSTDEFGSEDGQAEKIRKGGIQVLASFPREVRKLSEPAKSCRQRQLDAKKAAAEKKKLQKEKLVSPDKTKQEPADTKMCQQNPGVPQQQTKPCVKVEPSNHYNTYKYNGNGVVESYSVLGSCRPSDPYSMNSVYSYHSFYAQPNLPSVNGFHSKFALPPFGFYGFPNNPVVPNQFMNYGTSDARNSGWMNNSFEKKPDVQSLADGMNQSYGSELPEQSYRRSSEVPHHYSLQNPNSQKSFNISHRTTPSPMETTPYSNLPCYNKVIKKEPVCDPLVDPFQRANSVHSQSPGVNHSLQTSDLPFKANGALPSSGRSNAEGPCSMSLPNDKSGLEKRDYFGVHSNVPALKDKQWTPYGTDVPVGQRDSLDAQSPGKVWSSCKLSDSPAVLPSFASTQTKNWNGRQASLNQGLKEPMPFQEKLWNSVAASDRCSVTPSDRSSVTPCAELQDKNWASFPNPVGNSLKTESSQNHWDPYSLDDNMDDGQSKSVKEEEDEEEIWSDSEHNFLDKNIGGVAVAPGHGSILIECARRELHATTPLKKPNRCHPARISLVFYQHKNLNQPNHGLALWEAKMKLLAERARVKEEEAARLGIKQEVKSLGKKRKWGGAATTETPPVEKKDFIPTRQATTILTDSATTAFSYAYTKVTGPYSRFI
What is the function of this protein?
Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.  Conversion of 5mC into 5hmC probably constitutes the first step in cytosine demethylation.  Selectively binds to the promoter region of target genes and contributes to regulate the expression of numerous developmental genes, including pax6, rax, sox9 and six3.  May also contribute to the regulation of target genes in ways that do not require its enzyme activity.
What are the official names of this protein?
Methylcytosine dioxygenase tet3-A.
What is the protein family that this protein belongs to?
Belongs to the TET family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Detected on chromatin, where it binds to target gene promoters.
Protein: CYSN_LARHH
Sequence: MTHQSDLIAEDIHAYLARHETKDLLRFITCGSVDDGKSTLIGRLLHDSRLIFEDQLAAIERDSQKHNTTDEAVDLALLVDGLQAEREQGITIDVAYRYFSTDTRKFIIADCPGHEQYTRNMATGASTADLAIILIDARYGVQTQTRRHSFIASLLGIRHVIVAVNKMDLLEFDQAVFERIRQDYLTFAKALDIHDIRFVPLSALRGDNVVSPSERMPWYDGPSLMQLLDSIRLDADQALQAFRLPVQYVNRPNLDFRGFCGTIAAGVIRPGDQVTVLPSGRQSRVRAIVTTDGELPVAATGQAVTLTLEDEIDISRGDMIVRHGEPLPLVADRLTVELVWMHDAPLQTGRAYWVKLAGKWLPGRVTAVHHRVNVNTMEREAASSLALNEIAEVTLEIDAPMAVDAYRQCRATGSLILVDRISNATLGAGMIRSAEPSAGIQSEKDAARRWQAFEIEFNELVRRHFPHWQARDMRDWPGHKE
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: PER32_ARATH
Sequence: MNFSYSSLSTWTTLMTLGCLLLHSSISSAQLTPTFYDNTCPSVFTIVRDTIVNELRSDPRIAASILRLHFHDCFVNGCDASILLDNTTSFRTEKDAAPNANSARGFPVIDRMKAAVETACPRTVSCADILTIAAQQAVNLAGGPSWRVPLGRRDSLQAFFALANTNLPAPFFTLPQLKASFQNVGLDRPSDLVALSGGHTFGKNQCQFIMDRLYNFSNTGLPDPTLNTTYLQTLRGQCPRNGNQTVLVDFDLRTPTVFDNKYYVNLKELKGLIQTDQELFSSPNATDTIPLVREYADGTQKFFNAFVEAMNRMGNITPLTGTQGQIRQNCRVVNSNSLLHDVVEIVDFVSSM
What is the function of this protein?
Exhibits a Ca(2+)-pectate binding affinity which could be interpreted in vivo as a specificity to interact with the pectic structure of the cell wall.
What are the official names of this protein?
Peroxidase 32, Atperox P32, ATP16a, PRXR3.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted. Vacuole. Note=Carboxy-terminal extension appears to target the protein to vacuoles.
Protein: RMD5A_MOUSE
Sequence: MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLVLTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.  MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex.  Catalytic activity of the complex is required for normal cell proliferation.  The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.
What are the official names of this protein?
E3 ubiquitin-protein ligase RMND5A, Protein RMD5 homolog A.
Protein: TGT_YERPN
Sequence: MKYELQKTDGRARRGRLVFERGVVETPAFMPVGTYGTVKGMTPEEVKETGAQILLGNTFHLWLRPGQEIMKLHGDLHDFMQWHGPILTDSGGFQVFSLGAMRKIKEEGVHFKNPINGDSVFLSPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAARSRQRFDELNNKNALFGIIQGGVYEDLRDVSVKGLVDIGFDGYAVGGLAVGEPKEDMHRILEHVCPQIPEDKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKDDTATLDEHCDCYTCRHYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRQAIEEGKLEHFVEDFYGRIGKPVPPLNV
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RS3_SALA4
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MINC_BLOFL
Sequence: MLESVSVDLQGNNFTLLVIQTHTTCTSQIQLELTQKIKNSPSFFSNNTPVVINVENINHHDDWFNLYQTISNIGLFIIGVCCCYNKKLKNIITQSGLPILTKGNIIKSHKNTIKTNYTKPTFDDKTNAISKTQTIHTPIRSGQRIYARNRDLIIISNVSSGAEVIADGNIHIYGSVRGRVLAGASGCEQSQIFCTKLSPELISIGGYYWLNDQIPPEFLGKSARFYLQNHTLIIQHIS
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: DLGD_KLEP3
Sequence: MKVTFSQLKEAFNQVLLKRGVAAETADACADMFARTTESGVYSHGVNRFPRFIQQLDNGDIIPEAKPQRITSLGAIEQWDAQRSIGNLTAKKMMDRAMELASDHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRELPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGLSIVLDMIATLLSNGSSVAEVTQENSDEYGVSQIFIAIEVDKLIDGATRDAKLQRIMDFITTAERADENVAVRLPGHEFTRLLEENRRDGITVDDSVWAKIQAL
What is the function of this protein?
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
What are the official names of this protein?
2,3-diketo-L-gulonate reductase, 2,3-DKG reductase, 3-dehydro-L-gulonate 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_I18A0
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILKEESDEALKMTIASVPASRYLTDMTLEEMSRDWFMLMPKQKVAGSLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAVGVLIGGLEWNDNTVRVSETLQRFAWRSSNENGRPPLPPKQKRKMARTIKSEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: RL13_PSEPF
Sequence: MKTFTAKPETVKRDWFVVDAAGQTLGRLATEIASRLRGKHKPEYTPHVDTGDYIVVINAEQIRVTGAKTTDKMYYSHSGFPGGIKSINFEKLIAKAPERVIETAVKGMLPKNPLGRDMYRKLKVYAGAAHPHTAQQPQELKI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: Y1855_STAHJ
Sequence: MEYQYPLDLDWSNEEMVDVIAFFNKIENYYENSVNGQDLMNHYKRFKEIVPSKAEEKQLFKEFEEKSNYNSYKVVQEVKNNPELTSFSAK
What are the official names of this protein?
UPF0223 protein SH1855.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: SEC8_ARATH
Sequence: MGIFNGLPVPSDKTYLREELARIDESWAAARFDSLPHVVHILTSKDREADIHILKEQSDVVEEVVDEVVHAYHGGFNKAIQNYSQILRLFSESTEKIGDLKHDLAEAKQSLGARNKQLHQLWYRSVTLRHIISLLDQIEGIAKVPSRIEKLIADKQFYAAIQVYLQSSLMLEREGLQTVGALQDVRSELTKLRGALFFKILDDLHAHLYNRGEYSSVASSIYERDDEVPTTTAVAASRMSSQPLSRRTRTLKGDSQFGVRGLTNGSYRTASNDESSSFDGHDEEDSVEHDESTADTARNGTDSKLLSHQLPPWLSDSTPDEFIEAVRKSDDPLHVKYLQTLVQCLCMLGKVAAAGAIICQKLRPTIHEIIISKIKAHLETTNLSKSACSQGDRSVAAGLHLIKGQSEAYRLSKEKPQNGISNSGTHLAVSPVSPLMAPGGKAQAAAKELLDSILDTIVKIFENHVVIGELLEMKASQHDINTPRSLPTDVNWNTESEASQATGGYTISFPLTVLQSECQQLICEILRATPEAASADAAAQTAKLAKKAPKKDKRDAPEDGLTFTFRFTDATVSISNQGADLIRQGWGKRAPNASLEGYGSAAVLPEQGIYLAASIYRPVLQFTDKITSMLPKKHSQLVNDGLLTFTENFVKDHLLPTMFVDYRKGVQQAISSAAAFRPRAHTTTYTATVEKGRPILQGLLAIDLLAKEVLGWAQAMPKFATDLVKYVQTFLERTFERCRTSYMEAVLEKLSYMLIGRHDIEKLMRLDAASACLPSTLGHAVSHSEAVGTEVELSDLFLSLRPIKQDNLIRDDNKLILLASLSDSLEYVADSIERLGQAVPRVASQAEGNSRNQAASPRNLASFADEYRKLATDCLKVLRVEMQLETVFHLQEMTNREYLEDEDAEEPDDFVISLTSQITRREEGMAPFISGEKRNYVFGGISGIAANASIKALADMRSINLFGVQQICRNTIAVEQAMAAIPYIDGETVQQNLDRVRTYFELLNMPFEALLAFIAEHDQMFTPTEYSNLLKVNVPGRDTPSDAQSRLLEILSH
What is the function of this protein?
Participates in polarized pectin delivery required for the polarized development of the mucilage-producing volcano cells of the seed coat.
What are the official names of this protein?
Exocyst complex component SEC8, AtSec8, Exocyst complex component 4.
What is the protein family that this protein belongs to?
Belongs to the SEC8 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, phragmoplast. Secreted, cell wall. Secreted, extracellular exosome. Note=During cytokinesis, localizes to the nascent cell plate and later to the cell plate insertion site and along the post-cytokinetic wall (PubMed:20870962). Shuttles from the cytoplasm to the exocyst-positive organelle (EXPO) in the presence of EXO70E2 (PubMed:24307681).
Protein: YBEY_PSE14
Sequence: MLELDLQIASETSAPDEARFRLWCEMGLRQRSADSELTIRLVDENEGRELNHTWRHKNYATNVLSFPADAPDDMLDIPLLGDLVICVPVVNREAAEQGKSVDAHWAHMVIHGCLHLLGYDHIDDEEAEEMEALERTLLEELGYPDPYAEDESADHPHSDTPSKDHE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_RHIL3
Sequence: MSENIAVVGSGAFGTALAAVIALAGRSAVTLVGRDPSLIADLKAERLHDAVLPGILLPDTLEFSAEADAITGASIVLFAMPSQAQADAARQYGPYLCKDAVVVTCAKGIERATGNLLTDMLERELPDHSIAVLSGPGFAADIAKGLPTAMAIAAADMETAERLAQAISGRTFRLYASNDRIGVQLGGALKNVLAIACGIVEGRGIGDSARAALIARGLAEMSRFVVAKGGQADTVRGLSGLGDLVLTATSHQSRNLRFGIALGRGEKTDPLQGALVEGAFAASVASRLAAELKVSMPITDAVSAIIDGKLDISEAIEQLMTRPITTE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_ECOLI
Sequence: MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor RF1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.