PharMolix/UniProtQA huggingface dataset:
Protein: TATA_SYNAS
Sequence: MFGIGMPEMLIILVIILIIFGAGKLPEIGGAIGKGIKNFKKASNESEEIDENSRPKKIEPK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HBA_LAMGL
Sequence: VLSSKDKANIKTAFGKIGGHAADYGAEALERMFLGFPTTKTYFPHFDLSHGSAQVKAHGKKVGDALTKAADHLDDLPSALSALSDLHAHKLRVDPVNFKLLSHCLLVTVAAHHPGDFTPAVDASLDKFLANVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SOX10_XENTR
Sequence: MSDDQSLSEVEMSPVGSEDPSLTPDPLPPHAHSSPDDDEETKVKKEQDSEDERFPVCIREAVSQVLSGYDWTLVPMPVRVNGGSKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNENDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKPNPGEGDGSSEAEGGAASIQAHYKNSHLDHRHGSPMSDGNSEHSAGQSHGPPTPPTTPKTELQAGKSDGKRDGSRSLGEGGKPHIDFGNVDIGEISHDVMANMETFDVNEFDQYLPPNGHAGHPSHIGGYTSSYGLSGALAAGPSAWALAKQHPQTDSKAQVKTESSSTSHYTEQPSTSQLTYTSLGLPHYGSAFPSISRPQFDYADHQPSSSYYSHSSQASSLYSAFSYMGPPQRPLYTAISDSPSVAQSHSPTHWEQPVYTTLSRP
What is the function of this protein?
Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox8 and sox9 to induce neural crest progenitors.  Acts downstream of wnt-signaling at the neural plate border.  Involved in the specification of neural crest progenitors fated to form the pigment cell lineage (By similarity).
What are the official names of this protein?
Transcription factor Sox-10, SRY (sex determining region Y)-box 10.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PURL_THEFY
Sequence: MSEEPRFDTVAKAAATPDLPQPYTELGMKDEEYARVREILGRRPTSAELAIYSVMWSEHCSYKSSKVHLRQFGEKAPDTDVLLVGIGENAGVVDVGDGYAVTFKIESHNHPSYVEPHQGAATGVGGIVRDILSMGARPVAVMDSLRFGPADAPDTQRVLPGVVSGISSYGNCLGLPNIGGEVGFDAGYASNPLVNALCVGVLKHENIKLAQASGPGNHVVLFGAATGPDGIGGASVLASASFDEESQAKRPSVQVGDPFLEKLLIECCMELYAKDLVVGIQDLGAAGVSCATTELAAGGTGGMRIELDRVPLRDPRLTPEEILMSESQERMMAIVEPDKLDEFLAVCAKWDILASVIGEVTDVTPEEEARGGRLVMTWRGETIVDLPPRTAADQGPVYHRPIERPADQDALLADDPAALPRPSSDEELRDQVLRVLAAPGICDSSWITDQYDRYVMGNTVLAMPHDSGMIRIAEDTDRGVALATDGNGRYTRLDPYVGTQLAYAEAYRNVAATGARPLAVTNCLNFGSPEDPGVMWQFAEATRGLADACQALGTPVTGGNVSFYNQTGSTAINPTPVIGVLGVIDDVHKRVTSAFSAEGESVVFLLGETRLELGGSAWADVIHGHLGGRPPQIDLDAEAALGRVLIDGAAAELLVSAHDLSDGGLAVALAESCLRGGVGCEVDLGDDAFTALFSESAARAVVSVRPEHETALVDLCAKHGVPVRRLGTVGGSALTMVHRTGRISIEVAELRDAYESTLPALFGNK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLH1_YEAS8
Sequence: MLPTSVSRSLYLKTFRSHLLRAPQIVLKRMSSSIDISKINSWNKEFQSDLTHQLATTVLKNYNADDALLNKTRLQKQDNRVFNTVVSTDSTPVTNQKSSGRCWLFAATNQLRLNVLSELNLKEFELSQAYLFFYDKLEKANYFLDQIVSSADQDIDSRLVQYLLAAPTEDGGQYSMFLNLVKKYGLIPKDLYGDLPYSTTASRKWNSLLTTKLREFAETLRTALKERSADDSIIVTLREQMQREIFRLMSLFMDIPPVQPNEQFTWEYVDKDKKIHTIKSTPLEFASKYAKLDPSTPVSLINDPRHPYGKLIKIDRLGNVLGGDAVIYLNVDNETLSKLVVKRLQNNKAVFFGSHTPKFMDKKTGVMDIELWNYPAIGYNLPQQKASRIRYHESLMTHAMLITGCHVDETSKLPLRYRVENSWGKDSGKDGLYVMTQKYFEEYCFQIVVDINELPKELASKFTSGKEEPIVLPIWDPMGALAK
What is the function of this protein?
The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells.  Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid.  Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin.  Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.  Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities (By similarity).
What are the official names of this protein?
Cysteine proteinase 1, mitochondrial, Bleomycin hydrolase, BLM hydrolase, Homocysteine-thiolactonase, HTLase, Hcy-thiolactonase, Leucine aminopeptidase 3, Y3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm.
Protein: Y1554_NEIM0
Sequence: MSIQSGEILETVKMVADQNFDVRTITIGIDLHDCISTDIDVLNQNIYNKITTVGKDLVATAKYLSAKYGVPIVNQRISVTPIAQIAAASKADSYVSVAQTLDKAAKAIGVSFIGGFSALVQKGMSPSDEVLIRSIPEAMKTTDIVCSSINVGSTRAGINMDAVKLAGETIKRTAEITPEGFGCAKIVVFCNAVEDNPFMAGAFHGSGEADAVINVGVSGPGVVKAALENSDATTLTEVAEVVKKTAFKITRVGELIGREASKMLNIPFGILDLSLAPTPAVGDSVARILEEMGLSVCGTHGTTAALALLNDAVKKGGMMASGSVGGLSGAFIPVSEDEGMIAAAEAGVLTLDKLEAMTAVCSVGLDMIAVPGDTPAHTISGIIADEAAIGMINSKTTAVRIIPVTGKTVGDSVEFGGLLGYAPVMPVKEGSCEVFVNRGGRIPAPVQSMKN
What are the official names of this protein?
UPF0210 protein NMCC_1554.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: PPNP_BURCJ
Sequence: MTSATQFDNVSVVKRANVYFDGKCVSHTVLFPDGTRKTLGVILPCALNFGTDAPELMEVQAGKCRVKLDGSSEWQTYGAGESFSVPGKSRFDIEVLETLDYVCSYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: HEMTB_AQUAE
Sequence: MLIRPNKVQKVGNLFMDTVHEEEIRLLNQLYDTLMKKDVEKADQLMDELLVDLEDHFTTEEELMREFEFFAYPMHKAEHDTMRKRFKEVYDKWKKEKNPEEVVRFLKEEFVPWLKSHVARWDSTTAQQLGD
What is the function of this protein?
Oxygen-binding protein.  May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes.  The oxygen-binding site contains two iron atoms.
What are the official names of this protein?
Bacteriohemerythrin.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: RL1_SELRU
Sequence: MAKAGKKYQDACKLVEAGKFYTAAEAMELVKKTATKKFDETIELHVRLGVDPKYADQQVRGAMVLPHGTGKSKRVLVFAKGEKVKEAEAAGADFVGSDEIVQKIQGGWLDFDVAVATPDMMGTVGRLGKVLGPRGLMPNPKLGTVTMDLTKAVSEIKAGKVEYRTDKAGNVHCPIGKASFDAEKLQQNFQALIDTLNRVKPAAAKGQYMRSITVSATMGPGIPVQL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: AGT2L_CAEEL
Sequence: MSTLVNALGFFTSSTPAAAATKDVRSKEEILKRRKDTIGSKCQIFYSDDPFMVSRASMQYLYDEKSNKFLDCISNVQHVGHCHPKVVEAISKQLATSTCNVRFVSTQLTDCAEQILSTLPGLDTVLFCNSGSEANDLALRLARDYTKHKDAIVIEHAYHGHVTTTMELSPYKFDHGSTVSQPDWVHVAPCPDVFRGKHRLADNELTNEDKLYAAGKQYSDDVKSILNDVESRQCGVAAYFAEALQSCGGQVIPPKDYFKDVATHVRNHGGLMIIDEVQTGFGRIGRKYWAHQLYDDGFLPDIVTMGKPMGNGFPVSAVATRKEIADALGGEVGYFNTYGGNPVACAAVISVMKVVKDENLLEHSQQMGEKLEVALRDLQKKHECIGDIRGVGLFWGIDLVKDRNTREPDQKLAIATILALRKSYGILLNADGPHTNILKIKPPLCFNENNILETVTALDQVLTLMNR
What are the official names of this protein?
Ethanolamine-phosphate phospho-lyase homolog 1, Alanine--glyoxylate aminotransferase 2-like.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: MRAZ_STAAB
Sequence: MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RSMC_YERPB
Sequence: MSALTPASEVILRHSDEFIARHVLFAGDLQDALPAQFDAAGVRVHTNQYHHWQLLSNTLEENVQFGLLATAETLAACDTLIYYWPKSKQEAQFQLANLLSILPVGTDIFVVGENRSGVRSAEEMLADFAQLAKIDSARRCGLYHGRLDKQPEFDADAWWESYQVGSVTVKTLPGVFSRDSLDSGSHLLLSTFNEPFKGSVLDVGCGAGVLASVLAQQSPKIKWTLSDVSAAAIEASRATLAVNNIEAQVIASNVYSDIKGRFEMIISNPPFHDGIQTSLTAAEMLIRGATAHLHVGGKLRIVANSFLPYPALLDAAFGSHEVLAQNGRFKVYQATVGRPPRDPKKKR
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSD_ECO24
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIVEGHELSSVFFYREGVYNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGIVDETEAGRLGLASSNLQPGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSQ_ACISD
Sequence: MAQLPASMRRKRAAITSIHDKPPTRKQKLANAGGWVLLVIAFVVLAVGIYGLYKVITDATVAKLEVVGSTSSVETQQVMQHVAPIIKANYFTSDLEQIRDKTLEISWVDRVVVSRAWPNGIRVRVMPRHAIARWGTGRLLSDGGDVFSEAEPTIHPELPLLHGPVSQSKMMMRRYNEINQLFHPANLRLKELYLTERMTWFMQFDSGLRIIVDQDQTMNKLQRLSHLAQSDLKPVWSKISAIDLRYRNGLSIQWKNATPPKIVNGQFVVTIDDTSIAGGTKAKP
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.  May control correct divisome assembly.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: MNMG_ECO7I
Sequence: MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREASGEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_LEGPA
Sequence: MPYIPHTPNDTKEMLTAVGAQDIQDLFDEIPASLQYAGFQSIPAGINEMEMLKEAQNQAQKNRNGICFIGAGCYEHHIPAAVWDIASRGEFLTAYTPYQAEASQGTLQLLYEYQTMICELTGMEVSNASMYDGATALAEAVLMAVRLNKHSKTNRVLITGTVHPFYRETIETIVRNQHIEVITLPFDEQQGITDFGSLNQYTGEDITALVIAQPNFFGCLEQVDKMTSWAHHNKTISVACVNPTSLALLKPPCSWGEHGVEIVCGEGQPLGSPMASGGPYFGFLSTRMAHVRQMPGRIIGRTVDKDGKTGFSLTLQAREQHIRRAKATSNICTNQGLLVTAATIYMSLLGPEGLSQVATQCHQNTHELITALTQIEGVELAFKAPFFHEALIKLNQPVQSVLQQLADAGIAGGYAPEQHYPQLANTLLVCATEVRSAEDIAKYAKTLKTIMSKRGA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: MRAY_ARTS2
Sequence: MIALLIGAGLALLFALVGTPLFIRLLVRKSYGQFIRDDGPTSHHTKRGTPTMGGTVVVFAVLLSYALTHLIMWMMNPRSPGPSASALLLLFLMVGMGLVGFLDDFIKISKQRSLGLDAKAKLVLQGAVGIIFAILALNFPNADGVTPASTQISLVRDIPWLNLAFGGTVLGAILFVLWSNLIVTAATNGVNLTDGLDGLAAGASVMVFGAYTLMGIWQSNQACGSPRQTGGGCYSVRDPLDLALLAAILSAALVGFLWWNTSPAKIFMGDTGSLAIGGAVAGFAILSRTELLLAFIGGLFVLITLSVIIQVGYFKITKGKRFFKMAPLQHHFELKGWAEVTVVVRFWILGGLFVAAGLGIFYAEWVVLL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SKL1_ARATH
Sequence: MEIFSASASLTLTGFVPRLLPLLSPQARTTLCKPLLSSSSTRLISCHSRIAPSRSLADQSASTGISVVDSDPIDVVKRKAMDIAPELKGASIFLVGINNSIKTNTGKLLAEALRYYYFDSDNLITEAAGGNVSAQALKEADEKAFQESETEVLKQLSSMGRLVVCAGDGAVQSLRNLALLRHGISIWIDVPLDITAKGDDDSFHSEPSPELFDTLKASYEKSRKGYETADVSISLEKIATKLEFEDLEAVTSEDIALEILKEIEKLTRVKKMMEEASRPF
What is the function of this protein?
Required for chloroplast biogenesis.
What are the official names of this protein?
Probable inactive shikimate kinase like 1, chloroplastic, AtSKL1.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS9_NITHX
Sequence: MSDTMQSLDQLSALKTAESEAPKHTKKIDKYGRAYATGKRKDAVARVWIKPGAGKILVNAREVEVYFARPVLRMMIQQPLVAAARAGQYDVVCTVAGGGLSGQAGAVRHGLSKALTNFEPELRGVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: Y1312_METJA
Sequence: MTIAFGPVPSRRLGKSLGINSIPCKFCSYDCVYCQVGRTINKTIERREFYSPEDIFKSVEERIGKLNNEKIDYLTFVADGEPTLDINLSKEVEMLRDFDIPIAIITNSSLIWREDVRNDILNFDLVSFKVDSVDEKIWREINRPHKDLVLDKILEGMIAFRDNYKGELITETMILGSIKYTEESIIKTAEFLKELNPNKCYLNTPIRPPSEKYIKPPKIEVITKILAIFNEIIGKNKIKLLGKFEGNEFIFSENVEEDILAITSVHPMREEVIKELLNKSNISFDIINKMVNEGKLIKLEYDGKVFYMKNIKSRDKNVSNP
What are the official names of this protein?
UPF0026 protein MJ1312.
What is the protein family that this protein belongs to?
Belongs to the UPF0026 family.
Protein: PARD3_RAT
Sequence: MKVTVCFGRTRVVVPCGDGRMKVFSLIQQAVTRYRKAVAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFRPYQTTSEIEVTPSVLRANMPLHVRRSSDPALTGLSTSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTTGSPKTCDRKKDENYRSLPRDPSSWSNQFQRDNARSSLSASHPMVDRWLEKQEQDEEGTEEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFHVVPAANKEQYEQLSQREMNNYSPGRFSPDSHCVANRSVANNAPQALPRAPRLSQPPEQLDAHPRLPHSAHASTKPPTAPALAPPNVLSTSVGSVYNTKRVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHPREMNAEPSQMQSPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETLRRSMSTEGNKRGMIQLIVARRISRCNELRSPGSPAAPELPIETELDDRERRISHSLYSGIEGLDESPTRNAALSRIMGESGKCQLSPTVNMPHDDTVMIEDDRLPVLPPHLSDQSSSSSHDDVGFIMTEAGTWAKATISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSNASQLDFVKTRKSKSMDLGIADETKLNTVDDQRAGSPNRDVGPSLGLKKSSSLESLQTAVAEVTLNGNIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPMVDDDDEGMETLEEDTEESSRSGRESVSTSSDQPSYSLERQMNGDPEKRDKAEKKKDKAGKDKKKDREKEKDKLKAKKGMLKGLGDMFRFGKHRKDDKMEKMGRIKIQDSFTSEEDRVRMKEEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELLYGGMSSYDGCLALNARPQSPREGHLMDTLYAQVKKPRSSKPGDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQSWSSSRPASQSGRHSVSVEVQVQRQRQEERESFQQAQRQYSSLPRQSRKNASSVSQDSWEQNYAPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQLKKQPPADGVRGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS
What is the function of this protein?
Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:18550519).  Seems to play a central role in the formation of epithelial tight junctions (By similarity).  Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity).  The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (By similarity).  Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (By similarity).  Involved in Schwann cell peripheral myelination (PubMed:21949390).  Targets the phosphatase PTEN to cell junctions (PubMed:18082612).
What are the official names of this protein?
Partitioning defective 3 homolog, PAR-3, PARD-3, Atypical PKC isotype-specific-interacting protein, ASIP, Atypical PKC-specific-binding protein, ASBP.
What is the protein family that this protein belongs to?
Belongs to the PAR3 family.
What are the subcellular locations of this protein?
Cytoplasm. Endomembrane system. Cell junction. Cell junction, tight junction. Cell junction, adherens junction. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell membrane. Note=Localized along the cell-cell contact region. Colocalizes with PARD6A and PRKCI at epithelial tight junctions. Colocalizes with the cortical actin that overlays the meiotic spindle during metaphase I and metaphase II. Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction. Colocalized with SIRT2 in internode region of myelin sheat (By similarity).
Protein: ADDA_PONAB
Sequence: MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQARTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFTSDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPYPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAAEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSES
What is the function of this protein?
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network.  Binds to calmodulin (By similarity).
What are the official names of this protein?
Alpha-adducin, Erythrocyte adducin subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. Adducin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNZ1_MOUSE
Sequence: MSMDVTFLGTGAAYPSPTRGASAVVLRCEGECWLFDCGEGTQTQLMKSQLKAGRITKIFITHLHGDHFFGLPGLLCTISLQSGSVVARQPIEIYGPVGLRDFIWRTMELSHTELVFPYVVHELVPTADQCPVEELREFAHMDETDSSPKGQGRTILLDAEENSYCLVDDEQFVVKAFRLFHRIPSFGFSVVEKKRAGKLNAQKLRDLGVPPGPAYGKLKNGISVVLDNGVTISPQDVLKKPMVGRKVCILGDCSGVVGDGGVKLCFEADLLIHEATLDDSQMDKAREHGHSTPQMAAAFAKLCRAKRLVLTHFSQRYKPTALAREGEADGIAELRKQAEAVLELQEVTLAEDFMVIGIPIKK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity).
What are the official names of this protein?
Zinc phosphodiesterase ELAC protein 1, ElaC homolog protein 1, Ribonuclease Z 1, RNase Z 1, tRNA 3 endonuclease 1, tRNase Z 1.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=Mainly cytosolic.
Protein: OBG_STAAS
Sequence: MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_SHEPC
Sequence: MFYKIAQKVMFQMDPERAHNLAIGSLKMTGNSPLNCFYRQTIAPAPVTFMGLTFPNPVGLAAGMDKDGESIDAFHAMGFGHIEVGTVTPRPQPGNDLPRLFRLKPAKGIINRMGFNNKGVDNLVRNLIAKKSDIMVGVNIGKNKDTPVEQGKDDYLICMDKVYPYAAYIAVNISSPNTPGLRSLQYGDLLDELLSAIKTKQLELAEKHKKYVPIALKIAPDLTIEEIENIADALIKNKFDGAIATNTTLTRDGVSGLANANESGGLSGKPLTELSTKVIRQLAACLKGQIPIIGVGGINSAEDALAKFDAGATMVQIYSGFIYQGPKLIKEIVEAYRLK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SUI1_METVA
Sequence: MPEICPICGLPKDLCVCEEIAKEEQKIKVYVTKRRFGKLMTVVDGFDADLIDVKDLAKKLKDICACGGTVKKDSIELQGDHRKKAEEILIKMGFSKDMIDVR
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.