PharMolix/UniProtQA huggingface dataset:
Protein: GRA3_GIBZE
Sequence: MPTPVESHSLLHSGLTLCGSIISVNQDRRKTSTLGCVIQVGSGFYGLTAAHAVRKSRAYPTLPLNSHTDEGLGAASDGPMTSHVLRNWQNPFMACKNAEAVELDDHSTSEVAVDESVEDVDFVTDVEYEDLREDDDNHGDDSTTSMPNDVFHEDYLTSAPQEGMMETQAMFLSIPELNDKCLVSRRARPNMAHRVTHGDSGSIVIDARTNVVYGHVVASNPLGEIYISPIGATLEQIQSHFPGSKVSLPDPLTILTGLATFGHETIGRKRARYPDKLRNLGLSPDTEYTRLVTPTANKSLDFSNYPKFHYFHQCSEDSSSNRRVNEVEKSQPANLTLDCNTVELGLRQSTWHQADSPVPLSSVKEESGLGKLARSPAEPAPSRPLPGSSIPVVISQSTGRELYSNGVTEATLSSKLSDEAEADTSIKPDSDAASPTDCRIIGHLRTRPVGLERDLSSTYNAALSMDQDPEELLQQDIFPMRVWRSLSTLKQRLPSQERLENLTWRMTHINLRKPKEQEEPKRHRTSNNSIVGSSDIADVGKTSKQKAIQPNIVELDVVTSPENIPLPASLVPISSSEATWQVDKKSVSSVTFGQSSGCFPPSYQGFRPDAPEKGNLPRATTTSYHLPPQPIGWPTCIPSNMKWHSLVNMSTLAADEHEGEGRADTNRHVSTQSNMPTEQSLLPQGDESVPPTCTNCFTLTCDILARNENVDQLAIDAPGHITSAKAVYNLYTFISYLLIF
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of gramillins A and B, bicyclic lipopeptides that induce cell death in maize leaves but not in wheat leaves (PubMed:30395461).  The nonribosomal peptide synthetase GRA1 incorporates respectively a glutamic adic (Glu), a leucine (Leu), a serine (Ser), a hydroxyglutamine (HOGln), a 2-amino decanoic acid, and 2 cysteins (CysB and CysA) (Probable).  The biosynthesis of 2-amino decanoic acid incorporated in gramillins could be initiated by a fatty acid synthase composed of the alpha and beta subunits FGSG_00036 and FGSG_11656 (Probable).  The cytochrome P450 monooxygenase FGSG_15680 could hydroxylate the fatty acid chain (Probable).  Subsequent oxidation to the ketone by the oxidoreductase FGSG_00048 and transamination by aminotransferase FGSG_00049 could form 2-amino-decanoic acid (Probable).  On the other hand, FGSG_15680 could also be responsible for the HO-modified glutamine at the gamma-position (Probable).  Whether hydroxylation occurs on the fully assembled product or on the Gln residue prior to assembly into the gramillins requires further proof (Probable).  The thioredoxin FGSG_00043 could also be required for the disulfide-bond formation between CysA and CysB (Probable).  The specific involvement of the remaining proteins from the cluster is more difficult to discern, but could have broader regulatory (FGSG_00040 and FGSG_11657) or enzymatic functions (FGSG_00044 and FGSG_00045) (Probable).  The final C-domain of GRA1 does not possess the expected sequence of a termination CT domain, often implicated in macrocyclization and release of a cyclopeptidein fungal NRPs; and the thioesterase FGSG_00047 may act in concert with the terminal C-domain of GRA1 to catalyze the formation of the macrocyclic anhydride and release of the products (Probable).
What are the official names of this protein?
Gramillins biosynthetic cluster protein FGSG_11657.
Protein: MUG4_SCHPO
Sequence: MTPPSSSSHFPSPSSANNDFHSLSLEAHGSLSDKFISQFRLNYTIIPIAQKSNISLPFLTLSPCSFTICSLRARLHSLHGPSTVFLKRETSQISARVNDENGFTASPSFFSVDCFDELFPTLSTTDEQPKEPSIISISSSSSDPSSSPPPSSSLLKTPDNDFCARPETFVKSDTADIKLQIHQNNLVLTFLDTTTVSKVNIVLEIHIPVLRDFVTFEQYIPLMFLPSPFETILSFDNLKSDSPSSDLHLGWDHTVSKESMSQSIAEVLNPYNKGVSRSLNDATNMETYHWSPFPPQFSTFNDNALRLRIYYKPKSWLPKNSSCSLSVDVKATLLETTPPSCEVSYNLLLTCRSSNRFRLFPASTPNSNGLCRNDSKCRFLMILPETIIKSPSSFIGDSYNIANIDPPSSMNVQSSEFRVGEVQSFTTNTSSFAFTFKEIVQLGSKASVPMILFPAPSNYKLTIEKPPFPCDLTIPHTAINDSWLPMKLKETNAISYYRKTCSSCKYPFQFFINKLPFYQSPSLPLSATYVWIASALLSVQPGNGSFNIMLSLKFVSSMKPGTELLTIKQPKSSLLNWGLVNGYPKTEGRIVLLPRNDIVLIQADQPTSVFDLCWTIKPTYEKSSNFSCLQLPIPVLNTPILTPVTINIQSTTYYLIGYANQNSKKTLDQPTSLLVLGCKAKNVSELILSYLPEKPIPDGAPIVTNVVETNKTNEAPSSFRKCLQQFLVFLTFTGMTLFILYQLTFPYGVAKDNSSFIDTPLPHSCEMEKSLNVLQHKVLQLQAVNMKLHDYYEKEPTEIYKTVSVTSTQIMPAVTKMSSFELEREQFHKAFGFLRLNRKKDDNAN
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 4 protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SEY1_TALMQ
Sequence: MVDQRPRAGSRSFTAPSLIGTNGHFASVGDAAHDPKAYEHGVQVIDEEKEFNPNLSKYLSLEDVTNAGFNYHLISVFGSQSTGKSTLLNHLFGTQFSVMSDKERRQTTKGIWMSKNKTKHEDPNARMADNILVMDVEGTDGRERGEDQDFERKSALFALATSEVLIVNIWEHQVGLYQGANMGLLKTVFEVNLQLFLKDKNTTHRSLLFFVIRDFMGNTPLKNLETTLLEDLSRIWASLSKPQGLERSTIHDYFDFAFYGLPHKGYKPDEFAAEAKKLGSRFREGRRDRKEQLMGASIENGVFLPEYHRRIPADGFAHYANGIWDQIVNNKDLDLPTQQELLAQFRCDEISREVIAAFDEAIAPFEEKQAAGVRAGELVILGGLGAAMRGARVKAVKNFETEASRYHKGVYQRKRAELEGKIDTRLKALFQGQLNAAHKSGVKDFSDAVSNAVKAGQKKGASYDFAEIVKQETKAALERYEKEARASLVEGTSWSNYKQELKLYQKDLAEVSGQLRRDEMRRLATRVERWVRSRLSDSVSLEFNSLGSGRGGSGAPETGEKPSESKIWDRIWNLFVETVLDAERRFTDRATSFDASVDEVDVGLWRLRRKSWGVLRLKVEEEMMEGNLLLKLRENFEDKFRYDEAGVPRIWRPTDDIEGIYTRARESTLTLIPLLSKFHLAENNAPPPLDRWVGHTPSSATAADEEDLTPIGGVDEEDGKSLEEEVTILNDAKRQDLTVRFKKAADGVYVEAKRSAIGGITQVPLYFYGLLLALGWNEIWAVLRNPAYFFLLFVCAIGAYVTYQLNLWGPILKMADAASRQALEELKKKLREFLEASDTGRQAMAMSSGEEYEMSSLNRGGKRVEDEDENDDI
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein sey1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: ALSE_ECOLI
Sequence: MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTLSPFFVSQVKKLATKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEIRRHDMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKLAELKAWREREGLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQILAAKSEVQPHAKTA
What is the function of this protein?
Catalyzes the reversible epimerization of D-allulose 6-phosphate to D-fructose 6-phosphate.  Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
What are the official names of this protein?
D-allulose-6-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family. AlsE subfamily.
Protein: YOJN_BACSU
Sequence: MNRKGNLSMTTQLQHLTLPEDIQQKLLSYKEQPISPEFQSLIGTSGYEAEDEAILFDAIIALAMGKNVLLKGPTGSGKTKLAETLSSYFHKPMHSVNCSVDLDAEALVGYKTIENQSGQATIEFVSGPVTKAMKEGHFLYIDEINMAKPETLPILNGVLDYRKMMTNPFTGEVIRAKSGFGVIAAINEGYVGTVPLNEALKNRFVIIDVPYIKGELLKQVLMSQSALKDEKLIDRFITLSSDLIVQANNGQVSEEAASIRALIDTCDLAAYIPPRRAIERGIVEKLDDDREKAAVRNIAETLFE
What are the official names of this protein?
Uncharacterized protein YojN.
What is the protein family that this protein belongs to?
Belongs to the CbbQ/NirQ/NorQ/GpvN family.
Protein: RIMP_CERS1
Sequence: MSDLVAKTAIDRRLADIVTPVIEGMGFELVRLRLMSGKTRTLQIMADRPDGGIVVDECAEISTAVSAALDVEDPIEENYTLEVSSPGIDRPLTRLKDFDVWTGYEARIETTELIDGRRRFKGELAGTEGDEVLITIEDGRDSYVTIGLKFDWLADAKLILTEELIAEMLRQKKASGNFDESQFDEIEESEGEEADEAEQPPTKH
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_RICRS
Sequence: MEIILIKPVRKLGKIGDILKVADGFGRNYLLPQKLAIRATEPNKELIVKQKHEFEAKDKQIREEVEKINALIKDQQLVFIRQTSNDGKLFGSVTNKEIANKLSENISYNISHSNVILDKQIKSTGIYTVEIRLHAELNAIVTVIVARSESEAQDYLREQKTETSEDLAESA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SAC1_RAT
Sequence: MAATAYEHLKLHITPEKFYVEACDDGADDVLIIDRVSTEVTLAVKKDVPPSAVTRPIYGIMGTIHLVAGNYLVVITKKMKVGEFFNHVIWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLSTDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYSGNRASFVQTRGSIPVFWSQRPNLKYKPDPQINKVANHMDGFQRHFDSQVIIYGKQVIINLVNHKGSEKPLEQTFAKMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGKVVTNQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLVMDGFNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDELDSHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID
What is the function of this protein?
Phosphoinositide phosphatase which catalyzes the hydrolysis of phosphatidylinositol 4-phosphate (PtdIns(4)P), phosphatidylinositol 3-phosphate (PtdIns(3)P) and has low activity towards phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:10887188, PubMed:27044890).  Shows a very robust PtdIns(4)P phosphatase activity when it binds PtdIns(4)P in a 'cis' configuration in the cellular environment, with much less activity seen when it binds PtdIns(4)P in 'trans' configuration (By similarity).  PtdIns(4)P phosphatase activity (when it binds PtdIns(4)P in 'trans' configuration) is enhanced in the presence of PLEKHA3 (By similarity).
What are the official names of this protein?
Phosphatidylinositol-3-phosphatase SAC1, Phosphatidylinositol-4-phosphate phosphatase, Suppressor of actin mutations 1-like protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Trafficking between the ER and Golgi is regulated by nutrient status and by TMEM39A (By similarity). Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS) in the presence of phosphatidylinositol-4,5-bisphosphate (PubMed:27044890).
Protein: ISPG_EHRRG
Sequence: MQCDFVDRILNEYDLLNAIVYRSKFTHEVKVGDVIIGGNNPIVVQSMALGGSGDVYQDAREVLELAQAGSELVRIAINSDKAIKSVPYIRDVLINHGFNSKMIIGCGQYEIARLVKQYPECALALGKIRINPGNIGFGDKRDKNFEDIIEFAIKNDIPIRIGVNWGSLDKYLAAKLMHDNSLRGTPDPDYVVLRKALVISAITSAKHAEKVGLPANKIVISCKVSKVRDLISVYTMLSKICDYPLHLGLTEAGSGVKGIVGSSAGISYLLLHGIGNTIRVSLTQQPGESRTNEVKLCQEILQSIGLRNFSVQVTSCPGCNRTNPKYFHQLVSDVNKYVADRMSVWKSANPGVENMTIAVMGCVVNGPGESKHANLGISMPGYGERSVAAVYQNGEKLCTLEGNNIFEQFVSIIENYVSIYYH
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GCSPA_NITEC
Sequence: MPFIPHTEEDVTEMLASIGATSIDELFDEIPAELKNGKLTQVPTGMSEMEISRLMYERAQKDGFYLSFIGAGAYEHHIPAAVWQITTRGEFYSSYTPYQAEASQGTLQLLYEYQTMMASLAGMDVSNASLYDGASALAEAALMAVRQHKSSRRILVPQTVHPIYRSVVRTIVRNQAIEVVEVPYDPATGQVSIDQLDQFAQEEFAALIIPQPNFFGVLEQVDTLADWAHDKQSLAIAVVNPTALAMLKPPGEWGRQGADIAVGEGQPLGIPLSSGGPYFGFMACKQELVRQMPGRIIGRTTDLEGKEGFALTLQAREQHIRRSKATSNICTNQGLMVTAATIYMSLLGPEGLYRVAAQSHANTLALVEQLETLPGVKKAFHSPFFHEAVLQLSVPADEVLNKLKAQGVLGGVLLENYYPDLKNTLLVCATETKIAEDLDKYTEMLRQILKA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: ACKA_STRPG
Sequence: MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEHIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKYIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT2A2_CHICK
Sequence: MENAHTKTVEEVLAYFGVNESTGLSLEQVKKLKEKWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKARDIVPGDIVEVAVGDKVPADIRITSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVIATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVEGDSCSLNEFTVTGSTYAPMGEVHKDDKLIKCSQYDGLVELATICALCNDSSLDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHVRVGNAKIPLSSGIKQKIMSVIREWGTGRDTLRCLALATHDNPPRKEEMNLEDSSNFINYETNLTFVGCVGMLDPPRIEVASSIKLCKQAGIRVIMITGDNKGTAVAICRRIGIFVEDEDVSTKAFTGREFDELSLAAQRDACHHARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFSGVDCVVFESPYPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWENIWLVGAICLSMSLHFLILYVEPLPIIFQITPLNVTQWLMVLKISLPVILLDETLKYVARNYLEPGKDSVQPATKPCSLSACTEGVSWPFVFITLPLVIWLYSTDTNFSDMFW
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen.  Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle.  May act as a regulator of TNFSF11-mediated Ca(2+) signaling during osteoclastogenesis.
What are the official names of this protein?
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MRAY_ACIAC
Sequence: MLLMLSQWLQGLSPEFGFFRVFQYLTFRAVMAAMTALLIGLLAGPKVIRMLTALKIGQPIRGYAMESHLSKSGTPTMGGVLILGAIAISTLLWFDLSNRFVWVVLAVTLGFGAIGWVDDWRKVVRKDPEGMRSREKYFWQSVIGIVAALYLVFCISENSNARVFELFVTWIQSGFSMDLPPQAGLLVPFFKEVSYPLGVLGFVILTYLVIVGSSNAVNLTDGLDGLAIMPVVMVGASLGVFAYVTGSAVYSKYLLFPYIAGAGELLIFCSAMAGAGLAFLWFNTHPAQVFMGDVGALALGGALGTIAIIVRQEIVLAIMGGIFVVEALSVMLQVTWFKYTKRRYGEGRRLLKMAPLHHHFEKSGWKETQVVVRFWIITMLLCLIGLTTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CX6A1_SHEEP
Sequence: SGGAHGEEGSARMXKALTYF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6A1, mitochondrial, Cytochrome c oxidase polypeptide VIa-liver.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: MNMG_SALPC
Sequence: MFYQDPFDVIIIGGGHAGTEAAMTAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVSRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRNNLDRSPMYAGVIEGIGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIHGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEMGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAESADEVNAHLTTPLSREASGEDLLRRPEMTYAQLTSLAAFAPALEDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_THEAC
Sequence: MNINDVKRAVSEIKEKSPQRKFEESVEIAVNLKDVDMSNPKNRINEEILLPNGRGKDVKIAVFGSDELKSKARGVADFVFGAEDISKFAEDKKAFKKIVNQAYFFIAEATLMANIGKSLGQVLGPRGKMPRPIPPGQDPAPLIKNLKNTVKARSRNALTFHVPVGTRSMDADKISENIMTVINRITGKLERGASNIRSIYVKTTMGNAVEIKAGDEK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: GDAP2_DROPS
Sequence: MRLDTNSNVDFKAFESSSSSSSCLVKLDNLATWGGSQKTDTRLPITDYSTLGGPRHNRSPFPLSKDVNNRLVIWDGDMTTLDVDAITNTSDETLTESNIISERILAVAGNQLREELSTNVKECRTGDVRITRGYNLPAKYVLHTVAPTYREKFKTAAENTLHCCYRNVLCKAKELNLHTIALCNISVHQKSFPADVAAHIALRTIRRYLDKCTLQVVILCVNSNERGTYEVLAPLYFPRDQLEERSALWQLPKDIGGEFGEPQHPDPDRQIRIIRNPQHSVHMRHGHTDDDSDVSPHDMEGNSSDLEYGAKDMNGLSPNSYSSGLQTQLQRDLDRQHLLSDRPRAGVYENVISEGVEGIEHQERYERLLRRAQVEDLTEVSGIGCLYQSGVDRLGRPVIVFCGKWFPAQNIDLEKALLYLIKLLDPIVKGDYVISYFHTLTSTNNYPSLHWLREVYSVLPYKYKKNLKAFYIVHPTFWTKMMTWWFTTFMAPAIKAKVHSLPGVEHLYSAITKDQLEIPAYITEYDMATNGLHYFNPVPTAS
What are the official names of this protein?
Protein GDAP2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GDAP2 family.
Protein: CAPSD_TPCTV
Sequence: MPYKRKLTSYFPQSKRFRGAKSGMAVVKTSASRRLYKKGKRKPDRIKTYTYAFSSICTDKGTIVYMNSWSLGLGPQQRSSDIEILKSMYIRLTVALSENAASQVKTYVVKWALIVDQVPGETLVGVADVYKTCPSPYPYVQCAYIADDNHSRFQVLRSGFLSLSGNGLAVGSSTRTGCPAMKNMASINKFCKNLNVRCVYDADSATGDIASIKRGAVYLVIWPDVEIRYGFSCTMYHRNGNA
What is the function of this protein?
Encapsidates the viral genome into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  Plays a role in protection of the genome from degradation, virus acquisition and transmission by insect vectors, infectivity, and systemic movement.  The CP of monopartite geminiviruses is absolutely essential for virus movement (By similarity).
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell- to-cell movement and spread (By similarity).
Protein: TPS1_TOOSI
Sequence: MASHVLASLRSASARISTRLQSRSCILATATSFSNGFVSASLVQSMSTTTQCDESVARRSANYEPPIWTYDYVQSLRNPYAGGSYAKRIEKLKGDVRVMLQKLVDLDPLHQLEFIDTLQRLGVSYHYQEGIKGILDTVYNNYMQKQESLYAVALGFRLFRQHGYHIPADIFSSFRDDKGNLKSCLGDDCRGILALYEAAHLLVEEERDIFYEIVNFTTAYLKEYVKHDNDEYLSALVNHSLEIPLHWRVLRLEARWFIGAYERAPNTHPILLEFAKLDFNDVQATHQEDLKFMSRWWKNTGLDREKMNFARDRIVQNVLWSLGIIFEPQFAYCRRMSVKAYAFITLIDDVYDVYGTLDELELFTDAVDRWDATAIEKLPDYMKPIFRTLYTSINDMALDARKDRGVDTRPFLHKAWSTLFNYYLMEAKWFSNGYMPTYKEYMDIAWFSVGGPVMIVHSYCAIANPATKENMEFFQEYYDIIRLWSTILRFKDDMGTSSDELKRGDNPKSIQCYMHESGVSEKEARQHLGNLITETWMKVNKNRAENPHLSDVYMGIAINMARMALCMYQFGDGHAVEAHSKDRVLSLLINPIPCP
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds known for their medicinal efficacy for treating enteritis, dysentery, itch and some cancers (PubMed:23072391).  Mediates the conversion of (2E)-geranyl diphosphate (GPP) into (4R)-limonene (PubMed:23072391).  Can only use GPP as substrate, no activity with farnesyl diphosphate (FPP) (PubMed:23072391).
What are the official names of this protein?
Sesquiterpene synthase 1, TsTPS1, (4R)-limonene synthase TPS1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LEC_LENCU
Sequence: MASLQTQMISFYLIFLSILLTTIFFFKVNSTETTSFSITKFSPDQKNLIFQGDGYTTKGKLTLTKAVKSTVGRALYSTPIHIWDRDTGNVANFVTSFTFVIDAPSSYNVADEFTFFIAPVDTKPQTGGGYLGVFNSKEYDKTSQTVAVEFDTFYNAAWDPSNKERHIGIDVNSIKSVNTKSWNLQNGERANVVIAFNAATNVLTVTLTYPNSLEEENVTSYTLNEVVPLKDVVPEWVRIGFSATTGAEFAAHEVHSWSFHSELGGTSSSKQAADA
What is the function of this protein?
D-mannose specific lectin.
What are the official names of this protein?
Lectin.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: IF1_PSEPF
Sequence: MSKEDSFEMEGTVVDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVRVELTPYDLSKGRITYRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_SYNR3
Sequence: MAKNKGVRIVVTLECTECRSNTDKRSQGVSRYTTEKNRRNTTERLEIKKFCPHDNKMTVHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.