PharMolix/UniProtQA huggingface dataset:
Protein: ABC3A_HUMAN
Sequence: MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
What is the function of this protein?
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons.  Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons.  Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA.  Can induce somatic hypermutation in the nuclear and mitochondrial DNA.  May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
What are the official names of this protein?
DNA dC->dU-editing enzyme APOBEC-3A, A3A, Phorbolin-1.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MNMA2_PHOV8
Sequence: MRETESNNKVLLGMSGGTDSSVAALLLQDAGYEVTGITFRFYEKENDTEYLEDARALCERLNIPHLTYDVRDTFRKTIIDYFINEYMAGHTPVPCTLCNNYLKWPLLKKISDEMGIYHFATGHYVRRRFINGCYHITTGVDPDKDQSFFLWGLPQEILQRMLLPMGNLTKARVREIAAERGFLKAAHKRDSLGVCFCPMDYRTFLHKELPEGSILPGKFFDEMGNFIARHKGYPFYTIGQRRGLGIDLNRAVFVKEIIPAENKVILSDLKALEKTEMRLKEWHITNPALLLNKDDIIVKIRYRKQANRCTVTLQPDNTLHVQLHEPLTAIAPGQAAAFYRDDVVLGGGIII
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 2.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_CYACA
Sequence: MSGINPNKQPVELNRTSLFWGLLLIFVLAVLFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GLMM_BACLD
Sequence: MGKYFGTDGVRGVANSELTPELAFKVGRFGGYVLTKDKERPKVLIGRDTRISGHMLEGALVAGLLSIGAEVMRLGVISTPGVAYLTKAMDAEAGVMISASHNPVQDNGIKFFGGDGFKLSDEQELEIERLMDQPEDHLPRPVGADLGMVNDYFEGGQKYLQFLKQSADEDFTGIHVALDCAHGATSSLATHLFADLDADVSTMGTSPNGLNINDGVGSTHPEALAEFVKEKGADVGMAFDGDGDRLIAVDEKGNIVDGDQIMYICAKYLKSEGRLTDNTVVSTVMSNLGFYKALEAEGIKSVQTAVGDRYVVEAMKKGGFTLGGEQSGHLIFLDYNTTGDGLLSAIMLMNTIKMTGKPLSELAAEMQKFPQLLLNVKVTDKHKVTENEKVKAVIEEVEKEMNGDGRILVRPSGTEPLVRVMAEAKTKELCEKYVGRIADVVKAEMGAE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: VE7_HPV18
Sequence: MHGPKATLQDIVLHLEPQNEIPVDLLCHEQLSDSEEENDEIDGVNHQHLPARRAEPQRHTMLCMCCKCEARIKLVVESSADDLRAFQQLFLNTLSFVCPWCASQQ
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta) (PubMed:26405230).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: NRDC_MOUSE
Sequence: MLRRVAVAAVCVTGRKLRCEAGRELTALGRIEARGLCEESSKPFPTLTMPGRNKAKSTCSCPDLQPNGQDLGESGRLARLGADESEEEGRSFSNVGDPEIIKSPSDPKQYRYIKLQNGLQALLISDLSNVEGKTGNATDEEEEEEEEEEEEDDDDDDDDDDDDEDSGAEIQDDDEEGFDDEEEFDDDDDDEHDDDDLENEENELEELEERVEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPKKNNIDTHARLREFWMRYYSAHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPKPNFSHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSYLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAHTVFQYLKMLQKLGPEKRVFEEIQKIEDNEFHYQEQTDPVEYVENMCENMQLYPRQDFLTGDQLLFEYKPEVIAEALNQLVPQKANLVLLSGANEGRCDLKEKWFGTQYSIEDIENSWTELWKSNFDLNPDLHLPAENKYIATDFTLKAFDCPETEYPAKIVNTAQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLTEFSSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYSRWSMIDKYQALMDGLSLDSLLNFVKDFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFAPLEREMPVQFQVVELPSGHHLCKVRALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSETVDKKIEEFLSSFEEKIENLTEDAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVSWFKAHRGPGSKMLSVHVVGYGKYELEEDGAPFGEDSNSREGMQLTYLPPSPVLAESTTPITDIRAFTATLSLFPYHKIVK
What is the function of this protein?
Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.  Is a critical activator of BACE1- and ADAM17-mediated pro-neuregulin ectodomain shedding, involved in the positive regulation of axonal maturation and myelination (PubMed:19935654).  Required for proper functioning of 2-oxoglutarate dehydrogenase (OGDH) (PubMed:28017472).
What are the official names of this protein?
Nardilysin, N-arginine dibasic convertase, NRD convertase, NRD-C, Nardilysin convertase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
Protein: PPAX_BACC2
Sequence: MRINTVLFDLDGTLINTNELIISSFLHTLNTYYPNQYKREDVLPFIGPSLHDTFSKIDESKVEEMITSYREFNHDHHDELVEEYETVYETVRELKKQGYKVGIVTTKARQTVEMGLQLSKLDEFFDVVVTIDDVEHVKPHPEPLQKALELLDAKPEEALMVGDNHHDIVGGQNAGTKTAAVSWTLKGRAYLEAYKPDFMLDKMSDLLPILSNMNRS
What is the function of this protein?
Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P.  Might play a role in controlling the intracellular pyrophosphate pool.
What are the official names of this protein?
Pyrophosphatase PpaX.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PpaX family.
Protein: KLRF1_MACFA
Sequence: MQDEERYMTLNVQSKKRTSTQTTQLTFKDYSVVLHWYKILLGISGTLNGILALALISLILLVSQGVLLKCQKGSHSNTTEHEDIGDLKMNNGTRRNTSNKDLCVSRSADQTVLCQSEWLKYRGKCYWFSNEMKSWSDSYVYCLERKSHLLIIQDELEMAFIQKNLRQSNYVWMGLNFTSLKMTWTWVDGSPLDPKIFFIKGPAKENSCAAIKESKIYSETCSSVFKWICQY
What is the function of this protein?
Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.
What are the official names of this protein?
Killer cell lectin-like receptor subfamily F member 1, Lectin-like receptor F1, Activating coreceptor NKp80.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: QCRB_BACSU
Sequence: MLNKIYDWVDERLDITPMWRDIADHEVPEHVNPAHHFSAFVYCFGGLTFFVTVIQVLSGMFLTMYYVPDIKNAWESVYYLQNEVAFGQIVRGMHHWGASLVIVMMFLHTLRVFFQGAYKKPRELNWIVGVLIFFVMLGLGFTGYLLPWDMKALFATKVGLQIAEATPLIGTQVKTLLAGHPDIVGAQTLTRFFAIHVFFLPAALFGLMAAHFIMIRKQGISGPL
What is the function of this protein?
Component of the menaquinol-cytochrome c reductase complex.
What are the official names of this protein?
Menaquinol-cytochrome c reductase cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ODP2_RICPR
Sequence: MPIKILMPALSPTMREGNLARWLKKEGDKVNPGEVIAEIETDKATMEVESVDEGILAKIIIPQNSQNVPVNSLIAVLSEEGEDKADIDSFIAQNNSVSLSLKTDATLKKSNDSITNVEGIKHDSNKIFASPLAKRLAKIGDIRLENVQGSGPHGRIVKQDILSYDSSTSSNKIVYRDTEEYRSVPNNNIRKIIAKRLLESKQTVPHFYLSIECNVDKLLDVREDINKSFSEDKVTKISVNDFIILAVAKALQEVPNANASWSEDAIRYYNNVDISVAVAIENGIVTPIVKDANKKNIIELSREMKTLIKKAKDNKLTPIEFQGGGFTISNLGMYGIKNFNAIINTPQSCIMGVGASTKRAIVKNDQIIIATIMDVTLSADHRVIDGAVSAEFLASFKRFIENPVLMLI
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: RL5_TREDE
Sequence: MSNYVPRLKKVYTEQIMPELKKEFNYSSVMQIPRLKKVVVSMGVGVALTNRKLLDAAVTDLETITGQKAVKTKARKSIANFKLREGNEIGAMVTLRGARMYEFLDRFINVALPRVKDFRGVNPNGFDGRGNYSVGITEQIIFPEIDFDKIERISGLNVNVVTSAETDQEARSLLAKFGMPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PCD15_CHICK
Sequence: MLQQFCLWKWLAVGIAVATILASSLAQNDEDCKLARTGPPATIVPIDEESRNGTILVDNMLIKGTAAGPDPTIELSLKDNVDYWVILDPISQRLYLNSTGRVLDRDPPMSIQSIVVQVQCVNKKVGTIINHEVRIVVRDRNDNSPQFQQQRYYVAVNELTPVGTTIFTGFSGNNGATDIDDGPNGQIEYVIQYNPNDKTSNRTFDIPLTLSGAVVLRERLNYEEKTRYFVIVQANDRAQNLHERRTSTTTLTVDVLDGDDLGPMFLPCVLVNNTRDCRPLTYQASLPELTDPVHVNPISVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPQYFHMNLTTAELTLLKPINRDLHQKFDLVIKAEQDNGHPLPAFANLHIEVLDENNQKPYFTKSTYEGFILESSPVGTTISDSRNLTSPLQITVLDNDVEETKDPQLHLFLNDYNTFFTVTQSGITRYLTLLQPVDREAQQLYTFSMIASDGVQESTPVTVNIVVIDANDNSPTFSNISYNVKIYTDMGPGEGVIKLTAVDADEGPNGQIVYEILAGDQGDFIINDRTGLIAIAPGVVLSVGRSYALTVKASDSAPPAQRRSSITTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRTGAILLNLQAFDREGDPIRYLIENGDPQQVFNLSQSSGLLALGKPLDRESTDRYILIVTASDGRPDGTSTATVNIVVTDVNDNGPVFDMFLPKNLSVQEEEANAFVGQVRATDPDAGVNGQVHYSLANFKNLFRITSNGSIYTAVKLNREVRDYYELIVEATDGAVDPRRSTLTLAIKVLDIDDNSPVFTNASYSVLVPENLPPGTVFLQIEAKDVDLGSNVTYRIRTQEALEYFALNKYTGELSLLKSLDYESFSDTDATFTFLVEAFDSKGTMPPGLATVTVRVKDMNDYSPVFSKTLYRGMVAPDAVKGTVITTVSAEDQDPPGTPASRVRYKVDVVQFPYSASIFDVEENSGRVVTRVNLNEEPSTVFKLVVIAYDDGDPVKFNTTTVEIAVLQPSVIPRFTQDEYRPPPVSESAPKGTVVTVVMAAALNQTIVYSIVSGNEEDVFAINNRTGVISVKKPLDYERVTSYELRVQADSLQVVRSNLRVPSKSNTAKVFIEVKDENDHAPVFTKKMYIGGVSEDAKMFSSVLKVKADDKDTGNYSAMQYRLIIPPIKDGKEGFVIEAYTGLIKTAMLFKNMRRSYFKFQVIATDDYGKGLSSKADVLVSVVNQLDMQVIVSNVPPTLVEQNKDQLIGILERYVQDQIPGATVVVESIGARRFGDGYSEEDYTKSDLMVYAIDPQTNRAIMRNELFKFLDGKLLDINKEFQPYLGQGGRILEIRTPDVVANVKKQAQAVGYTEGALLALAVIIILCCMPAILIVMVSYRQRQAECAKTARIQMALPAGKPASTAANNLYEELGDSTILFLLYHFQQSRGKKSVLEEGDRQRVISSFASRAIEAHKQSNINGSLNNNLPKSSSNITFLSDENPLTTQNPLYVEGVTQSPAAAGLLRKRSDALDTLSPMQLVLRDASLGGSHRAWTVPAHVTKRHAPGSLSRPVIMDPVQWQQERLKAENEGTENQHSRVDISSPLFQKISGPTLTVKEKARQFEQQALQEMKQVKSPDVKSTRSPTHSICLQERDNTLEQSPKSVFASPCLRSSPLSSPTPCEVVEPEPSAVPSVIITHHDYPEELSPPPTRKPTPPSFRIKKPVCQSFLAPQTKGEVTENIPDPPKTPPPPPPLLPPPPPSPPLLPPHPPTLPLASVPSSSSLPSTQHLSPAKHSKSPAKQPAVPPPAAVPEPPPRRELKGILKNIQNLAAIEKSVANMYSQIDKNHVLPKHISKLKPVATPELPTPEAAAEHNQQNGNLSCVVEELEKRFPSQSTAL
What is the function of this protein?
Calcium-dependent cell-adhesion protein.  Required for inner ear neuroepithelial cell elaboration and cochlear function.  Probably involved in the maintenance of normal retinal function (By similarity).
What are the official names of this protein?
Protocadherin-15.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: FBRL_DICDI
Sequence: MEGRGGSRGGAMARGGGRGGFGGGRGGFGGGDRGGRGGGRGGFGGGDRGGRGGFGGGRGGRGGFGGGDRGGRGGARGGRGGARGGKPAAGGKPGAKVIVEKHPRHEGVFIVRGKEESLATLNSVPGESVYGEKRVSVGEGEDKKEYRIWNPFRSKIAAGLHRGVDEIHIKPGSKVLYIGAASGTTISHVSDIVGPTGVVYGIELSHRPGRDLIGMAKKRTNVIPIIEDARHPQKYRMLIGMVDVVFADVAQPNQAQIVAQNSAYFLKNEGHFIISIKASCIDSTAPTEVVVQNEITKLKKEKLRPQHLLKTLDPYERNHSLVIGVYRKFGSSEK
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins.  Involved in pre-rRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.  Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
rRNA 2'-O-methyltransferase fibrillarin, Histone-glutamine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Fibrillar region of the nucleolus.
Protein: PUR5_RHIL3
Sequence: MSQSGKNGLTYSDAGVDIDAGNLLVEKIKPAVRSTRRPGADGEIGGFGGLFDLKAAGFTDPVLVAANDGVGTKLKIAIDADYHDTVGIDLVAMCVNDLVVQGAEPLFFLDYFATGKLDPDQGAAIVGGIAAGCREAGCALIGGETAEMPGMYSSGDYDLAGFAVGAAERGKLLPSGDIAEGDVILGLASSGVHSNGFSLVRKIVELSGLDWDSPAPFTEDKKLGEALLEPTRIYVKPLLKAIRETGAIKALAHITGGGFPENIPRVLPKHLAAEIDLATVKVPPVFSWLAKTGGVEAKEMLRTFNCGVGMIAVVAGENVATVSAALEAEGETVITLGRMIAREEGAAGTVYKGTLAI
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE2_COXBN
Sequence: MKHIRTRFAPSPTGYLHIGGVRTALFSWLFARQNNGAFILRIEDTDVARSTQASVDAILEGLRWLQIDWNEGPYYQSQRMDRYREVIEQLVKSDDAYRCYCSKERLIELRNTQLKNKQKPRYDGFCRDKAPRQSNEPFVIRFRNPVEGAVVFDDLIRGTISIDNRELDDLIIARSDGGPTYNLTVVVDDWDMKITHVIRGDDHINNTPRQINILHALGAELPHYGHVPMILGPDGKRLSKRHGAVSVLQYRDEGYLPEALMNYLIRLGWAHGDQEIFSREEMVQLFDISAVSRSPAAFNPEKLLWLNQHYLKTVSPTIIAEAFATQLEKAGTDLRNGPSLEQVIALQAERTKTLKEMAQRSLYFYQEVRSYDEKAARKHLLATIVEPLQRVRERLASLPSWEKEAIHEVIVETAQLHQLKLGQLAQPIRVALTGDTVSPPIDATLYLIGRDSALKRLDHAIRFIHQGMG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPH_LIGS1
Sequence: MAKLDAHDIIRTIAESKKKTPVKVYVKGDLNSLDVPSNVETYFTDNVGVMFGDWADVEPILKDSSVESYHLENDGRNTGVAMVDKKKFNARIEPGAIIRDQVEIGDNAVVMMGAVINIGAEIGEGSMIDMGAVLGGRAIVGKNCHIGAGTVLAGVVEPPSAQPVVIEDDVLIGANAVVLEGVRVGKGAVVGAGAVVTKDVEPYTVVMGMPAKKVKDVSQVDDSKTEIVDDLRKL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: HIS6_LISMF
Sequence: MLTKRIIPCLDVTAGRVVKGVNFVSLTDVGDPVEIAKAYNEAGADELVFLDITATVELRQTMIDVVERTAEQVFIPLTVGGGISSVSDMKELLQAGADKISLNSAAIKRPELIQEGAAKFGNQCIVVAIDAKWNGTNWSVFTRGGRNDTGLDAIEWAKKAVQLGAGEILLTSMDGDGTKNGYDIPLTKAISAAVSVPVIASGGCGNAAHMAEVFEKTKATAALAASIFHYGELSIKNVKTTLLEKGVNIRP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_ONYPE
Sequence: MKRGKKYLASLQMFDVKKTYPLQEAISLAKQTQVAKFDAAVECAFHLNLDPKKVDQNLRGALVLPHGTGKVLKVAVLAKGEQAKQAQEAQADYVGDQDLIDKIAKNWFDFDVLVATPEMMPQLSKLGRLLGPKGLMPNPKTGTVTNDVLQAVKEIKNGKIEYRLDKSGNIHAILGKVSFDETKLLENLKTLYLQLMAVKPRTVKGTYIKSVTISTTMAPGIKIDPVTISQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CLD23_HUMAN
Sequence: MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQDEPNFVLAGLSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALSFAPWCDERCRRRRKGPSAGPRRSSVSTIQVEWPEPDLAPAIKYYSDGQHRPPPAQHRKPKPKPKVGFPMPRPRPKAYTNSVDVLDGEGWESQDAPSCSTHPCDSSLPCDSDL
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-23.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: RPOA_PSE14
Sequence: MQISVNEFLTPRHIDVQVVSPTRAKITLEPLERGFGHTLGNALRRILLSSMPGCAVVEAEIDGVLHEYSAIEGVQEDVIEILLNLKGLAIKLHGRDEVTLTLSKKGSGVVTAADIQLDHDVEIVNPDHVIANLASNGVLNMKLTVARGRGYEPADSRQSDEDESRSIGRLQLDSSFSPVRRIAYVVENARVEQRTNLDKLVIDLETNGTLDPEEAIRRAATILQQQLAAFVDLKGDSEPVVIEQEDEIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLDNWPPASLKKDDKATA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RSMA_SYNSC
Sequence: MGFSGHHARKRFGQHWLLDESVLQRIIEAADLQSTDRVLEVGPGRGALTERLLAAGLKAVHAIELDRDLVQGLRDRFVVQPGFSLHQGDVLEAPLELSDGRIADKVVANIPYNITGPLLERLVGRLDRPVDPPYQRLVLLVQKEVAERIRARPGHSSFSALSVRMQLLARCHSVCPVPPRCFQPPPKVQSEVICLEPLPASERVMPDLAARVESLLKQAFLARRKMLRNTLAGVAEPNRLKDLAASAGFSLQQRPQELAPATWVALARGLNRGD
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPH_BACC1
Sequence: MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPETVQAFVNKKSGVLFGEWSEIKTILDENSKYIVDYVVENDRRNSAIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSAKPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTKAKTEIKQELRQLNPEK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: YQGF_CUPTR
Sequence: MPDAVGRELPRDGTVLAFDYGEKKIGVALGNFITREARALTILPNITVEGRFEAVAALIQAWNPVQLIVGMPVNPEGGEQPSMKLARRFGNQLNGRFGLPVEWVDERYTSRAASMAGARRGELDAEAARIILQQYFDQFPL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.