PharMolix/UniProtQA huggingface dataset:
Protein: SBH2_ARATH
Sequence: MMSFVISDEFLGTFVPILVYWVYSGMYICLGSLDKYRLHSKIDEDEKNLVSKSAVVKGVLLQQTLQAIISVILFKITGSDADAATTQQFSILLLARQFIIAMLVIDTWQYFIHRYMHLNKFLYKHIHSQHHRLIVPYSYGALYNHPLEGLLLDTIGGALSFLFSGMSPRTAIFFFSFATIKTVDDHCGLWLPGNPFHIFFSNNSAYHDVHHQLYGTKYNFSQPFFVMWDRILGTYLPYSLEKRANGGFETRPIKVSKDE
What is the function of this protein?
Involved in sphingolipid trihydroxy long-chain base (4-hydroxysphinganine) biosynthesis.  Can use C18- and C20-sphinganine as substrates to produce C18- and C20-phytosphinganines (D-ribo-2-amino-1,3,4-trihydroxyoctadecane and -eicosane).
What are the official names of this protein?
Sphinganine C4-monooxygenase 2, Sphingoid C4-hydroxylase 2, Sphingoid base hydroxylase 2.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RDGC_ECOSM
Sequence: MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLSMENPIELTLTEWVRSGSTAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YCEK_ECO57
Sequence: MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDSAWRYVTILDLPFSLVFDTLLLPIDIHHGPYE
What are the official names of this protein?
Uncharacterized protein YceK.
What is the protein family that this protein belongs to?
To E.coli YidQ.
Protein: LYSE_MYCTO
Sequence: MNSPLVVGFLACFTLIAAIGAQNAFVLRQGIQREHVLPVVALCTVSDIVLIAAGIAGFGALIGAHPRALNVVKFGGAAFLIGYGLLAARRAWRPVALIPSGATPVRLAEVLVTCAAFTFLNPHVYLDTVVLLGALANEHSDQRWLFGLGAVTASAVWFATLGFGAGRLRGLFTNPGSWRILDGLIAVMMVALGISLTVT
What is the function of this protein?
Catalyzes the efflux of L-lysine.
What are the official names of this protein?
Lysine exporter LysE.
What is the protein family that this protein belongs to?
Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEM6_SHEB2
Sequence: MSVPDAAVVKAFLLDLQNRICAGLQALDGQARFAADSWTRAEGGGGTSRVLTQGAVFEQAGVNFSHVTGAAMPASATAHRPELAGRSFEAMGVSLVIHPNNPYIPTTHANVRFFIAQKEGADPVWWFGGGFDLTPYYPFEEDVREWHQTSKDICAPFGDEVYPKYKKWCDEYFFLPHRNETRGVGGLFFDDLNQEGFDQSFSFMQAVGNGFLTAYAPIVERRKDTEFGERERQFQLYRRGRYVEFNLVYDRGTLFGLQTGGRTESILMSMPPLVRWQYAYTPEAGSPEADLYDNYLKPRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_BACAA
Sequence: MGVERIKAAFENGKKAFIPYVMGGDGGLEILKERIRFLDEAGASIVEIGIPFSDPVADGPTIQRAGKRALDSGVTVKGIFQALIEVRKEVQIPFVLMTYLNPVLAFGKERFIENCMEAGVDGIIVPDLPYEEQDIIAPLLREANIALIPLVTVTSPIERIKKITSESEGFVYAVTVAGVTGVRQNFKDEIHSYLEKVKSHTHLPVVAGFGISTKEHVEEMVTICDGVVVGSKVIELLENEKREEICEFIQATKQKEEA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: Y033_CALS4
Sequence: MKKHIFEDIILQNALNFTREMMNVFEDLLKNGMNITELVARIKELTDKLGREAIEAIIEELDRIIKEDKRRKEKWVVERKDKKRLTTVLGDIEYERTYYKSREDGRYTYLVDDALEIGRHERIEKGVKIKLVENAIEESYEKSSEKACPEKISKQTVLNAIREIGEVEVKREIKEKKEVRVLYIEADEDHVPLQDGSSETPRLIYIHEGREEKNGRNVLKNVYYKAYVGEKAEDIWIDVANYIEENYKEEKIEKIYIAGDGAPWIKEGLEWIVKSRFVLDRYHLNKYVLKATSKEPKYRDKIWRAINEGDKEGVKKIFGELIKIAKEEKEKEKIKEAKRYILNNWEGIKIYSEDEDVIGCSAEGHISHVFSARLSRNPLGWSREGLKLMAKLRVFSKNGGDLREVEWGKKKNINAGSYKLTEKQIKEAVRRVKTSTNEKINNITVLNIGKVTPIYRVLRALKYAQVI
What are the official names of this protein?
UPF0236 protein TTE0033/TTE0744/TTE0838/TTE0852/TTE1082/TTE1247/TTE1519/TTE1678/TTE1739/TTE1823/TTE2212.
What is the protein family that this protein belongs to?
Belongs to the UPF0236 family.
Protein: HEM1_SULIN
Sequence: MTSNEELLQNYCSILFTYKTIGISNLHLYYFRETEIKSLRQLINAEFAILQTCNRVEIYLYSNTNTISEINKMIQYLNNVHNEPIGNQARVICGKDSIKHLFLVASGADSLSIGEYEILSQIRSTIDMFKKLGFSGKYLQILFERAIKVGRKVREETSISKGKVGIYSLAIDEAKRQFNNFYDRKIVIVGAGEMGQKIANMLYNEGVKNVTIMNRTVEKAKQLALKFGYNYEKLDLDKLGSFDIAFISISHENLRLENKWNTLIVDITVPPLFTGNNVITLEELEKISKLNFKAREEELVKINKLVEDGIDELIYDYKKEIYSEFMSKIMKRVETIRENEIVRAYKELEKLGINNQQVKEILDLMTRSIIKKSFQPLFDNVRSLVFDGENSINYINFLIDIFKDGNIPIFETKKIKKKQISKRSSS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RS4_CYAP4
Sequence: MARYRGPRLRVIRRLGDLPGLTRKAVPSRRAYPPGQHGQARKKRSEYAMRLEEKQKLRFNYGLTERQLVRYVRRARRVSGSTGLALLQLLEMRLDNIIFRLGMAPTIPAARQLVNHGHVTVNGRVVSIPSYQCRPGNEIGIRNKENSRRLAEENLKFPGLANLPTHLELDKNKLMAKVNSVVEREWVALQVNELLVVEYYSRKV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ASL1B_DANRE
Sequence: MEATVVATTQLTQDSFYQPFSESLEKQDRECKVLKRQRSSSPELLRCKRRLTFNGLGYTIPQQQPMAVARRNERERNRVKQVNMGFQTLRQHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAVLQCGVPSPSVSNAYSAGPESPHSAYSSDEGSYEHLSSEEQELLDFTTWFDRYESGASMATKDWC
What is the function of this protein?
Transcriptional regulator.  May mediate transcription activation by binding to the E box-containing promoter (By similarity).  Involved in neurogenesis.  Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression.  May mediate transcription activation by binding to the E box-containing promoter.
What are the official names of this protein?
Achaete-scute homolog 1b, Zash-1b.
What are the subcellular locations of this protein?
Nucleus.
Protein: STI_ARATH
Sequence: MSGSRVSDLSKLHLKKELTQIRKAGRVLRDPGTTSSWKSPLDSSRSVALLETPASRNGGSSSQFPIRGESSTNRRGKEKKVFLYNWKTQKSSSEKSGLAKNGKEEEEEEEDASSWTQASVNDDDDVSDARNGGDSYRREIQSASMGFRCRDTNLASQGVSKMRKSNVGSCKKKSKKKISSSRLDCLSKYQPRDDIVARNCNAGSDDTEEELSNSEDLRKVTGASPLLLKLKQKNWSRSSSRLLRANNRKEDSSCTYNSTPALSTSSYNMYAVRNPSTVGSWDGTTTSVNDGDDELDDNLDLPGRQGCGIPCYWTKKAMKHRGGCRSCCSPSFSDTLRRTGSSILCGSQSVYRRHNRHSSGGYSKQKIACRSAQGVLPLLSYGGDGRGGSSLGTGLSDDELSTNYGELDLEAQSRLDGRRWSTSYRSQDGLEAVALDGEEEEGSTPETIRSFSQKYRPMFFEELIGQSIVVQSLMNAVKRSRIAPVYLFQGPRGTGKTSTARIFSAALNCVATEEMKPCGYCKECNDFMSGKSKDFWELDGANKKGADKVRYLLKNLPTILPRNSSMYKVFVIDECHLLPSKTWLSFLKFLENPLQKVVFIFITTDLENVPRTIQSRCQKFLFDKLKDSDIVVRLKKIASDENLDVDLHALDLIAMNADGSLRDAETMLEQLSLLGKRITTALVNELVGVVSDEKLLELLELALSSDTAETVKRARELLDLGADPIVLMSQLASLIMDIIAGTYKVVDEKYSNAFFDGRNLTEADMEGLKHALKLLSEAEKQLRVSNDRSTWFTATLLQLGSMPSPGTTHTGSSRRQSSRATDDDPASVSREVMAYKQRIGGLHFSKSASPASVIKRNGNHSHEAKPFSRVIDNNCYKSSSSSQMIESEGSIASHENSIASTMMLNQRSSEKLNDIWRKCIERCHSKTLRQLLYTHGKLISISEVEGILVAYIAFGENDIKLRAERFLSSITNSIEMVLRRSVEVRIILLPETELLVVPHQTRKPEMTNKSGHLNNIAGLNAETDVEVGSSVESRSKLPMQRIESIIREQRLETAWLQTADKDTPGSIIRVKPERNQILPQEDTYRQTNVASAISSSGLTTHQWVDELNNEVKLLKIGDNGELQENLTGTRGQHCPLSPSLLHDTNFGNNKDNLGGYESGSGRVGCNILFCWNTKKTQRRSKSKQVKGTPVRSRRNRKSRFSLFNGCAKPRKAEGNIRR
What is the function of this protein?
Acts as a key regulator of trichome branching through an endoreduplication-independent pathway.
What are the official names of this protein?
Protein STICHEL.
What is the protein family that this protein belongs to?
Belongs to the DnaX/STICHEL family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRH_NOSS1
Sequence: MGTNYRRVLLKLSGEALMGNMGYGIDPEVVKEIAQEIAEVIATGVQIAIVVGGGNIFRGVKAASAGMDRATADYIGMIATVMNAMTLQDSLERIGVQTRVQTAIAMQELAEPYIRRRAIRHLEKGRVVIFGAGSGNPFFTTDTTAALRAAEIDAEVIFKATKVDGVYDADPEIYPNAKRYNSLTYAHVLAQDLRVMDSTAIALCKENNIPILVFDLTTRGNIRRAVLGESIGTLVGGSCEIS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_MAIZE
Sequence: MTAILERRESTSLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAALEVPYLNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, 32 kDa thylakoid membrane protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein. Note=PSII is more abundant in mesophyll than bundle sheath cells and more abundant in grana than stroma lamellae in mesophyll cells.
Protein: ULAE_ECO5E
Sequence: MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETDERLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAVEIMDYPLMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMAKAGMVEAA
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 3-epimerase UlaE, L-ascorbate utilization protein E, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: ARGB_BACCN
Sequence: MNECIVIKCGGSMLERLDSTFFHCIEKLKRKYRIVIVHGGGPDIDKILKKLQIPIEKKHGLRVTSQEVMEVVQMVLCGSTNKNLVQNFQRYGLPAIGISGCDGKLLQAKPLNKKIGYVGEVSKVESSLLEGVLNLNYIPIIAPIGIGEEQVYNINADIAAAGIAAALRVKELIFITDVDGLLYEGKLVKKTDEIEILDMIEKEIITGGMIPKVQAALVALRMGIQSVSIVNGTKNFIGLTGEWIGTTVTRGRLQYE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_LACLS
Sequence: MEKETLLYEGKAKKLYFTDDSNVLWVEYCDQATALNGARKEQITGKGALNNQITSLIFEKLNAEGLETHFIKKLSKTEQLNKKVSIIPLEVVLRNVVAGSFAKRFGLEEGIVLEEPIVEFYYKDDALDDPFINDEHVKFLNIASDSEIEFLKKETRKINKILKKIWTEIGLTLVDFKLEFGRLADGSIILADEISPDTSRLWDAKGQHMDKDVFRRNIGDLIETYTEVLNLLEKTK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PSD_PSEA7
Sequence: MSFKDRLFICCQYLLPHHLLSRLVGFAADCRATWFKDRLIAWFARRYQVDMREAQVEDLQAYEHFNAFFTRALKDGARPPAQEPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAELAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNRTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVWAGLVTPPKRELKTFRYDEAARAPIHLEKGAELGRFKLGSTAIVLFGPQQVAFAQGLGAATPVRMGECLALPKQA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TSP2_MOUSE
Sequence: MLWALALLALGIGPRASAGDHVKDTSFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYIPPVNTDDLNRIVKLARRKEGFFLTAQLKQDRKSRGTLLVLEGPGTSQRQFEIVSNGPGDTLDLNYWVEGNQHTNFLEDVGLADSQWKNVTVQVASDTYSLYVGCDLIDSVTLEEPFYEQLEVDRSRMYVAKGASRESHFRGLLQNVHLVFADSVEDILSKKGCQHSQGAEVNTISEHTETLHLSPHITTDLVVQGVEKAQEVCTHSCEELSNMMNELSGLHVMVNQLSKNLERVSSDNQFLLELIGGPLKTRNMSACVQEGRIFAENETWVVDSCTTCTCKKFKTVCHQITCSPATCANPSFVEGECCPSCSHSADSDEGWSPWAEWTECSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRTCSLGKCDTRIRQNGGWSHWSPWSSCSVTCGVGNVTRIRLCNSPVPQMGGKNCKGSGRETKPCQRDPCPIDGRWSPWSPWSACTVTCAGGIRERSRVCNSPEPQYGGKDCVGDVTEHQMCNKRSCPIDGCLSNPCFPGAKCNSFPDGSWSCGSCPVGFLGNGTHCEDLDECAVVTDICFSTNKAPRCVNTNPGFHCLPCPPRYKGNQPFGVGLEDARTEKQVCEPENPCKDKTHSCHKNAECIYLGHFSDPMYKCECQIGYAGDGLICGEDSDLDGWPNNNLVCATNATYHCIKDNCPKLPNSGQEDFDKDGIGDACDEDDDNDGVSDEKDNCQLLFNPRQLDYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLMHNPDQIDQDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNSNQADHDNDGKGDACDSDDDNDGVPDDRDNCRLVFNPDQEDSDGDGRGDICKDDFDNDNVPDIDDVCPENNAITETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDKPSRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTEGQVRTLWHDPKNIGWKDYTAYRWHLIHRPKTGYMRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDA
What is the function of this protein?
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions.  Ligand for CD36 mediating antiangiogenic properties.
What are the official names of this protein?
Thrombospondin-2.
What is the protein family that this protein belongs to?
Belongs to the thrombospondin family.
Protein: PUR6_SCHPO
Sequence: MSEKQVVGILGGGQLGRMMVEAAHRLNIKCIILDAANSPAKQIDGGREHIDASFTDPDAIVELSKKCTLLTTEIEHINTDALAAVTKSVAVEPSPATLRCIQDKYLQKQHLQVFKIALPEFCDAPDQESVEKAGQEFGYPFVLKSKTLAYDGRGNYVVHQPSEIPTAIKALGDRPLYVEKFVPFSMEIAVMVVRSLDGKVYAYPTTETIQKDNVCHLVYAPARLPFSIQQRAQTLAMDAVRTFEGAGIYGVEMFVLQDGETILLNEIAPRPHNSGHYTIEACPTSQFEAHLRAICGLPFSEINTQLSTSTTHALMVNILGTDDPDYVSKIAKRSLSIPGATLHLYGKAESRKGRKMGHVTIISDSPQECERRYQMLLDVKDPVESPVVGIIMGSDSDLSKMKDAAVILDEFKVPYELTIVSAHRTPDRMVTYARTAASRGLRVIIAGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGVPVATVAINNSQNAGILACRILATFQPSLLAAMESFMDNMKEIVLEKADKLEKVGWKNYSA
What are the official names of this protein?
Phosphoribosylaminoimidazole carboxylase, AIR carboxylase, AIRC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.
Protein: SPIKE_CVHNL
Sequence: MKLFLILLVLPLASCFFTCNSNANLSMLQLGVPDNSSTIVTGLLPTHWFCANQSTSVYSANGFFYIDVGNHRSAFALHTGYYDANQYYIYVTNEIGLNASVTLKICKFSRNTTFDFLSNASSSFDCIVNLLFTEQLGAPLGITISGETVRLHLYNVTRTFYVPAAYKLTKLSVKCYFNYSCVFSVVNATVTVNVTTHNGRVVNYTVCDDCNGYTDNIFSVQQDGRIPNGFPFNNWFLLTNGSTLVDGVSRLYQPLRLTCLWPVPGLKSSTGFVYFNATGSDVNCNGYQHNSVVDVMRYNLNFSANSLDNLKSGVIVFKTLQYDVLFYCSNSSSGVLDTTIPFGPSSQPYYCFINSTINTTHVSTFVGILPPTVREIVVARTGQFYINGFKYFDLGFIEAVNFNVTTASATDFWTVAFATFVDVLVNVSATNIQNLLYCDSPFEKLQCEHLQFGLQDGFYSANFLDDNVLPETYVALPIYYQHTDINFTATASFGGSCYVCKPHQVNISLNGNTSVCVRTSHFSIRYIYNRVKSGSPGDSSWHIYLKSGTCPFSFSKLNNFQKFKTICFSTVEVPGSCNFPLEATWHYTSYTIVGALYVTWSEGNSITGVPYPVSGIREFSNLVLNNCTKYNIYDYVGTGIIRSSNQSLAGGITYVSNSGNLLGFKNVSTGNIFIVTPCNQPDQVAVYQQSIIGAMTAVNESRYGLQNLLQLPNFYYVSNGGNNCTTAVMTYSNFGICADGSLIPVRPRNSSDNGISAIITANLSIPSNWTTSVQVEYLQITSTPIVVDCATYVCNGNPRCKNLLKQYTSACKTIEDALRLSAHLETNDVSSMLTFDSNAFSLANVTSFGDYNLSSVLPQRNIRSSRIAGRSALEDLLFSKVVTSGLGTVDVDYKSCTKGLSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGMVLGGLTSAAAIPFSLALQARLNYVALQTDVLQENQKILAASFNKAINNIVASFSSVNDAITQTAEAIHTVTIALNKIQDVVNQQGSALNHLTSQLRHNFQAISNSIQAIYDRLDSIQADQQVDRLITGRLAALNAFVSQVLNKYTEVRGSRRLAQQKINECVKSQSNRYGFCGNGTHIFSIVNSAPDGLLFLHTVLLPTDYKNVKAWSGICVDGIYGYVLRQPNLVLYSDNGVFRVTSRVMFQPRLPVLSDFVQIYNCNVTFVNISRVELHTVIPDYVDVNKTLQEFAQNLPKYVKPNFDLTPFNLTYLNLSSELKQLEAKTASLFQTTVELQGLIDQINSTYVDLKLLNRFENYIKWPWWVWLIISVVFVVLLSLLVFCCLSTGCCGCCNCLTSSMRGCCDCGSTKLPYYEFEKVHVQ
What is the function of this protein?
S1 region attaches the virion to the cell membrane by interacting with host ACE2, initiating the infection (PubMed:15897467, PubMed:29142129, PubMed:19901337).  Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide and activating membranes fusion.  S2 region belongs to the class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
What are the official names of this protein?
Spike glycoprotein, S glycoprotein, E2, Peplomer protein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses spike protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly.
Protein: HATA_DICDI
Sequence: MGNRAFKSHHGHFLSAEGEAVKTHHGHHDHHTHFHVENHGGKVALKTHCGKYLSIGDHKQVYLSHHLHGDHSLFHLEHHGGKVSIKGHHHHYISADHHGHVSTKEHHDHDTTFEEIII
What is the function of this protein?
May act as an intracellular pH sensor that links chemotactic signals to responses in the microfilament system of the cells by nucleating actin polymerization or stabilizing the filaments.
What are the official names of this protein?
Hisactophilin-1, Histidine-rich actin-binding protein 1, HS I.
What is the protein family that this protein belongs to?
Belongs to the hisactophilin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: MURG_HAEIG
Sequence: MKNKKLLVMAGGTGGHVFPAIAVAQTLQKQEWDICWLGTKDRMEAQLVPKYGIPIRFIQISGLRGKGIKALLNAPFAIFRAVLQAKKIIQEEKPDAVLGMGGYVSGPAGVAAKLCGVPIILHEQNAIAGLTNKLLGKIATCVLQAFPTAFPHAEVVGNPVREDLFEMPNPDIRFSDREEKLRVLVVGGSQGARVLNHTLPKVVTQLADKLEFRHQVGKGAVEEVSQLYGENLEQVKITEFIDNMAEAYAWADVVICRSGALTVCEIAAVGAAAIFVPFQHKDRQQYLNAKYLSDVGAAKIIEQADLTPEMLVNYLKNLTRENLLQMALKAKTMSMPNAAQRVAEVIKQYSN
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ETFA_SYNWW
Sequence: MAGTWIFVEQRDGNIRKVTFEMLSEAKKFGDEVAAVVFGKGVEALAPEFAKYGADKVYVVEDDVFANYNTGAYVAQMVAMINEFKPNAVLFAHTFNGRDFASRLAQKLQLGLATDAIKVEVSAGKGVFTRAIYAGKALAKVEVAGEPVLGTIRPGVCEVGNTAGAGAVVKPAVAATAADVYQTVKSFVPTVSARPELTEADVVVSGGRGCKGPDGIKLVEQLADLLGAAVGGSRASIDSGWLGHELQVGQTGKVVNPNLYVAAGISGAIQHLAGMSSSKFIAAINTDTEAPIFNVSDFGVVADLFKVIPTLVSELKK
What is the function of this protein?
Part of an electron transfer flavoprotein involved in syntrophic growth of S. wolfei with butyrate.  Probably receives electrons from butyryl-CoA dehydrogenases, and transfers them to the membrane-bound quinone oxidoreductase Swol_0698.
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRM3_HUMAN
Sequence: MGSRCAKLNTGQSPGHSPGHSTGHGRGHESSMKKLMACVSQDNFSLSSAGEEEEEEEEEGEEEEKEELPVQGKLLLLEPERQEEGHKDNAEAQQSPEPKRTPS
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Protamine-3, Sperm protamine P3.
What is the protein family that this protein belongs to?
Belongs to the protamine P3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FABH_RICCN
Sequence: MTCKIIGCGGYLPSKIVSNDELAKFVDTNDEWIRTRTGITQRHIAGDTEYTSHLALKSAEKAIADAGISVNDIDLIITCTTTPDNSFPSVASKLQGYLGLTNIPSFDLQAVCAGFVYGLQVANSLISSDKYKTILLIGAEKMTSLLDWNDRTTCVLFGDGAGSVILQRSSDDSGLIDSNIFSSGADYDEILYTNGGVSMNGISGKIVMQGQKLFRHAIEKMQQSIKDLLHANQFSVSDIDYFIPHQANIRIINKLAELLNIEEHKVVKTVDKHANCSAASIPLALSTLKASGKIKKGDILLFSAIGAGLTWGSAFIRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG15_BPPH8
Sequence: MSNTAEIINFPNKTEQPGGRMADLSNGYTKVANEIQQLKPRLRLSGREWQCFEAVIWLTYGWNKKQDRVTNTVIAELTGLSDTHVSDALKSLAERKIIFSQKQGMMKIVGVNTDLSAWILDKPETGRKFPKTGKSFPKSGITFPKTVDTQYKNKNSIKRSSSENSDESSDARLKKFLSTHPEAAVYTPSGAKWGSAEDLETAKWISSRVKLINPTCKAPDMTSWSNTVRLMRQIDNRSHQDICALYDWASKHHFWQTNILSPESLRKQWDKLTMQRNAGGEQRAVKPDLDFNNTDWAYGVIR
What is the function of this protein?
This protein is essential for phi-80 DNA synthesis.
What are the official names of this protein?
Replication protein 15.
What is the protein family that this protein belongs to?
Belongs to the phage O protein family.
Protein: ZAPA_ECO24
Sequence: MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKERTRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITEKTNQNFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.