PharMolix/UniProtQA huggingface dataset:
Protein: MDV1_ASPTN
Sequence: MDKHRRDESPSGLSDIVEPDGLLGTGLTSRHIEAFGRKVTTTAGHLMAPSSTEATTGSHYHSAMVDIQRELRRPNTQRRVFSLTQTTPTDLVRSKLSTTEIQSRAISSLPDDLLANIPEDSSSYSLFEGFQASQDDHEYRKVHRRRISKGKKLLKDGDARAALPSTPTDLKKDRDILSRRLDLMGVRKNMCSSEIHEIDNKIANLHNMRKIVLDRLAGLEMEEAELEHELTELDNKLEDLQEEQPESQAAVATPKSSEANEDSFVSEDPAMDASFMSESIYQKMSSPKSIKQRSIRKRSMPILHEHFAPGSQIKEMPAHNDMVTAIDFDFPFGTMVSAALDDTVRVWDLNVGRCTGLLEGHNASVRCLQIEDNIVATGSMDASVKLWDLSRARSVTRDGRVNKDDEGEDTADDAHELFQSTTLEDCYVYSLDAHVDEVTALHFRGDTLISGSADKTLRQWDLVKGRCVQTLDVLWAAAQASTLGGDTQWRPSGRLPDASADFVGALQCFDAALACGTADGMVRLWDLRSGQVHRSLVGHTGPVTCLQFDDVHLVTGSLDRSIRIWDLRTGSIYDAYAYDKPVTSMMFDSKRIVAAAGENVVKVYDKADGHHWDCGAGVGADAEGPSPATVERVRLKDGFLVEGRKDGIVSAWTC
What is the function of this protein?
Involved in mitochondrial fission.  Acts as an adapter protein required to form mitochondrial fission complexes.  Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity).
What are the official names of this protein?
Mitochondrial division protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MDV1/CAF4 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS13_PARL1
Sequence: MARIAGVNIPTNKRVVIALTYIHGIGNTKAKEICGTVGIPAERRVNELTDAEVIQIREAIDRDYLVEGDLRREVSMNIKRLMDLGCYRGLRHRKGLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ADDA_STAA8
Sequence: MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: SECE_STAAR
Sequence: MAKKESFFKGVKSEMEKTSWPTKEELFKYTVIVVSTVIFFLVFFYALDLGITALKNLLFG
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GLGB_HISS2
Sequence: MNKFVSQSTIDTFFDGEHADPFSVLGMHETSNGIEVRVLLPDAEKVFVLSKETKNVLCELLRVDERGFFAGVVPNTHSFFAYQLEVYWGNEAQVIEDPYAFHPMINELDNWLLAEGSHKRPYEILGAHFTECDNVAGVNFRLWAPNAKRVSVVGDFNYWDGRRHPMRFHQSSGIWELFLPKVSLGQLYKFELLDCHNQLRLKADPYAFSSQLRPDTASQIGALPEIVSMTEKRRKANQADQPISIYEVHLGSWRRNLENNFWLDYDQIAEELIPYVKDMGFTHIELLPLSEFPFDGSWGYQPIGLYSPTSRFGTAEGFKRLVNKAHKAGINVILDWVPGHFPSDTHGLVAFDGTALYEHADPKEGYHQDWNTLIYNYGRHEVKNYLASNALYWMERFGLDGIRVDAVASMIYRDYSREDGQWIPNQYGGRENLEAIEFLKQTNHLLGTEIPGVVSIAEESTSFAGVTHPPYEGGLGFHFKWNMGWMNDTLSYMKKDPIYRQHHHSQMTFGMVYQYSENFILPLSHDEVVHGKCSLLGKMPGDAWQKFANLRAYYGYMWGYPGKKLLFMGNEFAQGREWNYQESLDWYLLDEFHGGGWHKAIQDYVRDLNHIYQKNAPLFELDTDPQGFEWLVVDDYQNSVFVFERRSKKDERIIVVSNFTPVLRQNYRFGVNIAGEYLEILNSDAQQYMGSNSTNTSKIVTEDIESHNKAQSISIDIPPLATVYLKLHKVKKVRKMRKTSKVEDTAVKTEKKIAKGKTTRTKKTVADTVSEATEVKPKKTVTKRAVVKKVKNEESAVFPNAEVIAESTSVENNVS
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: BIOC_BACT6
Sequence: MDKQLIAERFAKARNTYTREALVQQQVAGKMIRILTDVLSSAEHLLPEEIAVRFRHIVEFGCGTGSYSRILLHTLHPETLLLNDLCREMEECVGELCSTQTAGRKKDGTEIRVSFLPGDAENFDFPKGTDLITSCSTLQWFNNPETFFLRCHHALTKDGILAFSTFGTKNMHQIRCLTGHGLYYLPIEELQALLSPYFNILHAEEEIVPLSFATPQAVLKHLKQTGVTGTEKRMWTRGRLQAFCEEYIRQFSSPPTGNVTLTYHPIYIIAKNKE
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: ATS10_MOUSE
Sequence: MASACQILRWALALGLGLTFKVTHAFRSQDELLSSLESYEIAFPTRVDHNGAMLAFSPPAFRRQRRGAGATTESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARAHCLYAGHLQGQAGSSHVAVSTCGGLHGLIVADDEEYLIEPLQGGPKGHRGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNESERGQLGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVSHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNGCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRSCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTNDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPALPGTGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFHLRQGPDQAQSLEALGPINASLIIMVLAQAELPALHYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQVVECRNQLDSSAVAPHYCSGHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACQGPMCPPEWATLDWSECTPSCGPGLRHRVVLCKSADQRSTLPPGHCLPAAKPPSTMRCNLRRCPPARWVTSEWGECSTQCGLGQQQRTVRCTSHTGQPSRECTEALRPSTMQQCEAKCDSVVPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR
What is the function of this protein?
Metalloprotease that participate in microfibrils assembly.  Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues (By similarity).
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 10, ADAM-TS 10, ADAM-TS10, ADAMTS-10.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MIAA2_GEODF
Sequence: MKSEEKIKLVSIVGPTASGKTELAVRLAERFDGEIVNADSMQVYRGMDIGTAKPSVSLRSRVTHHLIDIVTPDVNFSASDFRRAADGAIADIHSRGKRVFIVGGTGLYIRALLQGLVDSPSGDEQIRGELNELAKEIGNEGLLQLLAEVDPITAERLHHNDRVRIIRALEVYRQTGRPMSQFRQEHGFAEEMYDCLMLGINVERQELYSRVEKRVDEMVESGLAAEVEELFRLGYARDLKAMRSIGYKEICSFLSGEISLDQAVQLIKRDTRRYAKRQMTWFNKEYGIKWVEYPAAFANICNHVIEFFERGEDHAKSTFQHPGSVP
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 2, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 2, DMAPP:tRNA dimethylallyltransferase 2, DMATase 2, Isopentenyl-diphosphate:tRNA isopentenyltransferase 2, IPP transferase 2, IPPT 2, IPTase 2.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: G3P_JACOR
Sequence: MVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFKYDSTHGKFKVDIVAINDPFIDLNYMVYMFKYDSTHGKFKGTVKAENGKLVINGHAITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSRDAPMFVMGVNHEKYDKSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSAKLWRDGAGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKRVVKQACDGPLKGMLGYTEHQVVSSDFNGDSHSSTFDAGAGIALNDHFVKLVSWYDNEFGYSNRVVDLMVHMASKE
What is the function of this protein?
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively.  Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity).  Modulates the organization and assembly of the cytoskeleton.  Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity).  Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.  Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.  Also plays a role in innate immunity by promoting TNF-induced NF-kappa-B activation and type I interferon production, via interaction with TRAF2 and TRAF3, respectively (By similarity).  Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis.  Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, muscle, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Nucleus. Note=Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal. Colocalizes with CHP1 to small punctate structures along the microtubules tracks.
Protein: PELO_HALS3
Sequence: MQLKDRHTVEGGRERITLVPESLDDLWHLAYVLEPGDFVAGDTHRRIQRNDDQMRDTGGEREHMFVTIDVGDVEFHKFSNRLRVSGTIEDCSREDQLGLHHTLNVAEREELEVEKHWQPDQLNRLNEAVEATDQPDVAIATVEEGEAHIHVVQQYGVDEQGSFTATTGKGEQNDRGRDELFGTLADALARMQADAIILAGPGFTKQDALDHITEEYPDLQETITMVDTSAVGGRGVHEVLKRGAVEDVQEETRIAEESELIDELTTQMATDGKAAYGIDEVQKAVEFGAVEDLLILDERLRLERAGEGDWVDVDVNDLVRTVEQQGGSVTVFSHEFAPGEQLRNLGGIGAVLRYRLD
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1225_ARCFU
Sequence: MIPLVALLVLLTLQASPGDIVSVNVTDTATLTVGDSCMYFVDNLQPSINATPGEYEVKIGINCTPGLKEVYADGSVLAQIDVNETTIDYQAYAASLEKENLALQKEVESLKEKLKISQEQIETLKSQLEDLQNKAKMLGIQNELQKQQIEELQKKLERAKTELQKKKSDLDELEEKIRELNRQSSIYRLATFFMVSLFVGSFVALVFVARKE
What are the official names of this protein?
Uncharacterized protein AF_1225.
What is the protein family that this protein belongs to?
To A.fulgidus AF_0540.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CGHB_CALJA
Sequence: MEMLQGLLLCLLLSTGGAWASKEPLRPLCRPVNAILAAEKEGCPVCVAFNTTICAGYCSSMVRVLQTILPPLPQSVCNYHELRFTSVRLPGCRPGVDPVVSMPVALSCRCGLCRRSYSDCGSLRNEPLGCDYSTFQDSSSKDPPRNLTSPSQLLEPADPPLVPQ
What is the function of this protein?
Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
What are the official names of this protein?
Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: LRGB_STAAC
Sequence: MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LSY12_CAEEL
Sequence: MGKKRKPSPERSSDEDEVSTPSPKDRTARPTAAARRENVALSQAVALSLEDASNFCSLAFSLERIKREPVDTDYDDPNQPGPSSVPVSARTDHVLPIRFKIKAEPQEYDSDEYGKDHGAVQIANKEVPAISPIEEVSQKRRGRPRKTDAAQHLFFPHVSIKQEPDDGFINFHESRCVGIAQDPEMQHLHDVNESHSSEIAIFRETKKITERKKKKTEAEKLWDNMSLTEKEVFQSHTRRRRTTRLPIIQNFEETEEGCIVEVPIPLIDLDNDAVESVTGPQHENVTVSENVLSTESTDQEVTETKRLHDSSRDFNPPRIQDTPSTVIRPEGDQKDPMSSTSSKRRNTNNSRCASLLSNPHSTPVTRLMRGILDSENSDNDEMLSNDQSEIAKRPRTPRPRYSPEAQRRTNSRLSALTIDTNRSNDLNVDGSAPSSSSAASCGLSTPDPDRTSQQRRKGNQSAARSRKIKTPSPPLSQEDEPMELDSDDDPVNELDNLPIVIDDPSYVLTKEHKEIFEQVKKSVSDRNEFSPAQISEIYRSSKGEQARLPERIHFGAFIMKTWYGSPFPAEFINVKKLFICEFCFFYARSDEIMQNHAKKCMLRAPPGLEIYRKGDISVFEVDGRLQKEYCQTLCLVSRMFLESKTVFYDTEPFFFYIVTINDDIGCHFAGYFSKEKYEPDVNNLSCIMTLPCYQEMGLGRFLIDISYALSRKEKWFGGPEQPLSELGRKAYGGYWRTTIASCLGRLKDELEFGSGISIKMIADDTGVNCHDILEVVCSLGWAKPVDPDEKNHYKLEWDVDWDMVSIILRESEASKETKVQYDPECLDWVPRKMRPSMDGYHELSKEEIEQDEQRRKSIQKTPVHVSMEKATPTSTTSLPVGSVKKELRSRGHNRSVGRNLKHEVNRKVKVPEWAAARDLTDEEITVEENKKQQKQNRKIFTRCADSVLDKSNIREETPEDDEPGPSTKPSGKRQRGNKCNNTESEPNPSGRKTSATSSGRGKYRNRRTDGTEEEEEDDDPTDSEPLTTDDEKPFETSVNKEKNEKSRRGKKVSKKRRSVAGKKFPPNFGVRDRDEPKKAENSEDGEGLESKPGPSTEMILVEKVEEEEAKVTVSDINMQASESKIEGIEQTSEVDIPKSDEDHQSTEAYDRVEDEVPITDYNIPTPDSYHSSPPHSPTPSPQPQLMQAQQNIYQDNDCHFAENDSKPPHLVSEVDDPAAPQPTVTLQSGPSDAPPLSHNSVDGYSTGDDDAPPNLSPQIGKSENNEEEMPLIAPIVQHNGITHHEESTAQHYHDSMNAGPSTSSHVTPQMSMINTTPQQPPFSHPNSQQQATPGSGGVPSCGPAYTHHTPEQQSQQFMSPPMAGMPASVASNHSIHNSNSIEMVGGPASLQHTPQQYEMGHSMAQMSQESAIGGINTVPSIEQQNQLMLQHHQFSSPPAAPPPSQQQQVVQPPIPPAPTTANGRRRSESAATQRTKARQQHQHQQQQPQQPQQRIAAPGVPQGVHPQMQFPMNAMNMMPAYPPFYPYTNYPNIWQPPYQNYPYNQVDYQQPWLYNNGHIPHQTNGTATNQFHPGHMGYFPNNNGR
What is the function of this protein?
Probable histone acetyltransferase (Probable).  Required to initiate and then maintain lateralized gene expression in the ASE sensory neurons (PubMed:20923973).  Involved in determining cell fate in the ASE neurons (PubMed:20923973).
What are the official names of this protein?
Histone acetyltransferase lsy-12.
What is the protein family that this protein belongs to?
Belongs to the MYST (SAS/MOZ) family.
Protein: RECB_ECOLI
Sequence: MSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGLGGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNPLYERLLEEIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLRYQACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETLASRHAQIVARIDTVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIDKISAWAEEETNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVITRALAEIRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQQYRIFRRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSAPGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAMKMWLMEGESCGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQVRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLNALDIETLNNDEHAWDVVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGERRLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVTIHKSKGLEYPLVWLPFITNFRVQEQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAEDLRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTCIEALCDDDIAWQTAQTGDNQPWQVNDVSTAELNAKTLQRLPGDNWRVTSYSGLQQRGHGIAQDLMPRLDVDAAGVASVVEEPTLTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNWVREKLELGGFESQWEPVLTEWITAVLQAPLNETGVSLSQLSARNKQVEMEFYLPISEPLIASQLDTLIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGEDSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYEHHFGGVIYLFLRGVDKEHPQQGIYTTRPNAGLIALMDEMFAGMTLEEA
What is the function of this protein?
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair.  Binds to DSBs and unwinds DNA via a rapid (>1 kb/second) and highly processive (>30 kb) ATP-dependent bidirectional helicase.  Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator, 5'-GCTGGTGG-3') sequence from the 3' direction.  Cuts ssDNA a few nucleotides 3' to Chi site, by nicking one strand or switching the strand degraded (depending on the reaction conditions).  The properties and activities of the enzyme are changed at Chi.  The Chi-altered holoenzyme produces a long 3'-ssDNA overhang which facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair.  Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination (PubMed:4562392, PubMed:4552016, PubMed:123277).  In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.  The RecBC complex requires the RecD subunit for nuclease activity, but can translocate along ssDNA in both directions.  Probably interacts with a component of retron Ec48 which moniters RecBCD stability; when RecB is missing or impaired the retron is activated and becomes toxic (Probable).
What are the official names of this protein?
RecBCD enzyme subunit RecB, Exodeoxyribonuclease V 135 kDa polypeptide, Exodeoxyribonuclease V beta chain, Exonuclease V subunit RecB, ExoV subunit RecB, Helicase/nuclease RecBCD subunit RecB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: T5AT_TAXWC
Sequence: MEKTDLHVNLNEKVMVGPSLPLPKTTLQLSSIDNLPGVRGSIFNALLIYNASPSPTMVSADPAKLIREALAKILVYYPPFAGRLRETENGDLEVECTGEGAMFLEAMADNELSVLGDFDDSNPSFQQLLFSLPLDTNFKDLPLLVVQVTRFTCGGFVVGVSFHHGVCDGRGAAQFLKGLAEMARGEVKLSLEPIWNRELVKLDDPKYLQFFHFEFLRAPSIVEKIVQTYFIIDFETINYIKQSVMEECKEFCSSFEVASAMTWIARTRAFQIPESEYVKILFGMDMRNSFNPPLPSGYYGNSIGTACAVDNVQDLLSGSLLRAIMIIKKSKVSLNDNFKSRAVVKPSELDVNMNHENVVAFADWSRLGFDEVDFGWGNAVSVSPVQQQCELAMQNYFLFLKPSKNKPDGIKILMFLPLSKMKSFKIEMEAMMKKYVAKV
What are the official names of this protein?
Taxadien-5-alpha-ol O-acetyltransferase, Taxa-4(20),11(12)-dien-5alpha-ol-O-acetyltransferase, Taxadienol acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: S10A5_RAT
Sequence: METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKTELSLAEKMKESSIDNLMKSLDKNSDQEIDFKEYSVFLTTLCMAYNDFFLEDNK
What is the function of this protein?
Binds calcium, zinc and copper.  One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus 1 zinc ion.  Calcium and copper ions compete for the same binding sites.
What are the official names of this protein?
Protein S100-A5, Protein S-100D, S100 calcium-binding protein A5.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
Protein: PMTF_ARATH
Sequence: MGNYRWPSKLSKLSLRAKQTNLYRVILIAILCVTFYFVGVWQHSGRGISRSSISNHELTSVPCTFPHQTTPILNFASRHTAPDLPPTITDARVVQIPSCGVEFSEYTPCEFVNRSLNFPRERLIYRERHCPEKHEIVRCRIPAPYGYSLPFRWPESRDVAWFANVPHTELTVEKKNQNWVRYEKDRFLFPGGGTMFPRGADAYIDEIGRLINLKDGSIRTAIDTGCGVASFGAYLMSRNIVTMSFAPRDTHEAQVQFALERGVPAIIGVLASIRLPFPARAFDIAHCSRCLIPWGQYNGTYLIEVDRVLRPGGYWILSGPPINWQRHWKGWERTRDDLNSEQSQIERVARSLCWRKLVQREDLAVWQKPTNHVHCKRNRIALGRPPFCHRTLPNQGWYTKLETCLTPLPEVTGSEIKEVAGGQLARWPERLNALPPRIKSGSLEGITEDEFVSNTEKWQRRVSYYKKYDQQLAETGRYRNFLDMNAHLGGFASALVDDPVWVMNVVPVEASVNTLGVIYERGLIGTYQNWCEAMSTYPRTYDFIHADSVFSLYKDRCDMEDILLEMDRILRPKGSVIIRDDIDVLTKVKKITDAMQWEGRIGDHENGPLEREKILFLVKEYWTAPAPDQSSDP
What are the official names of this protein?
Probable methyltransferase PMT15.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RNZ_STRU0
Sequence: MELQFLGTGAGQPAKQRNVSSLVLKLLDEINEVWMFDCGEGTQRQILETSIKPRKIQKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDIEIFGPLGIKSFVQNSLAISGTRLPYKIHFHEFTDKDMGKIMETDKFLVYAEKLAHTIFCMGYRVVQKDLEGTLDAEALKKAGVPFGPLFGKIKNGQDIVLDDGRQILAKDYISEPKKGKVITILGDTRKTPASQRLALNADVLVHESTYGKGDDRIARNHGHSTNMQAAQIAKDANVKRLLLNHVSARFLSRDCRQMEKDAASLFENVKIVKDLEEVTI
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.