PharMolix/UniProtQA huggingface dataset:
Protein: CC184_HUMAN
Sequence: MEDGLLEIMTKDGGDMPAPLEVSTVPAVGDVISGEYNGGMKELMEHLKAQLQALFEDVRAMRGALDEQASHIQVLSDDVCANQRAIVSMCQIMTTAPRQGGLGVVGGKGSFQSDPQEPETPSPGIGDSGLLGRDPEDEEEEEEEKEMPSPATPSSHCERPESPCAGLLGGDGPLVEPLDMPDITLLQLEGEASL
What are the official names of this protein?
Coiled-coil domain-containing protein 184.
Protein: AOX_YARLI
Sequence: MTVRDWANRGQTYVNARAPNLLGRFRSTDDEDENNPSTELATDTTSAYGSTAASVVTMANSKPDDVSLYATSSHHHEYFTGSAWIHPVYTKEQMDALEVNHRKTETFSDRVALRAILLMRIIFDLCTGYKHPKEGEAHLPKFRMTTRQWLDRFLFLESIAGVPGMVAGMIRHLHSLRALRRDRAWIESLVEEAYNERMHLLTFLKLQKPSVQMRTGLLIGQIIFYNLFFISYLISPATCHRFVGYLEEEAVITYTRCLEDIDAGRLPELASMEVPDIARTYWHMEDDCTMRDLIQYVRADEAKHCEVNHTFGNLHQTSDRNPFALVIDNGRPQPSKDLTTFRSVGWRRDEIAN
What is the function of this protein?
Catalyzes cyanide-resistant oxygen consumption.  May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity).
What are the official names of this protein?
Alternative oxidase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the alternative oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Protein: SPDYC_HUMAN
Sequence: MLWAIPELGSPCPISISYEMSDSQDPTTSPVVTTQVELGGCSRQGGGNGFLRFRQHQEVQAFLSLLEDSFVQEFLSKDPCFQISDKYLLAMVLVYFQRAHLKLSEYTHSSLFLALYLANDMEEDLEGPKCEIFPWALGKDWCLRVGKFLHQRDKLWARMGFRAVVSRQCCEEVMAKEPFHWAWTRDRRPHHGGVQRVCPQVPVRLPRGPGLSPPHCSPCGLPQHCSSHLLKPVSSKCPSLTSECHRPPSQNYLSRVKNAWGGDFLIVLPPQMQLEPGTYSLRIFPKPPARPGH
What is the function of this protein?
Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2.  Involved in the spindle-assembly checkpoint.  Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores.  Required for the correct localization of the active form of Aurora B in prometaphase.
What are the official names of this protein?
Speedy protein C, Rapid inducer of G2/M progression in oocytes C, RINGO C, hSpy/Ringo C.
What is the protein family that this protein belongs to?
Belongs to the Speedy/Ringo family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with tubulin gamma during interphase. During mitosis, enriched at the spindle poles and the midbody during telophase.
Protein: EFG1_VIBPA
Sequence: MARKTPIEHYRNIGICAHVDAGKTTTTERILFYTGLSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWRGMEAQFPEHRVNIIDTPGHVDFTIEVERSLRVLDGAVVVFCGSSGVEPQSETVWRQADKYHVPRMVFVNKMDRAGADFLRVVDQIKNRLGANPVPIQLNVGAEEDFRGVIDLIKMKMINWNDADQGMSFTYEDIPADMIDLAEEWRNHMIESAAEASEELMDKYLEEGELTEAEIKQALRTRTLNNEIVLATCGSAFKNKGVQAVLDAVIEFLPSPSDVPAIKGVDEKDNEIERHADDNEPFSALAFKIATDPFVGTLTFMRVYSGVVNSGDAVYNSVKEKKERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDQSHKVILERMEFPEPVIQIAVEPRSKADQEKMGIALGKLAAEDPSFRVETDDETGQTLISGMGELHLDIIVDRMKREFSVDCNVGKPQVAYRETIRGKAEVEGKFVRQSGGRGQYGHVWVKLEPSEPGEGFVFVDEIVGGVIPKEYISSVAKGIEEQMNSGVLAGYPVLDIKATLFDGSYHDVDSSEMAFKIAGSMAFKKGALEAQPVILEPMMNVEVTTPEDWMGDVVGDLNRRRGMIEGMDEGVAGLKIIRAQVPLSEMFGYATDLRSATQGRASYSMEFNEYAEVPKNFADKIIAERGY
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_HELPH
Sequence: MARYRGAVERLERRFGVSLALKGERRLSGKSALDKRAYGPGQHGQRRAKTSDYGLQLKEKQKAKMMYGISEKQFRSIFVEANRLDGNTGENLIRLIERRLDNVVYRMGFATTRSSARQLVTHGHVLVDGKRLDIPSYFVRSGQKIEIKEKTKSNPQVVRATELTAQTGIVPWIDVEKDKKYGIFTRYPEREEVVVPIEERLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: R13A4_ARATH
Sequence: MVSGSGICSKRVVVDARHHMLGRLASITAKELLNGQKVVIVRCEEICLSGGLVRQKMKYMRFLRKRMNTKPSHGPIHFRAPSKIFWRTVRGMIPHKTKRGAAALARLKVYEGVPTPYDKIKRMVIPDALKVLRLQAGHKYCLLGRLSSEVGWNHYDTIKELETKRKERAHVVYERKKQLNKLRVKAEKVAEEKLGAQLDILAPVKY
What are the official names of this protein?
60S ribosomal protein L13a-4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MATK_OTAAZ
Sequence: MEEIQRYFQLERSHQHDFLYPLIFQEYIYTFAHDRGCNRSILSENPCYENKSSLLIVKRLITRMCQQNHFLISSNDFNQNPFWGRNKNFDFQIISEGFALIVEIPFSLRLRASLEEKKIVTFQNLRSIQAIFPFLEDSFSHLNFVLDISIPHSIHLEILVQTLRYWVKDASSLHLLRFFLNEYCNSNSLITPKKVSSSFSKRNQRFFLFLYNSHVCEYESIFVFLRKQSSHLRSTSSGLLLERIYFYAKMERLVNLFVKVKDFQVNLWLVKEPCMHYVRYQRKSILASKGVSLLINKWKSYLVAFWQWHFSMWFHPRRISINQLSNHSLEFLGYLSSVRMNPSVVRSQILENSFLINNALKKFDTLVPINPLIASLAKAKFCNVLGHPISKPVWADFSDLNIIDRFGHISRNISHYYSGSSXKNSLYRIKYILRLSCARTLARKHKSTVRVFLKRLGSELLEEFLMSEEDVLSLTFPKASSTFWGVYRSRIWYLDIISINDLANHKSKF
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CRIS3_MOUSE
Sequence: MALMLVLFFLAAVLPPSLLQDNSQENSLEKLSTSKKSVQEEIVSKHNQLRRKVSPSGSDLLNMEWNYDAQVNAQQRADKCTFSHSPIELRTTNLKCGENLFMSSYLVPWSSVIQGWYNESKGLIFGVGPKQNVSVVGHHTQVVWKSNLQVACGVAECPENPLRYFYVCRYCPVLNYSGHYPSRPYLAYTARAPCASCPDRCEDGLCTKSCQYKDMSFWCKRLEYVCKHPGLKKRCLATCQC
What is the function of this protein?
This protein is supposed to help spermatozoa undergo functional maturation while they move from the testis to the ductus deferens.
What are the official names of this protein?
Cysteine-rich secretory protein 3, CRISP-3, Acidic epididymal glycoprotein 2, Sperm-coating glycoprotein 2, SCP 2.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Stored in secretory granules of granular convoluted tubules cells.
Protein: BFR_MYCLE
Sequence: MQGDPDVLRLLNEQLTSELTAINQYFLHSKMQENWGFTELAERTRVESFDEMRHAEAITDRILLLDGLPNYQRIGSLRVGQTLREQFEADLAIEYEVMSRLKPGIIMCREKQDSTSAVLLEKIVADEEEHIDYLETQLALMGQLGEELYSAQCVSRPPS
What is the function of this protein?
Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex (By similarity).  Probably plays a crucial role in the intracellular existence of this organism by functioning as a temporary depository for iron in iron deprivation.
What are the official names of this protein?
Bacterioferritin, BFR, Major membrane protein II, MMP-II.
What is the protein family that this protein belongs to?
Belongs to the bacterioferritin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=Soluble or peripheral membrane protein.
Protein: TRHO_STRPQ
Sequence: MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADEGINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLEDNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKDPEVQGELWDGAMYVFDDRISVPINHVNPTVVSKDYFDGTPCERYVNCANPFCNKQIFASEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: NOE1_HUMAN
Sequence: MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTKLSAAGGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDESGLWAVYATNQNAGNIVVSRLDPVSLQTLQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQILYNVTLFHVIRSDEL
What is the function of this protein?
Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1.  Inhibits RTN4R-mediated axon growth cone collapse (By similarity).  May play an important role in regulating the production of neural crest cells by the neural tube (By similarity).  May be required for normal responses to olfactory stimuli (By similarity).
What are the official names of this protein?
Noelin, Neuronal olfactomedin-related ER localized protein, Olfactomedin-1.
What are the subcellular locations of this protein?
Secreted. Synapse. Endoplasmic reticulum. Cell projection, axon. Perikaryon.
Protein: DRC11_CHLRE
Sequence: MWREAMMELLDQLEAENPEDPALAPKDLSEWACIYIKYLQIMRKLETAYDQMVHPQKRQDMRKALEACIGRMLEIRHWMVKLNRGLDFINLDDILVDLKLGPEVLEVPVPKYFIEDRAKELDDRDKFLEALIEKYNVKGPAASPIIRIGAPLGEDEAILMIQKNERGRQARERARLAAITKRQRQIEDRRVRLGVTLSHEEAARKIQAAIRGFLWRRRIKKEADKELMFIGMKPKPRDPKRDPQMGEAKNLMRRKRVQLEHGREYDEAIVNLKGKVRELEGQDMRETIQDKVNAWFVEKRNPDTGEYPDFPDPDDGGSRAILNPPPPSLASLLEDAAGDGKGKGKDGKGDAKKDAKKDPKKDKKGGGDEPQAEEQKIGAVFIPAIEAAVQEFVAKWQDRDEADNFHQKYDAELVKDELRPIVFEEIRLQVDGEMRVLLQNLKDLVEAERAAKLGKKGKKKKGKKKEPFSRIKKELLKEAKTLAPGERVLVLGNSREPYLCAKKDEKDAAGDGKGKGKDGKGGGKPGTAGSKPGTADKKKKGGKKKSLCSDWSCGA
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (PubMed:25411337, PubMed:23427265).
What are the official names of this protein?
Dynein regulatory complex protein 11, Flagellar-associated protein 82.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. DRC11 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: RS19_CHLT2
Sequence: MSRSLRKGPFVDHHLLKKVRDMNALEKKTPIKTWSRRSMITPEMIGHTFEVHNGRKFLTVFVSETMVGHKLGEFSPTRMFKSHPVKKG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: FTSH_THET8
Sequence: MPRAPFSLLALVLGLAFLAWAFSLAGTVGAPSGTVNYTTFLEDLKAGRVKEVVVRAGDTRIQGVLEDGSAFTTYAASPPDNATLEGWMARGVSVRVEPPQGQNALGFLWPLLLVGLLIGALYYFSRNGRAGPSDSAFSFTKSRARVLTEAPKVTFKDVAGAEEAKEELKEIVEFLKNPSRFHEMGARIPKGVLLVGPPGVGKTHLARAVAGEARVPFITASGSDFVEMFVGVGAARVRDLFETAKRHAPCIVFIDEIDAVGRKRGSGVGGGNDEREQTLNQLLVEMDGFEKDTAIVVMAATNRPDILDPALLRPGRFDRQIAIDAPDVKGREQILRIHARGKPLAEDVDLALLAKRTPGFVGADLENLLNEAALLAAREGRRKITMKDLEEAADRVMMGPAKKSLVLSPRDRRITAYHEAGHALAAHFLEHADGVHKVTIVPRGRALGFMMPRREDMLHWSRKRLLDQIAVALAGRAAEEIVFDDVTTGAENDFRQATELARRMITEWGMHPEFGPVAYAVREDTYLGGYDVRQYSEETAKRIDEAVRRLIEEQYQRVKALLLEKREVLERVAETLLERETLTAEEFQRVVEGLPLEAPEEAREEREPPRVVPKVKPGGALGGA
What is the function of this protein?
Degrades preferentially unfolded substrates in a processive, ATP-dependent manner, usually after hydrophobic residues.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: S39AB_HUMAN
Sequence: MLQGHSSVFQALLGTFFTWGMTAAGAALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMPHLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIGRAGLLSDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG
What is the function of this protein?
Functions as a cellular zinc transporter.
What are the official names of this protein?
Zinc transporter ZIP11, Solute carrier family 39 member 11, Zrt- and Irt-like protein 11, ZIP-11.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Nucleus. Cytoplasm. Golgi apparatus.
Protein: MTOX_SHISS
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEDDPIFVRSGVINLGPADSAFLANVAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDDDGVTIETVDGEYQAKKAIVCAGTWVKDLLPEQPVQPVRKVFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: MOAC_RHORT
Sequence: MTDPAPATADGLTHFDTAGNAVMVDVSAKDETERVAVAGGCVEMAPATLRAIIERGLKKGDVLSVAQLAGIMGAKRTPDLIPLCHPLALTKVAVELTPDPDHDRVVITATCALRGRTGVEMEALTAVAVAGLTVYDMCKAVDKGMRLTDIRLLSKTGGKSGTWTAS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PSAM_EUGVI
Sequence: MTITSTQVYIALLTALIPAFFALKLGKELSK
What are the official names of this protein?
Photosystem I reaction center subunit XII, PSI-M.
What is the protein family that this protein belongs to?
Belongs to the PsaM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HCAD_ECOLC
Sequence: MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYERPPLSKSMLLEDSPQLQQVLPANWWQENNVHLHSGVTIKTLGRDTRELVLTNGESWHWDQLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIIGAGTIGLELAASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGEKVELTLQSGETLQADVVIYGIGISANEQLAREANLDTANGIVIDEACRTCDPAIFAGGDVAITRLDNGALHRCESWENANNQAQIAAAAMLGLPLPLLPPPWFWSDQYSDNLQFIGDMRGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRPIRKWIQSGKTFDAKLLIDENIALKSL
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: DXR_BURP6
Sequence: MQKRLTLLGSTGSIGDSTLDVVARHPERFAVHALTAHRNGEKLVAQCLRFAPDVAVVGDAETAARVEAQLRAAGSRTQVAYGKQALVDVSKSDGCDTVVAAIVGAAGLAPSLAAARAGKRILLANKEALVMSGAIFMDAVRDHGAILLPVDSEHNAIFQCMPRDAAEHGGIAKIIVTASGGPFRTREPATLASVTPDEACKHPNWVMGRKISVDSATMMNKGLEVIEAHWLFGLPSERIDVLIHPQSVIHSLVSYRDGSVLAQLGNPDMRTPIAHALAFPERVDAGVAQLDLAQIATLTFEKPDYARFPCLALAIDALEAGGVASAALNAANEIAVDAFLSRRIRFTAIAQTVGAVLDGLSNRTPGGLDDVIEADAAARRAATAFIGKLPAPGVERAA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: SFC1_SCHPO
Sequence: MNSLKISDNEYALIEHPGFANNKDAFFQTLGGVQSIQKACQTSFQNPKQALLELNLRPKDKYHHPVQARVQSRNDLLVTIKKMDNSVQNVSRIRQVFLFRDMADFQYSTQNSPFVQKLDSTLRVLDYNAINKFSIDLTPVQRKHVDMPPPPVFSQTSLPMSYNFLQNPLVGRVRLPNGKTTIVNLKGQCRVWIITTNMGVESVPTCRHSKLGEPSKTIQEVIEALKPLFEKRPVWTRRALLNHLDPSYTHYLKFALPYLSYLWTSGPFRDTYTRFGYDPRKDSNAAAYQALFFKLKLNGKHKGTKTHVFDGKTLFPTNRVYQVCDIVDPTIAPLLKDTQLRSECHRDTGWYRSGRYYKVRDLMREKLFALIEGEMPSEVAVNMILNAEEVEESDRYSNFDEQDNTDLNDTVRGLNTSATDDRINDLMRNLMKRSQEHEGFEDLEEIDDDYDDIFGD
What is the function of this protein?
TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements.  Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function.  Part of the tauA domain of TFIIIC that binds boxA DNA promoter sites of tRNA and similar genes.  Participates in the interconnection of tauA with tauB via its contacts with sfc3 and sfc6.  Serves as a scaffold critical for tauA-DNA spatial configuration and tauB-DNA stability.  Localizes to chromatin insulator sequence without recruiting RNA polymerase III and plays a role in nuclear organization.
What are the official names of this protein?
Transcription factor tau subunit sfc1, TFIIIC subunit sfc1, Transcription factor C subunit 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYC_DESRM
Sequence: MQIYNTLARAKEEFIPRDKGHVSMYVCGPTTYNFIHLGNARPLVFFDTVRRYFLYKGYKVDYVQNFTDVDDKIINRAAEEKIDPLELAQKYIQEFFVDADALNVMRADTHPKVSEHIEEIIDLIKRLEDQGHAYVVDGDVYFAVRSFAEYGKLSGRSLEDMQAGARVEVDPRKKDPMDFALWKAAKPGEPSWDSPWGSGRPGWHIECSAMAEKYLGNGFDIHGGGFDLIFPHHENEIAQSEAACKAPFARYWMHNGFITINQEKMSKSLGNFFLVREILAKFPPDVVRWYLLSTHYRSPLDFDDEKLVMSGKGLERIKTALRLLYEAMDLPVYEGEDIQGAENFEETLQRIRLEFEKAMDDDFNTALAISYFFDLAKEVNIYVGKLNSKVTLEMRKILDQAHTLIKDFNRVLGILKEDKMTGKLLIEMAGADDTLTEGLVQLIIKIRQEARSKKDWSTADAIRDGLKELGVVLEDTPQGVRWKKQG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_BACSU
Sequence: MSEKKEIATFAGGCFWCMVKPFDEQPGIEKVVSGYTGGHTENPTYEEVCSETTGHREAVQITFHPDVFPYEKLLELFWQQIDPTDAGGQFADRGSSYRAAIFYHNDKQKELAEASKQRLAESGIFKDPIVTDILKAEPFYEAEGYHQHFYKKNPAHYQRYRTGSGRAGFISEHWGAK
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.  May deal with oxidative damage to alpha/beta-type SASP in spores.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: DNAK_SALSV
Sequence: MGKIIGIDLGTTNSCVAIMDGTQARVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPYKIIGADNGDAWLDVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKEVGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDTRLINYLVDEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDINDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTPLITKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRASDNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEEEIQKMVRDAEANAESDRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALSALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQAGSADASANNAKDDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: AMPP1_TALSN
Sequence: MLFSCRAPSLLQRTALSSPLRLFAPCRPSFSRTFVTTTVRFSVEMETVNTSERLAQLRELMKQNNLDVYIVPSEDSHQSEYIAHCDARREFISGFTGSAGTAVISTTAAALSTDGRYFNQAAKQLDSNWKLLKRGLEGVLTWQEWTAEQAEGGKIVGVDPSVITAASARKLSETLEKGGSKLVGIEQNLVDQIWGTHRPQRPSEKVKIHPIEYAGKPFQEKIADLRKELKTKKRAGFIVSVLDEIAWLFNLRGNDIPYNPVFFSYAVITPDTVDLYIDDEKLSPEVKVHLGSDVVIKPYESIFADAKALSAKAPLTESGAPMKYLTSNKASWALSLSFGGEKKLDEARSPISDAKAIKNEVELKGMRDCHIRDGAALTEYFAWLENELINKKSTLDEVDGADKLEQIRSKHDKFVGLSFDTISSTGPNAAVIHYKPEKGVCSVIDPNAIYLCDSGAQYLDGTTDTTRTFHFSTPTEMEKKAFTLVLKGLIALDTAVFPKGTSGFALDALARQHLWRQGLDYLHGTGHGVGAYLNVHEGPIGVGTRIQYSEVSLSPGNVISDEPGYYEDGKFGIRIENIIMAREVETPYKFGDKPWLGFEHVTMTPIGQNLIETSLLSKEERQWVDNYHAEVWEKTSGFFKQDELTLNWLKKETQPLK
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: GYRA_HALH5
Sequence: MAEQDQSRVKEINISQEMKTSFMDYAMSVIVSRALPDVRDGMKPVHRRILYAMNELGMTSDKAYKKSARIVGEVIGKYHPHGDSAVYETMVRMAQDFSYRYMLVDGHGNFGSIDGDAAAAMRYTEARMSKISMELVRDINKDTIDYQDNYDGSEKEPVVMPSRFPNLLVNGASGIAVGMATNIPPHQLGEVIDGVLALSKNPDISVPELMEHIPGPDFPTGAEILGRSGIRKAYQTGRGSITLRAKTEIEEHHGKQRIIVHEIPYQVNKAKLIEKIAELVRDKKIDGITDLRDESDRNGMRIVIEVRKDANANVLLNNLYKQTALQTSFGINLLALVEGQPKVLNLKECLEHYLAHQVIVIRRRTAFELRKAEARAHILEGLRIALDHLDEVISLIRSSQTTEIARNGLMERFELSYEQAQAILDMRLQRLTGLERDKIEAEYKELIERIAELKAILADHEKVLDIIREELLELKEKYNDERKTAISASEDMFEDEDLIPRQNVVITLTHHGYIKRLPISTYRSQKRGGRGIQGMGTNEDDFVQHLFTTNSHHTILFFTNKGKVYRLKGYEIPELGRTAKGIPIINLLQIEQDEYISTIIPIEEFTEDHYLFFMTKDGIAKRTQLSSFANIRRGGLFAINLREGDELHGVRLTNGDKEVIVGTRQGMAIRFHETDVRLMGRTATGVKGISLTGDDHVVGMDIVEDGQDVLIVTEKGFGKRTPIADYRIQTRGGKGIKTCNITEKNGPLVSLKVVSVDHDLMIITASGIIIRLHVKDISVTGRITQGVTLIRVAEGEEVATVARVDIEDDELDEDESIEEERDDRSEVEQGENE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
Protein: LPQW_MYCTU
Sequence: MGVPSPVRRVCVTVGALVALACMVLAGCTVSPPPAPQSTDTPRSTPPPPRRPTQIIMGIDWIGPGFNPHLLSDLSPVNAAISALVLPSAFRPIPDPNTPTGSRWEMDPTLLVSADVTNNHPFTVTYKIRPEAQWTDNAPIAADDFWYLWQQMVTQPGVVDPAGYHLITSVQSLEGGKQAVVTFAQPYPAWRELFTDILPAHIVKDIPGGFASGLARALPVTGGQFRVENIDPQRDEILIARNDRYWGPPSKPGIILFRRAGAPAALADSVRNGDTQVAQVHGGSAAFAQLSAIPDVRTARIVTPRVMQFTLRANVPKLADTQVRKAILGLLDVDLLAAVGAGTDNTVTLDQAQIRSPSDPGYVPTAPPAMSSAAALGLLEASGFQVDTNTSVSPAPSVPDSTTTSVSTGPPEVIRGRISKDGEQLTLVIGVAANDPTSVAVANTAADQLRDVGIAATVLALDPVTLYHDALNDNRVDAIVGWRQAGGNLATLLASRYGCPALQATTVPAANAPTTAPSAPIGPTPSAAPDTATPPPTAPRRPSDPGALVKAPSNLTGICDRSIQSNIDAALNGTKNINDVITAVEPRLWNMSTVLPILQDTTIVAAGPSVQNVSLSGAVPVGIVGDAGQWVKTGQ
What is the function of this protein?
May directly or indirectly regulate the accessibility of the key branch point intermediate, monoacyl phosphatidylinositol tetramannoside (AcPIM4), to the elongating alpha-1,6 mannosyltransferases which could regulate the lipoarabinomannans (LAMs) biosynthesis.
What are the official names of this protein?
Probable monoacyl phosphatidylinositol tetramannoside-binding protein LpqW.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.