PharMolix/UniProtQA huggingface dataset:
Protein: MUTL_BACP2
Sequence: MAKIIQLSDDLSNKIAAGEVVERPASVVKELMENAIDASSTVVEIDVEEAGLSSIRMIDNGVGIDAEDCKLAFQRHATSKIKDENDLFRVRTLGFRGEALPSIASVSHLEMKTSTGEGAGTHLVLQGGKIISEKKTSGRRGTEIVVTNLFYNTPARLKYMKTVHTELGNISDVVNRIALAHPEVSIRLRHQGKVLLQTNGNGDVRHVLAAIYGTAVAKKMVPLHVQSLDFEVKGYISLPEVTRASRNYMSSVVNGRYVKHFPLVKAVHEGYHTLLPIGRHPITFIEMKMDPILVDVNVHPSKLEVRLSKEQELHELIKQGIKDVFQKQQLIPSASVPKKAPMPAIKNEQQSLTFDAKKGNTNEMETPLSYEPEPLESVVYETNQMSTYGMPVQEMTGASSPVFREDAPSERVHKEESAASLEYEESVLREDDAEAISENERVPVMYPIGQMHGTYILAQNERGLYIIDQHAAQERIKYEYYREKVGEIEQEVQEMLVPLTFHYSKNDMLIIEEHKEILTKVGVFLEPFGSGSYIVRSHPQWFPKGEEAELIEEIIEQVLVEKRVDIKKLREEAAIMMSCKGSIKANRHLRNDEIKALLDELRQTKDPFTCPHGRPIIIHHSTYEMEKMFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: QCR8_EQUAR
Sequence: QKVAVRLKEVVYTLSPHQQN
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 8, Complex III subunit 8, Complex III subunit VII, Ubiquinol-cytochrome c reductase complex 9.5 kDa protein, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C.
What is the protein family that this protein belongs to?
Belongs to the UQCRQ/QCR8 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RL1_ACIC5
Sequence: MSKKVSKNVAKARAAVEPRPYTLQDAVPLLQQVKFAKFDETVDLTMRLGVDPRHADQMVRGTVVLPHGLGKTKKVAVITTGDRQKEAEAAGAEIVGGEELVEKIQKESWTDFDALIATPDMMRSVGRLGKVLGPRGLMPNPKTGTVTNDVAAAVKEIKAGKIEYRTDKTALVHVPVGKLSFPAEKLIDNAMTVITSVVRAKPSAAKGKYIKGITLSSTMGPGIPLDGSVADAAAKA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ENTP7_MOUSE
Sequence: MARISFSYLCPASWYFTVPTVSPFLRQRVAFLGLFFIPCVLLLLLIMDLRHWATSLPRDRQYERYLARVGDLEATNTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHRETPLYILCTAGMRLLPERQQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDSDTSVDSAAGRRRTVGILDMGGASLQIAYEVPTSASDLPPKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGLTDMVKRNNQVLHFRGKGDWASCRTLLSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSEFFYCTEDVLRIGGHYHGPTFAKAAQDYCGMAWPVLAQRFKNGLFSSHADEHRLKYQCFKSAWMYEVLHEGFHFPYDYPNLQTAQLVYDREVQWTLGAILYKTRFLPLRDLRQGQGGVRPAHGSWLRLSFVYNHYLFFACTLVVLLAIVLYLLRIHRIHRRQTRASAPLDLLWIEQVVPMIGVQVGP
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner.  Preferentially hydrolyzes nucleoside 5'-triphosphates, with substrate preference for UTP > GTP > CTP.  Hydrolyzes nucleoside diphosphates only to a minor extent (By similarity).  In contrast to its human ortholog is able to hydrolyze ATP.  In the epithelial cells of small intestine controls luminal ATP levels, therefore regulating Th17-cell development (PubMed:23241884).
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 7, NTPDase 7, Lysosomal apyrase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: DCTA_PSEPK
Sequence: MTTRQPLYKSLYVQVLVAITIGILLGHYYPETGVALKPLGDGFVKLIKMVIAPIIFCTVVSGIAGMQSMKSVGKTGGYALLYFEIVSTIALIIGLVVVNVVKPGAGMHIDVSTLNASSVAAYAAAGAQQTTVGFLLNVIPNTVVGAFANGDILQVLMFSVLFGFALHRLGSYGKPVLDMIDRFAHVMFNIINMIMKLAPIGAFGAMAFTIGQYGVGSLVQLGYLMACFYITCLLFVLVVLGGICRAHGFSVIKLIRYIREELLIVLGTSSSESALPRMLAKMERLGAKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATDTTMDITHQITLLLVLLVASKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNAVATVVVAKWVKEMDNDKLASELDSGGAPLIDTRPTDDLGVAEGPAR
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KAX13_HOTTA
Sequence: QFTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ
What is the function of this protein?
Blocks selectively the high conductance calcium-activated (maxi-K) potassium channels (KCa1. 1/KCNMA1).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 1.3, Iberiotoxin, IbTx.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NRDR_DEHMC
Sequence: MNCPYCSHPDSKVIDSRDVDDGVRRRRECVVCGQRFTTYERFQPAGLFVVKKDQRREEFNKEKLLSGLRRACEKRPLPAGAVDKVAGDIEAELYNMGKAEIPSTLLGDMVMERLKMLDNIAYVRFASVYREFTDITQLKKVVDNLVNGQDEGIYKGQLSLLPEDKAVPKTRYQRR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SAPN1_PINCO
Sequence: MSPVSVISLPSDLCLPTSFIDRSGRELNPLHITIPNVAMRRQGKLMTRASMSVNLRTAVSDDAVIRRRGDFHSNLWDDDFIQSLSSHYGEPSYRERAERLIGEVKNSFNSVSNEDGESITPLDDLIQRLWMVDSVERLGIDRHFKKEIKSALDHVYSYWSEKGIGCGRESVVTDLNSTALGLRTLRLHGYDVSAEVLNHFKNQSGQFACTLKQTEDQIRTVLNLYRASLIAFPGEKVMDEAETFSAKYLKDALQKIPVSSLSREIGDVLEYGWHTYLPRLEARNYIDVFGQDTENSKSYMKTEKLLELAKLEFNIFHALQKRELEYLVRWWKGSGSPQMTFCRHRHVEYYTLASCIAFEPQHSGFRLGFAKACHIITVLDDMYDTFGTLDELELFTSAIKRWDPSATECLPEYMKGVYMIVYNTVNEMSQEADKAQGRDTLNYCRQAWEEYIDAYMQEAKWIASGEVPTFEEYYENGKVSSGHRVSALQPILTTDIPFPEHVLKEVDIPSKLNDLASAILRLRGDTRCYQADRARGEEASCISCYMKDNPGTTEEDALNHINAMISDVIKGLNWELLKPNSSVPISAKKHAFDISRAFHYGYKYRDGYSVASIETKSLVKRTVIDPVTL
What is the function of this protein?
Monoterpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens (PubMed:23679205).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to (-)-alpha-pinene and, to a lower extent, to (-)-beta-pinene (PubMed:23679205).
What are the official names of this protein?
(-)-alpha pinene synthase 1, chloroplastic, (-)-beta pinene synthase 1, chloroplastic, Terpene synthase (-)alphapin1, PcTPS-(-)alphapin1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PHDI_NOCSK
Sequence: MNSSNTGAPEAAQAATLEAFDRRAAEQYLRGQWIAEEHLMRAIGGPRPAGIPYRWEWKSVEVALDEATIALGPVDTARRHLTFVNPGLMDRGSATTHTISAGFQLVKPGEVCWSHRHTMSAVRFVTKGHPDAFTAVDGERLPMEDFDLLITPRFSWHDHHNSGDADVVWLDGLDIGLLQSLGAVFYEPYGDDSQNVRPSSSEGIGTRSHWLRPTWERGRESRLPIRYPWKEVNARLDVYDLDAGTPYDGLALRYANPVTGGPTMATMDCWVQRLAPGFDGKSHRRSSSAITYVISGSGTMVTEDETITFNRGDVISLPNWTNFRWTNDSEIEPVLLFSMHDIPALEAFGLLYEEPEAILNATPAPINPTPSLNPIYRPGAFYDQDEL
What is the function of this protein?
Dioxygenase involved in phenanthrene catabolism by mediating cleavage of 1-hydroxy-2-naphthoate.
What are the official names of this protein?
1-hydroxy-2-naphthoate 1,2-dioxygenasee, 1-hydroxy-2-naphthoate-degrading enzyme, 1-hydroxy-2-naphthoic acid dioxygenase.
Protein: METAA_RHIE6
Sequence: MPIKIPDTLPAFETLVQEGVRVMTETMAIRQDIRPLQIGLLNLMPNKIKTELQMARLVGASPLQVELSLIRIGGHKAKNTSEDHLLAFYQTWEEVKQRKFDGFIITGAPIELLPYEDVTYWKEMQEILDWTETNVHSTMNVCWGAMAAIYHFHGVPKYELKEKAFGVYRHRNLKPSSIYLNGFSDNFEVPVSRWTEVRRADIEKSDSLEILMESSEMGVCLVHEKRGRRLYMFNHVEYDSTSLSDEYFRDVDAGVPIKMPHNYFPHNDPALAPQNRWRSHAHLLFGNWINEIYQTTPYDVEEIGMDL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHAD1_AMAPH
Sequence: MSDINTTCLPAWLATCPCTGDDVNPTLTCGESLC
What is the function of this protein?
Toxin that belongs to the bicyclic heptapeptides called phallotoxins (PubMed:27978833).  Although structurally related to amatoxins, phallotoxins have a different mode of action, which is the stabilization of F-actin (PubMed:6452160).  Phallotoxins are poisonous when administered parenterally, but not orally because of poor absorption (PubMed:27978833).
What are the official names of this protein?
Phalloidin proprotein.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: RRF_BACVZ
Sequence: MSNEVLTQTKERMEKAVAAYSRELASVRAGRANPSLLDKVTVEYYGAQTPLNQLSSINVPEARMLVVTPYDKTAIGDIEKAILKADLGVTPTSDGTIIRIAIPALTEERRKELVKVVKKYAEEAKVAVRNVRRDSNDDLKKLEKNGDITEDELRASSEDVQKLTDEYVSKIDSVTKDKEKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPPS_KLULA
Sequence: MSDNRAQFLEVFPSLVQELRDILAGYGMPEEAIEWYEKSLNYNTPGGKLNRGLSVVDTYALLKGYKSVSELSAEEYKKVAILGWCIELLQAYFLVADDMMDQSITRRGQPCWYKVENVGDIAINDAFMLEGAIYCLLKKHFRTEPYYVDLLELFHDVTFQTELGQLLDLITAPEDKVDLSKFSLEKHSFIVIFKTAYYSFYLAVALAMFAAGITDSKDLKQASDVLIPLGEYFQIQDDFLDCFGKPEDIGKIGTDIQDNKCSWVINVALKNATKEQRDILDENYGRKDSEKEQKCRAVFNELNIQDIYHKYEEETASNLREKIANIDESRGFKAEVLTLFLNKIYHRKK
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
What are the official names of this protein?
Farnesyl pyrophosphate synthase, FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_STAAT
Sequence: MKVLNLGSKKQASFYVACELYKEMAFNQHCKLGLATGGTMTDLYEQLVKLLNKNQLNVDNVSTFNLDEYVGLTASHPQSYHYYMDDMLFKQYPYFNRKNIHIPNGDADDMNAEASKYNDVLEQQGQRDIQILGIGENGHIGFNEPGTPFDSVTHIVDLTESTIKANSRYFKNEDDVPKQAISMGLANILQAKRIILLAFGEKKRAAITHLLNQEISVDVPATLLHKHPNVEIYLDDEACPKNVAKIHVDEMD
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: CLPP_DESVM
Sequence: MPVPIVIETSGRSERAYDIYSRLLKDRIILLGTPIDDQVASLICAQLLFLESENPEKEIYLYINSPGGSVTAGMAIYDTMQYITSPVATLCLGQAASMGALLLAAGAPGMRHALPNSRIMIHQPSGGFHGQASDIDIHAREVLRMKANLNEIMARHTGQPVERVADDTERDYFMGPAEAKEYGIIDSILTSRRDATQNQAK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_PORG3
Sequence: MYVIVDIQGQQMKVEQGRRLFVHHIKDVESGASVEFDKVLLVDNNGAIAVGSPLVEGAKVVCEVLTPLVKGDKVLIFHKKRRKGYRKLNGHRQQFTEILVKEVVA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: THIM_PYRAB
Sequence: MNFIVEALNEVRKRKPLVHNITNFVVMNTTANALLALGASPVMAHAEEELEEMIGLADAVVINIGTLDSWWRKSMIKAVEIANEMKKPIVLDPVGAGATKLRTKVALEILDRGVTVLKGNFGEISSLLGEFGKTRGVDSSEYDEEKAKVLALSAAKEFNTTVAVTGAVDYVSDGGKVFAIYNGHKLLERVTGTGCIVTAITGAFVAVTEPLRAAISSLVVFGIAAEKAYEEAKYPGSFHVKLYDWLYRIDGEVIRKYAKVREVGV
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: O16C_CONVX
Sequence: MKLTCVLIITVLFLTASQLITADYSRDQRQYRAVRLGDEMRNFKGARDCGGQGKGCYTQPCCPGLRCRGGGTGGGVCQP
What are the official names of this protein?
Conotoxin 12.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SNRPA_HUMAN
Sequence: MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1 snRNP is the first snRNP to interact with pre-mRNA.  This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP.  SNRPA binds stem loop II of U1 snRNA.  In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.  May bind preferentially to the 5'-UGCAC-3' motif on RNAs.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein A, U1 snRNP A, U1-A, U1A.
What is the protein family that this protein belongs to?
Belongs to the RRM U1 A/B'' family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPOD1_DICDI
Sequence: MKRSIVTGGGNNDKKFKAQPPPKNNYRGGGDDEEDDEFEEDDDEDEGDEFGEEEDEDDIDVENIIASDSMDIDIQDDGSQQLFLWSRKPVQDLVPHKKPLIFQQLEVDYTEIKEPVPGMPGPKVGPLPAIRLFGVTKEGNSVLCKVHGFLPYFFISCPPGFTEADCKSLKHDLNESMKMSSNQSNEKDIENIVVSIDIEKKKSIMGYNPNPLSDFIRITLILPKFVTRCREIFESGRHHFTIPGQPFRQYQTYESNILFALRFLIDKGITGCSWIELPANTYKLSETPVSTCQIEVDTSLETIISLSDDDSPAPYRILSFDIECAGRKGVFPEPEKDPVIQISNIVKNNGDAEPFIKNIFTLKGCSSIVGAHVIPHKREEDLLREWRKFVIKVDPDVIIGYNIVNFDIPYLISRARQLKIPEFALLGRIKTTISKIKSTRFSSSNLGTRESKEISMPGRTQFDLMQAIQRDHKLTSYSLNNVSAHFLKEQKEDVHFSIISDLQNGTDDDRRRLAVYCIKDAVLPMRLLDKLMILINYTEMARVTGVPLSYLLGRGEGIKVLSQLYRKAMVENFLIPTYKVTGKGEKFQGAIVIEPTPGFYDTPIATLDFTSLYPSIMMAHNLCYSTLLSAEEAKKLPPEIYTTTPFGDHFIKSDTKKGLLPRILEELLSARKKAKDELKNEKDPFKRAVLDGRQLALKISANSVYGFTGARVGKLPCLEISRSVTSFGREMLDKTKKIVEERYTIANGYKHDAVIIYGDTDSVMVKFGVKTVAEAMEMGRDAAKFVTTTFIRPINLDFEKVYYPYLLMAKKKYAGLYWTKPDIHDRMDVKGLEMVRRDTCLLVRNVVSTILKKILIEKDLKSAEEYTKSVISDLLQNRLDLSMLVITKALSKTQYKGKVIHNELARKMRARDPATAPNLGDRVPYVVIQGSKGAPIYEKAEDPLYALEHNILLDCQYYLDKQLKAPLIRIFKPIMSNPDLIFHGEHTRTIAQSTLSDNNKGFFGTLKKKKVCMNCPKELTDTESTTCINCQHKEASLYQTSLEKVTSLETKFSEAWTQCQRCSGSLHQPVLCSNRDCPIFYMRTKVQLDLIEAKKTLNRFNVEW
What is the function of this protein?
Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
What are the official names of this protein?
DNA polymerase delta catalytic subunit, DNA polymerase III.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SOX12_XENLA
Sequence: MVQNKTTGSCPKPTEVAPGGPSWCKTSNGHIKRPMNAFMVWSQIERRKLMSLCPNMHNADISRSLGQRWKLLQDTDKIPYVREAERLRLKHMADYPNYKYRPRRRSRTQESKTRARLPRSTATCQSVPSPCLSQMDTGSSMQWGETCPAWGGDQVGQSVETQIRESSARSPEVPTHTKTVPSSPQSAEEHEGLEGGSLVIPVDKEVPPHSGSHFEFPDHCTPEVMEMISGSGLLESVPDLVFSY
What is the function of this protein?
Transcription factor that binds to the sequence 5'-AACAAT-3' (PubMed:12890561).  Acts as a transcriptional activator (By similarity).
What are the official names of this protein?
Transcription factor Sox-12, Sox-K1 protein, XSox-K1, Transcription factor Sox-33, xSox-33, xSox33.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUC_BRUA4
Sequence: MSAPRTLYDKIWDDHVVDQQEDGTCLLYIDRHLVHEVTSPQAFEGLRMAGRKVRHPEKTLAVVDHNVPTSPDRINGIKNEESRIQVEALAKNAADFNVEYYSERDRRQGVVHIVGPEQGFTLPGMTIVCGDSHTSTHGAFGSLAHGIGTSEVEHVLATQTLIQKKAKNMLVRVEGELAPGVTAKDITLAIIGEIGTAGGTGYVIEYAGSAIRSLSMEGRMTVCNMSIEGGARAGLIAPDETTFAYVQDKPRAPKGEALEQAISYWKTLHSDEGAHFDKIVELDAAKISPVVSWGSSPEDVVFVTDIVPNPDEIKDETKRASKWRALDYMGLKPGTKMTDIKIDRVFIGSCTNGRIEDLRDAARMAAGKKVAAGVNAMIVPGSGLVKEQAEAEGLDKIFIEAGFDWREPGCSMCLAMNDDRLKPGERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAAIAGHFVDIREWN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RL7_VIBC3
Sequence: MSITNEQILDAIAEMSVMQVVELISAMEEKFGVSAAAAVVSGPAAAAAVEEQTEFNVILAAAGANKVAVIKAVRGATGLGLKEAKALVDGAPASVKEAVSKEEAEALKKELEEAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ZRAP_DESVH
Sequence: MNSKRIALGIIALATVVSLGTAANNAFARGHGNYHGQGQMMGQAYEALTPEKQAKFDSLIDAFNTKVTPLRDKLWAKHTELNALSSNPNTKPEDIRKLTDEITALRTQYRTEAANLDASMQKEVGIKTHFATMGHRGMGGMGGGCGMMGGKGGMGSGMMQMHDGEGPHRGQNM
What are the official names of this protein?
Zinc resistance-associated protein homolog.
What is the protein family that this protein belongs to?
Belongs to the ZraP family.
Protein: GLRX_NEIMA
Sequence: MQTVTMYTGPFCPYCTMAKRLLHAAGVGHIDEIRVDASPEAFAEMQQLSGQRSVPQIFIGETHVGGFTDLYRLQQEGGLDGLLNP
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins (By similarity).
What are the official names of this protein?
Glutaredoxin.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCL8_MOUSE
Sequence: MKIYAVLLCLLLIAVPVSPEKLTGPDKAPVTCCFHVLKLKIPLRVLKSYERINNIQCPMEAVVFQTKQGMSLCVDPTQKWVSEYMEILDQKSQILQP
What is the function of this protein?
Chemotactic factor that attracts monocytes.  This protein can bind heparin (By similarity).
What are the official names of this protein?
C-C motif chemokine 8, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TREA_SALEP
Sequence: MIPPEIRRSVLLQKAIKLALAGTLLTFASFSATAADPSSDTETPQPPDILLGPLFNDVQNAKLFPDQKTFADAIPNSDPLMILADYRMQRNQSGFDLRHFVDVNFTLPKAGEKYVPPAGQSLREHIDGLWPVLTRSTKNVEKWDSLLPLPESYVVPGGRFREIYYWDSYFTMLGLAESGHWDKVADMVANFGYEIDAWGHIPNGNRTYYLSRSQPPFFAFMVELLAQHEGDDALKEYLPQLQKEYAYWMEGVETLQPGQQNQRVVKLEDGSVLNRYWDDRDTPRPESWVEDIATVKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLSTIRTTTIVPVDLNALLYQLEKTLARASAAAGDRAKASHYDALANARQKAIEMHLWNNKEGWYADYDLKNNKIRDQLTAAALFPLYVNAAAKDRAAKVAAAAQAHLLQPGGLATTSVKSGQQWDAPNGWAPLQWVAAEGLQNYGQDDVAMEVTWRFLTNVQHTYDREKKLVEKYDVSSTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPQEKPCDSVPSTRPASLSATPTKTPSAATQ
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.