PharMolix/UniProtQA huggingface dataset:
Protein: CH10_RUEPO
Sequence: MALKPLHDRVLVRRTESEEKTAGGLIIPDSAKEKPSEGVVVACGEGARKDSGELIAMAVKSGDRVLFGKWSGTEVTVDGEELLMMKESDIMGIIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_PSEMY
Sequence: MNPVIKQFKFGQSTVTLETGRIARQASGAVLVTVDNDVTVLVTVVGAKTADPSKGFFPLSVHYQEKTYAAGKIPGGFFKREGRPSEKETLTSRLIDRPIRPLFPEGFMNEVQVVCTVVSTSKKTDPDIASMIGTSAALAVSGIPFNGPIGAARVAFHPDTGYLLNPNYEQLKASSLDMVVAGTETAVLMVESEADELTEDQMLGAVLFAHQEFQAVIQAVKEFAAEAGKPTWNWQAPAANTPLLDAIRSQFGEAISQAYTITIKQDRYNRLDELREQVIAALAGEGEGKFAADEVKAAFGEIEYRTVRQNIVDGKPRIDGRDTRTVRPLKIEVGVLDKTHGSALFTRGETQALVVATLGTARDAQLLDTLEGEKKDPFMLHYNFPPFSVGECGRMGGAGRREIGHGRLARRGVAAMLPKDDEFPYTIRVVSEITESNGSSSMASVCGASLALMDAGVPMKAPVAGIAMGLVLEGEKFAVLTDILGDEDHLGDMDFKVAGTAKGVTALQMDIKIQGITEEIMEQALEQALEARLNILGQMNQVISQSRTELSANAPTMLAMKIDQDKIRDVIGKGGATIRAICEETKASIDIEDDGSIKIFGETKDAAEAAKQRVLAITAEAEIGKIYVGKVERIVDFGAFVNILPGKDGLVHISMLSDQRVEKVTDVLKEGQEVKVLVLDVDNRGRIKLSIKDVAAAEASGV
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHK5_SCHPO
Sequence: MSVYQTYKGLPAGWVAQWDPTYQAYFYINETFEGAQPQWEPPIPGLHIPPPPGTTTVVYQKDVPRSSDGSRSMTAGLGGFMVGALAGSVLRGHRAYYAPPPPRGPLFGPRIGGGHHGPLHGPHGGFGGRGGGRMGGRGGRGRR
What are the official names of this protein?
WW domain-containing protein C660.05.
Protein: RK33_AETGR
Sequence: MAKGKDVRVTIILECTNCVRNDIKKESPGISRYITQKNRHNTPSRLELRKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ISPT_STRPN
Sequence: MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: FLGI_ALBFT
Sequence: MQFFNTLHPTRPHWLLAALCLIASLLGAGTAQASRIKEVAAVEGVRSNQLTGFGLVVGLDGTGDQTTQMPYTAQGLTNYLQQLGITLPEAQVSKLQLKNVAAVLVTAALPAFARPGQAIDVNVSSMGNAKSLKGGTLITTPLKGADGEVYALAQGSLVVAGAGAAAGGSKVQINHLSAGRIPGGAQVERIVPTPLLEGASITLGLQASDFQTARRVAEAINRRFGAHSARALDGRTIDVTAPSESNARVSFIAEMEELQLESSIPSAKVVINSRTGSIVMNQAVTLGECAIAHGNLSVSISTTPVISQPNPLSTGGKTVVAEKSNIQIRQEPGMLIQLPKSTQLSDVVRALNALGATPQDLLAILQAIKAAGALNAELEVI
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: PER_DROTE
Sequence: EGSGGSGSSGNFTTASNIHMSSVTNTSIAGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGNGSASSNYRGGGVAIQPVTLTESLLNK
What is the function of this protein?
Essential for biological clock functions.  Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms.  Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system.  The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex.  Light induces the degradation of TIM, which promotes elimination of PER.  Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop.  Behaves as a negative element in circadian transcriptional loop.  Does not appear to bind DNA, suggesting indirect transcriptional inhibition (By similarity).
What are the official names of this protein?
Period circadian protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Nuclear at specific periods of the day. First accumulates in the perinuclear region about one hour before translocation into the nucleus. Interaction with Tim is required for nuclear localization (By similarity).
Protein: Y261_RICBR
Sequence: MYNSTSFTIIKHYYILGIKMPKKCTQVFDEFLQVIHQNIVGEDKAIIDILNTLGVEQANDLISAAFLKHFKFMHLEHWQRYPLNIVSTDIIDEQGENVIHKCVRYDKIDFLKHIPSIGFNLGIPNKDGDTPLHLAYKKLIYAQSYPAFTKAKNTLLNIVNFKNKDEISSQFIGVLINLEYIFKPIIDFNYNVATFNHFMHHKPSAPILSDINTPINNFKPLLPRITLLRDINETSSFRDLAPPGHKRKTNSIEYNNTKKHKTISNDSHHNLYSSIENKRLDNDLNSTSKTTTTTSYNELDKLLIAFSNTNNASINNVLDTDEVALIGNKFI
What are the official names of this protein?
Putative ankyrin repeat protein RBE_0261.
Protein: ARLY_PROM9
Sequence: MAKVWSKRFDNTLNPFIEKFNASISFDKKLILEDLECSIAHAKMLGKTKVLSSSETLLIINGLEKIKVEYLEDKFSPSLPSEDIHYCIEEKLISLIGETGKKLHTGRSRNDQVGTDLRLWLRKEIDNLEILITDLQKSFLNLAKSNIHTLIPGYTHMQRAQPLSLAHHLLAYLEMFQRDRERFQEVRSRVNISPLGAAALAGTKIKIDRNFTAEELGFDKIYKNSIDAVSDRDFCIEFVSASALAMSHLSKISEEIILWVTDEFSFAKLTDKCATGSSLMPQKKNPDVPELIRGKTGRVYGNLQALLTMVKGVPLAYNKDFQEDKEPIFDTAETISSSIKAMTILITEGIEFNIKNLSESVQNDFSNATDLADYLVCKQVPFRTAYHVVGEIVKYCLEREILFKDLKISEIKKFHPEFDEDVFVDLEPFNVVKSRTSEGGTGFTQVEKEVNNWQKKLLL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_BURCM
Sequence: MPQRHPQPAHPADGIYFGLMSGTSMDGVDGVAVRFETGHAPVVLAEAFVGFAQSLRDALFALQQPGDDEIDRESLAANALVARYAVCCHELQRTAGLSRDEIRAIGVHGQTVRHRPERGYTRQLNNPALLAELTQVDVIADFRSRDVAAGGHGAPLAPAFHATVFGAPGETRVVCNLGGISNITILPGEGGDVRGFDCGPANALLDEWATRHLGKPYDDGGKFAARGTVHAPLLDALLDEPYFAAAPPKSTGRDLFNPGWLDAKLAAFVQVAPQDVQATLTALTAVSVAREVATHASGCKALFVCGGGARNPVLLDALRHALHEAGVLASVDTTAALGVPPQQVEALAFAWLAYRFTGREPGNLATVTGAAGNRVLGALYPR
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: YBJL_SALSV
Sequence: MNINVADLLNGNYILLLFVVLALGLCLGKLRLGSVQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGIASTQLSSALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMITFQFSNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGISNGLGAVGGQMLIAGLVVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIVIIWPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS13_THET8
Sequence: MARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAPRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome structure it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the top of the two subunits; these bridges are in contact with the A site and P site tRNAs respectively and are implicated in movement during ribosome translocation.  Separately contacts the tRNAs in the A and P sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PFKA_KLEP7
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFREEHIRAVAIENMKKRGLDALVVIGGDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGDLTLAAAIAGGCEFIMVPEVEYTRDDLVAEIKAGIAKGKKHAIVAITEHMCDVDELASYIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIELLLQGHGGRCVGIQNEKLVHHDIIDAIENMKRPFKNDWLDCAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP1_PROMM
Sequence: MIDSYCYHPIHNRWQGIRPVSSPGILPTVVEQSGRGERAFDIYSRLLRERIIFLGTGVDDQVADALVAQMLFLEAEDPEKDIQIYINSPGGSVTAGLAIYDTMQQVAPDVVTICYGLAASMGAFLLCGGTKGKRLALPNARIMIHQPLGGAQGQAVDIEIQAKEILFLKETLNGLLAEHTGQPLNKIAEDTDRDHFLSPAKAVEYGLIDRVVDSLTGGGIVKEG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT221_ASPTN
Sequence: MAFTPSSPPSPAADASQRPSRYPGEDTTPTSRREILGWYAYGIAAEVFAVCGVGSFLPLTLEQLARERGVLKSSHLPCVGPDAPTSSLANGTAPALLRRDGADNDQCVVGLLGLEINTASFAMYTFSLAVLVQALTLISFSALADYENNRKTLLLAFGFIGSATSMLFVFVAPPVFTFGAILVIIGVTCLGSSFVVLNSFLPVLVANDPSIQGASKEADEELHTLNENGQFEPRDSFSERNPEFESQYTPGIGLGSKPSTNATSPELQLSTRISSKGVGLGYCAAVLVQILSIGLLFALSKTSLPKVSGTLPLRFVLLLVGIWWFSFTMVTRRWLRNRPGPPLSTTTTGGHTNKWRVWLRLVGFAWKSLWKTVKIAVQLREVRVFLVAWFLLSDAIATVSGTAILFARTELKMSTTLVGCLSITATLSGMTGAFLWPVVSRRFKLKSSHTIMLCIALFEIIPLYGMLAYIPLFKKWGVIGLQQPWEIFPLAIVHGIVSGGLSSYCRSFFGLLIPPGSEAAFYALYAATDKGSSVIGPAIVGMLIDATGQVRSGFFFIAILIVLPIPLVWMVNAEKGRMEGVAMAERMAKGQESETGEPGEEAEGLLARGA
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22-1.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: GGR_THEAC
Sequence: METYDVLVVGGGPGGSTAARYAAKYGLKTLMIEKRPEIGSPVRCGEGLSKGILNEADIKADRSFIANEVKGARIYGPSEKRPIILQSEKAGNEVGYVLERDKFDKHLAALAAKAGADVWVKSPALGVIKENGKVAGAKIRHNNEIVDVRAKMVIAADGFESEFGRWAGLKSVILARNDIISALQYRMINVDVDPDYTDFYLGSIAPAGYIWVFPKGEGMANVGIGSSINWIHNRFELKNYLDRFIENHPGLKKGQDIQLVTGGVSVSKVKMPITMPGLMLVGDAARLIDPITGGGIANAIVSGMYAAQVTKEAIESNDYSPQMMQKYEKLIKERFERKHLRNWVAKEKLAMLSDDTLDKLVDIVSEQVLTTISVEAILKAIAEKYPEVVKELEDLI
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.  Can use both NADH and NADPH as electron donors.  Also catalyzes the reduction of the naturally occurring 2,3-di-O-geranylgeranylglyceryl phosphate derivatives such as 2,3-di-O-phytyl-sn-glyceryl phosphate (DPHGP), 3-O-(2,3-di-O-phytyl-sn-glycero-phospho)-sn-glycerol (DPHGPG) and 2,3-di-O-phytyl-sn-glycero-phosphoethanolamine (DPHGPE).  Is not active toward 2,3-di-O-geranylgeranylglycerol.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PUR5_ALISL
Sequence: MSDNKTSLSYKDAGVDIDAGNALVDRIKGVVKRTRRPEVMGGIGGFGALCELPTKYKQPVLVSGTDGVGTKLRLALDLNKHDTIGIDLVAMCVNDLIVQGGEPLFFLDYYATGKLDIDVAAQVVTGIGEGCIQAGCALIGGETAEMPGMYEGEDYDVAGFCVGVVEKEDIINGTKVAAGDALIAVGSSGPHSNGYSLIRKILEVSNADLTEELNGRTIADHLIEPTKIYIKSALKMIAEHDIHAISHITGGGFWENIPRVLPEGTKAVVDGKSWEWPAIFNWLQEKGNVDTYEMYRTFNCGVGLIVALPKEQAEQAVALLNAEGENAWVIGKVAAAEQGEEQVEIR
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_STRP4
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVNDAVAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NUON2_OPITP
Sequence: MTSFVSFLPELVLLAGALALFVVTLGQNNVRLARILSVATASGVLVAALATVNHSAVLFSGAYRVDAFSQLLKIAIAFGYLCVGILSGQLRDIRGEAKPEYFLFLALSMTGLLALVSSIDVITLIIALELSSFPLYLMVAMRREREGQRVQMESAIKYIMFGIAANGVMFFGFGYLYGLTGSTSLPVILEKLPPLLSSPLAVTGLALTLAGFLYKLAVFPFHFWTPDVYQGSSNETASLIASLPKLGAVAVLVRFVSLAAPGHETLATLLTCLAIASMVYGNLIALVQTDLKRLLGFSGIAHAGYVMVGFVAMDNFGFASALYYIAGYMLMVLACFVVVCQVSRDGANVAITELAGLHKRSPLLAVTLIVGVFALAGVPPFVGFMAKLNLLTSAWQAGHTALVVLTVINSAIAIYYYLQIVRAAFFAESDAQPAPIALTPSMSALCVLLIVAITLLGVAPAFTIDAITNSLATISTVSS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 2, NADH dehydrogenase I subunit N 2, NDH-1 subunit N 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPC_RIPO1
Sequence: MQIRRRSPNPPVEVDTLRYQVKVPDGEPRHILEEIVWHKEKEVDRLRESLPLLELRKQVQHLPPPQDFLGAITQGKTQPALIAEVKKASPSKGVIREDFDPVAIAQAYVKGGASCLSVLTDAKFFQGSFENLALVRQSVDLPLLCKEFILYPYQIYLARTKGADAVLLIAAILSDRDLSYFLKIIQTLGMTALIEVHSLTELDRVLAIEGVSLIGINNRNLETFEVDLKTTSQLLAARRDKIQALGIKIISESGLHTPDDLQFVQQAGSDGVLIGESLVKQPDPTQAIANLFG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: LAN43_PROMM
Sequence: MSEEQLKAFIAKVQADTSLQEQLKAEGADVVAIAKAAGFTITTEDLNSHRQNLTDDELEGVAGGTASGGCDTSMFCY
What is the function of this protein?
Lanthionine-containing peptide (lantipeptide) with unknown function (Probable).  Does not show antibiotic activity against Lactococcus lactis 117 and Bacillus subtilis 6633 bacteria (By similarity).  Organisms that produce this peptide live in oligotrophic environments at very dilute concentrations, suggesting this peptide is not secreted to influence other bacteria (Probable).
What are the official names of this protein?
Lantipeptide prochlorosin 4.3, Lantipeptide Pcn4.3.
What are the subcellular locations of this protein?
Secreted.
Protein: NU2C_SYNP2
Sequence: MDFSSTVASQLYTGAILPESIVILTLIVVLVGDLIVGRARSGWIPYAAIAGLLGSVFALYLGWDNPHPVAFLGAFNSDNLSILFRGIIVLSTAFTIMMSVRYVERSGTALSEFICILLTATLGGMFLSGANELVMIFVSLEMLSISSYLLTGYMKRDPRSNEAALKYLLIGAASSAIFLYGVSLLYGLSGGKTILSEIALGFTDPQGGQSLALAIALVFAIAGIAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLVTVFNPVSEEWHFIFTALAILSMVLGNVVALAQTSMKRMLAYSSIAQAGFVMIGLVAGTDAGYSSVIFYLLVYLFMNLGAFTCVILFSLRTGTDQIAEYAGLYQKDPLLTLGLSVCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYGLVLLGLITSVISIYYYIRVIKMMVVKEPQEMSDSVRNYPAVTWTAVGMKPLQVGLVLSVIITSLAGILSNPLFVIADQSVTSTPMLQVANHPTEQVVAQVDSELVGVAIADH
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: VIOB_ECOLX
Sequence: MAYLDEIQLKEMGFKSVGENVKISDKASFYGCDNISIGNNVRIDDFCVFSAGEGGIDIHDYIHIAVYSSIIGKGKVTISDYANISSRVSIYSSNEYYSGNYMSNPVVPSEYTNIHSGTVFIGKHVIIGCGSIVLPDVILHEGAAIGALSVVKEDCEAFTVNVGIPAKPISERSKKLLELESVFKPSAIGDNL
What is the function of this protein?
Catalyzes the conversion of dTDP-4-amino-4,6-dideoxy-D-glucose (dTDP-D-Qui4N) to dTDP-4-acetamido-4,6-dideoxy-D-glucose (dTDP-D-Qui4NAc).
What are the official names of this protein?
dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: ACKA_EMENI
Sequence: MPRKSILSVNAGSSSVKITFYSYTKTPSVIATAQVSGITAPPATFKYSVGSKQKKEELKEKISSGPDAFKLLLHRCFTDSDLKDVASADDLAYICHRVVHGGDFESPVVINEETYHQLEDLEDLAPLHNFAALEIVRLCKKELPNVQSITFFDSSFHKSLPPYVKTYPIDQETARRNKLRKYGFHGISYSFILRSVAEYLNKPVEKTSLIALHIGSGASVCAIKDGKSIDTSMGLTPLAGLPGATRSGDIDPSLVFHYTNEAGKLSPASTKEMHISTAEEILNKKSGWKVLTGTTDFSQIAVEDPPSEQHKLAFDILVDRIVGYIGNYYVKLDGQVEGIVFAGGIGEKSALLRKAVIEQTRCLGFAVDPEKNQHGPGDDETVVDITASGRSDVKRVFICQTDEQFEMAYNCTKTQGLDKQ
What are the official names of this protein?
Probable acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
Protein: SL9A5_HUMAN
Sequence: MLRAALSLLALPLAGAAEEPTQKPESPGEPPPGLELFRWQWHEVEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVIFMLLGISAVDSSKWAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRSEHHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFVDQGGHVLSSTGLTLPSMPSRNSVAETSVTNLLRESGSGACLDLQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLESFKSTKHNICFTKSKPRPRKTGRRKKDGVANAEATNGKHRGLGFQDTAAVILTVESEEEEEESDSSETEKEDDEGIIFVARATSEVLQEGKVSGSLEVCPSPRIIPPSPTCAEKELPWKSGQGDLAVYVSSETTKIVPVDMQTGWNQSISSLESLASPPCNQAPILTCLPPHPRGTEEPQVPLHLPSDPRSSFAFPPSLAKAGRSRSESSADLPQQQELQPLMGHKDHTHLSPGTATSHWCIQFNRGSRL
What is the function of this protein?
Plasma membrane Na(+)/H(+) antiporter.  Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, thus regulating intracellular pH homeostasis, in particular in neural tissues (PubMed:9933641, PubMed:10692428, PubMed:19276089, PubMed:24936055).  Acts as a negative regulator of dendritic spine growth (PubMed:21551074).  Plays a role in postsynaptic remodeling and signaling (PubMed:24006492, PubMed:21551074).  Can also contribute to organellar pH regulation, with consequences for receptor tyrosine kinase trafficking (PubMed:24936055).
What are the official names of this protein?
Sodium/hydrogen exchanger 5, Na(+)/H(+) exchanger 5, NHE-5, Solute carrier family 9 member 5.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YP010_YEAST
Sequence: MRPAQLLLNTAKKTSGGYKIPVELTPLFLAVGVALCSGTYFTYKKLRTDETLRLTGNPELSSLDEVLAKDKD
What are the official names of this protein?
UPF0495 protein YPR010C-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0495 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Single-pass membrane protein.
Protein: CEP1_HHV8P
Sequence: MSLERALARLTGVPMSTHAPKTRESEEACPVYPHPVVPRLVLEVHRKNNALVGSNTPKMSVMGHLDIACLREHVKSRLSSPNFVGFTVVCLVEHEDMVTHIDLHPHVFQERVCLLRPTSPGITELCCLLSMLENCRDMSPTFLRSIICRARKTHERTPGMDAAFVMHGIETLTATAAFVYELSVDDHFRATPLVMFKLHKAIGDASTPMGGLMKPIYLESFKLESSGENEDDKQTCADPVNIFYCDTIFTKHLENNEVLKYLKMCTLFKPPIVSLFSK
What is the function of this protein?
Plays a critical role in cytoplasmic virus egress.  Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.
What are the official names of this protein?
Cytoplasmic envelopment protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 1 family.
What are the subcellular locations of this protein?
Virion. Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein: ACP_WIGBR
Sequence: MSTIEESVKSIIAEQLGVKKEEVTNNASFVDDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDFIKESKK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.