PharMolix/UniProtQA huggingface dataset:
Protein: NXT2_MOUSE
Sequence: MALAVNFKTYVDQACRAAEEFVNIYYETMDKRRHALVRLYLDKATLIWNGNVVTGLEALANFFEMLPSSEFQINMLDCQPVHEQATQCQTTVLVVTSGVVKFDGNKQHFFNQNFLLTAQSTPNSTVWKIASDCFRFQDWASI
What is the function of this protein?
Regulator of protein export for NES-containing proteins.  Also plays a role in mRNA nuclear export (By similarity).
What are the official names of this protein?
NTF2-related export protein 2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: EXPA6_ORYSJ
Sequence: MAPPLLLLLASLLLVAARRALGLGLGQWQPGHATFYGGGDASGTMGGACGYGNLYSQGYGTSTAALSTALFNRGLSCGSCYELRCAGDHRRSCLPGGATVTVTATNFCPPNYALPSDGGGWCNPPRRHFDLAEPAFLRIARHAAGIVPVSFRRVACARKGGVRFTVNGHAYFNLVLVTNVGGAGDVRSLAVKGSGSGSRVGGRWQPMSRNWGQNWQSNAYLDGKALSFRVTAGDGRSLTCADVAPAGWQFGQTFEGRQF
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
What are the official names of this protein?
Expansin-A6, Alpha-expansin-6, OsEXP6, OsEXPA6, OsaEXPa1.24.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: COAX_XANC8
Sequence: MSEWLFDLGNSRFKYAPLDGTRAGDVQAWAHGAEAMDTAALSALPSGKVAHVASVAAAGLTERVLASLRTRFEQVRVVRTAAACAGVRIAYADPSRFGVDRFLALLGARGDAPVLVAGVGTALTIDVLGADGQHHGGRIAASPTTMREALHARAVQLPPTGGAYAELANDTDDALTSGCDGAAVALIERSLQHAARTLGMPVCLLVHGGGAPPLLPLLPTAEFRAALVLDGLATWATHSAAP
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_CLOAB
Sequence: MIRVKIPATSANMGAGFDTLGMALKLYNEITIEETEGETEIKLLGGELDRNYRNNLTYISIIKVYEFFNKEFKGFKIDMSKTNIPLSRGLGSSAACIVGGIVGANALLNEKMTIKDMLKIAVDIEGHPDNVAPALLGGVIISIKDMENIIYSRINVKSQLKYAVMVPDFKVSTELSRKVLPNEYSREDALFNISRCSMLVSALNNGENEKLRYLFEDKIHQPYRKKLINNIDSIFLKAKEYGSLGEFISGSGSTLIAVLEEADENFILKMKTYLDSLKDGWRIFEVENDNNGAVII
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_STUS1
Sequence: MIELDLQCASTGAAPAAADLQRWCELALRQRSGDSELTIRLVDEEEGRELNRTWRQKDYATNVLSFPADVPDEFLDIPLLGDLVICVPVVEREAAEQGKTLDAHWAHLVIHGCLHLLGYDHIEDAEAEEMEALERQLLAELGHPDPYAEDSPETGICKDS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
Protein: GCS23_RHOJR
Sequence: MLASDPRKVGVEEEFHLIDLKTRRLTTRAPELLARLPDDVYVDELQQCVVEVNSGVYADLDGLRSDLERHRRLLVDAAEDLGIGVAAAGSVPLALPAEMHVTGTQRYGRMLADYQVLAREQLICGTQVHVDLPDRDEAVQVAHRVAPHMPVLLALSASSPFRSDGADTGYASARTLLWLRWPSTGPAAPVSSAAEYGALIDDLVASGVISDPGMAYFDVRPSVKLPTLELRVCDSCPRLDTVLLVAALFRALVEREVEGLRAGRKGVEVLPTLTRAALWRAARSGLEEELVDVTVPQARPASELVGDFVNSLRPQLEETGDWDRVVELSAEATAHGSSAARQRQALGRRGRLTDVVDLLLAETAGRTEHLPDVEVPPPREPGPKSTGAGRTRRYWSARFWDRGDTADMTWTESTELDEKKLVEWRRDLHAHPELSFEERRTTGVVRDHLVGLGLEPVLMPGGTGLWCDVGPETGECIALRADLDALPVAETTGLPFESRVPGVSHACGHDAHTTMLMGAASVLTKYPPPTRVRLVFQPAEETTPGGAVDTIAAGALDGVSKIFALHCDPHLEVGKLSTRTGPITSSNDSVTVRLWSAGGHTARPHLTGDLIHATAVLVTGLASVLDRRIDARTATVLTWGKVAAGQVANSVPESGELVGTLRSASRETWASLEPLVTDAICHLLAPYNVRYELSYLRGVPPVVNDPDCTADLREAIESVVGFDHLAEAHQSSGGEDFAWYLEKVPGAMARLGVWDGTGTRQELHQPGFNLDERAMIHGVRTLVALTRLEDQSG
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-3, Gamma-glutamylcysteine synthetase 2-3, GCS 2-3, Gamma-GCS 2-3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: KAD_TRIEI
Sequence: MVKLVFLGPPGAGKGTQASLIADFYKVPHISTGDILRSNVAERSPLGIKAKDYMDKGDLVPDQLILDMVKERLENPNAQNGWILDGFPRTVTQAEEFFKKYESEGEEAKSSSSFHVINLQVPDDVLVARLLSRKREDDQEETIRNRLQVYYQQTQPLIEFYQAREQLIIIDGNNPIETVTNAIKQEVDKIT
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_CARHZ
Sequence: MIDERKRKILMAIVQDYISTAEPVGSRTIAKKYDLGISPATIRNEMADLEEMGYLEQPHTSAGRIPSVLGYRYYVDYLMEKPSLSREEEEFIRKVYEDKINSIGDLLEKTGKVLSSLTRYTAVVLSPEAGKVPLKHLQLVLLQPGKVLLIIVLEDGTLHHRAFEVPGDITAQDLEKVSAILNAKLYGVNPEKIRYSLIKEIYYELAQHQNLINITLELISNLNQDNQEHKIILGGLINLFNQPEFKNVEKVKTLLSILEQEEKIREIFSQLNVGVNVKIGSELNLKEIEDCSMIAAGYFSYGNSVGFIGVLGPTRMEYAKTVATVEFLSKYLSEIIGNKNF
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RIBBA_CORGB
Sequence: MSEHEQAHSQLDSVEEAIADIAAGKAVVVVDDEDRENEGDIIFAAELATPELVAFMVRYSSGYICAPLTAKDADRLDLPPMTAHNQDARGTAYTVTVDANTGTTGISATDRAHTLRLLADPEADRTDFTRPGHVVPLRAREGGVLVRAGHTEAAVDLARAAGLRPAGVICEVVSEEDPTGMARVPELRRFCDEHDLKLISIEQLIEWRRKNEILVERQVETVLPTDFGTFKAVGYRSIIDGTELVAIVAGDVASDGGENVLVRVHSECLTGDVFGSRRCDCGQQLHESLRLIQEAGRGVVVYMRGHEGRGIGLLAKLRAYQLQDEGADTVDANLALGLPADAREFGTSAQILYDLGVRSLNLISNNPAKKVGLEGHGISIASRTPIPVAVHEDNVRYLKTKRDRMGHDLPDVALWEQEHPEN
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: AVR2B_CHICK
Sequence: MSASWLTLAVLCATLGAGPGHGEAETRECIYYNANWELEKTNQSGVERCEGEKDKRLHCYASWRNNSGSIELVKKGCWLDDFNCYDRQECVATEENPQVFFCCCEGNYCNEKFTHLPEVTGPEVIYEPPPPTPSLLNILVYSLLPIAVLSVAILLAFWMYRHRKPPYGHVDINEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDYVAVKIFPIQDKQSWQSEREIFNTPGMKHENLLQFIAAEKRGTNLETELWLITAFHDKGSLTDYLKGNIISWNELCHVAETMARGLSYLHEDVPWCKGEGHKPAIAHRDFKSKNVLLKNDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCRAVDGPVDEYMLPFEEEIGQHPSLEDLQEVVVHKKMRPVFKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERIAQIRKSVNGTTSDCLVSIVTSVTNVDLPPKESSI
What is the function of this protein?
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.  Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.  Receptor for activin A, activin B and inhibin A.  May modulate neuropeptide expression in dorsal root ganglia (DRG) neurons and ovarian follicle development.
What are the official names of this protein?
Activin receptor type-2B, Activin receptor type IIB, ACTR-IIB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y2377_BACP2
Sequence: MEHGEKQITIVDDNGNEQLCEVLFTFESDHFNKSYVLYYPISEQDNEEIEIHASSFTPNENGEDGELEPIETDEEWDMIEETLNTFLDQEEEDEE
What are the official names of this protein?
UPF0473 protein BPUM_2377.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: LEPA_RHOP5
Sequence: MTTAPIDNIRNFSIVAHIDHGKSTLADRLIQITGGMTDREMAGKEQVLDSMDIERERGITIKAQTVRLNYHAKDGKDYIFNLMDTPGHVDFAYEVSRSLAACEGSLLVVDASQGVEAQTLANVYHALDAGHEIVPVLNKVDLPAAEPEMIKQQIEDVIGLDASDAVMISAKTGFGVPEVLEAIVTRLPPPKGDRTASLKALLVDSWYDVYLGVVVLVRVVDGVMKKGQRIRMMGTNAAYDLERVGYFTPKMTAVDELGPGEIGFITAAIKEVADTRVGDTITDDRKPITEMLPGFKPAIPVVFCGLFPVDADDFETLRAAMGKLRLNDASFSFEMETSAALGFGFRCGFLGLLHLEIIQERLSREFDLDLIATAPSVIYKMKLNDGSEIEIHNPVDMPDVVRIQEIDEPWIEATILTPDEYLGSVLKLCQDRRGNQKELTYVGARAMVKYDLPLNEVVFDFYDRLKSVSKGYASFDYHLTDYKPADLVKMQILVNAEPVDALSMLVHRTRAEGRGRAMVEKMKELIPPHMFVIPIQAAIGGKIIARETVRALRKDVTAKCYGGDVTRKRKLLEKQKEGKKKLRQFGKVDIPQEAFIAALKVDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PCP2_CALS4
Sequence: MKILVTAFDPFGGESINPSYEVLKNLKDNIEGAEIVKIQVPTVFYLSVEKAIEKIKEVNPDAVLSIGQAGGRYDISVERVAINIDDARIPDNIGQQPIDTPIDPEGAPAYFATIPIKEIVEEIKKENIPASISNTAGTYVCNHLMYGILNYIHKNKLNIKAGFIHIPYLPVQVLNKPSTPSMSLGDMVKAIETAIKVIVKSCKKSR
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase 2, 5-oxoprolyl-peptidase 2, Pyroglutamyl-peptidase I 2, PGP-I 2, Pyrase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_BACC7
Sequence: MPKRLDINTILVIGSGPIVIGQAAEFDYSGTQACQSLKEEGYKVILVNSNPATIMTDTATADKVYIEPLTLEFVSRIIRKERPDAILPTLGGQTGLNMAVELAKSGVLEECGVEILGTKLSAIEQAEDRDLFRTLMQDLNEPTPPSEIIHNLDEAYGFVNEIGYPVIVRPAFTLGGTGGGICHNEEELIEIVTSGLKHSPVTQCLLEKSIAGCKEIEYEVMRDSNDNAIVVCNMENIDPVGVHTGDSIVVAPSQTLSDREYQMLRNTSLRIIRALGIEGGCNVQLALDPYSFQYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIVNPVTQKTYACFEPALDYVVSKIPRWPFDKFESANRTLGTQMKATGEVMSIGRNLEESLLKAVRSLELGIYHLELDHLKELDKETMKKRIIKADDERLFIVAEAIRQGVTKEEINEWCEMDFFFLQKVENIVNMEREVKANVGNMEVLQTAKEMGFSDHYIAAAWNKTEREIYDMRKENNMTPVFKMVDTCAAEFESATPYYYSTYADENESIVTDRKSVVVLGSGPIRIGQGVEFDYATVHSVWAIKEAGYEAIIINNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEKPEGVIVQFGGQTAINLAAKLEEHGVKILGTSLEDLDRAEDRDKFEAALTKLGIPQPVGKTATTVEQAVAIAEEIGYPVLVRPSYVLGGRAMEIVYRQEELLHYMKNAVKVHADHPVLIDRYMVGKEIEVDAISDGENVFIPGIMEHIERAGVHSGDSIGVYPPQSLSEKLKEQIIEHTIALGKGLNIVGLLNIQFVVFKDQVYVIEVNPRASRTVPFLSKITGVPMANVATKVILGQNLVEQGYGTGYHPEEKEVYVKAPVFSFAKLRSVDTTLGPEMKSTGEVMGKDLTLEKALYKGLVASGINIPTHGSVIITVADKDKEEAMEIAKRFHEIGYNLLATAGTAQSLAEQNIPVQVVNKIDSEEYNLLDIIRQGKAQFVINTLTKGKQPARDGFRIRRESVENGVACLTSLDTTRAILRVLESMTFSAHSMKEITQTKRHEVVHA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: MURB_STAA3
Sequence: MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISLLSLDHIEVSDDAIIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQGSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIGEHPKES
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCOA4_HUMAN
Sequence: MNTFQDQSGSSSNREPLLRCSDARRDLELAIGGVLRAEQQIKDNLREVKAQIHSCISRHLECLRSREVWLYEQVDLIYQLKEETLQQQAQQLYSLLGQFNCLTHQLECTQNKDLANQVSVCLERLGSLTLKPEDSTVLLFEADTITLRQTITTFGSLKTIQIPEHLMAHASSANIGPFLEKRGCISMPEQKSASGIVAVPFSEWLLGSKPASGYQAPYIPSTDPQDWLTQKQTLENSQTSSRACNFFNNVGGNLKGLENWLLKSEKSSYQKCNSHSTTSSFSIEMEKVGDQELPDQDEMDLSDWLVTPQESHKLRKPENGSRETSEKFKLLFQSYNVNDWLVKTDSCTNCQGNQPKGVEIENLGNLKCLNDHLEAKKPLSTPSMVTEDWLVQNHQDPCKVEEVCRANEPCTSFAECVCDENCEKEALYKWLLKKEGKDKNGMPVEPKPEPEKHKDSLNMWLCPRKEVIEQTKAPKAMTPSRIADSFQVIKNSPLSEWLIRPPYKEGSPKEVPGTEDRAGKQKFKSPMNTSWCSFNTADWVLPGKKMGNLSQLSSGEDKWLLRKKAQEVLLNSPLQEEHNFPPDHYGLPAVCDLFACMQLKVDKEKWLYRTPLQM
What is the function of this protein?
Enhances the androgen receptor transcriptional activity in prostate cancer cells.  Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma.
What are the official names of this protein?
Nuclear receptor coactivator 4, NCoA-4, Androgen receptor coactivator 70 kDa protein, 70 kDa AR-activator, 70 kDa androgen receptor coactivator, Androgen receptor-associated protein of 70 kDa, Ret-activating protein ELE1.
Protein: CCME_IDILO
Sequence: MNPRRKQRLTWVAILVIGVSVATGLMLYALSQSIDLFYTPTELVEGKGKDKQKPQVGQRMRVGGMVVEGSVERDRETLEVSFKITDIGPEVTVLYQGILPDLFREGQGIVAQGELIEPTVLKASEVLAKHDEEYMPPELAEQMKGIKHVNPNTVEKGEGQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: DOHH_CHICK
Sequence: MVTEEEVTAIGRTLLDAAQPLPARFRALFTLRNLGGPAAIDCIVRGFADSSALLKHELAFCLGQMRDRAAIPALLGVLQDSQQEPMVRHEAGEALGAIGDPEVLDVLRRYSEDPVVEVAETCQLAVRRLEWLQEHGEEPGSSPYRSVDPAPPAEETDVATLRAVLLDESRPLFDRYRAMFALRNLGGRDAVLALADGLRAGSALFRHEIGYVLGQMQDEACVPQLTAALRSRAENPMVRHECAEALGSIARPSCLETLRAFAQDEERVVRESCEVALDMYEYENGPQFQYADGLCRLQA
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A.  This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine.  Hypusination is unique to mature eIF-5A factor and is essential for its function.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
Protein: PSBL_SACHY
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MEND_HAEDU
Sequence: MSTNSSFNRSWAKVILNALLRYGVKHFCIAPGSRSTPLTLEALQLQHTQQAECHSHFDERGLAFFALGMAKATNDPVAIIVTSGTAVANLYPALIEASLTQHKLIVLSADRPPELIGCGVNQAITQPGIFADYPIANIHLPKASTDYNASWLAATIEQACVNQQQQGGVIHINAPFAEPLYETDENEINNTPWLKPLQSWLIKPTAKWLNSQSIQSEVSMHENWDYWRTKRGVIIVGKLPVEQGVGIKAWAETLGWCLLTDIQSCVDASLPYADIWLSNNTVHERLLNADIVIQFGSQIISKRVNKYLADFKGEFWQVDEYQRYLNPFAHRQTRFVAKAHHFLRVHPPLRQKPWLLEPLALSQFCASFIEQQVGGSLNEASLAHHIEQVLATNGNLFIGNSLFVRLVDALCKLPEGYPVYTNRGASGIDGLIATMAGIAKASGQPTVGVVGDISALHDLNSISLLSKINHPSILFVINNSGGAIFDMLPVEARVKEQFYRLSHNYEFSQVAAMFGIEYIRPFTWADLKAKLKLAYGRKSATIVEIKVNDQDGSNLYKSLIKQISQAEIA
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: ZKSC1_RAT
Sequence: MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDASLQETPPPDPEVFRQRFRRFCYQNTFGPREALNRLKELCHQWLRPEVNTKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGVVPLDPVQESSSFDHHEAAQSHFKHSSRKPRLLSPRALPATHVPAPQHEGNPRDQAMASALLTADSQAMVKIEDMAVSLILEEWGCQNLARRNLNRDSRQMNLGTVFSQGSENRNGSESTSKAEVKGDSTSHGEIAGRFQKEFGEKREQQGRVIERQQKNPEEKTGKEKKAPGPPTAKEKKPTTGERGPREKGKGLGRSFSLSANFNNTPEEIPSGAKTHRCDECGKCFTRSSSLIRHKIIHTGEKPYECNECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASEYSPASLDTFGAFLKSCV
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein with KRAB and SCAN domains 1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SLMA_YERPG
Sequence: MAEKENTKRNRREEILQALAQMLESSDGSQRITTAKLAANVGVSEAALYRHFPSKTRMFDSLIEFIEDSLMSRINLILQDEKETFNRLRLILLLVLGFAERNPGLTRIMTGHALMFEQDRLQGRINQLFERIEMQLRQVLREKKLRDGQGFIHDEALLATQLLAFCEGMLSRFVRSEFRYCPTQEFDSRWPLIVAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MTGA_SALDC
Sequence: MSKRRIAPLTFLRRLLLRILAALAVFWGGGIALFSVVPVPFSAVMAERQISAWLGGEFGYVAHSDWVSMADISPWMGLAVIAAEDQKFPEHWGFDVPAIEKALAHNERNESRIRGASTLSQQTAKNLFLWDGRSWLRKGLEAGLTLGIETVWSKKRILTVSLNIAEFGDGIFGVEAAAQRYFHKPASRLSVSEAALLAAVLPNPLRYKANAPSGYVRSRQAWIMRQMRQLGGESFMTRNQLN
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: VP41_ISOHA
Sequence: DDLSDFNPKV
What are the official names of this protein?
Venom peptide Sh41.
What is the protein family that this protein belongs to?
Belongs to the SA81-like family.
What are the subcellular locations of this protein?
Secreted.
Protein: SRY_PENEL
Sequence: MFRTVNGEDYSPAVQQRNILDFGKAHSLLWTDNGSANDRCETGGNCRESGQDRVKRPMNAFIVWSRDQRRKVALENPQMQNSEISKRLGYDWKMLTEAEKQPFFEEAQRLRAMHRDKYPGYKYRPRRKAKEATEIASRRLFSTVQPNAHRGDVVPLPIQGRLRQGHTFTNGKPVKPLTAHEHKQLTPATGASQQLDKPAPQ
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: DEFB8_BOVIN
Sequence: VRNFVTCRINRGFCVPIRCPGHRRQIGTCLGPQIKCCR
What is the function of this protein?
Has bactericidal activity.  Active against E. coli ML35 and S. aureus 502A.
What are the official names of this protein?
Beta-defensin 8, BNBD-8, BNDB-8.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTS2_STAES
Sequence: MRQKTLDVLEFEKIKSFVADETISDLGREKVQEMAPASNFDTVEFQMNETDEISQIYNKHRLPSLSGLAKVSPLVHRASIGGVLNVGELNRIKRLVQVQNQFKTFYNQMLEEDEEVKYPILHDKMNHLPILTDLFKEINEKCDAHDLFDHASYTLQSIRSKISRTNQRIRQNLDRIVKNQGNQKKLSDAIVTVRNDRNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPNSVVEMNNQISRLRNDEAVERERILTELTGLVSAESDALLVAESVMGQIDFLIAKARYARTIKGTKPTFKEERTIYLPNAFHPLLDKDTVVANTIEFIDDVETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSIFENVYCDIGDEQSIEQSLSTFSSHMKNIVEILQDADQNSLILFDELGAGTDPSEGAALAMSILDYVRRLGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEQEINAMIESLEHNSKRVDQQRIELDRLVREAQETHDALSKQYQQYQNYEKSLMEEAKEKANQRVKSATKEADEILKELRNLRDHKGAEVKEHELIDKKKQLDDQYEAKSIKQHVQKKKYDTIHAGDEVKVLSYGQKGEVLELVGNEEAVVQMGIIKMKLPIEDLEKTKKKKEKPTKMVTRQNRQTIKTELDLRGYRYEEALNELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVRQFRGGMPNEGGFGVTVAELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.