PharMolix/UniProtQA huggingface dataset:
Protein: EFP_BORPD
Sequence: MKTAQELRVGNVVMVGKDPLVVQKAEYNKSGRNAAVVKLKFKNLLTGSGSESVYKADEKFDVVVLDRKECTYSYFGDPMYVFMDEEYNQYEIEAESMGDALNYLEEAMPVEVVFYDGRAISVELPTILVREITYTEPAVRGDTSGKVLKPAKINTGFELNVPLFCAIGDKIEIDTRTNEYRSRVN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_OLEA2
Sequence: MKDNIHPTVYKAKLVCACGNEIDTTSTKGEVVNVEICSSCHPFYTGKQRFVDTAGRIDRFRKKYAKFSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PYRE_ENTFA
Sequence: MTKVAKKIAKDLLDIEAVFLNPNEPFTWASGIKSPIYCDNRITMSYPAVRKEIAEGLAAKIKETFPEVEVIAGTATAGIPHAAWVADILGLPMVYIRSKAKDHGKGNQIEGRISEGQKMVVIEDLISTGGSVLEAAEAAEREGATVLGVAAIFTYELPKGTANFADKQMTLLTLTNYSTLIDAALEANYIEEKDVTLLQEWKKDPENWGK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TSAD_PSYIN
Sequence: MRILGIETSCDETGIAIYDDQLGLLSHQLYSQVELHADYGGVVPELASRDHVRKTIPLIKEALVAANCTKESLDGIAYTAGPGLVGALLVGSCIGRSLAYAWNIPAIAVHHMEGHLLAPMLEENRPEFPFLALLVSGGHTLMVEVENIGEYQVLGESIDDAAGEAFDKTAKLLGLDYPGGPRLAKLAEKGEPKRFIFPRPMTTKPGLDFSFSGLKTFAANTIAKEGKDPQTQADIALAFQDAVIDTVAIKCKRALKQTGLKRLVVAGGVSANLSLRSQLAVLMKSLGGEVFYPRNEFCTDNGAMIAYAGMQRLKAGHFEGLGIQAKPRWPLDQLLSVRSEL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECM14_PENRW
Sequence: MRLFSPILVASTLIPLISAVPAGSSITPPPPLQPSYFTHSSPRPWARLRDWIIGSIWDIDHKHRSSKHSSPPSNIHDRYGSDVVLRFHLRQPDEAEALASASQVLFLDIWAITSEFVDIRLADDMIPSLLDLLPLTLRTSYTPLMDNLADEIYASYPSRHRSDSDFKSGLASAELKTISNCDLFFQEYQPLSVITQWMRLMASMFSSHVRMTSVGVSYEGRDIPALRLGTSHNTETTSGPRKTILIVGGSHAREWISTSTVTYVAYSLITHYGYSPAVTRLLHEYDWVLIPTINPDGYVYSWESDRLWRKNRQPTGLPLCPGVDLDRAWDYEWDGESTRSNPCSENYAGAEPFEALESQRLAQWAQNQTAHGGAEIVGFLDLHSYSQQILYPYSYSCSSVPPTLESLEELALGLAKAIRQTSHESYDVTSACEGILTQGAAAGITSGGSALDWFYHKLHTRFSYQIKLRDRGSYGFLLPSEHIVPTGKEIFRALLTFGKFVWGEEASDISLEDMTGDQIPLN
What is the function of this protein?
Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.
What are the official names of this protein?
Inactive metallocarboxypeptidase ecm14.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Vacuole. Secreted.
Protein: TMED7_HUMAN
Sequence: MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
What is the function of this protein?
Potential role in vesicular protein trafficking, mainly in the early secretory pathway.  Appears to play a role in the biosynthesis of secreted cargo including processing and post-translational modifications.
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 7, p24 family protein gamma-3, p24gamma3, p27.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Single-pass type I membrane protein. Note=Cycles between compartments of the early secretatory pathway.
Protein: PYRE_JANMA
Sequence: MNNLRQEFIKFSVETGVLRFGEFVTKAGRTSPYFFNAGLFNQGRTLAMLAEFYAQTLIDSGIEFDMLFGPAYKGITLASATAVALANKGRDVSFAFNRKEAKDHGEGGTMVGAKLQGRVVIIDDVISAGTSVRESVDMIRAAGATPCAVMIALDRMERSGADGALSAHSAVQEVSNTYGMPVVSIGNLSDLFEYLSNAGADSEQAKYKEAVAAYRQRYGVA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CH60_PHATC
Sequence: MAKKILYQDNARRALERGMEIMVEAVSVTLGPKGRNVVLEKSYGSPQIVNDGVTIAKEIKLLDHIENTGVSLIRQAASKTNDVAGDGTTTATVLAYAMVKEGLKNVAAGANPISIKLGMEKASQYLVTQINEFAQPVEDIQSIQQVASISAGNDEIIGSLIADALSKVGKEGVISLEEGKGIVTELEITEGMKLEKGFISPYFITNTEKMEVSYDNPYILLTDKRITLVQQDLLPILEQITKTKRPLLIIAEDVEKEALATLILNKLRGIINVVAVRAPGFGELRKQMLEDIAILTGGTVITQDAGLSLDNIQLNLLGQARRIIVNKDSTTIVSDGQTLNEINIRCEQLRKQVNIADTGYEKEKLQDRIAKLSGGIAVIRVGAVTETEMKDKKLRLEDAINATRAAVEEGIVPGGGATLTHLSENLVTWAKNNLKEDELIGAMIISRAILAPLRRIAENAGINGPVIIEKVQQQEFEIGYNAAKNTFGNMYTEGIVDPAKVTRSGLQNATSIASMILTTECIIVDDVKSSNES
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, chloroplastic, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NAMA_BACCZ
Sequence: MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLVHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDSLIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPSAIPFNETMKTPVEMSKHQIKDTILAFQQAAIRSKQAGFDVIEIHGAHGYLINEFLSPLSNKRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKEQGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIAANELGFELEEPHQYERAPGKISTNK
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: ENGB_STAA1
Sequence: MKVNPNNIELIISAVKEEQYPETELSEVALSGRSNVGKSTFINSMIGRKNMARTSQQPGKTQTLNFYNIDEQLIFVDVPGYGYAKVSKTQREKFGKMIEEYITKRENLQLVIQLVDLRHDPTQDDILMYNYLKHFDIPTLVICTKEDKIPKGKVQKHIKNIKTQLDMDPDDTIVSYSSIQNNKQQQIWNLIEPYIS
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: DDX1_DROME
Sequence: MTAFEEFGVLPELGMATDELDWTLPTDVQAEAIPLILGGGDVLMAAETGSGKTGAFCLPILQIVWETLRDLEEGKAGKGGAIGGAVTPWTMSFFDRGNALAVTPDGLRCQSREFKEWHGCRATTGVRGKGKFYFEATVTDEGLCRVGWSTQQANLDLGTCRMGFGFGGTGKKSNNRQFDDYGEAFGKADVIGCLLDLKNQEVSFTKNGQNLGVAFRLPDNLAKETFYPAVVLKNAEMQFNFGKTDFKYAPGNGFVGACQAGPEHSKANPITGPAAGAPSAKPAPNAPQAIIMEPSRELAEQTYNQIEKFKYHLSNPEVRSLLLIGGVRLEEQKAQLMQGTHIVVGTPGRLEEMINSGLVLLTHCRFFVLDEADALLKQGYTELIDRLHKQIPKITSDGRRLQMVVCSATLHAFEVKKMAERLMHFPTWVDLKGEDAVPETVHHVVCLVDPQMDTTWQSLRQPIGTDGVHDRDNVHPGNHSKETLSQAVKLLKGEYCVHAIDKHNMDRAIIFCRTKQDCDNLERFLRQRGGKHYSCVCLHGDRKPQERKENLEMFKRQQVKFLICTDVAARGLDITGLPFMINVTLPDDKTNYVHRIGRVGRAERMGLAISLVATVPEKVWYHGEWCKSRGRSCNNTNLTEVRGCCIWYNEPNLLAEVEDHLNITIQQVDKTMDVPVNDFDGKVVYGQKNLRTGSGYEDHVEQLVPTVRKLTELELQSQSLFLKRLKV
What is the function of this protein?
Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes.  Possesses 5' single-stranded RNA overhang nuclease activity (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase Ddx1, DEAD box protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX1 subfamily.
Protein: TTCA_BRUA1
Sequence: MNAFDADITEHADSSGCHPLFRDVPATVEFNKLRKRLLRLTRQAIEDFAMVKPGDRWMVCLSGGKDSYGLLALLLDLKWRGLLPVELLAVNLDQGQPNFPKHILPDFLTRYGIEHRIEYQDTYSIVTDKLPETSTYCSLCSRLRRGNLYRIAREEGCSAIVLGHHREDILETFFMNLFHGGRLAAMPPKLLNDEGDLMVFRPLAYAAEDDLEKFANAMQFPIIPCDLCGSQDGLQRNAMKAMLIDIEKRMPGRKDTMIRALTNVRPSHLLDRKLFDFAGLMANGEKGSDDALW
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMCB_CHLPS
Sequence: MSKLIRRVVTVLALTSMASSFASGKIEAAAAESLATRFIASTENADDNVFQATAKKVRFGRNKNQRQEQKHTEAFCDKEFYPCEGGQCQPVDATQESCYGKMYCVRVNDDCNVEISQSVPEYATVGSPYPIEILAVGKKDCVNVVITQQLPCEVEFVSSDPATTPTSDSKLIWTIDRLGQGEKCKITVWVKPLKEGCCFTAATVCACPELRSYTKCGQPAICIKQEGPECACLRCPVCYKIEVCNTGSAIARNVVVDNPVPDGYTHASGQRVLSFNLGDMRPGDSKCFCVEFCPQKRGKVTNVATVSYCGGHKCSANVTTVVNEPCVQVNISGADWSYVCKPVEYTIVVSNPGDLKLYDVVIEDTAPSGATILEAAGAEICCNKAVWCIKEMCPGETLQFKVVAKAQSPGKFTNQVVVKTNSDCGTCTSCAEVTTHWKGLAATHMCVIDTNDPICVGENTVYRICVTNRGSAEDTNVSLILKFSKELQPVSSSGPTKGTITGNTVVFDALPKLGSKESVEFSVTLKGIAPGDARGEAILSSDTLTVPVADTENTHVY
What is the function of this protein?
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin.  It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan (By similarity).
What are the official names of this protein?
Large cysteine-rich periplasmic protein omcB, Large-CRP, 60 kDa cysteine-rich OMP, 60 kDa outer membrane protein, Cysteine-rich outer membrane protein.
What are the subcellular locations of this protein?
Periplasm.
Protein: TIAS_PYRHO
Sequence: MLLHIGLDDTDSPNGMCTTYLGALLYRELSRFGEPVDLPKLIRLNPNIPYKTRGNGAVSLTFDILEDYLNEAKELVVKTVKKLAEVEHENTNPGIAFLEGEVPEILRRFAIKALREHVTIDEAEKIAKKAGAEIVKLKLGRGIIGALASIGYPLNNYTYELLAYRKLENREKVRRVDRDSVFEMDRKFYPFTYDNVDPFKKTILITPHGKDPVLVGIRGIDKGKVLLAYENVIINENVEMIQLFKTNQSTDDHLVWKKIGDIKLYDNVIVKGKVASKYWERGRHVFFEIEDETGKIRVAAFEPTKKFRNYVRKLLPGDEVIVAGGVKEHEGVLTINLEKFYPIKLVPKVEYRKPKCPKCGGTMKSKGDYLKCKRCGYKMPKVLIPVKLPRDLERKIYEVPPDARKHLSRPLVLPKSEDKFIGPL
What is the function of this protein?
ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
What are the official names of this protein?
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS, tRNA(Ile2)-agm2C synthetase, tRNA(Ile2) agmatidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the TiaS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_LISW6
Sequence: MKKIILLGATGSIGTQTLAIIRENPEKFQLVALSFGRNMERGRAIIQEFKPKMVAVWHTRDRITLESEFPNVKFFNGLEGLREVATYLDGDVLLNAVMGSVGLLPTLDAIEAGKSIAIANKETLVTAGHIVMRAAREKNISLLPVDSEHSAILQALNGENPERIEKLVLTASGGSFRDKTRGELSEVTVKEALKHPNWNMGNKLTIDSATMFNKGLEVMEAHWLFGVDYDDIEVVIQRESIVHSMVQFVDGSFIAQLGTPDMRMPIQYALTYPDRLFIPYEKNFRITDFSALHFEKVDYERFPALKLAYNAGKIGGTMPTVLNAANEIAVAGFLNGQVAFYNIEALVENALNRHTSISEPDLDTILQVDQETRAYVKTLL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: SHO1_CLALS
Sequence: MGFRMANFLGDPFAISTVSFGVIAWIVAIAGAGSSASDNFPRFTWWGLVYEILLIIMVFLLYLNNTIELYKFTLVGLLSVGFLYTTNSTNNLIYSSNSGNLCCAAGCILLSMLNFLWIVYFGGHPESPSNQFIDSFAMKSSYAQQLPSEKNDDHEFAVPRSASGSQGFGVSDSRHSQLTNSKSGYMSSSQLNGLENFSHTNVQNTGTVGASNPASMPNTVYNTNGTNTADSNFAVPVSTFRYKARALYSYDASPDDINEISFVKDEILEVDDIDGKWWQARRANGQVGICPSNYVKLLD
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.  Mediates resistance to oxidative stress and plays a crucial role of in the pseudohyphae morphogenetic transitions.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UPPP_MYCLB
Sequence: MTAVSAMSWWQVIVLAVVQGLTEFLPVSSSGHLAIVSRILFTGDAGASFTAVSQLGTEVAVLVYFGRDIVRILHAWCRGLTVTLHRTADYWLGWYVIIGTIPICILGLVCKDEIRSGIRPLWVVATALVAFSGVIAFAEYVGRQNRCIEQLNWRDALVVGVAQTLALIPGVSRSGSTISAGLFLGLDRELAARFGFLLAIPAVFASGLFSIPDAFHPITEGMSATGAQLLVATVIAFVVGLVAVSWLLRFLVQHNLYWFVGYRIVVGVGVLILLAVKTVAAT
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y630_STRU0
Sequence: MSQKKIDLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPTLVPKFLEIIEQNNDNKRVALVVDMRSRTFFKEITLILDQIEQNFAIDFRILFLDATDNELVSRYKETRRSHPLAADGRVMDGIKLERELLAPLKSMSQNVVDTSDLTPRQLRQVITEQFSSDSNSASFRVEVMSFGFKYGIPLDADLVFDVRFLPNPYYLPELREKTGLDQEVYDYVMKHQESNDFYKHLVELILPILPGYQKEGKSLLTIAIGCTGGQHRSVAFAHRLAETVKKDWPVNESHRDKDKRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SUB0630.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: ISCS_SALPK
Sequence: MKLPIYLDYSATTPVDPRVAEKMMQFLTLDGTFGNPASRSHRFGWQAEEAVDIARNQIAELVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLNELEAAMRDDTILVSIMHVNNEIGVVQDIATIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRIRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMETEMARLRGLRNRLWNGIKDIEEVYLNGDLEQGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGMNDELAHSSIRFSLGRFTTEEEIDYTIDLVRKSIGRLRDLSPLWEMYKQGVDLNSIEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.  Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_ECOUT
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GUAA_CHRVO
Sequence: MDKILILDFGSQVTQLIARRVREAHVYCELHSFDMPIEEIQAFAPKAIILSGGPNSVYESDYQADPKLFELGVPVLGICYGMQFMAQTLGGKVESGDKREFGYAQIKARHHSKLLEGLQDQIDDAGNGFLDVWMSHGDKVTQLPAGFQVIAETPSCPYAAMADEARGFYGVQFHPEVTHTKRGTEMIHRFVLHVAGCKPSWTMPNYIDEAVKKIREQVGDEEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGKMVMEMFAQNLGVKVVHVQAEADFMAKLAGETDPEKKRKIIGAEFIEVFDRESGKLTNAKWLAQGTIYPDVIESAGAKTKKAHTIKSHHNVGGLPEDMNLKLLEPLRELFKDEVRQLGVALGLPHDMVYRHPFPGPGLGVRILGEVKKEYADLLRQADAIFIEELRNTVDEKTGKNWYELTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVVTSDFMTAHWAELPYSLLGRASNRIINEVRGINRVVYDVSGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MSHC_THECD
Sequence: MRSWPAPEVPNLPEAGLPGPALPLHLHDTATGTVRPTRPGPTARMYVCGITPYDATHLGHAATYLAFDLVNRVWRDGGHKVCYVQNVTDVDDPLLERAEQTGQDWRELADREIALFRDDMTALRILPPDHYVGAVEAIPLIVEMIERLRSRGAVYEVNGDLYFPISADPDFGRVSGLTTEQMLPLFAERGGDPQRRGKKDPLDALLWRAQRPGEPSWESPFGPGRPGWHVECSAISIHHLGMAFDVEGGGSDLAFPHHEMSASHAQVATGRHPHAKAYVHTGMVGLDGQKMSKSLGNLVFVSRLRADGADPMAVRLALLAHHYRSDWEWTGEDLPRATARLERWRAAVQLPAGPPAAAVAAEVRRHLSQDLDAPSALVTVDRWAEQALAGAGERDPAAPAQVRAVVDALLGVAL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: HIS3_BURM9
Sequence: MNAEAKPGDWLGKVRWDANGLVPVIAQDAATNDVLMFAWMNRDALAKTIELKRAVYYSRSRQRLWFKGEESGHVQHVHEVRLDCDEDVVLLKVEQVEGIACHTGRRSCFFQKFEGTVDDGEWVAVDPVLKDPEHIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_JANMA
Sequence: MSFTVIIPARLASTRLPNKPLADLGGKPMIVRVAERAMQSGAAQVIVATDHADIFAACVQHKVAVQMTRADHPSGTDRIAEVAALIGLPDEAVVVNVQGDEPLIDPSLIAATATLISRDVPMATAAHAISEIEEVFNPNVVKVVLDKSGRALYFSRATIPWHRDGFAVSKDAIPAGYAPLRHIGLYAYRNAFLQEYPQLSVSPLEQLEALEQLRVLWHGVPIAVHVTPHAPVTGVDTPEDLQRVRQFFAQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_BIFA0
Sequence: MAEVKLISAESVTEGHPDKICDQISDAILDDMLRQDPHSHVAVETSATKGQFWVFGEVTSKGYSDIQSIVRDTVRRIGYTSSVIGLDADSCGVLVSLSEQSPEINQGVSRIDSDRENAVSREERYEAQGAGDQGVMFGYASDETDVLMPLPIHLAHRLAYRLAEVRKNGEVKFLRPDGKTQVTIEYDEENRPLRVDTVLISTQHDPEVSQEALREDLREHVIEPVLDEVLGDAVKHDDYRVLVNPTGSFIMGGPAADAGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSAAYAARWVAKNIVAAGLAHKVEVQVAYAIGVAEPVSINVETYGTEADGVTREQIQEAVRKVFDLRPAAIVDELDLLRPIYSKTAAYGHFGREDDDFTWEHTNKVDELKRAIATLVD
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCCS_PENCH
Sequence: MADKITDEYAVGIDPEIYANNPAYSSLFNPYIHKQTIIADHVSVQCHIDLNGIDAVGSKFGNLNAHAGNFTSLCAPNCLPERFALVAYTVEYAFLHDDETDNAADQEALLLENKMLHQALNQSGMTSVSTRVSDKAQRKSEVQAKIAAEYLRLDPVFGEWFLNKWQTFTACVKDVRSLEFPSLDDYLEFRIVDAAADWTLYNFRWGSGITLTPEEEKLADPMSYVAYAELCLVNDLFSWDKEYASHIKSNGDVPLVNAVHIVAVTQGLTHCAAKAVVQAEVRAHEERFCQLKEQYEATDKPSHEVLRWLRLLEHSMAGNWVWSLCVPRYCKVDRNPYKDHLEKYGSDAVRVLTPLDRLCWSKQEIKEMKRNQLKEPSSSTYKTHFSPLEPNPGPEQTRLTISQTQQQRPVLNPYTYINSLPSKNVRQTLIAALNSWYKVPVKSLLIIEGAVNFLHNSSLLLDDIQDGSVLRRGRPVAHQIFGVGQTINTATYLMNEALYLIQMLSPSAVSAYTDEMRNLQLGQGRDLYWSYHTHVPTPAQYISMVDGKTGGLFRLISRLMRSEATKNSDLDISQFATLLGRHFQIRDDYQNLQSEDVTNPHIVSLYAPRANMLLQYTKNKGFCDDLDEGKVSFPVILSMQSPGFSNTALSSVFKGSRKGETLSLEMKQYMLEEITARGAFSETKAVLRKLHTELLSLLMETEKKAGGVENWALRLLIMKLDIVEEKKVAPPKSDSHWGVNQRRAWKGGQKNGRPIDKACFLRAMEEALQK
What is the function of this protein?
Bifunctional terpene synthase converts dimethylallyl diphosphate (DMAPP) and isopentenyl diphosphate (IPP) into a cyclopiane-type diterpene (PubMed:30179018).  The C-terminal prenyltransferase (PT) domain of PcCS catalyzes formation of geranylgeranyl pyrophosphate (GGPP), whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GGPP to the cyclopiane-type diterpene (PubMed:30179018).
What are the official names of this protein?
Cyclopiane-type diterpene synthase, CS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FPP/GGPP synthase family.