PharMolix/UniProtQA huggingface dataset:
Protein: FTSI2_PSEAE
Sequence: MSSQRRNYRFILVVTLFVLASLAVSGRLVYLQVHDHEFLADQGDLRSIRDLPIPVTRGMITDRNGEPLAVSTEVASIWCNPREMAAHLDEVPRLAGALHRPAAALLAQLQANPNKRFLYLERGLSPIEASEVMALGITGVHQIKEYKRFYPSSELTAQLIGLVNIDGRGQEGTELGFNDWLSGKDGVREVAINPRGSLVNSIKVLKTPKASQDVALSIDLRLQFIAYKALEKAVLKFGAHSGSAVLVNPKSGQILAMANFPSYNPNNRASFAPAFMRNRTLTDTFEPGSVIKPFSMSAALASGKFDENSQVSVAPGWMTIDGHTIHDVARRDVLTMTGVLINSSNIGMSKVALQIGPKPILEQLGRVGFGAPLSLGFPGENPGYLPFHEKWSNIATASMSFGYSLAVNTAELAQAYSVFANDGKLVPLSLLRDNPQNQVRQAMDPQIARRIRAMLQTVVEDPKGVVRARVPGYHVAGKSGTARKASGRGYADKSYRSLFVGMAPASDPQLVLAVMIDSPTRIGYFGGLVSAPTFSDIMAGSLRALAIPPDNLQDSPAVADRQHHG
What is the function of this protein?
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity).  Binds penicillin (PubMed:9045804).
What are the official names of this protein?
Probable peptidoglycan D,D-transpeptidase PbpC, PBP3x, Penicillin-binding protein 3 homolog, PBP3 homolog.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family. FtsI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HRCA_BACAA
Sequence: MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITYSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLAPQNLPNDEIVQIKDLFVERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANMLSQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSRVISLLQLFTRQFTDGLKK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: HAT1_NEUCR
Sequence: MSGDDDWWTSSNEALLVSLVTPSDTGVKTLDTFHPEYTNNIFGEKEQIFGYKGLRINLQYNASDMLPNLKVSYKKKYQPTADEEALDINEVLSEFLPEIAFQKQSDFETRLKSIPDNWTPPGTLVTSFTNKDGEYEVYSGKITDPAVKQLLNRIQILVPFFVDGGTPIDMEDPDVDRWTIYFLYNKRPLLNQPDKFSYHFAGYSTLYRYYAFQPPAESESKTPTDTPTFSVDGDFDLDTLPCRTRISQFIIIPPFQQKGLGSRLYSIIYQQYLKHEPTIELTVEDPNEAFDDMRDLADLAFLSKQPEFQALKIDTSVEIPEEGKAPSNIVDQAAWEACRKKFKIVPRQFARVLEMYLMSQLPESVRPGLGAPEDEDYEEQSGRSKSKGHEKALPKPTPEDEHTYRLWMMLVKRRLYVHNRDALGQLELKERREELAKVFAGVEFDYARLLIKAEEQGKLAQADGETAGDQVPATPSAANGKRKLDEVEQAEGTAAASSKKAKVESGHA
What is the function of this protein?
Catalytic component of the histone acetylase B (HAT-B) complex.  Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.  Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.  Involved in DNA double-strand break repair.
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UBE4A_PONAB
Sequence: MTDQENNNNISSNPFAALFGSLADAKQFAAIQKEQLKQQSDELPASPDDSDNSVSESLDEFDYSVAEISRSFRSQQEICEQLNINHMIQRIFLITLDNSDPSLKSGNGIPSRCVYLEEMAVELEDQDWLDMGNVEQALFARLLLQDPGNHLINMTSSTTLNLSADRDAGERHIFCYLYSCFQRAKEEITKVPENLLPFAVQCRNLTVSNTRTVLLTPEIYVDQNIHEQLVDLMLEAIQGAHFEDVTEFLEEVIEALILDEEVRTFSEVMIPVFDILLGRIKDLELCQILLYAYLDILLYFTRQKDMAKVFVEYIQPKDPTNGQMYQKTLLGVILNISCLLKTPGVVENHGYFLNPSRSSPQEIKVQEANIHQFMAQFHEKIYQMLKNLLQLSPETKHCILSWLGNCLHANAGRTKIWANQMPEIFFQMYASDAFFLNLGAALLKLCQPFCKPRSSRLLTFNPTYCALKELNDEERKIKNVHMRGLDKETCLIPAVQEPKFPQNYNLVTENLALTEYTLYLGFHRLHDQMVKINQNLHRLQVAWRDAQQSSSPAADSLREQFERLMTIYLSTKTAMTEPQMLQNCLNLQVSMAVLLVQLAIGNEGSQPIELTFPLPDGYSSLAYVPEFFADNLGDFLIFLRRFADDILETSADSLEHVLHFITIFTGSIERMKNPHLRAKLAEVLEAVMPHLDQTPNPLVSSVFHRKRVFCNFQYAPQLAEALIKVFVDIEFTGDPHQFEQKFNYRRPMYPILRYMWGTDTYRESIKDLADYASKNLEAMNPPLFLRFLNLLMNDAIFLLDEAIQYLSKIKIQQIEKDRGEWDSLTPEARREKEAGLQMFGQLARFHNIMSNETIGTLAFLTSEIKSLFVHPFLAERIISMLNYFLQHLVGPKMGALKVKDFSEFDFKPQQLVSDICTIYLNLGDEENFCATVPKDGRSYSPTLFAQTVRVLKKINKPGNMIVAFSNLAERIKSLADLQQQEEETYADACDEFLDPIMSTLMCDPVVLPSSRVTVDRSTIARHLLSDQTDPFNRSPLTMDQIRPNTELKEKIQRWLAERKQQKEQLE
What is the function of this protein?
Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases.  May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase.  Mediates 'Lys-48'-linked polyubiquitination of substrates.
What are the official names of this protein?
Ubiquitin conjugation factor E4 A, RING-type E3 ubiquitin transferase E4 A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin conjugation factor E4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIGM_RHOER
Sequence: MTYEVLEQINAMADDIFAEGIEAERIGRVADDTAKKMKAIGSIRMLQPKEHGGMEAHPREFAETVMRMASLNPSAGWVHGIVGVHPWQLAFADPKVQQEIWGSDPDTWMASPYMPGGMCIPTDGGYKFSGRWQFSSGTDHCDWAFLGAMACDKDGNMEMPPRMLHVIIPRTDYEIIEDSWDVMGLRGTGSKDLVVKDAYVPDYRVMDCDEVIDGTAVRKYGRTETLYLMPWSNMFPLGITAATIGICEGMLFHANEYQAGRINAQGTAVKDDPYTLFAIGQATADIRAARDTLLANVDRMWDRVDAGKEVTFEQRAEGRQTQVQAAWRAINAIDQVYPRCGGNALRMDKPLQRFWRDAHAGQHHAIHVPGTVFHAASLSRLGADPQGPLRAMI
What is the function of this protein?
Involved in pigment production acting as a hydroxylase that transforms indole to indoxyl, resulting in the formation of indigo.
What are the official names of this protein?
Pigment production hydroxylase.
Protein: SPPA_HAEIN
Sequence: MFQVLKFCWKVLCFIRDLVMNVVFLGFVLLLVAIISFSSGGKKSTALTSEGALLLNLDGYLADNRDETLRWQDALSELNGEHVPRKISTFDVVFAIQQAEDDPKIKGLVLDLNYFEGADLPALDFIGGAISHFKDAGKPVIAYADNYSQGQYYLASFADEIYLNSIGSVDIHGLSQENLYFKEMLDKLAVTPHIFRVGTYKSAVEPFLRNDMSAEAKANMQRWLGEMWNNYVLSVSENRNIKKDRILPNAKQYLAELKALKGNSTAYAQQRGLVTDVVTRLDLDKKLSALFGKGSDGKANLIEFDDYLTQLPDRLEHYNVPNKIAVVNVEGTIIDGESDEENAGGDTIARILRKAHDDNSVKAVILRVNSPGGSAFASEIIRQETENLQKIGKPVIVSMGAMAASGGYWISSTADYIIADSNTITGSIGIFTMFPTFENSIKKIGVHADGVSTTELANTSAFSPLAKPVQDIYQTEIEHGYDRFLEIVSKGRQLSKTQVDKLAQGQVWLGSDAFQNGLVDEIGSFNEAVNKAEQLVNQRQDTAVQDFSVEWFTDDNVSLISTLLSDTKKGAQEQLVKWLGLPAPIQKLQKELNILTKFNDPKGQYLYCLNCGKVK
What is the function of this protein?
Digests cleaved signal peptides in vitro, its in vivo function is unknown.  This activity is necessary to maintain proper secretion of mature proteins across the membrane (By similarity).
What are the official names of this protein?
Protease 4, Endopeptidase IV, Protease IV, Signal peptide peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: BIOF_BURM7
Sequence: MNPLATLEQGLADIDAQGLRRCRRVADTACGAHMTVDGRAIIGFASNDYLGLAAHPRLVEAFAEGARRYGSGSGGSHLLGGHSRAHATLEDELAAFSGGFSDAPRALYFSTGYMANLAALTALAGRGATIFSDALNHASLIDGARLSRANVQIYPHGDADALDARLRACDAPTKLIVSDTVFSMDGDVAPLARLVALAETHGAWLVVDDAHGFGVLGPQGRGALAAHGLRSPNLVYVGTLGKAAGVAGAFVVAHETVIEWLVQRARSYIFTTAAPPSVACAVSASLAVIASDEGDARRAHLGALIKRTRAILRATHWQPVDSHTAVQPLVIGSNEATLAAMAALDAQGLWVPAIRPPTVPAGTSRLRISLSAAHSFDDLARLEAALVTPIGAAA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: NUP82_SCHPO
Sequence: MASTIMSQEVSWTDILEKHPALRWIKPIPEDWEIFPKHLCAFESFLYVAVGQEVRSLDCRLLKHKNEASHKNFYKKLFNPELDFMIEQICLSKNGRFLAVVGKSKIVILGLRSKLSEQNPLAESVSNFGESVNNFSNSEHQENGTNSLKLSEVTICSVAVINPSSQIVSVRFHPLGKSGRSLVVLTETSLLLYEAGNGVLMPDYEIPLKLTHQASNSFDADVDLHIPTAFCFSNVSQGWGVFTIYILTRGGDVFSVCPVMPANAMIPQDVLKQIRLILTKKEDDADAENHRRNVHWITKLLGEAALANDLSTSFVISEGSSELFDSSDYVSVRRPDDFSFIPSMQGPFLLQPAVADDELIEDYCDIYSFGMNPIDVLAIGGSEGRLDLLLLVSEVSGRWSKLNDHGLASMKLIVSQVHSLYLSNNNPYMVLQPDIQSPYSLIAYHANGLHVVDIESWARDLNLNFENSEFLNNEEENDEDELSNVLVSIPSRTSVLERLDTNPLNESTDAVVGCAQLYYPSLGKILISLTRNWQTTVFDDSDLATMGVNKESLSNEMDYSKSLGTSSLEQVDDLDEKLTYTPLYVSLLEKTPFTDPSIPSLVERTIVPAELQNEITVSSASLRFLGKVVARYRETLNLLDHGCSELHHRLKLQREEYERQQNHIYKLSDRISNFREKAWSTEHLEHLTSDMSMCEKRIDQVLQRVMDLRVPDLSDKEKQFIKEIGNYKEKVTGERGIEKRVETLKTLLQRTKPRDAQTTLVASSSDMRLAAIEQLQKLLAQQSLSIKELKTKTVSFQRLLQTS
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity).
What are the official names of this protein?
Nucleoporin nup82, Nuclear pore protein nup82.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RLUE_XANAC
Sequence: MLVLLNKPYGVLSQFSDRSQPPKRTLAEFGLPPDVYAAGRLDHDSEGLLVLTDDGALAHRLTDPRHKQPKTYWVQVEGAPQAEHLQALRDGVALNDGPTRPAQVRMLDPAPQLWPRDPPVRVRKTVPDAWLELQITEGRNRQVRRMTAAVGLPTLRLVRVAIGDWRLDALAPGQWRAEATTNARPSRSRR
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase E, rRNA pseudouridylate synthase E, rRNA-uridine isomerase E.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: MIAB_PROM0
Sequence: MLTKTKSDEIKTQKDSTTGSYWITTFGCQMNKADSERMAGTLEKMGYTRADNELNADLVLYNTCTIRDNAEQKVYSFLGRQAKRKHKTPRLKLVVAGCLAQQEGESLLRRVPELDLVMGPQHVNNLENLLGKVDLGNQVVATEETFISEDITSARRESSICGWVNIIYGCNERCSYCVVPSVRGKEQSRYPNAIKSEIQKLADDNFKEITLLGQNIDAYGRDLPGTTKEGRKENTLTDLLYYIHDVKGIRRIRFATSHPRYFSKRLIQACYELDKVCEHFHIPFQSGNDEILKQMSRGYSIKKYKNIIENIRSLMPDASITADAIVAFPGETEKQYQDTLKLISEIGFDQVNTAAYSARPNTPAAVWTNQLSEEVKKARLQEINDLVEKTARSRNQRYIDNIESVLIEGLNPKNSSQIMGRTRTNRLTFVEIPKNINFNFSLGDEINVRINEARPFSLTGELSL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POLS_JAEV5
Sequence: MTKKPGGPGKNRAINMLKRGLPRVFPLVGVKRVVMSLLDGRGPVRFVLALITFFKFTALAPTKALLGRWKAVEKSVAMKHLTSFKRELGTLIDAVNKRGRKQNKRGGNEGSIMWLASLAVVIACAGAMKLSNFQGKLLMTINNTDIADVIVIPTSKGENRCWVRAIDVGYMCEDTITYECPKLTMGNDPEDVDCWCDNQEVYVQYGRCTRTRHSKRSRRSVSVQTHGESSLVNKKEAWLDSTKATRYLMKTENWIIRNPGYAFLAAVLGWMLGSNNGQRVVFTILLLLVAPAYSFNCLGMGNRDFIEGASGATWVDLVLEGDSCLTIMANDKPTLDVRMINIEASQLAEVRSYCYHASVTDISTVARCPTTGEAHNEKRADSSYVCKQGFTDRGWGNGCGLFGKGSIDTCAKFSCTSKAIGRTIQPENIKYEVGIFVHGTTTSENHGNYSAQVGASQAAKFTVTPNAPSITLKLGDYGEVTLDCEPRSGLNTEAFYVMTVGSKSFLVHREWFHDLALPWTSPSSTAWRNRELLMEFEGAHATKQSVVALGSQEGGLHQALAGAIVVEYSSSVKLTSGHLKCRLKMDKLALKGTTYGMCTEKFSFAKNPADTGHGTVVIELSYSGSDGSCKIPIVSVASLNDMTPVGRLVTVNPFVATSSANSKVLVEMEPPFGDSYIVVGRGDKQINHHWHKAGSTLGKAFSTTLKGAQRLAALGDTAWDFGSIGGVFNSIGKAVHQVFGGAFRTLFGGMSWITQGLMGALLLWMGVNARDRSIALAFLATGGVLVFLATNVHADTGCAIDITRKEMRCGSGIFVHNDVEAWVDRYKYLPETPRSLAKIVHKAHKEGVCGVRSVTRLEHQMWEAVRDELNVLLKENAVDLSVVVNKPVGRYRSAPKRLSMTQEKFEMGWKAWGKSILFAPELANSTFVVDGPETKECPDEHRAWNSMQIEDFGFGITSTRVWLKIREESTDECDGAIIGTAVKGHVAVHSDLSYWIESRYNDTWKLERAVFGEVKSCTWPETHTLWGDDVEESELIIPHTIAGPKSKHNRREGYKTQNQGPWDENGIVLDFDYCPGTKVTITEDCGKRGPSVRTTTDSGKLITDWCCRSCSLPPLRFRTENGCWYGMEIRPVRHDETTLVRSQVDAFNGEMVDPFSAGPSGDVSGHPGGPSQEVDGQIDHSCGFGGPTCADAWGHHLH
What is the function of this protein?
May play a role in neuroinvasiveness.
What are the official names of this protein?
Structural polyprotein.
What are the subcellular locations of this protein?
[Peptide pr]: Secreted. SUBCELLULAR LOCATION: [Small envelope protein M]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Note=ER membrane retention is mediated by the transmembrane domains. SUBCELLULAR LOCATION: [Envelope protein E]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Note=ER membrane retention is mediated by the transmembrane domains. SUBCELLULAR LOCATION: [Non-structural protein 1']: Secreted. Host endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Note=Located in RE-derived vesicles hosting the replication complex.
Protein: ENL22_ARATH
Sequence: MAQSSGHVSYVAVTVPIAIVMTVLCLFLANAVTYARRPTTYIVGGDDGWDPVVPMDTWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSSGDDKIQLNYGYNYFIGTYTPEDCTTGLKMAIKALAPR
What is the function of this protein?
May act as a carbohydrate transporter.
What are the official names of this protein?
Early nodulin-like protein 22, AtENODL22, Phytocyanin-like protein ENODL22.
What is the protein family that this protein belongs to?
Belongs to the early nodulin-like (ENODL) family.
Protein: PKP4_ARATH
Sequence: MVGLDSSHLLRDKILCFSSRSHINNQHKKTSYALSLNHMKLPIQRTLAFALARGKGEAESFSRLEATFGDNTSTECTWSFDFPDSKDAMSHLKSEADLSGSNGANNVASVIEKLNALRSHLLAAEKWNASQLHLCDSKYLECATNLVHYMALRSLDIEQLNSHLASLGLSSLDNNNLDVLAHLNASINLLMNDQNAVTESWTNVYPKGKSTKKNDKGRVLSYKESLLGKLREGRSTHIMVTIGEEATLSETFITDILKAGTSVIRINCAHGDPSIWGEIIKRVRRTSQMLEMPCRVHMDLAGPKLRTGTLKPGPCVMKISPKKDAYGNVVSPALVWLCLTGTEPPAHVSPDATISVQGQDFLAGLQIGDSIRLCDARGRKRRLKISKEFHVFNSTGFVAECFDTAYIESGTELSVKGKKGRRLVGRVVDVPPKESFVRLKVGDLLVITREGSLDEPSVTVPGAHRLTCPSGYLFDSVKPGETIGFDDGKIWGVIKGTSPSEVIVSITHARPKGTKLGSEKSINIPQSDIHFKGLTSKDIKDLDYVASHADMVGISFIRDVHDITVLRQELKKRKLDDLGIVLKIETKSGFKNLSLILLEAMKCSNPLGIMIARGDLAVECGWERLANMQEEIIAICKAARVPVIMATQVLESLVKSGVPTRAEITDAANAKRASCVMLNKGKNIVEAVSMLDTILHTKLIYKKSDSENLH
What are the official names of this protein?
Plastidial pyruvate kinase 4, chloroplastic, PKp4.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: TYRR_HAEIN
Sequence: MTISKFNPQKPFECFIVQSEAMKSAVENAKRFAMFDAPLLIQGETGSGKDLLAKACHYQSLRRDKKFIAVNCAGLPDEDAESEMFGRKVGDSETIGFFEYANKGTVLLDGIAELSLSLQAKLLRFLTDGSFRRVGEEKEHYANVRVICTSQVPLHLLVEQGKVRADLFHRLNVLTINVPALRDRMADIEPLAQGFLQEISEELKIAKPTFDKDFLLYLQKYDWKGNVRELYNTLYRACSLVQDNHLTIESLNLALPQSAVISLDEFENKTLDEIIGFYEAQVLKLFYAEYPSTRKLAQRLGVSHTAIANKLKQYGIGK
What is the function of this protein?
Transcriptional regulator of the TyrR regulon, which includes a number of genes coding for proteins involved in the biosynthesis or transport of the three aromatic amino acids, phenylalanine, tyrosine and tryptophan.  These three aromatic amino acids act as effectors which bind to the TyrR protein to form an active regulatory protein (By similarity).  Acts by binding specifically to TyrR boxes in the promoter region of the target genes (PubMed:9226720).  Can efficiently repress the transcription of the aroF promoter, but lacks the ability to function as a transcriptional activator (PubMed:9226720).
What are the official names of this protein?
HTH-type transcriptional regulatory protein TyrR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT2_HUMAN
Sequence: MDFREILMIASKGQGVNNVPKRYSLAVGPPKKDPKVKGVQSAAVQAFLKRKEEELRRKALEEKRRKEELVKKRIELKHDKKARAMAKRTKDNFHGYNGIPIEEKSKKRQATESHTSQGTDREYEMEEENEFLEYNHAESEQEYEEEQEPPKVESKPKVPLKSAPPPMNFTDLLRLAEKKQFEPVEIKVVKKSEERPMTAEELREREFLERKHRRKKLETDGKLPPTVSKKAPSQKESVGTKLSKGSGDRHPSSKGMPLPHAEKKSRPSMANEKHLALSSSKSMPGERIKAGSGNSSQPSLREGHDKPVFNGAGKPHSSTSSPSVPKTSASRTQKSAVEHKAKKSLSHPSHSRPGPMVTPHNKAKSPGVRQPGSSSSSAPGQPSTGVARPTVSSGPVPRRQNGSSSSGPERSISGSKKPTNDSNPSRRTVSGTCGPGQPASSSGGPGRPISGSVSSARPLGSSRGPGRPVSSPHELRRPVSGLGPPGRSVSGPGRSISGSIPAGRTVSNSVPGRPVSSLGPGQTVSSSGPTIKPKCTVVSETISSKNIISRSSNGQMNGMKPPLSGYRAAQGPQRLPFPTGYKRQREYEEEDDDDDEYDSEMEDFIEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSLRLGMQEDLEEMRREEEEMQRRRAKKLKRR
What is the function of this protein?
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053).  Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053).  Binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053).  Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053).  Modulates RNA polymerase 1-mediated transcription (By similarity).  Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026).
What are the official names of this protein?
Protein SPT2 homolog, Protein KU002155, SPT2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SPT2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: OSR1_HUMAN
Sequence: MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGTVSSLVDARFQLPAFPWFPHVIQPKPEITAGGSVPALKTKPRFDFANLALAATQEDPAKLGRGEGPGSPAGGLGALLDVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC
What is the function of this protein?
Transcription factor that plays a role in the regulation of embryonic heart and urogenital development.
What are the official names of this protein?
Protein odd-skipped-related 1.
What is the protein family that this protein belongs to?
Belongs to the Odd C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENGB_LACH4
Sequence: MIIKSSNYAVSAVREDQYPKDNLPEIALSGRSNVGKSSLINTLLNRKNLARTSSQPGKTQTLNFYLINDEFYLVDVPGYGYARVSQKKRQEFGEMIQDYLETRPNLKGLVILIDSRHEPTKDDIAMYNYAQYLNLPILVVCTKIDKIKKSQVNKVMSRLKKNIDLNYDYVTVLTFSSVTKLHVAELGNWIEEKISK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: HSCB_BURM1
Sequence: MVSLKDSHFDLFHLPAQFALDEAALDAAYRAVQTQVHPDRFAAAGDAQKRIAMQWATRANEAYRTLRDPLKRATYLLSLRGVDIGAENNTAMEPAFLMQQMEWRESIEDAAAARNVDALDALLAELRDEKRARLERLGTLLDSGADQAAAEAVRQLMFIERVASEVGAQIERLET
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: YJCO_SHIFL
Sequence: MKKIIALMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADSWFSSGDLSKAEYWAQKAADSGDADACALLAQIKITNPVSLDYPQAKVLAEKAAQAGSKEGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKADDDKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDTGCEEFEKLTNG
What are the official names of this protein?
Uncharacterized protein YjcO.
Protein: CCA5A_XENLA
Sequence: MSEGKKRSRGGLAIISPPKRRSQRKSTSDSPIPEPIMKRSITVKKIMPRKTLAAIVNTGSQSTPKVSNVPPAPRRSSRISPKIQKENAFSEQSQIVHKDVPGQSSAPKINVLSPIPVNIQLSPKQDNRDIIMSQKVRRSYSRLEMSLNSSSSLYSPTRKTDSSDTSTPNVVLKSGRSSLFGFDKLLNSEMPDGELKKSNGVTRKKNTKERILGTVLPEQPDHNIPGVVLAKQKRRKRKVAIIEKSDLDEWAAFMNAEFEEAEKFDLTVE
What is the function of this protein?
Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin.  May antagonize the action of wapl which stimulates cohesin dissociation from chromatin.  Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.  Required for efficient DNA double-stranded break repair (Probable).
What are the official names of this protein?
Sororin, Cell division cycle-associated protein 5-A, Xp35.
What is the protein family that this protein belongs to?
Belongs to the sororin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Associates with nuclear chromatin from S phase until metaphase and is released in the cytoplasm upon nuclear envelope breakdown.
Protein: RL22_IDILO
Sequence: MEAIAKHQFARVSAQKGRLVADQIRGLPVEKALDILAYSPKAAAGLIKKVLESAIANAEHNEGADIDELKVSRVFLDEGPTMKRIKPRAKGRADRIFKRTSHITVVVSDS
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RF1ML_HUMAN
Sequence: MRSRVLWGAARWLWPRRAVGPARRPLSSGSPPLEELFTRGGPLRTFLERQAGSEAHLKVRRPELLAVIKLLNEKERELRETEHLLHDENEDLRKLAENEITLCQKEITQLKHQIILLLVPSEETDENDLILEVTAGVGGQEAMLFTSEIFDMYQQYAAFKRWHFETLEYFPSELGGLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHTSTMTVAILPQPTEINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPTGVVSECQQERSQLKNKELAMTKLRAKLYSMHLEEEINKRQNARKIQIGSKGRSEKIRTYNFPQNRVTDHRINKTLHDLETFMQGDYLLDELVQSLKEYADYESLVEIISQKV
What is the function of this protein?
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG.
What are the official names of this protein?
Peptide chain release factor 1-like, mitochondrial, Mitochondrial translational release factor 1-like, mtRF1a.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
Protein: LRC39_BOVIN
Sequence: MSENVVSTGAVNAVKEVWEKRIKKLNEDLKREKEFQQKLVRIWEERVCLTKLREKVTKEDGRVILKIEKEEWKTLPSSLLKLNQLQEWQLHRIGLLKIPEFIGRFQNLIVLDLSRNTITEIPRGIGLLTRLQELILSYNRIKTVPMELSYCASLEKLELAVNRDISDLPQELSNLLKLTHLDLSMNLFTTIPPAVLNMPALEWLDMGSNRLEQLPDTIERMQNLHTLWLQRNEITCLPETISSMKNLSTLVLSNNKLQDIPVCMEKMTNLRFVNFRDNPLKLEVTLPPSENIEEEEERELFGLQFMHTYIQESRRAGNQVNCSTTSPNSIDADG
What is the function of this protein?
Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress.  May regulate expression of other M-band proteins via an SRF-dependent pathway.  Important for normal contractile function in heart.
What are the official names of this protein?
Leucine-rich repeat-containing protein 39, Myosin-interacting M-band-associated stress-responsive protein, Myomasp.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, M line.
Protein: PHS_SACD2
Sequence: MTDLYQQTCEVCRADAPRVPVDEAEVMLEEIPLWRIQQQEGVKQLARNFKFKNFIEALAFTNTVANLAEEEGHHPKLVLEWGSVEVVWWTHKIKGLHKNDFVMAAKTDKLYEG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.