PharMolix/UniProtQA huggingface dataset:
Protein: FILA_MOUSE
Sequence: PDGSGRSSNRRDRPRQLSPSQSSDSQVHSGVQVEGRRGHSSSANRRAGSSSGSGVQGASAGGLAADASRRSGARQGQASAQGRAGSQGQAQGRVSSSADRQGRRGVSESRASDSEGHSDFSEGQAVGAHRQSGAGQRHEQRSSRGQHGSGYYYEQEHSEEESDSQHQHGHQHEQQRGHQHQHQHQHEHEQPESGHRQQQSSGRGHQGAHQEQGRDSARPRGSNQGHSSSRHQADSPRVSARSGSGGRGQSPDASGRSSNRRDRPRQPSPSQSSDSQVHSGVQVEAQRGQSSSANRRAGSSSGSGVQGAAASGQGGYESIFTAKHLDFNQSHSYYYY
What is the function of this protein?
Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.
What are the official names of this protein?
Filaggrin.
What is the protein family that this protein belongs to?
Belongs to the S100-fused protein family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=In the stratum granulosum of the epidermis, localized within keratohyalin granules. In granular keratinocytes and in lower corneocytes, colocalizes with calpain-1/CAPN1 (By similarity).
Protein: TF2AY_MOUSE
Sequence: MAFINLVPKLYQSVIEDVIEGVRDLFAEEGIEEQVLKDLKKLWETKVLQSKATEDFFRNSTQVPLLTLQLPHALPPALQPEASLLIPAGRTLPSFTPEDLNTANCGANFAFAGYPIHVPAGMAFQTASGHLYKVNVPVMVTQTSGRTEILQHPFQQVLQQLGQPLVIQTTVPTLHPCSLQAATEKSLRMEAVLQPPPILHPPPVDRTHVENAASDRRLLPGNELRPQESSPYLSLPGVGFPPQAALTESSLEPVLGVSASLTQNLHSDPFSQGPPGPLHHHLLESQLQSLKDSIYGCDSTKQLRKAEEPSSLRVSEKNCTSERDLNIRVTDDDINEIIQIDGTGDNSSTEEMGSIRDADENEFPGIIDAGDLNVLEEVDSVSNEDSTANSSDNEDHQINAPEEDPLNSGDDVSEQDVPDLFDTENVIVCQYDKIHRSKNRWKFYLKDGVMCFGGRDYVFAKAIGEAEW
What is the function of this protein?
May function as a testis specific transcription factor.  Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.
What are the official names of this protein?
TFIIA-alpha and beta-like factor, General transcription factor II A, 1-like factor.
What is the protein family that this protein belongs to?
Belongs to the TFIIA subunit 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LOLB_YERP3
Sequence: MPMRKRHFYRLLPLASLLLAACTIPVSKGPATSPTSPQWRQHEQQLQQLGQFETRGAFAYLSDKQKVYARFFWQQTSPERYRLLLTNPLGSTELELVVQPGVTQLTDNQGKRYVSDDPQEMIQKLTGMSIPLESLRQWILGLPGDTPNFTLDDKYRLKKLTYQQNGVTWVVNYQEYNTQVTPPLPSRLELNQDGQRIKLKMDSWTIK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: PSBM_POPTR
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQSD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CHEB2_XANAC
Sequence: MVVDDSAVVRQVLVGVLNDAPGIDVIATAADPLLAIEKMRQHWPDVIVLDVEMPRMDGITFLRKIMSERPTPVVICSTLTEKGARVTMDALAAGAVAVVTKPRLGLKQFLTDSADELVATVRSAARANVKRLAARVTAAPLEAEVKHTADVILPAQSGRALAQTTERIVAIGTSTGGTQALEEVLTALPRVCPGIVIVQHMPEKFTAAFAARLNGLCQIAVKEAANNDRVMPGRALIAPGGKHLLLRRSGAQYFVEVLEGPPVNRHRPSVDVLFRSAARAAGSNALGIIMTGMGDDGAAGLLEMRQAGARTVAQDEHTSIVFGMPKEAIKRGGADRILPLGAMAREIVTQLQ
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASOMP_ACRMI
Sequence: MLAPRLAFVLLLSSYFGSILITSVESSDEVDMEKKTVKMRGSNTSVLVEGDGGKISTLYFEEDDDDDDDEDNEESENEVEDFDDENALSFQVESLQEVDESGKPVKASKSSEIQHSVSSVGSLAFTVSALQNSTTYQNLSAKTVTLQAQLPNMATLELMVVLFLEDGTIKFGNETFKVLSGTMKFNINVTGWQYCDGATVSCLSDSNQPAAVGDNLDLALTVKSEAEDPEEVDDAKRAETGKDPICVDPDDPNEEDDDCPVVYDMGGNSEMVLNKGVLVNNMDYVAMPQGFPNLEKTGMMQKKLTFRLPKTPGSVIIDPSVNIGVPPKKQSGNSGTSIKASSLCFFTLTLLLSVLIAHF
What are the official names of this protein?
Acidic skeletal organic matrix protein, Acidic SOMP.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS7_RALSO
Sequence: MSRRAEVTRNTSETQIRVALDLDGTGKQTLNTGVPFLDHMLDQIARHGMVDLDVTATGDTHIDDHHTVEDVGITLGQAVAKAIGDKKGIVRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRARVGSFDVDLSIEFFRGFVNHAGVTLHIDNLRGVNAHHQIETVFKAFGRALRMAVEIDPRAAGTIPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y922_METPB
Sequence: MAGHSQFKNIMHRKGRVDAVRSKVFSKLAREITVAAKLGTPDPSMNPRLRAAILAARAENMPKDNIERAIKKAVGNDGENYEEIRYEGYGPGGAALIVEAQTDNRNRTASDVRSAFTKSGGSLAETGAVAFMFDRVGVIAFAADVADADTMLEAAIEAGADDVRSDADGHEITCAQDAYGEVSKALEARFGEPRRTGLIWKAQNTIDVDDETGEKLIRLVEVIEDQDDVQNVYVNFALSDALVEKMGA
What are the official names of this protein?
Probable transcriptional regulatory protein Mpop_0922.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC1_METST
Sequence: MTQLEYARKGEITPEMEYVAKTENIDVEKLRKNIASGKVVIPKNVHNNTLPTGIGKDLHTKINANIGSSTEMEDINVELEKLDILLKYGADAVMDLSTGPKLHEIRKAIRDKTNIPLGTVPIYEAGVETTSQDKIIVDMDDDIIFKTIINQAKEGVDFITVHCGITQDAIKAVDDSERLMGIVSRGGALTAAWIMHNERENPLYAEYDYLLEICKEHDVTLSLGDGLRPGCIHDATDIAQIRELTTLGRLVKRSQKAGVQVMVEGPGHVPITQVKANMQIQKTICSDAPFYVLGPLVTDVAPGYDHITAAIGASIAGASGADFLCYVTPAEHLCIPNKEHVKQGVIASKIAAEVSDIAKQIPSTMKREYDMAVARDNFDWEKQFELAIDGETARKYYESTSTSDEEMCSMCGDFCAIKMVKDHEKANKN
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase 1, Hydroxymethylpyrimidine phosphate synthase 1, HMP-P synthase 1, HMP-phosphate synthase 1, HMPP synthase 1, Thiamine biosynthesis protein ThiC 1.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: FUS9_GIBM7
Sequence: MADKSHVNNVPMQGNGAYSSHAALQHEAMLKALPLFRAAAEAISKVDSTRVAIVEYGSAHGNNSLEPMEAILKSIHARSLELLFSDRPENDFCTLSKTVTEWADGLVENQLLHPLFISMIPRSFYQQVIPPKSAHLGFSLAALHHLDHVPQPTEDGQDESKLLQRQAHVDLATFLKLRSKEIVSGGSLILSFVGQASAGYENYGGPVDACRNAMIQMVQQDKIPVSVAQAFRVPTYNRTLSDVKKLMDEFTQIWKVHDLFEDDVMHPAFYELKIQSNPSQEASHKYAEIVIDWMMAVCSGYFTKALQVGSQGGYTKEEEESLLQDWVTRTKELFIRDHKDEEVICSFIYIRLERL
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of the mycotoxin fusarin C (PubMed:17121404, PubMed:22652150).  Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (By similarity).  The roles of the other FUS members are yet undetermined (By similarity).  The fusarin C synthetase FUS1 is responsible for the condensation of one acetyl-coenzyme A (CoA) unit with six malonyl-CoA units and the amide linkage of the arising heptaketide and homoserine, subsequently releasing the first intermediate, prefusarin, as an alcohol with an open ring structure (PubMed:17121404).  The cytochrome P450 monooxygenase FUS8 participates in multiple oxidation processes at carbon C-20 and is able to use the FUS1 product as substrate, resulting in formation of 20-hydroxy-prefusarin (By similarity).  This reaction seems to be essential before the 2-pyrrolidone ring closure can be catalyzed by FUS2, generating 20-hydroxy-fusarin (By similarity).  FUS8 is able to further oxidizes carbon C-20 after ring closure, resulting in the formation of carboxy-fusarin C (By similarity).  As the last step, FUS9 methylates the hydroxyl group at C-21 to generate fusarin C (By similarity).  Fusarin C can then rearrange to epi-fusarin C, the (z)-isomers, and fusarin A and fusarin D (By similarity).
What are the official names of this protein?
Methyltransferase FUS9, Fusarin biosynthesis protein 9.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: GRPE_MYCLE
Sequence: MTEGNPHEQVTVTDKRRIDPDTGEVRSIPLGDTPGGSEPAGMTDRSANSTDTMVDKVAELTSDLQRVQADFANYRKRALRDQQTASDRAKATVISQLLGVLDDFDRAREHGDLDSGPLKSVADKLMSALTGLGLVAFGVEGEDFDPVLHEAVQHEGDGGEGSKPVIGDVLRHGYKLGDQVLRHALVGVVDTIAGDGAETVAIVAPVDSTAKTEQGELGDNVTPHKEDGD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_SALAR
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQVAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLEGRPVMVIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFNMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPIICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEVMAASLKAQLLEDLADLDVLSTDDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPCL4_MOUSE
Sequence: MGKNNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPSIVLLLQCDMQK
What is the function of this protein?
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.
What are the official names of this protein?
Hippocalcin-like protein 4, Neural visinin-like protein 2, NVP-2.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
Protein: HTPG_SHEHH
Sequence: MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDALYEGDGELRVRISADKEKGTVTIEDNGIGMTRDGVIEHLGTIAKSGTAEFFKNMSGDESKDSQLIGQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEGDFTVETITKQSRGTEITLHLRDDEKEFADDYRLRSIITKYSDHISVPVEMYEEGTPAVEATEEGGEAIPATEGHWKLMNKATALWTRNKSDVSDEEYQEFYKYISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMWNRDRKHGLKLFVQRVFVMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALRTAVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAEDFANKERVAGLLRFASTHTGEATANVSLADYVERMKEGQSKIYFIVADSYEAAANSPHLELLRKKGIEVLLMSERIDEWLINHLTEFDGKKLHSVTRGDLELGELEDASEKEAQEKLETESEGLVKRVKDSLGDKVSAVKVTTRLTDTPACVVAGEGEMSTQMIKLMQAAGQDVPESKPTFELNPEHPLVARLNDEQDEQRFAQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COG7_MOUSE
Sequence: MDFSKFLADDFDVKDWINAAFRAGPKDGAAGKADGHAATLVMKLQLFIQEVNHAVEETSLQALQNMPKVLRDVEALKQEASFLKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADKWSTLSADIEETFKTQDIAVISAKLTGMQNSLMMLVDTPDYSEKCVHLEALKNRLEALASPQIVAAFTSQSVDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLATWQELCQSDLPLDRQLTGLYDALLGAWHTQTQWATQVFKNPHEVVTVLLIQTLGALVPSLPMCLSAAVERAGPELELTRLLEFYDTTAHFAKGLEMALLPHLQDHNLVKVVELVDAVYGPYKPFQLKYGDMEENNLLIQISAVPLEHGEVIDCVQELSHSVHKLFGLASAAVDRCAKFTNGLGTCGLLTALKSLFAKYVSHFTNALQSIRKKCKLDDIPPNSLFQEDWTAFQNSVRIIATCGELLRQCGDFEQQLANRILSTAGKYLSDSYSPRSLAGFQDSILTDKKSPAKNPWQEYNYLQKDNPAEYASLMEILYTLKEKGSSNHNLLSASRTALTRLNQQAHQLAFDSVFLRIKQQLLLVSRMDSWNTAGIGETLTDDLPAFSLTPLEYISNIGQYIMSLPLNLEPFVTQEDSALELALHAGKLPFPPEQGDELPELDNMADNWLGSIARATMQTYCDVILQIPEVTPHSTKQLATDIDYLINVMDALGLQPSRTLQNIAALLKAKPEEYRQVSKGLPRRLAATVATMRGVNY
What is the function of this protein?
Required for normal Golgi function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 7, COG complex subunit 7, Component of oligomeric Golgi complex 7.
What is the protein family that this protein belongs to?
Belongs to the COG7 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: URTG_DESRO
Sequence: MVNTMKTKLLCVLLLCGAVFSLPRQETYRQLARGSRAYGDPHATCYKDQGVTYRGTWSTSESGAQCINWNSNLLIRRTYNGRMPEAVKLGLGNHNYCRNPDGASKPWCYVIKARKFTSESCSVPVCSKATCGLRKYKEPQLHSTGGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQERYPPQHLRVVLGRTYRVKPGKEEQTFEVEKCIVHEEFDDDTYNNDIALLQLKSGSPQCAQESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCTSKFLFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDIPGVYTKVTNYLGWIRDNMRP
What is the function of this protein?
Probably essential to support the feeding habits of this exclusively haematophagous animal.  Probable potent thrombolytic agent.
What are the official names of this protein?
Salivary plasminogen activator gamma, DSPA gamma.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUC1_MANSM
Sequence: MENAMSKTLYDKHIDSHTIKELDNEGNVLLYIDRTILNEYTSPQAFSGLREENRDVWNKKSILLNVDHVNPTRPVRDANMTDPGGTLQVNYFRENSKLFDIELFDVTDPRQGIEHVVAHEQGLALPGMVIAAGDSHTTTYGAFGAFGFGIGTSEIEHLLATQTLVYKKLKNMRVTLTGKLPFGTTAKDVIMALVAKIGADGATNYAIEFCGEVIDELSVEGRMTICNMAVECGARGAFMAPDEKVYEYIKGTPRAPKGEMWDLAIAEWRKLKSDNDAVFDKEIHMDCSDLEPFVTWGISPDQADVISGEVPDPNLLPEGQKRKDYQAALEYMGLEPGMKFEEIKISHAFIGSCTNGRIEDLREVAKVLKGRKIAQGVRGMIIPGSTQVRARAEAEGLAKIFIDAGFEWRQSGCSMCLAMNEDVLSPGDRCASGTNRNFAGRQGAGSRTHLMSPAMVAAAAVAGHLVDVRKFVEGD
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit 1, Alpha-IPM isomerase 1, IPMI 1, Isopropylmalate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: Y1987_DEIRA
Sequence: MKHILFPTVSAADAFIADLQSRGVVQPQVGTMNMSRRVQQAAGDTMSTGTTTGTVTTPAATTTTTNTTSYADGGYVDGGGTAEDAGAGAVKGTVAGALTGAAAAVIGTAATVATGGLALPVILGMTALGSGVGAAVGAVGGAAGVDETGGTSYDSYSDSYTTNYEADDAYYNRVNESVNAGGRAVAVDDNVPQDVLMDAVNKHGGEILNS
What are the official names of this protein?
Uncharacterized protein DR_1987.
Protein: CDD_SALA4
Sequence: MHPRFQTAFAQLADNLQSALAPILADHHFPAMLTAEQVSTLKNTAGLDEDALAFALLPLAAACARTDLSHFNVGAIARGVSGNWYFGANMEFLGATMQQTVHAEQSAISHAWLRGEKGLAAVTVNYTPCGHCRQFMNELNSGLDLRIHLPGRAPHTLRDYLPDAFGPKDLEIKTLLMDEQDHGFTLTGDTLTQAAITAANKSHMPYSHSPSGVALECKDGRIFTGSYAENAAFNPTLPPLQGALNLLSLNGYNYADIQRAILAEKGDAALIQWDATAATLKALGCHNIDRVLLG
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: HSLU_BACC0
Sequence: MHLHFTPRQIVEKLDQYIIGQKDAKKAVAVALRNRYRRSKLAENLRDEIAPKNILMIGPTGVGKTEVARRMAKLVGAPFIKVEATKFTEVGYVGRDVESMVRDLVETSVRIVKEEMVVKVQDKAEEQANQRLVEILVPSPEKQSGFKNPLEMLFGGTQNSNQTTDSQEDVEIEKKRQDVERKLAAGLLEDEIVSIEVTEQQSSMFDMLQGTGMEQMGMNFQDALGSFMPKKTKKRKLSVKEARKVLTNEEAQRLIDMDEVTQEAVYRAEQLGIIFIDEIDKIAGKQSNSVDVSREGVQRDILPIVEGSNVATKYGSVKTDYILFVAAGAFHMSKPSDLIPELQGRFPIRVELTKLSTDDFVKILIEPDNALIKQYMALLATEGIEIEFSDEAIRKIAEIAYQVNQDTDNIGARRLHTIMEKLLEDLSFEASEITLEKITITPQYVEEKLATIAKNKDVSQFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEB_ECOSM
Sequence: MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: Y1043_HAEIN
Sequence: MKNEAYYQAYLSHHHISRRGLLRHVFPATKSTIEKTQSRPPFSAREDLFSAVCNGCGECASACPNGLIQLKQQQATLEIDYAPCDLCGKCAEVCPTNALHPNFPGDTLLRPQFSSACLILQNQTCPDCQTACPLQAISSTLEIDNERCNGCGECKITCFVAAITLK
What are the official names of this protein?
Uncharacterized protein HI_1043.
Protein: MIAB_NITSB
Sequence: MKKRLYIETLGCAMNVRDSEHIIAELTQKEDYELTQNLQEADLILINTCSVREKPVHKLFSEIGYFNKKKKEGAKIGVCGCTASHLGEEIIKKAPYVSFVLGARNVSKIRDVIKQEKAVEVDIDYDESTYAFSDFRTSPYKAFINISIGCDKKCTFCIVPNTRGEEISIPPELILQEVRRAVDTGAKEIFLLGQNVNNYGRSFSDKARKVDFTDLLRMVSEIDGVRRIRFTSPHPLHMDDKFLQEFATNPKICKSMHMPLQSGSTKVLRDMKRGYTKEWFLDRAMKLREMVPEVHISTDIIVGFPGESEEDFADTIDVVQKVRFEQIFSFKYSPRPLTPAKDYENQIPDEVASRRLSYLQDLHLQMLDSISEQEKDKVYEVYFEELKPGGYVAGRTDNNWIVKVKGSEELLGEFKSVRITKPGRLSLEGELVG
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALYA_KLEPN
Sequence: MLKSGVMVASLCLFSVPSRAAVPAPGDKFELSGWSLSVPVDSDNDGKADQIKEKTLAAGYRNSDFFTLSDAGGMVFKAPISGAKTSKNTTYTRSELREMLRKGDTSIATQGVSRNNWVLSSAPLSEQKKAGGVDGTLEATLSVDHVTTTGVNWQVGRVIIGQIHANNDEPIRLYYRKLPHHQKGSVYFAHEPRKGFGDEQWYEMIGTLQPSHGNQTAAPTEPEAGIALGETFSYRIDATGNKLTVTLMREGRPDVVKTVDMSKSGYSEAGQYLYFKAGVYNQNKTGKPDDYVQATFYRLKATHGAQR
What is the function of this protein?
Degrades alginates that contain guluronic acid.
What are the official names of this protein?
Alginate lyase, Poly(beta-D-mannuronate) lyase, Poly(mana) alginate lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 7 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IAAD_HORVU
Sequence: MACKSSRSLLLLATVMVSVFAAAAAAAAATDCSPGVAFPTNLLGHCRDYVLQQTCAVFTPGSKLPEWMTSAELNYPGQPYLAKLYCCQELAEIPQQCRCEALRYFMALPVPSQPVDPSTGNVGQSGLMDLPGCPREMQRDFVRLLVAPGQCNLATIHNVRYCPAVEQPLWI
What is the function of this protein?
Part of a complex with inhibitory activity, but CMd is inactive as a separate subunit.
What are the official names of this protein?
Alpha-amylase/trypsin inhibitor CMd, Chloroform/methanol-soluble protein CMd.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I6 (cereal trypsin/alpha-amylase inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YDGD_ECOLI
Sequence: MRTTIAVVLGAISLTSAFVFADKPDVARSANDEVSTLFFGHDDRVPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLALTAGHCLLTPPKGKADKAVALRFVSNKGLWRYEIHDIEGRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPSGITPLPLFEGDKAALTAALKAAGRKVTQAGYPEDHLDTLYSHQNCEVTGWAQTSVMSHQCDTLPGDSGSPLMLHTDDGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLDQLSQK
What are the official names of this protein?
Uncharacterized serine protease YdgD.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
Protein: RL14_YERPN
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGIGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRNEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MARC_CITK8
Sequence: MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAHESPEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRHGVDFPGWVILVAPPLIFLAVSVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH
What are the official names of this protein?
UPF0056 inner membrane protein MarC.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VATA_HALMA
Sequence: MSQATDTDVREDGIIESVSGPVVTARDLDARMNDVVYVGSEGLMGEVIEIEGNITTIQVYEETSGVSPGEPVEGTGSPLSVDLGPGMLDAIYDGVQRPLDVLEEKMGSAFLDRGVDAPGIDLEKTWEFTPEVEEGDEVEAGDIVGTVPETPSIDHKVMVPPDSEGGEVVAIESGNFNVEETVVELDNGEEIQMHQEWPVRQQRPTVEKETPTEPLISGQRVLDGLFPIAKGGTAAIPGPFGSGKTVTQHQLAKWADADIVVYVGCGERGNEMTEVIEDFPELEDPTTGNALMDRTCLIANTSNMPVAARESCVYTGITIAEYFRDMGYDVALMADSTSRWAEAMREISSRLEEMPGEEGYPAYLSARLSEFYERAGYFENINGTEGSVSVIGAVSPPGGDFSEPVTQNTLRIVKTFWALDADLAERRHFPSINWNESYSLYRDQLDPWFEDNVRADWPETRQWAIDTLDEEAELQEIVQLVGKDALPEDQQLTLEIARYLREAWLQQNAFHDVDTFCEPEKTYRIMDAAKTYNDAAFEALDAGVPVEEITDIDAAPRLNRIGVQEDYNEYIDDLEDDIESQLRELY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: GPMB_CROS8
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTEKGERQAMQVAQRAKALGITHIITSDLGRTQRTAEIIAQGCGCDVILDPRLRELDMGILERRHLDTLSEEEEGWRRQLVNGTPDGRIPQGESMQEVSERMHGALNACLDLPPGSRPLLVSHGMALGCLVSTILGLPAYAERRLRLRNCSISRVDYQQSPWLASGWVVETAGDVSHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.