PharMolix/UniProtQA huggingface dataset:
Protein: COBQ_SALEP
Sequence: MTQAVMLQGTASDVGKSVLAAGLCRIFYQDGLRTAPFKSQNMALNSGITSDGKEMGRAQIFQAEAAGITPDVRMNPVLLKPTSDRQAQVVLMGKVATNMDAVSYHDYKPRLREQILAVYNSLAQEYDVIVLEGAGSPAEINLRDRDIVNMGMAEMAQCPVILVADIDRGGVFAAIYGTLALLHKQERDRVKGVIINKFRGDVALLYSGIEQIESLTGVPVLGVMPWLDVDLEDEDGVALQNDKYRGNAPRDITIAIVQLPHISNFTDFNALAAQPDVRIRYIRRPEALTDADLVILPGSKNTLSDLAWLRESGMADALLQTHRQGVPVMGICGGYQMLGDTIVDEVESGLGTQPGLGLLNTITRFAQDKITTQVNATMSGELPSWLAAAAGLPVRGYEIHMGETVLQEGCCTAMTLQKNGCSVADGAVTADGLAFGTYLHGLFDSDAFTRAVVNGLRARKGLAPWETTFCYAEHKARQFDLLAEAMRQHIDIDKIYTIMQQHQEPV
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: SNAA3_LYCMC
Sequence: MQLKIQLLMLVLMIVLTDVYSKDGFIVSKKNCLYRCSQSDERGFCNAVCLRYDADSGYCRTGKCWCDGLPQKANIAMKNKNYC
What is the function of this protein?
Binds voltage-independently at site-3 of voltage-gated sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Neurotoxin LmNaTx3.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SOCS2_RAT
Sequence: MTLRCLEPSGNGADRTRSQWGTAGSPEDQSPEAARLAKALRELSQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPTLQHFCRLSINKCTGTIRGLPLPTRLKDYLEEYKFQV
What is the function of this protein?
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction.  SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway.  Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
What are the official names of this protein?
Suppressor of cytokine signaling 2, SOCS-2, Cytokine-inducible SH2 protein 2.
Protein: GPR4_RAT
Sequence: MDNSTGTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVRQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYSNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMERWVAWMNLYRVFVGFLFPWALMLLCYRGILRAVQSSVSTERQEKVKIKRLALSLIAIVLVCFAPYHALLLSRSAVYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASNKPQEMANASLTLETPLTSKRSTTGKTSGAVWAVPPTAQGDQVPLKVLLPPAQ
What is the function of this protein?
Proton-sensing G-protein coupled receptor couples to multiple intracellular signaling pathways, including GNAS/cAMP, GNAQ/phospholipase C (PLC), and GNA13/Rho pathways.  Acidosis-induced GPR4 activation increases paracellular gap formation and permeability of vascular endothelial cells through the GNA12/GNA13/Rho GTPase signaling pathway.  In the brain may mediate central respiratory sensitivity to CO(2)/H(+).
What are the official names of this protein?
G-protein coupled receptor 4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL15_HALS3
Sequence: MTDKKRRQRGSRTHGGGTHKNRRGAGNRGGRGRAGRKKHEQHNYEDVGKSGFKRPEKTDRDVAVLSVQELDEDIPVLSESGVAEETEFGYRVDARDVVDDGWDADVVKVLGGGQLYEQLEVTADAFSDAAVELIEGEGGDAVVSERASEDDEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: HBA_MELCA
Sequence: VLSPSDKANVKATWDKIGGHAGEYGGEALERTFASFPTTKTYFPHFDLSPGSAQVKAHGKKVADALTNAVAHGDDLPMALSTLSDLHAYKLRVDPVNFKLLSHCLLVTLACHHPAEFTPAVHASLDKFFSTVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RP6L2_ARATH
Sequence: MSDGNMDVDESPVSWKVKSLEKLIDGSSFSSTLSRLSSSSRLIPTSRDFHFYYNFDEFKRPIDEITGTSQSTLATIGDSEQVWGKSMKFPGDVDDVYAEDWLCNVNDELIERFDVSVDEFQRIRKKEKEIGRSVVADDGDDGFQMVYGKKKKPVGNVVTGSAAVNGGGSVIDVKMAERDKNSSGKAKVPFHVPTIKKPQEEYNILVNNANLPFEHVWLERSEDDLRAMHPLEKFSVLDFVDKDVNEMEPVKPLPLEQTPFKFVQEVKDLKELVAKLRSVEEFAVDLEHNQYRSFQGLTCLMQISTRTEDYIVDTFKLRIHIGPYLREIFKDPKKKKVMHGADRDIIWLQRDFGIYVCNLFDTGQASRVLNLERNSLEFLLQHFCGVTANKEYQNADWRIRPLPEEMTRYAREDTHYLLYIYDLIKLELQRMAKDDAHTDSPLLEVYKRSYDVCTQLYEKELLTENSYLHVYGLQAAGFNAAQLAIVAGLCEWRDFIARAEDESTGYVLPNKVLLEIAKEMPDSVGKLRRMLKSKHPYIERNVDSVVSVIRQSMQHYAAFESAALSLKDVSPGNVMDKNIEPISEKKDLHTGDVASPSLKENSSQLESTRDLIMGAANTNEGRGLGSGLFGSAKVSAAVRISKKPSSGLGALLGNAASKKKSRTDEKVKEDVKLEQIRSSVNLSFHSFTEKVPDSKSTSETSPKVYGKPEEMSSTMPASVSKEDGVKELKDDSEEASEIVGTSGRVSESKVSSSEMGDIILLENGDEKKVDAEDEPMSLSELSTNFQKCFKSMNKSKKAQKQTEFLNIEPFDYEAARKEVKFGEGHKGRQGKREAAAGQKKGSTQEQSEFGQGKRRQAFPASGNRSMSFKN
What is the function of this protein?
Acts as an important epigenetic regulator through multiple silencing mechanisms (PubMed:23555312, PubMed:25211139).  Involved in association with RRP6L1 in the silencing of the solo LTR locus.  Controls levels of non-coding RNAs (ncRNAs) from the solo LTR locus.  Seems to function independently of the RNA-mediated gene silencing (RdDM) pathway (PubMed:23555312).  Functions redundantly with RRP6L1 in the regulation of FLC locus.  Participates in the maintenance of trimethylated 'Lys-27' (H3K27me3) at FLC locus via the regulation of antisense long non-coding RNAs (lncRNAs) and the regulation of diverse antisense RNAs derived from the FLC locus.  Seems not involved in the exosomal RNA degradation (PubMed:25211139).  May be involved in poly(A)-mediated RNA degradation (PubMed:18285452).
What are the official names of this protein?
Protein RRP6-like 2, AtRRP6L2.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Cytoplasm. Note=Localizes predominantly in the nucleus.
Protein: ATGA1_HUMAN
Sequence: MNCRSEVLEVSVEGRQVEEAMLAVLHTVLLHRSTGKFHYKKEGTYSIGTVGTQDVDCDFIDFTYVRVSSEELDRALRKVVGEFKDALRNSGGDGLGQMSLEFYQKKKSRWPFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVMNRHEYLPKMPTQSEVDNVFDTGLRDVQPYLYKISFQITDALGTSVTTTMRRLIKDTLAL
What is the function of this protein?
Autophagy factor required for autophagosome formation.  Stabilizes ATG13, protecting it from proteasomal degradation.
What are the official names of this protein?
Autophagy-related protein 101.
What is the protein family that this protein belongs to?
Belongs to the ATG101 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure. Note=Under starvation conditions, it is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.
Protein: HIS7_METRJ
Sequence: MRSASISRKTAETDIAVSVNLDGTGRSNIATGIGFLDHMLDLLARHALFDLDVKVDGDLHIDQHHSAEDCGIALGQAFAKALGDKRGVTRYADIHLPMDEALTRVCVDISGRPFLVFRTTFRVEKIGTFDTELVREWFQAFAMNAGLTLHVETLYGDNAHHIAESCYKGLARALRKAVAIDPREEGRVPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDB_STRR6
Sequence: MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKERAVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDLRVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQGQLAQESQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVIGAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLESSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILLGDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLLRTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAPLETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVLEQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYAIGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSARKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSLVAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALYPAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQLPNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIETIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPHFFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKYQGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYTENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREELNR
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: PYRE_ACTP2
Sequence: MEQYKHDFIEFALSRNVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLAKLGEFYAQAIQASGLNFDVLFGPAYKGIPIATTVAVALVNQFDVDKPCCFNRKEAKDHGEGGNLIGSPLKGRILLVDDVITAGTAIRESMEIINANQAELAGVLIALNRKEKGKGELSAIQEVERDYGCQVFSIIDFDDLIQFIEKSEQYAPYLASMRAYREQYGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: MFS55_MYCBP
Sequence: MRAGRRVAISAGSLAVLLGALDTYVVVTIMRDIMNSVGIPINQLHRITWIVTMYLLGYIAAMPLLGRASDRFGRKLMLQVSLAGFIIGSVVTALAGHFGDFHMLIAGRTIQGVASGALLPITLALGADLWSQRNRAGVLGGIGAAQELGSVLGPLYGIFIVWLLHDWRDVFWINVPLTAIAMVMIHFSLPSHDRSTEPERVDLVGGLLLALALGLAVIGLYNPNPDGKHVLPDYGAPLLVGALVAAVAFFGWERFARTRLIDPAGVHFRPFLSALGASVAAGAALMVTLVDVELFGQGVLQMDQAQAAGMLLWFLIALPIGAVTGGWIATRAGDRAVAFAGLLIAAYGYWLISHWPVDLLADRHNILGLFTVPAMHTDLVVAGLGLGLVIGPLSSATLRVVPSAQHGIASAAVVVARMTGMLIGVAALSAWGLYRFNQILAGLSAAIPPNASLLERAAAIGARYQQAFALMYGEIFTITAIVCVFGAVLGLLISGRKEHADEPEVQEQPTLAPQVEPL
What is the function of this protein?
In association with lipoprotein LprG probably transports triacylglycerides (TAG) across the inner cell membrane into the periplasm; TAG probably regulates lipid metabolism and growth regulation (By similarity).  Confers resistance to several drugs such as rifampicin, clofazimine and novobiocin; is also part of the oxidative stress response and is needed to maintain normal growth characteristics (PubMed:19564371).  Probably an efflux transporter, involved in maintaining correct cell wall permeability.  Probably required with LprG for normal surface localization of lipoarabinomannan (LAM) (By similarity).  Required for optimal growth on cholesterol (PubMed:26155739).
What are the official names of this protein?
Probable triacylglyceride transporter BCG_1471c, MFS-type drug efflux transporter P55.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MKAR_USTMA
Sequence: MAIEQHIDGLLRHVGLRVDHGLTPVSASLVLLAGIGALSVGTFALRLVRLFADVYILPGNSVSKYGANKKDLTRASWAVVTGATDGIGREFALQLARKGFNIVLVSRSPEKLGSVAAEIEAATPGVRTKTQAIDFALGDERQYEGLEHTVKGLNVGVLVNNVGKSHNMPVTFTETSEEEMEDIIEINVVSVLRVSKMIIPGMVDRKRGLVLNLGSFAGQVTTPMLATYAGSKAFLSGWSQALGEEVKRSNVDVSLLNTYFVVSNLSKIRKSSAMIPTPKQYVTQVLKTLGRNGGAVGRPYTATPWPGHALVDWATTFVLPRGWLLSYTYGQQVATRKRALNKAHKAVKSA
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NAR1_SCHPO
Sequence: MAKLSVNDLNDFLSPGAVCIKPAQVKKQESKNDIRIDGDAYYEVTKDTGETSELGIASISLNDCLACSGCITSAETVLVNLQSYQEVLKHLESRKSQEILYVSLSPQVRANLAAYYGLSLQEIQAVLEMVFIGKLGFHAILDTNASREIVLQQCAQEFCNSWLQSRAHKNQNQVTNSVVNEHPLIPHSTSQISGVHSNTSSNSGINENAVLPILSSSCPGWICYVEKTHSNLIPNLSRVRSPQQACGRILKDWAVQQFSMQRNDVWHLSLMPCFDKKLEASRDEFSENGVRDVDSVLTPKELVEMFKFLRIDPIELTKNPIPFQQSTDAIPFWYPRITYEEQIGSSSGGYMGYVLSYAAKMLFGIDDVGPYVSMNNKNGDLTEYTLRHPETNEQLISMATCYGFRNIQNLVRRVHGNSSVRKGRVLLKKRVRSNAQNPTEEPSRYDYVEVMACPGGCINGGGQLPFPSVERIVSARDWMQQVEKLYYEPGTRSVDQSAVSYMLEQWVKDPTLTPKFLHTSYRAVQTDNDNPLLLANKW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1 homolog, Nuclear architecture-related protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRB_STAAR
Sequence: MNHLLSMEHLSTDQIYKLIQKASQFKSGERQLPNFEGKYVANLFFENSTRTKCSFEMAELKLGLKTISFETSTSSVSKGESLYDTCKTLESIGCDLLVIRHPFNNYYEKLANINIPIANAGDGSGQHPTQSLLDLMTIYEEYGYFEGLNVLICGDIKNSRVARSNYHSLKALGANVMFNSPNAWIDDSLEAPYVNIDDVIETVDIVMLLRIQHERHGLAEETRFAADDYHQKHGLNEVRYNKLQEHAIVMHPAPVNRGVEIQSDLVEASKSRIFKQMENGVYLRMAVIDELLK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL13_BART1
Sequence: MATFSQKPTEVVKKWVIIDAENLVLGRLAAFVANRLRGKHKATFTPHVDDGDNVIVINADKIALTGKKYTDKKYYWHTGYIGGIKERTARQLLEGRFPERVVEKAVERMIPRGPLGRRQLKNLRVYAGSQHPHEAQQPESLDVGALNRKNKRIA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS5_VEREI
Sequence: MAKFQPKVQDEGRDDGLREKMIAVNRVTKVVKGGRILGFAALTVVGDGDGRVGMGKGKSKEVPAAVQKAMEEARRNMVKVSLKNGTIHHNVTGHHGAAVVMMAPAPKGAGIIAGGPMRAVFEVLGVTDIVAKSHGSSNPYNMVRATFDALVHSTTASQVAAKRGKTVEDIFA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: AROQ_CORGB
Sequence: MLGKILLLNGPNLNMLGKREPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELIDALHNARGTHIGCVINPGGLTHTSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLAAVSVIAGAGIQGYRFAVDILANLKK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: SSS1_SCYCA
Sequence: TKSRYRNRRSRPRRRYGRRMRKTRCRRKGRRISRRPRHTTYRRRVRKIVHLKRRSRPRDEIDNLKVKNNRRLNESLKQHRLPMRVPV
What is the function of this protein?
Involved in nuclear basic protein transition: histones are replaced by spermatid specific proteins which are themselves replaced by protamines in late spermatids.
What are the official names of this protein?
Spermatid-specific protein S1.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYR_PSEF5
Sequence: MKDTIRQLIQQAITQLVTEGVLPEGLTPAIQVENTRDKTHGDFASNIAMMLAKPAGMKPRDLAEKIIAALPAHEDLSKAEIAGPGFINFFQNTQALAARLDAALGDDHLGVRKAGPAQRTVIDMSAPNLAKEMHVGHLRSTIIGDGVARVLEFLGDTVIRQNHVGDWGTQFGMLMAYLEENPITSDELSDLENFYRAAKQRFDESEAFADRARGLVVKLQAGDPDCLELWTKFKDISLSHCQKIYELLNVKLTMADVMGESAYNDDLINVVNDLKAQGLLVESNGAQCVFLDEFKNAEGEPLPVIIVKADGGYLYATTDLAAVRYRSGKLKADRALYFVDQRQALHFQQVFAVARKAGFVTHPMEMEHMGFGTMNGADGRPFKTRDGGTVKLIDLLTEAEERAYALVKEKNPQLPEADLRSIAKVVGIDSVKYADLSKHRTSDYSFNFDLMLNFEGNTAPYLLYAYTRAAGVFRKLGKDFSEVGGQIELHAAQELELAAKLAQFGEILNNVAEKGTPHILCTYLYDVAGLFSSFYENCPILAAETPTQMHSRLRLTELTRRTLKQGLELLGLKVLEQM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XXLT1_HUMAN
Sequence: MGLLRGGLPCARAMARLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAPAAPSPPALELARGSVAPAPGAKAKSLEGGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDKLFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRHTFWQFRHENPQTRVGGPPPEGLPGFNSGVMLLNLEAMRQSPLYSRLLEPAQVQQLADKYHFRGHLGDQDFFTMIGMEHPKLFHVLDCTWNRQLCTWWRDHGYSDVFEAYFRCEGHVKIYHGNCNTPIPED
What is the function of this protein?
Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose (PubMed:22117070, PubMed:8982869).  Known targets include Notch proteins and coagulation factors, such as F9 (PubMed:22117070, PubMed:8982869).
What are the official names of this protein?
Xyloside xylosyltransferase 1, UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
Protein: UVRC_CLOBK
Sequence: MFDLEYQLKNLPDKPGVYLMKNNLGEIIYVGKAKILKNRVRQYFQKSQKHSEKVKAMVKNIEEFEYIITDSEIEALILECNLIKKYRPKYNILLKDDKHYPFIKVTLAEDFPRVVSTRKVTKDGSKYFGPYVDGSSVKDIIELIKKTFPIRTCKKNIVEGAKAIRPCLNYQIGLCKAPCAQYIKKSEYREIIDDVIKLLSGKHLDIVENFKLNMEKAAENLEFEKAAMLRDKINIIEKIGEKQKIILNNFDNEDYISLYSDGKDTCFQVFFLRNGKIVGREHFIIEDTFDTNSSTLISNFLKEFYGGTAYIPKTIYVPSIEDEALLEQWLTLKKESKSTIKIPIKGEKKNILVLVEKNAKTTLENFKLKYLQEKALYDNVLKDLKNILRLQEEPIRIEAFDISNIQGFDSVGSMVVFEKGRAKPSDYRRFKINTVKGADDYKSMKEILTRRFQHGLSEIKSIQDRKLEFSSGKFSVFPDLILMDGGKGQINIALEVLNTFNIDIPVCGMVKDNKHRTRGLIYNGEEIIINKYGSVMKFITRVQDEVHRFAISYHRSLRGKNSFHSLLDDIPNIGEKRKKDLLFNFKSIDNIKKATYEELLSIPSMDKKSAECVLEFFK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_THET2
Sequence: MRLVYGLGRSGLGVLRFLRKRGLPARFYDDRPREEEVREALALGFQPDWNLEEAYEEVVAAPGVPLDHPHLKRLAARGAKVLGEAELAYRLSPTPIVGITGTAGKTSTTLFTAHLLRAHGLRAREGGNVDPPLVSVVDEAEVAVAELSSFQLERVHAFRPRVAVLLNLGVDHLDRHGTVEAYHAAKLNLLKNLTPEDALVYNRLDPKVRRAAEASPARLYPFTPGSTPRETNLRAALEATRAYLDLLGRPLDPGAVAEALRTLPEAPHRFQAFARKGGVVFIDDSIATRTEAVRAALEAAPAPIAWILGGEDKGADLAPLLPLLGRVRVALALGRDGPRFARALEGRTEVVVIAEKDGRTAMRKAVEEALSRLEQGSVLLAPLAASFDQFRDYKDRAQAFREAVFALGGEPWTPSSS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPHS1_PICSI
Sequence: MAIVSSVPLASKSCLHKSLISSIHKLKPFCRTIPTLGMSRPGKYVMPSMSMSSPVSDDGVQRRTGGYHSNLWNDDIIQFLSTPYGEPAYRERGERLIDEVKNMFNSISMEDVEFSPLNDLIQRLWIVDSVERLGIDRHFKNEIKSTLDYVYSYWTQKGIGCGIESVVPDLNSTALGLRTLRLHGYPVSAEVLKHFQNQNGQFACSPSETEGEMRSIVNLYRASLIAFPGEKVMEEAEIFSTKYLKEALQKIPVSSLSREIGDVLEQDWHTNLPRLEARNYIDVFGQDTKDTKLYMKTEKLLELAKLEFNIFQSLQKTELDSLLRWWKDSGFPHITFSRHLHVEYYTLASCIAFEPQHSRFRLGFAKACHVITILDDMYDVFGTIDELELFTAQIKRWDPSATDCLPKYMKRMYMILYDMVNEMSREAETAQGRDTLNYARQAWEDFIDSYMQEAKWIATGYLPTFDEYFENGKVSSGHRVAALQPILTMDIPFPHDILKEVDFPSKLNDLASAILRLRGDTRCYKADRARGEEASCISCYMKDNPGATEEDALSHINAVISDVIKGLNWELLNPNSSVPISSKKHVFDVSRALHYGYKYRDGYSVSNIETKSLVMRTLLESVPF
What is the function of this protein?
Terpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens (PubMed:21385377).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to (-)-beta-phellandrene (PubMed:21385377).
What are the official names of this protein?
(-)-beta-phellandrene synthase 1, chloroplastic, Terpene synthase TPS-Phel-1, PsTPS-Phel-1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL35_ECO57
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: HEMH_GEODF
Sequence: MSEKTAVVLLQMGGPDSIAAVEPFLFNLFSDREIIKIGPALLQPFIARFICRRRAPKVEAYYEQIGGKSPIRELTEAQAKALETELGDGYRAFVAMRYWKPTTIDALAAIKREGISRVIALSLYPHYSRATAGSSINELKRVLGQAGVSFQVSYIDRFYDHPLYIKALAEKVEEGLSEFSDRSRVTLVFSAHSLPQSFIDDGDPYLSHIQATVRLVMERLGNIDYHLAFQSRAGPVKWLEPSTEEMMKRLATEGRKEMLMVPLSFVSDHIETLYEVDIQYAKEAKQLGIDKFRRSPSLNSSPLFIECLAELVKSVKGEG
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PALI_CANAL
Sequence: MFKAFIALLILLIVCWVIQLLPVIAVPFTTPDANIYLSYYNNYKFGVFGICNVERHICSKPSIGYPSTNSTFYAYDNDESFGTGGIVLPSDVRYTISKLLVVHVVAFCFSSLLLIVIFGLIIILFFKYIKTKKDLEGIQLNDSSHEITIHSDEEDNNNNNIDNTNHNNKRASVTINKTIFDLTPFLNLMLVFTFFSVLTTLLAFLADILLFTPNLSYLGWLQLIPIVSMALVTSMLCFIKRSISSRKFFESEYRYANDDMRIMRKTYVDEFWNDNASDDGFYVYTDGFYTRNGDNVQQPTSNTAGSLLSEHHDVSIVEPRTFLDTDDSRRGSSPHEFIELQNLRPV
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palI/RIM9.
What is the protein family that this protein belongs to?
Belongs to the palI/RIM9 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.