PharMolix/UniProtQA huggingface dataset:
Protein: ACADV_MOUSE
Sequence: MQSARMTPSVGRQLLRLGARSSRSTTVLQGQPRPISAQRLYAREATQAVLDKPETLSSDASTREKPARAESKSFAVGMFKGQLTIDQVFPYPSVLSEEQAQFLKELVGPVARFFEEVNDPAKNDALEKVEDDTLQGLKELGAFGLQVPSELGGLGLSNTQYARLAEIVGMHDLGVSVTLGAHQSIGFKGILLYGTKAQREKYLPRVASGQALAAFCLTEPSSGSDVASIRSSAIPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPIKDAATGAVKEKITAFVVERSFGGVTHGLPEKKMGIKASNTSEVYFDGVKVPSENVLGEVGDGFKVAVNILNNGRFGMAATLAGTMKSLIAKAVDHATNRTQFGDKIHNFGVIQEKLARMAILQYVTESMAYMLSANMDQGFKDFQIEAAISKIFCSEAAWKVADECIQIMGGMGFMKEPGVERVLRDIRIFRIFEGANDILRLFVALQGCMDKGKELTGLGNALKNPFGNVGLLMGEAGKQLRRRTGIGSGLSLSGIVHPELSRSGELAVQALDQFATVVEAKLVKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGYPTAQHEKMLCDSWCIEAATRIRENMASLQSSPQHQELFRNFRSISKAMVENGGLVTGNPLGI
What is the function of this protein?
Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats.  The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA.  Among the different mitochondrial acyl-CoA dehydrogenases, very long-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 12 to 24 carbons long primary chains.
What are the official names of this protein?
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial, MVLCAD, VLCAD.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: AL1L1_MOUSE
Sequence: MKIAVIGQSLFGQEVYCQLRKEGHEVVGVFTIPDKDGKADPLGLEAEKDGVPVFKFPRWRARGQALPEVVAKYQALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECDVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGTAPRRPQPEEGATYEGIQKKETAMINWDQPAEAIHNWIRGNDKVPGAWTEACGQKLTFFNSTLNTSGLVAQGEALPIPGAHRPGLVTKAGLILFGNDDRMLLVKNIQLEDGKMMPASQFFKGSASSALELTEEELATAEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMATTFGDFIQLLVRKLRGEDGESECVINYVEKAVKKLTLQMPYQLFIGGEFVDAEGAKTYSTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGLWGKINARDRGRLLYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDQFVQKVVEEVGKMKIGNPLDRDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQVPRPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRIKTVTFEY
What is the function of this protein?
Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:31624291).  May also have an NADP(+)-dependent aldehyde dehydrogenase activity towards formaldehyde, acetaldehyde, propionaldehyde, and benzaldehyde (By similarity).
What are the official names of this protein?
Cytosolic 10-formyltetrahydrofolate dehydrogenase, 10-FTHFDH, FDH, Aldehyde dehydrogenase family 1 member L1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ANIA_NEIMB
Sequence: MKRQALAAMIASLFALAACGGEPAAQAPAETPAAAAEAASSAAQTAAETPSGELPVIDAVTTHAPEVPPAIDRDYPAKVRVKMETVEKTMTMEDGVEYRYWTFDGDVPGRMIRVREGDTVEVEFSNNPSSTVPHNVDFHAATGQGGGAAATFTAPGRTSTFSFKALQPGLYIYHCAVAPVGMHIANGMYGLILVEPKEGLPKVDKEFYIVQGDFYTKGKKGAQGLQPFDMDKAVAEQPEYVVFNGHVGAIAGDNALKAKAGETVRMYVGNGGPNLVSSFHVIGEIFDKVYVEGGKLINENVQSTIVPAGGSAIVEFKVDIPGSYTLVDHSIFRAFNKGALGQLKVEGAENPEIMTQKLSDTAYAGNGAAPAASAPAASAPAASASEKSVY
What is the function of this protein?
Catalyzes the reduction of nitrite to nitric oxide (NO).  It could be essential for growth and survival in oxygen-depleted environments.
What are the official names of this protein?
Copper-containing nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: YCLI_BACSU
Sequence: MNFIKRAFWNMKAKKGKTLLQLFVFTVICVFVLSGLAIQSAAQKSSELARQELGGSVTLQVDRQKQMEKQQDSGEKRSFESTPIKVSDANKLAALDHVKSYNYTTSASANAGNFDAIESSSSSDSSSSSSSSNAKNSQGGGQGGPQMVQADLSIEGVISTALVDDFSDGDSKITDGRAITKSDVGKKVTVINETLAEENDLSVGDSITIESATDEDTTVKLKIVGIYKTTSSGDDQAQNFSFLNPYNKLYTPYTATAALKGDDYKNTIDSAVYYMDDAKNMDTFVKAAKKTSIDFDTYTLNTNDQLYQQMVGPIENVASFSKNVVYLVSVAGAVILGLIVMMSIRERKYEMGVLMAIGEKRWKLIGQFLTEILIVAVIAIGLASVTGNLVANQLGNQLLSQQISSSTDSTQTASGQMPGGGGGMGGKMFGHSSSNVDVIDSLNVAVSMNDMLILGGIGILIAIIATLLPSISVLRLHPKTILTKQE
What are the official names of this protein?
Uncharacterized ABC transporter permease YclI.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FDHE_PECAS
Sequence: MSIRIVPQEQLEQNEQSTREGHIPPLLFANLKSLYSSRAERLRQLAEDHPLGDYLTFAAGVVEAQQKVLHDHPLHLDLSDVLKQSGERPPLDIAVFPRDAHWHTLLRALIEELKPDASGQVLSTLENLEKASEQELEEQATALLQHEFRAENNDKAPFIWAALSLFWAQMAGLLPGKARAVPGEHRQFCPVCGSIPVSGVVQLGTSSGLRYLHCNLCESEWHMVRVKCSNCEESSELNYWSLDSENSAIKAESCGHCGTYVKLLYQEKDHRVEAVADDLASLVLDVKMEEEGFSRSSINPFLFPESSIE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFBA_METJA
Sequence: MEALVLVGHGSRLPYSKELLVKLAEKVKERNLFPIVEIGLMEFSEPTIPQAVKKAIEQGAKRIIVVPVFLAHGIHTTRDIPRLLGLIEDNHEHHHEHSHHHHHHHHHEHEKLEIPEDVEIIYREPIGADDRIVDIIIDRAFGR
What is the function of this protein?
Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis.  Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation.  Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni-sirohydrochlorin.
What are the official names of this protein?
Sirohydrochlorin cobaltochelatase, CbiXS, Sirohydrochlorin nickelchelatase.
What is the protein family that this protein belongs to?
Belongs to the CbiX family. CbiXS subfamily.
Protein: HBB_LEONI
Sequence: VHLTGEEKSAVTTLWGKVNVEEVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMNNPKVKAHGKKVLGAFSDGLAHLDNLKGTFAQLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RIBB_YERPA
Sequence: MNQTLLSDFGTPVERVERAIDALRNGRGVMVLDDESRENEGDMVFAAEAMTLEQMALTIRHGSGIVCLCITDERRQQLDLPMMVTHNSSQFQTAFTVTIEAAEGVTTGVSAADRLTTIRKAIADNAKPADLNRPGHVFPLRGQPGGVLSRRGHTEASIDLATLAGYKPAGVLCELTNDDGSMAHAPEVIAFAKLHDMPVVTIDDLAAYLQSRAKKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: ITPA_COPC7
Sequence: MASKPLVFVTGNANKLKEVKYILFQGGNPIEIENQAVDLPEIQGTTTEVARDKCRRAAEALGTACITEDTALGFNALKGLPGPYIKYFLEALGHEGLNKMLAGFEDKTADAICTFAYSAGPGTEPIIFEGRTPGKIVPARGPGIFGWDAVFEPIEGNGLTYAEMPPEEKNKISHRYRALDKLRDFLQAEANKSQNS
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PETN_WHEAT
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: OPGG_DICD3
Sequence: MLVNKFRVKQRVANLRWVSAAVMLSLTSLHAWAFSIDDVAQKAEKLAEKGYEAPKSNLPAQFRDMKFADYQQIRFNQDKSYWNSDQTPFKLQFYHQGMYFDIPVKINEVTATEVNEIKYSTDYFNFGSVNHDPATVKDLGFAGFKVLYPINKADKHDEILSMLGASYFRVVGKGQVYGLSARGLAIDTALPSGEEFPRFREFWIEHPKPEDKHLVIYALLDSPRSVGAYRFVLYPGSDSMMDVEAKVYLRDKVGKLGVAPLTSMFLFGPNQPSPTLNYRPALHDSNGLSIHAGNGEWIWRPLNNPKHLAVSTYTIENPKGFGLLQRGRDFSGYEDLDDRYDLRPSGWIETKGDWGKGKVELVEIPTADETNDNIVAFWTPENLPEKGKPLEVKYRLHFTKDEEALHSPEQAYVMQTMRSTGDVKQSNLIRQPDGTTAFLVDFVGGKLKDLDPNTPIASQASIGDNGEIVENSVRYNPVTHGWRLTLRMKVKDNKQPTEMRAALVNGETTLTETWSYQLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).  Seems to be required for pathogenicity.
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YL344_MIMIV
Sequence: MDPNSIEIELSDDDRVISFHANRQNLINISEYFKILLTKFNLHDKQQIPIKVPNAFVAYDIIVELTENTESNVGNLPVWEHYLEKLKFMDYVGLSAKMIRSIDTTNIVVPKSNFESLIKLYEQLGYNSSLIPLIKNSFQKDNTNILIEPHVAKKLLNVSESKIIHAGYTRGGLHVINYCDYIDRKIIHTFDKHNDFISFLSYSKWNHDASMEQYINSIAISPNKKYIALATTCGLIIYNLIDKTHHDTIQTNQNINFVDFNYSSTNIFYRKRKWIGANGSNKVGIYNLETSKEISIGIDNLRNYHSKLSSTGTDLCILSKNLLVMCDNFNRIVVINYALDKIIKILDSCIYLKNNDNTNTVFLFPSSNKKYLGHLIVNYKKIYVQKSDTYTLFVYYIDSKRQDLQYVIEYTGSAPVHIDISNKLVVIGDCTGFFSIYKYKSGKIVFRNKIKSHNSCVTSIAISSNNKMILTAGLDGLLKLWNSKTLNLIDSYYHGCEYVDFISFTSEFGLDFDNFLRKSISNKSIQ
What are the official names of this protein?
Uncharacterized WD repeat-containing protein L344.
Protein: Y384_PICTO
Sequence: MSGIVTYGSYIPRYRIRPEEIARVWGEDPEKMKNGIFILSKSVPGPDEDVATISVEAARNALKRSNIDPNDIGAIYIGSESHPYAVKPTATIVAAAIGMPFRTFAADYEFACKAGTAAMQNIKAMVDSNMIKYGMAIGSDTSQGAPGDALEYTASAGGTAMVIGRDNVIAEINKTISVATDTPDFWRREGEPYPKHGERFTGEPGYFKHVIGAARDIMSELNTKPDDYDYVVFHQPNGKFPTRAAKILGFREEQYREGLITPYIGNTYSGSTMTGLSAILDVSRPGDRILAVSFGSGAGSDAFDITVTDNILDYHRENAPGVRKMMESTEYIDYAVYSKFRKILVFGDNLE
What are the official names of this protein?
UPF0219 protein PTO0384.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. UPF0219 family.
Protein: WNT10_XENLA
Sequence: QECKCHGTSGSCQFKTCWYVTPDFRAVSTLMRDKLQRAVFVNSRNKNSGAFHPRLNKKRLQRELVYFEKSPDFCEKDPRVDSLGTQGRVCNKTSQQMDNCASLCCGRGHNVLMQTRRERCNCRFHWCC
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-10, XWnt-10.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: FAEC_ASPFU
Sequence: MVPTIIYSAILALSAFTPSVFAQTRSSGCGKQPSLANGVHNINGREYILKVPDNYDKNKAHHLVFGLHWRGGNMWNIVDGQSIQPWYGLETRAQGSAIFVAPNGKNAGWANYGGEDIAFIDAIIKQVESDLCVDQSSRFATGFSWGGGMSYSLACSRAKQFKAVSVLSGGVISGCDGGNDPIAYLGIHGINDGVLPFQGGVNLAQKFVRNNGCQQSNVGTPQPGSRGSVRTDFKGCSKPVSFIAYDGGHDAAPLGVGSSLAPDATWRFFMAA
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin.  Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan (By similarity).
What are the official names of this protein?
Probable feruloyl esterase C, Ferulic acid esterase C.
What is the protein family that this protein belongs to?
Belongs to the faeC family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIC_MYCA9
Sequence: MSTPSSRSQAPETVTTGPIQGSEKIYQELPNGLRVPQRRVNLTNGEYLDLYDTSGPYTDTNAVIDLHKGLPPRAGIVTDRGTQLQRARAGEITAEMEFIAVREGVPAELVRTEVAAGRAVIPANHKHPESEPMIIGKAFGVKINANIGNSAVTSSIAEEVEKMVWAIRWGADNIMDLSTGKDIHQTREWILRNSPVPVGTVPIYQALEKTNGDPAALTWELYRDTVIEQAEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFEELCEILARYDVTFSLGDGLRPGSIADANDEAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVKLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHSADLAKGHPRAQLRDNALSKARFEFRWEDQFNLSLDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMRITADIREFAAENGLETQEDIDAMLARGMEEKSAEFAEHGNRVYLPIA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ASTB_ECO27
Sequence: MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQGLLKMKKLADAGFPQAVIPPHERPFIPVLRQLGFRGSDEQVLEKVARQAPHWLSSVSSASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFSVHSALPQVALLGDEGAANHNRLGGHYGEPGMQIFVYGREEGNDTRPSRYPARQTREASEAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNCQVLFCHQQAFARQSQLLANLRARVNGFMAIEVPATHVSVSDAVSTYLFNSQLLSSDDGSMMLVLPQECREHAGVWGYLNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFNALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: RL16_GEOTN
Sequence: MLMPKRVKYRREHRGRMKGRAKGGTEVHFGEFGLQALESAWITNRQIEAARRAMTRYMKRGGKVWIRIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKVMFEVAGVSEEVAREALRLASHKLPIKCKFVKREETGGEA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: LMF2_XENLA
Sequence: MGEHRLARSAFLWGLSGIYLFAFVSLYVQIPGLYGREGILPAWKMLRFTGKGFWEQMKDSPSLLWFGPRLGLDTEMTMELICLLGALLSLGALLFSCLRDSLVFLLLWVFYLSLYQVGQVFLYFQWDSLLLETGFLAILVAPLHAMRWKTSVWSAHDGVTFWLTRWLLFRLMFASGVVKLTSRCPTWWGLTALTYHYETQCIPNPAAWYAHQLPVWLQKFSVVATFFIEIGVPWLFFLPFRRLRLFSFYSQVLLQILIIITGNYNFFNLLTIVLCCSMLDDQHIAFFQRHKKTQHKGGIATSAFSLRSLVSLLEIPIFGLLVFWTVKYFDLQINWDKHSLESRTAFTYHDFQQWLRTITFPSIWIAAASLGWEILKGMYRSASVRGFFWKLWSTLQWLMFSCAAAAMFTISLVPYTYMDFESNGQLWPEVHQMFNTVDRYQLVNSYGLFRRMTGVGGRPEVVVEGSFDRETWTEIEFMYKPGNISTIPTVIVPHQPRLDWQMWFAALSHHSHSPWFASFVYRLLQGNKDVIHLVQNDESLYPFHANPPTYIRAQQYKYWFTEVDQSGHMPKSWWRRRHVEEFFPAVFLDDPFLDNLLSQHGLKDKPPARRSLDAPIPFVLKLIRDFLHPLPAPLLLHSFIFGIFTIYFLQAMFGGVSRPSVAKQRHSMPPNEKKKQKPNSGQGESASSKSSGHGTDTVRRNKKNEKS
What is the function of this protein?
Involved in the maturation of specific proteins in the endoplasmic reticulum.
What are the official names of this protein?
Lipase maturation factor 2.
What is the protein family that this protein belongs to?
Belongs to the lipase maturation factor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: METN1_BURL3
Sequence: MIELRNLSQRFPGPGGWVEALRNINLTIPQGEVFGIIGRSGAGKSTLVRTINLLTRPTEGNVVVGGRDLTMLPAGALREARREIGMIFQHFNLLSSRTVFDNVALPLELAGASRAEIDAAVLPLLDLVGLSAQKDRYPSQISGGQKQRVGIARALASQPKVLLSDEATSALDPETTRSILDLLKRINRELGLTIVLITHQMEVIKQVCDRVAVLDAGRVVEEGRVIDVFLQPHHEVTRALIGDVIAQELPPALKARVAERLKTGRGHLLRLAFTGSGVDQPILSETIRRYELDFNILHGQIDEIQGQAFGSLAVLAGGEPGKVGQALAFLREQGVVVEELSYVE
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL17_HAEIG
Sequence: MRHRKSGRQLNRNSSHRQAMFRNLASALVSHEIIKTTLPKAKELRRVVEPLITLAKVDSVANRRLAFARTRNVETVAKLFNELGPRFAQRAGGYTRILKCGFRAGDNAPMAYIELVDRPEVAEATTEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MSCL_ANASK
Sequence: MSFASEFKAFALKGNVVDLAVGVIIGAAFGKIVDSIVNDLVMPVVGAIFGGLDFKDYFVALKEIPPGVPHALDAVKKAGVPVFAYGSFLTIVLNFLILAFIIFLMVKQFNRMKRAEPAPAPAAPPEQVVLLREIRDALRR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOC1_ASPCL
Sequence: MAPNKPSVKGKSSSKGDSKTGKPLSSASKVNKKNVKRPPPKEVKSKARTESSLLKKTKKREYTEEELGLPKLNMITPVGVVKPKGKKKGKVFVDDQEGMMTILAMVNAEQEGHIESKLQKARQMEEIREARRKEAEARLAQKKSKLDDAKESIRQKKKRKGGSSEDSAADTSAAASGAKSKGKRKSVSFA
What is the function of this protein?
Required for efficient assembly and nuclear export of the 60S ribosomal subunit.
What are the official names of this protein?
60S ribosomal subunit assembly/export protein loc1.
What is the protein family that this protein belongs to?
Belongs to the LOC1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y1794_ALIF1
Sequence: MDMTNAQRLILSNQYYLMSQMDPTNAEKYKRQQLIVERGYELQIRELDKDFGCITETECREIIDFMEMYHAMQESYNMLSEECQAKVDARRLQFLGFDIATEAQQVNYVRFLTSSEGLYPQFDKADHHFNSQMPMLDKYRRMLTTWRNCPRQYHLCSTELAQIFNA
What are the official names of this protein?
UPF0304 protein VF_1794.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: POP8_YEAST
Sequence: MGKKTFREWQYFKLSITSFDQDVDDAHAIDQMTWRQWLNNALKRSYGIFGEGVEYSFLHVDDKLAYIRVNHADKDTFSSSISTYISTDELVGSPLTVSILQESSSLRLLEVTDDDRLWLKKVMEEEEQDCKCI
What is the function of this protein?
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.  Also a component of RNase MRP, which cleaves pre-rRNA sequences.
What are the official names of this protein?
Ribonucleases P/MRP protein subunit POP8, RNA-processing protein POP8, RNases P/MRP 15.5 kDa subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: YNFB_SALCH
Sequence: MNNTLSKRLCLTAMLTLAAVVYTTSAFAETSKLVIESGDSAQSRQEAAMEKEQWNDTRSLRQKVNTRAEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVITP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: Y1960_HAEIG
Sequence: MFSLKRQQGASFEHQARLFLESKGLTFIAANQNFKCGELDLIMNDKETIVFVEVRQRSHSAYGSAIESVDWRKQQKWLDAANLWLAKQNMSLEDANCRFDLIAFGKTPQDIQWIPNFLD
What are the official names of this protein?
UPF0102 protein CGSHiGG_01960.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: GP161_DANRE
Sequence: MNGSKNGTAVANSTNGLDDNGLMVLESVSIIIIAILACLGNLVIVVTLYKKPYLLTPSNKFVFSLTSSNLLLSVLMLPFVVASSVRRDWMFGVVWCNFTALLHLLVSSSSMLTLGAIAIDRYYAVLYPMIYPMKITGNRAVLAIVYIWLHSLVGCLPPLFGWSSFEFDRFKWTCTVSWHKEISYTAFWVTWCCLLPLVAMLVCYGVIFRVARIKARKVYCGSVVVSQEESSSQNNGRKNSNTSTSSSGSRKSLIYSGSQCKAFITILVVLGTFLTTWGPYVVVISTEALLGKNSVSPQVETLVSWLSFTSAVCHPLIYGLWNKTVRKELLGMCFDDRYYRESFVIRHRTSRLFSISNRITDLGMSPHLTAMLVGGGQLLGRGSSTGDTGFSYTQDSATDVMLLESYTSEASHSAHCTANKRRSSVTFEDQVDHIPQGDPSVVQVTADIHKSLDSFASSLAKAIENDAKLQLLGEWTQIPTSLFTVRNTQRVPRYLDGQRLRMESIDEGIVKDDDDDEEEMEREEKM
What is the function of this protein?
Key negative regulator of Shh signaling during neural tube development.  Recruited to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of gli3 into gli3r and repress the Shh signaling.  In presence of shh, it is removed from primary cilia, preventing its activity and allowing activation of the Shh signaling (By similarity).  Required in left/right patterning by modulating Ca(2+) levels in the cells surrounding the Kupffer vesicle.
What are the official names of this protein?
G-protein coupled receptor 161.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Mainly localizes to primary cilium and is removed from primary cilia in presence of shh.
Protein: GLIP6_ARATH
Sequence: MSSSSSMDLLMCLLLLISPVVLAKSSSTVPAIFTFGDSIFDAGNNHYNKNCTAQADFPPYGSSFFHRPTGRFTNGRTVADFISEFVGLPLQKPFLELQIQILNGTSNFSNGINFASAGSGLLLDTNKFMGVTPIQTQLQQFQTLVEQNLIEKSIIQESLFLLETGSNDIFNYFLPFRAPTLSPDAYVNAMLDQVNKTIDQIYKLGARRIAFFSLGPVGCVPARAMLPNAPTNKCFGKMNVMAKMYNKRLEDIVNIIPTKYPGAIAVFGAVYGITHRFQTYPARYGFSDVSNACCGNGTLGGLMQCGREGYKICNNPNEFLFWDFYHPTEHTYRLMSKALWNGNKNHIRPFNLMALATNKITF
What are the official names of this protein?
GDSL esterase/lipase 6, Extracellular lipase 6.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYT_POLAQ
Sequence: MPVVTLPDGSKREYEAPVRVADVAQSIGSGLAKAALGGIVDGQMVDTSFVIDKDSHLAIITDKSPEALEIVRHSTAHLLAYAVKELFPEAQVTIGPVIENGFYYDFSYHRPFTPDDLVALEKKMTELAKKDEPVVRTVMPRDEAVEFFKQQGENYKAELIASIPQGEDVSLYAEGKFTDLCRGPHVPSTGKLKVFKLMKLAGAYWRGDSKNEMLQRIYGTAWLRKEDQDAYLHMLEESEKRDHRRLGKQLDLFHFQEEAPGLIFWHPKGWSIWQEVEQYMRRVYQNEGYQEVKAPQILDRGLWEKSGHWDNYKENMFTTESENRAYALKPMNCPGHVQIYNSGLHSYRELPLRFGEFGQCHRNEPSGALHGLMRVRGFTQDDGHIFCTEDQIQSEVAAFDKAVRAVYQDFGFTEVAVKLALRPAKRVGDDAIWDKAEDALRGALKASGQEWEELPGEGAFYGPKIEYHLKDSIGRTWQCGTIQVDFSMPARLGAEYVAEDNSRKTPVMLHRAIVGSLERFIGILIENHAGNMPVWLAPTQAVVLNISGNSAAYAQKVQQSLKKQGFRVESDLRNEKITYKIREHALQKIPFLLVVGDKESESNTVAVRARGGVDLGVMPLDAFVARLQQDISQKVGPEPS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.