PharMolix/UniProtQA huggingface dataset:
Protein: DUSTY_DANRE
Sequence: MENPQKPRELTRAFNHYNKHSGFLKKNLKETILFFREIRQNHSNTCAAAEPGQLSCISFPRQDEEYLQNVVSSAPYILILGQDCSARYQLLNCLLGERLLPLGPEAGGACGAEGGACRRRKLCFTHGRQTRLSLALPGQYELVHQLAAHCGRWDTVPRQDLEIQECEDPAQRLAELEITLHHTLLQEVKIMVLPCRNVQPLEEALEDCKRGILPIVLYAVSRESLSAQQLEDLQTLRESLPFPVCFIRVSDGGGGGALFTQLASLQLISASAGNCACGAPAAQSAGRMQGVLCDSLERLQRVLVPFTRQVLQNQQVEAATLLNTIHCRCLDLFIIQAFDMQRDLQITPRRLEYTREKEGELFCSLMAIANRKQEEMKEMIVETLSSMKEQLLEDAQNLDFTDIIMSSNGEPVSSKDIKVCISQIQDLIVNRLNQAVANKLTNSVDYLRESFVGTLERCLGSLEKSTPESCAHNVTSNHLKQILNAAYHVEVTFHSGSSVTRLFWEQIKQIIHRITWVNPPAITAEWKRKVAQDAIESLSAAKLAKSICSQFRTRLNSSHEAFAASLRQLEEGHTGRLERTEDLWLRVRKDHAPRLARLSLESRSLRDILLHGKPKLGRELGRGQYGVVYLCDSWAGRHPCALKSVVPPDDKHWNDLALEFHYTRSLPKHERLVNLHGSVIDHSYSGGSSIAVLLIMERLHRDLYTGLKAGLSLKERLLIALDVVEGIRFLHSQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYLCSGSVKLPEAFEKCASKDQLWTNVKKGCRPERLPVFDEECWQLMEACWNGDPSQRPLLGIVQPGLQSIMERLCGEKSLEDSN
What is the function of this protein?
May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation.  May induce both caspase-dependent apoptosis and caspase-independent cell death (By similarity).  Plays a role in the embryonic development.
What are the official names of this protein?
Dual serine/threonine and tyrosine protein kinase, Dusty protein kinase, Dusty PK, Receptor-interacting serine/threonine-protein kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Apical cell membrane. Basolateral cell membrane. Cell junction.
Protein: MURI_ECOBW
Sequence: MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLLPDLHYIYAFDNVAFPYGEKSEAFIVERVVAIVTAVQERYPLALAVVACNTASTVSLPALREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEMLGSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPGAEQLLPVLQRYGFETLEKLAVLG
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: TRHO_RICB8
Sequence: MSEKIAILSAYSFVNIEEPESLIPKLLFVGKRKYVKGTILLSKEGFNGSFSGSYESVNLVLEELKKLTNTKDVNVKINYSEIHPFQKLKVRLKKEIVAMNVDNLNVNLFKGEYIETKDWDEFITKQDVIVVDTRNDYEVEVGTFKAAINPYTETFKQFPAWAEQNAELLKGKKIAMFCTGGIRCEKSTSLLKSMGHEEVYHLKGGILQYLEDTQNKNNLWQGECFVFDDRRAVADDLAPAEGYWLERK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: CCNE_CAEBR
Sequence: MAGRKSSRTTGEPVKKAERKSAILSPHDELRERLLETSLDVKENIPERSSSTRNESVGSQRSDCSESRKRRSTEKGPVAKRPSTEKKGNGSRDDSFSSVFSEDRETESSVGSTSSRTRGQPLPAMPEEEESLDGSSDHNAESEESRETPQSDEHDGFEEDGDVEDDVSSDVNDEEDEYDEYEEDEETEDEFDLPLQNDDFAVTKRLMNDRHMIDAPSLLSYGKCEGIGSPTKVWSLMVKRDDIPRATRQLLRNHPDMTINMRRVLVDWMMECCDVEKLHRETFHLAVDYADRFLESTREEVISENFQLVGTAALFIAAKYEEIYPPKCADLAALTDGAFSCDDICRMESIVAKDLKWSFGPITSVQWLSTYLQLLGTGKKNNDHFEEGNMYIPELLRSEYLRMVRILDYLLSDIDSFNFSYRTIAAAVLFVNYDPRSAVEKATGFIYEQLRNVIDYVTPICRAYDRFTQEHVPKDIIPDYAPAEDAHNIQVHIKHYEVDPYVEKERERRHRRGPNRRL
What is the function of this protein?
Essential for the control of the cell cycle at the G1/S (start) transition.  In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages.  In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase.  During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase.  During hypoderm development at early larval stages, controls syncytial fate of seam cell daughter cells.  Involved in the progression of cell division in the intestinal lineage in larvae, and in particular in endoreplication, a specific growth pathway in the intestinal epithelium, required for feeding and gut development in growing larvae.  By controlling the activity of translational repressor gld-1, regulates the pool of germline stem cells and the size of the mitotic zone by preventing entry into meiosis.  In addition, repression of expression by gld-1 prevents mitosis re-entry in meiotic germline cells.
What are the official names of this protein?
G1/S-specific cyclin-E.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin E subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Co-localizes with cdk-2, in the sperm centrioles before the first embryonic mitosis and then to the male and female nuclei upon entry into mitosis.
Protein: SYV_ECOL6
Sequence: MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDIYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIVDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_STRR6
Sequence: MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRRELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSKNAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAESKEDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CYB_GARIS
Sequence: SGSLLGMCLIVRIITGLFLAAHYTADTSLAFNSVAHTCRNVQFGWLIRNLHANGASLFFICIYLHIGRGLYYGSYLNKETWNIGVILLLALMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIAGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYSTKDVLGFALLLTPLIALALFSPNLLGDPENFTPANPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLIPLLHNSKLRSMTFRPLSQILFWALVANLLVLTWVGS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: OR2D3_HUMAN
Sequence: MCSFFLCQTGKQAKISMGEENQTFVSKFIFLGLSQDLQTQILLFILFLIIYLLTVLGNQLIIILIFLDSRLHTPMYFFLRNLSFADLCFSTSIVPQVLVHFLVKRKTISFYGCMTQIIVFLLVGCTECALLAVMSYDRYVAVCKPLYYSTIMTQRVCLWLSFRSWASGALVSLVDTSFTFHLPYWGQNIINHYFCEPPALLKLASIDTYSTEMAIFSMGVVILLAPVSLILGSYWNIISTVIQMQSGEGRLKAFSTCGSHLIVVVLFYGSGIFTYMRPNSKTTKELDKMISVFYTAVTPMLNPIIYSLRNKDVKGALRKLVGRKCFSHRQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2D3, Olfactory receptor OR11-89.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FGR_RAT
Sequence: MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDMGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLICKIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQT
What is the function of this protein?
Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors devoid of kinase activity and contributes to the regulation of immune responses, including neutrophil, monocyte, macrophage and mast cell functions, cytoskeleton remodeling in response to extracellular stimuli, phagocytosis, cell adhesion and migration.  Promotes mast cell degranulation, release of inflammatory cytokines and IgE-mediated anaphylaxis.  Acts downstream of receptors that bind the Fc region of immunoglobulins, such as MS4A2/FCER1B, FCER1G and FCGR2.  Acts downstream of ITGB1 and ITGB2, and regulates actin cytoskeleton reorganization, cell spreading and adhesion.  Depending on the context, activates or inhibits cellular responses.  Functions as negative regulator of ITGB2 signaling, phagocytosis and SYK activity in monocytes.  Required for normal ITGB1 and ITGB2 signaling, normal cell spreading and adhesion in neutrophils and macrophages.  Functions as positive regulator of cell migration and regulates cytoskeleton reorganization via RAC1 activation.  Phosphorylates SYK (in vitro) and promotes SYK-dependent activation of AKT1 and MAP kinase signaling.  Phosphorylates PLD2 in antigen-stimulated mast cells, leading to PLD2 activation and the production of the signaling molecules lysophosphatidic acid and diacylglycerol.  Promotes activation of PIK3R1.  Phosphorylates FASLG, and thereby regulates its ubiquitination and subsequent internalization.  Phosphorylates ABL1.  Promotes phosphorylation of CBL, CTTN, PIK3R1, PTK2/FAK1, PTK2B/PYK2 and VAV2 (By similarity).  Phosphorylates HCLS1 that has already been phosphorylated by SYK, but not unphosphorylated HCLS1.  Together with CLNK, it acts as a negative regulator of natural killer cell-activating receptors and inhibits interferon-gamma production (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase Fgr, Proto-oncogene c-Fgr, p55-Fgr.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Mitochondrion inner membrane. Mitochondrion intermembrane space. Note=Colocalizes with actin fibers at membrane ruffles (By similarity). Detected at plasma membrane lipid rafts. Detected in mitochondrial intermembrane space and at inner membranes.
Protein: UXUA_SHIB3
Sequence: MEQTWRWYGPNDLVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIVEDAGLVWSVVESIPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNSDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSR
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: RBFA_MYCPN
Sequence: MASYKKERLENDIIRLINRTVIHEIYNETVKTGHVTHVKLSDDLLHVTVYLDCYNREQIDRVVGAFNQAKGVFSRVLAHNLYLAKAVQIHFVKDKAIDNAMRIESIINSLKKSKPN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y713_STRPF
Sequence: MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADASASELFDEFVAMQEKIQEMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIERIVFAPLKDLVK
What are the official names of this protein?
UPF0342 protein MGAS10750_Spy0713.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: YBEY_POLNA
Sequence: MALNSLSLSLQFGKFPDAALHRAALPRHSVARWIRHALQSDAEITVRIVGAEEGQALNRDYRAKDYATNVLTFDYTQAPYVTADLVLCAPVVAKEAQDNQKTLQAHYAHLLVHGTLHAQGYDHETGEEDAEEMEALEIEILAGLGFDNPYR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA_TRYCO
Sequence: MTSDKNPYKTEQRMGAVKAVSGPVVIAENMGGSAMYELVQVGSFRLVGEIIRLEGDTATIQVYEETGGLTVGDPVYCTGKPLSLELGPGIMSEIFDGIQRPLDTIYRMVENVFIPRGVQVKSLNDQKQWDFKPCLKVGDLVSGGDIIGSVVENSLMYNHSIMIPPNVRGRVTSIVPSGNYTLQDDIIELEYNGTVKSLKLMHRWPVRTPRPVASKESGNHPLLTGQRVLDALFPSVQGGTCAIPGAFGCGKTVISQALSKFSNSDAVIYVGCGERGNEMAEVLMDFPTLTTVIDGREESIMKRTCLVANTSNMPVAAREASIYTGITLAEYYRDMGKHIAMMADSTSRWAEALREISGRLAEMPADGGYPAYLSARLASFYERAGRVTCIGGPKREGSVTIVGAVSPPGGDFSDPVTSATLGIVQVFWGLEKRLAQRKHFPSVNWLISYSKYLNALEPFFNTLDPDYMRLRSVAAEILQREEELQEIVQLVGKDSLSESDKIILETAKVIREEFLQQNAFTPYDKYCPPYKTCWMLRNIVAFYEESQRVVAESAGELKITWNYIREMIPHIYTGLTEMKFRDPQEGEEANVEFYRKQNEEIVSAFASLLQ
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: TIMP1_MACMU
Sequence: MAPFEPLASGILLLLWLIAPSRACTCVLPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQSLRTRMA
What is the function of this protein?
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor.  Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16.  Does not act on MMP14.  Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1.  Plays a role in integrin signaling (By similarity).
What are the official names of this protein?
Metalloproteinase inhibitor 1, Tissue inhibitor of metalloproteinases 1, TIMP-1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSB_ACIF2
Sequence: MSFCVLIPARLASTRLPRKVLLDVGGIPMIEQVRRRALESGAAQVVVAADHPEVVDCIRSYGGEALLTAAEHVCGTERLAEAARLLGLADDAIIVNLQGDEPGMTPALLHATAQLLLDHPQRQMATAAVPITHWDELADPHAVKLVLDAEGCARYFSRAPIPWDRSHFPLSSGQTLPQTPGIWWRHLGLYAYRNAFLQDYAAWSASPLEVIESLEQMRALERGVQIAVYCAAEAPAAGVDTAADLDRVRDLFP
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5513_ORYSI
Sequence: MADSGSDAPISNRPEEEVTVEKTPEMEAAAEEERLRYLEFVQQAAAQVLVLAAAAYAYAKQGAGPLRPGVDHVEGTVKAVVGPVYDRFHGVPLDLLKFLDRKVGESVQELDRRVPPVVKEAPGLARSAAAEVRQAGLVGTATGLAKSAIARAEPRARDLYTRYEPVAERKAAEAWAALNRLPLVPSVTRAVLPAAASLSARYNTAVADGAKRGSAVATYLPLVPTERLSRVFGYPLADAAASPAPEMQPIPSQ
What are the official names of this protein?
REF/SRPP-like protein OsI_017815.
What is the protein family that this protein belongs to?
Belongs to the REF/SRPP family.
Protein: PRS2_METTH
Sequence: MVKFNNIIYDPQVSDKKFPVQASDPEREAKLVVLQPVGYPFVCNLMEAPRIDAVNKELFEIYARDQWEGFRAAEGSYLFDQKLLPDYAFKIIRAHPDGSKITRNTSIILLENDREEFHEVRSSITMDDVIGQEDAKIKCRIIMKYLEDPDRFRDWAPRNVLFHGSPGTGKTMLAKSLANELKVPLYLIKATSLIGEHVGDGARQIHELYELASKTAPSVIFIDEMDAIGLDRRYQSLRGDVSEVVNALLTEMDGINQNWGVVTIGATNNPELLDKAIRSRFEEEIEFKLPDDEERKLMLEKYIETMPLKVDFPVDKLVKLTREMSGRDIKDRVLKTALHRAIAEDSESVRAEHIEYALKERKVSGEPKHMFA
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
What are the official names of this protein?
Putative 26S proteasome regulatory subunit homolog MTH_1011.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: GH101_STRPN
Sequence: MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSGSTANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAEEKPKEDKPAAAKPETPKTVTPEWQTVANKEQQGTVTIREEKGVRYNQLSSTAQNDNAGKPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTKNNVFVGYDKDGWFWEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVNDHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTIQSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAEYLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDESKLLSSISFLGNALVSVSSNQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLAAGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKELPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQNPFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIEKAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLAHGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWGHGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLLGGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYKWTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDANGKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKITLDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQGANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYTNKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGADVSNVTLTLSREAGDQATYFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEKHNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEYEAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGDTWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPTVAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADDFASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRGSGSNGNLRDVKLVVTDESGKEHTFTATDWPNNNKPKDIDFGKTIKAKKIVLTGTKTYGDGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQASMKYATDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDYKQEIARPETPEQILPATGESQSDTALILASVSLALSALFVVKTKKD
What is the function of this protein?
Involved in the breakdown of mucin-type O-linked glycans.  Specifically removes the T-antigen disaccharide (Gal-beta-1,3-GalNAc-alpha) from extracellular host glycoproteins.  Representative of a broadly important class of virulence factors.
What are the official names of this protein?
Endo-alpha-N-acetylgalactosaminidase, SpGH101.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 101 family. A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Has been shown to be localized at the cell surface.
Protein: NTPPA_RHOPS
Sequence: MLGRPKLVLASGSPRRLALLNQAGIEPDALRPADVDETPTKGELPRSCANRLARAKAEAALQSIQLDDDLRGAYLLAADTVVAVGRRILPKAELVDEASQCLRLLSGRNHRVYTAVCLVTPKGSFRQRLIETKVRFKRLSEEDIDGYVGSGEWRGKAGGYAVQGIAGSFVVKIVGSYTNIVGLPLYETVSLLGGEGFPIRFGWLNAS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_ECOL6
Sequence: MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAAFSLPHAAHADLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFPLHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLVAPDEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: HIS81_BACHK
Sequence: MRVKEQLLTLRAYVPGKNIEEVKREYGLSKIVKLASNENPFGCSARVTEALTSLASQYALYPDGHAFELRTKVAKHLGVKAEQLLFGSGLDEVIQMISRALLHEGTNVVMANPTFSQYHHHAVIEGAEVREVSLKDGIHDLDAMLQQVDDQTKIVWICNPNNPTGTYVEKQKLLSFLESVPKSALVIMDEAYYEYAGAEDYPQTLPLLEKYENLMVLRTFSKAYGLAAFRIGYAVGNTELIGQLEVARLPFNTSTVAQSVALAALEDQAFLQECVKKNEEGLHQYYAFCKEYNVFYYPSQTNFIFLKLGIPGNEAFERLMKKGYIVRSGAAFGIDDGIRITVGLKEENDEIIELLKELVNEQVQKEETYS
What are the official names of this protein?
Histidinol-phosphate aminotransferase 1, Imidazole acetol-phosphate transaminase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.