PharMolix/UniProtQA huggingface dataset:
Protein: UBL1_YEAST
Sequence: MSGENRAVVPIESNPEVFTNFAHKLGLKNEWAYFDIYSLTEPELLAFLPRPVKAIVLLFPINEDRKSSTSQQITSSYDVIWFKQSVKNACGLYAILHSLSNNQSLLEPGSDLDNFLKSQSDTSSSKNRFDDVTTDQFVLNVIKENVQTFSTGQSEAPEATADTNLHYITYVEENGGIFELDGRNLSGPLYLGKSDPTATDLIEQELVRVRVASYMENANEEDVLNFAMLGLGPNWE
What is the function of this protein?
Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins.  Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or RUB1.  Preferentially cleaves ubiquitin from peptides and small adducts.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase YUH1, UCH, Ubiquitin thioesterase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family.
Protein: SMAG1_HUMAN
Sequence: MMFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQNSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTSTILSGQAHHSPLKRSVSLTPPMNVPNQPLGHGWMSHEDLRARGPQCLPSDHAPLSPQSSVASSGSGGSEHLEDQTTARNTFQEEGSGMKDVPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLKSLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSPDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI
What is the function of this protein?
Acts as a translational repressor of SRE-containing messengers.
What are the official names of this protein?
Protein Smaug homolog 1, Smaug 1, hSmaug1, Sterile alpha motif domain-containing protein 4A, SAM domain-containing protein 4A.
What is the protein family that this protein belongs to?
Belongs to the SMAUG family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Synapse, synaptosome. Note=Enriched in synaptoneurosomes (By similarity). Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule- like foci with ELAVL1, TIA1 and TIAL1.
Protein: ARGC_SHEHH
Sequence: MKNIAIIGASGYTGAQISSLINAESTMSIQGLYVSENSLDKGKALSDLYPAYSHIDLCLTPLTDDAKQTIVATADAVVLATDHGVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYGFTHEYSQVLADAVYGLAEWNAPQIATSKMIAVPGCYPTASLIALKPVAHLLTDILPVINAVSGVTGAGRKAQLHTSFCEVSLTPYGVLGHRHQPEIATQLGQEVIFTPHLGNFKRGILATITVQLAAGTTASDIEKAYQCYDSAELITVKQNQFPKVDDVVQTANCHLGWKFDEQSGYLVIASAIDNLMKGAASQALQCIKIHFNASVNH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_DICT6
Sequence: MALTKEEKKQIIEKFRLNENDSGSPEVQIALLTERIKRLTEHLKVHKKDYHSRVGLLKMIGRRRKLLKYLQEKDFERYKKLIQELGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FENR_RICRO
Sequence: MHNTDVVIIGAGPVGLFAVFQAGMLGMKCHVIDAQEVIGGQCITLYPEKPIYDIPAYPKIVAEELIKQLALQAAPFNPIYHLNQQAIELNKQDDFFEIKTSKNTLIKSKVIIIAAGAGSFGPNKPPLANIEDFESKSVFYFINDKSKFAGKNIVIAGGGDSAVDWAISLSDIANKIYLVHRRDKFTAAPESVRQLRHIAETNKIELITGYQLNALDGNNSELQSVIVKDLQNNTRKLDANILLPFFGLKQDLGSLANWGLNVKLHHIEVDSSYYQTNIEGIYAIGDIAHYVGKLKLILTGFAEAASSLHHAYSRVFDGKALHFEYSTTKNTGKRSKSVTK
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: HSE1_YEAST
Sequence: MSSSAIKIRNALLKATDPKLRSDNWQYILDVCDLVKEDPEDNGQEVMSLIEKRLEQQDANVILRTLSLTVSLAENCGSRLRQEISSKNFTSLLYALIESHSVHITLKKAVTDVVKQLSDSFKDDPSLRAMGDLYDKIKRKAPYLVQPNVPEKHNMSTQADNSDDEELQKALKMSLFEYEKQKKLQEQEKESAEVLPQQQQQHQQQNQAPAHKIPAQTVVRRVRALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYVTPIVEPSKEEIEKEKNKEAIVFSQKTTIDQLHNSLNAASKTGNSNEVLQDPHIGDMYGSVTPLRPQVTRMLGKYAKEKEDMLSLRQVLANAERSYNQLMDRAANAHISPPVPGPALYAGMTHANNTPVMPPQRQSYQSNEYSPYPSNLPIQHPTNSANNTPQYGYDLGYSVVSQPPPGYEQ
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
What are the official names of this protein?
Class E vacuolar protein-sorting machinery protein HSE1.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GPDA_LISMH
Sequence: MTQKKVAILGAGSWGTGLALVLADNNHKPVIWGNLDKIVNEINESHTNSHYLPDIILPTEVKATLSLDEAIDGAEIVVIAIPTNAMRIVCKQLNEALKEPTILVHVSKGIEPETNLRMSEVIEEEIDAAKRKALVVLSGPSHAEEVALRHPTTLCASCKDLTAAEIVQDRFINNNLRIYTNDDVIGAEIGGALKNIIALGAGISDGLGYGDNAKAALMTRGMAEITRLGVAVGSNPQTFYGLTGIGDLIVTCTSVHSRNWRAGNMLGKGENLDEVLEKMGMVVEGVRTAKAVHGWAKKLDIDMPITESIYAILFENKDAREAVDLLMGRKKKIEKESF
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_SYNC1
Sequence: MKCPFCGFADTRVIDSRLGKEGNNIRRRRECSQCERRFTTFERVEDMLPLIIKKDARRQPFDRKKVIGGIQRACEKRPVSIATIEKIVDTLERQLQESGEREIESKIIGQAVMDALHDLDQVAYVRFASVYRQFKDINEFMAELKDILAEGGNVRDN
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: YMM2_YEAST
Sequence: MPRNDSNQYYARWCCYRRPIRAAFARKGPFNSSSGYEENVARLKNTRSSHCRTARCQFNSSTWTCYFQHVGRKLATAIDYGSPQSIEISEIGAVMHQMSCERLSLSLFSRFACLLARLKTCVLLIN
What are the official names of this protein?
Uncharacterized protein YML122C.
Protein: TATA_CAMLR
Sequence: MHMPSGTQWLIILLIVVLLFGAKKIPELAKGLGKGIKTFKDEMNTEDDKKITQEDAQKIEKINEKDILAKENNEEVKKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ISPE_XANP2
Sequence: MELMRARAPAKINLTLRIEGRRADGFHDLASLVAFAGAGDLVFLHPDAPLALEVCGPTAAAAGPDDDNLVLRAARAFAERVPGARLGRFVLEKRLPVAAGLGGGSSDAAAALRLLAGLNGLALDDPRLFAAARATGSDVPVCLDPRARLMRGVGDVLSAPLALPPLSAVLVNCRVAVPTAGVFRALGLAPGAALAGPEHPAGLPETTMGNAAAVCAFLSGLPNDLEPPALALAPEIGRAMALLSEAPEARLVRMSGSGATVFALTDSCRTAASLARRLLAQQPGWWVKPTLLR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: HIS7_PHOLL
Sequence: MNQKLLFIDRDGTLITEPPTDFQVDRLDKLALETEVIPALLALQKSGFRLIMITNQDGLGTDSFPLEQFEPPHNLMMQIFSSQGIHFDEVLICPHKPEENCHCRKPKIKLVEKYLTEGLMDTANSYVIGDRETDLQLAKNMGIQGLHYHPKNLGWFAICEQLTRQDRHAHVQRITKETSINIDVWLDHEGSSDINTGVGFFDHMLDQIATHGGFRMHVQVKGDLCIDDHHTVEDTGLALGEALKLALGDKRGICRFGFVLPMDECLARCALDISGRPHLEYKAEFKHQRVGDLSTEMIEHFFRSLSYAMACTLHLKTKGSNDHHRAESLFKAFGRTLRQAIRVEGDTLPSSKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHRR_RAT
Sequence: MMIPSGECTYAGRKRRKPIQKRRLTMGTEKSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSYLRVKSFFQALQETCVWSAPALSPEDHSSRGFPVQEGRLLLESLNGFALVVSAEGMIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADTDNTVLGKLLRAQEGGKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPSGTALPPRLSLFCIVAPVLPSVTEMKMKSAFLKAKHRADIVVTMDSRAKAVTSLCESELHPKLNYLAGRSNGENVISLFRGQTDRSHWTRALARSSCLCLRGGPDLLDPKGTSGDREEDDQKHILRRSPGARGQREMHKYSYGLETPVHLRHLDWSTEQRSQEGTTKLTRQPSKSEPSTCLVPHGSCVPYPGSQGMFSASNMASFRESLDHPTGTYCSQMNRPLPDIHQGQVDPSTCHIPQGSLGSRIPLSGMQCFTARGFSTEDAKLPSLPVNIGTPCNPVLSLEVPIKMENESGSQDIVEASTTSCVWLGTGDMTRRHLVGFPARMHLKTEPDYRQQVCTPHRGHGILGTNPHSRDTVGSCREHAPLYSAHCTCLSPEPPHHLFMCSHSESQHPSLDQDCRAPIVKREPLDSPSWAAPGHVTVPRMFPKNASITVIPSKGSDGIFLP
What is the function of this protein?
Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation.  Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes.  Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5.  Autoregulates its expression by associating with its own XRE site.
What are the official names of this protein?
Aryl hydrocarbon receptor repressor, AhR repressor, AhRR.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly in the nuclear compartment. First cytoplasmic, translocates into the nuclear compartment upon interaction with ARNT in the cytoplasmic compartment (By similarity).
Protein: RS12_SACS2
Sequence: MVKSKSPKGIYAARKLRLKRLKFRRSQRKYKTKILKLKEKYDPLGGAPMARGIVLEKVGIESRQPNSAVRKCVRVQLVRNGRVVTAFVPGDGGVNFIDEHDEVIITGIGGTLGRSMGDLPGVRYKVIMVNGVSLDALYKGKKQKPVR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: BETA_STAHJ
Sequence: MSKKNSYDYVIIGGGSAGSVLGNRLTEDKDKEVLVLEAGRSDYPWDLFIQMPAALMFPSGNRFYDWIYQTEEEPHMGRKVDHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMESWDFAHCLPYFKRLEKTYGATPFDQFRGHHGPIKLKRGPATNPLFKSFFDAGVEAGYHKTKDVNGYRQEGFGPFDSQVHNGRRVSASRAYLHPAMKRKNLTVKTRAFVTKIHFDGNKATGVTFKRNGRYHTVDAGEVILSGGAFNTPQLLQLSGIGDAEFLKSKGIEPRMHLPGVGENFEDHLEVYIQHECKEPVSLQPSLDVKRMPWIGLQWIFARKGAAASNHFEGGAFVRSNNQVAYPNLMFHFLPIAVRYDGQKAPVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIVFNYLSTKEDEQEWVEAIRVARNILAQKAMDPYNGGEISPGPSVQTDEEILDWVRRDGETALHPSCSAKMGPASDPMSVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGKKPLEPQYVDYYKHGVSDENAGAMEFDPYYQH
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: ATPB_ALKOO
Sequence: MAEGNVGKLVQIIGPVIDIRFSRENLPNLLNAIEIEGPDGKIVVEVSQHIGDDTVRCVAMKSTDGLVRGMEAKDTGGPITVPVGRATLGRIFNVIGEPVDEKGAVAAEAKAPIHRPAPSFEDQATSTEILETGIKVVDLIAPYLKGGKIGLFGGAGVGKTVLIMELINNIAKEHGGLSVFSGVGERTREGNDLYNEMIESGVIDKTALVYGQMNEPPGARMRVGLTGLTMAEHFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTRKGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRQIVELGIYPAVDPLDSNSRVLDPAIVGDEHYSVARGVQEVLQRYKELQDIIAILGMDELSDEDKLTVSRARKIQRFLSQPFSVAEQFTGMAGKYVPLKETIRGFKEILEGKHDDIPESAFLFVGSIDEAVEKAKGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYT_SYNC1
Sequence: MVMIQIELPDGSIKEFSETTTPGDIAAGIGSGLARQAVAARFNDRMVDLCTPITESGRLEIITLNSPQGLEVYRHTAAHLMAHAVKDLYGDRVQVTIGPAVENGFYYDFYCEDHAFSPDDFEKIEKRMQELVKANLPIEREEVSRDSAIALFRELGEHYKVELIEDLDAPTVSLYRQGDFVDLCRGPHLPSTGRIKAFKLTSVAGAYWRGSEKNAMLQRIYATAFPDKKELRTYLNKLEEARKRDHRRIGRELDLFSFSEEAGAGLVIWHPKGALLRTLLEDFERREHLRRGYDIVMGPQILRTDLWKTSGHFDNYRENMYFTDVDGQGYGIKPMNCLAHMLIYKARQRSYRDLPLRYFELGTVHRHEKSGVLHGLLRVRGFTQDDAHIICTPDQLDEEIKRVLEFVRDVMAIFGFEYEIEISTRPEKSIGSDADWERATGALMNALKDLELPHDVNEGDGAFYGPKIDIKLKDALDRRWQCATIQCDFTLPERFDLTYVGKDGEKHRPVMLHRVILGAIERFIGVLIEHYAGNFPLWLAPVQAVVINVTDNQADYAKSVSDALRAAGVRVQCDLRNEKLGFKIREAQVDKIPYMLVVGDTEMSDGTVAPRFRSGKNLEPMSPEDFARFVQEECDQYR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_ANAD2
Sequence: MEGLTDRQLEVLRFIASQIEDHGYPPTIREIGEALDIRSTNGVNDHLKALERKGYLSRDPVKSRALIPTSAAREALGGGETGSNVVPLVRGPARPGSRMIEIPIVGRVAAGMPILAQERVEDTVQVDAFLLGTNKKVYGLRVQGDSMIGDGILPGDYVFVKKQLNADDGEIVVAMIDDEATVKRVYFEGDRVRFQPSNPRMAPIYVRHSDFRSTMILGVVVGVYRKLT
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: PYRH_BACSU
Sequence: MEKPKYKRIVLKLSGEALAGEQGNGINPTVIQSIAKQVKEIAELEVEVAVVVGGGNLWRGKTGSDLGMDRATADYMGMLATVMNSLALQDSLETLGIQSRVQTSIEMRQVAEPYIRRKAIRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEADVILMAKNNVDGVYNADPRKDESAVKYESLSYLDVLKDGLEVMDSTASSLCMDNDIPLIVFSIMEEGNIKRAVIGESIGTIVRGK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP, with ATP or dATP as the most efficient phosphate donors.  Is also able to phosphorylate 5-fluoro-UMP and 6-aza-UMP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Is predominantly localized near the bacterial membranes.
Protein: RUVA_LACH4
Sequence: MYEYFEGIVTVITPSYIVVDVNGVGYKVYSPTPFAYQKGDKAKIFIEQVVRDTGITLYGFQSEDDKGLFLKLLSVSGIGPKSALAIMAAEDANSLAEAIEQGEVKYLTRFPGVGKKTASQIVLDLKGKLRDYVARLDRQDEEQGNISPALNDALLALIALGYTQKEVDRITTKLEEVNADTADQYIKKGLALLLKK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ATP6_HAEIE
Sequence: MFGQTTSEYISHHLSFLKTGDGFWNVHIDTLFFSILAAVIFLFVFSRVGKKATTGVPGKMQCLVEIVVEWVNGIVKENFHGPRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQFAGLFGIHYLRAVPTADISATLGMSICVFFLILFYTIKSKGFKGLVKEYTLHPFNHWAFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANMAIAALGIPLHLAWAIFHILVITLQAFIFMMLTVVYLSIAYNKADH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CMOB_SALTY
Sequence: MIEFGNFYQLIAKNHLSHWLETLPAQIASWQREQQHGLFKQWSNAVEFLPEMTPWRLDLLHSVTAESETPLSEGQLKRIDTLLRNLMPWRKGPFSLYGVDIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHLWRMIGAGAHLAVGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNEGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSAPALKKWLEKCGFIDVRIADVCVTTTEEQRRTEWMVTESLADFLDPNDRSKTVEGYPAPQRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: UPPP_NEIM0
Sequence: MDFLIVLKALMMGLVEGFTEFLPISSTGHLIVFGNLIGFHSNHKVFEIAIQLGAVLAVVFEYRQRFSNVLHGVGKDRKANRFVLNLAIAFIPAAVMGLLFGKQIKEHLFNPLSVAVMLVLGGLFILWVEKRQSWAEPKIADVDALRPIDALMIGVAQVFALIPGTSRSGSTIMGGMLWGIERKTATEFSFFLAVPMMVAATAYDVLKHYRFFTLHDVGLILIGFVAAFVSGLVAVKALLRFVSKKNYIPFAYYRIVFGIAIIILWLSGWISWE
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYL_BACCN
Sequence: MSFNHQEIEKKWQAYWEENKTFRTPDETDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEKNINTFRNQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLFEKGLAYVDEIPVNWCPALGTVLANEEVIDGKSERGGHPVERRPMKQWMLKITAYADRLLEDLDELDWPESLKDMQRNWIGRSEGAEVHFNIDGTDKKFTIFTTRPDTLFGATYCVLAPEHALVAEITTEDQKGAVEAYIDVVKSKSDLERTELAKEKTGVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPAHDERDYEFAKTFDLPMKEVVKGGDITKEAYTADGEHIDSAFLNGLNKEEAIAKMIEWLEVTGAGNQKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTMTAVKEEELPLVLPKTDNIRPSGTGESPLANIDEWVNVVDPETGKKGRRETNTMPQWAGSCWYYLRYIDPNNNEALVDPEKAKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDIGVVPTKEPFQQLFNQGMILGENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLDRVWRLFVQENGELSEKITDAPNKELEKAYHQTVKKVTEDYEELHFNTAISQMMMFINDAYKAETLPKEYVEGFVKLLAPVAPHIAEELWSKLGYNETITYASWPTFDESKLVEDEVEIVVQVMGKVRAKLKMKKDASKEEMEQLALEEVKEQIEGKTVRKVIVVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_AETCO
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UPPP2_CLOAB
Sequence: MYTNLIFIFKIILEGIIEGVTEFLPVSSTGHMIILGSIIGFKEGAKPVSLYGAEYIHMFEIIIQLGAILAIVVLYWDKIFSALKPSNLFPSMKEHEKSGIGVVGEFFVKGYNTMPGFKFWTNIVVACIPAIVIGLPFQKKIDKLLFFPAPVAAALMVGAVWMIFAENKYRKRAKIKSVDEITIKQAIVIGCFQCLALWPGMSRSASTIIGAWIVGVATVAGAEFSFFLAIPMMLGASLLFLIKNSVVLSSVQILGLAVGFIVAFIVALVVVDRFISFLKKKPMRIFAVYRLAIGIIVLVLGFTKVIS
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 2, Bacitracin resistance protein 2, Undecaprenyl pyrophosphate phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL15_THET8
Sequence: MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: KL40B_DANRE
Sequence: MALPIDPMEEPRMYQQTLLQDGLYDLLESDMMVDCVLKIKDKEFPCHRLVLAACSSYFRAFFKSGVEESKQREIVLEDVEPGVMGIILKYLYTSNINVTEQNVQDIFALSNMLQIPSIFTVCVSFLQKRLSLSNCLAIFRLGLMLDCPRLAISARNFACERFQFITRDEEFLQLTPSELAAVLASDSLNVETEQDVFEALIKWVGHDQENRIGDLPDLLDCIRLRLVPRDYFVKNVEKHEWLSSNPEITKKLQLVKDAHAGKLPELKKTKNKKSPSEEGQKKGDEEEVEEEEEQEERLPGILNDNLRFGMFLRELIFLINDSASVAYDPTGNDCYVASVSTQIPKNHCSLVTKENQIFVAGGLFFDEQSKDEQIYSYFLQFDPASSDWMGMPPIPSPRFLFGMGEAENFIFVIGGREMKEGENILNTVMVYDRQFLKWAESDPLPYLVYGHGVVSHNEMIYVIGGKGENKECLNRVCAYDIKTHQWKDLAPLNTARSLFGVTIHKNNIYVVAGVTDSGLTGSAEVYDIKTNKWSEFVEFPQDRSSLSLVSVSGVLYAVGGFAMFPKEDSDDLMPLEMNDIWRYDESERTWSGILRENRYASGATVLGVRLNTLRLTKM
What is the function of this protein?
ubstrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex (By similarity).  Required for skeletal muscle development (PubMed:23746549).
What are the official names of this protein?
Kelch-like protein 40b, Kelch repeat and BTB domain-containing protein 5b.
What is the protein family that this protein belongs to?
Belongs to the KLHL40 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, myofibril, sarcomere, I band.
Protein: TRUA_ECO57
Sequence: MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MSCL_LACCB
Sequence: MLKEFQKFIMRGNVLDLAVGVIIGSAFTGLVTSLTKNLINPILSMFAGKADLSGLYFTILGAKFTYGNFINDVLNFLIIAFVVFLLVKGINRILPSKPAKPAGPTQEELLTEIRDLLKQDQQV
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.