PharMolix/UniProtQA huggingface dataset:
Protein: Y3501_SHESW
Sequence: MEKIFERLMYASRWIMAPIYLGLSLVLLGLGIKFFQEIFHVLPIIFEMREVDLVLVTLSLIDITLVGGLIVMVMFSGYENFVSQLDVGEDSEKLSWLGKLDSGSLKNKVAASIVAISSIHLLKIFMNVENISNDKIMWYLLIHITFVLSAFAMGYLDKITRK
What are the official names of this protein?
UPF0114 protein Sputw3181_3501.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y003_METJA
Sequence: MKGKRIAIVSHRILNQNSVVNGLERAEGAFNEVVEILLKNNYGIIQLPCPELIYLGIDREGKTKEEYDTKEYRELCKKLLEPIIKYLQEYKKDNYKFILIGIENSTTCDIFKNRGILMEEFFKEVEKLNIIIKAIEYPKNEKDYNKFVKTLEKMIK
What are the official names of this protein?
Uncharacterized protein MJ0003.
Protein: NUOF_RICAH
Sequence: MLKEEDKIFTNLHGGQIHDLKSSKKRGDWDNTKALLDKGRDFIIEEIKKSGLRGRGGAGFSTGMKWSFMPKNSEKPCYLVVNADESEPGTCKDRDILRFEPHKLIEGCLLASFAIGANNCYIYIRGEFYNEASNIQRALDEAYKDRLIGKNACGSGFDCNIYLHRGAGAYICGEETALLESLEGKKGMPRLKPPFPAGFGLYGCPTTINNVESIAVVPTILRRRASWFASIGKPNNTGTKIFCISGHVNKPCNVEEAMGISLKELIEKYAGGVRGGWDNLKAIIPGGSSVPLLPKSLCEVDMDFDSLRTVGSGLGTGGIIVMDKSTDIIYAIARLSKFYMHESCGQCTPCREGTGWMWRVMIRLVKGNAKKSEIDELLNVTKEIEGHTICALGDAAAWPIQGLIRHFRSEIEDRIKSYSVAIS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit F, NADH dehydrogenase I subunit F, NDH-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
Protein: PUN1_SCHPO
Sequence: MGMGFNPIKALFTGIGTVCVGVGALLSILCIINQTQHNIAFQNIYFIQLNTTSIFSVANQTAVVNNTSNLLNELTGTLVDTLETYIDQGATDLIEQVEQEMKDVSELPDWYSIGLWNYCQGNSSDYTNPTYCSTPSPSYYFNPLTMLETSINNATGSQINITLPSEVDLGLKVLKGACYAMRAMYILGFIFFALTIVSIVISCLPFFGPLFLNVFSFFATIFTFIAAVIAVATYRIAISELEKNIEILNIPIVLGKKIYAYSFLSAAAGLAACILYFIGNLTSGYSPL
What is the function of this protein?
Contributes to the wild-type cellular response to nitrogen stress through signaling pathways that regulate the expression of genes involved in amino acid biosynthesis.  Required for wild-type filamentous growth, cell growth, and cell-cell adhesion (By similarity).
What are the official names of this protein?
SUR7 family protein pun1.
What is the protein family that this protein belongs to?
Belongs to the SUR7 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell tip. Cell septum.
Protein: RISB_METKA
Sequence: MSEIRLGLVVTEFNREITYAMEELAVQHAKDLGAKVVERVLVPGSFEVPLAVRKLLERDDIDAVVTLGAIIKGDTDHDQAIAQQAFRKIQDLMVEYGKPVALGISGPGMTRMEALERVHYAKRAVEAAVKMVRRLRELEGE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SIS_LYMST
Sequence: MLSSVALRYLLVLSLAFLAVVTSSRTQSRFASYELMGTEGTECVTTKTISQICYQCATRHEDSFVQVYQECCKKEMGLREYCEEIYTELPIRSGLWQPNK
What is the function of this protein?
Stimulates integumental Na(+) uptake.  Controls the activity of sodium pumps in the integument, pericardium, ureter and nephridial gland.
What are the official names of this protein?
Sodium-influx-stimulating peptide.
Protein: UREG_BURMA
Sequence: MNAPRFAAPARRTKKLPPLRVGIGGPVGSGKTTLLEMLCKGMRERYDLVAITNDIYTKEDQRLLTIAGALPEARIMGVETGGCPHTAIREDASINLEAVERMLARFPDADIVFIESGGDNLAATFSPELSDLTIYVIDVAGGEKIPRKGGPGITKSDLLVINKTDLAPLVGANLEVMASDTRKMRGERPYVMCNLKALDGVADVIAFIENKGLLTV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBPAP_PYRNV
Sequence: MRVTVSIIKADVGGFPGHAHVHPKMLEYAAAKLKEAQKRGVIIDYFVYNVGDDISLLMTHTKGEDNKDIHGLAWETFKEVTDQIAKRFKLYGAGQDLLKDAFSGNIRGMGPQVAEMEFEERPSEPIIAFAADKTEPGAFNLPLYKMFADPFTTAGLVIDPSMHEGFIFEVLDVVEHKVYLLKTPEDAYSLLGLIGTTGRYIIRKVFRRADGAPAAANSVERLSLIAGRYVGKDDPVLLVRAQSGLPAVGEVLEAFAHPHLVHGWMRGSHAGPLMPARFISVDPERRIAIGPKMTRFDGPPKVGALGFQLHEGYLEGGVDLFDDPAFDYVRQTAAQIADYIRRMGPFQPHRLPPEEMEYTALPKILAKVKPYPADQYEKDRKKYIEAVVKGAKVEESQHD
What is the function of this protein?
Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
What are the official names of this protein?
Fructose-1,6-bisphosphate aldolase/phosphatase, FBP A/P, FBP aldolase/phosphatase.
What is the protein family that this protein belongs to?
Belongs to the FBP aldolase/phosphatase family.
Protein: DCD_NEIG2
Sequence: MSIKSDKWIRRMSEEFGMIDPFEPNQIKEADGQRIISYGTSSYGYDIRCANEFKIFTNINSTIVDPKNFDPKNFVTVEDDCCIIPPNSFALARTVEYFRIPRNVLTVCLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGVAQVLFFESDEVCETSYKDRNGKYMGQTGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PUR9_BACC4
Sequence: MKKRALVSVSDKTGVVEFVKGLLEQGIEVISTGGTKKLLEENGLQVIGISEVTGFPEIMDGRVKTLHPNIHGGLLAVRDNETHVTQMNELGIEPIDFVVVNLYPFKETIAKPDVTFADAIENIDIGGPTMIRSAAKNHKFVSVIVDPVDYDIVLAELKENGEVAEETKRKLAAKVFRHTAAYDALISNYLTEQMGEESPETLTVTFEKKQDLRYGENPHQKATFYKAPFAATSSVAYAEQLHGKELSYNNINDADAALSIVKEFTEPAVVAVKHMNPCGVGVGTNIHEAYTRAYEADPVSIFGGIIAANREIDKATAEKLHEIFLEIVIAPSFSQEALEVLQSKKNLRLLTINIEKATSASKKLTSVQGGLLVQEEDTLSLDESTISIPTKREPSEQEWKDLKLAWKVVKHVKSNAIVLAKDDMTIGVGAGQMNRVGSAKIAITQAGEKAQGSALASDAFFPMPDTLEEAAKAGITAIIQPGGSIRDEDSIKVADTYGIAMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: GLO2_NEIG1
Sequence: MKITPVKALTDNYIWMIQHGNHAVCVDPSEPSPVLEFLVRNRLMLAQTWVTHPHPDHEGGAAALWRGYMESPVYGESDIEAATHTVTAGTRFTFGNGQVTVWATPGHTDRHTSYLLETSDGIHVFCGDTLFSAGCGRVFTGTVEQLYDNFQRFNQLPEGTLFYPAHEYTAANLRFAAHIEPDNADIQTALKAAEHTPTLPVTLAHERRVNPFLRTEIPAVRQRAEALVGKTLNSGLEVFAALRELKNAYR
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: BLAC_STRGR
Sequence: AAAPDIPIANVNA
What are the official names of this protein?
Beta-lactamase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
What are the subcellular locations of this protein?
Secreted. Membrane.
Protein: F216A_BOVIN
Sequence: MPNQGPVSDWTECSSSAEPPAVARAEGGGGGSAGHSYYQNSKDRIKDGHKVNSPRAKLQELWKMPQTVHTPKSMTEPSFLKHPDLTLVEKHYLCSVAKIYNANYLRTLMKRHYMHVIQRSSQKPGVLTHHRGHLSSRYSQKQHYPCTTWRHQLEREDLGPPNTAAASAPEMIQHSLWRPVRNKEGLKTGYASKTRCKSLKIFRKPGRPFMQSVSANDSESYMNEEKKEEDLLNKCMQSMSIEEQGEHLMLT
What are the official names of this protein?
Protein FAM216A.
What is the protein family that this protein belongs to?
Belongs to the FAM216 family.
Protein: LIPA_NITEU
Sequence: MAADTHQRGAAKTARNPVKIDLEQSGQLLRKPSWIRVRSSNSQKYLEVKRLLRENRLHTVCEEASCPNIGECFGRGTATFMILGDLCTRRCPFCDVAHGRPHAPDPDEPMHLANSIAVLKLNYVVITSVDRDDLRDGGAQHFADCIRAIRTQSPQTRIEILVPDFRGRLEVALEKLSACPPDVMNHNLETVPRLYKQCRPGADYMHSLQLLKDFKAAFPHIPTKSGLMLGLGETDEEIIEVMRDLRAHQVDMLTVGQYLQPSKGHHPVMRYVSPEDFKTFERIATNLGFSHAACGPMVRSSYHADQQAHEAGIE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZSC18_HUMAN
Sequence: MLPLEKAFASPRSSPAPPDLPTPGSAAGVQQEEPETIPERTPADLEFSRLRFREFVYQEAAGPHQTLARLHELCRQWLMPEARSKEQMLELLVLEQFLGILPDKVRPWVVAQYPESCKKAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVYERHMDPLLLPGELASPSQALGAGEIPAPSETPWLSPDPLFLEQRRVREAKTEEDGPANTEQKLKSFPEDPQHLGEWGHLDPAEENLKSYRKLLLWGYQLSQPDAASRLDTEELRLVERDPQGSSLPEGGRRQESAGCACEEAAPAGVLPELPTEAPPGDALADPPSGTTEEEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKRPHPEDGDGQSLEGVSSSGDSAGLEAGQGPGADEPGLSRGKPYACGECGEAFAWLSHLMEHHSSHGGRKRYACQGCWKTFHFSLALAEHQKTHEKEKSYALGGARGPQPSTREAQAGARAGGPPESVEGEAPPAPPEAQR
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 18, Zinc finger protein 447.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CDC6_PYRFU
Sequence: MNEGEHQIKLDELFEKLLRARKIFKNKDVLRHSYTPKDLPHRHEQIETLAQILVPVLRGETPSNIFVYGKTGTGKTVTVKFVTEELKRISEKYNIPVDVIYINCEIVDTHYRVLANIVNYFKDETGIEVPMVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLRDILTQRAEEAFYPGVLDEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWKAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGDVYAVYRELCEYIDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTSYKIRNVLRYDYSIQPLLTISLKSEQRRLI
What is the function of this protein?
Involved in regulation of DNA replication.  May play essential roles in origin recognition and cell cycle control of replication.  Binds specifically to the oriC region, which alters the topological structure of the DNA and introduces localized melting of the DNA duplex.  May recruit the MCM helicase onto the oriC region.  Shows weak ATPase activity in the absence of DNA.
What are the official names of this protein?
ORC1-type DNA replication protein.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: COAX_ANAMM
Sequence: MIVAVDVGNTSTKIALCENGTVVDKWRISTCGKRTAAEYFSCISVLASRRSADILAGVRGAAISSVVPVVNRHVEELFERFFNISPVFITNSHADLFGLKICLAQPTIGADRVADLVAAKTLWPTSDLLVIDMGTATVFNLLDRNGGLYGQVVAPGVSCLVHSMRECTALLPQTLVRESEKIVCDSTAASLEAGLYWGYRAMVEGITKQIMRESTRTLRVIATGGGVGLFRNCDYLNHIDELLTIKGIVQIYEKTQG
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S399A_XENLA
Sequence: MDDFSSISLLSLAMLVGCYVSGIIPLAVNFSEEKLKLVTVLGAGLLCGTALAVIIPEGVHALYEEILEAKHHDLGEIHKVKEAETGAETSVAHEHDHSNLHAYIGVSLVLGFVFMLLVDQIGSSHMHSADDPEAARAASSKITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPVLSMLTYLGLSKSSKEALSEINATGVAMLFSAGTFLYVATVHVLPEVGGMGHSHKPDVGAAKGLSRLEVCALVLGCLIPLVLSIGHQH
What is the function of this protein?
Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis.  Participates in the zinc ions efflux out of the secretory compartments.  Regulates intracellular zinc level, resulting in the enhancement of AKT1 and MAPK3/MAPK1 (Erk1/2) phosphorylation in response to the BCR activation (By similarity).  Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1 (By similarity).  Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process (By similarity).
What are the official names of this protein?
Zinc transporter ZIP9-A, Solute carrier family 39 member 9-A, Zrt- and Irt-like protein 9-A, ZIP-9-A.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRMD_SHEB8
Sequence: MWLGVITLFPEMFRAVTDFGVTGRAVKNGLLELHTWNPRDFTHDRHNTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQQGVTELAQSSRLILVCGRYEGIDERIIQTEVDEEWSIGDYVLSGGELPAMTLIDSVSRLVPGVLGKQASAEQDSFSDGLLDCPHYTRPESLDGVDVPAVLLSGNHEQIRLWRLQQSLGRTLLRRPELLQNLALTDEQTTLLAQFVEAMNKHA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_CAMJR
Sequence: MKNFDKFSTNEEFSSVYKIGKKWHCEGVIIFYLNSYEKKIAVVASKKVGKAVVRNRSKRILRALFAKFERYLRDGKYIFVAKNEITELSFSRLEKNLKWGLKKLECFK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: ATPE_SOLUE
Sequence: MPDTLELEVATPERELVREQVTEVQVPAAQGYLGVLPGHAPLLGLLGIGTLTYMVGGNKRHISVHGGFLEVLEDHVRVLADVAERAEEIDIQRAKAALERSQREALNPALGVDPAEALAATMRAEARLATADKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MYOG_COTJA
Sequence: MSDFILKKSFFPEQRFYDGENFLGSRLQGYEAATFPERPEVSLCPESRGALEEKDSTLPDHCPGQCLPWACKICKRKTVSIDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSSIQYTERLQSLLSLNQQERDERELRYRPTAPQPAAPSECGSGSSSCSPEWSTQLEFGTNPTDHLLSDDAAEDRNLHSLSSIVESIAVEDVAVTFPEERVQN
What is the function of this protein?
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.  Induces somite cells to differentiate into myoblasts.  Probable sequence specific DNA-binding protein (By similarity).
What are the official names of this protein?
Myogenin, Myogenic factor 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: INSL3_DROME
Sequence: MGIEMRCQDRRILLPSLLLLILMIGGVQATMKLCGRKLPETLSKLCVYGFNAMTKRTLDPVNFNQIDGFEDRSLLERLLSDSSVQMLKTRRLRDGVFDECCLKSCTMDEVLRYCAAKPRT
What are the official names of this protein?
Probable insulin-like peptide 3, dILP3, Insulin-related peptide 3.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBN_SYNJA
Sequence: MESTLSLVVAIAAITICITAFAIYTAFGPPSKNLQDPYEMHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: Y1573_MYCBO
Sequence: MASVELSADVPISPQDTWDHVSELSELGEWLVIHEGWRSELPDQLGEGVQIVGVARAMGMRNRVTWRVTKWDPPHEVAMTGSGKGGTKYGVTLTVRPTKGGSALGLRLELGGRALFGPLGSAAARAVKGDVEKSLKQFAELYG
What are the official names of this protein?
Uncharacterized protein Mb1573.
Protein: CH60_LISIN
Sequence: MAKDIKFSEDARRAMLRGVDQLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDPFENMGAKLVSEVASKTNDVAGDGTTTATVLAQAMIQEGLKNVTAGANPVGVRRGIEKAVATAIEELKAISKPIESKESIAQVAAISSGDEEVGKLIAEAMERVGNDGVITIEESKGFATELDVVEGMQFDRGYTSPYMVTDSDKMEAVLEKPYILITDKKINNIQEILSVLEQVVQQGRPMLIIAEDVEGEAQATLVLNKLRGTFNVVAVKAPGFGDRRKAMLEDIAVLTGGQVITEDLGLELKTATVDQLGTANKVVVTKDDTTIVEGAGDSTQISARVNQIRAQMEETTSEFDREKLQERLAKLAGGVAVVKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVSIYNKVAALEAEGDVETGINIVLRSLEEPVRQIAHNAGLEGSVIVERLKHEAVGVGFNAANGEWVNMIDAGIVDPTKVTRSALQNASSVAALLLTTEAVVADQPDENGPAAGPDMGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRD_SHELP
Sequence: MADAKELKQVLTGPIISNNPIALQILGVCSALAVTSKMETALVMTIALTAVTALSNLFISMIRNHIPSSVRIIVQMTIIASLVIVVDQVLQAYAYDVAKQLSVFVGLIITNCIVMGRAEAYAMKTPPMMSFMDGIGNGLGYGAILLSVGFVRELFGNGSLFGVEILSKISEGGWYQPNGLLLLPPSAFFLIASLIWIIRTIKPEQVEAKG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YAG1_SCHPO
Sequence: MLNRSKKRNGCYFWVNGSSDEIRYVAVKASPKVNWKTHIIWRSLKNVKCIDSFHGNNEILGAGSSTGNISLLSVKHPEFQAVVTPGYARPCNSLAFSETEHLVAGFAKSRNESSLKLWDLNSLLSDPKSSPLMQSSTLDGVSSVCYKKDTPLLLTGSTSRSVHIIDTRQQLDSVSSVNTQYYSNIVVDPFSPNYFAANSYDGDIAIFDTRYFKSDNYLQIILRNENKKPKNPQLFALKYSEWKPGQLAVLSNNSITLRQLLPCVNGNEGSANNSVFVNYEKKYPVKPNSQCSGIDFFTPSTAFPTHVQILGVINEQPKLFSVHDEVIPFSFNPYNDLIFSFKEKLYPLNSSPFNTLSDVPQFDVSEFVDENSFDSSSSCSSKVFLTTRNNSINSEDSAHEVLLSYNRVLGSDIQGTILDRVKKGYQFDSQKNSELVSDLYLKDLWSWIHLSHRQSEESLFGDTGDTDFSYQGALGIWFMDTELTSMSDVFEAKESKFLEKKILRLARDVIERLDLDIFTSIQTKRPLRQLALLACGLGMSNDDLLLEIRRLIRKNEHVKAAGLALFHGKIENVVRILSSGNELEKTISTAVAGYITSQGLSNFGSDSLWKEMSRNLSTELEDPYLRAIFAYVSNSDWRDVLDEVSLSLKDRLGIALRFLPDDDLSNYLCDLCHTTVQSGDPEGLLLTGLTPLGMELLQNYIDHTSDVQTAALIAAFVVPKKFLDKRAEDWTESYRELLNRWKLYRERAKFDIFRTELSKNHTGEITRKATEPSIRIICNFCRKPIFPFSNRNECNNLPTPIQRGVSKAGPAKHLGKSCPHCGQPLPKCSVCGFSLGDEDVPQKDDFSQKPQNYVKEVNLQKSRFGLWFSFCLNCGHGAHASHASEWFSTHTICPVPNCDCECKLK
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C12G12.01c.
What is the protein family that this protein belongs to?
Belongs to the WD repeat mio family.
Protein: TRPC_BACAN
Sequence: MGTILDKIVNQKKKEVAALYETYTPVKEKRKTRSLVKALEQFTVIAEVKRASPSKGDINLHVDVRKQVKTYEECGAGAVSVLTDGQFFKGSFYDLQTAREESSIPLLCKDFIIDKIQIDRAYEAGADIILLIVAALTKEKLKELYSYVLEKGLEAIVEVHDEQELEIAIQLNPHVIGINNRNLKTFEVDLSQTEKLGKRLNEEKLLWISESGIHSKEDIIRVKRAGAKGVLVGEALMTSSSIHTFFEDCKVNI
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: YGN2_YEAST
Sequence: MEKNNTTKPRKIGPYFLSKVTITYWLDGCVFLSVPASEISISNIAGSIPSINCWVISTGKPLSLEILADALSKSSSWAPDLKLQEWQIISSYQYKLLFVPQCGQVLSKGST
What are the official names of this protein?
Putative uncharacterized protein YGL132W.
Protein: RAPD_BACSU
Sequence: MISKFIEKRMLNMLDEWYSAMSKRKMNHVCTLKEKIDQHLPKIKKNTKLWMRYQLFQARHQLLFENQNGLDSLFDGLYGLEDKMDDELKYYLYFFSGLYEMVKTAPKHAVHHFKKAEQYLAAIHNTFEAADLYYQTAGAYYLMKSPPLSVQYVKKALHIYLHQFGYIKKVITCKLLLAVNYIDQERYEKAEQLFKEIIKKTQQLHDENLLCHAYYNLGFLKATEKKDQEALLYFRKVLKNQEFEMNSPVSYLHCVYESVRALFKTGNITEAKAVLQKGKELSEKVDIQTIYLKLKTLEALYTSAEDPYEQLLEYVLELEKIEAWVDLEVLLEDITEYYKKKDDFEKAAFFIMRG
What are the official names of this protein?
Regulatory protein RapD.
What is the protein family that this protein belongs to?
Belongs to the Rap family.
Protein: PDXY_PSEE4
Sequence: MKRTPHLLAIQSHVVFGHAGNSAAVFPMQRVGVNVWPLNTVQFSNHTQYGQWAGEVLAPAQIPALVEGISNIGELGNCDAVLSGYLGSAEQGRAILAGVARIKAVNPKALYLCDPVMGHAEKGCIVPAEVSEFLLEEAVAKADILCPNQLELDSFCGRRAESLEDCVGMARGLLERGPRIVLVKHLNYPGRADDAFEMLLVTGEESWHLRRPLLAFPRQPVGVGDLTSGLFMARLLLGDSDVQAFEFAAAAVHEVLLETQACASYELQLVRAQDRIAHPRVRFEAQRLLY
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: MOAA_HAEI8
Sequence: MQSIPIKNVGESRLVDPFQRQYYYLRLSITDQCNFRCTYCLPDGYQPEANKPSFLTLKEIIHLAQAFAEMGTEKIRLTGGEPTLRKDFISIAESIANIDGIRQLAVTTNGYRMAKDVADWKQAGITSINVSVDSLDPKMFHQITGINKFDDVMRGIDRAFEVGYNKVKVNSVLMKNLNDKEFEQFLAWVKHRPIQMRFIELMQTGEMDSFFDRYHLSGQILADKLLKNGWTLQHKSHTDGPAKVFTHPDYAGEIGLIMPYEKNFCASCNRLRVSAKGKLHLCLFGEEGIELRDLLQSHEQQAILQARIFAALQGKREHHYLHIGDTGVRNHLASIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: DPHB_METHJ
Sequence: MLIFVGLGLYDLDDISLKGLQAIKEADAVFLETYTSVLTGTTIEQMREKYGKDLIILKRQDVEQKPEPILTAAKNGIAVFLTGGDPMVSTTHADLRIRAHEQGIPTKIIHGSSIVSAVSGLTGLQNYRFGKSCSIPYPAPKWFPKTPLDTILANLKQNLHTIVYLDIQENRYMSVHEGIELLEKLMEGSTDSIPLFVGIARAGSNSPVVAAGSSERLKLVDFGPPLHILVVPASLHEIEEEYLKNFAGYDPQ
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.